GeneID geneLength Means-Adult_Control Means-Adult_cKO log2Ratio(Adult_cKO/Adult_Control) Up-Down-Regulation(Adult_cKO/Adult_Control) Probability Symbol Description KEGG Orthology GO Component GO Function GO Process Blast nr 100034726 539 111.3366667 0.923333333 -6.91386151 Down 0.989553951 Gm15772 ribosomal protein L26 pseudogene K02898|1|2e-74|279|cge:100760077|large subunit ribosomal protein L26e - - - gi|537145497|gb|ERE69430.1|/6.25371e-75/60S ribosomal protein L26-like protein [Cricetulus griseus] 68436 495.19 34.85 77.03333333 1.144324198 Up 0.842068148 Rpl34 ribosomal protein L34 K02915|1|3e-52|206|mmu:68436|large subunit ribosomal protein L34e GO:0043231//intracellular membrane-bounded organelle;GO:0015934//large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0015934//large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|725571770|ref|XP_010338387.1|/2.86167e-61/PREDICTED: LOW QUALITY PROTEIN: 60S ribosomal protein L34 [Saimiri boliviensis boliviensis] 66184 941 28.85666667 15.19666667 -0.92514975 Down 0.786575275 Rps4l ribosomal protein S4-like K02987|1|3e-148|526|cge:100760991|small subunit ribosomal protein S4e GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity;GO:0003723//RNA binding GO:0006412//translation;GO:0008283//cell proliferation;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0006613//cotranslational protein targeting to membrane;GO:0032502//developmental process gi|148678798|gb|EDL10745.1|/5.20936e-148/RIKEN cDNA 1110033J19 [Mus musculus] 19941 564 193.9533333 305.3933333 0.654958998 Up 0.758621987 Rpl26 ribosomal protein L26 K02898|1|3e-76|285|cge:100760077|large subunit ribosomal protein L26e - - - gi|537145497|gb|ERE69430.1|/9.99982e-77/60S ribosomal protein L26-like protein [Cricetulus griseus] 27367 1361 119.7133333 166.4066667 0.475129388 Up 0.68596036 Rpl3 ribosomal protein L3 K02925|1|0.0|792|mmu:27367|large subunit ribosomal protein L3e GO:0015934//large ribosomal subunit;GO:0031981//nuclear lumen GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0070670//response to interleukin-4 gi|74185237|dbj|BAE30097.1|/0/unnamed protein product [Mus musculus] 666899 524 1.67 0.32 -2.383704292 Down 0.643057279 Gm12191 ribosomal protein L30 pseudogene K02908|1|1e-59|230|pale:102897778|large subunit ribosomal protein L30e GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|664777237|ref|XP_008507911.1|/3.05585e-60/PREDICTED: 60S ribosomal protein L30-like [Equus przewalskii] 66845 484 51.98333333 65.63666667 0.336452827 Up 0.578528715 Mrpl33 mitochondrial ribosomal protein L33 K02913|1|2e-20|99.8|mmu:66845|large subunit ribosomal protein L33 GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex - GO:0010467//gene expression "gi|269784741|ref|NP_080072.2|/1.55385e-19/39S ribosomal protein L33, mitochondrial [Mus musculus]" 66211 1363.71 277.2766667 221.39 -0.324736158 Down 0.578067998 Rpl3l ribosomal protein L3-like K02925|1|6e-138|492|mmu:66211|large subunit ribosomal protein L3e GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0010467//gene expression gi|755558820|ref|XP_011244871.1|/5.04815e-137/PREDICTED: 60S ribosomal protein L3-like isoform X1 [Mus musculus] 619547 495 90.84333333 72.27666667 -0.329850672 Down 0.575501147 Rpl34-ps1 "ribosomal protein L34, pseudogene 1" K02915|1|2e-52|206|acs:100555733|large subunit ribosomal protein L34e GO:0043231//intracellular membrane-bounded organelle;GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|594102238|ref|XP_006074192.1|/6.57787e-53/PREDICTED: 60S ribosomal protein L34-like [Bubalus bubalis] 107094 4344 10.72333333 7.726666667 -0.47283537 Down 0.569737485 Rrp12 ribosomal RNA processing 12 homolog (S. cerevisiae) K14794|1|0.0|2247|mmu:107094|ribosomal RNA-processing protein 12 GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - - "gi|148709918|gb|EDL41864.1|/0/expressed sequence AA408556, isoform CRA_b, partial [Mus musculus]" 100042173 824 10.64333333 14.22666667 0.418647623 Up 0.564152469 Rps15a-ps6 "ribosomal protein S15A, pseudogene 6" K02957|1|4e-69|263|cjc:100394618|small subunit ribosomal protein S15Ae - - - gi|675706491|ref|XP_009007486.1|/3.18886e-68/PREDICTED: 40S ribosomal protein S15a [Callithrix jacchus] 94064 828 33.50333333 42.21333333 0.333394115 Up 0.557523788 Mrpl27 mitochondrial ribosomal protein L27 K02899|1|7e-66|252|mmu:94064|large subunit ribosomal protein L27 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression "gi|16716447|ref|NP_444391.1|/5.67088e-65/39S ribosomal protein L27, mitochondrial [Mus musculus]" 100502825 678.7 10.43333333 13.77 0.400328403 Up 0.547660687 Rpl37rt "ribosomal protein L37, retrotransposed" K02922|1|5e-48|192|pale:102886771|large subunit ribosomal protein L37e GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0043169//cation binding;GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0043169//cation binding;GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|850272454|ref|XP_012863843.1|/3.24106e-48/PREDICTED: 60S ribosomal protein L37 [Echinops telfairi] 66481 396 196.81 240.8433333 0.291291463 Up 0.547660687 Rps21 ribosomal protein S21 K02971|1|4e-41|168|mmu:66481|small subunit ribosomal protein S21e - - - gi|564345076|ref|XP_006235885.1|/1.44779e-49/PREDICTED: 40S ribosomal protein S21 isoform X1 [Rattus norvegicus] 100359413 403 0.526666667 0.01 -5.718818247 Down 0.530943247 AA413626 ribosomal protein L17 pseudogene K02880|1|4e-14|78.6|phd:102321340|large subunit ribosomal protein L17e - - - gi|507636850|ref|XP_004629263.1|/3.35258e-14/PREDICTED: 60S ribosomal protein L17 [Octodon degus] 59014 2058 11.39 14.3 0.3282474 Up 0.496934823 Rrs1 ribosome biogenesis regulator 1 K14852|1|1e-151|539|mmu:59014|regulator of ribosome biosynthesis GO:0000228//nuclear chromosome GO:0005488//binding GO:0000070//mitotic sister chromatid segregation;GO:0022613//ribonucleoprotein complex biogenesis gi|49022822|dbj|BAC65489.2|/6.02291e-155/mKIAA0112 protein [Mus musculus] 16785 1861 253.8766667 299.8733333 0.240225429 Up 0.491519049 Rpsa ribosomal protein SA K02998|1|7e-158|560|xla:100037080|small subunit ribosomal protein SAe - - - gi|820983550|ref|XP_012351476.1|/3.00651e-158/PREDICTED: 40S ribosomal protein SA isoform X1 [Nomascus leucogenys] 277692 426 0.82 1.663333333 1.0203815 Up 0.491189966 Rps19-ps3 "ribosomal protein S19, pseudogene 3" K02966|1|6e-71|267|ngi:103744615|small subunit ribosomal protein S19e GO:0031981//nuclear lumen;GO:0015935//small ribosomal subunit GO:0019838//growth factor binding;GO:0005198//structural molecule activity GO:0009605//response to external stimulus;GO:0006412//translation;GO:0022618//ribonucleoprotein complex assembly;GO:0006928//movement of cell or subcellular component;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0030099//myeloid cell differentiation;GO:0006613//cotranslational protein targeting to membrane;GO:0006364//rRNA processing gi|12963511|ref|NP_075622.1|/5.69554e-70/40S ribosomal protein S19 [Mus musculus] 94063 1134 31.92 38.10333333 0.255456561 Up 0.484194592 Mrpl16 mitochondrial ribosomal protein L16 K02878|1|3e-129|463|mmu:94063|large subunit ribosomal protein L16 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding GO:0010467//gene expression "gi|19424352|ref|NP_079882.2|/2.78492e-128/39S ribosomal protein L16, mitochondrial precursor [Mus musculus]" 64660 1007 45.63 54.17 0.247511437 Up 0.482934672 Mrps24 mitochondrial ribosomal protein S24 K17403|1|1e-81|305|mmu:64660|small subunit ribosomal protein S24 GO:0000314//organellar small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle - - "gi|13385578|ref|NP_080356.1|/1.04832e-80/28S ribosomal protein S24, mitochondrial precursor [Mus musculus]" 99045 991 23.1 27.78333333 0.266326847 Up 0.481674753 Mrps26 mitochondrial ribosomal protein S26 K17405|1|4e-66|253|mmu:99045|small subunit ribosomal protein S26 GO:0044444//cytoplasmic part;GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle - - "gi|46402169|ref|NP_997090.1|/3.526e-65/28S ribosomal protein S26, mitochondrial precursor [Mus musculus]" 20055 633 242.74 281.7933333 0.215225618 Up 0.46581293 Rps16 ribosomal protein S16 K02960|1|3e-85|316|mmu:100862433|small subunit ribosomal protein S16e - - - - 26451 1112 183.1 213.33 0.220455071 Up 0.464308549 Rpl27a ribosomal protein L27A K02900|1|8e-70|266|hgl:101724905|large subunit ribosomal protein L27Ae GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression gi|820997375|ref|XP_004647393.2|/7.47761e-70/PREDICTED: 60S ribosomal protein L27a-like [Octodon degus] 27050 1879 123.2966667 143.6733333 0.220658517 Up 0.461168152 Rps3 ribosomal protein S3 K02985|1|2e-134|481|pale:102897409|small subunit ribosomal protein S3e GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0001726//ruffle;GO:0015935//small ribosomal subunit GO:0016835//carbon-oxygen lyase activity;GO:0005198//structural molecule activity;GO:0051540;GO:0003677//DNA binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0008134//transcription factor binding;GO:0019900//kinase binding GO:0006412//translation;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006915//apoptotic process;GO:0019080;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0012502//induction of programmed cell death;GO:0006613//cotranslational protein targeting to membrane;GO:0006281//DNA repair gi|795271913|ref|XP_011857417.1|/4.74018e-135/PREDICTED: 40S ribosomal protein S3 isoform X1 [Mandrillus leucophaeus] 665931 834 2.45 3.52 0.52279368 Up 0.455752379 Rplp2-ps1 "ribosomal protein, large P2, pseudogene 1" K02943|1|4e-28|127|hgl:101702556|large subunit ribosomal protein LP2 GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0006412//translation gi|594042682|ref|XP_006045870.1|/6.64581e-29/PREDICTED: 60S acidic ribosomal protein P2 [Bubalus bubalis] 100040970 694 67.71 79.10666667 0.224430363 Up 0.454586483 Rpl14-ps1 "ribosomal protein L14, pseudogene 1" K02875|1|7e-73|275|mmu:67115|large subunit ribosomal protein L14e - - - - 66292 423 220.6 255.07 0.209460436 Up 0.45122043 Mrps21 mitochondrial ribosomal protein S21 K02970|1|3e-32|138|mmu:66292|small subunit ribosomal protein S21 GO:0019866//organelle inner membrane;GO:0000314//organellar small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression "gi|17505220|ref|NP_510964.1|/2.96709e-31/28S ribosomal protein S21, mitochondrial [Mus musculus]" 68028 477 9.026666667 7.303333333 -0.305638255 Down 0.437192072 Rpl22l1 ribosomal protein L22 like 1 K02891|1|1e-46|186|cge:100750612|large subunit ribosomal protein L22e GO:0030529//intracellular ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression gi|148671237|gb|EDL03184.1|/9.69015e-46/mCG6454 [Mus musculus] 94066 917 23.65 27.65333333 0.22561321 Up 0.435001316 Mrpl36 mitochondrial ribosomal protein L36 K02919|1|3e-46|187|mmu:94066|large subunit ribosomal protein L36 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression "gi|16716451|ref|NP_444393.1|/2.71438e-45/39S ribosomal protein L36, mitochondrial [Mus musculus]" 20085 629 111.1233333 127.8433333 0.202215149 Up 0.432312234 Rps19 ribosomal protein S19 K02966|1|5e-76|285|ngi:103744615|small subunit ribosomal protein S19e GO:0031981//nuclear lumen;GO:0015935//small ribosomal subunit GO:0019838//growth factor binding;GO:0005198//structural molecule activity GO:0009605//response to external stimulus;GO:0006412//translation;GO:0022618//ribonucleoprotein complex assembly;GO:0006928//movement of cell or subcellular component;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0030099//myeloid cell differentiation;GO:0006613//cotranslational protein targeting to membrane;GO:0006364//rRNA processing gi|12963511|ref|NP_075622.1|/3.35761e-75/40S ribosomal protein S19 [Mus musculus] 102634812 1833 0.11 0.516666667 2.231730286 Up 0.41498364 LOC102634812 ribosomal protein L39 pseudogene K01081|1|2e-26|123|mmu:50773|5'-nucleotidase [EC:3.1.3.5] - - - - 20116 740 278.7333333 316.0366667 0.181206407 Up 0.409097747 Rps8 ribosomal protein S8 K02995|1|6e-119|428|lve:103070431|small subunit ribosomal protein S8e GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0030490//maturation of SSU-rRNA;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|795270501|ref|XP_011857247.1|/1.70523e-120/PREDICTED: 40S ribosomal protein S8 isoform X1 [Mandrillus leucophaeus] 54217 425 244.01 215.6066667 -0.178538486 Down 0.407894242 Rpl36 ribosomal protein L36 K02920|1|2e-48|192|myd:102775437|large subunit ribosomal protein L36e - - - gi|585689575|ref|XP_006894244.1|/3.60124e-48/PREDICTED: uncharacterized protein LOC102862726 [Elephantulus edwardii] 238323 2534 2.263333333 1.533333333 -0.561777713 Down 0.40725488 Rps6kl1 ribosomal protein S6 kinase-like 1 K04373|1|1e-23|114|pss:102444275|p90 ribosomal S6 kinase [EC:2.7.11.1] GO:0030529//intracellular ribonucleoprotein complex GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|31981933|ref|NP_666356.2|/0/ribosomal protein S6 kinase-like 1 [Mus musculus] 69527 1445 55.79666667 48.95666667 -0.188673605 Down 0.405947948 Mrps9 mitochondrial ribosomal protein S9 K02996|1|0.0|765|mmu:69527|small subunit ribosomal protein S9 GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression "gi|148664506|gb|EDK96922.1|/0/mitochondrial ribosomal protein S9, isoform CRA_b [Mus musculus]" 68836 412 67.45 76.41 0.179943017 Up 0.39727895 Mrpl52 mitochondrial ribosomal protein L52 K17433|1|2e-65|249|mmu:68836|large subunit ribosomal protein L52 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression "gi|30348981|ref|NP_081127.1|/1.57028e-64/39S ribosomal protein L52, mitochondrial precursor [Mus musculus]" 20042 535 342.2833333 385.09 0.170004614 Up 0.394881342 Rps12 ribosomal protein S12 K02951|1|3e-71|269|oaa:100075031|small subunit ribosomal protein S12e GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|14277700|ref|NP_001007.2|/2.03754e-70/40S ribosomal protein S12 [Homo sapiens] 59050 2686 25.8 22.43666667 -0.20151271 Down 0.394571063 Nsa2 NSA2 ribosome biogenesis homolog K14842|1|3e-140|502|rno:171456|ribosome biogenesis protein NSA2 GO:0032991//macromolecular complex;GO:0031981//nuclear lumen - GO:0042254//ribosome biogenesis gi|351701860|gb|EHB04779.1|/9.42239e-140/ribosome biogenesis protein NSA2-like protein [Heterocephalus glaber] 94062 1531 52.83333333 59.94333333 0.182150877 Up 0.393442777 Mrpl3 mitochondrial ribosomal protein L3 K02906|1|0.0|696|mmu:94062|large subunit ribosomal protein L3 - - - - 27393 1850 40.75333333 46.06666667 0.176805144 Up 0.386616646 Mrpl39 mitochondrial ribosomal protein L39 K17420|1|0.0|641|mmu:27393|large subunit ribosomal protein L39 GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0036094//small molecule binding - "gi|364023817|ref|NP_059100.3|/0/39S ribosomal protein L39, mitochondrial [Mus musculus]" 67186 441 352.2733333 393.07 0.158090989 Up 0.3793392 Rplp2 "ribosomal protein, large P2" K02943|1|9e-30|130|hgl:101702556|large subunit ribosomal protein LP2 - - - - 76846 703 351.6733333 392.45 0.158272917 Up 0.3793392 Rps9 ribosomal protein S9 K02997|1|2e-95|350|cfa:476387|small subunit ribosomal protein S9e GO:0031981//nuclear lumen;GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity;GO:0003723//RNA binding GO:0006412//translation;GO:0008283//cell proliferation;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0006613//cotranslational protein targeting to membrane gi|545487328|ref|XP_533590.3|/1.44732e-94/PREDICTED: 40S ribosomal protein S9 [Canis lupus familiaris] 110954 798 338.64 377.9533333 0.158455719 Up 0.379245177 Rpl10 ribosomal protein L10 K02866|1|5e-132|472|phd:102327737|large subunit ribosomal protein L10e GO:0043231//intracellular membrane-bounded organelle;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|556739248|ref|XP_005965182.1|/4.26154e-131/PREDICTED: 60S ribosomal protein L10 isoform X1 [Pantholops hodgsonii] 270106 794 288.3466667 322.8133333 0.162895824 Up 0.378803265 Rpl13 ribosomal protein L13 K02873|1|3e-99|363|xla:100049095|large subunit ribosomal protein L13e GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane "gi|148679762|gb|EDL11709.1|/2.11775e-98/mCG19578, isoform CRA_b [Mus musculus]" 20102 992 277.7566667 309.4566667 0.155915863 Up 0.378474181 Rps4x "ribosomal protein S4, X-linked" K02987|1|3e-151|536|ecb:100034075|small subunit ribosomal protein S4e - - - - 66229 2606 19.03333333 21.69 0.188501808 Up 0.373603746 Rpl7l1 ribosomal protein L7-like 1 K02937|1|4e-50|202|sko:100367525|large subunit ribosomal protein L7e GO:0032991//macromolecular complex - - gi|27754134|ref|NP_079709.2|/3.63028e-123/60S ribosomal protein L7-like 1 [Mus musculus] 67248 434 40.92 45.88 0.165059246 Up 0.372193388 Rpl39 ribosomal protein L39 K02924|1|1e-26|120|rro:104671531|large subunit ribosomal protein L39e - - - - 18100 1055 33.28666667 37.37666667 0.167193506 Up 0.366815224 Mrpl40 mitochondrial ribosomal protein L40 K17421|1|1e-100|368|mmu:18100|large subunit ribosomal protein L40 GO:0000313;GO:0043231//intracellular membrane-bounded organelle - - "gi|255003746|ref|NP_035052.2|/1.0838e-99/39S ribosomal protein L40, mitochondrial precursor [Mus musculus]" 94061 2322.06 14.72666667 12.77666667 -0.204919421 Down 0.366269886 Mrpl1 mitochondrial ribosomal protein L1 K02863|1|6e-164|581|mmu:94061|large subunit ribosomal protein L1 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0010467//gene expression "gi|84875528|ref|NP_444388.2|/4.93872e-163/39S ribosomal protein L1, mitochondrial isoform 1 [Mus musculus]" 70285 1307.46 10.6 12.25666667 0.209502411 Up 0.3651416 Rpf1 ribosome production factor 1 homolog K14846|1|3e-173|610|mmu:70285|ribosome production factor 1 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0003723//RNA binding GO:0042254//ribosome biogenesis;GO:0042254//ribosome biogenesis gi|169790907|ref|NP_081647.2|/2.92485e-172/ribosome production factor 1 isoform 2 [Mus musculus] 54127 328 284.63 315.7333333 0.14961885 Up 0.363420964 Rps28 ribosomal protein S28 K02979|1|6e-25|114|amj:106739155|small subunit ribosomal protein S28e GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0042254//ribosome biogenesis;GO:0006613//cotranslational protein targeting to membrane gi|470602254|ref|XP_004312818.1|/4.92463e-26/PREDICTED: 40S ribosomal protein S28 [Tursiops truncatus] 20005 737 212.4633333 234.99 0.14538548 Up 0.362038813 Rpl9 ribosomal protein L9 K02940|1|2e-102|373|cjc:100388301|large subunit ribosomal protein L9e GO:0031981//nuclear lumen;GO:0015934//large ribosomal subunit GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|675649807|ref|XP_002745952.2|/1.75642e-101/PREDICTED: 60S ribosomal protein L9 [Callithrix jacchus] 74778 1965 27.72666667 31.14333333 0.167649183 Up 0.360995148 Rrp7a ribosomal RNA processing 7 homolog A (S. cerevisiae) K14545|1|6e-138|493|mmu:74778|ribosomal RNA-processing protein 7 - GO:0003676//nucleic acid binding - gi|257467556|ref|NP_083377.3|/5.33593e-137/ribosomal RNA-processing protein 7 homolog A [Mus musculus] 18114 2008 61.06333333 67.53333333 0.145293423 Up 0.35051149 Rrp1 ribosomal RNA processing 1 homolog (S. cerevisiae) K14849|1|1e-122|443|mmu:18114|ribosomal RNA-processing protein 1 GO:0030684//preribosome;GO:0031981//nuclear lumen - GO:0042254//ribosome biogenesis "gi|148699789|gb|EDL31736.1|/8.51609e-122/novel nuclear protein 1, isoform CRA_d [Mus musculus]" 20091 960 294.04 324.9966667 0.144412494 Up 0.347305277 Rps3a1 ribosomal protein S3A1 K02984|1|2e-142|507|mmu:20091|small subunit ribosomal protein S3Ae GO:0031981//nuclear lumen;GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0003676//nucleic acid binding GO:0006412//translation;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0012502//induction of programmed cell death;GO:0048869//cellular developmental process;GO:0006613//cotranslational protein targeting to membrane gi|254553321|ref|NP_058655.3|/1.28271e-141/40S ribosomal protein S3a [Mus musculus] 229503 2847 9.423333333 10.82666667 0.200279749 Up 0.344446952 Rrnad1 ribosomal RNA adenine dimethylase domain containing 1 K02895|1|1e-38|164|mmu:67707|large subunit ribosomal protein L24 GO:0031224//intrinsic component of membrane GO:0008170//N-methyltransferase activity - gi|260166680|ref|NP_705790.3|/0/protein RRNAD1 [Mus musculus] 67212 964.55 51.71333333 56.92666667 0.138568324 Up 0.33237429 Mrpl55 mitochondrial ribosomal protein L55 K17436|1|2e-59|231|mmu:67212|large subunit ribosomal protein L55 GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle - - "gi|695917211|ref|NP_001289263.1|/1.24075e-62/39S ribosomal protein L55, mitochondrial isoform 1 [Mus musculus]" 76808 1291 377.45 414.1 0.133693656 Up 0.331001542 Rpl18a ribosomal protein L18A K02882|1|3e-101|371|rno:290641|large subunit ribosomal protein L18Ae GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane "gi|675970145|pdb|4W20|S/7.08362e-102/Chain S, Structure Of The Mammalian 60s ribosomal Subunit (this Entry Contains The Large ribosomal Proteins)" 20084 524 249.6433333 272.88 0.12839828 Up 0.329619391 Rps18 ribosomal protein S18 K02964|1|8e-76|284|nle:100580186|small subunit ribosomal protein S18e - - - gi|332245592|ref|XP_003271942.1|/5.73641e-75/PREDICTED: 40S ribosomal protein S18 [Nomascus leucogenys] 66230 738 39.03333333 43.14 0.144319506 Up 0.327607281 Mrps28 mitochondrial ribosomal protein S28 K17407|1|2e-100|367|mmu:66230|small subunit ribosomal protein S28 GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle - - "gi|254587936|ref|NP_079710.3|/1.25874e-99/28S ribosomal protein S28, mitochondrial [Mus musculus]" 18120 1722 23.51 26.02666667 0.146716013 Up 0.326516605 Mrpl49 mitochondrial ribosomal protein L49 K17430|1|2e-90|335|mmu:18120|large subunit ribosomal protein L49 GO:0000313;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005198//structural molecule activity GO:0010467//gene expression gi|148701250|gb|EDL33197.1|/2.05441e-89/mCG11737 [Mus musculus] 68565 864 105.8566667 115.61 0.127154062 Up 0.324438678 Mrps18a mitochondrial ribosomal protein S18A K02963|1|8e-116|418|mmu:68565|small subunit ribosomal protein S18 GO:0000314//organellar small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression "gi|17505206|ref|NP_081044.1|/6.5062e-115/28S ribosomal protein S18a, mitochondrial precursor [Mus musculus]" 67427 3446 20.25333333 22.52666667 0.153474481 Up 0.322360751 Rps20 ribosomal protein S20 K02969|1|2e-60|237|ecb:100053081|small subunit ribosomal protein S20e - - - - 20112 5435 14.00333333 15.67 0.162234895 Up 0.319032307 Rps6ka2 "ribosomal protein S6 kinase, polypeptide 2" K04373|1|0.0|1398|mmu:20112|p90 ribosomal S6 kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0030529//intracellular ribonucleoprotein complex GO:0032550;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity GO:0003006//developmental process involved in reproduction;GO:0008283//cell proliferation;GO:0016485//protein processing;GO:0006468//protein phosphorylation;GO:0051726//regulation of cell cycle;GO:0007126//meiotic nuclear division;GO:0010658;GO:0044767//single-organism developmental process;GO:0001976//neurological system process involved in regulation of systemic arterial blood pressure;GO:0009743//response to carbohydrate;GO:0003015//heart process;GO:0035556//intracellular signal transduction gi|6755374|ref|NP_035429.1|/0/ribosomal protein S6 kinase alpha-2 [Mus musculus] 57294 372.08 419.6833333 456.47 0.121218876 Up 0.313729362 Rps27 ribosomal protein S27 K02978|1|1e-38|160|mcf:102116449|small subunit ribosomal protein S27e GO:0043231//intracellular membrane-bounded organelle;GO:0015935//small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0015935//small ribosomal subunit GO:0046914//transition metal ion binding;GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding GO:0006412//translation;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0007067//mitotic nuclear division;GO:0006613//cotranslational protein targeting to membrane;GO:0006412//translation;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0007067//mitotic nuclear division;GO:0006613//cotranslational protein targeting to membrane gi|505851583|ref|XP_004619237.1|/1.58623e-36/PREDICTED: 40S ribosomal protein S27 [Sorex araneus] 26961 862 363.66 394.0833333 0.115910488 Up 0.31328745 Rpl8 ribosomal protein L8 K02938|1|6e-141|502|pale:102894746|large subunit ribosomal protein L8e GO:0015934//large ribosomal subunit GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|533164489|ref|XP_005395995.1|/2.62317e-140/PREDICTED: 60S ribosomal protein L8 [Chinchilla lanigera] 19988 1282 258.6733333 281.3266667 0.121114977 Up 0.312450637 Rpl6 ribosomal protein L6 K02934|1|3e-123|444|mmu:19988|large subunit ribosomal protein L6e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression gi|84662736|ref|NP_035420.2|/2.09574e-122/60S ribosomal protein L6 [Mus musculus] 94067 1213 45.44 41.56333333 -0.128651473 Down 0.311783068 Mrpl43 mitochondrial ribosomal protein L43 K17424|1|1e-77|292|mmu:94067|large subunit ribosomal protein L43 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression "gi|50401658|sp|Q99N89.1|RM43_MOUSE/2.58994e-85/RecName: Full=39S ribosomal protein L43, mitochondrial; Short=L43mt; Short=MRP-L43; AltName: Full=Mitochondrial ribosomal protein bMRP36a; Flags: Precursor" 65019 1064 204.2433333 221.3333333 0.115931752 Up 0.311294144 Rpl23 ribosomal protein L23 K02894|1|1e-70|269|ocu:100008824|large subunit ribosomal protein L23e GO:0031981//nuclear lumen;GO:0015934//large ribosomal subunit GO:0005488//binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0006606//protein import into nucleus;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|635092783|ref|XP_008011089.1|/8.21044e-71/PREDICTED: 60S ribosomal protein L23 [Chlorocebus sabaeus] 81910 5174.52 21.24666667 23.47666667 0.143991064 Up 0.309996615 Rrbp1 ribosome binding protein 1 K14000|1|0.0|1211|mmu:81910|ribosome-binding protein 1 - - - - 66480 1857 127.8533333 138.77 0.118205938 Up 0.308746098 Rpl15 ribosomal protein L15 K02877|1|3e-103|378|gja:107118857|large subunit ribosomal protein L15e GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|296490452|tpg|DAA32565.1|/2.33471e-102/TPA: ribosomal protein L15-like [Bos taurus] 629750 683 0.613333333 0.32 -0.938599455 Down 0.307693031 Gm11517 ubiquitin A-52 residue ribosomal protein fusion product 1 pseudogene K02927|1|7e-66|252|xtr:448705|large subunit ribosomal protein L40e - - - - 20088 845.44 457.41 492.8033333 0.107524108 Up 0.295723796 Rps24 ribosomal protein S24 K02974|1|5e-50|200|mze:101482129|small subunit ribosomal protein S24e GO:0031981//nuclear lumen;GO:0015935//small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0015935//small ribosomal subunit "GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0036094//small molecule binding;GO:0008135//translation factor activity, RNA binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0036094//small molecule binding;GO:0008135//translation factor activity, RNA binding" GO:0006412//translation;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0030490//maturation of SSU-rRNA;GO:0048872//homeostasis of number of cells;GO:0006613//cotranslational protein targeting to membrane;GO:0006412//translation;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0048872//homeostasis of number of cells;GO:0006613//cotranslational protein targeting to membrane;GO:0042254//ribosome biogenesis "gi|148669490|gb|EDL01437.1|/6.09094e-65/mCG7861, isoform CRA_b, partial [Mus musculus]" 665562 484 243.1433333 263.1333333 0.113986983 Up 0.29432284 Rpl31-ps12 "ribosomal protein L31, pseudogene 1 2" K02910|1|5e-64|244|mmu:665562|large subunit ribosomal protein L31e - - - - 19946 535.73 220.8666667 237.5633333 0.105136478 Up 0.293664673 Rpl30 ribosomal protein L30 K02908|1|1e-59|230|pale:102897778|large subunit ribosomal protein L30e GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|664777237|ref|XP_008507911.1|/4.16582e-60/PREDICTED: 60S ribosomal protein L30-like [Equus przewalskii] 57808 505.41 191.83 206.6366667 0.107267917 Up 0.293015909 Rpl35a ribosomal protein L35A K02917|1|2e-59|230|ocu:100343484|large subunit ribosomal protein L35Ae GO:0043231//intracellular membrane-bounded organelle;GO:0015934//large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0015934//large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0015934//large ribosomal subunit GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0042254//ribosome biogenesis;GO:0006613//cotranslational protein targeting to membrane;GO:0042254//ribosome biogenesis;GO:0010467//gene expression;GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0042254//ribosome biogenesis;GO:0006613//cotranslational protein targeting to membrane "gi|148700328|gb|EDL32275.1|/3.21403e-67/mCG1723, partial [Mus musculus]" 664903 697 27.57333333 29.93666667 0.118639907 Up 0.285531611 Rps15a-ps4 "ribosomal protein S15A, pseudogene 4" K02957|1|3e-69|263|cjc:100394618|small subunit ribosomal protein S15Ae - - - - 50529 1354 62.36666667 67.53 0.114753405 Up 0.285136711 Mrps7 mitchondrial ribosomal protein S7 K02992|1|4e-132|473|mmu:50529|small subunit ribosomal protein S7 GO:0043231//intracellular membrane-bounded organelle;GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression gi|74187439|dbj|BAE36686.1|/3.5003e-131/unnamed protein product [Mus musculus] 19791 1870 0.01 0.136666667 3.772589504 Up 0.284497349 Rn18s 18S ribosomal RNA K05692|1|3e-16|89.7|ptr:746570|actin beta/gamma 1 - - - gi|296473176|tpg|DAA15291.1|/3.58406e-73/TPA: hypothetical protein BOS_23236 [Bos taurus] 20054 522 863.4 927.13 0.102742552 Up 0.279429463 Rps15 ribosomal protein S15 K02958|1|9e-49|194|oaa:100082820|small subunit ribosomal protein S15e - - - "gi|620981188|ref|XP_001513459.3|/3.03998e-47/PREDICTED: 40S ribosomal protein S15, partial [Ornithorhynchus anatinus]" 56040 468 420.0766667 450.07 0.09949675 Up 0.278395201 Rplp1 "ribosomal protein, large, P1" K02942|1|2e-32|139|myb:102248128|large subunit ribosomal protein LP1 GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|755472674|ref|XP_011250079.1|/2.7653e-32/PREDICTED: 60S acidic ribosomal protein P1-like [Mus musculus] 19934 2204.76 36.67333333 39.69333333 0.114165319 Up 0.276467712 Rpl22 ribosomal protein L22 K02891|1|5e-37|158|gja:107126277|large subunit ribosomal protein L22e GO:0005840//ribosome;GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0005539//glycosaminoglycan binding;GO:0005198//structural molecule activity;GO:0005539//glycosaminoglycan binding;GO:0005198//structural molecule activity GO:0009987//cellular process;GO:0030217//T cell differentiation;GO:0010467//gene expression;GO:0030217//T cell differentiation;GO:0010467//gene expression gi|459683845|ref|NP_001264042.1|/5.01388e-51/60S ribosomal protein L22 isoform b [Mus musculus] 66497 1171 39.39666667 36.45666667 -0.111890911 Down 0.275969386 Cmss1 cms small ribosomal subunit 1 K14784|1|1e-69|266|dre:450027|protein CMS1 - "GO:0032550;GO:0042623//ATPase activity, coupled" - gi|12860412|dbj|BAB31948.1|/3.44115e-137/unnamed protein product [Mus musculus] 107732 1682 37.54666667 40.44 0.107098164 Up 0.275706119 Mrpl10 mitochondrial ribosomal protein L10 K02864|1|7e-121|436|mmu:107732|large subunit ribosomal protein L10 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression;GO:0022613//ribonucleoprotein complex biogenesis "gi|13385658|ref|NP_080430.1|/6.36526e-120/39S ribosomal protein L10, mitochondrial precursor [Mus musculus]" 67281 867 121.3033333 130.2866667 0.103070253 Up 0.273929068 Rpl37 ribosomal protein L37 K02922|1|7e-48|192|pale:102886771|large subunit ribosomal protein L37e GO:0015934//large ribosomal subunit GO:0043169//cation binding;GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|594059539|ref|XP_006080949.1|/1.5488e-47/PREDICTED: LOW QUALITY PROTEIN: ribosomal protein L37 [Bubalus bubalis] 52856 1553.41 18.53 20.17 0.122348203 Up 0.273806837 Mtg2 mitochondrial ribosome associated GTPase 2 K03979|1|0.0|699|mmu:52856|GTPase [EC:3.6.5.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0046872//metal ion binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0046872//metal ion binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0046872//metal ion binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 - gi|568920339|ref|XP_006500735.1|/0/PREDICTED: mitochondrial ribosome-associated GTPase 2 isoform X2 [Mus musculus] 14548 1052.51 35.78666667 33.19333333 -0.108528656 Down 0.273515363 Mrps33 mitochondrial ribosomal protein S33 K17411|1|4e-41|171|mmu:14548|small subunit ribosomal protein S33 - - - - 66163 1312 95.35 102.3133333 0.101689324 Up 0.272321261 Mrpl4 mitochondrial ribosomal protein L4 K02926|1|2e-158|560|mmu:66163|large subunit ribosomal protein L4 GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression "gi|22478084|gb|AAH37064.1|/9.01212e-161/Mrpl4 protein, partial [Mus musculus]" 67941 519 31.50333333 33.89333333 0.105497043 Up 0.271644289 Rps27l ribosomal protein S27-like K02978|1|2e-38|160|cfa:610569|small subunit ribosomal protein S27e - - - - 353242 992 27.35333333 29.59333333 0.113555554 Up 0.270027079 Mrpl21 mitochondrial ribosomal protein L21 K02888|1|4e-103|376|mmu:353242|large subunit ribosomal protein L21 GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0010467//gene expression "gi|31982032|ref|NP_758456.2|/3.60677e-102/39S ribosomal protein L21, mitochondrial [Mus musculus]" 67223 1228 3.943333333 3.423333333 -0.204013892 Down 0.265194253 Rrp15 ribosomal RNA processing 15 homolog (S. cerevisiae) - GO:0043231//intracellular membrane-bounded organelle - - "gi|148681111|gb|EDL13058.1|/1.28703e-89/RIKEN cDNA 2810430M08, isoform CRA_b [Mus musculus]" 212508 1595 13.77333333 15.00333333 0.123405311 Up 0.26305051 Mtg1 mitochondrial ribosome-associated GTPase 1 K19828|1|0.0|660|mmu:212508|mitochondrial GTPase 1 GO:0043231//intracellular membrane-bounded organelle - - gi|188528646|ref|NP_955005.2|/0/mitochondrial ribosome-associated GTPase 1 [Mus musculus] 100042049 810 0.01 0.123333333 3.624490865 Up 0.262984693 Gm15421 ribosomal protein L22 like 1 pseudogene K02891|1|6e-52|206|cge:100750612|large subunit ribosomal protein L22e GO:0030529//intracellular ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression gi|148671237|gb|EDL03184.1|/5.31568e-52/mCG6454 [Mus musculus] 74600 899 21.55333333 19.92 -0.113693359 Down 0.260972583 Mrpl47 mitochondrial ribosomal protein L47 K17428|1|1e-145|518|mmu:74600|large subunit ribosomal protein L47 GO:0000313;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression "gi|29826332|ref|NP_083293.1|/8.44692e-145/39S ribosomal protein L47, mitochondrial [Mus musculus]" 27395 2690.72 35.22666667 37.86 0.104006445 Up 0.260286209 Mrpl15 mitochondrial ribosomal protein L15 K02876|1|2e-86|322|rno:297799|large subunit ribosomal protein L15 GO:0043231//intracellular membrane-bounded organelle;GO:0044391//ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0044391//ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0044391//ribosomal subunit GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0010467//gene expression;GO:0010467//gene expression "gi|33468983|ref|NP_079576.1|/2.89755e-95/39S ribosomal protein L15, mitochondrial isoform 2 precursor [Mus musculus]" 11837 1360 617.5766667 659.3166667 0.094353306 Up 0.259966528 Rplp0 "ribosomal protein, large, P0" K02941|1|8e-142|506|mmu:11837|large subunit ribosomal protein LP0 GO:0043231//intracellular membrane-bounded organelle;GO:0015934//large ribosomal subunit - GO:0022613//ribonucleoprotein complex biogenesis;GO:0006412//translation;GO:0070670//response to interleukin-4 gi|6671569|ref|NP_031501.1|/6.40587e-141/60S acidic ribosomal protein P0 [Mus musculus] 19943 496 582.7833333 621.5933333 0.093011412 Up 0.259919516 Rpl28 ribosomal protein L28 K02903|1|4e-61|235|xla:100505437|large subunit ribosomal protein L28e GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|674075120|ref|XP_008844880.1|/2.4938e-60/PREDICTED: 60S ribosomal protein L28 [Nannospalax galili] 19899 708 332.32 353.43 0.088851383 Up 0.258941668 Rpl18 ribosomal protein L18 K02883|1|2e-95|350|cge:100774500|large subunit ribosomal protein L18e GO:0015934//large ribosomal subunit - GO:0010467//gene expression gi|13592057|ref|NP_112364.1|/1.92924e-94/60S ribosomal protein L18 [Rattus norvegicus] 66475 572 300.4633333 318.7966667 0.0854476 Up 0.258574975 Rps23 ribosomal protein S23 K02973|1|8e-87|321|phd:102325901|small subunit ribosomal protein S23e GO:0015935//small ribosomal subunit GO:0005488//binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|556727449|ref|XP_005959475.1|/5.58397e-86/PREDICTED: uncharacterized protein LOC102325901 [Pantholops hodgsonii] 110651 7320 3.276666667 2.823333333 -0.214829447 Down 0.257211629 Rps6ka3 ribosomal protein S6 kinase polypeptide 3 K04373|1|0.0|1428|lve:103087256|p90 ribosomal S6 kinase [EC:2.7.11.1] - - - - 236598 4730 1.946666667 1.6 -0.282933963 Down 0.256384219 Rn28s1 28S ribosomal RNA "K04257|1|5e-18|97.1|ola:101174077|olfactory receptor;K12176|2|9e-11|47.8|tup:102492997|COP9 signalosome complex subunit 2;K19720|4|5e-09|67.0|fca:105260247|collagen, type III, alpha" - - - gi|678336953|emb|CDW75723.1|/1.71451e-96/UNKNOWN [Stylonychia lemnae] 625347 1001 0.056666667 0.21 1.889817082 Up 0.255697845 Gm6578 mitochondrial ribosomal protein L32 pseudogene K02911|1|2e-84|268|rno:291206|large subunit ribosomal protein L32 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression "gi|157820155|ref|NP_001099586.1|/1.75486e-83/39S ribosomal protein L32, mitochondrial precursor [Rattus norvegicus] " 66128 715.2 134.77 126.4933333 -0.091438035 Down 0.255255933 Mrps36 mitochondrial ribosomal protein S36 K17414|1|5e-49|196|mmu:66128|small subunit ribosomal protein S36 GO:0000314//organellar small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0000314//organellar small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0010467//gene expression "gi|148668476|gb|EDL00795.1|/5.90646e-59/mCG116118, isoform CRA_e, partial [Mus musculus]" 68731 1361 29.19333333 31.25333333 0.09837112 Up 0.255002069 Rbfa ribosome binding factor A - GO:0043231//intracellular membrane-bounded organelle - GO:0042254//ribosome biogenesis gi|39794027|gb|AAH64066.1|/0/RIKEN cDNA 1110032A13 gene [Mus musculus] 66419 2882 16.43666667 17.77666667 0.113067075 Up 0.254475535 Mrpl11 mitochondrial ribosomal protein L11 K02867|1|5e-81|283|rno:293666|large subunit ribosomal protein L11 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression "gi|55742212|ref|NP_001006974.1|/4.22125e-80/39S ribosomal protein L11, mitochondrial [Rattus norvegicus]" 94065 663 97.21666667 103.4133333 0.089146634 Up 0.253572906 Mrpl34 mitochondrial ribosomal protein L34 K02914|1|4e-48|192|mmu:94065|large subunit ribosomal protein L34 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression "gi|16716449|ref|NP_444392.1|/3.35336e-47/39S ribosomal protein L34, mitochondrial [Mus musculus]" 68611 1080 94.50333333 88.55333333 -0.093818603 Down 0.253319042 Mrpl28 mitochondrial ribosomal protein L28 K02902|1|5e-149|529|mmu:68611|large subunit ribosomal protein L28 GO:0000313;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression gi|26324321|dbj|BAB22962.2|/9.37432e-155/unnamed protein product [Mus musculus] 218506 1849 25.88666667 27.81 0.103394538 Up 0.25307458 Mrps27 mitochondrial ribosomal protein S27 K17406|1|0.0|743|mmu:218506|small subunit ribosomal protein S27 - - - "gi|50980303|ref|NP_776118.2|/0/28S ribosomal protein S27, mitochondrial [Mus musculus]" 27397 6712 6.613333333 7.283333333 0.139221254 Up 0.249417052 Mrpl17 mitochondrial ribosomal protein L17 K02879|1|2e-82|311|mmu:27397|large subunit ribosomal protein L17 GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0005515//protein binding GO:0010467//gene expression "gi|13384658|ref|NP_079577.1|/1.96325e-81/39S ribosomal protein L17, mitochondrial precursor [Mus musculus]" 213895 4305 6.78 6.156666667 -0.139135813 Down 0.24451841 Bms1 "BMS1, ribosome biogenesis factor" K14569|1|0.0|2115|mmu:213895|ribosome biogenesis protein BMS1 - - - - 20111 3046.93 3.823333333 3.373333333 -0.180656101 Down 0.244104705 Rps6ka1 ribosomal protein S6 kinase polypeptide 1 K04373|1|0.0|1469|bta:533908|p90 ribosomal S6 kinase [EC:2.7.11.1] GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0005515//protein binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0005515//protein binding "GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0016049//cell growth;GO:0035733//hepatic stellate cell activation;GO:0006935//chemotaxis;GO:0030154//cell differentiation;GO:0007267//cell-cell signaling;GO:0006417//regulation of translation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006464//cellular protein modification process;GO:0000165//MAPK cascade;GO:0006355//regulation of transcription, DNA-templated;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0016049//cell growth;GO:0035733//hepatic stellate cell activation;GO:0006935//chemotaxis;GO:0030154//cell differentiation;GO:0007267//cell-cell signaling;GO:0006417//regulation of translation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006464//cellular protein modification process;GO:0000165//MAPK cascade;GO:0006355//regulation of transcription, DNA-templated" gi|550822267|ref|NP_001272435.1|/0/ribosomal protein S6 kinase alpha-1 isoform c [Mus musculus] 320119 4034 4.24 3.77 -0.169499741 Down 0.243324307 Rps6kc1 ribosomal protein S6 kinase polypeptide 1 K17927|1|2e-39|167|bom:102286466|sorting nexin-15 GO:0005768//endosome GO:0005543//phospholipid binding;GO:0016301//kinase activity;GO:0032550 GO:0044763 gi|294862300|ref|NP_848890.3|/0/ribosomal protein S6 kinase delta-1 [Mus musculus] 268449 560 689.16 729.6566667 0.082378809 Up 0.242017376 Rpl23a ribosomal protein L23A K02893|1|2e-66|253|aam:106487794|large subunit ribosomal protein L23Ae GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0015934//large ribosomal subunit GO:0003723//RNA binding;GO:0005198//structural molecule activity;GO:0036094//small molecule binding GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|351710149|gb|EHB13068.1|/4.41582e-69/60S ribosomal protein L23a [Heterocephalus glaber] 20068 489 497.0466667 470.1833333 -0.080157909 Down 0.241575464 Rps17 ribosomal protein S17 K02962|1|5e-71|268|xtr:100145026|small subunit ribosomal protein S17e - - - gi|26377673|dbj|BAC25377.1|/3.16316e-73/unnamed protein product [Mus musculus] 67270 666 432.6033333 456.2866667 0.076895715 Up 0.241387416 Mrpl42 mitochondrial ribosomal protein L42 K17423|1|2e-81|303|mmu:67270|large subunit ribosomal protein L42 GO:0000314//organellar small ribosomal subunit;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle - - "gi|13385564|ref|NP_080341.1|/1.38099e-80/39S ribosomal protein L42, mitochondrial precursor [Mus musculus]" 67891 1422 315.7466667 333.1133333 0.077245598 Up 0.240701042 Rpl4 ribosomal protein L4 K02930|1|0.0|680|fca:101080458|large subunit ribosomal protein L4e GO:0015934//large ribosomal subunit;GO:0031981//nuclear lumen GO:0005488//binding;GO:0005198//structural molecule activity GO:0010467//gene expression gi|586988825|ref|XP_003987064.2|/0/PREDICTED: 60S ribosomal protein L4 [Felis catus] 22121 1039 292.37 308.9633333 0.07964035 Up 0.240550604 Rpl13a ribosomal protein L13A K02872|1|2e-108|394|cge:100773637|large subunit ribosomal protein L13Ae GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0006412//translation;GO:0051129;GO:0034341//response to interferon-gamma gi|625263830|ref|XP_007623352.1|/1.81378e-107/PREDICTED: 60S ribosomal protein L13a isoform X2 [Cricetulus griseus] 20044 606 303.6366667 320.29 0.077032737 Up 0.240550604 Rps14 ribosomal protein S14 K02955|1|4e-74|279|tru:101075027|small subunit ribosomal protein S14e GO:0031981//nuclear lumen;GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity;GO:0003824//catalytic activity;GO:0003729//mRNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0006412//translation;GO:0022618//ribonucleoprotein complex assembly;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0030099//myeloid cell differentiation;GO:0006613//cotranslational protein targeting to membrane;GO:0006364//rRNA processing gi|859746458|ref|XP_004737878.2|/1.66424e-81/PREDICTED: 40S ribosomal protein S14 [Mustela putorius furo] 269261 643 245.4533333 260.18 0.084061307 Up 0.240127496 Rpl12 ribosomal protein L12 K02870|1|8e-105|381|bacu:103012292|large subunit ribosomal protein L12e - - - gi|803286756|ref|XP_012003022.1|/5.04994e-106/PREDICTED: 60S ribosomal protein L12 isoform X2 [Ovis aries musimon] 216767 753 35.81 33.71333333 -0.087043241 Down 0.239958253 Mrpl22 mitochondrial ribosomal protein L22 K02890|1|1e-101|371|mmu:216767|large subunit ribosomal protein L22 GO:0043231//intracellular membrane-bounded organelle;GO:0044391//ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression gi|148703828|gb|EDL35775.1|/3.72404e-110/mCG49192 [Mus musculus] 75617 701 208.7166667 220.4066667 0.078622053 Up 0.239459927 Rps25 ribosomal protein S25 K02975|1|4e-37|156|nle:100602471|small subunit ribosomal protein S25e GO:0031981//nuclear lumen;GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding GO:0006412//translation;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0006613//cotranslational protein targeting to membrane "gi|148693644|gb|EDL25591.1|/2.83468e-42/mCG10725, isoform CRA_b, partial [Mus musculus]" 97112 1739 9.02 8.28 -0.123496666 Down 0.239046222 Nmd3 NMD3 ribosome export adaptor K07562|1|0.0|1030|mmu:97112|nonsense-mediated mRNA decay protein 3 GO:0031981//nuclear lumen GO:0043021//ribonucleoprotein complex binding GO:0045184//establishment of protein localization "gi|148683547|gb|EDL15494.1|/0/NMD3 homolog (S. cerevisiae), isoform CRA_b [Mus musculus]" 73486 731 0.083333333 0.22 1.40053793 Up 0.238124788 1700084J12Rik ribosomal protein L7-like 1 pseudogene K02937|1|3e-35|132|xma:102224219|large subunit ribosomal protein L7e GO:0032991//macromolecular complex - - "gi|149069422|gb|EDM18863.1|/1.15881e-89/rCG43676, isoform CRA_a [Rattus norvegicus]" 66493 1515 110.9833333 117.6266667 0.083872125 Up 0.237203355 Mrpl51 mitochondrial ribosomal protein L51 K17432|1|5e-73|277|mmu:66493|large subunit ribosomal protein L51 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression "gi|13385050|ref|NP_079871.1|/4.29551e-72/39S ribosomal protein L51, mitochondrial precursor [Mus musculus]" 667338 611 0.01 0.096666667 3.273018494 Up 0.233188537 Gm8580 ribosomal protein L29 pseudogene K02905|1|1e-57|175|mmu:19944|large subunit ribosomal protein L29e GO:0015934//large ribosomal subunit;GO:0044425 GO:0005539//glycosaminoglycan binding GO:0007155//cell adhesion;GO:0010467//gene expression;GO:0040007//growth gi|148709224|gb|EDL41170.1|/8.11244e-57/mCG142394 [Mus musculus] 194237 4093 0.123333333 0.263333333 1.094327383 Up 0.2314679 Rimkla ribosomal modification protein rimK-like family member A K18311|1|0.0|720|mmu:194237|N-acetylaspartylglutamate/N-acetylaspartylglutamylglutamate synthase [EC:6.3.2.41 6.3.2.42] GO:0044424 "GO:0043169//cation binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0032550" GO:0036211//protein modification process "gi|148698492|gb|EDL30439.1|/0/cDNA sequence BC057371, partial [Mus musculus]" 64657 1032 20.38 19.08333333 -0.094840859 Down 0.228788221 Mrps10 mitochondrial ribosomal protein S10 K02946|1|2e-96|354|mmu:64657|small subunit ribosomal protein S10 GO:0000314//organellar small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0000314//organellar small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0000314//organellar small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression;GO:0010467//gene expression;GO:0010467//gene expression "gi|226246600|ref|NP_001139683.1|/4.12953e-96/28S ribosomal protein S10, mitochondrial isoform 2 [Mus musculus]" 66973 1073 48.08 45.59666667 -0.076508536 Down 0.22827109 Mrps18b mitochondrial ribosomal protein S18B "K16174|1|3e-118|427|mmu:66973|small subunit ribosomal protein S18b, mitochondrial" GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression "gi|23956152|ref|NP_080154.1|/2.64174e-117/28S ribosomal protein S18b, mitochondrial [Mus musculus]" 75593 785 19.61 20.87 0.089841065 Up 0.22803603 Malsu1 mitochondrial assembly of ribosomal large subunit 1 - GO:0043231//intracellular membrane-bounded organelle - GO:0010823//negative regulation of mitochondrion organization;GO:0042254//ribosome biogenesis gi|568943107|ref|XP_006506785.1|/1.08838e-123/PREDICTED: mitochondrial assembly of ribosomal large subunit protein 1 isoform X2 [Mus musculus] 224823 1212 9.256666667 8.57 -0.111197567 Down 0.226841927 Rrp36 ribosomal RNA processing 36 homolog (S. cerevisiae) K14795|1|4e-82|307|mmu:224823|ribosomal RNA-processing protein 36 GO:0031981//nuclear lumen - GO:0042254//ribosome biogenesis gi|148691573|gb|EDL23520.1|/1.10614e-85/cDNA sequence BC011248 [Mus musculus] 225215 1522 18.00333333 19.13 0.087572826 Up 0.224669976 Rsl24d1 ribosomal L24 domain containing 1 K02896|1|9e-81|303|ocu:100343236|large subunit ribosomal protein L24e GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen - GO:0022613//ribonucleoprotein complex biogenesis gi|655862719|ref|XP_002717761.2|/7.37131e-80/PREDICTED: probable ribosome biogenesis protein RLP24 [Oryctolagus cuniculus] 20104 1394 329.4133333 345.0066667 0.066725289 Up 0.22133213 Rps6 ribosomal protein S6 K02991|1|6e-118|426|fca:101098495|small subunit ribosomal protein S6e GO:0031981//nuclear lumen;GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity;GO:0019900//kinase binding GO:0000075//cell cycle checkpoint;GO:0022618//ribonucleoprotein complex assembly;GO:0006915//apoptotic process;GO:0002286//T cell activation involved in immune response;GO:0042254//ribosome biogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0000087//mitotic M phase;GO:0030217//T cell differentiation;GO:0044772//mitotic cell cycle phase transition;GO:0033500//carbohydrate homeostasis;GO:0006613//cotranslational protein targeting to membrane;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0044702//single organism reproductive process;GO:0019080;GO:0035556//intracellular signal transduction;GO:0006412//translation;GO:0030218//erythrocyte differentiation;GO:0048598//embryonic morphogenesis;GO:0043029//T cell homeostasis gi|755785705|ref|XP_003995546.2|/5.08562e-117/PREDICTED: 40S ribosomal protein S6 [Felis catus] 67025 594 346.86 331.53 -0.065214053 Down 0.221275716 Rpl11 ribosomal protein L11 K02868|1|3e-99|362|pale:102883699|large subunit ribosomal protein L11e GO:0031981//nuclear lumen;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0003723//RNA binding GO:0006412//translation;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0006613//cotranslational protein targeting to membrane;GO:0033365//protein localization to organelle;GO:0042254//ribosome biogenesis gi|725552974|ref|XP_010347552.1|/1.53312e-100/PREDICTED: 60S ribosomal protein L11 isoform X1 [Saimiri boliviensis boliviensis] 59054 1590 27.41 29.03333333 0.08300789 Up 0.220956034 Mrps30 mitochondrial ribosomal protein S30 K17409|1|0.0|739|mmu:59054|small subunit ribosomal protein S30 GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression "gi|148686412|gb|EDL18359.1|/0/mitochondrial ribosomal protein S30, partial [Mus musculus]" 66538 830 6.236666667 6.76 0.116248094 Up 0.220711572 Rps19bp1 ribosomal protein S19 binding protein 1 - GO:0031981//nuclear lumen - - gi|30424711|ref|NP_780318.1|/1.15378e-57/active regulator of SIRT1 [Mus musculus] 624713 556 0.206666667 0.09 -1.199308808 Down 0.218708865 Gm6525 ribosomal protein L36a pseudogene K02929|1|9e-61|234|ngi:103746226|large subunit ribosomal protein L44e - - - gi|589947649|ref|XP_006986494.1|/4.34256e-61/PREDICTED: 60S ribosomal protein L36a [Peromyscus maniculatus bairdii] 64656 1350.34 114.0966667 119.66 0.068684324 Up 0.218041295 Mrps23 mitochondrial ribosomal protein S23 K17402|1|5e-89|330|mmu:64656|small subunit ribosomal protein S23 GO:0005856//cytoskeleton;GO:0000314//organellar small ribosomal subunit;GO:0005635//nuclear envelope;GO:0005856//cytoskeleton;GO:0000314//organellar small ribosomal subunit;GO:0005635//nuclear envelope;GO:0005856//cytoskeleton;GO:0000314//organellar small ribosomal subunit;GO:0005635//nuclear envelope;GO:0005856//cytoskeleton;GO:0000314//organellar small ribosomal subunit;GO:0005635//nuclear envelope;GO:0005856//cytoskeleton;GO:0000314//organellar small ribosomal subunit;GO:0005635//nuclear envelope;GO:0005856//cytoskeleton;GO:0000314//organellar small ribosomal subunit;GO:0005635//nuclear envelope - GO:0010467//gene expression;GO:0010467//gene expression;GO:0010467//gene expression;GO:0010467//gene expression;GO:0010467//gene expression;GO:0010467//gene expression "gi|12805371|gb|AAH02155.1|/8.25989e-110/Mrps23 protein, partial [Mus musculus]" 121022 795 25.56333333 26.96333333 0.076922891 Up 0.217834443 Mrps6 mitochondrial ribosomal protein S6 K02990|1|9e-68|258|rno:100360017|small subunit ribosomal protein S6 GO:0043231//intracellular membrane-bounded organelle;GO:0044391//ribosomal subunit GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0010467//gene expression gi|13620887|dbj|BAB40996.1|/4.28696e-83/mitochondrial ribosomal protein S6 [Mus musculus] 70808 4136 3.993333333 4.393333333 0.137722462 Up 0.217148069 4632415L05Rik RRS1 ribosome biogenesis regulator homolog pseudogene K14852|1|1e-32|145|lve:103080814|regulator of ribosome biosynthesis GO:0043231//intracellular membrane-bounded organelle - - gi|148678817|gb|EDL10764.1|/1.10639e-39/mCG1027215 [Mus musculus] 232536 1067 77.23666667 73.51666667 -0.071214548 Down 0.215549663 Mrps35 mitochondrial ribosomal protein S35 K17413|1|0.0|645|mmu:232536|small subunit ribosomal protein S35 GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle - - "gi|148235701|ref|NP_663548.2|/0/28S ribosomal protein S35, mitochondrial [Mus musculus] " 72462 4714.66 2.856666667 2.536666667 -0.171398751 Down 0.214712851 Rrp1b ribosomal RNA processing 1 homolog B (S. cerevisiae) K14849|1|0.0|1284|mmu:72462|ribosomal RNA-processing protein 1 GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0030684//preribosome;GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0030684//preribosome GO:0005488//binding;GO:0005488//binding GO:0042254//ribosome biogenesis;GO:0010921//regulation of phosphatase activity;GO:0042254//ribosome biogenesis;GO:0010921//regulation of phosphatase activity gi|254911009|ref|NP_082520.2|/0/ribosomal RNA processing protein 1 homolog B isoform 1 [Mus musculus] 66448 665 65.94 62.61 -0.074760786 Down 0.214684644 Mrpl20 mitochondrial ribosomal protein L20 K02887|1|1e-70|268|mmu:66448|large subunit ribosomal protein L20 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding GO:0010467//gene expression "gi|20270194|ref|NP_079846.1|/8.29999e-70/39S ribosomal protein L20, mitochondrial precursor [Mus musculus]" 67840 2321 8.933333333 9.553333333 0.096805609 Up 0.214129903 Mrpl57 mitochondrial ribosomal protein L57 - GO:0000313;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression "gi|13385888|ref|NP_080677.1|/4.98276e-52/ribosomal protein 63, mitochondrial [Mus musculus]" 66242 566 64.63666667 61.49333333 -0.071922788 Down 0.214101696 Mrps16 mitochondrial ribosomal protein S16 K02959|1|4e-59|229|mmu:66242|small subunit ribosomal protein S16 GO:0000314//organellar small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005198//structural molecule activity GO:0010467//gene expression "gi|13384844|ref|NP_079716.1|/2.78654e-58/28S ribosomal protein S16, mitochondrial precursor [Mus musculus]" 667423 666 0.28 0.15 -0.900464326 Down 0.213358908 Gm8624 ribosomal protein S23 pseudogene K02973|1|6e-53|115|hst:105184477|small subunit ribosomal protein S23e - - - - 24030 684 47.75666667 50.26666667 0.07389988 Up 0.212023769 Mrps12 mitochondrial ribosomal protein S12 K02950|1|4e-75|283|mmu:24030|small subunit ribosomal protein S12 GO:0043231//intracellular membrane-bounded organelle;GO:0044391//ribosomal subunit - GO:0010467//gene expression "gi|6755360|ref|NP_036015.1|/2.66222e-74/28S ribosomal protein S12, mitochondrial precursor [Mus musculus]" 68499 620 48.28333333 46.15333333 -0.065090431 Down 0.209992854 Mrpl53 mitochondrial ribosomal protein L53 K17434|1|3e-60|233|mmu:68499|large subunit ribosomal protein L53 GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle - - "gi|21313040|ref|NP_081020.1|/1.8974e-59/39S ribosomal protein L53, mitochondrial [Mus musculus]" 21453 4605.34 8.733333333 8.17 -0.096196328 Down 0.209485125 Tcof1 treacle ribosome biogenesis factor 1 K14562|1|0.0|1375|mmu:21453|Treacher Collins syndrome protein - - GO:0006360//transcription from RNA polymerase I promoter;GO:0006360//transcription from RNA polymerase I promoter "gi|148677856|gb|EDL09803.1|/0/Treacher Collins Franceschetti syndrome 1, homolog, isoform CRA_f [Mus musculus]" 100861531 13400 0.06 0.16 1.415037499 Up 0.20405995 Rn45s 45S pre-ribosomal RNA "K04257|1|1e-17|97.1|ola:101174077|olfactory receptor;K05692|2|2e-15|89.7|ptr:746570|actin beta/gamma 1;K19720|3|2e-08|67.0|fca:105260247|collagen, type III, alpha;K12176|5|6e-08|45.1|tup:102492997|COP9 signalosome complex subunit 2" - - - gi|954381024|gb|KRY44974.1|/0/hypothetical protein T03_16985 [Trichinella britovi] 16898 1005 803.1933333 834.8733333 0.055810034 Up 0.203091504 Rps2 ribosomal protein S2 K02981|1|8e-135|482|pale:102882402|small subunit ribosomal protein S2e GO:0015935//small ribosomal subunit;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0019838//growth factor binding;GO:0005198//structural molecule activity GO:0006413//translational initiation;GO:0070670//response to interleukin-4 "gi|148706863|gb|EDL38810.1|/2.06751e-137/mCG122489, isoform CRA_a, partial [Mus musculus]" 19921 758.32 480.2633333 500.44 0.059371441 Up 0.202724811 Rpl19 ribosomal protein L19 K02885|1|1e-69|255|ptg:102958746|large subunit ribosomal protein L19e GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|795356643|ref|XP_011785310.1|/9.42427e-70/PREDICTED: 60S ribosomal protein L19 isoform X7 [Colobus angolensis palliatus] 27370 457 402.6333333 420.7733333 0.063576661 Up 0.20260258 Rps26 ribosomal protein S26 K02976|1|2e-41|169|rno:100360508|small subunit ribosomal protein S26e - - - gi|564315719|ref|XP_003752685.2|/1.57638e-40/PREDICTED: 40S ribosomal protein S26-like [Rattus norvegicus] 56613 3152 9.123333333 9.703333333 0.088919405 Up 0.201558915 Rps6ka4 "ribosomal protein S6 kinase, polypeptide 4" K16510|1|0.0|1432|mmu:56613|ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1] GO:0031981//nuclear lumen;GO:0030529//intracellular ribonucleoprotein complex GO:0051019//mitogen-activated protein kinase binding;GO:0032550;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity GO:0001934//positive regulation of protein phosphorylation;GO:0035404//histone-serine phosphorylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0019221//cytokine-mediated signaling pathway;GO:0001816//cytokine production;GO:0006935//chemotaxis;GO:0006952//defense response;GO:0016573//histone acetylation;GO:0035556//intracellular signal transduction gi|485464582|ref|NP_064308.2|/0/ribosomal protein S6 kinase alpha-4 [Mus musculus] 107734 691 223.1233333 214.2 -0.058882913 Down 0.201060589 Mrpl30 mitochondrial ribosomal protein L30 K02907|1|4e-90|332|mmu:107734|large subunit ribosomal protein L30 GO:0000313;GO:0043231//intracellular membrane-bounded organelle - - "gi|148682587|gb|EDL14534.1|/2.52887e-96/mitochondrial ribosomal protein L30, isoform CRA_b, partial [Mus musculus]" 19933 1871 189.7433333 198.3233333 0.063805228 Up 0.20098537 Rpl21 ribosomal protein L21 K02889|1|4e-89|331|myb:102263018|large subunit ribosomal protein L21e GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|31560385|ref|NP_062621.2|/3.30779e-88/60S ribosomal protein L21 [Mus musculus] 56282 963 200.5133333 208.4 0.055657104 Up 0.20075031 Mrpl12 mitochondrial ribosomal protein L12 K02935|1|2e-65|251|mmu:56282|large subunit ribosomal protein L7/L12 GO:0043231//intracellular membrane-bounded organelle;GO:0000315//organellar large ribosomal subunit - "GO:0000959//mitochondrial RNA metabolic process;GO:0006351//transcription, DNA-templated" "gi|148702808|gb|EDL34755.1|/3.81083e-69/mitochondrial ribosomal protein L12, partial [Mus musculus]" 67115 935 139.0366667 144.87 0.05929347 Up 0.199894693 Rpl14 ribosomal protein L14 K02875|1|1e-72|275|mmu:67115|large subunit ribosomal protein L14e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0042254//ribosome biogenesis;GO:0010467//gene expression gi|148690892|gb|EDL22839.1|/1.02604e-71/mCG132493 [Mus musculus] 77721 1448 39.86 38.24 -0.059859187 Down 0.19077438 Mrps5 mitochondrial ribosomal protein S5 K02988|1|0.0|798|mmu:77721|small subunit ribosomal protein S5 GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression "gi|17157985|ref|NP_084239.1|/0/28S ribosomal protein S5, mitochondrial [Mus musculus]" 623169 1356 0.133333333 0.233333333 0.807354922 Up 0.188320358 Gm6402 ribosomal protein S17 pseudogene K02962|1|8e-62|240|xtr:100145026|small subunit ribosomal protein S17e - - - gi|26377673|dbj|BAC25377.1|/6.31489e-64/unnamed protein product [Mus musculus] 69902 1242 13.75666667 13.08666667 -0.072033266 Down 0.186759562 Mrto4 "mRNA turnover 4, ribosome maturation factor" K14815|1|7e-121|436|mmu:69902|mRNA turnover protein 4 GO:0005635//nuclear envelope;GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen;GO:0005635//nuclear envelope;GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen - GO:0022613//ribonucleoprotein complex biogenesis;GO:0022613//ribonucleoprotein complex biogenesis gi|595763400|ref|NP_001277739.1|/5.83228e-122/mRNA turnover protein 4 homolog isoform 1 [Mus musculus] 22186 524 942.7166667 973.5566667 0.04644072 Up 0.183901237 Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 K02927|1|9e-75|280|myb:102242964|large subunit ribosomal protein L40e GO:0030139//endocytic vesicle;GO:0031090//organelle membrane;GO:0031981//nuclear lumen;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0005488//binding "GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006915//apoptotic process;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0050851//antigen receptor-mediated signaling pathway;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0006259//DNA metabolic process;GO:0001666//response to hypoxia;GO:0044772//mitotic cell cycle phase transition;GO:0051320;GO:0051403//stress-activated MAPK cascade;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006613//cotranslational protein targeting to membrane;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0002753;GO:0019080;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006412//translation;GO:0001818//negative regulation of cytokine production;GO:0051318;GO:0006468//protein phosphorylation" gi|946770170|ref|XP_005869533.2|/6.34235e-74/PREDICTED: ubiquitin-60S ribosomal protein L40 [Myotis brandtii] 19944 802.75 363.6366667 376.1233333 0.04870813 Up 0.183036218 Rpl29 ribosomal protein L29 K02905|1|7e-67|256|mmu:19944|large subunit ribosomal protein L29e - - - - 20090 449 334.7333333 346.5566667 0.050079047 Up 0.182951597 Rps29 ribosomal protein S29 K02980|1|4e-29|128|amj:102564402|small subunit ribosomal protein S29e GO:0015935//small ribosomal subunit GO:0046914//transition metal ion binding;GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding;GO:0003824//catalytic activity GO:0072331//signal transduction by p53 class mediator;GO:0006412//translation;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0030218//erythrocyte differentiation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0006613//cotranslational protein targeting to membrane;GO:0007049//cell cycle gi|759100021|ref|XP_011375277.1|/6.04975e-32/PREDICTED: LOW QUALITY PROTEIN: 40S ribosomal protein S29 [Pteropus vampyrus] 19989 937 297.8766667 307.44 0.045589763 Up 0.182575501 Rpl7 ribosomal protein L7 K02937|1|2e-143|510|mmu:19989|large subunit ribosomal protein L7e GO:0015934//large ribosomal subunit GO:0003723//RNA binding;GO:0042802//identical protein binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0042254//ribosome biogenesis;GO:0006613//cotranslational protein targeting to membrane gi|31981515|ref|NP_035421.2|/1.90621e-142/60S ribosomal protein L7 [Mus musculus] 101867 2880.97 5.923333333 6.283333333 0.085120842 Up 0.181682275 Rrp8 "ribosomal RNA processing 8, methyltransferase, homolog (yeast)" K14850|1|0.0|872|mmu:101867|ribosomal RNA-processing protein 8 [EC:2.1.1.287] GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0043234//protein complex;GO:0000792//heterochromatin;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0043234//protein complex;GO:0000792//heterochromatin GO:0042393//histone binding;GO:0016741;GO:0042393//histone binding;GO:0016741 GO:0045990//carbon catabolite regulation of transcription;GO:0072331//signal transduction by p53 class mediator;GO:0006342//chromatin silencing;GO:0007050//cell cycle arrest;GO:0009267//cellular response to starvation;GO:0042254//ribosome biogenesis;GO:0006325//chromatin organization;GO:0045990//carbon catabolite regulation of transcription;GO:0072331//signal transduction by p53 class mediator;GO:0006342//chromatin silencing;GO:0007050//cell cycle arrest;GO:0009267//cellular response to starvation;GO:0042254//ribosome biogenesis;GO:0006325//chromatin organization gi|20270198|ref|NP_080173.1|/0/ribosomal RNA-processing protein 8 isoform 2 [Mus musculus] 100503670 2036 131.7733333 136.7466667 0.053447221 Up 0.181099327 Rpl5 ribosomal protein L5 K02932|1|9e-161|569|tup:102471744|large subunit ribosomal protein L5e GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0015934//large ribosomal subunit GO:0019843//rRNA binding;GO:0005198//structural molecule activity GO:0010035//response to inorganic substance;GO:0042254//ribosome biogenesis;GO:0010467//gene expression;GO:0010921//regulation of phosphatase activity "gi|947197573|ref|XP_014442064.1|/8.01529e-160/PREDICTED: 60S ribosomal protein L5, partial [Tupaia chinensis]" 78294 729.89 123.1233333 127.7766667 0.053520214 Up 0.180911279 Rps27a ribosomal protein S27A K02977|1|5e-70|266|oas:100135694|small subunit ribosomal protein S27Ae GO:0030139//endocytic vesicle;GO:0031090//organelle membrane;GO:0031981//nuclear lumen;GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity;GO:0043169//cation binding "GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006915//apoptotic process;GO:0006301//postreplication repair;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0050851//antigen receptor-mediated signaling pathway;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0001666//response to hypoxia;GO:0044772//mitotic cell cycle phase transition;GO:0051320;GO:0051403//stress-activated MAPK cascade;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006613//cotranslational protein targeting to membrane;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0002753;GO:0019080;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0000187//activation of MAPK activity;GO:0006412//translation;GO:0001818//negative regulation of cytokine production;GO:0051318" gi|803037831|ref|XP_004005993.2|/5.05311e-66/PREDICTED: ubiquitin-40S ribosomal protein S27a [Ovis aries] 382038 5773 1.68 1.503333333 -0.1602963 Down 0.175645944 Urb2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) K14862|1|0.0|2786|mmu:382038|nucleolar pre-ribosomal-associated protein 2 - - - gi|71274162|ref|NP_001025047.1|/0/unhealthy ribosome biogenesis protein 2 homolog [Mus musculus] 78523 1601 38.29 39.76666667 0.054591977 Up 0.174019331 Mrpl9 mitochondrial ribosomal protein L9 K02939|1|4e-153|543|mmu:78523|large subunit ribosomal protein L9 GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression "gi|29789253|ref|NP_084392.1|/3.4555e-152/39S ribosomal protein L9, mitochondrial [Mus musculus]" 57312 1536 23.69666667 24.47 0.046329967 Up 0.165651209 Mrps31 mitochondrial ribosomal protein S31 K17410|1|0.0|659|mmu:57312|small subunit ribosomal protein S31 GO:0000314//organellar small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding - "gi|148700945|gb|EDL32892.1|/0/mitochondrial ribosomal protein S31, isoform CRA_b [Mus musculus]" 64659 1970 11.57 12.02333333 0.055448058 Up 0.165481966 Mrps14 mitochondrial ribosomal protein S14 K02954|1|2e-67|259|mmu:64659|small subunit ribosomal protein S14 GO:0000314//organellar small ribosomal subunit;GO:0005635//nuclear envelope - GO:0010467//gene expression "gi|13384894|ref|NP_079750.1|/1.70042e-66/28S ribosomal protein S14, mitochondrial [Mus musculus]" 66409 1839 22.86 23.62 0.047183561 Up 0.165425552 Rsl1d1 ribosomal L1 domain containing 1 K14775|1|0.0|696|mmu:66409|ribosome biogenesis protein UTP30 - - - gi|74216969|dbj|BAE26596.1|/0/unnamed protein product [Mus musculus] 64658 6076 10.82 11.26333333 0.057933351 Up 0.16478619 Mrps25 mitochondrial ribosomal protein S25 K17404|1|1e-85|322|mmu:64658|small subunit ribosomal protein S25 GO:0000314//organellar small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle - - "gi|31981257|ref|NP_079854.2|/1.00155e-84/28S ribosomal protein S25, mitochondrial [Mus musculus]" 66489 452 479.3266667 492.0066667 0.03766866 Up 0.163986987 Rpl35 ribosomal protein L35 K02918|1|3e-39|162|chx:102183339|large subunit ribosomal protein L35e GO:0031981//nuclear lumen;GO:0015934//large ribosomal subunit GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane "gi|119608008|gb|EAW87602.1|/1.13543e-38/ribosomal protein L35, isoform CRA_b [Homo sapiens]" 20103 768 343.8733333 353.4033333 0.039438405 Up 0.163620294 Rps5 ribosomal protein S5 K02989|1|7e-121|435|rro:104680873|small subunit ribosomal protein S5e GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity;GO:0003723//RNA binding GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0006613//cotranslational protein targeting to membrane;GO:0006448//regulation of translational elongation gi|431921423|gb|ELK18822.1|/2.38572e-120/40S ribosomal protein S5 [Pteropus alecto] 19942 734 154.6233333 158.9633333 0.039935986 Up 0.162266351 Rpl27 ribosomal protein L27 K02901|1|5e-65|249|cmy:102936559|large subunit ribosomal protein L27e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|528768520|gb|EPY88179.1|/9.97245e-65/60S ribosomal protein L27-like protein [Camelus ferus] 19981 601 169.6633333 165.55 -0.035407801 Down 0.162125315 Rpl37a ribosomal protein L37a K02921|1|4e-48|192|ocu:100353361|large subunit ribosomal protein L37Ae GO:0015934//large ribosomal subunit GO:0043169//cation binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|148692286|gb|EDL24233.1|/1.12854e-50/mCG7661 [Mus musculus] 19982 497 161.04 156.9866667 -0.036777045 Down 0.162087705 Rpl36a ribosomal protein L36A K02929|1|4e-65|248|ngi:103746226|large subunit ribosomal protein L44e - - - gi|640790559|ref|XP_008051148.1|/1.66887e-64/PREDICTED: 60S ribosomal protein L36a [Tarsius syrichta] 66047 587 89.26 91.76666667 0.039956398 Up 0.160583324 Mrpl54 mitochondrial ribosomal protein L54 K17435|1|2e-54|213|mmu:66047|large subunit ribosomal protein L54 GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle - - "gi|13384682|ref|NP_079593.1|/1.75031e-53/39S ribosomal protein L54, mitochondrial precursor [Mus musculus]" 60441 1411 67.26666667 69.26333333 0.042200051 Up 0.159708902 Mrpl38 mitochondrial ribosomal protein L38 K17419|1|0.0|781|mmu:60441|large subunit ribosomal protein L38 - - - "gi|124430535|ref|NP_077139.2|/0/39S ribosomal protein L38, mitochondrial precursor [Mus musculus]" 56280 1496 67.61666667 65.90333333 -0.037027459 Down 0.158825078 Mrpl37 mitochondrial ribosomal protein L37 K17418|1|0.0|763|mmu:56280|large subunit ribosomal protein L37 GO:0000313;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression "gi|22128625|ref|NP_079776.1|/0/39S ribosomal protein L37, mitochondrial precursor [Mus musculus]" 67707 949 53.46 54.85 0.037031783 Up 0.157386513 Mrpl24 mitochondrial ribosomal protein L24 K02895|1|6e-104|379|mmu:67707|large subunit ribosomal protein L24 GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression "gi|153792729|ref|NP_080867.2|/5.19356e-103/39S ribosomal protein L24, mitochondrial precursor [Mus musculus]" 66223 3695 13.67666667 14.13333333 0.047385111 Up 0.155900936 Mrpl35 mitochondrial ribosomal protein L35 K02916|1|2e-104|383|mmu:66223|large subunit ribosomal protein L35 GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0005198//structural molecule activity GO:0010467//gene expression "gi|13384830|ref|NP_079706.1|/1.6359e-103/39S ribosomal protein L35, mitochondrial [Mus musculus]" 66258 1196 28.55 29.44 0.044286926 Up 0.153296476 Mrps17 mitochondrial ribosomal protein S17 K02961|1|2e-53|212|mmu:66258|small subunit ribosomal protein S17 GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0003723//RNA binding;GO:0005198//structural molecule activity "GO:0006351//transcription, DNA-templated" "gi|13384854|ref|NP_079726.1|/1.58103e-52/28S ribosomal protein S17, mitochondrial precursor [Mus musculus]" 67308 1173 24.2 23.61 -0.035609006 Down 0.148341419 Mrpl46 mitochondrial ribosomal protein L46 K17427|1|4e-144|513|mmu:67308|large subunit ribosomal protein L46 GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity - "gi|12963643|ref|NP_075820.1|/3.21335e-143/39S ribosomal protein L46, mitochondrial [Mus musculus]" 67832 2654 5.353333333 5.593333333 0.063270823 Up 0.147645643 Brix1 "BRX1, biogenesis of ribosomes" K14820|1|0.0|722|mmu:67832|ribosome biogenesis protein BRX1 - - - - 67994 1043 20.33333333 20.88 0.03827497 Up 0.147354169 Mrps11 mitochondrial ribosomal protein S11 K02948|1|4e-90|333|mmu:67994|small subunit ribosomal protein S11 GO:0000314//organellar small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression "gi|170650663|ref|NP_080774.2|/2.90142e-89/28S ribosomal protein S11, mitochondrial [Mus musculus]" 665004 919 0.113333333 0.06 -0.91753784 Down 0.14546429 Gm7443 ribosomal protein L27 pseudogene - - - - - 319195 775 380.4866667 389.4766667 0.033691001 Up 0.144430027 Rpl17 ribosomal protein L17 K02880|1|5e-96|352|phd:102323682|large subunit ribosomal protein L17e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane "gi|28174920|gb|AAH03896.2|/4.45365e-98/Rpl17 protein, partial [Mus musculus]" 68172 805 0.073333333 0.126666667 0.788495895 Up 0.144016323 Rpl39l ribosomal protein L39-like K02924|1|4e-20|100|hgl:106008453|large subunit ribosomal protein L39e GO:0030529//intracellular ribonucleoprotein complex - GO:0010467//gene expression;GO:0048232//male gamete generation "gi|821142475|ref|XP_004482842.2|/1.17686e-19/PREDICTED: 60S ribosomal protein L39, partial [Dasypus novemcinctus]" 67097 573 331.67 325.9033333 -0.025304416 Down 0.143997518 Rps10 ribosomal protein S10 K02947|1|7e-74|260|umr:103665474|small subunit ribosomal protein S10e GO:0015935//small ribosomal subunit;GO:0031981//nuclear lumen GO:0005488//binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|671001540|ref|XP_008691634.1|/4.91867e-73/PREDICTED: 40S ribosomal protein S10 isoform X1 [Ursus maritimus] 20115 961 220.2766667 215.0733333 -0.034488024 Down 0.143884689 Rps7 ribosomal protein S7 K02993|1|5e-103|376|mdo:100028369|small subunit ribosomal protein S7e GO:0031981//nuclear lumen;GO:0030684//preribosome;GO:0015630//microtubule cytoskeleton;GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding GO:0006412//translation;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0006613//cotranslational protein targeting to membrane;GO:0042254//ribosome biogenesis "gi|148705008|gb|EDL36955.1|/2.12203e-112/mCG19129, partial [Mus musculus]" 67239 1498.17 5.333333333 5.543333333 0.055716264 Up 0.143470984 Rpf2 ribosome production factor 2 homolog K14847|1|8e-161|569|mmu:67239|ribosome production factor 2 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - - gi|110347519|ref|NP_075812.3|/2.07963e-164/ribosome production factor 2 homolog isoform 1 [Mus musculus] 100042948 3445 0.216666667 0.276666667 0.352671618 Up 0.143076084 Gm15760 mitochondrial ribosomal protein S18B pseudogene "K16174|1|3e-46|127|mmu:66973|small subunit ribosomal protein S18b, mitochondrial" GO:0043231//intracellular membrane-bounded organelle - - "gi|23956152|ref|NP_080154.1|/2.40086e-45/28S ribosomal protein S18b, mitochondrial [Mus musculus]" 66407 959 78.94 80.71 0.031990916 Up 0.141543495 Mrps15 mitochondrial ribosomal protein S15 K02956|1|1e-117|425|mmu:66407|small subunit ribosomal protein S15 GO:0000314//organellar small ribosomal subunit;GO:0005635//nuclear envelope GO:0005198//structural molecule activity GO:0010467//gene expression "gi|48526512|ref|NP_079820.2|/8.32528e-117/28S ribosomal protein S15, mitochondrial precursor [Mus musculus]" 68463 672 80.49333333 82.10333333 0.028571495 Up 0.141120388 Mrpl14 mitochondrial ribosomal protein L14 K02874|1|9e-78|291|mmu:68463|large subunit ribosomal protein L14 GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression "gi|21312028|ref|NP_081008.1|/7.17503e-77/39S ribosomal protein L14, mitochondrial precursor [Mus musculus]" 353258 1784 11.9 11.55666667 -0.042236238 Down 0.139183497 Ltv1 LTV1 ribosome biogenesis factor K14798|1|0.0|854|mmu:353258|protein LTV1 - - - - 68735 526 35.58 36.38666667 0.032343383 Up 0.137444056 Mrps18c mitochondrial ribosomal protein S18C K02963|1|2e-80|299|mmu:68735|small subunit ribosomal protein S18 GO:0000314//organellar small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression "gi|58037129|ref|NP_081102.1|/1.3194e-79/28S ribosomal protein S18c, mitochondrial [Mus musculus]" 75398 768 43.58666667 42.81333333 -0.025826712 Down 0.137020949 Mrpl32 mitochondrial ribosomal protein L32 K02911|1|1e-97|358|mmu:75398|large subunit ribosomal protein L32 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression "gi|21312948|ref|NP_083547.1|/8.25687e-97/39S ribosomal protein L32, mitochondrial [Mus musculus]" 118451 2053.02 32.44 33.15666667 0.031525156 Up 0.136447403 Mrps2 mitochondrial ribosomal protein S2 K02967|1|5e-165|583|mmu:118451|small subunit ribosomal protein S2 GO:0043231//intracellular membrane-bounded organelle;GO:0044391//ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0044391//ribosomal subunit - GO:0010467//gene expression;GO:0010467//gene expression "gi|148676435|gb|EDL08382.1|/7.19768e-153/mitochondrial ribosomal protein S2, isoform CRA_a [Mus musculus]" 72508 5395 5.086666667 4.896666667 -0.054920566 Down 0.135084057 Rps6kb1 "ribosomal protein S6 kinase, polypeptide 1" K04688|1|4e-104|382|mmu:72508|p70 ribosomal S6 kinase [EC:2.7.11.1] GO:0030529//intracellular ribonucleoprotein complex;GO:0031966//mitochondrial membrane;GO:0042995//cell projection;GO:0030529//intracellular ribonucleoprotein complex;GO:0031966//mitochondrial membrane;GO:0042995//cell projection GO:0004674//protein serine/threonine kinase activity;GO:0033218//amide binding;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0033218//amide binding;GO:0032550 GO:0014874;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0003006//developmental process involved in reproduction;GO:0006796//phosphate-containing compound metabolic process;GO:0031667//response to nutrient levels;GO:0007613//memory;GO:0031960//response to corticosteroid;GO:0006413//translational initiation;GO:0044772//mitotic cell cycle phase transition;GO:0048630//skeletal muscle tissue growth;GO:0043200//response to amino acid;GO:0070848//response to growth factor;GO:0006941//striated muscle contraction;GO:0002237//response to molecule of bacterial origin;GO:0010827//regulation of glucose transport;GO:0014891//striated muscle atrophy;GO:0006464//cellular protein modification process;GO:0009746;GO:0014909//smooth muscle cell migration;GO:0006950//response to stress;GO:0034097//response to cytokine;GO:0097305//response to alcohol;GO:0008286//insulin receptor signaling pathway;GO:0014874;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0048017//inositol lipid-mediated signaling;GO:0003006//developmental process involved in reproduction;GO:0006796//phosphate-containing compound metabolic process;GO:0031667//response to nutrient levels;GO:0007613//memory;GO:0031960//response to corticosteroid;GO:0006413//translational initiation;GO:0044772//mitotic cell cycle phase transition;GO:0048630//skeletal muscle tissue growth;GO:0043200//response to amino acid;GO:0070848//response to growth factor;GO:0006941//striated muscle contraction;GO:0002237//response to molecule of bacterial origin;GO:0010827//regulation of glucose transport;GO:0014891//striated muscle atrophy;GO:0006464//cellular protein modification process;GO:0009746;GO:0014909//smooth muscle cell migration;GO:0006950//response to stress;GO:0034097//response to cytokine;GO:0097305//response to alcohol;GO:0008286//insulin receptor signaling pathway gi|166999987|ref|NP_001107806.1|/0/ribosomal protein S6 kinase beta-1 isoform 1 [Mus musculus] 107733 2423 28.99 28.40666667 -0.029325783 Down 0.134519914 Mrpl41 mitochondrial ribosomal protein L41 K17422|1|1e-72|277|mmu:107733|large subunit ribosomal protein L41 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0012501//programmed cell death "gi|113461980|ref|NP_001026978.2|/1.01407e-71/39S ribosomal protein L41, mitochondrial precursor [Mus musculus]" 544707 907 0.063333333 0.106666667 0.752072487 Up 0.133589078 Gm5779 "ribosomal protein, large, P0 pseudogene" K02941|1|4e-79|231|cge:100756201|large subunit ribosomal protein LP0 GO:0005840//ribosome - GO:0070670//response to interleukin-4 gi|821563264|gb|AKH49591.1|/1.35231e-78/large ribosomal protein P0 [Peromyscus leucopus] 207932 7381 1.556666667 1.46 -0.09249168 Down 0.133335214 Urb1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) K14861|1|0.0|4184|mmu:207932|nucleolar pre-ribosomal-associated protein 1 GO:0031981//nuclear lumen - - gi|256818750|ref|NP_083773.1|/0/nucleolar pre-ribosomal-associated protein 1 [Mus musculus] 27176 864 463.4433333 470.2333333 0.020983864 Up 0.124384144 Rpl7a ribosomal protein L7A K02936|1|1e-125|451|xla:100037086|large subunit ribosomal protein L7Ae GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0022613//ribonucleoprotein complex biogenesis;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|148708155|gb|EDL40102.1|/6.54902e-127/mCG12602 [Mus musculus] 19951 504 407.8966667 403.1233333 -0.016982427 Down 0.124177291 Rpl32 ribosomal protein L32 K02912|1|3e-65|249|phd:102318579|large subunit ribosomal protein L32e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|655832893|ref|XP_008258430.1|/9.33048e-66/PREDICTED: 60S ribosomal protein L32 isoform X2 [Oryctolagus cuniculus] 67671 373.55 242.7066667 240.1333333 -0.015378056 Down 0.123575539 Rpl38 ribosomal protein L38 K02923|1|5e-20|98.2|hgl:101721072|large subunit ribosomal protein L38e GO:0070992;GO:0015934//large ribosomal subunit;GO:0070992;GO:0015934//large ribosomal subunit;GO:0070992;GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding GO:0006412//translation;GO:0000027//ribosomal large subunit assembly;GO:0007498//mesoderm development;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0050954//sensory perception of mechanical stimulus;GO:0042471//ear morphogenesis;GO:0006613//cotranslational protein targeting to membrane;GO:0006412//translation;GO:0000027//ribosomal large subunit assembly;GO:0007498//mesoderm development;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0050954//sensory perception of mechanical stimulus;GO:0042471//ear morphogenesis;GO:0006613//cotranslational protein targeting to membrane;GO:0006412//translation;GO:0000027//ribosomal large subunit assembly;GO:0007498//mesoderm development;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0050954//sensory perception of mechanical stimulus;GO:0042471//ear morphogenesis;GO:0006613//cotranslational protein targeting to membrane "gi|327358533|gb|AEA51113.1|/1.37113e-23/60S ribosomal protein L38, partial [Oryzias melastigma]" 114641 1054.01 119.7466667 121.49 0.020852072 Up 0.122964384 Rpl31 ribosomal protein L31 K02910|1|1e-60|235|mmu:665562|large subunit ribosomal protein L31e GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit;GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|148672373|gb|EDL04320.1|/1.08338e-67/mCG49427 [Mus musculus] 66483 525 94.76666667 93.49333333 -0.019516198 Down 0.122372034 Rpl36al ribosomal protein L36A-like K02929|1|1e-60|234|lve:103086143|large subunit ribosomal protein L44e - - - "gi|148704679|gb|EDL36626.1|/8.84747e-68/mCG7611, isoform CRA_c, partial [Mus musculus]" 67681 959 89.84333333 90.98333333 0.018190836 Up 0.12204295 Mrpl18 mitochondrial ribosomal protein L18 K02881|1|2e-101|371|mmu:67681|large subunit ribosomal protein L18 GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0019843//rRNA binding GO:0035927//RNA import into mitochondrion;GO:0010467//gene expression "gi|13385808|ref|NP_080586.1|/1.42668e-100/39S ribosomal protein L18, mitochondrial [Mus musculus]" 267019 5158 8.553333333 8.73 0.029494889 Up 0.119983828 Rps15a ribosomal protein S15A K02957|1|2e-69|268|ssc:100626041|small subunit ribosomal protein S15Ae - - - "gi|30109302|gb|AAH51205.1|/1.70081e-69/Rps15a protein, partial [Mus musculus]" 67036 2431 33.74 34.29 0.023327931 Up 0.119212832 Mrpl45 mitochondrial ribosomal protein L45 K17426|1|7e-161|570|mmu:67036|large subunit ribosomal protein L45 GO:0005743//mitochondrial inner membrane;GO:0030529//intracellular ribonucleoprotein complex GO:0008320//protein transmembrane transporter activity GO:0015031//protein transport "gi|13385418|ref|NP_080203.1|/5.81295e-160/39S ribosomal protein L45, mitochondrial [Mus musculus]" 73086 4406 1.413333333 1.343333333 -0.073284426 Down 0.118423032 Rps6ka5 "ribosomal protein S6 kinase, polypeptide 5" K04445|1|0.0|1601|mmu:73086|ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1] GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0032550 GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0019221//cytokine-mediated signaling pathway;GO:0035404//histone-serine phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0006935//chemotaxis;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0038127//ERBB signaling pathway;GO:0000165//MAPK cascade;GO:0001816//cytokine production "gi|148686947|gb|EDL18894.1|/0/ribosomal protein S6 kinase, polypeptide 5, isoform CRA_a, partial [Mus musculus]" 56284 5016 7.456666667 7.593333333 0.026202491 Up 0.116382715 Mrpl19 mitochondrial ribosomal protein L19 K02884|1|9e-158|561|mmu:56284|large subunit ribosomal protein L19 GO:0000313;GO:0005635//nuclear envelope - GO:0010467//gene expression "gi|13385976|ref|NP_080766.1|/7.98065e-157/39S ribosomal protein L19, mitochondrial [Mus musculus]" 28028 2103 22.99333333 22.65666667 -0.021280006 Down 0.115780962 Mrpl50 mitochondrial ribosomal protein L50 K17431|1|5e-62|241|mmu:28028|large subunit ribosomal protein L50 GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle - - "gi|30519921|ref|NP_848718.1|/3.99477e-61/39S ribosomal protein L50, mitochondrial [Mus musculus]" 621697 592 0.226666667 0.26 0.197939378 Up 0.112546542 Rpl32l ribosomal protein L32-like K02912|1|6e-59|228|phd:102318579|large subunit ribosomal protein L32e - - - - 67945 459 894.26 888.5033333 -0.009317157 Down 0.104893001 Rpl41 ribosomal protein L41 - - - - "gi|148692636|gb|EDL24583.1|/1.06229e-20/mCG130546, isoform CRA_b, partial [Mus musculus]" 27207 602 354.3633333 351.13 -0.01322407 Down 0.104695551 Rps11 ribosomal protein S11 K02949|1|5e-87|322|pale:102880386|small subunit ribosomal protein S11e GO:0015935//small ribosomal subunit GO:0003723//RNA binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|744603787|ref|XP_010991488.1|/3.24569e-90/PREDICTED: 40S ribosomal protein S11 [Camelus dromedarius] 19896 830 208.63 209.7333333 0.007609545 Up 0.103971567 Rpl10a ribosomal protein L10A K02865|1|2e-104|380|pale:102897987|large subunit ribosomal protein L10Ae GO:0043231//intracellular membrane-bounded organelle;GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane;GO:0032502//developmental process gi|531171|gb|AAA86463.1|/1.81658e-103/Csa-19 [Homo sapiens] 27398 1037.27 73.55 74.2 0.012693845 Up 0.10315356 Mrpl2 mitochondrial ribosomal protein L2 K02886|1|3e-138|493|mmu:27398|large subunit ribosomal protein L2 - - - - 19935 582 100.4766667 101.0633333 0.008399161 Up 0.102965512 Mrpl23 mitochondrial ribosomal protein L23 K02892|1|8e-68|258|mmu:19935|large subunit ribosomal protein L23 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0005198//structural molecule activity GO:0010467//gene expression "gi|6755352|ref|NP_035418.1|/5.99334e-67/39S ribosomal protein L23, mitochondrial [Mus musculus]" 68537 786 72.49666667 72.91333333 0.008267995 Up 0.102109895 Mrpl13 mitochondrial ribosomal protein L13 K02871|1|3e-102|373|mmu:68537|large subunit ribosomal protein L13 GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression "gi|21312936|ref|NP_081035.1|/1.99734e-101/39S ribosomal protein L13, mitochondrial [Mus musculus]" 79044 899 56.37666667 56.75 0.009522213 Up 0.101686788 Mrps34 mitochondrial ribosomal protein S34 K17412|1|1e-100|368|mmu:79044|small subunit ribosomal protein S34 GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle - - "gi|148690434|gb|EDL22381.1|/9.13002e-107/mitochondrial ribosomal protein S34, isoform CRA_a, partial [Mus musculus]" 52443 966.3 50.24 50.50333333 0.007542148 Up 0.100643123 Mrpl48 mitochondrial ribosomal protein L48 K17429|1|2e-103|377|mmu:52443|large subunit ribosomal protein L48 GO:0000313;GO:0043231//intracellular membrane-bounded organelle;GO:0000313;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0010467//gene expression;GO:0010467//gene expression "gi|148368964|ref|NP_942128.2|/1.2784e-98/39S ribosomal protein L48, mitochondrial precursor [Mus musculus]" 67871 2251 22.13666667 21.91 -0.014848514 Down 0.100238821 Mrrf mitochondrial ribosome recycling factor K02838|1|4e-136|488|mmu:67871|ribosome recycling factor GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression;GO:0032988 "gi|148670216|gb|EDL02163.1|/2.16292e-153/mCG10533, isoform CRA_c [Mus musculus]" 64655 1230 16.54333333 16.68333333 0.012157614 Up 0.098057467 Mrps22 mitochondrial ribosomal protein S22 K17401|1|2e-180|634|mmu:64655|small subunit ribosomal protein S22 GO:0000314//organellar small ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle - - "gi|13384904|ref|NP_079761.1|/1.7573e-179/28S ribosomal protein S22, mitochondrial [Mus musculus]" 67071 4683 0.016666667 0.01 -0.736965594 Down 0.097916432 Rps6ka6 ribosomal protein S6 kinase polypeptide 6 K04373|1|0.0|1711|mmu:67071|p90 ribosomal S6 kinase [EC:2.7.11.1] - - - - 381827 4600 0.01 0.016666667 0.736965594 Up 0.097916432 1700073E17Rik ribosomal protein L7 pseudogene K02937|1|4e-70|270|cjc:100408843|large subunit ribosomal protein L7e GO:0015934//large ribosomal subunit GO:0003723//RNA binding;GO:0042802//identical protein binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0042254//ribosome biogenesis;GO:0006613//cotranslational protein targeting to membrane gi|823413647|ref|XP_004403961.2|/2.56632e-69/PREDICTED: LOW QUALITY PROTEIN: 60S ribosomal protein L7 [Odobenus rosmarus divergens] 64934 2911 16.05 16.17 0.010746381 Up 0.097164241 Pes1 pescadillo ribosomal biogenesis factor 1 K14843|1|0.0|1055|mmu:64934|pescadillo GO:0031981//nuclear lumen;GO:0030686//90S preribosome;GO:0005694//chromosome GO:0005488//binding GO:0000470//maturation of LSU-rRNA;GO:0007049//cell cycle;GO:0034613//cellular protein localization;GO:0006997//nucleus organization;GO:0000460//maturation of 5.8S rRNA gi|12584984|ref|NP_075027.1|/0/pescadillo homolog [Mus musculus] 58988 1491 15.96333333 15.87333333 -0.008156815 Down 0.095490616 Rps6kb2 "ribosomal protein S6 kinase, polypeptide 2" K04688|1|0.0|796|mmu:58988|p70 ribosomal S6 kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0033218//amide binding GO:0006413//translational initiation;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process gi|10946894|ref|NP_067460.1|/0/ribosomal protein S6 kinase beta-2 [Mus musculus] 665268 1809 0.173333333 0.186666667 0.106915204 Up 0.091005679 1600029O15Rik ribosomal protein L17 pseudogene K02880|1|1e-64|250|phd:102323682|large subunit ribosomal protein L17e - - - gi|74199731|dbj|BAB24124.2|/1.74281e-110/unnamed protein product [Mus musculus] 68193 686 367.6566667 366.3966667 -0.004952767 Down 0.086943849 Rpl24 ribosomal protein L24 K02896|1|2e-56|220|shr:100915234|large subunit ribosomal protein L24e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding GO:0007411//axon guidance;GO:0000075//cell cycle checkpoint;GO:0043010//camera-type eye development;GO:0006412//translation;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0019080;GO:0021545//cranial nerve development;GO:0000087//mitotic M phase;GO:0006613//cotranslational protein targeting to membrane "gi|28174943|gb|AAH02110.2|/1.08587e-59/Rpl24 protein, partial [Mus musculus]" 68052 585 263.7633333 264.4466667 0.003732766 Up 0.086821618 Rps13 ribosomal protein S13 K02953|1|1e-80|300|pbi:103049505|small subunit ribosomal protein S13e - - - - 633395 2629 0.343333333 0.336666667 -0.028289044 Down 0.086295084 Gm10548 ribosomal protein L29 pseudogene K02905|1|2e-38|163|rno:29283|large subunit ribosomal protein L29e GO:0015934//large ribosomal subunit;GO:0044425 GO:0005539//glycosaminoglycan binding GO:0007155//cell adhesion;GO:0010467//gene expression;GO:0040007//growth gi|74205455|dbj|BAE21038.1|/1.16787e-44/unnamed protein product [Mus musculus] 69163 1424 40.86 40.95333333 0.003291679 Up 0.085777953 Mrpl44 mitochondrial ribosomal protein L44 K17425|1|1e-154|548|mmu:69163|large subunit ribosomal protein L44 [EC:3.1.26.-] GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex "GO:0003723//RNA binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters" GO:0010467//gene expression "gi|124487075|ref|NP_001074679.1|/9.15251e-154/39S ribosomal protein L44, mitochondrial precursor [Mus musculus]" 100042584 4750 0.016666667 0.02 0.263034406 Up 0.080089511 Gm16523 mitochondrial ribosomal protein L40 pseudogene K17421|1|3e-21|76.6|ngi:103742069|large subunit ribosomal protein L40 - - - "gi|829825385|ref|XP_012632056.1|/1.29487e-20/PREDICTED: 39S ribosomal protein L40, mitochondrial [Microcebus murinus]" 100039636 1133 0.383333333 16.52666667 5.430052505 Up 0.955291662 Atp6v0c-ps2 "ATPase, H+ transporting, lysosomal V0 subunit C, pseudogene 2" K02155|1|6e-66|247|cge:100772184|V-type H+-transporting ATPase 16kDa proteolipid subunit GO:0005774//vacuolar membrane;GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0033176//proton-transporting V-type ATPase complex "GO:0044389//ubiquitin-like protein ligase binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0015077//monovalent inorganic cation transmembrane transporter activity" "GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0051452//intracellular pH reduction;GO:0035751//regulation of lysosomal lumen pH" gi|148699288|gb|EDL31235.1|/2.34395e-85/mCG22073 [Mus musculus] 102465702 54 0.01 9.46 9.885696373 Up 0.943237805 Mir7219 microRNA 7219 - - - - - 102465886 117 0.01 9.083333333 9.827078014 Up 0.940764978 Mir8094 microRNA 8094 K12812|1|9e-13|73.9|cge:103160562|ATP-dependent RNA helicase UAP56/SUB2 [EC:3.6.4.13] - - - - 102466229 54 0.01 8.706666667 9.765976681 Up 0.938395577 Mir7225 microRNA 7225 - - - - - 16145 2064 12.84 80.97666667 2.656861055 Up 0.924019331 Igtp interferon gamma induced GTPase K14140|1|0.0|839|mmu:16145|interferon gamma induced GTPase;K14139|3|5e-98|361|ngi:103744225|immunity-related GTPase family M protein [EC:3.6.5.-] - - - - 102466785 69 5.91 0.01 -9.20701432 Down 0.910733762 Mir7005 microRNA 7005 - - - - gi|568920137|ref|XP_006500638.1|/9.0454e-06/PREDICTED: laminin subunit alpha-5 isoform X1 [Mus musculus] 100217431 59 4.38 0.01 -8.77478706 Down 0.882517206 Snord69 "small nucleolar RNA, C/D box 69" - - - - - 319171 452 0.696666667 7.61 3.449356012 Up 0.877214262 Hist1h2ap "histone cluster 1, H2ap" K11251|1|1e-54|213|ocu:100348744|histone H2A;K11254|4|1e-54|213|cfa:488260|histone H4 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|655839886|ref|XP_002714260.2|/9.56752e-54/PREDICTED: histone H2A type 1-like [Oryctolagus cuniculus] 545637 1325 4.1 0.01 -8.6794801 Down 0.875333785 Gm11758 predicted gene 11758 - - - - gi|294831974|ref|NP_001171049.1|/0/uncharacterized protein LOC667780 [Mus musculus] 103988 2372 28.07666667 7.423333333 -1.919232608 Down 0.875239761 Gck glucokinase K12407|1|0.0|869|ggo:101138839|glucokinase [EC:2.7.1.2] - - - gi|31982798|ref|NP_034422.2|/0/glucokinase isoform 1 [Mus musculus] 626578 3528 6.323333333 24.22 1.937441687 Up 0.872325022 Gbp10 guanylate-binding protein 10 K17339|1|4e-17|93.6|hro:HELRODRAFT_73066|atlastin [EC:3.6.5.-] GO:0031982//vesicle;GO:0020003//symbiont-containing vacuole - GO:0001562//response to protozoan;GO:0042742//defense response to bacterium;GO:0034341//response to interferon-gamma;GO:0032496//response to lipopolysaccharide;GO:0035456//response to interferon-beta;GO:0051702//interaction with symbiont gi|116812914|ref|NP_001034735.2|/0/guanylate-binding protein 10 [Mus musculus] 225594 2838 2.983333333 14.68333333 2.299182432 Up 0.870322314 Gm4841 predicted gene 4841 K17072|1|2e-81|306|mmu:432555|interferon gamma inducible protein 47 - - - gi|294712534|ref|NP_001030031.2|/0/interferon-inducible GTPase-like [Mus musculus] 100302529 60 0.01 3.763333333 8.55586727 Up 0.865630524 Snord72 "small nucleolar RNA, C/D box 72" - - - - - 60440 2971.11 7.796666667 24.79333333 1.669022886 Up 0.862198654 Iigp1 interferon inducible GTPase 1 K17072|1|3e-101|372|mmu:432555|interferon gamma inducible protein 47 GO:0043231//intracellular membrane-bounded organelle;GO:0020003//symbiont-containing vacuole;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0020003//symbiont-containing vacuole;GO:0031090//organelle membrane GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity GO:0007166//cell surface receptor signaling pathway;GO:0001562//response to protozoan;GO:0042742//defense response to bacterium;GO:0006914//autophagy;GO:0009154//purine ribonucleotide catabolic process;GO:0035456//response to interferon-beta;GO:0007166//cell surface receptor signaling pathway;GO:0001562//response to protozoan;GO:0042742//defense response to bacterium;GO:0006914//autophagy;GO:0009154//purine ribonucleotide catabolic process;GO:0035456//response to interferon-beta "gi|545719891|pdb|4LV5|B/0/Chain B, Murine Irga6 Bound To Toxoplasma Rop5b, A Pseudokinase Gdi" 399548 4244 14.05333333 40.33333333 1.521060275 Up 0.861841363 Scn4b "sodium channel, type IV, beta" K04848|1|7e-92|342|mmu:399548|voltage-gated sodium channel type IV beta - - - - 230899 860 302.53 129.38 -1.225463595 Down 0.861314829 Nppa natriuretic peptide type A K12334|1|2e-72|274|mmu:230899|natriuretic peptide A - - - - 319192 596 1.186666667 8.04 2.760280761 Up 0.856698259 Hist2h2aa2 "histone cluster 2, H2aa2" K11251|1|7e-55|215|ssc:100511884|histone H2A GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|817939|emb|CAA83210.1|/6.74336e-56/histone H2A [Mus musculus domesticus] 54396 3537 10.62666667 29.71 1.483259477 Up 0.851799616 Irgm2 immunity-related GTPase family M member 2 K14140|1|2e-90|337|mmu:16145|interferon gamma induced GTPase;K14139|3|3e-82|310|ngi:103744225|immunity-related GTPase family M protein [EC:3.6.5.-] GO:0043231//intracellular membrane-bounded organelle;GO:0033655 - GO:0006952//defense response;GO:0009154//purine ribonucleotide catabolic process;GO:0001562//response to protozoan;GO:0034097//response to cytokine gi|205360909|ref|NP_062313.3|/0/interferon inducible GTPase 2 [Mus musculus] 72961 3011 16.49666667 4.906666667 -1.749359371 Down 0.851658581 Slc17a7 "solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7" "K12302|1|0.0|1050|rno:116638|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8" GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle;GO:0042995//cell projection GO:0005436//sodium:phosphate symporter activity GO:0007613//memory;GO:0051899//membrane depolarization;GO:0015813//L-glutamate transport;GO:0001505//regulation of neurotransmitter levels;GO:0007270//neuron-neuron synaptic transmission;GO:0006817//phosphate ion transport gi|218156282|ref|NP_892038.2|/0/vesicular glutamate transporter 1 [Mus musculus] 100628576 59 0.01 3.32 8.375039431 Up 0.850727745 Mir5046 microRNA 5046 - - - - - 102465556 66 3.316666667 0.01 -8.373590215 Down 0.85070894 Mir6922 microRNA 6922 - - - - - 107765 1765 521.0133333 252.8566667 -1.043000477 Down 0.842425439 Ankrd1 ankyrin repeat domain 1 (cardiac muscle) K11420|1|5e-22|108|ola:101167635|euchromatic histone-lysine N-methyltransferase [EC:2.1.1.43];K15504|2|2e-21|106|bacu:103014484|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C GO:0030017//sarcomere;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0008134//transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0008092//cytoskeletal protein binding;GO:0003676//nucleic acid binding;GO:0019899//enzyme binding;GO:0046332//SMAD binding "GO:0070555//response to interleukin-1;GO:0006915//apoptotic process;GO:0009612//response to mechanical stimulus;GO:0014070//response to organic cyclic compound;GO:0051053//negative regulation of DNA metabolic process;GO:0001666//response to hypoxia;GO:0010975//regulation of neuron projection development;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0003007//heart morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0071363//cellular response to growth factor stimulus;GO:0042493//response to drug;GO:0007519//skeletal muscle tissue development;GO:0009306//protein secretion;GO:0034612//response to tumor necrosis factor;GO:0032496//response to lipopolysaccharide" gi|31560506|ref|NP_038496.2|/1.49272e-151/ankyrin repeat domain-containing protein 1 [Mus musculus] 623272 1292 0.056666667 3.27 5.850646485 Up 0.840996277 Gm11757 predicted gene 11757 - - - - gi|147899982|ref|NP_001079007.1|/0/uncharacterized protein LOC623272 [Mus musculus] 57262 598 12.68 3.88 -1.708426188 Down 0.836003611 Retnla resistin like alpha K13438|1|3e-15|83.6|cge:100769021|resistin - GO:0005102//receptor binding - gi|103472022|ref|NP_065255.2|/4.57261e-68/resistin-like alpha [Mus musculus] 15289 2890.78 48.81 22.19666667 -1.136833712 Down 0.834894129 Hmgb1 high mobility group box 1 K10802|1|1e-86|323|pale:102882684|high mobility group protein B1 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0005694//chromosome;GO:0044421;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0005694//chromosome;GO:0044421 GO:0008289//lipid binding;GO:0005102//receptor binding;GO:0008134//transcription factor binding;GO:0019843//rRNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005539//glycosaminoglycan binding;GO:0033218//amide binding;GO:0000400//four-way junction DNA binding;GO:0019887//protein kinase regulator activity;GO:0008289//lipid binding;GO:0005102//receptor binding;GO:0008134//transcription factor binding;GO:0019843//rRNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005539//glycosaminoglycan binding;GO:0033218//amide binding;GO:0000400//four-way junction DNA binding;GO:0019887//protein kinase regulator activity GO:0006954//inflammatory response;GO:0006284//base-excision repair;GO:0001932//regulation of protein phosphorylation;GO:0070555//response to interleukin-1;GO:0045445//myoblast differentiation;GO:0008284//positive regulation of cell proliferation;GO:0043434//response to peptide hormone;GO:0032989;GO:0007423//sensory organ development;GO:0002562;GO:0006266//DNA ligation;GO:0031960//response to corticosteroid;GO:0042742//defense response to bacterium;GO:0030595//leukocyte chemotaxis;GO:0002274;GO:0030099//myeloid cell differentiation;GO:0010975//regulation of neuron projection development;GO:0000278//mitotic cell cycle;GO:0071103//DNA conformation change;GO:0002237//response to molecule of bacterial origin;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006260//DNA replication;GO:0048511//rhythmic process;GO:0005980//glycogen catabolic process;GO:0051099//positive regulation of binding;GO:0009746;GO:0030036//actin cytoskeleton organization;GO:0030323//respiratory tube development;GO:0014909//smooth muscle cell migration;GO:0016568//chromatin modification;GO:0033028//myeloid cell apoptotic process;GO:0050927//positive regulation of positive chemotaxis;GO:0006954//inflammatory response;GO:0006284//base-excision repair;GO:0001932//regulation of protein phosphorylation;GO:0070555//response to interleukin-1;GO:0045445//myoblast differentiation;GO:0008284//positive regulation of cell proliferation;GO:0043434//response to peptide hormone;GO:0032989;GO:0007423//sensory organ development;GO:0002562;GO:0006266//DNA ligation;GO:0031960//response to corticosteroid;GO:0042742//defense response to bacterium;GO:0030595//leukocyte chemotaxis;GO:0002274;GO:0030099//myeloid cell differentiation;GO:0010975//regulation of neuron projection development;GO:0000278//mitotic cell cycle;GO:0071103//DNA conformation change;GO:0002237//response to molecule of bacterial origin;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006260//DNA replication;GO:0048511//rhythmic process;GO:0005980//glycogen catabolic process;GO:0051099//positive regulation of binding;GO:0009746;GO:0030036//actin cytoskeleton organization;GO:0030323//respiratory tube development;GO:0014909//smooth muscle cell migration;GO:0016568//chromatin modification;GO:0033028//myeloid cell apoptotic process;GO:0050927//positive regulation of positive chemotaxis "gi|148673911|gb|EDL05858.1|/1.1875e-88/mCG144566, partial [Mus musculus]" 15368 1634 17.75666667 39.58 1.156410832 Up 0.832186242 Hmox1 heme oxygenase 1 K00510|1|5e-164|580|mmu:15368|heme oxygenase (biliverdin-producing) [EC:1.14.14.18] - - - - 100217454 53 0.01 2.833333333 8.14635653 Up 0.829515965 Snord37 "small nucleolar RNA, C/D box 37" - - - - - 100216540 68 0.01 2.81 8.13442632 Up 0.828575727 Snord95 "small nucleolar RNA, C/D box 95" - - - - - 15077 664 2.756666667 0.01 -8.106781018 Down 0.826018278 Hist2h3c1 "histone cluster 2, H3c1" K11254|1|2e-71|270|pps:100972611|histone H4;K11253|4|3e-71|270|dre:100006146|histone H3 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding - gi|27372732|gb|AAO06264.1|/3.95297e-96/histone protein Hist2h3c1 [Mus musculus] 15944 2227 13.96 31.08333333 1.154842283 Up 0.825397721 Irgm1 immunity-related GTPase family M member 1 K14139|1|0.0|766|mmu:15944|immunity-related GTPase family M protein [EC:3.6.5.-] GO:0000323//lytic vacuole;GO:0044459;GO:0005768//endosome;GO:0005774//vacuolar membrane;GO:0030666//endocytic vesicle membrane GO:0032550;GO:0016787//hydrolase activity GO:0006952//defense response;GO:0044248;GO:0035456//response to interferon-beta gi|6680351|ref|NP_032352.1|/0/immunity-related GTPase family M protein 1 [Mus musculus] 14969 1669 21.44333333 44.63 1.057484619 Up 0.823498439 H2-Eb1 "histocompatibility 2, class II antigen E beta" "K06752|1|8e-141|503|mmu:14969|major histocompatibility complex, class II" GO:0005764//lysosome;GO:0005770//late endosome;GO:0009986//cell surface;GO:0042611;GO:0031224//intrinsic component of membrane GO:0003823//antigen binding GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;GO:0032653;GO:0001818//negative regulation of cytokine production;GO:0006959//humoral immune response;GO:0002437//inflammatory response to antigenic stimulus;GO:0034097//response to cytokine;GO:0051259//protein oligomerization;GO:0002478;GO:0009581;GO:0032024//positive regulation of insulin secretion;GO:0042098//T cell proliferation "gi|114431228|ref|NP_034512.2|/7.16226e-140/H-2 class II histocompatibility antigen, I-E beta chain precursor [Mus musculus]" 14961 1193 32.15 64.33666667 1.000822453 Up 0.82342322 H2-Ab1 "histocompatibility 2, class II antigen A, beta 1" "K06752|1|1e-131|472|mmu:14961|major histocompatibility complex, class II" GO:0031224//intrinsic component of membrane;GO:0042611;GO:0009986//cell surface;GO:0005770//late endosome GO:0044389//ubiquitin-like protein ligase binding;GO:0046983//protein dimerization activity;GO:0008134//transcription factor binding;GO:0003823//antigen binding GO:0046631//alpha-beta T cell activation;GO:0002478;GO:0006959//humoral immune response;GO:0034341//response to interferon-gamma;GO:0042098//T cell proliferation;GO:0002577//regulation of antigen processing and presentation;GO:0002824;GO:0002377//immunoglobulin production "gi|294997230|ref|NP_996988.2|/8.44312e-131/histocompatibility 2, class II antigen A, beta 1 precursor [Mus musculus]" 17153 2688.69 9.296666667 2.586666667 -1.845619377 Down 0.823206965 Mal "myelin and lymphocyte protein, T cell differentiation protein" - GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0044459 GO:0005488//binding;GO:0022803//passive transmembrane transporter activity;GO:0005198//structural molecule activity;GO:0016504//peptidase activator activity;GO:0005488//binding;GO:0022803//passive transmembrane transporter activity;GO:0005198//structural molecule activity;GO:0016504//peptidase activator activity GO:0031580//membrane raft distribution;GO:0012502//induction of programmed cell death;GO:0008366//axon ensheathment;GO:0048869//cellular developmental process;GO:0008105//asymmetric protein localization;GO:0015031//protein transport;GO:0031580//membrane raft distribution;GO:0012502//induction of programmed cell death;GO:0008366//axon ensheathment;GO:0048869//cellular developmental process;GO:0008105//asymmetric protein localization gi|6857808|ref|NP_034892.1|/1.36906e-75/myelin and lymphocyte protein isoform 1 [Mus musculus] 234593 2964.74 152.5466667 78.23 -0.963456786 Down 0.820865772 Ndrg4 N-myc downstream regulated gene 4 K18266|1|4e-108|395|mdo:100032580|protein NDRG1 GO:0044424;GO:0044444//cytoplasmic part - GO:0050896//response to stimulus;GO:0040007//growth;GO:0048869//cellular developmental process;GO:0050896//response to stimulus;GO:0040007//growth;GO:0048869//cellular developmental process gi|21704212|ref|NP_663577.1|/9.10848e-179/protein NDRG4 isoform B [Mus musculus] 100217457 55 0.01 2.59 8.016808288 Up 0.817189439 Snord58b "small nucleolar RNA, C/D box 58B" - - - - - 18145 5209 41.08 20.21666667 -1.022891037 Down 0.816493663 Npc1 Niemann-Pick type C1 K12385|1|0.0|2504|mmu:18145|Niemann-Pick C1 protein GO:0016021//integral component of membrane;GO:0000323//lytic vacuole;GO:0012505//endomembrane system GO:0032934//sterol binding;GO:0004888//transmembrane signaling receptor activity GO:0010507//negative regulation of autophagy;GO:0016125//sterol metabolic process;GO:0007034//vacuolar transport;GO:0055098//response to low-density lipoprotein particle;GO:0016192//vesicle-mediated transport;GO:0010038//response to metal ion;GO:0030301//cholesterol transport;GO:0006464//cellular protein modification process;GO:0032870//cellular response to hormone stimulus;GO:0055092//sterol homeostasis;GO:0008344//adult locomotory behavior gi|89242146|ref|NP_032746.2|/0/Niemann-Pick C1 protein precursor [Mus musculus] 329251 3118.83 19.19 8.29 -1.210910705 Down 0.814622588 Ppp1r12b "protein phosphatase 1, regulatory (inhibitor) subunit 12B" - GO:0044424 - - gi|148677466|gb|EDL09413.1|/1.35626e-15/mCG147326 [Mus musculus] 57266 1848 21.98333333 9.93 -1.146544536 Down 0.813578924 Cxcl14 chemokine (C-X-C motif) ligand 14 K10033|1|4e-52|181|ecb:100072697|C-X-C motif chemokine 14 GO:0044421;GO:0043231//intracellular membrane-bounded organelle GO:0005125//cytokine activity GO:0002376//immune system process;GO:0043583//ear development gi|545185816|ref|XP_005599768.1|/3.61733e-51/PREDICTED: C-X-C motif chemokine 14 [Equus caballus] 102465604 61 1.963333333 7.373333333 1.909011846 Up 0.807100681 Mir6999 microRNA 6999 - - - - - 18158 781 127.51 69.69 -0.871586835 Down 0.804684268 Nppb natriuretic peptide type B K12335|1|7e-49|196|mmu:18158|natriuretic peptide B GO:0043231//intracellular membrane-bounded organelle;GO:0044421;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044421;GO:0044444//cytoplasmic part GO:0051427//hormone receptor binding;GO:0051427//hormone receptor binding GO:0003018;GO:0009612//response to mechanical stimulus;GO:0009152//purine ribonucleotide biosynthetic process;GO:0008015//blood circulation;GO:0008285//negative regulation of cell proliferation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0010038//response to metal ion;GO:0044767//single-organism developmental process;GO:0016049//cell growth;GO:0002237//response to molecule of bacterial origin;GO:0009725//response to hormone;GO:0006952//defense response;GO:0003018;GO:0009612//response to mechanical stimulus;GO:0009152//purine ribonucleotide biosynthetic process;GO:0008015//blood circulation;GO:0008285//negative regulation of cell proliferation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0010038//response to metal ion;GO:0044767//single-organism developmental process;GO:0016049//cell growth;GO:0002237//response to molecule of bacterial origin;GO:0009725//response to hormone;GO:0006952//defense response gi|568930749|ref|XP_006538690.1|/5.61408e-48/PREDICTED: natriuretic peptides B isoform X1 [Mus musculus] 102465775 58 2.356666667 0.01 -7.880603904 Down 0.804185942 Mir7675 microRNA 7675 - - - - - 100628612 82 4.286666667 11.28 1.395838926 Up 0.802672158 Mir5113 microRNA 5113 - - - - - 76886 2883 6.563333333 1.66 -1.983245464 Down 0.800124111 Fam81a "family with sequence similarity 81, member A" K10352|1|2e-10|70.9|rro:104680597|myosin heavy chain;K06674|5|1e-08|65.1|tca:662857|structural maintenance of chromosome 2 - - - gi|58037475|ref|NP_084060.1|/0/protein FAM81A [Mus musculus] 101488143 646 18.54666667 35.75666667 0.947052332 Up 0.796692241 Hbb-bt "hemoglobin, beta adult t chain" K13823|1|7e-80|298|mmu:100503605|hemoglobin subunit beta GO:0043234//protein complex GO:0046906//tetrapyrrole binding;GO:0022892//substrate-specific transporter activity;GO:0046914//transition metal ion binding GO:0001932//regulation of protein phosphorylation;GO:0015669;GO:0030218//erythrocyte differentiation "gi|31982300|ref|NP_032246.2|/5.32982e-79/hemoglobin, beta adult t chain [Mus musculus]" 102466840 58 0.01 2.23 7.8008999 Up 0.795563955 Mir7655 microRNA 7655 - - - - - 100526556 76 0.01 2.21 7.787902559 Up 0.794285231 Mir3091 microRNA 3091 - - - - - 16149 1282.14 131.42 226.9266667 0.788041306 Up 0.79333559 Cd74 "CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)" K06505|1|3e-88|327|mmu:16149|CD74 antigen GO:0009986//cell surface;GO:0000323//lytic vacuole;GO:0043235//receptor complex;GO:0016021//integral component of membrane;GO:0042611;GO:0005770//late endosome;GO:0009986//cell surface;GO:0000323//lytic vacuole;GO:0043235//receptor complex;GO:0016021//integral component of membrane;GO:0042611;GO:0005770//late endosome GO:0042287//MHC protein binding;GO:0042277//peptide binding;GO:0004888//transmembrane signaling receptor activity;GO:0019955//cytokine binding;GO:0019899//enzyme binding;GO:0042287//MHC protein binding;GO:0042277//peptide binding;GO:0004888//transmembrane signaling receptor activity;GO:0019955//cytokine binding;GO:0019899//enzyme binding "GO:0002901;GO:0008284//positive regulation of cell proliferation;GO:0002790//peptide secretion;GO:0043383//negative T cell selection;GO:0031349//positive regulation of defense response;GO:0019724//B cell mediated immunity;GO:0015031//protein transport;GO:0043410//positive regulation of MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0032722//positive regulation of chemokine production;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0030888//regulation of B cell proliferation;GO:0006693//prostaglandin metabolic process;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0051084//'de novo' posttranslational protein folding;GO:0043368//positive T cell selection;GO:0002468//dendritic cell antigen processing and presentation;GO:0010934//macrophage cytokine production;GO:0065003;GO:0002828//regulation of type 2 immune response;GO:0002478;GO:0002901;GO:0008284//positive regulation of cell proliferation;GO:0002790//peptide secretion;GO:0043383//negative T cell selection;GO:0031349//positive regulation of defense response;GO:0019724//B cell mediated immunity;GO:0015031//protein transport;GO:0043410//positive regulation of MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0032722//positive regulation of chemokine production;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0030888//regulation of B cell proliferation;GO:0006693//prostaglandin metabolic process;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0051084//'de novo' posttranslational protein folding;GO:0043368//positive T cell selection;GO:0002468//dendritic cell antigen processing and presentation;GO:0010934//macrophage cytokine production;GO:0065003;GO:0002828//regulation of type 2 immune response;GO:0002478" gi|110624770|ref|NP_001036070.1|/1.12564e-151/H-2 class II histocompatibility antigen gamma chain isoform 1 [Mus musculus] 140781 6054 217.2966667 126.0866667 -0.785250321 Down 0.793147542 Myh7 "myosin, heavy polypeptide 7, cardiac muscle, beta" K17751|1|0.0|3319|mmu:140781|myosin heavy chain 6/7 - - - - 239017 3449 80.43333333 45.14333333 -0.83328056 Down 0.791464515 Ogdhl oxoglutarate dehydrogenase-like K00164|1|0.0|2065|mmu:239017|2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] - "GO:0016903//oxidoreductase activity, acting on the aldehyde or oxo group of donors;GO:0019842//vitamin binding" GO:0009060//aerobic respiration "gi|124487483|ref|NP_001074599.1|/0/2-oxoglutarate dehydrogenase-like, mitochondrial [Mus musculus]" 15129 630 90.66333333 51.48 -0.816507151 Down 0.791144834 Hbb-b1 "hemoglobin, beta adult major chain" K13823|1|2e-80|300|mmu:15129|hemoglobin subunit beta GO:0043234//protein complex GO:0046906//tetrapyrrole binding;GO:0022892//substrate-specific transporter activity;GO:0046914//transition metal ion binding GO:0001932//regulation of protein phosphorylation;GO:0015669;GO:0030218//erythrocyte differentiation gi|498752597|ref|NP_001265090.1|/1.74367e-79/hemoglobin subunit beta-1 [Mus musculus] 240328 3297 1.053333333 5.04 2.258461676 Up 0.790590094 F830016B08Rik RIKEN cDNA F830016B08 gene K17072|1|4e-96|355|mmu:432555|interferon gamma inducible protein 47 - - - gi|197382616|ref|NP_001094945.1|/0/interferon-inducible GTPase-like [Mus musculus] 100702 4329 23.45 43.14 0.879438254 Up 0.788907067 Gbp6 guanylate binding protein 6 K17339|1|1e-17|95.5|hro:HELRODRAFT_73066|atlastin [EC:3.6.5.-] GO:0031982//vesicle;GO:0020003//symbiont-containing vacuole - GO:0001562//response to protozoan;GO:0042742//defense response to bacterium;GO:0034341//response to interferon-gamma;GO:0032496//response to lipopolysaccharide;GO:0035456//response to interferon-beta;GO:0051702//interaction with symbiont gi|755512157|ref|XP_011247688.1|/0/PREDICTED: guanylate binding protein 6 isoform X3 [Mus musculus] 102466887 97 0.01 2.116666667 7.725650281 Up 0.787844597 Mir8116 microRNA 8116 - - - - - 109801 1477.05 56.62 98.32333333 0.796222077 Up 0.787562526 Glo1 glyoxalase 1 K01759|1|5e-105|384|mmu:109801|lactoylglutathione lyase [EC:4.4.1.5] - GO:0043169//cation binding;GO:0016846//carbon-sulfur lyase activity;GO:0043169//cation binding;GO:0016846//carbon-sulfur lyase activity GO:0006915//apoptotic process;GO:0006790//sulfur compound metabolic process;GO:0006081//cellular aldehyde metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0006790//sulfur compound metabolic process;GO:0006081//cellular aldehyde metabolic process;GO:0006366//transcription from RNA polymerase II promoter gi|165932331|ref|NP_079650.3|/4.54118e-104/lactoylglutathione lyase [Mus musculus] 102465576 60 2.046666667 0.01 -7.677132345 Down 0.782645079 Mir6954 microRNA 6954 - - - - - 102465635 60 2.046666667 0.01 -7.677132345 Down 0.782645079 Mir7050 microRNA 7050 - - - - - 100526466 83 2.046666667 0.01 -7.677132345 Down 0.782645079 Mir3060 microRNA 3060 - - - - - 16763 2992 1.156666667 4.923333333 2.089662258 Up 0.781168904 Lad1 ladinin K04573|1|2e-13|81.3|fab:101815677|neurofilament medium polypeptide (neurofilament 3);K04574|4|2e-13|81.3|mcf:102145883|neurofilament heavy polypeptide GO:0005578//proteinaceous extracellular matrix - - gi|31981555|ref|NP_598425.2|/0/ladinin-1 [Mus musculus] 268860 4617.13 5.18 11.63 1.166827094 Up 0.780557749 Abat 4-aminobutyrate aminotransferase K13524|1|0.0|1024|mmu:268860|4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22] GO:0043234//protein complex;GO:0042995//cell projection;GO:0044429;GO:0043234//protein complex;GO:0042995//cell projection;GO:0044429 GO:0043168//anion binding;GO:0008483//transaminase activity;GO:0042802//identical protein binding;GO:0019899//enzyme binding;GO:0043168//anion binding;GO:0008483//transaminase activity;GO:0042802//identical protein binding;GO:0019899//enzyme binding GO:0007618//mating;GO:0010038//response to metal ion;GO:0097305//response to alcohol;GO:0042133//neurotransmitter metabolic process;GO:0008217//regulation of blood pressure;GO:0014070//response to organic cyclic compound;GO:0009063//cellular amino acid catabolic process;GO:0030534//adult behavior;GO:0007618//mating;GO:0010038//response to metal ion;GO:0097305//response to alcohol;GO:0042133//neurotransmitter metabolic process;GO:0008217//regulation of blood pressure;GO:0014070//response to organic cyclic compound;GO:0009063//cellular amino acid catabolic process;GO:0030534//adult behavior "gi|148664876|gb|EDK97292.1|/0/4-aminobutyrate aminotransferase, isoform CRA_c, partial [Mus musculus]" 74488 5323 4.19 0.83 -2.335767002 Down 0.778573846 Lrrc15 leucine rich repeat containing 15 K13023|1|0.0|851|mcc:707574|carboxypeptidase N regulatory subunit;K06260|4|7e-81|305|gga:100857508|platelet glycoprotein V GO:0031224//intrinsic component of membrane - GO:0044763 gi|58037377|ref|NP_083249.1|/0/leucine-rich repeat-containing protein 15 precursor [Mus musculus] 18124 4032.66 13.50666667 6.403333333 -1.076776655 Down 0.777849863 Nr4a3 "nuclear receptor subfamily 4, group A, member 3" K08559|1|0.0|1027|mmu:18124|nuclear receptor subfamily 4 group A member 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0038023//signaling receptor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0038023//signaling receptor activity;GO:0003677//DNA binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0021543//pallium development;GO:0060004//reflex;GO:0051726//regulation of cell cycle;GO:0043065//positive regulation of apoptotic process;GO:0007165//signal transduction;GO:0006935//chemotaxis;GO:0042471//ear morphogenesis;GO:0035239//tube morphogenesis;GO:0006950//response to stress;GO:0009725//response to hormone;GO:0001704//formation of primary germ layer;GO:0050905//neuromuscular process;GO:0006366//transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0009755//hormone-mediated signaling pathway;GO:0021543//pallium development;GO:0060004//reflex;GO:0051726//regulation of cell cycle;GO:0043065//positive regulation of apoptotic process;GO:0006935//chemotaxis;GO:0042471//ear morphogenesis;GO:0035239//tube morphogenesis;GO:0006950//response to stress;GO:0001704//formation of primary germ layer;GO:0050905//neuromuscular process gi|815890829|ref|NP_001294918.1|/8.46062e-180/nuclear receptor subfamily 4 group A member 3 isoform 2 [Mus musculus] 100217442 107 0.01 1.993333333 7.639039173 Up 0.777737034 Snora30 "small nucleolar RNA, H/ACA box 30" - - - - - 100217440 62 1.986666667 0.01 -7.63420602 Down 0.777727632 Snora61 "small nucleolar RNA, H/ACA box 61" - - - - - 102466844 63 10.83 20.93666667 0.950998526 Up 0.776777991 Mir7674 microRNA 7674 - - - - - 14960 1084 41.61 70.95333333 0.769940174 Up 0.776298469 H2-Aa "histocompatibility 2, class II antigen A, alpha" "K06752|1|2e-136|488|mmu:14960|major histocompatibility complex, class II" GO:0031224//intrinsic component of membrane;GO:0000323//lytic vacuole;GO:0042611;GO:0009986//cell surface GO:0046983//protein dimerization activity;GO:0003823//antigen binding GO:0002478;GO:0030217//T cell differentiation;GO:0051384//response to glucocorticoid;GO:0034097//response to cytokine;GO:0042098//T cell proliferation "gi|31981716|ref|NP_034508.2|/1.27876e-135/histocompatibility 2, class II antigen A, alpha precursor [Mus musculus]" 71889 3884 14.33333333 6.97 -1.040143598 Down 0.776054007 Epn3 epsin 3 K12471|1|0.0|1019|mmu:71889|epsin GO:0031410//cytoplasmic vesicle GO:0005488//binding - "gi|148683978|gb|EDL15925.1|/0/epsin 3, isoform CRA_b, partial [Mus musculus]" 100316814 79 1.956666667 0.01 -7.612254192 Down 0.775029147 Mir1306 microRNA 1306 K18419|1|1e-07|57.0|ocu:100351620|microprocessor complex subunit DGCR8 - - - "gi|149019784|gb|EDL77932.1|/1.15916e-06/DiGeorge syndrome critical region gene 8 (predicted), isoform CRA_b [Rattus norvegicus]" 14869 785 19.91 10.31333333 -0.948982525 Down 0.774258152 Gstp2 "glutathione S-transferase, pi 2" K00799|1|3e-120|433|mmu:14869|glutathione S-transferase [EC:2.5.1.18] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane "GO:0030234//enzyme regulator activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0072341//modified amino acid binding;GO:0019901//protein kinase binding" GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0032868//response to insulin;GO:0006915//apoptotic process;GO:0032611//interleukin-1 beta production;GO:0021782//glial cell development;GO:0051384//response to glucocorticoid;GO:0031668//cellular response to extracellular stimulus;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0006979//response to oxidative stress;GO:0032682//negative regulation of chemokine production;GO:0002526//acute inflammatory response;GO:0070265//necrotic cell death;GO:0070849//response to epidermal growth factor;GO:0032872//regulation of stress-activated MAPK cascade;GO:0006790//sulfur compound metabolic process;GO:0043407//negative regulation of MAP kinase activity;GO:0001101//response to acid chemical;GO:0043627//response to estrogen;GO:0010038//response to metal ion;GO:0008285//negative regulation of cell proliferation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0033273//response to vitamin;GO:0051354//negative regulation of oxidoreductase activity;GO:0010558;GO:0097305//response to alcohol;GO:0032496//response to lipopolysaccharide;GO:0009887//organ morphogenesis gi|32401425|ref|NP_861461.1|/2.1241e-119/glutathione S-transferase P 2 [Mus musculus] 654432 1368 0.01 1.916666667 7.582455645 Up 0.771663094 Gm7334 B-cell translocation gene 3 pseudogene K14443|1|2e-132|474|mmu:12228|protein Tob/BTG GO:0044424 - GO:0006950//response to stress;GO:0000278//mitotic cell cycle;GO:0008283//cell proliferation gi|6753208|ref|NP_033900.1|/1.59175e-131/protein BTG3 [Mus musculus] 16912 806 7.213333333 14.40666667 0.997998573 Up 0.771061341 Psmb9 "proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)" K02741|1|2e-82|307|mmu:16912|20S proteasome subunit beta 9 [EC:3.4.25.1] - - - - 97114 649 1.076666667 4.54 2.076120633 Up 0.770816879 Hist2h3c2 "histone cluster 2, H3c2" K11254|1|2e-71|270|pps:100972611|histone H4;K11253|4|3e-71|270|dre:100006146|histone H3 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding - gi|27372732|gb|AAO06264.1|/3.72044e-96/histone protein Hist2h3c1 [Mus musculus] 100217428 63 1.913333333 0.01 -7.579944426 Down 0.770807477 Snord57 "small nucleolar RNA, C/D box 57" - - - - - 102466220 62 0.01 1.883333333 7.557144557 Up 0.768278235 Mir7069 microRNA 7069 - - - - - 100217455 62 0.01 1.883333333 7.557144557 Up 0.768278235 Snord49a "small nucleolar RNA, C/D box 49A" - - - - - 70807 2346 8.836666667 17.24333333 0.964464521 Up 0.768268833 Arrdc2 arrestin domain containing 2 "K09364|1|2e-13|80.9|gja:107122555|POU domain transcription factor, class 2" - - GO:0007154//cell communication "gi|148696931|gb|EDL28878.1|/0/arrestin domain containing 2, isoform CRA_b, partial [Mus musculus]" 353374 62 1.856666667 0.01 -7.536571017 Down 0.766604611 Snord61 "small nucleolar RNA, C/D box 61" - - - - - 54378 1510 1.086666667 4.393333333 2.015406501 Up 0.764677122 Cacng6 "calcium channel, voltage-dependent, gamma subunit 6" K04871|1|6e-117|423|mmu:54378|voltage-dependent calcium channel gamma-6 - - - - 12352 1248 0.146666667 2.333333333 3.991779493 Up 0.764583098 Car5a "carbonic anhydrase 5a, mitochondrial" K01672|1|0.0|636|mmu:12352|carbonic anhydrase [EC:4.2.1.1] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0016836//hydro-lyase activity GO:0044237//cellular metabolic process;GO:0006006//glucose metabolic process "gi|112181175|ref|NP_031634.2|/2.7725e-180/carbonic anhydrase 5A, mitochondrial precursor [Mus musculus]" 14972 1669 135.8633333 216.8533333 0.674563464 Up 0.762476964 H2-K1 "histocompatibility 2, K1, K region" "K06751|1|0.0|706|mmu:14972|major histocompatibility complex, class I" - - - - 112407 2693 35.56666667 58.84333333 0.726353204 Up 0.76242055 Egln3 egl-9 family hypoxia-inducible factor 3 K09592|1|5e-173|610|rno:54702|hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0019842//vitamin binding;GO:0046914//transition metal ion binding;GO:0031543//peptidyl-proline dioxygenase activity;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0033554//cellular response to stress;GO:0019471//4-hydroxyproline metabolic process;GO:0006464//cellular protein modification process;GO:0042981//regulation of apoptotic process;GO:0008283//cell proliferation gi|149051230|gb|EDM03403.1|/5.17647e-173/rCG62399 [Rattus norvegicus] 102466817 63 1.813333333 0.01 -7.502500341 Down 0.761781188 Mir7211 microRNA 7211 - - - - - 27211 89 0.01 1.803333333 7.494522283 Up 0.760822144 Snord35a "small nucleolar RNA, C/D box 35A" - - - - - 17318 3347.56 4.716666667 10.17666667 1.109425536 Up 0.760671706 Mid1 midline 1 K08285|1|0.0|877|mmu:17318|midline 1 [EC:2.3.2.27] GO:0005874//microtubule GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003824//catalytic activity GO:0007019//microtubule depolymerization;GO:0032872//regulation of stress-activated MAPK cascade;GO:0007275//multicellular organism development gi|594191002|ref|NP_001277441.1|/0/E3 ubiquitin-protein ligase Midline-1 isoform 4 [Mus musculus] 102466208 63 1.786666667 0.01 -7.48112669 Down 0.759919516 Mir6924 microRNA 6924 - - - - - 102465624 65 1.78 0.01 -7.475733431 Down 0.759073301 Mir7031 microRNA 7031 - - - - - 20271 8334.21 88.90666667 55.42333333 -0.681798122 Down 0.756647486 Scn5a "sodium channel, voltage-gated, type V, alpha" K04838|1|0.0|3639|mmu:20271|voltage-gated sodium channel type V alpha GO:0044291//cell-cell contact zone;GO:0043231//intracellular membrane-bounded organelle;GO:0042383//sarcolemma;GO:0034703//cation channel complex;GO:0005887//integral component of plasma membrane;GO:0044291//cell-cell contact zone;GO:0043231//intracellular membrane-bounded organelle;GO:0042383//sarcolemma;GO:0034703//cation channel complex;GO:0005887//integral component of plasma membrane GO:0019838//growth factor binding;GO:0086006//voltage-gated sodium channel activity involved in cardiac muscle cell action potential;GO:0008092//cytoskeletal protein binding;GO:0019838//growth factor binding;GO:0086006//voltage-gated sodium channel activity involved in cardiac muscle cell action potential;GO:0008092//cytoskeletal protein binding GO:0002027//regulation of heart rate;GO:0086010//membrane depolarization during action potential;GO:0010033//response to organic substance;GO:0051592//response to calcium ion;GO:0042476//odontogenesis;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0030900//forebrain development;GO:0060306//regulation of membrane repolarization;GO:0003254//regulation of membrane depolarization;GO:0014877;GO:0008284//positive regulation of cell proliferation;GO:0086065//cell communication involved in cardiac conduction;GO:0003205//cardiac chamber development;GO:0022037//metencephalon development;GO:0002028//regulation of sodium ion transport;GO:0002027//regulation of heart rate;GO:0086010//membrane depolarization during action potential;GO:0010033//response to organic substance;GO:0051592//response to calcium ion;GO:0042476//odontogenesis;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0030900//forebrain development;GO:0060306//regulation of membrane repolarization;GO:0003254//regulation of membrane depolarization;GO:0014877;GO:0008284//positive regulation of cell proliferation;GO:0086065//cell communication involved in cardiac conduction;GO:0003205//cardiac chamber development;GO:0022037//metencephalon development;GO:0002028//regulation of sodium ion transport gi|568963585|ref|XP_006512057.1|/0/PREDICTED: sodium channel protein type 5 subunit alpha isoform X3 [Mus musculus] 100526469 67 33.74333333 55.17333333 0.709368647 Up 0.75646884 Mir3064 microRNA 3064 K12823|1|6e-06|51.2|myb:102246453|ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13] - - - - 102465622 64 0.01 1.746666667 7.448460501 Up 0.756431231 Mir7028 microRNA 7028 - - - - - 271424 2305 17.21 9.243333333 -0.896761982 Down 0.756412426 Ip6k3 inositol hexaphosphate kinase 3 K07756|1|0.0|746|mmu:271424|inositol-hexakisphosphate 5-kinase [EC:2.7.4.21] GO:0043231//intracellular membrane-bounded organelle GO:0051766//inositol trisphosphate kinase activity;GO:0032550;GO:0000828//inositol hexakisphosphate kinase activity GO:0006464//cellular protein modification process;GO:0043647//inositol phosphate metabolic process;GO:0006650//glycerophospholipid metabolic process "gi|148690586|gb|EDL22533.1|/0/inositol hexaphosphate kinase 3, isoform CRA_a, partial [Mus musculus]" 665433 552 7.71 3.24 -1.250737047 Down 0.75611155 Hist1h2ao "histone cluster 1, H2ao" K11251|1|2e-54|213|ocu:100348744|histone H2A;K11254|4|3e-54|213|cfa:488260|histone H4 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|655839886|ref|XP_002714260.2|/1.43845e-53/PREDICTED: histone H2A type 1-like [Oryctolagus cuniculus] 20846 5178.2 13.71 24.05333333 0.811008267 Up 0.755585016 Stat1 signal transducer and activator of transcription 1 K11220|1|0.0|1504|mmu:20846|signal transducer and activator of transcription 1 GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0031981//nuclear lumen;GO:0043005//neuron projection "GO:0060089;GO:0046872//metal ion binding;GO:0043566//structure-specific DNA binding;GO:0048020//CCR chemokine receptor binding;GO:0042802//identical protein binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0060089;GO:0046872//metal ion binding;GO:0043566//structure-specific DNA binding;GO:0048020//CCR chemokine receptor binding;GO:0042802//identical protein binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0060089;GO:0046872//metal ion binding;GO:0043566//structure-specific DNA binding;GO:0048020//CCR chemokine receptor binding;GO:0042802//identical protein binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0032813//tumor necrosis factor receptor superfamily binding" GO:0001935//endothelial cell proliferation;GO:0035456//response to interferon-beta;GO:0032868//response to insulin;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0035295//tube development;GO:0031667//response to nutrient levels;GO:0043331//response to dsRNA;GO:0019221//cytokine-mediated signaling pathway;GO:0016477//cell migration;GO:0012502//induction of programmed cell death;GO:0000302//response to reactive oxygen species;GO:0002237//response to molecule of bacterial origin;GO:0046683//response to organophosphorus;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0003013//circulatory system process;GO:0001935//endothelial cell proliferation;GO:0035456//response to interferon-beta;GO:0032868//response to insulin;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0035295//tube development;GO:0031667//response to nutrient levels;GO:0043331//response to dsRNA;GO:0019221//cytokine-mediated signaling pathway;GO:0016477//cell migration;GO:0012502//induction of programmed cell death;GO:0000302//response to reactive oxygen species;GO:0002237//response to molecule of bacterial origin;GO:0046683//response to organophosphorus;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0003013//circulatory system process;GO:0001935//endothelial cell proliferation;GO:0035456//response to interferon-beta;GO:0032868//response to insulin;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0035295//tube development;GO:0031667//response to nutrient levels;GO:0043331//response to dsRNA;GO:0019221//cytokine-mediated signaling pathway;GO:0016477//cell migration;GO:0012502//induction of programmed cell death;GO:0000302//response to reactive oxygen species;GO:0002237//response to molecule of bacterial origin;GO:0046683//response to organophosphorus;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0003013//circulatory system process "gi|148667548|gb|EDK99964.1|/0/signal transducer and activator of transcription 1, isoform CRA_a, partial [Mus musculus]" 67866 1169 15.46 26.65 0.785595214 Up 0.755387566 Wfdc1 WAP four-disulfide core domain 1 - GO:0044421 GO:0004866//endopeptidase inhibitor activity GO:0043627//response to estrogen;GO:0008285//negative regulation of cell proliferation;GO:0016049//cell growth;GO:0051346//negative regulation of hydrolase activity "gi|148679665|gb|EDL11612.1|/6.70404e-125/WAP four-disulfide core domain 1, isoform CRA_c, partial [Mus musculus]" 11459 1481.27 461.88 297.71 -0.633610395 Down 0.753685735 Acta1 "actin, alpha 1, skeletal muscle" "K10354|1|0.0|775|cge:100768972|actin, alpha skeletal muscle" GO:0031988//membrane-bounded vesicle;GO:0032991//macromolecular complex;GO:0030016//myofibril;GO:0032432//actin filament bundle;GO:0031988//membrane-bounded vesicle;GO:0032991//macromolecular complex;GO:0030016//myofibril;GO:0032432//actin filament bundle GO:0008092//cytoskeletal protein binding;GO:0032550;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0032550;GO:0005198//structural molecule activity GO:0043501//skeletal muscle adaptation;GO:0010038//response to metal ion;GO:0009725//response to hormone;GO:0007015//actin filament organization;GO:0040007//growth;GO:0007519//skeletal muscle tissue development;GO:0006936//muscle contraction;GO:0009605//response to external stimulus;GO:0043501//skeletal muscle adaptation;GO:0010038//response to metal ion;GO:0009725//response to hormone;GO:0007015//actin filament organization;GO:0040007//growth;GO:0007519//skeletal muscle tissue development;GO:0006936//muscle contraction;GO:0009605//response to external stimulus "gi|149043182|gb|EDL96714.1|/0/actin, alpha 1, skeletal muscle, isoform CRA_a [Rattus norvegicus]" 100217453 91 0.01 1.72 7.426264755 Up 0.753460077 Snord16a "small nucleolar RNA, C/D box 16A" - - - - - 387160 64 1.72 0.01 -7.426264755 Down 0.753460077 Mir142 microRNA 142 - - - - - 26897 1559 11.87 21.02666667 0.824900224 Up 0.751438565 Acot1 acyl-CoA thioesterase 1 K01068|1|0.0|781|mmu:26897|acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2] GO:0044429 GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0005515//protein binding GO:0000038//very long-chain fatty acid metabolic process;GO:0009719;GO:0042221//response to chemical;GO:0009991//response to extracellular stimulus;GO:0006732;GO:0006950//response to stress gi|6753550|ref|NP_036136.1|/0/acyl-coenzyme A thioesterase 1 [Mus musculus] 104366 117 0.603333333 3.28 2.442668618 Up 0.750695776 Snora64 "small nucleolar RNA, H/ACA box 64" - - - - - 102465656 92 0.01 1.686666667 7.398031074 Up 0.750620557 Mir7082 microRNA 7082 - - - - - 104795666 88 1.67 0.01 -7.383704292 Down 0.748749483 Gm24572 "predicted gene, 24572" - - - - - 18115 3668.37 270.3666667 175.9666667 -0.619615128 Down 0.748279364 Nnt nicotinamide nucleotide transhydrogenase K00323|1|0.0|1974|rno:310378|NAD(P) transhydrogenase [EC:1.6.1.2] GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane GO:0008746//NAD(P)+ transhydrogenase activity;GO:0000166//nucleotide binding GO:0044237//cellular metabolic process;GO:0006818//hydrogen transport;GO:0044710 "gi|819023691|ref|NP_001295435.1|/0/NAD(P) transhydrogenase, mitochondrial isoform 2 [Mus musculus] " 102466803 65 1.66 0.01 -7.375039431 Down 0.747658806 Mir7086 microRNA 7086 - - - - - 23833 531 5.96 11.81666667 0.987438891 Up 0.746511715 Cd52 CD52 antigen K06488|1|7e-11|68.6|mmu:23833|CDW52 antigen - - - gi|74212922|dbj|BAE33405.1|/5.04898e-10/unnamed protein product [Mus musculus] 78354 881 6.15 12.07333333 0.97316573 Up 0.746107413 2210407C18Rik RIKEN cDNA 2210407C18 gene "K05302|1|3e-10|68.2|hgl:101722735|N-lysine methyltransferase SETD6 [EC:2.1.1.-];K03985|2|4e-07|57.8|gja:107115687|plasminogen activator, urokinase receptor" - - GO:0048771//tissue remodeling gi|253970410|ref|NP_653127.2|/1.00956e-118/epithelial progenitor 1 precursor [Mus musculus] 233199 3624 5.963333333 2.27 -1.393426684 Down 0.744499605 Mybpc2 "myosin binding protein C, fast-type" "K12558|1|0.0|2116|mmu:233199|myosin-binding protein C, fast-type" GO:0016459//myosin complex GO:0005198//structural molecule activity GO:0022610;GO:0003012//muscle system process "gi|268370244|ref|NP_666301.2|/0/myosin-binding protein C, fast-type [Mus musculus]" 67888 1764 15.48666667 26.12666667 0.754496419 Up 0.744292753 Tmem100 transmembrane protein 100 - GO:0044444//cytoplasmic part - GO:0043009//chordate embryonic development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0060837//blood vessel endothelial cell differentiation gi|148683933|gb|EDL15880.1|/1.53848e-39/transmembrane protein 100 [Mus musculus] 55987 3506 18.34666667 10.38 -0.821711526 Down 0.743822633 Cpxm2 carboxypeptidase X 2 (M14 family) K08639|1|0.0|1383|mmu:55987|carboxypeptidase X2 GO:0044421 GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0022610;GO:0019538//protein metabolic process gi|229092758|ref|NP_061355.3|/0/inactive carboxypeptidase-like protein X2 precursor [Mus musculus] 15370 2534 29.44666667 17.69333333 -0.734898462 Down 0.743333709 Nr4a1 "nuclear receptor subfamily 4, group A, member 1" K04465|1|0.0|1024|mmu:15370|nuclear receptor subfamily 4 group A member 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0038023//signaling receptor activity;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0003677//DNA binding" GO:0071363//cellular response to growth factor stimulus;GO:0043542//endothelial cell migration;GO:0006366//transcription from RNA polymerase II promoter;GO:0001935//endothelial cell proliferation;GO:0009755//hormone-mediated signaling pathway;GO:0002040//sprouting angiogenesis;GO:0006915//apoptotic process;GO:0007519//skeletal muscle tissue development;GO:0012502//induction of programmed cell death gi|568991389|ref|XP_006520518.1|/0/PREDICTED: nuclear receptor subfamily 4 group A member 1 isoform X2 [Mus musculus] 102466218 62 0.01 1.6 7.321928095 Up 0.741227575 Mir7054 microRNA 7054 - - - - - 723889 66 0.01 1.586666667 7.309855263 Up 0.740146301 Mir378a microRNA 378a - - - - - 631323 2702 1.266666667 4.266666667 1.752072487 Up 0.739647975 Gm12250 predicted gene 12250 K17072|1|1e-118|430|mmu:432555|interferon gamma inducible protein 47 - - - "gi|148675817|gb|EDL07764.1|/0/mCG20690, partial [Mus musculus]" 223513 1762 46.93666667 29.61333333 -0.664468496 Down 0.738312836 Abra actin-binding Rho activating protein K15271|1|1e-15|87.4|pxy:105391464|ATP-dependent DNA helicase HFM1/MER3 [EC:3.6.4.12];K15430|2|5e-06|55.5|apla:101791890|tRNA (guanine10-N2)-methyltransferase [EC:2.1.1.214] GO:0016020//membrane;GO:0030016//myofibril;GO:0005856//cytoskeleton GO:0003712//transcription cofactor activity;GO:0008092//cytoskeletal protein binding GO:0007266//Rho protein signal transduction;GO:0006366//transcription from RNA polymerase II promoter;GO:0044093;GO:0006606//protein import into nucleus gi|30425194|ref|NP_780665.1|/0/actin-binding Rho-activating protein [Mus musculus] 17901 854.18 47.16333333 72.81666667 0.626603014 Up 0.737457219 Myl1 "myosin, light polypeptide 1" K05738|1|1e-87|303|nle:100595875|myosin light chain 1 GO:0015629//actin cytoskeleton;GO:0043292//contractile fiber;GO:0043292//contractile fiber;GO:0015629//actin cytoskeleton GO:0046872//metal ion binding GO:0006941//striated muscle contraction;GO:0006941//striated muscle contraction "gi|164664497|ref|NP_001106858.1|/5.28322e-79/myosin light chain 1/3, skeletal muscle isoform isoform 3f [Mus musculus]" 102465586 67 0.01 1.536666667 7.26366044 Up 0.734824552 Mir6970 microRNA 6970 - - - - - 67629 1349 7.966666667 14.31666667 0.845647513 Up 0.734298018 Spc24 "SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)" "K11549|1|2e-99|365|mmu:67629|kinetochore protein Spc24, animal type" GO:0000776//kinetochore;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding GO:0007067//mitotic nuclear division gi|21312862|ref|NP_080558.1|/1.74191e-98/kinetochore protein Spc24 [Mus musculus] 24117 2242 1.856666667 5.12 1.463428983 Up 0.733696265 Wif1 Wnt inhibitory factor 1 K01691|1|0.0|768|mmu:24117|WNT inhibitory factor 1 - GO:0005515//protein binding GO:0016055//Wnt signaling pathway;GO:0045444//fat cell differentiation gi|6755999|ref|NP_036045.1|/0/wnt inhibitory factor 1 precursor [Mus musculus] 387235 68 1.526666667 0.01 -7.254241287 Down 0.733677461 Mir125a microRNA 125a - - - - - 723882 121 0.01 1.526666667 7.254241287 Up 0.733677461 Mir546 microRNA 546 - - - - - 100127111 126 0.57 2.936666667 2.365145694 Up 0.733141525 Snord22 "small nucleolar RNA, C/D box 22" - - - - - 100039796 2816 3.54 7.6 1.102250058 Up 0.732426943 Tgtp2 T cell specific GTPase 2 K17072|1|3e-155|551|mmu:432555|interferon gamma inducible protein 47 - GO:0032550 GO:0035456//response to interferon-beta "gi|148701833|gb|EDL33780.1|/0/T-cell specific GTPase, isoform CRA_a, partial [Mus musculus]" 16007 2028 65.38333333 42.69 -0.615024767 Down 0.732201286 Cyr61 cysteine rich protein 61 K06829|1|0.0|695|mmu:16007|cysteine rich protein 61 GO:0031012//extracellular matrix GO:0005102//receptor binding;GO:0005539//glycosaminoglycan binding;GO:0019838//growth factor binding GO:0010810//regulation of cell-substrate adhesion;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0043062//extracellular structure organization;GO:0016337//single organismal cell-cell adhesion;GO:0043408//regulation of MAPK cascade;GO:0016049//cell growth;GO:0051094//positive regulation of developmental process;GO:0016477//cell migration;GO:0046513//ceramide biosynthetic process;GO:0001934//positive regulation of protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0003171//atrioventricular valve development;GO:0001649//osteoblast differentiation;GO:0003231//cardiac ventricle development;GO:0003209//cardiac atrium morphogenesis;GO:0042221//response to chemical;GO:0010517//regulation of phospholipase activity;GO:0001525//angiogenesis;GO:0048568//embryonic organ development gi|6753594|ref|NP_034646.1|/0/protein CYR61 precursor [Mus musculus] 387230 70 1.513333333 0.01 -7.241585987 Down 0.731449095 Mir99b microRNA 99b - - - - gi|594084771|ref|XP_006065940.1|/8.65212e-06/PREDICTED: basic salivary proline-rich protein 2-like isoform X2 [Bubalus bubalis] 100499523 102 1.493333333 0.01 -7.222392421 Down 0.72902328 Mir3471-2 microRNA 3471-2 - - - - gi|148676209|gb|EDL08156.1|/1.34796e-07/mCG141277 [Mus musculus] 20716 2085 16.54333333 26.60666667 0.685537824 Up 0.727387265 Serpina3n "serine (or cysteine) peptidase inhibitor, clade A, member 3N" "K04525|1|0.0|791|mmu:20716|serpin peptidase inhibitor, clade A" - - - gi|130503301|ref|NP_033278.2|/0/serine protease inhibitor A3N precursor [Mus musculus] 11606 1856 38.58333333 24.75 -0.640549262 Down 0.726089736 Agt "angiotensinogen (serpin peptidase inhibitor, clade A, member 8)" K09821|1|0.0|959|mmu:11606|angiotensinogen - - - gi|113461998|ref|NP_031454.3|/0/angiotensinogen [Mus musculus] 387145 73 4.086666667 1.316666667 -1.634034421 Down 0.72562902 Mir126a microRNA 126a - - - - - 100216537 73 3.99 1.283333333 -1.636492801 Down 0.722883523 Snord104 "small nucleolar RNA, C/D box 104" - - - - - 76905 1372 51.59333333 77.21666667 0.581727618 Up 0.722817707 Lrg1 leucine-rich alpha-2-glycoprotein 1 K17256|1|3e-20|102|phd:102321773|insulin-like growth factor-binding protein complex acid labile subunit;K13023|3|3e-19|99.0|asn:102370171|carboxypeptidase N regulatory subunit GO:0044421 - GO:0045444//fat cell differentiation gi|16418335|ref|NP_084072.1|/3.00033e-154/leucine-rich alpha-2-glycoprotein precursor [Mus musculus] 387163 70 0.01 1.433333333 7.163230349 Up 0.72176464 Mir145a microRNA 145a - - - - - 100316700 70 0.01 1.433333333 7.163230349 Up 0.72176464 Mir1949 microRNA 1949 - - - - - 100216539 70 0.01 1.433333333 7.163230349 Up 0.72176464 Snord4a "small nucleolar RNA, C/D box 4A" - - - - - 102465545 70 0.01 1.433333333 7.163230349 Up 0.72176464 Mir6905 microRNA 6905 - - - - - 19881 1526 20.62666667 12.62333333 -0.708417776 Down 0.720730377 Rom1 rod outer segment membrane protein 1 K17344|1|5e-134|480|mmu:19881|rod outer segment membrane protein 1 GO:0016020//membrane;GO:0001750//photoreceptor outer segment - - gi|256665253|ref|NP_033099.3|/4.38808e-133/rod outer segment membrane protein 1 [Mus musculus] 16913 1223 11.89333333 19.54 0.716277353 Up 0.720222648 Psmb8 "proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)" K02740|1|1e-159|565|mmu:16913|20S proteasome subunit beta 8 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity GO:0030154//cell differentiation;GO:0002376//immune system process;GO:0006508//proteolysis gi|532035172|ref|XP_005360485.1|/7.61789e-159/PREDICTED: proteasome subunit beta type-8 [Microtus ochrogaster] 12709 1478 42.94333333 64.41 0.584850512 Up 0.719555079 Ckb "creatine kinase, brain" K00933|1|0.0|745|mmu:12709|creatine kinase [EC:2.7.3.2] GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0032550;GO:0016301//kinase activity GO:0007417//central nervous system development;GO:0006599;GO:0030320//cellular monovalent inorganic anion homeostasis gi|10946574|ref|NP_067248.1|/0/creatine kinase B-type [Mus musculus] 17930 4953 261.8133333 179.8666667 -0.541610724 Down 0.718426793 Myom2 myomesin 2 K12567|1|1e-71|275|sko:100367237|titin [EC:2.7.11.1] GO:0031672//A band GO:0005198//structural molecule activity GO:0003012//muscle system process gi|568953176|ref|XP_006508790.1|/0/PREDICTED: myomesin-2 isoform X2 [Mus musculus] 19871 71 1.396666667 0.01 -7.125843933 Down 0.71782504 Rnu73b U73B small nuclear RNA - - - - - 723960 107 1.4 0.01 -7.129283017 Down 0.71782504 Mir24-2 microRNA 24-2 - - - - - 100526508 104 0.01 1.39 7.118941073 Up 0.716583926 Mir3102 microRNA 3102 - - - - - 21354 2950 7.656666667 13.29333333 0.795914553 Up 0.715878747 Tap1 "transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)" "K05653|1|0.0|1233|mmu:21354|ATP-binding cassette, subfamily B (MDR/TAP), member 2" - - - gi|239835765|ref|NP_038711.2|/0/antigen peptide transporter 1 isoform 1 [Mus musculus] 15107 1801 164.75 237.5133333 0.527730039 Up 0.71360337 Hadh hydroxyacyl-Coenzyme A dehydrogenase K00022|1|2e-168|594|mmu:15107|3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] GO:0031981//nuclear lumen;GO:0019866//organelle inner membrane;GO:0044429 "GO:0048037//cofactor binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0043168//anion binding;GO:0036094//small molecule binding" GO:0009062//fatty acid catabolic process;GO:0050796//regulation of insulin secretion;GO:0043434//response to peptide hormone "gi|111038118|ref|NP_032238.2|/1.99345e-167/hydroxyacyl-coenzyme A dehydrogenase, mitochondrial precursor [Mus musculus]" 100628601 71 0.01 1.36 7.087462841 Up 0.712794765 Mir5132 microRNA 5132 - - - - - 74747 1685 42.54 62.96333333 0.565691887 Up 0.712531498 Ddit4 DNA-damage-inducible transcript 4 K08270|1|5e-109|397|mmu:74747|DNA-damage-inducible transcript 4 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005515//protein binding GO:0032984;GO:0007417//central nervous system development;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009968//negative regulation of signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001933//negative regulation of protein phosphorylation;GO:0002252;GO:0006096//glycolytic process;GO:0010942//positive regulation of cell death;GO:0030154//cell differentiation;GO:0016477//cell migration gi|21312868|ref|NP_083359.1|/4.28985e-108/DNA damage-inducible transcript 4 protein [Mus musculus] 12070 939 3.106666667 6.55 1.076127452 Up 0.711967355 Ngfrap1 nerve growth factor receptor (TNFRSF16) associated protein 1 K12465|1|5e-52|182|ptr:465780|nerve growth factor receptor-associated protein 1 - - - - 12521 1818.49 4.196666667 8.23 0.971648553 Up 0.711694686 Cd82 CD82 antigen K06509|1|5e-129|464|mmu:12521|CD82 antigen GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|6671718|ref|NP_031682.1|/4.39314e-128/CD82 antigen [Mus musculus] 102465173 119 4.06 8.04 0.985715774 Up 0.711647674 Mir6340 microRNA 6340 K07891|1|3e-10|65.9|mmu:19334|Ras-related protein Rab-22 - - - "gi|148674705|gb|EDL06652.1|/2.53463e-09/RAB22A, member RAS oncogene family, isoform CRA_b [Mus musculus]" 14999 1284 1.963333333 4.876666667 1.31259023 Up 0.710942495 H2-DMb1 "histocompatibility 2, class II, locus Mb1" "K06752|1|7e-150|532|mmu:14999|major histocompatibility complex, class II" GO:0005770//late endosome;GO:0005764//lysosome;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0042611 GO:0005488//binding GO:0002478;GO:0051084//'de novo' posttranslational protein folding "gi|31981708|ref|NP_034517.2|/5.85152e-149/class II histocompatibility antigen, M beta 1 chain precursor [Mus musculus]" 100037283 962 198.4466667 283.77 0.515970747 Up 0.710237316 Rnaset2a ribonuclease T2A K01166|1|9e-159|561|mmu:68195|ribonuclease T2 [EC:3.1.27.1] GO:0044421;GO:0000323//lytic vacuole;GO:0044432 "GO:0016892//endoribonuclease activity, producing 3'-phosphomonoesters" GO:0016070//RNA metabolic process gi|21311883|ref|NP_080887.1|/7.48514e-158/ribonuclease T2B precursor [Mus musculus] 387216 75 1.32 0.01 -7.044394119 Down 0.707557637 Mir23a microRNA 23a - - - - - 20202 535.19 2.583333333 5.706666667 1.143414486 Up 0.706673812 S100a9 S100 calcium binding protein A9 (calgranulin B) K17274|1|7e-10|65.5|ola:101155699|calpactin-1 light chain;K10384|3|7e-09|62.0|oas:101120628|filaggrin GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0043232;GO:0044421;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0043232;GO:0044421 GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0010556;GO:0006915//apoptotic process;GO:0030036//actin cytoskeleton organization;GO:0010038//response to metal ion;GO:0012502//induction of programmed cell death;GO:0006954//inflammatory response;GO:0097305//response to alcohol;GO:0070486//leukocyte aggregation;GO:0002237//response to molecule of bacterial origin;GO:0030595//leukocyte chemotaxis;GO:0044248;GO:0010556;GO:0006915//apoptotic process;GO:0030036//actin cytoskeleton organization;GO:0010038//response to metal ion;GO:0012502//induction of programmed cell death;GO:0006954//inflammatory response;GO:0097305//response to alcohol;GO:0070486//leukocyte aggregation;GO:0002237//response to molecule of bacterial origin;GO:0030595//leukocyte chemotaxis;GO:0044248 gi|6677837|ref|NP_033140.1|/1.26888e-51/protein S100-A9 [Mus musculus] 11815 2067.51 7.543333333 12.88333333 0.77223183 Up 0.706100267 Apod apolipoprotein D K03098|1|4e-109|398|mmu:11815|apolipoprotein D and lipocalin family protein GO:0043005//neuron projection;GO:0005840//ribosome;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0044421;GO:0043005//neuron projection;GO:0005840//ribosome;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0044421;GO:0043005//neuron projection;GO:0005840//ribosome;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0044421 GO:0032934//sterol binding;GO:0032934//sterol binding;GO:0032934//sterol binding GO:0034439;GO:0009888//tissue development;GO:0042221//response to chemical;GO:0007417//central nervous system development;GO:0009968//negative regulation of signal transduction;GO:0008285//negative regulation of cell proliferation;GO:0001953//negative regulation of cell-matrix adhesion;GO:0031103//axon regeneration;GO:0072678//T cell migration;GO:0019318//hexose metabolic process;GO:0006606//protein import into nucleus;GO:0006979//response to oxidative stress;GO:0032682//negative regulation of chemokine production;GO:0034439;GO:0009888//tissue development;GO:0042221//response to chemical;GO:0007417//central nervous system development;GO:0009968//negative regulation of signal transduction;GO:0008285//negative regulation of cell proliferation;GO:0001953//negative regulation of cell-matrix adhesion;GO:0031103//axon regeneration;GO:0072678//T cell migration;GO:0019318//hexose metabolic process;GO:0006606//protein import into nucleus;GO:0006979//response to oxidative stress;GO:0032682//negative regulation of chemokine production;GO:0034439;GO:0009888//tissue development;GO:0042221//response to chemical;GO:0007417//central nervous system development;GO:0009968//negative regulation of signal transduction;GO:0008285//negative regulation of cell proliferation;GO:0001953//negative regulation of cell-matrix adhesion;GO:0031103//axon regeneration;GO:0072678//T cell migration;GO:0019318//hexose metabolic process;GO:0006606//protein import into nucleus;GO:0006979//response to oxidative stress;GO:0032682//negative regulation of chemokine production gi|75677437|ref|NP_031496.2|/3.27463e-108/apolipoprotein D precursor [Mus musculus] 71699 2242.11 44.88 65.86666667 0.553475865 Up 0.706043853 Slc41a3 "solute carrier family 41, member 3" K15122|1|0.0|812|rno:641603|solute carrier family 41 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity GO:0006811//ion transport;GO:0006811//ion transport gi|82734225|ref|NP_001032570.1|/0/solute carrier family 41 member 3 isoform 2 [Mus musculus] 207215 2518 52.53333333 35.59666667 -0.561490978 Down 0.705225845 Fbxo40 F-box protein 40 K10315|1|0.0|1441|mmu:207215|F-box protein 40 GO:0044424 GO:0046914//transition metal ion binding GO:0032446//protein modification by small protein conjugation gi|82617544|ref|NP_001032398.1|/0/F-box only protein 40 [Mus musculus] 226251 6210.39 148.1366667 103.5966667 -0.515951196 Down 0.705178833 Ablim1 actin-binding LIM protein 1 K07520|1|0.0|1623|mmu:226251|actin-binding LIM protein GO:0005856//cytoskeleton;GO:0005856//cytoskeleton;GO:0005856//cytoskeleton;GO:0005856//cytoskeleton;GO:0005856//cytoskeleton GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0006996//organelle organization;GO:0006935//chemotaxis;GO:0006366//transcription from RNA polymerase II promoter;GO:0006996//organelle organization;GO:0006935//chemotaxis;GO:0006366//transcription from RNA polymerase II promoter;GO:0006996//organelle organization;GO:0050953//sensory perception of light stimulus;GO:0006935//chemotaxis;GO:0009653//anatomical structure morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0006996//organelle organization;GO:0006935//chemotaxis;GO:0006366//transcription from RNA polymerase II promoter;GO:0006996//organelle organization;GO:0006935//chemotaxis;GO:0006366//transcription from RNA polymerase II promoter gi|157057145|ref|NP_848803.3|/0/actin-binding LIM protein 1 isoform 1 [Mus musculus] 102465578 73 1.3 0.01 -7.022367813 Down 0.704953176 Mir6958 microRNA 6958 - - - - - 102465575 68 0.01 1.296666667 7.018663844 Up 0.704953176 Mir6953 microRNA 6953 - - - - - 319158 403 4.733333333 8.853333333 0.903364217 Up 0.704295009 Hist1h4i "histone cluster 1, H4i" K11253|1|5e-41|167|bacu:103011346|histone H3;K11254|2|1e-40|166|ecb:100068166|histone H4 - - - - 231162 974 6.786666667 11.71 0.786966015 Up 0.703674452 Cytl1 cytokine-like 1 - - - GO:0006024//glycosaminoglycan biosynthetic process;GO:0044093;GO:0030154//cell differentiation;GO:0043583//ear development;GO:0006366//transcription from RNA polymerase II promoter gi|124487395|ref|NP_001074575.1|/2.44626e-63/cytokine-like protein 1 precursor [Mus musculus] 668940 6132 17.17 10.67333333 -0.685879232 Down 0.703571026 Myh7b "myosin, heavy chain 7B, cardiac muscle, beta" K10352|1|0.0|3052|mmu:668940|myosin heavy chain - - - - 22223 1156 6.65 3.29 -1.015266757 Down 0.703533416 Uchl1 ubiquitin carboxy-terminal hydrolase L1 K05611|1|7e-125|449|rno:29545|ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12] GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0044297//cell body;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part GO:0032182//ubiquitin-like protein binding;GO:0004175//endopeptidase activity;GO:0008238//exopeptidase activity;GO:0016790//thiolester hydrolase activity;GO:0031690//adrenergic receptor binding GO:0055002//striated muscle cell development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0043405//regulation of MAP kinase activity;GO:0007600//sensory perception;GO:0008088//axo-dendritic transport;GO:0019941//modification-dependent protein catabolic process;GO:0007631//feeding behavior;GO:0070646//protein modification by small protein removal;GO:0008344//adult locomotory behavior "gi|148705826|gb|EDL37773.1|/8.32284e-128/ubiquitin carboxy-terminal hydrolase L1, isoform CRA_b, partial [Mus musculus]" 100499519 126 1.076666667 3.406666667 1.661789126 Up 0.703082102 Mir3470b microRNA 3470b - - - - "gi|148683086|gb|EDL15033.1|/1.09287e-12/mitochondrial ribosomal protein L20, isoform CRA_a [Mus musculus]" 27205 5330 57.32333333 39.12333333 -0.55109321 Down 0.703053894 Podxl podocalyxin-like K06817|1|0.0|733|mmu:27205|podocalyxin-like GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031252//cell leading edge;GO:0036056;GO:0005902//microvillus;GO:0044424 GO:0005488//binding GO:0016477//cell migration;GO:0030033//microvillus assembly;GO:0022409//positive regulation of cell-cell adhesion;GO:0097205//renal filtration;GO:0035148//tube formation;GO:0007162//negative regulation of cell adhesion;GO:0002376//immune system process;GO:0072112//glomerular visceral epithelial cell differentiation gi|6448471|dbj|BAA86912.1|/0/podocalyxin-like protein 1 [Mus musculus] 100628629 74 0.01 1.283333333 7.003752135 Up 0.702329911 Mir5121 microRNA 5121 - - - - - 266793 74 0.01 1.283333333 7.003752135 Up 0.702329911 Snord87 "small nucleolar RNA, C/D box 87" - - - - - 232174 4700 2.943333333 6.15 1.063135473 Up 0.70220768 Cyp26b1 "cytochrome P450, family 26, subfamily b, polypeptide 1" "K12664|1|0.0|989|mmu:232174|cytochrome P450, family 26, subfamily B" GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0046914//transition metal ion binding;GO:0005501//retinoid binding;GO:0004497//monooxygenase activity;GO:0046906//tetrapyrrole binding GO:0001523//retinoid metabolic process;GO:0010467//gene expression;GO:0032526//response to retinoic acid;GO:0045165//cell fate commitment;GO:0035108//limb morphogenesis;GO:0003002//regionalization;GO:0007126//meiotic nuclear division;GO:0016103;GO:0009887//organ morphogenesis;GO:0048232//male gamete generation;GO:0030522//intracellular receptor signaling pathway;GO:0035981 "gi|148666702|gb|EDK99118.1|/0/cytochrome P450, family 26, subfamily b, polypeptide 1, isoform CRA_b, partial [Mus musculus]" 13195 1967 3.306666667 1.016666667 -1.701530878 Down 0.702123058 Ddc dopa decarboxylase K01593|1|0.0|953|mmu:13195|aromatic-L-amino-acid decarboxylase [EC:4.1.1.28] GO:0043005//neuron projection;GO:0044297//cell body;GO:0030136//clathrin-coated vesicle;GO:0043005//neuron projection;GO:0044297//cell body;GO:0030136//clathrin-coated vesicle GO:0005515//protein binding;GO:0031406//carboxylic acid binding;GO:0016831//carboxy-lyase activity;GO:0005515//protein binding;GO:0031406//carboxylic acid binding;GO:0016831//carboxy-lyase activity GO:0070848//response to growth factor;GO:0048511//rhythmic process;GO:0007275//multicellular organism development;GO:0015837//amine transport;GO:0042428//serotonin metabolic process;GO:0042417//dopamine metabolic process;GO:0017085//response to insecticide;GO:0006586;GO:0043279//response to alkaloid;GO:0042493//response to drug;GO:0019752//carboxylic acid metabolic process;GO:0070848//response to growth factor;GO:0048511//rhythmic process;GO:0007275//multicellular organism development;GO:0015837//amine transport;GO:0042428//serotonin metabolic process;GO:0042417//dopamine metabolic process;GO:0017085//response to insecticide;GO:0006586;GO:0043279//response to alkaloid;GO:0042493//response to drug;GO:0019752//carboxylic acid metabolic process gi|148708700|gb|EDL40647.1|/0/dopa decarboxylase [Mus musculus] 70652 2292 31.52666667 20.89666667 -0.593299812 Down 0.701765768 Tmem144 transmembrane protein 144 - GO:0031224//intrinsic component of membrane - - "gi|148683507|gb|EDL15454.1|/0/transmembrane protein 144, isoform CRA_a, partial [Mus musculus]" 66174 1241.89 103.44 72.27666667 -0.517192303 Down 0.700703298 Nudt14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 K08077|1|7e-105|383|mmu:66174|UDP-sugar diphosphatase [EC:3.6.1.45] - - - - 100568459 154 1786.036667 1273.18 -0.488325299 Down 0.700261386 Bc1 brain cytoplasmic RNA 1 - - - - - 11548 3227.76 12.69 19.94 0.651973341 Up 0.700261386 Adra1b "adrenergic receptor, alpha 1b" K04136|1|0.0|1018|mmu:11548|adrenergic receptor alpha-1B GO:0044291//cell-cell contact zone;GO:0016021//integral component of membrane;GO:0042383//sarcolemma;GO:0005635//nuclear envelope;GO:0044291//cell-cell contact zone;GO:0016021//integral component of membrane;GO:0042383//sarcolemma;GO:0005635//nuclear envelope;GO:0044291//cell-cell contact zone;GO:0016021//integral component of membrane;GO:0042383//sarcolemma;GO:0005635//nuclear envelope GO:0046983//protein dimerization activity;GO:0004936//alpha-adrenergic receptor activity;GO:0046983//protein dimerization activity;GO:0004936//alpha-adrenergic receptor activity;GO:0046983//protein dimerization activity;GO:0004936//alpha-adrenergic receptor activity "GO:0014075//response to amine;GO:0003321;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007266//Rho protein signal transduction;GO:0001982;GO:0048771//tissue remodeling;GO:0005980//glycogen catabolic process;GO:0040007//growth;GO:0033500//carbohydrate homeostasis;GO:0007507//heart development;GO:0030534//adult behavior;GO:0007632//visual behavior;GO:0014072//response to isoquinoline alkaloid;GO:0048545//response to steroid hormone;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0000165//MAPK cascade;GO:0003099//positive regulation of the force of heart contraction by chemical signal;GO:0014075//response to amine;GO:0003321;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007266//Rho protein signal transduction;GO:0001982;GO:0048771//tissue remodeling;GO:0005980//glycogen catabolic process;GO:0040007//growth;GO:0033500//carbohydrate homeostasis;GO:0007507//heart development;GO:0030534//adult behavior;GO:0007632//visual behavior;GO:0014072//response to isoquinoline alkaloid;GO:0048545//response to steroid hormone;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0000165//MAPK cascade;GO:0003099//positive regulation of the force of heart contraction by chemical signal;GO:0014075//response to amine;GO:0003321;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007266//Rho protein signal transduction;GO:0001982;GO:0048771//tissue remodeling;GO:0005980//glycogen catabolic process;GO:0040007//growth;GO:0033500//carbohydrate homeostasis;GO:0007507//heart development;GO:0030534//adult behavior;GO:0007632//visual behavior;GO:0014072//response to isoquinoline alkaloid;GO:0048545//response to steroid hormone;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0000165//MAPK cascade;GO:0003099//positive regulation of the force of heart contraction by chemical signal" gi|66792804|ref|NP_031442.2|/0/alpha-1B adrenergic receptor [Mus musculus] 17868 4163 1399.193333 994.19 -0.493001823 Down 0.700054534 Mybpc3 "myosin binding protein C, cardiac" "K12568|1|0.0|2523|mmu:17868|myosin-binding protein C, cardiac-type" GO:0030017//sarcomere GO:0017022//myosin binding GO:0008016//regulation of heart contraction;GO:0031033//myosin filament organization;GO:0030239//myofibril assembly;GO:0009887//organ morphogenesis "gi|134031947|ref|NP_032679.2|/0/myosin-binding protein C, cardiac-type [Mus musculus] " 319177 432 1.893333333 4.596666667 1.279659622 Up 0.700045131 Hist1h2ba "histone cluster 1, H2ba" K11252|1|5e-55|214|mmu:319177|histone H2B - - - - 100503605 639 182.9833333 259.0433333 0.501481206 Up 0.699819474 Hbb-bs "hemoglobin, beta adult s chain" K13823|1|7e-80|298|mmu:100503605|hemoglobin subunit beta GO:0043234//protein complex GO:0046906//tetrapyrrole binding;GO:0022892//substrate-specific transporter activity;GO:0046914//transition metal ion binding GO:0001932//regulation of protein phosphorylation;GO:0015669;GO:0030218//erythrocyte differentiation "gi|31982300|ref|NP_032246.2|/5.12742e-79/hemoglobin, beta adult t chain [Mus musculus]" 100316773 83 0.01 1.263333333 6.981091537 Up 0.699057881 Mir1893 microRNA 1893 - - - - gi|119606377|gb|EAW85971.1|/1.97338e-06/hCG2041374 [Homo sapiens] 102466640 82 13.76333333 8.283333333 -0.732546567 Down 0.699001467 Mir130c microRNA 130c - - - - - 15959 1998 11.03666667 17.55333333 0.669440511 Up 0.698794614 Ifit3 interferon-induced protein with tetratricopeptide repeats 3 K14217|1|1e-78|296|cfa:488947|interferon-induced protein with tetratricopeptide repeats 1 GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding GO:0035456//response to interferon-beta;GO:0006952//defense response;GO:0008283//cell proliferation;GO:0002252;GO:0035455//response to interferon-alpha;GO:0051707//response to other organism;GO:0006915//apoptotic process gi|6754288|ref|NP_034631.1|/0/interferon-induced protein with tetratricopeptide repeats 3 [Mus musculus] 387204 83 6.26 10.85333333 0.793903637 Up 0.697675731 Mir208a microRNA 208a - - - - - 100124438 75 1.25 0.01 -6.965784285 Down 0.69751589 Mir343 microRNA 343 - - - - - 100628602 77 1.253333333 0.01 -6.969626351 Down 0.69751589 Mir5133 microRNA 5133 - - - - - 110257 587 56.18333333 80.69333333 0.522307265 Up 0.697055173 Hba-a2 "hemoglobin alpha, adult chain 2" K13822|1|3e-77|289|mmu:110257|hemoglobin subunit alpha GO:0043234//protein complex;GO:0015935//small ribosomal subunit GO:0046906//tetrapyrrole binding;GO:0022892//substrate-specific transporter activity;GO:0046914//transition metal ion binding;GO:0036094//small molecule binding GO:0015669;GO:0051259//protein oligomerization;GO:0000302//response to reactive oxygen species;GO:0008219//cell death;GO:0043009//chordate embryonic development;GO:0008217//regulation of blood pressure;GO:0019233//sensory perception of pain;GO:0030218//erythrocyte differentiation;GO:0042743//hydrogen peroxide metabolic process "gi|145301549|ref|NP_001077424.1|/2.50992e-76/hemoglobin alpha, adult chain 2 [Mus musculus]" 11475 2572 116.4733333 165.16 0.503864637 Up 0.696415811 Acta2 "actin, alpha 2, smooth muscle, aorta" "K12313|1|0.0|815|cge:100758575|actin, aortic smooth muscle" GO:0032991//macromolecular complex;GO:0043292//contractile fiber;GO:0032432//actin filament bundle GO:0032550;GO:0005198//structural molecule activity GO:0051707//response to other organism;GO:0007015//actin filament organization;GO:0007519//skeletal muscle tissue development;GO:0006939//smooth muscle contraction;GO:0072008;GO:0008015//blood circulation "gi|625206860|ref|XP_003505997.2|/0/PREDICTED: actin, aortic smooth muscle isoform X1 [Cricetulus griseus]" 12778 2070.24 33.86333333 22.77666667 -0.572167366 Down 0.695522585 Ackr3 atypical chemokine receptor 3 K04304|1|0.0|742|mmu:12778|C-X-C chemokine receptor type 7 GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0031224//intrinsic component of membrane;GO:0005768//endosome GO:0004950//chemokine receptor activity;GO:0004950//chemokine receptor activity GO:0022610;GO:0006915//apoptotic process;GO:0019221//cytokine-mediated signaling pathway;GO:0032502//developmental process;GO:0022610;GO:0006915//apoptotic process;GO:0019221//cytokine-mediated signaling pathway;GO:0032502//developmental process gi|31560715|ref|NP_031748.2|/0/atypical chemokine receptor 3 [Mus musculus] 230718 1103 3.746666667 1.343333333 -1.479790292 Down 0.694619956 Nt5c1a "5'-nucleotidase, cytosolic IA" K01081|1|0.0|682|mmu:230718|5'-nucleotidase [EC:3.1.3.5] GO:0044444//cytoplasmic part GO:0046872//metal ion binding;GO:0008252//nucleotidase activity;GO:0036094//small molecule binding GO:0009125;GO:0046128;GO:0006213//pyrimidine nucleoside metabolic process;GO:0009112;GO:0006163//purine nucleotide metabolic process gi|148227160|ref|NP_001078971.1|/0/cytosolic 5'-nucleotidase 1A [Mus musculus] 21955 1027.72 19.18333333 28.66666667 0.579520731 Up 0.694591748 Tnnt1 "troponin T1, skeletal, slow" "K10372|1|2e-72|274|cge:103163476|troponin T, slow skeletal muscle" GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0014721;GO:0014721;GO:0014721 "gi|149016651|gb|EDL75837.1|/2.05351e-71/troponin T1, skeletal, slow, isoform CRA_c [Rattus norvegicus]" 104367 118 7.02 3.58 -0.971511443 Down 0.694337884 Snora65 "small nucleolar RNA, H/ACA box 65" - - - - - 14955 2288 4.65 8.486666667 0.867967297 Up 0.693388243 H19 "H19, imprinted maternally expressed transcript" - - - - - 735264 98 0.97 3.13 1.690106005 Up 0.693077965 Mir671 microRNA 671 - - - - - 751543 109 0.01 1.223333333 6.934673752 Up 0.692955734 Mir690 microRNA 690 - - - - - 100316735 75 0.01 1.22 6.930737338 Up 0.692955734 Mir432 microRNA 432 - - - - - 100302730 9833 1.59 4.063333333 1.353636955 Up 0.692438602 5830417I10Rik gon-4-like pseudogene K15196|1|1e-27|129|mze:101481634|transcription factor IIIB 90 kDa subunit;K08451|2|2e-10|72.8|aqu:100635280|G protein-coupled receptor 64 - - - - 226123 1817 2.476666667 0.556666667 -2.153514108 Down 0.691272707 Morn4 MORN repeat containing 4 K19755|1|7e-14|81.6|bmor:101740871|radial spoke head protein 1 - - - gi|344243188|gb|EGV99291.1|/2.63286e-85/MORN repeat-containing protein 4 [Cricetulus griseus] 667410 2065 9.9 5.68 -0.801537595 Down 0.690717966 Gm8615 glucosamine-6-phosphate deaminase 1 pseudogene K02564|1|3e-142|508|mmu:26384|glucosamine-6-phosphate deaminase [EC:3.5.99.6] GO:0044424 "GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses" GO:0044237//cellular metabolic process;GO:0006041//glucosamine metabolic process;GO:0007338//single fertilization;GO:0044238//primary metabolic process gi|188219582|ref|NP_036067.2|/2.23437e-141/glucosamine-6-phosphate isomerase 1 [Mus musculus] 15331 1254 68.28333333 96.81 0.503622592 Up 0.690088006 Hmgn2 high mobility group nucleosomal binding domain 2 K11300|1|5e-23|111|mcf:102119260|high-mobility group nucleosome-binding domain-containing protein 2 GO:0043231//intracellular membrane-bounded organelle - GO:0050793//regulation of developmental process;GO:0006366//transcription from RNA polymerase II promoter gi|966979996|ref|XP_014967277.1|/7.61459e-37/PREDICTED: uncharacterized protein LOC100430578 isoform X2 [Macaca mulatta] 217166 2782 64.84 91.55666667 0.497780848 Up 0.68899733 Nr1d1 "nuclear receptor subfamily 1, group D, member 1" K03728|1|0.0|1054|mmu:217166|nuclear receptor subfamily 1 group D member 1 - - - - 78408 2271 17.80666667 11.45666667 -0.636230124 Down 0.688856294 Fam131a "family with sequence similarity 131, member A" K03260|1|2e-62|243|shr:100933156|translation initiation factor 4G - - - gi|29789331|ref|NP_598539.1|/2.83801e-177/protein FAM131A precursor [Mus musculus] 11504 4902 9.656666667 5.543333333 -0.800771516 Down 0.688245139 Adamts1 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1" K08617|1|0.0|1985|mmu:11504|a disintegrin and metalloproteinase with thrombospondin motifs 1 [EC:3.4.24.-] - - - - 100499518 77 1.193333333 0.01 -6.898853277 Down 0.688113506 Mir3470a microRNA 3470a - - - - - 118449 7116 33.80333333 23.10333333 -0.549064499 Down 0.687126255 Synpo2 synaptopodin 2 K18625|1|4e-10|71.2|ocu:100355160|protein Shroom - - - gi|226958463|ref|NP_536699.2|/0/synaptopodin-2 [Mus musculus] 69550 866 28.47666667 41.19333333 0.532630591 Up 0.686364662 Bst2 bone marrow stromal cell antigen 2 K06731|1|5e-65|249|mmu:69550|bone marrow stromal cell antigen 2 GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0044444//cytoplasmic part GO:0060089;GO:0042802//identical protein binding;GO:0004866//endopeptidase inhibitor activity GO:0051707//response to other organism;GO:0019079//viral genome replication;GO:0006955//immune response;GO:0030036//actin cytoskeleton organization;GO:0034097//response to cytokine;GO:0002252;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0016049//cell growth;GO:0006952//defense response;GO:0043901;GO:0016477//cell migration "gi|148696985|gb|EDL28932.1|/2.52405e-66/bone marrow stromal cell antigen 2, isoform CRA_b, partial [Mus musculus]" 69678 318 54.82666667 38.42666667 -0.512769929 Down 0.685057731 Atcayos "ataxia, cerebellar, Cayman type, opposite strand" - - - - - 66905 2159 149.8433333 107.6 -0.477776821 Down 0.68489789 Plin3 perilipin 3 K20287|1|0.0|806|mmu:66905|perilipin-3 GO:0044444//cytoplasmic part;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0006810//transport gi|13385312|ref|NP_080112.1|/0/perilipin-3 [Mus musculus] 11647 2524 53.73333333 37.70666667 -0.510997719 Down 0.684597014 Alpl "alkaline phosphatase, liver/bone/kidney" K01077|1|0.0|1022|mmu:11647|alkaline phosphatase [EC:3.1.3.1] - - - - 12609 2260 15.69 23.38666667 0.575840895 Up 0.684155102 Cebpd "CCAAT/enhancer binding protein (C/EBP), delta" "K10050|1|3e-122|441|mmu:12609|CCAAT/enhancer binding protein (C/EBP), delta" - - - - 17313 614 172.2433333 239.15 0.473467647 Up 0.683600361 Mgp matrix Gla protein K19481|1|5e-46|186|mmu:17313|matrix Gla protein GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044421 GO:0046872//metal ion binding;GO:0005515//protein binding GO:0030323//respiratory tube development;GO:0048869//cellular developmental process;GO:0001501//skeletal system development;GO:0060562//epithelial tube morphogenesis;GO:0030278//regulation of ossification;GO:0065003 gi|6678876|ref|NP_032623.1|/3.37609e-45/matrix Gla protein precursor [Mus musculus] 14695 1887 6.686666667 3.473333333 -0.944966328 Down 0.683092632 Gnb3 "guanine nucleotide binding protein (G protein), beta 3" K07825|1|0.0|701|hgl:101718903|guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0042995//cell projection GO:0060089;GO:0019899//enzyme binding GO:0009154//purine ribonucleotide catabolic process;GO:0007166//cell surface receptor signaling pathway gi|958784974|ref|XP_014722023.1|/0/PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1 [Equus asinus] 76980 2711 4.22 7.7 0.867615447 Up 0.682641318 Ube2ql1 ubiquitin-conjugating enzyme E2Q family-like 1 K10582|1|2e-107|393|rno:679949|ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23] - GO:0032550;GO:0019787//ubiquitin-like protein transferase activity - gi|223555981|ref|NP_001138634.1|/1.44765e-106/ubiquitin-conjugating enzyme E2Q-like protein 1 [Mus musculus] 387224 88 3.99 1.63 -1.291516782 Down 0.682528489 Mir29c microRNA 29c - - - - - 276952 3481 43.96 62.25333333 0.501959702 Up 0.682349844 Rasl10b "RAS-like, family 10, member B" K07851|1|4e-141|505|ptr:454588|Ras-like protein family member 10B GO:0016020//membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0001990//regulation of systemic arterial blood pressure by hormone;GO:0009154//purine ribonucleotide catabolic process;GO:0002793//positive regulation of peptide secretion;GO:0035556//intracellular signal transduction gi|694967496|ref|XP_009430660.1|/3.48213e-140/PREDICTED: ras-like protein family member 10B isoform X2 [Pan troglodytes] 67760 4645 39.49 27.54 -0.519958808 Down 0.680224905 Slc38a2 "solute carrier family 38, member 2" "K14207|1|0.0|790|mmu:67760|solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 2" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0046943//carboxylic acid transmembrane transporter activity GO:0046942//carboxylic acid transport;GO:0030001//metal ion transport gi|37360348|dbj|BAC98152.1|/0/mKIAA1382 protein [Mus musculus] 22437 5839 96.68 69.21333333 -0.482167486 Down 0.679576141 Xirp1 xin actin-binding repeat containing 1 K11588|1|5e-07|60.8|mze:101476582|methyl CpG binding protein 2;K03006|2|2e-06|58.9|cmk:103185088|DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K02085|3|2e-06|58.9|cjc:100385653|adenomatosis polyposis coli protein GO:0005913//cell-cell adherens junction;GO:0044291//cell-cell contact zone GO:0008092//cytoskeletal protein binding GO:0030239//myofibril assembly;GO:0006873//cellular ion homeostasis;GO:0008283//cell proliferation gi|285002266|ref|NP_035854.3|/0/xin actin-binding repeat-containing protein 1 [Mus musculus] 18208 5757 27.28333333 18.57333333 -0.554787159 Down 0.678090564 Ntn1 netrin 1 K06843|1|0.0|1201|mmu:18208|netrin 1 GO:0044424;GO:0005578//proteinaceous extracellular matrix GO:0005488//binding GO:0007411//axon guidance;GO:0030307//positive regulation of cell growth;GO:0060443//mammary gland morphogenesis;GO:0007155//cell adhesion;GO:0012501//programmed cell death;GO:0051647//nucleus localization;GO:0008283//cell proliferation;GO:0030308//negative regulation of cell growth;GO:0042471//ear morphogenesis;GO:0016477//cell migration gi|112363094|ref|NP_032770.2|/0/netrin-1 precursor [Mus musculus] 110557 981 6.523333333 10.8 0.727350057 Up 0.677874309 H2-Q6 "histocompatibility 2, Q region locus 6" "K06751|1|0.0|656|mmu:110557|major histocompatibility complex, class I" GO:0031224//intrinsic component of membrane;GO:0042611;GO:0009986//cell surface GO:0005515//protein binding;GO:0003823//antigen binding GO:0002484;GO:0001819//positive regulation of cytokine production;GO:0002664//regulation of T cell tolerance induction;GO:0002252;GO:0009581;GO:0002428 "gi|46559400|ref|NP_997531.1|/0/histocompatibility 2, Q region locus 6 precursor [Mus musculus]" 72386 1848 0.06 1.29 4.426264755 Up 0.677498214 2610035D17Rik RIKEN cDNA 2610035D17 gene - - - - - 70080 1895 1.53 3.793333333 1.309934499 Up 0.677084509 Igsf23 "immunoglobulin superfamily, member 23" K06499|1|9e-20|101|shr:100915860|carcinoembryonic antigen-related cell adhesion molecule - - - "gi|148691258|gb|EDL23205.1|/1.74635e-145/mCG54481, isoform CRA_b, partial [Mus musculus]" 66456 917 3.69 6.89 0.900883167 Up 0.676858851 2810001G20Rik RIKEN cDNA 2810001G20 gene - - - - gi|148678446|gb|EDL10393.1|/4.51586e-16/mCG147346 [Mus musculus] 18784 1982 22.16333333 31.96 0.528092531 Up 0.676426342 Pla2g5 "phospholipase A2, group V" K01047|1|1e-70|270|mmu:18784|secretory phospholipase A2 [EC:3.1.1.4] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0004623//phospholipase A2 activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0004623//phospholipase A2 activity GO:0046683//response to organophosphorus;GO:0046165;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0006796//phosphate-containing compound metabolic process;GO:0015909//long-chain fatty acid transport;GO:0046683//response to organophosphorus;GO:0046165;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0006796//phosphate-containing compound metabolic process;GO:0015909//long-chain fatty acid transport gi|26354847|dbj|BAC41050.1|/4.98379e-88/unnamed protein product [Mus musculus] 433406 2790 9.186666667 5.396666667 -0.767472902 Down 0.674827936 Gm13363 predicted gene 13363 K18041|1|2e-97|359|mcf:102134176|protein tyrosine phosphatase type IVA [EC:3.1.3.48] GO:0015630//microtubule cytoskeleton;GO:0044459;GO:0005768//endosome GO:0004725//protein tyrosine phosphatase activity GO:0016477//cell migration;GO:0006470//protein dephosphorylation;GO:0032502//developmental process "gi|148682476|gb|EDL14423.1|/1.07587e-96/protein tyrosine phosphatase 4a1, isoform CRA_b, partial [Mus musculus]" 20304 579 2.473333333 5.08 1.038371811 Up 0.674780924 Ccl5 chemokine (C-C motif) ligand 5 K12499|1|4e-33|142|rno:81780|C-C motif chemokine 5 GO:0044421;GO:0044424 GO:0030296//protein tyrosine kinase activator activity;GO:0048020//CCR chemokine receptor binding;GO:0016301//kinase activity;GO:0060229//lipase activator activity;GO:0042802//identical protein binding;GO:0048019//receptor antagonist activity;GO:0004629//phospholipase C activity;GO:0005539//glycosaminoglycan binding;GO:0005125//cytokine activity GO:0035685;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0002551//mast cell chemotaxis;GO:0070229//negative regulation of lymphocyte apoptotic process;GO:0034341//response to interferon-gamma;GO:0019079//viral genome replication;GO:0006875//cellular metal ion homeostasis;GO:0070555//response to interleukin-1;GO:0055099//response to high density lipoprotein particle;GO:0071363//cellular response to growth factor stimulus;GO:0051259//protein oligomerization;GO:0022409//positive regulation of cell-cell adhesion;GO:0001525//angiogenesis;GO:0043434//response to peptide hormone;GO:0006650//glycerophospholipid metabolic process;GO:0045860//positive regulation of protein kinase activity;GO:0008284//positive regulation of cell proliferation;GO:0036314;GO:0006970//response to osmotic stress;GO:0030182//neuron differentiation;GO:0002274;GO:0042098//T cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0031960//response to corticosteroid;GO:0010518//positive regulation of phospholipase activity;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0010467//gene expression;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0009891;GO:0010469//regulation of receptor activity;GO:0032722//positive regulation of chemokine production;GO:0032897//negative regulation of viral transcription;GO:0045471//response to ethanol;GO:0009967//positive regulation of signal transduction;GO:0034612//response to tumor necrosis factor;GO:0016192//vesicle-mediated transport;GO:0007186//G-protein coupled receptor signaling pathway;GO:0000096//sulfur amino acid metabolic process;GO:0050691//regulation of defense response to virus by host;GO:0033195;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0070230//positive regulation of lymphocyte apoptotic process;GO:0032571//response to vitamin K;GO:0001660//fever generation;GO:0014909//smooth muscle cell migration;GO:0006816//calcium ion transport;GO:0030031//cell projection assembly;GO:0043278//response to morphine "gi|537140398|gb|ERE67502.1|/8.73502e-34/c-C motif chemokine 5-like protein, partial [Cricetulus griseus]" 13076 2637 0.95 2.9 1.610053482 Up 0.674489451 Cyp1a1 "cytochrome P450, family 1, subfamily a, polypeptide 1" "K07408|1|0.0|1067|mmu:13076|cytochrome P450, family 1, subfamily A, polypeptide 1 [EC:1.14.14.1]" GO:0031090//organelle membrane;GO:0005740//mitochondrial envelope;GO:0031090//organelle membrane;GO:0005740//mitochondrial envelope "GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0033695;GO:0046906//tetrapyrrole binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0033695;GO:0046906//tetrapyrrole binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen" GO:0018894//dibenzo-p-dioxin metabolic process;GO:0015980//energy derivation by oxidation of organic compounds;GO:0008202//steroid metabolic process;GO:0010467//gene expression;GO:0042743//hydrogen peroxide metabolic process;GO:0009636//response to toxic substance;GO:0010039//response to iron ion;GO:0009698//phenylpropanoid metabolic process;GO:0017144//drug metabolic process;GO:0002138//retinoic acid biosynthetic process;GO:0001654//eye development;GO:0033013//tetrapyrrole metabolic process;GO:0000084//mitotic S phase;GO:0033273//response to vitamin;GO:0009790//embryo development;GO:0006805//xenobiotic metabolic process;GO:0030323//respiratory tube development;GO:0042493//response to drug;GO:0009404//toxin metabolic process;GO:0046686//response to cadmium ion;GO:0006950//response to stress;GO:0001889//liver development;GO:0007567//parturition;GO:0002237//response to molecule of bacterial origin;GO:0018894//dibenzo-p-dioxin metabolic process;GO:0015980//energy derivation by oxidation of organic compounds;GO:0008202//steroid metabolic process;GO:0010467//gene expression;GO:0042743//hydrogen peroxide metabolic process;GO:0009636//response to toxic substance;GO:0010039//response to iron ion;GO:0009698//phenylpropanoid metabolic process;GO:0017144//drug metabolic process;GO:0002138//retinoic acid biosynthetic process;GO:0001654//eye development;GO:0033013//tetrapyrrole metabolic process;GO:0000084//mitotic S phase;GO:0033273//response to vitamin;GO:0009790//embryo development;GO:0006805//xenobiotic metabolic process;GO:0030323//respiratory tube development;GO:0042493//response to drug;GO:0009404//toxin metabolic process;GO:0046686//response to cadmium ion;GO:0006950//response to stress;GO:0001889//liver development;GO:0007567//parturition;GO:0002237//response to molecule of bacterial origin gi|6753564|ref|NP_034122.1|/0/cytochrome P450 1A1 [Mus musculus] 723892 80 0.01 1.106666667 6.790076931 Up 0.674395427 Mir100 microRNA 100 - - - - - 80906 2385.49 106.73 147.2033333 0.46384459 Up 0.674047538 Kcnip2 Kv channel-interacting protein 2 K16575|1|6e-79|298|aam:106493806|centractin;K19932|2|1e-45|187|nve:NEMVE_v1g239489|neuronal calcium sensor 1 GO:0043005//neuron projection;GO:0044424;GO:0005887//integral component of plasma membrane;GO:0043005//neuron projection;GO:0044424;GO:0005887//integral component of plasma membrane;GO:0043005//neuron projection;GO:0044424;GO:0005887//integral component of plasma membrane;GO:0043005//neuron projection;GO:0044424;GO:0005887//integral component of plasma membrane GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0016247//channel regulator activity;GO:0015271//outward rectifier potassium channel activity;GO:0005048//signal sequence binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0016247//channel regulator activity;GO:0015271//outward rectifier potassium channel activity;GO:0005048//signal sequence binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0016247//channel regulator activity;GO:0015271//outward rectifier potassium channel activity;GO:0005048//signal sequence binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0016247//channel regulator activity;GO:0015271//outward rectifier potassium channel activity;GO:0005048//signal sequence binding GO:0003012//muscle system process;GO:0007267//cell-cell signaling;GO:0030001//metal ion transport;GO:0044057;GO:0051259//protein oligomerization;GO:0034220//ion transmembrane transport;GO:0045161//neuronal ion channel clustering;GO:0009593//detection of chemical stimulus;GO:0003012//muscle system process;GO:0007267//cell-cell signaling;GO:0030001//metal ion transport;GO:0044057;GO:0051259//protein oligomerization;GO:0034220//ion transmembrane transport;GO:0045161//neuronal ion channel clustering;GO:0009593//detection of chemical stimulus;GO:0003012//muscle system process;GO:0007267//cell-cell signaling;GO:0030001//metal ion transport;GO:0044057;GO:0051259//protein oligomerization;GO:0034220//ion transmembrane transport;GO:0045161//neuronal ion channel clustering;GO:0009593//detection of chemical stimulus;GO:0003012//muscle system process;GO:0007267//cell-cell signaling;GO:0030001//metal ion transport;GO:0044057;GO:0051259//protein oligomerization;GO:0034220//ion transmembrane transport;GO:0045161//neuronal ion channel clustering;GO:0009593//detection of chemical stimulus gi|444909156|ref|NP_001263287.1|/2.34048e-127/Kv channel-interacting protein 2 isoform d [Mus musculus] 193280 1056 5.66 9.496666667 0.746619163 Up 0.672420926 C030037D09Rik RIKEN cDNA C030037D09 gene - - - - - 100316684 83 1.093333333 0.01 -6.772589504 Down 0.671113995 Mir1898 microRNA 1898 - - - - - 213649 3397 10.69 6.556666667 -0.705227396 Down 0.670972959 Arhgef19 Rho guanine nucleotide exchange factor (GEF) 19 K07525|1|9e-95|351|lcm:102364542|neuronal guanine nucleotide exchange factor GO:0044464 GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity;GO:0008289//lipid binding GO:0009611//response to wounding;GO:0030036//actin cytoskeleton organization "gi|148681411|gb|EDL13358.1|/0/Rho guanine nucleotide exchange factor (GEF) 19, isoform CRA_b, partial [Mus musculus]" 96875 4179.57 6.273333333 3.306666667 -0.923854602 Down 0.670747302 Prg4 "proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)" K06251|1|1e-32|145|ocu:100009128|vitronectin - - - gi|148707530|gb|EDL39477.1|/0/mCG126040 [Mus musculus] 100039060 4539 0.89 2.773333333 1.639743786 Up 0.669863477 0610010B08Rik RIKEN cDNA 0610010B08 gene K09228|1|0.0|1094|mmu:100043915|KRAB domain-containing zinc finger protein - - - "gi|150246529|ref|NP_001092819.1|/0/KRAB box and zinc finger, C2H2 type domain containing [Mus musculus]" 21788 2505.06 23.27666667 15.90333333 -0.549555286 Down 0.669656625 Tfpi tissue factor pathway inhibitor K03909|1|5e-171|603|mmu:21788|tissue factor pathway inhibitor GO:0044421;GO:0044421;GO:0044421;GO:0016020//membrane GO:0004857//enzyme inhibitor activity;GO:0004857//enzyme inhibitor activity;GO:0030414//peptidase inhibitor activity;GO:0061135 GO:0007599//hemostasis;GO:0051346//negative regulation of hydrolase activity;GO:0007599//hemostasis;GO:0051346//negative regulation of hydrolase activity;GO:0007599//hemostasis;GO:0010466//negative regulation of peptidase activity;GO:0072376//protein activation cascade "gi|148695336|gb|EDL27283.1|/1.08975e-142/tissue factor pathway inhibitor, isoform CRA_c, partial [Mus musculus]" 100628582 81 0.01 1.08 6.754887502 Up 0.669289932 Mir3473c microRNA 3473c - - - - - 751551 110 6.493333333 10.57333333 0.703399094 Up 0.667682124 Mir680-2 microRNA 680-2 - - - - "gi|148706751|gb|EDL38698.1|/4.45922e-11/mCG1039710, partial [Mus musculus]" 100316811 84 1.07 0.01 -6.741466986 Down 0.66742826 Mir1930 microRNA 1930 - - - - - 17025 4534.17 13.76333333 20.33666667 0.563253312 Up 0.666704276 Alad "aminolevulinate, delta-, dehydratase" K01698|1|0.0|637|mmu:17025|porphobilinogen synthase [EC:4.2.1.24] GO:0044444//cytoplasmic part;GO:0044421;GO:0044444//cytoplasmic part;GO:0044421 GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0016836//hydro-lyase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0016836//hydro-lyase activity GO:0009314//response to radiation;GO:0001101//response to acid chemical;GO:0097305//response to alcohol;GO:0051259//protein oligomerization;GO:0010243//response to organonitrogen compound;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0007584//response to nutrient;GO:0031960//response to corticosteroid;GO:0002237//response to molecule of bacterial origin;GO:0070670//response to interleukin-4;GO:0010288//response to lead ion;GO:0006950//response to stress;GO:0009314//response to radiation;GO:0001101//response to acid chemical;GO:0097305//response to alcohol;GO:0051259//protein oligomerization;GO:0010243//response to organonitrogen compound;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0007584//response to nutrient;GO:0031960//response to corticosteroid;GO:0002237//response to molecule of bacterial origin;GO:0070670//response to interleukin-4;GO:0010288//response to lead ion;GO:0006950//response to stress gi|34328485|ref|NP_032551.3|/7.86413e-180/delta-aminolevulinic acid dehydratase [Mus musculus] 78688 2869 31.14 21.92333333 -0.506301775 Down 0.666046109 Nol3 nucleolar protein 3 (apoptosis repressor with CARD domain) K09417|1|1e-65|254|tup:102480034|heat shock transcription factor 4;K12797|4|3e-11|73.6|myb:102249258|caspase recruitment domain-containing protein 6 - - - - 14131 1353 12.89 19.10333333 0.567572132 Up 0.665641807 Fcgr3 "Fc receptor, IgG, low affinity III" K16824|1|9e-151|535|mmu:14131|low affinity immunoglobulin gamma Fc region receptor II-c;K06472|2|3e-111|404|rno:498276|low affinity immunoglobulin gamma Fc region receptor II-a;K06463|5|4e-107|390|rno:116591|low affinity immunoglobulin gamma Fc region receptor III GO:0031224//intrinsic component of membrane GO:0019763//immunoglobulin receptor activity;GO:0019865//immunoglobulin binding GO:0001802;GO:0006909//phagocytosis;GO:0006837//serotonin transport;GO:0002274;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0038093//Fc receptor signaling pathway;GO:0001794;GO:0007399//nervous system development;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0001810;GO:0030595//leukocyte chemotaxis gi|190570188|ref|NP_034318.2|/7.47596e-150/low affinity immunoglobulin gamma Fc region receptor III precursor [Mus musculus] 100316821 82 1.06 0.01 -6.727920455 Down 0.6656136 Mir1981 microRNA 1981 - - - - - 27208 82 1.06 0.01 -6.727920455 Down 0.6656136 Snord33 "small nucleolar RNA, C/D box 33" - - - - - 13010 813 538.2433333 723.2033333 0.426142782 Up 0.665199895 Cst3 cystatin C K13899|1|6e-65|249|mmu:13010|cystatin-C - - - - 81013 2685 0.88 2.706666667 1.620941798 Up 0.665002445 Vmn1r65 vomeronasal 1 receptor 65 K04614|1|0.0|676|mmu:81013|vomeronasal1 receptor GO:0031224//intrinsic component of membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway "gi|13507700|ref|NP_109663.1|/0/vomeronasal 1 receptor, D6 [Mus musculus]" 18639 1753 9.153333333 14.05666667 0.618885396 Up 0.664287863 Pfkfb1 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1" "K19028|1|0.0|927|cge:100754096|6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 1 [EC:2.7.1.105 3.1.3.46]" GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0032550;GO:0043168//anion binding;GO:0008443//phosphofructokinase activity;GO:0050308//sugar-phosphatase activity;GO:0019899//enzyme binding GO:0033131;GO:0046683//response to organophosphorus;GO:0009887//organ morphogenesis;GO:0043434//response to peptide hormone;GO:0031960//response to corticosteroid;GO:0006950//response to stress "gi|402692079|ref|NP_001257992.1|/0/6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 2 [Rattus norvegicus]" 100124459 85 1.05 0.01 -6.714245518 Down 0.66376133 Mir877 microRNA 877 - - - - - 11522 1348 64.27666667 46.61 -0.463655601 Down 0.661796232 Adh1 alcohol dehydrogenase 1 (class I) K13951|1|0.0|728|mmu:11522|alcohol dehydrogenase 1/7 [EC:1.1.1.1] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0043168//anion binding;GO:0046914//transition metal ion binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0000166//nucleotide binding" GO:0048545//response to steroid hormone;GO:0001523//retinoid metabolic process;GO:0006117//acetaldehyde metabolic process;GO:0006067//ethanol metabolic process;GO:0009887//organ morphogenesis;GO:0030534//adult behavior gi|6724311|ref|NP_031435.1|/0/alcohol dehydrogenase 1 [Mus musculus] 104368 129 0.01 1.04 6.700439718 Up 0.661768024 Snora70 "small nucleolar RNA, H/ACA box 70" - - - - - 16391 2435.46 12.08333333 17.96333333 0.572036592 Up 0.661758622 Irf9 interferon regulatory factor 9 K04693|1|0.0|746|mmu:16391|interferon regulatory factor 9 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0001067;GO:0001071//nucleic acid binding transcription factor activity;GO:0001067;GO:0001071//nucleic acid binding transcription factor activity;GO:0001067 "GO:0032606//type I interferon production;GO:0006351//transcription, DNA-templated;GO:0032606//type I interferon production;GO:0006351//transcription, DNA-templated;GO:0032606//type I interferon production;GO:0006351//transcription, DNA-templated" gi|226874925|ref|NP_001152889.1|/0/interferon regulatory factor 9 isoform 1 [Mus musculus] 320795 3410.12 32.26 22.88333333 -0.495449219 Down 0.661702208 Pkn1 protein kinase N1 K06071|1|0.0|1532|mmu:320795|protein kinase N [EC:2.7.11.13] GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0032155;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0032155 GO:0032550;GO:0019901//protein kinase binding;GO:0035184//histone threonine kinase activity;GO:0003713//transcription coactivator activity;GO:0035258//steroid hormone receptor binding;GO:0017048//Rho GTPase binding;GO:0032550;GO:0019901//protein kinase binding;GO:0035184//histone threonine kinase activity;GO:0003713//transcription coactivator activity;GO:0035258//steroid hormone receptor binding;GO:0017048//Rho GTPase binding GO:0006366//transcription from RNA polymerase II promoter;GO:0001667//ameboidal-type cell migration;GO:0007154//cell communication;GO:0006970//response to osmotic stress;GO:0035405;GO:0040012//regulation of locomotion;GO:0006366//transcription from RNA polymerase II promoter;GO:0001667//ameboidal-type cell migration;GO:0007154//cell communication;GO:0006970//response to osmotic stress;GO:0035405;GO:0040012//regulation of locomotion gi|313760674|ref|NP_001186522.1|/0/serine/threonine-protein kinase N1 isoform 1 [Mus musculus] 14778 1517 193.5166667 259.9966667 0.426035303 Up 0.661025236 Gpx3 glutathione peroxidase 3 K00432|1|4e-121|437|mmu:14778|glutathione peroxidase [EC:1.11.1.9] - - - - 74374 6238 17.44333333 11.74 -0.57124335 Down 0.659614878 Clec16a "C-type lectin domain family 16, member A" K19513|1|0.0|1869|mmu:74374|protein CLEC16A - - - - 319476 7318 77.77666667 56.74 -0.454971255 Down 0.659567866 Lrtm1 leucine-rich repeats and transmembrane domains 1 K06839|1|7e-19|100|sko:102806385|slit 2;K06838|3|3e-18|98.2|tru:101061888|slit 1 GO:0031224//intrinsic component of membrane - - gi|28892715|ref|NP_795894.1|/4.08679e-173/leucine-rich repeat and transmembrane domain-containing protein 1 precursor [Mus musculus] 18104 1552 28.26666667 39.4 0.479093866 Up 0.659172966 Nqo1 "NAD(P)H dehydrogenase, quinone 1" K00355|1|2e-148|528|mmu:18104|NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] GO:0044297//cell body;GO:0044444//cytoplasmic part "GO:0005488//binding;GO:0016653//oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor;GO:0016209//antioxidant activity;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor" GO:0097305//response to alcohol;GO:0044092//negative regulation of molecular function;GO:0043627//response to estrogen;GO:0031667//response to nutrient levels;GO:0043065//positive regulation of apoptotic process;GO:0072593//reactive oxygen species metabolic process;GO:0006520//cellular amino acid metabolic process;GO:0044767//single-organism developmental process;GO:0044271//cellular nitrogen compound biosynthetic process;GO:0007268//chemical synaptic transmission;GO:0006950//response to stress gi|94400773|ref|NP_032732.3|/1.88082e-147/NAD(P)H dehydrogenase [quinone] 1 [Mus musculus] 751525 109 15.51333333 10.34333333 -0.584807514 Down 0.658270337 Mir686 microRNA 686 K02737|1|1e-13|76.6|dre:30387|20S proteasome subunit beta 5 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity GO:0006950//response to stress;GO:0006511//ubiquitin-dependent protein catabolic process "gi|169146058|emb|CAQ14651.1|/1.38619e-12/proteasome (prosome, macropain) subunit, beta type, 5 [Danio rerio]" 67895 1292 32.74 45.21333333 0.465693962 Up 0.658157509 Ppa1 pyrophosphatase (inorganic) 1 K01507|1|4e-174|613|mmu:67895|inorganic pyrophosphatase [EC:3.6.1.1] GO:0044424 GO:0016462//pyrophosphatase activity;GO:0043169//cation binding GO:0006793//phosphorus metabolic process "gi|148700191|gb|EDL32138.1|/0/pyrophosphatase (inorganic) 1, partial [Mus musculus]" 69564 1840 4.89 8.226666667 0.750473523 Up 0.657837828 Nmrk2 nicotinamide riboside kinase 2 K10524|1|2e-111|405|mmu:69564|nicotinamide/nicotinate riboside kinase [EC:2.7.1.22 2.7.1.173] GO:0044464 GO:0043169//cation binding;GO:0032550;GO:0016301//kinase activity GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0045445//myoblast differentiation gi|110625739|ref|NP_081396.1|/1.76451e-110/nicotinamide riboside kinase 2 [Mus musculus] 104370 98 2.343333333 0.666666667 -1.813524689 Down 0.657555756 Snora68 "small nucleolar RNA, H/ACA box 68" - - - - "gi|148696943|gb|EDL28890.1|/1.59859e-08/mCG14783, isoform CRA_f [Mus musculus]" 100039192 1272.26 1.853333333 4.023333333 1.118268888 Up 0.657179661 Tmem254c transmembrane protein 254c - GO:0043231//intracellular membrane-bounded organelle - GO:0002761//regulation of myeloid leukocyte differentiation;GO:0044710 gi|292781931|ref|NP_080955.1|/4.48103e-63/transmembrane protein 254 isoform 1 [Mus musculus] 225638 7250 42.45666667 30.67 -0.469162941 Down 0.656286434 Alpk2 alpha-kinase 2 K08868|1|0.0|4208|mmu:225638|alpha-kinase - - - gi|254675181|ref|NP_001032371.1|/0/alpha-protein kinase 2 [Mus musculus] 104795949 77 0.01 1.01 6.658211483 Up 0.656145398 Gm38670 "predicted gene, 38670" - - - - - 100043489 825.48 2.886666667 5.473333333 0.923015197 Up 0.654161495 1300002E11Rik RIKEN cDNA 1300002E11 gene - - - - - 100040563 693 34.05 46.85666667 0.460599528 Up 0.654105081 Dynlt1c dynein light chain Tctex-type 1C K10420|1|9e-60|231|mmu:21648|dynein light chain Tctex-type 1 GO:0043231//intracellular membrane-bounded organelle;GO:0030286//dynein complex GO:0005515//protein binding;GO:0003774//motor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0031175//neuron projection development;GO:0006886//intracellular protein transport;GO:0040001//establishment of mitotic spindle localization;GO:0010721//negative regulation of cell development;GO:0019048//modulation by virus of host morphology or physiology;GO:0000087//mitotic M phase gi|6678265|ref|NP_033368.1|/7.19312e-59/dynein light chain Tctex-type 1 [Mus musculus] 214359 1874 1.916666667 4.073333333 1.087610424 Up 0.6537854 Tmem51 transmembrane protein 51 - GO:0031224//intrinsic component of membrane - - gi|21703804|ref|NP_663377.1|/7.33329e-112/transmembrane protein 51 [Mus musculus] 12700 3009.78 43.08666667 58.68666667 0.445791276 Up 0.653428109 Cish cytokine inducible SH2-containing protein K04701|1|2e-146|523|mmu:12700|cytokine inducible SH2-containing protein - - - - 100415914 757 8.853333333 5.413333333 -0.709703514 Down 0.652478469 Gm12505 predicted gene 12505 - - - - - 100216536 78 0.01 0.986666667 6.624490865 Up 0.652346835 Snord1c "small nucleolar RNA, C/D box 1C" - - - - - 66835 88 0.986666667 0.01 -6.624490865 Down 0.652346835 Snord123 "small nucleolar RNA, C/D box 123" - - - - - 66180 1903 14.83666667 21.28 0.520331151 Up 0.651162135 P3h4 prolyl 3-hydroxylase family member 4 (non-enzymatic) K19606|1|2e-105|385|fca:101097013|cartilage-associated protein GO:0000794//condensed nuclear chromosome - GO:0007129//synapsis gi|31543672|ref|NP_789800.1|/0/synaptonemal complex protein SC65 precursor [Mus musculus] 140492 3423.94 1.88 3.996666667 1.088064591 Up 0.650880063 Kcnn2 "potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2" K04943|1|0.0|907|mmu:140492|potassium intermediate/small conductance calcium-activated channel subfamily N member 2 GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0044297//cell body;GO:0031674//I band;GO:0042383//sarcolemma;GO:0005783//endoplasmic reticulum GO:0015269//calcium-activated potassium channel activity;GO:0042802//identical protein binding;GO:0042805//actinin binding;GO:0046983//protein dimerization activity GO:0034765//regulation of ion transmembrane transport;GO:0048167//regulation of synaptic plasticity;GO:0030001//metal ion transport gi|921274049|ref|NP_001299834.1|/0/small conductance calcium-activated potassium channel protein 2 isoform SK2-L [Mus musculus] 667780 1293 0.01 0.983333333 6.619608644 Up 0.650626199 Gm13871 predicted gene 13871 - - - - - 319477 2139 17.74333333 25.16 0.503854857 Up 0.65051337 6030419C18Rik RIKEN cDNA 6030419C18 gene - - - - "gi|148694006|gb|EDL25953.1|/2.48229e-143/RIKEN cDNA 6030419C18, partial [Mus musculus]" 67464 3084 68.89333333 92.63 0.427115131 Up 0.650334725 Entpd4 ectonucleoside triphosphate diphosphohydrolase 4 K12305|1|0.0|1169|mmu:67464|ectonucleoside triphosphate diphosphohydrolase 4 [EC:3.6.1.6] GO:0031228//intrinsic component of Golgi membrane GO:0017110//nucleoside-diphosphatase activity - gi|18093090|ref|NP_080450.1|/0/ectonucleoside triphosphate diphosphohydrolase 4 [Mus musculus] 320027 3117 1.74 3.796666667 1.125646035 Up 0.649996239 Fstl4 follistatin-like 4 K19511|1|4e-16|90.1|tca:656984|peroxidase [EC:1.11.1.7];K17341|3|1e-15|88.6|sko:102806401|hemicentin - GO:0043169//cation binding - "gi|148701660|gb|EDL33607.1|/0/follistatin-like 4, isoform CRA_b, partial [Mus musculus]" 22040 1069.92 15.73666667 22.42 0.510656296 Up 0.649826996 Trex1 three prime repair exonuclease 1 K10790|1|1e-133|478|mmu:22040|three prime repair exonuclease 1 [EC:3.1.11.2] - - - - 20266 1568 17.62666667 24.89333333 0.497999751 Up 0.649375682 Scn1b "sodium channel, voltage-gated, type I, beta" K04845|1|1e-91|339|mmu:20266|voltage-gated sodium channel type I beta GO:0044291//cell-cell contact zone;GO:0042383//sarcolemma;GO:0034703//cation channel complex;GO:0033267;GO:0005887//integral component of plasma membrane GO:0086006//voltage-gated sodium channel activity involved in cardiac muscle cell action potential;GO:0008200//ion channel inhibitor activity;GO:0005488//binding GO:0007411//axon guidance;GO:0002027//regulation of heart rate;GO:0006941//striated muscle contraction;GO:0007267//cell-cell signaling;GO:0010975//regulation of neuron projection development;GO:0017085//response to insecticide;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0060306//regulation of membrane repolarization;GO:0003254//regulation of membrane depolarization;GO:0022610;GO:0050877//neurological system process;GO:0002028//regulation of sodium ion transport "gi|148692003|gb|EDL23950.1|/3.88574e-108/sodium channel, voltage-gated, type I, beta, isoform CRA_a, partial [Mus musculus]" 66373 516 4.86 2.48 -0.970616193 Down 0.649319267 Lsm5 "LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated" K12624|1|3e-45|182|gja:107105738|U6 snRNA-associated Sm-like protein LSm5 - - - - 20425 2074 6.403333333 3.626666667 -0.820178962 Down 0.649234646 Shmt1 serine hydroxymethyltransferase 1 (soluble) K00600|1|0.0|939|mmu:20425|glycine hydroxymethyltransferase [EC:2.1.2.1] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0008238//exopeptidase activity;GO:0016742//hydroxymethyl-, formyl- and related transferase activity;GO:0042802//identical protein binding;GO:0031406//carboxylic acid binding;GO:0004793//threonine aldolase activity" GO:0006578//amino-acid betaine biosynthetic process;GO:0006144//purine nucleobase metabolic process;GO:0006766//vitamin metabolic process;GO:0051260//protein homooligomerization;GO:0006730//one-carbon metabolic process;GO:0006545//glycine biosynthetic process;GO:0006563//L-serine metabolic process;GO:0006760//folic acid-containing compound metabolic process "gi|67846103|ref|NP_033197.2|/0/serine hydroxymethyltransferase, cytosolic [Mus musculus]" 21356 2747.8 35.59666667 48.68 0.451587017 Up 0.649206439 Tapbp TAP binding protein K08058|1|0.0|749|mmu:21356|TAP binding protein (tapasin) GO:0042824//MHC class I peptide loading complex;GO:0042824//MHC class I peptide loading complex GO:0046977;GO:0046977 GO:0002396;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0006950//response to stress;GO:0002396;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0006950//response to stress "gi|148678278|gb|EDL10225.1|/0/TAP binding protein, isoform CRA_a, partial [Mus musculus]" 68695 860 13.91666667 9.323333333 -0.577895944 Down 0.649178232 Hddc3 HD domain containing 3 "K01139|1|4e-76|286|mmu:68695|guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2]" - GO:0016794;GO:0043169//cation binding - "gi|21312092|ref|NP_081088.1|/2.93447e-75/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 [Mus musculus]" 21828 3202 1.953333333 4.08 1.062630988 Up 0.648886758 Thbs4 thrombospondin 4 K04659|1|0.0|1796|mmu:21828|thrombospondin 2/3/4/5 GO:0005578//proteinaceous extracellular matrix;GO:0045202//synapse GO:0005102//receptor binding;GO:0043236//laminin binding;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding GO:0001934//positive regulation of protein phosphorylation;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0090136//epithelial cell-cell adhesion;GO:0031175//neuron projection development;GO:0051259//protein oligomerization;GO:0014812//muscle cell migration gi|6755781|ref|NP_035712.1|/0/thrombospondin-4 precursor [Mus musculus] 100217469 60 4.193333333 2.04 -1.039528364 Down 0.64846365 Snord91a "small nucleolar RNA, C/D box 91A" - - - - - 19242 2021 0.326666667 1.713333333 2.390914705 Up 0.648115762 Ptn pleiotrophin K16642|1|5e-70|226|ecb:100064880|pleiotrophin GO:0031012//extracellular matrix;GO:0043231//intracellular membrane-bounded organelle GO:0005539//glycosaminoglycan binding;GO:0005102//receptor binding GO:0048522;GO:0001503//ossification;GO:0007611//learning or memory "gi|953851560|ref|XP_014594832.1|/4.26946e-69/PREDICTED: pleiotrophin, partial [Equus caballus]" 75731 1467 8.783333333 13.20666667 0.588425918 Up 0.647720862 Idnk idnK gluconokinase homolog (E. coli) K00851|1|5e-92|340|mmu:75731|gluconokinase [EC:2.7.1.12] GO:0044424;GO:0044424 GO:0016301//kinase activity;GO:0032550;GO:0016301//kinase activity;GO:0032550 GO:0019521//D-gluconate metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0019521//D-gluconate metabolic process;GO:0006796//phosphate-containing compound metabolic process gi|114205442|ref|NP_932121.2|/2.00205e-76/probable gluconokinase isoform a [Mus musculus] 68255 1251 1.16 2.983333333 1.362800376 Up 0.647325962 Tmem86b transmembrane protein 86B K18575|1|6e-130|466|mmu:68255|alkenylglycerophosphocholine/alkenylglycerophosphoethanolamine hydrolase [EC:3.3.2.2 3.3.2.5] GO:0005737//cytoplasm;GO:0031224//intrinsic component of membrane GO:0016803 GO:0018904 "gi|148699300|gb|EDL31247.1|/8.14995e-148/transmembrane protein 86B, partial [Mus musculus]" 100316776 86 0.96 0.01 -6.584962501 Down 0.647015683 Mir1954 microRNA 1954 - - - - - 627914 4538 0.96 0.01 -6.584962501 Down 0.647015683 Gm14430 predicted gene 14430 K09228|1|0.0|1094|mmu:100043915|KRAB domain-containing zinc finger protein - - - "gi|150246529|ref|NP_001092819.1|/0/KRAB box and zinc finger, C2H2 type domain containing [Mus musculus]" 208266 5694 13.51666667 9.046666667 -0.579281194 Down 0.64688405 Dot1l "DOT1-like, histone H3 methyltransferase (S. cerevisiae)" "K11427|1|0.0|2615|mmu:208266|histone-lysine N-methyltransferase, H3 lysine-79 specific [EC:2.1.1.43]" - GO:0016279//protein-lysine N-methyltransferase activity GO:0016571//histone methylation;GO:0051101//regulation of DNA binding;GO:0007259//JAK-STAT cascade "gi|148699559|gb|EDL31506.1|/0/DOT1-like, histone H3 methyltransferase (S. cerevisiae), isoform CRA_c, partial [Mus musculus]" 20194 650 74.09333333 55.09 -0.427553277 Down 0.646517357 S100a10 S100 calcium binding protein A10 (calpactin) K17274|1|2e-50|200|mmu:20194|calpactin-1 light chain GO:0043231//intracellular membrane-bounded organelle;GO:0019898//extrinsic component of membrane - GO:0044093;GO:0001101//response to acid chemical gi|6677833|ref|NP_033138.1|/1.53165e-49/protein S100-A10 [Mus musculus] 20307 517 1.016666667 2.776666667 1.449507253 Up 0.646272895 Ccl8 chemokine (C-C motif) ligand 8 K16596|1|3e-50|199|mmu:20307|C-C motif chemokine 8 GO:0044421 GO:0060229//lipase activator activity;GO:0005125//cytokine activity;GO:0005539//glycosaminoglycan binding;GO:0016301//kinase activity GO:0016192//vesicle-mediated transport;GO:0006952//defense response;GO:0051707//response to other organism;GO:0006464//cellular protein modification process;GO:0006875//cellular metal ion homeostasis;GO:0002376//immune system process;GO:0042221//response to chemical;GO:0007154//cell communication;GO:0070838//divalent metal ion transport gi|10946818|ref|NP_067418.1|/1.7718e-49/C-C motif chemokine 8 precursor [Mus musculus] 214531 3245 2.886666667 1.1 -1.391901 Down 0.646000226 Tmprss13 "transmembrane protease, serine 13" K09643|1|0.0|880|mmu:214531|transmembrane protease serine 13 GO:0031224//intrinsic component of membrane GO:0038024//cargo receptor activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process "gi|27503083|gb|AAH42878.1|/0/Tmprss13 protein, partial [Mus musculus]" 100217417 118 2.973333333 1.163333333 -1.353816674 Down 0.645887397 Snora34 "small nucleolar RNA, H/ACA box 34" - - - - - 100463512 334 3089.72 2338.196667 -0.402079822 Down 0.64585919 Gm20594 "predicted gene, 20594" - - - - gi|299758462|ref|NP_001177661.1|/2.88622e-13/Mtrnr2-like [Mus musculus] 76282 1809 25.29333333 18.01666667 -0.489425061 Down 0.645370266 Gpt "glutamic pyruvic transaminase, soluble" K00814|1|0.0|975|mmu:76282|alanine transaminase [EC:2.6.1.2] - - - - 15018 1416.01 7.69 11.75333333 0.612014471 Up 0.645323254 H2-Q7 "histocompatibility 2, Q region locus 7" "K06751|1|7e-108|392|mmu:15018|major histocompatibility complex, class I" GO:0031224//intrinsic component of membrane;GO:0042611;GO:0009986//cell surface;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0042611;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0042611 GO:0005515//protein binding;GO:0003823//antigen binding;GO:0003823//antigen binding;GO:0003823//antigen binding GO:0002484;GO:0001819//positive regulation of cytokine production;GO:0002664//regulation of T cell tolerance induction;GO:0002252;GO:0009581;GO:0002428;GO:0002252;GO:0001819//positive regulation of cytokine production;GO:0002428;GO:0002252;GO:0001819//positive regulation of cytokine production;GO:0002428 gi|53872|emb|CAA28977.1|/2.93485e-177/unnamed protein product [Mus musculus] 74309 3640.15 12.53666667 18.13666667 0.532755522 Up 0.645257437 Osbp2 oxysterol binding protein 2 K20462|1|0.0|1090|mmu:74309|oxysterol-binding protein 2 - GO:0032934//sterol binding;GO:0032934//sterol binding GO:0051234//establishment of localization;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0010876//lipid localization gi|61744458|ref|NP_690031.2|/0/oxysterol-binding protein 2 isoform 1 [Mus musculus] 14230 2619 10.12333333 14.97333333 0.564711019 Up 0.645191621 Fkbp10 FK506 binding protein 10 K09575|1|0.0|1151|mmu:14230|FK506-binding protein 9/10 [EC:5.2.1.8] - - - gi|254939534|ref|NP_034351.2|/0/peptidyl-prolyl cis-trans isomerase FKBP10 isoform 1 precursor [Mus musculus] 387153 90 0.95 0.01 -6.569855608 Down 0.644956561 Mir135a-1 microRNA 135a-1 - - - - - 100217451 129 0.516666667 2.033333333 1.976541027 Up 0.644881342 Snora7a "small nucleolar RNA, H/ACA box 7A" K02912|1|2e-11|69.7|phd:102318579|large subunit ribosomal protein L32e - - - gi|556719835|ref|XP_005955798.1|/1.7448e-10/PREDICTED: 60S ribosomal protein L32 isoform X1 [Pantholops hodgsonii] 333182 521 4.066666667 1.973333333 -1.043212067 Down 0.644185565 Cox6b2 cytochrome c oxidase subunit VIb polypeptide 2 K02267|1|4e-36|132|mmu:333182|cytochrome c oxidase subunit 6b GO:0005743//mitochondrial inner membrane;GO:0005743//mitochondrial inner membrane;GO:0005743//mitochondrial inner membrane GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity GO:0044710;GO:0044710;GO:0044710 gi|577861048|ref|NP_001276778.1|/7.7868e-48/cytochrome c oxidase subunit 6B2 isoform 2 [Mus musculus] 77976 5032 8.666666667 5.366666667 -0.691450935 Down 0.644016323 Nuak1 "NUAK family, SNF1-like kinase, 1" "K08800|1|0.0|1160|mmu:77976|NUAK family, SNF1-like kinase [EC:2.7.11.1]" GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity;GO:0005515//protein binding GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0006464//cellular protein modification process;GO:0007155//cell adhesion;GO:0080135//regulation of cellular response to stress;GO:0008283//cell proliferation "gi|148689452|gb|EDL21399.1|/0/ZNUAK family, SNF1-like kinase, 1, partial [Mus musculus]" 105501 2470.69 30.30333333 41.32 0.447363757 Up 0.643818872 Abhd4 abhydrolase domain containing 4 K13698|1|0.0|739|mmu:105501|abhydrolase domain-containing protein 4 - GO:0003824//catalytic activity GO:0006629//lipid metabolic process gi|326937491|ref|NP_598837.2|/0/protein ABHD4 isoform 1 [Mus musculus] 14667 4257 8.34 12.55333333 0.58995121 Up 0.64337696 Gm2a GM2 ganglioside activator protein K12383|1|1e-93|348|mmu:14667|ganglioside GM2 activator GO:0044448;GO:0000323//lytic vacuole;GO:0031981//nuclear lumen;GO:0005887//integral component of plasma membrane GO:0004563//beta-N-acetylhexosaminidase activity;GO:0005488//binding;GO:0022892//substrate-specific transporter activity;GO:0060229//lipase activator activity GO:0050905//neuromuscular process;GO:0001573//ganglioside metabolic process;GO:0010876//lipid localization;GO:0044708//single-organism behavior;GO:0009311//oligosaccharide metabolic process;GO:0043085//positive regulation of catalytic activity gi|6806917|ref|NP_034429.1|/8.90737e-93/ganglioside GM2 activator precursor [Mus musculus] 208076 3528.99 4.193333333 7.096666667 0.759044028 Up 0.643254729 Pknox2 Pbx/knotted 1 homeobox 2 K16670|1|5e-60|236|pale:102886688|homeobox protein Meis2;K16672|4|1e-58|231|nvi:100117144|homeobox protein homothorax GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003779//actin binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003779//actin binding GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter gi|71067110|ref|NP_683752.2|/0/homeobox protein PKNOX2 [Mus musculus] 30794 1189 24.19333333 17.21 -0.491362459 Down 0.643113694 Pdlim4 PDZ and LIM domain 4 K19867|1|1e-23|113|tca:658986|LIM domain-binding protein 3 - GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding GO:0007010//cytoskeleton organization gi|251823786|ref|NP_062290.2|/0/PDZ and LIM domain protein 4 [Mus musculus] 20971 2460 7.97 12.06 0.597578278 Up 0.643085486 Sdc4 syndecan 4 K16338|1|1e-79|300|mmu:20971|syndecan 4 - - - - 100628611 88 0.01 0.936666667 6.549463819 Up 0.64278461 Mir5107 microRNA 5107 - - - - - 100302592 87 0.94 0.01 -6.554588852 Down 0.64278461 Snord14a "small nucleolar RNA, C/D box 14A" - - - - - 102466206 88 0.01 0.936666667 6.549463819 Up 0.64278461 Mir6903 microRNA 6903 - - - - - 22433 2264 24.31333333 33.48333333 0.461695459 Up 0.641938396 Xbp1 X-box binding protein 1 K09027|1|4e-149|348|ngi:103734968|X box-binding protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0042221//response to chemical;GO:0006984//ER-nucleus signaling pathway;GO:0031016//pancreas development;GO:0002070//epithelial cell maturation;GO:0009967//positive regulation of signal transduction;GO:0009628//response to abiotic stimulus;GO:0001820//serotonin secretion;GO:0006351//transcription, DNA-templated;GO:0031016//pancreas development;GO:0002070//epithelial cell maturation;GO:0009967//positive regulation of signal transduction;GO:0009628//response to abiotic stimulus;GO:0002376//immune system process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0001820//serotonin secretion" gi|411147451|ref|NP_001258659.1|/4.03315e-168/X-box-binding protein 1 isoform XBP1(S) [Mus musculus] 17929 5334.16 329.76 249.5866667 -0.401875545 Down 0.641816165 Myom1 myomesin 1 K12567|1|5e-64|249|sko:102801020|titin [EC:2.7.11.1] GO:0016459//myosin complex;GO:0031672//A band;GO:0016459//myosin complex;GO:0031672//A band - GO:0003012//muscle system process;GO:0003012//muscle system process gi|145279175|ref|NP_034997.2|/0/myomesin-1 isoform 1 [Mus musculus] 272381 2753 9.246666667 13.7 0.567170606 Up 0.64100756 Lrrc4b leucine rich repeat containing 4B K16360|1|0.0|1086|mmu:272381|netrin-G3 ligand GO:0016020//membrane;GO:0045202//synapse GO:0005515//protein binding GO:0007416//synapse assembly gi|38016190|ref|NP_937893.1|/0/leucine-rich repeat-containing protein 4B precursor [Mus musculus] 27212 87 0.01 0.93 6.539158811 Up 0.640847719 Snord35b "small nucleolar RNA, C/D box 35B" - - - - - 56219 4129 11.22 7.37 -0.606336152 Down 0.640349393 Extl1 exostoses (multiple)-like 1 "K02368|1|0.0|1326|mmu:56219|alpha-1,4-N-acetylglucosaminyltransferase EXTL1 [EC:2.4.1.224]" GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane GO:0008375//acetylglucosaminyltransferase activity - gi|172072650|ref|NP_062524.2|/0/exostosin-like 1 [Mus musculus] 81907 3692 0.853333333 2.49 1.544964433 Up 0.639672421 Tmem108 transmembrane protein 108 - GO:0031224//intrinsic component of membrane - - gi|30519983|ref|NP_848753.1|/0/transmembrane protein 108 precursor [Mus musculus] 14114 3359 31.99 43.30333333 0.43685709 Up 0.639446764 Fbln1 fibulin 1 K17307|1|0.0|1482|mmu:14114|fibulin 1/2 GO:0005578//proteinaceous extracellular matrix GO:0008047//enzyme activator activity;GO:0005488//binding GO:0043062//extracellular structure organization;GO:0051345//positive regulation of hydrolase activity gi|168693628|ref|NP_034310.2|/0/fibulin-1 precursor [Mus musculus] 15040 1317 31.38333333 42.68333333 0.443674253 Up 0.639409154 H2-T23 "histocompatibility 2, T region locus 23" "K06751|1|0.0|708|mmu:15040|major histocompatibility complex, class I" GO:0031224//intrinsic component of membrane;GO:0042611 - GO:0002488;GO:0043583//ear development "gi|6754148|ref|NP_034528.1|/0/H-2 class I histocompatibility antigen, D-37 alpha chain precursor [Mus musculus]" 21393 948 1524.663333 2003.956667 0.394360601 Up 0.639108278 Tcap titin-cap K19879|1|6e-92|339|mmu:21393|telethonin GO:0031674//I band GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding GO:0003007//heart morphogenesis;GO:0006941//striated muscle contraction;GO:0014897;GO:0035994//response to muscle stretch;GO:0014866//skeletal myofibril assembly;GO:0048738//cardiac muscle tissue development;GO:0007015//actin filament organization;GO:0009952//anterior/posterior pattern specification;GO:0003299 gi|124248560|ref|NP_035670.2|/4.56034e-91/telethonin [Mus musculus] 100885844 89 0.92 0.01 -6.523561956 Down 0.638779194 Mir5709 microRNA 5709 - - - - - 102466256 139 0.01 0.916666667 6.518325308 Up 0.638779194 Mir8102 microRNA 8102 - - - - - 665622 459 2.873333333 5.27 0.875077593 Up 0.638769792 Hist1h2br histone cluster 1 H2br K11252|1|4e-45|181|cge:100761268|histone H2B GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization "gi|160420310|ref|NP_001091448.2|/1.63672e-46/H2b histone family, member A isoform 1 [Mus musculus]" 665596 459 2.873333333 5.27 0.875077593 Up 0.638769792 Hist1h2bq "histone cluster 1, H2bq" K11252|1|4e-45|181|cge:100761268|histone H2B GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|344238174|gb|EGV94277.1|/3.06937e-44/histone H2B type 1 [Cricetulus griseus] 57278 2407 151.44 200.3833333 0.404016203 Up 0.638675768 Bcam basal cell adhesion molecule K06578|1|0.0|1130|mmu:57278|Lutheran blood group glycoprotein GO:0016021//integral component of membrane;GO:0044464 GO:0004872//receptor activity;GO:0005515//protein binding GO:0031589//cell-substrate adhesion gi|13435987|gb|AAH04826.1|/0/Bcam protein [Mus musculus] 474160 830 3.146666667 5.633333333 0.840164482 Up 0.638045808 Platr17 pluripotency associated transcript 17 K10591|1|4e-06|54.3|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] - - - "gi|148701441|gb|EDL33388.1|/2.3519e-18/mCG1045525, partial [Mus musculus]" 223658 5263.95 12.27333333 8.23 -0.57656279 Down 0.638045808 Mroh1 maestro heat-like repeat family member 1 - - - - "gi|148697618|gb|EDL29565.1|/0/mCG134445, isoform CRA_b, partial [Mus musculus]" 14190 3769 6.463333333 10.01 0.631091671 Up 0.637378239 Fgl2 fibrinogen-like protein 2 K10104|1|4e-55|219|nve:NEMVE_v1g90597|ficolin;K05466|3|1e-50|204|bacu:103002510|angiopoietin 2 - GO:0016787//hydrolase activity GO:0008219//cell death gi|31542814|ref|NP_032039.2|/0/fibroleukin precursor [Mus musculus] 15482 2415 5.256666667 2.873333333 -0.871422886 Down 0.636983339 Hspa1l heat shock protein 1-like K03283|1|0.0|1140|mmu:15482|heat shock 70kDa protein 1/8 GO:0043234//protein complex;GO:0044429 GO:0032550 GO:0050896//response to stimulus;GO:0048869//cellular developmental process;GO:0035036//sperm-egg recognition;GO:0048232//male gamete generation gi|3461869|dbj|BAA32522.1|/0/spermatid-specific heat shock protein 70 [Mus musculus] 93713 4540 0.433333333 1.82 2.070389328 Up 0.636795291 Pcdhga5 "protocadherin gamma subfamily A, 5" K16495|1|0.0|1762|mmu:93713|protocadherin gamma subfamily A GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|18087761|ref|NP_291066.1|/0/protocadherin gamma-A5 precursor [Mus musculus] 57816 942 125.2966667 165.0066667 0.39717628 Up 0.636795291 Tesc tescalcin K17612|1|1e-118|428|ocu:100345622|calcineurin B homologous protein 3 GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0001726//ruffle GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0019887//protein kinase regulator activity;GO:0004857//enzyme inhibitor activity "GO:0006351//transcription, DNA-templated;GO:0031647//regulation of protein stability;GO:0030219//megakaryocyte differentiation;GO:0032526//response to retinoic acid;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0008283//cell proliferation;GO:0030155//regulation of cell adhesion;GO:0006612//protein targeting to membrane;GO:0008406//gonad development;GO:0044092//negative regulation of molecular function;GO:0032415//regulation of sodium:proton antiporter activity" gi|655874715|ref|XP_008270554.1|/9.58216e-118/PREDICTED: LOW QUALITY PROTEIN: calcineurin B homologous protein 3 [Oryctolagus cuniculus] 21822 2809 2.82 5.18 0.877256935 Up 0.63671067 Tgtp1 T cell specific GTPase 1 K17072|1|3e-155|551|mmu:432555|interferon gamma inducible protein 47 - GO:0032550 GO:0035456//response to interferon-beta "gi|148701833|gb|EDL33780.1|/0/T-cell specific GTPase, isoform CRA_a, partial [Mus musculus]" 81840 5722 3.606666667 6.216666667 0.785475131 Up 0.636400391 Sorcs2 sortilin-related VPS10 domain containing receptor 2 K12388|1|3e-61|240|tru:101077962|sortilin GO:0031224//intrinsic component of membrane GO:0008528//G-protein coupled peptide receptor activity GO:0007186//G-protein coupled receptor signaling pathway gi|26006269|dbj|BAC41477.1|/0/mKIAA1329 protein [Mus musculus] 18829 868 21.45666667 29.53666667 0.461081053 Up 0.636184136 Ccl21a chemokine (C-C motif) ligand 21A (serine) K16062|1|9e-57|222|mmu:100504362|C-C motif chemokine 21 GO:0009986//cell surface GO:0005125//cytokine activity GO:0001952//regulation of cell-matrix adhesion;GO:0033627//cell adhesion mediated by integrin;GO:0031346//positive regulation of cell projection organization;GO:0043410//positive regulation of MAPK cascade;GO:0034694//response to prostaglandin;GO:0002408//myeloid dendritic cell chemotaxis;GO:0001934//positive regulation of protein phosphorylation;GO:0007254//JNK cascade;GO:0031269//pseudopodium assembly;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0001767;GO:0051283//negative regulation of sequestering of calcium ion;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0030041//actin filament polymerization;GO:0043066//negative regulation of apoptotic process;GO:0050927//positive regulation of positive chemotaxis gi|14547891|ref|NP_035254.1|/6.93617e-56/C-C motif chemokine 21a precursor [Mus musculus] 212996 4196 2.546666667 4.806666667 0.916426621 Up 0.636174734 Wbscr17 Williams-Beuren syndrome chromosome region 17 homolog (human) K00710|1|0.0|1170|mmu:212996|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008376//acetylgalactosaminyltransferase activity GO:0006464//cellular protein modification process gi|30851362|gb|AAH52469.1|/0/Wbscr17 protein [Mus musculus] 108767 1940 67.33666667 89.54333333 0.411193719 Up 0.635309715 Pnrc1 proline-rich nuclear receptor coactivator 1 K18774|1|7e-131|470|mmu:108767|proline-rich nuclear receptor coactivator 1 - GO:0005488//binding "GO:0006351//transcription, DNA-templated" gi|113461982|ref|NP_001028397.2|/6.2177e-130/proline-rich nuclear receptor coactivator 1 [Mus musculus] 12260 1062 66.83666667 88.94666667 0.412300757 Up 0.635272105 C1qb "complement component 1, q subcomponent, beta polypeptide" K03987|1|3e-105|384|mmu:12260|complement C1q subcomponent subunit B GO:0005615//extracellular space GO:0042802//identical protein binding GO:0007417//central nervous system development;GO:0006955//immune response;GO:0043583//ear development;GO:0031960//response to corticosteroid gi|6753220|ref|NP_033907.1|/2.52872e-104/complement C1q subcomponent subunit B precursor [Mus musculus] 67425 3774 0.356666667 1.703333333 2.255712495 Up 0.635121667 Eps8l1 EPS8-like 1 K17277|1|0.0|1291|mmu:67425|epidermal growth factor receptor kinase substrate 8 GO:0044424;GO:0044424 - - gi|568946480|ref|XP_006540386.1|/0/PREDICTED: epidermal growth factor receptor kinase substrate 8-like protein 1 isoform X2 [Mus musculus] 74376 8280 87.65 65.97 -0.409943986 Down 0.634867802 Myo18b myosin XVIIIb K10362|1|0.0|4354|mmu:74376|myosin XVIII GO:0005737//cytoplasm;GO:0016459//myosin complex;GO:0031981//nuclear lumen GO:0005488//binding - gi|291327510|ref|NP_083177.2|/0/unconventional myosin-XVIIIb [Mus musculus] 16362 2148.4 11.50333333 16.53333333 0.523325647 Up 0.634350671 Irf1 interferon regulatory factor 1 K09444|1|0.0|641|mmu:16362|interferon regulatory factor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding "GO:0042090;GO:0001779//natural killer cell differentiation;GO:0035456//response to interferon-beta;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0070555//response to interleukin-1;GO:0043434//response to peptide hormone;GO:0045066//regulatory T cell differentiation;GO:0032481//positive regulation of type I interferon production;GO:0009612//response to mechanical stimulus;GO:0045064//T-helper 2 cell differentiation;GO:0022402//cell cycle process;GO:0043331//response to dsRNA;GO:0032870//cellular response to hormone stimulus;GO:0019221//cytokine-mediated signaling pathway;GO:0012502//induction of programmed cell death;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045063//T-helper 1 cell differentiation;GO:0043543;GO:0044703;GO:0006366//transcription from RNA polymerase II promoter;GO:0035740//CD8-positive, alpha-beta T cell proliferation;GO:0032526//response to retinoic acid;GO:0034612//response to tumor necrosis factor;GO:0042090;GO:0001779//natural killer cell differentiation;GO:0035456//response to interferon-beta;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0070555//response to interleukin-1;GO:0043434//response to peptide hormone;GO:0045066//regulatory T cell differentiation;GO:0032481//positive regulation of type I interferon production;GO:0009612//response to mechanical stimulus;GO:0045064//T-helper 2 cell differentiation;GO:0022402//cell cycle process;GO:0043331//response to dsRNA;GO:0032870//cellular response to hormone stimulus;GO:0019221//cytokine-mediated signaling pathway;GO:0012502//induction of programmed cell death;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045063//T-helper 1 cell differentiation;GO:0043543;GO:0044703;GO:0006366//transcription from RNA polymerase II promoter;GO:0035740//CD8-positive, alpha-beta T cell proliferation;GO:0032526//response to retinoic acid;GO:0034612//response to tumor necrosis factor;GO:0042090;GO:0001779//natural killer cell differentiation;GO:0035456//response to interferon-beta;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0070555//response to interleukin-1;GO:0043434//response to peptide hormone;GO:0045066//regulatory T cell differentiation;GO:0032481//positive regulation of type I interferon production;GO:0009612//response to mechanical stimulus;GO:0045064//T-helper 2 cell differentiation;GO:0022402//cell cycle process;GO:0043331//response to dsRNA;GO:0032870//cellular response to hormone stimulus;GO:0019221//cytokine-mediated signaling pathway;GO:0012502//induction of programmed cell death;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045063//T-helper 1 cell differentiation;GO:0043543;GO:0044703;GO:0006366//transcription from RNA polymerase II promoter;GO:0035740//CD8-positive, alpha-beta T cell proliferation;GO:0032526//response to retinoic acid;GO:0034612//response to tumor necrosis factor" gi|6680467|ref|NP_032416.1|/0/interferon regulatory factor 1 isoform a [Mus musculus] 100316690 90 0.903333333 0.01 -6.497186541 Down 0.634219038 Mir1932 microRNA 1932 - - - - - 102466836 82 0.01 0.9 6.491853096 Up 0.634219038 Mir7578 microRNA 7578 - - - - - 22259 1816.47 10.51 15.18666667 0.531042577 Up 0.632752266 Nr1h3 "nuclear receptor subfamily 1, group H, member 3" K08536|1|0.0|845|mmu:22259|liver X receptor alpha GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin "GO:0042974//retinoic acid receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0038023//signaling receptor activity;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0042974//retinoic acid receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0038023//signaling receptor activity;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding" GO:0006633//fatty acid biosynthetic process;GO:0006954//inflammatory response;GO:0031325//positive regulation of cellular metabolic process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032846;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0055092//sterol homeostasis;GO:0055090//acylglycerol homeostasis;GO:0002695//negative regulation of leukocyte activation;GO:0006508//proteolysis;GO:0051004;GO:0010878//cholesterol storage;GO:0006907//pinocytosis;GO:0050709//negative regulation of protein secretion;GO:0048545//response to steroid hormone;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0010866//regulation of triglyceride biosynthetic process;GO:0010874//regulation of cholesterol efflux;GO:0032496//response to lipopolysaccharide;GO:0006909//phagocytosis;GO:0006633//fatty acid biosynthetic process;GO:0006954//inflammatory response;GO:0031325//positive regulation of cellular metabolic process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032846;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0055092//sterol homeostasis;GO:0055090//acylglycerol homeostasis;GO:0002695//negative regulation of leukocyte activation;GO:0006508//proteolysis;GO:0051004;GO:0010878//cholesterol storage;GO:0006907//pinocytosis;GO:0050709//negative regulation of protein secretion;GO:0048545//response to steroid hormone;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0010866//regulation of triglyceride biosynthetic process;GO:0010874//regulation of cholesterol efflux;GO:0032496//response to lipopolysaccharide;GO:0006909//phagocytosis "gi|148695599|gb|EDL27546.1|/0/nuclear receptor subfamily 1, group H, member 3, isoform CRA_c, partial [Mus musculus]" 100217461 94 0.886666667 0.01 -6.470319935 Down 0.632141111 Snord89 "small nucleolar RNA, C/D box 89" - - - - - 18175 5375.82 198.7033333 151.9633333 -0.386892811 Down 0.631943661 Nrap nebulin-related anchoring protein K18267|1|0.0|1160|bom:102265134|nebulin - - - gi|569006540|ref|XP_006526809.1|/0/PREDICTED: nebulin-related-anchoring protein isoform X2 [Mus musculus] 224405 2035 7.806666667 4.836666667 -0.690693556 Down 0.631915454 Cyyr1 cysteine and tyrosine-rich protein 1 - - - - gi|74190182|dbj|BAE37209.1|/7.20318e-68/unnamed protein product [Mus musculus] 242608 3205.84 6.156666667 9.51 0.627295881 Up 0.631520554 Podn podocan K08119|1|2e-43|180|cin:100178772|extracellular matrix protein 2 GO:0044421;GO:0031012//extracellular matrix;GO:0044424;GO:0044421;GO:0031012//extracellular matrix;GO:0044424;GO:0044421;GO:0031012//extracellular matrix;GO:0044424 - GO:0016477//cell migration;GO:0008283//cell proliferation;GO:0016477//cell migration;GO:0008283//cell proliferation;GO:0016477//cell migration;GO:0008283//cell proliferation gi|32526861|ref|NP_766462.2|/0/podocan precursor [Mus musculus] 56744 615 7.506666667 11.25333333 0.584108077 Up 0.631172665 Pf4 platelet factor 4 K05407|1|3e-41|170|mmu:56744|platelet factor 4 GO:0032991//macromolecular complex;GO:0031091//platelet alpha granule;GO:0044421 GO:0005125//cytokine activity;GO:0005539//glycosaminoglycan binding GO:0001525//angiogenesis;GO:0019835//cytolysis;GO:0007166//cell surface receptor signaling pathway;GO:0042221//response to chemical;GO:0007599//hemostasis;GO:0010742//macrophage derived foam cell differentiation;GO:0010467//gene expression;GO:0030219//megakaryocyte differentiation;GO:0010558;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0006915//apoptotic process;GO:0050900//leukocyte migration;GO:0006887//exocytosis;GO:0001819//positive regulation of cytokine production;GO:0065003;GO:0001775//cell activation gi|9910486|ref|NP_064316.1|/1.94484e-40/platelet factor 4 precursor [Mus musculus] 72088 2591.38 3.44 1.6 -1.10433666 Down 0.630411072 Ush1c Usher syndrome 1C K16175|1|1e-13|80.9|nve:NEMVE_v1g10117|protein scribble GO:0043232;GO:0005902//microvillus;GO:0031513//nonmotile primary cilium;GO:0016020//membrane;GO:0043232;GO:0005902//microvillus;GO:0031513//nonmotile primary cilium;GO:0016020//membrane;GO:0043232;GO:0005902//microvillus;GO:0031513//nonmotile primary cilium;GO:0016020//membrane;GO:0043232;GO:0044444//cytoplasmic part;GO:0005902//microvillus;GO:0031513//nonmotile primary cilium;GO:0016020//membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0050905//neuromuscular process;GO:0042471//ear morphogenesis;GO:0050954//sensory perception of mechanical stimulus;GO:0060113//inner ear receptor cell differentiation;GO:0051017//actin filament bundle assembly;GO:0007601//visual perception;GO:0050905//neuromuscular process;GO:0042471//ear morphogenesis;GO:0050954//sensory perception of mechanical stimulus;GO:0060113//inner ear receptor cell differentiation;GO:0051017//actin filament bundle assembly;GO:0007601//visual perception;GO:0050905//neuromuscular process;GO:0042471//ear morphogenesis;GO:0050954//sensory perception of mechanical stimulus;GO:0060113//inner ear receptor cell differentiation;GO:0051017//actin filament bundle assembly;GO:0007601//visual perception;GO:0050905//neuromuscular process;GO:0042471//ear morphogenesis;GO:0050954//sensory perception of mechanical stimulus;GO:0060113//inner ear receptor cell differentiation;GO:0051017//actin filament bundle assembly;GO:0044772//mitotic cell cycle phase transition;GO:0007601//visual perception "gi|148690976|gb|EDL22923.1|/0/Usher syndrome 1C homolog (human), isoform CRA_c, partial [Mus musculus]" 69408 1026 9.336666667 6.033333333 -0.629952286 Down 0.629931551 Dnajc17 DnaJ heat shock protein family (Hsp40) member C17 K09537|1|3e-130|467|mmu:69408|DnaJ homolog subfamily C member 17 - - - - 56431 1918 68.59666667 90.33666667 0.397173208 Up 0.629508443 Dstn destrin K10363|1|2e-90|335|mmu:56431|destrin (actin-depolymerizing factor) GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding GO:0030042//actin filament depolymerization gi|9790219|ref|NP_062745.1|/1.80071e-89/destrin [Mus musculus] 94214 3931 13.09 8.91 -0.55496776 Down 0.629461431 Spock2 "sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2" "K08136|1|0.0|768|mmu:94214|sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican)" GO:0031012//extracellular matrix GO:0046872//metal ion binding;GO:0097367//carbohydrate derivative binding GO:0018149//peptide cross-linking;GO:0043062//extracellular structure organization;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0007154//cell communication;GO:0010810//regulation of cell-substrate adhesion gi|16506279|ref|NP_443720.1|/0/testican-2 precursor [Mus musculus] 19376 1537.42 4.26 7.006666667 0.717874833 Up 0.62937681 Rab34 "RAB34, member RAS oncogene family" K07921|1|9e-146|519|mmu:19376|Ras-related protein Rab-34 GO:0030666//endocytic vesicle membrane;GO:0031252//cell leading edge;GO:0005768//endosome;GO:0030666//endocytic vesicle membrane;GO:0031252//cell leading edge;GO:0005768//endosome GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0017076//purine nucleotide binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0017076//purine nucleotide binding GO:0006906//vesicle fusion;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction;GO:0006906//vesicle fusion;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction gi|74227833|dbj|BAE35734.1|/3.9331e-163/unnamed protein product [Mus musculus] 751546 95 0.87 0.01 -6.442943496 Down 0.627891233 Mir374b microRNA 374b - - - - - 16598 1816 59.34666667 78.34666667 0.400704895 Up 0.627251871 Klf2 Kruppel-like factor 2 (lung) K17845|1|8e-140|499|mmu:16598|krueppel-like factor 2 GO:0005622//intracellular GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0048469//cell maturation;GO:0040007//growth;GO:0034614//cellular response to reactive oxygen species;GO:0071417//cellular response to organonitrogen compound;GO:0001818//negative regulation of cytokine production;GO:0010604;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0043009//chordate embryonic development;GO:0034616//response to laminar fluid shear stress;GO:0034612//response to tumor necrosis factor;GO:0014070//response to organic cyclic compound;GO:0048872//homeostasis of number of cells;GO:0070555//response to interleukin-1 gi|1049020|gb|AAA86728.1|/6.75638e-139/Kruppel-like factor LKLF [Mus musculus] 216616 2036 3.576666667 1.723333333 -1.05341389 Down 0.626480876 Efemp1 epidermal growth factor-containing fibulin-like extracellular matrix protein 1 K18262|1|0.0|984|mmu:216616|EGF-containing fibulin-like extracellular matrix protein 1 GO:0031012//extracellular matrix;GO:0044421 GO:0046872//metal ion binding;GO:0070851//growth factor receptor binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity "GO:0006468//protein phosphorylation;GO:0002062//chondrocyte differentiation;GO:0050953//sensory perception of light stimulus;GO:0038127//ERBB signaling pathway;GO:0006351//transcription, DNA-templated" gi|164607147|ref|NP_666127.2|/0/EGF-containing fibulin-like extracellular matrix protein 1 precursor [Mus musculus] 234779 4314 5.333333333 3.016666667 -0.822082208 Down 0.626264621 Plcg2 "phospholipase C, gamma 2" "K05859|1|0.0|2536|mmu:234779|phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]" - - - - 546546 2051 6.596666667 10.01666667 0.602593379 Up 0.625926135 Serpina3h "serine (or cysteine) peptidase inhibitor, clade A, member 3H" "K04525|1|1e-160|458|rno:299279|serpin peptidase inhibitor, clade A" - - - - 66425 1575 170.95 221.8333333 0.375901743 Up 0.625625259 Pcp4l1 Purkinje cell protein 4-like 1 - - - - gi|12833000|dbj|BAB22346.1|/5.38039e-49/unnamed protein product [Mus musculus] 106014 2625.24 3.203333333 5.56 0.795510953 Up 0.625061115 Fam19a5 "family with sequence similarity 19, member A5" - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|913498976|ref|XP_013204340.1|/4.00535e-109/PREDICTED: protein FAM19A5 isoform X1 [Microtus ochrogaster] 20249 4844 5.026666667 2.793333333 -0.84761428 Down 0.625014104 Scd1 stearoyl-Coenzyme A desaturase 1 K00507|1|0.0|689|mmu:20249|stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1] GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0046914//transition metal ion binding;GO:0016215//acyl-CoA desaturase activity GO:0010872//regulation of cholesterol esterification;GO:0042742//defense response to bacterium;GO:0045444//fat cell differentiation;GO:0006631//fatty acid metabolic process;GO:0008366//axon ensheathment;GO:0044126 gi|31543675|ref|NP_033153.2|/0/acyl-CoA desaturase 1 [Mus musculus] 246049 2431 14.16666667 19.75666667 0.479839216 Up 0.624374741 Slc36a2 "solute carrier family 36 (proton/amino acid symporter), member 2" K14209|1|0.0|882|mmu:246049|solute carrier family 36 (proton-coupled amino acid transporter) GO:0031224//intrinsic component of membrane;GO:0044424 GO:0015179//L-amino acid transmembrane transporter activity;GO:0005416//cation:amino acid symporter activity GO:0003333//amino acid transmembrane transport;GO:0015807//L-amino acid transport;GO:0006818//hydrogen transport;GO:0006812//cation transport gi|238624178|ref|NP_694810.2|/0/proton-coupled amino acid transporter 2 [Mus musculus] 11981 3514.23 28.92333333 38.82 0.42456629 Up 0.623406296 Atp9a "ATPase, class II, type 9A" K01530|1|0.0|1948|mmu:11981|phospholipid-translocating ATPase [EC:3.6.3.1] GO:0031224//intrinsic component of membrane;GO:0005769//early endosome;GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0031224//intrinsic component of membrane;GO:0005769//early endosome GO:0032550;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0032550;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0003824//catalytic activity;GO:0032550;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0003824//catalytic activity GO:0015914//phospholipid transport;GO:0006811//ion transport;GO:0006869//lipid transport;GO:0006811//ion transport;GO:0015914//phospholipid transport "gi|49902622|gb|AAH75718.1|/0/Atp9a protein, partial [Mus musculus]" 78754 2341 11.1 7.453333333 -0.574601989 Down 0.623368686 Galnt15 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15 K00710|1|0.0|1179|mmu:78754|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0008376//acetylgalactosaminyltransferase activity - "gi|148692875|gb|EDL24822.1|/0/UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2, isoform CRA_b, partial [Mus musculus]" 100271841 1986.64 4.126666667 2.13 -0.954123478 Down 0.62267291 Uckl1os "uridine-cytidine kinase 1-like 1, opposite strand" - - - - - 235611 8600 8.29 12.14 0.550324415 Up 0.622230998 Plxnb1 plexin B1 K06821|1|0.0|4042|mmu:235611|plexin B - - - "gi|148689398|gb|EDL21345.1|/0/plexin B1, isoform CRA_b, partial [Mus musculus]" 226830 1619 84.09 64.19 -0.389585684 Down 0.621789086 Smyd2 SET and MYND domain containing 2 K11426|1|0.0|894|mmu:226830|SET and MYND domain-containing protein GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0001099//basal RNA polymerase II transcription machinery binding "GO:0006366//transcription from RNA polymerase II promoter;GO:0016571//histone methylation;GO:0008283//cell proliferation;GO:0018022//peptidyl-lysine methylation;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|30840984|ref|NP_081072.1|/0/N-lysine methyltransferase SMYD2 [Mus musculus] 20741 10417 37.33 27.88 -0.421104947 Down 0.621732671 Sptb "spectrin beta, erythrocytic" K06115|1|0.0|4436|mmu:20741|spectrin beta GO:0032991//macromolecular complex;GO:0030864//cortical actin cytoskeleton;GO:0016020//membrane GO:0003779//actin binding;GO:0046983//protein dimerization activity;GO:0005198//structural molecule activity GO:0048534//hematopoietic or lymphoid organ development;GO:0006778//porphyrin-containing compound metabolic process;GO:0030835//negative regulation of actin filament depolymerization "gi|84490394|ref|NP_038703.3|/0/spectrin beta chain, erythrocytic [Mus musculus]" 55932 2620.56 4.376666667 7.073333333 0.69255774 Up 0.621394186 Gbp3 guanylate binding protein 3 K17339|1|9e-18|95.1|loa:LOAG_04490|atlastin [EC:3.6.5.-] - - - - 15531 6088 14.23333333 9.96 -0.515055922 Down 0.621159126 Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 K02576|1|0.0|1704|mmu:15531|heparan sulfate N-deacetylase/N-sulfotransferase NDST1 [EC:3.1.1.- 2.8.2.-] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0034483//heparan sulfate sulfotransferase activity;GO:0016787//hydrolase activity GO:0006952//defense response;GO:0006024//glycosaminoglycan biosynthetic process;GO:0048598//embryonic morphogenesis;GO:0007420//brain development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030166//proteoglycan biosynthetic process;GO:0035601//protein deacylation;GO:0005976//polysaccharide metabolic process gi|42734444|ref|NP_032332.2|/0/bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 [Mus musculus] 723896 89 0.92 2.44 1.407175382 Up 0.620895859 Mir324 microRNA 324 - - - - - 319942 2636 23.05333333 31.15333333 0.434411168 Up 0.620717214 A530016L24Rik RIKEN cDNA A530016L24 gene - GO:0031224//intrinsic component of membrane - - gi|28892925|ref|NP_796013.1|/4.5521e-81/nutritionally-regulated adipose and cardiac-enriched protein [Mus musculus] 67800 2251 235.2266667 304.4833333 0.372311639 Up 0.620143668 Dgat2 diacylglycerol O-acyltransferase 2 K11160|1|0.0|778|mmu:67800|diacylglycerol O-acyltransferase 2 [EC:2.3.1.20 2.3.1.75] GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0042802//identical protein binding;GO:0016411//acylglycerol O-acyltransferase activity GO:0055092//sterol homeostasis;GO:0055082//cellular chemical homeostasis;GO:0055081//anion homeostasis;GO:0006641//triglyceride metabolic process;GO:0035337;GO:0010876//lipid localization;GO:0060612//adipose tissue development;GO:0019400;GO:0034201//response to oleic acid;GO:0034381//plasma lipoprotein particle clearance gi|21739871|emb|CAD38961.1|/0/hypothetical protein [Homo sapiens] 11875 1715 6.51 9.766666667 0.585208715 Up 0.61916582 Art5 ADP-ribosyltransferase 5 K19977|1|3e-178|627|mmu:11875|ADP-ribosyltransferase 5 [EC:2.4.2.31] - "GO:0016763//transferase activity, transferring pentosyl groups;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0016763//transferase activity, transferring pentosyl groups;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0016763//transferase activity, transferring pentosyl groups;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds" GO:0006486//protein glycosylation;GO:0006486//protein glycosylation;GO:0006486//protein glycosylation gi|160837801|ref|NP_031517.2|/2.49955e-177/ecto-ADP-ribosyltransferase 5 precursor [Mus musculus] 213402 4865 6.37 9.62 0.594743522 Up 0.618817932 Armc2 armadillo repeat containing 2 - - - - gi|167900462|ref|NP_001030030.2|/0/armadillo repeat-containing protein 2 [Mus musculus] 17263 3914.57 2.773333333 4.94 0.832890014 Up 0.618686299 Meg3 maternally expressed 3 - - - - - 319272 2547 25.55333333 34.24333333 0.422311647 Up 0.618357215 A130077B15Rik RIKEN cDNA A130077B15 gene K11290|1|4e-15|76.3|rno:317165|template-activating factor I;K10517|4|2e-08|64.3|cfa:485980|zinc finger and BTB domain-containing protein 46 - - - - 20905 2283 8.403333333 12.2 0.53784753 Up 0.618253789 Sts steroid sulfatase K01131|1|0.0|995|mmu:20905|steryl-sulfatase [EC:3.1.6.2] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0043169//cation binding;GO:0008484//sulfuric ester hydrolase activity GO:0006629//lipid metabolic process;GO:0044703;GO:0048545//response to steroid hormone;GO:0009628//response to abiotic stimulus;GO:0008544//epidermis development;GO:0044708//single-organism behavior;GO:0008283//cell proliferation gi|6678175|ref|NP_033319.1|/0/steryl-sulfatase precursor [Mus musculus] 100303644 1909 68.81666667 52.43666667 -0.392182035 Down 0.618234984 C130080G10Rik RIKEN cDNA C130080G10 gene - - - - - 15015 1793 53.15 69.46333333 0.386181951 Up 0.618197375 H2-Q4 "histocompatibility 2, Q region locus 4" "K06751|1|0.0|654|mmu:15015|major histocompatibility complex, class I" GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0042611 GO:0003823//antigen binding GO:0002252;GO:0001819//positive regulation of cytokine production;GO:0002428 "gi|219521935|ref|NP_001137161.1|/0/histocompatibility 2, Q region locus 4 precursor [Mus musculus] " 102545 1158 6.133333333 9.276666667 0.596935142 Up 0.617172515 Cmtm7 CKLF-like MARVEL transmembrane domain containing 7 - GO:0031224//intrinsic component of membrane;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0044421 GO:0005102//receptor binding;GO:0005102//receptor binding GO:0042221//response to chemical;GO:0042221//response to chemical gi|74198935|dbj|BAE30687.1|/3.61686e-103/unnamed protein product [Mus musculus] 12257 871 13.69333333 18.97333333 0.47049948 Up 0.616486141 Tspo translocator protein K05770|1|1e-99|365|mmu:12257|benzodiazapine receptor GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane GO:0030594//neurotransmitter receptor activity;GO:0005488//binding GO:0032496//response to lipopolysaccharide;GO:0032846;GO:0033555//multicellular organismal response to stress;GO:0010243//response to organonitrogen compound;GO:0070265//necrotic cell death;GO:0001818//negative regulation of cytokine production;GO:0006816//calcium ion transport;GO:0015698//inorganic anion transport;GO:0006694//steroid biosynthetic process;GO:0006915//apoptotic process;GO:0048545//response to steroid hormone;GO:0008285//negative regulation of cell proliferation;GO:0006809//nitric oxide biosynthetic process;GO:0008284//positive regulation of cell proliferation;GO:0010043//response to zinc ion;GO:0031103//axon regeneration;GO:0006971//hypotonic response;GO:0072593//reactive oxygen species metabolic process;GO:0035270//endocrine system development;GO:0016477//cell migration;GO:0044708//single-organism behavior gi|163838662|ref|NP_033905.3|/8.65302e-99/translocator protein [Mus musculus] 240667 3923 8.27 5.356666667 -0.626551806 Down 0.616251081 Sec31b Sec31 homolog B (S. cerevisiae) K14005|1|0.0|2187|mmu:240667|protein transport protein SEC31 - - - gi|133504851|ref|NP_001028515.1|/0/protein transport protein Sec31B [Mus musculus] 56520 863 5.593333333 8.573333333 0.616147927 Up 0.616213472 Nme4 NME/NM23 nucleoside diphosphate kinase 4 K00940|1|5e-105|382|mmu:56520|nucleoside-diphosphate kinase [EC:2.7.4.6] GO:0032155;GO:0005816//spindle pole body;GO:0005768//endosome;GO:0030529//intracellular ribonucleoprotein complex "GO:0032550;GO:0046872//metal ion binding;GO:0031267//small GTPase binding;GO:0042802//identical protein binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0044763;GO:0009209;GO:0010467//gene expression;GO:0009152//purine ribonucleotide biosynthetic process;GO:0016192//vesicle-mediated transport;GO:0009132//nucleoside diphosphate metabolic process "gi|569001119|ref|XP_006524740.1|/2.31943e-104/PREDICTED: nucleoside diphosphate kinase, mitochondrial isoform X2 [Mus musculus]" 14127 683 12.48666667 17.39666667 0.478422502 Up 0.615837376 Fcer1g "Fc receptor, IgE, high affinity I, gamma polypeptide" "K07983|1|2e-40|167|mmu:14127|Fc receptor, IgE, high affinity I, gamma polypeptide" GO:0009986//cell surface;GO:0032997;GO:0016021//integral component of membrane GO:0019763//immunoglobulin receptor activity;GO:0019865//immunoglobulin binding GO:0033024;GO:0001802;GO:0002429//immune response-activating cell surface receptor signaling pathway;GO:0001794;GO:0030168//platelet activation;GO:0030595//leukocyte chemotaxis;GO:0001819//positive regulation of cytokine production;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0001810;GO:0002442;GO:0033008;GO:0038093//Fc receptor signaling pathway;GO:0002478;GO:0032762//mast cell cytokine production;GO:0006909//phagocytosis gi|6753830|ref|NP_034315.1|/1.23446e-39/high affinity immunoglobulin epsilon receptor subunit gamma precursor [Mus musculus] 22229 2448 70.11666667 90.94666667 0.37526335 Up 0.61577156 Ucp3 "uncoupling protein 3 (mitochondrial, proton carrier)" "K15103|1|9e-177|623|mmu:22229|solute carrier family 25 (mitochondrial uncoupling protein), member 8/9" GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0005740//mitochondrial envelope GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006818//hydrogen transport;GO:0044763;GO:0000302//response to reactive oxygen species;GO:0031667//response to nutrient levels;GO:0032787//monocarboxylic acid metabolic process;GO:0044767//single-organism developmental process;GO:0043434//response to peptide hormone;GO:0031960//response to corticosteroid gi|6678495|ref|NP_033490.1|/7.62572e-176/mitochondrial uncoupling protein 3 [Mus musculus] 17105 1057 121.9633333 157.2833333 0.366918317 Up 0.615160405 Lyz2 lysozyme 2 K13915|1|1e-77|292|mmu:17105|lysozyme C [EC:3.2.1.17] - - - - 69847 4148 7.216666667 10.66333333 0.563253968 Up 0.614840724 Wnk4 WNK lysine deficient protein kinase 4 K08867|1|0.0|1631|mmu:69847|WNK lysine deficient protein kinase [EC:2.7.11.1] GO:0043296//apical junction complex;GO:0044424 GO:0032550;GO:0004672//protein kinase activity GO:0035556//intracellular signal transduction;GO:0006464//cellular protein modification process;GO:0015698//inorganic anion transport;GO:0006796//phosphate-containing compound metabolic process;GO:0033036;GO:0051048//negative regulation of secretion;GO:0030320//cellular monovalent inorganic anion homeostasis gi|28316732|ref|NP_783569.1|/0/serine/threonine-protein kinase WNK4 [Mus musculus] 80981 1397 9.736666667 13.84333333 0.507691514 Up 0.614784309 Arl4d ADP-ribosylation factor-like 4D K07945|1|1e-101|372|rno:303559|ADP-ribosylation factor-like protein 4 GO:0031981//nuclear lumen;GO:0016020//membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0015031//protein transport;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction gi|13384792|ref|NP_079680.1|/1.14181e-100/ADP-ribosylation factor-like protein 4D [Mus musculus] 399101 437 11.71 8.076666667 -0.535909172 Down 0.61407913 Snhg3 small nucleolar RNA host gene 3 - - - - - 67971 1040 31.03666667 23.22 -0.418605648 Down 0.613740645 Tppp3 tubulin polymerization-promoting protein family member 3 K20027|1|3e-17|91.7|nle:100594932|palmitoyltransferase ZDHHC1/11 [EC:2.3.1.225] GO:0015630//microtubule cytoskeleton GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding GO:0000226//microtubule cytoskeleton organization gi|685613849|ref|XP_009194938.1|/9.33695e-96/PREDICTED: tubulin polymerization-promoting protein family member 3 isoform X1 [Papio anubis] 14611 2670.03 7.59 11.10333333 0.548821063 Up 0.613590206 Gja3 "gap junction protein, alpha 3" "K07612|1|0.0|803|mmu:14611|gap junction protein, alpha 3" GO:0005921//gap junction;GO:0031224//intrinsic component of membrane;GO:0005921//gap junction;GO:0031224//intrinsic component of membrane GO:0005515//protein binding;GO:0022829//wide pore channel activity;GO:0005515//protein binding;GO:0022829//wide pore channel activity GO:0051234//establishment of localization;GO:0044763;GO:0009628//response to abiotic stimulus;GO:0000302//response to reactive oxygen species;GO:0051234//establishment of localization;GO:0044763;GO:0009628//response to abiotic stimulus;GO:0000302//response to reactive oxygen species gi|59710097|ref|NP_058671.2|/0/gap junction alpha-3 protein precursor [Mus musculus] 252837 2109 6.443333333 3.973333333 -0.697457402 Down 0.61293204 Ackr4 atypical chemokine receptor 4 K04186|1|3e-174|614|mmu:252837|C-C chemokine receptor-like 1 - - - - 50915 1978 123.88 95.68 -0.372653993 Down 0.61269698 Grb14 growth factor receptor bound protein 14 K20064|1|7e-164|580|lcm:102352775|growth factor receptor-bound protein 10 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane;GO:0012505//endomembrane system "GO:0030674//protein binding, bridging;GO:0008289//lipid binding" GO:0008286//insulin receptor signaling pathway;GO:0002376//immune system process;GO:0007599//hemostasis gi|7710032|ref|NP_057928.1|/0/growth factor receptor-bound protein 14 [Mus musculus] 106869 3266.28 8.336666667 11.99666667 0.525091045 Up 0.61167212 Tnfaip8 "tumor necrosis factor, alpha-induced protein 8" - - - - - 12922 2695.63 12.75 17.65666667 0.469715761 Up 0.611568694 Crhr2 corticotropin releasing hormone receptor 2 K04579|1|0.0|750|cge:100774100|corticotropin releasing hormone receptor 2 GO:0031224//intrinsic component of membrane;GO:0033267;GO:0005783//endoplasmic reticulum;GO:0043025//neuronal cell body;GO:0031224//intrinsic component of membrane;GO:0033267;GO:0005783//endoplasmic reticulum;GO:0043025//neuronal cell body;GO:0031224//intrinsic component of membrane;GO:0033267;GO:0005783//endoplasmic reticulum;GO:0043025//neuronal cell body;GO:0031224//intrinsic component of membrane;GO:0033267;GO:0005783//endoplasmic reticulum;GO:0043025//neuronal cell body GO:0005102//receptor binding;GO:0004930//G-protein coupled receptor activity;GO:0042277//peptide binding;GO:0005102//receptor binding;GO:0004930//G-protein coupled receptor activity;GO:0042277//peptide binding;GO:0005102//receptor binding;GO:0004930//G-protein coupled receptor activity;GO:0042277//peptide binding;GO:0005102//receptor binding;GO:0004930//G-protein coupled receptor activity;GO:0042277//peptide binding GO:0002027//regulation of heart rate;GO:0032277//negative regulation of gonadotropin secretion;GO:0007631//feeding behavior;GO:0032275//luteinizing hormone secretion;GO:0048167//regulation of synaptic plasticity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0001820//serotonin secretion;GO:0022600//digestive system process;GO:0009967//positive regulation of signal transduction;GO:0008217//regulation of blood pressure;GO:0043435;GO:0007600//sensory perception;GO:0001819//positive regulation of cytokine production;GO:0014060;GO:0032872//regulation of stress-activated MAPK cascade;GO:0030154//cell differentiation;GO:0009968//negative regulation of signal transduction;GO:0034766//negative regulation of ion transmembrane transport;GO:0006584//catecholamine metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0030421//defecation;GO:0030036//actin cytoskeleton organization;GO:0006171//cAMP biosynthetic process;GO:0007519//skeletal muscle tissue development;GO:0014061//regulation of norepinephrine secretion;GO:0002027//regulation of heart rate;GO:0032277//negative regulation of gonadotropin secretion;GO:0007631//feeding behavior;GO:0032275//luteinizing hormone secretion;GO:0048167//regulation of synaptic plasticity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0001820//serotonin secretion;GO:0022600//digestive system process;GO:0009967//positive regulation of signal transduction;GO:0008217//regulation of blood pressure;GO:0043435;GO:0007600//sensory perception;GO:0001819//positive regulation of cytokine production;GO:0014060;GO:0032872//regulation of stress-activated MAPK cascade;GO:0030154//cell differentiation;GO:0009968//negative regulation of signal transduction;GO:0034766//negative regulation of ion transmembrane transport;GO:0006584//catecholamine metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0030421//defecation;GO:0030036//actin cytoskeleton organization;GO:0006171//cAMP biosynthetic process;GO:0007519//skeletal muscle tissue development;GO:0014061//regulation of norepinephrine secretion;GO:0002027//regulation of heart rate;GO:0032277//negative regulation of gonadotropin secretion;GO:0007631//feeding behavior;GO:0032275//luteinizing hormone secretion;GO:0048167//regulation of synaptic plasticity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0022037//metencephalon development;GO:0051384//response to glucocorticoid;GO:0001820//serotonin secretion;GO:0022600//digestive system process;GO:0009967//positive regulation of signal transduction;GO:0008217//regulation of blood pressure;GO:0043435;GO:0007600//sensory perception;GO:0021536//diencephalon development;GO:0001819//positive regulation of cytokine production;GO:0014060;GO:0032872//regulation of stress-activated MAPK cascade;GO:0030154//cell differentiation;GO:0009968//negative regulation of signal transduction;GO:0034766//negative regulation of ion transmembrane transport;GO:0006584//catecholamine metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0030421//defecation;GO:0030036//actin cytoskeleton organization;GO:0006171//cAMP biosynthetic process;GO:0007519//skeletal muscle tissue development;GO:0014061//regulation of norepinephrine secretion;GO:0002027//regulation of heart rate;GO:0032277//negative regulation of gonadotropin secretion;GO:0007631//feeding behavior;GO:0032275//luteinizing hormone secretion;GO:0048167//regulation of synaptic plasticity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0022037//metencephalon development;GO:0051384//response to glucocorticoid;GO:0001820//serotonin secretion;GO:0022600//digestive system process;GO:0009967//positive regulation of signal transduction;GO:0008217//regulation of blood pressure;GO:0043435;GO:0007600//sensory perception;GO:0021536//diencephalon development;GO:0001819//positive regulation of cytokine production;GO:0014060;GO:0032872//regulation of stress-activated MAPK cascade;GO:0030154//cell differentiation;GO:0009968//negative regulation of signal transduction;GO:0034766//negative regulation of ion transmembrane transport;GO:0006584//catecholamine metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0030421//defecation;GO:0030036//actin cytoskeleton organization;GO:0006171//cAMP biosynthetic process;GO:0007519//skeletal muscle tissue development;GO:0014061//regulation of norepinephrine secretion gi|568599834|ref|NP_001275548.1|/0/corticotropin-releasing factor receptor 2 isoform 3 precursor [Mus musculus] 230163 2018 3.053333333 1.423333333 -1.101111528 Down 0.61147467 Aldob "aldolase B, fructose-bisphosphate" "K01623|1|0.0|691|mmu:230163|fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" - - - - 20305 1436 21.71666667 29.12666667 0.423537927 Up 0.611371244 Ccl6 chemokine (C-C motif) ligand 6 K05510|1|5e-62|241|mmu:20305|C-C motif chemokine 6/9;K05511|3|2e-39|166|cge:100769898|C-C motif chemokine 15/23 GO:0044421 GO:0048020//CCR chemokine receptor binding;GO:0005125//cytokine activity GO:0006935//chemotaxis;GO:0002376//immune system process;GO:0012501//programmed cell death gi|6677883|ref|NP_033165.1|/4.13189e-61/C-C motif chemokine 6 precursor [Mus musculus] 735271 88 0.01 0.796666667 6.315904307 Up 0.611352439 Mir709 microRNA 709 - - - - - 18035 1592 53.04666667 69.08 0.381005985 Up 0.611220806 Nfkbia "nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha" K04734|1|3e-171|603|mmu:18035|NF-kappa-B inhibitor alpha GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0008134//transcription factor binding;GO:0005048//signal sequence binding;GO:0044389//ubiquitin-like protein ligase binding GO:0010883//regulation of lipid storage;GO:0031325//positive regulation of cellular metabolic process;GO:0010742//macrophage derived foam cell differentiation;GO:0043331//response to dsRNA;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0030099//myeloid cell differentiation;GO:0007219//Notch signaling pathway;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0002237//response to molecule of bacterial origin;GO:1901652//response to peptide;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0002224//toll-like receptor signaling pathway;GO:0010874//regulation of cholesterol efflux "gi|148704779|gb|EDL36726.1|/2.5251e-171/nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha, partial [Mus musculus]" 11826 2760 235.99 183.7133333 -0.361269391 Down 0.611089172 Aqp1 aquaporin 1 K09864|1|1e-147|526|mmu:11826|aquaporin-1 - - - - 20715 2030 1.24 2.8 1.175086707 Up 0.610976344 Serpina3g "serine (or cysteine) peptidase inhibitor, clade A, member 3G" "K04525|1|0.0|785|mmu:20715|serpin peptidase inhibitor, clade A" - GO:0004857//enzyme inhibitor activity GO:0009725//response to hormone;GO:0051346//negative regulation of hydrolase activity gi|86476056|ref|NP_033277.1|/0/serine protease inhibitor A3G [Mus musculus] 18553 4282.98 29.32 21.98 -0.415693717 Down 0.610901125 Pcsk6 proprotein convertase subtilisin/kexin type 6 K08672|1|0.0|1852|mmu:18553|proprotein convertase subtilisin/kexin type 6 [EC:3.4.21.-] - - - gi|599044042|ref|NP_001278113.1|/0/proprotein convertase subtilisin/kexin type 6 isoform 2 precursor [Mus musculus] 18769 1081.1 165.3 212.8533333 0.364772959 Up 0.610478017 Pkig "protein kinase inhibitor, gamma" K15985|1|1e-06|56.6|cmk:103190697|cAMP-dependent protein kinase inhibitor alpha - - - - 633640 1305.45 11.66 16.22666667 0.476798879 Up 0.610478017 Gm7120 transmembrane protein 267 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148686393|gb|EDL18340.1|/3.03814e-163/mCG114452, partial [Mus musculus]" 14115 4427.74 40.80666667 30.95333333 -0.398710087 Down 0.610431005 Fbln2 fibulin 2 K17307|1|0.0|2207|mmu:14115|fibulin 1/2 GO:0031012//extracellular matrix;GO:0031012//extracellular matrix GO:0005488//binding;GO:0005488//binding GO:0010810//regulation of cell-substrate adhesion;GO:0010810//regulation of cell-substrate adhesion gi|124517693|ref|NP_001074906.1|/0/fibulin-2 isoform b precursor [Mus musculus] 20324 3069 48.49666667 36.95666667 -0.392050952 Down 0.610101922 Sdpr serum deprivation response K19387|1|3e-56|223|tup:102481859|polymerase I and transcript release factor GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044444//cytoplasmic part GO:0005543//phospholipid binding GO:0006366//transcription from RNA polymerase II promoter gi|20270267|ref|NP_620080.1|/0/serum deprivation-response protein [Mus musculus] 12549 7722 14 9.89 -0.501384401 Down 0.610092519 Arhgap31 Rho GTPase activating protein 31 K17933|1|3e-81|307|gja:107108176|Rho GTPase-activating protein 33 GO:0005924//cell-substrate adherens junction;GO:0031252//cell leading edge;GO:0044444//cytoplasmic part GO:0008047//enzyme activator activity;GO:0019904//protein domain specific binding GO:0007264//small GTPase mediated signal transduction gi|55770848|ref|NP_064656.2|/0/rho GTPase-activating protein 31 [Mus musculus] 19125 2283 16.86333333 22.8 0.435144086 Up 0.609772838 Prodh proline dehydrogenase K00318|1|0.0|1077|mmu:19125|proline dehydrogenase [EC:1.5.-.-] GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane "GO:0050660//flavin adenine dinucleotide binding;GO:0016645//oxidoreductase activity, acting on the CH-NH group of donors" GO:0006560//proline metabolic process;GO:0006536//glutamate metabolic process "gi|118601004|ref|NP_035302.2|/0/proline dehydrogenase 1, mitochondrial precursor [Mus musculus]" 218763 1676 6.143333333 9.183333333 0.579996248 Up 0.609763436 Lrrc3b leucine rich repeat containing 3B K06839|1|5e-16|88.6|sko:102806385|slit 2;K06850|3|2e-15|86.3|dre:80354|slit 3 GO:0031224//intrinsic component of membrane - - gi|22122541|ref|NP_666164.1|/9.37816e-148/leucine-rich repeat-containing protein 3B precursor [Mus musculus] 19188 899.14 36.79333333 48.09666667 0.386492527 Up 0.609528376 Psme2 "proteasome (prosome, macropain) activator subunit 2 (PA28 beta)" K06697|1|4e-122|439|mmu:621823|proteasome activator subunit 2 (PA28 beta) - GO:0061135;GO:0061135 GO:0010952//positive regulation of peptidase activity;GO:0019882//antigen processing and presentation;GO:0010952//positive regulation of peptidase activity;GO:0019882//antigen processing and presentation gi|20137004|ref|NP_035320.1|/2.97894e-121/proteasome activator complex subunit 2 isoform 1 [Mus musculus] 21366 6169 39.26 29.69666667 -0.40275917 Down 0.609377938 Slc6a6 "solute carrier family 6 (neurotransmitter transporter, taurine), member 6" "K05039|1|0.0|1176|mmu:21366|solute carrier family 6 (neurotransmitter transporter, GABA) member 6/8/11/12/13" GO:0016021//integral component of membrane GO:1901682;GO:1901681;GO:0005343//organic acid:sodium symporter activity;GO:0005326//neurotransmitter transporter activity GO:0044763;GO:0015804//neutral amino acid transport gi|31982828|ref|NP_033346.2|/0/sodium- and chloride-dependent taurine transporter [Mus musculus] 100526461 98 0.786666667 0.01 -6.297680549 Down 0.608870209 Mir1249 microRNA 1249 - - - - - 15216 1722 14.74333333 20.14333333 0.4502397 Up 0.608682162 Hfe hemochromatosis "K11253|1|7e-128|460|pps:100989495|histone H3;K06751|2|8e-59|230|ssc:100626428|major histocompatibility complex, class I" GO:0031224//intrinsic component of membrane;GO:0042611;GO:0005768//endosome;GO:0031982//vesicle;GO:0005902//microvillus GO:0005515//protein binding GO:0044703;GO:0009267//cellular response to starvation;GO:0009058//biosynthetic process;GO:0034755//iron ion transmembrane transport;GO:0006875//cellular metal ion homeostasis;GO:0002376//immune system process;GO:0048871//multicellular organismal homeostasis gi|31981697|ref|NP_034554.2|/0/hereditary hemochromatosis protein homolog precursor [Mus musculus] 12010 858 896.62 1146.223333 0.354319585 Up 0.608174433 B2m beta-2 microglobulin K08055|1|4e-57|223|mmu:12010|beta-2-microglobulin GO:0042611;GO:0009986//cell surface;GO:0044421 GO:0005488//binding GO:0006952//defense response;GO:0010038//response to metal ion;GO:0006457//protein folding;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0030217//T cell differentiation;GO:0002477//antigen processing and presentation of exogenous peptide antigen via MHC class Ib;GO:0009607//response to biotic stimulus gi|31981890|ref|NP_033865.2|/3.05082e-56/beta-2-microglobulin precursor [Mus musculus] 16599 2314 14.23666667 10.10666667 -0.494304144 Down 0.606829892 Klf3 Kruppel-like factor 3 (basic) K15605|1|6e-170|600|mmu:16599|krueppel-like factor 3 - - - - 93677 1967 534.7833333 419.3166667 -0.35091433 Down 0.606529016 Lmod2 leiomodin 2 (cardiac) K10370|1|1e-39|167|shr:100931294|tropomodulin - GO:0008092//cytoskeletal protein binding - gi|74315957|ref|NP_444328.1|/0/leiomodin-2 [Mus musculus] 104086 1936 14.14 19.33666667 0.451556998 Up 0.606340968 Cyp27a1 "cytochrome P450, family 27, subfamily a, polypeptide 1" K00488|1|0.0|1032|mmu:104086|cholestanetriol 26-monooxygenase [EC:1.14.15.15] - - - - 16988 418 1.283333333 2.823333333 1.137503524 Up 0.605823837 Lst1 leukocyte specific transcript 1 - - - - - 260299 2155 10.65 7.333333333 -0.538312407 Down 0.605532363 Cadm4 cell adhesion molecule 4 K06783|1|0.0|745|mmu:260299|cell adhesion molecule 4 - - - - 114564 2719 1.42 3.006666667 1.082274003 Up 0.605513558 Csprs component of Sp100-rs K08432|1|7e-11|72.4|xtr:100491772|G protein-coupled receptor 148;K04257|3|6e-09|65.9|ola:101171968|olfactory receptor - - - gi|568907745|ref|XP_006496584.1|/4.3057e-159/PREDICTED: component of Sp100-rs-like isoform X2 [Mus musculus] 66599 1098 15.44333333 20.98333333 0.442259696 Up 0.605475949 Rdm1 RAD52 motif 1 K10874|1|1e-148|528|mmu:66599|RAD52 motif-containing protein 1 GO:0016604//nuclear body GO:0036094//small molecule binding;GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process gi|13385116|ref|NP_079930.1|/1.14076e-147/RAD52 motif-containing protein 1 [Mus musculus] 66060 595 58.58333333 75.71333333 0.370057102 Up 0.605325511 Cystm1 cysteine-rich transmembrane module containing 1 - - - - gi|537236332|gb|ERE85579.1|/3.99017e-24/hypothetical protein H671_2g5148 [Cricetulus griseus] 102634559 407 5.646666667 8.506666667 0.591194454 Up 0.605250291 Gm29443 predicted gene 29443 - - - - - 327959 2549.9 9.31 6.263333333 -0.571850507 Down 0.605043439 Xaf1 XIAP associated factor 1 - - - - gi|599044791|ref|NP_001278082.1|/1.68075e-100/XIAP-associated factor 1 isoform 2 [Mus musculus] 12684 1186 7.2 4.63 -0.636984713 Down 0.604921208 Cideb "cell death-inducing DNA fragmentation factor, alpha subunit-like effector B" - GO:0044444//cytoplasmic part - GO:0012502//induction of programmed cell death gi|162138890|ref|NP_034024.2|/1.34665e-104/cell death activator CIDE-B [Mus musculus] 117198 3443.22 317.6 249.4666667 -0.348363855 Down 0.604657941 Ivns1abp influenza virus NS1A binding protein K15046|1|0.0|1300|mmu:117198|influenza virus NS1A-binding protein GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 - GO:0006915//apoptotic process;GO:0006915//apoptotic process;GO:0006915//apoptotic process gi|37360122|dbj|BAC98039.1|/0/mKIAA0850 protein [Mus musculus] 100526514 82 0.01 0.77 6.266786541 Up 0.604103201 Mir3112 microRNA 3112 - - - - - 100217441 99 0.773333333 0.01 -6.273018494 Down 0.604103201 Snord23 "small nucleolar RNA, C/D box 23" - - - - - 14282 3783 2.436666667 1.003333333 -1.280107919 Down 0.604074993 Fosb FBJ osteosarcoma oncogene B K09029|1|1e-135|480|tup:102483965|protein FosB - GO:0003677//DNA binding;GO:0005515//protein binding GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter;GO:0051592//response to calcium ion gi|947205153|ref|XP_014438515.1|/9.98979e-135/PREDICTED: protein fosB [Tupaia chinensis] 724063 98 0.01 0.766666667 6.26052755 Up 0.604037384 Mir330 microRNA 330 - - - - - 16792 2402 22.34 29.69 0.410347908 Up 0.60351085 Laptm5 lysosomal-associated protein transmembrane 5 K12387|1|6e-146|520|mmu:16792|lysosomal-associated transmembrane protein GO:0005764//lysosome;GO:0016021//integral component of membrane - GO:0051234//establishment of localization gi|74215128|dbj|BAE41796.1|/6.57514e-148/unnamed protein product [Mus musculus] 553127 1246 52.47333333 67.89333333 0.371685479 Up 0.603388619 Cxx1b CAAX box 1B - - - - gi|21313590|ref|NP_077132.1|/1.2868e-52/mammalian retrotransposon derived 8b [Mus musculus] 626049 574 0.413333333 1.61 1.961683068 Up 0.603360412 Gm20753 "predicted gene, 20753" - - - - - 231430 1338 7.97 11.44 0.521435423 Up 0.602777464 Cox18 cytochrome c oxidase assembly protein 18 K17797|1|3e-159|444|mmu:231430|mitochondrial inner membrane protein COX18 GO:0031304//intrinsic component of mitochondrial inner membrane;GO:0031304//intrinsic component of mitochondrial inner membrane;GO:0031304//intrinsic component of mitochondrial inner membrane GO:0022892//substrate-specific transporter activity;GO:0022892//substrate-specific transporter activity;GO:0022892//substrate-specific transporter activity GO:0045184//establishment of protein localization;GO:0007006//mitochondrial membrane organization;GO:0043623//cellular protein complex assembly;GO:0045184//establishment of protein localization;GO:0007006//mitochondrial membrane organization;GO:0043623//cellular protein complex assembly;GO:0045184//establishment of protein localization;GO:0007006//mitochondrial membrane organization;GO:0043623//cellular protein complex assembly gi|254540218|ref|NP_001028482.2|/1.17245e-163/mitochondrial inner membrane protein COX18 isoform 2 [Mus musculus] 107976 1293.43 29.69666667 39.04666667 0.39489839 Up 0.602711648 Bre brain and reproductive organ-expressed protein K12173|1|0.0|714|mmu:107976|BRCA1-A complex subunit BRE GO:0043231//intracellular membrane-bounded organelle;GO:0000151//ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000151//ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000151//ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000151//ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000151//ubiquitin ligase complex GO:0005048//signal sequence binding;GO:0043130//ubiquitin binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0043130//ubiquitin binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0043130//ubiquitin binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0043130//ubiquitin binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0043130//ubiquitin binding;GO:0032813//tumor necrosis factor receptor superfamily binding GO:0009314//response to radiation;GO:0012501//programmed cell death;GO:0006281//DNA repair;GO:0000077//DNA damage checkpoint;GO:0006325//chromatin organization;GO:0007154//cell communication;GO:0009314//response to radiation;GO:0012501//programmed cell death;GO:0006281//DNA repair;GO:0000077//DNA damage checkpoint;GO:0006325//chromatin organization;GO:0009314//response to radiation;GO:0012501//programmed cell death;GO:0006281//DNA repair;GO:0000077//DNA damage checkpoint;GO:0006325//chromatin organization;GO:0009314//response to radiation;GO:0012501//programmed cell death;GO:0006281//DNA repair;GO:0000077//DNA damage checkpoint;GO:0006325//chromatin organization;GO:0009314//response to radiation;GO:0012501//programmed cell death;GO:0006281//DNA repair;GO:0000077//DNA damage checkpoint;GO:0006325//chromatin organization gi|21617851|ref|NP_653124.1|/0/BRCA1-A complex subunit BRE isoform V [Mus musculus] 15019 1009 9.716666667 13.62666667 0.487899313 Up 0.60248599 H2-Q8 "histocompatibility 2, Q region locus 8" "K06751|1|0.0|656|mmu:15019|major histocompatibility complex, class I" GO:0031224//intrinsic component of membrane;GO:0042611;GO:0009986//cell surface GO:0005515//protein binding;GO:0003823//antigen binding GO:0002484;GO:0001819//positive regulation of cytokine production;GO:0002664//regulation of T cell tolerance induction;GO:0002252;GO:0009581;GO:0002428 "gi|389595436|ref|NP_075613.3|/0/H-2 class I histocompatibility antigen, Q8 alpha chain precursor [Mus musculus]" 20496 6520 5.603333333 3.396666667 -0.722165673 Down 0.602316748 Slc12a2 "solute carrier family 12, member 2" "K10951|1|0.0|2048|mmu:20496|solute carrier family 12 (sodium/potassium/chloride transporter), member 2" GO:0031224//intrinsic component of membrane;GO:0044459 GO:0015377//cation:chloride symporter activity GO:0015696//ammonium transport;GO:0048754//branching morphogenesis of an epithelial tube;GO:0060560//developmental growth involved in morphogenesis;GO:0006970//response to osmotic stress;GO:0006821//chloride transport;GO:0007186//G-protein coupled receptor signaling pathway;GO:0050877//neurological system process;GO:0030001//metal ion transport;GO:0006884//cell volume homeostasis gi|124517716|ref|NP_033220.2|/0/solute carrier family 12 member 2 [Mus musculus] 102466152 104 0.756666667 0.01 -6.241585987 Down 0.601479935 Mir6357 microRNA 6357 K03510|1|2e-11|69.7|mmu:26447|DNA polymerase iota [EC:2.7.7.7] - - - gi|575501682|ref|NP_001276444.1|/1.70123e-10/DNA polymerase iota isoform 3 [Mus musculus] 100040531 804.84 3.86 6.166666667 0.675890017 Up 0.600520892 Dynlt1f dynein light chain Tctex-type 1F K10420|1|1e-59|231|mmu:21648|dynein light chain Tctex-type 1 GO:0043231//intracellular membrane-bounded organelle;GO:0030286//dynein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0030286//dynein complex GO:0005515//protein binding;GO:0003774//motor activity;GO:0005515//protein binding;GO:0003774//motor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0031175//neuron projection development;GO:0006886//intracellular protein transport;GO:0040001//establishment of mitotic spindle localization;GO:0010721//negative regulation of cell development;GO:0019048//modulation by virus of host morphology or physiology;GO:0000087//mitotic M phase;GO:0007186//G-protein coupled receptor signaling pathway;GO:0031175//neuron projection development;GO:0006886//intracellular protein transport;GO:0040001//establishment of mitotic spindle localization;GO:0010721//negative regulation of cell development;GO:0019048//modulation by virus of host morphology or physiology;GO:0000087//mitotic M phase gi|315711043|ref|NP_001186877.1|/4.74159e-55/dynein light chain Tctex-type 1F isoform 2 [Mus musculus] 215418 2890 11.04 15.28666667 0.469533682 Up 0.600408063 Csrnp1 cysteine-serine-rich nuclear protein 1 K17494|1|0.0|886|mmu:215418|cysteine/serine-rich nuclear protein GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001501//skeletal system development;GO:0009653//anatomical structure morphogenesis;GO:0006366//transcription from RNA polymerase II promoter gi|568963668|ref|XP_006512098.1|/0/PREDICTED: cysteine/serine-rich nuclear protein 1 isoform X2 [Mus musculus] 67523 997 3.823333333 2.036666667 -0.908621106 Down 0.600295235 1700094J05Rik RIKEN cDNA 1700094J05 gene K16481|1|5e-22|107|mmu:18541|pericentrin - - - - 106878 2008 2.393333333 4.296666667 0.844196515 Up 0.600238821 Smim3 small integral membrane protein 3 - GO:0016020//membrane - - gi|148677883|gb|EDL09830.1|/2.13192e-64/RIKEN cDNA 2010002N04 [Mus musculus] 74097 792 5.966666667 8.876666667 0.573092841 Up 0.600220016 Pop7 "processing of precursor 7, ribonuclease P family, (S. cerevisiae)" K14527|1|9e-63|242|mmu:74097|ribonuclease P/MRP protein subunit RPP20 [EC:3.1.26.5] GO:0043231//intracellular membrane-bounded organelle GO:0004549//tRNA-specific ribonuclease activity;GO:0097159//organic cyclic compound binding GO:0006399//tRNA metabolic process gi|13899215|ref|NP_083029.1|/7.05868e-62/ribonuclease P protein subunit p20 [Mus musculus] 15166 3195 17.88666667 13.13333333 -0.445651425 Down 0.600210613 Hcn2 "hyperpolarization-activated, cyclic nucleotide-gated K+ 2" K04955|1|0.0|1266|mmu:15166|hyperpolarization activated cyclic nucleotide-gated potassium channel 2 GO:0044297//cell body;GO:0030425//dendrite;GO:0005887//integral component of plasma membrane GO:0005267//potassium channel activity;GO:0019904//protein domain specific binding;GO:0030551//cyclic nucleotide binding GO:0042221//response to chemical;GO:0003012//muscle system process;GO:0007267//cell-cell signaling;GO:0007417//central nervous system development;GO:0008016//regulation of heart contraction;GO:0034220//ion transmembrane transport;GO:0044767//single-organism developmental process;GO:0009719;GO:0006873//cellular ion homeostasis;GO:0006814//sodium ion transport gi|6680189|ref|NP_032252.1|/0/potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [Mus musculus] 20193 615 1273.266667 1003.54 -0.34343648 Down 0.599984956 S100a1 S100 calcium binding protein A1 K17274|1|6e-14|79.3|ola:101155699|calpactin-1 light chain GO:0032991//macromolecular complex;GO:0031672//A band;GO:0031674//I band;GO:0042995//cell projection;GO:0005783//endoplasmic reticulum GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0019899//enzyme binding GO:0006366//transcription from RNA polymerase II promoter;GO:0044057;GO:0007165//signal transduction;GO:1901021//positive regulation of calcium ion transmembrane transporter activity gi|426331674|ref|XP_004026803.1|/2.41947e-43/PREDICTED: protein S100-A1 isoform 2 [Gorilla gorilla gorilla] 209268 2681.64 10.5 7.26 -0.532347875 Down 0.599956749 Igsf1 "immunoglobulin superfamily, member 1" K06512|1|3e-45|186|myb:102259054|leukocyte immunoglobulin-like receptor GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity "GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication" gi|29244558|ref|NP_808583.1|/1.29881e-139/immunoglobulin superfamily member 1 isoform short precursor [Mus musculus] 192657 3660 7.38 4.816666667 -0.615585729 Down 0.599787506 Ell2 elongation factor RNA polymerase II 2 K15183|1|0.0|1127|mmu:192657|RNA polymerase II elongation factor ELL - - - gi|116256447|ref|NP_620403.2|/0/RNA polymerase II elongation factor ELL2 [Mus musculus] 278725 1371.58 3.476666667 1.78 -0.965827511 Down 0.599787506 E130310I04Rik RIKEN cDNA E130310I04 gene K00907|1|9e-21|105|mmu:107589|myosin-light-chain kinase [EC:2.7.11.18] - - - - 100529075 70 2.94 1.4 -1.070389328 Down 0.599731092 Snord100 "small nucleolar RNA, C/D box 100" - - - - - 100039672 743 21.02 15.56333333 -0.433611581 Down 0.599693482 Msmp "microseminoprotein, prostate associated" - - - - gi|150010554|ref|NP_001092784.1|/2.87653e-75/prostate-associated microseminoprotein precursor [Mus musculus] 229600 447 9.376666667 13.16 0.489012437 Up 0.599467825 BC028528 cDNA sequence BC028528 - - - - gi|158518442|ref|NP_705733.2|/2.06965e-48/uncharacterized protein C1orf54 homolog precursor [Mus musculus] 13688 1786 30.56 23.12666667 -0.402087203 Down 0.599166949 Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 K18644|1|3e-58|228|mmu:13688|eukaryotic translation initiation factor 4E binding protein 2 - "GO:0008135//translation factor activity, RNA binding;GO:0031369//translation initiation factor binding" GO:0006413//translational initiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0019935//cyclic-nucleotide-mediated signaling gi|6753742|ref|NP_034254.1|/2.84165e-57/eukaryotic translation initiation factor 4E-binding protein 2 [Mus musculus] 100316693 100 0.75 0.01 -6.22881869 Down 0.598960096 Mir1938 microRNA 1938 - - - - - 27762 4313 5.956666667 3.703333333 -0.685680818 Down 0.598913084 Vwa7 von Willebrand factor A domain containing 7 K17341|1|6e-35|152|mze:101481170|hemicentin - - - gi|20147795|ref|NP_613048.1|/0/von Willebrand factor A domain-containing protein 7 precursor [Mus musculus] 54123 1818.8 32.68 42.63333333 0.383573875 Up 0.598480575 Irf7 interferon regulatory factor 7 K09447|1|0.0|803|mmu:54123|interferon regulatory factor 7 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding" GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0006366//transcription from RNA polymerase II promoter;GO:0019724//B cell mediated immunity;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0043543;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0006366//transcription from RNA polymerase II promoter;GO:0019724//B cell mediated immunity;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006464//cellular protein modification process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0006366//transcription from RNA polymerase II promoter;GO:0019724//B cell mediated immunity;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006464//cellular protein modification process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway gi|8567364|ref|NP_058546.1|/0/interferon regulatory factor 7 isoform 1 [Mus musculus] 18984 2527 41.42333333 53.62 0.372327568 Up 0.598442965 Por P450 (cytochrome) oxidoreductase K00327|1|0.0|1309|mmu:18984|NADPH-ferrihemoprotein reductase [EC:1.6.2.4] - - - gi|6679421|ref|NP_032924.1|/0/NADPH--cytochrome P450 reductase [Mus musculus] 216198 2400 60.13666667 77.25666667 0.36141453 Up 0.598348941 Tcp11l2 t-complex 11 (mouse) like 2 - - - - "gi|148689458|gb|EDL21405.1|/0/t-complex 11 (mouse) like 2, isoform CRA_a, partial [Mus musculus]" 21372 2302 7.986666667 5.296666667 -0.592508783 Down 0.598330137 Tbl1x transducin (beta)-like 1 X-linked K04508|1|0.0|1024|bta:100849399|transducin (beta)-like 1 GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0000975//regulatory region DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0048545//response to steroid hormone;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0050954//sensory perception of mechanical stimulus;GO:0030154//cell differentiation "gi|148697254|gb|EDL29201.1|/0/transducin (beta)-like 1 X-linked, isoform CRA_a, partial [Mus musculus]" 19228 2245.27 4.193333333 6.576666667 0.649259034 Up 0.598170296 Pth1r parathyroid hormone 1 receptor K04585|1|0.0|1130|mmu:19228|parathyroid hormone receptor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0043234//protein complex;GO:0005903//brush border;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0043234//protein complex;GO:0005903//brush border;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0043234//protein complex;GO:0005903//brush border;GO:0044459 GO:0005515//protein binding;GO:0004930//G-protein coupled receptor activity;GO:0042277//peptide binding;GO:0005515//protein binding;GO:0004930//G-protein coupled receptor activity;GO:0042277//peptide binding;GO:0005515//protein binding;GO:0004930//G-protein coupled receptor activity;GO:0042277//peptide binding GO:0001649//osteoblast differentiation;GO:0010676;GO:0008283//cell proliferation;GO:0021700//developmental maturation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0001894//tissue homeostasis;GO:0001649//osteoblast differentiation;GO:0010676;GO:0008283//cell proliferation;GO:0021700//developmental maturation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0001894//tissue homeostasis;GO:0001649//osteoblast differentiation;GO:0010676;GO:0008283//cell proliferation;GO:0021700//developmental maturation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0001894//tissue homeostasis "gi|149018420|gb|EDL77061.1|/0/parathyroid hormone receptor 1, isoform CRA_a [Rattus norvegicus]" 20973 1524 105.7766667 134.44 0.34594103 Up 0.597907029 Syngr2 synaptogyrin 2 K17783|1|2e-40|169|shr:100917660|mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2];K04403|2|2e-27|126|gfr:102037151|TAK1-binding protein 1 GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic component of membrane - GO:0006886//intracellular protein transport gi|7106429|ref|NP_033330.1|/3.39249e-109/synaptogyrin-2 [Mus musculus] 380928 6123 73.44333333 57.29666667 -0.358180329 Down 0.597295874 Lmo7 LIM domain only 7 K06084|1|0.0|2389|mmu:380928|F-box protein 20 GO:0005911//cell-cell junction;GO:0044459 GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding GO:0007155//cell adhesion gi|157311641|ref|NP_963287.2|/0/LIM domain only protein 7 [Mus musculus] 69672 1554 16.88666667 22.6 0.420438196 Up 0.597286472 Txndc15 thioredoxin domain containing 15 K09584|1|7e-07|58.2|aqu:100638395|protein disulfide-isomerase A6 [EC:5.3.4.1];K09582|2|6e-06|55.1|spu:586525|protein disulfide-isomerase A4 [EC:5.3.4.1];K13984|3|9e-06|54.3|lcm:102352509|thioredoxin domain-containing protein 5 GO:0031224//intrinsic component of membrane - GO:0019725//cellular homeostasis gi|148709278|gb|EDL41224.1|/0/RIKEN cDNA 2310047H23 [Mus musculus] 73644 1039 16.93333333 22.64 0.419007962 Up 0.597286472 2210039B01Rik RIKEN cDNA 2210039B01 gene - - - - - 30939 762.82 96.24333333 123.06 0.354603382 Up 0.596947986 Pttg1 pituitary tumor-transforming gene 1 K06635|1|1e-94|349|mmu:30939|securin GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004866//endopeptidase inhibitor activity;GO:0043021//ribonucleoprotein complex binding;GO:0019904//protein domain specific binding;GO:0004866//endopeptidase inhibitor activity;GO:0043021//ribonucleoprotein complex binding;GO:0019904//protein domain specific binding GO:0006996//organelle organization;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0000087//mitotic M phase;GO:0007127//meiosis I;GO:0010466//negative regulation of peptidase activity;GO:0008283//cell proliferation;GO:0006996//organelle organization;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0000087//mitotic M phase;GO:0007127//meiosis I;GO:0010466//negative regulation of peptidase activity;GO:0008283//cell proliferation gi|197085603|ref|NP_001124526.1|/1.62938e-110/securin isoform 1 [Mus musculus] 12876 2183 94.37 120.6166667 0.354029063 Up 0.596769341 Cpe carboxypeptidase E K01294|1|0.0|837|mmu:12876|carboxypeptidase E [EC:3.4.17.10] GO:0043005//neuron projection;GO:0030133//transport vesicle;GO:0030141//secretory granule;GO:0043025//neuronal cell body;GO:0044425;GO:0044421 GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0008235//metalloexopeptidase activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0051093//negative regulation of developmental process;GO:0006518//peptide metabolic process;GO:0003208//cardiac ventricle morphogenesis;GO:0036211//protein modification process;GO:0016486//peptide hormone processing gi|22203763|ref|NP_038522.2|/0/carboxypeptidase E preproprotein [Mus musculus] 233016 865 11.27 15.53 0.462570314 Up 0.596496672 Blvrb biliverdin reductase B (flavin reductase (NADPH)) K05901|1|4e-107|389|mmu:233016|biliverdin reductase / flavin reductase [EC:1.3.1.24 1.5.1.30] GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0031981//nuclear lumen "GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor" GO:0044710;GO:0006787;GO:0044710;GO:0006787 gi|21450325|ref|NP_659172.1|/3.23649e-106/flavin reductase (NADPH) isoform 1 [Mus musculus] 14964 1736 253.0933333 320.8766667 0.342349378 Up 0.59644966 H2-D1 "histocompatibility 2, D region locus 1" "K06751|1|0.0|733|mmu:14964|major histocompatibility complex, class I" GO:0031224//intrinsic component of membrane;GO:0042611;GO:0009986//cell surface GO:0005515//protein binding GO:0002484;GO:0002664//regulation of T cell tolerance induction;GO:0009581;GO:0001817//regulation of cytokine production "gi|133778955|ref|NP_034510.3|/0/H-2 class I histocompatibility antigen, D-B alpha chain precursor [Mus musculus]" 15528 788 89.42333333 114.2366667 0.353302559 Up 0.596092369 Hspe1 heat shock protein 1 (chaperonin 10) K04078|1|4e-42|173|mmu:15528|chaperonin GroES GO:0044429 GO:0032550;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0006915//apoptotic process;GO:0035966//response to topologically incorrect protein "gi|513020951|ref|XP_004871757.1|/6.16236e-42/PREDICTED: 10 kDa heat shock protein, mitochondrial isoform X2 [Heterocephalus glaber]" 14681 4178.63 7.57 4.98 -0.604147558 Down 0.596054759 Gnao1 "guanine nucleotide binding protein, alpha O" K04534|1|0.0|774|ocu:100342283|guanine nucleotide-binding protein G(o) subunit alpha - - - "gi|148679159|gb|EDL11106.1|/0/guanine nucleotide binding protein, alpha o, isoform CRA_a, partial [Mus musculus]" 73600 388 8.033333333 5.366666667 -0.581972458 Down 0.595932528 1700120C14Rik RIKEN cDNA 1700120C14 gene - - - - - 100042065 359 12.00333333 8.513333333 -0.495639074 Down 0.595838505 Gm3646 predicted gene 3646 - - - - gi|293629246|ref|NP_001170819.1|/4.2138e-25/uncharacterized protein LOC100042065 [Mus musculus] 18575 6811.84 6.636666667 4.266666667 -0.637349411 Down 0.595208545 Pde1c phosphodiesterase 1C "K13755|1|0.0|1163|mmu:18575|calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]" GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0044444//cytoplasmic part "GO:0043169//cation binding;GO:0005515//protein binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0005515//protein binding;GO:0030551//cyclic nucleotide binding;GO:0043169//cation binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0005515//protein binding;GO:0030551//cyclic nucleotide binding;GO:0043169//cation binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0005515//protein binding;GO:0030551//cyclic nucleotide binding;GO:0043169//cation binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0005515//protein binding;GO:0030551//cyclic nucleotide binding;GO:0043169//cation binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0005515//protein binding;GO:0030551//cyclic nucleotide binding;GO:0043169//cation binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0005515//protein binding;GO:0030551//cyclic nucleotide binding;GO:0043169//cation binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0005515//protein binding;GO:0030551//cyclic nucleotide binding;GO:0043169//cation binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity" GO:0010863//positive regulation of phospholipase C activity;GO:0038127//ERBB signaling pathway;GO:0038127//ERBB signaling pathway;GO:0050796//regulation of insulin secretion;GO:0010863//positive regulation of phospholipase C activity;GO:0046058//cAMP metabolic process;GO:0010038//response to metal ion;GO:0009154//purine ribonucleotide catabolic process;GO:0007606//sensory perception of chemical stimulus;GO:0050796//regulation of insulin secretion;GO:0046058//cAMP metabolic process;GO:0010038//response to metal ion;GO:0009154//purine ribonucleotide catabolic process;GO:0007606//sensory perception of chemical stimulus;GO:0038127//ERBB signaling pathway;GO:0050796//regulation of insulin secretion;GO:0010863//positive regulation of phospholipase C activity;GO:0046058//cAMP metabolic process;GO:0010038//response to metal ion;GO:0009154//purine ribonucleotide catabolic process;GO:0007606//sensory perception of chemical stimulus;GO:0050796//regulation of insulin secretion;GO:0046058//cAMP metabolic process;GO:0010038//response to metal ion;GO:0009154//purine ribonucleotide catabolic process;GO:0007606//sensory perception of chemical stimulus;GO:0050796//regulation of insulin secretion;GO:0046058//cAMP metabolic process;GO:0010038//response to metal ion;GO:0009154//purine ribonucleotide catabolic process;GO:0007606//sensory perception of chemical stimulus;GO:0050796//regulation of insulin secretion;GO:0046058//cAMP metabolic process;GO:0010038//response to metal ion;GO:0009154//purine ribonucleotide catabolic process;GO:0007606//sensory perception of chemical stimulus;GO:0038127//ERBB signaling pathway;GO:0050796//regulation of insulin secretion;GO:0010863//positive regulation of phospholipase C activity;GO:0046058//cAMP metabolic process;GO:0010038//response to metal ion;GO:0009154//purine ribonucleotide catabolic process;GO:0007606//sensory perception of chemical stimulus "gi|148672759|gb|EDL04706.1|/0/phosphodiesterase 1C, isoform CRA_e, partial [Mus musculus]" 15937 1090 18.81333333 25.04666667 0.412863128 Up 0.595133326 Ier3 immediate early response 3 - GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0006913//nucleocytoplasmic transport;GO:0051707//response to other organism;GO:0003073//regulation of systemic arterial blood pressure;GO:0031323//regulation of cellular metabolic process;GO:0006915//apoptotic process;GO:0006096//glycolytic process;GO:0006954//inflammatory response;GO:0009896;GO:0006281//DNA repair gi|19526808|ref|NP_598423.1|/1.607e-85/radiation-inducible immediate-early gene IEX-1 [Mus musculus] 67238 2237.22 29.61666667 38.60666667 0.382440721 Up 0.594945278 Fam220a "family with sequence similarity 220, member A" - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|165905597|ref|NP_080326.2|/5.4028e-149/protein FAM220A [Mus musculus] 102466213 91 6.283333333 9.19 0.548534744 Up 0.594606792 Mir6990 microRNA 6990 - - - - - 78353 545.62 4.96 7.5 0.596550475 Up 0.594108466 2500002B13Rik RIKEN cDNA 2500002B13 gene - - - - - 17187 1990.95 36.66 47.27 0.366718079 Up 0.594033247 Max Max protein K04453|1|7e-74|281|ngi:103749276|Max protein GO:0043005//neuron projection;GO:0044665//MLL1/2 complex;GO:0016604//nuclear body;GO:0043005//neuron projection;GO:0044665//MLL1/2 complex;GO:0016604//nuclear body GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0070997//neuron death;GO:0009611//response to wounding;GO:0043010//camera-type eye development;GO:0043434//response to peptide hormone;GO:0065003;GO:0033554//cellular response to stress;GO:0032870//cellular response to hormone stimulus;GO:0006351//transcription, DNA-templated;GO:0070997//neuron death;GO:0009611//response to wounding;GO:0043010//camera-type eye development;GO:0043434//response to peptide hormone;GO:0065003;GO:0033554//cellular response to stress;GO:0032870//cellular response to hormone stimulus" gi|226051848|ref|NP_001139648.1|/1.18455e-67/protein max isoform 2 [Mus musculus] 100316697 134 0.73 0.01 -6.189824559 Down 0.593741773 Mir1946a microRNA 1946a - - - - - 387248 93 0.01 0.726666667 6.183221824 Up 0.593675956 Mirlet7e microRNA let7e - - - - gi|594084771|ref|XP_006065940.1|/2.73215e-08/PREDICTED: basic salivary proline-rich protein 2-like isoform X2 [Bubalus bubalis] 212190 2966.9 1.946666667 3.653333333 0.908207524 Up 0.593619542 Ubxn10 UBX domain protein 10 - - - - gi|30520049|ref|NP_848786.1|/6.72725e-140/UBX domain-containing protein 10 [Mus musculus] 320404 5101 31.56333333 24.12333333 -0.387820302 Down 0.59353492 Itpkb "inositol 1,4,5-trisphosphate 3-kinase B" K00911|1|0.0|1673|mmu:320404|1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127] - GO:0051766//inositol trisphosphate kinase activity;GO:0032550;GO:0005515//protein binding GO:0007265//Ras protein signal transduction;GO:0045582//positive regulation of T cell differentiation;GO:0043368//positive T cell selection;GO:0033077//T cell differentiation in thymus;GO:0006796//phosphate-containing compound metabolic process gi|124487167|ref|NP_001074644.1|/0/inositol-trisphosphate 3-kinase B [Mus musculus] 75750 2124 4.05 6.343333333 0.647319248 Up 0.593187032 Slc10a6 "solute carrier family 10 (sodium/bile acid cotransporter family), member 6" "K14346|1|0.0|754|mmu:75750|solute carrier family 10 (sodium/bile acid cotransporter), member 6" GO:0031224//intrinsic component of membrane GO:0005343//organic acid:sodium symporter activity;GO:0008514//organic anion transmembrane transporter activity GO:0044763;GO:0015718//monocarboxylic acid transport;GO:0006814//sodium ion transport gi|21313062|ref|NP_083691.1|/0/solute carrier family 10 member 6 [Mus musculus] 71973 1956 35.09 45.33666667 0.369618375 Up 0.592848546 Rbpms2 RNA binding protein with multiple splicing 2 - - GO:0036094//small molecule binding;GO:0097159//organic cyclic compound binding - gi|31980694|ref|NP_082306.2|/1.04241e-108/RNA-binding protein with multiple splicing 2 [Mus musculus] 13549 2469.92 17.99333333 23.95666667 0.412964709 Up 0.592604084 Dyrk1b dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b K08825|1|0.0|913|pale:102896998|dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1] - - - - 26384 2300 3.186666667 5.233333333 0.715682036 Up 0.592096356 Gnpda1 glucosamine-6-phosphate deaminase 1 K02564|1|1e-167|592|mmu:26384|glucosamine-6-phosphate deaminase [EC:3.5.99.6] GO:0044424 "GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses" GO:0044237//cellular metabolic process;GO:0006041//glucosamine metabolic process;GO:0007338//single fertilization;GO:0044238//primary metabolic process gi|188219582|ref|NP_036067.2|/1.02674e-166/glucosamine-6-phosphate isomerase 1 [Mus musculus] 100038734 3389 23.35 30.51666667 0.386174835 Up 0.591927113 Gm10845 predicted gene 10845 K04676|1|2e-25|121|cge:100762264|mothers against decapentaplegic homolog 1;K09667|2|2e-22|111|ngi:103752242|protein O-GlcNAc transferase [EC:2.4.1.255] - - - gi|74180796|dbj|BAE25608.1|/5.66216e-95/unnamed protein product [Mus musculus] 69683 1855 65.41666667 83.44666667 0.351196173 Up 0.591466396 Emc10 ER membrane protein complex subunit 10 - GO:0030176//integral component of endoplasmic reticulum membrane - - gi|226342951|ref|NP_932108.2|/4.10208e-115/ER membrane protein complex subunit 10 precursor [Mus musculus] 76392 574 10.54666667 14.52 0.461254354 Up 0.591193727 Slfn5os "schlafen 5, opposite strand" - - - - - 235323 4220 29.66333333 22.71 -0.38535302 Down 0.59049795 Usp28 ubiquitin specific peptidase 28 K11849|1|0.0|2046|mmu:235323|ubiquitin carboxyl-terminal hydrolase 25/28 [EC:3.4.19.12] GO:0032991//macromolecular complex;GO:0031981//nuclear lumen GO:0016790//thiolester hydrolase activity;GO:0019783//ubiquitin-like protein-specific protease activity GO:0009411//response to UV;GO:0006259//DNA metabolic process;GO:0019941//modification-dependent protein catabolic process;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0070646//protein modification by small protein removal gi|46852151|ref|NP_780691.2|/0/ubiquitin carboxyl-terminal hydrolase 28 [Mus musculus] 232237 6023 12.64666667 9.053333333 -0.482236199 Down 0.590488548 Fgd5 "FYVE, RhoGEF and PH domain containing 5" "K05724|1|0.0|2632|mmu:232237|FYVE, RhoGEF and PH domain containing 5/6" - - - - 18217 1547 3.746666667 5.936666667 0.664045481 Up 0.589557712 Ntsr2 neurotensin receptor 2 K04212|1|0.0|738|mmu:18217|neurotensin receptor 2 GO:0031224//intrinsic component of membrane GO:0008188//neuropeptide receptor activity GO:0007267//cell-cell signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006873//cellular ion homeostasis "gi|148666060|gb|EDK98476.1|/0/neurotensin receptor 2, isoform CRA_a [Mus musculus]" 75599 3902 18.19666667 13.55333333 -0.425026482 Down 0.589266238 Pcdh1 protocadherin 1 K16498|1|0.0|1855|mmu:75599|protocadherin delta 1 - - - - 20525 2573 10.27666667 14.14333333 0.460749789 Up 0.589068788 Slc2a1 "solute carrier family 2 (facilitated glucose transporter), member 1" "K07299|1|0.0|900|xla:100036813|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1" GO:0030054//cell junction;GO:0016021//integral component of membrane;GO:0044459;GO:0045120//pronucleus;GO:0048770 GO:0005402//cation:sugar symporter activity;GO:0005355//glucose transmembrane transporter activity;GO:0051183//vitamin transporter activity;GO:0019899//enzyme binding GO:0009267//cellular response to starvation;GO:0015711//organic anion transport;GO:0015758//glucose transport gi|147898512|ref|NP_001090573.1|/0/glucose transporter 14 [Xenopus laevis] 72281 2767 5.113333333 3.113333333 -0.715804028 Down 0.588730302 Sh2d4a SH2 domain containing 4A K17577|1|0.0|801|mmu:72281|SH2 domain-containing protein 4A GO:0031981//nuclear lumen GO:0019899//enzyme binding GO:0010921//regulation of phosphatase activity gi|206597474|ref|NP_082458.1|/0/SH2 domain-containing protein 4A [Mus musculus] 102465637 65 6.86 4.49 -0.611493131 Down 0.588278988 Mir7052 microRNA 7052 - - - - - 320869 518 12.36333333 8.866666667 -0.479604022 Down 0.58825078 Spata33 spermatogenesis associated 33 K02449|1|9e-11|68.2|cfa:489655|cyclin-dependent kinase 10 [EC:2.7.11.22] - - - gi|124301188|ref|NP_796253.2|/5.88457e-53/spermatogenesis-associated protein 33 [Mus musculus] 13166 2282 2.1 0.826666667 -1.345011708 Down 0.588137952 Dbh dopamine beta hydroxylase K00503|1|0.0|1237|mmu:13166|dopamine beta-monooxygenase [EC:1.14.17.1] GO:0030133//transport vesicle;GO:0034774//secretory granule lumen;GO:0044297//cell body;GO:0031224//intrinsic component of membrane;GO:0030667//secretory granule membrane;GO:0033267 "GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen" GO:0014075//response to amine;GO:0048771//tissue remodeling;GO:0001659//temperature homeostasis;GO:0033555//multicellular organismal response to stress;GO:0060746//parental behavior;GO:0033500//carbohydrate homeostasis;GO:0042415//norepinephrine metabolic process;GO:0007612//learning;GO:0030534//adult behavior;GO:0008283//cell proliferation;GO:0007632//visual behavior;GO:0042417//dopamine metabolic process;GO:0006915//apoptotic process;GO:0019229//regulation of vasoconstriction;GO:0002252 gi|110815861|ref|NP_620392.2|/0/dopamine beta-hydroxylase [Mus musculus] 110880 6598 3.983333333 6.216666667 0.642165012 Up 0.587442175 Scn4a "sodium channel, voltage-gated, type IV, alpha" K04837|1|0.0|3362|mmu:110880|voltage-gated sodium channel type IV alpha GO:0005887//integral component of plasma membrane GO:0005272//sodium channel activity GO:0034220//ion transmembrane transport;GO:0006814//sodium ion transport gi|134948032|ref|NP_573462.2|/0/sodium channel protein type 4 subunit alpha [Mus musculus] 211228 1273 2.003333333 3.683333333 0.878609474 Up 0.58726353 Lrrc25 leucine rich repeat containing 25 - GO:0031224//intrinsic component of membrane - - gi|23346481|ref|NP_694714.1|/4.0092e-150/leucine-rich repeat-containing protein 25 precursor [Mus musculus] 20014 2716 37.89666667 48.48 0.355318742 Up 0.587244725 Rpn2 ribophorin II K12667|1|0.0|1152|mmu:20014|oligosaccharyltransferase complex subunit delta (ribophorin II) GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane GO:0004576//oligosaccharyl transferase activity;GO:0043021//ribonucleoprotein complex binding GO:0044767//single-organism developmental process;GO:0042221//response to chemical;GO:0006487//protein N-linked glycosylation gi|34996495|ref|NP_062616.2|/0/dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 precursor [Mus musculus] 237560 1428 285.69 227.3366667 -0.329620146 Down 0.586878032 Lrrc10 leucine rich repeat containing 10 K16175|1|2e-15|86.7|smm:Smp_104030.3|protein scribble GO:0043292//contractile fiber;GO:0043231//intracellular membrane-bounded organelle - - gi|74209124|dbj|BAE24955.1|/1.99013e-132/unnamed protein product [Mus musculus] 106821 1354 9.926666667 13.67 0.46163199 Up 0.586191658 Oard1 O-acyl-ADP-ribose deacylase 1 - - GO:0016787//hydrolase activity;GO:0001882//nucleoside binding;GO:0016787//hydrolase activity;GO:0001882//nucleoside binding;GO:0016787//hydrolase activity;GO:0001882//nucleoside binding GO:0009116//nucleoside metabolic process;GO:0009116//nucleoside metabolic process;GO:0009116//nucleoside metabolic process gi|110625732|ref|NP_997102.2|/2.18377e-81/O-acetyl-ADP-ribose deacetylase 1 [Mus musculus] 27047 1751 4.933333333 7.373333333 0.57975421 Up 0.585994208 Omd osteomodulin K08124|1|0.0|832|mmu:27047|osteomodulin GO:0031012//extracellular matrix - GO:0030278//regulation of ossification;GO:0022610 "gi|148709139|gb|EDL41085.1|/0/osteomodulin, isoform CRA_b, partial [Mus musculus]" 214505 1234 7.936666667 11.17333333 0.493454528 Up 0.585533491 Gnptg "N-acetylglucosamine-1-phosphotransferase, gamma subunit" "K10087|1|0.0|638|mmu:214505|N-acetylglucosamine-1-phosphate transferase, gamma subunit" GO:0043231//intracellular membrane-bounded organelle "GO:0005515//protein binding;GO:0016780//phosphotransferase activity, for other substituted phosphate groups" GO:0006491//N-glycan processing gi|49457855|ref|NP_766117.2|/0/N-acetylglucosamine-1-phosphotransferase subunit gamma precursor [Mus musculus] 433456 1231 9.166666667 6.353333333 -0.528883499 Down 0.58525142 4631405J19Rik RIKEN cDNA 4631405J19 gene - - - - gi|71682457|gb|AAI00299.1|/3.0385e-30/4631405J19Rik protein [Mus musculus] 59095 1804 15.83 21.06333333 0.41207251 Up 0.584894129 Fxyd6 FXYD domain-containing ion transport regulator 6 K13363|1|5e-35|151|cge:100770777|FXYD domain-containing ion transport regulator 6 GO:0031224//intrinsic component of membrane - GO:0044765//single-organism transport gi|148693701|gb|EDL25648.1|/1.51993e-74/FXYD domain-containing ion transport regulator 6 [Mus musculus] 11702 3206 45.84333333 58.4 0.349256421 Up 0.58465907 Amd1 S-adenosylmethionine decarboxylase 1 K01611|1|1e-180|636|mmu:11702|S-adenosylmethionine decarboxylase [EC:4.1.1.50] - - - - 69961 839 15.93 21.13 0.4075465 Up 0.584546241 Rpp25l ribonuclease P/MRP 25 subunit-like K14525|1|3e-70|267|mmu:69961|ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5] GO:0043231//intracellular membrane-bounded organelle GO:0097159//organic cyclic compound binding - gi|568927366|ref|XP_006538311.1|/1.99289e-89/PREDICTED: ribonuclease P protein subunit p25-like protein isoform X1 [Mus musculus] 338417 451 21.08333333 15.89333333 -0.407681244 Down 0.584395803 Scgb1c1 "secretoglobin, family 1C, member 1" - - - - gi|153791540|ref|NP_001093212.1|/6.46234e-26/secretoglobin family 1C member 1 precursor [Mus musculus] 259300 3058 90.73 71.88333333 -0.335922349 Down 0.584264169 Ehd2 EH-domain containing 2 K12469|1|0.0|1051|mmu:259300|EH domain-containing protein 2 GO:0010008//endosome membrane GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0046872//metal ion binding GO:0007599//hemostasis;GO:0030036//actin cytoskeleton organization;GO:0016192//vesicle-mediated transport;GO:0009154//purine ribonucleotide catabolic process gi|55742711|ref|NP_694708.2|/0/EH domain-containing protein 2 [Mus musculus] 14873 1192 195.2966667 155.6133333 -0.327701646 Down 0.584179548 Gsto1 glutathione S-transferase omega 1 K00799|1|1e-138|494|mmu:14873|glutathione S-transferase [EC:2.5.1.18] - - - - 213393 1316.32 152.9 192.5966667 0.332994328 Up 0.584179548 8430408G22Rik RIKEN cDNA 8430408G22 gene - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|22122425|ref|NP_666092.1|/6.54902e-111/protein DEPP [Mus musculus] 193385 4713.57 1.916666667 3.55 0.889219569 Up 0.584000903 Fam65b "family with sequence similarity 65, member B" - - GO:0005506//iron ion binding;GO:0003824//catalytic activity;GO:0005506//iron ion binding;GO:0003824//catalytic activity - gi|28972195|dbj|BAC65551.1|/0/mKIAA0386 protein [Mus musculus] 21838 1753 11.66333333 8.336666667 -0.484437607 Down 0.583775245 Thy1 "thymus cell antigen 1, theta" K06514|1|2e-72|276|mmu:21838|Thy-1 cell surface antigen GO:0009986//cell surface;GO:0046658//anchored component of plasma membrane;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0035091//phosphatidylinositol binding;GO:0005102//receptor binding;GO:0019900//kinase binding GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0006915//apoptotic process;GO:0006996//organelle organization;GO:0001933//negative regulation of protein phosphorylation;GO:0016477//cell migration;GO:0007409//axonogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0002274;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0042462//eye photoreceptor cell development;GO:0008285//negative regulation of cell proliferation;GO:0050852//T cell receptor signaling pathway;GO:0007155//cell adhesion;GO:0007044//cell-substrate junction assembly;GO:0042110//T cell activation gi|6678347|ref|NP_033408.1|/1.51386e-71/thy-1 membrane glycoprotein preproprotein [Mus musculus] 100526525 96 0.01 0.69 6.108524457 Up 0.582947836 Mir3092 microRNA 3092 - - - - - 100529074 105 0.01 0.686666667 6.101538026 Up 0.582891421 Snora33 "small nucleolar RNA, H/ACA box 33" - - - - - 19171 1270 42.82666667 54.58666667 0.35003921 Up 0.582863214 Psmb10 "proteasome (prosome, macropain) subunit, beta type 10" K02733|1|7e-152|539|mmu:19171|20S proteasome subunit beta 10 [EC:3.4.25.1] GO:0031981//nuclear lumen;GO:0000502//proteasome complex;GO:0044444//cytoplasmic part GO:0004175//endopeptidase activity "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0032989;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0006955//immune response;GO:0006915//apoptotic process;GO:0051320;GO:0016070//RNA metabolic process;GO:0042110//T cell activation;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|247300942|ref|NP_038668.2|/6.16314e-151/proteasome subunit beta type-10 precursor [Mus musculus] 13480 2303 1.766666667 3.343333333 0.920257341 Up 0.582844409 Dpm1 dolichol-phosphate (beta-D) mannosyltransferase 1 K00721|1|3e-138|495|mmu:13480|dolichol-phosphate mannosyltransferase [EC:2.4.1.83] - - - - 12228 1295.73 10.92333333 7.77 -0.491426668 Down 0.582599947 Btg3 B cell translocation gene 3 K14443|1|2e-132|474|mmu:12228|protein Tob/BTG GO:0044424;GO:0044424 - GO:0006950//response to stress;GO:0000278//mitotic cell cycle;GO:0008283//cell proliferation;GO:0006950//response to stress;GO:0000278//mitotic cell cycle;GO:0008283//cell proliferation gi|6753208|ref|NP_033900.1|/1.34377e-131/protein BTG3 [Mus musculus] 212933 3540 6.31 4.1 -0.622016095 Down 0.581857159 Pm20d1 peptidase M20 domain containing 1 K13049|1|0.0|996|mmu:212933|carboxypeptidase PM20D1 [EC:3.4.17.-] - GO:0016787//hydrolase activity;GO:0043169//cation binding GO:0019538//protein metabolic process gi|227908835|ref|NP_835180.2|/0/probable carboxypeptidase PM20D1 precursor [Mus musculus] 217830 3229 26.44 34.09 0.366626423 Up 0.581810147 9030617O03Rik RIKEN cDNA 9030617O03 gene - GO:0043231//intracellular membrane-bounded organelle - - "gi|148686944|gb|EDL18891.1|/0/RIKEN cDNA 9030617O03, isoform CRA_a, partial [Mus musculus]" 66968 1981.96 114.3766667 143.9666667 0.33194205 Up 0.581509271 Plin5 perilipin 5 K20255|1|0.0|892|mmu:66968|perilipin-5 - - - gi|116292164|ref|NP_001070816.1|/0/perilipin-5 [Mus musculus] 277414 2687 21.41333333 27.91666667 0.382617298 Up 0.581293016 Trp53i11 transformation related protein 53 inducible protein 11 - GO:0031224//intrinsic component of membrane - - "gi|148695671|gb|EDL27618.1|/1.06463e-93/Trp53 inducible protein 11, isoform CRA_d, partial [Mus musculus]" 12589 2957 8.266666667 11.50333333 0.476674353 Up 0.58118959 Ift81 intraflagellar transport 81 K19677|1|0.0|1311|mmu:12589|intraflagellar transport protein 81 GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle - GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|15638942|ref|NP_034009.2|/0/intraflagellar transport protein 81 homolog [Mus musculus] 116701 2561.54 8.186666667 11.43 0.481477344 Up 0.58118959 Fgfrl1 fibroblast growth factor receptor-like 1 K05094|1|2e-36|156|xtr:100196923|fibroblast growth factor receptor 3 [EC:2.7.10.1];K05095|2|4e-36|155|lcm:102345296|fibroblast growth factor receptor 4 [EC:2.7.10.1] GO:0030133//transport vesicle;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane GO:0019838//growth factor binding;GO:0005539//glycosaminoglycan binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0019838//growth factor binding;GO:0005539//glycosaminoglycan binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity GO:0060538//skeletal muscle organ development;GO:0003170//heart valve development;GO:0008283//cell proliferation;GO:0006464//cellular protein modification process;GO:0016049//cell growth;GO:0003281//ventricular septum development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0060538//skeletal muscle organ development;GO:0003170//heart valve development;GO:0008283//cell proliferation;GO:0006464//cellular protein modification process;GO:0016049//cell growth;GO:0003281//ventricular septum development;GO:0008543//fibroblast growth factor receptor signaling pathway gi|16905101|ref|NP_473412.1|/0/fibroblast growth factor receptor-like 1 isoform 1 precursor [Mus musculus] 66952 1296 2.43 4.186666667 0.784845745 Up 0.580616044 2310030G06Rik RIKEN cDNA 2310030G06 gene - - - - gi|13385350|ref|NP_080141.1|/5.49993e-78/uncharacterized protein C11orf52 homolog [Mus musculus] 319604 6610 10.66666667 7.59 -0.490937614 Down 0.580418594 Fam168a "family with sequence similarity 168, member A" - - - - gi|928165529|ref|XP_005633583.2|/6.8208e-103/PREDICTED: protein FAM168A isoform X3 [Canis lupus familiaris] 68267 2586.88 39.12333333 49.89666667 0.350914146 Up 0.580268156 Slc25a22 "solute carrier family 25 (mitochondrial carrier, glutamate), member 22" "K15107|1|9e-164|580|mmu:68267|solute carrier family 25 (mitochondrial glutamate transporter), member 18/22" GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0019866//organelle inner membrane GO:0015291//secondary active transmembrane transporter activity;GO:0005310//dicarboxylic acid transmembrane transporter activity GO:0044763;GO:0006835//dicarboxylic acid transport gi|21311845|ref|NP_080922.1|/7.82695e-163/mitochondrial glutamate carrier 1 [Mus musculus] 276829 2624 6.073333333 8.756666667 0.527893241 Up 0.580202339 Smtnl2 smoothelin-like 2 K10314|1|7e-122|441|bacu:103002192|F-box protein 39;K06115|2|6e-20|102|mze:101474420|spectrin beta - - - "gi|148680730|gb|EDL12677.1|/0/RIKEN cDNA D130058I21, isoform CRA_a, partial [Mus musculus]" 13039 3509 54.58333333 69.18333333 0.341964025 Up 0.579863853 Ctsl cathepsin L K01365|1|0.0|676|mmu:13039|cathepsin L [EC:3.4.22.15] - - - - 319594 6190 10.06666667 7.11 -0.501664584 Down 0.579816842 Hif1an "hypoxia-inducible factor 1, alpha subunit inhibitor" K18055|1|0.0|687|mmu:319594|hypoxia-inducible factor 1-alpha inhibitor (HIF hydroxylase) [EC:1.14.11.30] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0019904//protein domain specific binding;GO:0019825//oxygen binding;GO:0042802//identical protein binding;GO:0043168//anion binding;GO:0008134//transcription factor binding" GO:0007219//Notch signaling pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0045445//myoblast differentiation;GO:0018126//protein hydroxylation;GO:0044710;GO:0001570//vasculogenesis gi|70909332|ref|NP_795932.2|/0/hypoxia-inducible factor 1-alpha inhibitor [Mus musculus] 54397 1732.21 38.13333333 48.61 0.350200488 Up 0.579365527 Ppt2 palmitoyl-protein thioesterase 2 K01074|1|1e-165|585|mmu:54397|palmitoyl-protein thioesterase [EC:3.1.2.22] GO:0000323//lytic vacuole;GO:0000323//lytic vacuole GO:0016790//thiolester hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0016790//thiolester hydrolase activity GO:0036211//protein modification process;GO:0036211//protein modification process;GO:0036211//protein modification process;GO:0036211//protein modification process;GO:0036211//protein modification process gi|795466039|ref|XP_011890013.1|/3.32851e-169/PREDICTED: lysosomal thioesterase PPT2 isoform X8 [Cercocebus atys] 654820 2391.26 5.676666667 8.256666667 0.540515434 Up 0.579111663 G530011O06Rik RIKEN cDNA G530011O06 gene - - - - - 78373 1285 2.37 4.086666667 0.786037514 Up 0.578923615 Nudt17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 K03023|1|2e-41|172|fpg:101919330|DNA-directed RNA polymerase III subunit RPC3 - GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0003824//catalytic activity - gi|242397440|ref|NP_084370.1|/4.63644e-146/nucleoside diphosphate-linked moiety X motif 17 isoform 1 [Mus musculus] 17190 2672 23.85666667 18.26666667 -0.385179086 Down 0.578716763 Mbd1 methyl-CpG binding domain protein 1 K11589|1|0.0|1051|mmu:17190|methyl-CpG-binding domain protein 1 GO:0016604//nuclear body;GO:0000785//chromatin;GO:0034399//nuclear periphery GO:0003676//nucleic acid binding;GO:0046872//metal ion binding "GO:0006305;GO:0006351//transcription, DNA-templated" gi|157817372|ref|NP_038622.2|/0/methyl-CpG-binding domain protein 1 [Mus musculus] 102466210 74 2.606666667 1.25 -1.060278012 Down 0.578190229 Mir6955 microRNA 6955 - - - - - 15267 556 50.24666667 63.62 0.34045248 Up 0.578171424 Hist2h2aa1 "histone cluster 2, H2aa1" K11251|1|6e-55|215|ssc:100511884|histone H2A - - - - 11544 1583 28.74666667 36.96333333 0.362700187 Up 0.578067998 Adprh ADP-ribosylarginine hydrolase K01245|1|0.0|758|mmu:11544|ADP-ribosylarginine hydrolase [EC:3.2.2.19] - "GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds" GO:0006464//cellular protein modification process gi|6680658|ref|NP_031440.1|/0/ADP-ribosylarginine hydrolase [Mus musculus] 69253 910 50.31666667 63.59666667 0.3379148 Up 0.578049193 Hspb2 heat shock protein 2 K09543|1|1e-83|311|chx:102175970|heat shock protein beta-2 GO:0043231//intracellular membrane-bounded organelle;GO:0044424 - GO:0061061//muscle structure development;GO:0006950//response to stress gi|926709358|ref|XP_005689675.2|/9.42652e-83/PREDICTED: heat shock protein beta-2 [Capra hircus] 194401 9367.87 16.81333333 12.54 -0.423068427 Down 0.577926962 Mical3 "microtubule associated monooxygenase, calponin and LIM domain containing 3" K19947|1|0.0|3037|rno:362427|protein-methionine sulfoxide oxidase MICAL [EC:1.14.13.-] GO:0043232 GO:0046914//transition metal ion binding;GO:0016491//oxidoreductase activity;GO:0008092//cytoskeletal protein binding GO:0016192//vesicle-mediated transport;GO:0044710 gi|74209994|dbj|BAE21292.1|/0/unnamed protein product [Mus musculus] 69745 939 12.42666667 16.68333333 0.424968209 Up 0.577785927 Pold4 "polymerase (DNA-directed), delta 4" K03505|1|2e-30|134|mmu:69745|DNA polymerase delta subunit 4 GO:0031981//nuclear lumen;GO:0042575 GO:0005488//binding;GO:0034061//DNA polymerase activity GO:0006289//nucleotide-excision repair;GO:0000723//telomere maintenance;GO:0006261//DNA-dependent DNA replication;GO:0051320;GO:0001935//endothelial cell proliferation gi|664703981|ref|XP_008531929.1|/3.34014e-53/PREDICTED: DNA polymerase delta subunit 4 [Equus przewalskii] 83673 476 4.65 6.933333333 0.576318406 Up 0.577738915 Snhg1 small nucleolar RNA host gene 1 - - - - - 244091 2976 103.11 82.06333333 -0.329374596 Down 0.577428636 Fsd2 fibronectin type III and SPRY domain containing 2 "K08285|1|2e-39|167|ecb:100049999|midline 1 [EC:2.3.2.27];K20479|2|7e-38|162|ggo:101146369|WASP homolog-associated protein with actin, membranes and microtubules;K10647|3|2e-36|157|shr:100932405|midline 2 [EC:2.3.2.27]" - - - gi|116063550|ref|NP_766492.2|/0/fibronectin type III and SPRY domain-containing protein 2 [Mus musculus] 18810 14887.7 45.53 35.69333333 -0.351162821 Down 0.577297003 Plec plectin K10388|1|0.0|3881|mmu:18810|plectin GO:0016323//basolateral plasma membrane;GO:0030055//cell-substrate junction;GO:0043232;GO:0044444//cytoplasmic part;GO:0016323//basolateral plasma membrane;GO:0030055//cell-substrate junction;GO:0043232;GO:0044444//cytoplasmic part;GO:0016323//basolateral plasma membrane;GO:0030055//cell-substrate junction;GO:0043232;GO:0044444//cytoplasmic part;GO:0016323//basolateral plasma membrane;GO:0030055//cell-substrate junction;GO:0043232;GO:0044444//cytoplasmic part;GO:0016323//basolateral plasma membrane;GO:0030055//cell-substrate junction;GO:0043232;GO:0044444//cytoplasmic part;GO:0016323//basolateral plasma membrane;GO:0030055//cell-substrate junction;GO:0043232;GO:0044444//cytoplasmic part;GO:0016323//basolateral plasma membrane;GO:0030055//cell-substrate junction;GO:0043232;GO:0044444//cytoplasmic part;GO:0016323//basolateral plasma membrane;GO:0030055//cell-substrate junction;GO:0043232;GO:0044444//cytoplasmic part;GO:0016323//basolateral plasma membrane;GO:0030055//cell-substrate junction;GO:0043232;GO:0044444//cytoplasmic part;GO:0016323//basolateral plasma membrane;GO:0030055//cell-substrate junction;GO:0043232;GO:0044444//cytoplasmic part;GO:0016323//basolateral plasma membrane;GO:0030055//cell-substrate junction;GO:0043232;GO:0044444//cytoplasmic part;GO:0016323//basolateral plasma membrane;GO:0030055//cell-substrate junction;GO:0043232;GO:0044444//cytoplasmic part;GO:0016323//basolateral plasma membrane;GO:0030055//cell-substrate junction;GO:0043232;GO:0044444//cytoplasmic part;GO:0016323//basolateral plasma membrane;GO:0030055//cell-substrate junction;GO:0043232;GO:0044444//cytoplasmic part;GO:0016323//basolateral plasma membrane;GO:0030055//cell-substrate junction;GO:0043232;GO:0044444//cytoplasmic part GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity GO:0031667//response to nutrient levels;GO:0007044//cell-substrate junction assembly;GO:0031667//response to nutrient levels;GO:0007044//cell-substrate junction assembly;GO:0031667//response to nutrient levels;GO:0007044//cell-substrate junction assembly;GO:0031667//response to nutrient levels;GO:0007044//cell-substrate junction assembly;GO:0031667//response to nutrient levels;GO:0007044//cell-substrate junction assembly;GO:0031667//response to nutrient levels;GO:0007044//cell-substrate junction assembly;GO:0031667//response to nutrient levels;GO:0007044//cell-substrate junction assembly;GO:0031667//response to nutrient levels;GO:0007044//cell-substrate junction assembly;GO:0031667//response to nutrient levels;GO:0007044//cell-substrate junction assembly;GO:0031667//response to nutrient levels;GO:0007044//cell-substrate junction assembly;GO:0031667//response to nutrient levels;GO:0007044//cell-substrate junction assembly;GO:0031667//response to nutrient levels;GO:0007044//cell-substrate junction assembly;GO:0031667//response to nutrient levels;GO:0007044//cell-substrate junction assembly;GO:0031667//response to nutrient levels;GO:0007044//cell-substrate junction assembly;GO:0031667//response to nutrient levels;GO:0007044//cell-substrate junction assembly "gi|148697587|gb|EDL29534.1|/0/plectin 1, isoform CRA_b [Mus musculus]" 735277 109 0.666666667 0.01 -6.058893689 Down 0.577165369 Mir697 microRNA 697 - - - - - 100316676 98 0.01 0.666666667 6.058893689 Up 0.577165369 Mir1195 microRNA 1195 - - - - - 71242 721 4.483333333 2.683333333 -0.740545484 Down 0.577080748 Spata24 spermatogenesis associated 24 - GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0003676//nucleic acid binding;GO:0042802//identical protein binding "GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated" gi|56961629|ref|NP_082009.3|/1.69862e-85/spermatogenesis-associated protein 24 isoform 1 [Mus musculus] 545622 6369 9.676666667 6.82 -0.504738427 Down 0.576629433 Ptpn3 "protein tyrosine phosphatase, non-receptor type 3" K18027|1|0.0|1827|mmu:545622|tyrosine-protein phosphatase non-receptor type 3 [EC:3.1.3.48] GO:0044459;GO:0043232 GO:0004672//protein kinase activity;GO:0019899//enzyme binding;GO:0004721//phosphoprotein phosphatase activity GO:0000278//mitotic cell cycle;GO:0006470//protein dephosphorylation;GO:0006509//membrane protein ectodomain proteolysis gi|568927055|ref|XP_006538160.1|/0/PREDICTED: tyrosine-protein phosphatase non-receptor type 3 isoform X2 [Mus musculus] 67388 1065 45.01666667 57.02333333 0.341093141 Up 0.575877242 1110008F13Rik RIKEN cDNA 1110008F13 gene K12870|1|9e-17|90.1|tsp:Tsp_02139|pre-mRNA-splicing factor ISY1 GO:0043231//intracellular membrane-bounded organelle - - gi|593716110|ref|XP_007104508.1|/2.23592e-68/PREDICTED: uncharacterized protein C20orf24 homolog isoform X1 [Physeter catodon] 83997 5388.01 22.22 16.92333333 -0.392845057 Down 0.575802023 Slmap sarcolemma associated protein K10251|1|4e-29|134|cmy:102938030|17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330];K10421|2|8e-22|109|mze:101463599|CAP-Gly domain-containing linker protein 1 - - - gi|37360470|dbj|BAC98213.1|/0/mKIAA1601 protein [Mus musculus] 66350 1562.23 45.22333333 57.14 0.337433702 Up 0.57563278 Pla2g12a "phospholipase A2, group XIIA" K01047|1|8e-69|263|mmu:66350|secretory phospholipase A2 [EC:3.1.1.4] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0004623//phospholipase A2 activity;GO:0046872//metal ion binding;GO:0004623//phospholipase A2 activity;GO:0046872//metal ion binding;GO:0003824//catalytic activity;GO:0046872//metal ion binding;GO:0004623//phospholipase A2 activity GO:0046488//phosphatidylinositol metabolic process;GO:0046470//phosphatidylcholine metabolic process;GO:0006658//phosphatidylserine metabolic process;GO:0046473//phosphatidic acid metabolic process;GO:0046471//phosphatidylglycerol metabolic process;GO:0046488//phosphatidylinositol metabolic process;GO:0046470//phosphatidylcholine metabolic process;GO:0006658//phosphatidylserine metabolic process;GO:0046473//phosphatidic acid metabolic process;GO:0046471//phosphatidylglycerol metabolic process;GO:0006629//lipid metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0046488//phosphatidylinositol metabolic process;GO:0046470//phosphatidylcholine metabolic process;GO:0006658//phosphatidylserine metabolic process;GO:0046473//phosphatidic acid metabolic process;GO:0046471//phosphatidylglycerol metabolic process "gi|148680280|gb|EDL12227.1|/2.97325e-64/phospholipase A2, group XIIA, isoform CRA_b, partial [Mus musculus]" 12721 1686 4.53 6.766666667 0.578934271 Up 0.575557561 Coro1a "coronin, actin binding protein 1A" K13882|1|0.0|944|mmu:12721|coronin-1A - - - gi|6753492|ref|NP_034028.1|/0/coronin-1A isoform 1 [Mus musculus] 50874 1241 11.4 8.23 -0.470069489 Down 0.575096845 Tmod4 tropomodulin 4 K10370|1|8e-180|632|mmu:50874|tropomodulin GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding GO:0003012//muscle system process gi|7710104|ref|NP_057921.1|/6.77851e-179/tropomodulin-4 [Mus musculus] 12925 460 87.28333333 69.35666667 -0.331671636 Down 0.574984016 Crip1 cysteine-rich protein 1 (intestinal) K09851|1|3e-24|112|nve:NEMVE_v1g108380|Ras association domain-containing protein 2/4 GO:0044424 GO:0046914//transition metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0033218//amide binding GO:0012501//programmed cell death;GO:0010038//response to metal ion;GO:0010224//response to UV-B;GO:0046677//response to antibiotic;GO:0044767//single-organism developmental process;GO:0002376//immune system process;GO:0003006//developmental process involved in reproduction;GO:0010467//gene expression "gi|148686610|gb|EDL18557.1|/1.67606e-50/cysteine-rich protein 1 (intestinal), isoform CRA_a [Mus musculus]" 269999 1996 12.20333333 16.28 0.415825427 Up 0.574542104 Orai3 ORAI calcium release-activated calcium modulator 3 K16058|1|1e-163|579|mmu:269999|calcium release-activated calcium channel protein 3 GO:0031224//intrinsic component of membrane - - gi|38259222|ref|NP_940816.1|/9.86728e-163/protein orai-3 [Mus musculus] 60533 3653 1.873333333 3.42 0.868388695 Up 0.574382263 Cd274 CD274 antigen K06745|1|4e-166|588|mmu:60533|programmed cell death 1 ligand 1 GO:0031224//intrinsic component of membrane;GO:0031988//membrane-bounded vesicle;GO:0009986//cell surface GO:0005488//binding GO:0050715//positive regulation of cytokine secretion;GO:0042098//T cell proliferation;GO:0007165//signal transduction;GO:0031294//lymphocyte costimulation gi|11230798|ref|NP_068693.1|/3.30483e-165/programmed cell death 1 ligand 1 precursor [Mus musculus] 723902 108 0.01 0.66 6.044394119 Up 0.574372861 Mir7-1 microRNA 7-1 - - - - - 102466634 114 0.66 0.01 -6.044394119 Down 0.574372861 Mir6363 microRNA 6363 - - - - - 13830 2816 66.60333333 83.64333333 0.328656175 Up 0.574090789 Stom stomatin K17286|1|5e-141|504|mmu:13830|erythrocyte band 7 integral membrane protein GO:0043232;GO:0031988//membrane-bounded vesicle;GO:0016021//integral component of membrane - GO:0051259//protein oligomerization gi|7710018|ref|NP_038543.1|/4.6664e-140/erythrocyte band 7 integral membrane protein [Mus musculus] 104103 781.5 2.566666667 4.303333333 0.74555865 Up 0.574043778 Airn antisense Igf2r RNA - - - - "gi|148670101|gb|EDL02048.1|/1.21634e-24/mCG142215, isoform CRA_c [Mus musculus]" 319190 2667 2.626666667 4.386666667 0.739891954 Up 0.574034375 Hist2h2be "histone cluster 2, H2be" K11252|1|6e-43|178|mmu:319190|histone H2B GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0006952//defense response;GO:0034728//nucleosome organization "gi|148706929|gb|EDL38876.1|/1.07129e-53/histone 2, H2be [Mus musculus]" 237615 6615 21.63333333 16.49666667 -0.391081436 Down 0.57381812 Ankrd52 ankyrin repeat domain 52 K15504|1|0.0|2152|mmu:237615|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C - - - gi|27370168|ref|NP_766378.1|/0/serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C [Mus musculus] 76192 1967 32.5 41.38666667 0.348726339 Up 0.573808718 Abhd12 abhydrolase domain containing 12 K13704|1|0.0|783|mmu:76192|abhydrolase domain-containing protein 12 [EC:3.1.1.23] GO:0008328//ionotropic glutamate receptor complex GO:0016298//lipase activity - "gi|12805339|gb|AAH02138.1|/0/Abhd12 protein, partial [Mus musculus]" 102465900 131 5.593333333 3.596666667 -0.637047851 Down 0.573291587 Mir8112 microRNA 8112 - - - - - 12262 1063 62.82333333 79.06666667 0.331769111 Up 0.57326338 C1qc "complement component 1, q subcomponent, C chain" K03988|1|7e-105|382|mmu:12262|complement C1q subcomponent subunit C - - - - 208643 5444.94 145.0233333 116.1566667 -0.320213081 Down 0.573094137 Eif4g1 "eukaryotic translation initiation factor 4, gamma 1" K03260|1|0.0|2588|mmu:208643|translation initiation factor 4G GO:0043234//protein complex;GO:0044424;GO:0043234//protein complex;GO:0044424 "GO:0008135//translation factor activity, RNA binding;GO:0031369//translation initiation factor binding;GO:0008135//translation factor activity, RNA binding;GO:0031369//translation initiation factor binding" GO:0006413//translational initiation;GO:0006413//translational initiation gi|751130496|ref|NP_001291361.1|/0/eukaryotic translation initiation factor 4 gamma 1 isoform c [Mus musculus] 73713 6607 28 21.73666667 -0.365296108 Down 0.572680432 Rbm20 RNA binding motif protein 20 K13213|1|6e-25|120|cmk:103177265|matrin 3 - - - - 677884 7371 3.056666667 1.593333333 -0.939911116 Down 0.572586408 Pakap paralemmin A kinase anchor protein K16519|1|0.0|1887|mmu:677884|A-kinase anchor protein 2 - - - - 67149 2571 10.61 14.34333333 0.434955683 Up 0.572417165 Nkain1 Na+/K+ transporting ATPase interacting 1 - GO:0031224//intrinsic component of membrane - - gi|165377302|ref|NP_080274.2|/1.55194e-118/sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 precursor [Mus musculus] 100504518 5553 39.88333333 31.36333333 -0.346707092 Down 0.572106886 3425401B19Rik RIKEN cDNA 3425401B19 gene - - - - gi|304361750|ref|NP_001182026.1|/0/uncharacterized protein C10orf71 homolog [Mus musculus] 231148 3635.43 8.566666667 11.75666667 0.456673216 Up 0.571956448 Ablim2 actin-binding LIM protein 2 K07520|1|0.0|1087|mmu:231148|actin-binding LIM protein GO:0005856//cytoskeleton;GO:0031981//nuclear lumen;GO:0043292//contractile fiber;GO:0043292//contractile fiber;GO:0043292//contractile fiber;GO:0043292//contractile fiber;GO:0005856//cytoskeleton;GO:0031981//nuclear lumen;GO:0043292//contractile fiber GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding GO:0006996//organelle organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006996//organelle organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006996//organelle organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006996//organelle organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006996//organelle organization;GO:0006366//transcription from RNA polymerase II promoter gi|295148104|ref|NP_001171170.1|/0/actin-binding LIM protein 2 isoform 5 [Mus musculus] 13489 1549 1.116666667 2.393333333 1.099822748 Up 0.571881229 Drd2 dopamine receptor D2 K04145|1|0.0|846|mmu:13489|dopamine receptor D2 GO:0043025//neuronal cell body;GO:0033267;GO:0044327//dendritic spine head;GO:0031514//motile cilium;GO:0030141//secretory granule;GO:0044459;GO:0016021//integral component of membrane;GO:0008021//synaptic vesicle GO:0004952//dopamine neurotransmitter receptor activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0035254//glutamate receptor binding "GO:0007067//mitotic nuclear division;GO:0030252//growth hormone secretion;GO:0035249//synaptic transmission, glutamatergic;GO:0014821;GO:0035264//multicellular organism growth;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0009611//response to wounding;GO:0006814//sodium ion transport;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0001964//startle response;GO:0050796//regulation of insulin secretion;GO:0003073//regulation of systemic arterial blood pressure;GO:0043270//positive regulation of ion transport;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007638//mechanosensory behavior;GO:0007212//dopamine receptor signaling pathway;GO:1901020//negative regulation of calcium ion transmembrane transporter activity;GO:0007632//visual behavior;GO:0002090//regulation of receptor internalization;GO:0007606//sensory perception of chemical stimulus;GO:0006650//glycerophospholipid metabolic process;GO:0097305//response to alcohol;GO:0045860//positive regulation of protein kinase activity;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0021830//interneuron migration from the subpallium to the cortex;GO:0009306//protein secretion;GO:0014072//response to isoquinoline alkaloid;GO:0007613//memory;GO:0032225//regulation of synaptic transmission, dopaminergic;GO:0051283//negative regulation of sequestering of calcium ion;GO:0048168//regulation of neuronal synaptic plasticity;GO:0008016//regulation of heart contraction;GO:0001763//morphogenesis of a branching structure;GO:0015909//long-chain fatty acid transport;GO:0040012//regulation of locomotion;GO:0014075//response to amine;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0006584//catecholamine metabolic process;GO:0006813//potassium ion transport;GO:0007405//neuroblast proliferation;GO:0010921//regulation of phosphatase activity;GO:0007612//learning;GO:0050807//regulation of synapse organization;GO:0021983//pituitary gland development;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0035813//regulation of renal sodium excretion;GO:0010038//response to metal ion;GO:0035809;GO:0014046;GO:0048871//multicellular organismal homeostasis;GO:0008344//adult locomotory behavior;GO:0042754//negative regulation of circadian rhythm" gi|672061753|ref|XP_008764412.1|/0/PREDICTED: D(2) dopamine receptor isoform X1 [Rattus norvegicus] 110796 5814 8.096666667 5.616666667 -0.527613899 Down 0.571815412 Tshz1 teashirt zinc finger family member 1 K09236|1|0.0|1962|mmu:110796|teashirt GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0003002//regionalization;GO:0042471//ear morphogenesis;GO:0010467//gene expression gi|60360598|dbj|BAD90534.1|/0/mKIAA4206 protein [Mus musculus] 241431 11969 23.52666667 18.05666667 -0.381765339 Down 0.571589755 Xirp2 xin actin-binding repeat containing 2 "K19947|1|8e-11|74.3|aqu:105311991|protein-methionine sulfoxide oxidase MICAL [EC:1.14.13.-];K20478|2|5e-10|71.6|dwi:Dwil_GK22102|golgin subfamily B member 1;K12046|5|9e-10|70.9|sko:100372087|troponin T, fast skeletal muscle" GO:0031674//I band;GO:0031674//I band GO:0046914//transition metal ion binding;GO:0042805//actinin binding;GO:0046914//transition metal ion binding;GO:0042805//actinin binding GO:0007010//cytoskeleton organization;GO:0034330;GO:0003007//heart morphogenesis;GO:0003231//cardiac ventricle development;GO:0007010//cytoskeleton organization;GO:0034330;GO:0003007//heart morphogenesis;GO:0003231//cardiac ventricle development gi|66841385|ref|NP_001019789.1|/0/xin actin-binding repeat-containing protein 2 isoform 1 [Mus musculus] 102566 2530.85 18.28666667 23.74333333 0.376730368 Up 0.571495731 Ano10 anoctamin 10 K19327|1|0.0|1250|mmu:102566|anoctamin-10 GO:0044464;GO:0034702//ion channel complex;GO:0034702//ion channel complex;GO:0044464 GO:0005254//chloride channel activity;GO:0005254//chloride channel activity - gi|30794236|ref|NP_598740.1|/0/anoctamin-10 isoform 1 [Mus musculus] 791347 450 0.01 0.653333333 6.029747343 Up 0.571270074 Gm10007 predicted gene 10007 K19895|1|2e-13|76.6|mmu:14585|GDNF family receptor alpha 1 GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0009986//cell surface;GO:0044421 GO:0005102//receptor binding;GO:0004896//cytokine receptor activity GO:0030030//cell projection organization;GO:0048870//cell motility;GO:0006935//chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030154//cell differentiation;GO:0008406//gonad development "gi|148669850|gb|EDL01797.1|/1.39766e-12/glial cell line derived neurotrophic factor family receptor alpha 1, isoform CRA_b, partial [Mus musculus]" 19872 111 0.01 0.65 6.022367813 Up 0.571270074 Rny1 "RNA, Y1 small cytoplasmic, Ro-associated" - - - - - 67966 1257 2.12 3.72 0.811238357 Up 0.571241867 Zcchc10 "zinc finger, CCHC domain containing 10" K19613|1|7e-09|64.3|ame:100578773|leucine-rich repeat protein SHOC2 - GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding - "gi|148701653|gb|EDL33600.1|/6.09188e-26/zinc finger, CCHC domain containing 10, isoform CRA_b [Mus musculus]" 19215 806 637.87 514.2166667 -0.310886057 Down 0.570828162 Ptgds prostaglandin D2 synthase (brain) K01830|1|1e-86|321|mmu:19215|prostaglandin-H2 D-isomerase [EC:5.3.99.2] GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0044421 GO:0016860//intramolecular oxidoreductase activity;GO:0019840//isoprenoid binding GO:0006693//prostaglandin metabolic process;GO:0042749//regulation of circadian sleep/wake cycle;GO:0031960//response to corticosteroid;GO:0051234//establishment of localization "gi|148676301|gb|EDL08248.1|/2.11194e-101/prostaglandin D2 synthase (brain), isoform CRA_a, partial [Mus musculus]" 497652 1425 11.38333333 15.24333333 0.421255341 Up 0.570414457 Acd adrenocortical dysplasia K11114|1|0.0|741|mmu:497652|adrenocortical dysplasia protein GO:0000782//telomere cap complex;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0019899//enzyme binding GO:0048731//system development;GO:0035108//limb morphogenesis;GO:0015031//protein transport;GO:0022607//cellular component assembly;GO:0034502//protein localization to chromosome;GO:0003002//regionalization;GO:0016233//telomere capping;GO:0051347//positive regulation of transferase activity;GO:0007004//telomere maintenance via telomerase;GO:0043388//positive regulation of DNA binding gi|60593059|ref|NP_001012656.1|/0/adrenocortical dysplasia protein [Mus musculus] 78376 953 3.723333333 2.13 -0.80574135 Down 0.570254617 Sapcd1 suppressor APC domain containing 1 - - - - gi|254939597|ref|NP_076382.3|/3.09069e-71/suppressor APC domain-containing protein 1 [Mus musculus] 68173 1777 12.30333333 9.023333333 -0.44731685 Down 0.570160593 Ppifos "peptidylprolyl isomerase F, opposite strand" K09565|1|6e-13|78.6|mmu:105675|peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8] GO:0005743//mitochondrial inner membrane GO:0008144//drug binding;GO:0033218//amide binding;GO:0016859//cis-trans isomerase activity GO:0010155//regulation of proton transport;GO:0043462//regulation of ATPase activity;GO:0032410//negative regulation of transporter activity;GO:0034614//cellular response to reactive oxygen species;GO:0010823//negative regulation of mitochondrion organization;GO:0070265//necrotic cell death;GO:0051592//response to calcium ion;GO:0044267//cellular protein metabolic process;GO:0046685//response to arsenic-containing substance;GO:0010822//positive regulation of mitochondrion organization;GO:0097193//intrinsic apoptotic signaling pathway;GO:0002082//regulation of oxidative phosphorylation;GO:0006839//mitochondrial transport gi|12860006|dbj|BAB31835.1|/4.24829e-52/unnamed protein product [Mus musculus] 68777 974.2 18.44333333 13.98 -0.399735062 Down 0.569981947 Tmem53 transmembrane protein 53 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|551410787|ref|NP_001272743.1|/3.27397e-131/transmembrane protein 53 isoform c [Mus musculus] 12266 5139 65.33 51.98666667 -0.329603986 Down 0.5697939 C3 complement component 3 K03990|1|0.0|3243|mmu:12266|complement component 3 GO:0031988//membrane-bounded vesicle;GO:0044421 GO:0061135;GO:0031714//C5a anaphylatoxin chemotactic receptor binding GO:0001525//angiogenesis;GO:0006909//phagocytosis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007599//hemostasis;GO:0010827//regulation of glucose transport;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0043627//response to estrogen;GO:0001905;GO:0019432//triglyceride biosynthetic process;GO:0001819//positive regulation of cytokine production;GO:0045927//positive regulation of growth;GO:0001932//regulation of protein phosphorylation;GO:0010038//response to metal ion;GO:0032787//monocarboxylic acid metabolic process;GO:0031960//response to corticosteroid;GO:0010883//regulation of lipid storage;GO:0043410//positive regulation of MAPK cascade;GO:0006952//defense response;GO:0010466//negative regulation of peptidase activity "gi|148706296|gb|EDL38243.1|/0/complement component 3, isoform CRA_c, partial [Mus musculus]" 238803 2788 2.403333333 1.13 -1.088713986 Down 0.5697939 Zfp366 zinc finger protein 366 K09228|1|4e-75|285|mze:106675525|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0035258//steroid hormone receptor binding GO:0048545//response to steroid hormone;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter gi|51921301|ref|NP_001004149.1|/0/zinc finger protein 366 [Mus musculus] 232157 1562 4.386666667 2.643333333 -0.730766718 Down 0.569775095 Mob1a MOB kinase activator 1A K06685|1|9e-124|446|lve:103079604|MOB kinase activator 1 GO:0044444//cytoplasmic part "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0043169//cation binding" GO:0035556//intracellular signal transduction "gi|148666661|gb|EDK99077.1|/4.37116e-144/MOB1, Mps One Binder kinase activator-like 1B (yeast), isoform CRA_b, partial [Mus musculus]" 13038 1583 0.343333333 1.34 1.964551164 Up 0.568994697 Ctsk cathepsin K K01371|1|0.0|686|mmu:13038|cathepsin K [EC:3.4.22.38] - - - - 100113364 116 0.643333333 0.01 -6.007494537 Down 0.568430554 Snora15 "small nucleolar RNA, H/ACA box 15" - - - - - 12683 1164 35.41666667 44.81333333 0.339499607 Up 0.568308323 Cidea "cell death-inducing DNA fragmentation factor, alpha subunit-like effector A" "K02310|1|7e-08|60.8|sko:100375419|DNA fragmentation factor, 45 kD, alpha subunit;K02311|5|8e-06|53.9|bfo:BRAFLDRAFT_229336|DNA fragmentation factor, 40 kD, beta subunit [EC:3.-.-.-]" GO:0043231//intracellular membrane-bounded organelle;GO:0031967;GO:0044444//cytoplasmic part GO:0042802//identical protein binding "GO:0006351//transcription, DNA-templated;GO:0000737//DNA catabolic process, endonucleolytic;GO:0010884//positive regulation of lipid storage;GO:0050663//cytokine secretion;GO:0006974//cellular response to DNA damage stimulus;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001818//negative regulation of cytokine production;GO:0006915//apoptotic process;GO:0009895;GO:0080184//response to phenylpropanoid;GO:0048871//multicellular organismal homeostasis" gi|162287227|ref|NP_031728.2|/4.6262e-110/cell death activator CIDE-A [Mus musculus] 69675 6632 11.96 8.76 -0.449214615 Down 0.56774418 Pxdn peroxidasin K19511|1|0.0|2919|mmu:69675|peroxidase [EC:1.11.1.7] - - - - 73750 4037.43 19.39333333 25.10333333 0.372318149 Up 0.567668961 Whrn whirlin K16175|1|7e-17|92.8|bfo:BRAFLDRAFT_198676|protein scribble;K11828|5|2e-16|91.7|amj:102560362|discs large protein 4 GO:0030425//dendrite;GO:0044297//cell body;GO:0015629//actin cytoskeleton;GO:0005578//proteinaceous extracellular matrix;GO:0005902//microvillus;GO:0002141//stereocilia ankle link;GO:0031513//nonmotile primary cilium;GO:0030425//dendrite;GO:0044297//cell body;GO:0015629//actin cytoskeleton;GO:0005578//proteinaceous extracellular matrix;GO:0005902//microvillus;GO:0002141//stereocilia ankle link;GO:0031513//nonmotile primary cilium;GO:0030425//dendrite;GO:0044297//cell body;GO:0015629//actin cytoskeleton;GO:0005578//proteinaceous extracellular matrix;GO:0005902//microvillus;GO:0002141//stereocilia ankle link;GO:0031513//nonmotile primary cilium;GO:0030425//dendrite;GO:0044297//cell body;GO:0015629//actin cytoskeleton;GO:0005578//proteinaceous extracellular matrix;GO:0005902//microvillus;GO:0002141//stereocilia ankle link;GO:0031513//nonmotile primary cilium;GO:0030425//dendrite;GO:0044297//cell body;GO:0015629//actin cytoskeleton;GO:0005578//proteinaceous extracellular matrix;GO:0005902//microvillus;GO:0002141//stereocilia ankle link;GO:0031513//nonmotile primary cilium GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0001894//tissue homeostasis;GO:0050954//sensory perception of mechanical stimulus;GO:0030030//cell projection organization;GO:0001894//tissue homeostasis;GO:0050954//sensory perception of mechanical stimulus;GO:0030030//cell projection organization;GO:0001894//tissue homeostasis;GO:0050954//sensory perception of mechanical stimulus;GO:0030030//cell projection organization;GO:0001894//tissue homeostasis;GO:0050954//sensory perception of mechanical stimulus;GO:0030030//cell projection organization;GO:0050954//sensory perception of mechanical stimulus;GO:0030030//cell projection organization gi|57012338|ref|NP_001008791.1|/0/whirlin isoform 2 [Mus musculus] 98365 1152 2.08 3.643333333 0.808675467 Up 0.567518523 Slamf9 SLAM family member 9 K06570|1|1e-30|136|umr:103672034|lymphocyte antigen 9 - - - gi|176866315|ref|NP_083888.3|/1.61831e-107/SLAM family member 9 precursor [Mus musculus] 109672 749 76.01666667 94.59666667 0.315473583 Up 0.567490316 Cyb5a cytochrome b5 type A (microsomal) K00387|1|1e-12|75.5|bmor:101743629|sulfite oxidase [EC:1.8.3.1];K10226|2|4e-12|73.9|aam:106490046|acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046906//tetrapyrrole binding;GO:0043169//cation binding;GO:0005515//protein binding GO:0051234//establishment of localization;GO:0032787//monocarboxylic acid metabolic process;GO:0010038//response to metal ion;GO:0006091//generation of precursor metabolites and energy gi|526252990|ref|NP_001268328.1|/8.23608e-78/cytochrome b5-like [Mesocricetus auratus] 16372 2646 2.51 4.19 0.73926288 Up 0.567424499 Irx2 Iroquois related homeobox 2 (Drosophila) K19383|1|4e-09|66.6|spu:575445|homeobox protein TGIF1;K19553|3|1e-07|61.2|crg:105320634|homeobox protein TGIF2 - - - - 76681 1553 3.19 5.046666667 0.661774375 Up 0.567001392 Trim12a tripartite motif-containing 12A K10648|1|2e-150|534|mmu:319236|tripartite motif-containing protein 5 [EC:2.3.2.27] GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002831;GO:0051259//protein oligomerization;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0000165//MAPK cascade;GO:0002758//innate immune response-activating signal transduction gi|63101703|gb|AAH94899.1|/2.21102e-168/Trim12 protein [Mus musculus] 78321 2319 248.2266667 199.8966667 -0.312403696 Down 0.566982587 Ankrd23 ankyrin repeat domain 23 K15503|1|5e-22|108|cmy:102935647|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B GO:0030017//sarcomere;GO:0043231//intracellular membrane-bounded organelle;GO:0044291//cell-cell contact zone;GO:0030017//sarcomere;GO:0043231//intracellular membrane-bounded organelle;GO:0044291//cell-cell contact zone GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0032787//monocarboxylic acid metabolic process;GO:0032787//monocarboxylic acid metabolic process gi|27883850|ref|NP_705722.2|/9.12448e-147/ankyrin repeat domain-containing protein 23 isoform 1 [Mus musculus] 12259 1082 70.47333333 88.22 0.324028306 Up 0.566879161 C1qa "complement component 1, q subcomponent, alpha polypeptide" K03986|1|3e-111|404|mmu:12259|complement C1q subcomponent subunit A GO:0005578//proteinaceous extracellular matrix - GO:0006952//defense response;GO:0002455//humoral immune response mediated by circulating immunoglobulin gi|74196890|dbj|BAE35005.1|/2.42848e-110/unnamed protein product [Mus musculus] 230815 4715 12.14666667 16.15333333 0.411271446 Up 0.566437248 Man1c1 "mannosidase, alpha, class 1C, member 1" "K01230|1|0.0|1176|mmu:230815|mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]" GO:0031228//intrinsic component of Golgi membrane GO:0046872//metal ion binding;GO:0015924//mannosyl-oligosaccharide mannosidase activity GO:0006029//proteoglycan metabolic process;GO:0019318//hexose metabolic process;GO:0006487//protein N-linked glycosylation "gi|46402229|ref|NP_997120.1|/0/mannosyl-oligosaccharide 1,2-alpha-mannosidase IC [Mus musculus]" 170757 4106 27.83333333 21.62333333 -0.364224759 Down 0.566117567 Adgrl4 adhesion G protein-coupled receptor L4 K04595|1|0.0|1452|mmu:170757|latrophilin and seven transmembrane domain containing 1 GO:0044421;GO:0012506//vesicle membrane;GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding;GO:0005515//protein binding GO:0007186//G-protein coupled receptor signaling pathway gi|170650603|ref|NP_573485.2|/0/adhesion G protein-coupled receptor L4 precursor [Mus musculus] 57783 2766.68 27.77666667 21.58 -0.364178615 Down 0.566004739 Tnip1 TNFAIP3 interacting protein 1 K20478|1|1e-08|65.1|ccw:104697611|golgin subfamily B member 1;K18669|2|1e-08|64.7|cin:100176948|dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1];K09291|3|1e-08|64.7|apla:101790179|nucleoprotein TPR;K10352|4|2e-08|64.3|lcm:102364995|myosin heavy chain GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0019901//protein kinase binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0043130//ubiquitin binding;GO:0019901//protein kinase binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0043130//ubiquitin binding;GO:0019901//protein kinase binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0043130//ubiquitin binding;GO:0019901//protein kinase binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0043130//ubiquitin binding;GO:0019901//protein kinase binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0043130//ubiquitin binding GO:0006366//transcription from RNA polymerase II promoter;GO:0016337//single organismal cell-cell adhesion;GO:0009100//glycoprotein metabolic process;GO:0043409//negative regulation of MAPK cascade;GO:0006954//inflammatory response;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006366//transcription from RNA polymerase II promoter;GO:0016337//single organismal cell-cell adhesion;GO:0009100//glycoprotein metabolic process;GO:0043409//negative regulation of MAPK cascade;GO:0006954//inflammatory response;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006366//transcription from RNA polymerase II promoter;GO:0016337//single organismal cell-cell adhesion;GO:0009100//glycoprotein metabolic process;GO:0043409//negative regulation of MAPK cascade;GO:0006954//inflammatory response;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006366//transcription from RNA polymerase II promoter;GO:0016337//single organismal cell-cell adhesion;GO:0009100//glycoprotein metabolic process;GO:0043409//negative regulation of MAPK cascade;GO:0006954//inflammatory response;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006366//transcription from RNA polymerase II promoter;GO:0016337//single organismal cell-cell adhesion;GO:0009100//glycoprotein metabolic process;GO:0043409//negative regulation of MAPK cascade;GO:0006954//inflammatory response;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling gi|407027874|ref|NP_001258385.1|/0/TNFAIP3-interacting protein 1 isoform 3 [Mus musculus] 60425 1481 193.96 156.2033333 -0.312333918 Down 0.565280755 Doc2g "double C2, gamma" K19918|1|0.0|720|mmu:60425|double C2-like domain-containing protein gamma GO:0030136//clathrin-coated vesicle - GO:0051234//establishment of localization gi|40254529|ref|NP_068563.2|/0/double C2-like domain-containing protein gamma [Mus musculus] 667034 1223 3.096666667 1.66 -0.899532854 Down 0.565243146 Pnp2 purine-nucleoside phosphorylase 2 K03783|1|9e-176|618|mmu:667034|purine-nucleoside phosphorylase [EC:2.4.2.1] GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0002054;GO:0043168//anion binding;GO:0016763//transferase activity, transferring pentosyl groups" GO:0006915//apoptotic process;GO:0006281//DNA repair;GO:0046102;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0044283//small molecule biosynthetic process;GO:0009151;GO:0042453;GO:0045582//positive regulation of T cell differentiation;GO:0008617//guanosine metabolic process;GO:0010212//response to ionizing radiation;GO:0009435//NAD biosynthetic process;GO:0042221//response to chemical;GO:0030183//B cell differentiation;GO:0032623//interleukin-2 production;GO:0009152//purine ribonucleotide biosynthetic process;GO:0046094;GO:0042098//T cell proliferation;GO:0046495//nicotinamide riboside metabolic process gi|183074535|ref|NP_001116843.1|/7.58263e-175/purine-nucleoside phosphorylase 2 [Mus musculus] 171210 2215 61.94 77.42 0.321834925 Up 0.564575576 Acot2 acyl-CoA thioesterase 2 K01068|1|0.0|840|mmu:171210|acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2] GO:0044429 GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0005515//protein binding GO:0000038//very long-chain fatty acid metabolic process;GO:0009719;GO:0042221//response to chemical;GO:0009991//response to extracellular stimulus;GO:0006732;GO:0006950//response to stress "gi|238624114|ref|NP_598949.3|/0/acyl-coenzyme A thioesterase 2, mitochondrial precursor [Mus musculus]" 19082 1680 62.68666667 78.05 0.316240015 Up 0.564453345 Prkag1 "protein kinase, AMP-activated, gamma 1 non-catalytic subunit" "K07200|1|0.0|650|mmu:19082|5'-AMP-activated protein kinase, regulatory gamma subunit" GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0032550;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0019887//protein kinase regulator activity;GO:0019900//kinase binding GO:0001934//positive regulation of protein phosphorylation;GO:0010467//gene expression;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0051259//protein oligomerization;GO:0006096//glycolytic process;GO:0022402//cell cycle process;GO:0048232//male gamete generation;GO:0019217//regulation of fatty acid metabolic process gi|124107596|ref|NP_058061.2|/0/5'-AMP-activated protein kinase subunit gamma-1 [Mus musculus] 56788 3576 4.02 6.05 0.589739641 Up 0.564453345 Scube2 "signal peptide, CUB domain, EGF-like 2" K06825|1|1e-86|324|sko:100374579|fibrillin 1 GO:0019898//extrinsic component of membrane GO:0046872//metal ion binding;GO:0005515//protein binding - "gi|283046678|ref|NP_064436.2|/0/signal peptide, CUB and EGF-like domain-containing protein 2 precursor [Mus musculus]" 114301 2414 39.86666667 31.42666667 -0.343193726 Down 0.564387529 Palmd palmdelphin K16519|1|0.0|1001|mmu:114301|A-kinase anchor protein 2 GO:0030425//dendrite;GO:0044424 - GO:0022604//regulation of cell morphogenesis gi|89363042|ref|NP_075734.3|/0/palmdelphin [Mus musculus] 380711 6410 20.63666667 15.86 -0.379817188 Down 0.56384219 Rap1gap2 RAP1 GTPase activating protein 2 K17708|1|0.0|1383|mmu:380711|RAP1 GTPase activating protein 2 - - - - 12036 1770.3 59.43666667 74.23 0.32064916 Up 0.563795178 Bcat2 "branched chain aminotransferase 2, mitochondrial" K00826|1|0.0|801|mmu:12036|branched-chain amino acid aminotransferase [EC:2.6.1.42] - - - - 330814 8202 6.126666667 4.09 -0.583001518 Down 0.563776374 Adgrl1 adhesion G protein-coupled receptor L1 K04592|1|0.0|2529|mmu:330814|latrophilin 1 GO:0031224//intrinsic component of membrane;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding GO:0007417//central nervous system development;GO:0016337//single organismal cell-cell adhesion;GO:0051094//positive regulation of developmental process;GO:0006887//exocytosis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0019722//calcium-mediated signaling gi|913517852|ref|XP_013210535.1|/0/PREDICTED: latrophilin-1 isoform X2 [Microtus ochrogaster] 56332 4191 39.36666667 31.11333333 -0.339441592 Down 0.563522509 Amotl2 angiomotin-like 2 K06104|1|2e-87|327|aam:106495490|angiomotin like 1 GO:0043296//apical junction complex;GO:0005768//endosome;GO:0031982//vesicle;GO:0044459 GO:0005515//protein binding GO:0035556//intracellular signal transduction gi|568963046|ref|XP_006511835.1|/0/PREDICTED: angiomotin-like protein 2 isoform X2 [Mus musculus] 74777 3461 9.693333333 13.05333333 0.429353496 Up 0.563513107 Sepn1 "selenoprotein N, 1" K19874|1|0.0|882|mmu:74777|selenoprotein N - - - gi|111118964|ref|NP_083376.2|/0/selenoprotein N [Mus musculus] 16542 5464 51.52666667 41.04 -0.328288535 Down 0.563503705 Kdr kinase insert domain protein receptor K05098|1|0.0|2645|mmu:16542|kinase insert domain protein receptor [EC:2.7.10.1] GO:0009986//cell surface;GO:0031982//vesicle;GO:0042995//cell projection;GO:0016021//integral component of membrane;GO:0044297//cell body;GO:0005768//endosome GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0032550;GO:0019838//growth factor binding GO:0010720//positive regulation of cell development;GO:0021700//developmental maturation;GO:0001935//endothelial cell proliferation;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0030097//hemopoiesis;GO:0050918//positive chemotaxis;GO:0003158//endothelium development;GO:0008284//positive regulation of cell proliferation;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0007507//heart development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0031175//neuron projection development;GO:0042311//vasodilation;GO:0043410//positive regulation of MAPK cascade;GO:0030509//BMP signaling pathway;GO:0048875//chemical homeostasis within a tissue;GO:0010594//regulation of endothelial cell migration;GO:0008585//female gonad development;GO:0019722//calcium-mediated signaling;GO:0022604//regulation of cell morphogenesis;GO:0071363//cellular response to growth factor stimulus;GO:0006950//response to stress;GO:0043066//negative regulation of apoptotic process;GO:0002040//sprouting angiogenesis;GO:0001954//positive regulation of cell-matrix adhesion;GO:0030324//lung development;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0060562//epithelial tube morphogenesis gi|27777648|ref|NP_034742.2|/0/vascular endothelial growth factor receptor 2 precursor [Mus musculus] 72865 965 14.15 18.53333333 0.389320329 Up 0.56344729 Cxx1c CAAX box 1C - - - - gi|13386306|ref|NP_082651.1|/3.05058e-50/CAAX box 1 homolog C [Mus musculus] 18146 1522 15.70333333 20.40666667 0.377969713 Up 0.562751514 Npdc1 "neural proliferation, differentiation and control 1" "K01509|1|1e-69|266|aml:100477610|adenosinetriphosphatase [EC:3.6.1.3];K09367|2|2e-34|149|asn:102370955|POU domain transcription factor, class 5" GO:0031224//intrinsic component of membrane - - gi|31982836|ref|NP_032747.2|/2.31154e-166/neural proliferation differentiation and control protein 1 precursor [Mus musculus] 12846 2082.85 120.2733333 148.64 0.305505599 Up 0.562676295 Comt catechol-O-methyltransferase K00545|1|2e-135|485|mmu:12846|catechol O-methyltransferase [EC:2.1.1.6] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008171//O-methyltransferase activity;GO:0043169//cation binding;GO:0008171//O-methyltransferase activity;GO:0043169//cation binding;GO:0008171//O-methyltransferase activity;GO:0043169//cation binding GO:0044703;GO:0008202//steroid metabolic process;GO:0007611//learning or memory;GO:0033555//multicellular organismal response to stress;GO:0042053//regulation of dopamine metabolic process;GO:0008285//negative regulation of cell proliferation;GO:0042133//neurotransmitter metabolic process;GO:0031337;GO:0002237//response to molecule of bacterial origin;GO:0044703;GO:0008202//steroid metabolic process;GO:0007611//learning or memory;GO:0033555//multicellular organismal response to stress;GO:0042053//regulation of dopamine metabolic process;GO:0008285//negative regulation of cell proliferation;GO:0042133//neurotransmitter metabolic process;GO:0031337;GO:0002237//response to molecule of bacterial origin;GO:0044703;GO:0008202//steroid metabolic process;GO:0007611//learning or memory;GO:0033555//multicellular organismal response to stress;GO:0042053//regulation of dopamine metabolic process;GO:0008285//negative regulation of cell proliferation;GO:0042133//neurotransmitter metabolic process;GO:0031337;GO:0002237//response to molecule of bacterial origin gi|161484634|ref|NP_031770.2|/2.16623e-134/catechol O-methyltransferase [Mus musculus] 110265 1348.11 39.49666667 49.62 0.329190833 Up 0.562356614 Msra methionine sulfoxide reductase A K07304|1|7e-94|346|mmu:110265|peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor" GO:0036211//protein modification process;GO:0006950//response to stress;GO:0044767//single-organism developmental process;GO:0000096//sulfur amino acid metabolic process;GO:0036211//protein modification process;GO:0006950//response to stress;GO:0044767//single-organism developmental process;GO:0000096//sulfur amino acid metabolic process;GO:0044710;GO:0044767//single-organism developmental process;GO:0044710;GO:0044767//single-organism developmental process;GO:0044710;GO:0044767//single-organism developmental process "gi|148704100|gb|EDL36047.1|/1.98953e-119/methionine sulfoxide reductase A, isoform CRA_b, partial [Mus musculus]" 68161 705.51 20.09666667 15.44 -0.380283476 Down 0.562319004 A930005H10Rik RIKEN cDNA A930005H10 gene - - - - gi|26388259|dbj|BAC25640.1|/9.30923e-39/unnamed protein product [Mus musculus] 100526479 64 22.89333333 17.73333333 -0.368463794 Down 0.562008725 Mir3082 microRNA 3082 - - - - - 71091 1689 4.21 2.55 -0.723322986 Down 0.561999323 Cdkl1 cyclin-dependent kinase-like 1 (CDC2-related kinase) K08824|1|0.0|733|mmu:71091|cyclin-dependent kinase-like [EC:2.7.11.22] GO:0043231//intracellular membrane-bounded organelle GO:0004674//protein serine/threonine kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0044767//single-organism developmental process gi|34304105|ref|NP_899117.1|/0/cyclin-dependent kinase-like 1 [Mus musculus] 434768 1206 1.78 3.233333333 0.861145005 Up 0.561707849 Rhox8 reproductive homeobox 8 K09452|1|7e-14|80.9|dan:Dana_GF20646|homeobox protein aristaless-related;K09357|2|3e-13|79.0|cmy:102947119|paired-like homeodomain transcription factor 3;K09356|3|3e-13|79.0|mmu:18740|paired-like homeodomain transcription factor 1;K09451|4|4e-13|78.2|xtr:100493396|homeobox protein aristaless-like 4;K09329|5|7e-13|77.4|xtr:100488907|paired mesoderm homeobox protein - - - - 20148 1620.47 107.4766667 133.19 0.309462285 Up 0.561538606 Dhrs3 dehydrogenase/reductase (SDR family) member 3 K11146|1|4e-172|607|mmu:20148|short-chain dehydrogenase/reductase 3 [EC:1.1.1.300] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0008106//alcohol dehydrogenase (NADP+) activity;GO:0036094//small molecule binding;GO:0008106//alcohol dehydrogenase (NADP+) activity;GO:0036094//small molecule binding GO:0044710;GO:0044710 gi|6755380|ref|NP_035433.1|/3.76237e-157/short-chain dehydrogenase/reductase 3 isoform 1 [Mus musculus] 77446 4804 5.563333333 3.636666667 -0.613332853 Down 0.561519801 Heg1 heart development protein with EGF-like domains 1 K06794|1|9e-19|99.4|mze:101468755|neurocan core protein;K02599|2|4e-17|94.0|pale:102889752|Notch - - - - 71941 1867 23.34666667 29.81666667 0.352902399 Up 0.561284742 Cars2 cysteinyl-tRNA synthetase 2 (mitochondrial)(putative) K01883|1|0.0|1072|mmu:71941|cysteinyl-tRNA synthetase [EC:6.1.1.16] - - - gi|26332939|dbj|BAC30187.1|/0/unnamed protein product [Mus musculus] 264895 3069 29.95666667 23.49333333 -0.350625678 Down 0.561171913 Acsf2 acyl-CoA synthetase family member 2 K00666|1|0.0|1229|mmu:264895|fatty-acyl-CoA synthase [EC:6.2.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity;GO:0032550 GO:0032787//monocarboxylic acid metabolic process;GO:0044238//primary metabolic process "gi|24418933|ref|NP_722502.1|/0/acyl-CoA synthetase family member 2, mitochondrial precursor [Mus musculus]" 72203 2905 6.733333333 9.38 0.478267036 Up 0.561124901 2610507I01Rik RIKEN cDNA 2610507I01 gene - - - - "gi|148675725|gb|EDL07672.1|/1.07601e-30/mCG1044118, isoform CRA_a [Mus musculus]" 19817 332 1.49 2.853333333 0.937335965 Up 0.561096694 Rn7sk "RNA, 7SK, nuclear" K17570|1|2e-09|63.2|ssc:100624841|hydrocephalus-inducing protein;K17896|2|2e-07|56.2|umr:103660578|GATA-binding protein 5 - - - gi|432116232|gb|ELK37276.1|/3.44784e-36/hypothetical protein MDA_GLEAN10012073 [Myotis davidii] 268780 4864 3.67 5.593333333 0.607928247 Up 0.560767611 Egflam "EGF-like, fibronectin type III and laminin G domains" K06254|1|1e-93|348|bta:525795|agrin GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix GO:0097367//carbohydrate derivative binding;GO:0097367//carbohydrate derivative binding;GO:0097367//carbohydrate derivative binding GO:0043062//extracellular structure organization;GO:0010810//regulation of cell-substrate adhesion;GO:0018149//peptide cross-linking;GO:0043062//extracellular structure organization;GO:0010810//regulation of cell-substrate adhesion;GO:0018149//peptide cross-linking;GO:0043062//extracellular structure organization;GO:0010810//regulation of cell-substrate adhesion;GO:0018149//peptide cross-linking gi|575501633|ref|NP_001276427.1|/0/pikachurin isoform 3 [Mus musculus] 12608 1518 28.96666667 36.57333333 0.336398445 Up 0.560692392 Cebpb "CCAAT/enhancer binding protein (C/EBP), beta" "K10048|1|8e-92|340|mmu:12608|CCAAT/enhancer binding protein (C/EBP), beta" - - - - 104010 3586 1.386666667 2.713333333 0.968445266 Up 0.560382113 Cdh22 cadherin 22 K06812|1|0.0|1387|mmu:104010|cadherin 22 GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0007417//central nervous system development;GO:0016337//single organismal cell-cell adhesion gi|164698424|ref|NP_778153.2|/0/cadherin-22 precursor [Mus musculus] 68854 1534.79 97.79333333 120.8666667 0.305608401 Up 0.560325699 Asb11 ankyrin repeat and SOCS box-containing 11 K10333|1|1e-159|565|rno:302666|ankyrin repeat and SOCS box protein 11 - - - - 107999 1615 5.536666667 7.893333333 0.511617008 Up 0.560325699 Gtpbp6 GTP binding protein 6 (putative) K15202|1|1e-44|183|chx:102179861|general transcription factor 3C polypeptide 5 (transcription factor C subunit 1) - GO:0032550 - gi|165972313|ref|NP_660129.2|/0/putative GTP-binding protein 6 [Mus musculus] 83554 1953 6.533333333 4.43 -0.56051255 Down 0.560100041 Fstl3 follistatin-like 3 K09171|1|2e-122|442|ocu:100350712|nuclear factor I/X;K04661|2|2e-64|249|cmk:103177837|follistatin "GO:0043005//neuron projection;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0044421" GO:0032403//protein complex binding GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0009968//negative regulation of signal transduction;GO:0016337//single organismal cell-cell adhesion;GO:0008406//gonad development;GO:0010038//response to metal ion;GO:0030323//respiratory tube development;GO:0048232//male gamete generation;GO:0035270//endocrine system development;GO:0032924//activin receptor signaling pathway;GO:0030509//BMP signaling pathway gi|13878203|ref|NP_113557.1|/5.27969e-153/follistatin-related protein 3 precursor [Mus musculus] 327655 5559 24.92666667 19.42333333 -0.359899161 Down 0.559601715 Ppip5k1 diphosphoinositol pentakisphosphate kinase 1 K13024|1|0.0|2731|mmu:327655|inositol-hexakisphosphate/diphosphoinositol-pentakisphosphate 1-kinase [EC:2.7.4.24] GO:0044444//cytoplasmic part GO:0016791//phosphatase activity;GO:0000828//inositol hexakisphosphate kinase activity;GO:0032550 GO:0019751//polyol metabolic process;GO:0006796//phosphate-containing compound metabolic process gi|28972185|dbj|BAC65546.1|/0/mKIAA0377 protein [Mus musculus] 70598 4207 19.21 14.75 -0.381142565 Down 0.559244424 Filip1 filamin A interacting protein 1 K20478|1|3e-20|104|dre:557772|golgin subfamily B member 1 GO:0043232 - - gi|124486975|ref|NP_001074712.1|/0/filamin-A-interacting protein 1 [Mus musculus] 546611 1602 2.766666667 4.46 0.688894874 Up 0.559197412 Klhl33 kelch-like 33 K13957|1|0.0|1027|mmu:546611|kelch-like protein 33 - - - gi|262263393|ref|NP_001160123.1|/0/kelch-like protein 33 [Mus musculus] 97418 116 0.61 0.01 -5.930737338 Down 0.559122193 Rnu5g "RNA, U5G small nuclear" - - - - - 233073 864 35.54333333 44.56333333 0.326278163 Up 0.558774305 U2af1l4 U2 small nuclear RNA auxiliary factor 1-like 4 K12836|1|5e-103|376|ecb:100051464|splicing factor U2AF 35 kDa subunit - - - gi|667279995|ref|XP_008573907.1|/1.00018e-104/PREDICTED: splicing factor U2AF 26 kDa subunit isoform X1 [Galeopterus variegatus] 69539 1671 1.636666667 0.586666667 -1.480147596 Down 0.558727293 Trnp1 TMF1-regulated nuclear protein 1 - - - - gi|34850573|gb|AAN28928.1|/4.63477e-38/mexneurin precursor [Mus musculus] 16777 5778 19.15333333 14.72333333 -0.37949116 Down 0.558680281 Lamb1 laminin B1 "K05636|1|0.0|3679|mmu:16777|laminin, beta 1" - - - "gi|148704971|gb|EDL36918.1|/0/laminin B1 subunit 1, partial [Mus musculus]" 17758 5594.99 104.63 84.41 -0.309810738 Down 0.558642672 Map4 microtubule-associated protein 4 K10431|1|0.0|1931|mmu:17758|microtubule-associated protein 4 GO:0005819//spindle;GO:0005819//spindle;GO:0005819//spindle;GO:0005819//spindle;GO:0016020//membrane GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0000278//mitotic cell cycle;GO:0007018//microtubule-based movement;GO:0030010//establishment of cell polarity;GO:0000278//mitotic cell cycle;GO:0007018//microtubule-based movement;GO:0030010//establishment of cell polarity;GO:0000278//mitotic cell cycle;GO:0007018//microtubule-based movement;GO:0030010//establishment of cell polarity;GO:0000278//mitotic cell cycle;GO:0007018//microtubule-based movement;GO:0030010//establishment of cell polarity "gi|148677082|gb|EDL09029.1|/0/microtubule-associated protein 4, isoform CRA_b, partial [Mus musculus]" 668661 2001 7.94 10.83666667 0.448710143 Up 0.558482831 2410002F23Rik RIKEN cDNA 2410002F23 gene K10601|1|1e-05|54.7|gga:100859884|E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27] - - - gi|262072980|ref|NP_080156.2|/2.36407e-148/uncharacterized protein C19orf48 homolog [Mus musculus] 69986 902 4.223333333 2.583333333 -0.709148309 Down 0.558454624 1700025N23Rik RIKEN cDNA 1700025N23 gene - - - - - 13180 822 0.446666667 1.43 1.678744647 Up 0.558417015 Pcbd1 pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1 K01724|1|1e-54|215|mmu:13180|4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] - - - - 110558 1539 5.266666667 7.536666667 0.517036434 Up 0.558407612 H2-Q9 "histocompatibility 2, Q region locus 9" "K06751|1|3e-178|627|mmu:110558|major histocompatibility complex, class I" GO:0031224//intrinsic component of membrane;GO:0042611;GO:0009986//cell surface GO:0005515//protein binding;GO:0003823//antigen binding GO:0002484;GO:0001819//positive regulation of cytokine production;GO:0002664//regulation of T cell tolerance induction;GO:0002252;GO:0009581;GO:0002428 "gi|319803125|ref|NP_001188389.1|/2.94289e-177/H-2 class I histocompatibility antigen, Q9 alpha chain precursor [Mus musculus]" 102465627 65 1.66 3.063333333 0.883919119 Up 0.5583606 Mir7036 microRNA 7036 - - - - - 286940 9118 9.126666667 6.55 -0.478593134 Down 0.558351198 Flnb "filamin, beta" K04437|1|0.0|5196|mmu:286940|filamin - - - - 70827 6286 43.10666667 34.25 -0.331807019 Down 0.558106736 Trak2 "trafficking protein, kinesin binding 2" K15374|1|0.0|1654|mmu:70827|trafficking kinesin-binding protein 2 GO:0005768//endosome;GO:0016020//membrane GO:0005102//receptor binding GO:0044765//single-organism transport;GO:0006486//protein glycosylation;GO:0006886//intracellular protein transport;GO:0006366//transcription from RNA polymerase II promoter gi|40254203|ref|NP_765994.2|/0/trafficking kinesin-binding protein 2 [Mus musculus] 52004 911 16.57666667 21.36333333 0.365982839 Up 0.55776825 Cdk2ap2 CDK2-associated protein 2 K17868|1|5e-07|57.4|loa:LOAG_04022|diphthine methyl ester acylhydrolase [EC:3.1.1.97] - - - gi|444510168|gb|ELV09503.1|/5.46271e-43/Calcium-binding protein 2 [Tupaia chinensis] 73836 2138 9.053333333 12.20333333 0.430754294 Up 0.557542593 Slc35b2 "solute carrier family 35, member B2" "K15276|1|0.0|791|rno:501103|solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0060089;GO:0000295//adenine nucleotide transmembrane transporter activity GO:0015711//organic anion transport;GO:0007249//I-kappaB kinase/NF-kappaB signaling "gi|148691502|gb|EDL23449.1|/0/mCG18237, isoform CRA_c [Mus musculus]" 107747 3098 1.766666667 3.19 0.852526565 Up 0.557486178 Aldh1l1 "aldehyde dehydrogenase 1 family, member L1" K00289|1|0.0|1717|mmu:107747|formyltetrahydrofolate dehydrogenase [EC:1.5.1.6] GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0016741;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0005515//protein binding" GO:0009396//folic acid-containing compound biosynthetic process;GO:0009256//10-formyltetrahydrofolate metabolic process gi|27532959|ref|NP_081682.1|/0/cytosolic 10-formyltetrahydrofolate dehydrogenase [Mus musculus] 100303751 112 0.64 1.696666667 1.406559345 Up 0.557213509 Snora31 "small nucleolar RNA, H/ACA box 31" - - - - gi|344240969|gb|EGV97072.1|/8.39305e-10/hypothetical protein I79_006530 [Cricetulus griseus] 30948 2135 3.586666667 5.456666667 0.605376244 Up 0.557185302 Bin1 bridging integrator 1 K12562|1|0.0|1115|mmu:30948|amphiphysin GO:0005856//cytoskeleton;GO:0033267;GO:0030136//clathrin-coated vesicle;GO:0033267;GO:0030136//clathrin-coated vesicle GO:0046983//protein dimerization activity;GO:0019899//enzyme binding;GO:0046983//protein dimerization activity;GO:0019899//enzyme binding GO:0043087//regulation of GTPase activity;GO:0006897//endocytosis;GO:0030154//cell differentiation;GO:0043087//regulation of GTPase activity;GO:0006897//endocytosis;GO:0030154//cell differentiation gi|6753050|ref|NP_033798.1|/0/myc box-dependent-interacting protein 1 isoform 1 [Mus musculus] 68039 692 3.833333333 2.283333333 -0.747457968 Down 0.557147693 Nmb neuromedin B K05223|1|4e-46|184|mmu:68039|neuromedin B GO:0042995//cell projection;GO:0042995//cell projection GO:0031705//bombesin receptor binding;GO:0031705//bombesin receptor binding GO:0046879//hormone secretion;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0015909//long-chain fatty acid transport;GO:0007631//feeding behavior;GO:0033500//carbohydrate homeostasis;GO:0046879//hormone secretion;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0015909//long-chain fatty acid transport;GO:0007631//feeding behavior;GO:0033500//carbohydrate homeostasis gi|602617438|ref|NP_001278209.1|/5.01961e-54/neuromedin-B isoform 1 precursor [Mus musculus] 232969 1204 12.17 9.043333333 -0.428402621 Down 0.557072474 Zfp428 zinc finger protein 428 - - - - "gi|148692385|gb|EDL24332.1|/1.38627e-72/zinc finger protein 428, isoform CRA_a, partial [Mus musculus]" 20411 5481.29 222.3466667 181.04 -0.296502287 Down 0.556969047 Sorbs1 sorbin and SH3 domain containing 1 K06086|1|0.0|1266|mmu:20411|sorbin and SH3 domain containing 1 GO:0005911//cell-cell junction;GO:0043231//intracellular membrane-bounded organelle;GO:0005912//adherens junction;GO:0043232;GO:0005901//caveola;GO:0044444//cytoplasmic part;GO:0005911//cell-cell junction;GO:0043231//intracellular membrane-bounded organelle;GO:0005912//adherens junction;GO:0043232;GO:0005901//caveola;GO:0044444//cytoplasmic part;GO:0005911//cell-cell junction;GO:0043231//intracellular membrane-bounded organelle;GO:0005912//adherens junction;GO:0043232;GO:0005901//caveola;GO:0044444//cytoplasmic part "GO:0005102//receptor binding;GO:0030674//protein binding, bridging;GO:0019900//kinase binding;GO:0005102//receptor binding;GO:0030674//protein binding, bridging;GO:0019900//kinase binding;GO:0005102//receptor binding;GO:0030674//protein binding, bridging;GO:0019900//kinase binding" GO:0032868//response to insulin;GO:0008610//lipid biosynthetic process;GO:0051130//positive regulation of cellular component organization;GO:0051017//actin filament bundle assembly;GO:0007044//cell-substrate junction assembly;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0005978//glycogen biosynthetic process;GO:0010828//positive regulation of glucose transport;GO:0032868//response to insulin;GO:0008610//lipid biosynthetic process;GO:0051130//positive regulation of cellular component organization;GO:0051017//actin filament bundle assembly;GO:0007044//cell-substrate junction assembly;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0005978//glycogen biosynthetic process;GO:0010828//positive regulation of glucose transport;GO:0032868//response to insulin;GO:0008610//lipid biosynthetic process;GO:0051130//positive regulation of cellular component organization;GO:0051017//actin filament bundle assembly;GO:0007044//cell-substrate junction assembly;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0005978//glycogen biosynthetic process;GO:0010828//positive regulation of glucose transport gi|78000154|ref|NP_001030136.1|/0/sorbin and SH3 domain-containing protein 1 isoform 5 [Mus musculus] 84704 1971 4.186666667 6.2 0.566466157 Up 0.556922035 Snurf SNRPN upstream reading frame K11100|1|6e-64|248|cjc:103787208|small nuclear ribonucleoprotein N GO:0030532//small nuclear ribonucleoprotein complex GO:0003676//nucleic acid binding GO:0009719;GO:0006396//RNA processing gi|675690021|ref|XP_009004277.1|/5.11982e-63/PREDICTED: small nuclear ribonucleoprotein-associated protein N isoform X2 [Callithrix jacchus] 14371 2110 0.75 1.836666667 1.292127317 Up 0.556762195 Fzd9 frizzled class receptor 9 K02842|1|0.0|1084|mmu:14371|frizzled 9/10 - - - - 12457 3069 26.07333333 32.94666667 0.337557475 Up 0.556564745 Noct nocturnin K18764|1|0.0|860|mmu:12457|nocturnin [EC:3.1.13.4] GO:0031981//nuclear lumen;GO:0035770//ribonucleoprotein granule GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0022618//ribonucleoprotein complex assembly;GO:0006351//transcription, DNA-templated;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" gi|33563248|ref|NP_033964.1|/0/nocturnin [Mus musculus] 75758 1330 5.98 8.416666667 0.493103498 Up 0.556536538 9130401M01Rik RIKEN cDNA 9130401M01 gene - - - - gi|21313070|ref|NP_083694.1|/3.49497e-160/uncharacterized protein C8orf76 homolog [Mus musculus] 14950 3879.23 8.353333333 11.33333333 0.440148332 Up 0.556517733 H13 histocompatibility 13 K09595|1|0.0|662|mmu:14950|minor histocompatibility antigen H13 [EC:3.4.23.-] - - - - 20446 2033 9.99 7.27 -0.458529314 Down 0.556480123 St6galnac2 "ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2" "K06616|1|0.0|763|mmu:20446|alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7B) [EC:2.4.99.-]" GO:0031228//intrinsic component of Golgi membrane "GO:0016757//transferase activity, transferring glycosyl groups" GO:0006464//cellular protein modification process "gi|31543707|ref|NP_033206.2|/0/alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 [Mus musculus]" 102103 4266.23 53.29333333 42.64333333 -0.321634857 Down 0.556461319 Mtus1 mitochondrial tumor suppressor 1 K10352|1|4e-16|91.3|obi:106880451|myosin heavy chain;K10402|2|3e-14|85.1|phu:Phum_PHUM600400|kinesin family member 20;K20283|4|3e-14|85.1|clv:102091665|golgin subfamily A member 4 GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0044763;GO:0032870//cellular response to hormone stimulus;GO:0044763 gi|54312129|ref|NP_001005863.1|/0/microtubule-associated tumor suppressor 1 homolog isoform 1 [Mus musculus] 100526474 85 3.073333333 1.68 -0.871343017 Down 0.556451916 Mir3074-1 microRNA 3074-1 - - - - - 67963 3278 18.05 23.23333333 0.364197318 Up 0.556329685 Npc2 Niemann-Pick type C2 K13443|1|1e-74|284|mmu:67963|Niemann-Pick C2 protein GO:0000323//lytic vacuole GO:0032934//sterol binding;GO:0005515//protein binding GO:0055092//sterol homeostasis;GO:0051707//response to other organism;GO:0030301//cholesterol transport;GO:0016125//sterol metabolic process;GO:0006720//isoprenoid metabolic process gi|74191829|dbj|BAE32866.1|/1.18091e-73/unnamed protein product [Mus musculus] 628900 2193 1.083333333 2.27 1.06721508 Up 0.556273271 Serpina3i "serine (or cysteine) peptidase inhibitor, clade A, member 3I" "K04525|1|0.0|775|mmu:628900|serpin peptidase inhibitor, clade A" - - - "gi|315709504|ref|NP_001186869.1|/0/serine (or cysteine) peptidase inhibitor, clade A, member 3I [Mus musculus]" 18950 2941 8.933333333 12.03333333 0.429765836 Up 0.556198052 Pnp purine-nucleoside phosphorylase K03783|1|1e-166|589|mmu:18950|purine-nucleoside phosphorylase [EC:2.4.2.1] GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0002054;GO:0043168//anion binding;GO:0016763//transferase activity, transferring pentosyl groups" GO:0006915//apoptotic process;GO:0006281//DNA repair;GO:0046102;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0044283//small molecule biosynthetic process;GO:0009151;GO:0042453;GO:0045582//positive regulation of T cell differentiation;GO:0008617//guanosine metabolic process;GO:0010212//response to ionizing radiation;GO:0009435//NAD biosynthetic process;GO:0042221//response to chemical;GO:0030183//B cell differentiation;GO:0032623//interleukin-2 production;GO:0009152//purine ribonucleotide biosynthetic process;GO:0046094;GO:0042098//T cell proliferation;GO:0046495//nicotinamide riboside metabolic process gi|7305395|ref|NP_038660.1|/1.16192e-165/purine nucleoside phosphorylase [Mus musculus] 67902 2161 7.313333333 10.02666667 0.455241041 Up 0.55615104 Sumf2 sulfatase modifying factor 2 K13444|1|1e-70|270|mgp:100542598|sulfatase modifying factor 1 GO:0043231//intracellular membrane-bounded organelle GO:0042802//identical protein binding;GO:0043169//cation binding - gi|77377292|ref|NP_080721.1|/2.85394e-171/sulfatase-modifying factor 2 precursor [Mus musculus] 12825 5564 40.79333333 32.42 -0.331449308 Down 0.556019407 Col3a1 "collagen, type III, alpha 1" "K19720|1|8e-145|518|mmu:12825|collagen, type III, alpha" - - - - 319720 2579 2.93 1.573333333 -0.897076306 Down 0.555981797 9630028I04Rik RIKEN cDNA 9630028I04 gene - - - - - 12927 3172.33 15.71666667 20.34 0.372024409 Up 0.555530483 Bcar1 breast cancer anti-estrogen resistance 1 K05726|1|0.0|1474|mmu:12927|breast cancer anti-estrogen resistance 1 GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0044424;GO:0016020//membrane;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0044424;GO:0016020//membrane GO:0019900//kinase binding;GO:0019904//protein domain specific binding;GO:0019900//kinase binding;GO:0019904//protein domain specific binding GO:0022610;GO:0006935//chemotaxis;GO:0038127//ERBB signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0050851//antigen receptor-mediated signaling pathway;GO:0010594//regulation of endothelial cell migration;GO:0035728//response to hepatocyte growth factor;GO:0022610;GO:0006935//chemotaxis;GO:0038127//ERBB signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0050851//antigen receptor-mediated signaling pathway;GO:0010594//regulation of endothelial cell migration;GO:0035728//response to hepatocyte growth factor gi|1184512|gb|AAA93381.1|/0/Crk-associated substrate [Mus musculus] 75533 829 2.083333333 0.94 -1.148161027 Down 0.554909925 Nme5 NME/NM23 family member 5 K00940|1|8e-121|435|mmu:75533|nucleoside-diphosphate kinase [EC:2.7.4.6] GO:0031514//motile cilium "GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0009209;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006915//apoptotic process;GO:0003341//cilium movement;GO:0007420//brain development;GO:0030031//cell projection assembly;GO:0007281//germ cell development;GO:0048232//male gamete generation;GO:0009132//nucleoside diphosphate metabolic process gi|110625839|ref|NP_542368.2|/6.21462e-120/nucleoside diphosphate kinase homolog 5 [Mus musculus] 14314 3609 26.47333333 20.74 -0.352123966 Down 0.554768889 Fstl1 follistatin-like 1 K06254|1|4e-11|73.6|tca:100141763|agrin;K04661|5|9e-11|72.4|gfr:102038114|follistatin - GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding - gi|149060525|gb|EDM11239.1|/0/follistatin-like 1 [Rattus norvegicus] 11637 1554.13 40.73333333 50.77333333 0.317861099 Up 0.554609049 Ak2 adenylate kinase 2 K00939|1|7e-128|460|mmu:11637|adenylate kinase [EC:2.7.4.3] GO:0044441;GO:0005740//mitochondrial envelope;GO:0019866//organelle inner membrane;GO:0044441;GO:0005740//mitochondrial envelope;GO:0019866//organelle inner membrane "GO:0032550;GO:0019205//nucleobase-containing compound kinase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032550;GO:0019205//nucleobase-containing compound kinase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0007417//central nervous system development;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006091//generation of precursor metabolites and energy;GO:0006144//purine nucleobase metabolic process;GO:0009151;GO:0044767//single-organism developmental process;GO:0009725//response to hormone;GO:0007417//central nervous system development;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006091//generation of precursor metabolites and energy;GO:0006144//purine nucleobase metabolic process;GO:0009151;GO:0044767//single-organism developmental process;GO:0009725//response to hormone "gi|34328230|ref|NP_058591.2|/1.98547e-127/adenylate kinase 2, mitochondrial isoform b [Mus musculus]" 56213 2051 63.57666667 78.90333333 0.311588872 Up 0.554430404 Htra1 HtrA serine peptidase 1 K08784|1|0.0|915|mmu:56213|HtrA serine peptidase 1 [EC:3.4.21.-] GO:0044444//cytoplasmic part GO:0004175//endopeptidase activity;GO:0019838//growth factor binding GO:0016049//cell growth;GO:0030509//BMP signaling pathway;GO:0019538//protein metabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway gi|229093139|ref|NP_062510.2|/0/serine protease HTRA1 precursor [Mus musculus] 213002 541 0.386666667 1.326666667 1.778643625 Up 0.554326977 Ifitm6 interferon induced transmembrane protein 6 K06566|1|1e-53|211|mmu:213002|interferon induced transmembrane protein GO:0031224//intrinsic component of membrane - - gi|75812952|ref|NP_001028804.1|/6.87132e-53/interferon induced transmembrane protein 6 [Mus musculus] 504186 2513 1.626666667 2.986666667 0.876617584 Up 0.553697018 Chrna10 "cholinergic receptor, nicotinic, alpha polypeptide 10" K04811|1|0.0|883|mmu:504186|nicotinic acetylcholine receptor alpha-10 GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0097060//synaptic membrane;GO:0043025//neuronal cell body GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0005261//cation channel activity GO:0042471//ear morphogenesis;GO:0006811//ion transport;GO:0007268//chemical synaptic transmission;GO:0051480//regulation of cytosolic calcium ion concentration gi|124487261|ref|NP_001074893.1|/0/neuronal acetylcholine receptor subunit alpha-10 precursor [Mus musculus] 54613 1593 17.52666667 22.47 0.358448483 Up 0.553659408 St3gal6 "ST3 beta-galactoside alpha-2,3-sialyltransferase 6" "K03792|1|0.0|663|mmu:54613|beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 10) [EC:2.4.99.10]" GO:0031228//intrinsic component of Golgi membrane GO:0008373//sialyltransferase activity GO:0006643//membrane lipid metabolic process;GO:0006464//cellular protein modification process;GO:0070741//response to interleukin-6;GO:0044723 "gi|148665765|gb|EDK98181.1|/0/ST3 beta-galactoside alpha-2,3-sialyltransferase 6, isoform CRA_b, partial [Mus musculus]" 68428 2769 20.59 26.18666667 0.346888599 Up 0.553452556 Steap3 STEAP family member 3 K10142|1|0.0|888|mmu:68428|metalloreductase STEAP3 [EC:1.16.1.-] GO:0031224//intrinsic component of membrane;GO:0005770//late endosome;GO:0031090//organelle membrane "GO:0043169//cation binding;GO:0016723//oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor" GO:0012502//induction of programmed cell death;GO:0044710;GO:0055080//cation homeostasis;GO:0000041//transition metal ion transport;GO:0015031//protein transport gi|568909603|ref|XP_006529909.1|/0/PREDICTED: metalloreductase STEAP3 isoform X2 [Mus musculus] 19221 5786 17.90333333 13.80333333 -0.375211519 Down 0.553085863 Ptgfrn prostaglandin F2 receptor negative regulator K06729|1|0.0|1670|mmu:19221|prostaglandin F2 receptor negative regulator GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane - GO:0006412//translation;GO:0006996//organelle organization "gi|148675683|gb|EDL07630.1|/0/prostaglandin F2 receptor negative regulator, partial [Mus musculus]" 71562 2332 5.28 7.503333333 0.506993721 Up 0.553038851 Afmid arylformamidase K01432|1|3e-162|575|mmu:71562|arylformamidase [EC:3.5.1.9] GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity GO:0006569//tryptophan catabolic process gi|21746157|ref|NP_082103.1|/2.25502e-161/kynurenine formamidase [Mus musculus] 11535 1381 6.263333333 8.716666667 0.47684588 Up 0.552935424 Adm adrenomedullin K12333|1|4e-93|344|mmu:11535|adrenomedullin GO:0044424;GO:0044421 GO:0001664//G-protein coupled receptor binding GO:0002027//regulation of heart rate;GO:0014020;GO:0009914//hormone transport;GO:0006915//apoptotic process;GO:0019229//regulation of vasoconstriction;GO:0043434//response to peptide hormone;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0042311//vasodilation;GO:0031960//response to corticosteroid;GO:0042476//odontogenesis;GO:0006898//receptor-mediated endocytosis;GO:0001892//embryonic placenta development;GO:0055001//muscle cell development;GO:0040007//growth;GO:0002237//response to molecule of bacterial origin;GO:0001570//vasculogenesis;GO:0043114//regulation of vascular permeability;GO:0044703;GO:0008283//cell proliferation;GO:0033554//cellular response to stress;GO:0001525//angiogenesis;GO:0006171//cAMP biosynthetic process;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0006700//C21-steroid hormone biosynthetic process gi|6752988|ref|NP_033757.1|/3.27767e-92/ADM precursor [Mus musculus] 436022 2189 4.956666667 3.193333333 -0.634307086 Down 0.552869608 Dnaaf3 "dynein, axonemal assembly factor 3" "K19752|1|0.0|1181|mmu:436022|dynein assembly factor 3, axonemal" GO:0044424 - GO:0042384//cilium assembly;GO:0043623//cellular protein complex assembly "gi|85702051|ref|NP_001028720.1|/0/dynein assembly factor 3, axonemal [Mus musculus]" 12453 2830 57.06666667 70.86333333 0.312391034 Up 0.55268156 Ccni cyclin I K10146|1|3e-27|126|lve:103069822|cyclin G2 - - GO:0007049//cell cycle "gi|148673282|gb|EDL05229.1|/0/cyclin I, isoform CRA_a, partial [Mus musculus]" 319259 997 2.683333333 4.313333333 0.684776929 Up 0.552296062 Bricd5 BRICHOS domain containing 5 - - - - "gi|148690381|gb|EDL22328.1|/2.27788e-112/RIKEN cDNA 9930021D14, isoform CRA_b, partial [Mus musculus]" 387203 79 0.01 0.59 5.882643049 Up 0.552267855 Mir207 microRNA 207 - - - - - 214384 5127 7.396666667 5.21 -0.505591889 Down 0.551628493 Myocd myocardin - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0019899//enzyme binding;GO:0046332//SMAD binding;GO:0003712//transcription cofactor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0019899//enzyme binding;GO:0046332//SMAD binding GO:0055007//cardiac muscle cell differentiation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0051155//positive regulation of striated muscle cell differentiation;GO:0003205//cardiac chamber development;GO:0051241;GO:0045445//myoblast differentiation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0001558//regulation of cell growth;GO:0051152//positive regulation of smooth muscle cell differentiation;GO:0001666//response to hypoxia;GO:0003301//physiological cardiac muscle hypertrophy;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010830//regulation of myotube differentiation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0003256//regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0048844//artery morphogenesis;GO:0072537//fibroblast activation;GO:0016573//histone acetylation;GO:0006939//smooth muscle contraction;GO:0008283//cell proliferation;GO:0010659//cardiac muscle cell apoptotic process;GO:0051099//positive regulation of binding;GO:0030324//lung development;GO:0055007//cardiac muscle cell differentiation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0051155//positive regulation of striated muscle cell differentiation;GO:0003205//cardiac chamber development;GO:0051241;GO:0045445//myoblast differentiation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0001558//regulation of cell growth;GO:0051152//positive regulation of smooth muscle cell differentiation;GO:0001666//response to hypoxia;GO:0003301//physiological cardiac muscle hypertrophy;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010830//regulation of myotube differentiation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0003256//regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0048844//artery morphogenesis;GO:0072537//fibroblast activation;GO:0016573//histone acetylation;GO:0006939//smooth muscle contraction;GO:0008283//cell proliferation;GO:0010659//cardiac muscle cell apoptotic process;GO:0051099//positive regulation of binding;GO:0030324//lung development gi|154240675|ref|NP_660118.3|/0/myocardin isoform A [Mus musculus] 140483 1653 3.536666667 5.36 0.59984275 Up 0.55122419 Hnmt histamine N-methyltransferase K00546|1|5e-162|573|mmu:140483|histamine N-methyltransferase [EC:2.1.1.8] GO:0031981//nuclear lumen;GO:0042995//cell projection GO:0008170//N-methyltransferase activity GO:0007417//central nervous system development;GO:0010243//response to organonitrogen compound;GO:0006970//response to osmotic stress;GO:0031960//response to corticosteroid;GO:0034097//response to cytokine;GO:0008152//metabolic process;GO:0009607//response to biotic stimulus "gi|148676210|gb|EDL08157.1|/3.47816e-163/histamine N-methyltransferase, isoform CRA_a, partial [Mus musculus]" 20183 1789.21 52.65333333 65.20666667 0.308494605 Up 0.551045545 Rxrg retinoid X receptor gamma K08526|1|0.0|774|mmu:20183|retinoid X receptor gamma GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0003708//retinoic acid receptor activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0003708//retinoic acid receptor activity GO:0006366//transcription from RNA polymerase II promoter;GO:0014706//striated muscle tissue development;GO:0009755//hormone-mediated signaling pathway;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0044767//single-organism developmental process;GO:0042552//myelination;GO:0033993//response to lipid;GO:0006366//transcription from RNA polymerase II promoter;GO:0014706//striated muscle tissue development;GO:0009755//hormone-mediated signaling pathway;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0044767//single-organism developmental process;GO:0042552//myelination;GO:0033993//response to lipid gi|6677829|ref|NP_033133.1|/0/retinoic acid receptor RXR-gamma isoform 1 [Mus musculus] 664849 1401 19.16 24.47333333 0.353113053 Up 0.550876302 Gm7367 1110014K08Rik pseudogene - - - - gi|28892683|ref|NP_795876.1|/7.00293e-82/UBA-like domain-containing protein 2 [Mus musculus] 12879 1838 3.543333333 2.08 -0.768523663 Down 0.550330964 Cys1 cystin 1 - GO:0005815//microtubule organizing center;GO:0005930//axoneme;GO:0044425;GO:0005815//microtubule organizing center;GO:0005930//axoneme;GO:0044425;GO:0005815//microtubule organizing center;GO:0005930//axoneme;GO:0044425 GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0043583//ear development;GO:0043583//ear development;GO:0043583//ear development "gi|148705044|gb|EDL36991.1|/9.82908e-82/cystin 1, partial [Mus musculus]" 102466255 117 0.593333333 1.606666667 1.437155905 Up 0.550189928 Mir1291 microRNA 1291 - - - - - 17913 5292.62 61.69333333 49.68666667 -0.312255839 Down 0.550067697 Myo1c myosin IC K10356|1|0.0|1952|mmu:17913|myosin I GO:0005884//actin filament;GO:0016461//unconventional myosin complex;GO:0031988//membrane-bounded vesicle;GO:0016323//basolateral plasma membrane;GO:0005902//microvillus;GO:0032589//neuron projection membrane;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005884//actin filament;GO:0016461//unconventional myosin complex;GO:0031988//membrane-bounded vesicle;GO:0016323//basolateral plasma membrane;GO:0005902//microvillus;GO:0032589//neuron projection membrane;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0005884//actin filament;GO:0016461//unconventional myosin complex;GO:0031988//membrane-bounded vesicle;GO:0016323//basolateral plasma membrane;GO:0005902//microvillus;GO:0032589//neuron projection membrane;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum "GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0008289//lipid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0008289//lipid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0008289//lipid binding;GO:0042623//ATPase activity, coupled" GO:0050658//RNA transport;GO:0090313;GO:0009967//positive regulation of signal transduction;GO:0070830//bicellular tight junction assembly;GO:0030335//positive regulation of cell migration;GO:0050658//RNA transport;GO:0090313;GO:0009967//positive regulation of signal transduction;GO:0070830//bicellular tight junction assembly;GO:0030335//positive regulation of cell migration;GO:0050658//RNA transport;GO:0090313;GO:0009967//positive regulation of signal transduction;GO:0070830//bicellular tight junction assembly;GO:0030335//positive regulation of cell migration gi|226693542|sp|Q9WTI7.2|MYO1C_MOUSE/0/RecName: Full=Unconventional myosin-Ic; AltName: Full=Myosin I beta; Short=MMI-beta; Short=MMIb 382051 3514 10.48666667 7.716666667 -0.442506477 Down 0.550067697 Pdp2 pyruvate dehyrogenase phosphatase catalytic subunit 2 K01102|1|0.0|1045|mmu:382051|pyruvate dehydrogenase phosphatase [EC:3.1.3.43] GO:0005759//mitochondrial matrix GO:0043169//cation binding;GO:0004722//protein serine/threonine phosphatase activity GO:0044699;GO:0006470//protein dephosphorylation gi|60360396|dbj|BAD90442.1|/0/mKIAA1348 protein [Mus musculus] 735268 109 0.656666667 1.686666667 1.360941755 Up 0.54984204 Mir680-1 microRNA 680-1 - - - - "gi|148668336|gb|EDL00662.1|/2.53712e-06/mCG1042759, partial [Mus musculus]" 15939 3272 9.826666667 7.176666667 -0.453388205 Down 0.549625785 Ier5 immediate early response 5 - - - - gi|6754284|ref|NP_034630.1|/4.14287e-111/immediate early response gene 5 protein [Mus musculus] 245195 610 0.663333333 1.696666667 1.354897226 Up 0.54944714 Retnlg resistin like gamma K13438|1|6e-20|99.4|amj:102571173|resistin - GO:0005102//receptor binding - gi|225007619|ref|NP_853627.2|/1.21893e-55/resistin-like gamma precursor [Mus musculus] 51812 1904.13 21.98666667 27.85333333 0.341221094 Up 0.54921208 Mcrs1 microspherule protein 1 K11674|1|0.0|793|mmu:51812|microspherule protein 1 GO:0044665//MLL1/2 complex;GO:0000790//nuclear chromatin;GO:0044665//MLL1/2 complex;GO:0000790//nuclear chromatin GO:0010485//H4 histone acetyltransferase activity;GO:0010485//H4 histone acetyltransferase activity "GO:0043967//histone H4 acetylation;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006351//transcription, DNA-templated;GO:0043967//histone H4 acetylation;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006351//transcription, DNA-templated" gi|803043954|ref|XP_012029724.1|/0/PREDICTED: microspherule protein 1 isoform X1 [Ovis aries] 69123 1346 1.496666667 0.52 -1.525169416 Down 0.548572718 Eci3 enoyl-Coenzyme A delta isomerase 3 "K13239|1|6e-139|496|mmu:23986|peroxisomal 3,2-trans-enoyl-CoA isomerase [EC:5.3.3.8]" GO:0044439 "GO:0005515//protein binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds" GO:0009062//fatty acid catabolic process "gi|21312210|ref|NP_081223.1|/8.1545e-173/enoyl-CoA delta isomerase 3, peroxisomal [Mus musculus]" 73921 811 7.663333333 10.39666667 0.440077087 Up 0.548450487 Scpep1os "serine carboxypeptidase 1, opposite strand" K09646|1|2e-10|68.2|mmu:74617|serine carboxypeptidase 1 [EC:3.4.16.-] GO:0044444//cytoplasmic part GO:0004180//carboxypeptidase activity GO:0019538//protein metabolic process gi|148683912|gb|EDL15859.1|/2.49224e-17/mCG1050994 [Mus musculus] 69876 1116.84 6.636666667 9.146666667 0.46278726 Up 0.548431682 Thap3 "THAP domain containing, apoptosis associated protein 3" K09228|1|3e-14|82.0|gja:107120690|KRAB domain-containing zinc finger protein - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0043169//cation binding - "gi|148682965|gb|EDL14912.1|/1.09431e-72/THAP domain containing, apoptosis associated protein 3, isoform CRA_a, partial [Mus musculus]" 94094 2600 2.146666667 3.61 0.749900649 Up 0.547482041 Trim34a tripartite motif-containing 34A K11999|1|0.0|974|mmu:94094|tripartite motif-containing protein 6/22/34 - - - gi|154350234|ref|NP_109609.2|/0/tripartite motif-containing protein 34A [Mus musculus] 57370 1998 8.17 10.97666667 0.426032028 Up 0.547087141 B4galt3 "UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3" "K07968|1|0.0|662|mmu:57370|beta-1,4-galactosyltransferase 3 [EC:2.4.1.90 2.4.1.38 2.4.1.-]" GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0035250//UDP-galactosyltransferase activity GO:0006464//cellular protein modification process "gi|817269964|ref|XP_012305040.1|/0/PREDICTED: beta-1,4-galactosyltransferase 3 isoform X1 [Aotus nancymaae]" 17874 1947 7.043333333 9.626666667 0.450777975 Up 0.546917898 Myd88 myeloid differentiation primary response gene 88 K04729|1|5e-159|563|mmu:17874|myeloid differentiation primary response protein MyD88 GO:0031090//organelle membrane;GO:0032991//macromolecular complex;GO:0044327//dendritic spine head;GO:0044444//cytoplasmic part GO:0019904//protein domain specific binding;GO:0032813//tumor necrosis factor receptor superfamily binding GO:0006954//inflammatory response;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0009612//response to mechanical stimulus;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0019724//B cell mediated immunity;GO:0042742//defense response to bacterium;GO:0007254//JNK cascade;GO:0001819//positive regulation of cytokine production;GO:0002237//response to molecule of bacterial origin;GO:0032606//type I interferon production;GO:0006366//transcription from RNA polymerase II promoter;GO:0002224//toll-like receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0044126;GO:0034097//response to cytokine;GO:0042033//chemokine biosynthetic process;GO:0048255//mRNA stabilization "gi|148677277|gb|EDL09224.1|/4.00778e-169/myeloid differentiation primary response gene 88, isoform CRA_a, partial [Mus musculus]" 234309 1115 26.1 20.57 -0.343508013 Down 0.546128098 Cbr4 carbonyl reductase 4 K11539|1|4e-120|433|mmu:234309|carbonyl reductase 4 [EC:1.1.1.-] GO:0044429 "GO:0043168//anion binding;GO:0048037//cofactor binding;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor" GO:0006631//fatty acid metabolic process;GO:0030647;GO:0051260//protein homooligomerization gi|269784762|ref|NP_663570.2|/3.00711e-119/carbonyl reductase family member 4 [Mus musculus] 74356 3216.86 6.723333333 4.68 -0.522668148 Down 0.545526345 4931428F04Rik RIKEN cDNA 4931428F04 gene - - - - "gi|148679316|gb|EDL11263.1|/0/RIKEN cDNA 4931428F04, isoform CRA_b, partial [Mus musculus]" 100306954 132 1.536666667 2.826666667 0.879297514 Up 0.545460529 Snora17 "small nucleolar RNA, H/ACA box 17" - - - - - 231691 1164 0.343333333 1.23 1.840976479 Up 0.545338298 Sds serine dehydratase K17989|1|2e-160|567|mmu:231691|L-serine/L-threonine ammonia-lyase [EC:4.3.1.17 4.3.1.19] GO:0043231//intracellular membrane-bounded organelle GO:0043168//anion binding;GO:0016841//ammonia-lyase activity;GO:0042802//identical protein binding GO:0001101//response to acid chemical;GO:0010243//response to organonitrogen compound;GO:0006090//pyruvate metabolic process;GO:0009991//response to extracellular stimulus;GO:0006563//L-serine metabolic process;GO:0006006//glucose metabolic process gi|568937136|ref|XP_006530361.1|/3.73218e-160/PREDICTED: L-serine dehydratase/L-threonine deaminase isoform X1 [Mus musculus] 100316665 121 0.573333333 0.01 -5.841302254 Down 0.545263079 Mir466i microRNA 466i - - - - - 12905 1650 9.373333333 12.47333333 0.412212964 Up 0.54515025 Cradd CASP2 and RIPK1 domain containing adaptor with death domain K02832|1|5e-99|364|mmu:12905|CASP2 and RIPK1 domain containing adaptor with death domain GO:0043231//intracellular membrane-bounded organelle GO:0019904//protein domain specific binding "GO:0012502//induction of programmed cell death;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006915//apoptotic process" gi|6753516|ref|NP_034080.1|/3.90785e-98/death domain-containing protein CRADD [Mus musculus] 100302499 120 0.01 0.566666667 5.824428435 Up 0.545112641 Snora3 "small nucleolar RNA, H/ACA box 3" - - - - - 14824 2348 61.70333333 76.06666667 0.301915957 Up 0.544933995 Grn granulin K02599|1|9e-20|101|lgi:LOTGIDRAFT_195554|Notch GO:0043231//intracellular membrane-bounded organelle;GO:0044421 GO:0005102//receptor binding GO:0051094//positive regulation of developmental process;GO:0043627//response to estrogen;GO:0007617//mating behavior;GO:0001824//blastocyst development;GO:0006897//endocytosis;GO:0010975//regulation of neuron projection development;GO:0008284//positive regulation of cell proliferation gi|224967126|ref|NP_032201.2|/0/granulins precursor [Mus musculus] 21807 1849.81 135.8866667 165.8266667 0.287272122 Up 0.544680131 Tsc22d1 "TSC22 domain family, member 1" K10955|1|4e-06|57.4|tup:102470397|intestinal mucin-2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity "GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation" gi|295293202|ref|NP_997535.2|/0/TSC22 domain family protein 1 isoform 1 [Mus musculus] 65079 1890 4.42 6.4 0.534025535 Up 0.544661326 Rtn4r reticulon 4 receptor K16659|1|0.0|831|mmu:65079|reticulon-4 receptor GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007409//axonogenesis gi|12667794|ref|NP_075358.1|/0/reticulon-4 receptor precursor [Mus musculus] 54608 2903 2.1 0.993333333 -1.080039498 Down 0.544247621 Abhd2 abhydrolase domain containing 2 K13697|1|0.0|850|mmu:54608|abhydrolase domain-containing protein 2 GO:0031224//intrinsic component of membrane GO:0052689//carboxylic ester hydrolase activity GO:0016477//cell migration;GO:0006950//response to stress gi|537205210|gb|ERE79843.1|/0/abhydrolase domain-containing protein 2 [Cricetulus griseus] 17285 2235 9.256666667 12.32333333 0.412827866 Up 0.544153597 Meox1 mesenchyme homeobox 1 K09322|1|8e-132|473|mmu:17285|homeobox protein MOX GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0019904//protein domain specific binding GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter gi|6754680|ref|NP_034921.1|/6.70289e-131/homeobox protein MOX-1 [Mus musculus] 72012 599.78 1.893333333 3.266666667 0.786890819 Up 0.543636466 1600020E01Rik RIKEN cDNA 1600020E01 gene - - - - - 54633 1150.87 19.98333333 25.23333333 0.336533547 Up 0.54353304 Pqbp1 polyglutamine binding protein 1 K12865|1|3e-127|457|mmu:54633|polyglutamine-binding protein 1 GO:0043005//neuron projection;GO:0031981//nuclear lumen;GO:0035770//ribonucleoprotein granule;GO:0043005//neuron projection;GO:0031981//nuclear lumen;GO:0035770//ribonucleoprotein granule;GO:0043005//neuron projection;GO:0031981//nuclear lumen;GO:0035770//ribonucleoprotein granule - "GO:0022618//ribonucleoprotein complex assembly;GO:0006351//transcription, DNA-templated;GO:0022618//ribonucleoprotein complex assembly;GO:0006351//transcription, DNA-templated;GO:0022618//ribonucleoprotein complex assembly;GO:0006351//transcription, DNA-templated" gi|357527414|ref|NP_001239458.1|/4.08039e-131/polyglutamine-binding protein 1 isoform 2 [Mus musculus] 433855 453 8.4 6.08 -0.466318004 Down 0.543392004 AI506816 expressed sequence AI506816 "K10279|1|9e-17|91.7|fpg:101911127|F-box and leucine-rich repeat protein 13;K14684|3|2e-12|77.4|ngi:103726559|solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41;K04257|4|1e-06|58.2|tup:102483054|olfactory receptor;K14702|5|4e-06|56.2|cmy:102932003|solute carrier family 26 (sodium-independent chloride/iodide transporter), member 4" - - - "gi|148701441|gb|EDL33388.1|/2.46139e-17/mCG1045525, partial [Mus musculus]" 93679 3262 19.48333333 24.71666667 0.343243668 Up 0.543326188 Trim8 tripartite motif-containing 8 K12001|1|0.0|1159|mmu:93679|tripartite motif-containing protein 8 [EC:2.3.2.27] GO:0016604//nuclear body GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity - "gi|148710059|gb|EDL42005.1|/0/tripartite motif protein 8, isoform CRA_b, partial [Mus musculus]" 107242 1541.57 23.95 30.00333333 0.325097135 Up 0.543175749 AI837181 expressed sequence AI837181 - - - - "gi|148701182|gb|EDL33129.1|/3.69906e-135/expressed sequence AI837181, isoform CRA_b, partial [Mus musculus]" 545276 2442 6.72 9.196666667 0.452649818 Up 0.543044116 Gal3st3 galactose-3-O-sulfotransferase 3 K09676|1|0.0|762|mmu:545276|galactose-3-O-sulfotransferase 3 [EC:2.8.2.-] GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane GO:0032550;GO:0050694//galactose 3-O-sulfotransferase activity GO:0006029//proteoglycan metabolic process;GO:0006022;GO:0044723 gi|85701542|ref|NP_001019888.1|/0/galactose-3-O-sulfotransferase 3 [Mus musculus] 69109 1243 8.216666667 11.02333333 0.423935399 Up 0.542733837 Fam58b "family with sequence similarity 58, member B" K15188|1|2e-12|76.3|mze:101480881|cyclin T - GO:0019900//kinase binding "GO:0006351//transcription, DNA-templated" gi|37574068|ref|NP_932106.1|/4.63837e-119/cyclin-related protein FAM58B [Mus musculus] 210376 2457 5.753333333 3.913333333 -0.556000056 Down 0.542715033 Mtmr9 myotubularin related protein 9 K18084|1|0.0|1115|mmu:210376|myotubularin-related protein 9 GO:0044424 GO:0042578//phosphoric ester hydrolase activity GO:0019222//regulation of metabolic process;GO:0006796//phosphate-containing compound metabolic process gi|33563378|ref|NP_808262.1|/0/myotubularin-related protein 9 [Mus musculus] 12562 4004 133.69 108.99 -0.294695784 Down 0.542696228 Cdh5 cadherin 5 "K06533|1|0.0|1456|mmu:12562|cadherin 5, type 2, VE-cadherin" GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0044464 GO:0019902//phosphatase binding;GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion;GO:0008283//cell proliferation;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0001568//blood vessel development gi|38490561|ref|NP_033998.2|/0/cadherin-5 preproprotein [Mus musculus] 50935 2389.68 38.31666667 47.55 0.311473281 Up 0.542602204 St6galnac6 "ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6" "K03376|1|0.0|442|cge:100757138|N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7F) [EC:2.4.99.-]" GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane GO:0008373//sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0008373//sialyltransferase activity GO:0008037//cell recognition;GO:0006464//cellular protein modification process;GO:0006664//glycolipid metabolic process;GO:0006672//ceramide metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0008037//cell recognition;GO:0006464//cellular protein modification process;GO:0006664//glycolipid metabolic process;GO:0006672//ceramide metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0008037//cell recognition;GO:0006464//cellular protein modification process;GO:0006664//glycolipid metabolic process;GO:0006672//ceramide metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0008037//cell recognition;GO:0006464//cellular protein modification process;GO:0006664//glycolipid metabolic process;GO:0006672//ceramide metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0008037//cell recognition;GO:0006464//cellular protein modification process;GO:0006664//glycolipid metabolic process;GO:0006672//ceramide metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0008037//cell recognition;GO:0006464//cellular protein modification process;GO:0006664//glycolipid metabolic process;GO:0006672//ceramide metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0008037//cell recognition;GO:0006464//cellular protein modification process;GO:0001573//ganglioside metabolic process;GO:0009311//oligosaccharide metabolic process "gi|625209977|ref|XP_003507214.2|/0/PREDICTED: alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 [Cricetulus griseus]" 18218 4839 11.01333333 8.22 -0.422040887 Down 0.542085073 Dusp8 dual specificity phosphatase 8 K04459|1|0.0|924|mmu:18218|dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] - - - gi|6679156|ref|NP_032774.1|/0/dual specificity protein phosphatase 8 [Mus musculus] 77622 1909 3.176666667 4.846666667 0.60947915 Up 0.541962842 Apex2 apurinic/apyrimidinic endonuclease 2 K10772|1|0.0|958|mmu:77622|AP endonuclease 2 [EC:4.2.99.18] GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0016835//carbon-oxygen lyase activity GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress "gi|148675569|gb|EDL07516.1|/0/apurinic/apyrimidinic endonuclease 2, isoform CRA_d, partial [Mus musculus]" 111241 1594.83 0.563333333 0.01 -5.815916936 Down 0.541727782 Hmga1-rs1 "high mobility group AT-hook I, related sequence 1" K09282|1|4e-06|55.5|ssc:100157848|high mobility group AT-hook protein 1 GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0000792//heterochromatin;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0000792//heterochromatin GO:0016835//carbon-oxygen lyase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0016835//carbon-oxygen lyase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0003677//DNA binding "GO:0090398//cellular senescence;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0034728//nucleosome organization;GO:0044764;GO:0006342//chromatin silencing;GO:0065003;GO:0048232//male gamete generation;GO:0048584;GO:0031507//heterochromatin assembly;GO:0006281//DNA repair;GO:0090398//cellular senescence;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0044764;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048584;GO:0031507//heterochromatin assembly;GO:0022414//reproductive process;GO:0043933;GO:0006281//DNA repair" gi|625207681|ref|XP_007644976.1|/3.83146e-26/PREDICTED: high mobility group protein HMG-I/HMG-Y isoform X2 [Cricetulus griseus] 12909 1474 6.256666667 8.61 0.460618993 Up 0.541492723 Crcp calcitonin gene-related peptide-receptor component protein - GO:0030141//secretory granule;GO:0042575;GO:0016020//membrane GO:0034062//RNA polymerase activity;GO:0004930//G-protein coupled receptor activity;GO:0036094//small molecule binding "GO:0006952//defense response;GO:0002252;GO:0006351//transcription, DNA-templated;GO:0007186//G-protein coupled receptor signaling pathway" gi|6681011|ref|NP_031787.1|/2.34512e-75/DNA-directed RNA polymerase III subunit RPC9 [Mus musculus] 11655 2703.21 119.1133333 97.12 -0.294494588 Down 0.541426906 Alas1 aminolevulinic acid synthase 1 K00643|1|0.0|1249|mmu:11655|5-aminolevulinate synthase [EC:2.3.1.37] GO:0031981//nuclear lumen;GO:0044429;GO:0031981//nuclear lumen;GO:0044429 GO:0043168//anion binding;GO:0016749//N-succinyltransferase activity;GO:0043168//anion binding;GO:0016749//N-succinyltransferase activity GO:0010038//response to metal ion;GO:0097305//response to alcohol;GO:0046683//response to organophosphorus;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0014070//response to organic cyclic compound;GO:0009991//response to extracellular stimulus;GO:0032868//response to insulin;GO:0006950//response to stress;GO:0010038//response to metal ion;GO:0097305//response to alcohol;GO:0046683//response to organophosphorus;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0014070//response to organic cyclic compound;GO:0009991//response to extracellular stimulus;GO:0032868//response to insulin;GO:0006950//response to stress "gi|160707967|ref|NP_065584.2|/0/5-aminolevulinate synthase, nonspecific, mitochondrial precursor [Mus musculus]" 93757 1163 12.03333333 9.053333333 -0.410515358 Down 0.541342284 Immp2l IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) K09648|1|1e-102|375|bacu:103018190|mitochondrial inner membrane protease subunit 2 [EC:3.4.21.-] - - - - 55990 3336 16.54333333 12.77333333 -0.373114894 Down 0.541314077 Fmo2 flavin containing monooxygenase 2 K00485|1|0.0|1042|mmu:55990|dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8] GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane "GO:0000166//nucleotide binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen" GO:0055114//oxidation-reduction process;GO:0019748//secondary metabolic process;GO:0046496//nicotinamide nucleotide metabolic process gi|31542819|ref|NP_061369.2|/0/dimethylaniline monooxygenase [N-oxide-forming] 2 [Mus musculus] 171429 3329 3.266666667 4.956666667 0.601550993 Up 0.541229456 Slc26a6 "solute carrier family 26, member 6" "K14704|1|0.0|1146|mmu:171429|solute carrier family 26 (sulfate anion transporter), member 6" GO:0016021//integral component of membrane GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity GO:0015698//inorganic anion transport;GO:0044763;GO:0015718//monocarboxylic acid transport "gi|148689371|gb|EDL21318.1|/0/solute carrier family 26, member 6, isoform CRA_a [Mus musculus]" 223775 2419 92.71333333 113.3366667 0.289765941 Up 0.540646508 Pim3 proviral integration site 3 K08807|1|6e-173|610|tup:102468521|proto-oncogene serine/threonine-protein kinase Pim-3 [EC:2.7.11.1] GO:0044424 GO:0032550;GO:0004672//protein kinase activity GO:0000278//mitotic cell cycle;GO:0006915//apoptotic process;GO:0006468//protein phosphorylation;GO:0035773//insulin secretion involved in cellular response to glucose stimulus gi|3800869|gb|AAC68900.1|/0/serine threonine kinase [Rattus norvegicus] 78428 1180.92 7.533333333 10.16333333 0.432013378 Up 0.540590094 Pym1 "PYM homolog 1, exon junction complex associated factor" K14294|1|2e-69|265|mmu:78428|partner of Y14 and mago GO:0043234//protein complex;GO:0044428//nuclear part;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0043021//ribonucleoprotein complex binding;GO:0043021//ribonucleoprotein complex binding;GO:0043021//ribonucleoprotein complex binding;GO:0043021//ribonucleoprotein complex binding GO:0006412//translation;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006412//translation;GO:0006412//translation;GO:0006412//translation gi|625207478|ref|XP_003506249.2|/5.66088e-81/PREDICTED: partner of Y14 and mago isoform X2 [Cricetulus griseus] 15983 1980 22.11 27.86666667 0.333841416 Up 0.540486667 Ifrd2 interferon-related developmental regulator 2 "K13855|1|8e-56|221|tup:102497672|solute carrier family 4 (anion exchanger), member 2" - - - gi|13385396|ref|NP_080179.1|/6.73578e-180/interferon-related developmental regulator 2 [Mus musculus] 217378 4713 4.953333333 3.276666667 -0.596170794 Down 0.540411448 Dnajc27 DnaJ heat shock protein family (Hsp40) member C27 K19372|1|4e-155|552|mmu:217378|DnaJ homolog subfamily C member 27 - - - - 208501 494 36.02666667 44.64 0.309271853 Up 0.540279815 1810043H04Rik RIKEN cDNA 1810043H04 gene - GO:0043231//intracellular membrane-bounded organelle - - "gi|148702781|gb|EDL34728.1|/6.40477e-45/mCG15041, partial [Mus musculus]" 66441 832.53 2.243333333 3.683333333 0.71536796 Up 0.540157584 Magohb "mago homolog B, exon junction complex core component" K12877|1|4e-86|319|ocu:100344696|protein mago nashi GO:0043234//protein complex;GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding GO:0006396//RNA processing;GO:0050658//RNA transport;GO:0000956//nuclear-transcribed mRNA catabolic process gi|655888550|ref|XP_002722203.2|/3.25445e-85/PREDICTED: protein mago nashi homolog 2 [Oryctolagus cuniculus] 27428 6838 11.92666667 9.003333333 -0.405659748 Down 0.539715672 Shroom3 shroom family member 3 K18625|1|0.0|3580|mmu:27428|protein Shroom GO:0070161;GO:0015630//microtubule cytoskeleton;GO:0044459;GO:0005911//cell-cell junction;GO:0070161;GO:0015630//microtubule cytoskeleton;GO:0044459;GO:0005911//cell-cell junction;GO:0070161;GO:0015630//microtubule cytoskeleton;GO:0044459;GO:0005911//cell-cell junction GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0014020;GO:0022604//regulation of cell morphogenesis;GO:0007010//cytoskeleton organization;GO:0002064//epithelial cell development;GO:0014020;GO:0022604//regulation of cell morphogenesis;GO:0007010//cytoskeleton organization;GO:0002064//epithelial cell development;GO:0014020;GO:0022604//regulation of cell morphogenesis;GO:0007010//cytoskeleton organization;GO:0002064//epithelial cell development gi|117606395|ref|NP_056571.2|/0/protein Shroom3 isoform 1 [Mus musculus] 74569 4607 12.50333333 9.453333333 -0.40341773 Down 0.53966866 Ttc17 tetratricopeptide repeat domain 17 - - - - gi|124430551|ref|NP_898929.2|/0/tetratricopeptide repeat protein 17 [Mus musculus] 59045 2100 11.24666667 14.67333333 0.383699172 Up 0.53963105 Stard3 START domain containing 3 "K16931|1|7e-31|138|gga:395421|steroidogenic acute regulatory protein, mitochondrial" GO:0031224//intrinsic component of membrane;GO:0005768//endosome GO:0032934//sterol binding;GO:0015248//sterol transporter activity GO:0006700//C21-steroid hormone biosynthetic process;GO:0010876//lipid localization;GO:0051234//establishment of localization gi|10946984|ref|NP_067522.1|/0/stAR-related lipid transfer protein 3 [Mus musculus] 100217420 164 1.54 2.796666667 0.860777959 Up 0.539245553 Snora81 "small nucleolar RNA, H/ACA box 81" - - - - - 66397 1253 82.20666667 100.41 0.288575656 Up 0.538991688 Sar1b secretion associated Ras related GTPase 1B K07953|1|2e-110|401|mmu:66397|GTP-binding protein SAR1 [EC:3.6.5.-] GO:0000139//Golgi membrane;GO:0030134//ER to Golgi transport vesicle GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0043169//cation binding GO:0006901//vesicle coating;GO:0016482//cytosolic transport;GO:0015031//protein transport;GO:0006487//protein N-linked glycosylation;GO:0009154//purine ribonucleotide catabolic process;GO:0002478 gi|795530233|ref|XP_011714856.1|/2.0967e-111/PREDICTED: GTP-binding protein SAR1b isoform X1 [Macaca nemestrina] 328365 7532.14 22.73666667 17.91333333 -0.343986941 Down 0.538831848 Zmiz1 "zinc finger, MIZ-type containing 1" K04706|1|9e-19|100|bmy:Bm1_48650|E3 SUMO-protein ligase PIAS1;K16063|2|4e-17|94.7|aga:AgaP_AGAP005031|E3 SUMO-protein ligase PIAS2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0048514//blood vessel morphogenesis;GO:0043009//chordate embryonic development;GO:0040007//growth;GO:0009887//organ morphogenesis;GO:0007568//aging;GO:0008284//positive regulation of cell proliferation;GO:0007028//cytoplasm organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0048514//blood vessel morphogenesis;GO:0043009//chordate embryonic development;GO:0040007//growth;GO:0009887//organ morphogenesis;GO:0007568//aging;GO:0008284//positive regulation of cell proliferation;GO:0007028//cytoplasm organization;GO:0006366//transcription from RNA polymerase II promoter "gi|148669477|gb|EDL01424.1|/0/retinoic acid induced 17, isoform CRA_a, partial [Mus musculus]" 52633 1292 13.76333333 17.69666667 0.362647723 Up 0.538700214 Nit2 "nitrilase family, member 2" K13566|1|3e-157|556|mmu:52633|omega-amidase [EC:3.5.1.3] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle "GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0008152//metabolic process gi|12963555|ref|NP_075664.1|/2.92818e-156/omega-amidase NIT2 [Mus musculus] 17312 1498 1.653333333 2.933333333 0.827163403 Up 0.53848396 Clec10a "C-type lectin domain family 10, member A" K06721|1|7e-163|576|mmu:17312|C-type lectin domain family 10 member A GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding - gi|6754688|ref|NP_034926.1|/2.33906e-163/C-type lectin domain family 10 member A isoform 2 [Mus musculus] 16658 3389 10.07 13.23666667 0.394476177 Up 0.538474557 Mafb "v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)" K09036|1|2e-122|442|mmu:16658|transcription factor MAFB GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005515//protein binding GO:0006366//transcription from RNA polymerase II promoter;GO:0007389//pattern specification process;GO:0021546//rhombomere development;GO:0030218//erythrocyte differentiation;GO:0042471//ear morphogenesis gi|23308601|ref|NP_034788.1|/2.06477e-121/transcription factor MafB [Mus musculus] 100041621 2061 0.553333333 0.01 -5.790076931 Down 0.538436948 Gm3435 predicted gene 3435 - - - - gi|183074537|ref|NP_001116844.1|/0/uncharacterized protein LOC100041621 [Mus musculus] 217864 2725 2.666666667 1.44 -0.888968688 Down 0.538418143 Rcor1 REST corepressor 1 K11829|1|0.0|682|mmu:217864|REST corepressor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0000975//regulatory region DNA binding "GO:0006351//transcription, DNA-templated;GO:0030219//megakaryocyte differentiation;GO:0016575//histone deacetylation" "gi|148686697|gb|EDL18644.1|/0/REST corepressor 1, isoform CRA_a, partial [Mus musculus]" 74155 3034 17.69 22.44666667 0.343567172 Up 0.538098462 Errfi1 ERBB receptor feedback inhibitor 1 K08886|1|1e-40|171|aam:106498025|activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0009898//cytoplasmic side of plasma membrane GO:0019900//kinase binding GO:0030324//lung development;GO:0001944//vasculature development;GO:0001933//negative regulation of protein phosphorylation;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0043588//skin development;GO:0030216//keratinocyte differentiation gi|19526962|ref|NP_598514.1|/0/ERBB receptor feedback inhibitor 1 [Mus musculus] 56279 1636 13.84333333 17.72666667 0.356729905 Up 0.537919816 Fam69b "family with sequence similarity 69, member B" K20242|1|4e-36|155|clv:102095124|ecotropic viral integration site 5 protein;K18660|2|6e-09|65.1|isc:IscW_ISCW011807|malonyl-CoA/methylmalonyl-CoA synthetase [EC:6.2.1.-];K02989|3|3e-06|56.2|bfo:BRAFLDRAFT_124722|small subunit ribosomal protein S5e GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|157951594|ref|NP_062807.2|/0/protein FAM69B precursor [Mus musculus] 13036 1630 25.16666667 31.47 0.322463035 Up 0.537872805 Ctsh cathepsin H K01366|1|0.0|697|mmu:13036|cathepsin H [EC:3.4.22.16] - - - - 50530 1413 26.99 21.53 -0.326076657 Down 0.537854 Mfap5 microfibrillar associated protein 5 K10989|1|5e-28|128|tgu:100229705|activation-induced cytidine deaminase [EC:3.5.4.38];K13526|2|1e-15|87.0|pps:100993572|cation-transporting ATPase 13A2 [EC:3.6.3.-] GO:0031012//extracellular matrix GO:0005201//extracellular matrix structural constituent GO:0030198//extracellular matrix organization gi|7657329|ref|NP_056591.1|/9.84026e-92/microfibrillar-associated protein 5 precursor [Mus musculus] 102693 5486 41.17666667 33.19666667 -0.31078866 Down 0.537741171 Phldb1 "pleckstrin homology like domain, family B, member 1" K09486|1|6e-174|615|asn:102367994|hypoxia up-regulated 1;K17916|2|4e-21|107|hmg:100212235|kinesin family member 16B - GO:0008289//lipid binding - gi|568958679|ref|XP_006509989.1|/0/PREDICTED: pleckstrin homology-like domain family B member 1 isoform X19 [Mus musculus] 54324 5420 7.59 5.453333333 -0.476961543 Down 0.537665952 Arhgef5 Rho guanine nucleotide exchange factor (GEF) 5 K07525|1|4e-109|399|lcm:102364542|neuronal guanine nucleotide exchange factor - - - gi|169234803|ref|NP_598435.1|/0/rho guanine nucleotide exchange factor 5 [Mus musculus] 208104 7321 14.49666667 11.16333333 -0.376953333 Down 0.53742149 Mlxip MLX interacting protein K09113|1|0.0|855|mmu:208104|MAX-like protein X GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0016020//membrane GO:0005515//protein binding;GO:0005515//protein binding "GO:0051169//nuclear transport;GO:0006351//transcription, DNA-templated;GO:0051169//nuclear transport;GO:0006351//transcription, DNA-templated" gi|188497661|ref|NP_598678.2|/0/MLX-interacting protein isoform 2 [Mus musculus] 56695 1434.93 88.08666667 71.85333333 -0.293868575 Down 0.537346271 Pnkd paroxysmal nonkinesiogenic dyskinesia "K05758|1|4e-14|80.1|asn:102388556|actin related protein 2/3 complex, subunit 2" GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding;GO:0016790//thiolester hydrolase activity GO:0006749//glutathione metabolic process;GO:0006749//glutathione metabolic process gi|9910442|ref|NP_064383.1|/0/probable hydrolase PNKD isoform 1 [Mus musculus] 72774 1170 4.836666667 3.196666667 -0.597444799 Down 0.537064199 Neil1 nei endonuclease VIII-like 1 (E. coli) K10567|1|0.0|800|mmu:72774|endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18] GO:0043231//intracellular membrane-bounded organelle;GO:0043232 "GO:0016835//carbon-oxygen lyase activity;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0004518//nuclease activity" GO:0006281//DNA repair;GO:0032069 gi|22094129|ref|NP_082623.1|/0/endonuclease 8-like 1 [Mus musculus] 73326 690 6.85 4.84 -0.501096941 Down 0.537017188 4932702P03Rik RIKEN cDNA 4932702P03 gene K00139|1|5e-27|123|cfa:488246|succinate-semialdehyde dehydrogenase [EC:1.2.1.24] - - - - 110695 3084.5 12.29666667 15.85333333 0.366518926 Up 0.536932566 Aldh7a1 "aldehyde dehydrogenase family 7, member A1" K14085|1|0.0|1096|mmu:110695|aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3] GO:0044429;GO:0044429 GO:0005488//binding;GO:0004029//aldehyde dehydrogenase (NAD) activity;GO:0005488//binding;GO:0004029//aldehyde dehydrogenase (NAD) activity GO:0050954//sensory perception of mechanical stimulus;GO:0006553//lysine metabolic process;GO:0019695//choline metabolic process;GO:0050954//sensory perception of mechanical stimulus;GO:0006553//lysine metabolic process;GO:0019695//choline metabolic process gi|188219757|ref|NP_613066.2|/0/alpha-aminoadipic semialdehyde dehydrogenase isoform a [Mus musculus] 433367 1751 52.65 42.78666667 -0.299272242 Down 0.536330813 Gm5532 predicted gene 5532 K08462|1|5e-09|43.5|mmu:70693|G protein-coupled receptor 125 - - - - 100504309 325 10.80333333 14.08666667 0.382853747 Up 0.536189778 Toporsos "topoisomerase I binding, arginine/serine-rich, opposite strand" - - - - - 236082 2211 8.47 11.27 0.412053641 Up 0.535973523 Dhrsx dehydrogenase/reductase (SDR family) X chromosome K11170|1|9e-165|583|mmu:236082|dehydrogenase/reductase SDR family member X [EC:1.1.-.-] - GO:0003824//catalytic activity GO:0044710 gi|124244062|ref|NP_001028498.2|/7.73911e-164/dehydrogenase/reductase SDR family member on chromosome X homolog precursor [Mus musculus] 70435 4618 17.03666667 13.26 -0.361562315 Down 0.535898304 Inf2 "inverted formin, FH2 and WH2 domain containing" K01939|1|2e-111|407|asn:102372125|adenylosuccinate synthase [EC:6.3.4.4];K05741|2|2e-42|178|aqu:100641591|diaphanous 2;K05745|4|2e-40|171|myb:102260421|diaphanous 3 GO:0044444//cytoplasmic part GO:0017016//Ras GTPase binding GO:0007010//cytoskeleton organization gi|568980383|ref|XP_006516288.1|/0/PREDICTED: inverted formin-2 isoform X2 [Mus musculus] 68818 1210.49 6.34 8.66 0.449884185 Up 0.535832487 Zfand2b "zinc finger, AN1 type domain 2B" - - GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding - gi|578803715|ref|XP_006712348.1|/2.3358e-108/PREDICTED: AN1-type zinc finger protein 2B isoform X1 [Homo sapiens] 71780 1850 15.29333333 19.44 0.346125328 Up 0.535785475 Isyna1 myo-inositol 1-phosphate synthase A1 K01858|1|0.0|1097|mmu:71780|myo-inositol-1-phosphate synthase [EC:5.5.1.4] GO:0044424 GO:0016872//intramolecular lyase activity GO:0006644//phospholipid metabolic process;GO:0006020//inositol metabolic process gi|12963757|ref|NP_076116.1|/0/inositol-3-phosphate synthase 1 [Mus musculus] 101861 3260 20.35333333 25.58 0.329751175 Up 0.535747866 Ints4 integrator complex subunit 4 K13141|1|0.0|1878|mmu:101861|integrator complex subunit 4 "GO:0016591//DNA-directed RNA polymerase II, holoenzyme" - GO:0016073//snRNA metabolic process gi|30794414|ref|NP_081532.1|/0/integrator complex subunit 4 [Mus musculus] 239691 1375 9.616666667 7.116666667 -0.434335249 Down 0.535691451 AU021092 expressed sequence AU021092 - - - - gi|268838809|ref|NP_001028392.2|/0/UPF0764 protein C16orf89 homolog precursor [Mus musculus] 22228 1583 168.3266667 204.14 0.278295148 Up 0.535672647 Ucp2 "uncoupling protein 2 (mitochondrial, proton carrier)" "K15103|1|3e-173|610|mmu:22228|solute carrier family 25 (mitochondrial uncoupling protein), member 8/9" GO:0031224//intrinsic component of membrane;GO:0005740//mitochondrial envelope;GO:0019866//organelle inner membrane - GO:0044703;GO:0032868//response to insulin;GO:0031100//organ regeneration;GO:0006915//apoptotic process;GO:0033993//response to lipid;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0009267//cellular response to starvation gi|344252924|gb|EGW09028.1|/1.36109e-179/Mitochondrial uncoupling protein 2 [Cricetulus griseus] 11870 1417 164.96 200.6066667 0.282253313 Up 0.535663244 Art1 ADP-ribosyltransferase 1 K06716|1|1e-173|612|mmu:11870|ADP-ribosyltransferase 1 [EC:2.4.2.31] GO:0031224//intrinsic component of membrane;GO:0005783//endoplasmic reticulum "GO:0016763//transferase activity, transferring pentosyl groups" GO:0006486//protein glycosylation gi|21687250|ref|NP_033840.2|/8.72294e-173/GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 precursor [Mus musculus] 69065 1583 8.486666667 11.27333333 0.409644241 Up 0.535635037 Chac1 "ChaC, cation transport regulator 1" K07232|1|5e-129|463|fca:101085130|cation transport protein ChaC GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005102//receptor binding GO:0034976//response to endoplasmic reticulum stress;GO:0007219//Notch signaling pathway;GO:0007399//nervous system development;GO:0016485//protein processing;GO:0035966//response to topologically incorrect protein gi|586989396|ref|XP_006932734.1|/4.4739e-128/PREDICTED: LOW QUALITY PROTEIN: glutathione-specific gamma-glutamylcyclotransferase 1 [Felis catus] 24110 1778 3.803333333 5.586666667 0.554723357 Up 0.535296551 Usp18 ubiquitin specific peptidase 18 K11846|1|0.0|733|mmu:24110|ubiquitin carboxyl-terminal hydrolase 18/41 [EC:3.4.19.12] - GO:0019783//ubiquitin-like protein-specific protease activity;GO:0016790//thiolester hydrolase activity GO:0019941//modification-dependent protein catabolic process;GO:0006464//cellular protein modification process;GO:0080184//response to phenylpropanoid gi|188035917|ref|NP_036039.2|/0/ubl carboxyl-terminal hydrolase 18 [Mus musculus] 216991 1611 7.08 5.05 -0.487465972 Down 0.535117906 Adap2 ArfGAP with dual PH domains 2 "K12486|1|2e-19|100|bfo:BRAFLDRAFT_141545|stromal membrane-associated protein;K12491|2|1e-18|97.4|hro:HELRODRAFT_110061|Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3" GO:0016020//membrane;GO:0031967;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0035091//phosphatidylinositol binding;GO:0043168//anion binding GO:0032012//regulation of ARF protein signal transduction;GO:0044767//single-organism developmental process;GO:0035556//intracellular signal transduction gi|26006859|ref|NP_742145.1|/0/arf-GAP with dual PH domain-containing protein 2 [Mus musculus] 14710 582.14 15.13333333 19.24333333 0.346628928 Up 0.535099101 Gngt2 "guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2" K04549|1|4e-32|139|mmu:14710|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0017111//nucleoside-triphosphatase activity;GO:0060089 GO:0009154//purine ribonucleotide catabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0009154//purine ribonucleotide catabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0009154//purine ribonucleotide catabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0009154//purine ribonucleotide catabolic process;GO:0007166//cell surface receptor signaling pathway "gi|148684052|gb|EDL15999.1|/1.73112e-32/guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2, isoform CRA_b [Mus musculus]" 67360 1047 8.17 5.946666667 -0.458254869 Down 0.534967468 1700095B10Rik RIKEN cDNA 1700095B10 gene K10362|1|5e-30|134|cge:100773043|myosin XVIII - - - - 75387 1553 7.066666667 9.55 0.434470874 Up 0.534901651 Sirt4 sirtuin 4 K11414|1|0.0|690|mmu:75387|NAD-dependent deacetylase sirtuin 4 [EC:3.5.1.-] GO:0044429;GO:0044429 "GO:0043169//cation binding;GO:0043168//anion binding;GO:0016763//transferase activity, transferring pentosyl groups;GO:0043169//cation binding;GO:0043168//anion binding;GO:0016763//transferase activity, transferring pentosyl groups" GO:0050796//regulation of insulin secretion;GO:0050796//regulation of insulin secretion "gi|18490478|gb|AAH22653.1|/0/Sirt4 protein, partial [Mus musculus]" 319154 502 0.536666667 0.01 -5.745954377 Down 0.534845237 Hist2h3b "histone cluster 2, H3b" K11253|1|5e-75|281|cge:100757491|histone H3 GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0016458//gene silencing;GO:0034728//nucleosome organization gi|625265376|ref|XP_007624151.1|/3.20774e-74/PREDICTED: uncharacterized protein LOC100757491 isoform X2 [Cricetulus griseus] 72240 518 0.01 0.54 5.754887502 Up 0.534845237 1600014C23Rik RIKEN cDNA 1600014C23 gene - - - - gi|332205952|ref|NP_082440.1|/1.65451e-55/uncharacterized protein LOC72240 [Mus musculus] 102465185 126 0.543333333 0.01 -5.763765654 Down 0.534845237 Mir6360 microRNA 6360 - - - - - 56717 8612 11.94666667 9.08 -0.395843934 Down 0.534553763 Mtor mechanistic target of rapamycin (serine/threonine kinase) K07203|1|0.0|4666|mmu:56717|serine/threonine-protein kinase mTOR [EC:2.7.11.1] GO:0031966//mitochondrial membrane;GO:0043234//protein complex;GO:0016604//nuclear body;GO:0012505//endomembrane system;GO:0043005//neuron projection;GO:0044297//cell body;GO:0000323//lytic vacuole GO:0001025//RNA polymerase III transcription factor binding;GO:0043021//ribonucleoprotein complex binding;GO:0001016//RNA polymerase III regulatory region DNA binding;GO:0004672//protein kinase activity;GO:0032550 GO:0010591//regulation of lamellipodium assembly;GO:0001934//positive regulation of protein phosphorylation;GO:0032094//response to food;GO:0048017//inositol lipid-mediated signaling;GO:0005978//glycogen biosynthetic process;GO:0010507//negative regulation of autophagy;GO:0038127//ERBB signaling pathway;GO:0009758//carbohydrate utilization;GO:0043434//response to peptide hormone;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0030041//actin filament polymerization;GO:0003006//developmental process involved in reproduction;GO:0032233//positive regulation of actin filament bundle assembly;GO:0008610//lipid biosynthetic process;GO:0001666//response to hypoxia;GO:0006635//fatty acid beta-oxidation;GO:0006383//transcription from RNA polymerase III promoter;GO:0040007//growth;GO:0006412//translation;GO:0001101//response to acid chemical;GO:0001935//endothelial cell proliferation;GO:0010830//regulation of myotube differentiation;GO:0008361//regulation of cell size;GO:0031294//lymphocyte costimulation;GO:0009057//macromolecule catabolic process "gi|148682872|gb|EDL14819.1|/0/FK506 binding protein 12-rapamycin associated protein 1, isoform CRA_a, partial [Mus musculus]" 19216 2082 21.48 17.00333333 -0.337176393 Down 0.534525556 Ptger1 prostaglandin E receptor 1 (subtype EP1) K04258|1|6e-134|480|mmu:19216|prostaglandin E receptor 1 GO:0016021//integral component of membrane GO:0004955//prostaglandin receptor activity GO:0002237//response to molecule of bacterial origin;GO:0007165//signal transduction "gi|149037902|gb|EDL92262.1|/2.12533e-147/prostaglandin E receptor 1, isoform CRA_a [Rattus norvegicus]" 192176 8357.47 21.24 16.76666667 -0.341187867 Down 0.534328106 Flna "filamin, alpha" K04437|1|0.0|5182|rno:293860|filamin GO:0043234//protein complex;GO:0015629//actin cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0030425//dendrite;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0015629//actin cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0030425//dendrite;GO:0044444//cytoplasmic part GO:0060089;GO:0031628//opioid receptor binding;GO:0034987//immunoglobulin receptor binding;GO:0017048//Rho GTPase binding;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0003779//actin binding;GO:0031267//small GTPase binding;GO:0005102//receptor binding "GO:0007015//actin filament organization;GO:0007052//mitotic spindle organization;GO:0010927;GO:0072657//protein localization to membrane;GO:0009895;GO:0042307//positive regulation of protein import into nucleus;GO:0044092//negative regulation of molecular function;GO:0006366//transcription from RNA polymerase II promoter;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0016192//vesicle-mediated transport;GO:0032507//maintenance of protein location in cell;GO:0031647//regulation of protein stability;GO:0006351//transcription, DNA-templated;GO:0071822;GO:0050794//regulation of cellular process;GO:0006810//transport;GO:0030036//actin cytoskeleton organization;GO:0034613//cellular protein localization" "gi|148697891|gb|EDL29838.1|/0/mCG21234, isoform CRA_a, partial [Mus musculus]" 69386 435 16.87333333 21.32666667 0.337913485 Up 0.534008425 Hist1h4h "histone cluster 1, H4h" K11254|1|4e-41|168|cge:100755357|histone H4;K11253|2|8e-41|167|oaa:100089390|histone H3 - - - gi|444523279|gb|ELV13502.1|/6.52964e-42/histone H2B type 1-M [Tupaia chinensis] 18822 3268 59.45666667 72.46 0.285346222 Up 0.533820377 Plod1 "procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1" "K00473|1|0.0|1446|mmu:18822|procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 [EC:1.14.11.4]" GO:0005578//proteinaceous extracellular matrix;GO:0005789//endoplasmic reticulum membrane "GO:0019842//vitamin binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0033218//amide binding;GO:0070815//peptidyl-lysine 5-dioxygenase activity;GO:0005506//iron ion binding" GO:0009888//tissue development;GO:0018126//protein hydroxylation;GO:0044710;GO:0009725//response to hormone;GO:0006950//response to stress "gi|6755106|ref|NP_035252.1|/0/procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 precursor [Mus musculus]" 66156 3248.11 11.57 14.99333333 0.373932296 Up 0.533763963 Anapc11 anaphase promoting complex subunit 11 K03358|1|5e-51|206|pale:102881804|anaphase-promoting complex subunit 11 GO:0031981//nuclear lumen;GO:0000152//nuclear ubiquitin ligase complex;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0000152//nuclear ubiquitin ligase complex;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0000209//protein polyubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle gi|611993538|ref|XP_007482917.1|/4.74565e-51/PREDICTED: anaphase-promoting complex subunit 11 isoform X2 [Monodelphis domestica] 18636 1636 5.463333333 7.583333333 0.473050691 Up 0.533181015 Cfp complement factor properdin K15412|1|0.0|1021|mmu:18636|complement factor properdin - - - - 81703 1570.99 9.573333333 12.55 0.390594116 Up 0.532889541 Jdp2 Jun dimerization protein 2 K09033|1|2e-68|262|ngi:103747341|jun dimerization protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0043566//structure-specific DNA binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0016575//histone deacetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|149025210|gb|EDL81577.1|/3.55425e-61/Jun dimerization protein 2, isoform CRA_a [Rattus norvegicus]" 52401 3909 3.6 5.31 0.560714954 Up 0.532861334 D5Ertd615e "DNA segment, Chr 5, ERATO Doi 615, expressed" - - - - - 21355 2490 19.31333333 24.19333333 0.325012372 Up 0.532015119 Tap2 "transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)" "K05654|1|0.0|1096|mmu:21355|ATP-binding cassette, subfamily B (MDR/TAP), member 3" - - - gi|239915963|ref|NP_035660.3|/0/antigen peptide transporter 2 [Mus musculus] 76411 825 14.29666667 18.20666667 0.348787998 Up 0.5319399 Ift43 intraflagellar transport 43 K19675|1|5e-112|405|mmu:76411|intraflagellar transport protein 43 GO:0043232;GO:0030990//intraciliary transport particle;GO:0043232;GO:0030990//intraciliary transport particle - GO:0048858//cell projection morphogenesis;GO:0042073//intraciliary transport;GO:0048858//cell projection morphogenesis;GO:0042073//intraciliary transport gi|315434196|ref|NP_001186772.1|/3.97817e-111/intraflagellar transport protein 43 homolog isoform 1 [Mus musculus] 75695 2281 111.0566667 134.7033333 0.278489552 Up 0.53190229 Rilpl1 Rab interacting lysosomal protein-like 1 K20173|1|0.0|721|mmu:75695|RILP-like protein 1 GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0031981//nuclear lumen - GO:0010941//regulation of cell death gi|10946796|ref|NP_067405.1|/0/RILP-like protein 1 [Mus musculus] 791403 828 1950.03 2346.773333 0.267182185 Up 0.531695438 Mhrt myosin heavy chain associated RNA transcript K17751|1|5e-43|176|aml:100469933|myosin heavy chain 6/7;K10352|5|9e-35|149|apla:101798957|myosin heavy chain - - - gi|837803448|ref|XP_012782271.1|/7.20703e-44/PREDICTED: myosin-6 [Ochotona princeps] 57259 3994 36.9 45.38666667 0.29864772 Up 0.531695438 Tob2 "transducer of ERBB2, 2" K14443|1|4e-133|479|mmu:57259|protein Tob/BTG - GO:0008134//transcription factor binding GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0001503//ossification;GO:0010467//gene expression gi|28972806|dbj|BAC65819.1|/2.15558e-133/mKIAA1663 protein [Mus musculus] 235587 2962.88 27.86333333 22.35333333 -0.317877878 Down 0.531526195 Parp3 "poly (ADP-ribose) polymerase family, member 3" K10798|1|0.0|917|mmu:235587|poly [ADP-ribose] polymerase [EC:2.4.2.30] - - - - 215494 2369 6.853333333 9.253333333 0.433167303 Up 0.531450976 Pomgnt2 "protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2" "K18207|1|0.0|1065|mmu:215494|protein O-mannose beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.312]" - GO:0016740//transferase activity;GO:0016740//transferase activity;GO:0016740//transferase activity;GO:0016740//transferase activity - "gi|148677171|gb|EDL09118.1|/0/mCG141435, partial [Mus musculus]" 11749 2656.22 102.3366667 124.1766667 0.279070963 Up 0.530999662 Anxa6 annexin A6 K17094|1|0.0|1293|mmu:11749|annexin A6 - - - - 216739 2597.34 5.696666667 7.84 0.460735663 Up 0.530962052 Acsl6 acyl-CoA synthetase long-chain family member 6 K01897|1|0.0|1388|mmu:216739|long-chain acyl-CoA synthetase [EC:6.2.1.3] GO:0042579//microbody;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0044439;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0044439;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0044439 GO:0032550;GO:0015645//fatty acid ligase activity;GO:0042802//identical protein binding;GO:0032550;GO:0015645//fatty acid ligase activity;GO:0042802//identical protein binding;GO:0032550;GO:0015645//fatty acid ligase activity;GO:0042802//identical protein binding;GO:0032550;GO:0015645//fatty acid ligase activity;GO:0042802//identical protein binding GO:0010975//regulation of neuron projection development;GO:0010746;GO:0006631//fatty acid metabolic process;GO:0010866//regulation of triglyceride biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0032868//response to insulin;GO:0010975//regulation of neuron projection development;GO:0010746;GO:0006631//fatty acid metabolic process;GO:0009628//response to abiotic stimulus;GO:0010866//regulation of triglyceride biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0031667//response to nutrient levels;GO:0032868//response to insulin;GO:0010975//regulation of neuron projection development;GO:0010746;GO:0006631//fatty acid metabolic process;GO:0009628//response to abiotic stimulus;GO:0010866//regulation of triglyceride biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0031667//response to nutrient levels;GO:0032868//response to insulin;GO:0010975//regulation of neuron projection development;GO:0010746;GO:0006631//fatty acid metabolic process;GO:0009628//response to abiotic stimulus;GO:0010866//regulation of triglyceride biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0031667//response to nutrient levels gi|75992913|ref|NP_001028769.1|/0/long-chain-fatty-acid--CoA ligase 6 isoform 2 [Mus musculus] 17926 2093 1.736666667 2.993333333 0.785432072 Up 0.530548347 Myoc myocilin K04593|1|6e-49|198|bfo:BRAFLDRAFT_86900|latrophilin 2 - - - - 67455 3275.37 3.81 5.546666667 0.54183003 Up 0.530341495 Klhl13 kelch-like 13 K10447|1|0.0|1273|mmu:67455|kelch-like protein 9/13 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex GO:0019787//ubiquitin-like protein transferase activity;GO:0019787//ubiquitin-like protein transferase activity GO:0032446//protein modification by small protein conjugation;GO:0000087//mitotic M phase;GO:0032446//protein modification by small protein conjugation;GO:0000087//mitotic M phase gi|28972714|dbj|BAC65773.1|/0/mKIAA1309 protein [Mus musculus] 72322 3709 9.81 7.336666667 -0.419128397 Down 0.530275678 Xpo5 exportin 5 K14289|1|0.0|2325|mmu:72322|exportin-5 GO:0005635//nuclear envelope GO:0003676//nucleic acid binding;GO:0022892//substrate-specific transporter activity GO:0016458//gene silencing;GO:0006886//intracellular protein transport gi|24429570|ref|NP_082474.1|/0/exportin-5 [Mus musculus] 12870 4244.19 21.38666667 26.73666667 0.322107971 Up 0.530068825 Cp ceruloplasmin K13624|1|0.0|2209|mmu:12870|ceruloplasmin [EC:1.16.3.1] GO:0031225//anchored component of membrane;GO:0044421;GO:0031225//anchored component of membrane;GO:0044421;GO:0031225//anchored component of membrane;GO:0044421 GO:0046914//transition metal ion binding;GO:0016724;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0016724;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0016724;GO:0005515//protein binding GO:0035434//copper ion transmembrane transport;GO:0030323//respiratory tube development;GO:0010038//response to metal ion;GO:0044710;GO:0031667//response to nutrient levels;GO:0006875//cellular metal ion homeostasis;GO:0035434//copper ion transmembrane transport;GO:0030323//respiratory tube development;GO:0010038//response to metal ion;GO:0044710;GO:0031667//response to nutrient levels;GO:0006875//cellular metal ion homeostasis;GO:0035434//copper ion transmembrane transport;GO:0030323//respiratory tube development;GO:0010038//response to metal ion;GO:0044710;GO:0031667//response to nutrient levels;GO:0006875//cellular metal ion homeostasis "gi|148702938|gb|EDL34885.1|/0/ceruloplasmin, isoform CRA_c, partial [Mus musculus]" 319182 522 0.136666667 0.833333333 2.60823228 Up 0.529720937 Hist1h2bh "histone cluster 1, H2bh" K11252|1|1e-44|180|bacu:103017256|histone H2B GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|826334649|ref|XP_012514231.1|/3.91637e-44/PREDICTED: histone H2B type 2-F-like [Propithecus coquereli] 20306 912 0.49 1.38 1.493814613 Up 0.529720937 Ccl7 chemokine (C-C motif) ligand 7 K05509|1|2e-43|178|mmu:20306|C-C motif chemokine 7 GO:0044421 GO:0005125//cytokine activity;GO:0048020//CCR chemokine receptor binding;GO:0005539//glycosaminoglycan binding GO:0006952//defense response;GO:0006996//organelle organization;GO:0010212//response to ionizing radiation;GO:0022604//regulation of cell morphogenesis;GO:0045471//response to ethanol;GO:0002690//positive regulation of leukocyte chemotaxis gi|7305463|ref|NP_038682.1|/1.25319e-42/C-C motif chemokine 7 precursor [Mus musculus] 53412 2696 110.48 90.78 -0.283338831 Down 0.529702132 Ppp1r3c "protein phosphatase 1, regulatory (inhibitor) subunit 3C" K07189|1|8e-179|630|mmu:53412|protein phosphatase 1 regulatory subunit 3A/B/C/D/E GO:0043227//membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0016791//phosphatase activity;GO:0019902//phosphatase binding GO:0005980//glycogen catabolic process;GO:0006886//intracellular protein transport;GO:0005978//glycogen biosynthetic process gi|33468957|ref|NP_058550.1|/6.98937e-178/protein phosphatase 1 regulatory subunit 3C [Mus musculus] 69379 847.13 1.13 2.236666667 0.985027493 Up 0.529589304 C8g "complement component 8, gamma polypeptide" K03999|1|6e-100|366|mmu:69379|complement component 8 subunit gamma GO:0044421;GO:0005887//integral component of plasma membrane;GO:0044421;GO:0005887//integral component of plasma membrane GO:0005501//retinoid binding;GO:0005515//protein binding;GO:0005501//retinoid binding;GO:0005515//protein binding GO:0006952//defense response;GO:0006956//complement activation;GO:0008219//cell death;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0006952//defense response;GO:0006956//complement activation;GO:0008219//cell death;GO:0002455//humoral immune response mediated by circulating immunoglobulin gi|58037159|ref|NP_081338.1|/5.27538e-99/complement component C8 gamma chain isoform 1 precursor [Mus musculus] 107022 2611 7.863333333 10.47666667 0.413966854 Up 0.529241416 Gramd3 GRAM domain containing 3 K19951|1|1e-08|64.7|lcm:102359840|TBC1 domain family member 9 GO:0005874//microtubule - - gi|12858310|dbj|BAB31270.1|/0/unnamed protein product [Mus musculus] 73680 2229 1.34 2.496666667 0.897770217 Up 0.529109782 Zbtb8a zinc finger and BTB domain containing 8a K10495|1|0.0|870|mmu:73680|zinc finger and BTB domain-containing protein 8 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" "gi|148698251|gb|EDL30198.1|/0/RIKEN cDNA 2410081M15, isoform CRA_a, partial [Mus musculus]" 12040 1445.17 46.53333333 57.04666667 0.293878054 Up 0.528940539 Bckdhb "branched chain ketoacid dehydrogenase E1, beta polypeptide" K00167|1|1e-179|632|rno:29711|2-oxoisovalerate dehydrogenase E1 component beta subunit [EC:1.2.4.4] GO:0043231//intracellular membrane-bounded organelle;GO:0045240;GO:0019866//organelle inner membrane "GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0005515//protein binding" GO:0046683//response to organophosphorus;GO:0031667//response to nutrient levels;GO:0031960//response to corticosteroid;GO:0009063//cellular amino acid catabolic process "gi|806776659|ref|NP_001292864.1|/0/2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform 1 [Mus musculus]" 101056138 1033.96 2.45 3.88 0.663274903 Up 0.528893527 Gm20619 predicted gene 20619 - - - - - 66330 931 3.203333333 4.78 0.577436688 Up 0.528827711 1700020L24Rik RIKEN cDNA 1700020L24 gene - - - - - 67605 1660 47.45333333 57.83 0.28530867 Up 0.528686675 Akt1s1 AKT1 substrate 1 (proline-rich) K16184|1|4e-74|281|mmu:67605|proline-rich AKT1 substrate 1 GO:0005829//cytosol;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032991//macromolecular complex - GO:0042981//regulation of apoptotic process;GO:0007165//signal transduction;GO:0042981//regulation of apoptotic process;GO:0007165//signal transduction;GO:0048523//negative regulation of cellular process;GO:0007165//signal transduction;GO:0009968//negative regulation of signal transduction;GO:0001933//negative regulation of protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008361//regulation of cell size;GO:0042981//regulation of apoptotic process gi|568948348|ref|XP_006541178.1|/3.65418e-101/PREDICTED: proline-rich AKT1 substrate 1 isoform X2 [Mus musculus] 24052 1399 5.233333333 7.273333333 0.474886543 Up 0.528611456 Sgcd "sarcoglycan, delta (dystrophin-associated glycoprotein)" K12563|1|6e-152|539|mmu:24052|delta-sarcoglycan GO:0043232;GO:0016011//dystroglycan complex;GO:0016021//integral component of membrane - GO:0006996//organelle organization gi|6755484|ref|NP_036021.1|/5.41721e-151/delta-sarcoglycan [Mus musculus] 109620 9592 102.5466667 84.51333333 -0.279029724 Down 0.528602053 Dsp desmoplakin K10381|1|0.0|5019|mmu:109620|desmoplakin - - - - 52055 5668.7 40.54333333 32.90666667 -0.301084813 Down 0.528461018 Rab11fip5 RAB11 family interacting protein 5 (class I) K12484|1|0.0|1108|mmu:52055|Rab11 family-interacting protein 1/2/5 GO:0005815//microtubule organizing center;GO:0010008//endosome membrane;GO:0031966//mitochondrial membrane GO:0015631//tubulin binding GO:0045184//establishment of protein localization gi|55743143|ref|NP_803417.3|/0/rab11 family-interacting protein 5 isoform 2 [Mus musculus] 226519 7622 32.35 26.08 -0.310821843 Down 0.528442213 Lamc1 "laminin, gamma 1" "K05635|1|0.0|3070|mmu:226519|laminin, gamma 1" GO:0031988//membrane-bounded vesicle;GO:0043256//laminin complex GO:0046625//sphingolipid binding GO:0022610;GO:0030030//cell projection organization;GO:0048870//cell motility;GO:0022411;GO:0007044//cell-substrate junction assembly;GO:0065003;GO:0000904//cell morphogenesis involved in differentiation "gi|148707495|gb|EDL39442.1|/0/laminin, gamma 1, isoform CRA_b, partial [Mus musculus]" 15893 1862.12 6.69 9.013333333 0.430054535 Up 0.527784046 Ica1 islet cell autoantigen 1 K19863|1|0.0|971|mmu:15893|islet cell auto antigen 1 GO:0030141//secretory granule;GO:0043005//neuron projection;GO:0031981//nuclear lumen;GO:0030133//transport vesicle;GO:0008021//synaptic vesicle;GO:0012505//endomembrane system;GO:0044431//Golgi apparatus part;GO:0030141//secretory granule;GO:0043005//neuron projection;GO:0031981//nuclear lumen;GO:0030133//transport vesicle;GO:0008021//synaptic vesicle;GO:0012505//endomembrane system;GO:0044431//Golgi apparatus part GO:0005515//protein binding;GO:0005515//protein binding GO:0043393//regulation of protein binding;GO:0007269//neurotransmitter secretion;GO:0043393//regulation of protein binding;GO:0007269//neurotransmitter secretion gi|356582438|ref|NP_001239195.1|/0/islet cell autoantigen 1 isoform 2 [Mus musculus] 230726 1217 1.583333333 2.79 0.817300109 Up 0.527765241 Rhbdl2 "rhomboid, veinlet-like 2 (Drosophila)" K02857|1|7e-144|512|mmu:230726|rhomboid-related protein 1/2/3 [EC:3.4.21.105] GO:0031224//intrinsic component of membrane GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|126723321|ref|NP_898986.2|/5.81537e-143/rhomboid-related protein 2 [Mus musculus] 105722 5670.38 11.13333333 8.46 -0.396156034 Down 0.527624205 Ano6 anoctamin 6 K19500|1|0.0|1726|mmu:105722|anoctamin-6 GO:0044464;GO:0034702//ion channel complex;GO:0044464;GO:0034702//ion channel complex GO:0005261//cation channel activity;GO:0005254//chloride channel activity;GO:0005261//cation channel activity;GO:0005254//chloride channel activity GO:0017121//phospholipid scrambling;GO:0015698//inorganic anion transport;GO:0007599//hemostasis;GO:0034220//ion transmembrane transport;GO:0017121//phospholipid scrambling;GO:0015698//inorganic anion transport;GO:0007599//hemostasis;GO:0034220//ion transmembrane transport gi|359465539|ref|NP_001240742.1|/0/anoctamin-6 isoform 1 [Mus musculus] 237754 2463 7.66 5.58 -0.45707927 Down 0.527473767 Btnl9 butyrophilin-like 9 K06712|1|0.0|1097|mmu:237754|butyrophilin GO:0031224//intrinsic component of membrane - - "gi|148701824|gb|EDL33771.1|/0/RIKEN cDNA D330012D11, isoform CRA_c, partial [Mus musculus]" 19183 984 8.423333333 6.196666667 -0.442898894 Down 0.527454963 Psmc3ip "proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein" "K06695|1|1e-120|434|mmu:19183|26S proteasome regulatory subunit, ATPase 3, interacting protein" GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0035258//steroid hormone receptor binding;GO:0019904//protein domain specific binding;GO:0008134//transcription factor binding;GO:0003713//transcription coactivator activity GO:0006259//DNA metabolic process;GO:0022403;GO:0006366//transcription from RNA polymerase II promoter gi|25092696|ref|NP_032975.1|/1.0982e-119/homologous-pairing protein 2 homolog [Mus musculus] 76293 1513 25.4 20.31666667 -0.322164777 Down 0.527426755 Mfap4 microfibrillar-associated protein 4 K10104|1|1e-57|226|ggo:101130418|ficolin GO:0031012//extracellular matrix - GO:0022610 gi|21313152|ref|NP_083844.1|/9.07725e-139/microfibril-associated glycoprotein 4 precursor [Mus musculus] 12583 1530 3.14 4.696666667 0.580872647 Up 0.527238708 Cdo1 "cysteine dioxygenase 1, cytosolic" K00456|1|1e-115|419|rno:81718|cysteine dioxygenase [EC:1.13.11.20] GO:0044444//cytoplasmic part "GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0005506//iron ion binding" GO:0019448//L-cysteine catabolic process;GO:0001101//response to acid chemical;GO:0097305//response to alcohol;GO:0046683//response to organophosphorus;GO:0019530//taurine metabolic process;GO:0043434//response to peptide hormone;GO:0007589//body fluid secretion;GO:0031960//response to corticosteroid gi|14719434|ref|NP_149026.1|/9.21771e-115/cysteine dioxygenase type 1 [Mus musculus] 23957 1282 8.21 10.86 0.403569976 Up 0.527031855 Nr0b2 "nuclear receptor subfamily 0, group B, member 2" K08563|1|3e-151|537|mmu:23957|nuclear receptor subfamily 0 group B member 2 - - - - 76482 2134 14.74 18.72 0.34484391 Up 0.526843808 3110002H16Rik RIKEN cDNA 3110002H16 gene - - - - - 194231 2467 11.77333333 9.013333333 -0.385390191 Down 0.526401896 Cnksr1 connector enhancer of kinase suppressor of Ras 1 K17536|1|9e-65|251|cmk:103179536|connector enhancer of kinase suppressor of Ras 2 GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0008289//lipid binding GO:0007265//Ras protein signal transduction gi|124486674|ref|NP_001074516.1|/0/connector enhancer of kinase suppressor of ras 1 [Mus musculus] 108841 3007.64 11.69 8.94 -0.386928193 Down 0.5260258 Rdh13 retinol dehydrogenase 13 (all-trans and 9-cis) K11161|1|1e-147|526|mmu:108841|retinol dehydrogenase 13 [EC:1.1.1.300] GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity GO:0044710 gi|30425078|ref|NP_780581.1|/2.42216e-174/retinol dehydrogenase 13 isoform 1 precursor [Mus musculus] 320078 3105 8.77 11.52 0.393491969 Up 0.5260258 Olfml2b olfactomedin-like 2B K04592|1|2e-48|197|gja:107116182|latrophilin 1 - - - gi|74208871|dbj|BAE21187.1|/0/unnamed protein product [Mus musculus] 56358 937 30.94666667 37.99666667 0.296088839 Up 0.525612095 Copz2 "coatomer protein complex, subunit zeta 2" K20472|1|2e-98|360|mmu:56358|coatomer subunit zeta GO:0005798//Golgi-associated vesicle;GO:0030120//vesicle coat - GO:0015031//protein transport gi|9845242|ref|NP_063930.1|/1.86785e-97/coatomer subunit zeta-2 [Mus musculus] 66548 3487.99 50.36666667 41.13666667 -0.292044359 Down 0.525555681 Adamtsl5 ADAMTS-like 5 K15686|1|2e-78|296|bta:100337439|RNA-binding protein MEX3 [EC:2.3.2.27];K08625|2|8e-47|191|mze:101466052|a disintegrin and metalloproteinase with thrombospondin motifs 10 [EC:3.4.24.-] - - - "gi|148699613|gb|EDL31560.1|/0/ADAMTS-like 5, isoform CRA_d, partial [Mus musculus]" 547349 1187 2.363333333 1.246666667 -0.922747357 Down 0.525254805 LOC547349 MHC class I family member "K06751|1|0.0|759|mmu:547349|major histocompatibility complex, class I" GO:0031224//intrinsic component of membrane;GO:0044464 - GO:0045953//negative regulation of natural killer cell mediated cytotoxicity gi|68534959|ref|NP_001020379.1|/0/MHC class I family member precursor [Mus musculus] 100503496 1776 4.2 2.733333333 -0.619727919 Down 0.525226597 LOC100503496 uncharacterized LOC100503496 "K08183|1|1e-35|154|mmu:104681|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 6" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0051234//establishment of localization;GO:0044763 gi|71067107|ref|NP_001025013.1|/8.83551e-35/monocarboxylate transporter 7 isoform a [Mus musculus] 14257 5853 11.50333333 8.79 -0.388116903 Down 0.524634247 Flt4 FMS-like tyrosine kinase 4 K05097|1|0.0|2744|mmu:14257|FMS-like tyrosine kinase 4 [EC:2.7.10.1] GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane GO:0032550;GO:0019902//phosphatase binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity GO:0001525//angiogenesis;GO:0010594//regulation of endothelial cell migration;GO:0071363//cellular response to growth factor stimulus;GO:0001935//endothelial cell proliferation;GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007254//JNK cascade;GO:0001819//positive regulation of cytokine production;GO:0001932//regulation of protein phosphorylation;GO:0016049//cell growth;GO:0043410//positive regulation of MAPK cascade;GO:0001974//blood vessel remodeling gi|6679813|ref|NP_032055.1|/0/vascular endothelial growth factor receptor 3 precursor [Mus musculus] 77613 3028 2.396666667 3.786666667 0.659899159 Up 0.52440859 Prss36 "protease, serine 36" K09630|1|0.0|1733|mmu:77613|polyserase 2 [EC:3.4.21.-] - - - gi|982725831|ref|NP_001306076.1|/0/polyserase-2 precursor [Mus musculus] 74153 3162 9.31 12.15666667 0.384894626 Up 0.524239347 Uba7 ubiquitin-like modifier activating enzyme 7 K10698|1|0.0|1972|mmu:74153|ubiquitin-activating enzyme E1-like [EC:6.2.1.45] - GO:0008641//small protein activating enzyme activity GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0006464//cellular protein modification process gi|30794156|ref|NP_076227.1|/0/ubiquitin-like modifier-activating enzyme 7 [Mus musculus] 13877 812 23.80333333 29.5 0.309551337 Up 0.524145323 Erh enhancer of rudimentary homolog (Drosophila) K06233|1|5e-09|63.9|cin:100183506|low density lipoprotein-related protein 2 GO:0044464 - GO:0044763;GO:0006952//defense response;GO:0009116//nucleoside metabolic process "gi|148670722|gb|EDL02669.1|/8.82932e-55/mCG7617, isoform CRA_a [Mus musculus]" 214305 2605 2.03 1.006666667 -1.011893679 Down 0.524088909 Hhipl1 hedgehog interacting protein-like 1 K15212|1|0.0|760|ssc:100517774|TATA box-binding protein-associated factor RNA polymerase I subunit A;K06231|2|2e-65|253|bfo:BRAFLDRAFT_117107|hedgehog interacting protein - "GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0048037//cofactor binding;GO:0038024//cargo receptor activity" GO:0044710;GO:0044238//primary metabolic process gi|124249064|ref|NP_001037845.1|/0/HHIP-like protein 1 precursor [Mus musculus] 16819 853 11.23333333 8.546666667 -0.394352329 Down 0.523900861 Lcn2 lipocalin 2 K01830|1|2e-24|115|mdo:100022407|prostaglandin-H2 D-isomerase [EC:5.3.99.2] GO:0044444//cytoplasmic part;GO:0044421 GO:0046914//transition metal ion binding;GO:0042802//identical protein binding GO:0034614//cellular response to reactive oxygen species;GO:0006952//defense response;GO:0015688//iron chelate transport;GO:0030030//cell projection organization;GO:0006915//apoptotic process;GO:0031667//response to nutrient levels;GO:0055080//cation homeostasis;GO:0051260//protein homooligomerization;GO:0034612//response to tumor necrosis factor;GO:0070555//response to interleukin-1;GO:0010467//gene expression;GO:0032496//response to lipopolysaccharide "gi|1019908|gb|AAA79309.1|/2.81635e-150/ORF, partial [Mus musculus]" 67119 1531 2.346666667 1.236666667 -0.924156242 Down 0.523769228 Ccdc159 coiled-coil domain containing 159 K19581|1|2e-24|116|asn:102379922|lipid phosphate phosphatase-related protein type 1/2/5 - - - "gi|148693284|gb|EDL25231.1|/0/RIKEN cDNA 2510048L02, isoform CRA_b, partial [Mus musculus]" 67399 1086.28 61.00666667 73.95333333 0.27764827 Up 0.523703411 Pdlim7 PDZ and LIM domain 7 K19867|1|6e-20|100|cjo:107315549|LIM domain-binding protein 3 - - - - 652925 988 8.666666667 11.35 0.389143175 Up 0.523609387 Tmem243 "transmembrane protein 243, mitochondrial" - GO:0031224//intrinsic component of membrane - - gi|124486626|ref|NP_001074498.1|/8.34179e-51/transmembrane protein 243 [Mus musculus] 72621 1015 16.54333333 20.78 0.3289457 Up 0.523487156 Pdzd11 PDZ domain containing 11 K19931|1|3e-11|71.6|spu:585083|protein lin-7 GO:0044459;GO:0044444//cytoplasmic part GO:0005515//protein binding - "gi|148682229|gb|EDL14176.1|/4.04553e-80/PDZ domain containing 11, isoform CRA_c, partial [Mus musculus]" 235534 2954 1.143333333 2.223333333 0.959478185 Up 0.523393132 Pxylp1 2-phosphoxylose phosphatase 1 "K15116|1|4e-28|129|spu:583160|solute carrier family 25, member 33/36;K14395|2|7e-17|92.4|xla:100127261|lysophosphatidic acid phosphatase type 6 [EC:3.1.3.2];K01078|3|2e-16|91.3|cbr:CBG06099|acid phosphatase [EC:3.1.3.2]" - GO:0016791//phosphatase activity;GO:0016791//phosphatase activity;GO:0016791//phosphatase activity;GO:0016791//phosphatase activity - gi|23510309|ref|NP_700469.1|/0/2-phosphoxylose phosphatase 1 [Mus musculus] 217038 2490 6.053333333 8.19 0.436133655 Up 0.523129866 Mrm1 mitochondrial rRNA methyltransferase 1 K15507|1|4e-157|558|mmu:217038|21S rRNA (GM2251-2'-O)-methyltransferase [EC:2.1.1.-] - - - "gi|148683794|gb|EDL15741.1|/1.16084e-179/mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae), partial [Mus musculus]" 14998 1658 1.82 3.066666667 0.75273291 Up 0.523054647 H2-DMa "histocompatibility 2, class II, locus DMa" "K06752|1|1e-145|518|mmu:14998|major histocompatibility complex, class II" GO:0005764//lysosome;GO:0005770//late endosome;GO:0042611;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane GO:0005488//binding GO:0002920//regulation of humoral immune response;GO:0002467//germinal center formation;GO:0043583//ear development;GO:0019724//B cell mediated immunity;GO:0043368//positive T cell selection;GO:0065003;GO:0045184//establishment of protein localization;GO:0002478;GO:0002684//positive regulation of immune system process;GO:0051084//'de novo' posttranslational protein folding "gi|148539979|ref|NP_034516.3|/1.24899e-144/class II histocompatibility antigen, M alpha chain precursor [Mus musculus]" 93714 4540 0.516666667 1.386666667 1.424315313 Up 0.522941818 Pcdhga6 "protocadherin gamma subfamily A, 6" K16495|1|0.0|1692|mmu:93714|protocadherin gamma subfamily A GO:0031224//intrinsic component of membrane - GO:0022610 gi|18087763|ref|NP_291067.1|/0/protocadherin gamma-A6 precursor [Mus musculus] 76257 2477.37 57.18 69.38 0.279009221 Up 0.522697356 Slc38a3 "solute carrier family 38, member 3" "K13576|1|0.0|944|mmu:76257|solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 3" GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity GO:0030001//metal ion transport;GO:0015807//L-amino acid transport;GO:0030001//metal ion transport;GO:0015807//L-amino acid transport;GO:0030001//metal ion transport;GO:0015807//L-amino acid transport gi|34328322|ref|NP_076294.2|/0/sodium-coupled neutral amino acid transporter 3 [Mus musculus] 18187 6439.46 9.796666667 7.38 -0.408670137 Down 0.522123811 Nrp2 neuropilin 2 K06819|1|0.0|1867|mmu:18187|neuropilin 2 GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection GO:0043169//cation binding;GO:0005539//glycosaminoglycan binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0043169//cation binding;GO:0005539//glycosaminoglycan binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0043169//cation binding;GO:0005539//glycosaminoglycan binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0043169//cation binding;GO:0005539//glycosaminoglycan binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0043169//cation binding;GO:0005539//glycosaminoglycan binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0043169//cation binding;GO:0005539//glycosaminoglycan binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity GO:0048869//cellular developmental process;GO:0048731//system development;GO:0022610;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0001667//ameboidal-type cell migration;GO:0006935//chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044767//single-organism developmental process;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0022610;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0001667//ameboidal-type cell migration;GO:0006935//chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044767//single-organism developmental process;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0022610;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0001667//ameboidal-type cell migration;GO:0006935//chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044767//single-organism developmental process;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0022610;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0001667//ameboidal-type cell migration;GO:0006935//chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044767//single-organism developmental process;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0022610;GO:0001667//ameboidal-type cell migration;GO:0006935//chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044767//single-organism developmental process;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0022610;GO:0001667//ameboidal-type cell migration;GO:0006935//chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044767//single-organism developmental process gi|116686142|ref|NP_001070873.1|/0/neuropilin-2 isoform 4 precursor [Mus musculus] 217410 4198 11.14333333 8.51 -0.388949817 Down 0.521869946 Trib2 tribbles pseudokinase 2 K08814|1|0.0|700|mmu:217410|tribbles homolog 1/2 GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0016301//kinase activity;GO:0032550;GO:0044389//ubiquitin-like protein ligase binding;GO:0055103//ligase regulator activity;GO:0019887//protein kinase regulator activity GO:0031398//positive regulation of protein ubiquitination;GO:0043408//regulation of MAPK cascade;GO:0045444//fat cell differentiation;GO:0001933//negative regulation of protein phosphorylation;GO:0044092//negative regulation of molecular function;GO:0031331;GO:0042036//negative regulation of cytokine biosynthetic process gi|31542100|ref|NP_653134.2|/0/tribbles homolog 2 [Mus musculus] 68981 1250 12.44666667 15.85333333 0.349026788 Up 0.521832337 Snrpa1 small nuclear ribonucleoprotein polypeptide A' K11092|1|1e-139|498|mmu:68981|U2 small nuclear ribonucleoprotein A' GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding GO:0000377 gi|880957181|ref|XP_005084478.2|/1.81315e-139/PREDICTED: U2 small nuclear ribonucleoprotein A' [Mesocricetus auratus] 228662 4778.62 4.73 3.183333333 -0.571301951 Down 0.52176652 Btbd3 BTB (POZ) domain containing 3 K10478|1|0.0|962|mmu:228662|BTB/POZ domain-containing protein 3/6 - - - gi|26006233|dbj|BAC41459.1|/0/mKIAA0952 protein [Mus musculus] 15039 1758 27.39666667 33.78333333 0.302311311 Up 0.521738313 H2-T22 "histocompatibility 2, T region locus 22" "K06751|1|0.0|724|mmu:15039|major histocompatibility complex, class I" - - GO:0043583//ear development "gi|148691329|gb|EDL23276.1|/0/mCG132391, isoform CRA_b [Mus musculus]" 99011 2838 6.286666667 8.476666667 0.431201786 Up 0.521691301 Pomt1 protein-O-mannosyltransferase 1 K00728|1|0.0|1375|mmu:99011|dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109] GO:0031224//intrinsic component of membrane;GO:0030141//secretory granule;GO:0031090//organelle membrane;GO:0005783//endoplasmic reticulum GO:0043169//cation binding;GO:0000030//mannosyltransferase activity GO:0043062//extracellular structure organization;GO:0006486//protein glycosylation gi|21553107|ref|NP_660127.1|/0/protein O-mannosyl-transferase 1 [Mus musculus] 238328 6189 9.693333333 7.28 -0.413054413 Down 0.521559668 Vash1 vasohibin 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0044421 - GO:0001525//angiogenesis;GO:0010596//negative regulation of endothelial cell migration;GO:0051093//negative regulation of developmental process;GO:0080135//regulation of cellular response to stress;GO:0001935//endothelial cell proliferation gi|148670956|gb|EDL02903.1|/0/vasohibin 1 [Mus musculus] 673094 950 105.5466667 127.1633333 0.268801723 Up 0.520685246 Cd99 CD99 antigen - - - - - 320717 4611 43.4 35.53333333 -0.28852201 Down 0.520628831 Pptc7 PTC7 protein phosphatase homolog K17508|1|1e-160|570|mmu:320717|protein phosphatase PTC7 [EC:3.1.3.16] - - - - 76281 1417 27.20333333 33.42666667 0.297216054 Up 0.5205066 Tax1bp3 Tax1 (human T cell leukemia virus type I) binding protein 3 K08876|1|3e-12|75.9|tsp:Tsp_08308|SCY1-like protein 1;K15682|2|7e-11|71.2|amj:102570820|ligand of Numb protein X 3/4 [EC:2.3.2.27];K16175|4|7e-10|67.8|tca:659629|protein scribble GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding GO:0016055//Wnt signaling pathway;GO:0008283//cell proliferation;GO:0048523//negative regulation of cellular process gi|21313140|ref|NP_083840.1|/1.25736e-62/tax1-binding protein 3 [Mus musculus] 17470 2363 17.69 22.14333333 0.323938366 Up 0.520130505 Cd200 CD200 antigen K06556|1|1e-148|530|mmu:17470|CD200 antigen GO:0031224//intrinsic component of membrane - - gi|26006825|sp|O54901.1|OX2G_MOUSE/8.45177e-148/RecName: Full=OX-2 membrane glycoprotein; AltName: Full=MRC OX-2 antigen; AltName: CD_antigen=CD200; Flags: Precursor 75956 8613 32.67666667 26.52333333 -0.300998724 Down 0.520055286 Srrm2 serine/arginine repetitive matrix 2 K13172|1|0.0|1234|mmu:75956|serine/arginine repetitive matrix protein 2 - - - gi|755559296|ref|XP_011245004.1|/0/PREDICTED: serine/arginine repetitive matrix protein 2 isoform X4 [Mus musculus] 14980 1077 41.86666667 34.23 -0.290540766 Down 0.519669788 H2-L "histocompatibility 2, D region locus L" "K06751|1|0.0|738|mmu:14980|major histocompatibility complex, class I" GO:0031224//intrinsic component of membrane;GO:0042611;GO:0009986//cell surface GO:0005515//protein binding GO:0002484;GO:0002664//regulation of T cell tolerance induction;GO:0009581;GO:0001817//regulation of cytokine production "gi|392357527|ref|NP_001254737.1|/0/histocompatibility 2, D region locus L [Mus musculus]" 319899 6577 16.98 13.38666667 -0.34303969 Down 0.51955696 Dock6 dedicator of cytokinesis 6 K13708|1|5e-15|87.4|crg:105338650|dedicator of cytokinesis protein 1;K05727|3|3e-12|78.2|nvi:100118634|dedicator of cytokinesis protein 3 - - - gi|124301208|ref|NP_796004.2|/0/dedicator of cytokinesis protein 6 [Mus musculus] 54445 2277 10.79666667 13.85666667 0.35999428 Up 0.519472338 Unc93b1 unc-93 homolog B1 (C. elegans) K16600|1|1e-19|101|gga:421566|tubulin polyglutamylase TTLL2 [EC:6.-.-.-] GO:0000323//lytic vacuole;GO:0045335//phagocytic vesicle;GO:0000323//lytic vacuole;GO:0045335//phagocytic vesicle GO:0005102//receptor binding;GO:0005102//receptor binding GO:0002478;GO:0002224//toll-like receptor signaling pathway;GO:0015031//protein transport;GO:0002478;GO:0002224//toll-like receptor signaling pathway;GO:0015031//protein transport gi|238637324|ref|NP_001154900.1|/0/protein unc-93 homolog B1 isoform b [Mus musculus] 20201 392 2.18 3.49 0.678898901 Up 0.519312498 S100a8 S100 calcium binding protein A8 (calgranulin A) K17274|1|1e-06|53.9|ola:101155699|calpactin-1 light chain GO:0043232;GO:0016020//membrane;GO:0044421 GO:0046872//metal ion binding GO:0012502//induction of programmed cell death;GO:0044248;GO:0010038//response to metal ion;GO:0097305//response to alcohol;GO:0006954//inflammatory response;GO:0006915//apoptotic process;GO:0070486//leukocyte aggregation;GO:0002237//response to molecule of bacterial origin;GO:0030595//leukocyte chemotaxis gi|7305453|ref|NP_038678.1|/6.3098e-45/protein S100-A8 [Mus musculus] 234072 1365 527.93 633.51 0.263020742 Up 0.519049231 Adprhl1 ADP-ribosylhydrolase like 1 K01245|1|8e-88|326|xla:495095|ADP-ribosylarginine hydrolase [EC:3.2.2.19] GO:0044464 "GO:0046872//metal ion binding;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds" GO:0006464//cellular protein modification process gi|27370110|ref|NP_766338.1|/0/[Protein ADP-ribosylarginine] hydrolase-like protein 1 [Mus musculus] 11520 1887 48.37333333 58.77666667 0.281031588 Up 0.518832976 Plin2 perilipin 2 K17284|1|0.0|792|mmu:11520|perilipin-2 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane - GO:0006629//lipid metabolic process;GO:0015908//fatty acid transport;GO:0010033//response to organic substance gi|116235489|ref|NP_031434.3|/0/perilipin-2 [Mus musculus] 50795 1321 109.02 90.71333333 -0.265206302 Down 0.518776562 Sh3bgr SH3-binding domain glutamic acid-rich protein "K03877|1|6e-53|210|tgu:100227439|beta-1,3-galactosyltransferase 5 [EC:2.4.1.-];K13912|2|6e-09|64.7|xma:102221819|deleted in malignant brain tumors 1 protein" - - - gi|166796515|gb|AAI59441.1|/2.14325e-85/Sh3bgr protein [Rattus norvegicus] 641454 1621.21 0.086666667 0.71 3.034269902 Up 0.518767159 5830444B04Rik RIKEN cDNA 5830444B04 gene - - - - gi|149024801|gb|EDL81298.1|/2.3186e-14/rCG31255 [Rattus norvegicus] 101023 2284.88 5.74 7.796666667 0.441806719 Up 0.518626124 Zfp513 zinc finger protein 513 K09228|1|1e-92|343|cmk:103178353|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0000975//regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0000975//regulatory region DNA binding "GO:0043010//camera-type eye development;GO:0006351//transcription, DNA-templated;GO:0043010//camera-type eye development;GO:0006351//transcription, DNA-templated" "gi|148705403|gb|EDL37350.1|/0/zinc finger protein 513, isoform CRA_b, partial [Mus musculus]" 668128 2133 0.506666667 1.36 1.424497829 Up 0.5185321 Gm8989 very large inducible GTPase 1 pseudogene - - - - gi|148684884|gb|EDL16831.1|/0/mCG127513 [Mus musculus] 619441 2231.18 1.113333333 2.163333333 0.958370376 Up 0.518466283 Tnfsfm13 "tumor necrosis factor (ligand) superfamily, membrane-bound member 13" K05475|1|9e-107|390|mmu:69583|tumor necrosis factor ligand superfamily member 13 GO:0009986//cell surface;GO:0044421;GO:0009986//cell surface;GO:0044421 GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0032813//tumor necrosis factor receptor superfamily binding GO:0002467//germinal center formation;GO:0045830//positive regulation of isotype switching;GO:0008283//cell proliferation;GO:0002467//germinal center formation;GO:0045830//positive regulation of isotype switching;GO:0008283//cell proliferation "gi|226958391|ref|NP_001152975.1|/0/tumor necrosis factor (ligand) superfamily, member 12-member 13 isoform c [Mus musculus]" 69837 908 3.496666667 5.083333333 0.539794565 Up 0.518344052 Pcgf1 polycomb group ring finger 1 K11487|1|3e-139|496|rno:103692167|polycomb group RING finger protein 1 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0010390//histone monoubiquitination gi|223590125|sp|Q8R023.2|PCGF1_MOUSE/2.68187e-138/RecName: Full=Polycomb group RING finger protein 1; AltName: Full=Nervous system Polycomb-1; Short=NSPc1; AltName: Full=RING finger protein 68 14871 1049 11.64666667 14.88666667 0.354103643 Up 0.518052578 Gstt1 "glutathione S-transferase, theta 1" K00799|1|6e-138|492|mmu:14871|glutathione S-transferase [EC:2.5.1.18] - - - - 56513 1248.49 3.95 5.626666667 0.510427845 Up 0.517817519 Pard6a par-6 family cell polarity regulator alpha K06093|1|3e-169|597|mmu:56513|partitioning defective protein 6 GO:0043296//apical junction complex;GO:0030426//growth cone;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0043296//apical junction complex;GO:0030426//growth cone;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0043296//apical junction complex;GO:0030426//growth cone;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0043296//apical junction complex;GO:0030426//growth cone;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0043296//apical junction complex;GO:0030426//growth cone;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0016020//membrane;GO:0032991//macromolecular complex GO:0017016//Ras GTPase binding;GO:0019901//protein kinase binding;GO:0017016//Ras GTPase binding;GO:0019901//protein kinase binding;GO:0017016//Ras GTPase binding;GO:0019901//protein kinase binding;GO:0017016//Ras GTPase binding;GO:0019901//protein kinase binding;GO:0017016//Ras GTPase binding;GO:0019901//protein kinase binding GO:0007163//establishment or maintenance of cell polarity;GO:0034331;GO:0032879//regulation of localization;GO:0007163//establishment or maintenance of cell polarity;GO:0034331;GO:0032879//regulation of localization;GO:0007163//establishment or maintenance of cell polarity;GO:0034331;GO:0032879//regulation of localization;GO:0007163//establishment or maintenance of cell polarity;GO:0034331;GO:0032879//regulation of localization;GO:0007163//establishment or maintenance of cell polarity;GO:0034331;GO:0032879//regulation of localization "gi|149038037|gb|EDL92397.1|/1.96379e-157/rCG51218, isoform CRA_b [Rattus norvegicus]" 109828 2709 4.006666667 2.606666667 -0.620196383 Down 0.517789311 C7 complement component 7 K03996|1|0.0|1766|mmu:109828|complement component 7 - - - - 21894 8560 39.39333333 32.21333333 -0.290293544 Down 0.517648276 Tln1 talin 1 K06271|1|0.0|4432|mmu:21894|talin GO:0005815//microtubule organizing center;GO:0031988//membrane-bounded vesicle;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0043227//membrane-bounded organelle;GO:0016020//membrane GO:0008092//cytoskeletal protein binding;GO:0005102//receptor binding;GO:0019904//protein domain specific binding;GO:0005198//structural molecule activity GO:0022610;GO:0030036//actin cytoskeleton organization;GO:0034329//cell junction assembly gi|49022858|dbj|BAC65702.4|/0/mKIAA1027 protein [Mus musculus] 14862 1310 309.7133333 371.2966667 0.26163887 Up 0.517544849 Gstm1 "glutathione S-transferase, mu 1" K00799|1|1e-126|455|mmu:14862|glutathione S-transferase [EC:2.5.1.18] GO:0044424 "GO:0042802//identical protein binding;GO:0008289//lipid binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0046983//protein dimerization activity;GO:0072341//modified amino acid binding" GO:0009636//response to toxic substance;GO:0007606//sensory perception of chemical stimulus;GO:0010038//response to metal ion;GO:0001101//response to acid chemical;GO:0006805//xenobiotic metabolic process;GO:0033554//cellular response to stress;GO:0006790//sulfur compound metabolic process;GO:0006807//nitrogen compound metabolic process;GO:0042493//response to drug "gi|148669991|gb|EDL01938.1|/4.80666e-130/mCG131602, isoform CRA_c, partial [Mus musculus]" 28106 913 16.87666667 21.14 0.324945393 Up 0.517281583 Mydgf myeloid derived growth factor - GO:0044432 - GO:0030968//endoplasmic reticulum unfolded protein response gi|26362060|dbj|BAB25931.2|/2.10001e-82/unnamed protein product [Mus musculus] 13197 1224 7.956666667 10.46 0.394646786 Up 0.517225168 Gadd45a growth arrest and DNA-damage-inducible 45 alpha K04402|1|3e-90|334|mmu:13197|growth arrest and DNA-damage-inducible protein GO:0043231//intracellular membrane-bounded organelle GO:0044212//transcription regulatory region DNA binding GO:0012501//programmed cell death;GO:0035556//intracellular signal transduction;GO:0006259//DNA metabolic process;GO:0022402//cell cycle process;GO:0010212//response to ionizing radiation;GO:0051726//regulation of cell cycle;GO:0033554//cellular response to stress;GO:0001933//negative regulation of protein phosphorylation;GO:0072593//reactive oxygen species metabolic process;GO:0009612//response to mechanical stimulus gi|6681149|ref|NP_031862.1|/2.85634e-89/growth arrest and DNA damage-inducible protein GADD45 alpha [Mus musculus] 14936 3681 93.36666667 77.24 -0.273559413 Down 0.517178156 Gys1 "glycogen synthase 1, muscle" K00693|1|0.0|1324|mmu:14936|glycogen(starch) synthase [EC:2.4.1.11] GO:0044424 GO:0048029//monosaccharide binding;GO:0035251//UDP-glucosyltransferase activity;GO:0019900//kinase binding GO:0044767//single-organism developmental process;GO:0005977//glycogen metabolic process "gi|31560022|ref|NP_109603.2|/0/glycogen [starch] synthase, muscle [Mus musculus]" 233877 1654 4.3 6.056666667 0.494187354 Up 0.516952499 Kctd13 potassium channel tetramerisation domain containing 13 K15074|1|2e-142|508|mmu:233877|BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein GO:0043231//intracellular membrane-bounded organelle;GO:0031461//cullin-RING ubiquitin ligase complex GO:0017048//Rho GTPase binding;GO:0019787//ubiquitin-like protein transferase activity "GO:0006351//transcription, DNA-templated;GO:0007266//Rho protein signal transduction;GO:0051017//actin filament bundle assembly;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0048870//cell motility;GO:0051259//protein oligomerization;GO:0032446//protein modification by small protein conjugation;GO:0006260//DNA replication" gi|27370096|ref|NP_766335.1|/1.67973e-141/BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 [Mus musculus] 17356 7401 9.94 7.556666667 -0.395495867 Down 0.516858475 Mllt4 "myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4" K05702|1|0.0|3290|mmu:17356|afadin GO:0005911//cell-cell junction;GO:0044444//cytoplasmic part;GO:0070161;GO:0016020//membrane;GO:0031981//nuclear lumen GO:0019904//protein domain specific binding GO:0022610;GO:0007154//cell communication gi|145587092|ref|NP_034936.1|/0/afadin [Mus musculus] 320204 1688 10.33333333 13.30333333 0.364482063 Up 0.516830268 Mettl20 methyltransferase like 20 - GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0008168//methyltransferase activity;GO:0008168//methyltransferase activity;GO:0008168//methyltransferase activity;GO:0008168//methyltransferase activity;GO:0008168//methyltransferase activity GO:0008213;GO:0008213;GO:0008213;GO:0008213;GO:0008213 "gi|148678812|gb|EDL10759.1|/6.06964e-157/RIKEN cDNA 4833442J19, isoform CRA_a, partial [Mus musculus]" 20365 610 5.223333333 3.62 -0.528981077 Down 0.516567001 Serf1 small EDRK-rich factor 1 - - - GO:0048731//system development "gi|564299702|ref|XP_001070716.3|/6.0917e-31/PREDICTED: uncharacterized protein Serf1, partial [Rattus norvegicus]" 13643 3231 29.95333333 24.26666667 -0.303740611 Down 0.516529392 Efnb3 ephrin B3 K05463|1|6e-152|541|mmu:13643|ephrin-B GO:0016021//integral component of membrane GO:0005102//receptor binding;GO:0005003//ephrin receptor activity GO:0007411//axon guidance;GO:0008344//adult locomotory behavior;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|6681281|ref|NP_031937.1|/5.26846e-151/ephrin-B3 precursor [Mus musculus] 84094 2033 4.763333333 6.616666667 0.474133091 Up 0.516454173 Plvap plasmalemma vesicle associated protein K17309|1|0.0|694|mmu:84094|plasmalemma vesicle-associated protein GO:0044459;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane GO:0042802//identical protein binding - gi|255522953|ref|NP_115774.2|/0/plasmalemma vesicle-associated protein [Mus musculus] 72416 4638 37.85666667 30.95 -0.290607976 Down 0.516209711 Lrpprc leucine-rich PPR-motif containing "K17964|1|0.0|2528|mmu:72416|leucine-rich PPR motif-containing protein, mitochondrial" GO:0032991//macromolecular complex;GO:0005759//mitochondrial matrix;GO:0031965//nuclear membrane;GO:0015630//microtubule cytoskeleton;GO:0000228//nuclear chromosome;GO:0019866//organelle inner membrane GO:0003779//actin binding;GO:0015631//tubulin binding;GO:0043566//structure-specific DNA binding "GO:0006351//transcription, DNA-templated;GO:0050658//RNA transport;GO:0000957//mitochondrial RNA catabolic process;GO:0006417//regulation of translation" "gi|134031976|ref|NP_082509.2|/0/leucine-rich PPR motif-containing protein, mitochondrial precursor [Mus musculus]" 67389 1339 6.046666667 8.126666667 0.42652367 Up 0.515720787 Fam132a "family with sequence similarity 132, member A" - - - - - 68090 1493 42.58666667 51.74666667 0.28106412 Up 0.515579751 Yif1a Yip1 interacting factor homolog A (S. cerevisiae) K20362|1|2e-161|571|mmu:68090|protein transport protein YIF1 GO:0005815//microtubule organizing center;GO:0012505//endomembrane system;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0045184//establishment of protein localization;GO:0006810//transport gi|25282409|ref|NP_080829.1|/1.84285e-160/protein YIF1A [Mus musculus] 18648 1855 84.00666667 69.89333333 -0.26534897 Down 0.515213058 Pgam1 phosphoglycerate mutase 1 "K01834|1|8e-138|493|rno:24642|2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]" GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0019900//kinase binding;GO:0016868//intramolecular transferase activity, phosphotransferases;GO:0034416//bisphosphoglycerate phosphatase activity" GO:0006098//pentose-phosphate shunt;GO:0006096//glycolytic process gi|403259801|ref|XP_003922386.1|/3.9365e-142/PREDICTED: phosphoglycerate mutase 1 [Saimiri boliviensis boliviensis] 100124467 83 20.73333333 16.61333333 -0.319610512 Down 0.515213058 Mir568 microRNA 568 - - - - - 71704 3703.35 13.02333333 10.12333333 -0.363414347 Down 0.515194253 Arhgef3 Rho guanine nucleotide exchange factor (GEF) 3 K20045|1|7e-27|125|mze:101467790|intersectin GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding GO:0007266//Rho protein signal transduction;GO:0012501//programmed cell death;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007266//Rho protein signal transduction;GO:0012501//programmed cell death;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway "gi|148692780|gb|EDL24727.1|/0/Rho guanine nucleotide exchange factor (GEF) 3, partial [Mus musculus]" 100043189 1363 8 5.926666667 -0.432779082 Down 0.515194253 Gm4285 predicted gene 4285 - - - - - 225995 1631 4.576666667 6.363333333 0.475485477 Up 0.515147241 D030056L22Rik RIKEN cDNA D030056L22 gene - - - - "gi|148709620|gb|EDL41566.1|/2.20116e-69/RIKEN cDNA D030056L22, isoform CRA_b, partial [Mus musculus]" 80748 2809 67.46333333 81.43666667 0.271574908 Up 0.515081425 BC004004 cDNA sequence BC004004 K20412|1|2e-157|558|ngi:103739648|peptidase inhibitor 16 GO:0044424;GO:0031224//intrinsic component of membrane - GO:0009611//response to wounding;GO:0051726//regulation of cell cycle;GO:0008283//cell proliferation gi|569002159|ref|XP_006525236.1|/0/PREDICTED: bombesin receptor-activated protein C6orf89 homolog isoform X2 [Mus musculus] 73075 1093 0.636666667 1.51 1.245938412 Up 0.514583098 Ppil6 peptidylprolyl isomerase (cyclophilin)-like 6 K12739|1|3e-176|620|mmu:73075|peptidyl-prolyl cis-trans isomerase-like 6 [EC:5.2.1.8] - GO:0016859//cis-trans isomerase activity GO:0044267//cellular protein metabolic process gi|162329596|ref|NP_082706.1|/2.19583e-175/peptidyl-prolyl cis-trans isomerase-like 6 [Mus musculus] 100306955 139 2.823333333 1.65 -0.774933444 Down 0.514573696 Snora43 "small nucleolar RNA, H/ACA box 43" - - - - - 66857 1974 29.75666667 36.37333333 0.289668218 Up 0.514536086 Plbd1 phospholipase B domain containing 1 - - GO:0003824//catalytic activity GO:0006629//lipid metabolic process gi|13385274|ref|NP_080082.1|/0/phospholipase B-like 1 precursor [Mus musculus] 21687 4597.52 13.06333333 10.2 -0.35695392 Down 0.514084772 Tek endothelial-specific receptor tyrosine kinase K05121|1|0.0|2101|mmu:21687|endothelial-specific receptor tyrosine kinase [EC:2.7.10.1] GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0032432//actin filament bundle;GO:0042995//cell projection;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0032432//actin filament bundle;GO:0042995//cell projection;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0030054//cell junction;GO:0032432//actin filament bundle;GO:0042995//cell projection;GO:0016021//integral component of membrane GO:0004713//protein tyrosine kinase activity;GO:0032550;GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0032550;GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0032550;GO:0005515//protein binding GO:0006461//protein complex assembly;GO:0003206//cardiac chamber morphogenesis;GO:0001935//endothelial cell proliferation;GO:0048534//hematopoietic or lymphoid organ development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0031532//actin cytoskeleton reorganization;GO:0043410//positive regulation of MAPK cascade;GO:0007163//establishment or maintenance of cell polarity;GO:0000904//cell morphogenesis involved in differentiation;GO:0036075;GO:0001934//positive regulation of protein phosphorylation;GO:0010594//regulation of endothelial cell migration;GO:0046683//response to organophosphorus;GO:0048545//response to steroid hormone;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0001525//angiogenesis;GO:0006950//response to stress;GO:0043066//negative regulation of apoptotic process;GO:0001954//positive regulation of cell-matrix adhesion;GO:0006461//protein complex assembly;GO:0003206//cardiac chamber morphogenesis;GO:0001935//endothelial cell proliferation;GO:0048534//hematopoietic or lymphoid organ development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0031532//actin cytoskeleton reorganization;GO:0043410//positive regulation of MAPK cascade;GO:0007163//establishment or maintenance of cell polarity;GO:0000904//cell morphogenesis involved in differentiation;GO:0036075;GO:0001934//positive regulation of protein phosphorylation;GO:0010594//regulation of endothelial cell migration;GO:0046683//response to organophosphorus;GO:0048545//response to steroid hormone;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0001525//angiogenesis;GO:0006950//response to stress;GO:0043066//negative regulation of apoptotic process;GO:0001954//positive regulation of cell-matrix adhesion;GO:0006461//protein complex assembly;GO:0003206//cardiac chamber morphogenesis;GO:0001935//endothelial cell proliferation;GO:0048534//hematopoietic or lymphoid organ development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0031532//actin cytoskeleton reorganization;GO:0043410//positive regulation of MAPK cascade;GO:0007163//establishment or maintenance of cell polarity;GO:0000904//cell morphogenesis involved in differentiation;GO:0036075;GO:0001934//positive regulation of protein phosphorylation;GO:0010594//regulation of endothelial cell migration;GO:0046683//response to organophosphorus;GO:0048545//response to steroid hormone;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0001525//angiogenesis;GO:0006950//response to stress;GO:0043066//negative regulation of apoptotic process;GO:0001954//positive regulation of cell-matrix adhesion gi|111185951|ref|NP_038718.2|/0/angiopoietin-1 receptor isoform 1 precursor [Mus musculus] 56529 1113 16.36666667 20.39333333 0.317337082 Up 0.513981346 Sec11a "SEC11 homolog A, signal peptidase complex subunit" "K13280|1|4e-95|350|tup:102473151|signal peptidase, endoplasmic reticulum-type [EC:3.4.-.-]" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0030073//insulin secretion;GO:0015980//energy derivation by oxidation of organic compounds;GO:0006613//cotranslational protein targeting to membrane;GO:0016485//protein processing "gi|34784421|gb|AAH57885.1|/6.04654e-112/Sec11a protein, partial [Mus musculus]" 15360 3294 9.026666667 6.786666667 -0.411490177 Down 0.513877919 Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 K01641|1|0.0|1026|mmu:15360|hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] - - - - 17329 2905 1.843333333 3.05 0.726492263 Up 0.5138027 Cxcl9 chemokine (C-X-C motif) ligand 9 K05416|1|3e-42|174|mmu:17329|C-X-C motif chemokine 9 GO:0009986//cell surface;GO:0044421 GO:0005125//cytokine activity;GO:0045236//CXCR chemokine receptor binding GO:0050927//positive regulation of positive chemotaxis;GO:0006952//defense response;GO:0002252 gi|74152478|dbj|BAE33966.1|/1.75906e-60/unnamed protein product [Mus musculus] 232196 2645.73 3.996666667 5.666666667 0.503703088 Up 0.513473617 C87436 expressed sequence C87436 K13201|1|1e-31|140|tgu:100224743|nucleolysin TIA-1/TIAR;K02599|2|3e-29|133|bfo:BRAFLDRAFT_101343|Notch - - - gi|225543411|ref|NP_666282.3|/0/uncharacterized protein C2orf42 homolog isoform 1 [Mus musculus] 243277 5163 3.506666667 2.22 -0.659540622 Down 0.513454812 Adgrd1 adhesion G protein-coupled receptor D1 K08465|1|0.0|1785|mmu:243277|G protein-coupled receptor 133 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007186//G-protein coupled receptor signaling pathway gi|124486787|ref|NP_001074811.1|/0/adhesion G-protein coupled receptor D1 precursor [Mus musculus] 68073 1166 6.773333333 9.003333333 0.410593238 Up 0.513294972 Fam173b "family with sequence similarity 173, member B" - GO:0031224//intrinsic component of membrane - - gi|21312640|ref|NP_080822.1|/1.58548e-134/protein FAM173B [Mus musculus] 17434 1870.86 6.706666667 8.933333333 0.413602696 Up 0.513294972 Mocs2 molybdenum cofactor synthesis 2 K03635|1|1e-102|376|mmu:17434|molybdopterin synthase catalytic subunit [EC:2.8.1.12] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0003824//catalytic activity GO:0009108//coenzyme biosynthetic process;GO:0009108//coenzyme biosynthetic process;GO:0009108//coenzyme biosynthetic process gi|164664484|ref|NP_001106846.1|/3.38145e-81/molybdopterin synthase sulfur carrier subunit isoform Mocs2B2 [Mus musculus] 237781 2564 20.08 16.09666667 -0.318997306 Down 0.513257362 Mief2 mitochondrial elongation factor 2 - GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane - GO:0006996//organelle organization gi|57862819|ref|NP_001009927.1|/0/mitochondrial dynamics protein MID49 [Mus musculus] 71520 1599 9.186666667 11.86 0.368490623 Up 0.513069314 Grap GRB2-related adaptor protein K04364|1|5e-114|414|mcc:702473|growth factor receptor-binding protein 2 GO:0044444//cytoplasmic part "GO:0030674//protein binding, bridging" GO:0007264//small GTPase mediated signal transduction gi|21362273|ref|NP_082093.1|/3.36156e-123/GRB2-related adapter protein [Mus musculus] 77032 1612 14.05666667 17.65666667 0.328958487 Up 0.512721426 Tstd3 thiosulfate sulfurtransferase (rhodanese)-like domain containing 3 K01011|1|1e-18|97.4|dme:Dmel_CG12279|thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2];K06089|2|2e-12|76.6|asn:102383480|junctional adhesion molecule 1 - GO:0016783//sulfurtransferase activity - gi|244790037|ref|NP_084116.1|/1.49393e-78/thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 [Mus musculus] 108012 2332.66 8.843333333 6.633333333 -0.414856245 Down 0.512505171 Ap1s2 "adaptor-related protein complex 1, sigma 2 subunit" K12394|1|2e-102|375|ggo:101143987|AP-1 complex subunit sigma 1/2 - - - - 67862 1243 5.806666667 7.83 0.431302089 Up 0.512448757 2310033P09Rik RIKEN cDNA 2310033P09 gene - - - - gi|564372270|ref|XP_006246548.1|/1.28722e-90/PREDICTED: multiple myeloma tumor-associated protein 2 homolog isoform X1 [Rattus norvegicus] 56150 1725 1.143333333 2.173333333 0.926663388 Up 0.512138478 Mad2l1 MAD2 mitotic arrest deficient-like 1 K02537|1|9e-112|406|mmu:56150|mitotic spindle assembly checkpoint protein MAD2 "GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0000775//chromosome, centromeric region;GO:0044444//cytoplasmic part" GO:0042802//identical protein binding GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0006915//apoptotic process;GO:0009895;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0090232//positive regulation of spindle checkpoint "gi|148666370|gb|EDK98786.1|/1.66896e-115/mCG125314, isoform CRA_b, partial [Mus musculus]" 74257 1567 7.773333333 5.766666667 -0.430795751 Down 0.511875212 Tspan17 tetraspanin 17 K10303|1|2e-151|538|mmu:74257|F-box protein 23 GO:0031224//intrinsic component of membrane - - "gi|148668905|gb|EDL01067.1|/1.84206e-150/tetraspanin 17, isoform CRA_a [Mus musculus]" 216964 1366 5.796666667 7.803333333 0.428867002 Up 0.511875212 Trp53i13 transformation related protein 53 inducible protein 13 - GO:0016020//membrane - - gi|67906197|ref|NP_001020091.1|/3.43463e-126/tumor protein p53-inducible protein 13 precursor [Mus musculus] 56218 3127.39 5.82 7.826666667 0.427378849 Up 0.511875212 Patz1 POZ (BTB) and AT hook containing zinc finger 1 K17559|1|1e-58|231|chx:102182741|phostensin;K09228|2|4e-37|159|obi:106880329|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0043169//cation binding;GO:0043169//cation binding;GO:0043169//cation binding "GO:0030098//lymphocyte differentiation;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0008406//gonad development;GO:0030098//lymphocyte differentiation;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0008406//gonad development;GO:0030098//lymphocyte differentiation;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0008406//gonad development;GO:0030098//lymphocyte differentiation;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0008406//gonad development;GO:0030098//lymphocyte differentiation;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0008406//gonad development" "gi|148708460|gb|EDL40407.1|/2.90244e-148/zinc finger protein 278, isoform CRA_g, partial [Mus musculus]" 102657 3197 2.063333333 3.31 0.681854308 Up 0.511837602 Cd276 CD276 antigen K06746|1|2e-157|559|mmu:102657|immune costimulatory protein B7-H3 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0005515//protein binding GO:0001649//osteoblast differentiation;GO:0042095//interferon-gamma biosynthetic process;GO:0030282//bone mineralization;GO:0006954//inflammatory response;GO:0002682//regulation of immune system process;GO:0042036//negative regulation of cytokine biosynthetic process;GO:0042098//T cell proliferation gi|19527206|ref|NP_598744.1|/1.84721e-156/CD276 antigen precursor [Mus musculus] 243362 5581 8.196666667 6.12 -0.421505676 Down 0.511781188 Stard13 StAR-related lipid transfer (START) domain containing 13 K07526|1|2e-13|82.0|cbr:CBG06126|SLIT-ROBO Rho GTPase activating protein;K08773|3|9e-13|79.7|crg:105342928|RalA-binding protein 1;K05732|4|2e-12|79.0|tru:101068709|glucocorticoid receptor DNA-binding factor 1;K10360|5|4e-12|77.8|soc:105194477|myosin IX - - - "gi|148673941|gb|EDL05888.1|/0/serologically defined colon cancer antigen 13, isoform CRA_b, partial [Mus musculus]" 18073 6046 33.81666667 27.63333333 -0.291324858 Down 0.511771785 Nid1 nidogen 1 K06826|1|0.0|2522|mmu:18073|nidogen (entactin) GO:0044464;GO:0005604//basement membrane GO:0043236//laminin binding GO:0010810//regulation of cell-substrate adhesion;GO:0030198//extracellular matrix organization gi|171543883|ref|NP_035047.2|/0/nidogen-1 precursor [Mus musculus] 14790 568 126.6 151.6966667 0.26091198 Up 0.511658957 Grcc10 "gene rich cluster, C10 gene" - - - - gi|537136500|gb|ERE66552.1|/1.15456e-51/atrophin-1-like protein [Cricetulus griseus] 68816 1215 22.52666667 27.64333333 0.295297742 Up 0.511583738 Ppil1 peptidylprolyl isomerase (cyclophilin)-like 1 K12733|1|1e-86|322|mmu:68816|peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8] GO:0005681//spliceosomal complex GO:0016859//cis-trans isomerase activity;GO:0005488//binding GO:0000377;GO:0018208//peptidyl-proline modification gi|21312784|ref|NP_081121.1|/1.11041e-85/peptidyl-prolyl cis-trans isomerase-like 1 [Mus musculus] 30957 5532.22 27.09666667 21.98333333 -0.301705229 Down 0.511461507 Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 K04436|1|0.0|2400|mmu:30957|mitogen-activated protein kinase 8 interacting protein 3 GO:0031982//vesicle;GO:0032589//neuron projection membrane;GO:0005783//endoplasmic reticulum;GO:0031982//vesicle;GO:0032589//neuron projection membrane;GO:0005783//endoplasmic reticulum;GO:0031982//vesicle;GO:0032589//neuron projection membrane;GO:0012505//endomembrane system;GO:0005783//endoplasmic reticulum;GO:0031982//vesicle;GO:0032589//neuron projection membrane;GO:0005783//endoplasmic reticulum;GO:0031982//vesicle;GO:0032589//neuron projection membrane;GO:0005783//endoplasmic reticulum;GO:0031982//vesicle;GO:0032589//neuron projection membrane;GO:0005783//endoplasmic reticulum;GO:0031982//vesicle;GO:0032589//neuron projection membrane;GO:0005783//endoplasmic reticulum "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0032947//protein complex scaffold;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0032947//protein complex scaffold;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0032947//protein complex scaffold;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0032947//protein complex scaffold;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0032947//protein complex scaffold;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0032947//protein complex scaffold;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0032947//protein complex scaffold" GO:0033036;GO:0006810//transport;GO:0030324//lung development;GO:0010467//gene expression;GO:0043009//chordate embryonic development;GO:0007254//JNK cascade;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0009887//organ morphogenesis;GO:0000187//activation of MAPK activity;GO:0030182//neuron differentiation;GO:0033036;GO:0006810//transport;GO:0030324//lung development;GO:0010467//gene expression;GO:0043009//chordate embryonic development;GO:0007254//JNK cascade;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0009887//organ morphogenesis;GO:0000187//activation of MAPK activity;GO:0030182//neuron differentiation;GO:0033036;GO:0006810//transport;GO:0030324//lung development;GO:0010467//gene expression;GO:0043009//chordate embryonic development;GO:0007254//JNK cascade;GO:0007420//brain development;GO:0030030//cell projection organization;GO:0006935//chemotaxis;GO:0009887//organ morphogenesis;GO:0000187//activation of MAPK activity;GO:0030182//neuron differentiation;GO:0033036;GO:0006810//transport;GO:0030324//lung development;GO:0010467//gene expression;GO:0043009//chordate embryonic development;GO:0007254//JNK cascade;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0009887//organ morphogenesis;GO:0000187//activation of MAPK activity;GO:0030182//neuron differentiation;GO:0033036;GO:0006810//transport;GO:0030324//lung development;GO:0010467//gene expression;GO:0043009//chordate embryonic development;GO:0007254//JNK cascade;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0009887//organ morphogenesis;GO:0000187//activation of MAPK activity;GO:0030182//neuron differentiation;GO:0033036;GO:0006810//transport;GO:0030324//lung development;GO:0010467//gene expression;GO:0043009//chordate embryonic development;GO:0007254//JNK cascade;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0009887//organ morphogenesis;GO:0000187//activation of MAPK activity;GO:0030182//neuron differentiation;GO:0033036;GO:0006810//transport;GO:0030324//lung development;GO:0010467//gene expression;GO:0043009//chordate embryonic development;GO:0007254//JNK cascade;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0009887//organ morphogenesis;GO:0000187//activation of MAPK activity;GO:0030182//neuron differentiation "gi|148690438|gb|EDL22385.1|/0/mitogen-activated protein kinase 8 interacting protein 3, isoform CRA_b, partial [Mus musculus]" 11722 1797 4.213333333 2.816666667 -0.580973217 Down 0.511235849 Amy1 "amylase 1, salivary" K01176|1|0.0|1095|mmu:11722|alpha-amylase [EC:3.2.1.1] GO:0044421;GO:0044421 GO:0046872//metal ion binding;GO:0043168//anion binding;GO:0016160//amylase activity;GO:0046872//metal ion binding;GO:0043168//anion binding;GO:0016160//amylase activity GO:0005975//carbohydrate metabolic process;GO:0005975//carbohydrate metabolic process gi|160358819|ref|NP_031472.2|/0/alpha-amylase 1 precursor [Mus musculus] 216850 6654 15.27 12.06666667 -0.339672866 Down 0.511104216 Kdm6b KDM1 lysine (K)-specific demethylase 6B K11448|1|0.0|2164|mmu:216850|lysine-specific demethylase 6B [EC:1.14.11.-] - GO:0003677//DNA binding GO:0006482//protein demethylation;GO:0006366//transcription from RNA polymerase II promoter gi|62945394|ref|NP_001017426.1|/0/lysine-specific demethylase 6B [Mus musculus] 387217 74 0.483333333 0.01 -5.594946589 Down 0.510972583 Mir23b microRNA 23b - - - - - 12350 1537 0.48 0.01 -5.584962501 Down 0.510972583 Car3 carbonic anhydrase 3 K01672|1|2e-158|561|mmu:12350|carbonic anhydrase [EC:4.2.1.1] GO:0044424 GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0044237//cellular metabolic process;GO:0006950//response to stress gi|31982861|ref|NP_031632.2|/1.97774e-157/carbonic anhydrase 3 [Mus musculus] 102465885 137 0.483333333 0.01 -5.594946589 Down 0.510972583 Mir8093 microRNA 8093 - - - - - 100041034 1462 0.01 0.476666667 5.574908836 Up 0.510784535 LOC100041034 Sp110 nuclear body protein pseudogene K15413|1|6e-25|117|umr:103662689|nuclear autoantigen Sp-100 - - - - 100040880 858 0.476666667 0.01 -5.574908836 Down 0.510784535 Gm3020 predicted gene 3020 "K03844|1|9e-19|96.3|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - gi|755546841|ref|XP_011243026.1|/1.62754e-116/PREDICTED: predicted gene 3264 isoform X1 [Mus musculus] 71538 2115.67 11.95 15.12666667 0.34008349 Up 0.510746925 Fbxo9 f-box protein 9 K10295|1|0.0|893|mmu:71538|F-box protein 9 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex - GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0009966//regulation of signal transduction;GO:0032446//protein modification by small protein conjugation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0009966//regulation of signal transduction;GO:0032446//protein modification by small protein conjugation gi|125628675|ref|NP_001074959.1|/0/F-box only protein 9 isoform 2 [Mus musculus] 68151 2701.52 15.20333333 19.03333333 0.324140575 Up 0.510699913 Wls wntless homolog (Drosophila) - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012506//vesicle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012506//vesicle membrane GO:0005515//protein binding;GO:0005515//protein binding GO:0030177//positive regulation of Wnt signaling pathway;GO:0009798//axis specification;GO:0001704//formation of primary germ layer;GO:0030177//positive regulation of Wnt signaling pathway;GO:0009798//axis specification;GO:0001704//formation of primary germ layer "gi|148679892|gb|EDL11839.1|/0/G protein-coupled receptor 177, isoform CRA_a, partial [Mus musculus]" 620913 5287 0.266666667 1 1.906890596 Up 0.510681109 Gm12185 predicted gene 12185 K17072|1|0.0|1022|mmu:432555|interferon gamma inducible protein 47 - GO:0016787//hydrolase activity GO:0006950//response to stress gi|113865923|ref|NP_001039005.1|/0/interferon inducible GTPase [Mus musculus] 68058 2989 4.14 5.806666667 0.48807945 Up 0.510643499 Chd1l chromodomain helicase DNA binding protein 1-like K20092|1|0.0|1576|mmu:68058|chromodomain-helicase-DNA-binding protein 1-like [EC:3.6.4.12] GO:0031981//nuclear lumen;GO:0016020//membrane GO:0032550;GO:0003676//nucleic acid binding;GO:0003678//DNA helicase activity GO:0006259//DNA metabolic process;GO:0009154//purine ribonucleotide catabolic process;GO:0033554//cellular response to stress;GO:0016568//chromatin modification gi|13386044|ref|NP_080815.1|/0/chromodomain-helicase-DNA-binding protein 1-like [Mus musculus] 16477 1840 18.63666667 23.02666667 0.305161738 Up 0.510577683 Junb jun B proto-oncogene K09028|1|0.0|636|cge:103161432|transcription factor jun-B GO:0031981//nuclear lumen GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0043566//structure-specific DNA binding "GO:0006351//transcription, DNA-templated;GO:0009605//response to external stimulus;GO:0048568//embryonic organ development;GO:0002573//myeloid leukocyte differentiation;GO:0051592//response to calcium ion;GO:0008283//cell proliferation;GO:0046683//response to organophosphorus;GO:0001503//ossification;GO:0051384//response to glucocorticoid;GO:0001893//maternal placenta development;GO:0009314//response to radiation;GO:0001825//blastocyst formation;GO:0007049//cell cycle" gi|625262091|ref|XP_007622475.1|/6.14618e-180/PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC103161432 [Cricetulus griseus] 71887 1733 13.81 10.87 -0.345361379 Down 0.51013577 Ppm1j protein phosphatase 1J K17504|1|0.0|914|mmu:71887|protein phosphatase 1J [EC:3.1.3.16] - GO:0004721//phosphoprotein phosphatase activity;GO:0005488//binding GO:0006464//cellular protein modification process gi|114205424|ref|NP_082258.2|/0/protein phosphatase 1J [Mus musculus] 208922 5836.27 11.34333333 8.76 -0.372841876 Down 0.510041747 Cpeb3 cytoplasmic polyadenylation element binding protein 3 K02602|1|0.0|1180|mmu:208922|cytoplasmic polyadenylation element-binding protein - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0006412//translation;GO:0006412//translation;GO:0006412//translation;GO:0006412//translation gi|26006231|dbj|BAC41458.1|/0/mKIAA0940 protein [Mus musculus] 24056 2487 26.62666667 32.55 0.289785711 Up 0.510013539 Sh3bp5 SH3-domain binding protein 5 (BTK-associated) K20478|1|1e-26|124|hro:HELRODRAFT_191501|golgin subfamily B member 1;K10352|2|2e-07|60.5|acs:100552510|myosin heavy chain GO:0043231//intracellular membrane-bounded organelle GO:0019904//protein domain specific binding;GO:0019887//protein kinase regulator activity GO:0051403//stress-activated MAPK cascade;GO:0001933//negative regulation of protein phosphorylation "gi|148692860|gb|EDL24807.1|/0/SH3-domain binding protein 5 (BTK-associated), isoform CRA_a, partial [Mus musculus]" 24051 3727 36.01333333 43.61 0.276127851 Up 0.50993832 Sgcb "sarcoglycan, beta (dystrophin-associated glycoprotein)" K12566|1|2e-169|599|mmu:24051|beta-sarcoglycan GO:0043232;GO:0016011//dystroglycan complex;GO:0016021//integral component of membrane - GO:0007507//heart development;GO:0006996//organelle organization gi|6755482|ref|NP_036020.1|/1.46724e-168/beta-sarcoglycan [Mus musculus] 76927 481 5.813333333 4.153333333 -0.485095972 Down 0.509834894 Tsacc TSSK6 activating co-chaperone K06580|1|7e-21|70.1|fca:101084679|ammonium transporter Rh GO:0044424 GO:0031072//heat shock protein binding;GO:0019900//kinase binding GO:0001934//positive regulation of protein phosphorylation gi|113199759|ref|NP_084077.1|/9.9326e-67/TSSK6-activating co-chaperone protein [Mus musculus] 56222 1258 11.75666667 14.89333333 0.34118761 Up 0.509703261 Cited4 "Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4" - GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity "GO:0048545//response to steroid hormone;GO:0006351//transcription, DNA-templated" gi|9625010|ref|NP_062509.1|/4.93745e-60/cbp/p300-interacting transactivator 4 [Mus musculus] 17151 1572 15.36666667 19.12666667 0.315781217 Up 0.509487006 Ccndbp1 cyclin D-type binding-protein 1 - GO:0043231//intracellular membrane-bounded organelle - GO:0007049//cell cycle "gi|148696081|gb|EDL28028.1|/0/cyclin D-type binding-protein 1, isoform CRA_b, partial [Mus musculus]" 66818 2842 21.26 26.16333333 0.299404762 Up 0.509477604 Smim7 small integral membrane protein 7 K15169|1|3e-09|67.0|cge:100755356|mediator of RNA polymerase II transcription subunit 26 GO:0031224//intrinsic component of membrane - - gi|528768788|gb|EPY88447.1|/1.56479e-34/hypothetical protein CB1_000172020 [Camelus ferus] 68119 1616 9.693333333 12.40666667 0.356050786 Up 0.509327165 Cmtm3 CKLF-like MARVEL transmembrane domain containing 3 - GO:0031224//intrinsic component of membrane;GO:0044421 GO:0005102//receptor binding GO:0042221//response to chemical gi|13195644|ref|NP_077179.1|/6.29425e-85/CKLF-like MARVEL transmembrane domain-containing protein 3 [Mus musculus] 382867 4318 18.01 22.29666667 0.308029863 Up 0.509054496 Zfp488 zinc finger protein 488 K16660|1|3e-18|97.4|dgr:Dgri_GH14523|reticulon-4 receptor-like 1;K11290|2|4e-11|73.9|rno:317165|template-activating factor I;K09230|4|5e-06|57.0|tup:102473365|SCAN domain-containing zinc finger protein - - - - 20598 1621 21.09 25.95 0.299175443 Up 0.509035691 Smpd2 "sphingomyelin phosphodiesterase 2, neutral" K12351|1|0.0|792|mmu:20598|sphingomyelin phosphodiesterase 2 [EC:3.1.4.12] GO:0016021//integral component of membrane;GO:0044459 GO:0043169//cation binding;GO:0004620//phospholipase activity GO:0006644//phospholipid metabolic process;GO:0035556//intracellular signal transduction;GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006664//glycolipid metabolic process;GO:0006672//ceramide metabolic process;GO:0009605//response to external stimulus gi|6678031|ref|NP_033239.1|/0/sphingomyelin phosphodiesterase 2 [Mus musculus] 68992 1119 4.553333333 6.29 0.466136939 Up 0.508828839 Zfp580 zinc finger protein 580 K09228|1|6e-17|90.9|cmy:102945139|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|674075192|ref|XP_008844919.1|/1.68004e-85/PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 580-like [Nannospalax galili] 52076 2861 10.55333333 13.43666667 0.348476528 Up 0.508772425 Tmem38b transmembrane protein 38B K10603|1|2e-11|74.3|fab:101813297|autoimmune regulator GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0005261//cation channel activity GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|21312532|ref|NP_082329.1|/9.89275e-146/trimeric intracellular cation channel type B [Mus musculus] 11908 2329 20.64 25.47333333 0.303544786 Up 0.508734815 Atf1 activating transcription factor 1 K09053|1|9e-121|437|mmu:11908|activating transcription factor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003677//DNA binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0006461//protein complex assembly;GO:0010033//response to organic substance;GO:0010975//regulation of neuron projection development;GO:0010038//response to metal ion;GO:0006260//DNA replication "gi|76779402|gb|AAI05854.1|/4.39709e-149/Atf1 protein, partial [Rattus norvegicus]" 218236 4919 40.99333333 33.72666667 -0.281499568 Down 0.508527963 Fam120a "family with sequence similarity 120, member A" - GO:0044424;GO:0016020//membrane GO:0003676//nucleic acid binding - gi|50510403|dbj|BAD32187.1|/0/mKIAA0183 protein [Mus musculus] 70231 2289.38 47.77666667 57.77 0.274014293 Up 0.508086051 Gorasp2 golgi reassembly stacking protein 2 - GO:0000139//Golgi membrane;GO:0031985//Golgi cisterna;GO:0016020//membrane;GO:0031985//Golgi cisterna GO:0005488//binding GO:0006996//organelle organization;GO:0006996//organelle organization "gi|148695121|gb|EDL27068.1|/0/golgi reassembly stacking protein 2, isoform CRA_d [Mus musculus]" 102465773 62 1.09 2.093333333 0.941473923 Up 0.508076648 Mir7672 microRNA 7672 - - - - - 14794 1220 2.03 3.25 0.678959991 Up 0.508020234 Spsb2 splA/ryanodine receptor domain and SOCS box containing 2 K10344|1|5e-155|543|cge:100757837|SPRY domain-containing SOCS box protein 2 GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation;GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation;GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation;GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation;GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation gi|568940718|ref|XP_006505628.1|/6.48207e-168/PREDICTED: SPRY domain-containing SOCS box protein 2 isoform X2 [Mus musculus] 100041306 519 0.993333333 1.97 0.9878458 Up 0.507841589 Gm3264 predicted gene 3264 "K03844|1|3e-17|89.7|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - - 53318 1578 10.44 13.28666667 0.347857498 Up 0.507775772 Pdlim3 PDZ and LIM domain 3 K19867|1|8e-40|167|crg:105335510|LIM domain-binding protein 3 GO:0005856//cytoskeleton;GO:0031674//I band GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity GO:0014706//striated muscle tissue development;GO:0044767//single-organism developmental process;GO:0030036//actin cytoskeleton organization gi|7948997|ref|NP_058078.1|/0/PDZ and LIM domain protein 3 [Mus musculus] 100042150 2839 0.093333333 0.693333333 2.893084796 Up 0.507597127 Nrg2 neuregulin 2 K05456|1|0.0|1192|mmu:100042150|neuregulin 2 GO:0031224//intrinsic component of membrane GO:0070851//growth factor receptor binding GO:0007275//multicellular organism development;GO:0038127//ERBB signaling pathway "gi|268607669|ref|NP_001161363.1|/0/pro-neuregulin-2, membrane-bound isoform [Mus musculus]" 17387 3801 5.653333333 7.593333333 0.425631577 Up 0.5074937 Mmp14 matrix metallopeptidase 14 (membrane-inserted) K07763|1|0.0|1051|mmu:17387|matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80] GO:0048770;GO:0031224//intrinsic component of membrane GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0008047//enzyme activator activity;GO:0001071//nucleic acid binding transcription factor activity GO:0009605//response to external stimulus;GO:0050673//epithelial cell proliferation;GO:0008585//female gonad development;GO:0048545//response to steroid hormone;GO:0001953//negative regulation of cell-matrix adhesion;GO:0008347//glial cell migration;GO:0016485//protein processing;GO:0051345//positive regulation of hydrolase activity;GO:0030323//respiratory tube development;GO:0060562//epithelial tube morphogenesis;GO:0006950//response to stress;GO:0016049//cell growth;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0032963//collagen metabolic process gi|188528637|ref|NP_032634.3|/0/matrix metalloproteinase-14 preproprotein [Mus musculus] 68920 785 7.546666667 5.603333333 -0.429554234 Down 0.5074937 1110065P20Rik RIKEN cDNA 1110065P20 gene - - - - "gi|119627719|gb|EAX07314.1|/3.44668e-61/chromosome 1 open reading frame 122, isoform CRA_b, partial [Homo sapiens]" 56447 1672 33.26 40.28666667 0.276514273 Up 0.507409079 Copz1 "coatomer protein complex, subunit zeta 1" K20472|1|5e-93|344|pale:102886457|coatomer subunit zeta GO:0030137//COPI-coated vesicle;GO:0030120//vesicle coat - GO:0035964//COPI-coated vesicle budding;GO:0015031//protein transport gi|926691076|ref|XP_013819122.1|/6.58482e-93/PREDICTED: coatomer subunit zeta-1 isoform X1 [Capra hircus] 52377 1453 17.49 21.65333333 0.308058843 Up 0.507315055 Rcn3 "reticulocalbin 3, EF-hand calcium binding domain" K19934|1|2e-33|145|sko:100368121|calcium-binding protein GO:0044432 GO:0046872//metal ion binding - "gi|148690850|gb|EDL22797.1|/0/reticulocalbin 3, EF-hand calcium binding domain, isoform CRA_a, partial [Mus musculus]" 433375 2138 83.72666667 100.1466667 0.258355308 Up 0.507042386 Creg1 cellular repressor of E1A-stimulated genes 1 K15704|1|2e-07|60.8|asn:106723329|E3 ubiquitin-protein ligase RNF149 [EC:2.3.2.27] GO:0043234//protein complex GO:0032553//ribonucleotide binding;GO:0003712//transcription cofactor activity;GO:0005515//protein binding;GO:0003824//catalytic activity GO:0044710;GO:0040007//growth;GO:0044699;GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter gi|6753520|ref|NP_035934.1|/8.63103e-104/protein CREG1 precursor [Mus musculus] 21835 1124 46.28 55.77333333 0.269186633 Up 0.506995374 Thrsp thyroid hormone responsive - - - - - 21847 3056 10.23333333 7.873333333 -0.378229691 Down 0.506967167 Klf10 Kruppel-like factor 10 K09209|1|0.0|864|mmu:21847|krueppel-like factor 10/11 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0071417//cellular response to organonitrogen compound;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0008283//cell proliferation;GO:0001503//ossification;GO:0019827//stem cell population maintenance;GO:0012502//induction of programmed cell death;GO:0006351//transcription, DNA-templated;GO:0071417//cellular response to organonitrogen compound;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0008283//cell proliferation;GO:0001503//ossification;GO:0019827//stem cell population maintenance;GO:0012502//induction of programmed cell death" gi|7305571|ref|NP_038720.1|/0/Krueppel-like factor 10 isoform 1 [Mus musculus] 14609 3105 55.89666667 46.41666667 -0.26811933 Down 0.506967167 Gja1 "gap junction protein, alpha 1" "K07372|1|0.0|706|fca:101100211|gap junction protein, alpha 1" GO:0000323//lytic vacuole;GO:0005921//gap junction;GO:0043234//protein complex;GO:0043232;GO:0031966//mitochondrial membrane;GO:0000139//Golgi membrane;GO:0044459;GO:0016021//integral component of membrane;GO:0005913//cell-cell adherens junction;GO:0005770//late endosome;GO:0044291//cell-cell contact zone GO:0060089;GO:0019904//protein domain specific binding;GO:0022829//wide pore channel activity;GO:0015631//tubulin binding GO:0006461//protein complex assembly;GO:0010467//gene expression;GO:0006954//inflammatory response;GO:0015711//organic anion transport;GO:0002064//epithelial cell development;GO:0001662//behavioral fear response;GO:0030278//regulation of ossification;GO:0019229//regulation of vasoconstriction;GO:0030010//establishment of cell polarity;GO:0009612//response to mechanical stimulus;GO:0043009//chordate embryonic development;GO:0031175//neuron projection development;GO:0014706//striated muscle tissue development;GO:0008016//regulation of heart contraction;GO:0042311//vasodilation;GO:0070830//bicellular tight junction assembly;GO:0003093//regulation of glomerular filtration;GO:0001837//epithelial to mesenchymal transition;GO:0016477//cell migration;GO:0010643//cell communication by chemical coupling;GO:0009896;GO:0001974//blood vessel remodeling;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0042246//tissue regeneration;GO:0043010//camera-type eye development;GO:0003254//regulation of membrane depolarization;GO:0008285//negative regulation of cell proliferation;GO:0060306//regulation of membrane repolarization;GO:0003143//embryonic heart tube morphogenesis;GO:0060004//reflex;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0001568//blood vessel development;GO:0006816//calcium ion transport;GO:0009725//response to hormone;GO:0012501//programmed cell death;GO:0034103//regulation of tissue remodeling;GO:0051480//regulation of cytosolic calcium ion concentration gi|33286888|gb|AAH55375.1|/0/Gja1 protein [Mus musculus] 69769 1122 1.426666667 2.506666667 0.813121865 Up 0.506920155 Tnfaip8l2 "tumor necrosis factor, alpha-induced protein 8-like 2" - GO:0044424 - GO:0006954//inflammatory response;GO:0042110//T cell activation gi|674041338|ref|XP_008826471.1|/2.95183e-98/PREDICTED: tumor necrosis factor alpha-induced protein 8-like protein 2 isoform X1 [Nannospalax galili] 81014 2683 8.446666667 10.91333333 0.369637797 Up 0.506290195 Vmn1r58 vomeronasal 1 receptor 58 K04614|1|1e-178|629|mmu:81014|vomeronasal1 receptor GO:0031224//intrinsic component of membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway gi|110431362|ref|NP_109664.2|/9.07945e-178/vomeronasal 1 receptor 58 [Mus musculus] 102635415 556 1.213333333 0.43 -1.496567385 Down 0.506233781 Halr1 Hoxa adjacent long noncoding RNA 1 - - - - - 20893 3113 17.06666667 21.16 0.310158318 Up 0.506205574 Bhlhe40 "basic helix-loop-helix family, member e40" K03729|1|0.0|721|mmu:20893|class B basic helix-loop-helix protein 2 GO:0031981//nuclear lumen "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0046983//protein dimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0042802//identical protein binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0043425//bHLH transcription factor binding" GO:0048731//system development;GO:0009605//response to external stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0048167//regulation of synaptic plasticity;GO:0009648//photoperiodism;GO:0044092//negative regulation of molecular function;GO:0007623//circadian rhythm gi|6755680|ref|NP_035628.1|/0/class E basic helix-loop-helix protein 40 [Mus musculus] 14732 3852 20.73666667 16.68333333 -0.313776437 Down 0.505754259 Gpam "glycerol-3-phosphate acyltransferase, mitochondrial" K00629|1|0.0|1618|mmu:14732|glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15] GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane GO:0008374//O-acyltransferase activity GO:0006732;GO:0046341//CDP-diacylglycerol metabolic process;GO:0006924//activation-induced cell death of T cells;GO:0032868//response to insulin;GO:0055088//lipid homeostasis;GO:0042102//positive regulation of T cell proliferation;GO:0001817//regulation of cytokine production;GO:0002252;GO:0010038//response to metal ion;GO:0032787//monocarboxylic acid metabolic process;GO:0009746;GO:0055081//anion homeostasis;GO:0009991//response to extracellular stimulus;GO:0035264//multicellular organism growth;GO:0010866//regulation of triglyceride biosynthetic process;GO:0032623//interleukin-2 production gi|50510989|dbj|BAD32480.1|/0/mKIAA1560 protein [Mus musculus] 15122 569 306.1366667 363.9733333 0.249656905 Up 0.504917447 Hba-a1 "hemoglobin alpha, adult chain 1" K13822|1|3e-77|289|mmu:110257|hemoglobin subunit alpha GO:0043234//protein complex;GO:0015935//small ribosomal subunit GO:0046906//tetrapyrrole binding;GO:0022892//substrate-specific transporter activity;GO:0046914//transition metal ion binding;GO:0036094//small molecule binding GO:0015669;GO:0051259//protein oligomerization;GO:0000302//response to reactive oxygen species;GO:0008219//cell death;GO:0043009//chordate embryonic development;GO:0008217//regulation of blood pressure;GO:0019233//sensory perception of pain;GO:0030218//erythrocyte differentiation;GO:0042743//hydrogen peroxide metabolic process "gi|145301549|ref|NP_001077424.1|/2.31024e-76/hemoglobin alpha, adult chain 2 [Mus musculus]" 100036523 2620 5.586666667 3.99 -0.485598997 Down 0.504785814 Gm16982 "predicted gene, 16982" K11824|1|2e-21|107|phd:102316648|AP-2 complex subunit alpha - - - "gi|148686171|gb|EDL18118.1|/2.56946e-68/mCG145965, partial [Mus musculus]" 319278 1683 6.31 8.373333333 0.408162053 Up 0.504767009 A230050P20Rik RIKEN cDNA A230050P20 gene K03903|1|2e-10|69.7|fab:101812736|fibrinogen alpha chain - - - gi|28316794|ref|NP_783618.1|/1.50453e-145/UPF0515 protein C19orf66 homolog [Mus musculus] 66241 1460 9.036666667 11.6 0.360262193 Up 0.504550754 Tmem9 transmembrane protein 9 K06013|1|3e-14|82.4|hro:HELRODRAFT_193946|STE24 endopeptidase [EC:3.4.24.84] GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0005770//late endosome;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0005770//late endosome;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0005770//late endosome - GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization gi|13384842|ref|NP_079715.1|/3.92395e-91/transmembrane protein 9 precursor [Mus musculus] 68011 393 14.11 17.60666667 0.319403813 Up 0.504513145 Snrpg small nuclear ribonucleoprotein polypeptide G K11099|1|1e-36|153|pale:102888154|small nuclear ribonucleoprotein G GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding "GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter" gi|4507133|ref|NP_003087.1|/9.13249e-36/small nuclear ribonucleoprotein G isoform a [Homo sapiens] 71371 4494 2.926666667 1.776666667 -0.720085407 Down 0.504240475 Arid5b AT rich interactive domain 5B (MRF1-like) K07874|1|9e-14|82.8|bmor:101744501|Ras-related protein Rab-1A;K06676|3|2e-13|81.3|gfr:102034316|condensin complex subunit 2 - - - gi|74136557|ref|NP_076087.2|/0/AT-rich interactive domain-containing protein 5B [Mus musculus] 14867 1152 1.89 3.063333333 0.696716126 Up 0.504221671 Gstm6 "glutathione S-transferase, mu 6" K00799|1|2e-118|427|mmu:14867|glutathione S-transferase [EC:2.5.1.18] GO:0044424 GO:0003824//catalytic activity - gi|113680506|ref|NP_032210.3|/1.72501e-117/glutathione S-transferase Mu 6 [Mus musculus] 22177 586 12.6 15.80333333 0.326805159 Up 0.504118244 Tyrobp TYRO protein tyrosine kinase binding protein K07992|1|3e-59|229|mmu:22177|TYRO protein tyrosine kinase binding protein GO:0031224//intrinsic component of membrane "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0004871//signal transducer activity;GO:0005515//protein binding" GO:0007166//cell surface receptor signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0002275//myeloid cell activation involved in immune response;GO:0036035//osteoclast development gi|6755915|ref|NP_035792.1|/1.80709e-58/TYRO protein tyrosine kinase-binding protein precursor [Mus musculus] 16450 4054 15.57 12.38333333 -0.330369234 Down 0.503949001 Jag2 jagged 2 K06052|1|0.0|2559|mmu:16450|jagged GO:0016021//integral component of membrane;GO:0044444//cytoplasmic part GO:0005102//receptor binding;GO:0046872//metal ion binding GO:0007166//cell surface receptor signaling pathway;GO:0007155//cell adhesion;GO:0007417//central nervous system development;GO:0045165//cell fate commitment;GO:0008283//cell proliferation;GO:0042476//odontogenesis;GO:0035108//limb morphogenesis;GO:0044267//cellular protein metabolic process;GO:0008406//gonad development;GO:0006915//apoptotic process;GO:0043009//chordate embryonic development;GO:0002009//morphogenesis of an epithelium;GO:0033077//T cell differentiation in thymus;GO:0048232//male gamete generation;GO:0006950//response to stress;GO:0016477//cell migration;GO:0042491//auditory receptor cell differentiation;GO:0003008 gi|146134329|ref|NP_034718.2|/0/protein jagged-2 precursor [Mus musculus] 70082 1200 9.926666667 12.63333333 0.347854094 Up 0.503460077 Lysmd2 "LysM, putative peptidoglycan-binding, domain containing 2" - - - - gi|564364558|ref|XP_006243467.1|/2.52638e-74/PREDICTED: lysM and putative peptidoglycan-binding domain-containing protein 2 isoform X1 [Rattus norvegicus] 240185 6748 17.37333333 13.92 -0.319715372 Down 0.503413066 9430020K01Rik RIKEN cDNA 9430020K01 gene - GO:0030054//cell junction - GO:0022610 gi|126506316|ref|NP_001075432.1|/0/junctional protein associated with coronary artery disease [Mus musculus] 21961 9919.28 273.3166667 230.1333333 -0.248103473 Down 0.503366054 Tns1 tensin 1 K18080|1|0.0|3480|mmu:21961|tensin - - - gi|582117511|ref|NP_001276824.1|/0/tensin 1 isoform b [Mus musculus] 68802 5246 74.93333333 62.45333333 -0.262829055 Down 0.503140396 Mypn myopalladin K19875|1|2e-66|257|shr:100920508|myotilin - - - gi|60360554|dbj|BAD90521.1|/0/mKIAA4170 protein [Mus musculus] 100165 864 12.32333333 15.47 0.328080654 Up 0.502971153 AI507597 expressed sequence AI507597 - GO:0031224//intrinsic component of membrane - - gi|77020279|ref|NP_666099.2|/5.1332e-35/transmembrane protein 82 [Mus musculus] 19428 1039 3.036666667 1.873333333 -0.696880924 Down 0.502736094 Rasl2-9 "RAS-like, family 2, locus 9" K07936|1|1e-110|401|mmu:19428|GTP-binding nuclear protein Ran GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0005635//nuclear envelope;GO:0048770;GO:0044427 GO:0035258//steroid hormone receptor binding;GO:0003712//transcription cofactor activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 "GO:0007010//cytoskeleton organization;GO:0006351//transcription, DNA-templated;GO:0000087//mitotic M phase;GO:0031503//protein complex localization;GO:0009154//purine ribonucleotide catabolic process;GO:0051169//nuclear transport;GO:0006886//intracellular protein transport;GO:0043393//regulation of protein binding;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0007281//germ cell development;GO:0050658//RNA transport;GO:0035556//intracellular signal transduction" "gi|29612666|gb|AAH49619.1|/2.88905e-113/similar to RAS-like, family 2, locus 9, partial [Mus musculus]" 100217450 126 0.01 0.46 5.523561956 Up 0.502670277 Snora47 "small nucleolar RNA, H/ACA box 47" - - - - - 66355 1584 61.01666667 73.10666667 0.260799605 Up 0.502576253 Gmpr guanosine monophosphate reductase K00364|1|0.0|665|mmu:66355|GMP reductase [EC:1.7.1.7] - "GO:0043169//cation binding;GO:0016657//oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor" GO:0006753//nucleoside phosphate metabolic process;GO:0006950//response to stress gi|17975500|ref|NP_079784.1|/0/GMP reductase 1 [Mus musculus] 68523 680 61.03333333 73.11333333 0.260537142 Up 0.502566851 Fam96b "family with sequence similarity 96, member B" K11660|1|3e-37|157|tsp:Tsp_09343|metastasis-associated protein MTA;K03927|2|2e-06|54.7|hgl:101702623|carboxylesterase 2 [EC:3.1.1.1 3.1.1.84 3.1.1.56] GO:0005819//spindle;GO:0043231//intracellular membrane-bounded organelle - GO:0044763 gi|524957514|ref|XP_005078719.1|/9.23914e-80/PREDICTED: mitotic spindle-associated MMXD complex subunit MIP18 [Mesocricetus auratus] 228812 1621 16.12666667 19.96666667 0.308145234 Up 0.502454022 Pigu "phosphatidylinositol glycan anchor biosynthesis, class U" "K05293|1|0.0|833|mmu:228812|phosphatidylinositol glycan, class U" GO:0030176//integral component of endoplasmic reticulum membrane GO:0035091//phosphatidylinositol binding;GO:0016787//hydrolase activity GO:0007259//JAK-STAT cascade;GO:0006497//protein lipidation "gi|148674170|gb|EDL06117.1|/0/CDC91 cell division cycle 91-like 1 (S. cerevisiae), partial [Mus musculus]" 67893 1791 15.91333333 19.75 0.311616588 Up 0.502454022 Tmem86a transmembrane protein 86A K18575|1|5e-28|128|oaa:100076472|alkenylglycerophosphocholine/alkenylglycerophosphoethanolamine hydrolase [EC:3.3.2.2 3.3.2.5] GO:0031224//intrinsic component of membrane - - gi|21312738|ref|NP_080712.1|/5.8423e-119/lysoplasmalogenase-like protein TMEM86A [Mus musculus] 68001 1163 15.79 19.60666667 0.312333112 Up 0.502143744 1110004E09Rik RIKEN cDNA 1110004E09 gene - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - - gi|255683337|ref|NP_080778.2|/4.1264e-159/UPF0769 protein C21orf59 homolog [Mus musculus] 71743 2153 6.863333333 9.013333333 0.393151322 Up 0.502040317 Coasy Coenzyme A synthase K02318|1|0.0|1010|mmu:71743|phosphopantetheine adenylyltransferase / dephospho-CoA kinase [EC:2.7.7.3 2.7.1.24] GO:0031981//nuclear lumen GO:0032550;GO:0070566//adenylyltransferase activity;GO:0016301//kinase activity GO:0009108//coenzyme biosynthetic process;GO:0006796//phosphate-containing compound metabolic process "gi|148671931|gb|EDL03878.1|/0/Coenzyme A synthase, isoform CRA_a, partial [Mus musculus]" 14137 3717 16.15333333 19.96333333 0.305520728 Up 0.50201211 Fdft1 farnesyl diphosphate farnesyl transferase 1 K00801|1|0.0|845|mmu:14137|farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0004311//farnesyltranstransferase activity GO:0006694//steroid biosynthetic process;GO:0006720//isoprenoid metabolic process;GO:0006644//phospholipid metabolic process;GO:0008203//cholesterol metabolic process gi|34328173|ref|NP_034321.2|/0/squalene synthase [Mus musculus] 20638 1121 60.87666667 72.65333333 0.255139625 Up 0.501946294 Snrpb small nuclear ribonucleoprotein B K11086|1|1e-68|262|shr:100925653|small nuclear ribonucleoprotein B and B' GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0003723//RNA binding;GO:0005515//protein binding "GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter" gi|5870130|gb|AAD54489.1|/3.27036e-81/small nuclear ribonucleoprotein B' [Homo sapiens] 70445 2660 12.40333333 9.75 -0.347253766 Down 0.501607808 Cd248 "CD248 antigen, endosialin" "K06706|1|0.0|1397|mmu:70445|CD248 antigen, endosialin" GO:0031012//extracellular matrix;GO:0031224//intrinsic component of membrane;GO:0044424 GO:0005488//binding GO:0048870//cell motility;GO:0008283//cell proliferation;GO:0009653//anatomical structure morphogenesis;GO:0048534//hematopoietic or lymphoid organ development;GO:0043065//positive regulation of apoptotic process gi|16923944|ref|NP_473383.1|/0/endosialin precursor [Mus musculus] 69754 1886 9.566666667 12.21333333 0.352368767 Up 0.501607808 Fbxo7 F-box protein 7 K10293|1|0.0|886|mmu:69754|F-box protein 7 - - - - 18245 1091.88 166.4766667 197.5766667 0.247092594 Up 0.501353943 Oaz1 ornithine decarboxylase antizyme 1 K16548|1|7e-96|276|tup:102496602|ornithine decarboxylase antizyme 1 - GO:0005488//binding;GO:0004857//enzyme inhibitor activity;GO:0005488//binding;GO:0004857//enzyme inhibitor activity GO:0044092//negative regulation of molecular function;GO:0006576//cellular biogenic amine metabolic process;GO:0044092//negative regulation of molecular function;GO:0006576//cellular biogenic amine metabolic process gi|1924976|gb|AAB96330.1|/1.9895e-124/ornithine decarboxylase antizyme [Mus musculus] 14245 5581 67.6 56.26666667 -0.264742748 Down 0.501250517 Lpin1 lipin 1 K15728|1|0.0|1664|mmu:14245|phosphatidate phosphatase LPIN [EC:3.1.3.4] GO:0031966//mitochondrial membrane;GO:0005635//nuclear envelope;GO:0043234//protein complex;GO:0031966//mitochondrial membrane;GO:0005635//nuclear envelope;GO:0043234//protein complex;GO:0031966//mitochondrial membrane;GO:0005635//nuclear envelope;GO:0043234//protein complex GO:0005102//receptor binding;GO:0003712//transcription cofactor activity;GO:0016791//phosphatase activity;GO:0019899//enzyme binding;GO:0008134//transcription factor binding;GO:0005102//receptor binding;GO:0003712//transcription cofactor activity;GO:0016791//phosphatase activity;GO:0019899//enzyme binding;GO:0008134//transcription factor binding;GO:0005102//receptor binding;GO:0003712//transcription cofactor activity;GO:0016791//phosphatase activity;GO:0019899//enzyme binding;GO:0008134//transcription factor binding GO:0032868//response to insulin;GO:0006366//transcription from RNA polymerase II promoter;GO:0016575//histone deacetylation;GO:0006796//phosphate-containing compound metabolic process;GO:0045444//fat cell differentiation;GO:0030036//actin cytoskeleton organization;GO:0006631//fatty acid metabolic process;GO:0030030//cell projection organization;GO:0009887//organ morphogenesis;GO:0007005//mitochondrion organization;GO:0006641//triglyceride metabolic process;GO:0032868//response to insulin;GO:0006366//transcription from RNA polymerase II promoter;GO:0016575//histone deacetylation;GO:0006796//phosphate-containing compound metabolic process;GO:0045444//fat cell differentiation;GO:0030036//actin cytoskeleton organization;GO:0006631//fatty acid metabolic process;GO:0030030//cell projection organization;GO:0007005//mitochondrion organization;GO:0006641//triglyceride metabolic process;GO:0032868//response to insulin;GO:0006366//transcription from RNA polymerase II promoter;GO:0016575//histone deacetylation;GO:0006796//phosphate-containing compound metabolic process;GO:0045444//fat cell differentiation;GO:0030036//actin cytoskeleton organization;GO:0006631//fatty acid metabolic process;GO:0030030//cell projection organization;GO:0007005//mitochondrion organization;GO:0006641//triglyceride metabolic process gi|568977524|ref|XP_006515045.1|/0/PREDICTED: phosphatidate phosphatase LPIN1 isoform X7 [Mus musculus] 170942 796 56.72333333 68 0.261592432 Up 0.501090677 Erdr1 erythroid differentiation regulator 1 - - - GO:0016477//cell migration;GO:0008283//cell proliferation;GO:0019827//stem cell population maintenance gi|28193093|emb|CAD62281.1|/4.04457e-81/erythroid differentiation regulator [Mus musculus] 12444 5772 16.57666667 13.24666667 -0.323524559 Down 0.501081274 Ccnd2 cyclin D2 K10151|1|2e-156|557|mmu:12444|cyclin D2 GO:0031981//nuclear lumen;GO:0044427;GO:0005635//nuclear envelope;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0019900//kinase binding GO:0032868//response to insulin;GO:0044772//mitotic cell cycle phase transition;GO:0008585//female gonad development;GO:0046683//response to organophosphorus;GO:0043627//response to estrogen;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0008284//positive regulation of cell proliferation;GO:0048232//male gamete generation;GO:0097305//response to alcohol;GO:0030182//neuron differentiation gi|6753310|ref|NP_033959.1|/1.3397e-155/G1/S-specific cyclin-D2 [Mus musculus] 102465564 64 28.21333333 34.16666667 0.276212377 Up 0.50102486 Mir6935 microRNA 6935 - - - - - 654804 1028 7.333333333 9.56 0.3825415 Up 0.500959043 4732471J01Rik RIKEN cDNA 4732471J01 gene K07188|1|1e-40|169|mmu:16890|hormone-sensitive lipase [EC:3.1.1.79] - - - - 66871 1087.64 12.07666667 15.14 0.3261429 Up 0.500705179 Cpne8 copine VIII K11348|1|6e-30|135|apla:101800649|bromodomain and PHD finger-containing protein 1;K06491|3|3e-11|73.9|cin:100183448|neural cell adhesion molecule;K15290|4|8e-09|65.9|cel:CELE_F31E8.2|synaptotagmin-1;K19910|5|3e-08|63.9|tca:658788|synaptotagmin-10 - - - gi|76563928|ref|NP_001029023.1|/9.85592e-54/copine-8 isoform 2 [Mus musculus] 64294 2024 37.62666667 45.21666667 0.265099155 Up 0.500601753 Itm2c integral membrane protein 2C K18265|1|1e-121|439|mcc:711245|integral membrane protein 2C GO:0031224//intrinsic component of membrane;GO:0005764//lysosome GO:0042277//peptide binding;GO:0032550 GO:0043068//positive regulation of programmed cell death;GO:0010975//regulation of neuron projection development gi|297265084|ref|XP_001112946.2|/9.50618e-121/PREDICTED: integral membrane protein 2C [Macaca mulatta] 13047 3737.76 36.32666667 43.92 0.273849064 Up 0.500601753 Cux1 cut-like homeobox 1 K09313|1|0.0|1238|tup:102472150|homeobox protein cut-like GO:0031981//nuclear lumen;GO:0031228//intrinsic component of Golgi membrane;GO:0031981//nuclear lumen;GO:0031228//intrinsic component of Golgi membrane;GO:0031981//nuclear lumen;GO:0031228//intrinsic component of Golgi membrane GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0060113//inner ear receptor cell differentiation;GO:0030323//respiratory tube development;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0060113//inner ear receptor cell differentiation;GO:0030323//respiratory tube development;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0060113//inner ear receptor cell differentiation;GO:0030323//respiratory tube development "gi|148687364|gb|EDL19311.1|/0/cut-like 1 (Drosophila), isoform CRA_d, partial [Mus musculus]" 69922 1906 2.776666667 4.113333333 0.566953994 Up 0.500479522 Vrk2 vaccinia related kinase 2 K08816|1|0.0|918|mmu:69922|vaccinia related kinase [EC:2.7.11.1] GO:0044425;GO:0031090//organelle membrane;GO:0005740//mitochondrial envelope;GO:0044425;GO:0031090//organelle membrane;GO:0005740//mitochondrial envelope GO:0005488//binding;GO:0004672//protein kinase activity;GO:0005488//binding;GO:0004672//protein kinase activity GO:0006979//response to oxidative stress;GO:0006468//protein phosphorylation;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0000165//MAPK cascade;GO:0006979//response to oxidative stress;GO:0006468//protein phosphorylation;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0000165//MAPK cascade gi|356995837|ref|NP_001239376.1|/0/serine/threonine-protein kinase VRK2 isoform 2 [Mus musculus] 108902 2035 27.29333333 33.17 0.28133041 Up 0.50043251 B4gat1 "beta-1,4-glucuronyltransferase 1" "K00741|1|0.0|769|mmu:108902|N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.149]" GO:0031228//intrinsic component of Golgi membrane GO:0008375//acetylglucosaminyltransferase activity GO:0007606//sensory perception of chemical stimulus;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0006935//chemotaxis;GO:0006464//cellular protein modification process "gi|30039682|ref|NP_780592.1|/0/beta-1,4-glucuronyltransferase 1 [Mus musculus]" 27279 974.19 44.86333333 37.31 -0.265974456 Down 0.500423107 Tnfrsf12a "tumor necrosis factor receptor superfamily, member 12a" K05149|1|6e-52|206|mmu:27279|tumor necrosis factor receptor superfamily member 12A GO:0031252//cell leading edge;GO:0016020//membrane;GO:0016020//membrane;GO:0044464 GO:0005488//binding GO:0012502//induction of programmed cell death;GO:0048869//cellular developmental process;GO:0022610;GO:0097191//extrinsic apoptotic signaling pathway;GO:0030307//positive regulation of cell growth;GO:0006929//substrate-dependent cell migration;GO:0042981//regulation of apoptotic process;GO:0048522;GO:0032502//developmental process "gi|148690313|gb|EDL22260.1|/1.16674e-34/tumor necrosis factor receptor superfamily, member 12a, isoform CRA_a [Mus musculus]" 14261 2349 43.67 36.14666667 -0.272779919 Down 0.5003949 Fmo1 flavin containing monooxygenase 1 K00485|1|0.0|1052|mmu:14261|dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8] GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane "GO:0000166//nucleotide binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen" GO:0055114//oxidation-reduction process;GO:0019748//secondary metabolic process;GO:0002237//response to molecule of bacterial origin;GO:0044237//cellular metabolic process;GO:0006950//response to stress gi|6753890|ref|NP_034361.1|/0/dimethylaniline monooxygenase [N-oxide-forming] 1 [Mus musculus] 29858 1316 17.86666667 22.02333333 0.301762344 Up 0.500310279 Pmm1 phosphomannomutase 1 K17497|1|1e-148|528|mmu:29858|phosphomannomutase [EC:5.4.2.8] GO:0044297//cell body;GO:0044424;GO:0044297//cell body;GO:0044424;GO:0044297//cell body;GO:0044424 "GO:0016868//intramolecular transferase activity, phosphotransferases;GO:0043169//cation binding;GO:0016868//intramolecular transferase activity, phosphotransferases;GO:0043169//cation binding;GO:0016868//intramolecular transferase activity, phosphotransferases;GO:0043169//cation binding" GO:0006013//mannose metabolic process;GO:0006013//mannose metabolic process;GO:0006013//mannose metabolic process gi|530677960|ref|NP_001268969.1|/4.33494e-113/phosphomannomutase 1 isoform 2 [Mus musculus] 227696 1332.12 44.37 36.91333333 -0.265442532 Down 0.500188048 Phyhd1 phytanoyl-CoA dioxygenase domain containing 1 K00477|1|7e-140|499|ptg:102969046|phytanoyl-CoA hydroxylase [EC:1.14.11.18];K18741|3|1e-60|236|dpe:Dper_GL23824|protein nanos 1 - "GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0043169//cation binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0043169//cation binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0043169//cation binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0043169//cation binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0043169//cation binding" GO:0044710;GO:0044710;GO:0044710;GO:0044710;GO:0044710 gi|26986561|ref|NP_758471.1|/0/phytanoyl-CoA dioxygenase domain-containing protein 1 isoform 1 [Mus musculus] 67674 1047 36.07333333 43.50333333 0.270193207 Up 0.500075219 Trmt112 tRNA methyltransferase 11-2 K15448|1|9e-69|262|cge:100758109|multifunctional methyltransferase subunit TRM112 GO:0032991//macromolecular complex;GO:0032991//macromolecular complex - GO:0006479//protein methylation;GO:0006479//protein methylation gi|354498436|ref|XP_003511321.1|/7.04424e-68/PREDICTED: tRNA methyltransferase 112 homolog [Cricetulus griseus] 242687 4088 33.47333333 27.65333333 -0.275558831 Down 0.499990598 Wasf2 "WAS protein family, member 2" "K05748|1|2e-144|516|mmu:242687|WAS protein family, member 2" GO:0043232;GO:0031252//cell leading edge;GO:0005768//endosome GO:0008092//cytoskeletal protein binding GO:0016477//cell migration;GO:0016192//vesicle-mediated transport;GO:0007265//Ras protein signal transduction;GO:0048858//cell projection morphogenesis;GO:0007010//cytoskeleton organization;GO:0030219//megakaryocyte differentiation;GO:0030031//cell projection assembly gi|74182504|dbj|BAE42873.1|/1.80721e-143/unnamed protein product [Mus musculus] 78943 3976 2.726666667 1.63 -0.742266378 Down 0.499934183 Ern1 endoplasmic reticulum (ER) to nucleus signalling 1 K08852|1|0.0|1781|mmu:78943|serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-] GO:0019866//organelle inner membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0004519//endonuclease activity "GO:0006351//transcription, DNA-templated;GO:0006396//RNA processing;GO:0006468//protein phosphorylation;GO:0009967//positive regulation of signal transduction;GO:0022402//cell cycle process;GO:0012502//induction of programmed cell death;GO:0030968//endoplasmic reticulum unfolded protein response" gi|13249351|ref|NP_076402.1|/0/serine/threonine-protein kinase/endoribonuclease IRE1 precursor [Mus musculus] 433766 1886 137.19 163.14 0.249935232 Up 0.499840159 Trim63 tripartite motif-containing 63 K10655|1|0.0|654|mmu:433766|tripartite motif-containing protein 63 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0006511//ubiquitin-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation;GO:0031960//response to corticosteroid;GO:0034097//response to cytokine;GO:0010467//gene expression;GO:0014891//striated muscle atrophy gi|223461997|gb|AAI47667.1|/0/Tripartite motif-containing 63 [Mus musculus] 18102 1235 8.546666667 10.97666667 0.36100625 Up 0.499821355 Nme1 NME/NM23 nucleoside diphosphate kinase 1 K00940|1|2e-83|311|mmu:18102|nucleoside-diphosphate kinase [EC:2.7.4.6] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part "GO:0046872//metal ion binding;GO:0019900//kinase binding;GO:0043566//structure-specific DNA binding;GO:0032403//protein complex binding;GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0015631//tubulin binding;GO:0004518//nuclease activity;GO:0000976//transcription regulatory region sequence-specific DNA binding" GO:0010467//gene expression;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0048732//gland development;GO:0010243//response to organonitrogen compound;GO:0021543//pallium development;GO:0001678//cellular glucose homeostasis;GO:0007589//body fluid secretion;GO:0009132//nucleoside diphosphate metabolic process;GO:0010975//regulation of neuron projection development;GO:0046683//response to organophosphorus;GO:0048545//response to steroid hormone;GO:0009209;GO:0009152//purine ribonucleotide biosynthetic process;GO:0051099//positive regulation of binding;GO:0016192//vesicle-mediated transport;GO:0002573//myeloid leukocyte differentiation;GO:0042493//response to drug;GO:0070542//response to fatty acid "gi|387496|gb|AAA39826.1|/1.3907e-91/tumor metastatic process-associated protein NM23, partial [Mus musculus]" 66939 2600 8.563333333 10.99333333 0.360384509 Up 0.499821355 Aagab alpha- and gamma-adaptin binding protein - GO:0044444//cytoplasmic part - GO:0045184//establishment of protein localization gi|20071057|gb|AAH27311.1|/3.24406e-156/RIKEN cDNA 2310007F21 gene [Mus musculus] 15270 1414 7.983333333 10.29333333 0.366647097 Up 0.499727331 H2afx "H2A histone family, member X" K11251|1|9e-61|236|mmu:15270|histone H2A - - - - 13870 1133.96 35.79666667 43.15333333 0.269646751 Up 0.499727331 Ercc1 "excision repair cross-complementing rodent repair deficiency, complementation group 1" K10849|1|1e-161|571|mmu:13870|DNA excision repair protein ERCC-1 "GO:0000781//chromosome, telomeric region;GO:0005667//transcription factor complex;GO:0000781//chromosome, telomeric region;GO:0005667//transcription factor complex" GO:0001091;GO:0004520//endodeoxyribonuclease activity;GO:0043566//structure-specific DNA binding;GO:0001091;GO:0004520//endodeoxyribonuclease activity;GO:0043566//structure-specific DNA binding "GO:0040007//growth;GO:0034285;GO:0009791//post-embryonic development;GO:0008406//gonad development;GO:0007569//cell aging;GO:0006915//apoptotic process;GO:0009411//response to UV;GO:0033683//nucleotide-excision repair, DNA incision;GO:0009790//embryo development;GO:0000723//telomere maintenance;GO:0030154//cell differentiation;GO:0007292//female gamete generation;GO:0048232//male gamete generation;GO:0010212//response to ionizing radiation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0002204//somatic recombination of immunoglobulin genes involved in immune response;GO:0031667//response to nutrient levels;GO:0040007//growth;GO:0034285;GO:0009791//post-embryonic development;GO:0008406//gonad development;GO:0007569//cell aging;GO:0006915//apoptotic process;GO:0009411//response to UV;GO:0033683//nucleotide-excision repair, DNA incision;GO:0009790//embryo development;GO:0000723//telomere maintenance;GO:0030154//cell differentiation;GO:0007292//female gamete generation;GO:0048232//male gamete generation;GO:0010212//response to ionizing radiation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0002204//somatic recombination of immunoglobulin genes involved in immune response;GO:0031667//response to nutrient levels" gi|187960071|ref|NP_001120796.1|/2.36787e-123/DNA excision repair protein ERCC-1 isoform b [Mus musculus] 218832 4683 4.953333333 3.483333333 -0.507931174 Down 0.499661514 Polr3a polymerase (RNA) III (DNA directed) polypeptide A K03018|1|0.0|2734|mmu:218832|DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6] - GO:0034062//RNA polymerase activity GO:0032481//positive regulation of type I interferon production;GO:0006952//defense response;GO:0010467//gene expression gi|124486963|ref|NP_001074716.1|/0/DNA-directed RNA polymerase III subunit RPC1 [Mus musculus] 72549 1686 2.83 4.183333333 0.563850905 Up 0.4996051 Reep4 receptor accessory protein 4 K17338|1|5e-131|470|mmu:72549|receptor expression-enhancing protein 1/2/3/4 GO:0031224//intrinsic component of membrane - - gi|30725847|ref|NP_850919.1|/3.99697e-130/receptor expression-enhancing protein 4 precursor [Mus musculus] 434215 3817 7.366666667 5.496666667 -0.422454971 Down 0.49940765 Lrrc32 leucine rich repeat containing 32 "K01384|1|2e-35|154|amj:102558673|wingless-type MMTV integration site family, member 11;K17256|3|2e-33|147|oaa:100091187|insulin-like growth factor-binding protein complex acid labile subunit" - - - - 73287 1238 16.15666667 12.90333333 -0.324385775 Down 0.499351235 1700040L02Rik RIKEN cDNA 1700040L02 gene - - - - gi|28077019|ref|NP_082767.1|/1.36391e-171/uncharacterized protein C10orf107 homolog [Mus musculus] 56430 5714.84 42.66333333 35.45333333 -0.267075413 Down 0.499069164 Clip1 CAP-GLY domain containing linker protein 1 K10421|1|0.0|2315|mmu:56430|CAP-Gly domain-containing linker protein 1 GO:0005815//microtubule organizing center;GO:0005874//microtubule;GO:0031982//vesicle;GO:0005815//microtubule organizing center;GO:0005874//microtubule;GO:0031982//vesicle GO:0008017//microtubule binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0008017//microtubule binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0031112;GO:0051234//establishment of localization;GO:0031112;GO:0051234//establishment of localization gi|23821025|ref|NP_062739.2|/0/CAP-Gly domain-containing linker protein 1 isoform a [Mus musculus] 330189 1860 4.886666667 6.633333333 0.440883327 Up 0.499069164 Tmem120b transmembrane protein 120B K14574|1|1e-62|243|spu:588956|ribosome maturation protein SDO1 - - - - 319183 429 0.453333333 0.01 -5.502500341 Down 0.498458009 Hist1h2bj "histone cluster 1, H2bj" K11252|1|3e-44|178|pps:100984497|histone H2B GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|355558373|gb|EHH15153.1|/1.55802e-43/hypothetical protein EGK_01208 [Macaca mulatta] 22320 786 49.15333333 58.92333333 0.261549791 Up 0.497743428 Vamp8 vesicle-associated membrane protein 8 K08512|1|2e-39|164|mmu:22320|vesicle-associated membrane protein 8 "GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0043234//protein complex;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005770//late endosome" GO:0000149//SNARE binding GO:0006897//endocytosis;GO:0065003 "gi|148666563|gb|EDK98979.1|/2.30655e-65/vesicle-associated membrane protein 8, isoform CRA_a, partial [Mus musculus]" 328232 6654 11.78666667 9.26 -0.348071675 Down 0.497724623 Gfod1 glucose-fructose oxidoreductase domain containing 1 K00078|1|1e-08|66.6|dpe:Dper_GL19398|dihydrodiol dehydrogenase / D-xylose 1-dehydrogenase (NADP) [EC:1.3.1.20 1.1.1.179] - GO:0036094//small molecule binding;GO:0003824//catalytic activity GO:0044710 gi|85701893|ref|NP_001028571.1|/0/glucose-fructose oxidoreductase domain-containing protein 1 precursor [Mus musculus] 69684 1346 25.62 31.13 0.281035101 Up 0.497724623 Aarsd1 alanyl-tRNA synthetase domain containing 1 K07050|1|0.0|770|mmu:69684|misacylated tRNA(Ala) deacylase [EC:3.1.1.-] GO:0044424 GO:0043169//cation binding;GO:0032550;GO:0002161//aminoacyl-tRNA editing activity;GO:0004812//aminoacyl-tRNA ligase activity GO:0006448//regulation of translational elongation;GO:0006418//tRNA aminoacylation for protein translation gi|21450213|ref|NP_659078.1|/0/alanyl-tRNA editing protein Aarsd1 [Mus musculus] 235633 5106 10.03666667 7.776666667 -0.368056401 Down 0.497545978 Als2cl ALS2 C-terminal like K04575|1|2e-139|500|mcf:101925534|amyotrophic lateral sclerosis 2 protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity;GO:0017016//Ras GTPase binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity;GO:0017016//Ras GTPase binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity;GO:0017016//Ras GTPase binding GO:0007266//Rho protein signal transduction;GO:0033036;GO:0006996//organelle organization;GO:0007266//Rho protein signal transduction;GO:0033036;GO:0006996//organelle organization;GO:0007266//Rho protein signal transduction;GO:0033036;GO:0006996//organelle organization gi|225690620|ref|NP_666340.3|/0/ALS2 C-terminal-like protein [Mus musculus] 20257 1904 5.776666667 4.183333333 -0.46558429 Down 0.497414344 Stmn2 stathmin-like 2 K04381|1|1e-47|194|ccw:104694638|stathmin GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0044444//cytoplasmic part GO:0005488//binding GO:0007019//microtubule depolymerization;GO:0031111//negative regulation of microtubule polymerization or depolymerization;GO:0010975//regulation of neuron projection development gi|12850126|dbj|BAB28602.1|/4.16056e-107/unnamed protein product [Mus musculus] 83675 3111 4.276666667 2.923333333 -0.548872423 Down 0.497254504 Bicc1 BicC family RNA binding protein 1 K18756|1|0.0|1651|mmu:83675|protein bicaudal C - - - - 72565 4428 24.44 19.94 -0.293578875 Down 0.497010042 Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats K20478|1|1e-33|148|dre:557772|golgin subfamily B member 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0012505//endomembrane system;GO:0043232;GO:0044444//cytoplasmic part - GO:0006974//cellular response to DNA damage stimulus;GO:0006915//apoptotic process;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0006954//inflammatory response;GO:0009416//response to light stimulus;GO:0006979//response to oxidative stress "gi|148694057|gb|EDL26004.1|/0/uveal autoantigen with coiled-coil domains and ankyrin repeats, isoform CRA_c, partial [Mus musculus]" 622459 1152 0.44 1.193333333 1.439421658 Up 0.496991237 Gm12216 predicted gene 12216 - - - - "gi|148701616|gb|EDL33563.1|/1.50083e-36/mCG13775, isoform CRA_b, partial [Mus musculus]" 72503 7554 57.61 48.26 -0.255491342 Down 0.496737373 2610507B11Rik RIKEN cDNA 2610507B11 gene K18263|1|6e-26|124|hgl:101700242|G-protein coupled receptor 98 - - - - 19416 1624 5.823333333 7.74 0.410488364 Up 0.496521118 Rasd1 "RAS, dexamethasone-induced 1" "K07843|1|1e-140|502|cge:103160646|RAS, dexamethasone-induced Ras-related protein 1" - - - - 14129 2589 0.606666667 1.403333333 1.209881783 Up 0.49637068 Fcgr1 "Fc receptor, IgG, high affinity I" K06498|1|0.0|800|mmu:14129|high affinity immunoglobulin gamma Fc receptor I GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0019763//immunoglobulin receptor activity;GO:0019865//immunoglobulin binding GO:0001802;GO:0006909//phagocytosis;GO:0051707//response to other organism;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0038093//Fc receptor signaling pathway;GO:0001794 gi|6753832|ref|NP_034316.1|/0/high affinity immunoglobulin gamma Fc receptor I precursor [Mus musculus] 94089 1366 19.85 24.30333333 0.292015193 Up 0.496361277 Trim7 tripartite motif-containing 7 K12000|1|2e-143|511|mmu:94089|tripartite motif-containing protein 7 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - gi|568976563|ref|XP_006534636.1|/3.64083e-144/PREDICTED: tripartite motif-containing protein 7 isoform X6 [Mus musculus] 21859 4681 113.1666667 94.95666667 -0.253107877 Down 0.49633307 Timp3 tissue inhibitor of metalloproteinase 3 K16866|1|6e-127|458|mmu:21859|metalloproteinase inhibitor 3 GO:0005578//proteinaceous extracellular matrix;GO:0044424 GO:0043169//cation binding;GO:0004866//endopeptidase inhibitor activity GO:0012502//induction of programmed cell death;GO:0009888//tissue development;GO:0001101//response to acid chemical;GO:0048545//response to steroid hormone;GO:0044092//negative regulation of molecular function;GO:0006509//membrane protein ectodomain proteolysis;GO:0050953//sensory perception of light stimulus;GO:0044767//single-organism developmental process;GO:0007399//nervous system development;GO:0009605//response to external stimulus gi|6755793|ref|NP_035725.1|/5.18744e-126/metalloproteinase inhibitor 3 precursor [Mus musculus] 12292 6207.78 3.703333333 5.203333333 0.490611721 Up 0.496323668 Cacna1s "calcium channel, voltage-dependent, L type, alpha 1S subunit" K04857|1|0.0|3406|mmu:12292|voltage-dependent calcium channel L type alpha-1S GO:0034704//calcium channel complex;GO:0042383//sarcolemma;GO:0005783//endoplasmic reticulum;GO:0030017//sarcomere;GO:0034704//calcium channel complex;GO:0042383//sarcolemma;GO:0005783//endoplasmic reticulum;GO:0030017//sarcomere GO:0043169//cation binding;GO:0005245//voltage-gated calcium channel activity;GO:0043169//cation binding;GO:0005245//voltage-gated calcium channel activity GO:0006996//organelle organization;GO:0048741//skeletal muscle fiber development;GO:0000768//syncytium formation by plasma membrane fusion;GO:0006816//calcium ion transport;GO:0014888;GO:0006936//muscle contraction;GO:0006996//organelle organization;GO:0048741//skeletal muscle fiber development;GO:0000768//syncytium formation by plasma membrane fusion;GO:0006816//calcium ion transport;GO:0014888;GO:0006936//muscle contraction gi|189409136|ref|NP_055008.2|/0/voltage-dependent L-type calcium channel subunit alpha-1S isoform 1 [Mus musculus] 69870 1426.78 32.22333333 38.86 0.27018016 Up 0.49617323 Polr3gl polymerase (RNA) III (DNA directed) polypeptide G like K03024|1|4e-65|251|pon:100433086|DNA-directed RNA polymerase III subunit RPC7 - - - "gi|148706949|gb|EDL38896.1|/5.49559e-82/polymerase (RNA) III (DNA directed) polypeptide G like, isoform CRA_b, partial [Mus musculus]" 54137 1403.58 1.28 2.276666667 0.830779268 Up 0.495862951 Acrbp proacrosin binding protein - GO:0031982//vesicle;GO:0031982//vesicle - - gi|188219770|ref|NP_001120812.1|/6.30068e-140/acrosin-binding protein isoform 2 precursor [Mus musculus] 23874 2099.49 24.37666667 29.65 0.282531243 Up 0.495853548 Farsb "phenylalanyl-tRNA synthetase, beta subunit" K01890|1|0.0|1142|mmu:23874|phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0032550;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation gi|31981400|ref|NP_035941.2|/0/phenylalanine--tRNA ligase beta subunit [Mus musculus] 19354 3036 2.48 3.726666667 0.587545662 Up 0.495665501 Rac2 RAS-related C3 botulinum substrate 2 K07860|1|7e-108|394|rno:366957|Ras-related C3 botulinum toxin substrate 2 GO:0016020//membrane;GO:0012505//endomembrane system;GO:0044444//cytoplasmic part GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0007010//cytoskeleton organization;GO:0007599//hemostasis;GO:0042743//hydrogen peroxide metabolic process;GO:0008283//cell proliferation;GO:0022607//cellular component assembly;GO:0007264//small GTPase mediated signal transduction;GO:0006935//chemotaxis;GO:0009154//purine ribonucleotide catabolic process;GO:0019222//regulation of metabolic process;GO:0001775//cell activation;GO:0001894//tissue homeostasis gi|537235276|gb|ERE85167.1|/9.65827e-115/ras-related C3 botulinum toxin substrate 1-like protein [Cricetulus griseus] 243912 1383 1303.353333 1106.033333 -0.236833379 Down 0.495270601 Hspb6 "heat shock protein, alpha-crystallin-related, B6" K09545|1|6e-71|270|mmu:243912|heat shock protein beta-6 GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity;GO:0042802//identical protein binding GO:0050896//response to stimulus;GO:0006936//muscle contraction gi|59958370|ref|NP_001012401.1|/4.62021e-70/heat shock protein beta-6 [Mus musculus] 12831 8420 8.566666667 6.55 -0.387239047 Down 0.495223589 Col5a1 "collagen, type V, alpha 1" "K19721|1|0.0|710|mmu:12831|collagen, type V/XI/XXIV/XXVII, alpha" GO:0005581//collagen trimer GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding GO:0009888//tissue development;GO:0009887//organ morphogenesis;GO:0030198//extracellular matrix organization "gi|148676427|gb|EDL08374.1|/0/procollagen, type V, alpha 1 [Mus musculus]" 76467 1204 45.30666667 54.1 0.255905242 Up 0.495214186 Msrb2 methionine sulfoxide reductase B2 K07305|1|8e-89|329|mmu:76467|peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor" GO:0044267//cellular protein metabolic process;GO:0044710 "gi|21313208|ref|NP_083895.1|/6.84816e-88/methionine-R-sulfoxide reductase B2, mitochondrial precursor [Mus musculus]" 233529 2318 0.766666667 1.606666667 1.067399285 Up 0.495016736 Kctd14 potassium channel tetramerisation domain containing 14 K20131|1|2e-25|120|cmy:102940364|Rab5 GDP/GTP exchange factor - GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity - gi|210033151|ref|NP_001129707.1|/8.01458e-167/BTB/POZ domain-containing protein KCTD14 isoform a [Mus musculus] 319173 468 0.196666667 0.84 2.094636874 Up 0.49495092 Hist1h2af "histone cluster 1, H2af" K11251|1|2e-54|212|cge:100750550|histone H2A;K11253|3|4e-54|211|mdo:100011902|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|30061379|ref|NP_783592.1|/1.66178e-53/histone H2A type 1-F [Mus musculus] 240879 1053 0.956666667 0.28 -1.772589504 Down 0.494791079 Mettl11b methyltransferase like 11B K19579|1|3e-163|576|mmu:240879|protein N-terminal monomethyltransferase [EC:2.1.1.299] - GO:0016741 GO:0008152//metabolic process gi|984111714|ref|XP_015347333.1|/3.09539e-163/PREDICTED: alpha N-terminal protein methyltransferase 1B [Marmota marmota marmota] 319189 493 0.316666667 1.01 1.673318375 Up 0.494781677 Hist2h2bb "histone cluster 2, H2bb" K11252|1|4e-44|178|cge:100761268|histone H2B;K11253|2|5e-44|178|dre:100329423|histone H3 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|431892245|gb|ELK02685.1|/4.15145e-44/histone H2B type 1 [Pteropus alecto] 13804 1032 44.29 52.86666667 0.255377368 Up 0.494499605 Endog endonuclease G "K01173|1|6e-135|482|mmu:13804|endonuclease G, mitochondrial" GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0097159//organic cyclic compound binding;GO:0004518//nuclease activity "GO:0009636//response to toxic substance;GO:0006915//apoptotic process;GO:0043009//chordate embryonic development;GO:0000737//DNA catabolic process, endonucleolytic;GO:0034097//response to cytokine" "gi|6679647|ref|NP_031957.1|/5.01464e-134/endonuclease G, mitochondrial precursor [Mus musculus]" 56437 1577 97.25666667 81.90333333 -0.247874978 Down 0.494217534 Rrad Ras-related associated with diabetes K07845|1|1e-138|495|mmu:56437|Ras-related associated with diabetes GO:0044464;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0016049//cell growth gi|114145497|ref|NP_062636.2|/1.0568e-137/GTP-binding protein RAD [Mus musculus] 81904 828 4.286666667 2.943333333 -0.5424053 Down 0.494142314 Cacng7 "calcium channel, voltage-dependent, gamma subunit 7" K04872|1|6e-147|521|pale:102888718|voltage-dependent calcium channel gamma-7 GO:0034704//calcium channel complex;GO:0008328//ionotropic glutamate receptor complex GO:0005262//calcium channel activity GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0010469//regulation of receptor activity gi|927142954|ref|XP_013854203.1|/5.04863e-146/PREDICTED: voltage-dependent calcium channel gamma-7 subunit isoform X1 [Sus scrofa] 102466236 57 0.44 0.01 -5.459431619 Down 0.493869645 Mir7658 microRNA 7658 - - - - - 11812 432 0.01 0.443333333 5.470319935 Up 0.493869645 Apoc1 apolipoprotein C-I K04524|1|4e-12|72.8|shr:100920637|apolipoprotein E GO:0034385;GO:0043231//intracellular membrane-bounded organelle;GO:0034385;GO:0043231//intracellular membrane-bounded organelle GO:0055102//lipase inhibitor activity;GO:0008289//lipid binding;GO:0055102//lipase inhibitor activity;GO:0008289//lipid binding GO:0051004;GO:0016125//sterol metabolic process;GO:0010899//regulation of phosphatidylcholine catabolic process;GO:0006898//receptor-mediated endocytosis;GO:0006639//acylglycerol metabolic process;GO:0015914//phospholipid transport;GO:0010915;GO:0009895;GO:0006633//fatty acid biosynthetic process;GO:0030301//cholesterol transport;GO:0071830;GO:0034368;GO:0019538//protein metabolic process;GO:0051004;GO:0016125//sterol metabolic process;GO:0010899//regulation of phosphatidylcholine catabolic process;GO:0006898//receptor-mediated endocytosis;GO:0006639//acylglycerol metabolic process;GO:0015914//phospholipid transport;GO:0010915;GO:0009895;GO:0006633//fatty acid biosynthetic process;GO:0030301//cholesterol transport;GO:0071830;GO:0034368;GO:0019538//protein metabolic process gi|6680704|ref|NP_031495.1|/2.87009e-41/apolipoprotein C-I precursor [Mus musculus] 102465196 131 0.01 0.436666667 5.448460501 Up 0.493643988 Mir6376 microRNA 6376 - - - - - 20615 1916 41.45666667 49.78333333 0.264058711 Up 0.493578171 Snapin SNAP-associated protein K20002|1|3e-59|232|cge:100752727|SNARE-associated protein Snapin GO:0031981//nuclear lumen;GO:0008021//synaptic vesicle;GO:0042995//cell projection;GO:0031082;GO:0012505//endomembrane system GO:0005515//protein binding GO:0048753//pigment granule organization;GO:0006906//vesicle fusion;GO:0015031//protein transport;GO:0006887//exocytosis;GO:0048489//synaptic vesicle transport;GO:0030030//cell projection organization;GO:0008088//axo-dendritic transport;GO:0001505//regulation of neurotransmitter levels "gi|148683189|gb|EDL15136.1|/4.38432e-59/SNAP-associated protein, isoform CRA_a, partial [Mus musculus]" 624341 1642 14.20666667 17.57 0.306546099 Up 0.493502952 Olfr856-ps1 "olfactory receptor 856, pseudogene 1" K04257|1|1e-69|266|rno:405169|olfactory receptor - - - gi|589948938|ref|XP_006987128.1|/8.44887e-69/PREDICTED: olfactory receptor 7D4-like [Peromyscus maniculatus bairdii] 56690 2116 75.55666667 90.04666667 0.253113816 Up 0.49349355 Mlycd malonyl-CoA decarboxylase K01578|1|0.0|923|mmu:56690|malonyl-CoA decarboxylase [EC:4.1.1.9] GO:0042579//microbody GO:0005515//protein binding;GO:0016831//carboxy-lyase activity GO:0006635//fatty acid beta-oxidation;GO:0006084//acetyl-CoA metabolic process;GO:0006006//glucose metabolic process;GO:0015938//coenzyme A catabolic process;GO:0019217//regulation of fatty acid metabolic process "gi|56797739|ref|NP_064350.2|/0/malonyl-CoA decarboxylase, mitochondrial [Mus musculus]" 26362 4978.09 36.75333333 30.57 -0.265758548 Down 0.49349355 Axl AXL receptor tyrosine kinase K05115|1|0.0|1740|mmu:26362|AXL receptor tyrosine kinase [EC:2.7.10.1] GO:0031224//intrinsic component of membrane;GO:0044464;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0044421 GO:0004713//protein tyrosine kinase activity;GO:0017022//myosin binding;GO:0005543//phospholipid binding;GO:0032550;GO:0046983//protein dimerization activity;GO:0004713//protein tyrosine kinase activity;GO:0017022//myosin binding;GO:0005543//phospholipid binding;GO:0032550;GO:0046983//protein dimerization activity;GO:0004713//protein tyrosine kinase activity;GO:0017022//myosin binding;GO:0005543//phospholipid binding;GO:0032550;GO:0046983//protein dimerization activity GO:0001779//natural killer cell differentiation;GO:0021700//developmental maturation;GO:0034614//cellular response to reactive oxygen species;GO:0009888//tissue development;GO:0048872//homeostasis of number of cells;GO:0048232//male gamete generation;GO:0097048;GO:0006952//defense response;GO:0006796//phosphate-containing compound metabolic process;GO:0046903//secretion;GO:0002695//negative regulation of leukocyte activation;GO:0016477//cell migration;GO:0000904//cell morphogenesis involved in differentiation;GO:0048771//tissue remodeling;GO:0030540//female genitalia development;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0006464//cellular protein modification process;GO:0043066//negative regulation of apoptotic process;GO:0001818//negative regulation of cytokine production;GO:0035455//response to interferon-alpha;GO:0032496//response to lipopolysaccharide;GO:0009887//organ morphogenesis;GO:0006909//phagocytosis;GO:0001779//natural killer cell differentiation;GO:0021700//developmental maturation;GO:0034614//cellular response to reactive oxygen species;GO:0009888//tissue development;GO:0048872//homeostasis of number of cells;GO:0048232//male gamete generation;GO:0097048;GO:0006952//defense response;GO:0006796//phosphate-containing compound metabolic process;GO:0046903//secretion;GO:0002695//negative regulation of leukocyte activation;GO:0016477//cell migration;GO:0000904//cell morphogenesis involved in differentiation;GO:0048771//tissue remodeling;GO:0030540//female genitalia development;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0006464//cellular protein modification process;GO:0043066//negative regulation of apoptotic process;GO:0001818//negative regulation of cytokine production;GO:0035455//response to interferon-alpha;GO:0032496//response to lipopolysaccharide;GO:0009887//organ morphogenesis;GO:0006909//phagocytosis;GO:0001779//natural killer cell differentiation;GO:0021700//developmental maturation;GO:0034614//cellular response to reactive oxygen species;GO:0009888//tissue development;GO:0048872//homeostasis of number of cells;GO:0048232//male gamete generation;GO:0097048;GO:0006952//defense response;GO:0006796//phosphate-containing compound metabolic process;GO:0046903//secretion;GO:0002695//negative regulation of leukocyte activation;GO:0016477//cell migration;GO:0000904//cell morphogenesis involved in differentiation;GO:0048771//tissue remodeling;GO:0030540//female genitalia development;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0006464//cellular protein modification process;GO:0043066//negative regulation of apoptotic process;GO:0001818//negative regulation of cytokine production;GO:0035455//response to interferon-alpha;GO:0032496//response to lipopolysaccharide;GO:0009887//organ morphogenesis;GO:0006909//phagocytosis gi|300794860|ref|NP_001177903.1|/0/tyrosine-protein kinase receptor UFO isoform 2 precursor [Mus musculus] 77521 7543 18.88333333 23.1 0.290779396 Up 0.493173869 Mtus2 microtubule associated tumor suppressor candidate 2 K14562|1|6e-07|60.8|cfr:102511752|Treacher Collins syndrome protein;K17498|2|7e-06|57.4|bacu:103016618|transcription factor SPN1 GO:0015630//microtubule cytoskeleton GO:0015631//tubulin binding;GO:0042802//identical protein binding - gi|75832043|ref|NP_084196.4|/0/microtubule-associated tumor suppressor candidate 2 homolog [Mus musculus] 67268 1779 448.83 380.3166667 -0.238967946 Down 0.493155064 Myl12a "myosin, light chain 12A, regulatory, non-sarcomeric" K12757|1|2e-87|325|rno:501203|myosin regulatory light chain 12 GO:0016459//myosin complex;GO:0031674//I band;GO:0032432//actin filament bundle GO:0046872//metal ion binding;GO:0005102//receptor binding GO:0022604//regulation of cell morphogenesis;GO:0006612//protein targeting to membrane "gi|71037403|ref|NP_080340.2|/1.70041e-86/myosin light chain, regulatory B-like [Mus musculus]" 170721 4309 4.293333333 2.96 -0.536501012 Down 0.492938809 Papln "papilin, proteoglycan-like sulfated glycoprotein" K08621|1|2e-101|373|gga:427160|a disintegrin and metalloproteinase with thrombospondin motifs 6 [EC:3.4.24.-] GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0004866//endopeptidase inhibitor activity;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0004866//endopeptidase inhibitor activity" GO:0051346//negative regulation of hydrolase activity;GO:0051346//negative regulation of hydrolase activity gi|158711721|ref|NP_570957.2|/0/papilin isoform 2 precursor [Mus musculus] 26394 1593 29.54333333 35.58 0.268233898 Up 0.49270375 Lypla2 lysophospholipase 2 K06130|1|3e-135|484|ssc:100621493|lysophospholipase II [EC:3.1.1.5] - GO:0003824//catalytic activity GO:0044238//primary metabolic process;GO:0032787//monocarboxylic acid metabolic process gi|676278513|gb|KFO32543.1|/7.67595e-144/Acyl-protein thioesterase 2 [Fukomys damarensis] 110959 1927 29.21666667 35.25333333 0.270968086 Up 0.49270375 Nudt19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 "K13355|1|0.0|649|mmu:110959|nucleoside diphosphate-linked moiety X motif 19, mitochondrial [EC:3.6.1.-]" - - - - 66943 1942.5 13.74 17.06333333 0.312517501 Up 0.49266614 Pqlc1 PQ loop repeat containing 1 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|257096053|ref|NP_001157892.1|/1.16048e-136/PQ-loop repeat-containing protein 1 isoform b [Mus musculus] 68539 1943 73.43666667 87.03333333 0.245067476 Up 0.492628531 Tmem109 transmembrane protein 109 - GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network;GO:0031090//organelle membrane;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum - GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage "gi|148709443|gb|EDL41389.1|/5.91301e-80/transmembrane protein 109, isoform CRA_c [Mus musculus]" 751526 110 0.98 1.886666667 0.944985898 Up 0.492609726 Mir719 microRNA 719 K14307|1|3e-13|75.5|tup:102495656|nucleoporin p58/p45 GO:0005635//nuclear envelope GO:0005488//binding GO:0050658//RNA transport;GO:0045184//establishment of protein localization;GO:0051169//nuclear transport "gi|148704172|gb|EDL36119.1|/3.08811e-12/nucleoporin like 1, isoform CRA_a [Mus musculus]" 71755 2738 9.46 7.306666667 -0.372626791 Down 0.492543909 Dhdh dihydrodiol dehydrogenase (dimeric) K00078|1|2e-180|635|mmu:71755|dihydrodiol dehydrogenase / D-xylose 1-dehydrogenase (NADP) [EC:1.3.1.20 1.1.1.179] - "GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0044710;GO:0019323//pentose catabolic process "gi|27229131|ref|NP_082179.1|/1.29767e-179/trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [Mus musculus]" 56448 2782 10.57333333 13.31666667 0.332802732 Up 0.492186619 Cyp2d22 "cytochrome P450, family 2, subfamily d, polypeptide 22" "K07414|1|0.0|1005|mmu:56448|cytochrome P450, family 2, subfamily D [EC:1.14.14.1];K17712|5|0.0|757|mcc:678691|cytochrome P450, family 2, subfamily D, polypeptide 6 [EC:1.14.14.1]" GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0008395//steroid hydroxylase activity;GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0008395//steroid hydroxylase activity" GO:0044703;GO:0055114//oxidation-reduction process;GO:0090348;GO:0044092//negative regulation of molecular function;GO:0009698//phenylpropanoid metabolic process;GO:0042221//response to chemical;GO:0006721//terpenoid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0042417//dopamine metabolic process;GO:0017144//drug metabolic process;GO:0009820//alkaloid metabolic process;GO:0044703;GO:0055114//oxidation-reduction process;GO:0090348;GO:0044092//negative regulation of molecular function;GO:0009698//phenylpropanoid metabolic process;GO:0042221//response to chemical;GO:0006721//terpenoid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0042417//dopamine metabolic process;GO:0017144//drug metabolic process;GO:0009820//alkaloid metabolic process "gi|148672557|gb|EDL04504.1|/0/mCG20388, isoform CRA_a, partial [Mus musculus]" 434130 2058 2.356666667 3.563333333 0.596479733 Up 0.492092595 Ccdc8 coiled-coil domain containing 8 K17561|1|2e-164|582|mmu:434130|coiled-coil domain-containing protein 8 - - GO:0010921//regulation of phosphatase activity gi|201022271|ref|NP_001095005.1|/1.58426e-163/coiled-coil domain-containing protein 8 homolog [Mus musculus] 15361 1705.89 68.98 82.05333333 0.250383814 Up 0.492092595 Hmga1 high mobility group AT-hook 1 K09282|1|3e-16|89.7|mmu:15361|high mobility group AT-hook protein 1 GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0000792//heterochromatin;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0000792//heterochromatin;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0000792//heterochromatin;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0000792//heterochromatin;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0000792//heterochromatin;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0000792//heterochromatin;GO:0031981//nuclear lumen;GO:0000792//heterochromatin;GO:0031981//nuclear lumen;GO:0000792//heterochromatin;GO:0031981//nuclear lumen;GO:0000792//heterochromatin;GO:0031981//nuclear lumen;GO:0000792//heterochromatin;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0000792//heterochromatin;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0000792//heterochromatin;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0000792//heterochromatin;GO:0031981//nuclear lumen;GO:0000792//heterochromatin GO:0016835//carbon-oxygen lyase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0016835//carbon-oxygen lyase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0016835//carbon-oxygen lyase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0016835//carbon-oxygen lyase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0016835//carbon-oxygen lyase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0016835//carbon-oxygen lyase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0003677//DNA binding;GO:0016835//carbon-oxygen lyase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0003677//DNA binding;GO:0016835//carbon-oxygen lyase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0003677//DNA binding;GO:0016835//carbon-oxygen lyase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0003677//DNA binding;GO:0016835//carbon-oxygen lyase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0003677//DNA binding;GO:0016835//carbon-oxygen lyase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0016835//carbon-oxygen lyase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0016835//carbon-oxygen lyase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0003677//DNA binding;GO:0016835//carbon-oxygen lyase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0003677//DNA binding "GO:0090398//cellular senescence;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0034728//nucleosome organization;GO:0044764;GO:0006342//chromatin silencing;GO:0065003;GO:0048232//male gamete generation;GO:0048584;GO:0031507//heterochromatin assembly;GO:0006281//DNA repair;GO:0090398//cellular senescence;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0034728//nucleosome organization;GO:0044764;GO:0006342//chromatin silencing;GO:0065003;GO:0048232//male gamete generation;GO:0048584;GO:0031507//heterochromatin assembly;GO:0006281//DNA repair;GO:0090398//cellular senescence;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0034728//nucleosome organization;GO:0044764;GO:0006342//chromatin silencing;GO:0065003;GO:0048232//male gamete generation;GO:0048584;GO:0031507//heterochromatin assembly;GO:0006281//DNA repair;GO:0090398//cellular senescence;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0034728//nucleosome organization;GO:0044764;GO:0006342//chromatin silencing;GO:0065003;GO:0048232//male gamete generation;GO:0048584;GO:0031507//heterochromatin assembly;GO:0006281//DNA repair;GO:0090398//cellular senescence;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0034728//nucleosome organization;GO:0044764;GO:0006342//chromatin silencing;GO:0065003;GO:0048232//male gamete generation;GO:0048584;GO:0031507//heterochromatin assembly;GO:0006281//DNA repair;GO:0090398//cellular senescence;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0044764;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048584;GO:0031507//heterochromatin assembly;GO:0022414//reproductive process;GO:0043933;GO:0006281//DNA repair;GO:0090398//cellular senescence;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0044764;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048584;GO:0031507//heterochromatin assembly;GO:0022414//reproductive process;GO:0043933;GO:0006281//DNA repair;GO:0090398//cellular senescence;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0044764;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048584;GO:0031507//heterochromatin assembly;GO:0022414//reproductive process;GO:0043933;GO:0006281//DNA repair;GO:0090398//cellular senescence;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0044764;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048584;GO:0031507//heterochromatin assembly;GO:0022414//reproductive process;GO:0043933;GO:0006281//DNA repair;GO:0090398//cellular senescence;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0044764;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048584;GO:0031507//heterochromatin assembly;GO:0022414//reproductive process;GO:0043933;GO:0006281//DNA repair;GO:0090398//cellular senescence;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0034728//nucleosome organization;GO:0044764;GO:0006342//chromatin silencing;GO:0065003;GO:0048232//male gamete generation;GO:0048584;GO:0031507//heterochromatin assembly;GO:0006281//DNA repair;GO:0090398//cellular senescence;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0034728//nucleosome organization;GO:0044764;GO:0006342//chromatin silencing;GO:0065003;GO:0048232//male gamete generation;GO:0048584;GO:0031507//heterochromatin assembly;GO:0006281//DNA repair;GO:0090398//cellular senescence;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0044764;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048232//male gamete generation;GO:0048584;GO:0031507//heterochromatin assembly;GO:0043933;GO:0006281//DNA repair;GO:0090398//cellular senescence;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0044764;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048232//male gamete generation;GO:0048584;GO:0031507//heterochromatin assembly;GO:0043933;GO:0006281//DNA repair" gi|625207681|ref|XP_007644976.1|/4.19722e-26/PREDICTED: high mobility group protein HMG-I/HMG-Y isoform X2 [Cricetulus griseus] 15894 2540 8.526666667 10.89666667 0.353833113 Up 0.491763511 Icam1 intercellular adhesion molecule 1 K06490|1|0.0|1016|mmu:15894|intercellular adhesion molecule 1 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0044421 GO:0005102//receptor binding GO:0002687//positive regulation of leukocyte migration;GO:0070555//response to interleukin-1;GO:0019229//regulation of vasoconstriction;GO:0002286//T cell activation involved in immune response;GO:0014075//response to amine;GO:0006809//nitric oxide biosynthetic process;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0016337//single organismal cell-cell adhesion;GO:0001678//cellular glucose homeostasis;GO:0031667//response to nutrient levels;GO:0009314//response to radiation;GO:0043279//response to alkaloid;GO:0019062//virion attachment to host cell;GO:0001666//response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0007568//aging;GO:0022406//membrane docking;GO:0002456//T cell mediated immunity;GO:0051702//interaction with symbiont;GO:0001101//response to acid chemical;GO:0010038//response to metal ion;GO:0022604//regulation of cell morphogenesis;GO:0030041//actin filament polymerization;GO:0006816//calcium ion transport;GO:0009725//response to hormone;GO:0097305//response to alcohol;GO:0034612//response to tumor necrosis factor;GO:0032496//response to lipopolysaccharide gi|21389311|ref|NP_034623.1|/0/intercellular adhesion molecule 1 precursor [Mus musculus] 213233 2080 3.953333333 5.476666667 0.47022847 Up 0.49167889 Tapbpl TAP binding protein-like K08058|1|1e-31|140|cmk:103191457|TAP binding protein (tapasin) - - - gi|255069728|ref|NP_663366.2|/0/tapasin-related protein precursor [Mus musculus] 14201 1685 6.34 8.296666667 0.388048984 Up 0.491650683 Fhl3 four and a half LIM domains 3 K12827|1|1e-138|495|gfr:102040976|splicing factor 3A subunit 3 GO:0043231//intracellular membrane-bounded organelle;GO:0031674//I band GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding GO:0007010//cytoskeleton organization gi|568928422|ref|XP_006502829.1|/9.35938e-180/PREDICTED: four and a half LIM domains protein 3 isoform X2 [Mus musculus] 11603 7379 14.59333333 11.66333333 -0.32332929 Down 0.491613073 Agrn agrin K06254|1|0.0|3968|mmu:11603|agrin - - - gi|344217723|ref|NP_067617.3|/0/agrin precursor [Mus musculus] 68799 2633 6.93 5.183333333 -0.418975178 Down 0.491594268 Rgmb repulsive guidance molecule family member B K06847|1|0.0|781|mmu:68799|RGM domain family GO:0031225//anchored component of membrane GO:0005515//protein binding "GO:0022610;GO:0006351//transcription, DNA-templated;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway" gi|569001499|ref|XP_006524926.1|/0/PREDICTED: RGM domain family member B isoform X2 [Mus musculus] 269016 4784 9.406666667 7.273333333 -0.371066886 Down 0.491594268 Sh3rf2 SH3 domain containing ring finger 2 K12171|1|0.0|1355|mmu:269016|E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27] - GO:0046914//transition metal ion binding;GO:0019903//protein phosphatase binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0019903//protein phosphatase binding;GO:0003824//catalytic activity GO:0010921//regulation of phosphatase activity;GO:0032446//protein modification by small protein conjugation;GO:0044092//negative regulation of molecular function;GO:0010921//regulation of phosphatase activity;GO:0032446//protein modification by small protein conjugation;GO:0044092//negative regulation of molecular function "gi|148678098|gb|EDL10045.1|/0/SH3 domain containing ring finger 2, isoform CRA_b, partial [Mus musculus]" 268373 736 258.47 304.6066667 0.236950677 Up 0.491528452 Ppia peptidylprolyl isomerase A K03767|1|3e-94|279|cge:103159182|peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0016859//cis-trans isomerase activity GO:0019079//viral genome replication;GO:0006996//organelle organization;GO:0009306//protein secretion;GO:0030154//cell differentiation gi|913486493|ref|XP_005343481.2|/2.69068e-94/PREDICTED: peptidyl-prolyl cis-trans isomerase A-like [Microtus ochrogaster] 54615 451 0.923333333 1.816666667 0.976370254 Up 0.491378013 Npff neuropeptide FF-amide peptide precursor K05247|1|1e-58|226|mmu:54615|neuropeptide FF-amide peptide - - - - 18826 3748 4.603333333 6.24 0.438867115 Up 0.491340404 Lcp1 lymphocyte cytosolic protein 1 K17276|1|0.0|1273|ptg:102960827|plastin-2 GO:0044459;GO:0031252//cell leading edge;GO:0044444//cytoplasmic part;GO:0015629//actin cytoskeleton GO:0046872//metal ion binding;GO:0003779//actin binding GO:0007015//actin filament organization;GO:0009887//organ morphogenesis;GO:0002285;GO:0006886//intracellular protein transport;GO:0006950//response to stress gi|591318376|ref|XP_007085449.1|/0/PREDICTED: plastin-2 isoform X1 [Panthera tigris altaica] 320292 2993 5.55 7.376666667 0.410481274 Up 0.491208771 Rasgef1b "RasGEF domain family, member 1B" K17636|1|1e-23|115|xma:102232099|ral guanine nucleotide dissociation stimulator-like 2;K06277|4|2e-20|103|bfo:BRAFLDRAFT_124752|Rap guanine nucleotide exchange factor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0007264//small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction gi|31044455|ref|NP_851835.1|/0/ras-GEF domain-containing family member 1B isoform 2 [Mus musculus] 20701 1434 1.656666667 0.816666667 -1.020464103 Down 0.491189966 Serpina1b "serine (or cysteine) preptidase inhibitor, clade A, member 1B" K03984|1|0.0|786|mmu:20701|alpha-1-antitrypsin - - - gi|76881807|ref|NP_033270.3|/0/alpha-1-antitrypsin 1-2 precursor [Mus musculus] 12495 4221 8.73 6.7 -0.381820558 Down 0.491180563 Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 K01510|1|0.0|1030|mmu:12495|apyrase [EC:3.6.1.5] GO:0031224//intrinsic component of membrane;GO:0005604//basement membrane;GO:0031224//intrinsic component of membrane;GO:0005604//basement membrane GO:0032550;GO:0016462//pyrophosphatase activity;GO:0032550;GO:0016462//pyrophosphatase activity GO:0009154//purine ribonucleotide catabolic process;GO:0001775//cell activation;GO:0009137;GO:0007166//cell surface receptor signaling pathway;GO:0009154//purine ribonucleotide catabolic process;GO:0001775//cell activation;GO:0009137;GO:0007166//cell surface receptor signaling pathway gi|754170702|ref|NP_001291650.1|/0/ectonucleoside triphosphate diphosphohydrolase 1 isoform 1 [Mus musculus] 229534 4481 45.92666667 38.40666667 -0.25797532 Down 0.49085148 Pbxip1 pre B cell leukemia transcription factor interacting protein 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton - "GO:0006351//transcription, DNA-templated" gi|22122651|ref|NP_666243.1|/0/pre-B-cell leukemia transcription factor-interacting protein 1 [Mus musculus] 69168 729 13.36 16.59333333 0.312683722 Up 0.490842078 Bola1 bolA-like 1 (E. coli) K05527|1|9e-61|235|mmu:69168|BolA protein GO:0043231//intracellular membrane-bounded organelle - - gi|58037151|ref|NP_081251.1|/7.25618e-60/bolA-like protein 1 [Mus musculus] 20320 2071.46 38.41333333 45.90666667 0.25709652 Up 0.490738651 Nptn neuroplastin K06535|1|6e-49|198|acs:103281913|basigin GO:0031224//intrinsic component of membrane;GO:0097060//synaptic membrane;GO:0031224//intrinsic component of membrane;GO:0097060//synaptic membrane GO:0005104//fibroblast growth factor receptor binding;GO:0005104//fibroblast growth factor receptor binding GO:0016337//single organismal cell-cell adhesion;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010975//regulation of neuron projection development;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0016337//single organismal cell-cell adhesion;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010975//regulation of neuron projection development;GO:0051480//regulation of cytosolic calcium ion concentration gi|153945724|ref|NP_033171.2|/3.59371e-139/neuroplastin isoform 1 precursor [Mus musculus] 58998 2679.92 2.083333333 1.14 -0.869859865 Down 0.490672835 Pvrl3 nectin cell adhesion molecule 3 K06592|1|0.0|755|rno:288124|poliovirus receptor-related protein 3 GO:0005911//cell-cell junction;GO:0031224//intrinsic component of membrane;GO:0005911//cell-cell junction;GO:0031224//intrinsic component of membrane;GO:0005911//cell-cell junction;GO:0031224//intrinsic component of membrane GO:0042802//identical protein binding;GO:0042802//identical protein binding;GO:0042802//identical protein binding GO:0002088//lens development in camera-type eye;GO:0016337//single organismal cell-cell adhesion;GO:0009653//anatomical structure morphogenesis;GO:0019953//sexual reproduction;GO:0002088//lens development in camera-type eye;GO:0045216//cell-cell junction organization;GO:0016337//single organismal cell-cell adhesion;GO:0009653//anatomical structure morphogenesis;GO:0022607//cellular component assembly;GO:0019953//sexual reproduction;GO:0002088//lens development in camera-type eye;GO:0016337//single organismal cell-cell adhesion;GO:0009653//anatomical structure morphogenesis;GO:0019953//sexual reproduction gi|12957494|ref|NP_067471.1|/0/nectin-3 isoform beta [Mus musculus] 67246 6122.16 2.126666667 3.286666667 0.628031223 Up 0.490663432 2810474O19Rik RIKEN cDNA 2810474O19 gene - - - - - 229599 1395 10.60666667 13.29333333 0.325731574 Up 0.49065403 Ciart circadian associated repressor of transcription - - - - gi|85701804|ref|NP_001028474.1|/2.74789e-179/circadian-associated transcriptional repressor [Mus musculus] 20618 757 9.346666667 7.24 -0.368462246 Down 0.490578811 Sncg "synuclein, gamma" K04528|1|2e-21|105|pbi:103053330|alpha-synuclein GO:0030424//axon;GO:0044297//cell body;GO:0044424 GO:0015631//tubulin binding GO:0007626//locomotory behavior;GO:0007269//neurotransmitter secretion;GO:0010646//regulation of cell communication;GO:0016043//cellular component organization "gi|148692930|gb|EDL24877.1|/8.75744e-43/synuclein, gamma, partial [Mus musculus]" 233806 1427 15.22 18.78333333 0.303484751 Up 0.490560006 Tmem159 transmembrane protein 159 - GO:0016020//membrane - - gi|21704178|ref|NP_663561.1|/6.53707e-59/promethin [Mus musculus] 68636 1408 32.97666667 27.27333333 -0.27395454 Down 0.490268532 Fahd1 fumarylacetoacetate hydrolase domain containing 1 K01557|1|6e-129|463|mmu:68636|acylpyruvate hydrolase [EC:3.7.1.5] - - - - 434437 1325 1.973333333 3.1 0.65163354 Up 0.490089887 Amt aminomethyltransferase K00605|1|0.0|804|mmu:434437|aminomethyltransferase [EC:2.1.2.10] - - - "gi|62000670|ref|NP_001013836.1|/0/aminomethyltransferase, mitochondrial precursor [Mus musculus]" 100526504 65 10.22 12.88666667 0.334483941 Up 0.490052277 Mir3100 microRNA 3100 - - - - - 68655 5846 5.363333333 3.863333333 -0.47328376 Down 0.489920644 Fndc1 fibronectin type III domain containing 1 K06766|1|6e-36|156|phu:Phum_PHUM206390|neogenin GO:0030054//cell junction;GO:0005740//mitochondrial envelope;GO:0016020//membrane - GO:0001666//response to hypoxia;GO:0010659//cardiac muscle cell apoptotic process;GO:0015031//protein transport gi|568998294|ref|XP_006523414.1|/0/PREDICTED: fibronectin type III domain-containing protein 1 isoform X3 [Mus musculus] 73024 1072 35.89 43.11 0.264440639 Up 0.489647975 Emc7 ER membrane protein complex subunit 7 K02941|1|3e-06|55.5|tup:102493835|large subunit ribosomal protein LP0 GO:0030176//integral component of endoplasmic reticulum membrane GO:0005488//binding - gi|19526956|ref|NP_598510.1|/2.10779e-90/ER membrane protein complex subunit 7 precursor [Mus musculus] 232089 2251 17.42333333 21.37 0.294566249 Up 0.489506939 Elmod3 ELMO/CED-12 domain containing 3 K04139|1|2e-83|313|gga:426044|adrenergic receptor alpha-2B;K00629|2|8e-66|254|tgu:101233683|glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15] GO:0043232;GO:0043232 - GO:0006897//endocytosis;GO:0006897//endocytosis gi|21450313|ref|NP_659166.1|/0/ELMO domain-containing protein 3 [Mus musculus] 21678 2616 9.196666667 11.64333333 0.340321186 Up 0.489497537 Tead3 TEA domain family member 3 K09448|1|0.0|687|tup:102485832|transcriptional enhancer factor GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity GO:0035556//intracellular signal transduction;GO:0006366//transcription from RNA polymerase II promoter gi|196049391|ref|NP_001091696.2|/0/transcriptional enhancer factor TEF-5 isoform 1 [Mus musculus] 23872 3560 42.99333333 35.83 -0.262944925 Down 0.489347098 Ets2 "E26 avian leukemia oncogene 2, 3' domain" K02678|1|0.0|942|mmu:23872|C-ets GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0035258//steroid hormone receptor binding;GO:0000976//transcription regulatory region sequence-specific DNA binding GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter gi|74191433|dbj|BAE30296.1|/0/unnamed protein product [Mus musculus] 57344 1752 26.77333333 32.34666667 0.272820281 Up 0.489328294 As3mt arsenic (+3 oxidation state) methyltransferase K07755|1|0.0|735|mmu:57344|arsenite methyltransferase [EC:2.1.1.137] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0008757//S-adenosylmethionine-dependent methyltransferase activity GO:0008213;GO:0019748//secondary metabolic process;GO:0006805//xenobiotic metabolic process gi|119392105|ref|NP_065602.2|/0/arsenite methyltransferase [Mus musculus] 21340 2007.18 6.463333333 4.803333333 -0.428242468 Down 0.489309489 Taf1b "TATA-box binding protein associated factor, RNA polymerase I, B" K15213|1|0.0|868|mmu:21340|TATA box-binding protein-associated factor RNA polymerase I subunit B GO:0000120//RNA polymerase I transcription factor complex;GO:0000120//RNA polymerase I transcription factor complex "GO:0043169//cation binding;GO:0001169//transcription factor activity, RNA polymerase I CORE element sequence-specific binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0043169//cation binding;GO:0001169//transcription factor activity, RNA polymerase I CORE element sequence-specific binding;GO:0001046//core promoter sequence-specific DNA binding" GO:0001180//transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript;GO:0001180//transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript gi|256773270|ref|NP_065639.2|/0/TATA box-binding protein-associated factor RNA polymerase I subunit B [Mus musculus] 78849 2349 3.813333333 2.57 -0.569284287 Down 0.489027417 B430010I23Rik RIKEN cDNA B430010I23 gene - - - - - 57373 973 8.67 6.683333333 -0.375464163 Down 0.489027417 Akip1 A kinase (PRKA) interacting protein 1 - GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle - GO:0000904//cell morphogenesis involved in differentiation gi|10181162|ref|NP_065641.1|/2.17691e-120/A-kinase-interacting protein 1 [Mus musculus] 99480 2427 16.32 13.17333333 -0.309020611 Down 0.488933394 Dnttip2 "deoxynucleotidyltransferase, terminal, interacting protein 2" K03942|1|4e-26|122|tsp:Tsp_02641|NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3] GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated" gi|24418931|ref|NP_722501.1|/0/deoxynucleotidyltransferase terminal-interacting protein 2 [Mus musculus] 20922 693 21.64333333 26.19333333 0.275276958 Up 0.488820565 Supt4a suppressor of Ty 4A K15171|1|5e-63|242|pale:102883617|transcription elongation factor SPT4 GO:0008023//transcription elongation factor complex "GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0008135//translation factor activity, RNA binding" "GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006412//translation;GO:0044764;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016568//chromatin modification" gi|823401762|ref|XP_004397693.2|/1.26676e-63/PREDICTED: transcription elongation factor SPT4 [Odobenus rosmarus divergens] 59021 2057 56.78666667 67.65333333 0.25260879 Up 0.488679529 Rab2a "RAB2A, member RAS oncogene family" K07877|1|3e-103|378|lcm:102367697|Ras-related protein Rab-2A GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0044297//cell body;GO:0048770;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0007265//Ras protein signal transduction;GO:0016482//cytosolic transport;GO:0015031//protein transport;GO:0009154//purine ribonucleotide catabolic process gi|1588651|prf||2209256A/2.65531e-102/rab2 gene [Gallus gallus] 67768 1791 13.11 16.24 0.308883947 Up 0.488557298 N6amt1 N-6 adenine-specific DNA methyltransferase 1 (putative) K19589|1|1e-64|249|mmu:67768|release factor glutamine methyltransferase [EC:2.1.1.297] GO:0032991//macromolecular complex;GO:0032991//macromolecular complex GO:0008168//methyltransferase activity;GO:0008168//methyltransferase activity GO:0016049//cell growth;GO:0008152//metabolic process;GO:0016049//cell growth;GO:0008152//metabolic process gi|39540506|ref|NP_080642.1|/4.18725e-109/hemK methyltransferase family member 2 isoform 1 [Mus musculus] 11819 4212.73 6.473333333 4.82 -0.425475648 Down 0.488510286 Nr2f2 "nuclear receptor subfamily 2, group F, member 2" K08548|1|2e-159|566|ecb:100146166|COUP transcription factor 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0003712//transcription cofactor activity;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0005501//retinoid binding;GO:0046914//transition metal ion binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0005501//retinoid binding;GO:0046914//transition metal ion binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding" GO:0001935//endothelial cell proliferation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007420//brain development;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0014706//striated muscle tissue development;GO:0060838//lymphatic endothelial cell fate commitment;GO:0019953//sexual reproduction;GO:0010594//regulation of endothelial cell migration;GO:0043627//response to estrogen;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0048736;GO:0003002//regionalization;GO:0001568//blood vessel development;GO:0001935//endothelial cell proliferation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007420//brain development;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0014706//striated muscle tissue development;GO:0060838//lymphatic endothelial cell fate commitment;GO:0019953//sexual reproduction;GO:0010594//regulation of endothelial cell migration;GO:0043627//response to estrogen;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0048736;GO:0003002//regionalization;GO:0001568//blood vessel development gi|73611910|ref|NP_899084.2|/2.03005e-158/COUP transcription factor 2 isoform 2 [Mus musculus] 77057 2983 6.4 4.746666667 -0.431157165 Down 0.488510286 Ston1 stonin 1 K20067|1|0.0|1416|mmu:77057|stonin-1/2 GO:0030119//AP-type membrane coat adaptor complex - GO:0016192//vesicle-mediated transport;GO:0015031//protein transport gi|159032010|ref|NP_084134.2|/0/stonin-1 [Mus musculus] 77794 3242 11.66666667 9.243333333 -0.335907306 Down 0.488453872 Adamtsl2 ADAMTS-like 2 K08626|1|2e-54|217|sko:100377708|a disintegrin and metalloproteinase with thrombospondin motifs 12 [EC:3.4.24.-] GO:0031012//extracellular matrix GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0007179//transforming growth factor beta receptor signaling pathway "gi|148676410|gb|EDL08357.1|/0/ADAMTS-like 2, isoform CRA_b, partial [Mus musculus]" 12826 6636 184.5166667 156.51 -0.237496296 Down 0.488425665 Col4a1 "collagen, type IV, alpha 1" "K06237|1|0.0|1140|mmu:12826|collagen, type IV, alpha" - - - - 12452 2510 7.603333333 9.766666667 0.361234218 Up 0.488350446 Ccng2 cyclin G2 K10146|1|2e-167|592|mmu:12452|cyclin G2 GO:0044424 - GO:0000087//mitotic M phase gi|161621247|ref|NP_031661.3|/1.94218e-166/cyclin-G2 [Mus musculus] 66279 1098.99 9.966666667 12.56666667 0.334419039 Up 0.487899131 Tmem218 transmembrane protein 218 - GO:0016020//membrane;GO:0016020//membrane - - gi|854291733|ref|NP_001297025.1|/5.09126e-24/transmembrane protein 218 isoform 1 [Mus musculus] 14605 1997.03 55.48666667 66.01666667 0.250689159 Up 0.487880326 Tsc22d3 "TSC22 domain family, member 3" - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043425//bHLH transcription factor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0043425//bHLH transcription factor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0043425//bHLH transcription factor binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0046903//secretion;GO:0006915//apoptotic process;GO:0007519//skeletal muscle tissue development;GO:0006950//response to stress;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0007519//skeletal muscle tissue development;GO:0006351//transcription, DNA-templated;GO:0006950//response to stress;GO:0046903//secretion;GO:0006915//apoptotic process;GO:0007519//skeletal muscle tissue development;GO:0006950//response to stress;GO:0006366//transcription from RNA polymerase II promoter" gi|210148097|gb|ACJ09091.1|/2.14718e-86/long glucocorticoid-induced leucine zipper protein [Mus musculus] 15000 786 0.993333333 0.326666667 -1.604458676 Down 0.487541841 H2-DMb2 "histocompatibility 2, class II, locus Mb2" "K06752|1|1e-149|530|mmu:15000|major histocompatibility complex, class II" GO:0005770//late endosome;GO:0005764//lysosome;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0042611 GO:0005488//binding GO:0002478;GO:0051084//'de novo' posttranslational protein folding "gi|6754124|ref|NP_034518.1|/9.85584e-149/histocompatibility 2, class II, locus Mb2 precursor [Mus musculus]" 67242 1086 0.886666667 1.753333333 0.983636554 Up 0.487541841 Gemin6 gem (nuclear organelle) associated protein 6 K13134|1|2e-92|341|mmu:67242|gem associated protein 6 GO:0016604//nuclear body;GO:0044444//cytoplasmic part;GO:0030529//intracellular ribonucleoprotein complex GO:0005488//binding "GO:0000398//mRNA splicing, via spliceosome" gi|21313050|ref|NP_080329.1|/1.95096e-91/gem-associated protein 6 [Mus musculus] 56031 1168 11.18666667 13.95333333 0.318829596 Up 0.487513633 Ppie peptidylprolyl isomerase E (cyclophilin E) K09564|1|5e-161|569|mmu:56031|peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8] GO:0005681//spliceosomal complex GO:0008144//drug binding;GO:0003676//nucleic acid binding;GO:0016859//cis-trans isomerase activity;GO:0036094//small molecule binding "GO:0019079//viral genome replication;GO:0018208//peptidyl-proline modification;GO:0000377;GO:0006351//transcription, DNA-templated" gi|14196340|ref|NP_062362.1|/3.76289e-160/peptidyl-prolyl cis-trans isomerase E [Mus musculus] 93891 3418 0.523333333 1.263333333 1.271433289 Up 0.487165745 Pcdhb20 protocadherin beta 20 K16494|1|0.0|1441|mmu:93891|protocadherin beta GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion "gi|148678204|gb|EDL10151.1|/0/mCG141284, partial [Mus musculus]" 69320 1111 11.43 9.053333333 -0.336304425 Down 0.486855467 1700007J10Rik RIKEN cDNA 1700007J10 gene - - - - - 66864 4539 7.176666667 5.413333333 -0.406796687 Down 0.486582797 Clec14a "C-type lectin domain family 14, member a" K17528|1|0.0|840|mmu:66864|C-type lectin domain family 14 member A - - - - 66832 1960 33.63 40.17333333 0.256489393 Up 0.486432359 Rsph3a radial spoke 3A homolog (Chlamydomonas) - - - - gi|165377232|ref|NP_080065.4|/0/radial spoke head protein 3 homolog A [Mus musculus] 108153 5433.98 6.563333333 4.89 -0.42459424 Down 0.486404152 Adamts7 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7" K08622|1|0.0|3318|mmu:108153|a disintegrin and metalloproteinase with thrombospondin motifs 7 [EC:3.4.24.-] GO:0044464;GO:0031012//extracellular matrix GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|902763339|ref|NP_001298044.1|/0/A disintegrin and metalloproteinase with thrombospondin motifs 7 isoform 2 precursor [Mus musculus] 547150 4659 17.98666667 14.65333333 -0.295698962 Down 0.486206702 6820431F20Rik cadherin 11 pseudogene "K06803|1|3e-96|193|mmu:12552|cadherin 11, type 2, OB-cadherin" - - - - 69585 2021 119.0933333 140.6333333 0.239845931 Up 0.486065666 Hfe2 hemochromatosis type 2 (juvenile) K06847|1|0.0|656|mmu:69585|RGM domain family - - - - 269295 1263 4.143333333 5.673333333 0.453404741 Up 0.486009252 Rtn4rl2 reticulon 4 receptor-like 2 K16661|1|0.0|761|mmu:269295|reticulon-4 receptor-like 2 GO:0009986//cell surface;GO:0031225//anchored component of membrane - GO:0007409//axonogenesis;GO:0007165//signal transduction gi|40363807|ref|NP_954693.1|/0/reticulon-4 receptor-like 2 precursor [Mus musculus] 105083 1588 12.86 15.89 0.305228482 Up 0.48592463 Pelo pelota homolog (Drosophila) K06965|1|0.0|734|mmu:105083|protein pelota GO:0043231//intracellular membrane-bounded organelle GO:0004518//nuclease activity;GO:0043169//cation binding GO:0006996//organelle organization gi|164698448|ref|NP_598819.2|/0/protein pelota homolog [Mus musculus] 73833 1285 9.753333333 12.28666667 0.333126301 Up 0.485802399 Fam98c "family with sequence similarity 98, member C" "K04703|1|2e-83|311|phd:102343228|sprouty-related, EVH1 domain-containing protein;K15434|2|3e-31|138|cmk:103175194|protein FAM98B" - - - gi|225637492|ref|NP_001139495.1|/1.49678e-144/protein FAM98C [Mus musculus] 52357 5042 10.37 8.136666667 -0.3499061 Down 0.485783595 Wwc2 "WW, C2 and coiled-coil domain containing 2" K16685|1|1e-116|424|cmk:103184146|protein KIBRA - - - gi|46575912|ref|NP_598552.2|/0/protein WWC2 [Mus musculus] 11433 1367 0.803333333 0.196666667 -2.030246287 Down 0.485736583 Acp5 "acid phosphatase 5, tartrate resistant" K14379|1|0.0|637|rno:100911394|tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2] GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0044421 GO:0016791//phosphatase activity;GO:0005506//iron ion binding;GO:0016791//phosphatase activity;GO:0005506//iron ion binding;GO:0016791//phosphatase activity;GO:0005506//iron ion binding GO:0009653//anatomical structure morphogenesis;GO:0007155//cell adhesion;GO:0032611//interleukin-1 beta production;GO:0002573//myeloid leukocyte differentiation;GO:0001818//negative regulation of cytokine production;GO:0042742//defense response to bacterium;GO:0006796//phosphate-containing compound metabolic process;GO:0006809//nitric oxide biosynthetic process;GO:0033273//response to vitamin;GO:0010038//response to metal ion;GO:0036314;GO:0006954//inflammatory response;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0002237//response to molecule of bacterial origin;GO:0016477//cell migration;GO:0001894//tissue homeostasis;GO:0009653//anatomical structure morphogenesis;GO:0007155//cell adhesion;GO:0032611//interleukin-1 beta production;GO:0002573//myeloid leukocyte differentiation;GO:0001818//negative regulation of cytokine production;GO:0042742//defense response to bacterium;GO:0006796//phosphate-containing compound metabolic process;GO:0006809//nitric oxide biosynthetic process;GO:0033273//response to vitamin;GO:0010038//response to metal ion;GO:0036314;GO:0006954//inflammatory response;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0002237//response to molecule of bacterial origin;GO:0016477//cell migration;GO:0001894//tissue homeostasis;GO:0009653//anatomical structure morphogenesis;GO:0007155//cell adhesion;GO:0032611//interleukin-1 beta production;GO:0002573//myeloid leukocyte differentiation;GO:0001818//negative regulation of cytokine production;GO:0042742//defense response to bacterium;GO:0006796//phosphate-containing compound metabolic process;GO:0006809//nitric oxide biosynthetic process;GO:0033273//response to vitamin;GO:0010038//response to metal ion;GO:0036314;GO:0006954//inflammatory response;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0002237//response to molecule of bacterial origin;GO:0016477//cell migration;GO:0001894//tissue homeostasis gi|6680624|ref|NP_031414.1|/1.9507e-180/tartrate-resistant acid phosphatase type 5 precursor [Mus musculus] 73106 2693 3.566666667 2.383333333 -0.58159565 Down 0.48572718 Prss57 "protease, serine 57" K01334|1|8e-44|181|ssc:396877|component factor D [EC:3.4.21.46];K08649|5|5e-42|175|asn:102385169|granzyme M [EC:3.4.21.-] - - GO:0019538//protein metabolic process gi|111607469|ref|NP_001036175.1|/2.18495e-155/serine protease 57 precursor [Mus musculus] 67157 2133 3.433333333 4.823333333 0.490420584 Up 0.485492121 2610301B20Rik RIKEN cDNA 2610301B20 gene - - - - gi|165905593|ref|NP_080281.3|/1.736e-104/protein C8orf37 homolog [Mus musculus] 56534 781 6.453333333 8.383333333 0.377479447 Up 0.485398097 Hspb3 heat shock protein 3 K09544|1|2e-83|310|mmu:56534|heat shock protein beta-3 GO:0043231//intracellular membrane-bounded organelle - GO:0050896//response to stimulus gi|9910272|ref|NP_064344.1|/1.57691e-82/heat shock protein beta-3 [Mus musculus] 216831 4099 14.00333333 17.28666667 0.30388942 Up 0.485200647 Arhgap44 Rho GTPase activating protein 44 K19269|1|1e-115|421|pbi:103065057|phosphoglycolate phosphatase [EC:3.1.3.18 3.1.3.48];K13709|2|1e-21|108|mze:101477658|Rho GTPase-activating protein 5;K20315|3|2e-21|107|pbi:103056452|Rho GTPase-activating protein 21/23 GO:0005622//intracellular - - gi|34328406|ref|NP_778168.2|/0/rho GTPase-activating protein 44 isoform 2 [Mus musculus] 78829 2349.64 104.8033333 123.79 0.240210172 Up 0.484890368 Tsc22d4 "TSC22 domain family, member 4" - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated;GO:0006950//response to stress;GO:0006950//response to stress" gi|356995846|ref|NP_084081.1|/0/TSC22 domain family protein 4 isoform 1 [Mus musculus] 12702 2742 2.06 3.18 0.626382428 Up 0.484730528 Socs3 suppressor of cytokine signaling 3 K04696|1|1e-116|423|mmu:12702|suppressor of cytokine signaling 3 GO:0044444//cytoplasmic part GO:0019887//protein kinase regulator activity;GO:0005488//binding GO:0008286//insulin receptor signaling pathway;GO:0040007//growth;GO:0001568//blood vessel development;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0043627//response to estrogen;GO:0007259//JAK-STAT cascade;GO:0006915//apoptotic process;GO:0001933//negative regulation of protein phosphorylation;GO:0009887//organ morphogenesis;GO:0032446//protein modification by small protein conjugation;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0031960//response to corticosteroid;GO:0010212//response to ionizing radiation;GO:0006950//response to stress;GO:0002237//response to molecule of bacterial origin;GO:0048598//embryonic morphogenesis;GO:0031667//response to nutrient levels gi|589955414|ref|XP_006990326.1|/1.01353e-115/PREDICTED: suppressor of cytokine signaling 3 [Peromyscus maniculatus bairdii] 21427 1436 24.5 29.50333333 0.268096212 Up 0.484692918 Vps72 vacuolar protein sorting 72 K11664|1|4e-179|630|mmu:21427|vacuolar protein sorting-associated protein 72 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0019827//stem cell population maintenance;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" gi|83921607|ref|NP_033362.2|/3.16196e-178/vacuolar protein sorting-associated protein 72 homolog [Mus musculus] 16195 5452 37.34 31.09666667 -0.263961985 Down 0.484533078 Il6st interleukin 6 signal transducer K05060|1|0.0|1694|mmu:16195|interleukin 6 signal transducer GO:0009986//cell surface;GO:0043005//neuron projection;GO:0005887//integral component of plasma membrane;GO:0043025//neuronal cell body;GO:0044421 GO:0004897//ciliary neurotrophic factor receptor activity;GO:0005126//cytokine receptor binding;GO:0019838//growth factor binding;GO:0046983//protein dimerization activity GO:0006641//triglyceride metabolic process;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0045687//positive regulation of glial cell differentiation;GO:0031667//response to nutrient levels;GO:0001649//osteoblast differentiation;GO:0007219//Notch signaling pathway;GO:0006073//cellular glucan metabolic process;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0014909//smooth muscle cell migration;GO:0042098//T cell proliferation;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0051480//regulation of cytosolic calcium ion concentration gi|225007625|ref|NP_034690.3|/0/interleukin-6 receptor subunit beta precursor [Mus musculus] 18764 5221 5.226666667 3.783333333 -0.466233262 Down 0.484222799 Pkd2 polycystic kidney disease 2 K04986|1|0.0|1390|mmu:18764|polycystin 2 GO:0031252//cell leading edge;GO:0005884//actin filament;GO:0016323//basolateral plasma membrane;GO:0072372//primary cilium;GO:0030054//cell junction;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0044448 GO:0005272//sodium channel activity;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding;GO:0019899//enzyme binding;GO:0005244//voltage-gated ion channel activity GO:0001701//in utero embryonic development;GO:0006814//sodium ion transport;GO:0006809//nitric oxide biosynthetic process;GO:0048754//branching morphogenesis of an epithelial tube;GO:0009612//response to mechanical stimulus;GO:0001656//metanephros development;GO:0031657//regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0009967//positive regulation of signal transduction;GO:0001889//liver development;GO:0006970//response to osmotic stress;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0046058//cAMP metabolic process;GO:0048844//artery morphogenesis;GO:0000302//response to reactive oxygen species;GO:0072021;GO:0007050//cell cycle arrest;GO:0001657//ureteric bud development;GO:0051283//negative regulation of sequestering of calcium ion;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0072059;GO:0033554//cellular response to stress;GO:0006366//transcription from RNA polymerase II promoter;GO:0003143//embryonic heart tube morphogenesis;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0072050//S-shaped body morphogenesis;GO:0072164//mesonephric tubule development;GO:0072017//distal tubule development;GO:0007098//centrosome cycle;GO:0007368//determination of left/right symmetry gi|164519057|ref|NP_032887.3|/0/polycystin-2 [Mus musculus] 213673 2467 47.52333333 56.44333333 0.248167159 Up 0.484213397 9530068E07Rik RIKEN cDNA 9530068E07 gene - GO:0016020//membrane - - gi|58037541|ref|NP_694757.1|/2.99009e-103/keratinocyte-associated transmembrane protein 2 precursor [Mus musculus] 67279 1179 5.226666667 6.943333333 0.40973728 Up 0.484128775 Med31 mediator complex subunit 31 K15153|1|8e-70|266|pps:100969108|mediator of RNA polymerase II transcription subunit 31 GO:0043234//protein complex;GO:0031981//nuclear lumen "GO:0005515//protein binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" GO:0065003;GO:0006366//transcription from RNA polymerase II promoter gi|725576282|ref|XP_010340256.1|/1.38974e-69/PREDICTED: mediator of RNA polymerase II transcription subunit 31 isoform X1 [Saimiri boliviensis boliviensis] 64685 1335.29 5.163333333 6.883333333 0.414804638 Up 0.484128775 Nmi N-myc (and STAT) interactor K15261|1|2e-08|63.2|crg:105332066|poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - - gi|33469125|ref|NP_062274.1|/6.84076e-167/N-myc-interactor [Mus musculus] 104307 150 0.01 0.416666667 5.380821784 Up 0.483978337 Rnu12 "RNA U12, small nuclear" - - - - - 228136 4740 37.5 31.35666667 -0.258118392 Down 0.483978337 Zdhhc5 "zinc finger, DHHC domain containing 5" K20030|1|0.0|1266|mmu:228136|palmitoyltransferase ZDHHC5/8 [EC:2.3.1.225] GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane "GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0046914//transition metal ion binding" GO:0006497//protein lipidation gi|50511087|dbj|BAD32529.1|/0/mKIAA1748 protein [Mus musculus] 67880 918 8.596666667 10.89333333 0.34159621 Up 0.483574034 Dcxr dicarbonyl L-xylulose reductase K03331|1|3e-126|453|mmu:67880|L-xylulose reductase [EC:1.1.1.10] GO:0030141//secretory granule;GO:0005874//microtubule;GO:0042995//cell projection;GO:0016020//membrane "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0036094//small molecule binding;GO:0016651//oxidoreductase activity, acting on NAD(P)H" GO:0019318//hexose metabolic process;GO:0051260//protein homooligomerization;GO:0019321;GO:0046496//nicotinamide nucleotide metabolic process gi|146134409|ref|NP_080704.2|/2.03068e-125/L-xylulose reductase [Mus musculus] 232232 2494 10.55 13.17666667 0.320742456 Up 0.483291963 Hdac11 histone deacetylase 11 K11418|1|0.0|706|mmu:232232|histone deacetylase 11 [EC:3.5.1.98] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0016020//membrane GO:0017136//NAD-dependent histone deacetylase activity;GO:0005515//protein binding "GO:0016575//histone deacetylation;GO:0021782//glial cell development;GO:0006351//transcription, DNA-templated" gi|21450317|ref|NP_659168.1|/0/histone deacetylase 11 [Mus musculus] 74504 2028 18.99666667 23.11333333 0.282979044 Up 0.483216744 Fam53a "family with sequence similarity 53, member A" - GO:0043231//intracellular membrane-bounded organelle - GO:0006886//intracellular protein transport "gi|148705473|gb|EDL37420.1|/0/RIKEN cDNA 2410018C17, isoform CRA_a [Mus musculus]" 17906 633 13507.18667 11519.61333 -0.229634923 Down 0.483160329 Myl2 "myosin, light polypeptide 2, regulatory, cardiac, slow" K10351|1|1e-90|334|mmu:17906|myosin regulatory light chain 2 GO:0030016//myofibril;GO:0015629//actin cytoskeleton GO:0046872//metal ion binding;GO:0003779//actin binding GO:0003015//heart process;GO:0006941//striated muscle contraction;GO:0016049//cell growth;GO:0030239//myofibril assembly;GO:0003208//cardiac ventricle morphogenesis;GO:0001708//cell fate specification "gi|568936906|ref|XP_006530249.1|/5.76436e-99/PREDICTED: myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform X1 [Mus musculus]" 215705 1711.72 4.366666667 3.063333333 -0.511430045 Down 0.482756027 Arrdc1 arrestin domain containing 1 - - - - "gi|13278612|gb|AAH04091.1|/0/Arrdc1 protein, partial [Mus musculus]" 224824 3214 16.02 19.56333333 0.28827806 Up 0.482605589 Pex6 peroxisomal biogenesis factor 6 K13339|1|0.0|1642|mmu:224824|peroxin-6 GO:0044439 GO:0032550;GO:0005515//protein binding;GO:0016887//ATPase activity GO:0031647//regulation of protein stability;GO:0016558//protein import into peroxisome matrix;GO:0009154//purine ribonucleotide catabolic process gi|21703962|ref|NP_663463.1|/0/peroxisome assembly factor 2 [Mus musculus] 329252 3623 5.506666667 4.02 -0.45398378 Down 0.482558577 Lgr6 leucine-rich repeat-containing G protein-coupled receptor 6 K08399|1|0.0|1714|mmu:329252|leucine-rich repeat-containing G protein-coupled receptor 6 - - - - 319757 3977 4.013333333 5.5 0.454630632 Up 0.482558577 Smo "smoothened, frizzled class receptor" K06226|1|0.0|1492|mmu:319757|smoothened - - - gi|171543835|ref|NP_795970.3|/0/smoothened homolog precursor [Mus musculus] 67819 3145 18.73666667 22.8 0.28316951 Up 0.482483358 Derl1 "Der1-like domain family, member 1" K11519|1|2e-138|496|rno:362912|Derlin-1 - - - - 12931 1671 1.753333333 0.9 -0.962103392 Down 0.482191884 Crlf1 cytokine receptor-like factor 1 K05060|1|4e-23|112|cmk:103177817|interleukin 6 signal transducer - - - - 12333 3084.89 18.80333333 22.83 0.279942423 Up 0.482126067 Capn1 calpain 1 K01367|1|0.0|1437|mmu:12333|calpain-1 [EC:3.4.22.52] GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0044424 GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004197//cysteine-type endopeptidase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004197//cysteine-type endopeptidase activity GO:0009057//macromolecule catabolic process;GO:0016485//protein processing;GO:0009057//macromolecule catabolic process;GO:0016485//protein processing gi|6671668|ref|NP_031626.1|/0/calpain-1 catalytic subunit [Mus musculus] 108660 1971 80.93 95.79 0.243200458 Up 0.482013239 Rnf187 ring finger protein 187 K15709|1|2e-101|372|mmu:108660|E3 ubiquitin-protein ligase RNF187 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0019787//ubiquitin-like protein transferase activity "GO:0006511//ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation" gi|7259250|dbj|BAA92754.1|/1.37819e-100/unnamed protein product [Mus musculus] 102462 915 23.10666667 27.77666667 0.265564326 Up 0.481618338 Imp3 "IMP3, U3 small nucleolar ribonucleoprotein" K14560|1|9e-79|295|mmu:102462|U3 small nucleolar ribonucleoprotein protein IMP3 - - - - 19263 11912 16.42333333 13.31333333 -0.302875139 Down 0.481561924 Ptprb "protein tyrosine phosphatase, receptor type, B" K05694|1|0.0|3919|mmu:19263|receptor-type tyrosine-protein phosphatase beta [EC:3.1.3.48] GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0004721//phosphoprotein phosphatase activity GO:0048646//anatomical structure formation involved in morphogenesis;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|258613900|ref|NP_084204.2|/0/receptor-type tyrosine-protein phosphatase beta precursor [Mus musculus] 56233 4229.58 27.56333333 22.90333333 -0.267192787 Down 0.481524315 Hdac7 histone deacetylase 7 K11408|1|0.0|1320|ptr:466968|histone deacetylase 7 [EC:3.5.1.98] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0043169//cation binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0043169//cation binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0043169//cation binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0043169//cation binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0043169//cation binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0043169//cation binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0043169//cation binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0008134//transcription factor binding GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0014706//striated muscle tissue development;GO:0001818//negative regulation of cytokine production;GO:0016575//histone deacetylation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0034329//cell junction assembly;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030098//lymphocyte differentiation;GO:0006952//defense response;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0014706//striated muscle tissue development;GO:0001818//negative regulation of cytokine production;GO:0016575//histone deacetylation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0034329//cell junction assembly;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030098//lymphocyte differentiation;GO:0006952//defense response;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0014706//striated muscle tissue development;GO:0001818//negative regulation of cytokine production;GO:0016575//histone deacetylation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0034329//cell junction assembly;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030098//lymphocyte differentiation;GO:0006952//defense response;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0014706//striated muscle tissue development;GO:0001818//negative regulation of cytokine production;GO:0016575//histone deacetylation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0034329//cell junction assembly;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030098//lymphocyte differentiation;GO:0006952//defense response;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0014706//striated muscle tissue development;GO:0001818//negative regulation of cytokine production;GO:0016575//histone deacetylation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0034329//cell junction assembly;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030098//lymphocyte differentiation;GO:0006952//defense response;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0014706//striated muscle tissue development;GO:0001818//negative regulation of cytokine production;GO:0016575//histone deacetylation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0034329//cell junction assembly;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030098//lymphocyte differentiation;GO:0006952//defense response;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0014706//striated muscle tissue development;GO:0001818//negative regulation of cytokine production;GO:0016575//histone deacetylation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0034329//cell junction assembly;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030098//lymphocyte differentiation;GO:0006952//defense response gi|568992931|ref|XP_006521266.1|/0/PREDICTED: histone deacetylase 7 isoform X4 [Mus musculus] 231803 3191 15.36333333 18.84333333 0.294562929 Up 0.481449095 Mepce methylphosphate capping enzyme K15190|1|0.0|1007|mmu:231803|7SK snRNA methylphosphate capping enzyme [EC:2.1.1.-] - GO:0008168//methyltransferase activity GO:0034660//ncRNA metabolic process;GO:1901992//positive regulation of mitotic cell cycle phase transition;GO:0035561//regulation of chromatin binding;GO:0009451//RNA modification gi|119672920|ref|NP_659162.3|/0/7SK snRNA methylphosphate capping enzyme [Mus musculus] 664994 1088 29.67 35.40666667 0.255016102 Up 0.481298657 Isoc2a isochorismatase domain containing 2a K04432|1|7e-10|67.4|tsp:Tsp_02206|mitogen-activated protein kinase kinase 3 [EC:2.7.12.2] - - - - 22173 5894 2.276666667 3.42 0.587073247 Up 0.481251645 Tyr tyrosinase K00505|1|0.0|1015|mmu:22173|tyrosinase [EC:1.14.18.1] - - - - 319742 1035 0.346666667 1.02 1.556948125 Up 0.481120012 Mpzl3 myelin protein zero-like 3 K06770|1|3e-26|121|xtr:780198|myelin protein zero GO:0031224//intrinsic component of membrane - GO:0043062//extracellular structure organization;GO:0042303//molting cycle "gi|148693686|gb|EDL25633.1|/2.65899e-135/RIKEN cDNA A530065I17, isoform CRA_b, partial [Mus musculus]" 56403 4376.19 14.51 11.69 -0.31177259 Down 0.480997781 Syncrip "synaptotagmin binding, cytoplasmic RNA interacting protein" K13160|1|0.0|855|mmu:56403|heterogeneous nuclear ribonucleoprotein Q GO:0043234//protein complex;GO:0005681//spliceosomal complex;GO:0043234//protein complex;GO:0005681//spliceosomal complex;GO:0043234//protein complex;GO:0005681//spliceosomal complex GO:0003729//mRNA binding;GO:0003729//mRNA binding;GO:0003729//mRNA binding GO:0006412//translation;GO:0006396//RNA processing;GO:0048255//mRNA stabilization;GO:0034341//response to interferon-gamma;GO:0006412//translation;GO:0006396//RNA processing;GO:0048255//mRNA stabilization;GO:0034341//response to interferon-gamma;GO:0006412//translation;GO:0006396//RNA processing;GO:0048255//mRNA stabilization;GO:0034341//response to interferon-gamma "gi|62087776|dbj|BAD92335.1|/0/synaptotagmin binding, cytoplasmic RNA interacting protein variant [Homo sapiens]" 107173 1650.52 22.00333333 26.6 0.273704148 Up 0.480809733 Gpr137 G protein-coupled receptor 137 K02158|1|1e-08|64.3|rno:64639|Bcl-2-antagonist of cell death GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|293629314|ref|NP_001170832.1|/8.26436e-171/integral membrane protein GPR137 isoform 3 [Mus musculus] 100504249 518 2.133333333 1.213333333 -0.814133455 Down 0.480452443 Gm15350 predicted gene 15350 K01530|1|1e-14|80.9|pale:102884486|phospholipid-translocating ATPase [EC:3.6.3.1] - - - - 17472 4475 2.3 3.44 0.580774704 Up 0.480320809 Gbp4 guanylate binding protein 4 K17339|1|2e-07|62.0|ame:550886|atlastin [EC:3.6.5.-] GO:0031982//vesicle;GO:0031982//vesicle;GO:0020003//symbiont-containing vacuole GO:0005488//binding;GO:0005488//binding GO:0032496//response to lipopolysaccharide;GO:0001562//response to protozoan;GO:0042742//defense response to bacterium;GO:0002697;GO:0001932//regulation of protein phosphorylation;GO:0016567//protein ubiquitination;GO:0032480//negative regulation of type I interferon production;GO:0034341//response to interferon-gamma;GO:0006606//protein import into nucleus;GO:0032496//response to lipopolysaccharide;GO:0001562//response to protozoan;GO:0042742//defense response to bacterium;GO:0002697;GO:0001932//regulation of protein phosphorylation;GO:0016567//protein ubiquitination;GO:0032480//negative regulation of type I interferon production;GO:0034341//response to interferon-gamma;GO:0051702//interaction with symbiont;GO:0006606//protein import into nucleus gi|365192570|ref|NP_001242934.1|/0/macrophage activation 2 isoform 1 [Mus musculus] 224792 8535 48.48666667 40.81333333 -0.248547531 Down 0.48024559 Adgrf5 adhesion G protein-coupled receptor F5 K08458|1|0.0|2580|mmu:224792|G protein-coupled receptor 116 GO:0031224//intrinsic component of membrane - GO:0006629//lipid metabolic process;GO:0030154//cell differentiation;GO:0033500//carbohydrate homeostasis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0015980//energy derivation by oxidation of organic compounds gi|124487171|ref|NP_001074647.1|/0/adhesion G protein-coupled receptor F5 precursor [Mus musculus] 19025 3451.12 69.62 82.26333333 0.240747717 Up 0.48004814 Ctsa cathepsin A K13289|1|0.0|979|mmu:19025|cathepsin A (carboxypeptidase C) [EC:3.4.16.5] GO:0000323//lytic vacuole;GO:0000323//lytic vacuole GO:0005488//binding;GO:0004180//carboxypeptidase activity;GO:0005488//binding;GO:0004180//carboxypeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process gi|84042525|ref|NP_032932.2|/0/lysosomal protective protein isoform a preproprotein [Mus musculus] 69597 3086 81.31 68.84333333 -0.240115842 Down 0.479831885 Afg3l2 AFG3-like AAA ATPase 2 K08956|1|0.0|1428|mmu:69597|AFG3 family protein [EC:3.4.24.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane GO:0016462//pyrophosphatase activity;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0032550 GO:0048741//skeletal muscle fiber development;GO:0060004//reflex;GO:0009057//macromolecule catabolic process;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0016485//protein processing;GO:0007007//inner mitochondrial membrane organization;GO:0008366//axon ensheathment;GO:0035264//multicellular organism growth gi|110625761|ref|NP_081406.1|/0/AFG3-like protein 2 [Mus musculus] 19819 1472 3.73 5.146666667 0.464462716 Up 0.479596826 Rnaseh1 ribonuclease H1 K03469|1|3e-138|494|rno:298933|ribonuclease HI [EC:3.1.26.4] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0097159//organic cyclic compound binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0097159//organic cyclic compound binding;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0097159//organic cyclic compound binding" GO:0006261//DNA-dependent DNA replication;GO:0006261//DNA-dependent DNA replication;GO:0006261//DNA-dependent DNA replication gi|226246542|ref|NP_035405.2|/3.78345e-142/ribonuclease H1 isoform 1 precursor [Mus musculus] 13852 2937 7.423333333 5.663333333 -0.390415706 Down 0.479578021 Stx2 syntaxin 2 K08486|1|3e-129|465|mmu:13852|syntaxin 1B/2/3 "GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0043234//protein complex;GO:0044459;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0043234//protein complex;GO:0044459;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0043234//protein complex;GO:0044459;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0016192//vesicle-mediated transport;GO:0030154//cell differentiation;GO:0032506//cytokinetic process;GO:0007275//multicellular organism development;GO:0009653//anatomical structure morphogenesis;GO:0015031//protein transport;GO:0007338//single fertilization;GO:0030031//cell projection assembly;GO:0016192//vesicle-mediated transport;GO:0030154//cell differentiation;GO:0032506//cytokinetic process;GO:0007275//multicellular organism development;GO:0009653//anatomical structure morphogenesis;GO:0015031//protein transport;GO:0007338//single fertilization;GO:0030031//cell projection assembly;GO:0016192//vesicle-mediated transport;GO:0030154//cell differentiation;GO:0032506//cytokinetic process;GO:0007275//multicellular organism development;GO:0009653//anatomical structure morphogenesis;GO:0015031//protein transport;GO:0007338//single fertilization;GO:0030031//cell projection assembly gi|553727119|ref|NP_001272962.1|/6.8395e-124/syntaxin-2 isoform b [Mus musculus] 239719 8281 7.443333333 5.68 -0.390057916 Down 0.479578021 Mkl2 MKL/myocardin-like 2 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0008092//cytoskeletal protein binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0008092//cytoskeletal protein binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0008092//cytoskeletal protein binding;GO:0003712//transcription cofactor activity;GO:0097159//organic cyclic compound binding;GO:0001071//nucleic acid binding transcription factor activity GO:0042692//muscle cell differentiation;GO:0007507//heart development;GO:0009887//organ morphogenesis;GO:0014706//striated muscle tissue development;GO:0001568//blood vessel development;GO:0006366//transcription from RNA polymerase II promoter;GO:0009790//embryo development;GO:0042692//muscle cell differentiation;GO:0007507//heart development;GO:0009887//organ morphogenesis;GO:0014706//striated muscle tissue development;GO:0001568//blood vessel development;GO:0006366//transcription from RNA polymerase II promoter;GO:0009790//embryo development;GO:0042692//muscle cell differentiation;GO:0007507//heart development;GO:0009887//organ morphogenesis;GO:0014706//striated muscle tissue development;GO:0001568//blood vessel development;GO:0006366//transcription from RNA polymerase II promoter;GO:0009790//embryo development gi|32469513|ref|NP_862908.1|/3.13915e-52/MKL/myocardin-like protein 2 isoform 2 [Mus musculus] 432855 2487 2.413333333 1.443333333 -0.741622672 Down 0.479371169 Zfhx2os "zinc finger homeobox 2, opposite strand" K09379|1|0.0|694|mmu:239102|zinc finger homeobox protein 2 - - - - 75573 789 0.516666667 1.226666667 1.247437551 Up 0.478713002 Prr29 proline rich 29 - - - - gi|256000809|ref|NP_083621.1|/3.32694e-96/proline-rich protein 29 [Mus musculus] 20536 4441 73.90333333 62.39333333 -0.24424755 Down 0.478393321 Slc4a3 "solute carrier family 4 (anion exchanger), member 3" "K13856|1|0.0|1868|mmu:20536|solute carrier family 4 (anion exchanger), member 3" GO:0016021//integral component of membrane GO:0015301//anion:anion antiporter activity GO:0015711//organic anion transport;GO:0030641//regulation of cellular pH gi|165377246|ref|NP_033234.2|/0/anion exchange protein 3 [Mus musculus] 68276 2008 2.943333333 4.2 0.512938391 Up 0.478355711 Toe1 "target of EGR1, member 1 (nuclear)" K13202|1|0.0|957|mmu:68276|target of EGR1 protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - gi|21311839|ref|NP_080930.1|/0/target of EGR1 protein 1 [Mus musculus] 12977 4023.21 12.90666667 15.88333333 0.299397262 Up 0.478299297 Csf1 colony stimulating factor 1 (macrophage) K05453|1|0.0|991|mmu:12977|macrophage colony-stimulating factor 1 GO:0016021//integral component of membrane;GO:0043234//protein complex;GO:0044421;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0044421;GO:0044444//cytoplasmic part;GO:0016021//integral component of membrane;GO:0043234//protein complex;GO:0044421;GO:0044444//cytoplasmic part GO:0005126//cytokine receptor binding;GO:0042802//identical protein binding;GO:0005126//cytokine receptor binding;GO:0042802//identical protein binding;GO:0005126//cytokine receptor binding;GO:0042802//identical protein binding GO:0001934//positive regulation of protein phosphorylation;GO:0030879//mammary gland development;GO:0007265//Ras protein signal transduction;GO:0010742//macrophage derived foam cell differentiation;GO:0001952//regulation of cell-matrix adhesion;GO:0010467//gene expression;GO:0060560//developmental growth involved in morphogenesis;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0001503//ossification;GO:0042475//odontogenesis of dentin-containing tooth;GO:0048754//branching morphogenesis of an epithelial tube;GO:0035264//multicellular organism growth;GO:0006952//defense response;GO:0022414//reproductive process;GO:0016477//cell migration;GO:0032943//mononuclear cell proliferation;GO:0001894//tissue homeostasis;GO:0001934//positive regulation of protein phosphorylation;GO:0030879//mammary gland development;GO:0007265//Ras protein signal transduction;GO:0002274;GO:0010742//macrophage derived foam cell differentiation;GO:0001952//regulation of cell-matrix adhesion;GO:0010467//gene expression;GO:0060560//developmental growth involved in morphogenesis;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0001503//ossification;GO:0042475//odontogenesis of dentin-containing tooth;GO:0048754//branching morphogenesis of an epithelial tube;GO:0035264//multicellular organism growth;GO:0006952//defense response;GO:0022414//reproductive process;GO:0016477//cell migration;GO:0032943//mononuclear cell proliferation;GO:0001894//tissue homeostasis;GO:0001934//positive regulation of protein phosphorylation;GO:0030879//mammary gland development;GO:0007265//Ras protein signal transduction;GO:0010742//macrophage derived foam cell differentiation;GO:0001952//regulation of cell-matrix adhesion;GO:0010467//gene expression;GO:0060560//developmental growth involved in morphogenesis;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0001503//ossification;GO:0042475//odontogenesis of dentin-containing tooth;GO:0048754//branching morphogenesis of an epithelial tube;GO:0035264//multicellular organism growth;GO:0006952//defense response;GO:0022414//reproductive process;GO:0016477//cell migration;GO:0032943//mononuclear cell proliferation;GO:0001894//tissue homeostasis gi|74206703|dbj|BAE41601.1|/0/unnamed protein product [Mus musculus] 20620 2802 15.74666667 12.76333333 -0.303041305 Down 0.478299297 Plk2 polo-like kinase 2 K08861|1|0.0|1297|cge:100753472|polo-like kinase 2 [EC:2.7.11.21] GO:0043005//neuron projection;GO:0005813//centrosome GO:0032550;GO:0060089;GO:0004672//protein kinase activity GO:0007265//Ras protein signal transduction;GO:0000075//cell cycle checkpoint;GO:0007099//centriole replication;GO:0007611//learning or memory;GO:0044772//mitotic cell cycle phase transition;GO:0048167//regulation of synaptic plasticity;GO:0006915//apoptotic process;GO:0006796//phosphate-containing compound metabolic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0031331;GO:0006464//cellular protein modification process gi|625183267|ref|XP_003496249.2|/0/PREDICTED: serine/threonine-protein kinase PLK2 [Cricetulus griseus] 320092 1085 1.75 2.78 0.667729961 Up 0.478242882 E030003E18Rik RIKEN cDNA E030003E18 gene - - - - - 67809 2252 8.046666667 10.21333333 0.343990621 Up 0.478111249 Rmdn3 regulator of microtubule dynamics 3 - GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane;GO:0015630//microtubule cytoskeleton - GO:0012501//programmed cell death;GO:0048869//cellular developmental process;GO:0006875//cellular metal ion homeostasis "gi|33585791|gb|AAH55754.1|/0/Family with sequence similarity 82, member A2, partial [Mus musculus]" 21379 2696.04 43.89 36.91333333 -0.249750249 Down 0.477424875 Tbrg4 transforming growth factor beta regulated gene 4 K18190|1|2e-22|110|lcm:102347920|FAST kinase domain-containing protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016301//kinase activity;GO:0016301//kinase activity GO:0006464//cellular protein modification process;GO:0015980//energy derivation by oxidation of organic compounds;GO:0006464//cellular protein modification process;GO:0015980//energy derivation by oxidation of organic compounds "gi|148669288|gb|EDL01235.1|/0/mCG21397, isoform CRA_a, partial [Mus musculus]" 24004 2234.19 36.39333333 43.36333333 0.252801464 Up 0.477387265 Rai2 retinoic acid induced 2 - - - - gi|157266275|ref|NP_940801.2|/0/retinoic acid-induced protein 2 [Mus musculus] 11796 2820 2.94 4.186666667 0.509985903 Up 0.476982963 Birc3 baculoviral IAP repeat-containing 3 K16060|1|0.0|1142|mmu:11796|baculoviral IAP repeat-containing protein 2/3 - - - - 11677 1402 176.83 207.69 0.232068699 Up 0.476663282 Akr1b3 "aldo-keto reductase family 1, member B3 (aldose reductase)" K00011|1|3e-176|620|mmu:11677|aldehyde reductase [EC:1.1.1.21] GO:0031981//nuclear lumen;GO:0044421 "GO:0016903//oxidoreductase activity, acting on the aldehyde or oxo group of donors;GO:0008106//alcohol dehydrogenase (NADP+) activity" GO:0030647;GO:0007259//JAK-STAT cascade;GO:0042221//response to chemical;GO:0006060//sorbitol metabolic process;GO:0008284//positive regulation of cell proliferation gi|160707894|ref|NP_033788.3|/2.42236e-175/aldose reductase [Mus musculus] 30933 1550 4.326666667 5.826666667 0.429414802 Up 0.476597465 Tor2a "torsin family 2, member A" "K01056|1|3e-40|168|tgu:100227249|peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]" GO:0044432;GO:0044432 GO:0032550;GO:0005102//receptor binding;GO:0016462//pyrophosphatase activity;GO:0032550;GO:0005102//receptor binding;GO:0016462//pyrophosphatase activity GO:0051084//'de novo' posttranslational protein folding;GO:0051259//protein oligomerization;GO:0051084//'de novo' posttranslational protein folding;GO:0051259//protein oligomerization gi|22779883|ref|NP_690013.1|/6.14039e-145/torsin-2A precursor [Mus musculus] 230098 1650 0.183333333 0.763333333 2.057844075 Up 0.47638121 Arhgef39 Rho guanine nucleotide exchange factor (GEF) 39 "K05724|1|3e-11|72.8|aqu:105312012|FYVE, RhoGEF and PH domain containing 5/6" GO:0044464;GO:0016020//membrane GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding GO:0016477//cell migration;GO:0007266//Rho protein signal transduction gi|225543124|ref|NP_001013395.2|/1.15232e-166/rho guanine nucleotide exchange factor 39 [Mus musculus] 57785 845 68.24666667 57.81666667 -0.239273148 Down 0.476287186 Rangrf RAN guanine nucleotide release factor K17495|1|1e-17|92.8|bfo:BRAFLDRAFT_118449|CUB and sushi domain-containing protein GO:0031981//nuclear lumen;GO:0044291//cell-cell contact zone;GO:0031981//nuclear lumen;GO:0044291//cell-cell contact zone;GO:0031981//nuclear lumen;GO:0044291//cell-cell contact zone;GO:0031981//nuclear lumen;GO:0044291//cell-cell contact zone GO:0030695//GTPase regulator activity;GO:0017016//Ras GTPase binding;GO:0016247//channel regulator activity;GO:0030695//GTPase regulator activity;GO:0017016//Ras GTPase binding;GO:0016247//channel regulator activity;GO:0030695//GTPase regulator activity;GO:0017016//Ras GTPase binding;GO:0016247//channel regulator activity;GO:0030695//GTPase regulator activity;GO:0017016//Ras GTPase binding;GO:0016247//channel regulator activity GO:0019222//regulation of metabolic process;GO:0045184//establishment of protein localization;GO:0002028//regulation of sodium ion transport;GO:0048522;GO:0006873//cellular ion homeostasis;GO:0051169//nuclear transport;GO:0019222//regulation of metabolic process;GO:0045184//establishment of protein localization;GO:0002028//regulation of sodium ion transport;GO:0048522;GO:0006873//cellular ion homeostasis;GO:0051169//nuclear transport;GO:0019222//regulation of metabolic process;GO:0045184//establishment of protein localization;GO:0002028//regulation of sodium ion transport;GO:0048522;GO:0006873//cellular ion homeostasis;GO:0051169//nuclear transport;GO:0019222//regulation of metabolic process;GO:0045184//establishment of protein localization;GO:0002028//regulation of sodium ion transport;GO:0048522;GO:0006873//cellular ion homeostasis;GO:0051169//nuclear transport gi|549806791|ref|NP_001272371.1|/1.85222e-100/ran guanine nucleotide release factor isoform 3 [Mus musculus] 66172 903 4.843333333 6.45 0.413298863 Up 0.476268382 Med11 mediator complex subunit 11 K15131|1|3e-59|230|ngi:103752184|mediator of RNA polymerase II transcription subunit 11 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0005488//binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" GO:0006366//transcription from RNA polymerase II promoter gi|674092008|ref|XP_008854114.1|/2.72775e-58/PREDICTED: mediator of RNA polymerase II transcription subunit 11 [Nannospalax galili] 17907 755 0.21 0.813333333 1.953457414 Up 0.475892286 Mylpf "myosin light chain, phosphorylatable, fast skeletal muscle" K12758|1|5e-95|349|aml:100480191|fast skeletal myosin light chain 2 GO:0015629//actin cytoskeleton GO:0046872//metal ion binding;GO:0005198//structural molecule activity GO:0014706//striated muscle tissue development;GO:0002376//immune system process;GO:0003012//muscle system process "gi|562838033|ref|XP_006148229.1|/7.54834e-95/PREDICTED: myosin regulatory light chain 2, skeletal muscle isoform isoform X1 [Tupaia chinensis]" 230157 2442 2.23 3.343333333 0.58424349 Up 0.475864079 Tmeff1 transmembrane protein with EGF-like and two follistatin-like domains 1 K06254|1|3e-23|113|cin:100187262|agrin GO:0031224//intrinsic component of membrane - GO:0032502//developmental process "gi|148670383|gb|EDL02330.1|/0/transmembrane protein with EGF-like and two follistatin-like domains 1, isoform CRA_b, partial [Mus musculus]" 12655 1539 0.036666667 0.49 3.740240726 Up 0.475666629 Chil3 chitinase-like 3 K17524|1|0.0|829|mmu:12655|chitinase 3-like 3/4;K01183|4|6e-165|583|cfa:479904|chitinase [EC:3.2.1.14] - - - - 140580 5576 5.016666667 3.64 -0.462790631 Down 0.475657227 Elmo1 engulfment and cell motility 1 K12366|1|4e-130|469|ocu:100352081|engulfment and cell motility protein 1 - - - - 71772 3595 25.36 30.33666667 0.258507828 Up 0.475572605 Plbd2 phospholipase B domain containing 2 - GO:0000323//lytic vacuole GO:0003824//catalytic activity GO:0006629//lipid metabolic process "gi|258588286|pdb|3FGW|A/0/Chain A, One Chain Form Of The 66.3 Kda Protein" 14199 2373.88 55.88666667 65.85333333 0.236752339 Up 0.475299936 Fhl1 four and a half LIM domains 1 K14365|1|3e-180|634|mmu:14199|four and a half LIM domains protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0048869//cellular developmental process;GO:0016049//cell growth;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006813//potassium ion transport;GO:0032412//regulation of ion transmembrane transporter activity;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0048869//cellular developmental process;GO:0016049//cell growth;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006813//potassium ion transport;GO:0032412//regulation of ion transmembrane transporter activity;GO:0048513//animal organ development;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0009653//anatomical structure morphogenesis;GO:0048869//cellular developmental process;GO:0016049//cell growth;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006813//potassium ion transport;GO:0032412//regulation of ion transmembrane transporter activity;GO:0048513//animal organ development;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0009653//anatomical structure morphogenesis;GO:0048869//cellular developmental process;GO:0016049//cell growth;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006813//potassium ion transport;GO:0032412//regulation of ion transmembrane transporter activity;GO:0048513//animal organ development;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0009653//anatomical structure morphogenesis gi|116517336|ref|NP_001070830.1|/0/four and a half LIM domains protein 1 isoform 2 [Mus musculus] 53871 2296.34 1.813333333 2.843333333 0.64893909 Up 0.475271729 Pkd2l2 polycystic kidney disease 2-like 2 K04991|1|0.0|1073|mmu:53871|polycystin 2L2 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0006811//ion transport;GO:0006811//ion transport gi|253314500|ref|NP_058623.2|/0/polycystic kidney disease 2-like 2 protein [Mus musculus] 71361 2753.08 17.37 14.21 -0.289691199 Down 0.475234119 Aifm2 "apoptosis-inducing factor, mitochondrion-associated 2" K04727|1|8e-09|64.3|aqu:100632533|programmed cell death 8 (apoptosis-inducing factor) [EC:1.-.-.-] GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane "GO:0016649//oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor;GO:0000166//nucleotide binding;GO:0016649//oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor;GO:0000166//nucleotide binding;GO:0016649//oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor;GO:0000166//nucleotide binding;GO:0016649//oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor;GO:0000166//nucleotide binding" GO:0012502//induction of programmed cell death;GO:0044710;GO:0051276//chromosome organization;GO:0012502//induction of programmed cell death;GO:0044710;GO:0051276//chromosome organization;GO:0012502//induction of programmed cell death;GO:0044710;GO:0051276//chromosome organization;GO:0012502//induction of programmed cell death;GO:0044710;GO:0051276//chromosome organization gi|564397948|ref|XP_006256515.1|/0/PREDICTED: apoptosis-inducing factor 2 isoform X2 [Rattus norvegicus] 21333 1034 1.626666667 0.816666667 -0.994099399 Down 0.475177705 Tac1 tachykinin 1 K05239|1|7e-70|266|rro:104668751|tachykinin 1 - - - gi|724864923|ref|XP_010369825.1|/7.31016e-66/PREDICTED: protachykinin-1 isoform X2 [Rhinopithecus roxellana] 18627 5845 7.673333333 5.913333333 -0.375881824 Down 0.475168303 Per2 period circadian clock 2 K02633|1|0.0|2302|mmu:18627|period circadian protein GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0060089 GO:0048511//rhythmic process;GO:0007154//cell communication;GO:0006366//transcription from RNA polymerase II promoter gi|28972163|dbj|BAC65535.1|/0/mKIAA0347 protein [Mus musculus] 68339 6292 2.08 1.19 -0.805621955 Down 0.474707586 Ccdc88c coiled-coil domain containing 88C K16536|1|5e-33|147|pale:102890902|protein HOOK3 GO:0044424 GO:0019904//protein domain specific binding;GO:0015631//tubulin binding GO:0006468//protein phosphorylation;GO:0051259//protein oligomerization;GO:0031647//regulation of protein stability;GO:0007166//cell surface receptor signaling pathway "gi|148686937|gb|EDL18884.1|/0/RIKEN cDNA 0610010D24, isoform CRA_b, partial [Mus musculus]" 12176 1756 137.4166667 160.8933333 0.227547556 Up 0.474538343 Bnip3 BCL2/adenovirus E1B interacting protein 3 K15464|1|1e-73|280|mmu:12176|BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0012505//endomembrane system;GO:0031306//intrinsic component of mitochondrial outer membrane GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0019899//enzyme binding "GO:0000266//mitochondrial fission;GO:0070997//neuron death;GO:0000737//DNA catabolic process, endonucleolytic;GO:0034614//cellular response to reactive oxygen species;GO:0009612//response to mechanical stimulus;GO:0006915//apoptotic process;GO:0010822//positive regulation of mitochondrion organization;GO:0045444//fat cell differentiation;GO:0002252;GO:0001666//response to hypoxia;GO:0012502//induction of programmed cell death;GO:0008053//mitochondrial fusion;GO:0043241//protein complex disassembly;GO:0042391//regulation of membrane potential;GO:0016568//chromatin modification;GO:0032025//response to cobalt ion;GO:0006839//mitochondrial transport;GO:0035556//intracellular signal transduction" gi|6753198|ref|NP_033890.1|/1.04838e-72/BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 [Mus musculus] 319180 431 0.4 0.01 -5.321928095 Down 0.474500733 Hist1h2bf "histone cluster 1, H2bf" K11252|1|3e-45|181|cge:100761268|histone H2B - - - - 14268 7969.38 11.91666667 9.553333333 -0.318904632 Down 0.474416112 Fn1 fibronectin 1 K05717|1|0.0|4194|ssc:397620|fibronectin 1 GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix;GO:0044459 GO:0046914//transition metal ion binding;GO:0005198//structural molecule activity;GO:0008047//enzyme activator activity;GO:0005539//glycosaminoglycan binding;GO:0019899//enzyme binding;GO:0046914//transition metal ion binding;GO:0008047//enzyme activator activity;GO:0005539//glycosaminoglycan binding;GO:0019899//enzyme binding;GO:0046914//transition metal ion binding;GO:0008047//enzyme activator activity;GO:0005539//glycosaminoglycan binding;GO:0019899//enzyme binding;GO:0046914//transition metal ion binding;GO:0008047//enzyme activator activity;GO:0005539//glycosaminoglycan binding;GO:0019899//enzyme binding;GO:0046914//transition metal ion binding;GO:0008047//enzyme activator activity;GO:0005539//glycosaminoglycan binding;GO:0019899//enzyme binding;GO:0046914//transition metal ion binding;GO:0008047//enzyme activator activity;GO:0005539//glycosaminoglycan binding;GO:0019899//enzyme binding GO:0046689//response to mercury ion;GO:0071363//cellular response to growth factor stimulus;GO:0032496//response to lipopolysaccharide;GO:0022604//regulation of cell morphogenesis;GO:0007160//cell-matrix adhesion;GO:0002526//acute inflammatory response;GO:0034695//response to prostaglandin E;GO:0006915//apoptotic process;GO:0000302//response to reactive oxygen species;GO:0034329//cell junction assembly;GO:0051345//positive regulation of hydrolase activity;GO:0000904//cell morphogenesis involved in differentiation;GO:0006935//chemotaxis;GO:0006464//cellular protein modification process;GO:0031960//response to corticosteroid;GO:0070555//response to interleukin-1;GO:0036119//response to platelet-derived growth factor;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0043062//extracellular structure organization;GO:0001678//cellular glucose homeostasis;GO:0016477//cell migration;GO:0046689//response to mercury ion;GO:0022604//regulation of cell morphogenesis;GO:0007160//cell-matrix adhesion;GO:0002526//acute inflammatory response;GO:0006915//apoptotic process;GO:0034329//cell junction assembly;GO:0051345//positive regulation of hydrolase activity;GO:0000904//cell morphogenesis involved in differentiation;GO:0006935//chemotaxis;GO:0006464//cellular protein modification process;GO:0070555//response to interleukin-1;GO:0043062//extracellular structure organization;GO:0016477//cell migration;GO:0046689//response to mercury ion;GO:0022604//regulation of cell morphogenesis;GO:0007160//cell-matrix adhesion;GO:0002526//acute inflammatory response;GO:0006915//apoptotic process;GO:0034329//cell junction assembly;GO:0051345//positive regulation of hydrolase activity;GO:0000904//cell morphogenesis involved in differentiation;GO:0006935//chemotaxis;GO:0006464//cellular protein modification process;GO:0070555//response to interleukin-1;GO:0043062//extracellular structure organization;GO:0016477//cell migration;GO:0046689//response to mercury ion;GO:0022604//regulation of cell morphogenesis;GO:0007160//cell-matrix adhesion;GO:0002526//acute inflammatory response;GO:0006915//apoptotic process;GO:0034329//cell junction assembly;GO:0051345//positive regulation of hydrolase activity;GO:0000904//cell morphogenesis involved in differentiation;GO:0006935//chemotaxis;GO:0006464//cellular protein modification process;GO:0070555//response to interleukin-1;GO:0043062//extracellular structure organization;GO:0016477//cell migration;GO:0046689//response to mercury ion;GO:0022604//regulation of cell morphogenesis;GO:0007160//cell-matrix adhesion;GO:0002526//acute inflammatory response;GO:0006915//apoptotic process;GO:0034329//cell junction assembly;GO:0051345//positive regulation of hydrolase activity;GO:0000904//cell morphogenesis involved in differentiation;GO:0006935//chemotaxis;GO:0006464//cellular protein modification process;GO:0070555//response to interleukin-1;GO:0043062//extracellular structure organization;GO:0016477//cell migration;GO:0046689//response to mercury ion;GO:0022604//regulation of cell morphogenesis;GO:0007160//cell-matrix adhesion;GO:0002526//acute inflammatory response;GO:0006915//apoptotic process;GO:0034329//cell junction assembly;GO:0051345//positive regulation of hydrolase activity;GO:0000904//cell morphogenesis involved in differentiation;GO:0006935//chemotaxis;GO:0006464//cellular protein modification process;GO:0070555//response to interleukin-1;GO:0043062//extracellular structure organization;GO:0016477//cell migration gi|449083341|ref|NP_001263339.1|/0/fibronectin isoform d precursor [Mus musculus] 69076 1049 9.416666667 11.77666667 0.322642882 Up 0.474416112 Triap1 TP53 regulated inhibitor of apoptosis 1 K17968|1|1e-40|169|oas:101118643|TRIAP1/MDM35 family protein GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0004869//cysteine-type endopeptidase inhibitor activity "GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006915//apoptotic process" "gi|148687916|gb|EDL19863.1|/9.23538e-43/TP53 regulated inhibitor of apoptosis 1, partial [Mus musculus]" 65969 11339 0.626666667 0.103333333 -2.600392541 Down 0.474312686 Cubn cubilin (intrinsic factor-cobalamin receptor) K14616|1|0.0|7496|mmu:65969|cubilin GO:0005764//lysosome;GO:0032991//macromolecular complex;GO:0005903//brush border;GO:0044459;GO:0030139//endocytic vesicle;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0042802//identical protein binding GO:0017038//protein import;GO:0031667//response to nutrient levels;GO:0051260//protein homooligomerization;GO:0006897//endocytosis;GO:0044281//small molecule metabolic process gi|124487348|ref|NP_001074553.1|/0/cubilin precursor [Mus musculus] 66214 934 51.41 60.77 0.24131028 Up 0.474115236 Rgcc regulator of cell cycle K05012|1|2e-07|58.9|gfr:102042322|chloride channel 3/4/5 - - - - 13040 1357 16.15 19.67666667 0.284951676 Up 0.474030614 Ctss cathepsin S K01368|1|0.0|724|mmu:13040|cathepsin S [EC:3.4.22.27] GO:0000323//lytic vacuole;GO:0000323//lytic vacuole "GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0032870//cellular response to hormone stimulus;GO:0001894//tissue homeostasis;GO:0019233//sensory perception of pain;GO:0006955//immune response;GO:0019538//protein metabolic process;GO:0032870//cellular response to hormone stimulus;GO:0001894//tissue homeostasis;GO:0019233//sensory perception of pain;GO:0006955//immune response gi|74214026|dbj|BAE29430.1|/0/unnamed protein product [Mus musculus] 67885 812 24.22666667 29.03 0.260948653 Up 0.473945993 1500011K16Rik RIKEN cDNA 1500011K16 gene - - - - - 74485 3988 7.123333333 9.1 0.353314043 Up 0.473917786 Lrrc71 leucine rich repeat containing 71 K02978|1|1e-06|58.9|tru:101078248|small subunit ribosomal protein S27e;K10165|2|2e-06|58.2|ocu:100356594|nucleotide-binding oligomerization domain-containing protein 2 - - - gi|284055285|ref|NP_083247.1|/0/leucine-rich repeat-containing protein 71 [Mus musculus] 328417 6391 8.593333333 6.706666667 -0.357621959 Down 0.473889578 Parp4 "poly (ADP-ribose) polymerase family, member 4" K10798|1|0.0|2730|mmu:328417|poly [ADP-ribose] polymerase [EC:2.4.2.30] - - - gi|281485553|ref|NP_001139450.2|/0/poly [ADP-ribose] polymerase 4 [Mus musculus] 97908 492 0.126666667 0.663333333 2.388697107 Up 0.473729738 Hist1h3g "histone cluster 1, H3g" K11253|1|6e-72|271|cjc:100394108|histone H3 - - - gi|675650890|ref|XP_008992128.1|/3.8667e-71/PREDICTED: uncharacterized protein LOC100394108 [Callithrix jacchus] 18987 3249 0.463333333 1.146666667 1.307323682 Up 0.473692128 Pou2f2 "POU domain, class 2, transcription factor 2" "K09364|1|0.0|616|ecb:100069713|POU domain transcription factor, class 2" GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding "GO:0002381//immunoglobulin production involved in immunoglobulin mediated immune response;GO:0006351//transcription, DNA-templated;GO:0021700//developmental maturation;GO:0002381//immunoglobulin production involved in immunoglobulin mediated immune response;GO:0006351//transcription, DNA-templated;GO:0021700//developmental maturation;GO:0002381//immunoglobulin production involved in immunoglobulin mediated immune response;GO:0006351//transcription, DNA-templated;GO:0021700//developmental maturation" "gi|795398807|ref|XP_011942307.1|/0/PREDICTED: POU domain, class 2, transcription factor 2 isoform X1 [Cercocebus atys]" 66256 1183 32.54666667 38.73666667 0.251190019 Up 0.473353642 Ssr2 "signal sequence receptor, beta" K13250|1|3e-92|341|cge:100758563|translocon-associated protein subunit beta GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0019538//protein metabolic process;GO:0006613//cotranslational protein targeting to membrane;GO:0010467//gene expression "gi|148683321|gb|EDL15268.1|/9.8844e-108/signal sequence receptor, beta, isoform CRA_c, partial [Mus musculus]" 244853 3173 4.003333333 2.8 -0.515774918 Down 0.473193802 Nxpe4 "neurexophilin and PC-esterase domain family, member 4" "K02324|1|2e-29|134|sko:100367259|DNA polymerase epsilon subunit 1 [EC:2.7.7.7];K15010|2|7e-28|129|xma:102227992|homer;K07422|3|3e-12|77.0|bfo:BRAFLDRAFT_72966|cytochrome P450, family 2, subfamily U, polypeptide 1" - - - gi|71153005|sp|Q52KP5.1|NXPE4_MOUSE/0/RecName: Full=NXPE family member 4; AltName: Full=Protein FAM55D; Flags: Precursor 19720 4204 4.416666667 5.913333333 0.42101365 Up 0.47314679 Trim27 tripartite motif-containing 27 K12009|1|0.0|987|mmu:19720|tripartite motif-containing protein 27 [EC:2.3.2.27] GO:0031981//nuclear lumen;GO:0005635//nuclear envelope GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0019787//ubiquitin-like protein transferase activity GO:0006366//transcription from RNA polymerase II promoter;GO:0034766//negative regulation of ion transmembrane transport;GO:0050710//negative regulation of cytokine secretion;GO:0010629//negative regulation of gene expression;GO:0001818//negative regulation of cytokine production;GO:0001933//negative regulation of protein phosphorylation;GO:0051259//protein oligomerization;GO:0002250//adaptive immune response;GO:0032609//interferon-gamma production;GO:0032446//protein modification by small protein conjugation "gi|47122750|gb|AAH69924.1|/0/Tripartite motif-containing 27, partial [Mus musculus]" 93703 4684 1.11 1.98 0.834940754 Up 0.473043364 Pcdhgb6 "protocadherin gamma subfamily B, 6" K16496|1|0.0|1719|mmu:93703|protocadherin gamma subfamily B;K16495|5|0.0|1322|ssc:100516665|protocadherin gamma subfamily A GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|18087741|ref|NP_291056.1|/0/protocadherin gamma-B6 precursor [Mus musculus] 67111 2424 6.556666667 8.426666667 0.361999506 Up 0.472939938 Naaa N-acylethanolamine acid amidase K13720|1|0.0|711|mmu:67111|N-acylethanolamine-hydrolysing acid amidase [EC:3.5.1.-] GO:0000323//lytic vacuole;GO:0000323//lytic vacuole GO:0016787//hydrolase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0005515//protein binding GO:0044238//primary metabolic process;GO:0044238//primary metabolic process gi|255683420|ref|NP_001157159.1|/0/N-acylethanolamine-hydrolyzing acid amidase isoform 2 precursor [Mus musculus] 68195 1031 38.83666667 32.74333333 -0.246218182 Down 0.472892926 Rnaset2b ribonuclease T2B K01166|1|1e-158|561|mmu:68195|ribonuclease T2 [EC:3.1.27.1] GO:0044421;GO:0000323//lytic vacuole;GO:0044432 "GO:0016892//endoribonuclease activity, producing 3'-phosphomonoesters" GO:0016070//RNA metabolic process gi|21311883|ref|NP_080887.1|/8.45232e-158/ribonuclease T2B precursor [Mus musculus] 66440 794 23.54666667 28.20666667 0.260513343 Up 0.472723683 Cdc26 cell division cycle 26 K03359|1|3e-41|171|mmu:66440|anaphase-promoting complex subunit 12 GO:0000152//nuclear ubiquitin ligase complex - GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0007088//regulation of mitotic nuclear division gi|564351291|ref|XP_006238303.1|/1.64804e-42/PREDICTED: anaphase-promoting complex subunit CDC26 isoform X2 [Rattus norvegicus] 20610 2640.21 23.40666667 28.05 0.261081275 Up 0.472507428 Sumo3 small ubiquitin-like modifier 3 K12160|1|6e-54|215|mmu:20610|small ubiquitin-related modifier GO:0044451;GO:0044451;GO:0044451;GO:0044451;GO:0044451;GO:0044451 GO:0019787//ubiquitin-like protein transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0019787//ubiquitin-like protein transferase activity GO:0031398//positive regulation of protein ubiquitination;GO:0033365//protein localization to organelle;GO:0031398//positive regulation of protein ubiquitination;GO:0033365//protein localization to organelle;GO:0031398//positive regulation of protein ubiquitination;GO:0033365//protein localization to organelle;GO:0031398//positive regulation of protein ubiquitination;GO:0033365//protein localization to organelle;GO:0031398//positive regulation of protein ubiquitination;GO:0033365//protein localization to organelle;GO:0031398//positive regulation of protein ubiquitination;GO:0033365//protein localization to organelle gi|9910556|ref|NP_064313.1|/1.34673e-51/small ubiquitin-related modifier 3 isoform 1 precursor [Mus musculus] 69125 2035 15.88333333 19.32666667 0.283079119 Up 0.472385197 Cnot8 "CCR4-NOT transcription complex, subunit 8" K12581|1|1e-167|592|mmu:69125|CCR4-NOT transcription complex subunit 7/8 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0097159//organic cyclic compound binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0035194//posttranscriptional gene silencing by RNA;GO:0006351//transcription, DNA-templated;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0008283//cell proliferation" gi|13386186|ref|NP_081225.1|/1.15472e-166/CCR4-NOT transcription complex subunit 8 [Mus musculus] 12834 3729 37.01333333 31.02 -0.254846381 Down 0.472262966 Col6a2 "collagen, type VI, alpha 2" "K06238|1|0.0|1581|mmu:12834|collagen, type VI, alpha" GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix;GO:0032991//macromolecular complex - GO:0051291//protein heterooligomerization;GO:0009746 gi|22203747|ref|NP_666119.1|/0/collagen alpha-2(VI) chain precursor [Mus musculus] 13610 4484 9.01 7.063333333 -0.351177924 Down 0.472140735 S1pr3 sphingosine-1-phosphate receptor 3 K04290|1|0.0|717|mmu:13610|sphingosine 1-phosphate receptor 3 GO:0016021//integral component of membrane GO:0045125//bioactive lipid receptor activity;GO:0005488//binding GO:0006952//defense response;GO:0032611//interleukin-1 beta production;GO:0008283//cell proliferation;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0032502//developmental process;GO:0051480//regulation of cytosolic calcium ion concentration "gi|149045006|gb|EDL98092.1|/0/rCG44124, isoform CRA_a [Rattus norvegicus]" 68427 2212.7 16.11 19.53333333 0.27798167 Up 0.471990297 Slc39a13 "solute carrier family 39 (metal ion transporter), member 13" "K14719|1|2e-102|329|mmu:68427|solute carrier family 39 (zinc transporter), member 13" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0031228//intrinsic component of Golgi membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0042802//identical protein binding;GO:0046915//transition metal ion transmembrane transporter activity;GO:0042802//identical protein binding;GO:0046915//transition metal ion transmembrane transporter activity;GO:0042802//identical protein binding;GO:0046915//transition metal ion transmembrane transporter activity GO:0072503;GO:0009888//tissue development;GO:0006829//zinc II ion transport;GO:0009888//tissue development;GO:0006829//zinc II ion transport;GO:0072503;GO:0072503;GO:0009888//tissue development;GO:0006829//zinc II ion transport gi|595577337|ref|NP_001277694.1|/1.04806e-177/zinc transporter ZIP13 isoform a precursor [Mus musculus] 654440 2126.93 7.81 9.853333333 0.335289315 Up 0.471933882 A430046D13Rik Riken cDNA A430046D13 gene K09228|1|7e-10|68.6|cge:100764777|KRAB domain-containing zinc finger protein;K10591|2|2e-08|63.5|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] - - - - 19172 949 100.38 117.5333333 0.227598123 Up 0.471548385 Psmb4 "proteasome (prosome, macropain) subunit, beta type 4" K02736|1|1e-151|537|mmu:19172|20S proteasome subunit beta 7 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity;GO:0008289//lipid binding GO:0002437//inflammatory response to antigenic stimulus;GO:0006508//proteolysis gi|254540082|ref|NP_032971.2|/1.13449e-150/proteasome subunit beta type-4 precursor [Mus musculus] 226777 2857 16.34 13.33666667 -0.293009856 Down 0.47152958 C130074G19Rik RIKEN cDNA C130074G19 gene - GO:0031224//intrinsic component of membrane - - gi|30520091|ref|NP_848807.1|/2.33125e-62/uncharacterized protein C1orf115 homolog [Mus musculus] 15170 2219 2.54 3.686666667 0.537488483 Up 0.471444958 Ptpn6 "protein tyrosine phosphatase, non-receptor type 6" K05697|1|0.0|1186|mmu:15170|tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48] GO:0043231//intracellular membrane-bounded organelle;GO:0042101//T cell receptor complex;GO:0043231//intracellular membrane-bounded organelle;GO:0042101//T cell receptor complex GO:0005102//receptor binding;GO:0004725//protein tyrosine phosphatase activity;GO:0019904//protein domain specific binding;GO:0019900//kinase binding;GO:0045309//protein phosphorylated amino acid binding;GO:0005102//receptor binding;GO:0004725//protein tyrosine phosphatase activity;GO:0019904//protein domain specific binding;GO:0019900//kinase binding;GO:0045309//protein phosphorylated amino acid binding GO:1901990//regulation of mitotic cell cycle phase transition;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0030183//B cell differentiation;GO:0001933//negative regulation of protein phosphorylation;GO:0009967//positive regulation of signal transduction;GO:0050852//T cell receptor signaling pathway;GO:0043405//regulation of MAP kinase activity;GO:0006950//response to stress;GO:0006470//protein dephosphorylation;GO:0001909//leukocyte mediated cytotoxicity;GO:0042098//T cell proliferation;GO:1901990//regulation of mitotic cell cycle phase transition;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0030183//B cell differentiation;GO:0001933//negative regulation of protein phosphorylation;GO:0009967//positive regulation of signal transduction;GO:0050852//T cell receptor signaling pathway;GO:0043405//regulation of MAP kinase activity;GO:0006950//response to stress;GO:0006470//protein dephosphorylation;GO:0001909//leukocyte mediated cytotoxicity;GO:0042098//T cell proliferation gi|118130771|ref|NP_038573.2|/0/tyrosine-protein phosphatase non-receptor type 6 isoform a [Mus musculus] 106952 5277.81 22.74666667 18.88333333 -0.268541691 Down 0.471444958 Arap3 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3" "K12490|1|0.0|2537|mmu:106952|Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3" - - - gi|18700711|gb|AAL78678.1|AF469622_1/0/dual-specificity Rho- and Arf-GTPase activating protein 1 [Mus musculus] 114676 1545 1.45 2.393333333 0.722968443 Up 0.471369739 4930519F09Rik pyruvate dehydrogenase E1 alpha 1 pseudogene K00161|1|3e-115|348|rno:29554|pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1] GO:0043234//protein complex;GO:0005759//mitochondrial matrix GO:0004738//pyruvate dehydrogenase activity GO:0006007//glucose catabolic process;GO:0006085//acetyl-CoA biosynthetic process;GO:0009060//aerobic respiration "gi|6679261|ref|NP_032836.1|/2.61913e-114/pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial precursor [Mus musculus]" 54375 4900.06 9.566666667 7.536666667 -0.344089745 Down 0.471369739 Azin1 antizyme inhibitor 1 K01581|1|2e-122|444|xla:379859|ornithine decarboxylase [EC:4.1.1.17] - GO:0008047//enzyme activator activity;GO:0004857//enzyme inhibitor activity;GO:0008047//enzyme activator activity;GO:0004857//enzyme inhibitor activity;GO:0008047//enzyme activator activity;GO:0004857//enzyme inhibitor activity;GO:0008047//enzyme activator activity;GO:0004857//enzyme inhibitor activity GO:0006595//polyamine metabolic process;GO:0044093;GO:0044092//negative regulation of molecular function;GO:0006595//polyamine metabolic process;GO:0044093;GO:0044092//negative regulation of molecular function;GO:0006595//polyamine metabolic process;GO:0044093;GO:0044092//negative regulation of molecular function;GO:0006595//polyamine metabolic process;GO:0044093;GO:0044092//negative regulation of molecular function gi|9055298|ref|NP_061215.1|/0/antizyme inhibitor 1 isoform 1 [Mus musculus] 69742 1298 31.04 36.85666667 0.247797041 Up 0.47109707 Tm2d2 TM2 domain containing 2 K09488|1|1e-43|179|tsp:Tsp_13481|TNF receptor-associated protein 1;K03511|2|1e-10|70.5|tsp:Tsp_01714|DNA polymerase kappa [EC:2.7.7.7] GO:0031224//intrinsic component of membrane - - gi|12846070|dbj|BAB27019.1|/1.8098e-113/unnamed protein product [Mus musculus] 18682 2391 13.39 16.37 0.289898361 Up 0.470993644 Phkg1 phosphorylase kinase gamma 1 K00871|1|0.0|764|mmu:18682|phosphorylase kinase gamma subunit [EC:2.7.11.19] GO:0043234//protein complex GO:0032550;GO:0005515//protein binding;GO:0004683//calmodulin-dependent protein kinase activity GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0005977//glycogen metabolic process "gi|6755054|ref|NP_035209.1|/0/phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform [Mus musculus]" 117171 1116 11.42 14.1 0.304132512 Up 0.470909023 1110038F14Rik RIKEN cDNA 1110038F14 gene K01443|1|6e-22|107|amj:102573560|N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25] - - - gi|123784286|sp|Q3U6N9.1|CH033_MOUSE/1.78349e-79/RecName: Full=UPF0488 protein C8orf33 homolog 211429 3859 0.456666667 1.126666667 1.302847353 Up 0.470843206 Pla2g4b "phospholipase A2, group IVB (cytosolic)" K16342|1|0.0|1496|mmu:211429|cytosolic phospholipase A2 [EC:3.1.1.4] - GO:0004620//phospholipase activity - gi|167900427|ref|NP_663353.3|/0/cytosolic phospholipase A2 beta [Mus musculus] 12892 3186 13.23333333 16.2 0.291817306 Up 0.470777389 Cpox coproporphyrinogen oxidase K00228|1|0.0|819|mmu:12892|coproporphyrinogen III oxidase [EC:1.3.3.3] GO:0019866//organelle inner membrane;GO:0005740//mitochondrial envelope GO:0042802//identical protein binding GO:0009636//response to toxic substance;GO:0010038//response to metal ion;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0010033//response to organic substance "gi|161484660|ref|NP_031783.2|/0/oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial precursor [Mus musculus]" 98170 3543 6.42 8.253333333 0.362403611 Up 0.470655158 Tmem132a transmembrane protein 132A K17599|1|0.0|1768|mmu:98170|transmembrane protein 132 GO:0012505//endomembrane system;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0007417//central nervous system development;GO:0012501//programmed cell death gi|50510999|dbj|BAD32485.1|/0/mKIAA1583 protein [Mus musculus] 56642 1100 0.723333333 0.166666667 -2.117695043 Down 0.470655158 Ankrd2 ankyrin repeat domain 2 (stretch responsive muscle) K15503|1|6e-24|114|dre:561373|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B GO:0030017//sarcomere GO:0008092//cytoskeletal protein binding GO:0007519//skeletal muscle tissue development gi|19912278|dbj|BAB88557.1|/1.8757e-174/ankyrin-repeat PEST sequence and proline-rich region protein [Mus musculus] 57267 2124 44.10666667 52.22 0.243605724 Up 0.470598744 Apba3 "amyloid beta (A4) precursor protein-binding, family A, member 3" K04531|1|7e-127|457|lcm:102351416|amyloid beta A4 precursor protein-binding family A member 1 GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0030234//enzyme regulator activity GO:0043009//chordate embryonic development;GO:0045184//establishment of protein localization;GO:0010467//gene expression;GO:0007267//cell-cell signaling;GO:0044092//negative regulation of molecular function gi|9055382|ref|NP_061228.1|/0/amyloid beta A4 precursor protein-binding family A member 3 [Mus musculus] 21957 1024 0.103333333 0.616666667 2.57718515 Up 0.470523525 Tnnt3 "troponin T3, skeletal, fast" "K12046|1|7e-75|283|cjc:100394172|troponin T, fast skeletal muscle" - - - "gi|568952754|ref|XP_006508605.1|/3.70165e-94/PREDICTED: troponin T, fast skeletal muscle isoform X1 [Mus musculus]" 66617 1217 11.19333333 8.936666667 -0.324831011 Down 0.470448306 Ntmt1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 K16219|1|5e-127|456|mmu:66617|protein N-terminal methyltransferase [EC:2.1.1.244] GO:0031981//nuclear lumen GO:0008168//methyltransferase activity GO:0035568//N-terminal peptidyl-proline methylation;GO:0000226//microtubule cytoskeleton organization;GO:0035570//N-terminal peptidyl-serine methylation;GO:0018011//N-terminal peptidyl-alanine methylation gi|564340256|ref|XP_006233981.1|/8.71009e-131/PREDICTED: N-terminal Xaa-Pro-Lys N-methyltransferase 1 isoform X2 [Rattus norvegicus] 66395 16276.94 27.04666667 22.6 -0.259128029 Down 0.470429501 Ahnak AHNAK nucleoprotein (desmoyokin) K19326|1|6e-46|191|api:100167295|nesprin-1 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0048731//system development gi|795168017|ref|XP_011798092.1|/3.36067e-93/PREDICTED: uncharacterized protein LOC105512277 [Colobus angolensis palliatus] 140497 1139 0.703333333 1.44 1.033788313 Up 0.470410696 AF251705 CD300C molecule 2 K06719|1|2e-121|438|mmu:140497|CD300A/C/E/H antigen GO:0031224//intrinsic component of membrane - GO:0050663//cytokine secretion "gi|148702509|gb|EDL34456.1|/7.09317e-132/mCG146304, isoform CRA_b, partial [Mus musculus]" 68312 1339 30.36 36.06 0.248227606 Up 0.470344879 Gstm7 "glutathione S-transferase, mu 7" K00799|1|2e-126|454|mmu:68312|glutathione S-transferase [EC:2.5.1.18] - - - - 14077 669 4146.83 4832.74 0.220832475 Up 0.47030727 Fabp3 "fatty acid binding protein 3, muscle and heart" "K08752|1|7e-70|265|mmu:14077|fatty acid-binding protein 3, muscle and heart" GO:0005783//endoplasmic reticulum GO:0015245//fatty acid transporter activity;GO:0005515//protein binding;GO:0036041//long-chain fatty acid binding GO:0033993//response to lipid;GO:0015908//fatty acid transport;GO:0009062//fatty acid catabolic process;GO:0043434//response to peptide hormone;GO:0022611//dormancy process;GO:0046165 "gi|6753810|ref|NP_034304.1|/5.50649e-69/fatty acid-binding protein, heart [Mus musculus]" 67260 3668 5.293333333 6.913333333 0.385204982 Up 0.47026966 Cers4 ceramide synthase 4 K04710|1|0.0|693|mmu:67260|ceramide synthetase [EC:2.3.1.24] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0016410//N-acyltransferase activity "GO:0006796//phosphate-containing compound metabolic process;GO:0006672//ceramide metabolic process;GO:0006351//transcription, DNA-templated" gi|165972325|ref|NP_080334.3|/0/ceramide synthase 4 [Mus musculus] 56434 1747 89.18666667 104.4266667 0.22759022 Up 0.470203844 Tspan3 tetraspanin 3 K17293|1|4e-130|467|mmu:56434|tetraspanin-3 - - - - 668303 6918 6.24 4.71 -0.405818969 Down 0.470091015 Kif26a kinesin family member 26A K10404|1|0.0|3150|mmu:668303|kinesin family member 26 - - - - 433520 3734 2.526666667 3.67 0.538544715 Up 0.470081613 Gm14403 predicted gene 14403 K09228|1|7e-170|441|mmu:100043915|KRAB domain-containing zinc finger protein - - - - 330192 2512 12.97 15.89 0.292940645 Up 0.469808944 Vps37b vacuolar protein sorting 37B K12185|1|7e-118|427|mmu:330192|ESCRT-I complex subunit VPS37 GO:0005768//endosome;GO:0031090//organelle membrane GO:0005488//binding GO:0044765//single-organism transport;GO:0044763;GO:0045184//establishment of protein localization "gi|148687661|gb|EDL19608.1|/8.85314e-119/vacuolar protein sorting 37B (yeast), isoform CRA_a, partial [Mus musculus]" 11689 2827 4.886666667 6.446666667 0.399702691 Up 0.469733724 Alox5 arachidonate 5-lipoxygenase K00461|1|0.0|1356|mmu:11689|arachidonate 5-lipoxygenase [EC:1.13.11.34] GO:0043005//neuron projection;GO:0034399//nuclear periphery;GO:0044444//cytoplasmic part;GO:0005635//nuclear envelope;GO:0005886//plasma membrane "GO:0046914//transition metal ion binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" GO:0007600//sensory perception;GO:0002538;GO:0031667//response to nutrient levels;GO:0006690//icosanoid metabolic process;GO:0019229//regulation of vasoconstriction;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0001676//long-chain fatty acid metabolic process gi|62526037|ref|NP_033792.1|/0/arachidonate 5-lipoxygenase [Mus musculus] 54598 4761 4.62 3.333333333 -0.470927257 Down 0.469696115 Calcrl calcitonin receptor-like K04577|1|0.0|889|mmu:54598|calcitonin receptor-like GO:0016021//integral component of membrane;GO:0000323//lytic vacuole GO:0022892//substrate-specific transporter activity;GO:0008528//G-protein coupled peptide receptor activity;GO:0005488//binding GO:0009744//response to sucrose;GO:0006898//receptor-mediated endocytosis;GO:0006936//muscle contraction;GO:0008284//positive regulation of cell proliferation;GO:0006171//cAMP biosynthetic process;GO:0070838//divalent metal ion transport;GO:0045184//establishment of protein localization;GO:0006954//inflammatory response;GO:0044767//single-organism developmental process;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway gi|213385308|ref|NP_061252.2|/0/calcitonin gene-related peptide type 1 receptor precursor [Mus musculus] 77045 3809 4.61 6.13 0.411120323 Up 0.469338824 Bcl7a B cell CLL/lymphoma 7A - - - "GO:0006351//transcription, DNA-templated" "gi|148687692|gb|EDL19639.1|/9.63928e-91/B-cell CLL/lymphoma 7A, isoform CRA_a, partial [Mus musculus]" 238871 7049 4.793333333 6.34 0.40345357 Up 0.469066155 Pde4d "phosphodiesterase 4D, cAMP specific" K13293|1|0.0|1454|mmu:238871|cAMP-specific phosphodiesterase 4 [EC:3.1.4.53] GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0043292//contractile fiber "GO:0044389//ubiquitin-like protein ligase binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0019904//protein domain specific binding;GO:0030551//cyclic nucleotide binding;GO:0043169//cation binding" GO:0007186//G-protein coupled receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0007611//learning or memory;GO:0040007//growth;GO:0006461//protein complex assembly;GO:0001885//endothelial cell development;GO:0006936//muscle contraction;GO:0046058//cAMP metabolic process;GO:0030595//leukocyte chemotaxis "gi|23510241|ref|NP_035186.1|/0/cAMP-specific 3',5'-cyclic phosphodiesterase 4D [Mus musculus]" 26912 2040.83 5.5 7.163333333 0.381199458 Up 0.468859303 Gcat glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase) K00639|1|0.0|734|mmu:26912|glycine C-acetyltransferase [EC:2.3.1.29] GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0043168//anion binding;GO:0016453;GO:0043168//anion binding;GO:0016453 GO:0008152//metabolic process;GO:0008152//metabolic process "gi|240120117|ref|NP_038875.3|/0/2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial isoform a [Mus musculus]" 230861 6156.95 12.31 9.91 -0.312873799 Down 0.46825755 Eif4g3 "eukaryotic translation initiation factor 4 gamma, 3" K03260|1|0.0|2650|mmu:230861|translation initiation factor 4G - "GO:0008135//translation factor activity, RNA binding" GO:0006412//translation;GO:0007127//meiosis I;GO:0048232//male gamete generation gi|568931058|ref|XP_006538842.1|/0/PREDICTED: eukaryotic translation initiation factor 4 gamma 3 isoform X9 [Mus musculus] 13592 5527.14 1.843333333 1.013333333 -0.863208157 Down 0.468135319 Ebf2 early B cell factor 2 K09103|1|0.0|1046|mmu:13592|early B-cell factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding "GO:0006351//transcription, DNA-templated;GO:0032502//developmental process;GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|6753704|ref|NP_034225.1|/0/transcription factor COE2 [Mus musculus] 50880 2207 11.12333333 13.7 0.300586707 Up 0.468013088 Scly selenocysteine lyase K01763|1|0.0|861|mmu:50880|selenocysteine lyase [EC:4.4.1.16] GO:0044424 GO:0016846//carbon-sulfur lyase activity;GO:0043168//anion binding - gi|568909391|ref|XP_006529807.1|/0/PREDICTED: selenocysteine lyase isoform X2 [Mus musculus] 380967 1535.46 8.776666667 10.97 0.321818505 Up 0.467646395 Tmem106c transmembrane protein 106C - GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle - - "gi|148672267|gb|EDL04214.1|/6.22436e-138/transmembrane protein 106C, isoform CRA_a [Mus musculus]" 56490 3037.41 28.15333333 33.44333333 0.248412903 Up 0.467552371 Zbtb20 zinc finger and BTB domain containing 20 K10501|1|0.0|1408|mmu:56490|zinc finger and BTB domain-containing protein 20 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding" "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|6063139|gb|AAF03152.1|AF185576_1/0/BTB/POZ domain zinc finger factor HOF-L [Mus musculus] 68794 8951.8 80.61333333 68.51333333 -0.234633701 Down 0.467420738 Flnc "filamin C, gamma" K04437|1|0.0|5376|rno:362332|filamin - - - - 102595 5127 5.38 7.02 0.383864858 Up 0.467364324 Plekho2 "pleckstrin homology domain containing, family O member 2" - - GO:0008289//lipid binding - gi|24025665|ref|NP_694759.1|/0/pleckstrin homology domain-containing family O member 2 [Mus musculus] 226407 4251 15.48666667 12.68 -0.288471908 Down 0.467317312 Rab3gap1 RAB3 GTPase activating protein subunit 1 K18270|1|0.0|1904|mmu:226407|Rab3 GTPase-activating protein catalytic subunit - - - - 66050 795 11.05 13.60333333 0.29991384 Up 0.467279702 0610009B22Rik RIKEN cDNA 0610009B22 gene K20301|1|2e-78|294|mmu:66050|trafficking protein particle complex subunit 2 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005515//protein binding "GO:0048731//system development;GO:0016482//cytosolic transport;GO:0006351//transcription, DNA-templated" gi|13384686|ref|NP_079595.1|/1.20812e-77/uncharacterized protein LOC66050 [Mus musculus] 102115 1455 27.27 32.52 0.254012557 Up 0.4672703 Dohh deoxyhypusine hydroxylase/monooxygenase K06072|1|7e-159|562|mmu:102115|deoxyhypusine monooxygenase [EC:1.14.99.29] - GO:0043169//cation binding;GO:0004497//monooxygenase activity GO:0044710;GO:0018205//peptidyl-lysine modification gi|26327755|dbj|BAC25064.1|/4.78192e-173/unnamed protein product [Mus musculus] 24116 2162 9.773333333 12.14 0.312845819 Up 0.467204483 Nelfa "negative elongation factor complex member A, Whsc2" K15179|1|0.0|771|mmu:24116|negative elongation factor A GO:0008023//transcription elongation factor complex GO:0005488//binding GO:0044764;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0032502//developmental process;GO:0010557//positive regulation of macromolecule biosynthetic process gi|33859652|ref|NP_036044.1|/0/negative elongation factor A [Mus musculus] 16515 4437 17.55333333 21.14 0.268230356 Up 0.467091654 Kcnj12 "potassium inwardly-rectifying channel, subfamily J, member 12" K05005|1|0.0|986|cge:100773954|potassium inwardly-rectifying channel subfamily J member 12 GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0042383//sarcolemma;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0042383//sarcolemma GO:0005249//voltage-gated potassium channel activity;GO:0019904//protein domain specific binding;GO:0005249//voltage-gated potassium channel activity;GO:0019904//protein domain specific binding GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|390013285|ref|NP_034733.4|/0/ATP-sensitive inward rectifier potassium channel 12 isoform 1 [Mus musculus] 69601 6003.53 32.89666667 27.67333333 -0.249444976 Down 0.467044643 Dab2ip disabled 2 interacting protein K19901|1|0.0|1937|mmu:69601|disabled homolog 2-interacting protein GO:0044464;GO:0016020//membrane;GO:0044464;GO:0016020//membrane "GO:0008289//lipid binding;GO:0008047//enzyme activator activity;GO:0060090//binding, bridging;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0008289//lipid binding;GO:0008047//enzyme activator activity;GO:0060090//binding, bridging;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0032813//tumor necrosis factor receptor superfamily binding" GO:0006915//apoptotic process;GO:0034976//response to endoplasmic reticulum stress;GO:0035411//catenin import into nucleus;GO:0016049//cell growth;GO:0034260//negative regulation of GTPase activity;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0001837//epithelial to mesenchymal transition;GO:0007254//JNK cascade;GO:0007265//Ras protein signal transduction;GO:0006469//negative regulation of protein kinase activity;GO:0070849//response to epidermal growth factor;GO:0030178//negative regulation of Wnt signaling pathway;GO:0010594//regulation of endothelial cell migration;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0000187//activation of MAPK activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0030163//protein catabolic process;GO:0034612//response to tumor necrosis factor;GO:0006915//apoptotic process;GO:0034976//response to endoplasmic reticulum stress;GO:0035411//catenin import into nucleus;GO:0016049//cell growth;GO:0034260//negative regulation of GTPase activity;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0001837//epithelial to mesenchymal transition;GO:0007254//JNK cascade;GO:0007265//Ras protein signal transduction;GO:0006469//negative regulation of protein kinase activity;GO:0070849//response to epidermal growth factor;GO:0030178//negative regulation of Wnt signaling pathway;GO:0010594//regulation of endothelial cell migration;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0000187//activation of MAPK activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0030163//protein catabolic process;GO:0034612//response to tumor necrosis factor gi|594591605|ref|NP_001277569.1|/0/disabled homolog 2-interacting protein isoform 5 [Mus musculus] 105940408 1236 5.736666667 7.436666667 0.374443416 Up 0.466960021 Synj2bp-cox16 Synj2bp-cox16 readthrough K20057|1|2e-75|285|mmu:105940408|synaptojanin-2-binding protein GO:0031306//intrinsic component of mitochondrial outer membrane GO:0005515//protein binding GO:0007265//Ras protein signal transduction;GO:0048311//mitochondrion distribution;GO:0006897//endocytosis;GO:0006886//intracellular protein transport gi|836468835|ref|NP_001296777.1|/1.5835e-74/Synj2bp-cox16 protein isoform 2 [Mus musculus] 100041294 710 0.166666667 0.713333333 2.097610797 Up 0.466941216 Supt4b suppressor of Ty 4B K15171|1|3e-63|243|mmu:100041294|transcription elongation factor SPT4 - - - - 12972 2558 2.636666667 3.79 0.523482654 Up 0.466706157 Cryz "crystallin, zeta" K00344|1|1e-178|629|mmu:12972|NADPH2:quinone reductase [EC:1.6.5.5] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0003729//mRNA binding;GO:0043168//anion binding;GO:0046914//transition metal ion binding;GO:0000166//nucleotide binding;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor" GO:0044710;GO:0006805//xenobiotic metabolic process;GO:0051260//protein homooligomerization "gi|148679941|gb|EDL11888.1|/1.327e-178/crystallin, zeta, isoform CRA_b, partial [Mus musculus]" 69367 3603 11.04333333 13.57333333 0.297599358 Up 0.466668547 Glrx2 glutaredoxin 2 (thioltransferase) K03676|1|1e-67|261|mmu:69367|glutaredoxin 3 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0043169//cation binding;GO:0015036//disulfide oxidoreductase activity;GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding;GO:0015036//disulfide oxidoreductase activity;GO:0051536//iron-sulfur cluster binding;GO:0051536//iron-sulfur cluster binding;GO:0030611//arsenate reductase activity;GO:0043169//cation binding;GO:0015037//peptide disulfide oxidoreductase activity;GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups;GO:0043169//cation binding;GO:0015036//disulfide oxidoreductase activity;GO:0051536//iron-sulfur cluster binding" "GO:0051234//establishment of localization;GO:0019725//cellular homeostasis;GO:0000302//response to reactive oxygen species;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization;GO:0019725//cellular homeostasis;GO:0000302//response to reactive oxygen species;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization;GO:0006351//transcription, DNA-templated;GO:0012501//programmed cell death;GO:0044267//cellular protein metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006259//DNA metabolic process;GO:0000302//response to reactive oxygen species;GO:0019725//cellular homeostasis;GO:0006790//sulfur compound metabolic process;GO:0007165//signal transduction;GO:0009628//response to abiotic stimulus;GO:0048869//cellular developmental process;GO:0051234//establishment of localization;GO:0019725//cellular homeostasis;GO:0000302//response to reactive oxygen species;GO:0006091//generation of precursor metabolites and energy" "gi|41107595|gb|AAH65387.1|/2.5661e-70/Glrx2 protein, partial [Mus musculus]" 11865 2921 4.78 6.303333333 0.399104339 Up 0.466480499 Arntl aryl hydrocarbon receptor nuclear translocator-like K02296|1|0.0|1200|mmu:11865|aryl hydrocarbon receptor nuclear translocator-like protein 1 GO:0043234//protein complex;GO:0044451;GO:0043234//protein complex;GO:0044451 "GO:0031072//heat shock protein binding;GO:0003676//nucleic acid binding;GO:0060089;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0005102//receptor binding;GO:0046983//protein dimerization activity;GO:0008134//transcription factor binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0031072//heat shock protein binding;GO:0003676//nucleic acid binding;GO:0060089;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0005102//receptor binding;GO:0046983//protein dimerization activity;GO:0008134//transcription factor binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" GO:0009894;GO:0007623//circadian rhythm;GO:0007154//cell communication;GO:0006366//transcription from RNA polymerase II promoter;GO:0009894;GO:0007623//circadian rhythm;GO:0007154//cell communication;GO:0006366//transcription from RNA polymerase II promoter gi|537206173|gb|ERE79929.1|/0/aryl hydrocarbon receptor nuclear translocator-like protein 1 [Cricetulus griseus] 13400 2734.46 274.89 319.3766667 0.21640449 Up 0.466433488 Dmpk dystrophia myotonica-protein kinase K08788|1|0.0|974|rno:308405|dystrophia myotonica-protein kinase [EC:2.7.11.1] GO:0005789//endoplasmic reticulum membrane;GO:0005635//nuclear envelope;GO:0031306//intrinsic component of mitochondrial outer membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005635//nuclear envelope;GO:0031306//intrinsic component of mitochondrial outer membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005635//nuclear envelope;GO:0031306//intrinsic component of mitochondrial outer membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005635//nuclear envelope;GO:0031306//intrinsic component of mitochondrial outer membrane GO:0032550;GO:0004672//protein kinase activity;GO:0043169//cation binding;GO:0019888//protein phosphatase regulator activity;GO:0032550;GO:0004672//protein kinase activity;GO:0043169//cation binding;GO:0019888//protein phosphatase regulator activity;GO:0032550;GO:0004672//protein kinase activity;GO:0043169//cation binding;GO:0019888//protein phosphatase regulator activity;GO:0032550;GO:0004672//protein kinase activity;GO:0043169//cation binding;GO:0019888//protein phosphatase regulator activity GO:0014852;GO:0006796//phosphate-containing compound metabolic process;GO:0014902//myotube differentiation;GO:0050807//regulation of synapse organization;GO:0006997//nucleus organization;GO:0006464//cellular protein modification process;GO:0019722//calcium-mediated signaling;GO:0006814//sodium ion transport;GO:0006875//cellular metal ion homeostasis;GO:0014852;GO:0006796//phosphate-containing compound metabolic process;GO:0014902//myotube differentiation;GO:0050807//regulation of synapse organization;GO:0006997//nucleus organization;GO:0006464//cellular protein modification process;GO:0019722//calcium-mediated signaling;GO:0006814//sodium ion transport;GO:0006875//cellular metal ion homeostasis;GO:0014852;GO:0006796//phosphate-containing compound metabolic process;GO:0014902//myotube differentiation;GO:0050807//regulation of synapse organization;GO:0006997//nucleus organization;GO:0006464//cellular protein modification process;GO:0019722//calcium-mediated signaling;GO:0006814//sodium ion transport;GO:0006875//cellular metal ion homeostasis;GO:0014852;GO:0006796//phosphate-containing compound metabolic process;GO:0014902//myotube differentiation;GO:0050807//regulation of synapse organization;GO:0006997//nucleus organization;GO:0006464//cellular protein modification process;GO:0019722//calcium-mediated signaling;GO:0006814//sodium ion transport;GO:0006875//cellular metal ion homeostasis gi|14192945|ref|NP_115794.1|/0/myotonin-protein kinase isoform 1 [Mus musculus] 11993 1650.65 38.51 45.41333333 0.237882811 Up 0.46624544 Aup1 ancient ubiquitous protein 1 K19716|1|1e-163|525|cge:100760920|ancient ubiquitous protein 1 GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen GO:0016740//transferase activity;GO:0016740//transferase activity;GO:0016740//transferase activity - gi|913511184|ref|XP_005364744.2|/7.78665e-173/PREDICTED: ancient ubiquitous protein 1 [Microtus ochrogaster] 76797 865 0.873333333 0.28 -1.641105579 Down 0.465916356 2410137M14Rik RIKEN cDNA 2410137M14 gene "K06751|1|1e-43|179|rno:309584|major histocompatibility complex, class I" GO:0044425 - GO:0019882//antigen processing and presentation gi|21746171|ref|NP_084023.1|/3.84985e-83/uncharacterized protein LOC76797 [Mus musculus] 24053 3515 64.4 75.35666667 0.226674462 Up 0.465577871 Sgcg "sarcoglycan, gamma (dystrophin-associated glycoprotein)" K12564|1|5e-144|514|mmu:24053|gamma-sarcoglycan GO:0043232;GO:0016011//dystroglycan complex;GO:0016021//integral component of membrane - GO:0006996//organelle organization gi|6755488|ref|NP_036022.1|/4.44275e-143/gamma-sarcoglycan [Mus musculus] 66058 1064 7.783333333 9.816666667 0.334845084 Up 0.465371018 Tmem176a transmembrane protein 176A - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0045596//negative regulation of cell differentiation;GO:0045596//negative regulation of cell differentiation gi|148298742|ref|NP_079602.4|/3.62615e-127/transmembrane protein 176A [Mus musculus] 68490 2179 5 6.55 0.389566812 Up 0.465333409 Zfp579 zinc finger protein 579 K09230|1|1e-18|97.4|nle:100589400|SCAN domain-containing zinc finger protein - GO:0005488//binding - gi|66955864|ref|NP_081017.1|/0/zinc finger protein 579 [Mus musculus] 79233 4144 5.07 3.726666667 -0.444099965 Down 0.465295799 Zfp319 zinc finger protein 319 K09228|1|2e-109|400|myb:102259112|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|40254353|ref|NP_077787.3|/0/zinc finger protein 319 [Mus musculus] 13002 4350.22 24.69666667 20.68333333 -0.255847623 Down 0.465126556 Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 K09525|1|2e-89|334|bacu:103012333|DnaJ homolog subfamily C member 5 - - - - 11421 4847.19 43.74666667 37.11333333 -0.237235511 Down 0.465032532 Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 K01283|1|0.0|2644|mmu:11421|peptidyl-dipeptidase A [EC:3.4.15.1] GO:0043231//intracellular membrane-bounded organelle;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0043231//intracellular membrane-bounded organelle;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0043231//intracellular membrane-bounded organelle;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0044421 GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0033218//amide binding;GO:0008092//cytoskeletal protein binding;GO:0043168//anion binding;GO:0001664//G-protein coupled receptor binding;GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0033218//amide binding;GO:0008092//cytoskeletal protein binding;GO:0043168//anion binding;GO:0001664//G-protein coupled receptor binding;GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0033218//amide binding;GO:0008092//cytoskeletal protein binding;GO:0043168//anion binding;GO:0001664//G-protein coupled receptor binding GO:0001525//angiogenesis;GO:0030324//lung development;GO:0014909//smooth muscle cell migration;GO:0015909//long-chain fatty acid transport;GO:0003073//regulation of systemic arterial blood pressure;GO:0006518//peptide metabolic process;GO:0010720//positive regulation of cell development;GO:0006915//apoptotic process;GO:0002444;GO:0009056//catabolic process;GO:0009887//organ morphogenesis;GO:0048232//male gamete generation;GO:0006954//inflammatory response;GO:0007600//sensory perception;GO:0009991//response to extracellular stimulus;GO:0007631//feeding behavior;GO:0002237//response to molecule of bacterial origin;GO:0050880//regulation of blood vessel size;GO:0003015//heart process;GO:0019538//protein metabolic process;GO:0001525//angiogenesis;GO:0030324//lung development;GO:0014909//smooth muscle cell migration;GO:0015909//long-chain fatty acid transport;GO:0003073//regulation of systemic arterial blood pressure;GO:0006518//peptide metabolic process;GO:0010720//positive regulation of cell development;GO:0006915//apoptotic process;GO:0002444;GO:0009056//catabolic process;GO:0009887//organ morphogenesis;GO:0048232//male gamete generation;GO:0006954//inflammatory response;GO:0007600//sensory perception;GO:0009991//response to extracellular stimulus;GO:0007631//feeding behavior;GO:0002237//response to molecule of bacterial origin;GO:0050880//regulation of blood vessel size;GO:0003015//heart process;GO:0019538//protein metabolic process;GO:0001525//angiogenesis;GO:0030324//lung development;GO:0014909//smooth muscle cell migration;GO:0015909//long-chain fatty acid transport;GO:0003073//regulation of systemic arterial blood pressure;GO:0006518//peptide metabolic process;GO:0010720//positive regulation of cell development;GO:0006915//apoptotic process;GO:0002444;GO:0009056//catabolic process;GO:0009887//organ morphogenesis;GO:0048232//male gamete generation;GO:0006954//inflammatory response;GO:0007600//sensory perception;GO:0009991//response to extracellular stimulus;GO:0007631//feeding behavior;GO:0002237//response to molecule of bacterial origin;GO:0050880//regulation of blood vessel size;GO:0003015//heart process;GO:0019538//protein metabolic process gi|46559389|ref|NP_997507.1|/0/angiotensin-converting enzyme isoform 1 precursor [Mus musculus] 58245 2877 7.183333333 9.093333333 0.340155775 Up 0.464966716 Gpr180 G protein-coupled receptor 180 - GO:0031224//intrinsic component of membrane - GO:0007166//cell surface receptor signaling pathway;GO:0010033//response to organic substance gi|31560316|ref|NP_067409.2|/0/integral membrane protein GPR180 precursor [Mus musculus] 102632488 710 0.253333333 0.836666667 1.723616041 Up 0.464637632 Gm29508 predicted gene 29508 - - - - "gi|148686895|gb|EDL18842.1|/2.48043e-33/mCG144677, partial [Mus musculus]" 21968 2287.24 59.88333333 70.37333333 0.23287432 Up 0.464600023 Tom1 target of myb1 trafficking protein K12404|1|1e-27|127|mze:101485576|ADP-ribosylation factor-binding protein GGA GO:0005768//endosome;GO:0005768//endosome - GO:0015031//protein transport;GO:0015031//protein transport "gi|148678878|gb|EDL10825.1|/0/target of myb1 homolog (chicken), isoform CRA_b [Mus musculus]" 14066 1876 5.363333333 6.96 0.375957386 Up 0.464562413 F3 coagulation factor III K03901|1|2e-164|582|mmu:14066|coagulation factor III (tissue factor) - - - - 100124641 109 0.38 0.01 -5.247927513 Down 0.464402572 Mir692-3 microRNA 692-3 K13625|1|1e-09|63.5|cmy:102935925|ferritin light chain - - - "gi|148701888|gb|EDL33835.1|/1.21436e-08/mCG118431, partial [Mus musculus]" 22271 1269.43 3.063333333 4.286666667 0.484753876 Up 0.464402572 Upp1 uridine phosphorylase 1 K00757|1|7e-171|602|mmu:22271|uridine phosphorylase [EC:2.4.2.3] GO:0044424;GO:0044424;GO:0044424 "GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups" GO:0046131;GO:0009117//nucleotide metabolic process;GO:0009267//cellular response to starvation;GO:0046131;GO:0009117//nucleotide metabolic process;GO:0009267//cellular response to starvation;GO:0046131;GO:0009117//nucleotide metabolic process;GO:0009267//cellular response to starvation gi|226874855|ref|NP_033503.2|/5.9281e-170/uridine phosphorylase 1 [Mus musculus] 11537 924 0.383333333 0.01 -5.26052755 Down 0.464402572 Cfd complement factor D (adipsin) K01334|1|2e-152|540|mmu:11537|component factor D [EC:3.4.21.46] GO:0044421;GO:0044421 GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0006952//defense response;GO:0006956//complement activation;GO:0007166//cell surface receptor signaling pathway;GO:0006952//defense response;GO:0006956//complement activation;GO:0007166//cell surface receptor signaling pathway gi|7304867|ref|NP_038487.1|/1.67986e-151/complement factor D isoform 1 precursor [Mus musculus] 735288 109 0.38 0.01 -5.247927513 Down 0.464402572 Mir692-2 microRNA 692-2 K13625|1|1e-09|63.5|cmy:102935925|ferritin light chain - - - "gi|148701888|gb|EDL33835.1|/1.21436e-08/mCG118431, partial [Mus musculus]" 19044 1821 7.226666667 9.126666667 0.33675769 Up 0.464364963 Ppox protoporphyrinogen oxidase K00231|1|0.0|860|mmu:19044|oxygen-dependent protoporphyrinogen oxidase [EC:1.3.3.4] GO:0031304//intrinsic component of mitochondrial inner membrane "GO:0016634//oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor" GO:0044710;GO:0006779//porphyrin-containing compound biosynthetic process gi|6679445|ref|NP_032937.1|/0/protoporphyrinogen oxidase [Mus musculus] 23959 3580 5.88 4.416666667 -0.412858201 Down 0.464205122 Nt5e "5' nucleotidase, ecto" K19970|1|0.0|1122|mmu:23959|5'-nucleotidase [EC:3.1.3.5] GO:0031988//membrane-bounded vesicle;GO:0044424;GO:0031224//intrinsic component of membrane GO:0005506//iron ion binding;GO:0036094//small molecule binding;GO:0008252//nucleotidase activity GO:0044260;GO:0007417//central nervous system development;GO:0008610//lipid biosynthetic process;GO:0006213//pyrimidine nucleoside metabolic process;GO:0046085//adenosine metabolic process;GO:0010038//response to metal ion;GO:0009112;GO:0006954//inflammatory response;GO:0009154//purine ribonucleotide catabolic process gi|6754900|ref|NP_035981.1|/0/5'-nucleotidase precursor [Mus musculus] 70110 1360 16.34 19.75333333 0.273688142 Up 0.463979465 Ifi35 interferon-induced protein 35 - GO:0043231//intracellular membrane-bounded organelle - - gi|21312544|ref|NP_081596.1|/9.8371e-158/interferon-induced 35 kDa protein homolog [Mus musculus] 242377 5578 14.55666667 11.87666667 -0.293550048 Down 0.463866637 Pm20d2 peptidase M20 domain containing 2 - - GO:0003824//catalytic activity - gi|298493323|ref|NP_001030039.2|/0/peptidase M20 domain-containing protein 2 [Mus musculus] 378937 1904 0.986666667 1.793333333 0.862008997 Up 0.463791418 Lrrc24 leucine rich repeat containing 24 K19511|1|2e-28|130|dvi:Dvir_GJ12983|peroxidase [EC:1.11.1.7] - - - - 110750 3604 16.82666667 13.81333333 -0.284687907 Down 0.463772613 Cse1l chromosome segregation 1-like (S. cerevisiae) K18423|1|0.0|1817|mmu:110750|exportin-2 (importin alpha re-exporter) GO:0005635//nuclear envelope GO:0005488//binding;GO:0005049//nuclear export signal receptor activity GO:0012501//programmed cell death;GO:0015031//protein transport gi|532040142|ref|XP_005362925.1|/0/PREDICTED: exportin-2 [Microtus ochrogaster] 667728 2983 2.82 1.833333333 -0.621226045 Down 0.463735003 Hist1h2al "histone cluster 1, H2al" K11251|1|3e-53|213|ssc:100511884|histone H2A GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|927153975|ref|XP_013832965.1|/3.00634e-52/PREDICTED: histone H2A type 1-H-like isoform X1 [Sus scrofa] 102631696 1387 0.906666667 1.693333333 0.901221846 Up 0.463640979 Gm29968 "predicted gene, 29968" K10517|1|4e-07|58.5|cfa:485980|zinc finger and BTB domain-containing protein 46 - GO:0003676//nucleic acid binding;GO:0034061//DNA polymerase activity GO:0006260//DNA replication "gi|68062522|ref|XP_673268.1|/1.72181e-32/hypothetical protein [Plasmodium berghei strain ANKA], partial [Plasmodium berghei ANKA]" 77015 2662 6.503333333 8.303333333 0.352511244 Up 0.463612772 Mpped2 metallophosphoesterase domain containing 2 - - GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0003824//catalytic activity GO:0048731//system development;GO:0048731//system development gi|507699538|ref|XP_004644164.1|/4.33107e-180/PREDICTED: metallophosphoesterase MPPED2 [Octodon degus] 20813 790 56.83 66.78666667 0.232907395 Up 0.463584565 Srp14 signal recognition particle 14 K03104|1|6e-46|186|rno:296076|signal recognition particle subunit SRP14 GO:0048500//signal recognition particle GO:0005048//signal sequence binding;GO:0003723//RNA binding GO:0006613//cotranslational protein targeting to membrane;GO:0042221//response to chemical "gi|157829621|pdb|1914|A/1.86619e-46/Chain A, Signal Recognition Particle Alu Rna Binding Heterodimer, Srp914" 66505 4008.77 29.90666667 25.12 -0.251630655 Down 0.463471736 Zmynd11 "zinc finger, MYND domain containing 11" K20289|1|3e-25|120|smm:Smp_143570|conserved oligomeric Golgi complex subunit 2 GO:0031981//nuclear lumen;GO:0043232;GO:0031981//nuclear lumen;GO:0043232 GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding "GO:0007254//JNK cascade;GO:0097191//extrinsic apoptotic signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization;GO:0007254//JNK cascade;GO:0097191//extrinsic apoptotic signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" "gi|148700349|gb|EDL32296.1|/0/zinc finger, MYND domain containing 11, isoform CRA_e, partial [Mus musculus]" 71670 1292.17 30 25.25333333 -0.248488671 Down 0.463095641 Acy3 aspartoacylase (aminoacylase) 3 K18458|1|0.0|651|mmu:71670|N-acyl-aromatic-L-amino acid amidohydrolase [EC:3.5.1.114] GO:0044459;GO:0044424;GO:0044459;GO:0044424;GO:0044459;GO:0044424;GO:0044459;GO:0044424 "GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005515//protein binding;GO:0043169//cation binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005515//protein binding;GO:0043169//cation binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005515//protein binding;GO:0043169//cation binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005515//protein binding;GO:0043169//cation binding" - gi|699045653|ref|NP_001289411.1|/9.51989e-111/N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) isoform 2 [Mus musculus] 77124 1542 56.73 66.35333333 0.226057079 Up 0.462954605 9130221H12Rik RIKEN cDNA 9130221H12 gene K08822|1|2e-29|133|mmu:606496|glycogen synthase kinase 3 alpha [EC:2.7.11.26] - - - - 67458 2734 25.07 29.8 0.249350335 Up 0.462945203 Ergic1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 K20365|1|2e-164|582|ngi:103748234|endoplasmic reticulum-Golgi intermediate compartment protein 1 GO:0012505//endomembrane system;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0016482//cytosolic transport gi|50510831|dbj|BAD32401.1|/4.31852e-167/mKIAA1181 protein [Mus musculus] 140546 1512.23 55.30333333 64.85666667 0.229888438 Up 0.462879386 Eri3 exoribonuclease 3 K18418|1|0.0|645|mmu:140546|ERI1 exoribonuclease 3 [EC:3.1.-.-] GO:0016020//membrane;GO:0044464;GO:0016020//membrane;GO:0044464;GO:0016020//membrane;GO:0044464;GO:0044464 GO:0097159//organic cyclic compound binding;GO:0004518//nuclease activity;GO:0043169//cation binding;GO:0004518//nuclease activity;GO:0043169//cation binding;GO:0004518//nuclease activity;GO:0043169//cation binding;GO:0097159//organic cyclic compound binding;GO:0004518//nuclease activity;GO:0043169//cation binding - gi|2852640|gb|AAC19158.1|/0/unknown [Homo sapiens] 66950 4204 16.48 19.81666667 0.265998067 Up 0.462869984 Tmem206 transmembrane protein 206 - GO:0031224//intrinsic component of membrane - - gi|13385348|ref|NP_080140.1|/4.41989e-161/transmembrane protein 206 [Mus musculus] 234678 2873 9.253333333 11.50333333 0.314006906 Up 0.462616119 D230025D16Rik RIKEN cDNA D230025D16 gene - GO:0043005//neuron projection;GO:0008021//synaptic vesicle GO:0005102//receptor binding GO:0006886//intracellular protein transport "gi|148679304|gb|EDL11251.1|/0/mCG23527, isoform CRA_a, partial [Mus musculus]" 68721 1779.99 9.426666667 11.67333333 0.308396964 Up 0.462616119 1110032A03Rik RIKEN cDNA 1110032A03 gene K01580|1|4e-20|102|ocu:100355864|glutamate decarboxylase [EC:4.1.1.15] GO:0043231//intracellular membrane-bounded organelle - - gi|74141771|dbj|BAE38625.1|/3.52916e-100/unnamed protein product [Mus musculus] 69368 4566 1.76 2.726666667 0.631562914 Up 0.462324646 Wdfy1 WD repeat and FYVE domain containing 1 K16482|1|4e-07|57.0|phu:Phum_PHUM308740|centriolar protein POC1 - - - - 72357 1350 16.38 19.68666667 0.265283499 Up 0.462315243 2210016L21Rik RIKEN cDNA 2210016L21 gene - - - - gi|123795362|sp|Q3UY34.1|CL043_MOUSE/1.58802e-83/RecName: Full=Uncharacterized protein C12orf43 homolog 74654 1341 2.113333333 1.25 -0.757592245 Down 0.462305841 4930455H04Rik RIKEN cDNA 4930455H04 gene - - - - - 83382 1849 1.38 2.27 0.718024031 Up 0.462296438 Siglece sialic acid binding Ig-like lectin E K06748|1|0.0|641|cge:100764017|sialic acid binding Ig-like lectin 8 GO:0031224//intrinsic component of membrane GO:0038023//signaling receptor activity;GO:0030246//carbohydrate binding GO:0022610;GO:0007154//cell communication "gi|148690724|gb|EDL22671.1|/0/sialic acid binding Ig-like lectin E, partial [Mus musculus]" 69161 1107 9.173333333 11.41 0.314780822 Up 0.462258829 Manbal "mannosidase, beta A, lysosomal-like" - GO:0031224//intrinsic component of membrane - - "gi|148674286|gb|EDL06233.1|/2.747e-40/mannosidase, beta A, lysosomal-like, isoform CRA_b, partial [Mus musculus]" 69635 5730.97 11.50333333 9.266666667 -0.311929591 Down 0.462258829 Dapk1 death associated protein kinase 1 K08803|1|0.0|2769|mmu:69635|death-associated protein kinase [EC:2.7.11.1] - - - gi|552953823|ref|NP_001272846.1|/0/death-associated protein kinase 1 isoform 2 [Mus musculus] 110595 1416 63.6 54.37333333 -0.226127491 Down 0.462089586 Timp4 tissue inhibitor of metalloproteinase 4 K16866|1|3e-52|208|pbi:103062057|metalloproteinase inhibitor 3 GO:0044421;GO:0030016//myofibril GO:0043169//cation binding;GO:0004866//endopeptidase inhibitor activity GO:0009725//response to hormone;GO:0002237//response to molecule of bacterial origin;GO:0044702//single organism reproductive process;GO:0007399//nervous system development gi|110625888|ref|NP_542370.3|/5.73327e-124/metalloproteinase inhibitor 4 precursor [Mus musculus] 217353 2325.3 4.896666667 6.406666667 0.38777394 Up 0.462080184 Tmc6 transmembrane channel-like gene family 6 K18730|1|5e-18|96.3|chx:102188188|PERQ amino acid-rich with GYF domain-containing protein;K10877|2|4e-06|56.6|tsp:Tsp_10860|DNA repair and recombination protein RAD54B [EC:3.6.4.-] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|264681552|ref|NP_663414.3|/0/transmembrane channel-like protein 6 isoform 1 [Mus musculus] 19141 1874 54.19666667 63.34666667 0.225064584 Up 0.461882733 Lgmn legumain K01369|1|0.0|838|mmu:19141|legumain [EC:3.4.22.34] GO:0005768//endosome;GO:0000323//lytic vacuole GO:0004175//endopeptidase activity GO:0035264//multicellular organism growth;GO:0019538//protein metabolic process;GO:0042221//response to chemical;GO:0043066//negative regulation of apoptotic process "gi|586500378|pdb|4NOK|A/0/Chain A, Crystal Structure Of Proenzyme Asparaginyl Endopeptidase (aep) /legumain At Ph 7.5" 13198 851.66 16.13 19.41333333 0.267301416 Up 0.461779307 Ddit3 DNA-damage inducible transcript 3 K04452|1|2e-65|251|mmu:13198|DNA damage-inducible transcript 3 GO:0005768//endosome;GO:0005768//endosome GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003677//DNA binding GO:0043065//positive regulation of apoptotic process;GO:0045445//myoblast differentiation;GO:0034976//response to endoplasmic reticulum stress;GO:0014075//response to amine;GO:0009790//embryo development;GO:0031667//response to nutrient levels;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0001819//positive regulation of cytokine production;GO:0006984//ER-nucleus signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0000302//response to reactive oxygen species;GO:0051283//negative regulation of sequestering of calcium ion;GO:0007049//cell cycle;GO:0006366//transcription from RNA polymerase II promoter;GO:0035966//response to topologically incorrect protein;GO:0051093//negative regulation of developmental process;GO:0001568//blood vessel development;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0045445//myoblast differentiation;GO:0034976//response to endoplasmic reticulum stress;GO:0014075//response to amine;GO:0009790//embryo development;GO:0031667//response to nutrient levels;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0001819//positive regulation of cytokine production;GO:0006984//ER-nucleus signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0000302//response to reactive oxygen species;GO:0051283//negative regulation of sequestering of calcium ion;GO:0007049//cell cycle;GO:0006366//transcription from RNA polymerase II promoter;GO:0035966//response to topologically incorrect protein;GO:0051093//negative regulation of developmental process;GO:0001568//blood vessel development;GO:0006511//ubiquitin-dependent protein catabolic process "gi|148692548|gb|EDL24495.1|/4.04357e-66/DNA-damage inducible transcript 3, isoform CRA_b, partial [Mus musculus]" 12045 764 0.666666667 1.37 1.039138394 Up 0.461741698 Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b K02162|1|1e-95|351|mmu:12045|hematopoietic Bcl-2-related protein A1 GO:0044424 GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0004869//cysteine-type endopeptidase inhibitor activity GO:0030098//lymphocyte differentiation;GO:0006915//apoptotic process;GO:0050851//antigen receptor-mediated signaling pathway gi|160415219|ref|NP_031560.2|/1.00063e-94/B-cell leukemia/lymphoma 2 related protein A1b [Mus musculus] 229706 6331.87 1.44 2.34 0.700439718 Up 0.461694686 Slc6a17 "solute carrier family 6 (neurotransmitter transporter), member 17" "K05048|1|0.0|1351|mmu:229706|solute carrier family 6 (neurotransmitter transporter, amino acid/orphan) member 15/16/17/18/20" GO:0008021//synaptic vesicle;GO:0016021//integral component of membrane;GO:0008021//synaptic vesicle;GO:0016021//integral component of membrane;GO:0008021//synaptic vesicle;GO:0016021//integral component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0006865//amino acid transport;GO:0006812//cation transport;GO:0006865//amino acid transport;GO:0006812//cation transport;GO:0006865//amino acid transport;GO:0006812//cation transport "gi|148669961|gb|EDL01908.1|/0/solute carrier family 6 (neurotransmitter transporter), member 17, isoform CRA_c, partial [Mus musculus]" 11668 2032 14.45 11.85 -0.286182434 Down 0.461647674 Aldh1a1 "aldehyde dehydrogenase family 1, subfamily A1" K07249|1|0.0|977|mmu:11668|retinal dehydrogenase [EC:1.2.1.36] GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0004029//aldehyde dehydrogenase (NAD) activity GO:0048562//embryonic organ morphogenesis;GO:0043627//response to estrogen;GO:0022602//ovulation cycle process;GO:0006915//apoptotic process;GO:0002138//retinoic acid biosynthetic process;GO:0048565//digestive tract development;GO:0097305//response to alcohol;GO:0016331//morphogenesis of embryonic epithelium;GO:0006950//response to stress;GO:0051260//protein homooligomerization "gi|28386049|gb|AAH44729.1|/0/Aldh1a1 protein, partial [Mus musculus]" 79043 1888.63 22.75666667 19.00666667 -0.259783713 Down 0.461497236 Spsb3 splA/ryanodine receptor domain and SOCS box containing 3 K10345|1|0.0|651|rno:302981|SPRY domain-containing SOCS box protein 3 - - - gi|254939629|ref|NP_081417.2|/0/SPRY domain-containing SOCS box protein 3 isoform 3 [Mus musculus] 12978 3875 13.51666667 16.40333333 0.279249602 Up 0.461412614 Csf1r colony stimulating factor 1 receptor K05090|1|0.0|1896|mmu:12978|macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1] GO:0031224//intrinsic component of membrane;GO:0044464;GO:0043234//protein complex GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032550;GO:0042802//identical protein binding GO:0048017//inositol lipid-mediated signaling;GO:0031532//actin cytoskeleton reorganization;GO:0014706//striated muscle tissue development;GO:0006952//defense response;GO:0032844//regulation of homeostatic process;GO:0036005;GO:0043410//positive regulation of MAPK cascade;GO:0019221//cytokine-mediated signaling pathway;GO:0016477//cell migration;GO:0034331;GO:0032722//positive regulation of chemokine production;GO:0006650//glycerophospholipid metabolic process;GO:0008283//cell proliferation;GO:0022604//regulation of cell morphogenesis;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0045860//positive regulation of protein kinase activity;GO:0030030//cell projection organization;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0040017//positive regulation of locomotion gi|44890287|gb|AAH66863.1|/0/Colony stimulating factor 1 receptor [Mus musculus] 19275 3536 2.64 1.69 -0.643514683 Down 0.461280981 Ptprn "protein tyrosine phosphatase, receptor type, N" K07817|1|0.0|1614|mmu:19275|receptor-type tyrosine-protein phosphatase N [EC:3.1.3.48] GO:0031224//intrinsic component of membrane GO:0008092//cytoskeletal protein binding;GO:0019899//enzyme binding;GO:0004721//phosphoprotein phosphatase activity GO:0006979//response to oxidative stress;GO:0035556//intracellular signal transduction;GO:0048545//response to steroid hormone;GO:0046683//response to organophosphorus;GO:0009746;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0006464//cellular protein modification process;GO:0043434//response to peptide hormone;GO:0006796//phosphate-containing compound metabolic process "gi|148667976|gb|EDL00393.1|/0/protein tyrosine phosphatase, receptor type, N, partial [Mus musculus]" 68738 3594 125.4266667 145.9466667 0.218597152 Up 0.461271578 Acss1 acyl-CoA synthetase short-chain family member 1 K01895|1|0.0|1309|mmu:68738|acetyl-CoA synthetase [EC:6.2.1.1] GO:0044429 GO:0032550;GO:0016405//CoA-ligase activity GO:0019541//propionate metabolic process;GO:0006084//acetyl-CoA metabolic process;GO:0006067//ethanol metabolic process;GO:0006083//acetate metabolic process gi|74196453|dbj|BAE34365.1|/0/unnamed protein product [Mus musculus] 109305 1871 9.35 11.55666667 0.305687066 Up 0.461102336 Orai1 ORAI calcium release-activated calcium modulator 1 K16056|1|3e-142|508|mmu:109305|calcium release-activated calcium channel protein 1 GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0016021//integral component of membrane GO:0005488//binding;GO:0005262//calcium channel activity GO:0006816//calcium ion transport "gi|148687708|gb|EDL19655.1|/2.40243e-155/transmembrane protein 142A, isoform CRA_a, partial [Mus musculus]" 215615 2301 15.83 19.07 0.268643588 Up 0.461045921 Rnpep arginyl aminopeptidase (aminopeptidase B) K01260|1|0.0|1295|mmu:215615|aminopeptidase B [EC:3.4.11.6] "GO:0009986//cell surface;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0042995//cell projection;GO:0016020//membrane;GO:0044421;GO:0009986//cell surface;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0042995//cell projection;GO:0016020//membrane;GO:0044421" GO:0046914//transition metal ion binding;GO:0004177//aminopeptidase activity;GO:0033218//amide binding;GO:0046914//transition metal ion binding;GO:0004177//aminopeptidase activity;GO:0033218//amide binding GO:0043010//camera-type eye development;GO:0008217//regulation of blood pressure;GO:0051604//protein maturation;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0043010//camera-type eye development;GO:0008217//regulation of blood pressure;GO:0051604//protein maturation;GO:0006636//unsaturated fatty acid biosynthetic process gi|227499234|ref|NP_001153096.1|/0/aminopeptidase B isoform 2 [Mus musculus] 74148 5399 135.27 116.1633333 -0.219687158 Down 0.460632216 Cluh clustered mitochondria (cluA/CLU1) homolog K03255|1|0.0|2624|mmu:74148|protein TIF31 - - - gi|124487201|ref|NP_001074627.1|/0/clustered mitochondria protein homolog [Mus musculus] 56530 1017 18.93333333 22.62666667 0.257095635 Up 0.460622814 Cnpy2 canopy FGF signaling regulator 2 K12571|1|4e-63|244|clv:102085441|PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4];K01647|3|6e-20|100|cfa:474403|citrate synthase [EC:2.3.3.1] - - - - 54604 12139 8.046666667 6.296666667 -0.353802974 Down 0.460556997 Pcnx pecanex homolog (Drosophila) - - - - "gi|148670777|gb|EDL02724.1|/0/pecanex homolog (Drosophila), isoform CRA_b, partial [Mus musculus]" 17112 1902 13.24 16.09333333 0.281560053 Up 0.460444169 Tm4sf1 transmembrane 4 superfamily member 1 - GO:0031224//intrinsic component of membrane - - gi|6678762|ref|NP_032562.1|/2.64483e-109/transmembrane 4 L6 family member 1 [Mus musculus] 117167 3140 18.88333333 15.67333333 -0.268801417 Down 0.460425364 Steap4 STEAP family member 4 K19876|1|0.0|911|mmu:117167|metalloreductase STEAP4 [EC:1.16.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane GO:0043169//cation binding;GO:0036094//small molecule binding;GO:0003824//catalytic activity GO:0044765//single-organism transport;GO:0030154//cell differentiation;GO:0055080//cation homeostasis;GO:0044710 gi|31981509|ref|NP_473439.2|/0/metalloreductase STEAP4 [Mus musculus] 239650 2345 0.36 0.973333333 1.434937057 Up 0.460303133 Ccdc184 coiled-coil domain containing 184 - GO:0044424 - - gi|226053365|ref|NP_808384.2|/1.26858e-95/coiled-coil domain-containing protein 184 [Mus musculus] 18637 745 49.95333333 58.50333333 0.227937876 Up 0.460274926 Pfdn2 prefoldin 2 K09549|1|6e-58|226|rno:685607|prefoldin subunit 2 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005515//protein binding GO:0006458//'de novo' protein folding gi|3212116|emb|CAA76760.1|/4.65614e-57/prefoldin subunit 2 [Mus musculus] 217718 5403 38.25666667 32.49 -0.235715432 Down 0.460246719 Nek9 NIMA (never in mitosis gene a)-related expressed kinase 9 K08857|1|0.0|1749|mmu:217718|NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity;GO:0019900//kinase binding GO:0000087//mitotic M phase;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process gi|50511231|dbj|BAD32601.1|/0/mKIAA1995 protein [Mus musculus] 78309 7862 7.003333333 5.403333333 -0.374192071 Down 0.460227914 Cul9 cullin 9 K11970|1|0.0|4615|mmu:78309|p53-associated parkin-like cytoplasmic protein - - - - 230775 5011 0.426666667 1.053333333 1.303780748 Up 0.460227914 Adgrb2 adhesion G protein-coupled receptor B2 K04597|1|0.0|2859|mmu:230775|brain-specific angiogenesis inhibitor 2 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0001525//angiogenesis;GO:0007399//nervous system development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0007399//nervous system development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0007399//nervous system development;GO:0007186//G-protein coupled receptor signaling pathway gi|595582212|ref|NP_001277644.1|/0/adhesion G protein-coupled receptor B2 isoform 3 precursor [Mus musculus] 229906 1267 15.44666667 18.65 0.271880087 Up 0.460152695 Gtf2b general transcription factor IIB K03124|1|5e-170|599|mcf:101865381|transcription initiation factor TFIIB GO:0031981//nuclear lumen "GO:0046914//transition metal ion binding;GO:0008135//translation factor activity, RNA binding;GO:0008134//transcription factor binding" GO:0006412//translation;GO:0006366//transcription from RNA polymerase II promoter gi|829971448|ref|XP_012604694.1|/2.24457e-169/PREDICTED: transcription initiation factor IIB isoform X3 [Microcebus murinus] 12808 5621.21 2.193333333 3.236666667 0.561383712 Up 0.45993644 Cobl cordon-bleu WH2 repeat K18623|1|0.0|2310|mmu:12808|protein cordon-bleu GO:0030426//growth cone;GO:0015629//actin cytoskeleton;GO:0044297//cell body;GO:0044444//cytoplasmic part;GO:0030426//growth cone;GO:0015629//actin cytoskeleton;GO:0044297//cell body;GO:0044444//cytoplasmic part;GO:0030426//growth cone;GO:0015629//actin cytoskeleton;GO:0044297//cell body;GO:0044444//cytoplasmic part GO:0003779//actin binding;GO:0003779//actin binding;GO:0003779//actin binding GO:0014020;GO:0008154//actin polymerization or depolymerization;GO:0010976//positive regulation of neuron projection development;GO:0048668//collateral sprouting;GO:0014020;GO:0008154//actin polymerization or depolymerization;GO:0010976//positive regulation of neuron projection development;GO:0048668//collateral sprouting;GO:0014020;GO:0008154//actin polymerization or depolymerization;GO:0010976//positive regulation of neuron projection development;GO:0048668//collateral sprouting gi|28972325|dbj|BAC65616.1|/0/mKIAA0633 protein [Mus musculus] 108664 2063 11.11666667 8.936666667 -0.314915542 Down 0.459889428 Atp6v1h "ATPase, H+ transporting, lysosomal V1 subunit H" K02144|1|0.0|963|mmu:108664|V-type H+-transporting ATPase subunit H GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0019829//cation-transporting ATPase activity;GO:0019829//cation-transporting ATPase activity;GO:0005488//binding "GO:0016192//vesicle-mediated transport;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0015031//protein transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006996//organelle organization;GO:0016192//vesicle-mediated transport;GO:0050688//regulation of defense response to virus;GO:0051452//intracellular pH reduction;GO:0009154//purine ribonucleotide catabolic process;GO:0019222//regulation of metabolic process;GO:0044403//symbiosis, encompassing mutualism through parasitism;GO:0006875//cellular metal ion homeostasis" gi|882939074|ref|NP_001297371.1|/0/V-type proton ATPase subunit H isoform 2 [Mus musculus] 71660 708 23.44666667 27.86333333 0.248985026 Up 0.459842416 Rarres2 retinoic acid receptor responder (tazarotene induced) 2 K10044|1|1e-91|338|mmu:71660|retinoic acid receptor responder protein 2 - GO:0005515//protein binding GO:0048565//digestive tract development;GO:0043009//chordate embryonic development;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0016101//diterpenoid metabolic process;GO:0006950//response to stress;GO:0045444//fat cell differentiation "gi|148666128|gb|EDK98544.1|/1.36862e-92/retinoic acid receptor responder (tazarotene induced) 2, isoform CRA_b, partial [Mus musculus]" 66124 949.55 47.74333333 56.13666667 0.233644105 Up 0.459833014 Josd2 Josephin domain containing 2 K15235|1|4e-81|303|mmu:66124|josephin [EC:3.4.19.12] - GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity GO:0070646//protein modification by small protein removal;GO:0070646//protein modification by small protein removal;GO:0070646//protein modification by small protein removal;GO:0070646//protein modification by small protein removal;GO:0070646//protein modification by small protein removal gi|568948257|ref|XP_006541135.1|/5.27606e-84/PREDICTED: josephin-2 isoform X3 [Mus musculus] 384071 2683 104.6666667 122.28 0.224386399 Up 0.459823611 Slc25a34 "solute carrier family 25, member 34" "K15117|1|1e-169|599|mmu:384071|solute carrier family 25, member 34/35" GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0051234//establishment of localization gi|85719318|ref|NP_001013802.1|/1.00618e-168/solute carrier family 25 member 34 [Mus musculus] 116748 927 9.173333333 11.34 0.305902671 Up 0.459513333 Lsm10 U7 snRNP-specific Sm-like protein LSM10 - GO:0030532//small nuclear ribonucleoprotein complex;GO:0016604//nuclear body;GO:0030532//small nuclear ribonucleoprotein complex;GO:0016604//nuclear body GO:0003723//RNA binding;GO:0003723//RNA binding GO:0051320;GO:0006396//RNA processing;GO:0051320;GO:0006396//RNA processing gi|537236443|gb|ERE85660.1|/6.56362e-55/protein OSCP1-like protein [Cricetulus griseus] 245404 3498 1.293333333 0.613333333 -1.076350886 Down 0.459466321 Dcaf12l1 DDB1 and CUL4 associated factor 12-like 1 K11803|1|2e-141|506|mdo:100010360|WD repeat-containing protein 40A - - - gi|300192937|ref|NP_848854.3|/0/DDB1- and CUL4-associated factor 12-like protein 1 [Mus musculus] 102465889 137 0.01 0.37 5.209453366 Up 0.459456918 Mir8098 microRNA 8098 - - - - - 108089 5148.16 4.66 3.406666667 -0.451969164 Down 0.459428711 Rnf144a ring finger protein 144A K11975|1|1e-163|580|cfa:609037|E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.27] - - - - 20686 700 3.396666667 4.646666667 0.45207651 Up 0.459428711 Spa17 sperm autoantigenic protein 17 - GO:0005929//cilium - GO:0048870//cell motility;GO:0035036//sperm-egg recognition gi|6755614|ref|NP_035579.1|/5.2658e-57/sperm surface protein Sp17 [Mus musculus] 53416 3268 37.40666667 31.76 -0.2360845 Down 0.459400504 Stk39 serine/threonine kinase 39 K08835|1|0.0|986|mmu:53416|serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0043232 GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0019900//kinase binding GO:0006954//inflammatory response;GO:0006813//potassium ion transport;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction "gi|148695071|gb|EDL27018.1|/0/serine/threonine kinase 39, STE20/SPS1 homolog (yeast), isoform CRA_a, partial [Mus musculus]" 117109 991 11.20666667 13.72333333 0.292273724 Up 0.459334687 Pop5 "processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)" K03537|1|2e-93|344|mmu:117109|ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] GO:0030681//multimeric ribonuclease P complex;GO:0043231//intracellular membrane-bounded organelle GO:0004549//tRNA-specific ribonuclease activity GO:0006399//tRNA metabolic process gi|20270200|ref|NP_080674.1|/1.51078e-92/ribonuclease P/MRP protein subunit POP5 [Mus musculus] 14533 550 101.5866667 118.2 0.218518976 Up 0.459297078 Bloc1s1 "biogenesis of lysosomal organelles complex-1, subunit 1" K20185|1|5e-56|218|rro:104673713|biogenesis of lysosome-related organelles complex 1 subunit 1 GO:0005764//lysosome;GO:0031082;GO:0005740//mitochondrial envelope GO:0005488//binding GO:0030030//cell projection organization;GO:0006473//protein acetylation;GO:0045333//cellular respiration;GO:0008088//axo-dendritic transport;GO:0048489//synaptic vesicle transport;GO:0048753//pigment granule organization;GO:0048193//Golgi vesicle transport;GO:0033363//secretory granule organization gi|966972759|ref|XP_015007402.1|/3.35527e-55/PREDICTED: biogenesis of lysosome-related organelles complex 1 subunit 1 [Macaca mulatta] 51801 2549 3.283333333 2.236666667 -0.553810958 Down 0.459250066 Ramp1 receptor (calcitonin) activity modifying protein 1 K08447|1|6e-33|143|mmu:51801|receptor activity modifying protein 1 GO:0031224//intrinsic component of membrane;GO:0005622//intracellular;GO:0043234//protein complex;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0005622//intracellular;GO:0043234//protein complex;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0005622//intracellular;GO:0043234//protein complex;GO:0044421 GO:0004930//G-protein coupled receptor activity;GO:0046983//protein dimerization activity;GO:0022892//substrate-specific transporter activity;GO:0001664//G-protein coupled receptor binding;GO:0004930//G-protein coupled receptor activity;GO:0046983//protein dimerization activity;GO:0022892//substrate-specific transporter activity;GO:0001664//G-protein coupled receptor binding;GO:0004930//G-protein coupled receptor activity;GO:0046983//protein dimerization activity;GO:0022892//substrate-specific transporter activity;GO:0001664//G-protein coupled receptor binding GO:0007186//G-protein coupled receptor signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:0007009//plasma membrane organization;GO:0015031//protein transport;GO:0006171//cAMP biosynthetic process;GO:0006486//protein glycosylation;GO:0070838//divalent metal ion transport;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:0007009//plasma membrane organization;GO:0015031//protein transport;GO:0006171//cAMP biosynthetic process;GO:0006486//protein glycosylation;GO:0070838//divalent metal ion transport;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:0007009//plasma membrane organization;GO:0015031//protein transport;GO:0006171//cAMP biosynthetic process;GO:0006486//protein glycosylation;GO:0070838//divalent metal ion transport;GO:0048646//anatomical structure formation involved in morphogenesis gi|74188380|dbj|BAE25837.1|/3.49306e-64/unnamed protein product [Mus musculus] 100233175 1162 2.263333333 3.31 0.548382143 Up 0.459250066 AK010878 cDNA sequence AK010878 - - - GO:0006915//apoptotic process gi|219283242|ref|NP_001136410.1|/2.04533e-33/uncharacterized protein C14orf142 homolog [Mus musculus] 30949 1369 10.19 12.50333333 0.295158711 Up 0.459203054 Lcmt1 leucine carboxyl methyltransferase 1 K18203|1|0.0|645|mmu:30949|[phosphatase 2A protein]-leucine-carboxy methyltransferase [EC:2.1.1.233] - GO:0005488//binding;GO:0051998//protein carboxyl O-methyltransferase activity GO:0006915//apoptotic process;GO:0006479//protein methylation;GO:0006461//protein complex assembly;GO:0007346//regulation of mitotic cell cycle gi|42794773|ref|NP_079580.2|/0/leucine carboxyl methyltransferase 1 [Mus musculus] 20602 8528.72 36.78666667 31.17333333 -0.238870527 Down 0.459156042 Ncor2 nuclear receptor co-repressor 2 K06065|1|0.0|3390|mmu:20602|nuclear receptor co-repressor 2 - - - "gi|148687620|gb|EDL19567.1|/0/nuclear receptor co-repressor 2, isoform CRA_c, partial [Mus musculus]" 380840 1515 12.91666667 15.70333333 0.281837022 Up 0.459052616 Lyrm4 LYR motif containing 4 - GO:0043231//intracellular membrane-bounded organelle - - "gi|148708964|gb|EDL40910.1|/5.64928e-48/cDNA sequence BC034664, partial [Mus musculus]" 19847 166 0.01 0.366666667 5.196397213 Up 0.459024409 Rnu1b6 U1b6 small nuclear RNA K17540|1|7e-15|51.6|ssc:100737915|inactive serine/threonine-protein kinase TEX14;K06628|3|1e-12|52.8|ocu:103350632|cell division control protein 45;K10393|5|6e-09|46.2|myb:102254543|kinesin family member 2/24 - - - gi|927196956|ref|XP_013836555.1|/6.77302e-14/PREDICTED: inactive serine/threonine-protein kinase TEX14 [Sus scrofa] 18453 2538 97.17666667 113.2733333 0.221126412 Up 0.458996201 P4hb "prolyl 4-hydroxylase, beta polypeptide" K09580|1|0.0|898|mmu:18453|protein disulfide-isomerase A1 [EC:5.3.4.1] GO:0044432;GO:0048770;GO:0016020//membrane "GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups;GO:0019798//procollagen-proline dioxygenase activity;GO:0046983//protein dimerization activity;GO:0015036//disulfide oxidoreductase activity" GO:0044267//cellular protein metabolic process;GO:0019471//4-hydroxyproline metabolic process;GO:0019725//cellular homeostasis;GO:0018904 "gi|148702819|gb|EDL34766.1|/0/prolyl 4-hydroxylase, beta polypeptide, isoform CRA_b, partial [Mus musculus]" 333654 3130 31.46333333 37.03 0.235023027 Up 0.458967994 Ppp1r13l "protein phosphatase 1, regulatory (inhibitor) subunit 13 like" K16823|1|6e-64|248|ptg:102972442|apoptosis-stimulating of p53 protein 2 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding "GO:0012501//programmed cell death;GO:0006941//striated muscle contraction;GO:0043010//camera-type eye development;GO:0042303//molting cycle;GO:0040007//growth;GO:0042592//homeostatic process;GO:0003208//cardiac ventricle morphogenesis;GO:0006351//transcription, DNA-templated;GO:0048738//cardiac muscle tissue development" gi|58082069|ref|NP_001010836.1|/0/relA-associated inhibitor [Mus musculus] 70012 3878 12.24333333 9.94 -0.300678638 Down 0.458855166 Cep85 centrosomal protein 85 K16766|1|0.0|1470|mmu:70012|centrosomal protein CEP85 GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen - - gi|160333470|ref|NP_653110.3|/0/centrosomal protein of 85 kDa [Mus musculus] 13642 4319 8.606666667 6.803333333 -0.339212818 Down 0.458685923 Efnb2 ephrin B2 K05463|1|2e-173|612|mmu:13642|ephrin-B GO:0031224//intrinsic component of membrane GO:0005102//receptor binding GO:0051155//positive regulation of striated muscle cell differentiation;GO:0022610;GO:0006935//chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0002040//sprouting angiogenesis gi|74208930|dbj|BAE21211.1|/0/unnamed protein product [Mus musculus] 69185 1360 2.526666667 3.613333333 0.516095003 Up 0.458685923 Dtwd1 DTW domain containing 1 - - - - gi|21312232|ref|NP_081257.1|/1.84917e-156/DTW domain-containing protein 1 [Mus musculus] 66362 1035 5.036666667 6.556666667 0.380493297 Up 0.458648313 Exosc3 exosome component 3 K03681|1|2e-156|553|mmu:66362|exosome complex component RRP40 GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0000178//exosome (RNase complex) GO:0003676//nucleic acid binding;GO:0004518//nuclease activity "GO:0002699//positive regulation of immune effector process;GO:0034661//ncRNA catabolic process;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0002204//somatic recombination of immunoglobulin genes involved in immune response;GO:0006304//DNA modification;GO:0042254//ribosome biogenesis" gi|39930417|ref|NP_079789.1|/1.77995e-155/exosome complex component RRP40 [Mus musculus] 382083 2555 8.88 11.02666667 0.312365152 Up 0.458610704 Snx22 sorting nexin 22 K17941|1|5e-111|404|mmu:382083|sorting nexin-22/24 - - - "gi|148694166|gb|EDL26113.1|/4.19637e-116/sorting nexin 22, isoform CRA_a, partial [Mus musculus]" 378462 662 10.05333333 12.34666667 0.29644767 Up 0.458450863 Morn2 MORN repeat containing 2 K19755|1|2e-14|80.9|crg:105326805|radial spoke head protein 1 - - - gi|672055229|ref|XP_006239713.2|/8.46432e-92/PREDICTED: MORN repeat-containing protein 2 isoform X1 [Rattus norvegicus] 66391 1350 3.11 4.3 0.467422079 Up 0.458413254 Zbtb11os1 "zinc finger and BTB domain containing 11, opposite strand 1" K10498|1|1e-56|223|tup:102487075|zinc finger and BTB domain-containing protein 11 - - - - 233726 3117 18.08 14.98 -0.271357054 Down 0.45828162 Ipo7 importin 7 K20223|1|0.0|1981|mmu:233726|importin-7 GO:0005635//nuclear envelope GO:0030695//GTPase regulator activity;GO:0022892//substrate-specific transporter activity;GO:0017016//Ras GTPase binding GO:0007154//cell communication;GO:0006886//intracellular protein transport gi|74229034|ref|NP_852658.2|/0/importin-7 [Mus musculus] 72043 3816.05 27.37666667 23.09666667 -0.245262142 Down 0.458244011 Sulf2 sulfatase 2 K14607|1|0.0|1711|mmu:72043|extracellular sulfatase Sulf [EC:3.1.6.-] GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044421;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044421;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044421 GO:0008484//sulfuric ester hydrolase activity;GO:0046872//metal ion binding;GO:0008484//sulfuric ester hydrolase activity;GO:0046872//metal ion binding;GO:0008484//sulfuric ester hydrolase activity;GO:0046872//metal ion binding GO:0002062//chondrocyte differentiation;GO:0006029//proteoglycan metabolic process;GO:0016055//Wnt signaling pathway;GO:0030198//extracellular matrix organization;GO:0014831//gastro-intestinal system smooth muscle contraction;GO:0001819//positive regulation of cytokine production;GO:0097205//renal filtration;GO:0021675//nerve development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0002062//chondrocyte differentiation;GO:0006029//proteoglycan metabolic process;GO:0016055//Wnt signaling pathway;GO:0030198//extracellular matrix organization;GO:0014831//gastro-intestinal system smooth muscle contraction;GO:0001819//positive regulation of cytokine production;GO:0097205//renal filtration;GO:0021675//nerve development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0002062//chondrocyte differentiation;GO:0006029//proteoglycan metabolic process;GO:0016055//Wnt signaling pathway;GO:0030198//extracellular matrix organization;GO:0014831//gastro-intestinal system smooth muscle contraction;GO:0001819//positive regulation of cytokine production;GO:0097205//renal filtration;GO:0021675//nerve development;GO:0008543//fibroblast growth factor receptor signaling pathway gi|357588455|ref|NP_001239508.1|/0/extracellular sulfatase Sulf-2 isoform 2 [Mus musculus] 13244 2005 30.14666667 35.56 0.238256833 Up 0.45792433 Degs1 "delta(4)-desaturase, sphingolipid 1" K04712|1|0.0|689|mmu:13244|sphingolipid Delta-4 desaturase [EC:1.14.-.-] - - - - 13733 3245 2.226666667 3.263333333 0.551460757 Up 0.457764489 Adgre1 adhesion G protein-coupled receptor E1 "K04591|1|0.0|1859|mmu:13733|egf-like module containing, mucin-like, hormone receptor-like 1" GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding;GO:0004888//transmembrane signaling receptor activity GO:0007186//G-protein coupled receptor signaling pathway "gi|148706314|gb|EDL38261.1|/0/EGF-like module containing, mucin-like, hormone receptor-like sequence 1, isoform CRA_c, partial [Mus musculus]" 68034 1696 15.14333333 18.21 0.266048118 Up 0.457576441 Fam122a "family with sequence similarity 122, member A" - - - - - 74013 3689 1.876666667 2.846666667 0.601101148 Up 0.457444808 Rftn2 raftlin family member 2 - GO:0016020//membrane - - gi|110625981|ref|NP_082989.1|/0/raftlin-2 [Mus musculus] 234373 3937.75 9.113333333 7.233333333 -0.3333182 Down 0.457426003 Sugp2 SURP and G patch domain containing 2 "K13166|1|0.0|2060|mmu:234373|splicing factor, arginine/serine-rich 14" GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0006396//RNA processing;GO:0006396//RNA processing "gi|148696857|gb|EDL28804.1|/0/splicing factor, arginine/serine-rich 14, isoform CRA_b, partial [Mus musculus]" 279766 1990.68 8.763333333 10.88 0.312126915 Up 0.457313175 Rhbdd3 rhomboid domain containing 3 - GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane - - gi|28893529|ref|NP_796344.1|/8.3099e-154/rhomboid domain-containing protein 3 isoform a [Mus musculus] 278507 3392 3.38 4.61 0.447743504 Up 0.457181541 Wfikkn2 "WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2" K03909|1|5e-19|99.8|acs:103280510|tissue factor pathway inhibitor - GO:0005488//binding;GO:0004866//endopeptidase inhibitor activity GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0051346//negative regulation of hydrolase activity "gi|568974328|ref|XP_006533560.1|/0/PREDICTED: WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 isoform X2 [Mus musculus]" 74646 3089 28.78 34.05666667 0.242870645 Up 0.457125127 Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 K10343|1|2e-160|569|mmu:74646|SPRY domain-containing SOCS box protein 1/4 - - GO:0007165//signal transduction gi|62088698|dbj|BAD92796.1|/6.81963e-165/SPRY domain-containing SOCS box protein SSB-1 variant [Homo sapiens] 380698 23539.82 94.14 80.58666667 -0.224266693 Down 0.457068713 Obscn "obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF" K17531|1|0.0|1.076e+04|cge:100763304|Obscurin-RhoGEF [EC:2.7.11.1] - - - gi|345842337|ref|NP_954603.3|/0/obscurin isoform 2 [Mus musculus] 68024 619.84 82.15333333 95.63333333 0.219194449 Up 0.457021701 Hist1h2bc "histone cluster 1, H2bc" K11252|1|1e-43|178|pale:102897384|histone H2B GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization;GO:0034728//nucleosome organization gi|524983306|ref|XP_005039649.1|/6.99798e-44/PREDICTED: probable histone H2B.1-like isoform X1 [Ficedula albicollis] 67224 2162 10.8 13.23666667 0.293508548 Up 0.457002896 Med29 mediator complex subunit 29 K15142|1|2e-71|273|mmu:67224|mediator of RNA polymerase II transcription subunit 29 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005488//binding "GO:0006351//transcription, DNA-templated" gi|27754101|ref|NP_080318.2|/1.6663e-70/mediator of RNA polymerase II transcription subunit 29 [Mus musculus] 24055 2966 1.066666667 1.87 0.809928866 Up 0.456965286 Sh3bp2 SH3-domain binding protein 2 K07984|1|0.0|943|mmu:24055|SH3-domain binding protein 2 - GO:0019904//protein domain specific binding;GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0008289//lipid binding - gi|224994231|ref|NP_001139331.1|/0/SH3 domain-binding protein 2 isoform b [Mus musculus] 19326 6065 41.74 49.11666667 0.234782054 Up 0.456843055 Rab11b "RAB11B, member RAS oncogene family" K07905|1|4e-119|433|mmu:19326|Ras-related protein Rab-11B GO:0030666//endocytic vesicle membrane;GO:0005768//endosome GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0032401//establishment of melanosome localization;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction gi|395841772|ref|XP_003793707.1|/1.09029e-131/PREDICTED: ras-related protein Rab-11B [Otolemur garnettii] 99650 1314.75 43.27 50.59 0.225485118 Up 0.456607996 4933434E20Rik RIKEN cDNA 4933434E20 gene - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane "GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0048037//cofactor binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0048037//cofactor binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0048037//cofactor binding" GO:0044710;GO:0044710;GO:0044710 gi|62079073|ref|NP_001014196.1|/1.2169e-100/uncharacterized protein C1orf43 homolog [Rattus norvegicus] 12028 869 17.14666667 20.6 0.264716195 Up 0.45650457 Bax BCL2-associated X protein K02159|1|3e-107|390|mmu:12028|apoptosis regulator BAX GO:0031966//mitochondrial membrane;GO:0097136//Bcl-2 family protein complex;GO:0005829//cytosol;GO:0016021//integral component of membrane GO:0051400//BH domain binding;GO:0042802//identical protein binding;GO:0022803//passive transmembrane transporter activity;GO:0046983//protein dimerization activity "GO:0033598//mammary gland epithelial cell proliferation;GO:0001894//tissue homeostasis;GO:0000737//DNA catabolic process, endonucleolytic;GO:0015980//energy derivation by oxidation of organic compounds;GO:0000266//mitochondrial fission;GO:0034976//response to endoplasmic reticulum stress;GO:0008585//female gonad development;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0009611//response to wounding;GO:0051384//response to glucocorticoid;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0021536//diencephalon development;GO:0035107//appendage morphogenesis;GO:0010623//programmed cell death involved in cell development;GO:0051259//protein oligomerization;GO:0043065//positive regulation of apoptotic process;GO:0048771//tissue remodeling;GO:0043066//negative regulation of apoptotic process;GO:0002339;GO:0001783//B cell apoptotic process;GO:0006970//response to osmotic stress;GO:0042098//T cell proliferation;GO:0097193//intrinsic apoptotic signaling pathway;GO:0010212//response to ionizing radiation;GO:0008637//apoptotic mitochondrial changes;GO:0019740//nitrogen utilization;GO:0070997//neuron death;GO:0008285//negative regulation of cell proliferation;GO:0007049//cell cycle;GO:0048232//male gamete generation;GO:0042391//regulation of membrane potential;GO:0030262//apoptotic nuclear changes;GO:0031334//positive regulation of protein complex assembly;GO:0006839//mitochondrial transport;GO:0034220//ion transmembrane transport;GO:0022603//regulation of anatomical structure morphogenesis;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0048066//developmental pigmentation;GO:0031077//post-embryonic camera-type eye development;GO:0043393//regulation of protein binding;GO:0016477//cell migration;GO:0042476//odontogenesis;GO:0009967//positive regulation of signal transduction;GO:0051204//protein insertion into mitochondrial membrane;GO:0009411//response to UV;GO:0010822//positive regulation of mitochondrion organization;GO:0021543//pallium development;GO:0006664//glycolipid metabolic process;GO:0030540//female genitalia development;GO:0042100//B cell proliferation;GO:0001933//negative regulation of protein phosphorylation;GO:0010038//response to metal ion;GO:0002260//lymphocyte homeostasis;GO:0012502//induction of programmed cell death" gi|6680770|ref|NP_031553.1|/2.51181e-106/apoptosis regulator BAX [Mus musculus] 20703 1442 0.69 0.166666667 -2.049630768 Down 0.45642935 Serpina1d "serine (or cysteine) peptidase inhibitor, clade A, member 1D" K03984|1|0.0|794|mmu:20703|alpha-1-antitrypsin - - - gi|6678085|ref|NP_033272.1|/0/alpha-1-antitrypsin 1-4 precursor [Mus musculus] 15530 14201 90.59 77.74 -0.220694696 Down 0.456391741 Hspg2 perlecan (heparan sulfate proteoglycan 2) K06255|1|0.0|8774|mmu:15530|heparan sulfate proteoglycan 2 (perlecan) GO:0005604//basement membrane;GO:0016020//membrane;GO:0044431//Golgi apparatus part;GO:0031988//membrane-bounded vesicle;GO:0005764//lysosome GO:0005515//protein binding;GO:0043169//cation binding GO:0033036;GO:0006023;GO:0007417//central nervous system development;GO:0048562//embryonic organ morphogenesis;GO:0007507//heart development;GO:0036075;GO:0006790//sulfur compound metabolic process;GO:0006026;GO:0030154//cell differentiation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0043062//extracellular structure organization;GO:0019538//protein metabolic process gi|183979966|ref|NP_032331.2|/0/basement membrane-specific heparan sulfate proteoglycan core protein precursor [Mus musculus] 22171 3798 8.763333333 10.86666667 0.310357823 Up 0.456372936 Tyms thymidylate synthase K00560|1|3e-174|491|mmu:22171|thymidylate synthase [EC:2.1.1.45] GO:0031981//nuclear lumen;GO:0019866//organelle inner membrane;GO:0044429;GO:0031981//nuclear lumen;GO:0019866//organelle inner membrane;GO:0044429 "GO:0042802//identical protein binding;GO:0003723//RNA binding;GO:0019842//vitamin binding;GO:0042083//5,10-methylenetetrahydrofolate-dependent methyltransferase activity;GO:0042802//identical protein binding;GO:0003723//RNA binding;GO:0019842//vitamin binding;GO:0042083//5,10-methylenetetrahydrofolate-dependent methyltransferase activity" GO:0001501//skeletal system development;GO:0019087//transformation of host cell by virus;GO:0002069;GO:0048511//rhythmic process;GO:0009212//pyrimidine deoxyribonucleoside triphosphate biosynthetic process;GO:0040007//growth;GO:0009177;GO:0005975//carbohydrate metabolic process;GO:0033273//response to vitamin;GO:0006760//folic acid-containing compound metabolic process;GO:0009887//organ morphogenesis;GO:0097305//response to alcohol;GO:0031960//response to corticosteroid;GO:0006206//pyrimidine nucleobase metabolic process;GO:0009117//nucleotide metabolic process;GO:0001501//skeletal system development;GO:0019087//transformation of host cell by virus;GO:0002069;GO:0048511//rhythmic process;GO:0009212//pyrimidine deoxyribonucleoside triphosphate biosynthetic process;GO:0040007//growth;GO:0009177;GO:0005975//carbohydrate metabolic process;GO:0033273//response to vitamin;GO:0006760//folic acid-containing compound metabolic process;GO:0009887//organ morphogenesis;GO:0097305//response to alcohol;GO:0031960//response to corticosteroid;GO:0006206//pyrimidine nucleobase metabolic process;GO:0009117//nucleotide metabolic process "gi|148705312|gb|EDL37259.1|/7.92385e-180/thymidylate synthase, isoform CRA_a, partial [Mus musculus]" 16168 1289.18 10.87333333 8.77 -0.310145534 Down 0.456372936 Il15 interleukin 15 K05433|1|1e-76|289|mmu:16168|interleukin 15 GO:0044424;GO:0044421;GO:0044424;GO:0044421 GO:0005102//receptor binding;GO:0005102//receptor binding GO:0001787//natural killer cell proliferation;GO:0033280//response to vitamin D;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0046633//alpha-beta T cell proliferation;GO:0008285//negative regulation of cell proliferation;GO:0021700//developmental maturation;GO:0001819//positive regulation of cytokine production;GO:0030203//glycosaminoglycan metabolic process;GO:0050688//regulation of defense response to virus;GO:0033078;GO:0002684//positive regulation of immune system process;GO:0014891//striated muscle atrophy;GO:0001779//natural killer cell differentiation;GO:0001787//natural killer cell proliferation;GO:0033280//response to vitamin D;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0046633//alpha-beta T cell proliferation;GO:0008285//negative regulation of cell proliferation;GO:0021700//developmental maturation;GO:0001819//positive regulation of cytokine production;GO:0030203//glycosaminoglycan metabolic process;GO:0050688//regulation of defense response to virus;GO:0033078;GO:0002684//positive regulation of immune system process;GO:0014891//striated muscle atrophy;GO:0001779//natural killer cell differentiation "gi|148678944|gb|EDL10891.1|/3.88658e-76/interleukin 15, isoform CRA_a, partial [Mus musculus]" 216565 4990.69 6.53 8.293333333 0.344869088 Up 0.456325924 Ehbp1 EH domain binding protein 1 K19948|1|1e-64|251|ocu:100355512|MICAL-like protein - - - gi|50510695|dbj|BAD32333.1|/0/mKIAA0903 protein [Mus musculus] 105734727 1007 2.26 1.393333333 -0.697782331 Down 0.456175486 Emc8-1190005i06rik Emc8-1190005I06Rik readthrough K06697|1|5e-11|70.9|oaa:100073774|proteasome activator subunit 2 (PA28 beta);K10733|2|5e-08|60.8|asn:102385759|GINS complex subunit 2 - - - - 60599 5392 2.283333333 3.326666667 0.542935827 Up 0.455940426 Trp53inp1 transformation related protein 53 inducible nuclear protein 1 K15310|1|6e-123|445|rno:297822|tumor protein p53-inducible nuclear protein 1 GO:0005773//vacuole;GO:0031982//vesicle;GO:0016604//nuclear body;GO:0005773//vacuole;GO:0031982//vesicle;GO:0016604//nuclear body - "GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0050896//response to stimulus;GO:0022402//cell cycle process;GO:0012502//induction of programmed cell death;GO:0006914//autophagy;GO:0016477//cell migration;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0050896//response to stimulus;GO:0022402//cell cycle process;GO:0012502//induction of programmed cell death;GO:0006914//autophagy;GO:0016477//cell migration" gi|11230806|ref|NP_068697.1|/3.15973e-123/tumor protein p53-inducible nuclear protein 1 isoform 1 [Mus musculus] 22695 1765 76.99666667 89.39 0.215317457 Up 0.455940426 Zfp36 zinc finger protein 36 K15308|1|6e-119|430|mmu:22695|tristetraprolin GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0044444//cytoplasmic part GO:0003730//mRNA 3'-UTR binding;GO:0019956//chemokine binding;GO:0019900//kinase binding GO:0006366//transcription from RNA polymerase II promoter;GO:0001817//regulation of cytokine production;GO:0048255//mRNA stabilization;GO:0030099//myeloid cell differentiation;GO:0006954//inflammatory response;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0035556//intracellular signal transduction gi|6756059|ref|NP_035886.1|/4.84667e-118/tristetraprolin [Mus musculus] 100705 8497 88.49 76.10666667 -0.217491596 Down 0.455931024 Acacb acetyl-Coenzyme A carboxylase beta K01946|1|0.0|4772|mmu:100705|acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0032550;GO:0016421//CoA carboxylase activity;GO:0043169//cation binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0019842//vitamin binding" GO:0015980//energy derivation by oxidation of organic compounds;GO:0015937//coenzyme A biosynthetic process;GO:0009893//positive regulation of metabolic process;GO:0010033//response to organic substance;GO:0003333//amino acid transmembrane transport;GO:0006637//acyl-CoA metabolic process;GO:0051260//protein homooligomerization;GO:0019217//regulation of fatty acid metabolic process gi|157042798|ref|NP_598665.2|/0/acetyl-CoA carboxylase 2 precursor [Mus musculus] 75581 1219 75.59666667 87.94666667 0.218306276 Up 0.455912219 Yipf7 "Yip1 domain family, member 7" K20363|1|2e-90|335|lcm:102356322|protein transport protein YIP1 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|12963821|ref|NP_076273.1|/8.14576e-145/protein YIPF7 [Mus musculus] 99633 6052 7.79 6.116666667 -0.348877671 Down 0.455855805 Adgrl2 adhesion G protein-coupled receptor L2 K04593|1|0.0|2921|mmu:99633|latrophilin 2 GO:0031224//intrinsic component of membrane;GO:0042995//cell projection GO:0004888//transmembrane signaling receptor activity;GO:0019904//protein domain specific binding GO:0007417//central nervous system development;GO:0007186//G-protein coupled receptor signaling pathway gi|124486821|ref|NP_001074767.1|/0/adhesion G protein-coupled receptor L2 precursor [Mus musculus] 225049 4615 6.033333333 7.7 0.351903154 Up 0.455855805 Ttc7 tetratricopeptide repeat domain 7 K09667|1|6e-07|60.1|nvi:100116809|protein O-GlcNAc transferase [EC:2.4.1.255] - - GO:0048534//hematopoietic or lymphoid organ development "gi|148706683|gb|EDL38630.1|/0/tetratricopeptide repeat domain 7, partial [Mus musculus]" 17299 887 9.706666667 11.92666667 0.297143032 Up 0.455705367 Mettl1 methyltransferase like 1 K03439|1|4e-153|542|mmu:17299|tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0016423//tRNA (guanine) methyltransferase activity GO:0001510//RNA methylation;GO:0008033//tRNA processing gi|568966859|ref|XP_006513375.1|/6.27467e-161/PREDICTED: tRNA (guanine-N(7)-)-methyltransferase isoform X1 [Mus musculus] 18628 5996.37 3.083333333 2.083333333 -0.565597176 Down 0.455498514 Per3 period circadian clock 3 K02633|1|0.0|2058|mmu:18628|period circadian protein - - - - 12332 1286.46 8.64 10.72 0.311201688 Up 0.455451503 Capg "capping protein (actin filament), gelsolin-like" "K10368|1|0.0|711|mmu:12332|capping protein (actin filament), gelsolin-like" GO:0031981//nuclear lumen;GO:0005635//nuclear envelope;GO:0048770;GO:0031981//nuclear lumen;GO:0005635//nuclear envelope;GO:0048770;GO:0031981//nuclear lumen;GO:0005635//nuclear envelope;GO:0048770;GO:0031981//nuclear lumen;GO:0005635//nuclear envelope;GO:0048770 - GO:0022607//cellular component assembly;GO:0030835//negative regulation of actin filament depolymerization;GO:0022607//cellular component assembly;GO:0030835//negative regulation of actin filament depolymerization;GO:0022607//cellular component assembly;GO:0030835//negative regulation of actin filament depolymerization;GO:0022607//cellular component assembly;GO:0030835//negative regulation of actin filament depolymerization gi|110227377|ref|NP_001035999.1|/0/macrophage-capping protein [Mus musculus] 433224 1763 0.51 1.15 1.173064709 Up 0.455432698 Gm5512 required for meiotic nuclear division 1 pseudogene K01920|1|8e-57|224|aec:105145173|glutathione synthase [EC:6.3.2.3] GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression gi|226423886|ref|NP_079619.4|/0/required for meiotic nuclear division protein 1 homolog [Mus musculus] 14086 2667 21.73 25.76333333 0.245631091 Up 0.455385686 Fscn1 fascin actin-bundling protein 1 K17455|1|0.0|966|mmu:14086|fascin 1/2 - - - - 18563 4148 14.57 17.54 0.26764787 Up 0.455329272 Pcx pyruvate carboxylase K01958|1|0.0|2152|mmu:18563|pyruvate carboxylase [EC:6.4.1.1] GO:0019866//organelle inner membrane;GO:0044429;GO:0019866//organelle inner membrane;GO:0044429 "GO:0019842//vitamin binding;GO:0016885;GO:0043169//cation binding;GO:0032550;GO:0043168//anion binding;GO:0003676//nucleic acid binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0019842//vitamin binding;GO:0016885;GO:0043169//cation binding;GO:0032550;GO:0043168//anion binding;GO:0003676//nucleic acid binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds" GO:0043648//dicarboxylic acid metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006006//glucose metabolic process;GO:0043648//dicarboxylic acid metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006006//glucose metabolic process "gi|251823978|ref|NP_032823.2|/0/pyruvate carboxylase, mitochondrial isoform 2 [Mus musculus]" 408057 2084 2.53 3.606666667 0.511528708 Up 0.455310467 BC039771 cDNA sequence BC039771 "K03847|1|4e-06|42.4|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - - 56807 3154.28 4.14 5.503333333 0.410674947 Up 0.455225845 Scamp5 secretory carrier membrane protein 5 K19995|1|7e-106|388|aml:100471204|secretory carrier-associated membrane protein GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0008021//synaptic vesicle;GO:0005802//trans-Golgi network;GO:0012505//endomembrane system;GO:0010008//endosome membrane GO:0005488//binding GO:0017156//calcium ion regulated exocytosis;GO:0033554//cellular response to stress;GO:0050663//cytokine secretion;GO:0006897//endocytosis gi|472376903|ref|XP_004407885.1|/5.22646e-109/PREDICTED: LOW QUALITY PROTEIN: secretory carrier-associated membrane protein 5 [Odobenus rosmarus divergens] 320273 1089 0.886666667 0.303333333 -1.547487795 Down 0.4550472 B230208H11Rik RIKEN cDNA B230208H11 gene - - - - - 69798 500 4.49 3.283333333 -0.451554221 Down 0.454971981 1810044D09Rik RIKEN cDNA 1810044D09 gene - - - - "gi|148666884|gb|EDK99300.1|/2.25231e-48/mCG1036982, partial [Mus musculus]" 73174 3358 10.63666667 13.02 0.291683341 Up 0.454953176 Tbkbp1 TBK1 binding protein 1 K12652|1|4e-129|465|ngi:103738324|TANK-binding kinase 1-binding protein - - - gi|880914346|ref|XP_005075961.2|/4.24147e-135/PREDICTED: TANK-binding kinase 1-binding protein 1 isoform X2 [Mesocricetus auratus] 619371 1007 1.833333333 1.043333333 -0.813268961 Down 0.454840348 Stxbp3-ps "syntaxin-binding protein 3, pseudogene" K15301|1|4e-141|503|mmu:20912|syntaxin-binding protein 3 - - - - 16154 3509 1.313333333 2.166666667 0.722244088 Up 0.454783933 Il10ra "interleukin 10 receptor, alpha" K05134|1|0.0|1033|mmu:16154|interleukin 10 receptor alpha GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424 GO:0019838//growth factor binding;GO:0019838//growth factor binding;GO:0019838//growth factor binding GO:0002237//response to molecule of bacterial origin;GO:0007166//cell surface receptor signaling pathway;GO:0002237//response to molecule of bacterial origin;GO:0007166//cell surface receptor signaling pathway;GO:0002237//response to molecule of bacterial origin;GO:0007166//cell surface receptor signaling pathway gi|6680389|ref|NP_032374.1|/0/interleukin-10 receptor subunit alpha precursor [Mus musculus] 15211 1865 39.21 45.99666667 0.230307672 Up 0.454548874 Hexa hexosaminidase A K12373|1|0.0|1062|mmu:15211|hexosaminidase [EC:3.2.1.52] GO:0000323//lytic vacuole GO:0015929//hexosaminidase activity;GO:0046983//protein dimerization activity GO:0008366//axon ensheathment;GO:0006022;GO:0050905//neuromuscular process;GO:0008344//adult locomotory behavior;GO:0050954//sensory perception of mechanical stimulus;GO:0000003//reproduction;GO:0001573//ganglioside metabolic process;GO:0010876//lipid localization;GO:0007033//vacuole organization;GO:0000904//cell morphogenesis involved in differentiation gi|67514549|ref|NP_034551.2|/0/beta-hexosaminidase subunit alpha precursor [Mus musculus] 626870 2400 0.49 1.123333333 1.196932436 Up 0.454483057 Gm11992 predicted gene 11992 - - - - gi|83776575|ref|NP_001033017.1|/1.04569e-153/uncharacterized protein C7orf57 homolog [Mus musculus] 234388 911 69.74 81 0.215935544 Up 0.454323216 Ccdc124 coiled-coil domain containing 124 - - - - gi|47059143|ref|NP_081240.1|/3.59039e-74/coiled-coil domain-containing protein 124 [Mus musculus] 75552 2305 13.99 16.9 0.272627284 Up 0.454285607 Paqr9 progestin and adipoQ receptor family member IX K17387|1|1e-08|64.7|gfr:102034408|kinesin family member 23;K07297|2|3e-08|63.5|amj:102562608|adiponectin receptor GO:0031224//intrinsic component of membrane - - gi|116089314|ref|NP_940806.2|/0/progestin and adipoQ receptor family member 9 [Mus musculus] 211389 2349 16.65666667 19.96666667 0.261493785 Up 0.454238595 Suox sulfite oxidase K00387|1|0.0|1048|mmu:211389|sulfite oxidase [EC:1.8.3.1] GO:0005740//mitochondrial envelope "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0050662//coenzyme binding;GO:0016670//oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor" GO:0031667//response to nutrient levels;GO:0044237//cellular metabolic process;GO:0044710 "gi|74024924|ref|NP_776094.2|/0/sulfite oxidase, mitochondrial precursor [Mus musculus]" 106529 1187.08 463.0733333 534.2866667 0.206373335 Up 0.454069352 Tecr "trans-2,3-enoyl-CoA reductase" K10258|1|0.0|649|mmu:106529|very-long-chain enoyl-CoA reductase [EC:1.3.1.93] GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0016491//oxidoreductase activity;GO:0016491//oxidoreductase activity GO:0000038//very long-chain fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0035336//long-chain fatty-acyl-CoA metabolic process;GO:0006641//triglyceride metabolic process;GO:0008202//steroid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0000038//very long-chain fatty acid metabolic process;GO:0008202//steroid metabolic process "gi|148678962|gb|EDL10909.1|/0/mCG11048, isoform CRA_b, partial [Mus musculus]" 14991 1425 2.31 3.346666667 0.534832012 Up 0.4538625 H2-M3 "histocompatibility 2, M region locus 3" "K06751|1|1e-179|631|mmu:14991|major histocompatibility complex, class I" GO:0009986//cell surface;GO:0042611;GO:0031224//intrinsic component of membrane GO:0005515//protein binding;GO:0003823//antigen binding GO:0045596//negative regulation of cell differentiation;GO:0045066//regulatory T cell differentiation;GO:0002517//T cell tolerance induction;GO:0002477//antigen processing and presentation of exogenous peptide antigen via MHC class Ib;GO:0006809//nitric oxide biosynthetic process;GO:0001819//positive regulation of cytokine production;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0009607//response to biotic stimulus;GO:0002286//T cell activation involved in immune response;GO:0002765//immune response-inhibiting signal transduction;GO:0006952//defense response;GO:0042098//T cell proliferation "gi|7305129|ref|NP_038847.1|/1.07366e-178/histocompatibility 2, M region locus 3 precursor [Mus musculus]" 114679 888 26.90333333 31.76666667 0.239728779 Up 0.453843695 Selm selenoprotein M - - - - - 67942 647 403.2933333 464.96 0.205277051 Up 0.45362744 Atp5g2 "ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)" K02128|1|4e-45|182|mmu:67942|F-type H+-transporting ATPase subunit c GO:0031966//mitochondrial membrane;GO:0044425 - GO:0097305//response to alcohol "gi|568993133|ref|XP_006521364.1|/3.36169e-57/PREDICTED: ATP synthase F(0) complex subunit C2, mitochondrial isoform X1 [Mus musculus]" 67993 2280 3.71 2.62 -0.501852375 Down 0.453561623 Nudt12 nudix (nucleoside diphosphate linked moiety X)-type motif 12 K03426|1|0.0|949|mmu:67993|NAD+ diphosphatase [EC:3.6.1.22] - - - - 381319 712 0.356666667 0.01 -5.156504486 Down 0.453439392 Batf3 "basic leucine zipper transcription factor, ATF-like 3" K09034|1|2e-51|204|mmu:381319|ATF-like basic leucine zipper transcriptional factor GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity "GO:0051707//response to other organism;GO:0001773//myeloid dendritic cell activation;GO:0006351//transcription, DNA-templated;GO:0002521//leukocyte differentiation" gi|47058956|ref|NP_084336.1|/1.72708e-50/basic leucine zipper transcriptional factor ATF-like 3 [Mus musculus] 11829 5088 0.766666667 0.223333333 -1.77940086 Down 0.453100906 Aqp4 aquaporin 4 K09866|1|7e-164|581|mmu:11829|aquaporin-4 - - - - 211623 484 19.47666667 16.23333333 -0.262787517 Down 0.453053894 Plac9a placenta specific 9a - - - - gi|74203396|dbj|BAE20859.1|/7.43482e-30/unnamed protein product [Mus musculus] 75668 1108 3.293333333 2.27 -0.536856244 Down 0.452856444 Rasl10a "RAS-like, family 10, member A" K07850|1|5e-117|423|mmu:75668|Ras-like protein family member 10A GO:0031981//nuclear lumen;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process gi|21644573|ref|NP_660251.1|/4.02857e-116/ras-like protein family member 10A precursor [Mus musculus] 21763 4947 14.62666667 12.08 -0.27598057 Down 0.45283764 Tex2 testis expressed gene 2 K02602|1|5e-24|117|dya:Dyak_GE21274|cytoplasmic polyadenylation element-binding protein;K12884|3|3e-16|91.3|cge:100753025|heterogeneous nuclear ribonucleoprotein C1/C2 - - - gi|46430497|ref|NP_938034.2|/0/testis-expressed sequence 2 protein [Mus musculus] 381175 1525 1.32 0.65 -1.022026306 Down 0.452724811 Ccdc68 coiled-coil domain containing 68 - - - - "gi|148677642|gb|EDL09589.1|/2.09555e-159/coiled-coil domain containing 68, isoform CRA_b, partial [Mus musculus]" 231861 9601.02 9.326666667 7.446666667 -0.324766777 Down 0.452649592 Tnrc18 trinucleotide repeat containing 18 - - GO:0003676//nucleic acid binding - gi|402232746|ref|NP_001116202.2|/0/trinucleotide repeat-containing gene 18 protein isoform A [Mus musculus] 66647 1391 9.106666667 11.24333333 0.304074835 Up 0.452630787 Ndnl2 necdin-like 2 K12464|1|2e-48|195|tup:102484167|melanoma-associated antigen D1 GO:0043231//intracellular membrane-bounded organelle;GO:0000793//condensed chromosome GO:0005488//binding "GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0040007//growth;GO:0016567//protein ubiquitination;GO:0006351//transcription, DNA-templated" gi|47847470|dbj|BAD21407.1|/1.01206e-149/mFLJ00211 protein [Mus musculus] 11764 4123.81 30.15666667 25.46 -0.244244552 Down 0.452574373 Ap1b1 "adaptor protein complex AP-1, beta 1 subunit" K12392|1|0.0|1665|mmu:11764|AP-1 complex subunit beta-1 GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0030119//AP-type membrane coat adaptor complex GO:0022892//substrate-specific transporter activity GO:0006901//vesicle coating;GO:0015031//protein transport gi|339895916|ref|NP_001229973.1|/0/AP-1 complex subunit beta-1 isoform 3 [Mus musculus] 74580 3119 0.716666667 0.19 -1.915302835 Down 0.452470947 Pyroxd2 pyridine nucleotide-disulphide oxidoreductase domain 2 "K00280|1|0.0|736|cjo:107316034|lysyl oxidase-like protein 2/3/4 [EC:1.4.3.-];K09516|3|1e-10|72.0|mmu:67442|all-trans-retinol 13,14-reductase [EC:1.3.99.23]" - - - gi|125858598|ref|NP_083287.2|/0/pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 [Mus musculus] 27402 2527 72.58 62.38333333 -0.218411414 Down 0.452433337 Pdhx "pyruvate dehydrogenase complex, component X" K13997|1|0.0|853|mmu:27402|dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex GO:0044429 GO:0016740//transferase activity GO:0006086//acetyl-CoA biosynthetic process from pyruvate "gi|28201978|ref|NP_780303.1|/0/pyruvate dehydrogenase protein X component, mitochondrial [Mus musculus]" 13593 4981.96 3.84 2.74 -0.486930418 Down 0.452273497 Ebf3 early B cell factor 3 K09103|1|0.0|1092|ocu:100344272|early B-cell factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0005515//protein binding;GO:0043169//cation binding;GO:0005515//protein binding;GO:0043169//cation binding;GO:0005515//protein binding "GO:0006351//transcription, DNA-templated;GO:0032502//developmental process;GO:0006351//transcription, DNA-templated;GO:0032502//developmental process;GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|157817660|ref|NP_001101976.1|/0/transcription factor COE3 [Rattus norvegicus] 67442 1942 37.14666667 43.45333333 0.226234094 Up 0.452254692 Retsat "retinol saturase (all trans retinol 13,14 reductase)" "K09516|1|0.0|1116|mmu:67442|all-trans-retinol 13,14-reductase [EC:1.3.99.23]" GO:0031965//nuclear membrane "GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors" GO:0001523//retinoid metabolic process "gi|52627143|ref|NP_080435.3|/0/all-trans-retinol 13,14-reductase precursor [Mus musculus]" 545548 623 0.87 0.296666667 -1.552172566 Down 0.452000827 Lce3a late cornified envelope 3A - - - - - 19039 2168 60.01333333 69.89666667 0.219940592 Up 0.451850389 Lgals3bp "lectin, galactoside-binding, soluble, 3 binding protein" K17300|1|0.0|1154|mmu:19039|galectin-3-binding protein GO:0031988//membrane-bounded vesicle;GO:0031012//extracellular matrix GO:0005488//binding;GO:0038024//cargo receptor activity GO:0022610 gi|6755144|ref|NP_035280.1|/0/galectin-3-binding protein precursor [Mus musculus] 12336 1461 247.53 285.6733333 0.206762985 Up 0.451746963 Capns1 "calpain, small subunit 1" "K08583|1|5e-115|417|mmu:12336|calpain, small subunit 1" GO:0016020//membrane;GO:0044424 GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0004197//cysteine-type endopeptidase activity GO:0019538//protein metabolic process;GO:0008283//cell proliferation gi|110227381|ref|NP_033925.2|/4.30836e-114/calpain small subunit 1 [Mus musculus] 382245 1333.68 0.373333333 0.966666667 1.372554168 Up 0.451662342 Tmem29 transmembrane protein 29 - - - - gi|564322584|ref|XP_003754798.2|/1.02028e-60/PREDICTED: protein FAM104A-like isoform X2 [Rattus norvegicus] 57815 3255.08 3.45 2.41 -0.517563215 Down 0.451521306 Spata5 spermatogenesis associated 5 K14575|1|0.0|1679|mmu:57815|AAA family ATPase - - - gi|254553470|ref|NP_001156983.1|/0/spermatogenesis-associated protein 5 isoform 1 [Mus musculus] 20229 1198.85 20.22 23.96333333 0.245045606 Up 0.451446087 Sat1 spermidine/spermine N1-acetyl transferase 1 K00657|1|1e-97|358|mmu:20229|diamine N-acetyltransferase [EC:2.3.1.57] GO:0044424;GO:0044424 GO:0008080//N-acetyltransferase activity;GO:0019808//polyamine binding;GO:0008080//N-acetyltransferase activity;GO:0019808//polyamine binding GO:0048646//anatomical structure formation involved in morphogenesis;GO:0008283//cell proliferation;GO:0006598//polyamine catabolic process;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0008283//cell proliferation;GO:0006598//polyamine catabolic process gi|33086594|gb|AAP92609.1|/3.55476e-97/Ab2-402 [Rattus norvegicus] 14178 2672 0.333333333 0.913333333 1.454175893 Up 0.451427282 Fgf7 fibroblast growth factor 7 K04358|1|1e-99|367|mmu:14178|fibroblast growth factor GO:0043231//intracellular membrane-bounded organelle;GO:0044421 GO:0005539//glycosaminoglycan binding;GO:0005104//fibroblast growth factor receptor binding GO:0001934//positive regulation of protein phosphorylation;GO:0009611//response to wounding;GO:0034613//cellular protein localization;GO:0001942//hair follicle development;GO:0046165;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030323//respiratory tube development;GO:0006935//chemotaxis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0048875//chemical homeostasis within a tissue;GO:0006644//phospholipid metabolic process;GO:0030335//positive regulation of cell migration;GO:0060638//mesenchymal-epithelial cell signaling;GO:0007435//salivary gland morphogenesis;GO:0032940//secretion by cell gi|537151192|gb|ERE71530.1|/1.85366e-114/keratinocyte growth factor-like protein [Cricetulus griseus] 84113 1897 57.97666667 67.58333333 0.22119512 Up 0.451408477 Ptov1 prostate tumor over expressed gene 1 K15168|1|1e-67|260|myb:102243510|mediator of RNA polymerase II transcription subunit 25 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane - "GO:0006351//transcription, DNA-templated" "gi|148690819|gb|EDL22766.1|/0/prostate tumor over expressed gene 1, isoform CRA_b, partial [Mus musculus]" 319830 3629 0.96 1.72 0.841302254 Up 0.451352063 1500004A13Rik RIKEN cDNA 1500004A13 gene K15196|1|3e-10|70.5|mze:101481634|transcription factor IIIB 90 kDa subunit - - - - 30924 1609 1.106666667 1.896666667 0.777245411 Up 0.451107601 Angptl3 angiopoietin-like 3 K08767|1|8e-75|283|fab:101819845|angiopoietin-like 4 - - - - 213350 1497 6.286666667 7.953333333 0.339264367 Up 0.451041784 Pddc1 Parkinson disease 7 domain containing 1 - - - - gi|26353102|dbj|BAC40181.1|/7.139e-133/unnamed protein product [Mus musculus] 19672 3063 8.16 10.14 0.313416595 Up 0.450881944 Rcn1 reticulocalbin 1 K19934|1|8e-34|148|sko:100368121|calcium-binding protein GO:0044432 GO:0046872//metal ion binding GO:0043009//chordate embryonic development;GO:0001654//eye development gi|6677691|ref|NP_033063.1|/9.58005e-179/reticulocalbin-1 precursor [Mus musculus] 26371 3075 15.82333333 18.94666667 0.259890505 Up 0.450816127 Ciao1 cytosolic iron-sulfur protein assembly 1 K04508|1|6e-24|115|ola:101165003|transducin (beta)-like 1 GO:0005819//spindle - GO:0044763;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter gi|31542399|ref|NP_079572.2|/0/probable cytosolic iron-sulfur protein assembly protein CIAO1 [Mus musculus] 211945 6451 2.426666667 1.55 -0.646707734 Down 0.45078792 Plekhh1 "pleckstrin homology domain containing, family H (with MyTH4 domain) member 1" K10359|1|1e-33|149|aqu:100639733|myosin VII;K12559|3|2e-31|142|mze:101480403|myosin X - - - gi|28972660|dbj|BAC65746.1|/0/mKIAA1200 protein [Mus musculus] 71817 1117 55.47333333 64.77666667 0.223679813 Up 0.450759713 Tmem50a transmembrane protein 50A - GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - - gi|34610239|ref|NP_082211.1|/4.70308e-88/transmembrane protein 50A [Mus musculus] 23992 1554 9.173333333 7.333333333 -0.322976946 Down 0.450740908 Prkra "protein kinase, interferon inducible double stranded RNA dependent activator" K18420|1|3e-145|517|mdo:100026897|RISC-loading complex subunit TARBP2 GO:0044444//cytoplasmic part "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0003723//RNA binding;GO:0042802//identical protein binding;GO:0030234//enzyme regulator activity" GO:0012502//induction of programmed cell death;GO:0051707//response to other organism;GO:0042471//ear morphogenesis;GO:0006464//cellular protein modification process;GO:0001501//skeletal system development;GO:0044093;GO:0002376//immune system process;GO:0006796//phosphate-containing compound metabolic process;GO:0008283//cell proliferation;GO:0016246//RNA interference gi|6755162|ref|NP_036001.1|/8.38727e-180/interferon-inducible double-stranded RNA-dependent protein kinase activator A [Mus musculus] 66090 978.17 56.06 65.34333333 0.221068308 Up 0.450712701 Ypel3 yippee-like 3 (Drosophila) K04371|1|8e-08|60.5|asn:102375250|mitogen-activated protein kinase 1/3 [EC:2.7.11.24] - - - "gi|148685489|gb|EDL17436.1|/1.63487e-79/yippee-like 3 (Drosophila), isoform CRA_c [Mus musculus]" 67564 1979 2.6 3.673333333 0.498578195 Up 0.450675091 Tmem35 transmembrane protein 35A - GO:0044439;GO:0031982//vesicle;GO:0031224//intrinsic component of membrane - - gi|444518831|gb|ELV12416.1|/2.38125e-76/Transmembrane protein 35 [Tupaia chinensis] 212390 2385.99 0.72 1.423333333 0.983204757 Up 0.450628079 Klhl32 kelch-like 32 K10468|1|0.0|1261|rno:313111|kelch-like protein 32 - - - gi|247301129|ref|NP_001028703.2|/0/kelch-like protein 32 isoform 2 [Mus musculus] 99371 8777 10.31 8.34 -0.305925044 Down 0.450411824 Arfgef2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) K18442|1|0.0|3468|mmu:99371|brefeldin A-inhibited guanine nucleotide-exchange protein - - - gi|148229140|ref|NP_001078964.1|/0/brefeldin A-inhibited guanine nucleotide-exchange protein 2 [Mus musculus] 68652 4278 22.77 19.10333333 -0.253309896 Down 0.450402422 Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 K04404|1|0.0|1354|mmu:68652|TAK1-binding protein 2 GO:0043231//intracellular membrane-bounded organelle GO:0031593//polyubiquitin binding;GO:0046914//transition metal ion binding GO:0044767//single-organism developmental process;GO:0001934//positive regulation of protein phosphorylation gi|20149752|ref|NP_619608.1|/0/TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [Mus musculus] 380714 2122.24 4.996666667 3.743333333 -0.416642456 Down 0.450110948 Rph3al rabphilin 3A-like (without C2 domains) K19939|1|1e-160|569|mmu:380714|Rab effector Noc2 GO:0030141//secretory granule;GO:0030133//transport vesicle;GO:0030141//secretory granule;GO:0030133//transport vesicle GO:0017016//Ras GTPase binding;GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding;GO:0017016//Ras GTPase binding;GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding GO:0009306//protein secretion;GO:0017156//calcium ion regulated exocytosis;GO:0042221//response to chemical;GO:0007186//G-protein coupled receptor signaling pathway;GO:0033500//carbohydrate homeostasis;GO:0009306//protein secretion;GO:0017156//calcium ion regulated exocytosis;GO:0042221//response to chemical;GO:0007186//G-protein coupled receptor signaling pathway;GO:0033500//carbohydrate homeostasis gi|599044454|ref|NP_001278088.1|/4.85491e-75/rab effector Noc2 isoform 2 [Mus musculus] 52132 2986 34.53 40.41 0.226862017 Up 0.449932303 Ccdc97 coiled-coil domain containing 97 - - - - gi|21311899|ref|NP_083047.1|/3.83204e-140/coiled-coil domain-containing protein 97 [Mus musculus] 78926 2731.21 12.18333333 9.943333333 -0.293107429 Down 0.449894693 Gas2l1 growth arrest-specific 2 like 1 K10382|1|9e-16|88.6|crg:105323136|dystonin GO:0032432//actin filament bundle;GO:0015630//microtubule cytoskeleton;GO:0032432//actin filament bundle;GO:0015630//microtubule cytoskeleton;GO:0032432//actin filament bundle;GO:0015630//microtubule cytoskeleton;GO:0032432//actin filament bundle;GO:0015630//microtubule cytoskeleton "GO:0030674//protein binding, bridging;GO:0015631//tubulin binding;GO:0008134//transcription factor binding;GO:0030674//protein binding, bridging;GO:0015631//tubulin binding;GO:0008134//transcription factor binding;GO:0030674//protein binding, bridging;GO:0015631//tubulin binding;GO:0008134//transcription factor binding;GO:0030674//protein binding, bridging;GO:0015631//tubulin binding;GO:0008134//transcription factor binding" GO:0010467//gene expression;GO:0022402//cell cycle process;GO:0030218//erythrocyte differentiation;GO:0007019//microtubule depolymerization;GO:0033554//cellular response to stress;GO:0016049//cell growth;GO:0032870//cellular response to hormone stimulus;GO:0010467//gene expression;GO:0022402//cell cycle process;GO:0030218//erythrocyte differentiation;GO:0007019//microtubule depolymerization;GO:0033554//cellular response to stress;GO:0016049//cell growth;GO:0032870//cellular response to hormone stimulus;GO:0010467//gene expression;GO:0022402//cell cycle process;GO:0030218//erythrocyte differentiation;GO:0007019//microtubule depolymerization;GO:0033554//cellular response to stress;GO:0016049//cell growth;GO:0032870//cellular response to hormone stimulus;GO:0010467//gene expression;GO:0022402//cell cycle process;GO:0030218//erythrocyte differentiation;GO:0007019//microtubule depolymerization;GO:0033554//cellular response to stress;GO:0016049//cell growth;GO:0032870//cellular response to hormone stimulus gi|298676484|ref|NP_084504.2|/1.43674e-145/GAS2-like protein 1 isoform alpha [Mus musculus] 101521 2373 0.216666667 0.743333333 1.778532087 Up 0.449847681 AI314278 expressed sequence AI314278 - - - - "gi|148674839|gb|EDL06786.1|/4.05409e-41/mCG1028300, isoform CRA_a, partial [Mus musculus]" 19087 4041 23.22666667 19.59666667 -0.245173846 Down 0.449838279 Prkar2a "protein kinase, cAMP dependent regulatory, type II alpha" K04739|1|0.0|733|mmu:19087|cAMP-dependent protein kinase regulator GO:0005815//microtubule organizing center;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0042383//sarcolemma "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0051018//protein kinase A binding;GO:0030551//cyclic nucleotide binding;GO:0042802//identical protein binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0019887//protein kinase regulator activity" GO:0001932//regulation of protein phosphorylation;GO:0051259//protein oligomerization;GO:0010243//response to organonitrogen compound;GO:0007154//cell communication gi|22550094|ref|NP_032950.1|/0/cAMP-dependent protein kinase type II-alpha regulatory subunit [Mus musculus] 17357 1611 2.69 3.766666667 0.485682194 Up 0.449800669 Marcksl1 MARCKS-like 1 K13536|1|4e-56|221|mmu:17357|MARCKS-related protein GO:0016020//membrane - GO:0006810//transport;GO:0008283//cell proliferation gi|672013322|ref|XP_008772695.1|/3.44494e-83/PREDICTED: MARCKS-related protein-like [Rattus norvegicus] 544678 2554.86 0.57 1.21 1.085973223 Up 0.449772462 Cfap74 cilia and flagella associated protein 74 K10388|1|7e-11|72.4|lcm:102349027|plectin;K18626|3|4e-09|66.6|umr:103667492|trichohyalin - - - gi|74147924|dbj|BAE22316.1|/0/unnamed protein product [Mus musculus] 26425 2139 4.686666667 6.096666667 0.379458481 Up 0.449640829 Nubp1 nucleotide binding protein 1 K03593|1|9e-42|174|dre:436715|ATP-binding protein involved in chromosome partitioning GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0016462//pyrophosphatase activity;GO:0032550 GO:0009058//biosynthetic process;GO:0040007//growth;GO:0006875//cellular metal ion homeostasis gi|6754906|ref|NP_036085.1|/4.49e-177/cytosolic Fe-S cluster assembly factor NUBP1 [Mus musculus] 110391 1394 34.12 39.94333333 0.227337086 Up 0.449575012 Qdpr quinoid dihydropteridine reductase K00357|1|2e-118|428|mmu:110391|dihydropteridine reductase [EC:1.5.1.34] GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0044444//cytoplasmic part "GO:0043168//anion binding;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding" GO:0006558//L-phenylalanine metabolic process;GO:0010038//response to metal ion;GO:0009108//coenzyme biosynthetic process;GO:0042558//pteridine-containing compound metabolic process;GO:0044767//single-organism developmental process;GO:0043434//response to peptide hormone;GO:0042493//response to drug "gi|149047261|gb|EDL99930.1|/5.2506e-122/quinoid dihydropteridine reductase, isoform CRA_a [Rattus norvegicus]" 79201 3305 1.423333333 2.273333333 0.675535669 Up 0.449546805 Tnfrsf23 "tumor necrosis factor receptor superfamily, member 23" K05159|1|3e-88|329|mmu:79201|tumor necrosis factor receptor superfamily member 23;K05158|2|2e-66|256|mmu:79202|tumor necrosis factor receptor superfamily member 22;K04722|4|2e-19|100|mze:101465040|tumor necrosis factor receptor superfamily member 10 - - - - 66055 1133 13.17 15.87333333 0.269349774 Up 0.449518598 Sf3b6 "splicing factor 3B, subunit 6" K12833|1|8e-59|229|lcm:102363321|pre-mRNA branch site protein p14 GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen GO:0036094//small molecule binding;GO:0003676//nucleic acid binding GO:0000377 gi|966711066|gb|KTG43304.1|/6.76839e-58/hypothetical protein cypCar_00025924 [Cyprinus carpio] 23991 1055 6.803333333 8.546666667 0.32912008 Up 0.449499793 Cib1 calcium and integrin binding 1 (calmyrin) K17259|1|9e-57|222|cge:100772612|calcium and integrin-binding protein 1 GO:0031981//nuclear lumen;GO:0044459;GO:0042995//cell projection;GO:0031981//nuclear lumen;GO:0044459;GO:0042995//cell projection;GO:0031981//nuclear lumen;GO:0005886//plasma membrane GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding GO:0000278//mitotic cell cycle;GO:0012501//programmed cell death;GO:0033554//cellular response to stress;GO:0007166//cell surface receptor signaling pathway;GO:0033173//calcineurin-NFAT signaling cascade;GO:0051130//positive regulation of cellular component organization;GO:0008283//cell proliferation;GO:0000278//mitotic cell cycle;GO:0012501//programmed cell death;GO:0033554//cellular response to stress;GO:0007166//cell surface receptor signaling pathway;GO:0033173//calcineurin-NFAT signaling cascade;GO:0051130//positive regulation of cellular component organization;GO:0008283//cell proliferation;GO:0000278//mitotic cell cycle;GO:0012501//programmed cell death;GO:0033554//cellular response to stress;GO:0007166//cell surface receptor signaling pathway;GO:0033173//calcineurin-NFAT signaling cascade;GO:0051130//positive regulation of cellular component organization;GO:0008283//cell proliferation gi|602617449|ref|NP_001278204.1|/2.08489e-87/calcium and integrin-binding protein 1 isoform 2 [Mus musculus] 217893 5481.19 18.34333333 15.28 -0.263611285 Down 0.449490391 Pacs2 phosphofurin acidic cluster sorting protein 2 K16537|1|8e-16|89.7|oaa:100077400|pericentriolar material 1 protein - - - - 319660 2155 2.6 1.696666667 -0.615808468 Down 0.449358757 Agmo alkylglycerol monooxygenase K15537|1|0.0|857|mmu:319660|alkylglycerol monooxygenase [EC:1.14.16.5] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0046914//transition metal ion binding;GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen" GO:0006631//fatty acid metabolic process;GO:0018904 gi|148540116|ref|NP_848882.2|/0/alkylglycerol monooxygenase [Mus musculus] 76303 4590 39.17666667 33.39333333 -0.230434541 Down 0.449349355 Osbp oxysterol binding protein K20456|1|0.0|1398|mmu:76303|oxysterol-binding protein 1 GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle GO:0032934//sterol binding GO:0010876//lipid localization;GO:0051234//establishment of localization "gi|148709509|gb|EDL41455.1|/0/mCG22485, partial [Mus musculus]" 72690 1255 8 9.946666667 0.31421313 Up 0.449339953 Grrp1 glycine/arginine rich protein 1 K00685|1|4e-104|380|tup:102482899|arginine-tRNA-protein transferase [EC:2.3.2.8] - - - gi|568931936|ref|XP_006539260.1|/7.87558e-151/PREDICTED: protein FAM110D isoform X2 [Mus musculus] 14857 861 2.823333333 1.893333333 -0.57647104 Down 0.449245929 Gsta1 "glutathione S-transferase, alpha 1 (Ya)" K00799|1|2e-123|444|mmu:14857|glutathione S-transferase [EC:2.5.1.18] GO:0031965//nuclear membrane;GO:0044444//cytoplasmic part "GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0072341//modified amino acid binding" GO:0006805//xenobiotic metabolic process;GO:0044767//single-organism developmental process gi|154350202|ref|NP_032207.3|/1.44607e-122/glutathione S-transferase A1 [Mus musculus] 21428 1907.95 11.38333333 13.81333333 0.279138425 Up 0.449217722 Mlx MAX-like protein X K09113|1|3e-152|541|mmu:21428|MAX-like protein X GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity "GO:0009893//positive regulation of metabolic process;GO:0015980//energy derivation by oxidation of organic compounds;GO:0051169//nuclear transport;GO:0006351//transcription, DNA-templated;GO:0009893//positive regulation of metabolic process;GO:0015980//energy derivation by oxidation of organic compounds;GO:0051169//nuclear transport;GO:0006351//transcription, DNA-templated;GO:0009893//positive regulation of metabolic process;GO:0015980//energy derivation by oxidation of organic compounds;GO:0051169//nuclear transport;GO:0006351//transcription, DNA-templated" gi|829945377|ref|XP_012598651.1|/4.42727e-138/PREDICTED: max-like protein X isoform X1 [Microcebus murinus] 74596 3939 2.076666667 1.26 -0.720845929 Down 0.4491331 Cds1 CDP-diacylglycerol synthase 1 K00981|1|0.0|859|mmu:74596|phosphatidate cytidylyltransferase [EC:2.7.7.41] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0017169//CDP-alcohol phosphatidyltransferase activity;GO:0070567 GO:0046341//CDP-diacylglycerol metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0007165//signal transduction gi|33186923|ref|NP_775546.2|/0/phosphatidate cytidylyltransferase 1 [Mus musculus] 319166 558 0.156666667 0.656666667 2.067462968 Up 0.449123698 Hist1h2ae "histone cluster 1, H2ae" K11251|1|8e-54|211|ecb:100053897|histone H2A - - - - 192287 3061 5.716666667 4.356666667 -0.391949435 Down 0.449067283 Slc25a36 "solute carrier family 25, member 36" "K15116|1|7e-174|613|mmu:192287|solute carrier family 25, member 33/36" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763;GO:0043627//response to estrogen gi|20270293|ref|NP_620095.1|/6.00757e-173/solute carrier family 25 member 36 [Mus musculus] 66175 1194 15.80333333 13.12 -0.268461172 Down 0.44897326 Mustn1 "musculoskeletal, embryonic nuclear protein 1" - GO:0031981//nuclear lumen - GO:0009611//response to wounding;GO:0035108//limb morphogenesis;GO:0009888//tissue development "gi|148692820|gb|EDL24767.1|/5.41252e-53/musculoskeletal, embryonic nuclear protein 1, partial [Mus musculus]" 109042 1026 28.49333333 24.16 -0.238003953 Down 0.448916845 Prkcdbp "protein kinase C, delta binding protein" K19387|1|7e-14|80.5|shr:100933321|polymerase I and transcript release factor - - - - 218885 2062 39.14666667 33.44666667 -0.22702703 Down 0.448879236 Oxnad1 oxidoreductase NAD-binding domain containing 1 K00326|1|3e-07|59.7|tca:660758|cytochrome-b5 reductase [EC:1.6.2.2] GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity GO:0044710 "gi|148692881|gb|EDL24828.1|/0/oxidoreductase NAD-binding domain containing 1, isoform CRA_c [Mus musculus]" 67125 1543 52 60.46666667 0.217628427 Up 0.448681786 Tspan31 tetraspanin 31 K17356|1|7e-96|353|mmu:67125|tetraspanin-13/31 GO:0031224//intrinsic component of membrane - - gi|13385482|ref|NP_080258.1|/6.29743e-95/tetraspanin-31 [Mus musculus] 107746 6127.33 58.62 50.23 -0.222843693 Down 0.44850314 Rapgef1 Rap guanine nucleotide exchange factor (GEF) 1 K06277|1|0.0|1906|cge:100764804|Rap guanine nucleotide exchange factor 1 - "GO:0060089;GO:0030674//protein binding, bridging;GO:0030695//GTPase regulator activity" GO:0019222//regulation of metabolic process;GO:0007155//cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|84875504|ref|NP_001034175.1|/0/rap guanine nucleotide exchange factor 1 isoform 2 [Mus musculus] 20848 4515.01 58.72333333 50.35666667 -0.221751075 Down 0.448465531 Stat3 signal transducer and activator of transcription 3 K04692|1|0.0|1508|myb:102239853|signal transducer and activator of transcription 3 - - - - 12038 6209 2.743333333 1.823333333 -0.589351598 Down 0.448409117 Bche butyrylcholinesterase K01050|1|0.0|1258|mmu:12038|cholinesterase [EC:3.1.1.8] GO:0044432;GO:0005635//nuclear envelope;GO:0044421 GO:0043169//cation binding;GO:0004104//cholinesterase activity GO:0010243//response to organonitrogen compound;GO:0031667//response to nutrient levels;GO:0007611//learning or memory;GO:0030154//cell differentiation;GO:0007268//chemical synaptic transmission;GO:0031960//response to corticosteroid;GO:0042439//ethanolamine-containing compound metabolic process;GO:0008283//cell proliferation gi|755503274|ref|XP_011238302.1|/0/PREDICTED: cholinesterase isoform X1 [Mus musculus] 70207 1351 38.49 32.86 -0.228151191 Down 0.448352702 Taco1 translational activator of mitochondrially encoded cytochrome c oxidase I K18189|1|2e-151|538|mmu:70207|translational activator of cytochrome c oxidase 1 GO:0043231//intracellular membrane-bounded organelle - GO:0006412//translation gi|39930435|ref|NP_081622.1|/1.50635e-150/translational activator of cytochrome c oxidase 1 [Mus musculus] 12827 6467 166.2433333 144.05 -0.206726827 Down 0.448315093 Col4a2 "collagen, type IV, alpha 2" "K06237|1|0.0|2370|mmu:12827|collagen, type IV, alpha" - - - - 67170 1074 4.106666667 5.416666667 0.399437462 Up 0.448230471 2610306M01Rik RIKEN cDNA 2610306M01 gene - - - - - 11625 1503 2.896666667 4.006666667 0.468008814 Up 0.448221069 Ahsg alpha-2-HS-glycoprotein K03898|1|4e-07|58.9|mgp:104912678|kininogen GO:0032991//macromolecular complex;GO:0044421;GO:0032991//macromolecular complex;GO:0044421;GO:0032991//macromolecular complex;GO:0044421;GO:0032991//macromolecular complex;GO:0044421 GO:0030292//protein tyrosine kinase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0030292//protein tyrosine kinase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0030292//protein tyrosine kinase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0030292//protein tyrosine kinase inhibitor activity;GO:0004866//endopeptidase inhibitor activity GO:0006909//phagocytosis;GO:0032846;GO:0008286//insulin receptor signaling pathway;GO:0002526//acute inflammatory response;GO:0030279//negative regulation of ossification;GO:0016310//phosphorylation;GO:0008406//gonad development;GO:0021543//pallium development;GO:0065003;GO:0009887//organ morphogenesis;GO:0016049//cell growth;GO:0006909//phagocytosis;GO:0032846;GO:0008286//insulin receptor signaling pathway;GO:0002526//acute inflammatory response;GO:0030279//negative regulation of ossification;GO:0016310//phosphorylation;GO:0008406//gonad development;GO:0021543//pallium development;GO:0065003;GO:0009887//organ morphogenesis;GO:0016049//cell growth;GO:0006909//phagocytosis;GO:0032846;GO:0008286//insulin receptor signaling pathway;GO:0002526//acute inflammatory response;GO:0030279//negative regulation of ossification;GO:0016310//phosphorylation;GO:0008406//gonad development;GO:0021543//pallium development;GO:0065003;GO:0009887//organ morphogenesis;GO:0016049//cell growth;GO:0006909//phagocytosis;GO:0032846;GO:0008286//insulin receptor signaling pathway;GO:0002526//acute inflammatory response;GO:0030279//negative regulation of ossification;GO:0016310//phosphorylation;GO:0008406//gonad development;GO:0021543//pallium development;GO:0065003;GO:0009887//organ morphogenesis;GO:0016049//cell growth gi|7304875|ref|NP_038493.1|/4.87638e-167/alpha-2-HS-glycoprotein isoform 1 precursor [Mus musculus] 100038746 1855 0.516666667 1.14 1.14172811 Up 0.448221069 Gm1976 predicted gene 1976 K09228|1|2e-06|56.6|mmu:235956|KRAB domain-containing zinc finger protein - - - gi|26349855|dbj|BAC38567.1|/9.3153e-54/unnamed protein product [Mus musculus] 50909 2762 11.20333333 13.60666667 0.28038564 Up 0.448211666 C1ra "complement component 1, r subcomponent A" "K01330|1|0.0|1509|mmu:50909|complement component 1, r subcomponent [EC:3.4.21.41]" - GO:0046872//metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0006952//defense response;GO:0002455//humoral immune response mediated by circulating immunoglobulin gi|164518925|ref|NP_075632.3|/0/complement C1r-A subcomponent precursor [Mus musculus] 17850 3675 22.49333333 18.97333333 -0.245524312 Down 0.447967204 Mut methylmalonyl-Coenzyme A mutase K01847|1|0.0|1437|rno:688517|methylmalonyl-CoA mutase [EC:5.4.99.2] GO:0043231//intracellular membrane-bounded organelle GO:0016866//intramolecular transferase activity;GO:0043169//cation binding;GO:0019842//vitamin binding;GO:0016597//amino acid binding GO:0007275//multicellular organism development;GO:0000096//sulfur amino acid metabolic process "gi|672023790|ref|XP_003754543.2|/0/PREDICTED: methylmalonyl-CoA mutase, mitochondrial [Rattus norvegicus]" 12575 1913 133.0633333 154.2533333 0.213188586 Up 0.44791079 Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) K06625|1|8e-90|333|mmu:12575|cyclin-dependent kinase inhibitor 1A - - - - 13819 5352 154.2133333 133.1666667 -0.211694504 Down 0.447901388 Epas1 endothelial PAS domain protein 1 K09095|1|0.0|1620|mmu:13819|hypoxia-inducible factor 2 alpha GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0019899//enzyme binding GO:0048771//tissue remodeling;GO:0006366//transcription from RNA polymerase II promoter;GO:0008016//regulation of heart contraction;GO:0006584//catecholamine metabolic process;GO:0045165//cell fate commitment;GO:0050953//sensory perception of light stimulus;GO:0021700//developmental maturation;GO:0007154//cell communication;GO:0006996//organelle organization;GO:0030099//myeloid cell differentiation;GO:0030323//respiratory tube development;GO:0048875//chemical homeostasis within a tissue;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0034599//cellular response to oxidative stress;GO:0001701//in utero embryonic development gi|178057356|ref|NP_034267.3|/0/endothelial PAS domain-containing protein 1 [Mus musculus] 71971 2721 3.486666667 4.686666667 0.426713743 Up 0.447863778 Zswim1 zinc finger SWIM-type containing 1 K17604|1|7e-53|211|cmy:102943223|zinc finger SWIM domain-containing protein 3 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - "gi|148674477|gb|EDL06424.1|/0/zinc finger, SWIM domain containing 1, isoform CRA_a, partial [Mus musculus]" 67528 1155.06 50.14 58.28333333 0.217121394 Up 0.447844973 Nudt7 nudix (nucleoside diphosphate linked moiety X)-type motif 7 K17879|1|1e-126|457|mmu:67528|peroxisomal coenzyme A diphosphatase NUDT7 [EC:3.6.1.-] GO:0042579//microbody;GO:0042579//microbody;GO:0042579//microbody;GO:0042579//microbody;GO:0042579//microbody GO:0046914//transition metal ion binding;GO:0016289//CoA hydrolase activity;GO:0005515//protein binding;GO:0016462//pyrophosphatase activity;GO:0046914//transition metal ion binding;GO:0016289//CoA hydrolase activity;GO:0005515//protein binding;GO:0016462//pyrophosphatase activity;GO:0046914//transition metal ion binding;GO:0016289//CoA hydrolase activity;GO:0005515//protein binding;GO:0016462//pyrophosphatase activity;GO:0046914//transition metal ion binding;GO:0016289//CoA hydrolase activity;GO:0005515//protein binding;GO:0016462//pyrophosphatase activity;GO:0046914//transition metal ion binding;GO:0016289//CoA hydrolase activity;GO:0005515//protein binding;GO:0016462//pyrophosphatase activity GO:0006084//acetyl-CoA metabolic process;GO:0006753//nucleoside phosphate metabolic process;GO:0009109;GO:0045444//fat cell differentiation;GO:0006084//acetyl-CoA metabolic process;GO:0006753//nucleoside phosphate metabolic process;GO:0009109;GO:0045444//fat cell differentiation;GO:0006084//acetyl-CoA metabolic process;GO:0006753//nucleoside phosphate metabolic process;GO:0009109;GO:0045444//fat cell differentiation;GO:0006084//acetyl-CoA metabolic process;GO:0006753//nucleoside phosphate metabolic process;GO:0009109;GO:0045444//fat cell differentiation;GO:0006084//acetyl-CoA metabolic process;GO:0006753//nucleoside phosphate metabolic process;GO:0009109;GO:0045444//fat cell differentiation gi|589269111|ref|NP_001277111.1|/1.58403e-95/peroxisomal coenzyme A diphosphatase NUDT7 isoform 5 [Mus musculus] 237504 2118 5.976666667 4.583333333 -0.38294387 Down 0.447769754 Rassf9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 K09856|1|0.0|867|mmu:237504|Ras association domain-containing protein 9/10 GO:0030658//transport vesicle membrane;GO:0005768//endosome GO:0016491//oxidoreductase activity;GO:0005515//protein binding GO:0044765//single-organism transport;GO:0007154//cell communication;GO:0006886//intracellular protein transport gi|22122815|ref|NP_666352.1|/0/ras association domain-containing protein 9 [Mus musculus] 67826 1837 23.3 27.49666667 0.238926781 Up 0.447506488 Snap47 "synaptosomal-associated protein, 47" K18212|1|0.0|776|mmu:67826|synaptosomal-associated protein 47 GO:0031082 - - gi|21362303|ref|NP_653104.1|/0/synaptosomal-associated protein 47 [Mus musculus] 53817 1756 48.19333333 56.14333333 0.220281132 Up 0.447365452 Ddx39b DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B K12812|1|0.0|849|lve:103084702|ATP-dependent RNA helicase UAP56/SUB2 [EC:3.6.4.13] GO:0030532//small nuclear ribonucleoprotein complex;GO:0016604//nuclear body;GO:0043234//protein complex;GO:0030532//small nuclear ribonucleoprotein complex;GO:0016604//nuclear body;GO:0043234//protein complex "GO:0003724//RNA helicase activity;GO:0032550;GO:0005515//protein binding;GO:0017069//snRNA binding;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity;GO:0032550;GO:0005515//protein binding;GO:0017069//snRNA binding;GO:0042623//ATPase activity, coupled" "GO:0006406//mRNA export from nucleus;GO:0000398//mRNA splicing, via spliceosome;GO:0006406//mRNA export from nucleus;GO:0000398//mRNA splicing, via spliceosome" gi|640818029|ref|XP_008065870.1|/0/PREDICTED: spliceosome RNA helicase DDX39B [Tarsius syrichta] 30045 1305 4.95 6.38 0.366127899 Up 0.447271428 Dnajc12 DnaJ heat shock protein family (Hsp40) member C12 K09532|1|1e-113|412|mmu:30045|DnaJ homolog subfamily C member 12 - - - - 101966 679 126.6566667 146.3933333 0.208926839 Up 0.447262026 D8Ertd738e "DNA segment, Chr 8, ERATO Doi 738, expressed" - - - - gi|56090602|ref|NP_001007572.1|/4.49306e-34/leydig cell tumor 10 kDa protein homolog [Mus musculus] 20333 1815 11.11666667 13.48333333 0.278452941 Up 0.447233818 Sec22b "SEC22 homolog B, vesicle trafficking protein" K08517|1|2e-105|385|tup:102496972|vesicle transport protein SEC22 GO:0012505//endomembrane system;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0048770 GO:0005488//binding GO:0016482//cytosolic transport;GO:0045184//establishment of protein localization gi|537271430|gb|ERE92071.1|/1.85302e-104/vesicle-trafficking protein SEC22b precursor [Cricetulus griseus] 12288 13063.84 27.05333333 22.88666667 -0.241299008 Down 0.447224416 Cacna1c "calcium channel, voltage-dependent, L type, alpha 1C subunit" K04850|1|0.0|3701|mmu:12288|voltage-dependent calcium channel L type alpha-1C GO:0044327//dendritic spine head;GO:0034704//calcium channel complex;GO:0043231//intracellular membrane-bounded organelle;GO:0097060//synaptic membrane;GO:0044297//cell body;GO:0031674//I band;GO:0042383//sarcolemma;GO:0044327//dendritic spine head;GO:0034704//calcium channel complex;GO:0043231//intracellular membrane-bounded organelle;GO:0097060//synaptic membrane;GO:0044297//cell body;GO:0031674//I band;GO:0042383//sarcolemma;GO:0044327//dendritic spine head;GO:0034704//calcium channel complex;GO:0043231//intracellular membrane-bounded organelle;GO:0097060//synaptic membrane;GO:0044297//cell body;GO:0031674//I band;GO:0042383//sarcolemma;GO:0005901//caveola;GO:0044327//dendritic spine head;GO:0034704//calcium channel complex;GO:0043231//intracellular membrane-bounded organelle;GO:0097060//synaptic membrane;GO:0044297//cell body;GO:0031674//I band;GO:0042383//sarcolemma;GO:0044327//dendritic spine head;GO:0034704//calcium channel complex;GO:0043231//intracellular membrane-bounded organelle;GO:0097060//synaptic membrane;GO:0044297//cell body;GO:0031674//I band;GO:0042383//sarcolemma;GO:0044327//dendritic spine head;GO:0034704//calcium channel complex;GO:0043231//intracellular membrane-bounded organelle;GO:0097060//synaptic membrane;GO:0044297//cell body;GO:0031674//I band;GO:0042383//sarcolemma GO:0005245//voltage-gated calcium channel activity;GO:0042805//actinin binding;GO:0043169//cation binding;GO:0019903//protein phosphatase binding;GO:0005245//voltage-gated calcium channel activity;GO:0042805//actinin binding;GO:0043169//cation binding;GO:0019903//protein phosphatase binding;GO:0005245//voltage-gated calcium channel activity;GO:0042805//actinin binding;GO:0043169//cation binding;GO:0019903//protein phosphatase binding;GO:0005245//voltage-gated calcium channel activity;GO:0042805//actinin binding;GO:0043169//cation binding;GO:0019903//protein phosphatase binding;GO:0005245//voltage-gated calcium channel activity;GO:0042805//actinin binding;GO:0043169//cation binding;GO:0019903//protein phosphatase binding;GO:0005245//voltage-gated calcium channel activity;GO:0042805//actinin binding;GO:0043169//cation binding;GO:0019903//protein phosphatase binding GO:0033500//carbohydrate homeostasis;GO:0035265//organ growth;GO:0007632//visual behavior;GO:0006887//exocytosis;GO:0042310//vasoconstriction;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0030072//peptide hormone secretion;GO:0070588//calcium ion transmembrane transport;GO:0014832//urinary bladder smooth muscle contraction;GO:0008344//adult locomotory behavior;GO:0033500//carbohydrate homeostasis;GO:0035265//organ growth;GO:0007632//visual behavior;GO:0006887//exocytosis;GO:0042310//vasoconstriction;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0030072//peptide hormone secretion;GO:0070588//calcium ion transmembrane transport;GO:0014832//urinary bladder smooth muscle contraction;GO:0008344//adult locomotory behavior;GO:0033500//carbohydrate homeostasis;GO:0035265//organ growth;GO:0007632//visual behavior;GO:0006887//exocytosis;GO:0042310//vasoconstriction;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0030072//peptide hormone secretion;GO:0070588//calcium ion transmembrane transport;GO:0014832//urinary bladder smooth muscle contraction;GO:0008344//adult locomotory behavior;GO:0033500//carbohydrate homeostasis;GO:0035265//organ growth;GO:0007632//visual behavior;GO:0006887//exocytosis;GO:0042310//vasoconstriction;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0030072//peptide hormone secretion;GO:0070588//calcium ion transmembrane transport;GO:0014832//urinary bladder smooth muscle contraction;GO:0008344//adult locomotory behavior;GO:0033500//carbohydrate homeostasis;GO:0035265//organ growth;GO:0007632//visual behavior;GO:0006887//exocytosis;GO:0042310//vasoconstriction;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0030072//peptide hormone secretion;GO:0070588//calcium ion transmembrane transport;GO:0014832//urinary bladder smooth muscle contraction;GO:0008344//adult locomotory behavior;GO:0033500//carbohydrate homeostasis;GO:0035265//organ growth;GO:0007632//visual behavior;GO:0006887//exocytosis;GO:0042310//vasoconstriction;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0030072//peptide hormone secretion;GO:0070588//calcium ion transmembrane transport;GO:0014832//urinary bladder smooth muscle contraction;GO:0008344//adult locomotory behavior gi|364502983|ref|NP_001242926.1|/0/voltage-dependent L-type calcium channel subunit alpha-1C isoform 5 [Mus musculus] 232087 2804 48.31333333 56.19666667 0.218063165 Up 0.447186807 Mat2a "methionine adenosyltransferase II, alpha" K00789|1|0.0|764|ngi:103739791|S-adenosylmethionine synthetase [EC:2.5.1.6] GO:0044444//cytoplasmic part "GO:0043169//cation binding;GO:0032550;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups" GO:0044710;GO:0046683//response to organophosphorus;GO:0009108//coenzyme biosynthetic process;GO:0009719;GO:0006790//sulfur compound metabolic process;GO:0048511//rhythmic process;GO:0006807//nitrogen compound metabolic process "gi|148666566|gb|EDK98982.1|/0/mCG129313, isoform CRA_a [Mus musculus]" 654812 2062 6.17 7.783333333 0.335117655 Up 0.44712099 Angptl7 angiopoietin-like 7 K05466|1|2e-53|213|mze:101467910|angiopoietin 2;K10104|3|2e-52|209|bfo:BRAFLDRAFT_252163|ficolin;K05467|4|3e-52|209|mcf:102121734|angiopoietin 4 - - - gi|564306469|ref|XP_006225684.1|/0/PREDICTED: angiopoietin-related protein 7 [Rattus norvegicus] 239319 4531 3.336666667 2.323333333 -0.522211413 Down 0.44708338 Card6 "caspase recruitment domain family, member 6" K12797|1|0.0|2135|mmu:239319|caspase recruitment domain-containing protein 6 - - - gi|253314487|ref|NP_001156610.1|/0/caspase recruitment domain-containing protein 6 [Mus musculus] 105675 1560 145.1533333 125.8333333 -0.206063559 Down 0.44708338 Ppif peptidylprolyl isomerase F (cyclophilin F) K09565|1|4e-84|314|mmu:105675|peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8] GO:0005743//mitochondrial inner membrane GO:0008144//drug binding;GO:0033218//amide binding;GO:0016859//cis-trans isomerase activity GO:0010155//regulation of proton transport;GO:0043462//regulation of ATPase activity;GO:0032410//negative regulation of transporter activity;GO:0018208//peptidyl-proline modification;GO:0034614//cellular response to reactive oxygen species;GO:0010823//negative regulation of mitochondrion organization;GO:0070265//necrotic cell death;GO:0051592//response to calcium ion;GO:0046685//response to arsenic-containing substance;GO:0010822//positive regulation of mitochondrion organization;GO:0097193//intrinsic apoptotic signaling pathway;GO:0002082//regulation of oxidative phosphorylation;GO:0006839//mitochondrial transport "gi|19527310|ref|NP_598845.1|/3.28594e-83/peptidyl-prolyl cis-trans isomerase F, mitochondrial precursor [Mus musculus]" 19301 1035 55.65 47.83333333 -0.218365357 Down 0.447017564 Pxmp2 peroxisomal membrane protein 2 K13347|1|5e-83|310|mmu:19301|peroxisomal membrane protein 2 GO:0031231//intrinsic component of peroxisomal membrane;GO:0032991//macromolecular complex GO:0005488//binding - gi|112421058|ref|NP_033019.2|/4.4546e-82/peroxisomal membrane protein 2 [Mus musculus] 59046 3969.28 13.20333333 10.84 -0.284537444 Down 0.446979954 Arpp19 cAMP-regulated phosphoprotein 19 - GO:0044424;GO:0044424 GO:0019888//protein phosphatase regulator activity;GO:0019903//protein phosphatase binding;GO:0016247//channel regulator activity;GO:0019212//phosphatase inhibitor activity;GO:0019888//protein phosphatase regulator activity;GO:0019903//protein phosphatase binding;GO:0016247//channel regulator activity;GO:0019212//phosphatase inhibitor activity GO:0007265//Ras protein signal transduction;GO:0044092//negative regulation of molecular function;GO:0044772//mitotic cell cycle phase transition;GO:0000087//mitotic M phase;GO:0006094//gluconeogenesis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007265//Ras protein signal transduction;GO:0044092//negative regulation of molecular function;GO:0044772//mitotic cell cycle phase transition;GO:0000087//mitotic M phase;GO:0006094//gluconeogenesis;GO:0007186//G-protein coupled receptor signaling pathway gi|217416411|ref|NP_001136127.1|/2.85681e-53/cAMP-regulated phosphoprotein 19 isoform 2 [Mus musculus] 19384 2288 45.49666667 53.17333333 0.22494206 Up 0.446679078 Ran "RAN, member RAS oncogene family" K07936|1|3e-119|432|nle:100599771|GTP-binding nuclear protein Ran GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0005635//nuclear envelope;GO:0048770;GO:0044427 GO:0035258//steroid hormone receptor binding;GO:0003712//transcription cofactor activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 "GO:0007010//cytoskeleton organization;GO:0006351//transcription, DNA-templated;GO:0000087//mitotic M phase;GO:0031503//protein complex localization;GO:0009154//purine ribonucleotide catabolic process;GO:0051169//nuclear transport;GO:0006886//intracellular protein transport;GO:0043393//regulation of protein binding;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0007281//germ cell development;GO:0050658//RNA transport;GO:0035556//intracellular signal transduction" gi|585714846|ref|XP_006901057.1|/3.55505e-119/PREDICTED: GTP-binding nuclear protein Ran [Elephantulus edwardii] 69186 431 114.9666667 133.0366667 0.210608298 Up 0.446556847 Tmem256 transmembrane protein 256 - GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane - - gi|672067804|ref|XP_008766025.1|/8.0349e-46/PREDICTED: transmembrane protein 256 isoform X1 [Rattus norvegicus] 233733 2595 8.673333333 10.67666667 0.299802836 Up 0.446444018 Galnt18 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18 K00710|1|0.0|1207|mmu:233733|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008376//acetylgalactosaminyltransferase activity GO:0006464//cellular protein modification process gi|31982036|ref|NP_776100.2|/0/polypeptide N-acetylgalactosaminyltransferase 18 [Mus musculus] 11305 8061 21.39333333 17.98 -0.250768268 Down 0.446171349 Abca2 "ATP-binding cassette, sub-family A (ABC1), member 2" "K05642|1|0.0|4579|mmu:11305|ATP-binding cassette, subfamily A (ABC1), member 2" GO:0015630//microtubule cytoskeleton;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0016125//sterol metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0009154//purine ribonucleotide catabolic process;GO:0032367//intracellular cholesterol transport;GO:0009725//response to hormone;GO:0055092//sterol homeostasis gi|110225379|ref|NP_031405.2|/0/ATP-binding cassette sub-family A member 2 [Mus musculus] 229542 1912 4.433333333 3.276666667 -0.436162924 Down 0.44609613 Gatad2b GATA zinc finger domain containing 2B K10310|1|1e-19|100|nvi:100122742|F-box protein 33 - - - - 74840 2206 12.60333333 15.16666667 0.267098696 Up 0.446011509 Manf mesencephalic astrocyte-derived neurotrophic factor K13190|1|2e-94|349|fca:101090926|RNA-binding protein 15 GO:0044421;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005102//receptor binding GO:0035966//response to topologically incorrect protein;GO:0001980//regulation of systemic arterial blood pressure by ischemic conditions gi|110625813|ref|NP_083379.2|/3.30674e-98/mesencephalic astrocyte-derived neurotrophic factor precursor [Mus musculus] 68927 1675 35.45 30.25 -0.228850485 Down 0.445767047 Ptcd2 pentatricopeptide repeat domain 2 K17711|1|0.0|705|mmu:68927|pentatricopeptide repeat domain-containing protein 2 GO:0043231//intracellular membrane-bounded organelle - GO:0006996//organelle organization;GO:0003208//cardiac ventricle morphogenesis;GO:0006397//mRNA processing;GO:0055002//striated muscle cell development "gi|58037131|ref|NP_081149.1|/0/pentatricopeptide repeat-containing protein 2, mitochondrial [Mus musculus]" 50883 2247 6.046666667 7.636666667 0.336803003 Up 0.445729437 Chek2 checkpoint kinase 2 K06641|1|0.0|943|mmu:50883|serine/threonine-protein kinase Chk2 [EC:2.7.11.1] GO:0044427;GO:0016604//nuclear body GO:0032550;GO:0044389//ubiquitin-like protein ligase binding;GO:0004672//protein kinase activity;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0019900//kinase binding "GO:0006351//transcription, DNA-templated;GO:0044772//mitotic cell cycle phase transition;GO:0012501//programmed cell death;GO:0007052//mitotic spindle organization;GO:0009894;GO:0006468//protein phosphorylation;GO:0030163//protein catabolic process;GO:0010212//response to ionizing radiation;GO:0000087//mitotic M phase;GO:0031573//intra-S DNA damage checkpoint;GO:0035556//intracellular signal transduction;GO:0006281//DNA repair" gi|7710088|ref|NP_057890.1|/0/serine/threonine-protein kinase Chk2 [Mus musculus] 13078 5128 2.133333333 3.103333333 0.540709263 Up 0.44570123 Cyp1b1 "cytochrome P450, family 1, subfamily b, polypeptide 1" "K07410|1|0.0|959|mmu:13078|cytochrome P450, family 1, subfamily B, polypeptide 1 [EC:1.14.14.1]" GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0016477//cell migration;GO:0090136//epithelial cell-cell adhesion;GO:0019748//secondary metabolic process;GO:0042221//response to chemical;GO:0001944//vasculature development;GO:0006725//cellular aromatic compound metabolic process;GO:0008202//steroid metabolic process gi|6753568|ref|NP_034124.1|/0/cytochrome P450 1B1 [Mus musculus] 74478 2677 1.386666667 0.703333333 -0.979340529 Down 0.445682425 Snx29 sorting nexin 29 K17935|1|0.0|837|mmu:74478|sorting nexin-29 - GO:0005543//phospholipid binding GO:0044763 gi|588480422|ref|NP_001277077.1|/0/sorting nexin-29 isoform b [Mus musculus] 20661 6851 6.52 8.19 0.328991487 Up 0.445550792 Sort1 sortilin 1 K12388|1|0.0|1501|mmu:20661|sortilin GO:0043005//neuron projection;GO:0030135//coated vesicle;GO:0044297//cell body;GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0012505//endomembrane system;GO:0005798//Golgi-associated vesicle;GO:0043005//neuron projection;GO:0030135//coated vesicle;GO:0044297//cell body;GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0012505//endomembrane system;GO:0005798//Golgi-associated vesicle GO:0043121//neurotrophin binding;GO:0005030//neurotrophin receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0043121//neurotrophin binding;GO:0005030//neurotrophin receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0051004;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010467//gene expression;GO:0006915//apoptotic process;GO:0016197//endosomal transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007041//lysosomal transport;GO:0006996//organelle organization;GO:0043434//response to peptide hormone;GO:0035914//skeletal muscle cell differentiation;GO:0015758//glucose transport;GO:0006892//post-Golgi vesicle-mediated transport;GO:0051004;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010467//gene expression;GO:0006915//apoptotic process;GO:0016197//endosomal transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007041//lysosomal transport;GO:0006996//organelle organization;GO:0043434//response to peptide hormone;GO:0035914//skeletal muscle cell differentiation;GO:0015758//glucose transport;GO:0006892//post-Golgi vesicle-mediated transport gi|568922256|ref|XP_006501286.1|/0/PREDICTED: sortilin isoform X1 [Mus musculus] 56526 3709.8 2.326666667 3.326666667 0.515812779 Up 0.445550792 6-Sep septin 6 K16939|1|0.0|721|mmu:56526|septin 6/8/11 "GO:0030136//clathrin-coated vesicle;GO:0033267;GO:0000775//chromosome, centromeric region;GO:0032156//septin cytoskeleton;GO:0030136//clathrin-coated vesicle;GO:0033267;GO:0000775//chromosome, centromeric region;GO:0032156//septin cytoskeleton;GO:0030136//clathrin-coated vesicle;GO:0033267;GO:0000775//chromosome, centromeric region;GO:0032156//septin cytoskeleton;GO:0030136//clathrin-coated vesicle;GO:0033267;GO:0000775//chromosome, centromeric region;GO:0032156//septin cytoskeleton" GO:0032550;GO:0032550;GO:0032550;GO:0032550 GO:0044763;GO:0044763;GO:0044763;GO:0044763 gi|768039038|ref|XP_011529619.1|/0/PREDICTED: septin-6 isoform X2 [Homo sapiens] 66044 1283 10.65666667 12.97333333 0.283792966 Up 0.445494377 Dtd1 D-tyrosyl-tRNA deacylase 1 K07560|1|4e-114|414|mmu:66044|D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-] GO:0031981//nuclear lumen GO:0016787//hydrolase activity GO:0046416//D-amino acid metabolic process gi|13384676|ref|NP_079590.1|/3.03326e-113/D-tyrosyl-tRNA(Tyr) deacylase 1 [Mus musculus] 67398 2934 45.23 52.56333333 0.216776772 Up 0.445484975 Srpr signal recognition particle receptor ('docking protein') K13431|1|0.0|1095|mmu:67398|signal recognition particle receptor subunit alpha GO:0031224//intrinsic component of membrane;GO:0030867//rough endoplasmic reticulum membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0043021//ribonucleoprotein complex binding GO:0010467//gene expression;GO:0009154//purine ribonucleotide catabolic process;GO:0006613//cotranslational protein targeting to membrane;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0019538//protein metabolic process gi|27229036|ref|NP_080406.1|/0/signal recognition particle receptor subunit alpha [Mus musculus] 19079 2051 22.70666667 26.73 0.235343903 Up 0.445475573 Prkab1 "protein kinase, AMP-activated, beta 1 non-catalytic subunit" "K07199|1|8e-149|530|mmu:19079|5'-AMP-activated protein kinase, regulatory beta subunit" GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0004674//protein serine/threonine kinase activity;GO:0019900//kinase binding GO:0050896//response to stimulus;GO:0006631//fatty acid metabolic process;GO:0051259//protein oligomerization;GO:0019222//regulation of metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0010467//gene expression gi|23956234|ref|NP_114075.1|/7.10456e-148/5'-AMP-activated protein kinase subunit beta-1 [Mus musculus] 71183 1523 0.07 0.503333333 2.846087317 Up 0.445362744 Clec12b "C-type lectin domain family 12, member B" K17517|1|2e-138|495|mmu:71183|C-type lectin domain family 12 member B GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding - gi|568942881|ref|XP_006506674.1|/3.47826e-138/PREDICTED: C-type lectin domain family 12 member B isoform X2 [Mus musculus] 665211 1099.79 3.13 4.263333333 0.445819201 Up 0.445334537 Gm14326 predicted gene 14326 K09228|1|5e-31|137|mmu:665211|KRAB domain-containing zinc finger protein - - - "gi|298231518|ref|NP_001177231.1|/0/novel KRAB box and zinc finger, C2H2 type domain containing protein isoform 1 [Mus musculus] " 320878 4662.03 34.79666667 29.63666667 -0.231565918 Down 0.445325134 Mical2 "microtubule associated monooxygenase, calponin and LIM domain containing 2" K19947|1|0.0|1854|ngi:103750410|protein-methionine sulfoxide oxidase MICAL [EC:1.14.13.-] GO:0043232;GO:0043232 GO:0050660//flavin adenine dinucleotide binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0004497//monooxygenase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0004497//monooxygenase activity GO:0044710;GO:0008154//actin polymerization or depolymerization;GO:0044710;GO:0008154//actin polymerization or depolymerization gi|60360344|dbj|BAD90416.1|/0/mKIAA0750 protein [Mus musculus] 22378 1795 99.56333333 115.06 0.208699938 Up 0.44507127 Wbp2 WW domain binding protein 2 - - - - gi|829835808|ref|XP_012634295.1|/2.56352e-90/PREDICTED: WW domain-binding protein 2 isoform X1 [Microcebus murinus] 105278 1854 1.223333333 2.02 0.723537731 Up 0.445024258 Cdk20 cyclin-dependent kinase 20 K08817|1|0.0|667|mmu:105278|cell cycle related kinase [EC:2.7.11.22];K10267|5|0.0|654|aml:100468585|F-box and WD-40 domain protein 12/13/14/15/16/17/19 GO:0043231//intracellular membrane-bounded organelle GO:0004674//protein serine/threonine kinase activity;GO:0032550 GO:0044763;GO:0032502//developmental process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|16716469|ref|NP_444410.1|/0/cyclin-dependent kinase 20 [Mus musculus] 19763 2048 8.553333333 10.52666667 0.299490001 Up 0.445014856 Ring1 ring finger protein 1 K10695|1|1e-143|513|mmu:19763|E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27] GO:0043232;GO:0044451;GO:0031519//PcG protein complex GO:0005488//binding "GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0016574//histone ubiquitination" gi|884926991|ref|XP_013012447.1|/5.25898e-143/PREDICTED: E3 ubiquitin-protein ligase RING1 isoform X1 [Cavia porcellus] 236733 3464 2.48 3.506666667 0.499760178 Up 0.445014856 Usp11 ubiquitin specific peptidase 11 K11835|1|0.0|1756|mmu:236733|ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle GO:0019783//ubiquitin-like protein-specific protease activity;GO:0004175//endopeptidase activity;GO:0005488//binding;GO:0016790//thiolester hydrolase activity GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process gi|164663834|ref|NP_663603.3|/0/ubiquitin carboxyl-terminal hydrolase 11 [Mus musculus] 23871 5018.01 17.33333333 14.50666667 -0.256833067 Down 0.444939637 Ets1 "E26 avian leukemia oncogene 1, 5' domain" K02678|1|0.0|883|mmu:23871|C-ets GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0001525//angiogenesis;GO:0044703;GO:0021536//diencephalon development;GO:0009605//response to external stimulus;GO:0022617//extracellular matrix disassembly;GO:0006366//transcription from RNA polymerase II promoter;GO:0034614//cellular response to reactive oxygen species;GO:0008283//cell proliferation;GO:0009636//response to toxic substance;GO:0043627//response to estrogen;GO:0022602//ovulation cycle process;GO:0034405//response to fluid shear stress;GO:0034097//response to cytokine;GO:0051726//regulation of cell cycle;GO:0012502//induction of programmed cell death;GO:0030218//erythrocyte differentiation;GO:0030575//nuclear body organization;GO:0016477//cell migration;GO:0001525//angiogenesis;GO:0044703;GO:0021536//diencephalon development;GO:0009605//response to external stimulus;GO:0022617//extracellular matrix disassembly;GO:0006366//transcription from RNA polymerase II promoter;GO:0034614//cellular response to reactive oxygen species;GO:0008283//cell proliferation;GO:0009636//response to toxic substance;GO:0043627//response to estrogen;GO:0022602//ovulation cycle process;GO:0034405//response to fluid shear stress;GO:0034097//response to cytokine;GO:0051726//regulation of cell cycle;GO:0012502//induction of programmed cell death;GO:0030218//erythrocyte differentiation;GO:0030575//nuclear body organization;GO:0016477//cell migration gi|84579950|ref|NP_001033731.1|/0/protein C-ets-1 isoform 2 [Mus musculus] 77106 4430 5.086666667 3.833333333 -0.408121101 Down 0.444939637 Tmem181a transmembrane protein 181A - - GO:0005488//binding - gi|75677514|ref|NP_001028350.1|/0/transmembrane protein 181 [Mus musculus] 18205 1358.79 3.2 2.223333333 -0.525347644 Down 0.444892625 Ntf3 neurotrophin 3 K04356|1|2e-149|523|ngi:103727536|neurotrophin 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005165//neurotrophin receptor binding;GO:0043121//neurotrophin binding;GO:0005165//neurotrophin receptor binding;GO:0043121//neurotrophin binding;GO:0005165//neurotrophin receptor binding;GO:0043121//neurotrophin binding GO:0009888//tissue development;GO:0042692//muscle cell differentiation;GO:0001709//cell fate determination;GO:0007268//chemical synaptic transmission;GO:0031532//actin cytoskeleton reorganization;GO:0032147//activation of protein kinase activity;GO:0001933//negative regulation of protein phosphorylation;GO:0016477//cell migration;GO:0010001//glial cell differentiation;GO:0008366//axon ensheathment;GO:0030182//neuron differentiation;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0048483//autonomic nervous system development;GO:0002090//regulation of receptor internalization;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0050927//positive regulation of positive chemotaxis;GO:0009888//tissue development;GO:0042692//muscle cell differentiation;GO:0001709//cell fate determination;GO:0007268//chemical synaptic transmission;GO:0031532//actin cytoskeleton reorganization;GO:0032147//activation of protein kinase activity;GO:0001933//negative regulation of protein phosphorylation;GO:0016477//cell migration;GO:0010001//glial cell differentiation;GO:0008366//axon ensheathment;GO:0030182//neuron differentiation;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0048483//autonomic nervous system development;GO:0002090//regulation of receptor internalization;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0050927//positive regulation of positive chemotaxis;GO:0009888//tissue development;GO:0042692//muscle cell differentiation;GO:0001709//cell fate determination;GO:0007268//chemical synaptic transmission;GO:0031532//actin cytoskeleton reorganization;GO:0032147//activation of protein kinase activity;GO:0001933//negative regulation of protein phosphorylation;GO:0016477//cell migration;GO:0010001//glial cell differentiation;GO:0008366//axon ensheathment;GO:0030182//neuron differentiation;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0048483//autonomic nervous system development;GO:0002090//regulation of receptor internalization;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0050927//positive regulation of positive chemotaxis "gi|149049385|gb|EDM01839.1|/6.40853e-173/neurotrophin 3, isoform CRA_a [Rattus norvegicus]" 28084 1114.49 94.65333333 109.6566667 0.212268306 Up 0.444629358 Vps25 vacuolar protein sorting 25 K12189|1|6e-100|366|cge:100760885|ESCRT-II complex subunit VPS25 GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane - "GO:0045184//establishment of protein localization;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045184//establishment of protein localization;GO:0045184//establishment of protein localization;GO:0006351//transcription, DNA-templated;GO:0045184//establishment of protein localization;GO:0006351//transcription, DNA-templated" gi|548923845|ref|NP_001271341.1|/4.56804e-98/vacuolar protein-sorting-associated protein 25 isoform 3 [Mus musculus] 12051 1835 4.526666667 5.88 0.377367081 Up 0.444413103 Bcl3 B cell leukemia/lymphoma 3 K09258|1|0.0|786|mmu:12051|B-cell CLL/lymphoma protein 3 GO:0043231//intracellular membrane-bounded organelle;GO:0033256//I-kappaB/NF-kappaB complex;GO:0044444//cytoplasmic part GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003676//nucleic acid binding GO:0042348//NF-kappaB import into nucleus;GO:0042770//signal transduction in response to DNA damage;GO:0043062//extracellular structure organization;GO:0001562//response to protozoan;GO:0006952//defense response;GO:0009411//response to UV;GO:0042036//negative regulation of cytokine biosynthetic process;GO:0002266;GO:0001819//positive regulation of cytokine production;GO:0002313//mature B cell differentiation involved in immune response;GO:0042091;GO:0051098//regulation of binding;GO:0006366//transcription from RNA polymerase II promoter;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006412//translation;GO:0042092//type 2 immune response;GO:0006959//humoral immune response;GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains gi|164607184|ref|NP_291079.2|/0/B-cell lymphoma 3 protein homolog [Mus musculus] 20222 1674 42.32 49.31333333 0.220638148 Up 0.444300275 Sf3a2 "splicing factor 3a, subunit 2" K12826|1|3e-92|341|pale:102884451|splicing factor 3A subunit 2 - - - - 17919 6647 6.893333333 5.393333333 -0.354024578 Down 0.444027605 Myo5b myosin VB K10357|1|0.0|3460|mmu:17919|myosin V GO:0032991//macromolecular complex;GO:0030425//dendrite;GO:0044297//cell body;GO:0015629//actin cytoskeleton;GO:0044444//cytoplasmic part GO:0008092//cytoskeletal protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017016//Ras GTPase binding;GO:0035254//glutamate receptor binding GO:0006810//transport;GO:0045184//establishment of protein localization gi|46399202|ref|NP_963894.1|/0/unconventional myosin-Vb [Mus musculus] 72136 2089 4.2 5.503333333 0.389916387 Up 0.443971191 Chst14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 K08105|1|0.0|723|mmu:72136|dermatan 4-sulfotransferase 1 [EC:2.8.2.35] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0005488//binding;GO:0016782//transferase activity, transferring sulfur-containing groups" GO:0006029//proteoglycan metabolic process;GO:0044723;GO:0006024//glycosaminoglycan biosynthetic process gi|254540084|ref|NP_082393.3|/0/carbohydrate sulfotransferase 14 [Mus musculus] 81845 1395.3 9.46 11.55 0.287980763 Up 0.443924179 Gpank1 G patch domain and ankyrin repeats 1 - - GO:0005488//binding;GO:0005488//binding - gi|190610032|ref|NP_115849.2|/0/G patch domain and ankyrin repeat-containing protein 1 isoform 1 precursor [Mus musculus] 72124 2637.89 9.556666667 11.65 0.285750551 Up 0.443924179 Seh1l SEH1-like (S. cerevisiae K14299|1|0.0|685|mmu:72124|nucleoporin SEH1 GO:0005643//nuclear pore;GO:0000776//kinetochore;GO:0044444//cytoplasmic part;GO:0005643//nuclear pore;GO:0000776//kinetochore;GO:0044444//cytoplasmic part - GO:0044238//primary metabolic process;GO:0000070//mitotic sister chromatid segregation;GO:0044710;GO:0044764;GO:0050658//RNA transport;GO:0045184//establishment of protein localization;GO:0015758//glucose transport;GO:0007166//cell surface receptor signaling pathway;GO:0006997//nucleus organization;GO:0044238//primary metabolic process;GO:0000070//mitotic sister chromatid segregation;GO:0044710;GO:0044764;GO:0050658//RNA transport;GO:0045184//establishment of protein localization;GO:0015758//glucose transport;GO:0007166//cell surface receptor signaling pathway;GO:0006997//nucleus organization gi|84875515|ref|NP_001034177.1|/0/nucleoporin SEH1 isoform a [Mus musculus] 93760 8175 14.61333333 12.12 -0.269895599 Down 0.443905374 Arid1a AT rich interactive domain 1A (SWI-like) K11653|1|0.0|2794|mmu:93760|AT-rich interactive domain-containing protein 1 GO:0090544//BAF-type complex GO:0005102//receptor binding "GO:0016568//chromatin modification;GO:0006351//transcription, DNA-templated;GO:0034728//nucleosome organization;GO:0031958" gi|124249109|ref|NP_001074288.1|/0/AT-rich interactive domain-containing protein 1A [Mus musculus] 100503178 2033 3.21 4.353333333 0.439547194 Up 0.443867765 2810013P06Rik RIKEN cDNA 2810013P06 gene - - - - - 246256 1250 1.193333333 1.98 0.730503344 Up 0.443717327 Fcgr4 "Fc receptor, IgG, low affinity IV" K06463|1|1e-146|521|mmu:246256|low affinity immunoglobulin gamma Fc region receptor III GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0019865//immunoglobulin binding GO:0009611//response to wounding;GO:0002376//immune system process;GO:0019233//sensory perception of pain;GO:0032496//response to lipopolysaccharide gi|224922770|ref|NP_653142.2|/9.92601e-146/low affinity immunoglobulin gamma Fc region receptor III-A precursor [Mus musculus] 70248 2093.69 40.63 47.44666667 0.223761371 Up 0.443642108 Dazap1 DAZ associated protein 1 K14411|1|1e-159|565|rno:362836|RNA-binding protein Musashi GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen;GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen;GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding GO:0001890//placenta development;GO:0048232//male gamete generation;GO:0001890//placenta development;GO:0048232//male gamete generation;GO:0001890//placenta development;GO:0048232//male gamete generation gi|71043670|ref|NP_001020913.1|/1.19898e-158/DAZ-associated protein 1 [Rattus norvegicus] 233103 5808 10.39333333 8.45 -0.298635181 Down 0.443510474 4931406P16Rik RIKEN cDNA 4931406P16 gene - - - - gi|27370084|ref|NP_766329.1|/0/uncharacterized protein KIAA0355 homolog [Mus musculus] 69812 519 1.42 0.74 -0.940293754 Down 0.443237805 Abhd11os "abhydrolase domain containing 11, opposite strand" K16756|1|1e-06|54.3|cmk:103180674|coiled-coil domain-containing protein 64 - - - - 13401 2520 40.03 46.73 0.223267421 Up 0.443143781 Dmwd dystrophia myotonica-containing WD repeat motif K06100|1|1e-124|450|aam:106490508|symplekin;K14855|5|2e-10|70.5|tca:661129|ribosome assembly protein 4 - - GO:0022403 gi|225637538|ref|NP_034188.2|/0/dystrophia myotonica WD repeat-containing protein [Mus musculus] 224132 4554 13.96 16.70666667 0.259124972 Up 0.443087367 Dirc2 disrupted in renal carcinoma 2 (human) "K15381|1|0.0|796|mmu:224132|MFS transporter, FLVCR family, disrupted in renal carcinoma protein 2" GO:0005764//lysosome;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763 gi|148665474|gb|EDK97890.1|/0/disrupted in renal carcinoma 2 (human) [Mus musculus] 56791 1402 9.276666667 11.35 0.29101389 Up 0.443030953 Ube2l6 ubiquitin-conjugating enzyme E2L 6 K04553|1|8e-84|313|mmu:56791|ubiquitin-conjugating enzyme E2 L6 [EC:2.3.2.23] - - - - 68240 655 4.7 6.083333333 0.372201301 Up 0.442965136 Rpa3 replication protein A3 K10740|1|7e-64|245|mmu:68240|replication factor A3 GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0043566//structure-specific DNA binding GO:0006289//nucleotide-excision repair;GO:0045003//double-strand break repair via synthesis-dependent strand annealing;GO:0000723//telomere maintenance;GO:0044772//mitotic cell cycle phase transition;GO:0006261//DNA-dependent DNA replication;GO:0051320 gi|13386122|ref|NP_080908.1|/5.55794e-63/replication protein A 14 kDa subunit [Mus musculus] 74322 2537 20.73666667 24.54333333 0.243147195 Up 0.442871112 Cxxc1 CXXC finger 1 (PHD domain) K14960|1|0.0|1123|mmu:74322|COMPASS component SPP1 GO:0035097//histone methyltransferase complex;GO:0016604//nuclear body;GO:0034399//nuclear periphery GO:0046914//transition metal ion binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0043565//sequence-specific DNA binding "GO:0034968//histone lysine methylation;GO:0006351//transcription, DNA-templated" gi|18390325|ref|NP_083144.1|/0/CXXC-type zinc finger protein 1 [Mus musculus] 71323 1733 4.966666667 3.733333333 -0.411813598 Down 0.442777088 Rassf8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 K09855|1|0.0|686|mmu:71323|Ras association domain-containing protein 7/8 - - GO:0007154//cell communication gi|23503231|ref|NP_082036.1|/0/ras association domain-containing protein 8 [Mus musculus] 72655 1084 1.656666667 2.53 0.610854034 Up 0.442617248 Snhg5 small nucleolar RNA host gene 5 - - - - gi|21432062|gb|AAH32970.1|/1.16525e-11/2810026P18Rik protein [Mus musculus] 23837 1215 21.18666667 24.97666667 0.237424327 Up 0.442579638 Cfdp1 craniofacial development protein 1 K14537|1|8e-26|120|pxy:105393988|nuclear GTP-binding protein - - GO:0022604//regulation of cell morphogenesis;GO:0008283//cell proliferation;GO:0022610;GO:0006915//apoptotic process gi|6753412|ref|NP_035931.1|/3.90385e-123/craniofacial development protein 1 [Mus musculus] 228859 1643 89.96333333 77.62666667 -0.212784778 Down 0.442551431 Fitm2 fat storage-inducing transmembrane protein 2 - GO:0031227//intrinsic component of endoplasmic reticulum membrane - GO:0006996//organelle organization;GO:0055082//cellular chemical homeostasis;GO:0000902//cell morphogenesis;GO:0019432//triglyceride biosynthetic process;GO:0010884//positive regulation of lipid storage "gi|148674382|gb|EDL06329.1|/2.41305e-132/RIKEN cDNA D930001I22, isoform CRA_a, partial [Mus musculus]" 100306952 157 0.01 0.343333333 5.101538026 Up 0.442485614 Snora78 "small nucleolar RNA, H/ACA box 7" - - - - - 67693 620 76.94666667 89.16 0.212537786 Up 0.442448005 Hypk huntingtin interacting protein K - - - - - 78779 2380 5.74 7.283333333 0.343548137 Up 0.44226936 Spata2l spermatogenesis associated 2-like K17595|1|0.0|745|mmu:78779|spermatogenesis-associated protein 2 - - - gi|60360538|dbj|BAD90513.1|/0/mKIAA4138 protein [Mus musculus] 100502834 432 1.583333333 0.87 -0.863877707 Down 0.442259957 Gm15972 predicted gene 15972 - - - - gi|148664566|gb|EDK96982.1|/1.45826e-41/mCG145695 [Mus musculus] 68479 1648 11.60333333 14.03666667 0.274661061 Up 0.442203543 Phf5a PHD finger protein 5A K12834|1|2e-63|246|asn:102377118|PHD finger-like domain-containing protein 5A GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0034399//nuclear periphery GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0000377;GO:0006351//transcription, DNA-templated" gi|961745338|ref|XP_014933353.1|/4.82692e-71/PREDICTED: PHD finger-like domain-containing protein 5A [Acinonyx jubatus] 606496 2276 78.89 90.94333333 0.205125446 Up 0.442203543 Gsk3a glycogen synthase kinase 3 alpha K08822|1|0.0|786|mmu:606496|glycogen synthase kinase 3 alpha [EC:2.7.11.26] GO:0044444//cytoplasmic part GO:0004672//protein kinase activity;GO:0051018//protein kinase A binding;GO:0032550 GO:0051347//positive regulation of transferase activity;GO:0010829//negative regulation of glucose transport;GO:0044026//DNA hypermethylation;GO:0048870//cell motility;GO:0008016//regulation of heart contraction;GO:0014070//response to organic cyclic compound;GO:0008217//regulation of blood pressure;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0001934//positive regulation of protein phosphorylation;GO:0010226//response to lithium ion;GO:0006073//cellular glucan metabolic process;GO:0009968//negative regulation of signal transduction;GO:0006366//transcription from RNA polymerase II promoter;GO:0043086//negative regulation of catalytic activity;GO:0006171//cAMP biosynthetic process;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0003208//cardiac ventricle morphogenesis;GO:0008286//insulin receptor signaling pathway gi|72384361|ref|NP_001026837.1|/0/glycogen synthase kinase-3 alpha [Mus musculus] 28030 2598 90.78333333 78.75 -0.205147538 Down 0.442184738 Gfm1 "G elongation factor, mitochondrial 1" K02355|1|0.0|1457|mmu:28030|elongation factor G GO:0043231//intracellular membrane-bounded organelle "GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008135//translation factor activity, RNA binding" GO:0009154//purine ribonucleotide catabolic process;GO:0006414//translational elongation "gi|170650599|ref|NP_613057.2|/0/elongation factor G, mitochondrial [Mus musculus]" 225339 4781 6.056666667 4.683333333 -0.370988289 Down 0.442137726 Ammecr1l AMME chromosomal region gene 1-like - - - - gi|334848200|ref|NP_001229359.1|/0/AMMECR1-like protein isoform 1 [Mus musculus] 108098 780 20.75333333 24.51 0.240027408 Up 0.442118921 Med21 mediator complex subunit 21 K15152|1|2e-74|280|mmu:108098|mediator of RNA polymerase II transcription subunit 21 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005488//binding;GO:0003712//transcription cofactor activity;GO:0034062//RNA polymerase activity GO:0001701//in utero embryonic development;GO:0006366//transcription from RNA polymerase II promoter "gi|148678764|gb|EDL10711.1|/3.0521e-78/SRB7 (suppressor of RNA polymerase B) homolog (S. cerevisiae), isoform CRA_b, partial [Mus musculus]" 81877 9569 24.32333333 20.56333333 -0.242266807 Down 0.442118921 Tnxb tenascin XB K06252|1|0.0|5715|mmu:81877|tenascin - - - gi|320461717|ref|NP_112453.2|/0/tenascin-X precursor [Mus musculus] 76743 1477 1.933333333 1.16 -0.736965594 Down 0.442081312 Gje1 "gap junction protein, epsilon 1" "K07627|1|3e-16|89.0|cmk:103190990|gap junction protein, chi 1;K07612|2|8e-15|84.3|xma:102218652|gap junction protein, alpha 3;K07619|3|2e-13|80.1|myb:102244658|gap junction protein, alpha 12;K07613|5|3e-13|79.3|oas:101107643|gap junction protein, alpha 4" GO:0005921//gap junction;GO:0031224//intrinsic component of membrane - GO:0032989;GO:0043010//camera-type eye development;GO:0040007//growth gi|270047515|ref|NP_083998.1|/2.10269e-116/gap junction epsilon-1 protein [Mus musculus] 224656 2729 7.553333333 9.36 0.309395074 Up 0.442024898 Zfp523 zinc finger protein 523 K09228|1|2e-55|220|ngi:103729559|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|27369882|ref|NP_766205.1|/0/zinc finger protein 76 [Mus musculus] 56722 2240 11.7 14.12 0.271231559 Up 0.44199669 Litaf LPS-induced TN factor K19363|1|1e-69|266|mmu:56722|lipopolysaccharide-induced tumor necrosis factor-alpha factor GO:0016020//membrane;GO:0005764//lysosome GO:0060089;GO:0019904//protein domain specific binding "GO:0006351//transcription, DNA-templated;GO:0032496//response to lipopolysaccharide;GO:0012501//programmed cell death;GO:0001816//cytokine production;GO:0042345//regulation of NF-kappaB import into nucleus" gi|537141908|gb|ERE68241.1|/2.51588e-69/putative lipopolysaccharide-induced tumor necrosis factor-alpha factor like protein [Cricetulus griseus] 240327 2648 1.096666667 1.86 0.762177538 Up 0.441977886 Gm4951 predicted gene 4951 K17072|1|9e-85|317|mmu:432555|interferon gamma inducible protein 47 GO:0043231//intracellular membrane-bounded organelle;GO:0020003//symbiont-containing vacuole;GO:0031090//organelle membrane GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity GO:0007166//cell surface receptor signaling pathway;GO:0001562//response to protozoan;GO:0042742//defense response to bacterium;GO:0006914//autophagy;GO:0009154//purine ribonucleotide catabolic process;GO:0035456//response to interferon-beta gi|85702067|ref|NP_001028939.1|/0/uncharacterized protein LOC240327 [Mus musculus] 269608 3863.11 16.61666667 13.91666667 -0.255817307 Down 0.441977886 Plekhg5 "pleckstrin homology domain containing, family G (with RhoGef domain) member 5" K19464|1|0.0|1859|mmu:269608|pleckstrin homology domain-containing family G member 5 GO:0016020//membrane;GO:0044424;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0060089;GO:0008289//lipid binding GO:0019222//regulation of metabolic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0016477//cell migration;GO:0007266//Rho protein signal transduction;GO:0016477//cell migration;GO:0019222//regulation of metabolic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007266//Rho protein signal transduction gi|553237809|ref|NP_001272928.1|/0/pleckstrin homology domain-containing family G member 5 [Mus musculus] 27366 2016.1 39.13666667 45.55666667 0.219141306 Up 0.441977886 Txnl4a thioredoxin-like 4A K00670|1|5e-110|400|rno:498890|peptide alpha-N-acetyltransferase [EC:2.3.1.88] - - - - 100043040 3300 1.94 2.863333333 0.561638978 Up 0.441930874 1110002L01Rik RIKEN cDNA 1110002L01 gene - - - - "gi|148669452|gb|EDL01399.1|/2.49488e-55/mCG145864, isoform CRA_a, partial [Mus musculus]" 68180 861 1.343333333 2.156666667 0.682985873 Up 0.44183685 Hyi hydroxypyruvate isomerase (putative) K01816|1|2e-113|330|ngi:103743857|hydroxypyruvate isomerase [EC:5.3.1.22] - - - - 14227 651.38 21.03666667 24.76666667 0.235493587 Up 0.441695814 Fkbp2 FK506 binding protein 2 K09569|1|3e-71|270|ngi:103738798|FK506-binding protein 2 [EC:5.2.1.8] - - - gi|755562781|ref|XP_006526734.2|/1.59338e-81/PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP2 isoform X2 [Mus musculus] 432479 695 2.786666667 3.85 0.466318004 Up 0.4416394 4930404N11Rik RIKEN cDNA 4930404N11 gene - - - - "gi|148699471|gb|EDL31418.1|/5.83828e-125/RIKEN cDNA 4930404N11, isoform CRA_a, partial [Mus musculus]" 110351 3254.48 6.833333333 5.366666667 -0.348563221 Down 0.441629997 Rap1gap Rap1 GTPase-activating protein K17700|1|0.0|1307|rno:313644|RAP1 GTPase activating protein 1 GO:0012505//endomembrane system;GO:0044444//cytoplasmic part GO:0017111//nucleoside-triphosphatase activity;GO:0031267//small GTPase binding;GO:0060589;GO:0042802//identical protein binding GO:0043087//regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction gi|371940952|ref|NP_001243147.1|/0/rap1 GTPase-activating protein 1 isoform 2 [Mus musculus] 14792 2502 26.41 31.04666667 0.23335408 Up 0.441535974 Lpcat3 lysophosphatidylcholine acyltransferase 3 K13515|1|0.0|900|mmu:14792|lysophospholipid acyltransferase 5 [EC:2.3.1.23 2.3.1.-] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008374//O-acyltransferase activity GO:0006644//phospholipid metabolic process;GO:0050789 gi|21699058|ref|NP_660112.1|/0/lysophospholipid acyltransferase 5 [Mus musculus] 20250 5453 4.12 3.023333333 -0.446504287 Down 0.441460754 Scd2 stearoyl-Coenzyme A desaturase 2 K00507|1|0.0|754|mmu:20250|stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0046914//transition metal ion binding;GO:0016215//acyl-CoA desaturase activity GO:0008366//axon ensheathment;GO:0006631//fatty acid metabolic process gi|188219606|ref|NP_033154.2|/0/acyl-CoA desaturase 2 [Mus musculus] 68487 2614 13.60333333 16.28333333 0.259435852 Up 0.441451352 Tmem140 transmembrane protein 140 - - - - gi|37574062|ref|NP_932103.1|/1.71871e-64/transmembrane protein 140 [Mus musculus] 102466884 101 0.87 0.323333333 -1.427993154 Down 0.441235097 Mir8104 microRNA 8104 K17503|1|4e-12|72.0|pale:102891893|protein phosphatase 1H [EC:3.1.3.16] - - - gi|160358864|ref|NP_795893.2|/3.43463e-11/protein phosphatase 1H isoform 2 [Mus musculus] 69890 2858 13.74 16.41333333 0.256486257 Up 0.441188085 Zfp219 zinc finger protein 219 K09228|1|4e-18|96.7|ola:101171776|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0065007//biological regulation;GO:0006351//transcription, DNA-templated;GO:0065007//biological regulation;GO:0006351//transcription, DNA-templated;GO:0065007//biological regulation;GO:0006351//transcription, DNA-templated;GO:0065007//biological regulation" gi|225543502|ref|NP_081524.2|/0/zinc finger protein 219 isoform 1 [Mus musculus] 13009 1035 1005.856667 874.9833333 -0.201097296 Down 0.441084659 Csrp3 cysteine and glycine-rich protein 3 K09377|1|2e-117|424|cge:100761159|cysteine and glycine-rich protein GO:0043231//intracellular membrane-bounded organelle;GO:0031674//I band;GO:0043231//intracellular membrane-bounded organelle;GO:0031674//I band GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0005198//structural molecule activity GO:0006941//striated muscle contraction;GO:0008016//regulation of heart contraction;GO:0014897;GO:0007507//heart development;GO:0030239//myofibril assembly;GO:0006875//cellular metal ion homeostasis;GO:0035994//response to muscle stretch;GO:0034613//cellular protein localization;GO:0014706//striated muscle tissue development;GO:0006941//striated muscle contraction;GO:0008016//regulation of heart contraction;GO:0014897;GO:0007507//heart development;GO:0030239//myofibril assembly;GO:0006875//cellular metal ion homeostasis;GO:0035994//response to muscle stretch;GO:0034613//cellular protein localization;GO:0014706//striated muscle tissue development gi|537192590|gb|ERE77362.1|/7.77244e-119/cysteine and glycine-rich protein 3 [Cricetulus griseus] 75202 1102 2.493333333 1.63 -0.613203805 Down 0.44104705 Spaca6 sperm acrosome associated 6 - - - - gi|242332530|ref|NP_001156381.1|/0/sperm acrosome membrane-associated protein 6 precursor [Mus musculus] 70612 1606 10.26333333 12.45 0.278646376 Up 0.440962428 Tmem230 transmembrane protein 230 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|440896629|gb|ELR48511.1|/6.18503e-42/hypothetical protein M91_05180, partial [Bos mutus]" 68385 1432.12 4.323333333 5.633333333 0.381844767 Up 0.440953026 Tlcd1 TLC domain containing 1 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|21539617|ref|NP_080984.1|/2.42079e-125/calfacilitin isoform a precursor [Mus musculus] 449000 1990.82 1.2 1.976666667 0.720035198 Up 0.440887209 Zfp960 zinc finger protein 960 K09228|1|0.0|900|mmu:449000|KRAB domain-containing zinc finger protein - - - gi|255652928|ref|NP_001005358.2|/0/zinc finger protein 960 isoform 1 [Mus musculus] 75745 3584 0.94 1.656666667 0.817550689 Up 0.440859002 Rian RNA imprinted and accumulated in nucleus - - - - - 56361 1852.41 10.17 12.34333333 0.27941237 Up 0.440238444 Pus1 pseudouridine synthase 1 K06173|1|0.0|865|mmu:56361|tRNA pseudouridine38-40 synthase [EC:5.4.99.12] GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0003713//transcription coactivator activity;GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0003713//transcription coactivator activity;GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0003713//transcription coactivator activity GO:0006399//tRNA metabolic process;GO:0001522//pseudouridine synthesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0006399//tRNA metabolic process;GO:0001522//pseudouridine synthesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0006399//tRNA metabolic process;GO:0001522//pseudouridine synthesis;GO:0006366//transcription from RNA polymerase II promoter "gi|148688059|gb|EDL20006.1|/0/pseudouridine synthase 1, isoform CRA_d [Mus musculus]" 103534 2429 37.62 43.66666667 0.215032557 Up 0.44018203 Mgat4b "mannoside acetylglucosaminyltransferase 4, isoenzyme B" "K00738|1|0.0|1086|ocu:100346059|alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B [EC:2.4.1.145]" GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0008375//acetylglucosaminyltransferase activity GO:0006487//protein N-linked glycosylation "gi|655883858|ref|XP_002721364.2|/0/PREDICTED: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B [Oryctolagus cuniculus]" 53945 3380 5.616666667 4.32 -0.378682873 Down 0.440116213 Slc40a1 "solute carrier family 40 (iron-regulated transporter), member 1" "K14685|1|0.0|1054|mmu:53945|solute carrier family 40 (iron-regulated transporter), member 1" GO:0031224//intrinsic component of membrane;GO:0030136//clathrin-coated vesicle;GO:0005770//late endosome GO:0005488//binding;GO:0022890//inorganic cation transmembrane transporter activity GO:0012501//programmed cell death;GO:0009888//tissue development;GO:0048536//spleen development;GO:0006875//cellular metal ion homeostasis;GO:0006826//iron ion transport;GO:0048871//multicellular organismal homeostasis gi|124248585|ref|NP_058613.2|/0/solute carrier family 40 member 1 [Mus musculus] 21991 1601 490.2233333 563.0833333 0.199909295 Up 0.440059799 Tpi1 triosephosphate isomerase 1 K01803|1|2e-173|611|mmu:21991|triosephosphate isomerase (TIM) [EC:5.3.1.1] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses" GO:0006007//glucose catabolic process;GO:0006081//cellular aldehyde metabolic process;GO:0007275//multicellular organism development gi|226958349|ref|NP_033441.2|/1.76239e-172/triosephosphate isomerase [Mus musculus] 28199 2559.98 66.26333333 76.84 0.21364674 Up 0.440031592 Dcaf11 DDB1 and CUL4 associated factor 11 K11801|1|0.0|1049|umr:103679275|WD repeat-containing protein 23 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex - - gi|970744542|ref|XP_015105886.1|/0/PREDICTED: DDB1- and CUL4-associated factor 11 isoform X1 [Vicugna pacos] 27419 2504 4.936666667 6.326666667 0.357908352 Up 0.439852947 Naglu alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) K01205|1|0.0|1461|mmu:27419|alpha-N-acetylglucosaminidase [EC:3.2.1.50] GO:0005764//lysosome GO:0015929//hexosaminidase activity GO:0042471//ear morphogenesis;GO:0044238//primary metabolic process;GO:0044710;GO:0006026;GO:0042462//eye photoreceptor cell development;GO:0021695//cerebellar cortex development;GO:0007626//locomotory behavior;GO:0007033//vacuole organization gi|254910995|ref|NP_038820.2|/0/alpha-N-acetylglucosaminidase precursor [Mus musculus] 66061 661 4.87 3.67 -0.408141709 Down 0.439730716 Tctex1d2 Tctex1 domain containing 2 "K06085|1|3e-10|67.4|nve:NEMVE_v1g242105|synovial sarcoma, X breakpoint 2 interacting protein;K10420|2|8e-08|59.3|xtr:496911|dynein light chain Tctex-type 1" - GO:0005488//binding - gi|21426853|ref|NP_079605.1|/2.77909e-78/tctex1 domain-containing protein 2 [Mus musculus] 20170 2696 2.64 3.673333333 0.476551888 Up 0.439721313 Hps6 Hermansky-Pudlak syndrome 6 K20192|1|0.0|1521|mmu:20170|Hermansky-Pudlak syndrome 6 protein GO:0005769//early endosome - GO:0007599//hemostasis;GO:0050931//pigment cell differentiation;GO:0016043//cellular component organization gi|254939591|ref|NP_789742.2|/0/Hermansky-Pudlak syndrome 6 protein homolog [Mus musculus] 22194 1386 13.10666667 15.71 0.26138236 Up 0.439514461 Ube2e1 ubiquitin-conjugating enzyme E2E 1 K20217|1|3e-106|387|hgl:101701428|ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23] GO:0043231//intracellular membrane-bounded organelle GO:0019787//ubiquitin-like protein transferase activity;GO:0032550 GO:0006513//protein monoubiquitination;GO:0016574//histone ubiquitination;GO:0000209//protein polyubiquitination "gi|50925721|gb|AAH79134.1|/5.20107e-122/Ube2e2 protein, partial [Rattus norvegicus]" 17207 5212.13 30.60666667 26.17333333 -0.225748259 Down 0.439458047 Mcf2l mcf.2 transforming sequence-like K01530|1|0.0|797|tup:102501475|phospholipid-translocating ATPase [EC:3.6.3.1];K08810|2|3e-60|237|shr:100928424|triple functional domain protein [EC:2.7.11.1] GO:0031252//cell leading edge;GO:0044424;GO:0016020//membrane;GO:0031252//cell leading edge;GO:0044424;GO:0016020//membrane GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0035091//phosphatidylinositol binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0035091//phosphatidylinositol binding GO:0019222//regulation of metabolic process;GO:0007266//Rho protein signal transduction;GO:0006366//transcription from RNA polymerase II promoter;GO:0019222//regulation of metabolic process;GO:0007266//Rho protein signal transduction;GO:0006366//transcription from RNA polymerase II promoter gi|564389912|ref|XP_006253481.1|/0/PREDICTED: guanine nucleotide exchange factor DBS isoform X3 [Rattus norvegicus] 22384 2468.98 65.42333333 75.63666667 0.209280518 Up 0.439307608 Eif4h eukaryotic translation initiation factor 4H K03258|1|3e-18|96.7|oaa:100090195|translation initiation factor 4B - - - - 68644 1189.09 11.42666667 13.76333333 0.268425309 Up 0.439307608 Abhd14a abhydrolase domain containing 14A K13706|1|8e-119|429|mmu:68644|abhydrolase domain-containing protein 14 GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity - gi|159131878|ref|NP_001103742.1|/2.49733e-129/protein ABHD14A isoform b [Mus musculus] 20970 4972 30.16666667 25.76 -0.227822698 Down 0.439232389 Sdc3 syndecan 3 K16337|1|3e-80|303|mmu:20970|syndecan 3 GO:0043005//neuron projection;GO:0032991//macromolecular complex;GO:0031224//intrinsic component of membrane - GO:0022610 gi|37359970|dbj|BAC97963.1|/2.28161e-79/mKIAA0468 protein [Mus musculus] 13544 2953 29.60666667 25.20333333 -0.232307517 Down 0.439166573 Dvl3 dishevelled segment polarity protein 3 K02353|1|1e-173|612|bom:102280462|segment polarity protein dishevelled - - - - 16432 1773 377.5766667 432.62 0.19633075 Up 0.43915717 Itm2b integral membrane protein 2B K18264|1|7e-154|546|mmu:16432|integral membrane protein 2B GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0044421 GO:0042277//peptide binding;GO:0032550 GO:0012502//induction of programmed cell death;GO:0048731//system development;GO:0010561 gi|6680502|ref|NP_032436.1|/6.08791e-153/integral membrane protein 2B [Mus musculus] 74438 3628 2.98 4.063333333 0.447351389 Up 0.439081951 Clvs1 clavesin 1 K19625|1|1e-54|218|gja:107122767|retinaldehyde-binding protein 1 GO:0005769//early endosome;GO:0030135//coated vesicle GO:0043168//anion binding GO:0051234//establishment of localization;GO:0007033//vacuole organization gi|58037379|ref|NP_083216.1|/0/clavesin-1 [Mus musculus] 68017 1443 6.13 7.696666667 0.328346693 Up 0.43899733 Ftsj2 mitochondrial rRNA methyltransferase 2 K02427|1|4e-139|497|mmu:68017|23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166] - - - - 52323 3427 12.99333333 15.56 0.26007047 Up 0.438818684 Klhl7 kelch-like 7 K10445|1|0.0|895|mmu:52323|kelch-like protein 7 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0016020//membrane;GO:0031981//nuclear lumen;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0016020//membrane;GO:0031981//nuclear lumen GO:0042802//identical protein binding;GO:0042802//identical protein binding GO:0032446//protein modification by small protein conjugation;GO:0032446//protein modification by small protein conjugation gi|241982775|ref|NP_080724.2|/0/kelch-like protein 7 isoform 1 [Mus musculus] 24113 1233 0.846666667 0.31 -1.449525876 Down 0.438752868 Vax2 ventral anterior homeobox 2 K09318|1|2e-113|411|mmu:24113|homeobox protein ventral anterior GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0003682//chromatin binding GO:0009888//tissue development;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0048562//embryonic organ morphogenesis;GO:0043010//camera-type eye development;GO:0050953//sensory perception of light stimulus;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007420//brain development;GO:0009798//axis specification gi|6755957|ref|NP_036042.1|/1.42917e-112/ventral anterior homeobox 2 [Mus musculus] 66165 1260 25.48 29.83 0.2273987 Up 0.438687051 Bccip BRCA2 and CDKN1A interacting protein K15262|1|2e-143|511|mmu:66165|protein BCP1 GO:0043231//intracellular membrane-bounded organelle;GO:0000307//cyclin-dependent protein kinase holoenzyme complex GO:0030234//enzyme regulator activity GO:0006259//DNA metabolic process;GO:0030154//cell differentiation;GO:0033554//cellular response to stress gi|134031957|ref|NP_079668.2|/1.35639e-142/BRCA2 and CDKN1A-interacting protein [Mus musculus] 26440 1255 61.60666667 71.28666667 0.210545784 Up 0.438433187 Psma1 "proteasome (prosome, macropain) subunit, alpha type 1" K02725|1|9e-137|489|cge:100773907|20S proteasome subunit alpha 6 [EC:3.4.25.1] GO:0031981//nuclear lumen;GO:0005815//microtubule organizing center;GO:0005839//proteasome core complex;GO:0044444//cytoplasmic part;GO:0030529//intracellular ribonucleoprotein complex GO:0004175//endopeptidase activity;GO:0003676//nucleic acid binding;GO:0008289//lipid binding "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0006915//apoptotic process;GO:0044764;GO:0051320;GO:0002437//inflammatory response to antigenic stimulus;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|821015342|ref|XP_012359765.1|/2.10432e-137/PREDICTED: proteasome subunit alpha type-1 isoform X3 [Nomascus leucogenys] 66307 2563 15.62 13.07333333 -0.256767419 Down 0.438357968 Isoc1 isochorismatase domain containing 1 K04432|1|3e-11|73.6|tsp:Tsp_02206|mitogen-activated protein kinase kinase 3 [EC:2.7.12.2] GO:0042579//microbody - - gi|31541909|ref|NP_079754.2|/7.12222e-148/isochorismatase domain-containing protein 1 [Mus musculus] 50498 1187 0.466666667 1.05 1.169925001 Up 0.438320358 Ebi3 Epstein-Barr virus induced gene 3 K05059|1|8e-28|127|cmk:103183575|ciliary neurotrophic factor receptor GO:0044421 GO:0005126//cytokine receptor binding GO:0007166//cell surface receptor signaling pathway gi|7657052|ref|NP_056581.1|/1.86606e-130/interleukin-27 subunit beta precursor [Mus musculus] 13067 666 0.463333333 1.04 1.166461146 Up 0.438320358 Cyct "cytochrome c, testis" K08738|1|1e-56|221|mmu:13067|cytochrome c GO:0005740//mitochondrial envelope;GO:0044425 GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding GO:0051234//establishment of localization;GO:0012501//programmed cell death;GO:0072593//reactive oxygen species metabolic process;GO:0007154//cell communication;GO:0006091//generation of precursor metabolites and energy "gi|6753560|ref|NP_034119.1|/8.90901e-56/cytochrome c, testis-specific [Mus musculus]" 53761 6912.39 70.13666667 60.54666667 -0.21212133 Down 0.438310956 Prrc2a proline-rich coiled-coil 2A "K13219|1|1e-13|83.2|acs:100568202|splicing factor, proline- and glutamine-rich" - - - gi|312261233|ref|NP_001185973.1|/0/protein PRRC2A isoform 2 [Mus musculus] 80914 1338 39.78 34.04 -0.224812239 Down 0.438310956 Uck2 uridine-cytidine kinase 2 K00876|1|1e-143|512|mmu:80914|uridine kinase [EC:2.7.1.48] GO:0043227//membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0032550;GO:0019206//nucleoside kinase activity GO:0009611//response to wounding;GO:0070887//cellular response to chemical stimulus;GO:0006241//CTP biosynthetic process;GO:0007610//behavior;GO:0006222//UMP biosynthetic process;GO:0070646//protein modification by small protein removal gi|13507680|ref|NP_109649.1|/8.70648e-143/uridine-cytidine kinase 2 [Mus musculus] 26921 5626.7 29.27 24.95 -0.23038293 Down 0.438310956 Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 K04407|1|0.0|1139|hsa:9448|mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1] GO:0044424;GO:0044424;GO:0044424 GO:0032550;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity;GO:0032550;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity;GO:0032550;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity GO:0007254//JNK cascade;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007254//JNK cascade;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007254//JNK cascade;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process gi|755492511|ref|XP_011236832.1|/0/PREDICTED: mitogen-activated protein kinase kinase kinase kinase 4 isoform X4 [Mus musculus] 67216 2794.98 2.61 3.633333333 0.477243922 Up 0.438235737 Mboat2 membrane bound O-acyltransferase domain containing 2 K13517|1|0.0|1047|mmu:67216|lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0016411//acylglycerol O-acyltransferase activity;GO:0016411//acylglycerol O-acyltransferase activity GO:0046470//phosphatidylcholine metabolic process;GO:0046470//phosphatidylcholine metabolic process "gi|148705038|gb|EDL36985.1|/0/membrane bound O-acyltransferase domain containing 2, isoform CRA_d, partial [Mus musculus]" 72736 2418 19.46333333 22.96 0.238363832 Up 0.438207529 Tmx1 thioredoxin-related transmembrane protein 1 K16458|1|9e-33|144|hmg:100199716|centrosomal protein CEP104;K09582|2|3e-14|83.6|bfo:BRAFLDRAFT_220927|protein disulfide-isomerase A4 [EC:5.3.4.1] GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane "GO:0016667//oxidoreductase activity, acting on a sulfur group of donors" GO:0051234//establishment of localization;GO:0044710;GO:0019725//cellular homeostasis;GO:0006915//apoptotic process;GO:0006091//generation of precursor metabolites and energy "gi|148704629|gb|EDL36576.1|/5.27017e-137/thioredoxin domain containing 1, partial [Mus musculus]" 19386 9477 2.536666667 1.68 -0.59447272 Down 0.438141713 Ranbp2 RAN binding protein 2 K12172|1|0.0|5805|mmu:19386|E3 SUMO-protein ligase RanBP2 - - - gi|153792534|ref|NP_035370.2|/0/E3 SUMO-protein ligase RanBP2 [Mus musculus] 19273 5498 1.316666667 2.11 0.680352846 Up 0.437916056 Ptpru "protein tyrosine phosphatase, receptor type, U" K16662|1|0.0|2751|mmu:19273|receptor-type tyrosine-protein phosphatase U [EC:3.1.3.48] GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0031224//intrinsic component of membrane;GO:0030054//cell junction GO:0005515//protein binding;GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding;GO:0004721//phosphoprotein phosphatase activity GO:0016477//cell migration;GO:0048869//cellular developmental process;GO:0006470//protein dephosphorylation;GO:0016055//Wnt signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0034613//cellular protein localization;GO:0008283//cell proliferation;GO:0016477//cell migration;GO:0048869//cellular developmental process;GO:0006470//protein dephosphorylation;GO:0016055//Wnt signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0034613//cellular protein localization;GO:0008283//cell proliferation gi|133778922|ref|NP_001076588.1|/0/receptor-type tyrosine-protein phosphatase U isoform 2 precursor [Mus musculus] 626009 1369 3.363333333 4.503333333 0.4211015 Up 0.437906653 Gm6644 Akr1b3 pseudogene K00011|1|1e-175|618|mmu:11677|aldehyde reductase [EC:1.1.1.21] GO:0031981//nuclear lumen;GO:0044421 "GO:0016903//oxidoreductase activity, acting on the aldehyde or oxo group of donors;GO:0008106//alcohol dehydrogenase (NADP+) activity" GO:0030647;GO:0007259//JAK-STAT cascade;GO:0042221//response to chemical;GO:0006060//sorbitol metabolic process;GO:0008284//positive regulation of cell proliferation gi|148667618|gb|EDL00035.1|/2.35326e-175/mCG117541 [Mus musculus] 22403 1784 4.513333333 3.37 -0.421444742 Down 0.437906653 Wisp2 WNT1 inducible signaling pathway protein 2 K06827|1|5e-60|234|xtr:496678|connective tissue growth factor GO:0044421;GO:0016020//membrane;GO:0044424 GO:0019838//growth factor binding GO:0008283//cell proliferation;GO:0016049//cell growth;GO:0022610 gi|255683443|ref|NP_058569.2|/1.3286e-139/WNT1-inducible-signaling pathway protein 2 precursor [Mus musculus] 67371 1020 18.97333333 22.45666667 0.243170637 Up 0.437869044 Gtf3c6 "general transcription factor IIIC, polypeptide 6, alpha" K15203|1|5e-115|416|mmu:67371|general transcription factor 3C polypeptide 6 GO:0005667//transcription factor complex GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|27754091|ref|NP_080389.2|/4.32607e-114/general transcription factor 3C polypeptide 6 [Mus musculus] 67951 1807 19.28666667 22.76 0.238896735 Up 0.437709203 Tubb6 "tubulin, beta 6 class V" K07375|1|0.0|833|mmu:67951|tubulin beta GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005198//structural molecule activity GO:0009154//purine ribonucleotide catabolic process;GO:0044763;GO:0043623//cellular protein complex assembly;GO:0006458//'de novo' protein folding gi|27754056|ref|NP_080749.2|/0/tubulin beta-6 chain [Mus musculus] 244373 3951 9.003333333 7.27 -0.30850387 Down 0.437662191 Erlin2 ER lipid raft associated 2 - GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex - GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process gi|537259171|gb|ERE89622.1|/1.27541e-178/zinc finger protein [Cricetulus griseus] 13824 3853 1.65 2.503333333 0.601384383 Up 0.437286096 Epb41l4a erythrocyte membrane protein band 4.1 like 4a K18037|1|2e-71|274|sko:100367488|tyrosine-protein phosphatase non-receptor type 4 [EC:3.1.3.48] GO:0044425;GO:0043232 GO:0005515//protein binding - gi|87042272|ref|NP_038540.2|/0/band 4.1-like protein 4A [Mus musculus] 613262 1403 24.94333333 29.15333333 0.225006573 Up 0.437192072 BC029722 cDNA sequence BC029722 - - - - - 11803 2408 1.6 2.443333333 0.610778793 Up 0.437154462 Aplp1 amyloid beta (A4) precursor-like protein 1 K05639|1|0.0|1122|mmu:11803|amyloid-like protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0031690//adrenergic receptor binding;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding GO:0071870//cellular response to catecholamine stimulus;GO:0012501//programmed cell death;GO:0006412//translation;GO:0031124//mRNA 3'-end processing;GO:0022610;GO:0016192//vesicle-mediated transport;GO:0007420//brain development;GO:0006171//cAMP biosynthetic process;GO:0043062//extracellular structure organization gi|85861186|ref|NP_031493.2|/0/amyloid-like protein 1 precursor [Mus musculus] 59027 4547 39.22666667 33.69333333 -0.219371582 Down 0.437154462 Nampt nicotinamide phosphoribosyltransferase K03462|1|0.0|978|mmu:59027|nicotinamide phosphoribosyltransferase [EC:2.4.2.12] GO:0043231//intracellular membrane-bounded organelle "GO:0005102//receptor binding;GO:0042802//identical protein binding;GO:0016763//transferase activity, transferring pentosyl groups" GO:0044703;GO:0006366//transcription from RNA polymerase II promoter;GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010033//response to organic substance;GO:0048513//animal organ development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008284//positive regulation of cell proliferation "gi|148704942|gb|EDL36889.1|/0/pre-B-cell colony-enhancing factor 1, partial [Mus musculus]" 70020 1038 12.57 15.08 0.262651779 Up 0.437135658 Ino80b INO80 complex subunit B K11666|1|7e-126|452|mmu:70020|INO80 complex subunit B GO:0000790//nuclear chromatin;GO:0016020//membrane - GO:0044260;GO:0090304 gi|12963729|ref|NP_076036.1|/5.61223e-125/INO80 complex subunit B [Mus musculus] 16852 817 258.8466667 225.94 -0.196158034 Down 0.437126255 Lgals1 "lectin, galactose binding, soluble 1" K06830|1|3e-76|286|mmu:16852|galectin-1 GO:0043231//intracellular membrane-bounded organelle;GO:0044421;GO:0031012//extracellular matrix GO:0060089;GO:0097367//carbohydrate derivative binding;GO:0048030//disaccharide binding;GO:0042802//identical protein binding;GO:0048029//monosaccharide binding GO:0009611//response to wounding;GO:0007162//negative regulation of cell adhesion;GO:0010975//regulation of neuron projection development;GO:0031294//lymphocyte costimulation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0014070//response to organic cyclic compound;GO:0042692//muscle cell differentiation;GO:0001678//cellular glucose homeostasis;GO:0002313//mature B cell differentiation involved in immune response;GO:0034112//positive regulation of homotypic cell-cell adhesion gi|6678682|ref|NP_032521.1|/2.66016e-75/galectin-1 [Mus musculus] 69660 2325 32.59333333 38.09 0.224835383 Up 0.436975817 Tmbim1 transmembrane BAX inhibitor motif containing 1 K06890|1|4e-120|434|mmu:69660|uncharacterized protein GO:0005764//lysosome;GO:0031090//organelle membrane - - gi|74217818|dbj|BAE41919.1|/3.62476e-119/unnamed protein product [Mus musculus] 18641 3741 57.67333333 66.61 0.207834374 Up 0.436966415 Pfkl "phosphofructokinase, liver, B-type" K00850|1|0.0|1529|mmu:18641|6-phosphofructokinase 1 [EC:2.7.1.11] GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0032550;GO:0008443//phosphofructokinase activity;GO:0043169//cation binding;GO:0043168//anion binding;GO:0050308//sugar-phosphatase activity;GO:0048029//monosaccharide binding;GO:0019899//enzyme binding GO:0006007//glucose catabolic process;GO:0016310//phosphorylation;GO:0050796//regulation of insulin secretion;GO:0009746;GO:0051260//protein homooligomerization "gi|31560653|ref|NP_032852.2|/0/ATP-dependent 6-phosphofructokinase, liver type [Mus musculus]" 67513 1519 4.023333333 5.256666667 0.385756984 Up 0.43694761 Faap20 Fanconi anemia core complex associated protein 20 - - - - - 238393 2042 0.553333333 1.15 1.05541312 Up 0.436938208 Serpina3f "serine (or cysteine) peptidase inhibitor, clade A, member 3F" "K04525|1|0.0|861|mmu:238393|serpin peptidase inhibitor, clade A" - - - gi|269973844|ref|NP_001161767.1|/0/serine protease inhibitor A3F [Mus musculus] 18186 5921 18.33333333 15.45 -0.24686228 Down 0.436759562 Nrp1 neuropilin 1 K06724|1|0.0|1766|mmu:18186|neuropilin 1 GO:0043005//neuron projection;GO:0044297//cell body;GO:0005882//intermediate filament;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0043169//cation binding;GO:0005539//glycosaminoglycan binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity GO:0001934//positive regulation of protein phosphorylation;GO:0001525//angiogenesis;GO:0035728//response to hepatocyte growth factor;GO:0043542//endothelial cell migration;GO:0060445//branching involved in salivary gland morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0022610;GO:0006935//chemotaxis;GO:0021559//trigeminal nerve development;GO:0048483//autonomic nervous system development;GO:0030517//negative regulation of axon extension;GO:0006950//response to stress gi|244792700|ref|NP_032763.2|/0/neuropilin-1 precursor [Mus musculus] 83679 8393.58 230.8733333 200.32 -0.204795079 Down 0.43675016 Pde4dip phosphodiesterase 4D interacting protein (myomegalin) K16549|1|0.0|4061|mmu:83679|myomegalin GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0043292//contractile fiber;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0043292//contractile fiber;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0043292//contractile fiber GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0006461//protein complex assembly;GO:0006461//protein complex assembly;GO:0006461//protein complex assembly gi|576067819|ref|NP_001276630.1|/0/myomegalin isoform 5 [Mus musculus] 110606 2560 8.773333333 10.70333333 0.286863176 Up 0.436740757 Fntb "farnesyltransferase, CAAX box, beta" K05954|1|0.0|895|mmu:110606|protein farnesyltransferase subunit beta [EC:2.5.1.58] GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton GO:0046914//transition metal ion binding;GO:0008289//lipid binding;GO:0008318//protein prenyltransferase activity;GO:0033218//amide binding GO:0018342//protein prenylation;GO:0051726//regulation of cell cycle;GO:0009611//response to wounding;GO:0008284//positive regulation of cell proliferation;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010033//response to organic substance "gi|148704499|gb|EDL36446.1|/0/mCG7924, partial [Mus musculus]" 73474 183 0.01 0.333333333 5.058893689 Up 0.436618526 Snhg9 small nucleolar RNA host gene 9 - - - - - 668108 3418 0.33 0.01 -5.044394119 Down 0.436618526 Gm8979 very large inducible GTPase 1 pseudogene - - - - gi|148684884|gb|EDL16831.1|/0/mCG127513 [Mus musculus] 68346 1369 27.57333333 23.44666667 -0.233890851 Down 0.436364662 Sirt5 sirtuin 5 K11415|1|0.0|645|mmu:68346|NAD-dependent deacetylase sirtuin 5 [EC:3.5.1.-] GO:0005740//mitochondrial envelope "GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0046914//transition metal ion binding;GO:0043168//anion binding" GO:0035601//protein deacylation;GO:0018205//peptidyl-lysine modification "gi|30578432|ref|NP_849179.1|/0/NAD-dependent protein deacylase sirtuin-5, mitochondrial [Mus musculus]" 70772 1231.85 9.54 7.74 -0.3016557 Down 0.43635526 Ggnbp1 gametogenetin binding protein 1 K11835|1|6e-08|61.6|mze:101478314|ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.4.19.12] GO:0005740//mitochondrial envelope;GO:0016020//membrane;GO:0005740//mitochondrial envelope;GO:0016020//membrane GO:0005488//binding;GO:0005488//binding GO:0007005//mitochondrion organization;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0007005//mitochondrion organization;GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|353523860|ref|NP_001238810.1|/7.56071e-147/gametogenetin-binding protein 1 isoform b [Mus musculus] 545641 1078 3.963333333 2.9 -0.450661409 Down 0.43631765 Gm5860 predicted gene 5860 - - - - - 20359 3847 8.543333333 10.46 0.292011874 Up 0.436289443 Sema6b "sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B" K06842|1|0.0|1503|mmu:20359|semaphorin 6 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005102//receptor binding;GO:0005102//receptor binding GO:0048731//system development;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0048869//cellular developmental process gi|7305475|ref|NP_038690.1|/0/semaphorin-6B precursor [Mus musculus] 67006 2885 18.61666667 21.98666667 0.240034118 Up 0.436270638 Cisd2 CDGSH iron sulfur domain 2 - GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0031966//mitochondrial membrane GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0042802//identical protein binding GO:0007275//multicellular organism development;GO:0006914//autophagy gi|21728370|ref|NP_080178.1|/1.21076e-58/CDGSH iron-sulfur domain-containing protein 2 [Mus musculus] 546143 722 5.09 6.486666667 0.349811648 Up 0.43615781 Ccpg1os "cell cycle progression 1, opposite strand" - - - - gi|311771684|ref|NP_001185718.1|/7.85013e-67/uncharacterized protein C15orf65 homolog [Mus musculus] 56209 1529 32.79 38.14666667 0.218301095 Up 0.436139005 Gde1 glycerophosphodiester phosphodiesterase 1 K19179|1|0.0|667|mmu:56209|glycerophosphoinositol glycerophosphodiesterase [EC:3.1.4.44] GO:0016021//integral component of membrane GO:0043169//cation binding;GO:0008081//phosphoric diester hydrolase activity GO:0019400;GO:0007166//cell surface receptor signaling pathway gi|9625018|ref|NP_062526.1|/0/glycerophosphodiester phosphodiesterase 1 [Mus musculus] 20823 2061 11.68333333 9.61 -0.281843607 Down 0.4361202 Ssb Sjogren syndrome antigen B K11090|1|0.0|759|mmu:20823|lupus La protein GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding GO:0006399//tRNA metabolic process;GO:0010467//gene expression;GO:0006399//tRNA metabolic process;GO:0010467//gene expression "gi|148695104|gb|EDL27051.1|/0/Sjogren syndrome antigen B, isoform CRA_b, partial [Mus musculus]" 319164 487 0.01 0.326666667 5.029747343 Up 0.436073188 Hist1h2ac "histone cluster 1, H2ac" K11251|1|5e-55|214|ocu:100348744|histone H2A;K11254|2|2e-54|213|chx:102181082|histone H4 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|655839886|ref|XP_002714260.2|/3.29712e-54/PREDICTED: histone H2A type 1-like [Oryctolagus cuniculus] 545007 1815 0.326666667 0.01 -5.029747343 Down 0.436073188 Gm5796 predicted gene 5796 "K03844|1|2e-16|89.7|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - - 208285 1693 1.463333333 2.276666667 0.637664639 Up 0.435988567 Cyp4f17 "cytochrome P450, family 4, subfamily f, polypeptide 17" "K00490|1|0.0|1095|mmu:208285|cytochrome P450, family 4, subfamily F [EC:1.14.14.1];K17726|4|0.0|897|rno:266689|leukotriene-B4 20-monooxygenase / phylloquinone omega-hydroxylase [EC:1.14.13.30 1.14.13.194]" GO:0031090//organelle membrane "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0006952//defense response;GO:0006690//icosanoid metabolic process "gi|168229218|ref|NP_001094915.1|/0/cytochrome P450, family 4, subfamily f, polypeptide 17 precursor [Mus musculus]" 239796 3080 3.883333333 5.1 0.393201698 Up 0.435950957 Mb21d2 Mab-21 domain containing 2 K04358|1|2e-33|147|cfa:607829|fibroblast growth factor;K16271|2|7e-20|102|chx:102190496|E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27];K17834|4|5e-07|59.7|crg:105322106|cyclic GMP-AMP synthase [EC:2.7.7.86] - - - gi|86262157|ref|NP_808386.2|/0/protein MB21D2 [Mus musculus] 230696 1867 3.65 2.633333333 -0.471006311 Down 0.435950957 AU022252 expressed sequence AU022252 - - - - gi|59958368|ref|NP_001012400.1|/1.12923e-104/uncharacterized protein C1orf50 homolog [Mus musculus] 75452 2623 10.57 8.66 -0.287536447 Down 0.435838129 Ascc2 activating signal cointegrator 1 complex subunit 2 K18667|1|0.0|1390|mmu:75452|activating signal cointegrator complex subunit 2 - - "GO:0006351//transcription, DNA-templated" gi|20270208|ref|NP_083567.1|/0/activating signal cointegrator 1 complex subunit 2 [Mus musculus] 68510 7133 14.72666667 12.26333333 -0.264079742 Down 0.435838129 Ints1 integrator complex subunit 1 K13138|1|0.0|3937|mmu:68510|integrator complex subunit 1 - - - gi|294832004|ref|NP_081024.3|/0/integrator complex subunit 1 [Mus musculus] 212114 1560 1.79 1.056666667 -0.760439248 Down 0.435678288 Nhlrc3 NHL repeat containing 3 K18200|1|2e-14|83.2|bfo:BRAFLDRAFT_127740|peptidylamidoglycolate lyase [EC:4.3.2.5];K00504|2|7e-12|74.7|cin:100186640|peptidylglycine monooxygenase [EC:1.14.17.3] - - - "gi|149064803|gb|EDM14954.1|/0/rCG49974, isoform CRA_b [Rattus norvegicus]" 69955 1896 32.41 37.66333333 0.216721668 Up 0.435518447 Fars2 phenylalanine-tRNA synthetase 2 (mitochondrial) K01889|1|0.0|934|mmu:69955|phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] GO:0044429;GO:0044429 GO:0003723//RNA binding;GO:0032550;GO:0046872//metal ion binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0003723//RNA binding;GO:0032550;GO:0046872//metal ion binding;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation "gi|22267456|ref|NP_077236.1|/0/phenylalanine--tRNA ligase, mitochondrial isoform 1 [Mus musculus]" 330260 1850 23.48 27.52666667 0.229397509 Up 0.435499643 Pon2 paraoxonase 2 K01045|1|0.0|689|mmu:330260|arylesterase / paraoxonase [EC:3.1.1.2 3.1.8.1] GO:0000323//lytic vacuole;GO:0016020//membrane GO:0043169//cation binding;GO:0005515//protein binding;GO:0052689//carboxylic ester hydrolase activity GO:0006725//cellular aromatic compound metabolic process;GO:0006950//response to stress gi|34303979|ref|NP_899131.1|/0/serum paraoxonase/arylesterase 2 [Mus musculus] 406218 3434 0.416666667 0.973333333 1.224040274 Up 0.435471436 Panx2 pannexin 2 K03443|1|0.0|1155|mmu:406218|pannexin - - - gi|163838635|ref|NP_001002005.2|/0/pannexin-2 [Mus musculus] 17775 2130 166.61 191.03 0.197324227 Up 0.435339802 Laptm4a lysosomal-associated protein transmembrane 4A K12387|1|5e-143|510|mmu:17775|lysosomal-associated transmembrane protein GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0051234//establishment of localization gi|109689716|ref|NP_032666.2|/4.65641e-142/lysosomal-associated transmembrane protein 4A [Mus musculus] 11833 1483 1.686666667 0.976666667 -0.78823672 Down 0.435142352 Aqp8 aquaporin 8 K09869|1|5e-132|473|mmu:11833|aquaporin-8 GO:0016021//integral component of membrane;GO:0043227//membrane-bounded organelle;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0043227//membrane-bounded organelle;GO:0016324//apical plasma membrane GO:0005372//water transmembrane transporter activity;GO:0005372//water transmembrane transporter activity GO:0015721//bile acid and bile salt transport;GO:0044763;GO:0051591//response to cAMP;GO:0042044//fluid transport;GO:0015721//bile acid and bile salt transport;GO:0044763;GO:0051591//response to cAMP;GO:0042044//fluid transport gi|6680714|ref|NP_031500.1|/3.98138e-131/aquaporin-8 isoform 1 [Mus musculus] 56790 1968 3.923333333 2.876666667 -0.447681856 Down 0.435029523 Supt20 suppressor of Ty 20 - - - - - 15957 2638 2.853333333 3.906666667 0.453289868 Up 0.435029523 Ifit1 interferon-induced protein with tetratricopeptide repeats 1 K14217|1|0.0|881|mmu:15957|interferon-induced protein with tetratricopeptide repeats 1 GO:0044424 GO:0005488//binding GO:0019079//viral genome replication;GO:0051095;GO:0043393//regulation of protein binding;GO:0034340//response to type I interferon;GO:0050687//negative regulation of defense response to virus;GO:0043330//response to exogenous dsRNA;GO:0035455//response to interferon-alpha;GO:0035456//response to interferon-beta gi|110626104|ref|NP_032357.2|/0/interferon-induced protein with tetratricopeptide repeats 1 [Mus musculus] 78267 2953 2.736666667 1.86 -0.5571171 Down 0.435020121 Klhdc8b kelch domain containing 8B K10446|1|3e-20|103|spu:575182|kelch-like protein 8 GO:0044424 - - "gi|148689341|gb|EDL21288.1|/0/kelch domain containing 8B, isoform CRA_b, partial [Mus musculus]" 16186 1655.88 9.53 11.57333333 0.280256328 Up 0.434973109 Il2rg "interleukin 2 receptor, gamma chain" K05070|1|0.0|693|mmu:16186|interleukin 2 receptor gamma GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface GO:0004888//transmembrane signaling receptor activity;GO:0019838//growth factor binding;GO:0004888//transmembrane signaling receptor activity;GO:0019838//growth factor binding "GO:0002361//CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0033077//T cell differentiation in thymus;GO:0030183//B cell differentiation;GO:0010467//gene expression;GO:0002361//CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0033077//T cell differentiation in thymus;GO:0030183//B cell differentiation;GO:0010467//gene expression" gi|7305181|ref|NP_038591.1|/2.6382e-169/cytokine receptor common subunit gamma isoform a precursor [Mus musculus] 94315 2090 30.94 36.11333333 0.223058393 Up 0.434860281 Prcc papillary renal cell carcinoma (translocation-associated) K13105|1|1e-152|543|mmu:94315|proline-rich protein PRCC GO:0031981//nuclear lumen - GO:0000075//cell cycle checkpoint gi|15809012|ref|NP_291051.1|/8.30727e-152/proline-rich protein PRCC [Mus musculus] 68016 2062 58.87666667 50.84333333 -0.211637377 Down 0.434728647 Murc muscle-related coiled-coil protein K19387|1|4e-39|165|pss:102460644|polymerase I and transcript release factor GO:0031674//I band - GO:0007265//Ras protein signal transduction;GO:0030239//myofibril assembly;GO:0048513//animal organ development;GO:0006366//transcription from RNA polymerase II promoter gi|225543548|ref|NP_080785.2|/0/muscle-related coiled-coil protein [Mus musculus] 67604 2106 17.73333333 20.99666667 0.243696565 Up 0.434540599 Get4 golgi to ER traffic protein 4 - - - - - 74766 1944.81 31.16333333 36.23666667 0.217600694 Up 0.434296138 Yipf2 "Yip1 domain family, member 2" - "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031224//intrinsic component of membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031224//intrinsic component of membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031224//intrinsic component of membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031224//intrinsic component of membrane" - - "gi|148693256|gb|EDL25203.1|/4.45029e-160/Yip1 domain family, member 2, isoform CRA_b, partial [Mus musculus]" 109910 5624 26.43 22.48666667 -0.233106607 Down 0.434286735 Zfp91 zinc finger protein 91 K04961|1|8e-147|525|ocu:103351584|ryanodine receptor 1;K09228|2|1e-21|109|xma:102228377|KRAB domain-containing zinc finger protein - - - gi|90669983|ref|NP_443735.2|/0/E3 ubiquitin-protein ligase ZFP91 [Mus musculus] 68401 1612 30.67 35.73333333 0.220442333 Up 0.434239723 G6pc3 "glucose 6 phosphatase, catalytic, 3" K01084|1|0.0|691|mmu:68401|glucose-6-phosphatase [EC:3.1.3.9] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0050309 GO:0015712//hexose phosphate transport;GO:0006796//phosphate-containing compound metabolic process;GO:0006006//glucose metabolic process gi|47271524|ref|NP_787949.2|/0/glucose-6-phosphatase 3 [Mus musculus] 56350 838 50.66 58.48 0.207096234 Up 0.434220918 Arl3 ADP-ribosylation factor-like 3 K07944|1|1e-80|301|cge:100757638|ADP-ribosylation factor-like protein 3 GO:0031981//nuclear lumen;GO:0031513//nonmotile primary cilium;GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0005874//microtubule;GO:0005819//spindle;GO:0012505//endomembrane system GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0043169//cation binding;GO:0015631//tubulin binding GO:0010970//transport along microtubule;GO:0045184//establishment of protein localization;GO:0046530//photoreceptor cell differentiation;GO:0048858//cell projection morphogenesis;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction gi|831221395|ref|XP_012658993.1|/9.91357e-81/PREDICTED: ADP-ribosylation factor-like protein 3 [Otolemur garnettii] 14979 981 48.52333333 56.3 0.214456262 Up 0.434155102 H2-Ke6 H2-K region expressed gene 6 K13370|1|1e-105|385|mmu:14979|17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239] GO:0031967;GO:0044429;GO:0016020//membrane "GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0006631//fatty acid metabolic process;GO:0006694//steroid biosynthetic process gi|157951743|ref|NP_038571.2|/9.92505e-105/estradiol 17-beta-dehydrogenase 8 [Mus musculus] 19139 1998 12.41333333 14.81666667 0.255330346 Up 0.43410809 Prps1 phosphoribosyl pyrophosphate synthetase 1 K00948|1|1e-178|629|pale:102893258|ribose-phosphate pyrophosphokinase [EC:2.7.6.1] GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0032550;GO:0016778;GO:0046872//metal ion binding;GO:0042802//identical protein binding GO:0006220//pyrimidine nucleotide metabolic process;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0009152//purine ribonucleotide biosynthetic process;GO:0044283//small molecule biosynthetic process;GO:0009887//organ morphogenesis;GO:0009113//purine nucleobase biosynthetic process "gi|440900332|gb|ELR51492.1|/2.85765e-178/Ribose-phosphate pyrophosphokinase 1, partial [Bos mutus]" 109731 2428 26.21 22.29333333 -0.233505007 Down 0.434098687 Maob monoamine oxidase B K00274|1|0.0|1019|mmu:109731|monoamine oxidase [EC:1.4.3.4] GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane "GO:0000166//nucleotide binding;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0042802//identical protein binding" GO:0042053//regulation of dopamine metabolic process;GO:0051384//response to glucocorticoid;GO:0042133//neurotransmitter metabolic process;GO:0010038//response to metal ion;GO:0097305//response to alcohol;GO:0002237//response to molecule of bacterial origin;GO:0001820//serotonin secretion gi|257196228|ref|NP_766366.2|/0/amine oxidase [flavin-containing] B [Mus musculus] 69816 928 0.546666667 1.14 1.06030051 Up 0.43407048 Mzb1 marginal zone B and B1 cell-specific protein 1 "K14611|1|1e-11|72.8|tgu:100231186|solute carrier family 23 (nucleobase transporter), member 1/2;K15410|2|7e-09|63.5|hro:HELRODRAFT_194214|elongation factor 1-delta" GO:0044432;GO:0043234//protein complex GO:0005488//binding GO:0002378//immunoglobulin biosynthetic process;GO:0006461//protein complex assembly;GO:0046325//negative regulation of glucose import;GO:0042100//B cell proliferation gi|257467474|ref|NP_081498.2|/1.35777e-100/marginal zone B- and B1-cell-specific protein precursor [Mus musculus] 67178 789 17.79666667 21.03 0.240841802 Up 0.434042273 Zmat5 "zinc finger, matrin type 5" K13152|1|9e-100|365|mmu:67178|U11/U12 small nuclear ribonucleoprotein 20 kDa protein GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0006396//RNA processing gi|13385520|ref|NP_080291.1|/7.16214e-99/zinc finger matrin-type protein 5 [Mus musculus] 319587 510 3.06 2.14 -0.515920856 Down 0.433985859 4930539J05Rik RIKEN cDNA 4930539J05 gene - - - - - 72287 1559 10.45333333 12.63 0.27289158 Up 0.433816616 Plekhf1 "pleckstrin homology domain containing, family F (with FYVE domain) member 1" "K05724|1|1e-27|127|hgl:101708057|FYVE, RhoGEF and PH domain containing 5/6" GO:0005764//lysosome;GO:0031981//nuclear lumen;GO:0031090//organelle membrane GO:1901981//phosphatidylinositol phosphate binding;GO:0043169//cation binding GO:0012502//induction of programmed cell death;GO:0006996//organelle organization;GO:0007009//plasma membrane organization;GO:0006914//autophagy "gi|148671039|gb|EDL02986.1|/1.83157e-142/mCG3157, isoform CRA_a, partial [Mus musculus]" 22330 5229 35.67333333 30.68333333 -0.217390807 Down 0.433741397 Vcl vinculin K05700|1|0.0|1886|mmu:22330|vinculin GO:0032991//macromolecular complex;GO:0005913//cell-cell adherens junction;GO:0005924//cell-substrate adherens junction;GO:0031674//I band;GO:0044291//cell-cell contact zone;GO:0032432//actin filament bundle;GO:0005886//plasma membrane GO:0008092//cytoskeletal protein binding;GO:0017016//Ras GTPase binding;GO:0001948//glycoprotein binding GO:0016477//cell migration;GO:0007043//cell-cell junction assembly;GO:0016337//single organismal cell-cell adhesion;GO:0048729//tissue morphogenesis;GO:0034613//cellular protein localization;GO:0030031//cell projection assembly gi|31543942|ref|NP_033528.3|/0/vinculin [Mus musculus] 68147 1271 4.29 5.56 0.374107235 Up 0.433637971 Gar1 GAR1 ribonucleoprotein K11128|1|3e-51|205|mmu:68147|H/ACA ribonucleoprotein complex subunit 1 - - - - 13867 4020 2.39 1.57 -0.606246059 Down 0.433562752 Erbb3 erb-b2 receptor tyrosine kinase 3 K05084|1|0.0|2553|mmu:13867|receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1] - - - - 18578 3932.98 5.78 7.273333333 0.331547203 Up 0.433459325 Pde4b "phosphodiesterase 4B, cAMP specific" K13293|1|4e-104|380|rno:24626|cAMP-specific phosphodiesterase 4 [EC:3.1.4.53] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity" GO:0046058//cAMP metabolic process;GO:0042493//response to drug;GO:0001776//leukocyte homeostasis;GO:0007154//cell communication;GO:0032496//response to lipopolysaccharide;GO:0030595//leukocyte chemotaxis;GO:0006936//muscle contraction;GO:0046058//cAMP metabolic process;GO:0042493//response to drug;GO:0001776//leukocyte homeostasis;GO:0007154//cell communication;GO:0032496//response to lipopolysaccharide;GO:0030595//leukocyte chemotaxis;GO:0006936//muscle contraction;GO:0046058//cAMP metabolic process;GO:0042493//response to drug;GO:0007154//cell communication;GO:0032496//response to lipopolysaccharide;GO:0030595//leukocyte chemotaxis;GO:0006936//muscle contraction;GO:0046058//cAMP metabolic process;GO:0042493//response to drug;GO:0032496//response to lipopolysaccharide;GO:0030595//leukocyte chemotaxis;GO:0006936//muscle contraction;GO:0046058//cAMP metabolic process;GO:0042493//response to drug;GO:0001776//leukocyte homeostasis;GO:0007154//cell communication;GO:0032496//response to lipopolysaccharide;GO:0030595//leukocyte chemotaxis;GO:0006936//muscle contraction "gi|568928609|ref|XP_006502920.1|/0/PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X3 [Mus musculus]" 13685 981 149.8766667 130.7133333 -0.197369487 Down 0.433449923 Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 K07205|1|3e-62|241|mmu:13685|eukaryotic translation initiation factor 4E binding protein 1 GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part GO:0045182//translation regulator activity;GO:0031369//translation initiation factor binding GO:0006413//translational initiation;GO:0044772//mitotic cell cycle phase transition;GO:0006461//protein complex assembly;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030323//respiratory tube development;GO:0097305//response to alcohol;GO:0035556//intracellular signal transduction gi|122937368|ref|NP_031944.3|/2.31479e-61/eukaryotic translation initiation factor 4E-binding protein 1 [Mus musculus] 56473 1508 3.003333333 4.063333333 0.436099115 Up 0.433440521 Fads2 fatty acid desaturase 2 K10226|1|0.0|929|mmu:56473|acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016215//acyl-CoA desaturase activity GO:0000038//very long-chain fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization gi|9790071|ref|NP_062673.1|/0/fatty acid desaturase 2 [Mus musculus] 18451 4057 14.14 16.87 0.254677853 Up 0.433421716 P4ha1 "procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide" K00472|1|0.0|1053|mmu:18451|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0044432 "GO:0019842//vitamin binding;GO:0046914//transition metal ion binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0019798//procollagen-proline dioxygenase activity" GO:0019471//4-hydroxyproline metabolic process;GO:0030198//extracellular matrix organization gi|74225936|dbj|BAE28745.1|/0/unnamed protein product [Mus musculus] 277743 1460 1.113333333 1.85 0.732639669 Up 0.433402911 Fam131c "family with sequence similarity 131, member C" K03260|1|2e-23|113|shr:100933156|translation initiation factor 4G - - - gi|148222952|ref|NP_001078982.1|/1.04895e-152/protein FAM131C [Mus musculus] 654467 1428 49.07 56.57333333 0.205280907 Up 0.433393509 Gm10052 heterogeneous nuclear ribonucleoprotein A1 pseudogene K12741|1|2e-107|391|shr:100919352|heterogeneous nuclear ribonucleoprotein A1/A3 GO:0005681//spliceosomal complex;GO:0005856//cytoskeleton;GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0036094//small molecule binding;GO:0043566//structure-specific DNA binding "GO:0050658//RNA transport;GO:0000398//mRNA splicing, via spliceosome;GO:0006913//nucleocytoplasmic transport" "gi|148671985|gb|EDL03932.1|/2.8871e-115/mCG15678, isoform CRA_c, partial [Mus musculus]" 58810 1435 125.2666667 143.83 0.199362058 Up 0.43324307 Akr1a1 "aldo-keto reductase family 1, member A1 (aldehyde reductase)" K00002|1|0.0|635|mmu:58810|alcohol dehydrogenase (NADP+) [EC:1.1.1.2] - - - - 170706 1017 2.62 3.623333333 0.467750723 Up 0.433158449 Tmem37 transmembrane protein 37 - GO:0031224//intrinsic component of membrane GO:0005261//cation channel activity GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport gi|9506457|ref|NP_062305.1|/5.26155e-112/voltage-dependent calcium channel gamma-like subunit [Mus musculus] 56484 2889 14.13 11.77 -0.263647145 Down 0.432970401 Foxo3 forkhead box O3 K09408|1|0.0|974|mmu:56484|forkhead box protein O3 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0001541//ovarian follicle development;GO:0006366//transcription from RNA polymerase II promoter;GO:0033500//carbohydrate homeostasis;GO:0006412//translation;GO:0042770//signal transduction in response to DNA damage;GO:0006355//regulation of transcription, DNA-templated;GO:0012502//induction of programmed cell death;GO:0030218//erythrocyte differentiation" gi|9789951|ref|NP_062714.1|/0/forkhead box protein O3 [Mus musculus] 675325 1511 2.393333333 3.353333333 0.486574556 Up 0.432960999 2410017I17Rik RIKEN cDNA 2410017I17 gene "K06751|1|1e-29|129|mmu:15015|major histocompatibility complex, class I" - - - gi|26350019|dbj|BAC38649.1|/3.59272e-103/unnamed protein product [Mus musculus] 216613 5340 4.56 3.423333333 -0.413632049 Down 0.432960999 Ccdc85a coiled-coil domain containing 85A K16758|1|9e-24|116|xma:102228104|coiled-coil domain-containing protein 85B - - - gi|50511181|dbj|BAD32576.1|/0/mKIAA1912 protein [Mus musculus] 12390 2748 11.13666667 9.146666667 -0.283999501 Down 0.432810561 Cav2 caveolin 2 K12958|1|1e-89|333|mmu:12390|caveolin 2 GO:0001669//acrosomal vesicle;GO:0032991//macromolecular complex;GO:0016021//integral component of membrane;GO:0012505//endomembrane system;GO:0005783//endoplasmic reticulum;GO:0009898//cytoplasmic side of plasma membrane;GO:0001669//acrosomal vesicle;GO:0032991//macromolecular complex;GO:0016021//integral component of membrane;GO:0012505//endomembrane system;GO:0005783//endoplasmic reticulum;GO:0009898//cytoplasmic side of plasma membrane GO:0000149//SNARE binding;GO:0042802//identical protein binding;GO:0050780//dopamine receptor binding;GO:0000149//SNARE binding;GO:0042802//identical protein binding;GO:0050780//dopamine receptor binding GO:0007267//cell-cell signaling;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006461//protein complex assembly;GO:0001935//endothelial cell proliferation;GO:0001765//membrane raft assembly;GO:0007212//dopamine receptor signaling pathway;GO:0016192//vesicle-mediated transport;GO:0007067//mitotic nuclear division;GO:0007519//skeletal muscle tissue development;GO:0007267//cell-cell signaling;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006461//protein complex assembly;GO:0001935//endothelial cell proliferation;GO:0001765//membrane raft assembly;GO:0007212//dopamine receptor signaling pathway;GO:0016192//vesicle-mediated transport;GO:0007067//mitotic nuclear division;GO:0007519//skeletal muscle tissue development gi|18702317|ref|NP_058596.1|/1.05894e-88/caveolin-2 isoform 1 [Mus musculus] 69727 3225 6.336666667 4.976666667 -0.348544367 Down 0.432782354 Usp46 ubiquitin specific peptidase 46 K11842|1|0.0|708|lve:103074221|ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12] - GO:0019783//ubiquitin-like protein-specific protease activity;GO:0005488//binding;GO:0016790//thiolester hydrolase activity GO:0070646//protein modification by small protein removal;GO:0050896//response to stimulus;GO:0019941//modification-dependent protein catabolic process;GO:0050804//modulation of synaptic transmission gi|29243896|ref|NP_808229.1|/0/ubiquitin carboxyl-terminal hydrolase 46 [Mus musculus] 16890 2832.18 46.42 53.74 0.211249799 Up 0.432744744 Lipe "lipase, hormone sensitive" K07188|1|0.0|1409|mmu:16890|hormone-sensitive lipase [EC:3.1.1.79] GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044444//cytoplasmic part;GO:0044421;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044444//cytoplasmic part;GO:0044421 GO:0016298//lipase activity;GO:0019900//kinase binding;GO:0019843//rRNA binding;GO:0052689//carboxylic ester hydrolase activity;GO:0016298//lipase activity;GO:0019900//kinase binding;GO:0019843//rRNA binding;GO:0052689//carboxylic ester hydrolase activity GO:0044703;GO:0006641//triglyceride metabolic process;GO:0006360//transcription from RNA polymerase I promoter;GO:0016125//sterol metabolic process;GO:0042221//response to chemical;GO:0046339//diacylglycerol metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0044703;GO:0006641//triglyceride metabolic process;GO:0006360//transcription from RNA polymerase I promoter;GO:0016125//sterol metabolic process;GO:0042221//response to chemical;GO:0046339//diacylglycerol metabolic process;GO:0001676//long-chain fatty acid metabolic process gi|87239970|ref|NP_034849.2|/0/hormone-sensitive lipase isoform 1 [Mus musculus] 21803 2191 29 33.84333333 0.222818771 Up 0.432613111 Tgfb1 "transforming growth factor, beta 1" K13375|1|0.0|729|mmu:21803|transforming growth factor beta-1 - - - - 20668 3547 10.23 8.393333333 -0.285490363 Down 0.432594306 Sox13 SRY (sex determining region Y)-box 13 K09269|1|0.0|1071|mmu:20668|transcription factor SOX5/6/13 (SOX group D) GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated" gi|2764544|emb|CAA04278.1|/0/HMG-box transcription factor [Mus musculus] 11852 2264 113.94 131.2666667 0.204226299 Up 0.432584904 Rhob ras homolog family member B "K07856|1|3e-116|408|tup:102471564|Ras homolog gene family, member B" GO:0005770//late endosome;GO:0032155;GO:0031090//organelle membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0001525//angiogenesis;GO:0007265//Ras protein signal transduction;GO:0007599//hemostasis;GO:0034614//cellular response to reactive oxygen species;GO:0007041//lysosomal transport;GO:0022610;GO:0051726//regulation of cell cycle;GO:0045184//establishment of protein localization;GO:0048869//cellular developmental process;GO:0006935//chemotaxis;GO:0009154//purine ribonucleotide catabolic process;GO:0010212//response to ionizing radiation;GO:0001775//cell activation;GO:0000910//cytokinesis gi|562880169|ref|XP_006172283.1|/2.46776e-115/PREDICTED: LOW QUALITY PROTEIN: rho-related GTP-binding protein RhoB [Tupaia chinensis] 234595 3282 7.363333333 9.09 0.303921282 Up 0.432566099 Slc38a7 "solute carrier family 38, member 7" "K14994|1|0.0|856|mmu:234595|solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 7/8" GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0044297//cell body GO:0008324//cation transmembrane transporter activity;GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity GO:0015740//C4-dicarboxylate transport;GO:0030001//metal ion transport;GO:0015807//L-amino acid transport "gi|148679241|gb|EDL11188.1|/0/cDNA sequence BC031853, isoform CRA_b [Mus musculus]" 211151 672 45.89 53.14 0.211618421 Up 0.432547294 Churc1 churchill domain containing 1 K05954|1|2e-30|134|cjo:107314159|protein farnesyltransferase subunit beta [EC:2.5.1.58] - GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|197099170|ref|NP_001126496.1|/1.71119e-62/protein Churchill [Pongo abelii] 225791 3321 20.22666667 17.08666667 -0.243387607 Down 0.432387453 Zadh2 "zinc binding alcohol dehydrogenase, domain containing 2" K07119|1|0.0|697|mmu:225791|uncharacterized protein GO:0042579//microbody GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0003824//catalytic activity GO:0044710 gi|31559926|ref|NP_666202.2|/0/zinc-binding alcohol dehydrogenase domain-containing protein 2 [Mus musculus] 216961 1416 129.3966667 112.74 -0.198800981 Down 0.432274625 Coro6 coronin 6 K13886|1|0.0|831|cge:100756161|coronin-1B/1C/6 GO:0005856//cytoskeleton GO:0003779//actin binding GO:0007010//cytoskeleton organization gi|41281703|ref|NP_624356.1|/0/coronin-6 isoform B [Mus musculus] 20409 1714 17.25666667 20.37666667 0.239764249 Up 0.432124187 Ostf1 osteoclast stimulating factor 1 K20175|1|8e-12|74.7|ola:101165459|ankyrin repeat domain-containing protein 27 GO:0044424 GO:0019904//protein domain specific binding - "gi|1407663|gb|AAC52641.1|/4.50255e-121/SH3P2, partial [Mus musculus]" 20740 8006.46 52.3 45.21333333 -0.210062663 Down 0.43202076 Sptan1 "spectrin alpha, non-erythrocytic 1" K06114|1|0.0|4717|mmu:20740|spectrin alpha - - - "gi|568913202|ref|XP_006497872.1|/0/PREDICTED: spectrin alpha chain, non-erythrocytic 1 isoform X1 [Mus musculus]" 72536 3076 1.256666667 2.013333333 0.679984026 Up 0.432001956 Tagap T cell activation Rho GTPase activating protein K01468|1|2e-35|154|clv:102098075|imidazolonepropionase [EC:3.5.2.7];K08007|2|1e-18|98.6|fch:102047215|villin 2 (ezrin);K18470|3|2e-18|97.4|hgl:101721725|Rho GTPase-activating protein 1 GO:0044464 GO:0030695//GTPase regulator activity GO:0007154//cell communication gi|22165374|ref|NP_666080.1|/0/T-cell activation Rho GTPase-activating protein [Mus musculus] 76594 5169 6.28 7.813333333 0.315173605 Up 0.431945541 Dnajc18 DnaJ heat shock protein family (Hsp40) member C18 K09538|1|0.0|663|mmu:76594|DnaJ homolog subfamily C member 18 - - - - 234069 2408 5.233333333 6.633333333 0.342003872 Up 0.431691677 Pcid2 PCI domain containing 2 - - - "GO:0006351//transcription, DNA-templated;GO:0010951//negative regulation of endopeptidase activity;GO:0030183//B cell differentiation;GO:0006915//apoptotic process;GO:0043487//regulation of RNA stability;GO:0090232//positive regulation of spindle checkpoint" gi|918577090|ref|XP_005374010.2|/0/PREDICTED: PCI domain-containing protein 2 [Chinchilla lanigera] 13876 3166.79 10.97666667 9.013333333 -0.28430736 Down 0.431381398 Erg avian erythroblastosis virus E-26 (v-ets) oncogene related K09435|1|0.0|930|mmu:13876|transcriptional regulator ERG GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006464//cellular protein modification process;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0032502//developmental process;GO:0006464//cellular protein modification process;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0032502//developmental process;GO:0006464//cellular protein modification process;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0032502//developmental process;GO:0006464//cellular protein modification process;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0032502//developmental process;GO:0006464//cellular protein modification process;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0032502//developmental process;GO:0006464//cellular protein modification process;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0032502//developmental process" gi|694016503|ref|NP_001289112.1|/0/transcriptional regulator ERG isoform 6 [Mus musculus] 52250 3815 4.956666667 6.296666667 0.345218054 Up 0.431202753 Reep1 receptor accessory protein 1 K17338|1|3e-82|310|hgl:101724993|receptor expression-enhancing protein 1/2/3/4 - - - - 67896 3648 32.46666667 27.82333333 -0.222664001 Down 0.431174546 Ccdc80 coiled-coil domain containing 80 K19408|1|3e-10|70.9|umr:103672995|sushi repeat-containing protein SRPX2 GO:0005578//proteinaceous extracellular matrix GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding GO:0043062//extracellular structure organization;GO:0010810//regulation of cell-substrate adhesion gi|110625752|ref|NP_080715.2|/0/coiled-coil domain-containing protein 80 precursor [Mus musculus] 20302 804 0.13 0.58 2.157541277 Up 0.431118132 Ccl3 chemokine (C-C motif) ligand 3 K05408|1|1e-47|191|mmu:20302|C-C motif chemokine 3 GO:0044444//cytoplasmic part;GO:0044421 GO:0004697//protein kinase C activity;GO:0005539//glycosaminoglycan binding;GO:0048020//CCR chemokine receptor binding;GO:0005125//cytokine activity;GO:0060229//lipase activator activity GO:0043065//positive regulation of apoptotic process;GO:0006954//inflammatory response;GO:0070555//response to interleukin-1;GO:0044093;GO:0006996//organelle organization;GO:0006796//phosphate-containing compound metabolic process;GO:0034341//response to interferon-gamma;GO:0008347//glial cell migration;GO:0019233//sensory perception of pain;GO:0043410//positive regulation of MAPK cascade;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0036314;GO:0007166//cell surface receptor signaling pathway;GO:0002278;GO:0032731//positive regulation of interleukin-1 beta production;GO:0006366//transcription from RNA polymerase II promoter;GO:0006464//cellular protein modification process;GO:0019722//calcium-mediated signaling;GO:0022604//regulation of cell morphogenesis;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0016192//vesicle-mediated transport;GO:0051209//release of sequestered calcium ion into cytosol;GO:0034612//response to tumor necrosis factor;GO:0030279//negative regulation of ossification;GO:0032897//negative regulation of viral transcription "gi|563404456|emb|CDI30253.1|/2.89342e-61/C-C motif chemokine 3, partial [Mus musculus]" 235320 5114 50.79333333 43.97 -0.208119622 Down 0.431080522 Zbtb16 zinc finger and BTB domain containing 16 K10055|1|0.0|1350|mmu:235320|zinc finger and BTB domain-containing protein 16 GO:0016020//membrane;GO:0016604//nuclear body;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0043566//structure-specific DNA binding GO:0051094//positive regulation of developmental process;GO:0002062//chondrocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001822//kidney development;GO:0007283//spermatogenesis;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0001503//ossification;GO:0030326//embryonic limb morphogenesis;GO:0045444//fat cell differentiation;GO:0003002//regionalization;GO:0030099//myeloid cell differentiation;GO:0032446//protein modification by small protein conjugation;GO:0007399//nervous system development;GO:0033365//protein localization to organelle gi|84794629|ref|NP_001028496.1|/0/zinc finger and BTB domain-containing protein 16 [Mus musculus] 76612 2266.68 2.883333333 1.993333333 -0.532554648 Down 0.431061717 Lrrc27 leucine rich repeat containing 27 K14837|1|3e-16|90.1|nve:NEMVE_v1g244547|nucleolar protein 12;K10641|2|4e-09|66.2|mcf:102122209|E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27] - - - gi|219555695|ref|NP_001137227.1|/0/leucine-rich repeat-containing protein 27 isoform b [Mus musculus] 54673 3752.1 108.2533333 93.99333333 -0.20378111 Down 0.430732634 Sh3glb1 SH3-domain GRB2-like B1 (endophilin) K11248|1|0.0|675|mmu:54673|endophilin-B GO:0032991//macromolecular complex;GO:0031966//mitochondrial membrane;GO:0012505//endomembrane system;GO:0032991//macromolecular complex;GO:0031966//mitochondrial membrane;GO:0012505//endomembrane system;GO:0032991//macromolecular complex;GO:0031966//mitochondrial membrane;GO:0012505//endomembrane system "GO:0016411//acylglycerol O-acyltransferase activity;GO:0030674//protein binding, bridging;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0008289//lipid binding;GO:0016411//acylglycerol O-acyltransferase activity;GO:0030674//protein binding, bridging;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0008289//lipid binding;GO:0016411//acylglycerol O-acyltransferase activity;GO:0030674//protein binding, bridging;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0008289//lipid binding" GO:0006458//'de novo' protein folding;GO:0006915//apoptotic process;GO:0010822//positive regulation of mitochondrion organization;GO:0007154//cell communication;GO:0031334//positive regulation of protein complex assembly;GO:0030031//cell projection assembly;GO:0012502//induction of programmed cell death;GO:0046473//phosphatidic acid metabolic process;GO:0006458//'de novo' protein folding;GO:0006915//apoptotic process;GO:0010822//positive regulation of mitochondrion organization;GO:0007154//cell communication;GO:0031334//positive regulation of protein complex assembly;GO:0030031//cell projection assembly;GO:0012502//induction of programmed cell death;GO:0046473//phosphatidic acid metabolic process;GO:0006458//'de novo' protein folding;GO:0006915//apoptotic process;GO:0010822//positive regulation of mitochondrion organization;GO:0007154//cell communication;GO:0031334//positive regulation of protein complex assembly;GO:0030031//cell projection assembly;GO:0012502//induction of programmed cell death;GO:0046473//phosphatidic acid metabolic process gi|50510503|dbj|BAD32237.1|/0/mKIAA0491 protein [Mus musculus] 106025 1747 20.70666667 24.36666667 0.234813576 Up 0.430648012 Sharpin SHANK-associated RH domain interacting protein K10630|1|3e-40|169|acs:100564158|RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.27] GO:0044327//dendritic spine head;GO:0000151//ubiquitin ligase complex;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0043130//ubiquitin binding GO:0000209//protein polyubiquitination;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0007417//central nervous system development;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0006996//organelle organization;GO:0051259//protein oligomerization;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006954//inflammatory response;GO:0030216//keratinocyte differentiation "gi|148697607|gb|EDL29554.1|/9.49942e-167/SHANK-associated RH domain interacting protein, isoform CRA_b, partial [Mus musculus]" 216635 604 0.01 0.323333333 5.014950341 Up 0.430591598 Hbq1a "hemoglobin, theta 1A" K13827|1|2e-51|204|mmu:544763|hemoglobin subunit theta - GO:0046872//metal ion binding;GO:0022892//substrate-specific transporter activity GO:0015669 "gi|33239411|ref|NP_778165.1|/3.00158e-67/hemoglobin, theta T2 [Mus musculus]" 106740 1088 4.29 5.526666667 0.365431953 Up 0.430431757 LOC106740 uncharacterized LOC106740 - - - - - 75991 4849.13 32.06666667 27.50333333 -0.221467913 Down 0.430431757 Slain2 "SLAIN motif family, member 2" K16580|1|0.0|722|rno:305310|SLAIN motif-containing protein 1/2 GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton - GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0031110//regulation of microtubule polymerization or depolymerization gi|37360394|dbj|BAC98175.1|/0/mKIAA1458 protein [Mus musculus] 66460 1623 13.80333333 16.40666667 0.249265455 Up 0.430422355 Sys1 SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae) K20318|1|2e-85|318|cge:100764663|protein SYS1 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0045184//establishment of protein localization gi|672017709|ref|XP_008773833.1|/5.17651e-95/PREDICTED: protein SYS1 homolog isoform X1 [Rattus norvegicus] 17110 1282 3.216666667 4.3 0.418770218 Up 0.430328331 Lyz1 lysozyme 1 K13915|1|7e-78|293|mmu:17110|lysozyme C [EC:3.2.1.17] - - - - 11754 4396 12.04666667 9.956666667 -0.274899269 Down 0.430300124 Aoc3 "amine oxidase, copper containing 3" K00276|1|0.0|1481|mmu:11754|primary-amine oxidase [EC:1.4.3.21] GO:0031224//intrinsic component of membrane;GO:0043227//membrane-bounded organelle;GO:0044464;GO:0044421 "GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0005216//ion channel activity;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0048037//cofactor binding" GO:0009636//response to toxic substance;GO:0022610;GO:0044710;GO:0002526//acute inflammatory response;GO:1901564;GO:0044767//single-organism developmental process;GO:0002684//positive regulation of immune system process;GO:0010827//regulation of glucose transport;GO:0008015//blood circulation;GO:0007631//feeding behavior gi|6753066|ref|NP_033805.1|/0/membrane primary amine oxidase [Mus musculus] 233571 1917 4.02 5.216666667 0.37593275 Up 0.430262515 P2ry6 "pyrimidinergic receptor P2Y, G-protein coupled, 6" "K04272|1|1e-180|635|mmu:233571|purinergic receptor P2Y, G protein-coupled, 6" GO:0031224//intrinsic component of membrane;GO:0044459 GO:0015065//uridine nucleotide receptor activity;GO:0000166//nucleotide binding GO:0006821//chloride transport;GO:0014909//smooth muscle cell migration;GO:0035588 gi|34147203|ref|NP_898991.1|/1.09948e-179/P2Y purinoceptor 6 [Mus musculus] 22344 4597 20.00666667 16.99666667 -0.235228981 Down 0.429980443 Vezf1 vascular endothelial zinc finger 1 K17559|1|1e-157|560|chx:102182741|phostensin;K03252|2|1e-31|142|aam:106489419|translation initiation factor 3 subunit C;K09228|4|9e-30|135|obi:106878000|KRAB domain-containing zinc finger protein - - - gi|4106547|gb|AAD02883.1|/0/vascular endothelial zinc finger 1 [Mus musculus] 381339 1096 87.69666667 100.8366667 0.201426421 Up 0.429933431 Tmem182 transmembrane protein 182 "K14722|1|3e-21|105|tgu:100222639|solute carrier family 9 (sodium/hydrogen exchanger), member 2" GO:0031224//intrinsic component of membrane - - gi|124487103|ref|NP_001074667.1|/2.23695e-111/transmembrane protein 182 precursor [Mus musculus] 15191 2257 87.47666667 100.5633333 0.201134224 Up 0.429905224 Hdgf hepatoma-derived growth factor K16641|1|1e-113|413|mmu:15191|hepatoma-derived growth factor GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044421 GO:0003676//nucleic acid binding;GO:0001221//transcription cofactor binding;GO:0005102//receptor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005539//glycosaminoglycan binding;GO:0036094//small molecule binding GO:0033365//protein localization to organelle;GO:0006366//transcription from RNA polymerase II promoter gi|12857334|dbj|BAB30979.1|/8.34268e-113/unnamed protein product [Mus musculus] 103733 1609 27.09 31.58333333 0.221403049 Up 0.429895822 Tubg1 "tubulin, gamma 1" K10389|1|0.0|874|cge:100759432|tubulin gamma GO:0005874//microtubule;GO:0005813//centrosome;GO:0000228//nuclear chromosome;GO:0044444//cytoplasmic part;GO:0000922//spindle pole GO:0005198//structural molecule activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0007051//spindle organization;GO:0044772//mitotic cell cycle phase transition;GO:0007067//mitotic nuclear division;GO:0043623//cellular protein complex assembly;GO:0009154//purine ribonucleotide catabolic process "gi|148671944|gb|EDL03891.1|/0/mCG20203, isoform CRA_b, partial [Mus musculus]" 14000 4580 24.85333333 21.24333333 -0.226429199 Down 0.429830005 Drosha "drosha, ribonuclease type III" K03685|1|0.0|2106|mmu:14000|ribonuclease III [EC:3.1.26.3] - GO:0005488//binding;GO:0004521//endoribonuclease activity;GO:0005488//binding;GO:0004521//endoribonuclease activity GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0034660//ncRNA metabolic process;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0034660//ncRNA metabolic process gi|194306545|ref|NP_081075.3|/0/ribonuclease 3 [Mus musculus] 243842 5360 9.78 7.99 -0.291638962 Down 0.429735981 Gltscr1 glioma tumor suppressor candidate region gene 1 K14971|1|2e-08|65.5|phu:Phum_PHUM494000|nuclear receptor coactivator 6;K18740|2|5e-07|60.5|hro:HELRODRAFT_178574|exonuclease 3'-5' domain-containing protein 1;K20412|3|4e-06|44.3|cjo:107324677|peptidase inhibitor 16 - GO:0005488//binding - gi|124487237|ref|NP_001074887.1|/0/glioma tumor suppressor candidate region gene 1 protein [Mus musculus] 235184 2307 1.79 2.64 0.560578342 Up 0.429735981 Msantd2 Myb/SANT-like DNA-binding domain containing 2 K17757|1|3e-07|60.1|cjo:107307941|ATP-dependent NAD(P)H-hydrate dehydratase [EC:4.2.1.93] - - - gi|568959297|ref|XP_006510294.1|/0/PREDICTED: myb/SANT-like DNA-binding domain-containing protein 2 isoform X2 [Mus musculus] 66821 1852.2 20.65333333 24.25666667 0.232006667 Up 0.42965136 Bcs1l BCS1-like (yeast) K08900|1|0.0|793|mmu:66821|mitochondrial chaperone BCS1 GO:0031224//intrinsic component of membrane;GO:0005746//mitochondrial respiratory chain;GO:0031224//intrinsic component of membrane;GO:0005746//mitochondrial respiratory chain GO:0032550;GO:0016462//pyrophosphatase activity;GO:0032550;GO:0016462//pyrophosphatase activity GO:0006996//organelle organization;GO:0010257//NADH dehydrogenase complex assembly;GO:0017062//respiratory chain complex III assembly;GO:0008535//respiratory chain complex IV assembly;GO:0006996//organelle organization;GO:0010257//NADH dehydrogenase complex assembly;GO:0017062//respiratory chain complex III assembly;GO:0008535//respiratory chain complex IV assembly gi|21313544|ref|NP_080060.1|/0/mitochondrial chaperone BCS1 [Mus musculus] 67706 848 8.84 10.76 0.283559803 Up 0.429585543 Tmem179b transmembrane protein 179B K03131|1|1e-53|211|bacu:102998317|transcription initiation factor TFIID subunit 6 GO:0016020//membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|257467568|ref|NP_080601.2|/1.97193e-84/transmembrane protein 179B precursor [Mus musculus] 105014 1475 20.65 24.24 0.231247917 Up 0.429463312 Rdh14 retinol dehydrogenase 14 (all-trans and 9-cis) K11162|1|4e-166|587|mmu:105014|retinol dehydrogenase 14 [EC:1.1.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0036094//small molecule binding;GO:0003824//catalytic activity GO:0044710 gi|12963791|ref|NP_076186.1|/3.18992e-165/retinol dehydrogenase 14 [Mus musculus] 114584 1159 40.20666667 46.6 0.21289522 Up 0.429406898 Clic1 chloride intracellular channel 1 K05021|1|2e-136|488|mmu:114584|chloride intracellular channel protein 1 GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0005635//nuclear envelope;GO:0034702//ion channel complex GO:0005488//binding;GO:0005254//chloride channel activity GO:0015698//inorganic anion transport;GO:0001649//osteoblast differentiation;GO:0042391//regulation of membrane potential;GO:0007154//cell communication;GO:0034220//ion transmembrane transport gi|426352465|ref|XP_004043733.1|/6.82093e-138/PREDICTED: chloride intracellular channel protein 1 isoform 2 [Gorilla gorilla gorilla] 100317 4347.52 19.24666667 16.26666667 -0.24268996 Down 0.429303471 AU040320 expressed sequence AU040320 K15619|1|2e-09|67.8|mgp:100540482|Kunitz-type protease inhibitor 1 GO:0031224//intrinsic component of membrane;GO:0031410//cytoplasmic vesicle;GO:0031224//intrinsic component of membrane;GO:0031410//cytoplasmic vesicle;GO:0031224//intrinsic component of membrane;GO:0031410//cytoplasmic vesicle - - "gi|148698327|gb|EDL30274.1|/0/expressed sequence AU040320, isoform CRA_b, partial [Mus musculus]" 30838 1946 13.77333333 16.32666667 0.24535252 Up 0.429284667 Fbxw4 F-box and WD-40 domain protein 4 K10262|1|0.0|776|mmu:30838|F-box and WD-40 domain protein 4 - - GO:0007166//cell surface receptor signaling pathway;GO:0001501//skeletal system development;GO:0030326//embryonic limb morphogenesis gi|532017340|ref|XP_005352423.1|/0/PREDICTED: F-box/WD repeat-containing protein 4 [Microtus ochrogaster] 380765 689 3.053333333 4.103333333 0.426411258 Up 0.42921885 D830013O20Rik RIKEN cDNA D830013O20 gene - - - - gi|26351809|dbj|BAC39541.1|/2.07037e-58/unnamed protein product [Mus musculus] 21402 1454 81.21 93.54333333 0.203977451 Up 0.429209448 Skp1a S-phase kinase-associated protein 1A K03094|1|7e-69|263|xma:102221489|S-phase kinase-associated protein 1 - - - - 219094 3876 5.19 4 -0.375734539 Down 0.429106021 Khnyn KH and NYN domain containing K18668|1|9e-46|188|cin:100183892|ribonuclease ZC3H12 [EC:3.1.-.-] - - - gi|28972151|dbj|BAC65529.1|/0/mKIAA0323 protein [Mus musculus] 100609 2242 4.776666667 6.09 0.350438024 Up 0.428852157 Nsun5 "NOL1/NOP2/Sun domain family, member 5" K15264|1|0.0|829|mmu:100609|putative methyltransferase [EC:2.1.1.-] - GO:0016741 GO:0008152//metabolic process gi|154146245|ref|NP_663389.2|/0/probable 28S rRNA (cytosine-C(5))-methyltransferase [Mus musculus] 50768 6215.45 23.95 20.41333333 -0.230513874 Down 0.428776938 Dlc1 deleted in liver cancer 1 K10360|1|9e-19|99.8|aec:105148452|myosin IX;K05732|2|1e-18|99.4|tru:101068709|glucocorticoid receptor DNA-binding factor 1 - - - - 59042 1043 80.06666667 92.01 0.200588922 Up 0.428758133 Cope "coatomer protein complex, subunit epsilon" K17268|1|1e-154|548|mmu:59042|coatomer subunit epsilon GO:0030137//COPI-coated vesicle;GO:0030120//vesicle coat - GO:0048193//Golgi vesicle transport;GO:0045184//establishment of protein localization gi|10946972|ref|NP_067513.1|/9.78872e-154/coatomer subunit epsilon [Mus musculus] 66591 1288 10.16 12.21333333 0.265556601 Up 0.428729926 Mad2l1bp MAD2L1 binding protein - - - - - 81500 1715 10.08333333 12.13333333 0.267003308 Up 0.428729926 Sil1 endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae) K14001|1|0.0|822|mmu:81500|nucleotide exchange factor SIL1 GO:0044432 - GO:0045184//establishment of protein localization gi|257196264|ref|NP_109674.2|/0/nucleotide exchange factor SIL1 precursor [Mus musculus] 14254 6280 8.81 10.71 0.281744556 Up 0.428654707 Flt1 FMS-like tyrosine kinase 1 K05096|1|0.0|2566|mmu:14254|FMS-like tyrosine kinase 1 [EC:2.7.10.1] GO:0031981//nuclear lumen;GO:0016021//integral component of membrane GO:0032550;GO:0005515//protein binding;GO:0005021//vascular endothelial growth factor-activated receptor activity GO:0043405//regulation of MAP kinase activity;GO:0008284//positive regulation of cell proliferation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0010518//positive regulation of phospholipase activity;GO:0006937//regulation of muscle contraction;GO:0009967//positive regulation of signal transduction;GO:0048869//cellular developmental process;GO:0030595//leukocyte chemotaxis;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0001525//angiogenesis;GO:0071363//cellular response to growth factor stimulus;GO:0006950//response to stress gi|34328180|ref|NP_034358.2|/0/vascular endothelial growth factor receptor 1 precursor [Mus musculus] 330657 2531 2.283333333 3.21 0.49143181 Up 0.428513671 Prss53 "protease, serine 53" K09630|1|5e-87|325|xtr:101733979|polyserase 2 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|60359900|dbj|BAD90169.1|/0/mFLJ00289 protein [Mus musculus] 320609 5370 15.72666667 13.21 -0.251582451 Down 0.42839144 Strip2 striatin interacting protein 2 K19603|1|2e-10|71.6|smm:Smp_133500|mitogen-activated protein kinase 15 [EC:2.7.11.24] - - - - 21385 3562 6.45 5.086666667 -0.342578604 Down 0.428372635 Tbx2 T-box 2 K10176|1|0.0|1068|mmu:21385|T-box protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0003151//outflow tract morphogenesis;GO:0051093//negative regulation of developmental process;GO:0006366//transcription from RNA polymerase II promoter;GO:0060592//mammary gland formation;GO:0007569//cell aging;GO:0030326//embryonic limb morphogenesis;GO:0035904//aorta development;GO:0008284//positive regulation of cell proliferation;GO:0060379//cardiac muscle cell myoblast differentiation;GO:0001709//cell fate determination;GO:0031076//embryonic camera-type eye development;GO:0048565//digestive tract development gi|120407039|ref|NP_033350.2|/0/T-box transcription factor TBX2 [Mus musculus] 66282 1088 7.013333333 5.59 -0.327252016 Down 0.428250404 Tma16 translation machinery associated 16 K14860|1|2e-124|447|mmu:66282|translation machinery-associated protein 16 - - - gi|13384880|ref|NP_079741.1|/1.48e-123/translation machinery-associated protein 16 [Mus musculus] 11539 5012.8 8.156666667 6.59 -0.30770123 Down 0.428128173 Adora1 adenosine A1 receptor K04265|1|3e-140|503|mmu:11539|adenosine A1 receptor GO:0031224//intrinsic component of membrane;GO:0033267;GO:0032589//neuron projection membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044327//dendritic spine head;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0031224//intrinsic component of membrane;GO:0033267;GO:0032589//neuron projection membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044327//dendritic spine head;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0031224//intrinsic component of membrane;GO:0033267;GO:0032589//neuron projection membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044327//dendritic spine head;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0031224//intrinsic component of membrane;GO:0033267;GO:0032589//neuron projection membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044327//dendritic spine head;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0031224//intrinsic component of membrane;GO:0033267;GO:0032589//neuron projection membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044327//dendritic spine head;GO:0044297//cell body;GO:0097060//synaptic membrane GO:0001882//nucleoside binding;GO:0004620//phospholipase activity;GO:0005102//receptor binding;GO:0004930//G-protein coupled receptor activity;GO:0032403//protein complex binding;GO:0046983//protein dimerization activity;GO:0001882//nucleoside binding;GO:0004620//phospholipase activity;GO:0005102//receptor binding;GO:0004930//G-protein coupled receptor activity;GO:0032403//protein complex binding;GO:0046983//protein dimerization activity;GO:0001882//nucleoside binding;GO:0004620//phospholipase activity;GO:0005102//receptor binding;GO:0004930//G-protein coupled receptor activity;GO:0032403//protein complex binding;GO:0046983//protein dimerization activity;GO:0001882//nucleoside binding;GO:0004620//phospholipase activity;GO:0005102//receptor binding;GO:0004930//G-protein coupled receptor activity;GO:0032403//protein complex binding;GO:0046983//protein dimerization activity;GO:0001882//nucleoside binding;GO:0004620//phospholipase activity;GO:0005102//receptor binding;GO:0004930//G-protein coupled receptor activity;GO:0032403//protein complex binding;GO:0046983//protein dimerization activity "GO:0048871//multicellular organismal homeostasis;GO:0002790//peptide secretion;GO:0032898;GO:0006470//protein dephosphorylation;GO:0035588;GO:0042321//negative regulation of circadian sleep/wake cycle, sleep;GO:0051899//membrane depolarization;GO:0008016//regulation of heart contraction;GO:0042311//vasodilation;GO:0019233//sensory perception of pain;GO:0035249//synaptic transmission, glutamatergic;GO:0006629//lipid metabolic process;GO:0009895;GO:0035813//regulation of renal sodium excretion;GO:0014047//glutamate secretion;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0002526//acute inflammatory response;GO:0006605//protein targeting;GO:0001977;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0046879//hormone secretion;GO:0002683//negative regulation of immune system process;GO:0045988//negative regulation of striated muscle contraction;GO:0006813//potassium ion transport;GO:0008283//cell proliferation;GO:0051048//negative regulation of secretion;GO:0015858//nucleoside transport;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0048871//multicellular organismal homeostasis;GO:0002790//peptide secretion;GO:0032898;GO:0006470//protein dephosphorylation;GO:0035588;GO:0042321//negative regulation of circadian sleep/wake cycle, sleep;GO:0051899//membrane depolarization;GO:0008016//regulation of heart contraction;GO:0042311//vasodilation;GO:0019233//sensory perception of pain;GO:0035249//synaptic transmission, glutamatergic;GO:0006629//lipid metabolic process;GO:0009895;GO:0035813//regulation of renal sodium excretion;GO:0014047//glutamate secretion;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0002526//acute inflammatory response;GO:0006605//protein targeting;GO:0001977;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0046879//hormone secretion;GO:0002683//negative regulation of immune system process;GO:0045988//negative regulation of striated muscle contraction;GO:0006813//potassium ion transport;GO:0008283//cell proliferation;GO:0051048//negative regulation of secretion;GO:0015858//nucleoside transport;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0048871//multicellular organismal homeostasis;GO:0002790//peptide secretion;GO:0032898;GO:0006470//protein dephosphorylation;GO:0035588;GO:0042321//negative regulation of circadian sleep/wake cycle, sleep;GO:0051899//membrane depolarization;GO:0008016//regulation of heart contraction;GO:0042311//vasodilation;GO:0019233//sensory perception of pain;GO:0035249//synaptic transmission, glutamatergic;GO:0006629//lipid metabolic process;GO:0009895;GO:0035813//regulation of renal sodium excretion;GO:0014047//glutamate secretion;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0002526//acute inflammatory response;GO:0006605//protein targeting;GO:0001977;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0046879//hormone secretion;GO:0002683//negative regulation of immune system process;GO:0045988//negative regulation of striated muscle contraction;GO:0006813//potassium ion transport;GO:0008283//cell proliferation;GO:0051048//negative regulation of secretion;GO:0015858//nucleoside transport;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0048871//multicellular organismal homeostasis;GO:0002790//peptide secretion;GO:0032898;GO:0006470//protein dephosphorylation;GO:0035588;GO:0042321//negative regulation of circadian sleep/wake cycle, sleep;GO:0051899//membrane depolarization;GO:0008016//regulation of heart contraction;GO:0042311//vasodilation;GO:0019233//sensory perception of pain;GO:0035249//synaptic transmission, glutamatergic;GO:0006629//lipid metabolic process;GO:0009895;GO:0035813//regulation of renal sodium excretion;GO:0014047//glutamate secretion;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0002526//acute inflammatory response;GO:0006605//protein targeting;GO:0001977;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0046879//hormone secretion;GO:0002683//negative regulation of immune system process;GO:0045988//negative regulation of striated muscle contraction;GO:0006813//potassium ion transport;GO:0008283//cell proliferation;GO:0051048//negative regulation of secretion;GO:0015858//nucleoside transport;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0048871//multicellular organismal homeostasis;GO:0002790//peptide secretion;GO:0032898;GO:0006470//protein dephosphorylation;GO:0035588;GO:0042321//negative regulation of circadian sleep/wake cycle, sleep;GO:0051899//membrane depolarization;GO:0008016//regulation of heart contraction;GO:0042311//vasodilation;GO:0019233//sensory perception of pain;GO:0035249//synaptic transmission, glutamatergic;GO:0006629//lipid metabolic process;GO:0009895;GO:0035813//regulation of renal sodium excretion;GO:0014047//glutamate secretion;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0002526//acute inflammatory response;GO:0006605//protein targeting;GO:0001977;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0046879//hormone secretion;GO:0002683//negative regulation of immune system process;GO:0045988//negative regulation of striated muscle contraction;GO:0006813//potassium ion transport;GO:0008283//cell proliferation;GO:0051048//negative regulation of secretion;GO:0015858//nucleoside transport;GO:0032228//regulation of synaptic transmission, GABAergic" gi|633257726|ref|NP_001278857.1|/6.46205e-97/adenosine receptor A1 isoform b [Mus musculus] 58226 8240 1.563333333 0.893333333 -0.807354922 Down 0.428043552 Cacna1h "calcium channel, voltage-dependent, T type, alpha 1H subunit" K04855|1|0.0|3385|mmu:58226|voltage-dependent calcium channel T type alpha-1H - - - gi|254826788|ref|NP_001157163.1|/0/voltage-dependent T-type calcium channel subunit alpha-1H isoform 2 [Mus musculus] 26992 2370 44.03666667 37.94 -0.21498559 Down 0.428043552 Brd7 bromodomain containing 7 K11723|1|0.0|1214|mmu:26992|bromodomain-containing protein 7/9 GO:0043231//intracellular membrane-bounded organelle GO:0042393//histone binding;GO:0003712//transcription cofactor activity;GO:0000975//regulatory region DNA binding GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0016573//histone acetylation gi|6755234|ref|NP_036177.1|/0/bromodomain-containing protein 7 [Mus musculus] 100039707 783 5.083333333 3.903333333 -0.381068167 Down 0.428015345 Mthfsl "5, 10-methenyltetrahydrofolate synthetase-like" K01934|1|5e-105|382|mmu:100039707|5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0032550;GO:0016882//cyclo-ligase activity GO:0006915//apoptotic process;GO:0006760//folic acid-containing compound metabolic process "gi|190610049|ref|NP_001122073.1|/4.26457e-104/5, 10-methenyltetrahydrofolate synthetase-like [Mus musculus]" 217340 4655 1.626666667 2.433333333 0.581015316 Up 0.428015345 Rnf157 ring finger protein 157 K10604|1|2e-155|553|lcm:102358123|E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27] - - - gi|255003680|ref|NP_081534.1|/0/RING finger protein 157 [Mus musculus] 18054 1176 0.3 0.806666667 1.427010141 Up 0.427977735 Ngp neutrophilic granule protein K13916|1|1e-13|80.1|mcf:102139204|cathelicidin antimicrobial peptide - - - - 15186 2415 1.703333333 2.536666667 0.574573163 Up 0.427940126 Hdc histidine decarboxylase K01590|1|0.0|1314|mmu:15186|histidine decarboxylase [EC:4.1.1.22] GO:0043005//neuron projection;GO:0044297//cell body;GO:0044444//cytoplasmic part GO:0042802//identical protein binding;GO:0031406//carboxylic acid binding;GO:0016831//carboxy-lyase activity GO:0001692//histamine metabolic process;GO:0006547//histidine metabolic process;GO:0006584//catecholamine metabolic process gi|28173556|ref|NP_032256.3|/0/histidine decarboxylase [Mus musculus] 233065 963 13.24333333 15.74 0.249169248 Up 0.427864907 Alkbh6 alkB homolog 6 K10768|1|2e-136|487|mmu:233065|alkylated DNA repair protein alkB homolog 6 [EC:1.14.11.-] - - - - 20384 1568.37 76.15333333 87.36 0.198065669 Up 0.427827297 Srsf5 serine/arginine-rich splicing factor 5 "K12893|1|2e-74|282|pale:102890422|splicing factor, arginine/serine-rich 4/5/6" GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding GO:0007049//cell cycle;GO:0000245//spliceosomal complex assembly;GO:0006405//RNA export from nucleus;GO:0006366//transcription from RNA polymerase II promoter;GO:0007049//cell cycle;GO:0000245//spliceosomal complex assembly;GO:0006405//RNA export from nucleus;GO:0006366//transcription from RNA polymerase II promoter;GO:0007049//cell cycle;GO:0000245//spliceosomal complex assembly;GO:0006405//RNA export from nucleus;GO:0006366//transcription from RNA polymerase II promoter gi|987939967|ref|XP_015417521.1|/1.354e-73/PREDICTED: serine/arginine-rich splicing factor 5 isoform X2 [Myotis davidii] 269855 4260 4.493333333 3.39 -0.406500817 Down 0.427780285 Ssc5d "scavenger receptor cysteine rich family, 5 domains" K13912|1|2e-129|466|aam:106482036|deleted in malignant brain tumors 1 protein GO:0044424 - GO:0032502//developmental process;GO:0006952//defense response;GO:0032677 gi|27370514|ref|NP_766596.1|/0/soluble scavenger receptor cysteine-rich domain-containing protein SSC5D precursor [Mus musculus] 72662 3722 3.09 2.183333333 -0.501074432 Down 0.427667456 Dis3 "DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease" K12585|1|0.0|1803|mmu:72662|exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] - - - - 69094 840 38.26333333 44.24 0.209388825 Up 0.427441799 Tmem160 transmembrane protein 160 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|58037143|ref|NP_081214.1|/2.20851e-80/transmembrane protein 160 [Mus musculus] 76025 2963.4 9.753333333 11.77333333 0.271555574 Up 0.427432397 Cant1 calcium activated nucleotidase 1 K12304|1|0.0|836|mmu:76025|soluble calcium-activated nucleotidase 1 [EC:3.6.1.6] GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane GO:0046872//metal ion binding;GO:0060089;GO:0017110//nucleoside-diphosphatase activity;GO:0046872//metal ion binding;GO:0060089;GO:0017110//nucleoside-diphosphatase activity;GO:0046872//metal ion binding;GO:0060089;GO:0017110//nucleoside-diphosphatase activity;GO:0046872//metal ion binding;GO:0060089;GO:0017110//nucleoside-diphosphatase activity;GO:0046872//metal ion binding;GO:0060089;GO:0017110//nucleoside-diphosphatase activity GO:0006029//proteoglycan metabolic process;GO:0009134//nucleoside diphosphate catabolic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006029//proteoglycan metabolic process;GO:0009134//nucleoside diphosphate catabolic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006029//proteoglycan metabolic process;GO:0009134//nucleoside diphosphate catabolic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006029//proteoglycan metabolic process;GO:0009134//nucleoside diphosphate catabolic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006029//proteoglycan metabolic process;GO:0009134//nucleoside diphosphate catabolic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling "gi|148702719|gb|EDL34666.1|/0/calcium activated nucleotidase 1, isoform CRA_c, partial [Mus musculus]" 320091 4177 1.353333333 0.72 -0.910448415 Down 0.427394787 Ano4 anoctamin 4 K19499|1|0.0|1957|mcf:102114977|anoctamin-4 - - - "gi|148689550|gb|EDL21497.1|/0/transmembrane protein 16D (eight membrane-spanning domains), isoform CRA_a, partial [Mus musculus]" 109212 1466 0.71 1.336666667 0.912748806 Up 0.427394787 Fam64a "family with sequence similarity 64, member A" - GO:0031981//nuclear lumen - - gi|27735010|ref|NP_653109.2|/3.01514e-99/protein FAM64A [Mus musculus] 14366 3685 5.35 4.136666667 -0.371070182 Down 0.427357178 Fzd4 frizzled class receptor 4 K02354|1|0.0|1041|mmu:14366|frizzled 4 - - - - 66087 1958 37.62 43.55666667 0.211393702 Up 0.427253752 Emc3 ER membrane protein complex subunit 3 K02907|1|2e-08|63.9|dgr:Dgri_GH17886|large subunit ribosomal protein L30 GO:0030176//integral component of endoplasmic reticulum membrane - - "gi|148667067|gb|EDK99483.1|/4.613e-165/mCG132973, isoform CRA_a, partial [Mus musculus]" 59006 1153 1167.076667 1023.083333 -0.189975675 Down 0.427075106 Myoz2 myozenin 2 - GO:0005856//cytoskeleton;GO:0031674//I band GO:0008092//cytoskeletal protein binding - gi|10946916|ref|NP_067478.1|/6.11829e-139/myozenin-2 [Mus musculus] 13808 1517.78 1098.613333 961.6266667 -0.192134898 Down 0.427018692 Eno3 "enolase 3, beta muscle" K01689|1|0.0|840|myb:102240806|enolase [EC:4.2.1.11] GO:0044424;GO:0044424;GO:0044424 GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0016836//hydro-lyase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0016836//hydro-lyase activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0016836//hydro-lyase activity GO:0042221//response to chemical;GO:0006007//glucose catabolic process;GO:0042246//tissue regeneration;GO:0042221//response to chemical;GO:0006007//glucose catabolic process;GO:0042246//tissue regeneration;GO:0006007//glucose catabolic process gi|625267230|ref|XP_007625118.1|/0/PREDICTED: beta-enolase isoform X2 [Cricetulus griseus] 20491 3135 0.763333333 1.4 0.87504173 Up 0.42697168 Sla src-like adaptor K08893|1|5e-33|145|xma:102216930|hemopoietic cell kinase [EC:2.7.10.2];K08890|2|2e-32|143|cmy:102931113|B lymphoid tyrosine kinase [EC:2.7.10.2] GO:0043231//intracellular membrane-bounded organelle - - gi|71067091|ref|NP_001025012.1|/1.13207e-149/src-like-adapter isoform a [Mus musculus] 16476 3187 29.42333333 25.23 -0.221820491 Down 0.42693407 Jun jun proto-oncogene K04448|1|3e-130|469|mmu:16476|transcription factor AP-1 - - - - 14200 1418.28 1027.726667 901.7 -0.188737191 Down 0.426896461 Fhl2 four and a half LIM domains 2 K14380|1|4e-180|633|mmu:14200|four and a half LIM domains protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0031672//A band;GO:0031674//I band;GO:0005924//cell-substrate adherens junction;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0031672//A band;GO:0031674//I band;GO:0005924//cell-substrate adherens junction;GO:0005856//cytoskeleton GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0003206//cardiac chamber morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0001503//ossification;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0009719;GO:0055011//atrial cardiac muscle cell differentiation;GO:0003206//cardiac chamber morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0001503//ossification;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0009719;GO:0055011//atrial cardiac muscle cell differentiation gi|537249409|gb|ERE88203.1|/0/four and a half LIM domain protein 2 [Cricetulus griseus] 233204 2601 15.75 18.59 0.239174942 Up 0.426802437 Tbc1d17 "TBC1 domain family, member 17" K19945|1|0.0|1111|mmu:233204|TBC1 domain family member 17 GO:0044464 - - gi|74208127|dbj|BAE29165.1|/0/unnamed protein product [Mus musculus] 109270 1835 4.43 5.666666667 0.355193642 Up 0.426727218 Prr5 proline rich 5 (renal) K20411|1|0.0|746|mmu:109270|proline-rich protein 5 - - GO:0007010//cytoskeleton organization;GO:0016477//cell migration gi|121583639|ref|NP_666173.4|/0/proline-rich protein 5 [Mus musculus] 78369 907 0.676666667 0.203333333 -1.73459858 Down 0.426642597 Icam4 "intercellular adhesion molecule 4, Landsteiner-Wiener blood group" K06581|1|3e-132|473|mmu:78369|intercellular adhesion molecule 4 GO:0031224//intrinsic component of membrane - GO:0007155//cell adhesion gi|12963855|ref|NP_076381.1|/2.43128e-131/intercellular adhesion molecule 4 precursor [Mus musculus] 63913 3956 3.44 2.49 -0.466262823 Down 0.426548573 Fam129a "family with sequence similarity 129, member A" - GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane - GO:0006412//translation;GO:0001932//regulation of protein phosphorylation;GO:0033554//cellular response to stress gi|241982745|ref|NP_071301.2|/0/protein Niban [Mus musculus] 67305 1214 4.16 5.363333333 0.366546392 Up 0.426435744 Gpx7 glutathione peroxidase 7 K00432|1|2e-94|348|mmu:67305|glutathione peroxidase [EC:1.11.1.9] - GO:0004601//peroxidase activity GO:0006950//response to stress;GO:0044710 "gi|148698795|gb|EDL30742.1|/6.09331e-102/glutathione peroxidase 7, partial [Mus musculus]" 28135 2218.13 13.14 15.58333333 0.246038589 Up 0.426407537 Cep63 centrosomal protein 63 K16763|1|0.0|937|mmu:28135|centrosomal protein CEP63 - - - - 75530 2180 7.03 8.653333333 0.299731288 Up 0.426388732 Lyrm7 LYR motif containing 7 K18170|1|2e-52|209|mmu:75530|complex III assembly factor LYRM7 - - - - 100529082 1344 0.9 1.57 0.802767653 Up 0.426351123 Gm11127 predicted gene 11127 "K06751|1|0.0|708|mmu:100529082|major histocompatibility complex, class I" GO:0044459;GO:0009986//cell surface GO:0005515//protein binding GO:0002484;GO:0002664//regulation of T cell tolerance induction;GO:0009581;GO:0001817//regulation of cytokine production gi|166865459|dbj|BAF76147.2|/0/MHC classIb T15 [Mus musculus] 22759 2763 1.973333333 1.236666667 -0.674177989 Down 0.426304111 Zfp97 zinc finger protein 97 K09228|1|0.0|1213|mmu:22759|KRAB domain-containing zinc finger protein - - - gi|255522853|ref|NP_035895.3|/0/zinc finger protein 97 [Mus musculus] 19270 9190 5.893333333 4.613333333 -0.353274332 Down 0.426257099 Ptprg "protein tyrosine phosphatase, receptor type, G" K16667|1|0.0|2794|mmu:19270|receptor-type tyrosine-protein phosphatase gamma [EC:3.1.3.48] GO:0016021//integral component of membrane;GO:0044421 GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding GO:0007417//central nervous system development;GO:0006470//protein dephosphorylation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0010975//regulation of neuron projection development gi|153791843|ref|NP_033007.2|/0/receptor-type tyrosine-protein phosphatase gamma precursor [Mus musculus] 12192 2984 41.95333333 36.22666667 -0.211733377 Down 0.425993832 Zfp36l1 "zinc finger protein 36, C3H type-like 1" K18753|1|2e-172|609|bom:102287358|butyrate response factor 1 - - - - 654359 598 4.756666667 3.623333333 -0.392633394 Down 0.425928015 Gm12338 "cytochrome c oxidase, subunit VIIc pseudogene" K02272|1|1e-29|131|mmu:12867|cytochrome c oxidase subunit 7c GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0015002//heme-copper terminal oxidase activity GO:0006818//hydrogen transport;GO:0006811//ion transport;GO:0044710 "gi|148692956|gb|EDL24903.1|/4.76494e-41/mCG14133, partial [Mus musculus]" 66506 839 3.85 5.006666667 0.378991961 Up 0.425815187 Psmg3 "proteasome (prosome, macropain) assembly chaperone 3" K11877|1|2e-61|237|mmu:66506|proteasome assembly chaperone 3 GO:0043234//protein complex - - gi|533168513|ref|XP_005397871.1|/1.34609e-61/PREDICTED: proteasome assembly chaperone 3 isoform X1 [Chinchilla lanigera] 108760 3920 3.296666667 2.366666667 -0.478151496 Down 0.425674151 Galnt16 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16 K00710|1|0.0|1102|mmu:108760|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0008376//acetylgalactosaminyltransferase activity GO:0044238//primary metabolic process gi|568978603|ref|XP_006515435.1|/0/PREDICTED: polypeptide N-acetylgalactosaminyltransferase 16 isoform X1 [Mus musculus] 595139 6361 24.41666667 28.49 0.222589363 Up 0.425645944 E030024N20Rik peptidylprolyl isomerase A pseudogene 8 K03767|1|1e-81|188|mmu:268373|peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0016859//cis-trans isomerase activity GO:0019079//viral genome replication;GO:0006996//organelle organization;GO:0009306//protein secretion;GO:0030154//cell differentiation gi|62661794|ref|XP_341364.2|/8.4146e-82/PREDICTED: peptidyl-prolyl cis-trans isomerase A-like [Rattus norvegicus] 630499 1324 1.98 2.846666667 0.523773139 Up 0.42558953 H2-K2 "histocompatibility 2, K region locus 2" "K06751|1|8e-129|280|mmu:15007|major histocompatibility complex, class I" - - - - 666468 2192 4.546666667 5.813333333 0.354556396 Up 0.425523713 Atg4a "autophagy related 4A, cysteine peptidase" K08342|1|0.0|800|mmu:666468|cysteine protease ATG4 [EC:3.4.22.-] - "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process gi|74136555|ref|NP_777364.3|/0/cysteine protease ATG4A [Mus musculus] 76167 1133 4.57 5.836666667 0.352950513 Up 0.425523713 Snrnp35 small nuclear ribonucleoprotein 35 (U11/U12) K13155|1|8e-102|372|mmu:76167|U11/U12 small nuclear ribonucleoprotein 35 kDa protein GO:0005681//spliceosomal complex GO:0036094//small molecule binding;GO:0003676//nucleic acid binding GO:0006396//RNA processing gi|21624627|ref|NP_083808.1|/6.46512e-101/U11/U12 small nuclear ribonucleoprotein 35 kDa protein [Mus musculus] 73067 1140 22.64333333 19.33666667 -0.227747235 Down 0.425486103 Tmem192 transmembrane protein 192 - GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0000323//lytic vacuole - - "gi|148696733|gb|EDL28680.1|/2.55091e-103/RIKEN cDNA 3110005G23, isoform CRA_a, partial [Mus musculus]" 12273 2510.45 3.44 4.543333333 0.401342591 Up 0.425467299 C5ar1 complement component 5a receptor 1 K04010|1|0.0|673|mmu:12273|C5a anaphylatoxin chemotactic receptor GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459 GO:0001847//opsonin receptor activity;GO:0004942//anaphylatoxin receptor activity;GO:0001848//complement binding;GO:0001847//opsonin receptor activity;GO:0004942//anaphylatoxin receptor activity;GO:0001848//complement binding GO:0006366//transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0030902//hindbrain development;GO:0042742//defense response to bacterium;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0008284//positive regulation of cell proliferation;GO:0009887//organ morphogenesis;GO:0002237//response to molecule of bacterial origin;GO:0043410//positive regulation of MAPK cascade;GO:0030595//leukocyte chemotaxis;GO:0002430//complement receptor mediated signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0030902//hindbrain development;GO:0042742//defense response to bacterium;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0008284//positive regulation of cell proliferation;GO:0009887//organ morphogenesis;GO:0002237//response to molecule of bacterial origin;GO:0043410//positive regulation of MAPK cascade;GO:0030595//leukocyte chemotaxis;GO:0002430//complement receptor mediated signaling pathway gi|59814327|ref|NP_031603.2|/0/C5a anaphylatoxin chemotactic receptor 1 [Mus musculus] 216136 2348 9.753333333 11.72333333 0.265415565 Up 0.425410884 Ilvbl ilvB (bacterial acetolactate synthase)-like K11259|1|0.0|1150|mmu:216136|acetolactate synthase-like protein [EC:2.2.1.-] GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding;GO:0003824//catalytic activity;GO:0019842//vitamin binding - "gi|148699779|gb|EDL31726.1|/0/ilvB (bacterial acetolactate synthase)-like, isoform CRA_d, partial [Mus musculus]" 14219 2418 62.94 72.51 0.204202795 Up 0.425260446 Ctgf connective tissue growth factor K06827|1|0.0|711|mmu:14219|connective tissue growth factor GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0044421;GO:0031012//extracellular matrix GO:0005102//receptor binding;GO:0005539//glycosaminoglycan binding;GO:0019838//growth factor binding GO:0010467//gene expression;GO:0001775//cell activation;GO:0001932//regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048870//cell motility;GO:0016337//single organismal cell-cell adhesion;GO:0002062//chondrocyte differentiation;GO:0016049//cell growth;GO:0043410//positive regulation of MAPK cascade;GO:0031960//response to corticosteroid;GO:0006259//DNA metabolic process;GO:0007254//JNK cascade;GO:0045989//positive regulation of striated muscle contraction;GO:0007568//aging;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0031589//cell-substrate adhesion;GO:0001101//response to acid chemical;GO:0043627//response to estrogen;GO:0030198//extracellular matrix organization;GO:0008283//cell proliferation;GO:0032233//positive regulation of actin filament bundle assembly;GO:0009746;GO:0030323//respiratory tube development;GO:0045023//G0 to G1 transition;GO:0006816//calcium ion transport gi|149032916|gb|EDL87771.1|/0/connective tissue growth factor [Rattus norvegicus] 98402 3673 6.923333333 8.52 0.29938662 Up 0.42515702 Sh3bp4 SH3-domain binding protein 4 K20066|1|0.0|1899|mmu:98402|SH3 domain-binding protein 4 GO:0030135//coated vesicle;GO:0012505//endomembrane system GO:0031267//small GTPase binding GO:0006865//amino acid transport;GO:0043087//regulation of GTPase activity;GO:0009968//negative regulation of signal transduction;GO:0008283//cell proliferation;GO:0016192//vesicle-mediated transport;GO:0072665//protein localization to vacuole;GO:0043200//response to amino acid;GO:0006914//autophagy;GO:0016049//cell growth gi|19527036|ref|NP_598577.1|/0/SH3 domain-binding protein 4 [Mus musculus] 50916 2601 10.75 12.87666667 0.260422517 Up 0.425147617 Irx4 Iroquois related homeobox 4 (Drosophila) K19383|1|3e-09|67.0|soc:105204813|homeobox protein TGIF1;K19553|2|4e-09|66.2|crg:105320634|homeobox protein TGIF2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0048869//cellular developmental process;GO:0044767//single-organism developmental process;GO:0007275//multicellular organism development;GO:0006366//transcription from RNA polymerase II promoter gi|9256547|ref|NP_061373.1|/0/iroquois-class homeodomain protein IRX-4 [Mus musculus] 74147 3010 13.04 10.91333333 -0.256852048 Down 0.425147617 Ehhadh "enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase" "K07514|1|0.0|1370|mmu:74147|enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]" GO:0031981//nuclear lumen;GO:0042579//microbody "GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0005515//protein binding;GO:0036094//small molecule binding;GO:0048037//cofactor binding;GO:0016836//hydro-lyase activity" GO:0006473//protein acetylation;GO:0009062//fatty acid catabolic process;GO:0006732 gi|31541815|ref|NP_076226.2|/0/peroxisomal bifunctional enzyme [Mus musculus] 100499530 80 0.833333333 1.483333333 0.831877241 Up 0.425091203 Mir1906-2 microRNA 1906-2 - - - - - 100316809 80 0.833333333 1.483333333 0.831877241 Up 0.425091203 Mir1906-1 microRNA 1906-1 - - - - - 252903 2892 2.926666667 3.946666667 0.431376236 Up 0.425062996 Ap1s3 "adaptor-related protein complex AP-1, sigma 3" K12395|1|2e-84|310|chx:102184293|AP-1 complex subunit sigma-3 GO:0012505//endomembrane system;GO:0043234//protein complex;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle GO:0022892//substrate-specific transporter activity GO:0016192//vesicle-mediated transport;GO:0015031//protein transport gi|803217203|ref|XP_011968957.1|/1.46513e-83/PREDICTED: AP-1 complex subunit sigma-3 isoform X2 [Ovis aries musimon] 20316 1284 24.54666667 28.54333333 0.217626699 Up 0.425044191 Sdf2 stromal cell derived factor 2 K15692|1|3e-15|85.5|tsp:Tsp_05947|E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27];K00728|2|1e-09|66.6|bmor:101741371|dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109] - - - gi|226958306|ref|NP_033169.3|/4.85393e-103/stromal cell-derived factor 2 precursor [Mus musculus] 72042 1642 7.683333333 9.386666667 0.288880583 Up 0.425044191 Cotl1 coactosin-like 1 (Dictyostelium) - GO:0043232;GO:0005635//nuclear envelope GO:0008092//cytoskeletal protein binding GO:0006952//defense response "gi|148679670|gb|EDL11617.1|/2.59011e-118/coactosin-like 1 (Dictyostelium), isoform CRA_b, partial [Mus musculus]" 13849 1754 34.63666667 40.17 0.213818365 Up 0.42492196 Ephx1 "epoxide hydrolase 1, microsomal" K01253|1|0.0|943|mmu:13849|microsomal epoxide hydrolase [EC:3.3.2.9] - - - - 18585 2061.01 1.4 2.16 0.625604485 Up 0.42472451 Pde9a phosphodiesterase 9A "K13761|1|0.0|1077|mmu:18585|high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9 [EC:3.1.4.35]" GO:0043231//intracellular membrane-bounded organelle;GO:0001726//ruffle;GO:0044444//cytoplasmic part;GO:0043025//neuronal cell body "GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity" GO:0007599//hemostasis;GO:0019935//cyclic-nucleotide-mediated signaling "gi|148708411|gb|EDL40358.1|/0/phosphodiesterase 9A, isoform CRA_b, partial [Mus musculus]" 19734 2351 0.333333333 0.843333333 1.339137385 Up 0.424583474 Rgs16 regulator of G-protein signaling 16 K16449|1|3e-99|365|mmu:19734|regulator of G-protein signaling - - - gi|33416754|gb|AAH55459.1|/2.73963e-98/Regulator of G-protein signaling 16 [Mus musculus] 329554 1097 4.94 6.246666667 0.338575505 Up 0.424555267 Gm826 predicted gene 826 - - - - gi|568917589|ref|XP_006499854.1|/1.87086e-72/PREDICTED: uncharacterized protein LOC329554 isoform X1 [Mus musculus] 67080 834 0.536666667 0.11 -2.286522759 Down 0.424489451 1700019D03Rik RIKEN cDNA 1700019D03 gene - GO:0016020//membrane - - gi|21450635|ref|NP_659202.1|/1.21153e-54/small membrane A-kinase anchor protein [Mus musculus] 17330 2619 4.566666667 5.826666667 0.351529292 Up 0.424489451 Minpp1 multiple inositol polyphosphate histidine phosphatase 1 "K03103|1|0.0|946|mmu:17330|multiple inositol-polyphosphate phosphatase / 2,3-bisphosphoglycerate 3-phosphatase [EC:3.1.3.62 3.1.3.80]" GO:0044432;GO:0016020//membrane GO:0034416//bisphosphoglycerate phosphatase activity;GO:0052827;GO:0004446//inositol-hexakisphosphate phosphatase activity;GO:0052743 GO:0048017//inositol lipid-mediated signaling gi|6754698|ref|NP_034929.1|/0/multiple inositol polyphosphate phosphatase 1 precursor [Mus musculus] 14874 1688.97 28.15 24.2 -0.218127875 Down 0.424480048 Gstz1 glutathione transferase zeta 1 (maleylacetoacetate isomerase) K01800|1|5e-118|427|mmu:14874|maleylacetoacetate isomerase [EC:5.2.1.2] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0042802//identical protein binding;GO:0016859//cis-trans isomerase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0042802//identical protein binding;GO:0016859//cis-trans isomerase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0042802//identical protein binding;GO:0016859//cis-trans isomerase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups" GO:0006790//sulfur compound metabolic process;GO:0006558//L-phenylalanine metabolic process;GO:0006570//tyrosine metabolic process;GO:0006790//sulfur compound metabolic process;GO:0006558//L-phenylalanine metabolic process;GO:0006570//tyrosine metabolic process;GO:0006790//sulfur compound metabolic process;GO:0006558//L-phenylalanine metabolic process;GO:0006570//tyrosine metabolic process gi|6754092|ref|NP_034493.1|/3.87102e-117/maleylacetoacetate isomerase isoform 1 [Mus musculus] 21388 3941 18.90666667 22.14333333 0.227977382 Up 0.424423634 Tbx5 T-box 5 K10179|1|0.0|1029|mmu:21388|T-box protein 5 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding GO:0048729//tissue morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0003164;GO:0003230//cardiac atrium development;GO:0030326//embryonic limb morphogenesis;GO:0008285//negative regulation of cell proliferation;GO:0007154//cell communication;GO:0048738//cardiac muscle tissue development;GO:0008284//positive regulation of cell proliferation;GO:0003211//cardiac ventricle formation;GO:0030323//respiratory tube development;GO:0012502//induction of programmed cell death;GO:0003171//atrioventricular valve development;GO:0010002//cardioblast differentiation;GO:0016477//cell migration gi|568937097|ref|XP_006530342.1|/0/PREDICTED: T-box transcription factor TBX5 isoform X2 [Mus musculus] 330188 2053 0.946666667 0.413333333 -1.195550809 Down 0.424386024 Ccdc63 coiled-coil domain containing 63 K12478|1|7e-09|65.5|gja:107118648|early endosome antigen 1;K10352|2|1e-08|64.7|ola:101154782|myosin heavy chain;K20283|3|1e-08|64.3|mde:101892550|golgin subfamily A member 4;K17388|4|1e-07|61.6|xma:102226221|Rho-associated protein kinase 2 [EC:2.7.11.1] - - - - 100040671 1991 0.113333333 0.546666667 2.270089163 Up 0.424386024 Gm2897 predicted gene 2897 "K03844|1|3e-17|92.4|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - gi|755546838|ref|XP_011243025.1|/1.18281e-99/PREDICTED: alpha6-takusan-like isoform X2 [Mus musculus] 102238433 5121 0.943333333 0.41 -1.202143737 Down 0.424386024 Gm28042 "predicted gene, 28042" K16342|1|0.0|1491|mmu:211429|cytosolic phospholipase A2 [EC:3.1.1.4] - GO:0004620//phospholipase activity - gi|167900427|ref|NP_663353.3|/0/cytosolic phospholipase A2 beta [Mus musculus] 71787 1146 14.91666667 17.64 0.241925379 Up 0.424263793 Trnau1ap tRNA selenocysteine 1 associated protein 1 K13201|1|1e-16|90.1|obi:106868113|nucleolysin TIA-1/TIAR;K13126|4|3e-14|82.0|nle:100607129|polyadenylate-binding protein GO:0043231//intracellular membrane-bounded organelle GO:0036094//small molecule binding;GO:0003676//nucleic acid binding GO:0006451//translational readthrough gi|62821783|ref|NP_082201.2|/5.48764e-140/tRNA selenocysteine 1-associated protein 1 [Mus musculus] 192289 2264 5.266666667 6.636666667 0.333568663 Up 0.424197977 Tmlhe "trimethyllysine hydroxylase, epsilon" K00474|1|0.0|895|mmu:192289|trimethyllysine dioxygenase [EC:1.14.11.8] GO:0044429 "GO:0019842//vitamin binding;GO:0043169//cation binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0006578//amino-acid betaine biosynthetic process;GO:0044710;GO:0043086//negative regulation of catalytic activity "gi|20270297|ref|NP_620097.1|/0/trimethyllysine dioxygenase, mitochondrial [Mus musculus]" 18624 1856 12.71666667 15.08 0.245915872 Up 0.424113355 Pepd peptidase D K14213|1|0.0|982|mmu:18624|Xaa-Pro dipeptidase [EC:3.4.13.9] - GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity GO:0032963//collagen metabolic process;GO:0019538//protein metabolic process gi|170650724|ref|NP_032846.2|/0/xaa-Pro dipeptidase [Mus musculus] 14791 1086 34.56333333 39.94666667 0.208832763 Up 0.424047538 Emg1 EMG1 N1-specific pseudouridine methyltransferase K14568|1|9e-137|488|mmu:14791|rRNA small subunit pseudouridine methyltransferase Nep1 [EC:2.1.1.260] - - - - 15404 1952 0.033333333 0.386666667 3.5360529 Up 0.424019331 Hoxa7 homeobox A7 K09307|1|3e-123|445|mmu:15404|homeobox protein HoxA/B7 GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0002683//negative regulation of immune system process;GO:0001952//regulation of cell-matrix adhesion;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0048562//embryonic organ morphogenesis;GO:0003002//regionalization;GO:0030216//keratinocyte differentiation gi|6754234|ref|NP_034585.1|/2.15919e-122/homeobox protein Hox-A7 [Mus musculus] 626175 626 0.116666667 0.55 2.237039197 Up 0.424019331 Gm6654 predicted pseudogene 6654 K02976|1|2e-39|164|rno:100360508|small subunit ribosomal protein S26e GO:0030529//intracellular ribonucleoprotein complex - GO:0010467//gene expression gi|564315719|ref|XP_003752685.2|/1.4535e-38/PREDICTED: 40S ribosomal protein S26-like [Rattus norvegicus] 12654 1704 0.01 0.306666667 4.938599455 Up 0.423840686 Chil1 chitinase-like 1 K17523|1|0.0|738|mmu:12654|chitinase-3-like protein 1/2 GO:0043231//intracellular membrane-bounded organelle;GO:0044421;GO:0031012//extracellular matrix "GO:0005198//structural molecule activity;GO:0097367//carbohydrate derivative binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds" GO:0001501//skeletal system development;GO:0001525//angiogenesis;GO:0009605//response to external stimulus;GO:0032637//interleukin-8 production;GO:0032147//activation of protein kinase activity;GO:0034612//response to tumor necrosis factor;GO:0030323//respiratory tube development;GO:0006026;GO:0070555//response to interleukin-1;GO:0043410//positive regulation of MAPK cascade;GO:0006952//defense response gi|224809461|ref|NP_031721.2|/0/chitinase-3-like protein 1 precursor [Mus musculus] 72167 1856 1.303333333 2.046666667 0.651070048 Up 0.423746662 Thumpd2 THUMP domain containing 2 K11251|1|3e-16|89.7|tsp:Tsp_07029|histone H2A - - - gi|254553438|ref|NP_082414.1|/0/THUMP domain-containing protein 2 [Mus musculus] 227102 1849 4.233333333 5.443333333 0.362696294 Up 0.42369965 Ormdl1 ORM1-like 1 (S. cerevisiae) K12667|1|1e-35|153|smm:Smp_144800|oligosaccharyltransferase complex subunit delta (ribophorin II) GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0006665//sphingolipid metabolic process gi|625224973|ref|XP_007652017.1|/7.49726e-85/PREDICTED: ORM1-like protein 1 isoform X1 [Cricetulus griseus] 105841 5299 5.45 4.236666667 -0.363326605 Down 0.42369965 Dennd3 DENN/MADD domain containing 3 K20162|1|0.0|2503|mmu:105841|DENN domain-containing protein 3 - GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0030163//protein catabolic process gi|50510677|dbj|BAD32324.1|/0/mKIAA0870 protein [Mus musculus] 19247 5621.15 68.56333333 59.83333333 -0.196487812 Down 0.423586822 Ptpn11 "protein tyrosine phosphatase, non-receptor type 11" K07293|1|0.0|1171|mmu:19247|tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48] GO:0032991//macromolecular complex;GO:0032432//actin filament bundle;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0032432//actin filament bundle;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0051427//hormone receptor binding;GO:0030674//protein binding, bridging;GO:0004725//protein tyrosine phosphatase activity;GO:0019899//enzyme binding;GO:0051427//hormone receptor binding;GO:0030674//protein binding, bridging;GO:0004725//protein tyrosine phosphatase activity;GO:0019899//enzyme binding" GO:0006639//acylglycerol metabolic process;GO:0007548//sex differentiation;GO:0007507//heart development;GO:0006470//protein dephosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0046326//positive regulation of glucose import;GO:0030252//growth hormone secretion;GO:0035264//multicellular organism growth;GO:0030155//regulation of cell adhesion;GO:0006611//protein export from nucleus;GO:0033500//carbohydrate homeostasis;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007417//central nervous system development;GO:0050796//regulation of insulin secretion;GO:0043583//ear development;GO:0043400//cortisol secretion;GO:0006468//protein phosphorylation;GO:0006639//acylglycerol metabolic process;GO:0007548//sex differentiation;GO:0007507//heart development;GO:0006470//protein dephosphorylation;GO:0046326//positive regulation of glucose import;GO:0030252//growth hormone secretion;GO:0035264//multicellular organism growth;GO:0006935//chemotaxis;GO:0006974//cellular response to DNA damage stimulus;GO:0030155//regulation of cell adhesion;GO:0006611//protein export from nucleus;GO:0007599//hemostasis;GO:0033500//carbohydrate homeostasis;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007417//central nervous system development;GO:0050796//regulation of insulin secretion;GO:0038127//ERBB signaling pathway;GO:0043583//ear development;GO:0043400//cortisol secretion;GO:0006468//protein phosphorylation;GO:0031294//lymphocyte costimulation gi|6755228|ref|NP_035332.1|/0/tyrosine-protein phosphatase non-receptor type 11 isoform a [Mus musculus] 14775 1066 57.08 65.78333333 0.204736779 Up 0.423511603 Gpx1 glutathione peroxidase 1 K00432|1|4e-108|393|mmu:14775|glutathione peroxidase [EC:1.11.1.9] - - - - 16495 3494 3.576666667 4.683333333 0.388920054 Up 0.423492798 Kcna7 "potassium voltage-gated channel, shaker-related subfamily, member 7" K04880|1|0.0|796|mmu:16495|potassium voltage-gated channel Shaker-related subfamily A member 7 - - - gi|3004907|gb|AAC12271.1|/0/voltage-gated potassium channel Kv1.7 [Mus musculus] 234214 4409.1 67.76666667 59.11666667 -0.197010885 Down 0.423408176 Sorbs2 sorbin and SH3 domain containing 2 K06086|1|4e-112|409|cjo:107315825|sorbin and SH3 domain containing 1 - - - - 100213 5301.1 26.83 22.97333333 -0.223886854 Down 0.423398774 Rusc2 RUN and SH3 domain containing 2 - - - - gi|28972183|dbj|BAC65545.1|/0/mKIAA0375 protein [Mus musculus] 68033 778 39.55 34.30666667 -0.205188738 Down 0.423361164 Cox19 cytochrome c oxidase assembly protein 19 K18183|1|8e-50|199|mmu:68033|cytochrome c oxidase assembly protein subunit 19 GO:0044424 - - "gi|148687213|gb|EDL19160.1|/3.18048e-51/RIKEN cDNA 2810437L13, isoform CRA_c, partial [Mus musculus]" 72392 2988.18 5.26 6.616666667 0.331041802 Up 0.42330475 Tmem175 transmembrane protein 175 - - - - - 106393 4978 275.2433333 241.9466667 -0.186018558 Down 0.423285945 Srl sarcalumenin K12483|1|3e-62|243|tad:TRIADDRAFT_18691|EH domain-containing protein 1;K12476|3|2e-59|234|ola:101160952|EH domain-containing protein 3 GO:0005783//endoplasmic reticulum GO:0032550 - gi|34328417|ref|NP_780556.2|/0/sarcalumenin precursor [Mus musculus] 21987 1267 6.7 8.27 0.303726234 Up 0.423248336 Tpd52l1 tumor protein D52-like 1 - GO:0044444//cytoplasmic part GO:0046983//protein dimerization activity;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0042802//identical protein binding "GO:0000737//DNA catabolic process, endonucleolytic;GO:0044772//mitotic cell cycle phase transition;GO:0006915//apoptotic process;GO:0007254//JNK cascade;GO:0012502//induction of programmed cell death;GO:0043405//regulation of MAP kinase activity" gi|568965335|ref|XP_006512766.1|/2.19146e-124/PREDICTED: tumor protein D53 isoform X1 [Mus musculus] 66848 3954 66.28 57.69 -0.200252339 Down 0.423248336 Fuca2 "fucosidase, alpha-L- 2, plasma" K01206|1|0.0|960|mmu:66848|alpha-L-fucosidase [EC:3.2.1.51] - GO:0015928//fucosidase activity GO:0019318//hexose metabolic process gi|12842976|dbj|BAB25809.1|/0/unnamed protein product [Mus musculus] 52231 2627.59 8.476666667 10.27 0.27686722 Up 0.423220129 Ankzf1 ankyrin repeat and zinc finger domain containing 1 - GO:0044464 GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding - gi|390198551|ref|NP_001254549.1|/3.50285e-71/ankyrin repeat and zinc finger domain-containing protein 1 isoform 2 [Mus musculus] 107328 1168 12.52 14.85333333 0.24655217 Up 0.423079093 Trpt1 tRNA phosphotransferase 1 K10669|1|7e-69|263|mmu:107328|2'-phosphotransferase [EC:2.7.1.160] - GO:0016740//transferase activity;GO:0016740//transferase activity "GO:0006399//tRNA metabolic process;GO:0001932//regulation of protein phosphorylation;GO:0000394//RNA splicing, via endonucleolytic cleavage and ligation;GO:0006399//tRNA metabolic process;GO:0001932//regulation of protein phosphorylation;GO:0000394//RNA splicing, via endonucleolytic cleavage and ligation" gi|224994263|ref|NP_705825.2|/8.71522e-141/tRNA 2'-phosphotransferase 1 [Mus musculus] 56496 1763 3.243333333 4.303333333 0.407977291 Up 0.422844033 Tspan6 tetraspanin 6 K17295|1|3e-140|501|mmu:56496|tetraspanin-6 GO:0031224//intrinsic component of membrane - GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|31560378|ref|NP_062630.2|/2.91335e-139/tetraspanin-6 [Mus musculus] 72029 1901.99 12.29 14.61333333 0.249800382 Up 0.422806424 Cnpy3 canopy FGF signaling regulator 3 - - - - - 239102 8738 5.356666667 4.16 -0.364751995 Down 0.422778217 Zfhx2 zinc finger homeobox 2 K09379|1|0.0|3945|mmu:239102|zinc finger homeobox protein 2 - - - gi|85986589|ref|NP_001034287.1|/0/zinc finger homeobox protein 2 [Mus musculus] 65963 1189.74 23.44333333 27.24666667 0.216902026 Up 0.422693595 Tmem176b transmembrane protein 176B - GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane - GO:0045596//negative regulation of cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0045596//negative regulation of cell differentiation gi|12746434|ref|NP_075543.1|/1.48435e-136/transmembrane protein 176B [Mus musculus] 15519 2850 27.03 23.23 -0.218572358 Down 0.422693595 Hsp90aa1 "heat shock protein 90, alpha (cytosolic), class A member 1" K04079|1|0.0|1244|mmu:15519|molecular chaperone HtpG GO:0032991//macromolecular complex;GO:0005903//brush border;GO:0044459;GO:0048770;GO:0044297//cell body GO:0030234//enzyme regulator activity;GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0032551;GO:0019902//phosphatase binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0042802//identical protein binding;GO:0019904//protein domain specific binding;GO:0032558//adenyl deoxyribonucleotide binding;GO:0003723//RNA binding "GO:0043623//cellular protein complex assembly;GO:0006809//nitric oxide biosynthetic process;GO:0006626//protein targeting to mitochondrion;GO:0010658;GO:0006970//response to osmotic stress;GO:0045065//cytotoxic T cell differentiation;GO:0016477//cell migration;GO:0009154//purine ribonucleotide catabolic process;GO:0045989//positive regulation of striated muscle contraction;GO:0000060//protein import into nucleus, translocation;GO:0010591//regulation of lamellipodium assembly;GO:0008361//regulation of cell size;GO:0048545//response to steroid hormone;GO:0035966//response to topologically incorrect protein;GO:0006457//protein folding" gi|74147335|dbj|BAE27553.1|/0/unnamed protein product [Mus musculus] 22038 2141 9.163333333 11.07333333 0.273145166 Up 0.422684193 Plscr1 phospholipid scramblase 1 - GO:0031981//nuclear lumen;GO:0016021//integral component of membrane;GO:0044444//cytoplasmic part "GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0019904//protein domain specific binding;GO:0003676//nucleic acid binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0070851//growth factor receptor binding" GO:0030097//hemopoiesis;GO:0010912;GO:0006915//apoptotic process;GO:0006869//lipid transport;GO:0019079//viral genome replication;GO:0007009//plasma membrane organization;GO:0031349//positive regulation of defense response;GO:0006658//phosphatidylserine metabolic process;GO:0009411//response to UV;GO:0002526//acute inflammatory response;GO:0002431//Fc receptor mediated stimulatory signaling pathway;GO:0043393//regulation of protein binding;GO:0002252;GO:0006366//transcription from RNA polymerase II promoter;GO:0035556//intracellular signal transduction;GO:0034097//response to cytokine;GO:0002694;GO:0032496//response to lipopolysaccharide gi|194328695|ref|NP_035766.2|/7.7661e-129/phospholipid scramblase 1 [Mus musculus] 108159 2817 5.27 6.616666667 0.32830164 Up 0.422655986 Ubxn8 UBX domain protein 8 - - - - gi|85861247|ref|NP_848763.2|/6.77821e-123/UBX domain-containing protein 8 [Mus musculus] 110095 2821 1.866666667 1.153333333 -0.694654789 Down 0.422590169 Pygl liver glycogen phosphorylase K00688|1|0.0|1671|mmu:110095|starch phosphorylase [EC:2.4.1.1] GO:0044424;GO:0016020//membrane GO:0032550;GO:0002054;GO:0043168//anion binding;GO:0042802//identical protein binding;GO:0005496//steroid binding;GO:0004645//phosphorylase activity GO:0046390//ribose phosphate biosynthetic process;GO:0005977//glycogen metabolic process;GO:0033500//carbohydrate homeostasis "gi|268836255|ref|NP_573461.2|/0/glycogen phosphorylase, liver form [Mus musculus]" 100379610 1243 3.746666667 2.766666667 -0.437458794 Down 0.422533755 Gm11651 predicted gene 11651 K01283|1|9e-17|90.5|mmu:11421|peptidyl-dipeptidase A [EC:3.4.15.1] - - - - 69478 612 14.44333333 12.13333333 -0.251427786 Down 0.422524352 2300009A05Rik RIKEN cDNA 2300009A05 gene K11255|1|7e-10|65.9|ccw:104692824|nuclear receptor coactivator 2 - - - "gi|148694092|gb|EDL26039.1|/1.01999e-94/mCG9285, partial [Mus musculus]" 12317 1943 199.8366667 228.36 0.19248865 Up 0.422496145 Calr calreticulin K08057|1|0.0|650|mmu:12317|calreticulin GO:0009986//cell surface;GO:0030529//intracellular ribonucleoprotein complex;GO:0005788//endoplasmic reticulum lumen;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030141//secretory granule;GO:0044421 GO:0035258//steroid hormone receptor binding;GO:0033218//amide binding;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding GO:0048232//male gamete generation;GO:0007126//meiotic nuclear division;GO:0010770//positive regulation of cell morphogenesis involved in differentiation;GO:0033365//protein localization to organelle;GO:0051726//regulation of cell cycle;GO:0035051//cardiocyte differentiation;GO:0007569//cell aging;GO:0010226//response to lithium ion;GO:0030182//neuron differentiation;GO:0006886//intracellular protein transport;GO:0002397//MHC class I protein complex assembly;GO:0043627//response to estrogen;GO:0006260//DNA replication;GO:0009968//negative regulation of signal transduction;GO:0008283//cell proliferation;GO:0002407//dendritic cell chemotaxis;GO:0006366//transcription from RNA polymerase II promoter;GO:0030036//actin cytoskeleton organization;GO:0006412//translation;GO:0006457//protein folding;GO:0031647//regulation of protein stability;GO:0006909//phagocytosis gi|74200069|dbj|BAE22866.1|/0/unnamed protein product [Mus musculus] 74370 7046 9.1 7.446666667 -0.289271765 Down 0.422411524 Rptor "regulatory associated protein of MTOR, complex 1" K07204|1|0.0|2620|rno:287871|regulatory associated protein of mTOR GO:0043005//neuron projection;GO:0044297//cell body;GO:0000323//lytic vacuole;GO:0043234//protein complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0000323//lytic vacuole;GO:0043234//protein complex GO:0001016//RNA polymerase III regulatory region DNA binding;GO:0001025//RNA polymerase III transcription factor binding;GO:0019900//kinase binding;GO:0001016//RNA polymerase III regulatory region DNA binding;GO:0001025//RNA polymerase III transcription factor binding;GO:0019900//kinase binding GO:0006383//transcription from RNA polymerase III promoter;GO:0040007//growth;GO:0001935//endothelial cell proliferation;GO:0032535//regulation of cellular component size;GO:0009967//positive regulation of signal transduction;GO:0045860//positive regulation of protein kinase activity;GO:0043200//response to amino acid;GO:0031667//response to nutrient levels;GO:0035556//intracellular signal transduction;GO:0006383//transcription from RNA polymerase III promoter;GO:0040007//growth;GO:0001935//endothelial cell proliferation;GO:0032535//regulation of cellular component size;GO:0009967//positive regulation of signal transduction;GO:0045860//positive regulation of protein kinase activity;GO:0043200//response to amino acid;GO:0031667//response to nutrient levels;GO:0035556//intracellular signal transduction "gi|133777706|gb|AAI18972.1|/0/4932417H02Rik protein, partial [Mus musculus]" 73847 1708.49 2.846666667 3.843333333 0.433084538 Up 0.422383316 Fam110a "family with sequence similarity 110, member A" - GO:0044424;GO:0044424;GO:0044424;GO:0044424 - - "gi|148673997|gb|EDL05944.1|/1.0933e-163/RIKEN cDNA 5430432M24, isoform CRA_d, partial [Mus musculus]" 16969 5373 17.25 14.62 -0.238653051 Down 0.422373914 Zbtb7a zinc finger and BTB domain containing 7a K10494|1|0.0|825|mmu:16969|zinc finger and BTB domain-containing protein 7 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0019899//enzyme binding GO:0001501//skeletal system development;GO:0002761//regulation of myeloid leukocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter gi|568966793|ref|XP_006513342.1|/0/PREDICTED: zinc finger and BTB domain-containing protein 7A isoform X2 [Mus musculus] 11832 2524 22.95 26.73333333 0.220145582 Up 0.422364512 Aqp7 aquaporin 7 K08771|1|4e-164|581|mmu:11832|aquaporin-7 GO:0030054//cell junction;GO:0032991//macromolecular complex;GO:0016021//integral component of membrane;GO:0005903//brush border;GO:0044424 GO:0005372//water transmembrane transporter activity;GO:0015204//urea transmembrane transporter activity;GO:0015168//glycerol transmembrane transporter activity;GO:0022829//wide pore channel activity GO:0044763;GO:0003097//renal water transport;GO:0042221//response to chemical;GO:0048232//male gamete generation;GO:0008643//carbohydrate transport;GO:0015840//urea transport;GO:0044237//cellular metabolic process gi|6680712|ref|NP_031499.1|/3.4483e-163/aquaporin-7 [Mus musculus] 20499 5131 63.86666667 55.74666667 -0.196177613 Down 0.422148257 Slc12a7 "solute carrier family 12, member 7" "K13627|1|0.0|1965|mmu:20499|solute carrier family 12 (potassium/chloride transporter), member 7" GO:0031224//intrinsic component of membrane GO:0015377//cation:chloride symporter activity GO:0019725//cellular homeostasis;GO:0030001//metal ion transport gi|47847414|dbj|BAD21379.1|/0/mFLJ00098 protein [Mus musculus] 320466 1780 2.81 1.956666667 -0.522172128 Down 0.422138854 A230103J11Rik RIKEN cDNA A230103J11 gene K18727|1|2e-35|152|mdo:100010096|transportin-2 - - - - 80291 1278 3.903333333 5.06 0.374430715 Up 0.422016623 Rilpl2 Rab interacting lysosomal protein-like 2 K20173|1|9e-14|80.5|dre:780843|RILP-like protein 1 GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0005515//protein binding - gi|13385074|ref|NP_084535.1|/1.04365e-97/RILP-like protein 2 [Mus musculus] 73341 4580 17.15333333 14.54333333 -0.238130983 Down 0.421932002 Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 K05729|1|0.0|1451|mmu:73341|Rho guanine nucleotide exchange factor 6 GO:0031252//cell leading edge;GO:0044424 GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding GO:0007266//Rho protein signal transduction;GO:0030031//cell projection assembly gi|270132620|ref|NP_690014.2|/0/rho guanine nucleotide exchange factor 6 [Mus musculus] 338369 1669 1.446666667 2.203333333 0.606955229 Up 0.421913197 Tmem220 transmembrane protein 220 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|28893573|ref|NP_796366.1|/6.55355e-101/transmembrane protein 220 isoform 1 precursor [Mus musculus] 17751 538 1.46 2.223333333 0.606755892 Up 0.421913197 Mt3 metallothionein 3 K14740|1|2e-09|63.5|cfa:100855992|metallothionein 3 - - - - 54128 1802 22.81 26.53666667 0.218320715 Up 0.421762759 Pmm2 phosphomannomutase 2 K17497|1|2e-140|502|mmu:54128|phosphomannomutase [EC:5.4.2.8] GO:0044297//cell body;GO:0044424 "GO:0016868//intramolecular transferase activity, phosphotransferases" GO:0006013//mannose metabolic process gi|8393988|ref|NP_058577.1|/1.34647e-139/phosphomannomutase 2 [Mus musculus] 79059 724 10.47666667 12.51666667 0.256670636 Up 0.421743954 Nme3 NME/NM23 nucleoside diphosphate kinase 3 K00940|1|2e-93|343|mmu:79059|nucleoside-diphosphate kinase [EC:2.7.4.6] GO:0043231//intracellular membrane-bounded organelle "GO:0043169//cation binding;GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0009209;GO:0009152//purine ribonucleotide biosynthetic process;GO:0009132//nucleoside diphosphate metabolic process gi|255308888|ref|NP_062704.2|/1.42071e-92/nucleoside diphosphate kinase 3 precursor [Mus musculus] 11593 1307 14.43666667 17.03333333 0.238623119 Up 0.421696942 Aga aspartylglucosaminidase K01444|1|6e-175|615|mmu:11593|N4-(beta-N-acetylglucosaminyl)-L-asparaginase [EC:3.5.1.26] GO:0000323//lytic vacuole;GO:0000323//lytic vacuole "GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005515//protein binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005515//protein binding" GO:0006464//cellular protein modification process;GO:0010467//gene expression;GO:0006464//cellular protein modification process;GO:0010467//gene expression gi|326439050|ref|NP_001191983.1|/1.91627e-176/N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase isoform 2 precursor [Mus musculus] 433466 1383 3.196666667 4.243333333 0.408629699 Up 0.421631126 Jmjd7 jumonji domain containing 7 K19219|1|0.0|642|mmu:433466|jumonji domain-containing protein 7 - - - "gi|887492346|pdb|4QU2|A/0/Chain A, The Structure Of Jmjd7 With Alpha-kg" 22329 3398 2.59 3.536666667 0.449438153 Up 0.421508895 Vcam1 vascular cell adhesion molecule 1 K06527|1|0.0|1464|mmu:22329|vascular cell adhesion molecule 1 GO:0015629//actin cytoskeleton;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0042995//cell projection;GO:0044421;GO:0005886//plasma membrane GO:0005102//receptor binding GO:0071363//cellular response to growth factor stimulus;GO:0001892//embryonic placenta development;GO:0022406//membrane docking;GO:0034612//response to tumor necrosis factor;GO:0014070//response to organic cyclic compound;GO:0010038//response to metal ion;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0097305//response to alcohol;GO:0007159//leukocyte cell-cell adhesion;GO:0009314//response to radiation;GO:0002237//response to molecule of bacterial origin;GO:0001678//cellular glucose homeostasis;GO:0031667//response to nutrient levels;GO:0042098//T cell proliferation gi|170295823|ref|NP_035823.3|/0/vascular cell adhesion protein 1 precursor [Mus musculus] 11857 1187 22.30333333 26.00333333 0.221437229 Up 0.42145248 Arhgdib "Rho, GDP dissociation inhibitor (GDI) beta" K12462|1|7e-114|412|mmu:11857|Rho GDP-dissociation inhibitor - - - - 666048 6617 37.01 32.09 -0.205791346 Down 0.421283237 Trabd2b TraB domain containing 2B - - - - - 216869 1837.9 9.17 11.05333333 0.269487867 Up 0.421264433 Arrb2 "arrestin, beta 2" K04439|1|0.0|748|mmu:216869|beta-arrestin GO:0031982//vesicle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0031982//vesicle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0031982//vesicle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0031982//vesicle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane GO:0031701//angiotensin receptor binding;GO:0031690//adrenergic receptor binding;GO:0050780//dopamine receptor binding;GO:0031821//G-protein coupled serotonin receptor binding;GO:0019901//protein kinase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0031701//angiotensin receptor binding;GO:0031690//adrenergic receptor binding;GO:0050780//dopamine receptor binding;GO:0031821//G-protein coupled serotonin receptor binding;GO:0019901//protein kinase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0031701//angiotensin receptor binding;GO:0031690//adrenergic receptor binding;GO:0050780//dopamine receptor binding;GO:0031821//G-protein coupled serotonin receptor binding;GO:0019901//protein kinase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0031701//angiotensin receptor binding;GO:0031690//adrenergic receptor binding;GO:0050780//dopamine receptor binding;GO:0031821//G-protein coupled serotonin receptor binding;GO:0019901//protein kinase binding;GO:0044389//ubiquitin-like protein ligase binding "GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0001541//ovarian follicle development;GO:0032611//interleukin-1 beta production;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0016567//protein ubiquitination;GO:0006198//cAMP catabolic process;GO:0019233//sensory perception of pain;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0043410//positive regulation of MAPK cascade;GO:0001963//synaptic transmission, dopaminergic;GO:0001934//positive regulation of protein phosphorylation;GO:0006935//chemotaxis;GO:0008344//adult locomotory behavior;GO:0001911;GO:0045184//establishment of protein localization;GO:0007417//central nervous system development;GO:0002090//regulation of receptor internalization;GO:0002224//toll-like receptor signaling pathway;GO:0043087//regulation of GTPase activity;GO:0001818//negative regulation of cytokine production;GO:0006816//calcium ion transport;GO:0006171//cAMP biosynthetic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0001541//ovarian follicle development;GO:0032611//interleukin-1 beta production;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0016567//protein ubiquitination;GO:0006198//cAMP catabolic process;GO:0019233//sensory perception of pain;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0043410//positive regulation of MAPK cascade;GO:0001963//synaptic transmission, dopaminergic;GO:0001934//positive regulation of protein phosphorylation;GO:0006935//chemotaxis;GO:0008344//adult locomotory behavior;GO:0001911;GO:0045184//establishment of protein localization;GO:0007417//central nervous system development;GO:0002090//regulation of receptor internalization;GO:0002224//toll-like receptor signaling pathway;GO:0043087//regulation of GTPase activity;GO:0001818//negative regulation of cytokine production;GO:0006816//calcium ion transport;GO:0006171//cAMP biosynthetic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0001541//ovarian follicle development;GO:0032611//interleukin-1 beta production;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0016567//protein ubiquitination;GO:0006198//cAMP catabolic process;GO:0019233//sensory perception of pain;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0043410//positive regulation of MAPK cascade;GO:0001963//synaptic transmission, dopaminergic;GO:0001934//positive regulation of protein phosphorylation;GO:0006935//chemotaxis;GO:0008344//adult locomotory behavior;GO:0001911;GO:0045184//establishment of protein localization;GO:0007417//central nervous system development;GO:0002090//regulation of receptor internalization;GO:0002224//toll-like receptor signaling pathway;GO:0043087//regulation of GTPase activity;GO:0001818//negative regulation of cytokine production;GO:0006816//calcium ion transport;GO:0006171//cAMP biosynthetic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0001541//ovarian follicle development;GO:0032611//interleukin-1 beta production;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0016567//protein ubiquitination;GO:0006198//cAMP catabolic process;GO:0019233//sensory perception of pain;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0043410//positive regulation of MAPK cascade;GO:0001963//synaptic transmission, dopaminergic;GO:0001934//positive regulation of protein phosphorylation;GO:0006935//chemotaxis;GO:0008344//adult locomotory behavior;GO:0001911;GO:0045184//establishment of protein localization;GO:0007417//central nervous system development;GO:0002090//regulation of receptor internalization;GO:0002224//toll-like receptor signaling pathway;GO:0043087//regulation of GTPase activity;GO:0001818//negative regulation of cytokine production;GO:0006816//calcium ion transport;GO:0006171//cAMP biosynthetic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010656//negative regulation of muscle cell apoptotic process" "gi|148680614|gb|EDL12561.1|/0/arrestin, beta 2, isoform CRA_a, partial [Mus musculus]" 68760 4298.6 36.21 31.31333333 -0.209611084 Down 0.421123397 Synpo2l synaptopodin 2-like K19867|1|4e-08|63.9|cqu:CpipJ_CPIJ012054|LIM domain-binding protein 3;K18625|2|4e-08|63.9|mze:101478252|protein Shroom GO:0031674//I band;GO:0043231//intracellular membrane-bounded organelle;GO:0031674//I band;GO:0043231//intracellular membrane-bounded organelle;GO:0031674//I band;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - "gi|148669553|gb|EDL01500.1|/0/synaptopodin 2-like, partial [Mus musculus]" 407824 2188 0.976666667 0.443333333 -1.139474419 Down 0.420982361 BC020402 cDNA sequence BC020402 - - - - - 214601 2028 2.946666667 2.076666667 -0.504814206 Down 0.420954154 Slc10a3 "solute carrier family 10 (sodium/bile acid cotransporter family), member 3" "K14343|1|0.0|731|mmu:214601|solute carrier family 10 (sodium/bile acid cotransporter), member 3/5" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005343//organic acid:sodium symporter activity;GO:0005343//organic acid:sodium symporter activity GO:0030001//metal ion transport;GO:0033993//response to lipid;GO:0030001//metal ion transport;GO:0033993//response to lipid gi|880968159|ref|XP_012981319.1|/0/PREDICTED: P3 protein [Mesocricetus auratus] 21676 9491.04 14.33333333 12.07333333 -0.247550114 Down 0.420925947 Tead1 TEA domain family member 1 K09448|1|0.0|817|chx:102170445|transcriptional enhancer factor - - - gi|564330473|ref|XP_006230116.1|/0/PREDICTED: transcriptional enhancer factor TEF-1 isoform X3 [Rattus norvegicus] 381379 2075 12.10333333 14.36 0.24665132 Up 0.420925947 Med19 mediator complex subunit 19 K15137|1|1e-84|316|rno:311165|mediator of RNA polymerase II transcription subunit 19 GO:0043234//protein complex GO:0005488//binding "GO:0006351//transcription, DNA-templated" gi|157820077|ref|NP_001101211.1|/1.25304e-83/mediator of RNA polymerase II transcription subunit 19 [Rattus norvegicus] 66294 1900 12.15666667 14.41666667 0.245989933 Up 0.420925947 Fam3a "family with sequence similarity 3, member A" "K07747|1|5e-34|148|aam:106494905|beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:3.4.23.45];K09666|2|3e-25|119|hro:HELRODRAFT_188882|beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.-]" - - - - 381792 710.94 9.133333333 11 0.268290131 Up 0.420916544 2310040G24Rik RIKEN cDNA 2310040G24 gene - - - - - 100134861 4547 21.84 25.48 0.222392421 Up 0.420672082 ChkbCpt1b "predicted readthrough transcript (NMD candidate), 44502" "K19523|1|0.0|931|mmu:12895|carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]" - - - - 69120 654 1.57 2.343333333 0.577797629 Up 0.420606266 1810021B22Rik RIKEN cDNA 1810021B22 gene - - - - - 277010 3077 17.77333333 20.80666667 0.227331577 Up 0.420596863 Marveld1 MARVEL (membrane-associating) domain containing 1 - - - - - 212163 3418 4.41 3.353333333 -0.395182756 Down 0.420587461 8030462N17Rik RIKEN cDNA 8030462N17 gene K10635|1|4e-15|86.7|hgl:101696783|E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27] - - - gi|87196345|ref|NP_848785.2|/0/uncharacterized protein C18orf25 homolog [Mus musculus] 71885 3175 4.51 5.73 0.345407706 Up 0.420455828 Faap100 Fanconi anemia core complex associated protein 100 K10993|1|0.0|1780|mmu:71885|fanconi anemia core complex 100 kDa subunit GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress "gi|148702794|gb|EDL34741.1|/0/RIKEN cDNA 2310003H01, isoform CRA_b, partial [Mus musculus]" 16706 4087 3.62 2.66 -0.444563452 Down 0.420117342 Ksr1 kinase suppressor of ras 1 K14958|1|0.0|1543|mmu:16706|kinase suppressor of Ras 1 GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity;GO:0032947//protein complex scaffold;GO:0019901//protein kinase binding GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0000165//MAPK cascade gi|7305215|ref|NP_038599.1|/0/kinase suppressor of Ras 1 [Mus musculus] 11666 3664 22.34 25.95333333 0.216290658 Up 0.420089135 Abcd1 "ATP-binding cassette, sub-family D (ALD), member 1" "K05675|1|0.0|1369|mmu:11666|ATP-binding cassette, subfamily D (ALD), member 1" GO:0031231//intrinsic component of peroxisomal membrane GO:0032550;GO:0005324//long-chain fatty acid transporter activity;GO:0017111//nucleoside-triphosphatase activity;GO:0042802//identical protein binding GO:0000038//very long-chain fatty acid metabolic process;GO:0015909//long-chain fatty acid transport;GO:0001676//long-chain fatty acid metabolic process;GO:0009062//fatty acid catabolic process;GO:0006996//organelle organization;GO:0009154//purine ribonucleotide catabolic process gi|6671497|ref|NP_031461.1|/0/ATP-binding cassette sub-family D member 1 [Mus musculus] 78286 11126.82 10.96666667 9.113333333 -0.267074341 Down 0.420060927 Nav2 neuron navigator 2 K19483|1|0.0|3858|rno:171563|neuron navigator 2 [EC:3.6.4.12] - - - gi|167466226|ref|NP_001104486.1|/0/neuron navigator 2 isoform 2 [Mus musculus] 72440 1633.35 6.04 7.49 0.310417169 Up 0.419966904 Rhno1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 - GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle - GO:0045023//G0 to G1 transition;GO:0010212//response to ionizing radiation;GO:0009411//response to UV;GO:0006281//DNA repair;GO:0045023//G0 to G1 transition;GO:0010212//response to ionizing radiation;GO:0009411//response to UV;GO:0006281//DNA repair gi|74222291|dbj|BAE26947.1|/1.13808e-125/unnamed protein product [Mus musculus] 14239 1311 4.743333333 3.633333333 -0.384607527 Down 0.419929294 Foxs1 forkhead box S1 K09412|1|4e-176|619|mmu:14239|forkhead-like 18 protein - - - "gi|148674052|gb|EDL05999.1|/0/forkhead-like 18 (Drosophila), partial [Mus musculus]" 66170 1313 7.876666667 9.593333333 0.284446963 Up 0.419825868 Chchd5 coiled-coil-helix-coiled-coil-helix domain containing 5 - - - - "gi|148696281|gb|EDL28228.1|/4.43378e-75/coiled-coil-helix-coiled-coil-helix domain containing 5, partial [Mus musculus]" 12409 1021 34.07333333 29.36666667 -0.214463572 Down 0.419807063 Cbr2 carbonyl reductase 2 K00081|1|6e-132|472|mmu:12409|carbonyl reductase 2 [EC:1.1.1.184] GO:0042995//cell projection;GO:0044429 "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0005515//protein binding;GO:0036094//small molecule binding;GO:0016651//oxidoreductase activity, acting on NAD(P)H" GO:0055114//oxidation-reduction process;GO:0019318//hexose metabolic process;GO:0051260//protein homooligomerization;GO:0019321;GO:0046496//nicotinamide nucleotide metabolic process gi|6671688|ref|NP_031647.1|/5.08658e-131/carbonyl reductase [NADPH] 2 [Mus musculus] 52838 2928.95 21.92333333 25.51 0.218595729 Up 0.419722442 Dnlz DNL-type zinc finger K17808|1|6e-64|248|mmu:52838|mitochondrial protein import protein ZIM17 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0046872//metal ion binding - gi|218777849|ref|NP_001132975.1|/2.22437e-17/DNL-type zinc finger protein isoform 2 [Mus musculus] 68936 517 47.13 54.25666667 0.203154735 Up 0.419628418 Smim11 small integral membrane protein 11 K10807|1|3e-10|66.6|ccw:104698094|ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] GO:0031224//intrinsic component of membrane - - gi|20270271|ref|NP_620082.1|/1.41368e-22/small integral membrane protein 11A [Mus musculus] 101142 2314 5.133333333 6.443333333 0.327911287 Up 0.419562601 Itfg2 integrin alpha FG-GAP repeat containing 2 - - - - gi|19527142|ref|NP_598688.1|/0/integrin-alpha FG-GAP repeat-containing protein 2 [Mus musculus] 53872 4531.11 33.68666667 29.02666667 -0.214798772 Down 0.419524992 Caprin1 cell cycle associated protein 1 K18743|1|0.0|1030|mmu:53872|caprin-1 GO:0043005//neuron projection;GO:0035770//ribonucleoprotein granule;GO:0044444//cytoplasmic part;GO:0043005//neuron projection;GO:0035770//ribonucleoprotein granule;GO:0044444//cytoplasmic part;GO:0043005//neuron projection;GO:0035770//ribonucleoprotein granule;GO:0044444//cytoplasmic part;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0035770//ribonucleoprotein granule;GO:0044444//cytoplasmic part;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0035770//ribonucleoprotein granule;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0006412//translation;GO:0048869//cellular developmental process;GO:0031346//positive regulation of cell projection organization;GO:0006412//translation;GO:0048869//cellular developmental process;GO:0031346//positive regulation of cell projection organization;GO:0006412//translation;GO:0048869//cellular developmental process;GO:0031346//positive regulation of cell projection organization;GO:0006412//translation;GO:0031346//positive regulation of cell projection organization;GO:0048869//cellular developmental process;GO:0006412//translation;GO:0031346//positive regulation of cell projection organization;GO:0048869//cellular developmental process "gi|148695758|gb|EDL27705.1|/0/GPI-anchored membrane protein 1, isoform CRA_a, partial [Mus musculus]" 320924 5742 1.333333333 0.726666667 -0.875671865 Down 0.419402761 Ccbe1 collagen and calcium binding EGF domains 1 K19638|1|0.0|647|mmu:320924|collagen and calcium-binding EGF domain-containing protein 1 - - - - 54199 2077.46 11.63 13.83666667 0.250645334 Up 0.419318139 Ccrl2 chemokine (C-C motif) receptor-like 2 K08373|1|0.0|666|mmu:54199|C-C chemokine receptor-like 2 GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0042379//chemokine receptor binding;GO:0004950//chemokine receptor activity;GO:0042379//chemokine receptor binding;GO:0004950//chemokine receptor activity;GO:0042379//chemokine receptor binding;GO:0004950//chemokine receptor activity GO:0019221//cytokine-mediated signaling pathway;GO:0006952//defense response;GO:0019221//cytokine-mediated signaling pathway;GO:0006952//defense response;GO:0019221//cytokine-mediated signaling pathway;GO:0006952//defense response "gi|148677032|gb|EDL08979.1|/0/chemokine (C-C motif) receptor-like 2, isoform CRA_a, partial [Mus musculus]" 74318 1208.49 130.33 148.2466667 0.185830457 Up 0.419214713 Hopx HOP homeobox - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0030324//lung development;GO:0006476//protein deacetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0044057;GO:0051146//striated muscle cell differentiation;GO:0043403//skeletal muscle tissue regeneration;GO:0051098//regulation of binding;GO:0001825//blastocyst formation;GO:0030324//lung development;GO:0006476//protein deacetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0044057;GO:0051146//striated muscle cell differentiation;GO:0043403//skeletal muscle tissue regeneration;GO:0051098//regulation of binding;GO:0001825//blastocyst formation;GO:0030324//lung development;GO:0006476//protein deacetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0044057;GO:0051146//striated muscle cell differentiation;GO:0043403//skeletal muscle tissue regeneration;GO:0051098//regulation of binding;GO:0001825//blastocyst formation gi|28269685|ref|NP_783199.1|/5.9274e-35/homeodomain-only protein [Mus musculus] 16970 2208.04 0.533333333 1.08 1.017921908 Up 0.419167701 Lrmp lymphoid-restricted membrane protein "K12337|1|9e-29|131|crg:105334848|inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate" GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane - - gi|162287383|ref|NP_032537.3|/0/lymphoid-restricted membrane protein isoform 1 [Mus musculus] 22210 2141 121.8733333 139.4133333 0.193986056 Up 0.419017263 Ube2b ubiquitin-conjugating enzyme E2B K10574|1|1e-88|330|rno:103694902|ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23] GO:0000803//sex chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0000151//ubiquitin ligase complex;GO:0000785//chromatin;GO:0016020//membrane GO:0019787//ubiquitin-like protein transferase activity;GO:0032550;GO:0044389//ubiquitin-like protein ligase binding GO:0032868//response to insulin;GO:0006915//apoptotic process;GO:0016055//Wnt signaling pathway;GO:0006281//DNA repair;GO:0003006//developmental process involved in reproduction;GO:0043009//chordate embryonic development;GO:0048232//male gamete generation;GO:0007129//synapsis;GO:0001933//negative regulation of protein phosphorylation;GO:0009416//response to light stimulus;GO:0016577//histone demethylation;GO:0009968//negative regulation of signal transduction;GO:0007131//reciprocal meiotic recombination;GO:0016574//histone ubiquitination;GO:0000209//protein polyubiquitination;GO:0031647//regulation of protein stability;GO:0006511//ubiquitin-dependent protein catabolic process "gi|149052521|gb|EDM04338.1|/8.68658e-88/ubiquitin-conjugating enzyme E2B, RAD6 homolog (S. cerevisiae), isoform CRA_a [Rattus norvegicus]" 100217418 117 0.593333333 1.176666667 0.987790942 Up 0.418989056 Snora44 "small nucleolar RNA, H/ACA box 44" - - - - - 15354 1672.17 45.72 52.64 0.203334086 Up 0.418951446 Hmgb3 high mobility group box 3 K11296|1|1e-90|318|rno:100912369|high mobility group protein B3 GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0043566//structure-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0043566//structure-specific DNA binding GO:0006259//DNA metabolic process;GO:0030099//myeloid cell differentiation;GO:0030183//B cell differentiation;GO:0006259//DNA metabolic process;GO:0030099//myeloid cell differentiation;GO:0030183//B cell differentiation;GO:0006259//DNA metabolic process;GO:0030099//myeloid cell differentiation;GO:0030183//B cell differentiation;GO:0006259//DNA metabolic process;GO:0030099//myeloid cell differentiation;GO:0030183//B cell differentiation "gi|148694630|gb|EDL26577.1|/3.99688e-90/mCG10155, isoform CRA_d, partial [Mus musculus]" 58222 2193 0.493333333 1.03 1.062009662 Up 0.418895032 Rab37 "RAB37, member RAS oncogene family" K07914|1|1e-113|413|ecb:100052585|Ras-related protein Rab-37;K13365|3|4e-112|408|chx:102177376|Na(+)/H(+) exchange regulatory cofactor NHE-RF1 "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0045184//establishment of protein localization;GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0045184//establishment of protein localization gi|254939625|ref|NP_067386.3|/2.34267e-112/ras-related protein Rab-37 isoform 1 [Mus musculus] 232223 2836 7.196666667 8.79 0.288534328 Up 0.41884802 Txnrd3 thioredoxin reductase 3 K00384|1|1e-142|509|mmu:232223|thioredoxin reductase (NADPH) [EC:1.8.1.9] GO:0043231//intracellular membrane-bounded organelle "GO:0000166//nucleotide binding;GO:0015036//disulfide oxidoreductase activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H" GO:0048869//cellular developmental process;GO:0044710;GO:0006790//sulfur compound metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0019725//cellular homeostasis;GO:0048232//male gamete generation;GO:0051234//establishment of localization gi|74149124|dbj|BAE22370.1|/0/unnamed protein product [Mus musculus] 18207 1080 2.726666667 1.9 -0.521138924 Down 0.418838617 Nthl1 nth (endonuclease III)-like 1 (E.coli) K10773|1|1e-145|518|mmu:18207|endonuclease III [EC:4.2.99.18] GO:0043231//intracellular membrane-bounded organelle "GO:0016835//carbon-oxygen lyase activity;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0004518//nuclease activity;GO:0043566//structure-specific DNA binding" "GO:0033683//nucleotide-excision repair, DNA incision;GO:0006284//base-excision repair" gi|227908769|ref|NP_032769.2|/1.14859e-144/endonuclease III-like protein 1 [Mus musculus] 21815 1574.5 2.67 3.623333333 0.440477793 Up 0.418819813 Tgif1 TGFB-induced factor homeobox 1 K19383|1|5e-119|430|mmu:21815|homeobox protein TGIF1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0019901//protein kinase binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046332//SMAD binding;GO:0019901//protein kinase binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046332//SMAD binding;GO:0019901//protein kinase binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046332//SMAD binding;GO:0019901//protein kinase binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046332//SMAD binding;GO:0019901//protein kinase binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046332//SMAD binding GO:0070848//response to growth factor;GO:0014020;GO:0007369//gastrulation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043010//camera-type eye development;GO:0009968//negative regulation of signal transduction;GO:0009855//determination of bilateral symmetry;GO:0003002//regionalization;GO:0008284//positive regulation of cell proliferation;GO:0032924//activin receptor signaling pathway;GO:0030182//neuron differentiation;GO:0070848//response to growth factor;GO:0014020;GO:0007369//gastrulation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043010//camera-type eye development;GO:0009968//negative regulation of signal transduction;GO:0009855//determination of bilateral symmetry;GO:0003002//regionalization;GO:0008284//positive regulation of cell proliferation;GO:0032924//activin receptor signaling pathway;GO:0030182//neuron differentiation;GO:0070848//response to growth factor;GO:0014020;GO:0007369//gastrulation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043010//camera-type eye development;GO:0009968//negative regulation of signal transduction;GO:0009855//determination of bilateral symmetry;GO:0003002//regionalization;GO:0008284//positive regulation of cell proliferation;GO:0032924//activin receptor signaling pathway;GO:0030182//neuron differentiation;GO:0070848//response to growth factor;GO:0014020;GO:0007369//gastrulation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043010//camera-type eye development;GO:0009968//negative regulation of signal transduction;GO:0009855//determination of bilateral symmetry;GO:0003002//regionalization;GO:0008284//positive regulation of cell proliferation;GO:0032924//activin receptor signaling pathway;GO:0030182//neuron differentiation;GO:0070848//response to growth factor;GO:0014020;GO:0007369//gastrulation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043010//camera-type eye development;GO:0009968//negative regulation of signal transduction;GO:0009855//determination of bilateral symmetry;GO:0003002//regionalization;GO:0008284//positive regulation of cell proliferation;GO:0032924//activin receptor signaling pathway;GO:0030182//neuron differentiation "gi|148706416|gb|EDL38363.1|/3.47761e-118/TG interacting factor, isoform CRA_a [Mus musculus]" 56401 2988.91 6.57 8.073333333 0.297271089 Up 0.418791606 P3h1 prolyl 3-hydroxylase 1 K08134|1|0.0|1318|mmu:56401|leucine proline-enriched proteoglycan (leprecan) GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix "GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798//procollagen-proline dioxygenase activity;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798//procollagen-proline dioxygenase activity;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798//procollagen-proline dioxygenase activity;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798//procollagen-proline dioxygenase activity;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0001503//ossification;GO:0040007//growth;GO:0030198//extracellular matrix organization;GO:0001503//ossification;GO:0040007//growth;GO:0030198//extracellular matrix organization;GO:0001503//ossification;GO:0040007//growth;GO:0030198//extracellular matrix organization;GO:0001503//ossification;GO:0040007//growth;GO:0030198//extracellular matrix organization gi|109150433|ref|NP_062757.2|/0/prolyl 3-hydroxylase 1 isoform 2 precursor [Mus musculus] 19285 3218 136.2566667 119.61 -0.187988808 Down 0.41861296 Ptrf polymerase I and transcript release factor K19387|1|0.0|671|mmu:19285|polymerase I and transcript release factor - - - - 268445 3336 8.766666667 10.58666667 0.272148113 Up 0.418584753 Ankrd13b ankyrin repeat domain 13b K05766|1|0.0|687|ssc:100515297|protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48];K16943|2|3e-158|562|tca:655956|septin 4;K00910|3|4e-50|202|apla:101801089|beta-adrenergic-receptor kinase [EC:2.7.11.15] - - - gi|117956383|ref|NP_766533.2|/0/ankyrin repeat domain-containing protein 13B [Mus musculus] 100316778 74 2.52 3.446666667 0.451778046 Up 0.418565948 Mir1982 microRNA 1982 - - - - - 71720 6719.06 4.333333333 5.53 0.351802263 Up 0.418547144 Osbpl3 oxysterol binding protein-like 3 K20463|1|0.0|1545|mmu:71720|oxysterol-binding protein-related protein 3/6/7 GO:0044432;GO:0005635//nuclear envelope;GO:0016020//membrane;GO:0044432;GO:0005635//nuclear envelope;GO:0016020//membrane GO:0032934//sterol binding;GO:0032934//sterol binding GO:0010876//lipid localization;GO:0010876//lipid localization;GO:0051234//establishment of localization "gi|148666204|gb|EDK98620.1|/0/oxysterol binding protein-like 3, isoform CRA_b, partial [Mus musculus]" 110213 2400.92 114.28 130.4866667 0.191329456 Up 0.418349693 Tmbim6 transmembrane BAX inhibitor motif containing 6 - GO:0044425;GO:0044425;GO:0044425;GO:0044425 - GO:0030323//respiratory tube development;GO:0034976//response to endoplasmic reticulum stress;GO:0006915//apoptotic process;GO:0006874//cellular calcium ion homeostasis;GO:0048232//male gamete generation;GO:0030323//respiratory tube development;GO:0034976//response to endoplasmic reticulum stress;GO:0006915//apoptotic process;GO:0006874//cellular calcium ion homeostasis;GO:0048232//male gamete generation;GO:0030323//respiratory tube development;GO:0034976//response to endoplasmic reticulum stress;GO:0006915//apoptotic process;GO:0006874//cellular calcium ion homeostasis;GO:0048232//male gamete generation;GO:0030323//respiratory tube development;GO:0034976//response to endoplasmic reticulum stress;GO:0006915//apoptotic process;GO:0006874//cellular calcium ion homeostasis;GO:0048232//male gamete generation "gi|148672185|gb|EDL04132.1|/1.61511e-93/testis enhanced gene transcript, isoform CRA_a, partial [Mus musculus]" 11565 1806 129.5233333 113.3 -0.193064158 Down 0.418349693 Adssl1 adenylosuccinate synthetase like 1 K01939|1|0.0|899|mmu:11565|adenylosuccinate synthase [EC:6.3.4.4] - - - - 20649 2153 0.803333333 0.313333333 -1.358300485 Down 0.418340291 Sntb1 "syntrophin, basic 1" K12196|1|8e-124|447|pps:100979126|vacuolar protein-sorting-associated protein 4;K00431|2|2e-16|90.5|ola:101156451|thyroid peroxidase [EC:1.11.1.8];K14548|3|7e-10|68.6|tgu:100229140|U3 small nucleolar RNA-associated protein 4;K12076|4|3e-07|60.1|xma:102229442|disks large protein 1;K06092|5|8e-07|58.5|hgl:101719449|InaD-like protein GO:0043234//protein complex;GO:0005886//plasma membrane;GO:0043232 GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding GO:0003012//muscle system process gi|7710096|ref|NP_057876.1|/0/beta-1-syntrophin [Mus musculus] 117149 4714.01 2.456666667 3.37 0.456046473 Up 0.418321486 Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein K05403|1|3e-102|376|mmu:117149|toll-interleukin 1 receptor (TIR) domain-containing adaptor protein "GO:0042579//microbody;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0001726//ruffle;GO:0042579//microbody;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0001726//ruffle;GO:0042579//microbody;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0001726//ruffle;GO:0042579//microbody;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0001726//ruffle" GO:0042802//identical protein binding;GO:0035325//Toll-like receptor binding;GO:0019901//protein kinase binding;GO:0046983//protein dimerization activity;GO:0043168//anion binding;GO:0042802//identical protein binding;GO:0035325//Toll-like receptor binding;GO:0019901//protein kinase binding;GO:0046983//protein dimerization activity;GO:0043168//anion binding;GO:0042802//identical protein binding;GO:0035325//Toll-like receptor binding;GO:0019901//protein kinase binding;GO:0046983//protein dimerization activity;GO:0043168//anion binding;GO:0042802//identical protein binding;GO:0035325//Toll-like receptor binding;GO:0019901//protein kinase binding;GO:0046983//protein dimerization activity;GO:0043168//anion binding GO:0042108//positive regulation of cytokine biosynthetic process;GO:0030097//hemopoiesis;GO:0070339;GO:0032092//positive regulation of protein binding;GO:0034142//toll-like receptor 4 signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032479//regulation of type I interferon production;GO:0019221//cytokine-mediated signaling pathway;GO:0042742//defense response to bacterium;GO:0007254//JNK cascade;GO:0070391;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0032722//positive regulation of chemokine production;GO:0030888//regulation of B cell proliferation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0044126;GO:0000187//activation of MAPK activity;GO:0048255//mRNA stabilization;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0030097//hemopoiesis;GO:0070339;GO:0032092//positive regulation of protein binding;GO:0034142//toll-like receptor 4 signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032479//regulation of type I interferon production;GO:0019221//cytokine-mediated signaling pathway;GO:0042742//defense response to bacterium;GO:0007254//JNK cascade;GO:0070391;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0032722//positive regulation of chemokine production;GO:0030888//regulation of B cell proliferation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0044126;GO:0000187//activation of MAPK activity;GO:0048255//mRNA stabilization;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0030097//hemopoiesis;GO:0070339;GO:0032092//positive regulation of protein binding;GO:0034142//toll-like receptor 4 signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032479//regulation of type I interferon production;GO:0019221//cytokine-mediated signaling pathway;GO:0042742//defense response to bacterium;GO:0007254//JNK cascade;GO:0070391;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0032722//positive regulation of chemokine production;GO:0030888//regulation of B cell proliferation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0044126;GO:0000187//activation of MAPK activity;GO:0048255//mRNA stabilization;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0030097//hemopoiesis;GO:0070339;GO:0032092//positive regulation of protein binding;GO:0034142//toll-like receptor 4 signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032479//regulation of type I interferon production;GO:0019221//cytokine-mediated signaling pathway;GO:0042742//defense response to bacterium;GO:0007254//JNK cascade;GO:0070391;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0032722//positive regulation of chemokine production;GO:0030888//regulation of B cell proliferation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0044126;GO:0000187//activation of MAPK activity;GO:0048255//mRNA stabilization "gi|148693432|gb|EDL25379.1|/5.44195e-115/toll-interleukin 1 receptor (TIR) domain-containing adaptor protein, isoform CRA_b, partial [Mus musculus]" 72333 5300.75 53.11666667 46.38333333 -0.19555811 Down 0.418293279 Palld "palladin, cytoskeletal associated protein" K19875|1|1e-76|291|lcm:102367192|myotilin GO:0005924//cell-substrate adherens junction;GO:0031252//cell leading edge;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0031674//I band GO:0051393//alpha-actinin binding GO:0006996//organelle organization "gi|50370130|gb|AAH76588.1|/0/Palld protein, partial [Mus musculus]" 228911 5139 8.596666667 7.013333333 -0.293677068 Down 0.418246267 Tshz2 teashirt zinc finger family member 2 K09236|1|0.0|1868|mmu:228911|teashirt GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|60360646|dbj|BAD90333.1|/0/mKIAA4248 protein [Mus musculus] 54399 1552 4.596666667 5.836666667 0.344556627 Up 0.418199255 Bet1l Bet1 golgi vesicular membrane trafficking protein like K08504|1|3e-64|230|cge:100770224|blocked early in transport 1 - - - - 100041230 405 0.01 0.303333333 4.922832139 Up 0.418152243 Hist1h4m "histone cluster 1, H4m" K11254|1|2e-41|169|ecb:100068166|histone H4;K11253|2|4e-40|164|bacu:103011346|histone H3 - - - gi|953881761|ref|XP_014590042.1|/2.08031e-40/PREDICTED: histone H4 [Equus caballus] 68243 819 0.303333333 0.01 -4.922832139 Down 0.418152243 A930018P22Rik RIKEN cDNA A930018P22 gene - - - - gi|13386126|ref|NP_080910.1|/1.16804e-62/uncharacterized protein C11orf91 homolog [Mus musculus] 16709 4480.63 24.15333333 20.68666667 -0.223521109 Down 0.418124036 Ktn1 kinectin 1 K17975|1|0.0|1992|mmu:16709|kinectin GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0006928//movement of cell or subcellular component;GO:0006928//movement of cell or subcellular component;GO:0006928//movement of cell or subcellular component gi|144922638|ref|NP_032503.2|/0/kinectin isoform 1 [Mus musculus] 56316 3323 7.81 9.5 0.282604965 Up 0.418105231 Ggcx gamma-glutamyl carboxylase K10106|1|0.0|1369|mmu:56316|vitamin K-dependent gamma-carboxylase [EC:4.1.1.90] GO:0043227//membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0033218//amide binding;GO:0036094//small molecule binding;GO:0016831//carboxy-lyase activity GO:0007275//multicellular organism development;GO:0033273//response to vitamin;GO:0018200//peptidyl-glutamic acid modification gi|9790009|ref|NP_062776.1|/0/vitamin K-dependent gamma-carboxylase [Mus musculus] 102132 1856 9.59 7.9 -0.279678162 Down 0.418105231 E230013L22Rik RIKEN cDNA E230013L22 gene K07911|1|4e-25|119|oas:101116740|Ras-related protein Rab-20 - - - - 381633 569 0.616666667 1.2 0.960471636 Up 0.417973598 Gm1673 predicted gene 1673 - - - - "gi|148705492|gb|EDL37439.1|/2.1188e-29/mCG16345, isoform CRA_a, partial [Mus musculus]" 16874 3355.7 6.246666667 4.96 -0.332746427 Down 0.417917184 Lhx6 LIM homeobox protein 6 K09375|1|0.0|752|cge:100769913|LIM homeobox protein 6/8 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0021879//forebrain neuron differentiation;GO:0021795//cerebral cortex cell migration;GO:0006351//transcription, DNA-templated;GO:0021700//developmental maturation;GO:0021830//interneuron migration from the subpallium to the cortex;GO:0021879//forebrain neuron differentiation;GO:0021795//cerebral cortex cell migration;GO:0006351//transcription, DNA-templated;GO:0021700//developmental maturation;GO:0021830//interneuron migration from the subpallium to the cortex" gi|133893073|ref|NP_001076594.1|/0/LIM/homeobox protein Lhx6 isoform 2 [Mus musculus] 677044 1232 5.916666667 7.333333333 0.309684499 Up 0.417860769 Gm10653 ribsomal protein S2 pseudogene K02981|1|2e-111|347|ggo:101151037|small subunit ribosomal protein S2e - - - - 19769 2514.53 20.76666667 24.21333333 0.221532039 Up 0.417832562 Rit1 Ras-like without CAAX 1 K07832|1|4e-110|370|mmu:19769|Ras-like without CAAX 1 GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|755503497|ref|XP_011238346.1|/3.34875e-139/PREDICTED: GTP-binding protein Rit1 isoform X3 [Mus musculus] 68066 1678 108.26 123.58 0.190944985 Up 0.417776148 Slc25a39 "solute carrier family 25, member 39" "K15119|1|0.0|719|mmu:68066|solute carrier family 25, member 39/40" GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0006779//porphyrin-containing compound biosynthetic process gi|13386046|ref|NP_080818.1|/0/solute carrier family 25 member 39 [Mus musculus] 57170 2268 3.633333333 4.72 0.37749313 Up 0.417776148 Dolpp1 dolichyl pyrophosphate phosphatase 1 K07252|1|5e-102|374|ngi:103727910|dolichyldiphosphatase [EC:3.6.1.43] GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0016462//pyrophosphatase activity;GO:0016462//pyrophosphatase activity;GO:0016462//pyrophosphatase activity;GO:0016462//pyrophosphatase activity GO:0006486//protein glycosylation;GO:0006486//protein glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0006487//protein N-linked glycosylation;GO:0006486//protein glycosylation gi|674038212|ref|XP_008824238.1|/4.0164e-101/PREDICTED: dolichyldiphosphatase 1 isoform X1 [Nannospalax galili] 12502 1023 0.056666667 0.426666667 2.912537159 Up 0.417672722 Cd3g "CD3 antigen, gamma polypeptide" K06452|1|3e-100|367|mmu:12502|T-cell surface glycoprotein CD3 gamma chain GO:0042101//T cell receptor complex;GO:0031224//intrinsic component of membrane GO:0046983//protein dimerization activity;GO:0038023//signaling receptor activity GO:0045184//establishment of protein localization;GO:0007165//signal transduction;GO:0006915//apoptotic process gi|6753350|ref|NP_033980.1|/2.31618e-99/T-cell surface glycoprotein CD3 gamma chain precursor [Mus musculus] 243771 3322 8.78 10.57666667 0.268592176 Up 0.417578698 Parp12 "poly (ADP-ribose) polymerase family, member 12" K15259|1|0.0|1353|mmu:243771|poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30] GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0016763//transferase activity, transferring pentosyl groups" - gi|171543897|ref|NP_766481.2|/0/poly [ADP-ribose] polymerase 12 [Mus musculus] 17304 2052.84 106.2166667 121.18 0.190141451 Up 0.417541088 Mfge8 milk fat globule-EGF factor 8 protein K17253|1|0.0|931|mmu:17304|lactadherin GO:0031988//membrane-bounded vesicle;GO:0019898//extrinsic component of membrane;GO:0009986//cell surface;GO:0044421;GO:0031988//membrane-bounded vesicle;GO:0019898//extrinsic component of membrane;GO:0009986//cell surface;GO:0044421 GO:0005543//phospholipid binding;GO:0005102//receptor binding;GO:0005543//phospholipid binding;GO:0005102//receptor binding GO:0022610;GO:0048545//response to steroid hormone;GO:0009566//fertilization;GO:0008283//cell proliferation;GO:0043277//apoptotic cell clearance;GO:0022610;GO:0048545//response to steroid hormone;GO:0009566//fertilization;GO:0008283//cell proliferation;GO:0043277//apoptotic cell clearance gi|113865979|ref|NP_032620.2|/0/lactadherin isoform 1 precursor [Mus musculus] 50887 1911 3.393333333 4.453333333 0.392182446 Up 0.417447065 Hmgn5 high-mobility group nucleosome binding domain 5 K17045|1|5e-126|454|mmu:50887|high-mobility group nucleosome-binding domain-containing protein 5 GO:0031981//nuclear lumen GO:0005488//binding GO:0006366//transcription from RNA polymerase II promoter gi|133778915|ref|NP_057919.2|/4.52763e-125/high mobility group nucleosome-binding domain-containing protein 5 [Mus musculus] 67846 2869 3.393333333 4.45 0.39110218 Up 0.417447065 Tmem39a transmembrane protein 39a K16531|1|8e-23|112|tsp:Tsp_10250|Bardet-Biedl syndrome 4 protein GO:0031224//intrinsic component of membrane;GO:0016020//membrane;GO:0031224//intrinsic component of membrane - - gi|27754069|ref|NP_080683.2|/0/transmembrane protein 39A isoform 1 [Mus musculus] 12962 854 0.99 1.65 0.736965594 Up 0.417381248 Crybb3 "crystallin, beta B3" K16810|1|9e-24|112|bacu:103015945|TBCC domain-containing protein 1;K01886|2|7e-11|70.1|ccw:104683491|glutaminyl-tRNA synthetase [EC:6.1.1.18] - GO:0005198//structural molecule activity;GO:0005198//structural molecule activity - gi|10946674|ref|NP_067327.1|/4.89685e-116/beta-crystallin B3 [Mus musculus] 414801 3781 6.366666667 7.846666667 0.301541682 Up 0.417324834 Itprip "inositol 1,4,5-triphosphate receptor interacting protein" - GO:0016020//membrane GO:0005488//binding GO:0006915//apoptotic process gi|60359856|dbj|BAD90147.1|/0/mKIAA1754 protein [Mus musculus] 225888 4419.23 6.313333333 7.79 0.303221403 Up 0.417324834 Suv420h1 suppressor of variegation 4-20 homolog 1 (Drosophila) K11429|1|0.0|1517|mmu:225888|histone-lysine N-methyltransferase SUV420H [EC:2.1.1.43] GO:0000794//condensed nuclear chromosome;GO:0000794//condensed nuclear chromosome;GO:0000794//condensed nuclear chromosome;GO:0000794//condensed nuclear chromosome;GO:0000794//condensed nuclear chromosome;GO:0000794//condensed nuclear chromosome;GO:0000794//condensed nuclear chromosome GO:0018024//histone-lysine N-methyltransferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0018024//histone-lysine N-methyltransferase activity "GO:0034968//histone lysine methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0006351//transcription, DNA-templated;GO:0034968//histone lysine methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0006351//transcription, DNA-templated;GO:0034968//histone lysine methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0006351//transcription, DNA-templated;GO:0034968//histone lysine methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0006351//transcription, DNA-templated;GO:0034968//histone lysine methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0006351//transcription, DNA-templated;GO:0034968//histone lysine methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0006351//transcription, DNA-templated;GO:0034968//histone lysine methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0006351//transcription, DNA-templated" "gi|148701006|gb|EDL32953.1|/0/suppressor of variegation 4-20 homolog 1 (Drosophila), isoform CRA_b, partial [Mus musculus]" 16976 2922 28.01 32.41 0.210497037 Up 0.417268419 Lrpap1 low density lipoprotein receptor-related protein associated protein 1 - GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane GO:0070325//lipoprotein particle receptor binding;GO:0019899//enzyme binding;GO:0005539//glycosaminoglycan binding GO:0009968//negative regulation of signal transduction;GO:0043393//regulation of protein binding;GO:0010915;GO:0051241 gi|63999380|ref|NP_038615.2|/0/alpha-2-macroglobulin receptor-associated protein precursor [Mus musculus] 212090 899 11.47666667 13.62666667 0.247729015 Up 0.41723081 Tmem60 transmembrane protein 60 "K18207|1|2e-07|58.9|phu:Phum_PHUM177410|protein O-mannose beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.312]" GO:0016020//membrane - - gi|514460923|ref|XP_005003697.1|/1.13434e-48/PREDICTED: transmembrane protein 60 [Cavia porcellus] 105727 7119.54 1.343333333 2.07 0.62381343 Up 0.417212005 Slc38a1 "solute carrier family 38, member 1" "K14990|1|0.0|841|mmu:105727|solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 1" GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane GO:0008324//cation transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0006865//amino acid transport;GO:0030001//metal ion transport;GO:0006865//amino acid transport;GO:0030001//metal ion transport;GO:0006865//amino acid transport;GO:0030001//metal ion transport "gi|148672291|gb|EDL04238.1|/0/solute carrier family 38, member 1, isoform CRA_a, partial [Mus musculus]" 208748 5967.96 3.44 2.523333333 -0.447077765 Down 0.417174395 Prrg3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) K04949|1|6e-15|87.0|ocu:100009269|cyclic nucleotide gated channel alpha 2;K01320|2|1e-09|69.3|pss:102463876|coagulation factor VII [EC:3.4.21.21] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding;GO:0046872//metal ion binding - gi|124487491|ref|NP_001074604.1|/1.83353e-107/transmembrane gamma-carboxyglutamic acid protein 3 precursor [Mus musculus] 56464 1975 28.53333333 32.92 0.20631604 Up 0.417174395 Ctsf cathepsin F K01373|1|0.0|804|mmu:56464|cathepsin F [EC:3.4.22.41] - "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process gi|11066228|gb|AAG28508.1|AF197480_1/0/cathepsin F [Mus musculus] 64381 1116 0.363333333 0.866666667 1.254183488 Up 0.417146188 Ms4a8a "membrane-spanning 4-domains, subfamily A, member 8A" "K19928|1|4e-14|81.6|clv:102089886|zona pellucida sperm-binding protein 3;K06466|4|6e-06|54.3|chx:102172175|membrane-spanning 4-domains, subfamily A, member 1" GO:0031224//intrinsic component of membrane - - gi|120953177|ref|NP_071875.2|/9.32621e-129/membrane-spanning 4-domains subfamily A member 8 [Mus musculus] 19347 4972 49.42 43.00666667 -0.200534695 Down 0.417080372 Dennd5a DENN/MADD domain containing 5A K20164|1|0.0|2549|rno:308942|DENN domain-containing protein 5 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0017016//Ras GTPase binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0017016//Ras GTPase binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity - gi|39930409|ref|NP_067469.1|/0/DENN domain-containing protein 5A isoform 1 [Mus musculus] 18792 2343 2.696666667 1.876666667 -0.52300478 Down 0.417014555 Plau "plasminogen activator, urokinase" K01348|1|0.0|927|mmu:18792|urokinase plasminogen activator [EC:3.4.21.73] GO:0044464;GO:0044421 "GO:0004175//endopeptidase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0035728//response to hepatocyte growth factor;GO:0032496//response to lipopolysaccharide;GO:0014909//smooth muscle cell migration;GO:0001952//regulation of cell-matrix adhesion;GO:0007275//multicellular organism development;GO:0042246//tissue regeneration;GO:0050678//regulation of epithelial cell proliferation;GO:0030195//negative regulation of blood coagulation;GO:0071242//cellular response to ammonium ion;GO:0006796//phosphate-containing compound metabolic process;GO:0001666//response to hypoxia;GO:0009966//regulation of signal transduction;GO:0048232//male gamete generation;GO:0008219//cell death;GO:0072593//reactive oxygen species metabolic process;GO:0033554//cellular response to stress;GO:0030728//ovulation;GO:0001678//cellular glucose homeostasis;GO:0019538//protein metabolic process gi|6679377|ref|NP_032899.1|/0/urokinase-type plasminogen activator precursor [Mus musculus] 380702 7487 0.136666667 0.56 2.034765418 Up 0.416939336 Shisa6 shisa family member 6 - GO:0008328//ionotropic glutamate receptor complex - - gi|85702193|ref|NP_001030046.1|/0/protein shisa-6 homolog precursor [Mus musculus] 69596 1429.07 27.09666667 31.44666667 0.214791713 Up 0.416864117 Ap5s1 "adaptor-related protein 5 complex, sigma 1 subunit" K19024|1|2e-55|219|cge:100765217|AP-5 complex subunit sigma-1 GO:0005768//endosome;GO:0000323//lytic vacuole;GO:0030117//membrane coat;GO:0005768//endosome;GO:0000323//lytic vacuole;GO:0030117//membrane coat;GO:0005768//endosome;GO:0000323//lytic vacuole;GO:0030117//membrane coat - GO:0044765//single-organism transport;GO:0006259//DNA metabolic process;GO:0045184//establishment of protein localization;GO:0033554//cellular response to stress;GO:0044765//single-organism transport;GO:0006259//DNA metabolic process;GO:0045184//establishment of protein localization;GO:0033554//cellular response to stress;GO:0044765//single-organism transport;GO:0006259//DNA metabolic process;GO:0045184//establishment of protein localization;GO:0033554//cellular response to stress "gi|148696365|gb|EDL28312.1|/1.40896e-147/RIKEN cDNA 2310035K24, isoform CRA_b, partial [Mus musculus]" 103425 2893 28.32333333 32.66666667 0.205828184 Up 0.416741886 Ncln nicalin K03283|1|1e-07|62.0|aqu:100636004|heat shock 70kDa protein 1/8 GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen GO:0016787//hydrolase activity GO:0019538//protein metabolic process;GO:0007165//signal transduction gi|344247008|gb|EGW03112.1|/0/Nicalin [Cricetulus griseus] 59035 3231 43.53333333 49.87 0.196051712 Up 0.416694874 Carm1 coactivator-associated arginine methyltransferase 1 K05931|1|0.0|1039|rno:363026|type I protein arginine methyltransferase [EC:2.1.1.319] - - - - 76199 9315 3.27 2.373333333 -0.462375895 Down 0.416610252 Med13l mediator complex subunit 13-like K15164|1|0.0|4141|mmu:76199|mediator of RNA polymerase II transcription subunit 13 - - - gi|146134449|ref|NP_766012.3|/0/mediator of RNA polymerase II transcription subunit 13-like [Mus musculus] 27883 1529 93.24666667 106.4933333 0.191639059 Up 0.416469217 Tango2 transport and golgi organization 2 - GO:0043231//intracellular membrane-bounded organelle - - gi|255918143|ref|NP_613049.2|/1.77409e-158/transport and Golgi organization 2 homolog [Mus musculus] 272396 3194 15.45 13.05666667 -0.242820211 Down 0.416450412 Tarsl2 threonyl-tRNA synthetase-like 2 K01868|1|0.0|1587|mmu:272396|threonyl-tRNA synthetase [EC:6.1.1.3] GO:0044424 GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550 GO:0006418//tRNA aminoacylation for protein translation "gi|227908819|ref|NP_758514.2|/0/probable threonine--tRNA ligase 2, cytoplasmic [Mus musculus]" 22139 1237 0.523333333 1.063333333 1.022791865 Up 0.416346986 Ttr transthyretin K07127|1|7e-17|90.9|spu:589020|5-hydroxyisourate hydrolase [EC:3.5.2.17] GO:0044421;GO:0032991//macromolecular complex GO:0046983//protein dimerization activity;GO:0005102//receptor binding GO:0051234//establishment of localization;GO:0001523//retinoid metabolic process;GO:0006575//cellular modified amino acid metabolic process gi|7305599|ref|NP_038725.1|/6.72572e-78/transthyretin precursor [Mus musculus] 72461 2964 3.436666667 4.49 0.385705518 Up 0.416262364 Prcp prolylcarboxypeptidase (angiotensinase C) K01285|1|0.0|958|mmu:72461|lysosomal Pro-X carboxypeptidase [EC:3.4.16.2] GO:0000323//lytic vacuole GO:0008238//exopeptidase activity GO:0019538//protein metabolic process gi|33469015|ref|NP_082519.1|/0/lysosomal Pro-X carboxypeptidase precursor [Mus musculus] 52713 1078 11.68 9.773333333 -0.257117671 Down 0.416243559 Ccdc59 coiled-coil domain containing 59 - GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated" gi|13385058|ref|NP_079878.1|/2.84223e-111/thyroid transcription factor 1-associated protein 26 [Mus musculus] 381356 1660.28 15.81333333 18.59666667 0.233902542 Up 0.416111926 Cacfd1 calcium channel flower domain containing 1 - GO:0031224//intrinsic component of membrane;GO:0030672//synaptic vesicle membrane;GO:0031224//intrinsic component of membrane;GO:0030672//synaptic vesicle membrane;GO:0031224//intrinsic component of membrane;GO:0030672//synaptic vesicle membrane GO:0005261//cation channel activity;GO:0005261//cation channel activity;GO:0005261//cation channel activity GO:0006897//endocytosis;GO:0006897//endocytosis;GO:0006897//endocytosis gi|342672093|ref|NP_001230168.1|/4.83356e-49/calcium channel flower homolog isoform 2 [Mus musculus] 56857 4383 1.773333333 1.096666667 -0.693338662 Down 0.415933281 Slc37a2 "solute carrier family 37 (glycerol-3-phosphate transporter), member 2" "K13783|1|0.0|938|mmu:56857|MFS transporter, OPA family, solute carrier family 37 (glycerol-3-phosphate transporter), member 1/2" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0044765//single-organism transport;GO:0044765//single-organism transport "gi|148693472|gb|EDL25419.1|/0/solute carrier family 37 (glycerol-3-phosphate transporter), member 2, isoform CRA_a, partial [Mus musculus]" 18763 14170 7.896666667 6.433333333 -0.295677351 Down 0.415933281 Pkd1 polycystic kidney disease 1 homolog K04985|1|0.0|7830|mmu:18763|polycystin 1 - - - gi|124487380|ref|NP_038658.2|/0/polycystin-1 precursor [Mus musculus] 74706 2194 2.11 1.38 -0.612574732 Down 0.415876866 4930507D05Rik RIKEN cDNA 4930507D05 gene K17675|1|1e-25|121|mmu:338359|ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:3.6.4.13] GO:0005759//mitochondrial matrix;GO:0000177//cytoplasmic exosome (RNase complex) GO:0003724//RNA helicase activity;GO:0042802//identical protein binding;GO:0003723//RNA binding GO:0000963//mitochondrial RNA processing;GO:2000827//mitochondrial RNA surveillance;GO:0006915//apoptotic process;GO:0016049//cell growth;GO:0006325//chromatin organization;GO:0032392//DNA geometric change gi|148700152|gb|EDL32099.1|/5.50189e-45/mCG148087 [Mus musculus] 65111 4628 15.60666667 18.36666667 0.234927384 Up 0.415670014 Dap3 death associated protein 3 K17408|1|0.0|737|mmu:65111|small subunit ribosomal protein S29 GO:0000313;GO:0044429;GO:0031981//nuclear lumen;GO:0044391//ribosomal subunit;GO:0000313;GO:0044429;GO:0031981//nuclear lumen;GO:0044391//ribosomal subunit - GO:0006915//apoptotic process;GO:0006915//apoptotic process "gi|148683296|gb|EDL15243.1|/0/death associated protein 3, isoform CRA_b, partial [Mus musculus]" 69099 1663 5.24 6.55 0.321928095 Up 0.415566588 1810009N02Rik RIKEN cDNA 1810009N02 gene K06287|1|6e-115|417|mmu:69099|septum formation protein - - - gi|21729757|ref|NP_081215.1|/5.14338e-114/acetylserotonin O-methyltransferase-like [Mus musculus] 72097 4361 0.83 0.34 -1.28757659 Down 0.415528978 2010300C02Rik RIKEN cDNA 2010300C02 gene K16522|1|1e-32|145|ngi:103749266|A-kinase anchor protein 5 - - - gi|755492794|ref|XP_006496355.2|/0/PREDICTED: uncharacterized protein KIAA1211-like homolog isoform X2 [Mus musculus] 70394 1665 10.30333333 8.543333333 -0.270240176 Down 0.415510173 Kptn kaptin - GO:0044424 GO:0008092//cytoskeletal protein binding - gi|228480267|ref|NP_598488.2|/0/kaptin [Mus musculus] 66246 1608 20.22666667 23.50333333 0.216606795 Up 0.415491369 Osgep O-sialoglycoprotein endopeptidase K01409|1|0.0|675|mmu:66246|N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234] - - - - 11468 1341 0.966666667 0.446666667 -1.1138199 Down 0.415397345 Actg2 "actin, gamma 2, smooth muscle, enteric" "K12315|1|0.0|777|cge:100768744|actin, gamma-enteric smooth muscle" GO:0032991//macromolecular complex;GO:0005856//cytoskeleton;GO:0043292//contractile fiber GO:0032550 GO:0051707//response to other organism;GO:0006939//smooth muscle contraction;GO:0072008;GO:0008015//blood circulation gi|528767717|gb|EPY87376.1|/0/hypothetical protein CB1_000252031 [Camelus ferus] 76263 930 85.18666667 97.18333333 0.190081278 Up 0.415369138 Gstk1 glutathione S-transferase kappa 1 K13299|1|2e-128|460|mmu:76263|glutathione S-transferase kappa 1 [EC:2.5.1.18] GO:0019866//organelle inner membrane;GO:0042579//microbody;GO:0044429 "GO:0015036//disulfide oxidoreductase activity;GO:0005515//protein binding;GO:0004601//peroxidase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups" GO:0006790//sulfur compound metabolic process;GO:0044710 gi|21313138|ref|NP_083831.1|/1.71185e-127/glutathione S-transferase kappa 1 [Mus musculus] 68875 3544 19.96333333 23.23666667 0.219050495 Up 0.415331528 Tmcc2 transmembrane and coiled-coil domains 2 K16288|1|0.0|744|oaa:100076390|receptor-interacting serine/threonine-protein kinase 5 [EC:2.7.11.1] - - - gi|902763168|ref|NP_001298037.1|/0/transmembrane and coiled-coil domains protein 2 isoform 3 [Mus musculus] 56009 1273 1.453333333 2.19 0.591565236 Up 0.41514348 Alyref2 Aly/REF export factor 2 K12881|1|3e-68|261|mmu:56009|THO complex subunit 4 GO:0043234//protein complex;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0043566//structure-specific DNA binding GO:0000377;GO:0006406//mRNA export from nucleus;GO:0006397//mRNA processing;GO:0006366//transcription from RNA polymerase II promoter gi|148238335|ref|NP_062357.3|/2.48045e-67/aly/REF export factor 2 [Mus musculus] 69101 1320 0.61 1.183333333 0.955975376 Up 0.415115273 Ydjc YdjC homolog (bacterial) - - - - - 57895 2367 1.63 2.403333333 0.560164794 Up 0.415115273 Ccdc126 coiled-coil domain containing 126 "K00744|1|1e-30|137|cmk:103184928|alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase [EC:2.4.1.155]" - - - gi|30424699|ref|NP_780307.1|/1.75378e-52/coiled-coil domain-containing protein 126 isoform 1 precursor [Mus musculus] 14731 2036 10.93333333 13.02666667 0.252734652 Up 0.415068261 Gpaa1 GPI anchor attachment protein 1 K05289|1|0.0|1026|mmu:14731|glycosylphosphatidylinositol transamidase GO:0030176//integral component of endoplasmic reticulum membrane GO:0008092//cytoskeletal protein binding;GO:0035091//phosphatidylinositol binding;GO:0016787//hydrolase activity GO:0035437//maintenance of protein localization in endoplasmic reticulum;GO:0006497//protein lipidation;GO:0065003 gi|6754046|ref|NP_034461.1|/0/glycosylphosphatidylinositol anchor attachment 1 protein [Mus musculus] 73447 4305.88 9.2 7.566666667 -0.281975969 Down 0.414964835 Wdr13 WD repeat domain 13 K14963|1|5e-13|80.1|tru:101079208|COMPASS component SWD3 - - - "gi|45501300|gb|AAH67094.1|/0/WDR13 protein, partial [Homo sapiens]" 229228 1083 19.14333333 22.37333333 0.224938154 Up 0.414804995 Nudt6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 - - - - - 225651 2007 5.263333333 6.56 0.317719049 Up 0.414767385 Mppe1 metallophosphoesterase 1 - GO:0031224//intrinsic component of membrane;GO:0044432;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment GO:0046914//transition metal ion binding;GO:0035091//phosphatidylinositol binding;GO:0042578//phosphoric ester hydrolase activity GO:0016482//cytosolic transport;GO:0006497//protein lipidation "gi|148677712|gb|EDL09659.1|/0/metallophosphoesterase 1, isoform CRA_c, partial [Mus musculus]" 58200 1295 1.566666667 2.323333333 0.568497899 Up 0.414645154 Ppp1r1a "protein phosphatase 1, regulatory (inhibitor) subunit 1A" K08050|1|6e-83|310|mmu:58200|protein phosphatase 1 regulatory subunit 1A - GO:0005488//binding GO:0006073//cellular glucan metabolic process;GO:0044092//negative regulation of molecular function;GO:0007154//cell communication gi|10946734|ref|NP_067366.1|/4.79026e-82/protein phosphatase 1 regulatory subunit 1A [Mus musculus] 12539 2456 78.66666667 90.04666667 0.194920418 Up 0.414569935 Cdc37 cell division cycle 37 K09554|1|0.0|680|mmu:12539|cell division cycle protein 37 - - - - 16601 3263 38.78666667 44.66333333 0.203530131 Up 0.414569935 Klf9 Kruppel-like factor 9 K09208|1|5e-123|445|mmu:16601|krueppel-like factor 9/13/14/16 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0032870//cellular response to hormone stimulus;GO:0071417//cellular response to organonitrogen compound;GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0030518//intracellular steroid hormone receptor signaling pathway" gi|149062591|gb|EDM13014.1|/3.98134e-122/Kruppel-like factor 9 [Rattus norvegicus] 54366 3712 6.84 8.356666667 0.288931265 Up 0.414494716 Ctnnal1 "catenin (cadherin associated protein), alpha-like 1" K18763|1|1e-80|304|bfo:BRAFLDRAFT_86735|la-related protein 4;K05691|2|8e-47|192|crg:105337238|catenin alpha GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0050839//cell adhesion molecule binding GO:0022610;GO:0007265//Ras protein signal transduction gi|227330565|ref|NP_061231.3|/0/alpha-catulin [Mus musculus] 93765 3851 19.35333333 22.56 0.221184996 Up 0.414372485 Ube2n ubiquitin-conjugating enzyme E2N K10580|1|2e-82|310|gja:107118658|ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] GO:0043231//intracellular membrane-bounded organelle;GO:0031371//ubiquitin conjugating enzyme complex;GO:0044444//cytoplasmic part GO:0032182//ubiquitin-like protein binding;GO:0032550;GO:0019787//ubiquitin-like protein transferase activity "GO:0000209//protein polyubiquitination;GO:0000725//recombinational repair;GO:0002753;GO:0031398//positive regulation of protein ubiquitination;GO:0050851//antigen receptor-mediated signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002224//toll-like receptor signaling pathway;GO:0016574//histone ubiquitination;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0000738//DNA catabolic process, exonucleolytic;GO:0019941//modification-dependent protein catabolic process" "gi|148666048|gb|EDK98464.1|/6.335e-91/mCG1038069, partial [Mus musculus]" 24088 2874 1.29 1.996666667 0.630222437 Up 0.414306668 Tlr2 toll-like receptor 2 K10159|1|0.0|1444|mmu:24088|toll-like receptor 2 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0031982//vesicle;GO:0043235//receptor complex;GO:0044424 GO:0005539//glycosaminoglycan binding;GO:0071723//lipopeptide binding;GO:0038023//signaling receptor activity;GO:0046983//protein dimerization activity GO:0006954//inflammatory response;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0016055//Wnt signaling pathway;GO:0043434//response to peptide hormone;GO:0032481//positive regulation of type I interferon production;GO:0022010//central nervous system myelination;GO:0006809//nitric oxide biosynthetic process;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0045687//positive regulation of glial cell differentiation;GO:0071221//cellular response to bacterial lipopeptide;GO:0050663//cytokine secretion;GO:0052263;GO:0042742//defense response to bacterium;GO:0002220;GO:0006690//icosanoid metabolic process;GO:0070391;GO:0052166;GO:0032494//response to peptidoglycan;GO:0001774//microglial cell activation;GO:0048545//response to steroid hormone;GO:0070340;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0002224//toll-like receptor signaling pathway;GO:0010934//macrophage cytokine production;GO:0044126;GO:0001818//negative regulation of cytokine production;GO:0006468//protein phosphorylation;GO:0042891//antibiotic transport;GO:0042345//regulation of NF-kappaB import into nucleus gi|568922750|ref|XP_006501523.1|/0/PREDICTED: toll-like receptor 2 isoform X1 [Mus musculus] 320159 3503 2.006666667 2.84 0.501089943 Up 0.414278461 Fam179a "family with sequence similarity 179, member A" - - - - gi|755556836|ref|XP_006524460.2|/0/PREDICTED: protein FAM179A isoform X2 [Mus musculus] 69743 7199.99 12.76 10.69333333 -0.254916688 Down 0.414278461 Casz1 castor zinc finger 1 - - - - - 102032 1417 25.95333333 30.03 0.210484631 Up 0.414203242 Smim19 small integral membrane protein 19 - GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen - - gi|225735636|ref|NP_001012685.2|/3.19349e-56/small integral membrane protein 19 isoform 1 [Mus musculus] 105704528 746 0.886666667 0.386666667 -1.19730144 Down 0.414005792 Gm13090 predicted gene 13090 - - - - - 100503884 3317 2.463333333 3.363333333 0.449279905 Up 0.413968182 Ccdc149 coiled-coil domain containing 149 K20478|1|1e-10|71.6|aag:AaeL_AAEL007506|golgin subfamily B member 1;K10421|2|5e-10|69.7|tru:101067356|CAP-Gly domain-containing linker protein 1;K08838|5|2e-09|67.8|tca:657573|serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1] - - - gi|568933529|ref|XP_006503682.1|/0/PREDICTED: coiled-coil domain-containing protein 149 isoform X1 [Mus musculus] 66979 1694 8.33 6.816666667 -0.289250058 Down 0.413883561 Pole4 "polymerase (DNA-directed), epsilon 4 (p12 subunit)" K03506|1|4e-38|162|mmu:66979|DNA polymerase epsilon subunit 4 [EC:2.7.7.7] GO:0000123//histone acetyltransferase complex;GO:0000109//nucleotide-excision repair complex GO:0003677//DNA binding;GO:0034061//DNA polymerase activity;GO:0046983//protein dimerization activity GO:0016573//histone acetylation gi|13385366|ref|NP_080158.1|/3.03985e-37/DNA polymerase epsilon subunit 4 [Mus musculus] 16190 5122 7.556666667 9.166666667 0.278647228 Up 0.413827147 Il4ra "interleukin 4 receptor, alpha" K05071|1|0.0|1528|mmu:16190|interleukin 4 receptor GO:0016021//integral component of membrane;GO:0044421 GO:0004896//cytokine receptor activity;GO:0046983//protein dimerization activity GO:0032722//positive regulation of chemokine production;GO:0001562//response to protozoan;GO:0045064//T-helper 2 cell differentiation;GO:0008283//cell proliferation;GO:0045063//T-helper 1 cell differentiation;GO:0048545//response to steroid hormone;GO:0019221//cytokine-mediated signaling pathway;GO:0002696//positive regulation of leukocyte activation;GO:0007292//female gamete generation;GO:0006952//defense response gi|56785428|ref|NP_001008700.1|/0/interleukin-4 receptor subunit alpha precursor [Mus musculus] 228608 2092.59 12.49333333 14.79333333 0.243788715 Up 0.413817744 Smox spermine oxidase K12259|1|0.0|1120|mmu:228608|spermine oxidase [EC:1.5.3.16 1.5.3.-] GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0016647//oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor;GO:0016647//oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor;GO:0016647//oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor;GO:0016647//oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor;GO:0016647//oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor;GO:0016647//oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor;GO:0016647//oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor;GO:0016647//oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor;GO:0016647//oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor" GO:0006598//polyamine catabolic process;GO:0044710;GO:0006598//polyamine catabolic process;GO:0044710;GO:0006598//polyamine catabolic process;GO:0044710;GO:0006598//polyamine catabolic process;GO:0044710;GO:0006598//polyamine catabolic process;GO:0044710;GO:0006598//polyamine catabolic process;GO:0044710;GO:0006598//polyamine catabolic process;GO:0044710;GO:0006598//polyamine catabolic process;GO:0044710;GO:0006598//polyamine catabolic process;GO:0044710 gi|295389757|ref|NP_001171308.1|/0/spermine oxidase isoform f [Mus musculus] 12514 1263 9.496666667 11.34666667 0.256775415 Up 0.413751927 Cd68 CD68 antigen K06501|1|6e-81|302|mmu:12514|CD68 antigen GO:0016020//membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0010033//response to organic substance;GO:0010033//response to organic substance gi|3098526|gb|AAC15685.1|/4.81386e-80/macrosialin [Mus musculus] 217944 3987 1.97 1.266666667 -0.637158712 Down 0.413676708 Rapgef5 Rap guanine nucleotide exchange factor (GEF) 5 K08019|1|0.0|1555|mmu:217944|Rap guanine nucleotide exchange factor 5 - - - gi|238637293|ref|NP_787126.3|/0/rap guanine nucleotide exchange factor 5 [Mus musculus] 223978 2663 29.86333333 25.85 -0.208210927 Down 0.413639099 Cpped1 calcineurin-like phosphoesterase domain containing 1 K18914|1|9e-34|148|tsp:Tsp_06076|adrenodoxin-NADP+ reductase [EC:1.18.1.6] - GO:0043169//cation binding;GO:0003824//catalytic activity - "gi|148664938|gb|EDK97354.1|/0/RIKEN cDNA C530044N13, isoform CRA_b, partial [Mus musculus]" 319596 2105 1.693333333 1.036666667 -0.707913917 Down 0.413592087 D830032E09Rik RIKEN cDNA D830032E09 gene - - - - "gi|148707893|gb|EDL39840.1|/6.16681e-44/mCG145059, isoform CRA_a, partial [Mus musculus]" 100529079 2178 0.093333333 0.486666667 2.382469637 Up 0.413573282 5830418P13Rik RIKEN cDNA 5830418P13 gene K10379|1|2e-30|137|mmu:107993|phakinin - - - - 18701 980 12.98 10.93 -0.247996982 Down 0.41356388 Pigf "phosphatidylinositol glycan anchor biosynthesis, class F" "K05287|1|2e-117|424|mmu:18701|phosphatidylinositol glycan, class F [EC:2.7.-.-]" GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane "GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006497//protein lipidation gi|6679315|ref|NP_032864.1|/1.47624e-116/phosphatidylinositol-glycan biosynthesis class F protein [Mus musculus] 192656 1923 1.773333333 2.563333333 0.531557352 Up 0.413535673 Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 K08846|1|0.0|1095|mmu:192656|receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1] GO:0044444//cytoplasmic part GO:0004713//protein tyrosine kinase activity;GO:0060089;GO:0032550;GO:0042802//identical protein binding;GO:0019904//protein domain specific binding GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006915//apoptotic process;GO:0032481//positive regulation of type I interferon production;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0050851//antigen receptor-mediated signaling pathway;GO:0016567//protein ubiquitination;GO:0043331//response to dsRNA;GO:0043410//positive regulation of MAPK cascade;GO:0042742//defense response to bacterium;GO:0033079;GO:0007254//JNK cascade;GO:0070391;GO:0045063//T-helper 1 cell differentiation;GO:0032872//regulation of stress-activated MAPK cascade;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0032494//response to peptidoglycan;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002824;GO:0006468//protein phosphorylation;GO:0032496//response to lipopolysaccharide;GO:0042102//positive regulation of T cell proliferation gi|20336736|ref|NP_620402.1|/0/receptor-interacting serine/threonine-protein kinase 2 [Mus musculus] 71207 3231 76.18333333 86.73666667 0.187166588 Up 0.413516868 Nudt4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 K07766|1|2e-90|336|mmu:71207|diphosphoinositol-polyphosphate diphosphatase [EC:3.6.1.52] GO:0044424 GO:0043169//cation binding;GO:0003723//RNA binding;GO:0052842//inositol diphosphate pentakisphosphate diphosphatase activity;GO:0052841//inositol bisdiphosphate tetrakisphosphate diphosphatase activity GO:0019932//second-messenger-mediated signaling;GO:0009117//nucleotide metabolic process;GO:0006405//RNA export from nucleus;GO:0006650//glycerophospholipid metabolic process gi|169808397|ref|NP_081998.3|/1.97084e-89/diphosphoinositol polyphosphate phosphohydrolase 2 [Mus musculus] 11853 1082.39 72.96333333 83.42333333 0.193279318 Up 0.413338223 Rhoc ras homolog family member C "K07857|1|4e-107|390|myd:102753125|Ras homolog gene family, member C" GO:0032155;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0001726//ruffle;GO:0016020//membrane;GO:0032155;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0001726//ruffle;GO:0016020//membrane GO:0060089;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0060089;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0032989;GO:0014706//striated muscle tissue development;GO:0033687//osteoblast proliferation;GO:0001503//ossification;GO:0009154//purine ribonucleotide catabolic process;GO:0006935//chemotaxis;GO:0007264//small GTPase mediated signal transduction;GO:0000910//cytokinesis;GO:0031589//cell-substrate adhesion;GO:0009968//negative regulation of signal transduction;GO:0031334//positive regulation of protein complex assembly;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0007043//cell-cell junction assembly;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0051017//actin filament bundle assembly;GO:0043066//negative regulation of apoptotic process;GO:0032989;GO:0014706//striated muscle tissue development;GO:0033687//osteoblast proliferation;GO:0001503//ossification;GO:0009154//purine ribonucleotide catabolic process;GO:0006935//chemotaxis;GO:0007264//small GTPase mediated signal transduction;GO:0000910//cytokinesis;GO:0031589//cell-substrate adhesion;GO:0009968//negative regulation of signal transduction;GO:0031334//positive regulation of protein complex assembly;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0007043//cell-cell junction assembly;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0051017//actin filament bundle assembly;GO:0043066//negative regulation of apoptotic process gi|946639423|ref|XP_006182953.2|/3.93073e-108/PREDICTED: rho-related GTP-binding protein RhoC isoform X1 [Camelus ferus] 240505 5994 6.13 4.89 -0.326052609 Down 0.413310015 Cdc42bpg CDC42 binding protein kinase gamma (DMPK-like) K16307|1|0.0|2761|mmu:240505|serine/threonine-protein kinase MRCK [EC:2.7.11.1] - - - - 12408 1081 24.76666667 28.73333333 0.214325659 Up 0.413291211 Cbr1 carbonyl reductase 1 K00079|1|3e-157|556|mmu:12408|carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197] GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0016020//membrane "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0036094//small molecule binding;GO:0016651//oxidoreductase activity, acting on NAD(P)H" GO:0048545//response to steroid hormone;GO:0008585//female gonad development;GO:0006775;GO:0042374;GO:0002237//response to molecule of bacterial origin;GO:0018193//peptidyl-amino acid modification gi|113680352|ref|NP_031646.2|/2.24157e-156/carbonyl reductase [NADPH] 1 [Mus musculus] 100993 1769 1.296666667 0.71 -0.868916725 Down 0.413263003 AW549542 expressed sequence AW549542 - - - - - 54411 2189 74.32333333 84.71333333 0.188773852 Up 0.413263003 Atp6ap1 "ATPase, H+ transporting, lysosomal accessory protein 1" K03662|1|0.0|837|mmu:54411|V-type H+-transporting ATPase S1 subunit GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0033176//proton-transporting V-type ATPase complex;GO:0031090//organelle membrane GO:0032550;GO:0019829//cation-transporting ATPase activity "GO:0044767//single-organism developmental process;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient" gi|60359906|dbj|BAD90172.1|/0/mFLJ00383 protein [Mus musculus] 68501 1522.91 12.58333333 14.86666667 0.240567066 Up 0.413225394 Nsmce2 "NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase" - GO:0044427;GO:0016604//nuclear body;GO:0000793//condensed chromosome;GO:0044427;GO:0016604//nuclear body;GO:0000793//condensed chromosome GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0000726;GO:0000725//recombinational repair;GO:0007569//cell aging;GO:0034088//maintenance of mitotic sister chromatid cohesion;GO:0000723//telomere maintenance;GO:0032446//protein modification by small protein conjugation;GO:0007091//metaphase/anaphase transition of mitotic cell cycle;GO:0000726;GO:0000725//recombinational repair;GO:0007569//cell aging;GO:0034088//maintenance of mitotic sister chromatid cohesion;GO:0000723//telomere maintenance;GO:0032446//protein modification by small protein conjugation;GO:0007091//metaphase/anaphase transition of mitotic cell cycle gi|257196205|ref|NP_081022.2|/1.86615e-119/E3 SUMO-protein ligase NSE2 isoform 1 [Mus musculus] 269336 1870 8.326666667 6.826666667 -0.286557762 Down 0.413206589 Ccdc32 coiled-coil domain containing 32 - - - - gi|160298152|ref|NP_955014.2|/1.33701e-97/uncharacterized protein C15orf57 homolog [Mus musculus] 192157 7015 6.353333333 5.073333333 -0.32457976 Down 0.413074956 Socs7 suppressor of cytokine signaling 7 K04699|1|0.0|741|mmu:192157|suppressor of cytokine signaling 6/7 - - GO:0032446//protein modification by small protein conjugation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030154//cell differentiation gi|795526550|ref|XP_011901756.1|/0/PREDICTED: LOW QUALITY PROTEIN: suppressor of cytokine signaling 7 [Cercocebus atys] 21872 6916.1 10.08 8.37 -0.268196111 Down 0.413074956 Tjp1 tight junction protein 1 K05701|1|0.0|2823|mmu:21872|tight junction protein 1 GO:0043296//apical junction complex;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0044291//cell-cell contact zone;GO:0070161 GO:0005515//protein binding - gi|568947655|ref|XP_006540845.1|/0/PREDICTED: tight junction protein ZO-1 isoform X6 [Mus musculus] 22436 4623 82.18333333 72.06666667 -0.18951373 Down 0.412868103 Xdh xanthine dehydrogenase K00106|1|0.0|2552|mmu:22436|xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2] GO:0042579//microbody "GO:0046914//transition metal ion binding;GO:0000166//nucleotide binding;GO:0051536//iron-sulfur cluster binding;GO:0016726//oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0050662//coenzyme binding;GO:0042802//identical protein binding;GO:0016727" GO:0006145//purine nucleobase catabolic process;GO:0030857//negative regulation of epithelial cell differentiation;GO:0010467//gene expression;GO:0007589//body fluid secretion;GO:0001935//endothelial cell proliferation;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0006915//apoptotic process;GO:0001932//regulation of protein phosphorylation;GO:0010038//response to metal ion;GO:0072593//reactive oxygen species metabolic process;GO:0001570//vasculogenesis;GO:0001894//tissue homeostasis "gi|148706470|gb|EDL38417.1|/0/xanthine dehydrogenase, isoform CRA_a, partial [Mus musculus]" 20335 754.5 19.05333333 22.16666667 0.218348424 Up 0.412830494 Sec61g "SEC61, gamma subunit" K07342|1|4e-20|87.4|ggo:101124853|protein transport protein SEC61 subunit gamma and related proteins - - - gi|158517832|ref|NP_035473.2|/2.24731e-31/protein transport protein Sec61 subunit gamma isoform 1 [Mus musculus] 67164 1235 3.53 4.58 0.375679415 Up 0.41277408 Lipt2 lipoyl(octanoyl) transferase 2 (putative) K03801|1|6e-125|449|mmu:67164|lipoyl(octanoyl) transferase [EC:2.3.1.181] GO:0043231//intracellular membrane-bounded organelle "GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0005488//binding" GO:0006633//fatty acid biosynthetic process;GO:0036211//protein modification process gi|109731836|gb|AAI15473.1|/4.73563e-124/RIKEN cDNA 2610209A20 gene [Mus musculus] 65973 2702.84 71.65666667 81.68333333 0.188940807 Up 0.412680056 Asph aspartate-beta-hydroxylase K00476|1|9e-51|204|ocu:100008743|aspartate beta-hydroxylase [EC:1.14.11.16] GO:0044448;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0044448;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0044448;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0044448;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0044448;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0071944//cell periphery;GO:0044432;GO:0031224//intrinsic component of membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0044448;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0044448;GO:0033017//sarcoplasmic reticulum membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0043292//contractile fiber;GO:0005788//endoplasmic reticulum lumen;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0034703//cation channel complex;GO:0044448;GO:0033017//sarcoplasmic reticulum membrane "GO:0046872//metal ion binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0046872//metal ion binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0046872//metal ion binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0046872//metal ion binding;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0005198//structural molecule activity;GO:0051213//dioxygenase activity;GO:0046872//metal ion binding;GO:0005515//protein binding" "GO:0006351//transcription, DNA-templated;GO:0035107//appendage morphogenesis;GO:0032388//positive regulation of intracellular transport;GO:0051592//response to calcium ion;GO:1901341//positive regulation of store-operated calcium channel activity;GO:0008283//cell proliferation;GO:0046683//response to organophosphorus;GO:0018126//protein hydroxylation;GO:0044710;GO:0010469//regulation of receptor activity;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0010522//regulation of calcium ion transport into cytosol;GO:0006508//proteolysis;GO:0006351//transcription, DNA-templated;GO:0035107//appendage morphogenesis;GO:0032388//positive regulation of intracellular transport;GO:0051592//response to calcium ion;GO:1901341//positive regulation of store-operated calcium channel activity;GO:0008283//cell proliferation;GO:0046683//response to organophosphorus;GO:0018126//protein hydroxylation;GO:0044710;GO:0010469//regulation of receptor activity;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0010522//regulation of calcium ion transport into cytosol;GO:0006508//proteolysis;GO:0006351//transcription, DNA-templated;GO:0035107//appendage morphogenesis;GO:0032388//positive regulation of intracellular transport;GO:0051592//response to calcium ion;GO:1901341//positive regulation of store-operated calcium channel activity;GO:0008283//cell proliferation;GO:0046683//response to organophosphorus;GO:0018126//protein hydroxylation;GO:0044710;GO:0010469//regulation of receptor activity;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0010522//regulation of calcium ion transport into cytosol;GO:0006508//proteolysis;GO:0006351//transcription, DNA-templated;GO:0035107//appendage morphogenesis;GO:0032388//positive regulation of intracellular transport;GO:0051592//response to calcium ion;GO:1901341//positive regulation of store-operated calcium channel activity;GO:0008283//cell proliferation;GO:0046683//response to organophosphorus;GO:0018126//protein hydroxylation;GO:0044710;GO:0010469//regulation of receptor activity;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0010522//regulation of calcium ion transport into cytosol;GO:0006508//proteolysis;GO:0006351//transcription, DNA-templated;GO:0035107//appendage morphogenesis;GO:0032388//positive regulation of intracellular transport;GO:0051592//response to calcium ion;GO:1901341//positive regulation of store-operated calcium channel activity;GO:0008283//cell proliferation;GO:0046683//response to organophosphorus;GO:0018126//protein hydroxylation;GO:0044710;GO:0010469//regulation of receptor activity;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0010522//regulation of calcium ion transport into cytosol;GO:0006508//proteolysis;GO:0035107//appendage morphogenesis;GO:0051716//cellular response to stimulus;GO:0042221//response to chemical;GO:0032388//positive regulation of intracellular transport;GO:0008283//cell proliferation;GO:2001257//regulation of cation channel activity;GO:0018126//protein hydroxylation;GO:0044093;GO:1901019//regulation of calcium ion transmembrane transporter activity;GO:0019222//regulation of metabolic process;GO:0035107//appendage morphogenesis;GO:0065009;GO:0051050//positive regulation of transport;GO:0008283//cell proliferation;GO:0018126//protein hydroxylation;GO:0051924//regulation of calcium ion transport;GO:0050896//response to stimulus;GO:0034220//ion transmembrane transport;GO:0050794//regulation of cellular process;GO:0019222//regulation of metabolic process;GO:0006351//transcription, DNA-templated;GO:0035107//appendage morphogenesis;GO:0032388//positive regulation of intracellular transport;GO:0051592//response to calcium ion;GO:1901341//positive regulation of store-operated calcium channel activity;GO:0008283//cell proliferation;GO:0046683//response to organophosphorus;GO:0018126//protein hydroxylation;GO:0044710;GO:0010469//regulation of receptor activity;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0010522//regulation of calcium ion transport into cytosol;GO:0006508//proteolysis;GO:0035107//appendage morphogenesis;GO:0065009;GO:0051050//positive regulation of transport;GO:0008283//cell proliferation;GO:0018126//protein hydroxylation;GO:0051924//regulation of calcium ion transport;GO:0050896//response to stimulus;GO:0034220//ion transmembrane transport;GO:0050794//regulation of cellular process;GO:0019222//regulation of metabolic process;GO:0006351//transcription, DNA-templated;GO:0035107//appendage morphogenesis;GO:0032388//positive regulation of intracellular transport;GO:0051592//response to calcium ion;GO:1901341//positive regulation of store-operated calcium channel activity;GO:0008283//cell proliferation;GO:0046683//response to organophosphorus;GO:0018126//protein hydroxylation;GO:0044710;GO:0010469//regulation of receptor activity;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0010522//regulation of calcium ion transport into cytosol;GO:0006508//proteolysis;GO:0035107//appendage morphogenesis;GO:0003012//muscle system process;GO:0032388//positive regulation of intracellular transport;GO:1901341//positive regulation of store-operated calcium channel activity;GO:0010644//cell communication by electrical coupling;GO:0018126//protein hydroxylation;GO:0006351//transcription, DNA-templated;GO:0010469//regulation of receptor activity;GO:0006508//proteolysis;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0051592//response to calcium ion;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0046683//response to organophosphorus;GO:0008283//cell proliferation;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0009593//detection of chemical stimulus" gi|295390538|ref|NP_001171321.1|/3.64888e-111/aspartyl/asparaginyl beta-hydroxylase isoform 4 [Mus musculus] 353310 3194.31 12.49 14.75 0.239941478 Up 0.412576629 Zfp703 zinc finger protein 703 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0008134//transcription factor binding;GO:0008134//transcription factor binding "GO:0006351//transcription, DNA-templated;GO:0033598//mammary gland epithelial cell proliferation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001837//epithelial to mesenchymal transition;GO:0030111//regulation of Wnt signaling pathway;GO:0022408//negative regulation of cell-cell adhesion;GO:0034329//cell junction assembly;GO:0030855//epithelial cell differentiation;GO:0016477//cell migration;GO:0007049//cell cycle;GO:0006351//transcription, DNA-templated;GO:0033598//mammary gland epithelial cell proliferation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001837//epithelial to mesenchymal transition;GO:0030111//regulation of Wnt signaling pathway;GO:0022408//negative regulation of cell-cell adhesion;GO:0034329//cell junction assembly;GO:0030855//epithelial cell differentiation;GO:0016477//cell migration;GO:0007049//cell cycle" gi|160333268|ref|NP_001094972.1|/0/zinc finger protein 703 isoform 1 [Mus musculus] 74310 778 1.243333333 0.666666667 -0.89917563 Down 0.412548422 Ube4bos3 "ubiquitination factor E4B, opposite strand 3" K10597|1|9e-07|56.2|cmk:103184239|ubiquitin conjugation factor E4 B [EC:2.3.2.27] - - - - 56461 2928 2.816666667 1.993333333 -0.498805857 Down 0.412492008 Kcnip3 "Kv channel interacting protein 3, calsenilin" K16575|1|5e-91|338|aam:106493806|centractin;K19932|2|2e-41|174|nve:NEMVE_v1g239489|neuronal calcium sensor 1 GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0033267;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0033267;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0005261//cation channel activity;GO:0046872//metal ion binding;GO:0016247//channel regulator activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0005261//cation channel activity;GO:0046872//metal ion binding;GO:0016247//channel regulator activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0042981//regulation of apoptotic process;GO:0033555//multicellular organismal response to stress;GO:0030001//metal ion transport;GO:0015031//protein transport;GO:0007600//sensory perception;GO:0034220//ion transmembrane transport;GO:0006351//transcription, DNA-templated;GO:0042981//regulation of apoptotic process;GO:0033555//multicellular organismal response to stress;GO:0030001//metal ion transport;GO:0015031//protein transport;GO:0007600//sensory perception;GO:0034220//ion transmembrane transport" gi|162461446|ref|NP_001104801.1|/2.78737e-119/calsenilin isoform b precursor [Mus musculus] 14469 2471 9.266666667 11.09 0.259136983 Up 0.41234157 Gbp2 guanylate binding protein 2 K17339|1|1e-19|101|crg:105327935|atlastin [EC:3.6.5.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0020003//symbiont-containing vacuole GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0032496//response to lipopolysaccharide;GO:0001562//response to protozoan;GO:0042742//defense response to bacterium;GO:0002252;GO:0034341//response to interferon-gamma;GO:0009154//purine ribonucleotide catabolic process;GO:0051702//interaction with symbiont;GO:0035456//response to interferon-beta gi|6753950|ref|NP_034390.1|/0/guanylate-binding protein 1 [Mus musculus] 243547 5143 4.733333333 5.96 0.332455807 Up 0.412285156 Grip2 glutamate receptor interacting protein 2 K20251|1|0.0|1902|mmu:243547|glutamate receptor-interacting protein GO:0044327//dendritic spine head;GO:0043231//intracellular membrane-bounded organelle;GO:0097060//synaptic membrane GO:0005102//receptor binding GO:0045184//establishment of protein localization gi|226958407|ref|NP_001152979.1|/0/glutamate receptor-interacting protein 2 [Mus musculus] 84035 4943 42.56 37.16333333 -0.195618242 Down 0.412097108 Kremen1 kringle containing transmembrane protein 1 K01315|1|7e-17|93.2|bfo:BRAFLDRAFT_209183|plasminogen [EC:3.4.21.7];K01343|3|9e-17|92.8|mgp:100542402|tissue plasminogen activator [EC:3.4.21.68] GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0048513//animal organ development;GO:0030111//regulation of Wnt signaling pathway "gi|148708579|gb|EDL40526.1|/0/kringle containing transmembrane protein 1, partial [Mus musculus]" 217737 1330 69.67 79.30666667 0.186904583 Up 0.412078303 Ahsa1 "AHA1, activator of heat shock protein ATPase 1" - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0008047//enzyme activator activity;GO:0005515//protein binding GO:0050896//response to stimulus;GO:0044267//cellular protein metabolic process;GO:0043462//regulation of ATPase activity gi|74177617|dbj|BAE38913.1|/0/unnamed protein product [Mus musculus] 19655 2420.02 12.63 14.87333333 0.235873374 Up 0.41194667 Rbmx "RNA binding motif protein, X chromosome" K12885|1|1e-113|413|cge:100762511|heterogeneous nuclear ribonucleoprotein G GO:0031988//membrane-bounded vesicle;GO:0005681//spliceosomal complex;GO:0000790//nuclear chromatin;GO:0031988//membrane-bounded vesicle;GO:0005681//spliceosomal complex;GO:0000790//nuclear chromatin;GO:0031988//membrane-bounded vesicle;GO:0005681//spliceosomal complex;GO:0000790//nuclear chromatin GO:0044212//transcription regulatory region DNA binding;GO:0003723//RNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003723//RNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003723//RNA binding "GO:0006366//transcription from RNA polymerase II promoter;GO:0000245//spliceosomal complex assembly;GO:0070555//response to interleukin-1;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0033619//membrane protein proteolysis;GO:0006366//transcription from RNA polymerase II promoter;GO:0000245//spliceosomal complex assembly;GO:0070555//response to interleukin-1;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0033619//membrane protein proteolysis;GO:0006366//transcription from RNA polymerase II promoter;GO:0000245//spliceosomal complex assembly;GO:0070555//response to interleukin-1;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0033619//membrane protein proteolysis" "gi|625268548|ref|XP_007625783.1|/1.01435e-100/PREDICTED: RNA-binding motif protein, X chromosome isoform X1 [Cricetulus griseus]" 103012 5832 3.72 2.776666667 -0.421948626 Down 0.411871451 Firre functional intergenic repeating RNA element - - - - - 78245 535 0.01 0.29 4.857980995 Up 0.411843243 Acbd7 acyl-Coenzyme A binding domain containing 7 "K08762|1|7e-25|115|ptg:102963871|diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein)" - GO:0043168//anion binding - gi|164414722|ref|NP_084339.1|/2.12324e-43/acyl-CoA-binding domain-containing protein 7 [Mus musculus] 102635561 550.01 2.68 1.876666667 -0.514060579 Down 0.411739817 Ggnbp2os "gametogenetin binding protein 2, opposite strand" - - - - - 22187 1395.09 841.9566667 950.7166667 0.175269469 Up 0.41171161 Ubb ubiquitin B K08770|1|5e-163|576|oaa:100085779|ubiquitin C - - - - 17748 583 859.67 758.72 -0.180215393 Down 0.411636391 Mt1 metallothionein 1 - - - - "gi|148679171|gb|EDL11118.1|/3.75818e-08/metallothionein 1, isoform CRA_a, partial [Mus musculus]" 69740 1610 4.676666667 3.61 -0.373481766 Down 0.411617586 Dph5 diphthamide biosynthesis 5 K00586|1|2e-157|558|mmu:69740|diphthine methyl ester synthase [EC:2.1.1.314] - - - - 17132 3642 3.656666667 4.726666667 0.370294007 Up 0.411617586 Maf avian musculoaponeurotic fibrosarcoma oncogene homolog K09035|1|7e-59|232|mmu:17132|transcription factor Maf - - - - 242109 5170 1.353333333 2.066666667 0.610788488 Up 0.411579977 Zfp697 zinc finger protein 697 K09228|1|1e-98|364|cmy:102942191|KRAB domain-containing zinc finger protein - - - - 74761 2280 14.50333333 17.05 0.233387223 Up 0.411448343 Mxra8 matrix-remodelling associated 8 K02353|1|4e-14|82.8|umr:103682075|segment polarity protein dishevelled - - - - 110074 2269.38 4.84 6.063333333 0.32510409 Up 0.411401331 Dut deoxyuridine triphosphatase K01520|1|1e-76|290|mmu:110074|dUTP pyrophosphatase [EC:3.6.1.23] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0019103//pyrimidine nucleotide binding;GO:0005102//receptor binding;GO:0043169//cation binding;GO:0047429//nucleoside-triphosphate diphosphatase activity;GO:0030545;GO:0019103//pyrimidine nucleotide binding;GO:0005102//receptor binding;GO:0043169//cation binding;GO:0047429//nucleoside-triphosphate diphosphatase activity;GO:0030545 GO:0006213//pyrimidine nucleoside metabolic process;GO:0043393//regulation of protein binding;GO:0010033//response to organic substance;GO:0006259//DNA metabolic process;GO:0009177;GO:0010469//regulation of receptor activity;GO:0009112;GO:0009213//pyrimidine deoxyribonucleoside triphosphate catabolic process;GO:0051260//protein homooligomerization;GO:0043393//regulation of protein binding;GO:0010033//response to organic substance;GO:0009177;GO:0010469//regulation of receptor activity;GO:0009213//pyrimidine deoxyribonucleoside triphosphate catabolic process;GO:0051260//protein homooligomerization "gi|21281687|ref|NP_076084.2|/1.06873e-75/deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform 2 [Mus musculus]" 21679 2947 1.733333333 1.073333333 -0.691450935 Down 0.411203881 Tead4 TEA domain family member 4 K09448|1|0.0|774|mmu:21679|transcriptional enhancer factor GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0035556//intracellular signal transduction;GO:0045165//cell fate commitment;GO:0001829//trophectodermal cell differentiation;GO:0006366//transcription from RNA polymerase II promoter "gi|148667459|gb|EDK99875.1|/0/TEA domain family member 4, isoform CRA_f, partial [Mus musculus]" 22763 4612 14.20666667 11.99666667 -0.243934491 Down 0.411044041 Zfr zinc finger RNA binding protein K13203|1|0.0|1155|mmu:22763|zinc finger RNA-binding protein GO:0043229//intracellular organelle GO:0003676//nucleic acid binding - gi|148671325|gb|EDL03272.1|/0/zinc finger RNA binding protein [Mus musculus] 80915 1413 4.166666667 5.296666667 0.34619103 Up 0.411025236 Dusp12 dual specificity phosphatase 12 K14819|1|0.0|691|mmu:80915|dual specificity phosphatase 12 [EC:3.1.3.16 3.1.3.48] - - - gi|70778930|ref|NP_075662.2|/0/dual specificity protein phosphatase 12 [Mus musculus] NM_001254730 1812 0.5 0.103333333 -2.27462238 Down 0.410940615 - - "K04679|1|4e-34|148|rno:313477|MAD, mothers against decapentaplegic interacting protein" - - - gi|568928876|ref|XP_006503049.1|/6.30008e-37/PREDICTED: zinc finger FYVE domain-containing protein 9 isoform X1 [Mus musculus] 227753 2662.43 577.3833333 509.1033333 -0.181570952 Down 0.410903005 Gsn gelsolin K05768|1|0.0|1493|mmu:227753|gelsolin GO:0032991//macromolecular complex;GO:0031988//membrane-bounded vesicle;GO:0031252//cell leading edge;GO:0005856//cytoskeleton;GO:0044421;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0031988//membrane-bounded vesicle;GO:0031252//cell leading edge;GO:0005856//cytoskeleton;GO:0044421;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0031988//membrane-bounded vesicle;GO:0031252//cell leading edge;GO:0005856//cytoskeleton;GO:0044421;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0031988//membrane-bounded vesicle;GO:0031252//cell leading edge;GO:0005856//cytoskeleton;GO:0044421;GO:0044444//cytoplasmic part GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding;GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding;GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding;GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding GO:0006810//transport;GO:0009888//tissue development;GO:0009611//response to wounding;GO:0007155//cell adhesion;GO:0030835//negative regulation of actin filament depolymerization;GO:0012501//programmed cell death;GO:0048017//inositol lipid-mediated signaling;GO:0014070//response to organic cyclic compound;GO:0048858//cell projection morphogenesis;GO:0046686//response to cadmium ion;GO:0097305//response to alcohol;GO:0021782//glial cell development;GO:0006810//transport;GO:0009888//tissue development;GO:0009611//response to wounding;GO:0007155//cell adhesion;GO:0030835//negative regulation of actin filament depolymerization;GO:0012501//programmed cell death;GO:0048017//inositol lipid-mediated signaling;GO:0014070//response to organic cyclic compound;GO:0048858//cell projection morphogenesis;GO:0046686//response to cadmium ion;GO:0097305//response to alcohol;GO:0021782//glial cell development;GO:0006810//transport;GO:0009888//tissue development;GO:0009611//response to wounding;GO:0007155//cell adhesion;GO:0030835//negative regulation of actin filament depolymerization;GO:0012501//programmed cell death;GO:0048017//inositol lipid-mediated signaling;GO:0014070//response to organic cyclic compound;GO:0048858//cell projection morphogenesis;GO:0046686//response to cadmium ion;GO:0097305//response to alcohol;GO:0021782//glial cell development;GO:0006810//transport;GO:0009888//tissue development;GO:0009611//response to wounding;GO:0007155//cell adhesion;GO:0030835//negative regulation of actin filament depolymerization;GO:0012501//programmed cell death;GO:0048017//inositol lipid-mediated signaling;GO:0014070//response to organic cyclic compound;GO:0048858//cell projection morphogenesis;GO:0046686//response to cadmium ion;GO:0097305//response to alcohol;GO:0021782//glial cell development gi|568913585|ref|XP_006498053.1|/0/PREDICTED: gelsolin isoform X2 [Mus musculus] 67059 2189 21.17333333 18.17333333 -0.22042535 Down 0.410780774 Ola1 Obg-like ATPase 1 K19788|1|3e-131|464|pps:100990203|obg-like ATPase 1 - - - - 19166 963 64.90666667 73.8 0.185254149 Up 0.410771372 Psma2 "proteasome (prosome, macropain) subunit, alpha type 2" K02726|1|1e-130|468|rno:29669|20S proteasome subunit alpha 2 [EC:3.4.25.1] GO:0031981//nuclear lumen;GO:0005839//proteasome core complex;GO:0035770//ribonucleoprotein granule;GO:0044444//cytoplasmic part GO:0004175//endopeptidase activity;GO:0005488//binding "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0051707//response to other organism;GO:0006915//apoptotic process;GO:0044764;GO:0051320;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|984108703|ref|XP_015345737.1|/3.18454e-132/PREDICTED: proteasome subunit alpha type-2 [Marmota marmota marmota] 56199 4325 14.46 12.26 -0.238108573 Down 0.410761969 Abcb10 "ATP-binding cassette, sub-family B (MDR/TAP), member 10" "K05657|1|0.0|1286|mmu:56199|ATP-binding cassette, subfamily B (MDR/TAP), member 10" - - - "gi|9506367|ref|NP_062425.1|/0/ATP-binding cassette sub-family B member 10, mitochondrial precursor [Mus musculus]" 100303740 116 0.643333333 1.21 0.911368701 Up 0.410743164 Snora75 "small nucleolar RNA, H/ACA box 75" - - - - - 100503536 2946 2.21 3.06 0.469485283 Up 0.410639738 Gm19757 "predicted gene, 19757" - - - - - 619605 1411 17.91 20.89333333 0.222277342 Up 0.410357667 Zcchc17 "zinc finger, CCHC domain containing 17" K11723|1|6e-95|350|ocu:100357793|bromodomain-containing protein 7/9;K15178|2|8e-89|330|chx:102170745|RNA polymerase-associated protein RTF1;K12818|3|2e-09|66.2|acs:100564259|ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13] GO:0015934//large ribosomal subunit;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - gi|521031426|gb|EPQ13212.1|/3.48368e-105/Nucleolar protein of 40 kDa [Myotis brandtii] 20850 3910 8.996666667 10.78 0.260894702 Up 0.410357667 Stat5a signal transducer and activator of transcription 5A K11223|1|0.0|1566|mmu:20850|signal transducer and activator of transcription 5A GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0060089;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0043566//structure-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0060089;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0043566//structure-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding GO:0033024;GO:0008202//steroid metabolic process;GO:0001779//natural killer cell differentiation;GO:0006954//inflammatory response;GO:0072350//tricarboxylic acid metabolic process;GO:0010876//lipid localization;GO:0043648//dicarboxylic acid metabolic process;GO:0002260//lymphocyte homeostasis;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0042094//interleukin-2 biosynthetic process;GO:0032787//monocarboxylic acid metabolic process;GO:0035264//multicellular organism growth;GO:0007259//JAK-STAT cascade;GO:0002009//morphogenesis of an epithelium;GO:0007589//body fluid secretion;GO:0072338;GO:0048771//tissue remodeling;GO:0009081//branched-chain amino acid metabolic process;GO:0006790//sulfur compound metabolic process;GO:0000278//mitotic cell cycle;GO:0042492//gamma-delta T cell differentiation;GO:0030183//B cell differentiation;GO:0007166//cell surface receptor signaling pathway;GO:0045136//development of secondary sexual characteristics;GO:0009991//response to extracellular stimulus;GO:0044703;GO:0006366//transcription from RNA polymerase II promoter;GO:0007155//cell adhesion;GO:0030855//epithelial cell differentiation;GO:0008585//female gonad development;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0030879//mammary gland development;GO:0030218//erythrocyte differentiation;GO:0009725//response to hormone;GO:0097305//response to alcohol;GO:0006468//protein phosphorylation;GO:0070662//mast cell proliferation;GO:0048537//mucosal-associated lymphoid tissue development;GO:0006575//cellular modified amino acid metabolic process;GO:0042102//positive regulation of T cell proliferation;GO:0033024;GO:0008202//steroid metabolic process;GO:0001779//natural killer cell differentiation;GO:0006954//inflammatory response;GO:0072350//tricarboxylic acid metabolic process;GO:0010876//lipid localization;GO:0043648//dicarboxylic acid metabolic process;GO:0002260//lymphocyte homeostasis;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0042094//interleukin-2 biosynthetic process;GO:0032787//monocarboxylic acid metabolic process;GO:0035264//multicellular organism growth;GO:0007259//JAK-STAT cascade;GO:0002009//morphogenesis of an epithelium;GO:0007589//body fluid secretion;GO:0072338;GO:0048771//tissue remodeling;GO:0009081//branched-chain amino acid metabolic process;GO:0006790//sulfur compound metabolic process;GO:0000278//mitotic cell cycle;GO:0042492//gamma-delta T cell differentiation;GO:0030183//B cell differentiation;GO:0007166//cell surface receptor signaling pathway;GO:0045136//development of secondary sexual characteristics;GO:0009991//response to extracellular stimulus;GO:0044703;GO:0006366//transcription from RNA polymerase II promoter;GO:0007155//cell adhesion;GO:0030855//epithelial cell differentiation;GO:0008585//female gonad development;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0030879//mammary gland development;GO:0030218//erythrocyte differentiation;GO:0009725//response to hormone;GO:0097305//response to alcohol;GO:0006468//protein phosphorylation;GO:0070662//mast cell proliferation;GO:0048537//mucosal-associated lymphoid tissue development;GO:0006575//cellular modified amino acid metabolic process;GO:0042102//positive regulation of T cell proliferation gi|255759968|ref|NP_001157534.1|/0/signal transducer and activator of transcription 5A isoform 2 [Mus musculus] 20362 4500.36 16.96333333 14.45 -0.231350198 Down 0.410320057 8-Sep septin 8 K16939|1|0.0|728|mmu:20362|septin 6/8/11 GO:0032156//septin cytoskeleton;GO:0032156//septin cytoskeleton;GO:0032156//septin cytoskeleton GO:0032550;GO:0032550;GO:0032550 GO:0044763;GO:0044763;GO:0044763 "gi|148701638|gb|EDL33585.1|/0/septin 8, isoform CRA_c, partial [Mus musculus]" 17344 3361.4 6.936666667 5.613333333 -0.305384827 Down 0.410263643 Pias2 protein inhibitor of activated STAT 2 K16063|1|0.0|1018|mmu:17344|E3 SUMO-protein ligase PIAS2 GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0044451 GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0035258//steroid hormone receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0035258//steroid hormone receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003676//nucleic acid binding;GO:0035258//steroid hormone receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003676//nucleic acid binding;GO:0035258//steroid hormone receptor binding;GO:0019787//ubiquitin-like protein transferase activity GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031346//positive regulation of cell projection organization;GO:0030521//androgen receptor signaling pathway;GO:0032446//protein modification by small protein conjugation;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031346//positive regulation of cell projection organization;GO:0030521//androgen receptor signaling pathway;GO:0048545//response to steroid hormone;GO:0048232//male gamete generation;GO:0032446//protein modification by small protein conjugation;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031346//positive regulation of cell projection organization;GO:0030521//androgen receptor signaling pathway;GO:0048545//response to steroid hormone;GO:0048232//male gamete generation;GO:0032446//protein modification by small protein conjugation;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031346//positive regulation of cell projection organization;GO:0030521//androgen receptor signaling pathway;GO:0032446//protein modification by small protein conjugation gi|255918216|ref|NP_001157640.1|/0/E3 SUMO-protein ligase PIAS2 isoform 3 [Mus musculus] 20869 2522.2 61.44333333 70.06333333 0.189403142 Up 0.410244838 Stk11 serine/threonine kinase 11 K07298|1|0.0|702|mmu:20869|serine/threonine-protein kinase 11 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0019887//protein kinase regulator activity;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0019887//protein kinase regulator activity;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0019887//protein kinase regulator activity;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0019887//protein kinase regulator activity GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006915//apoptotic process;GO:0016055//Wnt signaling pathway;GO:0048871//multicellular organismal homeostasis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0044248;GO:0072331//signal transduction by p53 class mediator;GO:0022402//cell cycle process;GO:0016049//cell growth;GO:0009314//response to radiation;GO:0007163//establishment or maintenance of cell polarity;GO:0007409//axonogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0033500//carbohydrate homeostasis;GO:0007281//germ cell development;GO:0033554//cellular response to stress;GO:0051259//protein oligomerization;GO:0006094//gluconeogenesis;GO:0051640//organelle localization;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006915//apoptotic process;GO:0016055//Wnt signaling pathway;GO:0048871//multicellular organismal homeostasis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0044248;GO:0072331//signal transduction by p53 class mediator;GO:0022402//cell cycle process;GO:0016049//cell growth;GO:0009314//response to radiation;GO:0007163//establishment or maintenance of cell polarity;GO:0007409//axonogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0033500//carbohydrate homeostasis;GO:0007281//germ cell development;GO:0033554//cellular response to stress;GO:0051259//protein oligomerization;GO:0006094//gluconeogenesis;GO:0051640//organelle localization;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006915//apoptotic process;GO:0016055//Wnt signaling pathway;GO:0048871//multicellular organismal homeostasis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0044248;GO:0072331//signal transduction by p53 class mediator;GO:0022402//cell cycle process;GO:0016049//cell growth;GO:0009314//response to radiation;GO:0007163//establishment or maintenance of cell polarity;GO:0007409//axonogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0033500//carbohydrate homeostasis;GO:0007281//germ cell development;GO:0033554//cellular response to stress;GO:0051259//protein oligomerization;GO:0006094//gluconeogenesis;GO:0051640//organelle localization;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006915//apoptotic process;GO:0016055//Wnt signaling pathway;GO:0048871//multicellular organismal homeostasis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0044248;GO:0072331//signal transduction by p53 class mediator;GO:0022402//cell cycle process;GO:0016049//cell growth;GO:0009314//response to radiation;GO:0007163//establishment or maintenance of cell polarity;GO:0007409//axonogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0033500//carbohydrate homeostasis;GO:0007281//germ cell development;GO:0033554//cellular response to stress;GO:0051259//protein oligomerization;GO:0006094//gluconeogenesis;GO:0051640//organelle localization gi|687569592|ref|NP_001288782.1|/0/serine/threonine-protein kinase STK11 isoform S [Mus musculus] 209357 2664 4.353333333 5.516666667 0.34167632 Up 0.410160217 Gtf2h3 "general transcription factor IIH, polypeptide 3" K03143|1|3e-163|578|mmu:209357|transcription initiation factor TFIIH subunit 3 GO:0005667//transcription factor complex "GO:0043169//cation binding;GO:0004674//protein serine/threonine kinase activity;GO:0042623//ATPase activity, coupled;GO:0005515//protein binding" "GO:0006281//DNA repair;GO:0006464//cellular protein modification process;GO:0006351//transcription, DNA-templated" gi|31088894|ref|NP_852075.1|/2.38759e-162/general transcription factor IIH subunit 3 [Mus musculus] 15945 1120 0.31 0.776666667 1.325027334 Up 0.4100944 Cxcl10 chemokine (C-X-C motif) ligand 10 K12671|1|3e-49|198|mmu:15945|C-X-C motif chemokine 10 GO:0009986//cell surface;GO:0044421 GO:0005125//cytokine activity GO:0001525//angiogenesis;GO:0009612//response to mechanical stimulus;GO:0008283//cell proliferation;GO:0015031//protein transport;GO:0002687//positive regulation of leukocyte migration;GO:0048513//animal organ development;GO:0007154//cell communication;GO:0002252;GO:0014070//response to organic cyclic compound;GO:0009408//response to heat;GO:0010212//response to ionizing radiation;GO:0002237//response to molecule of bacterial origin;GO:0006952//defense response gi|10946576|ref|NP_067249.1|/2.14507e-48/C-X-C motif chemokine 10 precursor [Mus musculus] 73047 1299 1.03 1.676666667 0.702951562 Up 0.410066193 Camk2n2 calcium/calmodulin-dependent protein kinase II inhibitor 2 - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0004860//protein kinase inhibitor activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019900//kinase binding" GO:0050804//modulation of synaptic transmission;GO:0006796//phosphate-containing compound metabolic process gi|11067401|ref|NP_067710.1|/9.54607e-30/calcium/calmodulin-dependent protein kinase II inhibitor 2 [Rattus norvegicus] 69068 1331 59.94 68.49666667 0.192514698 Up 0.41005679 1810011O10Rik RIKEN cDNA 1810011O10 gene - - - GO:0012501//programmed cell death gi|21312200|ref|NP_081207.1|/4.55648e-51/protein C8orf4 homolog [Mus musculus] 18828 1895 12.29666667 10.34666667 -0.249101232 Down 0.409652488 Plscr2 phospholipid scramblase 2 - GO:0031981//nuclear lumen;GO:0016021//integral component of membrane;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0016021//integral component of membrane;GO:0044444//cytoplasmic part GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0019904//protein domain specific binding;GO:0070851//growth factor receptor binding;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0019904//protein domain specific binding;GO:0070851//growth factor receptor binding GO:0030097//hemopoiesis;GO:0010912;GO:0006915//apoptotic process;GO:0019079//viral genome replication;GO:0007009//plasma membrane organization;GO:0031349//positive regulation of defense response;GO:0006658//phosphatidylserine metabolic process;GO:0009411//response to UV;GO:0002431//Fc receptor mediated stimulatory signaling pathway;GO:0043393//regulation of protein binding;GO:0002252;GO:0006366//transcription from RNA polymerase II promoter;GO:0035556//intracellular signal transduction;GO:0034097//response to cytokine;GO:0002694;GO:0032496//response to lipopolysaccharide;GO:0030097//hemopoiesis;GO:0010912;GO:0006915//apoptotic process;GO:0019079//viral genome replication;GO:0007009//plasma membrane organization;GO:0031349//positive regulation of defense response;GO:0006658//phosphatidylserine metabolic process;GO:0009411//response to UV;GO:0002431//Fc receptor mediated stimulatory signaling pathway;GO:0043393//regulation of protein binding;GO:0002252;GO:0006366//transcription from RNA polymerase II promoter;GO:0035556//intracellular signal transduction;GO:0034097//response to cytokine;GO:0002694;GO:0032496//response to lipopolysaccharide gi|755529790|ref|XP_011240977.1|/1.97964e-173/PREDICTED: phospholipid scramblase 2 isoform X1 [Mus musculus] 68982 1883 0.523333333 1.046666667 1 Up 0.409605476 1500015A07Rik RIKEN cDNA 1500015A07 gene - - - - - 97820 2451.43 59.56666667 67.91666667 0.189260425 Up 0.409586671 4833439L19Rik RIKEN cDNA 4833439L19 gene - GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0044710;GO:0044710;GO:0044710;GO:0044710;GO:0044710 gi|50510837|dbj|BAD32404.1|/0/mKIAA1191 protein [Mus musculus] 99031 8055.16 2.043333333 1.343333333 -0.605107235 Down 0.409492647 Osbpl6 oxysterol binding protein-like 6 K20463|1|0.0|1783|mcf:102145053|oxysterol-binding protein-related protein 3/6/7 GO:0044432;GO:0005635//nuclear envelope;GO:0016020//membrane;GO:0044432;GO:0005635//nuclear envelope;GO:0016020//membrane;GO:0044432;GO:0005635//nuclear envelope;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044446 GO:0008289//lipid binding;GO:0008289//lipid binding;GO:0008289//lipid binding GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0010876//lipid localization;GO:0051234//establishment of localization gi|60360532|dbj|BAD90510.1|/0/mKIAA4128 protein [Mus musculus] 75494 799 0.693333333 0.24 -1.530514717 Down 0.409436233 1700008C04Rik RIKEN cDNA 1700008C04 gene - - - - - 193796 4610 14.03666667 11.87333333 -0.241475359 Down 0.409370416 Kdm4b lysine (K)-specific demethylase 4B K06709|1|0.0|2019|mmu:193796|jumonji domain-containing protein 2 [EC:1.14.11.-] - "GO:0046914//transition metal ion binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" "GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization;GO:0044710" gi|26006857|ref|NP_742144.1|/0/lysine-specific demethylase 4B [Mus musculus] 101568 1790 14.22333333 16.68666667 0.23043618 Up 0.409182369 Vrk3 vaccinia related kinase 3 K08816|1|0.0|935|mmu:101568|vaccinia related kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0019902//phosphatase binding;GO:0016301//kinase activity GO:0043409//negative regulation of MAPK cascade;GO:0010922//positive regulation of phosphatase activity;GO:0006464//cellular protein modification process "gi|148690802|gb|EDL22749.1|/0/vaccinia related kinase 3, isoform CRA_a, partial [Mus musculus]" 77980 6268 20.21 17.32333333 -0.222352763 Down 0.408956711 Sbf1 SET binding factor 1 K18061|1|0.0|3486|rno:300147|myotubularin-related protein 5/13 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0042578//phosphoric ester hydrolase activity;GO:0008289//lipid binding;GO:0019212//phosphatase inhibitor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0042578//phosphoric ester hydrolase activity;GO:0008289//lipid binding;GO:0019212//phosphatase inhibitor activity GO:0006796//phosphate-containing compound metabolic process;GO:0048232//male gamete generation;GO:0044092//negative regulation of molecular function;GO:0006796//phosphate-containing compound metabolic process;GO:0048232//male gamete generation;GO:0044092//negative regulation of molecular function gi|281604100|ref|NP_001164032.1|/0/myotubularin-related protein 5 isoform 1 [Mus musculus] 384281 1777 17.32333333 20.21666667 0.222828586 Up 0.408956711 Gatc "glutamyl-tRNA(Gln) amidotransferase, subunit C" K02435|1|1e-81|306|mmu:384281|aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0032550;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor" GO:0006448//regulation of translational elongation;GO:0043039//tRNA aminoacylation "gi|148687917|gb|EDL19864.1|/6.67162e-83/RIKEN cDNA 2010003O18, partial [Mus musculus]" 12461 1962 58.15 66.18 0.1866161 Up 0.408919102 Cct2 "chaperonin containing Tcp1, subunit 2 (beta)" K09494|1|0.0|1011|mmu:12461|T-complex protein 1 subunit beta GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0032550;GO:0005515//protein binding GO:0051084//'de novo' posttranslational protein folding;GO:0035036//sperm-egg recognition;GO:0043623//cellular protein complex assembly gi|126521835|ref|NP_031662.2|/0/T-complex protein 1 subunit beta [Mus musculus] 67943 4492 8.733333333 10.48 0.263034406 Up 0.408909699 Mesdc2 mesoderm development candidate 2 K03032|1|1e-12|79.0|tsp:Tsp_04046|26S proteasome regulatory subunit N2 GO:0044464;GO:0016020//membrane GO:0070325//lipoprotein particle receptor binding GO:0007166//cell surface receptor signaling pathway;GO:0009888//tissue development;GO:0044267//cellular protein metabolic process;GO:0034613//cellular protein localization gi|26345650|dbj|BAC36476.1|/3.93305e-101/unnamed protein product [Mus musculus] 14082 2871 8.756666667 10.50666667 0.262851334 Up 0.408909699 Fadd Fas (TNFRSF6)-associated via death domain K02373|1|8e-84|314|mmu:14082|FAS-associated death domain protein GO:0044424;GO:0042995//cell projection;GO:0031264//death-inducing signaling complex GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0019899//enzyme binding GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0009612//response to mechanical stimulus;GO:0001819//positive regulation of cytokine production;GO:0051259//protein oligomerization;GO:0002252;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0006508//proteolysis;GO:0006952//defense response;GO:0097191//extrinsic apoptotic signaling pathway gi|6753812|ref|NP_034305.1|/7.00539e-83/FAS-associated death domain protein [Mus musculus] 66271 766 56.62 64.60666667 0.190371293 Up 0.40887209 Tmem126a transmembrane protein 126A K18157|1|6e-106|385|mmu:66271|transmembrane protein 126A GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0021545//cranial nerve development gi|13384870|ref|NP_079736.1|/4.82942e-105/transmembrane protein 126A [Mus musculus] 26372 5198 4.376666667 3.36 -0.381371277 Down 0.408806273 Clcn6 "chloride channel, voltage-sensitive 6" K05015|1|0.0|1517|mmu:26372|chloride channel 6 - - - - 105653 2789 9.973333333 11.9 0.254813899 Up 0.408787469 Phyhip phytanoyl-CoA hydroxylase interacting protein - - - - "gi|77046155|gb|AAH30494.2|/0/Phyhip protein, partial [Mus musculus]" 21374 1842 5.47 6.766666667 0.306904489 Up 0.408731054 Tbp TATA box binding protein K03120|1|9e-126|453|myd:102754954|transcription initiation factor TFIID TATA-box-binding protein GO:0000790//nuclear chromatin;GO:0005667//transcription factor complex;GO:0045120//pronucleus GO:0001085//RNA polymerase II transcription factor binding;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated" "gi|148688513|gb|EDL20460.1|/1.1001e-128/TATA box binding protein, isoform CRA_b, partial [Mus musculus]" 53313 4593 6.7 5.403333333 -0.310311411 Down 0.408731054 Atp2a3 "ATPase, Ca++ transporting, ubiquitous" "K05853|1|0.0|1998|mmu:53313|Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]" GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum GO:0043169//cation binding;GO:0032550;GO:0019829//cation-transporting ATPase activity;GO:0043169//cation binding;GO:0032550;GO:0019829//cation-transporting ATPase activity;GO:0043169//cation binding;GO:0032550;GO:0019829//cation-transporting ATPase activity GO:0070838//divalent metal ion transport;GO:0070838//divalent metal ion transport;GO:0070838//divalent metal ion transport gi|564372536|ref|XP_006246659.1|/0/PREDICTED: sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X1 [Rattus norvegicus] 20360 4087.86 1.113333333 1.773333333 0.671578143 Up 0.408665238 Sema6c "sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C" K06842|1|0.0|1355|mmu:20360|semaphorin 6 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005102//receptor binding;GO:0005102//receptor binding;GO:0005102//receptor binding;GO:0005102//receptor binding;GO:0005102//receptor binding GO:0006935//chemotaxis;GO:0048731//system development;GO:0048869//cellular developmental process;GO:0006935//chemotaxis;GO:0048731//system development;GO:0048869//cellular developmental process;GO:0006935//chemotaxis;GO:0048731//system development;GO:0048869//cellular developmental process;GO:0006935//chemotaxis;GO:0048731//system development;GO:0048869//cellular developmental process;GO:0006935//chemotaxis;GO:0048731//system development;GO:0048869//cellular developmental process "gi|148706836|gb|EDL38783.1|/0/sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C, isoform CRA_d, partial [Mus musculus]" 23938 2258 11.93666667 14.07666667 0.237905728 Up 0.408627628 Map2k5 mitogen-activated protein kinase kinase 5 K04463|1|0.0|906|mmu:23938|mitogen-activated protein kinase kinase 5 [EC:2.7.12.2] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0032550;GO:0043169//cation binding GO:0016525//negative regulation of angiogenesis;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016049//cell growth;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0042036//negative regulation of cytokine biosynthetic process;GO:0032682//negative regulation of chemokine production;GO:0070848//response to growth factor;GO:0034616//response to laminar fluid shear stress;GO:0006366//transcription from RNA polymerase II promoter;GO:0000165//MAPK cascade;GO:0034097//response to cytokine;GO:0010604;GO:0022408//negative regulation of cell-cell adhesion;GO:0006468//protein phosphorylation gi|6754624|ref|NP_035970.1|/0/dual specificity mitogen-activated protein kinase kinase 5 [Mus musculus] 21343 2264 22.48333333 26.07 0.21353464 Up 0.408618226 Taf6 TATA-box binding protein associated factor 6 K03131|1|0.0|978|phd:102333024|transcription initiation factor TFIID subunit 6 GO:0044665//MLL1/2 complex;GO:0005667//transcription factor complex GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding "GO:0051726//regulation of cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter" gi|984111083|ref|XP_015347001.1|/0/PREDICTED: transcription initiation factor TFIID subunit 6 isoform X1 [Marmota marmota marmota] 18133 2366 1.536666667 0.916666667 -0.745335132 Down 0.408608823 Nov nephroblastoma overexpressed gene K06827|1|1e-100|370|acs:100562863|connective tissue growth factor GO:0043227//membrane-bounded organelle;GO:0043005//neuron projection;GO:0044297//cell body GO:0005102//receptor binding;GO:0019838//growth factor binding GO:0016049//cell growth;GO:0010467//gene expression gi|6754876|ref|NP_035060.1|/0/protein NOV homolog precursor [Mus musculus] 14299 4036 3.213333333 4.2 0.386318682 Up 0.408580616 Ncs1 neuronal calcium sensor 1 K19932|1|4e-105|385|lcm:102350301|neuronal calcium sensor 1 GO:0000139//Golgi membrane;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0030141//secretory granule GO:0005262//calcium channel activity;GO:0046872//metal ion binding;GO:0004860//protein kinase inhibitor activity;GO:0019900//kinase binding GO:0048017//inositol lipid-mediated signaling;GO:0031175//neuron projection development;GO:0006887//exocytosis;GO:0007268//chemical synaptic transmission gi|9790115|ref|NP_062655.1|/3.63198e-104/neuronal calcium sensor 1 [Mus musculus] 20528 2822 246.91 279.8166667 0.180496628 Up 0.408524202 Slc2a4 "solute carrier family 2 (facilitated glucose transporter), member 4" "K07191|1|0.0|828|mmu:20528|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4" GO:0012506//vesicle membrane;GO:0030141//secretory granule;GO:0030135//coated vesicle;GO:0016021//integral component of membrane;GO:0005770//late endosome;GO:0009986//cell surface;GO:0005798//Golgi-associated vesicle;GO:0005886//plasma membrane GO:0005356;GO:0005488//binding GO:0032868//response to insulin;GO:0006818//hydrogen transport;GO:0033500//carbohydrate homeostasis;GO:0045444//fat cell differentiation;GO:0008645//hexose transport;GO:0006970//response to osmotic stress;GO:0009059//macromolecule biosynthetic process;GO:0097305//response to alcohol;GO:0006811//ion transport "gi|15679951|gb|AAH14282.1|/0/Solute carrier family 2 (facilitated glucose transporter), member 4 [Mus musculus]" 77951 2274 4.896666667 6.123333333 0.322517231 Up 0.40843958 Cyp20a1 "cytochrome P450, family 20, subfamily a, polypeptide 1" "K07435|1|0.0|845|mmu:77951|cytochrome P450, family 20, subfamily A" - - - - 241694 9633 8.706666667 7.186666667 -0.276797719 Down 0.408383166 Ralgapa2 "Ral GTPase activating protein, alpha subunit 2 (catalytic)" K07207|1|3e-22|112|crg:105344173|tuberous sclerosis 2 - - - - 225115 7424 35.84666667 31.10333333 -0.204769769 Down 0.408138704 Svil supervillin K10369|1|0.0|4275|mmu:225115|supervillin GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0016020//membrane GO:0003779//actin binding GO:0014706//striated muscle tissue development;GO:0006996//organelle organization gi|23346601|ref|NP_694793.1|/0/supervillin [Mus musculus] 27426 2185.58 8.79 10.52 0.259199634 Up 0.408072887 Nagpa N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase K01125|1|0.0|954|mmu:27426|N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase [EC:3.1.4.45] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity;GO:0003824//catalytic activity - "gi|148664864|gb|EDK97280.1|/0/N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, isoform CRA_b, partial [Mus musculus]" 382010 1433 2.08 2.9 0.479469372 Up 0.407772011 Cep44 centrosomal protein 44 K16761|1|0.0|760|mmu:382010|centrosomal protein CEP44 - - - - 23821 4178 13.54 11.43333333 -0.243981663 Down 0.407696792 Bace1 beta-site APP cleaving enzyme 1 K04521|1|0.0|984|mmu:23821|beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:3.4.23.46] GO:0043005//neuron projection;GO:0012506//vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0012506//vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0004175//endopeptidase activity;GO:0005515//protein binding GO:0019538//protein metabolic process;GO:0006518//peptide metabolic process;GO:0019538//protein metabolic process;GO:0006518//peptide metabolic process gi|225543122|ref|NP_001139419.1|/0/beta-secretase 1 isoform 2 precursor [Mus musculus] 71683 2198 17.38 20.20333333 0.21716526 Up 0.407640378 Gypc glycophorin C K06576|1|9e-35|151|mmu:71683|glycophorin C GO:0005856//cytoskeleton;GO:0031224//intrinsic component of membrane - - "gi|148664646|gb|EDK97062.1|/2.90211e-70/glycophorin C, partial [Mus musculus]" 16639 1105 0.596666667 0.173333333 -1.783376059 Down 0.407527549 Klra8 "killer cell lectin-like receptor, subfamily A, member 8" K10069|1|4e-16|88.2|myb:106725970|C-type lectin domain family 1 member A;K17517|2|6e-16|87.4|myb:102251819|C-type lectin domain family 12 member B;K10074|3|1e-15|86.7|ocu:100339146|C-type lectin domain family 7 member A;K17515|4|2e-15|85.9|cmy:102931345|C-type lectin domain family 9 member A GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding GO:0051707//response to other organism;GO:0022610;GO:0051707//response to other organism;GO:0022610 gi|197333718|ref|NP_001095090.1|/1.03728e-157/killer cell lectin-like receptor 8 isoform 1 [Mus musculus] 68089 2264.95 16.85333333 19.65333333 0.221740061 Up 0.407320697 Arpc4 "actin related protein 2/3 complex, subunit 4" "K05755|1|2e-71|248|cjc:100894431|actin related protein 2/3 complex, subunit 4" GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton GO:0003779//actin binding;GO:0003779//actin binding GO:0045010//actin nucleation;GO:0045010//actin nucleation;GO:0045010//actin nucleation "gi|148667043|gb|EDK99459.1|/6.51891e-49/actin related protein 2/3 complex, subunit 4, isoform CRA_b, partial [Mus musculus]" 56531 7050 4.123333333 3.14 -0.393046535 Down 0.407189063 Ylpm1 YLP motif containing 1 K17602|1|0.0|2328|mmu:56531|YLP motif-containing protein 1 - - - gi|146134507|ref|NP_848140.3|/0/YLP motif-containing protein 1 [Mus musculus] 73149 1328 0.976666667 1.606666667 0.718132482 Up 0.407170258 Clec4a3 "C-type lectin domain family 4, member a3" K10057|1|7e-132|473|mmu:73149|C-type lectin domain family 4 member A - - - "gi|148667286|gb|EDK99702.1|/1.69729e-139/C-type lectin domain family 4, member a3, isoform CRA_b, partial [Mus musculus]" 272359 2741 10.21 12.10333333 0.245421563 Up 0.407076235 Irf2bp1 interferon regulatory factor 2 binding protein 1 K04498|1|7e-106|387|chx:102187824|E1A/CREB-binding protein [EC:2.3.1.48];K11318|2|2e-42|177|ocu:103350931|ataxin-7;K11412|4|7e-26|122|aam:106491452|NAD-dependent deacetylase sirtuin 2 [EC:3.5.1.-] - - - - 407243 1700 31.25333333 35.83666667 0.197426383 Up 0.407076235 Tmem189 transmembrane protein 189 K10704|1|4e-144|514|mmu:407243|ubiquitin-conjugating enzyme E2 variant GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle "GO:0016879//ligase activity, forming carbon-nitrogen bonds" - gi|21704060|ref|NP_663513.1|/3.1665e-143/transmembrane protein 189 [Mus musculus] 70717 2876 7.616666667 6.21 -0.294566491 Down 0.406972808 Medag mesenteric estrogen dependent adipogenesis - GO:0044424 - GO:0045444//fat cell differentiation gi|27529947|dbj|BAC53804.1|/1.73389e-173/mAWMS3 [Mus musculus] 193003 3014 2.586666667 3.476666667 0.4266106 Up 0.406963406 Pirt phosphoinositide-interacting regulator of transient receptor potential channels - GO:0031224//intrinsic component of membrane - - gi|30520017|ref|NP_848771.1|/1.45554e-62/phosphoinositide-interacting protein [Mus musculus] 30050 2781.75 16.48 19.25666667 0.224641751 Up 0.406925796 Fbxw2 F-box and WD-40 domain protein 2 K10261|1|5e-128|461|mdo:100013249|F-box and WD-40 domain protein 2 GO:0044424;GO:0043231//intracellular membrane-bounded organelle;GO:0044424 - - gi|795342519|ref|XP_011782802.1|/0/PREDICTED: F-box/WD repeat-containing protein 2 isoform X2 [Colobus angolensis palliatus] 70601 3125 16.97333333 19.75333333 0.218826207 Up 0.406925796 Ecd ecdysoneless homolog (Drosophila) - GO:0043231//intracellular membrane-bounded organelle - "GO:1901990//regulation of mitotic cell cycle phase transition;GO:0006351//transcription, DNA-templated" gi|28076957|ref|NP_081751.1|/0/protein ecdysoneless homolog [Mus musculus] 50769 3685 1.106666667 0.563333333 -0.974159995 Down 0.406709542 Atp8a2 "ATPase, aminophospholipid transporter-like, class I, type 8A, member 2" K14802|1|0.0|2267|mmu:50769|phospholipid-transporting ATPase [EC:3.6.3.1] GO:0031224//intrinsic component of membrane GO:0032550;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0003824//catalytic activity GO:0050905//neuromuscular process;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0003009//skeletal muscle contraction;GO:0030030//cell projection organization;GO:0008544//epidermis development;GO:0035264//multicellular organism growth;GO:0006811//ion transport;GO:0006869//lipid transport;GO:0007631//feeding behavior gi|568988129|ref|XP_006519295.1|/0/PREDICTED: phospholipid-transporting ATPase IB isoform X2 [Mus musculus] 213053 4924.71 25.05666667 21.63 -0.212160838 Down 0.406549701 Slc39a14 "solute carrier family 39 (zinc transporter), member 14" "K14720|1|0.0|950|mmu:213053|solute carrier family 39 (zinc transporter), member 14" GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0005381//iron ion transmembrane transporter activity;GO:0005381//iron ion transmembrane transporter activity;GO:0005381//iron ion transmembrane transporter activity GO:0072503;GO:0071577//zinc II ion transmembrane transport;GO:0006826//iron ion transport;GO:0072503;GO:0071577//zinc II ion transmembrane transport;GO:0006826//iron ion transport;GO:0072503;GO:0071577//zinc II ion transmembrane transport;GO:0006826//iron ion transport "gi|148703960|gb|EDL35907.1|/0/solute carrier family 39 (zinc transporter), member 14, isoform CRA_b, partial [Mus musculus]" 76642 983 16.64333333 19.39333333 0.22061639 Up 0.406342849 1700113A16Rik RIKEN cDNA 1700113A16 gene - - - - - 192173 1286 29.78666667 34.27 0.202279507 Up 0.406314641 Fam195b "family with sequence similarity 195, member B" K17566|1|5e-17|91.3|gfr:102032806|protein phosphatase 1 regulatory subunit 27 - - - "gi|19344056|gb|AAH25536.1|/4.19116e-46/BC003940 protein, partial [Mus musculus]" 20382 1903 48.98333333 55.91666667 0.190987407 Up 0.406239422 Srsf2 serine/arginine-rich splicing factor 2 "K12891|1|6e-47|191|pon:100439801|splicing factor, arginine/serine-rich 2" GO:0016604//nuclear body GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding GO:0000377;GO:0006405//RNA export from nucleus;GO:0006397//mRNA processing;GO:0006366//transcription from RNA polymerase II promoter "gi|293675|gb|AAA39332.1|/1.62086e-91/IFN-response element binding factor 2, partial [Mus musculus]" 75812 2174.57 1.69 2.443333333 0.531827451 Up 0.40619241 Tasp1 "taspase, threonine aspartase 1" "K08657|1|2e-165|462|tgu:100222283|taspase, threonine aspartase, 1 [EC:3.4.25.-]" - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity "GO:0006351//transcription, DNA-templated;GO:0019538//protein metabolic process;GO:0006351//transcription, DNA-templated;GO:0019538//protein metabolic process;GO:0006351//transcription, DNA-templated;GO:0019538//protein metabolic process;GO:0006351//transcription, DNA-templated;GO:0019538//protein metabolic process" gi|940731734|ref|XP_014310608.1|/3.55595e-178/PREDICTED: threonine aspartase 1 isoform X2 [Myotis lucifugus] 20308 3008 7.64 9.216666667 0.270672436 Up 0.406145398 Ccl9 chemokine (C-C motif) ligand 9 K05510|1|1e-65|254|mmu:20308|C-C motif chemokine 6/9;K05511|4|2e-24|117|cge:100769898|C-C motif chemokine 15/23 GO:0044421 GO:0048020//CCR chemokine receptor binding;GO:0005125//cytokine activity GO:0006935//chemotaxis;GO:0002376//immune system process;GO:0012501//programmed cell death gi|6755434|ref|NP_035468.1|/1.18792e-64/C-C motif chemokine 9 precursor [Mus musculus] 106073 1742 13.27333333 15.61333333 0.234247855 Up 0.406079582 Mfsd5 major facilitator superfamily domain containing 5 - GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization gi|34364686|emb|CAE45795.1|/0/hypothetical protein [Homo sapiens] 73747 1501 21.42666667 24.82666667 0.212483144 Up 0.406070179 1110034G24Rik RIKEN cDNA 1110034G24 gene K19991|1|2e-59|232|aml:100482216|chromogranin-B - - - gi|755500651|ref|XP_011238100.1|/1.43968e-120/PREDICTED: uncharacterized protein C20orf196 homolog isoform X2 [Mus musculus] 15511 2810 1.49 0.883333333 -0.754282472 Down 0.406070179 Hspa1b heat shock protein 1B K03283|1|0.0|1134|mmu:15511|heat shock 70kDa protein 1/8 GO:0016234//inclusion body;GO:0016604//nuclear body;GO:0043234//protein complex;GO:0044459;GO:0044429 GO:0032550;GO:0044389//ubiquitin-like protein ligase binding;GO:0008134//transcription factor binding GO:0009605//response to external stimulus;GO:0006457//protein folding;GO:0006401//RNA catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0035966//response to topologically incorrect protein;GO:0008283//cell proliferation;GO:0019229//regulation of vasoconstriction;GO:0006259//DNA metabolic process;GO:0035036//sperm-egg recognition;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0030218//erythrocyte differentiation;GO:0016049//cell growth;GO:0051129 gi|124339826|ref|NP_034608.2|/0/heat shock 70 kDa protein 1B [Mus musculus] 21833 2442.58 49.56 56.43666667 0.187456593 Up 0.40603257 Thra thyroid hormone receptor alpha K05547|1|0.0|838|pale:102881243|thyroid hormone receptor alpha - - - - 69139 322 3.773333333 2.84 -0.409948623 Down 0.405863327 Ctrcos "chymotrypsin C (caldecrin), opposite strand" - - - - - 19355 2248.87 4.753333333 5.953333333 0.324758099 Up 0.405741096 Rad1 RAD1 checkpoint DNA exonuclease K02830|1|1e-159|565|mmu:19355|cell cycle checkpoint protein [EC:3.1.11.2] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0003677//DNA binding;GO:0016895//exodeoxyribonuclease activity, producing 5'-phosphomonoesters;GO:0003677//DNA binding;GO:0016895//exodeoxyribonuclease activity, producing 5'-phosphomonoesters;GO:0003677//DNA binding;GO:0016895//exodeoxyribonuclease activity, producing 5'-phosphomonoesters" GO:0006259//DNA metabolic process;GO:0010212//response to ionizing radiation;GO:0007127//meiosis I;GO:0006974//cellular response to DNA damage stimulus;GO:0006259//DNA metabolic process;GO:0010212//response to ionizing radiation;GO:0007127//meiosis I;GO:0006974//cellular response to DNA damage stimulus;GO:0006259//DNA metabolic process;GO:0010212//response to ionizing radiation;GO:0007127//meiosis I;GO:0006974//cellular response to DNA damage stimulus gi|84872189|ref|NP_035362.2|/8.37731e-159/cell cycle checkpoint protein RAD1 isoform 1 [Mus musculus] 56351 1954 30.44 34.86 0.195604211 Up 0.405694084 Ptges3 prostaglandin E synthase 3 (cytosolic) K15730|1|7e-87|324|ngi:103730212|cytosolic prostaglandin-E synthase [EC:5.3.99.3] GO:0031981//nuclear lumen;GO:0015629//actin cytoskeleton;GO:0044427;GO:0044297//cell body;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0030529//intracellular ribonucleoprotein complex GO:0003964//RNA-directed DNA polymerase activity;GO:0031072//heat shock protein binding;GO:0016860//intramolecular oxidoreductase activity GO:0008544//epidermis development;GO:0010467//gene expression;GO:0006693//prostaglandin metabolic process;GO:0005977//glycogen metabolic process;GO:0006259//DNA metabolic process;GO:0007600//sensory perception;GO:0008219//cell death;GO:0044767//single-organism developmental process;GO:0042026//protein refolding;GO:0031958 "gi|148692593|gb|EDL24540.1|/2.0506e-138/prostaglandin E synthase 3 (cytosolic), isoform CRA_b, partial [Mus musculus]" 14958 2304 55.82666667 49.10666667 -0.185035521 Down 0.40560006 H1f0 "H1 histone family, member 0" K11275|1|5e-47|161|nle:100601161|histone H1/5 - - - - 100034251 485 7.566666667 9.136666667 0.272010031 Up 0.405515439 Wfdc17 WAP four-disulfide core domain 17 K02599|1|5e-08|58.9|sko:100375670|Notch;K12864|2|8e-08|58.2|clv:102090334|beta-catenin-like protein 1 - - - "gi|148669730|gb|EDL01677.1|/1.75688e-47/mCG55370, partial [Mus musculus]" 228368 3114.31 5.343333333 6.603333333 0.305454455 Up 0.405477829 Slc35c1 "solute carrier family 35, member C1" "K15279|1|0.0|710|mmu:228368|solute carrier family 35 (GDP-fucose transporter), member C1" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0044765//single-organism transport;GO:0007219//Notch signaling pathway;GO:0051098//regulation of binding;GO:0030258//lipid modification;GO:0044765//single-organism transport;GO:0007219//Notch signaling pathway;GO:0051098//regulation of binding;GO:0030258//lipid modification gi|46877098|ref|NP_997597.1|/0/GDP-fucose transporter 1 isoform 1 [Mus musculus] 18537 1917 29.34333333 33.71333333 0.200286511 Up 0.405223965 Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 K00573|1|2e-147|525|mmu:18537|protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] - - - gi|821383403|ref|XP_012392277.1|/1.10973e-147/PREDICTED: protein-L-isoaspartate(D-aspartate) O-methyltransferase [Orcinus orca] 60363 1878 2.946666667 3.89 0.400686286 Up 0.40516755 Cldn15 claudin 15 K06087|1|1e-105|386|mmu:60363|claudin GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane - - gi|14149748|ref|NP_068365.1|/8.70091e-105/claudin-15 [Mus musculus] 100900 825 16.56666667 19.26 0.217324352 Up 0.40516755 Hscb HscB iron-sulfur cluster co-chaperone K04082|1|4e-122|439|mmu:100900|molecular chaperone HscB - - - - 331011 1483 1.506666667 2.223333333 0.561363989 Up 0.405092331 E330023G01Rik RIKEN cDNA E330023G01 gene - - - - - 20776 2437 0.906666667 1.513333333 0.739085646 Up 0.405064124 Tmie transmembrane inner ear - GO:0016020//membrane - GO:0042471//ear morphogenesis gi|26327771|dbj|BAC27626.1|/2.41146e-57/unnamed protein product [Mus musculus] 109711 3739 15.68333333 13.38 -0.229154106 Down 0.404894881 Actn1 "actinin, alpha 1" K05699|1|0.0|1805|mmu:109711|actinin alpha GO:0032432//actin filament bundle;GO:0005913//cell-cell adherens junction;GO:0031252//cell leading edge;GO:0031674//I band;GO:0030425//dendrite;GO:0031091//platelet alpha granule;GO:0005924//cell-substrate adherens junction;GO:0030667//secretory granule membrane GO:0005102//receptor binding;GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding GO:0007599//hemostasis;GO:0006928//movement of cell or subcellular component;GO:0006915//apoptotic process;GO:0006887//exocytosis;GO:0007044//cell-substrate junction assembly;GO:0007015//actin filament organization;GO:0001775//cell activation gi|61097906|ref|NP_598917.1|/0/alpha-actinin-1 [Mus musculus] 76582 4282 6.073333333 4.88 -0.315607406 Down 0.404753846 Ipo11 importin 11 K10393|1|1e-120|437|mgp:100538708|kinesin family member 2/24;K20224|2|2e-12|78.2|dvi:Dvir_GJ23426|importin-9;K18423|5|5e-11|73.6|ola:101170420|exportin-2 (importin alpha re-exporter) GO:0005635//nuclear envelope GO:0022892//substrate-specific transporter activity GO:0006606//protein import into nucleus gi|31541898|ref|NP_083941.2|/0/importin-11 [Mus musculus] 70750 2405.74 5.236666667 4.123333333 -0.34483768 Down 0.404688029 Kdsr 3-ketodihydrosphingosine reductase K04708|1|7e-133|475|mmu:70750|3-dehydrosphinganine reductase [EC:1.1.1.102] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0006665//sphingolipid metabolic process;GO:0042180//cellular ketone metabolic process;GO:0006665//sphingolipid metabolic process;GO:0042180//cellular ketone metabolic process gi|110625780|ref|NP_081810.1|/6.18794e-174/3-ketodihydrosphingosine reductase isoform 1 precursor [Mus musculus] 17095 1818 4.216666667 5.33 0.338032554 Up 0.404688029 Lyl1 lymphoblastomic leukemia 1 K15604|1|7e-149|530|mmu:17095|protein lyl-1 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0005515//protein binding "GO:0030098//lymphocyte differentiation;GO:0006351//transcription, DNA-templated;GO:0001568//blood vessel development" gi|113865989|ref|NP_032561.2|/6.11007e-148/protein lyl-1 [Mus musculus] 68250 1253 33.49666667 29.18666667 -0.198708083 Down 0.40461281 Fam96a "family with sequence similarity 96, member A" K11660|1|3e-25|118|tsp:Tsp_09343|metastasis-associated protein MTA GO:0044424 GO:0043169//cation binding GO:0044763 gi|847017943|ref|XP_012804702.1|/5.02533e-89/PREDICTED: MIP18 family protein FAM96A [Jaculus jaculus] 68888 793 0.51 0.12 -2.087462841 Down 0.40421791 Gkn3 gastrokine 3 - GO:0044421 - GO:0008285//negative regulation of cell proliferation gi|114326173|ref|NP_081136.1|/4.40555e-104/gastrokine-3 precursor [Mus musculus] 27998 1039 8.35 10.00333333 0.260632716 Up 0.404152093 Exosc5 exosome component 5 K12590|1|2e-108|394|mmu:27998|exosome complex component RRP46 GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006304//DNA modification;GO:0042254//ribosome biogenesis;GO:0002252;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006304//DNA modification;GO:0042254//ribosome biogenesis;GO:0002252;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" gi|20070392|ref|NP_613052.1|/1.80489e-107/exosome complex component RRP46 [Mus musculus] 217305 2440 1.25 1.916666667 0.61667136 Up 0.404105081 Cd300ld CD300 molecule like family member d K20395|1|3e-100|369|mmu:217305|CO300B/D/F antigen GO:0031224//intrinsic component of membrane - GO:0002573//myeloid leukocyte differentiation gi|21703872|ref|NP_663412.1|/2.58431e-99/CMRF35-like molecule 5 precursor [Mus musculus] 269587 5200.33 51.21333333 44.89666667 -0.189911126 Down 0.404086276 Epb41 erythrocyte membrane protein band 4.1 K06107|1|0.0|1471|mmu:269587|erythrocyte membrane protein band 4.1 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0044425;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0044425 GO:0008092//cytoskeletal protein binding;GO:0035091//phosphatidylinositol binding;GO:0008092//cytoskeletal protein binding;GO:0035091//phosphatidylinositol binding GO:0043393//regulation of protein binding;GO:0022604//regulation of cell morphogenesis;GO:0030036//actin cytoskeleton organization;GO:0043393//regulation of protein binding;GO:0022604//regulation of cell morphogenesis;GO:0030036//actin cytoskeleton organization gi|60360122|dbj|BAD90280.1|/0/mKIAA4056 protein [Mus musculus] 69129 1126 2.363333333 1.63 -0.535951162 Down 0.404048667 Pex11g peroxisomal biogenesis factor 11 gamma K13353|1|1e-122|441|mmu:69129|peroxin-11C GO:0031231//intrinsic component of peroxisomal membrane;GO:0032991//macromolecular complex - GO:0007031//peroxisome organization;GO:0032535//regulation of cellular component size gi|21735445|ref|NP_081227.1|/1.11876e-121/peroxisomal membrane protein 11C [Mus musculus] 100087 1556 11.21666667 13.22333333 0.237441893 Up 0.403964045 Kti12 "KTI12 homolog, chromatin associated" K15456|1|0.0|657|mmu:100087|protein KTI12 - - - - 18029 6282.66 50.42 44.15666667 -0.191364849 Down 0.403860619 Nfic nuclear factor I/C K09170|1|0.0|797|mmu:18029|nuclear factor I/C GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0044212//transcription regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0043566//structure-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0043566//structure-specific DNA binding GO:0042476//odontogenesis;GO:0006259//DNA metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0042476//odontogenesis;GO:0006259//DNA metabolic process;GO:0006366//transcription from RNA polymerase II promoter gi|84370351|ref|NP_081032.2|/0/nuclear factor 1 C-type isoform b [Mus musculus] 19012 1627.89 43.60666667 49.85 0.193044791 Up 0.403775998 Plpp1 phospholipid phosphatase 1 K01080|1|2e-164|581|mmu:19012|phosphatidate phosphatase [EC:3.1.3.4] - - - - 67269 4392.07 32.76333333 28.57666667 -0.197244501 Down 0.403691376 Agtpbp1 ATP/GTP binding protein 1 K04257|1|1e-18|99.0|shr:100920260|olfactory receptor;K05840|2|3e-18|97.8|myb:102243447|dopamine receptor D5 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0006996//organelle organization;GO:0043010//camera-type eye development;GO:0008344//adult locomotory behavior;GO:0021988//olfactory lobe development;GO:0021695//cerebellar cortex development;GO:0021533//cell differentiation in hindbrain;GO:0001505//regulation of neurotransmitter levels;GO:0018410;GO:0035608//protein deglutamylation;GO:0006996//organelle organization;GO:0043010//camera-type eye development;GO:0008344//adult locomotory behavior;GO:0021988//olfactory lobe development;GO:0021695//cerebellar cortex development;GO:0021533//cell differentiation in hindbrain;GO:0001505//regulation of neurotransmitter levels;GO:0018410;GO:0035608//protein deglutamylation;GO:0006996//organelle organization;GO:0043010//camera-type eye development;GO:0008344//adult locomotory behavior;GO:0021988//olfactory lobe development;GO:0021695//cerebellar cortex development;GO:0021533//cell differentiation in hindbrain;GO:0001505//regulation of neurotransmitter levels;GO:0018410;GO:0035608//protein deglutamylation;GO:0006996//organelle organization;GO:0043010//camera-type eye development;GO:0008344//adult locomotory behavior;GO:0021988//olfactory lobe development;GO:0021695//cerebellar cortex development;GO:0021533//cell differentiation in hindbrain;GO:0001505//regulation of neurotransmitter levels;GO:0018410;GO:0035608//protein deglutamylation;GO:0006996//organelle organization;GO:0043010//camera-type eye development;GO:0008344//adult locomotory behavior;GO:0021988//olfactory lobe development;GO:0021695//cerebellar cortex development;GO:0021533//cell differentiation in hindbrain;GO:0001505//regulation of neurotransmitter levels;GO:0018410;GO:0035608//protein deglutamylation gi|114158683|ref|NP_001041473.1|/0/cytosolic carboxypeptidase 1 isoform 2 [Mus musculus] 14083 4371.75 9.02 7.48 -0.270089163 Down 0.403681974 Ptk2 PTK2 protein tyrosine kinase 2 K05725|1|0.0|2002|mmu:14083|focal adhesion kinase 1 [EC:2.7.10.2] GO:0031252//cell leading edge;GO:0044459;GO:0044451;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0044291//cell-cell contact zone;GO:0005924//cell-substrate adherens junction;GO:0031252//cell leading edge;GO:0043232;GO:0044459;GO:0044451;GO:0044444//cytoplasmic part;GO:0044291//cell-cell contact zone;GO:0005924//cell-substrate adherens junction GO:0004713//protein tyrosine kinase activity;GO:0060089;GO:0005102//receptor binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding;GO:0019901//protein kinase binding;GO:0004713//protein tyrosine kinase activity;GO:0060089;GO:0005102//receptor binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding;GO:0019901//protein kinase binding GO:0035265//organ growth;GO:0007010//cytoskeleton organization;GO:0008284//positive regulation of cell proliferation;GO:0007162//negative regulation of cell adhesion;GO:0007416//synapse assembly;GO:0007268//chemical synaptic transmission;GO:0043062//extracellular structure organization;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0051647//nucleus localization;GO:0042311//vasodilation;GO:0016049//cell growth;GO:0031398//positive regulation of protein ubiquitination;GO:0007409//axonogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0001649//osteoblast differentiation;GO:0009605//response to external stimulus;GO:0030320//cellular monovalent inorganic anion homeostasis;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0051403//stress-activated MAPK cascade;GO:0043627//response to estrogen;GO:0022604//regulation of cell morphogenesis;GO:0009746;GO:0014909//smooth muscle cell migration;GO:0043066//negative regulation of apoptotic process;GO:0001944//vasculature development;GO:0006909//phagocytosis;GO:0035265//organ growth;GO:0007010//cytoskeleton organization;GO:0008284//positive regulation of cell proliferation;GO:0007162//negative regulation of cell adhesion;GO:0007416//synapse assembly;GO:0007268//chemical synaptic transmission;GO:0043062//extracellular structure organization;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0051647//nucleus localization;GO:0042311//vasodilation;GO:0016049//cell growth;GO:0031398//positive regulation of protein ubiquitination;GO:0007409//axonogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0001649//osteoblast differentiation;GO:0030320//cellular monovalent inorganic anion homeostasis;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0051403//stress-activated MAPK cascade;GO:0022604//regulation of cell morphogenesis;GO:0014909//smooth muscle cell migration;GO:0043066//negative regulation of apoptotic process;GO:0001944//vasculature development;GO:0006909//phagocytosis gi|568991341|ref|XP_006520495.1|/0/PREDICTED: focal adhesion kinase 1 isoform X9 [Mus musculus] 18640 6166.45 12.87 10.87333333 -0.243217772 Down 0.403672571 Pfkfb2 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2" "K19029|1|0.0|1049|mmu:18640|6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 2 [EC:2.7.1.105 3.1.3.46]" GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0032550;GO:0008443//phosphofructokinase activity;GO:0050308//sugar-phosphatase activity;GO:0019900//kinase binding;GO:0032550;GO:0008443//phosphofructokinase activity;GO:0050308//sugar-phosphatase activity;GO:0019900//kinase binding;GO:0032550;GO:0008443//phosphofructokinase activity;GO:0050308//sugar-phosphatase activity;GO:0019900//kinase binding;GO:0032550;GO:0008443//phosphofructokinase activity;GO:0050308//sugar-phosphatase activity;GO:0019900//kinase binding GO:0006007//glucose catabolic process;GO:0050796//regulation of insulin secretion;GO:0032787//monocarboxylic acid metabolic process;GO:0009746;GO:0033131;GO:0006007//glucose catabolic process;GO:0050796//regulation of insulin secretion;GO:0032787//monocarboxylic acid metabolic process;GO:0009746;GO:0033131;GO:0006007//glucose catabolic process;GO:0050796//regulation of insulin secretion;GO:0032787//monocarboxylic acid metabolic process;GO:0009746;GO:0033131;GO:0006007//glucose catabolic process;GO:0050796//regulation of insulin secretion;GO:0032787//monocarboxylic acid metabolic process;GO:0009746;GO:0033131 "gi|241666427|ref|NP_001155887.1|/0/6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform 2 [Mus musculus]" 72772 3344 4.036666667 3.083333333 -0.388673594 Down 0.403606755 Rint1 RAD50 interactor 1 K20474|1|0.0|1527|mmu:72772|RAD50-interacting protein 1 GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0000077//DNA damage checkpoint;GO:0045184//establishment of protein localization;GO:0006810//transport;GO:0000077//DNA damage checkpoint;GO:0045184//establishment of protein localization;GO:0006810//transport gi|62899067|ref|NP_796297.2|/0/RAD50-interacting protein 1 isoform 1 [Mus musculus] 226178 3898.83 43.57333333 49.77 0.191830904 Up 0.403578548 Wbp1l WW domain binding protein 1 like - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148710066|gb|EDL42012.1|/4.04512e-169/DNA segment, Chr 19, Wayne State University 162, expressed, isoform CRA_a, partial [Mus musculus]" 76308 1835 116.55 131.7533333 0.176890458 Up 0.403503328 Rab1b "RAB1B, member RAS oncogene family" K07875|1|2e-107|392|ngi:103725021|Ras-related protein Rab-1B GO:0043231//intracellular membrane-bounded organelle GO:0032550 GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization gi|664703871|ref|XP_008531408.1|/1.38887e-115/PREDICTED: ras-related protein Rab-1B [Equus przewalskii] 19302 2045.45 9.513333333 11.31666667 0.25042624 Up 0.40335289 Pex2 peroxisomal biogenesis factor 2 K06664|1|0.0|636|mmu:19302|peroxin-2 GO:0008023//transcription elongation factor complex;GO:0031231//intrinsic component of peroxisomal membrane;GO:0008023//transcription elongation factor complex;GO:0031231//intrinsic component of peroxisomal membrane;GO:0008023//transcription elongation factor complex;GO:0031231//intrinsic component of peroxisomal membrane;GO:0008023//transcription elongation factor complex;GO:0031231//intrinsic component of peroxisomal membrane;GO:0008023//transcription elongation factor complex;GO:0031231//intrinsic component of peroxisomal membrane;GO:0008023//transcription elongation factor complex;GO:0031231//intrinsic component of peroxisomal membrane;GO:0008023//transcription elongation factor complex;GO:0031231//intrinsic component of peroxisomal membrane GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0009062//fatty acid catabolic process;GO:0008285//negative regulation of cell proliferation;GO:0006695//cholesterol biosynthetic process;GO:0006625//protein targeting to peroxisome;GO:0016477//cell migration;GO:0055092//sterol homeostasis;GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0009062//fatty acid catabolic process;GO:0008285//negative regulation of cell proliferation;GO:0006695//cholesterol biosynthetic process;GO:0006625//protein targeting to peroxisome;GO:0016477//cell migration;GO:0055092//sterol homeostasis;GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0009062//fatty acid catabolic process;GO:0008285//negative regulation of cell proliferation;GO:0006695//cholesterol biosynthetic process;GO:0006625//protein targeting to peroxisome;GO:0016477//cell migration;GO:0055092//sterol homeostasis;GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0009062//fatty acid catabolic process;GO:0008285//negative regulation of cell proliferation;GO:0006695//cholesterol biosynthetic process;GO:0006625//protein targeting to peroxisome;GO:0016477//cell migration;GO:0055092//sterol homeostasis;GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0009062//fatty acid catabolic process;GO:0008285//negative regulation of cell proliferation;GO:0006695//cholesterol biosynthetic process;GO:0006625//protein targeting to peroxisome;GO:0016477//cell migration;GO:0055092//sterol homeostasis;GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0009062//fatty acid catabolic process;GO:0008285//negative regulation of cell proliferation;GO:0006695//cholesterol biosynthetic process;GO:0006625//protein targeting to peroxisome;GO:0016477//cell migration;GO:0055092//sterol homeostasis;GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0009062//fatty acid catabolic process;GO:0008285//negative regulation of cell proliferation;GO:0006695//cholesterol biosynthetic process;GO:0006625//protein targeting to peroxisome;GO:0016477//cell migration;GO:0055092//sterol homeostasis "gi|148673269|gb|EDL05216.1|/0/peroxisomal membrane protein 3, isoform CRA_b, partial [Mus musculus]" 13170 1678 27.65 31.79333333 0.201444802 Up 0.403230659 Dbp D site albumin promoter binding protein K09056|1|3e-117|424|mmu:13170|albumin D box-binding protein GO:0043231//intracellular membrane-bounded organelle "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000976//transcription regulatory region sequence-specific DNA binding" GO:0048511//rhythmic process;GO:0044767//single-organism developmental process;GO:0006366//transcription from RNA polymerase II promoter gi|170650717|ref|NP_058670.2|/2.49094e-116/D site-binding protein [Mus musculus] 17380 5722 1.476666667 0.876666667 -0.752243899 Down 0.403230659 Mme membrane metallo endopeptidase K01389|1|0.0|1379|mmu:17380|neprilysin [EC:3.4.24.11] GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0033218//amide binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0033218//amide binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0033218//amide binding GO:0006518//peptide metabolic process;GO:0010224//response to UV-B;GO:0007600//sensory perception;GO:0072338;GO:0019538//protein metabolic process;GO:0034644//cellular response to UV;GO:0007569//cell aging;GO:0034097//response to cytokine;GO:0006518//peptide metabolic process;GO:0010224//response to UV-B;GO:0007600//sensory perception;GO:0072338;GO:0019538//protein metabolic process;GO:0034644//cellular response to UV;GO:0007569//cell aging;GO:0034097//response to cytokine;GO:0006518//peptide metabolic process;GO:0010224//response to UV-B;GO:0007600//sensory perception;GO:0072338;GO:0019538//protein metabolic process;GO:0034644//cellular response to UV;GO:0007569//cell aging;GO:0034097//response to cytokine "gi|148703442|gb|EDL35389.1|/0/membrane metallo endopeptidase, isoform CRA_a, partial [Mus musculus]" 93686 5846.65 15.75666667 18.35 0.219817699 Up 0.403164843 Rbfox2 "RNA binding protein, fox-1 homolog (C. elegans) 2" K14946|1|3e-128|463|pss:102458424|RNA binding protein fox-1 GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0003723//RNA binding "GO:0016358//dendrite development;GO:0006351//transcription, DNA-templated;GO:0021932;GO:0045646//regulation of erythrocyte differentiation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0050905//neuromuscular process;GO:0016358//dendrite development;GO:0006351//transcription, DNA-templated;GO:0021932;GO:0045646//regulation of erythrocyte differentiation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0050905//neuromuscular process;GO:0016358//dendrite development;GO:0006351//transcription, DNA-templated;GO:0021932;GO:0045646//regulation of erythrocyte differentiation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0050905//neuromuscular process;GO:0016358//dendrite development;GO:0006351//transcription, DNA-templated;GO:0021932;GO:0045646//regulation of erythrocyte differentiation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0050905//neuromuscular process;GO:0016358//dendrite development;GO:0006351//transcription, DNA-templated;GO:0021932;GO:0045646//regulation of erythrocyte differentiation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0050905//neuromuscular process;GO:0016358//dendrite development;GO:0006351//transcription, DNA-templated;GO:0021932;GO:0045646//regulation of erythrocyte differentiation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0050905//neuromuscular process;GO:0016358//dendrite development;GO:0006351//transcription, DNA-templated;GO:0021932;GO:0045646//regulation of erythrocyte differentiation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0050905//neuromuscular process;GO:0016358//dendrite development;GO:0006351//transcription, DNA-templated;GO:0021932;GO:0045646//regulation of erythrocyte differentiation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0050905//neuromuscular process;GO:0016358//dendrite development;GO:0006351//transcription, DNA-templated;GO:0021932;GO:0045646//regulation of erythrocyte differentiation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0050905//neuromuscular process" gi|568993691|ref|XP_006521632.1|/0/PREDICTED: RNA binding protein fox-1 homolog 2 isoform X6 [Mus musculus] 56335 2035 8.136666667 9.763333333 0.262935898 Up 0.403108428 Mettl3 methyltransferase like 3 K05925|1|0.0|1060|mmu:56335|mRNA (2'-O-methyladenosine-N6-)-methyltransferase [EC:2.1.1.62] GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0008174//mRNA methyltransferase activity GO:0001510//RNA methylation gi|537258903|gb|ERE89584.1|/0/sal-like protein 2 [Cricetulus griseus] 319653 2766 2.293333333 3.123333333 0.445640483 Up 0.402901576 Slc25a40 "solute carrier family 25, member 40" "K15119|1|0.0|655|mmu:319653|solute carrier family 25, member 39/40" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763 "gi|148682724|gb|EDL14671.1|/6.91741e-168/RIKEN cDNA B230315F11, isoform CRA_b, partial [Mus musculus]" 80861 2427 2.26 3.086666667 0.44972692 Up 0.402901576 Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 K12649|1|0.0|1321|mmu:80861|ATP-dependent RNA helicase DHX58 [EC:3.6.3.14] GO:0044424 GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0003723//RNA binding;GO:0046914//transition metal ion binding GO:0039529//RIG-I signaling pathway;GO:0031348//negative regulation of defense response;GO:0001818//negative regulation of cytokine production;GO:0039530//MDA-5 signaling pathway gi|70608133|ref|NP_084426.2|/0/probable ATP-dependent RNA helicase DHX58 [Mus musculus] 664787 1205 0.05 0.39 2.963474124 Up 0.402788747 LOC664787 Sp110 nuclear body protein pseudogene - - - - - 105559 4525 31.48 27.38666667 -0.20096186 Down 0.402741735 Mbnl2 muscleblind-like 2 K14943|1|1e-163|512|ocu:100356041|muscleblind - - - gi|402902332|ref|XP_003914061.1|/0/PREDICTED: muscleblind-like protein 2 isoform X2 [Papio anubis] 69666 501 15.04 12.81 -0.231534091 Down 0.402741735 Psmg4 "proteasome (prosome, macropain) assembly chaperone 4" K11878|1|1e-28|127|mmu:69666|proteasome assembly chaperone 4 - - - gi|160333436|ref|NP_001103985.1|/7.75905e-41/proteasome assembly chaperone 4 isoform a [Mus musculus] 12053 3326 6.713333333 5.436666667 -0.304306901 Down 0.402619504 Bcl6 B cell leukemia/lymphoma 6 K15618|1|0.0|1405|mmu:12053|B-cell lymphoma 6 protein GO:0031981//nuclear lumen;GO:0044427 GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0046914//transition metal ion binding GO:0006954//inflammatory response;GO:0001952//regulation of cell-matrix adhesion;GO:0006915//apoptotic process;GO:0007010//cytoskeleton organization;GO:0032989;GO:0048232//male gamete generation;GO:0045064//T-helper 2 cell differentiation;GO:0016049//cell growth;GO:0045829;GO:0006606//protein import into nucleus;GO:0030888//regulation of B cell proliferation;GO:0033554//cellular response to stress;GO:0006366//transcription from RNA polymerase II promoter;GO:0002719;GO:0006928//movement of cell or subcellular component;GO:0002828//regulation of type 2 immune response;GO:0007266//Rho protein signal transduction;GO:0030218//erythrocyte differentiation gi|6753172|ref|NP_033874.1|/0/B-cell lymphoma 6 protein homolog [Mus musculus] 20336 3723 9.726666667 8.11 -0.262243563 Down 0.4026007 Exoc4 exocyst complex component 4 K06111|1|0.0|1886|mmu:20336|exocyst complex component 4 GO:0044327//dendritic spine head;GO:0043231//intracellular membrane-bounded organelle;GO:0030426//growth cone;GO:0044297//cell body;GO:0043209//myelin sheath;GO:0043234//protein complex GO:0019904//protein domain specific binding GO:0007267//cell-cell signaling;GO:0007163//establishment or maintenance of cell polarity;GO:0007417//central nervous system development;GO:0016482//cytosolic transport;GO:0006605//protein targeting;GO:0006887//exocytosis;GO:0044085;GO:0019722//calcium-mediated signaling gi|50511055|dbj|BAD32513.1|/0/mKIAA1699 protein [Mus musculus] 330544 3708 7.36 6.013333333 -0.291540834 Down 0.402581895 C230091D08Rik RIKEN cDNA C230091D08 gene - - - - - 59004 1676 12.95 15.17333333 0.228585959 Up 0.402487871 Pias4 protein inhibitor of activated STAT 4 K16065|1|0.0|913|mmu:59004|E3 SUMO-protein ligase PIAS4 GO:0034399//nuclear periphery;GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0019787//ubiquitin-like protein transferase activity GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0016925//protein sumoylation;GO:0032502//developmental process gi|124249349|ref|NP_067476.2|/0/E3 SUMO-protein ligase PIAS4 [Mus musculus] 15200 2392 15.3 13.08 -0.226169112 Down 0.402487871 Hbegf heparin-binding EGF-like growth factor K08523|1|8e-95|350|mmu:15200|heparin-binding EGF-like growth factor GO:0044464;GO:0016021//integral component of membrane;GO:0044421 GO:0070851//growth factor receptor binding;GO:0005539//glycosaminoglycan binding "GO:0048731//system development;GO:0038127//ERBB signaling pathway;GO:0044057;GO:0001824//blastocyst development;GO:0008284//positive regulation of cell proliferation;GO:0044319//wound healing, spreading of cells;GO:0010561;GO:0016049//cell growth;GO:0030335//positive regulation of cell migration" gi|6754178|ref|NP_034545.1|/7.10691e-94/proheparin-binding EGF-like growth factor precursor [Mus musculus] 17772 3368 2.876666667 3.8 0.40160136 Up 0.402422054 Mtm1 X-linked myotubular myopathy gene 1 K01108|1|4e-75|283|mmu:17772|myotubularin [EC:3.1.3.64 3.1.3.95] GO:0031252//cell leading edge;GO:0005768//endosome;GO:0042995//cell projection;GO:0016020//membrane;GO:0030017//sarcomere;GO:0031252//cell leading edge;GO:0005768//endosome;GO:0042995//cell projection;GO:0016020//membrane;GO:0030017//sarcomere;GO:0031252//cell leading edge;GO:0005768//endosome;GO:0042995//cell projection;GO:0016020//membrane;GO:0030017//sarcomere;GO:0031252//cell leading edge;GO:0005768//endosome;GO:0042995//cell projection;GO:0016020//membrane;GO:0030017//sarcomere;GO:0005768//endosome;GO:0042995//cell projection;GO:0016020//membrane;GO:0030017//sarcomere GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0052744//phosphatidylinositol monophosphate phosphatase activity;GO:0005543//phospholipid binding;GO:0032403//protein complex binding;GO:0004721//phosphoprotein phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0052744//phosphatidylinositol monophosphate phosphatase activity;GO:0005543//phospholipid binding;GO:0032403//protein complex binding;GO:0004721//phosphoprotein phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0052744//phosphatidylinositol monophosphate phosphatase activity;GO:0005543//phospholipid binding;GO:0032403//protein complex binding;GO:0004721//phosphoprotein phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0052744//phosphatidylinositol monophosphate phosphatase activity;GO:0005543//phospholipid binding;GO:0032403//protein complex binding;GO:0004721//phosphoprotein phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0052744//phosphatidylinositol monophosphate phosphatase activity;GO:0005543//phospholipid binding;GO:0032403//protein complex binding;GO:0004721//phosphoprotein phosphatase activity GO:0006470//protein dephosphorylation;GO:0007041//lysosomal transport;GO:0046488//phosphatidylinositol metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0045184//establishment of protein localization;GO:0019725//cellular homeostasis;GO:0007005//mitochondrion organization;GO:0045104//intermediate filament cytoskeleton organization;GO:0007033//vacuole organization;GO:0006470//protein dephosphorylation;GO:0007041//lysosomal transport;GO:0046488//phosphatidylinositol metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0045184//establishment of protein localization;GO:0019725//cellular homeostasis;GO:0007005//mitochondrion organization;GO:0045104//intermediate filament cytoskeleton organization;GO:0007033//vacuole organization;GO:0006470//protein dephosphorylation;GO:0007041//lysosomal transport;GO:0046488//phosphatidylinositol metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0045184//establishment of protein localization;GO:0019725//cellular homeostasis;GO:0007005//mitochondrion organization;GO:0045104//intermediate filament cytoskeleton organization;GO:0007033//vacuole organization;GO:0006470//protein dephosphorylation;GO:0007041//lysosomal transport;GO:0046488//phosphatidylinositol metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0045184//establishment of protein localization;GO:0019725//cellular homeostasis;GO:0007005//mitochondrion organization;GO:0045104//intermediate filament cytoskeleton organization;GO:0007033//vacuole organization;GO:0006470//protein dephosphorylation;GO:0007041//lysosomal transport;GO:0046488//phosphatidylinositol metabolic process;GO:0045184//establishment of protein localization;GO:0019725//cellular homeostasis;GO:0007005//mitochondrion organization;GO:0045104//intermediate filament cytoskeleton organization;GO:0007033//vacuole organization "gi|148694636|gb|EDL26583.1|/0/X-linked myotubular myopathy gene 1, isoform CRA_a, partial [Mus musculus]" 228715 459 27.08333333 31.12 0.200436748 Up 0.40236564 Gm561 predicted gene 561 - GO:0043231//intracellular membrane-bounded organelle - - gi|85701806|ref|NP_001028469.1|/7.7873e-56/uncharacterized protein LOC228715 [Mus musculus] 433693 1729 26.45 30.48666667 0.204910696 Up 0.40236564 Akirin2 akirin 2 - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005488//binding GO:0010952//positive regulation of peptidase activity;GO:0007275//multicellular organism development;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0001819//positive regulation of cytokine production;GO:0002237//response to molecule of bacterial origin gi|86604728|ref|NP_001007590.2|/1.17749e-68/akirin-2 [Mus musculus] 71004 1861 0.263333333 0.706666667 1.424139706 Up 0.40216819 4931440P22Rik RIKEN cDNA 4931440P22 gene - - - - gi|74206689|dbj|BAE41596.1|/1.88856e-35/unnamed protein product [Mus musculus] 66126 1091 15.47666667 18.01 0.218703401 Up 0.401989545 Elof1 "ELF1 homolog, elongation factor 1" K13617|1|3e-23|111|nvi:100121028|protein phosphatase methylesterase 1 [EC:3.1.1.89] - - - - 14547 2934 4.6 3.58 -0.361674274 Down 0.401980142 Gdap2 ganglioside-induced differentiation-associated-protein 2 K15212|1|8e-21|105|bfo:BRAFLDRAFT_123909|TATA box-binding protein-associated factor RNA polymerase I subunit A;K18470|2|3e-17|93.6|crg:105326503|Rho GTPase-activating protein 1 - - GO:0033993//response to lipid;GO:0033993//response to lipid gi|22094097|ref|NP_034399.1|/0/ganglioside-induced differentiation-associated protein 2 [Mus musculus] 52685 2530.68 92.97 105.6833333 0.184910715 Up 0.401980142 Cd300lg CD300 molecule like family member G K16663|1|1e-137|493|mmu:52685|CMRF35-like molecule 9 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148702135|gb|EDL34082.1|/0/CD300 antigen like family member G, isoform CRA_b, partial [Mus musculus]" 108014 1187.91 7.39 8.9 0.268230972 Up 0.401951935 Srsf9 serine/arginine-rich splicing factor 9 "K12890|1|1e-111|405|mmu:108014|splicing factor, arginine/serine-rich 1/9" GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding GO:0000245//spliceosomal complex assembly;GO:0006405//RNA export from nucleus;GO:0006366//transcription from RNA polymerase II promoter;GO:0000245//spliceosomal complex assembly;GO:0006405//RNA export from nucleus;GO:0006366//transcription from RNA polymerase II promoter gi|13385016|ref|NP_079849.1|/7.96744e-111/serine/arginine-rich splicing factor 9 [Mus musculus] 319601 2212 3.83 4.88 0.349536756 Up 0.401895521 Zfp653 zinc finger protein 653 K04961|1|8e-41|171|ocu:103351584|ryanodine receptor 1;K04405|2|2e-25|120|phi:102107277|evolutionarily conserved signaling intermediate in Toll pathway;K09228|4|7e-24|115|bfo:BRAFLDRAFT_124172|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|894216209|ref|NP_001297688.1|/0/zinc finger protein 653 isoform 1 [Mus musculus] 23830 2877 2.33 3.166666667 0.442635058 Up 0.401848509 Capn10 calpain 10 K08579|1|0.0|1349|mmu:23830|calpain-10 [EC:3.4.22.-] GO:0031966//mitochondrial membrane;GO:0019866//organelle inner membrane;GO:0043232 GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding GO:0032868//response to insulin;GO:0006915//apoptotic process;GO:0050796//regulation of insulin secretion;GO:0030036//actin cytoskeleton organization;GO:0009746;GO:0032386//regulation of intracellular transport;GO:0009991//response to extracellular stimulus;GO:0010828//positive regulation of glucose transport;GO:0044767//single-organism developmental process;GO:0019538//protein metabolic process gi|87080823|ref|NP_035926.2|/0/calpain-10 [Mus musculus] 68183 1422 26.81 30.78666667 0.199534453 Up 0.401829704 Bcas2 breast carcinoma amplified sequence 2 K12861|1|3e-120|434|ocu:100345435|pre-mRNA-splicing factor SPF27 GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen GO:0005488//binding GO:0008380//RNA splicing gi|640778806|ref|XP_008063201.1|/1.92033e-119/PREDICTED: pre-mRNA-splicing factor SPF27 [Tarsius syrichta] 18948 888 0.41 0.886666667 1.11276793 Up 0.40177329 Pnmt phenylethanolamine-N-methyltransferase K00553|1|2e-163|576|mmu:18948|phenylethanolamine N-methyltransferase [EC:2.1.1.28] GO:0044424;GO:0043025//neuronal cell body;GO:0033267 GO:0008170//N-methyltransferase activity GO:0070848//response to growth factor;GO:0051705;GO:0071385//cellular response to glucocorticoid stimulus;GO:0042414//epinephrine metabolic process;GO:0043434//response to peptide hormone;GO:0006790//sulfur compound metabolic process;GO:0097305//response to alcohol;GO:0006950//response to stress;GO:0035270//endocrine system development;GO:0007606//sensory perception of chemical stimulus gi|6679405|ref|NP_032916.1|/1.9632e-162/phenylethanolamine N-methyltransferase [Mus musculus] 22059 1781 11 12.95 0.235448574 Up 0.40173568 Trp53 transformation related protein 53 K04451|1|0.0|761|mmu:22059|tumor protein p53 - - - "gi|148678558|gb|EDL10505.1|/0/transformation related protein 53, isoform CRA_a, partial [Mus musculus]" 20167 1085.14 92.79 105.14 0.180270401 Up 0.401698071 Rtn2 reticulon 2 (Z-band associated protein) K19790|1|2e-53|213|hgl:101707732|protein phosphatase 1N [EC:3.1.3.16];K08288|2|2e-45|186|chx:102186405|protein kinase C substrate 80K-H;K09029|3|3e-18|96.3|fpg:101920606|protein FosB GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0060089;GO:0005488//binding GO:0007154//cell communication gi|70778920|ref|NP_001020535.1|/3.26706e-107/reticulon-2 isoform C [Mus musculus] 67847 3674.92 4.376666667 3.39 -0.368547237 Down 0.401688668 Sncaip "synuclein, alpha interacting protein (synphilin)" "K04558|1|0.0|1620|mmu:67847|synuclein, alpha interacting protein (synphilin)" - GO:0044389//ubiquitin-like protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding GO:0044087;GO:0007269//neurotransmitter secretion;GO:0006584//catecholamine metabolic process;GO:0044087;GO:0007269//neurotransmitter secretion;GO:0006584//catecholamine metabolic process;GO:0044087;GO:0007269//neurotransmitter secretion;GO:0006584//catecholamine metabolic process;GO:0044087;GO:0007269//neurotransmitter secretion;GO:0006584//catecholamine metabolic process gi|312434002|ref|NP_001186080.1|/0/synphilin-1 isoform 1 [Mus musculus] 207175 1059 0.1 0.483333333 2.273018494 Up 0.401679266 Cetn4 centrin 4 K16465|1|2e-65|251|oaa:100085756|centrin-1 GO:0005813//centrosome "GO:0046872//metal ion binding;GO:0032403//protein complex binding;GO:0042623//ATPase activity, coupled;GO:0032550" - gi|22003866|ref|NP_665824.1|/1.25485e-87/centrin-4 [Mus musculus] 625237 1170 30.91 26.94666667 -0.197966833 Down 0.401641656 Gm6566 predicted gene 6566 - - - - "gi|148670981|gb|EDL02928.1|/1.12835e-55/mCG145881, partial [Mus musculus]" 140917 4309 1.883333333 2.653333333 0.494517563 Up 0.401528828 Dclre1b DNA cross-link repair 1B K15341|1|0.0|857|mmu:140917|DNA cross-link repair 1B protein [EC:3.1.-.-] - - - - 327747 1529 0.23 0.663333333 1.528100164 Up 0.401481816 Mettl24 methyltransferase like 24 K12816|1|4e-34|148|bfo:BRAFLDRAFT_125902|pre-mRNA-processing factor 17 - GO:0016741 GO:0008152//metabolic process gi|29244322|ref|NP_808461.1|/0/methyltransferase-like protein 24 precursor [Mus musculus] 23890 1898 0.806666667 0.346666667 -1.218423519 Down 0.401425401 Gpr34 G protein-coupled receptor 34 K08383|1|0.0|754|mmu:23890|G protein-coupled receptor 34 - - - - 109900 1589 3.22 4.176666667 0.37529132 Up 0.401406597 Asl argininosuccinate lyase K01755|1|0.0|915|mmu:109900|argininosuccinate lyase [EC:4.3.2.1] GO:0043005//neuron projection;GO:0031966//mitochondrial membrane;GO:0043025//neuronal cell body GO:0016842 GO:0006575//cellular modified amino acid metabolic process;GO:0006526//arginine biosynthetic process;GO:0006473//protein acetylation;GO:0044767//single-organism developmental process;GO:0019627//urea metabolic process;GO:0006536//glutamate metabolic process;GO:0044708//single-organism behavior;GO:0007275//multicellular organism development gi|19526986|ref|NP_598529.1|/0/argininosuccinate lyase [Mus musculus] 66487 532.35 14.63 12.45 -0.232784027 Down 0.401274963 Smim4 small integral membrane protein 4 - - - - gi|818213457|ref|NP_001295393.1|/8.70953e-51/small integral membrane protein 4 isoform 1 [Mus musculus] 66158 1276 90.10666667 102.01 0.179004831 Up 0.401246756 Cxx1a CAAX box 1A - - - - gi|21313590|ref|NP_077132.1|/1.33087e-52/mammalian retrotransposon derived 8b [Mus musculus] 100090 2226 2.223333333 3.04 0.451347063 Up 0.401199744 Zbtb48 zinc finger and BTB domain containing 48 K10519|1|0.0|1385|mmu:100090|zinc finger and BTB domain-containing protein 48 GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated" gi|126366001|ref|NP_598640.2|/0/zinc finger and BTB domain-containing protein 48 [Mus musculus] 243764 2036 3.073333333 2.253333333 -0.447743504 Down 0.401199744 Chrm2 "cholinergic receptor, muscarinic 2, cardiac" K04130|1|0.0|876|mmu:243764|muscarinic acetylcholine receptor M2 - - - - 75173 818 0.623333333 1.16 0.896049036 Up 0.400936477 Tex38 testis expressed 38 - GO:0031224//intrinsic component of membrane - - gi|268370036|ref|NP_083472.1|/1.83477e-116/testis-expressed sequence 38 protein [Mus musculus] 66989 2400 12.46 10.53 -0.242798632 Down 0.40090827 Kctd20 potassium channel tetramerisation domain containing 20 K10482|1|3e-136|488|xtr:100379762|BTB/POZ domain-containing protein 10 - GO:0005515//protein binding GO:0051259//protein oligomerization "gi|148690652|gb|EDL22599.1|/0/potassium channel tetramerisation domain containing 20, isoform CRA_c, partial [Mus musculus]" 66706 1092 19.7 22.74666667 0.207459516 Up 0.400842454 Ndufaf3 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3" K09008|1|5e-105|383|mmu:66706|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0010257//NADH dehydrogenase complex assembly gi|12963603|ref|NP_075736.1|/4.49733e-104/NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 [Mus musculus] 80708 1873.63 97.47 85.92333333 -0.181908282 Down 0.400823649 Pacsin3 protein kinase C and casein kinase substrate in neurons 3 K20123|1|0.0|839|mmu:80708|protein kinase C and casein kinase substrate in neurons protein GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005515//protein binding" GO:0006509//membrane protein ectodomain proteolysis;GO:0006796//phosphate-containing compound metabolic process;GO:0006897//endocytosis;GO:0006509//membrane protein ectodomain proteolysis;GO:0006796//phosphate-containing compound metabolic process;GO:0006897//endocytosis;GO:0006509//membrane protein ectodomain proteolysis;GO:0006796//phosphate-containing compound metabolic process;GO:0006897//endocytosis;GO:0006509//membrane protein ectodomain proteolysis;GO:0006796//phosphate-containing compound metabolic process;GO:0006897//endocytosis "gi|148695609|gb|EDL27556.1|/0/protein kinase C and casein kinase substrate in neurons 3, isoform CRA_b, partial [Mus musculus]" 54634 2798.81 14.81333333 17.29666667 0.223597719 Up 0.400804844 Magix "MAGI family member, X-linked" K05631|1|2e-18|97.8|rno:500261|atrophin-1 interacting protein 3 (BAI1-associated protein 1) - - - gi|134053862|ref|NP_061302.2|/1.21736e-148/PDZ domain-containing protein MAGIX [Mus musculus] 66789 910 4.993333333 6.2 0.312264998 Up 0.40074843 Alg14 asparagine-linked glycosylation 14 "K07441|1|3e-111|403|mmu:66789|beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141]" GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0006487//protein N-linked glycosylation "gi|148680397|gb|EDL12344.1|/2.38053e-110/asparagine-linked glycosylation 14 homolog (yeast), isoform CRA_b [Mus musculus]" 12406 2241.28 88.58 100.01 0.17509136 Up 0.400720223 Serpinh1 "serine (or cysteine) peptidase inhibitor, clade H, member 1" "K09501|1|0.0|753|mmu:12406|serpin peptidase inhibitor, clade H, member 1" - - - gi|635016454|ref|XP_008018373.1|/0/PREDICTED: serpin H1 isoform X1 [Chlorocebus sabaeus] 106407 1544 0.6 0.19 -1.658963082 Down 0.400682613 Slc51a "solute carrier family 51, alpha subunit" K14360|1|3e-168|593|mmu:106407|organic solute transporter subunit alpha GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex GO:0042802//identical protein binding;GO:0046983//protein dimerization activity GO:0015718//monocarboxylic acid transport gi|22122353|ref|NP_666044.1|/2.7684e-167/organic solute transporter subunit alpha [Mus musculus] 23962 3136 7.22 8.71 0.270673882 Up 0.400645004 Oasl2 2'-5' oligoadenylate synthetase-like 2 K14608|1|0.0|969|mmu:23962|2'-5'-oligoadenylate synthase-like protein - GO:0043169//cation binding;GO:0032550;GO:0003723//RNA binding;GO:0070566//adenylyltransferase activity GO:0006952//defense response;GO:0051707//response to other organism;GO:0002252;GO:0006163//purine nucleotide metabolic process gi|134053898|ref|NP_035984.2|/0/2'-5'-oligoadenylate synthase-like protein 2 [Mus musculus] 27055 3011 39.33 44.88 0.19044249 Up 0.400616796 Fkbp9 FK506 binding protein 9 K09575|1|0.0|1133|mmu:27055|FK506-binding protein 9/10 [EC:5.2.1.8] - - - gi|172072617|ref|NP_036186.2|/0/peptidyl-prolyl cis-trans isomerase FKBP9 precursor [Mus musculus] 68915 4441 10.97 9.23 -0.249160973 Down 0.400588589 Vars2 "valyl-tRNA synthetase 2, mitochondrial" K01873|1|0.0|2132|mmu:68915|valyl-tRNA synthetase [EC:6.1.1.9] - - - - 216551 3635 10.42333333 12.34666667 0.244304879 Up 0.400541577 Lgalsl "lectin, galactoside binding-like" K06832|1|7e-24|115|bfo:BRAFLDRAFT_126856|galectin-8;K10093|3|5e-20|103|crg:105322757|galectin-9 GO:0044464 GO:0005488//binding - "gi|148675893|gb|EDL07840.1|/1.04308e-94/RIKEN cDNA 1110067D22, isoform CRA_a, partial [Mus musculus]" 544963 5771 0.953333333 0.466666667 -1.03058832 Down 0.400522773 Iqgap2 IQ motif containing GTPase activating protein 2 K05767|1|0.0|2966|mmu:544963|Ras GTPase-activating-like protein IQGAP2/3 GO:0015630//microtubule cytoskeleton GO:0008047//enzyme activator activity;GO:0008092//cytoskeletal protein binding;GO:0004857//enzyme inhibitor activity GO:0007264//small GTPase mediated signal transduction "gi|148668579|gb|EDL00898.1|/0/mCG114897, isoform CRA_a, partial [Mus musculus]" 16628 823 0.606666667 0.193333333 -1.649813645 Down 0.400419346 Klra10 "killer cell lectin-like receptor subfamily A, member 10" K17517|1|2e-16|88.2|ocu:100342539|C-type lectin domain family 12 member B;K10069|4|3e-14|81.3|myb:106725970|C-type lectin domain family 1 member A GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0051707//response to other organism;GO:0022610 "gi|9506839|ref|NP_032485.2|/5.48708e-153/killer cell lectin-like receptor subfamily A, member 10 [Mus musculus]" 50709 782 1.673333333 2.406666667 0.524311473 Up 0.400372334 Hist1h1e "histone cluster 1, H1e" K11275|1|1e-31|138|ngi:103733090|histone H1/5 GO:0043229//intracellular organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization gi|13430890|ref|NP_056602.1|/1.07256e-30/histone H1.4 [Mus musculus] 231532 2802.03 12.56666667 14.72 0.228175649 Up 0.400259506 Arhgap24 Rho GTPase activating protein 24 K07526|1|1e-27|127|tru:101075439|SLIT-ROBO Rho GTPase activating protein;K18470|4|7e-26|122|lgi:LOTGIDRAFT_168254|Rho GTPase-activating protein 1 GO:0005924//cell-substrate adherens junction;GO:0043232;GO:0005924//cell-substrate adherens junction;GO:0043232;GO:0005924//cell-substrate adherens junction;GO:0043232 GO:0008289//lipid binding;GO:0008289//lipid binding;GO:0008289//lipid binding "GO:0044319//wound healing, spreading of cells;GO:0016601//Rac protein signal transduction;GO:0048869//cellular developmental process;GO:0031345//negative regulation of cell projection organization;GO:0044319//wound healing, spreading of cells;GO:0016601//Rac protein signal transduction;GO:0048869//cellular developmental process;GO:0031345//negative regulation of cell projection organization;GO:0044319//wound healing, spreading of cells;GO:0016601//Rac protein signal transduction;GO:0048869//cellular developmental process;GO:0031345//negative regulation of cell projection organization" gi|170671704|ref|NP_083546.2|/0/rho GTPase-activating protein 24 isoform 1 [Mus musculus] 22379 4343.39 14.33666667 12.18666667 -0.234406061 Down 0.400259506 Fmnl3 formin-like 3 K04512|1|8e-39|166|dre:557451|dishevelled associated activator of morphogenesis - - - - 76781 2150 0.983333333 1.596666667 0.699310701 Up 0.400250103 Mettl4 methyltransferase like 4 K05925|1|7e-08|62.0|phu:Phum_PHUM423190|mRNA (2'-O-methyladenosine-N6-)-methyltransferase [EC:2.1.1.62] - GO:0016741 GO:0006725//cellular aromatic compound metabolic process gi|74315949|ref|NP_795891.2|/0/methyltransferase-like protein 4 [Mus musculus] 67872 1484 25.92 29.75 0.19882395 Up 0.400146677 Nsmce4a "NSE4 homolog A, SMC5-SMC6 complex component" - GO:0000793//condensed chromosome - GO:0006974//cellular response to DNA damage stimulus gi|242246981|ref|NP_001156327.1|/1.48774e-178/non-structural maintenance of chromosomes element 4 homolog A [Mus musculus] 97402 2020 1.076666667 1.706666667 0.664609645 Up 0.40011847 C86187 expressed sequence C86187 "K03873|1|1e-29|134|cge:100772696|transcription elongation factor B, polypeptide 2" - - - - 99311 3213 4.33 5.443333333 0.33012336 Up 0.400090263 Commd7 COMM domain containing 7 - - GO:0008134//transcription factor binding;GO:0008134//transcription factor binding GO:0019221//cytokine-mediated signaling pathway;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0019221//cytokine-mediated signaling pathway;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity "gi|148674081|gb|EDL06028.1|/3.76706e-112/COMM domain containing 7, isoform CRA_b, partial [Mus musculus]" 67606 2069 5.373333333 6.623333333 0.301740129 Up 0.400015044 Fibin fin bud initiation factor homolog (zebrafish) - GO:0043231//intracellular membrane-bounded organelle - - gi|13385776|ref|NP_080547.1|/5.18463e-122/fin bud initiation factor homolog precursor [Mus musculus] 68861 3950 6.27 5.066666667 -0.307428525 Down 0.399911618 1190002N15Rik RIKEN cDNA 1190002N15 gene - GO:0005798//Golgi-associated vesicle;GO:0030120//vesicle coat - GO:0006903//vesicle targeting gi|74145693|dbj|BAE24182.1|/0/unnamed protein product [Mus musculus] 19697 2709 24.93333333 28.73333333 0.204649599 Up 0.399902215 Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) K04735|1|0.0|1040|mmu:19697|transcription factor p65 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0019904//protein domain specific binding;GO:0000975//regulatory region DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0043168//anion binding;GO:0044389//ubiquitin-like protein ligase binding" GO:0042090;GO:0006954//inflammatory response;GO:0070555//response to interleukin-1;GO:0006915//apoptotic process;GO:0014037//Schwann cell differentiation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002062//chondrocyte differentiation;GO:0009653//anatomical structure morphogenesis;GO:0009895;GO:0014072//response to isoquinoline alkaloid;GO:0009411//response to UV;GO:0008544//epidermis development;GO:0009605//response to external stimulus;GO:0000302//response to reactive oxygen species;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0006081//cellular aldehyde metabolic process;GO:0046683//response to organophosphorus;GO:0001101//response to acid chemical;GO:0048545//response to steroid hormone;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0044767//single-organism developmental process;GO:0034612//response to tumor necrosis factor;GO:0008286//insulin receptor signaling pathway;GO:0032496//response to lipopolysaccharide gi|6677709|ref|NP_033071.1|/0/transcription factor p65 [Mus musculus] 435626 2336 1.133333333 1.77 0.643177115 Up 0.399826996 Rufy4 RUN and FYVE domain containing 4 - - GO:0043169//cation binding;GO:0043169//cation binding - gi|282165731|ref|NP_001164112.1|/0/RUN and FYVE domain-containing protein 4 isoform 1 [Mus musculus] 13211 4623 10.75666667 9.04 -0.250836399 Down 0.399779984 Dhx9 DEAH (Asp-Glu-Ala-His) box polypeptide 9 K13184|1|0.0|2085|mmu:13211|ATP-dependent RNA helicase A [EC:3.6.4.13] - - - "gi|148707490|gb|EDL39437.1|/0/DEAH (Asp-Glu-Ala-His) box polypeptide 9, isoform CRA_b, partial [Mus musculus]" 360013 6533.76 42.59333333 37.21666667 -0.194678794 Down 0.399695363 Myo18a myosin XVIIIA K10362|1|0.0|3106|mmu:360013|myosin XVIII GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization gi|600971682|ref|NP_001278142.1|/0/unconventional myosin-XVIIIa isoform 1 [Mus musculus] 226122 1527 12.57 14.70333333 0.22615861 Up 0.399620144 Ubtd1 ubiquitin domain containing 1 - - - - gi|21703984|ref|NP_663475.1|/1.92561e-96/ubiquitin domain-containing protein 1 [Mus musculus] 14747 2845 14.20333333 12.07333333 -0.234405505 Down 0.399620144 Cmklr1 chemokine-like receptor 1 K04245|1|0.0|688|mmu:14747|chemokine-like receptor 1 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0001818//negative regulation of cytokine production;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0019722//calcium-mediated signaling gi|33469077|ref|NP_032179.1|/0/chemokine-like receptor 1 [Mus musculus] 14700 1120 6.616666667 8.01 0.275697641 Up 0.399507315 Gng10 "guanine nucleotide binding protein (G protein), gamma 10" K04545|1|3e-26|121|rno:114119|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 GO:0031234//extrinsic component of cytoplasmic side of plasma membrane GO:0017111//nucleoside-triphosphatase activity;GO:0060089 GO:0009154//purine ribonucleotide catabolic process;GO:0007267//cell-cell signaling;GO:0033762//response to glucagon;GO:0007166//cell surface receptor signaling pathway;GO:0015980//energy derivation by oxidation of organic compounds "gi|148670268|gb|EDL02215.1|/3.09747e-47/guanine nucleotide binding protein (G protein), gamma 10, partial [Mus musculus]" 26429 2059 3.75 4.78 0.350120023 Up 0.399469706 Orc5 "origin recognition complex, subunit 5" K02607|1|0.0|882|mmu:26429|origin recognition complex subunit 5 GO:0000808//origin recognition complex;GO:0031981//nuclear lumen GO:0032550;GO:0043565//sequence-specific DNA binding GO:0006259//DNA metabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0051320 gi|6754948|ref|NP_036089.1|/0/origin recognition complex subunit 5 [Mus musculus] 236900 2000 0.92 1.516666667 0.721198278 Up 0.399441498 Pdk3 "pyruvate dehydrogenase kinase, isoenzyme 3" K00898|1|0.0|843|mmu:236900|pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2] GO:0044429 GO:0032550;GO:0004672//protein kinase activity GO:0006086//acetyl-CoA biosynthetic process from pyruvate;GO:0031323//regulation of cellular metabolic process;GO:0070542//response to fatty acid;GO:0006468//protein phosphorylation;GO:0006006//glucose metabolic process;GO:0030522//intracellular receptor signaling pathway;GO:0001678//cellular glucose homeostasis "gi|148697796|gb|EDL29743.1|/0/pyruvate dehydrogenase kinase, isoenzyme 3, isoform CRA_a, partial [Mus musculus]" 56693 1714 14.58333333 17.00333333 0.221497084 Up 0.399441498 Crtap cartilage associated protein K19606|1|0.0|721|mmu:56693|cartilage-associated protein GO:0044432;GO:0031012//extracellular matrix - GO:0043062//extracellular structure organization;GO:0019511//peptidyl-proline hydroxylation;GO:0048232//male gamete generation gi|880907637|ref|XP_005075156.2|/0/PREDICTED: cartilage-associated protein [Mesocricetus auratus] 78232 1286.95 25.19666667 28.95666667 0.200662648 Up 0.399403889 Trappc6b trafficking protein particle complex 6B K20304|1|8e-85|316|mmu:78232|trafficking protein particle complex subunit 6 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0006810//transport;GO:0006810//transport;GO:0006810//transport "gi|148704737|gb|EDL36684.1|/4.53217e-69/trafficking protein particle complex 6B, partial [Mus musculus]" 214931 3499 2.843333333 3.74 0.395455029 Up 0.399394486 Fbxl16 F-box and leucine-rich repeat protein 16 K10282|1|0.0|834|cge:100772347|F-box and leucine-rich repeat protein 16 - - - gi|625196105|ref|XP_003501609.2|/0/PREDICTED: F-box/LRR-repeat protein 16 isoform X3 [Cricetulus griseus] 104248 7483 9.596666667 8.033333333 -0.256534642 Down 0.399356877 Cabin1 calcineurin binding protein 1 K17613|1|0.0|3893|mmu:104248|calcineurin-binding protein cabin-1 GO:0016234//inclusion body;GO:0031981//nuclear lumen GO:0019903//protein phosphatase binding;GO:0019212//phosphatase inhibitor activity GO:0006325//chromatin organization;GO:0007165//signal transduction;GO:0008219//cell death;GO:0044092//negative regulation of molecular function gi|70995287|ref|NP_766137.2|/0/calcineurin-binding protein cabin-1 [Mus musculus] 228003 2538 37.98666667 43.23666667 0.186762182 Up 0.39913122 Klhl41 kelch-like 41 K10473|1|0.0|1185|mmu:228003|kelch repeat and BTB domain-containing protein 5/10 - - - - 320208 908 0.01 0.27 4.754887502 Up 0.39913122 Tmem91 transmembrane protein 91 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0050896//response to stimulus;GO:0050896//response to stimulus;GO:0050896//response to stimulus "gi|148692297|gb|EDL24244.1|/1.64984e-87/RIKEN cDNA A830041P22, isoform CRA_c, partial [Mus musculus]" 102465902 119 0.01 0.27 4.754887502 Up 0.39913122 Mir8115 microRNA 8115 - - - - - 14784 2646.05 37.14333333 42.39666667 0.190847549 Up 0.39913122 Grb2 growth factor receptor bound protein 2 K04364|1|2e-127|459|mmu:14784|growth factor receptor-binding protein 2 - - - - 69549 571 4.02 5.083333333 0.338579335 Up 0.399112415 2310009B15Rik RIKEN cDNA 2310009B15 gene K09373|1|8e-15|82.0|lcm:102364557|LIM homeobox protein 2/9;K02874|2|5e-11|69.3|bmy:Bm1_29670|large subunit ribosomal protein L14 - - - gi|124487011|ref|NP_001074695.1|/2.59988e-75/uncharacterized protein C1orf53 homolog [Mus musculus] 68646 3665.36 14.87666667 17.28333333 0.216330182 Up 0.399084208 Nadk2 "NAD kinase 2, mitochondrial" K00858|1|0.0|731|mmu:68646|NAD+ kinase [EC:2.7.1.23] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0042802//identical protein binding;GO:0016301//kinase activity;GO:0032550;GO:0042802//identical protein binding;GO:0016301//kinase activity;GO:0032550;GO:0042802//identical protein binding;GO:0016301//kinase activity GO:0006739//NADP metabolic process;GO:0006739//NADP metabolic process;GO:0006739//NADP metabolic process "gi|146134519|ref|NP_001035485.2|/0/NAD kinase 2, mitochondrial isoform 2 [Mus musculus]" 11630 7416 1.723333333 1.096666667 -0.652076697 Down 0.399046598 Aim1 absent in melanoma 1 K04257|1|1e-77|295|pon:100436530|olfactory receptor;K16810|2|3e-15|88.2|bacu:103015945|TBCC domain-containing protein 1 - - - gi|568964803|ref|XP_006512562.1|/0/PREDICTED: absent in melanoma 1 protein isoform X2 [Mus musculus] 108960 3202.45 5.936666667 7.233333333 0.285007526 Up 0.399046598 Irak2 interleukin-1 receptor-associated kinase 2 K04731|1|0.0|1259|mmu:108960|interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0016301//kinase activity;GO:0032550;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0016301//kinase activity;GO:0032550;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0032147//activation of protein kinase activity;GO:0019221//cytokine-mediated signaling pathway;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0009966//regulation of signal transduction;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0032147//activation of protein kinase activity;GO:0019221//cytokine-mediated signaling pathway;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0009966//regulation of signal transduction "gi|148667078|gb|EDK99494.1|/0/mCG132967, isoform CRA_b, partial [Mus musculus]" 211499 2923.32 4.35 5.453333333 0.326122941 Up 0.398980782 Tmem87a transmembrane protein 87A - - - - gi|160333208|ref|NP_001103967.1|/0/transmembrane protein 87A isoform 3 [Mus musculus] 78802 2862 2.686666667 1.92 -0.484711027 Down 0.398914965 Ttc30a1 tetratricopeptide repeat domain 30A1 K19683|1|0.0|1274|mmu:78802|tetratricopeptide repeat protein 30 - - - - 66155 964 37.12666667 42.31666667 0.188770197 Up 0.398745722 Ufc1 ubiquitin-fold modifier conjugating enzyme 1 K12165|1|4e-99|363|ngi:103745960|ufm1-conjugating enzyme 1 - GO:0005488//binding;GO:0019787//ubiquitin-like protein transferase activity GO:0032446//protein modification by small protein conjugation gi|674077614|ref|XP_008846233.1|/3.00842e-98/PREDICTED: ubiquitin-fold modifier-conjugating enzyme 1 isoform X1 [Nannospalax galili] 219024 1614.45 12.01333333 14.10333333 0.231399675 Up 0.398313212 Tmem55b transmembrane protein 55b "K13084|1|4e-56|152|phi:102101128|phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78]" GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0005770//late endosome;GO:0016020//membrane;GO:0005764//lysosome;GO:0005768//endosome;GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity - "gi|887236619|ref|NP_001297435.1|/2.25247e-121/type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform 3 [Mus musculus]" 66153 900 2.31 1.596666667 -0.532829696 Down 0.398275603 Fbxo36 F-box protein 36 K10312|1|1e-95|352|mmu:66153|F-box protein 36 - - - gi|13384764|ref|NP_079662.1|/8.01686e-95/F-box only protein 36 [Mus musculus] 106861 1903 1.406666667 2.083333333 0.566613191 Up 0.398247396 Abhd3 abhydrolase domain containing 3 K13696|1|0.0|810|mmu:106861|abhydrolase domain-containing protein 1/3 - - - - 101122 1269 5.286666667 6.516666667 0.301775836 Up 0.398190981 Rpusd3 RNA pseudouridylate synthase domain containing 3 K01855|1|5e-25|117|mgp:100543853|tRNA pseudouridine38/39 synthase [EC:5.4.99.45] - GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity GO:0016070//RNA metabolic process gi|226494518|ref|NP_001028376.1|/0/RNA pseudouridylate synthase domain-containing protein 3 [Mus musculus] 442801 4213 28.57 24.93 -0.196618153 Down 0.398190981 Arhgef15 Rho guanine nucleotide exchange factor (GEF) 15 K07525|1|4e-74|283|cmk:103190558|neuronal guanine nucleotide exchange factor GO:0043005//neuron projection GO:0008047//enzyme activator activity;GO:0005488//binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0019222//regulation of metabolic process;GO:0051093//negative regulation of developmental process;GO:0009653//anatomical structure morphogenesis;GO:0007266//Rho protein signal transduction gi|60279700|ref|NP_808234.2|/0/rho guanine nucleotide exchange factor 15 [Mus musculus] 80752 3001 5.283333333 6.516666667 0.302685767 Up 0.398190981 Fam20c "family with sequence similarity 20, member C" K19347|1|5e-147|524|ccw:104696523|SUN domain-containing protein 1/2;K00327|2|8e-66|254|tsp:Tsp_02446|NADPH-ferrihemoprotein reductase [EC:1.6.2.4] GO:0044421 GO:0004672//protein kinase activity;GO:0046872//metal ion binding GO:0042475//odontogenesis of dentin-containing tooth;GO:0006464//cellular protein modification process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0030282//bone mineralization;GO:0034505//tooth mineralization;GO:0006796//phosphate-containing compound metabolic process;GO:0001649//osteoblast differentiation;GO:0036035//osteoclast development gi|167234439|ref|NP_085042.2|/0/extracellular serine/threonine protein kinase FAM20C precursor [Mus musculus] 14613 3180 4.77 3.746666667 -0.348381637 Down 0.398134567 Gja5 "gap junction protein, alpha 5" "K07614|1|0.0|705|mmu:14613|gap junction protein, alpha 5" GO:0005921//gap junction;GO:0044291//cell-cell contact zone;GO:0044464;GO:0016021//integral component of membrane;GO:0005921//gap junction;GO:0044291//cell-cell contact zone;GO:0044464;GO:0016021//integral component of membrane GO:0005515//protein binding;GO:0086075//gap junction channel activity involved in cardiac conduction electrical coupling;GO:0005515//protein binding;GO:0086075//gap junction channel activity involved in cardiac conduction electrical coupling GO:0002027//regulation of heart rate;GO:0009888//tissue development;GO:0007043//cell-cell junction assembly;GO:0030001//metal ion transport;GO:0006461//protein complex assembly;GO:0001944//vasculature development;GO:0035108//limb morphogenesis;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0019229//regulation of vasoconstriction;GO:0003209//cardiac atrium morphogenesis;GO:0060306//regulation of membrane repolarization;GO:0042311//vasodilation;GO:0003254//regulation of membrane depolarization;GO:0010643//cell communication by chemical coupling;GO:0003283//atrial septum development;GO:0044060//regulation of endocrine process;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0009790//embryo development;GO:0003281//ventricular septum development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0003093//regulation of glomerular filtration;GO:0003184//pulmonary valve morphogenesis;GO:0002027//regulation of heart rate;GO:0009888//tissue development;GO:0007043//cell-cell junction assembly;GO:0030001//metal ion transport;GO:0006461//protein complex assembly;GO:0001944//vasculature development;GO:0035108//limb morphogenesis;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0019229//regulation of vasoconstriction;GO:0003209//cardiac atrium morphogenesis;GO:0060306//regulation of membrane repolarization;GO:0042311//vasodilation;GO:0003254//regulation of membrane depolarization;GO:0010643//cell communication by chemical coupling;GO:0003283//atrial septum development;GO:0044060//regulation of endocrine process;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0009790//embryo development;GO:0003281//ventricular septum development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0003093//regulation of glomerular filtration;GO:0003184//pulmonary valve morphogenesis gi|6680005|ref|NP_032147.1|/0/gap junction alpha-5 protein [Mus musculus] 194309 1306 0.336666667 0.79 1.230531766 Up 0.398125165 Vps37d vacuolar protein sorting 37D K12185|1|1e-90|336|rno:687208|ESCRT-I complex subunit VPS37 GO:0005768//endosome;GO:0031090//organelle membrane - GO:0051234//establishment of localization;GO:0044765//single-organism transport;GO:0044763 gi|189491873|ref|NP_001121665.1|/8.09651e-90/vacuolar protein sorting-associated protein 37D [Rattus norvegicus] 71086 1511 1.286666667 1.943333333 0.594895036 Up 0.398115762 4933412E12Rik RIKEN cDNA 4933412E12 gene - - - - - 66164 3036 4.94 6.12 0.309020611 Up 0.397993531 Nip7 "NIP7, nucleolar pre-rRNA processing protein" K07565|1|5e-95|352|mmu:66164|60S ribosome subunit biogenesis protein NIP7 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0042254//ribosome biogenesis;GO:0042254//ribosome biogenesis;GO:0042254//ribosome biogenesis gi|257153334|ref|NP_001157944.1|/2.36074e-70/60S ribosome subunit biogenesis protein NIP7 homolog isoform 2 [Mus musculus] 228140 5781 16.38333333 14.02666667 -0.224056712 Down 0.397974726 Tnks1bp1 tankyrase 1 binding protein 1 - - - - gi|124486923|ref|NP_001074729.1|/0/182 kDa tankyrase-1-binding protein [Mus musculus] 11464 1461 10999.34333 12375.32667 0.170049211 Up 0.397965324 Actc1 "actin, alpha, cardiac muscle 1" "K12314|1|0.0|766|ccw:104684380|actin, alpha cardiac muscle" - - - - 235599 2552 2.606666667 1.853333333 -0.492083725 Down 0.397918312 6430571L13Rik RIKEN cDNA 6430571L13 gene - GO:0031224//intrinsic component of membrane - - gi|28202049|ref|NP_780695.1|/2.04254e-62/uncharacterized protein C3orf18 homolog [Mus musculus] 109344 936 1.07 1.69 0.65941245 Up 0.397777276 E130215H24Rik RIKEN cDNA E130215H24 gene K01895|1|4e-10|67.8|rno:296259|acetyl-CoA synthetase [EC:6.2.1.1] - - - - 100040525 4045 0.453333333 0.93 1.036658471 Up 0.397626838 Tmem181c-ps "transmembrane protein 181C, pseudogene" - - GO:0005488//binding - gi|75677514|ref|NP_001028350.1|/1.81548e-87/transmembrane protein 181 [Mus musculus] 76380 1863.82 0.46 0.943333333 1.036133786 Up 0.397626838 Cep112 centrosomal protein 112 K16767|1|1e-79|299|mmu:76380|centrosomal protein CEP112 GO:0005815//microtubule organizing center;GO:0016020//membrane;GO:0045202//synapse;GO:0005815//microtubule organizing center;GO:0016020//membrane;GO:0045202//synapse;GO:0005815//microtubule organizing center;GO:0016020//membrane;GO:0045202//synapse - GO:0035418//protein localization to synapse;GO:0035418//protein localization to synapse;GO:0035418//protein localization to synapse gi|568976255|ref|XP_006534487.1|/0/PREDICTED: centrosomal protein of 112 kDa isoform X2 [Mus musculus] 66067 1318 4.013333333 3.083333333 -0.380310121 Down 0.397495205 Gtpbp8 GTP-binding protein 8 (putative) - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0032550 GO:0090529;GO:0090529 gi|21313623|ref|NP_079608.1|/1.88558e-158/GTP-binding protein 8 isoform 1 [Mus musculus] 72306 3111 7.873333333 9.403333333 0.256197701 Up 0.397391779 Zfp777 zinc finger protein 777 K09228|1|0.0|1533|mmu:72306|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|124487043|ref|NP_001074851.1|/0/zinc finger protein 777 [Mus musculus] 66994 1701 5.21 6.43 0.303535365 Up 0.397372974 Cep19 centrosomal protein 19 K16801|1|1e-90|336|rno:192229|centrosomal protein CEP19 GO:0005819//spindle;GO:0005813//centrosome - - gi|830260261|ref|NP_620220.2|/9.04865e-90/centrosomal protein of 19 kDa [Rattus norvegicus] 24000 5562 8.47 7.026666667 -0.269521508 Down 0.397372974 Ptpn21 "protein tyrosine phosphatase, non-receptor type 21" K18025|1|0.0|2277|mmu:24000|tyrosine-protein phosphatase non-receptor type 14/21 [EC:3.1.3.48] GO:0043232;GO:0043232 GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity GO:0006470//protein dephosphorylation;GO:0006996//organelle organization;GO:0006470//protein dephosphorylation;GO:0006996//organelle organization gi|226246561|ref|NP_036007.2|/0/tyrosine-protein phosphatase non-receptor type 21 [Mus musculus] 22260 2017.88 33.98666667 38.90333333 0.194924902 Up 0.397250743 Nr1h2 "nuclear receptor subfamily 1, group H, member 2" K08535|1|0.0|667|mmu:22260|liver X receptor beta GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0042974//retinoic acid receptor binding;GO:0001010//transcription factor activity, sequence-specific DNA binding transcription factor recruiting;GO:0038023//signaling receptor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0042974//retinoic acid receptor binding;GO:0001010//transcription factor activity, sequence-specific DNA binding transcription factor recruiting;GO:0038023//signaling receptor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0042974//retinoic acid receptor binding;GO:0001010//transcription factor activity, sequence-specific DNA binding transcription factor recruiting;GO:0038023//signaling receptor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0042974//retinoic acid receptor binding;GO:0001010//transcription factor activity, sequence-specific DNA binding transcription factor recruiting;GO:0038023//signaling receptor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding" GO:0006633//fatty acid biosynthetic process;GO:0010883//regulation of lipid storage;GO:0031325//positive regulation of cellular metabolic process;GO:0055092//sterol homeostasis;GO:0006508//proteolysis;GO:0050714//positive regulation of protein secretion;GO:0051004;GO:0010878//cholesterol storage;GO:0030522//intracellular receptor signaling pathway;GO:0006907//pinocytosis;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0010866//regulation of triglyceride biosynthetic process;GO:0010874//regulation of cholesterol efflux;GO:0051130//positive regulation of cellular component organization;GO:0006633//fatty acid biosynthetic process;GO:0010883//regulation of lipid storage;GO:0031325//positive regulation of cellular metabolic process;GO:0055092//sterol homeostasis;GO:0006508//proteolysis;GO:0050714//positive regulation of protein secretion;GO:0051004;GO:0010878//cholesterol storage;GO:0030522//intracellular receptor signaling pathway;GO:0006907//pinocytosis;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0010866//regulation of triglyceride biosynthetic process;GO:0010874//regulation of cholesterol efflux;GO:0051130//positive regulation of cellular component organization;GO:0006633//fatty acid biosynthetic process;GO:0010883//regulation of lipid storage;GO:0031325//positive regulation of cellular metabolic process;GO:0055092//sterol homeostasis;GO:0006508//proteolysis;GO:0050714//positive regulation of protein secretion;GO:0051004;GO:0010878//cholesterol storage;GO:0030522//intracellular receptor signaling pathway;GO:0006907//pinocytosis;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0010866//regulation of triglyceride biosynthetic process;GO:0010874//regulation of cholesterol efflux;GO:0051130//positive regulation of cellular component organization;GO:0006633//fatty acid biosynthetic process;GO:0010883//regulation of lipid storage;GO:0031325//positive regulation of cellular metabolic process;GO:0055092//sterol homeostasis;GO:0006508//proteolysis;GO:0050714//positive regulation of protein secretion;GO:0051004;GO:0010878//cholesterol storage;GO:0030522//intracellular receptor signaling pathway;GO:0006907//pinocytosis;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0010866//regulation of triglyceride biosynthetic process;GO:0010874//regulation of cholesterol efflux;GO:0051130//positive regulation of cellular component organization "gi|148690788|gb|EDL22735.1|/0/nuclear receptor subfamily 1, group H, member 2, isoform CRA_a, partial [Mus musculus]" 52065 6408 12.16 10.32666667 -0.235768585 Down 0.397015683 Mfhas1 malignant fibrous histiocytoma amplified sequence 1 K08843|1|9e-28|129|cjo:107318963|leucine-rich repeat kinase 1 [EC:2.7.11.1] - - - gi|124486881|ref|NP_001074748.1|/0/malignant fibrous histiocytoma-amplified sequence 1 homolog [Mus musculus] 394435 2293 0.06 0.4 2.736965594 Up 0.396987476 Ugt1a6b "UDP glucuronosyltransferase 1 family, polypeptide A6B" K00699|1|0.0|1086|mmu:394435|glucuronosyltransferase [EC:2.4.1.17] GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0005501//retinoid binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0008194//UDP-glycosyltransferase activity GO:0006063;GO:0051384//response to glucocorticoid;GO:0002237//response to molecule of bacterial origin;GO:0006725//cellular aromatic compound metabolic process "gi|284413688|ref|NP_958812.3|/0/UDP glucuronosyltransferase 1 family, polypeptide A6B precursor [Mus musculus]" 67512 1574 35.04666667 39.92666667 0.188075397 Up 0.396978074 Agpat2 "1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)" K13509|1|2e-142|508|mmu:67512|lysophosphatidate acyltransferase [EC:2.3.1.51] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0016411//acylglycerol O-acyltransferase activity GO:0046473//phosphatidic acid metabolic process gi|23956162|ref|NP_080488.1|/2.05226e-141/1-acyl-sn-glycerol-3-phosphate acyltransferase beta precursor [Mus musculus] 231637 3174 1.913333333 1.26 -0.602664502 Down 0.396968671 Ssh1 slingshot homolog 1 (Drosophila) K05766|1|0.0|1880|mmu:231637|protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48] GO:0043232;GO:0016020//membrane GO:0004721//phosphoprotein phosphatase activity GO:0031323//regulation of cellular metabolic process;GO:0007010//cytoskeleton organization;GO:0051128//regulation of cellular component organization;GO:0006796//phosphate-containing compound metabolic process;GO:0033198//response to ATP gi|47271413|ref|NP_932777.2|/0/protein phosphatase Slingshot homolog 1 [Mus musculus] 12306 1374 73.08333333 64.32666667 -0.184125505 Down 0.396968671 Anxa2 annexin A2 K17092|1|0.0|671|mmu:12306|annexin A2 GO:0032991//macromolecular complex;GO:0032432//actin filament bundle;GO:0043218//compact myelin;GO:0048770;GO:0005578//proteinaceous extracellular matrix;GO:0005768//endosome;GO:0019898//extrinsic component of membrane;GO:0005886//plasma membrane GO:0005543//phospholipid binding;GO:0055102//lipase inhibitor activity;GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0017016//Ras GTPase binding;GO:0043168//anion binding GO:0030198//extracellular matrix organization;GO:0006906//vesicle fusion;GO:0042730//fibrinolysis;GO:0044092//negative regulation of molecular function;GO:0001101//response to acid chemical;GO:0044093;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0046903//secretion gi|965943696|ref|XP_014952164.1|/0/PREDICTED: annexin A2 isoform X1 [Ovis aries] 12355 1322 2.656666667 3.523333333 0.407323747 Up 0.396912257 Nr1i3 "nuclear receptor subfamily 1, group I, member 3" K08541|1|0.0|670|mmu:12355|constitutive androstane receptor GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0044444//cytoplasmic part "GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding" "GO:0009755//hormone-mediated signaling pathway;GO:0006351//transcription, DNA-templated" gi|83921568|ref|NP_033933.2|/0/nuclear receptor subfamily 1 group I member 3 isoform 1 [Mus musculus] 70451 1744 2.683333333 3.556666667 0.406499488 Up 0.396912257 Dhrs13 dehydrogenase/reductase (SDR family) member 13 K11169|1|7e-176|619|mmu:70451|dehydrogenase/reductase SDR family member 13 [EC:1.1.-.-] - - - - 71982 2506.11 2.683333333 3.553333333 0.40514675 Up 0.396912257 Snx10 sorting nexin 10 K17924|1|5e-87|325|mmu:71982|sorting nexin-10/11 GO:0010008//endosome membrane;GO:0010008//endosome membrane;GO:0010008//endosome membrane GO:0035091//phosphatidylinositol binding;GO:0035091//phosphatidylinositol binding;GO:0035091//phosphatidylinositol binding GO:0045184//establishment of protein localization;GO:0006996//organelle organization;GO:0045184//establishment of protein localization;GO:0006996//organelle organization;GO:0045184//establishment of protein localization;GO:0006996//organelle organization gi|74139790|dbj|BAE31740.1|/4.55108e-86/unnamed protein product [Mus musculus] 68606 4933 10.57666667 8.92 -0.245769405 Down 0.39688405 Ppm1f protein phosphatase 1F (PP2C domain containing) K17502|1|0.0|848|mmu:68606|protein phosphatase 1F [EC:3.1.3.16] GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part GO:0004723//calcium-dependent protein serine/threonine phosphatase activity;GO:0043169//cation binding "GO:0032233//positive regulation of actin filament bundle assembly;GO:0006351//transcription, DNA-templated;GO:0010631//epithelial cell migration;GO:0040007//growth;GO:0006469//negative regulation of protein kinase activity;GO:0006915//apoptotic process;GO:0001954//positive regulation of cell-matrix adhesion;GO:0042493//response to drug;GO:0006935//chemotaxis;GO:0006470//protein dephosphorylation;GO:0035556//intracellular signal transduction" gi|28849881|ref|NP_789803.1|/0/protein phosphatase 1F [Mus musculus] 28146 2457 8.626666667 10.28666667 0.253900445 Up 0.39688405 Serp1 stress-associated endoplasmic reticulum protein 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0005874//microtubule;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0030529//intracellular ribonucleoprotein complex - GO:0006412//translation;GO:0035265//organ growth;GO:0050796//regulation of insulin secretion;GO:0030252//growth hormone secretion;GO:0019318//hexose metabolic process;GO:0045184//establishment of protein localization;GO:0009887//organ morphogenesis;GO:0006464//cellular protein modification process;GO:0030968//endoplasmic reticulum unfolded protein response gi|821005859|ref|XP_012366117.1|/2.25473e-32/PREDICTED: stress-associated endoplasmic reticulum protein 1 isoform X1 [Nomascus leucogenys] 244958 1948 0.64 0.223333333 -1.51887331 Down 0.396752416 Mrap2 melanocortin 2 receptor accessory protein 2 - GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0031779//melanocortin receptor binding;GO:0031779//melanocortin receptor binding GO:0034613//cellular protein localization;GO:0006171//cAMP biosynthetic process;GO:0034613//cellular protein localization;GO:0006171//cAMP biosynthetic process gi|568961493|ref|XP_006511236.1|/1.06261e-114/PREDICTED: melanocortin-2 receptor accessory protein 2 isoform X2 [Mus musculus] 66914 956.98 65.63333333 74.23 0.177573663 Up 0.396705404 Vps28 vacuolar protein sorting 28 K12184|1|3e-119|421|mmu:66914|ESCRT-I complex subunit VPS28 GO:0005770//late endosome;GO:0016020//membrane;GO:0005770//late endosome;GO:0016020//membrane - GO:0045184//establishment of protein localization;GO:0016567//protein ubiquitination;GO:0045184//establishment of protein localization;GO:0016567//protein ubiquitination gi|221222832|sp|B5DEN9.1|VPS28_RAT/1.85831e-121/RecName: Full=Vacuolar protein sorting-associated protein 28 homolog 269941 4176 2.503333333 3.34 0.415997696 Up 0.3966866 Chsy1 chondroitin sulfate synthase 1 K13499|1|0.0|1546|mmu:269941|chondroitin sulfate synthase [EC:2.4.1.175 2.4.1.226] GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane GO:0015020//glucuronosyltransferase activity;GO:0043169//cation binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0006024//glycosaminoglycan biosynthetic process;GO:0001503//ossification;GO:0044238//primary metabolic process;GO:0006790//sulfur compound metabolic process;GO:0009991//response to extracellular stimulus gi|124487199|ref|NP_001074632.1|/0/chondroitin sulfate synthase 1 precursor [Mus musculus] 328162 2192.9 2.063333333 2.843333333 0.462606332 Up 0.396620783 Trmt61a tRNA methyltransferase 61A K07442|1|1e-168|596|mmu:328162|tRNA (adenine57-N1/adenine58-N1)-methyltransferase [EC:2.1.1.219 2.1.1.220] GO:0043527//tRNA methyltransferase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043527//tRNA methyltransferase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043527//tRNA methyltransferase complex;GO:0043231//intracellular membrane-bounded organelle GO:0016426//tRNA (adenine) methyltransferase activity;GO:0016426//tRNA (adenine) methyltransferase activity;GO:0016426//tRNA (adenine) methyltransferase activity GO:0006399//tRNA metabolic process;GO:0001510//RNA methylation;GO:0006399//tRNA metabolic process;GO:0001510//RNA methylation;GO:0006399//tRNA metabolic process;GO:0001510//RNA methylation gi|152963551|ref|NP_796348.2|/9.95256e-168/tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A [Mus musculus] 19687 4731 6.4 5.19 -0.302337367 Down 0.396442138 Rfc1 replication factor C (activator 1) 1 K10754|1|0.0|1950|mmu:19687|replication factor C subunit 1 GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0005657//replication fork GO:0032550;GO:0005515//protein binding;GO:0016462//pyrophosphatase activity;GO:0043566//structure-specific DNA binding "GO:0006259//DNA metabolic process;GO:0006351//transcription, DNA-templated" "gi|148705785|gb|EDL37732.1|/0/replication factor C 1, isoform CRA_a, partial [Mus musculus]" 21922 1009 27.03333333 23.52666667 -0.200442484 Down 0.396404528 Clec3b "C-type lectin domain family 3, member b" K17520|1|4e-108|393|mmu:21922|C-type lectin domain family 3 member B GO:0044452//nucleolar part;GO:0031012//extracellular matrix;GO:0044421 GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0019904//protein domain specific binding GO:0071363//cellular response to growth factor stimulus;GO:0048731//system development;GO:0001503//ossification;GO:0010755//regulation of plasminogen activation gi|171184425|ref|NP_035736.2|/2.92702e-107/tetranectin precursor [Mus musculus] 209497 5271.07 9.003333333 7.493333333 -0.264851604 Down 0.3962917 Tmem164 transmembrane protein 164 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|54633300|ref|NP_808260.2|/3.02081e-162/transmembrane protein 164 isoform a [Mus musculus] 102866 3140.75 16.24 13.94 -0.220321071 Down 0.396235285 Pls3 plastin 3 (T-isoform) K17336|1|0.0|1238|mmu:102866|plastin-3 - - - - 76187 3139 19.99 17.22333333 -0.214914089 Down 0.396160066 Adhfe1 "alcohol dehydrogenase, iron containing, 1" K11173|1|0.0|811|mmu:76187|hydroxyacid-oxoacid transhydrogenase [EC:1.1.99.24] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0043169//cation binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0043169//cation binding" GO:0044710;GO:0006818//hydrogen transport;GO:0044710;GO:0006818//hydrogen transport "gi|30424876|ref|NP_780445.1|/0/hydroxyacid-oxoacid transhydrogenase, mitochondrial [Mus musculus]" 231801 2920 11.95333333 13.98333333 0.226295322 Up 0.396160066 Agfg2 ArfGAP with FG repeats 2 K15044|1|3e-87|326|lcm:102345586|Arf-GAP domain and FG repeats-containing protein 1 - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0032012//regulation of ARF protein signal transduction;GO:0032012//regulation of ARF protein signal transduction;GO:0032012//regulation of ARF protein signal transduction gi|740087244|ref|NP_001290195.1|/0/arf-GAP domain and FG repeat-containing protein 2 isoform 3 [Mus musculus] 11744 2413 64.58333333 72.92666667 0.175284548 Up 0.396113054 Anxa11 annexin A11 K17095|1|0.0|643|mmu:11744|annexin A7/11 GO:0030141//secretory granule;GO:0015630//microtubule cytoskeleton;GO:0031981//nuclear lumen;GO:0005766;GO:0030139//endocytic vesicle;GO:0012505//endomembrane system;GO:0048770 GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0005515//protein binding GO:0010038//response to metal ion;GO:0000920//cell separation after cytokinesis;GO:0006897//endocytosis "gi|148669465|gb|EDL01412.1|/0/annexin A11, isoform CRA_b [Mus musculus]" 59308 1467.11 33.91666667 38.65 0.188474025 Up 0.396113054 Emcn endomucin K16664|1|1e-100|369|mmu:59308|endomucin GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|254588120|ref|NP_058581.2|/1.27345e-102/endomucin isoform 2 precursor [Mus musculus] 319151 470 0.103333333 0.47 2.185355042 Up 0.396103652 Hist1h3e "histone cluster 1, H3e" K11253|1|1e-64|246|aqu:100635211|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|831277892|ref|XP_012669845.1|/4.66143e-64/PREDICTED: uncharacterized protein LOC105888650 [Clupea harengus] 11782 1113 33.13666667 37.84666667 0.191737757 Up 0.395990823 Ap4s1 "adaptor-related protein complex AP-4, sigma 1" K12403|1|3e-75|284|mmu:11782|AP-4 complex subunit sigma-1 GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle GO:0022892//substrate-specific transporter activity GO:0015031//protein transport "gi|148704831|gb|EDL36778.1|/2.57536e-78/adaptor-related protein complex AP-4, sigma 1, isoform CRA_b, partial [Mus musculus]" 29875 7377 7.546666667 6.21 -0.281246284 Down 0.395972019 Iqgap1 IQ motif containing GTPase activating protein 1 K16848|1|0.0|3167|mmu:29875|Ras GTPase-activating-like protein IQGAP1 GO:0030054//cell junction;GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton;GO:0044459;GO:0042995//cell projection GO:0008047//enzyme activator activity;GO:0019900//kinase binding;GO:0019902//phosphatase binding;GO:0017048//Rho GTPase binding GO:0007264//small GTPase mediated signal transduction;GO:0016311//dephosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0051592//response to calcium ion gi|37359752|dbj|BAC97854.1|/0/mKIAA0051 protein [Mus musculus] 231868 2343 8.616666667 10.25666667 0.251360163 Up 0.395868592 E130309D02Rik RIKEN cDNA E130309D02 gene K04594|1|2e-11|73.6|ptg:102960959|latrophilin 3 - - - gi|170650679|ref|NP_766314.3|/0/uncharacterized protein C7orf26 homolog [Mus musculus] 72658 1126.01 4.133333333 5.203333333 0.332130417 Up 0.395793373 2700097O09Rik RIKEN cDNA 2700097O09 gene K11583|1|5e-10|67.8|mmu:100039830|serine/threonine-protein phosphatase 2A regulatory subunit B'' - - - gi|268607551|ref|NP_082590.2|/9.04241e-166/uncharacterized protein LOC72658 [Mus musculus] 71844 2410 5.226666667 4.16 -0.329307625 Down 0.395793373 Nupl1 nucleoporin like 1 K14307|1|2e-148|529|mmu:71844|nucleoporin p58/p45 GO:0005635//nuclear envelope GO:0005488//binding GO:0051169//nuclear transport gi|24497431|ref|NP_733479.1|/1.47156e-147/nucleoporin p58/p45 [Mus musculus] 56495 1280 60.98333333 69.11 0.180479469 Up 0.395736959 Asna1 "arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)" K01551|1|7e-179|629|pale:102878838|arsenite-transporting ATPase [EC:3.6.3.16] GO:0031981//nuclear lumen GO:0015103//inorganic anion transmembrane transporter activity;GO:0017111//nucleoside-triphosphatase activity;GO:0043169//cation binding;GO:0032550 GO:0009636//response to toxic substance;GO:0009154//purine ribonucleotide catabolic process;GO:0051234//establishment of localization gi|967496124|ref|XP_014978516.1|/5.97819e-178/PREDICTED: ATPase ASNA1 [Macaca mulatta] 66152 444 419.6833333 473.0066667 0.172559346 Up 0.395511302 Uqcr10 "ubiquinol-cytochrome c reductase, complex III subunit X" K00419|1|1e-30|133|mmu:66152|ubiquinol-cytochrome c reductase subunit 9 GO:0005746//mitochondrial respiratory chain - GO:0051234//establishment of localization;GO:0022904//respiratory electron transport chain gi|478511177|ref|XP_004429860.1|/4.35733e-30/PREDICTED: cytochrome b-c1 complex subunit 9 [Ceratotherium simum simum] 107589 7809 8.333333333 6.92 -0.268121651 Down 0.395379668 Mylk "myosin, light polypeptide kinase" K00907|1|0.0|3723|mmu:107589|myosin-light-chain kinase [EC:2.7.11.18] GO:0032432//actin filament bundle;GO:0032155;GO:0031252//cell leading edge GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0043169//cation binding GO:0035909//aorta morphogenesis;GO:0006816//calcium ion transport;GO:0006796//phosphate-containing compound metabolic process;GO:0006971//hypotonic response;GO:0030031//cell projection assembly;GO:0006464//cellular protein modification process;GO:0006939//smooth muscle contraction;GO:0048584;GO:0016477//cell migration "gi|126157499|ref|NP_647461.3|/0/myosin light chain kinase, smooth muscle [Mus musculus]" 216516 5069.36 3.28 2.45 -0.420914066 Down 0.395238633 Ccdc157 coiled-coil domain containing 157 - - - - gi|74221695|dbj|BAE21539.1|/0/unnamed protein product [Mus musculus] 113868 1758 32.54333333 37.13333333 0.190352797 Up 0.39522923 Acaa1a acetyl-Coenzyme A acyltransferase 1A K07513|1|0.0|798|mmu:113868|acetyl-CoA acyltransferase 1 [EC:2.3.1.16] GO:0042579//microbody GO:0005488//binding;GO:0003988//acetyl-CoA C-acyltransferase activity;GO:0003997//acyl-CoA oxidase activity GO:0009725//response to hormone;GO:0031667//response to nutrient levels;GO:0009062//fatty acid catabolic process;GO:0008202//steroid metabolic process "gi|18700004|ref|NP_570934.1|/0/3-ketoacyl-CoA thiolase A, peroxisomal precursor [Mus musculus]" 15162 2107 1.126666667 1.75 0.635294176 Up 0.395210425 Hck hemopoietic cell kinase K08893|1|0.0|1050|mmu:15162|hemopoietic cell kinase [EC:2.7.10.2] "GO:0000323//lytic vacuole;GO:0015629//actin cytoskeleton;GO:0009898//cytoplasmic side of plasma membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005924//cell-substrate adherens junction;GO:0000323//lytic vacuole;GO:0015629//actin cytoskeleton;GO:0009898//cytoplasmic side of plasma membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005924//cell-substrate adherens junction" GO:0004713//protein tyrosine kinase activity;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0032550 "GO:0006954//inflammatory response;GO:0050688//regulation of defense response to virus;GO:0006915//apoptotic process;GO:0043254//regulation of protein complex assembly;GO:0009888//tissue development;GO:0031532//actin cytoskeleton reorganization;GO:0019221//cytokine-mediated signaling pathway;GO:0042742//defense response to bacterium;GO:0022610;GO:0008283//cell proliferation;GO:0022604//regulation of cell morphogenesis;GO:0030041//actin filament polymerization;GO:0002218//activation of innate immune response;GO:0006468//protein phosphorylation;GO:0002679//respiratory burst involved in defense response;GO:0006909//phagocytosis;GO:0006355//regulation of transcription, DNA-templated;GO:0006954//inflammatory response;GO:0050688//regulation of defense response to virus;GO:0006915//apoptotic process;GO:0043254//regulation of protein complex assembly;GO:0009888//tissue development;GO:0031532//actin cytoskeleton reorganization;GO:0019221//cytokine-mediated signaling pathway;GO:0042742//defense response to bacterium;GO:0022610;GO:0008283//cell proliferation;GO:0022604//regulation of cell morphogenesis;GO:0030041//actin filament polymerization;GO:0002218//activation of innate immune response;GO:0006468//protein phosphorylation;GO:0002679//respiratory burst involved in defense response;GO:0006909//phagocytosis;GO:0006355//regulation of transcription, DNA-templated" gi|34734056|ref|NP_034537.2|/0/tyrosine-protein kinase HCK isoform p59Hck [Mus musculus] 107503 1831.07 59.08666667 66.94 0.180035938 Up 0.395182218 Atf5 activating transcription factor 5 K09044|1|3e-57|225|mmu:107503|activating transcription factor 5 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated;GO:0048699//generation of neurons;GO:0048468//cell development;GO:0021988//olfactory lobe development;GO:0048523//negative regulation of cellular process;GO:0006351//transcription, DNA-templated;GO:0048699//generation of neurons;GO:0048468//cell development;GO:0021988//olfactory lobe development;GO:0048523//negative regulation of cellular process" gi|13507624|ref|NP_109618.1|/2.34102e-56/cyclic AMP-dependent transcription factor ATF-5 [Mus musculus] 18452 2282.07 26.79666667 23.38333333 -0.196572947 Down 0.395116402 P4ha2 "procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide" K00472|1|0.0|1053|mmu:18452|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix "GO:0019842//vitamin binding;GO:0046914//transition metal ion binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0019842//vitamin binding;GO:0046914//transition metal ion binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0019471//4-hydroxyproline metabolic process;GO:0019471//4-hydroxyproline metabolic process "gi|148701600|gb|EDL33547.1|/0/procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide, isoform CRA_e, partial [Mus musculus]" 83797 3153 17.59666667 20.30666667 0.206651276 Up 0.395078792 Smarcd1 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1" K11650|1|0.0|934|hgl:101704168|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D GO:0090544//BAF-type complex GO:0003712//transcription cofactor activity;GO:0005515//protein binding GO:0048731//system development;GO:0034728//nucleosome organization;GO:0006338//chromatin remodeling;GO:0006366//transcription from RNA polymerase II promoter gi|513003135|ref|XP_004863055.1|/0/PREDICTED: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 isoform X1 [Heterocephalus glaber] 215436 3508 2.753333333 3.626666667 0.39746487 Up 0.394965963 Slc35e3 "solute carrier family 35, member E3" "K15285|1|2e-168|595|mmu:215436|solute carrier family 35, member E3" GO:0031224//intrinsic component of membrane - - gi|37497124|ref|NP_084151.2|/1.97654e-167/solute carrier family 35 member E3 [Mus musculus] 11656 1983 2.723333333 3.593333333 0.399949195 Up 0.394965963 Alas2 "aminolevulinic acid synthase 2, erythroid" K00643|1|0.0|1193|mmu:11656|5-aminolevulinate synthase [EC:2.3.1.37] GO:0019866//organelle inner membrane;GO:0044429;GO:0019866//organelle inner membrane;GO:0044429 GO:0048037//cofactor binding;GO:0016597//amino acid binding;GO:0016749//N-succinyltransferase activity;GO:0048037//cofactor binding;GO:0016597//amino acid binding;GO:0016749//N-succinyltransferase activity GO:0044703;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0007589//body fluid secretion;GO:0010038//response to metal ion;GO:0030099//myeloid cell differentiation;GO:0020027//hemoglobin metabolic process;GO:0006950//response to stress;GO:0006875//cellular metal ion homeostasis;GO:0044703;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0007589//body fluid secretion;GO:0010038//response to metal ion;GO:0030099//myeloid cell differentiation;GO:0020027//hemoglobin metabolic process;GO:0006950//response to stress;GO:0006875//cellular metal ion homeostasis "gi|387096|gb|AAA37207.1|/0/5-aminolevulinic acid synthase (EC 2.3.1.37), partial [Mus musculus]" 67867 2262.42 5.673333333 6.923333333 0.287270179 Up 0.394918951 Lrrc28 leucine rich repeat containing 28 K16175|1|5e-22|109|sko:100370729|protein scribble - - - gi|254911090|ref|NP_780333.3|/1.13687e-154/leucine-rich repeat-containing protein 28 isoform 1 [Mus musculus] 55927 1335 11.71666667 13.71 0.226666383 Up 0.394806123 Hes6 hairy and enhancer of split 6 K09087|1|6e-102|373|mmu:55927|hairy and enhancer of split 2/6/7 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0000989//transcription factor activity, transcription factor binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding" GO:0048869//cellular developmental process;GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter gi|9506777|ref|NP_062352.1|/4.81701e-101/transcription cofactor HES-6 [Mus musculus] 71067 1704 0.603333333 1.123333333 0.896758894 Up 0.394740306 4933411E08Rik RIKEN cDNA 4933411E08 gene - - - - - 101700 2400 6.253333333 5.063333333 -0.304537958 Down 0.394693294 Trim68 tripartite motif-containing 68 K12033|1|0.0|880|rno:684189|tripartite motif-containing protein 68 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0035258//steroid hormone receptor binding;GO:0019899//enzyme binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0035258//steroid hormone receptor binding;GO:0019899//enzyme binding;GO:0003824//catalytic activity GO:0016567//protein ubiquitination;GO:0030521//androgen receptor signaling pathway;GO:0016567//protein ubiquitination;GO:0030521//androgen receptor signaling pathway gi|165377144|ref|NP_932129.2|/0/E3 ubiquitin-protein ligase TRIM68 isoform 1 [Mus musculus] 103694 1645 56.82 64.43333333 0.1814084 Up 0.394618075 Tmed4 transmembrane emp24 protein transport domain containing 4 K20346|1|4e-129|464|mmu:103694|p24 family protein alpha GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0060089 GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045184//establishment of protein localization gi|19527236|ref|NP_598781.1|/3.61485e-128/transmembrane emp24 domain-containing protein 4 precursor [Mus musculus] 381148 4849 32.34333333 36.83666667 0.187674147 Up 0.394533454 Prob1 proline rich basic protein 1 - - - - gi|74222035|dbj|BAE26839.1|/0/unnamed protein product [Mus musculus] 12534 2860 0.323333333 0.76 1.232977172 Up 0.394448832 Cdk1 cyclin-dependent kinase 1 K02087|1|4e-169|598|mmu:12534|cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23] GO:0031981//nuclear lumen;GO:0005819//spindle;GO:0044444//cytoplasmic part GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0031072//heat shock protein binding "GO:0010467//gene expression;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0034614//cellular response to reactive oxygen species;GO:0006915//apoptotic process;GO:0014037//Schwann cell differentiation;GO:0007010//cytoskeleton organization;GO:0008284//positive regulation of cell proliferation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0048870//cell motility;GO:0010243//response to organonitrogen compound;GO:0009790//embryo development;GO:0000087//mitotic M phase;GO:0006935//chemotaxis;GO:0000060//protein import into nucleus, translocation;GO:0007568//aging;GO:0031572//G2 DNA damage checkpoint;GO:0000741//karyogamy;GO:0007264//small GTPase mediated signal transduction;GO:0006260//DNA replication;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0010038//response to metal ion;GO:0034502//protein localization to chromosome;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0065003;GO:0038127//ERBB signaling pathway;GO:0051276//chromosome organization;GO:0000165//MAPK cascade;GO:0097305//response to alcohol;GO:0006468//protein phosphorylation;GO:0009611//response to wounding;GO:0009887//organ morphogenesis" gi|31542366|ref|NP_031685.2|/3.16032e-168/cyclin-dependent kinase 1 [Mus musculus] 77605 1636 22.86666667 26.21333333 0.197054745 Up 0.394430027 H2afv "H2A histone family, member V" K11251|1|1e-54|216|lcm:102361001|histone H2A - - - - 83704 3315 1.243333333 1.883333333 0.599075237 Up 0.394411223 Slc12a9 "solute carrier family 12 (potassium/chloride transporters), member 9" "K14429|1|0.0|1489|mmu:83704|solute carrier family 12 (potassium/chloride transporters), member 9" GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763 gi|281371456|ref|NP_113583.2|/0/solute carrier family 12 member 9 [Mus musculus] 233802 2701 7.383333333 8.86 0.263034406 Up 0.394345406 Thumpd1 THUMP domain containing 1 K06963|1|0.0|700|mmu:233802|tRNA acetyltransferase TAN1 - GO:0003676//nucleic acid binding - gi|21704176|ref|NP_663560.1|/0/THUMP domain-containing protein 1 [Mus musculus] 56075 1638 10.29666667 8.686666667 -0.245302787 Down 0.394326601 Pdss1 "prenyl (solanesyl) diphosphate synthase, subunit 1" K12504|1|0.0|818|rno:100364990|decaprenyl-diphosphate synthase subunit 1 [EC:2.5.1.91] GO:0043231//intracellular membrane-bounded organelle "GO:0043169//cation binding;GO:0046983//protein dimerization activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups" GO:0006720//isoprenoid metabolic process;GO:0051262//protein tetramerization;GO:0006743//ubiquinone metabolic process gi|564320297|ref|XP_002725353.2|/0/PREDICTED: decaprenyl-diphosphate synthase subunit 1 isoform X1 [Rattus norvegicus] 16822 3348 1.083333333 1.696666667 0.647225938 Up 0.394307796 Lcp2 lymphocyte cytosolic protein 2 K07361|1|0.0|904|mmu:16822|lymphocyte cytosolic protein 2 GO:0044444//cytoplasmic part GO:0005488//binding GO:0007167//enzyme linked receptor protein signaling pathway;GO:0050851//antigen receptor-mediated signaling pathway;GO:0007599//hemostasis;GO:0002274;GO:0001816//cytokine production gi|31543115|ref|NP_034826.2|/0/lymphocyte cytosolic protein 2 [Mus musculus] 213491 3279.73 31.04 35.49 0.193284017 Up 0.39420437 Szrd1 SUZ RNA binding domain containing 1 - - - - gi|831248716|ref|XP_012669158.1|/1.09235e-71/PREDICTED: SUZ domain-containing protein 1-like [Otolemur garnettii] 381438 1215 55.90333333 63.29333333 0.17911924 Up 0.394176163 Gm5148 predicted gene 5148 K02973|1|3e-74|281|ptg:102972452|small subunit ribosomal protein S23e GO:0015935//small ribosomal subunit GO:0005488//binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane "gi|281350307|gb|EFB25891.1|/1.66314e-73/hypothetical protein PANDA_004337, partial [Ailuropoda melanoleuca]" 77038 3372.37 21.98333333 25.31666667 0.203677305 Up 0.394166761 Arfgap2 ADP-ribosylation factor GTPase activating protein 2 K12493|1|0.0|903|mmu:77038|ADP-ribosylation factor GTPase-activating protein 2/3 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0006810//transport;GO:0032012//regulation of ARF protein signal transduction;GO:0045184//establishment of protein localization;GO:0006810//transport;GO:0032012//regulation of ARF protein signal transduction;GO:0045184//establishment of protein localization gi|260763917|ref|NP_076343.2|/0/ADP-ribosylation factor GTPase-activating protein 2 isoform 2 [Mus musculus] 103850 1306 11.48 13.45333333 0.228841032 Up 0.394053932 Nt5m "5',3'-nucleotidase, mitochondrial" K01081|1|6e-118|426|mmu:103850|5'-nucleotidase [EC:3.1.3.5] GO:0044429 GO:0043169//cation binding;GO:0008252//nucleotidase activity;GO:0036094//small molecule binding GO:0006259//DNA metabolic process;GO:0006213//pyrimidine nucleoside metabolic process;GO:0006244;GO:0009178;GO:0009112 "gi|20127399|ref|NP_598790.1|/4.6504e-117/5'(3')-deoxyribonucleotidase, mitochondrial precursor [Mus musculus]" 208198 3026 22.24333333 25.56333333 0.200702966 Up 0.394025725 Btbd2 BTB (POZ) domain containing 2 K10477|1|0.0|953|mmu:208198|BTB/POZ domain-containing protein 1/2 GO:0035770//ribonucleoprotein granule GO:0005488//binding - gi|163965446|ref|NP_663336.2|/0/BTB/POZ domain-containing protein 2 [Mus musculus] 231834 2652 6.216666667 7.523333333 0.275230788 Up 0.394016323 Snx8 sorting nexin 8 K17922|1|0.0|863|mmu:231834|sorting nexin-8 GO:0005769//early endosome GO:0005543//phospholipid binding GO:0016482//cytosolic transport;GO:0015031//protein transport gi|26986581|ref|NP_758481.1|/0/sorting nexin-8 [Mus musculus] 104759 1978 6.713333333 8.106666667 0.272079545 Up 0.393959908 Pld4 "phospholipase D family, member 4" K16860|1|0.0|966|mmu:104759|phospholipase D3/4 [EC:3.1.4.4] GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0004620//phospholipase activity GO:0006629//lipid metabolic process gi|30725764|ref|NP_849242.1|/0/phospholipase D4 [Mus musculus] 231655 2124 2.58 3.426666667 0.409434793 Up 0.393800068 Oasl1 2'-5' oligoadenylate synthetase-like 1 K14608|1|0.0|1015|mmu:231655|2'-5'-oligoadenylate synthase-like protein GO:0031981//nuclear lumen GO:0032550;GO:0003723//RNA binding;GO:0070566//adenylyltransferase activity GO:0019079//viral genome replication;GO:0006952//defense response;GO:0051707//response to other organism;GO:0002252 gi|74178268|dbj|BAE29916.1|/0/unnamed protein product [Mus musculus] 239985 11325 6.376666667 5.193333333 -0.29614164 Down 0.393753056 Arid1b AT rich interactive domain 1B (SWI-like) K11653|1|0.0|2711|mmu:239985|AT-rich interactive domain-containing protein 1 - - - gi|145553997|ref|NP_001078824.1|/0/AT-rich interactive domain-containing protein 1B [Mus musculus] 245007 4091 1.546666667 0.96 -0.688055994 Down 0.393659032 Zbtb38 zinc finger and BTB domain containing 38 K10510|1|0.0|2296|mmu:245007|zinc finger and BTB domain-containing protein 38 GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006366//transcription from RNA polymerase II promoter gi|568961525|ref|XP_006511252.1|/0/PREDICTED: zinc finger and BTB domain-containing protein 38 isoform X2 [Mus musculus] 98685 2681 11.27 13.23 0.231325546 Up 0.393630825 Trmt1l tRNA methyltransferase 1 like K00555|1|6e-20|102|spu:585741|tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216] GO:0044464 GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0008170//N-methyltransferase activity GO:0006399//tRNA metabolic process;GO:0044707;GO:0007626//locomotory behavior gi|166988112|sp|A2RSY6.1|TRM1L_MOUSE/0/RecName: Full=TRMT1-like protein 78412 3413.4 11.44 13.39666667 0.227787025 Up 0.393630825 3110062M04Rik RIKEN cDNA 3110062M04 gene - GO:0044424;GO:0044424 - - gi|37574062|ref|NP_932103.1|/2.57698e-64/transmembrane protein 140 [Mus musculus] 381290 8140.15 4.286666667 3.336666667 -0.361448668 Down 0.393565008 Atp2b4 "ATPase, Ca++ transporting, plasma membrane 4" "K05850|1|0.0|2251|mmu:381290|Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]" - - - - 64136 1118 3.32 4.273333333 0.364178615 Up 0.393565008 Sdf2l1 stromal cell-derived factor 2-like 1 K15692|1|1e-06|56.6|tsp:Tsp_05947|E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27] - - - gi|11612505|ref|NP_071719.1|/4.8444e-101/stromal cell-derived factor 2-like protein 1 precursor [Mus musculus] 114606 2015 3.246666667 2.423333333 -0.421966408 Down 0.393555606 Tle6 transducin-like enhancer of split 6 K04497|1|2e-43|180|aag:AaeL_AAEL010433|groucho GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex - - gi|16716583|ref|NP_444484.1|/0/transducin-like enhancer protein 6 [Mus musculus] 66071 1497 25.64333333 22.36666667 -0.197233542 Down 0.393480387 Ethe1 ethylmalonic encephalopathy 1 K17725|1|2e-137|491|mmu:66071|sulfur dioxygenase [EC:1.13.11.18] GO:0044429;GO:0031981//nuclear lumen GO:0003824//catalytic activity;GO:0043169//cation binding - "gi|12963539|ref|NP_075643.1|/1.42492e-136/persulfide dioxygenase ETHE1, mitochondrial precursor [Mus musculus]" 67109 1899 16.51333333 19.13 0.212205506 Up 0.393442777 Zfp787 zinc finger protein 787 K09228|1|3e-68|262|gja:107106639|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|568946454|ref|XP_006540374.1|/0/PREDICTED: zinc finger protein 787 isoform X2 [Mus musculus] 13179 1877.42 231.0266667 259.76 0.169119903 Up 0.393433375 Dcn decorin K04660|1|0.0|716|mmu:13179|decorin - - - - 70335 2033.19 5.44 4.36 -0.319278516 Down 0.393405168 Reep6 receptor accessory protein 6 K17279|1|8e-106|244|ngi:103737322|receptor expression-enhancing protein 5/6 - - - - 19332 722 16.78666667 19.4 0.20874087 Up 0.393245327 Rab20 "RAB20, member RAS oncogene family" K07911|1|2e-132|473|mmu:19332|Ras-related protein Rab-20 GO:0030139//endocytic vesicle GO:0032550 GO:0035556//intracellular signal transduction;GO:0006906//vesicle fusion;GO:0051452//intracellular pH reduction;GO:0045184//establishment of protein localization gi|45593126|ref|NP_035357.1|/1.55267e-131/ras-related protein Rab-20 [Mus musculus] 100328588 2320 0.913333333 1.49 0.706098938 Up 0.393132498 Gm21948 "predicted gene, 21948" K03334|1|0.0|1199|mmu:100328588|L-amino-acid oxidase [EC:1.4.3.2] GO:0000323//lytic vacuole - GO:0006520//cellular amino acid metabolic process gi|283484016|ref|NP_001164495.1|/0/Nup62-Il4i1 protein precursor [Mus musculus] 53893 1590 3.816666667 4.823333333 0.337717324 Up 0.393094889 Nudt5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 K13987|1|8e-117|423|mmu:53893|ADP-sugar pyrophosphatase / 8-oxo-dGDP phosphatase [EC:3.6.1.13 3.6.1.58 3.6.1.-] - GO:0046872//metal ion binding;GO:0003723//RNA binding;GO:0016462//pyrophosphatase activity GO:0009134//nucleoside diphosphate catabolic process gi|568912477|ref|XP_006497573.1|/8.48181e-127/PREDICTED: ADP-sugar pyrophosphatase isoform X2 [Mus musculus] 110094 4481.28 4.776666667 3.763333333 -0.343993123 Down 0.393094889 Phka2 phosphorylase kinase alpha 2 K07190|1|0.0|2439|mmu:110094|phosphorylase kinase alpha/beta subunit GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane "GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006796//phosphate-containing compound metabolic process;GO:0006073//cellular glucan metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006073//cellular glucan metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006073//cellular glucan metabolic process "gi|295424152|ref|NP_001171349.1|/0/phosphorylase b kinase regulatory subunit alpha, liver isoform isoform b [Mus musculus]" 27984 2381 21.48 24.73 0.203268246 Up 0.393076084 Efhd2 EF hand domain containing 2 K01311|1|8e-31|138|apla:101795575|chymotrypsin C [EC:3.4.21.2] GO:0016020//membrane GO:0046872//metal ion binding - gi|31981086|ref|NP_080270.2|/9.22443e-94/EF-hand domain-containing protein D2 [Mus musculus] 74143 5954.3 25.51 22.26 -0.196609306 Down 0.393076084 Opa1 optic atrophy 1 K17079|1|0.0|1786|mmu:74143|optic atrophy protein 1 [EC:3.6.5.5] GO:0043005//neuron projection;GO:0005743//mitochondrial inner membrane;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0005743//mitochondrial inner membrane;GO:0031224//intrinsic component of membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0014020;GO:0010823//negative regulation of mitochondrion organization;GO:0050953//sensory perception of light stimulus;GO:0007569//cell aging;GO:0097193//intrinsic apoptotic signaling pathway;GO:0007006//mitochondrial membrane organization;GO:0014020;GO:0010823//negative regulation of mitochondrion organization;GO:0050953//sensory perception of light stimulus;GO:0007569//cell aging;GO:0097193//intrinsic apoptotic signaling pathway;GO:0007006//mitochondrial membrane organization "gi|312836758|ref|NP_001186106.1|/0/dynamin-like 120 kDa protein, mitochondrial isoform 1 precursor [Mus musculus]" 69454 799 1.14 0.62 -0.878693704 Down 0.393076084 Clic3 chloride intracellular channel 3 K05023|1|3e-135|483|mmu:69454|chloride intracellular channel protein 3 GO:0043231//intracellular membrane-bounded organelle;GO:0034702//ion channel complex GO:0005488//binding;GO:0005254//chloride channel activity GO:0015698//inorganic anion transport;GO:0034220//ion transmembrane transport;GO:0007154//cell communication gi|27229085|ref|NP_081361.1|/2.4334e-134/chloride intracellular channel protein 3 [Mus musculus] 107350 790 11.18333333 13.12333333 0.230783946 Up 0.392906841 AW112010 expressed sequence AW112010 - - - - gi|148709456|gb|EDL41402.1|/7.7954e-37/mCG12906 [Mus musculus] 12450 3501 233.6433333 207.62 -0.170362448 Down 0.392888036 Ccng1 cyclin G1 K10145|1|5e-166|588|mmu:12450|cyclin G1 GO:0043005//neuron projection;GO:0044297//cell body;GO:0044444//cytoplasmic part GO:0005515//protein binding GO:0007417//central nervous system development;GO:0031572//G2 DNA damage checkpoint;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0006915//apoptotic process;GO:0009719;GO:0040007//growth;GO:0000087//mitotic M phase gi|6753314|ref|NP_033961.1|/4.10916e-165/cyclin-G1 [Mus musculus] 27275 3974 1.66 2.36 0.507603618 Up 0.392831622 Nufip1 nuclear fragile X mental retardation protein interacting protein 1 K17337|1|7e-10|69.7|fca:101090941|cellular retinoic acid-binding protein 1 GO:0005840//ribosome;GO:0043234//protein complex;GO:0044456;GO:0000790//nuclear chromatin;GO:0034399//nuclear periphery GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0000491//small nucleolar ribonucleoprotein complex assembly;GO:0006366//transcription from RNA polymerase II promoter gi|7305335|ref|NP_038773.1|/0/nuclear fragile X mental retardation-interacting protein 1 [Mus musculus] 81630 2680 13.32 15.50333333 0.218984357 Up 0.392812817 Zbtb22 zinc finger and BTB domain containing 22 K10502|1|0.0|910|mmu:81630|zinc finger and BTB domain-containing protein 22 GO:0005622//intracellular GO:0046872//metal ion binding "GO:0006351//transcription, DNA-templated" gi|74204602|dbj|BAE35372.1|/0/unnamed protein product [Mus musculus] 277854 7113.95 4.126666667 3.203333333 -0.365402978 Down 0.392803415 Depdc5 DEP domain containing 5 K20404|1|0.0|2045|mmu:277854|DEP domain-containing protein 5 - - - gi|282847363|ref|NP_808454.2|/0/DEP domain-containing protein 5 isoform 2 [Mus musculus] 68632 2792 11.36 9.633333333 -0.237855843 Down 0.392709391 Myct1 myc target 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - - gi|880862699|ref|XP_005065952.2|/8.79206e-107/PREDICTED: myc target protein 1 [Mesocricetus auratus] 15212 1922 9.613333333 11.34 0.238311976 Up 0.392709391 Hexb hexosaminidase B K12373|1|0.0|1013|mmu:15212|hexosaminidase [EC:3.2.1.52] GO:0030141//secretory granule;GO:0005764//lysosome GO:0004563//beta-N-acetylhexosaminidase activity;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding GO:0007338//single fertilization;GO:0022604//regulation of cell morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0009311//oligosaccharide metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0007033//vacuole organization;GO:0001573//ganglioside metabolic process;GO:0050954//sensory perception of mechanical stimulus;GO:0008347//glial cell migration;GO:0006790//sulfur compound metabolic process;GO:0007619//courtship behavior;GO:0007292//female gamete generation;GO:0019222//regulation of metabolic process;GO:0008366//axon ensheathment;GO:1901071;GO:0006644//phospholipid metabolic process;GO:0010876//lipid localization;GO:0006875//cellular metal ion homeostasis;GO:0050905//neuromuscular process;GO:0044708//single-organism behavior;GO:0019538//protein metabolic process gi|6754186|ref|NP_034552.1|/0/beta-hexosaminidase subunit beta precursor [Mus musculus] 24012 2424 0.463333333 0.93 1.005180239 Up 0.392671782 Rgs7 regulator of G protein signaling 7 K16449|1|0.0|921|cge:100773500|regulator of G-protein signaling GO:0043231//intracellular membrane-bounded organelle;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0030425//dendrite;GO:0030425//dendrite;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex GO:0060089;GO:0008047//enzyme activator activity;GO:0008047//enzyme activator activity;GO:0005515//protein binding GO:0043087//regulation of GTPase activity;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway gi|312222673|ref|NP_001185932.1|/0/regulator of G-protein signaling 7 isoform 2 [Mus musculus] 242894 2108.97 18.99666667 16.41333333 -0.210878031 Down 0.392643574 Actr3b ARP3 actin-related protein 3B K18584|1|0.0|784|mmu:242894|actin-related protein 3 GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0032550 GO:0045010//actin nucleation;GO:0045010//actin nucleation gi|52345394|ref|NP_001004365.1|/0/actin-related protein 3B isoform 1 [Mus musculus] 382421 558 0.01 0.263333333 4.718818247 Up 0.392596562 Gm5176 high mobility group box 2 pseudogene K10802|1|3e-54|137|rro:104665311|high mobility group protein B1;K11295|5|5e-42|122|dre:641484|high mobility group protein B2 - - - gi|585179423|ref|XP_006741391.1|/4.7944e-54/PREDICTED: high mobility group protein B1-like [Leptonychotes weddellii] 78202 375 0.01 0.26 4.700439718 Up 0.392596562 4930557K07Rik RIKEN cDNA 4930557K07 gene - - - - - 75579 788 0.766666667 1.313333333 0.776561769 Up 0.39258716 2310034G01Rik RIKEN cDNA 2310034G01 gene - - - - gi|26342210|dbj|BAC34767.1|/7.27937e-43/unnamed protein product [Mus musculus] 234371 2970.12 29.54333333 33.79666667 0.194048349 Up 0.392540148 Tmem161a transmembrane protein 161A - GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane - GO:0033993//response to lipid;GO:0009411//response to UV;GO:0006979//response to oxidative stress;GO:0006281//DNA repair;GO:0006915//apoptotic process;GO:0033993//response to lipid;GO:0009411//response to UV;GO:0006979//response to oxidative stress;GO:0006281//DNA repair;GO:0006915//apoptotic process;GO:0033993//response to lipid;GO:0009411//response to UV;GO:0006979//response to oxidative stress;GO:0006281//DNA repair;GO:0006915//apoptotic process "gi|148696843|gb|EDL28790.1|/0/transmembrane protein 161A, isoform CRA_a, partial [Mus musculus]" 106583 4892 8.77 7.316666667 -0.261390309 Down 0.392483734 Scaf8 SR-related CTD-associated factor 8 K13191|1|0.0|1242|mmu:106583|RNA-binding protein 16 GO:0034399//nuclear periphery GO:0003676//nucleic acid binding;GO:0070063//RNA polymerase binding "GO:0006351//transcription, DNA-templated;GO:0006396//RNA processing" "gi|148669693|gb|EDL01640.1|/0/mCG121289, isoform CRA_a [Mus musculus]" 107753 607 0.34 0.78 1.197939378 Up 0.392464929 Lgals2 "lectin, galactose-binding, soluble 2" K10090|1|3e-72|273|mmu:107753|galectin-2 - - - - 73124 4551 5.136666667 4.093333333 -0.327556301 Down 0.392408515 Golim4 golgi integral membrane protein 4 K02599|1|2e-27|127|bfo:BRAFLDRAFT_86173|Notch;K19607|2|4e-10|70.5|apla:101793936|X-linked retinitis pigmentosa GTPase regulator;K15174|5|7e-08|63.2|spu:580362|RNA polymerase II-associated factor 1 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0051234//establishment of localization gi|597517893|ref|NP_001277998.1|/0/Golgi integral membrane protein 4 isoform 1 [Mus musculus] 106326 4521 6.823333333 5.6 -0.285049869 Down 0.392361503 Osbpl11 oxysterol binding protein-like 11 K20465|1|0.0|1403|mmu:106326|oxysterol-binding protein-related protein 9/10/11 - GO:0008289//lipid binding GO:0051234//establishment of localization;GO:0030154//cell differentiation;GO:0010884//positive regulation of lipid storage gi|257196261|ref|NP_789810.2|/0/oxysterol-binding protein-related protein 11 [Mus musculus] 11927 501 30.06 34.28666667 0.189802644 Up 0.392323893 Atox1 antioxidant 1 copper chaperone K07213|1|6e-33|141|mmu:11927|copper chaperone - - - - 17069 1965.32 186.1966667 209.02 0.166813747 Up 0.39219226 Ly6e "lymphocyte antigen 6 complex, locus E" K06846|1|2e-62|243|mmu:17069|lymphocyte antigen 6 complex locus protein D/E/G6/H - - - - 21351 1276 49.62666667 56.25333333 0.180823032 Up 0.392164053 Taldo1 transaldolase 1 K00616|1|0.0|662|mmu:21351|transaldolase [EC:2.2.1.2] GO:0043227//membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0016744;GO:0030246//carbohydrate binding GO:0005997//xylulose metabolic process;GO:0006098//pentose-phosphate shunt;GO:0015980//energy derivation by oxidation of organic compounds;GO:0006081//cellular aldehyde metabolic process gi|33859640|ref|NP_035658.1|/0/transaldolase [Mus musculus] 76947 1083 12.99333333 11.07333333 -0.230682017 Down 0.392145248 Ndufaf6 "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6" K18163|1|0.0|656|mmu:76947|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 6 GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity GO:0010257//NADH dehydrogenase complex assembly;GO:0008152//metabolic process "gi|147906108|ref|NP_001078962.1|/0/NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 precursor [Mus musculus]" 11757 1445 173.87 196.29 0.174977649 Up 0.392088834 Prdx3 peroxiredoxin 3 K20011|1|1e-134|482|mmu:11757|peroxiredoxin 3 [EC:1.11.1.15] GO:0043234//protein complex;GO:0005768//endosome "GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016209//antioxidant activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0019900//kinase binding" GO:0030097//hemopoiesis;GO:0043066//negative regulation of apoptotic process;GO:0043549//regulation of kinase activity;GO:0042743//hydrogen peroxide metabolic process;GO:0008283//cell proliferation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0001890//placenta development;GO:0000302//response to reactive oxygen species;GO:0006996//organelle organization;GO:0044710;GO:0002237//response to molecule of bacterial origin;GO:0042391//regulation of membrane potential "gi|6680690|ref|NP_031478.1|/1.0745e-133/thioredoxin-dependent peroxide reductase, mitochondrial precursor [Mus musculus]" 65256 2707 205.11 182.7 -0.166921197 Down 0.392070029 Asb2 ankyrin repeat and SOCS box-containing 2 K10324|1|0.0|1238|mmu:65256|ankyrin repeat and SOCS box protein 2 GO:0031461//cullin-RING ubiquitin ligase complex GO:0019787//ubiquitin-like protein transferase activity GO:0042692//muscle cell differentiation;GO:0007519//skeletal muscle tissue development;GO:0016567//protein ubiquitination;GO:0007165//signal transduction gi|23956122|ref|NP_075536.1|/0/ankyrin repeat and SOCS box protein 2 [Mus musculus] 11799 2057.28 0.823333333 1.38 0.745119726 Up 0.392013615 Birc5 baculoviral IAP repeat-containing 5 K08731|1|1e-79|298|mmu:11799|baculoviral IAP repeat-containing protein 5 GO:0043231//intracellular membrane-bounded organelle;GO:0005874//microtubule;GO:0000776//kinetochore;GO:0005819//spindle;GO:0005813//centrosome;GO:0005875//microtubule associated complex;GO:0044459;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0005874//microtubule;GO:0000776//kinetochore;GO:0005819//spindle;GO:0005813//centrosome;GO:0005875//microtubule associated complex;GO:0044459;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0017016//Ras GTPase binding;GO:0042802//identical protein binding;GO:0015631//tubulin binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0017016//Ras GTPase binding;GO:0042802//identical protein binding;GO:0015631//tubulin binding;GO:0004869//cysteine-type endopeptidase inhibitor activity "GO:0007010//cytoskeleton organization;GO:0006351//transcription, DNA-templated;GO:0000075//cell cycle checkpoint;GO:0007275//multicellular organism development;GO:0043066//negative regulation of apoptotic process;GO:0044772//mitotic cell cycle phase transition;GO:0008283//cell proliferation;GO:0007096//regulation of exit from mitosis;GO:0051346//negative regulation of hydrolase activity;GO:0007067//mitotic nuclear division;GO:0008104//protein localization;GO:0006464//cellular protein modification process;GO:0031960//response to corticosteroid;GO:0050000//chromosome localization;GO:0007010//cytoskeleton organization;GO:0006351//transcription, DNA-templated;GO:0000075//cell cycle checkpoint;GO:0007275//multicellular organism development;GO:0043066//negative regulation of apoptotic process;GO:0044772//mitotic cell cycle phase transition;GO:0007096//regulation of exit from mitosis;GO:0051346//negative regulation of hydrolase activity;GO:0008104//protein localization;GO:0006464//cellular protein modification process;GO:0031960//response to corticosteroid;GO:0050000//chromosome localization" gi|59859890|ref|NP_001012273.1|/7.74778e-68/baculoviral IAP repeat-containing protein 5 isoform 3 [Mus musculus] 232947 2971 48.26333333 54.83666667 0.184213318 Up 0.391976005 Ppp1r37 "protein phosphatase 1, regulatory subunit 37" K17576|1|0.0|1078|mmu:232947|protein phosphatase 1 regulatory subunit 37 - GO:0019899//enzyme binding GO:0010921//regulation of phosphatase activity;GO:0044092//negative regulation of molecular function "gi|148691208|gb|EDL23155.1|/0/cDNA sequence BC024868, partial [Mus musculus]" 50875 3590 18.58666667 16.05 -0.211694763 Down 0.391900786 Tmod3 tropomodulin 3 K10370|1|4e-179|631|mmu:50875|tropomodulin - - - - 74307 380 0.01 0.256666667 4.68182404 Up 0.391872579 1700092M07Rik RIKEN cDNA 1700092M07 gene - - - - gi|293629242|ref|NP_001170818.1|/6.79994e-44/uncharacterized protein LOC74307 [Mus musculus] 18747 2300 171.17 192.8166667 0.17179989 Up 0.391825567 Prkaca "protein kinase, cAMP dependent, catalytic, alpha" K04345|1|0.0|702|mmu:18747|protein kinase A [EC:2.7.11.11] GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0005815//microtubule organizing center;GO:0045202//synapse;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0051018//protein kinase A binding;GO:0019900//kinase binding;GO:0032550;GO:0044389//ubiquitin-like protein ligase binding "GO:0001704//formation of primary germ layer;GO:0003006//developmental process involved in reproduction;GO:0001678//cellular glucose homeostasis;GO:0043467//regulation of generation of precursor metabolites and energy;GO:0070830//bicellular tight junction assembly;GO:0035249//synaptic transmission, glutamatergic;GO:0032870//cellular response to hormone stimulus;GO:0010498//proteasomal protein catabolic process;GO:0001649//osteoblast differentiation;GO:0006611//protein export from nucleus;GO:0007050//cell cycle arrest;GO:0006468//protein phosphorylation" gi|7110693|ref|NP_032880.1|/0/cAMP-dependent protein kinase catalytic subunit alpha isoform 1 [Mus musculus] 57357 1769 2.92 3.81 0.383822629 Up 0.391787957 Srd5a3 steroid 5 alpha-reductase 3 K12345|1|4e-146|520|mmu:57357|3-oxo-5-alpha-steroid 4-dehydrogenase 3 [EC:1.3.1.22 1.3.1.94] GO:0043231//intracellular membrane-bounded organelle;GO:0044425 "GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0033765//steroid dehydrogenase activity, acting on the CH-CH group of donors" GO:1901137//carbohydrate derivative biosynthetic process;GO:0016093;GO:0008300//isoprenoid catabolic process gi|27881427|ref|NP_065636.2|/3.56926e-145/polyprenol reductase [Mus musculus] 641376 2920 29.06 33.21 0.19258302 Up 0.391722141 Tomm40l translocase of outer mitochondrial membrane 40 homolog-like (yeast) K11518|1|1e-168|589|lve:103085750|mitochondrial import receptor subunit TOM40 GO:0032991//macromolecular complex;GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane GO:0022829//wide pore channel activity;GO:0005244//voltage-gated ion channel activity GO:0044763;GO:0045184//establishment of protein localization;GO:0006820//anion transport gi|602713955|ref|XP_007467197.1|/1.07251e-167/PREDICTED: mitochondrial import receptor subunit TOM40B isoform X1 [Lipotes vexillifer] 70726 1564 2.186666667 2.966666667 0.440109521 Up 0.391703336 Angptl6 angiopoietin-like 6 K10104|1|1e-50|203|nle:100583637|ficolin "GO:0016023//cytoplasmic, membrane-bounded vesicle" - GO:0048869//cellular developmental process gi|21699062|ref|NP_660136.1|/0/angiopoietin-related protein 6 precursor [Mus musculus] 11984 1151 172.3533333 193.3766667 0.166044525 Up 0.391693934 Atp6v0c "ATPase, H+ transporting, lysosomal V0 subunit C" K02155|1|3e-72|247|cge:100772184|V-type H+-transporting ATPase 16kDa proteolipid subunit GO:0005774//vacuolar membrane;GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0033176//proton-transporting V-type ATPase complex "GO:0044389//ubiquitin-like protein ligase binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0015077//monovalent inorganic cation transmembrane transporter activity" "GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0051452//intracellular pH reduction;GO:0035751//regulation of lysosomal lumen pH" gi|148699288|gb|EDL31235.1|/2.38785e-85/mCG22073 [Mus musculus] 11690 1031 8.383333333 9.94 0.245721858 Up 0.391684531 Alox5ap arachidonate 5-lipoxygenase activating protein K00799|1|1e-19|99.4|pss:102461405|glutathione S-transferase [EC:2.5.1.18] - - - "gi|148673917|gb|EDL05864.1|/4.00907e-83/arachidonate 5-lipoxygenase activating protein, partial [Mus musculus]" 12389 2551.28 187.5066667 167.01 -0.167007401 Down 0.391515288 Cav1 "caveolin 1, caveolae protein" K06278|1|3e-95|352|mmu:12389|caveolin 1 GO:0005783//endoplasmic reticulum;GO:0044439;GO:0012505//endomembrane system;GO:0001669//acrosomal vesicle;GO:0032991//macromolecular complex;GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane;GO:0005924//cell-substrate adherens junction;GO:0005783//endoplasmic reticulum;GO:0044439;GO:0012505//endomembrane system;GO:0001669//acrosomal vesicle;GO:0032991//macromolecular complex;GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane;GO:0005924//cell-substrate adherens junction GO:0008047//enzyme activator activity;GO:0019899//enzyme binding;GO:0005102//receptor binding;GO:0000149//SNARE binding;GO:0008047//enzyme activator activity;GO:0019899//enzyme binding;GO:0005102//receptor binding;GO:0000149//SNARE binding GO:0009887//organ morphogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0031667//response to nutrient levels;GO:0016567//protein ubiquitination;GO:0033483;GO:0002026//regulation of the force of heart contraction;GO:0006809//nitric oxide biosynthetic process;GO:0007589//body fluid secretion;GO:0043407//negative regulation of MAP kinase activity;GO:0009612//response to mechanical stimulus;GO:0030301//cholesterol transport;GO:0055092//sterol homeostasis;GO:0051259//protein oligomerization;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0006937//regulation of muscle contraction;GO:0048771//tissue remodeling;GO:0043066//negative regulation of apoptotic process;GO:0007596//blood coagulation;GO:0030182//neuron differentiation;GO:0031112;GO:0097193//intrinsic apoptotic signaling pathway;GO:0010212//response to ionizing radiation;GO:0008285//negative regulation of cell proliferation;GO:0042391//regulation of membrane potential;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0031960//response to corticosteroid;GO:0014706//striated muscle tissue development;GO:0032769//negative regulation of monooxygenase activity;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0034613//cellular protein localization;GO:0048732//gland development;GO:0051345//positive regulation of hydrolase activity;GO:0032413//negative regulation of ion transmembrane transporter activity;GO:0030509//BMP signaling pathway;GO:0030855//epithelial cell differentiation;GO:0043393//regulation of protein binding;GO:0030178//negative regulation of Wnt signaling pathway;GO:0001765//membrane raft assembly;GO:0030177//positive regulation of Wnt signaling pathway;GO:0001935//endothelial cell proliferation;GO:0019229//regulation of vasoconstriction;GO:0006631//fatty acid metabolic process;GO:0010038//response to metal ion;GO:0031623//receptor internalization;GO:0033554//cellular response to stress;GO:0031294//lymphocyte costimulation;GO:0097191//extrinsic apoptotic signaling pathway;GO:0010522//regulation of calcium ion transport into cytosol;GO:0006639//acylglycerol metabolic process;GO:0009887//organ morphogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0031667//response to nutrient levels;GO:0016567//protein ubiquitination;GO:0033483;GO:0002026//regulation of the force of heart contraction;GO:0006809//nitric oxide biosynthetic process;GO:0007589//body fluid secretion;GO:0043407//negative regulation of MAP kinase activity;GO:0009612//response to mechanical stimulus;GO:0030301//cholesterol transport;GO:0055092//sterol homeostasis;GO:0051259//protein oligomerization;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0006937//regulation of muscle contraction;GO:0048771//tissue remodeling;GO:0043066//negative regulation of apoptotic process;GO:0007596//blood coagulation;GO:0030182//neuron differentiation;GO:0031112;GO:0097193//intrinsic apoptotic signaling pathway;GO:0010212//response to ionizing radiation;GO:0008285//negative regulation of cell proliferation;GO:0042391//regulation of membrane potential;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0031960//response to corticosteroid;GO:0014706//striated muscle tissue development;GO:0032769//negative regulation of monooxygenase activity;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0034613//cellular protein localization;GO:0048732//gland development;GO:0051345//positive regulation of hydrolase activity;GO:0032413//negative regulation of ion transmembrane transporter activity;GO:0030509//BMP signaling pathway;GO:0030855//epithelial cell differentiation;GO:0043393//regulation of protein binding;GO:0030178//negative regulation of Wnt signaling pathway;GO:0001765//membrane raft assembly;GO:0030177//positive regulation of Wnt signaling pathway;GO:0001935//endothelial cell proliferation;GO:0019229//regulation of vasoconstriction;GO:0006631//fatty acid metabolic process;GO:0010038//response to metal ion;GO:0031623//receptor internalization;GO:0033554//cellular response to stress;GO:0031294//lymphocyte costimulation;GO:0097191//extrinsic apoptotic signaling pathway;GO:0010522//regulation of calcium ion transport into cytosol;GO:0006639//acylglycerol metabolic process gi|984104888|ref|XP_015343756.1|/1.70184e-101/PREDICTED: caveolin-1 [Marmota marmota marmota] 330723 2181 1.67 1.066666667 -0.646738698 Down 0.391505886 Htra4 HtrA serine peptidase 4 K08786|1|0.0|892|mmu:330723|HtrA serine peptidase 4 [EC:3.4.21.-] - GO:0019838//growth factor binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|124487143|ref|NP_001074656.1|/0/serine protease HTRA4 precursor [Mus musculus] 18400 1520 0.103333333 0.466666667 2.175086707 Up 0.391468276 Slc22a18 "solute carrier family 22 (organic cation transporter), member 18" "K08214|1|7e-168|592|mmu:18400|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 18" GO:0005737//cytoplasm;GO:0012505//endomembrane system;GO:0044459;GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0012505//endomembrane system;GO:0044459;GO:0016021//integral component of membrane GO:0044389//ubiquitin-like protein ligase binding;GO:0008509//anion transmembrane transporter activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0008509//anion transmembrane transporter activity GO:0015893//drug transport;GO:0044763;GO:0006820//anion transport;GO:0015893//drug transport;GO:0044763;GO:0006820//anion transport gi|112363086|ref|NP_001036225.1|/6.25137e-167/solute carrier family 22 member 18 [Mus musculus] 235344 3561 3.996666667 3.083333333 -0.374306388 Down 0.391458874 Sik2 salt inducible kinase 2 K16311|1|0.0|1630|mmu:235344|serine/threonine-protein kinase SIK2 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding GO:0008286//insulin receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction gi|38569497|ref|NP_848825.2|/0/serine/threonine-protein kinase SIK2 [Mus musculus] 68394 1231 2.013333333 2.766666667 0.458562787 Up 0.391430667 Ccdc163 coiled-coil domain containing 163 K19581|1|9e-06|53.9|asn:102379922|lipid phosphate phosphatase-related protein type 1/2/5 - - - gi|134053900|ref|NP_080990.2|/1.23009e-156/coiled-coil domain containing 163 [Mus musculus] 20293 537 1.943333333 2.686666667 0.467283955 Up 0.391430667 Ccl12 chemokine (C-C motif) ligand 12 K14624|1|1e-45|184|mmu:20293|C-C motif chemokine 2;K16596|5|1e-28|127|pale:102883529|C-C motif chemokine 8 GO:0044424;GO:0044297//cell body;GO:0044421 GO:0005539//glycosaminoglycan binding;GO:0048020//CCR chemokine receptor binding;GO:0005125//cytokine activity;GO:0016301//kinase activity GO:0009636//response to toxic substance;GO:0001935//endothelial cell proliferation;GO:0070555//response to interleukin-1;GO:0006915//apoptotic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0043277//apoptotic cell clearance;GO:0006996//organelle organization;GO:0007268//chemical synaptic transmission;GO:0002699//positive regulation of immune effector process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0034341//response to interferon-gamma;GO:0008347//glial cell migration;GO:0031960//response to corticosteroid;GO:0019221//cytokine-mediated signaling pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0022610;GO:0007567//parturition;GO:0010212//response to ionizing radiation;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0001101//response to acid chemical;GO:0001817//regulation of cytokine production;GO:0007186//G-protein coupled receptor signaling pathway;GO:0035747//natural killer cell chemotaxis;GO:0001525//angiogenesis;GO:0006464//cellular protein modification process;GO:0022604//regulation of cell morphogenesis;GO:0071363//cellular response to growth factor stimulus;GO:0033273//response to vitamin;GO:0042110//T cell activation;GO:0006875//cellular metal ion homeostasis;GO:0097305//response to alcohol;GO:0034612//response to tumor necrosis factor;GO:0019058//viral life cycle;GO:0032496//response to lipopolysaccharide;GO:0009887//organ morphogenesis;GO:0072683 gi|119226206|ref|NP_035461.2|/8.62026e-45/C-C motif chemokine 12 precursor [Mus musculus] 278097 2034 0.31 0.736666667 1.248743748 Up 0.39140246 Armcx6 "armadillo repeat containing, X-linked 6" - - - - - 55950 962.75 161.0966667 180.7166667 0.165802923 Up 0.391176802 Bri3 brain protein I3 K08040|1|3e-10|67.8|gga:427655|class B basic helix-loop-helix protein 8 GO:0016020//membrane;GO:0031224//intrinsic component of membrane - - gi|255683449|ref|NP_061242.3|/9.18504e-47/brain protein I3 isoform 1 [Mus musculus] 15499 2018 28.92666667 33.00333333 0.190211658 Up 0.391073376 Hsf1 heat shock factor 1 K09414|1|0.0|953|mmu:15499|heat shock transcription factor 1 GO:0032991//macromolecular complex;GO:0005634//nucleus GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:1901976//regulation of cell cycle checkpoint;GO:0001818//negative regulation of cytokine production;GO:0008283//cell proliferation;GO:0007565//female pregnancy;GO:0007126//meiotic nuclear division;GO:0048232//male gamete generation;GO:0006464//cellular protein modification process;GO:0009408//response to heat;GO:0035264//multicellular organism growth;GO:0002237//response to molecule of bacterial origin;GO:0001701//in utero embryonic development gi|33859480|ref|NP_032322.1|/0/heat shock factor protein 1 [Mus musculus] 100038591 2396 1.333333333 0.783333333 -0.767339243 Down 0.391054571 F420014N23Rik RIKEN cDNA F420014N23 gene K00920|1|4e-21|106|ngi:103742907|1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149] - - - - 84585 4351.17 32.68333333 28.61666667 -0.191699496 Down 0.391026364 Rnf123 ring finger protein 123 K12169|1|0.0|2501|mmu:84585|Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27] GO:0044424 GO:0003824//catalytic activity;GO:0046914//transition metal ion binding - gi|54027904|ref|NP_115932.1|/0/E3 ubiquitin-protein ligase RNF123 isoform 2 [Mus musculus] 12359 2551 152.4633333 171.38 0.168736434 Up 0.391016962 Cat catalase K03781|1|0.0|1103|mmu:12359|catalase [EC:1.11.1.6] - - - - 235627 8803 4.423333333 3.466666667 -0.351584842 Down 0.39100756 Nbeal2 neurobeachin-like 2 K18953|1|2e-92|344|hst:105181650|factor associated with neutral sphingomyelinase activation GO:0043231//intracellular membrane-bounded organelle - GO:0048646//anatomical structure formation involved in morphogenesis gi|254911027|ref|NP_899099.2|/0/neurobeachin-like protein 2 [Mus musculus] 11465 1925.86 152.05 170.56 0.165733527 Up 0.390904133 Actg1 "actin, gamma, cytoplasmic 1" K05692|1|0.0|761|acs:100564373|actin beta/gamma 1 - - - - 11752 1814 0.106666667 0.463333333 2.118941073 Up 0.390857121 Anxa8 annexin A8 K17096|1|0.0|647|mmu:11752|annexin A8 - GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0046872//metal ion binding;GO:0005543//phospholipid binding GO:0007599//hemostasis;GO:0007599//hemostasis gi|22165408|ref|NP_038501.2|/0/annexin A8 isoform 1 [Mus musculus] 66704 1840 4.696666667 3.703333333 -0.342812795 Down 0.390838317 Rbm4b RNA binding motif protein 4B K13187|1|0.0|640|mmu:66704|RNA-binding protein 4 - - - - 320736 2743 3.763333333 4.75 0.335916433 Up 0.390838317 Vstm4 V-set and transmembrane domain containing 4 - - - - gi|30520277|ref|NP_848906.1|/2.23999e-147/V-set and transmembrane domain-containing protein 4 precursor [Mus musculus] 68434 673.65 9.48 11.17333333 0.237100684 Up 0.39073489 1010001N08Rik RIKEN cDNA 1010001N08 gene - - - - "gi|148691039|gb|EDL22986.1|/2.68312e-38/mCG145997, isoform CRA_a, partial [Mus musculus]" 668501 6702 1.913333333 1.283333333 -0.576192291 Down 0.390687878 Zfp507 zinc finger protein 507 K09228|1|1e-26|125|bfo:BRAFLDRAFT_66688|KRAB domain-containing zinc finger protein GO:0044464 GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding - "gi|148671058|gb|EDL03005.1|/0/mCG51010, isoform CRA_a, partial [Mus musculus]" 75084 2651 7.056666667 8.476666667 0.264510193 Up 0.390659671 4930511M06Rik RIKEN cDNA 4930511M06 gene - - - - - 67443 1712 142.3433333 160.3166667 0.171549491 Up 0.390640867 Map1lc3b microtubule-associated protein 1 light chain 3 beta K10435|1|9e-64|247|mmu:67443|microtubule-associated protein 1 light chain GO:0031982//vesicle;GO:0043005//neuron projection;GO:0005774//vacuolar membrane;GO:0044297//cell body;GO:0015630//microtubule cytoskeleton GO:0015631//tubulin binding GO:0043393//regulation of protein binding;GO:0044248 "gi|149244063|pdb|2Z0E|B/4.27311e-63/Chain B, The Crystal Structure Of Human Atg4b- Lc3(1-124) Complex" 217869 3966 29.17666667 33.18666667 0.18578866 Up 0.390556245 Eif5 eukaryotic translation initiation factor 5 K03262|1|0.0|681|mmu:217869|translation initiation factor 5 GO:0044424;GO:0044424 "GO:0008135//translation factor activity, RNA binding;GO:0032550;GO:0008135//translation factor activity, RNA binding;GO:0032550" GO:0006412//translation;GO:0006412//translation gi|29893569|ref|NP_775539.1|/0/eukaryotic translation initiation factor 5 [Mus musculus] 67725 2523 10.96333333 9.28 -0.240489797 Down 0.390292978 Nudt13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 K03426|1|1e-36|157|dre:550370|NAD+ diphosphatase [EC:3.6.1.22] GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity;GO:0043169//cation binding - "gi|22478078|gb|AAH37091.1|/0/Nudt13 protein, partial [Mus musculus]" 100169 4541.53 18.47666667 16.01666667 -0.206130577 Down 0.390123735 Phactr4 phosphatase and actin regulator 4 K17585|1|0.0|972|mmu:100169|phosphatase and actin regulator 4 GO:0005622//intracellular;GO:0031252//cell leading edge;GO:0031252//cell leading edge GO:0008092//cytoskeletal protein binding;GO:0019903//protein phosphatase binding;GO:0008599//protein phosphatase type 1 regulator activity;GO:0008092//cytoskeletal protein binding;GO:0019903//protein phosphatase binding;GO:0008599//protein phosphatase type 1 regulator activity GO:0014020;GO:0007265//Ras protein signal transduction;GO:0007049//cell cycle;GO:0007229//integrin-mediated signaling pathway;GO:0007010//cytoskeleton organization;GO:0002011//morphogenesis of an epithelial sheet;GO:0048483//autonomic nervous system development;GO:0044093;GO:0014020;GO:0007265//Ras protein signal transduction;GO:0007049//cell cycle;GO:0007229//integrin-mediated signaling pathway;GO:0007010//cytoskeleton organization;GO:0002011//morphogenesis of an epithelial sheet;GO:0048483//autonomic nervous system development;GO:0044093 gi|60360150|dbj|BAD90294.1|/0/mKIAA4120 protein [Mus musculus] 100628577 82 0.563333333 1.066666667 0.921048659 Up 0.389973297 Mir5098 microRNA 5098 - - - - - 215653 4825 1.506666667 2.18 0.532967863 Up 0.38994509 Rassf2 Ras association (RalGDS/AF-6) domain family member 2 K09851|1|0.0|637|mmu:215653|Ras association domain-containing protein 2/4 GO:0043231//intracellular membrane-bounded organelle - GO:0007154//cell communication gi|50510397|dbj|BAD32184.1|/0/mKIAA0168 protein [Mus musculus] 382427 2719 3.97 4.99 0.329900808 Up 0.389888676 Best3 bestrophin 3 K13880|1|0.0|1261|mmu:382427|bestrophin-3 GO:0034702//ion channel complex GO:0005253//anion channel activity GO:0015698//inorganic anion transport gi|56090233|ref|NP_001007584.1|/0/bestrophin-3 [Mus musculus] 12790 3568 1.546666667 0.966666667 -0.678071905 Down 0.389841664 Cnga3 cyclic nucleotide gated channel alpha 3 K04950|1|0.0|1212|mmu:12790|cyclic nucleotide gated channel alpha 3 GO:0001750//photoreceptor outer segment;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0034703//cation channel complex;GO:0001750//photoreceptor outer segment;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0034703//cation channel complex GO:0060089;GO:0030551//cyclic nucleotide binding;GO:0005221//intracellular cyclic nucleotide activated cation channel activity;GO:0060089;GO:0030551//cyclic nucleotide binding;GO:0005221//intracellular cyclic nucleotide activated cation channel activity GO:0050953//sensory perception of light stimulus;GO:0046683//response to organophosphorus;GO:0048545//response to steroid hormone;GO:0042462//eye photoreceptor cell development;GO:0010038//response to metal ion;GO:0006811//ion transport;GO:0050953//sensory perception of light stimulus;GO:0046683//response to organophosphorus;GO:0048545//response to steroid hormone;GO:0042462//eye photoreceptor cell development;GO:0010038//response to metal ion;GO:0006811//ion transport gi|33859524|ref|NP_034048.1|/0/cyclic nucleotide-gated cation channel alpha-3 isoform 2 [Mus musculus] 56018 1198 23.38666667 20.34333333 -0.201130157 Down 0.389813457 Stard10 START domain containing 10 K01866|1|8e-142|505|chx:102170371|tyrosyl-tRNA synthetase [EC:6.1.1.1];K01067|2|5e-08|61.2|cge:100752768|acetyl-CoA hydrolase [EC:3.1.2.1] - - - gi|755522934|ref|XP_011240167.1|/1.63785e-174/PREDICTED: PCTP-like protein isoform X1 [Mus musculus] 16419 3304 45.46666667 51.41666667 0.177426845 Up 0.389691226 Itgb5 integrin beta 5 K06588|1|0.0|1523|mmu:16419|integrin beta 5 GO:0030139//endocytic vesicle;GO:0005924//cell-substrate adherens junction;GO:0005887//integral component of plasma membrane;GO:0030139//endocytic vesicle;GO:0005924//cell-substrate adherens junction;GO:0005887//integral component of plasma membrane GO:0005102//receptor binding;GO:0005102//receptor binding GO:0022610;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0003012//muscle system process;GO:0007166//cell surface receptor signaling pathway;GO:0032502//developmental process;GO:0022610;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0003012//muscle system process;GO:0007166//cell surface receptor signaling pathway;GO:0032502//developmental process gi|225007617|ref|NP_034710.2|/0/integrin beta-5 isoform 2 precursor [Mus musculus] 19274 5569 32.10666667 28.2 -0.187177729 Down 0.389672421 Ptprm "protein tyrosine phosphatase, receptor type, M" K05693|1|0.0|2887|mmu:19274|receptor-type tyrosine-protein phosphatase mu [EC:3.1.3.48] - - - gi|226054321|ref|NP_033010.2|/0/receptor-type tyrosine-protein phosphatase mu precursor [Mus musculus] 12122 1906 0.363333333 0.806666667 1.150678912 Up 0.389634811 Bid BH3 interacting domain death agonist K04726|1|8e-106|387|mmu:12122|BH3 interacting domain death agonist GO:0043231//intracellular membrane-bounded organelle;GO:0031301//integral component of organelle membrane;GO:0044444//cytoplasmic part GO:0044389//ubiquitin-like protein ligase binding GO:0008637//apoptotic mitochondrial changes;GO:1901990//regulation of mitotic cell cycle phase transition;GO:0007417//central nervous system development;GO:0006605//protein targeting;GO:0008283//cell proliferation;GO:0043627//response to estrogen;GO:0010822//positive regulation of mitochondrion organization;GO:0032461//positive regulation of protein oligomerization;GO:0097191//extrinsic apoptotic signaling pathway;GO:0006839//mitochondrial transport "gi|148667234|gb|EDK99650.1|/1.27367e-111/BH3 interacting domain death agonist, isoform CRA_a, partial [Mus musculus]" 12896 2366 124.3533333 139.8133333 0.16905677 Up 0.38951258 Cpt2 carnitine palmitoyltransferase 2 K08766|1|0.0|1333|mmu:12896|carnitine O-palmitoyltransferase 2 [EC:2.3.1.21] GO:0031981//nuclear lumen;GO:0019866//organelle inner membrane GO:0016406//carnitine O-acyltransferase activity GO:0015908//fatty acid transport;GO:0009062//fatty acid catabolic process "gi|162138915|ref|NP_034079.2|/0/carnitine O-palmitoyltransferase 2, mitochondrial precursor [Mus musculus]" 106042 4085 9.69 8.17 -0.246160587 Down 0.389343337 Prickle1 prickle planar cell polarity protein 1 K04511|1|0.0|1550|mmu:106042|prickle GO:0005635//nuclear envelope;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0005515//protein binding "GO:0006351//transcription, DNA-templated;GO:0014020;GO:0051892//negative regulation of cardioblast differentiation;GO:0006886//intracellular protein transport;GO:0030178//negative regulation of Wnt signaling pathway;GO:0016567//protein ubiquitination;GO:0031331" gi|84794611|ref|NP_001028389.1|/0/prickle-like protein 1 [Mus musculus] 170768 4734.27 2.756666667 3.603333333 0.386407289 Up 0.389183497 Pfkfb3 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3" "K01103|1|0.0|1070|rno:117276|6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 3  [EC:2.7.1.105 3.1.3.46]" GO:0044444//cytoplasmic part "GO:0032550;GO:0008443//phosphofructokinase activity;GO:0050308//sugar-phosphatase activity;GO:0032550;GO:0008443//phosphofructokinase activity;GO:0050308//sugar-phosphatase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0050308//sugar-phosphatase activity;GO:0032550;GO:0008443//phosphofructokinase activity;GO:0050308//sugar-phosphatase activity;GO:0032550;GO:0008443//phosphofructokinase activity;GO:0050308//sugar-phosphatase activity;GO:0032550;GO:0008443//phosphofructokinase activity;GO:0050308//sugar-phosphatase activity;GO:0032550;GO:0008443//phosphofructokinase activity;GO:0050308//sugar-phosphatase activity;GO:0032550;GO:0008443//phosphofructokinase activity;GO:0050308//sugar-phosphatase activity" GO:0007417//central nervous system development;GO:0006796//phosphate-containing compound metabolic process;GO:0006096//glycolytic process;GO:0007417//central nervous system development;GO:0006796//phosphate-containing compound metabolic process;GO:0006096//glycolytic process;GO:0006796//phosphate-containing compound metabolic process;GO:0007417//central nervous system development;GO:0006796//phosphate-containing compound metabolic process;GO:0006096//glycolytic process;GO:0007417//central nervous system development;GO:0006796//phosphate-containing compound metabolic process;GO:0006096//glycolytic process;GO:0007417//central nervous system development;GO:0044710;GO:0006796//phosphate-containing compound metabolic process;GO:0006096//glycolytic process;GO:0007417//central nervous system development;GO:0006796//phosphate-containing compound metabolic process;GO:0006096//glycolytic process;GO:0007417//central nervous system development;GO:0006796//phosphate-containing compound metabolic process;GO:0006096//glycolytic process "gi|148676065|gb|EDL08012.1|/0/mCG9572, isoform CRA_a, partial [Mus musculus]" 71712 2807 1.94 1.303333333 -0.573850546 Down 0.389183497 Dram1 DNA-damage regulated autophagy modulator 1 K01206|1|5e-08|62.8|aqu:100640753|alpha-L-fucosidase [EC:3.2.1.51] - - - gi|27229121|ref|NP_082154.2|/8.49139e-134/DNA damage-regulated autophagy modulator protein 1 [Mus musculus] 98238 2810 19.88333333 22.87666667 0.202317217 Up 0.389145887 Lrrc59 leucine rich repeat containing 59 K10882|1|7e-14|82.4|bacu:102997594|crossover junction endonuclease EME1 [EC:3.1.22.-];K19613|2|1e-09|68.2|bfo:BRAFLDRAFT_214464|leucine-rich repeat protein SHOC2 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0044446 - - "gi|148683989|gb|EDL15936.1|/8.58148e-102/leucine rich repeat containing 59, isoform CRA_b, partial [Mus musculus]" 381110 1802 3.766666667 2.9 -0.377235467 Down 0.389042461 Rmdn2 regulator of microtubule dynamics 2 - GO:0015630//microtubule cytoskeleton;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - "gi|148706540|gb|EDL38487.1|/0/expressed sequence AW061290, isoform CRA_b, partial [Mus musculus]" 100043102 2428 2.61 3.443333333 0.399756042 Up 0.388929633 4632428C04Rik RIKEN cDNA 4632428C04 gene - - - - - 72284 1959 4.576666667 5.666666667 0.308203121 Up 0.388901425 Oraov1 oral cancer overexpressed 1 K10903|1|8e-19|98.2|bfo:BRAFLDRAFT_84669|HUS1 checkpoint protein - - - gi|31980738|ref|NP_082460.2|/8.35312e-74/oral cancer-overexpressed protein 1 homolog [Mus musculus] 72148 2477 2.053333333 1.406666667 -0.545687352 Down 0.388835609 Tdrp testis development related protein - GO:0043231//intracellular membrane-bounded organelle - - gi|568953537|ref|XP_006508964.1|/1.60369e-80/PREDICTED: testis development-related protein isoform X4 [Mus musculus] 72807 2033 1.193333333 0.673333333 -0.825604295 Down 0.388826206 Zfp429 zinc finger protein 429 K09228|1|0.0|958|mmu:380855|KRAB domain-containing zinc finger protein - GO:0043169//cation binding "GO:0006351//transcription, DNA-templated;GO:0003006//developmental process involved in reproduction" "gi|148678364|gb|EDL10311.1|/0/mCG140745, isoform CRA_a, partial [Mus musculus]" 66276 654 17.62 15.21666667 -0.211561565 Down 0.388741585 1810009A15Rik RIKEN cDNA 1810009A15 gene - - - - - 70572 4598 50.24666667 44.50333333 -0.175114493 Down 0.388600549 Ipo5 importin 5 K20222|1|0.0|2169|mmu:70572|importin-5 GO:0031981//nuclear lumen;GO:0005635//nuclear envelope GO:0022892//substrate-specific transporter activity;GO:0017016//Ras GTPase binding;GO:0004857//enzyme inhibitor activity GO:0006606//protein import into nucleus gi|29789199|ref|NP_076068.1|/0/importin-5 [Mus musculus] 13200 2134 43.05666667 48.79666667 0.180545965 Up 0.388600549 Ddost dolichyl-di-phosphooligosaccharide-protein glycotransferase K12670|1|0.0|852|mmu:13200|oligosaccharyltransferase complex subunit beta GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0005789//endoplasmic reticulum membrane GO:0005488//binding;GO:0004576//oligosaccharyl transferase activity GO:0006952//defense response;GO:0046649//lymphocyte activation;GO:0006613//cotranslational protein targeting to membrane;GO:0010467//gene expression;GO:0010033//response to organic substance;GO:0006487//protein N-linked glycosylation gi|46195798|ref|NP_031864.2|/0/dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor [Mus musculus] 232976 4158.4 6.446666667 7.76 0.267503263 Up 0.388581744 Zfp574 zinc finger protein 574 "K05205|1|2e-128|463|fpg:101912657|glutamate receptor, ionotropic kainate 5;K09228|3|2e-101|374|shr:100916702|KRAB domain-containing zinc finger protein" GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|568945493|ref|XP_006539913.1|/0/PREDICTED: zinc finger protein 574 isoform X2 [Mus musculus] 71458 4710.99 8.55 7.156666667 -0.256636635 Down 0.38852533 Bcor BCL6 interacting corepressor - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0000975//regulatory region DNA binding;GO:0019899//enzyme binding;GO:0003712//transcription cofactor activity;GO:0000975//regulatory region DNA binding;GO:0019899//enzyme binding;GO:0003712//transcription cofactor activity;GO:0000975//regulatory region DNA binding;GO:0019899//enzyme binding;GO:0003712//transcription cofactor activity;GO:0000975//regulatory region DNA binding;GO:0019899//enzyme binding;GO:0003712//transcription cofactor activity;GO:0000975//regulatory region DNA binding;GO:0019899//enzyme binding GO:0010390//histone monoubiquitination;GO:0034505//tooth mineralization;GO:0006366//transcription from RNA polymerase II promoter;GO:0030279//negative regulation of ossification;GO:0007389//pattern specification process;GO:0000414//regulation of histone H3-K36 methylation;GO:0031061//negative regulation of histone methylation;GO:0010390//histone monoubiquitination;GO:0034505//tooth mineralization;GO:0006366//transcription from RNA polymerase II promoter;GO:0030279//negative regulation of ossification;GO:0007389//pattern specification process;GO:0000414//regulation of histone H3-K36 methylation;GO:0031061//negative regulation of histone methylation;GO:0010390//histone monoubiquitination;GO:0034505//tooth mineralization;GO:0006366//transcription from RNA polymerase II promoter;GO:0030279//negative regulation of ossification;GO:0007389//pattern specification process;GO:0000414//regulation of histone H3-K36 methylation;GO:0031061//negative regulation of histone methylation;GO:0010390//histone monoubiquitination;GO:0034505//tooth mineralization;GO:0006366//transcription from RNA polymerase II promoter;GO:0030279//negative regulation of ossification;GO:0007389//pattern specification process;GO:0000414//regulation of histone H3-K36 methylation;GO:0031061//negative regulation of histone methylation;GO:0010390//histone monoubiquitination;GO:0034505//tooth mineralization;GO:0006366//transcription from RNA polymerase II promoter;GO:0030279//negative regulation of ossification;GO:0007389//pattern specification process;GO:0000414//regulation of histone H3-K36 methylation;GO:0031061//negative regulation of histone methylation gi|37360460|dbj|BAC98208.1|/0/mKIAA1575 protein [Mus musculus] 94352 5186 8.383333333 6.993333333 -0.261543722 Down 0.38852533 Loxl2 lysyl oxidase-like 2 K00280|1|0.0|1604|mmu:94352|lysyl oxidase-like protein 2/3/4 [EC:1.4.3.-] GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043232 "GO:0046914//transition metal ion binding;GO:0030246//carbohydrate binding;GO:0042393//histone binding;GO:0003712//transcription cofactor activity;GO:0038024//cargo receptor activity;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor" "GO:0001525//angiogenesis;GO:0006351//transcription, DNA-templated;GO:0002062//chondrocyte differentiation;GO:0030198//extracellular matrix organization;GO:0050673//epithelial cell proliferation;GO:0044710;GO:0000904//cell morphogenesis involved in differentiation;GO:0010038//response to metal ion;GO:0006464//cellular protein modification process;GO:0006950//response to stress;GO:0016477//cell migration" gi|225579028|ref|NP_201582.2|/0/lysyl oxidase homolog 2 precursor [Mus musculus] 54343 4543 7.13 5.886666667 -0.27645114 Down 0.388515928 Atf7ip activating transcription factor 7 interacting protein - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0017111//nucleoside-triphosphatase activity;GO:0003712//transcription cofactor activity GO:0051123//RNA polymerase II transcriptional preinitiation complex assembly;GO:0006305;GO:0009154//purine ribonucleotide catabolic process gi|34328232|ref|NP_062299.2|/0/activating transcription factor 7-interacting protein 1 [Mus musculus] 12606 2636 3.71 4.68 0.335089343 Up 0.38848772 Cebpa "CCAAT/enhancer binding protein (C/EBP), alpha" "K09055|1|8e-104|380|hgl:101726330|CCAAT/enhancer binding protein (C/EBP), alpha" GO:0034399//nuclear periphery;GO:0005667//transcription factor complex "GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0000975//regulatory region DNA binding" GO:0051716//cellular response to stimulus;GO:0016125//sterol metabolic process;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0002526//acute inflammatory response;GO:0010243//response to organonitrogen compound;GO:0043583//ear development;GO:0002573//myeloid leukocyte differentiation;GO:0008283//cell proliferation;GO:0045444//fat cell differentiation;GO:0021700//developmental maturation;GO:0006996//organelle organization;GO:0030323//respiratory tube development;GO:0009887//organ morphogenesis;GO:0050794//regulation of cellular process;GO:0031960//response to corticosteroid;GO:0010226//response to lithium ion;GO:0001701//in utero embryonic development;GO:0031667//response to nutrient levels gi|566559969|ref|NP_001274443.1|/4.39839e-108/CCAAT/enhancer-binding protein alpha isoform c [Mus musculus] 27356 660 0.71 0.293333333 -1.275278002 Down 0.388412501 Insl6 insulin-like 6 K05255|1|7e-97|355|mmu:27356|relaxin - - GO:0048870//cell motility;GO:0007281//germ cell development;GO:0012501//programmed cell death;GO:0040007//growth;GO:0048232//male gamete generation;GO:0008406//gonad development gi|7305185|ref|NP_038782.1|/5.102e-96/insulin-like peptide INSL6 precursor [Mus musculus] 22643 2731 0.81 0.37 -1.130396637 Down 0.388346685 Zfp101 zinc finger protein 101 K09228|1|0.0|1322|mmu:22643|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|119120797|ref|NP_033568.2|/0/zinc finger protein 101 [Mus musculus] 20391 1738 107.3633333 120.6666667 0.168525828 Up 0.388346685 Sgca "sarcoglycan, alpha (dystrophin-associated glycoprotein)" K12565|1|0.0|749|mmu:20391|alpha-sarcoglycan - - - - 66730 1905 2.873333333 2.116666667 -0.440931277 Down 0.388280868 4921531C22Rik RIKEN cDNA 4921531C22 gene - - - - gi|148675353|gb|EDL07300.1|/1.88282e-22/mCG140081 [Mus musculus] 73130 3751 12.31333333 14.34 0.219823658 Up 0.38793298 Tmed5 transmembrane emp24 protein transport domain containing 5 K14825|1|2e-107|393|mmu:73130|p24 family protein gamma-2 GO:0044432;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane - GO:0007030//Golgi organization;GO:0045184//establishment of protein localization gi|18043634|gb|AAH20076.1|/2.09913e-106/Transmembrane emp24 protein transport domain containing 5 [Mus musculus] 214812 8602 7.57 6.27 -0.271827857 Down 0.387923577 Zfp609 zinc finger protein 609 K10847|1|1e-50|206|spu:582941|DNA-repair protein complementing XP-A cells;K06783|2|4e-14|84.7|chx:102184188|cell adhesion molecule 4 - - - gi|209447068|ref|NP_766124.2|/0/zinc finger protein 609 [Mus musculus] 67286 911 6.436666667 7.74 0.266019808 Up 0.387923577 Ift22 intraflagellar transport 22 K07935|1|2e-105|384|mmu:67286|intraflagellar transport protein 22 - - - - 320333 1720.26 2.006666667 1.363333333 -0.557662644 Down 0.387838956 D830030K20Rik RIKEN cDNA D830030K20 gene "K03844|1|2e-22|110|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - gi|755547000|ref|XP_011243064.1|/1.05646e-103/PREDICTED: alpha28-takusan isoform X2 [Mus musculus] 217721 3435 5.196666667 4.166666667 -0.318692833 Down 0.387820151 Mfsd7c major facilitator superfamily domain containing 7C "K08220|1|0.0|1075|mmu:217721|MFS transporter, FLVCR family, feline leukemia virus subgroup C receptor-related protein" GO:0031224//intrinsic component of membrane GO:0051184;GO:0046906//tetrapyrrole binding GO:0051181//cofactor transport;GO:0044763 gi|21703892|ref|NP_663422.1|/0/feline leukemia virus subgroup C receptor-related protein 2 [Mus musculus] 12832 6615 5.53 4.446666667 -0.31455522 Down 0.387801346 Col5a2 "collagen, type V, alpha 2" "K19721|1|0.0|1592|mmu:12832|collagen, type V/XI/XXIV/XXVII, alpha" - - - - 17294 2496.86 4.423333333 5.5 0.314297654 Up 0.387801346 Mest mesoderm specific transcript - GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0019915//lipid storage;GO:0033993//response to lipid;GO:0019915//lipid storage;GO:0033993//response to lipid;GO:0019915//lipid storage;GO:0033993//response to lipid gi|356582503|ref|NP_001239221.1|/0/mesoderm-specific transcript protein isoform 1 [Mus musculus] 80287 2360 4.48 5.563333333 0.312450817 Up 0.387801346 Apobec3 "apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3" K18750|1|0.0|818|mmu:80287|C->U-editing enzyme APOBEC3 [EC:3.5.4.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0046914//transition metal ion binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines" GO:0010528//regulation of transposition;GO:0002252;GO:0010528//regulation of transposition;GO:0002252 "gi|148672677|gb|EDL04624.1|/0/apolipoprotein B editing complex 3, isoform CRA_c, partial [Mus musculus]" 66990 1483.34 42.86666667 48.41666667 0.175647521 Up 0.387782542 Tmem134 transmembrane protein 134 - GO:0016020//membrane;GO:0016020//membrane - - gi|13385378|ref|NP_080165.1|/6.15349e-76/transmembrane protein 134 isoform b [Mus musculus] 70152 1883 25.84 29.56333333 0.194202876 Up 0.387688518 Mettl7a1 methyltransferase like 7A1 K07755|1|7e-06|55.1|cin:100181209|arsenite methyltransferase [EC:2.1.1.137] - GO:0016741 GO:0008152//metabolic process gi|33563290|ref|NP_081610.2|/4.01188e-142/methyltransferase-like protein 7A [Mus musculus] 27681 947 25.97 29.68666667 0.192969097 Up 0.387688518 Snf8 "SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)" K12188|1|1e-138|494|ptr:468434|ESCRT-II complex subunit VPS22 GO:0043234//protein complex;GO:0005770//late endosome GO:0005515//protein binding GO:0044763;GO:0045184//establishment of protein localization;GO:0044765//single-organism transport;GO:0006366//transcription from RNA polymerase II promoter "gi|148684061|gb|EDL16008.1|/2.47522e-142/SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae), isoform CRA_c [Mus musculus]" 13139 2842 8.796666667 10.42 0.244326428 Up 0.387622701 Dgka "diacylglycerol kinase, alpha" K00901|1|0.0|1524|mmu:13139|diacylglycerol kinase (ATP) [EC:2.7.1.107] GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0046872//metal ion binding;GO:0008289//lipid binding;GO:0016301//kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0007186//G-protein coupled receptor signaling pathway gi|31560474|ref|NP_058091.2|/0/diacylglycerol kinase alpha [Mus musculus] 72093 745 8.736666667 10.35333333 0.244940476 Up 0.387622701 2010320M18Rik RIKEN cDNA 2010320M18 gene - - - - - 13681 1897 101.0266667 113.3066667 0.165496596 Up 0.387622701 Eif4a1 eukaryotic translation initiation factor 4A1 K03257|1|0.0|707|pale:102887954|translation initiation factor 4A GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0032550;GO:0042623//ATPase activity, coupled;GO:0008135//translation factor activity, RNA binding;GO:0032550;GO:0042623//ATPase activity, coupled;GO:0008135//translation factor activity, RNA binding" "GO:0006412//translation;GO:0009887//organ morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006412//translation;GO:0009887//organ morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" "gi|224036359|pdb|3EIQ|A/0/Chain A, Crystal Structure Of Pdcd4-eif4a" 100039139 798 0.133333333 0.506666667 1.925999419 Up 0.387613299 Ccdc152 coiled-coil domain containing 152 K16551|1|3e-10|67.8|mgp:100538426|A-kinase anchor protein 9;K17589|3|7e-10|66.6|ccw:104690395|RB1-inducible coiled-coil protein 1;K20283|4|9e-10|66.2|ccw:104688883|golgin subfamily A member 4 - - - gi|260593692|ref|NP_001159535.1|/1.05553e-137/coiled-coil domain-containing protein 152 [Mus musculus] 22750 3921 1.653333333 1.06 -0.641313355 Down 0.38753808 Zfp9 zinc finger protein 9 K09228|1|0.0|981|mmu:22750|KRAB domain-containing zinc finger protein GO:0044464 GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding "GO:0006351//transcription, DNA-templated" gi|27261814|ref|NP_035893.1|/0/zinc finger protein 9 [Mus musculus] 228730 2150 29.94 26.24666667 -0.18994001 Down 0.387444056 Kiz kizuna centrosomal protein K16539|1|0.0|1138|mmu:228730|centrosomal protein kizuna GO:0005815//microtubule organizing center GO:0019900//kinase binding GO:0000226//microtubule cytoskeleton organization gi|85701800|ref|NP_001028470.1|/0/centrosomal protein kizuna [Mus musculus] 100038693 1758 0.173333333 0.55 1.665882496 Up 0.387425251 Tmem51os1 Tmem51 opposite strand 1 - - - - gi|74196634|dbj|BAE34421.1|/1.69324e-38/unnamed protein product [Mus musculus] 69017 2510 2.07 1.423333333 -0.540357199 Down 0.387415849 Prrt2 proline-rich transmembrane protein 2 - GO:0016020//membrane - - gi|156523248|ref|NP_001096033.1|/4.655e-144/proline-rich transmembrane protein 2 [Mus musculus] 74127 1774 2.07 1.42 -0.543739838 Down 0.387415849 Krt80 keratin 80 "K07605|1|0.0|821|mmu:74127|type II keratin, basic" GO:0005882//intermediate filament - - "gi|124249090|ref|NP_083046.2|/0/keratin, type II cytoskeletal 80 [Mus musculus]" 77799 2508 15.12 17.45666667 0.207319965 Up 0.387350032 Sla2 Src-like-adaptor 2 K08890|1|3e-34|149|tup:102480506|B lymphoid tyrosine kinase [EC:2.7.10.2];K05854|2|7e-34|148|clv:102084226|tyrosine-protein kinase Lyn [EC:2.7.10.2] GO:0005768//endosome;GO:0031982//vesicle;GO:0016020//membrane "GO:0030674//protein binding, bridging" GO:0019722//calcium-mediated signaling;GO:0046649//lymphocyte activation gi|124249228|ref|NP_084259.1|/1.90473e-113/src-like-adapter 2 [Mus musculus] 433813 1229 3.663333333 4.626666667 0.336816182 Up 0.387274813 Pusl1 pseudouridylate synthase-like 1 K01855|1|3e-13|79.0|xtr:394566|tRNA pseudouridine38/39 synthase [EC:5.4.99.45] - GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity GO:0006399//tRNA metabolic process gi|241896974|ref|NP_001028662.1|/1.35177e-163/tRNA pseudouridine synthase-like 1 [Mus musculus] 18074 4913 8.306666667 6.933333333 -0.26072054 Down 0.387180789 Nid2 nidogen 2 K06826|1|0.0|2718|mmu:18074|nidogen (entactin) GO:0044464;GO:0005578//proteinaceous extracellular matrix GO:0005488//binding GO:0031589//cell-substrate adhesion gi|84370361|ref|NP_032721.2|/0/nidogen-2 precursor [Mus musculus] 19185 1337.88 93.49 105.1733333 0.169884993 Up 0.386973937 Psmd4 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 4" K03029|1|6e-171|602|mmu:19185|26S proteasome regulatory subunit N10 GO:0005838//proteasome regulatory particle;GO:0005838//proteasome regulatory particle - GO:0044765//single-organism transport;GO:0019941//modification-dependent protein catabolic process;GO:0044765//single-organism transport;GO:0019941//modification-dependent protein catabolic process gi|537264904|gb|ERE90763.1|/1.47139e-174/putative PIP5K1A and PSMD4-like protein [Cricetulus griseus] 381598 4009 4.083333333 3.186666667 -0.357699226 Down 0.386842303 2610005L07Rik cadherin 11 pseudogene "K06803|1|1e-128|301|mmu:12552|cadherin 11, type 2, OB-cadherin" GO:0031224//intrinsic component of membrane;GO:0044424 GO:0046872//metal ion binding GO:0021952//central nervous system projection neuron axonogenesis;GO:0016337//single organismal cell-cell adhesion gi|148679247|gb|EDL11194.1|/1.19379e-127/cadherin 11 [Mus musculus] 210148 2156 4.476666667 5.546666667 0.309196129 Up 0.386701267 Slc30a6 "solute carrier family 30 (zinc transporter), member 6" "K14693|1|0.0|865|mmu:210148|solute carrier family 30 (zinc transporter), member 6" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity GO:0006892//post-Golgi vesicle-mediated transport;GO:0006829//zinc II ion transport;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006829//zinc II ion transport gi|31559966|ref|NP_659047.2|/0/zinc transporter 6 isoform 2 [Mus musculus] 74334 5308 10.27666667 8.676666667 -0.244159578 Down 0.386626048 Ranbp10 RAN binding protein 10 K12169|1|1e-09|69.3|aec:105154204|Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27];K13177|3|4e-09|67.4|loa:LOAG_08173|ATP-dependent RNA helicase DDX1 [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle;GO:0005874//microtubule GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0017016//Ras GTPase binding;GO:0015631//tubulin binding GO:0019222//regulation of metabolic process gi|40804757|ref|NP_665823.2|/0/ran-binding protein 10 [Mus musculus] 69310 1355 0.586666667 1.083333333 0.884864289 Up 0.386616646 Pacrg PARK2 co-regulated K03018|1|2e-74|281|cfo:105258154|DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6] GO:0044441 - GO:0007281//germ cell development "gi|149027497|gb|EDL83087.1|/1.57121e-131/similar to PACRG (predicted), isoform CRA_a [Rattus norvegicus]" 14728 1497 2.136666667 2.89 0.435707637 Up 0.386607244 Lilrb4a "leukocyte immunoglobulin-like receptor, subfamily B, member 4A" K06512|1|7e-166|586|mmu:14728|leukocyte immunoglobulin-like receptor GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|7305097|ref|NP_038560.1|/1.55591e-160/leukocyte immunoglobulin-like receptor subfamily B member 4 isoform 1 precursor [Mus musculus] 101883 1192 2.086666667 2.833333333 0.441300184 Up 0.386607244 Igflr1 IGF-like family receptor 1 - GO:0031224//intrinsic component of membrane GO:0005488//binding - gi|148692060|gb|EDL24007.1|/1.78955e-173/hypothetical protein MGC30332 [Mus musculus] 13713 4234 17.08 14.78 -0.208661705 Down 0.386249953 Elk3 "ELK3, member of ETS oncogene family" K09430|1|2e-162|576|mmu:13713|ETS domain-containing protein Elk-3 (SRF accessory protein 2) GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0044212//transcription regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003712//transcription cofactor activity;GO:0044212//transcription regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003712//transcription cofactor activity;GO:0044212//transcription regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003712//transcription cofactor activity;GO:0044212//transcription regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0009611//response to wounding;GO:0006351//transcription, DNA-templated;GO:0009611//response to wounding;GO:0006351//transcription, DNA-templated;GO:0009611//response to wounding;GO:0006351//transcription, DNA-templated;GO:0009611//response to wounding;GO:0006351//transcription, DNA-templated" "gi|148689601|gb|EDL21548.1|/1.67502e-114/ELK3, member of ETS oncogene family, isoform CRA_a [Mus musculus]" 56632 3662.72 18.55 21.35 0.202816883 Up 0.386231148 Sphk2 sphingosine kinase 2 K04718|1|0.0|1103|mmu:56632|sphingosine kinase [EC:2.7.1.91] GO:0000323//lytic vacuole;GO:0000323//lytic vacuole;GO:0000323//lytic vacuole GO:0032550;GO:0001727//lipid kinase activity;GO:0032550;GO:0001727//lipid kinase activity;GO:0032550;GO:0001727//lipid kinase activity GO:0007417//central nervous system development;GO:0044703;GO:0006066//alcohol metabolic process;GO:0006668//sphinganine-1-phosphate metabolic process;GO:0006915//apoptotic process;GO:0001944//vasculature development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0007417//central nervous system development;GO:0044703;GO:0006066//alcohol metabolic process;GO:0006668//sphinganine-1-phosphate metabolic process;GO:0006915//apoptotic process;GO:0001944//vasculature development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0007417//central nervous system development;GO:0044703;GO:0006066//alcohol metabolic process;GO:0006668//sphinganine-1-phosphate metabolic process;GO:0006915//apoptotic process;GO:0001944//vasculature development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation gi|74207344|dbj|BAE30855.1|/0/unnamed protein product [Mus musculus] 59009 5199 2.32 1.636666667 -0.503364282 Down 0.386184136 Sh3rf1 SH3 domain containing ring finger 1 K12171|1|0.0|1533|mmu:59009|E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0031252//cell leading edge;GO:0044444//cytoplasmic part GO:0032947//protein complex scaffold;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0012502//induction of programmed cell death;GO:0007254//JNK cascade;GO:0032446//protein modification by small protein conjugation;GO:0097191//extrinsic apoptotic signaling pathway gi|50510955|dbj|BAD32463.1|/0/mKIAA1494 protein [Mus musculus] 213084 2147.41 2.316666667 1.636666667 -0.501289953 Down 0.386184136 Cdkl3 cyclin-dependent kinase-like 3 K08824|1|1e-166|588|rno:103694901|cyclin-dependent kinase-like [EC:2.7.11.22] GO:0044424;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0044424;GO:0044424;GO:0044424 GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|262263406|ref|NP_001160129.1|/0/cyclin-dependent kinase-like 3 isoform 6 [Mus musculus] 66200 903.02 8.866666667 10.46 0.238419107 Up 0.38611832 Commd6 COMM domain containing 6 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0008134//transcription factor binding;GO:0008134//transcription factor binding GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity "gi|148668152|gb|EDL00482.1|/1.70928e-41/mCG113792, isoform CRA_b, partial [Mus musculus]" 13660 3182 93.32666667 82.79666667 -0.172716681 Down 0.385817443 Ehd1 EH-domain containing 1 K12483|1|0.0|1042|mcf:101926234|EH domain-containing protein 1 "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005769//early endosome;GO:0010008//endosome membrane" GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0046872//metal ion binding GO:0016192//vesicle-mediated transport;GO:0055092//sterol homeostasis;GO:0051259//protein oligomerization;GO:0044765//single-organism transport;GO:0007599//hemostasis;GO:0034381//plasma lipoprotein particle clearance;GO:0015031//protein transport;GO:0010878//cholesterol storage "gi|22477515|gb|AAH37094.1|/0/EH-domain containing 1, partial [Mus musculus]" 11615 2093 6.27 7.543333333 0.266736736 Up 0.385798639 Gm4737 predicted gene 4737 K01251|1|0.0|863|mmu:11615|adenosylhomocysteinase [EC:3.3.1.1] - - - - 103213 2867 1.936666667 2.656666667 0.456041561 Up 0.385789236 Traf3ip2 TRAF3 interacting protein 2 - - - - - 69546 1524 25.47666667 29.02333333 0.188036693 Up 0.385779834 Mapk1ip1 mitogen-activated protein kinase 1 interacting protein 1 "K19720|1|3e-07|59.3|soc:105196400|collagen, type III, alpha;K06237|2|6e-06|54.7|pxy:105386157|collagen, type IV, alpha;K12185|3|8e-06|54.3|gfr:102037447|ESCRT-I complex subunit VPS37" GO:0043232;GO:0043232 GO:0005515//protein binding;GO:0005515//protein binding GO:0022403;GO:0032502//developmental process;GO:0022403;GO:0032502//developmental process gi|24158486|ref|NP_081391.1|/8.88279e-118/MAPK-interacting and spindle-stabilizing protein [Mus musculus] 74996 5587.04 21.55333333 18.78666667 -0.198201896 Down 0.3856482 Usp47 ubiquitin specific peptidase 47 K11857|1|0.0|2608|mmu:74996|ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12] GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex GO:0019783//ubiquitin-like protein-specific protease activity;GO:0019904//protein domain specific binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0019904//protein domain specific binding "GO:0006351//transcription, DNA-templated;GO:0042221//response to chemical;GO:0016579//protein deubiquitination;GO:0006915//apoptotic process;GO:0009411//response to UV;GO:0019941//modification-dependent protein catabolic process;GO:0016049//cell growth;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006281//DNA repair;GO:0006351//transcription, DNA-templated;GO:0042221//response to chemical;GO:0016579//protein deubiquitination;GO:0006915//apoptotic process;GO:0009411//response to UV;GO:0019941//modification-dependent protein catabolic process;GO:0016049//cell growth;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006281//DNA repair" gi|48928014|ref|NP_598519.2|/0/ubiquitin carboxyl-terminal hydrolase 47 isoform 2 [Mus musculus] 75815 1734 2.523333333 3.333333333 0.401634795 Up 0.385535372 4930470H14Rik RIKEN cDNA 4930470H14 gene K04613|1|2e-11|73.2|rno:297590|vomeronasal 2 receptor - - - - 20341 1685 82.77 93.09666667 0.169621555 Up 0.385516567 Selenbp1 selenium binding protein 1 K17285|1|0.0|983|mmu:20341|selenium-binding protein 1 GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen GO:0005488//binding GO:0045184//establishment of protein localization;GO:0045444//fat cell differentiation gi|22164798|ref|NP_033176.2|/0/selenium-binding protein 1 [Mus musculus] 70348 1828 0.4 0.843333333 1.076102979 Up 0.385460153 Ube2cbp ubiquitin-conjugating enzyme E2C binding protein K09228|1|9e-09|64.7|tca:103312614|KRAB domain-containing zinc finger protein GO:0044424 GO:0003824//catalytic activity GO:0032446//protein modification by small protein conjugation gi|110625767|ref|NP_081670.1|/0/E3 ubiquitin-protein ligase E3D [Mus musculus] 108645 1893.5 38.28666667 43.36 0.179522696 Up 0.385384934 Mat2b "methionine adenosyltransferase II, beta" K00789|1|0.0|683|mmu:108645|S-adenosylmethionine synthetase [EC:2.5.1.6] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0030234//enzyme regulator activity;GO:0036094//small molecule binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0030234//enzyme regulator activity;GO:0036094//small molecule binding;GO:0048037//cofactor binding" GO:0044710;GO:0009108//coenzyme biosynthetic process;GO:0033692//cellular polysaccharide biosynthetic process;GO:0044710;GO:0009108//coenzyme biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0006807//nitrogen compound metabolic process;GO:0033692//cellular polysaccharide biosynthetic process gi|19527234|ref|NP_598778.1|/0/methionine adenosyltransferase 2 subunit beta isoform 1 [Mus musculus] 100042807 2419 0.25 0.01 -4.64385619 Down 0.385366129 Eif3j2 "eukaryotic translation initiation factor 3, subunit J2" K03245|1|7e-83|311|mmu:78655|translation initiation factor 3 subunit J - - - gi|635057503|ref|XP_007962947.1|/2.86089e-82/PREDICTED: eukaryotic translation initiation factor 3 subunit J [Chlorocebus sabaeus] 66341 1305 0.01 0.25 4.64385619 Up 0.385366129 Eid3 EP300 interacting inhibitor of differentiation 3 - GO:0043231//intracellular membrane-bounded organelle;GO:0000793//condensed chromosome GO:0005515//protein binding "GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006351//transcription, DNA-templated" gi|125988414|ref|NP_079775.2|/0/EP300-interacting inhibitor of differentiation 3 [Mus musculus] 78444 955 0.01 0.25 4.64385619 Up 0.385366129 Pgpep1l pyroglutamyl-peptidase I-like K01304|1|3e-46|187|mgp:104912870|pyroglutamyl-peptidase [EC:3.4.19.3] - - - gi|568948760|ref|XP_006541378.1|/6.01572e-98/PREDICTED: pyroglutamyl-peptidase 1-like protein isoform X1 [Mus musculus] 212503 1737 2.016666667 2.75 0.447458977 Up 0.385366129 Paox polyamine oxidase (exo-N4-amino) K00308|1|0.0|1020|mmu:212503|N1-acetylpolyamine oxidase [EC:1.5.3.13] GO:0044439 "GO:0016647//oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor;GO:0005515//protein binding" GO:0006598//polyamine catabolic process;GO:0044710;GO:0006596//polyamine biosynthetic process;GO:0010557//positive regulation of macromolecule biosynthetic process gi|28173566|ref|NP_722478.2|/0/peroxisomal N(1)-acetyl-spermine/spermidine oxidase [Mus musculus] 11540 2604 10.03666667 11.78666667 0.231875567 Up 0.385337922 Adora2a adenosine A2a receptor K04266|1|0.0|719|mmu:11540|adenosine receptor A2a GO:0031224//intrinsic component of membrane;GO:0032589//neuron projection membrane;GO:0043234//protein complex;GO:0044327//dendritic spine head;GO:0043229//intracellular organelle;GO:0044297//cell body;GO:0097060//synaptic membrane GO:0004930//G-protein coupled receptor activity;GO:0046983//protein dimerization activity;GO:0042805//actinin binding;GO:0035256//G-protein coupled glutamate receptor binding "GO:0006954//inflammatory response;GO:0042753//positive regulation of circadian rhythm;GO:0046631//alpha-beta T cell activation;GO:0001964//startle response;GO:0007631//feeding behavior;GO:0014075//response to amine;GO:0035809;GO:0035588;GO:0051899//membrane depolarization;GO:0031175//neuron projection development;GO:0009967//positive regulation of signal transduction;GO:0006351//transcription, DNA-templated;GO:0035249//synaptic transmission, glutamatergic;GO:0001933//negative regulation of protein phosphorylation;GO:0035813//regulation of renal sodium excretion;GO:0014047//glutamate secretion;GO:0044708//single-organism behavior;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0050880//regulation of blood vessel size;GO:0043114//regulation of vascular permeability;GO:0008283//cell proliferation;GO:0040011//locomotion;GO:0043066//negative regulation of apoptotic process;GO:0048243//norepinephrine secretion;GO:0006816//calcium ion transport;GO:0060078//regulation of postsynaptic membrane potential;GO:0006171//cAMP biosynthetic process;GO:0001956//positive regulation of neurotransmitter secretion;GO:0014074//response to purine-containing compound;GO:0009306//protein secretion;GO:0032228//regulation of synaptic transmission, GABAergic" gi|126517500|ref|NP_033760.2|/0/adenosine receptor A2a [Mus musculus] 13511 5771 10.22666667 11.97666667 0.227890452 Up 0.385337922 Dsg2 desmoglein 2 K07597|1|0.0|2043|mmu:13511|desmoglein 2 GO:0031224//intrinsic component of membrane;GO:0044459;GO:0005911//cell-cell junction GO:0046872//metal ion binding GO:0002027//regulation of heart rate;GO:0012501//programmed cell death;GO:0016337//single organismal cell-cell adhesion;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0022411;GO:0086065//cell communication involved in cardiac conduction gi|161016843|ref|NP_031909.2|/0/desmoglein-2 preproprotein [Mus musculus] 107569 1568.88 27.87333333 24.36666667 -0.193976637 Down 0.385328519 Nt5c3 "5'-nucleotidase, cytosolic III" K01081|1|1e-173|612|mmu:107569|5'-nucleotidase [EC:3.1.3.5] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0008252//nucleotidase activity;GO:0016740//transferase activity;GO:0036094//small molecule binding;GO:0008252//nucleotidase activity;GO:0046872//metal ion binding GO:0046128;GO:0006213//pyrimidine nucleoside metabolic process;GO:0006753//nucleoside phosphate metabolic process;GO:0009112;GO:0006753//nucleoside phosphate metabolic process;GO:0046128 gi|356991161|ref|NP_001239303.1|/9.38522e-168/cytosolic 5'-nucleotidase 3A isoform 2 [Mus musculus] 18803 4435 20.87666667 18.13 -0.203512453 Down 0.385309715 Plcg1 "phospholipase C, gamma 1" "K01116|1|0.0|2635|mmu:18803|phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]" GO:0016020//membrane;GO:0031252//cell leading edge;GO:0043234//protein complex;GO:0042995//cell projection;GO:0044444//cytoplasmic part GO:0005167;GO:0004629//phospholipase C activity;GO:0060089;GO:0046872//metal ion binding;GO:0008289//lipid binding GO:0001525//angiogenesis;GO:0010631//epithelial cell migration;GO:0050851//antigen receptor-mediated signaling pathway;GO:0015031//protein transport;GO:0014072//response to isoquinoline alkaloid;GO:0000302//response to reactive oxygen species;GO:0032957//inositol trisphosphate metabolic process;GO:0043009//chordate embryonic development;GO:0009628//response to abiotic stimulus;GO:1901019//regulation of calcium ion transmembrane transporter activity;GO:0010595//positive regulation of endothelial cell migration;GO:0070849//response to epidermal growth factor;GO:0006644//phospholipid metabolic process "gi|41393059|ref|NP_067255.2|/0/1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [Mus musculus]" 64297 4525 8.21 6.866666667 -0.25777229 Down 0.385206288 Gprc5b "G protein-coupled receptor, family C, group 5, member B" K04619|1|0.0|702|mmu:64297|G protein-coupled receptor family C group 5 member B GO:0031224//intrinsic component of membrane;GO:0031988//membrane-bounded vesicle;GO:0031981//nuclear lumen;GO:0031224//intrinsic component of membrane;GO:0031988//membrane-bounded vesicle;GO:0031981//nuclear lumen GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0044708//single-organism behavior;GO:0010975//regulation of neuron projection development;GO:0007166//cell surface receptor signaling pathway;GO:0044708//single-organism behavior;GO:0010975//regulation of neuron projection development gi|307746883|ref|NP_001182703.1|/0/G-protein coupled receptor family C group 5 member B isoform 1 precursor [Mus musculus] 103742 762 37.71333333 42.74 0.180512238 Up 0.385196886 Mien1 migration and invasion enhancer 1 K07401|1|5e-47|189|mmu:103742|selenoprotein W-related protein GO:0009898//cytoplasmic side of plasma membrane;GO:0044444//cytoplasmic part GO:0005488//binding GO:0016477//cell migration;GO:0006915//apoptotic process;GO:0031346//positive regulation of cell projection organization;GO:0019725//cellular homeostasis gi|13384990|ref|NP_079835.1|/3.85568e-46/migration and invasion enhancer 1 [Mus musculus] 69009 1164 7.793333333 9.243333333 0.246172687 Up 0.385159276 Thap7 THAP domain containing 7 K10352|1|2e-19|99.0|fch:102051581|myosin heavy chain GO:0016604//nuclear body;GO:0043232 GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding "GO:0006351//transcription, DNA-templated" gi|28076919|ref|NP_081185.1|/2.86426e-152/THAP domain-containing protein 7 [Mus musculus] 319370 1498 14.13 16.39 0.214054389 Up 0.385149874 Ubald2 UBA-like domain containing 2 - - - - gi|564375465|ref|XP_213532.4|/1.9483e-93/PREDICTED: UBA-like domain-containing protein 2 isoform X2 [Rattus norvegicus] 16514 3021.41 80.13333333 90.11333333 0.169338095 Up 0.385027643 Kcnj11 "potassium inwardly rectifying channel, subfamily J, member 11" K05004|1|0.0|743|mmu:16514|potassium inwardly-rectifying channel subfamily J member 11 GO:0043231//intracellular membrane-bounded organelle;GO:0042383//sarcolemma;GO:0005887//integral component of plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042383//sarcolemma;GO:0005887//integral component of plasma membrane GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0031420;GO:0005242//inward rectifier potassium channel activity;GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0031420;GO:0005242//inward rectifier potassium channel activity GO:0046683//response to organophosphorus;GO:0050796//regulation of insulin secretion;GO:0048545//response to steroid hormone;GO:0071805//potassium ion transmembrane transport;GO:0019318//hexose metabolic process;GO:0006873//cellular ion homeostasis;GO:0003008;GO:0046683//response to organophosphorus;GO:0050796//regulation of insulin secretion;GO:0048545//response to steroid hormone;GO:0071805//potassium ion transmembrane transport;GO:0019318//hexose metabolic process;GO:0006873//cellular ion homeostasis;GO:0003008 gi|6754426|ref|NP_034732.1|/0/ATP-sensitive inward rectifier potassium channel 11 isoform 1 [Mus musculus] 56808 5512 0.846666667 0.403333333 -1.069821449 Down 0.385008838 Cacna2d2 "calcium channel, voltage-dependent, alpha 2/delta subunit 2" K04859|1|0.0|2120|mmu:56808|voltage-dependent calcium channel alpha-2/delta-2 GO:0034704//calcium channel complex;GO:0034704//calcium channel complex;GO:0034704//calcium channel complex;GO:0034704//calcium channel complex;GO:0034704//calcium channel complex GO:0043169//cation binding;GO:0005262//calcium channel activity;GO:0016247//channel regulator activity;GO:0043169//cation binding;GO:0005262//calcium channel activity;GO:0016247//channel regulator activity;GO:0043169//cation binding;GO:0005262//calcium channel activity;GO:0016247//channel regulator activity;GO:0043169//cation binding;GO:0005262//calcium channel activity;GO:0043169//cation binding;GO:0005262//calcium channel activity;GO:0016247//channel regulator activity GO:0048741//skeletal muscle fiber development;GO:0050804//modulation of synaptic transmission;GO:0035264//multicellular organism growth;GO:0035265//organ growth;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0048741//skeletal muscle fiber development;GO:0050804//modulation of synaptic transmission;GO:0035264//multicellular organism growth;GO:0035265//organ growth;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0048741//skeletal muscle fiber development;GO:0050804//modulation of synaptic transmission;GO:0035264//multicellular organism growth;GO:0035265//organ growth;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0048741//skeletal muscle fiber development;GO:0050804//modulation of synaptic transmission;GO:0035264//multicellular organism growth;GO:0035265//organ growth;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0048741//skeletal muscle fiber development;GO:0050804//modulation of synaptic transmission;GO:0035264//multicellular organism growth;GO:0035265//organ growth;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport "gi|148689241|gb|EDL21188.1|/0/calcium channel, voltage-dependent, alpha 2/delta subunit 2, isoform CRA_b, partial [Mus musculus]" 107435 1576 9.976666667 11.72 0.232342792 Up 0.384999436 Hat1 histone aminotransferase 1 K11303|1|0.0|842|mmu:107435|histone acetyltransferase 1 [EC:2.3.1.48] GO:0034399//nuclear periphery "GO:0005488//binding;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0008080//N-acetyltransferase activity" GO:0006473//protein acetylation;GO:0031667//response to nutrient levels;GO:0006342//chromatin silencing;GO:0016570//histone modification gi|28076885|ref|NP_080391.2|/0/histone acetyltransferase type B catalytic subunit [Mus musculus] 208884 2995 25.39 28.86666667 0.185144129 Up 0.384999436 Zdhhc9 "zinc finger, DHHC domain containing 9" K16675|1|0.0|677|mmu:208884|palmitoyltransferase ZDHHC9/14/18 [EC:2.3.1.225] GO:0012505//endomembrane system;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0016740//transferase activity - gi|731274463|ref|XP_010606309.1|/0/PREDICTED: palmitoyltransferase ZDHHC9 isoform X1 [Fukomys damarensis] 14977 2358.85 36.71333333 41.70333333 0.183858595 Up 0.384961826 Slc39a7 "solute carrier family 39 (zinc transporter), member 7" "K14713|1|1e-130|469|mmu:14977|solute carrier family 39 (zinc transporter), member 7" GO:0016020//membrane;GO:0016020//membrane - GO:0030001//metal ion transport;GO:0030001//metal ion transport gi|118150668|ref|NP_001071177.1|/1.05299e-129/zinc transporter SLC39A7 precursor [Mus musculus] 75135 1268.03 6.036666667 7.3 0.274144324 Up 0.384943022 4930526I15Rik RIKEN cDNA 4930526I15 gene K11583|1|3e-13|79.3|mmu:19054|serine/threonine-protein phosphatase 2A regulatory subunit B'' - GO:0046872//metal ion binding;GO:0019888//protein phosphatase regulator activity;GO:0046872//metal ion binding;GO:0019888//protein phosphatase regulator activity;GO:0046872//metal ion binding;GO:0019888//protein phosphatase regulator activity GO:0019222//regulation of metabolic process;GO:0008283//cell proliferation;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0006464//cellular protein modification process;GO:0019222//regulation of metabolic process;GO:0008283//cell proliferation;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0006464//cellular protein modification process;GO:0019222//regulation of metabolic process;GO:0008283//cell proliferation;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0006464//cellular protein modification process "gi|148705235|gb|EDL37182.1|/1.41167e-41/mCG146098, isoform CRA_a, partial [Mus musculus]" 69587 3731 7.333333333 6.07 -0.272772601 Down 0.384943022 Pcgf3 polycomb group ring finger 3 K11488|1|6e-149|531|pon:100455376|polycomb group RING finger protein 3 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|537141832|gb|ERE68185.1|/1.9604e-172/polycomb group RING finger protein 3 [Cricetulus griseus] 12953 4019 16.75 14.49666667 -0.208439887 Down 0.384886607 Cry2 cryptochrome 2 (photolyase-like) K02295|1|0.0|1170|mmu:12953|cryptochrome GO:0043231//intracellular membrane-bounded organelle GO:0038023//signaling receptor activity;GO:0003913//DNA photolyase activity;GO:0036094//small molecule binding;GO:0043566//structure-specific DNA binding;GO:0019899//enzyme binding GO:0006366//transcription from RNA polymerase II promoter;GO:0006290//pyrimidine dimer repair;GO:0010966//regulation of phosphate transport;GO:0006886//intracellular protein transport;GO:0006464//cellular protein modification process;GO:0010923//negative regulation of phosphatase activity;GO:0007623//circadian rhythm gi|27312016|ref|NP_034093.1|/0/cryptochrome-2 [Mus musculus] 18588 795 0.073333333 0.4 2.447458977 Up 0.384792583 Pde6g "phosphodiesterase 6G, cGMP-specific, rod, gamma" "K13759|1|2e-22|90.1|ngi:103730334|retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma" - "GO:0030551//cyclic nucleotide binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0030551//cyclic nucleotide binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity" GO:0006468//protein phosphorylation;GO:0050953//sensory perception of light stimulus;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0050953//sensory perception of light stimulus;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway "gi|149055016|gb|EDM06833.1|/4.22022e-22/rCG33796, isoform CRA_a [Rattus norvegicus]" 260297 921 1.153333333 1.753333333 0.604290762 Up 0.384783181 Prrt1 proline-rich transmembrane protein 1 - - - - gi|13562102|ref|NP_112152.1|/8.75673e-76/proline-rich transmembrane protein 1 [Mus musculus] 13875 3503 14.29 16.53 0.210080808 Up 0.38466095 Erf Ets2 repressor factor K09434|1|0.0|830|mmu:13875|ETS domain-containing transcription factor ERF GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0003677//DNA binding GO:0060706//cell differentiation involved in embryonic placenta development;GO:0016337//single organismal cell-cell adhesion;GO:0007398//ectoderm development;GO:0006366//transcription from RNA polymerase II promoter "gi|31418693|gb|AAH53045.1|/0/Erf protein, partial [Mus musculus]" 100736249 798 0.01 0.246666667 4.624490865 Up 0.384642145 Mira mistral long non-coding RNA - - - - - 22172 1347 0.01 0.246666667 4.624490865 Up 0.384642145 Tyms-ps "thymidylate synthase, pseudogene" K00560|1|4e-105|237|cge:100754276|thymidylate synthase [EC:2.1.1.45] GO:0031981//nuclear lumen;GO:0019866//organelle inner membrane;GO:0044429 "GO:0042802//identical protein binding;GO:0042083//5,10-methylenetetrahydrofolate-dependent methyltransferase activity;GO:0003723//RNA binding;GO:0019842//vitamin binding" GO:0006213//pyrimidine nucleoside metabolic process;GO:0048017//inositol lipid-mediated signaling;GO:0000082//G1/S transition of mitotic cell cycle;GO:0001501//skeletal system development;GO:0009177;GO:0031960//response to corticosteroid;GO:0006259//DNA metabolic process;GO:0040007//growth;GO:0006760//folic acid-containing compound metabolic process;GO:0002069;GO:0005975//carbohydrate metabolic process;GO:0009212//pyrimidine deoxyribonucleoside triphosphate biosynthetic process;GO:0048511//rhythmic process;GO:0019087//transformation of host cell by virus;GO:0006206//pyrimidine nucleobase metabolic process;GO:0033273//response to vitamin;GO:0097305//response to alcohol;GO:0009887//organ morphogenesis gi|537221838|gb|ERE82569.1|/3.44769e-104/thymidylate synthase-like protein [Cricetulus griseus] 20262 1136 0.01 0.246666667 4.624490865 Up 0.384642145 Stmn3 stathmin-like 3 K04381|1|4e-39|164|cmy:102930305|stathmin GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0008092//cytoskeletal protein binding GO:0031109//microtubule polymerization or depolymerization;GO:0030030//cell projection organization;GO:0016601//Rac protein signal transduction "gi|149033946|gb|EDL88729.1|/3.13558e-79/stathmin-like 3, isoform CRA_b [Rattus norvegicus]" 14385 2109.14 8.46 10.01666667 0.243672922 Up 0.384585731 Slc37a4 "solute carrier family 37 (glucose-6-phosphate transporter), member 4" "K08171|1|0.0|739|mmu:14385|MFS transporter, OPA family, solute carrier family 37 (glycerol-6-phosphate transporter), member 4" GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0015119;GO:0015119;GO:0015119 GO:0033500//carbohydrate homeostasis;GO:0006639//acylglycerol metabolic process;GO:0001818//negative regulation of cytokine production;GO:0006073//cellular glucan metabolic process;GO:0009791//post-embryonic development;GO:0015712//hexose phosphate transport;GO:0008645//hexose transport;GO:0019318//hexose metabolic process;GO:0044093;GO:0032787//monocarboxylic acid metabolic process;GO:0009746;GO:0002244//hematopoietic progenitor cell differentiation;GO:0030595//leukocyte chemotaxis;GO:0055092//sterol homeostasis;GO:0031667//response to nutrient levels;GO:0006875//cellular metal ion homeostasis;GO:0001776//leukocyte homeostasis;GO:0033500//carbohydrate homeostasis;GO:0006639//acylglycerol metabolic process;GO:0001818//negative regulation of cytokine production;GO:0006073//cellular glucan metabolic process;GO:0009791//post-embryonic development;GO:0015712//hexose phosphate transport;GO:0008645//hexose transport;GO:0019318//hexose metabolic process;GO:0044093;GO:0032787//monocarboxylic acid metabolic process;GO:0009746;GO:0002244//hematopoietic progenitor cell differentiation;GO:0030595//leukocyte chemotaxis;GO:0055092//sterol homeostasis;GO:0031667//response to nutrient levels;GO:0006875//cellular metal ion homeostasis;GO:0001776//leukocyte homeostasis;GO:0033500//carbohydrate homeostasis;GO:0006639//acylglycerol metabolic process;GO:0001818//negative regulation of cytokine production;GO:0006073//cellular glucan metabolic process;GO:0009791//post-embryonic development;GO:0015712//hexose phosphate transport;GO:0008645//hexose transport;GO:0019318//hexose metabolic process;GO:0044093;GO:0032787//monocarboxylic acid metabolic process;GO:0009746;GO:0002244//hematopoietic progenitor cell differentiation;GO:0030595//leukocyte chemotaxis;GO:0055092//sterol homeostasis;GO:0031667//response to nutrient levels;GO:0006875//cellular metal ion homeostasis;GO:0001776//leukocyte homeostasis gi|51592076|ref|NP_032089.2|/0/glucose-6-phosphate translocase [Mus musculus] 17130 2971 8.796666667 10.35333333 0.235066479 Up 0.384585731 Smad6 SMAD family member 6 K04677|1|0.0|803|mmu:17130|mothers against decapentaplegic homolog 6 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0070697//activin receptor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005160//transforming growth factor beta receptor binding;GO:0000975//regulatory region DNA binding;GO:0043169//cation binding;GO:0046332//SMAD binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0005072//transforming growth factor beta receptor, cytoplasmic mediator activity" GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006915//apoptotic process;GO:0019229//regulation of vasoconstriction;GO:0034405//response to fluid shear stress;GO:0000084//mitotic S phase;GO:0042311//vasodilation;GO:0001933//negative regulation of protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0002376//immune system process;GO:0000578//embryonic axis specification;GO:0055006//cardiac cell development;GO:0007155//cell adhesion;GO:0048514//blood vessel morphogenesis;GO:0007183//SMAD protein complex assembly gi|254675285|ref|NP_032568.3|/0/mothers against decapentaplegic homolog 6 [Mus musculus] 75736 1090 7.736666667 9.18 0.246782037 Up 0.384566926 Bcl2l12 BCL2-like 12 (proline rich) - - - GO:0006915//apoptotic process gi|21553305|ref|NP_083686.1|/2.54213e-99/bcl-2-like protein 12 [Mus musculus] 20818 2991 17.84666667 20.54333333 0.203015652 Up 0.384538719 Srprb "signal recognition particle receptor, B subunit" K12272|1|8e-135|484|mmu:20818|signal recognition particle receptor subunit beta;K14736|3|5e-126|454|ngi:103748952|transferrin "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0016323//basolateral plasma membrane;GO:0005874//microtubule;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0005768//endosome;GO:0012505//endomembrane system" GO:0032550;GO:0044389//ubiquitin-like protein ligase binding GO:0010467//gene expression;GO:0006613//cotranslational protein targeting to membrane;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0035556//intracellular signal transduction;GO:0019538//protein metabolic process gi|6678137|ref|NP_033301.1|/7.01645e-134/signal recognition particle receptor subunit beta [Mus musculus] 27008 6708 21.18666667 18.48666667 -0.196671508 Down 0.384538719 Micall1 "microtubule associated monooxygenase, calponin and LIM domain containing -like 1" K19948|1|0.0|1332|mmu:27008|MICAL-like protein - - - - 14164 3909 76.00333333 85.41333333 0.168398604 Up 0.384407086 Fgf1 fibroblast growth factor 1 K18496|1|2e-86|323|rno:25317|fibroblast growth factor 1 GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0044421;GO:0031012//extracellular matrix GO:0005539//glycosaminoglycan binding;GO:0070851//growth factor receptor binding;GO:0031072//heat shock protein binding GO:0001932//regulation of protein phosphorylation;GO:0008284//positive regulation of cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001823//mesonephros development;GO:0016477//cell migration;GO:0003156//regulation of organ formation;GO:0009408//response to heat;GO:0006695//cholesterol biosynthetic process;GO:0001570//vasculogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001525//angiogenesis;GO:0030323//respiratory tube development;GO:0014855 "gi|148678123|gb|EDL10070.1|/3.85261e-119/fibroblast growth factor 1, isoform CRA_c, partial [Mus musculus]" 20751 1226 72.92666667 82.26333333 0.173803079 Up 0.384275452 Spr sepiapterin reductase K00072|1|2e-144|514|mmu:20751|sepiapterin reductase [EC:1.1.1.153] - - - - 74249 3657 82.49 73.14666667 -0.173427115 Down 0.384275452 Lrrc2 leucine rich repeat containing 2 K12796|1|6e-21|106|ola:101172095|erbb2-interacting protein - - - gi|146219826|ref|NP_083114.2|/0/leucine-rich repeat-containing protein 2 [Mus musculus] 100526465 91 0.933333333 1.496666667 0.681288618 Up 0.384275452 Mir3057 microRNA 3057 - - - - - 71389 10375 6.753333333 5.563333333 -0.279650219 Down 0.384209636 Chd6 chromodomain helicase DNA binding protein 6 K14436|1|0.0|2464|mmu:71389|chromodomain-helicase-DNA-binding protein 6 [EC:3.6.4.12] - - - gi|61742812|ref|NP_775544.2|/0/chromodomain-helicase-DNA-binding protein 6 [Mus musculus] 51813 1920.12 4.68 3.713333333 -0.333793703 Down 0.384172026 Ccnc cyclin C K15161|1|5e-154|548|umr:103675873|cyclin C GO:0043234//protein complex;GO:0044451;GO:0043234//protein complex;GO:0044451;GO:0043234//protein complex;GO:0044451;GO:0043234//protein complex;GO:0044451 GO:0019900//kinase binding;GO:0019900//kinase binding;GO:0019900//kinase binding;GO:0019900//kinase binding "GO:0051726//regulation of cell cycle;GO:0006351//transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:0006351//transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:0006351//transcription, DNA-templated;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0051726//regulation of cell cycle" "gi|148673613|gb|EDL05560.1|/0/cyclin C, isoform CRA_d, partial [Mus musculus]" 100503890 1202 11.58333333 13.50666667 0.221621196 Up 0.384143819 Pet100 PET100 homolog "K18186|1|5e-32|140|mmu:100503890|protein PET100, animal type" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - "gi|305410813|ref|NP_001182173.1|/4.5115e-31/protein PET100 homolog, mitochondrial [Mus musculus]" 65972 997 14.33333333 16.55 0.207457058 Up 0.384143819 Ifi30 interferon gamma inducible protein 30 "K08059|1|3e-124|447|mmu:65972|interferon, gamma-inducible protein 30" GO:0000323//lytic vacuole;GO:0016020//membrane "GO:0016667//oxidoreductase activity, acting on a sulfur group of donors" GO:0002478;GO:0008285//negative regulation of cell proliferation;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0044710;GO:0031647//regulation of protein stability gi|9837556|gb|AAG00598.1|AF290973_1/2.33398e-125/lysosomal thiol reductase IP30 precursor [Mus musculus] 15024 2892.58 2.513333333 3.313333333 0.398681328 Up 0.383946369 H2-T10 "histocompatibility 2, T region locus 10" "K06751|1|0.0|447|mmu:15024|major histocompatibility complex, class I" - - GO:0043583//ear development;GO:0043583//ear development gi|199664|gb|AAA39695.1|/0/MHC H2-TL-T10-129 [Mus musculus] 270110 4530 14.17333333 16.37666667 0.208462642 Up 0.383664297 Irf2bp2 interferon regulatory factor 2 binding protein 2 K11318|1|0.0|677|ocu:103350931|ataxin-7;K04498|2|2e-52|211|chx:102187824|E1A/CREB-binding protein [EC:2.3.1.48];K11412|3|5e-23|113|aam:106491452|NAD-dependent deacetylase sirtuin 2 [EC:3.5.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity "GO:0006351//transcription, DNA-templated" gi|257196179|ref|NP_001158070.1|/0/interferon regulatory factor 2-binding protein 2 [Mus musculus] 667370 2013 3.54 4.47 0.336525471 Up 0.383560871 Ifit3b interferon-induced protein with tetratricopeptide repeats 3B K14217|1|3e-83|311|cfa:488947|interferon-induced protein with tetratricopeptide repeats 1 GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding GO:0035456//response to interferon-beta;GO:0006952//defense response;GO:0008283//cell proliferation;GO:0002252;GO:0035455//response to interferon-alpha;GO:0051707//response to other organism;GO:0006915//apoptotic process gi|74151869|dbj|BAE29721.1|/0/unnamed protein product [Mus musculus] 14593 2387 4.313333333 5.35 0.31073568 Up 0.383485652 Ggps1 geranylgeranyl diphosphate synthase 1 "K00804|1|1e-171|606|mmu:14593|geranylgeranyl diphosphate synthase, type III [EC:2.5.1.1 2.5.1.10 2.5.1.29]" GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0004659//prenyltransferase activity GO:0006720//isoprenoid metabolic process;GO:0008654//phospholipid biosynthetic process;GO:0008203//cholesterol metabolic process gi|6806915|ref|NP_034412.1|/9.356e-171/geranylgeranyl pyrophosphate synthase [Mus musculus] 268319 1906 0.543333333 1.026666667 0.918058386 Up 0.38347625 BC025920 zinc finger protein pseudogene K09228|1|4e-46|163|ngi:103737238|KRAB domain-containing zinc finger protein GO:0005634//nucleus - - gi|148699443|gb|EDL31390.1|/1.57511e-69/mCG148085 [Mus musculus] 68559 1229 72.53333333 81.36666667 0.165793739 Up 0.38347625 Pdrg1 p53 and DNA damage regulated 1 - GO:0044424;GO:0043234//protein complex GO:0005515//protein binding GO:0044267//cellular protein metabolic process gi|32490570|ref|NP_849270.1|/3.00609e-54/p53 and DNA damage-regulated protein 1 [Mus musculus] 231507 696 0.583333333 1.076666667 0.884179243 Up 0.38343864 Plac8 placenta-specific 8 K07188|1|3e-12|73.9|amj:102571969|hormone-sensitive lipase [EC:3.1.1.79] GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0006952//defense response;GO:0006915//apoptotic process;GO:0035264//multicellular organism growth;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation gi|21105853|ref|NP_631937.1|/7.58618e-64/placenta-specific gene 8 protein [Mus musculus] 71746 2550 7.473333333 8.896666667 0.251513027 Up 0.383410433 Rgl3 ral guanine nucleotide dissociation stimulator-like 3 K17639|1|0.0|1083|mmu:71746|ral guanine nucleotide dissociation stimulator-like 3 - - - - 93715 4660 2.22 2.98 0.424752654 Up 0.383410433 Pcdhga7 "protocadherin gamma subfamily A, 7" K16495|1|0.0|1738|mmu:93715|protocadherin gamma subfamily A GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|50878294|ref|NP_291068.2|/0/protocadherin gamma-A7 precursor [Mus musculus] 240514 4401 7.496666667 8.916666667 0.25025523 Up 0.383410433 Ccdc85b coiled-coil domain containing 85B K16758|1|3e-52|210|pale:102884578|coiled-coil domain-containing protein 85B GO:0043229//intracellular organelle;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding "GO:0044763;GO:0006351//transcription, DNA-templated;GO:0016049//cell growth;GO:0006351//transcription, DNA-templated" gi|149062067|gb|EDM12490.1|/1.3496e-32/similar to Delta-interacting protein A (Hepatitis delta antigen interacting protein A) (predicted) [Rattus norvegicus] 69308 823 0.486666667 0.126666667 -1.941897045 Down 0.383325811 1700007P06Rik RIKEN cDNA 1700007P06 gene - - - - - 16775 6046 11.59666667 9.9 -0.228209748 Down 0.383269397 Lama4 "laminin, alpha 4" "K06241|1|0.0|3647|mmu:16775|laminin, alpha 4" GO:0031988//membrane-bounded vesicle;GO:0043256//laminin complex GO:0005515//protein binding;GO:0005198//structural molecule activity GO:0009790//embryo development;GO:0016477//cell migration;GO:0007155//cell adhesion;GO:0045444//fat cell differentiation gi|148747408|ref|NP_034811.2|/0/laminin subunit alpha-4 precursor [Mus musculus] 22393 3564 68.56333333 77.22 0.171537304 Up 0.383222385 Wfs1 Wolfram syndrome 1 homolog (human) K14020|1|0.0|1595|mmu:22393|wolfamin GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0044389//ubiquitin-like protein ligase binding;GO:0008134//transcription factor binding GO:0006984//ER-nucleus signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006874//cellular calcium ion homeostasis;GO:0043066//negative regulation of apoptotic process;GO:0040007//growth;GO:0031647//regulation of protein stability;GO:0033500//carbohydrate homeostasis;GO:0006816//calcium ion transport;GO:0003014//renal system process;GO:0050953//sensory perception of light stimulus;GO:0010604;GO:0007635//chemosensory behavior;GO:0050954//sensory perception of mechanical stimulus;GO:0044092//negative regulation of molecular function;GO:0016567//protein ubiquitination;GO:0033554//cellular response to stress;GO:0070843//misfolded protein transport;GO:0007049//cell cycle gi|6755997|ref|NP_035846.1|/0/wolframin [Mus musculus] 13803 4752 3.303333333 4.2 0.346466771 Up 0.383212983 Enc1 ectodermal-neural cortex 1 K10462|1|0.0|1164|mmu:13803|kelch-like protein 25/37 (ectoderm-neural cortex protein) GO:0031461//cullin-RING ubiquitin ligase complex;GO:0043232;GO:0034399//nuclear periphery GO:0008092//cytoskeletal protein binding GO:0006412//translation;GO:0048731//system development;GO:0010498//proteasomal protein catabolic process;GO:0032446//protein modification by small protein conjugation gi|826351127|ref|XP_012520060.1|/0/PREDICTED: ectoderm-neural cortex protein 1 isoform X1 [Propithecus coquereli] 56374 1562 66.86 75.44333333 0.174250065 Up 0.383081349 Tmem59 transmembrane protein 59 - GO:0012505//endomembrane system;GO:0005770//late endosome;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane "GO:0005488//binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0006914//autophagy gi|227330571|ref|NP_083841.4|/1.95305e-160/transmembrane protein 59 precursor [Mus musculus] 84682 727 17.30666667 19.93 0.203613828 Up 0.383071947 Cox4i2 cytochrome c oxidase subunit IV isoform 2 K02263|1|2e-90|333|mmu:84682|cytochrome c oxidase subunit 4 GO:0005746//mitochondrial respiratory chain GO:0015002//heme-copper terminal oxidase activity GO:0044710 "gi|148674042|gb|EDL05989.1|/1.49903e-89/cytochrome c oxidase subunit IV isoform 2, isoform CRA_b, partial [Mus musculus]" 236573 3633 2.96 3.813333333 0.36545547 Up 0.38280868 Gbp9 guanylate-binding protein 9 K17339|1|2e-16|90.9|hro:HELRODRAFT_73066|atlastin [EC:3.6.5.-] GO:0031982//vesicle;GO:0020003//symbiont-containing vacuole - GO:0001562//response to protozoan;GO:0042742//defense response to bacterium;GO:0034341//response to interferon-gamma;GO:0032496//response to lipopolysaccharide;GO:0035456//response to interferon-beta;GO:0051702//interaction with symbiont "gi|27370144|ref|NP_766365.1|/0/guanylate binding protein family, member 9 [Mus musculus]" 66102 2448 4.67 5.743333333 0.298465746 Up 0.382686449 Cxcl16 chemokine (C-X-C motif) ligand 16 K10035|1|1e-127|460|mmu:66102|C-X-C motif chemokine 16 GO:0031224//intrinsic component of membrane;GO:0044421 GO:0005125//cytokine activity;GO:0030228//lipoprotein particle receptor activity GO:0016049//cell growth;GO:0034097//response to cytokine;GO:0006897//endocytosis;GO:0030595//leukocyte chemotaxis gi|83745124|ref|NP_075647.3|/8.56225e-127/C-X-C motif chemokine 16 precursor [Mus musculus] 22327 1601 7.593333333 9.003333333 0.245725893 Up 0.382686449 Vbp1 von Hippel-Lindau binding protein 1 K20044|1|9e-84|313|gfr:102040199|phosphatidylinositol-binding clathrin assembly protein - - - - 103554 6454 39.24333333 34.66 -0.179175935 Down 0.382677047 Psme4 "proteasome (prosome, macropain) activator subunit 4" K06699|1|0.0|3494|mmu:103554|proteasome activator subunit 4 GO:0016604//nuclear body;GO:0043234//protein complex;GO:0044444//cytoplasmic part - "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0006915//apoptotic process;GO:0044764;GO:0051320;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|117956381|ref|NP_598774.2|/0/proteasome activator complex subunit 4 [Mus musculus] 100503337 664 0.55 1.033333333 0.909802191 Up 0.382667645 Gm9895 predicted gene 9895 K03767|1|1e-07|58.5|cge:103159182|peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8];K08462|2|4e-07|57.0|lve:103079827|G protein-coupled receptor 125 - - - gi|26389220|dbj|BAC25699.1|/7.75056e-76/unnamed protein product [Mus musculus] 18220 2639 68.44333333 76.8 0.166196287 Up 0.382658242 Nucb1 nucleobindin 1 K20371|1|0.0|686|mmu:18220|nucleobindin GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0046872//metal ion binding - "gi|148690913|gb|EDL22860.1|/0/nucleobindin 1, isoform CRA_a, partial [Mus musculus]" 18582 1109 34.8 39.37 0.178009406 Up 0.382592425 Pde6d "phosphodiesterase 6D, cGMP-specific, rod, delta" "K13758|1|4e-94|347|fca:101096755|retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta" - "GO:0005488//binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004857//enzyme inhibitor activity" GO:0044092//negative regulation of molecular function;GO:0050953//sensory perception of light stimulus;GO:0007165//signal transduction "gi|755761636|ref|XP_003991301.3|/3.66913e-93/PREDICTED: retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [Felis catus]" 233876 2511 2.39 3.173333333 0.408988455 Up 0.382423183 Hirip3 HIRA interacting protein 3 - GO:0043231//intracellular membrane-bounded organelle - - gi|27370102|ref|NP_766334.1|/0/HIRA-interacting protein 3 [Mus musculus] 18845 11049 6.64 5.47 -0.279642409 Down 0.382376171 Plxna2 plexin A2 K06820|1|0.0|3617|mmu:18845|plexin A - - - "gi|148680991|gb|EDL12938.1|/0/plexin A2, isoform CRA_b, partial [Mus musculus]" 68481 2342.43 8.313333333 9.83 0.241764357 Up 0.382300952 Mpzl1 myelin protein zero-like 1 K06770|1|4e-127|458|mmu:68481|myelin protein zero GO:0031224//intrinsic component of membrane;GO:0016021//integral component of membrane GO:0005488//binding GO:0007167//enzyme linked receptor protein signaling pathway gi|49457857|ref|NP_001001880.1|/1.33455e-86/myelin protein zero-like protein 1 isoform b precursor [Mus musculus] 66181 738 63.57666667 71.74333333 0.174347399 Up 0.382291549 Nop10 NOP10 ribonucleoprotein K11130|1|4e-31|137|rno:691534|H/ACA ribonucleoprotein complex subunit 3 - - - - 66168 1693 62.90333333 70.96333333 0.173937309 Up 0.382084697 Grina "glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)" K06890|1|6e-119|420|cjc:100394086|uncharacterized protein - - - - 102747 2756.42 1.87 2.57 0.458730089 Up 0.382047087 Lrrc49 leucine rich repeat containing 49 K16606|1|0.0|1346|cge:100752897|leucine-rich repeat-containing protein 49 GO:0015630//microtubule cytoskeleton - - gi|225690572|ref|NP_001139519.1|/0/leucine-rich repeat-containing protein 49 isoform 3 [Mus musculus] 107250 1383 1.87 2.57 0.458730089 Up 0.382047087 Kazald1 Kazal-type serine peptidase inhibitor domain 1 K08784|1|5e-19|98.2|lcm:102361645|HtrA serine peptidase 1 [EC:3.4.21.-] GO:0005578//proteinaceous extracellular matrix GO:0019838//growth factor binding GO:0043062//extracellular structure organization;GO:0016049//cell growth;GO:0048869//cellular developmental process gi|164698466|ref|NP_849260.2|/1.10325e-164/kazal-type serine protease inhibitor domain-containing protein 1 precursor [Mus musculus] 74493 6503 8.7 7.296666667 -0.253777852 Down 0.382037685 Tnks2 "tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2" K10799|1|0.0|2143|mmu:74493|tankyrase [EC:2.4.2.30] "GO:0000781//chromosome, telomeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0005813//centrosome;GO:0012505//endomembrane system;GO:0044444//cytoplasmic part" "GO:0005515//protein binding;GO:0043169//cation binding;GO:0016763//transferase activity, transferring pentosyl groups" GO:0034502//protein localization to chromosome;GO:0016567//protein ubiquitination;GO:0007004//telomere maintenance via telomerase;GO:0035264//multicellular organism growth;GO:0030177//positive regulation of Wnt signaling pathway;GO:0006471//protein ADP-ribosylation gi|254750660|ref|NP_001157107.1|/0/tankyrase-2 [Mus musculus] 103743 1444 7.433333333 8.83 0.248404134 Up 0.382037685 Tmem98 transmembrane protein 98 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - "gi|148683700|gb|EDL15647.1|/1.18721e-124/transmembrane protein 98, isoform CRA_a, partial [Mus musculus]" 67405 1237 0.443333333 0.886666667 1 Up 0.38198127 Nts neurotensin K05235|1|6e-93|343|mmu:67405|neurotensin "GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0005179//hormone activity GO:0003018;GO:0007154//cell communication gi|13277358|ref|NP_077755.1|/4.77977e-92/neurotensin/neuromedin N precursor [Mus musculus] 269614 2600.78 26.67 23.44666667 -0.185834991 Down 0.381830832 Pank4 pantothenate kinase 4 K09680|1|0.0|1159|mmu:269614|type II pantothenate kinase [EC:2.7.1.33] GO:0044424;GO:0044424 GO:0032550;GO:0032550 GO:0009108//coenzyme biosynthetic process;GO:0009108//coenzyme biosynthetic process gi|240255614|ref|NP_766578.2|/0/pantothenate kinase 4 isoform 2 [Mus musculus] 104718 3458 37.32333333 32.87666667 -0.183013806 Down 0.381793223 Ttc7b tetratricopeptide repeat domain 7B K09667|1|5e-06|56.6|aqu:100633595|protein O-GlcNAc transferase [EC:2.4.1.255] - - - "gi|148686951|gb|EDL18898.1|/0/mCG145297, partial [Mus musculus]" 80283 1896 13.77 15.90666667 0.208102983 Up 0.381765016 Abtb1 ankyrin repeat and BTB (POZ) domain containing 1 K10520|1|0.0|927|mmu:80283|ankyrin repeat and BTB/POZ domain-containing protein 1 GO:0016020//membrane;GO:0031981//nuclear lumen "GO:0008135//translation factor activity, RNA binding" GO:0006412//translation gi|537136864|gb|ERE66765.1|/0/podocalyxin-like protein 2 [Cricetulus griseus] 230596 1519 8.393333333 9.9 0.238184648 Up 0.381765016 Prpf38a PRP38 pre-mRNA processing factor 38 (yeast) domain containing A K12849|1|2e-110|401|mmu:230596|pre-mRNA-splicing factor 38A GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex - GO:0006396//RNA processing gi|676264542|gb|KFO20929.1|/1.65082e-111/Pre-mRNA-splicing factor 38A [Fukomys damarensis] 13637 2153 0.6 1.09 0.861293729 Up 0.381727406 Efna2 ephrin A2 K05462|1|2e-115|419|rno:84358|ephrin-A GO:0031224//intrinsic component of membrane;GO:0045202//synapse;GO:0043025//neuronal cell body GO:0005102//receptor binding GO:0042471//ear morphogenesis;GO:0048771//tissue remodeling;GO:0002573//myeloid leukocyte differentiation;GO:0021988//olfactory lobe development;GO:0006935//chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|247269362|ref|NP_031935.3|/1.432e-114/ephrin-A2 precursor [Mus musculus] 67054 2394 61.88666667 69.70333333 0.171599032 Up 0.381689797 Paics "phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase" K01587|1|0.0|865|mmu:67054|phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6] - GO:0032550;GO:0016866//intramolecular transferase activity;GO:0016881//acid-amino acid ligase activity;GO:0005515//protein binding;GO:0016831//carboxy-lyase activity GO:0006188//IMP biosynthetic process gi|13385434|ref|NP_080215.1|/0/multifunctional protein ADE2 [Mus musculus] 13088 1878 5.68 4.62 -0.297998078 Down 0.381661589 Cyp2b10 "cytochrome P450, family 2, subfamily b, polypeptide 10" "K07412|1|0.0|907|mmu:13088|cytochrome P450, family 2, subfamily B [EC:1.14.14.1]" GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0006629//lipid metabolic process;GO:0010038//response to metal ion;GO:0043434//response to peptide hormone;GO:0042493//response to drug;GO:0044237//cellular metabolic process gi|50080153|ref|NP_034129.1|/0/cytochrome P450 2B10 precursor [Mus musculus] 100504346 867 7.126666667 5.903333333 -0.271697641 Down 0.381614577 Gm13304 predicted gene 13304 K16062|1|9e-57|222|mmu:100862177|C-C motif chemokine 21 GO:0009986//cell surface GO:0005125//cytokine activity GO:0001952//regulation of cell-matrix adhesion;GO:0033627//cell adhesion mediated by integrin;GO:0031346//positive regulation of cell projection organization;GO:0043410//positive regulation of MAPK cascade;GO:0034694//response to prostaglandin;GO:0002408//myeloid dendritic cell chemotaxis;GO:0001934//positive regulation of protein phosphorylation;GO:0007254//JNK cascade;GO:0031269//pseudopodium assembly;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0001767;GO:0051283//negative regulation of sequestering of calcium ion;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0030041//actin filament polymerization;GO:0043066//negative regulation of apoptotic process;GO:0050927//positive regulation of positive chemotaxis gi|3169697|gb|AAC17929.1|/6.93617e-56/beta chemokine Exodus-2 [Mus musculus] 100504239 867 7.126666667 5.903333333 -0.271697641 Down 0.381614577 Gm10591 predicted gene 10591 K16062|1|9e-57|222|mmu:100862177|C-C motif chemokine 21 GO:0009986//cell surface GO:0005125//cytokine activity GO:0001952//regulation of cell-matrix adhesion;GO:0033627//cell adhesion mediated by integrin;GO:0031346//positive regulation of cell projection organization;GO:0043410//positive regulation of MAPK cascade;GO:0034694//response to prostaglandin;GO:0002408//myeloid dendritic cell chemotaxis;GO:0001934//positive regulation of protein phosphorylation;GO:0007254//JNK cascade;GO:0031269//pseudopodium assembly;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0001767;GO:0051283//negative regulation of sequestering of calcium ion;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0030041//actin filament polymerization;GO:0043066//negative regulation of apoptotic process;GO:0050927//positive regulation of positive chemotaxis gi|3169697|gb|AAC17929.1|/6.93617e-56/beta chemokine Exodus-2 [Mus musculus] 22193 1562 22.26 25.46333333 0.193967698 Up 0.381492346 Ube2e3 ubiquitin-conjugating enzyme E2E 3 K20217|1|8e-87|323|gja:107117950|ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23] - - - gi|109692276|gb|ABG37966.1|/7.21466e-104/unknown [Rattus norvegicus] 353190 3343 3.05 3.913333333 0.35958876 Up 0.381435932 Edc3 enhancer of mRNA decapping 3 K12615|1|0.0|970|mmu:353190|enhancer of mRNA-decapping protein 3 - - - - 73490 1454 1.16 1.746666667 0.590479506 Up 0.381407725 Mipol1 mirror-image polydactyly 1 K15201|1|2e-07|59.7|ssc:100154260|general transcription factor 3C polypeptide 3 (transcription factor C subunit 4);K16464|2|5e-07|58.5|aam:106499931|centrosomal protein CEP250;K19922|5|6e-07|58.2|acs:103280124|peripheral-type benzodiazepine receptor-associated protein 1 - - - gi|148704756|gb|EDL36703.1|/0/mCG1040730 [Mus musculus] 19253 1587 1.156666667 1.743333333 0.591875284 Up 0.381407725 Ptpn18 "protein tyrosine phosphatase, non-receptor type 18" K18024|1|0.0|926|mmu:19253|tyrosine-protein phosphatase non-receptor type 12/18/22 [EC:3.1.3.48] GO:0043231//intracellular membrane-bounded organelle GO:0004725//protein tyrosine phosphatase activity;GO:0005488//binding GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|113199761|ref|NP_035336.2|/0/tyrosine-protein phosphatase non-receptor type 18 [Mus musculus] 30935 3268 5.446666667 6.606666667 0.278548979 Up 0.381407725 Tor3a "torsin family 3, member A" - GO:0044432 GO:0016836//hydro-lyase activity;GO:0032550 GO:0051084//'de novo' posttranslational protein folding gi|74212660|dbj|BAE31066.1|/0/unnamed protein product [Mus musculus] 67781 1973 16.81333333 19.34333333 0.202230653 Up 0.381370115 Ilf2 interleukin enhancer binding factor 2 K13089|1|0.0|642|ecb:100056483|interleukin enhancer-binding factor 2 GO:0032991//macromolecular complex;GO:0031981//nuclear lumen GO:0032550;GO:0003723//RNA binding;GO:0003824//catalytic activity "GO:0002376//immune system process;GO:0006351//transcription, DNA-templated" gi|149751298|ref|XP_001495089.1|/0/PREDICTED: interleukin enhancer-binding factor 2 [Equus caballus] 105446 1560 7.476666667 8.863333333 0.245454157 Up 0.381370115 Gmpr2 guanosine monophosphate reductase 2 K00364|1|0.0|698|mmu:105446|GMP reductase [EC:1.7.1.7] GO:0044444//cytoplasmic part "GO:0043169//cation binding;GO:0016657//oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor" GO:0006753//nucleoside phosphate metabolic process;GO:0009112;GO:0034654 gi|29568082|ref|NP_818773.1|/0/GMP reductase 2 [Mus musculus] 66147 1909 10.96 12.8 0.223896012 Up 0.381294896 Necap2 NECAP endocytosis associated 2 K20069|1|8e-130|466|mmu:66147|adaptin ear-binding coat-associated protein 1/2 GO:0012505//endomembrane system;GO:0031982//vesicle;GO:0030118//clathrin coat - GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport gi|13384758|ref|NP_079659.1|/6.72232e-129/adaptin ear-binding coat-associated protein 2 [Mus musculus] 50706 3155.43 13 11.16 -0.220174596 Down 0.381294896 Postn "periostin, osteoblast specific factor" K19519|1|3e-166|588|lcm:102362551|transforming growth factor-beta-induced protein GO:0031012//extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0031012//extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0031012//extracellular matrix;GO:0043231//intracellular membrane-bounded organelle GO:0005539//glycosaminoglycan binding;GO:0005539//glycosaminoglycan binding;GO:0005539//glycosaminoglycan binding GO:0043062//extracellular structure organization;GO:0048856//anatomical structure development;GO:0007219//Notch signaling pathway;GO:0022610;GO:0043062//extracellular structure organization;GO:0048856//anatomical structure development;GO:0007219//Notch signaling pathway;GO:0022610;GO:0043062//extracellular structure organization;GO:0048856//anatomical structure development;GO:0007219//Notch signaling pathway;GO:0022610 gi|7657429|ref|NP_056599.1|/0/periostin isoform 1 precursor [Mus musculus] 26426 1448 11.37333333 13.21666667 0.216703219 Up 0.381294896 Nubp2 nucleotide binding protein 2 K03593|1|5e-44|181|hmg:100198387|ATP-binding protein involved in chromosome partitioning GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0032550 - gi|6754908|ref|NP_036086.1|/1.10752e-154/cytosolic Fe-S cluster assembly factor NUBP2 [Mus musculus] 13033 1979 846.8466667 945.2133333 0.158539207 Up 0.381219677 Ctsd cathepsin D K01379|1|0.0|777|mmu:13033|cathepsin D [EC:3.4.23.5] GO:0000323//lytic vacuole;GO:0048770;GO:0044421 GO:0004175//endopeptidase activity;GO:0033218//amide binding GO:0044248;GO:0048754//branching morphogenesis of an epithelial tube;GO:0019538//protein metabolic process;GO:0007033//vacuole organization gi|74198040|dbj|BAE35200.1|/0/unnamed protein product [Mus musculus] 66043 931 864.31 962.7466667 0.15560737 Up 0.381219677 Atp5d "ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit" K02134|1|6e-64|246|mmu:66043|F-type H+-transporting ATPase subunit delta "GO:0033178//proton-transporting two-sector ATPase complex, catalytic domain;GO:0005743//mitochondrial inner membrane" GO:0005515//protein binding;GO:0019829//cation-transporting ATPase activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0009154//purine ribonucleotide catabolic process;GO:0006811//ion transport "gi|148699644|gb|EDL31591.1|/1.30267e-85/ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit, isoform CRA_b, partial [Mus musculus]" 223499 1543 9.38 11.03333333 0.234208888 Up 0.381125653 Dcaf13 DDB1 and CUL4 associated factor 13 K11806|1|0.0|913|mmu:223499|WD repeat and SOF domain-containing protein 1 - - - "gi|148676836|gb|EDL08783.1|/0/WD repeats and SOF domain containing 1, isoform CRA_b, partial [Mus musculus]" 70551 3390 1.883333333 1.273333333 -0.564678229 Down 0.381097446 Tmtc4 transmembrane and tetratricopeptide repeat containing 4 K09667|1|2e-21|107|ola:101164571|protein O-GlcNAc transferase [EC:2.4.1.255] GO:0031224//intrinsic component of membrane - - "gi|148668309|gb|EDL00639.1|/0/transmembrane and tetratricopeptide repeat containing 4, isoform CRA_c, partial [Mus musculus]" 66449 552 60.47333333 68.02666667 0.169801295 Up 0.381078642 Pam16 presequence translocase-asssociated motor 16 homolog (S. cerevisiae) K17805|1|1e-43|177|tup:102475440|mitochondrial import inner membrane translocase subunit TIM16 GO:0005743//mitochondrial inner membrane - GO:0009968//negative regulation of signal transduction;GO:0006259//DNA metabolic process gi|562821831|ref|XP_006140806.1|/6.8313e-43/PREDICTED: mitochondrial import inner membrane translocase subunit TIM16 isoform X2 [Tupaia chinensis] 109054 851.6 3.46 4.373333333 0.337961276 Up 0.381003422 Pfdn4 prefoldin 4 K09550|1|4e-46|187|rno:100366237|prefoldin subunit 4 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0051084//'de novo' posttranslational protein folding;GO:0044267//cellular protein metabolic process;GO:0051084//'de novo' posttranslational protein folding "gi|148674639|gb|EDL06586.1|/2.63156e-50/prefoldin 4, isoform CRA_c, partial [Mus musculus]" 18634 1894 13.36333333 15.47333333 0.211504105 Up 0.381003422 Pex7 peroxisomal biogenesis factor 7 K13341|1|4e-170|600|mmu:18634|peroxin-7 - - - - 14570 1032 0.1 0.44 2.137503524 Up 0.380965813 Arhgdig Rho GDP dissociation inhibitor (GDI) gamma K12462|1|9e-112|405|mmu:14570|Rho GDP-dissociation inhibitor GO:0044424 GO:0008047//enzyme activator activity;GO:0005488//binding;GO:0005092//GDP-dissociation inhibitor activity GO:0019222//regulation of metabolic process;GO:0008104//protein localization gi|6679989|ref|NP_032139.1|/7.79049e-111/rho GDP-dissociation inhibitor 3 [Mus musculus] 26386 1661.41 2.34 3.106666667 0.408858924 Up 0.380928203 Hsf4 heat shock transcription factor 4 K09417|1|0.0|799|mmu:26386|heat shock transcription factor 4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0070076//histone lysine demethylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0050896//response to stimulus;GO:0001654//eye development;GO:0030154//cell differentiation;GO:0051260//protein homooligomerization;GO:0050896//response to stimulus;GO:0001654//eye development;GO:0051260//protein homooligomerization;GO:0070076//histone lysine demethylation;GO:0030154//cell differentiation;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0070076//histone lysine demethylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0050896//response to stimulus;GO:0001654//eye development;GO:0030154//cell differentiation;GO:0051260//protein homooligomerization;GO:0050896//response to stimulus;GO:0001654//eye development;GO:0051260//protein homooligomerization;GO:0070076//histone lysine demethylation;GO:0030154//cell differentiation;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter gi|6754252|ref|NP_036069.1|/0/heat shock factor protein 4 isoform 2 [Mus musculus] 102639259 381 0.706666667 1.216666667 0.783832199 Up 0.380815375 Gm35612 "predicted gene, 35612" - - - - - 192292 2146 58.84333333 66.22666667 0.170533272 Up 0.38079657 Nrbp1 nuclear receptor binding protein 1 K08875|1|0.0|864|ocu:100348724|nuclear receptor-binding protein GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0032550;GO:0004672//protein kinase activity;GO:0042802//identical protein binding GO:0051403//stress-activated MAPK cascade;GO:0006464//cellular protein modification process;GO:0016482//cytosolic transport "gi|148705408|gb|EDL37355.1|/0/nuclear receptor binding protein, isoform CRA_b, partial [Mus musculus]" 68667 4245 6.423333333 7.69 0.259661432 Up 0.380664937 Trpm4 "transient receptor potential cation channel, subfamily M, member 4" K04979|1|0.0|2157|mmu:68667|transient receptor potential cation channel subfamily M member 4 GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0032550;GO:0005515//protein binding;GO:0005261//cation channel activity GO:0006816//calcium ion transport;GO:0008283//cell proliferation;GO:0002369//T cell cytokine production;GO:0034220//ion transmembrane transport;GO:0032446//protein modification by small protein conjugation;GO:0006873//cellular ion homeostasis;GO:0030595//leukocyte chemotaxis;GO:0030177//positive regulation of Wnt signaling pathway "gi|148690890|gb|EDL22837.1|/0/transient receptor potential cation channel, subfamily M, member 4, isoform CRA_c, partial [Mus musculus]" 66674 4144 6.44 7.713333333 0.26029377 Up 0.380664937 Spryd7 SPRY domain containing 7 - - - - gi|890769858|ref|NP_001297532.1|/1.53432e-86/SPRY domain-containing protein 7 isoform 2 [Mus musculus] 71881 2190 16.39666667 18.89333333 0.204474703 Up 0.380664937 Apmap adipocyte plasma membrane associated protein K17702|1|1e-139|499|fch:102046106|signal-induced proliferation-associated 1 like protein 2;K01757|2|3e-42|176|dme:Dmel_CG11833|strictosidine synthase [EC:4.3.3.2] GO:0044464;GO:0031224//intrinsic component of membrane GO:0016843;GO:0052689//carboxylic ester hydrolase activity GO:0008152//metabolic process gi|21313668|ref|NP_082253.1|/0/adipocyte plasma membrane-associated protein [Mus musculus] 74760 2320 4.553333333 5.606666667 0.300220222 Up 0.380608522 Rab3il1 RAB3A interacting protein (rabin3)-like 1 K16779|1|0.0|753|mmu:74760|Rab-3A-interacting protein - GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0019899//enzyme binding GO:0019222//regulation of metabolic process;GO:0045184//establishment of protein localization gi|21362337|ref|NP_653121.1|/0/guanine nucleotide exchange factor for Rab-3A [Mus musculus] 20312 3144 5.373333333 6.523333333 0.279792012 Up 0.380589718 Cx3cl1 chemokine (C-X3-C motif) ligand 1 K05508|1|0.0|682|mmu:20312|C-X3-C motif chemokine 1 GO:0031224//intrinsic component of membrane;GO:0044421;GO:0044444//cytoplasmic part GO:0005125//cytokine activity GO:0001525//angiogenesis;GO:0060078//regulation of postsynaptic membrane potential;GO:0007166//cell surface receptor signaling pathway;GO:0050663//cytokine secretion;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0006915//apoptotic process;GO:0019229//regulation of vasoconstriction;GO:0045123//cellular extravasation;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0032905;GO:0008284//positive regulation of cell proliferation;GO:0006954//inflammatory response;GO:0001775//cell activation gi|31982017|ref|NP_033168.2|/0/fractalkine precursor [Mus musculus] 68877 1696.53 57.56666667 64.79 0.170537481 Up 0.380429877 Maf1 "MAF1 homolog, negative regulator of RNA polymerase III" - - - - - 77590 4265 4.113333333 3.23 -0.348773824 Down 0.380420475 Chst15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 K08106|1|0.0|1167|mmu:77590|N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase [EC:2.8.2.33] GO:0031224//intrinsic component of membrane;GO:0012505//endomembrane system GO:0032550;GO:0008146//sulfotransferase activity GO:0006024//glycosaminoglycan biosynthetic process;GO:0019318//hexose metabolic process;GO:0006790//sulfur compound metabolic process gi|28972305|dbj|BAC65606.1|/0/mKIAA0598 protein [Mus musculus] 71238 550 11.02 9.386666667 -0.231439391 Down 0.380232427 Sdhaf3 succinate dehydrogenase complex assembly factor 3 - - - - - 17314 857 7.136666667 8.503333333 0.252778103 Up 0.380110196 Mgmt O-6-methylguanine-DNA methyltransferase K00567|1|1e-113|411|mmu:17314|methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] GO:0043231//intracellular membrane-bounded organelle GO:0008172//S-methyltransferase activity;GO:0046872//metal ion binding GO:0006979//response to oxidative stress;GO:0006281//DNA repair;GO:0097305//response to alcohol;GO:0010212//response to ionizing radiation;GO:0006915//apoptotic process;GO:0014070//response to organic cyclic compound;GO:0030855//epithelial cell differentiation gi|568949755|ref|XP_006507469.1|/4.91385e-115/PREDICTED: methylated-DNA--protein-cysteine methyltransferase isoform X3 [Mus musculus] 19358 2098.91 55.40666667 62.48333333 0.173411844 Up 0.380081989 Rad23a "RAD23 homolog A, nucleotide excision repair protein" K10839|1|6e-164|580|mmu:19358|UV excision repair protein RAD23 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0043130//ubiquitin binding;GO:0043566//structure-specific DNA binding;GO:0043130//ubiquitin binding;GO:0003677//DNA binding;GO:0043130//ubiquitin binding;GO:0043566//structure-specific DNA binding GO:0019079//viral genome replication;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006281//DNA repair;GO:0061136//regulation of proteasomal protein catabolic process;GO:0019079//viral genome replication;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006281//DNA repair;GO:0061136//regulation of proteasomal protein catabolic process;GO:0019079//viral genome replication;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006281//DNA repair;GO:0061136//regulation of proteasomal protein catabolic process "gi|148679012|gb|EDL10959.1|/2.26455e-163/RAD23a homolog (S. cerevisiae), isoform CRA_a, partial [Mus musculus]" 224705 2766 30.99666667 35.22666667 0.184554887 Up 0.380016172 Vps52 VPS52 GARP complex subunit K20298|1|0.0|1311|mmu:224705|vacuolar protein sorting-associated protein 52 GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0045184//establishment of protein localization;GO:0007398//ectoderm development;GO:0007439//ectodermal digestive tract development gi|148747162|ref|NP_766208.2|/0/vacuolar protein sorting-associated protein 52 homolog [Mus musculus] 69171 2738 13.30666667 15.38333333 0.209218927 Up 0.379997367 Cnppd1 cyclin Pas1/PHO80 domain containing 1 "K14612|1|2e-47|194|asn:102369244|solute carrier family 23 (nucleobase transporter), member 3" GO:0031224//intrinsic component of membrane GO:0019900//kinase binding - gi|29789185|ref|NP_081253.1|/0/protein CNPPD1 [Mus musculus] 215114 7883 13.06 11.24666667 -0.215657424 Down 0.379987965 Hip1 huntingtin interacting protein 1 K04559|1|0.0|1919|mmu:215114|huntingtin interacting protein 1 GO:0030117//membrane coat;GO:0030135//coated vesicle;GO:0031224//intrinsic component of membrane GO:0005543//phospholipid binding;GO:0008092//cytoskeletal protein binding "GO:0006351//transcription, DNA-templated;GO:0006901//vesicle coating;GO:0006898//receptor-mediated endocytosis;GO:0006915//apoptotic process;GO:0012502//induction of programmed cell death;GO:0048869//cellular developmental process" gi|225007582|ref|NP_666113.2|/0/huntingtin-interacting protein 1 [Mus musculus] 74558 8846 0.616666667 1.103333333 0.839305946 Up 0.379940953 Gvin1 "GTPase, very large interferon inducible 1" K06551|1|3e-74|284|xtr:101733039|signal-regulatory protein alpha/beta1/gamma;K12797|2|1e-16|93.2|myb:102249258|caspase recruitment domain-containing protein 6 - - - gi|115270958|ref|NP_083276.2|/0/interferon-induced very large GTPase 1 [Mus musculus] 14013 3818.3 2.946666667 2.21 -0.415037499 Down 0.379940953 Mecom MDS1 and EVI1 complex locus K04462|1|0.0|1404|bacu:103008158|ecotropic virus integration site 1 protein GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0042802//identical protein binding GO:0006366//transcription from RNA polymerase II promoter;GO:0012501//programmed cell death;GO:0007507//heart development;GO:0051707//response to other organism;GO:0008283//cell proliferation;GO:0030326//embryonic limb morphogenesis;GO:0001655//urogenital system development;GO:0007254//JNK cascade;GO:0007420//brain development;GO:0048869//cellular developmental process;GO:0006952//defense response;GO:0007049//cell cycle;GO:0001776//leukocyte homeostasis gi|568920750|ref|XP_006535450.1|/2.69753e-61/PREDICTED: MDS1 and EVI1 complex locus protein EVI1 isoform X3 [Mus musculus] 230594 6054 2.826666667 3.66 0.372741884 Up 0.379922148 Zcchc11 "zinc finger, CCHC domain containing 11" K13291|1|0.0|2897|mmu:230594|terminal uridylyltransferase [EC:2.7.7.52] - - - "gi|187956551|gb|AAI50792.1|/0/Zinc finger, CCHC domain containing 11 [Mus musculus]" 66052 1179 452.2366667 504.0833333 0.156584286 Up 0.379922148 Sdhc "succinate dehydrogenase complex, subunit C, integral membrane protein" K00236|1|2e-82|308|mmu:66052|succinate dehydrogenase (ubiquinone) cytochrome b560 subunit GO:0043234//protein complex;GO:0031224//intrinsic component of membrane;GO:0005746//mitochondrial respiratory chain "GO:0046906//tetrapyrrole binding;GO:0043169//cation binding;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors" GO:0009060//aerobic respiration;GO:0051234//establishment of localization;GO:0022900//electron transport chain "gi|228008307|ref|NP_079597.2|/1.58271e-81/succinate dehydrogenase cytochrome b560 subunit, mitochondrial precursor [Mus musculus]" 69724 2044 6.506666667 7.77 0.255995952 Up 0.379828124 Rnaseh2a "ribonuclease H2, large subunit" K10743|1|2e-173|612|mmu:69724|ribonuclease H2 subunit A [EC:3.1.26.4] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle "GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters" GO:0016070//RNA metabolic process gi|58037175|ref|NP_081463.1|/1.41627e-172/ribonuclease H2 subunit A [Mus musculus] 50779 5993.96 3.03 3.88 0.356738859 Up 0.37980932 Rgs6 regulator of G-protein signaling 6 K16449|1|0.0|917|mmu:50779|regulator of G-protein signaling - - - - 74149 2944 1.063333333 0.583333333 -0.866201502 Down 0.37977171 Zfp946 zinc finger protein 946 K09228|1|0.0|1129|mmu:74149|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|37574094|ref|NP_932120.1|/0/zinc finger protein 946 [Mus musculus] 12033 1811.48 9.516666667 11.13333333 0.226357357 Up 0.37977171 Bcap29 B cell receptor associated protein 29 K05545|1|2e-89|332|mcf:102116116|tRNA-dihydrouridine synthase 4 [EC:1.3.1.90];K14009|2|2e-44|183|pps:100976022|B-cell receptor-associated protein 31 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0012501//programmed cell death;GO:0015031//protein transport;GO:0012501//programmed cell death;GO:0015031//protein transport "gi|148704963|gb|EDL36910.1|/2.31687e-116/B-cell receptor-associated protein 29, partial [Mus musculus]" 26377 2973 1.32 1.933333333 0.55055247 Up 0.37961187 Dapp1 dual adaptor for phosphotyrosine and 3-phosphoinositides 1 K12229|1|7e-164|580|mmu:26377|dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0019207//kinase regulator activity;GO:0008289//lipid binding;GO:0004721//phosphoprotein phosphatase activity;GO:0043168//anion binding;GO:0019207//kinase regulator activity;GO:0008289//lipid binding;GO:0004721//phosphoprotein phosphatase activity;GO:0043168//anion binding GO:0006470//protein dephosphorylation;GO:0007154//cell communication;GO:0006470//protein dephosphorylation;GO:0007154//cell communication gi|6753604|ref|NP_036062.1|/5.70747e-163/dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform 1 [Mus musculus] 13000 3766 4.43 5.47 0.304234134 Up 0.379583662 Csnk2a2 "casein kinase 2, alpha prime polypeptide" K03097|1|0.0|650|mmu:13000|casein kinase II subunit alpha [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0032550;GO:0005515//protein binding;GO:0004672//protein kinase activity "GO:0006351//transcription, DNA-templated;GO:0007166//cell surface receptor signaling pathway;GO:0012501//programmed cell death;GO:0006796//phosphate-containing compound metabolic process;GO:0006935//chemotaxis;GO:0006464//cellular protein modification process;GO:0007093//mitotic cell cycle checkpoint" gi|6753540|ref|NP_034104.1|/0/casein kinase II subunit alpha' [Mus musculus] 217715 1605 21.28333333 24.34 0.193605049 Up 0.379499041 Eif2b2 "eukaryotic translation initiation factor 2B, subunit 2 beta" K03754|1|0.0|696|mmu:217715|translation initiation factor eIF-2B subunit beta - - - - 72318 2791 3.673333333 4.603333333 0.325589096 Up 0.379386212 Cyth4 cytohesin 4 K18441|1|0.0|810|mmu:72318|cytohesin - - - gi|60359808|dbj|BAD90123.1|/0/mFLJ00017 protein [Mus musculus] 65020 3549 7.106666667 8.463333333 0.252052957 Up 0.379348603 Zfp110 zinc finger protein 110 K12458|1|0.0|1672|mmu:65020|zinc finger protein 274 GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0005165//neurotrophin receptor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0012501//programmed cell death;GO:0070997//neuron death;GO:0007254//JNK cascade;GO:0007049//cell cycle;GO:0044764;GO:0006351//transcription, DNA-templated" "gi|148706149|gb|EDL38096.1|/0/mCG21533, partial [Mus musculus]" 226527 1289 7.283333333 8.64 0.246432438 Up 0.379348603 BC026585 cDNA sequence BC026585 K03650|1|6e-96|353|cmk:103184790|tRNA modification GTPase [EC:3.6.-.-];K00344|2|4e-77|291|nve:NEMVE_v1g238856|NADPH2:quinone reductase [EC:1.6.5.5] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0044710 gi|85701628|ref|NP_001028456.1|/0/quinone oxidoreductase-like protein 2 [Mus musculus] 26388 1796 0.633333333 1.126666667 0.831023828 Up 0.379348603 Ifi202b interferon activated gene 202B K12971|1|0.0|895|mmu:26388|interferon-activable protein 202;K12966|3|3e-39|165|ecb:100057148|absent in melanoma 2 GO:0005654//nucleoplasm;GO:0005654//nucleoplasm "GO:0005515//protein binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0043566//structure-specific DNA binding;GO:0005515//protein binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0043566//structure-specific DNA binding" GO:0001649//osteoblast differentiation;GO:0048519;GO:0006366//transcription from RNA polymerase II promoter;GO:0048518;GO:0043583//ear development;GO:0072331//signal transduction by p53 class mediator;GO:2000116//regulation of cysteine-type endopeptidase activity;GO:0097193//intrinsic apoptotic signaling pathway;GO:0050776//regulation of immune response;GO:0044092//negative regulation of molecular function;GO:0051704;GO:0031347//regulation of defense response;GO:0033554//cellular response to stress;GO:0035456//response to interferon-beta;GO:0001649//osteoblast differentiation;GO:0048519;GO:0006366//transcription from RNA polymerase II promoter;GO:0048518;GO:0043583//ear development;GO:0072331//signal transduction by p53 class mediator;GO:2000116//regulation of cysteine-type endopeptidase activity;GO:0097193//intrinsic apoptotic signaling pathway;GO:0050776//regulation of immune response;GO:0044092//negative regulation of molecular function;GO:0051704;GO:0031347//regulation of defense response;GO:0033554//cellular response to stress;GO:0035456//response to interferon-beta gi|164518893|ref|NP_036070.2|/0/interferon-activable protein 202 [Mus musculus] 72580 2364 0.836666667 1.366666667 0.707936546 Up 0.379245177 Zufsp zinc finger with UFM1-specific peptidase domain K09228|1|9e-06|55.1|cfo:105252557|KRAB domain-containing zinc finger protein GO:0044464 GO:0046914//transition metal ion binding - gi|30794380|ref|NP_082563.1|/0/zinc finger with UFM1-specific peptidase domain protein [Mus musculus] 67775 1573 11.01666667 12.80333333 0.216831692 Up 0.379104141 Rtp4 receptor transporter protein 4 - GO:0044424;GO:0031224//intrinsic component of membrane - GO:0006605//protein targeting gi|257196211|ref|NP_075875.3|/1.52906e-120/receptor-transporting protein 4 [Mus musculus] 106522 2454 10.71333333 12.50333333 0.222905334 Up 0.379104141 Pkdcc "protein kinase domain containing, cytoplasmic" "K17548|1|0.0|791|mmu:106522|protein kinase domain-containing protein, cytoplasmic" - - - - 68170 2269 13.16333333 15.21333333 0.208811424 Up 0.379038324 B230118H07Rik RIKEN cDNA B230118H07 gene - - - - "gi|148695706|gb|EDL27653.1|/2.34098e-139/RIKEN cDNA B230118H07, isoform CRA_c, partial [Mus musculus]" 67103 2104 0.896666667 1.433333333 0.676730487 Up 0.378963105 Ptgr1 prostaglandin reductase 1 K13948|1|0.0|637|mmu:67103|prostaglandin reductase 1 [EC:1.3.1.74 1.3.1.48] GO:0044424 "GO:0046914//transition metal ion binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0006692;GO:0042221//response to chemical gi|13385466|ref|NP_080244.1|/4.26573e-180/prostaglandin reductase 1 [Mus musculus] 72050 2324 6.333333333 7.583333333 0.259867127 Up 0.378953703 Kdelc1 KDEL (Lys-Asp-Glu-Leu) containing 1 K13667|1|4e-38|162|cjc:100392996|protein glucosyltransferase [EC:2.4.1.-] GO:0044432 - - gi|12963767|ref|NP_076134.1|/0/KDEL motif-containing protein 1 precursor [Mus musculus] 107029 2455 5.14 4.143333333 -0.310976469 Down 0.378859679 Me2 "malic enzyme 2, NAD(+)-dependent, mitochondrial" K00027|1|0.0|1184|mmu:107029|malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0004470//malic enzyme activity;GO:0000166//nucleotide binding GO:0043648//dicarboxylic acid metabolic process "gi|569002959|ref|XP_006525559.1|/0/PREDICTED: NAD-dependent malic enzyme, mitochondrial isoform X1 [Mus musculus]" 98952 4217 9.516666667 8.053333333 -0.240870291 Down 0.378840874 Fam102a "family with sequence similarity 102, member A" - - - - gi|958774474|ref|XP_014719110.1|/1.56192e-173/PREDICTED: protein FAM102A isoform X1 [Equus asinus] 68955 7476 4.793333333 3.843333333 -0.318671163 Down 0.378652826 Srrm4 serine/arginine repetitive matrix 4 - GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding GO:0008380//RNA splicing;GO:0048731//system development;GO:0050954//sensory perception of mechanical stimulus;GO:0048869//cellular developmental process gi|755513860|ref|XP_011246541.1|/1.24125e-92/PREDICTED: serine/arginine repetitive matrix protein 4 isoform X2 [Mus musculus] 16188 1394 4.433333333 5.46 0.300509111 Up 0.378436572 Il3ra "interleukin 3 receptor, alpha chain" K04737|1|0.0|763|mmu:16188|interleukin 3 receptor alpha GO:0031224//intrinsic component of membrane - - gi|755546870|ref|XP_011243035.1|/0/PREDICTED: interleukin-3 receptor subunit alpha isoform X2 [Mus musculus] 100041735 1743 0.163333333 0.52 1.670692375 Up 0.37838956 Gm3488 "predicted gene, 3488" "K03844|1|3e-16|89.4|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - gi|379642572|ref|NP_001229870.2|/1.0244e-128/alpha21-takusan [Mus musculus] 13821 6237.13 3.456666667 2.66 -0.377955243 Down 0.378286133 Epb41l1 erythrocyte membrane protein band 4.1 like 1 K06107|1|0.0|1596|mmu:13821|erythrocyte membrane protein band 4.1 GO:0043232;GO:0044425;GO:0032991//macromolecular complex;GO:0043232;GO:0044425;GO:0032991//macromolecular complex;GO:0043232;GO:0044425;GO:0032991//macromolecular complex;GO:0043232;GO:0044425;GO:0032991//macromolecular complex GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0030036//actin cytoskeleton organization;GO:0030036//actin cytoskeleton organization;GO:0030036//actin cytoskeleton organization;GO:0030036//actin cytoskeleton organization gi|597955325|ref|NP_001278052.1|/0/band 4.1-like protein 1 isoform e [Mus musculus] 319894 830 1.94 1.333333333 -0.541019153 Down 0.378248524 E330017L17Rik RIKEN cDNA E330017L17 gene - - - - - 320473 6437 6.24 7.483333333 0.26213501 Up 0.378220317 Heatr5b HEAT repeat containing 5B - - - - gi|124487157|ref|NP_001074648.1|/0/HEAT repeat-containing protein 5B [Mus musculus] 18617 869 2.473333333 1.796666667 -0.461133914 Down 0.37811689 Rhox5 reproductive homeobox 5 - GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding GO:0048870//cell motility;GO:0003006//developmental process involved in reproduction;GO:0006366//transcription from RNA polymerase II promoter gi|1709629|sp|P52651.1|RHOX5_MOUSE/2.3674e-80/RecName: Full=Homeobox protein Rhox5; AltName: Full=Homeobox protein Pem; AltName: Full=Placenta and embryonic expression protein; AltName: Full=Reproductive homeobox on chromosome X 5 100503849 1147 1.616666667 2.27 0.489670051 Up 0.378098086 Sp3os "trans-acting transcription factor 3, opposite strand" - - - - "gi|148695172|gb|EDL27119.1|/1.05666e-39/mCG1039900, isoform CRA_a [Mus musculus]" 270076 2171.13 30.07666667 34.03333333 0.178303775 Up 0.378032269 Gcdh glutaryl-Coenzyme A dehydrogenase K00252|1|0.0|820|mmu:270076|glutaryl-CoA dehydrogenase [EC:1.3.8.6] GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0003995//acyl-CoA dehydrogenase activity;GO:0000166//nucleotide binding;GO:0003995//acyl-CoA dehydrogenase activity;GO:0000166//nucleotide binding GO:0006631//fatty acid metabolic process;GO:0035337;GO:0006631//fatty acid metabolic process;GO:0035337 "gi|148679020|gb|EDL10967.1|/0/glutaryl-Coenzyme A dehydrogenase, isoform CRA_a, partial [Mus musculus]" 319931 1919 2.486666667 3.266666667 0.393606119 Up 0.378004062 A330032B11Rik RIKEN cDNA A330032B11 gene - - - - "gi|148709833|gb|EDL41779.1|/7.97348e-29/mCG146173, partial [Mus musculus]" 67788 1583 50.92333333 57.25 0.168948835 Up 0.37795705 Sfr1 SWI5 dependent recombination repair 1 - GO:0000790//nuclear chromatin - GO:0000725//recombinational repair gi|569007742|ref|XP_006527371.1|/3.82268e-95/PREDICTED: swi5-dependent recombination DNA repair protein 1 homolog isoform X1 [Mus musculus] 319165 535 0.01 0.243333333 4.604862058 Up 0.377947648 Hist1h2ad "histone cluster 1, H2ad" K11251|1|7e-54|211|ecb:100053897|histone H2A - - - - 666244 439 0.24 0.01 -4.584962501 Down 0.377947648 Tmsb15b1 thymosin beta 15b1 "K05764|1|7e-11|67.8|amj:102577269|thymosin, beta 4" GO:0005884//actin filament GO:0003779//actin binding GO:0030837//negative regulation of actin filament polymerization;GO:0032232//negative regulation of actin filament bundle assembly "gi|148691934|gb|EDL23881.1|/2.73608e-32/RIKEN cDNA 4930488E11, partial [Mus musculus]" 18938 919 34.11333333 30.16333333 -0.177539864 Down 0.377938245 Ppp1r14b "protein phosphatase 1, regulatory (inhibitor) subunit 14B" K17555|1|1e-50|202|pale:102882711|protein phosphatase 1 regulatory subunit 14B - - - "gi|989935538|ref|XP_015444176.1|/1.07142e-49/PREDICTED: protein phosphatase 1 regulatory subunit 14B, partial [Pteropus alecto]" 14870 744 237.2566667 265.2066667 0.160668416 Up 0.377928843 Gstp1 "glutathione S-transferase, pi 1" K00799|1|7e-120|431|mmu:14870|glutathione S-transferase [EC:2.5.1.18] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane "GO:0030234//enzyme regulator activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0072341//modified amino acid binding;GO:0019901//protein kinase binding" GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0032868//response to insulin;GO:0006915//apoptotic process;GO:0032611//interleukin-1 beta production;GO:0021782//glial cell development;GO:0051384//response to glucocorticoid;GO:0031668//cellular response to extracellular stimulus;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0006979//response to oxidative stress;GO:0032682//negative regulation of chemokine production;GO:0002526//acute inflammatory response;GO:0070265//necrotic cell death;GO:0070849//response to epidermal growth factor;GO:0032872//regulation of stress-activated MAPK cascade;GO:0006790//sulfur compound metabolic process;GO:0043407//negative regulation of MAP kinase activity;GO:0001101//response to acid chemical;GO:0043627//response to estrogen;GO:0010038//response to metal ion;GO:0008285//negative regulation of cell proliferation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0033273//response to vitamin;GO:0051354//negative regulation of oxidoreductase activity;GO:0010558;GO:0097305//response to alcohol;GO:0032496//response to lipopolysaccharide;GO:0009887//organ morphogenesis gi|10092608|ref|NP_038569.1|/5.53632e-119/glutathione S-transferase P 1 [Mus musculus] 16554 5603 1.19 0.693333333 -0.779340546 Down 0.377656174 Kif13b kinesin family member 13B K17914|1|0.0|3371|mmu:16554|kinesin family member 13 GO:0015630//microtubule cytoskeleton;GO:0043005//neuron projection GO:0032550;GO:0019900//kinase binding;GO:0003774//motor activity GO:0007409//axonogenesis;GO:0006928//movement of cell or subcellular component gi|124487163|ref|NP_001074646.1|/0/kinesin-like protein KIF13B [Mus musculus] 212647 3355 49.75333333 55.99666667 0.170547765 Up 0.377646771 Aldh4a1 "aldehyde dehydrogenase 4 family, member A1" K00294|1|0.0|1090|mmu:212647|1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88] GO:0044429 "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0005515//protein binding" GO:0019471//4-hydroxyproline metabolic process;GO:0006560//proline metabolic process;GO:0006536//glutamate metabolic process "gi|148681366|gb|EDL13313.1|/0/aldehyde dehydrogenase 4 family, member A1, isoform CRA_c, partial [Mus musculus]" 18643 883 227.9366667 254.19 0.157274255 Up 0.377618564 Pfn1 profilin 1 K05759|1|7e-77|279|chx:102175326|profilin GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0043232 GO:0008092//cytoskeletal protein binding;GO:0017016//Ras GTPase binding;GO:0043168//anion binding GO:0070848//response to growth factor;GO:0032233//positive regulation of actin filament bundle assembly;GO:0014020;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006259//DNA metabolic process;GO:0030837//negative regulation of actin filament polymerization gi|926716336|ref|XP_005693514.2|/5.84161e-76/PREDICTED: profilin-1 [Capra hircus] 57743 2369 5.14 6.256666667 0.283625885 Up 0.377609162 Sec61a2 "Sec61, alpha subunit 2 (S. cerevisiae)" K10956|1|0.0|938|pale:102895305|protein transport protein SEC61 subunit alpha GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0043021//ribonucleoprotein complex binding GO:0044763;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0045184//establishment of protein localization gi|10946604|ref|NP_067280.1|/0/protein transport protein Sec61 subunit alpha isoform 2 [Mus musculus] 66838 619 6.37 5.253333333 -0.278060244 Down 0.377609162 0610009L18Rik RIKEN cDNA 0610009L18 gene - - - - - 67420 4339 2.323333333 1.663333333 -0.482118841 Down 0.377552747 Far1 fatty acyl CoA reductase 1 K13356|1|0.0|1011|tup:102474742|alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84] GO:0031224//intrinsic component of membrane;GO:0044439;GO:0031224//intrinsic component of membrane;GO:0044439 "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0036094//small molecule binding" GO:0006633//fatty acid biosynthetic process;GO:0046485//ether lipid metabolic process;GO:0035337;GO:0006650//glycerophospholipid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0046485//ether lipid metabolic process;GO:0035337;GO:0006650//glycerophospholipid metabolic process gi|625227327|ref|XP_007652948.1|/0/PREDICTED: fatty acyl-CoA reductase 1 isoform X2 [Cricetulus griseus] 229487 2307 20.96333333 23.88666667 0.188337408 Up 0.37752454 Gatb "glutamyl-tRNA(Gln) amidotransferase, subunit B" K02434|1|0.0|1106|mmu:229487|aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0032550;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor" GO:0006412//translation;GO:0043039//tRNA aminoacylation "gi|21450279|ref|NP_659145.1|/0/glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial precursor [Mus musculus]" 57813 2344.8 3.753333333 4.69 0.321415501 Up 0.377458724 Tk2 "thymidine kinase 2, mitochondrial" K00857|1|2e-118|244|mmu:57813|thymidine kinase [EC:2.7.1.21] GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0032550;GO:0019136//deoxynucleoside kinase activity;GO:0032550;GO:0019136//deoxynucleoside kinase activity GO:0009124//nucleoside monophosphate biosynthetic process;GO:0009117//nucleotide metabolic process;GO:0046125;GO:0006261//DNA-dependent DNA replication;GO:0000002//mitochondrial genome maintenance;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0009117//nucleotide metabolic process;GO:0046125;GO:0006261//DNA-dependent DNA replication;GO:0000002//mitochondrial genome maintenance gi|6424683|gb|AAF08104.1|AF105217_1/1.98669e-141/thymidine kinase 2 [Mus musculus] 228966 3272 4.403333333 5.426666667 0.301470233 Up 0.377223664 Ppp1r3d "protein phosphatase 1, regulatory subunit 3D" K07189|1|5e-140|501|mmu:228966|protein phosphatase 1 regulatory subunit 3A/B/C/D/E GO:0043227//membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0016791//phosphatase activity;GO:0005515//protein binding GO:0005980//glycogen catabolic process;GO:0005978//glycogen biosynthetic process gi|147905969|ref|NP_001078970.1|/4.69628e-139/protein phosphatase 1 regulatory subunit 3D [Mus musculus] 71986 1871 8.016666667 9.443333333 0.236293708 Up 0.377186054 Ddx28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 K20096|1|0.0|989|mmu:71986|ATP-dependent RNA helicase DDX28 [EC:3.6.4.13] GO:0005759//mitochondrial matrix;GO:0031981//nuclear lumen "GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550" - gi|12845809|dbj|BAB26907.1|/0/unnamed protein product [Mus musculus] 28185 3778 18.28333333 15.94666667 -0.197274231 Down 0.377176652 Tomm70a translocase of outer mitochondrial membrane 70 homolog A (yeast) K17768|1|0.0|978|mmu:28185|mitochondrial import receptor subunit TOM70 GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane - GO:0045184//establishment of protein localization gi|28972369|dbj|BAC65638.1|/0/mKIAA0719 protein [Mus musculus] 230979 893 1.656666667 1.09 -0.603955216 Down 0.377148445 Tnfrsf14 "tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)" K05152|1|1e-164|580|mmu:230979|tumor necrosis factor receptor superfamily member 14 GO:0009986//cell surface GO:0044389//ubiquitin-like protein ligase binding GO:0042130//negative regulation of T cell proliferation;GO:0042742//defense response to bacterium;GO:0001934//positive regulation of protein phosphorylation gi|30725810|ref|NP_849262.1|/1.0477e-163/tumor necrosis factor receptor superfamily member 14 precursor [Mus musculus] 73373 2104 14.79666667 12.80333333 -0.208752745 Down 0.377120238 Phospho2 "phosphatase, orphan 2" K13248|1|4e-128|461|mmu:73373|pyridoxal phosphate phosphatase PHOSPHO2 [EC:3.1.3.74] - GO:0016791//phosphatase activity;GO:0043169//cation binding GO:0006796//phosphate-containing compound metabolic process "gi|148695097|gb|EDL27044.1|/1.25625e-131/phosphatase, orphan 2, isoform CRA_a, partial [Mus musculus]" 215748 3448 14.66 12.67333333 -0.210089072 Down 0.377120238 Cnksr3 Cnksr family member 3 K17536|1|0.0|653|tru:101070876|connector enhancer of kinase suppressor of Ras 2 GO:0044424 - GO:0043409//negative regulation of MAPK cascade;GO:0001933//negative regulation of protein phosphorylation;GO:0002028//regulation of sodium ion transport gi|27369772|ref|NP_766134.1|/0/connector enhancer of kinase suppressor of ras 3 [Mus musculus] 19300 2527 4.766666667 5.83 0.290515142 Up 0.377054421 Abcd4 "ATP-binding cassette, sub-family D (ALD), member 4" "K05678|1|0.0|1127|mmu:19300|ATP-binding cassette, subfamily D (ALD), member 4" GO:0031224//intrinsic component of membrane;GO:0042579//microbody;GO:0031090//organelle membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0015405 GO:0006767//water-soluble vitamin metabolic process "gi|148670868|gb|EDL02815.1|/0/ATP-binding cassette, sub-family D (ALD), member 4, isoform CRA_e, partial [Mus musculus]" 17700 2705 0.216666667 0.593333333 1.453365618 Up 0.377007409 Mstn myostatin K05497|1|0.0|728|mmu:17700|growth differentiation factor 8/11 - - - - 106840 3643 10.30666667 12.03666667 0.223858101 Up 0.376950995 Unc119b unc-119 lipid binding chaperone B "K05291|1|3e-73|280|asn:102369943|phosphatidylinositol glycan, class S" GO:0031513//nonmotile primary cilium GO:0005488//binding GO:0048858//cell projection morphogenesis;GO:0015031//protein transport "gi|148687935|gb|EDL19882.1|/1.59741e-127/expressed sequence AA407659, isoform CRA_c, partial [Mus musculus]" 74238 1577 12.07666667 10.34333333 -0.223521109 Down 0.376950995 Mterf2 mitochondrial transcription termination factor 2 "K15031|1|0.0|725|mmu:74238|transcription termination factor, mitochondrial" GO:0005759//mitochondrial matrix GO:0000975//regulatory region DNA binding;GO:0042802//identical protein binding "GO:0006351//transcription, DNA-templated" "gi|148689467|gb|EDL21414.1|/0/MTERF domain containing 3, isoform CRA_a [Mus musculus]" 21881 3242 8.88 10.44 0.23349013 Up 0.376809959 Tkt transketolase K00615|1|0.0|1240|mmu:21881|transketolase [EC:2.2.1.1] GO:0031981//nuclear lumen;GO:0042579//microbody;GO:0031090//organelle membrane GO:0019842//vitamin binding;GO:0043169//cation binding;GO:0042802//identical protein binding;GO:0016744;GO:0030246//carbohydrate binding GO:0006098//pentose-phosphate shunt;GO:0019693//ribose phosphate metabolic process;GO:0040007//growth;GO:0019682//glyceraldehyde-3-phosphate metabolic process gi|6678359|ref|NP_033414.1|/0/transketolase [Mus musculus] 72368 2132.15 15.63666667 17.96333333 0.200122086 Up 0.376809959 Borcs8 BLOC-1 related complex subunit 8 - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0019899//enzyme binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0019899//enzyme binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0019899//enzyme binding "GO:0044767//single-organism developmental process;GO:0006351//transcription, DNA-templated;GO:0044767//single-organism developmental process;GO:0006351//transcription, DNA-templated;GO:0044767//single-organism developmental process;GO:0006351//transcription, DNA-templated" gi|830260324|ref|NP_001296574.1|/2.8152e-54/protein MEF2BNB isoform 2 [Mus musculus] 51789 3810.61 9.003333333 10.56333333 0.23053402 Up 0.376809959 Tnk2 "tyrosine kinase, non-receptor, 2" K08886|1|0.0|1004|mmu:51789|activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1] GO:0043005//neuron projection;GO:0016020//membrane;GO:0030135//coated vesicle;GO:0044297//cell body;GO:0043234//protein complex;GO:0012505//endomembrane system;GO:0043005//neuron projection;GO:0016020//membrane;GO:0030135//coated vesicle;GO:0044297//cell body;GO:0043234//protein complex;GO:0012505//endomembrane system;GO:0043005//neuron projection;GO:0016020//membrane;GO:0030135//coated vesicle;GO:0044297//cell body;GO:0043234//protein complex;GO:0012505//endomembrane system GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0019904//protein domain specific binding;GO:0070851//growth factor receptor binding;GO:0043169//cation binding;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0019904//protein domain specific binding;GO:0070851//growth factor receptor binding;GO:0043169//cation binding;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0019904//protein domain specific binding;GO:0070851//growth factor receptor binding;GO:0043169//cation binding GO:0001934//positive regulation of protein phosphorylation;GO:0048259//regulation of receptor-mediated endocytosis;GO:0001934//positive regulation of protein phosphorylation;GO:0048259//regulation of receptor-mediated endocytosis;GO:0001934//positive regulation of protein phosphorylation;GO:0048259//regulation of receptor-mediated endocytosis "gi|148665389|gb|EDK97805.1|/0/tyrosine kinase, non-receptor, 2, isoform CRA_e, partial [Mus musculus]" 94091 2279 9.116666667 10.68 0.228333315 Up 0.376809959 Trim11 tripartite motif-containing 11 K10650|1|0.0|837|mmu:94091|tripartite motif-containing protein 11 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity "GO:0032446//protein modification by small protein conjugation;GO:0002252;GO:0006351//transcription, DNA-templated;GO:0010721//negative regulation of cell development;GO:0032446//protein modification by small protein conjugation;GO:0002252;GO:0006351//transcription, DNA-templated;GO:0010721//negative regulation of cell development" gi|597436906|ref|NP_001277917.1|/0/E3 ubiquitin-protein ligase TRIM11 isoform 1 [Mus musculus] 19785 238 0.01 0.236666667 4.564784619 Up 0.376791154 Rprl3 ribonuclease P RNA-like 3 - - - - gi|426376198|ref|XP_004054894.1|/1.47912e-09/PREDICTED: uncharacterized protein LOC101140100 [Gorilla gorilla gorilla] 73435 809 0.01 0.236666667 4.564784619 Up 0.376791154 Tex35 testis expressed 35 - GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton - - "gi|148707420|gb|EDL39367.1|/4.75575e-117/mCG15959, isoform CRA_b, partial [Mus musculus]" 18407 773 0.01 0.236666667 4.564784619 Up 0.376791154 Orm3 orosomucoid 3 K17308|1|3e-75|283|mmu:18405|alpha-1-acid glycoprotein 1 GO:0005578//proteinaceous extracellular matrix GO:0005488//binding GO:0002437//inflammatory response to antigenic stimulus;GO:0060416//response to growth hormone;GO:0009887//organ morphogenesis;GO:0051384//response to glucocorticoid;GO:0002237//response to molecule of bacterial origin;GO:0032526//response to retinoic acid gi|62548316|ref|NP_038651.2|/1.09443e-104/alpha-1-acid glycoprotein 3 precursor [Mus musculus] 56708 1960 0.456666667 0.906666667 0.989430758 Up 0.37669713 Clcf1 cardiotrophin-like cytokine factor 1 K05421|1|3e-158|561|ngi:103725580|B-cell stimulating factor 3 GO:0044464;GO:0043234//protein complex;GO:0044421;GO:0044464;GO:0043234//protein complex;GO:0044421;GO:0044464;GO:0043234//protein complex;GO:0044421 GO:0005126//cytokine receptor binding;GO:0046983//protein dimerization activity;GO:0005126//cytokine receptor binding;GO:0046983//protein dimerization activity;GO:0005126//cytokine receptor binding;GO:0046983//protein dimerization activity GO:0006954//inflammatory response;GO:0043524//negative regulation of neuron apoptotic process;GO:0030098//lymphocyte differentiation;GO:0045687//positive regulation of glial cell differentiation;GO:0046887//positive regulation of hormone secretion;GO:0043408//regulation of MAPK cascade;GO:0045830//positive regulation of isotype switching;GO:0030888//regulation of B cell proliferation;GO:0002828//regulation of type 2 immune response;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0006954//inflammatory response;GO:0043524//negative regulation of neuron apoptotic process;GO:0030098//lymphocyte differentiation;GO:0045687//positive regulation of glial cell differentiation;GO:0046887//positive regulation of hormone secretion;GO:0043408//regulation of MAPK cascade;GO:0045830//positive regulation of isotype switching;GO:0030888//regulation of B cell proliferation;GO:0002828//regulation of type 2 immune response;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0006954//inflammatory response;GO:0043524//negative regulation of neuron apoptotic process;GO:0030098//lymphocyte differentiation;GO:0045687//positive regulation of glial cell differentiation;GO:0046887//positive regulation of hormone secretion;GO:0043408//regulation of MAPK cascade;GO:0045830//positive regulation of isotype switching;GO:0030888//regulation of B cell proliferation;GO:0002828//regulation of type 2 immune response;GO:0042503//tyrosine phosphorylation of Stat3 protein gi|533139327|ref|XP_005384395.1|/2.51945e-167/PREDICTED: cardiotrophin-like cytokine factor 1 isoform X1 [Chinchilla lanigera] 78689 2646 17.95333333 15.63666667 -0.199318729 Down 0.376621911 Naa35 "N(alpha)-acetyltransferase 35, NatC auxiliary subunit" - GO:0016020//membrane;GO:0031981//nuclear lumen - GO:0033002//muscle cell proliferation "gi|172072615|ref|NP_084429.2|/0/N-alpha-acetyltransferase 35, NatC auxiliary subunit [Mus musculus]" 216705 3398 23.63666667 20.78666667 -0.185368168 Down 0.376471473 Clint1 clathrin interactor 1 K12471|1|3e-172|608|xla:494733|epsin - - - gi|154240730|ref|NP_001038985.2|/0/clathrin interactor 1 [Mus musculus] 66171 898.17 46.39333333 52.30333333 0.172985387 Up 0.376462071 Pgls 6-phosphogluconolactonase K01057|1|4e-86|320|mmu:66171|6-phosphogluconolactonase [EC:3.1.1.31] - GO:0030246//carbohydrate binding;GO:0052689//carboxylic ester hydrolase activity;GO:0030246//carbohydrate binding;GO:0052689//carboxylic ester hydrolase activity GO:0006098//pentose-phosphate shunt;GO:0006098//pentose-phosphate shunt "gi|149036104|gb|EDL90770.1|/1.47747e-151/6-phosphogluconolactonase (predicted), isoform CRA_a [Rattus norvegicus]" 228769 3559 7 8.306666667 0.24691474 Up 0.376368047 Psmf1 "proteasome (prosome, macropain) inhibitor subunit 1" K06700|1|3e-159|565|mmu:228769|proteasome inhibitor subunit 1 (PI31) - - - - 211039 807 0.513333333 0.973333333 0.923038018 Up 0.376330437 BC016548 cDNA sequence BC016548 - - - - - 68763 553.66 3.673333333 4.6 0.324544043 Up 0.376198804 1110038B12Rik RIKEN cDNA 1110038B12 gene - - - - - 56443 1588 28.72 32.48666667 0.177791973 Up 0.376189402 Arpc1a "actin related protein 2/3 complex, subunit 1A" "K05757|1|0.0|736|chx:102172116|actin related protein 2/3 complex, subunit 1A/1B" GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding GO:0008064//regulation of actin polymerization or depolymerization gi|926724242|ref|XP_005697938.2|/0/PREDICTED: actin-related protein 2/3 complex subunit 1A isoform X1 [Capra hircus] 18162 6779.43 1.236666667 1.826666667 0.562756706 Up 0.376057768 Npr3 natriuretic peptide receptor 3 K12325|1|2e-147|527|mmu:18162|atrial natriuretic peptide clearance receptor GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0031224//intrinsic component of membrane GO:0001653//peptide receptor activity;GO:0042802//identical protein binding;GO:0042277//peptide binding;GO:0001653//peptide receptor activity;GO:0042802//identical protein binding;GO:0042277//peptide binding;GO:0001653//peptide receptor activity;GO:0042802//identical protein binding;GO:0042277//peptide binding GO:0048731//system development;GO:0048017//inositol lipid-mediated signaling;GO:0007589//body fluid secretion;GO:0032770//positive regulation of monooxygenase activity;GO:0008015//blood circulation;GO:0035809;GO:0033687//osteoblast proliferation;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0070661//leukocyte proliferation;GO:0048731//system development;GO:0048017//inositol lipid-mediated signaling;GO:0007589//body fluid secretion;GO:0032770//positive regulation of monooxygenase activity;GO:0008015//blood circulation;GO:0035809;GO:0033687//osteoblast proliferation;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0070661//leukocyte proliferation;GO:0048731//system development;GO:0048017//inositol lipid-mediated signaling;GO:0007589//body fluid secretion;GO:0032770//positive regulation of monooxygenase activity;GO:0008015//blood circulation;GO:0035809;GO:0033687//osteoblast proliferation;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0070661//leukocyte proliferation "gi|148671332|gb|EDL03279.1|/0/natriuretic peptide receptor 3, isoform CRA_b, partial [Mus musculus]" 14030 2441.23 47.27333333 53.08 0.167141775 Up 0.376010756 Ewsr1 Ewing sarcoma breakpoint region 1 K13209|1|3e-85|319|mmu:14030|RNA-binding protein EWS GO:0005634//nucleus;GO:0005634//nucleus;GO:0016604//nuclear body GO:0005488//binding;GO:0005488//binding;GO:0097159//organic cyclic compound binding;GO:1901363//heterocyclic compound binding - "gi|148708571|gb|EDL40518.1|/5.3878e-55/mCG14699, isoform CRA_b, partial [Mus musculus]" 52163 1434 46.17 51.96 0.170445698 Up 0.375935537 Camk1 calcium/calmodulin-dependent protein kinase I K08794|1|0.0|692|rno:171503|calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0032550;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity GO:0051094//positive regulation of developmental process;GO:0051130//positive regulation of cellular component organization;GO:0010975//regulation of neuron projection development;GO:0006611//protein export from nucleus;GO:0007154//cell communication;GO:0045860//positive regulation of protein kinase activity;GO:0042692//muscle cell differentiation;GO:0051098//regulation of binding gi|564348142|ref|XP_006237062.1|/0/PREDICTED: calcium/calmodulin-dependent protein kinase type 1 isoform X3 [Rattus norvegicus] 66878 3661 15.27333333 17.56333333 0.201551721 Up 0.375822709 Riok3 RIO kinase 3 K08872|1|0.0|985|mmu:66878|RIO kinase 3 [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|110625737|ref|NP_077144.2|/0/serine/threonine-protein kinase RIO3 [Mus musculus] 55983 4106 17.33666667 15.05 -0.20406305 Down 0.375822709 Pdzrn3 PDZ domain containing RING finger 3 K15682|1|0.0|2020|mmu:55983|ligand of Numb protein X 3/4 [EC:2.3.2.27] GO:0045202//synapse GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0048741//skeletal muscle fiber development;GO:0032446//protein modification by small protein conjugation gi|256985136|ref|NP_061372.2|/0/E3 ubiquitin-protein ligase PDZRN3 [Mus musculus] 71918 4375 17.67666667 15.39 -0.199853016 Down 0.375822709 Zcchc24 "zinc finger, CCHC domain containing 24" - - GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0042063//gliogenesis gi|160333288|ref|NP_001094903.1|/2.0941e-129/zinc finger CCHC domain-containing protein 24 [Mus musculus] 24045 1577.4 45.63 51.36666667 0.170849802 Up 0.375681673 Scamp3 secretory carrier membrane protein 3 K19995|1|1e-134|482|mmu:24045|secretory carrier-associated membrane protein;K08823|5|2e-121|438|mmu:105943584|CDC-like kinase [EC:2.7.12.1] GO:0016020//membrane;GO:0016020//membrane - GO:0015031//protein transport;GO:0033993//response to lipid;GO:0015031//protein transport;GO:0033993//response to lipid;GO:0015031//protein transport;GO:0033993//response to lipid gi|12805127|gb|AAH02021.1|/3.19037e-134/Secretory carrier membrane protein 3 [Mus musculus] 19041 6277 1.626666667 1.063333333 -0.613324724 Down 0.375653466 Ppl periplakin K10386|1|0.0|2920|mmu:19041|periplakin GO:0019898//extrinsic component of membrane;GO:0043232;GO:0043231//intracellular membrane-bounded organelle - GO:0030216//keratinocyte differentiation gi|112421039|ref|NP_032935.2|/0/periplakin [Mus musculus] 66667 4606 0.313333333 0.713333333 1.186878135 Up 0.375484223 Hspbap1 Hspb associated protein 1 K19375|1|0.0|1009|mmu:66667|HSPB1-associated protein 1 - - - gi|120587017|ref|NP_780320.2|/0/HSPB1-associated protein 1 [Mus musculus] 228491 4276 3.706666667 2.89 -0.35905289 Down 0.375380797 Zfp770 zinc finger protein 770 K09228|1|2e-57|227|obi:106871808|KRAB domain-containing zinc finger protein - - - gi|30425204|ref|NP_780675.1|/0/zinc finger protein 770 [Mus musculus] 13030 4756 146.04 163.4666667 0.162632904 Up 0.375352589 Ctsb cathepsin B K01363|1|0.0|713|mmu:13030|cathepsin B [EC:3.4.22.1] - - - - 69066 1100 1.006666667 1.553333333 0.625781405 Up 0.375286773 1810010H24Rik RIKEN cDNA 1810010H24 gene - - - - gi|755539534|ref|XP_006534160.2|/1.47671e-78/PREDICTED: UPF0450 protein C17orf58 homolog isoform X3 [Mus musculus] 14470 875 141.5333333 158.32 0.161701647 Up 0.375108127 Rabac1 Rab acceptor 1 (prenylated) K20359|1|1e-102|375|mmu:14470|PRA1 family protein 1 GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic component of membrane GO:0005515//protein binding GO:0006810//transport gi|33859558|ref|NP_034391.1|/8.47395e-102/prenylated Rab acceptor protein 1 [Mus musculus] 246221 1304.32 19.2 21.96 0.193771743 Up 0.375098725 Mpst mercaptopyruvate sulfurtransferase K01011|1|2e-175|617|mmu:246221|thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection GO:0016783//sulfurtransferase activity;GO:0016783//sulfurtransferase activity;GO:0016783//sulfurtransferase activity GO:0044272//sulfur compound biosynthetic process;GO:0009439//cyanate metabolic process;GO:0042221//response to chemical;GO:0044272//sulfur compound biosynthetic process;GO:0009439//cyanate metabolic process;GO:0042221//response to chemical;GO:0044272//sulfur compound biosynthetic process;GO:0009439//cyanate metabolic process;GO:0042221//response to chemical gi|244789999|ref|NP_619611.3|/1.88966e-174/3-mercaptopyruvate sulfurtransferase [Mus musculus] 100306944 205 0.576666667 1.05 0.864579791 Up 0.37507992 Snora73a "small nucleolar RNA, H/ACA box 73a" K17585|1|5e-14|68.6|lve:103088203|phosphatase and actin regulator 4 - - - gi|602699793|ref|XP_007461897.1|/4.35593e-13/PREDICTED: phosphatase and actin regulator 4 [Lipotes vexillifer] 238505 4487 7.95 6.663333333 -0.254710794 Down 0.37507992 Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase K00548|1|0.0|2512|mmu:238505|5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] GO:0044424 GO:0019842//vitamin binding;GO:0008172//S-methyltransferase activity;GO:0046914//transition metal ion binding;GO:0031406//carboxylic acid binding GO:0000097//sulfur amino acid biosynthetic process;GO:0097305//response to alcohol;GO:0008213;GO:0006760//folic acid-containing compound metabolic process gi|124487479|ref|NP_001074597.1|/0/methionine synthase [Mus musculus] 84505 4644 3.116666667 3.96 0.345496566 Up 0.374891873 Setdb1 "SET domain, bifurcated 1" K11421|1|0.0|2232|mmu:84505|histone-lysine N-methyltransferase SETDB1 [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0016279//protein-lysine N-methyltransferase activity "GO:0001501//skeletal system development;GO:0006351//transcription, DNA-templated;GO:0016571//histone methylation;GO:0001501//skeletal system development;GO:0006351//transcription, DNA-templated;GO:0016571//histone methylation;GO:0001501//skeletal system development;GO:0006351//transcription, DNA-templated;GO:0016571//histone methylation" "gi|148706861|gb|EDL38808.1|/0/mCG16729, isoform CRA_b, partial [Mus musculus]" 16651 4369.84 51.05 45.51333333 -0.16562171 Down 0.374835458 Sspn sarcospan - - - - gi|568944124|ref|XP_006506979.1|/2.1704e-70/PREDICTED: sarcospan isoform X1 [Mus musculus] 383787 4861 0.486666667 0.936666667 0.944601761 Up 0.374769642 Ankrd63 ankyrin repeat domain 63 K10799|1|1e-13|82.4|pxy:105390121|tankyrase [EC:2.4.2.30];K15502|4|3e-13|81.3|tru:101061946|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A - - - gi|126517480|ref|NP_001075440.1|/2.09768e-170/ankyrin repeat domain-containing protein 63 [Mus musculus] 13854 2541.63 134.59 150.3966667 0.16020137 Up 0.37468502 Epn1 epsin 1 K12471|1|0.0|789|mmu:13854|epsin - - - - 320642 1253 0.763333333 1.27 0.734443399 Up 0.374534582 A630066F11Rik RIKEN cDNA A630066F11 gene - - - - - 14910 743.51 4.04 5 0.307572802 Up 0.374421753 Gt(ROSA)26Sor "gene trap ROSA 26, Philippe Soriano" - - GO:0003676//nucleic acid binding;GO:0016741 GO:0008152//metabolic process "gi|148667020|gb|EDK99436.1|/7.25525e-08/mCG145848, partial [Mus musculus]" 751554 84 0.73 1.23 0.752689946 Up 0.374384144 Mir678 microRNA 678 - - - - - 212427 2214 1.653333333 1.093333333 -0.596644306 Down 0.374337132 A730008H23Rik RIKEN cDNA A730008H23 gene - GO:0031981//nuclear lumen;GO:0000776//kinetochore GO:0005515//protein binding GO:0006461//protein complex assembly;GO:0043486//histone exchange;GO:0051098//regulation of binding gi|27369700|ref|NP_766093.1|/0/Holliday junction recognition protein [Mus musculus] 56371 2258 19.29 21.99666667 0.189431774 Up 0.37432773 Fzr1 fizzy/cell division cycle 20 related 1 (Drosophila) "K03364|1|0.0|1002|mmu:56371|cell division cycle 20-like protein 1, cofactor of APC complex" GO:0000152//nuclear ubiquitin ligase complex;GO:0005635//nuclear envelope - GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0008283//cell proliferation;GO:0002088//lens development in camera-type eye;GO:0006259//DNA metabolic process;GO:0000077//DNA damage checkpoint;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0007126//meiotic nuclear division;GO:0000087//mitotic M phase;GO:0048523//negative regulation of cellular process;GO:0009896 gi|9789959|ref|NP_062731.1|/0/fizzy-related protein homolog [Mus musculus] 28088 1979 43.00333333 48.40333333 0.170657911 Up 0.374196096 Rtcb "RNA 2',3'-cyclic phosphate and 5'-OH ligase" K14415|1|0.0|1023|mmu:28088|tRNA-splicing ligase RtcB [EC:6.5.1.3] - - - - 59010 1676 26.82 30.37666667 0.17965433 Up 0.374083268 Sqrdl sulfide quinone reductase-like (yeast) K17218|1|0.0|917|mmu:59010|sulfide:quinone oxidoreductase [EC:1.8.5.4] GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0044710;GO:0044710;GO:0044710 "gi|148696168|gb|EDL28115.1|/0/sulfide quinone reductase-like (yeast), isoform CRA_c, partial [Mus musculus]" 28200 1352.04 43.33 48.70666667 0.168753016 Up 0.374073865 Dhrs4 dehydrogenase/reductase (SDR family) member 4 K11147|1|6e-87|323|mmu:28200|dehydrogenase/reductase SDR family member 4 [EC:1.1.-.-] GO:0044439;GO:0044439 "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0005515//protein binding;GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0005515//protein binding;GO:0016651//oxidoreductase activity, acting on NAD(P)H" GO:0051259//protein oligomerization;GO:0001523//retinoid metabolic process;GO:0044281//small molecule metabolic process;GO:0051259//protein oligomerization;GO:0001523//retinoid metabolic process;GO:0044281//small molecule metabolic process gi|256220343|ref|NP_001033027.2|/9.03392e-146/dehydrogenase/reductase SDR family member 4 isoform 1 [Mus musculus] 17355 8337.95 10.15 8.643333333 -0.231820022 Down 0.374064463 Aff1 "AF4/FMR2 family, member 1" K15184|1|0.0|1660|mmu:17355|AF4/FMR2 family member 1 - - - - 21825 5865 2.39 1.733333333 -0.463461496 Down 0.373951634 Thbs1 thrombospondin 1 K16857|1|0.0|2345|cge:100760878|thrombospondin 1 - - - - 14251 1694 124.1133333 138.3166667 0.156316896 Up 0.373885817 Flot1 flotillin 1 K07192|1|0.0|654|cge:100763504|flotillin GO:0043234//protein complex;GO:0005901//caveola;GO:0005813//centrosome;GO:0048770 GO:0035254//glutamate receptor binding GO:0016192//vesicle-mediated transport;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007009//plasma membrane organization;GO:0006935//chemotaxis;GO:0007266//Rho protein signal transduction gi|6679809|ref|NP_032053.1|/0/flotillin-1 [Mus musculus] 22185 2194.04 41.10333333 46.4 0.174869409 Up 0.373791794 U2af2 U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 K12837|1|0.0|766|pale:102883837|splicing factor U2AF 65 kDa subunit GO:0016604//nuclear body;GO:0030529//intracellular ribonucleoprotein complex;GO:0016604//nuclear body;GO:0030529//intracellular ribonucleoprotein complex GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0036094//small molecule binding "GO:0000398//mRNA splicing, via spliceosome;GO:0006405//RNA export from nucleus;GO:0006366//transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0006405//RNA export from nucleus;GO:0006366//transcription from RNA polymerase II promoter" gi|1334149|emb|CAA45875.1|/0/unnamed protein product [Mus musculus] 72296 1956.65 14.70666667 16.90666667 0.201121955 Up 0.373725977 Rusc1 RUN and SH3 domain containing 1 - GO:0005768//endosome;GO:0031982//vesicle;GO:0097060//synaptic membrane;GO:0015630//microtubule cytoskeleton;GO:0005768//endosome;GO:0031982//vesicle;GO:0097060//synaptic membrane;GO:0015630//microtubule cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding - gi|139947575|ref|NP_001077276.1|/0/RUN and SH3 domain-containing protein 1 isoform 2 [Mus musculus] 18132 6604 21.59 18.92333333 -0.190197002 Down 0.37369777 Notch4 notch 4 K02599|1|0.0|3877|mmu:18132|Notch GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding "GO:0001885//endothelial cell development;GO:0030857//negative regulation of epithelial cell differentiation;GO:0048732//gland development;GO:0007166//cell surface receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis" gi|114326469|ref|NP_035059.2|/0/neurogenic locus notch homolog protein 4 precursor [Mus musculus] 50721 1701.05 6.623333333 5.496666667 -0.269000474 Down 0.373631953 Sirt6 sirtuin 6 K11416|1|0.0|686|mmu:50721|mono-ADP-ribosyltransferase sirtuin 6 [EC:2.4.2.31] "GO:0000784//nuclear chromosome, telomeric region;GO:0000784//nuclear chromosome, telomeric region" "GO:0046914//transition metal ion binding;GO:0043168//anion binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0016763//transferase activity, transferring pentosyl groups;GO:0046914//transition metal ion binding;GO:0043168//anion binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0016763//transferase activity, transferring pentosyl groups" GO:0000018//regulation of DNA recombination;GO:0016575//histone deacetylation;GO:0006486//protein glycosylation;GO:0000018//regulation of DNA recombination;GO:0016575//histone deacetylation;GO:0006486//protein glycosylation gi|568968007|ref|XP_006513924.1|/0/PREDICTED: NAD-dependent protein deacetylase sirtuin-6 isoform X1 [Mus musculus] 63959 2043.46 26.94 30.44666667 0.176534438 Up 0.373631953 Slc29a1 "solute carrier family 29 (nucleoside transporters), member 1" "K15014|1|0.0|874|mmu:63959|solute carrier family 29 (equilibrative nucleoside transporter), member 1/2/3" GO:0016021//integral component of membrane;GO:0044459;GO:0016021//integral component of membrane;GO:0044459;GO:0016021//integral component of membrane;GO:0044459;GO:0016021//integral component of membrane;GO:0044459;GO:0016021//integral component of membrane;GO:0044459 GO:0015932//nucleobase-containing compound transmembrane transporter activity;GO:0015932//nucleobase-containing compound transmembrane transporter activity;GO:0015932//nucleobase-containing compound transmembrane transporter activity;GO:0015932//nucleobase-containing compound transmembrane transporter activity;GO:0015932//nucleobase-containing compound transmembrane transporter activity GO:0001666//response to hypoxia;GO:0015864//pyrimidine nucleoside transport;GO:0051899//membrane depolarization;GO:0001678//cellular glucose homeostasis;GO:0007589//body fluid secretion;GO:0001666//response to hypoxia;GO:0015864//pyrimidine nucleoside transport;GO:0051899//membrane depolarization;GO:0001678//cellular glucose homeostasis;GO:0007589//body fluid secretion;GO:0001666//response to hypoxia;GO:0015864//pyrimidine nucleoside transport;GO:0051899//membrane depolarization;GO:0001678//cellular glucose homeostasis;GO:0007589//body fluid secretion;GO:0001666//response to hypoxia;GO:0015864//pyrimidine nucleoside transport;GO:0051899//membrane depolarization;GO:0001678//cellular glucose homeostasis;GO:0007589//body fluid secretion;GO:0006725//cellular aromatic compound metabolic process;GO:0001666//response to hypoxia;GO:0015864//pyrimidine nucleoside transport;GO:0051899//membrane depolarization;GO:0001678//cellular glucose homeostasis;GO:0007589//body fluid secretion gi|12584968|ref|NP_075018.1|/0/equilibrative nucleoside transporter 1 isoform 2 [Mus musculus] 70380 2251.41 12.28333333 14.17 0.20613764 Up 0.373594344 Mospd1 motile sperm domain containing 1 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter gi|21312580|ref|NP_081685.1|/8.91925e-107/motile sperm domain-containing protein 1 isoform 1 [Mus musculus] 230734 1558 9.886666667 11.53666667 0.222670344 Up 0.373584941 Yrdc yrdC domain containing (E.coli) - - GO:0005488//binding GO:0006810//transport "gi|247494089|ref|NP_705794.2|/9.8251e-104/yrdC domain-containing protein, mitochondrial precursor [Mus musculus]" 18752 2978 2.566666667 1.886666667 -0.444056393 Down 0.373556734 Prkcg "protein kinase C, gamma" K19663|1|0.0|1219|rno:24681|classical protein kinase C gamma type [EC:2.7.11.13] GO:0043005//neuron projection;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043005//neuron projection;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0032550;GO:0004697//protein kinase C activity;GO:0046914//transition metal ion binding;GO:0032550;GO:0004697//protein kinase C activity GO:0007599//hemostasis;GO:0007267//cell-cell signaling;GO:0038127//ERBB signaling pathway;GO:0033555//multicellular organismal response to stress;GO:0043066//negative regulation of apoptotic process;GO:0014072//response to isoquinoline alkaloid;GO:0009895;GO:0010863//positive regulation of phospholipase C activity;GO:0006468//protein phosphorylation;GO:0016567//protein ubiquitination;GO:0021675//nerve development;GO:0001775//cell activation;GO:0006298//mismatch repair;GO:0044708//single-organism behavior;GO:0007267//cell-cell signaling;GO:0033555//multicellular organismal response to stress;GO:0043066//negative regulation of apoptotic process;GO:0014072//response to isoquinoline alkaloid;GO:0009895;GO:0006468//protein phosphorylation;GO:0016567//protein ubiquitination;GO:0007165//signal transduction;GO:0021675//nerve development;GO:0006298//mismatch repair;GO:0044708//single-organism behavior gi|6755080|ref|NP_035232.1|/0/protein kinase C gamma type isoform 1 [Mus musculus] 545428 6329 10.34333333 8.84 -0.226582921 Down 0.373547332 Ccdc141 coiled-coil domain containing 141 K12567|1|9e-73|279|sko:100367544|titin [EC:2.7.11.1] - - - gi|299829227|ref|NP_001020747.2|/0/coiled-coil domain-containing protein 141 [Mus musculus] 69900 3172 8.516666667 10.01333333 0.233561522 Up 0.373547332 Mfsd11 major facilitator superfamily domain containing 11 K16600|1|9e-12|75.5|gga:421566|tubulin polyglutamylase TTLL2 [EC:6.-.-.-] - - - - 231821 2418 1.676666667 1.113333333 -0.590710297 Down 0.373396893 Adap1 ArfGAP with dual PH domains 1 "K12491|1|1e-22|110|api:100169536|Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3;K12489|2|1e-20|104|tad:TRIADDRAFT_57442|Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein;K12486|3|2e-20|103|hro:HELRODRAFT_75346|stromal membrane-associated protein" GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0043168//anion binding;GO:0008289//lipid binding GO:0032012//regulation of ARF protein signal transduction;GO:0019932//second-messenger-mediated signaling gi|148368976|ref|NP_766311.2|/0/arf-GAP with dual PH domain-containing protein 1 [Mus musculus] 66336 1054 1.24 1.823333333 0.556238212 Up 0.373378089 Cenpp centromere protein P K11508|1|1e-150|534|mmu:66336|centromere protein P GO:0043231//intracellular membrane-bounded organelle;GO:0043232 - - gi|12839220|dbj|BAB24472.1|/6.75763e-153/unnamed protein product [Mus musculus] 71947 4996 46.09333333 40.90666667 -0.172222121 Down 0.373274662 Tmem94 transmembrane protein 94 - GO:0031224//intrinsic component of membrane - - gi|28972091|dbj|BAC65499.1|/0/mKIAA0195 protein [Mus musculus] 67198 3903.34 1.623333333 2.266666667 0.481612974 Up 0.373208846 Spats2l "spermatogenesis associated, serine-rich 2-like" - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - "gi|148667641|gb|EDL00058.1|/0/RIKEN cDNA 2810022L02, isoform CRA_c, partial [Mus musculus]" 12843 5222 30.09333333 26.63333333 -0.176210915 Down 0.373086615 Col1a2 "collagen, type I, alpha 2" "K06236|1|0.0|793|mmu:12843|collagen, type I, alpha" - - - - 14584 2986 8.676666667 10.17 0.229106868 Up 0.372992591 Gfpt2 glutamine fructose-6-phosphate transaminase 2 K00820|1|0.0|1349|mmu:14584|glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16] GO:0044444//cytoplasmic part GO:0005488//binding;GO:0070548 GO:0009064//glutamine family amino acid metabolic process;GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0015980//energy derivation by oxidation of organic compounds;GO:0006487//protein N-linked glycosylation gi|7305087|ref|NP_038557.1|/0/glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 [Mus musculus] 407790 986 25.59666667 29.04333333 0.182251095 Up 0.372964384 Ndufa4l2 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2" K03948|1|4e-46|187|mmu:407790|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4 - - - gi|635066306|ref|XP_008001948.1|/1.05524e-45/PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 [Chlorocebus sabaeus] 16779 5624 120.16 107.5433333 -0.160038624 Down 0.372954981 Lamb2 "laminin, beta 2" "K06243|1|0.0|3619|mmu:16779|laminin, beta 2" GO:0043256//laminin complex GO:0005102//receptor binding GO:0048675//axon extension;GO:0043010//camera-type eye development;GO:0048741//skeletal muscle fiber development;GO:0022610;GO:0014037//Schwann cell differentiation;GO:0050953//sensory perception of light stimulus;GO:0006935//chemotaxis;GO:0072015//glomerular visceral epithelial cell development;GO:0021782//glial cell development;GO:0032836//glomerular basement membrane development gi|31982223|ref|NP_032509.2|/0/laminin subunit beta-2 precursor [Mus musculus] 12703 1220 0.453333333 0.89 0.97323309 Up 0.372926774 Socs1 suppressor of cytokine signaling 1 K04694|1|5e-92|340|rno:252971|suppressor of cytokine signaling 1 GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0044444//cytoplasmic part GO:0005102//receptor binding;GO:0019887//protein kinase regulator activity;GO:0004857//enzyme inhibitor activity;GO:0019900//kinase binding;GO:0005102//receptor binding;GO:0019887//protein kinase regulator activity;GO:0004857//enzyme inhibitor activity;GO:0019900//kinase binding GO:0008286//insulin receptor signaling pathway;GO:0040007//growth;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0043627//response to estrogen;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0001933//negative regulation of protein phosphorylation;GO:0044092//negative regulation of molecular function;GO:0043200//response to amino acid;GO:0009887//organ morphogenesis;GO:0030154//cell differentiation;GO:0032446//protein modification by small protein conjugation;GO:0002237//response to molecule of bacterial origin;GO:0008286//insulin receptor signaling pathway;GO:0040007//growth;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0043627//response to estrogen;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0001933//negative regulation of protein phosphorylation;GO:0044092//negative regulation of molecular function;GO:0043200//response to amino acid;GO:0009887//organ morphogenesis;GO:0030154//cell differentiation;GO:0032446//protein modification by small protein conjugation;GO:0002237//response to molecule of bacterial origin gi|594190835|ref|NP_665886.2|/4.54928e-91/suppressor of cytokine signaling 1 [Rattus norvegicus] 76522 768 6.653333333 7.91 0.24960038 Up 0.372926774 Lsm8 "LSM8 homolog, U6 small nuclear RNA associated" K12627|1|1e-49|198|aml:100479478|U6 snRNA-associated Sm-like protein LSm8 - - - - 101602 1918 0.986666667 1.526666667 0.629750422 Up 0.37283275 AI467606 expressed sequence AI467606 - GO:0031224//intrinsic component of membrane - - gi|30725748|ref|NP_849232.1|/1.0871e-110/transmembrane protein C16orf54 homolog [Mus musculus] 66653 1383 5.06 6.126666667 0.275964976 Up 0.372795141 Brf2 "BRF2, RNA polymerase III transcription initiation factor 50kDa subunit" K15197|1|0.0|779|mmu:66653|transcription factor IIIB 50 kDa subunit - - - - 353287 1836 0.726666667 0.33 -1.138827705 Down 0.372795141 Clec18a "C-type lectin domain family 18, member A" K19919|1|2e-21|107|spu:764722|cysteine-rich secretory protein;K10401|2|4e-21|105|spu:574641|kinesin family member 18/19;K20412|4|8e-21|104|mdo:100029246|peptidase inhibitor 16 - GO:0005488//binding - gi|755526932|ref|XP_006531206.2|/0/PREDICTED: C-type lectin domain family 18 member A isoform X2 [Mus musculus] 208650 6323 4.26 3.38 -0.333830184 Down 0.372785738 Cblb Casitas B-lineage lymphoma b K04707|1|0.0|1688|mmu:208650|E3 ubiquitin-protein ligase CBL [EC:2.3.2.27] GO:0031981//nuclear lumen;GO:0044425 GO:0046914//transition metal ion binding;GO:0060089;GO:0019787//ubiquitin-like protein transferase activity;GO:0019900//kinase binding;GO:0045309//protein phosphorylated amino acid binding GO:0002666//positive regulation of T cell tolerance induction;GO:0042130//negative regulation of T cell proliferation;GO:0050852//T cell receptor signaling pathway;GO:0009628//response to abiotic stimulus;GO:0032446//protein modification by small protein conjugation;GO:0009719;GO:0009896 gi|118344448|ref|NP_001028410.1|/0/E3 ubiquitin-protein ligase CBL-B [Mus musculus] 26442 1217 26.36666667 29.79666667 0.176435752 Up 0.372748129 Psma5 "proteasome (prosome, macropain) subunit, alpha type 5" K02729|1|1e-131|472|pale:102891315|20S proteasome subunit alpha 5 [EC:3.4.25.1] GO:0031981//nuclear lumen;GO:0005839//proteasome core complex;GO:0044444//cytoplasmic part GO:0004175//endopeptidase activity;GO:0005488//binding "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0006915//apoptotic process;GO:0044764;GO:0051320;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|731270096|ref|XP_010604271.1|/1.02889e-131/PREDICTED: proteasome subunit alpha type-5 [Fukomys damarensis] 381236 2854 4.056666667 3.21 -0.337721465 Down 0.372748129 Lipo1 "lipase, member O3" K14452|1|3e-156|555|cge:100757425|gastric triacylglycerol lipase [EC:3.1.1.3] - GO:0016787//hydrolase activity GO:0006629//lipid metabolic process gi|110625662|ref|NP_001013792.2|/0/lipase family member precursor [Mus musculus] 380753 1883.94 10.15 11.78333333 0.215267987 Up 0.372710519 Atxn7l1 ataxin 7-like 1 K11318|1|1e-80|303|mmu:380753|ataxin-7 - - - gi|568977831|ref|XP_006515191.1|/0/PREDICTED: ataxin-7-like protein 1 isoform X5 [Mus musculus] 73998 4742 8.77 7.406666667 -0.243752432 Down 0.372691715 Herc3 hect domain and RLD 3 K10614|1|0.0|2071|mmu:73998|E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26] - - - gi|188035869|ref|NP_082981.3|/0/probable E3 ubiquitin-protein ligase HERC3 [Mus musculus] 329828 4192 5.96 7.126666667 0.257915117 Up 0.372400241 AI464131 expressed sequence AI464131 "K01187|1|2e-97|360|dme:Dmel_CG11909|alpha-glucosidase [EC:3.2.1.20];K18412|2|4e-25|120|aqu:100636235|trinucleotide repeat-containing gene 6 protein;K12316|3|2e-22|111|mze:101467306|lysosomal alpha-glucosidase [EC:3.2.1.20];K05546|5|2e-20|104|nvi:100121937|alpha 1,3-glucosidase [EC:3.2.1.84]" GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope "GO:0005488//binding;GO:0016798//hydrolase activity, acting on glycosyl bonds" GO:0044238//primary metabolic process;GO:0007519//skeletal muscle tissue development gi|50510819|dbj|BAD32395.1|/0/mKIAA1161 protein [Mus musculus] 217325 3557 5.826666667 6.996666667 0.263996982 Up 0.372400241 Llgl2 lethal giant larvae homolog 2 (Drosophila) K06094|1|0.0|1972|mmu:217325|lethal(2) giant larvae protein GO:0044424;GO:0043227//membrane-bounded organelle;GO:0044424;GO:0043227//membrane-bounded organelle GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding GO:0007163//establishment or maintenance of cell polarity;GO:0007163//establishment or maintenance of cell polarity gi|357527422|ref|NP_001239461.1|/0/lethal(2) giant larvae protein homolog 2 isoform 2 [Mus musculus] 17909 8098 10.18666667 8.71 -0.225937419 Down 0.372400241 Myo10 myosin X K12559|1|0.0|3791|mmu:17909|myosin X GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0015629//actin cytoskeleton;GO:0030175//filopodium;GO:0044297//cell body;GO:0031252//cell leading edge;GO:0044444//cytoplasmic part "GO:0032550;GO:0000146//microfilament motor activity;GO:0003779//actin binding;GO:0043168//anion binding;GO:0008289//lipid binding;GO:0042623//ATPase activity, coupled" GO:0046847//filopodium assembly;GO:0022604//regulation of cell morphogenesis;GO:0006928//movement of cell or subcellular component;GO:0016337//single organismal cell-cell adhesion;GO:0044765//single-organism transport;GO:0006935//chemotaxis gi|130507685|ref|NP_062345.2|/0/unconventional myosin-X [Mus musculus] 231659 8546 13.71333333 11.86 -0.209475283 Down 0.372372034 Gcn1l1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) "K19759|1|7e-07|60.8|crg:105339120|dynein assembly factor 5, axonemal" - - - gi|112807186|ref|NP_766307.2|/0/eIF-2-alpha kinase activator GCN1 [Mus musculus] 76959 1372 18.13666667 20.72333333 0.19234675 Up 0.372334424 Chmp5 charged multivesicular body protein 5 K12198|1|2e-87|325|oas:101104370|charged multivesicular body protein 5 GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - GO:0007041//lysosomal transport;GO:0045184//establishment of protein localization;GO:0007033//vacuole organization gi|640833971|ref|XP_008072674.1|/7.04644e-87/PREDICTED: charged multivesicular body protein 5 isoform X1 [Tarsius syrichta] 53619 2099 25.32333333 28.71666667 0.181420975 Up 0.3722404 Blcap bladder cancer associated protein - - - - - 11898 1631 3.883333333 4.823333333 0.312734967 Up 0.372230998 Ass1 argininosuccinate synthetase 1 K01940|1|0.0|810|mmu:11898|argininosuccinate synthase [EC:6.3.4.5] GO:0043005//neuron projection;GO:0000323//lytic vacuole;GO:0031966//mitochondrial membrane;GO:0043025//neuronal cell body "GO:0032550;GO:0016879//ligase activity, forming carbon-nitrogen bonds" GO:0014075//response to amine;GO:0032496//response to lipopolysaccharide;GO:0060538//skeletal muscle organ development;GO:0006575//cellular modified amino acid metabolic process;GO:0002526//acute inflammatory response;GO:0071385//cellular response to glucocorticoid stimulus;GO:0033762//response to glucagon;GO:0009636//response to toxic substance;GO:0043627//response to estrogen;GO:0034612//response to tumor necrosis factor;GO:0010038//response to metal ion;GO:0006525//arginine metabolic process;GO:0019627//urea metabolic process;GO:0043200//response to amino acid;GO:0048565//digestive tract development;GO:0051591//response to cAMP;GO:0034341//response to interferon-gamma;GO:0034201//response to oleic acid;GO:0060359//response to ammonium ion;GO:0031667//response to nutrient levels gi|6996911|ref|NP_031520.1|/0/argininosuccinate synthase [Mus musculus] 208846 5924.28 7.83 6.576666667 -0.251655757 Down 0.37208056 Daam1 dishevelled associated activator of morphogenesis 1 K04512|1|0.0|956|myd:102755756|dishevelled associated activator of morphogenesis GO:0032432//actin filament bundle;GO:0032432//actin filament bundle;GO:0032432//actin filament bundle GO:0017016//Ras GTPase binding;GO:0008092//cytoskeletal protein binding;GO:0017016//Ras GTPase binding;GO:0008092//cytoskeletal protein binding;GO:0017016//Ras GTPase binding;GO:0008092//cytoskeletal protein binding GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization gi|37360034|dbj|BAC97995.1|/0/mKIAA0666 protein [Mus musculus] 71843 1841.76 11.75 13.59 0.209884699 Up 0.372061755 R3hcc1 R3H domain and coiled-coil containing 1 - - GO:0097159//organic cyclic compound binding;GO:0097159//organic cyclic compound binding;GO:0097159//organic cyclic compound binding - "gi|148703993|gb|EDL35940.1|/0/mCG141018, isoform CRA_b, partial [Mus musculus]" 13003 7703.35 1.843333333 1.263333333 -0.545081632 Down 0.371967731 Vcan versican K06793|1|0.0|5341|rno:114122|versican core protein GO:0031012//extracellular matrix;GO:0044421;GO:0031012//extracellular matrix;GO:0044421;GO:0005764//lysosome;GO:0031012//extracellular matrix;GO:0044431//Golgi apparatus part;GO:0044421;GO:0044431//Golgi apparatus part;GO:0005764//lysosome;GO:0044421;GO:0031012//extracellular matrix;GO:0044421;GO:0031012//extracellular matrix GO:0071813//lipoprotein particle binding;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0071813//lipoprotein particle binding;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0097367//carbohydrate derivative binding;GO:0046872//metal ion binding;GO:0071813//lipoprotein particle binding;GO:0005539//glycosaminoglycan binding;GO:0005488//binding GO:0016477//cell migration;GO:0022610;GO:0007409//axonogenesis;GO:0006950//response to stress;GO:0016477//cell migration;GO:0022610;GO:0007409//axonogenesis;GO:0006950//response to stress;GO:0016477//cell migration;GO:0006024//glycosaminoglycan biosynthetic process;GO:0044238//primary metabolic process;GO:0006790//sulfur compound metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0032502//developmental process;GO:0044707;GO:0006027//glycosaminoglycan catabolic process;GO:0007409//axonogenesis;GO:0022610;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0044238//primary metabolic process;GO:0006950//response to stress;GO:0016477//cell migration;GO:0016477//cell migration;GO:0044767//single-organism developmental process "gi|148668664|gb|EDL00983.1|/0/mCG116562, isoform CRA_c, partial [Mus musculus]" 269389 1675 3.016666667 3.84 0.348151019 Up 0.371958329 Tox2 TOX high mobility group box family member 2 K18808|1|8e-22|107|bfo:BRAFLDRAFT_68489|toll-like receptor 13 - - - gi|149408148|ref|NP_001092269.1|/0/TOX high mobility group box family member 2 [Mus musculus] 227292 2790 95.06666667 106.42 0.162757828 Up 0.37188311 Ctdsp1 "CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1" K15731|1|7e-146|520|mmu:227292|carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0004722//protein serine/threonine phosphatase activity GO:0006464//cellular protein modification process;GO:0010721//negative regulation of cell development;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter gi|23346509|ref|NP_694728.1|/6.22017e-145/carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 [Mus musculus] 68114 3717 4.216666667 5.186666667 0.298704675 Up 0.371826695 Mum1 melanoma associated antigen (mutated) 1 - GO:0043231//intracellular membrane-bounded organelle GO:0003682//chromatin binding GO:0006259//DNA metabolic process;GO:0051276//chromosome organization;GO:0033554//cellular response to stress gi|50054188|ref|NP_075920.4|/0/PWWP domain-containing protein MUM1 [Mus musculus] 68472 890 9.99 11.6 0.215568222 Up 0.371798488 Tmem126b transmembrane protein 126B K18165|1|2e-125|451|mmu:68472|complex I assembly factor TMEM126B GO:0031224//intrinsic component of membrane - - "gi|58037123|ref|NP_081010.1|/1.24402e-124/complex I assembly factor TMEM126B, mitochondrial [Mus musculus]" 19656 1710.25 8.65 10.12 0.226437252 Up 0.371779683 Rbmxl1 "RNA binding motif protein, X-linked like-1" K12885|1|2e-96|355|mmu:19656|heterogeneous nuclear ribonucleoprotein G GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0044212//transcription regulatory region DNA binding;GO:0044212//transcription regulatory region DNA binding "GO:0006366//transcription from RNA polymerase II promoter;GO:0051259//protein oligomerization;GO:0000245//spliceosomal complex assembly;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0051259//protein oligomerization;GO:0000245//spliceosomal complex assembly;GO:0000380//alternative mRNA splicing, via spliceosome" "gi|392347178|ref|XP_003749751.1|/1.06382e-114/PREDICTED: RNA binding motif protein, X-linked-like-1 [Rattus norvegicus]" 102633035 1540 0.65 0.266666667 -1.285402219 Down 0.371704464 Gm28979 predicted gene 28979 - - - - gi|148689093|gb|EDL21040.1|/5.02045e-52/mCG140729 [Mus musculus] 60507 1328 5.41 6.516666667 0.268505608 Up 0.371704464 Qtrt1 queuine tRNA-ribosyltransferase 1 K00773|1|0.0|822|mmu:60507|queuine tRNA-ribosyltransferase [EC:2.4.2.29] GO:0043231//intracellular membrane-bounded organelle "GO:0043169//cation binding;GO:0016763//transferase activity, transferring pentosyl groups" GO:0006400//tRNA modification gi|158186691|ref|NP_068688.2|/0/queuine tRNA-ribosyltransferase [Mus musculus] 18782 2264 1.336666667 1.93 0.529961112 Up 0.371695062 Pla2g2d "phospholipase A2, group IID" K01047|1|1e-79|300|mmu:18782|secretory phospholipase A2 [EC:3.1.1.4] GO:0044424 GO:0046872//metal ion binding;GO:0003824//catalytic activity GO:0006796//phosphate-containing compound metabolic process;GO:0006629//lipid metabolic process gi|7242177|ref|NP_035239.1|/1.03275e-78/group IID secretory phospholipase A2 precursor [Mus musculus] 68165 782 43.84666667 39.02666667 -0.168006925 Down 0.371478807 Fdx1l ferredoxin 1-like K02516|1|1e-14|82.4|tsp:Tsp_08085|type II protein arginine methyltransferase [EC:2.1.1.320] GO:0044429 GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy "gi|90017457|ref|NP_001034913.1|/1.6243e-95/adrenodoxin-like protein, mitochondrial precursor [Mus musculus]" 93722 4534 0.76 1.26 0.72935241 Up 0.371441197 Pcdhga10 "protocadherin gamma subfamily A, 10" K16495|1|0.0|1736|mmu:93722|protocadherin gamma subfamily A GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|18087771|ref|NP_291071.1|/0/protocadherin gamma-A10 precursor [Mus musculus] 18546 669 1.22 0.726666667 -0.747515514 Down 0.371441197 Pcp4 Purkinje cell protein 4 - GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding GO:0007399//nervous system development "gi|149060243|gb|EDM10957.1|/5.38317e-32/Purkinje cell protein 4, isoform CRA_b [Rattus norvegicus]" 20296 806 0.76 1.26 0.72935241 Up 0.371441197 Ccl2 chemokine (C-C motif) ligand 2 K14624|1|1e-66|255|mmu:20296|C-C motif chemokine 2 GO:0044424;GO:0044297//cell body;GO:0044421 GO:0005539//glycosaminoglycan binding;GO:0048020//CCR chemokine receptor binding;GO:0005125//cytokine activity GO:0009636//response to toxic substance;GO:0001935//endothelial cell proliferation;GO:0070555//response to interleukin-1;GO:0006915//apoptotic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0043277//apoptotic cell clearance;GO:0001776//leukocyte homeostasis;GO:0006996//organelle organization;GO:0007268//chemical synaptic transmission;GO:0002699//positive regulation of immune effector process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0042465;GO:0034341//response to interferon-gamma;GO:0008347//glial cell migration;GO:0031960//response to corticosteroid;GO:0019221//cytokine-mediated signaling pathway;GO:0007567//parturition;GO:0010212//response to ionizing radiation;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0001101//response to acid chemical;GO:0001817//regulation of cytokine production;GO:0035747//natural killer cell chemotaxis;GO:0001525//angiogenesis;GO:0022604//regulation of cell morphogenesis;GO:0071363//cellular response to growth factor stimulus;GO:0033273//response to vitamin;GO:0042110//T cell activation;GO:0006875//cellular metal ion homeostasis;GO:0097305//response to alcohol;GO:0034612//response to tumor necrosis factor;GO:0032496//response to lipopolysaccharide;GO:0009887//organ morphogenesis;GO:0072683 gi|74142494|dbj|BAE31998.1|/8.38236e-66/unnamed protein product [Mus musculus] 69583 1679 3.15 2.41 -0.386318682 Down 0.371403588 Tnfsf13 "tumor necrosis factor (ligand) superfamily, member 13" K05475|1|7e-132|473|mmu:69583|tumor necrosis factor ligand superfamily member 13 - - - - 74335 2479 2.613333333 1.933333333 -0.434800754 Down 0.371365978 Xrcc3 X-ray repair complementing defective repair in Chinese hamster cells 3 K10880|1|0.0|652|mmu:74335|DNA-repair protein XRCC3 - - - - 84092 4177 11.3 9.7 -0.22026612 Down 0.371328369 Usp8 ubiquitin specific peptidase 8 K11839|1|0.0|1917|mmu:84092|ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12] GO:0019898//extrinsic component of membrane;GO:0030141//secretory granule;GO:0010008//endosome membrane;GO:0019898//extrinsic component of membrane;GO:0030141//secretory granule;GO:0010008//endosome membrane GO:0016790//thiolester hydrolase activity;GO:0019904//protein domain specific binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0019904//protein domain specific binding;GO:0019783//ubiquitin-like protein-specific protease activity GO:0006996//organelle organization;GO:0007264//small GTPase mediated signal transduction;GO:0019941//modification-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0006996//organelle organization;GO:0007264//small GTPase mediated signal transduction;GO:0019941//modification-dependent protein catabolic process;GO:0016579//protein deubiquitination "gi|148696217|gb|EDL28164.1|/0/ubiquitin specific peptidase 8, isoform CRA_b, partial [Mus musculus]" 73582 1439 0.623333333 1.09 0.806252366 Up 0.371177931 Camkmt calmodulin-lysine N-methyltransferase K18826|1|2e-161|571|mmu:73582|calmodulin-lysine N-methyltransferase [EC:2.1.1.60] GO:0044424 GO:0016279//protein-lysine N-methyltransferase activity GO:0008152//metabolic process gi|124249226|ref|NP_082852.1|/1.33866e-160/calmodulin-lysine N-methyltransferase [Mus musculus] 216821 1240.44 37.40333333 42.11666667 0.171224412 Up 0.370989883 Tmem11 transmembrane protein 11 - GO:0031304//intrinsic component of mitochondrial inner membrane;GO:0031988//membrane-bounded vesicle;GO:0031672//A band;GO:0031304//intrinsic component of mitochondrial inner membrane GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0016836//hydro-lyase activity GO:0006996//organelle organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0051707//response to other organism;GO:0006007//glucose catabolic process;GO:0006996//organelle organization;GO:0044710;GO:0016049//cell growth "gi|507570966|ref|XP_004669086.1|/1.10348e-96/PREDICTED: transmembrane protein 11, mitochondrial isoform X2 [Jaculus jaculus]" 16818 2074 0.093333333 0.413333333 2.146841388 Up 0.370952273 Lck lymphocyte protein tyrosine kinase K05856|1|0.0|1057|mmu:16818|lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] "GO:0044459;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005813//centrosome;GO:0044459;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005813//centrosome;GO:0044459;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005813//centrosome" GO:0004713//protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004713//protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004713//protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0004721//phosphoprotein phosphatase activity GO:0010467//gene expression;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0006915//apoptotic process;GO:0012502//induction of programmed cell death;GO:0009605//response to external stimulus;GO:0000302//response to reactive oxygen species;GO:0042492//gamma-delta T cell differentiation;GO:0010038//response to metal ion;GO:0051283//negative regulation of sequestering of calcium ion;GO:0050852//T cell receptor signaling pathway;GO:0045987//positive regulation of smooth muscle contraction;GO:0010467//gene expression;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0006915//apoptotic process;GO:0012502//induction of programmed cell death;GO:0009605//response to external stimulus;GO:0000302//response to reactive oxygen species;GO:0042492//gamma-delta T cell differentiation;GO:0010038//response to metal ion;GO:0051283//negative regulation of sequestering of calcium ion;GO:0050852//T cell receptor signaling pathway;GO:0045987//positive regulation of smooth muscle contraction;GO:0010467//gene expression;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0006915//apoptotic process;GO:0012502//induction of programmed cell death;GO:0009605//response to external stimulus;GO:0000302//response to reactive oxygen species;GO:0042492//gamma-delta T cell differentiation;GO:0010038//response to metal ion;GO:0051283//negative regulation of sequestering of calcium ion;GO:0050852//T cell receptor signaling pathway;GO:0045987//positive regulation of smooth muscle contraction gi|244791455|ref|NP_001155904.1|/0/proto-oncogene tyrosine-protein kinase LCK isoform a [Mus musculus] 14957 776 0.093333333 0.41 2.135159583 Up 0.370877054 Hist1h1d "histone cluster 1, H1d" K11275|1|4e-22|107|pale:102898872|histone H1/5 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0034728//nucleosome organization gi|355561389|gb|EHH18021.1|/3.40114e-21/histone H1b [Macaca mulatta] 29865 1745 0.773333333 1.27 0.715666192 Up 0.370867652 Cabp5 calcium binding protein 5 K02183|1|2e-28|129|crg:105340108|calmodulin GO:0044444//cytoplasmic part GO:0043169//cation binding - gi|7304943|ref|NP_038905.1|/2.9138e-91/calcium-binding protein 5 [Mus musculus] 66912 1889 87.98333333 98.32 0.160254656 Up 0.37085825 Bzw2 basic leucine zipper and W2 domains 2 K03260|1|2e-06|57.0|hmg:101237497|translation initiation factor 4G;K03240|2|2e-06|57.0|xtr:100487780|translation initiation factor eIF-2B subunit epsilon - - GO:0048731//system development;GO:0048869//cellular developmental process;GO:0044260 gi|966933605|ref|XP_001104484.3|/0/PREDICTED: basic leucine zipper and W2 domain-containing protein 2 isoform X1 [Macaca mulatta] 214469 5053.91 13.49 11.67666667 -0.208261861 Down 0.370811238 Fam168b "family with sequence similarity 168, member B" K03006|1|7e-06|56.6|crg:105344236|DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] GO:0042995//cell projection;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0044424;GO:0042995//cell projection;GO:0016020//membrane;GO:0005737//cytoplasm - - gi|60360118|dbj|BAD90278.1|/5.49823e-97/mKIAA4042 protein [Mus musculus] 108083 5068 9.993333333 8.54 -0.226729908 Down 0.370773628 Pip4k2b "phosphatidylinositol-5-phosphate 4-kinase, type II, beta" K00920|1|0.0|759|ngi:103743802|1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane GO:0032550;GO:0004871//signal transducer activity;GO:0016307//phosphatidylinositol phosphate kinase activity GO:0046488//phosphatidylinositol metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0007165//signal transduction gi|589917222|ref|XP_006971925.1|/0/PREDICTED: phosphatidylinositol 5-phosphate 4-kinase type-2 beta [Peromyscus maniculatus bairdii] 79196 3819.2 5.813333333 6.96 0.259721672 Up 0.370726616 Osbpl5 oxysterol binding protein-like 5 K20464|1|0.0|1697|mmu:79196|oxysterol-binding protein-related protein 5/8 GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0032934//sterol binding;GO:0032934//sterol binding GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0010876//lipid localization;GO:0051234//establishment of localization gi|15011889|ref|NP_077251.1|/0/oxysterol-binding protein-related protein 5 isoform 1 [Mus musculus] 66840 2344 18.11333333 20.61 0.18629244 Up 0.370717214 Wdr45b WD repeat domain 45B K14810|1|1e-56|223|tsp:Tsp_06600|ATP-dependent RNA helicase DDX56/DBP9 [EC:3.6.4.13];K17908|2|7e-32|141|cfo:105254477|autophagy-related protein 18 - - - gi|27229002|ref|NP_080069.2|/0/WD repeat domain phosphoinositide-interacting protein 3 [Mus musculus] 319153 483 0.193333333 0.556666667 1.525723297 Up 0.370707812 Hist1h3i "histone cluster 1, H3i" K11253|1|2e-71|269|rno:680498|histone H3 - - - gi|829934773|ref|XP_012596746.1|/2.97601e-71/PREDICTED: uncharacterized protein LOC105858277 [Microcebus murinus] 20821 2790 2.8 3.586666667 0.357216845 Up 0.370651397 Trim21 tripartite motif-containing 21 K10651|1|0.0|916|mmu:20821|tripartite motif-containing protein 21 [EC:2.3.2.27] GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0031400;GO:0051259//protein oligomerization;GO:0051726//regulation of cell cycle;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0031647//regulation of protein stability;GO:0016567//protein ubiquitination;GO:0031400;GO:0051259//protein oligomerization;GO:0051726//regulation of cell cycle;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0031647//regulation of protein stability;GO:0016567//protein ubiquitination gi|14714855|gb|AAH10580.1|/0/Tripartite motif-containing 21 [Mus musculus] 24044 2370 14.02 16.11 0.200470145 Up 0.370613788 Scamp2 secretory carrier membrane protein 2 K19995|1|7e-153|543|mmu:24044|secretory carrier-associated membrane protein "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031224//intrinsic component of membrane;GO:0010008//endosome membrane;GO:0005802//trans-Golgi network;GO:0031981//nuclear lumen" GO:0022892//substrate-specific transporter activity GO:0016192//vesicle-mediated transport;GO:0015031//protein transport gi|12331398|ref|NP_073724.1|/5.67375e-152/secretory carrier-associated membrane protein 2 [Mus musculus] 110173 3688 4.543333333 5.543333333 0.287002606 Up 0.370576178 Manba "mannosidase, beta A, lysosomal" K01192|1|0.0|1801|mmu:110173|beta-mannosidase [EC:3.2.1.25] GO:0000323//lytic vacuole GO:0048029//monosaccharide binding;GO:0015923//mannosidase activity GO:0009100//glycoprotein metabolic process gi|158533990|ref|NP_081564.3|/0/beta-mannosidase precursor [Mus musculus] 17886 7439 41.36 36.73333333 -0.171146368 Down 0.370576178 Myh9 "myosin, heavy polypeptide 9, non-muscle" K10352|1|0.0|3209|mmu:17886|myosin heavy chain GO:0030139//endocytic vesicle;GO:0031254//cell trailing edge;GO:0031252//cell leading edge;GO:0032432//actin filament bundle;GO:0032155;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0045202//synapse;GO:0016459//myosin complex;GO:0015630//microtubule cytoskeleton GO:0019900//kinase binding;GO:0008556//potassium-transporting ATPase activity;GO:0032550;GO:0042802//identical protein binding;GO:0001664//G-protein coupled receptor binding;GO:0003774//motor activity;GO:0003779//actin binding GO:0043009//chordate embryonic development;GO:0007051//spindle organization;GO:0010522//regulation of calcium ion transport into cytosol;GO:0007127//meiosis I;GO:0009154//purine ribonucleotide catabolic process;GO:0043542//endothelial cell migration;GO:0001767;GO:0045184//establishment of protein localization;GO:0000768//syncytium formation by plasma membrane fusion;GO:0033619//membrane protein proteolysis;GO:0007155//cell adhesion;GO:0022604//regulation of cell morphogenesis;GO:0002573//myeloid leukocyte differentiation;GO:0030036//actin cytoskeleton organization;GO:0030030//cell projection organization;GO:0006909//phagocytosis gi|74180977|dbj|BAE27768.1|/0/unnamed protein product [Mus musculus] 21429 4611.87 20.12 17.63 -0.19059783 Down 0.370529166 Ubtf "upstream binding transcription factor, RNA polymerase I" K09273|1|0.0|1190|mmu:21429|upstream-binding transcription factor GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0006360//transcription from RNA polymerase I promoter;GO:0006342//chromatin silencing;GO:0001824//blastocyst development;GO:0006360//transcription from RNA polymerase I promoter;GO:0001824//blastocyst development;GO:0006360//transcription from RNA polymerase I promoter;GO:0001824//blastocyst development;GO:0006360//transcription from RNA polymerase I promoter;GO:0001824//blastocyst development gi|189095262|ref|NP_001121162.1|/0/nucleolar transcription factor 1 isoform 2 [Rattus norvegicus] 63955 3343 2.253333333 2.97 0.398402185 Up 0.370482154 Cables1 CDK5 and Abl enzyme substrate 1 K09528|1|1e-21|108|cbr:CBG04113|DnaJ homolog subfamily C member 8 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0019887//protein kinase regulator activity;GO:0005488//binding;GO:0019887//protein kinase regulator activity;GO:0005488//binding GO:0048731//system development;GO:0007049//cell cycle;GO:0050794//regulation of cellular process;GO:0048731//system development;GO:0007049//cell cycle;GO:0050794//regulation of cellular process gi|226371633|ref|NP_001139759.1|/0/CDK5 and ABL1 enzyme substrate 1 isoform 1 [Mus musculus] 73656 1714.78 7.196666667 8.513333333 0.242395282 Up 0.370406935 Ms4a6c "membrane-spanning 4-domains, subfamily A, member 6C" "K08090|1|6e-13|78.6|rno:25316|membrane-spanning 4-domains, subfamily A, member 2" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|124430755|ref|NP_082871.2|/9.72554e-101/membrane-spanning 4-domains subfamily A member 6C isoform 1 [Mus musculus] 70757 3603 2.166666667 2.873333333 0.407248151 Up 0.370397533 Hacd2 3-hydroxyacyl-CoA dehydratase 2 K10703|1|3e-126|456|mmu:70757|very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134] - - - - 22704 4637 9.443333333 11.02 0.222756123 Up 0.370359923 Zfp46 zinc finger protein 46 K09228|1|0.0|981|mmu:22704|KRAB domain-containing zinc finger protein GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|50511065|dbj|BAD32518.1|/0/mKIAA1710 protein [Mus musculus] 14544 5417 4.243333333 3.38 -0.328174767 Down 0.370341119 Gda guanine deaminase K01487|1|0.0|842|mmu:14544|guanine deaminase [EC:3.5.4.3] - "GO:0046914//transition metal ion binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines" GO:0006145//purine nucleobase catabolic process gi|50510861|dbj|BAD32416.1|/0/mKIAA1258 protein [Mus musculus] 232934 2188 2.506666667 3.253333333 0.376148486 Up 0.370322314 Mypop "Myb-related transcription factor, partner of profilin" K13814|1|4e-10|69.3|cmy:102933152|t-SNARE domain-containing protein 1;K03025|2|2e-08|63.9|lcm:102357081|DNA-directed RNA polymerase III subunit RPC6 - - - - 100302688 872 0.23 0.01 -4.523561956 Down 0.370153071 Gm17455 "predicted gene, 17455" - - - - gi|568966120|ref|XP_006513025.1|/6.98272e-56/PREDICTED: uncharacterized protein C10orf105 homolog isoform X3 [Mus musculus] 21414 2695 1.296666667 0.793333333 -0.708808582 Down 0.370115461 Tcf7 "transcription factor 7, T cell specific" K02620|1|2e-142|509|rno:363595|transcription factor 7 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0007442//hindgut morphogenesis;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0002681;GO:0050794//regulation of cellular process;GO:0035112//genitalia morphogenesis;GO:0070670//response to interleukin-4;GO:0007399//nervous system development;GO:0007442//hindgut morphogenesis;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0002681;GO:0050794//regulation of cellular process;GO:0035112//genitalia morphogenesis;GO:0070670//response to interleukin-4;GO:0007399//nervous system development gi|568972852|ref|XP_006532861.1|/0/PREDICTED: transcription factor 7 isoform X1 [Mus musculus] 22640 1851.55 5.34 6.426666667 0.267230904 Up 0.370021437 Zfp1 zinc finger protein 1 K09228|1|0.0|813|mmu:22640|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|55483|emb|CAA34510.1|/0/unnamed protein product [Mus musculus] 19659 2628 3.133333333 3.96 0.337802174 Up 0.370002633 Rbp1 "retinol binding protein 1, cellular" K06210|1|1e-73|280|mcc:715667|nicotinamide mononucleotide adenylyltransferase [EC:2.7.7.1 2.7.7.18];K14622|4|7e-45|185|ola:101166154|retinol binding protein 2 - - - gi|589924677|ref|XP_006975215.1|/6.38505e-92/PREDICTED: LOW QUALITY PROTEIN: retinol-binding protein 1 [Peromyscus maniculatus bairdii] 668039 4538 0.346666667 0.053333333 -2.700439718 Down 0.369936816 Gm14434 predicted gene 14434 K09228|1|0.0|1094|mmu:100043915|KRAB domain-containing zinc finger protein - - - "gi|150246529|ref|NP_001092819.1|/0/KRAB box and zinc finger, C2H2 type domain containing [Mus musculus]" 100043915 4538 0.346666667 0.053333333 -2.700439718 Down 0.369936816 Gm4724 predicted gene 4724 K09228|1|0.0|1094|mmu:100043915|KRAB domain-containing zinc finger protein - - - "gi|150246529|ref|NP_001092819.1|/0/KRAB box and zinc finger, C2H2 type domain containing [Mus musculus]" 100043381 4538 0.346666667 0.053333333 -2.700439718 Down 0.369936816 Gm14308 predicted gene 14308 K09228|1|0.0|1094|mmu:100043915|KRAB domain-containing zinc finger protein - - - "gi|150246529|ref|NP_001092819.1|/0/KRAB box and zinc finger, C2H2 type domain containing [Mus musculus]" 70625 3040 4.846666667 5.883333333 0.279640914 Up 0.369927414 Med26 mediator complex subunit 26 K15169|1|0.0|947|mmu:70625|mediator of RNA polymerase II transcription subunit 26 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003676//nucleic acid binding GO:0006366//transcription from RNA polymerase II promoter gi|268839392|ref|NP_081761.2|/0/mediator of RNA polymerase II transcription subunit 26 [Mus musculus] 21346 1382 92.36333333 82.89 -0.156122177 Down 0.369889804 Tagln2 transgelin 2 K20526|1|1e-112|409|mmu:21346|transgelin GO:0005635//nuclear envelope;GO:0016020//membrane GO:0005488//binding GO:0048513//animal organ development gi|30519911|ref|NP_848713.1|/1.08356e-111/transgelin-2 [Mus musculus] 71994 2003 35.38666667 39.91 0.173544409 Up 0.369880402 Cnn3 "calponin 3, acidic" "K07441|1|2e-165|585|gga:424484|beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141];K20526|2|6e-40|168|hro:HELRODRAFT_184984|transgelin;K09228|5|2e-38|163|cfa:491863|KRAB domain-containing zinc finger protein" GO:0015630//microtubule cytoskeleton;GO:0044297//cell body;GO:0015629//actin cytoskeleton;GO:0044327//dendritic spine head GO:0015631//tubulin binding GO:0043462//regulation of ATPase activity;GO:0030036//actin cytoskeleton organization gi|21312564|ref|NP_082320.1|/0/calponin-3 [Mus musculus] 52118 2902 17.39666667 19.84333333 0.189843492 Up 0.369786378 Pvr poliovirus receptor K06539|1|0.0|792|mmu:52118|poliovirus receptor GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen GO:0005515//protein binding GO:0048870//cell motility;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0007155//cell adhesion;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002420 gi|28076965|ref|NP_081790.1|/0/poliovirus receptor precursor [Mus musculus] 16521 4496 8.293333333 9.723333333 0.229498901 Up 0.369720561 Kcnj5 "potassium inwardly-rectifying channel, subfamily J, member 5" K04999|1|0.0|805|mmu:16521|potassium inwardly-rectifying channel subfamily J member 5 GO:0009986//cell surface;GO:0042383//sarcolemma;GO:0031224//intrinsic component of membrane GO:0005242//inward rectifier potassium channel activity GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|84370254|ref|NP_034735.3|/0/G protein-activated inward rectifier potassium channel 4 [Mus musculus] 219140 5868.95 4.436666667 3.556666667 -0.318950395 Down 0.369664147 Spata13 spermatogenesis associated 13 K05769|1|0.0|730|mdo:100025913|Rho guanine nucleotide exchange factor 4 - - - gi|890820458|ref|NP_001297523.1|/0/spermatogenesis-associated protein 13 isoform 2 [Mus musculus] 263803 2948 5.38 4.39 -0.293385233 Down 0.369645342 Pkn3 protein kinase N3 K06071|1|0.0|1569|mmu:263803|protein kinase N [EC:2.7.11.13] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004674//protein serine/threonine kinase activity GO:0001667//ameboidal-type cell migration;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007154//cell communication gi|24418929|ref|NP_722500.1|/0/serine/threonine-protein kinase N3 [Mus musculus] 50783 953 36.25666667 40.71 0.167136928 Up 0.36943849 Lsm4 "LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated" K12623|1|9e-45|182|cge:100769464|U6 snRNA-associated Sm-like protein LSm4 - - - - 208638 1594 9.573333333 11.13666667 0.218224234 Up 0.36943849 Slc25a38 "solute carrier family 25, member 38" "K15118|1|7e-174|612|mmu:208638|solute carrier family 25, member 38" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0030099//myeloid cell differentiation;GO:0051234//establishment of localization gi|21450145|ref|NP_659042.1|/6.02586e-173/solute carrier family 25 member 38 [Mus musculus] 16012 1305 13.84333333 15.89666667 0.199532911 Up 0.369410282 Igfbp6 insulin-like growth factor binding protein 6 K10138|1|8e-29|130|pss:102445995|insulin-like growth factor-binding protein 3 GO:0044421;GO:0043231//intracellular membrane-bounded organelle GO:0005520//insulin-like growth factor binding GO:0016049//cell growth gi|168693654|ref|NP_032370.2|/1.64448e-122/insulin-like growth factor-binding protein 6 precursor [Mus musculus] 72147 2186 3.533333333 2.753333333 -0.359850578 Down 0.369071797 Zbtb46 zinc finger and BTB domain containing 46 K10517|1|0.0|807|mmu:72147|zinc finger and BTB domain-containing protein 46 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding "GO:0045597//positive regulation of cell differentiation;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0006351//transcription, DNA-templated;GO:0045597//positive regulation of cell differentiation;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0006351//transcription, DNA-templated" gi|241896986|ref|NP_081932.1|/0/zinc finger and BTB domain-containing protein 46 isoform 1 [Mus musculus] 14459 461 0.226666667 0.01 -4.502500341 Down 0.368958968 Gast gastrin K13768|1|1e-53|209|mmu:14459|gastrin - - - - 78048 418 0.01 0.226666667 4.502500341 Up 0.368958968 4930571O06Rik RIKEN cDNA 4930571O06 gene - - - - gi|148679591|gb|EDL11538.1|/4.03871e-12/mCG1036122 [Mus musculus] 20310 1083 0.01 0.226666667 4.502500341 Up 0.368958968 Cxcl2 chemokine (C-X-C motif) ligand 2 K05505|1|1e-42|176|mmu:20310|C-X-C motif chemokine 1/2/3 GO:0044421 GO:0005125//cytokine activity GO:0006952//defense response;GO:0010212//response to ionizing radiation;GO:0008219//cell death;GO:0043627//response to estrogen;GO:0009611//response to wounding;GO:0031960//response to corticosteroid;GO:0070555//response to interleukin-1;GO:0032496//response to lipopolysaccharide;GO:0030595//leukocyte chemotaxis;GO:0051480//regulation of cytosolic calcium ion concentration gi|6677885|ref|NP_033166.1|/1.07562e-41/C-X-C motif chemokine 2 precursor [Mus musculus] 100041724 676 0.226666667 0.01 -4.502500341 Down 0.368958968 Gm15217 predicted gene 15217 - - - - - 225187 3256 1.523333333 0.993333333 -0.616881835 Down 0.368921358 Ankrd29 ankyrin repeat domain 29 K15503|1|7e-37|159|aqu:100635111|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B - - - gi|298566260|ref|NP_001177300.1|/3.67162e-160/ankyrin repeat domain-containing protein 29 [Mus musculus] 224860 4068 2.93 3.733333333 0.349563662 Up 0.368893151 Plcl2 phospholipase C-like 2 K15370|1|0.0|2155|mmu:224860|inactive phospholipase C-like protein 2 GO:0044424 GO:0060089;GO:0046872//metal ion binding;GO:0008289//lipid binding;GO:0004629//phospholipase C activity GO:0007165//signal transduction;GO:0044238//primary metabolic process gi|226342967|ref|NP_038908.2|/0/inactive phospholipase C-like protein 2 [Mus musculus] 56314 6486 2.956666667 3.756666667 0.345481506 Up 0.368893151 Zfp113 zinc finger protein 113 K09228|1|0.0|859|mmu:56314|KRAB domain-containing zinc finger protein - GO:0005515//protein binding;GO:0043169//cation binding - gi|60360620|dbj|BAD90324.1|/0/mKIAA4229 protein [Mus musculus] 78892 4184.13 16.97666667 19.38666667 0.191511552 Up 0.368883749 Crispld2 cysteine-rich secretory protein LCCL domain containing 2 K19919|1|0.0|860|cfr:102517905|cysteine-rich secretory protein "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0005539//glycosaminoglycan binding;GO:0005539//glycosaminoglycan binding GO:0043062//extracellular structure organization;GO:0030323//respiratory tube development;GO:0043062//extracellular structure organization;GO:0030323//respiratory tube development "gi|148679677|gb|EDL11624.1|/0/cysteine-rich secretory protein LCCL domain containing 2, isoform CRA_d, partial [Mus musculus]" 108673 3003 4.73 5.76 0.284228628 Up 0.368817932 Ccdc86 coiled-coil domain containing 86 K14822|1|2e-147|526|mmu:108673|rRNA-processing protein CGR1 GO:0031981//nuclear lumen - - "gi|148709450|gb|EDL41396.1|/5.55993e-147/coiled-coil domain containing 86, partial [Mus musculus]" 14538 4154.8 4.873333333 5.9 0.275806049 Up 0.368817932 Gcnt2 "glucosaminyl (N-acetyl) transferase 2, I-branching enzyme" "K00742|1|0.0|696|rno:306860|N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase [EC:2.4.1.150]" - - - "gi|39995102|ref|NP_076376.3|/0/N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase isoform B [Mus musculus]" 108705 2275 75.02333333 83.67 0.157371071 Up 0.36877092 Pttg1ip pituitary tumor-transforming 1 interacting protein K12160|1|2e-39|167|aml:100465329|small ubiquitin-related modifier GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane - GO:0006886//intracellular protein transport gi|22122339|ref|NP_666037.1|/2.17775e-60/pituitary tumor-transforming gene 1 protein-interacting protein precursor [Mus musculus] 68323 999 13.8 15.83333333 0.198296746 Up 0.368742713 Nudt22 nudix (nucleoside diphosphate linked moiety X)-type motif 22 - - GO:0003824//catalytic activity - gi|21311969|ref|NP_080951.1|/2.9407e-152/nucleoside diphosphate-linked moiety X motif 22 [Mus musculus] 21937 2186 35.05333333 39.40666667 0.168888079 Up 0.368733311 Tnfrsf1a "tumor necrosis factor receptor superfamily, member 1a" K03158|1|0.0|818|mmu:21937|tumor necrosis factor receptor superfamily member 1A GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0032991//macromolecular complex;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0044421 GO:0005035//death receptor activity;GO:0019955//cytokine binding;GO:0019899//enzyme binding "GO:0006954//inflammatory response;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0006915//apoptotic process;GO:0009612//response to mechanical stimulus;GO:0010243//response to organonitrogen compound;GO:0019221//cytokine-mediated signaling pathway;GO:0000060//protein import into nucleus, translocation;GO:0001819//positive regulation of cytokine production;GO:0006692;GO:0002237//response to molecule of bacterial origin;GO:0001101//response to acid chemical;GO:0006721//terpenoid metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0009698//phenylpropanoid metabolic process;GO:0051259//protein oligomerization;GO:0032355//response to estradiol;GO:0001818//negative regulation of cytokine production" gi|31560799|ref|NP_035739.2|/0/tumor necrosis factor receptor superfamily member 1A precursor [Mus musculus] 16782 5182 2.243333333 2.956666667 0.3983276 Up 0.368705104 Lamc2 "laminin, gamma 2" "K06246|1|0.0|2361|mmu:16782|laminin, gamma 2" GO:0044444//cytoplasmic part;GO:0043256//laminin complex GO:0005539//glycosaminoglycan binding GO:0022610 gi|110624798|ref|NP_032511.3|/0/laminin subunit gamma-2 precursor [Mus musculus] 211347 7365 2.23 2.94 0.398772445 Up 0.368705104 Pank3 pantothenate kinase 3 K09680|1|0.0|698|mcf:102123167|type II pantothenate kinase [EC:2.7.1.33] GO:0044424 GO:0032550;GO:0016301//kinase activity GO:0009108//coenzyme biosynthetic process;GO:0006796//phosphate-containing compound metabolic process gi|74200242|dbj|BAE22924.1|/0/unnamed protein product [Mus musculus] 212528 2148.05 16.81666667 19.22 0.192716568 Up 0.368695701 Trmt1 tRNA methyltransferase 1 K00555|1|0.0|1316|mmu:212528|tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216] - - - gi|74213310|dbj|BAE41778.1|/0/unnamed protein product [Mus musculus] 14912 1907 16.59666667 18.98666667 0.194093131 Up 0.368526458 Nkx6-2 NK6 homeobox 2 K09350|1|4e-143|511|rno:309095|homeobox protein Nkx-6.2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding GO:0031016//pancreas development;GO:0006366//transcription from RNA polymerase II promoter;GO:0014003//oligodendrocyte development;GO:0021520//spinal cord motor neuron cell fate specification;GO:0010453//regulation of cell fate commitment;GO:0021521//ventral spinal cord interneuron specification;GO:0050905//neuromuscular process;GO:0031016//pancreas development;GO:0006366//transcription from RNA polymerase II promoter;GO:0014003//oligodendrocyte development;GO:0021520//spinal cord motor neuron cell fate specification;GO:0010453//regulation of cell fate commitment;GO:0021521//ventral spinal cord interneuron specification;GO:0050905//neuromuscular process gi|76443675|ref|NP_899071.2|/3.10819e-142/homeobox protein Nkx-6.2 [Mus musculus] 73690 1081 2.45 3.193333333 0.382281406 Up 0.368498251 Glipr1 GLI pathogenesis-related 1 (glioma) K20412|1|3e-29|131|pss:102449937|peptidase inhibitor 16;K19919|2|2e-28|128|mdo:100015721|cysteine-rich secretory protein GO:0031224//intrinsic component of membrane - GO:0006629//lipid metabolic process gi|21312072|ref|NP_082884.1|/9.46169e-123/glioma pathogenesis-related protein 1 precursor [Mus musculus] 17912 4985.51 4.323333333 3.453333333 -0.324154477 Down 0.368441837 Myo1b myosin IB K10356|1|0.0|2052|mmu:17912|myosin I GO:0042995//cell projection;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0042995//cell projection;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0042995//cell projection;GO:0015629//actin cytoskeleton;GO:0016020//membrane GO:0008092//cytoskeletal protein binding;GO:0032550;GO:0043168//anion binding;GO:0003774//motor activity;GO:0008092//cytoskeletal protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0043168//anion binding;GO:0008092//cytoskeletal protein binding;GO:0032550;GO:0043168//anion binding;GO:0003774//motor activity GO:0048731//system development;GO:0007015//actin filament organization;GO:0006928//movement of cell or subcellular component;GO:0007015//actin filament organization;GO:0006928//movement of cell or subcellular component;GO:0007015//actin filament organization;GO:0006928//movement of cell or subcellular component gi|240120042|ref|NP_001155289.1|/0/unconventional myosin-Ib isoform 1 [Mus musculus] 15374 1384 37.83666667 33.52666667 -0.174475943 Down 0.368300801 Hn1 hematological and neurological expressed sequence 1 - - - - gi|755537448|ref|XP_011247058.1|/1.99503e-87/PREDICTED: hematological and neurological expressed 1 protein isoform X1 [Mus musculus] 242316 3532 0.376666667 0.073333333 -2.360747344 Down 0.368253789 Gdf6 growth differentiation factor 6 K20012|1|0.0|791|mmu:242316|growth differentiation factor 6 GO:0044421 GO:0005102//receptor binding;GO:0042802//identical protein binding "GO:0001934//positive regulation of protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0030182//neuron differentiation" gi|41529818|ref|NP_038554.1|/0/growth/differentiation factor 6 precursor [Mus musculus] 269704 4139 12.63666667 10.9 -0.213287821 Down 0.36821618 Zfp664 zinc finger protein 664 K09228|1|1e-98|364|oaa:100092035|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|594064744|ref|XP_006056376.1|/5.85458e-166/PREDICTED: zinc finger protein 664 isoform X1 [Bubalus bubalis] 68549 4590.99 1.246666667 1.816666667 0.54321796 Up 0.368206777 Sgol2a shugoshin-like 2a (S. pombe) K11581|1|0.0|1818|mmu:68549|shugoshin-like 2 "GO:0008278//cohesin complex;GO:0000794//condensed nuclear chromosome;GO:0000775//chromosome, centromeric region;GO:0008278//cohesin complex;GO:0000794//condensed nuclear chromosome;GO:0000775//chromosome, centromeric region" - GO:0034096//positive regulation of maintenance of meiotic sister chromatid cohesion;GO:0033036;GO:0034096//positive regulation of maintenance of meiotic sister chromatid cohesion;GO:0033036 gi|295424108|ref|NP_001171338.1|/0/shugoshin-like 2 isoform 2 [Mus musculus] 224020 6449 15.41 13.39666667 -0.201992785 Down 0.368122156 Pi4ka "phosphatidylinositol 4-kinase, catalytic, alpha polypeptide" K00888|1|0.0|3944|mmu:224020|phosphatidylinositol 4-kinase A [EC:2.7.1.67] GO:0000139//Golgi membrane "GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0046488//phosphatidylinositol metabolic process;GO:0048017//inositol lipid-mediated signaling gi|998491021|sp|E9Q3L2.2|PI4KA_MOUSE/0/RecName: Full=Phosphatidylinositol 4-kinase alpha; Short=PI4-kinase alpha; Short=PI4K-alpha; Short=PtdIns-4-kinase alpha 67843 2808.89 26.59666667 23.55 -0.175518386 Down 0.367999925 Slc35a4 "solute carrier family 35, member A4" "K15273|1|2e-133|479|mmu:67843|solute carrier family 35 (probable UDP-sugar transporter), member A4" GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane - GO:0006810//transport;GO:0006810//transport gi|134031966|ref|NP_080680.2|/2.04342e-132/probable UDP-sugar transporter protein SLC35A4 [Mus musculus] 382551 738 5.203333333 6.27 0.269029312 Up 0.367990522 Cd300lh CD300 molecule like family member D3 K20395|1|8e-97|355|mmu:382551|CO300B/D/F antigen GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part - GO:0002573//myeloid leukocyte differentiation gi|568974650|ref|XP_006533716.1|/5.8004e-96/PREDICTED: CMRF35-like molecule 3 isoform X1 [Mus musculus] 70886 2309 1.26 0.766666667 -0.716752373 Down 0.367924706 4921515E04Rik RIKEN cDNA 4921515E04 gene - - - - "gi|148676986|gb|EDL08933.1|/1.14664e-32/mCG145919, partial [Mus musculus]" 100628619 61 1.236666667 0.75 -0.721494185 Down 0.367924706 Mir5114 microRNA 5114 - - - - - 74241 3115.12 10.81 12.53666667 0.213787283 Up 0.367915303 Chpf chondroitin polymerizing factor K00747|1|0.0|1484|mmu:74241|chondroitin polymerizing factor [EC:2.4.1.175 2.4.1.226] GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane GO:0015020//glucuronosyltransferase activity;GO:0043169//cation binding;GO:0008376//acetylgalactosaminyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0043169//cation binding;GO:0008376//acetylgalactosaminyltransferase activity - gi|48526514|ref|NP_001001566.1|/0/chondroitin sulfate synthase 2 isoform a [Mus musculus] 14229 3884 34.10333333 38.34 0.168937579 Up 0.367887096 Fkbp5 FK506 binding protein 5 K09571|1|0.0|878|mmu:14229|FK506-binding protein 4/5 [EC:5.2.1.8] - - - gi|6753884|ref|NP_034350.1|/0/peptidyl-prolyl cis-trans isomerase FKBP5 [Mus musculus] 67731 6936 32.95333333 37.18 0.174102365 Up 0.36774606 Fbxo32 F-box protein 32 K10305|1|0.0|728|mmu:67731|F-box protein 25/32 GO:0043231//intracellular membrane-bounded organelle;GO:0031674//I band - GO:0043500;GO:0032446//protein modification by small protein conjugation gi|13385848|ref|NP_080622.1|/0/F-box only protein 32 [Mus musculus] 54484 2936 9.28 10.81 0.220169813 Up 0.367736658 Mkrn1 "makorin, ring finger protein, 1" K15687|1|0.0|730|mmu:54484|E3 ubiquitin-protein ligase makorin [EC:2.3.2.27] - GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0097159//organic cyclic compound binding GO:0032446//protein modification by small protein conjugation gi|148229622|ref|NP_061280.2|/0/E3 ubiquitin-protein ligase makorin-1 isoform 1 [Mus musculus] 433416 629 0.51 0.17 -1.584962501 Down 0.367595622 Gm13547 predicted gene 13547 K20358|1|1e-08|61.6|rno:64528|golgin subfamily A member 2 - - - gi|294345485|ref|NP_001170863.1|/8.85634e-68/uncharacterized protein LOC433416 [Mus musculus] 22122 1329 13.63 15.61666667 0.196300985 Up 0.36758622 Tsta3 tissue specific transplantation antigen P35B K02377|1|3e-179|630|mmu:22122|GDP-L-fucose synthase [EC:1.1.1.271] - "GO:0036094//small molecule binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding" GO:0008219//cell death;GO:0042350//GDP-L-fucose biosynthetic process "gi|148697557|gb|EDL29504.1|/0/tissue specific transplantation antigen P35B, isoform CRA_b, partial [Mus musculus]" 19329 1825 0.9 0.47 -0.937264245 Down 0.367435782 Rab17 "RAB17, member RAS oncogene family" K07909|1|4e-106|387|mmu:19329|Ras-related protein Rab-17 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0032550 GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization;GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization "gi|15341954|gb|AAH13170.1|/3.76647e-105/RAB17, member RAS oncogene family [Mus musculus]" 20345 2604 3.233333333 4.076666667 0.334367751 Up 0.36738877 Selplg "selectin, platelet (p-selectin) ligand" K06544|1|0.0|765|mmu:20345|selectin P ligand GO:0031224//intrinsic component of membrane - GO:0045123//cellular extravasation;GO:0007159//leukocyte cell-cell adhesion;GO:0070741//response to interleukin-6 gi|159110803|ref|NP_033177.3|/0/P-selectin glycoprotein ligand 1 precursor [Mus musculus] 26401 6963 2.526666667 1.87 -0.434197078 Down 0.367360563 Map3k1 mitogen-activated protein kinase kinase kinase 1 K04416|1|0.0|2442|mmu:26401|mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25] GO:0043232 GO:0008289//lipid binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0004708//MAP kinase kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0032550;GO:0019901//protein kinase binding;GO:0046914//transition metal ion binding GO:0006915//apoptotic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0009612//response to mechanical stimulus;GO:0000186//activation of MAPKK activity;GO:0016567//protein ubiquitination;GO:0016477//cell migration;GO:0001654//eye development;GO:0051403//stress-activated MAPK cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0051017//actin filament bundle assembly;GO:0030041//actin filament polymerization;GO:0000187//activation of MAPK activity;GO:0009611//response to wounding gi|101944546|ref|NP_036075.2|/0/mitogen-activated protein kinase kinase kinase 1 [Mus musculus] 381668 4033 22.86 25.86333333 0.178082822 Up 0.36735116 Fbrsl1 fibrosin-like 1 - - - - - 20498 3826.01 25.32 22.32 -0.181940378 Down 0.36735116 Slc12a4 "solute carrier family 12, member 4" "K14427|1|0.0|1151|mmu:20498|solute carrier family 12 (potassium/chloride transporter), member 4/5/6" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0015377//cation:chloride symporter activity;GO:0015377//cation:chloride symporter activity;GO:0015377//cation:chloride symporter activity GO:0044763;GO:0030001//metal ion transport;GO:0044763;GO:0030001//metal ion transport;GO:0044763;GO:0030001//metal ion transport gi|359374219|ref|NP_001240733.1|/0/solute carrier family 12 member 4 isoform 1 [Mus musculus] 75764 3668.88 4.056666667 4.983333333 0.296816316 Up 0.367332355 Slx1b SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) K15078|1|2e-103|270|mmu:75764|structure-specific endonuclease subunit SLX1 [EC:3.6.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0043169//cation binding;GO:0016889//endodeoxyribonuclease activity, producing 3'-phosphomonoesters;GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters;GO:0043169//cation binding;GO:0016889//endodeoxyribonuclease activity, producing 3'-phosphomonoesters;GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters" GO:0000729//DNA double-strand break processing;GO:0000729//DNA double-strand break processing "gi|148685467|gb|EDL17414.1|/2.72219e-127/GIY-YIG domain containing 2, isoform CRA_d, partial [Mus musculus]" 17925 7240.07 8.13 6.863333333 -0.244345928 Down 0.367304148 Myo9b myosin IXb K10360|1|0.0|3529|mmu:17925|myosin IX - - - gi|755525826|ref|XP_011240573.1|/0/PREDICTED: unconventional myosin-IXb isoform X15 [Mus musculus] 67272 689.13 0.29 0.666666667 1.200912694 Up 0.367275941 Cmtm5 CKLF-like MARVEL transmembrane domain containing 5 - GO:0031224//intrinsic component of membrane;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0044421 GO:0005102//receptor binding;GO:0005102//receptor binding GO:0042221//response to chemical;GO:0042221//response to chemical gi|347582634|ref|NP_083666.1|/4.00736e-43/CKLF-like MARVEL transmembrane domain-containing protein 5 isoform 1 [Mus musculus] 73363 967 0.523333333 0.966666667 0.885288341 Up 0.367247734 1700056E22Rik RIKEN cDNA 1700056E22 gene - - - - gi|294979199|ref|NP_082792.1|/2.23317e-109/uncharacterized protein LOC73363 [Mus musculus] 217866 6718 25.97 22.98333333 -0.176257963 Down 0.367219527 Cdc42bpb CDC42 binding protein kinase beta K16307|1|0.0|3239|mmu:217866|serine/threonine-protein kinase MRCK [EC:2.7.11.1] GO:0030054//cell junction;GO:0015629//actin cytoskeleton;GO:0016020//membrane GO:0043169//cation binding;GO:0032550;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity;GO:0017016//Ras GTPase binding;GO:0008289//lipid binding GO:0048870//cell motility;GO:0006464//cellular protein modification process;GO:0030036//actin cytoskeleton organization;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction gi|283135190|ref|NP_898837.2|/0/serine/threonine-protein kinase MRCK beta [Mus musculus] 54135 2177 0.95 1.47 0.629816737 Up 0.367097296 Lsr lipolysis stimulated lipoprotein receptor - GO:0034358//plasma lipoprotein particle;GO:0016020//membrane;GO:0034358//plasma lipoprotein particle;GO:0016020//membrane;GO:0034385;GO:0031224//intrinsic component of membrane GO:0071813//lipoprotein particle binding;GO:0008289//lipid binding;GO:0038024//cargo receptor activity;GO:0071813//lipoprotein particle binding;GO:0008289//lipid binding;GO:0038024//cargo receptor activity;GO:0071813//lipoprotein particle binding;GO:0008289//lipid binding;GO:0038024//cargo receptor activity GO:0006629//lipid metabolic process;GO:0007275//multicellular organism development;GO:0044767//single-organism developmental process;GO:0015031//protein transport;GO:0006629//lipid metabolic process;GO:0007275//multicellular organism development;GO:0044767//single-organism developmental process;GO:0015031//protein transport;GO:0006629//lipid metabolic process;GO:0007275//multicellular organism development;GO:0044767//single-organism developmental process;GO:0015031//protein transport "gi|1236083|gb|AAA92719.1|/0/Lisch7, partial [Mus musculus]" 448850 983 5.24 6.303333333 0.266548146 Up 0.367087893 Znhit3 "zinc finger, HIT type 3" "K05283|1|5e-64|246|ecb:100071410|phosphatidylinositol glycan, class W [EC:2.3.-.-];K03691|2|1e-13|79.3|tsp:Tsp_00008|peptide-O-fucosyltransferase [EC:2.4.1.221]" - GO:0043169//cation binding - gi|52421332|ref|NP_001005223.1|/4.81921e-83/zinc finger HIT domain-containing protein 3 [Mus musculus] 67333 6076.44 6.14 5.076666667 -0.27435712 Down 0.367087893 Stk35 serine/threonine kinase 35 K08859|1|0.0|919|mmu:67333|serine/threonine kinase 35 [EC:2.7.11.1] - - - gi|148696300|gb|EDL28247.1|/0/serine/threonine kinase 35 [Mus musculus] 67049 2012 2.66 1.993333333 -0.416243262 Down 0.367040882 Pus3 pseudouridine synthase 3 K01855|1|0.0|974|mmu:67049|tRNA pseudouridine38/39 synthase [EC:5.4.99.45] GO:0043231//intracellular membrane-bounded organelle GO:0016866//intramolecular transferase activity;GO:0003676//nucleic acid binding GO:0006399//tRNA metabolic process;GO:0001522//pseudouridine synthesis gi|227499255|ref|NP_075781.3|/0/tRNA pseudouridine(38/39) synthase [Mus musculus] 78670 1276 16.34333333 18.67666667 0.192534731 Up 0.367031479 Plekhj1 "pleckstrin homology domain containing, family J member 1" K01109|1|7e-12|74.3|crg:105321544|inositol polyphosphate-4-phosphatase [EC:3.1.3.66] - GO:0008289//lipid binding - gi|145966842|ref|NP_076389.2|/6.7322e-89/pleckstrin homology domain-containing family J member 1 [Mus musculus] 100502602 1165 2.38 3.106666667 0.384405881 Up 0.366937455 Gm19277 "predicted gene, 19277" - - - - "gi|148672489|gb|EDL04436.1|/1.209e-33/mCG63074, isoform CRA_a [Mus musculus]" 225845 3523 32.58666667 36.68666667 0.170974044 Up 0.366890443 Pla2g16 "phospholipase A2, group XVI" K16817|1|4e-63|246|mmu:225845|HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4] - - - - 110119 1757 73.09666667 65.58333333 -0.156476388 Down 0.366815224 Mpi mannose phosphate isomerase K01809|1|0.0|840|mmu:110119|mannose-6-phosphate isomerase [EC:5.3.1.8] GO:0044424 "GO:0046914//transition metal ion binding;GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses" GO:0009226//nucleotide-sugar biosynthetic process;GO:0019318//hexose metabolic process gi|91206392|ref|NP_080113.1|/0/mannose-6-phosphate isomerase [Mus musculus] 229595 3972.25 22.32 25.28333333 0.179849653 Up 0.36679642 Adamtsl4 ADAMTS-like 4 K08632|1|5e-85|319|pps:100995425|a disintegrin and metalloproteinase with thrombospondin motifs 18 [EC:3.4.24.-] GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix GO:0004175//endopeptidase activity;GO:0019899//enzyme binding;GO:0004175//endopeptidase activity;GO:0019899//enzyme binding GO:0043062//extracellular structure organization;GO:0006915//apoptotic process;GO:0043062//extracellular structure organization;GO:0006915//apoptotic process gi|30089697|ref|NP_659148.2|/0/ADAMTS-like protein 4 precursor [Mus musculus] 57780 679 1.126666667 1.673333333 0.570664118 Up 0.3667212 Fxyd7 FXYD domain-containing ion transport regulator 7 K13364|1|2e-39|164|mmu:57780|FXYD domain-containing ion transport regulator 7 GO:0031224//intrinsic component of membrane GO:0019899//enzyme binding GO:0006811//ion transport gi|38174623|gb|AAH61101.1|/3.04111e-75/Fxyd7 protein [Mus musculus] 67432 1635 0.473333333 0.903333333 0.932401922 Up 0.366683591 Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 K18123|1|0.0|644|mmu:67432|4-hydroxy-2-oxoglutarate aldolase [EC:4.1.3.16] GO:0043231//intracellular membrane-bounded organelle GO:0016832//aldehyde-lyase activity;GO:0042802//identical protein binding GO:0043648//dicarboxylic acid metabolic process;GO:0006090//pyruvate metabolic process;GO:0046185//aldehyde catabolic process;GO:0019471//4-hydroxyproline metabolic process "gi|13385656|ref|NP_080428.1|/0/4-hydroxy-2-oxoglutarate aldolase, mitochondrial precursor [Mus musculus]" 217335 5404 4.743333333 5.75 0.2776607 Up 0.366636579 Fbf1 Fas (TNFRSF6) binding factor 1 K16471|1|0.0|1762|mmu:217335|Fas-binding factor 1 GO:0043232 GO:0005488//binding GO:0030010//establishment of cell polarity;GO:0007043//cell-cell junction assembly gi|144922653|ref|NP_766159.3|/0/fas-binding factor 1 [Mus musculus] 12955 888.12 2945.836667 3273.883333 0.15232547 Up 0.366580165 Cryab "crystallin, alpha B" "K09542|1|9e-98|342|pale:102887587|crystallin, alpha B" GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0031674//I band;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0031674//I band;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0031674//I band;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0031674//I band GO:0005198//structural molecule activity;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0015631//tubulin binding;GO:0005198//structural molecule activity;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0015631//tubulin binding;GO:0005198//structural molecule activity;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0015631//tubulin binding;GO:0005198//structural molecule activity;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0015631//tubulin binding GO:0000226//microtubule cytoskeleton organization;GO:0003012//muscle system process;GO:0010467//gene expression;GO:0043010//camera-type eye development;GO:0044267//cellular protein metabolic process;GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0000302//response to reactive oxygen species;GO:0051259//protein oligomerization;GO:0000165//MAPK cascade;GO:0019318//hexose metabolic process;GO:0043623//cellular protein complex assembly;GO:0032386//regulation of intracellular transport;GO:0072593//reactive oxygen species metabolic process;GO:0016049//cell growth;GO:0000226//microtubule cytoskeleton organization;GO:0003012//muscle system process;GO:0010467//gene expression;GO:0043010//camera-type eye development;GO:0044267//cellular protein metabolic process;GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0000302//response to reactive oxygen species;GO:0051259//protein oligomerization;GO:0000165//MAPK cascade;GO:0019318//hexose metabolic process;GO:0043623//cellular protein complex assembly;GO:0032386//regulation of intracellular transport;GO:0072593//reactive oxygen species metabolic process;GO:0016049//cell growth;GO:0000226//microtubule cytoskeleton organization;GO:0003012//muscle system process;GO:0010467//gene expression;GO:0043010//camera-type eye development;GO:0044267//cellular protein metabolic process;GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0000302//response to reactive oxygen species;GO:0051259//protein oligomerization;GO:0000165//MAPK cascade;GO:0019318//hexose metabolic process;GO:0043623//cellular protein complex assembly;GO:0032386//regulation of intracellular transport;GO:0072593//reactive oxygen species metabolic process;GO:0016049//cell growth;GO:0000226//microtubule cytoskeleton organization;GO:0003012//muscle system process;GO:0010467//gene expression;GO:0043010//camera-type eye development;GO:0044267//cellular protein metabolic process;GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0000302//response to reactive oxygen species;GO:0051259//protein oligomerization;GO:0000165//MAPK cascade;GO:0019318//hexose metabolic process;GO:0043623//cellular protein complex assembly;GO:0032386//regulation of intracellular transport;GO:0072593//reactive oxygen species metabolic process;GO:0016049//cell growth gi|759135282|ref|XP_011363711.1|/1.96248e-113/PREDICTED: alpha-crystallin B chain [Pteropus vampyrus] 16332 4800.32 70.95 63.63 -0.157095563 Down 0.366401519 Inppl1 inositol polyphosphate phosphatase-like 1 "K15909|1|0.0|2100|mmu:16332|phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]" GO:0031252//cell leading edge;GO:0030864//cortical actin cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0031252//cell leading edge;GO:0030864//cortical actin cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0019904//protein domain specific binding;GO:0046030//inositol trisphosphate phosphatase activity;GO:0043168//anion binding;GO:0019904//protein domain specific binding;GO:0046030//inositol trisphosphate phosphatase activity;GO:0043168//anion binding GO:0010467//gene expression;GO:0043405//regulation of MAP kinase activity;GO:0046474//glycerophospholipid biosynthetic process;GO:0019318//hexose metabolic process;GO:0030031//cell projection assembly;GO:0046488//phosphatidylinositol metabolic process;GO:0010975//regulation of neuron projection development;GO:0022610;GO:0006260//DNA replication;GO:0009968//negative regulation of signal transduction;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0043647//inositol phosphate metabolic process;GO:0016192//vesicle-mediated transport;GO:0030036//actin cytoskeleton organization;GO:0008286//insulin receptor signaling pathway;GO:0010467//gene expression;GO:0043405//regulation of MAP kinase activity;GO:0046474//glycerophospholipid biosynthetic process;GO:0019318//hexose metabolic process;GO:0030031//cell projection assembly;GO:0046488//phosphatidylinositol metabolic process;GO:0010975//regulation of neuron projection development;GO:0022610;GO:0006260//DNA replication;GO:0009968//negative regulation of signal transduction;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0043647//inositol phosphate metabolic process;GO:0016192//vesicle-mediated transport;GO:0030036//actin cytoskeleton organization;GO:0008286//insulin receptor signaling pathway "gi|170172575|ref|NP_034697.2|/0/phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 [Mus musculus]" 11770 646 1452.576667 1614.783333 0.152726291 Up 0.36636391 Fabp4 "fatty acid binding protein 4, adipocyte" "K08753|1|3e-69|263|mmu:11770|fatty acid-binding protein 4, adipocyte" - - - - 73173 5168 0.956666667 0.52 -0.879504708 Down 0.366335703 Pcdh18 protocadherin 18 K16499|1|0.0|2157|mmu:73173|protocadherin delta 2 - - - - 80733 1125 1.29 0.796666667 -0.695322948 Down 0.366204069 Car15 carbonic anhydrase 15 K01672|1|2e-153|544|mmu:80733|carbonic anhydrase [EC:4.2.1.1] GO:0031225//anchored component of membrane GO:0003824//catalytic activity;GO:0043169//cation binding - gi|74203547|dbj|BAE20923.1|/8.76226e-159/unnamed protein product [Mus musculus] 68612 931 5.036666667 6.083333333 0.272392803 Up 0.366175862 Ube2c ubiquitin-conjugating enzyme E2C K06688|1|4e-96|353|mmu:68612|ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23] GO:0000152//nuclear ubiquitin ligase complex GO:0032550;GO:0019787//ubiquitin-like protein transferase activity GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010993//regulation of ubiquitin homeostasis;GO:0000209//protein polyubiquitination;GO:0007096//regulation of exit from mitosis gi|635047523|ref|XP_007960333.1|/2.25658e-95/PREDICTED: ubiquitin-conjugating enzyme E2 C-like isoform X1 [Chlorocebus sabaeus] 17534 5801 6.733333333 5.636666667 -0.256478633 Down 0.366157057 Mrc2 "mannose receptor, C type 2" "K06560|1|0.0|3009|mmu:17534|mannose receptor, C type" GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0016192//vesicle-mediated transport gi|568972029|ref|XP_006532469.1|/0/PREDICTED: C-type mannose receptor 2 isoform X1 [Mus musculus] 18150 866 7.783333333 9.153333333 0.233909076 Up 0.366091241 Npm3 nucleoplasmin 3 K11278|1|4e-71|270|mmu:18150|nucleophosmin 3 GO:0031981//nuclear lumen GO:0005488//binding "GO:0006351//transcription, DNA-templated;GO:0042254//ribosome biogenesis" gi|6679110|ref|NP_032749.1|/2.8812e-70/nucleoplasmin-3 [Mus musculus] 216438 1998 3.216666667 4.043333333 0.329978703 Up 0.366034826 9-Mar membrane-associated ring finger (C3HC4) 9 K10659|1|2e-127|443|ptr:452026|E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27] GO:0005794//Golgi apparatus - - gi|586457879|ref|XP_006878396.1|/5.77522e-130/PREDICTED: LOW QUALITY PROTEIN: membrane-associated ring finger (C3HC4) 9 [Chrysochloris asiatica] 68563 506 12.79333333 14.73333333 0.203691658 Up 0.36596901 Dpm3 dolichyl-phosphate mannosyltransferase polypeptide 3 K09659|1|3e-37|155|rno:100910177|dolichyl-phosphate mannosyltransferase polypeptide 3 GO:0031501//mannosyltransferase complex;GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0000030//mannosyltransferase activity GO:0010608//posttranscriptional regulation of gene expression;GO:0006497//protein lipidation gi|672078629|ref|XP_003751559.2|/2.02736e-36/PREDICTED: dolichol-phosphate mannosyltransferase subunit 3-like [Rattus norvegicus] 69116 15901 14.78333333 12.84666667 -0.202577533 Down 0.36596901 Ubr4 ubiquitin protein ligase E3 component n-recognin 4 K10691|1|0.0|9307|mmu:69116|E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0005515//protein binding - gi|237820660|ref|NP_001153791.1|/0/E3 ubiquitin-protein ligase UBR4 [Mus musculus] 100042295 874 1.933333333 1.353333333 -0.514573173 Down 0.365959607 Gm3776 predicted gene 3776 K00799|1|7e-123|442|mmu:14857|glutathione S-transferase [EC:2.5.1.18] GO:0031965//nuclear membrane;GO:0044444//cytoplasmic part "GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0072341//modified amino acid binding" GO:0006805//xenobiotic metabolic process;GO:0044767//single-organism developmental process "gi|38173961|gb|AAH61134.1|/1.13735e-122/Glutathione S-transferase, alpha 1 (Ya) [Mus musculus]" 56470 1427.99 3.666666667 4.556666667 0.313509719 Up 0.365809169 Rgs19 regulator of G-protein signaling 19 K16449|1|3e-114|414|mmu:56470|regulator of G-protein signaling - - - - 67680 1091 839.5733333 756.7666667 -0.149807801 Down 0.365762157 Sdhb "succinate dehydrogenase complex, subunit B, iron sulfur (Ip)" K00235|1|4e-151|536|mmu:67680|succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1] GO:0005746//mitochondrial respiratory chain GO:0048038//quinone binding;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0000104//succinate dehydrogenase activity GO:0022900//electron transport chain;GO:0043648//dicarboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0051234//establishment of localization "gi|34328286|ref|NP_075863.2|/3.17846e-150/succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial precursor [Mus musculus]" 22234 3719 3.396666667 4.246666667 0.322211226 Up 0.365696341 Ugcg UDP-glucose ceramide glucosyltransferase K00720|1|0.0|786|mmu:22234|ceramide glucosyltransferase [EC:2.4.1.80] GO:0031224//intrinsic component of membrane;GO:0012505//endomembrane system GO:0035251//UDP-glucosyltransferase activity GO:0009888//tissue development;GO:0006678//glucosylceramide metabolic process;GO:0006796//phosphate-containing compound metabolic process gi|7106443|ref|NP_035803.1|/0/ceramide glucosyltransferase [Mus musculus] 13730 2721 24.00666667 21.14 -0.183459722 Down 0.365696341 Emp1 epithelial membrane protein 1 K19289|1|2e-24|117|cmk:103175419|peripheral myelin protein 22 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0040007//growth;GO:0040007//growth;GO:0040007//growth gi|431908359|gb|ELK11956.1|/8.63214e-80/hypothetical protein PAL_GLEAN10015630 [Pteropus alecto] 78521 4691 8.143333333 6.896666667 -0.239720218 Down 0.365677536 B230219D22Rik RIKEN cDNA B230219D22 gene - - - - "gi|148709277|gb|EDL41223.1|/2.66988e-122/RIKEN cDNA B230219D22, partial [Mus musculus]" 208634 2064 0.4 0.09 -2.152003093 Down 0.365649329 Tspan10 tetraspanin 10 K17351|1|3e-166|588|mmu:208634|tetraspanin-10 - - - - 68050 2383 12.78666667 14.71333333 0.202483909 Up 0.365611719 Akirin1 akirin 1 - GO:0005635//nuclear envelope;GO:0031981//nuclear lumen - - gi|31982645|ref|NP_075912.2|/8.07484e-98/akirin-1 [Mus musculus] 231086 2060.29 697.9366667 773.7966667 0.148858387 Up 0.365583512 Hadhb "hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit" K07509|1|0.0|934|mmu:231086|acetyl-CoA acyltransferase [EC:2.3.1.16] GO:0031966//mitochondrial membrane;GO:0019866//organelle inner membrane;GO:0005759//mitochondrial matrix;GO:0031966//mitochondrial membrane;GO:0019866//organelle inner membrane;GO:0005759//mitochondrial matrix;GO:0031966//mitochondrial membrane;GO:0019866//organelle inner membrane;GO:0005759//mitochondrial matrix "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0016836//hydro-lyase activity;GO:0016408//C-acyltransferase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0016836//hydro-lyase activity;GO:0016408//C-acyltransferase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0016836//hydro-lyase activity;GO:0016408//C-acyltransferase activity" GO:0009062//fatty acid catabolic process;GO:0009062//fatty acid catabolic process;GO:0009062//fatty acid catabolic process "gi|148705321|gb|EDL37268.1|/0/mCG11629, isoform CRA_d, partial [Mus musculus]" 20402 9100 68.18333333 61.22666667 -0.15525899 Down 0.36557411 Zfp106 zinc finger protein 106 K18188|1|5e-33|147|cin:100178710|protein PET117;K10260|3|5e-24|117|tad:TRIADDRAFT_24498|F-box and WD-40 domain protein 7 - - - gi|109948269|ref|NP_035873.2|/0/zinc finger protein 106 [Mus musculus] 71820 1812 4.61 5.61 0.28323402 Up 0.365564707 Wdr34 WD repeat domain 34 "K11143|1|2e-26|123|xma:102231521|dynein intermediate chain 2, axonemal;K10415|2|2e-24|116|spu:590595|dynein intermediate chain, cytosolic" GO:0044424 - - gi|139948827|ref|NP_001008498.2|/0/WD repeat-containing protein 34 [Mus musculus] 20918 1279 658.4133333 728.9566667 0.146839503 Up 0.365480086 Eif1 eukaryotic translation initiation factor 1 K03113|1|1e-55|219|phd:102331936|translation initiation factor 1 GO:0044424 "GO:0008135//translation factor activity, RNA binding" GO:0006413//translational initiation;GO:0050896//response to stimulus;GO:0007549//dosage compensation gi|611991798|ref|XP_001364419.2|/3.62882e-58/PREDICTED: uncharacterized protein LOC100012315 [Monodelphis domestica] 100037262 1401 1.24 1.8 0.537656786 Up 0.365470683 Gm12359 predicted gene 12359 K14323|1|1e-17|93.6|chx:102177095|protein CASC3;K13163|4|1e-09|67.0|mmu:74026|male-specific lethal 1 - - - - 22202 3981 0.906666667 1.413333333 0.640457613 Up 0.365451879 Uba1y "ubiquitin-activating enzyme, Chr Y" K03178|1|0.0|2066|mmu:22202|ubiquitin-activating enzyme E1 [EC:6.2.1.45] - - - - 216527 1868.55 12.65666667 14.58 0.204093221 Up 0.365273233 Ccm2 cerebral cavernous malformation 2 - - - - - 319876 4968.01 23.70333333 20.86333333 -0.18412028 Down 0.365198014 Cobll1 Cobl-like 1 K18623|1|3e-56|224|cmk:103181198|protein cordon-bleu - - - "gi|148695053|gb|EDL27000.1|/0/Cobl-like 1, isoform CRA_b, partial [Mus musculus]" 67155 4667.86 15.69333333 17.94333333 0.193296105 Up 0.365188612 Smarca2 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2" K11647|1|2e-94|308|ngi:103740994|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-] GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0090544//BAF-type complex;GO:0005856//cytoskeleton "GO:0001104//RNA polymerase II transcription cofactor activity;GO:0000975//regulatory region DNA binding;GO:0042623//ATPase activity, coupled" GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0034728//nucleosome organization;GO:0035886//vascular smooth muscle cell differentiation;GO:0016049//cell growth;GO:0016568//chromatin modification gi|51593084|ref|NP_035546.2|/0/probable global transcription activator SNF2L2 isoform 1 [Mus musculus] 109658 4645.99 10.27 8.793333333 -0.223954118 Down 0.365169807 Txlna taxilin alpha K06106|1|1e-26|125|smm:Smp_164620|cortactin;K10352|3|9e-06|56.2|aag:AaeL_AAEL001411|myosin heavy chain GO:0044424;GO:0044424 GO:0000149//SNARE binding;GO:0000149//SNARE binding GO:0046649//lymphocyte activation;GO:0046649//lymphocyte activation "gi|148698222|gb|EDL30169.1|/0/taxilin alpha, isoform CRA_c, partial [Mus musculus]" 100382 2745 3.156666667 2.433333333 -0.375467962 Down 0.36510399 AW011738 expressed sequence AW011738 - - - - gi|74140282|dbj|BAE33835.1|/1.38622e-80/unnamed protein product [Mus musculus] 76899 4793 3.143333333 2.423333333 -0.375302407 Down 0.36510399 Golga1 "golgi autoantigen, golgin subfamily a, 1" K16731|1|0.0|1227|mmu:76899|golgin subfamily A member 1 GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - "gi|148694893|gb|EDL26840.1|/0/golgi autoantigen, golgin subfamily a, 1, isoform CRA_d, partial [Mus musculus]" 73162 1670 8.07 6.833333333 -0.23997917 Down 0.364972357 Otud3 OTU domain containing 3 K13717|1|0.0|669|mmu:73162|OTU domain-containing protein 3 [EC:3.4.19.12] - - - gi|254675322|ref|NP_082729.1|/0/OTU domain-containing protein 3 [Mus musculus] 69871 939 6.93 8.173333333 0.238069221 Up 0.364972357 Ppp1r35 "protein phosphatase 1, regulatory subunit 35" K17574|1|2e-80|301|mmu:69871|protein phosphatase 1 regulatory subunit 35 - - - - 432442 3140 8.06 6.82 -0.2410081 Down 0.364972357 Akap7 A kinase (PRKA) anchor protein 7 K16524|1|7e-167|590|mmu:432442|A-kinase anchor protein 7 GO:0032991//macromolecular complex;GO:0030133//transport vesicle;GO:0044459;GO:0042383//sarcolemma;GO:0005783//endoplasmic reticulum GO:0051018//protein kinase A binding;GO:0032550;GO:0019900//kinase binding GO:0044260;GO:0033036 gi|568965505|ref|XP_006512849.1|/0/PREDICTED: A-kinase anchor protein 7 isoform X2 [Mus musculus] 73990 1016 6.8 8.043333333 0.242258763 Up 0.364972357 4930455C13Rik RIKEN cDNA 4930455C13 gene K14416|1|2e-43|178|mmu:56422|elongation factor 1 alpha-like protein - - - - 278180 1432 0.426666667 0.85 0.994353437 Up 0.36494415 Vsig4 V-set and immunoglobulin domain containing 4 K19822|1|4e-160|566|mmu:278180|V-set and immunoglobulin domain-containing protein 4 - - GO:0001818//negative regulation of cytokine production;GO:0042098//T cell proliferation gi|29244314|ref|NP_808457.1|/3.27743e-159/V-set and immunoglobulin domain-containing protein 4 precursor [Mus musculus] 80987 2870 6.26 7.423333333 0.245904495 Up 0.364850126 Nckipsd NCK interacting protein with SH3 domain - - GO:0019904//protein domain specific binding - gi|49258190|ref|NP_109654.2|/0/NCK-interacting protein with SH3 domain [Mus musculus] 109050 4651.32 6.256666667 7.42 0.246024943 Up 0.364850126 Fam212b "family with sequence similarity 212, member B" - - - - gi|568921500|ref|XP_006500922.1|/3.57873e-148/PREDICTED: protein FAM212B isoform X1 [Mus musculus] 66895 1872 6.03 7.193333333 0.254502457 Up 0.364850126 Pxdc1 PX domain containing 1 - - GO:0005543//phospholipid binding GO:0044763 gi|115292445|ref|NP_080107.3|/1.05402e-126/PX domain-containing protein 1 [Mus musculus] 102636514 553 21.14333333 23.95 0.179822815 Up 0.364803114 LOC102636514 uncharacterized LOC102636514 - - - - "gi|148696664|gb|EDL28611.1|/6.68184e-51/mCG117600, isoform CRA_b, partial [Mus musculus]" 23879 3002 56.49666667 63.1 0.159474255 Up 0.364727895 Fxr2 "fragile X mental retardation, autosomal homolog 2" K15516|1|0.0|1021|mmu:23879|fragile X mental retardation protein GO:0015934//large ribosomal subunit GO:0003676//nucleic acid binding - gi|83921589|ref|NP_035944.2|/0/fragile X mental retardation syndrome-related protein 2 [Mus musculus] 100503659 3007.11 4.716666667 5.71 0.275723098 Up 0.364671481 Cbarp "calcium channel, voltage-dependent, beta subunit associated regulatory protein" - - - - gi|568966132|ref|XP_006513031.1|/0/PREDICTED: protein Dos isoform X3 [Mus musculus] 24075 787 57.65 64.21 0.155477391 Up 0.364624469 Taf10 TATA-box binding protein associated factor 10 K03134|1|7e-63|242|mmu:24075|transcription initiation factor TFIID subunit 10 GO:0070461//SAGA-type complex;GO:0005667//transcription factor complex GO:0005515//protein binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0040007//growth;GO:0006461//protein complex assembly;GO:0006915//apoptotic process;GO:0001889//liver development;GO:0051098//regulation of binding" gi|46518499|ref|NP_064408.2|/5.31747e-62/transcription initiation factor TFIID subunit 10 [Mus musculus] 20342 1695 10.30666667 8.84 -0.221459544 Down 0.364577457 Selenbp2 selenium binding protein 2 K17285|1|0.0|988|mmu:20342|selenium-binding protein 1 GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen GO:0005488//binding GO:0045184//establishment of protein localization;GO:0045444//fat cell differentiation gi|9507079|ref|NP_062287.1|/0/selenium-binding protein 2 [Mus musculus] 13048 4954 3.63 4.51 0.313157885 Up 0.364568054 Cux2 cut-like homeobox 2 K09313|1|0.0|2363|mmu:13048|homeobox protein cut-like GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0010033//response to organic substance" gi|568936848|ref|XP_006530220.1|/0/PREDICTED: homeobox protein cut-like 2 isoform X2 [Mus musculus] 17896 883 2.23 2.93 0.393856955 Up 0.364502238 Myl4 "myosin, light polypeptide 4" K12750|1|1e-88|328|cge:100771007|myosin light chain 4 GO:0015629//actin cytoskeleton;GO:0030017//sarcomere GO:0046872//metal ion binding;GO:0003779//actin binding GO:0006941//striated muscle contraction;GO:0043462//regulation of ATPase activity gi|537142731|gb|ERE68610.1|/9.19164e-88/myosin light chain 4-like protein [Cricetulus griseus] 69582 4178 55.84 62.34 0.158859213 Up 0.364427019 Plekhm2 "pleckstrin homology domain containing, family M (with RUN domain) member 2" K15348|1|0.0|1864|mmu:69582|pleckstrin homology domain-containing family M member 2 GO:0044424 GO:0008092//cytoskeletal protein binding;GO:0008289//lipid binding GO:0006996//organelle organization gi|226958488|ref|NP_001028322.1|/0/pleckstrin homology domain-containing family M member 2 [Mus musculus] 85308 805 20.96 23.74 0.179681218 Up 0.364398812 Emc9 ER membrane protein complex subunit 9 K06697|1|3e-38|160|oaa:100073774|proteasome activator subunit 2 (PA28 beta) GO:0030176//integral component of endoplasmic reticulum membrane - - gi|14994310|ref|NP_149158.1|/1.60957e-117/ER membrane protein complex subunit 9 [Mus musculus] 66834 686 438.2733333 394.3466667 -0.152366453 Down 0.364380007 Acot13 acyl-CoA thioesterase 13 K17362|1|2e-64|247|mmu:66834|acyl-coenzyme A thioesterase 13 [EC:3.1.2.-] GO:0043231//intracellular membrane-bounded organelle GO:0016289//CoA hydrolase activity GO:0051260//protein homooligomerization gi|13385260|ref|NP_080066.1|/1.23952e-63/acyl-coenzyme A thioesterase 13 [Mus musculus] 319179 1657.89 1.113333333 1.65 0.567580422 Up 0.364295385 Hist1h2be "histone cluster 1, H2be" K11252|1|7e-46|184|cge:100761268|histone H2B GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|344238174|gb|EGV94277.1|/1.21999e-43/histone H2B type 1 [Cricetulus griseus] 21952 1086 0.823333333 1.316666667 0.677341611 Up 0.364229569 Tnni1 "troponin I, skeletal, slow 1" "K10371|1|2e-95|351|cge:100756622|troponin I, slow skeletal muscle" GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament GO:0043169//cation binding;GO:0043169//cation binding GO:0003208//cardiac ventricle morphogenesis;GO:0006936//muscle contraction;GO:0003208//cardiac ventricle morphogenesis;GO:0006936//muscle contraction "gi|625189927|ref|XP_007632658.1|/7.86546e-95/PREDICTED: troponin I, slow skeletal muscle isoform X2 [Cricetulus griseus]" 100217467 101 1.516666667 2.116666667 0.480890047 Up 0.364201361 Snora5c "small nucleolar RNA, H/ACA box 5C" - - - - - 17931 3403 6.056666667 5.03 -0.267965614 Down 0.36415435 Ppp1r12a "protein phosphatase 1, regulatory (inhibitor) subunit 12A" K06270|1|0.0|1327|mmu:17931|protein phosphatase 1 regulatory subunit 12A GO:0005815//microtubule organizing center;GO:0008287//protein serine/threonine phosphatase complex GO:0016791//phosphatase activity;GO:0019900//kinase binding;GO:0030234//enzyme regulator activity GO:0007155//cell adhesion;GO:0006366//transcription from RNA polymerase II promoter;GO:0006913//nucleocytoplasmic transport;GO:0031023//microtubule organizing center organization;GO:0044092//negative regulation of molecular function;GO:0006464//cellular protein modification process;GO:0000087//mitotic M phase;GO:0043666//regulation of phosphoprotein phosphatase activity gi|95772123|ref|NP_082168.1|/0/protein phosphatase 1 regulatory subunit 12A [Mus musculus] 66965 3066 4.966666667 6 0.272684576 Up 0.36415435 Ctu2 cytosolic thiouridylase subunit 2 K14169|1|0.0|959|mmu:66965|cytoplasmic tRNA 2-thiolation protein 2 - - - - 14612 1686 15.82333333 18.02333333 0.187812307 Up 0.364107338 Gja4 "gap junction protein, alpha 4" "K07613|1|0.0|659|mmu:14612|gap junction protein, alpha 4" GO:0005921//gap junction;GO:0031224//intrinsic component of membrane - GO:0070838//divalent metal ion transport;GO:0033555//multicellular organismal response to stress;GO:0009888//tissue development;GO:0001944//vasculature development;GO:0007154//cell communication gi|6680003|ref|NP_032146.1|/0/gap junction alpha-4 protein [Mus musculus] 108816 4551 6.183333333 7.333333333 0.246084337 Up 0.364088533 4933409K07Rik RIKEN cDNA 4933409K07 gene "K04676|1|2e-23|114|cge:100762264|mothers against decapentaplegic homolog 1;K04257|2|1e-11|75.9|mmu:259023|olfactory receptor;K06751|3|1e-11|75.9|mmu:100529082|major histocompatibility complex, class I" - - - gi|49117662|gb|AAH72647.1|/0/RIKEN cDNA 4933409K07 gene [Mus musculus] 15483 1366.33 10.26666667 8.806666667 -0.221299884 Down 0.36407913 Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 K15680|1|2e-160|567|mmu:15483|corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146] GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope;GO:0031090//organelle membrane;GO:0005783//endoplasmic reticulum;GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope;GO:0031090//organelle membrane;GO:0005783//endoplasmic reticulum "GO:0000166//nucleotide binding;GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0003676//nucleic acid binding;GO:0034061//DNA polymerase activity;GO:0008289//lipid binding;GO:0000166//nucleotide binding;GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0003676//nucleic acid binding;GO:0034061//DNA polymerase activity;GO:0008289//lipid binding" GO:0006098//pentose-phosphate shunt;GO:0006694//steroid biosynthetic process;GO:0042537//benzene-containing compound metabolic process;GO:0030323//respiratory tube development;GO:0009991//response to extracellular stimulus;GO:0006706//steroid catabolic process;GO:0032355//response to estradiol;GO:0006260//DNA replication;GO:0006098//pentose-phosphate shunt;GO:0006694//steroid biosynthetic process;GO:0042537//benzene-containing compound metabolic process;GO:0030323//respiratory tube development;GO:0009991//response to extracellular stimulus;GO:0006706//steroid catabolic process;GO:0032355//response to estradiol;GO:0006260//DNA replication "gi|148681002|gb|EDL12949.1|/1.02783e-178/hydroxysteroid 11-beta dehydrogenase 1, partial [Mus musculus]" 66521 1082 60.84666667 54.5 -0.158922001 Down 0.363966302 Rwdd1 RWD domain containing 1 K10640|1|3e-07|58.5|xtr:496760|E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27];K16196|2|7e-06|53.9|tgu:100232582|eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1] - GO:0005488//binding - "gi|148672932|gb|EDL04879.1|/1.85081e-126/RWD domain containing 1, partial [Mus musculus]" 276770 1283.59 319.7166667 354.9766667 0.150930243 Up 0.363815864 Eif5a eukaryotic translation initiation factor 5A K03263|1|8e-88|326|ngi:103752149|translation initiation factor 5A GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network;GO:0005635//nuclear envelope;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part;GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network;GO:0005635//nuclear envelope;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part;GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network;GO:0005635//nuclear envelope;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part;GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network;GO:0005635//nuclear envelope;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part;GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network;GO:0005635//nuclear envelope;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part;GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network;GO:0005635//nuclear envelope;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part;GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network;GO:0005635//nuclear envelope;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part;GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network;GO:0005635//nuclear envelope;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part;GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network;GO:0005635//nuclear envelope;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part "GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0017069//snRNA binding;GO:0008135//translation factor activity, RNA binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0017069//snRNA binding;GO:0008135//translation factor activity, RNA binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0017069//snRNA binding;GO:0008135//translation factor activity, RNA binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0017069//snRNA binding;GO:0008135//translation factor activity, RNA binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0017069//snRNA binding;GO:0008135//translation factor activity, RNA binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0017069//snRNA binding;GO:0008135//translation factor activity, RNA binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0017069//snRNA binding;GO:0008135//translation factor activity, RNA binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0017069//snRNA binding;GO:0008135//translation factor activity, RNA binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0017069//snRNA binding;GO:0008135//translation factor activity, RNA binding" GO:0006415//translational termination;GO:0008283//cell proliferation;GO:0006414//translational elongation;GO:0006886//intracellular protein transport;GO:0012502//induction of programmed cell death;GO:0018205//peptidyl-lysine modification;GO:0006405//RNA export from nucleus;GO:0006415//translational termination;GO:0008283//cell proliferation;GO:0006414//translational elongation;GO:0006886//intracellular protein transport;GO:0012502//induction of programmed cell death;GO:0018205//peptidyl-lysine modification;GO:0006405//RNA export from nucleus;GO:0006415//translational termination;GO:0008283//cell proliferation;GO:0006414//translational elongation;GO:0006886//intracellular protein transport;GO:0012502//induction of programmed cell death;GO:0018205//peptidyl-lysine modification;GO:0006405//RNA export from nucleus;GO:0006415//translational termination;GO:0008283//cell proliferation;GO:0006414//translational elongation;GO:0006886//intracellular protein transport;GO:0012502//induction of programmed cell death;GO:0018205//peptidyl-lysine modification;GO:0006405//RNA export from nucleus;GO:0006415//translational termination;GO:0008283//cell proliferation;GO:0006414//translational elongation;GO:0006886//intracellular protein transport;GO:0012502//induction of programmed cell death;GO:0018205//peptidyl-lysine modification;GO:0006405//RNA export from nucleus;GO:0006415//translational termination;GO:0008283//cell proliferation;GO:0006414//translational elongation;GO:0006886//intracellular protein transport;GO:0012502//induction of programmed cell death;GO:0018205//peptidyl-lysine modification;GO:0006405//RNA export from nucleus;GO:0006415//translational termination;GO:0008283//cell proliferation;GO:0006414//translational elongation;GO:0006886//intracellular protein transport;GO:0012502//induction of programmed cell death;GO:0018205//peptidyl-lysine modification;GO:0006405//RNA export from nucleus;GO:0006415//translational termination;GO:0008283//cell proliferation;GO:0006414//translational elongation;GO:0006886//intracellular protein transport;GO:0012502//induction of programmed cell death;GO:0018205//peptidyl-lysine modification;GO:0006405//RNA export from nucleus;GO:0006415//translational termination;GO:0008283//cell proliferation;GO:0006414//translational elongation;GO:0006886//intracellular protein transport;GO:0012502//induction of programmed cell death;GO:0018205//peptidyl-lysine modification;GO:0006405//RNA export from nucleus gi|823403345|ref|XP_012417162.1|/9.32515e-87/PREDICTED: eukaryotic translation initiation factor 5A-1 isoform X1 [Odobenus rosmarus divergens] 30928 3848 9.013333333 7.683333333 -0.230328401 Down 0.36368423 Zbtb18 zinc finger and BTB domain containing 18 K10490|1|1e-70|271|lcm:102362019|zinc finger and BTB domain-containing protein 3 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003677//DNA binding GO:0022037//metencephalon development;GO:0021543//pallium development;GO:0043009//chordate embryonic development;GO:0042592//homeostatic process;GO:0050794//regulation of cellular process;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter "gi|29748010|gb|AAH50909.1|/0/zinc finger protein 238, partial [Mus musculus]" 100038614 1654 1.353333333 1.923333333 0.507091591 Up 0.363627816 Gm10791 predicted gene 10791 - - - - "gi|148665904|gb|EDK98320.1|/4.13063e-39/mCG129420, isoform CRA_a, partial [Mus musculus]" 16948 4576.55 1.93 1.356666667 -0.508534554 Down 0.363627816 Lox lysyl oxidase K00277|1|0.0|736|mmu:16948|protein-lysine 6-oxidase [EC:1.4.3.13] GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix "GO:0046914//transition metal ion binding;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0046914//transition metal ion binding;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0046914//transition metal ion binding;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor" GO:0009725//response to hormone;GO:0009611//response to wounding;GO:0085029//extracellular matrix assembly;GO:0044710;GO:0030323//respiratory tube development;GO:0009725//response to hormone;GO:0009611//response to wounding;GO:0085029//extracellular matrix assembly;GO:0044710;GO:0030323//respiratory tube development;GO:0009725//response to hormone;GO:0009611//response to wounding;GO:0085029//extracellular matrix assembly;GO:0044710;GO:0030323//respiratory tube development gi|74192826|dbj|BAE34923.1|/0/unnamed protein product [Mus musculus] 58250 5532 1.913333333 1.34 -0.513855235 Down 0.363627816 Chst11 carbohydrate sulfotransferase 11 K01017|1|0.0|726|mmu:58250|chondroitin 4-sulfotransferase 11 [EC:2.8.2.5] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0012505//endomembrane system GO:0034481//chondroitin sulfotransferase activity GO:0033036;GO:0002062//chondrocyte differentiation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0040007//growth;GO:0048562//embryonic organ morphogenesis;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0030326//embryonic limb morphogenesis;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0044723 gi|76559942|ref|NP_067414.2|/0/carbohydrate sulfotransferase 11 [Mus musculus] 223970 3739 1.41 1.993333333 0.499487821 Up 0.363580804 Rmi2 RecQ mediated genome instability 2 K15365|1|1e-65|254|mmu:223970|RecQ-mediated genome instability protein 2 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process gi|242397460|ref|NP_001156404.1|/8.89768e-65/recQ-mediated genome instability protein 2 [Mus musculus] 13177 1091 285.6466667 317.7933333 0.153857166 Up 0.36352439 Eci1 enoyl-Coenzyme A delta isomerase 1 "K13238|1|8e-152|538|mmu:13177|3,2-trans-enoyl-CoA isomerase, mitochondrial [EC:5.3.3.8]" GO:0019866//organelle inner membrane;GO:0044429 "GO:0005515//protein binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds" GO:0009062//fatty acid catabolic process "gi|31981810|ref|NP_034153.2|/6.40439e-151/enoyl-CoA delta isomerase 1, mitochondrial precursor [Mus musculus]" 208647 3318 5.623333333 4.643333333 -0.276264716 Down 0.363505585 Creb3l2 cAMP responsive element binding protein 3-like 2 K09048|1|0.0|860|mmu:208647|cyclic AMP-responsive element-binding protein 3 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0044212//transcription regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0033554//cellular response to stress;GO:0001501//skeletal system development;GO:0030154//cell differentiation;GO:0016482//cytosolic transport;GO:0006351//transcription, DNA-templated;GO:0035966//response to topologically incorrect protein" gi|282400149|ref|NP_848776.2|/0/cyclic AMP-responsive element-binding protein 3-like protein 2 [Mus musculus] 233489 4019.39 58.46333333 52.25 -0.162101051 Down 0.363467975 Picalm phosphatidylinositol binding clathrin assembly protein K20044|1|0.0|1125|ssc:100626535|phosphatidylinositol-binding clathrin assembly protein GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0030128//clathrin coat of endocytic vesicle;GO:0030117//membrane coat;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0012505//endomembrane system;GO:0030136//clathrin-coated vesicle;GO:0030117//membrane coat;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0012505//endomembrane system;GO:0030136//clathrin-coated vesicle;GO:0030117//membrane coat;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0012505//endomembrane system;GO:0030136//clathrin-coated vesicle;GO:0030117//membrane coat;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0012505//endomembrane system;GO:0030136//clathrin-coated vesicle;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0005905//clathrin-coated pit;GO:0030128//clathrin coat of endocytic vesicle GO:0035091//phosphatidylinositol binding;GO:0030276//clathrin binding;GO:0019904//protein domain specific binding;GO:0035091//phosphatidylinositol binding;GO:0030276//clathrin binding;GO:0019904//protein domain specific binding;GO:0035091//phosphatidylinositol binding;GO:0030276//clathrin binding;GO:0019904//protein domain specific binding;GO:0035091//phosphatidylinositol binding;GO:0030276//clathrin binding;GO:0019904//protein domain specific binding;GO:0035091//phosphatidylinositol binding;GO:0030276//clathrin binding;GO:0019904//protein domain specific binding;GO:0035091//phosphatidylinositol binding;GO:0030276//clathrin binding;GO:0019904//protein domain specific binding "GO:0016358//dendrite development;GO:0006351//transcription, DNA-templated;GO:0006901//vesicle coating;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0048534//hematopoietic or lymphoid organ development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0016358//dendrite development;GO:0006351//transcription, DNA-templated;GO:0006901//vesicle coating;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0048534//hematopoietic or lymphoid organ development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0016358//dendrite development;GO:0006351//transcription, DNA-templated;GO:0006901//vesicle coating;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0048534//hematopoietic or lymphoid organ development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0016358//dendrite development;GO:0006351//transcription, DNA-templated;GO:0006901//vesicle coating;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0048534//hematopoietic or lymphoid organ development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0016358//dendrite development;GO:0006351//transcription, DNA-templated;GO:0006901//vesicle coating;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0048534//hematopoietic or lymphoid organ development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0016358//dendrite development;GO:0006351//transcription, DNA-templated;GO:0006901//vesicle coating;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0048534//hematopoietic or lymphoid organ development;GO:0048667//cell morphogenesis involved in neuron differentiation" "gi|148674812|gb|EDL06759.1|/0/phosphatidylinositol binding clathrin assembly protein, isoform CRA_e, partial [Mus musculus]" 73658 2703.6 10.16666667 11.78333333 0.212900972 Up 0.363430366 Spns1 spinster homolog 1 K20225|1|1e-97|360|acs:103282837|capicua transcriptional repressor GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0044763;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0044763 gi|170671720|ref|NP_076201.2|/0/protein spinster homolog 1 [Mus musculus] 66556 1001 279.1366667 308.78 0.145607665 Up 0.363270525 Drap1 Dr1 associated protein 1 (negative cofactor 2 alpha) "K08066|1|3e-08|61.6|hmg:100213726|nuclear transcription factor Y, gamma" GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0003677//DNA binding;GO:0005515//protein binding GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter gi|674094346|ref|XP_008820457.1|/7.79175e-66/PREDICTED: dr1-associated corepressor isoform X3 [Nannospalax galili] 17828 1791 7.513333333 8.83 0.232960328 Up 0.363232916 Bloc1s5 "biogenesis of lysosomal organelles complex-1, subunit 5, muted" K20187|1|2e-101|372|mmu:17828|biogenesis of lysosome-related organelles complex 1 subunit 5 "GO:0031082;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0005488//binding GO:0030030//cell projection organization;GO:0042472//inner ear morphogenesis;GO:0043485//endosome to pigment granule transport;GO:0045597//positive regulation of cell differentiation;GO:0008088//axo-dendritic transport;GO:0048489//synaptic vesicle transport;GO:0048753//pigment granule organization;GO:0032401//establishment of melanosome localization "gi|148708994|gb|EDL40940.1|/1.94055e-114/mCG144029, partial [Mus musculus]" 70296 3487 7.546666667 8.866666667 0.232552288 Up 0.363232916 Tbc1d13 "TBC1 domain family, member 13" K18469|1|2e-26|124|ssc:100626058|TBC1 domain family member 5 GO:0044464 GO:0005488//binding - gi|22122839|ref|NP_666364.1|/0/TBC1 domain family member 13 [Mus musculus] 225028 4176 8.83 7.506666667 -0.234241016 Down 0.363232916 Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 K04406|1|0.0|1680|mmu:225028|mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0030695//GTPase regulator activity;GO:0032550 GO:0035556//intracellular signal transduction gi|594140610|ref|NP_001277274.1|/0/mitogen-activated protein kinase kinase kinase kinase 3 [Mus musculus] 66225 1162 7.583333333 8.906666667 0.232053463 Up 0.363232916 Llph "LLP homolog, long-term synaptic facilitation (Aplysia)" K02910|1|2e-09|65.9|tup:106734211|large subunit ribosomal protein L31e - - - gi|21313566|ref|NP_079707.1|/4.69345e-46/protein LLP homolog [Mus musculus] 68837 5032 10.08 8.636666667 -0.222949124 Down 0.36309188 Foxk2 forkhead box K2 K09404|1|0.0|1147|mmu:68837|forkhead box protein K - - - gi|238018071|ref|NP_001074401.2|/0/forkhead box protein K2 [Mus musculus] 73863 566 0.56 1.003333333 0.841302254 Up 0.363035466 4930415O20Rik RIKEN cDNA 4930415O20 gene - - - - gi|318043086|ref|NP_001188251.1|/3.06662e-73/uncharacterized protein LOC73863 [Mus musculus] 66209 3221 4.163333333 3.333333333 -0.320773477 Down 0.363035466 Inip INTS3 and NABP interacting protein - GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0006259//DNA metabolic process;GO:0009314//response to radiation;GO:0033554//cellular response to stress gi|6841232|gb|AAF28969.1|AF161409_1/3.63022e-43/HSPC291 [Homo sapiens] 22325 5812 3.113333333 3.923333333 0.333619865 Up 0.362922637 Vav2 vav 2 oncogene K05730|1|0.0|1331|ngi:103742820|guanine nucleotide exchange factor VAV - - - - 50760 1654 0.61 1.063333333 0.801712775 Up 0.362828613 Fbxo17 F-box protein 17 K10101|1|1e-163|579|mmu:50760|F-box protein 17 GO:0031461//cullin-RING ubiquitin ligase complex GO:0005515//protein binding GO:0009057//macromolecule catabolic process gi|893562344|ref|NP_001297616.1|/4.74544e-136/F-box only protein 17 isoform 2 [Mus musculus] 56369 924 57.14333333 51.17333333 -0.159192984 Down 0.362734589 Apip APAF1 interacting protein K08964|1|8e-144|511|mmu:56369|methylthioribulose-1-phosphate dehydratase [EC:4.2.1.109] GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0005515//protein binding;GO:0016836//hydro-lyase activity GO:0006915//apoptotic process;GO:0006576//cellular biogenic amine metabolic process;GO:0043408//regulation of MAPK cascade;GO:0043102;GO:0071265 gi|258613873|ref|NP_062709.3|/6.35997e-143/methylthioribulose-1-phosphate dehydratase [Mus musculus] 11461 1935 239.7 265.3933333 0.146902222 Up 0.362602956 Actb "actin, beta" K05692|1|0.0|763|bacu:103015338|actin beta/gamma 1 - - - - 67773 1503 10.03666667 11.64 0.213810851 Up 0.362555944 Kat8 K(lysine) acetyltransferase 8 K11308|1|0.0|881|rno:310194|histone acetyltransferase MYST1 [EC:2.3.1.48] "GO:0044665//MLL1/2 complex;GO:0000123//histone acetyltransferase complex;GO:0000775//chromosome, centromeric region" GO:0042393//histone binding;GO:0010485//H4 histone acetyltransferase activity;GO:0043169//cation binding "GO:0030097//hemopoiesis;GO:0006351//transcription, DNA-templated;GO:0043967//histone H4 acetylation" gi|62821766|ref|NP_001017378.1|/0/histone acetyltransferase KAT8 [Rattus norvegicus] 105440 3266.81 22.24666667 19.59333333 -0.183226328 Down 0.362546542 Kctd9 potassium channel tetramerisation domain containing 9 K01011|1|1e-08|65.1|fch:102052071|thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2];K04257|3|4e-08|63.5|rro:104681159|olfactory receptor - - GO:0051259//protein oligomerization;GO:0051259//protein oligomerization;GO:0051259//protein oligomerization "gi|148704021|gb|EDL35968.1|/0/potassium channel tetramerisation domain containing 9, isoform CRA_d, partial [Mus musculus]" 68972 1186.68 4.516666667 5.49 0.281547703 Up 0.362546542 Tatdn3 TatD DNase domain containing 3 K03424|1|7e-103|376|mmu:68972|TatD DNase family protein [EC:3.1.21.-] - - - gi|568911787|ref|XP_006497266.1|/8.42437e-162/PREDICTED: putative deoxyribonuclease TATDN3 isoform X1 [Mus musculus] 20692 2640.5 257.5033333 232.5366667 -0.147132888 Down 0.362518335 Sparc secreted acidic cysteine rich glycoprotein "K12819|1|3e-15|86.7|dvi:Dvir_GJ26298|pre-mRNA-processing factor SLU7;K08136|2|3e-10|70.1|mze:101473691|sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican)" GO:0031091//platelet alpha granule;GO:0005578//proteinaceous extracellular matrix;GO:0031091//platelet alpha granule;GO:0005578//proteinaceous extracellular matrix GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding GO:0070848//response to growth factor;GO:0001501//skeletal system development;GO:0009611//response to wounding;GO:0007599//hemostasis;GO:0043583//ear development;GO:0008283//cell proliferation;GO:0046683//response to organophosphorus;GO:0006887//exocytosis;GO:0007154//cell communication;GO:0033273//response to vitamin;GO:0010038//response to metal ion;GO:0030323//respiratory tube development;GO:0009628//response to abiotic stimulus;GO:0097305//response to alcohol;GO:0031960//response to corticosteroid;GO:0001775//cell activation;GO:0002237//response to molecule of bacterial origin;GO:0070848//response to growth factor;GO:0001501//skeletal system development;GO:0009611//response to wounding;GO:0007599//hemostasis;GO:0043583//ear development;GO:0008283//cell proliferation;GO:0046683//response to organophosphorus;GO:0006887//exocytosis;GO:0007154//cell communication;GO:0033273//response to vitamin;GO:0010038//response to metal ion;GO:0030323//respiratory tube development;GO:0009628//response to abiotic stimulus;GO:0097305//response to alcohol;GO:0031960//response to corticosteroid;GO:0001775//cell activation;GO:0002237//response to molecule of bacterial origin gi|595763503|ref|NP_001277746.1|/7.09422e-167/SPARC isoform 2 precursor [Mus musculus] 432555 2971 0.463333333 0.883333333 0.930907477 Up 0.362367896 Gm5431 predicted gene 5431 K17072|1|0.0|1094|mmu:432555|interferon gamma inducible protein 47 - GO:0016787//hydrolase activity GO:0006950//response to stress gi|551032827|gb|AGY29630.1|/0/immunity-related GTPase Irgb9-b8 tandem [Mus musculus molossinus] 65255 3286 0.613333333 1.063333333 0.793850658 Up 0.362320885 Asb4 ankyrin repeat and SOCS box-containing 4 K10326|1|0.0|842|mmu:65255|ankyrin repeat and SOCS box protein 4 GO:0031461//cullin-RING ubiquitin ligase complex GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity GO:0001570//vasculogenesis;GO:0016567//protein ubiquitination;GO:0007165//signal transduction gi|17505202|ref|NP_075535.1|/0/ankyrin repeat and SOCS box protein 4 [Mus musculus] 77864 4902 3.72 2.94 -0.339486466 Down 0.362292677 Ypel2 yippee-like 2 (Drosophila) K04371|1|2e-06|58.5|asn:102375250|mitogen-activated protein kinase 1/3 [EC:2.7.11.24] - - - gi|533160359|ref|XP_005394044.1|/3.45802e-88/PREDICTED: protein yippee-like 2 [Chinchilla lanigera] 71177 3071 5.943333333 7.076666667 0.251797668 Up 0.362292677 Asun "asunder, spermatogenesis regulator" - - - GO:0000087//mitotic M phase gi|133922586|ref|NP_620096.2|/0/protein asunder homolog [Mus musculus] 14359 2283.73 50.75666667 56.60666667 0.157374645 Up 0.362273873 Fxr1 "fragile X mental retardation gene 1, autosomal homolog" K15516|1|0.0|1110|ocu:100340080|fragile X mental retardation protein GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0030529//intracellular ribonucleoprotein complex GO:0003729//mRNA binding GO:0006412//translation;GO:0048869//cellular developmental process;GO:0048513//animal organ development gi|655853589|ref|XP_002716492.2|/0/PREDICTED: fragile X mental retardation syndrome-related protein 1 isoform X4 [Oryctolagus cuniculus] 19378 2264 1.863333333 1.303333333 -0.515679676 Down 0.36226447 Aldh1a2 "aldehyde dehydrogenase family 1, subfamily A2" K07249|1|0.0|1039|mmu:19378|retinal dehydrogenase [EC:1.2.1.36] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0005501//retinoid binding" GO:0021536//diencephalon development;GO:0010467//gene expression;GO:0043010//camera-type eye development;GO:0001935//endothelial cell proliferation;GO:0032526//response to retinoic acid;GO:0001944//vasculature development;GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0030326//embryonic limb morphogenesis;GO:0003002//regionalization;GO:0014031//mesenchymal cell development;GO:0002138//retinoic acid biosynthetic process;GO:0003143//embryonic heart tube morphogenesis;GO:0033273//response to vitamin;GO:0030323//respiratory tube development;GO:0048565//digestive tract development;GO:0030522//intracellular receptor signaling pathway;GO:0009799//specification of symmetry;GO:0048799 gi|225735569|ref|NP_033048.2|/0/retinal dehydrogenase 2 [Mus musculus] 57434 3230 1.853333333 1.293333333 -0.519028231 Down 0.36226447 Xrcc2 X-ray repair complementing defective repair in Chinese hamster cells 2 K10879|1|1e-148|530|mmu:57434|DNA-repair protein XRCC2 GO:0043231//intracellular membrane-bounded organelle "GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled" GO:0006259//DNA metabolic process;GO:0010212//response to ionizing radiation;GO:0033554//cellular response to stress;GO:0043009//chordate embryonic development;GO:0010720//positive regulation of cell development;GO:0043066//negative regulation of apoptotic process gi|31543969|ref|NP_065595.2|/1.21458e-147/DNA repair protein XRCC2 [Mus musculus] 71059 1899 0.673333333 1.136666667 0.755416446 Up 0.362236263 Hexim2 hexamethylene bis-acetamide inducible 2 K15189|1|2e-170|601|mmu:71059|protein HEXIM1/2 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0003723//RNA binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0003723//RNA binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006366//transcription from RNA polymerase II promoter;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006366//transcription from RNA polymerase II promoter;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006366//transcription from RNA polymerase II promoter gi|110625829|ref|NP_081934.1|/1.75943e-169/protein HEXIM2 [Mus musculus] 320709 2781 3.783333333 4.67 0.303764658 Up 0.362236263 Tmem117 transmembrane protein 117 - GO:0031224//intrinsic component of membrane - - gi|30520273|ref|NP_848904.1|/0/transmembrane protein 117 [Mus musculus] 26903 6655.49 22.94333333 20.31 -0.17588477 Down 0.362208056 Dysf dysferlin K18261|1|0.0|4093|mmu:26903|dysferlin - - - gi|118026931|ref|NP_001071162.1|/0/dysferlin isoform 2 [Mus musculus] 216881 2761 4.49 3.633333333 -0.305421716 Down 0.362208056 Wscd1 WSC domain containing 1 K00771|1|5e-12|76.3|mde:101891944|protein xylosyltransferase [EC:2.4.2.26] GO:0031224//intrinsic component of membrane "GO:0016782//transferase activity, transferring sulfur-containing groups" - "gi|148680704|gb|EDL12651.1|/0/cDNA sequence BC030477, isoform CRA_b, partial [Mus musculus]" 18590 1019 10.36 11.95 0.205986615 Up 0.362132837 Pdgfa "platelet derived growth factor, alpha" K04359|1|9e-99|362|mmu:18590|platelet-derived growth factor subunit A GO:0042995//cell projection;GO:0044421 GO:0042802//identical protein binding;GO:0019838//growth factor binding;GO:0046983//protein dimerization activity;GO:0070851//growth factor receptor binding GO:0010543//regulation of platelet activation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043405//regulation of MAP kinase activity;GO:0007010//cytoskeleton organization;GO:0008284//positive regulation of cell proliferation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0060684//epithelial-mesenchymal cell signaling;GO:0022607//cellular component assembly;GO:1900238;GO:0043410//positive regulation of MAPK cascade;GO:0008544//epidermis development;GO:0072110//glomerular mesangial cell proliferation;GO:0001934//positive regulation of protein phosphorylation;GO:0006935//chemotaxis;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0043627//response to estrogen;GO:0006260//DNA replication;GO:0014909//smooth muscle cell migration;GO:0043583//ear development;GO:0030324//lung development;GO:0051052//regulation of DNA metabolic process gi|6715566|ref|NP_032834.1|/7.37602e-98/platelet-derived growth factor subunit A precursor [Mus musculus] 60595 3859 54.66 48.85 -0.162126898 Down 0.362123435 Actn4 actinin alpha 4 K05699|1|0.0|1798|mmu:60595|actinin alpha GO:0031988//membrane-bounded vesicle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0031674//I band;GO:0042995//cell projection;GO:0032432//actin filament bundle GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0003779//actin binding;GO:0036094//small molecule binding GO:0006907//pinocytosis;GO:0007015//actin filament organization;GO:0006915//apoptotic process;GO:0045184//establishment of protein localization;GO:0006928//movement of cell or subcellular component gi|11230802|ref|NP_068695.1|/0/alpha-actinin-4 [Mus musculus] 19344 3180 50.68 56.47666667 0.156238417 Up 0.362114032 Rab5b "RAB5B, member RAS oncogene family" K07888|1|5e-117|425|oas:101112211|Ras-related protein Rab-5B GO:0016020//membrane;GO:0048770;GO:0005769//early endosome GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity GO:0006996//organelle organization;GO:0006897//endocytosis;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction "gi|25304086|gb|AAH40143.1|/2.34298e-119/RAB5B protein, partial [Homo sapiens]" 110854 2577 28.72666667 32.25666667 0.167206764 Up 0.362114032 Ppp2r4 protein phosphatase 2 protein activator K17605|1|4e-177|586|tup:102485909|serine/threonine-protein phosphatase 2A activator GO:0031981//nuclear lumen;GO:0034703//cation channel complex GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0072542//protein phosphatase activator activity;GO:0042802//identical protein binding;GO:0019903//protein phosphatase binding GO:0006915//apoptotic process;GO:0009154//purine ribonucleotide catabolic process;GO:0010923//negative regulation of phosphatase activity;GO:0006470//protein dephosphorylation;GO:0010922//positive regulation of phosphatase activity "gi|148676526|gb|EDL08473.1|/7.35422e-177/protein phosphatase 2A, regulatory subunit B (PR 53), isoform CRA_b, partial [Mus musculus]" 70240 996 7.416666667 8.716666667 0.23300561 Up 0.362095227 Ufsp1 UFM1-specific peptidase 1 K01376|1|8e-44|179|isc:IscW_ISCW014202|UFM1-specific protease 2 [EC:3.4.22.-] - "GO:0016788//hydrolase activity, acting on ester bonds;GO:0019783//ubiquitin-like protein-specific protease activity" GO:0019538//protein metabolic process gi|13899211|ref|NP_081632.1|/2.26064e-120/ufm1-specific protease 1 [Mus musculus] 11797 3333 4.983333333 5.993333333 0.266247536 Up 0.36206702 Birc2 baculoviral IAP repeat-containing 2 K16060|1|0.0|1189|mmu:11797|baculoviral IAP repeat-containing protein 2/3 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0044444//cytoplasmic part;GO:0000803//sex chromosome;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0044444//cytoplasmic part;GO:0000803//sex chromosome GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0019787//ubiquitin-like protein transferase activity "GO:0010556;GO:0006351//transcription, DNA-templated;GO:0097300//programmed necrotic cell death;GO:0008283//cell proliferation;GO:0046683//response to organophosphorus;GO:0006915//apoptotic process;GO:0022411;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0002224//toll-like receptor signaling pathway;GO:0051259//protein oligomerization;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0016567//protein ubiquitination;GO:0052548//regulation of endopeptidase activity;GO:0030154//cell differentiation;GO:0006954//inflammatory response;GO:0097305//response to alcohol;GO:0044767//single-organism developmental process;GO:0009719;GO:0039529//RIG-I signaling pathway;GO:0007049//cell cycle;GO:0010556;GO:0006351//transcription, DNA-templated;GO:0097300//programmed necrotic cell death;GO:0008283//cell proliferation;GO:0046683//response to organophosphorus;GO:0006915//apoptotic process;GO:0022411;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0002224//toll-like receptor signaling pathway;GO:0051259//protein oligomerization;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0016567//protein ubiquitination;GO:0052548//regulation of endopeptidase activity;GO:0030154//cell differentiation;GO:0006954//inflammatory response;GO:0097305//response to alcohol;GO:0044767//single-organism developmental process;GO:0009719;GO:0039529//RIG-I signaling pathway;GO:0007049//cell cycle" gi|160333366|ref|NP_031491.2|/0/baculoviral IAP repeat-containing protein 2 [Mus musculus] 15284 2171 8.506666667 9.923333333 0.222230892 Up 0.362057618 Hlx H2.0-like homeobox K09339|1|0.0|695|mmu:15284|homeobox protein HLX1 - GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0014706//striated muscle tissue development;GO:0035265//organ growth;GO:0045064//T-helper 2 cell differentiation;GO:0008283//cell proliferation;GO:0045063//T-helper 1 cell differentiation;GO:0048483//autonomic nervous system development;GO:0048546//digestive tract morphogenesis" gi|6680225|ref|NP_032276.1|/0/H2.0-like homeobox protein [Mus musculus] 66357 1081 27.31666667 30.83666667 0.174865375 Up 0.362020008 Ostc oligosaccharyltransferase complex subunit (non-catalytic) - GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane GO:0004576//oligosaccharyl transferase activity GO:0006487//protein N-linked glycosylation gi|26378096|dbj|BAB28595.2|/1.34185e-84/unnamed protein product [Mus musculus] 227210 2940 7.836666667 6.64 -0.239056892 Down 0.36190718 Ccnyl1 cyclin Y-like 1 "K18468|1|1e-58|231|rro:104674309|vacuolar protein sorting-associated protein 35;K12491|3|9e-27|125|nle:100586848|Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3" - - GO:0051726//regulation of cell cycle gi|672065395|ref|XP_008765387.1|/1.3677e-174/PREDICTED: cyclin-Y-like protein 1 isoform X3 [Rattus norvegicus] 15896 1308 19.54333333 22.15333333 0.180847236 Up 0.361860168 Icam2 intercellular adhesion molecule 2 K06523|1|4e-148|526|mmu:15896|intercellular adhesion molecule 2 - - - - 14151 2901 54.34333333 48.65666667 -0.159465572 Down 0.361662718 Fech ferrochelatase K01772|1|0.0|798|mmu:14151|ferrochelatase [EC:4.99.1.1] GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0046914//transition metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0046906//tetrapyrrole binding;GO:0016829//lyase activity;GO:0003729//mRNA binding GO:0016125//sterol metabolic process;GO:0034377//plasma lipoprotein particle assembly;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0055080//cation homeostasis;GO:0009411//response to UV;GO:0001932//regulation of protein phosphorylation;GO:0030099//myeloid cell differentiation;GO:0042541//hemoglobin biosynthetic process "gi|20452466|ref|NP_032024.2|/0/ferrochelatase, mitochondrial [Mus musculus] " 66193 1554 9.953333333 11.53666667 0.212974776 Up 0.361634511 Pithd1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 - - - - - 231134 2483 10.32333333 11.90333333 0.205456751 Up 0.361634511 Dok7 docking protein 7 - - - - - 104215 4159 30.73333333 27.25666667 -0.17319511 Down 0.361634511 Rhoq ras homolog family member Q "K07194|1|4e-121|439|pon:100438074|Ras homolog gene family, member Q" GO:0015629//actin cytoskeleton;GO:0044425;GO:0044444//cytoplasmic part GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0019904//protein domain specific binding GO:0032868//response to insulin;GO:0010829//negative regulation of glucose transport;GO:0010828//positive regulation of glucose transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0051129;GO:0031346//positive regulation of cell projection organization;GO:0009154//purine ribonucleotide catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0006366//transcription from RNA polymerase II promoter;GO:0022604//regulation of cell morphogenesis;GO:0030036//actin cytoskeleton organization "gi|148706671|gb|EDL38618.1|/1.23918e-131/ras homolog gene family, member Q, partial [Mus musculus]" 66590 1846 12.31666667 14.13 0.198149602 Up 0.361625108 Farsa "phenylalanyl-tRNA synthetase, alpha subunit" K01889|1|0.0|967|mmu:66590|phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] GO:0044424 GO:0003723//RNA binding;GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation "gi|148679016|gb|EDL10963.1|/0/phenylalanine-tRNA synthetase-like, alpha subunit, isoform CRA_a, partial [Mus musculus]" 319157 358 0.01 0.22 4.459431619 Up 0.361559291 Hist1h4f "histone cluster 1, H4f" K11254|1|6e-41|167|cge:100755357|histone H4 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|444523279|gb|ELV13502.1|/1.59383e-40/histone H2B type 1-M [Tupaia chinensis] 15254 576 185.0866667 205.4 0.150235212 Up 0.361502877 Hint1 histidine triad nucleotide binding protein 1 K02503|1|1e-64|247|rno:690660|histidine triad (HIT) family protein GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043232 GO:0019901//protein kinase binding;GO:0036094//small molecule binding;GO:0003824//catalytic activity "GO:0006351//transcription, DNA-templated;GO:0072331//signal transduction by p53 class mediator;GO:0006195//purine nucleotide catabolic process" "gi|625191146|ref|XP_007638330.1|/5.92385e-71/PREDICTED: histidine triad nucleotide-binding protein 1 isoform X1, partial [Cricetulus griseus]" 11554 2491 5.916666667 7.033333333 0.249423974 Up 0.361371244 Adrb1 "adrenergic receptor, beta 1" K04141|1|0.0|660|mmu:11554|adrenergic receptor beta-1 - - - - 230085 3410 1.41 0.913333333 -0.62648177 Down 0.361258415 Phf24 PHD finger protein 24 - - GO:0046872//metal ion binding - gi|27369996|ref|NP_766278.1|/1.37244e-173/PHD finger protein 24 [Mus musculus] 16835 4546.21 1.75 2.373333333 0.439559818 Up 0.361183196 Ldlr low density lipoprotein receptor K12473|1|0.0|1767|mmu:16835|low-density lipoprotein receptor GO:0000323//lytic vacuole;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0034358//plasma lipoprotein particle;GO:0012505//endomembrane system;GO:0044459;GO:0010008//endosome membrane;GO:0000323//lytic vacuole;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0034358//plasma lipoprotein particle;GO:0012505//endomembrane system;GO:0044459;GO:0010008//endosome membrane;GO:0000323//lytic vacuole;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0034358//plasma lipoprotein particle;GO:0012505//endomembrane system;GO:0044459;GO:0010008//endosome membrane GO:0005515//protein binding;GO:0030228//lipoprotein particle receptor activity;GO:0046872//metal ion binding;GO:0071813//lipoprotein particle binding;GO:0005515//protein binding;GO:0030228//lipoprotein particle receptor activity;GO:0046872//metal ion binding;GO:0071813//lipoprotein particle binding;GO:0005515//protein binding;GO:0030228//lipoprotein particle receptor activity;GO:0046872//metal ion binding;GO:0071813//lipoprotein particle binding GO:0016125//sterol metabolic process;GO:0034381//plasma lipoprotein particle clearance;GO:0043627//response to estrogen;GO:0016192//vesicle-mediated transport;GO:0043434//response to peptide hormone;GO:0033238;GO:0030301//cholesterol transport;GO:0030163//protein catabolic process;GO:0044767//single-organism developmental process;GO:0010866//regulation of triglyceride biosynthetic process;GO:0055092//sterol homeostasis;GO:0016125//sterol metabolic process;GO:0034381//plasma lipoprotein particle clearance;GO:0043627//response to estrogen;GO:0016192//vesicle-mediated transport;GO:0043434//response to peptide hormone;GO:0033238;GO:0030301//cholesterol transport;GO:0030163//protein catabolic process;GO:0044767//single-organism developmental process;GO:0010866//regulation of triglyceride biosynthetic process;GO:0055092//sterol homeostasis;GO:0016125//sterol metabolic process;GO:0034381//plasma lipoprotein particle clearance;GO:0043627//response to estrogen;GO:0016192//vesicle-mediated transport;GO:0043434//response to peptide hormone;GO:0033238;GO:0030301//cholesterol transport;GO:0030163//protein catabolic process;GO:0044767//single-organism developmental process;GO:0010866//regulation of triglyceride biosynthetic process;GO:0055092//sterol homeostasis gi|358030304|ref|NP_001239588.1|/0/low-density lipoprotein receptor isoform 3 presursor precursor [Mus musculus] 76073 1509 14.81666667 16.90333333 0.190086855 Up 0.361173794 Pcgf5 polycomb group ring finger 5 K11489|1|1e-123|445|mmu:76073|polycomb group RING finger protein 5 GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" "gi|148709823|gb|EDL41769.1|/3.1168e-123/polycomb group ring finger 5, isoform CRA_b, partial [Mus musculus]" 71966 2013 28.1 31.53333333 0.166307552 Up 0.361136184 Nkiras2 NFKB inhibitor interacting Ras-like protein 2 K17197|1|2e-94|349|rno:287707|NF-kappa-B inhibitor-interacting Ras-like protein GO:0044424 GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0009154//purine ribonucleotide catabolic process gi|21312616|ref|NP_082300.1|/1.28391e-93/NF-kappa-B inhibitor-interacting Ras-like protein 2 [Mus musculus] 98660 6227 185.55 166.7733333 -0.153919377 Down 0.361107977 Atp1a2 "ATPase, Na+/K+ transporting, alpha 2 polypeptide" K01539|1|0.0|1962|rno:24212|sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9] GO:0043231//intracellular membrane-bounded organelle;GO:0030425//dendrite;GO:0042383//sarcolemma;GO:0005887//integral component of plasma membrane GO:0032550;GO:0008556//potassium-transporting ATPase activity;GO:0043169//cation binding "GO:0006941//striated muscle contraction;GO:0007626//locomotory behavior;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0006937//regulation of muscle contraction;GO:0008016//regulation of heart contraction;GO:0030001//metal ion transport;GO:0009612//response to mechanical stimulus;GO:0009152//purine ribonucleotide biosynthetic process;GO:0007632//visual behavior;GO:0032970//regulation of actin filament-based process;GO:0042310//vasoconstriction;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0014070//response to organic cyclic compound;GO:0001505//regulation of neurotransmitter levels" gi|6978545|ref|NP_036637.1|/0/sodium/potassium-transporting ATPase subunit alpha-2 precursor [Rattus norvegicus] 107035 4416 7.69 6.5 -0.24254388 Down 0.361089172 Fbxo38 F-box protein 38 K10313|1|0.0|2225|mmu:107035|F-box protein 38 GO:0043231//intracellular membrane-bounded organelle - - gi|160333600|ref|NP_598897.2|/0/F-box only protein 38 [Mus musculus] 233813 4575 4.636666667 3.753333333 -0.304915592 Down 0.361051563 Vwa3a von Willebrand factor A domain containing 3A - - - - gi|117320533|ref|NP_808365.2|/0/von Willebrand factor A domain-containing protein 3A [Mus musculus] 69372 1691 3.87 4.75 0.295593947 Up 0.361051563 Mocs3 molybdenum cofactor synthesis 3 K11996|1|1e-174|615|mmu:69372|adenylyltransferase and sulfurtransferase [EC:2.7.7.80] GO:0044444//cytoplasmic part "GO:0008641//small protein activating enzyme activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016783//sulfurtransferase activity" GO:0018198;GO:0009108//coenzyme biosynthetic process;GO:0002097 gi|237820699|ref|NP_001153802.1|/1.00713e-173/adenylyltransferase and sulfurtransferase MOCS3 [Mus musculus] 70785 2539 0.523333333 0.95 0.86019736 Up 0.360985746 Dennd1c DENN/MADD domain containing 1C K20160|1|0.0|1456|mmu:70785|DENN domain-containing protein 1 GO:0031982//vesicle;GO:0044424 GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0019222//regulation of metabolic process gi|24025656|ref|NP_705779.1|/0/DENN domain-containing protein 1C [Mus musculus] 69234 1033 1.973333333 2.63 0.414428124 Up 0.360957539 Zfp688 zinc finger protein 688 K09228|1|3e-152|540|mmu:69234|KRAB domain-containing zinc finger protein - GO:0046872//metal ion binding - gi|306035204|ref|NP_081275.3|/2.64668e-151/zinc finger protein 688 [Mus musculus] 94192 2084 1.02 0.583333333 -0.806176731 Down 0.360929332 C1galt1 "core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1" K00731|1|0.0|769|mmu:94192|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122] GO:0031224//intrinsic component of membrane "GO:0043169//cation binding;GO:0048531//beta-1,3-galactosyltransferase activity" GO:0048646//anatomical structure formation involved in morphogenesis;GO:0016266//O-glycan processing;GO:0044767//single-organism developmental process;GO:0048869//cellular developmental process gi|282396086|ref|NP_443719.3|/0/glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 [Mus musculus] 81909 1235 14.47666667 16.56 0.193973221 Up 0.360872917 Zfpl1 zinc finger like protein 1 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0006810//transport;GO:0006351//transcription, DNA-templated" gi|13195658|ref|NP_077193.1|/1.32531e-142/zinc finger protein-like 1 [Mus musculus] 15042 2182 9.9 8.5 -0.219965684 Down 0.360863515 H2-T24 "histocompatibility 2, T region locus 24" "K06751|1|0.0|771|mmu:15042|major histocompatibility complex, class I" GO:0042611;GO:0031224//intrinsic component of membrane - GO:0002376//immune system process "gi|144953909|ref|NP_032233.2|/0/histocompatibility 2, T region locus 24 precursor [Mus musculus] " 193740 2798 2.21 1.606666667 -0.459975724 Down 0.360807101 Hspa1a heat shock protein 1A K03283|1|0.0|1132|mmu:193740|heat shock 70kDa protein 1/8 GO:0016234//inclusion body;GO:0016604//nuclear body;GO:0043234//protein complex;GO:0044459;GO:0044429 GO:0032550;GO:0044389//ubiquitin-like protein ligase binding;GO:0008134//transcription factor binding GO:0009605//response to external stimulus;GO:0006457//protein folding;GO:0006401//RNA catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0035966//response to topologically incorrect protein;GO:0008283//cell proliferation;GO:0019229//regulation of vasoconstriction;GO:0006259//DNA metabolic process;GO:0035036//sperm-egg recognition;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0030218//erythrocyte differentiation;GO:0016049//cell growth;GO:0051129 gi|124339829|ref|NP_034609.2|/0/heat shock 70 kDa protein 1A [Mus musculus] 170625 4466 6.326666667 5.286666667 -0.259087221 Down 0.360788296 Snx18 sorting nexin 18 K17923|1|0.0|1032|mmu:170625|sorting nexin-9/18/33 GO:0043005//neuron projection;GO:0030135//coated vesicle;GO:0044297//cell body;GO:0031090//organelle membrane;GO:0009898//cytoplasmic side of plasma membrane GO:0005543//phospholipid binding GO:0043087//regulation of GTPase activity;GO:0044763;GO:0016192//vesicle-mediated transport;GO:0045184//establishment of protein localization "gi|148686440|gb|EDL18387.1|/0/sorting nexin associated golgi protein 1, partial [Mus musculus]" 545056 1189 9.78 11.33666667 0.213090135 Up 0.360750686 Gm5801 "ubiquitin-conjugating enzyme E2, J2 homolog pseudogene" K04554|1|4e-135|483|rno:298689|ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0019787//ubiquitin-like protein transferase activity;GO:0032550 GO:0035966//response to topologically incorrect protein;GO:0032446//protein modification by small protein conjugation gi|537231821|gb|ERE84253.1|/2.40362e-149/ubiquitin-conjugating enzyme E2 J2-like isoform 1 [Cricetulus griseus] 225341 1688 176.23 158.45 -0.153431878 Down 0.360731882 Lims2 LIM and senescent cell antigen like domains 2 K05760|1|1e-36|157|cbr:CBG09041|paxillin - - - - 67588 4272.27 4.136666667 5.05 0.287814678 Up 0.360675467 Rnf41 ring finger protein 41 K11981|1|0.0|653|ngi:103746509|E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0005126//cytokine receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0005126//cytokine receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0005126//cytokine receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0005126//cytokine receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0005126//cytokine receptor binding;GO:0019787//ubiquitin-like protein transferase activity GO:0016477//cell migration;GO:0012502//induction of programmed cell death;GO:0030098//lymphocyte differentiation;GO:0002682//regulation of immune system process;GO:0031323//regulation of cellular metabolic process;GO:0016567//protein ubiquitination;GO:0008283//cell proliferation;GO:0000165//MAPK cascade;GO:0016477//cell migration;GO:0012502//induction of programmed cell death;GO:0030098//lymphocyte differentiation;GO:0002682//regulation of immune system process;GO:0031323//regulation of cellular metabolic process;GO:0016567//protein ubiquitination;GO:0008283//cell proliferation;GO:0000165//MAPK cascade;GO:0016477//cell migration;GO:0012502//induction of programmed cell death;GO:0030098//lymphocyte differentiation;GO:0002682//regulation of immune system process;GO:0031323//regulation of cellular metabolic process;GO:0016567//protein ubiquitination;GO:0008283//cell proliferation;GO:0000165//MAPK cascade;GO:0016477//cell migration;GO:0012502//induction of programmed cell death;GO:0030098//lymphocyte differentiation;GO:0002682//regulation of immune system process;GO:0031323//regulation of cellular metabolic process;GO:0016567//protein ubiquitination;GO:0008283//cell proliferation;GO:0000165//MAPK cascade;GO:0016477//cell migration;GO:0012502//induction of programmed cell death;GO:0030098//lymphocyte differentiation;GO:0002682//regulation of immune system process;GO:0031323//regulation of cellular metabolic process;GO:0016567//protein ubiquitination;GO:0008283//cell proliferation;GO:0000165//MAPK cascade gi|821037916|ref|XP_012359607.1|/2.02598e-121/PREDICTED: E3 ubiquitin-protein ligase NRDP1 isoform X2 [Nomascus leucogenys] 21827 3205 3.14 2.433333333 -0.367830596 Down 0.360496822 Thbs3 thrombospondin 3 K04659|1|0.0|1809|mmu:21827|thrombospondin 2/3/4/5 GO:0044444//cytoplasmic part GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding GO:0003416//endochondral bone growth;GO:0031589//cell-substrate adhesion;GO:0001503//ossification gi|239915968|ref|NP_038719.2|/0/thrombospondin-3 precursor [Mus musculus] 52570 1419 4.49 5.44 0.276891207 Up 0.360478017 Ccdc69 coiled-coil domain containing 69 - - - - gi|115270981|ref|NP_803422.2|/2.77089e-110/coiled-coil domain-containing protein 69 [Mus musculus] 55934 1142 46.82333333 52.21 0.157098516 Up 0.360440408 Rp9 retinitis pigmentosa 9 (human) K19604|1|8e-86|319|mmu:55934|retinitis pigmentosa 9 protein GO:0030867//rough endoplasmic reticulum membrane;GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0006396//RNA processing gi|74222240|dbj|BAE26927.1|/1.11992e-102/unnamed protein product [Mus musculus] 11602 1530 0.01 0.216666667 4.437405312 Up 0.360393396 Angpt4 angiopoietin 4 K05467|1|0.0|917|mmu:11602|angiopoietin 4 GO:0044421 GO:0030296//protein tyrosine kinase activator activity;GO:0005126//cytokine receptor binding GO:0001934//positive regulation of protein phosphorylation;GO:0001525//angiogenesis;GO:0009888//tissue development;GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010596//negative regulation of endothelial cell migration;GO:0010595//positive regulation of endothelial cell migration gi|6753006|ref|NP_033771.1|/0/angiopoietin-4 precursor [Mus musculus] 66121 619 45.47333333 50.84 0.160943268 Up 0.360308774 Chchd1 coiled-coil-helix-coiled-coil-helix domain containing 1 - GO:0031981//nuclear lumen GO:0005488//binding - gi|13384734|ref|NP_079642.1|/6.86924e-62/coiled-coil-helix-coiled-coil-helix domain-containing protein 1 [Mus musculus] 100504601 2384 8.616666667 10.00666667 0.215759696 Up 0.360280567 Gm16702 "predicted gene, 16702" - - - - - 20778 2497.59 18.77666667 21.3 0.18191246 Up 0.36025236 Scarb1 "scavenger receptor class B, member 1" "K13885|1|0.0|900|mmu:20778|scavenger receptor class B, member 1" - - - - 52815 2235 18.68666667 21.20666667 0.182508628 Up 0.36025236 Ldhd lactate dehydrogenase D K00102|1|0.0|978|mmu:52815|D-lactate dehydrogenase (cytochrome) [EC:1.1.2.4] GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane "GO:0004457//lactate dehydrogenase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding" GO:0009152//purine ribonucleotide biosynthetic process "gi|34328379|ref|NP_081846.3|/0/probable D-lactate dehydrogenase, mitochondrial [Mus musculus]" 20608 1388 0.583333333 0.233333333 -1.321928095 Down 0.360073715 Sstr4 somatostatin receptor 4 K04220|1|0.0|763|mmu:20608|somatostatin receptor 4 GO:0044424;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0008188//neuropeptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0001676//long-chain fatty acid metabolic process;GO:0009755//hormone-mediated signaling pathway;GO:0048870//cell motility;GO:0051384//response to glucocorticoid;GO:0046058//cAMP metabolic process;GO:0007420//brain development;GO:0000165//MAPK cascade gi|49169818|ref|NP_033245.2|/0/somatostatin receptor type 4 [Mus musculus] 66913 1870 14.34333333 16.39666667 0.193022215 Up 0.360026703 Kdelr2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 K10949|1|9e-118|426|lve:103075684|ER lumen protein retaining receptor GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046923//ER retention sequence binding GO:0035437//maintenance of protein localization in endoplasmic reticulum;GO:0015031//protein transport gi|13385318|ref|NP_080117.1|/7.55528e-117/ER lumen protein-retaining receptor 2 [Mus musculus] 66559 1259 14.3 16.34666667 0.192981331 Up 0.360026703 Metap1d methionyl aminopeptidase type 1D (mitochondrial) K01265|1|7e-177|622|mmu:66559|methionyl aminopeptidase [EC:3.4.11.18] GO:0043231//intracellular membrane-bounded organelle GO:0008237//metallopeptidase activity;GO:0043169//cation binding GO:0019538//protein metabolic process "gi|17975502|ref|NP_079909.1|/5.45603e-176/methionine aminopeptidase 1D, mitochondrial precursor [Mus musculus]" 319953 2074 44.53 49.81 0.161657799 Up 0.360007898 Ttll1 tubulin tyrosine ligase-like 1 K16599|1|0.0|878|mmu:319953|tubulin polyglutamylase TTLL1 [EC:6.-.-.-] GO:0015630//microtubule cytoskeleton GO:0032550;GO:0016881//acid-amino acid ligase activity GO:0048858//cell projection morphogenesis;GO:0003341//cilium movement;GO:0018200//peptidyl-glutamic acid modification gi|188219535|ref|NP_849200.2|/0/probable tubulin polyglutamylase TTLL1 [Mus musculus] 64384 1438.6 29.29 25.98 -0.173006762 Down 0.359932679 Sirt3 sirtuin 3 K11413|1|5e-146|520|mmu:64384|NAD-dependent deacetylase sirtuin 3 [EC:3.5.1.-] GO:0005739//mitochondrion;GO:0005739//mitochondrion;GO:0044429 "GO:0043168//anion binding;GO:0016763//transferase activity, transferring pentosyl groups;GO:0046914//transition metal ion binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0000166//nucleotide binding;GO:0043168//anion binding;GO:0016763//transferase activity, transferring pentosyl groups;GO:0046914//transition metal ion binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0000166//nucleotide binding;GO:0043168//anion binding;GO:0016763//transferase activity, transferring pentosyl groups;GO:0046914//transition metal ion binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0000166//nucleotide binding" GO:0006476//protein deacetylation;GO:0045333//cellular respiration;GO:0006486//protein glycosylation;GO:0006476//protein deacetylation;GO:0045333//cellular respiration;GO:0006486//protein glycosylation;GO:0006476//protein deacetylation;GO:0045333//cellular respiration;GO:0006486//protein glycosylation gi|295317388|ref|NP_001171275.1|/4.58065e-145/NAD-dependent protein deacetylase sirtuin-3 isoform 3 [Mus musculus] 338367 5353 4.64 3.773333333 -0.298285253 Down 0.359866862 Myo1d myosin ID K10356|1|0.0|1993|mmu:338367|myosin I GO:0032589//neuron projection membrane;GO:0015629//actin cytoskeleton;GO:0005783//endoplasmic reticulum "GO:0008092//cytoskeletal protein binding;GO:0032550;GO:0042623//ATPase activity, coupled;GO:0003774//motor activity" GO:0010921//regulation of phosphatase activity gi|118026911|ref|NP_796364.2|/0/unconventional myosin-Id [Mus musculus] 13829 3952 3.813333333 4.683333333 0.296483078 Up 0.359866862 Dmtn dematin actin binding protein K14411|1|8e-78|295|ocu:100342991|RNA-binding protein Musashi;K07520|2|6e-51|206|cmy:102929752|actin-binding LIM protein GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0005856//cytoskeleton;GO:0005856//cytoskeleton;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0007015//actin filament organization;GO:0030835//negative regulation of actin filament depolymerization;GO:0030835//negative regulation of actin filament depolymerization;GO:0030835//negative regulation of actin filament depolymerization;GO:0030835//negative regulation of actin filament depolymerization;GO:0030835//negative regulation of actin filament depolymerization gi|358030320|ref|NP_001239594.1|/1.04069e-156/dematin isoform 4 [Mus musculus] 22021 2013.68 8.566666667 9.946666667 0.215479176 Up 0.359791643 Tpst1 protein-tyrosine sulfotransferase 1 K01021|1|0.0|754|mmu:22021|protein-tyrosine sulfotransferase [EC:2.8.2.20] GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane GO:0008146//sulfotransferase activity;GO:0008146//sulfotransferase activity GO:0006952//defense response;GO:0006477//protein sulfation;GO:0006952//defense response;GO:0006477//protein sulfation gi|7305591|ref|NP_038865.1|/0/protein-tyrosine sulfotransferase 1 [Mus musculus] 20597 2430 143.2533333 158.73 0.148006114 Up 0.359782241 Smpd1 "sphingomyelin phosphodiesterase 1, acid lysosomal" K12350|1|0.0|1249|mmu:20597|sphingomyelin phosphodiesterase [EC:3.1.4.12] GO:0030141//secretory granule;GO:0000323//lytic vacuole;GO:0044421 GO:0004620//phospholipase activity GO:0009968//negative regulation of signal transduction;GO:0006915//apoptotic process;GO:0014070//response to organic cyclic compound;GO:0043405//regulation of MAP kinase activity;GO:0006470//protein dephosphorylation;GO:0006684//sphingomyelin metabolic process gi|6755582|ref|NP_035551.1|/0/sphingomyelin phosphodiesterase precursor [Mus musculus] 20541 18607.3 16.42666667 14.39 -0.190973163 Down 0.359735229 Slc8a1 "solute carrier family 8 (sodium/calcium exchanger), member 1" K05849|1|0.0|1760|mmu:20541|solute carrier family 8 (sodium/calcium exchanger) GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0042383//sarcolemma;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0031674//I band;GO:0015630//microtubule cytoskeleton;GO:0044291//cell-cell contact zone;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0042383//sarcolemma;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0031674//I band;GO:0015630//microtubule cytoskeleton;GO:0044291//cell-cell contact zone;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0042383//sarcolemma;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0031674//I band;GO:0015630//microtubule cytoskeleton;GO:0044291//cell-cell contact zone;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0042383//sarcolemma;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0031674//I band;GO:0015630//microtubule cytoskeleton;GO:0044291//cell-cell contact zone GO:0015291//secondary active transmembrane transporter activity;GO:0008092//cytoskeletal protein binding;GO:0015081//sodium ion transmembrane transporter activity;GO:0043169//cation binding;GO:0015291//secondary active transmembrane transporter activity;GO:0008092//cytoskeletal protein binding;GO:0015081//sodium ion transmembrane transporter activity;GO:0043169//cation binding;GO:0015291//secondary active transmembrane transporter activity;GO:0008092//cytoskeletal protein binding;GO:0015081//sodium ion transmembrane transporter activity;GO:0043169//cation binding;GO:0015291//secondary active transmembrane transporter activity;GO:0008092//cytoskeletal protein binding;GO:0015081//sodium ion transmembrane transporter activity;GO:0043169//cation binding GO:0001701//in utero embryonic development;GO:0035725//sodium ion transmembrane transport;GO:0010761//fibroblast migration;GO:0010644//cell communication by electrical coupling;GO:0008016//regulation of heart contraction;GO:0030900//forebrain development;GO:0031667//response to nutrient levels;GO:0055002//striated muscle cell development;GO:0090075//relaxation of muscle;GO:0006941//striated muscle contraction;GO:0031000//response to caffeine;GO:0000302//response to reactive oxygen species;GO:0006939//smooth muscle contraction;GO:0051591//response to cAMP;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0009746;GO:0070588//calcium ion transmembrane transport;GO:0009887//organ morphogenesis;GO:0001701//in utero embryonic development;GO:0035725//sodium ion transmembrane transport;GO:0010761//fibroblast migration;GO:0010644//cell communication by electrical coupling;GO:0008016//regulation of heart contraction;GO:0030900//forebrain development;GO:0031667//response to nutrient levels;GO:0055002//striated muscle cell development;GO:0090075//relaxation of muscle;GO:0006941//striated muscle contraction;GO:0031000//response to caffeine;GO:0000302//response to reactive oxygen species;GO:0006939//smooth muscle contraction;GO:0051591//response to cAMP;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0009746;GO:0070588//calcium ion transmembrane transport;GO:0009887//organ morphogenesis;GO:0001701//in utero embryonic development;GO:0035725//sodium ion transmembrane transport;GO:0010761//fibroblast migration;GO:0010644//cell communication by electrical coupling;GO:0008016//regulation of heart contraction;GO:0030900//forebrain development;GO:0031667//response to nutrient levels;GO:0055002//striated muscle cell development;GO:0090075//relaxation of muscle;GO:0006941//striated muscle contraction;GO:0031000//response to caffeine;GO:0000302//response to reactive oxygen species;GO:0006939//smooth muscle contraction;GO:0051591//response to cAMP;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0009746;GO:0070588//calcium ion transmembrane transport;GO:0009887//organ morphogenesis;GO:0001701//in utero embryonic development;GO:0035725//sodium ion transmembrane transport;GO:0010761//fibroblast migration;GO:0010644//cell communication by electrical coupling;GO:0008016//regulation of heart contraction;GO:0030900//forebrain development;GO:0031667//response to nutrient levels;GO:0055002//striated muscle cell development;GO:0090075//relaxation of muscle;GO:0006941//striated muscle contraction;GO:0031000//response to caffeine;GO:0000302//response to reactive oxygen species;GO:0006939//smooth muscle contraction;GO:0051591//response to cAMP;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0009746;GO:0070588//calcium ion transmembrane transport;GO:0009887//organ morphogenesis gi|88604691|gb|ABD46717.1|/0/solute carrier family 8 sodium/calcium exchanger member 1 splicing variant 1.41 [Mus musculus] 27528 2139.28 5.856666667 6.956666667 0.248316409 Up 0.359678815 Nrep neuronal regeneration related protein - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0007409//axonogenesis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007409//axonogenesis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007409//axonogenesis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007409//axonogenesis;GO:0007179//transforming growth factor beta receptor signaling pathway "gi|148664657|gb|EDK97073.1|/4.71408e-41/DNA segment, human D4S114, isoform CRA_b, partial [Mus musculus]" 13645 4277.43 0.876666667 1.366666667 0.64056111 Up 0.359650607 Egf epidermal growth factor K04357|1|0.0|2463|mmu:13645|epidermal growth factor GO:0016020//membrane;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0044421 GO:0070851//growth factor receptor binding;GO:0046872//metal ion binding;GO:0070851//growth factor receptor binding "GO:0043405//regulation of MAP kinase activity;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032880//regulation of protein localization;GO:0035411//catenin import into nucleus;GO:0006351//transcription, DNA-templated;GO:0031398//positive regulation of protein ubiquitination;GO:0021930//cerebellar granule cell precursor proliferation;GO:0001934//positive regulation of protein phosphorylation;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0034765//regulation of ion transmembrane transport;GO:0051099//positive regulation of binding;GO:0010874//regulation of cholesterol efflux;GO:0009306//protein secretion;GO:0007067//mitotic nuclear division;GO:0060562//epithelial tube morphogenesis;GO:0043405//regulation of MAP kinase activity;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032880//regulation of protein localization;GO:0035411//catenin import into nucleus;GO:0006351//transcription, DNA-templated;GO:0031398//positive regulation of protein ubiquitination;GO:0021930//cerebellar granule cell precursor proliferation;GO:0001934//positive regulation of protein phosphorylation;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0034765//regulation of ion transmembrane transport;GO:0051099//positive regulation of binding;GO:0010874//regulation of cholesterol efflux;GO:0009306//protein secretion;GO:0007067//mitotic nuclear division;GO:0060562//epithelial tube morphogenesis" "gi|148680290|gb|EDL12237.1|/0/epidermal growth factor, isoform CRA_a [Mus musculus]" 71116 2496.19 6.373333333 7.546666667 0.243791435 Up 0.359528376 Stx18 syntaxin 18 K08492|1|4e-151|538|mmu:71116|syntaxin 18 GO:0012505//endomembrane system;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0005515//protein binding GO:0016482//cytosolic transport;GO:0015031//protein transport gi|575501591|ref|NP_001276465.1|/3.32086e-155/syntaxin-18 isoform 3 [Mus musculus] 52637 965 141.3 156.2966667 0.145525545 Up 0.359500169 Cisd1 CDGSH iron sulfur domain 1 - GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding GO:0043467//regulation of generation of precursor metabolites and energy gi|625281399|ref|XP_007632369.1|/2.94788e-53/PREDICTED: CDGSH iron-sulfur domain-containing protein 1 isoform X2 [Cricetulus griseus] 237782 7394 3.44 2.696666667 -0.351231363 Down 0.35946256 Smcr8 "Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)" K17478|1|5e-06|57.8|pps:100993704|FK506-binding protein 15 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - - gi|146198710|ref|NP_001078909.1|/0/Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog isoform 1 [Mus musculus] 74116 2245 49.86 44.70666667 -0.1573929 Down 0.35942495 Pi16 peptidase inhibitor 16 K20412|1|0.0|859|mmu:74116|peptidase inhibitor 16 GO:0031224//intrinsic component of membrane GO:0004857//enzyme inhibitor activity GO:0051346//negative regulation of hydrolase activity gi|116089320|ref|NP_076223.3|/0/peptidase inhibitor 16 precursor [Mus musculus] 20182 2595.69 25.89 29.15333333 0.171265882 Up 0.359415548 Rxrb retinoid X receptor beta K08525|1|0.0|638|rno:361801|retinoid X receptor beta GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0010861//thyroid hormone receptor activator activity;GO:0046983//protein dimerization activity;GO:0046872//metal ion binding;GO:0000975//regulatory region DNA binding;GO:0003708//retinoic acid receptor activity;GO:0008134//transcription factor binding;GO:0010861//thyroid hormone receptor activator activity;GO:0046983//protein dimerization activity;GO:0046872//metal ion binding;GO:0000975//regulatory region DNA binding;GO:0003708//retinoic acid receptor activity;GO:0008134//transcription factor binding;GO:0046914//transition metal ion binding;GO:0010861//thyroid hormone receptor activator activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0003708//retinoic acid receptor activity;GO:0008134//transcription factor binding;GO:0046914//transition metal ion binding;GO:0010861//thyroid hormone receptor activator activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0003708//retinoic acid receptor activity;GO:0008134//transcription factor binding GO:0006366//transcription from RNA polymerase II promoter;GO:0055007//cardiac muscle cell differentiation;GO:0032526//response to retinoic acid;GO:0071310//cellular response to organic substance;GO:0001890//placenta development;GO:0014855;GO:0030522//intracellular receptor signaling pathway;GO:0042552//myelination;GO:0006366//transcription from RNA polymerase II promoter;GO:0055007//cardiac muscle cell differentiation;GO:0032526//response to retinoic acid;GO:0071310//cellular response to organic substance;GO:0001890//placenta development;GO:0014855;GO:0030522//intracellular receptor signaling pathway;GO:0042552//myelination;GO:0006366//transcription from RNA polymerase II promoter;GO:0055007//cardiac muscle cell differentiation;GO:0032526//response to retinoic acid;GO:0009755//hormone-mediated signaling pathway;GO:0001890//placenta development;GO:0014855;GO:0030522//intracellular receptor signaling pathway;GO:0042552//myelination;GO:0006366//transcription from RNA polymerase II promoter;GO:0055007//cardiac muscle cell differentiation;GO:0032526//response to retinoic acid;GO:0009755//hormone-mediated signaling pathway;GO:0001890//placenta development;GO:0043009//chordate embryonic development;GO:0014855;GO:0030522//intracellular receptor signaling pathway;GO:0042552//myelination gi|512969462|ref|XP_004846886.1|/0/PREDICTED: retinoic acid receptor RXR-beta isoform X3 [Heterocephalus glaber] 226744 4568 18.04333333 20.51 0.184861604 Up 0.359396743 Cnst "consortin, connexin sorting protein" K17581|1|0.0|1299|mmu:226744|consortin "GO:0031224//intrinsic component of membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0019899//enzyme binding GO:0042996//regulation of Golgi to plasma membrane protein transport;GO:0010921//regulation of phosphatase activity gi|31559922|ref|NP_666217.2|/0/consortin [Mus musculus] 76454 4372 44.80333333 49.93666667 0.156493451 Up 0.359377938 Fbxo31 F-box protein 31 K10308|1|0.0|842|mmu:76454|F-box protein 31 GO:0031461//cullin-RING ubiquitin ligase complex GO:0005515//protein binding GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044773//mitotic DNA damage checkpoint;GO:0032446//protein modification by small protein conjugation gi|158517904|ref|NP_598526.3|/0/F-box only protein 31 [Mus musculus] 378431 4457 146.86 132.54 -0.148013681 Down 0.359283914 Txlnb taxilin beta K06106|1|4e-23|113|smm:Smp_164620|cortactin - GO:0000149//SNARE binding - "gi|148671529|gb|EDL03476.1|/0/taxilin beta, isoform CRA_a, partial [Mus musculus]" 66935 1945 8.106666667 9.473333333 0.224763326 Up 0.359218098 Cir1 "corepressor interacting with RBPJ, 1" K06066|1|7e-110|400|mmu:66935|CBF1 interacting corepressor GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0016604//nuclear body - "GO:0006396//RNA processing;GO:0006351//transcription, DNA-templated" gi|157042778|ref|NP_080130.2|/6.0625e-109/corepressor interacting with RBPJ 1 [Mus musculus] 30791 2344 42.03333333 47.11333333 0.164601538 Up 0.359208695 Slc39a1 "solute carrier family 39 (zinc transporter), member 1" "K14709|1|1e-144|516|mmu:30791|solute carrier family 39 (zinc transporter), member 1/2/3" GO:0031224//intrinsic component of membrane GO:0046915//transition metal ion transmembrane transporter activity GO:0044763;GO:0006829//zinc II ion transport gi|170295861|ref|NP_038929.2|/1.25105e-143/zinc transporter ZIP1 [Mus musculus] 100126227 924 0.273333333 0.633333333 1.212303604 Up 0.359142879 Gm13031 predicted gene 13031 K01481|1|1e-09|65.9|pale:102894399|protein-arginine deiminase [EC:3.5.3.15] - - - - 213208 2479 1.673333333 1.146666667 -0.545278799 Down 0.359133476 Il20rb interleukin 20 receptor beta K05137|1|6e-179|630|mmu:213208|interleukin 20 receptor beta GO:0031224//intrinsic component of membrane GO:0019955//cytokine binding GO:0001894//tissue homeostasis;GO:0001819//positive regulation of cytokine production;GO:0001818//negative regulation of cytokine production;GO:0042098//T cell proliferation;GO:0001806//type IV hypersensitivity;GO:0002764//immune response-regulating signaling pathway gi|158428112|ref|NP_001028715.2|/4.85558e-178/interleukin-20 receptor subunit beta precursor [Mus musculus] 12319 5722 2.65 2 -0.40599236 Down 0.359086464 Car8 carbonic anhydrase 8 K01672|1|3e-151|539|mmu:12319|carbonic anhydrase [EC:4.2.1.1] GO:0044424 GO:0046914//transition metal ion binding;GO:0016836//hydro-lyase activity GO:0048017//inositol lipid-mediated signaling;GO:0044237//cellular metabolic process gi|50287|emb|CAA43668.1|/2.44014e-152/carbonic anhydrase-related polypeptide [Mus musculus] 69981 3680 16.14333333 14.12333333 -0.192857874 Down 0.35906766 Tmem30a transmembrane protein 30A - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0030030//cell projection organization;GO:0033365//protein localization to organelle;GO:0032527//protein exit from endoplasmic reticulum gi|17391158|gb|AAH18491.1|/0/Transmembrane protein 30A [Mus musculus] 227622 997 14.15333333 16.17666667 0.192772489 Up 0.35906766 BC029214 cDNA sequence BC029214 - - - - - 22084 6281.29 46.96333333 41.93 -0.163551981 Down 0.35903005 Tsc2 tuberous sclerosis 2 K07207|1|0.0|3134|rno:24855|tuberous sclerosis 2 GO:0005856//cytoskeleton;GO:0043005//neuron projection;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0005856//cytoskeleton;GO:0043005//neuron projection;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0005856//cytoskeleton;GO:0043005//neuron projection;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044444//cytoplasmic part;GO:0044297//cell body GO:0008047//enzyme activator activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0019899//enzyme binding;GO:0008047//enzyme activator activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0019899//enzyme binding;GO:0008047//enzyme activator activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0019899//enzyme binding GO:0014020;GO:0016055//Wnt signaling pathway;GO:0043405//regulation of MAP kinase activity;GO:0001933//negative regulation of protein phosphorylation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0006935//chemotaxis;GO:0002526//acute inflammatory response;GO:0006886//intracellular protein transport;GO:0007264//small GTPase mediated signal transduction;GO:0006897//endocytosis;GO:0008361//regulation of cell size;GO:0007049//cell cycle;GO:0008285//negative regulation of cell proliferation;GO:0051259//protein oligomerization;GO:0008286//insulin receptor signaling pathway;GO:0014020;GO:0016055//Wnt signaling pathway;GO:0043405//regulation of MAP kinase activity;GO:0001933//negative regulation of protein phosphorylation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0006935//chemotaxis;GO:0002526//acute inflammatory response;GO:0006886//intracellular protein transport;GO:0007264//small GTPase mediated signal transduction;GO:0006897//endocytosis;GO:0008361//regulation of cell size;GO:0007049//cell cycle;GO:0008285//negative regulation of cell proliferation;GO:0051259//protein oligomerization;GO:0008286//insulin receptor signaling pathway;GO:0014020;GO:0016055//Wnt signaling pathway;GO:0043405//regulation of MAP kinase activity;GO:0001933//negative regulation of protein phosphorylation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0006935//chemotaxis;GO:0002526//acute inflammatory response;GO:0006886//intracellular protein transport;GO:0007264//small GTPase mediated signal transduction;GO:0006897//endocytosis;GO:0008361//regulation of cell size;GO:0007049//cell cycle;GO:0008285//negative regulation of cell proliferation;GO:0051259//protein oligomerization;GO:0008286//insulin receptor signaling pathway "gi|148690397|gb|EDL22344.1|/0/tuberous sclerosis 2, isoform CRA_d, partial [Mus musculus]" 121021 8050 6.773333333 5.686666667 -0.252282755 Down 0.358964233 Cspg4 chondroitin sulfate proteoglycan 4 K08115|1|0.0|4433|mmu:121021|chondroitin sulfate proteoglycan 4 GO:0030027//lamellipodium;GO:0044431//Golgi apparatus part;GO:0005764//lysosome;GO:0016021//integral component of membrane;GO:0044459 GO:0060089;GO:0019900//kinase binding GO:0001934//positive regulation of protein phosphorylation;GO:0006027//glycosaminoglycan catabolic process;GO:0010975//regulation of neuron projection development;GO:0042551//neuron maturation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0006952//defense response;GO:0016477//cell migration gi|146231960|ref|NP_620570.2|/0/chondroitin sulfate proteoglycan 4 precursor [Mus musculus] 74665 1858 2.13 2.8 0.394573397 Up 0.358964233 Lrrc48 leucine rich repeat containing 48 K16770|1|7e-17|91.7|obi:106873246|centriolin;K17550|2|2e-14|83.6|hst:105189886|protein phosphatase 1 regulatory subunit 7 GO:0044424 - - gi|21312844|ref|NP_083320.1|/0/dynein regulatory complex subunit 3 [Mus musculus] 28036 2135 11.63 13.36 0.200068911 Up 0.358907819 Larp7 "La ribonucleoprotein domain family, member 7" K15191|1|0.0|938|mmu:28036|La-related protein 7 GO:0032991//macromolecular complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0036094//small molecule binding GO:0010467//gene expression gi|110665742|ref|NP_613059.2|/0/la-related protein 7 [Mus musculus] 213990 2376.95 42.22333333 47.22333333 0.161459403 Up 0.358860807 Agap3 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 3" "K12491|1|4e-166|587|mmu:213990|Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3" GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008047//enzyme activator activity;GO:0043130//ubiquitin binding;GO:0008289//lipid binding GO:0000302//response to reactive oxygen species;GO:0009411//response to UV;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0032012//regulation of ARF protein signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0030575//nuclear body organization;GO:0006606//protein import into nucleus "gi|966936461|ref|XP_014990784.1|/3.80591e-165/PREDICTED: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X3 [Macaca mulatta]" 54611 4205 3.05 2.353333333 -0.37410356 Down 0.358860807 Pde3a "phosphodiesterase 3A, cGMP inhibited" "K19021|1|0.0|1728|mmu:54611|cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17]" GO:0016020//membrane;GO:0044444//cytoplasmic part "GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0043167//ion binding;GO:0030551//cyclic nucleotide binding" GO:0071363//cellular response to growth factor stimulus;GO:0003006//developmental process involved in reproduction;GO:0010720//positive regulation of cell development;GO:0006915//apoptotic process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0046058//cAMP metabolic process;GO:0006721//terpenoid metabolic process;GO:0070305//response to cGMP;GO:0007126//meiotic nuclear division;GO:0043114//regulation of vascular permeability "gi|9055304|ref|NP_061249.1|/0/cGMP-inhibited 3',5'-cyclic phosphodiesterase A [Mus musculus]" 13138 5454.63 137.2 123.8233333 -0.147997279 Down 0.358851405 Dag1 dystroglycan 1 K06265|1|0.0|1451|mmu:13138|dystroglycan 1 - - - - 103466 5967 20.42333333 17.98666667 -0.183290503 Down 0.358842002 Nt5dc3 5'-nucleotidase domain containing 3 K01081|1|2e-48|197|phu:Phum_PHUM227090|5'-nucleotidase [EC:3.1.3.5] GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity;GO:0043169//cation binding - gi|111494223|ref|NP_780540.2|/0/5'-nucleotidase domain-containing protein 3 [Mus musculus] 70361 3576 21.16 18.72 -0.176759193 Down 0.358842002 Lman1 "lectin, mannose-binding, 1" "K10080|1|0.0|934|mmu:70361|lectin, mannose-binding 1" GO:0031224//intrinsic component of membrane;GO:0030016//myofibril;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0030016//myofibril;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0031090//organelle membrane GO:0048029//monosaccharide binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0048029//monosaccharide binding;GO:0046872//metal ion binding;GO:0005515//protein binding GO:0006996//organelle organization;GO:0016482//cytosolic transport;GO:0006886//intracellular protein transport;GO:0006996//organelle organization;GO:0016482//cytosolic transport;GO:0006886//intracellular protein transport gi|74152119|dbj|BAE32091.1|/0/unnamed protein product [Mus musculus] 54612 1900 0.233333333 0.58 1.313660479 Up 0.3588326 Sfrp5 secreted frizzled-related sequence protein 5 K02222|1|4e-167|590|mmu:54612|secreted frizzled-related protein 5 - - - gi|31560421|ref|NP_061250.2|/3.07393e-166/secreted frizzled-related protein 5 precursor [Mus musculus] 100038725 2691 0.693333333 0.32 -1.115477217 Down 0.35879499 Cep85l centrosomal protein 85-like K16766|1|0.0|1513|mmu:100038725|centrosomal protein CEP85 GO:0005815//microtubule organizing center - - gi|326368265|ref|NP_001191912.1|/0/centrosomal protein of 85 kDa-like [Mus musculus] 17134 1720 11.25666667 9.733333333 -0.20977381 Down 0.358663357 Mafg "v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)" K09037|1|4e-58|228|lve:103081071|transcription factor MAFF/G/K - - - gi|564375680|ref|XP_006247975.1|/1.29574e-59/PREDICTED: transcription factor MafG isoform X3 [Rattus norvegicus] 52609 2893 9.643333333 11.16666667 0.211594772 Up 0.358663357 Cbx7 chromobox 7 K11454|1|1e-69|267|mmu:52609|chromobox protein 7 GO:0031519//PcG protein complex;GO:0000785//chromatin GO:0003723//RNA binding;GO:0042393//histone binding GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter gi|21450179|ref|NP_659060.1|/9.91838e-69/chromobox protein homolog 7 [Mus musculus] 75223 1239 0.53 0.193333333 -1.45490196 Down 0.358644552 4930528D03Rik RIKEN cDNA 4930528D03 gene - - - - - 70351 3819.38 13.42 11.70333333 -0.197465176 Down 0.358550528 Ppp4r1 "protein phosphatase 4, regulatory subunit 1" K15424|1|0.0|768|mmu:70351|serine/threonine-protein phosphatase 4 regulatory subunit 1 GO:0008287//protein serine/threonine phosphatase complex;GO:0008287//protein serine/threonine phosphatase complex GO:0005488//binding;GO:0016791//phosphatase activity;GO:0019888//protein phosphatase regulator activity;GO:0005488//binding;GO:0016791//phosphatase activity GO:0006464//cellular protein modification process;GO:0007154//cell communication;GO:0006464//cellular protein modification process;GO:0007154//cell communication gi|44888281|sp|Q8K2V1.2|PP4R1_MOUSE/0/RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 15460 5501 9.64 8.283333333 -0.218821701 Down 0.358541126 Hr hairless K00478|1|0.0|2269|mmu:15460|lysine-specific demethylase hairless [EC:1.14.11.-] GO:0044451 GO:0043169//cation binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0019899//enzyme binding;GO:0008134//transcription factor binding "GO:0051259//protein oligomerization;GO:0044092//negative regulation of molecular function;GO:0006351//transcription, DNA-templated" gi|31544072|ref|NP_068677.2|/0/lysine-specific demethylase hairless [Mus musculus] 51792 2256 117.6866667 130.4 0.14799299 Up 0.358409493 Ppp2r1a "protein phosphatase 2, regulatory subunit A, alpha" K03456|1|0.0|1149|ecb:100062627|serine/threonine-protein phosphatase 2A regulatory subunit A GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0008287//protein serine/threonine phosphatase complex;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part GO:0004721//phosphoprotein phosphatase activity;GO:0046983//protein dimerization activity;GO:0019888//protein phosphatase regulator activity "GO:0006351//transcription, DNA-templated;GO:0042221//response to chemical;GO:0007155//cell adhesion;GO:0016055//Wnt signaling pathway;GO:0044772//mitotic cell cycle phase transition;GO:0006665//sphingolipid metabolic process;GO:0043407//negative regulation of MAP kinase activity;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006396//RNA processing;GO:0065003;GO:0012502//induction of programmed cell death;GO:0030154//cell differentiation;GO:0016049//cell growth;GO:0006470//protein dephosphorylation;GO:0006260//DNA replication" gi|958797809|ref|XP_014683432.1|/0/PREDICTED: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform [Equus asinus] 52898 622 117.44 129.95 0.146032761 Up 0.358315469 Rnasek "ribonuclease, RNase K" K19770|1|5e-49|196|pale:102897718|ribonuclease kappa [EC:3.1.-.-] GO:0031224//intrinsic component of membrane GO:0004519//endonuclease activity;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|33239393|ref|NP_776103.1|/3.35699e-48/ribonuclease kappa [Mus musculus] 118452 4177 0.153333333 0.473333333 1.626185163 Up 0.358221445 Baalc "brain and acute leukemia, cytoplasmic" - GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen - - gi|21687035|ref|NP_542371.1|/2.72234e-78/brain and acute leukemia cytoplasmic protein isoform 1-6-8 [Mus musculus] 30963 1003.87 41.84 46.67333333 0.157715654 Up 0.358118019 Hacd1 3-hydroxyacyl-CoA dehydratase 1 K10703|1|2e-139|497|mmu:30963|very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134] - - - - 67043 2316 9.71 8.363333333 -0.215393231 Down 0.358080409 Syap1 synapse associated protein 1 - GO:0043231//intracellular membrane-bounded organelle - - gi|270265917|ref|NP_080208.2|/2.32035e-150/synapse-associated protein 1 [Mus musculus] 69671 908 2.943333333 2.26 -0.381128165 Down 0.358071007 Tmem52 transmembrane protein 52 - GO:0031224//intrinsic component of membrane - - gi|359718962|ref|NP_001240787.1|/8.20706e-79/transmembrane protein 52 isoform 3 precursor [Mus musculus] 22276 1680.06 11.77333333 13.48333333 0.19565436 Up 0.358061604 Uros uroporphyrinogen III synthase K01719|1|1e-149|532|mmu:22276|uroporphyrinogen-III synthase [EC:4.2.1.75] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0016836//hydro-lyase activity;GO:0005488//binding;GO:0016836//hydro-lyase activity;GO:0005488//binding;GO:0016836//hydro-lyase activity;GO:0005488//binding;GO:0016836//hydro-lyase activity GO:0009636//response to toxic substance;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0046685//response to arsenic-containing substance;GO:0014075//response to amine;GO:0009636//response to toxic substance;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0046685//response to arsenic-containing substance;GO:0014075//response to amine;GO:0009636//response to toxic substance;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0046685//response to arsenic-containing substance;GO:0014075//response to amine;GO:0009636//response to toxic substance;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0046685//response to arsenic-containing substance;GO:0014075//response to amine "gi|148685827|gb|EDL17774.1|/1.02171e-161/uroporphyrinogen III synthase, isoform CRA_d, partial [Mus musculus]" 14976 728 40.75666667 45.57333333 0.161153833 Up 0.358061604 Pfdn6 prefoldin subunit 6 K04798|1|9e-56|218|pale:102887145|prefoldin beta subunit GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0005515//protein binding GO:0006458//'de novo' protein folding;GO:0043623//cellular protein complex assembly;GO:0006458//'de novo' protein folding;GO:0043623//cellular protein complex assembly gi|545838985|ref|XP_005665938.1|/2.26626e-55/PREDICTED: prefoldin subunit 6 isoform X1 [Sus scrofa] 269037 6192 5.596666667 4.626666667 -0.274594662 Down 0.358033397 Ctif CBP80/20-dependent translation initiation factor K14322|1|8e-13|80.1|xla:380223|polyadenylate-binding protein-interacting protein 1 - - - gi|145279233|ref|NP_958742.2|/0/CBP80/20-dependent translation initiation factor [Mus musculus] 71837 2050 0.316666667 0.683333333 1.109624491 Up 0.358033397 1700003E16Rik RIKEN cDNA 1700003E16 gene K09187|1|3e-06|56.6|nle:100586637|histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43] - - - gi|222831618|ref|NP_082224.1|/0/uncharacterized protein C2orf81 homolog [Mus musculus] 259277 919 4.943333333 4.056666667 -0.28518943 Down 0.358023995 Klk8 kallikrein related-peptidase 8 K08650|1|2e-157|557|mmu:259277|kallikrein 8 [EC:3.4.21.118] GO:0044424;GO:0044421;GO:0044424;GO:0044421 GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0050803//regulation of synapse structure or activity;GO:0007611//learning or memory;GO:0031641//regulation of myelination;GO:0008283//cell proliferation;GO:0031103//axon regeneration;GO:0019538//protein metabolic process;GO:0050803//regulation of synapse structure or activity;GO:0007611//learning or memory;GO:0031641//regulation of myelination;GO:0008283//cell proliferation;GO:0031103//axon regeneration;GO:0019538//protein metabolic process "gi|148690734|gb|EDL22681.1|/1.36025e-180/kallikrein 8, partial [Mus musculus]" 232944 2259 24.94333333 28.09333333 0.171573539 Up 0.358023995 Mark4 MAP/microtubule affinity regulating kinase 4 K08798|1|0.0|1355|mmu:232944|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] - - - - 20556 1684 7.16 8.403333333 0.231002125 Up 0.35800519 Slfn2 schlafen 2 - - - - gi|6755570|ref|NP_035538.1|/0/schlafen family member 12-like [Mus musculus] 74140 2516 14.03666667 16.01333333 0.190073276 Up 0.357986385 Tm9sf1 transmembrane 9 superfamily member 1 K17085|1|0.0|1118|mmu:74140|transmembrane 9 superfamily member 1 GO:0031982//vesicle;GO:0005764//lysosome;GO:0005774//vacuolar membrane;GO:0031224//intrinsic component of membrane - GO:0045184//establishment of protein localization;GO:0044248 gi|27229185|ref|NP_083056.2|/0/transmembrane 9 superfamily member 1 precursor [Mus musculus] 101314 1110 39.70333333 44.50333333 0.164653264 Up 0.357967581 Brk1 "BRICK1, SCAR/WAVE actin-nucleating complex subunit" K05752|1|2e-28|128|ssc:100522899|chromosome 3 open reading frame 10 GO:0043232 - GO:0043009//chordate embryonic development;GO:0006928//movement of cell or subcellular component;GO:0008283//cell proliferation;GO:0007010//cytoskeleton organization gi|6841250|gb|AAF28978.1|AF161418_1/3.71471e-29/HSPC300 [Homo sapiens] 665113 6994.6 3.58 2.826666667 -0.340857823 Down 0.357901764 Tnik TRAF2 and NCK interacting kinase K08840|1|0.0|1570|ngi:103731694|TRAF2 and NCK interacting kinase [EC:2.7.11.1] GO:0005768//endosome;GO:0043232;GO:0005768//endosome;GO:0043232;GO:0005768//endosome;GO:0043232;GO:0005768//endosome;GO:0043232 GO:0032550;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity;GO:0032550;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity;GO:0032550;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity;GO:0032550;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity GO:0048731//system development;GO:0007166//cell surface receptor signaling pathway;GO:0000186//activation of MAPKK activity;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0030036//actin cytoskeleton organization;GO:0048731//system development;GO:0007166//cell surface receptor signaling pathway;GO:0000186//activation of MAPKK activity;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0030036//actin cytoskeleton organization;GO:0048731//system development;GO:0007166//cell surface receptor signaling pathway;GO:0000186//activation of MAPKK activity;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0030036//actin cytoskeleton organization;GO:0048731//system development;GO:0007166//cell surface receptor signaling pathway;GO:0000186//activation of MAPKK activity;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0030036//actin cytoskeleton organization gi|244792600|ref|NP_001156479.1|/0/traf2 and NCK-interacting protein kinase isoform 2 [Mus musculus] 442820 1844 3.556666667 2.803333333 -0.343382471 Down 0.357901764 D830005E20Rik RIKEN cDNA D830005E20 gene - - - - - 56292 1018.21 41.52666667 46.3 0.156974122 Up 0.357835947 Naa10 "N(alpha)-acetyltransferase 10, NatA catalytic subunit" K00670|1|1e-126|454|mmu:56292|peptide alpha-N-acetyltransferase [EC:2.3.1.88] GO:0043231//intracellular membrane-bounded organelle GO:0034212//peptide N-acetyltransferase activity;GO:0043021//ribonucleoprotein complex binding GO:0006473//protein acetylation;GO:0016043//cellular component organization gi|817332518|ref|XP_012293331.1|/2.15821e-124/PREDICTED: N-alpha-acetyltransferase 10 isoform X1 [Aotus nancymaae] 69219 3747 2.5 3.21 0.360645202 Up 0.357817142 Ddah1 dimethylarginine dimethylaminohydrolase 1 K01482|1|1e-159|566|mmu:69219|dimethylargininase [EC:3.5.3.18] GO:0043231//intracellular membrane-bounded organelle "GO:0043169//cation binding;GO:0016813//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines;GO:0031406//carboxylic acid binding" GO:0006575//cellular modified amino acid metabolic process;GO:0001525//angiogenesis;GO:0019932//second-messenger-mediated signaling;GO:0008217//regulation of blood pressure;GO:0006525//arginine metabolic process;GO:0006809//nitric oxide biosynthetic process "gi|38371755|ref|NP_081269.1|/1.05975e-158/N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 [Mus musculus]" 20383 2901.32 19.96333333 17.57333333 -0.183964762 Down 0.357798338 Srsf3 serine/arginine-rich splicing factor 3 "K12892|1|3e-45|186|phd:102325457|splicing factor, arginine/serine-rich 3" GO:0016604//nuclear body;GO:0016604//nuclear body GO:0003676//nucleic acid binding;GO:0019899//enzyme binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0019899//enzyme binding;GO:0036094//small molecule binding GO:0000377;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006405//RNA export from nucleus;GO:0006397//mRNA processing;GO:0006366//transcription from RNA polymerase II promoter;GO:0000377;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006405//RNA export from nucleus;GO:0006397//mRNA processing;GO:0006366//transcription from RNA polymerase II promoter gi|940778081|ref|XP_014304389.1|/2.25519e-71/PREDICTED: serine/arginine-rich splicing factor 3 isoform X1 [Myotis lucifugus] 20430 6471 11.11666667 9.616666667 -0.209115443 Down 0.357713716 Cyfip1 cytoplasmic FMR1 interacting protein 1 K05749|1|0.0|2384|clv:102096482|cytoplasmic FMR1 interacting protein GO:0031252//cell leading edge;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0034518//RNA cap binding complex;GO:0031252//cell leading edge;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0034518//RNA cap binding complex;GO:0031252//cell leading edge;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0034518//RNA cap binding complex GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0022604//regulation of cell morphogenesis;GO:0007409//axonogenesis;GO:0030031//cell projection assembly;GO:0022604//regulation of cell morphogenesis;GO:0007409//axonogenesis;GO:0030031//cell projection assembly;GO:0022604//regulation of cell morphogenesis;GO:0007409//axonogenesis;GO:0030031//cell projection assembly gi|164698474|ref|NP_035500.2|/0/cytoplasmic FMR1-interacting protein 1 isoform a [Mus musculus] 668224 707 0.866666667 0.456666667 -0.92433573 Down 0.357469254 Gm9054 predicted gene 9054 - - - - - 228356 4231.17 14.08333333 16.04666667 0.1882848 Up 0.357356426 1110051M20Rik RIKEN cDNA 1110051M20 gene - GO:0031981//nuclear lumen - - gi|625185807|ref|XP_007608334.1|/0/PREDICTED: UPF0705 protein C11orf49 homolog isoform X2 [Cricetulus griseus] 29812 2650.05 9.523333333 11.01333333 0.20971265 Up 0.357187183 Ndrg3 N-myc downstream regulated gene 3 K18266|1|3e-122|442|cjo:107310564|protein NDRG1 GO:0044424;GO:0044424 - GO:0016049//cell growth;GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|7305307|ref|NP_038893.1|/0/protein NDRG3 isoform 2 [Mus musculus] 22269 890 0.34 0.063333333 -2.424497829 Down 0.35717778 Upk2 uroplakin 2 - GO:0044459;GO:0031227//intrinsic component of endoplasmic reticulum membrane - GO:0030154//cell differentiation gi|586160|sp|P38575.1|UPK2_MOUSE/6.93787e-67/RecName: Full=Uroplakin-2; Short=UP2; AltName: Full=Uroplakin II; Short=UPII; Flags: Precursor 70617 1603 1.443333333 2.01 0.477790977 Up 0.357158976 5730508B09Rik RIKEN cDNA 5730508B09 gene - GO:0031224//intrinsic component of membrane - - gi|28076961|ref|NP_081758.1|/2.63498e-51/uncharacterized protein C4orf32 homolog [Mus musculus] 218975 4493 7.556666667 6.413333333 -0.236675592 Down 0.357111964 Mapk1ip1l mitogen-activated protein kinase 1 interacting protein 1-like - - - - gi|344253328|gb|EGW09432.1|/3.99008e-67/Galectin-3 [Cricetulus griseus] 433931 4257 2.766666667 2.106666667 -0.393186778 Down 0.357055549 Pigg "phosphatidylinositol glycan anchor biosynthesis, class G" K05310|1|0.0|1758|mmu:433931|ethanolaminephosphotransferase [EC:2.7.-.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0051377//mannose-ethanolamine phosphotransferase activity;GO:0051377//mannose-ethanolamine phosphotransferase activity GO:0006497//protein lipidation;GO:0006497//protein lipidation gi|893570856|ref|NP_001297618.1|/0/GPI ethanolamine phosphate transferase 2 isoform 1 [Mus musculus] 105193 2308 2.316666667 3.003333333 0.374514128 Up 0.357027342 Nhlrc1 NHL repeat containing 1 K10602|1|0.0|710|mmu:105193|E3 ubiquitin-protein ligase NHLRC1 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination gi|30425030|ref|NP_780549.1|/0/E3 ubiquitin-protein ligase NHLRC1 [Mus musculus] 228980 4422 6.773333333 5.7 -0.248904077 Down 0.35698033 Taf4 TATA-box binding protein associated factor 4 K03129|1|0.0|1068|mmu:228980|transcription initiation factor TFIID subunit 4 GO:0044665//MLL1/2 complex;GO:0005667//transcription factor complex GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding GO:0006366//transcription from RNA polymerase II promoter;GO:0008585//female gonad development gi|124487354|ref|NP_001074561.1|/0/transcription initiation factor TFIID subunit 4 [Mus musculus] 50798 3648.93 8.04 9.373333333 0.221366687 Up 0.356876904 Gne glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase K12409|1|0.0|1374|hgl:101705910|bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:3.2.1.183 2.7.1.60] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part "GO:0043169//cation binding;GO:0032550;GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0043169//cation binding;GO:0032550;GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0016773//phosphotransferase activity, alcohol group as acceptor" GO:0022610;GO:0008610//lipid biosynthetic process;GO:0006054//N-acetylneuraminate metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0022610;GO:0008610//lipid biosynthetic process;GO:0006054//N-acetylneuraminate metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006044//N-acetylglucosamine metabolic process gi|568927006|ref|XP_006538136.1|/0/PREDICTED: bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1 [Mus musculus] 72401 2509.74 0.986666667 1.486666667 0.591446534 Up 0.356858099 Slc43a1 "solute carrier family 43, member 1" "K08228|1|0.0|1077|mmu:72401|MFS transporter, LAT3 family, solute carrier family 43, member 1" GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0015171//amino acid transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity GO:0044763;GO:0006865//amino acid transport;GO:0044763;GO:0006865//amino acid transport;GO:0044763;GO:0006865//amino acid transport gi|139949132|ref|NP_001074818.2|/0/large neutral amino acids transporter small subunit 3 isoform 1 [Mus musculus] 232853 2042 2.466666667 1.85 -0.415037499 Down 0.356858099 Zfp954 zinc finger protein 954 K09228|1|0.0|880|mmu:232853|KRAB domain-containing zinc finger protein - - - - 12914 7507 4.843333333 3.96 -0.290499867 Down 0.356858099 Crebbp CREB binding protein K04498|1|0.0|3832|mmu:12914|E1A/CREB-binding protein [EC:2.3.1.48] GO:0000785//chromatin;GO:0000777//condensed chromosome kinetochore;GO:0016604//nuclear body "GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0003712//transcription cofactor activity;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0008080//N-acetyltransferase activity;GO:0043425//bHLH transcription factor binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0016570//histone modification;GO:0006474//N-terminal protein amino acid acetylation;GO:0010564//regulation of cell cycle process;GO:0019827//stem cell population maintenance;GO:0044093 gi|70995311|ref|NP_001020603.1|/0/CREB-binding protein [Mus musculus] 66568 1698 0.17 0.503333333 1.565979397 Up 0.356839294 Rwdd3 RWD domain containing 3 - - - - - 70101 2192 1.923333333 2.56 0.412534992 Up 0.356839294 Cyp4f16 "cytochrome P450, family 4, subfamily f, polypeptide 16" "K00490|1|0.0|1004|mmu:70101|cytochrome P450, family 4, subfamily F [EC:1.14.14.1];K17726|3|0.0|883|cge:100773326|leukotriene-B4 20-monooxygenase / phylloquinone omega-hydroxylase [EC:1.14.13.30 1.14.13.194]" GO:0031090//organelle membrane "GO:0046906//tetrapyrrole binding;GO:0043169//cation binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0006952//defense response;GO:0006690//icosanoid metabolic process "gi|148708358|gb|EDL40305.1|/0/mCG14244, isoform CRA_b, partial [Mus musculus]" 21808 5116 1.7 2.303333333 0.438188464 Up 0.356651247 Tgfb2 "transforming growth factor, beta 2" K13376|1|0.0|745|mmu:21808|transforming growth factor beta-2 - - - - 71733 3255 2.29 1.693333333 -0.435481602 Down 0.356651247 Susd2 sushi domain containing 2 K17613|1|2e-91|340|myb:102248525|calcineurin-binding protein cabin-1;K13912|2|2e-37|160|aqu:105312476|deleted in malignant brain tumors 1 protein;K17307|3|1e-34|151|tad:TRIADDRAFT_53733|fibulin 1/2;K06825|4|2e-33|147|bfo:BRAFLDRAFT_129967|fibrillin 1 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0001871;GO:0038024//cargo receptor activity;GO:0001871;GO:0038024//cargo receptor activity GO:0002376//immune system process;GO:0002376//immune system process gi|251823824|ref|NP_082166.3|/0/sushi domain-containing protein 2 isoform 1 precursor [Mus musculus] 15502 3418 11.16333333 9.683333333 -0.205192212 Down 0.356651247 Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 K09502|1|0.0|724|rno:65028|DnaJ homolog subfamily A member 1 - - - - 76816 2771 1.666666667 2.266666667 0.443606651 Up 0.356651247 Sdccag8 serologically defined colon cancer antigen 8 K16488|1|0.0|1155|mmu:76816|serologically defined colon cancer antigen 8 GO:0030054//cell junction;GO:0005813//centrosome - GO:0048646//anatomical structure formation involved in morphogenesis;GO:0007163//establishment or maintenance of cell polarity gi|29789245|ref|NP_084032.1|/0/serologically defined colon cancer antigen 8 homolog [Mus musculus] 73327 1027.85 6.096666667 5.093333333 -0.259410532 Down 0.356632442 Pradc1 protease-associated domain containing 1 "K10086|1|4e-11|71.6|spu:579538|ER degradation enhancer, mannosidase alpha-like 3" - - - gi|625212555|ref|XP_007646984.1|/3.30391e-94/PREDICTED: protease-associated domain-containing protein 1 isoform X1 [Cricetulus griseus] 223646 1890 7.906666667 9.23 0.223261044 Up 0.356444394 Naprt nicotinate phosphoribosyltransferase K00763|1|0.0|986|mmu:223646|nicotinate phosphoribosyltransferase [EC:6.3.4.21] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0016763//transferase activity, transferring pentosyl groups" GO:0019357//nicotinate nucleotide biosynthetic process;GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0006950//response to stress "gi|148697546|gb|EDL29493.1|/0/nicotinate phosphoribosyltransferase domain containing 1, isoform CRA_a, partial [Mus musculus]" 13135 714.34 91.7 102.0066667 0.153669804 Up 0.356434992 Dad1 defender against cell death 1 K12668|1|5e-48|196|ocu:100355816|oligosaccharyltransferase complex subunit epsilon GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane GO:0004576//oligosaccharyl transferase activity;GO:0004576//oligosaccharyl transferase activity GO:0006915//apoptotic process;GO:0031667//response to nutrient levels;GO:0042221//response to chemical;GO:0001701//in utero embryonic development;GO:0006487//protein N-linked glycosylation;GO:0006915//apoptotic process;GO:0031667//response to nutrient levels;GO:0042221//response to chemical;GO:0001701//in utero embryonic development;GO:0006487//protein N-linked glycosylation gi|655863889|ref|XP_002718104.2|/4.70328e-48/PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 [Oryctolagus cuniculus] 434218 1535 0.6 0.253333333 -1.243925583 Down 0.35642559 Trim34b tripartite motif-containing 34B K11999|1|0.0|975|mmu:434218|tripartite motif-containing protein 6/22/34 - - - gi|345199315|ref|NP_001230845.1|/0/tripartite motif-containing 34B [Mus musculus] 68137 1525 94.46666667 104.7566667 0.149164802 Up 0.356406785 Kdelr1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 K10949|1|1e-110|402|chx:102183096|ER lumen protein retaining receptor GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046923//ER retention sequence binding GO:0035437//maintenance of protein localization in endoplasmic reticulum;GO:0015031//protein transport gi|926714898|ref|XP_005692735.2|/8.90341e-110/PREDICTED: ER lumen protein-retaining receptor 1 [Capra hircus] 252972 4666 23.78333333 26.8 0.172282072 Up 0.356397382 Tpcn1 two pore channel 1 K16896|1|0.0|1456|mmu:252972|two pore calcium channel protein 1 - - - - 68118 1230 14.10333333 16.03333333 0.185038208 Up 0.356397382 Atg101 autophagy related 101 K19730|1|3e-121|437|mmu:68118|autophagy-related protein 101 GO:0044444//cytoplasmic part GO:0005515//protein binding GO:0044248;GO:0007033//vacuole organization gi|402794103|ref|NP_001007660.2|/6.8867e-124/autophagy-related protein 101 isoform 1 [Rattus norvegicus] 19122 3579.4 91.76 102.0266667 0.153008982 Up 0.356378578 Prnp prion protein K05634|1|1e-86|323|mmu:19122|prion protein GO:0043231//intracellular membrane-bounded organelle;GO:0044425;GO:0043231//intracellular membrane-bounded organelle;GO:0044425 GO:0046914//transition metal ion binding;GO:0015631//tubulin binding;GO:0046914//transition metal ion binding;GO:0015631//tubulin binding GO:0033173//calcineurin-NFAT signaling cascade;GO:0030003//cellular cation homeostasis;GO:0001818//negative regulation of cytokine production;GO:0042130//negative regulation of T cell proliferation;GO:0006915//apoptotic process;GO:0044092//negative regulation of molecular function;GO:0050852//T cell receptor signaling pathway;GO:0010038//response to metal ion;GO:0006725//cellular aromatic compound metabolic process;GO:0006950//response to stress;GO:0033173//calcineurin-NFAT signaling cascade;GO:0030003//cellular cation homeostasis;GO:0001818//negative regulation of cytokine production;GO:0042130//negative regulation of T cell proliferation;GO:0006915//apoptotic process;GO:0044092//negative regulation of molecular function;GO:0050852//T cell receptor signaling pathway;GO:0010038//response to metal ion;GO:0006725//cellular aromatic compound metabolic process;GO:0006950//response to stress gi|74186102|dbj|BAE34221.1|/1.55684e-85/unnamed protein product [Mus musculus] 15161 8138 12.65 10.99 -0.202945999 Down 0.356256347 Hcfc1 host cell factor C1 K14966|1|0.0|2933|mmu:15161|host cell factor GO:0044665//MLL1/2 complex;GO:0000123//histone acetyltransferase complex;GO:0044297//cell body GO:0005515//protein binding;GO:0010485//H4 histone acetyltransferase activity;GO:0003712//transcription cofactor activity GO:0000278//mitotic cell cycle;GO:0043967//histone H4 acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0006461//protein complex assembly;GO:0019042 gi|34328130|ref|NP_032250.2|/0/host cell factor 1 precursor [Mus musculus] 56017 2083 11.47333333 13.13666667 0.195314652 Up 0.356256347 Slc2a8 "solute carrier family 2, (facilitated glucose transporter), member 8" "K08145|1|0.0|885|mmu:56017|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8" GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle;GO:0012506//vesicle membrane GO:0048029//monosaccharide binding;GO:0005353//fructose transmembrane transporter activity GO:0019318//hexose metabolic process;GO:0008645//hexose transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007127//meiosis I;GO:0006950//response to stress "gi|9506735|ref|NP_062361.1|/0/solute carrier family 2, facilitated glucose transporter member 8 [Mus musculus]" 78977 1851 17.86 20.18 0.176194094 Up 0.356246944 Popdc3 popeye domain containing 3 - GO:0031224//intrinsic component of membrane - - "gi|148673090|gb|EDL05037.1|/6.63972e-166/popeye domain containing 3, isoform CRA_a, partial [Mus musculus]" 19108 3217 7.436666667 6.31 -0.237016103 Down 0.356209335 Prkx "protein kinase, X-linked" K19584|1|0.0|703|mmu:19108|protein kinase X [EC:2.7.11.11] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0005515//protein binding;GO:0004690//cyclic nucleotide-dependent protein kinase activity GO:0016477//cell migration;GO:0006468//protein phosphorylation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030097//hemopoiesis;GO:0007155//cell adhesion;GO:0030856//regulation of epithelial cell differentiation;GO:0001822//kidney development;GO:0002009//morphogenesis of an epithelium;GO:0050673//epithelial cell proliferation gi|23956080|ref|NP_058675.1|/0/cAMP-dependent protein kinase catalytic subunit PRKX [Mus musculus] 211914 5588.91 6.566666667 5.506666667 -0.253981943 Down 0.356162323 Asap2 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 2" "K12488|1|0.0|1721|mmu:211914|Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein" GO:0000139//Golgi membrane;GO:0000139//Golgi membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0046914//transition metal ion binding;GO:0008289//lipid binding;GO:0046914//transition metal ion binding;GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0008047//enzyme activator activity;GO:0046914//transition metal ion binding;GO:0008289//lipid binding GO:0032012//regulation of ARF protein signal transduction;GO:0044093;GO:0032012//regulation of ARF protein signal transduction;GO:0044093;GO:0032012//regulation of ARF protein signal transduction "gi|206597526|ref|NP_001128664.1|/0/arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 isoform c [Mus musculus]" 63828 1011.38 26.24666667 23.25666667 -0.174489879 Down 0.356077701 Fn3k fructosamine 3 kinase K15522|1|0.0|637|mmu:63828|protein-fructosamine 3-kinase [EC:2.7.1.171] - GO:0016301//kinase activity;GO:0016301//kinase activity GO:0006040//amino sugar metabolic process;GO:0006520//cellular amino acid metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006040//amino sugar metabolic process;GO:0006520//cellular amino acid metabolic process;GO:0006796//phosphate-containing compound metabolic process gi|11528496|ref|NP_071297.1|/0/fructosamine-3-kinase isoform a [Mus musculus] 11350 6255.19 15.41666667 13.49333333 -0.192244076 Down 0.356077701 Abl1 "c-abl oncogene 1, non-receptor tyrosine kinase" K06619|1|0.0|1999|mmu:11350|abelson tyrosine-protein kinase 1 [EC:2.7.10.2] GO:0031981//nuclear lumen;GO:0031252//cell leading edge;GO:0043232;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0031252//cell leading edge;GO:0043232;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0031252//cell leading edge;GO:0043232;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0031252//cell leading edge;GO:0043232;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0031252//cell leading edge;GO:0043232;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0032550;GO:0019901//protein kinase binding;GO:0004713//protein tyrosine kinase activity;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0046914//transition metal ion binding;GO:0032550;GO:0019901//protein kinase binding;GO:0004713//protein tyrosine kinase activity;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0046914//transition metal ion binding;GO:0032550;GO:0019901//protein kinase binding;GO:0004713//protein tyrosine kinase activity;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0046914//transition metal ion binding;GO:0032550;GO:0019901//protein kinase binding;GO:0004713//protein tyrosine kinase activity;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0046914//transition metal ion binding;GO:0032550;GO:0019901//protein kinase binding;GO:0004713//protein tyrosine kinase activity;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding GO:0001934//positive regulation of protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0043085//positive regulation of catalytic activity;GO:0006974//cellular response to DNA damage stimulus;GO:0006469//negative regulation of protein kinase activity;GO:0006915//apoptotic process;GO:0006259//DNA metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0022610;GO:0016192//vesicle-mediated transport;GO:0044248;GO:0007049//cell cycle;GO:0035556//intracellular signal transduction;GO:0001934//positive regulation of protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0043085//positive regulation of catalytic activity;GO:0006974//cellular response to DNA damage stimulus;GO:0006469//negative regulation of protein kinase activity;GO:0006915//apoptotic process;GO:0006259//DNA metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0022610;GO:0016192//vesicle-mediated transport;GO:0044248;GO:0007049//cell cycle;GO:0035556//intracellular signal transduction;GO:0001934//positive regulation of protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0043085//positive regulation of catalytic activity;GO:0006974//cellular response to DNA damage stimulus;GO:0006469//negative regulation of protein kinase activity;GO:0006915//apoptotic process;GO:0006259//DNA metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0022610;GO:0016192//vesicle-mediated transport;GO:0044248;GO:0007049//cell cycle;GO:0035556//intracellular signal transduction;GO:0001934//positive regulation of protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0043085//positive regulation of catalytic activity;GO:0006974//cellular response to DNA damage stimulus;GO:0006469//negative regulation of protein kinase activity;GO:0006915//apoptotic process;GO:0006259//DNA metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0022610;GO:0016192//vesicle-mediated transport;GO:0044248;GO:0007049//cell cycle;GO:0035556//intracellular signal transduction;GO:0001934//positive regulation of protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0043085//positive regulation of catalytic activity;GO:0006974//cellular response to DNA damage stimulus;GO:0006469//negative regulation of protein kinase activity;GO:0006915//apoptotic process;GO:0006259//DNA metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0022610;GO:0016192//vesicle-mediated transport;GO:0044248;GO:0007049//cell cycle;GO:0035556//intracellular signal transduction gi|162951870|ref|NP_001106174.1|/0/tyrosine-protein kinase ABL1 isoform a [Mus musculus] 230579 1966 5.59 4.636666667 -0.269760269 Down 0.356021287 Fam151a "family with sequence simliarity 151, member A" "K04679|1|2e-16|90.5|aam:106496341|MAD, mothers against decapentaplegic interacting protein" GO:0031224//intrinsic component of membrane - - gi|22165388|ref|NP_666261.1|/0/protein FAM151A [Mus musculus] 216543 4810 12.84333333 11.19 -0.198809649 Down 0.355823837 Cep68 centrosomal protein 68 K16764|1|0.0|1424|mmu:216543|centrosomal protein CEP68 GO:0005815//microtubule organizing center - GO:0031023//microtubule organizing center organization "gi|148675886|gb|EDL07833.1|/0/centrosomal protein 68, isoform CRA_b, partial [Mus musculus]" 105980075 5324 15.29333333 13.38666667 -0.192106122 Down 0.35579563 Dpm1-adnp Dpm1-adnp readthrough K00721|1|7e-138|495|mmu:13480|dolichol-phosphate mannosyltransferase [EC:2.4.1.83] GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044421 GO:0001071//nucleic acid binding transcription factor activity;GO:0033218//amide binding;GO:0003677//DNA binding;GO:0015631//tubulin binding;GO:0046914//transition metal ion binding "GO:0033483;GO:0006471//protein ADP-ribosylation;GO:0007416//synapse assembly;GO:0007268//chemical synaptic transmission;GO:0007613//memory;GO:0006351//transcription, DNA-templated;GO:0010033//response to organic substance;GO:0010975//regulation of neuron projection development;GO:0030307//positive regulation of cell growth;GO:0043393//regulation of protein binding;GO:0006182//cGMP biosynthetic process;GO:0022602//ovulation cycle process;GO:0043066//negative regulation of apoptotic process;GO:0045860//positive regulation of protein kinase activity" gi|90093349|ref|NP_033758.2|/0/activity-dependent neuroprotector homeobox protein isoform 1 [Mus musculus] 23863 1225 13.65666667 15.56666667 0.188854657 Up 0.35579563 Dand5 "DAN domain family member 5, BMP antagonist" K01645|1|7e-08|60.8|cge:100764648|cerberus 1;K19558|2|4e-07|58.5|spu:105437446|neuroblastoma suppressor of tumorigenicity 1 - GO:0005488//binding;GO:0005488//binding GO:0032926//negative regulation of activin receptor signaling pathway;GO:0035581//sequestering of extracellular ligand from receptor;GO:0003140//determination of left/right asymmetry in lateral mesoderm;GO:0030509//BMP signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0003231//cardiac ventricle development;GO:0003230//cardiac atrium development;GO:0032926//negative regulation of activin receptor signaling pathway;GO:0035581//sequestering of extracellular ligand from receptor;GO:0003140//determination of left/right asymmetry in lateral mesoderm;GO:0030509//BMP signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0003231//cardiac ventricle development;GO:0003230//cardiac atrium development gi|41054862|ref|NP_957679.1|/1.31384e-95/DAN domain family member 5 precursor [Mus musculus] 20318 2400.11 41.02666667 36.63333333 -0.163404962 Down 0.355786227 Sdf4 stromal cell derived factor 4 K19934|1|0.0|716|mmu:20318|calcium-binding protein GO:0005768//endosome;GO:0044431//Golgi apparatus part;GO:0016020//membrane;GO:0005768//endosome;GO:0044431//Golgi apparatus part;GO:0016020//membrane;GO:0005768//endosome;GO:0044431//Golgi apparatus part;GO:0016020//membrane;GO:0005768//endosome;GO:0044431//Golgi apparatus part;GO:0016020//membrane GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding GO:0009411//response to UV;GO:0022037//metencephalon development;GO:0097305//response to alcohol;GO:0017156//calcium ion regulated exocytosis;GO:0030154//cell differentiation;GO:0009411//response to UV;GO:0022037//metencephalon development;GO:0097305//response to alcohol;GO:0017156//calcium ion regulated exocytosis;GO:0030154//cell differentiation;GO:0009411//response to UV;GO:0022037//metencephalon development;GO:0097305//response to alcohol;GO:0017156//calcium ion regulated exocytosis;GO:0030154//cell differentiation;GO:0009411//response to UV;GO:0022037//metencephalon development;GO:0097305//response to alcohol;GO:0017156//calcium ion regulated exocytosis;GO:0030154//cell differentiation "gi|148683118|gb|EDL15065.1|/0/stromal cell derived factor 4, isoform CRA_b, partial [Mus musculus]" 319622 6891 5.93 4.943333333 -0.262547913 Down 0.355776825 Itpripl2 "inositol 1,4,5-triphosphate receptor interacting protein-like 2" - GO:0031224//intrinsic component of membrane - - "gi|83921560|ref|NP_001028552.1|/0/inositol 1,4,5-trisphosphate receptor-interacting protein-like 2 precursor [Mus musculus]" 215814 1166 7.076666667 8.29 0.228302136 Up 0.355739215 Ccdc28a coiled-coil domain containing 28A - - - - gi|947239697|ref|XP_014444317.1|/7.7282e-81/PREDICTED: coiled-coil domain-containing protein 28A [Tupaia chinensis] 13032 6387.46 7.036666667 8.243333333 0.228335661 Up 0.355739215 Ctsc cathepsin C K01275|1|0.0|964|mmu:13032|cathepsin C [EC:3.4.14.1] - - - - 210009 3782.12 4.77 3.9 -0.290515142 Down 0.355692204 Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase K00597|1|0.0|822|mmu:210009|methionine synthase reductase [EC:1.16.1.8] - - - - 66648 3914.16 3.84 4.706666667 0.293599372 Up 0.355692204 Tpgs2 tubulin polyglutamylase complex subunit 2 K16605|1|6e-127|458|mmu:66648|tubulin polyglutamylase complex subunit 2 GO:0015630//microtubule cytoskeleton - - gi|218156330|ref|NP_001004361.2|/1.0116e-132/tubulin polyglutamylase complex subunit 2 isoform a [Mus musculus] 100740 1173 1.07 0.63 -0.764187063 Down 0.355682801 AI839979 expressed sequence AI839979 - - - - "gi|148705430|gb|EDL37377.1|/2.44465e-50/mCG1046215, partial [Mus musculus]" 12986 3583 1.473333333 2.046666667 0.474192286 Up 0.355588777 Csf3r colony stimulating factor 3 receptor (granulocyte) K05061|1|0.0|910|mmu:12986|granulocyte colony-stimulating factor receptor GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0022610;GO:0030595//leukocyte chemotaxis;GO:0022610;GO:0030595//leukocyte chemotaxis;GO:0022610;GO:0030595//leukocyte chemotaxis gi|165905615|ref|NP_031808.2|/0/granulocyte colony-stimulating factor receptor isoform 1 precursor [Mus musculus] 22755 3510 1.506666667 2.08 0.465223256 Up 0.355588777 Zfp93 zinc finger protein 93 K09228|1|0.0|1398|mmu:22755|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|6677629|ref|NP_033593.1|/0/zinc finger protein 235 [Mus musculus] 67695 552.32 85.42 94.86666667 0.151327358 Up 0.35556057 Ost4 oligosaccharyltransferase complex subunit 4 (non-catalytic) "K05128|1|2e-15|84.0|bom:102281106|RYK receptor-like tyrosine kinase [EC:2.7.10.1];K13355|2|2e-07|57.0|phu:Phum_PHUM379780|nucleoside diphosphate-linked moiety X motif 19, mitochondrial [EC:3.6.1.-]" - - - gi|671015515|ref|XP_008698559.1|/5.59674e-39/PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 [Ursus maritimus] 100042889 1726 1.146666667 0.693333333 -0.725825037 Down 0.355513558 C920021L13Rik RIKEN cDNA C920021L13 gene - - - - gi|755503748|ref|XP_011238398.1|/1.31699e-11/PREDICTED: uncharacterized protein C1orf54 homolog isoform X3 [Mus musculus] 103406 3358 1.206666667 0.746666667 -0.692490965 Down 0.355504156 Zfr2 zinc finger RNA binding protein 2 K13203|1|0.0|706|cmy:102938687|zinc finger RNA-binding protein - - - gi|163954931|ref|NP_001030067.2|/0/zinc finger RNA-binding protein 2 [Mus musculus] 17120 2640 7.413333333 6.293333333 -0.236298023 Down 0.355325511 Mad1l1 MAD1 mitotic arrest deficient 1-like 1 K06638|1|0.0|1258|mmu:17120|mitotic spindle assembly checkpoint protein MAD1 GO:0000776//kinetochore;GO:0005819//spindle;GO:0005635//nuclear envelope - GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0051983//regulation of chromosome segregation gi|88014564|ref|NP_034882.2|/0/mitotic spindle assembly checkpoint protein MAD1 [Mus musculus] 75476 436 6.73 5.676666667 -0.245562476 Down 0.355297303 1700010I02Rik RIKEN cDNA 1700010I02 gene - - - - - 65106 1339 81.88666667 91.16333333 0.154825115 Up 0.355297303 Arl6ip5 ADP-ribosylation factor-like 6 interacting protein 5 K20393|1|8e-96|353|mmu:65106|PRA1 family protein 3 GO:0043232;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0005515//protein binding GO:0006835//dicarboxylic acid transport "gi|149036808|gb|EDL91426.1|/2.02588e-107/ADP-ribosylation factor-like 6 interacting protein 5, isoform CRA_b [Rattus norvegicus]" 214345 2831.84 5.483333333 6.53 0.252029814 Up 0.355297303 Lrrc1 leucine rich repeat containing 1 K16175|1|7e-160|567|fch:102045760|protein scribble GO:0044424;GO:0044424 - - "gi|28302239|gb|AAH46591.1|/0/Lrrc1 protein, partial [Mus musculus]" 103140 1873 2.633333333 1.993333333 -0.401707169 Down 0.355287901 Gstt3 "glutathione S-transferase, theta 3" K00799|1|3e-136|488|mmu:103140|glutathione S-transferase [EC:2.5.1.18] - GO:0003824//catalytic activity GO:0006790//sulfur compound metabolic process "gi|21536248|ref|NP_598755.1|/2.76733e-135/glutathione S-transferase, theta 3 [Mus musculus]" 381410 3740 2.706666667 2.06 -0.393872889 Down 0.355259694 Zfp408 zinc finger protein 408 K09228|1|7e-73|278|cfr:102518130|KRAB domain-containing zinc finger protein - - - gi|568917670|ref|XP_006499894.1|/0/PREDICTED: zinc finger protein 408 isoform X1 [Mus musculus] 56047 2135 0.03 0.273333333 3.187627003 Up 0.355240889 Msln mesothelin K01069|1|2e-49|199|mgp:100548105|hydroxyacylglutathione hydrolase [EC:3.1.2.6] GO:0044421;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0022610;GO:0044767//single-organism developmental process gi|9256568|ref|NP_061345.1|/0/mesothelin precursor [Mus musculus] 27993 2249 6.9 8.1 0.231325546 Up 0.355034037 Imp4 "IMP4, U3 small nucleolar ribonucleoprotein" K14561|1|9e-155|550|rno:316317|U3 small nucleolar ribonucleoprotein protein IMP4 - - - - 75394 1629.76 0.943333333 1.433333333 0.603534607 Up 0.354996427 0610040F04Rik RIKEN cDNA 0610040F04 gene - - - - - 13616 3117 1.08 0.643333333 -0.747392966 Down 0.354949415 Edn3 endothelin 3 K05227|1|2e-117|426|mmu:13616|endothelin-3 GO:0044421 GO:0005102//receptor binding GO:0002027//regulation of heart rate;GO:0001990//regulation of systemic arterial blood pressure by hormone;GO:0046879//hormone secretion;GO:0007269//neurotransmitter secretion;GO:0008283//cell proliferation;GO:0002687//positive regulation of leukocyte migration;GO:0042310//vasoconstriction;GO:0007067//mitotic nuclear division;GO:0002790//peptide secretion;GO:0050931//pigment cell differentiation;GO:0043405//regulation of MAP kinase activity;GO:0014821;GO:0019932//second-messenger-mediated signaling;GO:0030595//leukocyte chemotaxis gi|6681267|ref|NP_031929.1|/1.81548e-116/endothelin-3 preproprotein [Mus musculus] 67917 3089 5.506666667 4.566666667 -0.270037794 Down 0.354921208 Zcchc3 "zinc finger, CCHC domain containing 3" "K05189|1|1e-44|184|lcm:102350988|gamma-aminobutyric acid receptor subunit pi;K14388|2|1e-43|181|lcm:102363950|solute carrier family 5 (sodium-coupled monocarboxylate transporter), member 8/12;K09250|3|2e-08|64.3|oas:101112704|cellular nucleic acid-binding protein" - GO:0046914//transition metal ion binding - "gi|148674019|gb|EDL05966.1|/0/zinc finger, CCHC domain containing 3, partial [Mus musculus]" 214424 2483 2.406666667 1.793333333 -0.424392664 Down 0.354751965 Parp16 "poly (ADP-ribose) polymerase family, member 16" K00774|1|1e-172|609|mmu:214424|poly [ADP-ribose] polymerase 16 [EC:2.4.2.30] GO:0005635//nuclear envelope;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane "GO:0016763//transferase activity, transferring pentosyl groups" GO:0035966//response to topologically incorrect protein "gi|15928508|gb|AAH14731.1|/0/Parp16 protein, partial [Mus musculus]" 100169864 1151 1.07 1.576666667 0.559266886 Up 0.354751965 Gm44504 "predicted readthrough transcript (NMD candidate), 44504" K00036|1|1e-10|69.7|bacu:103016715|glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] - - - - 73724 714 78.52333333 87.35666667 0.15379639 Up 0.35473316 Mcee methylmalonyl CoA epimerase K05606|1|1e-88|328|mmu:73724|methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity GO:0015936//coenzyme A metabolic process "gi|58037329|ref|NP_082902.1|/7.90911e-88/methylmalonyl-CoA epimerase, mitochondrial precursor [Mus musculus]" 67672 443 4.716666667 3.856666667 -0.290413189 Down 0.354667344 0610040B10Rik RIKEN cDNA 0610040B10 gene - - - - - 57741 2785 16.94666667 19.19666667 0.179854292 Up 0.354657941 Noc2l NOC2 like nucleolar associated transcriptional repressor K14833|1|0.0|1165|mmu:57741|nucleolar complex protein 2 GO:0031981//nuclear lumen GO:0003712//transcription cofactor activity;GO:0003682//chromatin binding;GO:0008134//transcription factor binding GO:0006366//transcription from RNA polymerase II promoter;GO:0009411//response to UV;GO:0001783//B cell apoptotic process;GO:0044765//single-organism transport;GO:0016573//histone acetylation gi|124301227|ref|NP_067278.2|/0/nucleolar complex protein 2 homolog [Mus musculus] 243372 4083 4.25 5.15 0.277109591 Up 0.354639136 Zfp775 zinc finger protein 775 K09228|1|9e-119|431|gja:107111912|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|27734126|ref|NP_775605.1|/0/zinc finger protein 775 [Mus musculus] 66109 1923 25.46666667 22.61 -0.171649145 Down 0.354639136 Tspan13 tetraspanin 13 K17356|1|6e-107|390|mmu:66109|tetraspanin-13/31 GO:0016021//integral component of membrane - - "gi|148704909|gb|EDL36856.1|/9.19765e-126/tetraspanin 13, isoform CRA_b, partial [Mus musculus]" 18791 2570 9.15 10.58666667 0.210404763 Up 0.354620332 Plat "plasminogen activator, tissue" K01343|1|0.0|1185|mmu:18791|tissue plasminogen activator [EC:3.4.21.68] "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0044421" GO:0004175//endopeptidase activity GO:0007270//neuron-neuron synaptic transmission;GO:0009611//response to wounding;GO:0031638//zymogen activation;GO:0046683//response to organophosphorus;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0050804//modulation of synaptic transmission;GO:0031960//response to corticosteroid;GO:0006508//proteolysis;GO:0030728//ovulation;GO:0014812//muscle cell migration gi|170763477|ref|NP_032898.2|/0/tissue-type plasminogen activator preproprotein [Mus musculus] 66366 1297 36.65 40.86666667 0.157111375 Up 0.354592125 Ergic3 ERGIC and golgi 3 K20367|1|0.0|751|mmu:66366|endoplasmic reticulum-Golgi intermediate compartment protein 3 GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane - GO:0006810//transport gi|564343767|ref|XP_006235376.1|/0/PREDICTED: endoplasmic reticulum-Golgi intermediate compartment protein 3 isoform X1 [Rattus norvegicus] 72297 2103 5.453333333 6.493333333 0.251820929 Up 0.354432284 B3gnt3 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3" "K07970|1|0.0|724|mmu:72297|beta-1,3-N-acetylglucosaminyltransferase 3 [EC:2.4.1.-]" GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0012505//endomembrane system "GO:0016758//transferase activity, transferring hexosyl groups" GO:0006024//glycosaminoglycan biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0006493//protein O-linked glycosylation "gi|170784852|ref|NP_082465.3|/0/N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 precursor [Mus musculus]" 16971 14907 19 16.76666667 -0.180403519 Down 0.354206627 Lrp1 low density lipoprotein receptor-related protein 1 K04550|1|0.0|9441|mmu:16971|low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor) GO:0043005//neuron projection;GO:0030135//coated vesicle;GO:0044297//cell body;GO:0016021//integral component of membrane;GO:0012505//endomembrane system GO:0005515//protein binding;GO:0046872//metal ion binding GO:0006909//phagocytosis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0016125//sterol metabolic process;GO:0014909//smooth muscle cell migration;GO:0043066//negative regulation of apoptotic process;GO:0016055//Wnt signaling pathway;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0015031//protein transport;GO:0035904//aorta development;GO:0030036//actin cytoskeleton organization;GO:0010874//regulation of cholesterol efflux;GO:0010517//regulation of phospholipase activity;GO:0019538//protein metabolic process gi|124494256|ref|NP_032538.2|/0/prolow-density lipoprotein receptor-related protein 1 precursor [Mus musculus] 67899 1188 10.68333333 9.256666667 -0.20679718 Down 0.354187822 Cmc1 COX assembly mitochondrial protein 1 K18171|1|3e-56|221|mmu:67899|COX assembly mitochondrial protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding - "gi|29145107|gb|AAH48547.1|/3.35559e-63/Cmc1 protein, partial [Mus musculus]" 22428 1181.19 34.15 38.28666667 0.164956482 Up 0.35414081 Dctn6 dynactin 6 K10428|1|1e-90|299|mmu:22428|dynactin 6 GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0003824//catalytic activity GO:0002478;GO:0006629//lipid metabolic process;GO:0006996//organelle organization;GO:0006629//lipid metabolic process;GO:0006996//organelle organization;GO:0006629//lipid metabolic process;GO:0006996//organelle organization;GO:0002478;GO:0006629//lipid metabolic process;GO:0006996//organelle organization gi|657406256|ref|NP_001280687.1|/2.88394e-93/dynactin subunit 6 isoform 3 [Mus musculus] 67869 1424 74.94333333 83.34666667 0.153324354 Up 0.354122005 Paip2 polyadenylate-binding protein-interacting protein 2 - GO:0044424 GO:0045182//translation regulator activity;GO:0003729//mRNA binding GO:0006413//translational initiation "gi|148664717|gb|EDK97133.1|/5.35619e-45/polyadenylate-binding protein-interacting protein 2, isoform CRA_b, partial [Mus musculus]" 52335 7526 3.606666667 2.86 -0.334650946 Down 0.354112603 Atxn1l ataxin 1-like "K14718|1|1e-24|119|bfo:BRAFLDRAFT_68432|solute carrier family 39 (zinc transporter), member 12" GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|124286823|ref|NP_001074399.1|/0/ataxin-1-like [Mus musculus] 226861 2835 0.97 1.456666667 0.586614127 Up 0.354093798 Hhat hedgehog acyltransferase - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle "GO:0032550;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups" GO:0007166//cell surface receptor signaling pathway;GO:0006497//protein lipidation;GO:0032502//developmental process gi|672075334|ref|XP_008768116.1|/0/PREDICTED: LOW QUALITY PROTEIN: protein-cysteine N-palmitoyltransferase HHAT isoform X2 [Rattus norvegicus] 268807 2212 39 34.87333333 -0.161349855 Down 0.354056189 Klhl38 kelch-like 38 K13959|1|0.0|1177|mmu:268807|kelch-like protein 38 - - - "gi|148697356|gb|EDL29303.1|/0/RIKEN cDNA 8230402K04, partial [Mus musculus]" 319518 2904 2.093333333 1.526666667 -0.455416961 Down 0.353886946 Pdpr pyruvate dehydrogenase phosphatase regulatory subunit K17509|1|0.0|1681|mmu:319518|pyruvate dehydrogenase phosphatase regulatory subunit GO:0043231//intracellular membrane-bounded organelle GO:0008168//methyltransferase activity GO:0006544//glycine metabolic process gi|37360608|dbj|BAC98282.1|/0/mKIAA1990 protein [Mus musculus] 246782 1885 21.81666667 24.61666667 0.174204729 Up 0.353877543 Atpaf2 ATP synthase mitochondrial F1 complex assembly factor 2 K07556|1|7e-155|550|mmu:246782|ATP synthase mitochondrial F1 complex assembly factor 2 GO:0043231//intracellular membrane-bounded organelle - GO:0070071 gi|238776839|ref|NP_663402.2|/5.97968e-154/ATP synthase mitochondrial F1 complex assembly factor 2 [Mus musculus] 20016 1305 10.78333333 12.38 0.199208103 Up 0.353849336 Polr1c polymerase (RNA) I polypeptide C K03027|1|0.0|689|mmu:20016|DNA-directed RNA polymerases I and III subunit RPAC1 GO:0044452//nucleolar part GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity;GO:0005515//protein binding GO:0006383//transcription from RNA polymerase III promoter;GO:0006360//transcription from RNA polymerase I promoter gi|120538451|gb|AAI30019.1|/0/Polr1c protein [Mus musculus] 20907 2245 1 1.49 0.575312331 Up 0.353792922 Stx1a syntaxin 1A (brain) K04560|1|1e-133|409|hgl:101701572|syntaxin 1A - - - - 70123 856 15.20666667 13.37 -0.18570448 Down 0.35378352 2210013O21Rik RIKEN cDNA 2210013O21 gene - - - - "gi|148699394|gb|EDL31341.1|/1.03655e-72/mCG1034286, isoform CRA_a, partial [Mus musculus]" 245666 5551.45 15.25 13.41333333 -0.185141438 Down 0.35378352 Iqsec2 IQ motif and Sec7 domain 2 K12495|1|0.0|2044|hsa:23096|IQ motif and SEC7 domain-containing protein - - - - 16421 2696 0.233333333 0.57 1.288569498 Up 0.353698898 Itgb7 integrin beta 7 K06590|1|0.0|1568|mmu:16421|integrin beta 7 - - - gi|160708008|ref|NP_038594.2|/0/integrin beta-7 precursor [Mus musculus] 228875 1951.37 9.116666667 10.53666667 0.208840202 Up 0.353651886 Slc35c2 "solute carrier family 35, member C2" "K15280|1|2e-146|522|mmu:228875|solute carrier family 35, member C2" GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane - GO:0007219//Notch signaling pathway;GO:0010467//gene expression;GO:0006493//protein O-linked glycosylation;GO:0007219//Notch signaling pathway;GO:0010467//gene expression;GO:0006493//protein O-linked glycosylation;GO:0007219//Notch signaling pathway;GO:0010467//gene expression;GO:0006493//protein O-linked glycosylation;GO:0007219//Notch signaling pathway;GO:0010467//gene expression;GO:0006493//protein O-linked glycosylation;GO:0007219//Notch signaling pathway;GO:0010467//gene expression;GO:0006493//protein O-linked glycosylation gi|537151296|gb|ERE71573.1|/1.37223e-154/solute carrier family 35 member C2 [Cricetulus griseus] 56878 2573.86 10.67 9.246666667 -0.206554889 Down 0.353651886 Rbms1 "RNA binding motif, single stranded interacting protein 1" K13208|1|9e-21|105|dre:431719|ELAV like protein 2/3/4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process;GO:0006259//DNA metabolic process "gi|213513205|ref|NP_001135404.1|/0/RNA-binding motif, single-stranded-interacting protein 1 isoform 1 [Mus musculus]" 66510 1397 34.29666667 38.34333333 0.160907395 Up 0.353539058 Rnf181 ring finger protein 181 K11982|1|9e-16|87.4|mze:101465256|E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27] - GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0032446//protein modification by small protein conjugation gi|47059206|ref|NP_079883.3|/1.10593e-95/E3 ubiquitin-protein ligase RNF181 [Mus musculus] 75913 1461 1.683333333 1.163333333 -0.533056351 Down 0.353463838 4930579G18Rik RIKEN cDNA 4930579G18 gene "K12875|1|1e-06|57.0|mmu:56215|apoptotic chromatin condensation inducer in the nucleus;K03847|2|8e-06|40.0|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - - 26379 2264 74.31333333 82.21333333 0.145751306 Up 0.353426229 Esrra "estrogen related receptor, alpha" K08552|1|1e-178|595|ocu:103347399|estrogen-related receptor alpha - - - gi|918596673|ref|XP_005384657.2|/5.24493e-178/PREDICTED: steroid hormone receptor ERR1 [Chinchilla lanigera] 66079 1059 5.353333333 6.383333333 0.253872499 Up 0.353416827 Tmem42 transmembrane protein 42 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|258679457|ref|NP_001158295.1|/1.82325e-52/transmembrane protein 42 isoform 2 [Mus musculus] 100041840 1573 0.213333333 0.01 -4.415037499 Down 0.353369815 Gm10408 predicted gene 10408 "K03844|1|3e-22|109|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - gi|755547000|ref|XP_011243064.1|/4.44888e-120/PREDICTED: alpha28-takusan isoform X2 [Mus musculus] 105242399 1546 0.213333333 0.01 -4.415037499 Down 0.353369815 LOC105242399 spermatogenesis associated glutamate (E)-rich protein-like - - - - gi|882938979|ref|NP_001297379.1|/1.06964e-118/spermatogenesis associated glutamate (E)-rich protein-like [Mus musculus] 20303 674 0.01 0.213333333 4.415037499 Up 0.353369815 Ccl4 chemokine (C-C motif) ligand 4 K12964|1|1e-37|158|mmu:20303|C-C motif chemokine 4 GO:0044421 GO:0005125//cytokine activity;GO:0048020//CCR chemokine receptor binding GO:0006816//calcium ion transport;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0032897//negative regulation of viral transcription;GO:0001819//positive regulation of cytokine production;GO:0019722//calcium-mediated signaling;GO:0043114//regulation of vascular permeability;GO:0006952//defense response gi|7305459|ref|NP_038680.1|/7.23957e-37/C-C motif chemokine 4 precursor [Mus musculus] 628705 1590 0.01 0.213333333 4.415037499 Up 0.353369815 Phf11c PHD finger protein 11C K18494|1|8e-173|609|mmu:107303348|histone-lysine N-methyltransferase SETDB2 [EC:2.1.1.43];K09188|5|2e-07|59.7|bmy:Bm1_21795|histone-lysine N-methyltransferase MLL3 [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|256223290|ref|NP_001157761.1|/0/PHD finger protein 11 family member [Mus musculus] 234199 1120 0.01 0.21 4.392317423 Up 0.353369815 Fgl1 fibrinogen-like protein 1 K03905|1|3e-57|224|xtr:100038189|fibrinogen gamma chain - - - - 545652 1556 0.21 0.01 -4.392317423 Down 0.353369815 Gm13275 predicted gene 13275 K05414|1|1e-37|160|cge:100763520|interferon alpha - - - - 244218 900 0.01 0.21 4.392317423 Up 0.353369815 Ctf2 cardiotrophin 2 K05422|1|1e-11|72.8|pss:106732763|cardiotrophin 1;K05421|3|2e-10|68.9|lcm:102364016|B-cell stimulating factor 3 GO:0044421 GO:0005126//cytokine receptor binding GO:0032502//developmental process;GO:0008283//cell proliferation gi|38524598|ref|NP_942155.1|/3.38385e-77/cardiotrophin-2 precursor [Mus musculus] 16952 1395 15.19666667 13.36666667 -0.185115173 Down 0.353360412 Anxa1 annexin A1 K17091|1|0.0|676|mmu:16952|annexin A1 GO:0005856//cytoskeleton;GO:0032991//macromolecular complex;GO:0005740//mitochondrial envelope;GO:0044459;GO:0031988//membrane-bounded vesicle;GO:0044421 GO:0005543//phospholipid binding;GO:0046872//metal ion binding;GO:0004859//phospholipase inhibitor activity;GO:0043566//structure-specific DNA binding;GO:0042802//identical protein binding;GO:0003723//RNA binding GO:0031016//pancreas development;GO:0006906//vesicle fusion;GO:0034614//cellular response to reactive oxygen species;GO:0051384//response to glucocorticoid;GO:0030072//peptide hormone secretion;GO:0001889//liver development;GO:0030217//T cell differentiation;GO:0022008//neurogenesis;GO:0007165//signal transduction;GO:0048771//tissue remodeling;GO:0001516//prostaglandin biosynthetic process;GO:0002526//acute inflammatory response;GO:0010212//response to ionizing radiation;GO:0043627//response to estrogen;GO:0001781//neutrophil apoptotic process;GO:0022602//ovulation cycle process;GO:0044092//negative regulation of molecular function;GO:0008283//cell proliferation;GO:0006464//cellular protein modification process;GO:0009913//epidermal cell differentiation;GO:0034097//response to cytokine;GO:0015909//long-chain fatty acid transport;GO:0009306//protein secretion gi|74183811|dbj|BAE24494.1|/0/unnamed protein product [Mus musculus] 56541 2584 34.46666667 38.48333333 0.159031987 Up 0.3533134 Habp4 hyaluronic acid binding protein 4 K19019|1|4e-143|511|mmu:56541|intracellular hyaluronan-binding protein 4 - - - - 110521 8753 4.67 3.82 -0.289849912 Down 0.353275791 Hivep1 human immunodeficiency virus type I enhancer binding protein 1 K09239|1|0.0|4717|mmu:110521|human immunodeficiency virus type I enhancer-binding protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding GO:0006366//transcription from RNA polymerase II promoter gi|117938312|ref|NP_031798.2|/0/zinc finger protein 40 [Mus musculus] 74103 2980 4.7 3.853333333 -0.286553765 Down 0.353275791 Nebl nebulette K18267|1|1e-60|238|xma:102236960|nebulin GO:0031674//I band;GO:0032432//actin filament bundle GO:0046914//transition metal ion binding;GO:0003779//actin binding GO:0007015//actin filament organization gi|62088202|dbj|BAD92548.1|/2.08318e-162/nebulette non-muscle isoform variant [Homo sapiens] 78703 883 76.21333333 68.47 -0.154571403 Down 0.353191169 C330013J21Rik zinc finger protein 972 K09228|1|2e-13|78.6|mmu:71508|KRAB domain-containing zinc finger protein - - - - 78308 2148.53 21.68333333 24.43 0.172067307 Up 0.35311595 Gpr108 G protein-coupled receptor 108 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148706303|gb|EDL38250.1|/0/G protein-coupled receptor 108, isoform CRA_c, partial [Mus musculus]" 72083 1010 8.796666667 10.20666667 0.214482932 Up 0.353087743 Mzt2 mitotic spindle organizing protein 2 K16574|1|1e-73|279|mmu:72083|mitotic-spindle organizing protein 2A/2B GO:0000931//gamma-tubulin large complex - - "gi|148664988|gb|EDK97404.1|/3.05176e-96/RIKEN cDNA 2410018G20, isoform CRA_a, partial [Mus musculus]" 20514 2758 10.75666667 12.33666667 0.197721558 Up 0.353003122 Slc1a5 "solute carrier family 1 (neutral amino acid transporter), member 5" "K05616|1|0.0|890|mmu:20514|solute carrier family 1 (neutral amino acid transporter), member 5" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0015291//secondary active transmembrane transporter activity;GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0016597//amino acid binding;GO:0015179//L-amino acid transmembrane transporter activity GO:0006858//extracellular transport;GO:0015807//L-amino acid transport gi|114326474|ref|NP_033227.2|/0/neutral amino acid transporter B(0) [Mus musculus] 58244 2459 6.056666667 7.146666667 0.238746486 Up 0.352946707 Stx6 syntaxin 6 K08498|1|7e-115|417|mmu:58244|syntaxin 6 GO:0005768//endosome;GO:0043234//protein complex;GO:0031224//intrinsic component of membrane;GO:0005802//trans-Golgi network GO:0005515//protein binding GO:0016192//vesicle-mediated transport;GO:0006996//organelle organization;GO:0015031//protein transport gi|74195867|dbj|BAE30494.1|/6.39334e-114/unnamed protein product [Mus musculus] 24068 979 33.31333333 37.27333333 0.162044127 Up 0.3529185 Sra1 steroid receptor RNA activator 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003676//nucleic acid binding;GO:0005102//receptor binding;GO:0003713//transcription coactivator activity;GO:0030546//receptor activator activity;GO:0003676//nucleic acid binding;GO:0005102//receptor binding;GO:0003713//transcription coactivator activity;GO:0030546//receptor activator activity;GO:0003676//nucleic acid binding;GO:0005102//receptor binding;GO:0003713//transcription coactivator activity;GO:0030546//receptor activator activity GO:0012501//programmed cell death;GO:0048869//cellular developmental process;GO:0006366//transcription from RNA polymerase II promoter;GO:0012501//programmed cell death;GO:0048869//cellular developmental process;GO:0006366//transcription from RNA polymerase II promoter;GO:0012501//programmed cell death;GO:0048869//cellular developmental process;GO:0006366//transcription from RNA polymerase II promoter gi|257096048|ref|NP_079567.2|/2.32748e-105/steroid receptor RNA activator 1 isoform a [Mus musculus] 19244 3406.44 68.09 75.67666667 0.15240561 Up 0.352880891 Ptp4a2 protein tyrosine phosphatase 4a2 K18041|1|3e-95|353|pale:102894358|protein tyrosine phosphatase type IVA [EC:3.1.3.48] GO:0005768//endosome;GO:0016020//membrane;GO:0005768//endosome;GO:0016020//membrane GO:0004725//protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity GO:0006470//protein dephosphorylation;GO:0006470//protein dephosphorylation "gi|440896935|gb|ELR48726.1|/6.71787e-96/Protein tyrosine phosphatase type IVA 2, partial [Bos mutus]" 83456 4053 16.60666667 18.77666667 0.17717845 Up 0.352862086 Mov10l1 Moloney leukemia virus 10-like 1 K13983|1|0.0|2313|mmu:83456|putative helicase MOV10L1 [EC:3.6.4.13] - - - gi|568993663|ref|XP_006521618.1|/0/PREDICTED: putative helicase Mov10l1 isoform X1 [Mus musculus] 13353 1359.75 21.74333333 24.47 0.170440974 Up 0.352833879 Dgcr6 DiGeorge syndrome critical region gene 6 K06262|1|2e-06|41.2|cjc:100896535|platelet glycoprotein Ib beta chain - - - "gi|148665084|gb|EDK97500.1|/7.45609e-89/DiGeorge syndrome critical region gene 6, isoform CRA_c [Mus musculus]" 216440 3961.01 21.55666667 24.27333333 0.17123813 Up 0.352683441 Os9 amplified in osteosarcoma K10088|1|0.0|1054|mmu:216440|protein OS-9 GO:0044432;GO:0044432 GO:0019899//enzyme binding;GO:0019899//enzyme binding GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0035437//maintenance of protein localization in endoplasmic reticulum;GO:0033554//cellular response to stress;GO:0016567//protein ubiquitination;GO:0006886//intracellular protein transport;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0035437//maintenance of protein localization in endoplasmic reticulum;GO:0033554//cellular response to stress;GO:0016567//protein ubiquitination;GO:0006886//intracellular protein transport gi|283837907|ref|NP_808282.2|/0/protein OS-9 isoform 2 precursor [Mus musculus] 12492 4729 32.97 36.88666667 0.161945536 Up 0.352617624 Scarb2 "scavenger receptor class B, member 2" K12384|1|0.0|940|mmu:12492|lysosome membrane protein 2 - - - - 75620 1236 73.60666667 66.19666667 -0.153077867 Down 0.352617624 Kxd1 KxDL motif containing 1 - GO:0031082 - GO:0006810//transport "gi|148696891|gb|EDL28838.1|/3.19866e-96/mCG140604, isoform CRA_c, partial [Mus musculus]" 17113 2258 22.02333333 24.72 0.166645899 Up 0.352495393 M6pr "mannose-6-phosphate receptor, cation dependent" K10089|1|4e-156|554|mmu:17113|cation-dependent mannose-6-phosphate receptor GO:0005768//endosome;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane GO:0015149//hexose transmembrane transporter activity;GO:0048029//monosaccharide binding GO:0008645//hexose transport;GO:0015031//protein transport gi|14916479|ref|NP_034879.2|/3.02817e-155/cation-dependent mannose-6-phosphate receptor precursor [Mus musculus] 72098 2605 1.796666667 2.4 0.417711634 Up 0.352420174 Tmem68 transmembrane protein 68 - GO:0031224//intrinsic component of membrane GO:0016740//transferase activity - gi|21312456|ref|NP_082373.1|/0/transmembrane protein 68 [Mus musculus] 242506 3977 0.416666667 0.81 0.959028219 Up 0.352373162 Frmd3 FERM domain containing 3 K06107|1|1e-60|238|cjc:100400936|erythrocyte membrane protein band 4.1 GO:0031224//intrinsic component of membrane;GO:0043232;GO:0031224//intrinsic component of membrane;GO:0043232 GO:0005515//protein binding;GO:0005515//protein binding - "gi|148699106|gb|EDL31053.1|/0/FERM domain containing 3, isoform CRA_a, partial [Mus musculus]" 100038392 1709 0.323333333 0.683333333 1.079567257 Up 0.352354357 Gm10785 predicted gene 10785 - - - - - 30931 1452 5.34 6.356666667 0.251430696 Up 0.35232615 Tor1a "torsin family 1, member A (torsin A)" "K01056|1|5e-25|118|tgu:100227249|peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]" GO:0044432;GO:0042995//cell projection;GO:0012506//vesicle membrane GO:0008092//cytoskeletal protein binding;GO:0032550 GO:0051084//'de novo' posttranslational protein folding;GO:0006998//nuclear envelope organization;GO:0051259//protein oligomerization;GO:0006950//response to stress gi|21450255|ref|NP_659133.1|/0/torsin-1A precursor [Mus musculus] 238024 2028 4.056666667 4.936666667 0.283242473 Up 0.352241528 Fn3krp fructosamine 3 kinase related protein K15523|1|1e-172|609|mmu:238024|protein-ribulosamine 3-kinase [EC:2.7.1.172] - "GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006796//phosphate-containing compound metabolic process gi|253970463|ref|NP_852085.2|/9.09372e-172/ketosamine-3-kinase [Mus musculus] 100503619 950 4.15 5.026666667 0.276490686 Up 0.352241528 E330011O21Rik RIKEN cDNA E330011O21 gene K06067|1|2e-45|105|lcm:102364559|histone deacetylase 1/2 [EC:3.5.1.98];K11404|5|5e-33|92.0|spu:590047|histone deacetylase 3 [EC:3.5.1.98] GO:0000118//histone deacetylase complex;GO:0000785//chromatin;GO:0044297//cell body GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0003676//nucleic acid binding;GO:0004407//histone deacetylase activity GO:0030326//embryonic limb morphogenesis;GO:2001141//regulation of RNA biosynthetic process;GO:0045687//positive regulation of glial cell differentiation;GO:0021543//pallium development;GO:0001942//hair follicle development;GO:0042476//odontogenesis;GO:0006979//response to oxidative stress;GO:0016575//histone deacetylation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030178//negative regulation of Wnt signaling pathway;GO:0043010//camera-type eye development;GO:0042221//response to chemical;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process gi|704567547|ref|XP_010184404.1|/4.25145e-47/PREDICTED: histone deacetylase 1 [Mesitornis unicolor] 242384 3562 0.01 0.206666667 4.36923381 Up 0.352166309 Lingo2 leucine rich repeat and Ig domain containing 2 K16360|1|2e-42|177|acs:100563545|netrin-G3 ligand GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|260268510|ref|NP_780725.2|/0/leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 precursor [Mus musculus] 666266 475 0.01 0.206666667 4.36923381 Up 0.352166309 Gm8013 predicted gene 8013 - - - - - 230027 2613 15.93 18.07333333 0.182116346 Up 0.35209109 Coq3 coenzyme Q3 methyltransferase K00591|1|0.0|699|mmu:230027|polyprenyldihydroxybenzoate methyltransferase / 3-demethylubiquinol 3-O-methyltransferase [EC:2.1.1.114 2.1.1.64] - - - - 21415 2855.77 15.77666667 17.92 0.183778216 Up 0.35209109 Tcf7l1 "transcription factor 7 like 1 (T cell specific, HMG box)" K04490|1|0.0|773|mmu:21415|transcription factor 7-like 1 - - - "gi|148666577|gb|EDK98993.1|/0/transcription factor 3, isoform CRA_c [Mus musculus]" 68371 1956 0.616666667 1.043333333 0.758637386 Up 0.352015871 Pbld1 phenazine biosynthesis-like protein domain containing 1 - - GO:0003824//catalytic activity GO:0008152//metabolic process gi|568968365|ref|XP_006514094.1|/5.27969e-153/PREDICTED: phenazine biosynthesis-like domain-containing protein 1 isoform X4 [Mus musculus] 13619 3762.34 6.933333333 5.853333333 -0.244290683 Down 0.351978262 Phc1 polyhomeotic-like 1 (Drosophila) K11456|1|0.0|1096|mmu:13619|polyhomeotic-like protein 1 GO:0044451;GO:0031519//PcG protein complex;GO:0044451;GO:0031519//PcG protein complex;GO:0044451;GO:0031519//PcG protein complex;GO:0044451;GO:0031519//PcG protein complex GO:0046872//metal ion binding;GO:0005488//binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0032526//response to retinoic acid;GO:0032526//response to retinoic acid;GO:0032526//response to retinoic acid;GO:0032526//response to retinoic acid gi|568940581|ref|XP_006505562.1|/0/PREDICTED: polyhomeotic-like protein 1 isoform X2 [Mus musculus] 18221 1363 67.08333333 74.19333333 0.145335181 Up 0.351968859 Nudc nudC nuclear distribution protein - GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton - GO:0009725//response to hormone;GO:0040023//establishment of nucleus localization;GO:0000087//mitotic M phase gi|6754910|ref|NP_035078.1|/3.75894e-149/nuclear migration protein nudC [Mus musculus] 14226 1007 0.64 0.286666667 -1.158697746 Down 0.351950055 Fkbp1b FK506 binding protein 1b K09568|1|6e-57|223|mmu:14226|FK506-binding protein 1 [EC:5.2.1.8] - - - gi|123173728|ref|NP_058559.3|/5.23908e-56/peptidyl-prolyl cis-trans isomerase FKBP1B [Mus musculus] 66235 926 36.17666667 32.36333333 -0.160699275 Down 0.3517338 Eif1ax "eukaryotic translation initiation factor 1A, X-linked" K03236|1|1e-50|202|cmk:103177512|translation initiation factor 1A GO:0044444//cytoplasmic part "GO:0008135//translation factor activity, RNA binding" GO:0006412//translation "gi|527266941|ref|XP_005151620.1|/1.673e-50/PREDICTED: eukaryotic translation initiation factor 1A, X-chromosomal [Melopsittacus undulatus]" 22169 3215 5.72 4.773333333 -0.26101806 Down 0.3517338 Cmpk2 "cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial" "K13809|1|0.0|823|mmu:22169|UMP-CMP kinase 2, mitochondrial [EC:2.7.4.14]" GO:0031981//nuclear lumen GO:0009041//uridylate kinase activity GO:0009197 "gi|117606366|ref|NP_065582.3|/0/UMP-CMP kinase 2, mitochondrial precursor [Mus musculus]" 56277 2698 0.683333333 1.123333333 0.717124682 Up 0.351724397 Tmem45a transmembrane protein 45a - GO:0016021//integral component of membrane - - gi|31542278|ref|NP_062605.2|/1.20214e-153/transmembrane protein 45A [Mus musculus] 18391 1578.18 12.44333333 14.22 0.192548457 Up 0.351667983 Sigmar1 sigma non-opioid intracellular receptor 1 - GO:0043005//neuron projection;GO:0031965//nuclear membrane;GO:0016021//integral component of membrane;GO:0019866//organelle inner membrane;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0031965//nuclear membrane;GO:0019866//organelle inner membrane;GO:0044444//cytoplasmic part;GO:0043005//neuron projection;GO:0031965//nuclear membrane;GO:0016021//integral component of membrane;GO:0019866//organelle inner membrane;GO:0044444//cytoplasmic part;GO:0031965//nuclear membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system;GO:0043005//neuron projection;GO:0031965//nuclear membrane;GO:0016021//integral component of membrane;GO:0019866//organelle inner membrane;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system "GO:0005488//binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds;GO:0008528//G-protein coupled peptide receptor activity;GO:0005488//binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds;GO:0008528//G-protein coupled peptide receptor activity;GO:0005488//binding;GO:0008528//G-protein coupled peptide receptor activity;GO:0005488//binding;GO:0008528//G-protein coupled peptide receptor activity;GO:0005488//binding;GO:0008528//G-protein coupled peptide receptor activity;GO:0005488//binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds;GO:0008528//G-protein coupled peptide receptor activity;GO:0005488//binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds;GO:0008528//G-protein coupled peptide receptor activity;GO:0005488//binding;GO:0008528//G-protein coupled peptide receptor activity" GO:0048731//system development;GO:0008204//ergosterol metabolic process;GO:0042981//regulation of apoptotic process;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0007186//G-protein coupled receptor signaling pathway;GO:0048731//system development;GO:0008204//ergosterol metabolic process;GO:0042981//regulation of apoptotic process;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0007186//G-protein coupled receptor signaling pathway;GO:0048731//system development;GO:0008204//ergosterol metabolic process;GO:0042981//regulation of apoptotic process;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0007186//G-protein coupled receptor signaling pathway;GO:0048731//system development;GO:0008204//ergosterol metabolic process;GO:0042981//regulation of apoptotic process;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0007186//G-protein coupled receptor signaling pathway;GO:0048731//system development;GO:0008204//ergosterol metabolic process;GO:0042981//regulation of apoptotic process;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0007186//G-protein coupled receptor signaling pathway;GO:0048731//system development;GO:0008204//ergosterol metabolic process;GO:0042981//regulation of apoptotic process;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0007186//G-protein coupled receptor signaling pathway;GO:0048731//system development;GO:0008204//ergosterol metabolic process;GO:0042981//regulation of apoptotic process;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0007186//G-protein coupled receptor signaling pathway;GO:0048731//system development;GO:0008204//ergosterol metabolic process;GO:0042981//regulation of apoptotic process;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0007186//G-protein coupled receptor signaling pathway gi|557786229|ref|NP_001273468.1|/6.51944e-100/sigma non-opioid intracellular receptor 1 isoform 3 [Mus musculus] 68098 2020.45 13 14.78 0.185134646 Up 0.351667983 Rchy1 ring finger and CHY zinc finger domain containing 1 K10144|1|3e-135|484|mmu:68098|RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27] GO:0043234//protein complex;GO:0016604//nuclear body;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0019787//ubiquitin-like protein transferase activity GO:0016567//protein ubiquitination;GO:0031331;GO:0016567//protein ubiquitination;GO:0031331;GO:0016567//protein ubiquitination;GO:0031331 gi|13386058|ref|NP_080833.1|/2.57189e-134/RING finger and CHY zinc finger domain-containing protein 1 isoform 1 [Mus musculus] 66403 2192 4.396666667 5.306666667 0.271395771 Up 0.351649178 Asf1a anti-silencing function 1A histone chaperone K10753|1|1e-114|416|mmu:66403|histone chaperone ASF1 GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding GO:0001503//ossification;GO:0006259//DNA metabolic process;GO:0006342//chromatin silencing;GO:0030154//cell differentiation;GO:0034728//nucleosome organization gi|13384964|ref|NP_079817.1|/9.49477e-114/histone chaperone ASF1A [Mus musculus] 16156 1845 2.28 2.936666667 0.365145694 Up 0.351602166 Il11 interleukin 11 K05417|1|4e-77|291|mmu:16156|interleukin 11 GO:0044424;GO:0044421;GO:0044424;GO:0044421 GO:0005126//cytokine receptor binding;GO:0005126//cytokine receptor binding GO:0001934//positive regulation of protein phosphorylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0046879//hormone secretion;GO:0008283//cell proliferation;GO:0000165//MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0046879//hormone secretion;GO:0008283//cell proliferation;GO:0000165//MAPK cascade gi|74215582|dbj|BAE21410.1|/3.04903e-76/unnamed protein product [Mus musculus] 52668 1036.81 31.45 35.24333333 0.164290364 Up 0.351564557 Ifi27 "interferon, alpha-inducible protein 27" - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0010033//response to organic substance;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0010033//response to organic substance;GO:0006915//apoptotic process;GO:0007165//signal transduction "gi|148686883|gb|EDL18830.1|/2.02941e-106/DNA segment, Chr 12, ERATO Doi 647, expressed, isoform CRA_c, partial [Mus musculus]" 68497 5476 8.736666667 10.11333333 0.211103732 Up 0.351526947 Arel1 apoptosis resistant E3 ubiquitin protein ligase 1 K10591|1|3e-57|227|isc:IscW_ISCW021604|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26];K13305|5|4e-56|223|xma:102218091|E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26] - - - gi|26006143|dbj|BAC41414.1|/0/mKIAA0317 protein [Mus musculus] 56200 4763 10.29666667 8.92 -0.207061755 Down 0.351526947 Ddx21 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 K16911|1|0.0|1401|mmu:56200|ATP-dependent RNA helicase DDX21 [EC:3.6.4.13] GO:0031981//nuclear lumen "GO:0004386//helicase activity;GO:0003723//RNA binding;GO:0042623//ATPase activity, coupled;GO:0032550" GO:0051707//response to other organism;GO:0043331//response to dsRNA gi|72384374|ref|NP_062426.2|/0/nucleolar RNA helicase 2 [Mus musculus] 68209 646 15.77666667 17.89 0.181360966 Up 0.351442326 Rnaseh2c "ribonuclease H2, subunit C" K10745|1|1e-92|341|mmu:68209|ribonuclease H2 subunit C GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0016070//RNA metabolic process gi|13386102|ref|NP_080892.1|/7.17013e-92/ribonuclease H2 subunit C [Mus musculus] 224694 2253 0.7 0.336666667 -1.056034035 Down 0.351404716 Zfp81 zinc finger protein 81 K09228|1|0.0|1149|mmu:224694|KRAB domain-containing zinc finger protein - - - gi|126432560|ref|NP_997424.1|/0/zinc finger protein 81 [Mus musculus] 14394 4702 0.333333333 0.066666667 -2.321928095 Down 0.351404716 Gabra1 "gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1" K05175|1|0.0|894|ecb:100070870|gamma-aminobutyric acid receptor subunit alpha GO:0097060//synaptic membrane;GO:0034702//ion channel complex GO:0030594//neurotransmitter receptor activity;GO:0005253//anion channel activity;GO:0005488//binding;GO:0005230//extracellular ligand-gated ion channel activity;GO:0004888//transmembrane signaling receptor activity GO:0015698//inorganic anion transport;GO:0007270//neuron-neuron synaptic transmission;GO:0007186//G-protein coupled receptor signaling pathway gi|524939541|ref|XP_005071994.1|/0/PREDICTED: gamma-aminobutyric acid receptor subunit alpha-1 isoform X1 [Mesocricetus auratus] 233908 1845 62.39 69.19 0.149248731 Up 0.35130129 Fus fused in sarcoma K13098|1|7e-75|284|mmu:233908|RNA-binding protein FUS GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding - "gi|148685673|gb|EDL17620.1|/5.94148e-74/fusion, derived from t(12;16) malignant liposarcoma (human), isoform CRA_f, partial [Mus musculus]" 240263 2866 3.736666667 2.99 -0.321606388 Down 0.35130129 Fem1c fem-1 homolog c (C.elegans) K10349|1|3e-111|405|mdo:100018974|Fem-1 homolog b GO:0044424 - GO:0032446//protein modification by small protein conjugation gi|27734132|ref|NP_775599.1|/0/protein fem-1 homolog C [Mus musculus] 319673 2740.88 2.49 3.183333333 0.35439249 Up 0.351226071 9330159M07Rik RIKEN cDNA 9330159M07 gene K12019|1|4e-38|162|mmu:666731|tripartite motif-containing protein 43/48/49/64/77 - - - - 100859931 3835 1.273333333 1.806666667 0.504720213 Up 0.351226071 Gm20604 predicted gene 20604 K17561|1|2e-17|94.4|cge:103164277|coiled-coil domain-containing protein 8;K02183|4|3e-11|74.3|umr:103657204|calmodulin GO:0044424 GO:0042802//identical protein binding GO:0006921//cellular component disassembly involved in execution phase of apoptosis gi|11612503|ref|NP_071718.1|/0/modulator of apoptosis 1 [Mus musculus] 100316727 95 0.423333333 0.81 0.936127817 Up 0.351188461 Mir2139 microRNA 2139 - - - - - 57376 2961 20.74333333 23.35333333 0.170980742 Up 0.351179059 Smarce1 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1" "K11651|1|7e-173|610|mmu:57376|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1" GO:0090544//BAF-type complex;GO:0031981//nuclear lumen;GO:0005694//chromosome GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0016407//acetyltransferase activity;GO:0005102//receptor binding GO:0016568//chromatin modification;GO:0048731//system development;GO:0034728//nucleosome organization;GO:0006366//transcription from RNA polymerase II promoter gi|568975009|ref|XP_006533888.1|/6.40698e-172/PREDICTED: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X1 [Mus musculus] 75613 2291 59.58 66.31333333 0.154470852 Up 0.351169657 Med25 mediator complex subunit 25 K15168|1|0.0|1024|mmu:75613|mediator of RNA polymerase II transcription subunit 25 - GO:0042974//retinoic acid receptor binding GO:0007050//cell cycle arrest;GO:0035561//regulation of chromatin binding;GO:0008285//negative regulation of cell proliferation;GO:0031334//positive regulation of protein complex assembly;GO:0006366//transcription from RNA polymerase II promoter gi|20149312|ref|NP_083641.1|/0/mediator of RNA polymerase II transcription subunit 25 [Mus musculus] 30878 3148 5.896666667 6.963333333 0.239878444 Up 0.351038023 Apln apelin K05225|1|2e-21|107|mmu:30878|apelin GO:0044421;GO:0044444//cytoplasmic part GO:0071855//neuropeptide receptor binding GO:0007585//respiratory gaseous exchange;GO:0008016//regulation of heart contraction;GO:0051458//corticotropin secretion;GO:0008283//cell proliferation;GO:0016310//phosphorylation;GO:0019229//regulation of vasoconstriction;GO:0042311//vasodilation;GO:0046887//positive regulation of hormone secretion;GO:0031649//heat generation;GO:0007631//feeding behavior;GO:0008217//regulation of blood pressure "gi|148697116|gb|EDL29063.1|/4.21654e-63/apelin, partial [Mus musculus]" 233890 2268 31.49 35.20666667 0.160954883 Up 0.351038023 Zfp768 zinc finger protein 768 K09228|1|0.0|1119|mmu:233890|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|22122751|ref|NP_666314.1|/0/zinc finger protein 768 [Mus musculus] 51796 3732 35.36333333 31.66666667 -0.159289256 Down 0.350943999 Srrm1 serine/arginine repetitive matrix 1 K13171|1|2e-66|257|mmu:51796|serine/arginine repetitive matrix protein 1 - - - gi|568931584|ref|XP_006539090.1|/1.77969e-65/PREDICTED: serine/arginine repetitive matrix protein 1 isoform X3 [Mus musculus] 76448 3185 15.87666667 17.96333333 0.178147038 Up 0.350943999 Ppp1r18 "protein phosphatase 1, regulatory subunit 18" K17559|1|0.0|950|mmu:76448|phostensin GO:0043232;GO:0043232;GO:0043232 GO:0008092//cytoskeletal protein binding;GO:0019899//enzyme binding;GO:0008092//cytoskeletal protein binding;GO:0019899//enzyme binding;GO:0008092//cytoskeletal protein binding;GO:0019899//enzyme binding - gi|569001983|ref|XP_006525156.1|/0/PREDICTED: phostensin isoform X2 [Mus musculus] 15976 1521.95 32.33 36.01666667 0.155791159 Up 0.350878183 Ifnar2 interferon (alpha and beta) receptor 2 K05131|1|0.0|882|mmu:15976|interferon receptor 2 GO:0016021//integral component of membrane;GO:0044421;GO:0016021//integral component of membrane;GO:0044421 GO:0019900//kinase binding;GO:0019961;GO:0004904//interferon receptor activity;GO:0019900//kinase binding;GO:0019961;GO:0004904//interferon receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0034097//response to cytokine;GO:0006366//transcription from RNA polymerase II promoter;GO:0019221//cytokine-mediated signaling pathway;GO:0006366//transcription from RNA polymerase II promoter gi|160358795|ref|NP_001103968.1|/6.26025e-131/interferon alpha/beta receptor 2 isoform b precursor [Mus musculus] 73419 2318 3.72 4.546666667 0.289506617 Up 0.350737147 Armt1 acidic residue methyltransferase 1 - - - - - 432763 1360 0.216666667 0.543333333 1.326360341 Up 0.350699537 Prr7 proline rich 7 (synaptic) - GO:0097060//synaptic membrane;GO:0031224//intrinsic component of membrane - - gi|71892426|ref|NP_001025467.1|/2.7545e-59/proline-rich protein 7 [Mus musculus] 13528 2453 1.68 1.166666667 -0.526068812 Down 0.350690135 Dtnb "dystrobrevin, beta" K10366|1|8e-50|201|obi:106873450|dystrophin GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - "gi|148669448|gb|EDL01395.1|/0/dystrobrevin, beta, isoform CRA_e, partial [Mus musculus]" 276846 2505 12.60666667 14.36 0.187868887 Up 0.350661928 Pigs "phosphatidylinositol glycan anchor biosynthesis, class S" "K05291|1|0.0|987|mmu:276846|phosphatidylinositol glycan, class S" GO:0030176//integral component of endoplasmic reticulum membrane GO:0016787//hydrolase activity GO:0006497//protein lipidation gi|41351529|ref|NP_958808.1|/0/GPI transamidase component PIG-S [Mus musculus] 223774 2131 4.786666667 5.726666667 0.258674287 Up 0.350661928 Alg12 "asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase)" "K03847|1|3e-140|501|pale:102883747|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane "GO:0000009//alpha-1,6-mannosyltransferase activity;GO:0000009//alpha-1,6-mannosyltransferase activity" GO:0006486//protein glycosylation;GO:0006497//protein lipidation;GO:0006486//protein glycosylation;GO:0006497//protein lipidation "gi|21703942|ref|NP_663452.1|/0/dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase isoform 2 [Mus musculus]" 74770 1870 57.18333333 63.65333333 0.154641346 Up 0.35051149 Hhatl hedgehog acyltransferase-like - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - GO:0006500;GO:0006500 gi|251823939|ref|NP_083371.2|/0/protein-cysteine N-palmitoyltransferase HHAT-like protein [Mus musculus] 14813 4895 0.343333333 0.706666667 1.041419927 Up 0.350417466 Grin2c "glutamate receptor, ionotropic, NMDA2C (epsilon 3)" "K05211|1|0.0|2230|mmu:14813|glutamate receptor ionotropic, NMDA 2C" GO:0030313//cell envelope;GO:0008328//ionotropic glutamate receptor complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0044424 GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004970//ionotropic glutamate receptor activity;GO:0019904//protein domain specific binding GO:0033036;GO:0009605//response to external stimulus;GO:0040011//locomotion;GO:0009895;GO:0051899//membrane depolarization;GO:0006811//ion transport;GO:0006950//response to stress;GO:0007215//glutamate receptor signaling pathway;GO:0050905//neuromuscular process "gi|568971676|ref|XP_006532298.1|/0/PREDICTED: glutamate receptor ionotropic, NMDA 2C isoform X2 [Mus musculus]" 72726 1843 5.366666667 6.366666667 0.24651195 Up 0.350379856 Tbcc tubulin-specific chaperone C K07374|1|6e-28|128|isc:IscW_ISCW017473|tubulin alpha;K18272|2|3e-21|106|myb:102243070|protein XRP2 - - - - 382014 3773 8.5 9.86 0.214124805 Up 0.350351649 Ano8 anoctamin 8 K19502|1|0.0|916|mmu:382014|anoctamin-8 GO:0016020//membrane;GO:0044464 GO:0005254//chloride channel activity - gi|50511029|dbj|BAD32500.1|/0/mKIAA1623 protein [Mus musculus] 217207 4344 6.826666667 5.763333333 -0.244277846 Down 0.350267028 Dhx8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 K12818|1|0.0|1882|mmu:217207|ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13] GO:0005681//spliceosomal complex "GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled" GO:0006396//RNA processing gi|149054338|gb|EDM06155.1|/0/DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Rattus norvegicus] 67844 2054 0.58 0.996666667 0.781058178 Up 0.350220016 Rab32 "RAB32, member RAS oncogene family" K07918|1|3e-126|454|mmu:67844|Ras-related protein Rab-32 GO:0030139//endocytic vesicle GO:0032550 GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization;GO:0006996//organelle organization gi|13385896|ref|NP_080681.1|/2.90999e-125/ras-related protein Rab-32 [Mus musculus] 260409 1967 12.03 13.76 0.193843828 Up 0.350125992 Cdc42ep3 CDC42 effector protein (Rho GTPase binding) 3 - GO:0005856//cytoskeleton GO:0008092//cytoskeletal protein binding GO:0050794//regulation of cellular process;GO:0007154//cell communication gi|13386006|ref|NP_080790.1|/1.91931e-102/cdc42 effector protein 3 [Mus musculus] 20439 2488 3.95 4.806666667 0.283184105 Up 0.350097785 Siah2 seven in absentia 2 K08742|1|4e-157|558|rno:140593|E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27] GO:0044297//cell body;GO:0005768//endosome;GO:0042995//cell projection GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity;GO:0044390//ubiquitin-like protein conjugating enzyme binding;GO:0019787//ubiquitin-like protein transferase activity GO:0030178//negative regulation of Wnt signaling pathway;GO:0016567//protein ubiquitination;GO:0006935//chemotaxis;GO:0019941//modification-dependent protein catabolic process;GO:0032502//developmental process;GO:0097191//extrinsic apoptotic signaling pathway;GO:0035556//intracellular signal transduction gi|40254613|ref|NP_033200.2|/3.07619e-156/E3 ubiquitin-protein ligase SIAH2 [Mus musculus] 72273 575 4.033333333 4.893333333 0.278844921 Up 0.350097785 Smim24 small integral membrane protein 24 - - - - gi|153791321|ref|NP_001093387.1|/8.17376e-29/small integral membrane protein 24 precursor [Mus musculus] 22138 82991.54 34.98333333 31.37 -0.157282232 Down 0.35007898 Ttn titin K12567|1|0.0|4.369e+04|mmu:22138|titin [EC:2.7.11.1] - - - - 104349 2041 0.346666667 0.706666667 1.027480736 Up 0.350003761 Zfp119a zinc finger protein 119a K09228|1|0.0|1202|mmu:104349|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|21536254|ref|NP_653129.1|/0/zinc finger protein 119a [Mus musculus] 78323 3025.82 8.536666667 7.32 -0.221829199 Down 0.349994359 Fam219b "family with sequence similarity 219, member B" - - - GO:0044710;GO:0006818//hydrogen transport;GO:0006811//ion transport;GO:0044710;GO:0006818//hydrogen transport;GO:0006811//ion transport gi|261599081|ref|NP_001159836.1|/3.99465e-76/protein FAM219B isoform 1 [Mus musculus] 12579 1393 0.18 0.503333333 1.483517237 Up 0.349975554 Cdkn2b "cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)" K04685|1|3e-68|261|mmu:12579|cyclin-dependent kinase inhibitor 2B GO:0043231//intracellular membrane-bounded organelle "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019900//kinase binding" GO:0000075//cell cycle checkpoint;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016310//phosphorylation;GO:0008285//negative regulation of cell proliferation;GO:0030099//myeloid cell differentiation;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0030855//epithelial cell differentiation;GO:0007584//response to nutrient "gi|159162196|pdb|1D9S|A/2.16661e-67/Chain A, Tumor Suppressor P15(Ink4b) Structure By Comparative Modeling And Nmr Data" 230770 1845 2.603333333 3.3 0.342105977 Up 0.349806311 Tmem39b transmembrane protein 39b K16531|1|2e-29|133|tsp:Tsp_10250|Bardet-Biedl syndrome 4 protein GO:0031224//intrinsic component of membrane - - "gi|148698217|gb|EDL30164.1|/0/transmembrane protein 39b, isoform CRA_b, partial [Mus musculus]" 13822 4338.77 11.51 10.00333333 -0.202407015 Down 0.349712287 Epb41l2 erythrocyte membrane protein band 4.1 like 2 K06107|1|0.0|1737|mmu:13822|erythrocyte membrane protein band 4.1 GO:0005856//cytoskeleton;GO:0043234//protein complex;GO:0044425;GO:0031981//nuclear lumen;GO:0005856//cytoskeleton;GO:0043234//protein complex;GO:0044425;GO:0031981//nuclear lumen GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding GO:0022604//regulation of cell morphogenesis;GO:0030036//actin cytoskeleton organization;GO:0022604//regulation of cell morphogenesis;GO:0030036//actin cytoskeleton organization gi|157041260|ref|NP_038539.2|/0/band 4.1-like protein 2 [Mus musculus] 69821 1330 11.45666667 9.95 -0.20341892 Down 0.349712287 Mterf4 mitochondrial transcription termination factor 4 "K15032|1|1e-169|598|mmu:69821|mTERF domain-containing protein, mitochondrial" GO:0043231//intracellular membrane-bounded organelle;GO:0000315//organellar large ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0000315//organellar large ribosomal subunit GO:0003723//RNA binding;GO:0003723//RNA binding GO:0000959//mitochondrial RNA metabolic process;GO:0001654//eye development;GO:0006605//protein targeting;GO:0042254//ribosome biogenesis;GO:0000959//mitochondrial RNA metabolic process;GO:0001654//eye development;GO:0006605//protein targeting;GO:0042254//ribosome biogenesis "gi|30017341|ref|NP_835152.1|/9.17599e-169/transcription termination factor 4, mitochondrial isoform 1 [Mus musculus]" 18952 1462.44 20.06333333 22.58 0.17048417 Up 0.349712287 4-Sep septin 4 K16943|1|0.0|608|mmu:18952|septin 4 GO:0032156//septin cytoskeleton;GO:0005929//cilium;GO:0032156//septin cytoskeleton;GO:0005929//cilium;GO:0032156//septin cytoskeleton;GO:0005929//cilium;GO:0032156//septin cytoskeleton;GO:0005929//cilium GO:0032550;GO:0032550;GO:0032550;GO:0032550 GO:0007417//central nervous system development;GO:0097193//intrinsic apoptotic signaling pathway;GO:0016567//protein ubiquitination;GO:0007281//germ cell development;GO:0007005//mitochondrion organization;GO:0007417//central nervous system development;GO:0097193//intrinsic apoptotic signaling pathway;GO:0016567//protein ubiquitination;GO:0007281//germ cell development;GO:0007005//mitochondrion organization;GO:0007417//central nervous system development;GO:0097193//intrinsic apoptotic signaling pathway;GO:0016567//protein ubiquitination;GO:0007281//germ cell development;GO:0007005//mitochondrion organization;GO:0007417//central nervous system development;GO:0097193//intrinsic apoptotic signaling pathway;GO:0016567//protein ubiquitination;GO:0007281//germ cell development;GO:0007005//mitochondrion organization gi|6755120|ref|NP_035259.1|/0/septin-4 isoform 1 [Mus musculus] 73261 1099 1.38 1.92 0.476438044 Up 0.34968408 1700037C18Rik RIKEN cDNA 1700037C18 gene - - - - gi|145864485|ref|NP_082760.2|/3.85969e-87/uncharacterized protein C16orf90 homolog [Mus musculus] 18596 5410.28 34.44 30.86666667 -0.15803545 Down 0.349665275 Pdgfrb "platelet derived growth factor receptor, beta polypeptide" K05089|1|0.0|2061|mmu:18596|platelet-derived growth factor receptor beta [EC:2.7.10.1] GO:0005764//lysosome;GO:0031982//vesicle;GO:0044459;GO:0016021//integral component of membrane;GO:0005764//lysosome;GO:0031982//vesicle;GO:0044459;GO:0016021//integral component of membrane GO:0032550;GO:0005017//platelet-derived growth factor-activated receptor activity;GO:0019838//growth factor binding;GO:0070851//growth factor receptor binding;GO:0032550;GO:0005017//platelet-derived growth factor-activated receptor activity;GO:0019838//growth factor binding;GO:0070851//growth factor receptor binding GO:0006023;GO:0006915//apoptotic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043405//regulation of MAP kinase activity;GO:0048534//hematopoietic or lymphoid organ development;GO:0008284//positive regulation of cell proliferation;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0048871//multicellular organismal homeostasis;GO:0048017//inositol lipid-mediated signaling;GO:0001501//skeletal system development;GO:0030239//myofibril assembly;GO:0043009//chordate embryonic development;GO:0010518//positive regulation of phospholipase activity;GO:0072049//comma-shaped body morphogenesis;GO:1900238;GO:0072104//glomerular capillary formation;GO:0072593//reactive oxygen species metabolic process;GO:0043410//positive regulation of MAPK cascade;GO:0035051//cardiocyte differentiation;GO:0072110//glomerular mesangial cell proliferation;GO:0034767//positive regulation of ion transmembrane transport;GO:0060537//muscle tissue development;GO:0035270//endocrine system development;GO:0006935//chemotaxis;GO:0035904//aorta development;GO:0006650//glycerophospholipid metabolic process;GO:0000302//response to reactive oxygen species;GO:0043627//response to estrogen;GO:0060973//cell migration involved in heart development;GO:0036119//response to platelet-derived growth factor;GO:0001570//vasculogenesis;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0010922//positive regulation of phosphatase activity;GO:0072050//S-shaped body morphogenesis;GO:0014909//smooth muscle cell migration;GO:0043583//ear development;GO:0007067//mitotic nuclear division;GO:0009611//response to wounding;GO:0006023;GO:0006915//apoptotic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043405//regulation of MAP kinase activity;GO:0048534//hematopoietic or lymphoid organ development;GO:0008284//positive regulation of cell proliferation;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0048871//multicellular organismal homeostasis;GO:0048017//inositol lipid-mediated signaling;GO:0001501//skeletal system development;GO:0030239//myofibril assembly;GO:0043009//chordate embryonic development;GO:0010518//positive regulation of phospholipase activity;GO:0072049//comma-shaped body morphogenesis;GO:1900238;GO:0072104//glomerular capillary formation;GO:0072593//reactive oxygen species metabolic process;GO:0043410//positive regulation of MAPK cascade;GO:0035051//cardiocyte differentiation;GO:0072110//glomerular mesangial cell proliferation;GO:0034767//positive regulation of ion transmembrane transport;GO:0060537//muscle tissue development;GO:0035270//endocrine system development;GO:0006935//chemotaxis;GO:0035904//aorta development;GO:0006650//glycerophospholipid metabolic process;GO:0000302//response to reactive oxygen species;GO:0043627//response to estrogen;GO:0060973//cell migration involved in heart development;GO:0036119//response to platelet-derived growth factor;GO:0001570//vasculogenesis;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0010922//positive regulation of phosphatase activity;GO:0072050//S-shaped body morphogenesis;GO:0014909//smooth muscle cell migration;GO:0043583//ear development;GO:0007067//mitotic nuclear division;GO:0009611//response to wounding "gi|148677841|gb|EDL09788.1|/0/platelet derived growth factor receptor, beta polypeptide, isoform CRA_b, partial [Mus musculus]" 666311 1996 4.73 5.663333333 0.259811263 Up 0.349618263 Zscan25 zinc finger and SCAN domain containing 25 K09229|1|0.0|1150|mmu:666311|KRAB and SCAN domains-containing zinc finger protein;K09230|2|0.0|1106|rno:363872|SCAN domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding "GO:0006351//transcription, DNA-templated" gi|124487459|ref|NP_001074900.1|/0/zinc finger and SCAN domain-containing protein 25 [Mus musculus] 18091 1524 55.26666667 61.43666667 0.152690342 Up 0.349608861 Nkx2-5 NK2 homeobox 5 K09345|1|5e-142|506|mmu:18091|homeobox protein Nkx-2.5 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle "GO:0044212//transcription regulatory region DNA binding;GO:0042802//identical protein binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0046983//protein dimerization activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding" GO:0003283//atrial septum development;GO:0002028//regulation of sodium ion transport;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0048534//hematopoietic or lymphoid organ development;GO:0043009//chordate embryonic development;GO:0007423//sensory organ development;GO:0008016//regulation of heart contraction;GO:0003207//cardiac chamber formation;GO:0003343;GO:0010002//cardioblast differentiation;GO:0003151//outflow tract morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010830//regulation of myotube differentiation;GO:0042127//regulation of cell proliferation;GO:0035270//endocrine system development;GO:0070848//response to growth factor;GO:0030182//neuron differentiation;GO:0003281//ventricular septum development;GO:0030178//negative regulation of Wnt signaling pathway;GO:1901021//positive regulation of calcium ion transmembrane transporter activity;GO:0055011//atrial cardiac muscle cell differentiation;GO:0003209//cardiac atrium morphogenesis;GO:0003165//Purkinje myocyte development;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006942//regulation of striated muscle contraction;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0043627//response to estrogen;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0003143//embryonic heart tube morphogenesis;GO:0010659//cardiac muscle cell apoptotic process;GO:0055003//cardiac myofibril assembly;GO:0014855;GO:0060922;GO:0003215//cardiac right ventricle morphogenesis gi|6679068|ref|NP_032726.1|/4.37792e-141/homeobox protein Nkx-2.5 [Mus musculus] 17449 1958 954.2333333 1050.086667 0.138094414 Up 0.349580654 Mdh1 "malate dehydrogenase 1, NAD (soluble)" K00025|1|1e-175|619|mmu:17449|malate dehydrogenase [EC:1.1.1.37] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0016615//malate dehydrogenase activity;GO:0000166//nucleotide binding;GO:0016615//malate dehydrogenase activity;GO:0000166//nucleotide binding GO:0043648//dicarboxylic acid metabolic process;GO:0005975//carbohydrate metabolic process;GO:0009060//aerobic respiration;GO:0019674//NAD metabolic process;GO:0043648//dicarboxylic acid metabolic process;GO:0005975//carbohydrate metabolic process;GO:0009060//aerobic respiration;GO:0019674//NAD metabolic process "gi|148675904|gb|EDL07851.1|/0/malate dehydrogenase 1, NAD (soluble), isoform CRA_c, partial [Mus musculus]" 547253 7251 2.98 3.72 0.319990291 Up 0.349561849 Parp14 "poly (ADP-ribose) polymerase family, member 14" K15261|1|0.0|3471|mmu:547253|poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30] - - - - 20892 655 31.19 34.74 0.155514201 Up 0.349552447 Stra13 stimulated by retinoic acid 13 K15360|1|1e-36|155|mmu:20892|centromere protein X "GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0000775//chromosome, centromeric region" GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process;GO:0000087//mitotic M phase;GO:0006974//cellular response to DNA damage stimulus gi|755537919|ref|XP_011247153.1|/6.43108e-59/PREDICTED: centromere protein X isoform X3 [Mus musculus] 15953 1793.72 2.446666667 3.123333333 0.352268985 Up 0.349543044 Ifi47 interferon gamma inducible protein 47 K17072|1|0.0|786|mmu:15953|interferon gamma inducible protein 47 - - GO:0006950//response to stress;GO:0006950//response to stress;GO:0006950//response to stress gi|6680359|ref|NP_032356.1|/0/interferon gamma inducible protein 47 [Mus musculus] 68152 2304 3.24 4.013333333 0.308807173 Up 0.349496032 Fam133b "family with sequence similarity 133, member B" - - - - "gi|148682654|gb|EDL14601.1|/5.6461e-48/mCG6108, isoform CRA_b, partial [Mus musculus]" 18746 2432 828.8866667 915.7833333 0.143831453 Up 0.34948663 Pkm "pyruvate kinase, muscle" K00873|1|0.0|1048|xla:100037030|pyruvate kinase [EC:2.7.1.40] GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0044444//cytoplasmic part GO:0016301//kinase activity;GO:0032550;GO:0031420;GO:0016301//kinase activity;GO:0032550;GO:0031420 GO:0042246//tissue regeneration;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006007//glucose catabolic process;GO:0006090//pyruvate metabolic process;GO:0009887//organ morphogenesis;GO:0008219//cell death;GO:0042246//tissue regeneration;GO:0014854//response to inactivity;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006007//glucose catabolic process;GO:0006090//pyruvate metabolic process;GO:0043434//response to peptide hormone;GO:0009628//response to abiotic stimulus;GO:0009887//organ morphogenesis;GO:0008219//cell death;GO:0031667//response to nutrient levels gi|564364019|ref|XP_006243249.1|/0/PREDICTED: pyruvate kinase PKM isoform X1 [Rattus norvegicus] 102209 1528 12.06333333 13.77 0.190899952 Up 0.349326789 Snapc2 "small nuclear RNA activating complex, polypeptide 2" K15209|1|0.0|718|mmu:102209|snRNA-activating protein complex subunit 2 GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated" gi|19527188|ref|NP_598729.1|/0/snRNA-activating protein complex subunit 2 [Mus musculus] 20218 3399.48 15.31333333 17.34666667 0.179870105 Up 0.349298582 Khdrbs1 "KH domain containing, RNA binding, signal transduction associated 1" "K13198|1|6e-153|544|mmu:20218|KH domain-containing, RNA-binding, signal transduction-associated protein 1" GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0030674//protein binding, bridging;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0030674//protein binding, bridging;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding" "GO:0006351//transcription, DNA-templated;GO:0006413//translational initiation;GO:0006396//RNA processing;GO:0022402//cell cycle process;GO:0007165//signal transduction;GO:0010608//posttranscriptional regulation of gene expression;GO:0006405//RNA export from nucleus;GO:0006351//transcription, DNA-templated;GO:0006413//translational initiation;GO:0006396//RNA processing;GO:0022402//cell cycle process;GO:0007165//signal transduction;GO:0010608//posttranscriptional regulation of gene expression;GO:0006405//RNA export from nucleus" "gi|110626031|ref|NP_035447.3|/4.84761e-152/KH domain-containing, RNA-binding, signal transduction-associated protein 1 [Mus musculus]" 66684 2256 8.716666667 7.506666667 -0.215604119 Down 0.34925157 Tceal8 transcription elongation factor A (SII)-like 8 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0008135//translation factor activity, RNA binding;GO:0008135//translation factor activity, RNA binding" "GO:0006351//transcription, DNA-templated;GO:0006412//translation;GO:0006351//transcription, DNA-templated;GO:0006412//translation" gi|31981215|ref|NP_079979.2|/2.46298e-56/transcription elongation factor A protein-like 8 [Mus musculus] 654801 2146 4.426666667 5.32 0.265205505 Up 0.349101132 Zfp784 zinc finger protein 784 K09228|1|3e-47|192|lcm:102357282|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|197386066|ref|NP_001128016.1|/9.768e-156/zinc finger protein 784 [Rattus norvegicus] 666907 996 4.353333333 5.246666667 0.269280644 Up 0.349101132 Ms4a4a "membrane-spanning 4-domains, subfamily A, member 4A" "K08090|1|5e-17|90.9|rno:25316|membrane-spanning 4-domains, subfamily A, member 2;K19928|5|1e-14|82.8|clv:102089886|zona pellucida sperm-binding protein 3" - - - gi|878283635|ref|NP_001297260.1|/1.08166e-130/membrane-spanning 4-domains subfamily A member 4A [Mus musculus] 12455 2175 2.33 2.993333333 0.361422989 Up 0.34909173 Ccnt1 cyclin T1 K15188|1|0.0|1295|mmu:12455|cyclin T GO:0008023//transcription elongation factor complex GO:0003723//RNA binding;GO:0019900//kinase binding;GO:0000975//regulatory region DNA binding "GO:0051726//regulation of cell cycle;GO:0006464//cellular protein modification process;GO:0006351//transcription, DNA-templated" gi|4324963|gb|AAD17205.1|/0/cyclin T [Mus musculus] 72114 2051.6 15.57 17.59 0.175986538 Up 0.349007108 Zbed3 "zinc finger, BED type containing 3" - GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0005488//binding GO:0030177//positive regulation of Wnt signaling pathway;GO:0031647//regulation of protein stability;GO:0030177//positive regulation of Wnt signaling pathway;GO:0031647//regulation of protein stability gi|21312432|ref|NP_082382.1|/7.85946e-88/zinc finger BED domain-containing protein 3 [Mus musculus] 11785 2411.43 54.76 60.67666667 0.148019385 Up 0.34889428 Apbb1 "amyloid beta (A4) precursor protein-binding, family B, member 1" K04529|1|0.0|910|mmu:11785|amyloid beta A4 precursor protein-binding family B member 1 GO:0032991//macromolecular complex;GO:0031252//cell leading edge;GO:0016604//nuclear body;GO:0030425//dendrite;GO:0044444//cytoplasmic part;GO:0097060//synaptic membrane;GO:0032991//macromolecular complex;GO:0031252//cell leading edge;GO:0016604//nuclear body;GO:0030425//dendrite;GO:0044444//cytoplasmic part;GO:0097060//synaptic membrane;GO:0032991//macromolecular complex;GO:0031252//cell leading edge;GO:0016604//nuclear body;GO:0030425//dendrite;GO:0044444//cytoplasmic part;GO:0097060//synaptic membrane;GO:0032991//macromolecular complex;GO:0031252//cell leading edge;GO:0016604//nuclear body;GO:0030425//dendrite;GO:0044444//cytoplasmic part;GO:0097060//synaptic membrane GO:0042277//peptide binding;GO:0019899//enzyme binding;GO:0042277//peptide binding;GO:0019899//enzyme binding;GO:0042277//peptide binding;GO:0019899//enzyme binding;GO:0042277//peptide binding;GO:0019899//enzyme binding GO:0006915//apoptotic process;GO:0006281//DNA repair;GO:0043062//extracellular structure organization;GO:0000084//mitotic S phase;GO:0016049//cell growth;GO:0016477//cell migration;GO:0006935//chemotaxis;GO:0030182//neuron differentiation;GO:0010038//response to metal ion;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007632//visual behavior;GO:0010558;GO:0031647//regulation of protein stability;GO:0009306//protein secretion;GO:0006915//apoptotic process;GO:0006281//DNA repair;GO:0043062//extracellular structure organization;GO:0000084//mitotic S phase;GO:0016049//cell growth;GO:0016477//cell migration;GO:0006935//chemotaxis;GO:0030182//neuron differentiation;GO:0010038//response to metal ion;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007632//visual behavior;GO:0010558;GO:0031647//regulation of protein stability;GO:0009306//protein secretion;GO:0006915//apoptotic process;GO:0006281//DNA repair;GO:0043062//extracellular structure organization;GO:0000084//mitotic S phase;GO:0016049//cell growth;GO:0016477//cell migration;GO:0006935//chemotaxis;GO:0030182//neuron differentiation;GO:0010038//response to metal ion;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007632//visual behavior;GO:0010558;GO:0031647//regulation of protein stability;GO:0009306//protein secretion;GO:0006915//apoptotic process;GO:0006281//DNA repair;GO:0043062//extracellular structure organization;GO:0000084//mitotic S phase;GO:0016049//cell growth;GO:0016477//cell migration;GO:0006935//chemotaxis;GO:0030182//neuron differentiation;GO:0010038//response to metal ion;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007632//visual behavior;GO:0010558;GO:0031647//regulation of protein stability;GO:0009306//protein secretion gi|795247514|ref|XP_011809697.1|/0/PREDICTED: amyloid beta A4 precursor protein-binding family B member 1 isoform X3 [Colobus angolensis palliatus] 27373 2788.02 28.82666667 32.28666667 0.16353448 Up 0.348762646 Csnk1e "casein kinase 1, epsilon" "K08960|1|0.0|704|umr:103676389|casein kinase 1, epsilon [EC:2.7.11.1]" GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004672//protein kinase activity GO:0030177//positive regulation of Wnt signaling pathway;GO:0006464//cellular protein modification process;GO:0007623//circadian rhythm;GO:0006796//phosphate-containing compound metabolic process;GO:0031331;GO:0008104//protein localization gi|568992597|ref|XP_006521106.1|/0/PREDICTED: casein kinase I isoform epsilon isoform X2 [Mus musculus] 76894 1891 4.863333333 4.013333333 -0.277144491 Down 0.348715634 Mettl15 methyltransferase like 15 K16667|1|1e-79|300|cqu:CpipJ_CPIJ014098|receptor-type tyrosine-protein phosphatase gamma [EC:3.1.3.48] - GO:0016741 GO:0008152//metabolic process gi|27229243|ref|NP_084066.2|/0/probable methyltransferase-like protein 15 [Mus musculus] 15568 6030 6.35 7.47 0.234351651 Up 0.348678025 Elavl1 "ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)" K13088|1|0.0|665|cjc:100896727|ELAV-like protein 1 GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0003730//mRNA 3'-UTR binding;GO:0019900//kinase binding;GO:0036094//small molecule binding GO:0006412//translation;GO:0016070//RNA metabolic process;GO:0048255//mRNA stabilization;GO:0032502//developmental process "gi|119589356|gb|EAW68950.1|/0/ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R), isoform CRA_b [Homo sapiens]" 12845 2447 0.5 0.9 0.847996907 Up 0.34862161 Comp cartilage oligomeric matrix protein K04659|1|0.0|1390|mmu:12845|thrombospondin 2/3/4/5 GO:0031012//extracellular matrix;GO:0044421 GO:0043168//anion binding;GO:0046872//metal ion binding;GO:0005496//steroid binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0005198//structural molecule activity GO:0043062//extracellular structure organization;GO:0022610;GO:0006915//apoptotic process;GO:0048736;GO:0003416//endochondral bone growth gi|162287140|ref|NP_057894.2|/0/cartilage oligomeric matrix protein precursor [Mus musculus] 22145 2099.78 568.6833333 515.2833333 -0.142259593 Down 0.348602806 Tuba4a "tubulin, alpha 4A" K07374|1|0.0|878|pale:102878622|tubulin alpha - - - - 94219 3301.8 2.103333333 2.73 0.376223447 Up 0.348602806 Cnnm2 cyclin M2 K16302|1|0.0|1481|mmu:94219|metal transporter CNNM GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459 - GO:0055065//metal ion homeostasis;GO:0070838//divalent metal ion transport;GO:0055065//metal ion homeostasis;GO:0070838//divalent metal ion transport "gi|148710072|gb|EDL42018.1|/0/cyclin M2, isoform CRA_a, partial [Mus musculus]" 19653 2274.51 4.636666667 5.556666667 0.261131684 Up 0.348584001 Rbm4 RNA binding motif protein 4 K13187|1|0.0|668|mmu:102902673|RNA-binding protein 4 - - - - 66445 1194 518.12 570.2333333 0.138266101 Up 0.348546391 Cyc1 cytochrome c-1 K00413|1|2e-138|494|mmu:66445|ubiquinol-cytochrome c reductase cytochrome c1 subunit GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044425 GO:0046872//metal ion binding - "gi|13385006|ref|NP_079843.1|/2.07479e-137/cytochrome c1, heme protein, mitochondrial [Mus musculus]" 56258 2449.15 19.09666667 21.55 0.174367032 Up 0.348536989 Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 K12898|1|0.0|768|cge:100773216|heterogeneous nuclear ribonucleoprotein F/H GO:0005856//cytoskeleton;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen GO:0036094//small molecule binding;GO:0003676//nucleic acid binding GO:0000377 "gi|148688440|gb|EDL20387.1|/0/heterogeneous nuclear ribonucleoprotein H2, isoform CRA_b, partial [Mus musculus]" 66734 1063 503.9866667 555.44 0.14024551 Up 0.348527587 Map1lc3a microtubule-associated protein 1 light chain 3 alpha K10435|1|2e-51|204|ptg:102964658|microtubule-associated protein 1 light chain GO:0015630//microtubule cytoskeleton;GO:0005768//endosome;GO:0005774//vacuolar membrane;GO:0031982//vesicle;GO:0015630//microtubule cytoskeleton;GO:0005768//endosome;GO:0005774//vacuolar membrane;GO:0031982//vesicle GO:0005543//phospholipid binding;GO:0015631//tubulin binding;GO:0005543//phospholipid binding;GO:0015631//tubulin binding GO:0007033//vacuole organization;GO:0006914//autophagy;GO:0007033//vacuole organization;GO:0006914//autophagy "gi|148674169|gb|EDL06116.1|/1.56651e-76/microtubule-associated protein 1 light chain 3 alpha, partial [Mus musculus]" 229699 1866 0.433333333 0.136666667 -1.664815808 Down 0.348414758 Slc16a4 "solute carrier family 16 (monocarboxylic acid transporters), member 4" "K08181|1|0.0|863|rno:295356|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 4" GO:0016021//integral component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0046943//carboxylic acid transmembrane transporter activity GO:0044763;GO:0046942//carboxylic acid transport gi|894216121|ref|NP_001297634.1|/0/monocarboxylate transporter 5 isoform 2 [Mus musculus] 210925 2695 8.306666667 9.623333333 0.212267039 Up 0.348339539 Ints9 integrator complex subunit 9 K13146|1|0.0|1312|rno:290322|integrator complex subunit 9 "GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0016591//DNA-directed RNA polymerase II, holoenzyme" GO:0005488//binding;GO:0005488//binding GO:0016073//snRNA metabolic process;GO:0016073//snRNA metabolic process "gi|148704090|gb|EDL36037.1|/0/DNA segment, Chr 14, ERATO Doi 231, expressed, isoform CRA_b, partial [Mus musculus]" 100504425 1269 0.273333333 0.616666667 1.173829456 Up 0.348320734 Gm20219 "predicted gene, 20219" - - - - - 170718 1520 477.7633333 432.9266667 -0.142173468 Down 0.348236113 Idh3b isocitrate dehydrogenase 3 (NAD+) beta K00030|1|0.0|707|mmu:170718|isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] GO:0030062//mitochondrial tricarboxylic acid cycle enzyme complex GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding GO:0043648//dicarboxylic acid metabolic process;GO:0072350//tricarboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0019674//NAD metabolic process "gi|18700024|ref|NP_570954.1|/0/isocitrate dehydrogenase [NAD] subunit beta, mitochondrial [Mus musculus]" 22612 4146 1.95 1.41 -0.467778961 Down 0.34822671 Yes1 "YES proto-oncogene 1, Src family tyrosine kinase" K05705|1|0.0|1089|mmu:22612|tyrosine-protein kinase Yes [EC:2.7.10.2] - - - - 17001 680 2.973333333 3.706666667 0.318041173 Up 0.348142089 Ltc4s leukotriene C4 synthase K00807|1|1e-40|167|mmu:17001|leukotriene-C4 synthase [EC:4.4.1.20] - - - - 80888 1825 421.4366667 463.5166667 0.137305375 Up 0.348104479 Hspb8 heat shock protein 8 K08879|1|2e-103|379|mmu:80888|heat shock protein beta-8 GO:0043231//intracellular membrane-bounded organelle GO:0016301//kinase activity;GO:0005515//protein binding GO:0050896//response to stimulus gi|13507646|ref|NP_109629.1|/1.74959e-102/heat shock protein beta-8 [Mus musculus] 218699 2807 19.89666667 22.32333333 0.166025714 Up 0.348085675 Pxk PX domain containing serine/threonine kinase K17543|1|0.0|1004|mmu:218699|PX domain-containing protein kinase-like protein GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0016301//kinase activity;GO:0032550;GO:0005543//phospholipid binding;GO:0008092//cytoskeletal protein binding GO:0043462//regulation of ATPase activity;GO:0007268//chemical synaptic transmission;GO:0006464//cellular protein modification process;GO:0006811//ion transport;GO:0006952//defense response gi|826265057|ref|XP_012520192.1|/0/PREDICTED: PX domain-containing protein kinase-like protein isoform X2 [Propithecus coquereli] 225742 2006 0.373333333 0.093333333 -2 Down 0.347963444 St8sia5 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5" "K03369|1|0.0|752|rno:364901|alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8E) [EC:2.4.99.-]" GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane GO:0008373//sialyltransferase activity;GO:0008373//sialyltransferase activity GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process "gi|257467533|ref|NP_038694.2|/0/alpha-2,8-sialyltransferase 8E isoform long [Mus musculus]" 100039957 2478 1.556666667 1.066666667 -0.545350645 Down 0.347954041 Gm2518 interferon induced transmembrane protein 2 pseudogene K03131|1|5e-159|564|mmu:225895|transcription initiation factor TFIID subunit 6 GO:0070461//SAGA-type complex GO:0008080//N-acetyltransferase activity;GO:0046983//protein dimerization activity "GO:0006355//regulation of transcription, DNA-templated;GO:0016573//histone acetylation" "gi|148701423|gb|EDL33370.1|/4.26714e-158/TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, isoform CRA_b, partial [Mus musculus]" 20655 661 365.2633333 403.7466667 0.144513412 Up 0.347944639 Sod1 "superoxide dismutase 1, soluble" "K04565|1|3e-86|319|mmu:20655|superoxide dismutase, Cu-Zn family [EC:1.15.1.1]" - - - gi|45597447|ref|NP_035564.1|/2.34719e-85/superoxide dismutase [Cu-Zn] [Mus musculus] 17311 5450 4.5 3.69 -0.286304185 Down 0.347907029 Kitl kit ligand K05461|1|2e-135|486|mmu:17311|KIT ligand GO:0031224//intrinsic component of membrane;GO:0043232;GO:0044421 GO:0005126//cytokine receptor binding GO:0001934//positive regulation of protein phosphorylation;GO:0007265//Ras protein signal transduction;GO:0001667//ameboidal-type cell migration;GO:0002573//myeloid leukocyte differentiation;GO:0008406//gonad development;GO:0070662//mast cell proliferation;GO:0030318//melanocyte differentiation;GO:0022610;GO:0043405//regulation of MAP kinase activity;GO:0033024;GO:0006260//DNA replication gi|7305267|ref|NP_038626.1|/2.09598e-134/kit ligand precursor [Mus musculus] 20523 1764 0.85 1.31 0.624032065 Up 0.347878822 Slc25a14 "solute carrier family 25 (mitochondrial carrier, brain), member 14" "K15106|1|0.0|636|mmu:20523|solute carrier family 25 (mitochondrial carrier), member 14/30" GO:0019866//organelle inner membrane;GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane - GO:0044765//single-organism transport;GO:0044765//single-organism transport;GO:0044765//single-organism transport;GO:0044765//single-organism transport gi|6755544|ref|NP_035528.1|/0/brain mitochondrial carrier protein 1 isoform 2 precursor [Mus musculus] 320714 4338 8.423333333 7.23 -0.220395611 Down 0.347850615 Trappc11 trafficking protein particle complex 11 K20308|1|0.0|2265|mmu:320714|trafficking protein particle complex subunit 11 GO:0043231//intracellular membrane-bounded organelle - GO:0006810//transport gi|62241019|ref|NP_796214.2|/0/trafficking protein particle complex subunit 11 [Mus musculus] 217371 1865 1.643333333 2.216666667 0.431766694 Up 0.347841213 Rab40b "Rab40B, member RAS oncogene family" K07928|1|3e-160|567|mmu:217371|Ras-related protein Rab-40 GO:0016020//membrane GO:0032550 GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization;GO:0032446//protein modification by small protein conjugation gi|253970492|ref|NP_631886.2|/2.73082e-159/ras-related protein Rab-40B [Mus musculus] 100502630 1090 1.65 2.22 0.428093652 Up 0.347841213 Gm15545 predicted gene 15545 - - - GO:0006915//apoptotic process "gi|148690833|gb|EDL22780.1|/8.94219e-20/BCL2-like 12 (proline rich), isoform CRA_a, partial [Mus musculus]" 235542 4905.97 58.17666667 52.56666667 -0.146292383 Down 0.347775396 Ppp2r3a "protein phosphatase 2, regulatory subunit B'', alpha" K11583|1|0.0|1010|fca:101083363|serine/threonine-protein phosphatase 2A regulatory subunit B'' - GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0009896;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0014807//regulation of somitogenesis;GO:0061061//muscle structure development;GO:0009896;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0014807//regulation of somitogenesis;GO:0061061//muscle structure development gi|254540097|ref|NP_742156.2|/0/serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform 2 [Mus musculus] 67574 4239 0.96 0.55 -0.803602787 Down 0.347756591 Alg13 asparagine-linked glycosylation 13 "K07432|1|9e-90|333|mmu:67574|beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141]" GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0008375//acetylglucosaminyltransferase activity GO:0030258//lipid modification;GO:0006487//protein N-linked glycosylation "gi|148682778|gb|EDL14725.1|/7.33188e-89/mCG8132, isoform CRA_c [Mus musculus]" 66624 2815 15.21666667 17.18333333 0.175357567 Up 0.347747189 Spcs2 signal peptidase complex subunit 2 homolog (S. cerevisiae) K12947|1|5e-107|391|ecb:100051902|signal peptidase complex subunit 2 [EC:3.4.-.-] GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane GO:0016787//hydrolase activity GO:0016485//protein processing gi|50979162|ref|NP_001003324.1|/4.40832e-106/signal peptidase complex subunit 2 [Canis lupus familiaris] 76178 3862 56.97333333 51.39666667 -0.14861202 Down 0.347728384 Coa5 cytochrome C oxidase assembly factor 5 K18178|1|2e-37|160|cge:100766959|cytochrome c oxidase assembly factor 5 GO:0043231//intracellular membrane-bounded organelle - - gi|625188306|ref|XP_003498334.2|/1.81427e-36/PREDICTED: cytochrome c oxidase assembly factor 5 [Cricetulus griseus] 546849 1227 0.45 0.146666667 -1.617383978 Down 0.347690774 Gm13178 predicted gene 13178 K14351|1|0.0|820|mmu:546849|arylacetamide deacetylase-like 3/4 [EC:3.1.1.-] GO:0031224//intrinsic component of membrane GO:0052689//carboxylic ester hydrolase activity - gi|148222101|ref|NP_001079005.1|/0/uncharacterized protein LOC546849 [Mus musculus] 12633 5650.15 5.82 6.853333333 0.235786706 Up 0.347662567 Cflar CASP8 and FADD-like apoptosis regulator K04724|1|0.0|912|mmu:12633|CASP8 and FADD-like apoptosis regulator GO:0031264//death-inducing signaling complex;GO:0044424;GO:0031264//death-inducing signaling complex;GO:0044424;GO:0031264//death-inducing signaling complex;GO:0044424;GO:0031264//death-inducing signaling complex;GO:0044424;GO:0031264//death-inducing signaling complex;GO:0044424 GO:0030234//enzyme regulator activity;GO:0030234//enzyme regulator activity;GO:0030234//enzyme regulator activity;GO:0030234//enzyme regulator activity;GO:0030234//enzyme regulator activity GO:0044093;GO:0097191//extrinsic apoptotic signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0044093;GO:0097191//extrinsic apoptotic signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0044093;GO:0097191//extrinsic apoptotic signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0044093;GO:0097191//extrinsic apoptotic signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0044093;GO:0097191//extrinsic apoptotic signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling "gi|148667680|gb|EDL00097.1|/7.08718e-124/CASP8 and FADD-like apoptosis regulator, isoform CRA_c, partial [Mus musculus]" 67710 868 27.91 31.23666667 0.162458384 Up 0.347540336 Polr2g polymerase (RNA) II (DNA directed) polypeptide G K03015|1|1e-89|329|cge:100754072|DNA-directed RNA polymerase II subunit RPB7 "GO:0016591//DNA-directed RNA polymerase II, holoenzyme" GO:0016301//kinase activity;GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0012501//programmed cell death;GO:0006397//mRNA processing;GO:0044764;GO:0006289//nucleotide-excision repair;GO:0000377;GO:0006464//cellular protein modification process gi|625226524|ref|XP_003514346.2|/1.1468e-88/PREDICTED: DNA-directed RNA polymerase II subunit RPB7 isoform X1 [Cricetulus griseus] 110078 3860 357.5166667 324.4533333 -0.139999511 Down 0.347502727 Pygb brain glycogen phosphorylase K00688|1|0.0|1651|mmu:110078|starch phosphorylase [EC:2.4.1.1] GO:0043005//neuron projection;GO:0044424 GO:0042802//identical protein binding;GO:0004645//phosphorylase activity;GO:0043168//anion binding GO:0005977//glycogen metabolic process "gi|24418919|ref|NP_722476.1|/0/glycogen phosphorylase, brain form [Mus musculus]" 75616 1864 5.58 4.673333333 -0.255813179 Down 0.347493324 Smim15 small integral membrane protein 15 - GO:0031224//intrinsic component of membrane - - "gi|148686509|gb|EDL18456.1|/4.98044e-36/mCG51409, isoform CRA_a, partial [Mus musculus]" 219249 3216.31 5.546666667 4.636666667 -0.258533014 Down 0.347493324 Tdrd3 tudor domain containing 3 K18404|1|0.0|1367|mmu:219249|tudor domain-containing protein 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0042393//histone binding;GO:0003712//transcription cofactor activity;GO:0042393//histone binding;GO:0003712//transcription cofactor activity - gi|359279950|ref|NP_001240684.1|/0/tudor domain-containing protein 3 isoform 2 [Mus musculus] 71519 2331 4.713333333 3.873333333 -0.283172051 Down 0.347446312 Cyp2u1 "cytochrome P450, family 2, subfamily u, polypeptide 1" "K07422|1|0.0|1044|mmu:71519|cytochrome P450, family 2, subfamily U, polypeptide 1" GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0044237//cellular metabolic process;GO:0044710 gi|189491662|ref|NP_082092.2|/0/cytochrome P450 2U1 [Mus musculus] 381308 1789 4.766666667 3.926666667 -0.279675608 Down 0.347446312 Mnda myeloid cell nuclear differentiation antigen K12971|1|3e-59|232|mmu:26388|interferon-activable protein 202;K12966|5|5e-38|161|ngi:103740252|absent in melanoma 2 GO:0016604//nuclear body;GO:0016604//nuclear body "GO:0005515//protein binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0043566//structure-specific DNA binding;GO:0005515//protein binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0043566//structure-specific DNA binding" GO:0031348//negative regulation of defense response;GO:0002253//activation of immune response;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0032611//interleukin-1 beta production;GO:0010951//negative regulation of endopeptidase activity;GO:0043583//ear development;GO:0072331//signal transduction by p53 class mediator;GO:0002573//myeloid leukocyte differentiation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0019079//viral genome replication;GO:0051100//negative regulation of binding;GO:0002252;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0010212//response to ionizing radiation;GO:0016049//cell growth;GO:0009267//cellular response to starvation;GO:0035456//response to interferon-beta;GO:0031348//negative regulation of defense response;GO:0002253//activation of immune response;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0032611//interleukin-1 beta production;GO:0010951//negative regulation of endopeptidase activity;GO:0043583//ear development;GO:0072331//signal transduction by p53 class mediator;GO:0002573//myeloid leukocyte differentiation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0019079//viral genome replication;GO:0051100//negative regulation of binding;GO:0002252;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0010212//response to ionizing radiation;GO:0016049//cell growth;GO:0009267//cellular response to starvation;GO:0035456//response to interferon-beta gi|84781795|ref|NP_001028622.1|/0/interferon-activable protein 205-B isoform 1 [Mus musculus] 78833 2412 0.453333333 0.84 0.889817082 Up 0.347418105 Gins3 GINS complex subunit 3 (Psf3 homolog) K10734|1|7e-121|437|mmu:78833|GINS complex subunit 3 GO:0043231//intracellular membrane-bounded organelle - GO:0006259//DNA metabolic process gi|21313504|ref|NP_084474.1|/5.83607e-120/DNA replication complex GINS protein PSF3 [Mus musculus] 68943 2367 314.13 346.1533333 0.140049511 Up 0.3473993 Pink1 PTEN induced putative kinase 1 K05688|1|0.0|1013|mmu:68943|PTEN induced putative kinase 1 [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|60360296|dbj|BAD90392.1|/0/mFLJ00387 protein [Mus musculus] 69810 685 0.103333333 0.396666667 1.940621453 Up 0.347248862 Clec4b1 "C-type lectin domain family 4, member b1" K17514|1|2e-100|366|mmu:69810|C-type lectin domain family 6 member A;K10057|2|2e-75|284|mmu:26888|C-type lectin domain family 4 member A GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding GO:0006952//defense response;GO:0050663//cytokine secretion;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006952//defense response;GO:0050663//cytokine secretion;GO:0007249//I-kappaB kinase/NF-kappaB signaling "gi|13386214|ref|NP_081494.1|/1.44732e-104/C-type lectin domain family 4, member b1 isoform 2 [Mus musculus]" 66523 1382 27.14333333 30.43 0.164896432 Up 0.347230058 2810004N23Rik RIKEN cDNA 2810004N23 gene - - - - gi|268836896|ref|NP_079891.2|/1.155e-121/uncharacterized protein C1orf131 homolog [Mus musculus] 93700 4739 2.573333333 1.96 -0.392784692 Down 0.347211253 Pcdhgb2 "protocadherin gamma subfamily B, 2" K16496|1|0.0|1682|mmu:93700|protocadherin gamma subfamily B GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|18087735|ref|NP_291053.1|/0/protocadherin gamma-B2 precursor [Mus musculus] 16573 6030 13.27666667 11.62666667 -0.19145544 Down 0.34720185 Kif5b kinesin family member 5B K10396|1|0.0|1823|mmu:16573|kinesin family member 5 GO:0005875//microtubule associated complex;GO:0042995//cell projection;GO:0044444//cytoplasmic part GO:0032550;GO:0003774//motor activity;GO:0015631//tubulin binding GO:0051648//vesicle localization;GO:0006813//potassium ion transport;GO:0006873//cellular ion homeostasis;GO:0051130//positive regulation of cellular component organization;GO:0006928//movement of cell or subcellular component;GO:0032988 gi|61657921|ref|NP_032474.2|/0/kinesin-1 heavy chain [Mus musculus] 12522 2134 0.806666667 1.26 0.643379187 Up 0.347154838 Cd83 CD83 antigen K06510|1|2e-107|392|mmu:12522|CD83 antigen - - - - 20471 2849 0.746666667 1.186666667 0.668378509 Up 0.347126631 Six1 sine oculis-related homeobox 1 K15614|1|1e-146|523|cge:100770482|homeobox protein SIX1 GO:0031981//nuclear lumen;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding GO:0048704//embryonic skeletal system morphogenesis;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0048534//hematopoietic or lymphoid organ development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0072079//nephron tubule formation;GO:0001656//metanephros development;GO:0021561//facial nerve development;GO:0050954//sensory perception of mechanical stimulus;GO:0001708//cell fate specification;GO:0014706//striated muscle tissue development;GO:0003266//regulation of secondary heart field cardioblast proliferation;GO:0033365//protein localization to organelle;GO:0051094//positive regulation of developmental process;GO:0042471//ear morphogenesis;GO:0014812//muscle cell migration;GO:0035270//endocrine system development;GO:0035904//aorta development;GO:0030182//neuron differentiation;GO:0051145//smooth muscle cell differentiation;GO:0048638//regulation of developmental growth;GO:0006366//transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0051093//negative regulation of developmental process "gi|148704568|gb|EDL36515.1|/7.24936e-165/sine oculis-related homeobox 1 homolog (Drosophila), partial [Mus musculus]" 11883 3491 6.976666667 8.153333333 0.224852092 Up 0.347107827 Arsa arylsulfatase A K01134|1|0.0|947|mmu:11883|arylsulfatase A [EC:3.1.6.8] GO:0031224//intrinsic component of membrane;GO:0009897//external side of plasma membrane;GO:0000323//lytic vacuole;GO:0044421 GO:0046872//metal ion binding;GO:0008484//sulfuric ester hydrolase activity GO:0044248;GO:0097305//response to alcohol;GO:0048545//response to steroid hormone;GO:0035036//sperm-egg recognition;GO:0009628//response to abiotic stimulus;GO:0031667//response to nutrient levels;GO:0007399//nervous system development gi|67972647|ref|NP_033843.2|/0/arylsulfatase A precursor [Mus musculus] 76933 464 48.57666667 54 0.152695912 Up 0.347089022 Ifi27l2a "interferon, alpha-inducible protein 27 like 2A" - - - - - 268739 5622 7.553333333 6.456666667 -0.226323907 Down 0.347079619 Arhgef40 Rho guanine nucleotide exchange factor (GEF) 40 K18655|1|2e-32|144|tsp:Tsp_05574|ATP-dependent RNA helicase DDX19/DBP5 [EC:3.6.4.13];K15048|2|8e-23|113|xma:102234732|kalirin [EC:2.7.11.1] GO:0044424;GO:0044424;GO:0044424 GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction gi|47847428|dbj|BAD21386.1|/0/mFLJ00128 protein [Mus musculus] 170731 4544.88 296.7766667 268.78 -0.142951877 Down 0.346938584 Mfn2 mitofusin 2 K06030|1|0.0|1438|mmu:170731|mitofusin [EC:3.6.5.-] GO:0005741//mitochondrial outer membrane;GO:0031224//intrinsic component of membrane;GO:0005856//cytoskeleton;GO:0005741//mitochondrial outer membrane;GO:0031224//intrinsic component of membrane;GO:0005856//cytoskeleton;GO:0005741//mitochondrial outer membrane;GO:0031224//intrinsic component of membrane;GO:0005856//cytoskeleton;GO:0005741//mitochondrial outer membrane;GO:0031224//intrinsic component of membrane;GO:0005856//cytoskeleton;GO:0005741//mitochondrial outer membrane;GO:0031224//intrinsic component of membrane;GO:0005856//cytoskeleton GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0044389//ubiquitin-like protein ligase binding GO:0007265//Ras protein signal transduction;GO:0051640//organelle localization;GO:0043010//camera-type eye development;GO:0006605//protein targeting;GO:0001824//blastocyst development;GO:0008285//negative regulation of cell proliferation;GO:0022402//cell cycle process;GO:0009154//purine ribonucleotide catabolic process;GO:0007005//mitochondrion organization;GO:0007265//Ras protein signal transduction;GO:0051640//organelle localization;GO:0043010//camera-type eye development;GO:0006605//protein targeting;GO:0001824//blastocyst development;GO:0008285//negative regulation of cell proliferation;GO:0022402//cell cycle process;GO:0009154//purine ribonucleotide catabolic process;GO:0007005//mitochondrion organization;GO:0007265//Ras protein signal transduction;GO:0051640//organelle localization;GO:0043010//camera-type eye development;GO:0006605//protein targeting;GO:0001824//blastocyst development;GO:0008285//negative regulation of cell proliferation;GO:0022402//cell cycle process;GO:0009154//purine ribonucleotide catabolic process;GO:0007005//mitochondrion organization;GO:0007265//Ras protein signal transduction;GO:0051640//organelle localization;GO:0043010//camera-type eye development;GO:0006605//protein targeting;GO:0001824//blastocyst development;GO:0008285//negative regulation of cell proliferation;GO:0022402//cell cycle process;GO:0009154//purine ribonucleotide catabolic process;GO:0007005//mitochondrion organization;GO:0007265//Ras protein signal transduction;GO:0051640//organelle localization;GO:0043010//camera-type eye development;GO:0006605//protein targeting;GO:0001824//blastocyst development;GO:0008285//negative regulation of cell proliferation;GO:0022402//cell cycle process;GO:0009154//purine ribonucleotide catabolic process;GO:0007005//mitochondrion organization "gi|148682839|gb|EDL14786.1|/0/mitofusin 2, isoform CRA_b, partial [Mus musculus]" 67621 1856.37 4.253333333 5.126666667 0.269427174 Up 0.346900974 Bend5 BEN domain containing 5 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - "gi|148698742|gb|EDL30689.1|/0/RIKEN cDNA 2310026E23, isoform CRA_c, partial [Mus musculus]" 50755 3539 20.96666667 18.59333333 -0.173312083 Down 0.346900974 Fbxo18 F-box protein 18 "K10300|1|0.0|2119|mmu:50755|F-box protein, helicase, 18 [EC:3.6.4.12]" GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003678//DNA helicase activity;GO:0032550 - gi|21703350|ref|NP_056607.1|/0/F-box DNA helicase 1 [Mus musculus] 18618 979.25 1.336666667 0.873333333 -0.614035425 Down 0.346863365 Pemt phosphatidylethanolamine N-methyltransferase K00551|1|5e-103|376|mmu:18618|phosphatidylethanolamine N-methyltransferase [EC:2.1.1.17] GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0005903//brush border;GO:0005740//mitochondrial envelope;GO:0005886//plasma membrane;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0005903//brush border;GO:0005740//mitochondrial envelope;GO:0005886//plasma membrane GO:0005543//phospholipid binding;GO:0008170//N-methyltransferase activity;GO:0005543//phospholipid binding;GO:0008170//N-methyltransferase activity GO:0008283//cell proliferation;GO:0031328//positive regulation of cellular biosynthetic process;GO:0046165;GO:0006790//sulfur compound metabolic process;GO:0001101//response to acid chemical;GO:0097305//response to alcohol;GO:0006644//phospholipid metabolic process;GO:0007584//response to nutrient;GO:0008283//cell proliferation;GO:0031328//positive regulation of cellular biosynthetic process;GO:0046165;GO:0006790//sulfur compound metabolic process;GO:0001101//response to acid chemical;GO:0097305//response to alcohol;GO:0006644//phospholipid metabolic process;GO:0007584//response to nutrient gi|585866350|ref|NP_001276940.1|/5.26347e-105/phosphatidylethanolamine N-methyltransferase isoform a [Mus musculus] 100504421 854 9.73 11.18 0.200408478 Up 0.346788145 2900076A07Rik RIKEN cDNA 2900076A07 gene - - - - - 20595 1248.64 11.38666667 9.933333333 -0.196995644 Down 0.346788145 Smn1 survival motor neuron 1 K13129|1|9e-110|399|mmu:20595|survival motor neuron protein GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0044444//cytoplasmic part GO:0019838//growth factor binding;GO:0019838//growth factor binding "GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0031109//microtubule polymerization or depolymerization;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0031109//microtubule polymerization or depolymerization;GO:0000398//mRNA splicing, via spliceosome" gi|6755580|ref|NP_035550.1|/7.28502e-109/survival motor neuron protein isoform 1 [Mus musculus] 232791 2923 18.45 20.81 0.173656149 Up 0.346759938 Cnot3 "CCR4-NOT transcription complex, subunit 3" K12580|1|0.0|1070|mmu:232791|CCR4-NOT transcription complex subunit 3 GO:0043234//protein complex;GO:0044424 GO:0005488//binding "GO:0051239;GO:0006351//transcription, DNA-templated" gi|22122717|ref|NP_666288.1|/0/CCR4-NOT transcription complex subunit 3 [Mus musculus] 100683 12476 3.646666667 2.93 -0.315677668 Down 0.346524879 Trrap transformation/transcription domain-associated protein K08874|1|0.0|7158|mmu:100683|transformation/transcription domain-associated protein - - - gi|124486949|ref|NP_001074831.1|/0/transformation/transcription domain-associated protein [Mus musculus] 93712 4534 1.023333333 1.506666667 0.558084117 Up 0.346477867 Pcdhga4 "protocadherin gamma subfamily A, 4" K16495|1|0.0|1772|mmu:93712|protocadherin gamma subfamily A;K16497|5|0.0|1521|mcc:702071|protocadherin gamma subfamily C GO:0031224//intrinsic component of membrane - GO:0016337//single organismal cell-cell adhesion gi|148747499|ref|NP_291065.3|/0/protocadherin gamma-A4 precursor [Mus musculus] 107371 2737 13.15333333 11.52 -0.191287739 Down 0.34644966 Exoc6 exocyst complex component 6 K19985|1|0.0|1544|mmu:107371|exocyst complex component 6 GO:0043234//protein complex - GO:0006887//exocytosis gi|62526126|ref|NP_780562.2|/0/exocyst complex component 6 [Mus musculus] 78912 3053.41 11.54 13.16666667 0.190246929 Up 0.34644966 Sp2 Sp2 transcription factor K09192|1|0.0|1006|mmu:78912|transcription factor Sp2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0019899//enzyme binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0019899//enzyme binding "GO:0048731//system development;GO:0040007//growth;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0009790//embryo development;GO:0048731//system development;GO:0040007//growth;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0009790//embryo development" gi|125625320|ref|NP_001074433.1|/0/transcription factor Sp2 isoform 2 [Mus musculus] 320456 2152 1.823333333 2.416666667 0.406440162 Up 0.346402648 B330016D10Rik RIKEN cDNA B330016D10 gene - - - - gi|26348823|dbj|BAC38051.1|/1.7306e-43/unnamed protein product [Mus musculus] 14187 1304 2.366666667 1.78 -0.410979283 Down 0.346402648 Akr1b8 "aldo-keto reductase family 1, member B8" K00011|1|3e-173|610|mmu:14187|aldehyde reductase [EC:1.1.1.21] GO:0044424 GO:0008106//alcohol dehydrogenase (NADP+) activity GO:0016107;GO:0030647 gi|6679791|ref|NP_032038.1|/2.26297e-172/aldose reductase-related protein 2 [Mus musculus] 23960 2069 0.63 1.053333333 0.741538324 Up 0.346383843 Oas1g 2'-5' oligoadenylate synthetase 1G K14216|1|0.0|402|mmu:23960|2'-5'-oligoadenylate synthetase [EC:2.7.7.84] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0032550;GO:0070566//adenylyltransferase activity;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0032550;GO:0070566//adenylyltransferase activity;GO:0003723//RNA binding GO:0006461//protein complex assembly;GO:0051707//response to other organism;GO:0019079//viral genome replication;GO:0032069;GO:0002252;GO:0035455//response to interferon-alpha;GO:0006163//purine nucleotide metabolic process;GO:0006952//defense response;GO:0006461//protein complex assembly;GO:0051707//response to other organism;GO:0019079//viral genome replication;GO:0032069;GO:0002252;GO:0035455//response to interferon-alpha;GO:0006163//purine nucleotide metabolic process;GO:0006952//defense response gi|31560524|ref|NP_035982.2|/0/2'-5' oligoadenylate synthetase 1G [Mus musculus] 56551 1282 237.84 261.7933333 0.138436991 Up 0.346383843 Txn2 thioredoxin 2 K03671|1|7e-91|336|mmu:56551|thioredoxin 1 GO:0043005//neuron projection;GO:0031981//nuclear lumen;GO:0044297//cell body "GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0005515//protein binding;GO:0015036//disulfide oxidoreductase activity" GO:0009746;GO:0009719;GO:0031667//response to nutrient levels;GO:0009611//response to wounding;GO:0006091//generation of precursor metabolites and energy;GO:0019725//cellular homeostasis;GO:0018904;GO:0051234//establishment of localization "gi|148697704|gb|EDL29651.1|/6.56028e-100/thioredoxin 2, isoform CRA_a, partial [Mus musculus]" 107047 1059 18.41666667 20.76 0.17279448 Up 0.346365038 Psmg2 "proteasome (prosome, macropain) assembly chaperone 2" K11876|1|2e-150|534|mmu:107047|proteasome assembly chaperone 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005488//binding GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0006915//apoptotic process;GO:0043623//cellular protein complex assembly gi|19527372|ref|NP_598899.1|/1.49858e-149/proteasome assembly chaperone 2 [Mus musculus] 67247 1883 19.17333333 21.51 0.16590635 Up 0.346365038 2-Mar mitochondrial amidoxime reducing component 2 K15631|1|2e-28|130|oaa:100075210|molybdenum cofactor sulfurtransferase [EC:2.8.1.9] GO:0019866//organelle inner membrane;GO:0042579//microbody;GO:0031966//mitochondrial membrane GO:0016661;GO:0046914//transition metal ion binding;GO:0043168//anion binding;GO:0050662//coenzyme binding GO:0043436 gi|19526848|ref|NP_598445.1|/2.03668e-178/mitochondrial amidoxime reducing component 2 precursor [Mus musculus] 217356 2763.24 3.35 4.123333333 0.299649999 Up 0.346355636 Tmc8 transmembrane channel-like gene family 8 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|304434590|ref|NP_001182017.1|/0/transmembrane channel-like protein 8 isoform A [Mus musculus] 100503636 1066 1.65 1.153333333 -0.516656487 Down 0.346327429 1700123M08Rik RIKEN cDNA 1700123M08 gene - - - - "gi|148673685|gb|EDL05632.1|/4.80269e-95/mCG123729, isoform CRA_a, partial [Mus musculus]" 56079 4831 0.793333333 0.416666667 -0.929033479 Down 0.346318026 Astn2 astrotactin 2 K14480|1|3e-36|157|oas:105606035|apolipoprotein L - - - "gi|148699133|gb|EDL31080.1|/0/astrotactin 2, isoform CRA_b, partial [Mus musculus]" 234683 3060 0.42 0.8 0.929610672 Up 0.346318026 Elmo3 engulfment and cell motility 3 K19241|1|0.0|1364|mmu:234683|engulfment and cell motility protein 3 GO:0043232 GO:0008289//lipid binding;GO:0019904//protein domain specific binding GO:0012501//programmed cell death;GO:0006897//endocytosis gi|255683297|ref|NP_766348.3|/0/engulfment and cell motility protein 3 [Mus musculus] 20377 4389 4.643333333 5.543333333 0.255592911 Up 0.34625221 Sfrp1 secreted frizzled-related protein 1 K02166|1|8e-155|551|mmu:20377|secreted frizzled-related protein 1 - - - gi|19353578|gb|AAH24495.1|/7.16934e-154/Secreted frizzled-related protein 1 [Mus musculus] 66681 2179 3.863333333 4.69 0.279741762 Up 0.3462146 Pgm1 phosphoglucomutase 1 K15779|1|0.0|1243|mmu:66681|phosphoglucomutase / phosphopentomutase [EC:5.4.2.2 5.4.2.7] - - - "gi|21410124|gb|AAH30869.1|/0/Pgm1 protein, partial [Mus musculus]" 382117 3053 16.7 14.78333333 -0.175876499 Down 0.346158186 Tcaim "T cell activation inhibitor, mitochondrial" - GO:0043231//intracellular membrane-bounded organelle - - "gi|237512974|ref|NP_001013423.2|/0/T-cell activation inhibitor, mitochondrial [Mus musculus] " 80985 5612 9.583333333 8.303333333 -0.206836934 Down 0.346120576 Trim44 tripartite motif-containing 44 K12020|1|2e-97|360|mmu:80985|tripartite motif-containing protein 44 GO:0044464 GO:0046914//transition metal ion binding - "gi|148695720|gb|EDL27667.1|/1.79108e-96/tripartite motif-containing 44, isoform CRA_a, partial [Mus musculus]" 68939 1860 9.273333333 7.993333333 -0.214290761 Down 0.346120576 Rasl11b "RAS-like, family 11, member B" K07853|1|2e-134|482|mmu:68939|Ras-like protein family member 11B - GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process gi|110625708|ref|NP_081154.1|/1.50572e-133/ras-like protein family member 11B [Mus musculus] 19885 2576.28 30.65 27.46 -0.158555448 Down 0.346082967 Rorc RAR-related orphan receptor gamma K08534|1|0.0|944|mmu:19885|RAR-related orphan receptor gamma GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding" "GO:0006366//transcription from RNA polymerase II promoter;GO:0042093//T-helper cell differentiation;GO:0009755//hormone-mediated signaling pathway;GO:0006464//cellular protein modification process;GO:0006351//transcription, DNA-templated;GO:0042093//T-helper cell differentiation;GO:0009755//hormone-mediated signaling pathway;GO:0006464//cellular protein modification process;GO:0006351//transcription, DNA-templated;GO:0042093//T-helper cell differentiation;GO:0009755//hormone-mediated signaling pathway;GO:0006464//cellular protein modification process" gi|74202317|dbj|BAE23510.1|/1.81603e-167/unnamed protein product [Mus musculus] 11911 1627.03 47.98 53.12333333 0.146912517 Up 0.346064162 Atf4 activating transcription factor 4 K04374|1|9e-146|519|mmu:11911|cyclic AMP-dependent transcription factor ATF-4 GO:0043231//intracellular membrane-bounded organelle;GO:0032589//neuron projection membrane;GO:0043234//protein complex;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0032589//neuron projection membrane;GO:0043234//protein complex;GO:0005856//cytoskeleton GO:0005515//protein binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003677//DNA binding GO:0007186//G-protein coupled receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0034976//response to endoplasmic reticulum stress;GO:0043065//positive regulation of apoptotic process;GO:0006006//glucose metabolic process;GO:0006813//potassium ion transport;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0034976//response to endoplasmic reticulum stress;GO:0043065//positive regulation of apoptotic process;GO:0006006//glucose metabolic process;GO:0006813//potassium ion transport gi|74199225|dbj|BAE33149.1|/7.82528e-145/unnamed protein product [Mus musculus] 66039 2149 0.69 0.336666667 -1.035275475 Down 0.346026552 Tmem254a transmembrane protein 254a - - - - gi|292781931|ref|NP_080955.1|/7.44444e-63/transmembrane protein 254 isoform 1 [Mus musculus] 64051 3920 1.266666667 0.82 -0.627341103 Down 0.345988943 Sv2a synaptic vesicle glycoprotein 2 a "K06258|1|0.0|1264|rno:117559|MFS transporter, VNT family, synaptic vesicle glycoprotein 2" GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0008021//synaptic vesicle;GO:0042995//cell projection GO:0005488//binding;GO:0005215//transporter activity GO:0007267//cell-cell signaling;GO:0006875//cellular metal ion homeostasis;GO:0044765//single-organism transport gi|148747227|ref|NP_476558.2|/0/synaptic vesicle glycoprotein 2A [Rattus norvegicus] 18018 4485.46 10.93333333 9.506666667 -0.201721833 Down 0.345913724 Nfatc1 "nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1" "K04446|1|0.0|1531|rno:100361818|nuclear factor of activated T-cells, cytoplasmic 1" GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0051019//mitogen-activated protein kinase binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding;GO:0008134//transcription factor binding;GO:0051019//mitogen-activated protein kinase binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding;GO:0008134//transcription factor binding;GO:0051019//mitogen-activated protein kinase binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding;GO:0008134//transcription factor binding;GO:0051019//mitogen-activated protein kinase binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding;GO:0008134//transcription factor binding;GO:0051019//mitogen-activated protein kinase binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding;GO:0008134//transcription factor binding;GO:0051019//mitogen-activated protein kinase binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding;GO:0008134//transcription factor binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0002573//myeloid leukocyte differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0002573//myeloid leukocyte differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0002573//myeloid leukocyte differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0002573//myeloid leukocyte differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0002573//myeloid leukocyte differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0002573//myeloid leukocyte differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0007165//signal transduction;GO:0070838//divalent metal ion transport "gi|255759919|ref|NP_001157581.1|/0/nuclear factor of activated T-cells, cytoplasmic 1 isoform 3 [Mus musculus]" 12015 1033.39 14.75333333 16.66666667 0.175924644 Up 0.345904321 Bad BCL2-associated agonist of cell death K02158|1|2e-110|402|mmu:12015|Bcl-2-antagonist of cell death GO:0031966//mitochondrial membrane;GO:0031966//mitochondrial membrane GO:0016505//peptidase activator activity involved in apoptotic process;GO:0008289//lipid binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0046983//protein dimerization activity;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0008289//lipid binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0046983//protein dimerization activity GO:0032024//positive regulation of insulin secretion;GO:0010822//positive regulation of mitochondrion organization;GO:0010720//positive regulation of cell development;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0009612//response to mechanical stimulus;GO:0022607//cellular component assembly;GO:0051726//regulation of cell cycle;GO:0031960//response to corticosteroid;GO:0006508//proteolysis;GO:0046687//response to chromate;GO:0030217//T cell differentiation;GO:0001666//response to hypoxia;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0012502//induction of programmed cell death;GO:0033500//carbohydrate homeostasis;GO:0000302//response to reactive oxygen species;GO:0033131;GO:0001101//response to acid chemical;GO:0043627//response to estrogen;GO:0030183//B cell differentiation;GO:0007166//cell surface receptor signaling pathway;GO:0010038//response to metal ion;GO:0009150//purine ribonucleotide metabolic process;GO:0035556//intracellular signal transduction;GO:0006839//mitochondrial transport;GO:0009746;GO:0035094//response to nicotine;GO:0070542//response to fatty acid;GO:0045838//positive regulation of membrane potential;GO:0097305//response to alcohol;GO:0032024//positive regulation of insulin secretion;GO:0010822//positive regulation of mitochondrion organization;GO:0010720//positive regulation of cell development;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0009612//response to mechanical stimulus;GO:0022607//cellular component assembly;GO:0051726//regulation of cell cycle;GO:0031960//response to corticosteroid;GO:0006508//proteolysis;GO:0046687//response to chromate;GO:0030217//T cell differentiation;GO:0001666//response to hypoxia;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0012502//induction of programmed cell death;GO:0033500//carbohydrate homeostasis;GO:0000302//response to reactive oxygen species;GO:0033131;GO:0001101//response to acid chemical;GO:0043627//response to estrogen;GO:0030183//B cell differentiation;GO:0007166//cell surface receptor signaling pathway;GO:0010038//response to metal ion;GO:0009150//purine ribonucleotide metabolic process;GO:0035556//intracellular signal transduction;GO:0006839//mitochondrial transport;GO:0009746;GO:0035094//response to nicotine;GO:0070542//response to fatty acid;GO:0045838//positive regulation of membrane potential;GO:0097305//response to alcohol gi|74139308|dbj|BAE40801.1|/4.48216e-91/unnamed protein product [Mus musculus] 19708 3341.99 27.59666667 30.76333333 0.156717816 Up 0.345810297 Dpf2 "D4, zinc and double PHD fingers family 2" K13196|1|0.0|760|pps:100978656|zinc finger protein ubi-d4 GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding "GO:0012502//induction of programmed cell death;GO:0007165//signal transduction;GO:0006351//transcription, DNA-templated" gi|675790473|ref|XP_003828671.2|/0/PREDICTED: zinc finger protein ubi-d4 isoform X2 [Pan paniscus] 13196 6155.15 8.043333333 6.886666667 -0.223987661 Down 0.345641055 Asap1 "ArfGAP with SH3 domain, ankyrin repeat and PH domain1" "K12488|1|0.0|1808|mmu:13196|Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein" GO:0044424;GO:0044424;GO:0044424 "GO:0046914//transition metal ion binding;GO:0030674//protein binding, bridging;GO:0019904//protein domain specific binding;GO:0008289//lipid binding;GO:0046914//transition metal ion binding;GO:0030674//protein binding, bridging;GO:0019904//protein domain specific binding;GO:0008289//lipid binding;GO:0046914//transition metal ion binding;GO:0030674//protein binding, bridging;GO:0019904//protein domain specific binding;GO:0008289//lipid binding" GO:0032012//regulation of ARF protein signal transduction;GO:0030031//cell projection assembly;GO:0048858//cell projection morphogenesis;GO:0032012//regulation of ARF protein signal transduction;GO:0030031//cell projection assembly;GO:0048858//cell projection morphogenesis;GO:0032012//regulation of ARF protein signal transduction;GO:0030031//cell projection assembly;GO:0048858//cell projection morphogenesis gi|74138897|dbj|BAE27250.1|/0/unnamed protein product [Mus musculus] 330064 3295.62 4.923333333 5.87 0.253725083 Up 0.345631652 Slc5a6 "solute carrier family 5 (sodium-dependent vitamin transporter), member 6" "K14386|1|0.0|1112|mmu:330064|solute carrier family 5 (sodium-dependent multivitamin transporter), member 6" GO:0031224//intrinsic component of membrane;GO:0005903//brush border;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0005903//brush border;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0005903//brush border;GO:0012505//endomembrane system GO:0015370//solute:sodium symporter activity;GO:0015370//solute:sodium symporter activity;GO:0015370//solute:sodium symporter activity GO:0003333//amino acid transmembrane transport;GO:0015718//monocarboxylic acid transport;GO:0030001//metal ion transport;GO:0003333//amino acid transmembrane transport;GO:0015718//monocarboxylic acid transport;GO:0030001//metal ion transport;GO:0003333//amino acid transmembrane transport;GO:0015718//monocarboxylic acid transport;GO:0030001//metal ion transport "gi|148705373|gb|EDL37320.1|/0/mCG23491, isoform CRA_a, partial [Mus musculus]" 29805 1262 8.153333333 9.42 0.208337062 Up 0.34558464 Znhit2 "zinc finger, HIT domain containing 2" - - - - "gi|18044459|gb|AAH19440.1|/7.944e-159/Zinc finger, HIT domain containing 2 [Mus musculus]" 50849 3121.28 189.92 209.95 0.144653948 Up 0.345537628 Rnf10 ring finger protein 10 K13346|1|1e-07|62.0|dpe:Dper_GL17108|peroxin-10 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0000975//regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0000975//regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0000975//regulatory region DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0031641//regulation of myelination;GO:0010624;GO:0006366//transcription from RNA polymerase II promoter;GO:0031641//regulation of myelination;GO:0010624;GO:0006366//transcription from RNA polymerase II promoter;GO:0031641//regulation of myelination;GO:0010624 gi|698980065|ref|NP_001289378.1|/0/RING finger protein 10 isoform 3 [Mus musculus] 209200 5181 6.103333333 7.18 0.234386459 Up 0.345462409 Dtx3l "deltex 3-like, E3 ubiquitin ligase" K06058|1|0.0|1474|mmu:209200|deltex [EC:2.3.2.27] - - - - 15163 2031 9.48 10.89666667 0.200927912 Up 0.345405995 Hcls1 hematopoietic cell specific Lyn substrate 1 K06106|1|0.0|824|mmu:15163|cortactin GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0019904//protein domain specific binding GO:0008064//regulation of actin polymerization or depolymerization;GO:0001934//positive regulation of protein phosphorylation;GO:0042307//positive regulation of protein import into nucleus;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0043066//negative regulation of apoptotic process;GO:0034097//response to cytokine;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0009719 "gi|148665533|gb|EDK97949.1|/0/hematopoietic cell specific Lyn substrate 1, partial [Mus musculus]" 13424 14398 29.13333333 26.01 -0.16360438 Down 0.345368385 Dync1h1 dynein cytoplasmic 1 heavy chain 1 "K10413|1|0.0|9088|mmu:13424|dynein heavy chain 1, cytosolic" GO:0005815//microtubule organizing center;GO:0031988//membrane-bounded vesicle;GO:0030286//dynein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0032550;GO:0003774//motor activity;GO:0016887//ATPase activity GO:0002478;GO:0044772//mitotic cell cycle phase transition;GO:0006928//movement of cell or subcellular component;GO:0051234//establishment of localization;GO:0022618//ribonucleoprotein complex assembly gi|134288917|ref|NP_084514.2|/0/cytoplasmic dynein 1 heavy chain 1 [Mus musculus] 434402 633 11.47 13.07333333 0.188761643 Up 0.345340178 Gm5617 predicted gene 5617 - - - - gi|256000799|ref|NP_001004191.2|/1.18012e-35/uncharacterized protein C11orf71 homolog [Mus musculus] 20737 3751 0.42 0.796666667 0.923586884 Up 0.345321374 Spn sialophorin K06477|1|7e-153|544|mmu:20737|sialophorin GO:0016021//integral component of membrane;GO:0032155;GO:0009986//cell surface;GO:0005578//proteinaceous extracellular matrix;GO:0031254//cell trailing edge;GO:0042995//cell projection;GO:0016021//integral component of membrane;GO:0032155;GO:0009986//cell surface;GO:0005578//proteinaceous extracellular matrix;GO:0031254//cell trailing edge;GO:0042995//cell projection;GO:0016021//integral component of membrane;GO:0032155;GO:0009986//cell surface;GO:0005578//proteinaceous extracellular matrix;GO:0031254//cell trailing edge;GO:0042995//cell projection GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0001806//type IV hypersensitivity;GO:0002274;GO:0002697;GO:0031294//lymphocyte costimulation;GO:0007165//signal transduction;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0070489//T cell aggregation;GO:0043383//negative T cell selection;GO:0042098//T cell proliferation;GO:0001806//type IV hypersensitivity;GO:0002274;GO:0002697;GO:0031294//lymphocyte costimulation;GO:0007165//signal transduction;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0070489//T cell aggregation;GO:0043383//negative T cell selection;GO:0042098//T cell proliferation;GO:0001806//type IV hypersensitivity;GO:0002274;GO:0002697;GO:0031294//lymphocyte costimulation;GO:0007165//signal transduction;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0070489//T cell aggregation;GO:0043383//negative T cell selection;GO:0042098//T cell proliferation gi|755522305|ref|XP_011240018.1|/5.64263e-152/PREDICTED: leukosialin isoform X2 [Mus musculus] 269623 2344 2.25 2.893333333 0.362807541 Up 0.345283764 Rbm48 RNA binding motif protein 48 K13338|1|3e-08|63.2|ssc:100626142|peroxin-1 GO:0031981//nuclear lumen GO:0003676//nucleic acid binding - gi|282396075|ref|NP_766579.3|/0/RNA-binding protein 48 [Mus musculus] 79554 2662 2.253333333 2.896666667 0.362332931 Up 0.345283764 Cptp ceramide-1-phosphate transfer protein K08051|1|4e-09|66.6|mze:101464548|pleckstrin homology domain containing family A member 8 GO:0044424 GO:0005319//lipid transporter activity;GO:0008289//lipid binding GO:0006869//lipid transport gi|31560025|ref|NP_077792.2|/7.2628e-119/ceramide-1-phosphate transfer protein [Mus musculus] 17991 602 178.9533333 197.71 0.143802426 Up 0.345274362 Ndufa2 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2" K03946|1|4e-43|176|mmu:17991|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2 GO:0005746//mitochondrial respiratory chain GO:0050136//NADH dehydrogenase (quinone) activity GO:0051234//establishment of localization;GO:0044710;GO:0006091//generation of precursor metabolites and energy gi|31981600|ref|NP_035015.2|/2.51996e-42/NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 [Mus musculus] 319155 375 0.01 0.203333333 4.345774837 Up 0.34518974 Hist1h4c "histone cluster 1, H4c" K11254|1|2e-41|169|ecb:100068166|histone H4;K11253|2|3e-40|165|oaa:100089390|histone H3 - - - gi|625285956|ref|XP_007634698.1|/1.57138e-40/PREDICTED: LOW QUALITY PROTEIN: histone H4 isoform X2 [Cricetulus griseus] 100859962 522 0.203333333 0.01 -4.345774837 Down 0.34518974 Gm21057 "predicted gene, 21057" - - - - "gi|148675091|gb|EDL07038.1|/1.18193e-32/mCG1028355, partial [Mus musculus]" 66511 2988.71 26.07333333 29.17333333 0.162075202 Up 0.345180338 Chtop chromatin target of PRMT1 - GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|18027816|gb|AAL55869.1|AF318362_1/2.91527e-20/unknown [Homo sapiens] 110596 6259 1.516666667 1.033333333 -0.55359833 Down 0.345161533 Arhgef28 Rho guanine nucleotide exchange factor (GEF) 28 K16529|1|0.0|1537|acs:100568036|A-kinase anchor protein 13 GO:0044424;GO:0016020//membrane GO:0043169//cation binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding GO:0007409//axonogenesis;GO:0045104//intermediate filament cytoskeleton organization;GO:0007266//Rho protein signal transduction gi|568984196|ref|XP_006517581.1|/0/PREDICTED: rho guanine nucleotide exchange factor 28 isoform X1 [Mus musculus] 15365 1510 1.19 1.69 0.506061673 Up 0.345161533 Hmga2-ps1 "high mobility group AT-hook 2, pseudogene 1" K09283|1|2e-11|73.2|ssc:100513206|high mobility group AT-hook protein 2 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin "GO:0044212//transcription regulatory region DNA binding;GO:0016835//carbon-oxygen lyase activity;GO:0019904//protein domain specific binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding" GO:0001704//formation of primary germ layer;GO:0006915//apoptotic process;GO:0006281//DNA repair;GO:0008284//positive regulation of cell proliferation;GO:0044093;GO:0031327;GO:2001141//regulation of RNA biosynthetic process;GO:2000242//negative regulation of reproductive process;GO:0030072//peptide hormone secretion;GO:0022402//cell cycle process;GO:0051726//regulation of cell cycle;GO:0030900//forebrain development;GO:0031507//heterochromatin assembly;GO:0023051//regulation of signaling;GO:0040007//growth;GO:0035270//endocrine system development;GO:0051101//regulation of DNA binding;GO:0010646//regulation of cell communication;GO:0002791//regulation of peptide secretion;GO:0060612//adipose tissue development;GO:0006366//transcription from RNA polymerase II promoter;GO:0050792//regulation of viral process;GO:0051239;GO:0051253;GO:0090398//cellular senescence;GO:0010558;GO:0019827//stem cell population maintenance;GO:0048584;GO:0060284//regulation of cell development;GO:0019058//viral life cycle gi|12851702|dbj|BAB29137.1|/3.33345e-16/unnamed protein product [Mus musculus] 319336 1266 0.983333333 0.576666667 -0.769942917 Down 0.345161533 C130036L24Rik RIKEN cDNA C130036L24 gene - - - - - 66141 648 177.2033333 195.58 0.142353106 Up 0.345152131 Ifitm3 interferon induced transmembrane protein 3 K06566|1|2e-58|227|mmu:66141|interferon induced transmembrane protein GO:0031224//intrinsic component of membrane;GO:0005770//late endosome - GO:0046718//viral entry into host cell;GO:0006952//defense response;GO:0051707//response to other organism;GO:0019221//cytokine-mediated signaling pathway;GO:0002252;GO:0008283//cell proliferation gi|21539593|ref|NP_079654.1|/1.17002e-57/interferon-induced transmembrane protein 3 [Mus musculus] 19324 2657 43.85666667 48.72666667 0.151915369 Up 0.345076912 Rab1a "RAB1A, member RAS oncogene family" K07874|1|3e-113|412|phi:102110208|Ras-related protein Rab-1A GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0031090//organelle membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0007265//Ras protein signal transduction;GO:0016482//cytosolic transport;GO:0015031//protein transport;GO:0009154//purine ribonucleotide catabolic process gi|676264806|gb|KFO21151.1|/6.35387e-115/Ras-related protein Rab-1A [Fukomys damarensis] 52686 2619 6.97 8.123333333 0.220913189 Up 0.344954681 Mettl2 methyltransferase like 2 K15264|1|6e-60|235|cbr:CBG20899|putative methyltransferase [EC:2.1.1.-];K00599|2|3e-52|209|aga:AgaP_AGAP009818|methyltransferase-like protein 6 [EC:2.1.1.-] - GO:0016741 GO:0008152//metabolic process gi|255683413|ref|NP_766155.3|/0/methyltransferase-like protein 2 [Mus musculus] 74577 3451 3.116666667 3.853333333 0.306103128 Up 0.344917071 Glb1l "galactosidase, beta 1-like" K12309|1|0.0|699|lcm:102353144|beta-galactosidase [EC:3.2.1.23] - GO:0015925//galactosidase activity GO:0044238//primary metabolic process gi|254675347|ref|NP_083286.1|/0/beta-galactosidase-1-like protein precursor [Mus musculus] 69920 707 27.08333333 30.16333333 0.155390557 Up 0.344907669 Polr2i polymerase (RNA) II (DNA directed) polypeptide I K03017|1|3e-73|276|mdo:100014201|DNA-directed RNA polymerase II subunit RPB9 "GO:0016591//DNA-directed RNA polymerase II, holoenzyme" GO:0046914//transition metal ion binding;GO:0016301//kinase activity;GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006397//mRNA processing;GO:0044764;GO:0006289//nucleotide-excision repair;GO:0000377;GO:0006464//cellular protein modification process gi|148692091|gb|EDL24038.1|/5.59086e-99/mCG22814 [Mus musculus] 72535 2302 9.143333333 7.886666667 -0.213304549 Down 0.344851254 Aldh1b1 "aldehyde dehydrogenase 1 family, member B1" K00128|1|0.0|993|mmu:72535|aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] GO:0044429;GO:0031981//nuclear lumen "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor" GO:0006067//ethanol metabolic process "gi|21312260|ref|NP_082546.1|/0/aldehyde dehydrogenase X, mitochondrial precursor [Mus musculus]" 72615 2483 3.223333333 3.98 0.304215042 Up 0.344813645 Anks3 ankyrin repeat and sterile alpha motif domain containing 3 K15503|1|1e-29|134|aqu:100635111|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B - - - - 240725 4620.75 4.076666667 3.313333333 -0.299106647 Down 0.344813645 Sulf1 sulfatase 1 K14607|1|0.0|1706|mmu:240725|extracellular sulfatase Sulf [EC:3.1.6.-] GO:0044431//Golgi apparatus part;GO:0044425;GO:0044421;GO:0044431//Golgi apparatus part;GO:0044425;GO:0044421;GO:0044431//Golgi apparatus part;GO:0044425;GO:0044421 GO:0008484//sulfuric ester hydrolase activity;GO:0046872//metal ion binding;GO:0008484//sulfuric ester hydrolase activity;GO:0046872//metal ion binding;GO:0008484//sulfuric ester hydrolase activity;GO:0046872//metal ion binding GO:0001525//angiogenesis;GO:0002062//chondrocyte differentiation;GO:0006029//proteoglycan metabolic process;GO:0051093//negative regulation of developmental process;GO:0016055//Wnt signaling pathway;GO:0012501//programmed cell death;GO:0030198//extracellular matrix organization;GO:0001935//endothelial cell proliferation;GO:0014831//gastro-intestinal system smooth muscle contraction;GO:0022610;GO:0001819//positive regulation of cytokine production;GO:0008284//positive regulation of cell proliferation;GO:0097205//renal filtration;GO:0021675//nerve development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0030509//BMP signaling pathway;GO:0016477//cell migration;GO:0001525//angiogenesis;GO:0002062//chondrocyte differentiation;GO:0006029//proteoglycan metabolic process;GO:0051093//negative regulation of developmental process;GO:0016055//Wnt signaling pathway;GO:0012501//programmed cell death;GO:0030198//extracellular matrix organization;GO:0001935//endothelial cell proliferation;GO:0014831//gastro-intestinal system smooth muscle contraction;GO:0022610;GO:0001819//positive regulation of cytokine production;GO:0008284//positive regulation of cell proliferation;GO:0097205//renal filtration;GO:0021675//nerve development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0030509//BMP signaling pathway;GO:0016477//cell migration;GO:0001525//angiogenesis;GO:0002062//chondrocyte differentiation;GO:0006029//proteoglycan metabolic process;GO:0051093//negative regulation of developmental process;GO:0016055//Wnt signaling pathway;GO:0012501//programmed cell death;GO:0030198//extracellular matrix organization;GO:0001935//endothelial cell proliferation;GO:0014831//gastro-intestinal system smooth muscle contraction;GO:0022610;GO:0001819//positive regulation of cytokine production;GO:0008284//positive regulation of cell proliferation;GO:0097205//renal filtration;GO:0021675//nerve development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0030509//BMP signaling pathway;GO:0016477//cell migration gi|26986617|ref|NP_758498.1|/0/extracellular sulfatase Sulf-1 precursor [Mus musculus] 353502 1243 163.71 180.9633333 0.144554959 Up 0.344785438 Hcfc1r1 host cell factor C1 regulator 1 (XPO1-dependent) - GO:0043231//intracellular membrane-bounded organelle - - gi|32451500|ref|NP_861542.1|/5.03679e-65/host cell factor C1 regulator 1 [Mus musculus] 76964 1763 0.71 1.136666667 0.678918309 Up 0.344738426 2610028H24Rik RIKEN cDNA 2610028H24 gene - - - - gi|158534073|ref|NP_084092.2|/4.55764e-92/uncharacterized protein C21orf58 homolog [Mus musculus] 56176 800.49 43.92666667 48.70666667 0.149022227 Up 0.344691414 Pigp "phosphatidylinositol glycan anchor biosynthesis, class P" "K03861|1|2e-54|214|hsa:51227|phosphatidylinositol glycan, class P" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0031090//organelle membrane GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity GO:0006506//GPI anchor biosynthetic process;GO:0006497//protein lipidation;GO:0006506//GPI anchor biosynthetic process;GO:0006497//protein lipidation;GO:0006506//GPI anchor biosynthetic process;GO:0006506//GPI anchor biosynthetic process gi|227498255|ref|NP_001153090.1|/6.64151e-88/phosphatidylinositol N-acetylglucosaminyltransferase subunit P isoform b [Mus musculus] 242474 6895 6.426666667 5.426666667 -0.244004352 Down 0.344691414 Tmem245 transmembrane protein 245 "K03847|1|3e-07|42.7|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - gi|126723478|ref|NP_780727.3|/0/transmembrane protein 245 [Mus musculus] 211480 2639 0.743333333 0.373333333 -0.993544978 Down 0.344653804 Kcnj14 "potassium inwardly-rectifying channel, subfamily J, member 14" K05007|1|0.0|791|mmu:211480|potassium inwardly-rectifying channel subfamily J member 14 GO:0043005//neuron projection;GO:0044297//cell body;GO:0005887//integral component of plasma membrane GO:0005249//voltage-gated potassium channel activity GO:0007267//cell-cell signaling;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|22122399|ref|NP_666075.1|/0/ATP-sensitive inward rectifier potassium channel 14 [Mus musculus] 415115 1156 25.71666667 28.77666667 0.162195832 Up 0.344644402 Neurl2 neuralized E3 ubiquitin protein ligase 2 K16782|1|2e-154|547|mmu:415115|neuralized-like protein 2 GO:0005924//cell-substrate adherens junction;GO:0000153//cytoplasmic ubiquitin ligase complex - GO:0030239//myofibril assembly;GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation "gi|148674480|gb|EDL06427.1|/3.24264e-156/mCG17526, partial [Mus musculus]" 52480 2204 0.87 0.483333333 -0.847996907 Down 0.344540976 Snhg14 small nucleolar RNA host gene 14 - - - - - 53859 4173 1.32 1.836666667 0.476551888 Up 0.344503366 Map3k14 mitogen-activated protein kinase kinase kinase 14 K04466|1|0.0|1715|mmu:53859|mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25] GO:0044424 GO:0032550;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0006464//cellular protein modification process;GO:0002376//immune system process;GO:0006796//phosphate-containing compound metabolic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|8393835|ref|NP_058592.1|/0/mitogen-activated protein kinase kinase kinase 14 [Mus musculus] 23880 4959.36 0.96 1.426666667 0.571541985 Up 0.34439994 Fyb FYN binding protein K17698|1|0.0|1209|mmu:23880|FYN binding protein - GO:0005515//protein binding;GO:0005515//protein binding GO:0002274;GO:0002274 gi|568990266|ref|XP_006520048.1|/0/PREDICTED: FYN-binding protein isoform X5 [Mus musculus] 26382 2631.03 0.973333333 1.446666667 0.571726674 Up 0.34439994 Fgd2 "FYVE, RhoGEF and PH domain containing 2" "K05721|1|0.0|1323|mmu:26382|FYVE, RhoGEF and PH domain containing 2" GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0043169//cation binding;GO:0008289//lipid binding GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction gi|3599940|gb|AAC35430.1|/0/faciogenital dysplasia protein 2 [Mus musculus] 56699 2970.04 18.00666667 20.24333333 0.168915729 Up 0.344268306 Cdc42ep4 CDC42 effector protein (Rho GTPase binding) 4 K14404|1|1e-20|105|aam:106489093|cleavage and polyadenylation specificity factor subunit 4 GO:0005856//cytoskeleton;GO:0005856//cytoskeleton - GO:0022604//regulation of cell morphogenesis;GO:0031269//pseudopodium assembly;GO:0007265//Ras protein signal transduction;GO:0022604//regulation of cell morphogenesis;GO:0031269//pseudopodium assembly;GO:0007265//Ras protein signal transduction gi|568974988|ref|XP_006533878.1|/4.29756e-168/PREDICTED: cdc42 effector protein 4 isoform X2 [Mus musculus] 108116 3399.78 48.75666667 44.09 -0.14514802 Down 0.344230697 Slco3a1 "solute carrier organic anion transporter family, member 3a1" "K14353|1|0.0|1257|mmu:108116|solute carrier organic anion transporter family, member 3A" GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane GO:0015197//peptide transporter activity;GO:0008509//anion transmembrane transporter activity GO:0044763;GO:0015833//peptide transport;GO:0015908//fatty acid transport gi|84579880|ref|NP_076397.2|/0/solute carrier organic anion transporter family member 3A1 isoform 1 [Mus musculus] 170483 3281 1.77 1.26 -0.490325627 Down 0.34420249 Grin3b "glutamate receptor, ionotropic, NMDA3B" "K05214|1|0.0|1735|mmu:170483|glutamate receptor ionotropic, NMDA 3B" GO:0044297//cell body;GO:0030313//cell envelope;GO:0097060//synaptic membrane;GO:0008328//ionotropic glutamate receptor complex GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0016597//amino acid binding;GO:0038023//signaling receptor activity;GO:0005261//cation channel activity GO:0007215//glutamate receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0006816//calcium ion transport "gi|568966809|ref|XP_006513350.1|/0/PREDICTED: glutamate receptor ionotropic, NMDA 3B isoform X1 [Mus musculus]" 22368 2751 1.413333333 1.94 0.456954888 Up 0.344183685 Trpv2 "transient receptor potential cation channel, subfamily V, member 2" K04971|1|0.0|1397|mmu:22368|transient receptor potential cation channel subfamily V member 2 GO:0030426//growth cone;GO:0048770;GO:0031224//intrinsic component of membrane GO:0005261//cation channel activity;GO:0005488//binding GO:0030307//positive regulation of cell growth;GO:0012501//programmed cell death;GO:0006816//calcium ion transport;GO:0009628//response to abiotic stimulus;GO:0034767//positive regulation of ion transmembrane transport;GO:0006950//response to stress "gi|148678407|gb|EDL10354.1|/0/transient receptor potential cation channel, subfamily V, member 2, isoform CRA_a, partial [Mus musculus]" 211255 4529 1.953333333 1.423333333 -0.456664595 Down 0.344183685 Kbtbd7 kelch repeat and BTB (POZ) domain containing 7 K10474|1|0.0|1268|mmu:211255|kelch repeat and BTB domain-containing protein 6/7 - GO:0005488//binding - gi|254540156|ref|NP_001019306.2|/0/kelch repeat and BTB domain-containing protein 7 [Mus musculus] 56375 2314 10.99 12.56 0.192645078 Up 0.344136673 B4galt4 "UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4" "K07969|1|0.0|686|mmu:56375|beta-1,4-galactosyltransferase 4 [EC:2.4.1.90 2.4.1.275 2.4.1.-]" GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0035250//UDP-galactosyltransferase activity;GO:0043169//cation binding;GO:0035250//UDP-galactosyltransferase activity GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process "gi|148665574|gb|EDK97990.1|/0/UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4, isoform CRA_a, partial [Mus musculus]" 69305 1194 12.86666667 11.29333333 -0.188166973 Down 0.344136673 Dcps "decapping enzyme, scavenger" K12584|1|1e-168|595|mmu:69305|m7GpppX diphosphatase [EC:3.6.1.59] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0000339//RNA cap binding;GO:0016462//pyrophosphatase activity "GO:0012501//programmed cell death;GO:0000398//mRNA splicing, via spliceosome;GO:0071310//cellular response to organic substance;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" "gi|148693430|gb|EDL25377.1|/9.85856e-172/decapping enzyme, scavenger [Mus musculus]" 74098 1551 11.25666667 12.82666667 0.18836662 Up 0.344136673 0610037L13Rik RIKEN cDNA 0610037L13 gene - - - - "gi|148698818|gb|EDL30765.1|/1.44623e-123/RIKEN cDNA 0610037L13, isoform CRA_d, partial [Mus musculus]" 60525 2833 17.64666667 19.87666667 0.171680142 Up 0.344023844 Acss2 acyl-CoA synthetase short-chain family member 2 K01895|1|0.0|1409|mmu:60525|acetyl-CoA synthetase [EC:6.2.1.1] GO:0044424 GO:0032550;GO:0016405//CoA-ligase activity GO:0019541//propionate metabolic process;GO:0006084//acetyl-CoA metabolic process;GO:0006083//acetate metabolic process "gi|148674180|gb|EDL06127.1|/0/acyl-CoA synthetase short-chain family member 2, partial [Mus musculus]" 105943584 2914.33 5.443333333 4.56 -0.255456561 Down 0.343986235 Clk2-scamp3 Clk2-scamp3 readthrough K08823|1|0.0|1009|mmu:105943584|CDC-like kinase [EC:2.7.12.1] - GO:0004672//protein kinase activity GO:0006796//phosphate-containing compound metabolic process gi|840087695|ref|NP_001296945.1|/0/uncharacterized protein LOC105943584 isoform 1 [Mus musculus] 66273 862.13 41.03333333 45.65333333 0.153923845 Up 0.343976833 Aamdc adipogenesis associated Mth938 domain containing K11997|1|8e-09|62.8|bfo:BRAFLDRAFT_85950|tripartite motif-containing protein 2/3 GO:0044424;GO:0044424;GO:0044424;GO:0044424 - GO:0045444//fat cell differentiation;GO:0006915//apoptotic process;GO:0045444//fat cell differentiation;GO:0006915//apoptotic process;GO:0045444//fat cell differentiation;GO:0006915//apoptotic process;GO:0045444//fat cell differentiation;GO:0006915//apoptotic process gi|295789038|ref|NP_001171416.1|/3.82262e-73/mth938 domain-containing protein isoform 1 [Mus musculus] 105511 1694 0.01 0.196666667 4.297680549 Up 0.343948625 Fam170b "family with sequence similarity 170, member B" - - - - "gi|148692899|gb|EDL24846.1|/9.79625e-145/mCG6354, partial [Mus musculus]" 20702 1424 0.196666667 0.01 -4.297680549 Down 0.343948625 Serpina1c "serine (or cysteine) peptidase inhibitor, clade A, member 1C" K03984|1|0.0|760|mmu:20702|alpha-1-antitrypsin - - - gi|6678083|ref|NP_033271.1|/0/alpha-1-antitrypsin 1-3 precursor [Mus musculus] 260408 1253 0.196666667 0.01 -4.297680549 Down 0.343948625 Prss45 "protease, serine 45" K09628|1|8e-47|190|gja:107119121|serine protease 27 [EC:3.4.21.-];K01340|2|6e-45|184|ssc:397389|tryptase [EC:3.4.21.59];K08664|5|9e-44|180|acs:100551951|prostasin [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|23346626|ref|NP_694812.1|/8.92762e-179/inactive serine protease 45 precursor [Mus musculus] 93742 5529.62 10.63 9.243333333 -0.201656481 Down 0.343864004 Pard3 par-3 family cell polarity regulator K04237|1|0.0|2120|rno:81918|partitioning defective protein 3 GO:0032991//macromolecular complex;GO:0030426//growth cone;GO:0070161;GO:0043296//apical junction complex;GO:0015630//microtubule cytoskeleton;GO:0044297//cell body;GO:0043218//compact myelin;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0030426//growth cone;GO:0070161;GO:0043296//apical junction complex;GO:0015630//microtubule cytoskeleton;GO:0044297//cell body;GO:0043218//compact myelin;GO:0044444//cytoplasmic part GO:0019901//protein kinase binding;GO:0043168//anion binding;GO:0019902//phosphatase binding;GO:1901981//phosphatidylinositol phosphate binding;GO:0019901//protein kinase binding;GO:0043168//anion binding;GO:0019902//phosphatase binding;GO:1901981//phosphatidylinositol phosphate binding GO:0007010//cytoskeleton organization;GO:0051640//organelle localization;GO:0007155//cell adhesion;GO:0030029//actin filament-based process;GO:0007043//cell-cell junction assembly;GO:0032879//regulation of localization;GO:0003382//epithelial cell morphogenesis;GO:0006605//protein targeting;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0030010//establishment of cell polarity;GO:0016477//cell migration;GO:0007010//cytoskeleton organization;GO:0051640//organelle localization;GO:0007155//cell adhesion;GO:0030029//actin filament-based process;GO:0007043//cell-cell junction assembly;GO:0032879//regulation of localization;GO:0003382//epithelial cell morphogenesis;GO:0006605//protein targeting;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0030010//establishment of cell polarity;GO:0016477//cell migration gi|823683812|ref|NP_001296321.1|/0/partitioning defective 3 homolog isoform 6 [Mus musculus] 76788 5887.31 10.84333333 9.45 -0.198422087 Down 0.343864004 Klhdc10 kelch domain containing 10 K20285|1|4e-17|94.4|sko:100373945|Rab9 effector protein with kelch motifs;K14966|5|4e-14|84.3|acs:100563537|host cell factor - - - - 56372 1400 25.77666667 28.75333333 0.157663503 Up 0.343685359 1110004F10Rik RIKEN cDNA 1110004F10 gene - - - - gi|9790217|ref|NP_062746.1|/2.49451e-63/small acidic protein [Mus musculus] 15586 2179 4.346666667 3.566666667 -0.285333073 Down 0.343675956 Hyal1 hyaluronoglucosaminidase 1 K01197|1|0.0|913|mmu:15586|hyaluronoglucosaminidase [EC:3.2.1.35] GO:0031982//vesicle;GO:0000323//lytic vacuole;GO:0044421 GO:0005515//protein binding;GO:0015929//hexosaminidase activity;GO:0008194//UDP-glycosyltransferase activity;GO:0004872//receptor activity GO:0001525//angiogenesis;GO:0071363//cellular response to growth factor stimulus;GO:0010631//epithelial cell migration;GO:0007155//cell adhesion;GO:0051130//positive regulation of cellular component organization;GO:0051707//response to other organism;GO:0006027//glycosaminoglycan catabolic process;GO:0009268//response to pH;GO:0009636//response to toxic substance;GO:0008284//positive regulation of cell proliferation;GO:0006024//glycosaminoglycan biosynthetic process;GO:0034612//response to tumor necrosis factor;GO:0010224//response to UV-B;GO:0000084//mitotic S phase;GO:0044238//primary metabolic process;GO:0070555//response to interleukin-1;GO:0016049//cell growth;GO:0036119//response to platelet-derived growth factor;GO:0006952//defense response;GO:0048704//embryonic skeletal system morphogenesis;GO:0006979//response to oxidative stress gi|31982262|ref|NP_032343.2|/0/hyaluronidase-1 precursor [Mus musculus] 59028 1803 3.093333333 3.826666667 0.306925932 Up 0.343544323 Rcl1 RNA terminal phosphate cyclase-like 1 K11108|1|0.0|740|mmu:59028|RNA 3'-terminal phosphate cyclase-like protein GO:0031981//nuclear lumen GO:0009975//cyclase activity GO:0010467//gene expression;GO:0022613//ribonucleoprotein complex biogenesis gi|10946950|ref|NP_067500.1|/0/RNA 3'-terminal phosphate cyclase-like protein [Mus musculus] 235416 1737 0.343333333 0.076666667 -2.162938571 Down 0.343497311 Lman1l "lectin, mannose-binding 1 like" "K10081|1|0.0|917|mmu:235416|lectin, mannose-binding 1-like" GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0031224//intrinsic component of membrane - - gi|157837997|ref|NP_954692.2|/0/protein ERGIC-53-like precursor [Mus musculus] 20937 3105.45 2.81 3.506666667 0.319530168 Up 0.343478506 Suv39h1 suppressor of variegation 3-9 homolog 1 (Drosophila) K11419|1|0.0|872|mmu:20937|histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43] GO:0043234//protein complex;GO:0000792//heterochromatin;GO:0000790//nuclear chromatin;GO:0043234//protein complex;GO:0000792//heterochromatin;GO:0000790//nuclear chromatin GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0018024//histone-lysine N-methyltransferase activity GO:0006342//chromatin silencing;GO:0048869//cellular developmental process;GO:0034968//histone lysine methylation;GO:0042254//ribosome biogenesis;GO:0006342//chromatin silencing;GO:0048869//cellular developmental process;GO:0034968//histone lysine methylation;GO:0042254//ribosome biogenesis gi|6755702|ref|NP_035644.1|/0/histone-lysine N-methyltransferase SUV39H1 isoform 1 [Mus musculus] 21380 1786 0.496666667 0.89 0.841527411 Up 0.343412689 Tbx1 T-box 1 K10175|1|4e-168|593|mmu:21380|T-box protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0003677//DNA binding GO:0048704//embryonic skeletal system morphogenesis;GO:0021564//vagus nerve development;GO:0001932//regulation of protein phosphorylation;GO:0048534//hematopoietic or lymphoid organ development;GO:0008284//positive regulation of cell proliferation;GO:0050954//sensory perception of mechanical stimulus;GO:0003266//regulation of secondary heart field cardioblast proliferation;GO:0034505//tooth mineralization;GO:0001667//ameboidal-type cell migration;GO:0051705;GO:0035981;GO:0003151//outflow tract morphogenesis;GO:0048771//tissue remodeling;GO:0035270//endocrine system development;GO:0035904//aorta development;GO:0035239//tube morphogenesis;GO:0048844//artery morphogenesis;GO:0030522//intracellular receptor signaling pathway;GO:0042472//inner ear morphogenesis;GO:0045165//cell fate commitment;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0003002//regionalization;GO:0071363//cellular response to growth factor stimulus;GO:0043066//negative regulation of apoptotic process;GO:0009855//determination of bilateral symmetry;GO:0000165//MAPK cascade;GO:0048644//muscle organ morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0021564//vagus nerve development;GO:0001932//regulation of protein phosphorylation;GO:0048534//hematopoietic or lymphoid organ development;GO:0008284//positive regulation of cell proliferation;GO:0050954//sensory perception of mechanical stimulus;GO:0003266//regulation of secondary heart field cardioblast proliferation;GO:0034505//tooth mineralization;GO:0001667//ameboidal-type cell migration;GO:0051705;GO:0035981;GO:0003151//outflow tract morphogenesis;GO:0048771//tissue remodeling;GO:0035270//endocrine system development;GO:0035904//aorta development;GO:0035239//tube morphogenesis;GO:0048844//artery morphogenesis;GO:0030522//intracellular receptor signaling pathway;GO:0042472//inner ear morphogenesis;GO:0045165//cell fate commitment;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0003002//regionalization;GO:0071363//cellular response to growth factor stimulus;GO:0043066//negative regulation of apoptotic process;GO:0009855//determination of bilateral symmetry;GO:0000165//MAPK cascade;GO:0048644//muscle organ morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0021564//vagus nerve development;GO:0001932//regulation of protein phosphorylation;GO:0048534//hematopoietic or lymphoid organ development;GO:0008284//positive regulation of cell proliferation;GO:0050954//sensory perception of mechanical stimulus;GO:0003266//regulation of secondary heart field cardioblast proliferation;GO:0034505//tooth mineralization;GO:0001667//ameboidal-type cell migration;GO:0051705;GO:0035981;GO:0003151//outflow tract morphogenesis;GO:0048771//tissue remodeling;GO:0035270//endocrine system development;GO:0035904//aorta development;GO:0035239//tube morphogenesis;GO:0048844//artery morphogenesis;GO:0030522//intracellular receptor signaling pathway;GO:0042472//inner ear morphogenesis;GO:0045165//cell fate commitment;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0003002//regionalization;GO:0071363//cellular response to growth factor stimulus;GO:0043066//negative regulation of apoptotic process;GO:0009855//determination of bilateral symmetry;GO:0000165//MAPK cascade;GO:0048644//muscle organ morphogenesis gi|22094109|ref|NP_035662.1|/1.35351e-161/T-box transcription factor TBX1 isoform 1 [Mus musculus] 67887 1914 132.5766667 146.2633333 0.141741261 Up 0.343384482 Saraf store-operated calcium entry-associated regulatory factor - GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0005262//calcium channel activity GO:0051924//regulation of calcium ion transport gi|19353203|gb|AAH24888.1|/1.27265e-135/Tmem66 protein [Mus musculus] 21767 1571.26 24.81666667 27.75666667 0.161524975 Up 0.343356275 Tex264 testis expressed gene 264 - - - - gi|126090463|ref|NP_001075123.1|/2.39647e-118/testis-expressed sequence 264 protein [Mus musculus] 17191 1866 40.93333333 45.44 0.15068668 Up 0.343356275 Mbd2 methyl-CpG binding domain protein 2 K11590|1|2e-48|195|ptr:455427|methyl-CpG-binding domain protein 2 GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0043234//protein complex GO:0000166//nucleotide binding;GO:0019904//protein domain specific binding;GO:0043565//sequence-specific DNA binding;GO:0003723//RNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0060746//parental behavior;GO:0006461//protein complex assembly;GO:0008283//cell proliferation gi|569003399|ref|XP_006525773.1|/1.44634e-60/PREDICTED: methyl-CpG-binding domain protein 2 isoform X1 [Mus musculus] 20586 6370.28 27.38333333 24.44 -0.164053789 Down 0.343356275 Smarca4 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4" K11647|1|0.0|2276|cge:100756329|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-] GO:0000790//nuclear chromatin;GO:0090544//BAF-type complex;GO:0000790//nuclear chromatin;GO:0090544//BAF-type complex;GO:0000790//nuclear chromatin;GO:0090544//BAF-type complex "GO:0035258//steroid hormone receptor binding;GO:0036094//small molecule binding;GO:0008134//transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0042623//ATPase activity, coupled;GO:0042393//histone binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0035258//steroid hormone receptor binding;GO:0036094//small molecule binding;GO:0008134//transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0042623//ATPase activity, coupled;GO:0042393//histone binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0035258//steroid hormone receptor binding;GO:0036094//small molecule binding;GO:0008134//transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0042623//ATPase activity, coupled;GO:0042393//histone binding;GO:0000976//transcription regulatory region sequence-specific DNA binding" GO:0030326//embryonic limb morphogenesis;GO:0003206//cardiac chamber morphogenesis;GO:0001824//blastocyst development;GO:0030521//androgen receptor signaling pathway;GO:0001709//cell fate determination;GO:0007420//brain development;GO:0043062//extracellular structure organization;GO:0032989;GO:0016049//cell growth;GO:0006342//chromatin silencing;GO:0009154//purine ribonucleotide catabolic process;GO:0043921;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0032776//DNA methylation on cytosine;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006338//chromatin remodeling;GO:0051099//positive regulation of binding;GO:0030218//erythrocyte differentiation;GO:0009913//epidermal cell differentiation;GO:0035886//vascular smooth muscle cell differentiation;GO:0034728//nucleosome organization;GO:0030326//embryonic limb morphogenesis;GO:0003206//cardiac chamber morphogenesis;GO:0001824//blastocyst development;GO:0030521//androgen receptor signaling pathway;GO:0001709//cell fate determination;GO:0007420//brain development;GO:0043062//extracellular structure organization;GO:0032989;GO:0016049//cell growth;GO:0006342//chromatin silencing;GO:0009154//purine ribonucleotide catabolic process;GO:0043921;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0032776//DNA methylation on cytosine;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006338//chromatin remodeling;GO:0051099//positive regulation of binding;GO:0030218//erythrocyte differentiation;GO:0009913//epidermal cell differentiation;GO:0035886//vascular smooth muscle cell differentiation;GO:0034728//nucleosome organization;GO:0030326//embryonic limb morphogenesis;GO:0003206//cardiac chamber morphogenesis;GO:0001824//blastocyst development;GO:0030521//androgen receptor signaling pathway;GO:0001709//cell fate determination;GO:0007420//brain development;GO:0043062//extracellular structure organization;GO:0032989;GO:0016049//cell growth;GO:0006342//chromatin silencing;GO:0009154//purine ribonucleotide catabolic process;GO:0043921;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0032776//DNA methylation on cytosine;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006338//chromatin remodeling;GO:0051099//positive regulation of binding;GO:0030218//erythrocyte differentiation;GO:0009913//epidermal cell differentiation;GO:0035886//vascular smooth muscle cell differentiation;GO:0034728//nucleosome organization gi|291463269|ref|NP_001167549.1|/0/transcription activator BRG1 isoform 1 [Mus musculus] 12169 3005 0.31 0.653333333 1.075551033 Up 0.34333747 Bmx BMX non-receptor tyrosine kinase K08896|1|0.0|1286|mmu:12169|cytoplasmic tyrosine-protein kinase BMX [EC:2.7.10.2] GO:0001726//ruffle;GO:0044424 GO:0043169//cation binding;GO:0032550;GO:0008289//lipid binding;GO:0004713//protein tyrosine kinase activity GO:0012501//programmed cell death;GO:0006468//protein phosphorylation;GO:0022610;GO:0007165//signal transduction gi|226693402|ref|NP_033889.2|/0/cytoplasmic tyrosine-protein kinase BMX [Mus musculus] 68724 1702 27.74666667 24.81333333 -0.16119891 Down 0.343271654 Arl8a ADP-ribosylation factor-like 8A K07955|1|4e-100|367|rno:498234|ADP-ribosylation factor-like protein 8 GO:0005764//lysosome;GO:0005770//late endosome;GO:0005819//spindle GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0015631//tubulin binding GO:0009154//purine ribonucleotide catabolic process;GO:0000087//mitotic M phase;GO:0035556//intracellular signal transduction gi|23956194|ref|NP_081099.1|/3.67396e-99/ADP-ribosylation factor-like protein 8A [Mus musculus] 21953 667 1.366666667 1.886666667 0.465178143 Up 0.343093008 Tnni2 "troponin I, skeletal, fast 2" "K12043|1|6e-91|335|mmu:21953|troponin I, fast skeletal muscle" GO:0043231//intracellular membrane-bounded organelle;GO:0005865//striated muscle thin filament GO:0008092//cytoskeletal protein binding "GO:0006941//striated muscle contraction;GO:0006351//transcription, DNA-templated" "gi|635011204|ref|XP_007999281.1|/1.00757e-91/PREDICTED: troponin I, fast skeletal muscle isoform X3 [Chlorocebus sabaeus]" 235459 889.03 24.09 26.99666667 0.164346892 Up 0.343017789 Gtf2a2 "general transcription factor II A, 2" K03123|1|2e-24|114|cmk:103187798|transcription initiation factor TFIIA small subunit GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex "GO:0001085//RNA polymerase II transcription factor binding;GO:0003712//transcription cofactor activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0003712//transcription cofactor activity;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0008135//translation factor activity, RNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0003712//transcription cofactor activity;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0008135//translation factor activity, RNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0003712//transcription cofactor activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity" GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0044093;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006412//translation;GO:0044093;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006412//translation;GO:0044093;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0044093 gi|116283680|gb|AAH28551.1|/8.23194e-36/Gtf2a2 protein [Mus musculus] 76901 6100 6.06 7.106666667 0.229855239 Up 0.343008387 Jade2 jade family PHD finger 2 K11347|1|0.0|685|pale:102877916|protein Jade-1 - GO:0046914//transition metal ion binding GO:0043967//histone H4 acetylation gi|37359858|dbj|BAC97907.1|/0/mKIAA0239 protein [Mus musculus] 667962 1811 1.223333333 1.726666667 0.497172035 Up 0.342989582 Gm8898 zinc finger protein 966 K09228|1|1e-45|94.0|cge:100753410|KRAB domain-containing zinc finger protein - - - gi|294345440|ref|NP_001170877.1|/0/KRAB box and zinc finger C2H2 type domain containing protein isoform 1 [Mus musculus] 100303732 1811 1.223333333 1.726666667 0.497172035 Up 0.342989582 Gm14431 zinc finger protein 967 K09228|1|0.0|674|cge:103163817|KRAB domain-containing zinc finger protein - - - gi|294345437|ref|NP_001170876.1|/9.58448e-69/KRAB box and zinc finger C2H2 type domain containing protein isoform 2 [Mus musculus] 110172 1169 17.11333333 19.29 0.172732348 Up 0.34298018 Slc35b1 "solute carrier family 35, member B1" "K15275|1|5e-161|569|cge:100756934|solute carrier family 35 (UDP-galactose transporter), member B1" GO:0031224//intrinsic component of membrane - GO:0044765//single-organism transport;GO:0044763 "gi|148684033|gb|EDL15980.1|/6.20244e-163/solute carrier family 35, member B1, isoform CRA_c [Mus musculus]" 240899 1167 9.226666667 10.6 0.200182823 Up 0.342904961 Lrrc52 leucine rich repeat containing 52 K06839|1|8e-25|117|sko:102806385|slit 2 GO:0031224//intrinsic component of membrane GO:0015075//ion transmembrane transporter activity GO:0044765//single-organism transport gi|61656190|ref|NP_001013400.1|/0/leucine-rich repeat-containing protein 52 precursor [Mus musculus] 76938 1583 24.06333333 26.95666667 0.163805607 Up 0.342876754 Rbm17 RNA binding motif protein 17 K12840|1|0.0|689|mmu:76938|splicing factor 45 GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen GO:0036094//small molecule binding;GO:0003676//nucleic acid binding GO:0008380//RNA splicing gi|22779924|ref|NP_690037.1|/0/splicing factor 45 [Mus musculus] 22375 2686.02 24.99333333 27.88666667 0.158032172 Up 0.342876754 Wars tryptophanyl-tRNA synthetase K01867|1|0.0|980|mmu:22375|tryptophanyl-tRNA synthetase [EC:6.1.1.2] GO:0044424;GO:0044424;GO:0044424 GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity GO:0001525//angiogenesis;GO:0006418//tRNA aminoacylation for protein translation;GO:0001525//angiogenesis;GO:0006418//tRNA aminoacylation for protein translation;GO:0001525//angiogenesis;GO:0006418//tRNA aminoacylation for protein translation "gi|256818802|ref|NP_035840.3|/0/tryptophan--tRNA ligase, cytoplasmic isoform 1 [Mus musculus]" 74443 1810 7.883333333 9.11 0.208645276 Up 0.342801534 P4htm "prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)" K06711|1|0.0|1040|rno:301008|hypoxia-inducible factor prolyl 4-hydroxylase [EC:1.14.11.-] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0044710 gi|564310639|ref|XP_001075237.3|/0/PREDICTED: transmembrane prolyl 4-hydroxylase [Rattus norvegicus] 74528 2836 5.4 6.376666667 0.239843061 Up 0.342801534 Mgme1 mitochondrial genome maintainance exonuclease 1 K19465|1|0.0|692|mmu:74528|mitochondrial genome maintenance exonuclease 1 [EC:3.1.-.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0016895//exodeoxyribonuclease activity, producing 5'-phosphomonoesters;GO:0016895//exodeoxyribonuclease activity, producing 5'-phosphomonoesters;GO:0016895//exodeoxyribonuclease activity, producing 5'-phosphomonoesters" GO:0006281//DNA repair;GO:0006281//DNA repair;GO:0006281//DNA repair gi|21312780|ref|NP_083260.1|/0/mitochondrial genome maintenance exonuclease 1 [Mus musculus] 414108 2118 0.803333333 1.24 0.626269475 Up 0.342792132 9230114K14Rik RIKEN cDNA 9230114K14 gene K10591|1|6e-07|58.9|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] - - - - 224796 5870 45.66333333 41.27666667 -0.145709708 Down 0.34274512 Clic5 chloride intracellular channel 5 K05025|1|2e-142|510|mmu:224796|chloride intracellular channel protein 5 GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0005902//microvillus;GO:0034702//ion channel complex;GO:0044444//cytoplasmic part GO:0005254//chloride channel activity;GO:0005488//binding GO:0033036;GO:0044703;GO:0015698//inorganic anion transport;GO:0050954//sensory perception of mechanical stimulus;GO:0002093//auditory receptor cell morphogenesis;GO:0002021//response to dietary excess;GO:0034220//ion transmembrane transport;GO:0050905//neuromuscular process gi|27369886|ref|NP_766209.1|/1.91321e-141/chloride intracellular channel protein 5 [Mus musculus] 23986 1482.98 120.5933333 133.0333333 0.141637624 Up 0.342735718 Eci2 enoyl-Coenzyme A delta isomerase 2 "K13239|1|0.0|729|mmu:23986|peroxisomal 3,2-trans-enoyl-CoA isomerase [EC:5.3.3.8]" GO:0044439;GO:0044439;GO:0044439 "GO:0005515//protein binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds;GO:0005515//protein binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds;GO:0005515//protein binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds" GO:0009062//fatty acid catabolic process;GO:0009062//fatty acid catabolic process;GO:0009062//fatty acid catabolic process "gi|160333193|ref|NP_001103801.1|/0/enoyl-CoA delta isomerase 2, mitochondrial isoform a [Mus musculus]" 66179 1243 11.04333333 12.58 0.18795622 Up 0.342735718 Ogfod3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 - GO:0031224//intrinsic component of membrane "GO:0046914//transition metal ion binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0019842//vitamin binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0044710 gi|13384786|ref|NP_079678.1|/7.80977e-151/2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 [Mus musculus] 74486 1872 1.54 2.083333333 0.435963338 Up 0.342698108 Osbpl10 oxysterol binding protein-like 10 K20465|1|0.0|1126|mmu:74486|oxysterol-binding protein-related protein 9/10/11 - GO:0032934//sterol binding GO:0051234//establishment of localization;GO:0010876//lipid localization gi|755532381|ref|XP_011241354.1|/0/PREDICTED: oxysterol-binding protein-related protein 10 isoform X4 [Mus musculus] 53902 5062 2.39 1.806666667 -0.403680267 Down 0.342632292 Rcan3 regulator of calcineurin 3 K17905|1|2e-113|413|mmu:53902|calcipression-3 - GO:0008092//cytoskeletal protein binding GO:0019932//second-messenger-mediated signaling gi|12667790|ref|NP_075356.1|/2.07966e-112/calcipressin-3 [Mus musculus] 19279 2508 1.32 0.873333333 -0.595933619 Down 0.342632292 Ptprr "protein tyrosine phosphatase, receptor type, R" K04458|1|0.0|1290|mmu:19279|receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48] GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen GO:0019900//kinase binding;GO:0004725//protein tyrosine phosphatase activity;GO:0019900//kinase binding;GO:0004721//phosphoprotein phosphatase activity;GO:0019900//kinase binding;GO:0004721//phosphoprotein phosphatase activity;GO:0019900//kinase binding;GO:0004721//phosphoprotein phosphatase activity;GO:0019900//kinase binding;GO:0004721//phosphoprotein phosphatase activity GO:0048731//system development;GO:0006470//protein dephosphorylation;GO:0043009//chordate embryonic development;GO:0030154//cell differentiation;GO:0048731//system development;GO:0006470//protein dephosphorylation;GO:0043009//chordate embryonic development;GO:0030154//cell differentiation;GO:0048731//system development;GO:0006470//protein dephosphorylation;GO:0043009//chordate embryonic development;GO:0030154//cell differentiation;GO:0048731//system development;GO:0006470//protein dephosphorylation;GO:0043009//chordate embryonic development;GO:0030154//cell differentiation;GO:0048731//system development;GO:0006470//protein dephosphorylation;GO:0043009//chordate embryonic development;GO:0030154//cell differentiation gi|320461570|ref|NP_001155309.1|/0/receptor-type tyrosine-protein phosphatase R isoform b [Mus musculus] 29876 4065 130.9866667 118.86 -0.140156679 Down 0.342604084 Clic4 chloride intracellular channel 4 (mitochondrial) K05024|1|2e-143|513|mmu:29876|chloride intracellular channel protein 4 GO:0012506//vesicle membrane;GO:0005815//microtubule organizing center;GO:0034399//nuclear periphery;GO:0034702//ion channel complex;GO:0042995//cell projection;GO:0030054//cell junction;GO:0044444//cytoplasmic part GO:0005254//chloride channel activity;GO:0005515//protein binding GO:0007010//cytoskeleton organization;GO:0040007//growth;GO:0015698//inorganic anion transport;GO:0051592//response to calcium ion;GO:0001885//endothelial cell development;GO:0009913//epidermal cell differentiation;GO:0019953//sexual reproduction;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0060562//epithelial tube morphogenesis;GO:0051452//intracellular pH reduction;GO:0034220//ion transmembrane transport;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0016477//cell migration gi|7304963|ref|NP_038913.1|/1.98651e-142/chloride intracellular channel protein 4 [Mus musculus] 217707 1602 40.62666667 44.99666667 0.147391132 Up 0.342594682 Coq6 coenzyme Q6 monooxygenase K06126|1|0.0|924|mmu:217707|ubiquinone biosynthesis monooxygenase Coq6 [EC:1.14.13.-] - - - - 634650 2720 0.086666667 0.353333333 2.027480736 Up 0.34258528 Gbp11 guanylate binding protein 11 K17339|1|5e-17|92.8|lcm:102358552|atlastin [EC:3.6.5.-] GO:0031982//vesicle;GO:0020003//symbiont-containing vacuole GO:0005488//binding GO:0032496//response to lipopolysaccharide;GO:0001562//response to protozoan;GO:0042742//defense response to bacterium;GO:0002697;GO:0001932//regulation of protein phosphorylation;GO:0016567//protein ubiquitination;GO:0032480//negative regulation of type I interferon production;GO:0034341//response to interferon-gamma;GO:0051702//interaction with symbiont;GO:0006606//protein import into nucleus;GO:0035456//response to interferon-beta gi|829496033|ref|NP_001034736.3|/0/guanylate binding protein 11 [Mus musculus] 72477 4631 3.41 4.183333333 0.294881219 Up 0.342519463 Tmem87b transmembrane protein 87B - GO:0031224//intrinsic component of membrane - - gi|124487303|ref|NP_082524.2|/0/transmembrane protein 87B precursor [Mus musculus] 67067 472.42 118.3166667 130.2433333 0.138556215 Up 0.342453646 Romo1 reactive oxygen species modulator 1 K04487|1|1e-06|54.3|cjo:107322813|cysteine desulfurase [EC:2.8.1.7] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane - GO:0006952//defense response;GO:0000302//response to reactive oxygen species;GO:0072593//reactive oxygen species metabolic process;GO:0007569//cell aging;GO:0008283//cell proliferation;GO:0006952//defense response;GO:0000302//response to reactive oxygen species;GO:0072593//reactive oxygen species metabolic process;GO:0007569//cell aging;GO:0008283//cell proliferation;GO:0006952//defense response;GO:0000302//response to reactive oxygen species;GO:0072593//reactive oxygen species metabolic process;GO:0007569//cell aging;GO:0008283//cell proliferation gi|528758629|gb|EPY78288.1|/1.95653e-30/hypothetical protein CB1_001108037 [Camelus ferus] 18128 9497 12.62666667 11.09666667 -0.18634746 Down 0.34231261 Notch1 notch 1 K02599|1|0.0|5216|mmu:18128|Notch GO:0043234//protein complex;GO:0030141//secretory granule;GO:0016021//integral component of membrane "GO:0046872//metal ion binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0044212//transcription regulatory region DNA binding;GO:0030234//enzyme regulator activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003682//chromatin binding;GO:0005515//protein binding" GO:0006955//immune response;GO:0044092//negative regulation of molecular function;GO:0002011//morphogenesis of an epithelial sheet;GO:0001837//epithelial to mesenchymal transition;GO:0045687//positive regulation of glial cell differentiation;GO:0060837//blood vessel endothelial cell differentiation;GO:0003183//mitral valve morphogenesis;GO:0009855//determination of bilateral symmetry;GO:0002237//response to molecule of bacterial origin;GO:0003177;GO:0003143//embryonic heart tube morphogenesis;GO:0030858//positive regulation of epithelial cell differentiation;GO:0014855;GO:0001942//hair follicle development;GO:0003266//regulation of secondary heart field cardioblast proliferation;GO:0042491//auditory receptor cell differentiation;GO:0003176//aortic valve development;GO:0001525//angiogenesis;GO:0007219//Notch signaling pathway;GO:0072006//nephron development;GO:0043066//negative regulation of apoptotic process;GO:0002067//glandular epithelial cell differentiation;GO:0008284//positive regulation of cell proliferation;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006954//inflammatory response;GO:0030216//keratinocyte differentiation;GO:1901652//response to peptide;GO:0008285//negative regulation of cell proliferation;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:0021510//spinal cord development;GO:0050678//regulation of epithelial cell proliferation;GO:0032633//interleukin-4 production;GO:0048232//male gamete generation;GO:0003281//ventricular septum development;GO:0048545//response to steroid hormone;GO:0001756//somitogenesis;GO:0017156//calcium ion regulated exocytosis;GO:0003211//cardiac ventricle formation;GO:0048845//venous blood vessel morphogenesis;GO:0032354//response to follicle-stimulating hormone;GO:0003272//endocardial cushion formation;GO:0001649//osteoblast differentiation;GO:0002328//pro-B cell differentiation;GO:0048844//artery morphogenesis;GO:0007420//brain development;GO:0009798//axis specification;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0003161//cardiac conduction system development;GO:0060379//cardiac muscle cell myoblast differentiation;GO:0030326//embryonic limb morphogenesis;GO:0045665//negative regulation of neuron differentiation;GO:0045686//negative regulation of glial cell differentiation;GO:0030509//BMP signaling pathway;GO:0016477//cell migration;GO:0044087;GO:0045165//cell fate commitment;GO:0003157//endocardium development;GO:0003209//cardiac atrium morphogenesis;GO:0009967//positive regulation of signal transduction;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030323//respiratory tube development;GO:0019827//stem cell population maintenance;GO:0003171//atrioventricular valve development;GO:0007405//neuroblast proliferation;GO:0007259//JAK-STAT cascade;GO:0017145//stem cell division;GO:0045445//myoblast differentiation;GO:0007162//negative regulation of cell adhesion;GO:0010830//regulation of myotube differentiation;GO:0061383//trabecula morphogenesis;GO:0001570//vasculogenesis;GO:0055006//cardiac cell development gi|224967065|ref|NP_032740.3|/0/neurogenic locus notch homolog protein 1 precursor [Mus musculus] 66161 1214 10.66333333 9.3 -0.19735587 Down 0.34231261 Pop4 "processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae)" K03538|1|7e-114|412|mmu:66161|ribonuclease P protein subunit POP4 [EC:3.1.26.5] GO:0043231//intracellular membrane-bounded organelle;GO:0005732//small nucleolar ribonucleoprotein complex;GO:0030681//multimeric ribonuclease P complex GO:0004549//tRNA-specific ribonuclease activity;GO:0003676//nucleic acid binding GO:0042254//ribosome biogenesis;GO:0006399//tRNA metabolic process;GO:0006397//mRNA processing gi|13384772|ref|NP_079666.1|/6.24707e-113/ribonuclease P protein subunit p29 [Mus musculus] 14370 3346 2.993333333 2.35 -0.349092187 Down 0.342303208 Fzd8 frizzled class receptor 8 K02375|1|0.0|790|rno:100909849|frizzled 5/8 - - - - 11933 1833 24.69333333 27.53666667 0.157232333 Up 0.342256196 Atp1b3 "ATPase, Na+/K+ transporting, beta 3 polypeptide" K01540|1|2e-162|575|mmu:11933|sodium/potassium-transporting ATPase subunit beta GO:0048770;GO:0005887//integral component of plasma membrane GO:0005488//binding;GO:0008556//potassium-transporting ATPase activity GO:0044763;GO:0002376//immune system process;GO:0007599//hemostasis;GO:0030001//metal ion transport gi|6680744|ref|NP_031528.1|/1.6707e-161/sodium/potassium-transporting ATPase subunit beta-3 [Mus musculus] 68922 2508 0.786666667 0.413333333 -0.928446739 Down 0.342218587 Dnaic1 "dynein, axonemal, intermediate chain 1" "K10409|1|0.0|1315|mmu:68922|dynein intermediate chain 1, axonemal" GO:0005875//microtubule associated complex;GO:0005930//axoneme GO:0005488//binding;GO:0017111//nucleoside-triphosphatase activity GO:0003341//cilium movement "gi|227330593|ref|NP_780347.2|/0/dynein intermediate chain 1, axonemal [Mus musculus]" 56305 2785.62 23.84 26.67333333 0.162013892 Up 0.34215277 Pitpnb "phosphatidylinositol transfer protein, beta" - GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0005488//binding;GO:0005548//phospholipid transporter activity;GO:0005548//phospholipid transporter activity;GO:0005488//binding;GO:0005488//binding;GO:0005548//phospholipid transporter activity;GO:0005488//binding;GO:0005548//phospholipid transporter activity GO:0043009//chordate embryonic development;GO:0006869//lipid transport;GO:0006650//glycerophospholipid metabolic process;GO:0043009//chordate embryonic development;GO:0051234//establishment of localization;GO:0043009//chordate embryonic development;GO:0006869//lipid transport;GO:0006650//glycerophospholipid metabolic process;GO:0043009//chordate embryonic development;GO:0006869//lipid transport;GO:0006650//glycerophospholipid metabolic process gi|9790159|ref|NP_062614.1|/4.0785e-144/phosphatidylinositol transfer protein beta isoform isoform 2 [Mus musculus] 230751 2152 0.996666667 1.463333333 0.554075455 Up 0.342105758 Oscp1 organic solute carrier partner 1 - - - - - 73431 2414 2.096666667 2.706666667 0.36841971 Up 0.342030539 1700052K11Rik RIKEN cDNA 1700052K11 gene - - - - gi|74201765|dbj|BAE28491.1|/8.01678e-61/unnamed protein product [Mus musculus] 19357 3632 26.92333333 24.1 -0.159823892 Down 0.342021137 Rad21 RAD21 cohesin complex component K06670|1|0.0|1110|mmu:19357|cohesin complex subunit SCC1 - - - - 57431 841 38.96 43.22333333 0.149816658 Up 0.341964722 Dnajc4 DnaJ heat shock protein family (Hsp40) member C4 K09524|1|5e-116|419|mmu:57431|DnaJ homolog subfamily C member 4 - - - - 72482 1113.74 39.35666667 43.62 0.148381734 Up 0.341964722 Acbd6 acyl-Coenzyme A binding domain containing 6 "K17481|1|3e-13|79.0|crg:105332686|myosin XVI;K08762|2|1e-12|77.4|cmy:102944953|diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein)" GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0043168//anion binding;GO:0005488//binding;GO:0005488//binding - gi|224809391|ref|NP_001139253.1|/1.52925e-61/acyl-CoA-binding domain-containing protein 6 isoform 2 [Mus musculus] 100126224 1648 3.72 3.003333333 -0.308738016 Down 0.341936515 Gm11747 predicted gene 11747 K19470|1|3e-25|119|cjo:107313831|complement C1q tumor necrosis factor-related protein 6 - - - - 244329 4636 1.74 2.306666667 0.406722231 Up 0.341880101 Mcph1 "microcephaly, primary autosomal recessive 1" K19403|1|0.0|1559|mmu:244329|microcephalin GO:0043232 - GO:0044380//protein localization to cytoskeleton;GO:0021543//pallium development;GO:0030261//chromosome condensation;GO:0042325//regulation of phosphorylation;GO:0019827//stem cell population maintenance;GO:0007098//centrosome cycle;GO:0010467//gene expression gi|37059803|ref|NP_775281.2|/0/microcephalin [Mus musculus] 224893 2059 1.346666667 0.896666667 -0.58674912 Down 0.341851894 Zfp959 zinc finger protein 959 K09228|1|0.0|1187|mmu:224893|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|21729792|ref|NP_663465.1|/0/uncharacterized protein LOC224893 [Mus musculus] 212531 3501 1.336666667 0.89 -0.586762495 Down 0.341851894 Sh3bgrl2 SH3 domain binding glutamic acid-rich protein like 2 "K03877|1|5e-32|142|tgu:100227439|beta-1,3-galactosyltransferase 5 [EC:2.4.1.-];K13912|2|3e-09|67.4|xma:102221819|deleted in malignant brain tumors 1 protein" GO:0043231//intracellular membrane-bounded organelle GO:0019904//protein domain specific binding - gi|880900156|ref|XP_012971516.1|/1.90098e-61/PREDICTED: SH3 domain-binding glutamic acid-rich-like protein 2 [Mesocricetus auratus] 216150 1295 103.2066667 114.03 0.143877266 Up 0.341645041 Cdc34 cell division cycle 34 K02207|1|4e-115|417|rno:299602|ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23] GO:0031981//nuclear lumen GO:0032550;GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination;GO:0044772//mitotic cell cycle phase transition;GO:0051130//positive regulation of cellular component organization;GO:0010033//response to organic substance;GO:0009968//negative regulation of signal transduction;GO:0006259//DNA metabolic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0043065//positive regulation of apoptotic process gi|829957661|ref|XP_012601344.1|/3.63391e-114/PREDICTED: ubiquitin-conjugating enzyme E2 R1 [Microcebus murinus] 19175 1036 107.6233333 118.4333333 0.138084292 Up 0.341635639 Psmb6 "proteasome (prosome, macropain) subunit, beta type 6" K02738|1|3e-106|387|mmu:19175|20S proteasome subunit beta 1 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity GO:0006508//proteolysis gi|74204932|dbj|BAE20959.1|/1.62141e-108/unnamed protein product [Mus musculus] 64339 2270 1.223333333 1.72 0.491591003 Up 0.341466396 Fndc4 fibronectin type III domain containing 4 K05120|1|6e-08|62.4|cmk:103174620|tyrosine kinase receptor 1 [EC:2.7.10.1] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|83921579|ref|NP_071869.2|/8.35925e-129/fibronectin type III domain-containing protein 4 precursor [Mus musculus] 50884 4403 18.49333333 16.38666667 -0.174482872 Down 0.341428786 Nckap1 NCK-associated protein 1 K05750|1|0.0|2203|mmu:50884|NCK-associated protein 1 GO:0030027//lamellipodium;GO:0044424;GO:0031224//intrinsic component of membrane GO:0005488//binding "GO:0014020;GO:0031647//regulation of protein stability;GO:0012501//programmed cell death;GO:0001667//ameboidal-type cell migration;GO:0030903//notochord development;GO:0007440//foregut morphogenesis;GO:0030036//actin cytoskeleton organization;GO:0008105//asymmetric protein localization;GO:0030031//cell projection assembly;GO:0008595//anterior/posterior axis specification, embryo;GO:0010171//body morphogenesis;GO:0007509//mesoderm migration involved in gastrulation" gi|595582321|ref|NP_001277674.1|/0/nck-associated protein 1 isoform a [Mus musculus] 70439 2049 7.57 8.776666667 0.213379815 Up 0.341400579 Taf15 TATA-box binding protein associated factor 15 K14651|1|1e-124|256|rno:287571|transcription initiation factor TFIID subunit 15 - - - gi|157786842|ref|NP_001099294.1|/1.04236e-123/TATA-binding protein-associated factor 2N [Rattus norvegicus] 83964 1986 7.606666667 8.816666667 0.212968931 Up 0.341400579 Jam3 junction adhesion molecule 3 K06785|1|1e-155|552|mmu:83964|junctional adhesion molecule 3 GO:0043296//apical junction complex;GO:0043218//compact myelin;GO:0031224//intrinsic component of membrane;GO:0044421 GO:0005102//receptor binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding GO:0007163//establishment or maintenance of cell polarity;GO:0006955//immune response;GO:0016337//single organismal cell-cell adhesion;GO:0031589//cell-substrate adhesion;GO:0007281//germ cell development;GO:0048232//male gamete generation;GO:0006954//inflammatory response;GO:0008366//axon ensheathment;GO:0002244//hematopoietic progenitor cell differentiation;GO:0002688//regulation of leukocyte chemotaxis;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0001776//leukocyte homeostasis gi|12963613|ref|NP_075766.1|/9.81353e-155/junctional adhesion molecule C precursor [Mus musculus] 12497 2500 8.926666667 10.26666667 0.20177439 Up 0.34136297 Entpd6 ectonucleoside triphosphate diphosphohydrolase 6 K01511|1|0.0|853|mmu:12497|ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6] GO:0044421;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0017110//nucleoside-diphosphatase activity GO:0010038//response to metal ion gi|83921570|ref|NP_742115.2|/0/ectonucleoside triphosphate diphosphohydrolase 6 [Mus musculus] 215015 4238 26.44 23.68333333 -0.158850028 Down 0.341287751 Fam20b "family with sequence similarity 20, member B" K19347|1|2e-56|224|ccw:104696523|SUN domain-containing protein 1/2;K00327|2|2e-48|197|tsp:Tsp_02446|NADPH-ferrihemoprotein reductase [EC:1.6.2.4] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0032550;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006796//phosphate-containing compound metabolic process gi|537169371|gb|ERE73927.1|/0/glycosaminoglycan xylosylkinase-like protein [Cricetulus griseus] 228998 2676.73 13.54666667 15.29666667 0.175279405 Up 0.341193727 Arfgap1 ADP-ribosylation factor GTPase activating protein 1 K12492|1|0.0|651|mmu:228998|ADP-ribosylation factor GTPase-activating protein 1 GO:0016020//membrane;GO:0005635//nuclear envelope;GO:0016020//membrane;GO:0005635//nuclear envelope;GO:0016020//membrane;GO:0005635//nuclear envelope;GO:0016020//membrane;GO:0005635//nuclear envelope;GO:0016020//membrane;GO:0005635//nuclear envelope GO:0030695//GTPase regulator activity;GO:0008047//enzyme activator activity;GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0008047//enzyme activator activity;GO:0046872//metal ion binding;GO:0030695//GTPase regulator activity;GO:0008047//enzyme activator activity;GO:0046872//metal ion binding;GO:0030695//GTPase regulator activity;GO:0008047//enzyme activator activity;GO:0046872//metal ion binding;GO:0030695//GTPase regulator activity;GO:0008047//enzyme activator activity;GO:0046872//metal ion binding GO:0043087//regulation of GTPase activity;GO:0006810//transport;GO:0043087//regulation of GTPase activity;GO:0006810//transport;GO:0043087//regulation of GTPase activity;GO:0006810//transport;GO:0043087//regulation of GTPase activity;GO:0006810//transport;GO:0043087//regulation of GTPase activity;GO:0006810//transport "gi|148675423|gb|EDL07370.1|/0/ADP-ribosylation factor GTPase activating protein 1, isoform CRA_f, partial [Mus musculus]" 235623 4171.81 15.06666667 13.31333333 -0.17848844 Down 0.341193727 Scap SREBF chaperone K16302|1|2e-25|121|pxy:105394097|metal transporter CNNM;K10260|2|2e-16|91.3|pon:100173626|F-box and WD-40 domain protein 7 GO:0032991//macromolecular complex;GO:0012507//ER to Golgi transport vesicle membrane;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0012507//ER to Golgi transport vesicle membrane;GO:0031224//intrinsic component of membrane GO:0005515//protein binding;GO:0032934//sterol binding;GO:0005515//protein binding;GO:0032934//sterol binding GO:0006984//ER-nucleus signaling pathway;GO:0034067//protein localization to Golgi apparatus;GO:0006633//fatty acid biosynthetic process;GO:0043434//response to peptide hormone;GO:0006695//cholesterol biosynthetic process;GO:0044767//single-organism developmental process;GO:0006950//response to stress;GO:0006606//protein import into nucleus;GO:0035459//cargo loading into vesicle;GO:0006984//ER-nucleus signaling pathway;GO:0034067//protein localization to Golgi apparatus;GO:0006633//fatty acid biosynthetic process;GO:0043434//response to peptide hormone;GO:0006695//cholesterol biosynthetic process;GO:0044767//single-organism developmental process;GO:0006950//response to stress;GO:0006606//protein import into nucleus;GO:0035459//cargo loading into vesicle "gi|148677071|gb|EDL09018.1|/0/SREBP cleavage activating protein, isoform CRA_a, partial [Mus musculus]" 105428 2295.13 14.73666667 12.98333333 -0.182749406 Down 0.341193727 Fam149b "family with sequence similarity 149, member B" - - - - "gi|148669573|gb|EDL01520.1|/0/expressed sequence AA536717, isoform CRA_c, partial [Mus musculus]" 17083 1502.45 23.15333333 25.90666667 0.16210349 Up 0.341174922 Tmed1 transmembrane emp24 domain containing 1 K20348|1|2e-50|202|cge:100757205|p24 family protein gamma-1 - - - - 100042539 3558 0.603333333 0.276666667 -1.124806456 Down 0.341080898 Gm3893 predicted gene 3893 - - - - gi|148670565|gb|EDL02512.1|/0/mCG1041302 [Mus musculus] 68742 960.47 6.74 7.84 0.218105063 Up 0.34096807 Tmem219 transmembrane protein 219 - GO:0016020//membrane;GO:0016020//membrane - - gi|568951301|ref|XP_006508218.1|/7.10405e-108/PREDICTED: insulin-like growth factor-binding protein 3 receptor isoform X2 [Mus musculus] 75420 3327 6.593333333 7.696666667 0.223225747 Up 0.34096807 Secisbp2 SECIS binding protein 2 K19539|1|0.0|1439|rno:79049|selenocysteine insertion sequence-binding protein 2 - - - - 242785 3895 38.42666667 42.50666667 0.145581294 Up 0.340864643 Klhl21 kelch-like 21 K10458|1|0.0|1201|mmu:242785|kelch-like protein 21 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0000922//spindle pole GO:0019787//ubiquitin-like protein transferase activity GO:0032446//protein modification by small protein conjugation;GO:0000087//mitotic M phase gi|74196490|dbj|BAE34380.1|/0/unnamed protein product [Mus musculus] 56229 4378.04 4.506666667 3.716666667 -0.278051441 Down 0.340845839 Thsd1 "thrombospondin, type I, domain 1" K06841|1|9e-08|62.8|tad:TRIADDRAFT_53875|semaphorin 5;K08624|2|9e-08|62.8|tca:660604|a disintegrin and metalloproteinase with thrombospondin motifs 9 [EC:3.4.24.-];K17341|3|6e-07|60.1|dre:559150|hemicentin;K04597|4|1e-06|59.3|asn:102368972|brain-specific angiogenesis inhibitor 2;K16857|5|2e-06|58.5|mze:101487021|thrombospondin 1 GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane - - gi|654822351|ref|NP_001280617.1|/0/thrombospondin type-1 domain-containing protein 1 isoform 3 precursor [Mus musculus] 241494 3133.57 1.646666667 2.2 0.417954983 Up 0.340817631 Zfp385b zinc finger protein 385B - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - gi|164663783|ref|NP_001106870.1|/0/zinc finger protein 385B isoform 2 [Mus musculus] 16825 2121.63 38.01666667 42.06666667 0.146045464 Up 0.340714205 Ldb1 LIM domain binding 1 K15617|1|0.0|758|pale:102896565|LIM domain-binding protein 1 GO:0000785//chromatin;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0030054//cell junction;GO:0000785//chromatin;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0030054//cell junction GO:0003712//transcription cofactor activity;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0000976//transcription regulatory region sequence-specific DNA binding "GO:0007166//cell surface receptor signaling pathway;GO:0008544//epidermis development;GO:0007369//gastrulation;GO:0007155//cell adhesion;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0021533//cell differentiation in hindbrain;GO:0019827//stem cell population maintenance;GO:0009798//axis specification;GO:0030218//erythrocyte differentiation;GO:0006354//DNA-templated transcription, elongation;GO:0022037//metencephalon development;GO:0043966//histone H3 acetylation;GO:0001894//tissue homeostasis;GO:0007166//cell surface receptor signaling pathway;GO:0008544//epidermis development;GO:0007369//gastrulation;GO:0007155//cell adhesion;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0021533//cell differentiation in hindbrain;GO:0019827//stem cell population maintenance;GO:0009798//axis specification;GO:0030218//erythrocyte differentiation;GO:0006354//DNA-templated transcription, elongation;GO:0022037//metencephalon development;GO:0043966//histone H3 acetylation;GO:0001894//tissue homeostasis" gi|528762916|gb|EPY82575.1|/0/LIM domain-binding protein 1 isoform 2-like protein [Camelus ferus] 26406 3161 18.77 16.69333333 -0.169156589 Down 0.340676596 Map3k3 mitogen-activated protein kinase kinase kinase 3 K04421|1|0.0|1259|mmu:26406|mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25] - GO:0043169//cation binding;GO:0032550;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0006468//protein phosphorylation;GO:0007249//I-kappaB kinase/NF-kappaB signaling "gi|148702316|gb|EDL34263.1|/0/mitogen activated protein kinase kinase kinase 3, isoform CRA_b, partial [Mus musculus]" 68291 2364 12.97333333 14.70333333 0.18059405 Up 0.340676596 Mto1 mitochondrial tRNA translation optimization 1 K03495|1|0.0|1208|mmu:68291|tRNA uridine 5-carboxymethylaminomethyl modification enzyme GO:0043231//intracellular membrane-bounded organelle GO:0000166//nucleotide binding GO:0044710;GO:0002098//tRNA wobble uridine modification "gi|171460946|ref|NP_080934.2|/0/protein MTO1 homolog, mitochondrial precursor [Mus musculus]" 73442 5757.83 5.076666667 4.23 -0.263223873 Down 0.340667193 Hspa12a heat shock protein 12A K03283|1|5e-06|57.4|tca:655234|heat shock 70kDa protein 1/8 - GO:0032550 - gi|26006161|dbj|BAC41423.1|/0/mKIAA0417 protein [Mus musculus] 232341 9848.82 39.88333333 35.84666667 -0.15394702 Down 0.340667193 Wnk1 WNK lysine deficient protein kinase 1 K08867|1|0.0|1809|aml:100475299|WNK lysine deficient protein kinase [EC:2.7.11.1] GO:0044424;GO:0044424 GO:0032550;GO:0004672//protein kinase activity;GO:0008200//ion channel inhibitor activity;GO:0046872//metal ion binding;GO:0004860//protein kinase inhibitor activity;GO:0019900//kinase binding;GO:0032550;GO:0004672//protein kinase activity;GO:0008200//ion channel inhibitor activity;GO:0046872//metal ion binding;GO:0004860//protein kinase inhibitor activity;GO:0019900//kinase binding GO:0051048//negative regulation of secretion;GO:0003073//regulation of systemic arterial blood pressure;GO:0006469//negative regulation of protein kinase activity;GO:0010921//regulation of phosphatase activity;GO:0035556//intracellular signal transduction;GO:0051048//negative regulation of secretion;GO:0003073//regulation of systemic arterial blood pressure;GO:0006469//negative regulation of protein kinase activity;GO:0010921//regulation of phosphatase activity;GO:0035556//intracellular signal transduction gi|312283629|ref|NP_001186012.1|/0/serine/threonine-protein kinase WNK1 isoform 4 [Mus musculus] 17000 2109 22.62333333 25.31666667 0.162275952 Up 0.340469743 Ltbr lymphotoxin B receptor K03159|1|0.0|716|mmu:17000|lymphotoxin beta receptor TNFR superfamily member 3 GO:0031224//intrinsic component of membrane GO:0044389//ubiquitin-like protein ligase binding GO:0007254//JNK cascade;GO:0048534//hematopoietic or lymphoid organ development;GO:0097191//extrinsic apoptotic signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0009612//response to mechanical stimulus gi|74222224|dbj|BAE26920.1|/0/unnamed protein product [Mus musculus] 19132 1769 0.306666667 0.056666667 -2.436099115 Down 0.340403926 Prph peripherin K07607|1|0.0|711|mmu:19132|peripherin GO:0030424//axon;GO:0005882//intermediate filament;GO:0044297//cell body;GO:0001750//photoreceptor outer segment;GO:0030424//axon;GO:0005882//intermediate filament;GO:0044297//cell body;GO:0001750//photoreceptor outer segment;GO:0030424//axon;GO:0005882//intermediate filament;GO:0044297//cell body;GO:0001750//photoreceptor outer segment GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization gi|254675335|ref|NP_038667.2|/0/peripherin isoform 1 [Mus musculus] 328967 3234 2.576666667 1.983333333 -0.377578746 Down 0.340394524 Arhgef37 Rho guanine nucleotide exchange factor (GEF) 37 "K12365|1|3e-20|103|ggo:101149045|phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein" GO:0044424 GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0007266//Rho protein signal transduction gi|160333547|ref|NP_808496.2|/0/rho guanine nucleotide exchange factor 37 [Mus musculus] 19204 3660 1.673333333 1.186666667 -0.495810123 Down 0.340375719 Ptafr platelet-activating factor receptor K04279|1|0.0|639|mmu:19204|platelet-activating factor receptor - - - - 100502742 747 1.173333333 1.663333333 0.503464387 Up 0.340375719 1700007L15Rik RIKEN cDNA 1700007L15 gene - - - - - 23881 4258.54 14.87 13.15333333 -0.176976192 Down 0.340366317 G3bp2 GTPase activating protein (SH3 domain) binding protein 2 K17265|1|1e-127|461|cmk:103184137|Ras GTPase-activating protein-binding protein 1 [EC:3.6.4.12 3.6.4.13] GO:0044424;GO:0044424 - GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction gi|74216966|dbj|BAE26595.1|/0/unnamed protein product [Mus musculus] 67711 1082 23.07 25.74666667 0.15836766 Up 0.34033811 Nsmce1 "NSE1 homolog, SMC5-SMC6 complex component" - GO:0043231//intracellular membrane-bounded organelle;GO:0000793//condensed chromosome GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0006259//DNA metabolic process;GO:0032446//protein modification by small protein conjugation;GO:0007165//signal transduction;GO:0006974//cellular response to DNA damage stimulus gi|34328291|ref|NP_080606.2|/5.1557e-161/non-structural maintenance of chromosomes element 1 homolog [Mus musculus] 100503469 640 0.96 1.42 0.564784619 Up 0.340168867 Gm19710 "predicted gene, 19710" - - - - - 71785 1795 6.32 5.37 -0.23500247 Down 0.340093648 Pdgfd "platelet-derived growth factor, D polypeptide" K05450|1|0.0|749|mmu:71785|platelet derived growth factor C/D GO:0044421 GO:0005102//receptor binding GO:0001932//regulation of protein phosphorylation;GO:0048522;GO:0043200//response to amino acid;GO:0032502//developmental process gi|27229137|ref|NP_082200.1|/0/platelet-derived growth factor D precursor [Mus musculus] 20515 3239.63 5.25 6.203333333 0.240726227 Up 0.340093648 Slc20a1 "solute carrier family 20, member 1" K14640|1|0.0|1355|mmu:20515|solute carrier family 20 (sodium-dependent phosphate transporter) GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0060089;GO:0005436//sodium:phosphate symporter activity;GO:0060089;GO:0005436//sodium:phosphate symporter activity GO:0015698//inorganic anion transport;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0030001//metal ion transport;GO:0015698//inorganic anion transport;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0030001//metal ion transport gi|7657579|ref|NP_056562.1|/0/sodium-dependent phosphate transporter 1 isoform 1 [Mus musculus] 93885 3438 0.383333333 0.743333333 0.955409849 Up 0.340065441 Pcdhb14 protocadherin beta 14 K16494|1|0.0|1468|mmu:93885|protocadherin beta GO:0031224//intrinsic component of membrane - GO:0016337//single organismal cell-cell adhesion gi|148678210|gb|EDL10157.1|/0/protocadherin beta 14 [Mus musculus] 14043 2875 22.16 24.79666667 0.162188316 Up 0.339849186 Ext2 exostoses (multiple) 2 K02367|1|0.0|1461|mmu:14043|glucuronyl/N-acetylglucosaminyl transferase EXT2 [EC:2.4.1.224 2.4.1.225] GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane GO:0015020//glucuronosyltransferase activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0008375//acetylglucosaminyltransferase activity GO:0048869//cellular developmental process;GO:0000271//polysaccharide biosynthetic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0006023;GO:0001704//formation of primary germ layer gi|74213823|dbj|BAE29346.1|/0/unnamed protein product [Mus musculus] 240057 4023 1.056666667 0.646666667 -0.708426188 Down 0.339773967 Syngap1 synaptic Ras GTPase activating protein 1 homolog (rat) K17631|1|0.0|2210|mmu:240057|Ras/Rap GTPase-activating protein SynGAP GO:0030425//dendrite GO:0019904//protein domain specific binding;GO:0008289//lipid binding GO:0007409//axonogenesis;GO:0048168//regulation of neuronal synaptic plasticity;GO:0072657//protein localization to membrane;GO:0007632//visual behavior;GO:0006915//apoptotic process;GO:0007264//small GTPase mediated signal transduction;GO:0000165//MAPK cascade;GO:0009966//regulation of signal transduction gi|527498272|ref|NP_001268420.1|/0/ras/Rap GTPase-activating protein SynGAP [Mus musculus] 107932 6438 38.81333333 34.91 -0.152911982 Down 0.339736357 Chd4 chromodomain helicase DNA binding protein 4 K11643|1|0.0|2860|mmu:107932|chromodomain-helicase-DNA-binding protein 4 [EC:3.6.4.12] GO:0005815//microtubule organizing center;GO:0000118//histone deacetylase complex GO:0017111//nucleoside-triphosphatase activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding "GO:0006351//transcription, DNA-templated" gi|39204553|ref|NP_666091.1|/0/chromodomain-helicase-DNA-binding protein 4 [Mus musculus] 67488 2840 89.23 98.14 0.137312431 Up 0.339736357 Calcoco1 calcium binding and coiled coil domain 1 K16072|1|1e-12|78.6|tru:101063319|ELKS/RAB6-interacting/CAST family member 1;K10352|2|1e-11|74.7|cbr:CBG23416|myosin heavy chain;K04559|3|3e-11|73.6|clv:102084913|huntingtin interacting protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0000975//regulatory region DNA binding;GO:0019904//protein domain specific binding;GO:0003713//transcription coactivator activity GO:0030522//intracellular receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter gi|60360416|dbj|BAD90452.1|/0/mKIAA1536 protein [Mus musculus] 215999 2872 12.07333333 10.60666667 -0.186852711 Down 0.339604724 Mcu mitochondrial calcium uniporter - - - - - 171171 1849 4.726666667 3.913333333 -0.272425124 Down 0.339548309 Ntng2 netrin G2 K16359|1|0.0|1214|mmu:171171|netrin-G2 GO:0031225//anchored component of membrane;GO:0031225//anchored component of membrane;GO:0031225//anchored component of membrane - GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0048667//cell morphogenesis involved in neuron differentiation gi|19424140|ref|NP_598007.1|/0/netrin-G2 isoform a precursor [Mus musculus] 67732 941 14.59333333 12.89666667 -0.178311226 Down 0.339529505 Iah1 isoamyl acetate-hydrolyzing esterase 1 homolog - - - - - 26940 1596.89 86.08666667 94.79333333 0.138995794 Up 0.339520102 Ecsit ECSIT signalling integrator K04405|1|0.0|859|mmu:26940|evolutionarily conserved signaling intermediate in Toll pathway - - - - 17681 1717 1.953333333 1.433333333 -0.446564005 Down 0.3395107 Msc musculin K09072|1|7e-77|290|mmu:17681|musculin (activated B-cell factor-1) GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity "GO:0007519//skeletal muscle tissue development;GO:0006351//transcription, DNA-templated" gi|6754740|ref|NP_034957.1|/5.76218e-76/musculin [Mus musculus] 23789 1860 34.75666667 38.63 0.15243195 Up 0.339416676 Coro1b "coronin, actin binding protein 1B" K13886|1|0.0|986|mmu:23789|coronin-1B/1C/6 - - - gi|6753494|ref|NP_035908.1|/0/coronin-1B [Mus musculus] 14962 2767 2.55 3.206666667 0.330577146 Up 0.339379067 Cfb complement factor B K01335|1|0.0|1445|rno:294257|component factor B [EC:3.4.21.47] GO:0044421;GO:0044421 GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0002237//response to molecule of bacterial origin;GO:0006952//defense response;GO:0006956//complement activation;GO:0002237//response to molecule of bacterial origin;GO:0006952//defense response;GO:0006956//complement activation gi|218156289|ref|NP_032224.2|/0/complement factor B isoform 1 precursor [Mus musculus] 224640 2603 16.59666667 18.62666667 0.166476005 Up 0.339369664 Lemd2 LEM domain containing 2 K19410|1|1e-49|201|ccw:104698464|inner nuclear membrane protein Man1 GO:0031229 - GO:0007519//skeletal muscle tissue development;GO:0000165//MAPK cascade gi|165972321|ref|NP_666187.2|/0/LEM domain-containing protein 2 [Mus musculus] 67860 1091 35.80333333 39.66666667 0.147833257 Up 0.339341457 S100a16 S100 calcium binding protein A16 K17274|1|1e-05|53.5|ola:101155699|calpactin-1 light chain GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0031981//nuclear lumen GO:0042802//identical protein binding;GO:0046872//metal ion binding GO:0010038//response to metal ion gi|675743219|ref|XP_008982681.1|/1.67848e-50/PREDICTED: protein S100-A16 isoform X1 [Callithrix jacchus] 233328 7467 3.026666667 2.383333333 -0.344749056 Down 0.339219226 Lrrk1 leucine-rich repeat kinase 1 K08843|1|0.0|3818|mmu:233328|leucine-rich repeat kinase 1 [EC:2.7.11.1] GO:0044424 GO:0043169//cation binding;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0032550 GO:0035556//intracellular signal transduction;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|56699427|ref|NP_666303.3|/0/leucine-rich repeat serine/threonine-protein kinase 1 [Mus musculus] 20667 4436 6.193333333 5.256666667 -0.236567842 Down 0.339087593 Sox12 SRY (sex determining region Y)-box 12 K09268|1|8e-59|225|oas:105606202|transcription factor SOX4/11/12 (SOX group C) - - - - 73902 4247 0.6 1 0.736965594 Up 0.339049983 Psmb11 "proteasome (prosome, macropain) subunit, beta type, 11" K11598|1|8e-171|604|mmu:73902|20S proteasome subunit beta 11 [EC:3.4.25.1] - - - - 17537 1787 3.146666667 3.87 0.298509208 Up 0.338974764 Meis3 Meis homeobox 3 K16671|1|0.0|694|mmu:17537|homeobox protein Meis3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006915//apoptotic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0006366//transcription from RNA polymerase II promoter gi|116642900|ref|NP_032653.2|/0/homeobox protein Meis3 isoform a [Mus musculus] 140629 3753 3.146666667 3.866666667 0.297266041 Up 0.338974764 Ubox5 U box domain containing 5 K10600|1|0.0|1032|mmu:140629|U-box domain-containing protein 5 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0046914//transition metal ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0046914//transition metal ion binding;GO:0004842//ubiquitin-protein transferase activity GO:0016567//protein ubiquitination;GO:0016567//protein ubiquitination;GO:0016567//protein ubiquitination gi|74192308|dbj|BAE34338.1|/0/unnamed protein product [Mus musculus] 107971 2135 2.883333333 3.583333333 0.313564622 Up 0.33891835 Frs3 fibroblast growth factor receptor substrate 3 K12461|1|3e-148|528|lcm:102354082|fibroblast growth factor receptor substrate 2 GO:0016020//membrane GO:0070851//growth factor receptor binding GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway "gi|148691633|gb|EDL23580.1|/0/fibroblast growth factor receptor substrate 3, partial [Mus musculus]" 268390 3698.3 8.773333333 10.06333333 0.197911268 Up 0.338908947 Ahsa2 "AHA1, activator of heat shock protein ATPase 2" K11853|1|8e-111|404|mmu:17847|ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12] - - - - 22226 644 0.646666667 1.053333333 0.703867906 Up 0.338890143 Ucn urocortin - GO:0033267;GO:0043025//neuronal cell body GO:0004857//enzyme inhibitor activity;GO:0051429 "GO:0001662//behavioral fear response;GO:0006915//apoptotic process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0007631//feeding behavior;GO:0032147//activation of protein kinase activity;GO:0042311//vasodilation;GO:0016049//cell growth;GO:0008217//regulation of blood pressure;GO:0035249//synaptic transmission, glutamatergic;GO:0031960//response to corticosteroid;GO:0032096//negative regulation of response to food;GO:0007589//body fluid secretion;GO:0035482//gastric motility;GO:0045333//cellular respiration;GO:0051458//corticotropin secretion;GO:0034767//positive regulation of ion transmembrane transport;GO:0045989//positive regulation of striated muscle contraction;GO:0007612//learning;GO:0001819//positive regulation of cytokine production;GO:0001696//gastric acid secretion;GO:0016575//histone deacetylation;GO:0070265//necrotic cell death;GO:0008361//regulation of cell size;GO:0043627//response to estrogen;GO:0006260//DNA replication;GO:0043114//regulation of vascular permeability;GO:0044703;GO:0060548//negative regulation of cell death;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006412//translation;GO:0006171//cAMP biosynthetic process;GO:0030030//cell projection organization" gi|625185297|ref|XP_003497097.2|/1.8891e-44/PREDICTED: urocortin [Cricetulus griseus] 107770 1440 0.656666667 1.066666667 0.699876275 Up 0.338890143 Tm6sf2 transmembrane 6 superfamily member 2 K06853|1|9e-114|412|apla:101804041|hyaluronan and proteoglycan link protein 4 - - - "gi|148696830|gb|EDL28777.1|/0/transmembrane 6 superfamily member 2, isoform CRA_a, partial [Mus musculus]" 75454 583 77.42333333 85.58 0.144505257 Up 0.338786716 Phpt1 phosphohistidine phosphatase 1 K01112|1|4e-70|265|mmu:75454|phosphohistidine phosphatase [EC:3.1.3.-] GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0016791//phosphatase activity;GO:0005246//calcium channel regulator activity GO:0040017//positive regulation of locomotion;GO:0050852//T cell receptor signaling pathway;GO:0051348//negative regulation of transferase activity;GO:0006470//protein dephosphorylation;GO:0031532//actin cytoskeleton reorganization;GO:0032024//positive regulation of insulin secretion gi|58037409|ref|NP_083569.1|/2.87433e-69/14 kDa phosphohistidine phosphatase [Mus musculus] 19400 1620 8.636666667 7.466666667 -0.210010283 Down 0.338692692 Rapsn receptor-associated protein of the synapse K15839|1|2e-10|70.1|cmk:103183050|G-protein signaling modulator 1;K15837|2|4e-10|68.9|lgi:LOTGIDRAFT_132806|G-protein signaling modulator 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0097060//synaptic membrane GO:0046914//transition metal ion binding;GO:0035254//glutamate receptor binding GO:0043065//positive regulation of apoptotic process;GO:0007268//chemical synaptic transmission gi|224967081|ref|NP_033049.2|/0/43 kDa receptor-associated protein of the synapse [Mus musculus] 67106 660 8.706666667 7.536666667 -0.208193905 Down 0.338692692 Zbtb8os zinc finger and BTB domain containing 8 opposite strand - - - - gi|63100438|gb|AAH94629.1|/8.59909e-96/Zbtb8os protein [Mus musculus] 73739 1119 15.59666667 17.59333333 0.173791122 Up 0.338673888 Cby1 chibby homolog 1 (Drosophila) - GO:0005815//microtubule organizing center;GO:0016604//nuclear body GO:0005515//protein binding "GO:0033036;GO:0006351//transcription, DNA-templated;GO:0030178//negative regulation of Wnt signaling pathway;GO:0035051//cardiocyte differentiation;GO:0010927" gi|589932854|ref|XP_006979218.1|/1.1692e-54/PREDICTED: protein chibby homolog 1 [Peromyscus maniculatus bairdii] 16403 5973.63 7.626666667 6.556666667 -0.218090094 Down 0.33852345 Itga6 integrin alpha 6 K06485|1|0.0|2107|rno:114517|integrin alpha 6 - - - "gi|29165793|gb|AAH49132.1|/0/Itga6 protein, partial [Mus musculus]" 217980 5915.83 7.61 6.543333333 -0.217870687 Down 0.33852345 Larp4b "La ribonucleoprotein domain family, member 4B" K18763|1|0.0|1383|mmu:217980|la-related protein 4 - - - gi|50510417|dbj|BAD32194.1|/0/mKIAA0217 protein [Mus musculus] 17714 4065 6.713333333 5.716666667 -0.231855107 Down 0.338429426 Grpel2 "GrpE-like 2, mitochondrial" K03687|1|2e-124|449|mmu:17714|molecular chaperone GrpE GO:0019866//organelle inner membrane;GO:0044429 GO:0042802//identical protein binding GO:0044267//cellular protein metabolic process "gi|29789124|ref|NP_067271.1|/2.06355e-123/grpE protein homolog 2, mitochondrial precursor [Mus musculus]" 434179 3166 17.45333333 15.46 -0.174962277 Down 0.338420023 Gm5595 zinc finger protein 975 K09228|1|0.0|1156|mmu:434179|KRAB domain-containing zinc finger protein - - - "gi|148680477|gb|EDL12424.1|/0/mCG140430, isoform CRA_b, partial [Mus musculus]" 16885 3263.81 5.073333333 4.243333333 -0.25773594 Down 0.338316597 Limk1 "LIM-domain containing, protein kinase" K05743|1|0.0|758|mmu:16885|LIM domain kinase 1 [EC:2.7.11.1] GO:0031981//nuclear lumen;GO:0030426//growth cone;GO:0005924//cell-substrate adherens junction;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0030426//growth cone;GO:0005924//cell-substrate adherens junction;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0032550;GO:0004672//protein kinase activity;GO:0046983//protein dimerization activity;GO:0046914//transition metal ion binding;GO:0032550;GO:0004672//protein kinase activity;GO:0046983//protein dimerization activity GO:0048731//system development;GO:0030307//positive regulation of cell growth;GO:0007265//Ras protein signal transduction;GO:0051017//actin filament bundle assembly;GO:0006796//phosphate-containing compound metabolic process;GO:0006935//chemotaxis;GO:0031397//negative regulation of protein ubiquitination;GO:0030307//positive regulation of cell growth;GO:0051017//actin filament bundle assembly;GO:0006796//phosphate-containing compound metabolic process;GO:0031397//negative regulation of protein ubiquitination gi|6754548|ref|NP_034847.1|/0/LIM domain kinase 1 isoform 1 [Mus musculus] 12238 881 78.48333333 86.27 0.136472639 Up 0.338316597 Commd3 COMM domain containing 3 K11459|1|2e-88|327|mcc:677699|polycomb group RING finger protein 4 - - - gi|22296603|ref|NP_680087.1|/5.20906e-99/COMM domain-containing protein 3 [Mus musculus] 16414 2862 3.663333333 4.436666667 0.276319185 Up 0.338297792 Itgb2 integrin beta 2 K06464|1|0.0|1511|mmu:16414|integrin beta 2 GO:0005887//integral component of plasma membrane GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0019900//kinase binding GO:0001525//angiogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0022604//regulation of cell morphogenesis;GO:0007599//hemostasis;GO:0012501//programmed cell death;GO:0016337//single organismal cell-cell adhesion;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006809//nitric oxide biosynthetic process;GO:0001932//regulation of protein phosphorylation;GO:0031589//cell-substrate adhesion;GO:0006954//inflammatory response;GO:0002682//regulation of immune system process;GO:0030595//leukocyte chemotaxis;GO:0042098//T cell proliferation gi|111607447|ref|NP_032430.2|/0/integrin beta-2 precursor [Mus musculus] 66365 1610.3 14.38 12.72333333 -0.17658699 Down 0.338269585 Ccdc90b coiled-coil domain containing 90B - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - "gi|251823850|ref|NP_001156390.1|/2.25141e-113/coiled-coil domain-containing protein 90B, mitochondrial isoform 2 [Mus musculus]" 236920 4983 13.95666667 12.29333333 -0.183078262 Down 0.338269585 Stard8 START domain containing 8 K10360|1|2e-14|85.1|dre:100332329|myosin IX;K20122|2|4e-14|84.0|myb:102245709|Rho GTPase-activating protein 4 GO:0044464 GO:0008047//enzyme activator activity GO:0007154//cell communication gi|569010072|ref|XP_006528062.1|/0/PREDICTED: stAR-related lipid transfer protein 8 isoform X3 [Mus musculus] 67529 2828 21.26666667 23.79333333 0.161963477 Up 0.338203768 Fgfr1op2 FGFR1 oncogene partner 2 K12656|1|5e-47|192|mdo:100009936|suppressor of IKK-epsilon GO:0044444//cytoplasmic part GO:0042802//identical protein binding GO:0009611//response to wounding gi|13385724|ref|NP_080494.1|/4.54278e-135/FGFR1 oncogene partner 2 homolog [Mus musculus] 243931 5002 1.37 0.92 -0.574470127 Down 0.338194366 Tshz3 teashirt zinc finger family member 3 K09236|1|0.0|1781|mmu:243931|teashirt GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0050879//multicellular organismal movement;GO:0014849;GO:0001822//kidney development;GO:0060537//muscle tissue development;GO:0043009//chordate embryonic development;GO:0050954//sensory perception of mechanical stimulus;GO:0030323//respiratory tube development;GO:0051145//smooth muscle cell differentiation" gi|568945727|ref|XP_006540025.1|/0/PREDICTED: teashirt homolog 3 isoform X2 [Mus musculus] 63986 983 1.776666667 2.336666667 0.395278911 Up 0.338072135 Gmfg "glia maturation factor, gamma" K20368|1|4e-37|157|aam:106494587|protein cornichon;K08870|2|4e-06|54.3|mze:105940779|twinfilin GO:0044464;GO:0044464;GO:0044464 GO:0008092//cytoskeletal protein binding;GO:0005102//receptor binding;GO:0030234//enzyme regulator activity;GO:0008092//cytoskeletal protein binding;GO:0005102//receptor binding;GO:0030234//enzyme regulator activity;GO:0008092//cytoskeletal protein binding;GO:0005102//receptor binding;GO:0019887//protein kinase regulator activity GO:0016310//phosphorylation;GO:0016310//phosphorylation;GO:0001933//negative regulation of protein phosphorylation;GO:0044093 "gi|52696123|pdb|1VKK|A/2.16827e-75/Chain A, Crystal Structure Of Glia Maturation Factor-Gamma (Gmfg) From Mus Musculus At 1.50 A Resolution" 214254 2592 1.94 2.52 0.377367081 Up 0.338043928 Nudt15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 K03574|1|5e-88|328|mmu:214254|8-oxo-dGTP diphosphatase [EC:3.6.1.55] - GO:0043169//cation binding;GO:0047429//nucleoside-triphosphate diphosphatase activity GO:0009154//purine ribonucleotide catabolic process;GO:0009155;GO:0009146 gi|27369730|ref|NP_766115.1|/4.1689e-87/probable 8-oxo-dGTP diphosphatase NUDT15 [Mus musculus] 245683 2626 2.483333333 1.906666667 -0.381225279 Down 0.338043928 Klhl34 kelch-like 34 K10469|1|0.0|1135|mmu:245683|kelch-like protein 34 - - - gi|126157475|ref|NP_001075136.1|/0/kelch-like protein 34 [Mus musculus] 80891 1991 1.93 2.513333333 0.381001175 Up 0.338043928 Fcrls "Fc receptor-like S, scavenger receptor" K06727|1|0.0|997|mmu:80891|Fc receptor-like protein - - - "gi|148747158|ref|NP_109632.2|/0/Fc receptor-like S, scavenger receptor precursor [Mus musculus]" 18813 2432 33.98666667 37.64 0.147297755 Up 0.338025123 Pa2g4 proliferation-associated 2G4 K14813|1|2e-93|346|smm:Smp_150690.1|metalloprotease ARX1 [EC:3.-.-.-];K01265|2|8e-19|98.6|xla:443662|methionyl aminopeptidase [EC:3.4.11.18] GO:0032991//macromolecular complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0003824//catalytic activity "GO:0006412//translation;GO:0022402//cell cycle process;GO:0042254//ribosome biogenesis;GO:0006351//transcription, DNA-templated" gi|6755100|ref|NP_035249.1|/0/proliferation-associated protein 2G4 [Mus musculus] 19729 1031 21.11 23.63333333 0.162896548 Up 0.337959306 Slc50a1 "solute carrier family 50 (sugar transporter), member 1" K15382|1|1e-110|401|mmu:19729|solute carrier family 50 (sugar transporter) GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0022891//substrate-specific transmembrane transporter activity;GO:0005488//binding GO:0006259//DNA metabolic process;GO:1901656;GO:0010628//positive regulation of gene expression gi|188497726|ref|NP_033083.2|/1.11938e-109/sugar transporter SWEET1 [Mus musculus] 329934 2528 0.68 1.093333333 0.685126663 Up 0.337931099 Foxo6 forkhead box O6 K17847|1|2e-171|605|mmu:329934|forkhead box protein O6 - - - gi|55777484|gb|AAH86628.1|/0/Foxo6 protein [Mus musculus] 19184 1277 75.62333333 83.17 0.13723179 Up 0.337902892 Psmc5 "protease (prosome, macropain) 26S subunit, ATPase 5" K03066|1|0.0|738|cge:100771099|26S proteasome regulatory subunit T6 GO:0031981//nuclear lumen;GO:0031982//vesicle;GO:0000502//proteasome complex;GO:0044444//cytoplasmic part "GO:0008134//transcription factor binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0001664//G-protein coupled receptor binding" "GO:0006915//apoptotic process;GO:0044764;GO:0006520//cellular amino acid metabolic process;GO:0006351//transcription, DNA-templated;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0044772//mitotic cell cycle phase transition;GO:0009154//purine ribonucleotide catabolic process;GO:0051320;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle" "gi|149054556|gb|EDM06373.1|/0/peptidase (prosome, macropain) 26S subunit, ATPase 5, isoform CRA_b [Rattus norvegicus]" 53356 1068 71.39666667 78.93333333 0.144777955 Up 0.337902892 Eif3g "eukaryotic translation initiation factor 3, subunit G" K03248|1|2e-174|613|mmu:53356|translation initiation factor 3 subunit G GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0008135//translation factor activity, RNA binding;GO:0036094//small molecule binding" GO:0006412//translation gi|31980808|ref|NP_058572.2|/1.51667e-173/eukaryotic translation initiation factor 3 subunit G [Mus musculus] 11821 866 12.70666667 14.35333333 0.1758002 Up 0.337884087 Aprt adenine phosphoribosyl transferase K00759|1|1e-96|355|mmu:11821|adenine phosphoribosyltransferase [EC:2.4.2.7] GO:0031981//nuclear lumen "GO:0032550;GO:0002060//purine nucleobase binding;GO:0016763//transferase activity, transferring pentosyl groups" GO:0032868//response to insulin;GO:0007589//body fluid secretion;GO:0043096;GO:0006167//AMP biosynthetic process;GO:0044708//single-organism behavior gi|118601013|ref|NP_033828.2|/8.89438e-96/adenine phosphoribosyltransferase [Mus musculus] 16185 2712 0.183333333 0.483333333 1.398549376 Up 0.337846478 Il2rb "interleukin 2 receptor, beta chain" K05069|1|0.0|1053|mmu:16185|interleukin 2 receptor beta GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0004896//cytokine receptor activity;GO:0019838//growth factor binding GO:0046649//lymphocyte activation;GO:0019221//cytokine-mediated signaling pathway;GO:0006915//apoptotic process gi|6680427|ref|NP_032394.1|/0/interleukin-2 receptor subunit beta precursor [Mus musculus] 73828 2097 6.533333333 7.59 0.216280637 Up 0.337808868 Dcaf4 DDB1 and CUL4 associated factor 4 K11799|1|0.0|1015|mmu:73828|WD repeat-containing protein 21A GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex - - gi|259155342|ref|NP_001158728.1|/0/DDB1- and CUL4-associated factor 4 isoform 1 [Mus musculus] 235044 2669 1.986666667 2.573333333 0.373288517 Up 0.337799466 Plppr2 phospholipid phosphatase related 2 K19581|1|0.0|600|bacu:103004178|lipid phosphate phosphatase-related protein type 1/2/5 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0016791//phosphatase activity;GO:0016791//phosphatase activity - gi|594630898|ref|XP_007168990.1|/0/PREDICTED: lipid phosphate phosphatase-related protein type 2-like isoform X1 [Balaenoptera acutorostrata scammoni] 70495 2376 5.82 6.813333333 0.227341637 Up 0.337667833 Atp6ap2 "ATPase, H+ transporting, lysosomal accessory protein 2" K19514|1|6e-175|617|mmu:70495|renin receptor GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0042995//cell projection GO:0005515//protein binding GO:0032905;GO:0002002//regulation of angiotensin levels in blood;GO:0000165//MAPK cascade gi|21361250|ref|NP_081715.1|/5.26743e-174/renin receptor precursor [Mus musculus] 71766 3465 21.18666667 23.68333333 0.160715525 Up 0.33765843 Raver1 "ribonucleoprotein, PTB-binding 1" "K11219|1|6e-74|282|fch:102058589|non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2];K13219|2|7e-11|72.8|ame:726178|splicing factor, proline- and glutamine-rich;K13214|4|7e-10|69.3|xla:380427|non-POU domain-containing octamer-binding protein" - GO:0097159//organic cyclic compound binding;GO:1901363//heterocyclic compound binding - gi|12836469|dbj|BAB23670.1|/0/unnamed protein product [Mus musculus] 93696 851 32.55666667 36.16333333 0.151574667 Up 0.337592613 Chrac1 chromatin accessibility complex 1 K11656|1|4e-51|203|mmu:93696|chromatin accessibility complex protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0046983//protein dimerization activity;GO:0034061//DNA polymerase activity;GO:0003677//DNA binding - gi|18860511|ref|NP_444298.1|/3.19996e-50/chromatin accessibility complex protein 1 [Mus musculus] 21652 2442.67 15.33 17.29333333 0.173858282 Up 0.337583211 Phf1 PHD finger protein 1 K11467|1|0.0|748|mmu:21652|polycomb-like protein 1 GO:0031519//PcG protein complex;GO:0044427;GO:0031519//PcG protein complex;GO:0044427;GO:0031519//PcG protein complex;GO:0044427 GO:0042393//histone binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0046914//transition metal ion binding GO:0033554//cellular response to stress;GO:0031062//positive regulation of histone methylation;GO:0031061//negative regulation of histone methylation;GO:0033554//cellular response to stress;GO:0031062//positive regulation of histone methylation;GO:0031061//negative regulation of histone methylation;GO:0033554//cellular response to stress;GO:0031062//positive regulation of histone methylation;GO:0031061//negative regulation of histone methylation gi|111185928|ref|NP_033369.2|/0/PHD finger protein 1 isoform 1 [Mus musculus] 71756 4583 0.213333333 0.016666667 -3.678071905 Down 0.337517394 Cpn2 "carboxypeptidase N, polypeptide 2" K13023|1|0.0|1005|mmu:71756|carboxypeptidase N regulatory subunit - - - "gi|148665304|gb|EDK97720.1|/0/carboxypeptidase N, polypeptide 2, partial [Mus musculus]" 55978 802 23.78 21.29 -0.159572765 Down 0.33749859 Ift20 intraflagellar transport 20 K16473|1|1e-64|217|pale:102891339|intraflagellar transport protein 20 GO:0030425//dendrite;GO:0005813//centrosome;GO:0030990//intraciliary transport particle GO:0005488//binding GO:0051640//organelle localization gi|955523670|ref|XP_004433450.2|/1.67706e-64/PREDICTED: LOW QUALITY PROTEIN: intraflagellar transport protein 20 homolog [Ceratotherium simum simum] 71684 1965 2.113333333 2.713333333 0.360545954 Up 0.337479785 Rbm43 RNA binding motif protein 43 - - GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding - gi|21313604|ref|NP_084519.1|/0/RNA-binding protein 43 [Mus musculus] 65221 2345 2.12 2.723333333 0.361309313 Up 0.337479785 Slc15a3 "solute carrier family 15, member 3" "K14638|1|0.0|864|mmu:65221|solute carrier family 15 (peptide/histidine transporter), member 3/4" GO:0005764//lysosome;GO:0016020//membrane - GO:0009057//macromolecule catabolic process;GO:0044763;GO:0015833//peptide transport gi|4580995|gb|AAD24570.1|AF121080_1/0/cAMP inducible 1 protein [Mus musculus] 12304 2610 10.30666667 11.72333333 0.185805016 Up 0.337442175 Pdia4 protein disulfide isomerase associated 4 K09582|1|0.0|1153|mmu:12304|protein disulfide-isomerase A4 [EC:5.3.4.1] GO:0044432;GO:0048770 "GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups;GO:0005488//binding;GO:0015036//disulfide oxidoreductase activity" GO:0044267//cellular protein metabolic process;GO:0019725//cellular homeostasis;GO:0018904 gi|313104203|sp|P08003.3|PDIA4_MOUSE/0/RecName: Full=Protein disulfide-isomerase A4; AltName: Full=Endoplasmic reticulum resident protein 72; Short=ER protein 72; Short=ERp-72; Short=ERp72; Flags: Precursor 100336 2060 9.866666667 11.28666667 0.193984797 Up 0.337442175 Ppp1r8 "protein phosphatase 1, regulatory (inhibitor) subunit 8" K13216|1|1e-171|605|mmu:100336|nuclear inhibitor of protein phosphatase 1 [EC:3.1.4.-] GO:0016604//nuclear body;GO:0030529//intracellular ribonucleoprotein complex;GO:0016604//nuclear body;GO:0030529//intracellular ribonucleoprotein complex GO:0003676//nucleic acid binding;GO:0004864//protein phosphatase inhibitor activity;GO:0004540//ribonuclease activity;GO:0003676//nucleic acid binding;GO:0019888//protein phosphatase regulator activity;GO:0019212//phosphatase inhibitor activity "GO:0006396//RNA processing;GO:0044092//negative regulation of molecular function;GO:0019222//regulation of metabolic process;GO:0044699;GO:0006351//transcription, DNA-templated;GO:0032502//developmental process;GO:0006396//RNA processing;GO:0044092//negative regulation of molecular function;GO:0019222//regulation of metabolic process;GO:0044699;GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|676285859|gb|KFO37676.1|/3.3963e-174/Nuclear inhibitor of protein phosphatase 1 [Fukomys damarensis] 109652 1456.18 10.03666667 11.46 0.191326837 Up 0.337442175 Acy1 aminoacylase 1 K14677|1|0.0|834|mmu:109652|aminoacylase [EC:3.5.1.14] GO:0044424;GO:0044424 "GO:0043169//cation binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0043169//cation binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0009057//macromolecule catabolic process;GO:0019538//protein metabolic process;GO:0019752//carboxylic acid metabolic process;GO:0009057//macromolecule catabolic process;GO:0019538//protein metabolic process;GO:0019752//carboxylic acid metabolic process gi|13384746|ref|NP_079647.1|/0/aminoacylase-1 [Mus musculus] 66401 929 17.76666667 15.82 -0.167423432 Down 0.337310542 Nudt2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 K01518|1|4e-73|276|rno:100910067|bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17] GO:0043231//intracellular membrane-bounded organelle GO:0008796//bis(5'-nucleosyl)-tetraphosphatase activity;GO:0032550 GO:0012502//induction of programmed cell death gi|86198335|ref|NP_079815.2|/3.48497e-72/bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [Mus musculus] 227620 1690 2.896666667 3.583333333 0.306908578 Up 0.33722592 Uap1l1 UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 K00972|1|0.0|900|mmu:227620|UDP-N-acetylglucosamine/UDP-N-acetylgalactosamine diphosphorylase [EC:2.7.7.23 2.7.7.83] - "GO:0016772//transferase activity, transferring phosphorus-containing groups" - gi|26346821|dbj|BAC37059.1|/0/unnamed protein product [Mus musculus] 192986 2393 12.10666667 13.73666667 0.182230261 Up 0.337188311 Cyb5d2 cytochrome b5 domain containing 2 K17278|1|1e-12|77.8|api:100169502|membrane-associated progesterone receptor component - GO:0046906//tetrapyrrole binding GO:0048731//system development gi|167736380|ref|NP_001020097.2|/4.38997e-144/neuferricin precursor [Mus musculus] 216190 2958 15.83666667 17.78 0.166986618 Up 0.337056678 Appl2 "adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2" K20132|1|0.0|1291|mmu:216190|DCC-interacting protein 13-beta GO:0005769//early endosome;GO:0031090//organelle membrane;GO:0000118//histone deacetylase complex GO:0017016//Ras GTPase binding;GO:0008289//lipid binding GO:0007154//cell communication gi|21644587|ref|NP_660255.1|/0/DCC-interacting protein 13-beta [Mus musculus] 101985 1764 6.226666667 7.276666667 0.224817675 Up 0.337037873 Usb1 U6 snRNA biogenesis 1 - GO:0043231//intracellular membrane-bounded organelle "GO:0016788//hydrolase activity, acting on ester bonds" GO:0034472//snRNA 3'-end processing gi|255683453|ref|NP_598715.2|/2.16049e-142/U6 snRNA phosphodiesterase [Mus musculus] 246710 5231 6.536666667 7.59 0.215544756 Up 0.337037873 Rhobtb2 Rho-related BTB domain containing 2 K07868|1|0.0|1291|cge:100770205|Rho-related BTB domain-containing protein 1/2 GO:0044464 GO:0032550 GO:0035556//intracellular signal transduction gi|568987700|ref|XP_006519086.1|/0/PREDICTED: rho-related BTB domain-containing protein 2 isoform X1 [Mus musculus] 338359 2436 23.07 20.61 -0.162673499 Down 0.337019068 Supv3l1 "suppressor of var1, 3-like 1 (S. cerevisiae)" K17675|1|0.0|1497|mmu:338359|ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:3.6.4.13] GO:0005759//mitochondrial matrix;GO:0000177//cytoplasmic exosome (RNase complex) GO:0003724//RNA helicase activity;GO:0032550;GO:0042802//identical protein binding;GO:0003723//RNA binding GO:0000963//mitochondrial RNA processing;GO:2000827//mitochondrial RNA surveillance;GO:0006915//apoptotic process;GO:0016049//cell growth;GO:0006325//chromatin organization;GO:0032392//DNA geometric change "gi|31088872|ref|NP_852088.1|/0/ATP-dependent RNA helicase SUPV3L1, mitochondrial precursor [Mus musculus]" 67011 1905 3.543333333 4.303333333 0.280347404 Up 0.336802813 Mettl6 methyltransferase like 6 K00599|1|2e-162|575|mmu:67011|methyltransferase-like protein 6 [EC:2.1.1.-] - GO:0016741 GO:0008152//metabolic process gi|755548745|ref|XP_011243455.1|/0/PREDICTED: methyltransferase-like protein 6 isoform X2 [Mus musculus] 15900 2855 3.506666667 4.263333333 0.28188156 Up 0.336802813 Irf8 interferon regulatory factor 8 K10155|1|0.0|879|mmu:15900|interferon regulatory factor 8 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0001067;GO:0001071//nucleic acid binding transcription factor activity;GO:0001067 GO:0030097//hemopoiesis;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0032496//response to lipopolysaccharide;GO:0001562//response to protozoan;GO:0001819//positive regulation of cytokine production;GO:0006897//endocytosis;GO:0044126;GO:0006952//defense response;GO:0030097//hemopoiesis;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0032496//response to lipopolysaccharide;GO:0001562//response to protozoan;GO:0001819//positive regulation of cytokine production;GO:0006897//endocytosis;GO:0044126;GO:0006952//defense response gi|6680339|ref|NP_032346.1|/0/interferon regulatory factor 8 [Mus musculus] 21877 1389 1.11 1.583333333 0.512405336 Up 0.336765204 Tk1 thymidine kinase 1 K00857|1|2e-117|400|mmu:21877|thymidine kinase [EC:2.7.1.21] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0032550;GO:0019136//deoxynucleoside kinase activity;GO:0046914//transition metal ion binding;GO:0032550;GO:0019136//deoxynucleoside kinase activity GO:0008655//pyrimidine-containing compound salvage;GO:0046125;GO:0006259//DNA metabolic process;GO:0051384//response to glucocorticoid;GO:0014855;GO:0010038//response to metal ion;GO:0009112;GO:0009991//response to extracellular stimulus;GO:0044767//single-organism developmental process;GO:0051260//protein homooligomerization;GO:0007567//parturition;GO:0009117//nucleotide metabolic process;GO:0008655//pyrimidine-containing compound salvage;GO:0046125;GO:0006259//DNA metabolic process;GO:0051384//response to glucocorticoid;GO:0014855;GO:0010038//response to metal ion;GO:0009112;GO:0009991//response to extracellular stimulus;GO:0044767//single-organism developmental process;GO:0051260//protein homooligomerization;GO:0007567//parturition;GO:0009117//nucleotide metabolic process "gi|226958341|ref|NP_033413.2|/6.36328e-128/thymidine kinase, cytosolic isoform 1 [Mus musculus]" 14120 1294 17.18333333 15.25 -0.172200684 Down 0.336755801 Fbp2 fructose bisphosphatase 2 "K03841|1|0.0|667|mmu:14120|fructose-1,6-bisphosphatase I [EC:3.1.3.11]" - GO:0043169//cation binding;GO:0050308//sugar-phosphatase activity GO:0006006//glucose metabolic process "gi|122937183|ref|NP_032020.2|/0/fructose-1,6-bisphosphatase isozyme 2 [Mus musculus]" 382639 3478 2.253333333 2.866666667 0.347313413 Up 0.336746399 Zbtb42 zinc finger and BTB domain containing 42 K10490|1|3e-50|203|mdo:100012474|zinc finger and BTB domain-containing protein 3 GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0006366//transcription from RNA polymerase II promoter gi|257743328|ref|NP_001093930.1|/0/zinc finger and BTB domain-containing protein 42 [Mus musculus] 17210 3498 65.13 71.95666667 0.14380613 Up 0.336652375 Mcl1 myeloid cell leukemia sequence 1 K02539|1|7e-111|404|mmu:17210|myeloid leukemia cell differntiation protein MCL-1 GO:0044429 GO:0046983//protein dimerization activity;GO:0051400//BH domain binding GO:0051716//cellular response to stimulus;GO:0043066//negative regulation of apoptotic process gi|6678824|ref|NP_032588.1|/6.43691e-110/induced myeloid leukemia cell differentiation protein Mcl-1 homolog [Mus musculus] 70044 2764 5.733333333 6.713333333 0.227655118 Up 0.336595961 Tut1 "terminal uridylyl transferase 1, U6 snRNA-specific" K18709|1|0.0|1442|mmu:70044|speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52] GO:0016604//nuclear body;GO:0005849//mRNA cleavage factor complex GO:0032550;GO:0003729//mRNA binding;GO:0046914//transition metal ion binding;GO:0070569//uridylyltransferase activity;GO:0070566//adenylyltransferase activity;GO:0005515//protein binding GO:0016073//snRNA metabolic process;GO:0031124//mRNA 3'-end processing;GO:0000956//nuclear-transcribed mRNA catabolic process gi|37574078|ref|NP_932110.1|/0/speckle targeted PIP5K1A-regulated poly(A) polymerase [Mus musculus] 240752 7929 6.736666667 5.76 -0.225966104 Down 0.336595961 Pik3c2b "phosphoinositide-3-kinase, class 2, beta polypeptide" K00923|1|0.0|3145|mmu:240752|phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154] - - - gi|258645086|ref|NP_001092746.2|/0/phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [Mus musculus] 69638 1264 5.606666667 6.586666667 0.232405241 Up 0.336595961 Enho energy homeostasis associated - - - - - 217198 3007 10.02666667 11.42333333 0.188141625 Up 0.336520742 Plekhh3 "pleckstrin homology domain containing, family H (with MyTH4 domain) member 3" K12559|1|3e-101|372|dre:566674|myosin X GO:0043232 GO:0008289//lipid binding GO:0007154//cell communication gi|965960509|ref|XP_014954281.1|/0/PREDICTED: LOW QUALITY PROTEIN: pleckstrin homology domain-containing family H member 3 isoform X1 [Ovis aries] 68106 1420.62 15.70333333 17.62 0.166143093 Up 0.336445523 Nt5c3b "5'-nucleotidase, cytosolic IIIB" K01081|1|2e-146|521|mmu:68106|5'-nucleotidase [EC:3.1.3.5] GO:0044424;GO:0044424 GO:0008252//nucleotidase activity;GO:0046872//metal ion binding;GO:0036094//small molecule binding;GO:0008252//nucleotidase activity;GO:0046872//metal ion binding;GO:0036094//small molecule binding GO:0006753//nucleoside phosphate metabolic process;GO:0006753//nucleoside phosphate metabolic process gi|156627551|ref|NP_080837.3|/7.52749e-148/7-methylguanosine phosphate-specific 5'-nucleotidase isoform 2 [Mus musculus] 213603 2589 0.01 0.19 4.247927513 Up 0.336398511 Slc44a3 "solute carrier family 44, member 3" "K15282|1|0.0|1304|mmu:213603|solute carrier family 44 (choline transporter-like protein), member 3" GO:0031224//intrinsic component of membrane - GO:0044763;GO:0046165;GO:0006650//glycerophospholipid metabolic process gi|225579159|ref|NP_663369.2|/0/choline transporter-like protein 3 [Mus musculus] 100503117 645 0.193333333 0.01 -4.273018494 Down 0.336398511 2010010A06Rik RIKEN cDNA 2010010A06 gene - GO:0016021//integral component of membrane GO:0019900//kinase binding;GO:0005003//ephrin receptor activity;GO:0032550 GO:0001952//regulation of cell-matrix adhesion;GO:0001933//negative regulation of protein phosphorylation;GO:0016477//cell migration;GO:0000904//cell morphogenesis involved in differentiation;GO:0008283//cell proliferation;GO:0032233//positive regulation of actin filament bundle assembly;GO:0001525//angiogenesis "gi|239782133|pdb|3HIL|A/1.57228e-23/Chain A, Sam Domain Of Human Ephrin Type-A Receptor 1 (Epha1)" 100504333 1980 0.01 0.19 4.247927513 Up 0.336398511 Gm16712 "predicted gene, 16712" - GO:0044421 GO:0005126//cytokine receptor binding GO:0007166//cell surface receptor signaling pathway "gi|148691745|gb|EDL23692.1|/1.57182e-19/Epstein-Barr virus induced gene 3, isoform CRA_a, partial [Mus musculus]" 664987 631 0.01 0.193333333 4.273018494 Up 0.336398511 Gm14393 predicted gene 14393 K09228|1|8e-113|407|mmu:664987|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - "gi|148233986|ref|NP_001079015.1|/5.93757e-112/novel KRAB box and zinc finger, C2H2 type domain containing protein [Mus musculus]" 78478 299 0.19 0.01 -4.247927513 Down 0.336398511 Tmsb15a thymosin beta 15a "K13785|1|4e-11|68.6|xtr:100497578|thymosin beta 10;K05764|2|1e-10|67.0|amj:102577269|thymosin, beta 4" GO:0005884//actin filament GO:0003779//actin binding GO:0030837//negative regulation of actin filament polymerization;GO:0032232//negative regulation of actin filament bundle assembly "gi|148691888|gb|EDL23835.1|/9.13881e-36/RIKEN cDNA 1700129I15, partial [Mus musculus]" 15490 4574 2.12 1.586666667 -0.418065192 Down 0.336370304 Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 K13373|1|0.0|670|mmu:15490|17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0005126//cytokine receptor binding;GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process gi|87162470|ref|NP_034606.3|/0/3-keto-steroid reductase [Mus musculus] 20815 2484 9.54 8.29 -0.202617165 Down 0.336360901 Srpk1 serine/arginine-rich protein specific kinase 1 K15409|1|0.0|1209|mmu:20815|serine/threonine-protein kinase SRPK1 [EC:2.7.11.1] GO:0034399//nuclear periphery GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding "GO:0006323//DNA packaging;GO:0019079//viral genome replication;GO:0006796//phosphate-containing compound metabolic process;GO:0048869//cellular developmental process;GO:0006464//cellular protein modification process;GO:0000398//mRNA splicing, via spliceosome;GO:0006952//defense response;GO:0035556//intracellular signal transduction" gi|31982726|ref|NP_058075.2|/0/SRSF protein kinase 1 [Mus musculus] 80284 1037 32.22 35.67 0.146754722 Up 0.336323292 Smim12 small integral membrane protein 12 - GO:0031224//intrinsic component of membrane - - gi|685513844|ref|XP_009202763.1|/4.08669e-51/PREDICTED: small integral membrane protein 12 isoform X1 [Papio anubis] 66469 785 66.45666667 73.07666667 0.136996896 Up 0.336257475 Fam213b "family with sequence similarity 213, member B" K15717|1|7e-94|345|mmu:66469|prostamide/prostaglandin F2alpha synthase [EC:1.11.1.20] GO:0044444//cytoplasmic part "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0006693//prostaglandin metabolic process gi|27754130|ref|NP_079858.2|/5.82486e-93/prostamide/prostaglandin F synthase [Mus musculus] 52717 1329 31.68333333 35.11666667 0.148431782 Up 0.336154049 Anapc16 anaphase promoting complex subunit 16 - GO:0000152//nuclear ubiquitin ligase complex - GO:0032446//protein modification by small protein conjugation;GO:0000087//mitotic M phase "gi|148700241|gb|EDL32188.1|/2.259e-42/DNA segment, Chr 10, ERATO Doi 641, expressed, isoform CRA_b [Mus musculus]" 22152 1758 0.196666667 0.493333333 1.326810316 Up 0.336154049 Tubb3 "tubulin, beta 3 class III" K07375|1|0.0|829|lve:103082376|tubulin beta GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0016020//membrane;GO:0015630//microtubule cytoskeleton GO:0005198//structural molecule activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0033218//amide binding GO:0006458//'de novo' protein folding;GO:0006935//chemotaxis;GO:0030154//cell differentiation;GO:0043623//cellular protein complex assembly;GO:0009154//purine ribonucleotide catabolic process;GO:0000087//mitotic M phase gi|532003341|ref|XP_005345916.1|/0/PREDICTED: tubulin beta-3 chain [Microtus ochrogaster] 226040 2462 13.43666667 11.84 -0.182506202 Down 0.336125842 Tmem252 transmembrane protein 252 - GO:0031224//intrinsic component of membrane - - gi|34147189|ref|NP_898983.1|/1.06277e-92/transmembrane protein 252 [Mus musculus] 68857 2857 0.633333333 1.033333333 0.706268797 Up 0.336116439 Dtwd2 DTW domain containing 2 - - - - gi|283837781|ref|NP_001164431.1|/2.02342e-90/DTW domain-containing protein 2 isoform 2 [Mus musculus] 52331 1985 1.8 2.356666667 0.388750808 Up 0.336022415 Stbd1 starch binding domain 1 K14819|1|6e-06|55.5|sko:102807933|dual specificity phosphatase 12 [EC:3.1.3.16 3.1.3.48] GO:0016021//integral component of membrane GO:0030247//polysaccharide binding GO:0003012//muscle system process gi|30424697|ref|NP_780305.1|/1.12281e-150/starch-binding domain-containing protein 1 [Mus musculus] 224617 7359.55 2.433333333 1.866666667 -0.382469637 Down 0.335984806 Tbc1d24 "TBC1 domain family, member 24" K00771|1|3e-15|88.6|myb:102241358|protein xylosyltransferase [EC:2.4.2.26] GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424 - GO:0030030//cell projection organization;GO:0030030//cell projection organization;GO:0030030//cell projection organization;GO:0030030//cell projection organization;GO:0030030//cell projection organization;GO:0030030//cell projection organization;GO:0030030//cell projection organization;GO:0030030//cell projection organization "gi|148690351|gb|EDL22298.1|/0/TBC1 domain family, member 24, isoform CRA_c, partial [Mus musculus]" 67290 857 9.59 8.35 -0.199754618 Down 0.335787356 3110040N11Rik RIKEN cDNA 3110040N11 gene K09131|1|2e-56|221|mmu:67290|uncharacterized protein - - - gi|568948346|ref|XP_006541177.1|/3.21714e-64/PREDICTED: UPF0235 protein C15orf40 homolog isoform X2 [Mus musculus] 71910 1515.99 5.5 6.466666667 0.233590628 Up 0.335749746 Plpp5 phospholipid phosphatase 5 K01080|1|8e-44|180|dme:Dmel_CG12746|phosphatidate phosphatase [EC:3.1.3.4] - - - - 17970 3590 1.503333333 2.023333333 0.428569083 Up 0.335730941 Ncf2 neutrophil cytosolic factor 2 K08010|1|0.0|966|mmu:17970|neutrophil cytosolic factor 2 - - - - 97863 1381 8.28 7.15 -0.211687526 Down 0.335730941 Fam8a1 "family with sequence similarity 8, member A1" - - - - gi|148709081|gb|EDL41027.1|/7.62254e-174/mCG20456 [Mus musculus] 228960 3767.83 8.306666667 7.176666667 -0.210955749 Down 0.335730941 Stx16 syntaxin 16 K08489|1|1e-158|563|mmu:228960|syntaxin 16 - - - gi|156231063|ref|NP_001095895.1|/7.77671e-146/syntaxin-16 isoform d [Mus musculus] 72016 2179 1.483333333 2 0.431157165 Up 0.335730941 1600002H07Rik RIKEN cDNA 1600002H07 gene - - - - gi|58037283|ref|NP_082332.1|/0/uncharacterized protein C16orf59 homolog [Mus musculus] 69786 2133 7.06 8.186666667 0.213607971 Up 0.335730941 Tprkb Tp53rk binding protein K15901|1|5e-91|338|mmu:69786|EKC/KEOPS complex subunit CGI121/TPRKB GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle GO:0019900//kinase binding;GO:0019900//kinase binding - "gi|148666733|gb|EDK99149.1|/5.36266e-112/Tp53rk binding protein, isoform CRA_c [Mus musculus]" 105855 4717 1.7 2.246666667 0.402251344 Up 0.335693332 Nckap1l NCK associated protein 1 like K05750|1|0.0|2242|mmu:105855|NCK-associated protein 1 GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0019887//protein kinase regulator activity "GO:0033627//cell adhesion mediated by integrin;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0006915//apoptotic process;GO:0002260//lymphocyte homeostasis;GO:0050851//antigen receptor-mediated signaling pathway;GO:0043374//CD8-positive, alpha-beta T cell differentiation;GO:0006911//phagocytosis, engulfment;GO:0007163//establishment or maintenance of cell polarity;GO:0001934//positive regulation of protein phosphorylation;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0030888//regulation of B cell proliferation;GO:0042492//gamma-delta T cell differentiation;GO:0030183//B cell differentiation;GO:0030041//actin filament polymerization;GO:0042098//T cell proliferation;GO:0030218//erythrocyte differentiation;GO:0001818//negative regulation of cytokine production;GO:0043367//CD4-positive, alpha-beta T cell differentiation" "gi|148671968|gb|EDL03915.1|/0/NCK associated protein 1 like, isoform CRA_b, partial [Mus musculus]" 317717 3992 2.333333333 2.953333333 0.339951777 Up 0.335589906 Sec22a "SEC22 homolog A, vesicle trafficking protein" K08520|1|1e-176|623|mmu:317717|SEC22 vesicle trafficking protein A/C GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0016482//cytosolic transport;GO:0045184//establishment of protein localization gi|672071042|ref|XP_008766914.1|/0/PREDICTED: vesicle-trafficking protein SEC22a isoform X2 [Rattus norvegicus] 12348 1450 3.46 4.206666667 0.281905467 Up 0.335533491 Car11 carbonic anhydrase 11 K18245|1|4e-33|145|pale:102895979|carbonic anhydrase 2 [EC:4.2.1.1] GO:0044459 - - gi|625290240|ref|XP_007636877.1|/0/PREDICTED: carbonic anhydrase-related protein 11 isoform X4 [Cricetulus griseus] 668415 2200 3.466666667 4.22 0.283693876 Up 0.335533491 Gm9159 predicted gene 9159 - - - - gi|82793879|ref|XP_728215.1|/7.48556e-17/hypothetical protein [Plasmodium yoelii yoelii 17XNL] 72472 3750.89 6.306666667 7.34 0.21890238 Up 0.33541126 Slc16a10 "solute carrier family 16 (monocarboxylic acid transporters), member 10" "K08187|1|1e-149|532|mmu:72472|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 10" GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763;GO:0006865//amino acid transport;GO:0044763 "gi|148672996|gb|EDL04943.1|/0/solute carrier family 16 (monocarboxylic acid transporters), member 10, isoform CRA_b, partial [Mus musculus]" 12988 2777 15.00666667 16.89 0.170565772 Up 0.335392456 Csk c-src tyrosine kinase K05728|1|0.0|915|ngi:103736876|c-src tyrosine kinase [EC:2.7.10.2] GO:0030054//cell junction;GO:0043231//intracellular membrane-bounded organelle;GO:0044425;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part;GO:0030054//cell junction;GO:0043231//intracellular membrane-bounded organelle;GO:0044425;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part GO:0004713//protein tyrosine kinase activity;GO:0019902//phosphatase binding;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0019902//phosphatase binding;GO:0032550 GO:0043405//regulation of MAP kinase activity;GO:0043409//negative regulation of MAPK cascade;GO:0050851//antigen receptor-mediated signaling pathway;GO:0042996//regulation of Golgi to plasma membrane protein transport;GO:0032870//cellular response to hormone stimulus;GO:0032845;GO:0045216//cell-cell junction organization;GO:0007599//hemostasis;GO:0002431//Fc receptor mediated stimulatory signaling pathway;GO:0010985;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0038127//ERBB signaling pathway;GO:0042110//T cell activation;GO:0001818//negative regulation of cytokine production;GO:0006909//phagocytosis;GO:0031294//lymphocyte costimulation;GO:0043405//regulation of MAP kinase activity;GO:0043409//negative regulation of MAPK cascade;GO:0050851//antigen receptor-mediated signaling pathway;GO:0042996//regulation of Golgi to plasma membrane protein transport;GO:0032870//cellular response to hormone stimulus;GO:0032845;GO:0045216//cell-cell junction organization;GO:0007599//hemostasis;GO:0002431//Fc receptor mediated stimulatory signaling pathway;GO:0010985;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0038127//ERBB signaling pathway;GO:0042110//T cell activation;GO:0001818//negative regulation of cytokine production;GO:0006909//phagocytosis;GO:0031294//lymphocyte costimulation "gi|148693971|gb|EDL25918.1|/0/c-src tyrosine kinase, isoform CRA_a, partial [Mus musculus]" 67952 4986 14.63 16.51333333 0.174701598 Up 0.335392456 Tomm20 translocase of outer mitochondrial membrane 20 homolog (yeast) K17770|1|1e-61|241|mmu:67952|mitochondrial import receptor subunit TOM20 GO:0031224//intrinsic component of membrane;GO:0005741//mitochondrial outer membrane GO:0008320//protein transmembrane transporter activity;GO:0005515//protein binding GO:0006605//protein targeting;GO:0019538//protein metabolic process "gi|440901027|gb|ELR52036.1|/8.17988e-61/Mitochondrial import receptor subunit TOM20-like protein, partial [Bos mutus]" 77878 1093 0.846666667 1.273333333 0.588744141 Up 0.335392456 6030440G07Rik RIKEN cDNA 6030440G07 gene "K03847|1|2e-06|38.1|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - - 67350 451 0.473333333 0.846666667 0.838937567 Up 0.335373651 1700084E18Rik RIKEN cDNA 1700084E18 gene - - - - gi|26330127|dbj|BAC28802.1|/2.22623e-18/unnamed protein product [Mus musculus] 94223 4226 3.963333333 3.246666667 -0.287755038 Down 0.335307834 Dgcr8 DiGeorge syndrome critical region gene 8 K18419|1|0.0|1479|mmu:94223|microprocessor complex subunit DGCR8 GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003723//RNA binding GO:0035196//production of miRNAs involved in gene silencing by miRNA gi|41152099|ref|NP_201581.2|/0/microprocessor complex subunit DGCR8 [Mus musculus] 109095 3016 3.936666667 3.213333333 -0.292903913 Down 0.335307834 Rbm15b RNA binding motif protein 15B K13190|1|0.0|1238|mmu:109095|RNA-binding protein 15 - - - "gi|148689224|gb|EDL21171.1|/0/mCG19533, partial [Mus musculus]" 20135 2199 1.413333333 1.923333333 0.444507054 Up 0.335119786 Rrm2 ribonucleotide reductase M2 K10808|1|0.0|755|mmu:20135|ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] GO:0043234//protein complex;GO:0012505//endomembrane system;GO:0044424 GO:0046872//metal ion binding;GO:0016728 GO:0006259//DNA metabolic process;GO:0009165//nucleotide biosynthetic process;GO:0051262//protein tetramerization;GO:0009112;GO:0009132//nucleoside diphosphate metabolic process;GO:0008283//cell proliferation "gi|148705043|gb|EDL36990.1|/0/ribonucleotide reductase M2, partial [Mus musculus]" 19201 3138 9.633333333 11.00666667 0.192270628 Up 0.335091579 Pstpip2 proline-serine-threonine phosphatase-interacting protein 2 K20124|1|0.0|681|mmu:19201|proline-serine-threonine phosphatase interacting protein 2 GO:0044444//cytoplasmic part;GO:0043232 - GO:0006996//organelle organization gi|86355499|ref|NP_038859.3|/0/proline-serine-threonine phosphatase-interacting protein 2 [Mus musculus] 19736 2952 11.23666667 9.87 -0.187092137 Down 0.335091579 Rgs4 regulator of G-protein signaling 4 K16449|1|3e-92|342|mmu:19736|regulator of G-protein signaling - - - gi|829785807|ref|XP_012624111.1|/4.52475e-93/PREDICTED: regulator of G-protein signaling 4 isoform X1 [Microcebus murinus] 100503104 2765 0.713333333 1.123333333 0.655137795 Up 0.335072774 Gm19557 "predicted gene, 19557" - GO:0005856//cytoskeleton;GO:0000783//nuclear telomere cap complex GO:0003697//single-stranded DNA binding GO:0000723//telomere maintenance;GO:0006260//DNA replication gi|569006235|ref|XP_006526661.1|/3.87599e-14/PREDICTED: CST complex subunit STN1 isoform X2 [Mus musculus] 22295 11149.38 1.11 0.703333333 -0.658279178 Down 0.335072774 Cdh23 cadherin 23 (otocadherin) K06813|1|0.0|6239|mmu:22295|cadherin 23 GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005902//microvillus;GO:0031224//intrinsic component of membrane;GO:0032421//stereocilium bundle;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005902//microvillus;GO:0031224//intrinsic component of membrane;GO:0032421//stereocilium bundle;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005902//microvillus;GO:0031224//intrinsic component of membrane;GO:0032421//stereocilium bundle GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0007626//locomotory behavior;GO:0006874//cellular calcium ion homeostasis;GO:0016337//single organismal cell-cell adhesion;GO:0060004//reflex;GO:0050954//sensory perception of mechanical stimulus;GO:0002093//auditory receptor cell morphogenesis;GO:0007601//visual perception;GO:0070838//divalent metal ion transport;GO:0007626//locomotory behavior;GO:0006874//cellular calcium ion homeostasis;GO:0016337//single organismal cell-cell adhesion;GO:0060004//reflex;GO:0050954//sensory perception of mechanical stimulus;GO:0002093//auditory receptor cell morphogenesis;GO:0007601//visual perception;GO:0070838//divalent metal ion transport;GO:0007626//locomotory behavior;GO:0006874//cellular calcium ion homeostasis;GO:0016337//single organismal cell-cell adhesion;GO:0060004//reflex;GO:0050954//sensory perception of mechanical stimulus;GO:0002093//auditory receptor cell morphogenesis;GO:0007601//visual perception;GO:0070838//divalent metal ion transport gi|755534504|ref|XP_011241740.1|/0/PREDICTED: cadherin-23 isoform X1 [Mus musculus] 15277 5524 67.71333333 61.56666667 -0.13729048 Down 0.335063372 Hk2 hexokinase 2 K00844|1|0.0|1834|mmu:15277|hexokinase [EC:2.7.1.1] - - - gi|7305143|ref|NP_038848.1|/0/hexokinase-2 [Mus musculus] 58207 2601 61.05666667 67.2 0.138312404 Up 0.335025763 Slc43a3 "solute carrier family 43, member 3" "K08230|1|0.0|885|mmu:58207|MFS transporter, LAT3 family, solute carrier family 43, member 3" GO:0031224//intrinsic component of membrane - GO:0044763 gi|120587005|ref|NP_067373.2|/0/solute carrier family 43 member 3 [Mus musculus] 664610 759 0.01 0.186666667 4.222392421 Up 0.334978751 Rhox4d reproductive homeobox 4D K09329|1|4e-09|63.9|bta:534258|paired mesoderm homeobox protein;K09452|2|6e-08|60.1|pbi:103064655|homeobox protein aristaless-related;K09331|3|1e-07|59.3|shr:100916463|short stature homeobox protein GO:0043231//intracellular membrane-bounded organelle - - gi|89242162|ref|NP_001034784.1|/3.51284e-116/reproductive homeobox 4D [Mus musculus] 381493 741 0.01 0.186666667 4.222392421 Up 0.334978751 S100a7a S100 calcium binding protein A7A - - GO:0046872//metal ion binding - gi|568923107|ref|XP_006501694.1|/1.32394e-72/PREDICTED: protein S100-A15A isoform X2 [Mus musculus] 20530 1841 11.91 13.47666667 0.17829029 Up 0.334969348 Slc31a2 "solute carrier family 31, member 2" "K14687|1|1e-68|263|mmu:20530|solute carrier family 31 (copper transporter), member 2" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0022890//inorganic cation transmembrane transporter activity;GO:0022890//inorganic cation transmembrane transporter activity GO:0006825//copper ion transport;GO:0006825//copper ion transport gi|13384632|ref|NP_079562.1|/1.08298e-67/probable low affinity copper uptake protein 2 isoform 1 [Mus musculus] 210106 4007.77 5.433333333 4.583333333 -0.245440346 Down 0.334912934 Papd7 PAP associated domain containing 7 K03514|1|0.0|1028|lve:103069908|non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0034061//DNA polymerase activity;GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0034061//DNA polymerase activity GO:0006259//DNA metabolic process;GO:0042221//response to chemical;GO:0000087//mitotic M phase;GO:0006259//DNA metabolic process;GO:0042221//response to chemical;GO:0000087//mitotic M phase gi|568983218|ref|XP_006517248.1|/0/PREDICTED: non-canonical poly(A) RNA polymerase PAPD7 isoform X1 [Mus musculus] 233246 7633 0.203333333 0.5 1.298081353 Up 0.334894129 Ano5 anoctamin 5 K19480|1|0.0|1538|mmu:233246|anoctamin-5 - - - - 108124 2332 60.17 66.21333333 0.138077404 Up 0.33481891 Napa N-ethylmaleimide sensitive fusion protein attachment protein alpha K15296|1|4e-150|534|mmu:108124|alpha-soluble NSF attachment protein GO:0031201//SNARE complex GO:0000149//SNARE binding GO:0007417//central nervous system development;GO:0008105//asymmetric protein localization;GO:0007270//neuron-neuron synaptic transmission;GO:0030154//cell differentiation;GO:0016082//synaptic vesicle priming;GO:0015031//protein transport gi|13385392|ref|NP_080174.1|/3.37751e-149/alpha-soluble NSF attachment protein [Mus musculus] 14677 3193 1.136666667 1.61 0.50225145 Up 0.334668472 Gnai1 "guanine nucleotide binding protein (G protein), alpha inhibiting 1" K04630|1|0.0|712|pale:102885642|guanine nucleotide-binding protein G(i) subunit alpha - - - gi|742157971|ref|XP_010846404.1|/0/PREDICTED: guanine nucleotide-binding protein G(i) subunit alpha-1 isoform X1 [Bison bison bison] 16367 9163 4.06 4.863333333 0.26046575 Up 0.33462146 Irs1 insulin receptor substrate 1 K16172|1|0.0|1994|mmu:16367|insulin receptor substrate 1 GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0044444//cytoplasmic part "GO:0008289//lipid binding;GO:0060089;GO:0005102//receptor binding;GO:0019904//protein domain specific binding;GO:0019901//protein kinase binding;GO:0030674//protein binding, bridging" GO:0006006//glucose metabolic process;GO:0010467//gene expression;GO:0005978//glycogen biosynthetic process;GO:0008284//positive regulation of cell proliferation;GO:0048732//gland development;GO:0070091//glucagon secretion;GO:0046326//positive regulation of glucose import;GO:0033365//protein localization to organelle;GO:0016477//cell migration;GO:0048015//phosphatidylinositol-mediated signaling;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0090273//regulation of somatostatin secretion;GO:0051259//protein oligomerization;GO:0050796//regulation of insulin secretion;GO:0006635//fatty acid beta-oxidation;GO:0014074//response to purine-containing compound;GO:0008286//insulin receptor signaling pathway gi|29825829|ref|NP_034700.2|/0/insulin receptor substrate 1 [Mus musculus] 237052 1124 3.963333333 4.76 0.264247264 Up 0.33462146 Tceal1 transcription elongation factor A (SII)-like 1 - - GO:0005488//binding GO:0006366//transcription from RNA polymerase II promoter gi|564400108|ref|XP_006257356.1|/1.06427e-63/PREDICTED: transcription elongation factor A protein-like 1 isoform X2 [Rattus norvegicus] 13823 4051 2.18 2.78 0.350756748 Up 0.334593253 Epb41l3 erythrocyte membrane protein band 4.1 like 3 K06107|1|0.0|1620|mmu:13823|erythrocyte membrane protein band 4.1 GO:0033267;GO:0030054//cell junction;GO:0043232;GO:0044425 GO:0005515//protein binding GO:0030036//actin cytoskeleton organization "gi|148706401|gb|EDL38348.1|/0/erythrocyte protein band 4.1-like 3, isoform CRA_e, partial [Mus musculus]" 66757 1453 2.176666667 2.776666667 0.351233504 Up 0.334593253 Adat2 "adenosine deaminase, tRNA-specific 2" K15441|1|7e-109|396|mmu:66757|tRNA-specific adenosine deaminase 2 [EC:3.5.4.-] - GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0006399//tRNA metabolic process gi|61098160|ref|NP_080024.3|/5.9726e-108/tRNA-specific adenosine deaminase 2 [Mus musculus] 18777 2447 32.27666667 29.02666667 -0.153112687 Down 0.33458385 Lypla1 lysophospholipase 1 K06128|1|2e-119|432|ocu:100125993|lysophospholipase I [EC:3.1.1.5] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0004620//phospholipase activity;GO:0016790//thiolester hydrolase activity GO:0044238//primary metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0042996//regulation of Golgi to plasma membrane protein transport;GO:0006807//nitrogen compound metabolic process;GO:0032768 gi|6678760|ref|NP_032892.1|/1.90902e-118/acyl-protein thioesterase 1 [Mus musculus] 110821 2603 29.12333333 32.36666667 0.152333305 Up 0.334499229 Pcca "propionyl-Coenzyme A carboxylase, alpha polypeptide" K01965|1|0.0|1422|mmu:110821|propionyl-CoA carboxylase alpha chain [EC:6.4.1.3] - - - - 17174 2752 4.606666667 3.833333333 -0.265123755 Down 0.334471022 Masp1 mannan-binding lectin serine peptidase 1 K03992|1|0.0|1439|mmu:17174|mannan-binding lectin serine protease 1 [EC:3.4.21.-] GO:0044421 GO:0004175//endopeptidase activity;GO:0046872//metal ion binding;GO:0042802//identical protein binding GO:0006952//defense response;GO:0002698;GO:0006956//complement activation gi|148226524|ref|NP_032581.2|/0/mannan-binding lectin serine protease 1 precursor [Mus musculus] 227937 4618.63 61.84 55.95666667 -0.144230295 Down 0.334414608 Pkp4 plakophilin 4 "K05690|1|4e-123|446|amj:102573160|catenin (cadherin-associated protein), delta 1" GO:0005911//cell-cell junction;GO:0005819//spindle;GO:0044459;GO:0044444//cytoplasmic part;GO:0005911//cell-cell junction;GO:0005819//spindle;GO:0044459;GO:0044444//cytoplasmic part - GO:0032467//positive regulation of cytokinesis;GO:0022610;GO:0032467//positive regulation of cytokinesis;GO:0022610 gi|51491821|ref|NP_080637.1|/0/plakophilin-4 isoform 1 [Mus musculus] 53378 2552.28 29.59 32.81666667 0.149319009 Up 0.334414608 Sdcbp syndecan binding protein K17254|1|3e-166|588|mmu:53378|syntenin-1 GO:0048770;GO:0005887//integral component of plasma membrane;GO:0048770;GO:0005887//integral component of plasma membrane GO:0042802//identical protein binding;GO:0005126//cytokine receptor binding;GO:0046983//protein dimerization activity;GO:0001664//G-protein coupled receptor binding;GO:0042802//identical protein binding;GO:0005126//cytokine receptor binding;GO:0046983//protein dimerization activity;GO:0001664//G-protein coupled receptor binding GO:0007264//small GTPase mediated signal transduction;GO:0016310//phosphorylation;GO:0007264//small GTPase mediated signal transduction;GO:0016310//phosphorylation "gi|148673740|gb|EDL05687.1|/1.41171e-180/mCG4375, isoform CRA_a, partial [Mus musculus]" 22278 1795.56 14.83666667 16.67666667 0.168663952 Up 0.334414608 Usf1 upstream transcription factor 1 K09106|1|2e-151|538|mcc:719835|upstream stimulatory factor GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0043566//structure-specific DNA binding;GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0043566//structure-specific DNA binding;GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0043566//structure-specific DNA binding;GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0043566//structure-specific DNA binding;GO:0008134//transcription factor binding;GO:0019900//kinase binding" GO:0009299//mRNA transcription;GO:0032868//response to insulin;GO:0033500//carbohydrate homeostasis;GO:0000430//regulation of transcription from RNA polymerase II promoter by glucose;GO:0019318//hexose metabolic process;GO:0009416//response to light stimulus;GO:0030194//positive regulation of blood coagulation;GO:0009299//mRNA transcription;GO:0032868//response to insulin;GO:0033500//carbohydrate homeostasis;GO:0000430//regulation of transcription from RNA polymerase II promoter by glucose;GO:0019318//hexose metabolic process;GO:0009416//response to light stimulus;GO:0030194//positive regulation of blood coagulation;GO:0009299//mRNA transcription;GO:0032868//response to insulin;GO:0033500//carbohydrate homeostasis;GO:0000430//regulation of transcription from RNA polymerase II promoter by glucose;GO:0019318//hexose metabolic process;GO:0009416//response to light stimulus;GO:0030194//positive regulation of blood coagulation;GO:0009299//mRNA transcription;GO:0032868//response to insulin;GO:0033500//carbohydrate homeostasis;GO:0000430//regulation of transcription from RNA polymerase II promoter by glucose;GO:0019318//hexose metabolic process;GO:0009416//response to light stimulus;GO:0030194//positive regulation of blood coagulation gi|795288364|ref|XP_011922958.1|/1.75917e-150/PREDICTED: upstream stimulatory factor 1 isoform X2 [Cercocebus atys] 14068 1875 0.21 0.51 1.280107919 Up 0.3343864 F7 coagulation factor VII K01320|1|0.0|903|mmu:14068|coagulation factor VII [EC:3.4.21.21] GO:0044421;GO:0043226//organelle GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0046872//metal ion binding GO:0048511//rhythmic process;GO:0050918//positive chemotaxis;GO:0048545//response to steroid hormone;GO:0002687//positive regulation of leukocyte migration;GO:0043434//response to peptide hormone;GO:0007596//blood coagulation;GO:0033273//response to vitamin;GO:0009887//organ morphogenesis;GO:0019538//protein metabolic process gi|225543550|ref|NP_034302.2|/0/coagulation factor VII preproprotein [Mus musculus] 66498 1937 28.81666667 32.03666667 0.152820584 Up 0.334301779 Dda1 DET1 and DDB1 associated 1 K11792|1|5e-35|97.1|ngi:103726903|DET1- and DDB1-associated protein 1 - - - gi|659928089|ref|NP_001281187.1|/2.41386e-38/DET1- and DDB1-associated protein 1 isoform 2 [Mus musculus] 56615 943 29.66333333 32.88 0.148529573 Up 0.334301779 Mgst1 microsomal glutathione S-transferase 1 K00799|1|1e-77|292|mmu:56615|glutathione S-transferase [EC:2.5.1.18] GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0044439 "GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0004601//peroxidase activity;GO:0072341//modified amino acid binding;GO:0042802//identical protein binding" GO:0003006//developmental process involved in reproduction;GO:0006982//response to lipid hydroperoxide;GO:0044710;GO:0006790//sulfur compound metabolic process;GO:0009719;GO:0051260//protein homooligomerization;GO:0002237//response to molecule of bacterial origin gi|568942484|ref|XP_006506481.1|/1.00084e-82/PREDICTED: microsomal glutathione S-transferase 1 isoform X1 [Mus musculus] 114143 996 57.49666667 63.34 0.139638548 Up 0.334282974 Atp6v0b "ATPase, H+ transporting, lysosomal V0 subunit B" K03661|1|2e-103|377|mmu:114143|V-type H+-transporting ATPase 21kDa proteolipid subunit GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0033176//proton-transporting V-type ATPase complex;GO:0031090//organelle membrane GO:0015077//monovalent inorganic cation transmembrane transporter activity "GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient" gi|826307001|ref|XP_012504449.1|/4.91514e-107/PREDICTED: V-type proton ATPase 21 kDa proteolipid subunit [Propithecus coquereli] 67023 879.17 64.20333333 58.37333333 -0.137338748 Down 0.334254767 Use1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) K08507|1|2e-138|493|mmu:67023|unconventional SNARE in the endoplasmic reticulum protein 1 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0045184//establishment of protein localization;GO:0007029//endoplasmic reticulum organization;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0045184//establishment of protein localization;GO:0007029//endoplasmic reticulum organization;GO:0006888//ER to Golgi vesicle-mediated transport gi|224809387|ref|NP_001139252.1|/1.25167e-137/vesicle transport protein USE1 isoform 3 [Mus musculus] 13191 4192.39 64.75333333 58.93666667 -0.135788994 Down 0.334235962 Dctn1 dynactin 1 K04648|1|0.0|2088|mmu:13191|dynactin 1 "GO:0005815//microtubule organizing center;GO:0030286//dynein complex;GO:0005819//spindle;GO:0000775//chromosome, centromeric region;GO:0005815//microtubule organizing center;GO:0030286//dynein complex;GO:0005819//spindle;GO:0000775//chromosome, centromeric region" GO:0003774//motor activity;GO:0003774//motor activity GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763 gi|568940565|ref|XP_006505554.1|/0/PREDICTED: dynactin subunit 1 isoform X7 [Mus musculus] 98396 4675 22.26666667 19.96 -0.157773881 Down 0.33422656 Slc41a1 "solute carrier family 41, member 1" K15122|1|0.0|921|mmu:98396|solute carrier family 41 GO:0031224//intrinsic component of membrane GO:0015075//ion transmembrane transporter activity GO:0006811//ion transport;GO:0044763 gi|33238870|ref|NP_776290.1|/0/solute carrier family 41 member 1 [Mus musculus] 16949 3338 19.57 21.87666667 0.160749176 Up 0.33422656 Loxl1 lysyl oxidase-like 1 K14678|1|0.0|990|mmu:16949|lysyl oxidase-like protein 1 [EC:1.4.3.-] GO:0031012//extracellular matrix "GO:0016638//oxidoreductase activity, acting on the CH-NH2 group of donors;GO:0046914//transition metal ion binding" GO:0044710 gi|34978369|sp|P97873.3|LOXL1_MOUSE/0/RecName: Full=Lysyl oxidase homolog 1; AltName: Full=Lysyl oxidase 2; AltName: Full=Lysyl oxidase-like protein 1; Flags: Precursor 70160 1290 22.06 19.75 -0.159580138 Down 0.33422656 Vps36 vacuolar protein sorting 36 K12190|1|0.0|731|mmu:70160|ESCRT-II complex subunit VPS36 GO:0000323//lytic vacuole;GO:0005768//endosome GO:1901981//phosphatidylinositol phosphate binding;GO:0032182//ubiquitin-like protein binding "GO:0044763;GO:0045184//establishment of protein localization;GO:0044765//single-organism transport;GO:0006351//transcription, DNA-templated" gi|30794416|ref|NP_081614.1|/0/vacuolar protein-sorting-associated protein 36 [Mus musculus] 74919 3082 29.62333333 32.83 0.148280762 Up 0.334207755 Slc35f6 "solute carrier family 35, member F6" K00772|1|1e-20|105|sko:100368038|5'-methylthioadenosine phosphorylase [EC:2.4.2.28];K17252|2|3e-12|77.0|apla:101805140|clusterin GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0031981//nuclear lumen - GO:0010823//negative regulation of mitochondrion organization;GO:0051234//establishment of localization;GO:0008283//cell proliferation gi|188497646|ref|NP_783606.2|/0/solute carrier family 35 member F6 precursor [Mus musculus] 19367 2046 28.75666667 31.94666667 0.151768952 Up 0.3339915 Rad9a RAD9 checkpoint clamp component A K10994|1|0.0|756|mmu:19367|cell cycle checkpoint control protein RAD9A [EC:3.1.11.2] GO:0000794//condensed nuclear chromosome "GO:0019900//kinase binding;GO:0019904//protein domain specific binding;GO:0016895//exodeoxyribonuclease activity, producing 5'-phosphomonoesters" GO:0006259//DNA metabolic process;GO:0010212//response to ionizing radiation;GO:0006915//apoptotic process;GO:0031570//DNA integrity checkpoint;GO:0006974//cellular response to DNA damage stimulus gi|6755282|ref|NP_035367.1|/0/cell cycle checkpoint control protein RAD9A [Mus musculus] 231863 2831 1.706666667 1.223333333 -0.480363747 Down 0.333925684 Fbxl18 F-box and leucine-rich repeat protein 18 K10284|1|0.0|1307|mmu:231863|F-box and leucine-rich repeat protein 18 - - - gi|568938701|ref|XP_006504756.1|/0/PREDICTED: F-box/LRR-repeat protein 18 isoform X1 [Mus musculus] 70226 841 0.3 0.056666667 -2.404390255 Down 0.333822257 Rbm3os "RNA binding motif protein 3, opposite strand" - - - - - 17286 2348 9.383333333 8.173333333 -0.199175943 Down 0.333812855 Meox2 mesenchyme homeobox 2 K09322|1|2e-120|436|mmu:17286|homeobox protein MOX GO:0005634//nucleus GO:0003677//DNA binding GO:0048736;GO:0014706//striated muscle tissue development;GO:0001756//somitogenesis "gi|148704897|gb|EDL36844.1|/1.17826e-125/mesenchyme homeobox 2, partial [Mus musculus]" 17118 4186 9.466666667 8.256666667 -0.197297061 Down 0.333812855 Marcks myristoylated alanine rich protein kinase C substrate K12561|1|3e-30|137|bom:102280729|myristoylated alanine-rich C-kinase substrate - - - - 105445 7799.42 5.836666667 4.946666667 -0.238687992 Down 0.333747038 Dock9 dedicator of cytokinesis 9 K13708|1|1e-16|93.2|mde:101891400|dedicator of cytokinesis protein 1;K05727|2|2e-15|89.4|aam:106492150|dedicator of cytokinesis protein 3 - - - gi|124486664|ref|NP_001074508.1|/0/dedicator of cytokinesis protein 9 isoform 1 [Mus musculus] 17988 2909 31.44333333 28.27 -0.153482284 Down 0.333728233 Ndrg1 N-myc downstream regulated gene 1 K18266|1|0.0|805|mmu:17988|protein NDRG1 GO:0005911//cell-cell junction;GO:0005815//microtubule organizing center;GO:0010008//endosome membrane GO:0050839//cell adhesion molecule binding;GO:0017016//Ras GTPase binding;GO:0015631//tubulin binding GO:0002274;GO:0042770//signal transduction in response to DNA damage;GO:0022011//myelination in peripheral nervous system;GO:0090231//regulation of spindle checkpoint;GO:0001666//response to hypoxia gi|564360297|ref|XP_006241770.1|/0/PREDICTED: protein NDRG1 isoform X1 [Rattus norvegicus] 210172 3375 5.323333333 4.486666667 -0.246685903 Down 0.333709429 Zfp526 zinc finger protein 526 "K05205|1|8e-70|268|fpg:101912657|glutamate receptor, ionotropic kainate 5;K09228|3|2e-58|230|pss:102456868|KRAB domain-containing zinc finger protein" - - - - 382562 1306 1.066666667 1.523333333 0.51412226 Up 0.333653014 Pfn4 "profilin family, member 4" K05759|1|2e-61|238|mmu:382562|profilin GO:0043232 GO:0008092//cytoskeletal protein binding GO:0007010//cytoskeleton organization gi|47058966|ref|NP_082652.1|/1.79607e-60/profilin-4 [Mus musculus] 244219 3451 1.72 2.263333333 0.396040509 Up 0.333624807 Zfp668 zinc finger protein 668 K09228|1|2e-126|456|cge:103163817|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|524920227|ref|XP_005064395.1|/0/PREDICTED: zinc finger protein 668 isoform X1 [Mesocricetus auratus] 76416 992 9.363333333 10.70666667 0.193415268 Up 0.333615405 Znrd1as "zinc ribbon domain containing 1, antisense" - - - - - 13367 5633 11.07333333 9.733333333 -0.186083704 Down 0.333615405 Diaph1 diaphanous related formin 1 K05740|1|0.0|1062|mmu:13367|diaphanous 1 GO:0016020//membrane;GO:0005819//spindle;GO:0001726//ruffle;GO:0016020//membrane;GO:0005819//spindle;GO:0001726//ruffle;GO:0016020//membrane;GO:0005819//spindle;GO:0001726//ruffle GO:0017016//Ras GTPase binding;GO:0017016//Ras GTPase binding;GO:0017016//Ras GTPase binding GO:0022604//regulation of cell morphogenesis;GO:0007017//microtubule-based process;GO:0072698;GO:0008154//actin polymerization or depolymerization;GO:0050954//sensory perception of mechanical stimulus;GO:0030030//cell projection organization;GO:0010522//regulation of calcium ion transport into cytosol;GO:0016477//cell migration;GO:0034776//response to histamine;GO:0022604//regulation of cell morphogenesis;GO:0007017//microtubule-based process;GO:0072698;GO:0008154//actin polymerization or depolymerization;GO:0050954//sensory perception of mechanical stimulus;GO:0030030//cell projection organization;GO:0010522//regulation of calcium ion transport into cytosol;GO:0016477//cell migration;GO:0034776//response to histamine;GO:0022604//regulation of cell morphogenesis;GO:0007017//microtubule-based process;GO:0072698;GO:0008154//actin polymerization or depolymerization;GO:0050954//sensory perception of mechanical stimulus;GO:0030030//cell projection organization;GO:0010522//regulation of calcium ion transport into cytosol;GO:0016477//cell migration;GO:0034776//response to histamine gi|60360498|dbj|BAD90493.1|/0/mKIAA4062 protein [Mus musculus] 66610 3715.83 57.19 62.8 0.135001654 Up 0.3335966 Abi3 "ABI gene family, member 3" K06124|1|3e-152|542|rno:287644|phosphoethanolamine/phosphocholine phosphatase [EC:3.1.3.75] GO:0005622//intracellular "GO:0043169//cation binding;GO:0016791//phosphatase activity;GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0043169//cation binding;GO:0016791//phosphatase activity" GO:0016477//cell migration;GO:0030282//bone mineralization;GO:0030278//regulation of ossification;GO:0030282//bone mineralization;GO:0030278//regulation of ossification gi|157786864|ref|NP_001099303.1|/2.32165e-151/phosphoethanolamine/phosphocholine phosphatase [Rattus norvegicus] 225724 4660 2.443333333 1.883333333 -0.375562331 Down 0.333587198 Mapk4 mitogen-activated protein kinase 4 K06855|1|0.0|1143|mmu:225724|mitogen-activated protein kinase 4/6 [EC:2.7.11.24] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process gi|89337268|ref|NP_766220.2|/0/mitogen-activated protein kinase 4 [Mus musculus] 70650 4286 6.063333333 7.073333333 0.222279113 Up 0.333540186 Zcchc8 "zinc finger, CCHC domain containing 8" K13128|1|0.0|1210|mmu:70650|zinc finger CCHC domain-containing protein 8 GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0006396//RNA processing gi|169808385|ref|NP_081770.3|/0/zinc finger CCHC domain-containing protein 8 [Mus musculus] 12552 5132 0.486666667 0.853333333 0.810175441 Up 0.333455564 Cdh11 cadherin 11 "K06803|1|0.0|1548|mmu:12552|cadherin 11, type 2, OB-cadherin" - - - - 170758 1078 0.796666667 1.213333333 0.606927832 Up 0.33343676 Rac3 RAS-related C3 botulinum substrate 3 K07861|1|2e-100|367|lve:103079514|Ras-related C3 botulinum toxin substrate 3 GO:0043005//neuron projection;GO:0005884//actin filament;GO:0016020//membrane;GO:0044297//cell body;GO:0031252//cell leading edge;GO:0044444//cytoplasmic part GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0007010//cytoskeleton organization;GO:0022607//cellular component assembly;GO:0007264//small GTPase mediated signal transduction;GO:0030030//cell projection organization;GO:0009154//purine ribonucleotide catabolic process;GO:0050905//neuromuscular process gi|918643072|ref|XP_005407284.2|/1.91978e-99/PREDICTED: ras-related C3 botulinum toxin substrate 3 [Chinchilla lanigera] 56317 2751 14.70666667 16.51 0.16686983 Up 0.333314529 Anapc7 anaphase promoting complex subunit 7 K03354|1|0.0|989|mmu:56317|anaphase-promoting complex subunit 7 GO:0000152//nuclear ubiquitin ligase complex GO:0019902//phosphatase binding GO:0000209//protein polyubiquitination;GO:0000087//mitotic M phase gi|564379423|ref|XP_006249427.1|/0/PREDICTED: anaphase-promoting complex subunit 7 isoform X1 [Rattus norvegicus] 71723 3847.11 3.936666667 4.723333333 0.262830794 Up 0.333276919 Dhx34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 K20101|1|0.0|2050|mmu:71723|ATP-dependent RNA helicase DHX34 [EC:3.6.4.13] GO:0044464;GO:0044464;GO:0044464 "GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550" - gi|37359788|dbj|BAC97872.1|/0/mKIAA0134 protein [Mus musculus] 224650 6674.17 21.47 19.21333333 -0.160214356 Down 0.333258114 Anks1 ankyrin repeat and SAM domain containing 1 K18441|1|3e-31|141|aqu:100641148|cytohesin - GO:0005102//receptor binding;GO:0005102//receptor binding;GO:0005102//receptor binding GO:0009966//regulation of signal transduction;GO:0031397//negative regulation of protein ubiquitination;GO:0009966//regulation of signal transduction;GO:0031397//negative regulation of protein ubiquitination;GO:0009966//regulation of signal transduction;GO:0031397//negative regulation of protein ubiquitination gi|553727107|ref|NP_001272969.1|/0/ankyrin repeat and SAM domain-containing protein 1A isoform 1 [Mus musculus] 66073 1275 19.73666667 22 0.156625171 Up 0.333258114 Txndc12 thioredoxin domain containing 12 (endoplasmic reticulum) K05360|1|5e-89|330|mmu:66073|protein-disulfide reductase (glutathione) [EC:1.8.4.2] - "GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor" GO:0044710;GO:0019725//cellular homeostasis gi|71679828|gb|AAI00256.1|/1.2667e-95/Txndc12 protein [Rattus norvegicus] 319924 6649 1.996666667 1.483333333 -0.428750667 Down 0.333248712 Apba1 "amyloid beta (A4) precursor protein binding, family A, member 1" K04531|1|0.0|1538|mmu:319924|amyloid beta A4 precursor protein-binding family A member 1 GO:0032991//macromolecular complex;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane GO:0042277//peptide binding;GO:0043168//anion binding;GO:0019904//protein domain specific binding GO:0048731//system development;GO:0015812//gamma-aminobutyric acid transport;GO:0022610;GO:0007267//cell-cell signaling;GO:0043009//chordate embryonic development;GO:0040007//growth;GO:0006887//exocytosis;GO:0006835//dicarboxylic acid transport;GO:0044708//single-organism behavior;GO:0010467//gene expression;GO:0065003;GO:0015031//protein transport;GO:0010970//transport along microtubule gi|79749980|ref|NP_796008.2|/0/amyloid beta A4 precursor protein-binding family A member 1 [Mus musculus] 104184 2355 11.55 13.08 0.179469689 Up 0.333239309 Blmh bleomycin hydrolase K01372|1|0.0|953|mmu:104184|bleomycin hydrolase [EC:3.4.22.40] GO:0043231//intracellular membrane-bounded organelle GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0042221//response to chemical gi|30519997|ref|NP_848760.1|/0/bleomycin hydrolase [Mus musculus] 70892 7409 1.636666667 1.163333333 -0.492495988 Down 0.333220505 Ttll7 "tubulin tyrosine ligase-like family, member 7" K16583|1|0.0|1058|mmu:70892|tubulin polyglutamylase TTLL7 [EC:6.-.-.-] GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle GO:0016881//acid-amino acid ligase activity;GO:0003824//catalytic activity GO:0048731//system development;GO:0048869//cellular developmental process;GO:0018200//peptidyl-glutamic acid modification;GO:0048731//system development;GO:0048869//cellular developmental process;GO:0018200//peptidyl-glutamic acid modification gi|729042231|ref|NP_001289886.1|/0/tubulin polyglutamylase TTLL7 isoform Ttll7 [Mus musculus] 320435 2888 1.16 1.633333333 0.493694443 Up 0.333220505 Rinl Ras and Rab interactor-like K17638|1|1e-10|71.6|pss:102453172|Ras and Rab interactor 1 GO:0005856//cytoskeleton;GO:0031982//vesicle GO:0008047//enzyme activator activity;GO:0005488//binding;GO:0030695//GTPase regulator activity GO:0019222//regulation of metabolic process;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport gi|568946003|ref|XP_006540160.1|/0/PREDICTED: ras and Rab interactor-like protein isoform X3 [Mus musculus] 106957 3905 2.046666667 2.623333333 0.35812498 Up 0.33316409 Slc39a6 "solute carrier family 39 (metal ion transporter), member 6" "K14712|1|0.0|1183|mmu:106957|solute carrier family 39 (zinc transporter), member 6" GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0030027//lamellipodium GO:0046915//transition metal ion transmembrane transporter activity GO:0071577//zinc II ion transmembrane transport;GO:0072503 gi|156105683|ref|NP_631882.2|/0/zinc transporter ZIP6 precursor [Mus musculus] 63953 2712 2.626666667 2.043333333 -0.362308556 Down 0.33316409 Dusp10 dual specificity phosphatase 10 K20216|1|0.0|796|mmu:63953|dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48] - - - "gi|148681139|gb|EDL13086.1|/0/dual specificity phosphatase 10, partial [Mus musculus]" 105245437 1508 0.066666667 0.32 2.263034406 Up 0.333107676 Gm40893 "predicted gene, 40893" K10591|1|3e-08|62.4|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26];K09228|4|1e-06|57.4|rno:102551340|KRAB domain-containing zinc finger protein - - - "gi|148686988|gb|EDL18935.1|/8.96883e-46/mCG145296, partial [Mus musculus]" 74131 2692.04 0.44 0.8 0.862496476 Up 0.333051262 Sash3 SAM and SH3 domain containing 3 K10356|1|8e-06|55.5|hmg:100211911|myosin I;K04438|2|8e-06|55.5|pxy:105386226|proto-oncogene C-crk - - - - 16649 3726 16.51666667 14.73 -0.165165126 Down 0.332900824 Kpna4 karyopherin (importin) alpha 4 K15043|1|2e-151|539|crg:105330652|importin subunit alpha-2 GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0022892//substrate-specific transporter activity GO:0006606//protein import into nucleus;GO:0007166//cell surface receptor signaling pathway gi|74190898|dbj|BAE28230.1|/0/unnamed protein product [Mus musculus] 72650 1692.4 11.36666667 12.89 0.181443025 Up 0.332882019 2810006K23Rik RIKEN cDNA 2810006K23 gene K03462|1|2e-19|99.8|tsp:Tsp_05934|nicotinamide phosphoribosyltransferase [EC:2.4.2.12];K02835|2|3e-06|56.2|pon:100434825|peptide chain release factor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0008079//translation termination factor activity;GO:0008079//translation termination factor activity GO:0006412//translation;GO:0006412//translation "gi|149063270|gb|EDM13593.1|/4.2026e-71/rCG21417, isoform CRA_a [Rattus norvegicus]" 78388 2810 31.72333333 28.65666667 -0.146673565 Down 0.332740983 Mvp major vault protein K17266|1|0.0|1595|mmu:78388|major vault protein GO:0031988//membrane-bounded vesicle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0044444//cytoplasmic part GO:0019900//kinase binding;GO:0019902//phosphatase binding GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006469//negative regulation of protein kinase activity;GO:0023051//regulation of signaling gi|239052674|ref|NP_542369.2|/0/major vault protein [Mus musculus] 20847 4402 6.92 8.01 0.211030205 Up 0.332693971 Stat2 signal transducer and activator of transcription 2 K11221|1|0.0|1728|mmu:20847|signal transducer and activator of transcription 2 GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0046872//metal ion binding;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated;GO:0007154//cell communication" gi|9910572|ref|NP_064347.1|/0/signal transducer and activator of transcription 2 [Mus musculus] 22592 4010 5.13 4.3 -0.254622166 Down 0.332599947 Ercc5 "excision repair cross-complementing rodent repair deficiency, complementation group 5" K10846|1|0.0|2112|mmu:22592|DNA excision repair protein ERCC-5 GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0004519//endonuclease activity;GO:0042802//identical protein binding;GO:0043566//structure-specific DNA binding "GO:0009411//response to UV;GO:0033683//nucleotide-excision repair, DNA incision;GO:0006915//apoptotic process;GO:0040007//growth;GO:0010259//multicellular organism aging" gi|74215723|dbj|BAE23409.1|/0/unnamed protein product [Mus musculus] 239743 2405 2.173333333 2.766666667 0.348239372 Up 0.332590545 Klhl6 kelch-like 6 K10444|1|0.0|1229|mmu:239743|kelch-like protein 6 - - GO:0050851//antigen receptor-mediated signaling pathway;GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains gi|241982773|ref|NP_899246.2|/0/kelch-like protein 6 [Mus musculus] 72091 763 2.133333333 2.723333333 0.352264173 Up 0.332590545 Snhg7 small nucleolar RNA host gene 7 - - - - "gi|148676382|gb|EDL08329.1|/5.16419e-10/mCG1030139, isoform CRA_b [Mus musculus]" 51798 1138 1045.866667 1146.23 0.132197621 Up 0.332581143 Ech1 "enoyl coenzyme A hydratase 1, peroxisomal" "K12663|1|3e-165|583|mmu:51798|Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase [EC:5.3.3.-]" GO:0042579//microbody GO:0043169//cation binding;GO:0005515//protein binding;GO:0003824//catalytic activity GO:0009062//fatty acid catabolic process "gi|568946157|ref|XP_006540235.1|/9.50172e-169/PREDICTED: delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial isoform X1 [Mus musculus]" 12867 449 1027.94 1121.05 0.125094567 Up 0.332552935 Cox7c cytochrome c oxidase subunit VIIc K02272|1|6e-30|131|mmu:12867|cytochrome c oxidase subunit 7c GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0015002//heme-copper terminal oxidase activity GO:0006818//hydrogen transport;GO:0006811//ion transport;GO:0044710 "gi|148692956|gb|EDL24903.1|/2.45048e-41/mCG14133, partial [Mus musculus]" 70134 907 1.063333333 0.666666667 -0.673556424 Down 0.332383693 2210011C24Rik RIKEN cDNA 2210011C24 gene - - - - gi|603843791|ref|NP_001278221.1|/6.07238e-82/uncharacterized protein LOC70134 [Mus musculus] 93691 1344 2.773333333 3.43 0.306587549 Up 0.33237429 Klf7 Kruppel-like factor 7 (ubiquitous) K09207|1|3e-147|524|ecb:100066360|krueppel-like factor 6/7 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0016358//dendrite development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006935//chemotaxis;GO:0006351//transcription, DNA-templated" gi|545191701|ref|XP_003363357.2|/2.22881e-146/PREDICTED: Krueppel-like factor 7 [Equus caballus] 14085 1597 27.27666667 30.32 0.152602402 Up 0.332336681 Fah fumarylacetoacetate hydrolase K01555|1|0.0|853|mmu:14085|fumarylacetoacetase [EC:3.7.1.2] - "GO:0043169//cation binding;GO:0016823//hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances" GO:0006525//arginine metabolic process;GO:0006558//L-phenylalanine metabolic process;GO:0006570//tyrosine metabolic process gi|240120112|ref|NP_034306.2|/0/fumarylacetoacetase [Mus musculus] 53612 1296 50.23333333 55.42666667 0.141935236 Up 0.332280266 Vti1b vesicle transport through interaction with t-SNAREs 1B K08493|1|2e-101|371|mmu:53612|vesicle transport through interaction with t-SNAREs 1 GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part - GO:0006887//exocytosis;GO:0015031//protein transport "gi|149051548|gb|EDM03721.1|/1.48018e-101/rCG62362, isoform CRA_b [Rattus norvegicus]" 13185 2419 9.093333333 10.40666667 0.194626893 Up 0.332252059 Dscr3 Down syndrome critical region gene 3 K18466|1|7e-09|65.5|cin:100179535|vacuolar protein sorting-associated protein 26 GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle - GO:0044765//single-organism transport gi|6681145|ref|NP_031860.1|/4.58488e-157/Down syndrome critical region protein 3 homolog [Mus musculus] 270035 2115 2.386666667 3.01 0.3347664 Up 0.332233254 Letm2 leucine zipper-EF-hand containing transmembrane protein 2 "K17800|1|7e-92|340|mgp:100542996|LETM1 and EF-hand domain-containing protein 1, mitochondrial" GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - "gi|148700885|gb|EDL32832.1|/0/RIKEN cDNA D030041N04, isoform CRA_b, partial [Mus musculus]" 14123 2650 27.24666667 30.26666667 0.151650054 Up 0.332167438 Fbrs fibrosin - - GO:0005102//receptor binding GO:0008284//positive regulation of cell proliferation gi|568949632|ref|XP_006507410.1|/0/PREDICTED: probable fibrosin-1 isoform X1 [Mus musculus] 107003 2407 0.183333333 0.476666667 1.378511623 Up 0.332158035 A330093E20Rik RIKEN cDNA A330093E20 gene K04943|1|8e-32|141|mmu:140492|potassium intermediate/small conductance calcium-activated channel subfamily N member 2 GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0044297//cell body;GO:0031674//I band;GO:0042383//sarcolemma;GO:0005783//endoplasmic reticulum GO:0015269//calcium-activated potassium channel activity;GO:0042802//identical protein binding;GO:0042805//actinin binding;GO:0046983//protein dimerization activity GO:0034765//regulation of ion transmembrane transport;GO:0048167//regulation of synaptic plasticity;GO:0030001//metal ion transport gi|17978282|ref|NP_536713.1|/6.59899e-31/small conductance calcium-activated potassium channel protein 2 isoform SK2-S [Mus musculus] 20972 1077.02 57.25666667 52.09333333 -0.136344928 Down 0.332129828 Syngr1 synaptogyrin 1 K17783|1|4e-29|133|shr:100917660|mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2];K04403|2|4e-28|130|gfr:102037151|TAK1-binding protein 1 GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle;GO:0008021//synaptic vesicle;GO:0016020//membrane - GO:0048168//regulation of neuronal synaptic plasticity;GO:0048168//regulation of neuronal synaptic plasticity gi|46877048|ref|NP_997591.1|/7.41516e-92/synaptogyrin-1 isoform 1a [Mus musculus] 76786 548 0.576666667 0.263333333 -1.130847479 Down 0.332111023 2510003B16Rik RIKEN cDNA 2510003B16 gene - - - - - 100316682 80 0.263333333 0.576666667 1.130847479 Up 0.332111023 Mir1892 microRNA 1892 - - - - - 230796 4175 50.55 55.69666667 0.139879896 Up 0.332101621 Wdtc1 WD and tetratricopeptide repeats 1 K11807|1|0.0|1331|mmu:230796|WD and tetratricopeptide repeats protein 1 - - - - 229317 2322 20.25666667 18.07 -0.164800285 Down 0.331988792 Eif2a eukaryotic translation initiation factor 2A K15026|1|0.0|1101|mmu:229317|translation initiation factor 2A GO:0043234//protein complex;GO:0044424 "GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, RNA binding" GO:0006412//translation;GO:0006464//cellular protein modification process;GO:0042254//ribosome biogenesis;GO:0006984//ER-nucleus signaling pathway gi|26347343|dbj|BAC37320.1|/0/unnamed protein product [Mus musculus] 235584 3227 26.56333333 29.56 0.154210073 Up 0.33197939 Dusp7 dual specificity phosphatase 7 K04459|1|0.0|728|mmu:235584|dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0005488//binding GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0043405//regulation of MAP kinase activity;GO:0006470//protein dephosphorylation gi|238231443|ref|NP_703189.3|/0/dual specificity protein phosphatase 7 [Mus musculus] 407831 1865 27.69666667 30.7 0.148526299 Up 0.33197939 Tmem204 transmembrane protein 204 - GO:0031224//intrinsic component of membrane;GO:0070161 GO:0005488//binding GO:0042692//muscle cell differentiation;GO:0001944//vasculature development;GO:0009966//regulation of signal transduction gi|47564090|ref|NP_001001183.1|/5.97504e-106/transmembrane protein 204 precursor [Mus musculus] 13857 1829 1.346666667 1.84 0.450312974 Up 0.331847757 Epor erythropoietin receptor K05079|1|0.0|952|mmu:13857|erythropoietin receptor GO:0016021//integral component of membrane GO:0005515//protein binding;GO:0004896//cytokine receptor activity GO:0007417//central nervous system development;GO:0043066//negative regulation of apoptotic process;GO:0003208//cardiac ventricle morphogenesis;GO:0019221//cytokine-mediated signaling pathway;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0001893//maternal placenta development;GO:0001570//vasculogenesis gi|116292186|ref|NP_034279.3|/0/erythropoietin receptor precursor [Mus musculus] 72567 5418.66 8.04 6.956666667 -0.208799307 Down 0.331819549 Bclaf1 BCL2-associated transcription factor 1 K13087|1|0.0|1103|mmu:72567|bcl2 associated transcription factor 1 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0005488//binding;GO:0005488//binding;GO:0005488//binding "GO:0006974//cellular response to DNA damage stimulus;GO:0097193//intrinsic apoptotic signaling pathway;GO:0012502//induction of programmed cell death;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0097193//intrinsic apoptotic signaling pathway;GO:0012502//induction of programmed cell death;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0043068//positive regulation of programmed cell death;GO:0097193//intrinsic apoptotic signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated" "gi|148671484|gb|EDL03431.1|/0/mCG2822, isoform CRA_b, partial [Mus musculus]" 16423 1928 14.36666667 16.11666667 0.16582802 Up 0.331800745 Cd47 "CD47 antigen (Rh-related antigen, integrin-associated signal transducer)" "K06266|1|4e-144|514|mmu:16423|CD47 antigen (Rh-related antigen, integrin-associated signal transducer)" GO:0031988//membrane-bounded vesicle;GO:0016021//integral component of membrane GO:0038023//signaling receptor activity GO:0051707//response to other organism;GO:0016337//single organismal cell-cell adhesion;GO:0006954//inflammatory response;GO:0006909//phagocytosis;GO:0048870//cell motility;GO:0007166//cell surface receptor signaling pathway;GO:0042110//T cell activation;GO:0002252;GO:0008283//cell proliferation gi|6754382|ref|NP_034711.1|/3.72447e-143/leukocyte surface antigen CD47 precursor [Mus musculus] 230259 3676.5 0.966666667 1.403333333 0.537767333 Up 0.331800745 E130308A19Rik RIKEN cDNA E130308A19 gene - - - - gi|24233509|ref|NP_694798.1|/0/uncharacterized protein KIAA1958 homolog isoform 1 [Mus musculus] 18176 4470 10.35333333 9.053333333 -0.19357435 Down 0.331791342 Nras neuroblastoma ras oncogene K07828|1|2e-100|369|nle:100592103|GTPase NRas GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0007010//cytoskeleton organization;GO:0042692//muscle cell differentiation;GO:0009154//purine ribonucleotide catabolic process;GO:0016601//Rac protein signal transduction;GO:0006935//chemotaxis;GO:0007599//hemostasis;GO:0002376//immune system process;GO:0007049//cell cycle;GO:0008283//cell proliferation;GO:0007632//visual behavior;GO:0038127//ERBB signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0048168//regulation of neuronal synaptic plasticity;GO:0006468//protein phosphorylation gi|568922037|ref|XP_006501181.1|/1.3506e-99/PREDICTED: GTPase NRas isoform X2 [Mus musculus] 100038882 756 9.206666667 10.50666667 0.190554215 Up 0.331791342 Isg15 ISG15 ubiquitin-like modifier K12159|1|9e-78|291|mmu:100038882|ubiquitin cross-reactive protein GO:0044424 - GO:0002252;GO:0006464//cellular protein modification process;GO:0051603//proteolysis involved in cellular protein catabolic process gi|226874851|ref|NP_056598.2|/7.09788e-77/ubiquitin-like protein ISG15 precursor [Mus musculus] 26448 1693 0.41 0.763333333 0.896689283 Up 0.331725526 Mok MOK protein kinase K08830|1|0.0|862|mmu:26448|renal tumor antigen [EC:2.7.11.22] GO:0044424 GO:0004674//protein serine/threonine kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|7106391|ref|NP_036103.1|/0/MAPK/MAK/MRK overlapping kinase [Mus musculus] 381534 1517 0.32 0.643333333 1.007494537 Up 0.331697318 Ube2u ubiquitin-conjugating enzyme E2U (putative) K10584|1|4e-169|597|mmu:381534|ubiquitin-conjugating enzyme E2 U [EC:2.3.2.23] - - - gi|311771722|ref|NP_001028945.2|/3.20762e-168/ubiquitin-conjugating enzyme E2 U [Mus musculus] 66277 2294 47.78 52.79 0.143857812 Up 0.331678514 Klf15 Kruppel-like factor 15 K09210|1|0.0|710|mmu:66277|krueppel-like factor 15 GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0008645//hexose transport;GO:0030154//cell differentiation;GO:0071417//cellular response to organonitrogen compound;GO:0006366//transcription from RNA polymerase II promoter gi|568942591|ref|XP_006506534.1|/0/PREDICTED: Krueppel-like factor 15 isoform X1 [Mus musculus] 11518 3940.83 54.67 49.68333333 -0.137987406 Down 0.331593892 Add1 adducin 1 (alpha) K18622|1|0.0|1184|mmu:11518|adducin GO:0016020//membrane;GO:0044327//dendritic spine head;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044327//dendritic spine head;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044327//dendritic spine head;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0044444//cytoplasmic part GO:0005102//receptor binding;GO:0046983//protein dimerization activity;GO:0003779//actin binding;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0005102//receptor binding;GO:0046983//protein dimerization activity;GO:0003779//actin binding;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0005102//receptor binding;GO:0046983//protein dimerization activity;GO:0003779//actin binding;GO:0042802//identical protein binding;GO:0043169//cation binding GO:0001525//angiogenesis;GO:0032989;GO:0040007//growth;GO:0043393//regulation of protein binding;GO:0032526//response to retinoic acid;GO:0043009//chordate embryonic development;GO:0019725//cellular homeostasis;GO:0030099//myeloid cell differentiation;GO:0044765//single-organism transport;GO:0006897//endocytosis;GO:0051693//actin filament capping;GO:0019538//protein metabolic process;GO:0001894//tissue homeostasis;GO:0001525//angiogenesis;GO:0032989;GO:0040007//growth;GO:0043393//regulation of protein binding;GO:0032526//response to retinoic acid;GO:0043009//chordate embryonic development;GO:0019725//cellular homeostasis;GO:0030099//myeloid cell differentiation;GO:0044765//single-organism transport;GO:0006897//endocytosis;GO:0051693//actin filament capping;GO:0019538//protein metabolic process;GO:0001894//tissue homeostasis;GO:0001525//angiogenesis;GO:0032989;GO:0040007//growth;GO:0012501//programmed cell death;GO:0043393//regulation of protein binding;GO:0032526//response to retinoic acid;GO:0043009//chordate embryonic development;GO:0019725//cellular homeostasis;GO:0030099//myeloid cell differentiation;GO:0006897//endocytosis;GO:0051693//actin filament capping;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0019538//protein metabolic process;GO:0001894//tissue homeostasis gi|156255171|ref|NP_001019629.2|/0/alpha-adducin isoform 1 [Mus musculus] 13650 2890.46 15.44 13.69666667 -0.172847923 Down 0.33158449 Rhbdf1 rhomboid 5 homolog 1 K02857|1|8e-07|58.9|pon:100452148|rhomboid-related protein 1/2/3 [EC:3.4.21.105] GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0004175//endopeptidase activity;GO:0005515//protein binding GO:0009306//protein secretion;GO:0010498//proteasomal protein catabolic process;GO:0048870//cell motility;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0009306//protein secretion;GO:0010498//proteasomal protein catabolic process;GO:0048870//cell motility;GO:0007173//epidermal growth factor receptor signaling pathway gi|625221300|ref|XP_007650546.1|/0/PREDICTED: inactive rhomboid protein 1 isoform X1 [Cricetulus griseus] 246293 3163 2.57 3.2 0.316303546 Up 0.331575087 Klhl8 kelch-like 8 K10446|1|0.0|1257|mmu:246293|kelch-like protein 8 - - - gi|26340692|dbj|BAC34008.1|/0/unnamed protein product [Mus musculus] 58175 1778 1.24 0.823333333 -0.59079158 Down 0.331575087 Rgs20 regulator of G-protein signaling 20 K16449|1|5e-128|461|cge:100755874|regulator of G-protein signaling - - - gi|110625669|ref|NP_067349.2|/3.50493e-116/regulator of G-protein signaling 20 isoform 2 [Mus musculus] 18642 2884.64 495.3266667 543.38 0.133581173 Up 0.331499868 Pfkm "phosphofructokinase, muscle" K00850|1|0.0|1537|mmu:18642|6-phosphofructokinase 1 [EC:2.7.1.11] GO:0043234//protein complex;GO:0044459;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044459;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044459;GO:0044444//cytoplasmic part GO:0032550;GO:0008443//phosphofructokinase activity;GO:0043169//cation binding;GO:0043168//anion binding;GO:0048029//monosaccharide binding;GO:0019899//enzyme binding;GO:0032550;GO:0008443//phosphofructokinase activity;GO:0043169//cation binding;GO:0043168//anion binding;GO:0048029//monosaccharide binding;GO:0019899//enzyme binding;GO:0032550;GO:0008443//phosphofructokinase activity;GO:0043169//cation binding;GO:0043168//anion binding;GO:0048029//monosaccharide binding;GO:0019899//enzyme binding GO:0033500//carbohydrate homeostasis;GO:0006007//glucose catabolic process;GO:0016310//phosphorylation;GO:0050796//regulation of insulin secretion;GO:0019725//cellular homeostasis;GO:0051260//protein homooligomerization;GO:0033500//carbohydrate homeostasis;GO:0006007//glucose catabolic process;GO:0016310//phosphorylation;GO:0050796//regulation of insulin secretion;GO:0019725//cellular homeostasis;GO:0051260//protein homooligomerization;GO:0033500//carbohydrate homeostasis;GO:0006007//glucose catabolic process;GO:0016310//phosphorylation;GO:0050796//regulation of insulin secretion;GO:0019725//cellular homeostasis;GO:0051260//protein homooligomerization "gi|568991691|ref|XP_006520664.1|/0/PREDICTED: ATP-dependent 6-phosphofructokinase, muscle type isoform X2 [Mus musculus]" 320176 1314 0.08 0.326666667 2.029747343 Up 0.331405845 D930032P07Rik RIKEN cDNA D930032P07 gene - - - - "gi|148709711|gb|EDL41657.1|/9.65623e-38/mCG145650, partial [Mus musculus]" 245860 3857.41 47.87 52.77666667 0.140778428 Up 0.331330625 Atg9a autophagy related 9A K17907|1|0.0|1176|mmu:245860|autophagy-related protein 9 GO:0031224//intrinsic component of membrane;GO:0005774//vacuolar membrane;GO:0031982//vesicle;GO:0005770//late endosome;GO:0031224//intrinsic component of membrane;GO:0005774//vacuolar membrane;GO:0031982//vesicle;GO:0005770//late endosome;GO:0031224//intrinsic component of membrane;GO:0005774//vacuolar membrane;GO:0031982//vesicle;GO:0005770//late endosome;GO:0031224//intrinsic component of membrane;GO:0005774//vacuolar membrane;GO:0031982//vesicle;GO:0005770//late endosome - GO:0006952//defense response;GO:0044248;GO:0045184//establishment of protein localization;GO:0033365//protein localization to organelle;GO:0007033//vacuole organization;GO:0006952//defense response;GO:0044248;GO:0045184//establishment of protein localization;GO:0033365//protein localization to organelle;GO:0007033//vacuole organization;GO:0006952//defense response;GO:0044248;GO:0045184//establishment of protein localization;GO:0033365//protein localization to organelle;GO:0007033//vacuole organization;GO:0006952//defense response;GO:0044248;GO:0045184//establishment of protein localization;GO:0033365//protein localization to organelle;GO:0007033//vacuole organization gi|731283160|ref|XP_010610152.1|/0/PREDICTED: autophagy-related protein 9A isoform X1 [Fukomys damarensis] 97998 8549 1.8 2.35 0.38466385 Up 0.331321223 Deptor DEP domain containing MTOR-interacting protein K20402|1|0.0|656|mmu:97998|DEP domain-containing mTOR-interacting protein - - - - 58520 1185 2.906666667 3.576666667 0.299250036 Up 0.331255406 0610007P14Rik RIKEN cDNA 0610007P14 gene - "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane" - GO:0006694//steroid biosynthetic process gi|531997756|ref|XP_005343433.1|/1.54534e-76/PREDICTED: probable ergosterol biosynthetic protein 28 [Microtus ochrogaster] 319314 1126 3.553333333 2.88 -0.303104221 Down 0.331255406 A930001C03Rik RIKEN cDNA A930001C03 gene K19912|1|4e-24|114|mmu:171180|synaptotagmin-12 - - - - 52174 1497 18.13666667 20.29 0.161859537 Up 0.331067359 Tmem222 transmembrane protein 222 "K05720|1|3e-43|178|nvi:100122250|FYVE, RhoGEF and PH domain containing 1" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|148277088|ref|NP_079943.2|/2.00788e-114/transmembrane protein 222 [Mus musculus] 63856 2779 5.37 6.293333333 0.228902271 Up 0.331057956 Taf8 TATA-box binding protein associated factor 8 K14649|1|1e-139|500|mmu:63856|transcription initiation factor TFIID subunit 8 GO:0005667//transcription factor complex;GO:0044444//cytoplasmic part GO:0046983//protein dimerization activity "GO:0001832//blastocyst growth;GO:0034504//protein localization to nucleus;GO:0006351//transcription, DNA-templated;GO:0045444//fat cell differentiation" gi|913505264|ref|XP_013206417.1|/3.38753e-140/PREDICTED: transcription initiation factor TFIID subunit 8 isoform X1 [Microtus ochrogaster] 11793 2396 6.353333333 5.433333333 -0.225676155 Down 0.331057956 Atg5 autophagy related 5 K08339|1|8e-159|563|mmu:11793|autophagy-related protein 5 - - - - 71007 2425 1.2 1.673333333 0.479690458 Up 0.33095453 D7Ertd443e "DNA segment, Chr 7, ERATO Doi 443, expressed" K16773|1|0.0|1124|mmu:71007|fragile-site associated tumor suppressor GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center GO:0019899//enzyme binding;GO:0019899//enzyme binding GO:0016049//cell growth;GO:0031572//G2 DNA damage checkpoint;GO:0009416//response to light stimulus;GO:0031647//regulation of protein stability;GO:0016049//cell growth;GO:0031572//G2 DNA damage checkpoint;GO:0009416//response to light stimulus;GO:0031647//regulation of protein stability gi|755523122|ref|XP_011240205.1|/0/PREDICTED: centrosomal protein C10orf90 homolog isoform X4 [Mus musculus] 109077 3294 5.843333333 6.823333333 0.223685106 Up 0.330813494 Ints5 integrator complex subunit 5 K13142|1|0.0|1640|mmu:109077|integrator complex subunit 5 "GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0031224//intrinsic component of membrane" - GO:0016073//snRNA metabolic process gi|28849895|ref|NP_789813.1|/0/integrator complex subunit 5 [Mus musculus] 14297 1095 48.47 53.25333333 0.13577975 Up 0.330813494 Fxn frataxin K19054|1|3e-118|427|mmu:14297|frataxin [EC:1.16.3.1] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0016724;GO:0051536//iron-sulfur cluster binding;GO:0005506//iron ion binding GO:0030307//positive regulation of cell growth;GO:0051339;GO:0043085//positive regulation of catalytic activity;GO:0034614//cellular response to reactive oxygen species;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0035265//organ growth;GO:0010823//negative regulation of mitochondrion organization;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0016226//iron-sulfur cluster assembly;GO:0016485//protein processing;GO:0045333//cellular respiration;GO:0010038//response to metal ion;GO:0009790//embryo development;GO:0044765//single-organism transport;GO:0007600//sensory perception;GO:0035264//multicellular organism growth;GO:0006875//cellular metal ion homeostasis;GO:0008344//adult locomotory behavior "gi|6679863|ref|NP_032070.1|/2.7405e-117/frataxin, mitochondrial precursor [Mus musculus]" 18597 2872 379.22 345.61 -0.133890092 Down 0.330766482 Pdha1 pyruvate dehydrogenase E1 alpha 1 K00161|1|0.0|763|mmu:18597|pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1] - - - - 16206 4966 10.25 8.966666667 -0.192980238 Down 0.330728873 Lrig1 leucine-rich repeats and immunoglobulin-like domains 1 K19511|1|9e-57|225|ssc:100516076|peroxidase [EC:1.11.1.7] GO:0031224//intrinsic component of membrane - - gi|88014689|ref|NP_032403.2|/0/leucine-rich repeats and immunoglobulin-like domains protein 1 precursor [Mus musculus] 64213 2079.12 9.086666667 10.36666667 0.190129018 Up 0.330728873 St7 suppression of tumorigenicity 7 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|575771826|ref|NP_001276558.1|/0/suppressor of tumorigenicity 7 protein isoform 7 [Mus musculus] 13388 3444 1.943333333 1.446666667 -0.425800841 Down 0.330700666 Dll1 delta-like 1 (Drosophila) K06051|1|0.0|1481|mmu:13388|delta GO:0031982//vesicle;GO:0031224//intrinsic component of membrane GO:0005102//receptor binding;GO:0046872//metal ion binding GO:0007219//Notch signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0001756//somitogenesis;GO:0042476//odontogenesis;GO:0009855//determination of bilateral symmetry;GO:0019827//stem cell population maintenance;GO:0003143//embryonic heart tube morphogenesis;GO:0009798//axis specification;GO:0030099//myeloid cell differentiation;GO:0042471//ear morphogenesis;GO:0072080//nephron tubule development;GO:0042491//auditory receptor cell differentiation gi|40789272|ref|NP_031891.2|/0/delta-like protein 1 precursor [Mus musculus] 74165 3935 12.73333333 11.26333333 -0.176976288 Down 0.330691263 Fbxl22 F-box and leucine-rich repeat protein 22 K10288|1|2e-129|466|mmu:74165|F-box and leucine-rich repeat protein 22 GO:0044424 - - "gi|148694175|gb|EDL26122.1|/7.04346e-137/F-box and leucine-rich repeat protein 22, partial [Mus musculus]" 28019 1617 13.91333333 15.62333333 0.167234194 Up 0.330634849 Ing4 "inhibitor of growth family, member 4" K11346|1|1e-132|476|mmu:28019|inhibitor of growth protein 4 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0003712//transcription cofactor activity "GO:0006351//transcription, DNA-templated;GO:0043967//histone H4 acetylation;GO:0040007//growth;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0006259//DNA metabolic process;GO:0022402//cell cycle process;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|612052087|ref|XP_007503719.1|/4.75274e-133/PREDICTED: inhibitor of growth protein 4 isoform X3 [Monodelphis domestica] 11482 3596.72 20.52666667 18.39666667 -0.158054982 Down 0.330625447 Acvrl1 "activin A receptor, type II-like 1" K13594|1|0.0|989|mmu:11482|activin receptor-like kinase 1 [EC:2.7.11.30] GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0044297//cell body;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0044297//cell body;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0044297//cell body;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0044297//cell body;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0044297//cell body GO:0005024//transforming growth factor beta-activated receptor activity;GO:0017002//activin-activated receptor activity;GO:0019900//kinase binding;GO:0032403//protein complex binding;GO:0032550;GO:0019838//growth factor binding;GO:0043169//cation binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0017002//activin-activated receptor activity;GO:0019900//kinase binding;GO:0032403//protein complex binding;GO:0032550;GO:0019838//growth factor binding;GO:0043169//cation binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0017002//activin-activated receptor activity;GO:0019900//kinase binding;GO:0032403//protein complex binding;GO:0032550;GO:0019838//growth factor binding;GO:0043169//cation binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0017002//activin-activated receptor activity;GO:0019900//kinase binding;GO:0032403//protein complex binding;GO:0032550;GO:0019838//growth factor binding;GO:0043169//cation binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0017002//activin-activated receptor activity;GO:0019900//kinase binding;GO:0032403//protein complex binding;GO:0032550;GO:0019838//growth factor binding;GO:0043169//cation binding "GO:0001775//cell activation;GO:0001935//endothelial cell proliferation;GO:0030858//positive regulation of epithelial cell differentiation;GO:0043009//chordate embryonic development;GO:0001945//lymph vessel development;GO:0016049//cell growth;GO:0010596//negative regulation of endothelial cell migration;GO:0044319//wound healing, spreading of cells;GO:0051053//negative regulation of DNA metabolic process;GO:0001934//positive regulation of protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0030857//negative regulation of epithelial cell differentiation;GO:0048771//tissue remodeling;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0003159;GO:0071363//cellular response to growth factor stimulus;GO:0008015//blood circulation;GO:0051259//protein oligomerization;GO:0001953//negative regulation of cell-matrix adhesion;GO:0001568//blood vessel development;GO:0001775//cell activation;GO:0001935//endothelial cell proliferation;GO:0030858//positive regulation of epithelial cell differentiation;GO:0043009//chordate embryonic development;GO:0001945//lymph vessel development;GO:0016049//cell growth;GO:0010596//negative regulation of endothelial cell migration;GO:0044319//wound healing, spreading of cells;GO:0051053//negative regulation of DNA metabolic process;GO:0001934//positive regulation of protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0030857//negative regulation of epithelial cell differentiation;GO:0048771//tissue remodeling;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0003159;GO:0071363//cellular response to growth factor stimulus;GO:0008015//blood circulation;GO:0051259//protein oligomerization;GO:0001953//negative regulation of cell-matrix adhesion;GO:0001568//blood vessel development;GO:0001775//cell activation;GO:0001935//endothelial cell proliferation;GO:0030858//positive regulation of epithelial cell differentiation;GO:0043009//chordate embryonic development;GO:0001945//lymph vessel development;GO:0016049//cell growth;GO:0010596//negative regulation of endothelial cell migration;GO:0044319//wound healing, spreading of cells;GO:0051053//negative regulation of DNA metabolic process;GO:0001934//positive regulation of protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0030857//negative regulation of epithelial cell differentiation;GO:0048771//tissue remodeling;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0003159;GO:0071363//cellular response to growth factor stimulus;GO:0008015//blood circulation;GO:0051259//protein oligomerization;GO:0001953//negative regulation of cell-matrix adhesion;GO:0001568//blood vessel development;GO:0001775//cell activation;GO:0001935//endothelial cell proliferation;GO:0030858//positive regulation of epithelial cell differentiation;GO:0043009//chordate embryonic development;GO:0001945//lymph vessel development;GO:0016049//cell growth;GO:0010596//negative regulation of endothelial cell migration;GO:0044319//wound healing, spreading of cells;GO:0051053//negative regulation of DNA metabolic process;GO:0001934//positive regulation of protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0030857//negative regulation of epithelial cell differentiation;GO:0048771//tissue remodeling;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0003159;GO:0071363//cellular response to growth factor stimulus;GO:0008015//blood circulation;GO:0051259//protein oligomerization;GO:0001953//negative regulation of cell-matrix adhesion;GO:0001568//blood vessel development;GO:0001775//cell activation;GO:0001935//endothelial cell proliferation;GO:0030858//positive regulation of epithelial cell differentiation;GO:0043009//chordate embryonic development;GO:0001945//lymph vessel development;GO:0016049//cell growth;GO:0010596//negative regulation of endothelial cell migration;GO:0044319//wound healing, spreading of cells;GO:0051053//negative regulation of DNA metabolic process;GO:0001934//positive regulation of protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0030857//negative regulation of epithelial cell differentiation;GO:0048771//tissue remodeling;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0003159;GO:0071363//cellular response to growth factor stimulus;GO:0008015//blood circulation;GO:0051259//protein oligomerization;GO:0001953//negative regulation of cell-matrix adhesion;GO:0001568//blood vessel development" "gi|148672117|gb|EDL04064.1|/0/activin A receptor, type II-like 1, isoform CRA_c, partial [Mus musculus]" 17274 2012 18.58333333 20.71333333 0.156550436 Up 0.330625447 Rab8a "RAB8A, member RAS oncogene family" K07901|1|3e-116|421|pale:102888123|Ras-related protein Rab-8A GO:0030666//endocytic vesicle membrane;GO:0005815//microtubule organizing center;GO:0044327//dendritic spine head;GO:0044297//cell body;GO:0072372//primary cilium;GO:0005768//endosome GO:0032550;GO:0017016//Ras GTPase binding;GO:0019900//kinase binding GO:0048168//regulation of neuronal synaptic plasticity;GO:0006906//vesicle fusion;GO:0015031//protein transport;GO:0006887//exocytosis;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0010927;GO:0035556//intracellular signal transduction gi|759139657|ref|XP_011365196.1|/7.38684e-116/PREDICTED: ras-related protein Rab-8A [Pteropus vampyrus] 74048 4846 9.06 7.9 -0.197658397 Down 0.330531423 Vsir V-set immunoregulatory receptor - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|47847392|dbj|BAD21368.1|/9.70417e-168/mFLJ00041 protein [Mus musculus] 67041 3496 353.7566667 323.3566667 -0.129630981 Down 0.33052202 Oxct1 3-oxoacid CoA transferase 1 K01027|1|0.0|919|mmu:67041|3-oxoacid CoA-transferase [EC:2.8.3.5] GO:0044429 GO:0042802//identical protein binding;GO:0008410//CoA-transferase activity GO:0007417//central nervous system development;GO:0050796//regulation of insulin secretion;GO:0048513//animal organ development;GO:0001101//response to acid chemical;GO:0097305//response to alcohol;GO:0042180//cellular ketone metabolic process;GO:0009719;GO:0044767//single-organism developmental process;GO:0006950//response to stress;GO:0001678//cellular glucose homeostasis;GO:0044248;GO:0031667//response to nutrient levels "gi|18266680|ref|NP_077150.1|/0/succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial precursor [Mus musculus]" 29856 3335.9 50.61666667 45.93 -0.140175719 Down 0.330427997 Smtn smoothelin K10314|1|3e-51|206|bacu:103002192|F-box protein 39;K05699|2|2e-22|110|clv:102088244|actinin alpha GO:0043232;GO:0043232;GO:0043232;GO:0043232;GO:0043232 - - gi|226529455|ref|NP_001152756.1|/0/smoothelin isoform b [Mus musculus] 12847 4629 52.03 47.35 -0.135979282 Down 0.330427997 Copa coatomer protein complex subunit alpha K05236|1|0.0|2465|mmu:12847|coatomer subunit alpha GO:0030120//vesicle coat;GO:0044421 - GO:0007589//body fluid secretion;GO:0015031//protein transport "gi|873090748|pdb|5A1U|C/0/Chain C, The Structure Of The Copi Coat Triad" 13495 1713 26.1 28.93666667 0.148848935 Up 0.330409192 Drg2 developmentally regulated GTP binding protein 2 K06944|1|0.0|655|rno:497915|uncharacterized protein GO:0043231//intracellular membrane-bounded organelle GO:0032550 GO:0007154//cell communication gi|10946678|ref|NP_067329.1|/0/developmentally-regulated GTP-binding protein 2 [Mus musculus] 68607 1391 28.89666667 26.05666667 -0.149250545 Down 0.330409192 Serhl serine hydrolase-like K13703|1|2e-06|56.2|nve:NEMVE_v1g94848|abhydrolase domain-containing protein 11 - - - - 319181 464 1.013333333 0.626666667 -0.693338662 Down 0.33036218 Hist1h2bg "histone cluster 1, H2bg" K11252|1|5e-46|184|cge:100761268|histone H2B GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|344238174|gb|EGV94277.1|/3.60738e-45/histone H2B type 1 [Cricetulus griseus] 72041 1726 2.086666667 2.663333333 0.352032846 Up 0.330352777 Alkbh4 "alkB homolog 4, lysine demethylase" K10766|1|7e-104|380|mmu:72041|alkylated DNA repair protein alkB homolog 4 [EC:1.14.11.-] - - - - 54131 2088.91 13.46333333 15.16666667 0.171868399 Up 0.330286961 Irf3 interferon regulatory factor 3 K05411|1|0.0|871|mmu:54131|interferon regulatory factor 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0000975//regulatory region DNA binding GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0050663//cytokine secretion;GO:0006366//transcription from RNA polymerase II promoter;GO:0050687//negative regulation of defense response to virus;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043331//response to dsRNA;GO:0002237//response to molecule of bacterial origin;GO:0042036//negative regulation of cytokine biosynthetic process;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:0050663//cytokine secretion;GO:0006366//transcription from RNA polymerase II promoter;GO:0050687//negative regulation of defense response to virus;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043331//response to dsRNA;GO:0002237//response to molecule of bacterial origin;GO:0042036//negative regulation of cytokine biosynthetic process gi|8393627|ref|NP_058545.1|/0/interferon regulatory factor 3 [Mus musculus] 67863 1869 321.1366667 292.94 -0.132582196 Down 0.330286961 Slc25a11 "solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11" "K15104|1|5e-177|623|mmu:67863|solute carrier family 25 (mitochondrial oxoglutarate transporter), member 11" GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0051234//establishment of localization gi|21312994|ref|NP_077173.1|/4.21128e-176/mitochondrial 2-oxoglutarate/malate carrier protein [Mus musculus] 17750 556 320.9033333 292.67 -0.132863905 Down 0.330286961 Mt2 metallothionein 2 - - - - "gi|148679170|gb|EDL11117.1|/1.5517e-42/metallothionein 2, partial [Mus musculus]" 101476 3321 12.80666667 11.34333333 -0.175050368 Down 0.330268156 Plekha1 "pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1" K01530|1|2e-12|78.2|xma:102225698|phospholipid-translocating ATPase [EC:3.6.3.1];K12229|2|8e-11|72.4|tru:101065486|dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0001726//ruffle GO:0019904//protein domain specific binding;GO:0043168//anion binding;GO:0008289//lipid binding GO:0009653//anatomical structure morphogenesis;GO:0001501//skeletal system development;GO:0008202//steroid metabolic process;GO:0040007//growth;GO:0034614//cellular response to reactive oxygen species;GO:0050851//antigen receptor-mediated signaling pathway;GO:0008585//female gonad development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030030//cell projection organization;GO:0008104//protein localization;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048232//male gamete generation gi|19527162|ref|NP_598703.1|/3.99691e-178/pleckstrin homology domain-containing family A member 1 [Mus musculus] 20524 1667 9.253333333 10.52666667 0.186003603 Up 0.330239949 Slc25a17 "solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17" "K13354|1|1e-145|519|mmu:20524|solute carrier family 25 (peroxisomal adenine nucleotide transporter), member 17" GO:0031231//intrinsic component of peroxisomal membrane GO:0000295//adenine nucleotide transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity;GO:0005515//protein binding;GO:0051184 GO:0044763;GO:0015883//FAD transport;GO:0009062//fatty acid catabolic process;GO:0006869//lipid transport;GO:0015695//organic cation transport;GO:0015880//coenzyme A transport gi|29789024|ref|NP_035529.1|/9.63404e-145/peroxisomal membrane protein PMP34 [Mus musculus] 71687 2354 6.183333333 5.273333333 -0.229669587 Down 0.330098913 Tmem25 transmembrane protein 25 - GO:0031224//intrinsic component of membrane - - "gi|148693671|gb|EDL25618.1|/0/transmembrane protein 25, isoform CRA_b, partial [Mus musculus]" 22354 4929 0.773333333 0.423333333 -0.869296308 Down 0.330080108 Vipr1 vasoactive intestinal peptide receptor 1 K04589|1|0.0|892|mmu:22354|vasoactive intestinal peptide receptor 1 GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway gi|31543948|ref|NP_035833.2|/0/vasoactive intestinal polypeptide receptor 1 precursor [Mus musculus] 12445 2012.09 44.64333333 49.21666667 0.140702199 Up 0.329901463 Ccnd3 cyclin D3 K10152|1|2e-141|505|mmu:12445|cyclin D3 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0004674//protein serine/threonine kinase activity;GO:0019900//kinase binding;GO:0004674//protein serine/threonine kinase activity;GO:0019900//kinase binding;GO:0004674//protein serine/threonine kinase activity;GO:0019900//kinase binding GO:0044772//mitotic cell cycle phase transition;GO:0008283//cell proliferation;GO:0007154//cell communication;GO:0042110//T cell activation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006024//glycosaminoglycan biosynthetic process;GO:0009746;GO:0009725//response to hormone;GO:0044772//mitotic cell cycle phase transition;GO:0008283//cell proliferation;GO:0007154//cell communication;GO:0042110//T cell activation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006024//glycosaminoglycan biosynthetic process;GO:0009746;GO:0009725//response to hormone;GO:0044772//mitotic cell cycle phase transition;GO:0008283//cell proliferation;GO:0007154//cell communication;GO:0042110//T cell activation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006024//glycosaminoglycan biosynthetic process;GO:0009746;GO:0009725//response to hormone gi|344250708|gb|EGW06812.1|/3.816e-144/G1/S-specific cyclin-D3 [Cricetulus griseus] 12626 1013 12.18333333 10.73 -0.183258829 Down 0.329882658 Cetn3 centrin 3 K16466|1|6e-89|329|rno:170895|centrin-3 GO:0031513//nonmotile primary cilium;GO:0005813//centrosome GO:0046872//metal ion binding;GO:0032403//protein complex binding;GO:0015631//tubulin binding GO:0000087//mitotic M phase gi|731244647|ref|XP_010635480.1|/7.31809e-90/PREDICTED: centrin-3 isoform X2 [Fukomys damarensis] 14113 1159 24.82666667 27.61 0.153300316 Up 0.329816842 Fbl fibrillarin K14563|1|1e-135|485|myd:102773914|rRNA 2'-O-methyltransferase fibrillarin [EC:2.1.1.-] - - - gi|675718617|ref|XP_008963199.1|/9.21876e-135/PREDICTED: rRNA 2'-O-methyltransferase fibrillarin isoform X3 [Pan paniscus] 116904 6369 49.81 45.26333333 -0.138092578 Down 0.329816842 Alpk3 alpha-kinase 3 K08868|1|0.0|2993|mmu:116904|alpha-kinase GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0044767//single-organism developmental process gi|117938324|ref|NP_473426.2|/0/alpha-protein kinase 3 [Mus musculus] 11816 1288.04 266.3966667 290.55 0.125210424 Up 0.329760427 Apoe apolipoprotein E K04524|1|5e-166|586|mmu:11816|apolipoprotein E GO:0015630//microtubule cytoskeleton;GO:0009897//external side of plasma membrane;GO:0005768//endosome;GO:0043005//neuron projection;GO:0034385;GO:0044297//cell body;GO:0015630//microtubule cytoskeleton;GO:0009897//external side of plasma membrane;GO:0005768//endosome;GO:0043005//neuron projection;GO:0034385;GO:0044297//cell body;GO:0015630//microtubule cytoskeleton;GO:0009897//external side of plasma membrane;GO:0005768//endosome;GO:0043005//neuron projection;GO:0034385;GO:0044297//cell body;GO:0015630//microtubule cytoskeleton;GO:0009897//external side of plasma membrane;GO:0005768//endosome;GO:0043005//neuron projection;GO:0034385;GO:0044297//cell body GO:0008289//lipid binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0070325//lipoprotein particle receptor binding;GO:0008047//enzyme activator activity;GO:0008092//cytoskeletal protein binding;GO:0042277//peptide binding;GO:0015248//sterol transporter activity;GO:0046983//protein dimerization activity;GO:0071814;GO:0005539//glycosaminoglycan binding;GO:0008289//lipid binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0070325//lipoprotein particle receptor binding;GO:0008047//enzyme activator activity;GO:0008092//cytoskeletal protein binding;GO:0042277//peptide binding;GO:0015248//sterol transporter activity;GO:0046983//protein dimerization activity;GO:0071814;GO:0005539//glycosaminoglycan binding;GO:0008289//lipid binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0070325//lipoprotein particle receptor binding;GO:0008047//enzyme activator activity;GO:0008092//cytoskeletal protein binding;GO:0042277//peptide binding;GO:0015248//sterol transporter activity;GO:0046983//protein dimerization activity;GO:0071814;GO:0005539//glycosaminoglycan binding;GO:0008289//lipid binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0070325//lipoprotein particle receptor binding;GO:0008047//enzyme activator activity;GO:0008092//cytoskeletal protein binding;GO:0042277//peptide binding;GO:0015248//sterol transporter activity;GO:0046983//protein dimerization activity;GO:0071814;GO:0005539//glycosaminoglycan binding GO:0030163//protein catabolic process;GO:0050880//regulation of blood vessel size;GO:0036315//cellular response to sterol;GO:0031103//axon regeneration;GO:0006182//cGMP biosynthetic process;GO:0010596//negative regulation of endothelial cell migration;GO:0006875//cellular metal ion homeostasis;GO:0070555//response to interleukin-1;GO:0010543//regulation of platelet activation;GO:0055092//sterol homeostasis;GO:0006897//endocytosis;GO:0043434//response to peptide hormone;GO:0043066//negative regulation of apoptotic process;GO:0015914//phospholipid transport;GO:0006509//membrane protein ectodomain proteolysis;GO:0034370//triglyceride-rich lipoprotein particle remodeling;GO:0071830;GO:0006954//inflammatory response;GO:0007166//cell surface receptor signaling pathway;GO:0032270//positive regulation of cellular protein metabolic process;GO:0010874//regulation of cholesterol efflux;GO:0034377//plasma lipoprotein particle assembly;GO:0007417//central nervous system development;GO:0048514//blood vessel morphogenesis;GO:0010467//gene expression;GO:0010872//regulation of cholesterol esterification;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0040014//regulation of multicellular organism growth;GO:0030307//positive regulation of cell growth;GO:0032770//positive regulation of monooxygenase activity;GO:0032488//Cdc42 protein signal transduction;GO:0006695//cholesterol biosynthetic process;GO:0034645//cellular macromolecule biosynthetic process;GO:0001935//endothelial cell proliferation;GO:0070848//response to growth factor;GO:0012502//induction of programmed cell death;GO:0043405//regulation of MAP kinase activity;GO:0006639//acylglycerol metabolic process;GO:0030163//protein catabolic process;GO:0050880//regulation of blood vessel size;GO:0036315//cellular response to sterol;GO:0031103//axon regeneration;GO:0006182//cGMP biosynthetic process;GO:0010596//negative regulation of endothelial cell migration;GO:0006875//cellular metal ion homeostasis;GO:0070555//response to interleukin-1;GO:0010543//regulation of platelet activation;GO:0055092//sterol homeostasis;GO:0006897//endocytosis;GO:0043434//response to peptide hormone;GO:0043066//negative regulation of apoptotic process;GO:0015914//phospholipid transport;GO:0006509//membrane protein ectodomain proteolysis;GO:0034370//triglyceride-rich lipoprotein particle remodeling;GO:0071830;GO:0006954//inflammatory response;GO:0007166//cell surface receptor signaling pathway;GO:0032270//positive regulation of cellular protein metabolic process;GO:0010874//regulation of cholesterol efflux;GO:0034377//plasma lipoprotein particle assembly;GO:0007417//central nervous system development;GO:0048514//blood vessel morphogenesis;GO:0010467//gene expression;GO:0010872//regulation of cholesterol esterification;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0040014//regulation of multicellular organism growth;GO:0030307//positive regulation of cell growth;GO:0032770//positive regulation of monooxygenase activity;GO:0032488//Cdc42 protein signal transduction;GO:0006695//cholesterol biosynthetic process;GO:0034645//cellular macromolecule biosynthetic process;GO:0001935//endothelial cell proliferation;GO:0070848//response to growth factor;GO:0012502//induction of programmed cell death;GO:0043405//regulation of MAP kinase activity;GO:0006639//acylglycerol metabolic process;GO:0030163//protein catabolic process;GO:0050880//regulation of blood vessel size;GO:0036315//cellular response to sterol;GO:0031103//axon regeneration;GO:0006182//cGMP biosynthetic process;GO:0010596//negative regulation of endothelial cell migration;GO:0006875//cellular metal ion homeostasis;GO:0070555//response to interleukin-1;GO:0010543//regulation of platelet activation;GO:0055092//sterol homeostasis;GO:0006897//endocytosis;GO:0043434//response to peptide hormone;GO:0043066//negative regulation of apoptotic process;GO:0015914//phospholipid transport;GO:0006509//membrane protein ectodomain proteolysis;GO:0034370//triglyceride-rich lipoprotein particle remodeling;GO:0071830;GO:0006954//inflammatory response;GO:0007166//cell surface receptor signaling pathway;GO:0032270//positive regulation of cellular protein metabolic process;GO:0010874//regulation of cholesterol efflux;GO:0034377//plasma lipoprotein particle assembly;GO:0007417//central nervous system development;GO:0048514//blood vessel morphogenesis;GO:0010467//gene expression;GO:0010872//regulation of cholesterol esterification;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0040014//regulation of multicellular organism growth;GO:0030307//positive regulation of cell growth;GO:0032770//positive regulation of monooxygenase activity;GO:0032488//Cdc42 protein signal transduction;GO:0006695//cholesterol biosynthetic process;GO:0034645//cellular macromolecule biosynthetic process;GO:0001935//endothelial cell proliferation;GO:0070848//response to growth factor;GO:0012502//induction of programmed cell death;GO:0043405//regulation of MAP kinase activity;GO:0006639//acylglycerol metabolic process;GO:0030163//protein catabolic process;GO:0050880//regulation of blood vessel size;GO:0036315//cellular response to sterol;GO:0031103//axon regeneration;GO:0006182//cGMP biosynthetic process;GO:0010596//negative regulation of endothelial cell migration;GO:0006875//cellular metal ion homeostasis;GO:0070555//response to interleukin-1;GO:0010543//regulation of platelet activation;GO:0055092//sterol homeostasis;GO:0006897//endocytosis;GO:0043434//response to peptide hormone;GO:0043066//negative regulation of apoptotic process;GO:0015914//phospholipid transport;GO:0006509//membrane protein ectodomain proteolysis;GO:0034370//triglyceride-rich lipoprotein particle remodeling;GO:0071830;GO:0006954//inflammatory response;GO:0007166//cell surface receptor signaling pathway;GO:0032270//positive regulation of cellular protein metabolic process;GO:0010874//regulation of cholesterol efflux;GO:0034377//plasma lipoprotein particle assembly;GO:0007417//central nervous system development;GO:0048514//blood vessel morphogenesis;GO:0010467//gene expression;GO:0010872//regulation of cholesterol esterification;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0040014//regulation of multicellular organism growth;GO:0030307//positive regulation of cell growth;GO:0032770//positive regulation of monooxygenase activity;GO:0032488//Cdc42 protein signal transduction;GO:0006695//cholesterol biosynthetic process;GO:0034645//cellular macromolecule biosynthetic process;GO:0001935//endothelial cell proliferation;GO:0070848//response to growth factor;GO:0012502//induction of programmed cell death;GO:0043405//regulation of MAP kinase activity;GO:0006639//acylglycerol metabolic process gi|163644329|ref|NP_033826.2|/4.49125e-165/apolipoprotein E precursor [Mus musculus] 14109 575.32 249.7066667 273.2733333 0.130110346 Up 0.329657001 Fau Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived) K02983|1|1e-56|221|mmu:14109|small subunit ribosomal protein S30e GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit;GO:0015935//small ribosomal subunit GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity;GO:0003676//nucleic acid binding;GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane;GO:0010467//gene expression gi|15822914|dbj|BAB68608.1|/4.17007e-57/fau [Mus musculus domesticus] 270190 4686 1.676666667 1.206666667 -0.474568703 Down 0.329638196 Ephb1 Eph receptor B1 K05110|1|0.0|1880|mmu:270190|Eph receptor B1 [EC:2.7.10.1] GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0005769//early endosome;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0005769//early endosome GO:0032550;GO:0005003//ephrin receptor activity;GO:0032550;GO:0005003//ephrin receptor activity GO:0007411//axon guidance;GO:0016358//dendrite development;GO:0007163//establishment or maintenance of cell polarity;GO:0021554//optic nerve development;GO:0007155//cell adhesion;GO:0043010//camera-type eye development;GO:0008283//cell proliferation;GO:0043408//regulation of MAPK cascade;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007254//JNK cascade;GO:0006468//protein phosphorylation;GO:0019233//sensory perception of pain;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0007416//synapse assembly;GO:0021955//central nervous system neuron axonogenesis;GO:0007411//axon guidance;GO:0016358//dendrite development;GO:0007163//establishment or maintenance of cell polarity;GO:0021554//optic nerve development;GO:0007155//cell adhesion;GO:0043010//camera-type eye development;GO:0008283//cell proliferation;GO:0043408//regulation of MAPK cascade;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007254//JNK cascade;GO:0006468//protein phosphorylation;GO:0019233//sensory perception of pain;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0007416//synapse assembly;GO:0021955//central nervous system neuron axonogenesis "gi|148689100|gb|EDL21047.1|/0/Eph receptor B1, isoform CRA_b, partial [Mus musculus]" 57432 1615 2.213333333 2.8 0.339206086 Up 0.329609989 Zc3h8 zinc finger CCCH type containing 8 K15687|1|2e-07|60.1|ngi:103751449|E3 ubiquitin-protein ligase makorin [EC:2.3.2.27];K14404|4|2e-07|59.7|tad:TRIADDRAFT_53642|cleavage and polyadenylation specificity factor subunit 4 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0009636//response to toxic substance;GO:0070234//positive regulation of T cell apoptotic process;GO:0033077//T cell differentiation in thymus;GO:0002260//lymphocyte homeostasis" gi|85719326|ref|NP_065619.2|/7.08558e-137/zinc finger CCCH domain-containing protein 8 [Mus musculus] 433904 2510 2.863333333 3.523333333 0.29924534 Up 0.329591184 Ociad2 OCIA domain containing 2 - GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|537259578|gb|ERE89729.1|/4.90738e-77/OCIA domain-containing protein 2 [Cricetulus griseus] 68051 1966 11.06666667 12.51 0.176861049 Up 0.329468953 Nutf2 nuclear transport factor 2 K14285|1|6e-10|68.6|dgr:Dgri_GH13218|NTF2-related export protein 1/2 GO:0005856//cytoskeleton;GO:0005635//nuclear envelope;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0022892//substrate-specific transporter activity GO:0006886//intracellular protein transport gi|594689477|ref|XP_007192124.1|/1.87186e-75/PREDICTED: nuclear transport factor 2-like [Balaenoptera acutorostrata scammoni] 170787 2535 3.836666667 4.6 0.261780434 Up 0.329421941 Hdac10 histone deacetylase 10 K18671|1|0.0|511|mmu:170787|histone deacetylase 10 [EC:3.5.1.98] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0019899//enzyme binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0019899//enzyme binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0019899//enzyme binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0019899//enzyme binding;GO:0017136//NAD-dependent histone deacetylase activity GO:0006476//protein deacetylation;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006476//protein deacetylation;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006476//protein deacetylation;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006476//protein deacetylation;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter gi|568991559|ref|XP_006520600.1|/0/PREDICTED: histone deacetylase 10 isoform X1 [Mus musculus] 74626 1767 0.723333333 1.126666667 0.639328204 Up 0.329403137 Tmem81 transmembrane protein 81 - GO:0031224//intrinsic component of membrane - - gi|21312826|ref|NP_083301.1|/4.82424e-134/transmembrane protein 81 precursor [Mus musculus] 69590 1016 17.94 20.01 0.157541277 Up 0.329327918 Gpx8 glutathione peroxidase 8 (putative) K00432|1|8e-111|402|mmu:69590|glutathione peroxidase [EC:1.11.1.9] GO:0031224//intrinsic component of membrane GO:0004601//peroxidase activity GO:0044710;GO:0006950//response to stress "gi|148686451|gb|EDL18398.1|/4.00817e-112/RIKEN cDNA 2310016C16, partial [Mus musculus]" 52830 1907 25.34 28.07666667 0.147955141 Up 0.329309113 Pnrc2 proline-rich nuclear receptor coactivator 2 K18751|1|5e-66|254|mmu:52830|proline-rich nuclear receptor coactivator 2 GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule - "GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006351//transcription, DNA-templated" gi|13385876|ref|NP_080659.1|/4.0148e-65/proline-rich nuclear receptor coactivator 2 [Mus musculus] 227612 3428 3.063333333 3.74 0.287935909 Up 0.329215089 Tor4a "torsin family 4, member A" K15180|1|1e-16|91.7|fca:101084581|negative elongation factor B GO:0031224//intrinsic component of membrane GO:0016462//pyrophosphatase activity;GO:0032550 GO:0051084//'de novo' posttranslational protein folding gi|31981884|ref|NP_666227.2|/0/torsin-4A [Mus musculus] 74772 4310.71 7.663333333 8.806666667 0.200624001 Up 0.329177479 Atp13a2 ATPase type 13A2 K13526|1|0.0|2148|mmu:74772|cation-transporting ATPase 13A2 [EC:3.6.3.-] GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0008324//cation transmembrane transporter activity;GO:0043169//cation binding;GO:0008324//cation transmembrane transporter activity - gi|256985106|ref|NP_083373.2|/0/probable cation-transporting ATPase 13A2 isoform 1 [Mus musculus] 64143 2293 17.20666667 19.26666667 0.163139351 Up 0.329111663 Ralb v-ral simian leukemia viral oncogene B K07835|1|3e-106|388|mmu:64143|Ras-related protein Ral-B GO:0016020//membrane;GO:0044444//cytoplasmic part GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0012501//programmed cell death;GO:0048534//hematopoietic or lymphoid organ development;GO:0032880//regulation of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0001927//exocyst assembly;GO:0035556//intracellular signal transduction gi|11612509|ref|NP_071722.1|/2.93129e-105/ras-related protein Ral-B precursor [Mus musculus] 68197 693 217.8233333 238.34 0.129862591 Up 0.329111663 Ndufc2 "NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2" K03968|1|4e-67|256|mmu:68197|NADH dehydrogenase (ubiquinone) 1 subunit C2 GO:0031224//intrinsic component of membrane;GO:0005746//mitochondrial respiratory chain GO:0050136//NADH dehydrogenase (quinone) activity GO:0051234//establishment of localization;GO:0022904//respiratory electron transport chain gi|18859597|ref|NP_077182.1|/2.75637e-66/NADH dehydrogenase [ubiquinone] 1 subunit C2 [Mus musculus] 14894 1318 10.82 12.25 0.17908125 Up 0.32910226 Cfap20 cilia and flagella associated protein 20 - GO:0043231//intracellular membrane-bounded organelle - GO:0032502//developmental process gi|51491831|ref|NP_001003905.1|/4.42292e-107/cilia- and flagella-associated protein 20 [Bos taurus] 66925 1287 208.73 229.02 0.133835624 Up 0.329074053 Sdhd "succinate dehydrogenase complex, subunit D, integral membrane protein" K00237|1|2e-72|275|mmu:66925|succinate dehydrogenase (ubiquinone) membrane anchor subunit GO:0031224//intrinsic component of membrane;GO:0005746//mitochondrial respiratory chain GO:0046906//tetrapyrrole binding;GO:0043169//cation binding;GO:0048038//quinone binding GO:0009060//aerobic respiration;GO:0051234//establishment of localization "gi|27229021|ref|NP_080124.1|/1.69576e-71/succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial [Mus musculus]" 56626 2336 5.873333333 6.833333333 0.218409985 Up 0.329036444 Poll "polymerase (DNA directed), lambda" K03512|1|0.0|1087|mmu:56626|DNA polymerase lambda [EC:2.7.7.7 4.2.99.-] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0034061//DNA polymerase activity GO:0006281//DNA repair gi|9910500|ref|NP_064416.1|/0/DNA polymerase lambda [Mus musculus] 171282 2325 0.203333333 0.49 1.268935007 Up 0.328961225 Acot4 acyl-CoA thioesterase 4 K01068|1|0.0|798|mmu:171282|acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2] GO:0042579//microbody GO:0005515//protein binding;GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity GO:0046459//short-chain fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0043648//dicarboxylic acid metabolic process gi|6478485|gb|AAF13872.1|/0/peroxisomal long chain acyl-CoA thioesterase Ib [Mus musculus] 17087 603 2.66 3.303333333 0.312496311 Up 0.328867201 Ly96 lymphocyte antigen 96 K05400|1|9e-77|287|mmu:17087|lymphocyte antigen 96 GO:0016021//integral component of membrane;GO:0044421;GO:0016021//integral component of membrane;GO:0005576//extracellular region GO:0005488//binding;GO:0008329//signaling pattern recognition receptor activity;GO:0005488//binding;GO:0008329//signaling pattern recognition receptor activity GO:0032490//detection of molecule of bacterial origin;GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway;GO:0002833;GO:0032490//detection of molecule of bacterial origin;GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway;GO:0002833 gi|8393737|ref|NP_058619.1|/3.24569e-90/lymphocyte antigen 96 isoform A precursor [Mus musculus] 108101 2587 2.66 3.296666667 0.309581775 Up 0.328867201 Fermt3 fermitin family member 3 K17084|1|0.0|1182|mmu:108101|kindlin 3 - - - - 235130 5946 1.87 2.416666667 0.369980224 Up 0.328848396 Adamts15 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15" K08629|1|0.0|1966|mmu:235130|a disintegrin and metalloproteinase with thrombospondin motifs 15 [EC:3.4.24.-] GO:0031012//extracellular matrix "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process gi|71725383|ref|NP_001019310.1|/0/A disintegrin and metalloproteinase with thrombospondin motifs 15 precursor [Mus musculus] 208177 5651.58 2.15 1.626666667 -0.402418013 Down 0.328829591 Phldb2 "pleckstrin homology like domain, family B, member 2" K09486|1|1e-143|514|asn:102367994|hypoxia up-regulated 1;K16464|2|1e-10|72.4|mdo:100032480|centrosomal protein CEP250;K20478|3|2e-10|72.0|dre:557772|golgin subfamily B member 1 GO:0044424;GO:0044424 GO:0008289//lipid binding;GO:0008289//lipid binding - "gi|148665664|gb|EDK98080.1|/0/pleckstrin homology-like domain, family B, member 2 [Mus musculus]" 78248 2316.68 1.22 0.806666667 -0.596836601 Down 0.328829591 Armcx1 "armadillo repeat containing, X-linked 1" - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148688430|gb|EDL20377.1|/0/armadillo repeat containing, X-linked 1, isoform CRA_a, partial [Mus musculus]" 76992 708 7.553333333 6.51 -0.214455912 Down 0.328801384 Fam219aos "family with sequence similarity 219, member A, opposite strand" - - - - - 245877 3241.67 201.7533333 220.5466667 0.128491446 Up 0.328763774 Map7d1 MAP7 domain containing 1 K16806|1|0.0|734|mmu:245877|MAP7 domain-containing protein 1 - - - "gi|148698349|gb|EDL30296.1|/0/arginine/proline rich coiled-coil 1, isoform CRA_b, partial [Mus musculus]" 80795 1018 43.97 48.28666667 0.135105342 Up 0.328688555 Selk selenoprotein K - - - - - 20557 1834 0.543333333 0.243333333 -1.158903595 Down 0.328679153 Slfn3 schlafen 3 - - - - gi|755537862|ref|XP_006532720.2|/0/PREDICTED: schlafen 3 isoform X2 [Mus musculus] 16909 1542.37 10.74333333 12.16 0.178701541 Up 0.328632141 Lmo2 LIM domain only 2 K15612|1|2e-101|372|rno:362176|rhombotin-2 GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex "GO:0046914//transition metal ion binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0046914//transition metal ion binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0046914//transition metal ion binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0046914//transition metal ion binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0000976//transcription regulatory region sequence-specific DNA binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0030218//erythrocyte differentiation;GO:0032870//cellular response to hormone stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0030218//erythrocyte differentiation;GO:0032870//cellular response to hormone stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0030218//erythrocyte differentiation;GO:0032870//cellular response to hormone stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0030218//erythrocyte differentiation;GO:0032870//cellular response to hormone stimulus gi|215272415|ref|NP_032531.2|/6.41315e-100/rhombotin-2 isoform 1 [Mus musculus] 28064 2035 41.17333333 45.48666667 0.143733464 Up 0.328613336 Yipf3 "Yip1 domain family, member 3" K15149|1|1e-10|71.2|tca:659337|mediator of RNA polymerase II transcription subunit 9;K03027|2|3e-06|56.2|cjo:107311332|DNA-directed RNA polymerases I and III subunit RPAC1 "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031224//intrinsic component of membrane" - GO:0048869//cellular developmental process "gi|148691538|gb|EDL23485.1|/0/Yip1 domain family, member 3, isoform CRA_a, partial [Mus musculus]" 65964 6679.27 23.97333333 26.64666667 0.152524552 Up 0.328528715 Zak sterile alpha motif and leucine zipper containing kinase AZK K04424|1|3e-159|563|pps:100994192|sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0046872//metal ion binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0046872//metal ion binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0046872//metal ion binding GO:0006974//cellular response to DNA damage stimulus;GO:0006915//apoptotic process;GO:0006996//organelle organization;GO:0022402//cell cycle process;GO:0009628//response to abiotic stimulus;GO:0000187//activation of MAPK activity;GO:0006974//cellular response to DNA damage stimulus;GO:0006915//apoptotic process;GO:0006996//organelle organization;GO:0022402//cell cycle process;GO:0009628//response to abiotic stimulus;GO:0000187//activation of MAPK activity;GO:0006974//cellular response to DNA damage stimulus;GO:0006915//apoptotic process;GO:0006996//organelle organization;GO:0022402//cell cycle process;GO:0009628//response to abiotic stimulus;GO:0000187//activation of MAPK activity gi|12746436|ref|NP_075544.1|/0/mitogen-activated protein kinase kinase kinase MLT isoform 1 [Mus musculus] 56249 2121 24.48666667 27.14333333 0.148601506 Up 0.328491105 Actr8 ARP8 actin-related protein 8 K11673|1|0.0|1226|mmu:56249|actin-related protein 8 GO:0000790//nuclear chromatin - "GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0000087//mitotic M phase;GO:0006351//transcription, DNA-templated" "gi|148692797|gb|EDL24744.1|/0/ARP8 actin-related protein 8 homolog (S. cerevisiae), partial [Mus musculus]" 17164 2884 199.9266667 182.4233333 -0.132180642 Down 0.328378277 Mapkapk2 MAP kinase-activated protein kinase 2 K04443|1|0.0|701|ngi:103725934|mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1] - - - - 14263 5196.59 3.26 3.963333333 0.281842345 Up 0.328378277 Fmo5 flavin containing monooxygenase 5 K00485|1|0.0|1078|mmu:14263|dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8] GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane "GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0000166//nucleotide binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0000166//nucleotide binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0000166//nucleotide binding" GO:0044710;GO:0044710;GO:0044710 gi|46559382|ref|NP_034362.2|/0/dimethylaniline monooxygenase [N-oxide-forming] 5 [Mus musculus] 269424 5486 4.006666667 3.303333333 -0.278479934 Down 0.328378277 Jade1 jade family PHD finger 1 K11347|1|0.0|1623|mmu:269424|protein Jade-1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding "GO:0043967//histone H4 acetylation;GO:0012501//programmed cell death;GO:0006351//transcription, DNA-templated;GO:0043967//histone H4 acetylation;GO:0012501//programmed cell death;GO:0006351//transcription, DNA-templated;GO:0043967//histone H4 acetylation;GO:0012501//programmed cell death;GO:0006351//transcription, DNA-templated;GO:0043967//histone H4 acetylation;GO:0012501//programmed cell death;GO:0006351//transcription, DNA-templated" gi|568921326|ref|XP_006500847.1|/0/PREDICTED: protein Jade-1 isoform X1 [Mus musculus] 67203 2219.52 24.21666667 26.86333333 0.149638035 Up 0.328378277 Nde1 nudE neurodevelopment protein 1 K16738|1|1e-167|592|mmu:67203|nuclear distribution protein NudE GO:0005815//microtubule organizing center;GO:0000922//spindle pole;GO:0032155;GO:0000776//kinetochore;GO:0005815//microtubule organizing center;GO:0000922//spindle pole;GO:0032155;GO:0000776//kinetochore;GO:0005815//microtubule organizing center;GO:0000922//spindle pole;GO:0032155;GO:0000776//kinetochore;GO:0005815//microtubule organizing center;GO:0000922//spindle pole;GO:0032155;GO:0000776//kinetochore GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0051648//vesicle localization;GO:0016477//cell migration;GO:0021543//pallium development;GO:0050000//chromosome localization;GO:0040001//establishment of mitotic spindle localization;GO:0000087//mitotic M phase;GO:0007098//centrosome cycle;GO:0048699//generation of neurons;GO:0051648//vesicle localization;GO:0016477//cell migration;GO:0021543//pallium development;GO:0050000//chromosome localization;GO:0040001//establishment of mitotic spindle localization;GO:0000087//mitotic M phase;GO:0007098//centrosome cycle;GO:0048699//generation of neurons;GO:0051648//vesicle localization;GO:0016477//cell migration;GO:0021543//pallium development;GO:0050000//chromosome localization;GO:0040001//establishment of mitotic spindle localization;GO:0000087//mitotic M phase;GO:0007098//centrosome cycle;GO:0048699//generation of neurons;GO:0051648//vesicle localization;GO:0016477//cell migration;GO:0021543//pallium development;GO:0050000//chromosome localization;GO:0040001//establishment of mitotic spindle localization;GO:0000087//mitotic M phase;GO:0007098//centrosome cycle;GO:0048699//generation of neurons gi|837808547|ref|XP_012782912.1|/4.21509e-120/PREDICTED: nuclear distribution protein nudE homolog 1 [Ochotona princeps] 69183 1211 2.98 2.376666667 -0.326372755 Down 0.328359472 C1qtnf2 C1q and tumor necrosis factor related protein 2 K07296|1|1e-25|119|gja:107110535|adiponectin GO:0044421 GO:0005515//protein binding GO:0051291//protein heterooligomerization;GO:0010828//positive regulation of glucose transport;GO:0019395//fatty acid oxidation;GO:0005978//glycogen biosynthetic process gi|58037153|ref|NP_081255.1|/8.72391e-99/complement C1q tumor necrosis factor-related protein 2 precursor [Mus musculus] 68774 1401 3.86 4.613333333 0.25720869 Up 0.328218436 Ms4a6d "membrane-spanning 4-domains, subfamily A, member 6D" "K08090|1|2e-10|69.7|phd:102315285|membrane-spanning 4-domains, subfamily A, member 2" GO:0031224//intrinsic component of membrane - - gi|13386172|ref|NP_081111.1|/5.49752e-111/membrane-spanning 4-domains subfamily A member 6D [Mus musculus] 213435 2975.38 174.0566667 191.0233333 0.1341918 Up 0.328199631 Mylk3 myosin light chain kinase 3 K00907|1|0.0|1235|mmu:213435|myosin-light-chain kinase [EC:2.7.11.18] GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity GO:0002526//acute inflammatory response;GO:0045214//sarcomere organization;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0070555//response to interleukin-1;GO:0002526//acute inflammatory response;GO:0045214//sarcomere organization;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0070555//response to interleukin-1 gi|662236774|ref|NP_001284541.1|/0/myosin light chain kinase 3 isoform 2 [Mus musculus] 22221 3817.21 15.03666667 13.40333333 -0.16589295 Down 0.328133815 Ubp1 upstream binding protein 1 K09275|1|0.0|959|mmu:22221|transcription factor CP2 and related proteins GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|134032032|ref|NP_001076788.1|/0/upstream-binding protein 1 isoform a [Mus musculus] 71891 2270.62 13.47333333 15.10666667 0.165078539 Up 0.328133815 Cdadc1 cytidine and dCMP deaminase domain containing 1 K01493|1|2e-08|63.5|phu:Phum_PHUM008070|dCMP deaminase [EC:3.5.4.12] - GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding - "gi|148704183|gb|EDL36130.1|/0/mCG13855, isoform CRA_f, partial [Mus musculus]" 70503 2987.57 12.29 10.87666667 -0.176248429 Down 0.328124412 Ddo D-aspartate oxidase K00272|1|1e-50|130|mmu:70503|D-aspartate oxidase [EC:1.4.3.1] GO:0042579//microbody GO:0005515//protein binding;GO:0015922//aspartate oxidase activity GO:0007620//copulation;GO:0044708//single-organism behavior;GO:0046416//D-amino acid metabolic process;GO:0006531//aspartate metabolic process "gi|148673010|gb|EDL04957.1|/0/D-aspartate oxidase, isoform CRA_a, partial [Mus musculus]" 68975 1328.51 10.61666667 12.02333333 0.179506051 Up 0.328124412 Med27 mediator complex subunit 27 K15170|1|4e-108|393|mmu:68975|mediator of RNA polymerase II transcription subunit 27 GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0003712//transcription cofactor activity;GO:0003712//transcription cofactor activity;GO:0003712//transcription cofactor activity GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter;GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter;GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter gi|76253678|ref|NP_081172.2|/2.89669e-107/mediator of RNA polymerase II transcription subunit 27 isoform a [Mus musculus] 223665 1780.94 40.14333333 44.34666667 0.143665251 Up 0.328105608 C030006K11Rik RIKEN cDNA C030006K11 gene K10730|1|5e-09|65.5|oaa:100089365|ATP-dependent DNA helicase Q4 [EC:3.6.4.12] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|21735489|ref|NP_663447.1|/8.30474e-118/UPF0598 protein C8orf82 homolog isoform 1 [Mus musculus] 19073 938 40.78333333 44.98333333 0.141410875 Up 0.328105608 Srgn serglycin K06849|1|6e-72|273|mmu:19073|proteoglycan peptide core protein GO:0005764//lysosome;GO:0030141//secretory granule;GO:0012505//endomembrane system;GO:0044421 GO:0005515//protein binding GO:0012501//programmed cell death;GO:0009888//tissue development;GO:0030279//negative regulation of ossification;GO:0050663//cytokine secretion;GO:0051604//protein maturation;GO:0033368//protease localization to mast cell secretory granule;GO:0033379 "gi|148700146|gb|EDL32093.1|/9.63757e-78/proteoglycan 1, secretory granule, isoform CRA_b [Mus musculus]" 12039 1773 178.2 194.72 0.127903736 Up 0.328067998 Bckdha "branched chain ketoacid dehydrogenase E1, alpha polypeptide" K00166|1|0.0|832|mmu:12039|2-oxoisovalerate dehydrogenase E1 component alpha subunit [EC:1.2.4.4] GO:0043231//intracellular membrane-bounded organelle;GO:0045240 "GO:0043169//cation binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0005515//protein binding" GO:0046683//response to organophosphorus;GO:0031667//response to nutrient levels;GO:0031960//response to corticosteroid;GO:0009063//cellular amino acid catabolic process "gi|183396774|ref|NP_031559.3|/0/2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial [Mus musculus]" 435791 549 0.196666667 0.013333333 -3.882643049 Down 0.328049193 Gm13271 predicted gene 13271 K05414|1|4e-37|155|cge:100763520|interferon alpha - - - - 20363 2030 175.29 191.71 0.129181898 Up 0.328030389 Sepp1 "selenoprotein P, plasma, 1" - - - - - 74492 2969 0.546666667 0.916666667 0.745735804 Up 0.328020986 Kbtbd13 kelch repeat and BTB (POZ) domain containing 13 K10476|1|6e-29|132|bfo:BRAFLDRAFT_219473|kelch repeat and BTB domain-containing protein 11 - - - - 66263 1620 2.876666667 3.53 0.295270125 Up 0.328011584 1810014B01Rik RIKEN cDNA 1810014B01 gene - - - - - 26943 3694 170.12 186.2466667 0.130661845 Up 0.327936365 Serinc3 serine incorporator 3 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0015179//L-amino acid transmembrane transporter activity GO:0012502//induction of programmed cell death;GO:0006575//cellular modified amino acid metabolic process;GO:0006643//membrane lipid metabolic process;GO:0043085//positive regulation of catalytic activity;GO:0015807//L-amino acid transport gi|213385301|ref|NP_036162.3|/0/serine incorporator 3 precursor [Mus musculus] 12237 2096 17.35666667 19.36666667 0.158085757 Up 0.327842341 Bub3 BUB3 mitotic checkpoint protein K02180|1|0.0|681|pale:102882717|cell cycle arrest protein BUB3 - - - - 76568 3337 5.236666667 6.126666667 0.226453586 Up 0.327823536 Ift46 intraflagellar transport 46 K19682|1|3e-146|522|mmu:76568|intraflagellar transport protein 46 - - - - 76252 1849 10.18 8.946666667 -0.186315391 Down 0.32772011 Atp6v0e2 "ATPase, H+ transporting, lysosomal V0 subunit E2" K02153|1|4e-52|188|cge:100766003|V-type H+-transporting ATPase subunit e - - - gi|537137011|gb|ERE66864.1|/3.73485e-51/V-type proton ATPase subunit e 2-like protein [Cricetulus griseus] 381062 2513 3.05 3.716666667 0.285200062 Up 0.327663696 Ermard ER membrane associated RNA degradation - - - - gi|183074530|ref|NP_001034641.2|/0/uncharacterized protein LOC381062 isoform 1 [Mus musculus] 67636 1417.7 26.03333333 23.43666667 -0.151592654 Down 0.327644891 Lyrm5 LYR motif containing 5 K20301|1|6e-09|65.1|soc:105200809|trafficking protein particle complex subunit 2;K10591|3|4e-06|55.5|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|19526856|ref|NP_598449.1|/4.50628e-41/LYR motif-containing protein 5 [Mus musculus] 104362 763 1.063333333 0.673333333 -0.659201131 Down 0.327588476 Meig1 meiosis expressed gene 1 - GO:0043231//intracellular membrane-bounded organelle - GO:0022403;GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|655859870|ref|XP_008266543.1|/2.59312e-42/PREDICTED: meiosis expressed gene 1 protein homolog isoform X1 [Oryctolagus cuniculus] 56844 1379.54 7.656666667 8.776666667 0.196956665 Up 0.327560269 Tssc4 tumor-suppressing subchromosomal transferable fragment 4 - - - - gi|9938004|ref|NP_064681.1|/9.91492e-142/protein TSSC4 isoform 1 [Mus musculus] 21855 1703 17.50333333 19.49666667 0.155597793 Up 0.327456843 Timm17b translocase of inner mitochondrial membrane 17b K17795|1|1e-70|270|mmu:21855|mitochondrial import inner membrane translocase subunit TIM17 - - - - 77710 1188 0.336666667 0.666666667 0.985644707 Up 0.327438038 4831407H17Rik RIKEN cDNA 4831407H17 gene - - - - - 56554 1287 0.01 0.18 4.169925001 Up 0.327409831 Raet1d retinoic acid early transcript delta K07987|1|4e-120|433|mmu:56554|retinoic acid early transcript 1 GO:0046658//anchored component of plasma membrane;GO:0009986//cell surface GO:0005102//receptor binding GO:0032496//response to lipopolysaccharide;GO:0030101//natural killer cell activation;GO:0006809//nitric oxide biosynthetic process;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0001819//positive regulation of cytokine production;GO:0002696//positive regulation of leukocyte activation;GO:0043330//response to exogenous dsRNA gi|9910522|ref|NP_064414.1|/3.71244e-119/retinoic acid early-inducible protein 1-delta precursor [Mus musculus] 14924 7350.05 2.746666667 2.166666667 -0.342204619 Down 0.327409831 Magi1 "membrane associated guanylate kinase, WW and PDZ domain containing 1" K05631|1|0.0|1909|mmu:14924|atrophin-1 interacting protein 3 (BAI1-associated protein 1) GO:0043296//apical junction complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043296//apical junction complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043296//apical junction complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043296//apical junction complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043296//apical junction complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043296//apical junction complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0042805//actinin binding;GO:0032550;GO:0042805//actinin binding;GO:0032550;GO:0042805//actinin binding;GO:0032550;GO:0042805//actinin binding;GO:0032550;GO:0042805//actinin binding;GO:0032550;GO:0042805//actinin binding;GO:0032550 - gi|74202844|dbj|BAE37498.1|/0/unnamed protein product [Mus musculus] 110168 1334 0.01 0.18 4.169925001 Up 0.327409831 Gpr18 G protein-coupled receptor 18 K08410|1|7e-161|569|mmu:110168|G protein-coupled receptor 18 GO:0031224//intrinsic component of membrane GO:0001608 GO:0035588 gi|33413406|ref|NP_877958.1|/5.98152e-160/N-arachidonyl glycine receptor [Mus musculus] 12047 796 0.01 0.18 4.169925001 Up 0.327409831 Bcl2a1d B cell leukemia/lymphoma 2 related protein A1d K02162|1|2e-95|350|mmu:12047|hematopoietic Bcl-2-related protein A1 GO:0044424 GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0004869//cysteine-type endopeptidase inhibitor activity GO:0030098//lymphocyte differentiation;GO:0006915//apoptotic process;GO:0050851//antigen receptor-mediated signaling pathway gi|6671630|ref|NP_031562.1|/1.42051e-94/B cell leukemia/lymphoma 2 related protein A1d [Mus musculus] 100043123 812 0.183333333 0.01 -4.196397213 Down 0.327409831 Gm11710 CD300 molecule like family member D4 K20395|1|2e-96|354|mmu:100043125|CO300B/D/F antigen GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part - GO:0002573//myeloid leukocyte differentiation gi|568970929|ref|XP_006531942.1|/1.19343e-95/PREDICTED: predicted gene 11710 isoform X1 [Mus musculus] 545490 1335 0.183333333 0.01 -4.196397213 Down 0.327409831 6230416C02Rik zinc finger protein 973 K09228|1|0.0|655|mmu:100043915|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|294345440|ref|NP_001170877.1|/0/KRAB box and zinc finger C2H2 type domain containing protein isoform 1 [Mus musculus] 97836 589 0.01 0.18 4.169925001 Up 0.327409831 C87198 expressed sequence C87198 - - - - - 107448 3837 0.616666667 1 0.69743723 Up 0.327372222 Unc5a unc-5 netrin receptor A K07521|1|0.0|1722|rno:60629|netrin receptor unc-5 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0007166//cell surface receptor signaling pathway;GO:0007411//axon guidance;GO:0012501//programmed cell death;GO:0006935//chemotaxis;GO:0006915//apoptotic process;GO:0007154//cell communication "gi|148709219|gb|EDL41165.1|/0/unc-5 homolog A (C. elegans), isoform CRA_b, partial [Mus musculus]" 66274 5053 5.626666667 6.563333333 0.222148207 Up 0.327297003 Lyrm9 LYR motif containing 9 - - - - - 628431 1447 0.93 0.556666667 -0.740417019 Down 0.327297003 Hmgb1-rs17 "high mobility group box 1, related sequence 17" K10802|1|5e-73|277|rro:104654245|high mobility group protein B1 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0005694//chromosome;GO:0044421 GO:0008289//lipid binding;GO:0005102//receptor binding;GO:0008134//transcription factor binding;GO:0019843//rRNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005539//glycosaminoglycan binding;GO:0033218//amide binding;GO:0000400//four-way junction DNA binding;GO:0019887//protein kinase regulator activity GO:0006954//inflammatory response;GO:0006284//base-excision repair;GO:0001932//regulation of protein phosphorylation;GO:0070555//response to interleukin-1;GO:0045445//myoblast differentiation;GO:0008284//positive regulation of cell proliferation;GO:0043434//response to peptide hormone;GO:0032989;GO:0007423//sensory organ development;GO:0002562;GO:0031960//response to corticosteroid;GO:0042742//defense response to bacterium;GO:0030595//leukocyte chemotaxis;GO:0002274;GO:0030099//myeloid cell differentiation;GO:0010975//regulation of neuron projection development;GO:0000278//mitotic cell cycle;GO:0071103//DNA conformation change;GO:0002237//response to molecule of bacterial origin;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006260//DNA replication;GO:0048511//rhythmic process;GO:0005980//glycogen catabolic process;GO:0051099//positive regulation of binding;GO:0009746;GO:0030036//actin cytoskeleton organization;GO:0030323//respiratory tube development;GO:0014909//smooth muscle cell migration;GO:0016568//chromatin modification;GO:0033028//myeloid cell apoptotic process;GO:0050927//positive regulation of positive chemotaxis "gi|148673911|gb|EDL05858.1|/7.0834e-85/mCG144566, partial [Mus musculus]" 66787 2787 2.686666667 3.32 0.305365904 Up 0.327240588 Gskip GSK3B interacting protein K12567|1|2e-06|38.9|rro:104677536|titin [EC:2.7.11.1] GO:0044424 - - gi|115292450|ref|NP_848728.2|/1.78575e-75/GSK3-beta interaction protein [Mus musculus] 67374 4822 40.44666667 44.48333333 0.137244089 Up 0.327212381 Jam2 junction adhesion molecule 2 K06735|1|6e-149|531|mmu:67374|junctional adhesion molecule 2 GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex GO:0046983//protein dimerization activity GO:0007155//cell adhesion gi|148747504|ref|NP_076333.3|/4.98304e-148/junctional adhesion molecule B precursor [Mus musculus] 140792 3322 10.54666667 11.94 0.179015738 Up 0.327165369 Colec12 collectin sub-family member 12 K10062|1|0.0|782|mmu:140792|collectin sub-family member 12 GO:0031224//intrinsic component of membrane;GO:0005578//proteinaceous extracellular matrix GO:0071813//lipoprotein particle binding;GO:0043169//cation binding;GO:0048029//monosaccharide binding;GO:0038024//cargo receptor activity;GO:0038023//signaling receptor activity GO:0051259//protein oligomerization;GO:0006909//phagocytosis;GO:0002758//innate immune response-activating signal transduction gi|165932373|ref|NP_569716.2|/0/collectin-12 [Mus musculus] 75692 1184.91 8.82 10.04333333 0.187387611 Up 0.327137162 Nr2c2ap nuclear receptor 2C2-associated protein - GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0022610;GO:0006366//transcription from RNA polymerase II promoter;GO:0022610 "gi|148696836|gb|EDL28783.1|/2.81728e-66/RIKEN cDNA 2310073E15, isoform CRA_b, partial [Mus musculus]" 100503676 1174 0.886666667 1.303333333 0.555742362 Up 0.327099552 Gm38426 "predicted gene, 38426" K08789|1|1e-10|69.7|pale:102890833|microtubule-associated serine/threonine kinase [EC:2.7.11.1] - - - - 70510 1842.87 38.44333333 42.46 0.143370937 Up 0.327080748 Rnf167 ring finger protein 167 K15706|1|9e-176|619|mmu:70510|E3 ubiquitin-protein ligase RNF167 [EC:2.3.2.27] - - - - 195522 1674.96 23.72 26.27333333 0.147495239 Up 0.327043138 Zfp691 zinc finger protein 691 K09230|1|2e-68|262|oas:101108082|SCAN domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|225543083|ref|NP_898963.2|/1.93518e-172/zinc finger protein 691 [Mus musculus] 52575 1846 6.456666667 7.476666667 0.211605666 Up 0.327033736 Trmt10c tRNA methyltransferase 10C K17654|1|0.0|779|mmu:52575|mitochondrial ribonuclease P protein 1 [EC:2.1.1.-] GO:0031981//nuclear lumen GO:0016741 GO:0006399//tRNA metabolic process gi|21312876|ref|NP_083368.1|/0/mitochondrial ribonuclease P protein 1 precursor [Mus musculus] 19089 2074.24 39.89666667 43.89333333 0.13773362 Up 0.327005529 Prkcsh protein kinase C substrate 80K-H K08288|1|0.0|817|mmu:19089|protein kinase C substrate 80K-H - - - - 278304 4090 16.47333333 18.44333333 0.162966913 Up 0.326986724 Zfp385c zinc finger protein 385C - - - - gi|755538821|ref|XP_011247364.1|/5.07358e-154/PREDICTED: zinc finger protein 385C isoform X7 [Mus musculus] 381650 3673 1.85 2.393333333 0.371496073 Up 0.326864493 Thap6 THAP domain containing 6 K09228|1|8e-07|59.3|acs:103280963|KRAB domain-containing zinc finger protein GO:0005856//cytoskeleton GO:0097159//organic cyclic compound binding - gi|344239313|gb|EGV95416.1|/2.2121e-102/THAP domain-containing protein 6 [Cricetulus griseus] 240087 7372 2.416666667 1.873333333 -0.367410865 Down 0.326864493 Mdc1 mediator of DNA damage checkpoint 1 K10955|1|1e-26|126|myb:102241796|intestinal mucin-2 GO:0043232 GO:0019904//protein domain specific binding GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress gi|132626693|ref|NP_001010833.2|/0/mediator of DNA damage checkpoint protein 1 [Mus musculus] 107449 5867 6.106666667 5.223333333 -0.225414324 Down 0.326845688 Unc5b unc-5 netrin receptor B K07521|1|0.0|1841|mmu:107449|netrin receptor unc-5 GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0007411//axon guidance "gi|148700216|gb|EDL32163.1|/0/unc-5 homolog B (C. elegans), isoform CRA_a, partial [Mus musculus]" 107513 9306 5.17 6.05 0.226770862 Up 0.326845688 Ssr1 "signal sequence receptor, alpha" K13249|1|8e-110|402|mmu:107513|translocon-associated protein subunit alpha GO:0031224//intrinsic component of membrane - - gi|74227801|dbj|BAE35725.1|/6.97516e-109/unnamed protein product [Mus musculus] 27403 6607 4.51 3.77 -0.25856291 Down 0.326808079 Abca7 "ATP-binding cassette, sub-family A (ABC1), member 7" "K05645|1|0.0|4076|mmu:27403|ATP-binding cassette, subfamily A (ABC1), member 7" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0031090//organelle membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005319//lipid transporter activity GO:0015914//phospholipid transport;GO:0006897//endocytosis gi|15451840|ref|NP_038878.1|/0/ATP-binding cassette sub-family A member 7 [Mus musculus] 71902 8209 4.553333333 3.813333333 -0.255870432 Down 0.326808079 Cand1 cullin associated and neddylation disassociated 1 K17263|1|0.0|2244|mmu:71902|cullin-associated NEDD8-dissociated protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0000151//ubiquitin ligase complex GO:0008134//transcription factor binding GO:0048869//cellular developmental process;GO:0045898//regulation of RNA polymerase II transcriptional preinitiation complex assembly;GO:0044092//negative regulation of molecular function;GO:0032446//protein modification by small protein conjugation;GO:0043623//cellular protein complex assembly gi|37360114|dbj|BAC98035.1|/0/mKIAA0829 protein [Mus musculus] 66048 1353 40.2 44.17333333 0.135980201 Up 0.326808079 Emc6 ER membrane protein complex subunit 6 - GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane - - gi|731501285|ref|XP_003416890.2|/3.41349e-28/PREDICTED: ER membrane protein complex subunit 6 [Loxodonta africana] 52563 4134 7.356666667 8.463333333 0.202173765 Up 0.326808079 Cdc23 CDC23 cell division cycle 23 K03355|1|0.0|1108|mmu:52563|anaphase-promoting complex subunit 8 GO:0031981//nuclear lumen;GO:0000152//nuclear ubiquitin ligase complex;GO:0044444//cytoplasmic part GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0051318;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0000070//mitotic sister chromatid segregation gi|30387632|ref|NP_848124.1|/0/cell division cycle protein 23 homolog [Mus musculus] 74388 4799 14.1 12.50666667 -0.172997835 Down 0.326789274 Dpp8 dipeptidylpeptidase 8 K08655|1|0.0|1790|mmu:74388|dipeptidyl-peptidase 8 [EC:3.4.14.5] GO:0044424 GO:0008238//exopeptidase activity GO:0019538//protein metabolic process "gi|148694129|gb|EDL26076.1|/0/dipeptidylpeptidase 8, isoform CRA_a, partial [Mus musculus]" 66118 1064 23.52666667 26.06 0.147540155 Up 0.326723457 Sarnp SAP domain containing ribonucleoprotein K18732|1|7e-73|276|mmu:66118|SAP domain-containing ribonucleoprotein GO:0031981//nuclear lumen "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0019904//protein domain specific binding" GO:0006366//transcription from RNA polymerase II promoter gi|13384730|ref|NP_079640.1|/5.68591e-72/SAP domain-containing ribonucleoprotein [Mus musculus] 18004 5503 1.65 1.19 -0.471504451 Down 0.326638836 Nek1 NIMA (never in mitosis gene a)-related expressed kinase 1 K08857|1|0.0|2247|mmu:18004|NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] GO:0005813//centrosome;GO:0005813//centrosome;GO:0031981//nuclear lumen;GO:0005813//centrosome;GO:0005635//nuclear envelope;GO:0031981//nuclear lumen;GO:0005813//centrosome;GO:0005635//nuclear envelope GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity;GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity;GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity;GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity GO:0009314//response to radiation;GO:0010927;GO:0033554//cellular response to stress;GO:0000087//mitotic M phase;GO:0006796//phosphate-containing compound metabolic process;GO:0009314//response to radiation;GO:0010927;GO:0033554//cellular response to stress;GO:0000087//mitotic M phase;GO:0006796//phosphate-containing compound metabolic process;GO:0009314//response to radiation;GO:0010927;GO:0033554//cellular response to stress;GO:0000087//mitotic M phase;GO:0006796//phosphate-containing compound metabolic process;GO:0009314//response to radiation;GO:0010927;GO:0033554//cellular response to stress;GO:0000087//mitotic M phase;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process gi|50511169|dbj|BAD32570.1|/0/mKIAA1901 protein [Mus musculus] 231633 2132 1.203333333 1.663333333 0.467040978 Up 0.326638836 Tmem119 transmembrane protein 119 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0001503//ossification gi|22122697|ref|NP_666274.1|/9.46475e-119/transmembrane protein 119 precursor [Mus musculus] 76137 4368 24.84 22.32 -0.154328146 Down 0.326516605 Mcur1 mitochondrial calcium uniporter regulator 1 - GO:0031304//intrinsic component of mitochondrial inner membrane - GO:0051560//mitochondrial calcium ion homeostasis;GO:0070588//calcium ion transmembrane transport gi|148709050|gb|EDL40996.1|/1.49381e-135/mCG19428 [Mus musculus] 19231 1192 130.0833333 142.7266667 0.133818778 Up 0.326507202 Ptma prothymosin alpha K13784|1|6e-10|63.5|ocu:100357307|prothymosin alpha - - GO:0006915//apoptotic process gi|74195796|dbj|BAE30461.1|/7.83912e-28/unnamed protein product [Mus musculus] 106039 3034 38.19 42.12333333 0.141424685 Up 0.326507202 Gga1 "golgi associated, gamma adaptin ear containing, ARF binding protein 1" K12404|1|0.0|1045|mmu:106039|ADP-ribosylation factor-binding protein GGA GO:0030119//AP-type membrane coat adaptor complex;GO:0031090//organelle membrane;GO:0005794//Golgi apparatus GO:0005488//binding GO:0009896;GO:0015031//protein transport gi|22122347|ref|NP_666041.1|/0/ADP-ribosylation factor-binding protein GGA1 [Mus musculus] 26365 3250.79 9.81 8.6 -0.189916477 Down 0.326469593 Ceacam1 carcinoembryonic antigen-related cell adhesion molecule 1 K06499|1|7e-98|361|mmu:26365|carcinoembryonic antigen-related cell adhesion molecule GO:0016021//integral component of membrane;GO:0031090//organelle membrane;GO:0016021//integral component of membrane;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane GO:0019900//kinase binding;GO:0019900//kinase binding;GO:0019900//kinase binding;GO:0019900//kinase binding GO:0043405//regulation of MAP kinase activity;GO:0043405//regulation of MAP kinase activity;GO:0043405//regulation of MAP kinase activity;GO:0043405//regulation of MAP kinase activity gi|399117|sp|P31809.1|CEAM1_MOUSE/0/RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 1; AltName: Full=Biliary glycoprotein 1; Short=BGP-1; AltName: Full=Biliary glycoprotein D; AltName: Full=MHVR1; AltName: Full=Murine hepatitis virus receptor; Short=MHV-R; AltName: CD_antigen=CD66a; Flags: Precursor 76976 1540 0.35 0.676666667 0.9510904 Up 0.32646019 Arxes2 adipocyte-related X-chromosome expressed sequence 2 K12948|1|2e-97|358|mmu:76219|signal peptidase complex subunit 3 [EC:3.4.-.-] GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane GO:0016787//hydrolase activity GO:0030073//insulin secretion;GO:0015980//energy derivation by oxidation of organic compounds;GO:0006613//cotranslational protein targeting to membrane;GO:0016485//protein processing gi|21617845|ref|NP_083817.1|/1.49481e-96/signal peptidase complex subunit 3 [Mus musculus] 667373 2215 1.566666667 2.073333333 0.404253824 Up 0.326422581 Ifit1bl1 interferon induced protein with tetratricpeptide repeats 1B like 1 K14217|1|0.0|888|mmu:667373|interferon-induced protein with tetratricopeptide repeats 1 GO:0044424;GO:0044424 GO:0005488//binding;GO:0005488//binding GO:0019079//viral genome replication;GO:0051095;GO:0043393//regulation of protein binding;GO:0034340//response to type I interferon;GO:0050687//negative regulation of defense response to virus;GO:0043330//response to exogenous dsRNA;GO:0035455//response to interferon-alpha;GO:0035456//response to interferon-beta;GO:0019079//viral genome replication;GO:0051095;GO:0043393//regulation of protein binding;GO:0034340//response to type I interferon;GO:0050687//negative regulation of defense response to virus;GO:0043330//response to exogenous dsRNA;GO:0035455//response to interferon-alpha;GO:0035456//response to interferon-beta gi|160333500|ref|NP_001103987.1|/0/uncharacterized protein LOC667373 isoform 1 [Mus musculus] 229782 4027 2.136666667 1.623333333 -0.396402585 Down 0.326422581 Slc35a3 "solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3" "K15272|1|6e-173|611|mmu:229782|solute carrier family 35 (UDP-sugar transporter), member A1/2/3" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0015215//nucleotide transmembrane transporter activity;GO:0005402//cation:sugar symporter activity GO:0006862//nucleotide transport "gi|148680425|gb|EDL12372.1|/1.34823e-175/solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3, isoform CRA_b [Mus musculus]" 65116 1312 4.046666667 4.826666667 0.254293181 Up 0.326394374 Prrg2 proline-rich Gla (G-carboxyglutamic acid) polypeptide 2 K01320|1|1e-10|70.1|ecb:100067072|coagulation factor VII [EC:3.4.21.21];K01314|2|2e-10|69.7|xma:102224608|coagulation factor X [EC:3.4.21.6];K01321|4|2e-10|69.7|xla:100049721|coagulation factor IX (Christmas factor) [EC:3.4.21.22] GO:0031224//intrinsic component of membrane GO:0005488//binding - "gi|148690844|gb|EDL22791.1|/3.8394e-111/proline-rich Gla (G-carboxyglutamic acid) polypeptide 2, isoform CRA_b, partial [Mus musculus]" 76483 1790.65 23.42 25.93333333 0.147066579 Up 0.326356764 Lmf1 lipase maturation factor 1 K00858|1|2e-40|169|tgu:100220598|NAD+ kinase [EC:2.7.1.23] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane - GO:0051004;GO:0071830;GO:0006486//protein glycosylation;GO:0019218//regulation of steroid metabolic process;GO:0016482//cytosolic transport;GO:0010467//gene expression;GO:0015031//protein transport;GO:0051004;GO:0071830;GO:0006486//protein glycosylation;GO:0019218//regulation of steroid metabolic process;GO:0016482//cytosolic transport;GO:0010467//gene expression;GO:0015031//protein transport "gi|148690487|gb|EDL22434.1|/0/RIKEN cDNA 2400010G15, isoform CRA_c, partial [Mus musculus]" 319160 409 0.176666667 0.01 -4.142957954 Down 0.326196924 Hist1h4k "histone cluster 1, H4k" K11254|1|2e-36|152|cge:100760690|histone H4 - - - - 103505 1320 0.01 0.176666667 4.142957954 Up 0.326196924 BB019430 expressed sequence BB019430 - - - - gi|74221521|dbj|BAE21485.1|/5.1433e-47/unnamed protein product [Mus musculus] 12515 1620 0.01 0.176666667 4.142957954 Up 0.326196924 Cd69 CD69 antigen K06502|1|6e-106|387|mmu:12515|CD69 antigen - - - - 19782 275 0.01 0.176666667 4.142957954 Up 0.326196924 Rmrp RNA component of mitochondrial RNAase P - - - - - 223272 2357 3.346666667 2.71 -0.304432012 Down 0.326159314 Itgbl1 "integrin, beta-like 1" K06252|1|1e-28|130|cjc:100396269|tenascin - - - gi|187960095|ref|NP_663442.2|/0/integrin beta-like protein 1 precursor [Mus musculus] 57875 1916 23.05666667 25.55 0.148139335 Up 0.326112302 Angptl4 angiopoietin-like 4 K08767|1|0.0|782|mmu:57875|angiopoietin-like 4 GO:0031012//extracellular matrix;GO:0044421 GO:0030234//enzyme regulator activity GO:0048869//cellular developmental process;GO:0006629//lipid metabolic process;GO:0051259//protein oligomerization;GO:0044092//negative regulation of molecular function;GO:0051004;GO:0006915//apoptotic process;GO:0033554//cellular response to stress;GO:0055090//acylglycerol homeostasis gi|255308873|ref|NP_065606.2|/0/angiopoietin-related protein 4 precursor [Mus musculus] 68718 1783 22.51333333 25 0.151148416 Up 0.326112302 Rnf166 ring finger protein 166 K17044|1|5e-131|470|rno:365022|RING finger protein 166 GO:0044464 GO:0046914//transition metal ion binding - gi|50511320|ref|NP_001002279.1|/4.27427e-130/RING finger protein 166 [Rattus norvegicus] 68554 1370.82 12.7 14.26666667 0.167819799 Up 0.326018278 Cebpzos "CCAAT/enhancer binding protein (C/EBP), zeta, opposite strand" K14832|1|1e-14|62.0|mmu:12607|ribosome biogenesis protein MAK21 - - - gi|987930376|ref|XP_015414350.1|/2.63639e-29/PREDICTED: protein CEBPZOS-like isoform X1 [Myotis davidii] 110749 1913 0.36 0.69 0.938599455 Up 0.32590545 Chaf1b "chromatin assembly factor 1, subunit B (p60)" K10751|1|0.0|1048|mmu:110749|chromatin assembly factor 1 subunit B GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0005515//protein binding "GO:0033554//cellular response to stress;GO:0006334//nucleosome assembly;GO:0006351//transcription, DNA-templated" gi|21312470|ref|NP_082359.1|/0/chromatin assembly factor 1 subunit B [Mus musculus] 227723 9465.93 25.58666667 23.12 -0.146250813 Down 0.325839633 Prrc2b proline-rich coiled-coil 2B "K13219|1|2e-130|471|acs:100568202|splicing factor, proline- and glutamine-rich;K13171|2|1e-05|57.4|obi:106872131|serine/arginine repetitive matrix protein 1" - - - gi|227500365|ref|NP_001153106.1|/0/protein PRRC2B isoform 1 [Mus musculus] 83436 4992 10.15 11.51 0.181408106 Up 0.325783219 Plekha2 "pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2" "K12229|1|2e-10|71.6|hmg:101240856|dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide;K06082|4|1e-07|62.8|ssc:100511480|FERM, RhoGEF and pleckstrin domain protein 2;K18439|5|1e-07|62.4|aqu:100639879|Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1" GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0035091//phosphatidylinositol binding;GO:0019904//protein domain specific binding - "gi|148700894|gb|EDL32841.1|/0/pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2, isoform CRA_a, partial [Mus musculus]" 107527 1950 0.866666667 0.506666667 -0.7744403 Down 0.325726804 Il1rl2 interleukin 1 receptor-like 2 K05172|1|0.0|1134|mmu:107527|interleukin 1 receptor-like 2 GO:0031224//intrinsic component of membrane GO:0004908//interleukin-1 receptor activity GO:0006952//defense response;GO:0001819//positive regulation of cytokine production;GO:0030217//T cell differentiation;GO:0007166//cell surface receptor signaling pathway "gi|148682626|gb|EDL14573.1|/0/interleukin 1 receptor-like 2, isoform CRA_a, partial [Mus musculus]" 16504 5184 1.426666667 0.993333333 -0.522298466 Down 0.325689195 Kcnc3 "potassium voltage gated channel, Shaw-related subfamily, member 3" K04889|1|0.0|1047|mmu:16504|potassium voltage-gated channel Shaw-related subfamily C member 3 GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0033267;GO:0032589//neuron projection membrane;GO:0043025//neuronal cell body;GO:0045202//synapse;GO:0033267;GO:0032589//neuron projection membrane;GO:0043025//neuronal cell body GO:0005267//potassium channel activity GO:0007269//neurotransmitter secretion;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0007269//neurotransmitter secretion gi|595582357|ref|NP_001277611.1|/0/potassium voltage-gated channel subfamily C member 3 isoform 2 [Mus musculus] 15439 1365 1.41 0.98 -0.524841508 Down 0.325689195 Hp haptoglobin K16142|1|0.0|717|mmu:15439|haptoglobin GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044421 GO:0004175//endopeptidase activity;GO:0042802//identical protein binding GO:0043086//negative regulation of catalytic activity;GO:0002526//acute inflammatory response;GO:0010243//response to organonitrogen compound;GO:0000302//response to reactive oxygen species;GO:0033273//response to vitamin;GO:0010038//response to metal ion;GO:0009887//organ morphogenesis;GO:0048232//male gamete generation;GO:0008219//cell death;GO:0031960//response to corticosteroid;GO:0010212//response to ionizing radiation;GO:0010727//negative regulation of hydrogen peroxide metabolic process;GO:0002237//response to molecule of bacterial origin;GO:0019538//protein metabolic process gi|8850219|ref|NP_059066.1|/0/haptoglobin precursor [Mus musculus] 75623 1265 1.866666667 1.383333333 -0.432315491 Down 0.325651585 Tex30 testis expressed 30 - - - - "gi|148664478|gb|EDK96894.1|/3.14252e-147/mCG121453, isoform CRA_a, partial [Mus musculus]" 320479 2639.67 1.403333333 1.886666667 0.42698182 Up 0.325651585 C330024D21Rik RIKEN cDNA C330024D21 gene - - - - "gi|148705839|gb|EDL37786.1|/3.7439e-83/mCG144986, partial [Mus musculus]" 14863 1121 120.9066667 132.0566667 0.12726334 Up 0.32563278 Gstm2 "glutathione S-transferase, mu 2" K00799|1|7e-127|456|mmu:14863|glutathione S-transferase [EC:2.5.1.18] GO:0016020//membrane;GO:0005783//endoplasmic reticulum "GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0046983//protein dimerization activity;GO:0072341//modified amino acid binding;GO:0042802//identical protein binding" GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0006807//nitrogen compound metabolic process;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0006790//sulfur compound metabolic process;GO:0006805//xenobiotic metabolic process;GO:0044767//single-organism developmental process;GO:0033554//cellular response to stress;GO:0031000//response to caffeine;GO:0007606//sensory perception of chemical stimulus "gi|148669988|gb|EDL01935.1|/1.50202e-126/mCG4061, partial [Mus musculus]" 384783 4015 4.48 3.753333333 -0.255326311 Down 0.325613976 Irs2 insulin receptor substrate 2 K07187|1|0.0|1939|mmu:384783|insulin receptor substrate 2 GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0019902//phosphatase binding GO:0006006//glucose metabolic process;GO:0032868//response to insulin;GO:0005978//glycogen biosynthetic process;GO:0008284//positive regulation of cell proliferation;GO:0048017//inositol lipid-mediated signaling;GO:0048732//gland development;GO:0010828//positive regulation of glucose transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001783//B cell apoptotic process;GO:0007259//JAK-STAT cascade;GO:0016477//cell migration;GO:0010746;GO:0043549//regulation of kinase activity;GO:0030888//regulation of B cell proliferation;GO:0048878//chemical homeostasis;GO:0071417//cellular response to organonitrogen compound;GO:0007417//central nervous system development;GO:0009746;GO:0050796//regulation of insulin secretion;GO:0006635//fatty acid beta-oxidation "gi|148690106|gb|EDL22053.1|/0/mCG17323, partial [Mus musculus]" 66826 1817.26 22.03333333 24.48333333 0.152112219 Up 0.325538757 Taz tafazzin K13511|1|1e-155|552|rno:363521|monolysocardiolipin acyltransferase [EC:2.3.1.-] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0008374//O-acyltransferase activity;GO:0008374//O-acyltransferase activity;GO:0008374//O-acyltransferase activity;GO:0008374//O-acyltransferase activity;GO:0008374//O-acyltransferase activity GO:0048534//hematopoietic or lymphoid organ development;GO:0006941//striated muscle contraction;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0010257//NADH dehydrogenase complex assembly;GO:0007507//heart development;GO:0042773//ATP synthesis coupled electron transport;GO:0014706//striated muscle tissue development;GO:0007007//inner mitochondrial membrane organization;GO:0048534//hematopoietic or lymphoid organ development;GO:0006941//striated muscle contraction;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0010257//NADH dehydrogenase complex assembly;GO:0007507//heart development;GO:0042773//ATP synthesis coupled electron transport;GO:0014706//striated muscle tissue development;GO:0007007//inner mitochondrial membrane organization;GO:0048534//hematopoietic or lymphoid organ development;GO:0006941//striated muscle contraction;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0010257//NADH dehydrogenase complex assembly;GO:0007507//heart development;GO:0042773//ATP synthesis coupled electron transport;GO:0014706//striated muscle tissue development;GO:0007007//inner mitochondrial membrane organization;GO:0048534//hematopoietic or lymphoid organ development;GO:0006941//striated muscle contraction;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0010257//NADH dehydrogenase complex assembly;GO:0007507//heart development;GO:0042773//ATP synthesis coupled electron transport;GO:0014706//striated muscle tissue development;GO:0007007//inner mitochondrial membrane organization;GO:0048534//hematopoietic or lymphoid organ development;GO:0006941//striated muscle contraction;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0010257//NADH dehydrogenase complex assembly;GO:0007507//heart development;GO:0042773//ATP synthesis coupled electron transport;GO:0014706//striated muscle tissue development;GO:0007007//inner mitochondrial membrane organization "gi|148697883|gb|EDL29830.1|/1.6147e-156/tafazzin, isoform CRA_c, partial [Mus musculus]" 69269 828.14 22.29666667 24.74666667 0.150406165 Up 0.325538757 Scnm1 sodium channel modifier 1 - - GO:0043169//cation binding;GO:0043169//cation binding GO:0006396//RNA processing;GO:0006396//RNA processing gi|81878408|sp|Q8K136.1|SCNM1_MOUSE/1.68915e-105/RecName: Full=Sodium channel modifier 1 106639 1988 2.616666667 3.233333333 0.305292093 Up 0.32547294 Vmac vimentin-type intermediate filament associated coiled-coil protein - GO:0005882//intermediate filament;GO:0005882//intermediate filament - - gi|30725792|ref|NP_849257.1|/1.17016e-47/vimentin-type intermediate filament-associated coiled-coil protein isoform 1 [Mus musculus] 330953 3798 2.706666667 2.136666667 -0.341155371 Down 0.32547294 Hcn4 "hyperpolarization-activated, cyclic nucleotide-gated K+ 4" K04957|1|0.0|1503|mmu:330953|hyperpolarization activated cyclic nucleotide-gated potassium channel 4 GO:0033267;GO:0016020//membrane GO:0005488//binding;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0046873//metal ion transmembrane transporter activity;GO:0005221//intracellular cyclic nucleotide activated cation channel activity GO:0043009//chordate embryonic development;GO:0003012//muscle system process;GO:0007268//chemical synaptic transmission;GO:0003013//circulatory system process;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0044057 gi|124487125|ref|NP_001074661.1|/0/potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [Mus musculus] 74440 4507.15 13.80666667 12.25666667 -0.171798377 Down 0.325397721 Cmip c-Maf inducing protein K10276|1|6e-06|56.6|aec:105148346|F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0008289//lipid binding - gi|254028206|ref|NP_001156734.1|/0/C-Maf-inducing protein isoform 1 [Mus musculus] 27784 3464 4.08 4.853333333 0.250406798 Up 0.325322502 Commd8 COMM domain containing 8 "K09655|1|1e-33|148|sko:100370172|beta-1,4-N-acetylgalactosaminyltransferase 2 [EC:2.4.1.-];K17618|2|3e-10|70.5|cin:100175954|ubiquitin-like domain-containing CTD phosphatase 1 [EC:3.1.3.16]" - - - gi|30519913|ref|NP_848714.1|/7.80105e-100/COMM domain-containing protein 8 [Mus musculus] 277250 7112 7.443333333 6.446666667 -0.207395456 Down 0.325266087 Kdm3b KDM3B lysine (K)-specific demethylase 3B K15601|1|0.0|3234|mmu:277250|lysine-specific demethylase 3 [EC:1.14.11.-] GO:0031981//nuclear lumen "GO:0043169//cation binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" "GO:0044710;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" gi|124486935|ref|NP_001074725.1|/0/lysine-specific demethylase 3B [Mus musculus] 269513 2906 1.706666667 1.243333333 -0.45696818 Down 0.325153259 Nkain3 Na+/K+ transporting ATPase interacting 3 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|50054090|ref|NP_766575.2|/4.01859e-94/sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 isoform 2 precursor [Mus musculus] 71810 2549.26 22.21666667 24.63666667 0.149164698 Up 0.325049833 Ranbp3 RAN binding protein 3 K15304|1|0.0|747|mmu:71810|Ran-binding protein 3 GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0046332//SMAD binding;GO:0046332//SMAD binding;GO:0046332//SMAD binding;GO:0046332//SMAD binding GO:0045184//establishment of protein localization;GO:0006810//transport;GO:0045184//establishment of protein localization;GO:0006810//transport;GO:0045184//establishment of protein localization;GO:0006810//transport;GO:0045184//establishment of protein localization;GO:0006810//transport gi|357197128|ref|NP_001239395.1|/0/ran-binding protein 3 isoform 1 [Mus musculus] 21754 3620 22.43 24.84666667 0.147622698 Up 0.325049833 Tesk1 testis specific protein kinase 1 K08841|1|0.0|931|mmu:21754|testis-specific kinase 1 [EC:2.7.12.1] - GO:0043169//cation binding;GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0048232//male gamete generation gi|227116330|ref|NP_035701.3|/0/dual specificity testis-specific protein kinase 1 [Mus musculus] 331360 1277 0.34 0.09 -1.91753784 Down 0.324984016 Zf12 Zf12 pseudogene K09230|1|7e-118|273|bom:102275674|SCAN domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0008366//axon ensheathment;GO:0006351//transcription, DNA-templated" gi|555954254|ref|XP_005889295.1|/6.22248e-117/PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 24 [Bos mutus] 54214 7532 41.16333333 37.47333333 -0.1354955 Down 0.324974614 Golga4 "golgi autoantigen, golgin subfamily a, 4" K20283|1|0.0|3537|mmu:54214|golgin subfamily A member 4 GO:0043231//intracellular membrane-bounded organelle GO:0019899//enzyme binding GO:0006886//intracellular protein transport gi|20127150|ref|NP_061218.2|/0/golgin subfamily A member 4 [Mus musculus] 70681 2499 4.513333333 5.323333333 0.238136574 Up 0.324946406 Fam175a "family with sequence similarity 175, member A" - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0043130//ubiquitin binding GO:0009314//response to radiation;GO:0006281//DNA repair;GO:0000077//DNA damage checkpoint;GO:0006325//chromatin organization "gi|148688324|gb|EDL20271.1|/0/coiled-coil domain containing 98, isoform CRA_e, partial [Mus musculus]" 18787 3024 36.55 40.22333333 0.138161237 Up 0.324824175 Serpine1 "serine (or cysteine) peptidase inhibitor, clade E, member 1" K03982|1|0.0|786|mmu:18787|plasminogen activator inhibitor 1 - - - gi|170172562|ref|NP_032897.2|/0/plasminogen activator inhibitor 1 precursor [Mus musculus] 210582 2507 106.9633333 117.1833333 0.131651063 Up 0.324824175 Coq10a coenzyme Q10A K18588|1|4e-107|391|mmu:210582|coenzyme Q-binding protein COQ10 - - - - 69430 1908 0.883333333 0.523333333 -0.755227801 Down 0.324814773 1700048O20Rik RIKEN cDNA 1700048O20 gene K09228|1|8e-07|58.2|myd:102767358|KRAB domain-containing zinc finger protein - - - - 50918 2884.65 115.4633333 105.2833333 -0.133157709 Down 0.324786566 Myadm myeloid-associated differentiation marker K00286|1|7e-42|175|bacu:103012704|pyrroline-5-carboxylate reductase [EC:1.5.1.2] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148699227|gb|EDL31174.1|/1.2084e-178/myeloid-associated differentiation marker, isoform CRA_b, partial [Mus musculus]" 71795 6350 12.12333333 13.66666667 0.172874984 Up 0.324777163 Pitpnc1 "phosphatidylinositol transfer protein, cytoplasmic 1" - GO:0043231//intracellular membrane-bounded organelle GO:0005548//phospholipid transporter activity;GO:0005488//binding GO:0006869//lipid transport;GO:0007154//cell communication;GO:0006650//glycerophospholipid metabolic process gi|351710336|gb|EHB13255.1|/6.40183e-174/Cytoplasmic phosphatidylinositol transfer protein 1 [Heterocephalus glaber] 73830 865.17 106.5066667 116.6033333 0.130665294 Up 0.324730152 Eif3k "eukaryotic translation initiation factor 3, subunit K" K15028|1|2e-123|443|mmu:73830|translation initiation factor 3 subunit K GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle "GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, RNA binding;GO:0008135//translation factor activity, RNA binding;GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, RNA binding;GO:0043021//ribonucleoprotein complex binding" GO:0006413//translational initiation;GO:0006413//translational initiation;GO:0006413//translational initiation "gi|148692149|gb|EDL24096.1|/1.656e-113/eukaryotic translation initiation factor 3, subunit 12, isoform CRA_a, partial [Mus musculus]" 20704 1374 0.093333333 0.346666667 1.893084796 Up 0.324730152 Serpina1e "serine (or cysteine) peptidase inhibitor, clade A, member 1E" K03984|1|0.0|790|mmu:20704|alpha-1-antitrypsin - - - gi|74138950|dbj|BAE27272.1|/0/unnamed protein product [Mus musculus] 116848 8369 8.33 7.253333333 -0.199672345 Down 0.324692542 Baz2a "bromodomain adjacent to zinc finger domain, 2A" K15224|1|0.0|3279|mmu:116848|bromodomain adjacent to zinc finger domain protein 2A - - - gi|114205435|ref|NP_473419.2|/0/bromodomain adjacent to zinc finger domain protein 2A [Mus musculus] 71911 3133 115.2766667 105.26 -0.131143224 Down 0.324664335 Bdh1 "3-hydroxybutyrate dehydrogenase, type 1" K00019|1|0.0|694|mmu:71911|3-hydroxybutyrate dehydrogenase [EC:1.1.1.30] GO:0031981//nuclear lumen;GO:0019866//organelle inner membrane;GO:0044429;GO:0031981//nuclear lumen;GO:0019866//organelle inner membrane;GO:0044429 "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0008289//lipid binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0008289//lipid binding" GO:0007417//central nervous system development;GO:0010038//response to metal ion;GO:0097305//response to alcohol;GO:0044710;GO:0043627//response to estrogen;GO:0031667//response to nutrient levels;GO:0044767//single-organism developmental process;GO:0043434//response to peptide hormone;GO:0051384//response to glucocorticoid;GO:0048513//animal organ development;GO:0006950//response to stress;GO:0007417//central nervous system development;GO:0010038//response to metal ion;GO:0097305//response to alcohol;GO:0044710;GO:0043627//response to estrogen;GO:0031667//response to nutrient levels;GO:0044767//single-organism developmental process;GO:0043434//response to peptide hormone;GO:0051384//response to glucocorticoid;GO:0048513//animal organ development;GO:0006950//response to stress "gi|170014720|ref|NP_780386.3|/0/D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor [Mus musculus]" 244152 2510.01 1 1.426666667 0.512648296 Up 0.324636128 Tsku "tsukushi, small leucine rich proteoglycan" K08130|1|0.0|709|mmu:244152|tsukushi (leucine-rich repeat-containing protein 54) - - - - 226041 7981 24.07333333 21.67333333 -0.151514864 Down 0.324626725 Pgm5 phosphoglucomutase 5 K15636|1|0.0|1071|mmu:226041|phosphoglucomutase-like protein 5 GO:0030054//cell junction;GO:0043232;GO:0044422;GO:0044444//cytoplasmic part;GO:0005886//plasma membrane GO:0046872//metal ion binding GO:0044723 gi|70608166|ref|NP_778178.3|/0/phosphoglucomutase-like protein 5 [Mus musculus] 23908 4811 1.74 2.263333333 0.379361768 Up 0.324617323 Hs2st1 heparan sulfate 2-O-sulfotransferase 1 K02513|1|0.0|699|mmu:23908|heparan sulfate 2-O-sulfotransferase HS2ST1 [EC:2.8.2.-] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system GO:0034483//heparan sulfate sulfotransferase activity GO:0001838//embryonic epithelial tube formation;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0006023 gi|170172560|ref|NP_035958.3|/0/heparan sulfate 2-O-sulfotransferase 1 [Mus musculus] 20479 3272 7.436666667 6.45 -0.205356947 Down 0.324579713 Vps4b vacuolar protein sorting 4B K12196|1|0.0|832|rno:360834|vacuolar protein-sorting-associated protein 4 GO:0000323//lytic vacuole;GO:0005770//late endosome;GO:0031090//organelle membrane GO:0032550;GO:0005515//protein binding;GO:0016887//ATPase activity GO:0032509//endosome transport via multivesicular body sorting pathway;GO:0030001//metal ion transport;GO:0010033//response to organic substance;GO:0006996//organelle organization;GO:0030301//cholesterol transport;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process gi|164698506|ref|NP_033216.2|/0/vacuolar protein sorting-associated protein 4B [Mus musculus] 225912 3220.67 5.676666667 6.59 0.215234436 Up 0.324504494 Cyb561a3 "cytochrome b561 family, member A3" K16295|1|3e-131|472|mmu:225912|cytochrome b ascorbate-dependent protein 3 GO:0005770//late endosome;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0005770//late endosome;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0005770//late endosome;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0005770//late endosome;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0003824//catalytic activity GO:0051234//establishment of localization;GO:0044710;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization;GO:0044710;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization;GO:0044710;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization;GO:0044710;GO:0006091//generation of precursor metabolites and energy "gi|148709421|gb|EDL41367.1|/4.37454e-140/cytochrome b, ascorbate dependent 3, isoform CRA_a, partial [Mus musculus]" 67968 1207 0.19 0.47 1.306661338 Up 0.324466885 Ooep oocyte expressed protein - GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding GO:0043009//chordate embryonic development;GO:0006464//cellular protein modification process;GO:0006461//protein complex assembly;GO:0019953//sexual reproduction;GO:0061245//establishment or maintenance of bipolar cell polarity gi|21312688|ref|NP_080756.1|/3.67659e-73/oocyte-expressed protein homolog [Mus musculus] 72139 1776 2.28 2.863333333 0.328661806 Up 0.324222423 2610044O15Rik8 RIKEN cDNA 2610044O15 gene K09228|1|2e-25|119|mmu:235956|KRAB domain-containing zinc finger protein - - - "gi|148679890|gb|EDL11837.1|/2.74024e-44/mCG1035771, isoform CRA_b [Mus musculus]" 100216534 77 3.593333333 4.313333333 0.263480439 Up 0.324184813 Snord96a "small nucleolar RNA, C/D box 96A" - - - - - 77558 1113 0.273333333 0.57 1.06030051 Up 0.324175411 9330179D12Rik RIKEN cDNA 9330179D12 gene - - - - "gi|148667441|gb|EDK99857.1|/5.42132e-28/mCG1037151, partial [Mus musculus]" 71878 2280 0.193333333 0.473333333 1.291766124 Up 0.324166008 Fam83d "family with sequence similarity 83, member D" K16805|1|0.0|1020|mmu:71878|protein FAM83D GO:0005856//cytoskeleton - GO:0000087//mitotic M phase "gi|148674335|gb|EDL06282.1|/0/mCG15735, partial [Mus musculus]" 27359 3059.21 0.826666667 0.473333333 -0.804449191 Down 0.324118997 Sytl4 synaptotagmin-like 4 K17598|1|0.0|865|mmu:27359|synaptotagmin-like protein GO:0031981//nuclear lumen;GO:0030133//transport vesicle;GO:0005815//microtubule organizing center;GO:0030141//secretory granule;GO:0044459;GO:0030136//clathrin-coated vesicle;GO:0005815//microtubule organizing center;GO:0030141//secretory granule;GO:0031981//nuclear lumen;GO:0030133//transport vesicle;GO:0044459;GO:0005815//microtubule organizing center;GO:0030141//secretory granule;GO:0031981//nuclear lumen;GO:0030133//transport vesicle;GO:0044459;GO:0005815//microtubule organizing center;GO:0030141//secretory granule;GO:0031981//nuclear lumen;GO:0030133//transport vesicle;GO:0044459 GO:0046914//transition metal ion binding;GO:0017016//Ras GTPase binding;GO:0008289//lipid binding;GO:0017016//Ras GTPase binding;GO:0046914//transition metal ion binding;GO:0008289//lipid binding;GO:0017016//Ras GTPase binding;GO:0046914//transition metal ion binding;GO:0008289//lipid binding;GO:0017016//Ras GTPase binding;GO:0046914//transition metal ion binding;GO:0008289//lipid binding GO:0009306//protein secretion;GO:0050796//regulation of insulin secretion;GO:0006887//exocytosis;GO:0050796//regulation of insulin secretion;GO:0009306//protein secretion;GO:0006887//exocytosis;GO:0050796//regulation of insulin secretion;GO:0009306//protein secretion;GO:0006887//exocytosis;GO:0050796//regulation of insulin secretion;GO:0009306//protein secretion;GO:0006887//exocytosis "gi|148688464|gb|EDL20411.1|/0/synaptotagmin-like 4, isoform CRA_a, partial [Mus musculus]" 107951 3389 8.376666667 9.543333333 0.188116999 Up 0.324071985 Cdk9 cyclin-dependent kinase 9 (CDC2-related kinase) K02211|1|0.0|757|chx:102188145|cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23] GO:0008023//transcription elongation factor complex;GO:0016604//nuclear body GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0000975//regulatory region DNA binding;GO:0003723//RNA binding "GO:0006351//transcription, DNA-templated;GO:0016570//histone modification;GO:0006796//phosphate-containing compound metabolic process;GO:0007050//cell cycle arrest;GO:0034097//response to cytokine;GO:0045005//DNA-dependent DNA replication maintenance of fidelity;GO:0006281//DNA repair" gi|589941671|ref|XP_006983557.1|/0/PREDICTED: cyclin-dependent kinase 9 [Peromyscus maniculatus bairdii] 170643 7284.5 2.946666667 2.353333333 -0.324378186 Down 0.324006168 Kirrel kin of IRRE like (Drosophila) K18273|1|2e-76|291|asn:102383405|alpha-tectorin;K14319|3|2e-30|139|bfo:BRAFLDRAFT_126584|Ran GTPase-activating protein 1;K17341|4|4e-26|124|ola:101172646|hemicentin GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0044459;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0044459;GO:0044444//cytoplasmic part GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0001932//regulation of protein phosphorylation;GO:0003008;GO:0030041//actin filament polymerization;GO:0007155//cell adhesion;GO:0001932//regulation of protein phosphorylation;GO:0003008;GO:0030041//actin filament polymerization;GO:0007155//cell adhesion gi|70608146|ref|NP_570937.2|/0/kin of IRRE-like protein 1 precursor [Mus musculus] 66889 2764 23.56666667 21.20666667 -0.152229843 Down 0.323996766 Rnf128 ring finger protein 128 K10629|1|0.0|854|mmu:66889|E3 ubiquitin-protein ligase RNF128 [EC:2.3.2.27] GO:0031224//intrinsic component of membrane;GO:0005768//endosome GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0010558;GO:0032446//protein modification by small protein conjugation "gi|148691965|gb|EDL23912.1|/0/ring finger protein 128, partial [Mus musculus]" 16371 2080 7.196666667 8.266666667 0.199976877 Up 0.323921547 Irx1 Iroquois related homeobox 1 (Drosophila) K19383|1|5e-09|65.9|soc:105204813|homeobox protein TGIF1;K19553|3|1e-07|60.8|xma:102238111|homeobox protein TGIF2 - - - gi|134288845|ref|NP_034703.2|/0/iroquois-class homeodomain protein IRX-1 [Mus musculus] 11515 7661.21 7.183333333 8.256666667 0.200905999 Up 0.323921547 Adcy9 adenylate cyclase 9 K08049|1|0.0|2468|mmu:11515|adenylate cyclase 9 [EC:4.6.1.1] GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane GO:0032550;GO:0043169//cation binding;GO:0016829//lyase activity;GO:0009975//cyclase activity;GO:0032550;GO:0043169//cation binding;GO:0016829//lyase activity;GO:0009975//cyclase activity GO:0045762//positive regulation of adenylate cyclase activity;GO:0007165//signal transduction;GO:0045762//positive regulation of adenylate cyclase activity;GO:0007165//signal transduction gi|150378487|ref|NP_033754.2|/0/adenylate cyclase type 9 isoform 1 [Mus musculus] 213211 2294 3.97 4.733333333 0.253717517 Up 0.323912144 Rnf26 ring finger protein 26 K15693|1|6e-177|623|mmu:213211|RING finger protein 26 GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding - gi|26328881|dbj|BAC28179.1|/5.41397e-176/unnamed protein product [Mus musculus] 56409 2171.13 99.21333333 108.2733333 0.126072042 Up 0.323827523 Nudt3 nudix (nucleotide diphosphate linked moiety X)-type motif 3 K07766|1|2e-51|206|mmu:56409|diphosphoinositol-polyphosphate diphosphatase [EC:3.6.1.52] GO:0044424 GO:0046872//metal ion binding;GO:0052842//inositol diphosphate pentakisphosphate diphosphatase activity;GO:0052841//inositol bisdiphosphate tetrakisphosphate diphosphatase activity;GO:0016462//pyrophosphatase activity GO:0009166//nucleotide catabolic process;GO:0071543//diphosphoinositol polyphosphate metabolic process;GO:0007154//cell communication;GO:0071543//diphosphoinositol polyphosphate metabolic process gi|597517975|ref|NP_001277975.1|/1.94224e-50/diphosphoinositol polyphosphate phosphohydrolase 1 isoform 2 [Mus musculus] 66358 1492 3.183333333 3.856666667 0.276816226 Up 0.323789913 Adprm "ADP-ribose/CDP-alcohol diphosphatase, manganese dependent" K01517|1|0.0|679|mmu:66358|manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [EC:3.6.1.13 3.6.1.16 3.6.1.53] - GO:0016462//pyrophosphatase activity;GO:0043169//cation binding - gi|160333181|ref|NP_079786.2|/0/manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [Mus musculus] 208595 1368 0.52 0.233333333 -1.156119202 Down 0.323733499 Mterf1b mitochondrial transcription termination factor 1b "K15031|1|0.0|685|mmu:208595|transcription termination factor, mitochondrial" GO:0005759//mitochondrial matrix GO:0043566//structure-specific DNA binding "GO:0000959//mitochondrial RNA metabolic process;GO:0071103//DNA conformation change;GO:0006351//transcription, DNA-templated" gi|295317344|ref|NP_001036135.2|/0/mitochondrial transcription termination factor-like [Mus musculus] 69603 718 1.9 1.416666667 -0.423499078 Down 0.323705292 2310020H05Rik RIKEN cDNA 2310020H05 gene - - - - - 16165 2163 0.473333333 0.196666667 -1.26710407 Down 0.323705292 Il13ra2 "interleukin 13 receptor, alpha 2" K05077|1|0.0|733|mmu:16165|interleukin 13 receptor alpha-2 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0009612//response to mechanical stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0009612//response to mechanical stimulus;GO:0007166//cell surface receptor signaling pathway gi|6680405|ref|NP_032382.1|/0/interleukin-13 receptor subunit alpha-2 isoform 1 precursor [Mus musculus] 67291 2760 2.546666667 3.156666667 0.309791787 Up 0.323705292 Ccdc137 coiled-coil domain containing 137 K11515|1|9e-06|55.5|nle:100601658|inner centromere protein - - - gi|22779893|ref|NP_690020.1|/4.58539e-116/coiled-coil domain-containing protein 137 [Mus musculus] 101055769 1280 1.416666667 1.893333333 0.418428088 Up 0.323705292 Gm12596 predicted gene 12596 - - - - "gi|148675219|gb|EDL07166.1|/7.6548e-16/mCG1028420, partial [Mus musculus]" 239652 3673 1.92 1.44 -0.415037499 Down 0.323705292 Zfp641 zinc finger protein 641 K09228|1|0.0|897|mmu:239652|KRAB domain-containing zinc finger protein - - - gi|30424631|ref|NP_776130.1|/0/zinc finger protein 641 [Mus musculus] 216892 3074.43 11.13666667 9.83 -0.18005416 Down 0.32362067 Spns2 spinster homolog 2 K20225|1|0.0|764|acs:103282837|capicua transcriptional repressor - - - - 21985 2276.52 6.22 7.196666667 0.210414257 Up 0.323573658 Tpd52 tumor protein D52 - - - - - 94245 1311 93.29333333 102.1 0.13013697 Up 0.323573658 Dtnbp1 dystrobrevin binding protein 1 K20189|1|2e-168|594|mmu:94245|dysbindin GO:0030659//cytoplasmic vesicle membrane;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0030424//axon;GO:0008021//synaptic vesicle;GO:0031082;GO:0005886//plasma membrane GO:0005488//binding GO:0007599//hemostasis;GO:0048753//pigment granule organization;GO:0010467//gene expression;GO:0007269//neurotransmitter secretion;GO:0010646//regulation of cell communication;GO:0007212//dopamine receptor signaling pathway;GO:0031175//neuron projection development;GO:0048513//animal organ development;GO:0048489//synaptic vesicle transport;GO:0033363//secretory granule organization;GO:0030036//actin cytoskeleton organization;GO:0048193//Golgi vesicle transport;GO:0008088//axo-dendritic transport gi|74198181|dbj|BAE35265.1|/1.05601e-177/unnamed protein product [Mus musculus] 28006 4305 7.063333333 6.086666667 -0.214696822 Down 0.323573658 Fam21 family with sequence similarity 21 K18462|1|0.0|2185|mmu:28006|WASH complex subunit FAM21 GO:0005769//early endosome;GO:0043234//protein complex - GO:0016192//vesicle-mediated transport "gi|148667139|gb|EDK99555.1|/0/DNA segment, Chr 6, Wayne State University 116, expressed, isoform CRA_d, partial [Mus musculus]" 75019 1630 0.2 0.48 1.263034406 Up 0.323526646 Rnase10 "ribonuclease, RNase A family, 10 (non-active)" K01172|1|4e-06|55.5|hgl:101710540|ribonuclease 6/7/8 [EC:3.1.27.-] - "GO:0016892//endoribonuclease activity, producing 3'-phosphomonoesters;GO:0097159//organic cyclic compound binding;GO:0016892//endoribonuclease activity, producing 3'-phosphomonoesters;GO:0097159//organic cyclic compound binding" - gi|247269231|ref|NP_083421.2|/9.414e-113/inactive ribonuclease-like protein 10 isoform 1 [Mus musculus] 78174 572 0.1 0.346666667 1.793549123 Up 0.323442025 Cox7b2 cytochrome c oxidase subunit VIIb2 K02271|1|3e-42|173|mmu:78174|cytochrome c oxidase subunit 7b GO:0005743//mitochondrial inner membrane;GO:0044425 - - gi|27229253|ref|NP_084328.1|/1.88056e-41/cytochrome c oxidase subunit VIIb2 [Mus musculus] 21648 791 23.05 20.71666667 -0.15397486 Down 0.323432623 Dynlt1b dynein light chain Tctex-type 1B K10420|1|1e-59|231|mmu:21648|dynein light chain Tctex-type 1 GO:0043231//intracellular membrane-bounded organelle;GO:0030286//dynein complex GO:0005515//protein binding;GO:0003774//motor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0031175//neuron projection development;GO:0006886//intracellular protein transport;GO:0040001//establishment of mitotic spindle localization;GO:0010721//negative regulation of cell development;GO:0019048//modulation by virus of host morphology or physiology;GO:0000087//mitotic M phase gi|6678265|ref|NP_033368.1|/9.54009e-59/dynein light chain Tctex-type 1 [Mus musculus] 626055 1547 5.376666667 6.28 0.224052526 Up 0.323404415 Gm15645 predicted gene 15645 K01581|1|2e-153|290|ngi:103747615|ornithine decarboxylase [EC:4.1.1.17] - - - gi|674081465|ref|XP_008848338.1|/1.84387e-152/PREDICTED: ornithine decarboxylase [Nannospalax galili] 78749 3321.8 6.273333333 5.37 -0.224310134 Down 0.323404415 Filip1l filamin A interacting protein 1-like K10402|1|4e-22|110|sko:100368346|kinesin family member 20;K20478|5|4e-22|110|dre:557772|golgin subfamily B member 1 - - - gi|295424207|ref|NP_001035487.2|/0/filamin A-interacting protein 1-like isoform 1 [Mus musculus] 76688 2590 15.83666667 17.66333333 0.157488921 Up 0.323357403 Arfrp1 ADP-ribosylation factor related protein 1 K07952|1|1e-94|237|cge:100762329|ADP-ribosylation factor related protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport;GO:0009154//purine ribonucleotide catabolic process;GO:0033365//protein localization to organelle;GO:0048598//embryonic morphogenesis;GO:0035556//intracellular signal transduction;GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport;GO:0009154//purine ribonucleotide catabolic process;GO:0033365//protein localization to organelle;GO:0048598//embryonic morphogenesis;GO:0035556//intracellular signal transduction;GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport;GO:0009154//purine ribonucleotide catabolic process;GO:0033365//protein localization to organelle;GO:0048598//embryonic morphogenesis;GO:0035556//intracellular signal transduction;GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport;GO:0009154//purine ribonucleotide catabolic process;GO:0033365//protein localization to organelle;GO:0048598//embryonic morphogenesis;GO:0035556//intracellular signal transduction "gi|148675460|gb|EDL07407.1|/1.24014e-115/ADP-ribosylation factor related protein 1, isoform CRA_b, partial [Mus musculus]" 15016 1181 17.63666667 15.80333333 -0.158349025 Down 0.323357403 H2-Q5 "histocompatibility 2, Q region locus 5" "K06751|1|6e-90|333|mmu:15018|major histocompatibility complex, class I" - - - - 16558 5446 9.61 8.45 -0.18558509 Down 0.323357403 Kif16b kinesin family member 16B K17916|1|0.0|2334|mmu:16558|kinesin family member 16B GO:0015630//microtubule cytoskeleton;GO:0005768//endosome GO:0032550;GO:0003777//microtubule motor activity;GO:0017016//Ras GTPase binding;GO:0043168//anion binding;GO:1901981//phosphatidylinositol phosphate binding GO:0009888//tissue development;GO:0007369//gastrulation;GO:0038127//ERBB signaling pathway;GO:0001881//receptor recycling;GO:0006928//movement of cell or subcellular component;GO:0009057//macromolecule catabolic process;GO:0006892//post-Golgi vesicle-mediated transport gi|124487287|ref|NP_001074602.1|/0/kinesin-like protein KIF16B [Mus musculus] 105298 2404 11.96 13.45666667 0.170103697 Up 0.323338599 Epdr1 ependymin related protein 1 (zebrafish) - GO:0000323//lytic vacuole GO:0046872//metal ion binding GO:0031589//cell-substrate adhesion gi|282165729|ref|NP_598826.3|/1.05624e-129/mammalian ependymin-related protein 1 precursor [Mus musculus] 69232 3260.99 23.29666667 20.97666667 -0.151338104 Down 0.323272782 Qrich1 glutamine-rich 1 - - - GO:0006915//apoptotic process;GO:0006915//apoptotic process gi|166295181|ref|NP_780352.2|/0/glutamine-rich protein 1 [Mus musculus] 76795 5266.03 24.13333333 21.81333333 -0.145816949 Down 0.323272782 Tbc1d9b "TBC1 domain family, member 9B" K19951|1|0.0|2276|mmu:76795|TBC1 domain family member 9 GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464 GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding - gi|124358940|ref|NP_084021.2|/0/TBC1 domain family member 9B isoform 3 [Mus musculus] 100929 3111.28 3.303333333 3.996666667 0.274874696 Up 0.323235172 Tyw1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) K15449|1|0.0|1466|mmu:100929|tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44] - GO:0046914//transition metal ion binding;GO:0032553//ribonucleotide binding;GO:0051536//iron-sulfur cluster binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0032553//ribonucleotide binding;GO:0051536//iron-sulfur cluster binding;GO:0003824//catalytic activity GO:0006399//tRNA metabolic process;GO:0044710;GO:0006399//tRNA metabolic process;GO:0044710 gi|30725740|ref|NP_849228.1|/0/S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase isoform 2 [Mus musculus] 70186 635 95.91333333 87.60333333 -0.130745619 Down 0.32302832 Fam162a "family with sequence similarity 162, member A" - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0001666//response to hypoxia;GO:0070997//neuron death;GO:0010822//positive regulation of mitochondrion organization gi|21312546|ref|NP_081618.1|/3.38616e-83/protein FAM162A [Mus musculus] 26383 3586 34.31333333 37.72333333 0.13668788 Up 0.322915491 Fto fat mass and obesity associated K19469|1|0.0|958|mmu:26383|alpha-ketoglutarate-dependent dioxygenase FTO [EC:1.14.11.-] GO:0043231//intracellular membrane-bounded organelle "GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0005506//iron ion binding" GO:0035513//oxidative RNA demethylation;GO:0006281//DNA repair;GO:0003016//respiratory system process;GO:0070343;GO:0035511//oxidative DNA demethylation;GO:0035264//multicellular organism growth;GO:0019915//lipid storage;GO:0048513//animal organ development;GO:0048871//multicellular organismal homeostasis gi|166851822|ref|NP_036066.2|/0/alpha-ketoglutarate-dependent dioxygenase FTO [Mus musculus] 229007 2088.75 13.18333333 11.69666667 -0.172617747 Down 0.322906089 Zgpat "zinc finger, CCCH-type with G patch domain" K13103|1|3e-09|66.6|tsp:Tsp_06173|tuftelin-interacting protein 11 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0006351//transcription, DNA-templated;GO:0007176//regulation of epidermal growth factor-activated receptor activity" "gi|148675464|gb|EDL07411.1|/0/zinc finger, CCCH-type with G patch domain, isoform CRA_a, partial [Mus musculus]" 67393 2311 12.17666667 13.67 0.16689399 Up 0.322906089 Cxxc5 CXXC finger 5 K03344|1|2e-33|146|cmk:103177732|Dvl-binding protein IDAX GO:0043231//intracellular membrane-bounded organelle GO:0060089;GO:0046914//transition metal ion binding GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|74215664|dbj|BAE21439.1|/8.55237e-129/unnamed protein product [Mus musculus] 103949 299 9.446666667 8.3 -0.186694016 Down 0.322765053 Rn7s2 7S RNA 2 K00109|1|5e-32|137|gja:107122496|2-hydroxyglutarate dehydrogenase [EC:1.1.99.2];K16503|2|2e-12|73.2|ocu:100359044|cadherin-related family member 3;K09534|3|8e-07|54.3|myb:102248172|DnaJ homolog subfamily C member 14 - - - - 103948 299 9.446666667 8.3 -0.186694016 Down 0.322765053 Rn7s1 7S RNA 1 K00109|1|5e-32|137|gja:107122496|2-hydroxyglutarate dehydrogenase [EC:1.1.99.2];K16503|2|2e-12|73.2|ocu:100359044|cadherin-related family member 3;K09534|3|8e-07|54.3|myb:102248172|DnaJ homolog subfamily C member 14 - - - - 223527 2429 7.066666667 6.096666667 -0.21300919 Down 0.322736846 Eny2 enhancer of yellow 2 homolog (Drosophila) K11368|1|2e-42|177|myd:102768190|enhancer of yellow 2 transcription factor GO:0070461//SAGA-type complex GO:0003713//transcription coactivator activity "GO:0050658//RNA transport;GO:0016570//histone modification;GO:0006351//transcription, DNA-templated" "gi|148676796|gb|EDL08743.1|/4.73586e-61/mCG145920, isoform CRA_b, partial [Mus musculus]" 30843 2050.16 4.04 4.793333333 0.246673977 Up 0.322736846 Fbxl12 F-box and leucine-rich repeat protein 12 K10278|1|0.0|661|mmu:30843|F-box and leucine-rich repeat protein 12 GO:0044424;GO:0043234//protein complex;GO:0044424;GO:0043234//protein complex;GO:0044424;GO:0043234//protein complex;GO:0044424;GO:0043234//protein complex GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process gi|557440839|ref|NP_001273458.1|/0/F-box/LRR-repeat protein 12 isoform c [Mus musculus] 12068 1492 3.963333333 4.716666667 0.251053338 Up 0.322736846 Bet1 Bet1 golgi vesicular membrane trafficking protein K08504|1|3e-50|202|rno:29631|blocked early in transport 1 - - - - 227333 5694 10.80666667 9.52 -0.182888111 Down 0.322718041 Dgkd "diacylglycerol kinase, delta" K00901|1|0.0|2282|mmu:227333|diacylglycerol kinase (ATP) [EC:2.7.1.107] GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0043169//cation binding;GO:0032550;GO:0042802//identical protein binding;GO:0008289//lipid binding;GO:0046983//protein dimerization activity;GO:0016301//kinase activity GO:0016192//vesicle-mediated transport;GO:0035556//intracellular signal transduction;GO:0001775//cell activation;GO:0051259//protein oligomerization;GO:0045184//establishment of protein localization;GO:0040007//growth;GO:0038127//ERBB signaling pathway;GO:0042221//response to chemical;GO:0007599//hemostasis;GO:0006639//acylglycerol metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0032502//developmental process gi|221139790|ref|NP_808314.2|/0/diacylglycerol kinase delta [Mus musculus] 320534 4583 4.946666667 5.783333333 0.225444571 Up 0.322699237 Tmem104 transmembrane protein 104 K01069|1|6e-36|156|ame:552568|hydroxyacylglutathione hydrolase [EC:3.1.2.6] GO:0031224//intrinsic component of membrane - - "gi|148702521|gb|EDL34468.1|/0/mCG6601, isoform CRA_c, partial [Mus musculus]" 12500 1330 0.976666667 0.603333333 -0.694910967 Down 0.322689834 Cd3d "CD3 antigen, delta polypeptide" K06450|1|1e-95|352|mmu:12500|T-cell surface glycoprotein CD3 delta chain GO:0031224//intrinsic component of membrane;GO:0042101//T cell receptor complex GO:0003712//transcription cofactor activity;GO:0046983//protein dimerization activity;GO:0038023//signaling receptor activity GO:0043368//positive T cell selection;GO:0007165//signal transduction;GO:0065003;GO:0006366//transcription from RNA polymerase II promoter gi|227498961|ref|NP_038515.3|/8.76962e-95/T-cell surface glycoprotein CD3 delta chain precursor [Mus musculus] 22183 4492 4.28 5.07 0.244374951 Up 0.322577006 Zrsr1 "zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1" K12836|1|5e-28|130|obi:106871304|splicing factor U2AF 35 kDa subunit;K00816|3|3e-27|127|smm:Smp_123750|kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64] GO:0005681//spliceosomal complex GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0036002//pre-mRNA binding "GO:0000398//mRNA splicing, via spliceosome" gi|6755917|ref|NP_035793.1|/1.80125e-160/U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1 [Mus musculus] 237928 1910 83.24 91.07666667 0.129804526 Up 0.322492384 Phospho1 "phosphatase, orphan 1" K06124|1|3e-155|551|mmu:237928|phosphoethanolamine/phosphocholine phosphatase [EC:3.1.3.75] - "GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;GO:0043169//cation binding;GO:0016791//phosphatase activity" GO:0030282//bone mineralization;GO:0006796//phosphate-containing compound metabolic process;GO:0036075;GO:0030278//regulation of ossification "gi|148684046|gb|EDL15993.1|/3.42764e-157/phosphatase, orphan 1, isoform CRA_a, partial [Mus musculus]" 102633773 1524 0.293333333 0.593333333 1.016301812 Up 0.32243597 Gm31520 sterol-C5-desaturase pseudogene K00227|1|6e-76|287|rno:114100|Delta7-sterol 5-desaturase [EC:1.14.19.20] - - - - 18046 1953.79 33.37666667 36.71333333 0.137464228 Up 0.322370153 Nfyc nuclear transcription factor-Y gamma "K08066|1|4e-76|273|myb:102256788|nuclear transcription factor Y, gamma" - - - gi|830013424|ref|XP_012578086.1|/8.42071e-71/PREDICTED: nuclear transcription factor Y subunit gamma isoform X1 [Condylura cristata] 12322 4268 17.01666667 15.22333333 -0.160664171 Down 0.322266727 Camk2a calcium/calmodulin-dependent protein kinase II alpha K04515|1|0.0|954|ssc:100626014|calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] GO:0031981//nuclear lumen;GO:0097060//synaptic membrane;GO:0030425//dendrite;GO:0030139//endocytic vesicle;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0097060//synaptic membrane;GO:0030425//dendrite;GO:0030139//endocytic vesicle;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0097060//synaptic membrane;GO:0030425//dendrite;GO:0030139//endocytic vesicle;GO:0043234//protein complex GO:0005102//receptor binding;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0005102//receptor binding;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0005102//receptor binding;GO:0032550;GO:0004674//protein serine/threonine kinase activity GO:0044772//mitotic cell cycle phase transition;GO:0007269//neurotransmitter secretion;GO:0048167//regulation of synaptic plasticity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0019221//cytokine-mediated signaling pathway;GO:0006468//protein phosphorylation;GO:0070838//divalent metal ion transport;GO:0007215//glutamate receptor signaling pathway;GO:0044772//mitotic cell cycle phase transition;GO:0007269//neurotransmitter secretion;GO:0048167//regulation of synaptic plasticity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0019221//cytokine-mediated signaling pathway;GO:0006468//protein phosphorylation;GO:0070838//divalent metal ion transport;GO:0007215//glutamate receptor signaling pathway;GO:0044772//mitotic cell cycle phase transition;GO:0007269//neurotransmitter secretion;GO:0048167//regulation of synaptic plasticity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0019221//cytokine-mediated signaling pathway;GO:0006468//protein phosphorylation;GO:0070838//divalent metal ion transport;GO:0007215//glutamate receptor signaling pathway gi|39104626|dbj|BAC65692.3|/0/mKIAA0968 protein [Mus musculus] 76789 2256 15.16 16.95333333 0.161299208 Up 0.322266727 Mzt1 mitotic spindle organizing protein 1 K18633|1|6e-25|118|rno:692032|mitotic-spindle organizing protein 1 GO:0000931//gamma-tubulin large complex - GO:0034629//cellular protein complex localization "gi|148668124|gb|EDL00454.1|/3.02479e-38/mCG1042562, partial [Mus musculus]" 22224 3745 15.56 17.35333333 0.157370751 Up 0.322266727 Usp10 ubiquitin specific peptidase 10 K11841|1|0.0|1516|mmu:22224|ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12] GO:0005856//cytoskeleton;GO:0005768//endosome;GO:0005856//cytoskeleton;GO:0005768//endosome GO:0016790//thiolester hydrolase activity;GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0019783//ubiquitin-like protein-specific protease activity GO:0006259//DNA metabolic process;GO:0019941//modification-dependent protein catabolic process;GO:0042770//signal transduction in response to DNA damage;GO:0070646//protein modification by small protein removal;GO:0006914//autophagy;GO:0006259//DNA metabolic process;GO:0019941//modification-dependent protein catabolic process;GO:0042770//signal transduction in response to DNA damage;GO:0070646//protein modification by small protein removal;GO:0006914//autophagy "gi|148679672|gb|EDL11619.1|/0/ubiquitin specific peptidase 10, isoform CRA_a, partial [Mus musculus]" 276919 3448 1.8 2.32 0.366127899 Up 0.322219715 Gemin4 gem (nuclear organelle) associated protein 4 K13132|1|0.0|2123|mmu:276919|gem associated protein 4 GO:0016604//nuclear body GO:0005488//binding - gi|262331526|ref|NP_796341.2|/0/gem-associated protein 4 [Mus musculus] 67538 2711 1.126666667 1.566666667 0.47563751 Up 0.322191508 Zswim3 zinc finger SWIM-type containing 3 K17604|1|0.0|1331|mmu:67538|zinc finger SWIM domain-containing protein 3 - GO:0046914//transition metal ion binding - gi|30410014|ref|NP_848462.1|/0/zinc finger SWIM domain-containing protein 3 [Mus musculus] 107869 1815 1.103333333 1.54 0.481061635 Up 0.322191508 Cth cystathionase (cystathionine gamma-lyase) K01758|1|0.0|771|mmu:107869|cystathionine gamma-lyase [EC:4.4.1.1] GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0016846//carbon-sulfur lyase activity;GO:0043168//anion binding GO:0008283//cell proliferation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0006534//cysteine metabolic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0018205//peptidyl-lysine modification;GO:0000097//sulfur amino acid biosynthetic process;GO:0016049//cell growth;GO:0051260//protein homooligomerization gi|22122387|ref|NP_666065.1|/0/cystathionine gamma-lyase [Mus musculus] 75788 5330.86 9.693333333 10.97333333 0.178937067 Up 0.322172703 Smurf1 SMAD specific E3 ubiquitin protein ligase 1 K04678|1|0.0|1486|rno:690516|E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26] - - - gi|87044886|ref|NP_083714.3|/0/E3 ubiquitin-protein ligase SMURF1 isoform 2 [Mus musculus] 110355 3379 32 35.31333333 0.142141103 Up 0.322163301 Adrbk1 "adrenergic receptor kinase, beta 1" K00910|1|0.0|1358|mmu:110355|beta-adrenergic-receptor kinase [EC:2.7.11.15] GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044444//cytoplasmic part GO:0032550;GO:0031753;GO:0031690//adrenergic receptor binding;GO:0004674//protein serine/threonine kinase activity;GO:0008289//lipid binding;GO:0032550;GO:0031753;GO:0031690//adrenergic receptor binding;GO:0004674//protein serine/threonine kinase activity;GO:0008289//lipid binding GO:0006941//striated muscle contraction;GO:0038127//ERBB signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0010863//positive regulation of phospholipase C activity;GO:0006468//protein phosphorylation;GO:0048522;GO:0044767//single-organism developmental process;GO:0003057//regulation of the force of heart contraction by chemical signal;GO:0006941//striated muscle contraction;GO:0038127//ERBB signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0010863//positive regulation of phospholipase C activity;GO:0006468//protein phosphorylation;GO:0048522;GO:0044767//single-organism developmental process;GO:0003057//regulation of the force of heart contraction by chemical signal gi|595763175|ref|NP_001277747.1|/0/beta-adrenergic receptor kinase 1 isoform 1 [Mus musculus] 105948585 886 0.44 0.166666667 -1.40053793 Down 0.322144496 Clcf1-pold4 Clcf1-pold4 readthrough K03505|1|8e-31|136|mmu:69745|DNA polymerase delta subunit 4 GO:0044464;GO:0043234//protein complex;GO:0044421;GO:0031981//nuclear lumen;GO:0042575 GO:0005126//cytokine receptor binding;GO:0046983//protein dimerization activity;GO:0016779//nucleotidyltransferase activity;GO:0005488//binding GO:0006954//inflammatory response;GO:0043524//negative regulation of neuron apoptotic process;GO:0030098//lymphocyte differentiation;GO:0045687//positive regulation of glial cell differentiation;GO:0046887//positive regulation of hormone secretion;GO:0043408//regulation of MAPK cascade;GO:0045830//positive regulation of isotype switching;GO:0030888//regulation of B cell proliferation;GO:0002828//regulation of type 2 immune response;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0006289//nucleotide-excision repair;GO:0000723//telomere maintenance;GO:0006261//DNA-dependent DNA replication;GO:0051320 gi|533139327|ref|XP_005384395.1|/8.78068e-38/PREDICTED: cardiotrophin-like cytokine factor 1 isoform X1 [Chinchilla lanigera] 68957 1689 0.543333333 0.25 -1.119909464 Down 0.322125691 Paqr6 progestin and adipoQ receptor family member VI K17387|1|4e-55|218|gfr:102034408|kinesin family member 23;K07297|3|6e-11|71.6|lcm:102350151|adiponectin receptor GO:0031224//intrinsic component of membrane - - gi|755504373|ref|XP_011238519.1|/0/PREDICTED: progestin and adipoQ receptor family member 6 isoform X3 [Mus musculus] 94230 4513 16.48666667 14.70666667 -0.164829449 Down 0.322031667 Cpsf1 cleavage and polyadenylation specific factor 1 K14401|1|0.0|2811|mmu:94230|cleavage and polyadenylation specificity factor subunit 1 GO:0005849//mRNA cleavage factor complex;GO:0005849//mRNA cleavage factor complex GO:0003729//mRNA binding;GO:0003729//mRNA binding GO:0031124//mRNA 3'-end processing;GO:0031124//mRNA 3'-end processing gi|16751835|ref|NP_444423.1|/0/cleavage and polyadenylation specificity factor subunit 1 isoform 2 [Mus musculus] 232023 2906 7.163333333 8.206666667 0.196165279 Up 0.321918839 Vopp1 "vesicular, overexpressed in cancer, prosurvival protein 1" - GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0012506//vesicle membrane GO:0060089 "GO:0006351//transcription, DNA-templated;GO:0007154//cell communication" "gi|22122699|ref|NP_666280.1|/4.04665e-70/vesicular, overexpressed in cancer, prosurvival protein 1 precursor [Mus musculus]" 66549 3262 6.203333333 7.16 0.206915938 Up 0.321862424 Aggf1 angiogenic factor with G patch and FHA domains 1 K13094|1|3e-06|57.4|cqu:CpipJ_CPIJ009279|RNA-binding protein 5/10 GO:0044444//cytoplasmic part GO:0097159//organic cyclic compound binding GO:0001525//angiogenesis;GO:0022610;GO:0001935//endothelial cell proliferation;GO:0048869//cellular developmental process gi|34328275|ref|NP_079906.2|/0/angiogenic factor with G patch and FHA domains 1 [Mus musculus] 76792 2670 7.11 6.146666667 -0.21004531 Down 0.321862424 2410131K14Rik RIKEN cDNA 2410131K14 gene - - - - gi|124486989|ref|NP_001074705.1|/2.69029e-105/UPF0454 protein C12orf49 homolog precursor [Mus musculus] 57080 3953.7 7.21 6.253333333 -0.205373837 Down 0.321862424 Gtf2ird1 general transcription factor II I repeat domain-containing 1 K03121|1|0.0|1778|cge:100769489|transcription initiation factor TFII-I GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organism development" "gi|148687492|gb|EDL19439.1|/0/mCG122432, isoform CRA_k, partial [Mus musculus]" 11546 1834 7.14 6.176666667 -0.209095599 Down 0.321862424 Parp2 "poly (ADP-ribose) polymerase family, member 2" K10798|1|0.0|1139|mmu:11546|poly [ADP-ribose] polymerase [EC:2.4.2.30] GO:0031981//nuclear lumen "GO:0003676//nucleic acid binding;GO:0016763//transferase activity, transferring pentosyl groups" GO:0006281//DNA repair;GO:0006486//protein glycosylation gi|6752992|ref|NP_033762.1|/0/poly [ADP-ribose] polymerase 2 [Mus musculus] 56700 1557 32.78333333 36.04666667 0.136903304 Up 0.321758998 Glmp glycosylated lysosomal membrane protein - GO:0031224//intrinsic component of membrane;GO:0005764//lysosome "GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000975//regulatory region DNA binding" GO:0007165//signal transduction;GO:0006366//transcription from RNA polymerase II promoter gi|9910458|ref|NP_064387.1|/0/lysosomal protein NCU-G1 precursor [Mus musculus] 73139 1044 11.93 13.39 0.166561918 Up 0.321636767 Cenpv centromere protein V K04650|1|8e-79|296|mgp:100539990|nuclear receptor co-repressor 1 "GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0005819//spindle" - GO:0016477//cell migration;GO:0000910//cytokinesis;GO:0007049//cell cycle;GO:0031055//chromatin remodeling at centromere gi|225703070|ref|NP_082724.1|/7.59999e-106/centromere protein V [Mus musculus] 75847 2827.49 1.99 1.503333333 -0.404603498 Down 0.321533341 Ispd isoprenoid synthase domain containing K09276|1|7e-61|238|umr:103659032|Y-box-binding protein 1 - "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006493//protein O-linked glycosylation;GO:0006720//isoprenoid metabolic process;GO:0006493//protein O-linked glycosylation;GO:0006720//isoprenoid metabolic process;GO:0006493//protein O-linked glycosylation;GO:0006720//isoprenoid metabolic process;GO:0006493//protein O-linked glycosylation;GO:0006720//isoprenoid metabolic process gi|157412261|ref|NP_848744.2|/0/isoprenoid synthase domain-containing protein isoform 1 [Mus musculus] 234700 640 0.173333333 0.446666667 1.365649472 Up 0.321448719 Nrn1l neuritin 1-like K05726|1|5e-11|69.7|lcm:102355909|breast cancer anti-estrogen resistance 1 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0048731//system development;GO:0048731//system development "gi|148679379|gb|EDL11326.1|/2.62991e-54/RIKEN cDNA G630049C14, isoform CRA_a, partial [Mus musculus]" 16848 2299 3.963333333 4.703333333 0.246969273 Up 0.321364098 Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase K05948|1|0.0|677|mmu:16848|fringe [EC:2.4.1.222] GO:0031228//intrinsic component of Golgi membrane GO:0043169//cation binding;GO:0008375//acetylglucosaminyltransferase activity GO:0007126//meiotic nuclear division;GO:0043393//regulation of protein binding;GO:0009952//anterior/posterior pattern specification;GO:0008585//female gonad development;GO:0007219//Notch signaling pathway;GO:0009653//anatomical structure morphogenesis "gi|6678680|ref|NP_032520.1|/0/beta-1,3-N-acetylglucosaminyltransferase lunatic fringe precursor [Mus musculus]" 74178 3523 34.36333333 31.15333333 -0.141483452 Down 0.321364098 Stk40 serine/threonine kinase 40 K16312|1|0.0|804|mmu:74178|serine/threonine-protein kinase 40 [EC:2.7.11.1] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|224922843|ref|NP_001139299.1|/0/serine/threonine-protein kinase 40 isoform a [Mus musculus] 74006 3992.59 22.72 20.50666667 -0.147869832 Down 0.321354696 Dnm1l dynamin 1-like K17065|1|0.0|1320|mcc:695388|dynamin 1-like protein [EC:3.6.5.5] GO:0032991//macromolecular complex;GO:0042579//microbody;GO:0015630//microtubule cytoskeleton;GO:0031966//mitochondrial membrane;GO:0032991//macromolecular complex;GO:0042579//microbody;GO:0015630//microtubule cytoskeleton;GO:0031966//mitochondrial membrane;GO:0032991//macromolecular complex;GO:0042579//microbody;GO:0015630//microtubule cytoskeleton;GO:0031966//mitochondrial membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0044389//ubiquitin-like protein ligase binding GO:0000266//mitochondrial fission;GO:0009306//protein secretion;GO:0022411;GO:0010822//positive regulation of mitochondrion organization;GO:0097193//intrinsic apoptotic signaling pathway;GO:0007031//peroxisome organization;GO:0003373;GO:0051260//protein homooligomerization;GO:0000266//mitochondrial fission;GO:0009306//protein secretion;GO:0022411;GO:0010822//positive regulation of mitochondrion organization;GO:0097193//intrinsic apoptotic signaling pathway;GO:0007031//peroxisome organization;GO:0009154//purine ribonucleotide catabolic process;GO:0003373;GO:0051260//protein homooligomerization;GO:0000266//mitochondrial fission;GO:0009306//protein secretion;GO:0010822//positive regulation of mitochondrion organization;GO:0097193//intrinsic apoptotic signaling pathway;GO:0007031//peroxisome organization;GO:0003373;GO:0051260//protein homooligomerization "gi|148665000|gb|EDK97416.1|/0/dynamin 1-like, isoform CRA_c, partial [Mus musculus]" 227634 7996 5.033333333 4.25 -0.244051302 Down 0.321326488 Camsap1 calmodulin regulated spectrin-associated protein 1 K17493|1|0.0|2900|mmu:227634|calmodulin-regulated spectrin-associated protein - - - gi|444741722|ref|NP_001263290.1|/0/calmodulin-regulated spectrin-associated protein 1 isoform 3 [Mus musculus] 18797 4273 8.94 7.813333333 -0.194336667 Down 0.321298281 Plcb3 "phospholipase C, beta 3" "K05858|1|0.0|2192|mmu:18797|phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]" GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005886//plasma membrane;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005886//plasma membrane GO:0004629//phospholipase C activity;GO:0046872//metal ion binding;GO:0060089;GO:0005515//protein binding;GO:0004629//phospholipase C activity;GO:0046872//metal ion binding;GO:0060089;GO:0005515//protein binding GO:0006644//phospholipid metabolic process;GO:0008217//regulation of blood pressure;GO:0007166//cell surface receptor signaling pathway;GO:0048193//Golgi vesicle transport;GO:0006644//phospholipid metabolic process;GO:0008217//regulation of blood pressure;GO:0007166//cell surface receptor signaling pathway;GO:0048193//Golgi vesicle transport "gi|31982122|ref|NP_032900.2|/0/1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform b [Mus musculus]" 72935 2213 8.006666667 9.14 0.19099242 Up 0.321298281 Ddx41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 K13116|1|0.0|1108|cge:100770508|ATP-dependent RNA helicase DDX41 [EC:3.6.4.13] GO:0031981//nuclear lumen;GO:0005681//spliceosomal complex "GO:0046914//transition metal ion binding;GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled" GO:0006366//transcription from RNA polymerase II promoter;GO:0002252;GO:0035456//response to interferon-beta gi|148709265|gb|EDL41211.1|/0/DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 [Mus musculus] 16859 1502.95 31.76333333 34.96 0.138342864 Up 0.321241867 Lgals9 "lectin, galactose binding, soluble 9" K10093|1|0.0|739|mmu:16859|galectin-9 GO:0044424;GO:0044424 GO:0005488//binding;GO:0005488//binding GO:0044765//single-organism transport;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0044765//single-organism transport;GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|226531139|ref|NP_001152773.1|/0/galectin-9 isoform 2 [Mus musculus] 214987 2942 15.35 17.1 0.15575767 Up 0.321223062 Chtf8 "CTF8, chromosome transmission fidelity factor 8" K11270|1|0.0|720|ggo:101149835|chromosome transmission fidelity protein 8 GO:0043231//intracellular membrane-bounded organelle - GO:0006259//DNA metabolic process;GO:0044763 gi|18606229|gb|AAH23107.1|/0/5830457O10Rik protein [Mus musculus] 319991 3528 0.563333333 0.926666667 0.718061636 Up 0.321204257 Kif6 kinesin family member 6 K10397|1|0.0|1530|mmu:319991|kinesin family member 6/9 GO:0015630//microtubule cytoskeleton GO:0003774//motor activity;GO:0032550 GO:0006928//movement of cell or subcellular component gi|156564374|ref|NP_796026.2|/0/kinesin-like protein KIF6 [Mus musculus] 234740 2887 1.08 1.513333333 0.486698484 Up 0.321185453 Tmem231 transmembrane protein 231 K19362|1|2e-172|609|mmu:234740|transmembrane protein 231 GO:0031224//intrinsic component of membrane;GO:0035869//ciliary transition zone;GO:0031090//organelle membrane GO:0005488//binding GO:0001654//eye development;GO:0010927;GO:0007507//heart development;GO:0007166//cell surface receptor signaling pathway;GO:0030154//cell differentiation;GO:0008104//protein localization;GO:0030326//embryonic limb morphogenesis gi|75677480|ref|NP_001028493.1|/1.38625e-171/transmembrane protein 231 [Mus musculus] 20928 7427.41 30.52 33.71333333 0.143564316 Up 0.321157245 Abcc9 "ATP-binding cassette, sub-family C (CFTR/MRP), member 9" K05033|1|0.0|2779|mmu:20928|ATP-binding cassette subfamily C (CFTR/MRP) member 9 GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0042383//sarcolemma;GO:0005887//integral component of plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0042383//sarcolemma;GO:0005887//integral component of plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0042383//sarcolemma;GO:0005887//integral component of plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0042383//sarcolemma;GO:0005887//integral component of plasma membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0004888//transmembrane signaling receptor activity;GO:0000149//SNARE binding;GO:0016247//channel regulator activity;GO:0015405;GO:0005261//cation channel activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0004888//transmembrane signaling receptor activity;GO:0000149//SNARE binding;GO:0016247//channel regulator activity;GO:0015405;GO:0005261//cation channel activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0004888//transmembrane signaling receptor activity;GO:0000149//SNARE binding;GO:0016247//channel regulator activity;GO:0015405;GO:0005261//cation channel activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0004888//transmembrane signaling receptor activity;GO:0000149//SNARE binding;GO:0016247//channel regulator activity;GO:0015405;GO:0005261//cation channel activity GO:0001667//ameboidal-type cell migration;GO:0042221//response to chemical;GO:0071805//potassium ion transmembrane transport;GO:0002252;GO:0001667//ameboidal-type cell migration;GO:0042221//response to chemical;GO:0071805//potassium ion transmembrane transport;GO:0002252;GO:0001667//ameboidal-type cell migration;GO:0042221//response to chemical;GO:0071805//potassium ion transmembrane transport;GO:0002252;GO:0001667//ameboidal-type cell migration;GO:0042221//response to chemical;GO:0071805//potassium ion transmembrane transport;GO:0002252 gi|113722105|ref|NP_066379.2|/0/ATP-binding cassette sub-family C member 9 isoform c [Mus musculus] 67375 1211 0.046666667 0.266666667 2.514573173 Up 0.321100831 Qprt quinolinate phosphoribosyltransferase K00767|1|2e-152|540|mmu:67375|nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] GO:0044424 "GO:0016763//transferase activity, transferring pentosyl groups;GO:0042802//identical protein binding" GO:0043649//dicarboxylic acid catabolic process;GO:0006461//protein complex assembly;GO:0019359//nicotinamide nucleotide biosynthetic process gi|19526852|ref|NP_598447.1|/1.9788e-151/nicotinate-nucleotide pyrophosphorylase [carboxylating] [Mus musculus] 27226 1923 6.163333333 7.11 0.206138741 Up 0.321072624 Pla2g7 "phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)" K01062|1|0.0|896|mmu:27226|platelet-activating factor acetylhydrolase [EC:3.1.1.47] GO:0034358//plasma lipoprotein particle GO:0008289//lipid binding;GO:0004623//phospholipase A2 activity GO:0006629//lipid metabolic process;GO:0006954//inflammatory response;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0034369//plasma lipoprotein particle remodeling;GO:0042161 gi|31980752|ref|NP_038765.2|/0/platelet-activating factor acetylhydrolase precursor [Mus musculus] 55982 5864 6.093333333 7.046666667 0.209709306 Up 0.321072624 Paxip1 PAX interacting (with transcription-activation domain) protein 1 K14972|1|0.0|937|mmu:55982|PAX-interacting protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0034708 GO:0005488//binding GO:0002699//positive regulation of immune effector process;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0042770//signal transduction in response to DNA damage;GO:0031062//positive regulation of histone methylation;GO:0006259//DNA metabolic process;GO:0048513//animal organ development;GO:0016567//protein ubiquitination;GO:0044767//single-organism developmental process;GO:0009314//response to radiation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0034968//histone lysine methylation;GO:0016477//cell migration;GO:0016573//histone acetylation gi|42734451|ref|NP_061366.2|/0/PAX-interacting protein 1 [Mus musculus] 213989 2066 20.38333333 22.57333333 0.147229474 Up 0.321053819 Tmem82 transmembrane protein 82 "K03847|1|3e-08|43.5|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" GO:0031224//intrinsic component of membrane - - gi|77020279|ref|NP_666099.2|/4.64816e-147/transmembrane protein 82 [Mus musculus] 68021 1224 15.16 16.90333333 0.15703802 Up 0.32101621 Bphl "biphenyl hydrolase-like (serine hydrolase, breast epithelial mucin-associated antigen)" K18399|1|3e-148|527|mmu:68021|valacyclovir hydrolase [EC:3.1.-.-] GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity - gi|26347073|dbj|BAC37185.1|/2.00936e-151/unnamed protein product [Mus musculus] 330941 5635 0.37 0.12 -1.624490865 Down 0.320884576 AI593442 expressed sequence AI593442 - - - - gi|26343487|dbj|BAC35400.1|/2.24082e-62/unnamed protein product [Mus musculus] 12340 3187 12.81333333 11.37333333 -0.171990689 Down 0.320856369 Capza1 "capping protein (actin filament) muscle Z-line, alpha 1" "K10364|1|4e-156|555|mmu:12340|capping protein (actin filament) muscle Z-line, alpha" GO:0043234//protein complex;GO:0015629//actin cytoskeleton GO:0003779//actin binding GO:0051693//actin filament capping gi|161086971|ref|NP_033927.2|/3.47222e-155/F-actin-capping protein subunit alpha-1 [Mus musculus] 68889 2168 19.98666667 22.16333333 0.149136994 Up 0.32078115 Ubac2 ubiquitin associated domain containing 2 K14589|1|9e-66|254|myb:102261455|cap1 methyltransferase [EC:2.1.1.57] GO:0031224//intrinsic component of membrane - - gi|90568036|ref|NP_081137.2|/3.50094e-169/ubiquitin-associated domain-containing protein 2 precursor [Mus musculus] 13846 4338.62 34.75 31.62666667 -0.135871469 Down 0.320517883 Ephb4 Eph receptor B4 K05113|1|0.0|1891|mmu:13846|Eph receptor B4 [EC:2.7.10.1] GO:0016021//integral component of membrane;GO:0044464;GO:0016021//integral component of membrane;GO:0044464 GO:0032550;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032550;GO:0004714//transmembrane receptor protein tyrosine kinase activity GO:0006468//protein phosphorylation;GO:0022610;GO:0009887//organ morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0002040//sprouting angiogenesis;GO:0006468//protein phosphorylation;GO:0022610;GO:0009887//organ morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0002040//sprouting angiogenesis gi|227330573|ref|NP_034274.4|/0/ephrin type-B receptor 4 isoform b precursor [Mus musculus] 15193 2295.64 30.34666667 33.47 0.141330494 Up 0.320517883 Hdgfrp2 "hepatoma-derived growth factor, related protein 2" K16641|1|3e-37|159|lcm:102349153|hepatoma-derived growth factor - - - - 214290 5569 5.663333333 4.84 -0.226644399 Down 0.320499079 Zcchc6 "zinc finger, CCHC domain containing 6" K13291|1|0.0|2665|mmu:214290|terminal uridylyltransferase [EC:2.7.7.52] - - - "gi|148709347|gb|EDL41293.1|/0/zinc finger, CCHC domain containing 6, isoform CRA_b, partial [Mus musculus]" 56738 2652.75 9.25 10.5 0.182864057 Up 0.320433262 Mocs1 molybdenum cofactor synthesis 1 K03639|1|0.0|1237|mmu:56738|cyclic pyranopterin phosphate synthase [EC:4.1.99.18] GO:0043234//protein complex;GO:0043234//protein complex GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding GO:0009108//coenzyme biosynthetic process;GO:0018130;GO:0009108//coenzyme biosynthetic process;GO:0018130 gi|161484628|ref|NP_064426.2|/0/molybdenum cofactor biosynthesis protein 1 isoform 1 [Mus musculus] 75871 2161.13 4.17 4.936666667 0.243489851 Up 0.320292226 Zfp821 zinc finger protein 821 K02981|1|4e-14|82.8|cjc:100393981|small subunit ribosomal protein S2e;K20210|2|8e-09|65.1|lve:103087041|ras-responsive element-binding protein 1 GO:0005622//intracellular;GO:0005622//intracellular;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148679486|gb|EDL11433.1|/4.23237e-175/RIKEN cDNA 4930566A11, isoform CRA_b, partial [Mus musculus]" 108707 2444 6.916666667 7.94 0.199062077 Up 0.320264019 Fam207a "family with sequence similarity 207, member A" - - - - gi|19527218|ref|NP_598759.1|/1.20506e-88/protein FAM207A [Mus musculus] 102466254 136 4.523333333 3.796666667 -0.252652974 Down 0.320207605 Mir3473f microRNA 3473f - - - - - 71777 3755 2.736666667 2.173333333 -0.332510258 Down 0.32015119 Ing3 "inhibitor of growth family, member 3" K11319|1|0.0|674|mmu:71777|inhibitor of growth protein 3 - - - - 12368 1475 5.89 6.83 0.213617944 Up 0.32015119 Casp6 caspase 6 K04396|1|3e-162|573|mmu:12368|caspase 6 [EC:3.4.22.59] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0004175//endopeptidase activity GO:0012502//induction of programmed cell death;GO:0010038//response to metal ion;GO:0010212//response to ionizing radiation;GO:0000302//response to reactive oxygen species;GO:0002526//acute inflammatory response;GO:0009746;GO:0043627//response to estrogen;GO:0043065//positive regulation of apoptotic process;GO:0019538//protein metabolic process gi|157951736|ref|NP_033941.3|/2.7945e-161/caspase-6 precursor [Mus musculus] 12959 819 6.946666667 6.01 -0.208955881 Down 0.32015119 Cryba4 "crystallin, beta A4" K16810|1|9e-18|92.8|bacu:103015945|TBCC domain-containing protein 1;K01886|3|3e-12|74.3|ccw:104683491|glutaminyl-tRNA synthetase [EC:6.1.1.18] - - - - 232337 1114 14.86333333 16.57 0.156815904 Up 0.320113581 Zfp637 zinc finger protein 637 K09228|1|3e-74|281|shr:100930227|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - gi|564348576|ref|XP_006237256.1|/1.41894e-177/PREDICTED: zinc finger protein 32 isoform X3 [Rattus norvegicus] 69642 1224 67.1 73.46666667 0.130777052 Up 0.320094776 Mlip muscular LMNA-interacting protein - GO:0012505//endomembrane system;GO:0016604//nuclear body - - gi|241666474|ref|NP_081426.1|/1.14364e-138/muscular LMNA-interacting protein [Mus musculus] 11836 2021.21 30.17666667 33.24333333 0.139631596 Up 0.31999135 Araf "Araf proto-oncogene, serine/threonine kinase" K08845|1|0.0|1164|mmu:11836|A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] - - - - 70428 4858 2.886666667 2.316666667 -0.317354047 Down 0.31999135 Polr3b polymerase (RNA) III (DNA directed) polypeptide B K03021|1|0.0|2286|mmu:70428|DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6] GO:0031981//nuclear lumen GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity;GO:0001882//nucleoside binding GO:0006383//transcription from RNA polymerase III promoter;GO:0031349//positive regulation of defense response;GO:0032481//positive regulation of type I interferon production;GO:0002252 gi|46195739|ref|NP_081699.1|/0/DNA-directed RNA polymerase III subunit RPC2 [Mus musculus] 70615 3658 2.833333333 2.263333333 -0.324051267 Down 0.31999135 Ankrd24 ankyrin repeat domain 24 K15503|1|9e-24|115|cmy:102935647|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B - - - "gi|148699437|gb|EDL31384.1|/0/ankyrin repeat domain 24, isoform CRA_b, partial [Mus musculus]" 73667 1758 0.223333333 0.506666667 1.181838323 Up 0.319887924 2410004P03Rik RIKEN cDNA 2410004P03 gene K13696|1|2e-06|47.8|bfo:BRAFLDRAFT_117028|abhydrolase domain-containing protein 1/3 - - - gi|318804024|ref|NP_001188262.1|/1.26964e-118/uncharacterized protein C2orf50 homolog isoform 2 [Mus musculus] 56748 965.37 69.04666667 75.32 0.125461232 Up 0.319822107 Nfu1 NFU1 iron-sulfur cluster scaffold - - - - "gi|282154803|ref|NP_001164062.1|/3.92368e-122/NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform 1 precursor [Mus musculus] " 71956 1959 2.483333333 3.07 0.305960731 Up 0.319775095 Rnf135 ring finger protein 135 K16272|1|0.0|824|mmu:71956|E3 ubiquitin-protein ligase RNF135 [EC:2.3.2.27] GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0032446//protein modification by small protein conjugation;GO:0001818//negative regulation of cytokine production;GO:0032481//positive regulation of type I interferon production;GO:0031347//regulation of defense response gi|21312628|ref|NP_082295.1|/0/E3 ubiquitin-protein ligase RNF135 [Mus musculus] 13617 3643 21.76 19.63 -0.148618384 Down 0.319765693 Ednra endothelin receptor type A K04197|1|0.0|832|mmu:13617|endothelin receptor type A GO:0031224//intrinsic component of membrane;GO:0042383//sarcolemma;GO:0005635//nuclear envelope GO:0004672//protein kinase activity;GO:0008528//G-protein coupled peptide receptor activity;GO:0005488//binding GO:0097205//renal filtration;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0006954//inflammatory response;GO:0001932//regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0009612//response to mechanical stimulus;GO:0043009//chordate embryonic development;GO:0008645//hexose transport;GO:0014820//tonic smooth muscle contraction;GO:0051094//positive regulation of developmental process;GO:0046903//secretion;GO:0043410//positive regulation of MAPK cascade;GO:0042476//odontogenesis;GO:0014072//response to isoquinoline alkaloid;GO:0007620//copulation;GO:0007600//sensory perception;GO:0033002//muscle cell proliferation;GO:0042127//regulation of cell proliferation;GO:0007265//Ras protein signal transduction;GO:0007567//parturition;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0050880//regulation of blood vessel size;GO:0002237//response to molecule of bacterial origin;GO:0048483//autonomic nervous system development;GO:0001525//angiogenesis;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0006171//cAMP biosynthetic process;GO:0014031//mesenchymal cell development gi|45383740|ref|NP_034462.1|/0/endothelin-1 receptor precursor [Mus musculus] 100504464 2134 0.703333333 1.083333333 0.623196719 Up 0.319728083 E230016K23Rik RIKEN cDNA E230016K23 gene - - - - - 320685 2721 0.51 0.226666667 -1.169925001 Down 0.319643462 Dctd dCMP deaminase K01493|1|1e-69|267|mmu:320685|dCMP deaminase [EC:3.5.4.12] - "GO:0046914//transition metal ion binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0046914//transition metal ion binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0046914//transition metal ion binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0046914//transition metal ion binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines" GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process gi|568954869|ref|XP_006509506.1|/5.94995e-84/PREDICTED: deoxycytidylate deaminase isoform X3 [Mus musculus] 68002 675 20.97666667 18.85666667 -0.153710772 Down 0.319605852 Sdhaf4 succinate dehydrogenase complex assembly factor 4 - - - - - 54130 2742 64.97 71.05 0.129060944 Up 0.319455414 Actr1a "ARP1 actin-related protein 1A, centractin alpha" K16575|1|0.0|755|pale:102892874|centractin GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0044444//cytoplasmic part GO:0032550 GO:0002478;GO:0006810//transport;GO:0044772//mitotic cell cycle phase transition gi|431895484|gb|ELK05000.1|/0/Alpha-centractin [Pteropus alecto] 195040 1353 5.48 4.67 -0.230753343 Down 0.319342585 Tmem199 transmembrane protein 199 K20187|1|3e-23|112|tad:TRIADDRAFT_60361|biogenesis of lysosome-related organelles complex 1 subunit 5;K10399|2|1e-20|103|fpg:101917652|kinesin family member 12 GO:0031224//intrinsic component of membrane - - gi|72384367|ref|NP_954669.2|/1.29008e-109/transmembrane protein 199 [Mus musculus] 69038 428 62.9 68.87666667 0.130955307 Up 0.319257964 Tmem258 transmembrane protein 258 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|676593996|gb|KFO80499.1|/9.94484e-27/Transmembrane protein 258, partial [Cuculus canorus]" 50754 3830.54 5.983333333 6.91 0.207736272 Up 0.319239159 Fbxw7 F-box and WD-40 domain protein 7 K10260|1|0.0|1215|mmu:50754|F-box and WD-40 domain protein 7 - - - - 70484 2276 1.256666667 0.86 -0.547193458 Down 0.31916394 Slc35d2 "solute carrier family 35, member D2" K15281|1|2e-165|585|mmu:70484|solute carrier family 35 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0044765//single-organism transport gi|110625735|ref|NP_001001321.2|/1.61792e-164/UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter [Mus musculus] 85030 1633.1 0.853333333 1.25 0.550746785 Up 0.31916394 Tnfrsf25 "tumor necrosis factor receptor superfamily, member 25" K05160|1|0.0|639|mmu:85030|tumor necrosis factor receptor superfamily member 25 - - - - 21832 2416 0.326666667 0.083333333 -1.970853654 Down 0.319060514 Thpo thrombopoietin K06854|1|9e-163|576|mmu:21832|thrombopoietin GO:0044421;GO:0044421 GO:0005102//receptor binding;GO:0005102//receptor binding GO:0030097//hemopoiesis;GO:0008283//cell proliferation;GO:0030097//hemopoiesis;GO:0002237//response to molecule of bacterial origin;GO:0008283//cell proliferation gi|568995030|ref|XP_006522050.1|/0/PREDICTED: thrombopoietin isoform X1 [Mus musculus] 52639 1817 66.68 60.80666667 -0.133024599 Down 0.319051111 Wipi1 "WD repeat domain, phosphoinositide interacting 1" K17908|1|0.0|852|mmu:52639|autophagy-related protein 18 - - - gi|22122367|ref|NP_666052.1|/0/WD repeat domain phosphoinositide-interacting protein 1 [Mus musculus] 219131 1371 1.496666667 1.973333333 0.398881731 Up 0.319051111 Phf11a PHD finger protein 11A K18494|1|8e-105|383|mmu:107303348|histone-lysine N-methyltransferase SETDB2 [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|27369858|ref|NP_766191.1|/1.43226e-172/PHD finger protein 11A [Mus musculus] 56504 2000 14.18 15.85 0.160625308 Up 0.319032307 Srpk3 serine/arginine-rich protein specific kinase 3 K08832|1|0.0|943|mmu:56504|serine/threonine-protein kinase SRPK3 [EC:2.7.11.1] - - - - 18570 1524 20.78 18.69 -0.152929085 Down 0.318985295 Pdcd6 programmed cell death 6 "K08585|1|3e-18|95.9|cfo:105251302|calpain, invertebrate [EC:3.4.22.-];K08584|4|2e-17|93.2|cfa:487273|calpain, small subunit 2" GO:0031982//vesicle;GO:0031090//organelle membrane;GO:0005635//nuclear envelope GO:0046872//metal ion binding;GO:0042802//identical protein binding GO:0010038//response to metal ion;GO:0006915//apoptotic process;GO:0007165//signal transduction;GO:0006950//response to stress;GO:0015031//protein transport gi|537222089|gb|ERE82592.1|/5.7713e-109/programmed cell death protein 6 [Cricetulus griseus] 269799 1592 4.146666667 4.906666667 0.242791186 Up 0.31892888 Clec4a1 "C-type lectin domain family 4, member a1" K10057|1|4e-122|441|mmu:269799|C-type lectin domain family 4 member A - - - "gi|47059161|ref|NP_955015.1|/3.12998e-121/C-type lectin domain family 4, member a1 [Mus musculus]" 18741 1808 0.083333333 0.32 1.941106311 Up 0.318910076 Pitx2 paired-like homeodomain transcription factor 2 K04686|1|1e-143|513|rno:54284|paired-like homeodomain transcription factor 2 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle "GO:0001085//RNA polymerase II transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0042802//identical protein binding;GO:0003682//chromatin binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0042802//identical protein binding;GO:0003682//chromatin binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0042802//identical protein binding;GO:0003682//chromatin binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0042802//identical protein binding;GO:0003682//chromatin binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding" GO:0030326//embryonic limb morphogenesis;GO:0048534//hematopoietic or lymphoid organ development;GO:0008284//positive regulation of cell proliferation;GO:0008406//gonad development;GO:0043009//chordate embryonic development;GO:0048546//digestive tract morphogenesis;GO:0021984//adenohypophysis development;GO:0042476//odontogenesis;GO:0003170//heart valve development;GO:0009798//axis specification;GO:0003151//outflow tract morphogenesis;GO:0003281//ventricular septum development;GO:0003209//cardiac atrium morphogenesis;GO:0000768//syncytium formation by plasma membrane fusion;GO:0043010//camera-type eye development;GO:0007166//cell surface receptor signaling pathway;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0060425//lung morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0048845//venous blood vessel morphogenesis;GO:0001525//angiogenesis;GO:0033273//response to vitamin;GO:0051099//positive regulation of binding;GO:0021539//subthalamus development;GO:0009855//determination of bilateral symmetry;GO:0009913//epidermal cell differentiation;GO:0001755//neural crest cell migration;GO:0007519//skeletal muscle tissue development;GO:0009719;GO:0030326//embryonic limb morphogenesis;GO:0048534//hematopoietic or lymphoid organ development;GO:0008284//positive regulation of cell proliferation;GO:0008406//gonad development;GO:0043009//chordate embryonic development;GO:0048546//digestive tract morphogenesis;GO:0021984//adenohypophysis development;GO:0042476//odontogenesis;GO:0003170//heart valve development;GO:0009798//axis specification;GO:0003151//outflow tract morphogenesis;GO:0003281//ventricular septum development;GO:0003209//cardiac atrium morphogenesis;GO:0000768//syncytium formation by plasma membrane fusion;GO:0043010//camera-type eye development;GO:0007166//cell surface receptor signaling pathway;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0060425//lung morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0048845//venous blood vessel morphogenesis;GO:0001525//angiogenesis;GO:0033273//response to vitamin;GO:0051099//positive regulation of binding;GO:0021539//subthalamus development;GO:0009855//determination of bilateral symmetry;GO:0009913//epidermal cell differentiation;GO:0001755//neural crest cell migration;GO:0007519//skeletal muscle tissue development;GO:0009719;GO:0030326//embryonic limb morphogenesis;GO:0048534//hematopoietic or lymphoid organ development;GO:0008284//positive regulation of cell proliferation;GO:0008406//gonad development;GO:0043009//chordate embryonic development;GO:0048546//digestive tract morphogenesis;GO:0021984//adenohypophysis development;GO:0042476//odontogenesis;GO:0003170//heart valve development;GO:0009798//axis specification;GO:0003151//outflow tract morphogenesis;GO:0003281//ventricular septum development;GO:0003209//cardiac atrium morphogenesis;GO:0000768//syncytium formation by plasma membrane fusion;GO:0043010//camera-type eye development;GO:0007166//cell surface receptor signaling pathway;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0060425//lung morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0048845//venous blood vessel morphogenesis;GO:0001525//angiogenesis;GO:0033273//response to vitamin;GO:0051099//positive regulation of binding;GO:0021539//subthalamus development;GO:0009855//determination of bilateral symmetry;GO:0009913//epidermal cell differentiation;GO:0001755//neural crest cell migration;GO:0007519//skeletal muscle tissue development;GO:0009719;GO:0030326//embryonic limb morphogenesis;GO:0048534//hematopoietic or lymphoid organ development;GO:0008284//positive regulation of cell proliferation;GO:0008406//gonad development;GO:0043009//chordate embryonic development;GO:0048546//digestive tract morphogenesis;GO:0021984//adenohypophysis development;GO:0042476//odontogenesis;GO:0003170//heart valve development;GO:0009798//axis specification;GO:0003151//outflow tract morphogenesis;GO:0003281//ventricular septum development;GO:0003209//cardiac atrium morphogenesis;GO:0000768//syncytium formation by plasma membrane fusion;GO:0043010//camera-type eye development;GO:0007166//cell surface receptor signaling pathway;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0060425//lung morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0048845//venous blood vessel morphogenesis;GO:0001525//angiogenesis;GO:0033273//response to vitamin;GO:0051099//positive regulation of binding;GO:0021539//subthalamus development;GO:0009855//determination of bilateral symmetry;GO:0009913//epidermal cell differentiation;GO:0001755//neural crest cell migration;GO:0007519//skeletal muscle tissue development;GO:0009719 gi|109948275|ref|NP_001035967.1|/5.53563e-144/pituitary homeobox 2 isoform c [Mus musculus] 386454 1446 0.726666667 1.106666667 0.606855107 Up 0.318863064 Rnf39 ring finger protein 39 K12000|1|3e-30|135|oaa:100085071|tripartite motif-containing protein 7;K12015|2|4e-30|135|apla:101805457|tripartite motif-containing protein 39 [EC:2.3.2.27] GO:0044424 GO:0046914//transition metal ion binding GO:0048167//regulation of synaptic plasticity gi|153791477|ref|NP_001093102.1|/0/RING finger protein 39 [Mus musculus] 26408 5393 10.16 8.943333333 -0.184015848 Down 0.318787845 Map3k5 mitogen-activated protein kinase kinase kinase 5 K04426|1|0.0|2464|mmu:26408|mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25] GO:0043231//intracellular membrane-bounded organelle GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0046872//metal ion binding;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0042802//identical protein binding;GO:0019902//phosphatase binding;GO:0019900//kinase binding GO:0070301//cellular response to hydrogen peroxide;GO:0006915//apoptotic process;GO:0006468//protein phosphorylation;GO:0006952//defense response;GO:0051403//stress-activated MAPK cascade gi|171846249|ref|NP_032606.4|/0/mitogen-activated protein kinase kinase kinase 5 [Mus musculus] 20210 531 0.01 0.17 4.087462841 Up 0.318703223 Saa3 serum amyloid A 3 K17310|1|1e-59|230|mmu:20210|serum amyloid A protein GO:0034358//plasma lipoprotein particle - GO:0002526//acute inflammatory response gi|6755396|ref|NP_035445.1|/1.00328e-58/serum amyloid A-3 protein precursor [Mus musculus] 100502967 1190 0.01 0.173333333 4.115477217 Up 0.318703223 Speer4c spermatogenesis associated glutamate (E)-rich protein 4C - - - - gi|528078320|ref|NP_001268440.1|/4.32915e-119/spermatogenesis associated glutamate (E)-rich protein 4c [Mus musculus] 73272 872 0.173333333 0.01 -4.115477217 Down 0.318703223 1700108F19Rik RIKEN cDNA 1700108F19 gene - - - - - 244334 287 0.01 0.17 4.087462841 Up 0.318703223 Defb8 defensin beta 8 - - - GO:0006952//defense response gi|147899924|ref|NP_694748.3|/5.08323e-18/beta-defensin 8 precursor [Mus musculus] 72277 621 0.01 0.17 4.087462841 Up 0.318703223 1700030F18Rik RIKEN cDNA 1700030F18 gene - - - - gi|223590206|sp|Q9D9R9.2|F186A_MOUSE/6.10371e-58/RecName: Full=Protein FAM186A 210321 572 0.17 0.01 -4.087462841 Down 0.318703223 BC048679 cDNA sequence BC048679 - - - - gi|300796845|ref|NP_001180203.1|/6.90277e-86/uncharacterized protein LOC210321 isoform 1 [Mus musculus] 73813 2900 0.173333333 0.01 -4.115477217 Down 0.318703223 Fam83e "family with sequence similarity 83, member E" K16805|1|9e-43|178|cjo:107322877|protein FAM83D - - - gi|167000146|ref|NP_001028342.2|/0/protein FAM83E [Mus musculus] 85029 325 0.01 0.173333333 4.115477217 Up 0.318703223 Rpph1 ribonuclease P RNA component H1 - - - - gi|426376198|ref|XP_004054894.1|/2.72434e-13/PREDICTED: uncharacterized protein LOC101140100 [Gorilla gorilla gorilla] 56458 5552 12.67666667 11.29 -0.167129952 Down 0.318693821 Foxo1 forkhead box O1 K07201|1|0.0|1040|mmu:56458|forkhead box protein O1 - - - gi|34328255|ref|NP_062713.2|/0/forkhead box protein O1 [Mus musculus] 108155 5252.39 12.20333333 10.81 -0.17490875 Down 0.318693821 Ogt O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) K09667|1|0.0|2124|mmu:108155|protein O-GlcNAc transferase [EC:2.4.1.255] GO:0005815//microtubule organizing center;GO:0035097//histone methyltransferase complex;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0035097//histone methyltransferase complex;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0030234//enzyme regulator activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0010485//H4 histone acetyltransferase activity;GO:0030246//carbohydrate binding;GO:0033218//amide binding;GO:0043168//anion binding;GO:0030234//enzyme regulator activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0010485//H4 histone acetyltransferase activity;GO:0030246//carbohydrate binding;GO:0033218//amide binding;GO:0043168//anion binding GO:0006486//protein glycosylation;GO:0044093;GO:0048017//inositol lipid-mediated signaling;GO:0018023//peptidyl-lysine trimethylation;GO:0006096//glycolytic process;GO:0031667//response to nutrient levels;GO:0051260//protein homooligomerization;GO:0006508//proteolysis;GO:0012502//induction of programmed cell death;GO:0016601//Rac protein signal transduction;GO:0043967//histone H4 acetylation;GO:0031062//positive regulation of histone methylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0032526//response to retinoic acid;GO:0008286//insulin receptor signaling pathway;GO:0006486//protein glycosylation;GO:0044093;GO:0048017//inositol lipid-mediated signaling;GO:0018023//peptidyl-lysine trimethylation;GO:0006096//glycolytic process;GO:0031667//response to nutrient levels;GO:0051260//protein homooligomerization;GO:0006508//proteolysis;GO:0012502//induction of programmed cell death;GO:0016601//Rac protein signal transduction;GO:0043967//histone H4 acetylation;GO:0031062//positive regulation of histone methylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0032526//response to retinoic acid;GO:0008286//insulin receptor signaling pathway gi|46909607|ref|NP_631883.2|/0/UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform 1 [Mus musculus] 52679 5476 0.806666667 0.47 -0.779311885 Down 0.318693821 E2f7 E2F transcription factor 7 K09391|1|0.0|1746|mmu:52679|transcription factor E2F7/8 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding GO:0001525//angiogenesis;GO:0042770//signal transduction in response to DNA damage;GO:0008283//cell proliferation;GO:0060706//cell differentiation involved in embryonic placenta development;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0032875//regulation of DNA endoreduplication;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0001889//liver development;GO:0000910//cytokinesis gi|40254337|ref|NP_848724.2|/0/transcription factor E2F7 [Mus musculus] 108138 1557 3.146666667 3.803333333 0.273440027 Up 0.318693821 Xrcc4 X-ray repair complementing defective repair in Chinese hamster cells 4 K10886|1|0.0|647|mmu:108138|DNA-repair protein XRCC4 GO:0005694//chromosome;GO:0044428//nuclear part;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0003824//catalytic activity GO:0030217//T cell differentiation;GO:0043085//positive regulation of catalytic activity;GO:0000726;GO:0043066//negative regulation of apoptotic process;GO:0010720//positive regulation of cell development;GO:0043009//chordate embryonic development;GO:0008284//positive regulation of cell proliferation;GO:0006266//DNA ligation;GO:0002320//lymphoid progenitor cell differentiation;GO:0010212//response to ionizing radiation;GO:0007399//nervous system development;GO:0002204//somatic recombination of immunoglobulin genes involved in immune response;GO:0010226//response to lithium ion gi|21312636|ref|NP_082288.1|/0/DNA repair protein XRCC4 [Mus musculus] 22282 2419 60.83666667 66.56 0.129714326 Up 0.318618602 Usf2 upstream transcription factor 2 K09106|1|7e-168|593|rno:81817|upstream stimulatory factor GO:0043231//intracellular membrane-bounded organelle "GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0043566//structure-specific DNA binding;GO:0008134//transcription factor binding" GO:0009299//mRNA transcription;GO:0007589//body fluid secretion;GO:0048878//chemical homeostasis;GO:0000430//regulation of transcription from RNA polymerase II promoter by glucose gi|74147177|dbj|BAE27494.1|/6.38285e-167/unnamed protein product [Mus musculus] 12819 5335 21.06333333 18.99 -0.14949386 Down 0.318590395 Col15a1 "collagen, type XV, alpha 1" "K08135|1|0.0|1908|mmu:12819|collagen, type XV, alpha" GO:0005578//proteinaceous extracellular matrix - - gi|134288882|ref|NP_034058.2|/0/collagen alpha-1(XV) chain precursor [Mus musculus] 102093 4640 8.96 7.873333333 -0.186524173 Down 0.31857159 Phkb phosphorylase kinase beta K07190|1|0.0|2140|mmu:102093|phosphorylase kinase alpha/beta subunit GO:0043234//protein complex;GO:0016020//membrane "GO:0004683//calmodulin-dependent protein kinase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0005515//protein binding" GO:0006464//cellular protein modification process;GO:0006073//cellular glucan metabolic process gi|40789096|ref|NP_955517.1|/0/phosphorylase b kinase regulatory subunit beta [Mus musculus] 17979 7571 8.8 7.713333333 -0.190149065 Down 0.31857159 Ncoa3 nuclear receptor coactivator 3 K11256|1|0.0|2313|mmu:17979|nuclear receptor coactivator 3 [EC:2.3.1.48] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0060089;GO:0003676//nucleic acid binding;GO:0003713//transcription coactivator activity;GO:0035258//steroid hormone receptor binding;GO:0008080//N-acetyltransferase activity GO:0010556;GO:0006366//transcription from RNA polymerase II promoter;GO:0016570//histone modification;GO:0006915//apoptotic process;GO:0009967//positive regulation of signal transduction;GO:0044093;GO:0030540//female genitalia development;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0016049//cell growth;GO:0030216//keratinocyte differentiation gi|118026946|ref|NP_032705.2|/0/nuclear receptor coactivator 3 [Mus musculus] 67510 1748 5.216666667 6.063333333 0.216982886 Up 0.318562187 Tvp23b trans-golgi network vesicle protein 23B - GO:0031224//intrinsic component of membrane - - gi|21312930|ref|NP_080486.1|/3.20663e-114/Golgi apparatus membrane protein TVP23 homolog B [Mus musculus] 52398 5407.48 5.946666667 5.093333333 -0.223471072 Down 0.318562187 11-Sep septin 11 K16939|1|0.0|704|rno:305227|septin 6/8/11 GO:0030425//dendrite;GO:0032156//septin cytoskeleton;GO:0032432//actin filament bundle;GO:0030425//dendrite;GO:0032156//septin cytoskeleton;GO:0032432//actin filament bundle;GO:0030425//dendrite;GO:0032156//septin cytoskeleton;GO:0032432//actin filament bundle GO:0032550;GO:0032550;GO:0032550 GO:0044763;GO:0051259//protein oligomerization;GO:0044763;GO:0051259//protein oligomerization;GO:0044763;GO:0051259//protein oligomerization gi|893562355|ref|NP_001297598.1|/0/septin-11 isoform 1 [Mus musculus] 234219 1548 0.62 0.313333333 -0.984569959 Down 0.318477566 Helt helt bHLH transcription factor K09091|1|7e-22|107|aqu:100640672|hairy and enhancer of split related with YRPW motif GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity GO:0040007//growth;GO:0006366//transcription from RNA polymerase II promoter;GO:0007631//feeding behavior;GO:0097154//GABAergic neuron differentiation "gi|148703622|gb|EDL35569.1|/2.88714e-156/Hey-like transcription factor (zebrafish), isoform CRA_a, partial [Mus musculus]" 246196 2454 14.26333333 15.91666667 0.158227054 Up 0.318402347 Zfp277 zinc finger protein 277 K07575|1|1e-20|103|tsp:Tsp_02810|PUA domain protein;K11436|2|2e-06|57.4|cmk:103175001|type I protein arginine methyltransferase [EC:2.1.1.319] GO:0044464;GO:0044464 GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - "gi|148704875|gb|EDL36822.1|/0/mCG61794, isoform CRA_c, partial [Mus musculus]" 240892 4038.84 18.24333333 20.30333333 0.154347248 Up 0.318392944 Dusp27 dual specificity phosphatase 27 (putative) K14165|1|0.0|1714|mmu:240892|atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] - GO:0042578//phosphoric ester hydrolase activity;GO:0042578//phosphoric ester hydrolase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process gi|229892201|ref|NP_001028516.2|/0/inactive dual specificity phosphatase 27 [Mus musculus] 67457 3166 4.73 5.53 0.225439297 Up 0.318289518 Frmd8 FERM domain containing 8 K17705|1|1e-20|105|bfo:BRAFLDRAFT_265772|Krev interaction trapped protein 1 GO:0043232 - - gi|13385676|ref|NP_080445.1|/0/FERM domain-containing protein 8 [Mus musculus] 93723 4764 0.946666667 0.59 -0.682141569 Down 0.318223702 Pcdhga11 "protocadherin gamma subfamily A, 11" K16495|1|0.0|1727|mmu:93723|protocadherin gamma subfamily A - - - - 319475 2691.9 18.63333333 20.68666667 0.150815414 Up 0.318110873 Zfp672 zinc finger protein 672 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148675800|gb|EDL07747.1|/0/zinc finger protein 672, isoform CRA_a, partial [Mus musculus]" 69938 1777 2.663333333 2.113333333 -0.333712663 Down 0.318054459 Scrn1 secernin 1 K14358|1|0.0|851|mmu:69938|secernin GO:0005635//nuclear envelope GO:0008238//exopeptidase activity GO:0019538//protein metabolic process;GO:0016192//vesicle-mediated transport gi|37359832|dbj|BAC97894.1|/0/mKIAA0193 protein [Mus musculus] 223870 6415 2.153333333 2.703333333 0.32816775 Up 0.318054459 Senp1 SUMO1/sentrin specific peptidase 1 K08592|1|0.0|1150|mmu:223870|sentrin-specific protease 1 [EC:3.4.22.68] - - - - 56743 1636 1.123333333 1.553333333 0.467581363 Up 0.317809997 Lat2 "linker for activation of T cells family, member 2" - GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464 GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding GO:0002279;GO:0019932//second-messenger-mediated signaling;GO:0046649//lymphocyte activation;GO:0050851//antigen receptor-mediated signaling pathway;GO:0002279;GO:0019932//second-messenger-mediated signaling;GO:0046649//lymphocyte activation;GO:0050851//antigen receptor-mediated signaling pathway gi|45496830|ref|NP_075253.2|/1.98704e-94/linker for activation of T-cells family member 2 isoform b precursor [Mus musculus] 74199 2737 1.116666667 1.55 0.473069621 Up 0.317809997 Vit vitrin "K06238|1|3e-52|209|pss:102454802|collagen, type VI, alpha" GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix - GO:0043062//extracellular structure organization;GO:0010810//regulation of cell-substrate adhesion;GO:0043062//extracellular structure organization;GO:0010810//regulation of cell-substrate adhesion gi|308081588|ref|NP_001183957.1|/0/vitrin isoform 2 [Mus musculus] 226541 4037 4.853333333 4.106666667 -0.2410081 Down 0.317772387 Klhl20 kelch-like 20 K10457|1|0.0|1244|nle:100601692|kelch-like protein 20 GO:0005856//cytoskeleton;GO:0016604//nuclear body;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0044444//cytoplasmic part GO:0008092//cytoskeletal protein binding;GO:0019961;GO:0019787//ubiquitin-like protein transferase activity GO:0006996//organelle organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0034097//response to cytokine gi|60360602|dbj|BAD90319.1|/0/mKIAA4210 protein [Mus musculus] 20646 1970.73 56.86 62.26 0.130891478 Up 0.317753582 Snrpn small nuclear ribonucleoprotein N K11100|1|6e-64|248|cjc:103787208|small nuclear ribonucleoprotein N GO:0030532//small nuclear ribonucleoprotein complex;GO:0030532//small nuclear ribonucleoprotein complex;GO:0030532//small nuclear ribonucleoprotein complex GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0009719;GO:0006396//RNA processing;GO:0009719;GO:0006396//RNA processing;GO:0009719;GO:0006396//RNA processing gi|675690021|ref|XP_009004277.1|/5.11982e-63/PREDICTED: small nuclear ribonucleoprotein-associated protein N isoform X2 [Callithrix jacchus] 330177 4303.65 3.016666667 2.436666667 -0.308046386 Down 0.317697168 Taok3 TAO kinase 3 K04429|1|0.0|1578|mmu:330177|thousand and one amino acid protein kinase [EC:2.7.11.1] GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004672//protein kinase activity;GO:0019887//protein kinase regulator activity;GO:0032550;GO:0004672//protein kinase activity;GO:0019887//protein kinase regulator activity;GO:0032550;GO:0004672//protein kinase activity;GO:0019887//protein kinase regulator activity GO:0032872//regulation of stress-activated MAPK cascade;GO:0006259//DNA metabolic process;GO:0007254//JNK cascade;GO:0001933//negative regulation of protein phosphorylation;GO:0000077//DNA damage checkpoint;GO:0043406//positive regulation of MAP kinase activity;GO:0032872//regulation of stress-activated MAPK cascade;GO:0006259//DNA metabolic process;GO:0007254//JNK cascade;GO:0001933//negative regulation of protein phosphorylation;GO:0000077//DNA damage checkpoint;GO:0043406//positive regulation of MAP kinase activity;GO:0032872//regulation of stress-activated MAPK cascade;GO:0006259//DNA metabolic process;GO:0007254//JNK cascade;GO:0001933//negative regulation of protein phosphorylation;GO:0000077//DNA damage checkpoint;GO:0043406//positive regulation of MAP kinase activity gi|124486801|ref|NP_001074777.1|/0/serine/threonine-protein kinase TAO3 [Mus musculus] 17532 4058 2.396666667 2.976666667 0.312668405 Up 0.317697168 Mras muscle and microspikes RAS K07831|1|3e-102|376|mmu:17532|Ras-related protein M-Ras GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding GO:0009154//purine ribonucleotide catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0007010//cytoskeleton organization;GO:0048513//animal organ development gi|6678930|ref|NP_032650.1|/2.89472e-101/ras-related protein M-Ras precursor [Mus musculus] 52662 2493 2.403333333 2.983333333 0.311888423 Up 0.317697168 Ldlrad4 low density lipoprotein receptor class A domain containing 4 - GO:0031224//intrinsic component of membrane - - gi|31324575|ref|NP_766219.2|/1.73721e-175/low-density lipoprotein receptor class A domain-containing protein 4 [Mus musculus] 71853 2125 27.88666667 30.7 0.138663158 Up 0.317687766 Pdia6 protein disulfide isomerase associated 6 K09584|1|0.0|827|mmu:71853|protein disulfide-isomerase A6 [EC:5.3.4.1] - - - - 55979 2165.26 56.02 61.4 0.132296672 Up 0.317687766 Agpat1 "1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)" K13509|1|2e-154|548|mmu:55979|lysophosphatidate acyltransferase [EC:2.3.1.51] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0016411//acylglycerol O-acyltransferase activity;GO:0016411//acylglycerol O-acyltransferase activity GO:0046473//phosphatidic acid metabolic process;GO:0001816//cytokine production;GO:0046473//phosphatidic acid metabolic process;GO:0001816//cytokine production gi|254281341|ref|NP_001156851.1|/1.37832e-153/1-acyl-sn-glycerol-3-phosphate acyltransferase alpha precursor [Mus musculus] 14148 1337.24 29.69666667 26.89 -0.143231248 Down 0.317687766 Fdx1 ferredoxin 1 K02516|1|8e-23|110|tsp:Tsp_08085|type II protein arginine methyltransferase [EC:2.1.1.320] GO:0005743//mitochondrial inner membrane;GO:0005743//mitochondrial inner membrane GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0005515//protein binding;GO:0008395//steroid hydroxylase activity;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0005515//protein binding;GO:0008395//steroid hydroxylase activity GO:0035270//endocrine system development;GO:0055114//oxidation-reduction process;GO:0006091//generation of precursor metabolites and energy;GO:0071870//cellular response to catecholamine stimulus;GO:0032870//cellular response to hormone stimulus;GO:0051234//establishment of localization;GO:0043085//positive regulation of catalytic activity;GO:0035270//endocrine system development;GO:0055114//oxidation-reduction process;GO:0006091//generation of precursor metabolites and energy;GO:0071870//cellular response to catecholamine stimulus;GO:0032870//cellular response to hormone stimulus;GO:0051234//establishment of localization;GO:0043085//positive regulation of catalytic activity "gi|683524007|ref|NP_001288657.1|/3.4162e-82/adrenodoxin, mitochondrial isoform 2 precursor [Mus musculus]" 208795 3239 9.206666667 10.40333333 0.176295038 Up 0.317574937 Tmem63a transmembrane protein 63a K10165|1|1e-37|161|cjc:100414962|nucleotide-binding oligomerization domain-containing protein 2 GO:0005764//lysosome;GO:0031224//intrinsic component of membrane - - "gi|148681191|gb|EDL13138.1|/0/transmembrane protein 63a, isoform CRA_a, partial [Mus musculus]" 242406 5868 15.14666667 13.53 -0.162838495 Down 0.317574937 Rgp1 RAB6A GEF compex partner 1 K20477|1|0.0|665|rno:313493|RAB6A-GEF complex partner protein 2 - - - gi|37359870|dbj|BAC97913.1|/0/mKIAA0258 protein [Mus musculus] 100861908 1863 0.386666667 0.71 0.876728625 Up 0.317527925 Gm21319 "predicted gene, 21319" K03236|1|1e-49|200|ngi:103727416|translation initiation factor 1A - "GO:0008135//translation factor activity, RNA binding" GO:0006412//translation gi|398303830|ref|NP_001257651.1|/9.03449e-54/eukaryotic translation initiation factor 1A-like [Mus musculus] 20198 513 4.46 3.746666667 -0.25143608 Down 0.317527925 S100a4 S100 calcium binding protein A4 K17274|1|6e-07|55.5|asn:102383833|calpactin-1 light chain GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0042995//cell projection GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0005102//receptor binding GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|33859624|ref|NP_035441.1|/8.38381e-41/protein S100-A4 [Mus musculus] 211535 2453 0.7 0.38 -0.881355504 Down 0.317527925 Ccdc114 coiled-coil domain containing 114 K18626|1|2e-07|60.8|myd:102770051|trichohyalin;K11498|2|9e-07|58.5|mde:101887902|centromeric protein E;K20478|3|1e-06|57.8|dre:557772|golgin subfamily B member 1;K20045|5|2e-06|57.4|dre:566412|intersectin GO:0005858//axonemal dynein complex - GO:0070286//axonemal dynein complex assembly gi|568947630|ref|XP_006540834.1|/0/PREDICTED: coiled-coil domain-containing protein 114 isoform X5 [Mus musculus] 78787 6495 6.873333333 5.96 -0.205697596 Down 0.317480913 Usp54 ubiquitin specific peptidase 54 "K14206|1|2e-30|138|dpe:Dper_GL26826|solute carrier family 15 (oligopeptide transporter), member 1;K11366|2|4e-06|57.8|tad:TRIADDRAFT_52906|ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]" - GO:0016790//thiolester hydrolase activity GO:0019941//modification-dependent protein catabolic process gi|124053453|ref|NP_084456.2|/0/inactive ubiquitin carboxyl-terminal hydrolase 54 [Mus musculus] 67283 2492.41 12.53666667 11.17666667 -0.165663823 Down 0.317433901 Slc25a19 "solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19" "K15108|1|1e-180|636|mmu:67283|solute carrier family 25 (mitochondrial thiamine pyrophosphate transporter), member 19" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763 gi|21313024|ref|NP_080347.1|/9.54375e-180/mitochondrial thiamine pyrophosphate carrier isoform 1 [Mus musculus] 230316 3062 0.82 0.48 -0.772589504 Down 0.317424499 Megf9 multiple EGF-like-domains 9 "K06243|1|3e-53|213|cjo:107319878|laminin, beta 2" GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding - gi|27370004|ref|NP_766282.1|/0/multiple epidermal growth factor-like domains protein 9 precursor [Mus musculus] 231727 1423 1.913333333 2.433333333 0.346845727 Up 0.317415096 B3gnt4 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4" "K07971|1|0.0|681|mmu:231727|beta-1,3-N-acetylglucosaminyltransferase 4 [EC:2.4.1.-]" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0016758//transferase activity, transferring hexosyl groups" GO:0006464//cellular protein modification process "gi|755513657|ref|XP_011246501.1|/0/PREDICTED: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 isoform X2 [Mus musculus]" 66632 2700 2.923333333 3.55 0.280204683 Up 0.317405694 Dph6 diphthamine biosynthesis 6 K06927|1|7e-133|477|mmu:66632|diphthine-ammonia ligase [EC:6.3.1.14] - GO:0016881//acid-amino acid ligase activity;GO:0032550 GO:0017182 gi|13385136|ref|NP_079951.1|/5.81333e-132/diphthine--ammonia ligase [Mus musculus] 66904 2306 62.65333333 57.43333333 -0.125502971 Down 0.317274061 Pccb "propionyl Coenzyme A carboxylase, beta polypeptide" K01966|1|0.0|1054|mmu:66904|propionyl-CoA carboxylase beta chain [EC:6.4.1.3] - - - - 227290 1817.6 55.72666667 60.93666667 0.128942724 Up 0.317264658 Aamp angio-associated migratory protein K14818|1|3e-178|627|gga:769880|ribosome assembly protein SQT1 GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0044424 GO:0005539//glycosaminoglycan binding;GO:0005539//glycosaminoglycan binding GO:0048646//anatomical structure formation involved in morphogenesis;GO:0010594//regulation of endothelial cell migration;GO:0014812//muscle cell migration;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0010594//regulation of endothelial cell migration;GO:0014812//muscle cell migration gi|880972802|ref|XP_005088107.2|/0/PREDICTED: angio-associated migratory cell protein isoform X1 [Mesocricetus auratus] 66736 1245 58.91333333 53.7 -0.133672095 Down 0.317264658 Emc2 ER membrane protein complex subunit 2 - GO:0030176//integral component of endoplasmic reticulum membrane - - gi|13385196|ref|NP_080012.1|/3.76457e-161/ER membrane protein complex subunit 2 [Mus musculus] 246787 2259 1.286666667 1.736666667 0.432682525 Up 0.317255256 Slc5a2 "solute carrier family 5 (sodium/glucose cotransporter), member 2" "K14382|1|0.0|1172|mmu:246787|solute carrier family 5 (sodium/glucose cotransporter), member 2" GO:0005903//brush border;GO:0031224//intrinsic component of membrane GO:0005355//glucose transmembrane transporter activity;GO:0005488//binding;GO:0015291//secondary active transmembrane transporter activity GO:0044763;GO:0008645//hexose transport;GO:0030001//metal ion transport gi|18875434|ref|NP_573517.1|/0/sodium/glucose cotransporter 2 [Mus musculus] 64602 5808 3.833333333 3.18 -0.26957269 Down 0.317255256 Ireb2 iron responsive element binding protein 2 K01681|1|0.0|1122|spu:586198|aconitate hydratase [EC:4.2.1.3] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding;GO:0003729//mRNA binding GO:0006779//porphyrin-containing compound biosynthetic process;GO:0006412//translation;GO:0002573//myeloid leukocyte differentiation;GO:0010039//response to iron ion;GO:0001666//response to hypoxia;GO:0048872//homeostasis of number of cells;GO:0033993//response to lipid;GO:0022600//digestive system process;GO:0006875//cellular metal ion homeostasis "gi|148693883|gb|EDL25830.1|/0/iron responsive element binding protein 2, isoform CRA_a, partial [Mus musculus]" 223267 1079 13.93 15.54 0.157791246 Up 0.317236451 Ggact gamma-glutamylamine cyclotransferase K19761|1|1e-87|325|mmu:223267|gamma-glutamylaminecyclotransferase [EC:2.3.2.-] - "GO:0016755//transferase activity, transferring amino-acyl groups" GO:0006575//cellular modified amino acid metabolic process "gi|148668302|gb|EDL00632.1|/4.73956e-90/cDNA sequence BC006662, isoform CRA_a [Mus musculus]" 71693 1436.17 14.99 13.37666667 -0.164281728 Down 0.317236451 Colec11 collectin sub-family member 11 K10066|1|2e-128|461|mmu:71693|collectin sub-family member 11 - - - - 74684 2831 0.38 0.696666667 0.874469118 Up 0.317217646 4930451G09Rik RIKEN cDNA 4930451G09 gene - - - - gi|409191599|ref|NP_001258515.1|/0/uncharacterized protein LOC74684 [Mus musculus] 27029 4324 2.496666667 3.083333333 0.304487647 Up 0.317189439 Sgsh N-sulfoglucosamine sulfohydrolase (sulfamidase) K01565|1|0.0|1031|mmu:27029|N-sulfoglucosamine sulfohydrolase [EC:3.10.1.1] GO:0000323//lytic vacuole "GO:0016788//hydrolase activity, acting on ester bonds;GO:0016826" GO:0006029//proteoglycan metabolic process "gi|148702751|gb|EDL34698.1|/0/N-sulfoglucosamine sulfohydrolase (sulfamidase), isoform CRA_d, partial [Mus musculus]" 80837 2358 27.35333333 30.11 0.138526055 Up 0.317170634 Rhoj ras homolog family member J "K07864|1|8e-114|414|mmu:80837|Ras homolog gene family, member J" GO:0016020//membrane;GO:0044444//cytoplasmic part GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0007010//cytoskeleton organization;GO:0007265//Ras protein signal transduction;GO:0022604//regulation of cell morphogenesis;GO:0009154//purine ribonucleotide catabolic process "gi|148704543|gb|EDL36490.1|/1.22794e-114/ras homolog gene family, member J, isoform CRA_b, partial [Mus musculus]" 97130 5007.32 2.54 2.013333333 -0.335242448 Down 0.317067208 C77080 expressed sequence C77080 - - - - gi|551894605|ref|NP_001272795.1|/0/uncharacterized protein KIAA1522 isoform c [Mus musculus] 101502 1812.69 9.123333333 10.31 0.176411399 Up 0.317048403 Hsd3b7 "hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7" "K12408|1|0.0|655|mmu:101502|cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase [EC:1.1.1.181]" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0016049//cell growth;GO:0008202//steroid metabolic process;GO:0016049//cell growth;GO:0008202//steroid metabolic process gi|100817045|ref|NP_598704.2|/2.01259e-172/3 beta-hydroxysteroid dehydrogenase type 7 isoform a [Mus musculus] 18755 3546 12.28666667 10.93333333 -0.168360256 Down 0.317029599 Prkch "protein kinase C, eta" K18051|1|0.0|1415|mmu:18755|novel protein kinase C eta type [EC:2.7.11.13] - - - - 76604 620 0.01 0.166666667 4.058893689 Up 0.316982587 1700047A11Rik RIKEN cDNA 1700047A11 gene K13295|1|1e-10|68.6|dre:100126009|aprataxin and PNK-like factor [EC:4.2.99.18];K04001|4|5e-06|53.1|pss:102463420|C1 inhibitor - - - - 67182 826 0.01 0.166666667 4.058893689 Up 0.316982587 Pdzk1ip1 PDZK1 interacting protein 1 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|257095992|ref|NP_001158029.1|/1.26806e-64/PDZK1-interacting protein 1 isoform 1 [Mus musculus] 69189 1132 0.01 0.166666667 4.058893689 Up 0.316982587 Mcemp1 mast cell expressed membrane protein 1 K20280|1|7e-23|110|myb:102241631|trafficking protein particle complex subunit 5;K13438|2|2e-09|66.2|shr:100925161|resistin GO:0031224//intrinsic component of membrane - - gi|109659834|ref|NP_081261.1|/2.99033e-98/mast cell-expressed membrane protein 1 [Mus musculus] 75951 907 0.01 0.166666667 4.058893689 Up 0.316982587 4930578M01Rik RIKEN cDNA 4930578M01 gene - - - - - 239435 1360 0.01 0.166666667 4.058893689 Up 0.316982587 Aard alanine and arginine rich domain containing protein - - - - gi|149066401|gb|EDM16274.1|/5.01988e-61/alanine and arginine rich domain containing protein [Rattus norvegicus] 13494 1524 27.50333333 30.24333333 0.137010678 Up 0.316973184 Drg1 developmentally regulated GTP binding protein 1 K06944|1|9e-107|389|bmor:101739147|uncharacterized protein GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0030529//intracellular ribonucleoprotein complex GO:0032550;GO:0005515//protein binding GO:0010467//gene expression;GO:0032502//developmental process gi|625259038|ref|XP_007620926.1|/0/PREDICTED: developmentally-regulated GTP-binding protein 1 [Cricetulus griseus] 14635 1506 6.743333333 7.72 0.195138933 Up 0.316935575 Galk1 galactokinase 1 K00849|1|0.0|721|mmu:14635|galactokinase [EC:2.7.1.6] GO:0044424 "GO:0048029//monosaccharide binding;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032550" GO:0006059//hexitol metabolic process;GO:0016310//phosphorylation;GO:0019318//hexose metabolic process gi|93102413|ref|NP_058601.2|/0/galactokinase [Mus musculus] 114601 5984.97 59.31333333 54.21666667 -0.129620035 Down 0.316926172 Ehbp1l1 EH domain binding protein 1-like 1 K19948|1|1e-118|431|ocu:100355512|MICAL-like protein - - - gi|167736351|ref|NP_001108069.1|/0/EH domain-binding protein 1-like protein 1 isoform a [Mus musculus] 13014 620 13.86333333 15.46666667 0.15788812 Up 0.316897965 Cstb cystatin B K13907|1|2e-50|200|mmu:13014|cystatin-A/B GO:0031981//nuclear lumen GO:0019899//enzyme binding;GO:0004866//endopeptidase inhibitor activity GO:0010466//negative regulation of peptidase activity;GO:0007626//locomotory behavior;GO:0006915//apoptotic process gi|6681071|ref|NP_031819.1|/1.78003e-49/cystatin-B [Mus musculus] 74412 3138 13.33666667 14.93666667 0.163460098 Up 0.316897965 Gle1 GLE1 RNA export mediator (yeast) K18723|1|0.0|1207|mmu:74412|nucleoporin GLE1 GO:0005635//nuclear envelope - GO:0006406//mRNA export from nucleus;GO:0045184//establishment of protein localization gi|58037369|ref|NP_083199.1|/0/nucleoporin GLE1 [Mus musculus] 100534633 460 0.346666667 0.103333333 -1.746243408 Down 0.316860356 Gm15008 predicted gene 15008 - - - - - 56517 2297 0.103333333 0.346666667 1.746243408 Up 0.316860356 Slc22a21 "solute carrier family 22 (organic cation transporter), member 21" "K08202|1|0.0|1048|mmu:56517|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 4/5" GO:0031224//intrinsic component of membrane;GO:0005903//brush border;GO:0044459;GO:0005778//peroxisomal membrane GO:0032550;GO:0015101//organic cation transmembrane transporter activity;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0019904//protein domain specific binding;GO:0015291//secondary active transmembrane transporter activity;GO:0019534//toxin transporter activity GO:0032846;GO:0006577//amino-acid betaine metabolic process;GO:0030001//metal ion transport;GO:0015695//organic cation transport;GO:0003006//developmental process involved in reproduction;GO:0007507//heart development;GO:0015893//drug transport;GO:0051701//interaction with host;GO:0006996//organelle organization;GO:0044708//single-organism behavior gi|9790131|ref|NP_062697.1|/0/solute carrier family 22 member 21 [Mus musculus] 74776 1383 56.75666667 51.69666667 -0.134718602 Down 0.316803941 Ppa2 pyrophosphatase (inorganic) 2 K01507|1|0.0|650|mmu:74776|inorganic pyrophosphatase [EC:3.6.1.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016462//pyrophosphatase activity;GO:0043169//cation binding;GO:0016462//pyrophosphatase activity;GO:0043169//cation binding GO:0006793//phosphorus metabolic process;GO:0006793//phosphorus metabolic process "gi|22203753|ref|NP_666253.1|/0/inorganic pyrophosphatase 2, mitochondrial isoform 1 precursor [Mus musculus]" 67252 3673 55.22 60.25666667 0.125929979 Up 0.31675693 Cap2 "CAP, adenylate cyclase-associated protein, 2 (yeast)" K17261|1|0.0|842|mmu:67252|adenylyl cyclase-associated protein GO:0016020//membrane GO:0008092//cytoskeletal protein binding GO:0007010//cytoskeleton organization;GO:0032989 "gi|148709080|gb|EDL41026.1|/0/CAP, adenylate cyclase-associated protein, 2 (yeast), isoform CRA_b, partial [Mus musculus]" 12447 2022 0.56 0.913333333 0.70571466 Up 0.316691113 Ccne1 cyclin E1 K06626|1|0.0|750|mmu:12447|cyclin E GO:0031981//nuclear lumen;GO:0005815//microtubule organizing center;GO:0043234//protein complex "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019887//protein kinase regulator activity;GO:0019900//kinase binding" GO:0007166//cell surface receptor signaling pathway;GO:0001541//ovarian follicle development;GO:0010243//response to organonitrogen compound;GO:0043627//response to estrogen;GO:0006259//DNA metabolic process;GO:0051384//response to glucocorticoid;GO:0051726//regulation of cell cycle;GO:0009887//organ morphogenesis;GO:0030154//cell differentiation;GO:0006464//cellular protein modification process;GO:0097305//response to alcohol;GO:0007584//response to nutrient gi|443940|emb|CAA53482.1|/0/cyclin E [Mus musculus] 16911 1700.17 18.52 20.49666667 0.146305207 Up 0.316634699 Lmo4 LIM domain only 4 K15612|1|2e-30|136|bfo:BRAFLDRAFT_232718|rhombotin-2 GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding GO:0014020;GO:0006366//transcription from RNA polymerase II promoter;GO:0006461//protein complex assembly;GO:0001708//cell fate specification;GO:0048534//hematopoietic or lymphoid organ development;GO:0001775//cell activation;GO:0003231//cardiac ventricle development;GO:0021515//cell differentiation in spinal cord;GO:0014020;GO:0006366//transcription from RNA polymerase II promoter;GO:0006461//protein complex assembly;GO:0001708//cell fate specification;GO:0048534//hematopoietic or lymphoid organ development;GO:0001775//cell activation;GO:0003231//cardiac ventricle development;GO:0021515//cell differentiation in spinal cord;GO:0014020;GO:0006366//transcription from RNA polymerase II promoter;GO:0006461//protein complex assembly;GO:0001708//cell fate specification;GO:0048534//hematopoietic or lymphoid organ development;GO:0001775//cell activation;GO:0003231//cardiac ventricle development;GO:0021515//cell differentiation in spinal cord gi|537243320|gb|ERE87669.1|/3.50254e-97/LIM domain transcription factor LMO4.2-like protein [Cricetulus griseus] 50753 3527 13.38 14.97333333 0.162317311 Up 0.316568882 Fbxo8 F-box protein 8 K10294|1|1e-177|626|mmu:50753|F-box protein 8 - - - gi|6164735|gb|AAF04517.1|AF174596_1/3.26963e-178/F-box protein Fbx8 [Homo sapiens] 100689 2237 0.486666667 0.826666667 0.764371752 Up 0.316559479 Spon2 "spondin 2, extracellular matrix protein" K06532|1|8e-23|111|dpe:Dper_GL10630|prominin 1 GO:0031012//extracellular matrix GO:0043169//cation binding GO:0006952//defense response;GO:0022610 gi|254939623|ref|NP_598664.3|/0/spondin-2 precursor [Mus musculus] 216166 2112 0.82 0.483333333 -0.762605415 Down 0.316559479 Plk5 polo-like kinase 5 K19596|1|0.0|1145|mmu:216166|inactive serine/threonine-protein kinase PLK5 GO:0031981//nuclear lumen GO:0032550;GO:0004672//protein kinase activity;GO:0043169//cation binding GO:0070848//response to growth factor;GO:1901990//regulation of mitotic cell cycle phase transition;GO:0008283//cell proliferation;GO:0010975//regulation of neuron projection development;GO:0000077//DNA damage checkpoint;GO:0002347//response to tumor cell;GO:0006464//cellular protein modification process gi|65508357|ref|NP_898975.2|/0/inactive serine/threonine-protein kinase PLK5 [Mus musculus] 16427 3044 1.21 0.823333333 -0.555458506 Down 0.316550077 Itih4 "inter alpha-trypsin inhibitor, heavy chain 4" K19014|1|4e-143|511|mdo:100619001|inter-alpha-trypsin inhibitor heavy chain H1 GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0044424 GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0004866//endopeptidase inhibitor activity;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0004866//endopeptidase inhibitor activity;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0004866//endopeptidase inhibitor activity;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0004866//endopeptidase inhibitor activity GO:0002526//acute inflammatory response;GO:0010033//response to organic substance;GO:0051346//negative regulation of hydrolase activity;GO:0030203//glycosaminoglycan metabolic process;GO:0002526//acute inflammatory response;GO:0010033//response to organic substance;GO:0051346//negative regulation of hydrolase activity;GO:0030203//glycosaminoglycan metabolic process;GO:0002526//acute inflammatory response;GO:0010033//response to organic substance;GO:0051346//negative regulation of hydrolase activity;GO:0030203//glycosaminoglycan metabolic process;GO:0002526//acute inflammatory response;GO:0010033//response to organic substance;GO:0051346//negative regulation of hydrolase activity;GO:0030203//glycosaminoglycan metabolic process "gi|148692824|gb|EDL24771.1|/0/inter alpha-trypsin inhibitor, heavy chain 4, isoform CRA_d, partial [Mus musculus]" 100039123 1324 4 4.74 0.244887059 Up 0.316437248 Gm14295 predicted gene 14295 K09228|1|1e-30|136|mmu:665211|KRAB domain-containing zinc finger protein - - - "gi|62201454|gb|AAH92392.1|/5.55825e-33/OTTMUSG00000016325 protein, partial [Mus musculus]" 67131 2081 9.126666667 10.30666667 0.175417873 Up 0.316418444 Acbd4 acyl-Coenzyme A binding domain containing 4 "K08762|1|4e-12|75.9|shr:105749269|diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein);K13239|2|6e-12|75.5|umr:103664953|peroxisomal 3,2-trans-enoyl-CoA isomerase [EC:5.3.3.8]" - GO:0005488//binding - "gi|148702224|gb|EDL34171.1|/1.77032e-170/acyl-Coenzyme A binding domain containing 4, isoform CRA_b, partial [Mus musculus]" 231724 1593 0.623333333 0.986666667 0.662558906 Up 0.31628681 Rad9b RAD9 checkpoint clamp component B K10995|1|0.0|802|mmu:231724|cell cycle checkpoint control protein RAD9B GO:0000794//condensed nuclear chromosome - GO:0006259//DNA metabolic process;GO:0006974//cellular response to DNA damage stimulus gi|568937151|ref|XP_006530368.1|/0/PREDICTED: cell cycle checkpoint control protein RAD9B isoform X1 [Mus musculus] 218772 2939.43 3.716666667 4.416666667 0.24894865 Up 0.316249201 Rarb "retinoic acid receptor, beta" K08528|1|0.0|808|mdo:100024675|retinoic acid receptor beta GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0042974//retinoic acid receptor binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0042974//retinoic acid receptor binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0042974//retinoic acid receptor binding;GO:0003677//DNA binding" GO:0002062//chondrocyte differentiation;GO:0051093//negative regulation of developmental process;GO:0055007//cardiac muscle cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0048562//embryonic organ morphogenesis;GO:0009755//hormone-mediated signaling pathway;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0030326//embryonic limb morphogenesis;GO:0048565//digestive tract development;GO:0035295//tube development;GO:0003416//endochondral bone growth;GO:0030522//intracellular receptor signaling pathway;GO:0042552//myelination;GO:0021544//subpallium development;GO:0030182//neuron differentiation;GO:0002062//chondrocyte differentiation;GO:0051093//negative regulation of developmental process;GO:0006366//transcription from RNA polymerase II promoter;GO:0055007//cardiac muscle cell differentiation;GO:0048562//embryonic organ morphogenesis;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0030326//embryonic limb morphogenesis;GO:0007154//cell communication;GO:0048565//digestive tract development;GO:0035295//tube development;GO:0003416//endochondral bone growth;GO:0021544//subpallium development;GO:0002062//chondrocyte differentiation;GO:0051093//negative regulation of developmental process;GO:0055007//cardiac muscle cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0048562//embryonic organ morphogenesis;GO:0009755//hormone-mediated signaling pathway;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0030326//embryonic limb morphogenesis;GO:0048565//digestive tract development;GO:0035295//tube development;GO:0003416//endochondral bone growth;GO:0030522//intracellular receptor signaling pathway;GO:0042552//myelination;GO:0021544//subpallium development;GO:0030182//neuron differentiation;GO:0002062//chondrocyte differentiation;GO:0051093//negative regulation of developmental process;GO:0055007//cardiac muscle cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0048562//embryonic organ morphogenesis;GO:0009755//hormone-mediated signaling pathway;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0030326//embryonic limb morphogenesis;GO:0048565//digestive tract development;GO:0035295//tube development;GO:0003416//endochondral bone growth;GO:0030522//intracellular receptor signaling pathway;GO:0042552//myelination;GO:0021544//subpallium development;GO:0030182//neuron differentiation gi|612056542|ref|XP_001369887.2|/0/PREDICTED: retinoic acid receptor beta isoform X1 [Monodelphis domestica] 99003 8975 4.39 3.69 -0.250600123 Down 0.316249201 Qser1 glutamine and serine rich 1 K11661|1|2e-80|305|acs:100567271|helicase SRCAP [EC:3.6.4.-];K13123|3|6e-46|190|mze:101475087|G patch domain-containing protein 1 - - - gi|568918988|ref|XP_006500521.1|/0/PREDICTED: glutamine and serine-rich protein 1 isoform X1 [Mus musculus] 14423 3908 28.10333333 25.44666667 -0.143264573 Down 0.316192786 Galnt1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 K00710|1|0.0|1131|mmu:14423|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane GO:0046914//transition metal ion binding;GO:0008376//acetylgalactosaminyltransferase activity;GO:0046914//transition metal ion binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0006493//protein O-linked glycosylation;GO:0006493//protein O-linked glycosylation gi|667287162|ref|XP_008576394.1|/0/PREDICTED: polypeptide N-acetylgalactosaminyltransferase 1 isoform X2 [Galeopterus variegatus] 56048 2741.05 13.24333333 14.82333333 0.162603611 Up 0.316164579 Lgals8 "lectin, galactose binding, soluble 8" K06832|1|0.0|638|mmu:56048|galectin-8 GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0031294//lymphocyte costimulation;GO:0031294//lymphocyte costimulation;GO:0031294//lymphocyte costimulation;GO:0031294//lymphocyte costimulation;GO:0031294//lymphocyte costimulation gi|9256551|ref|NP_061374.1|/2.22856e-180/galectin-8 isoform 1 [Mus musculus] 18693 1990.47 13.79666667 15.38 0.156735755 Up 0.316164579 Pick1 protein interacting with C kinase 1 K11406|1|0.0|736|ocu:100356004|histone deacetylase 4/5 [EC:3.5.1.98];K20314|2|8e-13|78.2|xtr:100380075|arfaptin GO:0032991//macromolecular complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0017111//nucleoside-triphosphatase activity;GO:0019901//protein kinase binding;GO:0043169//cation binding;GO:0001664//G-protein coupled receptor binding" GO:0007186//G-protein coupled receptor signaling pathway;GO:0072657//protein localization to membrane;GO:0006886//intracellular protein transport;GO:0006812//cation transport;GO:0051259//protein oligomerization;GO:0007268//chemical synaptic transmission;GO:0006464//cellular protein modification process;GO:0009154//purine ribonucleotide catabolic process;GO:0032502//developmental process;GO:0035556//intracellular signal transduction gi|966969351|ref|XP_015005795.1|/0/PREDICTED: PRKCA-binding protein isoform X1 [Macaca mulatta] 30927 1589 1.216666667 1.653333333 0.442443657 Up 0.316145775 Snai3 snail family zinc finger 3 K09217|1|3e-176|620|mmu:30927|snail 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated" gi|7305643|ref|NP_038942.1|/2.20121e-175/zinc finger protein SNAI3 [Mus musculus] 71233 1227 0.163333333 0.42 1.362570079 Up 0.316117567 Enkur "enkurin, TRPC channel interacting protein" "K05039|1|1e-17|93.2|tru:105418191|solute carrier family 6 (neurotransmitter transporter, GABA) member 6/8/11/12/13" GO:0043231//intracellular membrane-bounded organelle GO:0019904//protein domain specific binding - gi|21313146|ref|NP_082004.1|/2.82758e-137/enkurin [Mus musculus] 66817 1943 1.07 0.696666667 -0.619070355 Down 0.316079958 Tmem170 transmembrane protein 170 - GO:0031224//intrinsic component of membrane - - "gi|148679569|gb|EDL11516.1|/4.24739e-70/DNA segment, Chr 8, Brigham & Women's Genetics 1414 expressed, partial [Mus musculus]" 68796 2762 26.44666667 29.09666667 0.13776799 Up 0.316079958 Tmem214 transmembrane protein 214 - GO:0031224//intrinsic component of membrane;GO:0005874//microtubule - - gi|31559970|ref|NP_653108.2|/0/transmembrane protein 214 [Mus musculus] 330173 945 1.046666667 0.68 -0.622195407 Down 0.316079958 2610524H06Rik RIKEN cDNA 2610524H06 gene K04676|1|4e-06|54.7|cge:100762264|mothers against decapentaplegic homolog 1 - - - gi|30841010|ref|NP_851420.1|/8.54167e-74/uncharacterized protein C12orf76 homolog precursor [Mus musculus] 18160 4065 9.8 8.626666667 -0.183978538 Down 0.31589191 Npr1 natriuretic peptide receptor 1 K12323|1|0.0|2006|mmu:18160|atrial natriuretic peptide receptor A [EC:4.6.1.2] GO:0031224//intrinsic component of membrane GO:0016301//kinase activity;GO:0032550;GO:0001653//peptide receptor activity;GO:0042277//peptide binding;GO:0016829//lyase activity;GO:0019900//kinase binding;GO:0009975//cyclase activity GO:0003018;GO:0006584//catecholamine metabolic process;GO:0008015//blood circulation;GO:0008285//negative regulation of cell proliferation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0006464//cellular protein modification process;GO:0006182//cGMP biosynthetic process gi|113930718|ref|NP_032753.5|/0/atrial natriuretic peptide receptor 1 precursor [Mus musculus] 67946 2454 5.346666667 4.566666667 -0.227498249 Down 0.315882508 Spata6 spermatogenesis associated 6 K12172|1|6e-40|168|cin:100180766|E3 SUMO-protein ligase RanBP2 - - GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|110347525|ref|NP_080746.3|/0/spermatogenesis-associated protein 6 precursor [Mus musculus] 17420 2505 4.576666667 5.356666667 0.227038304 Up 0.315882508 Mnat1 menage a trois 1 K10842|1|1e-163|579|mmu:17420|CDK-activating kinase assembly factor MAT1 GO:0005667//transcription factor complex "GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0042623//ATPase activity, coupled" GO:0006366//transcription from RNA polymerase II promoter;GO:0007507//heart development;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0007420//brain development;GO:0010038//response to metal ion;GO:0006464//cellular protein modification process;GO:0019222//regulation of metabolic process "gi|148704566|gb|EDL36513.1|/1.99933e-171/menage a trois 1, partial [Mus musculus]" 94213 2507 14.75 13.18 -0.162364584 Down 0.315835496 Ddx50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 K13183|1|0.0|1184|mmu:94213|ATP-dependent RNA helicase DDX50 [EC:3.6.4.13] GO:0016020//membrane;GO:0031981//nuclear lumen "GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550" - gi|16716475|ref|NP_444413.1|/0/ATP-dependent RNA helicase DDX50 [Mus musculus] 57441 995 29.23666667 26.62 -0.135268265 Down 0.315703862 Gmnn geminin K10749|1|1e-101|371|mmu:57441|geminin GO:0043231//intracellular membrane-bounded organelle GO:0000975//regulatory region DNA binding;GO:0019899//enzyme binding;GO:0008134//transcription factor binding "GO:0051726//regulation of cell cycle;GO:0006260//DNA replication;GO:0006351//transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0065003" gi|10181218|ref|NP_065592.1|/1.16643e-100/geminin [Mus musculus] 112419 3365 0.99 1.396666667 0.496487313 Up 0.31569446 Ifit1bl2 interferon induced protein with tetratricopeptide repeats 1B like 2 K14217|1|0.0|689|mmu:667373|interferon-induced protein with tetratricopeptide repeats 1 GO:0044424 GO:0005488//binding GO:0019079//viral genome replication;GO:0051095;GO:0043393//regulation of protein binding;GO:0034340//response to type I interferon;GO:0050687//negative regulation of defense response to virus;GO:0043330//response to exogenous dsRNA;GO:0035455//response to interferon-alpha;GO:0035456//response to interferon-beta gi|74315955|ref|NP_444447.1|/0/interferon induced protein with tetratricopeptide repeats 1B like 2 [Mus musculus] 626058 2827 2.64 3.236666667 0.293970865 Up 0.315685058 E330020D12Rik Riken cDNA E330020D12 gene - - - - - 93705 4645 0.403333333 0.726666667 0.849321088 Up 0.315666253 Pcdhgb8 "protocadherin gamma subfamily B, 8" K16496|1|0.0|1721|mmu:93705|protocadherin gamma subfamily B GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion "gi|18087745|ref|NP_291058.1|/0/protocadherin gamma subfamily B, 8 precursor [Mus musculus]" 17306 3247 0.443333333 0.773333333 0.80269856 Up 0.315628643 Sypl2 synaptophysin-like 2 K14168|1|2e-24|117|fpg:101912737|cytoplasmic tRNA 2-thiolation protein 1 [EC:2.7.7.-] GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0006875//cellular metal ion homeostasis gi|6678874|ref|NP_032622.1|/4.34328e-145/synaptophysin-like protein 2 [Mus musculus] 17084 997 3.076666667 3.713333333 0.27134668 Up 0.315487608 Ly86 lymphocyte antigen 86 - - - - - 70059 3185 3.133333333 3.776666667 0.269415199 Up 0.315487608 Degs2 "delta(4)-desaturase, sphingolipid 2" K04712|1|0.0|674|mmu:70059|sphingolipid Delta-4 desaturase [EC:1.14.-.-] - - - - 66701 1570 19.98 18.05333333 -0.146291345 Down 0.315478205 Spryd4 SPRY domain containing 4 K08285|1|3e-24|115|bfo:BRAFLDRAFT_218347|midline 1 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle - - gi|58037095|ref|NP_079992.1|/1.74483e-116/SPRY domain-containing protein 4 [Mus musculus] 11674 1520.51 3110.116667 3374.823333 0.117843282 Up 0.315421791 Aldoa "aldolase A, fructose-bisphosphate" "K01623|1|0.0|692|xla:100037142|fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0005856//cytoskeleton GO:0005515//protein binding;GO:0016832//aldehyde-lyase activity;GO:0048029//monosaccharide binding;GO:0005515//protein binding;GO:0016832//aldehyde-lyase activity;GO:0048029//monosaccharide binding;GO:0005515//protein binding;GO:0016832//aldehyde-lyase activity;GO:0048029//monosaccharide binding GO:0022604//regulation of cell morphogenesis;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006007//glucose catabolic process;GO:0006936//muscle contraction;GO:0019725//cellular homeostasis;GO:0022604//regulation of cell morphogenesis;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006007//glucose catabolic process;GO:0006936//muscle contraction;GO:0019725//cellular homeostasis;GO:0022604//regulation of cell morphogenesis;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006007//glucose catabolic process;GO:0006936//muscle contraction;GO:0048545//response to steroid hormone;GO:0019725//cellular homeostasis;GO:0006950//response to stress;GO:0051260//protein homooligomerization;GO:0002237//response to molecule of bacterial origin gi|293597567|ref|NP_001170778.1|/0/fructose-bisphosphate aldolase A isoform 1 precursor [Mus musculus] 29819 2824.6 27.85 25.24666667 -0.141584407 Down 0.315421791 Stau2 staufen (RNA binding protein) homolog 2 (Drosophila) K17597|1|0.0|1028|mmu:29819|double-stranded RNA-binding protein Staufen GO:0031981//nuclear lumen;GO:0015630//microtubule cytoskeleton;GO:0031981//nuclear lumen;GO:0015630//microtubule cytoskeleton GO:0003723//RNA binding;GO:0003723//RNA binding GO:0051234//establishment of localization;GO:0051234//establishment of localization gi|162287083|ref|NP_001104742.1|/0/double-stranded RNA-binding protein Staufen homolog 2 isoform 2 [Mus musculus] 100417829 4348 0.21 0.48 1.192645078 Up 0.315412389 Gm17757 "GTPase, very large interferon inducible 1 pseudogene" K06551|1|4e-10|70.5|xtr:101733039|signal-regulatory protein alpha/beta1/gamma;K12797|2|7e-08|63.2|mdo:100018349|caspase recruitment domain-containing protein 6 - - - gi|115270958|ref|NP_083276.2|/0/interferon-induced very large GTPase 1 [Mus musculus] 28010 1830 5.073333333 5.896666667 0.216965689 Up 0.315346572 Miip migration and invasion inhibitory protein - - - - gi|237681081|ref|NP_001020536.2|/0/migration and invasion-inhibitory protein [Mus musculus] 99889 2928.07 5.733333333 4.913333333 -0.22267204 Down 0.315346572 Arfip1 ADP-ribosylation factor interacting protein 1 K20314|1|0.0|658|mmu:99889|arfaptin GO:0012505//endomembrane system;GO:0044444//cytoplasmic part GO:0005515//protein binding GO:0009306//protein secretion gi|658309994|ref|NP_001280730.1|/0/arfaptin-1 isoform 2 [Mus musculus] 93836 4880 4.683333333 3.953333333 -0.244466121 Down 0.315318365 Rnf111 ring finger 111 K10635|1|0.0|1521|mmu:93836|E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27] GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0032183//SUMO binding;GO:0046872//metal ion binding;GO:0019787//ubiquitin-like protein transferase activity "GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016567//protein ubiquitination" gi|568962353|ref|XP_006511641.1|/0/PREDICTED: E3 ubiquitin-protein ligase Arkadia isoform X4 [Mus musculus] 231642 1148 0.92 1.316666667 0.517184386 Up 0.315318365 Alkbh2 "alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase" K10859|1|4e-129|463|mmu:231642|alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 [EC:1.14.11.-] - - - - 329562 2148.34 0.93 1.333333333 0.519734878 Up 0.315318365 A530013C23Rik RIKEN cDNA A530013C23 gene - - - - "gi|148674578|gb|EDL06525.1|/3.11058e-37/RIKEN cDNA A530013C23, isoform CRA_a [Mus musculus]" 11854 1338 3.08 2.503333333 -0.299079944 Down 0.315139719 Rhod ras homolog family member D "K07530|1|2e-113|411|mmu:11854|Ras homolog gene family, member D" GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0007265//Ras protein signal transduction;GO:0009154//purine ribonucleotide catabolic process gi|6671573|ref|NP_031511.1|/1.60148e-112/rho-related GTP-binding protein RhoD precursor [Mus musculus] 12869 383 1300.3 1195.19 -0.121604532 Down 0.315120915 Cox8b cytochrome c oxidase subunit VIIIb K02273|1|8e-26|117|mmu:12869|cytochrome c oxidase subunit 8 GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0042221//response to chemical;GO:0022904//respiratory electron transport chain "gi|6680995|ref|NP_031777.1|/7.3052e-25/cytochrome c oxidase subunit 8B, mitochondrial precursor [Mus musculus]" 14130 1423.87 7.616666667 8.66 0.185207266 Up 0.315092708 Fcgr2b "Fc receptor, IgG, low affinity IIb" K12560|1|8e-158|559|mmu:14130|low affinity immunoglobulin gamma Fc region receptor II-b;K16824|5|8e-92|340|mmu:14131|low affinity immunoglobulin gamma Fc region receptor II-c GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0043232;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0043232 GO:0004871//signal transducer activity;GO:0019865//immunoglobulin binding;GO:0004871//signal transducer activity;GO:0019865//immunoglobulin binding GO:0002683//negative regulation of immune system process;GO:0006909//phagocytosis;GO:0002274;GO:0001818//negative regulation of cytokine production;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0030888//regulation of B cell proliferation;GO:0002377//immunoglobulin production;GO:0002438//acute inflammatory response to antigenic stimulus;GO:0007165//signal transduction;GO:0002478;GO:0002237//response to molecule of bacterial origin;GO:0002683//negative regulation of immune system process;GO:0006909//phagocytosis;GO:0002274;GO:0001818//negative regulation of cytokine production;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0030888//regulation of B cell proliferation;GO:0002377//immunoglobulin production;GO:0002438//acute inflammatory response to antigenic stimulus;GO:0007165//signal transduction;GO:0002478;GO:0002237//response to molecule of bacterial origin gi|225384|prf||1301316A/0/macrophage lymphocyte receptor 210711 4171 7.49 8.526666667 0.18701614 Up 0.315092708 Mcmbp minichromosome maintenance complex binding protein K05700|1|9e-45|185|smm:Smp_170990|vinculin GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0005488//binding GO:0006260//DNA replication;GO:0007059//chromosome segregation;GO:0000087//mitotic M phase;GO:0051320 gi|22122389|ref|NP_666067.1|/0/mini-chromosome maintenance complex-binding protein [Mus musculus] 17761 3896.98 7.563333333 8.603333333 0.185873532 Up 0.315092708 Map7 microtubule-associated protein 7 K10433|1|7e-163|577|mmu:17761|microtubule-associated protein 7 GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane GO:0005515//protein binding;GO:0005515//protein binding GO:0033993//response to lipid;GO:0007009//plasma membrane organization;GO:0040007//growth;GO:0042592//homeostatic process;GO:0006664//glycolipid metabolic process;GO:0000226//microtubule cytoskeleton organization;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0006950//response to stress;GO:0033993//response to lipid;GO:0007009//plasma membrane organization;GO:0040007//growth;GO:0042592//homeostatic process;GO:0006664//glycolipid metabolic process;GO:0000226//microtubule cytoskeleton organization;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0006950//response to stress gi|310772196|ref|NP_001185564.1|/3.14602e-169/ensconsin isoform 2 [Mus musculus] 110911 8180.46 24.44333333 27.01333333 0.144230635 Up 0.3150645 Cds2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 K00981|1|7e-70|266|mmu:110911|phosphatidate cytidylyltransferase [EC:2.7.7.41] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0070567;GO:0070567;GO:0070567 GO:0046341//CDP-diacylglycerol metabolic process;GO:0007165//signal transduction;GO:0044723;GO:0046341//CDP-diacylglycerol metabolic process;GO:0007165//signal transduction;GO:0044723;GO:0046341//CDP-diacylglycerol metabolic process;GO:0007165//signal transduction;GO:0044723 gi|20149726|ref|NP_619592.1|/0/phosphatidate cytidylyltransferase 2 isoform a [Mus musculus] 100177 4427.99 2.056666667 1.58 -0.38038343 Down 0.315026891 Zmym6 "zinc finger, MYM-type 6" K09228|1|7e-47|192|gja:107122456|KRAB domain-containing zinc finger protein;K09503|2|2e-11|74.7|pss:102449121|DnaJ homolog subfamily A member 2;K04257|3|5e-09|67.0|cmy:102941531|olfactory receptor;K00933|4|2e-08|65.1|pss:102459236|creatine kinase [EC:2.7.3.2];K08835|5|3e-07|60.8|lcm:102350625|serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1] - GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0000902//cell morphogenesis;GO:0006996//organelle organization;GO:0000902//cell morphogenesis;GO:0006996//organelle organization;GO:0000902//cell morphogenesis;GO:0006996//organelle organization;GO:0000902//cell morphogenesis;GO:0006996//organelle organization;GO:0000902//cell morphogenesis;GO:0006996//organelle organization "gi|148698311|gb|EDL30258.1|/0/zinc finger, MYM-type 6, isoform CRA_a, partial [Mus musculus]" 70247 3256 53.36666667 48.83666667 -0.127974169 Down 0.314923465 Psmd1 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 1" K03032|1|0.0|1680|mmu:70247|26S proteasome regulatory subunit N2 GO:0031981//nuclear lumen;GO:0022624//proteasome accessory complex;GO:0044444//cytoplasmic part - "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0009894;GO:0006915//apoptotic process;GO:0044764;GO:0051320;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|664741947|ref|XP_008528275.1|/0/PREDICTED: 26S proteasome non-ATPase regulatory subunit 1 isoform X2 [Equus przewalskii] 67997 2228 5.35 4.576666667 -0.225241672 Down 0.314895257 Ddx59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 K19466|1|0.0|1149|mmu:67997|ATP-dependent RNA helicase DDX59 [EC:3.6.4.13] GO:0044464 "GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550" - gi|13385988|ref|NP_080776.1|/0/probable ATP-dependent RNA helicase DDX59 [Mus musculus] 402734 2640 0.116666667 0.36 1.625604485 Up 0.31486705 C730036E19Rik RIKEN cDNA C730036E19 gene - - - - "gi|148707527|gb|EDL39474.1|/2.07286e-41/mCG145603, partial [Mus musculus]" 320024 4394 53.13 48.62 -0.127976819 Down 0.31486705 Nceh1 neutral cholesterol ester hydrolase 1 K14349|1|0.0|764|mmu:320024|neutral cholesterol ester hydrolase 1 [EC:3.1.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0043168//anion binding;GO:0052689//carboxylic ester hydrolase activity GO:0006629//lipid metabolic process;GO:0006464//cellular protein modification process gi|50510901|dbj|BAD32436.1|/0/mKIAA1363 protein [Mus musculus] 14923 1098 50.78333333 46.27333333 -0.134174066 Down 0.31486705 Guk1 guanylate kinase 1 K00942|1|4e-111|403|rno:303179|guanylate kinase [EC:2.7.4.8] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part "GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0009152//purine ribonucleotide biosynthetic process;GO:0009153;GO:0009225//nucleotide-sugar metabolic process;GO:0015031//protein transport;GO:0009152//purine ribonucleotide biosynthetic process;GO:0009153;GO:0009225//nucleotide-sugar metabolic process;GO:0015031//protein transport gi|226874891|ref|NP_001152882.1|/4.55259e-112/guanylate kinase isoform 2 [Mus musculus] 22273 1665 907.96 832.9566667 -0.124387298 Down 0.314838843 Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 K00414|1|0.0|915|xla:100505438|ubiquinol-cytochrome c reductase core subunit 1 GO:0005746//mitochondrial respiratory chain GO:0043169//cation binding;GO:0005515//protein binding GO:0051234//establishment of localization;GO:0010243//response to organonitrogen compound;GO:0022904//respiratory electron transport chain "gi|46593021|ref|NP_079683.2|/0/cytochrome b-c1 complex subunit 1, mitochondrial precursor [Mus musculus]" 72654 845 46.53666667 51.01666667 0.132600762 Up 0.314773026 Ccdc12 coiled-coil domain containing 12 K12871|1|3e-75|283|mmu:72654|coiled-coil domain-containing protein 12 - - - gi|227496903|ref|NP_082588.2|/2.3991e-74/coiled-coil domain-containing protein 12 [Mus musculus] 212974 2975 1.95 2.473333333 0.342982562 Up 0.314697807 Athl1 "ATH1, acid trehalase-like 1 (yeast)" "K09657|1|4e-22|109|tgu:100218099|beta-1,4-N-acetylgalactosaminyltransferase 4 [EC:2.4.1.244]" - GO:0016787//hydrolase activity GO:0044238//primary metabolic process gi|47059095|ref|NP_663362.2|/0/acid trehalase-like protein 1 [Mus musculus] 77090 1652 9.836666667 8.69 -0.178813338 Down 0.3146696 Ocel1 occludin/ELL domain containing 1 K04942|1|4e-08|62.0|pss:102444244|potassium intermediate/small conductance calcium-activated channel subfamily N member 1;K17291|2|6e-08|61.6|amj:102575402|MARVEL domain-containing protein 2 - - - "gi|148696960|gb|EDL28907.1|/1.81223e-46/RIKEN cDNA 9430098E02, isoform CRA_a, partial [Mus musculus]" 24063 2241.23 24.34666667 26.89 0.143345491 Up 0.314631991 Spry1 sprouty homolog 1 (Drosophila) K04704|1|6e-138|494|mmu:24063|protein sprouty homolog 1 - GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007265//Ras protein signal transduction;GO:0008283//cell proliferation;GO:0003156//regulation of organ formation;GO:0043409//negative regulation of MAPK cascade;GO:0043405//regulation of MAP kinase activity;GO:0035295//tube development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0034260//negative regulation of GTPase activity;GO:0007265//Ras protein signal transduction;GO:0008283//cell proliferation;GO:0003156//regulation of organ formation;GO:0043409//negative regulation of MAPK cascade;GO:0043405//regulation of MAP kinase activity;GO:0035295//tube development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0034260//negative regulation of GTPase activity;GO:0007265//Ras protein signal transduction;GO:0008283//cell proliferation;GO:0003156//regulation of organ formation;GO:0043409//negative regulation of MAPK cascade;GO:0043405//regulation of MAP kinase activity;GO:0035295//tube development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0034260//negative regulation of GTPase activity;GO:0007265//Ras protein signal transduction;GO:0008283//cell proliferation;GO:0003156//regulation of organ formation;GO:0043409//negative regulation of MAPK cascade;GO:0043405//regulation of MAP kinase activity;GO:0035295//tube development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0034260//negative regulation of GTPase activity gi|6755650|ref|NP_036026.1|/4.59885e-137/protein sprouty homolog 1 [Mus musculus] 66414 561 718.5666667 782.4233333 0.122827383 Up 0.314613186 Ndufa12 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12" K11352|1|4e-80|298|mmu:66414|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12 GO:0005746//mitochondrial respiratory chain GO:0050136//NADH dehydrogenase (quinone) activity GO:0051234//establishment of localization;GO:0006950//response to stress;GO:0006091//generation of precursor metabolites and energy gi|27228985|ref|NP_079827.2|/2.81155e-79/NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 [Mus musculus] 106759 2852 10.16333333 11.45333333 0.172393886 Up 0.314603784 Ticam1 toll-like receptor adaptor molecule 1 K05842|1|0.0|1263|mmu:106759|toll-like receptor adapter molecule 1 GO:0031090//organelle membrane;GO:0044444//cytoplasmic part GO:0060089;GO:0019900//kinase binding GO:0007166//cell surface receptor signaling pathway;GO:0012501//programmed cell death;GO:0043393//regulation of protein binding;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0030888//regulation of B cell proliferation;GO:0042033//chemokine biosynthetic process;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006809//nitric oxide biosynthetic process;GO:0001819//positive regulation of cytokine production;GO:0002252;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0016567//protein ubiquitination;GO:0043331//response to dsRNA;GO:0002237//response to molecule of bacterial origin;GO:0042108//positive regulation of cytokine biosynthetic process "gi|22477609|gb|AAH37048.1|/0/Ticam1 protein, partial [Mus musculus]" 84506 410 0.383333333 0.133333333 -1.523561956 Down 0.314594381 Hamp hepcidin antimicrobial peptide - GO:0044448 - GO:0006952//defense response;GO:0006875//cellular metal ion homeostasis gi|148692030|gb|EDL23977.1|/1.69747e-34/mCG50445 [Mus musculus] 13629 3126 707.7866667 769.3233333 0.120275481 Up 0.314566174 Eef2 eukaryotic translation elongation factor 2 K03234|1|0.0|1670|xla:100505433|elongation factor 2 GO:0030529//intracellular ribonucleoprotein complex "GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008135//translation factor activity, RNA binding" GO:0006412//translation;GO:0009154//purine ribonucleotide catabolic process gi|33859482|ref|NP_031933.1|/0/elongation factor 2 [Mus musculus] 78304 518 47.95666667 52.38666667 0.127468283 Up 0.314547369 Naa38 "N(alpha)-acetyltransferase 38, NatC auxiliary subunit" K11086|1|9e-09|61.6|spu:581143|small nuclear ribonucleoprotein B and B' GO:0043231//intracellular membrane-bounded organelle - - "gi|58037525|ref|NP_084359.1|/1.00376e-52/N(alpha)-acetyltransferase 38, NatC auxiliary subunit [Mus musculus]" 69732 1407 1.39 1.846666667 0.409838593 Up 0.314547369 2410018L13Rik RIKEN cDNA 2410018L13 gene K19695|1|1e-22|110|xma:102223298|neurocalcin delta - - - - 243853 2817 25.3 27.83333333 0.137676312 Up 0.314528564 Fkrp fukutin related protein K19873|1|0.0|944|mmu:243853|fukutin-related protein [EC:2.-.-.-] GO:0044421;GO:0012505//endomembrane system;GO:0043234//protein complex;GO:0005886//plasma membrane;GO:0031224//intrinsic component of membrane;GO:0005783//endoplasmic reticulum GO:0003824//catalytic activity GO:0009100//glycoprotein metabolic process;GO:0051604//protein maturation gi|27734120|ref|NP_775606.1|/0/fukutin-related protein [Mus musculus] 216169 1473 25.34 27.87 0.137296478 Up 0.314528564 Abhd17a abhydrolase domain containing 17A K06889|1|6e-15|84.7|pxy:105384212|uncharacterized protein - GO:0003824//catalytic activity - gi|21703840|ref|NP_663396.1|/3.20475e-149/protein ABHD17A precursor [Mus musculus] 229709 3866 26.60666667 24.07666667 -0.144152108 Down 0.314528564 Ahcyl1 S-adenosylhomocysteine hydrolase-like 1 K01251|1|0.0|987|lve:103077044|adenosylhomocysteinase [EC:3.3.1.1] GO:0043231//intracellular membrane-bounded organelle GO:0016802;GO:0036094//small molecule binding GO:0022898//regulation of transmembrane transporter activity;GO:0006820//anion transport;GO:0002028//regulation of sodium ion transport;GO:0031124//mRNA 3'-end processing;GO:0006886//intracellular protein transport gi|148743914|gb|AAI42523.1|/0/AHCYL1 protein [Bos taurus] 19377 7317.01 7.383333333 6.436666667 -0.197958534 Down 0.314519162 Rai1 retinoic acid induced 1 K19749|1|0.0|3296|mmu:19377|retinoic acid-induced protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0035264//multicellular organism growth;GO:0006366//transcription from RNA polymerase II promoter;GO:0035264//multicellular organism growth;GO:0006366//transcription from RNA polymerase II promoter gi|83649745|ref|NP_001032853.1|/0/retinoic acid-induced protein 1 [Mus musculus] 223922 6868.37 6.45 7.4 0.19822611 Up 0.314519162 Atf7 activating transcription factor 7 K09045|1|0.0|671|mmu:223922|activating transcription factor 7 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0019901//protein kinase binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0019901//protein kinase binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0019901//protein kinase binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148672015|gb|EDL03962.1|/0/activating transcription factor 7, isoform CRA_c, partial [Mus musculus]" 280408 1510 47.40666667 51.83 0.128697438 Up 0.314500357 Rilp Rab interacting lysosomal protein K13883|1|8e-167|589|mmu:280408|Rab-interacting lysosomal protein GO:0005768//endosome;GO:0000323//lytic vacuole;GO:0031982//vesicle GO:0017016//Ras GTPase binding GO:0007041//lysosomal transport;GO:0045184//establishment of protein localization gi|71480154|ref|NP_001025109.1|/6.65103e-166/rab-interacting lysosomal protein [Mus musculus] 54219 2209.38 7.42 8.45 0.187532155 Up 0.314368724 Cd320 CD320 antigen K06734|1|1e-104|383|mmu:54219|CD320 antigen GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005102//receptor binding;GO:0019842//vitamin binding - gi|761631392|ref|NP_001292098.1|/1.29573e-118/CD320 antigen isoform 2 precursor [Mus musculus] 72201 3311 19.58666667 17.70666667 -0.145579249 Down 0.314340517 Otud6b OTU domain containing 6B K18342|1|2e-152|542|mmu:72201|OTU domain-containing protein 6 [EC:3.4.19.12] - - - gi|157364966|ref|NP_690025.2|/1.86371e-151/OTU domain-containing protein 6B [Mus musculus] 108670 1659 0.926666667 1.323333333 0.514054124 Up 0.31431231 Epsti1 epithelial stromal interaction 1 (breast) K10433|1|8e-09|64.3|myb:102255646|microtubule-associated protein 7;K16806|5|8e-08|60.8|amj:102562004|MAP7 domain-containing protein 1 - - - gi|30519881|ref|NP_083771.1|/2.01542e-178/epithelial-stromal interaction protein 1 isoform a [Mus musculus] 66320 791 13.01 14.54333333 0.160737011 Up 0.3142747 Tmem208 transmembrane protein 208 - GO:0031224//intrinsic component of membrane - - gi|884921478|ref|XP_013010435.1|/1.31892e-92/PREDICTED: transmembrane protein 208 [Cavia porcellus] 68631 1410 3.246666667 3.9 0.264514852 Up 0.314199481 Cryl1 "crystallin, lambda 1" K13247|1|4e-144|513|mmu:68631|L-gulonate 3-dehydrogenase [EC:1.1.1.45] GO:0044444//cytoplasmic part "GO:0042802//identical protein binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0043168//anion binding;GO:0048037//cofactor binding" GO:0032787//monocarboxylic acid metabolic process gi|19525729|ref|NP_084280.2|/3.21308e-143/lambda-crystallin homolog [Mus musculus] 13019 1401.47 3.293333333 3.943333333 0.259867127 Up 0.314199481 Ctf1 cardiotrophin 1 K05422|1|2e-88|328|mmu:13019|cardiotrophin 1 GO:0044421;GO:0044421;GO:0044421 GO:0005126//cytokine receptor binding;GO:0005126//cytokine receptor binding;GO:0005126//cytokine receptor binding GO:0030182//neuron differentiation;GO:0002376//immune system process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0030182//neuron differentiation;GO:0002376//immune system process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0030182//neuron differentiation;GO:0008283//cell proliferation;GO:0002376//immune system process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0048513//animal organ development gi|6681075|ref|NP_031821.1|/1.20514e-91/cardiotrophin-1 isoform 1 [Mus musculus] 12585 2525 3.306666667 3.953333333 0.257691984 Up 0.314199481 Cdr2 cerebellar degeneration-related 2 K20478|1|5e-08|62.8|ola:101162333|golgin subfamily B member 1;K10352|2|3e-07|60.1|myb:102245570|myosin heavy chain GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding - gi|161484625|ref|NP_031698.2|/0/cerebellar degeneration-related protein 2 [Mus musculus] 268465 2228 2.043333333 2.576666667 0.33458134 Up 0.314161871 Eme1 essential meiotic structure-specific endonuclease 1 K10882|1|0.0|1029|mmu:268465|crossover junction endonuclease EME1 [EC:3.1.22.-] - - - - 234725 4902 2.04 2.57 0.333199207 Up 0.314161871 Zfp612 zinc finger protein 612 K09228|1|0.0|1405|mmu:234725|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|283837868|ref|NP_780689.3|/0/zinc finger protein 23 [Mus musculus] 100039781 936 10.34666667 11.62333333 0.167857807 Up 0.314105457 Hrct1 histidine rich carboxyl terminus 1 - - - - gi|148233271|ref|NP_081787.1|/5.35584e-12/histidine-rich carboxyl terminus protein 1 [Mus musculus] 108176 986 0.18 0.44 1.289506617 Up 0.314049043 Npm3-ps1 "nucleoplasmin 3, pseudogene 1" K11278|1|1e-69|265|mmu:18150|nucleophosmin 3 - - - - 414758 3794.42 3.65 3.02 -0.273347914 Down 0.314002031 Zfp950 zinc finger protein 950 K09228|1|6e-31|139|mmu:414758|KRAB domain-containing zinc finger protein - - GO:0001501//skeletal system development;GO:0060537//muscle tissue development;GO:0009653//anatomical structure morphogenesis;GO:0048534//hematopoietic or lymphoid organ development;GO:0014812//muscle cell migration;GO:0008152//metabolic process;GO:0040007//growth;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001501//skeletal system development;GO:0060537//muscle tissue development;GO:0009653//anatomical structure morphogenesis;GO:0048534//hematopoietic or lymphoid organ development;GO:0014812//muscle cell migration;GO:0008152//metabolic process;GO:0040007//growth;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|149029120|gb|EDL84405.1|/1.74547e-31/rCG47099 [Rattus norvegicus] 99470 6639.43 3.743333333 3.11 -0.267408942 Down 0.314002031 Magi3 "membrane associated guanylate kinase, WW and PDZ domain containing 3" K06112|1|0.0|2110|mmu:99470|membrane-associated guanylate kinase-related GO:0043296//apical junction complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0032550;GO:0001664//G-protein coupled receptor binding;GO:0032550;GO:0001664//G-protein coupled receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0043406//positive regulation of MAP kinase activity;GO:0012501//programmed cell death;GO:0043406//positive regulation of MAP kinase activity "gi|148675629|gb|EDL07576.1|/0/membrane associated guanylate kinase, WW and PDZ domain containing 3, isoform CRA_c, partial [Mus musculus]" 208768 3203 3.893333333 4.613333333 0.244803669 Up 0.314002031 Sde2 SDE2 telomere maintenance homolog (S. pombe) K12827|1|2e-08|64.3|obi:106868824|splicing factor 3A subunit 3 - - - gi|22122373|ref|NP_666055.1|/0/protein SDE2 homolog [Mus musculus] 18670 4083 9.886666667 8.746666667 -0.176750878 Down 0.313992629 Abcb4 "ATP-binding cassette, sub-family B (MDR/TAP), member 4" "K05659|1|0.0|2312|mmu:18670|ATP-binding cassette, subfamily B (MDR/TAP), member 4 [EC:3.6.3.44]" - - - gi|161086924|ref|NP_032856.2|/0/phosphatidylcholine translocator ABCB4 [Mus musculus] 12328 1387 8.75 9.893333333 0.177173669 Up 0.313992629 Caml calcium modulating ligand - GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0005515//protein binding GO:0006950//response to stress;GO:0023051//regulation of signaling;GO:0038127//ERBB signaling pathway gi|78126155|ref|NP_031622.2|/4.21545e-156/calcium signal-modulating cyclophilin ligand [Mus musculus] 229658 4214 3.53 2.916666667 -0.275347667 Down 0.313983226 Vangl1 "vang-like 1 (van gogh, Drosophila)" K04510|1|0.0|882|mmu:229658|vang-like GO:0031224//intrinsic component of membrane - GO:0032502//developmental process gi|260099697|ref|NP_808213.2|/0/vang-like protein 1 [Mus musculus] 218294 5649.42 2.746666667 2.203333333 -0.317994066 Down 0.313973824 Cdc14b CDC14 cell division cycle 14B K06639|1|0.0|962|mmu:218294|cell division cycle 14 [EC:3.1.3.16 3.1.3.48] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity GO:0006470//protein dephosphorylation;GO:0006259//DNA metabolic process;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0000077//DNA damage checkpoint;GO:0006470//protein dephosphorylation;GO:0006259//DNA metabolic process;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0000077//DNA damage checkpoint gi|172072673|ref|NP_001116461.1|/0/dual specificity protein phosphatase CDC14B isoform 2 [Mus musculus] 13448 1809 2.156666667 2.693333333 0.320589581 Up 0.313973824 Dok1 docking protein 1 K14752|1|0.0|859|mmu:13448|docking protein 1 GO:0044424;GO:0044424 GO:0004871//signal transducer activity;GO:0008289//lipid binding;GO:0005102//receptor binding;GO:0004871//signal transducer activity;GO:0008289//lipid binding;GO:0005102//receptor binding GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007264//small GTPase mediated signal transduction gi|171916083|ref|NP_034200.4|/0/docking protein 1 isoform 1 [Mus musculus] 13347 2091.93 19.19666667 17.34 -0.146751923 Down 0.313955019 Dffa "DNA fragmentation factor, alpha subunit" "K02310|1|4e-134|479|mmu:13347|DNA fragmentation factor, 45 kD, alpha subunit" GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin - "GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0000737//DNA catabolic process, endonucleolytic;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process;GO:0000737//DNA catabolic process, endonucleolytic" "gi|148682901|gb|EDL14848.1|/1.82125e-145/DNA fragmentation factor, alpha subunit, isoform CRA_c, partial [Mus musculus]" 19679 6951.37 26.61666667 24.14 -0.140904231 Down 0.313945617 Pitpnm2 "phosphatidylinositol transfer protein, membrane-associated 2" K00469|1|3e-11|75.1|pss:102444630|inositol oxygenase [EC:1.13.99.1];K13619|2|2e-07|62.4|ame:724115|phospholipase DDHD1 [EC:3.1.1.-] - - - - 67126 419 477.3566667 519.68 0.12255593 Up 0.313917409 Atp5e "ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit" K02135|1|2e-14|79.3|cge:103162776|F-type H+-transporting ATPase subunit epsilon "GO:0033178//proton-transporting two-sector ATPase complex, catalytic domain;GO:0005753//mitochondrial proton-transporting ATP synthase complex" GO:0019829//cation-transporting ATPase activity GO:0006818//hydrogen transport;GO:0022900//electron transport chain;GO:0006754//ATP biosynthetic process;GO:0009154//purine ribonucleotide catabolic process;GO:0006839//mitochondrial transport "gi|589957638|ref|XP_006991418.1|/3.52989e-16/PREDICTED: ATP synthase subunit epsilon, mitochondrial-like [Peromyscus maniculatus bairdii]" 72123 4155 3.293333333 2.7 -0.286589134 Down 0.313823386 Ccdc71l coiled-coil domain containing 71 like "K06243|1|2e-06|58.5|tgu:100222711|laminin, beta 2" - - - "gi|148704945|gb|EDL36892.1|/1.93699e-84/mCG142431, partial [Mus musculus]" 69297 1338 0.043333333 0.256666667 2.566346823 Up 0.313766971 Lrrc46 leucine rich repeat containing 46 K19753|1|2e-12|75.9|aqu:100634723|protein TilB - - - gi|31982634|ref|NP_081302.2|/5.13985e-119/leucine-rich repeat-containing protein 46 [Mus musculus] 20300 1084.98 0.783333333 1.163333333 0.57056628 Up 0.313691752 Ccl25 chemokine (C-C motif) ligand 25 K13072|1|8e-82|306|mmu:20300|C-C motif chemokine 25 GO:0044421;GO:0044421 GO:0048020//CCR chemokine receptor binding;GO:0005125//cytokine activity;GO:0048020//CCR chemokine receptor binding;GO:0005125//cytokine activity GO:0006952//defense response;GO:0002376//immune system process;GO:0042221//response to chemical;GO:0006952//defense response;GO:0002376//immune system process;GO:0042221//response to chemical gi|755524413|ref|XP_011240345.1|/1.19134e-101/PREDICTED: C-C motif chemokine 25 isoform X1 [Mus musculus] 108909 3293 11.57666667 10.30333333 -0.168108757 Down 0.313663545 Aida "axin interactor, dorsalization associated" - GO:0005737//cytoplasm GO:0005515//protein binding GO:0007254//JNK cascade;GO:0016055//Wnt signaling pathway;GO:0043393//regulation of protein binding;GO:0009953//dorsal/ventral pattern formation;GO:0043407//negative regulation of MAP kinase activity;GO:0051093//negative regulation of developmental process "gi|32189430|ref|NP_859421.1|/2.76736e-147/axin interactor, dorsalization-associated protein [Mus musculus]" 18619 1442 4.423333333 5.18 0.227818133 Up 0.313578924 Penk preproenkephalin K18832|1|1e-158|561|mmu:18619|proenkephalin A - GO:0005102//receptor binding GO:0007600//sensory perception;GO:0007186//G-protein coupled receptor signaling pathway;GO:0002209//behavioral defense response gi|50950119|ref|NP_001002927.1|/1.06387e-157/proenkephalin-A precursor [Mus musculus] 21858 3635 45.06 49.25333333 0.128374052 Up 0.313541314 Timp2 tissue inhibitor of metalloproteinase 2 K16866|1|2e-49|201|lcm:102358642|metalloproteinase inhibitor 3 - - - - 14645 2822 414.75 449.3366667 0.115554812 Up 0.313541314 Glul glutamate-ammonia ligase (glutamine synthetase) K01915|1|0.0|788|mmu:14645|glutamine synthetase [EC:6.3.1.2] GO:0032991//macromolecular complex;GO:0043025//neuronal cell body;GO:0033267;GO:0005783//endoplasmic reticulum GO:0046914//transition metal ion binding;GO:0045502//dynein binding;GO:0032550;GO:0016597//amino acid binding;GO:0016211;GO:0016831//carboxy-lyase activity "GO:0006541//glutamine metabolic process;GO:0050796//regulation of insulin secretion;GO:0035249//synaptic transmission, glutamatergic;GO:0008284//positive regulation of cell proliferation;GO:0051259//protein oligomerization;GO:0009746;GO:0001505//regulation of neurotransmitter levels;GO:0006536//glutamate metabolic process" gi|31982332|ref|NP_032157.2|/0/glutamine synthetase [Mus musculus] 12373 2544 399.67 433.8566667 0.118409213 Up 0.313541314 Casq2 calsequestrin 2 K01539|1|7e-114|414|fch:102059303|sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9];K09580|3|5e-10|69.3|lgi:LOTGIDRAFT_184255|protein disulfide-isomerase A1 [EC:5.3.4.1];K17264|5|3e-09|67.0|mdo:100011005|endoplasmic reticulum resident protein 44 - - - - 545938 3511 1.44 1.903333333 0.402459433 Up 0.313531912 Zfp607 zinc finger protein 607A K09228|1|0.0|1462|mmu:545938|KRAB domain-containing zinc finger protein GO:0005622//intracellular GO:0046872//metal ion binding - gi|110625613|ref|NP_001019897.2|/0/zinc finger proten 607 [Mus musculus] 252838 2852 0.22 0.486666667 1.14543044 Up 0.313531912 Tox thymocyte selection-associated high mobility group box K18808|1|2e-32|143|bfo:BRAFLDRAFT_68489|toll-like receptor 13 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding - gi|215422329|ref|NP_663757.3|/0/thymocyte selection-associated high mobility group box protein TOX [Mus musculus] 112422 2576 1.116666667 0.743333333 -0.587117385 Down 0.313522509 2610305D13Rik zinc finger protein 979 K09228|1|0.0|759|mmu:667666|KRAB domain-containing zinc finger protein - - - - 56543 7182 0.74 1.113333333 0.589288426 Up 0.313522509 Kcnd3 "potassium voltage-gated channel, Shal-related family, member 3" K04893|1|0.0|1160|mmu:56543|potassium voltage-gated channel Shal-related subfamily D member 3 - - - gi|9910302|ref|NP_064315.1|/0/potassium voltage-gated channel subfamily D member 3 isoform 2 precursor [Mus musculus] 231805 2588 3.586666667 4.263333333 0.249338186 Up 0.313353266 Pilra paired immunoglobin-like type 2 receptor alpha K15411|1|9e-148|526|mmu:231805|paired immunoglobulin-like type 2 receptor alpha GO:0031224//intrinsic component of membrane GO:0042287//MHC protein binding GO:0002762//negative regulation of myeloid leukocyte differentiation gi|23943820|ref|NP_705730.1|/7.96415e-147/paired immunoglobulin-like type 2 receptor alpha precursor [Mus musculus] 116972 930 3.053333333 2.483333333 -0.298107173 Down 0.313325059 Fam57a "family with sequence similarity 57, member A" - GO:0031224//intrinsic component of membrane - - gi|110625847|ref|NP_082049.1|/1.48925e-147/protein FAM57A [Mus musculus] 71898 1509 0.66 1.023333333 0.632738225 Up 0.313315657 Apol9b apolipoprotein L 9b K14480|1|1e-146|522|mmu:71898|apolipoprotein L - - - "gi|148697701|gb|EDL29648.1|/8.11149e-172/RIKEN cDNA 2310016F22, isoform CRA_c, partial [Mus musculus]" 73516 1173 0.473333333 0.806666667 0.769116118 Up 0.313268645 1700086O06Rik RIKEN cDNA 1700086O06 gene - - - - - 64930 7713.98 5.793333333 4.99 -0.215353861 Down 0.313193426 Tsc1 tuberous sclerosis 1 K07206|1|0.0|1943|mmu:64930|tuberous sclerosis 1 GO:0043005//neuron projection;GO:0031252//cell leading edge;GO:0043234//protein complex;GO:0015629//actin cytoskeleton;GO:0043227//membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043005//neuron projection;GO:0031252//cell leading edge;GO:0043234//protein complex;GO:0015629//actin cytoskeleton;GO:0043227//membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043005//neuron projection;GO:0031252//cell leading edge;GO:0043234//protein complex;GO:0015629//actin cytoskeleton;GO:0043227//membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0060589;GO:0005515//protein binding;GO:0060589;GO:0005515//protein binding;GO:0060589;GO:0005515//protein binding GO:0014020;GO:0001932//regulation of protein phosphorylation;GO:0043434//response to peptide hormone;GO:0032231//regulation of actin filament bundle assembly;GO:0042254//ribosome biogenesis;GO:0021543//pallium development;GO:0030001//metal ion transport;GO:0035051//cardiocyte differentiation;GO:0008366//axon ensheathment;GO:0008361//regulation of cell size;GO:0009968//negative regulation of signal transduction;GO:0008283//cell proliferation;GO:0051259//protein oligomerization;GO:0006412//translation;GO:0010921//regulation of phosphatase activity;GO:0031647//regulation of protein stability;GO:0001954//positive regulation of cell-matrix adhesion;GO:0014020;GO:0001932//regulation of protein phosphorylation;GO:0043434//response to peptide hormone;GO:0032231//regulation of actin filament bundle assembly;GO:0042254//ribosome biogenesis;GO:0021543//pallium development;GO:0030001//metal ion transport;GO:0035051//cardiocyte differentiation;GO:0008366//axon ensheathment;GO:0008361//regulation of cell size;GO:0009968//negative regulation of signal transduction;GO:0008283//cell proliferation;GO:0051259//protein oligomerization;GO:0006412//translation;GO:0010921//regulation of phosphatase activity;GO:0031647//regulation of protein stability;GO:0001954//positive regulation of cell-matrix adhesion;GO:0014020;GO:0001932//regulation of protein phosphorylation;GO:0043434//response to peptide hormone;GO:0032231//regulation of actin filament bundle assembly;GO:0042254//ribosome biogenesis;GO:0021543//pallium development;GO:0030001//metal ion transport;GO:0035051//cardiocyte differentiation;GO:0008366//axon ensheathment;GO:0008361//regulation of cell size;GO:0009968//negative regulation of signal transduction;GO:0008283//cell proliferation;GO:0051259//protein oligomerization;GO:0006412//translation;GO:0010921//regulation of phosphatase activity;GO:0031647//regulation of protein stability;GO:0001954//positive regulation of cell-matrix adhesion gi|79750409|ref|NP_075025.2|/0/hamartin isoform 2 [Mus musculus] 16181 2424.06 0.893333333 1.286666667 0.526367847 Up 0.313146414 Il1rn interleukin 1 receptor antagonist K05481|1|3e-87|325|mmu:16181|interleukin 1 receptor antagonist GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0044421;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0044421;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0044421 GO:0005149//interleukin-1 receptor binding;GO:0005152//interleukin-1 receptor antagonist activity;GO:0005149//interleukin-1 receptor binding;GO:0005152//interleukin-1 receptor antagonist activity;GO:0005149//interleukin-1 receptor binding;GO:0005152//interleukin-1 receptor antagonist activity GO:0043436;GO:0006915//apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0030072//peptide hormone secretion;GO:0042391//regulation of membrane potential;GO:0031960//response to corticosteroid;GO:0010469//regulation of receptor activity;GO:0007611//learning or memory;GO:0002437//inflammatory response to antigenic stimulus;GO:0016477//cell migration;GO:0014047//glutamate secretion;GO:0002526//acute inflammatory response;GO:0002237//response to molecule of bacterial origin;GO:0044703;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0022408//negative regulation of cell-cell adhesion;GO:0043436;GO:0006915//apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0030072//peptide hormone secretion;GO:0042391//regulation of membrane potential;GO:0031960//response to corticosteroid;GO:0010469//regulation of receptor activity;GO:0007611//learning or memory;GO:0002437//inflammatory response to antigenic stimulus;GO:0016477//cell migration;GO:0014047//glutamate secretion;GO:0002526//acute inflammatory response;GO:0002237//response to molecule of bacterial origin;GO:0044703;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0022408//negative regulation of cell-cell adhesion;GO:0043436;GO:0006915//apoptotic process;GO:0043406//positive regulation of MAP kinase activity;GO:0030072//peptide hormone secretion;GO:0042391//regulation of membrane potential;GO:0031960//response to corticosteroid;GO:0010469//regulation of receptor activity;GO:0007611//learning or memory;GO:0002437//inflammatory response to antigenic stimulus;GO:0016477//cell migration;GO:0014047//glutamate secretion;GO:0002526//acute inflammatory response;GO:0002237//response to molecule of bacterial origin;GO:0044703;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0022408//negative regulation of cell-cell adhesion gi|13624317|ref|NP_112444.1|/1.03092e-87/interleukin-1 receptor antagonist protein isoform 1 [Mus musculus] 72720 3682 0.373333333 0.686666667 0.879145605 Up 0.313127609 Zfp248 zinc finger protein 248 K09228|1|0.0|1234|mmu:72720|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - "gi|148667181|gb|EDK99597.1|/0/zinc finger protein 248, isoform CRA_b, partial [Mus musculus]" 105242657 1567 0.036666667 0.24 2.710493383 Up 0.31309 Hoxaas2 Hoxa cluster antisense RNA 2 - - - - - 72630 2945 26.92333333 24.50666667 -0.135682773 Down 0.313071195 Hspa12b heat shock protein 12B - - GO:0032550 - gi|21312236|ref|NP_082582.1|/0/heat shock 70 kDa protein 12B [Mus musculus] 14004 910 306.3233333 333.7366667 0.123654935 Up 0.313005378 Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 K11837|1|5e-21|103|bfo:BRAFLDRAFT_121867|ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle - - "gi|148687546|gb|EDL19493.1|/2.59101e-48/mCG145321, isoform CRA_a, partial [Mus musculus]" 12895 2894 346.06 319.31 -0.116064459 Down 0.312901952 Cpt1b "carnitine palmitoyltransferase 1b, muscle" "K19523|1|0.0|1589|mmu:12895|carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]" GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane GO:0005488//binding;GO:0016406//carnitine O-acyltransferase activity GO:0015908//fatty acid transport;GO:0009062//fatty acid catabolic process "gi|162287165|ref|NP_034078.2|/0/carnitine O-palmitoyltransferase 1, muscle isoform [Mus musculus]" 18844 9045 6.48 5.616666667 -0.206279628 Down 0.312901952 Plxna1 plexin A1 K06820|1|0.0|3654|rno:362398|plexin A GO:0031224//intrinsic component of membrane;GO:0044464 GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity GO:0060445//branching involved in salivary gland morphogenesis;GO:0007154//cell communication gi|148666850|gb|EDK99266.1|/0/plexin A1 [Mus musculus] 100206 1368 5.57 6.433333333 0.207889114 Up 0.312901952 Adprhl2 ADP-ribosylhydrolase like 2 K11687|1|2e-178|627|mmu:100206|poly(ADP-ribose) glycohydrolase ARH3 [EC:3.2.1.143] GO:0044429;GO:0031981//nuclear lumen "GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0043169//cation binding" - "gi|148698345|gb|EDL30292.1|/2.05678e-179/ADP-ribosylhydrolase like 2, isoform CRA_c, partial [Mus musculus]" 116891 3705.79 5.626666667 6.49 0.20593798 Up 0.312901952 Derl2 "Der1-like domain family, member 2" K13989|1|2e-107|377|cge:100755526|Derlin-2/3 GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0005768//endosome;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0005768//endosome;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0005768//endosome;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0005768//endosome GO:0005488//binding;GO:0005488//binding GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016049//cell growth;GO:0006886//intracellular protein transport;GO:0008283//cell proliferation;GO:0035966//response to topologically incorrect protein;GO:0006984//ER-nucleus signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016049//cell growth;GO:0006886//intracellular protein transport;GO:0008283//cell proliferation;GO:0035966//response to topologically incorrect protein;GO:0006984//ER-nucleus signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016049//cell growth;GO:0006886//intracellular protein transport;GO:0008283//cell proliferation;GO:0035966//response to topologically incorrect protein;GO:0006984//ER-nucleus signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016049//cell growth;GO:0006886//intracellular protein transport;GO:0008283//cell proliferation;GO:0035966//response to topologically incorrect protein;GO:0006984//ER-nucleus signaling pathway "gi|148680691|gb|EDL12638.1|/5.62627e-115/Der1-like domain family, member 2, isoform CRA_b, partial [Mus musculus]" 75641 420 0.753333333 0.43 -0.808951707 Down 0.31285494 1700029I15Rik RIKEN cDNA 1700029I15 gene - - - - "gi|148695652|gb|EDL27599.1|/2.75825e-61/RIKEN cDNA 1700029I15, partial [Mus musculus]" 23877 2629.78 13.00666667 14.49666667 0.156469931 Up 0.31285494 Fiz1 Flt3 interacting zinc finger protein 1 K09228|1|2e-42|177|lcm:106705198|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0019900//kinase binding;GO:0046872//metal ion binding;GO:0019900//kinase binding;GO:0046872//metal ion binding;GO:0019900//kinase binding;GO:0046872//metal ion binding;GO:0019900//kinase binding;GO:0046872//metal ion binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148699330|gb|EDL31277.1|/0/Flt3 interacting zinc finger protein 1, isoform CRA_b, partial [Mus musculus]" 22441 1251.1 0.74 0.423333333 -0.80573118 Down 0.31285494 Xlr X-linked lymphocyte-regulated K19528|1|4e-29|132|ngi:103733733|synaptonemal complex protein 3 - - - gi|6756021|ref|NP_035855.1|/2.48699e-112/X-linked lymphocyte-regulated protein PM1 isoform a [Mus musculus] 78038 2146 41.84666667 45.91 0.133695724 Up 0.312845538 Mccc2 methylcrotonoyl-Coenzyme A carboxylase 2 (beta) K01969|1|0.0|1063|mmu:78038|3-methylcrotonyl-CoA carboxylase beta subunit [EC:6.4.1.4] GO:0044429 GO:0032550;GO:0016421//CoA carboxylase activity GO:0006551//leucine metabolic process;GO:0006732 "gi|73622267|ref|NP_084302.1|/0/methylcrotonoyl-CoA carboxylase beta chain, mitochondrial [Mus musculus]" 14670 2744 25.33 22.91666667 -0.144449864 Down 0.312845538 Gnl1 guanine nucleotide binding protein-like 1 K14539|1|1e-41|174|asn:102370655|large subunit GTPase 1 [EC:3.6.1.-] - - - gi|122937361|ref|NP_032162.2|/0/guanine nucleotide-binding protein-like 1 [Mus musculus] 327768 1989 1.556666667 1.133333333 -0.457887804 Down 0.312770319 A330049N07Rik RIKEN cDNA A330049N07 gene - - - - - 57246 6436 7.976666667 6.97 -0.194627335 Down 0.312732709 Tbx20 T-box 20 K10185|1|5e-150|533|mmu:57246|T-box protein 20 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding GO:0021522//spinal cord motor neuron differentiation;GO:0003012//muscle system process;GO:0008284//positive regulation of cell proliferation;GO:0003176//aortic valve development;GO:0003184//pulmonary valve morphogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0001837//epithelial to mesenchymal transition;GO:0016477//cell migration;GO:0003151//outflow tract morphogenesis;GO:0002011//morphogenesis of an epithelial sheet;GO:0003209//cardiac atrium morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0003143//embryonic heart tube morphogenesis;GO:0048845//venous blood vessel morphogenesis;GO:0001525//angiogenesis;GO:0003013//circulatory system process;GO:0003002//regionalization;GO:0003208//cardiac ventricle morphogenesis;GO:0007183//SMAD protein complex assembly;GO:0021522//spinal cord motor neuron differentiation;GO:0003012//muscle system process;GO:0008284//positive regulation of cell proliferation;GO:0003176//aortic valve development;GO:0003184//pulmonary valve morphogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0001707//mesoderm formation;GO:0001837//epithelial to mesenchymal transition;GO:0016477//cell migration;GO:0003151//outflow tract morphogenesis;GO:0002011//morphogenesis of an epithelial sheet;GO:0003209//cardiac atrium morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0003143//embryonic heart tube morphogenesis;GO:0048845//venous blood vessel morphogenesis;GO:0001525//angiogenesis;GO:0003013//circulatory system process;GO:0003002//regionalization;GO:0003208//cardiac ventricle morphogenesis;GO:0007183//SMAD protein complex assembly;GO:0021522//spinal cord motor neuron differentiation;GO:0003012//muscle system process;GO:0008284//positive regulation of cell proliferation;GO:0003176//aortic valve development;GO:0003184//pulmonary valve morphogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0001837//epithelial to mesenchymal transition;GO:0016477//cell migration;GO:0003151//outflow tract morphogenesis;GO:0002011//morphogenesis of an epithelial sheet;GO:0003209//cardiac atrium morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0003143//embryonic heart tube morphogenesis;GO:0048845//venous blood vessel morphogenesis;GO:0001525//angiogenesis;GO:0003013//circulatory system process;GO:0003002//regionalization;GO:0003208//cardiac ventricle morphogenesis;GO:0007183//SMAD protein complex assembly gi|326633198|ref|NP_001192014.1|/6.57913e-152/T-box transcription factor TBX20 isoform c [Mus musculus] 246707 3910 16.13333333 17.94 0.153135343 Up 0.312713904 Emilin2 elastin microfibril interfacer 2 K20478|1|6e-10|69.7|acs:100562023|golgin subfamily B member 1;K03986|2|2e-09|67.8|mgp:100546926|complement C1q subcomponent subunit A;K17751|5|2e-08|65.1|crg:105329786|myosin heavy chain 6/7 - - - - 414127 1332 0.553333333 0.273333333 -1.017487427 Down 0.312704502 G630055G22Rik RIKEN cDNA G630055G22 gene - - GO:0004518//nuclease activity - "gi|148678000|gb|EDL09947.1|/5.5886e-49/mCG145143, partial [Mus musculus]" 15412 2566 0.276666667 0.553333333 1 Up 0.312704502 Hoxb4 homeobox B4 K09304|1|2e-116|422|mmu:15412|homeobox protein HoxA/B/C/D4 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0001501//skeletal system development;GO:0030097//hemopoiesis;GO:0017145//stem cell division;GO:0006366//transcription from RNA polymerase II promoter;GO:0045597//positive regulation of cell differentiation;GO:0048562//embryonic organ morphogenesis;GO:0003002//regionalization;GO:0002009//morphogenesis of an epithelium gi|110625619|ref|NP_034589.3|/1.60145e-115/homeobox protein Hox-B4 [Mus musculus] 17127 5090 3.98 4.693333333 0.237844497 Up 0.312695099 Smad3 SMAD family member 3 K04500|1|0.0|846|rro:104662580|mothers against decapentaplegic homolog 2/3 GO:0019866//organelle inner membrane;GO:0005667//transcription factor complex;GO:0044444//cytoplasmic part "GO:0046332//SMAD binding;GO:0005160//transforming growth factor beta receptor binding;GO:0019900//kinase binding;GO:0043566//structure-specific DNA binding;GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0032182//ubiquitin-like protein binding;GO:0005072//transforming growth factor beta receptor, cytoplasmic mediator activity;GO:0003682//chromatin binding" GO:0032906;GO:0035411//catenin import into nucleus;GO:0032907//transforming growth factor beta3 production;GO:0001837//epithelial to mesenchymal transition;GO:0002088//lens development in camera-type eye;GO:0000578//embryonic axis specification;GO:0009952//anterior/posterior pattern specification;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0032611//interleukin-1 beta production;GO:0003143//embryonic heart tube morphogenesis;GO:0007440//foregut morphogenesis;GO:0001704//formation of primary germ layer;GO:0032924//activin receptor signaling pathway;GO:0032102;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0030282//bone mineralization;GO:0030072//peptide hormone secretion;GO:0006954//inflammatory response;GO:0036314;GO:0009895;GO:0022402//cell cycle process;GO:0008637//apoptotic mitochondrial changes;GO:0001954//positive regulation of cell-matrix adhesion;GO:0008285//negative regulation of cell proliferation;GO:0032233//positive regulation of actin filament bundle assembly;GO:0014706//striated muscle tissue development;GO:0002682//regulation of immune system process;GO:0000278//mitotic cell cycle;GO:0002062//chondrocyte differentiation;GO:0001649//osteoblast differentiation;GO:0035270//endocrine system development;GO:0010628//positive regulation of gene expression;GO:0048704//embryonic skeletal system morphogenesis;GO:0048332//mesoderm morphogenesis;GO:0030509//BMP signaling pathway;GO:0016477//cell migration;GO:0009746;GO:0001932//regulation of protein phosphorylation;GO:0030323//respiratory tube development;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0031647//regulation of protein stability;GO:0030177//positive regulation of Wnt signaling pathway;GO:0016049//cell growth;GO:0046649//lymphocyte activation;GO:0034330;GO:0019048//modulation by virus of host morphology or physiology;GO:0050918//positive chemotaxis;GO:0012502//induction of programmed cell death;GO:0010692;GO:0042307//positive regulation of protein import into nucleus gi|724826190|ref|XP_010361911.1|/0/PREDICTED: mothers against decapentaplegic homolog 3 isoform X1 [Rhinopithecus roxellana] 19193 1774 0.303333333 0.076666667 -1.984232684 Down 0.31265749 Pipox pipecolic acid oxidase K00306|1|0.0|810|mmu:19193|sarcosine oxidase / L-pipecolate oxidase [EC:1.5.3.1 1.5.3.7] - - - - 50926 2761 22.66 25.05333333 0.144854705 Up 0.312601076 Hnrnpdl heterogeneous nuclear ribonucleoprotein D-like K13044|1|3e-156|555|mmu:50926|heterogeneous nuclear ribonucleoprotein A/B/D GO:0043231//intracellular membrane-bounded organelle GO:0003729//mRNA binding;GO:0070717//poly-purine tract binding;GO:0043566//structure-specific DNA binding GO:0016070//RNA metabolic process;GO:0010467//gene expression gi|148664250|ref|NP_057899.2|/2.2524e-155/heterogeneous nuclear ribonucleoprotein D-like [Mus musculus] 93843 1506 4.27 5.023333333 0.234408941 Up 0.312488247 Pnck pregnancy upregulated non-ubiquitously expressed CaM kinase K08795|1|0.0|692|mmu:93843|pregnancy upregulated non-ubiquitously expressed CaM kinase [EC:2.7.11.17] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process "gi|148697942|gb|EDL29889.1|/0/pregnancy upregulated non-ubiquitously expressed CaM kinase, isoform CRA_a, partial [Mus musculus]" 225913 2350 4.266666667 5.013333333 0.232660757 Up 0.312488247 Tkfc "triokinase, FMN cyclase" K00863|1|0.0|962|mmu:225913|triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing) [EC:2.7.1.28 2.7.1.29 4.6.1.15] - GO:0043169//cation binding;GO:0009975//cyclase activity;GO:0016301//kinase activity;GO:0032550 GO:0019400;GO:0006796//phosphate-containing compound metabolic process gi|569006946|ref|XP_006527004.1|/0/PREDICTED: bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing) isoform X2 [Mus musculus] 67526 2492 10.21333333 11.46666667 0.166992268 Up 0.312450637 Atg12 autophagy related 12 K08336|1|1e-62|243|mmu:67526|ubiquitin-like protein ATG12 GO:0000407//pre-autophagosomal structure;GO:0032991//macromolecular complex GO:0005488//binding GO:0001818//negative regulation of cytokine production;GO:0006952//defense response;GO:0044248;GO:0007033//vacuole organization gi|145966752|ref|NP_080493.2|/1.28606e-61/ubiquitin-like protein ATG12 [Mus musculus] 234086 1579 3.28 3.923333333 0.2583841 Up 0.312441235 Erich1 glutamate rich 1 - - - - "gi|148690237|gb|EDL22184.1|/1.08604e-158/mCG18955, isoform CRA_b, partial [Mus musculus]" 66431 810 26.47666667 24.09666667 -0.135887913 Down 0.312431833 Oxld1 oxidoreductase like domain containing 1 - GO:0043231//intracellular membrane-bounded organelle - - gi|13384992|ref|NP_079836.1|/2.59566e-107/oxidoreductase-like domain-containing protein 1 [Mus musculus] 230088 3133.99 22.49 24.86 0.144542635 Up 0.31226259 Fam214b "family with sequence similarity 214, member B" - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|74203951|dbj|BAE28988.1|/0/unnamed protein product [Mus musculus] 56486 1122 235.86 256.9866667 0.12376274 Up 0.312196773 Gabarap gamma-aminobutyric acid receptor associated protein K08341|1|3e-64|248|ngi:103752156|GABA(A) receptor-associated protein GO:0015630//microtubule cytoskeleton;GO:0000323//lytic vacuole;GO:0005774//vacuolar membrane;GO:0031982//vesicle;GO:0012505//endomembrane system;GO:0005783//endoplasmic reticulum GO:0005102//receptor binding;GO:0015631//tubulin binding GO:0012501//programmed cell death;GO:0044248;GO:0007267//cell-cell signaling;GO:0007010//cytoskeleton organization;GO:0006886//intracellular protein transport "gi|149053135|gb|EDM04952.1|/1.70195e-103/gamma-aminobutyric acid receptor associated protein, isoform CRA_b [Rattus norvegicus]" 67145 1988.38 16.48666667 18.27666667 0.148703234 Up 0.312159164 Tomm34 translocase of outer mitochondrial membrane 34 K17766|1|2e-133|479|mmu:67145|mitochondrial import receptor subunit TOM34 GO:0031966//mitochondrial membrane;GO:0031966//mitochondrial membrane GO:0005515//protein binding;GO:0005515//protein binding GO:0006605//protein targeting;GO:0006605//protein targeting gi|599044572|ref|NP_001278084.1|/1.43009e-134/mitochondrial import receptor subunit TOM34 isoform a [Mus musculus] 223455 6236 17.66333333 15.87 -0.154455498 Down 0.312159164 6-Mar membrane-associated ring finger (C3HC4) 6 K10661|1|0.0|1566|mmu:223455|E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27] GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0046914//transition metal ion binding;GO:0044390//ubiquitin-like protein conjugating enzyme binding;GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination gi|71043942|ref|NP_766194.2|/0/E3 ubiquitin-protein ligase MARCH6 [Mus musculus] 74251 2558 23.60333333 25.95333333 0.136929228 Up 0.312036933 Ankrd9 ankyrin repeat domain 9 - - GO:0003824//catalytic activity - "gi|148686700|gb|EDL18647.1|/1.62215e-176/ankyrin repeat domain 9, isoform CRA_a, partial [Mus musculus]" 277978 2497 2.13 2.663333333 0.322379572 Up 0.311999323 Exoc3l exocyst complex component 3-like K19987|1|0.0|1243|mmu:277978|exocyst complex component 3-like protein "GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0005488//binding GO:0002790//peptide secretion;GO:0016192//vesicle-mediated transport gi|29244320|ref|NP_808456.1|/0/exocyst complex component 3-like protein [Mus musculus] 68944 4474 10.10666667 11.34333333 0.166537398 Up 0.311971116 Tmco1 transmembrane and coiled-coil domains 1 K02920|1|8e-07|53.9|tup:102501669|large subunit ribosomal protein L36e GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|817307535|ref|XP_012324330.1|/8.21901e-89/PREDICTED: transmembrane and coiled-coil domain-containing protein 1 isoform X2 [Aotus nancymaae] 26427 2284 6.2 7.123333333 0.200284287 Up 0.311924104 Creb3l1 cAMP responsive element binding protein 3-like 1 K09048|1|0.0|895|mmu:26427|cyclic AMP-responsive element-binding protein 3 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0003677//DNA binding" "GO:0030278//regulation of ossification;GO:0006351//transcription, DNA-templated;GO:0035966//response to topologically incorrect protein" gi|117606377|ref|NP_036087.2|/0/cyclic AMP-responsive element-binding protein 3-like protein 1 [Mus musculus] 78500 709 1.806666667 1.36 -0.409723699 Down 0.311924104 1700063D05Rik RIKEN cDNA 1700063D05 gene - - - - - 228576 1967 7.166666667 6.243333333 -0.19898576 Down 0.311924104 Mall "mal, T cell differentiation protein-like" - GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0030135//coated vesicle - - gi|21704048|ref|NP_663507.1|/1.52783e-83/MAL-like protein [Mus musculus] 81535 3324 8.153333333 9.266666667 0.184660479 Up 0.311839482 Sgpp1 sphingosine-1-phosphate phosphatase 1 K04716|1|0.0|771|mmu:81535|sphingosine-1-phosphate phosphatase 1 [EC:3.1.3.-] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0031090//organelle membrane GO:0016791//phosphatase activity GO:0012501//programmed cell death;GO:0006644//phospholipid metabolic process;GO:0006066//alcohol metabolic process;GO:0006665//sphingolipid metabolic process gi|13507712|ref|NP_109675.1|/0/sphingosine-1-phosphate phosphatase 1 [Mus musculus] 269854 1612 2.65 3.233333333 0.287029887 Up 0.311839482 Nat14 N-acetyltransferase 14 - - - - "gi|148699324|gb|EDL31271.1|/3.95984e-63/cDNA sequence BC047219, isoform CRA_b, partial [Mus musculus]" 216156 2954 16.62333333 18.39666667 0.146234683 Up 0.311679642 Wdr18 WD repeat domain 18 K14829|1|0.0|845|mmu:216156|pre-rRNA-processing protein IPI3 GO:0031981//nuclear lumen - GO:0032502//developmental process gi|83649741|ref|NP_780659.2|/0/WD repeat-containing protein 18 [Mus musculus] 109979 1362.49 233.3466667 215.4333333 -0.115233368 Down 0.311510399 Art3 ADP-ribosyltransferase 3 K00775|1|0.0|654|mmu:109979|ADP-ribosyltransferase 3 [EC:2.4.2.31] - - - - 319713 4320.71 44.15666667 40.31666667 -0.131254905 Down 0.311482192 Ablim3 "actin binding LIM protein family, member 3" K07520|1|0.0|1335|mmu:319713|actin-binding LIM protein GO:0044424;GO:0044424 GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding GO:0006996//organelle organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006996//organelle organization;GO:0006366//transcription from RNA polymerase II promoter gi|50510665|dbj|BAD32318.1|/0/mKIAA0843 protein [Mus musculus] 12868 545 199.4133333 217.09 0.122531396 Up 0.311472789 Cox8a cytochrome c oxidase subunit VIIIa K02273|1|2e-32|140|mmu:12868|cytochrome c oxidase subunit 8 GO:0031224//intrinsic component of membrane;GO:0005746//mitochondrial respiratory chain GO:0015002//heme-copper terminal oxidase activity GO:0044710 "gi|148700340|gb|EDL32287.1|/1.05087e-43/mCG51330, partial [Mus musculus]" 78581 2917 3.876666667 4.573333333 0.238429385 Up 0.311453985 Utp23 UTP23 small subunit processome component K14773|1|9e-126|454|mmu:78581|U3 small nucleolar RNA-associated protein 23 GO:0043231//intracellular membrane-bounded organelle - GO:0042254//ribosome biogenesis gi|21313442|ref|NP_084408.1|/7.54556e-125/rRNA-processing protein UTP23 homolog [Mus musculus] 22335 1422.66 203.7266667 221.3066667 0.119412078 Up 0.311444582 Vdac3 voltage-dependent anion channel 3 K15041|1|7e-165|582|mmu:22335|voltage-dependent anion channel protein 3 GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane;GO:0019866//organelle inner membrane;GO:0005783//endoplasmic reticulum;GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane;GO:0019866//organelle inner membrane;GO:0005783//endoplasmic reticulum GO:0022829//wide pore channel activity;GO:0005244//voltage-gated ion channel activity;GO:0036094//small molecule binding;GO:0022829//wide pore channel activity;GO:0005244//voltage-gated ion channel activity GO:0007611//learning or memory;GO:0006820//anion transport;GO:0006863//purine nucleobase transport;GO:0007268//chemical synaptic transmission;GO:0002209//behavioral defense response;GO:0007611//learning or memory;GO:0006820//anion transport;GO:0007268//chemical synaptic transmission;GO:0002209//behavioral defense response gi|312222784|ref|NP_001185927.1|/1.50513e-164/voltage-dependent anion-selective channel protein 3 isoform 1 [Mus musculus] 20657 2045 40.69333333 44.52333333 0.129769146 Up 0.31143518 Sod3 "superoxide dismutase 3, extracellular" "K16627|1|3e-126|454|mmu:20657|superoxide dismutase, Cu-Zn family [EC:1.15.1.1]" - - - gi|6755600|ref|NP_035565.1|/2.89368e-125/extracellular superoxide dismutase [Cu-Zn] precursor [Mus musculus] 67628 1382 41.88333333 45.70666667 0.126028343 Up 0.31139757 Anp32b "acidic (leucine-rich) nuclear phosphoprotein 32 family, member B" K18647|1|2e-83|311|mmu:67628|acidic leucine-rich nuclear phosphoprotein 32 family member B GO:0043231//intracellular membrane-bounded organelle - GO:0008283//cell proliferation;GO:0043583//ear development;GO:0007420//brain development gi|755475900|ref|XP_011250241.1|/1.742e-85/PREDICTED: LOW QUALITY PROTEIN: acidic leucine-rich nuclear phosphoprotein 32 family member B-like [Mus musculus] 109145 1364 12.65666667 14.10666667 0.156479628 Up 0.311322351 Gins4 GINS complex subunit 4 (Sld5 homolog) K10735|1|2e-114|414|mmu:109145|GINS complex subunit 4 GO:0043231//intracellular membrane-bounded organelle - GO:0006259//DNA metabolic process gi|13195660|ref|NP_077202.1|/1.94853e-113/DNA replication complex GINS protein SLD5 [Mus musculus] 109349 2962 0.383333333 0.693333333 0.854949667 Up 0.311303547 Fam163b "family with sequence similarity 163, member B" K17559|1|9e-09|65.5|dre:570052|phostensin;K16493|2|2e-07|61.2|fch:106631715|protocadherin alpha;K19607|3|3e-06|57.0|asn:102377064|X-linked retinitis pigmentosa GTPase regulator;K11093|4|4e-06|56.6|spu:575726|U1 small nuclear ribonucleoprotein 70kDa GO:0031224//intrinsic component of membrane - - gi|30425144|ref|NP_780636.1|/7.26679e-83/protein FAM163B [Mus musculus] 70456 854 197.61 214.63 0.119195788 Up 0.311265937 Mpc2 mitochondrial pyruvate carrier 2 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0008028//monocarboxylic acid transmembrane transporter activity GO:0006839//mitochondrial transport;GO:0032787//monocarboxylic acid metabolic process;GO:0006848//pyruvate transport gi|21312594|ref|NP_081706.1|/1.75997e-64/mitochondrial pyruvate carrier 2 [Mus musculus] 70767 2501.25 9.196666667 8.096666667 -0.183782967 Down 0.311209523 Prpf3 pre-mRNA processing factor 3 K12843|1|0.0|1206|chx:102188003|U4/U6 small nuclear ribonucleoprotein PRP3 - - - - 66286 770 8.376666667 9.476666667 0.178003428 Up 0.311209523 Sec11c "SEC11 homolog C, signal peptidase complex subunit" "K13280|1|1e-108|394|ssc:100524124|signal peptidase, endoplasmic reticulum-type [EC:3.4.-.-]" GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0016485//protein processing gi|545802024|ref|XP_003121761.2|/8.02904e-108/PREDICTED: signal peptidase complex catalytic subunit SEC11C isoform X1 [Sus scrofa] 26412 4691.28 18.16333333 16.41666667 -0.145867766 Down 0.31120012 Map4k2 mitogen-activated protein kinase kinase kinase kinase 2 K04414|1|0.0|997|rno:293694|mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1] GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0030695//GTPase regulator activity;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0032550;GO:0030695//GTPase regulator activity;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0032550;GO:0030695//GTPase regulator activity;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity GO:0007254//JNK cascade;GO:0016192//vesicle-mediated transport;GO:0006952//defense response;GO:0000187//activation of MAPK activity;GO:0007254//JNK cascade;GO:0016192//vesicle-mediated transport;GO:0006952//defense response;GO:0000187//activation of MAPK activity;GO:0007254//JNK cascade;GO:0016192//vesicle-mediated transport;GO:0006952//defense response;GO:0000187//activation of MAPK activity gi|755562435|ref|XP_011246933.1|/0/PREDICTED: mitogen-activated protein kinase kinase kinase kinase 2 isoform X4 [Mus musculus] 18719 2528 15.90666667 17.65666667 0.150581466 Up 0.31120012 Pip5k1b "phosphatidylinositol-4-phosphate 5-kinase, type 1 beta" K00889|1|0.0|1051|mmu:18719|1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68] GO:0031254//cell trailing edge;GO:0044444//cytoplasmic part GO:0032550;GO:0016307//phosphatidylinositol phosphate kinase activity GO:0046488//phosphatidylinositol metabolic process;GO:0046474//glycerophospholipid biosynthetic process gi|6679329|ref|NP_032872.1|/0/phosphatidylinositol 4-phosphate 5-kinase type-1 beta [Mus musculus] 208440 8026 4.293333333 5.033333333 0.229415956 Up 0.311171913 Dip2c disco interacting protein 2 homolog C - - - - - 381077 1651 4.223333333 4.96 0.231958002 Up 0.311171913 Ccdc78 coiled-coil domain containing 78 - - - - gi|260064083|ref|NP_001159401.1|/0/coiled-coil domain-containing protein 78 [Mus musculus] 66349 1700.66 40.45 44.22666667 0.128776809 Up 0.311115499 Atp5sl ATP5S-like "K09649|1|8e-23|111|amj:102566372|thymus-specific serine protease [EC:3.4.-.-];K14816|2|1e-16|91.3|tsp:Tsp_01411|pre-60S factor REI1;K07554|3|9e-14|81.6|spu:593766|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s" GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|31560249|ref|NP_079780.2|/2.75821e-130/ATP synthase subunit s-like protein isoform 2 [Mus musculus] 105351 2010 6.19 7.096666667 0.197202135 Up 0.311087292 AW209491 expressed sequence AW209491 - - - - gi|157388985|ref|NP_598828.3|/0/UPF0415 protein C7orf25 homolog [Mus musculus] 22594 2155 16.29333333 18.03 0.146117612 Up 0.311012073 Xrcc1 X-ray repair complementing defective repair in Chinese hamster cells 1 K10803|1|0.0|1093|mmu:22594|DNA-repair protein XRCC1 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding GO:0042221//response to chemical;GO:0021543//pallium development;GO:0006281//DNA repair gi|170295844|ref|NP_033558.3|/0/DNA repair protein XRCC1 [Mus musculus] 236451 1163 1.083333333 1.496666667 0.466275727 Up 0.310993268 Phf11b PHD finger protein 11B K18494|1|4e-102|374|mmu:107303348|histone-lysine N-methyltransferase SETDB2 [EC:2.1.1.43] - - - - 116873 4930 3.846666667 3.22 -0.25654813 Down 0.310974463 Stim2 stromal interaction molecule 2 K18196|1|0.0|1236|mmu:116873|stromal interaction molecule 2 GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0005262//calcium channel activity;GO:0046872//metal ion binding GO:0006875//cellular metal ion homeostasis;GO:1901341//positive regulation of store-operated calcium channel activity gi|187950829|gb|AAI37882.1|/0/Stim2 protein [Mus musculus] 71839 1982 3.173333333 3.803333333 0.261265313 Up 0.310974463 Osgin1 oxidative stress induced growth inhibitor 1 - - GO:0005102//receptor binding GO:0016049//cell growth gi|30794398|ref|NP_082226.1|/0/oxidative stress-induced growth inhibitor 1 [Mus musculus] 69714 1153.09 12.59333333 14.03666667 0.156540174 Up 0.310946256 Tfpt TCF3 (E2A) fusion partner K11670|1|1e-121|438|mmu:69714|TCF3 fusion partner GO:0000790//nuclear chromatin;GO:0015629//actin cytoskeleton;GO:0000790//nuclear chromatin;GO:0015629//actin cytoskeleton GO:0019900//kinase binding;GO:0046983//protein dimerization activity;GO:0019900//kinase binding;GO:0046983//protein dimerization activity "GO:0012502//induction of programmed cell death;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006351//transcription, DNA-templated;GO:0012502//induction of programmed cell death;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006351//transcription, DNA-templated" gi|594190794|ref|NP_001277310.1|/9.00289e-130/TCF3 fusion partner homolog isoform 1 [Mus musculus] 26357 2493 13.71333333 12.27 -0.160444044 Down 0.310946256 Abcg2 "ATP-binding cassette, sub-family G (WHITE), member 2" "K05681|1|0.0|1254|mmu:26357|ATP-binding cassette, subfamily G (WHITE), member 2" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044459 "GO:0032550;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0042802//identical protein binding" GO:0015893//drug transport;GO:0010038//response to metal ion;GO:0007565//female pregnancy;GO:0031960//response to corticosteroid;GO:0006082//organic acid metabolic process gi|6752944|ref|NP_036050.1|/0/ATP-binding cassette sub-family G member 2 [Mus musculus] 665934 1432 0.32 0.093333333 -1.777607579 Down 0.310852232 Gm7854 predicted gene 7854 - - - - "gi|148705637|gb|EDL37584.1|/1.67906e-38/mCG146113, partial [Mus musculus]" 16443 5588.73 17.03666667 15.31 -0.154168808 Down 0.310786415 Itsn1 intersectin 1 (SH3 domain protein 1A) K20045|1|0.0|2479|mmu:16443|intersectin "GO:0031252//cell leading edge;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0042995//cell projection;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0031252//cell leading edge;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0042995//cell projection;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0031252//cell leading edge;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0042995//cell projection;GO:0012505//endomembrane system;GO:0016020//membrane" GO:0008047//enzyme activator activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0046872//metal ion binding;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0046872//metal ion binding;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0046872//metal ion binding;GO:0008289//lipid binding;GO:0005515//protein binding GO:0016192//vesicle-mediated transport;GO:0044093;GO:0016310//phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0007266//Rho protein signal transduction;GO:0016192//vesicle-mediated transport;GO:0044093;GO:0016310//phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0007266//Rho protein signal transduction;GO:0016192//vesicle-mediated transport;GO:0044093;GO:0016310//phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0007266//Rho protein signal transduction gi|755554856|ref|XP_011244403.1|/1.34174e-161/PREDICTED: intersectin-1 isoform X11 [Mus musculus] 70784 2364.98 6.25 5.41 -0.208227596 Down 0.310777013 Rasl12 "RAS-like, family 12" K07854|1|9e-76|287|mmu:70784|Ras-like protein family member 12 - GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process gi|251823865|ref|NP_001028330.2|/4.32098e-147/ras-like protein family member 12 isoform 1 [Mus musculus] 226791 1577 0.843333333 1.226666667 0.540568381 Up 0.310692392 Lyplal1 lysophospholipase-like 1 K06999|1|8e-138|493|mmu:226791|phospholipase/carboxylesterase GO:0044444//cytoplasmic part GO:0003824//catalytic activity GO:0042996//regulation of Golgi to plasma membrane protein transport gi|227496223|ref|NP_666218.2|/6.85e-137/lysophospholipase-like protein 1 [Mus musculus] 100038713 4791 1.223333333 0.84 -0.542356329 Down 0.310692392 Gm10432 predicted gene 10432 - - - - - 20663 5612 9.49 8.403333333 -0.175446375 Down 0.310692392 Sos2 son of sevenless homolog 2 (Drosophila) K03099|1|0.0|2348|mmu:20663|son of sevenless GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0046983//protein dimerization activity GO:0012501//programmed cell death;GO:0006935//chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007266//Rho protein signal transduction gi|208022616|ref|NP_001129031.1|/0/son of sevenless homolog 2 [Mus musculus] 106014251 9228 3.49 4.153333333 0.251042626 Up 0.310532551 Rnf8-cmtr1 Rnf8-cmtr1 readthrough K14589|1|0.0|803|amj:102558730|cap1 methyltransferase [EC:2.1.1.57] - - - - 71653 4081 1.043333333 0.686666667 -0.60351832 Down 0.310504344 Shtn1 shootin 1 K10380|1|6e-10|69.7|xma:102237123|ankyrin;K10388|2|3e-08|63.9|xma:102237135|plectin;K10352|3|8e-08|62.8|phi:102105629|myosin heavy chain;K20478|5|1e-07|62.4|mde:101898828|golgin subfamily B member 1 GO:0043005//neuron projection;GO:0044444//cytoplasmic part;GO:0043005//neuron projection;GO:0044444//cytoplasmic part GO:0019899//enzyme binding;GO:0019899//enzyme binding GO:0006935//chemotaxis;GO:0031175//neuron projection development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006935//chemotaxis;GO:0031175//neuron projection development;GO:0048667//cell morphogenesis involved in neuron differentiation gi|60360078|dbj|BAD90258.1|/0/mKIAA1598 protein [Mus musculus] 328451 3224 167.28 181.91 0.120959886 Up 0.310438527 Gm5088 "poly(A)-binding protein, cytoplasmic pseudogene" K13126|1|0.0|1128|rno:298510|polyadenylate-binding protein GO:0035770//ribonucleoprotein granule GO:0036094//small molecule binding;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding - gi|568928951|ref|XP_006503084.1|/0/PREDICTED: polyadenylate-binding protein 4 isoform X2 [Mus musculus] 15078 1086 170.9866667 185.57 0.118079667 Up 0.310419722 H3f3a "H3 histone, family 3A" K11253|1|2e-71|271|fca:100169960|histone H3 - - - - 594843 485 0.323333333 0.096666667 -1.741931847 Down 0.31041032 Has2os "hyaluronan synthase 2, opposite strand" - - - - - 68232 543 0.776666667 0.453333333 -0.776723303 Down 0.310400918 1700120K04Rik RIKEN cDNA 1700120K04 gene - - - - gi|148685618|gb|EDL17565.1|/2.01321e-28/RIKEN cDNA 1700120K04 [Mus musculus] 57295 5001.03 11.01 9.8 -0.167960815 Down 0.310335101 Icmt isoprenylcysteine carboxyl methyltransferase K00587|1|1e-143|514|mmu:57295|protein-S-isoprenylcysteine O-methyltransferase [EC:2.1.1.100] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0003713//transcription coactivator activity;GO:0003880//protein C-terminal carboxyl O-methyltransferase activity;GO:0003713//transcription coactivator activity;GO:0003880//protein C-terminal carboxyl O-methyltransferase activity GO:0007265//Ras protein signal transduction;GO:0043009//chordate embryonic development;GO:0040007//growth;GO:0006790//sulfur compound metabolic process;GO:0006479//protein methylation;GO:0033036;GO:0008283//cell proliferation;GO:0007265//Ras protein signal transduction;GO:0043009//chordate embryonic development;GO:0040007//growth;GO:0006790//sulfur compound metabolic process;GO:0006479//protein methylation;GO:0033036;GO:0008283//cell proliferation gi|51317397|ref|NP_598549.1|/1.10709e-142/protein-S-isoprenylcysteine O-methyltransferase [Mus musculus] 20347 3790.05 9.95 11.16333333 0.165999445 Up 0.310335101 Sema3b "sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B" K06840|1|0.0|1449|mmu:20347|semaphorin 3 - - GO:0048731//system development;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0048869//cellular developmental process gi|112421073|ref|NP_033179.2|/0/semaphorin-3B precursor [Mus musculus] 666926 1374 0.47 0.206666667 -1.185355042 Down 0.310335101 Gm8369 predicted gene 8369 - - - - - 22247 3219 2.69 3.276666667 0.284622743 Up 0.310306894 Umps uridine monophosphate synthetase K13421|1|0.0|939|mmu:22247|uridine monophosphate synthetase [EC:2.4.2.10 4.1.1.23] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0016763//transferase activity, transferring pentosyl groups;GO:0016831//carboxy-lyase activity" GO:0044703;GO:0007589//body fluid secretion;GO:0006222//UMP biosynthetic process;GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0042493//response to drug gi|33859498|ref|NP_033497.1|/0/uridine 5'-monophosphate synthase [Mus musculus] 14828 2540.12 161.0566667 175.16 0.121104975 Up 0.310288089 Hspa5 heat shock protein 5 K09490|1|0.0|1224|mmu:14828|heat shock 70kDa protein 5 GO:0043234//protein complex;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0048770;GO:0043234//protein complex;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0048770 GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0046872//metal ion binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0043021//ribonucleoprotein complex binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0046872//metal ion binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0043021//ribonucleoprotein complex binding;GO:0044389//ubiquitin-like protein ligase binding GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001775//cell activation;GO:0070670//response to interleukin-4;GO:0006915//apoptotic process;GO:0006887//exocytosis;GO:0009790//embryo development;GO:0016567//protein ubiquitination;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0009154//purine ribonucleotide catabolic process;GO:0032268//regulation of cellular protein metabolic process;GO:0007599//hemostasis;GO:0009267//cellular response to starvation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0021695//cerebellar cortex development;GO:0021577//hindbrain structural organization;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001775//cell activation;GO:0070670//response to interleukin-4;GO:0006915//apoptotic process;GO:0006887//exocytosis;GO:0009790//embryo development;GO:0016567//protein ubiquitination;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0009154//purine ribonucleotide catabolic process;GO:0032268//regulation of cellular protein metabolic process;GO:0007599//hemostasis;GO:0009267//cellular response to starvation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0021695//cerebellar cortex development;GO:0021577//hindbrain structural organization gi|254540166|ref|NP_071705.3|/0/78 kDa glucose-regulated protein precursor [Mus musculus] 218490 909.49 155.5366667 169.32 0.122497668 Up 0.310165858 Btf3 basic transcription factor 3 K01527|1|3e-95|350|mmu:218490|nascent polypeptide-associated complex subunit beta GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding "GO:0006351//transcription, DNA-templated;GO:0043009//chordate embryonic development;GO:0006351//transcription, DNA-templated" gi|676274155|gb|KFO28711.1|/1.03161e-95/Transcription factor BTF3 [Fukomys damarensis] 53970 4189 1.603333333 2.07 0.368556374 Up 0.310165858 Rfx5 "regulatory factor X, 5 (influences HLA class II expression)" K08061|1|0.0|759|mmu:53970|regulatory factor X 5 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|7716046|gb|AAF68260.1|/0/regulator factor X 5 [Mus musculus] 66815 1332 0.57 0.913333333 0.680179568 Up 0.310128249 Ccdc109b coiled-coil domain containing 109B - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|651167847|ref|NP_001280573.1|/1.22176e-126/calcium uniporter regulatory subunit MCUb, mitochondrial isoform 2 [Mus musculus]" 100041874 2075 0.56 0.896666667 0.67914494 Up 0.310128249 Gm3558 predicted gene 3558 "K03844|1|2e-16|90.1|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - gi|755547055|ref|XP_011243076.1|/1.41799e-117/PREDICTED: uncharacterized protein Gm3173 isoform X1 [Mus musculus] 19009 4889.84 5.053333333 4.32 -0.226204035 Down 0.310118846 Pou6f1 "POU domain, class 6, transcription factor 1" "K09368|1|0.0|995|mmu:19009|POU domain transcription factor, class 6" GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|756761808|ref|NP_001291894.1|/0/POU domain, class 6, transcription factor 1 isoform 1 [Mus musculus]" 226778 4565 3.736666667 4.423333333 0.243382093 Up 0.310034225 Mark1 MAP/microtubule affinity regulating kinase 1 K08798|1|0.0|1439|mmu:226778|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] - - - - 77683 5015.13 5.486666667 4.713333333 -0.219182216 Down 0.309930798 Ehmt1 euchromatic histone methyltransferase 1 K11420|1|0.0|2412|mmu:77683|euchromatic histone-lysine N-methyltransferase [EC:2.1.1.43] - - - gi|157838004|ref|NP_001103156.1|/0/histone-lysine N-methyltransferase EHMT1 isoform 3 [Mus musculus] 18188 1023 9.333333333 10.53333333 0.174497731 Up 0.309799165 Nrtn neurturin K05452|1|8e-18|93.6|pbi:103067485|glial cell derived neurotrophic factor GO:0043005//neuron projection GO:0005102//receptor binding GO:0030030//cell projection organization;GO:0001667//ameboidal-type cell migration;GO:0006935//chemotaxis;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007399//nervous system development gi|6679136|ref|NP_032764.1|/8.33402e-57/neurturin precursor [Mus musculus] 239570 3766 11.99666667 13.40333333 0.159958234 Up 0.309770958 Ttc38 tetratricopeptide repeat domain 38 K19947|1|9e-94|348|xma:102228008|protein-methionine sulfoxide oxidase MICAL [EC:1.14.13.-];K13912|2|2e-13|81.3|bfo:BRAFLDRAFT_67122|deleted in malignant brain tumors 1 protein;K05476|3|9e-06|55.8|mmu:24099|tumor necrosis factor ligand superfamily member 13B - - - "gi|116283802|gb|AAH30849.1|/0/Ttc38 protein, partial [Mus musculus]" 66531 1440 24.21333333 22 -0.138298178 Down 0.309723946 Cmc2 COX assembly mitochondrial protein 2 K18172|1|1e-41|173|mmu:66531|COX assembly mitochondrial protein 2 GO:0043231//intracellular membrane-bounded organelle - - gi|33457314|ref|NP_081120.2|/1.06126e-40/COX assembly mitochondrial protein 2 homolog [Mus musculus] 68047 1701 36.73666667 40.27333333 0.132604158 Up 0.309705141 Mpnd MPN domain containing K11865|1|2e-21|106|xtr:100126685|protein MYSM1 - GO:0016787//hydrolase activity GO:0019538//protein metabolic process gi|74183910|dbj|BAE35755.1|/0/unnamed protein product [Mus musculus] 277154 7422 2.626666667 2.11 -0.31599013 Down 0.309695739 Nynrin NYN domain and retroviral integrase containing K18668|1|8e-39|166|asn:102369948|ribonuclease ZC3H12 [EC:3.1.-.-] GO:0031224//intrinsic component of membrane GO:0097159//organic cyclic compound binding GO:0006259//DNA metabolic process gi|256220954|ref|NP_001035161.1|/0/protein NYNRIN [Mus musculus] 20340 3880 17.04666667 15.35333333 -0.150937749 Down 0.309592313 Glg1 golgi apparatus protein 1 K06816|1|0.0|2144|mmu:20340|golgi apparatus protein 1 GO:0031224//intrinsic component of membrane;GO:0031985//Golgi cisterna;GO:0012505//endomembrane system GO:0019838//growth factor binding GO:0002062//chondrocyte differentiation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016485//protein processing;GO:0009653//anatomical structure morphogenesis;GO:0015031//protein transport gi|6677905|ref|NP_033175.1|/0/Golgi apparatus protein 1 precursor [Mus musculus] 68634 927.45 15.69333333 17.38333333 0.147552932 Up 0.309592313 Tm2d3 TM2 domain containing 3 K03511|1|2e-37|158|tsp:Tsp_01714|DNA polymerase kappa [EC:2.7.7.7] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|21312084|ref|NP_081071.1|/3.40835e-117/TM2 domain-containing protein 3 isoform 1 [Mus musculus] 434280 5092 0.633333333 0.98 0.629816737 Up 0.309498289 Gm5607 predicted gene 5607 K09267|1|1e-39|169|aam:106493919|transcription factor SOX1/3/14/21 (SOX group B) - - - "gi|42557306|gb|AAH66076.1|/7.44504e-110/Predicted gene, EG434280 [Mus musculus]" 56278 1547 13.71 12.31 -0.155397809 Down 0.30942307 Gkap1 G kinase anchoring protein 1 K10421|1|4e-07|58.9|dan:Dana_GF14794|CAP-Gly domain-containing linker protein 1;K04514|2|5e-07|58.5|xtr:100496057|Rho-associated protein kinase 1 [EC:2.7.11.1];K16481|5|7e-07|58.2|cmy:102946486|pericentrin GO:0043231//intracellular membrane-bounded organelle - "GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger" "gi|148709309|gb|EDL41255.1|/0/mCG6891, isoform CRA_a, partial [Mus musculus]" 22019 4683.94 10.58 9.393333333 -0.171630517 Down 0.309338448 Tpp2 tripeptidyl peptidase II K01280|1|0.0|2387|mmu:22019|tripeptidyl-peptidase II [EC:3.4.14.10] - - - gi|564368148|ref|XP_006244914.1|/0/PREDICTED: tripeptidyl-peptidase 2 isoform X1 [Rattus norvegicus] 269878 10040 9.43 10.62333333 0.171906842 Up 0.309338448 Megf8 multiple EGF-like-domains 8 "K10895|1|2e-20|105|aqu:100636243|fanconi anemia group I protein;K05637|4|1e-17|96.7|mze:101477084|laminin, alpha 1/2" - - - - 18139 6197.61 1.773333333 1.336666667 -0.407824009 Down 0.309263229 Zfp638 zinc finger protein 638 K13172|1|6e-18|97.1|mze:101468083|serine/arginine repetitive matrix protein 2;K13213|3|4e-13|81.3|cmk:103177266|matrin 3 - - - - 100039864 606 8.103333333 9.17 0.178406246 Up 0.309244424 Snhg12 small nucleolar RNA host gene 12 - - - - "gi|148698165|gb|EDL30112.1|/1.96826e-26/mCG16251, isoform CRA_a [Mus musculus]" 216505 2267 21.68 23.86 0.138229286 Up 0.309244424 Pik3ip1 phosphoinositide-3-kinase interacting protein 1 K01343|1|3e-08|63.2|gfr:102034369|tissue plasminogen activator [EC:3.4.21.68] GO:0031224//intrinsic component of membrane GO:0019900//kinase binding GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0009968//negative regulation of signal transduction "gi|148708463|gb|EDL40410.1|/1.49168e-166/RIKEN cDNA 1500004A08, isoform CRA_c, partial [Mus musculus]" 210808 2419 1.463333333 1.913333333 0.386829797 Up 0.309216217 Lacc1 laccase (multicopper oxidoreductase) domain containing 1 K05810|1|0.0|874|mmu:210808|laccase domain-containing protein - - - "gi|148703852|gb|EDL35799.1|/0/RIKEN cDNA 9030625A04, isoform CRA_b, partial [Mus musculus]" 20459 2286 0.42 0.17 -1.304854582 Down 0.30918801 Ptk6 PTK6 protein tyrosine kinase 6 K08894|1|0.0|945|mmu:20459|protein tyrosine kinase 6 [EC:2.7.10.2] GO:0043231//intracellular membrane-bounded organelle;GO:0031252//cell leading edge GO:0032550;GO:0004713//protein tyrosine kinase activity GO:0007260//tyrosine phosphorylation of STAT protein;GO:0040007//growth;GO:0032526//response to retinoic acid;GO:0006469//negative regulation of protein kinase activity;GO:0002065;GO:0010975//regulation of neuron projection development;GO:0048870//cell motility gi|6677971|ref|NP_033210.1|/0/protein-tyrosine kinase 6 [Mus musculus] 16776 11404 23.00666667 20.83333333 -0.143158284 Down 0.309065779 Lama5 "laminin, alpha 5" "K06240|1|0.0|7470|mmu:16776|laminin, alpha 3/5" GO:0043256//laminin complex GO:0005102//receptor binding GO:0090150//establishment of protein localization to membrane;GO:0042476//odontogenesis;GO:0030323//respiratory tube development;GO:0007435//salivary gland morphogenesis;GO:0010927;GO:0001667//ameboidal-type cell migration;GO:0008544//epidermis development;GO:0060562//epithelial tube morphogenesis;GO:0007155//cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0008283//cell proliferation;GO:0009790//embryo development;GO:0000904//cell morphogenesis involved in differentiation gi|124487155|ref|NP_001074640.1|/0/laminin subunit alpha-5 precursor [Mus musculus] 319178 490 0.01 0.163333333 4.029747343 Up 0.309009365 Hist1h2bb "histone cluster 1, H2bb" K11252|1|5e-43|175|pps:100984497|histone H2B - - - - 326619 455 0.163333333 0.01 -4.029747343 Down 0.309009365 Hist1h4a "histone cluster 1, H4a" K11254|1|5e-43|174|ecb:100068166|histone H4;K11253|5|8e-40|164|ecb:100052511|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|953881761|ref|XP_014590042.1|/3.76155e-42/PREDICTED: histone H4 [Equus caballus] 628100 1711 0.01 0.163333333 4.029747343 Up 0.309009365 Fbxo39 F-box protein 39 K10314|1|0.0|907|mmu:628100|F-box protein 39 - - - gi|537143087|gb|ERE68820.1|/0/F-box only protein 39 [Cricetulus griseus] 72215 639 0.163333333 0.01 -4.029747343 Down 0.309009365 1700001P01Rik RIKEN cDNA 1700001P01 gene - - - - gi|28913473|gb|AAH48607.1|/5.9644e-95/1700001P01Rik protein [Mus musculus] 76166 951 0.163333333 0.01 -4.029747343 Down 0.309009365 Rsg1 REM2 and RAB-like small GTPase 1 K07848|1|7e-08|60.5|acs:100555238|Rad and Gem related GTP binding protein 2;K07920|5|1e-07|59.7|xma:102236194|Ras-related protein Rab-33B GO:0043232;GO:0043231//intracellular membrane-bounded organelle GO:0032550 GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport;GO:0016043//cellular component organization gi|124487179|ref|NP_001074643.1|/2.63047e-147/REM2- and Rab-like small GTPase 1 [Mus musculus] 100041480 1660 0.01 0.163333333 4.029747343 Up 0.309009365 Gm9833 "myelin basic protein expression factor 2, repressor pseudogene" K12887|1|5e-82|307|pale:102887602|heterogeneous nuclear ribonucleoprotein M - - - - 231603 646 0.16 0.01 -4 Down 0.309009365 A630023P12Rik RIKEN cDNA A630023P12 gene - - - - "gi|148688069|gb|EDL20016.1|/7.0958e-84/RIKEN cDNA A630023P12, isoform CRA_a, partial [Mus musculus]" 546886 921 0.01 0.163333333 4.029747343 Up 0.309009365 Cfap73 cilia and flagella associated protein 73 K16307|1|2e-07|58.9|pale:102896178|serine/threonine-protein kinase MRCK [EC:2.7.11.1] - - - - 56365 2344 0.523333333 0.253333333 -1.046693235 Down 0.309009365 Clcnkb "chloride channel, voltage-sensitive Kb" K05018|1|0.0|1281|mmu:56365|chloride channel Kb;K05017|5|0.0|1101|rno:79425|chloride channel Ka GO:0034702//ion channel complex GO:0005488//binding;GO:0005254//chloride channel activity GO:0034220//ion transmembrane transport;GO:0006821//chloride transport gi|172072655|ref|NP_062675.2|/0/chloride channel protein ClC-Kb [Mus musculus] 11998 631 0.01 0.163333333 4.029747343 Up 0.309009365 Avp arginine vasopressin K05242|1|2e-82|306|mmu:11998|arginine vasopressin - - - - 78172 341 0.163333333 0.01 -4.029747343 Down 0.309009365 4930487D11Rik RIKEN cDNA 4930487D11 gene - - - - - 234729 3053 13.40666667 12.01666667 -0.157913822 Down 0.308943548 Vac14 Vac14 homolog (S. cerevisiae) K15305|1|0.0|1558|mmu:234729|vacuole morphology and inheritance protein 14 GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle GO:0008047//enzyme activator activity GO:0016310//phosphorylation "gi|148679516|gb|EDL11463.1|/0/Vac14 homolog (S. cerevisiae), isoform CRA_b, partial [Mus musculus]" 100504323 1551 1.003333333 1.403333333 0.484056746 Up 0.308896536 Gm20172 "predicted gene, 20172" - - - - gi|325995169|ref|NP_001191842.1|/3.63873e-58/uncharacterized protein LOC100504323 [Mus musculus] 214639 1390 1.393333333 0.996666667 -0.483357458 Down 0.308896536 4930486L24Rik RIKEN cDNA 4930486L24 gene K01365|1|1e-161|572|cge:100765299|cathepsin L [EC:3.4.22.15] - "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process "gi|148709357|gb|EDL41303.1|/0/RIKEN cDNA 4930486L24, partial [Mus musculus]" 68311 516 1.32 0.933333333 -0.500073603 Down 0.308849524 Lypd2 Ly6/Plaur domain containing 2 K06846|1|4e-13|75.9|xtr:101732565|lymphocyte antigen 6 complex locus protein D/E/G6/H GO:0031224//intrinsic component of membrane - - gi|110625683|ref|NP_080947.1|/2.75333e-55/ly6/PLAUR domain-containing protein 2 precursor [Mus musculus] 109323 1523.82 3.496666667 2.893333333 -0.27324773 Down 0.308840122 C1qtnf7 C1q and tumor necrosis factor related protein 7 K07296|1|2e-26|122|tgu:100221092|adiponectin GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix - GO:0051259//protein oligomerization;GO:0051259//protein oligomerization gi|564383957|ref|XP_006251135.1|/1.43897e-86/PREDICTED: complement C1q tumor necrosis factor-related protein 7 isoform X3 [Rattus norvegicus] 18733 2728 4.096666667 4.82 0.234582637 Up 0.308821317 Pirb paired Ig-like receptor B K06512|1|0.0|1599|mmu:18733|leukocyte immunoglobulin-like receptor GO:0031224//intrinsic component of membrane - GO:0001773//myeloid dendritic cell activation;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0007166//cell surface receptor signaling pathway;GO:0002449 gi|160333134|ref|NP_035225.2|/0/leukocyte immunoglobulin-like receptor subfamily B member 3 precursor [Mus musculus] 66226 1445.35 7.776666667 6.816666667 -0.190085464 Down 0.308708488 Trappc2 trafficking protein particle complex 2 K20301|1|4e-80|301|cfa:480840|trafficking protein particle complex subunit 2 - - - - 75778 1730 7.84 6.876666667 -0.189144239 Down 0.308708488 Them4 thioesterase superfamily member 4 K16339|1|2e-116|422|mmu:75778|thioesterase superfamily member 4 GO:0001726//ruffle;GO:0019866//organelle inner membrane;GO:0005740//mitochondrial envelope GO:0047617//acyl-CoA hydrolase activity GO:0012501//programmed cell death;GO:0044238//primary metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0048017//inositol lipid-mediated signaling;GO:0038127//ERBB signaling pathway gi|110626050|ref|NP_083707.1|/1.28388e-115/acyl-coenzyme A thioesterase THEM4 [Mus musculus] 170748 954 7.883333333 8.94 0.181469054 Up 0.308699086 Smco4 single-pass membrane protein with coiled-coil domains 4 - GO:0031224//intrinsic component of membrane - - "gi|148693083|gb|EDL25030.1|/3.84389e-29/cDNA sequence BC017612, isoform CRA_a [Mus musculus]" 214579 5647 9.05 7.99 -0.179722289 Down 0.308699086 Aldh5a1 "aldhehyde dehydrogenase family 5, subfamily A1" K00139|1|0.0|972|mmu:214579|succinate-semialdehyde dehydrogenase [EC:1.2.1.24] GO:0043231//intracellular membrane-bounded organelle "GO:0043168//anion binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding" GO:0006644//phospholipid metabolic process;GO:0022900//electron transport chain;GO:0006631//fatty acid metabolic process;GO:0043648//dicarboxylic acid metabolic process;GO:0019318//hexose metabolic process;GO:0042133//neurotransmitter metabolic process;GO:0006790//sulfur compound metabolic process;GO:0051260//protein homooligomerization;GO:0009064//glutamine family amino acid metabolic process;GO:0006677//glycosylceramide metabolic process;GO:0007399//nervous system development;GO:0009063//cellular amino acid catabolic process "gi|27369748|ref|NP_766120.1|/0/succinate-semialdehyde dehydrogenase, mitochondrial precursor [Mus musculus]" 20853 3623.99 21.89333333 24.04333333 0.135145297 Up 0.308689684 Stau1 staufen (RNA binding protein) homolog 1 (Drosophila) K17597|1|0.0|629|mmu:20853|double-stranded RNA-binding protein Staufen GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0044297//cell body;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0044297//cell body;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0044297//cell body;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0044297//cell body;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0044297//cell body;GO:0042995//cell projection GO:0003723//RNA binding;GO:0019903//protein phosphatase binding;GO:0003723//RNA binding;GO:0019903//protein phosphatase binding;GO:0003723//RNA binding;GO:0019903//protein phosphatase binding;GO:0003723//RNA binding;GO:0019903//protein phosphatase binding;GO:0003723//RNA binding;GO:0019903//protein phosphatase binding GO:0006403//RNA localization;GO:0006403//RNA localization;GO:0006403//RNA localization;GO:0006403//RNA localization;GO:0006403//RNA localization gi|74198409|dbj|BAE39688.1|/0/unnamed protein product [Mus musculus] 268670 3482 0.73 0.416666667 -0.809002775 Down 0.30855805 Zfp759 zinc finger protein 759 K09228|1|0.0|973|rno:102551340|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|119226195|ref|NP_765980.3|/0/zinc finger protein 759 [Mus musculus] 67204 2513 23.58666667 21.45 -0.1369939 Down 0.308511038 Eif2s2 "eukaryotic translation initiation factor 2, subunit 2 (beta)" K03238|1|1e-157|560|mmu:67204|translation initiation factor 2 subunit 2 - "GO:0008135//translation factor activity, RNA binding;GO:0043169//cation binding" GO:0036093//germ cell proliferation;GO:0006412//translation;GO:0008406//gonad development gi|14149756|ref|NP_080306.1|/8.19075e-157/eukaryotic translation initiation factor 2 subunit 2 [Mus musculus] 16647 2071 38.03333333 34.68333333 -0.133021827 Down 0.308464026 Kpna2 karyopherin (importin) alpha 2 K15043|1|0.0|1014|mmu:16647|importin subunit alpha-2 GO:0043231//intracellular membrane-bounded organelle GO:0022892//substrate-specific transporter activity;GO:0005048//signal sequence binding;GO:0019899//enzyme binding GO:0006606//protein import into nucleus;GO:0045990//carbon catabolite regulation of transcription gi|6754474|ref|NP_034785.1|/0/importin subunit alpha-1 [Mus musculus] 27357 1736 123.0533333 133.5066667 0.117628046 Up 0.308426417 Gyg glycogenin K00750|1|0.0|684|cge:100751671|glycogenin glucosyltransferase [EC:2.4.1.186] - GO:0043169//cation binding;GO:0035251//UDP-glucosyltransferase activity GO:0005977//glycogen metabolic process gi|568920942|ref|XP_006535544.1|/0/PREDICTED: glycogenin-1 isoform X1 [Mus musculus] 50496 2472.12 35.76333333 39.10333333 0.128810385 Up 0.308407612 E2f6 E2F transcription factor 6 K09390|1|2e-148|528|mmu:50496|transcription factor E2F6 GO:0044665//MLL1/2 complex;GO:0044665//MLL1/2 complex GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0044763;GO:0006351//transcription, DNA-templated;GO:0044763;GO:0006351//transcription, DNA-templated" gi|237681138|ref|NP_150373.2|/2.02214e-147/transcription factor E2F6 [Mus musculus] 100040030 902 0.116666667 0.35 1.584962501 Up 0.308388807 Gm2560 predicted gene 2560 - - - - - 58246 3697 3.35 2.766666667 -0.27601226 Down 0.3083606 Slc35b4 "solute carrier family 35, member B4" "K15278|1|2e-178|629|mmu:58246|solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system GO:0015165//pyrimidine nucleotide-sugar transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity GO:0044763;GO:0015711//organic anion transport;GO:0006094//gluconeogenesis gi|10946804|ref|NP_067410.1|/1.31061e-177/UDP-xylose and UDP-N-acetylglucosamine transporter [Mus musculus] 94226 2512 0.366666667 0.67 0.869691978 Up 0.308313588 S1pr5 sphingosine-1-phosphate receptor 5 K04295|1|2e-141|506|mmu:94226|sphingosine 1-phosphate receptor 5 - - - - 56078 3465 1.406666667 1.85 0.395244773 Up 0.308313588 Car5b "carbonic anhydrase 5b, mitochondrial" K01672|1|0.0|669|mmu:56078|carbonic anhydrase [EC:4.2.1.1] GO:0044429 GO:0046914//transition metal ion binding;GO:0016836//hydro-lyase activity GO:0044237//cellular metabolic process;GO:0015711//organic anion transport;GO:0044710 "gi|148708817|gb|EDL40764.1|/0/carbonic anhydrase 5b, mitochondrial, partial [Mus musculus]" 269400 4433 2.26 1.776666667 -0.34714974 Down 0.308285381 Rtel1 regulator of telomere elongation helicase 1 K11136|1|0.0|2014|mmu:269400|regulator of telomere elongation helicase 1 [EC:3.6.4.12] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0003678//DNA helicase activity;GO:0043169//cation binding;GO:0032550;GO:0051536//iron-sulfur cluster binding;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0003678//DNA helicase activity;GO:0043169//cation binding;GO:0032550;GO:0051536//iron-sulfur cluster binding;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0003678//DNA helicase activity;GO:0043169//cation binding;GO:0032550;GO:0051536//iron-sulfur cluster binding;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0003678//DNA helicase activity;GO:0043169//cation binding;GO:0032550;GO:0051536//iron-sulfur cluster binding;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0003678//DNA helicase activity;GO:0043169//cation binding;GO:0032550;GO:0051536//iron-sulfur cluster binding;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0003678//DNA helicase activity;GO:0043169//cation binding;GO:0032550;GO:0051536//iron-sulfur cluster binding;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled" GO:0033554//cellular response to stress;GO:0000018//regulation of DNA recombination;GO:0033554//cellular response to stress;GO:0000018//regulation of DNA recombination;GO:0033554//cellular response to stress;GO:0000018//regulation of DNA recombination;GO:0033554//cellular response to stress;GO:0000018//regulation of DNA recombination;GO:0033554//cellular response to stress;GO:0000018//regulation of DNA recombination;GO:0033554//cellular response to stress;GO:0000018//regulation of DNA recombination gi|568920264|ref|XP_006500700.1|/0/PREDICTED: regulator of telomere elongation helicase 1 isoform X2 [Mus musculus] 56745 4390.62 9.2 10.37333333 0.173173793 Up 0.308285381 C1qtnf1 C1q and tumor necrosis factor related protein 1 K19470|1|3e-77|293|amj:102568174|complement C1q tumor necrosis factor-related protein 6 GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix - GO:0051291//protein heterooligomerization;GO:0006006//glucose metabolic process;GO:0000165//MAPK cascade;GO:0051291//protein heterooligomerization;GO:0006006//glucose metabolic process;GO:0000165//MAPK cascade;GO:0051291//protein heterooligomerization;GO:0006006//glucose metabolic process;GO:0000165//MAPK cascade gi|568974999|ref|XP_006533883.1|/3.98379e-149/PREDICTED: complement C1q tumor necrosis factor-related protein 1 isoform X2 [Mus musculus] 72351 2064 0.58 0.916666667 0.660344313 Up 0.308247772 Ptar1 protein prenyltransferase alpha subunit repeat containing 1 K14137|1|0.0|847|mmu:72351|protein prenyltransferase alpha subunit repeat containing protein 1 - - GO:0006464//cellular protein modification process gi|258613904|ref|NP_082484.1|/0/protein prenyltransferase alpha subunit repeat-containing protein 1 [Mus musculus] 67669 1047.85 20.37333333 22.49666667 0.14302921 Up 0.308172553 l7Rn6 "lethal, Chr 7, Rinchik 6" - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0031072//heat shock protein binding;GO:0022892//substrate-specific transporter activity;GO:0031072//heat shock protein binding;GO:0022892//substrate-specific transporter activity;GO:0031072//heat shock protein binding;GO:0022892//substrate-specific transporter activity;GO:0031072//heat shock protein binding;GO:0022892//substrate-specific transporter activity;GO:0031072//heat shock protein binding;GO:0022892//substrate-specific transporter activity GO:0030323//respiratory tube development;GO:0006996//organelle organization;GO:0009408//response to heat;GO:0006886//intracellular protein transport;GO:0030323//respiratory tube development;GO:0006996//organelle organization;GO:0009408//response to heat;GO:0006886//intracellular protein transport;GO:0030323//respiratory tube development;GO:0006996//organelle organization;GO:0009408//response to heat;GO:0006886//intracellular protein transport;GO:0030323//respiratory tube development;GO:0006996//organelle organization;GO:0009408//response to heat;GO:0006886//intracellular protein transport;GO:0030323//respiratory tube development;GO:0006996//organelle organization;GO:0009408//response to heat;GO:0006886//intracellular protein transport gi|602617453|ref|NP_001278215.1|/4.82953e-97/protein Hikeshi isoform b [Mus musculus] 100043133 3581 2.103333333 1.636666667 -0.361916981 Down 0.308153748 9130023H24Rik RIKEN cDNA 9130023H24 gene K09228|1|2e-93|347|pss:102456868|KRAB domain-containing zinc finger protein - - - - 59032 2395 7.81 8.863333333 0.182526823 Up 0.308069126 Ppp2r3c "protein phosphatase 2, regulatory subunit B'', gamma" K11583|1|0.0|891|mmu:59032|serine/threonine-protein phosphatase 2A regulatory subunit B'' GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding - gi|31560309|ref|NP_067504.2|/0/serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma [Mus musculus] 574402 5209 3.026666667 2.47 -0.293218755 Down 0.308059724 Gpr17 G protein-coupled receptor 17 K08404|1|0.0|650|mmu:574402|G protein-coupled receptor 17 GO:0031224//intrinsic component of membrane GO:0001608 GO:0035588 gi|71725394|ref|NP_001020552.1|/0/uracil nucleotide/cysteinyl leukotriene receptor [Mus musculus] 432777 1306 0.533333333 0.266666667 -1 Down 0.308031517 D630045M09Rik RIKEN cDNA D630045M09 gene K04613|1|2e-09|66.2|rno:297590|vomeronasal 2 receptor - - - - 234967 1937 0.536666667 0.266666667 -1.008988783 Down 0.308031517 Slc36a4 "solute carrier family 36 (proton/amino acid symporter), member 4" K14209|1|0.0|992|mmu:234967|solute carrier family 36 (proton-coupled amino acid transporter) GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0006812//cation transport;GO:0015807//L-amino acid transport gi|31982042|ref|NP_758493.2|/0/proton-coupled amino acid transporter 4 [Mus musculus] 226432 6236 7.636666667 6.683333333 -0.192375222 Down 0.30800331 Ipo9 importin 9 K20224|1|0.0|1951|mmu:226432|importin-9 GO:0005635//nuclear envelope GO:0022892//substrate-specific transporter activity;GO:0017016//Ras GTPase binding GO:0006886//intracellular protein transport gi|112734861|ref|NP_722469.1|/0/importin-9 [Mus musculus] 67933 2386 7.723333333 6.773333333 -0.189357642 Down 0.30800331 Hcfc2 host cell factor C2 K14966|1|0.0|1468|mmu:67933|host cell factor GO:0043231//intracellular membrane-bounded organelle - - gi|568968324|ref|XP_006514074.1|/0/PREDICTED: host cell factor 2 isoform X2 [Mus musculus] 114128 1897 33.86 37.14333333 0.133521319 Up 0.307984505 Laptm4b lysosomal-associated protein transmembrane 4B K12387|1|5e-100|367|mmu:114128|lysosomal-associated transmembrane protein GO:0016020//membrane GO:0005488//binding - gi|15743550|ref|NP_277056.1|/4.2236e-99/lysosomal-associated transmembrane protein 4B [Mus musculus] 67916 3162 34.57333333 37.85 0.130633595 Up 0.307984505 Plpp3 phospholipid phosphatase 3 K01080|1|1e-161|573|mmu:67916|phosphatidate phosphatase [EC:3.1.3.4] - - - - 68260 4133 1.113333333 1.523333333 0.452346063 Up 0.307937493 Trmt12 tRNA methyltranferase 12 K07055|1|0.0|923|mmu:68260|tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114] - GO:0016741 GO:0006399//tRNA metabolic process gi|118150645|ref|NP_080918.2|/0/tRNA wybutosine-synthesizing protein 2 homolog [Mus musculus] 319618 3311 1.113333333 1.523333333 0.452346063 Up 0.307937493 Dcp1b decapping mRNA 1B K12611|1|0.0|1063|mmu:319618|mRNA-decapping enzyme 1B [EC:3.-.-.-] - - - - 17122 1194 39.28333333 36.01333333 -0.125386214 Down 0.307890481 Mxd4 Max dimerization protein 4 K09114|1|6e-89|330|mmu:17122|MAX dimerization protein GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding "GO:0006351//transcription, DNA-templated" gi|880877563|ref|XP_005068933.2|/1.00899e-91/PREDICTED: max dimerization protein 4 [Mesocricetus auratus] 67188 1641 1.043333333 1.443333333 0.468204368 Up 0.307787055 2700046G09Rik RIKEN cDNA 2700046G09 gene - - - - gi|26330856|dbj|BAC29158.1|/2.15353e-64/unnamed protein product [Mus musculus] 26446 731 112.1333333 121.7833333 0.119101502 Up 0.307777652 Psmb3 "proteasome (prosome, macropain) subunit, beta type 3" K02735|1|2e-115|416|aml:100471505|20S proteasome subunit beta 3 [EC:3.4.25.1] GO:0031981//nuclear lumen;GO:0000502//proteasome complex;GO:0044444//cytoplasmic part GO:0004175//endopeptidase activity "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0006915//apoptotic process;GO:0051320;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|752394223|ref|XP_011220101.1|/1.77539e-114/PREDICTED: proteasome subunit beta type-3 [Ailuropoda melanoleuca] 67045 3201 22.48333333 20.38666667 -0.141230036 Down 0.30773064 Riok2 RIO kinase 2 (yeast) K07179|1|0.0|1026|mmu:67045|RIO kinase 2 [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|13385428|ref|NP_080210.1|/0/serine/threonine-protein kinase RIO2 [Mus musculus] 69674 1456.8 20.84 22.94 0.138510114 Up 0.30773064 Mif4gd MIF4G domain containing - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding GO:0006412//translation;GO:0006412//translation gi|343790916|ref|NP_001230515.1|/6.18501e-101/MIF4G domain-containing protein isoform 2 [Mus musculus] 59048 1507 3.74 3.13 -0.256875613 Down 0.307683629 C1galt1c1 C1GALT1-specific chaperone 1 K09653|1|0.0|650|mmu:59048|C1GALT1-specific chaperone 1 [EC:2.4.1.-] GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane GO:0008376//acetylgalactosaminyltransferase activity GO:0006493//protein O-linked glycosylation gi|10946990|ref|NP_067525.1|/0/C1GALT1-specific chaperone 1 [Mus musculus] 75212 1502 9.256666667 10.41333333 0.169867276 Up 0.307683629 Rnf121 ring finger protein 121 K15698|1|9e-174|612|rno:308871|RING finger protein 121 GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding - gi|157820167|ref|NP_001101010.1|/7.27489e-173/RING finger protein 121 [Rattus norvegicus] 68576 905 33.85666667 37.08333333 0.13133099 Up 0.307674226 Lamtor5 "late endosomal/lysosomal adaptor, MAPK and MTOR activator 5" K16344|1|1e-78|295|mmu:68576|ragulator complex protein LAMTOR5 GO:0000323//lytic vacuole;GO:0031902//late endosome membrane - GO:0009967//positive regulation of signal transduction;GO:0006915//apoptotic process;GO:0032535//regulation of cellular component size;GO:0072665//protein localization to vacuole;GO:0019058//viral life cycle;GO:0043200//response to amino acid gi|237820655|ref|NP_081050.2|/1.17774e-77/ragulator complex protein LAMTOR5 [Mus musculus] 231876 8114 6.06 5.253333333 -0.206084665 Down 0.307674226 Lmtk2 lemur tyrosine kinase 2 K08898|1|0.0|2573|mmu:231876|lemur tyrosine kinase 2 [EC:2.7.10.1] GO:0031224//intrinsic component of membrane;GO:0005768//endosome GO:0032550;GO:0004672//protein kinase activity;GO:0017022//myosin binding;GO:0019212//phosphatase inhibitor activity GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0006468//protein phosphorylation;GO:0044092//negative regulation of molecular function;GO:0023051//regulation of signaling gi|124487401|ref|NP_001074578.1|/0/serine/threonine-protein kinase LMTK2 precursor [Mus musculus] 380752 1692 4.57 5.323333333 0.220135742 Up 0.307617812 Tssc1 tumor suppressing subtransferable candidate 1 K10752|1|1e-11|74.3|loa:LOAG_03438|histone-binding protein RBBP4;K13341|3|2e-11|73.2|spu:586615|peroxin-7 - - - "gi|148705000|gb|EDL36947.1|/0/tumor suppressing subtransferable candidate 1, isoform CRA_c, partial [Mus musculus]" 66471 3270.11 20.27666667 22.36333333 0.141314739 Up 0.307580202 Anp32e "acidic (leucine-rich) nuclear phosphoprotein 32 family, member E" K18648|1|8e-78|295|rno:361999|acidic leucine-rich nuclear phosphoprotein 32 family member E GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004857//enzyme inhibitor activity;GO:0004857//enzyme inhibitor activity;GO:0004857//enzyme inhibitor activity GO:0044092//negative regulation of molecular function;GO:0044092//negative regulation of molecular function;GO:0044092//negative regulation of molecular function "gi|148706910|gb|EDL38857.1|/1.73029e-85/acidic (leucine-rich) nuclear phosphoprotein 32 family, member E, isoform CRA_b, partial [Mus musculus]" 101513 1456 21.13666667 23.22333333 0.135827186 Up 0.307580202 Mob2 MOB kinase activator 2 K06685|1|5e-40|167|xla:398675|MOB kinase activator 1 GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen GO:0043169//cation binding - gi|20149310|ref|NP_082584.1|/1.05073e-136/MOB kinase activator 2 [Mus musculus] 12315 2233 104.34 113.7066667 0.124024504 Up 0.307561398 Calm3 calmodulin 3 K02183|1|1e-78|296|cmk:103189661|calmodulin - - - gi|744616901|ref|XP_010996006.1|/5.30411e-83/PREDICTED: calmodulin [Camelus dromedarius] 66650 1823 0.956666667 1.346666667 0.493304556 Up 0.307551995 Nepn nephrocan K06260|1|7e-27|124|ngi:103738869|platelet glycoprotein V GO:0005578//proteinaceous extracellular matrix - GO:0043062//extracellular structure organization;GO:0007179//transforming growth factor beta receptor signaling pathway gi|568965574|ref|XP_006512881.1|/0/PREDICTED: nephrocan isoform X1 [Mus musculus] 214547 5745 4.83 4.123333333 -0.228212095 Down 0.307551995 She src homology 2 domain-containing transforming protein E K08888|1|5e-08|63.9|mze:101468703|megakaryocyte-associated tyrosine kinase [EC:2.7.10.2];K06619|2|1e-07|62.8|sko:100374571|abelson tyrosine-protein kinase 1 [EC:2.7.10.2] - - - gi|74185931|dbj|BAE34127.1|/0/unnamed protein product [Mus musculus] 20509 2342.35 1.596666667 2.056666667 0.365244833 Up 0.307476776 Slc19a1 "solute carrier family 19 (folate transporter), member 1" "K14609|1|0.0|980|mmu:20509|solute carrier family 19 (folate transporter), member 1" GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane GO:0090484;GO:0019842//vitamin binding;GO:0015291//secondary active transmembrane transporter activity;GO:0090484;GO:0019842//vitamin binding;GO:0015291//secondary active transmembrane transporter activity GO:0006835//dicarboxylic acid transport;GO:0044703;GO:0006835//dicarboxylic acid transport;GO:0044703 gi|13654260|ref|NP_112473.1|/0/folate transporter 1 [Mus musculus] 54188 1722 7.783333333 8.82 0.180390512 Up 0.307448569 Cpsf4 cleavage and polyadenylation specific factor 4 K14404|1|1e-115|419|mmu:54188|cleavage and polyadenylation specificity factor subunit 4 GO:0005849//mRNA cleavage factor complex;GO:0005849//mRNA cleavage factor complex;GO:0005849//mRNA cleavage factor complex GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0006396//RNA processing;GO:0019054//modulation by virus of host process;GO:0006396//RNA processing;GO:0019054//modulation by virus of host process;GO:0006396//RNA processing;GO:0019054//modulation by virus of host process gi|601983907|ref|NP_001278177.1|/4.68171e-134/cleavage and polyadenylation specificity factor subunit 4 isoform a [Mus musculus] 64451 6370 2.426666667 1.926666667 -0.332868958 Down 0.307410959 Dip2a disco interacting protein 2 homolog A - - - - - 20977 2482 1.916666667 2.413333333 0.332427741 Up 0.307410959 Syp synaptophysin K14168|1|2e-23|113|fpg:101912737|cytoplasmic tRNA 2-thiolation protein 1 [EC:2.7.7.-] GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0030672//synaptic vesicle membrane;GO:0097060//synaptic membrane GO:0032934//sterol binding;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0019905//syntaxin binding GO:0016192//vesicle-mediated transport;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0010256//endomembrane system organization;GO:0048168//regulation of neuronal synaptic plasticity;GO:0016050//vesicle organization;GO:0010033//response to organic substance gi|1208521|emb|CAA65084.1|/2.0036e-123/synaptophysin [Mus musculus] 81896 4080.16 3.346666667 3.99 0.253663883 Up 0.307401557 Ift122 intraflagellar transport 122 K19656|1|0.0|2377|mmu:81896|intraflagellar transport protein 122 GO:0030990//intraciliary transport particle;GO:0043232;GO:0031513//nonmotile primary cilium;GO:0030990//intraciliary transport particle;GO:0043232;GO:0031513//nonmotile primary cilium - GO:0007224//smoothened signaling pathway;GO:0003002//regionalization;GO:0043010//camera-type eye development;GO:0048858//cell projection morphogenesis;GO:0010171//body morphogenesis;GO:0030326//embryonic limb morphogenesis;GO:0007224//smoothened signaling pathway;GO:0003002//regionalization;GO:0043010//camera-type eye development;GO:0048858//cell projection morphogenesis;GO:0010171//body morphogenesis;GO:0030326//embryonic limb morphogenesis "gi|148667127|gb|EDK99543.1|/0/intraflagellar transport 122 homolog (Chlamydomonas), isoform CRA_c, partial [Mus musculus]" 11974 800 34.30333333 37.50666667 0.128798279 Up 0.307392155 Atp6v0e "ATPase, H+ transporting, lysosomal V0 subunit E" K02153|1|3e-44|180|ngi:103748196|V-type H+-transporting ATPase subunit e GO:0030666//endocytic vesicle membrane;GO:0031224//intrinsic component of membrane;GO:0033176//proton-transporting V-type ATPase complex GO:0019829//cation-transporting ATPase activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity "GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0040007//growth;GO:0015031//protein transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006996//organelle organization;GO:0001101//response to acid chemical;GO:0051452//intracellular pH reduction;GO:0044403//symbiosis, encompassing mutualism through parasitism;GO:0006875//cellular metal ion homeostasis" gi|13384606|ref|NP_079548.1|/2.58325e-43/V-type proton ATPase subunit e 1 [Mus musculus] 20733 1311.12 19.73666667 21.82 0.144772749 Up 0.307382752 Spint2 "serine protease inhibitor, Kunitz type 2" K15619|1|4e-27|125|tru:101073645|Kunitz-type protease inhibitor 1 GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424 GO:0030414//peptidase inhibitor activity;GO:0030414//peptidase inhibitor activity GO:0051346//negative regulation of hydrolase activity;GO:0051346//negative regulation of hydrolase activity "gi|148692122|gb|EDL24069.1|/2.07781e-133/serine protease inhibitor, Kunitz type 2, isoform CRA_a, partial [Mus musculus]" 75597 696 22.00666667 19.93 -0.142998928 Down 0.307382752 Ndufaf2 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2" K18160|1|2e-87|323|mmu:75597|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 GO:0043231//intracellular membrane-bounded organelle GO:0050136//NADH dehydrogenase (quinone) activity GO:0044710 "gi|148686508|gb|EDL18455.1|/8.22258e-95/mCG10234, isoform CRA_b, partial [Mus musculus]" 13690 7757.82 115.3066667 106.3233333 -0.117017687 Down 0.307213509 Eif4g2 "eukaryotic translation initiation factor 4, gamma 2" K03260|1|0.0|1506|cge:100758677|translation initiation factor 4G - - - - 69944 4966 0.663333333 0.366666667 -0.855264907 Down 0.307185302 2810021J22Rik RIKEN cDNA 2810021J22 gene K09228|1|0.0|1140|mmu:69944|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|27369519|ref|NP_765991.1|/0/uncharacterized protein LOC69944 [Mus musculus] 66585 1613 9.04 10.19 0.172759374 Up 0.307166497 Snrnp40 small nuclear ribonucleoprotein 40 (U5) K12857|1|0.0|658|mmu:66585|Prp8 binding protein GO:0005681//spliceosomal complex - GO:0006396//RNA processing gi|115298670|ref|NP_079921.2|/0/U5 small nuclear ribonucleoprotein 40 kDa protein [Mus musculus] 329753 4188 1.266666667 0.886666667 -0.514573173 Down 0.307110083 9830132P13Rik RIKEN cDNA 9830132P13 gene - - - - - 12765 3043 2.92 3.513333333 0.266872092 Up 0.307091278 Cxcr2 chemokine (C-X-C motif) receptor 2 K05050|1|0.0|685|mmu:12765|interleukin 8 receptor beta GO:0005764//lysosome;GO:0031224//intrinsic component of membrane GO:0019958//C-X-C chemokine binding;GO:0016494//C-X-C chemokine receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0002274;GO:0012501//programmed cell death;GO:0006898//receptor-mediated endocytosis;GO:0008283//cell proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0006171//cAMP biosynthetic process;GO:0006952//defense response;GO:0030595//leukocyte chemotaxis gi|6753456|ref|NP_034039.1|/0/C-X-C chemokine receptor type 2 [Mus musculus] 219144 1505 0.796666667 0.476666667 -0.740995471 Down 0.307081876 Arl11 ADP-ribosylation factor-like 11 K07959|1|1e-87|326|mmu:219144|ADP-ribosylation factor-like protein 11 GO:0044464 GO:0032550 GO:0035556//intracellular signal transduction gi|42476058|ref|NP_796311.2|/1.0443e-86/ADP-ribosylation factor-like protein 11 [Mus musculus] 100039043 1810 0.156666667 0.01 -3.969626351 Down 0.307044266 Gm10731 FUN14 domain containing 2 pseudogene K17986|1|7e-46|187|clv:102091908|FUN14 domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle - - gi|109730699|gb|AAI17740.1|/2.27071e-86/RIKEN cDNA 1700034I23 gene [Mus musculus] 77705 658 0.01 0.156666667 3.969626351 Up 0.307044266 9230104L09Rik RIKEN cDNA 9230104L09 gene K13905|1|2e-29|130|ngi:103731651|cystatin-9 - - GO:0006950//response to stress gi|58037501|ref|NP_084236.1|/1.63304e-70/cystatin E2 precursor [Mus musculus] 546723 836 0.01 0.156666667 3.969626351 Up 0.307044266 Ppp1r2-ps3 "protein phosphatase 1, regulatory (inhibitor) subunit 2, pseudogene 3" K16833|1|4e-93|343|mmu:66849|protein phosphatase inhibitor 2 - GO:0019212//phosphatase inhibitor activity GO:0010921//regulation of phosphatase activity;GO:0006073//cellular glucan metabolic process;GO:0007165//signal transduction;GO:0044092//negative regulation of molecular function gi|148709760|gb|EDL41706.1|/4.39754e-97/mCG142426 [Mus musculus] 224840 1718 0.01 0.156666667 3.969626351 Up 0.307044266 Treml4 triggering receptor expressed on myeloid cells-like 4 K06742|1|4e-27|125|ecb:100066291|natural cytotoxicity triggering receptor 2 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148691658|gb|EDL23605.1|/2.15445e-139/triggering receptor expressed on myeloid cells-like 4, isoform CRA_b, partial [Mus musculus]" 19848 187 1.926666667 1.476666667 -0.383762794 Down 0.307034864 Rnu2-10 U2 small nuclear RNA 10 - - - - gi|24940209|emb|CAA24954.2|/1.74655e-10/unnamed protein product [Xenopus laevis] 11845 3740 11.63333333 12.97666667 0.157655308 Up 0.306997255 Arf6 ADP-ribosylation factor 6 K07941|1|2e-97|360|oaa:100077992|ADP-ribosylation factor 6 GO:0031090//organelle membrane;GO:0031252//cell leading edge;GO:0030175//filopodium;GO:0005768//endosome GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0019899//enzyme binding GO:0030010//establishment of cell polarity;GO:0050773//regulation of dendrite development;GO:0006898//receptor-mediated endocytosis;GO:0009154//purine ribonucleotide catabolic process;GO:0016601//Rac protein signal transduction;GO:0001702//gastrulation with mouth forming second;GO:0022610;GO:0045184//establishment of protein localization;GO:0046847//filopodium assembly;GO:0030041//actin filament polymerization;GO:0034613//cellular protein localization;GO:0012501//programmed cell death;GO:0051130//positive regulation of cellular component organization;GO:0034121//regulation of toll-like receptor signaling pathway gi|918582418|ref|XP_005376889.2|/9.10437e-110/PREDICTED: ADP-ribosylation factor 6 [Chinchilla lanigera] 19286 1051 19.56333333 21.61333333 0.143769383 Up 0.306809207 Pts 6-pyruvoyl-tetrahydropterin synthase K01737|1|4e-66|254|mmu:19286|6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] GO:0043231//intracellular membrane-bounded organelle GO:0042802//identical protein binding;GO:0016838;GO:0043169//cation binding GO:0009108//coenzyme biosynthetic process gi|4321787|gb|AAD15827.1|/2.95032e-65/6-pyruvoyl-tetrahydropterin synthase [Mus musculus] 64099 2655 0.426666667 0.74 0.794415866 Up 0.306809207 Parvg "parvin, gamma" K06275|1|6e-176|620|mmu:64099|parvin - - - gi|244790018|ref|NP_001155972.1|/0/gamma-parvin isoform 1 [Mus musculus] 227683 1987 7.606666667 8.64 0.183766927 Up 0.30674339 Coq4 coenzyme Q4 K18586|1|2e-131|472|mmu:227683|ubiquinone biosynthesis protein COQ4 - - - - 13709 4046.77 5.88 5.083333333 -0.210041318 Down 0.306677573 Elf1 E74-like factor 1 K09428|1|0.0|1055|mmu:13709|E74-like factor 1/2/4 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0050852//T cell receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0001816//cytokine production;GO:0050852//T cell receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0001816//cytokine production;GO:0050852//T cell receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0001816//cytokine production gi|6679627|ref|NP_031946.1|/0/ETS-related transcription factor Elf-1 isoform 1 [Mus musculus] 66359 448 95.28 103.6166667 0.12101076 Up 0.306649366 Cox20 COX20 Cox2 chaperone K18184|1|2e-63|242|mmu:66359|cytochrome c oxidase assembly protein subunit 20 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|21313516|ref|NP_079787.1|/1.48005e-62/cytochrome c oxidase protein 20 homolog [Mus musculus] 212772 3309 1.863333333 1.423333333 -0.388612213 Down 0.306611757 Arl14ep ADP-ribosylation factor-like 14 effector protein - GO:0044424;GO:0044424 - - "gi|148695824|gb|EDL27771.1|/1.99373e-145/RIKEN cDNA 2700007P21, isoform CRA_b, partial [Mus musculus]" 13136 2534 3.213333333 2.643333333 -0.281712281 Down 0.30658355 Cd55 "CD55 molecule, decay accelerating factor for complement" K04006|1|0.0|778|mmu:13136|decay accelerating factor - - - - 12568 2058 11.46333333 12.79666667 0.158741444 Up 0.306574147 Cdk5 cyclin-dependent kinase 5 K02090|1|6e-171|603|shr:100914143|cyclin-dependent kinase 5 [EC:2.7.11.22] GO:0031981//nuclear lumen;GO:0031252//cell leading edge;GO:0043232;GO:0044327//dendritic spine head;GO:0044444//cytoplasmic part;GO:0043025//neuronal cell body;GO:0019908//nuclear cyclin-dependent protein kinase holoenzyme complex;GO:0097060//synaptic membrane GO:0004674//protein serine/threonine kinase activity;GO:0005102//receptor binding;GO:0030546//receptor activator activity;GO:0032550 "GO:0048814//regulation of dendrite morphogenesis;GO:0043065//positive regulation of apoptotic process;GO:0009057//macromolecule catabolic process;GO:0014037//Schwann cell differentiation;GO:0048167//regulation of synaptic plasticity;GO:0007411//axon guidance;GO:0030534//adult behavior;GO:0031532//actin cytoskeleton reorganization;GO:0051899//membrane depolarization;GO:0021543//pallium development;GO:0014706//striated muscle tissue development;GO:0016567//protein ubiquitination;GO:0014070//response to organic cyclic compound;GO:0006351//transcription, DNA-templated;GO:0072657//protein localization to membrane;GO:0090313;GO:0010469//regulation of receptor activity;GO:0016477//cell migration;GO:0007600//sensory perception;GO:0001934//positive regulation of protein phosphorylation;GO:0017156//calcium ion regulated exocytosis;GO:0007612//learning;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0007270//neuron-neuron synaptic transmission;GO:0006611//protein export from nucleus;GO:0007599//hemostasis;GO:0042501//serine phosphorylation of STAT protein;GO:0006897//endocytosis;GO:0043393//regulation of protein binding;GO:0031589//cell-substrate adhesion;GO:0007050//cell cycle arrest;GO:0021953//central nervous system neuron differentiation;GO:0007632//visual behavior;GO:0070997//neuron death;GO:0006950//response to stress;GO:0070588//calcium ion transmembrane transport;GO:0030308//negative regulation of cell growth;GO:0021549//cerebellum development" gi|6680908|ref|NP_031694.1|/5.08458e-170/cyclin-dependent kinase 5 [Mus musculus] 69772 1099 0.226666667 0.49 1.112209504 Up 0.306527135 Bdh2 "3-hydroxybutyrate dehydrogenase, type 2" K00019|1|5e-134|479|rno:295458|3-hydroxybutyrate dehydrogenase [EC:1.1.1.30] GO:0044424;GO:0044424 "GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding" GO:0055080//cation homeostasis;GO:0009237//siderophore metabolic process;GO:0009062//fatty acid catabolic process;GO:0055080//cation homeostasis;GO:0009237//siderophore metabolic process;GO:0009062//fatty acid catabolic process gi|285026426|ref|NP_001165526.1|/4.22737e-134/3-hydroxybutyrate dehydrogenase type 2 isoform 1 [Mus musculus] 24061 3980 8.866666667 10.00333333 0.174017073 Up 0.306517733 Smc1a structural maintenance of chromosomes 1A K06636|1|0.0|2162|myb:102253503|structural maintenance of chromosome 1 GO:0000776//kinetochore;GO:0000228//nuclear chromosome;GO:0008278//cohesin complex GO:0032550;GO:0046983//protein dimerization activity;GO:0003774//motor activity;GO:0032403//protein complex binding GO:0006259//DNA metabolic process;GO:0009628//response to abiotic stimulus;GO:0000070//mitotic sister chromatid segregation;GO:0000377;GO:0033554//cellular response to stress;GO:0010948//negative regulation of cell cycle process;GO:0032502//developmental process;GO:0035556//intracellular signal transduction "gi|149031310|gb|EDL86308.1|/0/structural maintenance of chromosomes 1 like 1 (S. cerevisiae), isoform CRA_b [Rattus norvegicus]" 69551 3317 32.15333333 35.24 0.132245615 Up 0.306480123 2310022B05Rik RIKEN cDNA 2310022B05 gene - GO:0044424 - - gi|74199177|dbj|BAE33133.1|/1.06051e-146/unnamed protein product [Mus musculus] 320020 819.88 1.06 1.46 0.461904104 Up 0.306470721 6330415G19Rik RIKEN cDNA 6330415G19 gene K09229|1|3e-64|246|mmu:449521|KRAB and SCAN domains-containing zinc finger protein;K09230|2|4e-59|229|rno:287094|SCAN domain-containing zinc finger protein - - - - 18087 7026 4.766666667 4.063333333 -0.230317021 Down 0.306414307 Nktr natural killer tumor recognition sequence K12740|1|0.0|1832|mmu:18087|NK-tumor recognition protein - - - "gi|148677189|gb|EDL09136.1|/0/natural killer tumor recognition sequence, isoform CRA_c, partial [Mus musculus]" 19173 871 95.09333333 103.0966667 0.116581581 Up 0.306339088 Psmb5 "proteasome (prosome, macropain) subunit, beta type 5" K02737|1|6e-132|472|mmu:19173|20S proteasome subunit beta 5 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity GO:0006950//response to stress;GO:0006511//ubiquitin-dependent protein catabolic process gi|6755204|ref|NP_035316.1|/5.05977e-131/proteasome subunit beta type-5 [Mus musculus] 217779 2401 4.493333333 5.233333333 0.219944063 Up 0.306339088 Lysmd1 "LysM, putative peptidoglycan-binding, domain containing 1" - - - - gi|148669246|gb|EDL01193.1|/1.64221e-98/mCG1025408 [Mus musculus] 20742 8314.13 96.62333333 88.62666667 -0.124630771 Down 0.306339088 Sptbn1 "spectrin beta, non-erythrocytic 1" K06115|1|0.0|4372|mmu:20742|spectrin beta GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0031672//A band;GO:0032589//neuron projection membrane;GO:0030864//cortical actin cytoskeleton;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0031672//A band;GO:0032589//neuron projection membrane;GO:0030864//cortical actin cytoskeleton GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0008289//lipid binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0008289//lipid binding GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0030835//negative regulation of actin filament depolymerization;GO:0006612//protein targeting to membrane;GO:0022607//cellular component assembly;GO:0006935//chemotaxis;GO:0006606//protein import into nucleus;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0030835//negative regulation of actin filament depolymerization;GO:0006612//protein targeting to membrane;GO:0022607//cellular component assembly;GO:0006935//chemotaxis;GO:0006606//protein import into nucleus "gi|117938332|ref|NP_787030.2|/0/spectrin beta chain, non-erythrocytic 1 isoform 1 [Mus musculus]" 231440 2100 35.35333333 32.28333333 -0.1310567 Down 0.306292076 Parm1 prostate androgen-regulated mucin-like protein 1 - GO:0005768//endosome;GO:0031224//intrinsic component of membrane - GO:0051347//positive regulation of transferase activity;GO:0012501//programmed cell death gi|74148095|dbj|BAE36224.1|/7.36852e-124/unnamed protein product [Mus musculus] 257871 1803 1.74 1.31 -0.409520494 Down 0.306245064 Olfr1372-ps1 "olfactory receptor 1372, pseudogene 1" K04257|1|4e-167|562|mmu:404337|olfactory receptor GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007608//sensory perception of smell gi|43256260|gb|AAS46306.1|/0/olfactory receptor NP_TR6JSE50FPA [Mus musculus] 494504 2799 1.733333333 1.303333333 -0.411343016 Down 0.306245064 Apcdd1 adenomatosis polyposis coli down-regulated 1 - GO:0016021//integral component of membrane GO:0005515//protein binding GO:0016055//Wnt signaling pathway;GO:0008544//epidermis development;GO:0008347//glial cell migration gi|110625864|ref|NP_573500.2|/0/protein APCDD1 precursor [Mus musculus] 74091 1403 0.876666667 0.546666667 -0.681366985 Down 0.30611343 Npl N-acetylneuraminate pyruvate lyase K01639|1|5e-178|626|mmu:74091|N-acetylneuraminate lyase [EC:4.1.3.3] GO:0044424 GO:0016833//oxo-acid-lyase activity GO:0006054//N-acetylneuraminate metabolic process;GO:0044238//primary metabolic process gi|21311855|ref|NP_083025.1|/4.41458e-177/N-acetylneuraminate lyase [Mus musculus] 77866 748 3.06 2.51 -0.285844289 Down 0.30611343 E130102H24Rik RIKEN cDNA E130102H24 gene - - - - - 12399 3891 0.546666667 0.873333333 0.675870997 Up 0.30611343 Runx3 runt related transcription factor 3 K09279|1|0.0|849|mmu:12399|runt-related transcription factor 3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle "GO:0032550;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding" GO:0048666//neuron development;GO:0006366//transcription from RNA polymerase II promoter;GO:0001942//hair follicle development;GO:0008285//negative regulation of cell proliferation;GO:0021700//developmental maturation;GO:0001816//cytokine production;GO:0030030//cell projection organization;GO:0051726//regulation of cell cycle;GO:0012502//induction of programmed cell death;GO:0006935//chemotaxis;GO:0006464//cellular protein modification process gi|84579891|ref|NP_062706.2|/0/runt-related transcription factor 3 [Mus musculus] 110198 1648 31.46333333 34.50666667 0.133203594 Up 0.305981797 Akr7a5 "aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase)" K15303|1|0.0|640|mmu:110198|aflatoxin B1 aldehyde reductase GO:0044431//Golgi apparatus part "GO:0019118//phenanthrene-epoxide hydrolase activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0030647 gi|240120054|ref|NP_079613.3|/0/aflatoxin B1 aldehyde reductase member 2 [Mus musculus] 140742 2667.85 87.27666667 94.97666667 0.121977122 Up 0.30595359 Sesn1 sestrin 1 K10141|1|0.0|1066|cge:100770597|sestrin 1/3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0022402//cell cycle process;GO:0022402//cell cycle process gi|253314525|ref|NP_001156380.1|/0/sestrin-1 isoform 1 [Mus musculus] 52712 2279.47 3.03 3.633333333 0.261975935 Up 0.305934785 Zkscan6 zinc finger with KRAB and SCAN domains 6 K09229|1|0.0|1162|mmu:52712|KRAB and SCAN domains-containing zinc finger protein - - - "gi|148678461|gb|EDL10408.1|/0/zinc finger protein 535, isoform CRA_a, partial [Mus musculus]" 22346 2730 3.053333333 3.653333333 0.258828295 Up 0.305934785 Vhl von Hippel-Lindau tumor suppressor K03871|1|3e-76|289|mmu:22346|von Hippel-Lindau disease tumor supressor GO:0031981//nuclear lumen;GO:0000153//cytoplasmic ubiquitin ligase complex GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0043542//endothelial cell migration;GO:0032989;GO:0031647//regulation of protein stability;GO:0006584//catecholamine metabolic process;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0051259//protein oligomerization;GO:0030154//cell differentiation;GO:0097305//response to alcohol;GO:0032446//protein modification by small protein conjugation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0043062//extracellular structure organization gi|6678567|ref|NP_033533.1|/2.97155e-75/von Hippel-Lindau disease tumor suppressor [Mus musculus] 58804 867 3.68 4.336666667 0.23688079 Up 0.305906578 Cdc42ep5 CDC42 effector protein (Rho GTPase binding) 5 - GO:0044424;GO:0016020//membrane GO:0017048//Rho GTPase binding GO:0007265//Ras protein signal transduction;GO:0051403//stress-activated MAPK cascade;GO:0022604//regulation of cell morphogenesis;GO:0030041//actin filament polymerization;GO:0031269//pseudopodium assembly gi|568946326|ref|XP_006540312.1|/2.01812e-55/PREDICTED: cdc42 effector protein 5 isoform X2 [Mus musculus] 69259 2457 3.716666667 4.38 0.236921566 Up 0.305906578 Kctd5 potassium channel tetramerisation domain containing 5 K01011|1|1e-62|244|fch:102052071|thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2];K15074|3|3e-09|66.6|hmg:100213269|BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding GO:0051259//protein oligomerization gi|37359818|dbj|BAC97887.1|/3.62195e-117/mKIAA4250 protein [Mus musculus] 380863 1183 3.576666667 4.236666667 0.244313954 Up 0.305906578 Tmem171 transmembrane protein 171 - GO:0031224//intrinsic component of membrane - - "gi|148668527|gb|EDL00846.1|/8.24681e-171/gene model 905, (NCBI), partial [Mus musculus]" 13640 5225.41 2.146666667 2.67 0.314741554 Up 0.305859566 Efna5 ephrin A5 K05462|1|7e-126|455|mmu:13640|ephrin-A GO:0046658//anchored component of plasma membrane;GO:0046658//anchored component of plasma membrane "GO:0005102//receptor binding;GO:0005102//receptor binding;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0001952//regulation of cell-matrix adhesion;GO:0007411//axon guidance;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0001934//positive regulation of protein phosphorylation;GO:0000226//microtubule cytoskeleton organization;GO:0007417//central nervous system development;GO:0030036//actin cytoskeleton organization;GO:0050796//regulation of insulin secretion;GO:0012501//programmed cell death;GO:0001952//regulation of cell-matrix adhesion;GO:0007411//axon guidance;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0001934//positive regulation of protein phosphorylation;GO:0000226//microtubule cytoskeleton organization;GO:0007417//central nervous system development;GO:0030036//actin cytoskeleton organization;GO:0050796//regulation of insulin secretion;GO:0012501//programmed cell death gi|46560570|ref|NP_997537.1|/6.49749e-125/ephrin-A5 isoform 1 precursor [Mus musculus] 224619 2707.91 19.39 21.39333333 0.141848485 Up 0.305831359 Traf7 TNF receptor-associated factor 7 K10646|1|0.0|1207|cge:100756531|E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27] GO:0043227//membrane-bounded organelle;GO:0016020//membrane;GO:0043227//membrane-bounded organelle;GO:0016020//membrane;GO:0043227//membrane-bounded organelle;GO:0016020//membrane GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0032147//activation of protein kinase activity;GO:0006915//apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0000165//MAPK cascade;GO:0032147//activation of protein kinase activity;GO:0006915//apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0000165//MAPK cascade;GO:0032147//activation of protein kinase activity;GO:0006915//apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0000165//MAPK cascade gi|285403618|ref|NP_001165584.1|/0/E3 ubiquitin-protein ligase TRAF7 isoform 1 [Mus musculus] 105148 4396 22.13666667 20.13666667 -0.136613112 Down 0.305831359 Iars isoleucine-tRNA synthetase K01870|1|0.0|2492|mmu:105148|isoleucyl-tRNA synthetase [EC:6.1.1.5] GO:0044424 GO:0032550;GO:0052689//carboxylic ester hydrolase activity;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation "gi|254553372|ref|NP_742012.2|/0/isoleucine--tRNA ligase, cytoplasmic [Mus musculus]" 20775 2748 0.233333333 0.496666667 1.089885504 Up 0.305793749 Sqle squalene epoxidase K00511|1|0.0|1017|mmu:20775|squalene monooxygenase [EC:1.14.14.17] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0003824//catalytic activity;GO:0000166//nucleotide binding GO:0044237//cellular metabolic process;GO:0016125//sterol metabolic process;GO:0042221//response to chemical gi|6678127|ref|NP_033296.1|/0/squalene monooxygenase [Mus musculus] 329002 9473 2.16 1.693333333 -0.351165316 Down 0.305727933 Zfp236 zinc finger protein 236 K09228|1|6e-139|499|gja:107115679|KRAB domain-containing zinc finger protein - - - gi|254939702|ref|NP_808500.2|/0/zinc finger protein 236 [Mus musculus] 17463 1616 83.50666667 90.99666667 0.12392232 Up 0.30571853 Psmd7 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 7" K03038|1|2e-144|514|cge:100761962|26S proteasome regulatory subunit N8 GO:0031981//nuclear lumen;GO:0022624//proteasome accessory complex;GO:0044444//cytoplasmic part GO:0005488//binding "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0006915//apoptotic process;GO:0044764;GO:0051320;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|664719219|ref|XP_008516632.1|/1.98757e-147/PREDICTED: 26S proteasome non-ATPase regulatory subunit 7 [Equus przewalskii] 22419 2247.03 0.773333333 1.136666667 0.555646934 Up 0.305690323 Wnt5b "wingless-type MMTV integration site family, member 5B" "K00444|1|0.0|744|cge:100753017|wingless-type MMTV integration site family, member 5" GO:0031012//extracellular matrix;GO:0005576//extracellular region;GO:0044464;GO:0031012//extracellular matrix;GO:0005576//extracellular region;GO:0044464;GO:0031012//extracellular matrix;GO:0005576//extracellular region;GO:0044464 GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0016477//cell migration;GO:0009611//response to wounding;GO:0030178//negative regulation of Wnt signaling pathway;GO:0044767//single-organism developmental process;GO:0048513//animal organ development;GO:0009653//anatomical structure morphogenesis;GO:0045444//fat cell differentiation;GO:0016477//cell migration;GO:0009611//response to wounding;GO:0030178//negative regulation of Wnt signaling pathway;GO:0044767//single-organism developmental process;GO:0048513//animal organ development;GO:0009653//anatomical structure morphogenesis;GO:0045444//fat cell differentiation;GO:0016477//cell migration;GO:0009611//response to wounding;GO:0030178//negative regulation of Wnt signaling pathway;GO:0044767//single-organism developmental process;GO:0048513//animal organ development;GO:0009653//anatomical structure morphogenesis;GO:0045444//fat cell differentiation gi|202406|gb|AAA40568.1|/0/Wnt-5b [Mus musculus] 231004 2610 2.296666667 2.83 0.301260571 Up 0.305680921 Samd11 sterile alpha motif domain containing 11 K11456|1|6e-07|59.3|hst:105190243|polyhomeotic-like protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0019904//protein domain specific binding - gi|160333442|ref|NP_001103986.1|/0/sterile alpha motif domain-containing protein 11 [Mus musculus] 114615 4971 2.346666667 2.88 0.295455884 Up 0.305680921 Elac1 elaC ribonuclease Z 1 K00784|1|0.0|711|mmu:114615|ribonuclease Z [EC:3.1.26.11] - - - - 628308 4664 14.64333333 16.19333333 0.145155991 Up 0.305577494 Gm14420 zinc finger protein 970 K09228|1|0.0|916|cge:100770581|KRAB domain-containing zinc finger protein - - - gi|294774589|ref|NP_001171039.1|/0/KRAB box and zinc finger C2H2 type domain containing protein-like [Mus musculus] 67603 2814 12.18333333 10.88 -0.163230349 Down 0.305539885 Dusp6 dual specificity phosphatase 6 K04459|1|0.0|667|xla:100505429|dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] - - - gi|13399314|ref|NP_080544.1|/0/dual specificity protein phosphatase 6 [Mus musculus] 27049 5140 5.9 5.11 -0.207391663 Down 0.305530483 Etv3 ets variant 3 K09433|1|0.0|1000|mmu:27049|ETS translocation variant 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter gi|134031941|ref|NP_001076787.1|/0/ETS translocation variant 3 [Mus musculus] 240354 5008 2.073333333 1.616666667 -0.358929833 Down 0.305530483 Malt1 MALT1 paracaspase K07369|1|0.0|1546|mmu:240354|mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-] - - - - 320720 2877 7.336666667 6.413333333 -0.194050346 Down 0.305502275 Fastkd1 FAST kinase domains 1 K18190|1|6e-15|85.9|ccw:104693798|FAST kinase domain-containing protein 2 GO:0043231//intracellular membrane-bounded organelle GO:0016301//kinase activity GO:0006464//cellular protein modification process;GO:0015980//energy derivation by oxidation of organic compounds gi|56710329|ref|NP_796218.2|/0/FAST kinase domain-containing protein 1 [Mus musculus] 80281 4838 7.33 6.406666667 -0.194239268 Down 0.305502275 Cttnbp2nl CTTNBP2 N-terminal like K11515|1|2e-12|78.6|amj:102562978|inner centromere protein;K10352|3|3e-11|74.3|ocu:100009001|myosin heavy chain GO:0005856//cytoskeleton;GO:0005856//cytoskeleton;GO:0005856//cytoskeleton GO:0005488//binding - gi|37360382|dbj|BAC98169.1|/0/mKIAA1433 protein [Mus musculus] 18830 1806 32.56666667 35.52666667 0.125506271 Up 0.305408252 Pltp phospholipid transfer protein K08761|1|0.0|867|mmu:18830|phospholipid transfer protein - GO:0005488//binding GO:0048870//cell motility;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0018130 gi|6755112|ref|NP_035255.1|/0/phospholipid transfer protein precursor [Mus musculus] 20607 3928 0.95 0.613333333 -0.631256153 Down 0.305389447 Sstr3 somatostatin receptor 3 K04219|1|1e-164|583|mmu:20607|somatostatin receptor 3 GO:0016021//integral component of membrane;GO:0072372//primary cilium;GO:0031090//organelle membrane GO:0005488//binding GO:0022037//metencephalon development;GO:0051384//response to glucocorticoid;GO:0009755//hormone-mediated signaling pathway;GO:0048232//male gamete generation;GO:0032355//response to estradiol;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0006950//response to stress gi|84370258|ref|NP_033244.2|/8.81244e-164/somatostatin receptor type 3 [Mus musculus] 240518 1937 0.61 0.946666667 0.634047281 Up 0.305389447 Peli3 pellino 3 K11964|1|0.0|914|mmu:240518|pellino [EC:2.3.2.27] - - - - 230661 3032 1.326666667 1.753333333 0.402294369 Up 0.305304825 Tesk2 testis-specific kinase 2 K08842|1|0.0|1117|mmu:230661|testis-specific kinase 2 [EC:2.7.12.1] GO:0031981//nuclear lumen GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity GO:0012501//programmed cell death;GO:0007010//cytoskeleton organization;GO:0007044//cell-substrate junction assembly;GO:0006464//cellular protein modification process;GO:0048232//male gamete generation;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction gi|755508075|ref|XP_011238794.1|/0/PREDICTED: dual specificity testis-specific protein kinase 2 isoform X1 [Mus musculus] 207565 4903 2.53 2.026666667 -0.320028562 Down 0.305304825 Camkk2 "calcium/calmodulin-dependent protein kinase kinase 2, beta" K07359|1|0.0|998|mmu:207565|calcium/calmodulin-dependent protein kinase kinase [EC:2.7.11.17] GO:0044424;GO:0044424 GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0019887//protein kinase regulator activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0019887//protein kinase regulator activity GO:0045860//positive regulation of protein kinase activity;GO:0045860//positive regulation of protein kinase activity gi|26327287|dbj|BAC27387.1|/0/unnamed protein product [Mus musculus] 320295 1447 0.923333333 1.303333333 0.497282631 Up 0.305295423 C920006O11Rik RIKEN cDNA C920006O11 gene K00799|1|8e-10|67.8|hgl:101714626|glutathione S-transferase [EC:2.5.1.18] - "GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups" GO:0006790//sulfur compound metabolic process;GO:0044710 "gi|148694427|gb|EDL26374.1|/6.30488e-34/mCG1035341, isoform CRA_a [Mus musculus]" 73558 708 0.15 0.39 1.378511623 Up 0.305276618 1700110K17Rik RIKEN cDNA 1700110K17 gene - - - - - 94353 923 3.403333333 2.82 -0.271253298 Down 0.305173192 Hmgn3 high mobility group nucleosomal binding domain 3 K11301|1|8e-28|124|ecb:100069315|high-mobility group nucleosome-binding domain-containing protein 3 GO:0031981//nuclear lumen;GO:0043232 GO:0008134//transcription factor binding;GO:0031490//chromatin DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0050796//regulation of insulin secretion;GO:0044093;GO:0006325//chromatin organization gi|21313298|ref|NP_080398.1|/1.61447e-37/high mobility group nucleosome-binding domain-containing protein 3 isoform Hmgn3a [Mus musculus] 226089 6282 3.36 2.783333333 -0.271647536 Down 0.305173192 Ric1 RAB6A GEF complex partner 1 K20476|1|0.0|2709|mmu:226089|RAB6A-GEF complex partner protein 1 GO:0031224//intrinsic component of membrane - - gi|124486767|ref|NP_001074788.1|/0/RAB6A-GEF complex partner protein 1 [Mus musculus] 80294 2219 31.88666667 34.79666667 0.12599582 Up 0.305032156 Pofut2 protein O-fucosyltransferase 2 K03691|1|0.0|867|mmu:80294|peptide-O-fucosyltransferase [EC:2.4.1.221] GO:0043231//intracellular membrane-bounded organelle GO:0008417//fucosyltransferase activity GO:0001837//epithelial to mesenchymal transition;GO:0019318//hexose metabolic process;GO:0046903//secretion;GO:0010467//gene expression;GO:0006493//protein O-linked glycosylation;GO:0001704//formation of primary germ layer gi|19525731|ref|NP_084538.2|/0/GDP-fucose protein O-fucosyltransferase 2 precursor [Mus musculus] 72085 1862.82 30.22333333 33.13333333 0.132620567 Up 0.305032156 Osgepl1 O-sialoglycoprotein endopeptidase-like 1 K01409|1|0.0|798|mmu:72085|N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0006399//tRNA metabolic process;GO:0006399//tRNA metabolic process;GO:0006399//tRNA metabolic process "gi|148667576|gb|EDK99992.1|/0/O-sialoglycoprotein endopeptidase-like 1, isoform CRA_b, partial [Mus musculus]" 57377 2798 4 4.686666667 0.228562189 Up 0.305022754 Mogs mannosyl-oligosaccharide glucosidase K01228|1|0.0|1540|mmu:57377|mannosyl-oligosaccharide glucosidase [EC:3.2.1.106] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0015926//glucosidase activity GO:0044723 gi|31981106|ref|NP_065644.2|/0/mannosyl-oligosaccharide glucosidase [Mus musculus] 329504 3407 4.056666667 4.746666667 0.226619978 Up 0.305022754 Lcmt2 leucine carboxyl methyltransferase 2 K15451|1|0.0|1247|mmu:329504|tRNA wybutosine-synthesizing protein 4 [EC:2.1.1.290 2.3.1.231] - - - - 56418 2491 31.12666667 34.01333333 0.12794931 Up 0.304919328 Ykt6 YKT6 v-SNARE homolog (S. cerevisiae) K08516|1|4e-96|355|mmu:56418|synaptobrevin homolog YKT6 - - - - 73681 2359 1.156666667 1.563333333 0.43465226 Up 0.304750085 Trmt11 tRNA methyltransferase 11 K15430|1|0.0|950|mmu:73681|tRNA (guanine10-N2)-methyltransferase [EC:2.1.1.214] - GO:0016741;GO:0097159//organic cyclic compound binding GO:0006399//tRNA metabolic process "gi|148672901|gb|EDL04848.1|/0/RIKEN cDNA 2410075D05, isoform CRA_b, partial [Mus musculus]" 104027 4546.1 84.35666667 77.67 -0.119144623 Down 0.304627854 Synpo synaptopodin K05740|1|1e-05|56.2|chx:102183869|diaphanous 1 GO:0043296//apical junction complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0043025//neuronal cell body;GO:0032432//actin filament bundle GO:0008092//cytoskeletal protein binding GO:0032231//regulation of actin filament bundle assembly gi|74182827|dbj|BAE34731.1|/0/unnamed protein product [Mus musculus] 12487 4317 0.84 1.206666667 0.522565964 Up 0.304599646 Cd28 CD28 antigen K06470|1|5e-126|455|mmu:12487|CD28 antigen GO:0009986//cell surface;GO:0031224//intrinsic component of membrane "GO:0038023//signaling receptor activity;GO:0030674//protein binding, bridging;GO:0042802//identical protein binding;GO:0019899//enzyme binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0045830//positive regulation of isotype switching;GO:0042102//positive regulation of T cell proliferation;GO:0002437//inflammatory response to antigenic stimulus;GO:0042094//interleukin-2 biosynthetic process;GO:0031294//lymphocyte costimulation;GO:0007067//mitotic nuclear division;GO:0007165//signal transduction;GO:0043383//negative T cell selection gi|161484597|ref|NP_031668.3|/4.02415e-125/T-cell-specific surface glycoprotein CD28 precursor [Mus musculus] 58809 1543.29 30.01 32.85 0.130450052 Up 0.304477415 Rnase4 "ribonuclease, RNase A family 4" K16632|1|4e-74|281|mmu:58809|ribonuclease 4 [EC:3.1.27.-] - "GO:0016892//endoribonuclease activity, producing 3'-phosphomonoesters;GO:0097159//organic cyclic compound binding;GO:0016892//endoribonuclease activity, producing 3'-phosphomonoesters;GO:0097159//organic cyclic compound binding" - gi|47679082|ref|NP_067447.2|/3.82636e-73/ribonuclease 4 precursor [Mus musculus] 224019 1463 0.506666667 0.83 0.712074419 Up 0.304458611 Tmem191c transmembrane protein 191C - GO:0016020//membrane - - gi|224809221|ref|NP_803424.2|/3.65797e-113/transmembrane protein 191C [Mus musculus] 19727 3660.21 9.063333333 10.17 0.166206029 Up 0.304449208 Rfxank regulatory factor X-associated ankyrin-containing protein K08062|1|5e-144|514|mmu:19727|regulatory factor X-associated ankyrin-containing protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0019899//enzyme binding;GO:0019899//enzyme binding GO:0007264//small GTPase mediated signal transduction;GO:0006366//transcription from RNA polymerase II promoter;GO:0007264//small GTPase mediated signal transduction;GO:0006366//transcription from RNA polymerase II promoter "gi|148696839|gb|EDL28786.1|/6.05082e-151/regulatory factor X-associated ankyrin-containing protein, isoform CRA_b, partial [Mus musculus]" 218341 2252.57 2.43 2.966666667 0.287886522 Up 0.304449208 Rfesd Rieske (Fe-S) domain containing - - GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding;GO:0003824//catalytic activity GO:0044710;GO:0044710;GO:0044710 gi|197100626|ref|NP_849247.3|/1.56918e-87/Rieske domain-containing protein [Mus musculus] 118445 2652 2.456666667 2.993333333 0.285050826 Up 0.304449208 Klf16 Kruppel-like factor 16 K09208|1|3e-81|306|mmu:118445|krueppel-like factor 9/13/14/16 - GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter gi|144922690|ref|NP_510962.2|/2.27783e-80/Krueppel-like factor 16 [Mus musculus] 69215 912 2.966666667 2.426666667 -0.289866886 Down 0.304449208 Sat2 spermidine/spermine N1-acetyl transferase 2 K00657|1|7e-94|345|mmu:69215|diamine N-acetyltransferase [EC:2.3.1.57] GO:0044424 GO:0008080//N-acetyltransferase activity GO:0006598//polyamine catabolic process gi|124249210|ref|NP_081267.1|/5.89072e-93/diamine acetyltransferase 2 [Mus musculus] 59020 2389 1.446666667 1.883333333 0.380555825 Up 0.304449208 Pdzk1 PDZ domain containing 1 K13365|1|6e-37|158|pps:100976426|Na(+)/H(+) exchange regulatory cofactor NHE-RF1 GO:0005903//brush border;GO:0044459;GO:0005902//microvillus;GO:0044424;GO:0005903//brush border;GO:0044459;GO:0005902//microvillus;GO:0044424 GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding GO:0090150//establishment of protein localization to membrane;GO:0015918//sterol transport;GO:0034220//ion transmembrane transport;GO:0006812//cation transport;GO:0090150//establishment of protein localization to membrane;GO:0015918//sterol transport;GO:0034220//ion transmembrane transport;GO:0006812//cation transport "gi|148706974|gb|EDL38921.1|/0/PDZ domain containing 1, isoform CRA_b, partial [Mus musculus]" 13618 3850.85 5.803333333 5.026666667 -0.207279774 Down 0.304439806 Ednrb endothelin receptor type B K04198|1|0.0|869|mmu:13618|endothelin receptor type B GO:0016021//integral component of membrane;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0005635//nuclear envelope GO:0031701//angiotensin receptor binding;GO:0008528//G-protein coupled peptide receptor activity;GO:0042277//peptide binding;GO:0031701//angiotensin receptor binding;GO:0008528//G-protein coupled peptide receptor activity;GO:0042277//peptide binding;GO:0031701//angiotensin receptor binding;GO:0008528//G-protein coupled peptide receptor activity;GO:0042277//peptide binding GO:0033555//multicellular organismal response to stress;GO:0001932//regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0042044//fluid transport;GO:0007494//midgut development;GO:0001660//fever generation;GO:0035809;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0050931//pigment cell differentiation;GO:0001667//ameboidal-type cell migration;GO:0019233//sensory perception of pain;GO:0043084//penile erection;GO:0014821;GO:0035813//regulation of renal sodium excretion;GO:0030595//leukocyte chemotaxis;GO:0042127//regulation of cell proliferation;GO:0050880//regulation of blood vessel size;GO:0014041//regulation of neuron maturation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0048483//autonomic nervous system development;GO:0032496//response to lipopolysaccharide;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0033555//multicellular organismal response to stress;GO:0001932//regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0042044//fluid transport;GO:0007494//midgut development;GO:0001660//fever generation;GO:0035809;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0031324//negative regulation of cellular metabolic process;GO:0050931//pigment cell differentiation;GO:0001667//ameboidal-type cell migration;GO:0019233//sensory perception of pain;GO:0043084//penile erection;GO:0014821;GO:0035813//regulation of renal sodium excretion;GO:0030595//leukocyte chemotaxis;GO:0042127//regulation of cell proliferation;GO:0050880//regulation of blood vessel size;GO:0014041//regulation of neuron maturation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0048483//autonomic nervous system development;GO:0032496//response to lipopolysaccharide;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0033555//multicellular organismal response to stress;GO:0001932//regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0042044//fluid transport;GO:0007494//midgut development;GO:0001660//fever generation;GO:0035809;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0050931//pigment cell differentiation;GO:0001667//ameboidal-type cell migration;GO:0019233//sensory perception of pain;GO:0043084//penile erection;GO:0014821;GO:0035813//regulation of renal sodium excretion;GO:0030595//leukocyte chemotaxis;GO:0042127//regulation of cell proliferation;GO:0050880//regulation of blood vessel size;GO:0014041//regulation of neuron maturation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0048483//autonomic nervous system development;GO:0032496//response to lipopolysaccharide;GO:0051480//regulation of cytosolic calcium ion concentration "gi|148668175|gb|EDL00505.1|/0/endothelin receptor type B, isoform CRA_b, partial [Mus musculus]" 241490 1904 5.033333333 5.81 0.20702402 Up 0.304439806 Rbm45 RNA binding motif protein 45 K13207|1|1e-16|90.9|asn:102386222|CUG-BP- and ETR3-like factor GO:0043231//intracellular membrane-bounded organelle GO:0036094//small molecule binding;GO:0003676//nucleic acid binding GO:0048731//system development;GO:0048869//cellular developmental process gi|23510273|ref|NP_700454.1|/0/RNA-binding protein 45 [Mus musculus] 18439 4858.55 1.026666667 1.42 0.46792308 Up 0.304383392 P2rx7 "purinergic receptor P2X, ligand-gated ion channel, 7" K05220|1|0.0|1090|mmu:18439|P2X purinoceptor 7 GO:0033267;GO:0031229;GO:0045202//synapse;GO:0030054//cell junction;GO:0009986//cell surface;GO:0032991//macromolecular complex;GO:0044297//cell body;GO:0016021//integral component of membrane;GO:0033267;GO:0031229;GO:0045202//synapse;GO:0030054//cell junction;GO:0009986//cell surface;GO:0032991//macromolecular complex;GO:0044297//cell body;GO:0016021//integral component of membrane;GO:0033267;GO:0031229;GO:0045202//synapse;GO:0030054//cell junction;GO:0009986//cell surface;GO:0032991//macromolecular complex;GO:0044297//cell body;GO:0016021//integral component of membrane;GO:0033267;GO:0031229;GO:0045202//synapse;GO:0030054//cell junction;GO:0009986//cell surface;GO:0032991//macromolecular complex;GO:0044297//cell body;GO:0016021//integral component of membrane GO:0008289//lipid binding;GO:0030295//protein kinase activator activity;GO:0046914//transition metal ion binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0016502;GO:0005515//protein binding;GO:0032550;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0030295//protein kinase activator activity;GO:0046914//transition metal ion binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0016502;GO:0032550;GO:0008289//lipid binding;GO:0030295//protein kinase activator activity;GO:0046914//transition metal ion binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0016502;GO:0005515//protein binding;GO:0032550;GO:0008289//lipid binding;GO:0030295//protein kinase activator activity;GO:0046914//transition metal ion binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0016502;GO:0005515//protein binding;GO:0032550 GO:0006915//apoptotic process;GO:0033619//membrane protein proteolysis;GO:0007600//sensory perception;GO:0001894//tissue homeostasis;GO:0030163//protein catabolic process;GO:0042742//defense response to bacterium;GO:0046683//response to organophosphorus;GO:0009628//response to abiotic stimulus;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0002237//response to molecule of bacterial origin;GO:0006814//sodium ion transport;GO:0006461//protein complex assembly;GO:0048522;GO:0001501//skeletal system development;GO:0030282//bone mineralization;GO:0000165//MAPK cascade;GO:0014047//glutamate secretion;GO:0015914//phospholipid transport;GO:0032731//positive regulation of interleukin-1 beta production;GO:0042110//T cell activation;GO:0032305//positive regulation of icosanoid secretion;GO:0007010//cytoskeleton organization;GO:0032730//positive regulation of interleukin-1 alpha production;GO:0019835//cytolysis;GO:0014051//gamma-aminobutyric acid secretion;GO:0044259//multicellular organismal macromolecule metabolic process;GO:0051283//negative regulation of sequestering of calcium ion;GO:0032846;GO:0032845;GO:0001508//action potential;GO:0006862//nucleotide transport;GO:0009605//response to external stimulus;GO:0050663//cytokine secretion;GO:0001932//regulation of protein phosphorylation;GO:0010038//response to metal ion;GO:0032989;GO:0006887//exocytosis;GO:0002260//lymphocyte homeostasis;GO:0051604//protein maturation;GO:0006909//phagocytosis;GO:0006672//ceramide metabolic process;GO:0044093;GO:0010522//regulation of calcium ion transport into cytosol;GO:0030031//cell projection assembly;GO:0035587//purinergic receptor signaling pathway;GO:0006915//apoptotic process;GO:0033619//membrane protein proteolysis;GO:0007600//sensory perception;GO:0001894//tissue homeostasis;GO:0030163//protein catabolic process;GO:0042742//defense response to bacterium;GO:0046683//response to organophosphorus;GO:0009628//response to abiotic stimulus;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0002237//response to molecule of bacterial origin;GO:0006814//sodium ion transport;GO:0006461//protein complex assembly;GO:0048522;GO:0001501//skeletal system development;GO:0030282//bone mineralization;GO:0000165//MAPK cascade;GO:0014047//glutamate secretion;GO:0015914//phospholipid transport;GO:0032731//positive regulation of interleukin-1 beta production;GO:0042110//T cell activation;GO:0032305//positive regulation of icosanoid secretion;GO:0007010//cytoskeleton organization;GO:0032730//positive regulation of interleukin-1 alpha production;GO:0019835//cytolysis;GO:0014051//gamma-aminobutyric acid secretion;GO:0044259//multicellular organismal macromolecule metabolic process;GO:0051283//negative regulation of sequestering of calcium ion;GO:0032846;GO:0032845;GO:0001508//action potential;GO:0006862//nucleotide transport;GO:0009605//response to external stimulus;GO:0050663//cytokine secretion;GO:0001932//regulation of protein phosphorylation;GO:0010038//response to metal ion;GO:0032989;GO:0006887//exocytosis;GO:0002260//lymphocyte homeostasis;GO:0051604//protein maturation;GO:0006909//phagocytosis;GO:0006672//ceramide metabolic process;GO:0044093;GO:0010522//regulation of calcium ion transport into cytosol;GO:0030522//intracellular receptor signaling pathway;GO:0030031//cell projection assembly;GO:0035587//purinergic receptor signaling pathway;GO:0006915//apoptotic process;GO:0033619//membrane protein proteolysis;GO:0007600//sensory perception;GO:0001894//tissue homeostasis;GO:0030163//protein catabolic process;GO:0042742//defense response to bacterium;GO:0046683//response to organophosphorus;GO:0009628//response to abiotic stimulus;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0002237//response to molecule of bacterial origin;GO:0006814//sodium ion transport;GO:0006461//protein complex assembly;GO:0048522;GO:0001501//skeletal system development;GO:0030282//bone mineralization;GO:0000165//MAPK cascade;GO:0014047//glutamate secretion;GO:0015914//phospholipid transport;GO:0032731//positive regulation of interleukin-1 beta production;GO:0042110//T cell activation;GO:0032305//positive regulation of icosanoid secretion;GO:0007010//cytoskeleton organization;GO:0032730//positive regulation of interleukin-1 alpha production;GO:0019835//cytolysis;GO:0014051//gamma-aminobutyric acid secretion;GO:0044259//multicellular organismal macromolecule metabolic process;GO:0051283//negative regulation of sequestering of calcium ion;GO:0032846;GO:0032845;GO:0001508//action potential;GO:0006862//nucleotide transport;GO:0009605//response to external stimulus;GO:0050663//cytokine secretion;GO:0001932//regulation of protein phosphorylation;GO:0010038//response to metal ion;GO:0032989;GO:0006887//exocytosis;GO:0002260//lymphocyte homeostasis;GO:0051604//protein maturation;GO:0006909//phagocytosis;GO:0006672//ceramide metabolic process;GO:0044093;GO:0010522//regulation of calcium ion transport into cytosol;GO:0030031//cell projection assembly;GO:0035587//purinergic receptor signaling pathway;GO:0006915//apoptotic process;GO:0033619//membrane protein proteolysis;GO:0007600//sensory perception;GO:0001894//tissue homeostasis;GO:0030163//protein catabolic process;GO:0042742//defense response to bacterium;GO:0046683//response to organophosphorus;GO:0009628//response to abiotic stimulus;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0002237//response to molecule of bacterial origin;GO:0006814//sodium ion transport;GO:0006461//protein complex assembly;GO:0048522;GO:0001501//skeletal system development;GO:0030282//bone mineralization;GO:0000165//MAPK cascade;GO:0014047//glutamate secretion;GO:0015914//phospholipid transport;GO:0032731//positive regulation of interleukin-1 beta production;GO:0042110//T cell activation;GO:0032305//positive regulation of icosanoid secretion;GO:0007010//cytoskeleton organization;GO:0032730//positive regulation of interleukin-1 alpha production;GO:0019835//cytolysis;GO:0014051//gamma-aminobutyric acid secretion;GO:0044259//multicellular organismal macromolecule metabolic process;GO:0051283//negative regulation of sequestering of calcium ion;GO:0032846;GO:0032845;GO:0001508//action potential;GO:0006862//nucleotide transport;GO:0009605//response to external stimulus;GO:0050663//cytokine secretion;GO:0001932//regulation of protein phosphorylation;GO:0010038//response to metal ion;GO:0032989;GO:0006887//exocytosis;GO:0002260//lymphocyte homeostasis;GO:0051604//protein maturation;GO:0006909//phagocytosis;GO:0006672//ceramide metabolic process;GO:0044093;GO:0010522//regulation of calcium ion transport into cytosol;GO:0030031//cell projection assembly;GO:0035587//purinergic receptor signaling pathway gi|23504405|emb|CAD33539.1|/0/P2X purinoceptor 7 [Mus musculus] 633057 1624 3.846666667 3.23 -0.252074653 Down 0.304373989 Gm7102 predicted gene 7102 - GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle - GO:0000087//mitotic M phase gi|294661837|ref|NP_001170984.1|/1.19866e-67/TTD non-photosensitive 1-like protein [Mus musculus] 66083 1669 7.616666667 8.613333333 0.177411905 Up 0.304345782 Setd6 SET domain containing 6 K05302|1|0.0|833|mmu:66083|N-lysine methyltransferase SETD6 [EC:2.1.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0008134//transcription factor binding;GO:0008276//protein methyltransferase activity GO:0006954//inflammatory response;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0018022//peptidyl-lysine methylation gi|78097104|ref|NP_001030295.1|/0/N-lysine methyltransferase SETD6 [Mus musculus] 272027 3726 73.56666667 80.07 0.122209582 Up 0.304279965 Tstd2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 - - - - gi|144922728|ref|NP_766621.3|/0/thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 [Mus musculus] 269881 3693 10.58666667 11.85333333 0.163044412 Up 0.304251758 Map3k10 mitogen-activated protein kinase kinase kinase 10 K04418|1|0.0|1569|mmu:269881|mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25] GO:0044424 GO:0032550;GO:0003712//transcription cofactor activity;GO:0042802//identical protein binding;GO:0004709//MAP kinase kinase kinase activity;GO:0008134//transcription factor binding "GO:0006351//transcription, DNA-templated;GO:0007166//cell surface receptor signaling pathway;GO:0000186//activation of MAPKK activity;GO:0007254//JNK cascade;GO:0044092//negative regulation of molecular function;GO:0012502//induction of programmed cell death;GO:0000187//activation of MAPK activity" gi|594542533|ref|NP_001277457.1|/0/mitogen-activated protein kinase kinase kinase 10 [Mus musculus] 233490 4403.58 3.613333333 3.026666667 -0.255600554 Down 0.304214149 Crebzf CREB/ATF bZIP transcription factor - - - - - 217151 1616 0.4 0.7 0.807354922 Up 0.304120125 Arl5c ADP-ribosylation factor-like 5C K07960|1|5e-98|360|mmu:217151|ADP-ribosylation factor-like protein 12 GO:0044464 GO:0032550 GO:0035556//intracellular signal transduction "gi|148684160|gb|EDL16107.1|/4.20241e-97/ADP-ribosylation factor-like 5C, isoform CRA_a, partial [Mus musculus]" 71151 3569 0.696666667 0.396666667 -0.812541369 Down 0.304120125 Eri2 exoribonuclease 2 K18417|1|0.0|1359|mmu:71151|ERI1 exoribonuclease 2 [EC:3.1.-.-] GO:0044464 GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0004518//nuclease activity - gi|61098180|ref|NP_081974.3|/0/ERI1 exoribonuclease 2 [Mus musculus] 108737 4647 15.44666667 13.94 -0.148064982 Down 0.304110722 Oxsr1 oxidative-stress responsive 1 K08835|1|0.0|935|mmu:108737|serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1] GO:0044424;GO:0044424 GO:0046872//metal ion binding;GO:0004672//protein kinase activity;GO:0032550;GO:0046872//metal ion binding;GO:0004672//protein kinase activity;GO:0032550 GO:0035556//intracellular signal transduction;GO:0006796//phosphate-containing compound metabolic process;GO:0006950//response to stress;GO:0006464//cellular protein modification process;GO:0035556//intracellular signal transduction;GO:0006796//phosphate-containing compound metabolic process;GO:0006950//response to stress;GO:0006464//cellular protein modification process "gi|148677282|gb|EDL09229.1|/0/mCG20975, isoform CRA_c, partial [Mus musculus]" 667277 2166 0.286666667 0.57 0.99158776 Up 0.30410132 C1rb "complement component 1, r subcomponent B" "K01330|1|0.0|1446|mmu:50909|complement component 1, r subcomponent [EC:3.4.21.41]" - GO:0046872//metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0006952//defense response;GO:0002455//humoral immune response mediated by circulating immunoglobulin gi|164518919|ref|NP_001106827.1|/0/complement C1r-B subcomponent precursor [Mus musculus] 53332 4652 5.003333333 4.286666667 -0.223033334 Down 0.304091918 Mtmr1 myotubularin related protein 1 K18081|1|0.0|1251|ocu:100354324|myotubularin-related protein 1/2 [EC:3.1.3.64 3.1.3.95] GO:0016020//membrane;GO:0044424 GO:0004721//phosphoprotein phosphatase activity GO:0006796//phosphate-containing compound metabolic process gi|8393794|ref|NP_058681.1|/0/myotubularin-related protein 1 isoform A [Mus musculus] 97387 3557.15 28.58333333 31.37 0.134211359 Up 0.304082515 Strn4 "striatin, calmodulin binding protein 4" K17608|1|0.0|1157|mmu:97387|striatin 1/3/4 GO:0044424;GO:0008287//protein serine/threonine phosphatase complex;GO:0030425//dendrite GO:0019903//protein phosphatase binding;GO:0019904//protein domain specific binding - gi|89886486|ref|NP_001034967.1|/0/striatin-4 isoform 2 [Mus musculus] 16816 1370 0.943333333 1.323333333 0.488336954 Up 0.304026101 Lcat lecithin cholesterol acyltransferase K00650|1|0.0|885|mmu:16816|lecithin-cholesterol acyltransferase [EC:2.3.1.43] GO:0034358//plasma lipoprotein particle GO:0004620//phospholipase activity;GO:0008374//O-acyltransferase activity;GO:0034185//apolipoprotein binding GO:0055092//sterol homeostasis;GO:0010038//response to metal ion;GO:0034645//cellular macromolecule biosynthetic process;GO:0034434//sterol esterification;GO:0034370//triglyceride-rich lipoprotein particle remodeling;GO:0044087;GO:0030301//cholesterol transport;GO:0019538//protein metabolic process;GO:0016125//sterol metabolic process;GO:0046165;GO:0031960//response to corticosteroid;GO:0006796//phosphate-containing compound metabolic process gi|12836459|dbj|BAB23665.1|/0/unnamed protein product [Mus musculus] 52683 3323.33 28.76666667 31.55 0.133241947 Up 0.304016699 Ncaph2 "non-SMC condensin II complex, subunit H2" K11490|1|0.0|1053|mmu:52683|condensin-2 complex subunit H2 - - - - 211484 2051 0.35 0.643333333 0.87821152 Up 0.303875663 Tsga10 testis specific 10 K19983|1|0.0|642|amj:102576116|exocyst complex component 1;K16461|3|2e-178|628|pss:102445462|centrosomal protein CEP135 - - - "gi|148682581|gb|EDL14528.1|/0/testis specific 10, isoform CRA_a, partial [Mus musculus]" 76491 1490 8.9 10 0.168122759 Up 0.303838053 Abhd14b abhydrolase domain containing 14b K13706|1|8e-108|393|mmu:76491|abhydrolase domain-containing protein 14 GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity - "gi|148689194|gb|EDL21141.1|/3.88531e-110/abhydrolase domain containing 14b, isoform CRA_b [Mus musculus]" 66911 1302.13 8.79 9.886666667 0.169621027 Up 0.303838053 Nudt16l1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 K16867|1|6e-109|396|cge:100772569|NUDT16-like protein 1 - - - - 69934 2023 2.156666667 2.666666667 0.306234288 Up 0.303753432 Trmt10b tRNA methyltransferase 10B K15445|1|1e-25|120|aqu:105313065|tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221] - GO:0016741 GO:0008152//metabolic process gi|31560100|ref|NP_081542.2|/7.93953e-160/tRNA methyltransferase 10 homolog B [Mus musculus] 230752 1363 7.28 8.27 0.183948879 Up 0.303715822 Eva1b eva-1 homolog B (C. elegans) - - - - gi|26024305|ref|NP_742157.1|/5.62005e-28/protein eva-1 homolog B [Mus musculus] 22163 1155 0.3 0.583333333 0.959358016 Up 0.303697018 Tnfrsf4 "tumor necrosis factor receptor superfamily, member 4" K05142|1|1e-140|501|mmu:22163|tumor necrosis factor receptor superfamily member 4 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0005035//death receptor activity;GO:0005488//binding "GO:0006351//transcription, DNA-templated;GO:0050663//cytokine secretion;GO:0048305//immunoglobulin secretion;GO:0030888//regulation of B cell proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0042110//T cell activation;GO:0001932//regulation of protein phosphorylation;GO:0044092//negative regulation of molecular function;GO:0070229//negative regulation of lymphocyte apoptotic process;GO:0006952//defense response" gi|6755909|ref|NP_035789.1|/1.23279e-139/tumor necrosis factor receptor superfamily member 4 precursor [Mus musculus] 17121 1299 6.383333333 7.283333333 0.190288888 Up 0.303659408 Mxd3 Max dimerization protein 3 K09114|1|2e-75|285|mmu:17121|MAX dimerization protein - GO:0005515//protein binding "GO:0006351//transcription, DNA-templated" gi|40254561|ref|NP_057871.2|/1.66175e-74/max dimerization protein 3 [Mus musculus] 73720 3951 1.236666667 0.866666667 -0.512907564 Down 0.303650006 Cst6 cystatin E/M K13902|1|3e-70|270|mmu:73720|cystatin-M GO:0005856//cytoskeleton GO:0004866//endopeptidase inhibitor activity GO:0009888//tissue development gi|21312060|ref|NP_082899.1|/2.17165e-69/cystatin-M precursor [Mus musculus] 320485 1336 0.446666667 0.753333333 0.754089772 Up 0.303537177 B230312C02Rik RIKEN cDNA B230312C02 gene - - - - - 23825 853.5 70.14 76.29 0.121256532 Up 0.303527775 Banf1 barrier to autointegration factor 1 - GO:0043232;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0043232;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0043232;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0043232;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process;GO:0051707//response to other organism;GO:0051707//response to other organism;GO:0006259//DNA metabolic process;GO:0019043//establishment of viral latency;GO:0051707//response to other organism;GO:0006259//DNA metabolic process;GO:0019043//establishment of viral latency;GO:0051707//response to other organism;GO:0006259//DNA metabolic process;GO:0019043//establishment of viral latency gi|470598522|ref|XP_004332472.1|/1.52095e-64/PREDICTED: LOW QUALITY PROTEIN: barrier to autointegration factor 1 [Tursiops truncatus] 381406 1888 4.933333333 5.706666667 0.210085526 Up 0.303527775 Trp53rka transformation related protein 53 regulating kinase A K08851|1|1e-119|433|mmu:381406|TP53 regulating kinase and related kinases [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004672//protein kinase activity;GO:0005515//protein binding GO:0008610//lipid biosynthetic process;GO:0006464//cellular protein modification process gi|568918806|ref|XP_006500434.1|/2.8094e-119/PREDICTED: TP53-regulating kinase isoform X1 [Mus musculus] 72108 4267 4.953333333 5.72 0.207615437 Up 0.303527775 Ddhd2 DDHD domain containing 2 K16545|1|0.0|1315|mmu:72108|phospholipase DDHD2 [EC:3.1.1.-] - GO:0043169//cation binding - "gi|28374267|gb|AAH46229.1|/0/Ddhd2 protein, partial [Mus musculus]" 105377 3742 2.236666667 2.76 0.303318001 Up 0.303499567 Slf1 SMC5-SMC6 complex localization factor 1 "K10683|1|2e-19|101|dre:100147913|BRCA1-associated RING domain protein 1;K09257|2|2e-19|101|asn:102377240|NF-kappa-B inhibitor-like protein 2;K09663|3|2e-19|100|tru:101078418|beta-1,6-N-acetylglucosaminyltransferase 4 [EC:2.4.1.-]" - - - - 319939 7483 2.8 2.28 -0.296393003 Down 0.303499567 Tns3 tensin 3 K18080|1|0.0|2841|mmu:319939|tensin - - - - 67196 1073.63 3.4 2.826666667 -0.266432982 Down 0.303424348 Ube2t ubiquitin-conjugating enzyme E2T K13960|1|2e-115|417|mmu:67196|ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23] - - - - 11550 2394 2.816666667 3.386666667 0.265877156 Up 0.303424348 Adra1d "adrenergic receptor, alpha 1d" K04137|1|0.0|827|mmu:11550|adrenergic receptor alpha-1D GO:0016021//integral component of membrane;GO:0044444//cytoplasmic part GO:0004936//alpha-adrenergic receptor activity "GO:0001983;GO:0044260;GO:0003014//renal system process;GO:0019229//regulation of vasoconstriction;GO:0044767//single-organism developmental process;GO:0003321;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0008283//cell proliferation" gi|110347547|ref|NP_038488.4|/0/alpha-1D adrenergic receptor [Mus musculus] 13838 6328 2.743333333 3.316666667 0.273804095 Up 0.303424348 Epha4 Eph receptor A4 K05105|1|0.0|1958|mmu:13838|Eph receptor A4 [EC:2.7.10.1] GO:0033267;GO:0030426//growth cone;GO:0031966//mitochondrial membrane;GO:0044327//dendritic spine head;GO:0016021//integral component of membrane;GO:0005769//early endosome;GO:0043025//neuronal cell body;GO:0097060//synaptic membrane GO:0005102//receptor binding;GO:0005003//ephrin receptor activity;GO:0032550;GO:0019904//protein domain specific binding GO:0045685//regulation of glial cell differentiation;GO:0048814//regulation of dendrite morphogenesis;GO:0007411//axon guidance;GO:0021952//central nervous system projection neuron axonogenesis;GO:0031103//axon regeneration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0043406//positive regulation of MAP kinase activity;GO:0031346//positive regulation of cell projection organization;GO:0016477//cell migration;GO:0022610;GO:0008344//adult locomotory behavior;GO:0007413//axonal fasciculation gi|34328113|ref|NP_031962.2|/0/ephrin type-A receptor 4 precursor [Mus musculus] 109815 1208 19.08 20.95666667 0.135348091 Up 0.303339727 Vimp VCP-interacting membrane protein K14025|1|8e-73|276|mmu:109815|selenoprotein S - - - - 102414 2494 17.99333333 19.87333333 0.143371399 Up 0.303339727 Clk3 CDC-like kinase 3 K08823|1|0.0|1032|mmu:102414|CDC-like kinase [EC:2.7.12.1] GO:0005856//cytoskeleton;GO:0031981//nuclear lumen GO:0004672//protein kinase activity GO:0006468//protein phosphorylation;GO:0008380//RNA splicing gi|83745112|ref|NP_031739.3|/0/dual specificity protein kinase CLK3 [Mus musculus] 56422 2791.71 27.78666667 30.49666667 0.134258786 Up 0.303302117 Hbs1l Hbs1-like (S. cerevisiae) K14416|1|0.0|785|oas:101109622|elongation factor 1 alpha-like protein - GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:1901363//heterocyclic compound binding;GO:0097159//organic cyclic compound binding GO:0010467//gene expression;GO:0007154//cell communication gi|223634002|ref|NP_001138681.1|/0/HBS1-like protein isoform 3 [Mus musculus] 19126 3557 0.523333333 0.26 -1.00921853 Down 0.303264508 Prom1 prominin 1 K06532|1|0.0|1392|mmu:19126|prominin 1 GO:0031988//membrane-bounded vesicle;GO:0016021//integral component of membrane;GO:0001750//photoreceptor outer segment;GO:0044459;GO:0005902//microvillus;GO:0044421;GO:0031988//membrane-bounded vesicle;GO:0016021//integral component of membrane;GO:0001750//photoreceptor outer segment;GO:0044459;GO:0005902//microvillus;GO:0044421;GO:0031988//membrane-bounded vesicle;GO:0016021//integral component of membrane;GO:0001750//photoreceptor outer segment;GO:0044459;GO:0005902//microvillus;GO:0044421;GO:0031988//membrane-bounded vesicle;GO:0016021//integral component of membrane;GO:0001750//photoreceptor outer segment;GO:0044459;GO:0005902//microvillus;GO:0044421;GO:0031988//membrane-bounded vesicle;GO:0016021//integral component of membrane;GO:0001750//photoreceptor outer segment;GO:0044459;GO:0005902//microvillus;GO:0044421;GO:0031988//membrane-bounded vesicle;GO:0016021//integral component of membrane;GO:0001750//photoreceptor outer segment;GO:0044459;GO:0005902//microvillus;GO:0044421;GO:0031988//membrane-bounded vesicle;GO:0016021//integral component of membrane;GO:0001750//photoreceptor outer segment;GO:0044459;GO:0005902//microvillus;GO:0044421;GO:0031988//membrane-bounded vesicle;GO:0016021//integral component of membrane;GO:0001750//photoreceptor outer segment;GO:0044459;GO:0005902//microvillus;GO:0044421 GO:0008092//cytoskeletal protein binding;GO:0050839//cell adhesion molecule binding;GO:0008092//cytoskeletal protein binding;GO:0050839//cell adhesion molecule binding;GO:0008092//cytoskeletal protein binding;GO:0050839//cell adhesion molecule binding;GO:0008092//cytoskeletal protein binding;GO:0050839//cell adhesion molecule binding;GO:0008092//cytoskeletal protein binding;GO:0050839//cell adhesion molecule binding;GO:0008092//cytoskeletal protein binding;GO:0050839//cell adhesion molecule binding;GO:0008092//cytoskeletal protein binding;GO:0050839//cell adhesion molecule binding;GO:0008092//cytoskeletal protein binding;GO:0050839//cell adhesion molecule binding GO:0003407//neural retina development;GO:0072311;GO:0007601//visual perception;GO:0001754//eye photoreceptor cell differentiation;GO:0072160//nephron tubule epithelial cell differentiation;GO:0061318;GO:0003407//neural retina development;GO:0072311;GO:0007601//visual perception;GO:0001754//eye photoreceptor cell differentiation;GO:0072160//nephron tubule epithelial cell differentiation;GO:0061318;GO:0003407//neural retina development;GO:0072311;GO:0007601//visual perception;GO:0001754//eye photoreceptor cell differentiation;GO:0072160//nephron tubule epithelial cell differentiation;GO:0061318;GO:0003407//neural retina development;GO:0072311;GO:0007601//visual perception;GO:0001754//eye photoreceptor cell differentiation;GO:0072160//nephron tubule epithelial cell differentiation;GO:0061318;GO:0003407//neural retina development;GO:0072311;GO:0007601//visual perception;GO:0001754//eye photoreceptor cell differentiation;GO:0072160//nephron tubule epithelial cell differentiation;GO:0061318;GO:0003407//neural retina development;GO:0072311;GO:0007601//visual perception;GO:0001754//eye photoreceptor cell differentiation;GO:0072160//nephron tubule epithelial cell differentiation;GO:0061318;GO:0003407//neural retina development;GO:0072311;GO:0007601//visual perception;GO:0001754//eye photoreceptor cell differentiation;GO:0072160//nephron tubule epithelial cell differentiation;GO:0061318;GO:0003407//neural retina development;GO:0072311;GO:0007601//visual perception;GO:0001754//eye photoreceptor cell differentiation;GO:0072160//nephron tubule epithelial cell differentiation;GO:0061318 "gi|148705655|gb|EDL37602.1|/0/prominin 1, isoform CRA_c, partial [Mus musculus]" 433752 1919 1.5 1.103333333 -0.443093784 Down 0.303226898 AA415398 expressed sequence AA415398 - - - - gi|51921351|ref|NP_001004178.1|/1.0871e-110/uncharacterized protein LOC433752 [Mus musculus] 213575 1378 1.99 2.483333333 0.319509494 Up 0.303189289 Dync2li1 dynein cytoplasmic 2 light intermediate chain 1 "K10417|1|0.0|706|mmu:213575|dynein light intermediate chain 2, cytosolic" GO:0005875//microtubule associated complex;GO:0072372//primary cilium;GO:0005930//axoneme GO:0017111//nucleoside-triphosphatase activity GO:0010927;GO:0009855//determination of bilateral symmetry gi|26986541|ref|NP_758460.1|/0/cytoplasmic dynein 2 light intermediate chain 1 [Mus musculus] 13716 3085 11.01333333 12.26666667 0.15549208 Up 0.303161082 Ell elongation factor RNA polymerase II K15183|1|0.0|1055|mmu:13716|RNA polymerase II elongation factor ELL GO:0043234//protein complex;GO:0016604//nuclear body GO:0019899//enzyme binding "GO:0044764;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0010921//regulation of phosphatase activity" gi|124358953|ref|NP_031950.2|/0/RNA polymerase II elongation factor ELL [Mus musculus] 23996 1436 70.22333333 76.13 0.116514599 Up 0.303161082 Psmc4 "proteasome (prosome, macropain) 26S subunit, ATPase, 4" K03063|1|0.0|758|rno:117262|26S proteasome regulatory subunit T3 GO:0031981//nuclear lumen;GO:0000502//proteasome complex;GO:0044444//cytoplasmic part GO:0017111//nucleoside-triphosphatase activity;GO:0032550 "GO:0006915//apoptotic process;GO:0001701//in utero embryonic development;GO:0044764;GO:0006520//cellular amino acid metabolic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0044772//mitotic cell cycle phase transition;GO:0009154//purine ribonucleotide catabolic process;GO:0016070//RNA metabolic process;GO:0051320;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle" gi|625205142|ref|XP_007643926.1|/0/PREDICTED: 26S protease regulatory subunit 6B isoform X1 [Cricetulus griseus] 17246 3124 18.66666667 20.54 0.137971855 Up 0.303151679 Mdm2 transformed mouse 3T3 cell double minute 2 K06643|1|0.0|803|mmu:17246|E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27] GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0019787//ubiquitin-like protein transferase activity;GO:0005102//receptor binding;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0005102//receptor binding;GO:0046914//transition metal ion binding "GO:0009057//macromolecule catabolic process;GO:0006915//apoptotic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016485//protein processing;GO:0016567//protein ubiquitination;GO:0033365//protein localization to organelle;GO:0006351//transcription, DNA-templated;GO:0006611//protein export from nucleus;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0018193//peptidyl-amino acid modification;GO:0007050//cell cycle arrest;GO:0031331;GO:0065003;GO:0031647//regulation of protein stability;GO:0009057//macromolecule catabolic process;GO:0006915//apoptotic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016485//protein processing;GO:0016567//protein ubiquitination;GO:0033365//protein localization to organelle;GO:0006351//transcription, DNA-templated;GO:0006611//protein export from nucleus;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0018193//peptidyl-amino acid modification;GO:0007050//cell cycle arrest;GO:0031331;GO:0065003;GO:0031647//regulation of protein stability" gi|6754672|ref|NP_034916.1|/0/E3 ubiquitin-protein ligase Mdm2 isoform 1 [Mus musculus] 15384 2462.67 66.35 72.25333333 0.122967681 Up 0.303142277 Hnrnpab heterogeneous nuclear ribonucleoprotein A/B K13044|1|2e-116|422|rno:83498|heterogeneous nuclear ribonucleoprotein A/B/D GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0036094//small molecule binding;GO:0003723//RNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0036094//small molecule binding "GO:0006351//transcription, DNA-templated;GO:0000904//cell morphogenesis involved in differentiation;GO:0006351//transcription, DNA-templated;GO:0000904//cell morphogenesis involved in differentiation" gi|140971918|ref|NP_112620.2|/6.46129e-109/heterogeneous nuclear ribonucleoprotein A/B [Rattus norvegicus] 17686 3945 2.153333333 1.69 -0.349548418 Down 0.303132874 Msh3 mutS homolog 3 K08736|1|0.0|2090|mmu:17686|DNA mismatch repair protein MSH3 - GO:0032550;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0000217//DNA secondary structure binding;GO:0003690//double-stranded DNA binding;GO:0032550;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0000217//DNA secondary structure binding;GO:0003690//double-stranded DNA binding GO:0002566//somatic diversification of immune receptors via somatic mutation;GO:0000018//regulation of DNA recombination;GO:0002562;GO:0051095;GO:0006281//DNA repair;GO:0002566//somatic diversification of immune receptors via somatic mutation;GO:0000018//regulation of DNA recombination;GO:0002562;GO:0051095;GO:0006281//DNA repair gi|68299763|ref|NP_034959.2|/0/DNA mismatch repair protein Msh3 isoform 1 [Mus musculus] 59016 1848 13.17666667 14.65666667 0.153571577 Up 0.303038851 Thap11 THAP domain containing 11 - GO:0044424 - - gi|594627185|ref|XP_007198203.1|/7.52921e-103/PREDICTED: THAP domain-containing protein 11 [Balaenoptera acutorostrata scammoni] 100710 7311 2.03 1.583333333 -0.358514715 Down 0.302991839 Pds5b PDS5 cohesin associated factor B K11267|1|0.0|2700|mmu:100710|sister chromatid cohesion protein PDS5 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0008283//cell proliferation;GO:0000070//mitotic sister chromatid segregation gi|66955886|ref|NP_780519.3|/0/sister chromatid cohesion protein PDS5 homolog B [Mus musculus] 67020 1585 28.76666667 31.44 0.128203159 Up 0.302907217 Tmem88 transmembrane protein 88 K11448|1|1e-22|110|cge:100756212|lysine-specific demethylase 6B [EC:1.14.11.-] - - - gi|255003750|ref|NP_080191.3|/3.40469e-43/transmembrane protein 88 [Mus musculus] 74601 1475 0.31 0.593333333 0.93657462 Up 0.302841401 4833427F10Rik RIKEN cDNA 4833427F10 gene - - - - - 12295 2082.83 4.19 3.546666667 -0.240486499 Down 0.302831998 Cacnb1 "calcium channel, voltage-dependent, beta 1 subunit" K04862|1|0.0|989|rno:50688|voltage-dependent calcium channel beta-1 GO:0034704//calcium channel complex;GO:0042383//sarcolemma;GO:0005783//endoplasmic reticulum;GO:0034704//calcium channel complex;GO:0042383//sarcolemma;GO:0005783//endoplasmic reticulum;GO:0034704//calcium channel complex;GO:0042383//sarcolemma;GO:0005783//endoplasmic reticulum;GO:0034704//calcium channel complex;GO:0042383//sarcolemma;GO:0005783//endoplasmic reticulum;GO:0034704//calcium channel complex;GO:0042383//sarcolemma;GO:0005783//endoplasmic reticulum GO:0019900//kinase binding;GO:0005245//voltage-gated calcium channel activity;GO:0019900//kinase binding;GO:0005245//voltage-gated calcium channel activity;GO:0019900//kinase binding;GO:0005245//voltage-gated calcium channel activity;GO:0019900//kinase binding;GO:0005245//voltage-gated calcium channel activity;GO:0019900//kinase binding;GO:0005245//voltage-gated calcium channel activity GO:0006935//chemotaxis;GO:0006605//protein targeting;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0006935//chemotaxis;GO:0006605//protein targeting;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0006605//protein targeting;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0006935//chemotaxis;GO:0006605//protein targeting;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0006935//chemotaxis;GO:0006605//protein targeting;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport gi|33146398|dbj|BAC80138.1|/0/voltage-dependent calcium channel beta1 subunit [Mus musculus] 67848 2806 3.553333333 4.196666667 0.240070845 Up 0.302831998 Ddx55 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 K14809|1|0.0|1063|mmu:67848|ATP-dependent RNA helicase DDX55/SPB4 [EC:3.6.4.13] - "GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550" - gi|74181724|dbj|BAE32574.1|/0/unnamed protein product [Mus musculus] 67657 2022 4.12 3.476666667 -0.244939585 Down 0.302831998 Rabl3 "RAB, member RAS oncogene family-like 3" K07933|1|3e-125|451|mmu:67657|Rab-like protein 3 - GO:0032550 GO:0035556//intracellular signal transduction gi|109948290|ref|NP_001035964.1|/2.41741e-124/rab-like protein 3 [Mus musculus] 227721 1824 18.63666667 20.48666667 0.136541422 Up 0.302813193 Plpp7 phospholipid phosphatase 7 (inactive) K17981|1|1e-11|73.9|cel:CELE_T13C5.6|mitochondrial fission process protein 1 - - - - 230991 2169 0.723333333 1.076666667 0.573839122 Up 0.302794389 B930041F14Rik fibronectin type III domain containing 10 K11094|1|6e-14|82.0|tup:102471655|U2 small nuclear ribonucleoprotein B'';K15544|2|2e-11|73.6|gfr:102036773|RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16] - - - gi|325995130|ref|NP_848814.3|/3.45246e-108/fibronectin type-III domain-containing transmembrane protein C1orf233 homolog precursor [Mus musculus] 230801 2733.36 6.403333333 7.29 0.187095701 Up 0.302794389 Pigv "phosphatidylinositol glycan anchor biosynthesis, class V" "K07542|1|1e-52|210|mmu:230801|phosphatidylinositol glycan, class V [EC:2.4.1.-]" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0016758//transferase activity, transferring hexosyl groups;GO:0016758//transferase activity, transferring hexosyl groups;GO:0016758//transferase activity, transferring hexosyl groups" GO:0006497//protein lipidation;GO:0006497//protein lipidation;GO:0006497//protein lipidation gi|225543179|ref|NP_001139428.1|/1.30107e-65/GPI mannosyltransferase 2 isoform 3 [Mus musculus] 80889 3847 6.266666667 7.156666667 0.191589529 Up 0.302794389 Mesdc1 mesoderm development candidate 1 K06271|1|2e-25|121|aqu:100641624|talin - - - - 78895 2848 0.996666667 0.656666667 -0.601949855 Down 0.302766182 Pus7l pseudouridylate synthase 7-like K06176|1|0.0|1377|mmu:78895|tRNA pseudouridine13 synthase [EC:5.4.99.27] - - - - 11541 1844 0.403333333 0.7 0.79538228 Up 0.302766182 Adora2b adenosine A2b receptor K04267|1|1e-178|629|mmu:11541|adenosine receptor A2b GO:0031224//intrinsic component of membrane;GO:0044464 GO:0004930//G-protein coupled receptor activity GO:0002545;GO:0035588;GO:0042311//vasodilation;GO:0001819//positive regulation of cytokine production;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0006182//cGMP biosynthetic process;GO:0008283//cell proliferation;GO:0001525//angiogenesis;GO:0010558;GO:0033008;GO:0006694//steroid biosynthetic process;GO:0006171//cAMP biosynthetic process;GO:0031281//positive regulation of cyclase activity;GO:0014061//regulation of norepinephrine secretion gi|31560741|ref|NP_031439.2|/9.83363e-178/adenosine receptor A2b [Mus musculus] 21885 3661.63 3.303333333 3.916666667 0.245703794 Up 0.302747377 Tle1 transducin-like enhancer of split 1 K04497|1|0.0|1025|dre:30206|groucho GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding;GO:0001104//RNA polymerase II transcription cofactor activity GO:0007166//cell surface receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043066//negative regulation of apoptotic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043066//negative regulation of apoptotic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0007166//cell surface receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043066//negative regulation of apoptotic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043066//negative regulation of apoptotic process;GO:0006366//transcription from RNA polymerase II promoter "gi|148699118|gb|EDL31065.1|/0/mCG2299, isoform CRA_d, partial [Mus musculus]" 83703 2103 3.79 3.176666667 -0.254684135 Down 0.302747377 Dbr1 debranching RNA lariats 1 K18328|1|0.0|1110|mmu:83703|lariat debranching enzyme [EC:3.1.-.-] - - - - 208624 1425 10.34 11.58333333 0.163814291 Up 0.30271917 Alg3 "asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)" "K03845|1|0.0|718|mmu:208624|alpha-1,3-mannosyltransferase [EC:2.4.1.258]" - - - - 66713 3688 11.6 10.36333333 -0.162636689 Down 0.30271917 Actr2 ARP2 actin-related protein 2 K17260|1|0.0|759|mdo:100033310|actin-related protein 2 GO:0030864//cortical actin cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0032550 GO:0046907//intracellular transport;GO:0045010//actin nucleation gi|5031571|ref|NP_005713.1|/0/actin-related protein 2 isoform b [Homo sapiens] 26407 5305 14.69666667 13.23 -0.151675915 Down 0.302625146 Map3k4 mitogen-activated protein kinase kinase kinase 4 K04428|1|0.0|2982|mmu:26407|mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25] GO:0044424 GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0043169//cation binding GO:0007542;GO:0010467//gene expression;GO:0043406//positive regulation of MAP kinase activity;GO:0030154//cell differentiation;GO:0044767//single-organism developmental process;GO:0009953//dorsal/ventral pattern formation gi|93102421|ref|NP_036078.2|/0/mitogen-activated protein kinase kinase kinase 4 [Mus musculus] 17474 1336 0.41 0.706666667 0.785405949 Up 0.302437098 Clec4d "C-type lectin domain family 4, member d" K10058|1|3e-133|477|mmu:17474|C-type lectin domain family 4 member D - - - - 70544 971 67.33 72.92 0.115065097 Up 0.302437098 Tmem242 transmembrane protein 242 - GO:0031224//intrinsic component of membrane - - gi|26366492|dbj|BAC25272.1|/1.53176e-75/unnamed protein product [Mus musculus] 70747 4261 1.98 1.536666667 -0.36569618 Down 0.302352477 Tspan2 tetraspanin 2 K17354|1|2e-103|380|mmu:70747|tetraspanin-2 GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464 - - gi|70608157|ref|NP_081809.2|/1.12246e-103/tetraspanin-2 isoform 1 [Mus musculus] 245269 4103 1.513333333 1.953333333 0.368208367 Up 0.302352477 Nim1k NIM1 serine/threonine protein kinase K16310|1|0.0|879|mmu:245269|serine/threonine-protein kinase NIM1 [EC:2.7.11.1] - GO:0046872//metal ion binding;GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process "gi|148686387|gb|EDL18334.1|/0/RIKEN cDNA E130304F04, isoform CRA_a, partial [Mus musculus]" 100036521 2186 3.536666667 2.956666667 -0.258418647 Down 0.302324269 Umad1 UMAP1-MVP12 associated (UMA) domain containing 1 - - - - gi|696221387|ref|NP_001289282.1|/3.10232e-83/uncharacterized protein LOC100036521 isoform 1 [Mus musculus] 67201 2523 13.71 15.17333333 0.146309486 Up 0.302324269 Glod4 glyoxalase domain containing 4 K13132|1|6e-99|364|gfr:102035978|gem associated protein 4 GO:0043231//intracellular membrane-bounded organelle - - gi|255003777|ref|NP_080305.2|/1.18242e-171/glyoxalase domain-containing protein 4 [Mus musculus] 234463 2701 3.5 2.92 -0.261386553 Down 0.302324269 Tmem184c transmembrane protein 184C K14360|1|4e-16|89.7|sko:100372211|organic solute transporter subunit alpha - - - gi|568956502|ref|XP_006530916.1|/0/PREDICTED: transmembrane protein 184C isoform X1 [Mus musculus] 381217 2565 27.56 30.17 0.130538808 Up 0.302296062 Fam189a2 "family with sequence similarity 189, member A2" - - - - gi|166795257|ref|NP_001107646.1|/0/protein FAM189A2 [Mus musculus] 14913 910 0.11 0.33 1.584962501 Up 0.302239648 Guca1a guanylate cyclase activator 1a (retina) K08328|1|4e-105|383|mmu:14913|guanylate cyclase activator 1 - - - - 245866 2124 11.48666667 10.26 -0.16292947 Down 0.302202038 Ift52 intraflagellar transport 52 K19681|1|0.0|807|mmu:245866|intraflagellar transport protein 52 GO:0030425//dendrite;GO:0031513//nonmotile primary cilium - GO:0003002//regionalization;GO:0003143//embryonic heart tube morphogenesis;GO:0006508//proteolysis;GO:0007166//cell surface receptor signaling pathway;GO:0009855//determination of bilateral symmetry;GO:0030326//embryonic limb morphogenesis "gi|148674367|gb|EDL06314.1|/0/intraflagellar transport 52 homolog (Chlamydomonas), isoform CRA_a, partial [Mus musculus]" 320352 2103 0.363333333 0.656666667 0.853867495 Up 0.302155027 Lrrc31 leucine rich repeat containing 31 K16634|1|7e-15|85.1|phi:102101520|ribonuclease inhibitor - - - gi|822606534|ref|NP_001296162.1|/0/leucine rich repeat containing 31 [Mus musculus] 72554 2431 8.16 7.186666667 -0.18324638 Down 0.30208921 Utp14a UTP14A small subunit processome component K14567|1|0.0|1233|mmu:72554|U3 small nucleolar RNA-associated protein 14 GO:0043231//intracellular membrane-bounded organelle;GO:0030684//preribosome - GO:0042254//ribosome biogenesis gi|50510433|dbj|BAD32202.1|/0/mKIAA0266 protein [Mus musculus] 70497 3540.47 8.133333333 7.16 -0.183887154 Down 0.30208921 Arhgap17 Rho GTPase activating protein 17 K19269|1|1e-112|253|pbi:103065057|phosphoglycolate phosphatase [EC:3.1.3.18 3.1.3.48];K18470|3|2e-21|107|ola:101165860|Rho GTPase-activating protein 1;K07526|4|2e-21|107|pxy:105396432|SLIT-ROBO Rho GTPase activating protein GO:0043296//apical junction complex;GO:0044424;GO:0043296//apical junction complex;GO:0044424;GO:0043296//apical junction complex;GO:0044424;GO:0043296//apical junction complex;GO:0044424;GO:0043296//apical junction complex;GO:0044424 GO:0019904//protein domain specific binding;GO:0008047//enzyme activator activity;GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding;GO:0008047//enzyme activator activity;GO:0019904//protein domain specific binding GO:0006887//exocytosis;GO:0007154//cell communication;GO:0030036//actin cytoskeleton organization;GO:0006887//exocytosis;GO:0007154//cell communication;GO:0030036//actin cytoskeleton organization;GO:0006887//exocytosis;GO:0007154//cell communication;GO:0030036//actin cytoskeleton organization;GO:0006887//exocytosis;GO:0007154//cell communication;GO:0030036//actin cytoskeleton organization;GO:0006887//exocytosis;GO:0007154//cell communication;GO:0030036//actin cytoskeleton organization gi|169790947|ref|NP_001116115.1|/0/rho GTPase-activating protein 17 isoform e [Mus musculus] 106581 2819.5 61.26 66.68 0.122308737 Up 0.302032796 Fam234a "family with sequence similarity 234, member A" K17258|1|0.0|1052|mmu:106581|integrin alpha FG-GAP repeat containing protein 3 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148690552|gb|EDL22499.1|/0/integrin alpha FG-GAP repeat containing 3, isoform CRA_b, partial [Mus musculus]" 217140 1534 9.68 8.606666667 -0.169552453 Down 0.301985784 Scrn2 secernin 2 K14358|1|0.0|753|mmu:217140|secernin - GO:0008238//exopeptidase activity GO:0019538//protein metabolic process "gi|148684117|gb|EDL16064.1|/0/secernin 2, isoform CRA_c [Mus musculus]" 67222 1463 8.333333333 9.403333333 0.174278571 Up 0.301985784 Srfbp1 serum response factor binding protein 1 K07520|1|1e-37|160|asn:102382159|actin-binding LIM protein GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated" gi|74202622|dbj|BAE24868.1|/0/unnamed protein product [Mus musculus] 56525 3521 0.96 1.336666667 0.477533425 Up 0.301938772 Zfp235 zinc finger protein 235 K09228|1|0.0|1512|mmu:56525|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|755519929|ref|XP_011248958.1|/0/PREDICTED: zinc finger protein 235 isoform X3 [Mus musculus] 13026 4793.05 29.58 27.00333333 -0.131484546 Down 0.301929369 Pcyt1a "phosphate cytidylyltransferase 1, choline, alpha isoform" K00968|1|0.0|644|mmu:13026|choline-phosphate cytidylyltransferase [EC:2.7.7.15] GO:0044425;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane;GO:0044425;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane;GO:0044425;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane GO:0042802//identical protein binding;GO:0070567;GO:0042802//identical protein binding;GO:0070567;GO:0042802//identical protein binding;GO:0070567 GO:0050896//response to stimulus;GO:0006656//phosphatidylcholine biosynthetic process;GO:0050896//response to stimulus;GO:0006656//phosphatidylcholine biosynthetic process;GO:0050896//response to stimulus;GO:0006656//phosphatidylcholine biosynthetic process gi|6753552|ref|NP_034111.1|/0/choline-phosphate cytidylyltransferase A [Mus musculus] 59029 1560 17.62333333 19.43666667 0.141293996 Up 0.301835345 Psmd14 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 14" K03030|1|3e-165|583|pale:102887112|26S proteasome regulatory subunit N11 GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0005838//proteasome regulatory particle "GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0061135;GO:0016790//thiolester hydrolase activity;GO:0043169//cation binding;GO:0032403//protein complex binding" "GO:0010952//positive regulation of peptidase activity;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0000726;GO:0000725//recombinational repair;GO:0016579//protein deubiquitination;GO:0044772//mitotic cell cycle phase transition;GO:0006915//apoptotic process;GO:0044764;GO:0051320;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator" "gi|148695032|gb|EDL26979.1|/2.91168e-164/proteasome (prosome, macropain) 26S subunit, non-ATPase, 14, isoform CRA_a [Mus musculus]" 67477 3249 1.3 1.72 0.403896942 Up 0.301825943 Abhd15 abhydrolase domain containing 15 K13707|1|0.0|828|mmu:67477|abhydrolase domain-containing protein 15 - GO:0052689//carboxylic ester hydrolase activity - gi|147902337|ref|NP_080461.3|/0/protein ABHD15 precursor [Mus musculus] 17855 1737.94 4.206666667 4.903333333 0.221085336 Up 0.301769529 Mvk mevalonate kinase K00869|1|0.0|722|mmu:17855|mevalonate kinase [EC:2.7.1.36] GO:0042579//microbody;GO:0042579//microbody GO:0016301//kinase activity;GO:0032550;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0016301//kinase activity;GO:0032550;GO:0005515//protein binding;GO:0003723//RNA binding GO:0006412//translation;GO:0006796//phosphate-containing compound metabolic process;GO:0006084//acetyl-CoA metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0006720//isoprenoid metabolic process;GO:0006954//inflammatory response;GO:0006412//translation;GO:0006796//phosphate-containing compound metabolic process;GO:0006084//acetyl-CoA metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0006720//isoprenoid metabolic process;GO:0006954//inflammatory response gi|808176003|ref|NP_001293134.1|/0/mevalonate kinase isoform 1 [Mus musculus] 320678 2988.94 5.343333333 6.15 0.202846391 Up 0.301760126 Iffo1 intermediate filament family orphan 1 "K07606|1|5e-07|59.7|cmy:102943042|vimentin;K04573|3|9e-07|58.9|cmk:103191035|neurofilament medium polypeptide (neurofilament 3);K07608|5|9e-07|58.9|dre:555251|internexin neuronal intermediate filament protein, alpha" - - - "gi|148667393|gb|EDK99809.1|/0/RIKEN cDNA A930037G23, isoform CRA_c, partial [Mus musculus]" 22339 3321.78 64.64 59.36666667 -0.122774087 Down 0.301713114 Vegfa vascular endothelial growth factor A K05448|1|3e-129|454|tup:102499303|vascular endothelial growth factor A "GO:0005578//proteinaceous extracellular matrix;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0042802//identical protein binding;GO:0005172//vascular endothelial growth factor receptor binding;GO:0046983//protein dimerization activity;GO:0005539//glycosaminoglycan binding GO:0006915//apoptotic process;GO:0030218//erythrocyte differentiation;GO:0008585//female gonad development;GO:0002551//mast cell chemotaxis;GO:0006461//protein complex assembly;GO:0060562//epithelial tube morphogenesis;GO:0021700//developmental maturation;GO:0001945//lymph vessel development;GO:0048738//cardiac muscle tissue development;GO:0002573//myeloid leukocyte differentiation;GO:0007589//body fluid secretion;GO:0002090//regulation of receptor internalization;GO:0048771//tissue remodeling;GO:0038089//positive regulation of cell migration by vascular endothelial growth factor signaling pathway;GO:0045860//positive regulation of protein kinase activity;GO:0043010//camera-type eye development;GO:0008284//positive regulation of cell proliferation;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0031954//positive regulation of protein autophosphorylation;GO:0043009//chordate embryonic development;GO:0030324//lung development;GO:0001954//positive regulation of cell-matrix adhesion;GO:0043488//regulation of mRNA stability;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:0001754//eye photoreceptor cell differentiation;GO:0032845;GO:0048845//venous blood vessel morphogenesis;GO:0043114//regulation of vascular permeability;GO:0090045//positive regulation of deacetylase activity;GO:0001666//response to hypoxia;GO:0048844//artery morphogenesis;GO:0002040//sprouting angiogenesis;GO:0009791//post-embryonic development;GO:0048875//chemical homeostasis within a tissue;GO:0003007//heart morphogenesis;GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;GO:0007405//neuroblast proliferation;GO:0051094//positive regulation of developmental process;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0001935//endothelial cell proliferation;GO:0050927//positive regulation of positive chemotaxis;GO:0043405//regulation of MAP kinase activity;GO:0055006//cardiac cell development;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0022604//regulation of cell morphogenesis gi|160358803|ref|NP_033531.3|/1.15153e-151/vascular endothelial growth factor A isoform 2 [Mus musculus] 230598 4155 65.10666667 59.88666667 -0.120570444 Down 0.301600286 Nrd1 "nardilysin, N-arginine dibasic convertase, NRD convertase 1" K01411|1|0.0|2200|mmu:230598|nardilysin [EC:3.4.24.61] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0004175//endopeptidase activity GO:0006509//membrane protein ectodomain proteolysis;GO:0052547//regulation of peptidase activity gi|31559918|ref|NP_666262.2|/0/nardilysin precursor [Mus musculus] 50776 1511.58 2.563333333 2.063333333 -0.313044189 Down 0.301534469 Polg2 "polymerase (DNA directed), gamma 2, accessory subunit" K02333|1|0.0|612|mmu:50776|DNA polymerase gamma 2 GO:0005759//mitochondrial matrix;GO:0005759//mitochondrial matrix GO:0005515//protein binding;GO:0034061//DNA polymerase activity;GO:0005515//protein binding;GO:0034061//DNA polymerase activity GO:0006259//DNA metabolic process;GO:0006259//DNA metabolic process "gi|239985608|ref|NP_056625.2|/0/DNA polymerase subunit gamma-2, mitochondrial [Mus musculus]" 227960 3288 3.306666667 2.743333333 -0.26944769 Down 0.301515664 Gca grancalcin "K08585|1|1e-27|128|aag:AaeL_AAEL003952|calpain, invertebrate [EC:3.4.22.-]" GO:0044444//cytoplasmic part GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0043169//cation binding - gi|21704030|ref|NP_663498.1|/3.76706e-112/grancalcin [Mus musculus] 16068 1422 8.503333333 9.56 0.168982125 Up 0.301468652 Il18bp interleukin 18 binding protein K15698|1|9e-58|226|pale:102892454|RING finger protein 121 GO:0044421 GO:0019955//cytokine binding GO:0002237//response to molecule of bacterial origin;GO:0034612//response to tumor necrosis factor;GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;GO:0034614//cellular response to reactive oxygen species gi|6754314|ref|NP_034661.1|/5.60027e-111/interleukin-18-binding protein precursor [Mus musculus] 11605 3032 1.443333333 1.876666667 0.378767897 Up 0.30145925 Gla "galactosidase, alpha" K01189|1|0.0|893|mmu:11605|alpha-galactosidase [EC:3.2.1.22] - - - gi|133778924|ref|NP_038491.2|/0/alpha-galactosidase A [Mus musculus] 75472 1034 1.46 1.07 -0.448357572 Down 0.301440445 Cfap126 cilia and flagella associated protein 126 K13101|1|1e-06|56.2|soc:105207801|G patch domain and KOW motifs-containing protein - - - - 69288 4338.31 62.29 57.12666667 -0.124836221 Down 0.301393433 Rhobtb1 Rho-related BTB domain containing 1 K07868|1|0.0|1371|mmu:69288|Rho-related BTB domain-containing protein 1/2 GO:0044464;GO:0044464;GO:0044464;GO:0044464 GO:0032550;GO:0032550;GO:0032550;GO:0032550 GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction gi|124486809|ref|NP_001074816.1|/0/rho-related BTB domain-containing protein 1 isoform 1 [Mus musculus] 56838 3753 0.6 0.316666667 -0.921997488 Down 0.301393433 Ccl28 chemokine (C-C motif) ligand 28 K05513|1|6e-56|222|mmu:56838|C-C motif chemokine 28 GO:0044421 GO:0005125//cytokine activity GO:0031667//response to nutrient levels;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0002376//immune system process;GO:0042221//response to chemical gi|9931984|ref|NP_064675.1|/4.91606e-55/C-C motif chemokine 28 precursor [Mus musculus] 22213 1982 58.25666667 63.41333333 0.122363059 Up 0.301393433 Ube2g2 ubiquitin-conjugating enzyme E2G 2 K04555|1|1e-92|343|myd:102759738|ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0032550;GO:0019787//ubiquitin-like protein transferase activity GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0006487//protein N-linked glycosylation gi|74200325|dbj|BAE22948.1|/5.08539e-138/unnamed protein product [Mus musculus] 99375 3628 30.13333333 27.60666667 -0.12634357 Down 0.301374629 Cul4a cullin 4A K10609|1|0.0|1433|mmu:99375|cullin 4 GO:0080008//Cul4-RING E3 ubiquitin ligase complex GO:0044389//ubiquitin-like protein ligase binding GO:0000084//mitotic S phase;GO:0035556//intracellular signal transduction;GO:0006259//DNA metabolic process;GO:0009896;GO:0032446//protein modification by small protein conjugation;GO:0033554//cellular response to stress;GO:0044772//mitotic cell cycle phase transition;GO:0019941//modification-dependent protein catabolic process;GO:0008283//cell proliferation gi|167466258|ref|NP_666319.2|/0/cullin-4A [Mus musculus] 64652 5606 64.70333333 59.55333333 -0.119657776 Down 0.301365226 Nisch nischarin K02603|1|3e-51|207|tsp:Tsp_03951|origin recognition complex subunit 1;K16770|2|1e-13|82.4|acs:100565670|centriolin;K16475|5|7e-13|80.1|crg:105326087|leucine-rich repeat and coiled-coil domain-containing protein 1 GO:0005768//endosome;GO:0016020//membrane GO:0005543//phospholipid binding;GO:0004930//G-protein coupled receptor activity;GO:0005102//receptor binding GO:0016477//cell migration;GO:0012501//programmed cell death;GO:0007265//Ras protein signal transduction;GO:0019318//hexose metabolic process;GO:0050804//modulation of synaptic transmission;GO:0015874//norepinephrine transport;GO:0007010//cytoskeleton organization;GO:0008015//blood circulation gi|114158672|ref|NP_073147.2|/0/nischarin [Mus musculus] 110956 3326 19.29333333 17.50666667 -0.140198006 Down 0.301327617 D17H6S56E-5 "DNA segment, Chr 17, human D6S56E 5" K10279|1|1e-07|61.6|fpg:101911127|F-box and leucine-rich repeat protein 13 - - - - 104479 3418 4.78 5.533333333 0.211138218 Up 0.30129941 Ccdc117 coiled-coil domain containing 117 - - - - gi|164698436|ref|NP_598794.2|/3.10524e-117/coiled-coil domain-containing protein 117 [Mus musculus] 66353 628 0.656666667 0.366666667 -0.840692106 Down 0.301130167 Riiad1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 - - GO:0019887//protein kinase regulator activity GO:0007154//cell communication gi|21313514|ref|NP_079782.1|/7.65369e-64/RIIa domain-containing protein 1 [Mus musculus] 212937 3498 0.753333333 1.103333333 0.550508444 Up 0.301017338 Tifab "TRAF-interacting protein with forkhead-associated domain, family member B" - - - - gi|60359824|dbj|BAD90131.1|/1.97767e-79/mFLJ00292 protein [Mus musculus] 246257 2642 3.85 4.51 0.228268988 Up 0.300998533 Ovca2 candidate tumor suppressor in ovarian cancer 2 K07561|1|1e-63|247|shr:100932196|2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108] GO:0043231//intracellular membrane-bounded organelle - GO:0033993//response to lipid gi|18158418|ref|NP_081412.1|/1.35538e-125/ovarian cancer-associated gene 2 protein homolog [Mus musculus] 12767 1821 3.806666667 4.47 0.231746587 Up 0.300998533 Cxcr4 chemokine (C-X-C motif) receptor 4 K04189|1|0.0|694|mmu:12767|C-X-C chemokine receptor type 4 GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0032182//ubiquitin-like protein binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0017022//myosin binding;GO:0004950//chemokine receptor activity GO:0007411//axon guidance;GO:0006941//striated muscle contraction;GO:0002274;GO:0012501//programmed cell death;GO:0003006//developmental process involved in reproduction;GO:0006816//calcium ion transport;GO:0007009//plasma membrane organization;GO:0008283//cell proliferation;GO:0045687//positive regulation of glial cell differentiation;GO:0019221//cytokine-mediated signaling pathway;GO:0042110//T cell activation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0008037//cell recognition;GO:0007276//gamete generation;GO:0006950//response to stress;GO:0030855//epithelial cell differentiation;GO:0019932//second-messenger-mediated signaling;GO:0021537//telencephalon development;GO:0016477//cell migration gi|116268123|ref|NP_034041.2|/0/C-X-C chemokine receptor type 4 [Mus musculus] 233826 3750 0.18 0.42 1.222392421 Up 0.300942119 Palb2 partner and localizer of BRCA2 K10897|1|0.0|706|mmu:233826|partner and localizer of BRCA2 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0009888//tissue development;GO:0001832//blastocyst growth;GO:0006259//DNA metabolic process;GO:0006915//apoptotic process;GO:0009952//anterior/posterior pattern specification;GO:0033554//cellular response to stress;GO:0009653//anatomical structure morphogenesis gi|577861014|ref|NP_001276774.1|/0/partner and localizer of BRCA2 isoform 5 [Mus musculus] 53415 1373.09 9.666666667 8.616666667 -0.16588862 Down 0.300848095 Htatip2 HIV-1 Tat interactive protein 2 K17290|1|9e-134|479|mmu:53415|oxidoreductase [EC:1.1.1.-] - - - - 77559 9625 27.90333333 25.42666667 -0.134095134 Down 0.300838693 Agl "amylo-1,6-glucosidase, 4-alpha-glucanotransferase" K01196|1|0.0|3115|mmu:77559|glycogen debranching enzyme [EC:2.4.1.25 3.2.1.33] GO:0043231//intracellular membrane-bounded organelle GO:0004133//glycogen debranching enzyme activity GO:0005977//glycogen metabolic process gi|124486747|ref|NP_001074795.1|/0/glycogen debranching enzyme [Mus musculus] 58909 4300 6.14 5.336666667 -0.202299754 Down 0.300791681 Fam13a "family with sequence similarity 13, member A" - - - - gi|23956368|ref|NP_705802.1|/0/protein FAM13A [Mus musculus] 94218 5340 5.406666667 6.21 0.199853855 Up 0.300791681 Cnnm3 cyclin M3 K16302|1|0.0|1074|mmu:94218|metal transporter CNNM GO:0031224//intrinsic component of membrane;GO:0016020//membrane GO:0005488//binding;GO:0005488//binding GO:0044765//single-organism transport;GO:0006810//transport gi|88196782|ref|NP_444416.2|/0/metal transporter CNNM3 isoform 1 precursor [Mus musculus] 72599 1823 1.76 2.223333333 0.337148832 Up 0.300697657 Pdia5 protein disulfide isomerase associated 5 "K09583|1|0.0|951|mmu:72599|protein disulfide isomerase family A, member 5 [EC:5.3.4.1]" GO:0044432 GO:0015036//disulfide oxidoreductase activity GO:0050896//response to stimulus;GO:0019725//cellular homeostasis;GO:0018904 gi|30794140|ref|NP_082571.1|/0/protein disulfide-isomerase A5 precursor [Mus musculus] 52245 2961 1.74 2.2 0.338416218 Up 0.300697657 Commd2 COMM domain containing 2 - - GO:0005488//binding - gi|110626003|ref|NP_780304.2|/5.53823e-99/COMM domain-containing protein 2 [Mus musculus] 382034 6528 8.07 7.12 -0.180691432 Down 0.300622438 Gse1 "genetic suppressor element 1, coiled-coil protein" "K08213|1|5e-135|486|chx:102182411|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 17" - - - gi|225543327|ref|NP_001139368.1|/0/genetic suppressor element 1 isoform 2 [Mus musculus] 72244 3219.59 12.80333333 14.21333333 0.150725474 Up 0.300613035 1600014C10Rik RIKEN cDNA 1600014C10 gene - GO:0016020//membrane;GO:0016020//membrane - - "gi|148671042|gb|EDL02989.1|/4.64391e-49/RIKEN cDNA 1600014C10, isoform CRA_a, partial [Mus musculus]" 80859 3606.16 0.896666667 1.263333333 0.494591676 Up 0.300594231 Nfkbiz "nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta" K14242|1|0.0|1263|mmu:80859|NF-kappa-B inhibitor zeta - - "GO:0006351//transcription, DNA-templated;GO:0006952//defense response;GO:0006351//transcription, DNA-templated;GO:0006952//defense response;GO:0006351//transcription, DNA-templated;GO:0006952//defense response" gi|13447398|ref|NP_085115.1|/0/NF-kappa-B inhibitor zeta isoform a [Mus musculus] 100042757 416 0.133333333 0.363333333 1.44625623 Up 0.300566024 Gm4013 predicted gene 4013 K13193|1|2e-13|76.6|cfr:102507252|RNA-binding protein 27 - - - - 71340 2744 2.903333333 2.38 -0.286748645 Down 0.300481402 Riok1 RIO kinase 1 (yeast) K07178|1|0.0|1050|mmu:71340|RIO kinase 1 [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|22208995|ref|NP_077204.2|/0/serine/threonine-protein kinase RIO1 [Mus musculus] 18759 4465 2.876666667 2.356666667 -0.287650344 Down 0.300481402 Prkci "protein kinase C, iota" K06069|1|0.0|1209|mmu:18759|atypical protein kinase C iota type [EC:2.7.11.13] GO:0043296//apical junction complex;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0043218//compact myelin;GO:0044444//cytoplasmic part GO:0004674//protein serine/threonine kinase activity;GO:0008289//lipid binding;GO:0032550;GO:0005515//protein binding;GO:0046914//transition metal ion binding GO:0043065//positive regulation of apoptotic process;GO:0006900//membrane budding;GO:0032868//response to insulin;GO:0008284//positive regulation of cell proliferation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0010828//positive regulation of glucose transport;GO:0001754//eye photoreceptor cell differentiation;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0048870//cell motility;GO:0008104//protein localization;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction;GO:0010975//regulation of neuron projection development;GO:0034330;GO:0006464//cellular protein modification process;GO:0030036//actin cytoskeleton organization;GO:0043066//negative regulation of apoptotic process;GO:0034097//response to cytokine;GO:0051130//positive regulation of cellular component organization gi|60360172|dbj|BAD90305.1|/0/mKIAA4165 protein [Mus musculus] 13058 4750 1.583333333 2.026666667 0.35614381 Up 0.300462597 Cybb "cytochrome b-245, beta polypeptide" K08008|1|0.0|1105|mmu:13058|NADPH oxidase GO:0043005//neuron projection;GO:0030666//endocytic vesicle membrane;GO:0044297//cell body;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane "GO:0000166//nucleotide binding;GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0005216//ion channel activity;GO:0046906//tetrapyrrole binding" "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0042221//response to chemical;GO:0042743//hydrogen peroxide metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006996//organelle organization;GO:0044710;GO:0034220//ion transmembrane transport;GO:0006801//superoxide metabolic process;GO:0006952//defense response;GO:0044403//symbiosis, encompassing mutualism through parasitism;GO:0031667//response to nutrient levels" gi|161333819|ref|NP_031833.3|/0/cytochrome b-245 heavy chain [Mus musculus] 66662 2355 4.133333333 4.826666667 0.223721482 Up 0.300406183 Fbxl12os "F-box and leucine-rich repeat protein 12, opposite strand" K09228|1|2e-88|194|hgl:101703224|KRAB domain-containing zinc finger protein - - - - 224045 2556 25.57333333 28.01 0.131301764 Up 0.300293354 Eif2b5 "eukaryotic translation initiation factor 2B, subunit 5 epsilon" K03240|1|0.0|1335|mmu:224045|translation initiation factor eIF-2B subunit epsilon GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0030695//GTPase regulator activity;GO:0005515//protein binding;GO:0008135//translation factor activity, RNA binding;GO:0003824//catalytic activity" GO:0006413//translational initiation;GO:0007417//central nervous system development;GO:0008585//female gonad development;GO:0032055//negative regulation of translation in response to stress;GO:0009746;GO:0008366//axon ensheathment;GO:0009725//response to hormone;GO:0021782//glial cell development gi|26986557|ref|NP_758469.1|/0/translation initiation factor eIF-2B subunit epsilon [Mus musculus] 107271 2874 12.93333333 14.33333333 0.148280007 Up 0.300283952 Yars tyrosyl-tRNA synthetase K01866|1|0.0|981|mmu:107271|tyrosyl-tRNA synthetase [EC:6.1.1.1] GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding;GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation "gi|411147387|ref|NP_598912.4|/0/tyrosine--tRNA ligase, cytoplasmic [Mus musculus]" 100504491 864 0.81 0.496666667 -0.705643983 Down 0.300265147 Dcdc2b doublecortin domain containing 2b K18598|1|2e-17|91.7|bfo:BRAFLDRAFT_123279|echinoderm microtubule-associated protein-like 6;K08805|2|1e-14|82.8|ngi:103750969|doublecortin-like kinase 1/2 [EC:2.7.11.1] - - - gi|307691167|ref|NP_001182659.1|/5.28457e-165/doublecortin domain-containing protein 2B [Mus musculus] 213027 1542 9.483333333 8.443333333 -0.167581575 Down 0.300255745 Evi5l ecotropic viral integration site 5 like K20242|1|0.0|687|mmu:213027|ecotropic viral integration site 5 protein - - - gi|568953221|ref|XP_006508812.1|/0/PREDICTED: EVI5-like protein isoform X4 [Mus musculus] 213773 2515 10.08333333 11.27666667 0.161368035 Up 0.300227538 Tbl3 transducin (beta)-like 3 K14555|1|0.0|1525|mmu:213773|U3 small nucleolar RNA-associated protein 13 GO:0030684//preribosome;GO:0031981//nuclear lumen - GO:0042254//ribosome biogenesis "gi|148690411|gb|EDL22358.1|/0/transducin (beta)-like 3, isoform CRA_b, partial [Mus musculus]" 69534 976 10.25666667 11.44333333 0.157945414 Up 0.300227538 Avpi1 arginine vasopressin-induced 1 - - - GO:0006468//protein phosphorylation;GO:0044763 "gi|149040194|gb|EDL94232.1|/1.13729e-76/arginine vasopressin-induced 1, isoform CRA_b [Rattus norvegicus]" 13983 3169 0.323333333 0.603333333 0.899933045 Up 0.300189928 Esr2 estrogen receptor 2 (beta) K08551|1|0.0|701|mmu:13983|estrogen receptor beta GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0043025//neuronal cell body;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0043025//neuronal cell body;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0043025//neuronal cell body;GO:0016020//membrane GO:0008289//lipid binding;GO:0003707//steroid hormone receptor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0008289//lipid binding;GO:0003707//steroid hormone receptor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0008289//lipid binding;GO:0003707//steroid hormone receptor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0000976//transcription regulatory region sequence-specific DNA binding GO:0002070//epithelial cell maturation;GO:0044093;GO:0030521//androgen receptor signaling pathway;GO:0002209//behavioral defense response;GO:0043410//positive regulation of MAPK cascade;GO:0002009//morphogenesis of an epithelium;GO:0016477//cell migration;GO:0044708//single-organism behavior;GO:0042981//regulation of apoptotic process;GO:0030540//female genitalia development;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0007417//central nervous system development;GO:0060548//negative regulation of cell death;GO:0006366//transcription from RNA polymerase II promoter;GO:0008585//female gonad development;GO:0009755//hormone-mediated signaling pathway;GO:0032355//response to estradiol;GO:0002070//epithelial cell maturation;GO:0044093;GO:0030521//androgen receptor signaling pathway;GO:0002209//behavioral defense response;GO:0043410//positive regulation of MAPK cascade;GO:0002009//morphogenesis of an epithelium;GO:0016477//cell migration;GO:0044708//single-organism behavior;GO:0042981//regulation of apoptotic process;GO:0030540//female genitalia development;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0007417//central nervous system development;GO:0060548//negative regulation of cell death;GO:0006366//transcription from RNA polymerase II promoter;GO:0008585//female gonad development;GO:0009755//hormone-mediated signaling pathway;GO:0032355//response to estradiol;GO:0002070//epithelial cell maturation;GO:0044093;GO:0030521//androgen receptor signaling pathway;GO:0002209//behavioral defense response;GO:0043410//positive regulation of MAPK cascade;GO:0002009//morphogenesis of an epithelium;GO:0016477//cell migration;GO:0044708//single-organism behavior;GO:0042981//regulation of apoptotic process;GO:0030540//female genitalia development;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0007417//central nervous system development;GO:0060548//negative regulation of cell death;GO:0006366//transcription from RNA polymerase II promoter;GO:0008585//female gonad development;GO:0009755//hormone-mediated signaling pathway;GO:0032355//response to estradiol gi|46877094|ref|NP_034287.3|/0/estrogen receptor beta isoform 2 [Mus musculus] 66830 4332 28.38333333 25.95666667 -0.128938904 Down 0.300124111 Nacc1 "nucleus accumbens associated 1, BEN and BTB (POZ) domain containing" K10486|1|0.0|911|mmu:66830|BTB/POZ domain-containing protein 14 GO:0044451 - "GO:0012502//induction of programmed cell death;GO:0051259//protein oligomerization;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation" gi|268837281|ref|NP_080064.3|/0/nucleus accumbens-associated protein 1 [Mus musculus] 66054 2140.87 17.52333333 19.25666667 0.13608076 Up 0.300095904 Cndp2 CNDP dipeptidase 2 (metallopeptidase M20 family) K08660|1|0.0|916|mmu:66054|cytosolic nonspecific dipeptidase [EC:3.4.13.18] GO:0044424;GO:0044424 GO:0008238//exopeptidase activity;GO:0043169//cation binding;GO:0008238//exopeptidase activity;GO:0043169//cation binding GO:0019538//protein metabolic process;GO:0019538//protein metabolic process "gi|190016263|pdb|2ZOF|A/0/Chain A, Crystal Structure Of Mouse Carnosinase Cn2 Complexed With Mn Bestatin" 227720 8195 5.383333333 4.64 -0.214374954 Down 0.300048892 Nup214 nucleoporin 214 K14317|1|0.0|2697|mmu:227720|nuclear pore complex protein Nup214 - - - gi|28972035|dbj|BAC65471.1|/0/mKIAA0023 protein [Mus musculus] 331524 2898 1.13 0.776666667 -0.540955318 Down 0.299983076 Xkrx "X-linked Kx blood group related, X-linked" K19522|1|8e-124|447|fpg:101924151|membrane transport protein XK - - - - 225608 4562 1.596666667 1.196666667 -0.416041812 Down 0.299954869 Sh3tc2 SH3 domain and tetratricopeptide repeats 2 - GO:0005768//endosome;GO:0016020//membrane - GO:0022011//myelination in peripheral nervous system gi|569003750|ref|XP_006525944.1|/0/PREDICTED: SH3 domain and tetratricopeptide repeat-containing protein 2 isoform X1 [Mus musculus] 216963 3670 55.49666667 60.13333333 0.115763812 Up 0.299926661 Git1 G protein-coupled receptor kinase-interactor 1 K05737|1|0.0|1467|mmu:216963|G protein-coupled receptor kinase interactor 1 GO:0044424;GO:0005924//cell-substrate adherens junction "GO:0046914//transition metal ion binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0051020//GTPase binding;GO:0042802//identical protein binding" GO:0007186//G-protein coupled receptor signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0032012//regulation of ARF protein signal transduction gi|51921285|ref|NP_001004144.1|/0/ARF GTPase-activating protein GIT1 [Mus musculus] 170742 1356 3.39 4.013333333 0.243515713 Up 0.299917259 Sertad3 SERTA domain containing 3 K10267|1|5e-16|88.2|ngi:103731926|F-box and WD-40 domain protein 12/13/14/15/16/17/19 GO:0043231//intracellular membrane-bounded organelle - "GO:0016049//cell growth;GO:0006351//transcription, DNA-templated" gi|18875358|ref|NP_573473.1|/5.3038e-79/SERTA domain-containing protein 3 [Mus musculus] 231912 6173 4.1 3.483333333 -0.235155373 Down 0.299917259 Katnal1 katanin p60 subunit A-like 1 K07767|1|0.0|915|mmu:231912|katanin p60 ATPase-containing subunit A1 [EC:3.6.4.3] GO:0015630//microtubule cytoskeleton "GO:0042623//ATPase activity, coupled;GO:0032550" GO:0007017//microtubule-based process;GO:0048232//male gamete generation "gi|148673904|gb|EDL05851.1|/0/katanin p60 subunit A-like 1, isoform CRA_a, partial [Mus musculus]" 104158 1966 52.75 57.37 0.121125424 Up 0.299879649 Ces1d carboxylesterase 1D K01044|1|0.0|1123|mmu:104158|carboxylesterase 1 [EC:3.1.1.1] GO:0044432 GO:0016298//lipase activity;GO:0052689//carboxylic ester hydrolase activity GO:0009062//fatty acid catabolic process;GO:0042221//response to chemical;GO:0006732;GO:0034377//plasma lipoprotein particle assembly;GO:0006639//acylglycerol metabolic process "gi|148679149|gb|EDL11096.1|/0/mCG145172, partial [Mus musculus]" 209011 1715 7.033333333 7.973333333 0.180974391 Up 0.299795028 Sirt7 sirtuin 7 K11417|1|0.0|724|mmu:209011|NAD-dependent deacetylase sirtuin 7 [EC:3.5.1.-] GO:0030874//nucleolar chromatin GO:0043169//cation binding;GO:0043168//anion binding;GO:0017136//NAD-dependent histone deacetylase activity GO:0006366//transcription from RNA polymerase II promoter;GO:0016575//histone deacetylation;GO:0010458//exit from mitosis "gi|148702831|gb|EDL34778.1|/0/sirtuin 7 (silent mating type information regulation 2, homolog) 7 (S. cerevisiae), isoform CRA_c, partial [Mus musculus]" 269233 4047.28 8.246666667 7.303333333 -0.175256016 Down 0.299795028 Fam171a1 "family with sequence similarity 171, member A1" K06476|1|2e-19|101|fpg:101913845|integrin alpha 2B;K06824|2|6e-06|56.6|bfo:BRAFLDRAFT_123314|nephronectin GO:0031224//intrinsic component of membrane - - gi|124487205|ref|NP_001074630.1|/0/protein FAM171A1 isoform 1 precursor [Mus musculus] 73545 3097 1.02 1.403333333 0.46028858 Up 0.299682199 1700094D03Rik RIKEN cDNA 1700094D03 gene - - - - "gi|148683219|gb|EDL15166.1|/6.95632e-60/mCG146184, partial [Mus musculus]" 12417 1851 16.28666667 17.99666667 0.144038353 Up 0.299559968 Cbx3 chromobox 3 K11586|1|9e-67|257|mdo:100010415|chromobox protein 3 GO:0015630//microtubule cytoskeleton;GO:0019866//organelle inner membrane;GO:0005720//nuclear heterochromatin;GO:0012505//endomembrane system;GO:0000793//condensed chromosome GO:0005515//protein binding "GO:0016568//chromatin modification;GO:0006351//transcription, DNA-templated" "gi|148666225|gb|EDK98641.1|/2.05998e-66/mCG119115, isoform CRA_b, partial [Mus musculus]" 19342 1170 12.77333333 14.15 0.147666993 Up 0.299494152 Rab4b "RAB4B, member RAS oncogene family" K07880|1|5e-118|426|rno:50866|Ras-related protein Rab-4B GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0006810//transport;GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0045184//establishment of protein localization "gi|148692254|gb|EDL24201.1|/1.35948e-117/RAB4B, member RAS oncogene family, partial [Mus musculus]" 75291 2037 0.5 0.81 0.695993813 Up 0.299484749 Zbtb3 zinc finger and BTB domain containing 3 K10490|1|0.0|885|mmu:75291|zinc finger and BTB domain-containing protein 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|15214571|gb|AAH12410.1|/0/Zbtb3 protein, partial [Mus musculus]" 228355 6041.76 2.506666667 2.016666667 -0.31379752 Down 0.299456542 Madd MAP-kinase activating death domain K18061|1|1e-19|102|mde:101889955|myotubularin-related protein 5/13;K20163|3|4e-19|100|hro:HELRODRAFT_77102|DENN domain-containing protein 4 GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424 "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005088//Ras guanyl-nucleotide exchange factor activity" GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0006915//apoptotic process;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0006915//apoptotic process "gi|148695586|gb|EDL27533.1|/0/MAP-kinase activating death domain, isoform CRA_e, partial [Mus musculus]" 109857 1178 2.53 2.036666667 -0.312927506 Down 0.299456542 Cbr3 carbonyl reductase 3 K00084|1|2e-157|557|mmu:109857|carbonyl reductase 3 [EC:1.1.1.184] GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0043168//anion binding" GO:0042374 gi|27413160|ref|NP_766635.1|/1.49783e-156/carbonyl reductase [NADPH] 3 [Mus musculus] 68521 3077 1.456666667 1.883333333 0.370617588 Up 0.299418933 Fam189b "family with sequence similarity 189, member B" - GO:0031224//intrinsic component of membrane GO:0019904//protein domain specific binding - gi|67846101|ref|NP_001014995.1|/0/protein FAM189B [Mus musculus] 14166 2534 1.446666667 1.873333333 0.372875088 Up 0.299418933 Fgf11 fibroblast growth factor 11 K04358|1|5e-127|457|mmu:14166|fibroblast growth factor - GO:0005102//receptor binding;GO:0005102//receptor binding - gi|6753844|ref|NP_034328.1|/4.60724e-126/fibroblast growth factor 11 isoform 1 [Mus musculus] 75141 2810 3.683333333 3.096666667 -0.250295868 Down 0.299390725 Rasd2 "RASD family, member 2" "K07844|1|8e-151|537|rno:171099|RASD family, member 2" GO:0016020//membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0044390//ubiquitin-like protein conjugating enzyme binding GO:0007270//neuron-neuron synaptic transmission;GO:0016567//protein ubiquitination;GO:0009154//purine ribonucleotide catabolic process;GO:0016925//protein sumoylation;GO:0044708//single-organism behavior "gi|22477556|gb|AAH36988.1|/1.81343e-168/Rasd2 protein, partial [Mus musculus]" 73834 1410 52.91666667 57.38333333 0.116909589 Up 0.299371921 Atp6v1d "ATPase, H+ transporting, lysosomal V1 subunit D" K02149|1|5e-113|410|rno:299159|V-type H+-transporting ATPase subunit D GO:0005774//vacuolar membrane GO:0005488//binding;GO:0015405 "GO:0006996//organelle organization;GO:0006818//hydrogen transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006875//cellular metal ion homeostasis;GO:0044403//symbiosis, encompassing mutualism through parasitism;GO:0015031//protein transport" gi|537155907|gb|ERE72905.1|/3.70191e-115/V-type proton ATPase subunit D-like protein [Cricetulus griseus] 317653 1281 0.476666667 0.23 -1.05134688 Down 0.29921208 Klk14 kallikrein related-peptidase 14 K09622|1|8e-127|456|mmu:317653|kallikrein 14 [EC:3.4.21.-] - - - - 56360 1774.31 11.33666667 10.17 -0.156676826 Down 0.299202678 Acot9 acyl-CoA thioesterase 9 K17361|1|0.0|889|mmu:56360|acyl-coenzyme A thioesterase 9 [EC:3.1.2.-] - - - - 69241 956 9.77 10.94333333 0.163621782 Up 0.299202678 Polr2d polymerase (RNA) II (DNA directed) polypeptide D K03012|1|1e-72|275|ssc:100737579|DNA-directed RNA polymerase II subunit RPB4 "GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0016591//DNA-directed RNA polymerase II, holoenzyme" GO:0016301//kinase activity;GO:0036094//small molecule binding;GO:0034062//RNA polymerase activity;GO:0016301//kinase activity;GO:0036094//small molecule binding;GO:0034062//RNA polymerase activity GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006397//mRNA processing;GO:0044764;GO:0006289//nucleotide-excision repair;GO:0000377;GO:0006464//cellular protein modification process;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006397//mRNA processing;GO:0044764;GO:0006289//nucleotide-excision repair;GO:0000377;GO:0006464//cellular protein modification process "gi|83754528|pdb|2C35|A/7.39815e-73/Chain A, Subunits Rpb4 And Rpb7 Of Human Rna Polymerase Ii" 243219 5838 13.72333333 12.35666667 -0.151341334 Down 0.299136861 2900026A02Rik RIKEN cDNA 2900026A02 gene - - - - - 102323 3045.72 25.31666667 27.66666667 0.128061372 Up 0.299089849 Dcun1d2 "DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae)" K17822|1|2e-125|416|mmu:102323|DCN1-like protein 1/2 - - - "gi|148690187|gb|EDL22134.1|/1.31197e-131/mCG3700, isoform CRA_e, partial [Mus musculus]" 54638 2274 6.896666667 7.823333333 0.181884197 Up 0.298995825 Ccdc22 coiled-coil domain containing 22 - - - - "gi|148701955|gb|EDL33902.1|/0/coiled-coil domain containing 22, isoform CRA_b, partial [Mus musculus]" 20930 1193.18 24.35 26.69333333 0.132557701 Up 0.298911204 Surf1 surfeit gene 1 K14998|1|3e-158|560|mmu:20930|surfeit locus 1 family protein GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity GO:0006818//hydrogen transport;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006091//generation of precursor metabolites and energy;GO:0006811//ion transport;GO:0006818//hydrogen transport;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006091//generation of precursor metabolites and energy;GO:0006811//ion transport;GO:0006818//hydrogen transport;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006091//generation of precursor metabolites and energy;GO:0006811//ion transport "gi|148676391|gb|EDL08338.1|/5.07144e-176/surfeit gene 1, isoform CRA_a [Mus musculus]" 213469 3197 1.683333333 1.273333333 -0.40271075 Down 0.298826582 Lgi3 "leucine-rich repeat LGI family, member 3" K19999|1|0.0|1027|mmu:213469|leucine-rich repeat LGI family member 3 GO:0030136//clathrin-coated vesicle;GO:0042995//cell projection - GO:0006887//exocytosis gi|21644575|ref|NP_660254.1|/0/leucine-rich repeat LGI family member 3 precursor [Mus musculus] 69956 2601 52.44333333 48.11333333 -0.124322633 Down 0.298807778 Ptcd3 pentatricopeptide repeat domain 3 K17659|1|0.0|1296|mmu:69956|pentatricopeptide repeat domain-containing protein 3 - - - "gi|148666541|gb|EDK98957.1|/0/RIKEN cDNA 2810422B04, isoform CRA_b, partial [Mus musculus]" 56198 4532 13.72666667 12.36666667 -0.150524643 Down 0.298723156 Heyl hairy/enhancer-of-split related with YRPW motif-like K09091|1|4e-157|558|mmu:56198|hairy and enhancer of split related with YRPW motif GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0003696//satellite DNA binding" GO:0003272//endocardial cushion formation;GO:0003206//cardiac chamber morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0001837//epithelial to mesenchymal transition;GO:0030521//androgen receptor signaling pathway;GO:0003177;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0007519//skeletal muscle tissue development;GO:0003281//ventricular septum development;GO:0003171//atrioventricular valve development;GO:0030182//neuron differentiation gi|31560486|ref|NP_038933.2|/3.55207e-156/hairy/enhancer-of-split related with YRPW motif-like protein [Mus musculus] 22370 1763 25.05666667 27.38666667 0.128279178 Up 0.298694949 Vtn vitronectin K06251|1|0.0|916|mmu:22370|vitronectin GO:0031012//extracellular matrix;GO:0044421 GO:0001871;GO:0005102//receptor binding;GO:0005539//glycosaminoglycan binding GO:0043062//extracellular structure organization;GO:0043393//regulation of protein binding;GO:0007160//cell-matrix adhesion;GO:0002376//immune system process;GO:0010466//negative regulation of peptidase activity;GO:0006898//receptor-mediated endocytosis;GO:0014909//smooth muscle cell migration;GO:0001934//positive regulation of protein phosphorylation;GO:0010810//regulation of cell-substrate adhesion gi|6755987|ref|NP_035837.1|/0/vitronectin precursor [Mus musculus] 14132 1738 49.97333333 54.27666667 0.11917367 Up 0.298694949 Fcgrt "Fc receptor, IgG, alpha chain transporter" "K06751|1|2e-34|149|oaa:100078585|major histocompatibility complex, class I" GO:0031224//intrinsic component of membrane;GO:0042611 GO:0019763//immunoglobulin receptor activity;GO:0019865//immunoglobulin binding GO:0038093//Fc receptor signaling pathway "gi|148690852|gb|EDL22799.1|/0/Fc receptor, IgG, alpha chain transporter, isoform CRA_a, partial [Mus musculus]" 233651 10651 3.43 2.866666667 -0.258834417 Down 0.298694949 Dchs1 dachsous 1 (Drosophila) K16507|1|0.0|5991|mmu:233651|protocadherin-16/23 - - - - 56294 4087 5.246666667 6.03 0.200756867 Up 0.298600925 Ptpn9 "protein tyrosine phosphatase, non-receptor type 9" K18038|1|0.0|1216|mmu:56294|tyrosine-protein phosphatase non-receptor type 9 [EC:3.1.3.48] - - - gi|589916575|ref|XP_006971607.1|/0/PREDICTED: tyrosine-protein phosphatase non-receptor type 9 [Peromyscus maniculatus bairdii] 16447 1924 0.033333333 0.21 2.655351829 Up 0.298600925 Ivl involucrin K04650|1|1e-10|71.2|aga:AgaP_AGAP004734|nuclear receptor co-repressor 1 GO:0044424 - GO:0009913//epidermal cell differentiation gi|156229720|gb|AAI52327.1|/7.25401e-139/Ivl protein [Mus musculus] 16467 3677 0.756666667 0.453333333 -0.739085646 Down 0.298535109 Atcay "ataxia, cerebellar, Cayman type" K18450|1|0.0|679|mmu:16467|caytaxin - - - - 68969 917 47.88 52.13666667 0.122875196 Up 0.298516304 Eif1b eukaryotic translation initiation factor 1B K03113|1|1e-50|202|gja:107118757|translation initiation factor 1 - "GO:0008135//translation factor activity, RNA binding" GO:0006413//translational initiation "gi|440909886|gb|ELR59745.1|/2.80244e-50/Eukaryotic translation initiation factor 1b, partial [Bos mutus]" 69354 3932 1.503333333 1.116666667 -0.428966338 Down 0.298403475 Slc38a4 "solute carrier family 38, member 4" "K14991|1|0.0|1010|mmu:69354|solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 4" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0046943//carboxylic acid transmembrane transporter activity GO:0046942//carboxylic acid transport;GO:0030001//metal ion transport gi|31543737|ref|NP_081328.2|/0/sodium-coupled neutral amino acid transporter 4 [Mus musculus] 629159 2432 1.506666667 1.116666667 -0.432161677 Down 0.298403475 1700008J07Rik RIKEN cDNA 1700008J07 gene - - - - gi|26349833|dbj|BAC38556.1|/3.88007e-63/unnamed protein product [Mus musculus] 215210 1278 12.29666667 13.65 0.150633663 Up 0.29838467 Tmem120a transmembrane protein 120A K14574|1|2e-65|252|spu:588956|ribosome maturation protein SDO1 GO:0031224//intrinsic component of membrane - - gi|29789387|ref|NP_766129.1|/0/transmembrane protein 120A [Mus musculus] 14534 3045 11.99666667 13.35 0.15420614 Up 0.29838467 Kat2a K(lysine) acetyltransferase 2A K06062|1|0.0|1407|mmu:14534|histone acetyltransferase [EC:2.3.1.48] GO:0070461//SAGA-type complex;GO:0005667//transcription factor complex;GO:0005819//spindle;GO:0070461//SAGA-type complex;GO:0005667//transcription factor complex;GO:0005819//spindle GO:0010485//H4 histone acetyltransferase activity;GO:0003712//transcription cofactor activity;GO:0019899//enzyme binding;GO:0010485//H4 histone acetyltransferase activity;GO:0003712//transcription cofactor activity;GO:0019899//enzyme binding "GO:0006351//transcription, DNA-templated;GO:0043967//histone H4 acetylation;GO:0014020;GO:0040007//growth;GO:0030902//hindbrain development;GO:0030900//forebrain development;GO:0006915//apoptotic process;GO:0010608//posttranscriptional regulation of gene expression;GO:0043966//histone H3 acetylation;GO:0009952//anterior/posterior pattern specification;GO:0006351//transcription, DNA-templated;GO:0043967//histone H4 acetylation;GO:0014020;GO:0040007//growth;GO:0030902//hindbrain development;GO:0030900//forebrain development;GO:0006915//apoptotic process;GO:0010608//posttranscriptional regulation of gene expression;GO:0043966//histone H3 acetylation;GO:0009952//anterior/posterior pattern specification" "gi|148670591|gb|EDL02538.1|/0/GCN5 general control of amino acid synthesis-like 2 (yeast), isoform CRA_a, partial [Mus musculus]" 66530 1714 46.54333333 50.75 0.124833285 Up 0.298375268 Ubxn6 UBX domain protein 6 K14011|1|0.0|824|mmu:66530|UBX domain-containing protein 6 GO:0043232;GO:0031981//nuclear lumen - - gi|672063974|ref|XP_006244396.2|/0/PREDICTED: UBX domain-containing protein 6 isoform X1 [Rattus norvegicus] 71865 4963.14 3.353333333 3.96 0.239904531 Up 0.298328256 Fbxo30 F-box protein 30 K10307|1|0.0|1529|mmu:71865|F-box protein 30 - GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0032446//protein modification by small protein conjugation;GO:0032446//protein modification by small protein conjugation gi|269973850|ref|NP_082244.2|/0/F-box only protein 30 [Mus musculus] 12125 4665.67 3.34 3.946666667 0.240786572 Up 0.298328256 Bcl2l11 BCL2-like 11 (apoptosis facilitator) K16341|1|3e-69|267|ngi:103750963|Bcl-2-like protein 11 GO:0043231//intracellular membrane-bounded organelle;GO:0097136//Bcl-2 family protein complex;GO:0015630//microtubule cytoskeleton;GO:0044425;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0097136//Bcl-2 family protein complex;GO:0015630//microtubule cytoskeleton;GO:0044425;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0097136//Bcl-2 family protein complex;GO:0015630//microtubule cytoskeleton;GO:0044425;GO:0044444//cytoplasmic part GO:0046983//protein dimerization activity;GO:0015631//tubulin binding;GO:0046983//protein dimerization activity;GO:0015631//tubulin binding;GO:0046983//protein dimerization activity;GO:0015631//tubulin binding GO:0007423//sensory organ development;GO:0007417//central nervous system development;GO:0035265//organ growth;GO:0070227;GO:0042476//odontogenesis;GO:0048732//gland development;GO:0008406//gonad development;GO:0048534//hematopoietic or lymphoid organ development;GO:0010822//positive regulation of mitochondrion organization;GO:0097193//intrinsic apoptotic signaling pathway;GO:0051726//regulation of cell cycle;GO:0043065//positive regulation of apoptotic process;GO:0031589//cell-substrate adhesion;GO:0012502//induction of programmed cell death;GO:0002260//lymphocyte homeostasis;GO:0048232//male gamete generation;GO:0033554//cellular response to stress;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0032461//positive regulation of protein oligomerization;GO:0048066//developmental pigmentation;GO:0007423//sensory organ development;GO:0007417//central nervous system development;GO:0035265//organ growth;GO:0070227;GO:0042476//odontogenesis;GO:0048732//gland development;GO:0008406//gonad development;GO:0048534//hematopoietic or lymphoid organ development;GO:0010822//positive regulation of mitochondrion organization;GO:0097193//intrinsic apoptotic signaling pathway;GO:0051726//regulation of cell cycle;GO:0043065//positive regulation of apoptotic process;GO:0031589//cell-substrate adhesion;GO:0012502//induction of programmed cell death;GO:0002260//lymphocyte homeostasis;GO:0048232//male gamete generation;GO:0033554//cellular response to stress;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0032461//positive regulation of protein oligomerization;GO:0048066//developmental pigmentation;GO:0007423//sensory organ development;GO:0007417//central nervous system development;GO:0035265//organ growth;GO:0070227;GO:0042476//odontogenesis;GO:0048732//gland development;GO:0008406//gonad development;GO:0048534//hematopoietic or lymphoid organ development;GO:0010822//positive regulation of mitochondrion organization;GO:0097193//intrinsic apoptotic signaling pathway;GO:0051726//regulation of cell cycle;GO:0043065//positive regulation of apoptotic process;GO:0031589//cell-substrate adhesion;GO:0012502//induction of programmed cell death;GO:0002260//lymphocyte homeostasis;GO:0048232//male gamete generation;GO:0033554//cellular response to stress;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0032461//positive regulation of protein oligomerization;GO:0048066//developmental pigmentation gi|568915153|ref|XP_006498679.1|/9.38143e-78/PREDICTED: bcl-2-like protein 11 isoform X3 [Mus musculus] 66042 1751 0.063333333 0.266666667 2.074000581 Up 0.298328256 Sostdc1 sclerostin domain containing 1 K16834|1|7e-42|174|cjo:107325058|sclerostin GO:0044421 - GO:0042476//odontogenesis;GO:0060572;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030509//BMP signaling pathway;GO:0001942//hair follicle development;GO:0010453//regulation of cell fate commitment gi|512954590|ref|XP_004839656.1|/2.29799e-120/PREDICTED: sclerostin domain-containing protein 1 [Heterocephalus glaber] 100042332 1707 1.683333333 2.136666667 0.344040969 Up 0.298196623 2810410L24Rik RIKEN cDNA 2810410L24 gene - - - - - 213993 2754 1.056666667 0.716666667 -0.560146181 Down 0.298121404 Ccdc186 coiled-coil domain containing 186 K20283|1|3e-18|97.1|aam:106489000|golgin subfamily A member 4 - - - gi|25072201|ref|NP_739563.1|/0/coiled-coil domain-containing protein 186 [Mus musculus] 100039186 379 0.153333333 0.01 -3.938599455 Down 0.298055587 Gm2087 predicted gene 2087 - - - - - 11806 988 0.01 0.153333333 3.938599455 Up 0.298055587 Apoa1 apolipoprotein A-I K08757|1|5e-131|469|mmu:11806|apolipoprotein A-I "GO:0034364//high-density lipoprotein particle;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0034385" GO:0004857//enzyme inhibitor activity;GO:0070325//lipoprotein particle receptor binding;GO:0032934//sterol binding;GO:0008047//enzyme activator activity;GO:0071813//lipoprotein particle binding;GO:0034190//apolipoprotein receptor binding;GO:0015248//sterol transporter activity GO:0006954//inflammatory response;GO:0032691//negative regulation of interleukin-1 beta production;GO:0050673//epithelial cell proliferation;GO:0043085//positive regulation of catalytic activity;GO:0015914//phospholipid transport;GO:0055092//sterol homeostasis;GO:0010872//regulation of cholesterol esterification;GO:0008203//cholesterol metabolic process;GO:0055090//acylglycerol homeostasis;GO:0002374//cytokine secretion involved in immune response;GO:0010901;GO:0007409//axonogenesis;GO:0043542//endothelial cell migration;GO:0035270//endocrine system development;GO:0046165;GO:0034377//plasma lipoprotein particle assembly;GO:0051346//negative regulation of hydrolase activity;GO:0018193//peptidyl-amino acid modification;GO:0055114//oxidation-reduction process;GO:0034645//cellular macromolecule biosynthetic process;GO:0030299//intestinal cholesterol absorption;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0032488//Cdc42 protein signal transduction;GO:0031647//regulation of protein stability;GO:0022408//negative regulation of cell-cell adhesion;GO:0006468//protein phosphorylation;GO:0009887//organ morphogenesis gi|160333304|ref|NP_033822.2|/4.06682e-130/apolipoprotein A-I preproprotein [Mus musculus] 12578 886.76 0.01 0.15 3.906890596 Up 0.298055587 Cdkn2a cyclin-dependent kinase inhibitor 2A K06621|1|2e-68|261|mmu:12578|cyclin-dependent kinase inhibitor 2A;K04685|4|1e-31|139|cfr:102517211|cyclin-dependent kinase inhibitor 2B - - - - 73894 610 0.01 0.153333333 3.938599455 Up 0.298055587 4930414N06Rik RIKEN cDNA 4930414N06 gene - - - - - 99349 1185.76 2.64 3.176666667 0.266975784 Up 0.298055587 Dnajc24 DnaJ heat shock protein family (Hsp40) member C24 K17867|1|8e-31|136|mmu:99349|diphthamide biosynthesis protein 4 - - - - 67330 686 0.01 0.15 3.906890596 Up 0.298055587 1700047M11Rik RIKEN cDNA 1700047M11 gene - - - - - 22445 1694 0.15 0.01 -3.906890596 Down 0.298055587 Xlr3a X-linked lymphocyte-regulated 3A K19528|1|9e-21|104|ssc:100523378|synaptonemal complex protein 3 - - - "gi|148694603|gb|EDL26550.1|/1.98766e-121/mCG114264, isoform CRA_b, partial [Mus musculus]" 14990 1528 0.01 0.153333333 3.938599455 Up 0.298055587 H2-M2 "histocompatibility 2, M region locus 2" "K06751|1|2e-170|601|mmu:14990|major histocompatibility complex, class I" GO:0044464 - - gi|34732740|gb|AAQ81303.1|/1.9334e-172/MHC class Ib antigen [Mus musculus] 72544 1346 2.676666667 3.22 0.266623201 Up 0.298055587 Exosc6 exosome component 6 K12587|1|4e-107|390|rno:307850|exosome complex component MTR3 - - - - 75539 684 0.153333333 0.01 -3.938599455 Down 0.298055587 1700022H01Rik RIKEN cDNA 1700022H01 gene - - - - - 12069 902 0.15 0.01 -3.906890596 Down 0.298055587 Bex2 brain expressed X-linked 2 K12465|1|6e-16|87.0|ptr:465780|nerve growth factor receptor-associated protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005488//binding GO:0006366//transcription from RNA polymerase II promoter;GO:0007405//neuroblast proliferation;GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044093;GO:0007049//cell cycle;GO:0030182//neuron differentiation gi|6753184|ref|NP_033879.1|/1.58916e-58/protein BEX2 [Mus musculus] 73683 2183 3.713333333 4.35 0.228300574 Up 0.29802738 Atg16l2 autophagy related 16-like 2 (S. cerevisiae) "K17890|1|0.0|1130|mmu:73683|autophagy-related protein 16, animal type" GO:0044424 - GO:0044248;GO:0045184//establishment of protein localization gi|162135950|ref|NP_001104581.1|/0/autophagy-related protein 16-2 [Mus musculus] 18131 7943 13.58666667 12.25 -0.149409802 Down 0.297999173 Notch3 notch 3 K02599|1|0.0|4566|mmu:18131|Notch GO:0031981//nuclear lumen;GO:0016021//integral component of membrane;GO:0031090//organelle membrane;GO:0012505//endomembrane system;GO:0044444//cytoplasmic part GO:0005515//protein binding GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0044267//cellular protein metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0007420//brain development;GO:0030182//neuron differentiation gi|6679096|ref|NP_032742.1|/0/neurogenic locus notch homolog protein 3 precursor [Mus musculus] 56045 3954.47 11.97 13.30666667 0.152726068 Up 0.297999173 Samhd1 "SAM domain and HD domain, 1" K12830|1|6e-53|212|smm:Smp_147300|splicing factor 3B subunit 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0042578//phosphoric ester hydrolase activity;GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0042578//phosphoric ester hydrolase activity;GO:0043169//cation binding;GO:0003676//nucleic acid binding GO:0031347//regulation of defense response;GO:0002252;GO:0031347//regulation of defense response;GO:0002252 gi|213418055|ref|NP_061339.3|/0/deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform 1 [Mus musculus] 227298 2559 12.44666667 13.78666667 0.147514258 Up 0.297999173 Fam134a "family with sequence similarity 134, member A" K14816|1|9e-23|111|tgu:100229493|pre-60S factor REI1 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|765099179|ref|NP_001292160.1|/0/protein FAM134A isoform 2 [Mus musculus] 117146 5191 50.56666667 46.44333333 -0.122715159 Down 0.297980368 Ube3b ubiquitin protein ligase E3B K10588|1|0.0|2019|mmu:117146|ubiquitin-protein ligase E3 B [EC:2.3.2.26] GO:0005622//intracellular GO:0003824//catalytic activity GO:0036211//protein modification process gi|68533242|ref|NP_473434.2|/0/ubiquitin-protein ligase E3B [Mus musculus] 30945 4276 5.243333333 4.52 -0.214161492 Down 0.297905149 Rnf19a ring finger protein 19A K11972|1|0.0|1377|mmu:30945|E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.27] GO:0031224//intrinsic component of membrane;GO:0043232 GO:0046914//transition metal ion binding;GO:0003824//catalytic activity - gi|7305437|ref|NP_038951.1|/0/E3 ubiquitin-protein ligase RNF19A [Mus musculus] 20687 4191 5.42 4.7 -0.205632095 Down 0.297905149 Sp3 trans-acting transcription factor 3 K09193|1|0.0|1254|mmu:20687|transcription factor Sp3 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043566//structure-specific DNA binding" "GO:0001501//skeletal system development;GO:0006351//transcription, DNA-templated;GO:0002573//myeloid leukocyte differentiation;GO:0007565//female pregnancy;GO:0030323//respiratory tube development;GO:0030218//erythrocyte differentiation;GO:0031076//embryonic camera-type eye development;GO:0030098//lymphocyte differentiation;GO:0001825//blastocyst formation;GO:0001501//skeletal system development;GO:0006351//transcription, DNA-templated;GO:0002573//myeloid leukocyte differentiation;GO:0007565//female pregnancy;GO:0030323//respiratory tube development;GO:0030218//erythrocyte differentiation;GO:0031076//embryonic camera-type eye development;GO:0030098//lymphocyte differentiation;GO:0001825//blastocyst formation" gi|65301157|ref|NP_001018052.1|/0/transcription factor Sp3 isoform 1 [Mus musculus] 19646 4407 23.57666667 25.85 0.13280452 Up 0.297858137 Rbbp4 retinoblastoma binding protein 4 K10752|1|0.0|885|ocu:100341469|histone-binding protein RBBP4 GO:0031519//PcG protein complex;GO:0031010//ISWI-type complex;GO:0070822//Sin3-type complex "GO:0042623//ATPase activity, coupled;GO:0019899//enzyme binding" "GO:0006259//DNA metabolic process;GO:0007049//cell cycle;GO:0006333//chromatin assembly or disassembly;GO:0043486//histone exchange;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation" gi|1016275|gb|AAC52275.1|/0/retinoblastoma-binding protein mRbAp48 [Mus musculus] 118446 3515 1.53 1.96 0.357322001 Up 0.297576065 Gjc3 "gap junction protein, gamma 3" "K07628|1|6e-140|501|mmu:118446|gap junction protein, epsilon 1" GO:0005921//gap junction;GO:0031224//intrinsic component of membrane;GO:0044464 GO:0042802//identical protein binding GO:0008366//axon ensheathment;GO:0050954//sensory perception of mechanical stimulus gi|46575910|ref|NP_536698.2|/5.08316e-139/gap junction gamma-3 protein [Mus musculus] 12388 5178.07 25.24 22.99333333 -0.134496282 Down 0.297557261 Ctnnd1 "catenin (cadherin associated protein), delta 1" "K05690|1|0.0|1727|rno:311163|catenin (cadherin-associated protein), delta 1" GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005913//cell-cell adherens junction;GO:0031252//cell leading edge;GO:0030425//dendrite;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005913//cell-cell adherens junction;GO:0031252//cell leading edge;GO:0030425//dendrite;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005913//cell-cell adherens junction;GO:0031252//cell leading edge;GO:0030425//dendrite;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005913//cell-cell adherens junction;GO:0031252//cell leading edge;GO:0030425//dendrite;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005913//cell-cell adherens junction;GO:0031252//cell leading edge;GO:0030425//dendrite;GO:0044444//cytoplasmic part GO:0050839//cell adhesion molecule binding;GO:0019902//phosphatase binding;GO:0019900//kinase binding;GO:0050839//cell adhesion molecule binding;GO:0019902//phosphatase binding;GO:0019900//kinase binding;GO:0050839//cell adhesion molecule binding;GO:0019902//phosphatase binding;GO:0019900//kinase binding;GO:0050839//cell adhesion molecule binding;GO:0019902//phosphatase binding;GO:0019900//kinase binding;GO:0050839//cell adhesion molecule binding;GO:0019902//phosphatase binding;GO:0019900//kinase binding "GO:0006351//transcription, DNA-templated;GO:0007155//cell adhesion;GO:0009913//epidermal cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030855//epithelial cell differentiation;GO:0007431//salivary gland development;GO:0006351//transcription, DNA-templated;GO:0007155//cell adhesion;GO:0009913//epidermal cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030855//epithelial cell differentiation;GO:0007431//salivary gland development;GO:0006351//transcription, DNA-templated;GO:0007155//cell adhesion;GO:0009913//epidermal cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030855//epithelial cell differentiation;GO:0007431//salivary gland development;GO:0006351//transcription, DNA-templated;GO:0007155//cell adhesion;GO:0009913//epidermal cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030855//epithelial cell differentiation;GO:0007431//salivary gland development;GO:0006351//transcription, DNA-templated;GO:0007155//cell adhesion;GO:0009913//epidermal cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030855//epithelial cell differentiation;GO:0007431//salivary gland development" gi|26006157|dbj|BAC41421.1|/0/mKIAA0384 protein [Mus musculus] 230582 1638 3.03 3.61 0.252681043 Up 0.297529053 Cyb5rl cytochrome b5 reductase-like K00326|1|2e-148|528|mmu:230582|cytochrome-b5 reductase [EC:1.6.2.2] - GO:0003824//catalytic activity GO:0044710 "gi|148698846|gb|EDL30793.1|/5.49681e-153/RIKEN cDNA 2810410C14, isoform CRA_c, partial [Mus musculus]" 20404 2817 1.16 0.806666667 -0.524080259 Down 0.297519651 Sh3gl2 SH3-domain GRB2-like 2 K11247|1|0.0|704|mmu:20404|endophilin-A GO:0030665//clathrin-coated vesicle membrane GO:0005515//protein binding GO:0031323//regulation of cellular metabolic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048193//Golgi vesicle transport;GO:0006897//endocytosis;GO:0006935//chemotaxis;GO:0007399//nervous system development;GO:0002478 gi|31560792|ref|NP_062408.2|/0/endophilin-A1 [Mus musculus] 269639 3317 6.976666667 7.883333333 0.176267872 Up 0.297463237 Zfp512 zinc finger protein 512 K15200|1|2e-35|154|bfo:BRAFLDRAFT_111367|general transcription factor 3C polypeptide 2;K00876|2|6e-33|145|myb:102264222|uridine kinase [EC:2.7.1.48];K10512|5|9e-10|68.9|ssc:100625241|zinc finger and BTB domain-containing protein 40 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|50511119|dbj|BAD32545.1|/0/mKIAA1805 protein [Mus musculus] 56812 2145.63 47.41666667 51.43 0.117215907 Up 0.297463237 Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 K09508|1|3e-99|365|mmu:56812|DnaJ homolog subfamily B member 2 - - - - 69554 1946 50.87333333 46.86666667 -0.118347437 Down 0.297463237 Klhdc2 kelch domain containing 2 K12562|1|1e-31|140|nve:NEMVE_v1g246594|amphiphysin;K10317|2|1e-20|104|nve:NEMVE_v1g100198|F-box protein 42;K20285|3|1e-20|103|cfa:609581|Rab9 effector protein with kelch motifs GO:0043231//intracellular membrane-bounded organelle - - gi|226246638|ref|NP_081393.2|/0/kelch domain-containing protein 2 [Mus musculus] 66616 2078 17.76 16.14333333 -0.137693079 Down 0.297350408 Snx9 sorting nexin 9 K17923|1|0.0|1157|mmu:66616|sorting nexin-9/18/33 GO:0012506//vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0009898//cytoplasmic side of plasma membrane GO:0044389//ubiquitin-like protein ligase binding;GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding GO:0043087//regulation of GTPase activity;GO:0044763;GO:0015031//protein transport;GO:0031334//positive regulation of protein complex assembly;GO:0006897//endocytosis;GO:0034622//cellular macromolecular complex assembly gi|74182179|dbj|BAE34110.1|/0/unnamed protein product [Mus musculus] 20623 4832.35 51.26666667 47.29 -0.116485956 Down 0.297341006 Snrk SNF related kinase K08802|1|0.0|1256|mmu:20623|SNF related kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding GO:0030097//hemopoiesis;GO:0006464//cellular protein modification process;GO:0042981//regulation of apoptotic process;GO:0006796//phosphate-containing compound metabolic process;GO:0030097//hemopoiesis;GO:0006464//cellular protein modification process;GO:0042981//regulation of apoptotic process;GO:0006796//phosphate-containing compound metabolic process gi|257196121|ref|NP_598502.2|/0/SNF-related serine/threonine-protein kinase [Mus musculus] 22791 2037 8.04 9.036666667 0.168595206 Up 0.297322201 Dnajc2 DnaJ heat shock protein family (Hsp40) member C2 K09522|1|0.0|1011|mmu:22791|DnaJ homolog subfamily C member 2 - - - - 66569 2484 7.91 8.913333333 0.172287365 Up 0.297322201 Gdpd1 glycerophosphodiester phosphodiesterase domain containing 1 K04371|1|8e-29|131|asn:102375250|mitogen-activated protein kinase 1/3 [EC:2.7.11.24];K19179|2|9e-10|68.6|nvi:100678544|glycerophosphoinositol glycerophosphodiesterase [EC:3.1.4.44] GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0008081//phosphoric diester hydrolase activity GO:0019400 gi|12847642|dbj|BAB27650.1|/0/unnamed protein product [Mus musculus] 104383 2406.74 2.503333333 2.02 -0.309495114 Down 0.297293994 Rcor2 REST corepressor 2 K11829|1|6e-111|404|rno:102554884|REST corepressor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|672039306|ref|XP_008758335.1|/0/PREDICTED: REST corepressor 2 isoform X2 [Rattus norvegicus] 57354 7534 2.936666667 2.42 -0.279172471 Down 0.297237579 Cramp1l "Crm, cramped-like (Drosophila)" - - - - gi|569001163|ref|XP_006524762.1|/0/PREDICTED: protein cramped-like isoform X2 [Mus musculus] 17228 1090 0.406666667 0.696666667 0.776621795 Up 0.297190568 Cma1 "chymase 1, mast cell" K01329|1|1e-134|481|mmu:17228|chymase [EC:3.4.21.39] - - - - 110157 3066 44.27 48.21666667 0.123202544 Up 0.29716236 Raf1 v-raf-leukemia viral oncogene 1 K04366|1|0.0|1274|mmu:110157|RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0044444//cytoplasmic part GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0019901//protein kinase binding;GO:0046983//protein dimerization activity;GO:0031267//small GTPase binding;GO:0043169//cation binding GO:0001934//positive regulation of protein phosphorylation;GO:0006461//protein complex assembly;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006996//organelle organization;GO:0044767//single-organism developmental process;GO:0006950//response to stress "gi|148667117|gb|EDK99533.1|/0/v-raf-leukemia viral oncogene 1, isoform CRA_a, partial [Mus musculus]" 53314 904 0.89 1.246666667 0.486198528 Up 0.297134153 Batf "basic leucine zipper transcription factor, ATF-like" K09034|1|2e-54|214|rno:299206|ATF-like basic leucine zipper transcriptional factor GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0001562//response to protozoan;GO:0042770//signal transduction in response to DNA damage;GO:0042092//type 2 immune response;GO:0002295//T-helper cell lineage commitment;GO:0001773//myeloid dendritic cell activation;GO:0002244//hematopoietic progenitor cell differentiation;GO:0002204//somatic recombination of immunoglobulin genes involved in immune response" "gi|148670929|gb|EDL02876.1|/2.86939e-92/basic leucine zipper transcription factor, ATF-like, partial [Mus musculus]" 22070 956 1117.056667 1203.51 0.107545756 Up 0.29696491 Tpt1 "tumor protein, translationally-controlled 1" K20301|1|6e-12|73.9|tsp:Tsp_05901|trafficking protein particle complex subunit 2 GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0005770//late endosome;GO:0044421 GO:0005515//protein binding GO:0051707//response to other organism;GO:0006915//apoptotic process;GO:0048232//male gamete generation;GO:0007398//ectoderm development gi|820987686|ref|XP_012362357.1|/4.18272e-102/PREDICTED: translationally-controlled tumor protein isoform X2 [Nomascus leucogenys] 68519 3931.25 25.34 23.12666667 -0.131859185 Down 0.296955508 Eml1 echinoderm microtubule associated protein like 1 K18595|1|0.0|1517|ngi:103727653|echinoderm microtubule-associated protein-like 1/2 GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0046872//metal ion binding - gi|556503435|ref|NP_001273276.1|/0/echinoderm microtubule-associated protein-like 1 isoform 4 [Mus musculus] 239647 2216 3.316666667 2.763333333 -0.263324424 Down 0.296880289 Pced1b PC-esterase domain containing 1B - - GO:0003824//catalytic activity - "gi|148672281|gb|EDL04228.1|/0/cDNA sequence BC038822, isoform CRA_a, partial [Mus musculus]" 18003 4404.46 10.47 9.34 -0.164766987 Down 0.296870886 Nedd9 "neural precursor cell expressed, developmentally down-regulated gene 9" K16832|1|0.0|1641|mmu:18003|enhancer of filamentation 1 GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle - GO:0022610;GO:0040007//growth;GO:0000087//mitotic M phase;GO:0022610;GO:0040007//growth;GO:0000087//mitotic M phase "gi|148709029|gb|EDL40975.1|/0/neural precursor cell expressed, developmentally down-regulated gene 9, isoform CRA_c, partial [Mus musculus]" 100040972 971 0.156666667 0.383333333 1.290901199 Up 0.296870886 Tceal7 transcription elongation factor A (SII)-like 7 - GO:0043231//intracellular membrane-bounded organelle - GO:0006412//translation;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity "gi|148691906|gb|EDL23853.1|/5.07273e-61/mCG16889, partial [Mus musculus]" 233899 2553 9.96 11.09 0.155041718 Up 0.296870886 Ccdc189 coiled-coil domain containing 189 K00871|1|3e-79|196|mmu:68961|phosphorylase kinase gamma subunit [EC:2.7.11.19] - - - - 74144 3868.59 25.67666667 23.47666667 -0.129230343 Down 0.296861484 Robo4 roundabout guidance receptor 4 "K06784|1|0.0|1756|mmu:74144|roundabout, axon guidance receptor 4" GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding GO:0048646//anatomical structure formation involved in morphogenesis;GO:0016477//cell migration;GO:0048869//cellular developmental process;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0016477//cell migration;GO:0048869//cellular developmental process "gi|148693480|gb|EDL25427.1|/0/roundabout homolog 4 (Drosophila), isoform CRA_a, partial [Mus musculus]" 66231 996.53 23.26333333 25.46666667 0.130552306 Up 0.296861484 Thoc7 THO complex 7 K13176|1|1e-93|345|mmu:66231|THO complex subunit 7 GO:0031981//nuclear lumen;GO:0000346//transcription export complex;GO:0031981//nuclear lumen;GO:0000346//transcription export complex GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0006396//RNA processing;GO:0006406//mRNA export from nucleus;GO:0006396//RNA processing;GO:0006406//mRNA export from nucleus gi|13384834|ref|NP_079711.1|/8.85704e-93/THO complex subunit 7 homolog isoform 1 [Mus musculus] 234374 2104 15.6 17.19666667 0.140582917 Up 0.296786265 Ddx49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 K14778|1|0.0|872|mmu:234374|ATP-dependent RNA helicase DDX49/DBP8 [EC:3.6.4.13] - "GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550" - gi|67972435|ref|NP_001020093.2|/0/probable ATP-dependent RNA helicase DDX49 [Mus musculus] 17169 3384.8 15.48 17.08333333 0.142184032 Up 0.296786265 Mark3 MAP/microtubule affinity regulating kinase 3 K08798|1|0.0|1372|mmu:17169|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] - - - - 14252 2614.34 43.20666667 47.09333333 0.124268909 Up 0.296776863 Flot2 flotillin 2 K07192|1|0.0|674|rno:83764|flotillin GO:0001669//acrosomal vesicle;GO:0005901//caveola;GO:0001669//acrosomal vesicle;GO:0005901//caveola;GO:0001669//acrosomal vesicle;GO:0005901//caveola;GO:0001669//acrosomal vesicle;GO:0005901//caveola GO:0035254//glutamate receptor binding;GO:0035254//glutamate receptor binding;GO:0035254//glutamate receptor binding;GO:0035254//glutamate receptor binding GO:0022610;GO:0009888//tissue development;GO:0022610;GO:0009888//tissue development;GO:0022610;GO:0022610 gi|564373356|ref|XP_006247014.1|/0/PREDICTED: flotillin-2 isoform X2 [Rattus norvegicus] 12042 1959 7.73 8.72 0.173859721 Up 0.296748655 Bcl10 B cell leukemia/lymphoma 10 K07368|1|3e-114|415|mmu:12042|B-cell CLL/lymphoma 10 GO:0000323//lytic vacuole;GO:0043235//receptor complex;GO:0016021//integral component of membrane;GO:0005874//microtubule GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding;GO:0008047//enzyme activator activity;GO:0019901//protein kinase binding;GO:0032182//ubiquitin-like protein binding;GO:0044389//ubiquitin-like protein ligase binding GO:0014020;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0002901;GO:0009612//response to mechanical stimulus;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0019724//B cell mediated immunity;GO:0006952//defense response;GO:0016567//protein ubiquitination;GO:0016310//phosphorylation;GO:0002274;GO:0012502//induction of programmed cell death;GO:0050852//T cell receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0051259//protein oligomerization;GO:0042110//T cell activation;GO:0051707//response to other organism gi|74207622|dbj|BAE40057.1|/1.28726e-143/unnamed protein product [Mus musculus] 24131 1978.58 871.2666667 939.0733333 0.108123475 Up 0.296739253 Ldb3 LIM domain binding 3 K19867|1|0.0|1147|mmu:24131|LIM domain-binding protein 3 GO:0031674//I band;GO:0042995//cell projection;GO:0031674//I band;GO:0031674//I band;GO:0031674//I band;GO:0031674//I band;GO:0042995//cell projection GO:0051393//alpha-actinin binding;GO:0046914//transition metal ion binding;GO:0051393//alpha-actinin binding;GO:0046914//transition metal ion binding;GO:0051393//alpha-actinin binding;GO:0046914//transition metal ion binding;GO:0051393//alpha-actinin binding;GO:0046914//transition metal ion binding;GO:0019901//protein kinase binding;GO:0051393//alpha-actinin binding;GO:0046914//transition metal ion binding;GO:0019901//protein kinase binding GO:0030239//myofibril assembly;GO:0030239//myofibril assembly;GO:0030239//myofibril assembly;GO:0030239//myofibril assembly;GO:0030239//myofibril assembly "gi|148692936|gb|EDL24883.1|/3.50189e-168/LIM domain binding 3, isoform CRA_b, partial [Mus musculus]" 18969 2405.47 5.896666667 6.72 0.188561591 Up 0.296739253 Pola2 "polymerase (DNA directed), alpha 2" K02321|1|0.0|1058|mmu:18969|DNA polymerase alpha subunit B GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0034061//DNA polymerase activity;GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding;GO:0034061//DNA polymerase activity;GO:0046983//protein dimerization activity GO:0006259//DNA metabolic process;GO:0006606//protein import into nucleus;GO:0006259//DNA metabolic process;GO:0006606//protein import into nucleus gi|31982107|ref|NP_032919.2|/0/DNA polymerase alpha subunit B isoform 1 [Mus musculus] 93701 4480 1.13 1.516666667 0.424581272 Up 0.296711046 Pcdhgb4 "protocadherin gamma subfamily B, 4" K16496|1|0.0|1645|mmu:93701|protocadherin gamma subfamily B;K16497|5|0.0|1366|aml:100466380|protocadherin gamma subfamily C GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|18087737|ref|NP_291054.1|/0/protocadherin gamma-B4 precursor [Mus musculus] 241303 4011 4.556666667 5.266666667 0.208911315 Up 0.296673436 Fam78a "family with sequence similarity 78, member A" - - - - gi|30425270|ref|NP_780720.1|/2.53568e-166/protein FAM78A [Mus musculus] 14866 911 46.86 42.99666667 -0.124132136 Down 0.296579413 Gstm5 "glutathione S-transferase, mu 5" K00799|1|1e-129|464|mmu:14866|glutathione S-transferase [EC:2.5.1.18] GO:0044424 "GO:0042802//identical protein binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups" GO:0006790//sulfur compound metabolic process gi|6754086|ref|NP_034490.1|/8.70103e-129/glutathione S-transferase Mu 5 [Mus musculus] 70093 3081 16.04666667 17.64 0.13657692 Up 0.296551205 Ube2q1 ubiquitin-conjugating enzyme E2Q family member 1 K10582|1|0.0|694|tup:102491744|ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23] - - - - 106200 2560.37 6.963333333 7.863333333 0.175362926 Up 0.296475986 Txndc11 thioredoxin domain containing 11 "K09582|1|5e-13|79.7|obi:106877201|protein disulfide-isomerase A4 [EC:5.3.4.1];K08056|2|2e-12|77.8|obi:106880182|protein disulfide isomerase family A, member 3 [EC:5.3.4.1]" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0019725//cellular homeostasis;GO:0019725//cellular homeostasis "gi|148664921|gb|EDK97337.1|/0/thioredoxin domain containing 11, isoform CRA_a, partial [Mus musculus]" 224624 2466 6.94 7.836666667 0.17530447 Up 0.296475986 Rab40c "Rab40C, member RAS oncogene family" K07928|1|4e-145|518|lve:103082305|Ras-related protein Rab-40 GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0032550 GO:0008366//axon ensheathment;GO:0035556//intracellular signal transduction;GO:0032446//protein modification by small protein conjugation;GO:0045184//establishment of protein localization gi|927108944|ref|XP_013851213.1|/3.48616e-144/PREDICTED: ras-related protein Rab-40C [Sus scrofa] 69296 1394.29 0.333333333 0.113333333 -1.556393349 Down 0.296447779 Tmigd3 transmembrane and immunoglobulin domain containing 3 K04268|1|2e-55|218|myb:102261536|adenosine A3 receptor;K06719|4|9e-10|66.6|cmk:103182456|CD300A/C/E/H antigen;K16663|5|1e-09|66.2|aam:106500027|CMRF35-like molecule 9 GO:0097060//synaptic membrane;GO:0016021//integral component of membrane;GO:0097060//synaptic membrane;GO:0016021//integral component of membrane GO:0004930//G-protein coupled receptor activity;GO:0004930//G-protein coupled receptor activity GO:0035588;GO:0051047//positive regulation of secretion;GO:0048243//norepinephrine secretion;GO:0009967//positive regulation of signal transduction;GO:0019722//calcium-mediated signaling;GO:0002441;GO:0033008;GO:0035588;GO:0051047//positive regulation of secretion;GO:0048243//norepinephrine secretion;GO:0009967//positive regulation of signal transduction;GO:0019722//calcium-mediated signaling;GO:0002441;GO:0033008 gi|110347604|ref|NP_033761.2|/9.03431e-112/adenosine receptor A3 [Mus musculus] 56398 2626 42.23333333 46.05 0.124819038 Up 0.296381962 Chp1 calcineurin-like EF hand protein 1 K17610|1|8e-105|384|ngi:103744929|calcineurin B homologous protein 1 "GO:0005856//cytoskeleton;GO:0012505//endomembrane system;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0016020//membrane" GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0019887//protein kinase regulator activity;GO:0019899//enzyme binding;GO:0016247//channel regulator activity GO:0006461//protein complex assembly;GO:0006486//protein glycosylation;GO:0032415//regulation of sodium:proton antiporter activity;GO:0006887//exocytosis;GO:0016567//protein ubiquitination;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0001933//negative regulation of protein phosphorylation;GO:0090313;GO:0030641//regulation of cellular pH;GO:0010447//response to acidic pH;GO:0000226//microtubule cytoskeleton organization;GO:0006606//protein import into nucleus;GO:0033173//calcineurin-NFAT signaling cascade;GO:0061024//membrane organization;GO:0010921//regulation of phosphatase activity;GO:0031647//regulation of protein stability "gi|71042796|pdb|2CT9|A/6.5007e-104/Chain A, The Crystal Structure Of Calcineurin B Homologous Proein 1 (Chp1)" 71710 5627 0.626666667 0.35 -0.840343334 Down 0.296381962 Lrrcc1 leucine rich repeat and coiled-coil domain containing 1 K16475|1|0.0|1834|mmu:71710|leucine-rich repeat and coiled-coil domain-containing protein 1 GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center - GO:0000087//mitotic M phase;GO:0000087//mitotic M phase;GO:0000087//mitotic M phase gi|50511097|dbj|BAD32534.1|/0/mKIAA1764 protein [Mus musculus] 18559 2844 2.7 2.203333333 -0.293271636 Down 0.296325548 Pctp phosphatidylcholine transfer protein K01866|1|1e-14|85.1|chx:102170371|tyrosyl-tRNA synthetase [EC:6.1.1.1];K08283|2|3e-10|70.5|bfo:BRAFLDRAFT_118505|collagen type IV alpha-3-binding protein - - - - 18293 6643.77 681.0733333 630.14 -0.112137754 Down 0.296269134 Ogdh oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) K00164|1|0.0|2034|mmu:18293|2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] GO:0043234//protein complex;GO:0005740//mitochondrial envelope;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043234//protein complex;GO:0005740//mitochondrial envelope;GO:0043234//protein complex;GO:0005740//mitochondrial envelope;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0005515//protein binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding;GO:0019842//vitamin binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0005515//protein binding;GO:0005515//protein binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding;GO:0005515//protein binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding;GO:0019842//vitamin binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0005515//protein binding" GO:0021536//diencephalon development;GO:0043648//dicarboxylic acid metabolic process;GO:0006007//glucose catabolic process;GO:0021543//pallium development;GO:0019674//NAD metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0021549//cerebellum development;GO:0021859//pyramidal neuron differentiation;GO:0009060//aerobic respiration;GO:0021772//olfactory bulb development;GO:0021544//subpallium development;GO:0006007//glucose catabolic process;GO:0043648//dicarboxylic acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0019674//NAD metabolic process;GO:0009060//aerobic respiration;GO:0021536//diencephalon development;GO:0043648//dicarboxylic acid metabolic process;GO:0006007//glucose catabolic process;GO:0021543//pallium development;GO:0019674//NAD metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0021549//cerebellum development;GO:0021859//pyramidal neuron differentiation;GO:0009060//aerobic respiration;GO:0021772//olfactory bulb development;GO:0021544//subpallium development;GO:0021536//diencephalon development;GO:0043648//dicarboxylic acid metabolic process;GO:0006007//glucose catabolic process;GO:0021543//pallium development;GO:0019674//NAD metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0021549//cerebellum development;GO:0021859//pyramidal neuron differentiation;GO:0009060//aerobic respiration;GO:0021772//olfactory bulb development;GO:0021544//subpallium development;GO:0006007//glucose catabolic process;GO:0043648//dicarboxylic acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0019674//NAD metabolic process;GO:0009060//aerobic respiration gi|60360580|dbj|BAD90530.1|/0/mKIAA4192 protein [Mus musculus] 56535 1767.04 9.703333333 10.82 0.15714816 Up 0.29617511 Pex3 peroxisomal biogenesis factor 3 K13336|1|0.0|677|mmu:56535|peroxin-3 GO:0032991//macromolecular complex;GO:0016021//integral component of membrane;GO:0031981//nuclear lumen;GO:0031231//intrinsic component of peroxisomal membrane;GO:0032991//macromolecular complex;GO:0016021//integral component of membrane;GO:0031981//nuclear lumen;GO:0031231//intrinsic component of peroxisomal membrane GO:0005515//protein binding;GO:0005515//protein binding GO:0006625//protein targeting to peroxisome;GO:0006625//protein targeting to peroxisome gi|9910484|ref|NP_064345.1|/0/peroxisomal biogenesis factor 3 isoform 1 [Mus musculus] 399603 5563 1.86 1.44 -0.36923381 Down 0.296043477 Fam84b "family with sequence similarity 84, member B" K10461|1|3e-07|61.2|bfo:BRAFLDRAFT_119296|kelch-like protein 24/35;K16817|2|5e-06|57.4|xma:102230685|HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4] GO:0044424;GO:0016020//membrane GO:0005488//binding - gi|242397444|ref|NP_001156398.1|/2.2033e-155/protein FAM84B [Mus musculus] 70365 970 0.01 0.146666667 3.874469118 Up 0.296024672 Speer5-ps1 "spermatogenesis associated glutamate (E)-rich protein 5, pseudogene 1" - - - - - 632778 910 0.01 0.146666667 3.874469118 Up 0.296024672 Erich4 glutamate rich 4 - - - - gi|258558878|gb|ACV81747.1|/1.60915e-58/kidney specific expressed protein 1 [Mus musculus] 629820 401 0.146666667 0.01 -3.874469118 Down 0.296024672 Gm7008 predicted gene 7008 - - - - - 56636 947 0.01 0.146666667 3.874469118 Up 0.296024672 Fgf21 fibroblast growth factor 21 K04358|1|2e-107|390|mmu:56636|fibroblast growth factor - GO:0070851//growth factor receptor binding GO:0043410//positive regulation of MAPK cascade;GO:0010984;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010870//positive regulation of receptor biosynthetic process;GO:0010828//positive regulation of glucose transport;GO:0008283//cell proliferation gi|9910218|ref|NP_064397.1|/1.71505e-106/fibroblast growth factor 21 precursor [Mus musculus] 100043580 713 0.146666667 0.01 -3.874469118 Down 0.296024672 Gm4532 predicted gene 4532 - - - - gi|148685570|gb|EDL17517.1|/1.52003e-30/mCG147589 [Mus musculus] 666329 1743 0.146666667 0.01 -3.874469118 Down 0.296024672 Gm3317 predicted gene 3317 "K03844|1|3e-16|89.4|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - - 53861 2616 8.666666667 7.686666667 -0.17311911 Down 0.29594005 Zranb2 "zinc finger, RAN-binding domain containing 2" K13098|1|4e-06|56.6|xma:102220690|RNA-binding protein FUS;K14651|2|8e-06|55.5|dya:Dyak_GE24196|transcription initiation factor TFIID subunit 15 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding GO:0006396//RNA processing gi|116283961|gb|AAH51187.1|/3.68799e-83/Zranb2 protein [Mus musculus] 26891 1771 42.87 46.59 0.120051913 Up 0.295864831 Cops4 COP9 signalosome subunit 4 K12178|1|0.0|765|mmu:26891|COP9 signalosome complex subunit 4 - - - - 14464 3302 0.096666667 0.306666667 1.665580961 Up 0.295855429 Gata5 GATA binding protein 5 K17896|1|0.0|665|mmu:14464|GATA-binding protein 5 GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding" GO:0071363//cellular response to growth factor stimulus;GO:0002065;GO:0006366//transcription from RNA polymerase II promoter gi|181337117|ref|NP_032119.2|/0/transcription factor GATA-5 [Mus musculus] 414069 2139.04 6.493333333 5.68 -0.193068342 Down 0.2957426 BC024978 cDNA sequence BC024978 - - - - gi|345197250|ref|NP_001230817.1|/1.72719e-176/UPF0692 protein C19orf54 homolog isoform 1 [Mus musculus] 109229 1946.07 5.746666667 6.556666667 0.190237183 Up 0.2957426 Fam118b "family with sequence similarity 118, member B" - - - - gi|30425122|ref|NP_780620.1|/9.79933e-145/protein FAM118B isoform 2 [Mus musculus] 224648 8567 2.086666667 1.646666667 -0.341651615 Down 0.295733198 Uhrf1bp1 UHRF1 (ICBP90) binding protein 1 K10737|1|2e-14|86.3|ame:412034|DNA helicase MCM8 [EC:3.6.4.12] - - - gi|60359998|dbj|BAD90218.1|/0/mKIAA4127 protein [Mus musculus] 76501 1175 15.16666667 16.73 0.141533401 Up 0.295648576 Commd9 COMM domain containing 9 - - - - gi|21313224|ref|NP_083911.1|/8.0583e-94/COMM domain-containing protein 9 [Mus musculus] 665858 1366 1.756666667 2.21 0.331205908 Up 0.295639174 Gm7827 predicted gene 7827 K17299|1|2e-53|212|mmu:626415|POTE ankyrin domain family protein - - - - 22130 4170 2.186666667 1.736666667 -0.332412442 Down 0.295639174 Ttf1 "transcription termination factor, RNA polymerase I" K15225|1|0.0|1397|mmu:22130|transcription termination factor 1 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0016568//chromatin modification;GO:0006260//DNA replication;GO:0006360//transcription from RNA polymerase I promoter gi|568913288|ref|XP_006497914.1|/0/PREDICTED: transcription termination factor 1 isoform X2 [Mus musculus] 327942 1657 1.713333333 2.16 0.334225454 Up 0.295639174 Pigl "phosphatidylinositol glycan anchor biosynthesis, class L" K03434|1|8e-142|506|mmu:327942|N-acetylglucosaminylphosphatidylinositol deacetylase [EC:3.5.1.89] GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane GO:0003824//catalytic activity GO:0006497//protein lipidation gi|88014552|ref|NP_001034625.1|/6.41463e-141/N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase [Mus musculus] 78889 2475.75 4.53 5.226666667 0.206380103 Up 0.295639174 Wsb1 WD repeat and SOCS box-containing 1 K10341|1|1e-106|390|mmu:78889|WD repeat and SOCS box-containing protein 1 GO:0044464;GO:0044464 GO:0005488//binding GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation;GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation gi|5410334|gb|AAD43037.1|/3.46963e-106/WSB-1 isoform [Homo sapiens] 216864 1550 4.556666667 5.256666667 0.206169417 Up 0.295639174 Mgl2 macrophage galactose N-acetyl-galactosamine specific lectin 2 K06721|1|6e-143|509|mmu:17312|C-type lectin domain family 10 member A GO:0031224//intrinsic component of membrane GO:0005488//binding - gi|21553093|ref|NP_660119.1|/0/macrophage galactose N-acetyl-galactosamine specific lectin 2 [Mus musculus] 71228 7878 2.17 1.723333333 -0.332493263 Down 0.295639174 Dlg5 "discs, large homolog 5 (Drosophila)" K12076|1|2e-43|182|shr:100924037|disks large protein 1;K05701|4|4e-43|181|bfo:BRAFLDRAFT_93411|tight junction protein 1 - - - gi|254588085|ref|NP_082002.1|/0/disks large homolog 5 isoform 2 [Mus musculus] 19730 3640.03 6.803333333 7.696666667 0.177991991 Up 0.295629772 Ralgds ral guanine nucleotide dissociation stimulator K08732|1|0.0|1397|mmu:19730|ral guanine nucleotide dissociation stimulator GO:0044464;GO:0044464;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005488//binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0007264//small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction gi|37360320|dbj|BAC98138.1|/0/mKIAA1308 protein [Mus musculus] 67803 2950 4.986666667 5.733333333 0.20129839 Up 0.295573357 Limd2 LIM domain containing 2 K19947|1|7e-11|72.4|aqu:105311991|protein-methionine sulfoxide oxidase MICAL [EC:1.14.13.-] - GO:0046914//transition metal ion binding - gi|625199709|ref|XP_003503024.2|/2.76424e-66/PREDICTED: LIM domain-containing protein 2 [Cricetulus griseus] 20591 11030 5.876666667 5.123333333 -0.19791531 Down 0.295573357 Kdm5c lysine (K)-specific demethylase 5C K11446|1|0.0|2762|mmu:20591|histone demethylase JARID1 [EC:1.14.11.-] - - - gi|165905607|ref|NP_038696.2|/0/lysine-specific demethylase 5C [Mus musculus] 67755 1764 22.4 24.51 0.129871752 Up 0.295404114 Ddx47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 K14777|1|0.0|787|mmu:67755|ATP-dependent RNA helicase DDX47/RRP3 [EC:3.6.4.13] GO:0031981//nuclear lumen "GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled" GO:0012501//programmed cell death;GO:0006396//RNA processing;GO:0042254//ribosome biogenesis gi|564349355|ref|XP_006237580.1|/0/PREDICTED: probable ATP-dependent RNA helicase DDX47 isoform X1 [Rattus norvegicus] 70316 800 386.9333333 416.4866667 0.106185291 Up 0.295404114 Ndufab1 "NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1" K03955|1|1e-66|254|mmu:70316|NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1 GO:0005746//mitochondrial respiratory chain - GO:0006631//fatty acid metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0018065//protein-cofactor linkage;GO:0051234//establishment of localization "gi|27754007|ref|NP_082453.2|/1.0778e-65/acyl carrier protein, mitochondrial precursor [Mus musculus]" 66853 2635.23 384.9266667 414.0233333 0.105128456 Up 0.295394712 Pnpla2 patatin-like phospholipase domain containing 2 K16816|1|0.0|762|rno:361676|patatin-like phospholipase domain-containing protein 2 [EC:3.1.1.3] GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0016298//lipase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0005488//binding;GO:0016298//lipase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0005488//binding;GO:0016298//lipase activity;GO:0052689//carboxylic ester hydrolase activity GO:0010896//regulation of triglyceride catabolic process;GO:0010888//negative regulation of lipid storage;GO:0010896//regulation of triglyceride catabolic process;GO:0010888//negative regulation of lipid storage;GO:0010896//regulation of triglyceride catabolic process;GO:0010888//negative regulation of lipid storage gi|254826780|ref|NP_001157161.1|/0/patatin-like phospholipase domain-containing protein 2 isoform 1 [Mus musculus] 50785 3732 15.66 17.21 0.136162885 Up 0.295366505 Hs6st1 heparan sulfate 6-O-sulfotransferase 1 K02514|1|0.0|719|mmu:50785|heparan sulfate 6-O-sulfotransferase HS6ST1 [EC:2.8.2.-] GO:0031224//intrinsic component of membrane "GO:0016782//transferase activity, transferring sulfur-containing groups" GO:0030166//proteoglycan biosynthetic process;GO:0048568//embryonic organ development;GO:0030324//lung development gi|225690608|ref|NP_056633.2|/0/heparan-sulfate 6-O-sulfotransferase 1 [Mus musculus] 53422 1564 17.24 15.69333333 -0.135607955 Down 0.295366505 Ybx2 Y box protein 2 K09277|1|2e-81|305|mmu:53422|Y-box-binding protein 2 GO:0030529//intracellular ribonucleoprotein complex GO:0003729//mRNA binding GO:0006412//translation;GO:0044092//negative regulation of molecular function;GO:0007292//female gamete generation;GO:0043488//regulation of mRNA stability;GO:0007281//germ cell development gi|742155949|ref|XP_010845801.1|/6.23186e-85/PREDICTED: Y-box-binding protein 2 [Bison bison bison] 270084 2800 0.58 0.313333333 -0.888354644 Down 0.295338298 Lpcat2 lysophosphatidylcholine acyltransferase 2 K13510|1|0.0|1040|mmu:270084|lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67] GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0012505//endomembrane system;GO:0044431//Golgi apparatus part GO:0046872//metal ion binding;GO:0016413//O-acetyltransferase activity GO:0044763;GO:0046470//phosphatidylcholine metabolic process;GO:0046165 gi|27370522|ref|NP_766602.1|/0/lysophosphatidylcholine acyltransferase 2 [Mus musculus] 21412 1240 2.806666667 3.35 0.255303363 Up 0.295328895 Tcf21 transcription factor 21 K09072|1|2e-41|172|lcm:102362750|musculin (activated B-cell factor-1) GO:0043231//intracellular membrane-bounded organelle "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0044212//transcription regulatory region DNA binding;GO:0035258//steroid hormone receptor binding;GO:0019899//enzyme binding;GO:0008134//transcription factor binding" GO:0030324//lung development;GO:0006366//transcription from RNA polymerase II promoter;GO:0003006//developmental process involved in reproduction;GO:0016575//histone deacetylation;GO:0030521//androgen receptor signaling pathway;GO:0048534//hematopoietic or lymphoid organ development;GO:0072075//metanephric mesenchyme development;GO:0007519//skeletal muscle tissue development;GO:0009887//organ morphogenesis;GO:0030154//cell differentiation;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048546//digestive tract morphogenesis;GO:0072104//glomerular capillary formation "gi|148672817|gb|EDL04764.1|/6.26023e-108/transcription factor 21, isoform CRA_b, partial [Mus musculus]" 14325 986 369.4566667 397.5333333 0.105670675 Up 0.295319493 Ftl1 ferritin light polypeptide 1 K13625|1|1e-100|368|mmu:14325|ferritin light chain GO:0044424 GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0003824//catalytic activity GO:0000041//transition metal ion transport;GO:0010038//response to metal ion;GO:0006875//cellular metal ion homeostasis gi|114326466|ref|NP_034370.2|/9.71768e-100/ferritin light chain 1 [Mus musculus] 22290 5164 1.966666667 1.54 -0.352822103 Down 0.295263079 Uty "ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome" K11447|1|0.0|2242|mmu:22290|histone demethylase [EC:1.14.11.-] - - - - 239114 1232 2.88 2.366666667 -0.283212288 Down 0.295253676 Il17d interleukin 17D K05492|1|9e-97|356|mmu:239114|interleukin 17D GO:0044421 GO:0005102//receptor binding GO:0006952//defense response gi|148277104|ref|NP_665836.2|/7.09919e-96/interleukin-17D precursor [Mus musculus] 16001 11978 3.616666667 4.233333333 0.227133454 Up 0.295197262 Igf1r insulin-like growth factor I receptor K05087|1|0.0|2586|mmu:16001|insulin-like growth factor 1 receptor [EC:2.7.10.1] GO:0031224//intrinsic component of membrane;GO:0044459;GO:0042995//cell projection;GO:0043227//membrane-bounded organelle GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0017046//peptide hormone binding;GO:0032550;GO:0005520//insulin-like growth factor binding GO:0031016//pancreas development;GO:0048017//inositol lipid-mediated signaling;GO:0048732//gland development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0014070//response to organic cyclic compound;GO:0007163//establishment or maintenance of cell polarity;GO:0002009//morphogenesis of an epithelium;GO:0016477//cell migration;GO:0007254//JNK cascade;GO:0006469//negative regulation of protein kinase activity;GO:0000910//cytokinesis;GO:0010893//positive regulation of steroid biosynthetic process;GO:0006260//DNA replication;GO:0002376//immune system process;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007417//central nervous system development;GO:0051259//protein oligomerization;GO:0043066//negative regulation of apoptotic process;GO:0030030//cell projection organization gi|112983656|ref|NP_034643.2|/0/insulin-like growth factor 1 receptor precursor [Mus musculus] 59057 3143 3.98 4.626666667 0.217204731 Up 0.295197262 Zfp24 zinc finger protein 24 K09230|1|0.0|760|mmu:59057|SCAN domain-containing zinc finger protein - - - - 67797 1789 4.046666667 4.7 0.215926741 Up 0.295197262 Snrnp48 small nuclear ribonucleoprotein 48 (U11/U12) K13156|1|8e-150|533|mmu:67797|U11/U12 small nuclear ribonucleoprotein 48 kDa protein GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen - - "gi|148708989|gb|EDL40935.1|/7.06002e-149/RIKEN cDNA 6530403A03, partial [Mus musculus]" 11858 684 3.893333333 3.3 -0.238539844 Down 0.295065629 Rnd2 Rho family GTPase 2 K07858|1|3e-117|422|mmu:11858|Rho family GTPase 2 GO:0005768//endosome;GO:0001669//acrosomal vesicle GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process gi|6753116|ref|NP_033838.1|/2.15273e-116/rho-related GTP-binding protein RhoN precursor [Mus musculus] 19072 2768 22.8 24.89 0.126532406 Up 0.295065629 Prep prolyl endopeptidase K01322|1|0.0|1488|mmu:19072|prolyl oligopeptidase [EC:3.4.21.26] GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle GO:0033218//amide binding;GO:0004175//endopeptidase activity;GO:0008236//serine-type peptidase activity GO:0019538//protein metabolic process gi|6755152|ref|NP_035286.1|/0/prolyl endopeptidase [Mus musculus] 330812 9685 2.113333333 2.596666667 0.297140488 Up 0.295065629 Rnf150 ring finger protein 150 K15701|1|3e-96|357|cmk:103188225|E3 ubiquitin-protein ligase RNF130 [EC:2.3.2.27] - - - gi|674069230|ref|XP_008841674.1|/0/PREDICTED: LOW QUALITY PROTEIN: RING finger protein 150 [Nannospalax galili] 20520 3119 11.70666667 12.96333333 0.14710639 Up 0.295028019 Slc22a5 "solute carrier family 22 (organic cation transporter), member 5" "K08202|1|0.0|1092|mmu:20520|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 4/5" GO:0031224//intrinsic component of membrane;GO:0005903//brush border;GO:0044459 GO:0032550;GO:0015101//organic cation transmembrane transporter activity;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0019904//protein domain specific binding;GO:0015291//secondary active transmembrane transporter activity;GO:0019534//toxin transporter activity GO:0032846;GO:0006577//amino-acid betaine metabolic process;GO:0030001//metal ion transport;GO:0015695//organic cation transport;GO:0003006//developmental process involved in reproduction;GO:0007507//heart development;GO:0015893//drug transport;GO:0051701//interaction with host;GO:0006996//organelle organization;GO:0044708//single-organism behavior gi|6755540|ref|NP_035526.1|/0/solute carrier family 22 member 5 [Mus musculus] 67311 1392 1.11 0.77 -0.527629326 Down 0.295028019 Nanp N-acetylneuraminic acid phosphatase K01097|1|5e-141|503|mmu:67311|N-acylneuraminate-9-phosphatase [EC:3.1.3.29] - GO:0016791//phosphatase activity GO:0006044//N-acetylglucosamine metabolic process;GO:0006054//N-acetylneuraminate metabolic process;GO:0044238//primary metabolic process gi|13385586|ref|NP_080362.1|/4.26194e-140/N-acylneuraminate-9-phosphatase [Mus musculus] 68728 3934 341.4366667 316.8766667 -0.107696567 Down 0.295018617 Trp53inp2 transformation related protein 53 inducible nuclear protein 2 K15310|1|4e-16|90.5|cjo:107310375|tumor protein p53-inducible nuclear protein 1 - - - - 74617 2087 9.133333333 10.23 0.163592753 Up 0.29499041 Scpep1 serine carboxypeptidase 1 K09646|1|0.0|863|mmu:74617|serine carboxypeptidase 1 [EC:3.4.16.-] GO:0044444//cytoplasmic part GO:0004180//carboxypeptidase activity GO:0019538//protein metabolic process;GO:0001523//retinoid metabolic process gi|253970508|ref|NP_083299.3|/0/retinoid-inducible serine carboxypeptidase precursor [Mus musculus] 66606 1927.45 9.44 10.53666667 0.15855977 Up 0.29499041 Lrrc57 leucine rich repeat containing 57 K19613|1|5e-21|105|hmg:100198779|leucine-rich repeat protein SHOC2 - - - "gi|148696062|gb|EDL28009.1|/1.26091e-149/leucine rich repeat containing 57, isoform CRA_d, partial [Mus musculus]" 654362 525 1.38 1.013333333 -0.445559444 Down 0.294736545 Dear1 dual endothelin 1/angiotensin II receptor 1 K10260|1|4e-19|95.9|lcm:102363147|F-box and WD-40 domain protein 7 GO:0031981//nuclear lumen;GO:0031461//cullin-RING ubiquitin ligase complex GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0008528//G-protein coupled peptide receptor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0019838//growth factor binding GO:0006914//autophagy;GO:0050680//negative regulation of epithelial cell proliferation;GO:0021543//pallium development;GO:0007059//chromosome segregation;GO:0008104//protein localization;GO:0031398//positive regulation of protein ubiquitination;GO:0043410//positive regulation of MAPK cascade;GO:0009411//response to UV;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0007219//Notch signaling pathway;GO:0044708//single-organism behavior;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0019915//lipid storage;GO:0048878//chemical homeostasis;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0009968//negative regulation of signal transduction;GO:0033554//cellular response to stress;GO:0010866//regulation of triglyceride biosynthetic process;GO:0030323//respiratory tube development;GO:0031647//regulation of protein stability;GO:0010948//negative regulation of cell cycle process gi|154146214|ref|NP_001035551.2|/5.9777e-48/dual endothelin 1/angiotensin II receptor 1 homolog precursor [Mus musculus] 330323 3276.75 0.996666667 1.363333333 0.451955359 Up 0.294736545 Fam188b "family with sequence similarity 188, member B" K08742|1|2e-15|87.0|fpg:101913080|E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27] - - - gi|218505820|ref|NP_808551.2|/0/protein FAM188B isoform 2 [Mus musculus] 100504501 936 0.716666667 0.426666667 -0.74819285 Down 0.294727143 Gm20257 caspase 8 pseudogene K04398|1|8e-17|90.1|mmu:12370|caspase 8 [EC:3.4.22.61] - - - - 70874 1576 0.263333333 0.52 0.981621471 Up 0.294698936 4921513I03Rik RIKEN cDNA 4921513I03 gene - GO:0016020//membrane;GO:0042995//cell projection GO:0005488//binding GO:0001754//eye photoreceptor cell differentiation gi|148692459|gb|EDL24406.1|/2.41515e-49/mCG140906 [Mus musculus] 666737 669 0.456666667 0.216666667 -1.07566427 Down 0.294670728 4632427E13Rik RIKEN cDNA 4632427E13 gene - - - - - 16535 3052 21.50333333 23.56 0.131779223 Up 0.294661326 Kcnq1 "potassium voltage-gated channel, subfamily Q, member 1" K04926|1|0.0|1251|mmu:16535|potassium voltage-gated channel KQT-like subfamily member 1 - - - gi|568952646|ref|XP_006508551.1|/0/PREDICTED: potassium voltage-gated channel subfamily KQT member 1 isoform X1 [Mus musculus] 14050 5171 8.6 7.64 -0.170764022 Down 0.294492083 Eya3 EYA transcriptional coactivator and phosphatase 3 K17621|1|0.0|653|mmu:14050|eyes absent homolog 3 [EC:3.1.3.48] - - - - 380713 2884 7.63 8.586666667 0.170415131 Up 0.294492083 Scarf1 "scavenger receptor class F, member 1" K06709|1|3e-70|269|crg:105346814|jumonji domain-containing protein 2 [EC:1.14.11.-];K02258|5|4e-63|246|hmg:100209451|cytochrome c oxidase assembly protein subunit 11 GO:0031224//intrinsic component of membrane GO:0071813//lipoprotein particle binding;GO:0038024//cargo receptor activity GO:0022610;GO:0031103//axon regeneration;GO:0042551//neuron maturation;GO:0010975//regulation of neuron projection development gi|60359842|dbj|BAD90140.1|/0/mKIAA0149 protein [Mus musculus] 13560 2660.84 7.86 8.816666667 0.165704004 Up 0.294492083 E4f1 E4F transcription factor 1 K09193|1|0.0|640|ocu:100352838|transcription factor Sp3 GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0044212//transcription regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0044212//transcription regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0044212//transcription regulatory region DNA binding GO:0006259//DNA metabolic process;GO:0007275//multicellular organism development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007346//regulation of mitotic cell cycle;GO:0006259//DNA metabolic process;GO:0007275//multicellular organism development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007346//regulation of mitotic cell cycle;GO:0006259//DNA metabolic process;GO:0034645//cellular macromolecule biosynthetic process;GO:0007275//multicellular organism development;GO:0007346//regulation of mitotic cell cycle "gi|148690376|gb|EDL22323.1|/0/E4F transcription factor 1, isoform CRA_a, partial [Mus musculus]" 106489 1048 7.603333333 8.563333333 0.171540444 Up 0.294492083 Sft2d1 SFT2 domain containing 1 K10184|1|3e-29|131|fch:102055408|T-box protein 19 GO:0031224//intrinsic component of membrane - GO:0006810//transport;GO:0045184//establishment of protein localization gi|88853575|ref|NP_598875.2|/5.1717e-86/vesicle transport protein SFT2A [Mus musculus] 215467 1021 0.483333333 0.78 0.69045563 Up 0.294463876 Gm4791 predicted gene 4791 - - - - "gi|148693744|gb|EDL25691.1|/8.27293e-65/mCG145413, partial [Mus musculus]" 21849 3255 22.23666667 24.28333333 0.127025931 Up 0.294398059 Trim28 tripartite motif-containing 28 K08882|1|0.0|1340|mmu:21849|tripartite motif-containing protein 28 [EC:2.3.2.27] GO:0000790//nuclear chromatin GO:0046914//transition metal ion binding;GO:0016301//kinase activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0019787//ubiquitin-like protein transferase activity GO:0003401//axis elongation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006461//protein complex assembly;GO:0001892//embryonic placenta development;GO:0006468//protein phosphorylation;GO:0000904//cell morphogenesis involved in differentiation;GO:0032446//protein modification by small protein conjugation;GO:0006281//DNA repair gi|148706135|gb|EDL38082.1|/0/tripartite motif protein 28 [Mus musculus] 380930 1082 0.973333333 0.653333333 -0.575114715 Down 0.294351047 9330188P03Rik RIKEN cDNA 9330188P03 gene - - - - gi|148668190|gb|EDL00520.1|/1.01377e-15/mCG1042498 [Mus musculus] 381101 1106 1.03 0.696666667 -0.564103896 Down 0.294313438 Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 - GO:0031981//nuclear lumen "GO:0016763//transferase activity, transferring pentosyl groups;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0042802//identical protein binding" GO:0009125;GO:0016049//cell growth gi|110625744|ref|NP_997044.2|/1.63971e-93/2'-deoxynucleoside 5'-phosphate N-hydrolase 1 [Mus musculus] 68966 1229 14.92333333 16.44 0.139640481 Up 0.294313438 Ngdn "neuroguidin, EIF4E binding protein" K14765|1|5e-131|469|mmu:68966|U3 small nucleolar ribonucleoprotein protein LCP5 GO:0044424 - GO:0006412//translation gi|58037133|ref|NP_081166.1|/4.38902e-130/neuroguidin [Mus musculus] 15903 964 40.35666667 43.78333333 0.117574777 Up 0.294275828 Id3 inhibitor of DNA binding 3 K17694|1|5e-51|203|mmu:15903|DNA-binding protein inhibitor ID3 GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0008134//transcription factor binding GO:0048568//embryonic organ development;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001822//kidney development;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0044092//negative regulation of molecular function;GO:0009887//organ morphogenesis;GO:0006950//response to stress;GO:0007399//nervous system development;GO:0006260//DNA replication;GO:0007049//cell cycle gi|6680341|ref|NP_032347.1|/3.98418e-50/DNA-binding protein inhibitor ID-3 [Mus musculus] 227334 5316 3.116666667 2.593333333 -0.26519621 Down 0.294238219 Usp40 ubiquitin specific peptidase 40 K11869|1|0.0|2454|mmu:227334|ubiquitin carboxyl-terminal hydrolase 40 [EC:3.4.19.12] - "GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process gi|310688895|ref|NP_001185502.1|/0/ubiquitin carboxyl-terminal hydrolase 40 isoform 1 [Mus musculus] 66595 2531.92 1.916666667 1.493333333 -0.360063224 Down 0.294228816 Aste1 asteroid homolog 1 (Drosophila) K01537|1|2e-08|64.3|cjc:100411487|Ca2+-transporting ATPase [EC:3.6.3.8] - - - - 21357 1806 21.30666667 23.34666667 0.131911676 Up 0.294210012 Tarbp2 "TARBP2, RISC loading complex RNA binding subunit" K18420|1|9e-176|619|mmu:21357|RISC-loading complex subunit TARBP2 GO:0043231//intracellular membrane-bounded organelle;GO:0031332//RNAi effector complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0031332//RNAi effector complex;GO:0044444//cytoplasmic part GO:0042802//identical protein binding;GO:0003723//RNA binding;GO:0042802//identical protein binding;GO:0003723//RNA binding GO:0016246//RNA interference;GO:0006412//translation;GO:0019079//viral genome replication;GO:0050687//negative regulation of defense response to virus;GO:0019083//viral transcription;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0016246//RNA interference;GO:0006412//translation;GO:0019079//viral genome replication;GO:0050687//negative regulation of defense response to virus;GO:0019083//viral transcription;GO:0035196//production of miRNAs involved in gene silencing by miRNA gi|359385734|ref|NP_001240724.1|/6.15698e-135/RISC-loading complex subunit TARBP2 isoform 2 [Mus musculus] 74252 2955 12.89333333 11.65 -0.146295339 Down 0.294153597 Armc1 armadillo repeat containing 1 K17306|1|3e-151|538|mmu:74252|armadillo repeat-containing protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding GO:0006812//cation transport gi|21312676|ref|NP_083116.1|/2.36627e-150/armadillo repeat-containing protein 1 [Mus musculus] 74205 3914.82 0.936666667 1.296666667 0.469200025 Up 0.294115988 Acsl3 acyl-CoA synthetase long-chain family member 3 K01897|1|0.0|1416|mmu:74205|long-chain acyl-CoA synthetase [EC:6.2.1.3] GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0044439;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0044439;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0044439 GO:0032550;GO:0015645//fatty acid ligase activity;GO:0019900//kinase binding;GO:0032550;GO:0015645//fatty acid ligase activity;GO:0019900//kinase binding;GO:0032550;GO:0015645//fatty acid ligase activity;GO:0019900//kinase binding GO:0034377//plasma lipoprotein particle assembly;GO:0007417//central nervous system development;GO:0042996//regulation of Golgi to plasma membrane protein transport;GO:0015909//long-chain fatty acid transport;GO:0010033//response to organic substance;GO:0006631//fatty acid metabolic process;GO:0033240;GO:0046903//secretion;GO:0031667//response to nutrient levels;GO:0034377//plasma lipoprotein particle assembly;GO:0007417//central nervous system development;GO:0042996//regulation of Golgi to plasma membrane protein transport;GO:0015909//long-chain fatty acid transport;GO:0010033//response to organic substance;GO:0006631//fatty acid metabolic process;GO:0033240;GO:0046903//secretion;GO:0031667//response to nutrient levels;GO:0034377//plasma lipoprotein particle assembly;GO:0007417//central nervous system development;GO:0042996//regulation of Golgi to plasma membrane protein transport;GO:0015909//long-chain fatty acid transport;GO:0010033//response to organic substance;GO:0006631//fatty acid metabolic process;GO:0033240;GO:0046903//secretion;GO:0031667//response to nutrient levels gi|75992920|ref|NP_083093.2|/0/long-chain-fatty-acid--CoA ligase 3 isoform a [Mus musculus] 208618 6792.72 6.466666667 7.336666667 0.182102493 Up 0.294078378 Etl4 enhancer trap locus 4 K19930|1|0.0|1648|bta:513129|SRC kinase signaling inhibitor 1 - - - - 14349 1380 3 3.56 0.24691474 Up 0.294031366 Fv1 Friend virus susceptibility 1 - - - GO:0051707//response to other organism gi|110665705|ref|NP_034374.2|/0/Friend virus susceptibility protein 1 [Mus musculus] 67841 2013 9.543333333 10.62666667 0.155123959 Up 0.293880928 Atg3 autophagy related 3 K08343|1|5e-172|607|mmu:67841|ubiquitin-like-conjugating enzyme ATG3 - - - - 68192 2609 7.75 8.696666667 0.166266228 Up 0.293833916 Leprotl1 leptin receptor overlapping transcript-like 1 - GO:0031224//intrinsic component of membrane - - gi|13386094|ref|NP_080885.1|/1.772e-69/leptin receptor overlapping transcript-like 1 [Mus musculus] 72344 5609 8.613333333 7.666666667 -0.167972209 Down 0.293833916 Usp36 ubiquitin specific peptidase 36 K11855|1|0.0|1919|mmu:72344|ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019941//modification-dependent protein catabolic process "gi|148702709|gb|EDL34656.1|/0/mCG13907, isoform CRA_c, partial [Mus musculus]" 338368 2745 0.413333333 0.18 -1.199308808 Down 0.293692881 Fam109b "family with sequence similarity 109, member B" - GO:0005768//endosome;GO:0030135//coated vesicle GO:0042802//identical protein binding;GO:0008289//lipid binding GO:0016192//vesicle-mediated transport;GO:0023051//regulation of signaling;GO:0006996//organelle organization gi|28893563|ref|NP_796365.1|/4.39194e-127/sesquipedalian-2 [Mus musculus] 71833 5765 12.22333333 10.99666667 -0.152571488 Down 0.293692881 Dcaf7 DDB1 and CUL4 associated factor 7 K11805|1|0.0|724|gja:107109125|WD repeat-containing protein 68 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031981//nuclear lumen GO:0005488//binding GO:0001501//skeletal system development;GO:0032446//protein modification by small protein conjugation "gi|440890867|gb|ELR44950.1|/0/DDB1- and CUL4-associated factor 7, partial [Bos mutus]" 107045 3845 12.11666667 10.89 -0.153988909 Down 0.293692881 Lars leucyl-tRNA synthetase K01869|1|0.0|2312|mmu:107045|leucyl-tRNA synthetase [EC:6.1.1.4] GO:0044444//cytoplasmic part GO:0032550;GO:0052689//carboxylic ester hydrolase activity;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation gi|37360338|dbj|BAC98147.1|/0/mKIAA1352 protein [Mus musculus] 246735 711 1.813333333 2.263333333 0.319804923 Up 0.293664673 AY074887 cDNA sequence AY074887 "K03847|1|1e-06|42.0|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" GO:0044421;GO:0044424 - GO:0008283//cell proliferation;GO:0007165//signal transduction;GO:0022402//cell cycle process gi|21644595|ref|NP_660264.1|/1.65608e-45/cleft palate-related protein 1 [Mus musculus] 19229 3916.69 2.713333333 3.24 0.255927519 Up 0.293627064 Ptk2b PTK2 protein tyrosine kinase 2 beta K05871|1|0.0|1926|mmu:19229|focal adhesion kinase 2 [EC:2.7.10.2] GO:0031981//nuclear lumen;GO:0044425;GO:0044327//dendritic spine head;GO:0031252//cell leading edge;GO:0043232;GO:0044444//cytoplasmic part;GO:0005924//cell-substrate adherens junction;GO:0031981//nuclear lumen;GO:0044425;GO:0044327//dendritic spine head;GO:0031252//cell leading edge;GO:0043232;GO:0044444//cytoplasmic part;GO:0005924//cell-substrate adherens junction GO:0019901//protein kinase binding;GO:0004713//protein tyrosine kinase activity;GO:0060089;GO:0032550;GO:0019901//protein kinase binding;GO:0004713//protein tyrosine kinase activity;GO:0060089;GO:0032550 GO:0014070//response to organic cyclic compound;GO:0019221//cytokine-mediated signaling pathway;GO:0001894//tissue homeostasis;GO:0046683//response to organophosphorus;GO:0006182//cGMP biosynthetic process;GO:0006809//nitric oxide biosynthetic process;GO:0007254//JNK cascade;GO:0043406//positive regulation of MAP kinase activity;GO:0008283//cell proliferation;GO:0038127//ERBB signaling pathway;GO:0010919//regulation of inositol phosphate biosynthetic process;GO:0001525//angiogenesis;GO:0097305//response to alcohol;GO:0043066//negative regulation of apoptotic process;GO:0010594//regulation of endothelial cell migration;GO:0019722//calcium-mediated signaling;GO:0001952//regulation of cell-matrix adhesion;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0031398//positive regulation of protein ubiquitination;GO:0030041//actin filament polymerization;GO:0007044//cell-substrate junction assembly;GO:0003006//developmental process involved in reproduction;GO:0032526//response to retinoic acid;GO:0002313//mature B cell differentiation involved in immune response;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0030099//myeloid cell differentiation;GO:0030162//regulation of proteolysis;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0032770//positive regulation of monooxygenase activity;GO:0072593//reactive oxygen species metabolic process;GO:0009746;GO:0006412//translation;GO:0006813//potassium ion transport;GO:0016049//cell growth;GO:0030279//negative regulation of ossification;GO:0051017//actin filament bundle assembly;GO:0010975//regulation of neuron projection development;GO:0010038//response to metal ion;GO:0009719;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0000302//response to reactive oxygen species;GO:0031532//actin cytoskeleton reorganization;GO:0010522//regulation of calcium ion transport into cytosol;GO:0022604//regulation of cell morphogenesis;GO:0014070//response to organic cyclic compound;GO:0019221//cytokine-mediated signaling pathway;GO:0001894//tissue homeostasis;GO:0046683//response to organophosphorus;GO:0006182//cGMP biosynthetic process;GO:0006809//nitric oxide biosynthetic process;GO:0007254//JNK cascade;GO:0043406//positive regulation of MAP kinase activity;GO:0008283//cell proliferation;GO:0038127//ERBB signaling pathway;GO:0010919//regulation of inositol phosphate biosynthetic process;GO:0001525//angiogenesis;GO:0097305//response to alcohol;GO:0043066//negative regulation of apoptotic process;GO:0010594//regulation of endothelial cell migration;GO:0019722//calcium-mediated signaling;GO:0001952//regulation of cell-matrix adhesion;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0031398//positive regulation of protein ubiquitination;GO:0030041//actin filament polymerization;GO:0007044//cell-substrate junction assembly;GO:0003006//developmental process involved in reproduction;GO:0032526//response to retinoic acid;GO:0002313//mature B cell differentiation involved in immune response;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0030099//myeloid cell differentiation;GO:0030162//regulation of proteolysis;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0032770//positive regulation of monooxygenase activity;GO:0072593//reactive oxygen species metabolic process;GO:0009746;GO:0006412//translation;GO:0006813//potassium ion transport;GO:0016049//cell growth;GO:0030279//negative regulation of ossification;GO:0051017//actin filament bundle assembly;GO:0010975//regulation of neuron projection development;GO:0010038//response to metal ion;GO:0009719;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0000302//response to reactive oxygen species;GO:0031532//actin cytoskeleton reorganization;GO:0010522//regulation of calcium ion transport into cytosol;GO:0022604//regulation of cell morphogenesis "gi|148704055|gb|EDL36002.1|/0/PTK2 protein tyrosine kinase 2 beta, isoform CRA_b, partial [Mus musculus]" 77929 5195 2.643333333 3.173333333 0.263640708 Up 0.293627064 Yipf6 "Yip1 domain family, member 6" K20363|1|5e-07|60.5|bmy:Bm1_34720|protein transport protein YIP1 GO:0031224//intrinsic component of membrane;GO:0030133//transport vesicle GO:0005515//protein binding GO:0002066//columnar/cuboidal epithelial cell development "gi|148682253|gb|EDL14200.1|/7.48687e-166/Yip1 domain family, member 6, isoform CRA_b, partial [Mus musculus]" 67463 3033 3.193333333 2.66 -0.26363691 Down 0.293627064 Poc5 POC5 centriolar protein K16483|1|0.0|963|mmu:67463|centrosomal protein POC5 - - - - 54138 2425 38.92666667 42.25333333 0.118306349 Up 0.293598857 Atxn10 ataxin 10 K19323|1|0.0|937|mmu:54138|ataxin-10 GO:0043005//neuron projection;GO:0044444//cytoplasmic part;GO:0044297//cell body GO:0005515//protein binding GO:0048731//system development;GO:0030030//cell projection organization gi|83649709|ref|NP_058539.2|/0/ataxin-10 [Mus musculus] 29863 4127 3.876666667 4.52 0.221506082 Up 0.293580052 Pde7b phosphodiesterase 7B "K18436|1|0.0|921|mmu:29863|high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]" - "GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0043169//cation binding" GO:0019935//cyclic-nucleotide-mediated signaling "gi|148539997|ref|NP_038903.3|/0/cAMP-specific 3',5'-cyclic phosphodiesterase 7B [Mus musculus]" 21787 1947.38 36.97666667 40.27666667 0.123329113 Up 0.293476626 Tfg Trk-fused gene K09292|1|6e-110|400|mmu:21787|protein TFG - GO:0060089;GO:0005515//protein binding;GO:0005515//protein binding GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007165//signal transduction gi|356995942|ref|NP_001239372.1|/5.51755e-109/protein TFG isoform 2 [Mus musculus] 26941 1922 4.88 5.613333333 0.201976585 Up 0.293467223 Slc9a3r1 "solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1" K13365|1|4e-176|620|mmu:26941|Na(+)/H(+) exchange regulatory cofactor NHE-RF1 GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005902//microvillus;GO:0031252//cell leading edge;GO:0005903//brush border;GO:0044459 GO:0031690//adrenergic receptor binding;GO:0019904//protein domain specific binding;GO:0016247//channel regulator activity;GO:0019899//enzyme binding GO:0007010//cytoskeleton organization;GO:0042939//tripeptide transport;GO:0007588//excretion;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0012501//programmed cell death;GO:0006869//lipid transport;GO:0008283//cell proliferation;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:0008104//protein localization;GO:0043409//negative regulation of MAPK cascade;GO:0065003;GO:0030031//cell projection assembly;GO:0072502;GO:0070293//renal absorption;GO:0040013//negative regulation of locomotion;GO:0032415//regulation of sodium:proton antiporter activity;GO:0016477//cell migration gi|6755566|ref|NP_036160.1|/3.67511e-175/Na(+)/H(+) exchange regulatory cofactor NHE-RF1 [Mus musculus] 54632 3420.81 4.846666667 5.576666667 0.202410176 Up 0.293467223 Ftsj1 FtsJ RNA methyltransferase homolog 1 (E. coli) K14864|1|9e-157|557|mmu:54632|tRNA (cytidine32/guanosine34-2'-O)-methyltransferase [EC:2.1.1.205] - - - - 18673 1815 194.4333333 210.0333333 0.111342736 Up 0.293326188 Phb prohibitin K17080|1|1e-134|483|pale:102882690|prohibitin 1 GO:0031981//nuclear lumen;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane "GO:0000975//regulatory region DNA binding;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0019899//enzyme binding" "GO:0006476//protein deacetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0008585//female gonad development;GO:0030521//androgen receptor signaling pathway;GO:0006915//apoptotic process;GO:0006259//DNA metabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0033144//negative regulation of intracellular steroid hormone receptor signaling pathway;GO:0009887//organ morphogenesis;GO:0097305//response to alcohol;GO:0070741//response to interleukin-6;GO:0016049//cell growth;GO:0009725//response to hormone" gi|488527295|ref|XP_004455467.1|/1.09638e-138/PREDICTED: prohibitin isoform X1 [Dasypus novemcinctus] 16511 4089.17 37.04666667 40.33 0.122509666 Up 0.293316785 Kcnh2 "potassium voltage-gated channel, subfamily H (eag-related), member 2" K04905|1|0.0|2021|rno:117018|potassium voltage-gated channel Eag-related subfamily H member 2 GO:0016021//integral component of membrane;GO:0044424;GO:0012505//endomembrane system;GO:0044424;GO:0012505//endomembrane system;GO:0005887//integral component of plasma membrane GO:0004673//protein histidine kinase activity;GO:0060089;GO:0005249//voltage-gated potassium channel activity;GO:0004673//protein histidine kinase activity;GO:0060089;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity "GO:0006351//transcription, DNA-templated;GO:0002027//regulation of heart rate;GO:0030001//metal ion transport;GO:0060306//regulation of membrane repolarization;GO:0051259//protein oligomerization;GO:0007165//signal transduction;GO:0006351//transcription, DNA-templated;GO:0002027//regulation of heart rate;GO:0003012//muscle system process;GO:0007267//cell-cell signaling;GO:0030001//metal ion transport;GO:0060306//regulation of membrane repolarization;GO:0051259//protein oligomerization;GO:0007165//signal transduction" gi|157042785|ref|NP_038597.2|/0/potassium voltage-gated channel subfamily H member 2 isoform 1 [Mus musculus] 72609 1746 1.023333333 1.39 0.441808728 Up 0.293269773 2700070H01Rik RIKEN cDNA 2700070H01 gene - - - - - 194126 2812 1.673333333 2.11 0.334518135 Up 0.293250968 Mtmr11 myotubularin related protein 11 K18085|1|0.0|1326|mmu:194126|myotubularin-related protein 10/11/12 - GO:0042578//phosphoric ester hydrolase activity GO:0006796//phosphate-containing compound metabolic process gi|224994246|ref|NP_852074.2|/0/myotubularin-related protein 11 [Mus musculus] 52708 2723.41 10.28333333 9.216666667 -0.157991009 Down 0.293222761 Zfp410 zinc finger protein 410 K09228|1|1e-33|148|bfo:BRAFLDRAFT_83455|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|357588468|ref|NP_001239511.1|/0/zinc finger protein 410 isoform 2 [Mus musculus] 68420 3316 23.32333333 21.34 -0.128213815 Down 0.293175749 Ankrd13a ankyrin repeat domain 13a K05766|1|6e-157|557|ssc:100515297|protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48];K16943|2|7e-143|511|tca:655956|septin 4;K00910|3|8e-38|162|apla:101801089|beta-adrenergic-receptor kinase [EC:2.7.11.15] - - - - 100038847 1955 0.663333333 0.383333333 -0.79113457 Down 0.29313814 Gm10406 predicted gene 10406 "K03844|1|2e-16|90.5|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - gi|755546841|ref|XP_011243026.1|/1.83585e-122/PREDICTED: predicted gene 3264 isoform X1 [Mus musculus] 73677 1693 0.416666667 0.183333333 -1.184424571 Down 0.293091128 Psma8 "proteasome (prosome, macropain) subunit, alpha type, 8" K02731|1|1e-123|446|mmu:73677|20S proteasome subunit alpha 4 [EC:3.4.25.1] GO:0005839//proteasome core complex;GO:0043231//intracellular membrane-bounded organelle GO:0004175//endopeptidase activity GO:0019941//modification-dependent protein catabolic process "gi|148669642|gb|EDL01589.1|/9.23674e-127/mCG144520, partial [Mus musculus]" 69104 2647.82 37.38333333 40.62 0.119795025 Up 0.293072323 5-Mar membrane-associated ring finger (C3HC4) 5 K10660|1|4e-161|572|mdo:100024142|E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27] - - - - 22666 3602 5.066666667 4.383333333 -0.209008524 Down 0.293062921 Zbtb14 zinc finger and BTB domain containing 14 K10500|1|7e-45|185|bacu:103010937|zinc finger and BTB domain-containing protein 17 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0006366//transcription from RNA polymerase II promoter gi|6678637|ref|NP_033573.1|/0/zinc finger and BTB domain-containing protein 14 [Mus musculus] 77254 1135.75 36.40333333 39.63 0.122522408 Up 0.293034714 Yif1b Yip1 interacting factor homolog B (S. cerevisiae) K20362|1|6e-161|569|mmu:77254|protein transport protein YIF1 - - - - 11840 1802.4 181.4966667 196.1666667 0.112136862 Up 0.292987702 Arf1 ADP-ribosylation factor 1 K07937|1|4e-100|368|lve:103088013|ADP-ribosylation factor 1 GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0012505//endomembrane system GO:0004871//signal transducer activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0004871//signal transducer activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0030003//cellular cation homeostasis;GO:0046474//glycerophospholipid biosynthetic process;GO:0044764;GO:0035964//COPI-coated vesicle budding;GO:0050688//regulation of defense response to virus;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0002478;GO:0035556//intracellular signal transduction;GO:0030003//cellular cation homeostasis;GO:0046474//glycerophospholipid biosynthetic process;GO:0044764;GO:0035964//COPI-coated vesicle budding;GO:0050688//regulation of defense response to virus;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0002478;GO:0035556//intracellular signal transduction gi|672068062|ref|XP_008766092.1|/7.44069e-106/PREDICTED: ADP-ribosylation factor 1 isoform X2 [Rattus norvegicus] 360213 2731 0.413333333 0.183333333 -1.172836597 Down 0.292959495 Trim46 tripartite motif-containing 46 K12022|1|0.0|790|ngi:103750975|tripartite motif-containing protein 46 GO:0044464 GO:0046914//transition metal ion binding - gi|87080829|ref|NP_001034555.1|/0/tripartite motif-containing protein 46 isoform 3 [Mus musculus] 14714 580 0.796666667 0.5 -0.672048117 Down 0.292762044 Gnrh1 gonadotropin releasing hormone 1 K05252|1|5e-20|98.2|mmu:14714|gonadotropin-releasing hormone - - - - 229003 10124 6.416666667 5.633333333 -0.187835199 Down 0.29274324 Helz2 "helicase with zinc finger 2, transcriptional coactivator" K14326|1|9e-49|200|cbr:CBG08494|regulator of nonsense transcripts 1 [EC:3.6.4.-] - - - gi|125347767|ref|NP_898985.2|/0/helicase with zinc finger domain 2 [Mus musculus] 73338 3689 6.243333333 5.463333333 -0.192535045 Down 0.29274324 Itpripl1 "inositol 1,4,5-triphosphate receptor interacting protein-like 1" - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|148696226|gb|EDL28173.1|/0/mCG51762 [Mus musculus] 14789 2779 5.52 6.296666667 0.189920029 Up 0.29274324 P3h3 prolyl 3-hydroxylase 3 K08134|1|2e-126|456|tup:102468745|leucine proline-enriched proteoglycan (leprecan) GO:0044432 "GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798//procollagen-proline dioxygenase activity;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0043062//extracellular structure organization;GO:0008283//cell proliferation;GO:0044710 gi|47523368|ref|NP_038562.2|/0/prolyl 3-hydroxylase 3 precursor [Mus musculus] 76508 1840 10.86 12.06666667 0.152003093 Up 0.292724435 Ube2d-ps "ubiquitin-conjugating enzyme E2D, pseudogene" K06689|1|5e-42|175|cge:100768634|ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23] - - - "gi|148708602|gb|EDL40549.1|/1.23909e-63/mCG14703, isoform CRA_a, partial [Mus musculus]" 29877 5868 2.046666667 2.513333333 0.296325868 Up 0.292715033 Hdgfrp3 "hepatoma-derived growth factor, related protein 3" K16641|1|1e-45|189|lcm:102349153|hepatoma-derived growth factor GO:0031981//nuclear lumen - GO:0044699 gi|26337455|dbj|BAC32413.1|/9.17717e-83/unnamed protein product [Mus musculus] 73389 2942.22 35.21666667 38.4 0.12484795 Up 0.292621009 Hbp1 high mobility group box transcription factor 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006813//potassium ion transport;GO:0007166//cell surface receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006813//potassium ion transport;GO:0007166//cell surface receptor signaling pathway;GO:0006351//transcription, DNA-templated" "gi|148704955|gb|EDL36902.1|/0/high mobility group box transcription factor 1, isoform CRA_b, partial [Mus musculus]" 16493 3032 21.37666667 23.32333333 0.125737084 Up 0.292611606 Kcna5 "potassium voltage-gated channel, shaker-related subfamily, member 5" K04878|1|0.0|981|mmu:16493|potassium voltage-gated channel Shaker-related subfamily A member 5 - - - - 80292 4162.78 7.333333333 6.483333333 -0.177733369 Down 0.29250818 Zxdc ZXD family zinc finger C K10485|1|2e-72|277|myd:102773583|BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1);K09228|5|6e-43|179|obi:106879898|KRAB domain-containing zinc finger protein - - - - 27981 1415 37.09666667 40.26 0.118057613 Up 0.292470571 Rsrp1 arginine/serine rich protein 1 - - - - gi|148539955|ref|NP_076154.3|/9.32474e-58/arginine/serine-rich protein 1 [Mus musculus] 12766 1609 0.036666667 0.216666667 2.562936194 Up 0.292470571 Cxcr3 chemokine (C-X-C motif) receptor 3 K04188|1|6e-154|546|mmu:12766|C-X-C chemokine receptor type 3 GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0044424 GO:0004950//chemokine receptor activity;GO:0019955//cytokine binding GO:0022610;GO:0007600//sensory perception;GO:0019932//second-messenger-mediated signaling;GO:0019221//cytokine-mediated signaling pathway;GO:0048247//lymphocyte chemotaxis;GO:0051480//regulation of cytosolic calcium ion concentration gi|6753458|ref|NP_034040.1|/5.3587e-153/C-X-C chemokine receptor type 3 [Mus musculus] 14705 1730.23 13.91 15.37333333 0.144307592 Up 0.292442363 Bscl2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) K19365|1|0.0|707|cge:100755147|seipin - - - - 100034361 1887 16.16666667 14.70666667 -0.136551956 Down 0.292442363 Mfap1b microfibrillar-associated protein 1B K13110|1|1e-142|509|mmu:100034361|microfibrillar-associated protein 1 GO:0043205//fibril - - gi|26328395|dbj|BAC27936.1|/9.18044e-179/unnamed protein product [Mus musculus] 66578 1300 1.91 2.373333333 0.313342102 Up 0.292423559 Mis18a MIS18 kinetochore protein A K11564|1|3e-102|374|mmu:66578|kinetochore protein Mis18 GO:0043231//intracellular membrane-bounded organelle;GO:0043232 - GO:0000087//mitotic M phase gi|12851734|dbj|BAB29147.1|/1.35182e-105/unnamed protein product [Mus musculus] 59093 2175 1.946666667 2.41 0.308027278 Up 0.292423559 Pcbp3 poly(rC) binding protein 3 K13162|1|0.0|712|mmu:59093|poly(rC)-binding protein 2/3/4 GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding - gi|171906586|ref|NP_067543.2|/0/poly(rC)-binding protein 3 [Mus musculus] 22770 5105 2.976666667 2.47 -0.269186633 Down 0.292301328 Zhx1 zinc fingers and homeoboxes 1 - GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity GO:0048869//cellular developmental process;GO:0006366//transcription from RNA polymerase II promoter gi|60360160|dbj|BAD90299.1|/0/mKIAA4149 protein [Mus musculus] 21969 3859 8.16 7.23 -0.174573505 Down 0.292282523 Top1 topoisomerase (DNA) I K03163|1|0.0|1130|mmu:21969|DNA topoisomerase I [EC:5.99.1.2] - - - gi|112734855|ref|NP_033434.2|/0/DNA topoisomerase 1 [Mus musculus] 14455 2554 3.736666667 4.366666667 0.224780534 Up 0.292282523 Gas5 growth arrest specific 5 - - - - gi|344235252|gb|EGV91355.1|/1.21705e-06/hypothetical protein I79_025987 [Cricetulus griseus] 99382 4595 8.52 7.586666667 -0.167387279 Down 0.292282523 Abtb2 ankyrin repeat and BTB (POZ) domain containing 2 K10521|1|0.0|1861|mmu:99382|ankyrin repeat and BTB/POZ domain-containing protein 2 - GO:0046983//protein dimerization activity - "gi|148695752|gb|EDL27699.1|/0/ankyrin repeat and BTB (POZ) domain containing 2, isoform CRA_b, partial [Mus musculus]" 71146 2830 0.243333333 0.053333333 -2.189824559 Down 0.29227312 Golga7b "golgi autoantigen, golgin subfamily a, 7B" "K11728|1|8e-23|112|smm:Smp_129330|nucleosome-remodeling factor subunit BPTF;K05546|2|2e-22|110|tsp:Tsp_01492|alpha 1,3-glucosidase [EC:3.2.1.84];K17584|3|4e-06|56.6|acs:100554132|phosphorylated CTD-interacting factor 1" GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle - - gi|74228183|dbj|BAE23972.1|/6.85438e-115/unnamed protein product [Mus musculus] 73674 2612 5.643333333 4.926666667 -0.195935704 Down 0.29227312 Wdr75 WD repeat domain 75 K14552|1|0.0|1623|mmu:73674|NET1-associated nuclear protein 1 (U3 small nucleolar RNA-associated protein 17) - - - gi|83523742|ref|NP_082875.1|/0/WD repeat-containing protein 75 [Mus musculus] 27407 2572.83 36.59333333 39.71333333 0.11804262 Up 0.292235511 Abcf2 "ATP-binding cassette, sub-family F (GCN20), member 2" "K06185|1|0.0|1115|mmu:27407|ATP-binding cassette, subfamily F, member 2" GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 - gi|299473734|ref|NP_001177372.1|/0/ATP-binding cassette sub-family F member 2 isoform 2 [Mus musculus] 67101 801 13.77666667 15.22666667 0.144373287 Up 0.292169694 2310039H08Rik RIKEN cDNA 2310039H08 gene - - - - gi|13385462|ref|NP_080242.1|/1.1542e-59/uncharacterized protein C6orf226 homolog [Mus musculus] 216825 4442 10.16 9.106666667 -0.157905419 Down 0.292132085 Usp22 ubiquitin specific peptidase 22 K11366|1|0.0|1113|mmu:216825|ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12] GO:0070461//SAGA-type complex GO:0046914//transition metal ion binding;GO:0004402//histone acetyltransferase activity;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0003713//transcription coactivator activity "GO:0000278//mitotic cell cycle;GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0016567//protein ubiquitination;GO:0019941//modification-dependent protein catabolic process;GO:0070646//protein modification by small protein removal;GO:0016573//histone acetylation" gi|60360058|dbj|BAD90248.1|/0/mKIAA1063 protein [Mus musculus] 56703 3883.65 9.866666667 8.813333333 -0.162874999 Down 0.292132085 Pigo "phosphatidylinositol glycan anchor biosynthesis, class O" "K05288|1|0.0|1724|mmu:56703|phosphatidylinositol glycan, class O" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005488//binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005488//binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005488//binding" GO:0006497//protein lipidation;GO:0006497//protein lipidation;GO:0006497//protein lipidation gi|239937480|ref|NP_064419.2|/0/GPI ethanolamine phosphate transferase 3 isoform 1 [Mus musculus] 26409 5740.41 8.88 9.933333333 0.161718248 Up 0.292132085 Map3k7 mitogen-activated protein kinase kinase kinase 7 K04427|1|0.0|1021|mmu:26409|mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25] GO:0031090//organelle membrane;GO:0000123//histone acetyltransferase complex;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane;GO:0000123//histone acetyltransferase complex;GO:0044444//cytoplasmic part GO:0046872//metal ion binding;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0032550;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0046872//metal ion binding;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0032550;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006915//apoptotic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0002369//T cell cytokine production;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0050851//antigen receptor-mediated signaling pathway;GO:0032147//activation of protein kinase activity;GO:0043069//negative regulation of programmed cell death;GO:0043406//positive regulation of MAP kinase activity;GO:0072593//reactive oxygen species metabolic process;GO:0007254//JNK cascade;GO:0001819//positive regulation of cytokine production;GO:0001838//embryonic epithelial tube formation;GO:0016573//histone acetylation;GO:0002753;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0042110//T cell activation;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006915//apoptotic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0002369//T cell cytokine production;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0050851//antigen receptor-mediated signaling pathway;GO:0032147//activation of protein kinase activity;GO:0043069//negative regulation of programmed cell death;GO:0043406//positive regulation of MAP kinase activity;GO:0072593//reactive oxygen species metabolic process;GO:0007254//JNK cascade;GO:0001819//positive regulation of cytokine production;GO:0001838//embryonic epithelial tube formation;GO:0016573//histone acetylation;GO:0002753;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0042110//T cell activation gi|27881429|ref|NP_766276.1|/0/mitogen-activated protein kinase kinase kinase 7 isoform A [Mus musculus] 104080 1675 0.513333333 0.81 0.658025963 Up 0.292122682 Nxph4 neurexophilin 4 K00600|1|4e-74|281|aam:106482143|glycine hydroxymethyltransferase [EC:2.1.2.1];K04550|2|9e-74|280|asn:102370838|low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor);K16657|3|4e-70|268|lcm:102355521|neurexophilin-2 - - GO:0007186//G-protein coupled receptor signaling pathway gi|117676393|ref|NP_899120.2|/1.22767e-139/neurexophilin-4 precursor [Mus musculus] 71607 1434 0.593333333 0.903333333 0.60641561 Up 0.292047463 Snx20 sorting nexin 20 K17931|1|1e-142|508|mmu:71607|sorting nexin-20 - - - - 233189 2476 1.523333333 1.946666667 0.353774204 Up 0.291962842 Ctu1 cytosolic thiouridylase subunit 1 K14168|1|0.0|719|mmu:233189|cytoplasmic tRNA 2-thiolation protein 1 [EC:2.7.7.-] - - - - 52915 4008.65 34.39666667 37.47333333 0.123595552 Up 0.291944037 Zmiz2 "zinc finger, MIZ-type containing 2" K06794|1|8e-37|159|ocu:100359021|neurocan core protein;K16063|2|1e-18|99.0|mdo:100018269|E3 SUMO-protein ligase PIAS2 GO:0031981//nuclear lumen;GO:0005657//replication fork;GO:0031981//nuclear lumen;GO:0005657//replication fork GO:0046914//transition metal ion binding;GO:0003713//transcription coactivator activity;GO:0046914//transition metal ion binding;GO:0003713//transcription coactivator activity GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter gi|54607102|ref|NP_001005867.1|/0/zinc finger MIZ domain-containing protein 2 isoform 2 [Mus musculus] 319711 832 0.246666667 0.056666667 -2.121990524 Down 0.291897025 E230029C05Rik RIKEN cDNA E230029C05 gene - - - - "gi|149069011|gb|EDM18563.1|/2.88636e-28/rCG39989, isoform CRA_b [Rattus norvegicus]" 73182 4416.75 12.34 11.15 -0.146298684 Down 0.291850013 Pear1 platelet endothelial aggregation receptor 1 K02258|1|1e-132|477|hmg:100209451|cytochrome c oxidase assembly protein subunit 11;K06709|4|8e-113|411|crg:105346814|jumonji domain-containing protein 2 [EC:1.14.11.-] GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane - "GO:0006910//phagocytosis, recognition;GO:0006910//phagocytosis, recognition;GO:0006910//phagocytosis, recognition;GO:0006910//phagocytosis, recognition;GO:0006910//phagocytosis, recognition;GO:0006910//phagocytosis, recognition" "gi|148683402|gb|EDL15349.1|/0/RIKEN cDNA 3110045G13, isoform CRA_b, partial [Mus musculus]" 234854 1661 10.67 11.85666667 0.152138298 Up 0.291850013 Cdk10 cyclin-dependent kinase 10 K02449|1|0.0|646|mmu:234854|cyclin-dependent kinase 10 [EC:2.7.11.22] - - - - 72045 2285 0.073333333 0.273333333 1.898120386 Up 0.291831208 Mfsd4b2 major facilitator superfamily domain containing 4B2 "K08175|1|0.0|692|rno:499462|MFS transporter, FHS family, Na+ dependent glucose transporter 1" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0030001//metal ion transport;GO:0044763 gi|149032986|gb|EDL87827.1|/0/rCG19957 [Rattus norvegicus] 67418 2910 4.353333333 5.026666667 0.207481532 Up 0.291821806 Ppil4 peptidylprolyl isomerase (cyclophilin)-like 4 K12735|1|0.0|778|mmu:67418|peptidyl-prolyl cis-trans isomerase-like 4 [EC:5.2.1.8] GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0016859//cis-trans isomerase activity GO:0044267//cellular protein metabolic process "gi|148671591|gb|EDL03538.1|/0/peptidylprolyl isomerase (cyclophilin)-like 4, isoform CRA_a, partial [Mus musculus]" 22057 2288 39.22 36.16 -0.117194858 Down 0.291774794 Tob1 transducer of ErbB-2.1 K14443|1|4e-148|528|mmu:22057|protein Tob/BTG GO:0044424 GO:0005515//protein binding GO:0001649//osteoblast differentiation;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006606//protein import into nucleus;GO:0030509//BMP signaling pathway gi|61676219|ref|NP_033453.2|/3.08562e-147/protein Tob1 [Mus musculus] 16973 5172 39.87666667 36.81666667 -0.115185805 Down 0.291774794 Lrp5 low density lipoprotein receptor-related protein 5 K03068|1|0.0|3224|mmu:16973|low density lipoprotein receptor-related protein 5/6 - - - gi|60360254|dbj|BAD90371.1|/0/mKIAA4142 protein [Mus musculus] 78755 3545.77 1.066666667 1.44 0.432959407 Up 0.291774794 Fam122b "family with sequence similarity 122, member B" - - - - "gi|42542783|gb|AAH66167.1|/5.84705e-116/Family with sequence similarity 122, member B [Mus musculus]" 270802 3134 0.876666667 1.226666667 0.484642967 Up 0.29168077 BC048403 cDNA sequence BC048403 - - - - gi|755534598|ref|XP_011241760.1|/0/PREDICTED: UPF0536 protein C12orf66 homolog isoform X2 [Mus musculus] 192212 4224 0.06 0.253333333 2.078002512 Up 0.291614954 Prom2 prominin 2 K15602|1|0.0|1414|mmu:192212|prominin 2 GO:0012505//endomembrane system;GO:0044459;GO:0005902//microvillus;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0031224//intrinsic component of membrane;GO:0012505//endomembrane system;GO:0044459;GO:0005902//microvillus;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0031224//intrinsic component of membrane GO:0005102//receptor binding;GO:0005102//receptor binding - gi|20086520|gb|AAM10543.1|AF269062_1/0/prominin-2 [Mus musculus] 207965 1027 3.146666667 2.623333333 -0.262423224 Down 0.291614954 Vcpkmt valosin containing protein lysine (K) methyltransferase K02357|1|2e-13|79.3|pale:102895576|elongation factor Ts - GO:0008276//protein methyltransferase activity GO:0018022//peptidyl-lysine methylation gi|755542397|ref|XP_011242354.1|/4.34954e-130/PREDICTED: protein-lysine methyltransferase METTL21D isoform X1 [Mus musculus] 234797 5535 3.773333333 3.2 -0.237767647 Down 0.291605551 6430548M08Rik RIKEN cDNA 6430548M08 gene K10898|1|7e-19|100|cmk:103188076|fanconi anemia-associated protein - - - gi|28972255|dbj|BAC65581.1|/0/mKIAA0513 protein [Mus musculus] 665270 1522.06 0.736666667 0.45 -0.711086962 Down 0.291586746 Plb1 phospholipase B1 "K14621|1|9e-105|381|mmu:665270|phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]" GO:0044459;GO:0005903//brush border;GO:0031224//intrinsic component of membrane;GO:0005903//brush border;GO:0005886//plasma membrane;GO:0031224//intrinsic component of membrane;GO:0005903//brush border;GO:0031224//intrinsic component of membrane GO:0004620//phospholipase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0004620//phospholipase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0004620//phospholipase activity;GO:0052689//carboxylic ester hydrolase activity GO:0006796//phosphate-containing compound metabolic process;GO:0001523//retinoid metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0001523//retinoid metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0001523//retinoid metabolic process "gi|124487227|ref|NP_001074876.1|/0/phospholipase B1, membrane-associated isoform 1 precursor [Mus musculus]" 52882 5828 0.463333333 0.756666667 0.707607415 Up 0.291586746 Rgs7bp regulator of G-protein signalling 7 binding protein K15708|1|5e-97|359|mgp:100539017|E3 ubiquitin-protein ligase RNF180 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane - GO:0007166//cell surface receptor signaling pathway gi|119360350|ref|NP_084155.2|/1.19179e-135/regulator of G-protein signaling 7-binding protein [Mus musculus] 14159 2780 10.06666667 9.03 -0.156788156 Down 0.291577344 Fes feline sarcoma oncogene K07527|1|0.0|1576|mmu:14159|tyrosine-protein kinase Fes/Fps [EC:2.7.10.2] GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0005924//cell-substrate adherens junction;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part;GO:0009898//cytoplasmic side of plasma membrane GO:0005102//receptor binding;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0005543//phospholipid binding GO:0022604//regulation of cell morphogenesis;GO:0007155//cell adhesion;GO:0008283//cell proliferation;GO:0002886;GO:0010975//regulation of neuron projection development;GO:0016192//vesicle-mediated transport;GO:0031112;GO:0006468//protein phosphorylation;GO:0030099//myeloid cell differentiation;GO:0006935//chemotaxis;GO:0031532//actin cytoskeleton reorganization;GO:0040012//regulation of locomotion gi|111185914|ref|NP_034324.2|/0/tyrosine-protein kinase Fes/Fps [Mus musculus] 246154 3189 6.163333333 7.003333333 0.184330937 Up 0.291567942 Vasn vasorin K16351|1|1e-18|98.2|sko:100378039|netrin-G2 ligand;K13023|2|7e-15|85.9|bfo:BRAFLDRAFT_89744|carboxypeptidase N regulatory subunit;K06838|3|9e-15|85.5|umr:103658831|slit 1 GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane - GO:0051775//response to redox state;GO:0001666//response to hypoxia gi|31981693|ref|NP_647468.2|/0/vasorin precursor [Mus musculus] 21873 4632.7 8.333333333 7.41 -0.169420147 Down 0.291549137 Tjp2 tight junction protein 2 K06098|1|0.0|2050|mmu:21873|tight junction protein 2 GO:0016020//membrane;GO:0043296//apical junction complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043296//apical junction complex;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0005515//protein binding GO:0042221//response to chemical;GO:0042221//response to chemical gi|312222765|ref|NP_001185914.1|/0/tight junction protein ZO-2 isoform 1 [Mus musculus] 100502829 4823 7.17 8.086666667 0.173572026 Up 0.291549137 Gm9899 predicted gene 9899 K04914|1|2e-26|124|ngi:103735664|potassium channel subfamily K member 3 GO:0031224//intrinsic component of membrane GO:0005249//voltage-gated potassium channel activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity GO:0001666//response to hypoxia;GO:0007417//central nervous system development;GO:0044767//single-organism developmental process;GO:0010043//response to zinc ion;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0051480//regulation of cytosolic calcium ion concentration gi|26331072|dbj|BAC29266.1|/6.18918e-91/unnamed protein product [Mus musculus] 12501 1436 0.076666667 0.276666667 1.851477475 Up 0.291492723 Cd3e "CD3 antigen, epsilon polypeptide" K06451|1|1e-97|359|mmu:12501|T-cell surface glycoprotein CD3 epsilon chain GO:0042101//T cell receptor complex;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0038023//signaling receptor activity;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding GO:0001934//positive regulation of protein phosphorylation;GO:0002666//positive regulation of T cell tolerance induction;GO:0050851//antigen receptor-mediated signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0001819//positive regulation of cytokine production;GO:0042094//interleukin-2 biosynthetic process;GO:0007224//smoothened signaling pathway;GO:0019722//calcium-mediated signaling;GO:0043383//negative T cell selection;GO:0031667//response to nutrient levels gi|6680886|ref|NP_031674.1|/1.04103e-96/T-cell surface glycoprotein CD3 epsilon chain precursor [Mus musculus] 20422 491 140.15 151.0433333 0.107990764 Up 0.29148332 Shfm1 split hand/foot malformation (ectrodactyly) type 1 K10881|1|1e-17|90.9|pale:102881642|26 proteasome complex subunit DSS1 "GO:0016591//DNA-directed RNA polymerase II, holoenzyme" GO:0005488//binding;GO:0016787//hydrolase activity GO:0019538//protein metabolic process;GO:0000725//recombinational repair gi|586557376|ref|XP_006911988.1|/7.16213e-17/PREDICTED: 26S proteasome complex subunit DSS1 [Pteropus alecto] 66085 1507 139.6633333 150.4466667 0.107298831 Up 0.291426906 Eif3f "eukaryotic translation initiation factor 3, subunit F" K03249|1|3e-149|530|mmu:66085|translation initiation factor 3 subunit F GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0008135//translation factor activity, RNA binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0006412//translation gi|74207432|dbj|BAE30896.1|/2.79162e-148/unnamed protein product [Mus musculus] 73112 826 10.53666667 11.71666667 0.153143654 Up 0.291351687 Abracl ABRA C-terminal like - - - - "gi|24980968|gb|AAH39801.1|/2.65262e-38/3110003A17Rik protein, partial [Mus musculus]" 384009 2019 1.766666667 2.206666667 0.320838857 Up 0.291304675 Glipr2 GLI pathogenesis-related 2 "K19867|1|2e-27|127|sko:100371303|LIM domain-binding protein 3;K19919|2|2e-12|76.6|shr:100924579|cysteine-rich secretory protein;K14388|3|3e-12|76.3|sko:102803350|solute carrier family 5 (sodium-coupled monocarboxylate transporter), member 8/12" GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle - - gi|744610930|ref|XP_010993879.1|/1.8026e-87/PREDICTED: golgi-associated plant pathogenesis-related protein 1 [Camelus dromedarius] 100038526 843 0.6 0.906666667 0.595609745 Up 0.291210651 Gm10560 predicted gene 10560 - - - - - 171167 3248.47 1.166666667 0.826666667 -0.497014801 Down 0.291173041 Fut10 fucosyltransferase 10 "K09669|1|0.0|839|mmu:171167|alpha-1,3-fucosyltransferase 10 [EC:2.4.1.-]" GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane GO:0008417//fucosyltransferase activity;GO:0008417//fucosyltransferase activity;GO:0008417//fucosyltransferase activity;GO:0008417//fucosyltransferase activity;GO:0008417//fucosyltransferase activity GO:0006464//cellular protein modification process;GO:0070085//glycosylation;GO:0006464//cellular protein modification process;GO:0070085//glycosylation;GO:0006464//cellular protein modification process;GO:0070085//glycosylation;GO:0006464//cellular protein modification process;GO:0070085//glycosylation;GO:0006464//cellular protein modification process;GO:0070085//glycosylation "gi|60302885|ref|NP_001012535.1|/0/alpha-(1,3)-fucosyltransferase 10 isoform a [Mus musculus]" 19220 4414 1.253333333 1.64 0.387925654 Up 0.291163639 Ptgfr prostaglandin F receptor K04262|1|0.0|686|mmu:19220|prostaglandin F receptor GO:0031224//intrinsic component of membrane;GO:0044424 GO:0004955//prostaglandin receptor activity GO:0002237//response to molecule of bacterial origin;GO:0007166//cell surface receptor signaling pathway;GO:0006915//apoptotic process gi|6679533|ref|NP_032992.1|/0/prostaglandin F2-alpha receptor [Mus musculus] 100038347 2678 125.3633333 135.7033333 0.114340713 Up 0.291135432 Fam174b "family with sequence similarity 174, member B" "K10364|1|3e-15|86.7|cmy:102944071|capping protein (actin filament) muscle Z-line, alpha" - - - gi|242117959|ref|NP_001156004.1|/1.27008e-46/membrane protein FAM174B precursor [Mus musculus] 20475 2853 4.83 5.54 0.197862787 Up 0.291079018 Six5 sine oculis-related homeobox 5 K19474|1|0.0|1017|mmu:20475|homeobox protein SIX5 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0007281//germ cell development;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation" gi|73532776|ref|NP_035513.1|/0/homeobox protein SIX5 [Mus musculus] 53601 5587 5.47 4.763333333 -0.199569322 Down 0.291079018 Pcdh12 protocadherin 12 K16499|1|0.0|2147|mmu:53601|protocadherin delta 2 GO:0030054//cell junction;GO:0016021//integral component of membrane GO:0046872//metal ion binding GO:0006073//cellular glucan metabolic process;GO:0016337//single organismal cell-cell adhesion;GO:0048232//male gamete generation;GO:0001892//embryonic placenta development gi|120444908|ref|NP_059074.2|/0/protocadherin-12 precursor [Mus musculus] 68277 2214 5.456666667 4.75 -0.200092403 Down 0.291079018 2310057M21Rik RIKEN cDNA 2310057M21 gene - - GO:0005515//protein binding - gi|21311825|ref|NP_080931.1|/0/uncharacterized protein C10orf88 homolog [Mus musculus] 15013 1100 0.613333333 0.346666667 -0.823122238 Down 0.290994396 H2-Q2 "histocompatibility 2, Q region locus 2" "K06751|1|0.0|671|mmu:15013|major histocompatibility complex, class I" GO:0031224//intrinsic component of membrane;GO:0042611;GO:0009986//cell surface GO:0005515//protein binding GO:0002484;GO:0002664//regulation of T cell tolerance induction;GO:0009581;GO:0001817//regulation of cytokine production "gi|148694675|gb|EDL26622.1|/0/mCG134629, isoform CRA_d [Mus musculus]" 100038566 1133 0.353333333 0.623333333 0.818974005 Up 0.290994396 Gm10658 predicted gene 10658 K18038|1|2e-14|82.8|ggo:101151279|tyrosine-protein phosphatase non-receptor type 9 [EC:3.1.3.48] - - - - 77318 2781 0.366666667 0.15 -1.289506617 Down 0.29089097 Ankrd55 ankyrin repeat domain 55 K19626|1|2e-41|173|crg:105319221|inversin - - - gi|270288790|ref|NP_001161876.1|/1.75122e-152/ankyrin repeat domain-containing protein 55 isoform 3 [Mus musculus] 52502 2849 14.33 15.74 0.135396931 Up 0.29089097 Carhsp1 calcium regulated heat stable protein 1 K15441|1|3e-28|130|tsp:Tsp_04322|tRNA-specific adenosine deaminase 2 [EC:3.5.4.-];K00503|2|7e-08|62.4|pxy:105395691|dopamine beta-monooxygenase [EC:1.14.17.1] GO:0000178//exosome (RNase complex);GO:0035770//ribonucleoprotein granule;GO:0044444//cytoplasmic part GO:0003729//mRNA binding "GO:0019932//second-messenger-mediated signaling;GO:0006351//transcription, DNA-templated;GO:0043487//regulation of RNA stability" gi|13385290|ref|NP_080097.1|/4.08064e-75/calcium-regulated heat stable protein 1 [Mus musculus] 72881 1363 15.03666667 13.62666667 -0.14205209 Down 0.29089097 Zdhhc4 "zinc finger, DHHC domain containing 4" K20003|1|2e-173|611|mmu:72881|palmitoyltransferase ZDHHC4 [EC:2.3.1.225] GO:0031224//intrinsic component of membrane GO:0016740//transferase activity;GO:0046914//transition metal ion binding - "gi|148687109|gb|EDL19056.1|/1.03268e-177/zinc finger, DHHC domain containing 4, isoform CRA_b [Mus musculus]" 239510 6670 3.87 4.493333333 0.215452524 Up 0.290872165 Phf20l1 PHD finger protein 20-like 1 K18402|1|0.0|1803|mmu:239510|PHD finger protein 20 - GO:0046914//transition metal ion binding - gi|124487195|ref|NP_001074878.1|/0/PHD finger protein 20-like protein 1 [Mus musculus] 14772 3229.53 7.473333333 8.386666667 0.166345644 Up 0.29085336 Grk4 G protein-coupled receptor kinase 4 K08291|1|0.0|1156|mmu:14772|G protein-coupled receptor kinase [EC:2.7.11.16] GO:0043005//neuron projection;GO:0044297//cell body;GO:0044444//cytoplasmic part;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044444//cytoplasmic part GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0004518//nuclease activity GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006898//receptor-mediated endocytosis;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006898//receptor-mediated endocytosis gi|124001568|ref|NP_062370.2|/0/G protein-coupled receptor kinase 4 isoform 1 [Mus musculus] 110532 6607.29 8.18 7.266666667 -0.170807114 Down 0.29085336 Adarb1 "adenosine deaminase, RNA-specific, B1" K13194|1|0.0|1238|mmu:110532|double stranded RNA-specific editase B [EC:3.5.-.-] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0004000//adenosine deaminase activity;GO:0043169//cation binding;GO:0003723//RNA binding;GO:0004000//adenosine deaminase activity;GO:0043169//cation binding;GO:0003723//RNA binding;GO:0004000//adenosine deaminase activity;GO:0043169//cation binding;GO:0003723//RNA binding;GO:0004000//adenosine deaminase activity;GO:0043169//cation binding;GO:0003723//RNA binding GO:0016553//base conversion or substitution editing;GO:0006469//negative regulation of protein kinase activity;GO:0019079//viral genome replication;GO:0008283//cell proliferation;GO:0006396//RNA processing;GO:0016477//cell migration;GO:0007049//cell cycle;GO:0016553//base conversion or substitution editing;GO:0006469//negative regulation of protein kinase activity;GO:0019079//viral genome replication;GO:0008283//cell proliferation;GO:0006396//RNA processing;GO:0016477//cell migration;GO:0007049//cell cycle;GO:0016553//base conversion or substitution editing;GO:0006469//negative regulation of protein kinase activity;GO:0019079//viral genome replication;GO:0008283//cell proliferation;GO:0006396//RNA processing;GO:0016477//cell migration;GO:0007049//cell cycle;GO:0016553//base conversion or substitution editing;GO:0006469//negative regulation of protein kinase activity;GO:0019079//viral genome replication;GO:0008283//cell proliferation;GO:0006396//RNA processing;GO:0016477//cell migration;GO:0007049//cell cycle gi|568966341|ref|XP_006513126.1|/0/PREDICTED: double-stranded RNA-specific editase 1 isoform X3 [Mus musculus] 81702 9408.39 11.52333333 10.35666667 -0.153998362 Down 0.29085336 Ankrd17 ankyrin repeat domain 17 K16726|1|0.0|3497|ssc:100520501|ankyrin repeat domain-containing protein 17 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0001568//blood vessel development;GO:0051145//smooth muscle cell differentiation "gi|148673380|gb|EDL05327.1|/0/ankyrin repeat domain 17, isoform CRA_d, partial [Mus musculus]" 11761 4382 7.246666667 8.16 0.171251618 Up 0.29085336 Aox1 aldehyde oxidase 1 K00157|1|0.0|2634|mmu:11761|aldehyde oxidase [EC:1.2.3.1] GO:0044444//cytoplasmic part "GO:0046914//transition metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0016623;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0050662//coenzyme binding;GO:0000166//nucleotide binding" GO:0044237//cellular metabolic process;GO:0044710 gi|110347467|ref|NP_033806.2|/0/aldehyde oxidase 1 [Mus musculus] 100383 2684 35.18666667 38.11333333 0.11526694 Up 0.29085336 Bsdc1 BSD domain containing 1 - - - - gi|31981603|ref|NP_598650.2|/0/BSD domain-containing protein 1 [Mus musculus] 75600 861 0.193333333 0.423333333 1.130703692 Up 0.290815751 Calml4 calmodulin-like 4 K02183|1|3e-17|90.9|sko:100374593|calmodulin - - - "gi|148694085|gb|EDL26032.1|/2.23645e-91/calmodulin-like 4, isoform CRA_c [Mus musculus]" 24066 4611 6.943333333 6.116666667 -0.182882776 Down 0.290768739 Spry4 sprouty homolog 4 (Drosophila) K17385|1|5e-149|531|mmu:24066|protein sprouty homolog 4 GO:0044424 GO:0005488//binding GO:0032502//developmental process;GO:0043405//regulation of MAP kinase activity gi|676262404|gb|KFO19378.1|/1.33248e-150/Protein sprouty like protein 4 [Fukomys damarensis] 69749 440 6.056666667 5.296666667 -0.193439295 Down 0.290759337 Epb41l4aos "erythrocyte membrane protein band 4.1 like 4a, opposite strand" - - - - gi|148664658|gb|EDK97074.1|/1.94351e-14/mCG121507 [Mus musculus] 230577 2235.86 3.363333333 2.826666667 -0.250790005 Down 0.290721727 Pars2 prolyl-tRNA synthetase (mitochondrial)(putative) K01881|1|0.0|964|mmu:230577|prolyl-tRNA synthetase [EC:6.1.1.15] GO:0044429;GO:0044429;GO:0044429;GO:0044429 GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation "gi|139948914|ref|NP_001077356.1|/0/probable proline--tRNA ligase, mitochondrial isoform 2 [Mus musculus]" 69159 1227 1.256666667 0.906666667 -0.470957872 Down 0.290721727 Rhebl1 Ras homolog enriched in brain like 1 K07849|1|4e-100|367|mmu:69159|Ras homolog enriched in brain like 1 GO:0016020//membrane;GO:0044424 GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction gi|21312218|ref|NP_081243.1|/3.06783e-99/GTPase RhebL1 precursor [Mus musculus] 381510 2984 1.24 0.893333333 -0.473069621 Down 0.290721727 Dpy19l4 dpy-19-like 4 (C. elegans) - - - - - 19820 7435 2.84 3.38 0.251132317 Up 0.290721727 Rlim "ring finger protein, LIM domain interacting" K16271|1|0.0|654|mmu:19820|E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0044092//negative regulation of molecular function;GO:0032446//protein modification by small protein conjugation;GO:0019941//modification-dependent protein catabolic process;GO:0009048//dosage compensation by inactivation of X chromosome;GO:0006366//transcription from RNA polymerase II promoter gi|47078289|ref|NP_035406.3|/0/E3 ubiquitin-protein ligase RLIM [Mus musculus] 192199 1834 0.433333333 0.2 -1.115477217 Down 0.290646508 Rspo1 R-spondin 1 K19471|1|7e-144|513|mmu:192199|R-spondin-1 GO:0043231//intracellular membrane-bounded organelle;GO:0044421 GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding GO:0007126//meiotic nuclear division;GO:0030177//positive regulation of Wnt signaling pathway;GO:0002176//male germ cell proliferation;GO:0010467//gene expression gi|227452351|ref|NP_619624.2|/5.96977e-143/R-spondin-1 precursor [Mus musculus] 18783 2869 0.923333333 0.613333333 -0.59018021 Down 0.290637106 Pla2g4a "phospholipase A2, group IVA (cytosolic, calcium-dependent)" K16342|1|0.0|1516|mmu:18783|cytosolic phospholipase A2 [EC:3.1.1.4] GO:0030141//secretory granule;GO:0030141//secretory granule GO:0005543//phospholipid binding;GO:0046872//metal ion binding;GO:0004623//phospholipase A2 activity;GO:0005543//phospholipid binding;GO:0046872//metal ion binding;GO:0004623//phospholipase A2 activity GO:0006906//vesicle fusion;GO:0006915//apoptotic process;GO:0001660//fever generation;GO:0030282//bone mineralization;GO:0001676//long-chain fatty acid metabolic process;GO:0001893//maternal placenta development;GO:0031960//response to corticosteroid;GO:0046677//response to antibiotic;GO:0001516//prostaglandin biosynthetic process;GO:0048875//chemical homeostasis within a tissue;GO:0000302//response to reactive oxygen species;GO:0002237//response to molecule of bacterial origin;GO:0010038//response to metal ion;GO:0008283//cell proliferation;GO:0008585//female gonad development;GO:0015909//long-chain fatty acid transport;GO:0006644//phospholipid metabolic process;GO:0006906//vesicle fusion;GO:0006915//apoptotic process;GO:0001660//fever generation;GO:0030282//bone mineralization;GO:0001676//long-chain fatty acid metabolic process;GO:0001893//maternal placenta development;GO:0031960//response to corticosteroid;GO:0046677//response to antibiotic;GO:0001516//prostaglandin biosynthetic process;GO:0048875//chemical homeostasis within a tissue;GO:0000302//response to reactive oxygen species;GO:0002237//response to molecule of bacterial origin;GO:0010038//response to metal ion;GO:0008283//cell proliferation;GO:0008585//female gonad development;GO:0015909//long-chain fatty acid transport;GO:0006644//phospholipid metabolic process gi|779176837|ref|NP_001292561.1|/0/cytosolic phospholipase A2 isoform 2 [Mus musculus] 68126 1242 14.84666667 13.45 -0.142532885 Down 0.290608898 Fahd2a fumarylacetoacetate hydrolase domain containing 2A K01557|1|8e-34|147|cin:100175822|acylpyruvate hydrolase [EC:3.7.1.5] GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity;GO:0043169//cation binding - "gi|148696242|gb|EDL28189.1|/4.54677e-175/fumarylacetoacetate hydrolase domain containing 2A, isoform CRA_a, partial [Mus musculus]" 216021 3102 0.673333333 0.396666667 -0.763393719 Down 0.290571289 Stox1 storkhead box 1 - GO:0031981//nuclear lumen - - gi|198278492|ref|NP_001028432.1|/0/storkhead-box protein 1 [Mus musculus] 207854 820 0.41 0.693333333 0.757925213 Up 0.290571289 Fmr1nb fragile X mental retardation 1 neighbor - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|262231754|ref|NP_001160091.1|/7.51851e-86/fragile X mental retardation 1 neighbor protein isoform 2 [Mus musculus] 15064 2509 4.003333333 3.413333333 -0.230020436 Down 0.290524277 Mr1 "major histocompatibility complex, class I-related" "K06751|1|1e-73|280|acs:100559582|major histocompatibility complex, class I" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0042611 GO:0004888//transmembrane signaling receptor activity GO:0042742//defense response to bacterium;GO:0032612//interleukin-1 production;GO:0048002//antigen processing and presentation of peptide antigen gi|6680157|ref|NP_032235.1|/0/major histocompatibility complex class I-related gene protein precursor [Mus musculus] 217011 1771 3.383333333 3.976666667 0.233114316 Up 0.290524277 Nle1 notchless homolog 1 (Drosophila) K14855|1|0.0|943|mmu:217011|ribosome assembly protein 4 GO:0031981//nuclear lumen - GO:0007166//cell surface receptor signaling pathway;GO:0001825//blastocyst formation gi|238624156|ref|NP_663406.2|/0/notchless protein homolog 1 [Mus musculus] 64898 5651 1.636666667 2.063333333 0.334216385 Up 0.290486667 Lpin2 lipin 2 K15728|1|0.0|1654|mmu:64898|phosphatidate phosphatase LPIN [EC:3.1.3.4] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane GO:0016791//phosphatase activity;GO:0016791//phosphatase activity GO:0032787//monocarboxylic acid metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0032787//monocarboxylic acid metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006366//transcription from RNA polymerase II promoter gi|259089106|ref|NP_001158357.1|/0/phosphatidate phosphatase LPIN2 isoform 1 [Mus musculus] 108937 7157 1.67 2.103333333 0.332829402 Up 0.290486667 Rnf169 ring finger protein 169 - - - - gi|255003678|ref|NP_780597.2|/0/E3 ubiquitin-protein ligase RNF169 [Mus musculus] 100041953 801 114.2566667 123.4133333 0.111219922 Up 0.290383241 Gm10094 Sin3-associated polypeptide 18B K14324|1|2e-87|324|rno:290284|histone deacetylase complex subunit SAP18 GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane - "GO:0006351//transcription, DNA-templated" gi|215490074|ref|NP_033145.2|/1.44659e-86/histone deacetylase complex subunit SAP18 [Mus musculus] 26569 4008 10.50666667 11.67 0.151499527 Up 0.290308022 Slc27a4 "solute carrier family 27 (fatty acid transporter), member 4" "K08745|1|0.0|1276|mmu:26569|solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005903//brush border;GO:0031090//organelle membrane GO:0015645//fatty acid ligase activity;GO:0005319//lipid transporter activity;GO:0036094//small molecule binding GO:0000038//very long-chain fatty acid metabolic process;GO:0044763;GO:0031667//response to nutrient levels;GO:0008544//epidermis development;GO:0015909//long-chain fatty acid transport gi|45597453|ref|NP_036119.1|/0/long-chain fatty acid transport protein 4 [Mus musculus] 108086 4601.21 11.39 10.23333333 -0.154491592 Down 0.290308022 Rnf216 ring finger protein 216 K11976|1|0.0|1555|mmu:108086|TRIAD3; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.27] GO:0044424 GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0012501//programmed cell death;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0032479//regulation of type I interferon production;GO:0000209//protein polyubiquitination;GO:0050688//regulation of defense response to virus gi|300863078|ref|NP_996993.1|/0/E3 ubiquitin-protein ligase RNF216 isoform B [Mus musculus] 26364 3149.61 35.58 32.73 -0.120452908 Down 0.29029862 Adgre5 adhesion G protein-coupled receptor E5 K08446|1|0.0|1317|mmu:26364|CD97 antigen - - - - 26395 2387 19.13666667 20.96666667 0.131757961 Up 0.290289217 Map2k1 mitogen-activated protein kinase kinase 1 K04368|1|0.0|712|mmu:26395|mitogen-activated protein kinase kinase 1 [EC:2.7.12.2] GO:0030424//axon;GO:0000922//spindle pole;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0016020//membrane;GO:0005768//endosome;GO:0005924//cell-substrate adherens junction GO:0031267//small GTPase binding;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0032550;GO:0019901//protein kinase binding;GO:0004725//protein tyrosine phosphatase activity;GO:0030295//protein kinase activator activity GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0031175//neuron projection development;GO:0043408//regulation of MAPK cascade;GO:0006940//regulation of smooth muscle contraction;GO:0031960//response to corticosteroid;GO:0007569//cell aging;GO:0016477//cell migration;GO:0032401//establishment of melanosome localization;GO:0000087//mitotic M phase;GO:0001892//embryonic placenta development;GO:0006935//chemotaxis;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0032386//regulation of intracellular transport;GO:0033043//regulation of organelle organization;GO:0051259//protein oligomerization;GO:0007030//Golgi organization;GO:0038127//ERBB signaling pathway;GO:0009913//epidermal cell differentiation;GO:0001568//blood vessel development;GO:0045860//positive regulation of protein kinase activity;GO:0022408//negative regulation of cell-cell adhesion;GO:0009611//response to wounding gi|7670399|dbj|BAA95051.1|/0/unnamed protein product [Mus musculus] 380959 3727 1.516666667 1.14 -0.41187022 Down 0.290195194 Alg10b "asparagine-linked glycosylation 10B (alpha-1,2-glucosyltransferase)" "K03850|1|0.0|912|mmu:380959|alpha-1,2-glucosyltransferase [EC:2.4.1.256]" GO:0031224//intrinsic component of membrane "GO:0016757//transferase activity, transferring glycosyl groups;GO:0016247//channel regulator activity" - "gi|85701951|ref|NP_001028613.1|/0/putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase [Mus musculus]" 228880 3513.37 32.19 35.02333333 0.121703821 Up 0.290166986 Zmynd8 "zinc finger, MYND-type containing 8" K20289|1|6e-23|113|smm:Smp_143570|conserved oligomeric Golgi complex subunit 2;K08883|3|2e-16|91.7|bfo:BRAFLDRAFT_240330|tripartite motif-containing protein 33 [EC:2.3.2.27];K08881|5|7e-16|90.1|cge:100771974|tripartite motif-containing protein 24 [EC:2.3.2.27] - - - - 14184 4075.23 5.516666667 4.813333333 -0.196760475 Down 0.290129377 Fgfr3 fibroblast growth factor receptor 3 K05094|1|0.0|1376|tup:102500041|fibroblast growth factor receptor 3 [EC:2.7.10.1] GO:0000323//lytic vacuole;GO:0031982//vesicle;GO:0044459;GO:0016021//integral component of membrane;GO:0000323//lytic vacuole;GO:0031982//vesicle;GO:0044459;GO:0016021//integral component of membrane;GO:0000323//lytic vacuole;GO:0031982//vesicle;GO:0044459;GO:0016021//integral component of membrane;GO:0000323//lytic vacuole;GO:0031982//vesicle;GO:0044459;GO:0016021//integral component of membrane GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0032550;GO:0019838//growth factor binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0032550;GO:0019838//growth factor binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0032550;GO:0019838//growth factor binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0032550;GO:0019838//growth factor binding GO:0007224//smoothened signaling pathway;GO:0001935//endothelial cell proliferation;GO:0042490//mechanoreceptor differentiation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0006915//apoptotic process;GO:0014003//oligodendrocyte development;GO:0016567//protein ubiquitination;GO:0043410//positive regulation of MAPK cascade;GO:0045686//negative regulation of glial cell differentiation;GO:0007409//axonogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0060428//lung epithelium development;GO:0060348//bone development;GO:0048729//tissue morphogenesis;GO:0002088//lens development in camera-type eye;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0010517//regulation of phospholipase activity;GO:0030855//epithelial cell differentiation;GO:0021539//subthalamus development;GO:0043583//ear development;GO:0045926//negative regulation of growth;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0019827//stem cell population maintenance;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0007067//mitotic nuclear division;GO:0009611//response to wounding;GO:0007224//smoothened signaling pathway;GO:0001935//endothelial cell proliferation;GO:0042490//mechanoreceptor differentiation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0006915//apoptotic process;GO:0014003//oligodendrocyte development;GO:0016567//protein ubiquitination;GO:0043410//positive regulation of MAPK cascade;GO:0045686//negative regulation of glial cell differentiation;GO:0007409//axonogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0060428//lung epithelium development;GO:0060348//bone development;GO:0048729//tissue morphogenesis;GO:0002088//lens development in camera-type eye;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0010517//regulation of phospholipase activity;GO:0030855//epithelial cell differentiation;GO:0021539//subthalamus development;GO:0043583//ear development;GO:0045926//negative regulation of growth;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0019827//stem cell population maintenance;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0007067//mitotic nuclear division;GO:0009611//response to wounding;GO:0007224//smoothened signaling pathway;GO:0001935//endothelial cell proliferation;GO:0042490//mechanoreceptor differentiation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0006915//apoptotic process;GO:0014003//oligodendrocyte development;GO:0016567//protein ubiquitination;GO:0043410//positive regulation of MAPK cascade;GO:0045686//negative regulation of glial cell differentiation;GO:0007409//axonogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0060428//lung epithelium development;GO:0060348//bone development;GO:0048729//tissue morphogenesis;GO:0002088//lens development in camera-type eye;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0010517//regulation of phospholipase activity;GO:0030855//epithelial cell differentiation;GO:0021539//subthalamus development;GO:0043583//ear development;GO:0045926//negative regulation of growth;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0019827//stem cell population maintenance;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0007067//mitotic nuclear division;GO:0009611//response to wounding;GO:0007224//smoothened signaling pathway;GO:0001935//endothelial cell proliferation;GO:0042490//mechanoreceptor differentiation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0006915//apoptotic process;GO:0014003//oligodendrocyte development;GO:0016567//protein ubiquitination;GO:0043410//positive regulation of MAPK cascade;GO:0045686//negative regulation of glial cell differentiation;GO:0007409//axonogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0060428//lung epithelium development;GO:0060348//bone development;GO:0048729//tissue morphogenesis;GO:0002088//lens development in camera-type eye;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0010517//regulation of phospholipase activity;GO:0030855//epithelial cell differentiation;GO:0021539//subthalamus development;GO:0043583//ear development;GO:0045926//negative regulation of growth;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0019827//stem cell population maintenance;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0007067//mitotic nuclear division;GO:0009611//response to wounding gi|254028254|ref|NP_001156689.1|/0/fibroblast growth factor receptor 3 isoform 3 precursor [Mus musculus] 54197 1101 31.32 34.12 0.123533434 Up 0.289969536 Rnf5 ring finger protein 5 K10666|1|2e-84|314|rno:407784|E3 ubiquitin-protein ligase RNF5 [EC:2.3.2.27] GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0005740//mitochondrial envelope GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination;GO:0006515//misfolded or incompletely synthesized protein catabolic process gi|9507059|ref|NP_062276.1|/1.99121e-83/E3 ubiquitin-protein ligase RNF5 [Mus musculus] 56299 1173 8.243333333 7.34 -0.167447771 Down 0.289922524 Fkbpl FK506 binding protein-like K20097|1|5e-178|625|mmu:56299|FK506-binding protein-like - - - - 68971 1183 8.113333333 7.216666667 -0.168962143 Down 0.289922524 Tamm41 TAM41 mitochondrial translocator assembly and maintenance homolog K17807|1|0.0|674|mmu:68971|mitochondrial translocator assembly and maintenance protein 41 GO:0043231//intracellular membrane-bounded organelle - GO:0045184//establishment of protein localization "gi|76559944|ref|NP_081170.1|/0/phosphatidate cytidylyltransferase, mitochondrial precursor [Mus musculus]" 16716 5455 2.086666667 2.556666667 0.293063921 Up 0.28990372 Ky kyphoscoliosis peptidase K14786|1|4e-24|117|smm:Smp_133510|protein KRI1 - - - "gi|148689102|gb|EDL21049.1|/0/kyphoscoliosis peptidase, isoform CRA_a, partial [Mus musculus]" 68038 4210.79 6.273333333 7.09 0.176553405 Up 0.28986611 Chid1 chitinase domain containing 1 K17525|1|5e-127|458|mmu:68038|chitinase domain-containing protein 1 GO:0000323//lytic vacuole;GO:0000323//lytic vacuole "GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds" GO:0006952//defense response;GO:0044238//primary metabolic process;GO:0006026;GO:0006952//defense response;GO:0044238//primary metabolic process;GO:0006026 gi|537199682|gb|ERE79071.1|/1.98921e-171/chitinase domain-containing protein 1 [Cricetulus griseus] 207425 4566 7.003333333 6.183333333 -0.179656975 Down 0.28986611 Wdr11 WD repeat domain 11 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|227908800|ref|NP_758459.2|/0/WD repeat-containing protein 11 [Mus musculus] 14163 4166 5.226666667 5.976666667 0.193449929 Up 0.28986611 Fgd1 "FYVE, RhoGEF and PH domain containing 1" "K05720|1|0.0|1656|mmu:14163|FYVE, RhoGEF and PH domain containing 1" GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031252//cell leading edge;GO:0043232;GO:0044444//cytoplasmic part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0051020//GTPase binding;GO:0043169//cation binding;GO:0008289//lipid binding GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis;GO:0012501//programmed cell death;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030031//cell projection assembly "gi|31982367|ref|NP_032027.2|/0/FYVE, RhoGEF and PH domain-containing protein 1 [Mus musculus]" 71963 2432 3.166666667 3.73 0.236210618 Up 0.289828501 Cdca4 cell division cycle associated 4 - GO:0043231//intracellular membrane-bounded organelle - - gi|27229143|ref|NP_082299.1|/7.416e-131/cell division cycle-associated protein 4 [Mus musculus] 12156 3566 0.506666667 0.256666667 -0.981140973 Down 0.289809696 Bmp2 bone morphogenetic protein 2 K04662|1|0.0|744|mmu:12156|bone morphogenetic protein 2/4 GO:0032991//macromolecular complex;GO:0031982//vesicle;GO:0044424;GO:0044421 "GO:0070696//transmembrane receptor protein serine/threonine kinase binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0008047//enzyme activator activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity" GO:0001935//endothelial cell proliferation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0006915//apoptotic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0001501//skeletal system development;GO:0030282//bone mineralization;GO:0051154//negative regulation of striated muscle cell differentiation;GO:0048754//branching morphogenesis of an epithelial tube;GO:0009952//anterior/posterior pattern specification;GO:0043009//chordate embryonic development;GO:0045687//positive regulation of glial cell differentiation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0006952//defense response;GO:0014070//response to organic cyclic compound;GO:0051726//regulation of cell cycle;GO:0003306//Wnt signaling pathway involved in heart development;GO:0021984//adenohypophysis development;GO:0043410//positive regulation of MAPK cascade;GO:0035051//cardiocyte differentiation;GO:0001837//epithelial to mesenchymal transition;GO:0016477//cell migration;GO:0003134;GO:0001934//positive regulation of protein phosphorylation;GO:0032342//aldosterone biosynthetic process;GO:0033993//response to lipid;GO:0003171//atrioventricular valve development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0001649//osteoblast differentiation;GO:0009605//response to external stimulus;GO:0031947//negative regulation of glucocorticoid biosynthetic process;GO:0030182//neuron differentiation;GO:0001657//ureteric bud development;GO:0009968//negative regulation of signal transduction;GO:0044702//single organism reproductive process;GO:0071363//cellular response to growth factor stimulus;GO:0043583//ear development;GO:0010921//regulation of phosphatase activity;GO:0009100//glycoprotein metabolic process;GO:0031647//regulation of protein stability gi|71896669|ref|NP_031579.2|/0/bone morphogenetic protein 2 preproprotein [Mus musculus] 26554 4935 20.66666667 18.86333333 -0.131721078 Down 0.289725074 Cul3 cullin 3 K03869|1|0.0|1492|mmu:26554|cullin 3 - - - - 67610 3849 3.1 2.59 -0.259316118 Down 0.289715672 Rspry1 ring finger and SPRY domain containing 1 K12169|1|2e-19|101|dan:Dana_GF17158|Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27] - GO:0046914//transition metal ion binding - gi|165972349|ref|NP_080550.3|/0/RING finger and SPRY domain-containing protein 1 precursor [Mus musculus] 12258 1837 100.8933333 109.2166667 0.114362181 Up 0.289696867 Serping1 "serine (or cysteine) peptidase inhibitor, clade G, member 1" K04001|1|0.0|974|mmu:12258|C1 inhibitor - - - gi|163914390|ref|NP_033906.2|/0/plasma protease C1 inhibitor precursor [Mus musculus] 18709 3159 13.58333333 14.95333333 0.138629561 Up 0.289555831 Pik3r2 "phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)" "K02649|1|0.0|1191|mmu:18709|phosphoinositide-3-kinase, regulatory subunit" GO:0043234//protein complex;GO:0044464 GO:0019207//kinase regulator activity;GO:0005102//receptor binding;GO:0052742 GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006661//phosphatidylinositol biosynthetic process;GO:0016310//phosphorylation gi|244792921|ref|NP_032867.2|/0/phosphatidylinositol 3-kinase regulatory subunit beta [Mus musculus] 229524 1825 13.29666667 14.66666667 0.1414764 Up 0.289555831 Msto1 "misato 1, mitochondrial distribution and morphology regulator" K17408|1|5e-136|487|asn:102387036|small subunit ribosomal protein S29 GO:0032991//macromolecular complex;GO:0031966//mitochondrial membrane GO:0032550 GO:0007005//mitochondrion organization;GO:0043623//cellular protein complex assembly gi|254692960|ref|NP_659147.2|/0/protein misato homolog 1 [Mus musculus] 100272221 1405 0.323333333 0.11 -1.555518723 Down 0.289546429 Gm17801 "predicted gene, 17801" - - - - gi|672066800|ref|XP_008765771.1|/9.36812e-10/PREDICTED: SUMO-conjugating enzyme UBC9 isoform X2 [Rattus norvegicus] 19208 1283 0.16 0.376666667 1.235216462 Up 0.289358381 Ptcra pre T cell antigen receptor alpha K06056|1|2e-105|385|mmu:19208|pre T-cell antigen receptor alpha GO:0031224//intrinsic component of membrane - GO:0070233//negative regulation of T cell apoptotic process gi|6755216|ref|NP_035325.1|/1.50889e-104/pre T-cell antigen receptor alpha precursor [Mus musculus] 102443351 4506 0.2 0.426666667 1.093109404 Up 0.289311369 Xntrpc "Xndc1-transient receptor potential cation channel, subfamily C, member 2 readthrough" K04965|1|0.0|1852|cge:100689218|transient receptor potential cation channel subfamily C member 2 GO:0044425;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0005262//calcium channel activity;GO:0005488//binding GO:0044763;GO:0002118//aggressive behavior;GO:0007617//mating behavior gi|154090945|ref|NP_035774.2|/0/Xndr-Trpc2 readthrough [Mus musculus] 73469 4959 4.753333333 4.1 -0.213315666 Down 0.289283162 Rnf38 ring finger protein 38 K19041|1|0.0|772|mmu:73469|E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27] GO:0031514//motile cilium GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - gi|56749656|sp|Q8BI21.1|RNF38_MOUSE/0/RecName: Full=E3 ubiquitin-protein ligase RNF38; AltName: Full=RING finger protein 38 70144 5760.84 4.83 4.176666667 -0.20967118 Down 0.289283162 Lrch3 leucine-rich repeats and calponin homology (CH) domain containing 3 K10130|1|5e-23|114|sko:102800700|leucine-rich repeats and death domain-containing protein;K19613|5|1e-21|109|cbr:CBG19995|leucine-rich repeat protein SHOC2 - - - gi|891713352|ref|NP_001297602.1|/0/leucine-rich repeat and calponin homology domain-containing protein 3 isoform 3 [Mus musculus] 18021 6032 4.83 4.176666667 -0.20967118 Down 0.289283162 Nfatc3 "nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3" "K17333|1|0.0|1895|mmu:18021|nuclear factor of activated T-cells, cytoplasmic 3" GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0044444//cytoplasmic part GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding GO:0001525//angiogenesis;GO:0015980//energy derivation by oxidation of organic compounds;GO:0006366//transcription from RNA polymerase II promoter;GO:0042692//muscle cell differentiation;GO:0010226//response to lithium ion "gi|113199769|ref|NP_035031.2|/0/nuclear factor of activated T-cells, cytoplasmic 3 [Mus musculus]" 27277 2819.02 11.47333333 10.33333333 -0.150978882 Down 0.289264357 Golga5 "golgi autoantigen, golgin subfamily a, 5" K09291|1|2e-23|114|mze:101481741|nucleoprotein TPR GO:0031224//intrinsic component of membrane;GO:0030137//COPI-coated vesicle;GO:0031985//Golgi cisterna;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0030137//COPI-coated vesicle;GO:0031985//Golgi cisterna;GO:0012505//endomembrane system GO:0017016//Ras GTPase binding;GO:0042802//identical protein binding;GO:0017016//Ras GTPase binding;GO:0042802//identical protein binding GO:0006996//organelle organization;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006996//organelle organization;GO:0006891//intra-Golgi vesicle-mediated transport "gi|148686914|gb|EDL18861.1|/0/golgi autoantigen, golgin subfamily a, 5, isoform CRA_a, partial [Mus musculus]" 13167 587 99.61333333 107.4333333 0.109030921 Up 0.289245553 Dbi diazepam binding inhibitor "K08762|1|7e-44|178|mmu:13167|diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein)" GO:0016020//membrane;GO:0043232;GO:0044421;GO:0030136//clathrin-coated vesicle GO:0005102//receptor binding;GO:0043168//anion binding GO:0006732;GO:0006635//fatty acid beta-oxidation;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0008544//epidermis development;GO:0008202//steroid metabolic process;GO:0007417//central nervous system development;GO:0008610//lipid biosynthetic process;GO:0007589//body fluid secretion;GO:0006639//acylglycerol metabolic process;GO:0008283//cell proliferation;GO:0050804//modulation of synaptic transmission;GO:0007584//response to nutrient gi|6681137|ref|NP_031856.1|/4.77762e-43/acyl-CoA-binding protein isoform 2 [Mus musculus] 66208 658 98.14 105.8833333 0.109562342 Up 0.289189138 Nenf neuron derived neurotrophic factor K17278|1|1e-10|68.6|pxy:105389104|membrane-associated progesterone receptor component GO:0044421 GO:0046906//tetrapyrrole binding;GO:0043169//cation binding;GO:0005102//receptor binding GO:0000165//MAPK cascade gi|13384818|ref|NP_079700.1|/7.49437e-68/neudesin precursor [Mus musculus] 70611 3446 1.516666667 1.926666667 0.345202947 Up 0.289151529 Fbxo33 F-box protein 33 K10310|1|0.0|947|mmu:70611|F-box protein 33 - - GO:0032446//protein modification by small protein conjugation "gi|148704730|gb|EDL36677.1|/0/mCG20838, isoform CRA_a, partial [Mus musculus]" 72425 2883 1.703333333 1.313333333 -0.375127661 Down 0.289151529 Katnbl1 katanin p80 subunit B like 1 K18643|1|2e-09|67.4|tru:101065628|katanin p80 WD40 repeat-containing subunit B1 GO:0031981//nuclear lumen - - gi|21312290|ref|NP_077216.1|/3.18794e-168/KATNB1-like protein 1 [Mus musculus] 27388 2172 13.72 15.08 0.136355947 Up 0.289151529 Ptdss2 phosphatidylserine synthase 2 K08730|1|0.0|893|mmu:27388|phosphatidylserine synthase 2 [EC:2.7.8.29] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0017169//CDP-alcohol phosphatidyltransferase activity GO:0006658//phosphatidylserine metabolic process gi|31560497|ref|NP_038810.2|/0/phosphatidylserine synthase 2 [Mus musculus] 75219 4632 30.44 33.15 0.123040511 Up 0.289132724 Dusp18 dual specificity phosphatase 18 K14165|1|8e-103|378|mmu:75219|atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] - - - "gi|148708497|gb|EDL40444.1|/6.87812e-147/dual specificity phosphatase 18, partial [Mus musculus]" 67391 3261 31.2 33.91 0.120164755 Up 0.289132724 Fundc2 FUN14 domain containing 2 K17986|1|2e-48|197|lcm:102361682|FUN14 domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle - - gi|262050556|ref|NP_080402.3|/1.29731e-72/FUN14 domain-containing protein 2 [Mus musculus] 228913 5670 3.26 2.733333333 -0.254210555 Down 0.289048103 Zfp217 zinc finger protein 217 K09228|1|3e-23|114|gja:107109176|KRAB domain-containing zinc finger protein GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0000975//regulatory region DNA binding;GO:0000975//regulatory region DNA binding "GO:0007568//aging;GO:0006351//transcription, DNA-templated;GO:0007568//aging;GO:0006351//transcription, DNA-templated" gi|75677492|ref|NP_001028471.1|/0/zinc finger protein 217 [Mus musculus] 214968 5697.78 5.303333333 4.61 -0.202132679 Down 0.28887886 Sema6d "sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D" K06842|1|0.0|1886|fca:101100893|semaphorin 6 GO:0031224//intrinsic component of membrane GO:0005102//receptor binding GO:0048731//system development;GO:0048869//cellular developmental process gi|40385869|ref|NP_766125.2|/0/semaphorin-6D isoform Sema6D-1 precursor [Mus musculus] 19352 1340.25 30.53 33.21 0.121390133 Up 0.288869457 Rabggtb "Rab geranylgeranyl transferase, b subunit" K05956|1|0.0|702|mmu:19352|geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60] - GO:0004661//protein geranylgeranyltransferase activity;GO:0043169//cation binding;GO:0004661//protein geranylgeranyltransferase activity;GO:0043169//cation binding;GO:0004661//protein geranylgeranyltransferase activity;GO:0043169//cation binding;GO:0004661//protein geranylgeranyltransferase activity;GO:0043169//cation binding;GO:0004661//protein geranylgeranyltransferase activity;GO:0043169//cation binding;GO:0004661//protein geranylgeranyltransferase activity;GO:0043169//cation binding;GO:0004661//protein geranylgeranyltransferase activity;GO:0043169//cation binding;GO:0004661//protein geranylgeranyltransferase activity;GO:0043169//cation binding GO:0018342//protein prenylation;GO:0018342//protein prenylation;GO:0018342//protein prenylation;GO:0018342//protein prenylation;GO:0018342//protein prenylation;GO:0018342//protein prenylation;GO:0018342//protein prenylation;GO:0018342//protein prenylation gi|254553291|ref|NP_035361.2|/2.03066e-158/geranylgeranyl transferase type-2 subunit beta isoform 1 [Mus musculus] 76895 4671.12 33.84333333 31.16 -0.119176438 Down 0.288869457 Bicd2 bicaudal D homolog 2 (Drosophila) K18739|1|0.0|1389|mmu:76895|protein bicaudal D - - - - 20624 3397 13.31333333 14.66 0.139013271 Up 0.288860055 Eftud2 elongation factor Tu GTP binding domain containing 2 K12852|1|0.0|1894|mmu:20624|116 kDa U5 small nuclear ribonucleoprotein component GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0005681//spliceosomal complex;GO:0016604//nuclear body "GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008135//translation factor activity, RNA binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008135//translation factor activity, RNA binding" GO:0006412//translation;GO:0000377;GO:0009154//purine ribonucleotide catabolic process;GO:0006412//translation;GO:0000377;GO:0009154//purine ribonucleotide catabolic process gi|795155319|ref|XP_011795512.1|/0/PREDICTED: 116 kDa U5 small nuclear ribonucleoprotein component isoform X1 [Colobus angolensis palliatus] 11431 3107 8.366666667 9.363333333 0.16236926 Up 0.288813043 Acp1 "acid phosphatase 1, soluble" K14394|1|1e-88|330|mmu:102642088|low molecular weight phosphotyrosine protein phosphatase [EC:3.1.3.2 3.1.3.48] - - - - 70823 3948.7 3.91 3.33 -0.23164643 Down 0.288784836 Hmgxb4 HMG box domain containing 4 K11298|1|0.0|828|cge:100757455|high mobility group protein 2-like 1 GO:0031010//ISWI-type complex - - "gi|148678874|gb|EDL10821.1|/0/high mobility group box 2-like 1, isoform CRA_a, partial [Mus musculus]" 11910 1981 3.936666667 3.356666667 -0.229945281 Down 0.288784836 Atf3 activating transcription factor 3 K09032|1|1e-82|310|chx:102183991|activating transcription factor 3 - - - - 107986 1929 3.843333333 3.266666667 -0.234538859 Down 0.288784836 Ddb2 damage specific DNA binding protein 2 K10140|1|0.0|842|mmu:107986|DNA damage-binding protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex GO:0003676//nucleic acid binding;GO:0019787//ubiquitin-like protein transferase activity GO:0016567//protein ubiquitination;GO:0009416//response to light stimulus;GO:0006281//DNA repair gi|29150251|ref|NP_082395.2|/0/DNA damage-binding protein 2 [Mus musculus] 18545 473 0.116666667 0.326666667 1.485426827 Up 0.288719019 Pcp2 Purkinje cell protein 2 (L7) K15839|1|9e-11|67.8|pale:102885025|G-protein signaling modulator 1;K15837|2|1e-10|67.4|xtr:100380004|G-protein signaling modulator 2 GO:0044297//cell body;GO:0044297//cell body;GO:0044297//cell body GO:0060589;GO:0060589;GO:0060589 GO:0019222//regulation of metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0019222//regulation of metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0019222//regulation of metabolic process;GO:0007186//G-protein coupled receptor signaling pathway gi|193788667|ref|NP_001123275.1|/1.07269e-74/Purkinje cell protein 2 isoform 1 [Mus musculus] 77594 2496 0.316666667 0.573333333 0.856409146 Up 0.288672007 4930552P12Rik RIKEN cDNA 4930552P12 gene - - - - gi|148669791|gb|EDL01738.1|/2.55309e-44/mCG14272 [Mus musculus] 69519 1239 0.573333333 0.316666667 -0.856409146 Down 0.288672007 Rwdd2a RWD domain containing 2A - - - - gi|225543231|ref|NP_081376.2|/9.2254e-152/RWD domain-containing protein 2A [Mus musculus] 13345 1335 0.553333333 0.85 0.619314006 Up 0.288653202 Twist2 twist basic helix-loop-helix transcription factor 2 K09069|1|4e-86|320|aml:100478846|twist - - - - 14904 3444 18.83 20.58 0.128209982 Up 0.288606191 Gtpbp1 GTP binding protein 1 K14416|1|1e-06|58.5|hro:HELRODRAFT_101631|elongation factor 1 alpha-like protein GO:0044444//cytoplasmic part GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0009154//purine ribonucleotide catabolic process;GO:0006402//mRNA catabolic process gi|70778897|ref|NP_038846.2|/0/GTP-binding protein 1 [Mus musculus] 216154 3216.95 29.55 32.18666667 0.123305045 Up 0.288568581 Med16 mediator complex subunit 16 K15159|1|0.0|1699|mmu:216154|mediator of RNA polymerase II transcription subunit 16 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0010861//thyroid hormone receptor activator activity;GO:0008134//transcription factor binding;GO:0010861//thyroid hormone receptor activator activity;GO:0008134//transcription factor binding GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter gi|253970415|ref|NP_932775.2|/0/mediator of RNA polymerase II transcription subunit 16 isoform 1 [Mus musculus] 16980 3346 1.406666667 1.806666667 0.361049853 Up 0.288559179 Lrrn2 "leucine rich repeat protein 2, neuronal" K16351|1|7e-34|149|sko:100378039|netrin-G2 ligand;K16357|3|4e-32|143|amj:102575850|leucine-rich repeat and fibronectin type-III domain-containing protein 4 - - - "gi|148707720|gb|EDL39667.1|/0/leucine rich repeat protein 2, neuronal, isoform CRA_a, partial [Mus musculus]" 230789 3028.66 14.66 13.32333333 -0.137930031 Down 0.288493362 Fam76a "family with sequence similarity 76, member A" K20394|1|1e-134|483|fab:101820249|sestrin 2 - - - gi|21704090|ref|NP_663528.1|/9.31153e-150/protein FAM76A isoform A [Mus musculus] 100503380 1151 1.403333333 1.04 -0.432274204 Down 0.288465155 Snhg4 small nucleolar RNA host gene 4 - - - - - 13626 2060 7.256666667 8.136666667 0.165130888 Up 0.288455752 Eed embryonic ectoderm development K11462|1|0.0|877|ssc:100521029|polycomb protein EED GO:0031519//PcG protein complex;GO:0000803//sex chromosome GO:0005515//protein binding;GO:0008276//protein methyltransferase activity "GO:0006351//transcription, DNA-templated;GO:0031062//positive regulation of histone methylation;GO:0040029//regulation of gene expression, epigenetic" gi|2088637|gb|AAC53302.1|/0/embryonic ectoderm development protein [Mus musculus] 241112 2101 0.12 0.333333333 1.473931188 Up 0.288305314 Catip ciliogenesis associated TTC17 interacting protein K12347|1|6e-07|58.9|pss:102453799|natural resistance-associated macrophage protein - - - gi|85701842|ref|NP_001028517.1|/7.24986e-180/ciliogenesis-associated TTC17-interacting protein [Mus musculus] 74359 2585 2.356666667 2.843333333 0.270835527 Up 0.288286509 4931414P19Rik RIKEN cDNA 4931414P19 gene - - - - gi|28077031|ref|NP_083166.1|/0/uncharacterized protein C14orf93 homolog precursor [Mus musculus] 68671 1908 32.43 29.82333333 -0.120887508 Down 0.288239498 Pcyt2 "phosphate cytidylyltransferase 2, ethanolamine" K00967|1|0.0|832|mmu:68671|ethanolamine-phosphate cytidylyltransferase [EC:2.7.7.14] - GO:0070567 GO:0046337//phosphatidylethanolamine metabolic process gi|31980842|ref|NP_077191.2|/0/ethanolamine-phosphate cytidylyltransferase [Mus musculus] 76720 451 0.33 0.12 -1.459431619 Down 0.288230095 1700084D21Rik RIKEN cDNA 1700084D21 gene - - - - - 268281 6966 0.653333333 0.38 -0.78181983 Down 0.288173681 Shprh SNF2 histone linker PHD RING helicase K15710|1|0.0|3192|mmu:268281|E3 ubiquitin-protein ligase SHPRH [EC:3.6.4.- 2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0034728//nucleosome organization;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0034728//nucleosome organization;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0034728//nucleosome organization gi|118150662|ref|NP_001071175.1|/0/E3 ubiquitin-protein ligase SHPRH isoform a [Mus musculus] 74748 2040 0.21 0.436666667 1.056143078 Up 0.288154876 Slamf8 SLAM family member 8 K16853|1|1e-146|522|mmu:74748|SLAM family member 8 GO:0031224//intrinsic component of membrane - GO:0051341//regulation of oxidoreductase activity;GO:0006952//defense response;GO:0042493//response to drug;GO:0051452//intracellular pH reduction;GO:0042325//regulation of phosphorylation gi|110625804|ref|NP_083360.2|/1.12577e-145/SLAM family member 8 precursor [Mus musculus] 56348 1839 13.03666667 14.37 0.140485026 Up 0.288136071 Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 K10251|1|3e-166|587|mmu:56348|17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330] - - - - 50934 4064 3.11 3.663333333 0.2362424 Up 0.288089059 Slc7a8 "solute carrier family 7 (cationic amino acid transporter, y+ system), member 8" "K13781|1|0.0|948|mmu:50934|solute carrier family 7 (L-type amino acid transporter), member 8" GO:0016021//integral component of membrane;GO:0044459;GO:0044424 GO:0015171//amino acid transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0003823//antigen binding GO:0019752//carboxylic acid metabolic process;GO:0044763;GO:0055080//cation homeostasis;GO:0002376//immune system process;GO:0042221//response to chemical;GO:0007599//hemostasis;GO:0006812//cation transport;GO:0006865//amino acid transport gi|8394325|ref|NP_058668.1|/0/large neutral amino acids transporter small subunit 2 [Mus musculus] 140887 4543 6.76 5.963333333 -0.180904265 Down 0.288070255 Lnx2 ligand of numb-protein X 2 K10692|1|0.0|1338|mmu:140887|ligand of Numb protein X 1/2 [EC:2.3.2.27] - - - - 320080 5970 2.44 1.986666667 -0.296531318 Down 0.288004438 Zbtb39 zinc finger and BTB domain containing 39 K10511|1|0.0|1379|mmu:320080|zinc finger and BTB domain-containing protein 39 GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding - gi|37574147|ref|NP_932152.1|/0/zinc finger and BTB domain-containing protein 39 [Mus musculus] 99377 4472.41 0.956666667 1.303333333 0.446117871 Up 0.287995036 Sall4 sal-like 4 (Drosophila) K19871|1|9e-125|450|mmu:99377|sal-like protein GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0014020;GO:0006366//transcription from RNA polymerase II promoter;GO:0035108//limb morphogenesis;GO:0001832//blastocyst growth;GO:0003231//cardiac ventricle development;GO:0014020;GO:0006366//transcription from RNA polymerase II promoter;GO:0035108//limb morphogenesis;GO:0001832//blastocyst growth;GO:0003231//cardiac ventricle development;GO:0014020;GO:0006366//transcription from RNA polymerase II promoter;GO:0035108//limb morphogenesis;GO:0001832//blastocyst growth;GO:0003231//cardiac ventricle development gi|117553631|ref|NP_780512.2|/0/sal-like protein 4 isoform a [Mus musculus] 17135 2825 28.75 31.34 0.124443224 Up 0.287995036 Mafk "v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)" K09037|1|6e-69|265|hgl:101707776|transcription factor MAFF/G/K GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0048731//system development;GO:0006351//transcription, DNA-templated" gi|512956137|ref|XP_004840408.1|/4.78301e-68/PREDICTED: transcription factor MafK isoform X1 [Heterocephalus glaber] 56208 2031 31.23 28.64 -0.124901077 Down 0.287995036 Becn1 "beclin 1, autophagy related" K08334|1|0.0|839|mmu:56208|beclin 1 GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0005488//binding GO:0010508//positive regulation of autophagy;GO:0008283//cell proliferation;GO:0007033//vacuole organization;GO:0010044//response to aluminum ion;GO:0006518//peptide metabolic process;GO:0002252;GO:0014070//response to organic cyclic compound;GO:0009607//response to biotic stimulus;GO:0008219//cell death;GO:0006950//response to stress;GO:0070849//response to epidermal growth factor;GO:0030182//neuron differentiation gi|27764875|ref|NP_062530.2|/0/beclin-1 [Mus musculus] 11419 3800 0.963333333 1.316666667 0.450783161 Up 0.287995036 Asic1 acid-sensing (proton-gated) ion channel 1 K04829|1|0.0|1088|cge:100751471|acid-sensing ion channel 1 GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0016021//integral component of membrane;GO:0030425//dendrite GO:0005488//binding;GO:0005272//sodium channel activity;GO:0005488//binding;GO:0005272//sodium channel activity GO:0006814//sodium ion transport;GO:0007600//sensory perception;GO:0007612//learning;GO:0042221//response to chemical;GO:0007269//neurotransmitter secretion;GO:0006873//cellular ion homeostasis;GO:0006816//calcium ion transport;GO:0006814//sodium ion transport;GO:0007600//sensory perception;GO:0007612//learning;GO:0042221//response to chemical;GO:0007269//neurotransmitter secretion;GO:0006873//cellular ion homeostasis;GO:0006816//calcium ion transport gi|45433493|ref|NP_033727.1|/0/acid-sensing ion channel 1 isoform 2 [Mus musculus] 212514 4342 1.62 1.236666667 -0.389537127 Down 0.287957426 Spice1 spindle and centriole associated protein 1 K16490|1|0.0|1438|mmu:212514|spindle and centriole-associated protein 1 GO:0005813//centrosome - GO:0007059//chromosome segregation;GO:0000087//mitotic M phase;GO:0007052//mitotic spindle organization;GO:0007099//centriole replication gi|257196267|ref|NP_653133.3|/0/spindle and centriole-associated protein 1 [Mus musculus] 11987 7103.11 13.13333333 14.45 0.137836364 Up 0.287882207 Slc7a1 "solute carrier family 7 (cationic amino acid transporter, y+ system), member 1" "K13863|1|0.0|1129|mmu:11987|solute carrier family 7 (cationic amino acid transporter), member 1" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0015171//amino acid transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity GO:0006865//amino acid transport;GO:0009966//regulation of signal transduction;GO:0006812//cation transport;GO:0006865//amino acid transport;GO:0009966//regulation of signal transduction;GO:0006812//cation transport "gi|148673899|gb|EDL05846.1|/0/solute carrier family 7 (cationic amino acid transporter, y+ system), member 1, partial [Mus musculus]" 215280 4482.06 5.963333333 5.233333333 -0.188388828 Down 0.287844597 Wipf1 "WAS/WASL interacting protein family, member 1" K19475|1|2e-102|377|mmu:215280|WAS/WASL-interacting protein GO:0005856//cytoskeleton;GO:0005856//cytoskeleton;GO:0005856//cytoskeleton - GO:0044763;GO:0044763;GO:0044763 gi|23346579|ref|NP_694778.1|/1.44949e-101/WAS/WASL-interacting protein family member 1 [Mus musculus] 14756 4659 4.313333333 3.713333333 -0.216088385 Down 0.287806988 Gpld1 glycosylphosphatidylinositol specific phospholipase D1 K01127|1|0.0|1616|mmu:14756|glycosylphosphatidylinositol phospholipase D [EC:3.1.4.50] GO:0043227//membrane-bounded organelle;GO:0005737//cytoplasm;GO:0034358//plasma lipoprotein particle;GO:0031012//extracellular matrix GO:0004630//phospholipase D activity;GO:0016247//channel regulator activity GO:0032024//positive regulation of insulin secretion;GO:0006006//glucose metabolic process;GO:0032868//response to insulin;GO:0006915//apoptotic process;GO:0010982;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0002429//immune response-activating cell surface receptor signaling pathway;GO:0006509//membrane protein ectodomain proteolysis;GO:0009268//response to pH;GO:0051592//response to calcium ion;GO:0010040//response to iron(II) ion;GO:0036315//cellular response to sterol;GO:0010692;GO:0006505//GPI anchor metabolic process;GO:0010594//regulation of endothelial cell migration;GO:0030154//cell differentiation;GO:0019835//cytolysis;GO:0008283//cell proliferation;GO:0010896//regulation of triglyceride catabolic process;GO:0010866//regulation of triglyceride biosynthetic process;GO:0009746;GO:0042493//response to drug;GO:0002040//sprouting angiogenesis;GO:0034014//response to triglyceride gi|111378397|ref|NP_032182.2|/0/phosphatidylinositol-glycan-specific phospholipase D precursor [Mus musculus] 76306 2837 3.62 4.22 0.221253302 Up 0.287806988 Slc18b1 "solute carrier family 18, subfamily B, member 1" "K08155|1|1e-17|95.1|acs:100555672|MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2" - - - "gi|148672822|gb|EDL04769.1|/0/mCG114622, partial [Mus musculus]" 79464 2877.71 19.16 17.45 -0.134870525 Down 0.287788183 Lias lipoic acid synthetase K03644|1|0.0|763|mmu:79464|lipoyl synthase [EC:2.8.1.8] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0016783//sulfurtransferase activity;GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding;GO:0016783//sulfurtransferase activity;GO:0051536//iron-sulfur cluster binding GO:0006952//defense response;GO:0014020;GO:0006633//fatty acid biosynthetic process;GO:0018065//protein-cofactor linkage;GO:0002237//response to molecule of bacterial origin;GO:0006952//defense response;GO:0014020;GO:0006633//fatty acid biosynthetic process;GO:0018065//protein-cofactor linkage;GO:0002237//response to molecule of bacterial origin "gi|148705793|gb|EDL37740.1|/0/lipoic acid synthetase, isoform CRA_b, partial [Mus musculus]" 319216 726 0.713333333 0.43 -0.730239731 Down 0.287722366 4932441J04Rik RIKEN cDNA 4932441J04 gene - - - - - 75627 2125 1.82 2.26 0.312384322 Up 0.287722366 Snapc1 "small nuclear RNA activating complex, polypeptide 1" K15208|1|0.0|664|mmu:75627|snRNA-activating protein complex subunit 1 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" "gi|148704550|gb|EDL36497.1|/0/small nuclear RNA activating complex, polypeptide 1 [Mus musculus]" 74467 3269.37 2.263333333 1.823333333 -0.311870741 Down 0.287722366 Pus10 pseudouridylate synthase 10 K07583|1|0.0|1027|mmu:74467|tRNA pseudouridine synthase 10 [EC:5.4.99.-] - GO:0016866//intramolecular transferase activity;GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0003676//nucleic acid binding GO:0006399//tRNA metabolic process;GO:0006399//tRNA metabolic process;GO:0006399//tRNA metabolic process "gi|148675948|gb|EDL07895.1|/0/RIKEN cDNA 4933435A13, isoform CRA_c, partial [Mus musculus]" 231287 6036.33 1.8 2.236666667 0.313353359 Up 0.287722366 Atp10d "ATPase, class V, type 10D" K01530|1|0.0|2875|mmu:231287|phospholipid-translocating ATPase [EC:3.6.3.1] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0032550;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0032550;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0008324//cation transmembrane transporter activity GO:0044763;GO:0006811//ion transport;GO:0015914//phospholipid transport;GO:0044763;GO:0006811//ion transport;GO:0015914//phospholipid transport gi|294979203|ref|NP_700438.3|/0/probable phospholipid-transporting ATPase VD precursor [Mus musculus] 268291 2873 4.02 4.663333333 0.214166055 Up 0.287703562 Rnf217 ring finger protein 217 K11977|1|0.0|796|mmu:268291|E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.27] - - - gi|226437653|ref|NP_001139821.1|/0/probable E3 ubiquitin-protein ligase RNF217 [Mus musculus] 67905 1844 4.623333333 5.306666667 0.198872548 Up 0.287665952 Ppm1m protein phosphatase 1M K17507|1|0.0|825|mmu:67905|protein phosphatase 1M [EC:3.1.3.16] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0004722//protein serine/threonine phosphatase activity GO:0006464//cellular protein modification process gi|171460924|ref|NP_945149.2|/0/protein phosphatase 1M isoform 2 [Mus musculus] 192192 2347 5.286666667 4.606666667 -0.198635155 Down 0.287665952 Shkbp1 Sh3kbp1 binding protein 1 "K06115|1|1e-97|360|asn:102373253|spectrin beta;K03849|2|3e-11|73.2|cmk:103177229|alpha-1,3-glucosyltransferase [EC:2.4.1.265];K20131|3|1e-10|71.2|cmy:102940364|Rab5 GDP/GTP exchange factor" - - GO:0051259//protein oligomerization gi|109659851|ref|NP_619617.2|/0/SH3KBP1-binding protein 1 [Mus musculus] 12323 4015.56 4.51 5.193333333 0.203533394 Up 0.287665952 Camk2b "calcium/calmodulin-dependent protein kinase II, beta" K04515|1|0.0|1066|rno:24245|calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] GO:0030139//endocytic vesicle;GO:0031981//nuclear lumen;GO:0005819//spindle;GO:0005789//endoplasmic reticulum membrane;GO:0005819//spindle;GO:0005783//endoplasmic reticulum;GO:0030139//endocytic vesicle;GO:0031981//nuclear lumen;GO:0005819//spindle;GO:0005789//endoplasmic reticulum membrane GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0032550;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0008092//cytoskeletal protein binding "GO:0043501//skeletal muscle adaptation;GO:0050773//regulation of dendrite development;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0051094//positive regulation of developmental process;GO:0009967//positive regulation of signal transduction;GO:0031346//positive regulation of cell projection organization;GO:0019221//cytokine-mediated signaling pathway;GO:0007271//synaptic transmission, cholinergic;GO:0044772//mitotic cell cycle phase transition;GO:0050807//regulation of synapse organization;GO:0007343//egg activation;GO:0010038//response to metal ion;GO:0050905//neuromuscular process;GO:0006816//calcium ion transport;GO:0048168//regulation of neuronal synaptic plasticity;GO:0006468//protein phosphorylation;GO:0007343//egg activation;GO:0051094//positive regulation of developmental process;GO:0048168//regulation of neuronal synaptic plasticity;GO:0031346//positive regulation of cell projection organization;GO:0010975//regulation of neuron projection development;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0006468//protein phosphorylation;GO:0009967//positive regulation of signal transduction;GO:0010038//response to metal ion;GO:0070838//divalent metal ion transport;GO:0007271//synaptic transmission, cholinergic;GO:0050905//neuromuscular process;GO:0043501//skeletal muscle adaptation;GO:0050773//regulation of dendrite development;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0051094//positive regulation of developmental process;GO:0009967//positive regulation of signal transduction;GO:0031346//positive regulation of cell projection organization;GO:0019221//cytokine-mediated signaling pathway;GO:0007271//synaptic transmission, cholinergic;GO:0044772//mitotic cell cycle phase transition;GO:0050807//regulation of synapse organization;GO:0007343//egg activation;GO:0010038//response to metal ion;GO:0050905//neuromuscular process;GO:0006816//calcium ion transport;GO:0048168//regulation of neuronal synaptic plasticity;GO:0006468//protein phosphorylation" gi|291291008|ref|NP_001167524.1|/0/calcium/calmodulin-dependent protein kinase type II subunit beta isoform 1 [Mus musculus] 320299 2284 3.01 2.513333333 -0.260161464 Down 0.287665952 Iqcb1 IQ calmodulin-binding motif containing 1 K16774|1|0.0|1099|mmu:320299|IQ calmodulin-binding motif-containing protein 1 - - - "gi|148665529|gb|EDK97945.1|/0/IQ calmodulin-binding motif containing 1, isoform CRA_f, partial [Mus musculus]" 665389 615 0.706666667 1.023333333 0.534174391 Up 0.287647147 Gm7616 predicted gene 7616 - - - - - 16579 3988.44 8 7.13 -0.166097923 Down 0.287637745 Kifap3 kinesin-associated protein 3 - GO:0005815//microtubule organizing center;GO:0000228//nuclear chromosome;GO:0044444//cytoplasmic part;GO:0005871//kinesin complex;GO:0005819//spindle;GO:0005815//microtubule organizing center;GO:0000228//nuclear chromosome;GO:0044444//cytoplasmic part;GO:0005871//kinesin complex;GO:0005819//spindle GO:0008092//cytoskeletal protein binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008092//cytoskeletal protein binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0007265//Ras protein signal transduction;GO:0002478;GO:0019222//regulation of metabolic process;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0047496//vesicle transport along microtubule;GO:0033036;GO:0007599//hemostasis;GO:0065003;GO:0008283//cell proliferation;GO:0007265//Ras protein signal transduction;GO:0002478;GO:0019222//regulation of metabolic process;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0047496//vesicle transport along microtubule;GO:0033036;GO:0007599//hemostasis;GO:0065003;GO:0008283//cell proliferation gi|74228967|dbj|BAE21952.1|/0/unnamed protein product [Mus musculus] 12729 3395 6.823333333 7.696666667 0.173757071 Up 0.287637745 Clns1a "chloride channel, nucleotide-sensitive, 1A" "K05019|1|5e-114|415|mmu:12729|chloride channel, nucleotide-sensitive, 1A" GO:0044444//cytoplasmic part - GO:0019725//cellular homeostasis;GO:0015698//inorganic anion transport gi|19263324|ref|NP_076160.1|/4.61995e-113/methylosome subunit pICln [Mus musculus] 108154 6792 0.173333333 0.396666667 1.194378045 Up 0.28761894 Adamts6 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6" K08621|1|0.0|593|mmu:108154|a disintegrin and metalloproteinase with thrombospondin motifs 6 [EC:3.4.24.-] - - - - 18286 3882.21 9.446666667 8.463333333 -0.158579363 Down 0.287524916 Odf2 outer dense fiber of sperm tails 2 K16479|1|0.0|1261|ngi:103742854|outer dense fiber protein 2 GO:0005813//centrosome;GO:0044444//cytoplasmic part;GO:0005819//spindle;GO:0044447;GO:0044447;GO:0005813//centrosome GO:0005488//binding;GO:0005198//structural molecule activity GO:0044772//mitotic cell cycle phase transition;GO:0048232//male gamete generation;GO:0007281//germ cell development;GO:0007281//germ cell development gi|295054183|ref|NP_001171130.1|/0/outer dense fiber protein 2 isoform d [Mus musculus] 213438 2997 0.44 0.723333333 0.717157113 Up 0.287477904 A630033H20Rik RIKEN cDNA A630033H20 gene "K04274|1|0.0|722|mmu:213438|purinergic receptor P2Y, G protein-coupled, 10" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0001608;GO:0001608;GO:0001608 GO:0035588;GO:0035588;GO:0035588 gi|30425170|ref|NP_780651.1|/0/purinergic receptor P2Y G-protein coupled 10-like [Mus musculus] 77891 988 80.00666667 86.36666667 0.11035439 Up 0.287383881 Ube2s ubiquitin-conjugating enzyme E2S K10583|1|4e-110|400|pale:102886584|ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23] GO:0000152//nuclear ubiquitin ligase complex GO:0032550;GO:0019787//ubiquitin-like protein transferase activity GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010993//regulation of ubiquitin homeostasis;GO:0000209//protein polyubiquitination;GO:0000087//mitotic M phase;GO:0051443//positive regulation of ubiquitin-protein transferase activity gi|759175884|ref|XP_011377562.1|/1.04141e-109/PREDICTED: ubiquitin-conjugating enzyme E2 S [Pteropus vampyrus] 245174 6920 1.626666667 2.05 0.333705263 Up 0.287233442 Zfp937 zinc finger protein 937 K09228|1|0.0|1102|mmu:245174|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|215490125|ref|NP_001135883.1|/0/zinc finger protein family member [Mus musculus] 213753 3323 12.46333333 13.76666667 0.14348931 Up 0.287233442 Zfp598 zinc finger protein 598 K14859|1|4e-27|126|smm:Smp_173890|ribosome biogenesis protein SSF1/2 - GO:0046872//metal ion binding - gi|34147169|ref|NP_898972.1|/0/zinc finger protein 598 [Mus musculus] 68732 5158 2.033333333 1.613333333 -0.333802195 Down 0.287233442 Lrrc16a leucine rich repeat containing 16A K20493|1|0.0|2446|mmu:68732|leucine-rich repeat-containing protein 16 - - - gi|154146185|ref|NP_081101.3|/0/leucine-rich repeat-containing protein 16A isoform 1 [Mus musculus] 68801 2802 13.76 12.46 -0.143176402 Down 0.287233442 Elovl5 "ELOVL family member 5, elongation of long chain fatty acids (yeast)" K10244|1|2e-173|612|mmu:68801|elongation of very long chain fatty acids protein 5 [EC:2.3.1.199] GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane GO:0004312//fatty acid synthase activity "GO:0019368//fatty acid elongation, unsaturated fatty acid;GO:0000038//very long-chain fatty acid metabolic process" gi|31981653|ref|NP_599016.2|/2.06211e-172/elongation of very long chain fatty acids protein 5 [Mus musculus] 66078 1518.15 29.84666667 32.34333333 0.115898554 Up 0.287073602 Tsen34 tRNA splicing endonuclease subunit 34 K15323|1|2e-145|518|mmu:66078|tRNA-splicing endonuclease subunit Sen34 [EC:3.1.27.9] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0004518//nuclease activity;GO:0097159//organic cyclic compound binding;GO:0004518//nuclease activity;GO:0097159//organic cyclic compound binding;GO:0004518//nuclease activity;GO:0097159//organic cyclic compound binding "GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation" "gi|148699249|gb|EDL31196.1|/5.78964e-151/mCG18479, isoform CRA_c, partial [Mus musculus]" 16205 1499 6.766666667 5.98 -0.178299837 Down 0.287045395 Gimap1 "GTPase, IMAP family member 1" - GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0032550;GO:0032550 GO:0030098//lymphocyte differentiation;GO:0030098//lymphocyte differentiation "gi|148666152|gb|EDK98568.1|/0/GTPase, IMAP family member 1, isoform CRA_a, partial [Mus musculus]" 24071 10417 6.683333333 5.896666667 -0.180668189 Down 0.287045395 Synj2bp synaptojanin 2 binding protein K20057|1|4e-11|70.5|mmu:24071|synaptojanin-2-binding protein GO:0031306//intrinsic component of mitochondrial outer membrane GO:0070697//activin receptor binding GO:0007265//Ras protein signal transduction;GO:0048311//mitochondrion distribution;GO:0048522;GO:0006897//endocytosis;GO:0032924//activin receptor signaling pathway;GO:0006886//intracellular protein transport "gi|148670762|gb|EDL02709.1|/1.53824e-68/mCG7931, isoform CRA_f, partial [Mus musculus]" 27056 1796.21 6.696666667 7.553333333 0.173670297 Up 0.286979578 Irf5 interferon regulatory factor 5 K09446|1|0.0|933|mmu:27056|interferon regulatory factor 5 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0001067;GO:0001071//nucleic acid binding transcription factor activity;GO:0001067 GO:0006952//defense response;GO:0006915//apoptotic process;GO:0002237//response to molecule of bacterial origin;GO:0002252;GO:1901652//response to peptide;GO:0006366//transcription from RNA polymerase II promoter;GO:0006952//defense response;GO:0006915//apoptotic process;GO:0002237//response to molecule of bacterial origin;GO:0002252;GO:1901652//response to peptide;GO:0006366//transcription from RNA polymerase II promoter gi|568939640|ref|XP_006505158.1|/0/PREDICTED: interferon regulatory factor 5 isoform X2 [Mus musculus] 28126 1734 7.03 7.893333333 0.167109986 Up 0.286979578 Nop16 NOP16 nucleolar protein "K03847|1|8e-09|64.7|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" GO:0031981//nuclear lumen - - gi|30519925|ref|NP_848720.1|/2.52903e-87/nucleolar protein 16 [Mus musculus] 13144 1728 17.36666667 19.04 0.132712607 Up 0.286951371 Dapk3 death-associated protein kinase 3 K08803|1|6e-177|623|rno:64391|death-associated protein kinase [EC:2.7.11.1] GO:0044427;GO:0015630//microtubule cytoskeleton;GO:0016604//nuclear body;GO:0044427;GO:0015630//microtubule cytoskeleton;GO:0016604//nuclear body;GO:0044427;GO:0015630//microtubule cytoskeleton;GO:0016604//nuclear body GO:0030275//LRR domain binding;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0042802//identical protein binding;GO:0030275//LRR domain binding;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0042802//identical protein binding;GO:0030275//LRR domain binding;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0042802//identical protein binding "GO:0006351//transcription, DNA-templated;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0006412//translation;GO:0006468//protein phosphorylation;GO:0012502//induction of programmed cell death;GO:0030154//cell differentiation;GO:0034341//response to interferon-gamma;GO:0006325//chromatin organization;GO:0030177//positive regulation of Wnt signaling pathway;GO:0035556//intracellular signal transduction;GO:0006351//transcription, DNA-templated;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0006412//translation;GO:0006468//protein phosphorylation;GO:0012502//induction of programmed cell death;GO:0030154//cell differentiation;GO:0034341//response to interferon-gamma;GO:0006325//chromatin organization;GO:0030177//positive regulation of Wnt signaling pathway;GO:0035556//intracellular signal transduction;GO:0006351//transcription, DNA-templated;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0006412//translation;GO:0006468//protein phosphorylation;GO:0012502//induction of programmed cell death;GO:0030154//cell differentiation;GO:0034341//response to interferon-gamma;GO:0006325//chromatin organization;GO:0030177//positive regulation of Wnt signaling pathway;GO:0035556//intracellular signal transduction" gi|410812207|ref|NP_001177403.2|/0/death-associated protein kinase 3 isoform a [Mus musculus] 74995 755 0.14 0.01 -3.807354922 Down 0.286941968 4930502E09Rik RIKEN cDNA 4930502E09 gene - - - - - 100504162 959 0.01 0.143333333 3.841302254 Up 0.286941968 Prss51 "protease, serine 51" K01324|1|3e-21|104|oas:101116376|plasma kallikrein [EC:3.4.21.34] - - - "gi|568986207|ref|XP_006518369.1|/1.91041e-129/PREDICTED: protease, serine, 51 isoform X2 [Mus musculus]" 58251 1993 0.01 0.14 3.807354922 Up 0.286941968 BC100451 cDNA sequence BC100451 - GO:0005929//cilium - - gi|568975078|ref|XP_006533922.1|/0/PREDICTED: protein DDC8 isoform X2 [Mus musculus] 100041014 756 0.01 0.14 3.807354922 Up 0.286941968 Gm20857 Sycp3 like Y-linked pseudogene K19528|1|1e-25|109|lve:103085291|synaptonemal complex protein 3 - - - - 72648 641 0.01 0.14 3.807354922 Up 0.286941968 Smc2os "structural maintenance of chromosomes 2, opposite strand" - - - - "gi|148670353|gb|EDL02300.1|/2.52631e-33/mCG1041367, partial [Mus musculus]" 69318 676 0.01 0.14 3.807354922 Up 0.286941968 1700007K09Rik RIKEN cDNA 1700007K09 gene - - - - gi|755523081|ref|XP_006508244.2|/1.08666e-56/PREDICTED: protein FAM24A-like isoform X1 [Mus musculus] 545651 1462 0.01 0.143333333 3.841302254 Up 0.286941968 Gm13278 predicted gene 13278 K05414|1|7e-38|160|cge:100763520|interferon alpha GO:0044421 GO:0005102//receptor binding GO:0007166//cell surface receptor signaling pathway;GO:0030098//lymphocyte differentiation;GO:0002252;GO:0007049//cell cycle;GO:0012501//programmed cell death gi|149588682|ref|NP_001092311.1|/1.88304e-101/interferon zeta-like precursor [Mus musculus] 100039913 761 0.01 0.14 3.807354922 Up 0.286941968 Rhox2b reproductive homeobox 2B K09323|1|5e-06|53.5|umr:103675013|homeobox protein aristaless-like 3;K09452|3|5e-06|53.5|rro:104654158|homeobox protein aristaless-related GO:0043231//intracellular membrane-bounded organelle - - gi|150010650|ref|NP_001092786.1|/2.92591e-86/reproductive homeobox 2B [Mus musculus] 100009600 1010 0.01 0.14 3.807354922 Up 0.286941968 Zglp1 "zinc finger, GATA-like protein 1" K09183|1|1e-06|56.2|dan:Dana_GF11891|GATA-binding protein 4 - - - - 238331 792 0.14 0.01 -3.807354922 Down 0.286941968 Zdhhc22 "zinc finger, DHHC-type containing 22" K18932|1|6e-144|511|mmu:238331|palmitoyltransferase [EC:2.3.1.225] GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0016740//transferase activity GO:0006497//protein lipidation;GO:0007009//plasma membrane organization gi|124301180|ref|NP_001074412.1|/4.81474e-143/palmitoyltransferase ZDHHC22 [Mus musculus] 100861851 729 0.01 0.143333333 3.841302254 Up 0.286941968 Gm21269 "predicted gene, 21269" - - - - - 14293 1332 0.01 0.14 3.807354922 Up 0.286941968 Fpr1 formyl peptide receptor 1 K04172|1|0.0|728|mmu:14293|formyl peptide receptor 1 GO:0031224//intrinsic component of membrane GO:0008528//G-protein coupled peptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0042221//response to chemical;GO:0006801//superoxide metabolic process gi|7305065|ref|NP_038549.1|/0/fMet-Leu-Phe receptor [Mus musculus] 140806 1064 0.01 0.143333333 3.841302254 Up 0.286941968 Il25 interleukin 25 K05493|1|2e-100|367|mmu:140806|interleukin 17E - GO:0005102//receptor binding GO:0006952//defense response;GO:0051707//response to other organism;GO:0030851//granulocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter gi|18141561|ref|NP_542767.1|/1.87534e-99/interleukin-25 [Mus musculus] 67531 408 0.143333333 0.01 -3.841302254 Down 0.286941968 5730408K05Rik RIKEN cDNA 5730408K05 gene - - - - gi|625213889|ref|XP_007647542.1|/5.70415e-06/PREDICTED: uncharacterized protein LOC100755591 [Cricetulus griseus] 66537 734 78.94666667 85.06666667 0.10771557 Up 0.286932566 Pomp proteasome maturation protein K11599|1|2e-64|247|mmu:66537|proteasome maturation protein GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0031981//nuclear lumen - GO:0043623//cellular protein complex assembly "gi|148673893|gb|EDL05840.1|/8.13908e-75/mCG145041, isoform CRA_a, partial [Mus musculus]" 15901 934 80.64666667 74.53666667 -0.113664602 Down 0.286932566 Id1 inhibitor of DNA binding 1 K04680|1|3e-70|267|mmu:15901|DNA-binding protein inhibitor ID1 GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity GO:0001525//angiogenesis;GO:0044259//multicellular organismal macromolecule metabolic process;GO:0001649//osteoblast differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0012501//programmed cell death;GO:0001885//endothelial cell development;GO:0009636//response to toxic substance;GO:0051100//negative regulation of binding;GO:0000165//MAPK cascade;GO:0009887//organ morphogenesis "gi|194091|gb|AAA37879.1|/2.35993e-76/helix-loop-helix protein (Id), partial [Mus musculus]" 74325 1576 76.25666667 82.37 0.111255519 Up 0.286932566 Cltb "clathrin, light polypeptide (Lcb)" K04645|1|5e-90|334|mmu:74325|clathrin light chain B GO:0012510//trans-Golgi network transport vesicle membrane;GO:0030118//clathrin coat;GO:0005905//clathrin-coated pit GO:0005215//transporter activity;GO:0033218//amide binding GO:0006901//vesicle coating;GO:0001505//regulation of neurotransmitter levels;GO:0015031//protein transport gi|74195579|dbj|BAE39600.1|/4.06135e-89/unnamed protein product [Mus musculus] 230597 2170 10.81333333 9.713333333 -0.154772942 Down 0.286923164 Zfyve9 "zinc finger, FYVE domain containing 9" "K04679|1|0.0|1370|mmu:230597|MAD, mothers against decapentaplegic interacting protein" GO:0005769//early endosome GO:0043169//cation binding;GO:0035091//phosphatidylinositol binding;GO:0005515//protein binding GO:0006606//protein import into nucleus;GO:0007179//transforming growth factor beta receptor signaling pathway gi|119508810|ref|NP_899123.2|/0/zinc finger FYVE domain-containing protein 9 [Mus musculus] 259097 2923 1.423333333 1.066666667 -0.416164165 Down 0.286894957 Olfr558 olfactory receptor 558 K04257|1|2e-168|595|mmu:259097|olfactory receptor GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007608//sensory perception of smell gi|22128779|ref|NP_667304.1|/1.60957e-167/olfactory receptor 558 [Mus musculus] 235574 4728.92 9.04 8.073333333 -0.163158313 Down 0.286885554 Atp2c1 "ATPase, Ca++-sequestering" K01537|1|0.0|1292|mmu:235574|Ca2+-transporting ATPase [EC:3.6.3.8] - - - - 20230 6337 2.723333333 2.25 -0.275448576 Down 0.286866749 Satb1 special AT-rich sequence binding protein 1 K19774|1|8e-15|86.7|obi:106881402|homeobox domain-containing protein GO:0034399//nuclear periphery;GO:0016604//nuclear body;GO:0000790//nuclear chromatin;GO:0034399//nuclear periphery;GO:0016604//nuclear body;GO:0000790//nuclear chromatin;GO:0034399//nuclear periphery;GO:0016604//nuclear body;GO:0000790//nuclear chromatin;GO:0034399//nuclear periphery;GO:0016604//nuclear body;GO:0000790//nuclear chromatin GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0009888//tissue development;GO:0009605//response to external stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0035710//CD4-positive, alpha-beta T cell activation;GO:0006479//protein methylation;GO:0016568//chromatin modification;GO:0036037//CD8-positive, alpha-beta T cell activation;GO:0042098//T cell proliferation;GO:0009888//tissue development;GO:0009605//response to external stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0035710//CD4-positive, alpha-beta T cell activation;GO:0006479//protein methylation;GO:0016568//chromatin modification;GO:0036037//CD8-positive, alpha-beta T cell activation;GO:0042098//T cell proliferation;GO:0009888//tissue development;GO:0009605//response to external stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0035710//CD4-positive, alpha-beta T cell activation;GO:0006479//protein methylation;GO:0016568//chromatin modification;GO:0036037//CD8-positive, alpha-beta T cell activation;GO:0042098//T cell proliferation;GO:0009888//tissue development;GO:0009605//response to external stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0035710//CD4-positive, alpha-beta T cell activation;GO:0006479//protein methylation;GO:0016568//chromatin modification;GO:0036037//CD8-positive, alpha-beta T cell activation;GO:0042098//T cell proliferation" gi|254826759|ref|NP_001157102.1|/0/DNA-binding protein SATB1 [Mus musculus] 211006 1925 0.946666667 0.64 -0.564784619 Down 0.286866749 Sepsecs Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase K03341|1|0.0|1004|mmu:211006|O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase [EC:2.9.1.2] GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding;GO:0043168//anion binding;GO:0016740//transferase activity GO:0006451//translational readthrough;GO:0006399//tRNA metabolic process gi|27369676|ref|NP_766078.1|/0/O-phosphoseryl-tRNA(Sec) selenium transferase [Mus musculus] 17955 2315.09 81.71 75.66333333 -0.110918317 Down 0.286838542 Nap1l4 nucleosome assembly protein 1-like 4 K11282|1|0.0|639|ngi:103738973|nucleosome assembly protein 1-like 4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0034728//nucleosome organization;GO:0034728//nucleosome organization;GO:0034728//nucleosome organization gi|26354943|dbj|BAC41098.1|/0/unnamed protein product [Mus musculus] 18432 4215 30.89666667 28.42333333 -0.120375443 Down 0.286810335 Mybbp1a MYB binding protein (P160) 1a K02331|1|0.0|2267|mmu:18432|DNA polymerase phi [EC:2.7.7.7] GO:0031981//nuclear lumen;GO:0031074//nucleocytoplasmic shuttling complex GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0034061//DNA polymerase activity "GO:0006351//transcription, DNA-templated;GO:0072331//signal transduction by p53 class mediator;GO:0022900//electron transport chain;GO:0007050//cell cycle arrest;GO:0051169//nuclear transport;GO:0009267//cellular response to starvation" gi|31982724|ref|NP_058056.2|/0/myb-binding protein 1A [Mus musculus] 68810 2580 81.44666667 75.44666667 -0.110398493 Down 0.286753921 Nexn nexilin K00907|1|3e-15|86.7|cmk:103176418|myosin-light-chain kinase [EC:2.7.11.18] GO:0005912//adherens junction;GO:0031674//I band GO:0003779//actin binding;GO:0005198//structural molecule activity GO:0016477//cell migration;GO:0007010//cytoskeleton organization "gi|148679982|gb|EDL11929.1|/0/nexilin, isoform CRA_a, partial [Mus musculus]" 12494 3013 5.816666667 5.096666667 -0.19063863 Down 0.286697506 Cd38 CD38 antigen K01242|1|1e-159|566|mmu:12494|ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20] - - - - 24083 4159 5.11 5.83 0.190172592 Up 0.286697506 Natd1 N-acetyltransferase domain containing 1 K06975|1|2e-58|230|rno:363614|uncharacterized protein - - - gi|13384646|ref|NP_079570.1|/2.02011e-57/protein NATD1 [Mus musculus] 70556 1877 27.38333333 29.83 0.123465903 Up 0.286612885 Slc25a33 "solute carrier family 25, member 33" "K15116|1|2e-177|625|mmu:70556|solute carrier family 25, member 33/36" GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0051234//establishment of localization gi|117647275|ref|NP_081736.2|/1.45349e-176/solute carrier family 25 member 33 [Mus musculus] 104836 4004 3.56 3.023333333 -0.235737191 Down 0.286612885 Cbll1 Casitas B-lineage lymphoma-like 1 K15685|1|0.0|660|mmu:104836|E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27] GO:0043234//protein complex;GO:0044464 GO:0005488//binding;GO:0005488//binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0016477//cell migration;GO:0032446//protein modification by small protein conjugation;GO:0007155//cell adhesion;GO:0006897//endocytosis;GO:0016477//cell migration;GO:0032446//protein modification by small protein conjugation;GO:0007155//cell adhesion;GO:0006897//endocytosis;GO:0016477//cell migration;GO:0032446//protein modification by small protein conjugation;GO:0007155//cell adhesion;GO:0006897//endocytosis "gi|148704967|gb|EDL36914.1|/0/Casitas B-lineage lymphoma-like 1, isoform CRA_b, partial [Mus musculus]" 66816 3408 0.97 1.32 0.444481277 Up 0.28659408 Thap2 "THAP domain containing, apoptosis associated protein 2" "K09228|1|1e-10|72.0|gja:107120690|KRAB domain-containing zinc finger protein;K03847|4|8e-06|43.9|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - GO:0003676//nucleic acid binding;GO:0043169//cation binding - gi|13385250|ref|NP_080056.1|/3.32442e-111/THAP domain-containing protein 2 [Mus musculus] 67778 1937 12.56333333 13.84666667 0.140319421 Up 0.286509459 Zfp639 zinc finger protein 639 K09228|1|2e-35|153|bfo:BRAFLDRAFT_119785|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding "GO:0006351//transcription, DNA-templated;GO:0032897//negative regulation of viral transcription;GO:0019048//modulation by virus of host morphology or physiology;GO:0016049//cell growth;GO:0043921;GO:0006351//transcription, DNA-templated;GO:0032897//negative regulation of viral transcription;GO:0019048//modulation by virus of host morphology or physiology;GO:0016049//cell growth;GO:0043921" gi|21362299|ref|NP_653102.1|/0/zinc finger protein 639 [Mus musculus] 217449 3209.92 13.53666667 12.25333333 -0.143698261 Down 0.286509459 Trappc12 trafficking protein particle complex 12 K20309|1|0.0|1014|mmu:217449|trafficking protein particle complex subunit 12 - - GO:0006810//transport;GO:0006810//transport;GO:0006810//transport "gi|148705002|gb|EDL36949.1|/0/tetratricopeptide repeat domain 15, isoform CRA_b, partial [Mus musculus]" 228788 2205 13.96 12.68333333 -0.138364989 Down 0.286509459 Ccm2l cerebral cavernous malformation 2-like - - - - gi|755499408|ref|XP_006499388.2|/0/PREDICTED: cerebral cavernous malformations 2 protein-like isoform X1 [Mus musculus] 268481 2735 10.19666667 11.28333333 0.146095727 Up 0.286500056 Krt222 keratin 222 "K10379|1|9e-21|105|dre:494090|phakinin;K07604|2|8e-20|102|lcm:102364302|type I keratin, acidic" GO:0043234//protein complex - - gi|27370460|ref|NP_766534.1|/1.49312e-151/keratin-like protein KRT222 [Mus musculus] 13423 1643 4.473333333 5.14 0.200418094 Up 0.286471849 Dnase2a deoxyribonuclease II alpha K01158|1|0.0|710|mmu:13423|deoxyribonuclease II [EC:3.1.22.1] GO:0000323//lytic vacuole "GO:0016889//endodeoxyribonuclease activity, producing 3'-phosphomonoesters" GO:0012501//programmed cell death;GO:0006259//DNA metabolic process;GO:0030099//myeloid cell differentiation gi|6753654|ref|NP_034192.1|/0/deoxyribonuclease-2-alpha precursor [Mus musculus] 229541 5419 18.93 17.27666667 -0.131849518 Down 0.28643424 Dennd4b DENN/MADD domain containing 4B K20163|1|0.0|2689|mmu:229541|DENN domain-containing protein 4 - - - gi|164565362|ref|NP_958809.3|/0/DENN domain-containing protein 4B [Mus musculus] 621823 1066 0.906666667 0.606666667 -0.579668201 Down 0.28639663 Psme2b "protease (prosome, macropain) activator subunit 2B" K06697|1|5e-122|439|mmu:621823|proteasome activator subunit 2 (PA28 beta) - GO:0061135 GO:0010952//positive regulation of peptidase activity;GO:0019882//antigen processing and presentation gi|20137004|ref|NP_035320.1|/3.90161e-121/proteasome activator complex subunit 2 isoform 1 [Mus musculus] 20517 1994 0.593333333 0.89 0.584962501 Up 0.28639663 Slc22a1 "solute carrier family 22 (organic cation transporter), member 1" "K08198|1|0.0|1085|mmu:20517|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1" GO:0044459;GO:0016021//integral component of membrane GO:0008504//monoamine transmembrane transporter activity;GO:0005515//protein binding;GO:0015101//organic cation transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity GO:0015893//drug transport;GO:0009914//hormone transport;GO:0034220//ion transmembrane transport;GO:0051937;GO:0006812//cation transport gi|31982010|ref|NP_033228.2|/0/solute carrier family 22 member 1 [Mus musculus] 16625 1690 0.59 0.333333333 -0.82374936 Down 0.28639663 Serpina3c "serine (or cysteine) peptidase inhibitor, clade A, member 3C" "K04525|1|0.0|820|mmu:16625|serpin peptidase inhibitor, clade A" - - - gi|755542214|ref|XP_011242304.1|/0/PREDICTED: serine protease inhibitor A3C isoform X2 [Mus musculus] 12337 4351 1.05 0.733333333 -0.517848305 Down 0.286359021 Capn5 calpain 5 K08574|1|0.0|1299|mmu:12337|calpain-5 [EC:3.4.22.-] GO:0044464 GO:0004197//cysteine-type endopeptidase activity GO:0008585//female gonad development;GO:0030154//cell differentiation;GO:0019538//protein metabolic process gi|568949484|ref|XP_006507338.1|/0/PREDICTED: calpain-5 isoform X2 [Mus musculus] 320207 4363 0.736666667 1.056666667 0.520436471 Up 0.286359021 Pik3r5 "phosphoinositide-3-kinase, regulatory subunit 5, p101" "K02649|1|0.0|1641|mmu:320207|phosphoinositide-3-kinase, regulatory subunit" GO:0043234//protein complex;GO:0044424 "GO:0035014//phosphatidylinositol 3-kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0043550//regulation of lipid kinase activity gi|86262161|ref|NP_796294.2|/0/phosphoinositide 3-kinase regulatory subunit 5 [Mus musculus] 21335 2649 1.44 1.84 0.353636955 Up 0.286330813 Tacc3 "transforming, acidic coiled-coil containing protein 3" K14283|1|0.0|1152|mmu:21335|transforming acidic coiled-coil-containing protein 3 GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center GO:0005515//protein binding;GO:0005515//protein binding GO:0050896//response to stimulus;GO:0021846//cell proliferation in forebrain;GO:0048534//hematopoietic or lymphoid organ development;GO:0021543//pallium development;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0007051//spindle organization;GO:0050896//response to stimulus;GO:0021846//cell proliferation in forebrain;GO:0048534//hematopoietic or lymphoid organ development;GO:0021543//pallium development;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0007051//spindle organization "gi|148705482|gb|EDL37429.1|/0/transforming, acidic coiled-coil containing protein 3, isoform CRA_b, partial [Mus musculus]" 16173 866 0.286666667 0.533333333 0.89566334 Up 0.286293204 Il18 interleukin 18 K05482|1|1e-106|388|mmu:16173|interleukin 18 GO:0044459;GO:0044424;GO:0044421 GO:0005126//cytokine receptor binding "GO:0043065//positive regulation of apoptotic process;GO:0010467//gene expression;GO:0034614//cellular response to reactive oxygen species;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032609//interferon-gamma production;GO:0032611//interleukin-1 beta production;GO:0009612//response to mechanical stimulus;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0002176//male germ cell proliferation;GO:0034341//response to interferon-gamma;GO:0019233//sensory perception of pain;GO:0001503//ossification;GO:0032870//cellular response to hormone stimulus;GO:0032616//interleukin-13 production;GO:0042748//circadian sleep/wake cycle, non-REM sleep;GO:0001819//positive regulation of cytokine production;GO:0001974//blood vessel remodeling;GO:0097191//extrinsic apoptotic signaling pathway;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0001866//NK T cell proliferation;GO:0001787//natural killer cell proliferation;GO:0043114//regulation of vascular permeability;GO:0051591//response to cAMP;GO:0007155//cell adhesion;GO:0030323//respiratory tube development;GO:0034612//response to tumor necrosis factor;GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;GO:0032496//response to lipopolysaccharide;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0042102//positive regulation of T cell proliferation" gi|755528372|ref|XP_011240703.1|/1.40039e-141/PREDICTED: interleukin-18 isoform X2 [Mus musculus] 210982 6579 2.846666667 2.366666667 -0.266417045 Down 0.286293204 Gltscr1l GLTSCR1-like K14971|1|4e-16|91.3|phu:Phum_PHUM494000|nuclear receptor coactivator 6;K04494|4|2e-06|59.3|spu:577327|chromodomain helicase DNA binding protein 8 [EC:3.6.4.12];K13908|5|4e-06|57.8|ngi:103751114|mucin-5B - - - gi|755556272|ref|XP_011244648.1|/0/PREDICTED: GLTSCR1-like protein isoform X3 [Mus musculus] 192970 1421 73.76333333 79.48 0.107688021 Up 0.286255594 Dhrs11 dehydrogenase/reductase (SDR family) member 11 K15890|1|4e-55|218|phu:Phum_PHUM184020|NADP+-dependent farnesol dehydrogenase [EC:1.1.1.216] - - - - 69784 1211 1.526666667 1.156666667 -0.400411936 Down 0.286227387 1500009L16Rik RIKEN cDNA 1500009L16 gene K02953|1|4e-16|88.2|umr:103676563|small subunit ribosomal protein S13e - - - gi|537241732|gb|ERE87282.1|/5.30789e-33/putative overexpressed in colon carcinoma 1 protein like protein [Cricetulus griseus] 223770 5137 9.453333333 8.49 -0.155058573 Down 0.28619918 Brd1 bromodomain containing 1 K11349|1|0.0|2110|mmu:223770|bromodomain-containing protein 1 GO:0070775 GO:0005515//protein binding GO:0016573//histone acetylation gi|164698417|ref|NP_001028446.2|/0/bromodomain-containing protein 1 [Mus musculus] 12581 1271 8.326666667 9.283333333 0.156903851 Up 0.28619918 Cdkn2d "cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)" K06623|1|4e-88|327|mmu:12581|cyclin-dependent kinase inhibitor 2D GO:0043231//intracellular membrane-bounded organelle GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0019900//kinase binding GO:0044772//mitotic cell cycle phase transition;GO:0008283//cell proliferation;GO:0016310//phosphorylation;GO:0006915//apoptotic process;GO:0050954//sensory perception of mechanical stimulus;GO:0014070//response to organic cyclic compound;GO:0009416//response to light stimulus;GO:0016049//cell growth;GO:0033993//response to lipid;GO:0006281//DNA repair "gi|159162080|pdb|1AP7|A/2.81832e-87/Chain A, P19-Ink4d From Mouse, Nmr, 20 Structures" 68767 2894 12.58 13.85 0.138754054 Up 0.286170973 Wash1 WAS protein family homolog 1 K18461|1|0.0|693|mmu:68767|WAS protein family homolog 1 GO:0043234//protein complex;GO:0005769//early endosome;GO:0010008//endosome membrane;GO:0043234//protein complex;GO:0005769//early endosome;GO:0010008//endosome membrane GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0016192//vesicle-mediated transport;GO:0044765//single-organism transport;GO:0045010//actin nucleation;GO:0016192//vesicle-mediated transport;GO:0044765//single-organism transport;GO:0045010//actin nucleation gi|74181690|dbj|BAE32561.1|/0/unnamed protein product [Mus musculus] 26919 3597 5.89 6.673333333 0.180139934 Up 0.286114559 Zfp346 zinc finger protein 346 "K10137|1|4e-10|70.1|cmk:103175826|zinc finger, matrin type 3" GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0003723//RNA binding GO:0012501//programmed cell death gi|568983381|ref|XP_006517322.1|/1.41445e-152/PREDICTED: zinc finger protein 346 isoform X1 [Mus musculus] 67197 826 75.28333333 69.71333333 -0.110895896 Down 0.286020535 Zcrb1 zinc finger CCHC-type and RNA binding motif 1 K13154|1|1e-95|351|mmu:67197|U11/U12 small nuclear ribonucleoprotein 31 kDa protein GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding GO:0006396//RNA processing "gi|148672336|gb|EDL04283.1|/1.93106e-97/mCG19744, isoform CRA_b, partial [Mus musculus]" 18975 4596 18.74333333 17.11666667 -0.13097577 Down 0.286020535 Polg "polymerase (DNA directed), gamma" K02332|1|0.0|2394|mmu:18975|DNA polymerase gamma 1 [EC:2.7.7.7] GO:0019866//organelle inner membrane;GO:0005759//mitochondrial matrix GO:0003676//nucleic acid binding;GO:0019899//enzyme binding;GO:0034061//DNA polymerase activity;GO:0004518//nuclease activity GO:0006261//DNA-dependent DNA replication;GO:0044767//single-organism developmental process "gi|148675119|gb|EDL07066.1|/0/polymerase (DNA directed), gamma, isoform CRA_b, partial [Mus musculus]" 12850 944 67.88333333 73.44 0.11350865 Up 0.28600173 Coq7 demethyl-Q 7 K06134|1|1e-88|329|mmu:12850|ubiquinone biosynthesis monooxygenase Coq7 [EC:1.14.13.-] GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0046872//metal ion binding;GO:0003824//catalytic activity GO:0006979//response to oxidative stress;GO:0043009//chordate embryonic development;GO:0010259//multicellular organism aging;GO:0001838//embryonic epithelial tube formation;GO:0006743//ubiquinone metabolic process;GO:0042773//ATP synthesis coupled electron transport;GO:0042221//response to chemical;GO:0007399//nervous system development;GO:0007005//mitochondrion organization "gi|756141038|ref|NP_001291687.1|/1.40772e-179/5-demethoxyubiquinone hydroxylase, mitochondrial isoform 2 [Mus musculus] " 71932 2416 1.633333333 1.256666667 -0.378217226 Down 0.285954718 Ephx3 epoxide hydrolase 3 "K08059|1|2e-32|143|bfo:BRAFLDRAFT_126371|interferon, gamma-inducible protein 30;K08726|2|2e-29|134|bom:102267808|soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]" - - - gi|83716015|ref|NP_001028335.1|/0/epoxide hydrolase 3 [Mus musculus] 14537 4539 0.536666667 0.29 -0.887973382 Down 0.285926511 Gcnt1 "glucosaminyl (N-acetyl) transferase 1, core 2" "K00727|1|0.0|872|mmu:14537|beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase [EC:2.4.1.102]" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0044421 GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity GO:0043434//response to peptide hormone;GO:0001822//kidney development;GO:0009653//anatomical structure morphogenesis;GO:0006493//protein O-linked glycosylation;GO:0043434//response to peptide hormone;GO:0001822//kidney development;GO:0009653//anatomical structure morphogenesis;GO:0006493//protein O-linked glycosylation;GO:0043434//response to peptide hormone;GO:0001822//kidney development;GO:0009653//anatomical structure morphogenesis;GO:0006493//protein O-linked glycosylation "gi|569006401|ref|XP_006526742.1|/0/PREDICTED: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase isoform X1 [Mus musculus]" 29816 4402 10.89333333 9.816666667 -0.150140349 Down 0.285898304 Hip1r huntingtin interacting protein 1 related K20040|1|0.0|1897|mmu:29816|huntingtin-interacting protein 1-related protein GO:0012505//endomembrane system;GO:0043232;GO:0030136//clathrin-coated vesicle GO:0005543//phospholipid binding;GO:0008092//cytoskeletal protein binding GO:0006897//endocytosis gi|37360028|dbj|BAC97992.1|/0/mKIAA0655 protein [Mus musculus] 76261 1870 0.656666667 0.39 -0.7516871 Down 0.285860694 0610040J01Rik RIKEN cDNA 0610040J01 gene - - - - "gi|148705758|gb|EDL37705.1|/0/RIKEN cDNA 0610040J01, isoform CRA_c [Mus musculus]" 258571 3744 2.993333333 2.506666667 -0.255982783 Down 0.285747866 Olfr1033 olfactory receptor 1033 K04257|1|5e-174|614|mmu:258571|olfactory receptor GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007608//sensory perception of smell gi|22129493|ref|NP_666789.1|/4.43182e-173/olfactory receptor 1033 [Mus musculus] 78004 1381 0.18 0.396666667 1.139930261 Up 0.285710256 Prr15 proline rich 15 - - - GO:0032502//developmental process "gi|149033319|gb|EDL88120.1|/2.83026e-68/similar to RIKEN cDNA E130201N16 (predicted), isoform CRA_a [Rattus norvegicus]" 13559 1763 1.883333333 2.326666667 0.304976169 Up 0.285691451 E2f5 E2F transcription factor 5 K04682|1|8e-139|496|mmu:13559|transcription factor E2F4/5 GO:0031981//nuclear lumen;GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0012505//endomembrane system GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0009653//anatomical structure morphogenesis;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0051318 gi|31982405|ref|NP_031918.2|/7.17583e-138/transcription factor E2F5 [Mus musculus] 101471 5374 9.223333333 8.273333333 -0.156819528 Down 0.285588025 Phrf1 PHD and ring finger domains 1 K17586|1|0.0|1565|mmu:101471|PHD and RING finger domain-containing protein 1 - - - gi|568952266|ref|XP_006536210.1|/0/PREDICTED: PHD and RING finger domain-containing protein 1 isoform X10 [Mus musculus] 71769 2753 0.463333333 0.746666667 0.688413849 Up 0.28556922 Bbs10 Bardet-Biedl syndrome 10 (human) K19401|1|0.0|1411|mmu:71769|Bardet-Biedl syndrome 10 protein GO:0044464 GO:0032550 GO:0001894//tissue homeostasis;GO:0043623//cellular protein complex assembly;GO:0019538//protein metabolic process;GO:0007601//visual perception;GO:0042384//cilium assembly gi|254553416|ref|NP_082190.1|/0/Bardet-Biedl syndrome 10 protein homolog [Mus musculus] 237256 4093 0.063333333 0.25 1.980891177 Up 0.285550416 Zc3h12d zinc finger CCCH type containing 12D K18668|1|0.0|1085|mmu:237256|ribonuclease ZC3H12 [EC:3.1.-.-] - - - - 232288 5043 4.94 5.646666667 0.192888427 Up 0.285550416 Frmd4b FERM domain containing 4B K05763|1|6e-35|153|ola:101173478|moesin;K05762|2|6e-34|149|tad:TRIADDRAFT_25177|radixin;K08007|5|1e-33|148|cfr:102523381|villin 2 (ezrin) GO:0031252//cell leading edge;GO:0043232 GO:0005488//binding GO:0030010//establishment of cell polarity gi|37360188|dbj|BAC98072.1|/0/mKIAA1013 protein [Mus musculus] 226976 4711.91 18.45666667 16.84333333 -0.131964342 Down 0.285550416 Kansl3 KAT8 regulatory NSL complex subunit 3 K16719|1|0.0|1403|mmu:226976|regulatory NSL complex subunit 3 GO:0043231//intracellular membrane-bounded organelle - GO:0043967//histone H4 acetylation gi|887239940|ref|NP_001297442.1|/0/KAT8 regulatory NSL complex subunit 3 isoform 1 [Mus musculus] 17993 1534 69.75333333 75.07 0.105974322 Up 0.285541013 Ndufs4 NADH dehydrogenase (ubiquinone) Fe-S protein 4 K03937|1|2e-86|322|mmu:17993|NADH dehydrogenase (ubiquinone) Fe-S protein 4 GO:0005746//mitochondrial respiratory chain;GO:0030964//NADH dehydrogenase complex GO:0050136//NADH dehydrogenase (quinone) activity GO:0007417//central nervous system development;GO:0006468//protein phosphorylation;GO:0046683//response to organophosphorus;GO:0010257//NADH dehydrogenase complex assembly;GO:0015980//energy derivation by oxidation of organic compounds;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0008284//positive regulation of cell proliferation "gi|148686433|gb|EDL18380.1|/1.21562e-90/NADH dehydrogenase (ubiquinone) Fe-S protein 4, partial [Mus musculus]" 140703 1911 1.753333333 1.366666667 -0.35943889 Down 0.285522208 Emid1 EMI domain containing 1 "K13209|1|2e-07|60.1|fab:101814762|RNA-binding protein EWS;K16630|2|5e-07|48.9|ggo:101125599|collagen, type XXII, alpha" GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle - - gi|568969871|ref|XP_006514577.1|/0/PREDICTED: EMI domain-containing protein 1 isoform X1 [Mus musculus] 14287 2265 3.17 3.73 0.23469279 Up 0.285494001 Fpgs folylpolyglutamyl synthetase K01930|1|0.0|1167|mmu:14287|folylpolyglutamate synthase [EC:6.3.2.17] GO:0019866//organelle inner membrane;GO:0044429 GO:0032550;GO:0016881//acid-amino acid ligase activity GO:0050896//response to stimulus;GO:0007417//central nervous system development;GO:0009887//organ morphogenesis;GO:0009059//macromolecule biosynthetic process;GO:0006760//folic acid-containing compound metabolic process "gi|172088163|ref|NP_034366.2|/0/folylpolyglutamate synthase, mitochondrial precursor [Mus musculus]" 225659 3979 2.103333333 1.683333333 -0.321356617 Down 0.285390575 Cep76 centrosomal protein 76 K16457|1|0.0|1296|mmu:225659|centrosomal protein CEP76 GO:0044444//cytoplasmic part;GO:0005813//centrosome GO:0005488//binding GO:0044772//mitotic cell cycle phase transition;GO:0007099//centriole replication gi|124486733|ref|NP_001074542.1|/0/centrosomal protein of 76 kDa [Mus musculus] 93704 4531 2.133333333 1.713333333 -0.316303546 Down 0.285390575 Pcdhgb7 "protocadherin gamma subfamily B, 7" K16496|1|0.0|1743|mmu:93704|protocadherin gamma subfamily B GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|18087743|ref|NP_291057.1|/0/protocadherin gamma-B7 precursor [Mus musculus] 22022 1852 26.45 28.79 0.122300067 Up 0.285296551 Tpst2 protein-tyrosine sulfotransferase 2 K01021|1|0.0|742|mmu:22022|protein-tyrosine sulfotransferase [EC:2.8.2.20] - - - - 59026 14637 18.87666667 17.27333333 -0.128057514 Down 0.285287149 Huwe1 "HECT, UBA and WWE domain containing 1" K10592|1|0.0|5482|mmu:59026|E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26] - - - gi|146231996|ref|NP_067498.4|/0/E3 ubiquitin-protein ligase HUWE1 [Mus musculus] 194655 3982 5.163333333 4.503333333 -0.197309469 Down 0.285268344 Klf11 Kruppel-like factor 11 K09209|1|0.0|986|mmu:194655|krueppel-like factor 10/11 GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0000975//regulatory region DNA binding;GO:0003700//transcription factor activity, sequence-specific DNA binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0071417//cellular response to organonitrogen compound;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0048534//hematopoietic or lymphoid organ development;GO:0000084//mitotic S phase "gi|148705045|gb|EDL36992.1|/0/TGFB inducible early growth response 3, isoform CRA_a, partial [Mus musculus]" 72787 2576 5.063333333 4.4 -0.20258394 Down 0.285268344 Ndc1 NDC1 transmembrane nucleoporin K14315|1|0.0|1241|mmu:72787|nucleoporin NDC1 GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope GO:0005198//structural molecule activity GO:0006999//nuclear pore organization;GO:0050658//RNA transport;GO:0045184//establishment of protein localization gi|28077005|ref|NP_082631.1|/0/nucleoporin NDC1 [Mus musculus] 72611 2500.24 9.776666667 10.84333333 0.149393751 Up 0.285249539 Zfp655 zinc finger protein 655 K09229|1|8e-54|214|cge:100752055|KRAB and SCAN domains-containing zinc finger protein;K09228|2|3e-19|99.4|mdo:100019298|KRAB domain-containing zinc finger protein GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0005488//binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0006351//transcription, DNA-templated;GO:1901991//negative regulation of mitotic cell cycle phase transition" gi|60360612|dbj|BAD90322.1|/0/mKIAA4222 protein [Mus musculus] 66664 1359 9.47 10.54333333 0.154894724 Up 0.285249539 Tmem41a transmembrane protein 41a - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|12850915|dbj|BAB28894.1|/3.05493e-80/unnamed protein product [Mus musculus] 232441 2254 3.18 2.666666667 -0.253989266 Down 0.285240137 Rerg "RAS-like, estrogen-regulated, growth-inhibitor" K07855|1|2e-93|345|mmu:232441|Ras-related and estrogen-regulated growth inhibitor GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0035258//steroid hormone receptor binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0035258//steroid hormone receptor binding GO:0008283//cell proliferation;GO:0009154//purine ribonucleotide catabolic process;GO:0009719;GO:0016049//cell growth;GO:0035556//intracellular signal transduction;GO:0008283//cell proliferation;GO:0009154//purine ribonucleotide catabolic process;GO:0009719;GO:0016049//cell growth;GO:0035556//intracellular signal transduction gi|255958208|ref|NP_001157686.1|/6.85962e-96/ras-related and estrogen-regulated growth inhibitor isoform b [Mus musculus] 68897 4984.63 3.15 2.64 -0.254813899 Down 0.285240137 Disp1 dispatched homolog 1 (Drosophila) K10649|1|6e-110|402|tsp:Tsp_06730|tripartite motif-containing protein 9/67;K12385|2|3e-18|97.8|pxy:105385759|Niemann-Pick C1 protein;K18730|3|4e-15|87.4|bfo:BRAFLDRAFT_118428|PERQ amino acid-rich with GYF domain-containing protein GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0022892//substrate-specific transporter activity;GO:0004888//transmembrane signaling receptor activity;GO:0022892//substrate-specific transporter activity;GO:0004888//transmembrane signaling receptor activity;GO:0022892//substrate-specific transporter activity;GO:0004888//transmembrane signaling receptor activity;GO:0022892//substrate-specific transporter activity;GO:0004888//transmembrane signaling receptor activity GO:0003002//regionalization;GO:0035638;GO:0042886//amide transport;GO:0009855//determination of bilateral symmetry;GO:0060538//skeletal muscle organ development;GO:0009790//embryo development;GO:0003002//regionalization;GO:0035638;GO:0042886//amide transport;GO:0009855//determination of bilateral symmetry;GO:0060538//skeletal muscle organ development;GO:0009790//embryo development;GO:0003002//regionalization;GO:0035638;GO:0042886//amide transport;GO:0009855//determination of bilateral symmetry;GO:0060538//skeletal muscle organ development;GO:0009790//embryo development;GO:0003002//regionalization;GO:0035638;GO:0042886//amide transport;GO:0009855//determination of bilateral symmetry;GO:0060538//skeletal muscle organ development;GO:0009790//embryo development gi|568911568|ref|XP_006535659.1|/0/PREDICTED: protein dispatched homolog 1 isoform X1 [Mus musculus] 70349 3315 13.29 12.04 -0.142505713 Down 0.285230735 Copb1 "coatomer protein complex, subunit beta 1" K17301|1|0.0|1794|mmu:70349|coatomer subunit beta GO:0030137//COPI-coated vesicle;GO:0030120//vesicle coat GO:0005488//binding GO:0035964//COPI-coated vesicle budding;GO:0015031//protein transport "gi|873090752|pdb|5A1U|G/0/Chain G, The Structure Of The Copi Coat Triad" 15114 3774 0.533333333 0.823333333 0.626439137 Up 0.28521193 Hap1 huntingtin-associated protein 1 K04647|1|0.0|938|mmu:15114|huntingtin-associated protein 1 GO:0033267;GO:0005768//endosome;GO:0033267;GO:0005768//endosome GO:0005515//protein binding;GO:0005515//protein binding GO:0051648//vesicle localization;GO:0016192//vesicle-mediated transport;GO:0070848//response to growth factor;GO:0033036;GO:0010975//regulation of neuron projection development;GO:0051648//vesicle localization;GO:0016192//vesicle-mediated transport;GO:0070848//response to growth factor;GO:0033036;GO:0010975//regulation of neuron projection development gi|30061481|ref|NP_817090.1|/0/huntingtin-associated protein 1 isoform B [Mus musculus] 78921 3878 0.526666667 0.816666667 0.632857191 Up 0.28521193 9130019O22Rik RIKEN cDNA 9130019O22 gene K09228|1|0.0|1152|mmu:78921|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|289666797|ref|NP_084502.2|/0/uncharacterized protein LOC78921 [Mus musculus] 24014 4758 1.026666667 1.38 0.426700417 Up 0.28517432 Rnasel "ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)" K01165|1|0.0|1466|mmu:24014|ribonuclease L GO:0034399//nuclear periphery;GO:0044444//cytoplasmic part GO:0016301//kinase activity;GO:0032550;GO:0043169//cation binding;GO:0004519//endonuclease activity;GO:0003723//RNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0019079//viral genome replication;GO:0019221//cytokine-mediated signaling pathway;GO:0006396//RNA processing;GO:0002252;GO:0006464//cellular protein modification process;GO:0042254//ribosome biogenesis gi|31982957|ref|NP_036012.1|/0/2-5A-dependent ribonuclease [Mus musculus] 74754 4028 1.02 1.37 0.425606741 Up 0.28517432 Dhcr24 24-dehydrocholesterol reductase K09828|1|0.0|1071|mmu:74754|Delta24-sterol reductase [EC:1.3.1.72 1.3.1.-] - - - - 66167 637 63.79333333 68.95666667 0.112284373 Up 0.285136711 Tma7 translational machinery associated 7 - - - - gi|344250870|gb|EGW06974.1|/1.1271e-09/Coiled-coil domain-containing protein 72 [Cricetulus griseus] 105859 2507 64.16666667 69.29666667 0.110961917 Up 0.285089699 Csdc2 "cold shock domain containing C2, RNA binding" K15441|1|1e-20|104|tsp:Tsp_04322|tRNA-specific adenosine deaminase 2 [EC:3.5.4.-];K00503|2|4e-07|59.7|pxy:105395691|dopamine beta-monooxygenase [EC:1.14.17.1] - - - gi|6114756|emb|CAA62001.2|/3.97161e-111/PIPPin protein [Rattus norvegicus] 672763 830 0.183333333 0.4 1.125530882 Up 0.285070894 Gm13710 predicted gene 13710 - - - - "gi|148695338|gb|EDL27285.1|/1.78003e-58/mCG1040586, partial [Mus musculus]" 68942 1838 18.24 16.64666667 -0.131872409 Down 0.285070894 Chmp2b charged multivesicular body protein 2B K12192|1|1e-86|323|oas:101121224|charged multivesicular body protein 2B GO:0005770//late endosome GO:0005515//protein binding GO:0044765//single-organism transport;GO:0044763;GO:0045184//establishment of protein localization gi|742182033|ref|XP_010853139.1|/7.95868e-87/PREDICTED: charged multivesicular body protein 2b isoform X1 [Bison bison bison] 227736 1675 0.3 0.55 0.874469118 Up 0.285023882 Cfap157 cilia and flagella associated protein 157 K16476|1|7e-12|74.7|phi:102113078|ninein;K20283|3|3e-11|72.8|mcf:101926555|golgin subfamily A member 4 - - - - 16508 4562 2.893333333 3.426666667 0.244073317 Up 0.28497687 Kcnd2 "potassium voltage-gated channel, Shal-related family, member 2" K04892|1|0.0|1140|mmu:16508|potassium voltage-gated channel Shal-related subfamily D member 2 - - - gi|26006243|dbj|BAC41464.1|/0/mKIAA1044 protein [Mus musculus] 723954 104 2.856666667 3.383333333 0.244112618 Up 0.28497687 Mir133a-2 microRNA 133a-2 - - - - - 230766 957 0.47 0.753333333 0.68062761 Up 0.284967468 Fam167b "family with sequence similarity 167, member B" - - - - - 66462 657 60.97 66.02 0.114803593 Up 0.284948663 2810428I15Rik RIKEN cDNA 2810428I15 gene - - - - - 100041530 1990 0.036666667 0.203333333 2.471305719 Up 0.284854639 Gm10409 predicted pseudogene 8348 "K03844|1|3e-18|96.3|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - gi|755546841|ref|XP_011243026.1|/2.67327e-127/PREDICTED: predicted gene 3264 isoform X1 [Mus musculus] 320872 1761 0.073333333 0.266666667 1.862496476 Up 0.284845237 Arhgap15os "Rho GTPase activating protein 15, opposite strand" - - - - gi|148694911|gb|EDL26858.1|/2.82334e-17/mCG1051059 [Mus musculus] 217057 2973.41 3.446666667 4.026666667 0.224384269 Up 0.28461958 Ptrh2 peptidyl-tRNA hydrolase 2 "K04794|1|7e-99|364|mmu:217057|peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29]" GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0052689//carboxylic ester hydrolase activity;GO:0005488//binding;GO:0052689//carboxylic ester hydrolase activity GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process "gi|149363634|ref|NP_001092280.1|/6.07918e-98/peptidyl-tRNA hydrolase 2, mitochondrial isoform b [Mus musculus]" 100038538 1652 0.043333333 0.216666667 2.321928095 Up 0.284610177 Gm10767 predicted gene 10767 K18708|1|1e-50|203|mmu:67148|RNMT-activating mini protein GO:0034518//RNA cap binding complex;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0006370//7-methylguanosine mRNA capping gi|21313122|ref|NP_080273.1|/1.15581e-49/RNMT-activating mini protein [Mus musculus] 75205 1527 1.576666667 1.983333333 0.331049485 Up 0.284534958 4930533N22Rik RIKEN cDNA 4930533N22 gene - - - - - 15458 1489 0.136666667 0.01 -3.772589504 Down 0.284497349 Hpx hemopexin K18977|1|0.0|989|mmu:15458|hemopexin [EC:3.2.1.35] GO:0044421 GO:0043169//cation binding;GO:0046906//tetrapyrrole binding GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0051234//establishment of localization;GO:0006778//porphyrin-containing compound metabolic process;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0002377//immunoglobulin production;GO:0034341//response to interferon-gamma;GO:0042508//tyrosine phosphorylation of Stat1 protein gi|160358829|ref|NP_059067.2|/0/hemopexin precursor [Mus musculus] 319146 1462 0.01 0.136666667 3.772589504 Up 0.284497349 Ifnz interferon zeta K05414|1|2e-38|162|cge:100763520|interferon alpha GO:0044421 GO:0005102//receptor binding GO:0007166//cell surface receptor signaling pathway;GO:0030098//lymphocyte differentiation;GO:0002252;GO:0007049//cell cycle;GO:0012501//programmed cell death gi|37497122|ref|NP_922871.1|/2.45933e-101/interferon zeta precursor [Mus musculus] 21748 397 0.136666667 0.01 -3.772589504 Down 0.284497349 Terc telomerase RNA component - - - - "gi|148706940|gb|EDL38887.1|/6.72461e-39/mCG140524, partial [Mus musculus]" 382075 1080 0.01 0.136666667 3.772589504 Up 0.284497349 Odf3l1 outer dense fiber of sperm tails 3-like 1 - - - - gi|568961648|ref|XP_006511311.1|/1.21866e-170/PREDICTED: outer dense fiber protein 3-like protein 1 isoform X2 [Mus musculus] 545378 399 0.01 0.136666667 3.772589504 Up 0.284497349 Sh2d1b2 SH2 domain containing 1B2 K07989|1|1e-61|236|mmu:26904|EWS/FLI1 activated transcript 2 GO:0044464 "GO:0060090//binding, bridging;GO:0045309//protein phosphorylated amino acid binding" GO:0001934//positive regulation of protein phosphorylation;GO:0002228//natural killer cell mediated immunity;GO:0002767//immune response-inhibiting cell surface receptor signaling pathway;GO:0030101//natural killer cell activation;GO:0001818//negative regulation of cytokine production;GO:0001911;GO:0002263//cell activation involved in immune response;GO:0001933//negative regulation of protein phosphorylation;GO:0031349//positive regulation of defense response gi|75677448|ref|NP_001028671.1|/5.43712e-73/SH2 domain-containing protein 1B2 [Mus musculus] 19120 407 0.01 0.136666667 3.772589504 Up 0.284497349 Prm3 protamine 3 - GO:0043229//intracellular organelle - GO:0048870//cell motility;GO:0032502//developmental process;GO:0032501//multicellular organismal process gi|114326495|ref|NP_038666.2|/5.28962e-36/protamine-3 [Mus musculus] 17086 1463 0.01 0.136666667 3.772589504 Up 0.284497349 Ncr1 natural cytotoxicity triggering receptor 1 K06741|1|0.0|649|mmu:17086|natural cytotoxicity triggering receptor 1;K06512|3|3e-130|468|cge:100767032|leukocyte immunoglobulin-like receptor GO:0031224//intrinsic component of membrane;GO:0090544//BAF-type complex GO:0004871//signal transducer activity GO:0046649//lymphocyte activation;GO:0001910//regulation of leukocyte mediated cytotoxicity;GO:0006952//defense response;GO:0007154//cell communication gi|31981638|ref|NP_034876.2|/0/natural cytotoxicity triggering receptor 1 precursor [Mus musculus] 54368 811 0.136666667 0.01 -3.772589504 Down 0.284497349 Gp9 glycoprotein 9 (platelet) K06263|1|3e-96|353|mmu:54368|platelet glycoprotein IX GO:0031224//intrinsic component of membrane - GO:0022610;GO:0007599//hemostasis gi|568942436|ref|XP_006506457.1|/1.28821e-106/PREDICTED: platelet glycoprotein IX isoform X2 [Mus musculus] 17428 4601 7.496666667 6.663333333 -0.170005189 Down 0.284469141 Mnt max binding protein K09115|1|0.0|721|mmu:17428|MAX-binding protein GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0007049//cell cycle;GO:0006915//apoptotic process;GO:0007568//aging;GO:0006351//transcription, DNA-templated" gi|162287033|ref|NP_034943.3|/0/max-binding protein MNT [Mus musculus] 13587 716 0.146666667 0.36 1.295455884 Up 0.284450337 Ear2 "eosinophil-associated, ribonuclease A family, member 2" K01168|1|4e-42|173|rno:474169|pancreatic ribonuclease [EC:3.1.27.5];K10787|2|6e-41|169|rno:100361866|eosinophil cationic protein [EC:3.1.27.-] - - - - 72795 3412.56 12.48666667 13.71666667 0.135541531 Up 0.284440934 Ttc19 tetratricopeptide repeat domain 19 "K18169|1|1e-168|596|mmu:72795|tetratricopeptide repeat protein 19, mitochondrial" GO:0019866//organelle inner membrane;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding GO:0044763;GO:0017062//respiratory chain complex III assembly;GO:0044763;GO:0017062//respiratory chain complex III assembly "gi|110347537|ref|NP_082636.3|/7.02715e-178/tetratricopeptide repeat protein 19, mitochondrial isoform 1 [Mus musculus]" 104110 3414 13.42 12.18666667 -0.139081102 Down 0.284440934 Adcy4 adenylate cyclase 4 K08044|1|0.0|1895|mmu:104110|adenylate cyclase 4 [EC:4.6.1.1] GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0044424;GO:0031224//intrinsic component of membrane GO:0032550;GO:0043169//cation binding;GO:0016829//lyase activity;GO:0032403//protein complex binding;GO:0009975//cyclase activity "GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0045762//positive regulation of adenylate cyclase activity" gi|17978250|ref|NP_536683.1|/0/adenylate cyclase type 4 [Mus musculus] 54195 3251 6.296666667 5.54 -0.18470232 Down 0.284168265 Gucy1b3 "guanylate cyclase 1, soluble, beta 3" K12319|1|0.0|1127|mmu:54195|guanylate cyclase soluble subunit beta [EC:4.6.1.2] GO:0043234//protein complex;GO:0043227//membrane-bounded organelle;GO:0044424;GO:0043234//protein complex;GO:0043227//membrane-bounded organelle;GO:0044424 GO:0043169//cation binding;GO:0046906//tetrapyrrole binding;GO:0032550;GO:0031072//heat shock protein binding;GO:0016829//lyase activity;GO:0009975//cyclase activity;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0046906//tetrapyrrole binding;GO:0032550;GO:0031072//heat shock protein binding;GO:0016829//lyase activity;GO:0009975//cyclase activity;GO:0046983//protein dimerization activity GO:0019932//second-messenger-mediated signaling;GO:0009152//purine ribonucleotide biosynthetic process;GO:0007599//hemostasis;GO:0003013//circulatory system process;GO:0019932//second-messenger-mediated signaling;GO:0009152//purine ribonucleotide biosynthetic process;GO:0007599//hemostasis;GO:0003013//circulatory system process "gi|148683488|gb|EDL15435.1|/0/guanylate cyclase 1, soluble, beta 3, isoform CRA_a, partial [Mus musculus]" 71302 7899 8.846666667 7.913333333 -0.160848436 Down 0.284121253 Arhgap26 Rho GTPase activating protein 26 K20071|1|0.0|1390|mmu:71302|Rho GTPase-activating protein 26 - - - - 208366 2736 1.3 1.683333333 0.372809264 Up 0.284102448 Rpp40 ribonuclease P 40 subunit K14530|1|0.0|756|mmu:208366|ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5] - - - gi|172072663|ref|NP_666050.3|/0/ribonuclease P protein subunit p40 [Mus musculus] 14560 2613 1.92 1.516666667 -0.340202266 Down 0.284083644 Gdf10 growth differentiation factor 10 K05496|1|0.0|923|mmu:14560|bone morphogenetic protein 3/3B GO:0044421 GO:0005102//receptor binding GO:0001649//osteoblast differentiation;GO:0044702//single organism reproductive process;GO:0009719;GO:0022037//metencephalon development "gi|148692914|gb|EDL24861.1|/0/growth differentiation factor 10, partial [Mus musculus]" 13717 3865 27.28666667 25.04 -0.123961604 Down 0.284046034 Eln elastin K14211|1|1e-35|155|ngi:103746269|elastin - - - - 76884 6397.61 25.94 28.19 0.120004998 Up 0.284046034 Cyfip2 cytoplasmic FMR1 interacting protein 2 K05749|1|0.0|2507|oas:101113147|cytoplasmic FMR1 interacting protein GO:0044444//cytoplasmic part;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0042995//cell projection GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0007155//cell adhesion;GO:0012501//programmed cell death;GO:0006508//proteolysis;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0007155//cell adhesion;GO:0012501//programmed cell death;GO:0006508//proteolysis;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0007155//cell adhesion;GO:0012501//programmed cell death;GO:0006508//proteolysis gi|39104558|dbj|BAC41472.2|/0/mKIAA1168 protein [Mus musculus] 217012 3677 61.29 66 0.10681432 Up 0.284036632 Unc45b unc-45 myosin chaperone B K19870|1|4e-11|73.6|hst:105185073|sperm-associated antigen 1;K17766|2|9e-11|72.4|lcm:102355409|mitochondrial import receptor subunit TOM34;K04460|3|2e-10|71.2|xtr:493275|serine/threonine-protein phosphatase 5 [EC:3.1.3.16] GO:0044444//cytoplasmic part GO:0031072//heat shock protein binding GO:0006457//protein folding;GO:0048513//animal organ development;GO:0048869//cellular developmental process gi|264681528|ref|NP_848795.3|/0/protein unc-45 homolog B [Mus musculus] 69106 2029.02 4.47 5.12 0.195868979 Up 0.283999022 Stoml1 stomatin-like 1 K17286|1|4e-24|115|dvi:Dvir_GJ19367|erythrocyte band 7 integral membrane protein GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005496//steroid binding;GO:0005496//steroid binding - gi|255522836|ref|NP_081218.3|/0/stomatin-like protein 1 [Mus musculus] 66356 5331.6 4.973333333 4.32 -0.203181817 Down 0.283999022 Knop1 lysine rich nucleolar protein 1 - - - - gi|158966725|ref|NP_075686.2|/0/lysine-rich nucleolar protein 1 isoform 1 [Mus musculus] 73945 7327 4.416666667 5.07 0.199027793 Up 0.283999022 Otud4 OTU domain containing 4 K13718|1|0.0|2029|mmu:73945|OTU domain-containing protein 4 [EC:3.4.19.12] - - - gi|365733608|ref|NP_001242962.1|/0/OTU domain-containing protein 4 isoform 1 [Mus musculus] 227682 3987.07 4.92 4.273333333 -0.203296459 Down 0.283999022 Trub2 TruB pseudouridine (psi) synthase family member 2 K03177|1|7e-40|107|xtr:496499|tRNA pseudouridine55 synthase [EC:5.4.99.25] - GO:0016866//intramolecular transferase activity;GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0003676//nucleic acid binding GO:0006399//tRNA metabolic process;GO:0010467//gene expression;GO:0009451//RNA modification;GO:0006399//tRNA metabolic process;GO:0010467//gene expression;GO:0009451//RNA modification;GO:0006399//tRNA metabolic process;GO:0010467//gene expression;GO:0009451//RNA modification;GO:0006399//tRNA metabolic process;GO:0010467//gene expression;GO:0009451//RNA modification gi|224994213|ref|NP_663495.3|/0/probable tRNA pseudouridine synthase 2 isoform a [Mus musculus] 55949 1933 57.82666667 62.52 0.112582836 Up 0.283942608 Eef1b2 eukaryotic translation elongation factor 1 beta 2 K03232|1|1e-93|346|mmu:55949|elongation factor 1-beta GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0008135//translation factor activity, RNA binding" GO:0006412//translation "gi|24586721|gb|AAH39635.1|/3.20267e-102/eukaryotic translation elongation factor 1 beta 2, partial [Mus musculus]" 66541 955 58.89666667 63.57333333 0.11023575 Up 0.283942608 Immp1l IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) K09647|1|4e-99|363|umr:103659353|mitochondrial inner membrane protease subunit 1 [EC:3.4.21.-] GO:0005743//mitochondrial inner membrane "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0006626//protein targeting to mitochondrion;GO:0019538//protein metabolic process gi|670988124|ref|XP_008685082.1|/2.98278e-98/PREDICTED: mitochondrial inner membrane protease subunit 1 isoform X1 [Ursus maritimus] 219150 2931 1.076666667 0.76 -0.502500341 Down 0.283914401 Hmbox1 homeobox containing 1 "K08034|1|3e-12|77.0|cmk:103183325|transcription factor 2, hepatocyte nuclear factor 1-beta;K08036|3|2e-11|74.3|pbi:103054191|transcription factor 1, hepatocyte nuclear factor 1-alpha" GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated" "gi|148704093|gb|EDL36040.1|/0/homeobox containing 1, isoform CRA_b, partial [Mus musculus]" 231123 1980 0.766666667 1.083333333 0.498805857 Up 0.283914401 Haus3 "HAUS augmin-like complex, subunit 3" K16586|1|0.0|1122|mmu:231123|HAUS augmin-like complex subunit 3 GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex - GO:0006461//protein complex assembly;GO:0031023//microtubule organizing center organization;GO:0000087//mitotic M phase gi|22122693|ref|NP_666271.1|/0/HAUS augmin-like complex subunit 3 [Mus musculus] 16176 1348 0.146666667 0.353333333 1.268488836 Up 0.283829779 Il1b interleukin 1 beta K04519|1|4e-156|553|mmu:16176|interleukin 1 beta - - - - 16581 3143 2.4 2.88 0.263034406 Up 0.283801572 Kifc2 kinesin family member C2 K10406|1|0.0|1220|mmu:16581|kinesin family member C2/C3 GO:0015630//microtubule cytoskeleton GO:0003774//motor activity;GO:0032550 GO:0006928//movement of cell or subcellular component gi|1928995|gb|AAB51397.1|/0/kinesin motor protein [Mus musculus] 242700 4012 1.436666667 1.08 -0.411694056 Down 0.283801572 Ifnlr1 interferon lambda receptor 1 K05140|1|0.0|895|mmu:242700|interleukin 28 receptor alpha - - - - 94280 2974 7.186666667 6.37 -0.1740294 Down 0.283622927 Sfxn3 sideroflexin 3 K03351|1|1e-93|347|smm:Smp_136960|anaphase-promoting complex subunit 4;K02542|2|3e-13|80.5|pxy:105395647|DNA replication licensing factor MCM6 [EC:3.6.4.12] GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane;GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity GO:0044763;GO:0055080//cation homeostasis;GO:0006811//ion transport;GO:0044763;GO:0055080//cation homeostasis;GO:0006811//ion transport gi|295821210|ref|NP_001171483.1|/4.17259e-152/sideroflexin-3 isoform 2 [Mus musculus] 70237 2837.56 3.97 4.576666667 0.205158212 Up 0.283604122 Bhlhb9 "basic helix-loop-helix domain containing, class B9" - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - "gi|148691893|gb|EDL23840.1|/0/mCG114181, isoform CRA_a, partial [Mus musculus]" 74585 2817 11.47666667 12.68666667 0.144609381 Up 0.283538305 Sppl3 signal peptide peptidase 3 K09598|1|0.0|639|ngi:103740130|signal peptide peptidase-like 3 [EC:3.4.23.-] GO:0000139//Golgi membrane;GO:0030176//integral component of endoplasmic reticulum membrane GO:0042802//identical protein binding;GO:0004190//aspartic-type endopeptidase activity GO:0033619//membrane protein proteolysis gi|674034482|ref|XP_008838904.1|/1.21539e-180/PREDICTED: signal peptide peptidase-like 3 [Nannospalax galili] 320197 2357 1.193333333 0.86 -0.472588522 Down 0.283491293 D830046C22Rik RIKEN cDNA D830046C22 gene - - - - gi|187955654|gb|AAI47359.1|/9.19145e-78/RIKEN cDNA D830046C22 gene [Mus musculus] 78329 379 0.843333333 1.17 0.472333646 Up 0.283491293 2310010J17Rik RIKEN cDNA 2310010J17 gene - - - - - 233575 2033.28 26.15333333 28.36333333 0.117032257 Up 0.283481891 Pgap2 post-GPI attachment to proteins 2 K15263|1|4e-17|92.8|bmy:Bm1_03965|cell growth-regulating nucleolar protein GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0005488//binding;GO:0022892//substrate-specific transporter activity;GO:0005488//binding;GO:0022892//substrate-specific transporter activity;GO:0005488//binding;GO:0022892//substrate-specific transporter activity;GO:0005488//binding;GO:0022892//substrate-specific transporter activity GO:0035556//intracellular signal transduction;GO:0006915//apoptotic process;GO:0033554//cellular response to stress;GO:0045184//establishment of protein localization;GO:0006497//protein lipidation;GO:0035556//intracellular signal transduction;GO:0006915//apoptotic process;GO:0033554//cellular response to stress;GO:0045184//establishment of protein localization;GO:0006497//protein lipidation;GO:0035556//intracellular signal transduction;GO:0006915//apoptotic process;GO:0033554//cellular response to stress;GO:0045184//establishment of protein localization;GO:0006497//protein lipidation;GO:0035556//intracellular signal transduction;GO:0006915//apoptotic process;GO:0033554//cellular response to stress;GO:0045184//establishment of protein localization;GO:0006497//protein lipidation "gi|148684644|gb|EDL16591.1|/1.32836e-58/FGF receptor activating protein 1, isoform CRA_d [Mus musculus]" 84004 2892 26.97333333 24.77333333 -0.122745818 Down 0.283387867 Mcam melanoma cell adhesion molecule K06534|1|0.0|1199|mmu:84004|melanoma cell adhesion molecule GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0043025//neuronal cell body - GO:0016337//single organismal cell-cell adhesion;GO:0060055//angiogenesis involved in wound healing;GO:0097205//renal filtration gi|160333901|ref|NP_075548.2|/0/cell surface glycoprotein MUC18 precursor [Mus musculus] 106931 3247.06 5.696666667 6.446666667 0.178435398 Up 0.283331453 Kctd1 potassium channel tetramerisation domain containing 1 "K03849|1|7e-22|108|cmk:103177229|alpha-1,3-glucosyltransferase [EC:2.4.1.265];K09672|2|1e-17|94.0|tru:101061394|carbohydrate 4-sulfotransferase 8 [EC:2.8.2.-];K15074|3|1e-09|67.4|cbr:CBG18386|BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein;K11835|4|2e-09|66.6|sko:100377510|ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.4.19.12]" GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0005515//protein binding "GO:0051259//protein oligomerization;GO:0006351//transcription, DNA-templated" "gi|119621629|gb|EAX01224.1|/2.55184e-159/potassium channel tetramerisation domain containing 1, isoform CRA_c [Homo sapiens]" 66885 3348 25.10333333 27.29666667 0.120845843 Up 0.283293843 Acadsb "acyl-Coenzyme A dehydrogenase, short/branched chain" K09478|1|0.0|859|mmu:66885|short/branched chain acyl-CoA dehydrogenase [EC:1.3.99.12] - - - - 75782 4235 0.51 0.266666667 -0.935459748 Down 0.283228027 Lca5 Leber congenital amaurosis 5 (human) K11515|1|9e-07|58.2|shr:100929011|inner centromere protein;K06675|2|1e-06|57.8|apla:101803192|structural maintenance of chromosome 4;K20478|4|2e-06|57.0|sko:100377934|golgin subfamily B member 1 GO:0005815//microtubule organizing center;GO:0005930//axoneme;GO:0005815//microtubule organizing center;GO:0005930//axoneme GO:0005515//protein binding;GO:0005515//protein binding GO:0010970//transport along microtubule;GO:0045184//establishment of protein localization;GO:0007601//visual perception;GO:0010970//transport along microtubule;GO:0045184//establishment of protein localization;GO:0007601//visual perception "gi|148694514|gb|EDL26461.1|/0/RIKEN cDNA 4930431B11, isoform CRA_b, partial [Mus musculus]" 28109 3535 2.65 3.153333333 0.250885323 Up 0.283228027 D10Wsu102e "DNA segment, Chr 10, Wayne State University 102, expressed" - - - - gi|44662811|ref|NP_080855.1|/6.57402e-78/uncharacterized protein C12orf45 homolog [Mus musculus] 214459 5203 3.15 2.65 -0.249359469 Down 0.283228027 Fnbp1l formin binding protein 1-like K20121|1|0.0|1093|bta:616665|formin-binding protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0005488//binding GO:0048731//system development;GO:0016192//vesicle-mediated transport;GO:0044248;GO:0048869//cellular developmental process gi|167900466|ref|NP_001108137.1|/0/formin-binding protein 1-like isoform 1 [Mus musculus] 21749 2181 2.266666667 1.836666667 -0.303482428 Down 0.283152808 Terf1 telomeric repeat binding factor 1 K11110|1|0.0|809|mmu:21749|telomeric repeat-binding factor 1 GO:0000782//telomere cap complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0000782//telomere cap complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0046983//protein dimerization activity;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0015631//tubulin binding;GO:0003690//double-stranded DNA binding;GO:0004857//enzyme inhibitor activity;GO:0046983//protein dimerization activity;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0015631//tubulin binding;GO:0003690//double-stranded DNA binding;GO:0004857//enzyme inhibitor activity GO:0042221//response to chemical;GO:0001304;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0006915//apoptotic process;GO:0051259//protein oligomerization;GO:0031112;GO:0012502//induction of programmed cell death;GO:0051348//negative regulation of transferase activity;GO:0007004//telomere maintenance via telomerase;GO:0042221//response to chemical;GO:0001304;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0006915//apoptotic process;GO:0051259//protein oligomerization;GO:0031112;GO:0012502//induction of programmed cell death;GO:0051348//negative regulation of transferase activity;GO:0007004//telomere maintenance via telomerase gi|6678287|ref|NP_033378.1|/0/telomeric repeat-binding factor 1 isoform 1 [Mus musculus] 80286 1527 9.366666667 10.39666667 0.150513422 Up 0.283105796 Tusc3 tumor suppressor candidate 3 K12669|1|8e-167|589|mmu:80286|oligosaccharyltransferase complex subunit gamma GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane GO:0004576//oligosaccharyl transferase activity;GO:0046873//metal ion transmembrane transporter activity GO:0019725//cellular homeostasis;GO:0070838//divalent metal ion transport;GO:0050877//neurological system process;GO:0006487//protein N-linked glycosylation gi|507546395|ref|XP_004657154.1|/6.70732e-166/PREDICTED: tumor suppressor candidate 3 isoform X2 [Jaculus jaculus] 23797 4735 4.016666667 3.443333333 -0.222192892 Down 0.283096393 Akt3 thymoma viral proto-oncogene 3 K04456|1|0.0|989|mmu:23797|RAC serine/threonine-protein kinase [EC:2.7.11.1] GO:0031981//nuclear lumen;GO:0016020//membrane GO:0032550;GO:0004672//protein kinase activity;GO:0008289//lipid binding;GO:0019901//protein kinase binding GO:0006468//protein phosphorylation;GO:0002028//regulation of sodium ion transport;GO:0007005//mitochondrion organization;GO:0032868//response to insulin;GO:0007154//cell communication gi|190883484|ref|NP_035915.3|/0/RAC-gamma serine/threonine-protein kinase [Mus musculus] 13205 4571 27.16666667 24.98666667 -0.120679106 Down 0.283086991 Ddx3x "DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked" K11594|1|0.0|1041|mmu:13205|ATP-dependent RNA helicase DDX3X [EC:3.6.4.13] GO:0031966//mitochondrial membrane;GO:0035770//ribonucleoprotein granule "GO:0031369//translation initiation factor binding;GO:0003678//DNA helicase activity;GO:0003729//mRNA binding;GO:0003724//RNA helicase activity;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0043021//ribonucleoprotein complex binding" GO:0046685//response to arsenic-containing substance;GO:0006461//protein complex assembly;GO:0006952//defense response;GO:0016049//cell growth;GO:0097193//intrinsic apoptotic signaling pathway;GO:0006970//response to osmotic stress;GO:0006413//translational initiation;GO:0009154//purine ribonucleotide catabolic process;GO:0097191//extrinsic apoptotic signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:1901992//positive regulation of mitotic cell cycle phase transition;GO:0042255//ribosome assembly;GO:0051707//response to other organism gi|62087546|dbj|BAD92220.1|/0/DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 variant [Homo sapiens] 22117 1096 12.72666667 11.52666667 -0.142879234 Down 0.283049381 Tst "thiosulfate sulfurtransferase, mitochondrial" K01011|1|9e-175|615|mmu:22117|thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] GO:0019866//organelle inner membrane;GO:0044429 GO:0016783//sulfurtransferase activity;GO:0019843//rRNA binding GO:0009058//biosynthetic process;GO:0035927//RNA import into mitochondrion gi|6678449|ref|NP_033463.1|/7.06375e-174/thiosulfate sulfurtransferase [Mus musculus] 14088 3073.55 0.946666667 1.286666667 0.442709918 Up 0.283039979 Fancc "Fanconi anemia, complementation group C" K10890|1|0.0|1048|mmu:14088|fanconi anemia group C protein GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part - GO:0006281//DNA repair;GO:0006801//superoxide metabolic process;GO:0002376//immune system process;GO:0019953//sexual reproduction;GO:0003006//developmental process involved in reproduction;GO:0006281//DNA repair;GO:0006801//superoxide metabolic process;GO:0002376//immune system process;GO:0019953//sexual reproduction;GO:0003006//developmental process involved in reproduction;GO:0006281//DNA repair;GO:0006801//superoxide metabolic process;GO:0002376//immune system process;GO:0019953//sexual reproduction;GO:0003006//developmental process involved in reproduction gi|74150968|dbj|BAE27618.1|/0/unnamed protein product [Mus musculus] 213948 3902 0.95 1.29 0.441371647 Up 0.283039979 Atg9b autophagy related 9B K17907|1|0.0|1412|mmu:213948|autophagy-related protein 9 GO:0005773//vacuole;GO:0031982//vesicle;GO:0031224//intrinsic component of membrane - GO:0044248;GO:0007033//vacuole organization gi|146219845|ref|NP_001002897.2|/0/autophagy-related protein 9B [Mus musculus] 434064 1423 0.306666667 0.103333333 -1.569365646 Down 0.282974162 Gm5577 predicted gene 5577 - - - - - 69178 2445.51 25.69666667 27.86333333 0.116786633 Up 0.282955357 Snx5 sorting nexin 5 K17920|1|0.0|796|mmu:69178|sorting nexin-5/6/32 GO:0005769//early endosome;GO:0031252//cell leading edge;GO:0012506//vesicle membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0010008//endosome membrane;GO:0042995//cell projection;GO:0005769//early endosome;GO:0031252//cell leading edge;GO:0012506//vesicle membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0010008//endosome membrane;GO:0042995//cell projection GO:0005543//phospholipid binding;GO:0005543//phospholipid binding GO:0044763;GO:0045184//establishment of protein localization;GO:0006897//endocytosis;GO:0044763;GO:0045184//establishment of protein localization;GO:0006897//endocytosis gi|504146547|ref|XP_004585690.1|/0/PREDICTED: sorting nexin-5 [Ochotona princeps] 109246 3930 25.40333333 27.57 0.118081453 Up 0.282955357 Tspan9 tetraspanin 9 K17350|1|1e-127|460|ngi:103727551|tetraspanin-9 - - - gi|568940233|ref|XP_006505395.1|/3.49769e-128/PREDICTED: tetraspanin-9 isoform X3 [Mus musculus] 22751 2632 1.25 1.623333333 0.377031177 Up 0.282861334 Zfp90 zinc finger protein 90 K09228|1|0.0|1317|mmu:22751|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle "GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding" "GO:0051100//negative regulation of binding;GO:0006351//transcription, DNA-templated" "gi|148679418|gb|EDL11365.1|/0/zinc finger protein 90, isoform CRA_b, partial [Mus musculus]" 114713 5699 0.633333333 0.936666667 0.564570712 Up 0.282861334 Rasa2 RAS p21 protein activator 2 K08053|1|0.0|1593|mmu:114713|Ras GTPase-activating protein 2 - - - gi|13161333|dbj|BAB32975.1|/0/GAP1m [Mus musculus] 66611 1512 0.686666667 0.42 -0.709220604 Down 0.282842529 Ribc1 RIB43A domain with coiled-coils 1 - - - - gi|13385124|ref|NP_079936.1|/4.47162e-154/RIB43A-like with coiled-coils protein 1 [Mus musculus] 57248 878 1.103333333 0.783333333 -0.49417046 Down 0.282786115 Ly6i "lymphocyte antigen 6 complex, locus I" K06846|1|8e-68|259|mmu:57248|lymphocyte antigen 6 complex locus protein D/E/G6/H GO:0009986//cell surface;GO:0031224//intrinsic component of membrane - - gi|257096069|ref|NP_065244.2|/6.82177e-67/lymphocyte antigen 6I precursor [Mus musculus] 195531 1256 0.766666667 0.49 -0.645817706 Down 0.282776712 Gm13152 zinc finger protein 982 K09228|1|0.0|799|mmu:195531|KRAB domain-containing zinc finger protein - - - gi|85861192|ref|NP_001034298.1|/0/uncharacterized protein LOC195531 [Mus musculus] 53892 2911 6.34 7.146666667 0.17278766 Up 0.282748505 Ppm1d "protein phosphatase 1D magnesium-dependent, delta isoform" K10147|1|0.0|1099|mmu:53892|protein phosphatase 1D [EC:3.1.3.16] - GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity GO:0044772//mitotic cell cycle phase transition;GO:0051707//response to other organism;GO:0006470//protein dephosphorylation gi|74180575|dbj|BAE34209.1|/0/unnamed protein product [Mus musculus] 94092 3896 1.653333333 2.063333333 0.319599289 Up 0.282739103 Trim16 tripartite motif-containing 16 K12006|1|0.0|1099|mmu:94092|tripartite motif-containing protein 16 - - - gi|70778828|ref|NP_444399.2|/0/tripartite motif-containing protein 16 [Mus musculus] 229543 4460 12.67 11.47666667 -0.142712844 Down 0.282692091 Ints3 integrator complex subunit 3 K13140|1|0.0|1827|mmu:229543|integrator complex subunit 3 "GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0016591//DNA-directed RNA polymerase II, holoenzyme" - GO:0006259//DNA metabolic process;GO:0009314//response to radiation;GO:0033554//cellular response to stress;GO:0016073//snRNA metabolic process;GO:0006259//DNA metabolic process;GO:0009314//response to radiation;GO:0033554//cellular response to stress;GO:0016073//snRNA metabolic process "gi|148683196|gb|EDL15143.1|/0/integrator complex subunit 3, isoform CRA_b [Mus musculus]" 26380 4284.06 16.55333333 18.05333333 0.125143477 Up 0.282494641 Esrrb "estrogen related receptor, beta" K08553|1|0.0|823|mmu:26380|estrogen-related receptor beta GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0008289//lipid binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0008289//lipid binding GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0000904//cell morphogenesis involved in differentiation;GO:0001832//blastocyst growth;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0000904//cell morphogenesis involved in differentiation;GO:0001832//blastocyst growth gi|226958365|ref|NP_036064.3|/0/steroid hormone receptor ERR2 isoform 1 [Mus musculus] 13008 889 16.49 17.99 0.125603788 Up 0.282494641 Csrp2 cysteine and glycine-rich protein 2 K09377|1|1e-102|374|umr:103656910|cysteine and glycine-rich protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding GO:0042692//muscle cell differentiation gi|78214352|ref|NP_803174.2|/1.12571e-101/cysteine and glycine-rich protein 2 [Rattus norvegicus] 22241 5215 52.22 56.45333333 0.112456311 Up 0.282485238 Ulk1 unc-51 like kinase 1 K08269|1|0.0|1783|mmu:22241|serine/threonine-protein kinase ULK/ATG1 [EC:2.7.11.1] GO:0012506//vesicle membrane;GO:0005773//vacuole;GO:0044297//cell body;GO:0000407//pre-autophagosomal structure;GO:0043234//protein complex;GO:0042995//cell projection GO:0032550;GO:0004672//protein kinase activity;GO:0017016//Ras GTPase binding;GO:0019900//kinase binding GO:0033036;GO:0010508//positive regulation of autophagy;GO:0021932;GO:0006898//receptor-mediated endocytosis;GO:0021533//cell differentiation in hindbrain;GO:0007409//axonogenesis;GO:0007033//vacuole organization;GO:0007264//small GTPase mediated signal transduction;GO:0006468//protein phosphorylation;GO:0030308//negative regulation of cell growth;GO:0009966//regulation of signal transduction;GO:0033554//cellular response to stress;GO:0031667//response to nutrient levels "gi|148688054|gb|EDL20001.1|/0/Unc-51 like kinase 1 (C. elegans), isoform CRA_a, partial [Mus musculus]" 140499 3405.6 9.423333333 10.44 0.147812329 Up 0.282475836 Ube2j2 ubiquitin-conjugating enzyme E2J 2 K04554|1|5e-136|488|rno:298689|ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0019787//ubiquitin-like protein transferase activity;GO:0032550;GO:0019787//ubiquitin-like protein transferase activity;GO:0032550;GO:0019787//ubiquitin-like protein transferase activity;GO:0032550;GO:0019787//ubiquitin-like protein transferase activity;GO:0032550;GO:0019787//ubiquitin-like protein transferase activity;GO:0032550;GO:0019787//ubiquitin-like protein transferase activity;GO:0032550 GO:0035966//response to topologically incorrect protein;GO:0032446//protein modification by small protein conjugation;GO:0035966//response to topologically incorrect protein;GO:0032446//protein modification by small protein conjugation;GO:0035966//response to topologically incorrect protein;GO:0032446//protein modification by small protein conjugation;GO:0035966//response to topologically incorrect protein;GO:0032446//protein modification by small protein conjugation;GO:0035966//response to topologically incorrect protein;GO:0032446//protein modification by small protein conjugation;GO:0035966//response to topologically incorrect protein;GO:0032446//protein modification by small protein conjugation gi|537231821|gb|ERE84253.1|/1.21094e-151/ubiquitin-conjugating enzyme E2 J2-like isoform 1 [Cricetulus griseus] 629378 2828 9.12 10.14333333 0.153426104 Up 0.282475836 Dact3 dishevelled-binding antagonist of beta-catenin 3 K04263|1|3e-06|57.0|myb:102251650|prostacyclin receptor - - - - 21677 2041.33 4.91 4.273333333 -0.200361168 Down 0.282447629 Tead2 TEA domain family member 2 K09448|1|0.0|743|mmu:21677|transcriptional enhancer factor GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003676//nucleic acid binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003676//nucleic acid binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003676//nucleic acid binding" GO:0003007//heart morphogenesis;GO:0014020;GO:0048568//embryonic organ development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007498//mesoderm development;GO:0008219//cell death;GO:0035556//intracellular signal transduction;GO:0003007//heart morphogenesis;GO:0014020;GO:0048568//embryonic organ development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007498//mesoderm development;GO:0008219//cell death;GO:0035556//intracellular signal transduction;GO:0003007//heart morphogenesis;GO:0014020;GO:0048568//embryonic organ development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007498//mesoderm development;GO:0008219//cell death;GO:0035556//intracellular signal transduction gi|74201288|dbj|BAE26103.1|/0/unnamed protein product [Mus musculus] 22026 7637 3.146666667 3.69 0.229796457 Up 0.282391214 Nr2c2 "nuclear receptor subfamily 2, group C, member 2" K08544|1|0.0|1186|cfa:484641|testicular receptor 4 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0007610//behavior;GO:0009790//embryo development;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0022037//metencephalon development;GO:0007049//cell cycle gi|912822|gb|AAB33314.1|/0/type II zinc finger DNA binding transcription factor [Mus sp.] 380732 1319.08 0.866666667 1.193333333 0.461447964 Up 0.282353605 Milr1 mast cell immunoglobulin like receptor 1 - GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane - GO:0002695//negative regulation of leukocyte activation;GO:0002279;GO:0002695//negative regulation of leukocyte activation;GO:0002279;GO:0002695//negative regulation of leukocyte activation;GO:0002279;GO:0002695//negative regulation of leukocyte activation;GO:0002279;GO:0002695//negative regulation of leukocyte activation;GO:0002279;GO:0002695//negative regulation of leukocyte activation;GO:0002279 gi|406035332|ref|NP_001258302.1|/3.22311e-131/allergin-1 isoform c precursor [Mus musculus] 216810 4909.2 57.89666667 53.72333333 -0.107931468 Down 0.282353605 Tom1l2 target of myb1-like 2 (chicken) K12404|1|1e-22|112|mze:101485576|ADP-ribosylation factor-binding protein GGA - - GO:0015031//protein transport;GO:0015031//protein transport;GO:0015031//protein transport gi|625251457|ref|XP_007617046.1|/0/PREDICTED: TOM1-like protein 2 isoform X4 [Cricetulus griseus] 74122 2850 13.02 11.84 -0.137060368 Down 0.282212569 Tmem43 transmembrane protein 43 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|21311891|ref|NP_083042.1|/0/transmembrane protein 43 [Mus musculus] 208211 1772 11.61333333 12.79333333 0.139610088 Up 0.282212569 Alg1 "asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase)" "K03842|1|0.0|971|mmu:208211|beta-1,4-mannosyltransferase [EC:2.4.1.142]" GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0019187//beta-1,4-mannosyltransferase activity" GO:0006464//cellular protein modification process gi|148277043|ref|NP_663337.2|/0/chitobiosyldiphosphodolichol beta-mannosyltransferase [Mus musculus] 71037 1015 0.596666667 0.89 0.576880154 Up 0.282193764 Prss55 "protease, serine 55" K20111|1|1e-45|186|apla:101798316|oviductin [EC:3.4.21.120];K09640|3|3e-45|184|gga:428320|transmembrane protease serine 9 [EC:3.4.21.-] GO:0031224//intrinsic component of membrane GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|124486704|ref|NP_001074532.1|/5.8657e-180/serine protease 55 precursor [Mus musculus] 75659 1267 0.873333333 0.583333333 -0.58221189 Down 0.282193764 Wdr54 WD repeat domain 54 - - - - gi|12963827|ref|NP_076279.1|/0/WD repeat-containing protein 54 [Mus musculus] 22380 3452 5.51 6.25 0.181803871 Up 0.282184362 Wbp4 WW domain binding protein 4 K13220|1|2e-177|625|mmu:22380|WW domain-binding protein 4 GO:0016604//nuclear body;GO:0030529//intracellular ribonucleoprotein complex;GO:0016020//membrane GO:0046914//transition metal ion binding;GO:0005515//protein binding "GO:0000398//mRNA splicing, via spliceosome" gi|84871981|ref|NP_061235.2|/1.75018e-176/WW domain-binding protein 4 [Mus musculus] 230279 3630 5.666666667 6.406666667 0.17707359 Up 0.282184362 6330416G13Rik transmembrane protein 268 - GO:0031224//intrinsic component of membrane - - gi|27885007|ref|NP_659154.2|/7.05131e-176/transmembrane protein C9orf91 homolog [Mus musculus] 66176 1130 15.59333333 17.08333333 0.131660143 Up 0.282156155 Nat9 "N-acetyltransferase 9 (GCN5-related, putative)" K00327|1|2e-40|169|tsp:Tsp_02446|NADPH-ferrihemoprotein reductase [EC:1.6.2.4] GO:0032991//macromolecular complex GO:0016407//acetyltransferase activity - gi|13384782|ref|NP_079676.1|/2.50228e-137/N-acetyltransferase 9 [Mus musculus] 16790 3439 4.406666667 3.803333333 -0.212423385 Down 0.282090338 Anpep alanyl (membrane) aminopeptidase K11140|1|0.0|1865|mmu:16790|aminopeptidase N [EC:3.4.11.2] GO:0031988//membrane-bounded vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0033218//amide binding GO:0048869//cellular developmental process;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0019538//protein metabolic process;GO:0035813//regulation of renal sodium excretion;GO:0044237//cellular metabolic process gi|225637487|ref|NP_032512.2|/0/aminopeptidase N [Mus musculus] 23961 1848 1.726666667 2.143333333 0.31186664 Up 0.281977509 Oas1b 2'-5' oligoadenylate synthetase 1B K14216|1|0.0|759|mmu:23961|2'-5'-oligoadenylate synthetase [EC:2.7.7.84] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0032550;GO:0003723//RNA binding;GO:0003824//catalytic activity;GO:0032550;GO:0003723//RNA binding;GO:0003824//catalytic activity GO:0019079//viral genome replication;GO:0006952//defense response;GO:0051707//response to other organism;GO:0002252;GO:0019079//viral genome replication;GO:0006952//defense response;GO:0051707//response to other organism;GO:0002252 gi|145580613|ref|NP_001077394.1|/0/inactive 2'-5'-oligoadenylate synthase 1B [Mus musculus] 66069 1370 6.336666667 7.136666667 0.171526264 Up 0.281930498 Snupn snurportin 1 K13151|1|0.0|704|mmu:66069|snurportin-1 GO:0005635//nuclear envelope;GO:0034518//RNA cap binding complex GO:0003676//nucleic acid binding;GO:0022892//substrate-specific transporter activity GO:0006404//RNA import into nucleus;GO:0006886//intracellular protein transport gi|30410012|ref|NP_848461.1|/0/snurportin-1 [Mus musculus] 15251 4644.58 10.27 9.263333333 -0.148832848 Down 0.28190229 Hif1a "hypoxia inducible factor 1, alpha subunit" K08268|1|0.0|1496|mmu:15251|hypoxia-inducible factor 1 alpha - - - - 67824 1453 1.563333333 1.966666667 0.331127032 Up 0.281789462 Nmral1 NmrA-like family domain containing 1 K12757|1|2e-08|63.2|nle:100600508|myosin regulatory light chain 12 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - "gi|148664829|gb|EDK97245.1|/1.20585e-142/NmrA-like family domain containing 1, isoform CRA_b, partial [Mus musculus]" 217219 3099 1.943333333 1.543333333 -0.33248369 Down 0.281789462 Fam171a2 "family with sequence similarity 171, member A2" K06476|1|9e-41|171|fpg:101913845|integrin alpha 2B GO:0031224//intrinsic component of membrane - - gi|110347502|ref|NP_954670.2|/0/protein FAM171A2 precursor [Mus musculus] 71508 2439 1.526666667 1.166666667 -0.387992676 Down 0.281695438 Zfp935 zinc finger protein 935 K09228|1|0.0|815|mmu:105245687|KRAB domain-containing zinc finger protein - - - gi|755485546|ref|XP_011243468.1|/0/PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC105245687 [Mus musculus] 17967 5393.46 0.99 1.333333333 0.429537069 Up 0.281695438 Ncam1 neural cell adhesion molecule 1 K06491|1|0.0|1380|mmu:17967|neural cell adhesion molecule - - - gi|901694029|ref|NP_001297994.1|/0/neural cell adhesion molecule 1 isoform 4 precursor [Mus musculus] 20203 1676 0.32 0.566666667 0.824428435 Up 0.281676633 S100b "S100 protein, beta polypeptide, neural" K17274|1|2e-07|60.1|ola:101155699|calpactin-1 light chain GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0031252//cell leading edge;GO:0044421;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0008092//cytoskeletal protein binding;GO:0042802//identical protein binding GO:0015980//energy derivation by oxidation of organic compounds;GO:0022604//regulation of cell morphogenesis;GO:0007417//central nervous system development;GO:0007611//learning or memory;GO:0008283//cell proliferation;GO:0048168//regulation of neuronal synaptic plasticity;GO:0006915//apoptotic process;GO:0001817//regulation of cytokine production;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0035914//skeletal muscle cell differentiation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0001666//response to hypoxia;GO:0012502//induction of programmed cell death;GO:0031960//response to corticosteroid;GO:0006952//defense response;GO:0006875//cellular metal ion homeostasis gi|725595815|ref|XP_003939460.2|/1.41964e-35/PREDICTED: protein S100-B isoform X1 [Saimiri boliviensis boliviensis] 69574 1069 27.17666667 25.09333333 -0.115064387 Down 0.281629621 Cmbl carboxymethylenebutenolidase-like (Pseudomonas) K01061|1|3e-145|516|mmu:69574|carboxymethylenebutenolidase [EC:3.1.1.45] GO:0044424 GO:0003824//catalytic activity - gi|31712014|ref|NP_853619.1|/2.51141e-144/carboxymethylenebutenolidase homolog [Mus musculus] 13590 1622 0.206666667 0.423333333 1.034488376 Up 0.281563805 Lefty1 left right determination factor 1 K04668|1|0.0|653|mmu:13590|left-right determination factor GO:0044421 GO:0005126//cytokine receptor binding GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0001667//ameboidal-type cell migration;GO:0008283//cell proliferation;GO:0009855//determination of bilateral symmetry;GO:0032926//negative regulation of activin receptor signaling pathway;GO:0031333//negative regulation of protein complex assembly;GO:0009798//axis specification;GO:0009887//organ morphogenesis;GO:0033993//response to lipid gi|6753702|ref|NP_034224.1|/0/left-right determination factor 1 precursor [Mus musculus] 13202 609 48.73 52.67666667 0.112353833 Up 0.281469781 Ddt D-dopachrome tautomerase K10028|1|7e-61|235|mmu:13202|D-dopachrome decarboxylase [EC:4.1.1.84] GO:0044424 GO:0016831//carboxy-lyase activity GO:0006952//defense response;GO:0006582//melanin metabolic process gi|6753618|ref|NP_034157.1|/4.78217e-60/D-dopachrome decarboxylase [Mus musculus] 72185 1373.04 0.513333333 0.273333333 -0.909234536 Down 0.281422769 Dbndd1 dysbindin (dystrobrevin binding protein 1) domain containing 1 - GO:0044424 - - gi|339717166|ref|NP_001164447.2|/5.14612e-34/dysbindin domain-containing protein 1 isoform 3 [Mus musculus] 69639 1270 5.446666667 6.176666667 0.181454898 Up 0.281385159 Exosc8 exosome component 8 K12586|1|3e-157|556|mmu:69639|exosome complex component RRP43 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004527//exonuclease activity;GO:0003723//RNA binding;GO:0004527//exonuclease activity;GO:0003723//RNA binding GO:0042254//ribosome biogenesis;GO:0042254//ribosome biogenesis gi|60359866|dbj|BAD90152.1|/7.60696e-165/mKIAA4013 protein [Mus musculus] 634731 3295 0.446666667 0.72 0.688798312 Up 0.281375757 Susd1 sushi domain containing 1 K04595|1|2e-32|144|mze:101470640|latrophilin and seven transmembrane domain containing 1 - - - gi|261598994|ref|NP_001156760.2|/0/sushi domain-containing protein 1 precursor [Mus musculus] 268857 2003 0.7 0.433333333 -0.691877705 Down 0.281375757 Nlrc3 "NLR family, CARD domain containing 3" "K12800|1|8e-85|318|mze:101476350|NACHT, LRR and PYD domains-containing protein 3" GO:0044424 GO:0032550 GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0046649//lymphocyte activation gi|30425328|ref|NP_780756.1|/0/protein NLRC3 isoform 2 [Mus musculus] 56353 4376 3.32 2.813333333 -0.238902743 Down 0.281300538 Rybp RING1 and YY1 binding protein K11469|1|7e-66|255|bacu:103000335|RING1 and YY1-binding protein GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding GO:0010390//histone monoubiquitination;GO:0032502//developmental process gi|655835488|ref|XP_008259152.1|/6.20699e-65/PREDICTED: RING1 and YY1-binding protein [Oryctolagus cuniculus] 17936 5098 4.816666667 4.183333333 -0.203382129 Down 0.281215916 Nab1 Ngfi-A binding protein 1 - GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding "GO:0008366//axon ensheathment;GO:0008544//epidermis development;GO:0036075;GO:0007422//peripheral nervous system development;GO:0006351//transcription, DNA-templated" gi|31543307|ref|NP_032693.2|/0/NGFI-A-binding protein 1 [Mus musculus] 66642 2731 8.496666667 7.61 -0.159000514 Down 0.281187709 Ctnnbl1 "catenin, beta like 1" K12864|1|0.0|1057|mmu:66642|beta-catenin-like protein 1 GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0030529//intracellular ribonucleoprotein complex GO:0005515//protein binding GO:0012502//induction of programmed cell death;GO:0006396//RNA processing;GO:0006915//apoptotic process;GO:0002200 gi|254540032|ref|NP_079956.3|/0/beta-catenin-like protein 1 [Mus musculus] 232875 3626 0.33 0.58 0.813586876 Up 0.281168904 Zscan18 zinc finger and SCAN domain containing 18 K09230|1|5e-127|458|ocu:100353219|SCAN domain-containing zinc finger protein - - - gi|755519384|ref|XP_011248809.1|/0/PREDICTED: zinc finger and SCAN domain-containing protein 18 isoform X2 [Mus musculus] 319415 3063 0.33 0.58 0.813586876 Up 0.281168904 Hs3st5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 K08104|1|0.0|669|mmu:319415|[heparan sulfate]-glucosamine 3-sulfotransferase 5 [EC:2.8.2.23] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0034483//heparan sulfate sulfotransferase activity;GO:0034483//heparan sulfate sulfotransferase activity;GO:0034483//heparan sulfate sulfotransferase activity GO:0046718//viral entry into host cell;GO:0050817//coagulation;GO:0006464//cellular protein modification process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0046718//viral entry into host cell;GO:0050817//coagulation;GO:0006464//cellular protein modification process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0046718//viral entry into host cell;GO:0050817//coagulation;GO:0006464//cellular protein modification process;GO:0015012//heparan sulfate proteoglycan biosynthetic process gi|124487077|ref|NP_001074677.1|/0/heparan sulfate glucosamine 3-O-sulfotransferase 5 [Mus musculus] 66999 4568 4.723333333 5.393333333 0.19137185 Up 0.281159502 Med28 mediator complex subunit 28 K15141|1|2e-83|313|mmu:66999|mediator of RNA polymerase II transcription subunit 28 - - - - 327951 794 5.52 4.853333333 -0.185692317 Down 0.281159502 Cyb5d1 cytochrome b5 domain containing 1 K11448|1|2e-74|280|cmy:102947171|lysine-specific demethylase 6B [EC:1.14.11.-] - - - - 18854 5318 5.436666667 4.766666667 -0.189741635 Down 0.281159502 Pml promyelocytic leukemia K10054|1|0.0|1693|mmu:18854|probable transcription factor PML GO:0034399//nuclear periphery;GO:0016604//nuclear body;GO:0005635//nuclear envelope;GO:0005789//endoplasmic reticulum membrane;GO:0034399//nuclear periphery;GO:0016604//nuclear body;GO:0005635//nuclear envelope;GO:0005789//endoplasmic reticulum membrane GO:0003712//transcription cofactor activity;GO:0042802//identical protein binding;GO:0003676//nucleic acid binding;GO:0032182//ubiquitin-like protein binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0003712//transcription cofactor activity;GO:0042802//identical protein binding;GO:0003676//nucleic acid binding;GO:0032182//ubiquitin-like protein binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0044389//ubiquitin-like protein ligase binding "GO:0050691//regulation of defense response to virus by host;GO:0030097//hemopoiesis;GO:0070670//response to interleukin-4;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0048754//branching morphogenesis of an epithelial tube;GO:0032055//negative regulation of translation in response to stress;GO:0030575//nuclear body organization;GO:0022402//cell cycle process;GO:0016049//cell growth;GO:0006351//transcription, DNA-templated;GO:0007004//telomere maintenance via telomerase;GO:0007569//cell aging;GO:0006874//cellular calcium ion homeostasis;GO:0009416//response to light stimulus;GO:0031397//negative regulation of protein ubiquitination;GO:0012502//induction of programmed cell death;GO:0097191//extrinsic apoptotic signaling pathway;GO:0016575//histone deacetylation;GO:0010212//response to ionizing radiation;GO:0006606//protein import into nucleus;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0030522//intracellular receptor signaling pathway;GO:0000278//mitotic cell cycle;GO:0030154//cell differentiation;GO:0051348//negative regulation of transferase activity;GO:0006282//regulation of DNA repair;GO:0008283//cell proliferation;GO:0032386//regulation of intracellular transport;GO:0001525//angiogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0065003;GO:0031647//regulation of protein stability;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006468//protein phosphorylation;GO:0050691//regulation of defense response to virus by host;GO:0030097//hemopoiesis;GO:0070670//response to interleukin-4;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0048754//branching morphogenesis of an epithelial tube;GO:0032055//negative regulation of translation in response to stress;GO:0030575//nuclear body organization;GO:0022402//cell cycle process;GO:0016049//cell growth;GO:0006351//transcription, DNA-templated;GO:0007004//telomere maintenance via telomerase;GO:0007569//cell aging;GO:0006874//cellular calcium ion homeostasis;GO:0009416//response to light stimulus;GO:0031397//negative regulation of protein ubiquitination;GO:0012502//induction of programmed cell death;GO:0097191//extrinsic apoptotic signaling pathway;GO:0016575//histone deacetylation;GO:0010212//response to ionizing radiation;GO:0006606//protein import into nucleus;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0030522//intracellular receptor signaling pathway;GO:0000278//mitotic cell cycle;GO:0030154//cell differentiation;GO:0051348//negative regulation of transferase activity;GO:0006282//regulation of DNA repair;GO:0008283//cell proliferation;GO:0032386//regulation of intracellular transport;GO:0001525//angiogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0065003;GO:0031647//regulation of protein stability;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006468//protein phosphorylation" gi|568960843|ref|XP_006510923.1|/0/PREDICTED: protein PML isoform X1 [Mus musculus] 27632 1424.6 9.253333333 10.25666667 0.148516876 Up 0.281159502 Nelfe "negative elongation factor complex member E, Rdbp" K15182|1|4e-139|497|mmu:27632|negative elongation factor E GO:0008023//transcription elongation factor complex;GO:0008023//transcription elongation factor complex;GO:0008023//transcription elongation factor complex GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0044764;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0044764;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0044764;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process "gi|148694798|gb|EDL26745.1|/3.49766e-138/RD RNA-binding protein, isoform CRA_a [Mus musculus]" 66705 1236 0.163333333 0.373333333 1.192645078 Up 0.28111249 Dnase1l2 deoxyribonuclease 1-like 2 K11995|1|5e-161|569|mmu:66705|deoxyribonuclease-1-like protein [EC:3.1.21.-] - GO:0004520//endodeoxyribonuclease activity GO:0006259//DNA metabolic process "gi|148690371|gb|EDL22318.1|/8.93566e-164/deoxyribonuclease 1-like 2, isoform CRA_a [Mus musculus]" 237222 4453 1.273333333 1.643333333 0.368015008 Up 0.281074881 Ofd1 oral-facial-digital syndrome 1 gene homolog (human) K16480|1|0.0|1690|mmu:237222|oral-facial-digital syndrome 1 protein GO:0043231//intracellular membrane-bounded organelle;GO:0005813//centrosome GO:0015631//tubulin binding GO:0048858//cell projection morphogenesis;GO:0000087//mitotic M phase;GO:0007052//mitotic spindle organization;GO:0003351//epithelial cilium movement gi|225007605|ref|NP_803178.2|/0/oral-facial-digital syndrome 1 protein homolog [Mus musculus] 70008 3418 0.97 0.666666667 -0.541019153 Down 0.281009064 Ace2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 K09708|1|0.0|1488|mmu:70008|angiotensin-converting enzyme 2 [EC:3.4.17.23] GO:0031224//intrinsic component of membrane;GO:0044464;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0044421 GO:0042277//peptide binding;GO:0043169//cation binding;GO:0008238//exopeptidase activity;GO:0004872//receptor activity;GO:0005515//protein binding;GO:0042277//peptide binding;GO:0043169//cation binding;GO:0008238//exopeptidase activity;GO:0004872//receptor activity;GO:0005515//protein binding GO:0051707//response to other organism;GO:0002035//brain renin-angiotensin system;GO:0019062//virion attachment to host cell;GO:0019538//protein metabolic process;GO:0009059//macromolecule biosynthetic process;GO:0042311//vasodilation;GO:0051707//response to other organism;GO:0002035//brain renin-angiotensin system;GO:0019062//virion attachment to host cell;GO:0019538//protein metabolic process;GO:0009059//macromolecule biosynthetic process;GO:0042311//vasodilation gi|83582782|ref|NP_081562.2|/0/angiotensin-converting enzyme 2 precursor [Mus musculus] 100201 4681 7.02 6.233333333 -0.171467166 Down 0.28095265 Tmem64 transmembrane protein 64 K18411|1|7e-27|126|bmor:101744192|protein maelstrom;K02146|3|7e-11|73.2|isc:IscW_ISCW002101|V-type H+-transporting ATPase subunit d - - - gi|225543079|ref|NP_852066.2|/1.00771e-137/transmembrane protein 64 [Mus musculus] 108900 1376 0.513333333 0.793333333 0.628031223 Up 0.280858626 Fam72a "family with sequence similarity 72, member A" - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - GO:0006915//apoptotic process;GO:0031549//negative regulation of brain-derived neurotrophic factor receptor signaling pathway gi|77415489|gb|AAI06124.1|/2.52007e-76/RIKEN cDNA 2700049P18 gene [Mus musculus] 18019 5625.65 3.64 3.113333333 -0.225478401 Down 0.280811614 Nfatc2 "nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2" "K17332|1|6e-130|467|mmu:18019|nuclear factor of activated T-cells, cytoplasmic 2" GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0033554//cellular response to stress "gi|209862955|ref|NP_001129545.1|/0/nuclear factor of activated T-cells, cytoplasmic 2 isoform d [Mus musculus]" 66680 1583 11.67666667 12.82333333 0.135142841 Up 0.280802211 Oser1 oxidative stress responsive serine rich 1 - - - - "gi|148674377|gb|EDL06324.1|/0/RIKEN cDNA 3230401D17, isoform CRA_a, partial [Mus musculus]" 76784 2987.95 12.69666667 11.55 -0.136556936 Down 0.280802211 Mtif2 mitochondrial translational initiation factor 2 K02519|1|0.0|1383|mmu:76784|translation initiation factor IF-2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0017111//nucleoside-triphosphatase activity;GO:0003723//RNA binding;GO:0032550;GO:0043021//ribonucleoprotein complex binding;GO:0017111//nucleoside-triphosphatase activity;GO:0003723//RNA binding;GO:0032550;GO:0043021//ribonucleoprotein complex binding;GO:0017111//nucleoside-triphosphatase activity;GO:0003723//RNA binding;GO:0032550;GO:0043021//ribonucleoprotein complex binding;GO:0017111//nucleoside-triphosphatase activity;GO:0003723//RNA binding;GO:0032550;GO:0043021//ribonucleoprotein complex binding GO:0006413//translational initiation;GO:0006413//translational initiation;GO:0006413//translational initiation;GO:0006413//translational initiation "gi|530788299|ref|NP_001269048.1|/0/translation initiation factor IF-2, mitochondrial isoform 2 [Mus musculus]" 76773 1409 9.06 10.05333333 0.150090973 Up 0.280661176 Wdyhv1 WDYHV motif containing 1 K01866|1|1e-24|117|loa:LOAG_04233|tyrosyl-tRNA synthetase [EC:6.1.1.1] - - - - 234796 2156 1.916666667 2.346666667 0.292013473 Up 0.280548347 Klhl36 kelch-like 36 K13958|1|0.0|1225|mmu:234796|kelch-like protein 36 - - - gi|47847426|dbj|BAD21385.1|/0/mFLJ00127 protein [Mus musculus] 19290 1602 7.55 8.433333333 0.159626335 Up 0.280538945 Pura purine rich element binding protein A K11838|1|7e-92|340|chx:102188997|ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12];K10356|3|2e-25|119|myd:102759127|myosin I;K13696|5|6e-08|61.6|hro:HELRODRAFT_182167|abhydrolase domain-containing protein 1/3 "GO:0000781//chromosome, telomeric region;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043234//protein complex" "GO:0005515//protein binding;GO:0030371//translation repressor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003690//double-stranded DNA binding" "GO:0048731//system development;GO:0006351//transcription, DNA-templated;GO:0006261//DNA-dependent DNA replication;GO:0008283//cell proliferation" gi|982252987|ref|XP_015306971.1|/1.27774e-130/PREDICTED: transcriptional activator protein Pur-alpha [Macaca fascicularis] 74114 2803 8.653333333 7.77 -0.155341379 Down 0.280538945 Crot carnitine O-octanoyltransferase K05940|1|0.0|1266|mmu:74114|carnitine O-octanoyltransferase [EC:2.3.1.137] GO:0042579//microbody GO:0005515//protein binding;GO:0016406//carnitine O-acyltransferase activity GO:0015908//fatty acid transport;GO:0009719;GO:0009062//fatty acid catabolic process;GO:0042221//response to chemical gi|17157983|ref|NP_076222.1|/0/peroxisomal carnitine O-octanoyltransferase [Mus musculus] 105245 2671 24.33666667 22.32333333 -0.124579112 Down 0.28052014 Txndc5 thioredoxin domain containing 5 K13984|1|0.0|681|mmu:105245|thioredoxin domain-containing protein 5 GO:0005764//lysosome;GO:0044432;GO:0044432;GO:0044432 GO:0015036//disulfide oxidoreductase activity;GO:0015036//disulfide oxidoreductase activity;GO:0015036//disulfide oxidoreductase activity GO:0006915//apoptotic process;GO:0019725//cellular homeostasis;GO:0018904;GO:0048193//Golgi vesicle transport;GO:0019725//cellular homeostasis;GO:0018904;GO:0019725//cellular homeostasis;GO:0018904 gi|148708993|gb|EDL40939.1|/0/thioredoxin domain containing 5 [Mus musculus] 67665 3714 16.55666667 15.12333333 -0.130636087 Down 0.280510738 Dctn4 dynactin 4 K10426|1|0.0|897|mmu:67665|dynactin 4 GO:0005815//microtubule organizing center;GO:0030286//dynein complex;GO:0044444//cytoplasmic part GO:0005515//protein binding - gi|13385798|ref|NP_080578.1|/0/dynactin subunit 4 [Mus musculus] 231630 3192 5.34 6.06 0.182478052 Up 0.28028508 Ficd FIC domain containing K17277|1|2e-95|353|tsp:Tsp_04127|epidermal growth factor receptor kinase substrate 8 GO:0031224//intrinsic component of membrane GO:0070566//adenylyltransferase activity;GO:0032550 GO:0018175 gi|169646312|ref|NP_001010825.2|/0/adenosine monophosphate-protein transferase FICD [Mus musculus] 68134 2367 2.196666667 1.78 -0.303438723 Down 0.280059423 Upf3b UPF3 regulator of nonsense transcripts homolog B (yeast) K14328|1|7e-173|610|mmu:68134|regulator of nonsense transcripts 3 - - - - 20616 3874.3 2.073333333 2.516666667 0.279562064 Up 0.280050021 Snap91 synaptosomal-associated protein 91 K20043|1|0.0|1154|mmu:20616|clathrin coat assembly protein AP180 GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0030128//clathrin coat of endocytic vesicle;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0030128//clathrin coat of endocytic vesicle;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0030128//clathrin coat of endocytic vesicle;GO:0097458//neuron part;GO:0097060//synaptic membrane;GO:0030128//clathrin coat of endocytic vesicle;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0030128//clathrin coat of endocytic vesicle GO:0035091//phosphatidylinositol binding;GO:0030276//clathrin binding;GO:0035091//phosphatidylinositol binding;GO:0030276//clathrin binding;GO:0035091//phosphatidylinositol binding;GO:0030276//clathrin binding;GO:0035091//phosphatidylinositol binding;GO:0030276//clathrin binding;GO:0005488//binding;GO:0035091//phosphatidylinositol binding;GO:0030276//clathrin binding GO:0006901//vesicle coating;GO:0015031//protein transport;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006897//endocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006901//vesicle coating;GO:0015031//protein transport;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006897//endocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006901//vesicle coating;GO:0015031//protein transport;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006897//endocytosis;GO:0001505//regulation of neurotransmitter levels;GO:0006901//vesicle coating;GO:0001505//regulation of neurotransmitter levels;GO:0006901//vesicle coating;GO:0015031//protein transport;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006897//endocytosis;GO:0001505//regulation of neurotransmitter levels gi|7305507|ref|NP_038697.1|/0/clathrin coat assembly protein AP180 isoform 1 [Mus musculus] 321000 2317.73 2.083333333 2.523333333 0.27643711 Up 0.280050021 Lrif1 ligand dependent nuclear receptor interacting factor 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0008134//transcription factor binding;GO:0008134//transcription factor binding;GO:0008134//transcription factor binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|87162474|ref|NP_001034577.1|/4.34434e-112/ligand-dependent nuclear receptor-interacting factor 1 isoform 1 [Mus musculus] 76457 2070.58 2.003333333 2.44 0.284478658 Up 0.280050021 Ccdc134 coiled-coil domain containing 134 K10802|1|2e-12|69.7|aqu:100632949|high mobility group protein B1 - - - gi|116268089|ref|NP_766016.2|/6.17568e-107/coiled-coil domain-containing protein 134 precursor [Mus musculus] 79565 2831 0.516666667 0.796666667 0.624742403 Up 0.280040618 Wbscr27 Williams Beuren syndrome chromosome region 27 (human) - - - - "gi|148687462|gb|EDL19409.1|/3.57903e-156/Williams Beuren syndrome chromosome region 27 (human), isoform CRA_c, partial [Mus musculus]" 75996 952 0.68 0.983333333 0.532145802 Up 0.279984204 5033428I22Rik RIKEN cDNA 5033428I22 gene - - - - - 12234 6358 4.246666667 4.863333333 0.195614606 Up 0.279918387 Btrc beta-transducin repeat containing protein K03362|1|0.0|1157|bta:534072|F-box and WD-40 domain protein 1/11 GO:0043231//intracellular membrane-bounded organelle;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0031461//cullin-RING ubiquitin ligase complex GO:0051219//phosphoprotein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0051219//phosphoprotein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0051219//phosphoprotein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0051219//phosphoprotein binding;GO:0019787//ubiquitin-like protein transferase activity "GO:0006351//transcription, DNA-templated;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031647//regulation of protein stability;GO:0050673//epithelial cell proliferation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0044092//negative regulation of molecular function;GO:0014070//response to organic cyclic compound;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007224//smoothened signaling pathway;GO:0048754//branching morphogenesis of an epithelial tube;GO:0007623//circadian rhythm;GO:0006351//transcription, DNA-templated;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031647//regulation of protein stability;GO:0050673//epithelial cell proliferation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0044092//negative regulation of molecular function;GO:0014070//response to organic cyclic compound;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007224//smoothened signaling pathway;GO:0048754//branching morphogenesis of an epithelial tube;GO:0007623//circadian rhythm;GO:0006351//transcription, DNA-templated;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031647//regulation of protein stability;GO:0050673//epithelial cell proliferation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0044092//negative regulation of molecular function;GO:0014070//response to organic cyclic compound;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007224//smoothened signaling pathway;GO:0048754//branching morphogenesis of an epithelial tube;GO:0007623//circadian rhythm;GO:0006351//transcription, DNA-templated;GO:0007166//cell surface receptor signaling pathway;GO:0031647//regulation of protein stability;GO:0050673//epithelial cell proliferation;GO:0010498//proteasomal protein catabolic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0014070//response to organic cyclic compound;GO:0032446//protein modification by small protein conjugation;GO:0048754//branching morphogenesis of an epithelial tube;GO:0019941//modification-dependent protein catabolic process;GO:0007049//cell cycle;GO:0007623//circadian rhythm" "gi|148710006|gb|EDL41952.1|/0/beta-transducin repeat containing protein, isoform CRA_b, partial [Mus musculus]" 26466 3851 4.703333333 4.086666667 -0.202759009 Down 0.279918387 Zfp260 zinc finger protein 260 K09228|1|0.0|734|bom:102284102|KRAB domain-containing zinc finger protein GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|31544063|ref|NP_036111.2|/0/zinc finger protein 260 [Mus musculus] 94221 4319 4.693333333 4.076666667 -0.20322293 Down 0.279918387 Gopc golgi associated PDZ and coiled-coil motif containing K19931|1|3e-12|77.4|phu:Phum_PHUM022290|protein lin-7 GO:0032991//macromolecular complex;GO:0097060//synaptic membrane;GO:0005798//Golgi-associated vesicle;GO:0032991//macromolecular complex;GO:0097060//synaptic membrane;GO:0005798//Golgi-associated vesicle GO:0042802//identical protein binding;GO:0001664//G-protein coupled receptor binding;GO:0030695//GTPase regulator activity;GO:0042802//identical protein binding;GO:0001664//G-protein coupled receptor binding GO:0044248;GO:0051259//protein oligomerization;GO:0019222//regulation of metabolic process;GO:0045184//establishment of protein localization;GO:0006997//nucleus organization;GO:0044248;GO:0051259//protein oligomerization;GO:0019222//regulation of metabolic process;GO:0045184//establishment of protein localization;GO:0006997//nucleus organization gi|313151170|ref|NP_001186201.1|/0/Golgi-associated PDZ and coiled-coil motif-containing protein isoform a [Mus musculus] 12715 1415 1921.1 2059.836667 0.100597326 Up 0.27989018 Ckm "creatine kinase, muscle" K00933|1|0.0|729|mmu:12715|creatine kinase [EC:2.7.3.2] GO:0044424 GO:0016301//kinase activity;GO:0032550 GO:0006603//phosphocreatine metabolic process gi|6671762|ref|NP_031736.1|/0/creatine kinase M-type [Mus musculus] 271221 2651 1.456666667 1.103333333 -0.400802063 Down 0.279880778 5031414D18Rik RIKEN cDNA 5031414D18 gene K19330|1|3e-72|276|ccw:104687942|run domain Beclin-1 interacting and cysteine-rich containing protein - - - gi|156151398|ref|NP_941044.3|/0/uncharacterized protein KIAA0226-like [Mus musculus] 71041 2091 1.086666667 1.433333333 0.399464695 Up 0.279880778 Pcgf6 polycomb group ring finger 6 K11470|1|1e-140|350|mmu:71041|polycomb group RING finger protein 6 - - - - 103511 1786 1.45 1.096666667 -0.402927817 Down 0.279880778 Fam26e "family with sequence similarity 26, member E" K19739|1|8e-28|127|oaa:100081241|calcium homeostasis modulator protein 2 GO:0031224//intrinsic component of membrane - - gi|26351867|dbj|BAC39570.1|/0/unnamed protein product [Mus musculus] 100043160 372 1555.62 1666.986667 0.099752877 Up 0.279796156 Gm10012 "cytochrome c oxidase, subunit VIIc pseudogene" K02272|1|1e-29|129|mmu:12867|cytochrome c oxidase subunit 7c GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0015002//heme-copper terminal oxidase activity GO:0006818//hydrogen transport;GO:0006811//ion transport;GO:0044710 gi|148690527|gb|EDL22474.1|/4.75358e-29/mCG17670 [Mus musculus] 12215 1404.93 1318.233333 1408.223333 0.095270396 Up 0.27973034 Bsg basigin K06535|1|4e-142|507|mmu:12215|basigin GO:0031224//intrinsic component of membrane;GO:0001669//acrosomal vesicle;GO:0012505//endomembrane system;GO:0048770;GO:0005886//plasma membrane;GO:0031224//intrinsic component of membrane;GO:0001669//acrosomal vesicle;GO:0048770;GO:0005886//plasma membrane GO:0048029//monosaccharide binding;GO:0048029//monosaccharide binding GO:0042476//odontogenesis;GO:0010038//response to metal ion;GO:0009725//response to hormone;GO:0046683//response to organophosphorus;GO:0032787//monocarboxylic acid metabolic process;GO:0001893//maternal placenta development;GO:0002376//immune system process;GO:0007599//hemostasis;GO:0007165//signal transduction;GO:0042476//odontogenesis;GO:0010038//response to metal ion;GO:0009725//response to hormone;GO:0046683//response to organophosphorus;GO:0001893//maternal placenta development gi|116014342|ref|NP_001070652.1|/1.3851e-146/basigin isoform 2 precursor [Mus musculus] 243755 3426 0.13 0.333333333 1.358453971 Up 0.279711535 Slc13a4 "solute carrier family 13 (sodium/sulfate symporters), member 4" "K14444|1|0.0|1016|mmu:243755|solute carrier family 13 (sodium/sulfate cotransporter), member 1/4" - - GO:0030001//metal ion transport;GO:0044763 gi|27370364|ref|NP_766480.1|/0/solute carrier family 13 member 4 [Mus musculus] 67379 1828 14.70333333 16.1 0.130917429 Up 0.279579901 Dedd2 death effector domain-containing DNA binding protein 2 - GO:0031981//nuclear lumen - GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0097191//extrinsic apoptotic signaling pathway gi|115299736|ref|NP_997560.3|/2.06164e-119/DNA-binding death effector domain-containing protein 2 [Mus musculus] 67453 4371 14.41333333 15.81 0.133433345 Up 0.279579901 Slc25a46 "solute carrier family 25, member 46" "K03454|1|0.0|800|mmu:67453|solute carrier family 25, member 46" GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0051234//establishment of localization gi|18044870|gb|AAH20087.1|/0/Slc25a46 protein [Mus musculus] 11717 3979 22.27 24.22 0.121097307 Up 0.279570499 Ampd3 adenosine monophosphate deaminase 3 K01490|1|0.0|1508|mmu:11717|AMP deaminase [EC:3.5.4.6] - - - - 14659 1957 0.126666667 0.323333333 1.351985329 Up 0.279561097 Glrp1 glutamine repeat protein 1 - - - - gi|119709818|ref|NP_032158.2|/4.66934e-08/glutamine repeat protein 1 [Mus musculus] 13609 3029 44.56333333 48.12333333 0.110879426 Up 0.279514085 S1pr1 sphingosine-1-phosphate receptor 1 K04288|1|0.0|726|mmu:13609|sphingosine 1-phosphate receptor 1 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0008289//lipid binding;GO:0045125//bioactive lipid receptor activity GO:0003158//endothelium development;GO:0050918//positive chemotaxis;GO:0008284//positive regulation of cell proliferation;GO:0032232//negative regulation of actin filament bundle assembly;GO:0016477//cell migration;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0030154//cell differentiation;GO:0007417//central nervous system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007155//cell adhesion;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway gi|21687214|ref|NP_031927.2|/0/sphingosine 1-phosphate receptor 1 [Mus musculus] 66966 2059 3.056666667 2.573333333 -0.248320886 Down 0.279467073 Trit1 tRNA isopentenyltransferase 1 K00791|1|0.0|865|mmu:66966|tRNA dimethylallyltransferase [EC:2.5.1.75] GO:0043231//intracellular membrane-bounded organelle "GO:0043169//cation binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0032550" GO:0006399//tRNA metabolic process "gi|27229019|ref|NP_080149.2|/0/tRNA dimethylallyltransferase, mitochondrial precursor [Mus musculus]" 27061 1295.33 46.22333333 49.75333333 0.106171884 Up 0.279429463 Bcap31 B cell receptor associated protein 31 K14009|1|1e-94|348|mmu:27061|B-cell receptor-associated protein 31 - - - - 73218 2887 8.753333333 9.72 0.151123803 Up 0.279391854 Sppl2b signal peptide peptidase like 2B K09597|1|0.0|1050|mmu:73218|signal peptide peptidase-like 2B [EC:3.4.23.-] GO:0005764//lysosome;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0000139//Golgi membrane GO:0042802//identical protein binding;GO:0004190//aspartic-type endopeptidase activity GO:0002682//regulation of immune system process;GO:0033619//membrane protein proteolysis gi|116805338|ref|NP_780404.2|/0/signal peptide peptidase-like 2B precursor [Mus musculus] 12005 3684.88 8.6 9.57 0.154182265 Up 0.279391854 Axin1 axin 1 K02157|1|0.0|1477|mmu:12005|axin 1 - - - gi|2252816|gb|AAC53285.1|/0/Axin [Mus musculus] 66513 3013 9.013333333 9.983333333 0.147460851 Up 0.279391854 Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 K04403|1|0.0|932|mmu:66513|TAK1-binding protein 1 GO:0032991//macromolecular complex;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0051019//mitogen-activated protein kinase binding;GO:0008047//enzyme activator activity" GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0002753;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032147//activation of protein kinase activity;GO:0043009//chordate embryonic development;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0030323//respiratory tube development;GO:0043405//regulation of MAP kinase activity;GO:0009887//organ morphogenesis;GO:0051403//stress-activated MAPK cascade gi|34328268|ref|NP_079885.2|/0/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [Mus musculus] 68525 4111 2.783333333 2.323333333 -0.260617541 Down 0.279382451 Evc2 Ellis van Creveld syndrome 2 K19608|1|0.0|2047|mmu:68525|ellis van creveld syndrome protein 2 GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0007166//cell surface receptor signaling pathway gi|22122329|ref|NP_666032.1|/0/limbin precursor [Mus musculus] 280645 4367 2.796666667 2.336666667 -0.259256366 Down 0.279382451 B3gat2 "beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)" K10157|1|0.0|663|mmu:280645|galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 [EC:2.4.1.135] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system GO:0015020//glucuronosyltransferase activity;GO:0043169//cation binding GO:0006022;GO:0044710;GO:0006790//sulfur compound metabolic process;GO:0006464//cellular protein modification process;GO:0044723 gi|60360092|dbj|BAD90265.1|/0/mKIAA1963 protein [Mus musculus] 16956 4049 928.4233333 867.5266667 -0.097874676 Down 0.279373049 Lpl lipoprotein lipase K01059|1|0.0|894|mmu:16956|lipoprotein lipase [EC:3.1.1.34] GO:0031224//intrinsic component of membrane;GO:0034385;GO:0044464 GO:0016298//lipase activity;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding GO:0006631//fatty acid metabolic process;GO:0006641//triglyceride metabolic process;GO:0034370//triglyceride-rich lipoprotein particle remodeling;GO:0055090//acylglycerol homeostasis;GO:0042221//response to chemical;GO:0010884//positive regulation of lipid storage;GO:0010742//macrophage derived foam cell differentiation;GO:0006950//response to stress;GO:0010878//cholesterol storage gi|74142467|dbj|BAE31986.1|/0/unnamed protein product [Mus musculus] 68876 1057.41 2.79 3.293333333 0.239283419 Up 0.279326037 Xrcc6bp1 XRCC6 binding protein 1 K18156|1|2e-105|384|mmu:68876|mitochondrial inner membrane protease ATP23 [EC:3.4.24.-] - GO:0004175//endopeptidase activity;GO:0043169//cation binding;GO:0004175//endopeptidase activity;GO:0043169//cation binding GO:0019538//protein metabolic process;GO:0019538//protein metabolic process gi|27754038|ref|NP_081134.2|/1.58679e-104/mitochondrial inner membrane protease ATP23 homolog isoform 2 [Mus musculus] 66970 6644.66 6.206666667 6.976666667 0.168719239 Up 0.279269623 Ssbp2 single-stranded DNA binding protein 2 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043566//structure-specific DNA binding;GO:0043566//structure-specific DNA binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|859969473|ref|XP_012906428.1|/1.88609e-137/PREDICTED: single-stranded DNA-binding protein 2-like isoform X2 [Mustela putorius furo] 16855 1465 42.15333333 45.64666667 0.114862793 Up 0.27926022 Lgals4 "lectin, galactose binding, soluble 4" K10091|1|0.0|652|mmu:16855|galectin-4 - GO:0005488//binding - gi|46849705|ref|NP_034836.1|/0/galectin-4 [Mus musculus] 78405 2027 0.13 0.326666667 1.329307625 Up 0.279250818 Ntf5 neurotrophin 5 K12457|1|5e-85|318|mmu:78405|neurotrophin 4 GO:0044432 GO:0005165//neurotrophin receptor binding GO:0009888//tissue development;GO:0001709//cell fate determination;GO:0007613//memory;GO:0050804//modulation of synaptic transmission;GO:0007423//sensory organ development;GO:0007626//locomotory behavior;GO:0030182//neuron differentiation "gi|148690904|gb|EDL22851.1|/6.62645e-106/neurotrophin 5, isoform CRA_a, partial [Mus musculus]" 14708 3362 0.73 0.463333333 -0.655845987 Down 0.279232013 Gng7 "guanine nucleotide binding protein (G protein), gamma 7" K04543|1|1e-29|135|mmu:14708|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 - - - gi|84579915|ref|NP_001033744.1|/9.12416e-29/guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [Mus musculus] 73230 3806 1.096666667 0.783333333 -0.485426827 Down 0.279166197 Bmper BMP-binding endothelial regulator K18273|1|2e-48|197|xtr:100490936|alpha-tectorin;K03900|5|3e-47|193|tru:101063204|von Willebrand factor GO:0044421 GO:0005488//binding GO:0043583//ear development;GO:0001935//endothelial cell proliferation;GO:0030334//regulation of cell migration;GO:0001932//regulation of protein phosphorylation;GO:0035295//tube development;GO:0001775//cell activation;GO:0043410//positive regulation of MAPK cascade;GO:0030509//BMP signaling pathway gi|24371216|ref|NP_082748.1|/0/BMP-binding endothelial regulator protein precursor [Mus musculus] 104831 5384 12.05666667 10.93666667 -0.140658004 Down 0.27910038 Ptpn23 "protein tyrosine phosphatase, non-receptor type 23" K18040|1|0.0|2660|mmu:104831|tyrosine-protein phosphatase non-receptor type 23 [EC:3.1.3.48] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0048858//cell projection morphogenesis gi|124517678|ref|NP_001074512.1|/0/tyrosine-protein phosphatase non-receptor type 23 [Mus musculus] 71435 6963.84 8.106666667 7.243333333 -0.162455054 Down 0.27910038 Arhgap21 Rho GTPase activating protein 21 K20315|1|0.0|3524|mmu:71435|Rho GTPase-activating protein 21/23 GO:0031982//vesicle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0008047//enzyme activator activity;GO:0008289//lipid binding GO:0010970//transport along microtubule;GO:0051645//Golgi localization;GO:0006996//organelle organization;GO:0007154//cell communication;GO:0010970//transport along microtubule;GO:0051645//Golgi localization;GO:0006996//organelle organization;GO:0007154//cell communication gi|203097667|ref|NP_001074833.3|/0/rho GTPase-activating protein 21 isoform 2 [Mus musculus] 13627 1790 650.1766667 696.05 0.098359162 Up 0.279015758 Eef1a1 eukaryotic translation elongation factor 1 alpha 1 K03231|1|0.0|961|oas:105613550|elongation factor 1-alpha GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008135//translation factor activity, RNA binding;GO:0019900//kinase binding" "GO:0006351//transcription, DNA-templated;GO:0006412//translation;GO:0006915//apoptotic process;GO:0009154//purine ribonucleotide catabolic process" gi|803119291|ref|XP_012040812.1|/0/PREDICTED: elongation factor 1-alpha 1-like isoform X1 [Ovis aries] 70719 3880.05 3.626666667 4.203333333 0.212889719 Up 0.279015758 Hmha1 histocompatibility (minor) HA-1 "K02649|1|9e-27|125|bfo:BRAFLDRAFT_91712|phosphoinositide-3-kinase, regulatory subunit;K10360|2|8e-25|119|hmg:100213152|myosin IX" GO:0044464;GO:0044464 GO:0008047//enzyme activator activity;GO:0043169//cation binding;GO:0008047//enzyme activator activity;GO:0043169//cation binding GO:0007165//signal transduction;GO:0007165//signal transduction gi|218156343|ref|NP_001136173.1|/0/minor histocompatibility protein HA-1 isoform 1 [Mus musculus] 381126 4783 3.45 2.933333333 -0.234055339 Down 0.278968746 Garem "GRB2 associated, regulator of MAPK1" K03006|1|4e-08|63.9|rro:104669448|DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] - GO:0005515//protein binding GO:0070849//response to epidermal growth factor;GO:0008283//cell proliferation;GO:0043410//positive regulation of MAPK cascade;GO:0038127//ERBB signaling pathway gi|134288888|ref|NP_001028617.2|/0/GRB2-associated and regulator of MAPK protein [Mus musculus] 93734 3223.61 1.193333333 0.87 -0.455909781 Down 0.278959344 Mpv17l "Mpv17 transgene, kidney disease mutant-like" K13349|1|2e-108|396|mmu:93734|Mpv17-like protein GO:0031224//intrinsic component of membrane;GO:0042579//microbody;GO:0031224//intrinsic component of membrane;GO:0042579//microbody;GO:0031224//intrinsic component of membrane;GO:0042579//microbody;GO:0031224//intrinsic component of membrane;GO:0042579//microbody;GO:0031224//intrinsic component of membrane;GO:0042579//microbody;GO:0031224//intrinsic component of membrane;GO:0042579//microbody - GO:0010727//negative regulation of hydrogen peroxide metabolic process;GO:0010823//negative regulation of mitochondrion organization;GO:0010727//negative regulation of hydrogen peroxide metabolic process;GO:0010823//negative regulation of mitochondrion organization;GO:0010727//negative regulation of hydrogen peroxide metabolic process;GO:0010823//negative regulation of mitochondrion organization;GO:0010727//negative regulation of hydrogen peroxide metabolic process;GO:0010823//negative regulation of mitochondrion organization;GO:0010727//negative regulation of hydrogen peroxide metabolic process;GO:0010823//negative regulation of mitochondrion organization;GO:0010727//negative regulation of hydrogen peroxide metabolic process;GO:0010823//negative regulation of mitochondrion organization gi|575771864|ref|NP_001276491.1|/2.23531e-50/mpv17-like protein isoform 3 [Mus musculus] 228839 2900 0.843333333 1.16 0.459949921 Up 0.278959344 Tgif2 TGFB-induced factor homeobox 2 K19553|1|5e-132|474|mmu:228839|homeobox protein TGIF2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0007369//gastrulation;GO:0043010//camera-type eye development;GO:0032924//activin receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0030182//neuron differentiation;GO:0007369//gastrulation;GO:0043010//camera-type eye development;GO:0032924//activin receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0030182//neuron differentiation" gi|27734180|ref|NP_775572.1|/4.10057e-131/homeobox protein TGIF2 isoform a [Mus musculus] 171531 4484 0.853333333 1.173333333 0.459431619 Up 0.278959344 Mlph melanophilin K17598|1|2e-09|68.2|dre:553322|synaptotagmin-like protein GO:0005874//microtubule;GO:0032432//actin filament bundle;GO:0048770 GO:0008017//microtubule binding;GO:0043169//cation binding;GO:0017016//Ras GTPase binding;GO:0017022//myosin binding GO:0050931//pigment cell differentiation;GO:0051875//pigment granule localization;GO:0006886//intracellular protein transport gi|87080831|ref|NP_443748.2|/0/melanophilin [Mus musculus] 74195 2891 14.39333333 15.77333333 0.13208683 Up 0.278949942 Elp3 elongator acetyltransferase complex subunit 3 K07739|1|0.0|1062|mmu:74195|elongator complex protein 3 [EC:2.3.1.48] - - - - 77034 2731 21.30333333 23.21666667 0.124081665 Up 0.278818308 2510039O18Rik RIKEN cDNA 2510039O18 gene "K06236|1|8e-07|58.9|clv:102092022|collagen, type I, alpha;K19721|2|2e-06|57.8|myb:102239818|collagen, type V/XI/XXIV/XXVII, alpha;K11345|3|3e-06|57.0|ggo:101138421|inhibitor of growth protein 5" GO:0031224//intrinsic component of membrane - - gi|225543561|ref|NP_084117.2|/0/uncharacterized protein KIAA2013 precursor [Mus musculus] 68841 876 21.59 23.5 0.122297513 Up 0.278818308 Lppos "LIM domain containing preferred translocation partner in lipoma, opposite strand" - - - - - 228852 6371.63 5.37 4.723333333 -0.185116736 Down 0.278780699 Ppp1r16b "protein phosphatase 1, regulatory (inhibitor) subunit 16B" K17459|1|0.0|981|mmu:228852|protein phosphatase 1 regulatory inhibitor subunit 16B GO:0016020//membrane;GO:0016020//membrane - - gi|23346511|ref|NP_694729.1|/0/protein phosphatase 1 regulatory inhibitor subunit 16B [Mus musculus] 14963 1164 0.973333333 0.676666667 -0.524488642 Down 0.278743089 H2-Bl "histocompatibility 2, blastocyst" "K06751|1|0.0|690|mmu:14963|major histocompatibility complex, class I" GO:0031224//intrinsic component of membrane;GO:0044464 - GO:0045953//negative regulation of natural killer cell mediated cytotoxicity "gi|294997253|ref|NP_032225.2|/0/histocompatibility 2, blastocyst precursor [Mus musculus]" 24010 1996 44.72333333 48.12 0.105608923 Up 0.278743089 Ik IK cytokine K13109|1|0.0|840|mmu:24010|IK cytokine GO:0044421;GO:0005634//nucleus GO:0005488//binding GO:0002376//immune system process;GO:0007154//cell communication gi|4090247|emb|CAA06880.1|/0/rer [Mus musculus] 11364 2062 527.5133333 492.39 -0.099406097 Down 0.278677273 Acadm "acyl-Coenzyme A dehydrogenase, medium chain" K00249|1|0.0|847|mmu:11364|acyl-CoA dehydrogenase [EC:1.3.8.7] GO:0043005//neuron projection;GO:0005740//mitochondrial envelope GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0003995//acyl-CoA dehydrogenase activity GO:0006094//gluconeogenesis;GO:0006635//fatty acid beta-oxidation;GO:0009437//carnitine metabolic process;GO:0005977//glycogen metabolic process;GO:0010038//response to metal ion;GO:0006578//amino-acid betaine biosynthetic process;GO:0035051//cardiocyte differentiation;GO:0031960//response to corticosteroid;GO:0006950//response to stress;GO:0051260//protein homooligomerization;GO:0031667//response to nutrient levels "gi|6680618|ref|NP_031408.1|/0/medium-chain specific acyl-CoA dehydrogenase, mitochondrial precursor [Mus musculus]" 56338 2799.71 463.5133333 498.2233333 0.104181749 Up 0.278658468 Txnip thioredoxin interacting protein - GO:0005740//mitochondrial envelope;GO:0005740//mitochondrial envelope GO:0044389//ubiquitin-like protein ligase binding;GO:0030234//enzyme regulator activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0030234//enzyme regulator activity GO:0009605//response to external stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0043627//response to estrogen;GO:0009913//epidermal cell differentiation;GO:0006915//apoptotic process;GO:0000302//response to reactive oxygen species;GO:0006886//intracellular protein transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044092//negative regulation of molecular function;GO:0002347//response to tumor cell;GO:0010038//response to metal ion;GO:0009746;GO:0030522//intracellular receptor signaling pathway;GO:0048523//negative regulation of cellular process;GO:0006952//defense response;GO:0009605//response to external stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0043627//response to estrogen;GO:0009913//epidermal cell differentiation;GO:0006915//apoptotic process;GO:0000302//response to reactive oxygen species;GO:0006886//intracellular protein transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044092//negative regulation of molecular function;GO:0002347//response to tumor cell;GO:0010038//response to metal ion;GO:0009746;GO:0030522//intracellular receptor signaling pathway;GO:0048523//negative regulation of cellular process;GO:0006952//defense response "gi|148706945|gb|EDL38892.1|/0/thioredoxin interacting protein, isoform CRA_a, partial [Mus musculus]" 100504710 1395 0.47 0.74 0.654864514 Up 0.278639663 Nat8f6 N-acetyltransferase 8 (GCN5-related) family member 6 K18309|1|5e-17|91.7|dre:564754|aspartate N-acetyltransferase [EC:2.3.1.17] - - - - 232970 2282 0.243333333 0.476666667 0.970046778 Up 0.278573846 Phldb3 "pleckstrin homology like domain, family B, member 3" K09486|1|2e-26|124|asn:102367994|hypoxia up-regulated 1;K09593|3|3e-07|60.1|aqu:105313571|GRB2-associated-binding protein 1;K18061|4|7e-06|55.5|xma:102234377|myotubularin-related protein 5/13 - - - gi|156616318|ref|NP_001096083.1|/0/pleckstrin homology-like domain family B member 3 [Mus musculus] 330503 2955 4.703333333 4.09 -0.201582739 Down 0.278555042 Gm5113 predicted gene 5113 K09228|1|4e-107|232|ngi:103750680|KRAB domain-containing zinc finger protein - - - gi|674088297|ref|XP_008852062.1|/3.46657e-106/PREDICTED: zinc finger protein 565 isoform X1 [Nannospalax galili] 244418 4780 12.06 10.94666667 -0.139738281 Down 0.278555042 D8Ertd82e "DNA segment, Chr 8, ERATO Doi 82, expressed" K17537|1|0.0|2439|mmu:244418|tyrosine-protein kinase SgK223 [EC:2.7.10.2] - - - gi|161333828|ref|NP_766499.2|/0/tyrosine-protein kinase SgK223 [Mus musculus] 16950 4049 4.623333333 4.013333333 -0.204132396 Down 0.278555042 Loxl3 lysyl oxidase-like 3 K00280|1|0.0|1580|mmu:16950|lysyl oxidase-like protein 2/3/4 [EC:1.4.3.-] GO:0043231//intracellular membrane-bounded organelle;GO:0044421 "GO:0046914//transition metal ion binding;GO:0038024//cargo receptor activity;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor" "GO:0044710;GO:0006351//transcription, DNA-templated;GO:0000904//cell morphogenesis involved in differentiation" gi|31543127|ref|NP_038614.2|/0/lysyl oxidase homolog 3 precursor [Mus musculus] 667823 2496 0.546666667 0.826666667 0.596644306 Up 0.278545639 Trim5 tripartite motif-containing 5 K10648|1|0.0|975|mmu:319236|tripartite motif-containing protein 5 [EC:2.3.2.27] GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002831;GO:0051259//protein oligomerization;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0000165//MAPK cascade;GO:0002758//innate immune response-activating signal transduction gi|890799132|ref|NP_001297531.1|/0/tripartite motif-containing 5 [Mus musculus] 14751 2887 412.5833333 442.56 0.101187518 Up 0.278395201 Gpi1 glucose phosphate isomerase 1 K01810|1|0.0|1137|mmu:14751|glucose-6-phosphate isomerase [EC:5.3.1.9] GO:0031981//nuclear lumen;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane;GO:0044421 "GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses;GO:0005102//receptor binding;GO:0030246//carbohydrate binding" GO:0006007//glucose catabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0044708//single-organism behavior;GO:0009438//methylglyoxal metabolic process;GO:0043066//negative regulation of apoptotic process gi|254553458|ref|NP_032181.2|/0/glucose-6-phosphate isomerase [Mus musculus] 71532 2280 3.826666667 3.286666667 -0.21946309 Down 0.278395201 Fam217b "family with sequence similarity 217, member B" - - - - gi|148675342|gb|EDL07289.1|/0/mCG54925 [Mus musculus] 18103 851.97 435.28 465.2133333 0.095948713 Up 0.278395201 Nme2 NME/NM23 nucleoside diphosphate kinase 2 K00940|1|1e-84|315|mmu:18103|nucleoside-diphosphate kinase [EC:2.7.4.6] GO:0031252//cell leading edge;GO:0043234//protein complex;GO:0005740//mitochondrial envelope;GO:0016020//membrane;GO:0031252//cell leading edge;GO:0043234//protein complex;GO:0005740//mitochondrial envelope;GO:0016020//membrane "GO:0004672//protein kinase activity;GO:0008289//lipid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0032403//protein complex binding;GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0003676//nucleic acid binding;GO:0043169//cation binding;GO:0004672//protein kinase activity;GO:0008289//lipid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0032403//protein complex binding;GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0003676//nucleic acid binding;GO:0043169//cation binding" "GO:0006461//protein complex assembly;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0043434//response to peptide hormone;GO:0001678//cellular glucose homeostasis;GO:0006351//transcription, DNA-templated;GO:0009132//nucleoside diphosphate metabolic process;GO:0006979//response to oxidative stress;GO:0010975//regulation of neuron projection development;GO:0022610;GO:0030216//keratinocyte differentiation;GO:0009209;GO:0002573//myeloid leukocyte differentiation;GO:0070542//response to fatty acid;GO:0006171//cAMP biosynthetic process;GO:0006468//protein phosphorylation;GO:0006461//protein complex assembly;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0043434//response to peptide hormone;GO:0001678//cellular glucose homeostasis;GO:0006351//transcription, DNA-templated;GO:0009132//nucleoside diphosphate metabolic process;GO:0006979//response to oxidative stress;GO:0010975//regulation of neuron projection development;GO:0022610;GO:0030216//keratinocyte differentiation;GO:0009209;GO:0002573//myeloid leukocyte differentiation;GO:0070542//response to fatty acid;GO:0006171//cAMP biosynthetic process;GO:0006468//protein phosphorylation" gi|6679078|ref|NP_032731.1|/1.04977e-83/nucleoside diphosphate kinase B [Mus musculus] 28000 6172.17 41.12666667 44.45 0.112109274 Up 0.278338787 Prpf19 pre-mRNA processing factor 19 K10599|1|0.0|979|rno:246216|pre-mRNA-processing factor 19 [EC:2.3.2.27] - - - - 18195 3766 8.013333333 7.166666667 -0.161100236 Down 0.27831058 Nsf N-ethylmaleimide sensitive fusion protein K06027|1|0.0|1375|mmu:18195|vesicle-fusing ATPase [EC:3.6.4.6] GO:0016020//membrane;GO:0044327//dendritic spine head;GO:0044431//Golgi apparatus part GO:0032550;GO:0000149//SNARE binding;GO:0017016//Ras GTPase binding;GO:0019904//protein domain specific binding;GO:0043169//cation binding;GO:0016887//ATPase activity GO:0030001//metal ion transport;GO:0001881//receptor recycling;GO:0006887//exocytosis;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0001505//regulation of neurotransmitter levels "gi|49518|emb|CAA33678.1|/0/N-ethylmaleimide sensitive fusion protein, partial [Cricetulus griseus]" 66998 2065 7.143333333 7.99 0.161598059 Up 0.27831058 Psmd5 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 5" K06692|1|0.0|934|mmu:66998|26S proteasome non-ATPase regulatory subunit 5 GO:0005838//proteasome regulatory particle GO:0005515//protein binding GO:0044267//cellular protein metabolic process gi|134053913|ref|NP_542121.2|/0/26S proteasome non-ATPase regulatory subunit 5 [Mus musculus] 230649 2330 44.98 41.67 -0.110274561 Down 0.278291775 Atpaf1 ATP synthase mitochondrial F1 complex assembly factor 1 K07555|1|2e-177|625|mmu:230649|ATP synthase mitochondrial F1 complex assembly factor 1 GO:0043231//intracellular membrane-bounded organelle - GO:0065003 gi|344925843|ref|NP_851383.2|/1.89712e-176/ATP synthase mitochondrial F1 complex assembly factor 1 [Mus musculus] 18041 2053 43.02 46.32666667 0.106835355 Up 0.278291775 Nfs1 nitrogen fixation gene 1 (S. cerevisiae) K04487|1|0.0|864|mmu:18041|cysteine desulfurase [EC:2.8.1.7] GO:0044429 GO:0016783//sulfurtransferase activity;GO:0043168//anion binding;GO:0042802//identical protein binding GO:0009108//coenzyme biosynthetic process;GO:0016226//iron-sulfur cluster assembly;GO:0000096//sulfur amino acid metabolic process "gi|161016824|ref|NP_035041.2|/0/cysteine desulfurase, mitochondrial [Mus musculus]" 106894 5146.49 6.99 6.23 -0.166060292 Down 0.278216556 Hmgxb3 HMG box domain containing 3 - - - - gi|145279239|ref|NP_598895.2|/0/HMG domain-containing protein 3 isoform 2 [Mus musculus] 207615 4554.95 6.66 5.903333333 -0.173992371 Down 0.278216556 Wdr37 WD repeat domain 37 K19760|1|1e-24|118|cin:100181614|dynein assembly factor with WDR repeat domains 1 - - - gi|37360172|dbj|BAC98064.1|/0/mKIAA0982 protein [Mus musculus] 212670 2247 0.963333333 1.296666667 0.428700662 Up 0.278188349 Catsper2 "cation channel, sperm associated 2" K16890|1|0.0|935|mmu:212670|cation channel sperm-associated protein 2 GO:0005929//cilium;GO:0005891//voltage-gated calcium channel complex GO:0005216//ion channel activity GO:0048870//cell motility;GO:0019953//sexual reproduction;GO:0032501//multicellular organismal process;GO:0044702//single organism reproductive process;GO:0032502//developmental process gi|124001554|ref|NP_694715.2|/0/cation channel sperm-associated protein 2 [Mus musculus] 219135 3845 9.33 8.38 -0.154926837 Down 0.278169544 Mtmr6 myotubularin related protein 6 K18083|1|0.0|1237|mmu:219135|myotubularin-related protein 6/7/8 [EC:3.1.3.64 3.1.3.95] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system GO:0005227//calcium activated cation channel activity;GO:0004721//phosphoprotein phosphatase activity GO:0006470//protein dephosphorylation;GO:0046474//glycerophospholipid biosynthetic process gi|21450239|ref|NP_659092.1|/0/myotubularin-related protein 6 [Mus musculus] 55951 907 378.9533333 405.0866667 0.096210403 Up 0.278160141 Mpc1 mitochondrial pyruvate carrier 1 - GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008028//monocarboxylic acid transmembrane transporter activity GO:0032787//monocarboxylic acid metabolic process;GO:0006839//mitochondrial transport gi|9055178|ref|NP_061289.1|/1.04302e-57/mitochondrial pyruvate carrier 1 [Mus musculus] 70122 5965.56 1.406666667 1.783333333 0.342295893 Up 0.278122532 Mllt3 "myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3" K15187|1|5e-55|219|pale:102881660|YEATS domain-containing protein 1/3 - - GO:0003002//regionalization;GO:0030111//regulation of Wnt signaling pathway "gi|148699036|gb|EDL30983.1|/4.17121e-54/myeloid/lymphoid or mixed lineage-leukemia translocation to 3 homolog (Drosophila), isoform CRA_a, partial [Mus musculus]" 208943 6733 0.7 1 0.514573173 Up 0.278028508 Myo5c myosin VC K10357|1|0.0|3443|mmu:208943|myosin V GO:0015629//actin cytoskeleton GO:0003779//actin binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 - gi|124486759|ref|NP_001074791.1|/0/unconventional myosin-Vc [Mus musculus] 230162 2999.46 1.583333333 1.226666667 -0.368221747 Down 0.278028508 Zfp189 zinc finger protein 189 K09228|1|0.0|1263|mmu:230162|KRAB domain-containing zinc finger protein - - - - 72776 4248 1 0.703333333 -0.507719502 Down 0.278028508 Sass6 SAS-6 centriolar assembly protein K16487|1|0.0|1110|mmu:72776|spindle assembly abnormal protein 6 GO:0005813//centrosome;GO:0005813//centrosome;GO:0005813//centrosome - GO:0007098//centrosome cycle;GO:0007098//centrosome cycle;GO:0007098//centrosome cycle gi|575771867|ref|NP_001276500.1|/0/spindle assembly abnormal protein 6 homolog isoform 2 [Mus musculus] 20021 1580 43.11333333 46.37 0.105057617 Up 0.278028508 Polr2c polymerase (RNA) II (DNA directed) polypeptide C K03011|1|2e-149|531|cge:100765460|DNA-directed RNA polymerase II subunit RPB3 "GO:0005856//cytoskeleton;GO:0016591//DNA-directed RNA polymerase II, holoenzyme" GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006397//mRNA processing;GO:0044764;GO:0006289//nucleotide-excision repair;GO:0000377 gi|29336059|ref|NP_033116.2|/1.33419e-148/DNA-directed RNA polymerase II subunit RPB3 [Mus musculus] 12915 2586 11.23333333 12.33666667 0.135166544 Up 0.278028508 Atf6b activating transcription factor 6 beta K09049|1|0.0|1014|mmu:12915|cyclic AMP-dependent transcription factor ATF-6 beta GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0005924//cell-substrate adherens junction GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0035966//response to topologically incorrect protein" gi|568998835|ref|XP_006523635.1|/0/PREDICTED: cyclic AMP-dependent transcription factor ATF-6 beta isoform X1 [Mus musculus] 70218 3345 0.836666667 0.556666667 -0.587839261 Down 0.277990898 Kif18b kinesin family member 18B K10401|1|5e-135|484|cmk:103189451|kinesin family member 18/19 GO:0015630//microtubule cytoskeleton;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0032550;GO:0003774//motor activity GO:0000087//mitotic M phase;GO:0006928//movement of cell or subcellular component;GO:0050794//regulation of cellular process gi|254939627|ref|NP_932063.2|/0/kinesin-like protein KIF18B [Mus musculus] 105847 2906 21.73666667 23.58333333 0.117636928 Up 0.277906277 Lmf2 lipase maturation factor 2 K00858|1|1e-07|62.0|tgu:100220598|NAD+ kinase [EC:2.7.1.23] GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|30725786|ref|NP_849250.1|/0/lipase maturation factor 2 [Mus musculus] 50778 1343 0.043333333 0.213333333 2.299560282 Up 0.277774644 Rgs1 regulator of G-protein signaling 1 K16449|1|2e-115|418|mmu:50778|regulator of G-protein signaling - - - gi|237681187|ref|NP_056626.2|/1.31883e-114/regulator of G-protein signaling 1 [Mus musculus] 446211 1175 0.21 0.043333333 -2.276840205 Down 0.277774644 AY702102 cDNA sequence AY702102 - - - - - 20480 4492 21.06333333 22.90666667 0.121033771 Up 0.277727632 Clpb ClpB caseinolytic peptidase B K03695|1|0.0|1324|mmu:20480|ATP-dependent Clp protease ATP-binding subunit ClpB GO:0043231//intracellular membrane-bounded organelle GO:0016462//pyrophosphatase activity;GO:0032550 GO:0009408//response to heat gi|6677983|ref|NP_033217.1|/0/caseinolytic peptidase B protein homolog [Mus musculus] 72831 3976.27 15.19333333 13.85 -0.133552448 Down 0.277718229 Dhx30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 K13185|1|0.0|2251|mmu:72831|ATP-dependent RNA helicase DHX30 [EC:3.6.4.13] - "GO:0032550;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0042623//ATPase activity, coupled" - gi|13111310|dbj|BAB32789.1|/0/HELG [Mus musculus musculus] 56752 2834 14.34 15.68 0.128880535 Up 0.277718229 Aldh9a1 "aldehyde dehydrogenase 9, subfamily A1" K00149|1|0.0|1042|mmu:56752|aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0042802//identical protein binding;GO:0000166//nucleotide binding;GO:0004029//aldehyde dehydrogenase (NAD) activity GO:0006578//amino-acid betaine biosynthetic process;GO:0044710;GO:0042133//neurotransmitter metabolic process;GO:0044767//single-organism developmental process gi|115334671|ref|NP_064377.2|/0/4-trimethylaminobutyraldehyde dehydrogenase precursor [Mus musculus] 107338 6422 15.21 13.86666667 -0.133399125 Down 0.277718229 Gbf1 golgi-specific brefeldin A-resistance factor 1 K18443|1|0.0|3487|mmu:107338|golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 GO:0044432;GO:0044431//Golgi apparatus part;GO:0042579//microbody GO:0005488//binding - gi|52138536|ref|NP_849261.2|/0/golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 [Mus musculus] 13113 2955 0.216666667 0.046666667 -2.215012891 Down 0.277690022 Cyp3a13 "cytochrome P450, family 3, subfamily a, polypeptide 13" "K07424|1|0.0|860|mmu:13113|cytochrome P450, family 3, subfamily A [EC:1.14.14.1];K17689|4|0.0|683|tup:102494214|cytochrome P450, family 3, subfamily A, polypeptide 4 [EC:1.14.13.32 1.14.13.67 1.14.13.97 1.14.13.157 1.14.13.-]" GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0007606//sensory perception of chemical stimulus;GO:0055114//oxidation-reduction process;GO:0010467//gene expression;GO:0017144//drug metabolic process;GO:0009820//alkaloid metabolic process gi|6681115|ref|NP_031845.1|/0/cytochrome P450 3A13 [Mus musculus] 13063 3059 303.9466667 325.3966667 0.098381275 Up 0.277671217 Cycs "cytochrome c, somatic" K08738|1|6e-56|222|rno:25309|cytochrome c GO:0005743//mitochondrial inner membrane;GO:0044425 GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0009055//electron carrier activity "GO:0000737//DNA catabolic process, endonucleolytic;GO:0072593//reactive oxygen species metabolic process;GO:0022904//respiratory electron transport chain;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006950//response to stress" "gi|6681095|ref|NP_031834.1|/5.08261e-55/cytochrome c, somatic [Mus musculus]" 21766 1454 41.79666667 44.98333333 0.106002681 Up 0.277586596 Tex261 testis expressed gene 261 - GO:0031224//intrinsic component of membrane - GO:0006915//apoptotic process gi|6678297|ref|NP_033383.1|/2.27632e-107/protein TEX261 [Mus musculus] 15958 3949 3.72 4.293333333 0.206795566 Up 0.277539584 Ifit2 interferon-induced protein with tetratricopeptide repeats 2 K14217|1|4e-92|342|ecb:100058990|interferon-induced protein with tetratricopeptide repeats 1 GO:0043231//intracellular membrane-bounded organelle - GO:0043393//regulation of protein binding;GO:0006952//defense response;GO:0002252;GO:0035455//response to interferon-alpha;GO:0051707//response to other organism;GO:0006915//apoptotic process gi|6680363|ref|NP_032358.1|/0/interferon-induced protein with tetratricopeptide repeats 2 [Mus musculus] 71521 4146 4.196666667 3.63 -0.209274329 Down 0.277539584 Pds5a PDS5 cohesin associated factor A K11267|1|0.0|2519|mmu:71521|sister chromatid cohesion protein PDS5 GO:0044427;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0005488//binding GO:0006260//DNA replication;GO:0000087//mitotic M phase gi|124486765|ref|NP_001074790.1|/0/sister chromatid cohesion protein PDS5 homolog A [Mus musculus] 209760 4493 2.173333333 1.763333333 -0.301604242 Down 0.277511377 Tmc7 transmembrane channel-like gene family 7 K10877|1|2e-14|85.1|tsp:Tsp_10860|DNA repair and recombination protein RAD54B [EC:3.6.4.-] GO:0031224//intrinsic component of membrane - GO:0044765//single-organism transport gi|31542282|ref|NP_766064.2|/0/transmembrane channel-like protein 7 [Mus musculus] 228410 2643.17 2.736666667 3.223333333 0.236133668 Up 0.277501975 Cstf3 "cleavage stimulation factor, 3' pre-RNA, subunit 3" K14408|1|2e-23|113|myd:102755295|cleavage stimulation factor subunit 3 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0000377;GO:0031124//mRNA 3'-end processing;GO:0006366//transcription from RNA polymerase II promoter;GO:0000377;GO:0031124//mRNA 3'-end processing;GO:0006366//transcription from RNA polymerase II promoter;GO:0000377;GO:0031124//mRNA 3'-end processing;GO:0006366//transcription from RNA polymerase II promoter gi|640779225|ref|XP_008065377.1|/5.70124e-36/PREDICTED: uncharacterized protein LOC103269619 [Tarsius syrichta] 13046 4972.14 22.15 20.32333333 -0.124169654 Down 0.277492572 Celf1 "CUGBP, Elav-like family member 1" K13207|1|0.0|718|cfr:102507368|CUG-BP- and ETR3-like factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0005515//protein binding GO:0000245//spliceosomal complex assembly;GO:0035264//multicellular organism growth;GO:0007281//germ cell development;GO:0000245//spliceosomal complex assembly;GO:0035264//multicellular organism growth;GO:0007281//germ cell development;GO:0000245//spliceosomal complex assembly;GO:0035264//multicellular organism growth;GO:0007281//germ cell development gi|589943475|ref|XP_006984439.1|/0/PREDICTED: CUGBP Elav-like family member 1 isoform X2 [Peromyscus maniculatus bairdii] 238875 2055 0.033333333 0.196666667 2.560714954 Up 0.277473767 Gapt "Grb2-binding adaptor, transmembrane" - GO:0031224//intrinsic component of membrane - GO:0046649//lymphocyte activation gi|29244178|ref|NP_808381.1|/1.05193e-66/protein GAPT [Mus musculus] 54624 1953 41.41333333 44.58333333 0.106409157 Up 0.277417353 Paf1 "Paf1, RNA polymerase II complex component" K15174|1|0.0|754|pale:102895049|RNA polymerase II-associated factor 1 GO:0008023//transcription elongation factor complex GO:0001099//basal RNA polymerase II transcription machinery binding GO:0032496//response to lipopolysaccharide;GO:0007166//cell surface receptor signaling pathway;GO:0006513//protein monoubiquitination;GO:0031124//mRNA 3'-end processing;GO:0035987//endodermal cell differentiation;GO:0016574//histone ubiquitination;GO:0000084//mitotic S phase;GO:0030099//myeloid cell differentiation;GO:0006368//transcription elongation from RNA polymerase II promoter gi|149722114|ref|XP_001498010.1|/0/PREDICTED: RNA polymerase II-associated factor 1 homolog [Equus caballus] 56417 5889.66 6.213333333 6.966666667 0.165101082 Up 0.277398548 Adar "adenosine deaminase, RNA-specific" K12968|1|0.0|2165|mmu:56417|double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37] GO:0031981//nuclear lumen;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0005681//spliceosomal complex GO:0004000//adenosine deaminase activity;GO:0043169//cation binding;GO:0003723//RNA binding;GO:0043566//structure-specific DNA binding;GO:0004000//adenosine deaminase activity;GO:0043169//cation binding;GO:0003723//RNA binding;GO:0043566//structure-specific DNA binding;GO:0004000//adenosine deaminase activity;GO:0043169//cation binding;GO:0003723//RNA binding;GO:0043566//structure-specific DNA binding "GO:0006351//transcription, DNA-templated;GO:0016458//gene silencing;GO:0016553//base conversion or substitution editing;GO:0051707//response to other organism;GO:0006469//negative regulation of protein kinase activity;GO:0019079//viral genome replication;GO:0006915//apoptotic process;GO:0006886//intracellular protein transport;GO:0034097//response to cytokine;GO:0006396//RNA processing;GO:0002252;GO:0006952//defense response;GO:0006351//transcription, DNA-templated;GO:0016458//gene silencing;GO:0016553//base conversion or substitution editing;GO:0051707//response to other organism;GO:0006469//negative regulation of protein kinase activity;GO:0019079//viral genome replication;GO:0006915//apoptotic process;GO:0006886//intracellular protein transport;GO:0034097//response to cytokine;GO:0006396//RNA processing;GO:0002252;GO:0006952//defense response;GO:0006351//transcription, DNA-templated;GO:0016458//gene silencing;GO:0016553//base conversion or substitution editing;GO:0051707//response to other organism;GO:0006469//negative regulation of protein kinase activity;GO:0019079//viral genome replication;GO:0006915//apoptotic process;GO:0006886//intracellular protein transport;GO:0034097//response to cytokine;GO:0006396//RNA processing;GO:0002252;GO:0006952//defense response" gi|226371679|ref|NP_062629.3|/0/double-stranded RNA-specific adenosine deaminase isoform 1 [Mus musculus] 19766 4512 2.13 2.566666667 0.269042515 Up 0.277398548 Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 K02861|1|0.0|1343|mmu:19766|receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044425 GO:0004672//protein kinase activity;GO:0032550;GO:0019904//protein domain specific binding;GO:0032813//tumor necrosis factor receptor superfamily binding GO:0001932//regulation of protein phosphorylation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0097193//intrinsic apoptotic signaling pathway;GO:0012502//induction of programmed cell death;GO:0007254//JNK cascade;GO:0001819//positive regulation of cytokine production;GO:0097191//extrinsic apoptotic signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0022898//regulation of transmembrane transporter activity;GO:0051259//protein oligomerization;GO:0030163//protein catabolic process;GO:0034612//response to tumor necrosis factor gi|34328467|ref|NP_033094.3|/0/receptor-interacting serine/threonine-protein kinase 1 [Mus musculus] 26563 5803 1.1 0.79 -0.477578965 Down 0.277351536 Ror1 receptor tyrosine kinase-like orphan receptor 1 K05122|1|0.0|1774|mmu:26563|receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1] - - - - 18946 1619 0.036666667 0.2 2.447458977 Up 0.277351536 Pnliprp1 pancreatic lipase related protein 1 K14074|1|0.0|986|mmu:18946|pancreatic lipase-related protein 1 [EC:3.1.1.3] GO:0044421 GO:0046872//metal ion binding;GO:0016298//lipase activity GO:0031960//response to corticosteroid;GO:0044767//single-organism developmental process;GO:0044238//primary metabolic process gi|9256628|ref|NP_061362.1|/0/inactive pancreatic lipase-related protein 1 precursor [Mus musculus] 75909 2773 21.47333333 23.29333333 0.117370948 Up 0.277313927 Vmp1 vacuole membrane protein 1 - GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005774//vacuolar membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0007275//multicellular organism development;GO:0007155//cell adhesion;GO:0022607//cellular component assembly;GO:0006914//autophagy gi|568976211|ref|XP_006534465.1|/0/PREDICTED: vacuole membrane protein 1 isoform X2 [Mus musculus] 77490 972.35 1.353333333 1.726666667 0.351472371 Up 0.277304524 E130218I03Rik RIKEN cDNA E130218I03 gene K14821|1|1e-15|53.9|cfr:102507280|bud site selection protein 20 - - - - 70317 2023 5.066666667 4.43 -0.193730219 Down 0.277295122 Arl16 ADP-ribosylation factor-like 16 K07942|1|1e-14|84.3|loa:LOAG_03618|ADP-ribosylation factor-like protein 1 - GO:0032550 - gi|91199554|ref|NP_932112.2|/2.88222e-93/ADP-ribosylation factor-like protein 16 [Mus musculus] 72886 1324 5.16 4.52 -0.191048293 Down 0.277295122 Ccdc94 coiled-coil domain containing 94 K13115|1|1e-16|90.5|cmk:103187566|coiled-coil domain-containing protein 130 - - - gi|21312171|ref|NP_082657.1|/6.83822e-124/coiled-coil domain-containing protein 94 [Mus musculus] 114874 5099 2.283333333 2.733333333 0.259519922 Up 0.277257513 Ddhd1 DDHD domain containing 1 K13619|1|0.0|1389|rno:305816|phospholipase DDHD1 [EC:3.1.1.-] - - - gi|111955212|ref|NP_001036184.1|/0/phospholipase DDHD1 isoform 3 [Mus musculus] 627800 1604 0.036666667 0.193333333 2.398549376 Up 0.27724811 Gm20757 "predicted gene, 20757" - - - - - 17219 3045.88 3.47 2.96 -0.229338487 Down 0.277238708 Mcm6 minichromosome maintenance complex component 6 K02542|1|0.0|1551|mmu:17219|DNA replication licensing factor MCM6 [EC:3.6.4.12] GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0003678//DNA helicase activity;GO:0032550;GO:0005515//protein binding;GO:0043566//structure-specific DNA binding;GO:0003678//DNA helicase activity;GO:0032550;GO:0005515//protein binding;GO:0043566//structure-specific DNA binding GO:0044772//mitotic cell cycle phase transition;GO:0006261//DNA-dependent DNA replication;GO:0051320;GO:0044763;GO:0006261//DNA-dependent DNA replication gi|922960012|ref|NP_001300624.1|/0/DNA replication licensing factor MCM6 isoform 2 [Mus musculus] 321008 3366 2.883333333 3.39 0.233547641 Up 0.277238708 6330408A02Rik RIKEN cDNA 6330408A02 gene - - - - gi|50053999|ref|NP_796286.2|/0/uncharacterized protein C19orf68 homolog [Mus musculus] 210992 1605 3.453333333 2.946666667 -0.228905728 Down 0.277238708 Lpcat1 lysophosphatidylcholine acyltransferase 1 K13510|1|0.0|995|mmu:210992|lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0016413//O-acetyltransferase activity GO:0006644//phospholipid metabolic process;GO:0043010//camera-type eye development;GO:0048875//chemical homeostasis within a tissue;GO:0009896;GO:0033239 gi|148747363|ref|NP_663351.3|/0/lysophosphatidylcholine acyltransferase 1 [Mus musculus] 100041085 1782 3.44 2.93 -0.2315079 Down 0.277238708 Mfsd4b3 major facilitator superfamily domain containing 4B3 "K08175|1|0.0|696|cge:100771784|MFS transporter, FHS family, Na+ dependent glucose transporter 1" GO:0005886//plasma membrane;GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0044763;GO:0008645//hexose transport;GO:0030001//metal ion transport gi|625273060|ref|XP_007628110.1|/0/PREDICTED: LOW QUALITY PROTEIN: sodium-dependent glucose transporter 1C [Cricetulus griseus] 70564 1616.38 14.85666667 13.53666667 -0.134237934 Down 0.277182293 Fam213a "family with sequence similarity 213, member A" K15717|1|8e-14|81.3|oas:101120767|prostamide/prostaglandin F2alpha synthase [EC:1.11.1.20] - - - - 229504 2893 5.266666667 5.953333333 0.176807522 Up 0.277172891 Isg20l2 interferon stimulated exonuclease gene 20-like 2 K18329|1|0.0|643|mmu:229504|interferon-stimulated 20 kDa exonuclease-like 2 [EC:3.1.-.-] GO:0031981//nuclear lumen GO:0004518//nuclease activity GO:0022613//ribonucleoprotein complex biogenesis gi|29244084|ref|NP_808331.1|/0/interferon-stimulated 20 kDa exonuclease-like 2 [Mus musculus] 13871 3547 5.05 5.736666667 0.183929304 Up 0.277172891 Ercc2 "excision repair cross-complementing rodent repair deficiency, complementation group 2" K10844|1|0.0|1469|mmu:13871|DNA excision repair protein ERCC-2 [EC:3.6.4.12] GO:0005667//transcription factor complex;GO:0005819//spindle "GO:0004674//protein serine/threonine kinase activity;GO:0003678//DNA helicase activity;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding" GO:0030097//hemopoiesis;GO:0006915//apoptotic process;GO:0022010//central nervous system myelination;GO:0043009//chordate embryonic development;GO:0043062//extracellular structure organization;GO:0022402//cell cycle process;GO:0001942//hair follicle development;GO:0001503//ossification;GO:0009411//response to UV;GO:0012502//induction of programmed cell death;GO:0040007//growth;GO:0006366//transcription from RNA polymerase II promoter;GO:0006464//cellular protein modification process;GO:0051099//positive regulation of binding;GO:0009913//epidermal cell differentiation;GO:0048469//cell maturation;GO:0006289//nucleotide-excision repair gi|31542614|ref|NP_031975.2|/0/TFIIH basal transcription factor complex helicase XPD subunit [Mus musculus] 74775 2167 5.89 5.196666667 -0.180681112 Down 0.277172891 Lmbr1l limb region 1 like K00858|1|7e-13|78.6|smm:Smp_126160|NAD+ kinase [EC:2.7.1.23] GO:0031224//intrinsic component of membrane - GO:0016192//vesicle-mediated transport "gi|148672207|gb|EDL04154.1|/0/limb region 1 like, isoform CRA_a [Mus musculus]" 319801 3653 21.74 23.55 0.115375119 Up 0.277125879 Tigar Trp53 induced glycolysis repulatory phosphatase "K14634|1|3e-151|539|mmu:319801|fructose-2,6-bisphosphatase [EC:3.1.3.46]" - - - - 100502959 627 0.253333333 0.483333333 0.931981577 Up 0.277097672 AV051173 expressed sequence AV051173 - - - - - 17984 1652 4.676666667 4.08 -0.196911451 Down 0.277069465 Ndn necdin K19482|1|1e-159|565|mmu:17984|necdin - - - - 97159 1109 10.48 11.56 0.141502681 Up 0.277069465 A430005L14Rik RIKEN cDNA A430005L14 gene - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|247300747|ref|NP_780496.2|/1.75153e-111/UPF0688 protein C1orf174 homolog isoform 1 [Mus musculus] 56715 2705.43 11.82333333 10.74 -0.138642836 Down 0.277069465 Rabgef1 RAB guanine nucleotide exchange factor (GEF) 1 K20131|1|0.0|892|rno:360797|Rab5 GDP/GTP exchange factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0003676//nucleic acid binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0003676//nucleic acid binding;GO:0019787//ubiquitin-like protein transferase activity GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0007265//Ras protein signal transduction;GO:0032675//regulation of interleukin-6 production;GO:0006898//receptor-mediated endocytosis;GO:0033007//negative regulation of mast cell activation involved in immune response;GO:0002431//Fc receptor mediated stimulatory signaling pathway;GO:0045184//establishment of protein localization;GO:0006954//inflammatory response;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0007265//Ras protein signal transduction;GO:0032675//regulation of interleukin-6 production;GO:0006898//receptor-mediated endocytosis;GO:0033007//negative regulation of mast cell activation involved in immune response;GO:0002431//Fc receptor mediated stimulatory signaling pathway;GO:0045184//establishment of protein localization;GO:0006954//inflammatory response gi|568938152|ref|XP_006504510.1|/0/PREDICTED: rab5 GDP/GTP exchange factor isoform X2 [Mus musculus] 432572 6665.75 0.686666667 0.426666667 -0.686500527 Down 0.27705066 Specc1 sperm antigen with calponin homology and coiled-coil domains 1 K10352|1|2e-22|112|amj:102574445|myosin heavy chain;K16808|5|5e-21|107|lcm:102358517|nuclear mitotic apparatus protein 1 - - - gi|529250185|ref|NP_001268747.1|/0/cytospin-B isoform 1 [Mus musculus] 235043 873.38 38.25333333 41.35333333 0.112418157 Up 0.277022453 Tmem205 transmembrane protein 205 K07884|1|6e-37|157|phd:102336230|Ras-related protein Rab-3D GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|359718989|ref|NP_001240796.1|/1.28137e-102/transmembrane protein 205 isoform 1 [Mus musculus] 100042784 1870 0.923333333 0.636666667 -0.536313338 Down 0.276900222 Prdm11 PR domain containing 11 K17541|1|6e-31|138|bfo:BRAFLDRAFT_101363|SCY1-like protein 2;K09228|2|5e-21|105|cmk:103175007|KRAB domain-containing zinc finger protein;K12463|3|3e-19|99.4|gja:107124194|PR domain zinc finger protein 4 - - - - 235312 1378.84 3.7 3.173333333 -0.221526198 Down 0.276881417 C1qtnf5 C1q and tumor necrosis factor related protein 5 K05502|1|1e-37|161|xma:102230322|bone morphogenetic protein 1 [EC:3.4.24.19] "GO:0043296//apical junction complex;GO:0044459;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005578//proteinaceous extracellular matrix;GO:0043296//apical junction complex;GO:0044459;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005578//proteinaceous extracellular matrix;GO:0043296//apical junction complex;GO:0044459;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005578//proteinaceous extracellular matrix" GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0043010//camera-type eye development;GO:0001754//eye photoreceptor cell differentiation;GO:0043010//camera-type eye development;GO:0051259//protein oligomerization;GO:0043583//ear development;GO:0001754//eye photoreceptor cell differentiation;GO:0015031//protein transport;GO:0043010//camera-type eye development;GO:0051259//protein oligomerization;GO:0043583//ear development;GO:0001754//eye photoreceptor cell differentiation;GO:0015031//protein transport;GO:0043010//camera-type eye development;GO:0001754//eye photoreceptor cell differentiation;GO:0043010//camera-type eye development;GO:0051259//protein oligomerization;GO:0043583//ear development;GO:0001754//eye photoreceptor cell differentiation;GO:0015031//protein transport gi|625226709|ref|XP_007652720.1|/1.32277e-106/PREDICTED: complement C1q tumor necrosis factor-related protein 5 isoform X1 [Cricetulus griseus] 21916 2887 216.4533333 232.75 0.10472515 Up 0.276768589 Tmod1 tropomodulin 1 K10370|1|0.0|639|mmu:21916|tropomodulin GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0005856//cytoskeleton;GO:0043292//contractile fiber GO:0008092//cytoskeletal protein binding GO:0003012//muscle system process;GO:0007626//locomotory behavior;GO:0014866//skeletal myofibril assembly gi|537231422|gb|ERE84151.1|/0/tropomodulin-1 [Cricetulus griseus] 319467 2507 0.98 1.306666667 0.415037499 Up 0.276721577 A930002C04Rik RIKEN cDNA A930002C04 gene - - - - - 381287 1760 0.983333333 1.313333333 0.417480675 Up 0.276721577 A530032D15Rik RIKEN cDNA A530032D15Rik gene K15413|1|1e-27|127|cfa:477402|nuclear autoantigen Sp-100 - GO:0043169//cation binding - gi|126215538|ref|NP_998780.2|/9.39405e-122/SP140 nuclear body protein family member [Mus musculus] 74137 3108 1.67 2.066666667 0.307457612 Up 0.276683967 Nuak2 "NUAK family, SNF1-like kinase, 2" "K08800|1|0.0|1134|mmu:74137|NUAK family, SNF1-like kinase [EC:2.7.11.1]" - GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding GO:0009267//cellular response to starvation;GO:0006915//apoptotic process;GO:0007010//cytoskeleton organization;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0009267//cellular response to starvation;GO:0006915//apoptotic process;GO:0007010//cytoskeleton organization;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process gi|303324594|ref|NP_001181954.1|/0/NUAK family SNF1-like kinase 2 isoform A [Mus musculus] 72895 6470 8.16 7.326666667 -0.155412172 Down 0.276674565 Setd5 SET domain containing 5 K18086|1|8e-135|485|ola:101159908|myotubularin-related protein 14 [EC:3.1.3.64 3.1.3.95];K09189|3|8e-133|478|cge:100756731|histone-lysine N-methyltransferase MLL5 [EC:2.1.1.43] - - - gi|28972834|dbj|BAC65833.1|/0/mKIAA1757 protein [Mus musculus] 80517 2744 20.82666667 22.61 0.118529039 Up 0.276524127 Herpud2 HERPUD family member 2 K14027|1|3e-56|223|shr:100917121|homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein GO:0016020//membrane - - gi|10181160|ref|NP_065611.1|/1.81973e-173/homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein [Mus musculus] 668917 1079 0.426666667 0.683333333 0.6794801 Up 0.276505322 Zfp133-ps "zinc finger protein 133, pseudogene" K09228|1|7e-06|53.9|cge:100767427|KRAB domain-containing zinc finger protein - - - gi|74205991|dbj|BAE23257.1|/7.19825e-30/unnamed protein product [Mus musculus] 791359 540 0.286666667 0.1 -1.519374159 Down 0.276495919 Gm9961 predicted gene 9961 - - - - "gi|148664939|gb|EDK97355.1|/3.11089e-66/mCG144816, partial [Mus musculus]" 69750 762 0.4 0.19 -1.074000581 Down 0.276486517 2410021H03Rik RIKEN cDNA 2410021H03 gene - - - - - 68477 6165 10.8 11.87333333 0.136693703 Up 0.276467712 Rmnd5a required for meiotic nuclear division 5 homolog A K18624|1|1e-15|89.4|nve:NEMVE_v1g194411|macrophage erythroblast attacher - - - gi|958737460|ref|XP_014708275.1|/0/PREDICTED: protein RMD5 homolog A [Equus asinus] 85031 1994 12.00333333 10.93 -0.135141698 Down 0.276467712 Pla1a phospholipase A1 member A K13618|1|0.0|936|mmu:85031|phospholipase A1 member A [EC:3.1.1.-] - GO:0003824//catalytic activity GO:0006629//lipid metabolic process gi|164519080|ref|NP_598863.3|/0/phospholipase A1 member A precursor [Mus musculus] 140859 2832 1.02 0.723333333 -0.49583661 Down 0.276411298 Nek8 NIMA (never in mitosis gene a)-related expressed kinase 8 K08857|1|0.0|1241|mmu:140859|NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] GO:0005929//cilium;GO:0043232 GO:0043169//cation binding;GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|19263332|ref|NP_543125.1|/0/serine/threonine-protein kinase Nek8 [Mus musculus] 75051 1731 0.15 0.35 1.222392421 Up 0.276354884 Ccdc173 coiled-coil domain containing 173 K12484|1|5e-11|72.0|ola:101164078|Rab11 family-interacting protein 1/2/5;K20478|4|3e-07|59.3|dre:557772|golgin subfamily B member 1 - - - gi|118150478|ref|NP_001071152.1|/0/coiled-coil domain-containing protein 173 [Mus musculus] 230721 2896.32 199.0233333 213.58 0.101838976 Up 0.276307872 Pabpc4 "poly(A) binding protein, cytoplasmic 4" K13126|1|0.0|1184|mmu:230721|polyadenylate-binding protein GO:0035770//ribonucleoprotein granule;GO:0035770//ribonucleoprotein granule GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding;GO:0008187//poly-pyrimidine tract binding;GO:0003729//mRNA binding - gi|34419622|ref|NP_570951.2|/0/polyadenylate-binding protein 4 isoform 1 [Mus musculus] 22192 1185.55 216.78 202.3 -0.099735341 Down 0.276307872 Ube2m ubiquitin-conjugating enzyme E2M K10579|1|2e-103|378|lve:103087191|ubiquitin-conjugating enzyme E2 M - GO:0032550;GO:0070739//protein-glutamic acid ligase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0032550;GO:0070739//protein-glutamic acid ligase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0032550;GO:0070739//protein-glutamic acid ligase activity;GO:0019787//ubiquitin-like protein transferase activity GO:0032446//protein modification by small protein conjugation;GO:0043065//positive regulation of apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0043065//positive regulation of apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0043065//positive regulation of apoptotic process gi|4507791|ref|NP_003960.1|/1.87065e-102/NEDD8-conjugating enzyme Ubc12 [Homo sapiens] 21672 1470.32 211.2833333 225.8033333 0.095887816 Up 0.276307872 Prdx2 peroxiredoxin 2 K03386|1|2e-111|405|mmu:21672|peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15] - - - - 224938 4629.19 22.84666667 21.07666667 -0.116336972 Down 0.276298469 Pja2 "praja 2, RING-H2 motif containing" K10634|1|0.0|1139|mmu:224938|E3 ubiquitin-protein ligase Praja2 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane GO:0051018//protein kinase A binding;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0051018//protein kinase A binding;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0007613//memory;GO:0032446//protein modification by small protein conjugation;GO:0007613//memory;GO:0032446//protein modification by small protein conjugation gi|28972221|dbj|BAC65564.1|/0/mKIAA0438 protein [Mus musculus] 66384 889 21.16 22.93 0.115896727 Up 0.276298469 Srp19 signal recognition particle 19 K03105|1|1e-71|272|mmu:66384|signal recognition particle subunit SRP19 - - - gi|160333840|ref|NP_079803.2|/7.86846e-71/signal recognition particle 19 kDa protein [Mus musculus] 64540 1360.25 20.08333333 21.85666667 0.122074654 Up 0.276298469 Tspan4 tetraspanin 4 K17294|1|3e-129|464|mmu:64540|tetraspanin-4 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148686163|gb|EDL18110.1|/1.61642e-132/tetraspanin 4, isoform CRA_c [Mus musculus]" 338346 2297 0.253333333 0.076666667 -1.724365557 Down 0.276242055 Gpr21 G protein-coupled receptor 21 K04318|1|0.0|647|mmu:338346|G protein-coupled receptor 21 GO:0016021//integral component of membrane GO:0004888//transmembrane signaling receptor activity GO:0008286//insulin receptor signaling pathway;GO:0035264//multicellular organism growth;GO:0033500//carbohydrate homeostasis gi|28893547|ref|NP_796357.1|/0/probable G-protein coupled receptor 21 [Mus musculus] 16157 1761 36.92 39.90333333 0.112106714 Up 0.276213848 Il11ra1 "interleukin 11 receptor, alpha chain 1" K05056|1|0.0|797|mmu:16157|interleukin 11 receptor alpha GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004896//cytokine receptor activity;GO:0046983//protein dimerization activity;GO:0019838//growth factor binding;GO:0004896//cytokine receptor activity;GO:0046983//protein dimerization activity;GO:0019838//growth factor binding;GO:0004896//cytokine receptor activity;GO:0046983//protein dimerization activity;GO:0019838//growth factor binding GO:0001893//maternal placenta development;GO:0019221//cytokine-mediated signaling pathway;GO:0008283//cell proliferation;GO:0001893//maternal placenta development;GO:0019221//cytokine-mediated signaling pathway;GO:0008283//cell proliferation;GO:0001893//maternal placenta development;GO:0019221//cytokine-mediated signaling pathway;GO:0008283//cell proliferation gi|7110651|ref|NP_034679.1|/0/interleukin-11 receptor subunit alpha-1 precursor [Mus musculus] 72723 3728 0.89 1.21 0.443129806 Up 0.276185641 Zfp74 zinc finger protein 74 K09228|1|0.0|1409|mmu:72723|KRAB domain-containing zinc finger protein GO:0044464 GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|161353500|ref|NP_848471.2|/0/zinc finger protein 569 [Mus musculus] 218734 2420.46 5.036666667 5.716666667 0.182704916 Up 0.276072812 3830406C13Rik RIKEN cDNA 3830406C13 gene - - - - gi|568985378|ref|XP_006518056.1|/2.25901e-64/PREDICTED: uncharacterized protein C3orf14 homolog isoform X3 [Mus musculus] 66106 1103.71 202.0333333 188.43 -0.100564667 Down 0.276072812 Smpx "small muscle protein, X-linked" - GO:0005924//cell-substrate adherens junction;GO:0043231//intracellular membrane-bounded organelle;GO:0031672//A band;GO:0005924//cell-substrate adherens junction;GO:0043231//intracellular membrane-bounded organelle;GO:0031672//A band;GO:0005924//cell-substrate adherens junction;GO:0043231//intracellular membrane-bounded organelle;GO:0031672//A band - GO:0006936//muscle contraction;GO:0006936//muscle contraction;GO:0006936//muscle contraction gi|357588496|ref|NP_001239520.1|/1.3356e-36/small muscular protein [Mus musculus] 71778 3422 5.706666667 5.026666667 -0.183046273 Down 0.276072812 Klhl5 kelch-like 5 K10442|1|0.0|1430|nle:100606607|kelch-like protein 1/4/5 GO:0043232 GO:0008092//cytoskeletal protein binding - gi|817319353|ref|XP_012330374.1|/0/PREDICTED: kelch-like protein 5 isoform X1 [Aotus nancymaae] 70333 2248 13.25333333 14.53666667 0.133341234 Up 0.275969386 Cd3eap "CD3E antigen, epsilon polypeptide associated protein" - GO:0044452//nucleolar part - "GO:0006351//transcription, DNA-templated" "gi|148691191|gb|EDL23138.1|/0/CD3E antigen, epsilon polypeptide associated protein, partial [Mus musculus]" 23922 1103 20.65 22.40333333 0.117571621 Up 0.275969386 Jtb jumping translocation breakpoint K06109|1|5e-18|94.4|clv:102095222|Ras-related protein Rab-13;K11110|2|2e-07|58.9|ptg:102964904|telomeric repeat-binding factor 1 GO:0005815//microtubule organizing center;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0019900//kinase binding GO:0000910//cytokinesis;GO:0006915//apoptotic process;GO:0000087//mitotic M phase;GO:0001934//positive regulation of protein phosphorylation;GO:0008283//cell proliferation gi|74226894|dbj|BAE27091.1|/1.18078e-59/unnamed protein product [Mus musculus] 20401 2515 3.54 4.096666667 0.21070115 Up 0.275959983 Sh3bp1 SH3-domain binding protein 1 K19269|1|2e-176|621|pbi:103065057|phosphoglycolate phosphatase [EC:3.1.3.18 3.1.3.48];K18470|2|3e-24|116|cqu:CpipJ_CPIJ002097|Rho GTPase-activating protein 1;K08878|5|2e-22|110|nve:NEMVE_v1g239294|breakpoint cluster region protein [EC:2.7.11.1] - - - - 223664 2277 3.52 4.08 0.212993723 Up 0.275959983 Lrrc14 leucine rich repeat containing 14 - - - - gi|564360651|ref|XP_006241922.1|/0/PREDICTED: leucine-rich repeat-containing protein 14 isoform X2 [Rattus norvegicus] 192166 4573 1.88 1.496666667 -0.328979718 Down 0.275912972 Sardh sarcosine dehydrogenase K00314|1|0.0|1864|mmu:192166|sarcosine dehydrogenase [EC:1.5.8.3] GO:0044429 GO:0046997;GO:0000166//nucleotide binding;GO:0008168//methyltransferase activity GO:0006544//glycine metabolic process;GO:0019695//choline metabolic process "gi|20149748|ref|NP_619606.1|/0/sarcosine dehydrogenase, mitochondrial [Mus musculus]" 207958 4970 1.503333333 1.883333333 0.325123434 Up 0.275912972 Alg11 "asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)" "K03844|1|0.0|781|mmu:207958|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0000026//alpha-1,2-mannosyltransferase activity" GO:0006487//protein N-linked glycosylation "gi|341926298|ref|NP_001230090.1|/0/GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase isoform 1 [Mus musculus]" 22771 3350 0.926666667 0.64 -0.533978572 Down 0.275875362 Zic1 zinc finger protein of the cerebellum 1 K09224|1|0.0|724|cjc:100407505|zinc finger protein ZIC 1 GO:0031981//nuclear lumen GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding "GO:0006351//transcription, DNA-templated;GO:0007417//central nervous system development;GO:0007224//smoothened signaling pathway;GO:0042471//ear morphogenesis;GO:0006606//protein import into nucleus" gi|675738990|ref|XP_002807704.2|/0/PREDICTED: LOW QUALITY PROTEIN: zinc finger protein ZIC 1 [Callithrix jacchus] 232790 1830 0.406666667 0.196666667 -1.048094288 Down 0.275818948 Oscar osteoclast associated receptor K14377|1|6e-153|543|mmu:232790|osteoclast-associated immunoglobulin-like receptor GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148699235|gb|EDL31182.1|/1.04419e-163/osteoclast associated receptor, isoform CRA_a, partial [Mus musculus]" 98878 3387 194.33 181.7033333 -0.09692375 Down 0.275800143 Ehd4 EH-domain containing 4 K12477|1|0.0|1053|mmu:98878|EH domain-containing protein 4 GO:0010008//endosome membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0046872//metal ion binding GO:0070848//response to growth factor;GO:0001934//positive regulation of protein phosphorylation;GO:0051259//protein oligomerization;GO:0006897//endocytosis;GO:0009154//purine ribonucleotide catabolic process gi|31981592|ref|NP_598599.2|/0/EH domain-containing protein 4 [Mus musculus] 67397 1258 35.16666667 38.07666667 0.114698594 Up 0.275790741 Erp29 endoplasmic reticulum protein 29 K09586|1|7e-131|469|mmu:67397|endoplasmic reticulum protein 29 GO:0044432;GO:0048770 "GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups" GO:0050896//response to stimulus;GO:0044267//cellular protein metabolic process;GO:0015031//protein transport gi|19526463|ref|NP_080405.1|/5.88938e-130/endoplasmic reticulum resident protein 29 precursor [Mus musculus] 67088 5453 40.14333333 37.23 -0.108694801 Down 0.275790741 Cand2 cullin-associated and neddylation-dissociated 2 (putative) K17263|1|0.0|1519|mdo:100015450|cullin-associated NEDD8-dissociated protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0008134//transcription factor binding "GO:0006351//transcription, DNA-templated" gi|37360036|dbj|BAC97996.1|/0/mKIAA0667 protein [Mus musculus] 56696 2439 0.083333333 0.266666667 1.678071905 Up 0.275734326 Gpr132 G protein-coupled receptor 132 K08426|1|0.0|705|mmu:56696|G protein-coupled receptor 132 GO:0016021//integral component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|9910232|ref|NP_064309.1|/0/probable G-protein coupled receptor 132 [Mus musculus] 80876 646 166.69 179.0966667 0.103570929 Up 0.275734326 Ifitm2 interferon induced transmembrane protein 2 K06566|1|1e-76|287|xla:100037081|interferon induced transmembrane protein GO:0031224//intrinsic component of membrane;GO:0005770//late endosome - GO:0019079//viral genome replication;GO:0046718//viral entry into host cell;GO:0006952//defense response;GO:0051707//response to other organism;GO:0019221//cytokine-mediated signaling pathway;GO:0002252;GO:0008283//cell proliferation gi|13507626|ref|NP_109619.1|/9.40801e-76/interferon-induced transmembrane protein 2 [Mus musculus] 224613 2509 14.93666667 13.67 -0.127844983 Down 0.27566851 Flywch1 FLYWCH-type zinc finger 1 "K06237|1|1e-07|61.2|fab:101814446|collagen, type IV, alpha" - - - gi|255003742|ref|NP_722486.2|/0/FLYWCH-type zinc finger-containing protein 1 [Mus musculus] 242736 3882 2.646666667 3.123333333 0.238910041 Up 0.275659107 Pramef8 PRAME family member 8 K10308|1|1e-15|88.6|myb:102259491|F-box protein 31 - - - gi|27370334|ref|NP_766465.1|/0/PRAME family member 8 [Mus musculus] 54393 4486 3.186666667 2.706666667 -0.235530891 Down 0.275659107 Gabbr1 "gamma-aminobutyric acid (GABA) B receptor, 1" K04615|1|0.0|1640|mmu:54393|gamma-aminobutyric acid type B receptor GO:0031090//organelle membrane;GO:0032589//neuron projection membrane;GO:0005740//mitochondrial envelope;GO:0043235//receptor complex;GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle;GO:0030425//dendrite;GO:0044297//cell body;GO:0044421;GO:0097060//synaptic membrane GO:0004930//G-protein coupled receptor activity;GO:0005515//protein binding GO:0014046;GO:0007268//chemical synaptic transmission;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0030252//growth hormone secretion;GO:0014070//response to organic cyclic compound;GO:0014051//gamma-aminobutyric acid secretion;GO:0014047//glutamate secretion;GO:0010646//regulation of cell communication;GO:0014060;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0097305//response to alcohol gi|131888529|ref|NP_062312.3|/0/gamma-aminobutyric acid type B receptor subunit 1 precursor [Mus musculus] 68977 1306.66 6.586666667 5.853333333 -0.170290102 Down 0.275536876 Haghl hydroxyacylglutathione hydrolase-like K01069|1|1e-164|582|mmu:68977|hydroxyacylglutathione hydrolase [EC:3.1.2.6] - GO:0046914//transition metal ion binding;GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding;GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding;GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding;GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding;GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding;GO:0016790//thiolester hydrolase activity GO:0006749//glutathione metabolic process;GO:0006749//glutathione metabolic process;GO:0006749//glutathione metabolic process;GO:0006749//glutathione metabolic process;GO:0006749//glutathione metabolic process;GO:0006749//glutathione metabolic process gi|21312167|ref|NP_081173.1|/3.65695e-144/hydroxyacylglutathione hydrolase-like protein isoform a [Mus musculus] 231386 3034 10.34333333 11.39333333 0.1394887 Up 0.275480462 Ythdc1 YTH domain containing 1 K20100|1|0.0|1003|mmu:231386|YTH domain-containing protein 1 - - - gi|124430549|ref|NP_808348.2|/0/YTH domain-containing protein 1 [Mus musculus] 503550 838 0.133333333 0.01 -3.736965594 Down 0.275471059 Klri1 killer cell lectin-like receptor family I member 1 K06541|1|2e-20|101|cge:100774220|killer cell lectin-like receptor subfamily C - - - gi|568942370|ref|XP_006506426.1|/2.23824e-149/PREDICTED: killer cell lectin-like receptor family I member 1 isoform X1 [Mus musculus] 14945 792 0.01 0.133333333 3.736965594 Up 0.275471059 Gzmk granzyme K K08663|1|3e-154|546|mmu:14945|granzyme K [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|6680143|ref|NP_032222.1|/2.30374e-153/granzyme K precursor [Mus musculus] 83984 1358 0.01 0.133333333 3.736965594 Up 0.275471059 Tssk6 testis-specific serine kinase 6 K08811|1|4e-156|553|mmu:83984|testis-specific serine kinase [EC:2.7.11.1] - - - - 69050 417 0.13 0.01 -3.700439718 Down 0.275471059 1810013A23Rik RIKEN cDNA 1810013A23 gene - - - - - 75555 1087 0.01 0.133333333 3.736965594 Up 0.275471059 1700020D05Rik RIKEN cDNA 1700020D05 gene K12464|1|2e-39|165|hgl:101702796|melanoma-associated antigen D1 - - - gi|268607534|ref|NP_076270.3|/2.25699e-164/mage-g2 protein [Mus musculus] 55938 731 0.01 0.13 3.700439718 Up 0.275471059 Apom apolipoprotein M - GO:0034385;GO:0034364//high-density lipoprotein particle GO:0022892//substrate-specific transporter activity;GO:0008289//lipid binding GO:0009746;GO:0030301//cholesterol transport;GO:0034377//plasma lipoprotein particle assembly;GO:0034441//plasma lipoprotein particle oxidation;GO:0034381//plasma lipoprotein particle clearance;GO:0034369//plasma lipoprotein particle remodeling gi|9055162|ref|NP_061286.1|/2.4831e-108/apolipoprotein M precursor [Mus musculus] 100042149 2139 0.01 0.13 3.700439718 Up 0.275471059 Gm3696 predicted gene 3696 "K03844|1|3e-16|89.7|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - - 22626 2077 0.01 0.133333333 3.736965594 Up 0.275471059 Slc23a3 "solute carrier family 23 (nucleobase transporters), member 3" "K14612|1|0.0|1042|mmu:22626|solute carrier family 23 (nucleobase transporter), member 3" GO:0044424;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763 "gi|148667947|gb|EDL00364.1|/0/solute carrier family 23 (nucleobase transporters), member 3, partial [Mus musculus]" 13012 703 0.01 0.133333333 3.736965594 Up 0.275471059 Cst8 cystatin 8 (cystatin-related epididymal spermatogenic) K13904|1|8e-78|291|mmu:13012|cystatin-8 GO:0044424 GO:0004857//enzyme inhibitor activity GO:0051346//negative regulation of hydrolase activity gi|33468891|ref|NP_034108.1|/6.10903e-77/cystatin-8 precursor [Mus musculus] 22352 1834 175.0466667 163.3266667 -0.099979228 Down 0.275405243 Vim vimentin K07606|1|0.0|748|mmu:22352|vimentin GO:0043005//neuron projection;GO:0016020//membrane;GO:0034399//nuclear periphery;GO:0042579//microbody;GO:0031988//membrane-bounded vesicle;GO:0005882//intermediate filament GO:0005198//structural molecule activity;GO:0019903//protein phosphatase binding;GO:0019900//kinase binding GO:0071363//cellular response to growth factor stimulus;GO:0042246//tissue regeneration;GO:0007409//axonogenesis;GO:0010975//regulation of neuron projection development;GO:0043627//response to estrogen;GO:0045104//intermediate filament cytoskeleton organization;GO:0008284//positive regulation of cell proliferation;GO:0001893//maternal placenta development;GO:0010038//response to metal ion;GO:0009628//response to abiotic stimulus;GO:0014013//regulation of gliogenesis;GO:0021782//glial cell development;GO:0048708//astrocyte differentiation gi|31982755|ref|NP_035831.2|/0/vimentin [Mus musculus] 67177 2245 0.736666667 1.033333333 0.488221846 Up 0.275377036 Cdt1 chromatin licensing and DNA replication factor 1 K10727|1|0.0|855|mmu:67177|chromatin licensing and DNA replication factor 1 GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding GO:0000084//mitotic S phase;GO:0031570//DNA integrity checkpoint;GO:0006270//DNA replication initiation;GO:0000082//G1/S transition of mitotic cell cycle gi|31982546|ref|NP_080290.3|/0/DNA replication factor Cdt1 [Mus musculus] 242297 1995 2.896666667 3.396666667 0.229725969 Up 0.275320621 Fam110b "family with sequence similarity 110, member B" - GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle - - "gi|148673748|gb|EDL05695.1|/0/RIKEN cDNA 1700012H17, isoform CRA_c, partial [Mus musculus]" 433408 1385 37.15333333 39.98333333 0.105907099 Up 0.275320621 Gm13375 predicted gene 13375 - - - - - 21341 3255 2.903333333 3.403333333 0.229238242 Up 0.275320621 Taf1c "TATA-box binding protein associated factor, RNA polymerase I, C" K15214|1|0.0|1535|mmu:21341|TATA box-binding protein-associated factor RNA polymerase I subunit C GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|133778985|ref|NP_067416.2|/0/TATA box-binding protein-associated factor RNA polymerase I subunit C [Mus musculus] 12385 3713 154.9166667 166.3433333 0.102671683 Up 0.275273609 Ctnna1 "catenin (cadherin associated protein), alpha 1" K05691|1|0.0|1659|mmu:12385|catenin alpha GO:0044291//cell-cell contact zone;GO:0030141//secretory granule;GO:0005913//cell-cell adherens junction;GO:0019897//extrinsic component of plasma membrane;GO:0031252//cell leading edge;GO:0005856//cytoskeleton GO:0050839//cell adhesion molecule binding;GO:0003779//actin binding GO:0007043//cell-cell junction assembly;GO:0007409//axonogenesis;GO:0071407//cellular response to organic cyclic compound;GO:0042476//odontogenesis;GO:0008585//female gonad development;GO:0007405//neuroblast proliferation;GO:0006915//apoptotic process;GO:0048545//response to steroid hormone;GO:0022610;GO:0051259//protein oligomerization;GO:0007224//smoothened signaling pathway;GO:0042692//muscle cell differentiation "gi|485602209|pdb|4K1N|A/0/Chain A, Crystal Structure Of Full-length Mouse Alphae-catenin" 225131 5151.78 14.29 13.03333333 -0.13279981 Down 0.27519839 Wac WW domain containing adaptor with coiled-coil - GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0001099//basal RNA polymerase II transcription machinery binding;GO:0001099//basal RNA polymerase II transcription machinery binding "GO:0006351//transcription, DNA-templated;GO:0010508//positive regulation of autophagy;GO:0006513//protein monoubiquitination;GO:0031330;GO:0033523//histone H2B ubiquitination;GO:0033554//cellular response to stress;GO:0006351//transcription, DNA-templated;GO:0010508//positive regulation of autophagy;GO:0006513//protein monoubiquitination;GO:0031330;GO:0033523//histone H2B ubiquitination;GO:0033554//cellular response to stress" gi|226371675|ref|NP_694725.3|/0/WW domain-containing adapter protein with coiled-coil isoform 1 [Mus musculus] 381199 4007 0.423333333 0.21 -1.011404763 Down 0.27519839 Tmem151a transmembrane protein 151A K06757|1|0.0|783|chx:102181063|neurofascin GO:0031224//intrinsic component of membrane - - gi|49457865|ref|NP_001001885.1|/0/transmembrane protein 151A [Mus musculus] 72759 3693 13.47666667 14.74 0.129272822 Up 0.27519839 Tmem135 transmembrane protein 135 - - - - gi|228008286|ref|NP_082619.3|/0/transmembrane protein 135 [Mus musculus] 12017 1365 148.7966667 159.9933333 0.104669584 Up 0.27519839 Bag1 BCL2-associated athanogene 1 K09555|1|4e-144|513|mmu:12017|BCL2-associated athanogene 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0005515//protein binding GO:0042026//protein refolding;GO:0010038//response to metal ion;GO:0043065//positive regulation of apoptotic process;GO:0014070//response to organic cyclic compound;GO:0030154//cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0042026//protein refolding;GO:0010038//response to metal ion;GO:0043065//positive regulation of apoptotic process;GO:0014070//response to organic cyclic compound;GO:0030154//cell differentiation;GO:0006366//transcription from RNA polymerase II promoter gi|157952206|ref|NP_033866.4|/3.08215e-143/BAG family molecular chaperone regulator 1 isoform 1L [Mus musculus] 225908 5613 1.746666667 1.376666667 -0.34342503 Down 0.275188988 Myrf myelin regulatory factor K16673|1|3e-27|127|chx:106501930|LIX1-like protein - - - gi|242247266|ref|NP_001028653.1|/0/myelin regulatory factor [Mus musculus] 76814 316 0.353333333 0.153333333 -1.204358499 Down 0.275160781 Scarletltr "Scarletltr, erythroid developmental long intergenic non-protein coding transcript" - - - - - 74868 3644 37.93666667 35.13333333 -0.11075246 Down 0.275151378 Tmem65 transmembrane protein 65 K01183|1|1e-25|122|dgr:Dgri_GH10759|chitinase [EC:3.2.1.14];K04257|2|2e-19|101|rno:688691|olfactory receptor GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|70778812|ref|NP_780421.2|/1.60635e-111/transmembrane protein 65 [Mus musculus] 11966 2742 34.76333333 37.56333333 0.111758668 Up 0.275151378 Atp6v1b2 "ATPase, H+ transporting, lysosomal V1 subunit B2" K02147|1|0.0|1033|ngi:103747668|V-type H+-transporting ATPase subunit B GO:0031224//intrinsic component of membrane;GO:0033176//proton-transporting V-type ATPase complex;GO:0042995//cell projection;GO:0048770 GO:0022857//transmembrane transporter activity;GO:0003824//catalytic activity "GO:0051452//intracellular pH reduction;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0009150//purine ribonucleotide metabolic process" "gi|532056467|ref|XP_005370941.1|/0/PREDICTED: V-type proton ATPase subunit B, brain isoform [Microtus ochrogaster]" 100043424 815.94 2.863333333 2.406666667 -0.250659294 Down 0.275132574 Gm14005 predicted gene 14005 - - - - - 214804 5495 2.73 2.286666667 -0.255654875 Down 0.275123171 Syde2 "synapse defective 1, Rho GTPase, homolog 2 (C. elegans)" K08878|1|7e-34|149|tru:101073705|breakpoint cluster region protein [EC:2.7.11.1] - - - gi|755503640|ref|XP_006501355.2|/0/PREDICTED: rho GTPase-activating protein SYDE2 isoform X1 [Mus musculus] 545091 1165 0.3 0.11 -1.447458977 Down 0.275085562 Gm5803 predicted gene 5803 K12741|1|4e-108|393|mmu:545091|heterogeneous nuclear ribonucleoprotein A1/A3 GO:0005681//spliceosomal complex;GO:0005856//cytoskeleton;GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0036094//small molecule binding;GO:0043566//structure-specific DNA binding "GO:0050658//RNA transport;GO:0000398//mRNA splicing, via spliceosome;GO:0006913//nucleocytoplasmic transport" "gi|148671985|gb|EDL03932.1|/5.48726e-111/mCG15678, isoform CRA_c, partial [Mus musculus]" 66940 1891.47 35.38 38.17 0.109505139 Up 0.275066757 Shisa5 shisa family member 5 K10135|1|1e-12|77.0|mmu:66940|scotin GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system - GO:0012502//induction of programmed cell death;GO:0012502//induction of programmed cell death;GO:0044763 gi|194385126|dbj|BAG60969.1|/1.16884e-30/unnamed protein product [Homo sapiens] 69895 785 3.623333333 3.106666667 -0.22195008 Down 0.275057355 Snhg8 small nucleolar RNA host gene 8 - - - - "gi|149025889|gb|EDL82132.1|/8.31864e-15/rCG28667, isoform CRA_b [Rattus norvegicus]" 13163 2598 9.996666667 11.03333333 0.142349695 Up 0.275010343 Daxx Fas death domain-associated protein K02308|1|0.0|772|mmu:13163|death-associated protein 6 GO:0000785//chromatin;GO:0016604//nuclear body;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0000785//chromatin;GO:0016604//nuclear body;GO:0042995//cell projection;GO:0044444//cytoplasmic part GO:0044389//ubiquitin-like protein ligase binding;GO:0003712//transcription cofactor activity;GO:0042802//identical protein binding;GO:0035258//steroid hormone receptor binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003712//transcription cofactor activity;GO:0042802//identical protein binding;GO:0035258//steroid hormone receptor binding "GO:0006351//transcription, DNA-templated;GO:0016567//protein ubiquitination;GO:0012502//induction of programmed cell death;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0016567//protein ubiquitination;GO:0012502//induction of programmed cell death;GO:0030518//intracellular steroid hormone receptor signaling pathway" gi|74145060|dbj|BAE27403.1|/0/unnamed protein product [Mus musculus] 66199 824 10.53666667 11.57666667 0.135801375 Up 0.275010343 Commd4 COMM domain containing 4 - GO:0044424 GO:0005488//binding - gi|13384806|ref|NP_079693.1|/1.2424e-96/COMM domain-containing protein 4 [Mus musculus] 52276 1626 0.58 0.86 0.56828376 Up 0.275010343 Cdca8 cell division cycle associated 8 K11514|1|3e-136|488|mmu:52276|Borealin GO:0044427;GO:0005875//microtubule associated complex;GO:0005816//spindle pole body;GO:0031981//nuclear lumen - GO:0007067//mitotic nuclear division "gi|148698395|gb|EDL30342.1|/1.87024e-153/cell division cycle associated 8, isoform CRA_c, partial [Mus musculus]" 74476 2179.31 1.186666667 1.536666667 0.372889509 Up 0.274972733 4933439C10Rik RIKEN cDNA 4933439C10 gene - - - - gi|74146726|dbj|BAE41348.1|/5.52498e-70/unnamed protein product [Mus musculus] 75964 5178 5.61 4.943333333 -0.182516579 Down 0.274963331 Trappc8 trafficking protein particle complex 8 K20305|1|0.0|2722|rno:291750|trafficking protein particle complex subunit 8 - - - gi|119964702|ref|NP_083767.2|/0/trafficking protein particle complex subunit 8 isoform 2 [Mus musculus] 71985 3621 1.726666667 2.13 0.302863833 Up 0.274869307 Acad10 "acyl-Coenzyme A dehydrogenase family, member 10" K11729|1|0.0|2156|mmu:71985|acyl-CoA dehydrogenase family member 10 GO:0043231//intracellular membrane-bounded organelle GO:0016491//oxidoreductase activity;GO:0000166//nucleotide binding;GO:0016740//transferase activity GO:0044710 gi|156255157|ref|NP_082313.2|/0/acyl-CoA dehydrogenase family member 10 [Mus musculus] 11684 2991 2.1 1.7 -0.304854582 Down 0.274869307 Alox12 arachidonate 12-lipoxygenase K00458|1|0.0|1304|mmu:11684|arachidonate 12-lipoxygenase [EC:1.13.11.31] GO:0005886//plasma membrane;GO:0044444//cytoplasmic part "GO:0046914//transition metal ion binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" GO:0010594//regulation of endothelial cell migration;GO:0032846;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0007155//cell adhesion;GO:0010467//gene expression;GO:0006915//apoptotic process;GO:0030858//positive regulation of epithelial cell differentiation;GO:0042311//vasodilation;GO:0006690//icosanoid metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0016049//cell growth "gi|31542127|ref|NP_031466.2|/0/arachidonate 12-lipoxygenase, 12S-type [Mus musculus]" 751865 1079 1.686666667 2.083333333 0.304718805 Up 0.274869307 Sap25 sin3 associated polypeptide K19193|1|2e-151|537|mmu:751865|histone deacetylase complex subunit SAP25 GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated" gi|274326266|ref|NP_001075431.2|/1.40081e-150/histone deacetylase complex subunit SAP25 [Mus musculus] 193838 1521 4.313333333 4.93 0.192784435 Up 0.274831697 Eme2 essential meiotic structure-specific endonuclease subunit 2 K10883|1|0.0|645|mmu:193838|crossover junction endonuclease EME2 - - - - 22030 3044 4.3 4.916666667 0.193343889 Up 0.274831697 Traf2 TNF receptor-associated factor 2 K03173|1|0.0|979|mmu:22030|TNF receptor-associated factor 2 [EC:2.3.2.27] GO:0032991//macromolecular complex;GO:0005887//integral component of plasma membrane;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0005887//integral component of plasma membrane;GO:0044444//cytoplasmic part GO:0008289//lipid binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0019901//protein kinase binding;GO:0046914//transition metal ion binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0008289//lipid binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0019901//protein kinase binding;GO:0046914//transition metal ion binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0044389//ubiquitin-like protein ligase binding GO:0009057//macromolecule catabolic process;GO:0032092//positive regulation of protein binding;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002637//regulation of immunoglobulin production;GO:0032147//activation of protein kinase activity;GO:0043406//positive regulation of MAP kinase activity;GO:0019221//cytokine-mediated signaling pathway;GO:0051260//protein homooligomerization;GO:0007254//JNK cascade;GO:0001819//positive regulation of cytokine production;GO:0097191//extrinsic apoptotic signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0000209//protein polyubiquitination;GO:0009057//macromolecule catabolic process;GO:0032092//positive regulation of protein binding;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002637//regulation of immunoglobulin production;GO:0032147//activation of protein kinase activity;GO:0043406//positive regulation of MAP kinase activity;GO:0019221//cytokine-mediated signaling pathway;GO:0051260//protein homooligomerization;GO:0007254//JNK cascade;GO:0001819//positive regulation of cytokine production;GO:0097191//extrinsic apoptotic signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0000209//protein polyubiquitination gi|83921633|ref|NP_033448.2|/0/TNF receptor-associated factor 2 isoform b [Mus musculus] 20723 3397 4.49 5.106666667 0.185666446 Up 0.274831697 Serpinb9 "serine (or cysteine) peptidase inhibitor, clade B, member 9" K13963|1|0.0|748|mmu:20723|serpin B - - - "gi|6678101|ref|NP_033282.1|/0/serine (or cysteine) proteinase inhibitor, clade B, member 9 [Mus musculus]" 22590 972 4.516666667 5.136666667 0.18557401 Up 0.274831697 Xpa "xeroderma pigmentosum, complementation group A" K10847|1|5e-129|462|mmu:22590|DNA-repair protein complementing XP-A cells GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0042802//identical protein binding;GO:0003677//DNA binding GO:0006281//DNA repair;GO:0009416//response to light stimulus;GO:0040007//growth;GO:0042221//response to chemical gi|239937475|ref|NP_035858.2|/3.6843e-128/DNA repair protein complementing XP-A cells homolog [Mus musculus] 74183 3849 153.6866667 143.2233333 -0.101725458 Down 0.27480349 Perm1 "PPARGC1 and ESRR induced regulator, muscle 1" K10955|1|1e-08|65.5|asn:102388355|intestinal mucin-2;K11661|2|1e-07|62.4|mze:101463686|helicase SRCAP [EC:3.6.4.-];K10431|3|2e-07|61.6|tgu:100222640|microtubule-associated protein 4;K04989|4|5e-07|60.1|rno:100362565|polycystin 1L3 - - - gi|161377418|ref|NP_766005.2|/0/PGC-1 and ERR-induced regulator in muscle protein 1 [Mus musculus] 69029 608 140.0733333 150.4666667 0.103261591 Up 0.274765881 Smdt1 single-pass membrane protein with aspartate rich tail 1 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - "gi|564309079|ref|XP_003754371.2|/2.50424e-53/PREDICTED: essential MCU regulator, mitochondrial [Rattus norvegicus]" 664862 2956 1.956666667 2.373333333 0.278516738 Up 0.274700064 Gpr137b-ps "G protein-coupled receptor 137B, pseudogene" - GO:0005764//lysosome;GO:0016021//integral component of membrane - - gi|8132351|gb|AAF73259.1|AF154337_1/0/putative seven pass transmembrane protein [Mus musculus] 72282 911 0.163333333 0.366666667 1.166649869 Up 0.274521419 1810062G17Rik RIKEN cDNA 1810062G17 gene - - - - gi|332205857|ref|NP_082459.1|/1.78603e-65/uncharacterized protein LOC72282 [Mus musculus] 67337 1820 13.31 14.54666667 0.12817803 Up 0.274436797 Cstf1 "cleavage stimulation factor, 3' pre-RNA, subunit 1" K14406|1|0.0|890|aml:100469343|cleavage stimulation factor subunit 1 GO:0043231//intracellular membrane-bounded organelle - GO:0006396//RNA processing gi|752410156|ref|XP_002921256.2|/0/PREDICTED: cleavage stimulation factor subunit 1 isoform X1 [Ailuropoda melanoleuca] 66868 2978 6.693333333 7.496666667 0.163524392 Up 0.27437098 Mfsd1 major facilitator superfamily domain containing 1 "K11131|1|3e-121|439|aqu:100641334|H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-];K19801|2|1e-83|314|tsp:Tsp_08498|phosphatidylinositol 4-kinase B [EC:2.7.1.67];K08220|3|2e-06|57.4|nvi:100120856|MFS transporter, FLVCR family, feline leukemia virus subgroup C receptor-related protein" - - - - 98415 6096 6.663333333 7.46 0.162931564 Up 0.27437098 Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 - - - - "gi|148707748|gb|EDL39695.1|/5.4082e-38/nuclear casein kinase and cyclin-dependent kinase substrate 1, isoform CRA_b, partial [Mus musculus]" 103220 3434.33 0.45 0.706666667 0.651104858 Up 0.27437098 Ttc41 tetratricopeptide repeat domain 41 K19360|1|3e-08|63.2|crg:105326231|nephrocystin-3 GO:0044424;GO:0044424;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - - gi|145966705|ref|NP_705823.3|/0/tetratricopeptide repeat protein 41 isoform 2 [Mus musculus] 15130 630 7.416666667 6.62 -0.163939713 Down 0.27437098 Hbb-b2 "hemoglobin, beta adult minor chain" K13823|1|2e-80|300|mmu:15130|hemoglobin subunit beta GO:0043234//protein complex GO:0046906//tetrapyrrole binding;GO:0022892//substrate-specific transporter activity;GO:0046914//transition metal ion binding GO:0001932//regulation of protein phosphorylation;GO:0015669;GO:0030218//erythrocyte differentiation gi|17647499|ref|NP_058652.1|/1.33508e-79/hemoglobin subunit beta-2 [Mus musculus] 15247 2795 6.99 7.793333333 0.156948068 Up 0.27437098 Mfsd14a major facilitator superfamily domain containing 14A "K14613|1|1e-06|58.2|der:Dere_GG23423|MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1/3" GO:0031224//intrinsic component of membrane - GO:0044765//single-organism transport;GO:0044763 gi|537271325|gb|ERE92038.1|/0/hippocampus abundant transcript 1 protein [Cricetulus griseus] 23954 2044 1.293333333 1.653333333 0.354283468 Up 0.274333371 Nek3 NIMA (never in mitosis gene a)-related expressed kinase 3 K08857|1|0.0|971|mmu:23954|NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] - - - "gi|148700958|gb|EDL32905.1|/0/NIMA (never in mitosis gene a)-related expressed kinase 3, isoform CRA_a, partial [Mus musculus]" 56226 2130.08 1.29 1.646666667 0.352177475 Up 0.274333371 Espn espin - GO:0032421//stereocilium bundle;GO:0005884//actin filament;GO:0005902//microvillus;GO:0032421//stereocilium bundle;GO:0042995//cell projection;GO:0005884//actin filament;GO:0032421//stereocilium bundle;GO:0042995//cell projection;GO:0005884//actin filament;GO:0032421//stereocilium bundle;GO:0042995//cell projection;GO:0044446;GO:0015629//actin cytoskeleton;GO:0005856//cytoskeleton;GO:0032421//stereocilium bundle;GO:0042995//cell projection;GO:0032421//stereocilium bundle;GO:0005884//actin filament;GO:0005902//microvillus GO:0003779//actin binding;GO:0019904//protein domain specific binding;GO:0003779//actin binding;GO:0019904//protein domain specific binding;GO:0003779//actin binding;GO:0019904//protein domain specific binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0003779//actin binding;GO:0019904//protein domain specific binding GO:0031346//positive regulation of cell projection organization;GO:0051017//actin filament bundle assembly;GO:0044708//single-organism behavior;GO:0051017//actin filament bundle assembly;GO:0051128//regulation of cellular component organization;GO:0051017//actin filament bundle assembly;GO:0051128//regulation of cellular component organization;GO:0031346//positive regulation of cell projection organization;GO:0051017//actin filament bundle assembly;GO:0044708//single-organism behavior;GO:0031346//positive regulation of cell projection organization;GO:0051017//actin filament bundle assembly;GO:0044708//single-organism behavior;GO:0031346//positive regulation of cell projection organization;GO:0051017//actin filament bundle assembly;GO:0044708//single-organism behavior gi|46877084|ref|NP_062531.2|/1.56883e-91/espin isoform 6 [Mus musculus] 57261 5646.91 21.09 19.42666667 -0.118520718 Down 0.274314566 Brd4 bromodomain containing 4 K11722|1|0.0|704|cge:100771403|bromodomain-containing protein 4 GO:0000785//chromatin;GO:0000228//nuclear chromosome;GO:0000785//chromatin;GO:0000228//nuclear chromosome GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0043967//histone H4 acetylation;GO:0051099//positive regulation of binding;GO:0043966//histone H3 acetylation;GO:0001832//blastocyst growth;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0000086//G2/M transition of mitotic cell cycle;GO:0043967//histone H4 acetylation;GO:0051099//positive regulation of binding;GO:0043966//histone H3 acetylation;GO:0001832//blastocyst growth;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0000086//G2/M transition of mitotic cell cycle "gi|148708381|gb|EDL40328.1|/0/bromodomain containing 4, isoform CRA_c, partial [Mus musculus]" 66514 2274 21.35333333 19.69 -0.116998186 Down 0.274314566 Asrgl1 asparaginase like 1 K13051|1|7e-170|600|mmu:66514|beta-aspartyl-peptidase (threonine type) [EC:3.4.19.5] GO:0005856//cytoskeleton;GO:0031981//nuclear lumen "GO:0008242//omega peptidase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0006530//asparagine catabolic process;GO:0019538//protein metabolic process gi|31560239|ref|NP_079886.2|/6.34754e-169/isoaspartyl peptidase/L-asparaginase [Mus musculus] 16633 1886 0.113333333 0.3 1.404390255 Up 0.27421114 Klra2 "killer cell lectin-like receptor, subfamily A, member 2" K17515|1|2e-14|83.2|cmy:102931345|C-type lectin domain family 9 member A;K17517|2|1e-12|77.8|myb:102251819|C-type lectin domain family 12 member B;K17516|3|1e-12|77.4|mcf:102143884|C-type lectin domain family 12 member A GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding GO:0022610;GO:0022610 gi|568940875|ref|XP_006505705.1|/3.46375e-180/PREDICTED: killer cell lectin-like receptor 2 isoform X1 [Mus musculus] 237339 3411 1.913333333 1.536666667 -0.316283986 Down 0.274192335 L3mbtl3 l(3)mbt-like 3 (Drosophila) K11465|1|5e-42|176|tup:102500909|sex comb on midleg-like protein 2;K11461|4|9e-42|175|dya:Dyak_GE24755|polycomb protein SCMH1 GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" gi|27370170|ref|NP_766375.1|/0/lethal(3)malignant brain tumor-like protein 3 [Mus musculus] 66628 3797 1.52 1.903333333 0.324456921 Up 0.274192335 Thg1l tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) K10761|1|1e-135|487|mmu:66628|tRNA(His) guanylyltransferase [EC:2.7.7.79] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0008192//RNA guanylyltransferase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0032550;GO:0008192//RNA guanylyltransferase activity;GO:0046872//metal ion binding;GO:0005515//protein binding GO:0051260//protein homooligomerization;GO:0008033//tRNA processing;GO:0051260//protein homooligomerization;GO:0008033//tRNA processing gi|595582307|ref|NP_001277666.1|/2.53535e-136/probable tRNA(His) guanylyltransferase isoform 2 [Mus musculus] 414077 815 34.75 37.41333333 0.10653953 Up 0.274154726 Wdr83os WD repeat domain 83 opposite strand - GO:0031224//intrinsic component of membrane - - "gi|148679052|gb|EDL10999.1|/1.32329e-66/cDNA sequence BC056474, partial [Mus musculus]" 81913 1215 3.953333333 4.536666667 0.198563057 Up 0.274126518 Bambi-ps1 "BMP and activin membrane-bound inhibitor, pseudogene (Xenopus laevis)" K10162|1|2e-70|172|ocu:100356824|BMP and activin membrane-bound inhibitor - - - gi|655858787|ref|XP_008266253.1|/1.65177e-69/PREDICTED: BMP and activin membrane-bound inhibitor homolog [Oryctolagus cuniculus] 13079 1939 3.9 4.483333333 0.201097643 Up 0.274126518 Cyp21a1 "cytochrome P450, family 21, subfamily a, polypeptide 1" K00513|1|0.0|934|mmu:13079|steroid 21-monooxygenase [EC:1.14.14.16] GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0008289//lipid binding;GO:0008395//steroid hydroxylase activity GO:0009636//response to toxic substance;GO:0032870//cellular response to hormone stimulus;GO:0006694//steroid biosynthetic process;GO:0008207//C21-steroid hormone metabolic process gi|74138930|dbj|BAE27263.1|/0/unnamed protein product [Mus musculus] 321006 5392 4.496666667 3.913333333 -0.20045794 Down 0.274126518 Vprbp Vpr (HIV-1) binding protein K11789|1|0.0|2642|mmu:321006|HIV-1 Vpr-binding protein GO:0044424 - - gi|82617569|ref|NP_001015507.1|/0/protein VPRBP [Mus musculus] 12029 3426 9.193333333 8.306666667 -0.146318388 Down 0.274070104 Bcl6b "B cell CLL/lymphoma 6, member B" K15618|1|5e-91|338|lcm:102350689|B-cell lymphoma 6 protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0006366//transcription from RNA polymerase II promoter gi|6671616|ref|NP_031554.1|/0/B-cell CLL/lymphoma 6 member B protein [Mus musculus] 14389 6007.48 8.996666667 8.103333333 -0.150875083 Down 0.274070104 Gab2 growth factor receptor bound protein 2-associated protein 2 K08091|1|0.0|1321|mmu:14389|growth factor receptor bound protein 2-associated protein 2 GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part;GO:0016020//membrane "GO:0030674//protein binding, bridging;GO:0043168//anion binding;GO:0008289//lipid binding;GO:0030674//protein binding, bridging;GO:0043168//anion binding;GO:0008289//lipid binding" GO:0048870//cell motility;GO:0002573//myeloid leukocyte differentiation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0048017//inositol lipid-mediated signaling;GO:0033008;GO:0008283//cell proliferation;GO:0048870//cell motility;GO:0002573//myeloid leukocyte differentiation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0048017//inositol lipid-mediated signaling;GO:0033008;GO:0008283//cell proliferation gi|247270076|ref|NP_001155949.1|/0/GRB2-associated-binding protein 2 isoform 2 [Mus musculus] 109115 1483 13.01666667 14.24333333 0.129926769 Up 0.274032495 Supt3 suppressor of Ty 3 K11313|1|3e-174|613|mmu:109115|transcription initiation protein SPT3 GO:0070461//SAGA-type complex;GO:0005667//transcription factor complex - GO:0016573//histone acetylation gi|568998626|ref|XP_006523540.1|/0/PREDICTED: transcription initiation protein SPT3 homolog isoform X4 [Mus musculus] 20200 719 20.72333333 19.07666667 -0.119446972 Down 0.273994885 S100a6 S100 calcium binding protein A6 (calcyclin) - GO:0043231//intracellular membrane-bounded organelle;GO:0009898//cytoplasmic side of plasma membrane;GO:0031252//cell leading edge;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0022891//substrate-specific transmembrane transporter activity;GO:0042802//identical protein binding GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006811//ion transport;GO:0008284//positive regulation of cell proliferation;GO:0007154//cell communication gi|674037254|ref|XP_008853760.1|/7.32627e-41/PREDICTED: protein S100-A6 [Nannospalax galili] 17749 523.77 20.14 18.49 -0.123318459 Down 0.273994885 Polr2k polymerase (RNA) II (DNA directed) polypeptide K "K03009|1|6e-29|128|oas:101104250|DNA-directed RNA polymerases I, II, and III subunit RPABC4" GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity GO:0006383//transcription from RNA polymerase III promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006397//mRNA processing;GO:0044764;GO:0006289//nucleotide-excision repair;GO:0000377;GO:0006360//transcription from RNA polymerase I promoter;GO:0006383//transcription from RNA polymerase III promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006397//mRNA processing;GO:0044764;GO:0006289//nucleotide-excision repair;GO:0000377;GO:0006360//transcription from RNA polymerase I promoter "gi|148676881|gb|EDL08828.1|/1.351e-60/mCG145114, partial [Mus musculus]" 12261 1177 123.9366667 132.9366667 0.101136012 Up 0.273985483 C1qbp "complement component 1, q subcomponent binding protein" "K15414|1|2e-155|551|mmu:12261|complement component 1 Q subcomponent-binding protein, mitochondrial" GO:0031981//nuclear lumen;GO:0044429;GO:0016020//membrane;GO:0044421 GO:0003712//transcription cofactor activity;GO:0005539//glycosaminoglycan binding;GO:0043022//ribosome binding;GO:0001664//G-protein coupled receptor binding;GO:0003723//RNA binding;GO:0019901//protein kinase binding;GO:0001846//opsonin binding "GO:0010822//positive regulation of mitochondrion organization;GO:0006915//apoptotic process;GO:0002698;GO:0039530//MDA-5 signaling pathway;GO:0010770//positive regulation of cell morphogenesis involved in differentiation;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0039529//RIG-I signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0002407//dendritic cell chemotaxis;GO:0006366//transcription from RNA polymerase II promoter;GO:0007155//cell adhesion;GO:0000398//mRNA splicing, via spliceosome;GO:0002673//regulation of acute inflammatory response;GO:0001818//negative regulation of cytokine production;GO:0042255//ribosome assembly" "gi|148680687|gb|EDL12634.1|/3.55683e-166/complement component 1, q subcomponent binding protein, isoform CRA_a, partial [Mus musculus]" 229663 4056.16 119.7066667 128.7 0.104508553 Up 0.273966678 Csde1 "cold shock domain containing E1, RNA binding" K11970|1|6e-15|86.7|xma:102230073|p53-associated parkin-like cytoplasmic protein GO:0019866//organelle inner membrane;GO:0019866//organelle inner membrane;GO:0019866//organelle inner membrane GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|74192859|dbj|BAE34939.1|/0/unnamed protein product [Mus musculus] 72361 2859 0.973333333 0.683333333 -0.510344459 Down 0.273929068 Ces2g carboxylesterase 2G K03927|1|0.0|1102|mmu:72361|carboxylesterase 2 [EC:3.1.1.1 3.1.1.84 3.1.1.56] GO:0043227//membrane-bounded organelle GO:0052689//carboxylic ester hydrolase activity - gi|268839831|ref|NP_932116.2|/0/carboxylesterase 2-like precursor [Mus musculus] 329628 16109 0.976666667 0.686666667 -0.508256327 Down 0.273929068 Fat4 FAT atypical cadherin 4 K16669|1|0.0|9667|mmu:329628|protocadherin Fat 4 - - - - 170759 3915 10.23666667 11.25333333 0.136606392 Up 0.273882056 Atp13a1 ATPase type 13A1 K14950|1|0.0|2165|mmu:170759|cation-transporting ATPase 13A1 [EC:3.6.3.-] GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0008324//cation transmembrane transporter activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0006811//ion transport gi|283135194|ref|NP_573487.2|/0/manganese-transporting ATPase 13A1 [Mus musculus] 66615 2964 10.38333333 11.40666667 0.135607597 Up 0.273882056 Atg4b "autophagy related 4B, cysteine peptidase" K08342|1|0.0|754|mmu:66615|cysteine protease ATG4 [EC:3.4.22.-] GO:0044424 GO:0005488//binding;GO:0004175//endopeptidase activity GO:0009896;GO:0045184//establishment of protein localization;GO:0019538//protein metabolic process;GO:0007033//vacuole organization;GO:0006914//autophagy gi|27883848|ref|NP_777363.1|/0/cysteine protease ATG4B [Mus musculus] 26370 1186 10.27333333 11.29333333 0.136567013 Up 0.273882056 Cetn2 centrin 2 K10840|1|4e-82|307|rno:84593|centrin-2 GO:0005813//centrosome;GO:0000109//nucleotide-excision repair complex;GO:0031513//nonmotile primary cilium "GO:0032550;GO:0046872//metal ion binding;GO:0042623//ATPase activity, coupled;GO:0032403//protein complex binding;GO:0015631//tubulin binding" GO:0006281//DNA repair;GO:0000910//cytokinesis;GO:0000087//mitotic M phase;GO:0007017//microtubule-based process gi|564297906|ref|XP_001053739.3|/3.56855e-81/PREDICTED: centrin-2 isoform X1 [Rattus norvegicus] 78777 2784 4.946666667 5.606666667 0.180686614 Up 0.273825642 Enthd2 ENTH domain containing 2 "K14996|1|4e-37|159|gfr:102038199|solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 10" GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle - - gi|118130817|ref|NP_898960.2|/0/AP-4 complex accessory subunit tepsin [Mus musculus] 83924 2996 2.006666667 1.616666667 -0.31177874 Down 0.273806837 Gpr137b G protein-coupled receptor 137B - GO:0005764//lysosome;GO:0016021//integral component of membrane - - gi|148612872|ref|NP_114388.2|/0/integral membrane protein GPR137B [Mus musculus] 100470 1958 0.58 0.336666667 -0.784732013 Down 0.273797435 Lao1 L-amino acid oxidase 1 K03334|1|0.0|996|mmu:100470|L-amino-acid oxidase [EC:1.4.3.2] - "GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor" GO:0006520//cellular amino acid metabolic process gi|227500024|ref|NP_598653.3|/0/L-amino acid oxidase 1 precursor [Mus musculus] 66573 4914 0.33 0.566666667 0.780034316 Up 0.273797435 Dzip1 DAZ interacting protein 1 K16470|1|0.0|1356|mmu:66573|zinc finger protein DZIP1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0010927;GO:0048232//male gamete generation;GO:0010927;GO:0048232//male gamete generation gi|57242788|ref|NP_080219.2|/0/zinc finger protein DZIP1 [Mus musculus] 100504486 2815 0.12 0.31 1.36923381 Up 0.273722216 Gdap10 ganglioside-induced differentiation-associated-protein 10 - - - - gi|3378472|emb|CAA76896.1|/1.18336e-58/ganglioside-induced differentiation associated protein 10 [Mus musculus] 12696 1256 32.54 35.14666667 0.111173619 Up 0.273712814 Cirbp cold inducible RNA binding protein K13195|1|1e-49|199|fca:101085782|cold-inducible RNA-binding protein - - - gi|672057891|ref|XP_006241075.2|/1.96484e-52/PREDICTED: cold-inducible RNA-binding protein isoform X2 [Rattus norvegicus] 27261 1546 2.56 3.026666667 0.241585987 Up 0.273665802 Dok3 docking protein 3 K14752|1|2e-53|212|gga:430423|docking protein 1 GO:0016020//membrane;GO:0044424 GO:0008289//lipid binding GO:0007264//small GTPase mediated signal transduction gi|7305003|ref|NP_038767.1|/0/docking protein 3 [Mus musculus] 235028 3431.49 2.626666667 3.093333333 0.235929176 Up 0.273665802 Zfp426 zinc finger protein 426 K09228|1|0.0|1155|mmu:235028|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" "gi|148693158|gb|EDL25105.1|/0/zinc finger protein 426, isoform CRA_d [Mus musculus]" 235339 4051 122.8433333 114.28 -0.104246624 Down 0.273665802 Dlat dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) K00627|1|0.0|1083|mmu:235339|pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12] GO:0043234//protein complex;GO:0005759//mitochondrial matrix GO:0016418//S-acetyltransferase activity GO:0006085//acetyl-CoA biosynthetic process;GO:0019318//hexose metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0044707 "gi|257796245|ref|NP_663589.3|/0/dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial [Mus musculus]" 231769 3319 14.55666667 13.33666667 -0.126281902 Down 0.273637594 Sfswap "splicing factor, suppressor of white-apricot homolog (Drosophila)" "K13168|1|4e-06|57.0|smm:Smp_124100|splicing factor, arginine/serine-rich 16" - - "GO:0000398//mRNA splicing, via spliceosome" "gi|78217391|ref|NP_758480.2|/0/splicing factor, suppressor of white-apricot homolog [Mus musculus]" 621998 1422 0.316666667 0.123333333 -1.360402243 Down 0.27361879 Gm6277 predicted gene 6277 - - - - - 328329 10671 3.31 2.816666667 -0.232842376 Down 0.273571778 Mast4 microtubule associated serine/threonine kinase family member 4 K08789|1|0.0|4463|mmu:328329|microtubule-associated serine/threonine kinase [EC:2.7.11.1] - - - gi|257467645|ref|NP_780380.2|/0/microtubule-associated serine/threonine-protein kinase 4 [Mus musculus] 23999 1594 128.8066667 120.36 -0.097851253 Down 0.273571778 Twf2 twinfilin actin binding protein 2 K08870|1|0.0|666|mmu:23999|twinfilin GO:0043005//neuron projection;GO:0005902//microvillus;GO:0031252//cell leading edge;GO:0043292//contractile fiber GO:0032550;GO:0019901//protein kinase binding;GO:0003779//actin binding;GO:0043168//anion binding GO:0070848//response to growth factor;GO:0030307//positive regulation of cell growth;GO:0032526//response to retinoic acid;GO:0010975//regulation of neuron projection development;GO:0032530;GO:0010591//regulation of lamellipodium assembly;GO:0051693//actin filament capping gi|6755224|ref|NP_036006.1|/0/twinfilin-2 [Mus musculus] 217303 4642 2.836666667 3.326666667 0.229880684 Up 0.273571778 Cd300a CD300A molecule K06719|1|1e-138|497|mmu:217303|CD300A/C/E/H antigen GO:0031224//intrinsic component of membrane GO:0019899//enzyme binding GO:0001820//serotonin secretion;GO:0006897//endocytosis;GO:0033007//negative regulation of mast cell activation involved in immune response gi|25092741|ref|NP_739564.1|/9.98376e-138/CMRF35-like molecule 8 precursor [Mus musculus] 67727 5777 4.85 4.243333333 -0.192786734 Down 0.273534168 Stx17 syntaxin 17 K08491|1|3e-116|423|mmu:67727|syntaxin 17 - - - gi|84579893|ref|NP_080619.2|/3.02278e-115/syntaxin-17 [Mus musculus] 58911 2601 6.313333333 5.603333333 -0.172116606 Down 0.27342134 Sumf1 sulfatase modifying factor 1 K13444|1|0.0|739|mmu:58911|sulfatase modifying factor 1 GO:0044432 GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0003824//catalytic activity GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006664//glycolipid metabolic process gi|74207135|dbj|BAE30762.1|/0/unnamed protein product [Mus musculus] 67013 1866 19.15 20.77333333 0.117388341 Up 0.273402535 Oma1 OMA1 zinc metallopeptidase - GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0005740//mitochondrial envelope GO:0043169//cation binding;GO:0004175//endopeptidase activity GO:0019318//hexose metabolic process;GO:0008053//mitochondrial fusion;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0002021//response to dietary excess;GO:0007007//inner mitochondrial membrane organization;GO:0016485//protein processing;GO:0048871//multicellular organismal homeostasis "gi|21313180|ref|NP_080185.1|/0/metalloendopeptidase OMA1, mitochondrial precursor [Mus musculus]" 66335 2117 19.43 21.05 0.115534332 Up 0.273402535 Atp6v1c1 "ATPase, H+ transporting, lysosomal V1 subunit C1" K02148|1|0.0|736|mmu:66335|V-type H+-transporting ATPase subunit C GO:0031982//vesicle;GO:0033176//proton-transporting V-type ATPase complex;GO:0044444//cytoplasmic part GO:0019829//cation-transporting ATPase activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0005488//binding "GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0015031//protein transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006996//organelle organization;GO:0009154//purine ribonucleotide catabolic process;GO:0044403//symbiosis, encompassing mutualism through parasitism;GO:0006875//cellular metal ion homeostasis" gi|189339262|ref|NP_079770.2|/0/V-type proton ATPase subunit C 1 [Mus musculus] 214897 7183 1.243333333 1.596666667 0.360850025 Up 0.273364925 Csnk1g1 "casein kinase 1, gamma 1" "K08958|1|0.0|898|mmu:214897|casein kinase 1, gamma [EC:2.7.11.1]" - - - "gi|148694162|gb|EDL26109.1|/0/casein kinase 1, gamma 1, partial [Mus musculus]" 18613 3266.26 117.2166667 109.01 -0.10471723 Down 0.273336718 Pecam1 platelet/endothelial cell adhesion molecule 1 K06471|1|0.0|1370|mmu:18613|platelet/endothelial cell adhesion molecule GO:0009986//cell surface;GO:0044425;GO:0044421;GO:0043292//contractile fiber;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0043292//contractile fiber;GO:0044421 GO:0005488//binding;GO:0005488//binding GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0009611//response to wounding;GO:0030041//actin filament polymerization;GO:0045123//cellular extravasation;GO:0001933//negative regulation of protein phosphorylation;GO:0006897//endocytosis;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0001933//negative regulation of protein phosphorylation;GO:0010033//response to organic substance;GO:0022610;GO:0006897//endocytosis;GO:0045123//cellular extravasation;GO:0030041//actin filament polymerization;GO:0009611//response to wounding;GO:0072012//glomerulus vasculature development gi|761631371|ref|NP_001292086.1|/0/platelet endothelial cell adhesion molecule isoform 3 precursor [Mus musculus] 268697 2316 0.403333333 0.656666667 0.703188582 Up 0.273327316 Ccnb1 cyclin B1 K05868|1|0.0|748|mmu:268697|cyclin B GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0000778//condensed nuclear chromosome kinetochore GO:0004672//protein kinase activity;GO:0005102//receptor binding;GO:0019900//kinase binding GO:0008284//positive regulation of cell proliferation;GO:0000070//mitotic sister chromatid segregation;GO:0003006//developmental process involved in reproduction;GO:0043009//chordate embryonic development;GO:0010041//response to iron(III) ion;GO:0048232//male gamete generation;GO:0014070//response to organic cyclic compound;GO:0051726//regulation of cell cycle;GO:0001666//response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0030261//chromosome condensation;GO:0009605//response to external stimulus;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0065003;GO:0070542//response to fatty acid;GO:0007093//mitotic cell cycle checkpoint;GO:0017085//response to insecticide;GO:0031124//mRNA 3'-end processing gi|74200173|dbj|BAE22901.1|/0/unnamed protein product [Mus musculus] 12798 1800 35.04666667 32.49666667 -0.108985492 Down 0.273205085 Cnn2 calponin 2 "K07441|1|1e-96|356|gga:424484|beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141];K06712|2|9e-40|167|myb:102249966|butyrophilin;K20526|3|2e-38|163|bfo:BRAFLDRAFT_61874|transgelin" GO:0030054//cell junction;GO:0032432//actin filament bundle GO:0008092//cytoskeletal protein binding GO:0016477//cell migration;GO:0048534//hematopoietic or lymphoid organ development;GO:0006909//phagocytosis;GO:0009611//response to wounding;GO:0030036//actin cytoskeleton organization;GO:0010467//gene expression;GO:0008283//cell proliferation;GO:0009612//response to mechanical stimulus gi|6680952|ref|NP_031751.1|/1.74635e-163/calponin-2 [Mus musculus] 654409 3091 1.366666667 1.036666667 -0.398709329 Down 0.273111061 4932416H05Rik RIKEN cDNA 4932416H05 gene K08859|1|6e-56|222|rno:311419|serine/threonine kinase 35 [EC:2.7.11.1] - - - gi|148696300|gb|EDL28247.1|/5.48654e-65/serine/threonine kinase 35 [Mus musculus] 20322 2259 112.19 120.0566667 0.09777143 Up 0.273092256 Sord sorbitol dehydrogenase K00008|1|0.0|724|mmu:20322|L-iditol 2-dehydrogenase [EC:1.1.1.14] GO:0005929//cilium;GO:0005740//mitochondrial envelope "GO:0046914//transition metal ion binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0005515//protein binding;GO:0000166//nucleotide binding" GO:0010038//response to metal ion;GO:0048870//cell motility;GO:0009719;GO:0019527;GO:0006060//sorbitol metabolic process;GO:0009991//response to extracellular stimulus;GO:0006000//fructose metabolic process;GO:0006950//response to stress "gi|1009706|gb|AAA79043.1|/0/sorbitol dehydrogenase precursor, partial [Mus musculus domesticus]" 69517 459 0.456666667 0.233333333 -0.968749066 Down 0.273064049 2310001K24Rik RIKEN cDNA 2310001K24 gene - - - - gi|12843636|dbj|BAB26054.1|/2.43201e-41/unnamed protein product [Mus musculus] 21886 2830.92 3.973333333 3.436666667 -0.209339903 Down 0.273045244 Tle2 transducin-like enhancer of split 2 K04497|1|0.0|680|dre:30206|groucho GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - "GO:0030178//negative regulation of Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0030178//negative regulation of Wnt signaling pathway;GO:0006351//transcription, DNA-templated" gi|9789971|ref|NP_062699.1|/0/transducin-like enhancer protein 2 isoform 1 [Mus musculus] 320332 439 0.126666667 0.01 -3.662965013 Down 0.272857197 Hist4h4 "histone cluster 4, H4" K11254|1|3e-42|172|ocu:100343399|histone H4;K11253|4|1e-40|166|cfa:488306|histone H3 - - - gi|655840030|ref|XP_008260749.1|/2.46895e-41/PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC100343399 [Oryctolagus cuniculus] 11450 1233 0.126666667 0.01 -3.662965013 Down 0.272857197 Adipoq "adiponectin, C1Q and collagen domain containing" K07296|1|4e-140|500|mmu:11450|adiponectin - - - - 68369 824 0.01 0.126666667 3.662965013 Up 0.272857197 0610031O16Rik RIKEN cDNA 0610031O16 gene - - - - - 75558 428 0.126666667 0.01 -3.662965013 Down 0.272857197 Spata45 spermatogenesis associated 45 - - - - gi|12839254|dbj|BAB24485.1|/4.9247e-55/unnamed protein product [Mus musculus] 26415 1406 0.01 0.126666667 3.662965013 Up 0.272857197 Mapk13 mitogen-activated protein kinase 13 K04441|1|0.0|704|mmu:26415|p38 MAP kinase [EC:2.7.11.24] - GO:0032550;GO:0004702//receptor signaling protein serine/threonine kinase activity "GO:0006468//protein phosphorylation;GO:0001819//positive regulation of cytokine production;GO:0006351//transcription, DNA-templated;GO:0006950//response to stress" gi|226246627|ref|NP_036080.2|/0/mitogen-activated protein kinase 13 [Mus musculus] 74202 3058.27 114.86 107.3633333 -0.097375098 Down 0.272800782 Fblim1 filamin binding LIM protein 1 K06273|1|2e-56|224|mcf:102124156|zyxin GO:0005856//cytoskeleton;GO:0043227//membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0043227//membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding GO:0022604//regulation of cell morphogenesis;GO:0033622//integrin activation;GO:0007155//cell adhesion;GO:0022604//regulation of cell morphogenesis;GO:0033622//integrin activation;GO:0007155//cell adhesion gi|568931972|ref|XP_006539276.1|/0/PREDICTED: filamin-binding LIM protein 1 isoform X2 [Mus musculus] 67468 2780 12.84666667 14.05 0.12917606 Up 0.272763173 Mmd monocyte to macrophage differentiation-associated K11064|1|1e-133|480|rno:303439|monocyte to macrophage differentiation protein GO:0005770//late endosome;GO:0005764//lysosome;GO:0016021//integral component of membrane - GO:0008219//cell death gi|821012182|ref|XP_012358808.1|/3.08909e-141/PREDICTED: monocyte to macrophage differentiation factor isoform X1 [Nomascus leucogenys] 66333 1322 0.793333333 1.096666667 0.46712601 Up 0.27275377 Aqp11 aquaporin 11 K09870|1|6e-146|519|mmu:66333|aquaporin-11 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0044444//cytoplasmic part GO:0005372//water transmembrane transporter activity GO:0051259//protein oligomerization;GO:0019755;GO:0072080//nephron tubule development;GO:0008643//carbohydrate transport;GO:0007032//endosome organization;GO:0042044//fluid transport "gi|22477736|gb|AAH37088.1|/1.96915e-147/Aqp11 protein, partial [Mus musculus]" 93702 4522 0.78 1.08 0.469485283 Up 0.27275377 Pcdhgb5 "protocadherin gamma subfamily B, 5" K16496|1|0.0|1678|mmu:93702|protocadherin gamma subfamily B GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|18087739|ref|NP_291055.1|/0/protocadherin gamma-B5 precursor [Mus musculus] 230935 2944 34.53 32.02666667 -0.108576684 Down 0.272725563 Dnajc11 DnaJ heat shock protein family (Hsp40) member C11 K09531|1|0.0|1060|mmu:230935|DnaJ homolog subfamily C member 11 - - - - 67923 1116.02 33.43666667 30.93666667 -0.112113272 Down 0.272725563 Tceb1 "transcription elongation factor B (SIII), polypeptide 1" "K03872|1|2e-59|231|xtr:549174|transcription elongation factor B, polypeptide 1" GO:0031981//nuclear lumen;GO:0000153//cytoplasmic ubiquitin ligase complex "GO:0005515//protein binding;GO:0008135//translation factor activity, RNA binding;GO:0019787//ubiquitin-like protein transferase activity" GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006412//translation;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0001666//response to hypoxia;GO:0032446//protein modification by small protein conjugation;GO:0019941//modification-dependent protein catabolic process;GO:0006368//transcription elongation from RNA polymerase II promoter gi|902875571|ref|XP_013027909.1|/7.51445e-55/PREDICTED: transcription elongation factor B polypeptide 1 isoform X1 [Anser cygnoides domesticus] 66206 1428 5.653333333 5.003333333 -0.176212193 Down 0.272697356 1110059E24Rik RIKEN cDNA 1110059E24 gene - - - - gi|13384816|ref|NP_079699.1|/9.12172e-61/uncharacterized protein C9orf85 homolog [Mus musculus] 278795 2077 0.63 0.913333333 0.535789659 Up 0.272687954 Lrrc10b leucine rich repeat containing 10B K16175|1|3e-14|83.2|soc:105202532|protein scribble - - - gi|162287221|ref|NP_001104610.1|/1.78354e-138/leucine-rich repeat-containing protein 10B [Mus musculus] 57138 6042 0.65 0.403333333 -0.688467076 Down 0.272659747 Slc12a5 "solute carrier family 12, member 5" "K14427|1|0.0|2085|mmu:57138|solute carrier family 12 (potassium/chloride transporter), member 4/5/6" GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0032589//neuron projection membrane;GO:0043025//neuronal cell body GO:0015377//cation:chloride symporter activity GO:0007267//cell-cell signaling;GO:0015672//monovalent inorganic cation transport;GO:0040007//growth;GO:0007611//learning or memory;GO:0009266//response to temperature stimulus;GO:0045851//pH reduction;GO:0042221//response to chemical;GO:0015698//inorganic anion transport;GO:0030001//metal ion transport gi|28972652|dbj|BAC65742.1|/0/mKIAA1176 protein [Mus musculus] 214063 3913 10.62666667 9.63 -0.142081425 Down 0.272650344 Dnajc16 DnaJ heat shock protein family (Hsp40) member C16 K09536|1|0.0|1454|mmu:214063|DnaJ homolog subfamily C member 16 - - - - 432731 3990 6.793333333 7.57 0.156173655 Up 0.272622137 Zscan26 zinc finger and SCAN domain containing 26 K09230|1|0.0|720|mmu:432731|SCAN domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated;GO:0044764" gi|161353485|ref|NP_001013808.2|/0/zinc finger and SCAN domain-containing protein 26 [Mus musculus] 18798 3692 7.223333333 6.443333333 -0.164857516 Down 0.272622137 Plcb4 "phospholipase C, beta 4" "K05858|1|0.0|2301|mmu:18798|phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]" GO:0044327//dendritic spine head;GO:0005783//endoplasmic reticulum GO:0004629//phospholipase C activity;GO:0046872//metal ion binding;GO:0060089;GO:0019901//protein kinase binding GO:0006629//lipid metabolic process;GO:0006813//potassium ion transport;GO:0007165//signal transduction "gi|29293803|ref|NP_038857.1|/0/1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 [Mus musculus]" 11409 1881 104.2666667 111.6 0.098059015 Up 0.272622137 Acads "acyl-Coenzyme A dehydrogenase, short chain" K00248|1|0.0|736|mmu:11409|butyryl-CoA dehydrogenase [EC:1.3.8.1] GO:0005740//mitochondrial envelope "GO:0052890//oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor;GO:0000166//nucleotide binding" GO:0019605//butyrate metabolic process;GO:0051260//protein homooligomerization;GO:0006635//fatty acid beta-oxidation;GO:0031960//response to corticosteroid;GO:0006950//response to stress "gi|31982522|ref|NP_031409.2|/0/short-chain specific acyl-CoA dehydrogenase, mitochondrial precursor [Mus musculus]" 620631 2008 0.24 0.463333333 0.949016071 Up 0.272528113 Ttc30a2 tetratricopeptide repeat domain 30A2 K19683|1|0.0|1274|mmu:620631|tetratricopeptide repeat protein 30 GO:0043231//intracellular membrane-bounded organelle - GO:0016043//cellular component organization gi|124487007|ref|NP_001074697.1|/0/tetratricopeptide repeat protein 30A2 [Mus musculus] 71085 5150 0.473333333 0.73 0.62503994 Up 0.272528113 Arhgap19 Rho GTPase activating protein 19 K18470|1|1e-13|82.8|aqu:100637844|Rho GTPase-activating protein 1 GO:0044464;GO:0044464 GO:0008047//enzyme activator activity;GO:0008047//enzyme activator activity GO:0007154//cell communication;GO:0007154//cell communication "gi|148709914|gb|EDL41860.1|/0/Rho GTPase activating protein 19, isoform CRA_a, partial [Mus musculus]" 97064 4767 19.16666667 17.58333333 -0.124390862 Down 0.272518711 Wwtr1 WW domain containing transcription regulator 1 K16820|1|0.0|654|mmu:97064|WW domain-containing transcription regulator protein 1 GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0003712//transcription cofactor activity;GO:0042802//identical protein binding;GO:0003712//transcription cofactor activity;GO:0042802//identical protein binding GO:0007184//SMAD protein import into nucleus;GO:0048858//cell projection morphogenesis;GO:0051301//cell division;GO:0035411//catenin import into nucleus;GO:0001503//ossification;GO:0001933//negative regulation of protein phosphorylation;GO:0001837//epithelial to mesenchymal transition;GO:0045444//fat cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0035556//intracellular signal transduction;GO:0007184//SMAD protein import into nucleus;GO:0048858//cell projection morphogenesis;GO:0051301//cell division;GO:0035411//catenin import into nucleus;GO:0001503//ossification;GO:0001933//negative regulation of protein phosphorylation;GO:0001837//epithelial to mesenchymal transition;GO:0045444//fat cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0035556//intracellular signal transduction gi|270265874|ref|NP_001161753.1|/0/WW domain-containing transcription regulator protein 1 isoform 1 [Mus musculus] 96957 2886 1.796666667 2.193333333 0.287802311 Up 0.272481101 Tmem62 transmembrane protein 62 - GO:0031224//intrinsic component of membrane - - "gi|148696078|gb|EDL28025.1|/0/transmembrane protein 62, isoform CRA_b, partial [Mus musculus]" 72674 3155.15 98.18 105.24 0.100182082 Up 0.272415285 Adipor1 adiponectin receptor 1 K07297|1|0.0|679|mmu:72674|adiponectin receptor GO:0031224//intrinsic component of membrane;GO:0005886//plasma membrane;GO:0031224//intrinsic component of membrane;GO:0005886//plasma membrane GO:0019900//kinase binding;GO:0046983//protein dimerization activity;GO:0019900//kinase binding;GO:0046983//protein dimerization activity GO:0008286//insulin receptor signaling pathway;GO:0006631//fatty acid metabolic process;GO:0016049//cell growth;GO:0007259//JAK-STAT cascade;GO:0019221//cytokine-mediated signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0006631//fatty acid metabolic process;GO:0016049//cell growth;GO:0007259//JAK-STAT cascade;GO:0019221//cytokine-mediated signaling pathway gi|38259186|ref|NP_082596.2|/0/adiponectin receptor protein 1 [Mus musculus] 18519 4260.4 19.97666667 18.41 -0.117826246 Down 0.272293054 Kat2b K(lysine) acetyltransferase 2B K06062|1|0.0|1391|mmu:18519|histone acetyltransferase [EC:2.3.1.48] "GO:0000123//histone acetyltransferase complex;GO:0015629//actin cytoskeleton;GO:0000775//chromosome, centromeric region;GO:0030017//sarcomere;GO:0000123//histone acetyltransferase complex;GO:0015629//actin cytoskeleton;GO:0000775//chromosome, centromeric region;GO:0030017//sarcomere" GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0003712//transcription cofactor activity;GO:0008080//N-acetyltransferase activity;GO:0019900//kinase binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0003712//transcription cofactor activity;GO:0008080//N-acetyltransferase activity;GO:0019900//kinase binding GO:0032868//response to insulin;GO:0006366//transcription from RNA polymerase II promoter;GO:0006474//N-terminal protein amino acid acetylation;GO:0008283//cell proliferation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0016573//histone acetylation;GO:0006471//protein ADP-ribosylation;GO:0032868//response to insulin;GO:0006366//transcription from RNA polymerase II promoter;GO:0006474//N-terminal protein amino acid acetylation;GO:0008283//cell proliferation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0016573//histone acetylation;GO:0006471//protein ADP-ribosylation "gi|148691718|gb|EDL23665.1|/0/p300/CBP-associated factor, isoform CRA_a, partial [Mus musculus]" 72243 695 1.7 1.34 -0.343301746 Down 0.272283651 1700012D01Rik RIKEN cDNA 1700012D01 gene - - - - - 73845 2801 0.023333333 0.163333333 2.807354922 Up 0.272208432 Ankrd42 ankyrin repeat domain 42 K17593|1|0.0|983|cjc:100392468|ankyrin repeat domain-containing protein 42 - - - "gi|826286496|ref|XP_012497232.1|/0/PREDICTED: ankyrin repeat domain-containing protein 42, partial [Propithecus coquereli]" 17096 3393 10.53 9.543333333 -0.141940267 Down 0.272180225 Lyn "LYN proto-oncogene, Src family tyrosine kinase" K05854|1|0.0|1011|ngi:103734185|tyrosine-protein kinase Lyn [EC:2.7.10.2] - - - - 667213 642 0.24 0.46 0.938599455 Up 0.27216142 Gm10416 zinc finger protein pseudogene K09228|1|2e-15|53.9|cge:103159023|KRAB domain-containing zinc finger protein - - - "gi|148688111|gb|EDL20058.1|/1.23303e-19/mCG142615, partial [Mus musculus]" 211949 2232 2.056666667 2.476666667 0.268091721 Up 0.272152018 Spsb4 splA/ryanodine receptor domain and SOCS box containing 4 K10343|1|3e-158|561|rno:300950|SPRY domain-containing SOCS box protein 1/4 GO:0044424 - GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation gi|21553087|ref|NP_660116.1|/2.44428e-157/SPRY domain-containing SOCS box protein 4 [Mus musculus] 73710 1922 2.46 2.043333333 -0.267733742 Down 0.272152018 Tubb2b "tubulin, beta 2B class IIB" K07375|1|0.0|836|gja:107123843|tubulin beta GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0015630//microtubule cytoskeleton GO:0005198//structural molecule activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0006458//'de novo' protein folding;GO:0043623//cellular protein complex assembly;GO:0009154//purine ribonucleotide catabolic process;GO:0016477//cell migration gi|998662027|ref|XP_015507719.1|/0/PREDICTED: tubulin beta-1 chain-like [Parus major] 170644 6455 8.676666667 7.816666667 -0.150587389 Down 0.272133213 Ubn1 ubinuclein 1 K17492|1|0.0|1734|mmu:170644|ubinuclein GO:0043296//apical junction complex;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding GO:0010921//regulation of phosphatase activity;GO:0006325//chromatin organization;GO:0009913//epidermal cell differentiation gi|71534247|ref|NP_080942.1|/0/ubinuclein-1 [Mus musculus] 19698 2218 4.833333333 4.236666667 -0.19008887 Down 0.272114408 Relb avian reticuloendotheliosis viral (v-rel) oncogene related B K09253|1|0.0|977|mmu:19698|transcription factor RelB GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0001773//myeloid dendritic cell activation;GO:0042088//T-helper 1 type immune response;GO:0006351//transcription, DNA-templated;GO:0001773//myeloid dendritic cell activation;GO:0042088//T-helper 1 type immune response;GO:0006351//transcription, DNA-templated" "gi|148691222|gb|EDL23169.1|/0/avian reticuloendotheliosis viral (v-rel) oncogene related B, partial [Mus musculus]" 231713 3105 4.753333333 4.156666667 -0.193512517 Down 0.272114408 Naa25 "N(alpha)-acetyltransferase 25, NatB auxiliary subunit" K17973|1|0.0|1729|mmu:231713|N-terminal acetyltransferase B complex non-catalytic subunit GO:0044424 - - "gi|55742803|ref|NP_766310.2|/0/N-alpha-acetyltransferase 25, NatB auxiliary subunit [Mus musculus]" 100041108 582 0.586666667 0.346666667 -0.7589919 Down 0.272105006 Gm3143 predicted gene 3143 - - - - - 20020 6736 19.18333333 17.62 -0.122639503 Down 0.272076799 Polr2a polymerase (RNA) II (DNA directed) polypeptide A K03006|1|0.0|3067|oas:100144762|DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] "GO:0016591//DNA-directed RNA polymerase II, holoenzyme" GO:0016301//kinase activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006397//mRNA processing;GO:0044764;GO:0006289//nucleotide-excision repair;GO:0000377;GO:0006464//cellular protein modification process gi|2145091|gb|AAB58418.1|/0/RNA polymerase II largest subunit [Mus musculus] 15388 2142 89.69333333 96.31666667 0.102784707 Up 0.272029787 Hnrnpl heterogeneous nuclear ribonucleoprotein L K13159|1|0.0|940|mmu:15388|heterogeneous nuclear ribonucleoprotein L GO:0032991//macromolecular complex;GO:0031981//nuclear lumen GO:0036094//small molecule binding;GO:0000975//regulatory region DNA binding GO:0000377 gi|197245939|gb|AAI69048.1|/0/Hnrnpl protein [Rattus norvegicus] 54525 6646.7 13.69 12.51 -0.130040657 Down 0.272020384 Syt7 synaptotagmin VII K19907|1|0.0|1014|ecb:100062526|synaptotagmin-7 GO:0030141//secretory granule;GO:0000323//lytic vacuole;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane;GO:0031224//intrinsic component of membrane;GO:0030141//secretory granule;GO:0000323//lytic vacuole;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic component of membrane;GO:0030141//secretory granule;GO:0000323//lytic vacuole;GO:0008021//synaptic vesicle GO:0046872//metal ion binding;GO:0000149//SNARE binding;GO:0005543//phospholipid binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0000149//SNARE binding;GO:0005543//phospholipid binding GO:0007009//plasma membrane organization;GO:0017156//calcium ion regulated exocytosis;GO:0009593//detection of chemical stimulus;GO:0030073//insulin secretion;GO:0017156//calcium ion regulated exocytosis;GO:0030073//insulin secretion;GO:0007009//plasma membrane organization;GO:0017156//calcium ion regulated exocytosis;GO:0009593//detection of chemical stimulus;GO:0030073//insulin secretion gi|41281824|ref|NP_775090.1|/0/synaptotagmin-7 beta isoform [Mus musculus] 68736 1399 1.42 1.086666667 -0.385981466 Down 0.271898153 Tyw5 tRNA-yW synthesizing protein 5 K18066|1|5e-173|486|mmu:68736|tRNA wybutosine-synthesizing protein 5 [EC:1.14.11.42] - - - gi|166235142|ref|NP_001032831.2|/0/tRNA wybutosine-synthesizing protein 5 isoform 1 [Mus musculus] 231128 5556 7.47 6.7 -0.156947147 Down 0.271879349 Fam193a "family with sequence similarity 193, member A" - - - - gi|341572571|ref|NP_001230052.1|/0/protein FAM193A [Mus musculus] 94044 6933 17.74333333 19.29666667 0.12107459 Up 0.271841739 Bcl2l13 BCL2-like 13 (apoptosis facilitator) K15485|1|0.0|719|mmu:94044|Bcl-2-like protein 13 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0006915//apoptotic process gi|23943828|ref|NP_705736.1|/0/bcl-2-like protein 13 [Mus musculus] 80721 2974 0.13 0.316666667 1.284453389 Up 0.271775922 Slc19a3 "solute carrier family 19, member 3" "K14610|1|0.0|983|mmu:80721|solute carrier family 19 (thiamine transporter), member 2/3" GO:0016021//integral component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0015234//thiamine transmembrane transporter activity GO:0006835//dicarboxylic acid transport;GO:0051180//vitamin transport gi|206597448|ref|NP_085033.2|/0/thiamine transporter 2 [Mus musculus] 11652 3037.46 92.14333333 98.51333333 0.096439211 Up 0.271672496 Akt2 thymoma viral proto-oncogene 2 K04456|1|0.0|986|mmu:11652|RAC serine/threonine-protein kinase [EC:2.7.11.1] - - - - 59287 2864 28.99666667 31.38333333 0.11411153 Up 0.271644289 Ncstn nicastrin K06171|1|0.0|1380|mmu:59287|nicastrin GO:0005764//lysosome;GO:0016021//integral component of membrane;GO:0048770 "GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0005488//binding" GO:0006518//peptide metabolic process;GO:0051604//protein maturation;GO:0044093;GO:0007166//cell surface receptor signaling pathway;GO:0042110//T cell activation;GO:0008283//cell proliferation;GO:0033619//membrane protein proteolysis gi|37359868|dbj|BAC97912.1|/0/mKIAA0253 protein [Mus musculus] 432467 2170 12.92333333 14.09666667 0.125375825 Up 0.271559668 Hnrnph3 heterogeneous nuclear ribonucleoprotein H3 K12898|1|4e-56|222|rno:100910795|heterogeneous nuclear ribonucleoprotein F/H - - - gi|664771896|ref|XP_008505149.1|/4.57224e-60/PREDICTED: heterogeneous nuclear ribonucleoprotein H3 isoform X2 [Equus przewalskii] 28114 4280 13.44333333 12.27 -0.131755656 Down 0.271559668 Nsun2 NOL1/NOP2/Sun domain family member 2 K15335|1|0.0|1535|mmu:28114|tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.203] GO:0015630//microtubule cytoskeleton;GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0016427//tRNA (cytosine) methyltransferase activity GO:0001510//RNA methylation;GO:0000087//mitotic M phase;GO:0006399//tRNA metabolic process "gi|148705068|gb|EDL37015.1|/0/NOL1/NOP2/Sun domain family 2, isoform CRA_a [Mus musculus]" 17165 2229 31.12 28.73666667 -0.114949335 Down 0.271540863 Mapkapk5 MAP kinase-activated protein kinase 5 K04442|1|0.0|956|mmu:17165|mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004672//protein kinase activity;GO:0019901//protein kinase binding GO:0006412//translation;GO:0006468//protein phosphorylation;GO:0009968//negative regulation of signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0090398//cellular senescence gi|6754636|ref|NP_034895.1|/0/MAP kinase-activated protein kinase 5 [Mus musculus] 545681 4446 9.883333333 10.86666667 0.13683986 Up 0.271540863 Gm12992 predicted gene 12992 - - - - - 17395 3189 0.136666667 0.326666667 1.257157839 Up 0.271493851 Mmp9 matrix metallopeptidase 9 K01403|1|0.0|1387|mmu:17395|matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35] GO:0032991//macromolecular complex;GO:0044421;GO:0031012//extracellular matrix GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0001525//angiogenesis;GO:0032496//response to lipopolysaccharide;GO:0040007//growth;GO:0006461//protein complex assembly;GO:0048167//regulation of synaptic plasticity;GO:0010041//response to iron(III) ion;GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0055098//response to low-density lipoprotein particle;GO:0034612//response to tumor necrosis factor;GO:0019048//modulation by virus of host morphology or physiology;GO:0033273//response to vitamin;GO:0009628//response to abiotic stimulus;GO:0097305//response to alcohol;GO:0031668//cellular response to extracellular stimulus;GO:0006950//response to stress;GO:0070555//response to interleukin-1;GO:0043062//extracellular structure organization;GO:0002684//positive regulation of immune system process;GO:0032963//collagen metabolic process;GO:0030335//positive regulation of cell migration;GO:0019538//protein metabolic process gi|12835973|dbj|BAB23442.1|/0/unnamed protein product [Mus musculus] 68498 4209 0.32 0.133333333 -1.263034406 Down 0.271493851 Tspan11 tetraspanin 11 K17352|1|1e-145|520|mmu:68498|tetraspanin-11 GO:0031224//intrinsic component of membrane - - gi|22507385|ref|NP_081019.1|/1.29301e-144/tetraspanin-11 [Mus musculus] 58800 7145 2.556666667 3.02 0.240284473 Up 0.271484448 Trpm7 "transient receptor potential cation channel, subfamily M, member 7" K04982|1|0.0|3664|mmu:58800|transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1] GO:0044297//cell body;GO:0031252//cell leading edge;GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle;GO:0033267;GO:0044297//cell body;GO:0031252//cell leading edge;GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle;GO:0033267 GO:0032550;GO:0004672//protein kinase activity;GO:0008092//cytoskeletal protein binding;GO:0005261//cation channel activity;GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity;GO:0008092//cytoskeletal protein binding;GO:0005261//cation channel activity;GO:0043169//cation binding GO:0007160//cell-matrix adhesion;GO:0007611//learning or memory;GO:0006816//calcium ion transport;GO:0006915//apoptotic process;GO:0030036//actin cytoskeleton organization;GO:0006468//protein phosphorylation;GO:0009628//response to abiotic stimulus;GO:0006875//cellular metal ion homeostasis;GO:0007160//cell-matrix adhesion;GO:0007611//learning or memory;GO:0006816//calcium ion transport;GO:0006915//apoptotic process;GO:0030036//actin cytoskeleton organization;GO:0006468//protein phosphorylation;GO:0009628//response to abiotic stimulus;GO:0006875//cellular metal ion homeostasis gi|256773285|ref|NP_067425.2|/0/transient receptor potential cation channel subfamily M member 7 isoform 1 [Mus musculus] 18173 2304 2.493333333 2.953333333 0.244268429 Up 0.271484448 Slc11a1 "solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1" K12347|1|0.0|1037|mmu:18173|natural resistance-associated macrophage protein GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0019867//outer membrane;GO:0030666//endocytic vesicle membrane;GO:0030667//secretory granule membrane;GO:0005768//endosome GO:0022890//inorganic cation transmembrane transporter activity;GO:0042802//identical protein binding;GO:0046873//metal ion transmembrane transporter activity GO:0006828//manganese ion transport;GO:0015691//cadmium ion transport;GO:0044710;GO:0048871//multicellular organismal homeostasis;GO:0002286//T cell activation involved in immune response;GO:0001562//response to protozoan;GO:0043092;GO:0042742//defense response to bacterium;GO:0002274;GO:0001819//positive regulation of cytokine production;GO:0051452//intracellular pH reduction;GO:0015698//inorganic anion transport;GO:0043488//regulation of mRNA stability;GO:0002367//cytokine production involved in immune response;GO:0002237//response to molecule of bacterial origin;GO:0006366//transcription from RNA polymerase II promoter;GO:0002468//dendritic cell antigen processing and presentation;GO:0002824;GO:0034097//response to cytokine;GO:0006875//cellular metal ion homeostasis;GO:0045860//positive regulation of protein kinase activity;GO:0072503;GO:0009611//response to wounding;GO:0006909//phagocytosis gi|190877473|ref|NP_038640.2|/0/natural resistance-associated macrophage protein 1 [Mus musculus] 76763 3683.57 2.56 3.02 0.238404739 Up 0.271484448 Mospd2 motile sperm domain containing 2 K16663|1|1e-31|141|isc:IscW_ISCW012683|CMRF35-like molecule 9;K06096|2|4e-10|70.5|pxy:105381600|vesicle-associated membrane protein-associated protein A;K10707|3|4e-09|67.0|mcf:102140094|vesicle-associated membrane protein-associated protein B - - - gi|594542462|ref|NP_001277452.1|/0/motile sperm domain-containing protein 2 isoform 2 [Mus musculus] 78372 838 5.606666667 6.296666667 0.167444996 Up 0.271475046 Snrnp25 small nuclear ribonucleoprotein 25 (U11/U12) K13153|1|2e-73|278|hgl:101710350|U11/U12 small nuclear ribonucleoprotein 25 kDa protein - - - gi|351711231|gb|EHB14150.1|/1.29776e-72/U11/U12 small nuclear ribonucleoprotein 25 kDa protein [Heterocephalus glaber] 72475 3135.1 17.80666667 19.34333333 0.119418953 Up 0.271428034 Ssbp3 single-stranded DNA binding protein 3 - - - - - 16000 7066.73 1.186666667 0.88 -0.431339312 Down 0.271390425 Igf1 insulin-like growth factor 1 K05459|1|5e-78|296|tup:102490248|insulin-like growth factor 1 - - - - 69513 1792 1.193333333 0.883333333 -0.433967228 Down 0.271390425 1700030C10Rik RIKEN cDNA 1700030C10 gene "K12488|1|2e-07|60.5|chx:102188413|Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein" - - - - 240334 2017 1.01 0.72 -0.488286481 Down 0.271352815 Pcyox1l prenylcysteine oxidase 1 like K05906|1|0.0|811|ecb:100060629|prenylcysteine oxidase / farnesylcysteine lyase [EC:1.8.3.5 1.8.3.6] - "GO:0016670//oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor" GO:0000098//sulfur amino acid catabolic process gi|27370248|ref|NP_766420.1|/0/prenylcysteine oxidase-like precursor [Mus musculus] 665563 2256 1.516666667 1.89 0.31748219 Up 0.271352815 Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like "K13403|1|7e-176|620|mmu:665563|methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]" - - - gi|124301198|ref|NP_081064.1|/5.85911e-175/probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Mus musculus] 100504007 1250 0.993333333 0.706666667 -0.491248066 Down 0.271352815 Gm15787 predicted gene 15787 K10644|1|3e-15|85.5|shr:100931552|E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27] GO:0016604//nuclear body;GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0019787//ubiquitin-like protein transferase activity GO:0007049//cell cycle;GO:0019941//modification-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0007049//cell cycle;GO:0019941//modification-dependent protein catabolic process;GO:0016567//protein ubiquitination "gi|148688089|gb|EDL20036.1|/7.87224e-40/mCG145971, partial [Mus musculus]" 107528 3584 1.47 1.836666667 0.321273663 Up 0.271352815 Magee1 "melanoma antigen, family E, 1" K12464|1|2e-39|167|pale:102884928|melanoma-associated antigen D1 GO:0043005//neuron projection;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0097060//synaptic membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|111378377|ref|NP_444431.3|/0/melanoma-associated antigen E1 [Mus musculus] 16184 4428 1.013333333 0.723333333 -0.486376281 Down 0.271352815 Il2ra "interleukin 2 receptor, alpha chain" K05068|1|4e-142|509|mmu:16184|interleukin 2 receptor alpha GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0019838//growth factor binding;GO:0004896//cytokine receptor activity GO:0030217//T cell differentiation;GO:0032945//negative regulation of mononuclear cell proliferation;GO:0042102//positive regulation of T cell proliferation;GO:0006915//apoptotic process;GO:0019221//cytokine-mediated signaling pathway;GO:0001777//T cell homeostatic proliferation;GO:0002698;GO:0006954//inflammatory response gi|254540187|ref|NP_032393.3|/3.14422e-141/interleukin-2 receptor subunit alpha precursor [Mus musculus] 20467 1519.69 29.25333333 31.60333333 0.111475708 Up 0.271324608 Sin3b "transcriptional regulator, SIN3B (yeast)" K11644|1|0.0|1569|xtr:779742|paired amphipathic helix protein Sin3a GO:0043231//intracellular membrane-bounded organelle;GO:0000803//sex chromosome GO:0005488//binding;GO:0003712//transcription cofactor activity "GO:0051726//regulation of cell cycle;GO:0007507//heart development;GO:0014706//striated muscle tissue development;GO:0006351//transcription, DNA-templated" gi|164420772|ref|NP_001106719.1|/2.86204e-153/paired amphipathic helix protein Sin3b isoform 2 [Mus musculus] 209047 1024 4.723333333 5.366666667 0.18422093 Up 0.271268194 Gipc3 "GIPC PDZ domain containing family, member 3" K20056|1|4e-149|529|mmu:209047|PDZ domain-containing protein GIPC - - - gi|22507363|ref|NP_683753.1|/3.52397e-148/PDZ domain-containing protein GIPC3 [Mus musculus] 20868 5082 5.393333333 4.75 -0.183249688 Down 0.271268194 Stk10 serine/threonine kinase 10 K08837|1|0.0|1758|mmu:20868|serine/threonine kinase 10 [EC:2.7.11.1] GO:0016020//membrane GO:0032550;GO:0042802//identical protein binding;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0006468//protein phosphorylation;GO:0070486//leukocyte aggregation;GO:0002685//regulation of leukocyte migration gi|60360472|dbj|BAD90480.1|/0/mKIAA4026 protein [Mus musculus] 26457 2795 81.85333333 87.94 0.103478363 Up 0.271268194 Slc27a1 "solute carrier family 27 (fatty acid transporter), member 1" "K08745|1|0.0|1224|mmu:26457|solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]" GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0044459 GO:0015645//fatty acid ligase activity;GO:0005319//lipid transporter activity;GO:0042802//identical protein binding GO:0006655//phosphatidylglycerol biosynthetic process;GO:0006658//phosphatidylserine metabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0046165;GO:0043434//response to peptide hormone;GO:0006631//fatty acid metabolic process;GO:0046337//phosphatidylethanolamine metabolic process;GO:0045860//positive regulation of protein kinase activity;GO:0006950//response to stress;GO:0031649//heat generation;GO:0015908//fatty acid transport;GO:0046473//phosphatidic acid metabolic process gi|568955457|ref|XP_006509733.1|/0/PREDICTED: long-chain fatty acid transport protein 1 isoform X2 [Mus musculus] 84652 5669 3.78 4.343333333 0.200416444 Up 0.271202377 Fam126a "family with sequence similarity 126, member A" K00605|1|2e-15|88.6|tsp:Tsp_07633|aminomethyltransferase [EC:2.1.2.10] GO:0044424;GO:0044424 - - gi|882939072|ref|NP_001297400.1|/0/hyccin isoform 2 [Mus musculus] 100039246 1020 30.73666667 28.4 -0.114069786 Down 0.271202377 Plac9b placenta specific 9b - - - - gi|564387936|ref|XP_006252692.1|/3.49046e-31/PREDICTED: placenta-specific protein 9 isoform X1 [Rattus norvegicus] 70997 2264 4.233333333 3.676666667 -0.203395706 Down 0.271202377 Spef1 sperm flagellar 1 K06540|1|9e-08|61.6|lve:103070000|disintegrin and metalloproteinase domain-containing protein 8 [EC:3.4.24.-] GO:0005929//cilium;GO:0043232 - - gi|110625792|ref|NP_081917.1|/2.68643e-119/sperm flagellar protein 1 [Mus musculus] 226562 10444 4.336666667 3.776666667 -0.199473101 Down 0.271202377 Prrc2c proline-rich coiled-coil 2C "K13219|1|5e-21|108|acs:100568202|splicing factor, proline- and glutamine-rich;K13171|2|1e-06|60.5|lcm:102346247|serine/arginine repetitive matrix protein 1;K12875|3|4e-06|58.5|ola:101170959|apoptotic chromatin condensation inducer in the nucleus" - - - gi|755495599|ref|XP_011237089.1|/0/PREDICTED: protein PRRC2C isoform X11 [Mus musculus] 66177 722.85 84.59666667 90.59666667 0.098857152 Up 0.271127158 Ubl5 ubiquitin-like 5 K13113|1|2e-36|156|mdo:100012958|ubiquitin-like protein 5 GO:0044424 - - gi|894216101|ref|NP_001297675.1|/1.61844e-60/ubiquitin-like protein 5 isoform 1 [Mus musculus] 75677 994 0.356666667 0.596666667 0.742348791 Up 0.271127158 Cldn22 claudin 22 K06087|1|9e-80|299|mmu:75677|claudin GO:0016020//membrane - GO:0034329//cell junction assembly;GO:0045216//cell-cell junction organization gi|162417943|ref|NP_083659.1|/7.31813e-79/claudin-22 [Mus musculus] 22051 1760 12.26 13.42 0.130425693 Up 0.271070744 Trip6 thyroid hormone receptor interactor 6 K12792|1|0.0|810|mmu:22051|thyroid receptor-interacting protein 6 GO:0043231//intracellular membrane-bounded organelle;GO:0005924//cell-substrate adherens junction;GO:0043232;GO:0005887//integral component of plasma membrane GO:0046914//transition metal ion binding;GO:0005126//cytokine receptor binding;GO:0019899//enzyme binding "GO:0006351//transcription, DNA-templated;GO:0022610;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0016477//cell migration" gi|6755879|ref|NP_035769.1|/0/thyroid receptor-interacting protein 6 [Mus musculus] 12764 1760 17.51 19.02666667 0.11984375 Up 0.271051939 Cmas cytidine monophospho-N-acetylneuraminic acid synthetase K00983|1|0.0|810|mmu:12764|N-acylneuraminate cytidylyltransferase [EC:2.7.7.43] GO:0043231//intracellular membrane-bounded organelle GO:0070567 GO:0008610//lipid biosynthetic process;GO:0006040//amino sugar metabolic process gi|247269309|ref|NP_034038.2|/0/N-acylneuraminate cytidylyltransferase [Mus musculus] 105638 2267.83 16.83333333 18.35333333 0.124721222 Up 0.271051939 Dph3 diphthamine biosynthesis 3 K15455|1|6e-43|179|mmu:105638|diphthamide biosynthesis protein 3 GO:0043231//intracellular membrane-bounded organelle;GO:0044424;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen GO:0043169//cation binding;GO:0043169//cation binding;GO:0043169//cation binding;GO:0043169//cation binding GO:0017182;GO:0009306//protein secretion;GO:0044093;GO:0017182;GO:0065007//biological regulation;GO:0017182;GO:0009306//protein secretion;GO:0044093;GO:0017182;GO:0009306//protein secretion;GO:0044093;GO:0017182;GO:0009306//protein secretion;GO:0044093 "gi|148692877|gb|EDL24824.1|/2.58701e-56/zinc finger, CSL domain containing 2, isoform CRA_a, partial [Mus musculus]" 66290 1109 84.54 90.47 0.097805359 Up 0.271051939 Atp6v1g1 "ATPase, H+ transporting, lysosomal V1 subunit G1" K02152|1|2e-43|178|mmu:66290|V-type H+-transporting ATPase subunit G GO:0005774//vacuolar membrane;GO:0005764//lysosome;GO:0030136//clathrin-coated vesicle GO:0019829//cation-transporting ATPase activity;GO:0019899//enzyme binding GO:0006818//hydrogen transport;GO:0009154//purine ribonucleotide catabolic process;GO:0006811//ion transport gi|15617197|ref|NP_077135.1|/1.72826e-42/V-type proton ATPase subunit G 1 [Mus musculus] 320770 5410 1.583333333 1.96 0.307888642 Up 0.27093911 A630072M18Rik RIKEN cDNA A630072M18 gene "K03847|1|2e-06|42.7|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - - 15165 7911 0.223333333 0.056666667 -1.978626349 Down 0.270929708 Hcn1 "hyperpolarization-activated, cyclic nucleotide-gated K+ 1" K04954|1|0.0|1515|mmu:15165|hyperpolarization activated cyclic nucleotide-gated potassium channel 1 GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection GO:0030551//cyclic nucleotide binding;GO:0005267//potassium channel activity GO:0006814//sodium ion transport;GO:0007267//cell-cell signaling;GO:0008105//asymmetric protein localization;GO:0042462//eye photoreceptor cell development;GO:0034220//ion transmembrane transport "gi|148686413|gb|EDL18360.1|/0/hyperpolarization-activated, cyclic nucleotide-gated K+ 1, partial [Mus musculus]" 19230 2973 7.196666667 6.433333333 -0.161762396 Down 0.270873293 Twf1 twinfilin actin binding protein 1 K08870|1|0.0|705|mmu:19230|twinfilin GO:0001726//ruffle;GO:0005856//cytoskeleton;GO:0030054//cell junction;GO:0043292//contractile fiber GO:0032550;GO:0004672//protein kinase activity;GO:0003779//actin binding;GO:0043168//anion binding GO:0001932//regulation of protein phosphorylation;GO:0051693//actin filament capping gi|62990169|ref|NP_032997.3|/0/twinfilin-1 [Mus musculus] 217351 8740 7.113333333 6.356666667 -0.162255333 Down 0.270873293 Tnrc6c trinucleotide repeat containing 6C K18412|1|0.0|3074|mmu:217351|trinucleotide repeat-containing gene 6 protein - - - gi|74184652|dbj|BAE27937.1|/0/unnamed protein product [Mus musculus] 19179 1502 84.02 78.21333333 -0.103318215 Down 0.270845086 Psmc1 "protease (prosome, macropain) 26S subunit, ATPase 1" K03062|1|0.0|783|xtr:733980|26S proteasome regulatory subunit T2 GO:0031981//nuclear lumen;GO:0000502//proteasome complex;GO:0044444//cytoplasmic part GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008134//transcription factor binding "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0006915//apoptotic process;GO:0044764;GO:0051320;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0009154//purine ribonucleotide catabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|676260928|gb|KFO18267.1|/0/26S protease regulatory subunit 4 [Fukomys damarensis] 224630 1100 17.59 19.10333333 0.119068913 Up 0.270807477 Bnip1 BCL2/adenovirus E1B interacting protein 1 K08497|1|7e-113|409|mmu:224630|protein transport protein SEC20 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0031090//organelle membrane;GO:0012505//endomembrane system - GO:0012502//induction of programmed cell death;GO:0006810//transport;GO:0044248;GO:0045184//establishment of protein localization;GO:0048284//organelle fusion "gi|148690568|gb|EDL22515.1|/1.41382e-113/BCL2/adenovirus E1B interacting protein 1, NIP1, isoform CRA_c, partial [Mus musculus]" 12283 3800 31.12333333 28.81 -0.111426922 Down 0.270788672 Cab39 calcium binding protein 39 K08272|1|0.0|673|mmu:12283|calcium binding protein 39 GO:0044424 GO:0004672//protein kinase activity;GO:0019899//enzyme binding;GO:0019887//protein kinase regulator activity GO:0001934//positive regulation of protein phosphorylation "gi|148708308|gb|EDL40255.1|/0/calcium binding protein 39, isoform CRA_b, partial [Mus musculus]" 12282 4432 12.24666667 13.39666667 0.129484951 Up 0.270722855 Hyou1 hypoxia up-regulated 1 K09486|1|0.0|1654|mmu:12282|hypoxia up-regulated 1 GO:0044432 GO:0032550 GO:0006950//response to stress gi|157951706|ref|NP_067370.3|/0/hypoxia up-regulated protein 1 precursor [Mus musculus] 66421 975 11.82666667 12.97333333 0.1335057 Up 0.270722855 2410004B18Rik RIKEN cDNA 2410004B18 gene - - - - gi|12859593|dbj|BAB31704.1|/1.29821e-80/unnamed protein product [Mus musculus] 15387 2825.37 81.49333333 87.20333333 0.09770124 Up 0.270685246 Hnrnpk heterogeneous nuclear ribonucleoprotein K K12886|1|3e-163|578|mdo:100021558|heterogeneous nuclear ribonucleoprotein K GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043566//structure-specific DNA binding" GO:0010984;GO:0006898//receptor-mediated endocytosis;GO:0006915//apoptotic process;GO:0007154//cell communication;GO:0000377;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010870//positive regulation of receptor biosynthetic process;GO:0010984;GO:0006898//receptor-mediated endocytosis;GO:0006915//apoptotic process;GO:0007154//cell communication;GO:0000377;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010870//positive regulation of receptor biosynthetic process;GO:0010984;GO:0006898//receptor-mediated endocytosis;GO:0006915//apoptotic process;GO:0007154//cell communication;GO:0000377;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010870//positive regulation of receptor biosynthetic process;GO:0010984;GO:0006898//receptor-mediated endocytosis;GO:0006915//apoptotic process;GO:0007154//cell communication;GO:0000377;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010870//positive regulation of receptor biosynthetic process;GO:0010984;GO:0006898//receptor-mediated endocytosis;GO:0006915//apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010870//positive regulation of receptor biosynthetic process;GO:0010984;GO:0006898//receptor-mediated endocytosis;GO:0006915//apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010870//positive regulation of receptor biosynthetic process gi|74225344|dbj|BAE31602.1|/3.26692e-170/unnamed protein product [Mus musculus] 56354 2312 30.16 32.45666667 0.105878413 Up 0.270666441 Dnajc7 DnaJ heat shock protein family (Hsp40) member C7 K09527|1|0.0|1038|ngi:103735881|DnaJ homolog subfamily C member 7 - - - - 72293 3222 0.67 0.423333333 -0.662367004 Down 0.270647636 Nkd2 naked cuticle 2 homolog (Drosophila) K03213|1|0.0|833|mmu:72293|naked cuticle GO:0031982//vesicle;GO:0044424;GO:0044459 GO:0044389//ubiquitin-like protein ligase binding;GO:0043169//cation binding GO:0051130//positive regulation of cellular component organization;GO:0006906//vesicle fusion;GO:0006612//protein targeting to membrane;GO:0030178//negative regulation of Wnt signaling pathway;GO:0016485//protein processing;GO:0031331 gi|254588129|ref|NP_082462.3|/0/protein naked cuticle homolog 2 [Mus musculus] 76509 1846 0.3 0.526666667 0.811927652 Up 0.27054421 Plet1 placenta expressed transcript 1 K20358|1|5e-07|58.9|dya:Dyak_GE13647|golgin subfamily A member 2 GO:0044425;GO:0009986//cell surface - - gi|124286797|ref|NP_083915.2|/6.78218e-78/placenta-expressed transcript 1 protein precursor [Mus musculus] 72310 813 0.25 0.47 0.910732662 Up 0.270534808 Nkg7 natural killer cell group 7 sequence - GO:0031224//intrinsic component of membrane - - gi|31980746|ref|NP_077215.2|/6.47246e-90/protein NKG7 [Mus musculus] 66144 635 76.65333333 82.25333333 0.101725616 Up 0.270525405 Atp6v1f "ATPase, H+ transporting, lysosomal V1 subunit F" K02151|1|3e-63|243|pps:100991812|V-type H+-transporting ATPase subunit F GO:0005774//vacuolar membrane;GO:0033176//proton-transporting V-type ATPase complex GO:0019829//cation-transporting ATPase activity "GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient" gi|931574699|ref|XP_003813552.3|/1.93172e-62/PREDICTED: V-type proton ATPase subunit F [Pan paniscus] 72113 2326.56 18.19333333 16.69 -0.124425939 Down 0.270525405 Adck1 aarF domain containing kinase 1 K08869|1|0.0|999|mmu:72113|aarF domain-containing kinase GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|21312430|ref|NP_082381.1|/0/uncharacterized aarF domain-containing protein kinase 1 precursor [Mus musculus] 100415787 2953 0.573333333 0.846666667 0.562419932 Up 0.270487796 Tomm6os "translocase of outer mitochondrial membrane 6, opposite strand" K04511|1|2e-22|110|cmy:102929624|prickle - - - gi|724856242|ref|XP_010367943.1|/1.25098e-42/PREDICTED: prickle-like protein 4 isoform X1 [Rhinopithecus roxellana] 70603 1643 0.923333333 0.643333333 -0.521285129 Down 0.270487796 Mutyh mutY DNA glycosylase K03575|1|0.0|804|mmu:70603|A/G-specific adenine glycosylase [EC:3.2.2.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0043169//cation binding;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0051536//iron-sulfur cluster binding;GO:0032404;GO:0004518//nuclease activity;GO:0043169//cation binding;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0051536//iron-sulfur cluster binding;GO:0032404;GO:0004518//nuclease activity;GO:0043169//cation binding;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0051536//iron-sulfur cluster binding;GO:0032404;GO:0004518//nuclease activity" GO:0006281//DNA repair;GO:0006281//DNA repair;GO:0006281//DNA repair gi|227330621|ref|NP_573513.2|/0/adenine DNA glycosylase isoform a [Mus musculus] 75905 3505 1.306666667 0.983333333 -0.4101387 Down 0.270478393 4930578C19Rik RIKEN cDNA 4930578C19 gene - - - - - 71147 3752 5.51 6.186666667 0.167109986 Up 0.270431381 Oxsm "3-oxoacyl-ACP synthase, mitochondrial" K09458|1|0.0|875|mmu:71147|3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] GO:0043231//intracellular membrane-bounded organelle GO:0004312//fatty acid synthase activity GO:0006633//fatty acid biosynthetic process;GO:0006732 "gi|148688693|gb|EDL20640.1|/0/3-oxoacyl-ACP synthase, mitochondrial, isoform CRA_b, partial [Mus musculus]" 15500 2623 5.423333333 6.103333333 0.17041754 Up 0.270431381 Hsf2 heat shock factor 2 K09415|1|0.0|954|mmu:15500|heat shock transcription factor 2 GO:0031981//nuclear lumen GO:0003712//transcription cofactor activity;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding GO:0050896//response to stimulus;GO:0048232//male gamete generation;GO:0006366//transcription from RNA polymerase II promoter gi|226530977|ref|NP_032323.3|/0/heat shock factor protein 2 [Mus musculus] 68618 1057 9.17 10.13 0.143640535 Up 0.270356162 1110012L19Rik RIKEN cDNA 1110012L19 gene - - GO:0005488//binding - gi|21312070|ref|NP_081063.1|/5.09395e-73/uncharacterized protein CXorf40 homolog [Mus musculus] 54216 7422.97 10.64333333 9.68 -0.1368711 Down 0.270356162 Pcdh7 protocadherin 7 K16498|1|0.0|1860|ptr:461157|protocadherin delta 1 GO:0016021//integral component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|890808805|ref|NP_001297535.1|/0/protocadherin-7 isoform 3 precursor [Mus musculus] 14247 3184 12.83333333 11.69 -0.134621015 Down 0.270233931 Fli1 Friend leukemia integration 1 K09436|1|0.0|918|mmu:14247|friend leukemia integration 1 transcription factor GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding "GO:0050878//regulation of body fluid levels;GO:0030219//megakaryocyte differentiation;GO:0003013//circulatory system process;GO:0006351//transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis" "gi|281351833|gb|EFB27417.1|/0/hypothetical protein PANDA_000485, partial [Ailuropoda melanoleuca]" 16553 6866 18.73 17.23666667 -0.119870095 Down 0.270196322 Kif13a kinesin family member 13A K17914|1|0.0|3245|mmu:16553|kinesin family member 13 GO:0005815//microtubule organizing center;GO:0031090//organelle membrane;GO:0005802//trans-Golgi network GO:0032550;GO:0003774//motor activity GO:0016192//vesicle-mediated transport;GO:0007041//lysosomal transport;GO:0047496//vesicle transport along microtubule;GO:0048753//pigment granule organization;GO:0006886//intracellular protein transport gi|120300944|ref|NP_034747.2|/0/kinesin-like protein KIF13A [Mus musculus] 15369 1258 81.59 76.16666667 -0.099232581 Down 0.270177517 Hmox2 heme oxygenase 2 K00510|1|2e-169|597|mmu:15369|heme oxygenase (biliverdin-producing) [EC:1.14.14.18] - - - - 18476 892 1.42 1.783333333 0.328685461 Up 0.270168115 Pafah1b3 "platelet-activating factor acetylhydrolase, isoform 1b, subunit 3" K16795|1|2e-133|477|cge:100756174|platelet-activating factor acetylhydrolase IB subunit beta/gamma [EC:3.1.1.47] GO:0044444//cytoplasmic part GO:0046983//protein dimerization activity;GO:0016407//acetyltransferase activity GO:0006629//lipid metabolic process;GO:0007417//central nervous system development;GO:0048232//male gamete generation gi|625214213|ref|XP_007647674.1|/1.91479e-133/PREDICTED: platelet-activating factor acetylhydrolase IB subunit gamma isoform X1 [Cricetulus griseus] 64075 3463 1.406666667 1.766666667 0.328749361 Up 0.270168115 Smoc1 SPARC related modular calcium binding 1 K06826|1|8e-17|92.4|clv:102094598|nidogen (entactin) GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0043062//extracellular structure organization;GO:0001649//osteoblast differentiation;GO:0010810//regulation of cell-substrate adhesion;GO:0007423//sensory organ development;GO:0048736;GO:0007154//cell communication;GO:0043062//extracellular structure organization;GO:0001649//osteoblast differentiation;GO:0010810//regulation of cell-substrate adhesion;GO:0007423//sensory organ development;GO:0048736;GO:0007154//cell communication "gi|148670754|gb|EDL02701.1|/0/SPARC related modular calcium binding 1, isoform CRA_c, partial [Mus musculus]" 240120 2086 0.43 0.676666667 0.654108662 Up 0.270121103 Zfp119b zinc finger protein 119b K09228|1|0.0|1125|mmu:240120|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|22122835|ref|NP_666361.1|/0/zinc finger protein 119b isoform 1 [Mus musculus] 100101807 3863 6.463333333 7.213333333 0.158387696 Up 0.2701117 1700047I17Rik2 RIKEN cDNA 1700047I17 gene 2 K12400|1|3e-25|120|hgl:106007798|AP-4 complex subunit epsilon-1 - - - gi|37537562|ref|NP_082803.1|/9.16774e-89/protein FAM177A1 [Mus musculus] 12540 2096.71 74.31333333 79.64 0.099872138 Up 0.270064688 Cdc42 cell division cycle 42 K04393|1|8e-108|393|xtr:493389|cell division control protein 42 "GO:0005819//spindle;GO:0042995//cell projection;GO:0016020//membrane;GO:0012505//endomembrane system;GO:0044297//cell body;GO:0070161;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005819//spindle;GO:0042995//cell projection;GO:0016020//membrane;GO:0012505//endomembrane system;GO:0044297//cell body;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0019901//protein kinase binding;GO:0017111//nucleoside-triphosphatase activity;GO:0034190//apolipoprotein receptor binding;GO:0032550;GO:0019901//protein kinase binding;GO:0017111//nucleoside-triphosphatase activity;GO:0034190//apolipoprotein receptor binding;GO:0032550 GO:0007067//mitotic nuclear division;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007015//actin filament organization;GO:0009887//organ morphogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0043085//positive regulation of catalytic activity;GO:0045216//cell-cell junction organization;GO:0016055//Wnt signaling pathway;GO:0006461//protein complex assembly;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0031269//pseudopodium assembly;GO:0002573//myeloid leukocyte differentiation;GO:0007254//JNK cascade;GO:0001942//hair follicle development;GO:0009154//purine ribonucleotide catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0016337//single organismal cell-cell adhesion;GO:0001525//angiogenesis;GO:0042692//muscle cell differentiation;GO:0051645//Golgi localization;GO:0040023//establishment of nucleus localization;GO:0010970//transport along microtubule;GO:0006935//chemotaxis;GO:0008284//positive regulation of cell proliferation;GO:0046847//filopodium assembly;GO:0001709//cell fate determination;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0030216//keratinocyte differentiation;GO:0032388//positive regulation of intracellular transport;GO:0051130//positive regulation of cellular component organization;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0007267//cell-cell signaling;GO:0010608//posttranscriptional regulation of gene expression;GO:0032467//positive regulation of cytokinesis;GO:0006260//DNA replication;GO:0007507//heart development;GO:0043393//regulation of protein binding;GO:0009746;GO:0040007//growth;GO:0003015//heart process;GO:0007435//salivary gland morphogenesis;GO:0002064//epithelial cell development;GO:0006887//exocytosis;GO:0007265//Ras protein signal transduction;GO:0031294//lymphocyte costimulation;GO:0009894;GO:0007599//hemostasis;GO:0007067//mitotic nuclear division;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007015//actin filament organization;GO:0009887//organ morphogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0043085//positive regulation of catalytic activity;GO:0045216//cell-cell junction organization;GO:0016055//Wnt signaling pathway;GO:0006461//protein complex assembly;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0031269//pseudopodium assembly;GO:0002573//myeloid leukocyte differentiation;GO:0007254//JNK cascade;GO:0001942//hair follicle development;GO:0009154//purine ribonucleotide catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0016337//single organismal cell-cell adhesion;GO:0001525//angiogenesis;GO:0042692//muscle cell differentiation;GO:0051645//Golgi localization;GO:0040023//establishment of nucleus localization;GO:0010970//transport along microtubule;GO:0006935//chemotaxis;GO:0008284//positive regulation of cell proliferation;GO:0046847//filopodium assembly;GO:0001709//cell fate determination;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0030216//keratinocyte differentiation;GO:0032388//positive regulation of intracellular transport;GO:0051130//positive regulation of cellular component organization;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0007267//cell-cell signaling;GO:0010608//posttranscriptional regulation of gene expression;GO:0032467//positive regulation of cytokinesis;GO:0001667//ameboidal-type cell migration;GO:0006260//DNA replication;GO:0007507//heart development;GO:0043393//regulation of protein binding;GO:0009746;GO:0040007//growth;GO:0003015//heart process;GO:0007435//salivary gland morphogenesis;GO:0002064//epithelial cell development;GO:0006887//exocytosis;GO:0007265//Ras protein signal transduction;GO:0031294//lymphocyte costimulation;GO:0009894;GO:0007599//hemostasis "gi|99032068|pdb|2DFK|B/3.19193e-106/Chain B, Crystal Structure Of The Cdc42-Collybistin Ii Complex" 215449 1937 27.92666667 30.16666667 0.111311908 Up 0.270027079 Rap1b RAS related protein 1b K07836|1|6e-91|337|gja:107105721|Ras-related protein Rap-1B GO:0016020//membrane;GO:0043234//protein complex;GO:0030054//cell junction;GO:0044444//cytoplasmic part GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0031267//small GTPase binding GO:0015980//energy derivation by oxidation of organic compounds;GO:0007599//hemostasis;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0030073//insulin secretion;GO:0009154//purine ribonucleotide catabolic process;GO:0001775//cell activation;GO:0035556//intracellular signal transduction "gi|440894067|gb|ELR46625.1|/1.14404e-91/Ras-related protein Rap-1b, partial [Bos mutus]" 98985 1830 2.156666667 2.576666667 0.256702702 Up 0.269970665 Clp1 "CLP1, cleavage and polyadenylation factor I subunit" K14399|1|0.0|820|bacu:103006007|polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78] - - - - 100504561 2448 2.563333333 2.146666667 -0.25592291 Down 0.269970665 9230112J17Rik RIKEN cDNA 9230112J17 gene - - - - - 27083 1172 0.203333333 0.046666667 -2.123382416 Down 0.269895445 Xlr4b X-linked lymphocyte-regulated 4B K19528|1|2e-14|82.8|aam:106488650|synaptonemal complex protein 3 - - - gi|144226240|ref|NP_898917.2|/1.71831e-102/X-linked lymphocyte-regulated 4C [Mus musculus] 27387 2639.19 27.86666667 30.09666667 0.11106327 Up 0.269886043 Sh2d3c SH2 domain containing 3C K08889|1|1e-10|72.0|cge:100755838|tyrosine-protein kinase Fer [EC:2.7.10.2] GO:0044424;GO:0044424 GO:0030695//GTPase regulator activity;GO:0030695//GTPase regulator activity GO:0007167//enzyme linked receptor protein signaling pathway;GO:0035556//intracellular signal transduction;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0035556//intracellular signal transduction "gi|148676623|gb|EDL08570.1|/0/SH2 domain containing 3C, isoform CRA_a, partial [Mus musculus]" 353211 12512 7.55 8.383333333 0.15104735 Up 0.269839031 Prune2 prune homolog 2 (Drosophila) K18449|1|0.0|5833|mmu:353211|prune homolog 2 - - - - 14660 4731.97 8.556666667 7.73 -0.146580476 Down 0.269839031 Gls glutaminase K01425|1|0.0|1211|mmu:14660|glutaminase [EC:3.5.1.2] GO:0044429;GO:0044429 "GO:0005488//binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005488//binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0050896//response to stimulus;GO:0051260//protein homooligomerization;GO:0006541//glutamine metabolic process;GO:0001505//regulation of neurotransmitter levels;GO:0006536//glutamate metabolic process;GO:0006835//dicarboxylic acid transport;GO:0050896//response to stimulus;GO:0051260//protein homooligomerization;GO:0006541//glutamine metabolic process;GO:0001505//regulation of neurotransmitter levels;GO:0006536//glutamate metabolic process;GO:0006835//dicarboxylic acid transport gi|50510663|dbj|BAD32317.1|/0/mKIAA0838 protein [Mus musculus] 52666 2245.22 8.276666667 7.45 -0.15180943 Down 0.269839031 Arhgef25 Rho guanine nucleotide exchange factor (GEF) 25 K08810|1|6e-126|454|cmk:103183938|triple functional domain protein [EC:2.7.11.1] GO:0043292//contractile fiber;GO:0016020//membrane;GO:0043292//contractile fiber;GO:0016020//membrane GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction gi|261878525|ref|NP_001159885.1|/0/rho guanine nucleotide exchange factor 25 isoform 2 [Mus musculus] 103266 3778 2.996666667 3.486666667 0.218489831 Up 0.269839031 Tmem263 transmembrane protein 263 - GO:0031224//intrinsic component of membrane - - gi|61557491|ref|NP_001013046.1|/2.4668e-38/transmembrane protein 263 [Mus musculus] 18010 3850 7.486666667 8.313333333 0.151103537 Up 0.269839031 Neu1 neuraminidase 1 K01186|1|0.0|819|mmu:18010|sialidase-1 [EC:3.2.1.18] GO:0031982//vesicle;GO:0005764//lysosome;GO:0016020//membrane GO:0004308//exo-alpha-sialidase activity;GO:0005488//binding - gi|254939721|ref|NP_035023.3|/0/sialidase-1 precursor [Mus musculus] 102640562 1038 2.7 3.173333333 0.233039666 Up 0.269810824 LOC102640562 expressed sequence BB218582 - - - - - 106582 1502 2.746666667 3.22 0.229378852 Up 0.269810824 Nrm nurim (nuclear envelope membrane protein) - GO:0012505//endomembrane system;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0034399//nuclear periphery - - gi|19527352|ref|NP_598883.1|/1.82119e-115/nurim [Mus musculus] 57742 1356.79 10.02333333 9.076666667 -0.143127886 Down 0.269782617 Abhd1 abhydrolase domain containing 1 K13696|1|0.0|452|mmu:57742|abhydrolase domain-containing protein 1/3 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0052689//carboxylic ester hydrolase activity;GO:0052689//carboxylic ester hydrolase activity - gi|15011864|ref|NP_067279.2|/0/protein ABHD1 [Mus musculus] 625098 2959 2.226666667 1.83 -0.283041953 Down 0.269782617 Slc38a6 "solute carrier family 38, member 6" "K14993|1|0.0|813|mmu:625098|solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 6" - - - - 75284 1271 2.396666667 1.983333333 -0.273102102 Down 0.269745007 Bcdin3d BCDIN3 domain containing K15190|1|8e-08|60.8|aqu:100641837|7SK snRNA methylphosphate capping enzyme [EC:2.1.1.-] - - - - 11776 4730 29.83333333 27.62666667 -0.110863679 Down 0.269679191 Ap3d1 "adaptor-related protein complex 3, delta 1 subunit" K12396|1|0.0|1996|mmu:11776|AP-3 complex subunit delta GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0031090//organelle membrane;GO:0033267 GO:0022892//substrate-specific transporter activity GO:0001865//NK T cell differentiation;GO:0034613//cellular protein localization;GO:0019884//antigen processing and presentation of exogenous antigen;GO:0015031//protein transport;GO:0048489//synaptic vesicle transport;GO:0032119//sequestering of zinc ion;GO:0008088//axo-dendritic transport;GO:0000041//transition metal ion transport;GO:0010256//endomembrane system organization gi|6671565|ref|NP_031486.1|/0/AP-3 complex subunit delta-1 [Mus musculus] 54354 3230.94 0.736666667 1.026666667 0.478883981 Up 0.269603972 Rassf5 Ras association (RalGDS/AF-6) domain family member 5 K08015|1|0.0|740|mmu:54354|Ras association domain-containing protein 5 - - - - 100628599 84 0.096666667 0.28 1.534336428 Up 0.269575764 Mir5130 microRNA 5130 - - - - - 223693 3239.23 28.05666667 30.24333333 0.108273541 Up 0.269509948 Tmem184b transmembrane protein 184b K14360|1|3e-08|63.5|sko:100372211|organic solute transporter subunit alpha GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148672706|gb|EDL04653.1|/0/RIKEN cDNA 4732495E13, isoform CRA_b, partial [Mus musculus]" 232566 1027 2.54 2.99 0.235316987 Up 0.269444131 Amn1 antagonist of mitotic exit network 1 K10268|1|5e-25|117|ola:101160411|F-box and leucine-rich repeat protein 2/20 - - - "gi|148678814|gb|EDL10761.1|/1.93888e-154/mCG17791, isoform CRA_a, partial [Mus musculus]" 75710 3752 2.94 2.493333333 -0.237740386 Down 0.269444131 Rbm12 RNA binding motif protein 12 K14947|1|5e-23|113|hmg:100203163|epithelial splicing regulatory protein 1/2 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding - "gi|148674224|gb|EDL06171.1|/0/mCG5227, isoform CRA_a [Mus musculus]" 67554 1706 2.486666667 2.933333333 0.238327893 Up 0.269444131 Slc25a30 "solute carrier family 25, member 30" "K15106|1|1e-165|585|mmu:67554|solute carrier family 25 (mitochondrial carrier), member 14/30" GO:0019866//organelle inner membrane;GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane - GO:0044765//single-organism transport;GO:0044763 gi|13385736|ref|NP_080508.1|/1.12377e-164/kidney mitochondrial carrier protein 1 [Mus musculus] 232987 1058 5.256666667 5.923333333 0.172261021 Up 0.269397119 B9d2 B9 protein domain 2 K16745|1|3e-104|380|mmu:232987|B9 domain-containing protein 2 GO:0005815//microtubule organizing center;GO:0005930//axoneme;GO:0035869//ciliary transition zone GO:0015631//tubulin binding GO:0010927 gi|26024311|ref|NP_742160.1|/2.76933e-103/B9 domain-containing protein 2 [Mus musculus] 74245 2906 1.633333333 1.286666667 -0.344180902 Down 0.269387717 Ctbs "chitobiase, di-N-acetyl-" K12310|1|0.0|729|mmu:74245|Di-N-acetylchitobiase [EC:3.2.1.-] GO:0000323//lytic vacuole;GO:0000323//lytic vacuole "GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds" GO:0009311//oligosaccharide metabolic process;GO:0006026;GO:0009311//oligosaccharide metabolic process;GO:0006026 gi|654821949|ref|NP_001280601.1|/0/di-N-acetylchitobiase isoform 1 precursor [Mus musculus] 245643 1401 0.54 0.31 -0.800691192 Down 0.269350107 Frmpd3 FERM and PDZ domain containing 3 - GO:0043232 - - gi|755566200|ref|XP_011246044.1|/5.18145e-85/PREDICTED: FERM and PDZ domain containing 3 isoform X1 [Mus musculus] 215090 2751 0.143333333 0.33 1.203091865 Up 0.26928429 Maneal "mannosidase, endo-alpha-like" "K15538|1|5e-177|624|dre:566679|glycoprotein endo-alpha-1,2-mannosidase [EC:3.2.1.130]" GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity - "gi|56090560|ref|NP_001007574.1|/0/glycoprotein endo-alpha-1,2-mannosidase-like protein precursor [Mus musculus]" 68294 1903 4.216666667 4.796666667 0.185929207 Up 0.269265486 Mfsd10 major facilitator superfamily domain containing 10 "K13506|1|6e-21|105|tsp:Tsp_00306|glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15];K08216|2|6e-07|58.5|rno:293686|MFS transporter, OCT family, solute carrier family 22 (organic anion transporter), member 20;K08214|5|2e-06|57.0|tad:TRIADDRAFT_58186|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 18" GO:0031224//intrinsic component of membrane - GO:0012501//programmed cell death;GO:0051234//establishment of localization "gi|148705514|gb|EDL37461.1|/0/RIKEN cDNA 0610009O03, isoform CRA_a, partial [Mus musculus]" 57764 2411 4.16 4.74 0.188303531 Up 0.269265486 Ntn4 netrin 4 K06845|1|0.0|1280|mmu:57764|netrin 4 GO:0005578//proteinaceous extracellular matrix GO:0043236//laminin binding GO:0035426//extracellular matrix-cell signaling;GO:0042551//neuron maturation gi|226442874|ref|NP_067295.2|/0/netrin-4 precursor [Mus musculus] 27223 9652 4.636666667 4.053333333 -0.193979191 Down 0.269265486 Trp53bp1 transformation related protein 53 binding protein 1 K16571|1|3e-30|138|oaa:100091557|gamma-tubulin complex component 4 - - - gi|160333077|ref|NP_038763.3|/0/tumor suppressor p53-binding protein 1 isoform a [Mus musculus] 68035 1701 28.12333333 30.29 0.107073977 Up 0.269199669 Rbm42 RNA binding motif protein 42 K13201|1|1e-11|73.9|smm:Smp_166190|nucleolysin TIA-1/TIAR - - - - 30055 1225 30.62666667 28.46 -0.105852694 Down 0.269199669 Timm13 translocase of inner mitochondrial membrane 13 K17781|1|1e-39|166|rno:252928|mitochondrial import inner membrane translocase subunit TIM13 GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding GO:0045184//establishment of protein localization gi|12833472|dbj|BAB22536.1|/1.03407e-38/unnamed protein product [Mus musculus] 380686 1569 1.67 2.053333333 0.298119747 Up 0.269162059 Cnrip1 cannabinoid receptor interacting protein 1 - - - - - 67382 5279.9 8.216666667 7.396666667 -0.151677979 Down 0.26912445 Brd3 bromodomain containing 3 K11721|1|0.0|870|mmu:67382|bromodomain-containing protein 3 - GO:0042393//histone binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter" gi|165972335|ref|NP_001107046.1|/0/bromodomain-containing protein 3 isoform 1 [Mus musculus] 54006 2128.17 7.476666667 8.3 0.150716122 Up 0.26912445 Deaf1 deformed epidermal autoregulatory factor 1 (Drosophila) "K10053|1|3e-13|80.1|lcm:102365186|runt-related transcription factor 1; translocated to, 1" GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0001501//skeletal system development;GO:0014020;GO:0033598//mammary gland epithelial cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001501//skeletal system development;GO:0014020;GO:0033598//mammary gland epithelial cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001501//skeletal system development;GO:0014020;GO:0033598//mammary gland epithelial cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001501//skeletal system development;GO:0014020;GO:0033598//mammary gland epithelial cell proliferation;GO:0006366//transcription from RNA polymerase II promoter gi|530719528|ref|NP_001269005.1|/1.59945e-167/deformed epidermal autoregulatory factor 1 homolog isoform 4 precursor [Mus musculus] 57339 4809 6.09 6.826666667 0.164739081 Up 0.269068036 Jph1 junctophilin 1 K19530|1|0.0|1142|mmu:57339|junctophilin GO:0033017//sarcoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane;GO:0031674//I band GO:0005198//structural molecule activity GO:0048513//animal organ development "gi|148682412|gb|EDL14359.1|/0/junctophilin 1, partial [Mus musculus]" 64945 3746.54 6.14 6.883333333 0.16486872 Up 0.269068036 Cldn12 claudin 12 K06087|1|3e-07|60.8|mze:101479976|claudin GO:0043296//apical junction complex;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex;GO:0044464;GO:0031224//intrinsic component of membrane - - "gi|148682691|gb|EDL14638.1|/2.49936e-139/claudin 12, isoform CRA_a, partial [Mus musculus]" 381605 4305 1.14 0.84 -0.440572591 Down 0.269030426 Tbc1d2 "TBC1 domain family, member 2" K20165|1|0.0|1578|mmu:381605|TBC1 domain family member 2A GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle GO:0008289//lipid binding;GO:0050839//cell adhesion molecule binding - gi|111038126|ref|NP_941066.3|/0/TBC1 domain family member 2A [Mus musculus] 13134 5310 1.126666667 0.83 -0.440877504 Down 0.269030426 Dach1 dachshund 1 (Drosophila) K19375|1|5e-48|196|smm:Smp_180990|HSPB1-associated protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0000983//transcription factor activity, RNA polymerase II core promoter sequence-specific;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0000983//transcription factor activity, RNA polymerase II core promoter sequence-specific" "GO:0006366//transcription from RNA polymerase II promoter;GO:0045137//development of primary sexual characteristics;GO:0045892//negative regulation of transcription, DNA-templated;GO:0008285//negative regulation of cell proliferation;GO:0007631//feeding behavior;GO:0016477//cell migration;GO:0006366//transcription from RNA polymerase II promoter;GO:0045137//development of primary sexual characteristics;GO:0045892//negative regulation of transcription, DNA-templated;GO:0008285//negative regulation of cell proliferation;GO:0007631//feeding behavior;GO:0016477//cell migration" gi|4322569|gb|AAD16098.1|/0/dachshund variant 2 [Mus musculus] 27369 1103.79 16.82 18.26333333 0.118772397 Up 0.268983414 Dguok deoxyguanosine kinase K00904|1|9e-148|525|mmu:27369|deoxyguanosine kinase [EC:2.7.1.113] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0032550;GO:0019136//deoxynucleoside kinase activity;GO:0032550;GO:0019136//deoxynucleoside kinase activity GO:0042278//purine nucleoside metabolic process;GO:0006464//cellular protein modification process;GO:0010975//regulation of neuron projection development;GO:0009151;GO:0042278//purine nucleoside metabolic process;GO:0006464//cellular protein modification process;GO:0010975//regulation of neuron projection development;GO:0009151 "gi|247269607|ref|NP_038792.2|/7.5274e-147/deoxyguanosine kinase, mitochondrial isoform 1 [Mus musculus]" 69617 3547 17.96 16.51666667 -0.120864793 Down 0.268983414 Pitrm1 pitrilysin metallepetidase 1 K06972|1|0.0|2116|mmu:69617|presequence protease [EC:3.4.24.-] GO:0044429 GO:0004175//endopeptidase activity;GO:0043169//cation binding GO:0019538//protein metabolic process "gi|21699068|ref|NP_660113.1|/0/presequence protease, mitochondrial precursor [Mus musculus]" 22256 1911.93 15.96666667 17.40333333 0.124300503 Up 0.268983414 Ung uracil DNA glycosylase K03648|1|5e-150|533|mmu:22256|uracil-DNA glycosylase [EC:3.2.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0019104//DNA N-glycosylase activity;GO:0050263//ribosylpyrimidine nucleosidase activity;GO:0019104//DNA N-glycosylase activity;GO:0050263//ribosylpyrimidine nucleosidase activity GO:0006281//DNA repair;GO:0006915//apoptotic process;GO:0002566//somatic diversification of immune receptors via somatic mutation;GO:0002562;GO:0006281//DNA repair;GO:0006915//apoptotic process;GO:0002566//somatic diversification of immune receptors via somatic mutation;GO:0002562 gi|101943608|ref|NP_001035781.1|/9.12586e-174/uracil-DNA glycosylase isoform a [Mus musculus] 16592 950 27.66 29.81333333 0.108156531 Up 0.268964609 Fabp5 "fatty acid binding protein 5, epidermal" "K08754|1|7e-66|253|mmu:16592|fatty acid-binding protein 5, epidermal" GO:0044424;GO:0044424;GO:0044424 GO:0008289//lipid binding;GO:0008289//lipid binding;GO:0008289//lipid binding GO:0019318//hexose metabolic process;GO:0008645//hexose transport;GO:0046165;GO:0006950//response to stress;GO:0019318//hexose metabolic process;GO:0008645//hexose transport;GO:0046165;GO:0006950//response to stress;GO:0019318//hexose metabolic process;GO:0008645//hexose transport;GO:0046165;GO:0006950//response to stress gi|148703492|gb|EDL35439.1|/1.92312e-66/mCG22278 [Mus musculus] 630146 3254 0.24 0.073333333 -1.710493383 Down 0.268936402 Cd101 CD101 antigen "K06522|1|0.0|1989|mmu:630146|immunoglobulin superfamily, member 2/3" GO:0031224//intrinsic component of membrane - - gi|268835535|ref|NP_001161378.1|/0/immunoglobulin superfamily member 2 precursor [Mus musculus] 56772 2514 4.706666667 5.326666667 0.17852732 Up 0.268879988 Mllt11 "myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11" K11421|1|1e-08|65.1|gga:395847|histone-lysine N-methyltransferase SETDB1 [EC:2.1.1.43] GO:0044464 - "GO:0035556//intracellular signal transduction;GO:0006915//apoptotic process;GO:0010822//positive regulation of mitochondrion organization;GO:0007166//cell surface receptor signaling pathway;GO:0032846;GO:0006351//transcription, DNA-templated" gi|9910124|ref|NP_064298.1|/7.94928e-35/protein AF1q [Mus musculus] 414094 770 0.593333333 0.863333333 0.541074857 Up 0.268795367 Dgkeos "diacylglycerol kinase, epsilon, opposite strand" - - - - gi|148683924|gb|EDL15871.1|/2.60089e-82/RIKEN cDNA A930013B10 [Mus musculus] 68204 597 0.34 0.15 -1.180572246 Down 0.268776562 2900060B14Rik RIKEN cDNA 2900060B14 gene - - - - gi|74146876|dbj|BAE41397.1|/3.39359e-07/unnamed protein product [Mus musculus] 636741 1740 0.346666667 0.153333333 -1.176877762 Down 0.268776562 Zfp964 zinc finger protein 964 K09228|1|0.0|1027|mmu:636741|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|294661871|ref|NP_001170998.1|/0/zinc finger-like protein [Mus musculus] 66191 1404 17.16333333 18.59333333 0.115455664 Up 0.268767159 Ier3ip1 immediate early response 3 interacting protein 1 - GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0006915//apoptotic process gi|13384796|ref|NP_079685.1|/3.08981e-37/immediate early response 3-interacting protein 1 precursor [Mus musculus] 73296 4937 2.693333333 2.263333333 -0.250943719 Down 0.268738952 Rhobtb3 Rho-related BTB domain containing 3 K07869|1|0.0|1242|mmu:73296|Rho-related BTB domain-containing protein 3 GO:0043231//intracellular membrane-bounded organelle GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017016//Ras GTPase binding GO:0016192//vesicle-mediated transport;GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process gi|37360132|dbj|BAC98044.1|/0/mKIAA0878 protein [Mus musculus] 18793 1508 2.736666667 2.306666667 -0.246610184 Down 0.268738952 Plaur "plasminogen activator, urokinase receptor" "K03985|1|1e-172|608|mmu:18793|plasminogen activator, urokinase receptor" - - - - 23948 4477 1.04 1.36 0.387023123 Up 0.268673136 Mmp17 matrix metallopeptidase 17 K07997|1|0.0|1070|mmu:23948|matrix metalloproteinase-17 (membrane-inserted) [EC:3.4.24.-] GO:0031224//intrinsic component of membrane;GO:0031012//extracellular matrix "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process gi|31543257|ref|NP_035976.3|/0/matrix metalloproteinase-17 preproprotein [Mus musculus] 68169 4684 0.323333333 0.553333333 0.775126589 Up 0.268597916 Ndnf neuron-derived neurotrophic factor - - - - - 216441 2215 10.02 9.09 -0.140530309 Down 0.268541502 Slc26a10 "solute carrier family 26, member 10" "K14707|1|0.0|1014|mmu:216441|solute carrier family 26, member 10" - - - gi|260593700|ref|NP_808283.2|/0/solute carrier family 26 member 10 [Mus musculus] 226442 5271.2 1.463333333 1.133333333 -0.368686193 Down 0.268428674 Zfp281 zinc finger protein 281 K09228|1|1e-28|132|gja:107122611|KRAB domain-containing zinc finger protein GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003712//transcription cofactor activity;GO:0044212//transcription regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003712//transcription cofactor activity;GO:0044212//transcription regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0010171//body morphogenesis;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0010171//body morphogenesis;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated" gi|29244048|ref|NP_808311.1|/0/zinc finger protein 281 [Mus musculus] 246177 3307 1.126666667 1.46 0.373907623 Up 0.268428674 Myo1g myosin IG K10356|1|0.0|2034|mmu:246177|myosin I GO:0016020//membrane;GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 - "gi|148708651|gb|EDL40598.1|/0/myosin IG, partial [Mus musculus]" 207278 4360 4.163333333 3.623333333 -0.200421537 Down 0.268400466 Fchsd2 FCH and double SH3 domains 2 K20125|1|0.0|1382|ngi:103749841|F-BAR and double SH3 domains protein - - - - 66248 1471 7.176666667 7.99 0.154881589 Up 0.268381662 Alg5 asparagine-linked glycosylation 5 (dolichyl-phosphate beta-glucosyltransferase) K00729|1|2e-172|608|mmu:66248|dolichyl-phosphate beta-glucosyltransferase [EC:2.4.1.117] - - - - 18230 2728 7.256666667 8.07 0.153261672 Up 0.268381662 Nxn nucleoredoxin K17609|1|0.0|766|mmu:18230|nucleoredoxin [EC:1.8.1.8] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0005488//binding;GO:0016668//oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor;GO:0016209//antioxidant activity" GO:0048869//cellular developmental process;GO:0048731//system development;GO:0016055//Wnt signaling pathway;GO:0044710;GO:0016567//protein ubiquitination gi|6679160|ref|NP_032776.1|/0/nucleoredoxin [Mus musculus] 12400 2911.41 7.513333333 8.326666667 0.148285961 Up 0.268381662 Cbfb core binding factor beta - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0001503//ossification;GO:0021700//developmental maturation;GO:0002521//leukocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001503//ossification;GO:0021700//developmental maturation;GO:0002521//leukocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001503//ossification;GO:0021700//developmental maturation;GO:0002521//leukocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001503//ossification;GO:0021700//developmental maturation;GO:0002521//leukocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter "gi|148679302|gb|EDL11249.1|/2.50166e-96/core binding factor beta, isoform CRA_a, partial [Mus musculus]" 107239 3968 8.503333333 7.69 -0.145044895 Down 0.268381662 Carns1 carnosine synthase 1 K14755|1|0.0|1683|mmu:107239|carnosine synthase [EC:6.3.2.11] - GO:0043169//cation binding - "gi|148701080|gb|EDL33027.1|/0/mCG3875, partial [Mus musculus]" 27886 2836 6.953333333 6.22 -0.160790172 Down 0.268344052 Dgcr14 DiGeorge syndrome critical region gene 14 K13118|1|0.0|718|mmu:27886|protein DGCR14 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex - GO:0006396//RNA processing;GO:0000377;GO:0048731//system development "gi|148665077|gb|EDK97493.1|/0/expressed sequence 2 embryonic lethal, isoform CRA_b, partial [Mus musculus]" 60504 2607 6.05 6.78 0.164350131 Up 0.268344052 Il21r interleukin 21 receptor K05075|1|0.0|971|mmu:60504|interleukin 21 receptor GO:0031224//intrinsic component of membrane GO:0004896//cytokine receptor activity GO:0019221//cytokine-mediated signaling pathway gi|11230786|ref|NP_068687.1|/0/interleukin-21 receptor precursor [Mus musculus] 12566 2331.38 5.393333333 6.05 0.16575794 Up 0.268325247 Cdk2 cyclin-dependent kinase 2 K02206|1|0.0|711|mmu:12566|cyclin-dependent kinase 2 [EC:2.7.11.22] GO:0044427;GO:0015630//microtubule cytoskeleton;GO:0016604//nuclear body;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0000803//sex chromosome;GO:0000803//sex chromosome;GO:0043234//protein complex;GO:0016604//nuclear body;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part;GO:0044427 GO:0032550;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0043169//cation binding;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0005515//protein binding;GO:0043169//cation binding "GO:0006351//transcription, DNA-templated;GO:0016458//gene silencing;GO:0032868//response to insulin;GO:0030001//metal ion transport;GO:0008283//cell proliferation;GO:0046683//response to organophosphorus;GO:0006468//protein phosphorylation;GO:0009628//response to abiotic stimulus;GO:0033554//cellular response to stress;GO:0000087//mitotic M phase;GO:0006270//DNA replication initiation;GO:0034614//cellular response to reactive oxygen species;GO:0032868//response to insulin;GO:0009628//response to abiotic stimulus;GO:0044773//mitotic DNA damage checkpoint;GO:0006351//transcription, DNA-templated;GO:0030001//metal ion transport;GO:0000087//mitotic M phase;GO:0016458//gene silencing;GO:0044772//mitotic cell cycle phase transition;GO:0051319;GO:0051320;GO:0007599//hemostasis;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006270//DNA replication initiation;GO:0007264//small GTPase mediated signal transduction;GO:0046683//response to organophosphorus;GO:0043627//response to estrogen;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010038//response to metal ion;GO:0008283//cell proliferation;GO:0007098//centrosome cycle;GO:0097305//response to alcohol;GO:0006468//protein phosphorylation;GO:0009887//organ morphogenesis" gi|7949020|ref|NP_058036.1|/2.59402e-170/cyclin-dependent kinase 2 isoform 2 [Mus musculus] 57438 2719 5.94 5.283333333 -0.169014496 Down 0.268325247 7-Mar membrane-associated ring finger (C3HC4) 7 K10662|1|0.0|1066|mmu:57438|E3 ubiquitin-protein ligase MARCH7 [EC:2.3.2.27] - GO:0046914//transition metal ion binding;GO:0003824//catalytic activity - gi|10181210|ref|NP_065600.1|/0/E3 ubiquitin-protein ligase MARCH7 [Mus musculus] 232801 2109 0.68 0.96 0.497499659 Up 0.26829704 Lilra5 "leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5" K06512|1|4e-165|584|mmu:232801|leukocyte immunoglobulin-like receptor - - - gi|156766061|ref|NP_001074708.2|/3.28728e-164/leukocyte immunoglobulin-like receptor precursor [Mus musculus] 235169 2289.57 29.61333333 27.51 -0.106290753 Down 0.268268833 Foxred1 FAD-dependent oxidoreductase domain containing 1 K18166|1|0.0|939|mmu:235169|FAD-dependent oxidoreductase domain-containing protein 1 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0044710;GO:0044710;GO:0044710 "gi|148693434|gb|EDL25381.1|/0/FAD-dependent oxidoreductase domain containing 1, isoform CRA_a, partial [Mus musculus]" 19116 10328 0.613333333 0.376666667 -0.703382994 Down 0.268268833 Prlr prolactin receptor K05081|1|0.0|1142|mmu:19116|prolactin receptor GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane GO:0004896//cytokine receptor activity;GO:0043169//cation binding;GO:0042277//peptide binding;GO:0019900//kinase binding;GO:0004896//cytokine receptor activity;GO:0043169//cation binding;GO:0042277//peptide binding;GO:0019900//kinase binding;GO:0004896//cytokine receptor activity;GO:0043169//cation binding;GO:0042277//peptide binding;GO:0019900//kinase binding GO:0030879//mammary gland development;GO:0007155//cell adhesion;GO:0003006//developmental process involved in reproduction;GO:0007589//body fluid secretion;GO:0009755//hormone-mediated signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030855//epithelial cell differentiation;GO:0030879//mammary gland development;GO:0007155//cell adhesion;GO:0003006//developmental process involved in reproduction;GO:0007589//body fluid secretion;GO:0009755//hormone-mediated signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030855//epithelial cell differentiation;GO:0030879//mammary gland development;GO:0007155//cell adhesion;GO:0003006//developmental process involved in reproduction;GO:0007589//body fluid secretion;GO:0009755//hormone-mediated signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030855//epithelial cell differentiation gi|359339023|ref|NP_001240710.1|/0/prolactin receptor isoform 2 precursor [Mus musculus] 233895 2325 27.77 29.86666667 0.105009054 Up 0.268268833 Prr14 proline rich 14 "K01106|1|5e-07|59.3|oas:101103674|inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56]" - - - "gi|148685593|gb|EDL17540.1|/0/proline rich 14, isoform CRA_d, partial [Mus musculus]" 77552 1190 3.76 3.246666667 -0.21177339 Down 0.268203016 Shisa4 shisa family member 4 K10135|1|1e-14|83.6|lcm:102352894|scotin GO:0031224//intrinsic component of membrane - - "gi|148707634|gb|EDL39581.1|/1.77399e-88/transmembrane protein 58, partial [Mus musculus]" 12483 3972 3.663333333 3.156666667 -0.214755055 Down 0.268203016 Cd22 CD22 antigen K06467|1|0.0|1723|mmu:12483|CD22 antigen GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane GO:0038023//signaling receptor activity;GO:0005488//binding;GO:0038023//signaling receptor activity;GO:0038023//signaling receptor activity;GO:0038023//signaling receptor activity GO:0007165//signal transduction;GO:0022610;GO:0007165//signal transduction;GO:0007165//signal transduction;GO:0007165//signal transduction;GO:0022610 gi|112807203|ref|NP_001036782.1|/0/B-cell receptor CD22 precursor [Mus musculus] 208431 8167 3.716666667 3.206666667 -0.212934911 Down 0.268203016 Shroom4 shroom family member 4 K18625|1|0.0|2584|mmu:208431|protein Shroom - - - - 67287 2576.1 13.21333333 12.11 -0.125795597 Down 0.268174809 Parp6 "poly (ADP-ribose) polymerase family, member 6" K15258|1|0.0|860|mmu:67287|poly [ADP-ribose] polymerase 6/8 [EC:2.4.2.30] - "GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups" - gi|112807189|ref|NP_084198.2|/0/poly [ADP-ribose] polymerase 6 isoform 2 [Mus musculus] 23955 4195.53 1.25 1.59 0.347098671 Up 0.268127797 Nek4 NIMA (never in mitosis gene a)-related expressed kinase 4 K08857|1|0.0|1396|mmu:23955|NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] - - - - 68515 2325 25.98 28.06333333 0.11128495 Up 0.26809959 Myadml2 myeloid-associated differentiation marker-like 2 K00286|1|9e-128|460|bacu:103012704|pyrroline-5-carboxylate reductase [EC:1.5.1.2] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|325651911|ref|NP_001191749.1|/1.10574e-76/myeloid-associated differentiation marker-like protein 2 isoform 2 [Mus musculus] 12741 1420 27.42666667 29.50333333 0.105298669 Up 0.26809959 Cldn5 claudin 5 K06087|1|2e-89|332|mmu:12741|claudin GO:0043296//apical junction complex;GO:0033267;GO:0031224//intrinsic component of membrane;GO:0043218//compact myelin GO:0005515//protein binding GO:0016337//single organismal cell-cell adhesion;GO:0008366//axon ensheathment gi|31980735|ref|NP_038833.2|/1.33816e-88/claudin-5 [Mus musculus] 22154 2645 64.21666667 68.63333333 0.095961644 Up 0.268071383 Tubb5 "tubulin, beta 5 class I" K07375|1|0.0|831|chx:102168953|tubulin beta - - - - 74490 2179 2.94 3.423333333 0.219585621 Up 0.268061981 Mamstr MEF2 activating motif and SAP domain containing transcriptional regulator - - - - gi|294345434|ref|NP_766006.2|/5.30792e-133/MEF2-activating motif and SAP domain-containing transcriptional regulator [Mus musculus] 67451 2891 66.12666667 61.71333333 -0.099649958 Down 0.268061981 Pkp2 plakophilin 2 K12642|1|0.0|1521|mmu:67451|plakophilin 2 GO:0044291//cell-cell contact zone;GO:0070161;GO:0043234//protein complex GO:0019901//protein kinase binding;GO:0032403//protein complex binding GO:0002027//regulation of heart rate;GO:0007267//cell-cell signaling;GO:0045596//negative regulation of cell differentiation;GO:0007155//cell adhesion;GO:0008283//cell proliferation;GO:0003208//cardiac ventricle morphogenesis;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0034331;GO:0086065//cell communication involved in cardiac conduction;GO:0002934//desmosome organization;GO:0070830//bicellular tight junction assembly;GO:0016477//cell migration gi|21312960|ref|NP_080439.1|/0/plakophilin-2 [Mus musculus] 69225 1336.82 25.27333333 27.34333333 0.113573172 Up 0.267996164 Carkd carbohydrate kinase domain containing K17757|1|1e-178|628|mmu:69225|ATP-dependent NAD(P)H-hydrate dehydratase [EC:4.2.1.93] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016836//hydro-lyase activity;GO:0032550;GO:0016836//hydro-lyase activity;GO:0032550;GO:0016836//hydro-lyase activity;GO:0032550 GO:0019362;GO:0019362;GO:0019362 gi|298676450|ref|NP_081271.2|/0/ATP-dependent (S)-NAD(P)H-hydrate dehydratase isoform 1 [Mus musculus] 66268 692 26.29666667 28.36333333 0.109147155 Up 0.267996164 Pigyl "phosphatidylinositol glycan anchor biosynthesis, class Y-like" "K11001|1|3e-38|160|cge:100752710|phosphatidylinositol glycan anchor biosynthesis, class Y" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0006497//protein lipidation gi|148693315|gb|EDL25262.1|/8.83387e-41/RIKEN cDNA 1810008A14 [Mus musculus] 57869 3539 4.13 4.703333333 0.1875418 Up 0.267949152 Adck2 aarF domain containing kinase 2 K08869|1|0.0|1110|mmu:57869|aarF domain-containing kinase GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|30725855|ref|NP_849204.1|/0/uncharacterized aarF domain-containing protein kinase 2 [Mus musculus] 66154 969 58.83 63.20333333 0.103448612 Up 0.267920945 Tmem14c transmembrane protein 14C - GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane - GO:0006779//porphyrin-containing compound biosynthetic process gi|512971254|ref|XP_004847757.1|/2.12933e-43/PREDICTED: transmembrane protein 14C isoform X1 [Heterocephalus glaber] 360216 2127 10.26 9.34 -0.135536276 Down 0.267911542 Zranb1 "zinc finger, RAN-binding domain containing 1" K11862|1|0.0|1414|rno:100360606|ubiquitin thioesterase ZRANB1 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle GO:0031593//polyubiquitin binding;GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding;GO:0019783//ubiquitin-like protein-specific protease activity GO:0016055//Wnt signaling pathway;GO:0006996//organelle organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0048870//cell motility;GO:0000902//cell morphogenesis;GO:0016579//protein deubiquitination gi|46409652|ref|NP_997185.1|/0/ubiquitin thioesterase Zranb1 [Mus musculus] 66361 1646 9.21 10.13333333 0.137835762 Up 0.267911542 Zfand1 "zinc finger, AN1-type domain 1" K07059|1|3e-123|444|hsa:79752|uncharacterized protein - GO:0046914//transition metal ion binding - gi|31982674|ref|NP_079788.2|/3.36774e-142/AN1-type zinc finger protein 1 [Mus musculus] 12558 4858 67.56 63.23 -0.095560109 Down 0.267817519 Cdh2 cadherin 2 "K06736|1|0.0|1587|mmu:12558|cadherin 2, type 1, N-cadherin" - - - - 319162 508 11.93333333 13.02333333 0.126101668 Up 0.267808116 Hist3h2a "histone cluster 3, H2a" K11251|1|7e-55|214|ocu:100348744|histone H2A GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|676263355|gb|KFO20085.1|/4.80312e-54/histone H2A type 3 [Fukomys damarensis] 380712 1160.37 7.266666667 8.066666667 0.150678912 Up 0.267676483 Tlcd2 TLC domain containing 2 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|47059147|ref|NP_081525.1|/1.36766e-149/TLC domain-containing protein 2 isoform 1 [Mus musculus] 53380 1456 5.176666667 4.566666667 -0.180881937 Down 0.26766708 Psmd10 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 10" K06694|1|8e-129|462|mmu:53380|26S proteasome non-ATPase regulatory subunit 10 GO:0005856//cytoskeleton;GO:0005838//proteasome regulatory particle;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0005838//proteasome regulatory particle;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0005515//protein binding "GO:0006915//apoptotic process;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0010823//negative regulation of mitochondrion organization;GO:0016567//protein ubiquitination;GO:0016049//cell growth;GO:0043248//proteasome assembly;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006366//transcription from RNA polymerase II promoter;GO:0031331;GO:0000165//MAPK cascade;GO:0006915//apoptotic process;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0010823//negative regulation of mitochondrion organization;GO:0016567//protein ubiquitination;GO:0016049//cell growth;GO:0043248//proteasome assembly;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006366//transcription from RNA polymerase II promoter;GO:0031331;GO:0000165//MAPK cascade" gi|31980811|ref|NP_058579.2|/1.33955e-106/26S proteasome non-ATPase regulatory subunit 10 isoform 1 [Mus musculus] 54725 4354 0.156666667 0.346666667 1.145850866 Up 0.26766708 Cadm1 cell adhesion molecule 1 K06781|1|0.0|719|mmu:54725|cell adhesion molecule 1 GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0044459;GO:0030136//clathrin-coated vesicle GO:0019904//protein domain specific binding;GO:0042802//identical protein binding GO:0001501//skeletal system development;GO:0050663//cytokine secretion;GO:0012501//programmed cell death;GO:0000902//cell morphogenesis;GO:0016337//single organismal cell-cell adhesion;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0048232//male gamete generation;GO:0007399//nervous system development gi|899138174|ref|NP_001297770.1|/0/cell adhesion molecule 1 isoform e precursor [Mus musculus] 14561 1811 0.633333333 0.393333333 -0.687212559 Down 0.267638873 Gdf11 growth differentiation factor 11 K05497|1|0.0|704|pale:102898082|growth differentiation factor 8/11 GO:0044421 GO:0005102//receptor binding GO:0035295//tube development;GO:0009888//tissue development;GO:0043010//camera-type eye development;GO:0009952//anterior/posterior pattern specification;GO:0001822//kidney development;GO:0009653//anatomical structure morphogenesis;GO:0021700//developmental maturation;GO:0008283//cell proliferation;GO:0030182//neuron differentiation gi|6649914|gb|AAF21630.1|AF028333_1/0/growth/differentiation factor-11 [Homo sapiens] 625054 2057 2.073333333 2.486666667 0.26226105 Up 0.267610666 Gm6548 eukaryotic translation elongation factor 1 alpha 1 pseudogene K03231|1|0.0|438|oas:105613550|elongation factor 1-alpha GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008135//translation factor activity, RNA binding;GO:0019900//kinase binding" "GO:0006351//transcription, DNA-templated;GO:0006412//translation;GO:0006915//apoptotic process;GO:0009154//purine ribonucleotide catabolic process" gi|803119291|ref|XP_012040812.1|/0/PREDICTED: elongation factor 1-alpha 1-like isoform X1 [Ovis aries] 17217 3589 2.06 2.473333333 0.263812349 Up 0.267610666 Mcm4 minichromosome maintenance complex component 4 K02212|1|0.0|1623|mmu:17217|DNA replication licensing factor MCM4 [EC:3.6.4.12] GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0003678//DNA helicase activity;GO:0032550;GO:0043566//structure-specific DNA binding GO:0044763;GO:0006261//DNA-dependent DNA replication gi|255918149|ref|NP_032591.3|/0/DNA replication licensing factor MCM4 [Mus musculus] 19707 2557.89 16.49 17.87666667 0.116486354 Up 0.267591861 Reps1 RalBP1 associated Eps domain containing protein K20068|1|0.0|1346|mmu:19707|RalBP1-associated Eps domain-containing protein GO:0012505//endomembrane system;GO:0016020//membrane GO:0019904//protein domain specific binding GO:0006897//endocytosis gi|161484652|ref|NP_001104535.1|/0/ralBP1-associated Eps domain-containing protein 1 isoform 2 [Mus musculus] 97775 3452 0.723333333 0.47 -0.62199988 Down 0.267544849 D930048N14Rik RIKEN cDNA D930048N14 gene - - - - - 214779 2300 0.493333333 0.273333333 -0.851901361 Down 0.267526045 Zfp879 zinc finger protein 879 K09228|1|0.0|1191|mmu:214779|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|27734192|ref|NP_775563.1|/0/zinc finger protein 879 isoform 1 [Mus musculus] 70103 895.09 60.95333333 65.15 0.09606006 Up 0.267479033 Znhit1 "zinc finger, HIT domain containing 1" K11663|1|3e-67|258|rno:100360077|zinc finger HIT domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0019899//enzyme binding;GO:0043169//cation binding;GO:0019899//enzyme binding;GO:0043169//cation binding;GO:0019899//enzyme binding GO:0016575//histone deacetylation;GO:0042098//T cell proliferation;GO:0010948//negative regulation of cell cycle process;GO:0016575//histone deacetylation;GO:0042098//T cell proliferation;GO:0010948//negative regulation of cell cycle process;GO:0016575//histone deacetylation;GO:0042098//T cell proliferation;GO:0010948//negative regulation of cell cycle process "gi|148687347|gb|EDL19294.1|/5.27843e-95/zinc finger, HIT domain containing 1, isoform CRA_c, partial [Mus musculus]" 57317 2254 26.62666667 28.66 0.106166778 Up 0.26746963 Srsf4 serine/arginine-rich splicing factor 4 "K12893|1|2e-79|299|pale:102898727|splicing factor, arginine/serine-rich 4/5/6" GO:0016604//nuclear body GO:0003676//nucleic acid binding;GO:0036094//small molecule binding "GO:0000398//mRNA splicing, via spliceosome;GO:0006405//RNA export from nucleus;GO:0006366//transcription from RNA polymerase II promoter" gi|940753759|ref|XP_014318511.1|/9.00571e-86/PREDICTED: serine/arginine-rich splicing factor 4 [Myotis lucifugus] 18632 1751.86 15.41 16.79333333 0.124021759 Up 0.267366204 Pex11b peroxisomal biogenesis factor 11 beta K13352|1|1e-96|347|mmu:18632|peroxin-11B GO:0031231//intrinsic component of peroxisomal membrane;GO:0032991//macromolecular complex;GO:0031231//intrinsic component of peroxisomal membrane;GO:0032991//macromolecular complex;GO:0031231//intrinsic component of peroxisomal membrane;GO:0032991//macromolecular complex;GO:0031231//intrinsic component of peroxisomal membrane;GO:0032991//macromolecular complex;GO:0031231//intrinsic component of peroxisomal membrane;GO:0032991//macromolecular complex GO:0042802//identical protein binding;GO:0042802//identical protein binding;GO:0042802//identical protein binding;GO:0042802//identical protein binding;GO:0042802//identical protein binding GO:0051259//protein oligomerization;GO:0007031//peroxisome organization;GO:0032535//regulation of cellular component size;GO:0051259//protein oligomerization;GO:0007031//peroxisome organization;GO:0032535//regulation of cellular component size;GO:0051259//protein oligomerization;GO:0007031//peroxisome organization;GO:0032535//regulation of cellular component size;GO:0051259//protein oligomerization;GO:0007031//peroxisome organization;GO:0032535//regulation of cellular component size;GO:0051259//protein oligomerization;GO:0007031//peroxisome organization;GO:0032535//regulation of cellular component size gi|880956397|ref|XP_012979216.1|/3.56201e-133/PREDICTED: peroxisomal membrane protein 11B isoform X1 [Mesocricetus auratus] 226412 4812 17.94 16.55666667 -0.115767644 Down 0.267366204 R3hdm1 R3H domain containing 1 K02360|1|1e-41|175|nvi:100123797|a component of the cytoplasm (encore);K05054|3|7e-27|126|ocu:100338748|melanin-concentrating hormone receptor 2 - - - gi|50845430|ref|NP_861415.2|/0/R3H domain-containing protein 1 [Mus musculus] 28081 2635 16.25666667 17.63333333 0.11727375 Up 0.267366204 Fam104a "family with sequence similarity 104, member A" K20288|1|6e-19|99.0|mmu:16834|conserved oligomeric Golgi complex subunit 1 - - - gi|149588667|ref|NP_613064.2|/4.16522e-42/protein FAM104A [Mus musculus] 23853 2294 1.953333333 2.353333333 0.268767519 Up 0.267319192 Def6 differentially expressed in FDCP 6 K20072|1|5e-103|378|lcm:102366659|switch-associated protein 70 GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle GO:0008289//lipid binding - gi|81898580|sp|Q8C2K1.1|DEFI6_MOUSE/0/RecName: Full=Differentially expressed in FDCP 6; Short=DEF-6; AltName: Full=IRF4-binding protein; AltName: Full=SWAP-70-like adapter of T-cells 58180 6360 2.306666667 1.91 -0.272236899 Down 0.267319192 Hic2 hypermethylated in cancer 2 "K08583|1|2e-38|165|chx:102175325|calpain, small subunit 1;K09228|2|1e-34|152|gja:107122447|KRAB domain-containing zinc finger protein" GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding "GO:0006351//transcription, DNA-templated" gi|37360196|dbj|BAC98076.1|/0/mKIAA1020 protein [Mus musculus] 73122 5565 7.003333333 6.286666667 -0.155746486 Down 0.26730979 Tgfbrap1 "transforming growth factor, beta receptor associated protein 1" K20177|1|0.0|1721|mmu:73122|vacuolar protein sorting-associated protein 3 GO:0044424 GO:0005126//cytokine receptor binding "GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0015031//protein transport" gi|755492804|ref|XP_011236905.1|/0/PREDICTED: transforming growth factor-beta receptor-associated protein 1 isoform X3 [Mus musculus] 28113 1754 6.14 6.856666667 0.159268732 Up 0.26730979 Tinf2 Terf1 (TRF1)-interacting nuclear factor 2 K11112|1|0.0|848|mmu:28113|TERF1-interacting nuclear factor 2 - - - - 257632 4621 0.7 0.983333333 0.490325627 Up 0.267300387 Nod2 nucleotide-binding oligomerization domain containing 2 K10165|1|0.0|1827|mmu:257632|nucleotide-binding oligomerization domain-containing protein 2 GO:0016020//membrane;GO:0043226//organelle;GO:0044444//cytoplasmic part GO:0019900//kinase binding;GO:0042277//peptide binding;GO:0019904//protein domain specific binding;GO:0004520//endodeoxyribonuclease activity;GO:0005539//glycosaminoglycan binding;GO:0032550 GO:0002815;GO:0006461//protein complex assembly;GO:0032602//chemokine production;GO:0016567//protein ubiquitination;GO:0007254//JNK cascade;GO:0032494//response to peptidoglycan;GO:0000187//activation of MAPK activity;GO:0052166;GO:0007219//Notch signaling pathway;GO:0002828//regulation of type 2 immune response;GO:0032731//positive regulation of interleukin-1 beta production;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0008284//positive regulation of cell proliferation;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0002371//dendritic cell cytokine production;GO:0043331//response to dsRNA;GO:0002437//inflammatory response to antigenic stimulus;GO:0001818//negative regulation of cytokine production;GO:0042113//B cell activation;GO:0009581;GO:2000107//negative regulation of leukocyte apoptotic process;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0010912;GO:0002385//mucosal immune response;GO:0001774//microglial cell activation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0051353//positive regulation of oxidoreductase activity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032495//response to muramyl dipeptide;GO:0002688//regulation of leukocyte chemotaxis;GO:0044126;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032872//regulation of stress-activated MAPK cascade;GO:0002377//immunoglobulin production;GO:0006909//phagocytosis;GO:0002468//dendritic cell antigen processing and presentation;GO:0002456//T cell mediated immunity;GO:0002455//humoral immune response mediated by circulating immunoglobulin gi|29427819|sp|Q8K3Z0.1|NOD2_MOUSE/0/RecName: Full=Nucleotide-binding oligomerization domain-containing protein 2; AltName: Full=Caspase recruitment domain-containing protein 15 70591 4536 5.183333333 5.833333333 0.170440342 Up 0.267281583 5730455P16Rik RIKEN cDNA 5730455P16 gene - - - - gi|110625765|ref|NP_081748.1|/0/protein Njmu-R1 [Mus musculus] 72981 3478 28.27333333 26.25333333 -0.106941372 Down 0.267281583 Prkrir "protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)" K14829|1|1e-11|75.1|hmg:100196989|pre-rRNA-processing protein IPI3;K10134|2|5e-11|73.2|api:100159951|etoposide-induced 2.4 mRNA;K04279|4|3e-07|60.8|lcm:102358682|platelet-activating factor receptor GO:0043231//intracellular membrane-bounded organelle "GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0050896//response to stimulus;GO:0008283//cell proliferation;GO:0006796//phosphate-containing compound metabolic process;GO:0007154//cell communication gi|33469019|ref|NP_082686.1|/0/52 kDa repressor of the inhibitor of the protein kinase [Mus musculus] 68916 2626.34 5.116666667 5.77 0.173367069 Up 0.267281583 Cdkal1 CDK5 regulatory subunit associated protein 1-like 1 K15865|1|0.0|1021|mmu:68916|threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5] - - - - 108679 1843 56.75666667 60.88 0.101178497 Up 0.267187559 Cops8 COP9 signalosome subunit 8 K12181|1|9e-115|416|mmu:108679|COP9 signalosome complex subunit 8 - - - - 18729 2043 0.296666667 0.113333333 -1.38827059 Down 0.267168754 Pira6 paired-Ig-like receptor A6 K06512|1|0.0|1274|mmu:18729|leukocyte immunoglobulin-like receptor - - GO:0002573//myeloid leukocyte differentiation;GO:0001773//myeloid dendritic cell activation;GO:0007166//cell surface receptor signaling pathway;GO:0002449 gi|574997035|ref|NP_001276357.1|/0/paired-Ig-like receptor A6 isoform c precursor [Mus musculus] 66291 927 28.31 26.30333333 -0.10606611 Down 0.267149949 Smim8 small integral membrane protein 8 "K05673|1|1e-18|96.3|bfo:BRAFLDRAFT_86619|ATP-binding cassette, subfamily C (CFTR/MRP), member 4" GO:0031224//intrinsic component of membrane - - gi|13384890|ref|NP_079747.1|/3.72705e-50/small integral membrane protein 8 [Mus musculus] 320977 5195 0.943333333 1.25 0.406088543 Up 0.267093535 A330023F24Rik RIKEN cDNA A330023F24 gene - - - - - 67370 4492.19 1.25 0.94 -0.411195433 Down 0.267093535 Zfp606 zinc finger protein 606 K09228|1|3e-21|106|ngi:103725461|KRAB domain-containing zinc finger protein GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|890782321|ref|NP_001297549.1|/0/zinc finger protein 606 isoform 3 [Mus musculus] 226747 8831 2.243333333 1.85 -0.278118733 Down 0.267027718 Ahctf1 AT hook containing transcription factor 1 - "GO:0034399//nuclear periphery;GO:0000775//chromosome, centromeric region;GO:0005635//nuclear envelope" GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0050658//RNA transport;GO:0048534//hematopoietic or lymphoid organ development;GO:0006999//nuclear pore organization;GO:0045184//establishment of protein localization;GO:0000087//mitotic M phase" "gi|148681217|gb|EDL13164.1|/0/AT hook containing transcription factor 1, isoform CRA_b, partial [Mus musculus]" 212547 2866 2.19 1.803333333 -0.280264776 Down 0.267027718 Nepro nucleolus and neural progenitor protein - - - - - 19383 1584.92 54.83333333 58.86666667 0.102397759 Up 0.266952499 Raly hnRNP-associated with lethal yellow K12895|1|6e-108|394|rno:296301|heterogeneous nuclear ribonucleoprotein C-like 2 - - - - 226823 3703 4.116666667 3.586666667 -0.198832964 Down 0.266943097 Kctd3 potassium channel tetramerisation domain containing 3 "K06115|1|4e-91|339|asn:102373253|spectrin beta;K03849|2|2e-10|71.2|cmk:103177229|alpha-1,3-glucosyltransferase [EC:2.4.1.265];K20131|3|5e-09|66.6|pale:102883240|Rab5 GDP/GTP exchange factor" - - GO:0051259//protein oligomerization "gi|148681085|gb|EDL13032.1|/0/potassium channel tetramerisation domain containing 3, isoform CRA_b, partial [Mus musculus]" 56055 2982 24.35333333 26.34 0.113136093 Up 0.26691489 Gtpbp2 GTP binding protein 2 K14416|1|8e-18|95.5|nvi:100116941|elongation factor 1 alpha-like protein - GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 - gi|225543388|ref|NP_062527.2|/0/GTP-binding protein 2 isoform 1 [Mus musculus] 57782 3380 2.076666667 1.696666667 -0.291566507 Down 0.266858475 Rbak RB-associated KRAB zinc finger K09228|1|0.0|1530|mmu:57782|KRAB domain-containing zinc finger protein - - - - 73102 6251 2.106666667 1.726666667 -0.28697246 Down 0.266858475 Slc22a23 "solute carrier family 22, member 23" "K08215|1|0.0|1262|mmu:73102|MFS transporter, OCT family, solute carrier family 22 (organic anion transporter), member 23" GO:0031224//intrinsic component of membrane GO:0005215//transporter activity GO:0044765//single-organism transport;GO:0044763 gi|85701678|ref|NP_001028339.1|/0/solute carrier family 22 member 23 [Mus musculus] 76624 677 0.213333333 0.423333333 0.988684687 Up 0.266830268 1700099I09Rik RIKEN cDNA 1700099I09 gene K08789|1|7e-17|89.4|pale:102878651|microtubule-associated serine/threonine kinase [EC:2.7.11.1] - - - - 69190 2471 58.22666667 62.20666667 0.095389171 Up 0.266820866 Dym dymeclin - GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0005515//protein binding GO:0001501//skeletal system development;GO:0006996//organelle organization "gi|148677553|gb|EDL09500.1|/0/dymeclin, isoform CRA_f, partial [Mus musculus]" 217201 3230 7.28 8.066666667 0.148034191 Up 0.266792659 Rundc1 RUN domain containing 1 K20177|1|3e-68|263|loa:LOAG_00231|vacuolar protein sorting-associated protein 3;K20176|2|1e-09|68.6|api:100163032|small G protein signaling modulator 3 - - - gi|262263316|ref|NP_766154.2|/0/RUN domain-containing protein 1 [Mus musculus] 54637 1206 7.333333333 8.12 0.147010609 Up 0.266792659 Praf2 PRA1 domain family 2 K20392|1|3e-64|248|mmu:54637|PRA1 family protein 2 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0045184//establishment of protein localization gi|20070422|ref|NP_613068.1|/2.63071e-63/PRA1 family protein 2 [Mus musculus] 67154 3680 12.34333333 11.27333333 -0.13081789 Down 0.266792659 Mtdh metadherin K01265|1|2e-31|140|cmk:103188901|methionyl aminopeptidase [EC:3.4.11.18] GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0044459;GO:0044451;GO:0044444//cytoplasmic part GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding GO:0001525//angiogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006914//autophagy "gi|149066555|gb|EDM16428.1|/0/metadherin, isoform CRA_a [Rattus norvegicus]" 13992 1954 24.98333333 26.96333333 0.110032883 Up 0.266755049 Khdrbs3 "KH domain containing, RNA binding, signal transduction associated 3" "K14942|1|2e-163|578|mmu:13992|KH domain-containing, RNA-binding, signal transduction-associated protein 3" GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0019904//protein domain specific binding "GO:0008380//RNA splicing;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated" "gi|117647236|ref|NP_034288.2|/1.63418e-162/KH domain-containing, RNA-binding, signal transduction-associated protein 3 [Mus musculus]" 17872 2345 26.06 28.04333333 0.10582076 Up 0.266755049 Ppp1r15a "protein phosphatase 1, regulatory (inhibitor) subunit 15A" K14019|1|0.0|1104|mmu:17872|protein phosphatase 1 regulatory subunit 15A - - GO:0006984//ER-nucleus signaling pathway;GO:0012501//programmed cell death;GO:0006412//translation gi|6678978|ref|NP_032680.1|/0/protein phosphatase 1 regulatory subunit 15A [Mus musculus] 102632492 1200 0.163333333 0.356666667 1.126757142 Up 0.266736244 Gm30551 "predicted gene, 30551" K04574|1|2e-11|57.4|mmu:380684|neurofilament heavy polypeptide - - - - 57765 2552 0.026666667 0.166666667 2.64385619 Up 0.266689232 Tbx21 T-box 21 K10166|1|0.0|1031|mmu:57765|T-box protein 21 GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding "GO:0006351//transcription, DNA-templated;GO:0045830//positive regulation of isotype switching;GO:0051707//response to other organism;GO:0050900//leukocyte migration;GO:0030098//lymphocyte differentiation" gi|247269497|ref|NP_062380.2|/0/T-box transcription factor TBX21 [Mus musculus] 16326 2135 0.026666667 0.166666667 2.64385619 Up 0.266689232 Inhbe inhibin beta-E "K04667|1|0.0|655|mmu:16326|inhibin, beta" - - - - 56433 991 26.69333333 24.72333333 -0.110606205 Down 0.266623416 Vps29 VPS29 retromer complex component K18467|1|5e-102|373|oaa:100073979|vacuolar protein sorting-associated protein 29 GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0016791//phosphatase activity GO:0006892//post-Golgi vesicle-mediated transport;GO:0045184//establishment of protein localization "gi|71042152|pdb|1Z2W|A/2.11449e-102/Chain A, Crystal Structure Of Mouse Vps29 Complexed With Mn2+" 407819 1082 27.96666667 26 -0.105196687 Down 0.266623416 BC031181 cDNA sequence BC031181 - - - GO:0007249//I-kappaB kinase/NF-kappaB signaling "gi|148677555|gb|EDL09502.1|/2.30484e-60/cDNA sequence BC031181, isoform CRA_a, partial [Mus musculus]" 66566 1252.14 8.8 9.696666667 0.139985367 Up 0.266623416 Ntpcr "nucleoside-triphosphatase, cancer-related" K06928|1|9e-101|369|mmu:66566|nucleoside-triphosphatase [EC:3.6.1.15] - GO:0016791//phosphatase activity;GO:0016462//pyrophosphatase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process gi|893557664|ref|NP_001297617.1|/3.71616e-63/cancer-related nucleoside-triphosphatase homolog isoform 2 [Mus musculus] 231093 3273.95 15.02 16.37333333 0.124463247 Up 0.266585806 Agbl5 ATP/GTP binding protein-like 5 K05840|1|1e-08|65.1|myb:102243447|dopamine receptor D5;K04257|2|1e-08|64.7|shr:100920260|olfactory receptor GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding GO:0035608//protein deglutamylation;GO:0035608//protein deglutamylation;GO:0035608//protein deglutamylation;GO:0035608//protein deglutamylation gi|568934055|ref|XP_006503936.1|/0/PREDICTED: cytosolic carboxypeptidase-like protein 5 isoform X6 [Mus musculus] 236539 1871 1.286666667 0.973333333 -0.402632478 Down 0.266510587 Phgdh 3-phosphoglycerate dehydrogenase K00058|1|0.0|1032|mmu:236539|D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95] GO:0044444//cytoplasmic part "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding" GO:0007417//central nervous system development;GO:0007049//cell cycle;GO:0030030//cell projection organization;GO:0006790//sulfur compound metabolic process;GO:0009064//glutamine family amino acid metabolic process;GO:0010001//glial cell differentiation;GO:0008652//cellular amino acid biosynthetic process;GO:0006563//L-serine metabolic process;GO:0010467//gene expression;GO:0009066 gi|52353955|ref|NP_058662.2|/0/D-3-phosphoglycerate dehydrogenase [Mus musculus] 18143 4180 0.983333333 1.293333333 0.395341698 Up 0.266510587 Npas2 neuronal PAS domain protein 2 K09026|1|0.0|1408|mmu:18143|neuronal PAS domain-containing protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0031072//heat shock protein binding;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity GO:0007626//locomotory behavior;GO:0007154//cell communication;GO:0006366//transcription from RNA polymerase II promoter;GO:0048512//circadian behavior gi|161621277|ref|NP_032745.2|/0/neuronal PAS domain-containing protein 2 [Mus musculus] 11622 5494 1.196666667 0.893333333 -0.421750843 Down 0.266491782 Ahr aryl-hydrocarbon receptor K09093|1|0.0|1295|mmu:11622|aryl hydrocarbon receptor GO:0031981//nuclear lumen;GO:0034751//aryl hydrocarbon receptor complex;GO:0044444//cytoplasmic part "GO:0038023//signaling receptor activity;GO:0000975//regulatory region DNA binding;GO:0046983//protein dimerization activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0031072//heat shock protein binding" GO:0040009//regulation of growth rate;GO:0030098//lymphocyte differentiation;GO:0019229//regulation of vasoconstriction;GO:0003214//cardiac left ventricle morphogenesis;GO:0045898//regulation of RNA polymerase II transcriptional preinitiation complex assembly;GO:0032989;GO:0051384//response to glucocorticoid;GO:0009791//post-embryonic development;GO:0001822//kidney development;GO:0042100//B cell proliferation;GO:0001654//eye development;GO:0001782//B cell homeostasis;GO:0007165//signal transduction;GO:0048771//tissue remodeling;GO:0060537//muscle tissue development;GO:0070265//necrotic cell death;GO:0003073//regulation of systemic arterial blood pressure;GO:0008361//regulation of cell size;GO:0043627//response to estrogen;GO:0051591//response to cAMP;GO:0008585//female gonad development;GO:0046620//regulation of organ growth;GO:0001525//angiogenesis;GO:0012501//programmed cell death "gi|148704916|gb|EDL36863.1|/0/aryl-hydrocarbon receptor, partial [Mus musculus]" 20658 8336 25.11333333 27.07 0.108241355 Up 0.266463575 Son Son DNA binding protein K06792|1|1e-28|132|cmk:103188388|aggrecan 1 - - - "gi|148671870|gb|EDL03817.1|/0/Son cell proliferation protein, isoform CRA_a [Mus musculus]" 17769 5633.61 4.49 3.926666667 -0.193410312 Down 0.266463575 Mthfr "5,10-methylenetetrahydrofolate reductase" K00297|1|0.0|1261|mmu:17769|methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20] GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0042995//cell projection;GO:0044444//cytoplasmic part "GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0016597//amino acid binding;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0016597//amino acid binding;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0016597//amino acid binding" GO:0000097//sulfur amino acid biosynthetic process;GO:0001101//response to acid chemical;GO:0010243//response to organonitrogen compound;GO:0006730//one-carbon metabolic process;GO:0014070//response to organic cyclic compound;GO:0034097//response to cytokine;GO:0006760//folic acid-containing compound metabolic process;GO:0000097//sulfur amino acid biosynthetic process;GO:0001101//response to acid chemical;GO:0010243//response to organonitrogen compound;GO:0006730//one-carbon metabolic process;GO:0014070//response to organic cyclic compound;GO:0034097//response to cytokine;GO:0006760//folic acid-containing compound metabolic process;GO:0000097//sulfur amino acid biosynthetic process;GO:0001101//response to acid chemical;GO:0010243//response to organonitrogen compound;GO:0006730//one-carbon metabolic process;GO:0014070//response to organic cyclic compound;GO:0034097//response to cytokine;GO:0006760//folic acid-containing compound metabolic process gi|239985494|ref|NP_001155270.1|/0/methylenetetrahydrofolate reductase isoform a [Mus musculus] 407803 843 0.786666667 1.073333333 0.448273829 Up 0.266425966 BC051226 cDNA sequence BC051226 - - - - - 68121 2608 1.1 0.806666667 -0.447458977 Down 0.266425966 Cep70 centrosomal protein 70 K16802|1|0.0|1102|mmu:68121|centrosomal protein CEP70 GO:0005815//microtubule organizing center;GO:0005635//nuclear envelope;GO:0031981//nuclear lumen - - gi|117606316|ref|NP_076362.2|/0/centrosomal protein of 70 kDa [Mus musculus] 117599 4540 3.74 3.236666667 -0.208529475 Down 0.266378954 Helb helicase (DNA) B K15254|1|0.0|2117|mmu:117599|DNA helicase B [EC:3.6.4.12] GO:0043234//protein complex GO:0032550;GO:0004003//ATP-dependent DNA helicase activity GO:0009154//purine ribonucleotide catabolic process;GO:0006260//DNA replication gi|47847400|dbj|BAD21372.1|/0/mFLJ00057 protein [Mus musculus] 268469 2668 3.623333333 3.126666667 -0.212692113 Down 0.266378954 Zfp652 zinc finger protein 652 K10518|1|4e-148|528|cjo:107308845|zinc finger and BTB domain-containing protein 47 GO:0005622//intracellular GO:0046872//metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|148684045|gb|EDL15992.1|/0/mCG3800 [Mus musculus] 216860 5221.46 16.23333333 14.89 -0.124615518 Down 0.266294332 Neurl4 neuralized E3 ubiquitin protein ligase 4 K16777|1|0.0|2654|mmu:216860|neuralized-like protein 4 GO:0043232;GO:0043232;GO:0043232 - - gi|597955310|ref|NP_001278047.1|/0/neuralized-like protein 4 isoform 2 [Mus musculus] 226591 4395 5.866666667 6.573333333 0.164084123 Up 0.26628493 Tiprl "TIP41, TOR signalling pathway regulator-like (S. cerevisiae)" K17607|1|6e-140|501|mmu:226591|type 2A phosphatase activator TIP41 GO:0044424 - GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0006974//cellular response to DNA damage stimulus gi|21704010|ref|NP_663488.1|/4.99565e-139/TIP41-like protein [Mus musculus] 80860 2162 6.213333333 6.92 0.155404584 Up 0.26628493 Ghdc GH3 domain containing K11224|1|2e-39|167|cmy:102941843|signal transducer and activator of transcription 5B - - - gi|13994199|ref|NP_114077.1|/0/GH3 domain-containing protein precursor [Mus musculus] 60594 2828 6.236666667 6.95 0.156237825 Up 0.26628493 Capn12 calpain 12 K04740|1|0.0|1359|mmu:60594|calpain-12 [EC:3.4.22.-] GO:0044464 "GO:0046872//metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process gi|160948579|ref|NP_001104277.1|/0/calpain-12 [Mus musculus] 54524 1857 1.646666667 1.303333333 -0.337342434 Down 0.266228516 Syt6 synaptotagmin VI K19906|1|0.0|947|mmu:54524|synaptotagmin-6 GO:0031224//intrinsic component of membrane;GO:0044432;GO:0008021//synaptic vesicle;GO:0031224//intrinsic component of membrane;GO:0044432;GO:0008021//synaptic vesicle;GO:0031224//intrinsic component of membrane;GO:0044432;GO:0008021//synaptic vesicle;GO:0031224//intrinsic component of membrane;GO:0044432;GO:0008021//synaptic vesicle;GO:0031224//intrinsic component of membrane;GO:0044432;GO:0008021//synaptic vesicle GO:0043169//cation binding;GO:0000149//SNARE binding;GO:0005543//phospholipid binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0000149//SNARE binding;GO:0005543//phospholipid binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0000149//SNARE binding;GO:0005543//phospholipid binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0000149//SNARE binding;GO:0005543//phospholipid binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0000149//SNARE binding;GO:0005543//phospholipid binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity GO:0007340//acrosome reaction;GO:0007340//acrosome reaction;GO:0007340//acrosome reaction;GO:0007340//acrosome reaction;GO:0007340//acrosome reaction gi|568923259|ref|XP_006501767.1|/0/PREDICTED: synaptotagmin-6 isoform X2 [Mus musculus] 58223 3317.05 2.926666667 3.4 0.216276307 Up 0.266153296 Mmp19 matrix metallopeptidase 19 K07998|1|0.0|1075|mmu:58223|matrix metalloproteinase-19 (RASI) [EC:3.4.24.-] GO:0031224//intrinsic component of membrane;GO:0031012//extracellular matrix;GO:0031224//intrinsic component of membrane;GO:0031012//extracellular matrix GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0048869//cellular developmental process;GO:0046683//response to organophosphorus;GO:0009719;GO:0008585//female gonad development;GO:0019538//protein metabolic process;GO:0032963//collagen metabolic process;GO:0048869//cellular developmental process;GO:0046683//response to organophosphorus;GO:0009719;GO:0008585//female gonad development;GO:0019538//protein metabolic process;GO:0032963//collagen metabolic process gi|10946772|ref|NP_067387.1|/0/matrix metalloproteinase-19 isoform 1 preproprotein [Mus musculus] 73951 1402 2.883333333 3.356666667 0.219291645 Up 0.266153296 4930413G21Rik RIKEN cDNA 4930413G21 gene - - - - - 66313 5346 8.03 7.246666667 -0.148082453 Down 0.26604987 Smurf2 SMAD specific E3 ubiquitin protein ligase 2 K04678|1|0.0|1536|mmu:66313|E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26] - - - gi|254939680|ref|NP_079757.2|/0/E3 ubiquitin-protein ligase SMURF2 [Mus musculus] 170789 1161 7.67 6.89 -0.154722595 Down 0.26604987 Acot8 acyl-CoA thioesterase 8 K11992|1|0.0|661|rno:170588|acyl-CoA thioesterase 8 [EC:3.1.2.27] GO:0044439 GO:0005515//protein binding;GO:0047617//acyl-CoA hydrolase activity GO:0006732;GO:0043648//dicarboxylic acid metabolic process;GO:0007031//peroxisome organization gi|254587964|ref|NP_573503.2|/0/acyl-coenzyme A thioesterase 8 [Mus musculus] 66873 5377 2.606666667 2.186666667 -0.253472793 Down 0.265955846 Tril TLR4 interactor with leucine-rich repeats K13023|1|1e-36|158|cjc:100385520|carboxypeptidase N regulatory subunit GO:0016021//integral component of membrane GO:0008289//lipid binding GO:0002224//toll-like receptor signaling pathway;GO:0001817//regulation of cytokine production gi|21313256|ref|NP_080093.1|/0/TLR4 interactor with leucine rich repeats precursor [Mus musculus] 30951 1413 2.243333333 2.66 0.245782242 Up 0.265955846 Cbx8 chromobox 8 K11455|1|1e-166|588|mmu:30951|chromobox protein 8 GO:0031519//PcG protein complex;GO:0031981//nuclear lumen;GO:0000785//chromatin GO:0003723//RNA binding;GO:0042393//histone binding;GO:0019787//ubiquitin-like protein transferase activity GO:0016458//gene silencing;GO:0016567//protein ubiquitination;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter gi|7304947|ref|NP_038954.1|/1.0328e-165/chromobox protein homolog 8 [Mus musculus] 75210 1944.48 2.233333333 2.653333333 0.248607335 Up 0.265955846 Prr3 proline-rich polypeptide 3 - - GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding - gi|530537269|ref|NP_001268954.1|/5.41144e-25/proline-rich protein 3 isoform d [Mus musculus] 237107 4877 9.796666667 8.903333333 -0.137945383 Down 0.265955846 Gnl3l guanine nucleotide binding protein-like 3 (nucleolar)-like K14538|1|0.0|1020|mmu:237107|nuclear GTP-binding protein - - - "gi|148675551|gb|EDL07498.1|/0/guanine nucleotide binding protein-like 3 (nucleolar)-like, partial [Mus musculus]" 226154 2782.22 50.49333333 54.27666667 0.104239202 Up 0.265937042 Lzts2 "leucine zipper, putative tumor suppressor 2" - GO:0005856//cytoskeleton;GO:0005856//cytoskeleton;GO:0005856//cytoskeleton - GO:0007049//cell cycle;GO:0050794//regulation of cellular process;GO:0008219//cell death;GO:0007049//cell cycle;GO:0050794//regulation of cellular process;GO:0008219//cell death;GO:0007049//cell cycle;GO:0050794//regulation of cellular process;GO:0008219//cell death gi|37360556|dbj|BAC98256.1|/8.41328e-126/mKIAA1813 protein [Mus musculus] 67027 2241 24.84333333 26.77 0.10775838 Up 0.265927639 Mkrn2 "makorin, ring finger protein, 2" K15687|1|0.0|810|mmu:67027|E3 ubiquitin-protein ligase makorin [EC:2.3.2.27] GO:0044464 GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0097159//organic cyclic compound binding GO:0032446//protein modification by small protein conjugation gi|88853570|ref|NP_075779.2|/0/probable E3 ubiquitin-protein ligase makorin-2 [Mus musculus] 52014 4614 12.42666667 11.37333333 -0.127784213 Down 0.265908834 Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit K19177|1|5e-133|478|mmu:52014|dehydrodolichyl diphosphate syntase complex subunit NUS1 [EC:2.5.1.87] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0016740//transferase activity GO:0030301//cholesterol transport;GO:0055088//lipid homeostasis;GO:0048869//cellular developmental process gi|13384840|ref|NP_084526.1|/4.76815e-132/dehydrodolichyl diphosphate syntase complex subunit Nus1 [Mus musculus] 78266 4632 5.79 5.15 -0.168990916 Down 0.265899432 Zfp687 zinc finger protein 687 K19325|1|2e-136|490|pss:102456480|zinc finger protein 592 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|27229259|ref|NP_084350.1|/0/zinc finger protein 687 [Mus musculus] 434784 1397 0.35 0.163333333 -1.099535674 Down 0.26585242 Ldoc1 "leucine zipper, down-regulated in cancer 1" - GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0008283//cell proliferation gi|66348058|ref|NP_001018097.1|/6.55919e-56/protein LDOC1 [Mus musculus] 75767 6402 0.166666667 0.356666667 1.097610797 Up 0.26585242 Rab11fip1 RAB11 family interacting protein 1 (class I) K12484|1|0.0|986|mmu:75767|Rab11 family-interacting protein 1/2/5 GO:0005768//endosome;GO:0016020//membrane;GO:0031410//cytoplasmic vesicle - GO:0045184//establishment of protein localization gi|124249097|ref|NP_001074282.1|/0/rab11 family-interacting protein 1 isoform 1 [Mus musculus] 68251 1592 50.91666667 54.64666667 0.101995523 Up 0.265786603 Babam1 BRISC and BRCA1 A complex member 1 K11406|1|2e-153|544|chx:102175200|histone deacetylase 4/5 [EC:3.5.1.98];K11844|2|1e-06|57.4|phu:Phum_PHUM024700|ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12] - - - - 100041286 592 1.406666667 1.76 0.323294931 Up 0.265720787 Snhg15 small nucleolar RNA host gene 15 K09228|1|6e-06|52.8|rno:680258|KRAB domain-containing zinc finger protein - - - "gi|148708652|gb|EDL40599.1|/4.41244e-28/mCG21386, isoform CRA_a [Mus musculus]" 73835 734 0.416666667 0.66 0.663572335 Up 0.26565497 Ifitm5 interferon induced transmembrane protein 5 K06566|1|1e-62|241|mmu:73835|interferon induced transmembrane protein GO:0031224//intrinsic component of membrane - GO:0030278//regulation of ossification;GO:0050896//response to stimulus;GO:0032502//developmental process gi|33504579|ref|NP_444318.1|/1.03199e-61/interferon-induced transmembrane protein 5 [Mus musculus] 243961 7596 0.743333333 0.496666667 -0.581731379 Down 0.265626763 Shank1 SH3/ankyrin domain gene 1 K15009|1|0.0|2565|mmu:243961|SH3 and multiple ankyrin repeat domains protein GO:0008328//ionotropic glutamate receptor complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane GO:0030159//receptor signaling complex scaffold activity;GO:0019904//protein domain specific binding;GO:0071855//neuropeptide receptor binding;GO:0035254//glutamate receptor binding GO:0051094//positive regulation of developmental process;GO:0051705;GO:0007613//memory;GO:0048812//neuron projection morphogenesis;GO:0051017//actin filament bundle assembly;GO:0045838//positive regulation of membrane potential;GO:0007635//chemosensory behavior;GO:0044704//single-organism reproductive behavior;GO:0060004//reflex;GO:0046958//nonassociative learning;GO:0008104//protein localization;GO:0065003;GO:0010469//regulation of receptor activity;GO:0050905//neuromuscular process gi|283549150|ref|NP_001029287.1|/0/SH3 and multiple ankyrin repeat domains protein 1 [Mus musculus] 100038993 2680 0.996666667 0.713333333 -0.482534688 Down 0.265589153 Gm2002 predicted gene 2002 K05056|1|0.0|795|mmu:100038993|interleukin 11 receptor alpha GO:0031224//intrinsic component of membrane GO:0004896//cytokine receptor activity;GO:0046983//protein dimerization activity;GO:0019838//growth factor binding GO:0001893//maternal placenta development;GO:0019221//cytokine-mediated signaling pathway;GO:0008283//cell proliferation "gi|755505907|ref|XP_006537576.2|/0/PREDICTED: interleukin 11 receptor, alpha chain 2-like isoform X3 [Mus musculus]" 56068 3109 0.996666667 0.716666667 -0.475808825 Down 0.265589153 Ammecr1 "Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1" - - - - "gi|148682791|gb|EDL14738.1|/8.1029e-125/Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 homolog (human), partial [Mus musculus]" 16158 2680 0.996666667 0.713333333 -0.482534688 Down 0.265589153 Il11ra2 "interleukin 11 receptor, alpha chain 2" K05056|1|0.0|795|mmu:100038993|interleukin 11 receptor alpha GO:0031224//intrinsic component of membrane GO:0004896//cytokine receptor activity;GO:0046983//protein dimerization activity;GO:0019838//growth factor binding GO:0001893//maternal placenta development;GO:0019221//cytokine-mediated signaling pathway;GO:0008283//cell proliferation "gi|755505907|ref|XP_006537576.2|/0/PREDICTED: interleukin 11 receptor, alpha chain 2-like isoform X3 [Mus musculus]" 224807 3237 53.09 56.75333333 0.096264988 Up 0.265579751 Tmem63b transmembrane protein 63b K10165|1|8e-62|241|cjc:100414962|nucleotide-binding oligomerization domain-containing protein 2 GO:0031224//intrinsic component of membrane - - "gi|119624652|gb|EAX04247.1|/0/transmembrane protein 63B, isoform CRA_b [Homo sapiens]" 258216 1023 0.443333333 0.233333333 -0.925999419 Down 0.265551544 Olfr1034 olfactory receptor 1034 K04257|1|4e-143|509|mmu:258216|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|289629190|ref|NP_001011872.2|/2.87497e-142/olfactory receptor 1034 [Mus musculus] 12462 1957 50.17 53.80666667 0.100959996 Up 0.265532739 Cct3 "chaperonin containing Tcp1, subunit 3 (gamma)" K09495|1|0.0|1067|mmu:12462|T-complex protein 1 subunit gamma GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane GO:0032550;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0035036//sperm-egg recognition gi|6753320|ref|NP_033966.1|/0/T-complex protein 1 subunit gamma [Mus musculus] 66972 3376 26.54666667 24.65 -0.106943074 Down 0.265485727 Slc25a23 "solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23" "K14684|1|0.0|913|mmu:66972|solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0051234//establishment of localization;GO:0044763 "gi|148706281|gb|EDL38228.1|/0/solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23, isoform CRA_b, partial [Mus musculus]" 66958 2141.49 56.62666667 52.99333333 -0.095670731 Down 0.265448118 Tmx2 thioredoxin-related transmembrane protein 2 K20030|1|3e-74|282|apla:101799873|palmitoyltransferase ZDHHC5/8 [EC:2.3.1.225] GO:0031224//intrinsic component of membrane - GO:0019725//cellular homeostasis;GO:0019725//cellular homeostasis gi|595582387|ref|NP_001277680.1|/1.80027e-140/thioredoxin-related transmembrane protein 2 isoform b [Mus musculus] 320655 2424 6.8 7.57 0.154758554 Up 0.265391703 Pgap3 post-GPI attachment to proteins 3 - GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane GO:0016787//hydrolase activity GO:0006664//glycolipid metabolic process;GO:0006497//protein lipidation gi|114326508|ref|NP_001028709.2|/5.60019e-163/post-GPI attachment to proteins factor 3 precursor [Mus musculus] 68675 3899.68 1.883333333 1.52 -0.309217043 Down 0.265382301 Fam172a "family with sequence similarity 172, member A" - - - - gi|568983570|ref|XP_006517413.1|/0/PREDICTED: protein FAM172A isoform X1 [Mus musculus] 67959 1894.25 51.17333333 54.79 0.098520393 Up 0.265372899 Puf60 poly-U binding splicing factor 60 K12838|1|0.0|842|mmu:67959|poly(U)-binding-splicing factor PUF60 GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0012501//programmed cell death;GO:0006396//RNA processing;GO:0006351//transcription, DNA-templated;GO:0012501//programmed cell death;GO:0006396//RNA processing;GO:0006351//transcription, DNA-templated;GO:0012501//programmed cell death;GO:0006396//RNA processing;GO:0006351//transcription, DNA-templated" "gi|148697575|gb|EDL29522.1|/0/RIKEN cDNA 2410104I19, isoform CRA_c [Mus musculus]" 100415912 1075 0.513333333 0.293333333 -0.807354922 Down 0.265307082 Gm11665 predicted gene 11665 - - - - - 240174 7896 1.076666667 1.393333333 0.371968777 Up 0.265278875 Thada thyroid adenoma associated - - - - gi|241982820|ref|NP_898842.2|/0/thyroid adenoma-associated protein homolog [Mus musculus] 70508 8742 1.086666667 1.406666667 0.372371034 Up 0.265278875 Bbx bobby sox homolog (Drosophila) K20225|1|8e-24|117|xtr:100497168|capicua transcriptional repressor GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated;GO:0001501//skeletal system development" "gi|148665707|gb|EDK98123.1|/0/bobby sox homolog (Drosophila), isoform CRA_b, partial [Mus musculus]" 21389 1731 1.083333333 1.403333333 0.373380515 Up 0.265278875 Tbx6 T-box 6 K10180|1|0.0|791|mmu:21389|T-box protein 6 GO:0043231//intracellular membrane-bounded organelle "GO:0001085//RNA polymerase II transcription factor binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" GO:0045165//cell fate commitment;GO:0007165//signal transduction;GO:0010467//gene expression;GO:0001704//formation of primary germ layer gi|48928035|ref|NP_035668.2|/0/T-box transcription factor TBX6 [Mus musculus] 234358 2996 1.393333333 1.076666667 -0.371968777 Down 0.265278875 Zfp930 zinc finger protein 930 K09228|1|0.0|971|mmu:234358|KRAB domain-containing zinc finger protein - - - "gi|148696785|gb|EDL28732.1|/0/mCG140597, partial [Mus musculus]" 58202 2650 14.49 15.79 0.123953576 Up 0.265241265 Nelfb negative elongation factor complex member B K15180|1|0.0|1062|rno:311796|negative elongation factor B GO:0008023//transcription elongation factor complex;GO:0008023//transcription elongation factor complex - "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|38372348|sp|Q8C4Y3.2|NELFB_MOUSE/0/RecName: Full=Negative elongation factor B; Short=NELF-B; AltName: Full=Cofactor of BRCA1 69470 4401 15.78 14.48333333 -0.123703529 Down 0.265241265 Tmem127 transmembrane protein 127 - GO:0031224//intrinsic component of membrane;GO:0044424 - GO:0008283//cell proliferation;GO:0009968//negative regulation of signal transduction "gi|148696233|gb|EDL28180.1|/9.17054e-109/transmembrane protein 127, isoform CRA_a, partial [Mus musculus]" 233865 6191 2.433333333 2.036666667 -0.256724084 Down 0.265231863 D430042O09Rik RIKEN cDNA D430042O09 gene - - - - gi|124486628|ref|NP_001074491.1|/0/uncharacterized protein KIAA0556 [Mus musculus] 246730 1889 3.576666667 4.096666667 0.19583484 Up 0.265194253 Oas1a 2'-5' oligoadenylate synthetase 1A K14216|1|0.0|721|mmu:246730|2'-5'-oligoadenylate synthetase [EC:2.7.7.84] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0032550;GO:0070566//adenylyltransferase activity;GO:0003723//RNA binding GO:0006461//protein complex assembly;GO:0051707//response to other organism;GO:0019079//viral genome replication;GO:0032069;GO:0002252;GO:0035455//response to interferon-alpha;GO:0006163//purine nucleotide metabolic process;GO:0006952//defense response gi|568937204|ref|XP_006530393.1|/0/PREDICTED: 2'-5'-oligoadenylate synthase 1A isoform X1 [Mus musculus] 58916 2207 47.78 51.35666667 0.104144713 Up 0.265090827 Myot myotilin K19875|1|0.0|954|mmu:58916|myotilin GO:0016020//membrane;GO:0031674//I band GO:0042805//actinin binding - gi|84781791|ref|NP_001028793.1|/0/myotilin [Mus musculus] 20315 4296.36 54.73333333 51.15666667 -0.097497459 Down 0.265090827 Cxcl12 chemokine (C-X-C motif) ligand 12 K10031|1|3e-39|166|mmu:20315|C-X-C motif chemokine 12 GO:0009986//cell surface;GO:0016020//membrane;GO:0044421;GO:0009986//cell surface;GO:0016020//membrane;GO:0044421;GO:0009986//cell surface;GO:0016020//membrane;GO:0044421 GO:0042379//chemokine receptor binding;GO:0005125//cytokine activity;GO:0042379//chemokine receptor binding;GO:0005125//cytokine activity;GO:0042379//chemokine receptor binding;GO:0005125//cytokine activity GO:0014046;GO:0001935//endothelial cell proliferation;GO:0007411//axon guidance;GO:0003006//developmental process involved in reproduction;GO:0019221//cytokine-mediated signaling pathway;GO:0021537//telencephalon development;GO:0007626//locomotory behavior;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0007276//gamete generation;GO:0001525//angiogenesis;GO:0043066//negative regulation of apoptotic process;GO:0042110//T cell activation;GO:0006816//calcium ion transport;GO:0009887//organ morphogenesis;GO:0050927//positive regulation of positive chemotaxis;GO:0045773//positive regulation of axon extension;GO:0014046;GO:0001935//endothelial cell proliferation;GO:0009628//response to abiotic stimulus;GO:0007411//axon guidance;GO:0003006//developmental process involved in reproduction;GO:0019221//cytokine-mediated signaling pathway;GO:0021537//telencephalon development;GO:0022610;GO:0007626//locomotory behavior;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0007276//gamete generation;GO:0001525//angiogenesis;GO:0003013//circulatory system process;GO:0006950//response to stress;GO:0043066//negative regulation of apoptotic process;GO:0042110//T cell activation;GO:0030832//regulation of actin filament length;GO:0006816//calcium ion transport;GO:0006875//cellular metal ion homeostasis;GO:0051707//response to other organism;GO:0009725//response to hormone;GO:0009887//organ morphogenesis;GO:0050927//positive regulation of positive chemotaxis;GO:0045773//positive regulation of axon extension;GO:0014046;GO:0001935//endothelial cell proliferation;GO:0007411//axon guidance;GO:0003006//developmental process involved in reproduction;GO:0019221//cytokine-mediated signaling pathway;GO:0021537//telencephalon development;GO:0007626//locomotory behavior;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0007276//gamete generation;GO:0001525//angiogenesis;GO:0043066//negative regulation of apoptotic process;GO:0042110//T cell activation;GO:0006816//calcium ion transport;GO:0009887//organ morphogenesis;GO:0050927//positive regulation of positive chemotaxis;GO:0045773//positive regulation of axon extension "gi|148667157|gb|EDK99573.1|/4.24114e-51/chemokine (C-X-C motif) ligand 12, isoform CRA_c, partial [Mus musculus]" 19359 3827 55.84666667 52.27333333 -0.095396014 Down 0.26506262 Rad23b "RAD23 homolog B, nucleotide excision repair protein" K10839|1|5e-118|428|mmu:19359|UV excision repair protein RAD23 GO:0031981//nuclear lumen;GO:0000109//nucleotide-excision repair complex GO:0043130//ubiquitin binding;GO:0003677//DNA binding GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006281//DNA repair;GO:0061136//regulation of proteasomal protein catabolic process;GO:0051276//chromosome organization;GO:0048232//male gamete generation gi|74178713|dbj|BAE34014.1|/4.61553e-117/unnamed protein product [Mus musculus] 11790 9109.08 52.1 48.53666667 -0.10220834 Down 0.265015608 Speg SPEG complex locus K08809|1|6e-73|277|tup:102478618|striated muscle-specific serine/threonine protein kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550 GO:0048731//system development;GO:0055001//muscle cell development;GO:0048731//system development;GO:0055001//muscle cell development;GO:0048731//system development;GO:0055001//muscle cell development "gi|148667988|gb|EDL00405.1|/0/SPEG complex locus, isoform CRA_b, partial [Mus musculus]" 16399 3437 0.126666667 0.306666667 1.275634443 Up 0.264996803 Itga2b integrin alpha 2b K06476|1|0.0|1973|mmu:16399|integrin alpha 2B GO:0005924//cell-substrate adherens junction;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface GO:0043169//cation binding;GO:0032403//protein complex binding GO:0007166//cell surface receptor signaling pathway;GO:0031589//cell-substrate adhesion;GO:0030168//platelet activation gi|159110663|ref|NP_034705.2|/0/integrin alpha-IIb precursor [Mus musculus] 68184 2236 16.78333333 15.49666667 -0.115071352 Down 0.264987401 Denr density-regulated protein - - "GO:0008135//translation factor activity, RNA binding" GO:0006412//translation gi|4755083|gb|AAC02985.2|/8.57807e-86/density regulated protein drp1 [Homo sapiens] 66980 2197.52 10.88666667 11.91333333 0.130014843 Up 0.264987401 Zdhhc6 "zinc finger, DHHC domain containing 6" K20031|1|0.0|839|mmu:66980|palmitoyltransferase ZDHHC6 [EC:2.3.1.225] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0016740//transferase activity;GO:0046914//transition metal ion binding;GO:0016740//transferase activity - "gi|148669781|gb|EDL01728.1|/0/mCG18121, isoform CRA_c, partial [Mus musculus]" 217342 5192 12.23666667 11.21 -0.126424336 Down 0.264987401 Ube2o ubiquitin-conjugating enzyme E2O K10581|1|0.0|2164|mmu:217342|ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24] - - - "gi|148702637|gb|EDL34584.1|/0/ubiquitin-conjugating enzyme E2O, partial [Mus musculus]" 50907 5463.25 14.9 16.19333333 0.120087659 Up 0.264987401 Preb prolactin regulatory element binding K14003|1|2e-166|590|mmu:50907|prolactin regulatory element-binding protein GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006810//transport;GO:0045184//establishment of protein localization;GO:0006351//transcription, DNA-templated;GO:0006810//transport;GO:0045184//establishment of protein localization;GO:0006351//transcription, DNA-templated" gi|158749640|ref|NP_057912.2|/0/prolactin regulatory element-binding protein isoform 1 [Mus musculus] 11512 6038 53.9 50.37 -0.097720542 Down 0.264949791 Adcy6 adenylate cyclase 6 K08046|1|0.0|2223|mmu:11512|adenylate cyclase 6 [EC:4.6.1.1] GO:0043231//intracellular membrane-bounded organelle;GO:0005902//microvillus;GO:0031224//intrinsic component of membrane;GO:0005886//plasma membrane GO:0032550;GO:0004016//adenylate cyclase activity;GO:0043169//cation binding;GO:0019900//kinase binding GO:0007186//G-protein coupled receptor signaling pathway;GO:0071407//cellular response to organic cyclic compound;GO:0045762//positive regulation of adenylate cyclase activity;GO:0034695//response to prostaglandin E gi|86604721|ref|NP_031431.2|/0/adenylate cyclase type 6 [Mus musculus] 225358 3359 1.553333333 1.22 -0.348486306 Down 0.264912182 Fam13b "family with sequence similarity 13, member B" K18470|1|1e-18|98.6|cmy:102937835|Rho GTPase-activating protein 1 - - - - 242851 1174 0.173333333 0.363333333 1.067744607 Up 0.264771146 Gnat3 "guanine nucleotide binding protein, alpha transducing 3" K19729|1|0.0|676|mmu:242851|guanine nucleotide-binding protein G(t) subunit alpha 3 - - - gi|124487259|ref|NP_001074612.1|/0/guanine nucleotide-binding protein G(t) subunit alpha-3 [Mus musculus] 70225 986.77 8.283333333 9.153333333 0.144085774 Up 0.264742939 Ppil3 peptidylprolyl isomerase (cyclophilin)-like 3 K12734|1|3e-92|340|mmu:70225|peptidyl-prolyl cis-trans isomerase-like 3 [EC:5.2.1.8] GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0016859//cis-trans isomerase activity;GO:0005488//binding;GO:0016859//cis-trans isomerase activity;GO:0005488//binding;GO:0016859//cis-trans isomerase activity;GO:0005488//binding;GO:0016859//cis-trans isomerase activity;GO:0005488//binding GO:0000377;GO:0044267//cellular protein metabolic process;GO:0000377;GO:0044267//cellular protein metabolic process;GO:0000377;GO:0044267//cellular protein metabolic process;GO:0000377;GO:0044267//cellular protein metabolic process "gi|148667663|gb|EDL00080.1|/2.53052e-99/peptidylprolyl isomerase (cyclophilin)-like 3, isoform CRA_c, partial [Mus musculus]" 75914 5440 5.626666667 4.996666667 -0.171314521 Down 0.264733536 Exoc6b exocyst complex component 6B K19985|1|0.0|1556|mmu:75914|exocyst complex component 6 GO:0043234//protein complex - GO:0045184//establishment of protein localization;GO:0006887//exocytosis gi|226371698|ref|NP_796051.2|/0/exocyst complex component 6B [Mus musculus] 110816 3871 5.633333333 5.003333333 -0.17109927 Down 0.264733536 Pwp2 PWP2 periodic tryptophan protein homolog (yeast) K14558|1|0.0|1729|mmu:110816|periodic tryptophan protein 2 GO:0043231//intracellular membrane-bounded organelle - - gi|30102930|ref|NP_083822.1|/0/periodic tryptophan protein 2 homolog [Mus musculus] 66369 1910 5.646666667 5.013333333 -0.171629308 Down 0.264733536 Dus2 dihydrouridine synthase 2 K05543|1|0.0|940|mmu:66369|tRNA-dihydrouridine synthase 2 [EC:1.3.1.91] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0003723//RNA binding;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0000166//nucleotide binding" GO:0006399//tRNA metabolic process;GO:0044710;GO:0006399//tRNA metabolic process;GO:0044710 gi|110625595|ref|NP_079794.1|/0/tRNA-dihydrouridine(20) synthase [NAD(P)+]-like isoform 1 [Mus musculus] 103889 1631 0.82 0.563333333 -0.541635069 Down 0.264686525 Hoxb2 homeobox B2 K09302|1|8e-162|572|mmu:103889|homeobox protein HoxA/B2 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0003002//regionalization;GO:0001501//skeletal system development;GO:0048562//embryonic organ morphogenesis;GO:0021604;GO:0006351//transcription, DNA-templated;GO:0021546//rhombomere development;GO:0002009//morphogenesis of an epithelium" gi|94158904|ref|NP_598793.2|/7.12643e-161/homeobox protein Hox-B2 [Mus musculus] 110208 2224 22.68333333 24.52666667 0.112718515 Up 0.264677122 Pgd phosphogluconate dehydrogenase K00033|1|0.0|916|mmu:110208|6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] GO:0043227//membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0043168//anion binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0048037//cofactor binding" GO:0019520;GO:0006098//pentose-phosphate shunt;GO:0019321 "gi|124486895|ref|NP_001074743.1|/0/6-phosphogluconate dehydrogenase, decarboxylating [Mus musculus]" 20481 5481 25.55 23.71 -0.107827628 Down 0.264677122 Ski ski sarcoma viral oncogene homolog (avian) K18499|1|5e-90|336|cmk:103185104|Ski-like protein - - - gi|113205055|ref|NP_035515.2|/0/ski oncogene [Mus musculus] 622320 2975 1.95 2.343333333 0.265088065 Up 0.264592501 Kctd21 potassium channel tetramerisation domain containing 21 "K03849|1|1e-37|161|cmk:103177229|alpha-1,3-glucosyltransferase [EC:2.4.1.265];K15074|2|4e-16|89.7|ocu:100339870|BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein;K11835|3|8e-16|89.0|sko:100377510|ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.4.19.12]" - - - gi|625217933|ref|XP_007649206.1|/9.05659e-150/PREDICTED: BTB/POZ domain-containing protein KCTD21 [Cricetulus griseus] 100041231 632 1.89 2.28 0.27064759 Up 0.264592501 Gm3219 B-cell CLL/lymphoma 7C pseudogene - - - GO:0012501//programmed cell death "gi|148685626|gb|EDL17573.1|/3.10655e-44/B-cell CLL/lymphoma 7C, isoform CRA_c [Mus musculus]" 20350 3346.17 11.70666667 10.69 -0.131068491 Down 0.264442063 Sema3f "sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F" K06840|1|0.0|1469|mmu:20350|semaphorin 3 - - GO:0030517//negative regulation of axon extension;GO:0006935//chemotaxis gi|31543683|ref|NP_035479.2|/0/semaphorin-3F isoform 2 precursor [Mus musculus] 171567 1753.33 11.90666667 10.88333333 -0.129649089 Down 0.264442063 Nme7 NME/NM23 family member 7 K00940|1|0.0|801|mmu:171567|nucleoside-diphosphate kinase [EC:2.7.4.6] GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center "GO:0032550;GO:0043169//cation binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032550;GO:0043169//cation binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032550;GO:0043169//cation binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0009209;GO:0007417//central nervous system development;GO:0010970//transport along microtubule;GO:0009152//purine ribonucleotide biosynthetic process;GO:0009855//determination of bilateral symmetry;GO:0003341//cilium movement;GO:0003002//regionalization;GO:0007224//smoothened signaling pathway;GO:0009132//nucleoside diphosphate metabolic process;GO:0009209;GO:0007417//central nervous system development;GO:0010970//transport along microtubule;GO:0009152//purine ribonucleotide biosynthetic process;GO:0009855//determination of bilateral symmetry;GO:0003341//cilium movement;GO:0003002//regionalization;GO:0007224//smoothened signaling pathway;GO:0009132//nucleoside diphosphate metabolic process;GO:0009209;GO:0007417//central nervous system development;GO:0010970//transport along microtubule;GO:0009152//purine ribonucleotide biosynthetic process;GO:0009855//determination of bilateral symmetry;GO:0003341//cilium movement;GO:0003002//regionalization;GO:0007224//smoothened signaling pathway;GO:0009132//nucleoside diphosphate metabolic process "gi|148707306|gb|EDL39253.1|/0/non-metastatic cells 7, protein expressed in, isoform CRA_a, partial [Mus musculus]" 66488 1634 14.65666667 15.92666667 0.119887321 Up 0.264442063 Fam136a "family with sequence similarity 136, member A" - GO:0043231//intracellular membrane-bounded organelle - - gi|13385042|ref|NP_079867.1|/5.61165e-73/protein FAM136A [Mus musculus] 227697 2126 10.90333333 11.92 0.128614977 Up 0.264442063 Dolk dolichol kinase K00902|1|0.0|916|mmu:227697|dolichol kinase [EC:2.7.1.108] GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0016301//kinase activity GO:0008654//phospholipid biosynthetic process gi|29244058|ref|NP_808316.1|/0/dolichol kinase [Mus musculus] 212880 5715 6.426666667 5.736666667 -0.163857954 Down 0.26443266 Ddx46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 K12811|1|0.0|1447|mmu:212880|ATP-dependent RNA helicase DDX46/PRP5 [EC:3.6.4.13] GO:0016604//nuclear body "GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled" GO:0006396//RNA processing gi|530585119|ref|NP_001268984.1|/0/probable ATP-dependent RNA helicase DDX46 [Mus musculus] 56406 6872 6.743333333 6.053333333 -0.155732117 Down 0.26443266 Ncoa6 nuclear receptor coactivator 6 K14971|1|0.0|3206|rno:116464|nuclear receptor coactivator 6 GO:0031981//nuclear lumen;GO:0034708;GO:0031981//nuclear lumen;GO:0034708 GO:0005102//receptor binding;GO:0003713//transcription coactivator activity;GO:0042802//identical protein binding;GO:0008134//transcription factor binding;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0042802//identical protein binding;GO:0035258//steroid hormone receptor binding GO:0030097//hemopoiesis;GO:0048568//embryonic organ development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007417//central nervous system development;GO:0033554//cellular response to stress;GO:0030097//hemopoiesis;GO:0048568//embryonic organ development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007417//central nervous system development;GO:0006259//DNA metabolic process;GO:0006629//lipid metabolic process;GO:0009719;GO:0033554//cellular response to stress;GO:0031958 gi|336020351|ref|NP_001229487.1|/0/nuclear receptor coactivator 6 isoform 2 [Mus musculus] 29806 4864 23.1 24.92 0.109411217 Up 0.264319832 Limd1 LIM domains containing 1 K16682|1|0.0|1347|mmu:29806|LIM domain-containing protein GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0031332//RNAi effector complex;GO:0005924//cell-substrate adherens junction GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity "GO:0006351//transcription, DNA-templated;GO:0022604//regulation of cell morphogenesis;GO:0001649//osteoblast differentiation;GO:0022618//ribonucleoprotein complex assembly;GO:0006796//phosphate-containing compound metabolic process;GO:0048870//cell motility;GO:0006996//organelle organization;GO:0030178//negative regulation of Wnt signaling pathway;GO:0035195//gene silencing by miRNA;GO:0006950//response to stress" gi|224994267|ref|NP_038888.2|/0/LIM domain-containing protein 1 [Mus musculus] 67213 3352 8.29 9.15 0.142399642 Up 0.264178796 Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 - GO:0031224//intrinsic component of membrane;GO:0044421 GO:0005102//receptor binding GO:0042221//response to chemical "gi|148677351|gb|EDL09298.1|/6.18329e-94/CKLF-like MARVEL transmembrane domain containing 6, partial [Mus musculus]" 65970 4148.91 9.133333333 8.27 -0.143254158 Down 0.264178796 Lima1 LIM domain and actin binding 1 K19947|1|1e-14|85.5|aqu:105311991|protein-methionine sulfoxide oxidase MICAL [EC:1.14.13.-] - - - - 78883 1072 0.373333333 0.18 -1.05246742 Down 0.264169393 9630013K17Rik RIKEN cDNA 9630013K17 gene - - - - - 73906 1319 0.36 0.173333333 -1.054447784 Down 0.264169393 4833417C18Rik RIKEN cDNA 4833417C18 gene - - - - - 20612 6427 1.663333333 1.326666667 -0.326271385 Down 0.264159991 Siglec1 "sialic acid binding Ig-like lectin 1, sialoadhesin" K06548|1|0.0|3231|mmu:20612|sialoadhesin GO:0031224//intrinsic component of membrane - GO:0022610;GO:0016192//vesicle-mediated transport gi|226958332|ref|NP_035556.3|/0/sialoadhesin precursor [Mus musculus] 213945 4230 0.516666667 0.296666667 -0.800390974 Down 0.264112979 Col28a1 "collagen, type XXVIII, alpha 1" "K06238|1|1e-43|181|ccw:104694607|collagen, type VI, alpha" GO:0005578//proteinaceous extracellular matrix GO:0030414//peptidase inhibitor activity - gi|83745131|ref|NP_001032954.1|/0/collagen alpha-1(XXVIII) chain precursor [Mus musculus] 75458 571 0.303333333 0.526666667 0.795986108 Up 0.264112979 Cklf chemokine-like factor - GO:0044421;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0031224//intrinsic component of membrane GO:0005125//cytokine activity;GO:0005125//cytokine activity;GO:0005125//cytokine activity;GO:0005125//cytokine activity GO:0030595//leukocyte chemotaxis;GO:0046903//secretion;GO:0030595//leukocyte chemotaxis;GO:0046903//secretion;GO:0030595//leukocyte chemotaxis;GO:0046903//secretion;GO:0030595//leukocyte chemotaxis;GO:0046903//secretion gi|21312956|ref|NP_083571.1|/8.64998e-83/chemokine-like factor isoform 1 [Mus musculus] 23921 2900.02 0.29 0.506666667 0.804984018 Up 0.264112979 Sh2b2 SH2B adaptor protein 2 K07193|1|0.0|1035|mmu:23921|SH2B adapter protein 2 GO:0016020//membrane;GO:0032432//actin filament bundle;GO:0031252//cell leading edge;GO:0016020//membrane;GO:0032432//actin filament bundle;GO:0031252//cell leading edge;GO:0016020//membrane;GO:0032432//actin filament bundle;GO:0031252//cell leading edge "GO:0060089;GO:0030674//protein binding, bridging;GO:0008289//lipid binding;GO:0060089;GO:0030674//protein binding, bridging;GO:0008289//lipid binding;GO:0060089;GO:0030674//protein binding, bridging;GO:0008289//lipid binding" GO:0048731//system development;GO:0001782//B cell homeostasis;GO:0007010//cytoskeleton organization;GO:0007265//Ras protein signal transduction;GO:0007259//JAK-STAT cascade;GO:0045444//fat cell differentiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008152//metabolic process;GO:0002429//immune response-activating cell surface receptor signaling pathway;GO:0048731//system development;GO:0001782//B cell homeostasis;GO:0007010//cytoskeleton organization;GO:0007265//Ras protein signal transduction;GO:0007259//JAK-STAT cascade;GO:0045444//fat cell differentiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008152//metabolic process;GO:0002429//immune response-activating cell surface receptor signaling pathway;GO:0048731//system development;GO:0001782//B cell homeostasis;GO:0007010//cytoskeleton organization;GO:0007265//Ras protein signal transduction;GO:0007259//JAK-STAT cascade;GO:0045444//fat cell differentiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008152//metabolic process;GO:0002429//immune response-activating cell surface receptor signaling pathway "gi|148687368|gb|EDL19315.1|/0/SH2B adaptor protein 2, isoform CRA_c, partial [Mus musculus]" 233046 4599 2.743333333 3.203333333 0.223644 Up 0.264065967 Rasgrp4 RAS guanyl releasing protein 4 K12363|1|0.0|1015|mmu:233046|RAS guanyl-releasing protein 4 GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0009605//response to external stimulus;GO:0040007//growth;GO:0048869//cellular developmental process;GO:0007265//Ras protein signal transduction;GO:0009605//response to external stimulus;GO:0040007//growth;GO:0048869//cellular developmental process;GO:0007265//Ras protein signal transduction;GO:0009605//response to external stimulus;GO:0040007//growth;GO:0048869//cellular developmental process;GO:0007265//Ras protein signal transduction gi|74185872|dbj|BAE32802.1|/0/unnamed protein product [Mus musculus] 19387 2954 14.53666667 15.79333333 0.119619208 Up 0.264047162 Rangap1 RAN GTPase activating protein 1 K14319|1|0.0|972|mmu:19387|Ran GTPase-activating protein 1 "GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0044444//cytoplasmic part" - GO:0006611//protein export from nucleus;GO:0007154//cell communication;GO:0006611//protein export from nucleus;GO:0007154//cell communication "gi|148672614|gb|EDL04561.1|/0/RAN GTPase activating protein 1, isoform CRA_b, partial [Mus musculus]" 109905 2474 14.65666667 15.92 0.119283304 Up 0.264047162 Rap1a RAS-related protein-1a K04353|1|4e-85|318|gja:107112269|Ras-related protein Rap-1A GO:0016020//membrane;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0031267//small GTPase binding GO:0015980//energy derivation by oxidation of organic compounds;GO:0007599//hemostasis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006468//protein phosphorylation;GO:0030073//insulin secretion;GO:0009154//purine ribonucleotide catabolic process;GO:0001775//cell activation;GO:0035556//intracellular signal transduction gi|565309092|gb|ETE62745.1|/3.01294e-87/Ras-related protein Rap-1A [Ophiophagus hannah] 98733 5261.04 23.55333333 21.75 -0.114915848 Down 0.26403776 Obsl1 obscurin-like 1 K19574|1|0.0|3467|mmu:98733|obscurin-like protein 1 - - - gi|893548264|ref|NP_001297608.1|/0/obscurin-like protein 1 isoform 2 [Mus musculus] 232910 798 46.54 49.84666667 0.099025822 Up 0.264018955 Ap2s1 "adaptor-related protein complex 2, sigma 1 subunit" K11827|1|6e-77|289|lcm:102359311|AP-2 complex subunit sigma-1 GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0030128//clathrin coat of endocytic vesicle GO:0022892//substrate-specific transporter activity GO:0007267//cell-cell signaling;GO:0006901//vesicle coating;GO:0015031//protein transport;GO:0044764;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0050688//regulation of defense response to virus;GO:0006897//endocytosis;GO:0006935//chemotaxis;GO:0002478 gi|803246877|ref|XP_011983440.1|/3.53501e-85/PREDICTED: AP-2 complex subunit sigma isoform X2 [Ovis aries musimon] 13800 12268.03 11.60666667 10.6 -0.130889437 Down 0.263971943 Enah enabled homolog (Drosophila) K05746|1|1e-92|345|mmu:13800|enabled GO:0005856//cytoskeleton;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0042995//cell projection;GO:0005856//cytoskeleton;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0042995//cell projection;GO:0005856//cytoskeleton;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0042995//cell projection;GO:0005856//cytoskeleton;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0042995//cell projection GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding GO:0014020;GO:0006810//transport;GO:0048869//cellular developmental process;GO:0007015//actin filament organization;GO:0006935//chemotaxis;GO:0014020;GO:0006810//transport;GO:0048869//cellular developmental process;GO:0007015//actin filament organization;GO:0006935//chemotaxis;GO:0014020;GO:0006810//transport;GO:0048869//cellular developmental process;GO:0007015//actin filament organization;GO:0006935//chemotaxis;GO:0014020;GO:0006810//transport;GO:0048869//cellular developmental process;GO:0007015//actin filament organization;GO:0006935//chemotaxis gi|220500|dbj|BAA01570.1|/5.71671e-96/NDPP-1 protein [Mus musculus] 19718 1518 10.68666667 11.69666667 0.130285522 Up 0.263971943 Rfc2 replication factor C (activator 1) 2 K10755|1|0.0|697|mmu:19718|replication factor C subunit 2/4 GO:0005657//replication fork;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0016462//pyrophosphatase activity;GO:0032550 GO:0006259//DNA metabolic process gi|11177922|ref|NP_064406.1|/0/replication factor C subunit 2 [Mus musculus] 27364 3685.9 11.85 10.83666667 -0.128966004 Down 0.263971943 Srr serine racemase K12235|1|0.0|646|mmu:27364|serine racemase [EC:5.1.1.18] GO:0016020//membrane;GO:0044297//cell body;GO:0044424;GO:0016020//membrane;GO:0044297//cell body;GO:0044424 GO:0032550;GO:0047661//amino-acid racemase activity;GO:0016597//amino acid binding;GO:0046872//metal ion binding;GO:0016841//ammonia-lyase activity;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0032550;GO:0047661//amino-acid racemase activity;GO:0016597//amino acid binding;GO:0046872//metal ion binding;GO:0016841//ammonia-lyase activity;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding GO:0007417//central nervous system development;GO:0006090//pyruvate metabolic process;GO:0014072//response to isoquinoline alkaloid;GO:0009070//serine family amino acid biosynthetic process;GO:0044767//single-organism developmental process;GO:0051260//protein homooligomerization;GO:0002237//response to molecule of bacterial origin;GO:0007417//central nervous system development;GO:0006090//pyruvate metabolic process;GO:0014072//response to isoquinoline alkaloid;GO:0009070//serine family amino acid biosynthetic process;GO:0044767//single-organism developmental process;GO:0051260//protein homooligomerization;GO:0002237//response to molecule of bacterial origin gi|7305521|ref|NP_038789.1|/0/serine racemase [Mus musculus] 67553 2633 0.523333333 0.303333333 -0.786826109 Down 0.263896724 Gstcd "glutathione S-transferase, C-terminal domain containing" - - - - "gi|148680240|gb|EDL12187.1|/0/glutathione S-transferase, C-terminal domain containing, isoform CRA_c, partial [Mus musculus]" 56410 4723 0.3 0.52 0.793549123 Up 0.263896724 Cbln3 cerebellin 3 precursor protein K18744|1|1e-13|82.4|xma:102217643|caprin-2 GO:0044421 - - "gi|148704285|gb|EDL36232.1|/7.90187e-90/cerebellin 3 precursor protein, isoform CRA_b, partial [Mus musculus]" 117590 2311.77 44.28333333 47.56333333 0.103086004 Up 0.263877919 Asb10 ankyrin repeat and SOCS box-containing 10 K10332|1|0.0|917|mmu:117590|ankyrin repeat and SOCS box protein 10 - - GO:0032446//protein modification by small protein conjugation;GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation gi|17978258|ref|NP_536692.1|/0/ankyrin repeat and SOCS box protein 10 isoform 1 [Mus musculus] 226409 4211.52 0.75 1.033333333 0.462343214 Up 0.263830908 Zranb3 "zinc finger, RAN-binding domain containing 3" K14440|1|2e-99|367|nve:NEMVE_v1g80671|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:3.6.4.12] GO:0043231//intracellular membrane-bounded organelle;GO:0005657//replication fork;GO:0043231//intracellular membrane-bounded organelle;GO:0005657//replication fork GO:0046914//transition metal ion binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0031593//polyubiquitin binding;GO:0003676//nucleic acid binding;GO:0004519//endonuclease activity;GO:0046914//transition metal ion binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0031593//polyubiquitin binding;GO:0003676//nucleic acid binding;GO:0004519//endonuclease activity GO:0000018//regulation of DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0009416//response to light stimulus;GO:0045005//DNA-dependent DNA replication maintenance of fidelity;GO:0032392//DNA geometric change;GO:0000018//regulation of DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0009416//response to light stimulus;GO:0045005//DNA-dependent DNA replication maintenance of fidelity;GO:0032392//DNA geometric change "gi|148707811|gb|EDL39758.1|/0/mCG13937, isoform CRA_b, partial [Mus musculus]" 110332 2476 1.033333333 0.753333333 -0.455945443 Down 0.263830908 Pp2d1 protein phosphatase 2C-like domain containing 1 K16340|1|1e-10|71.6|cfa:476179|PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16];K17499|2|1e-09|68.2|hmg:100208679|protein phosphatase 1G [EC:3.1.3.16] - - - - 73426 531 0.583333333 0.356666667 -0.709744125 Down 0.2638027 1700066B17Rik RIKEN cDNA 1700066B17 gene - - - - gi|148682619|gb|EDL14566.1|/7.52722e-14/mCG65746 [Mus musculus] 22718 3863 1.126666667 1.446666667 0.360671796 Up 0.263765091 Zfp60 zinc finger protein 60 K09228|1|0.0|1480|mmu:22718|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|86476064|ref|NP_083807.2|/0/zinc finger protein 60 [Mus musculus] 100043497 1276 0.133333333 0.313333333 1.232660757 Up 0.263699274 Nat8f7 N-acetyltransferase 8 (GCN5-related) family member 7 K18309|1|2e-17|92.8|dre:564754|aspartate N-acetyltransferase [EC:2.3.1.17] - - - - 77644 3340 3.976666667 3.47 -0.196623974 Down 0.263699274 C330007P06Rik RIKEN cDNA C330007P06 gene "K10214|1|3e-15|87.4|oaa:100074731|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase [EC:1.17.99.3]" - - - gi|74200778|dbj|BAE24768.1|/4.70381e-102/unnamed protein product [Mus musculus] 223723 3770 4.003333333 3.493333333 -0.196597434 Down 0.263699274 Ttll12 "tubulin tyrosine ligase-like family, member 12" K16609|1|0.0|1296|mmu:223723|tubulin--tyrosine ligase-like protein 12 - GO:0016881//acid-amino acid ligase activity GO:0036211//protein modification process "gi|148672520|gb|EDL04467.1|/0/tubulin tyrosine ligase-like family, member 12 [Mus musculus]" 21422 3301 4.016666667 3.503333333 -0.197270477 Down 0.263699274 Tfcp2 transcription factor CP2 K09275|1|0.0|958|mmu:21422|transcription factor CP2 and related proteins GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter "gi|148672133|gb|EDL04080.1|/0/transcription factor CP2, isoform CRA_a, partial [Mus musculus]" 231452 5020 2.966666667 2.53 -0.22970545 Down 0.263680469 Sdad1 SDA1 domain containing 1 K14856|1|0.0|1131|mmu:231452|protein SDA1 GO:0031981//nuclear lumen - GO:0045184//establishment of protein localization;GO:0007010//cytoskeleton organization;GO:0000054//ribosomal subunit export from nucleus gi|27370042|ref|NP_766301.1|/0/protein SDA1 homolog [Mus musculus] 56459 1986.68 14.41666667 15.66333333 0.119653635 Up 0.263680469 Sae1 SUMO1 activating enzyme subunit 1 K10684|1|1e-177|625|mmu:56459|ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0008641//small protein activating enzyme activity;GO:0036094//small molecule binding;GO:0046983//protein dimerization activity;GO:0030234//enzyme regulator activity;GO:0008641//small protein activating enzyme activity;GO:0036094//small molecule binding;GO:0046983//protein dimerization activity;GO:0030234//enzyme regulator activity;GO:0008641//small protein activating enzyme activity;GO:0036094//small molecule binding;GO:0046983//protein dimerization activity;GO:0030234//enzyme regulator activity GO:0032446//protein modification by small protein conjugation;GO:0044093;GO:0032446//protein modification by small protein conjugation;GO:0044093;GO:0032446//protein modification by small protein conjugation;GO:0044093 gi|552953784|ref|NP_001272821.1|/1.08938e-162/SUMO-activating enzyme subunit 1 isoform b [Mus musculus] 30805 2260 2.21 2.623333333 0.247354765 Up 0.263671067 Slc22a4 "solute carrier family 22 (organic cation transporter), member 4" "K08202|1|0.0|1076|mmu:30805|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 4/5" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044459 GO:0032550;GO:0019904//protein domain specific binding;GO:0015101//organic cation transmembrane transporter activity;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015298//solute:cation antiporter activity GO:0044763;GO:0006639//acylglycerol metabolic process;GO:0006577//amino-acid betaine metabolic process;GO:0030001//metal ion transport gi|9790129|ref|NP_062661.1|/0/solute carrier family 22 member 4 [Mus musculus] 66140 1349 2.18 2.593333333 0.250479519 Up 0.263671067 Ska2 spindle and kinetochore associated complex subunit 2 - GO:0005819//spindle;GO:0000777//condensed chromosome kinetochore GO:0015631//tubulin binding GO:0031109//microtubule polymerization or depolymerization;GO:0007067//mitotic nuclear division gi|13384752|ref|NP_079653.1|/1.35556e-42/spindle and kinetochore-associated protein 2 [Mus musculus] 16580 2627 0.183333333 0.373333333 1.025995209 Up 0.263652262 Kifc5b kinesin family member C5B K10405|1|0.0|1186|mmu:16580|kinesin family member C1 GO:0015630//microtubule cytoskeleton;GO:0005768//endosome GO:0032550;GO:0003774//motor activity GO:0000087//mitotic M phase;GO:0006928//movement of cell or subcellular component gi|116642893|ref|NP_444403.2|/0/kinesin family member C5B [Mus musculus] 14177 1232 0.37 0.183333333 -1.013056153 Down 0.263652262 Fgf6 fibroblast growth factor 6 K04358|1|2e-107|391|mmu:14177|fibroblast growth factor GO:0005886//plasma membrane GO:0005102//receptor binding GO:0016337//single organismal cell-cell adhesion;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0042692//muscle cell differentiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048522;GO:0008283//cell proliferation gi|112363076|ref|NP_034334.1|/1.52475e-106/fibroblast growth factor 6 precursor [Mus musculus] 67459 9392 4.33 4.913333333 0.182335094 Up 0.263558238 Nvl nuclear VCP-like K14571|1|0.0|1513|mmu:67459|ribosome biogenesis ATPase - - - - 224794 4558 5.026666667 4.446666667 -0.176877762 Down 0.263558238 Enpp4 ectonucleotide pyrophosphatase/phosphodiesterase 4 K18424|1|0.0|939|mmu:224794|ectonucleotide pyrophosphatase/phosphodiesterase family member 4 [EC:3.6.1.29] GO:0031224//intrinsic component of membrane GO:0003824//catalytic activity - gi|568999997|ref|XP_006524196.1|/0/PREDICTED: bis(5'-adenosyl)-triphosphatase enpp4 isoform X3 [Mus musculus] 72323 2129 4.336666667 4.913333333 0.180115562 Up 0.263558238 Asb6 ankyrin repeat and SOCS box-containing 6 K10328|1|0.0|845|mmu:72323|ankyrin repeat and SOCS box protein 6 GO:0044424 - GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation gi|19111154|ref|NP_579924.1|/0/ankyrin repeat and SOCS box protein 6 [Mus musculus] 72103 3155 4.413333333 4.996666667 0.179097261 Up 0.263558238 Aplf aprataxin and PNKP like factor K13295|1|0.0|910|mmu:72103|aprataxin and PNK-like factor [EC:4.2.99.18] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004527//exonuclease activity;GO:0004519//endonuclease activity;GO:0043169//cation binding;GO:0036094//small molecule binding;GO:0016835//carbon-oxygen lyase activity;GO:0004527//exonuclease activity;GO:0004519//endonuclease activity;GO:0043169//cation binding;GO:0036094//small molecule binding;GO:0016835//carbon-oxygen lyase activity GO:0006281//DNA repair;GO:0006281//DNA repair gi|281427262|ref|NP_001163960.1|/0/aprataxin and PNK-like factor isoform 1 [Mus musculus] 80743 3206 8.01 8.856666667 0.144961579 Up 0.263473617 Vps16 VSP16 CORVET/HOPS core subunit K20180|1|0.0|1562|mmu:80743|vacuolar protein sorting-associated protein 16 GO:0005770//late endosome;GO:0043005//neuron projection;GO:0005764//lysosome;GO:0005774//vacuolar membrane;GO:0044297//cell body;GO:0015629//actin cytoskeleton GO:0003779//actin binding GO:0015031//protein transport gi|254939640|ref|NP_085036.3|/0/vacuolar protein sorting-associated protein 16 homolog [Mus musculus] 69721 4701.69 8.59 9.44 0.136128728 Up 0.263473617 Nkiras1 NFKB inhibitor interacting Ras-like protein 1 K17197|1|5e-94|349|mmu:69721|NF-kappa-B inhibitor-interacting Ras-like protein - - - - 12519 1701 0.06 0.22 1.874469118 Up 0.263436007 Cd80 CD80 antigen K05412|1|9e-164|579|mmu:12519|CD80 antigen GO:0031224//intrinsic component of membrane;GO:0009986//cell surface - GO:0042102//positive regulation of T cell proliferation;GO:0001934//positive regulation of protein phosphorylation;GO:0031294//lymphocyte costimulation "gi|148665565|gb|EDK97981.1|/4.1069e-167/CD80 antigen, isoform CRA_a [Mus musculus]" 238317 6914.57 6.61 5.926666667 -0.157429353 Down 0.2634078 Elmsan1 ELM2 and Myb/SANT-like domain containing 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|254553410|ref|NP_001156973.1|/0/ELM2 and SANT domain-containing protein 1 [Mus musculus] 22083 4317 6.383333333 5.706666667 -0.16166169 Down 0.2634078 Ctr9 "CTR9 homolog, Paf1/RNA polymerase II complex component" K15176|1|0.0|1643|mmu:22083|RNA polymerase-associated protein CTR9 - - - - 18472 5550.47 22.48333333 24.25333333 0.1093271 Up 0.2634078 Pafah1b1 "platelet-activating factor acetylhydrolase, isoform 1b, subunit 1" K16794|1|0.0|850|oaa:100078186|platelet-activating factor acetylhydrolase IB subunit alpha "GO:0005818//aster;GO:0031981//nuclear lumen;GO:0072372//primary cilium;GO:0030424//axon;GO:0005875//microtubule associated complex;GO:0005635//nuclear envelope;GO:0005815//microtubule organizing center;GO:0000775//chromosome, centromeric region;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0005818//aster;GO:0031981//nuclear lumen;GO:0072372//primary cilium;GO:0030424//axon;GO:0005875//microtubule associated complex;GO:0005635//nuclear envelope;GO:0005815//microtubule organizing center;GO:0000775//chromosome, centromeric region;GO:0044444//cytoplasmic part;GO:0044297//cell body" GO:0016407//acetyltransferase activity;GO:0005539//glycosaminoglycan binding;GO:0042802//identical protein binding;GO:0015631//tubulin binding;GO:0019899//enzyme binding;GO:0045502//dynein binding;GO:0016407//acetyltransferase activity;GO:0005539//glycosaminoglycan binding;GO:0042802//identical protein binding;GO:0015631//tubulin binding;GO:0019899//enzyme binding;GO:0045502//dynein binding GO:0051301//cell division;GO:0003006//developmental process involved in reproduction;GO:0021952//central nervous system projection neuron axonogenesis;GO:0030316//osteoclast differentiation;GO:0040001//establishment of mitotic spindle localization;GO:0021543//pallium development;GO:0015031//protein transport;GO:0006998//nuclear envelope organization;GO:0016477//cell migration;GO:0044772//mitotic cell cycle phase transition;GO:0007254//JNK cascade;GO:0051642//centrosome localization;GO:0010975//regulation of neuron projection development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0007626//locomotory behavior;GO:0040023//establishment of nucleus localization;GO:0006650//glycerophospholipid metabolic process;GO:0030307//positive regulation of cell growth;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0051648//vesicle localization;GO:0007267//cell-cell signaling;GO:0050905//neuromuscular process;GO:0007067//mitotic nuclear division;GO:0009887//organ morphogenesis;GO:0008088//axo-dendritic transport;GO:0051301//cell division;GO:0003006//developmental process involved in reproduction;GO:0021952//central nervous system projection neuron axonogenesis;GO:0030316//osteoclast differentiation;GO:0040001//establishment of mitotic spindle localization;GO:0021543//pallium development;GO:0015031//protein transport;GO:0006998//nuclear envelope organization;GO:0016477//cell migration;GO:0044772//mitotic cell cycle phase transition;GO:0007254//JNK cascade;GO:0051642//centrosome localization;GO:0010975//regulation of neuron projection development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0007626//locomotory behavior;GO:0040023//establishment of nucleus localization;GO:0006650//glycerophospholipid metabolic process;GO:0030307//positive regulation of cell growth;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0051648//vesicle localization;GO:0007267//cell-cell signaling;GO:0050905//neuromuscular process;GO:0007067//mitotic nuclear division;GO:0009887//organ morphogenesis;GO:0008088//axo-dendritic transport gi|7305363|ref|NP_038653.1|/0/platelet-activating factor acetylhydrolase IB subunit alpha [Mus musculus] 58859 1577.29 5.816666667 6.493333333 0.158766641 Up 0.2634078 Efemp2 epidermal growth factor-containing fibulin-like extracellular matrix protein 2 K19866|1|0.0|878|mmu:58859|EGF-containing fibulin-like extracellular matrix protein 2 GO:0031012//extracellular matrix;GO:0031012//extracellular matrix GO:0046872//metal ion binding;GO:0038023//signaling receptor activity;GO:0046872//metal ion binding GO:0007599//hemostasis;GO:0007599//hemostasis gi|256355192|ref|NP_001157824.1|/0/EGF-containing fibulin-like extracellular matrix protein 2 isoform 2 precursor [Mus musculus] 16402 4440 23.59333333 21.82666667 -0.11228744 Down 0.2634078 Itga5 integrin alpha 5 (fibronectin receptor alpha) K06484|1|0.0|1929|rno:315346|integrin alpha 5 GO:0044424;GO:0009986//cell surface;GO:0001726//ruffle;GO:0005924//cell-substrate adherens junction;GO:0043234//protein complex;GO:0044421;GO:0005887//integral component of plasma membrane GO:0005172//vascular endothelial growth factor receptor binding;GO:0043169//cation binding "GO:0001934//positive regulation of protein phosphorylation;GO:0007166//cell surface receptor signaling pathway;GO:0007599//hemostasis;GO:0007611//learning or memory;GO:0043066//negative regulation of apoptotic process;GO:0016337//single organismal cell-cell adhesion;GO:0010810//regulation of cell-substrate adhesion;GO:0034329//cell junction assembly;GO:0044319//wound healing, spreading of cells;GO:0009967//positive regulation of signal transduction;GO:0006935//chemotaxis;GO:0002376//immune system process;GO:0048646//anatomical structure formation involved in morphogenesis" gi|930588918|ref|NP_034707.4|/0/integrin alpha-5 isoform 1 preproprotein [Mus musculus] 69928 930 0.536666667 0.313333333 -0.776328026 Down 0.263379593 Apitd1 "apoptosis-inducing, TAF9-like domain 1" K11511|1|3e-53|211|mmu:69928|centromere protein S "GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0000775//chromosome, centromeric region" GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity "GO:0006259//DNA metabolic process;GO:0000087//mitotic M phase;GO:0006351//transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus" "gi|148682904|gb|EDL14851.1|/2.34845e-52/RIKEN cDNA 2610040C18, isoform CRA_a [Mus musculus]" 330474 6107 11.42 10.42 -0.132207373 Down 0.263313776 Zc3h4 zinc finger CCCH-type containing 4 K15687|1|1e-07|63.2|cmk:103179053|E3 ubiquitin-protein ligase makorin [EC:2.3.2.27];K14404|3|8e-07|60.1|cfr:102511596|cleavage and polyadenylation specificity factor subunit 4 - - - gi|568946019|ref|XP_006540168.1|/0/PREDICTED: zinc finger CCCH domain-containing protein 4 isoform X4 [Mus musculus] 19735 3009 10.91 11.90666667 0.126118478 Up 0.263313776 Rgs2 regulator of G-protein signaling 2 K18154|1|2e-118|429|mmu:19735|regulator of G-protein signaling 2 - - - gi|31543586|ref|NP_033087.2|/1.57966e-117/regulator of G-protein signaling 2 [Mus musculus] 105782 5593.75 11.51 10.50666667 -0.131582799 Down 0.263313776 Scrib scribbled planar cell polarity K16175|1|0.0|2658|rno:362938|protein scribble GO:0043234//protein complex;GO:0044459;GO:0043209//myelin sheath;GO:0005911//cell-cell junction;GO:0044424;GO:0097060//synaptic membrane;GO:0043234//protein complex;GO:0044459;GO:0043209//myelin sheath;GO:0005911//cell-cell junction;GO:0044424;GO:0097060//synaptic membrane;GO:0043234//protein complex;GO:0044459;GO:0043209//myelin sheath;GO:0005911//cell-cell junction;GO:0044424;GO:0097060//synaptic membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0014020;GO:0001881//receptor recycling;GO:0006915//apoptotic process;GO:0006903//vesicle targeting;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0008104//protein localization;GO:0008347//glial cell migration;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0060443//mammary gland morphogenesis;GO:0000278//mitotic cell cycle;GO:0007155//cell adhesion;GO:0009611//response to wounding;GO:0014020;GO:0001881//receptor recycling;GO:0006915//apoptotic process;GO:0006903//vesicle targeting;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0008104//protein localization;GO:0008347//glial cell migration;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0060443//mammary gland morphogenesis;GO:0000278//mitotic cell cycle;GO:0007155//cell adhesion;GO:0009611//response to wounding;GO:0014020;GO:0001881//receptor recycling;GO:0006915//apoptotic process;GO:0006903//vesicle targeting;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0008104//protein localization;GO:0008347//glial cell migration;GO:0006935//chemotaxis;GO:0006897//endocytosis;GO:0060443//mammary gland morphogenesis;GO:0000278//mitotic cell cycle;GO:0007155//cell adhesion;GO:0009611//response to wounding gi|28972079|dbj|BAC65493.1|/0/mKIAA0147 protein [Mus musculus] 239126 1903 46.39 43.24 -0.101447323 Down 0.263163338 C1qtnf9 C1q and tumor necrosis factor related protein 9 "K19479|1|2e-50|203|acs:103280694|collagen, type X, alpha" - - - - 12716 1589 0.216666667 0.06 -1.852442812 Down 0.263125729 Ckmt1 "creatine kinase, mitochondrial 1, ubiquitous" K00933|1|0.0|771|mmu:12716|creatine kinase [EC:2.7.3.2] GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0032550;GO:0016301//kinase activity GO:0006603//phosphocreatine metabolic process "gi|148696104|gb|EDL28051.1|/0/creatine kinase, mitochondrial 1, ubiquitous, isoform CRA_c, partial [Mus musculus]" 17159 4326 15.35666667 14.13 -0.120103632 Down 0.26305051 Man2b1 "mannosidase 2, alpha B1" K12311|1|0.0|2022|mmu:17159|lysosomal alpha-mannosidase [EC:3.2.1.24] GO:0000323//lytic vacuole GO:0048029//monosaccharide binding;GO:0046914//transition metal ion binding;GO:0015923//mannosidase activity GO:0044708//single-organism behavior;GO:0036211//protein modification process;GO:0019318//hexose metabolic process gi|113195690|ref|NP_034894.2|/0/lysosomal alpha-mannosidase precursor [Mus musculus] 12960 881 1.553333333 1.223333333 -0.344549892 Down 0.26305051 Crybb1 "crystallin, beta B1" K16810|1|2e-16|89.0|bacu:103015945|TBCC domain-containing protein 1;K01886|2|4e-11|70.9|fpg:101924025|glutaminyl-tRNA synthetase [EC:6.1.1.18] - - - gi|568935248|ref|XP_006534817.1|/7.04859e-121/PREDICTED: beta-crystallin B1 isoform X4 [Mus musculus] 319150 461 0.01 0.123333333 3.624490865 Up 0.262984693 Hist1h3b "histone cluster 1, H3b" K11253|1|4e-71|268|cge:100757491|histone H3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization gi|831287812|ref|XP_012675282.1|/1.90437e-70/PREDICTED: histone H3-like centromeric protein CSE4 [Clupea harengus] 23900 452 0.12 0.01 -3.584962501 Down 0.262984693 Hcst hematopoietic cell signal transducer K07988|1|1e-34|147|mmu:23900|hematopoietic cell signal transducer GO:0031224//intrinsic component of membrane;GO:0044464 GO:0005515//protein binding GO:0009967//positive regulation of signal transduction gi|93102419|ref|NP_035957.2|/8.42052e-34/hematopoietic cell signal transducer precursor [Mus musculus] 12046 444 0.01 0.12 3.584962501 Up 0.262984693 Bcl2a1c B cell leukemia/lymphoma 2 related protein A1c K02162|1|3e-70|265|mmu:12046|hematopoietic Bcl-2-related protein A1 GO:0044424 GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0004869//cysteine-type endopeptidase inhibitor activity GO:0030098//lymphocyte differentiation;GO:0006915//apoptotic process;GO:0050851//antigen receptor-mediated signaling pathway gi|113679691|ref|NP_031561.2|/2.7848e-69/B cell leukemia/lymphoma 2 related protein A1c [Mus musculus] 16530 1146 0.01 0.12 3.584962501 Up 0.262984693 Kcnk7 "potassium channel, subfamily K, member 7" K04918|1|3e-145|516|mmu:16530|potassium channel subfamily K member 7 GO:0016021//integral component of membrane GO:0005261//cation channel activity GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|51944955|ref|NP_034739.2|/2.81184e-144/potassium channel subfamily K member 7 precursor [Mus musculus] 100042944 442 0.123333333 0.01 -3.624490865 Down 0.262984693 Gm14478 predicted gene 14478 K11251|1|8e-32|137|mmu:100042929|histone H2A GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0003676//nucleic acid binding GO:0044260;GO:0090304 gi|161333850|ref|NP_001104507.1|/6.72239e-31/histone cluster 2 family member [Mus musculus] 625286 3658 0.01 0.12 3.584962501 Up 0.262984693 Tmem236 transmembrane protein 236 "K06560|1|3e-09|67.4|bacu:103015292|mannose receptor, C type" GO:0031224//intrinsic component of membrane - - gi|124486799|ref|NP_001074779.1|/1.48282e-173/transmembrane protein 236 [Mus musculus] 217066 812 0.01 0.123333333 3.624490865 Up 0.262984693 Gm15698 "transcription elongation factor B (SIII), polypeptide 2 pseudogene" "K03873|1|5e-35|150|hgl:101715777|transcription elongation factor B, polypeptide 2" GO:0043231//intracellular membrane-bounded organelle;GO:0000153//cytoplasmic ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex "GO:0044389//ubiquitin-like protein ligase binding;GO:0008135//translation factor activity, RNA binding;GO:0019787//ubiquitin-like protein transferase activity" GO:0006412//translation;GO:0032446//protein modification by small protein conjugation;GO:0006366//transcription from RNA polymerase II promoter "gi|148683915|gb|EDL15862.1|/2.08695e-80/mCG55628, partial [Mus musculus]" 269683 931 0.12 0.01 -3.584962501 Down 0.262984693 E130006D01Rik RIKEN cDNA E130006D01 gene - - - - - 66107 452 0.12 0.01 -3.584962501 Down 0.262984693 Wfdc21 WAP four-disulfide core domain 21 - GO:0044421 GO:0008047//enzyme activator activity GO:0002237//response to molecule of bacterial origin;GO:0034097//response to cytokine;GO:0045444//fat cell differentiation;GO:0044093 gi|34304022|ref|NP_899072.1|/3.92056e-23/WDNM1-like protein precursor [Mus musculus] 71326 1241 0.01 0.12 3.584962501 Up 0.262984693 Treml1 triggering receptor expressed on myeloid cells-like 1 K14363|1|1e-141|505|mmu:71326|trem-like transcript 1 protein GO:0030141//secretory granule;GO:0016020//membrane;GO:0031224//intrinsic component of membrane;GO:0030141//secretory granule;GO:0031224//intrinsic component of membrane;GO:0030141//secretory granule;GO:0031224//intrinsic component of membrane;GO:0030141//secretory granule GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0009611//response to wounding;GO:0019932//second-messenger-mediated signaling;GO:0009611//response to wounding;GO:0019932//second-messenger-mediated signaling;GO:0009611//response to wounding;GO:0019932//second-messenger-mediated signaling;GO:0009611//response to wounding;GO:0019932//second-messenger-mediated signaling gi|575403017|ref|NP_001276380.1|/5.1188e-106/trem-like transcript 1 protein isoform 2 precursor [Mus musculus] 381059 781 0.01 0.12 3.584962501 Up 0.262984693 Gm1604b predicted gene 1604b - - - - gi|85701955|ref|NP_001028614.1|/1.55597e-13/uncharacterized protein LOC381059 [Mus musculus] 71321 1144 0.01 0.123333333 3.624490865 Up 0.262984693 4933440J02Rik RIKEN cDNA 4933440J02 gene - - - - - 21947 1250 0.01 0.123333333 3.624490865 Up 0.262984693 Cd40lg CD40 ligand K03161|1|6e-144|513|mmu:21947|tumor necrosis factor ligand superfamily member 5 - - - - 432649 1458 0.12 0.01 -3.584962501 Down 0.262984693 Gm5434 ubiquitin-conjugating enzyme E2F (putative) pseudogene K10687|1|5e-96|353|mmu:67921|ubiquitin-conjugating enzyme E2 F [EC:2.3.2.23] - GO:0019787//ubiquitin-like protein transferase activity;GO:0032550 GO:0032446//protein modification by small protein conjugation gi|148704907|gb|EDL36854.1|/9.26909e-109/mCG50154 [Mus musculus] 108115 3100 0.01 0.12 3.584962501 Up 0.262984693 Slco4a1 "solute carrier organic anion transporter family, member 4a1" "K14354|1|0.0|1311|mmu:108115|solute carrier organic anion transporter family, member 4A" GO:0016021//integral component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity GO:0006820//anion transport;GO:0009914//hormone transport;GO:0006575//cellular modified amino acid metabolic process gi|22507335|ref|NP_683735.1|/0/solute carrier organic anion transporter family member 4A1 [Mus musculus] 53404 450 0.01 0.123333333 3.624490865 Up 0.262984693 Atoh7 atonal bHLH transcription factor 7 K09083|1|3e-57|221|mmu:53404|atonal protein 1/7 - - - - 70055 985 0.01 0.12 3.584962501 Up 0.262984693 1700030L20Rik RIKEN cDNA 1700030L20 gene - - - - - 277353 2237 0.01 0.123333333 3.624490865 Up 0.262984693 Tcfl5 transcription factor-like 5 (basic helix-loop-helix) K09092|1|0.0|657|mmu:277353|transcription factor-like 5 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|225007623|ref|NP_839985.2|/0/transcription factor-like 5 protein [Mus musculus] 381350 1651 0.01 0.123333333 3.624490865 Up 0.262984693 Spag6l sperm associated antigen 6 K15043|1|1e-16|90.9|nve:NEMVE_v1g195115|importin subunit alpha-2 - - - - 194292 470 0.123333333 0.01 -3.624490865 Down 0.262984693 Gm5 predicted gene 5 - - - - - 100047133 858 0.123333333 0.01 -3.624490865 Down 0.262984693 Gm16894 "predicted gene, 16894" - - - - - 75058 968 0.01 0.12 3.584962501 Up 0.262984693 4930519H02Rik RIKEN cDNA 4930519H02 gene - - - - - 109215 894 0.123333333 0.01 -3.624490865 Down 0.262984693 Lncbate1 brown adipose tissue enriched long non-coding RNA 1 - - - - - 19069 2462.7 22.5 24.24 0.107464697 Up 0.262947083 Nup88 nucleoporin 88 K14318|1|0.0|1447|mmu:19069|nuclear pore complex protein Nup88 GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0031981//nuclear lumen;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0031981//nuclear lumen;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0031981//nuclear lumen;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0031981//nuclear lumen GO:0022829//wide pore channel activity;GO:0022829//wide pore channel activity;GO:0022829//wide pore channel activity;GO:0022829//wide pore channel activity GO:0050658//RNA transport;GO:0044763;GO:0045184//establishment of protein localization;GO:0050658//RNA transport;GO:0044763;GO:0045184//establishment of protein localization;GO:0050658//RNA transport;GO:0044763;GO:0045184//establishment of protein localization;GO:0050658//RNA transport;GO:0044763;GO:0045184//establishment of protein localization gi|111955409|ref|NP_765982.2|/0/nuclear pore complex protein Nup88 isoform 1 [Mus musculus] 14630 2072 10.73333333 11.72 0.126874382 Up 0.26285306 Gclm "glutamate-cysteine ligase, modifier subunit" K11205|1|4e-146|521|mmu:14630|glutamate--cysteine ligase regulatory subunit GO:0043234//protein complex GO:0016881//acid-amino acid ligase activity;GO:0019899//enzyme binding;GO:0046983//protein dimerization activity GO:0003254//regulation of membrane depolarization;GO:0009064//glutamine family amino acid metabolic process;GO:0006749//glutathione metabolic process;GO:0035227;GO:0000096//sulfur amino acid metabolic process;GO:0042221//response to chemical;GO:0003018;GO:0043066//negative regulation of apoptotic process;GO:0006950//response to stress gi|6680019|ref|NP_032155.1|/3.34346e-145/glutamate--cysteine ligase regulatory subunit [Mus musculus] 232807 2982 41.07333333 44.15333333 0.104320323 Up 0.262824852 Ppp1r12c "protein phosphatase 1, regulatory (inhibitor) subunit 12C" K17457|1|0.0|1186|mmu:232807|protein phosphatase 1 regulatory subunit 12C GO:0044424 GO:0005488//binding - gi|124249341|ref|NP_084110.2|/0/protein phosphatase 1 regulatory subunit 12C [Mus musculus] 20851 4927.28 23.41333333 21.68333333 -0.110743788 Down 0.26281545 Stat5b signal transducer and activator of transcription 5B K11224|1|0.0|1558|mmu:20851|signal transducer and activator of transcription 5B GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0060089;GO:0035258//steroid hormone receptor binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0043566//structure-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding GO:0001779//natural killer cell differentiation;GO:0072350//tricarboxylic acid metabolic process;GO:0006915//apoptotic process;GO:0010876//lipid localization;GO:0043648//dicarboxylic acid metabolic process;GO:0002260//lymphocyte homeostasis;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0042094//interleukin-2 biosynthetic process;GO:0032787//monocarboxylic acid metabolic process;GO:0035264//multicellular organism growth;GO:0007259//JAK-STAT cascade;GO:0008207//C21-steroid hormone metabolic process;GO:0007589//body fluid secretion;GO:0072338;GO:0002526//acute inflammatory response;GO:0009081//branched-chain amino acid metabolic process;GO:0006790//sulfur compound metabolic process;GO:0000278//mitotic cell cycle;GO:0042492//gamma-delta T cell differentiation;GO:0001787//natural killer cell proliferation;GO:0002237//response to molecule of bacterial origin;GO:0043627//response to estrogen;GO:0030183//B cell differentiation;GO:0007166//cell surface receptor signaling pathway;GO:0045136//development of secondary sexual characteristics;GO:0044703;GO:0006366//transcription from RNA polymerase II promoter;GO:0007155//cell adhesion;GO:0030855//epithelial cell differentiation;GO:0008585//female gonad development;GO:0006928//movement of cell or subcellular component;GO:0030218//erythrocyte differentiation;GO:0034097//response to cytokine;GO:0097305//response to alcohol;GO:0048537//mucosal-associated lymphoid tissue development;GO:0006575//cellular modified amino acid metabolic process;GO:0042102//positive regulation of T cell proliferation gi|165932366|ref|NP_035619.3|/0/signal transducer and activator of transcription 5B [Mus musculus] 14651 1180.93 46.51333333 43.44666667 -0.098398839 Down 0.262759036 Hagh hydroxyacyl glutathione hydrolase K01069|1|3e-150|533|mmu:14651|hydroxyacylglutathione hydrolase [EC:3.1.2.6] GO:0044429;GO:0044429 GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding;GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding GO:0006749//glutathione metabolic process;GO:0048232//male gamete generation;GO:0006749//glutathione metabolic process;GO:0048232//male gamete generation "gi|227499238|ref|NP_077246.2|/2.37222e-149/hydroxyacylglutathione hydrolase, mitochondrial isoform 1 precursor [Mus musculus]" 319655 2017 6.873333333 7.613333333 0.147518318 Up 0.262740231 Podxl2 podocalyxin-like 2 K06818|1|0.0|931|mmu:319655|podocalyxin-like 2 GO:0031224//intrinsic component of membrane - GO:0007159//leukocyte cell-cell adhesion gi|568942122|ref|XP_006506309.1|/0/PREDICTED: podocalyxin-like protein 2 isoform X3 [Mus musculus] 70461 5110 7.56 6.82 -0.148614495 Down 0.262740231 Crtc3 CREB regulated transcription coactivator 3 K16334|1|0.0|1096|mmu:70461|CREB-regulated transcription coactivator 3 - - - - 108989 7550 15.44 14.22333333 -0.118413143 Down 0.262693219 Tpr "translocated promoter region, nuclear basket protein" K09291|1|0.0|3638|mmu:108989|nucleoprotein TPR "GO:0031981//nuclear lumen;GO:0005643//nuclear pore;GO:0030286//dynein complex;GO:0005819//spindle;GO:0016234//inclusion body;GO:0000775//chromosome, centromeric region" GO:0005215//transporter activity;GO:0032403//protein complex binding;GO:0042802//identical protein binding;GO:0008092//cytoskeletal protein binding;GO:0003723//RNA binding;GO:0019901//protein kinase binding GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0006406//mRNA export from nucleus;GO:0032388//positive regulation of intracellular transport;GO:0031445//regulation of heterochromatin assembly;GO:0090232//positive regulation of spindle checkpoint;GO:0033047//regulation of mitotic sister chromatid segregation;GO:0006413//translational initiation;GO:0006997//nucleus organization;GO:0009408//response to heat;GO:0006606//protein import into nucleus;GO:0000165//MAPK cascade;GO:0009719 gi|270309140|ref|NP_598541.3|/0/nucleoprotein TPR [Mus musculus] 22129 7295 8.343333333 9.183333333 0.138394028 Up 0.262674414 Ttc3 tetratricopeptide repeat domain 3 K15712|1|0.0|3578|mmu:22129|E3 ubiquitin-protein ligase TTC3 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0000209//protein polyubiquitination;GO:0019941//modification-dependent protein catabolic process;GO:0030182//neuron differentiation;GO:0000904//cell morphogenesis involved in differentiation gi|568997436|ref|XP_006523047.1|/0/PREDICTED: E3 ubiquitin-protein ligase TTC3 isoform X2 [Mus musculus] 12395 7324 0.443333333 0.683333333 0.624197664 Up 0.262646207 Runx1t1 "runt-related transcription factor 1; translocated to, 1 (cyclin D-related)" "K10053|1|0.0|996|myb:102243741|runt-related transcription factor 1; translocated to, 1" GO:0034399//nuclear periphery;GO:0034399//nuclear periphery;GO:0034399//nuclear periphery GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0051098//regulation of binding;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0051098//regulation of binding;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0051098//regulation of binding" gi|554543965|ref|XP_005866583.1|/0/PREDICTED: protein CBFA2T1 isoform X1 [Myotis brandtii] 194388 10907 1.826666667 1.476666667 -0.306869194 Down 0.262636805 Tet3 tet methylcytosine dioxygenase 3 K13097|1|0.0|690|lcm:102366582|methylcytosine dioxygenase [EC:1.14.11.-] - "GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" - "gi|148666664|gb|EDK99080.1|/0/mCG133587, partial [Mus musculus]" 20319 2001 1.823333333 1.473333333 -0.307494463 Down 0.262636805 Sfrp2 secreted frizzled-related protein 2 K02176|1|2e-165|585|mmu:20319|secreted frizzled-related protein 2 GO:0044421 GO:0005102//receptor binding;GO:0061135;GO:0008047//enzyme activator activity GO:0030326//embryonic limb morphogenesis;GO:0014020;GO:0030177//positive regulation of Wnt signaling pathway;GO:0010165//response to X-ray;GO:0007501//mesodermal cell fate specification;GO:0008406//gonad development;GO:0009952//anterior/posterior pattern specification;GO:0035411//catenin import into nucleus;GO:2000040//regulation of planar cell polarity pathway involved in axis elongation;GO:0002062//chondrocyte differentiation;GO:0016049//cell growth;GO:0001837//epithelial to mesenchymal transition;GO:0016477//cell migration;GO:0010952//positive regulation of peptidase activity;GO:0045992//negative regulation of embryonic development;GO:0001934//positive regulation of protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0045444//fat cell differentiation;GO:0001649//osteoblast differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0043407//negative regulation of MAP kinase activity;GO:0042221//response to chemical;GO:0051302//regulation of cell division;GO:0030198//extracellular matrix organization;GO:0008285//negative regulation of cell proliferation;GO:0001525//angiogenesis;GO:0010659//cardiac muscle cell apoptotic process;GO:0003208//cardiac ventricle morphogenesis gi|635045300|ref|XP_007998238.1|/1.24774e-165/PREDICTED: secreted frizzled-related protein 2 [Chlorocebus sabaeus] 100342 2288 1.383333333 1.723333333 0.317052944 Up 0.262608598 Fam46b "family with sequence similarity 46, member B" "K05742|1|4e-124|448|apla:101803574|solute carrier family 9 (sodium/hydrogen exchanger), member 1" - - - gi|30424982|ref|NP_780516.1|/0/protein FAM46B [Mus musculus] 268706 8913 1.376666667 1.72 0.321229284 Up 0.262608598 Slc38a9 "solute carrier family 38, member 9" "K14995|1|0.0|1042|mmu:268706|solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 9" - - - - 100038494 1480 0.136666667 0.313333333 1.197036847 Up 0.262589793 Gm10782 predicted gene 10782 - - - - "gi|148709290|gb|EDL41236.1|/1.17879e-50/mCG1044050, partial [Mus musculus]" 76138 2466 0.22 0.063333333 -1.796466606 Down 0.262495769 Ccdc138 coiled-coil domain containing 138 K11167|1|4e-15|86.3|cjo:107321965|dehydrogenase/reductase SDR family member 7C [EC:1.1.-.-];K20478|2|9e-07|58.5|hmg:100201149|golgin subfamily B member 1;K10421|3|7e-06|55.5|dgr:Dgri_GH11701|CAP-Gly domain-containing linker protein 1 - - - gi|242397425|ref|NP_001156428.1|/0/coiled-coil domain-containing protein 138 [Mus musculus] 231889 881.04 40.09 43.10666667 0.104668589 Up 0.262476964 Bud31 BUD31 homolog K12873|1|2e-84|314|shr:100925071|bud site selection protein 31 - - - - 16803 2528 4.756666667 5.366666667 0.174075354 Up 0.262458159 Lbp lipopolysaccharide binding protein K05399|1|0.0|917|mmu:16803|lipopolysaccharide-binding protein GO:0044421 GO:0005515//protein binding;GO:0008289//lipid binding GO:0032496//response to lipopolysaccharide;GO:0007166//cell surface receptor signaling pathway;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0002526//acute inflammatory response;GO:0070391;GO:0006869//lipid transport;GO:0001818//negative regulation of cytokine production;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0002523//leukocyte migration involved in inflammatory response;GO:0042742//defense response to bacterium;GO:0001819//positive regulation of cytokine production;GO:0002696//positive regulation of leukocyte activation;GO:0002536//respiratory burst involved in inflammatory response;GO:0002275//myeloid cell activation involved in immune response;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0044126 gi|113865991|ref|NP_032515.2|/0/lipopolysaccharide-binding protein precursor [Mus musculus] 22619 3433 4.773333333 5.38 0.172609086 Up 0.262458159 Siae sialic acid acetylesterase K05970|1|0.0|1099|mmu:22619|sialate O-acetylesterase [EC:3.1.1.53] GO:0000323//lytic vacuole GO:0052689//carboxylic ester hydrolase activity - gi|31560532|ref|NP_035864.2|/0/sialate O-acetylesterase precursor [Mus musculus] 68817 3539 4.833333333 5.443333333 0.171471891 Up 0.262458159 Ddi2 DNA-damage inducible protein 2 K11885|1|0.0|726|ngi:103725332|DNA damage-inducible protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0016020//membrane - "GO:0006810//transport;GO:0006351//transcription, DNA-templated;GO:0022600//digestive system process" gi|77404400|ref|NP_076033.4|/0/regulatory solute carrier protein family 1 member 1 [Mus musculus] 71474 3476.76 23.82333333 22.11 -0.107676262 Down 0.262448757 Ppp6r2 "protein phosphatase 6, regulatory subunit 2" K15500|1|6e-115|417|mmu:71474|serine/threonine-protein phosphatase 6 regulatory subunit 2 GO:0043227//membrane-bounded organelle;GO:0044424;GO:0043227//membrane-bounded organelle;GO:0044424 - - gi|54145496|ref|NP_081089.1|/0/serine/threonine-protein phosphatase 6 regulatory subunit 2 isoform 1 [Mus musculus] 17425 7462 6.283333333 5.61 -0.163529347 Down 0.262439355 Foxk1 forkhead box K1 K09404|1|0.0|1056|mmu:17425|forkhead box protein K GO:0031981//nuclear lumen GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0048513//animal organ development;GO:0048869//cellular developmental process;GO:0050794//regulation of cellular process;GO:0016049//cell growth" gi|82546826|ref|NP_951031.2|/0/forkhead box protein K1 [Mus musculus] 52626 1880 5.583333333 6.25 0.1627295 Up 0.262439355 Cdkn2aipnl CDKN2A interacting protein N-terminal like - - - - "gi|148701690|gb|EDL33637.1|/6.12282e-58/DNA segment, Chr 11, ERATO Doi 497, expressed, isoform CRA_b, partial [Mus musculus]" 233833 8493 5.63 6.296666667 0.161453374 Up 0.262439355 Tnrc6a trinucleotide repeat containing 6a K18412|1|0.0|3262|mmu:233833|trinucleotide repeat-containing gene 6 protein - - - gi|123791339|sp|Q3UHK8.1|TNR6A_MOUSE/0/RecName: Full=Trinucleotide repeat-containing gene 6A protein 100504202 2095 0.07 0.233333333 1.736965594 Up 0.262354733 Gm20110 "predicted gene, 20110" - - - - - 434794 1191 0.223333333 0.066666667 -1.744161096 Down 0.262354733 Xlr4a X-linked lymphocyte-regulated 4A K19528|1|4e-14|81.6|aam:106488650|synaptonemal complex protein 3 - - - gi|126032323|ref|NP_001075111.1|/1.65272e-102/X-linked lymphocyte-regulated 4A [Mus musculus] 66592 1565 41.46666667 44.45333333 0.100339524 Up 0.262335928 Stoml2 stomatin (Epb7.2)-like 2 "K03364|1|1e-89|332|dse:Dsec_GM16067|cell division cycle 20-like protein 1, cofactor of APC complex;K17286|3|4e-26|122|dre:550523|erythrocyte band 7 integral membrane protein" GO:0005856//cytoskeleton;GO:0043235//receptor complex;GO:0019898//extrinsic component of membrane;GO:0005740//mitochondrial envelope;GO:0019866//organelle inner membrane;GO:0044459 GO:1901611//phosphatidylglycerol binding GO:0033036;GO:0006461//protein complex assembly;GO:0006816//calcium ion transport;GO:0045838//positive regulation of membrane potential;GO:0050851//antigen receptor-mediated signaling pathway;GO:0046631//alpha-beta T cell activation;GO:0001816//cytokine production;GO:0016485//protein processing;GO:0008053//mitochondrial fusion;GO:0090296//regulation of mitochondrial DNA replication;GO:0006839//mitochondrial transport;GO:0045834//positive regulation of lipid metabolic process;GO:0006875//cellular metal ion homeostasis "gi|12963591|ref|NP_075720.1|/1.26638e-167/stomatin-like protein 2, mitochondrial [Mus musculus]" 231871 3257 4.343333333 4.916666667 0.178877871 Up 0.262317124 Daglb "diacylglycerol lipase, beta" K13806|1|0.0|1233|mmu:231871|sn1-specific diacylglycerol lipase [EC:3.1.1.-] - - - gi|31559956|ref|NP_659164.2|/0/sn1-specific diacylglycerol lipase beta [Mus musculus] 59025 4185 15.42666667 14.21666667 -0.117843123 Down 0.262288916 Usp14 ubiquitin specific peptidase 14 K11843|1|0.0|932|mmu:59025|ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane "GO:0016790//thiolester hydrolase activity;GO:0004175//endopeptidase activity;GO:0061135;GO:0008192//RNA guanylyltransferase activity;GO:0032403//protein complex binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016790//thiolester hydrolase activity;GO:0061135;GO:0032403//protein complex binding" GO:0010498//proteasomal protein catabolic process;GO:0007267//cell-cell signaling;GO:0019941//modification-dependent protein catabolic process;GO:0006935//chemotaxis;GO:0010466//negative regulation of peptidase activity;GO:0010498//proteasomal protein catabolic process;GO:0007267//cell-cell signaling;GO:0019941//modification-dependent protein catabolic process;GO:0006935//chemotaxis;GO:0010466//negative regulation of peptidase activity "gi|148691054|gb|EDL23001.1|/0/ubiquitin specific peptidase 14, isoform CRA_a, partial [Mus musculus]" 30058 1243 15.46 14.25333333 -0.117240967 Down 0.262288916 Timm8a1 translocase of inner mitochondrial membrane 8A1 K17780|1|2e-44|182|mmu:30058|mitochondrial import inner membrane translocase subunit TIM8 - - - - 24100 1829 21.23 22.92 0.110502673 Up 0.262119674 Tpra1 "transmembrane protein, adipocyte asscociated 1" "K17564|1|2e-06|56.6|acs:100560175|coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial" GO:0031224//intrinsic component of membrane - - gi|564347770|ref|XP_006236928.1|/0/PREDICTED: transmembrane protein adipocyte-associated 1 isoform X2 [Rattus norvegicus] 107885 768 2.73 3.176666667 0.218612762 Up 0.262110271 Mthfs "5, 10-methenyltetrahydrofolate synthetase" K01934|1|1e-104|381|mmu:107885|5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0032550;GO:0016882//cyclo-ligase activity GO:0006915//apoptotic process;GO:0006760//folic acid-containing compound metabolic process gi|18093092|ref|NP_081105.1|/9.10789e-104/5-formyltetrahydrofolate cyclo-ligase [Mus musculus] 237823 6369 2.753333333 3.2 0.216892624 Up 0.262110271 Pfas phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) K01952|1|0.0|2607|mmu:237823|phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] GO:0044444//cytoplasmic part "GO:0032550;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor" GO:0006188//IMP biosynthetic process;GO:0009064//glutamine family amino acid metabolic process;GO:0042221//response to chemical;GO:0009112 gi|226958458|ref|NP_001152991.1|/0/phosphoribosylformylglycinamidine synthase [Mus musculus] 231549 3944 2.773333333 3.226666667 0.218423519 Up 0.262110271 Lrrc8d leucine rich repeat containing 8D K19613|1|7e-31|139|bfo:BRAFLDRAFT_214464|leucine-rich repeat protein SHOC2 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|170650655|ref|NP_848816.3|/0/volume-regulated anion channel subunit LRRC8D [Mus musculus] 83962 3020 42.83333333 39.88 -0.103068544 Down 0.262091466 Btbd1 BTB (POZ) domain containing 1 K10477|1|0.0|863|mmu:83962|BTB/POZ domain-containing protein 1/2 GO:0035770//ribonucleoprotein granule GO:0005488//binding GO:0051098//regulation of binding;GO:0032446//protein modification by small protein conjugation "gi|148674971|gb|EDL06918.1|/0/BTB (POZ) domain containing 1, partial [Mus musculus]" 216439 5585 7.473333333 6.743333333 -0.148289958 Down 0.262053857 Agap2 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 2" "K17848|1|0.0|1414|mmu:216439|Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2" GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0008289//lipid binding;GO:0019900//kinase binding;GO:0008047//enzyme activator activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0019887//protein kinase regulator activity;GO:0046914//transition metal ion binding;GO:0046872//metal ion binding;GO:0019900//kinase binding;GO:0008047//enzyme activator activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0019887//protein kinase regulator activity GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0007010//cytoskeleton organization;GO:0032012//regulation of ARF protein signal transduction;GO:0007259//JAK-STAT cascade;GO:0009895;GO:0001934//positive regulation of protein phosphorylation;GO:0006935//chemotaxis;GO:0006366//transcription from RNA polymerase II promoter;GO:0044765//single-organism transport;GO:0033598//mammary gland epithelial cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0007010//cytoskeleton organization;GO:0009966//regulation of signal transduction;GO:0007259//JAK-STAT cascade;GO:0009895;GO:0001934//positive regulation of protein phosphorylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0044765//single-organism transport;GO:0033598//mammary gland epithelial cell proliferation;GO:0043066//negative regulation of apoptotic process "gi|84370300|ref|NP_001028435.1|/0/arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform 1 [Mus musculus]" 237500 5990 1.06 1.366666667 0.366597144 Up 0.26202565 Tmtc3 transmembrane and tetratricopeptide repeat containing 3 K09667|1|6e-18|95.9|crg:105329715|protein O-GlcNAc transferase [EC:2.4.1.255] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0055002//striated muscle cell development;GO:0010467//gene expression;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0055002//striated muscle cell development;GO:0010467//gene expression gi|158517929|ref|NP_001103483.1|/0/transmembrane and TPR repeat-containing protein 3 isoform 1 [Mus musculus] 26356 2089.28 8.263333333 9.093333333 0.138085373 Up 0.262006845 Ing1 "inhibitor of growth family, member 1" K19197|1|1e-132|476|mmu:26356|inhibitor of growth protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0042393//histone binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0046914//transition metal ion binding "GO:0008219//cell death;GO:0006351//transcription, DNA-templated;GO:0006886//intracellular protein transport;GO:0008219//cell death;GO:0006351//transcription, DNA-templated;GO:0006886//intracellular protein transport;GO:0008219//cell death;GO:0006351//transcription, DNA-templated;GO:0006886//intracellular protein transport;GO:0008219//cell death;GO:0006351//transcription, DNA-templated;GO:0006886//intracellular protein transport;GO:0008219//cell death;GO:0006351//transcription, DNA-templated;GO:0006886//intracellular protein transport;GO:0008219//cell death;GO:0006351//transcription, DNA-templated;GO:0006886//intracellular protein transport" "gi|148690124|gb|EDL22071.1|/9.2957e-105/mCG11176, partial [Mus musculus]" 68229 2350.92 8.356666667 9.183333333 0.136090323 Up 0.262006845 AI846148 expressed sequence AI846148 - - - - "gi|148701354|gb|EDL33301.1|/1.82635e-180/mCG14919, isoform CRA_a, partial [Mus musculus]" 75429 558 0.863333333 0.606666667 -0.509013647 Down 0.261978638 Fam183b "family with sequence similarity 183, member B" - - - - gi|242247217|ref|NP_001156350.1|/7.15793e-64/protein FAM183B isoform 2 [Mus musculus] 108147 2611 14.28 15.48 0.116409492 Up 0.261931626 Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase K00602|1|0.0|1129|mmu:108147|phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] GO:0043231//intracellular membrane-bounded organelle "GO:0016742//hydroxymethyl-, formyl- and related transferase activity;GO:0042802//identical protein binding;GO:0019238//cyclohydrolase activity" GO:0022037//metencephalon development;GO:0021543//pallium development;GO:0006188//IMP biosynthetic process;GO:0009396//folic acid-containing compound biosynthetic process;GO:0009887//organ morphogenesis;GO:0042221//response to chemical;GO:0006767//water-soluble vitamin metabolic process gi|227908823|ref|NP_080471.2|/0/bifunctional purine biosynthesis protein PURH [Mus musculus] 18671 4977 3.933333333 3.43 -0.197543877 Down 0.261903419 Abcb1a "ATP-binding cassette, sub-family B (MDR/TAP), member 1A" "K05658|1|0.0|2296|mmu:18671|ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:3.6.3.44]" - - - gi|153791547|ref|NP_035206.2|/0/multidrug resistance protein 1A [Mus musculus] 449521 2686 3.316666667 3.816666667 0.202579168 Up 0.261903419 Zfp213 zinc finger protein 213 K09229|1|0.0|941|mmu:449521|KRAB and SCAN domains-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding "GO:0006351//transcription, DNA-templated" gi|255003788|ref|NP_001028668.2|/0/zinc finger protein 213 [Mus musculus] 244721 2755 0.96 1.256666667 0.388495712 Up 0.261884614 Zfp846 zinc finger protein 846 K09228|1|0.0|1105|ngi:103734319|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|117938303|ref|NP_766507.2|/0/zinc finger protein 846 [Mus musculus] 20348 4956 1.28 0.98 -0.385290156 Down 0.261884614 Sema3c "sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C" K06840|1|0.0|1545|mmu:20348|semaphorin 3 GO:0044421 GO:0005102//receptor binding GO:0048869//cellular developmental process;GO:0060445//branching involved in salivary gland morphogenesis;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0048771//tissue remodeling;GO:0001667//ameboidal-type cell migration;GO:0006935//chemotaxis;GO:0007399//nervous system development;GO:0003208//cardiac ventricle morphogenesis;GO:0014706//striated muscle tissue development gi|672048614|ref|XP_008760868.1|/0/PREDICTED: semaphorin-3C isoform X2 [Rattus norvegicus] 78914 2481 1.87 2.253333333 0.269022476 Up 0.261837602 Nadsyn1 NAD synthetase 1 K01950|1|0.0|1018|mmu:78914|NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1] - "GO:0032550;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0016787//hydrolase activity;GO:0032550;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0016787//hydrolase activity" GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0019359//nicotinamide nucleotide biosynthetic process gi|21313534|ref|NP_084497.1|/0/glutamine-dependent NAD(+) synthetase isoform 1 [Mus musculus] 20832 808.48 41.33666667 44.22 0.097276969 Up 0.26179059 Ssr4 "signal sequence receptor, delta" K04571|1|5e-90|332|ngi:103731199|translocon-associated protein subunit delta GO:0071256;GO:0031224//intrinsic component of membrane;GO:0071256;GO:0031224//intrinsic component of membrane - - gi|674043683|ref|XP_008827766.1|/3.13584e-100/PREDICTED: translocon-associated protein subunit delta isoform X1 [Nannospalax galili] 18970 1227 21.33333333 23.00333333 0.108733528 Up 0.261762383 Polb "polymerase (DNA directed), beta" K02330|1|0.0|672|mmu:18970|DNA polymerase beta [EC:2.7.7.7 4.2.99.-] GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle GO:0043169//cation binding;GO:0003677//DNA binding;GO:0034061//DNA polymerase activity;GO:0015631//tubulin binding GO:0006281//DNA repair;GO:0097305//response to alcohol;GO:0006915//apoptotic process gi|21729749|ref|NP_035260.1|/0/DNA polymerase beta [Mus musculus] 217666 3338 10.17666667 11.15 0.131778621 Up 0.261752981 L2hgdh L-2-hydroxyglutarate dehydrogenase K00109|1|0.0|890|mmu:217666|2-hydroxyglutarate dehydrogenase [EC:1.1.99.2] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle "GO:0016614//oxidoreductase activity, acting on CH-OH group of donors" GO:0044710;GO:0019538//protein metabolic process "gi|148704655|gb|EDL36602.1|/0/L-2-hydroxyglutarate dehydrogenase, partial [Mus musculus]" 214489 3046 10.67 11.64333333 0.125943966 Up 0.261752981 BC003965 cDNA sequence BC003965 - - - - - 66427 4294 13.51333333 14.70333333 0.121759672 Up 0.261677761 Cyb5b cytochrome b5 type B K19703|1|1e-11|75.9|tad:TRIADDRAFT_37592|4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase [EC:1.14.18.6];K00326|2|1e-11|75.5|cin:100178699|cytochrome-b5 reductase [EC:1.6.2.2];K10595|3|5e-11|73.6|tad:TRIADDRAFT_56425|E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26];K10226|5|4e-10|70.5|aqu:100632154|acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3] GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane GO:0046906//tetrapyrrole binding;GO:0043169//cation binding;GO:0009055//electron carrier activity;GO:0030234//enzyme regulator activity GO:0051234//establishment of localization;GO:0044093;GO:0006091//generation of precursor metabolites and energy gi|31542438|ref|NP_079834.2|/5.12184e-80/cytochrome b5 type B precursor [Mus musculus] 268709 3144 22.59333333 20.93 -0.110324825 Down 0.261621347 Fam107a "family with sequence similarity 107, member A" - GO:0043231//intracellular membrane-bounded organelle - GO:0016049//cell growth "gi|148688642|gb|EDL20589.1|/2.06082e-59/cDNA sequence BC055107, isoform CRA_a, partial [Mus musculus]" 68758 1199.66 41.46666667 38.62666667 -0.102354896 Down 0.261536726 Abhd11 abhydrolase domain containing 11 K13703|1|3e-131|471|mmu:68758|abhydrolase domain-containing protein 11 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity - gi|21644577|ref|NP_660250.1|/9.77161e-162/protein ABHD11 isoform 1 [Mus musculus] 219189 6842.15 39.12333333 41.96 0.100985384 Up 0.261536726 Vwa8 von Willebrand factor A domain containing 8 K14572|1|1e-15|88.6|ngi:103751152|midasin - - - gi|226958579|ref|NP_082182.1|/0/von Willebrand factor A domain-containing protein 8 isoform 1 precursor [Mus musculus] 330796 2874 0.26 0.47 0.854149134 Up 0.261508519 Gm38415 "predicted gene, 38415" - - - - - 77358 572 0.536666667 0.32 -0.745954377 Down 0.261480311 9430069I07Rik RIKEN cDNA 9430069I07 gene - - - - gi|371872723|ref|NP_001243090.1|/7.59965e-59/uncharacterized protein LOC77358 [Mus musculus] 69726 3769 1.6 1.96 0.292781749 Up 0.261442702 Smyd3 SET and MYND domain containing 3 K11426|1|0.0|855|mmu:69726|SET and MYND domain-containing protein - - - - 68149 2813 1.616666667 1.976666667 0.290047357 Up 0.261442702 Otub2 "OTU domain, ubiquitin aldehyde binding 2" K09603|1|1e-129|467|mmu:68149|ubiquitin thioesterase protein OTUB2 [EC:3.4.19.12] - GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity;GO:0008238//exopeptidase activity GO:0016579//protein deubiquitination;GO:0019752//carboxylic acid metabolic process;GO:0016579//protein deubiquitination;GO:0019752//carboxylic acid metabolic process;GO:0016579//protein deubiquitination;GO:0019752//carboxylic acid metabolic process "gi|148686890|gb|EDL18837.1|/0/OTU domain, ubiquitin aldehyde binding 2, isoform CRA_b, partial [Mus musculus]" 80707 2251 2.12 2.523333333 0.251266535 Up 0.261329873 Wwox WW domain-containing oxidoreductase K19329|1|0.0|848|mmu:80707|WW domain-containing oxidoreductase GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0044444//cytoplasmic part GO:0048037//cofactor binding;GO:0005515//protein binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0036094//small molecule binding;GO:0003824//catalytic activity GO:0001501//skeletal system development;GO:0071363//cellular response to growth factor stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0006915//apoptotic process;GO:0001503//ossification;GO:0006629//lipid metabolic process;GO:0012502//induction of programmed cell death gi|31980962|ref|NP_062519.2|/0/WW domain-containing oxidoreductase [Mus musculus] 108058 5587 23.36333333 21.71 -0.105886398 Down 0.261320471 Camk2d "calcium/calmodulin-dependent protein kinase II, delta" K04515|1|0.0|1048|fca:101098221|calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] GO:0030139//endocytic vesicle;GO:0033267;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0042383//sarcolemma;GO:0045202//synapse;GO:0044297//cell body;GO:0005789//endoplasmic reticulum membrane;GO:0044291//cell-cell contact zone;GO:0030139//endocytic vesicle;GO:0033267;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0042383//sarcolemma;GO:0045202//synapse;GO:0044297//cell body;GO:0005789//endoplasmic reticulum membrane;GO:0044291//cell-cell contact zone;GO:0044291//cell-cell contact zone;GO:0044297//cell body;GO:0005789//endoplasmic reticulum membrane;GO:0042383//sarcolemma;GO:0033267;GO:0045202//synapse GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0019899//enzyme binding;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0019899//enzyme binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0032550;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0044057;GO:0008284//positive regulation of cell proliferation;GO:0006814//sodium ion transport;GO:1901019//regulation of calcium ion transmembrane transporter activity;GO:0016049//cell growth;GO:0043410//positive regulation of MAPK cascade;GO:0019221//cytokine-mediated signaling pathway;GO:0003301//physiological cardiac muscle hypertrophy;GO:0016601//Rac protein signal transduction;GO:0006941//striated muscle contraction;GO:0007267//cell-cell signaling;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0000086//G2/M transition of mitotic cell cycle;GO:0014909//smooth muscle cell migration;GO:0006950//response to stress;GO:0006468//protein phosphorylation;GO:0044057;GO:0008284//positive regulation of cell proliferation;GO:0006814//sodium ion transport;GO:1901019//regulation of calcium ion transmembrane transporter activity;GO:0016049//cell growth;GO:0043410//positive regulation of MAPK cascade;GO:0019221//cytokine-mediated signaling pathway;GO:0003301//physiological cardiac muscle hypertrophy;GO:0016601//Rac protein signal transduction;GO:0006941//striated muscle contraction;GO:0007267//cell-cell signaling;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0000086//G2/M transition of mitotic cell cycle;GO:0014909//smooth muscle cell migration;GO:0006950//response to stress;GO:0006468//protein phosphorylation;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006941//striated muscle contraction;GO:0032879//regulation of localization;GO:0044772//mitotic cell cycle phase transition;GO:0003300//cardiac muscle hypertrophy;GO:0006468//protein phosphorylation;GO:0070838//divalent metal ion transport;GO:0006814//sodium ion transport gi|60360170|dbj|BAD90304.1|/0/mKIAA4163 protein [Mus musculus] 74533 4152 9.196666667 8.373333333 -0.135308992 Down 0.261320471 Gzf1 GDNF-inducible zinc finger protein 1 K09228|1|4e-76|289|obi:106868863|KRAB domain-containing zinc finger protein GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0003677//DNA binding GO:0048754//branching morphogenesis of an epithelial tube;GO:0006366//transcription from RNA polymerase II promoter gi|37674207|ref|NP_083262.1|/0/GDNF-inducible zinc finger protein 1 [Mus musculus] 68278 1659 8.083333333 8.903333333 0.139395229 Up 0.261320471 Ddx39 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 K13182|1|0.0|819|umr:103682110|ATP-dependent RNA helicase DDX39 [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle "GO:0032550;GO:0042623//ATPase activity, coupled" GO:0000377;GO:0006405//RNA export from nucleus gi|355703230|gb|EHH29721.1|/0/ATP-dependent RNA helicase DDX39 [Macaca mulatta] 69629 642 8.29 9.113333333 0.136606735 Up 0.261320471 2310039L15Rik RIKEN cDNA 2310039L15 gene - - - - - 18140 3583 1.066666667 0.786666667 -0.439285046 Down 0.261311068 Uhrf1 "ubiquitin-like, containing PHD and RING finger domains, 1" K10638|1|0.0|1539|mmu:18140|E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27] GO:0000785//chromatin;GO:0034399//nuclear periphery;GO:0000785//chromatin;GO:0034399//nuclear periphery;GO:0000785//chromatin;GO:0034399//nuclear periphery;GO:0000785//chromatin;GO:0034399//nuclear periphery GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0000166//nucleotide binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003690//double-stranded DNA binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0000166//nucleotide binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003690//double-stranded DNA binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0000166//nucleotide binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003690//double-stranded DNA binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0000166//nucleotide binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003690//double-stranded DNA binding GO:0031325//positive regulation of cellular metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006513//protein monoubiquitination;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006325//chromatin organization;GO:0031325//positive regulation of cellular metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006513//protein monoubiquitination;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006325//chromatin organization;GO:0031325//positive regulation of cellular metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006513//protein monoubiquitination;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006325//chromatin organization;GO:0031325//positive regulation of cellular metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006513//protein monoubiquitination;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006325//chromatin organization gi|74208423|dbj|BAE26398.1|/0/unnamed protein product [Mus musculus] 14825 964 0.47 0.713333333 0.601915634 Up 0.261273459 Cxcl1 chemokine (C-X-C motif) ligand 1 K05505|1|3e-35|151|mmu:14825|C-X-C motif chemokine 1/2/3 GO:0044421 GO:0005125//cytokine activity GO:0006954//inflammatory response;GO:0010212//response to ionizing radiation;GO:0043627//response to estrogen;GO:0006813//potassium ion transport;GO:0002028//regulation of sodium ion transport;GO:0031960//response to corticosteroid;GO:0002237//response to molecule of bacterial origin;GO:0030595//leukocyte chemotaxis;GO:0051480//regulation of cytosolic calcium ion concentration "gi|54887349|gb|AAH37997.1|/5.96739e-38/Cxcl1 protein, partial [Mus musculus]" 74629 1504 0.076666667 0.24 1.646363045 Up 0.261264057 4930426L09Rik RIKEN cDNA 4930426L09 gene - - - - gi|12853453|dbj|BAB29746.1|/7.51875e-69/unnamed protein product [Mus musculus] 234847 2558 40.14333333 37.36333333 -0.103537248 Down 0.261217045 Spg7 spastic paraplegia 7 homolog (human) K09552|1|0.0|1303|mmu:234847|spastic paraplegia 7 [EC:3.4.24.-] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0016462//pyrophosphatase activity GO:0006996//organelle organization;GO:0008088//axo-dendritic transport;GO:0019538//protein metabolic process;GO:0007155//cell adhesion;GO:0009057//macromolecule catabolic process "gi|148679760|gb|EDL11707.1|/0/mCG132921, isoform CRA_b, partial [Mus musculus]" 100294583 1507 0.386666667 0.616666667 0.673400465 Up 0.261151228 Fam150b "family with sequence similarity 150, member B" - - - - "gi|28204858|gb|AAH46522.1|/4.64666e-127/Acp1 protein, partial [Mus musculus]" 53330 2532 2.916666667 3.383333333 0.214124805 Up 0.261132423 Vamp4 vesicle-associated membrane protein 4 K08513|1|8e-54|214|pale:102883971|vesicle-associated membrane protein 4 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0033157//regulation of intracellular protein transport "gi|148707350|gb|EDL39297.1|/1.5541e-54/vesicle-associated membrane protein 4, isoform CRA_b, partial [Mus musculus]" 29869 5813 11.02333333 10.06 -0.13193024 Down 0.261132423 Ulk2 unc-51 like kinase 2 K08269|1|0.0|1764|mmu:29869|serine/threonine-protein kinase ULK/ATG1 [EC:2.7.11.1] GO:0012506//vesicle membrane;GO:0000407//pre-autophagosomal structure GO:0032550;GO:0004672//protein kinase activity GO:0007409//axonogenesis;GO:0007154//cell communication;GO:0006468//protein phosphorylation;GO:0030308//negative regulation of cell growth;GO:0006914//autophagy;GO:0006950//response to stress gi|49022835|dbj|BAC65613.2|/0/mKIAA0623 protein [Mus musculus] 76453 3226 3.433333333 2.963333333 -0.212389013 Down 0.261132423 Prss23 "protease, serine 23" K09627|1|0.0|773|mmu:76453|serine protease 23 [EC:3.4.21.-] GO:0043231//intracellular membrane-bounded organelle GO:0004175//endopeptidase activity GO:0019538//protein metabolic process "gi|148674837|gb|EDL06784.1|/0/protease, serine, 23, isoform CRA_b [Mus musculus]" 16426 2832 0.243333333 0.08 -1.604862058 Down 0.261104216 Itih3 "inter-alpha trypsin inhibitor, heavy chain 3" K19014|1|0.0|997|mdo:100619001|inter-alpha-trypsin inhibitor heavy chain H1 - GO:0004866//endopeptidase inhibitor activity GO:0030203//glycosaminoglycan metabolic process;GO:0051346//negative regulation of hydrolase activity gi|159110717|ref|NP_032433.2|/0/inter-alpha-trypsin inhibitor heavy chain H3 preproprotein [Mus musculus] 15547 3649.83 6.503333333 7.226666667 0.152150979 Up 0.261076009 Trmt2a TRM2 tRNA methyltransferase 2A K15332|1|0.0|1144|mmu:15547|tRNA (uracil-5-)-methyltransferase [EC:2.1.1.-] - GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity GO:0010467//gene expression;GO:0010467//gene expression;GO:0010467//gene expression gi|304555603|ref|NP_001182134.1|/0/tRNA (uracil-5-)-methyltransferase homolog A isoform 4 [Mus musculus] 74616 3247 7.29 6.573333333 -0.149293669 Down 0.261076009 Scrn3 secernin 3 K14358|1|0.0|851|mmu:74616|secernin - - - - 101359 3429 1.85 1.503333333 -0.299360338 Down 0.260981985 Prrt4 proline-rich transmembrane protein 4 K14573|1|8e-09|65.9|fpg:101921765|nucleolar protein 4 - - - gi|168229224|ref|NP_001094913.1|/0/proline-rich transmembrane protein 4 precursor [Mus musculus] 101706 7214 22.76333333 21.13 -0.107419066 Down 0.260972583 Numa1 nuclear mitotic apparatus protein 1 K16808|1|0.0|3359|mmu:101706|nuclear mitotic apparatus protein 1 GO:0043005//neuron projection;GO:0044297//cell body;GO:0034399//nuclear periphery;GO:0005819//spindle GO:0004673//protein histidine kinase activity;GO:0015631//tubulin binding GO:0040001//establishment of mitotic spindle localization;GO:0030855//epithelial cell differentiation gi|254675300|ref|NP_598708.3|/0/nuclear mitotic apparatus protein 1 [Mus musculus] 110253 2568 20.84333333 22.47 0.108414108 Up 0.260972583 Triobp TRIO and F-actin binding protein K20478|1|2e-24|119|sko:100372617|golgin subfamily B member 1;K02914|3|4e-16|91.3|mcc:100430923|large subunit ribosomal protein L34 GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle GO:0008289//lipid binding;GO:0003779//actin binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0008289//lipid binding;GO:0003779//actin binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0008289//lipid binding;GO:0003779//actin binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0008289//lipid binding;GO:0003779//actin binding;GO:0044389//ubiquitin-like protein ligase binding GO:0010770//positive regulation of cell morphogenesis involved in differentiation;GO:0010770//positive regulation of cell morphogenesis involved in differentiation;GO:0010770//positive regulation of cell morphogenesis involved in differentiation;GO:0010770//positive regulation of cell morphogenesis involved in differentiation gi|88501743|ref|NP_613045.3|/0/TRIO and F-actin-binding protein isoform 5 [Mus musculus] 26462 1922 20.65333333 22.28 0.109374589 Up 0.260972583 Txnrd2 thioredoxin reductase 2 K00384|1|0.0|993|mmu:26462|thioredoxin reductase (NADPH) [EC:1.8.1.9] GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0044297//cell body "GO:0042802//identical protein binding;GO:0000166//nucleotide binding;GO:0016209//antioxidant activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H" GO:0010035//response to inorganic substance;GO:0048534//hematopoietic or lymphoid organ development;GO:0044710;GO:0000302//response to reactive oxygen species;GO:0019725//cellular homeostasis "gi|182705231|sp|Q9JLT4.4|TRXR2_MOUSE/0/RecName: Full=Thioredoxin reductase 2, mitochondrial; AltName: Full=Thioredoxin reductase TR3; Flags: Precursor" 237433 1561 0.333333333 0.556666667 0.739848103 Up 0.260944375 Gm4925 predicted gene 4925 K02951|1|1e-70|270|mmu:237433|small subunit ribosomal protein S12e GO:0015935//small ribosomal subunit GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|81230474|ref|NP_001032243.1|/9.30667e-70/ribosomal protein S12-like [Mus musculus] 70235 1707 4.25 4.81 0.178574053 Up 0.260906766 Poc1a POC1 centriolar protein A K16482|1|0.0|791|mmu:70235|centriolar protein POC1 - - - - 329416 1820 4.103333333 4.66 0.183533599 Up 0.260906766 Nostrin nitric oxide synthase trafficker K20126|1|0.0|842|mmu:329416|nostrin - - - - 14433 1393.67 6256.7 6638.603333 0.085477821 Up 0.260812742 Gapdh glyceraldehyde-3-phosphate dehydrogenase K00134|1|0.0|670|mmu:14433|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0015631//tubulin binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0015631//tubulin binding" GO:0007010//cytoskeleton organization;GO:0070997//neuron death;GO:0031647//regulation of protein stability;GO:0012501//programmed cell death;GO:0006412//translation;GO:0006007//glucose catabolic process;GO:0018119//peptidyl-cysteine S-nitrosylation;GO:0044710;GO:1901698//response to nitrogen compound;GO:0034341//response to interferon-gamma;GO:0032502//developmental process;GO:0007010//cytoskeleton organization;GO:0070997//neuron death;GO:0031647//regulation of protein stability;GO:0012501//programmed cell death;GO:0006412//translation;GO:0006007//glucose catabolic process;GO:0018119//peptidyl-cysteine S-nitrosylation;GO:0044710;GO:1901698//response to nitrogen compound;GO:0034341//response to interferon-gamma;GO:0032502//developmental process gi|576080555|ref|NP_001276655.1|/0/glyceraldehyde-3-phosphate dehydrogenase isoform 1 [Mus musculus] 19053 1836 21.17 22.78666667 0.106168627 Up 0.260775133 Ppp2cb "protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform" K04382|1|0.0|656|pale:102887013|serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0008287//protein serine/threonine phosphatase complex;GO:0044444//cytoplasmic part;GO:0005819//spindle GO:0043169//cation binding;GO:0046983//protein dimerization activity;GO:0004721//phosphoprotein phosphatase activity GO:0009636//response to toxic substance;GO:0007265//Ras protein signal transduction;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0000302//response to reactive oxygen species;GO:0006915//apoptotic process;GO:0006464//cellular protein modification process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010467//gene expression gi|8394021|ref|NP_058736.1|/0/serine/threonine-protein phosphatase 2A catalytic subunit beta isoform [Rattus norvegicus] 12862 678 3552.566667 3349.156667 -0.085063859 Down 0.260737523 Cox6a2 cytochrome c oxidase subunit VIa polypeptide 2 K02266|1|3e-55|216|mmu:12862|cytochrome c oxidase subunit 6a GO:0005746//mitochondrial respiratory chain GO:0015002//heme-copper terminal oxidase activity GO:0044710 "gi|83816956|ref|NP_034073.2|/2.26582e-54/cytochrome c oxidase subunit 6A2, mitochondrial precursor [Mus musculus]" 14319 942 3057.886667 3264.523333 0.094337416 Up 0.260737523 Fth1 ferritin heavy polypeptide 1 K00522|1|3e-102|374|ngi:103740332|ferritin heavy chain [EC:1.16.3.2] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity;GO:0005506//iron ion binding;GO:0003824//catalytic activity;GO:0005506//iron ion binding GO:0044710;GO:0000041//transition metal ion transport;GO:0006879//cellular iron ion homeostasis;GO:0008285//negative regulation of cell proliferation;GO:0002376//immune system process;GO:0070265//necrotic cell death;GO:0044710;GO:0000041//transition metal ion transport;GO:0006879//cellular iron ion homeostasis;GO:0008285//negative regulation of cell proliferation;GO:0002376//immune system process;GO:0070265//necrotic cell death gi|58477732|gb|AAH89817.1|/1.20934e-120/Fth1 protein [Rattus norvegicus] 75607 7382.53 41.15333333 38.46333333 -0.097525495 Down 0.260699913 Wnk2 WNK lysine deficient protein kinase 2 K08867|1|0.0|3182|mmu:75607|WNK lysine deficient protein kinase [EC:2.7.11.1] - - - - 15353 1548.73 36.31666667 39.01 0.103212208 Up 0.260699913 Hmg20b high mobility group 20B "K11651|1|5e-12|75.1|tad:TRIADDRAFT_53566|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1;K10802|5|2e-09|66.2|cjo:107308252|high mobility group protein B1" GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0007519//skeletal muscle tissue development;GO:0016925//protein sumoylation;GO:0016568//chromatin modification;GO:0030182//neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0007519//skeletal muscle tissue development;GO:0016925//protein sumoylation;GO:0016568//chromatin modification;GO:0030182//neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0007519//skeletal muscle tissue development;GO:0016925//protein sumoylation;GO:0016568//chromatin modification;GO:0030182//neuron differentiation" "gi|148699476|gb|EDL31423.1|/1.11634e-123/high mobility group 20 B, isoform CRA_c, partial [Mus musculus]" 212483 4356 8.54 7.726666667 -0.144389909 Down 0.260624694 Fam193b "family with sequence similarity 193, member B" - - - - gi|50511191|dbj|BAD32581.1|/0/mKIAA1931 protein [Mus musculus] 18821 2357.79 1636.213333 1736.65 0.085946164 Up 0.26060589 Pln phospholamban - - - - "gi|148673139|gb|EDL05086.1|/4.03932e-07/phospholamban, partial [Mus musculus]" 67473 2634 21.78333333 20.17 -0.111013651 Down 0.260596487 Slc47a1 "solute carrier family 47, member 1" "K03327|1|0.0|963|mmu:67473|multidrug resistance protein, MATE family" GO:0031982//vesicle;GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0015893//drug transport;GO:0006812//cation transport gi|166197685|ref|NP_080459.2|/0/multidrug and toxin extrusion protein 1 [Mus musculus] 27360 4386.03 11.05333333 10.1 -0.130126213 Down 0.260596487 Add3 adducin 3 (gamma) K18622|1|0.0|1204|mmu:27360|adducin GO:0000228//nuclear chromosome;GO:0030054//cell junction;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0030054//cell junction;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0030054//cell junction;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0030054//cell junction;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0030054//cell junction;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0043169//cation binding;GO:0008092//cytoskeletal protein binding;GO:0019901//protein kinase binding;GO:0043169//cation binding;GO:0008092//cytoskeletal protein binding;GO:0019901//protein kinase binding;GO:0043169//cation binding;GO:0008092//cytoskeletal protein binding;GO:0019901//protein kinase binding;GO:0043169//cation binding;GO:0008092//cytoskeletal protein binding;GO:0019901//protein kinase binding;GO:0043169//cation binding;GO:0008092//cytoskeletal protein binding;GO:0019901//protein kinase binding GO:0042221//response to chemical;GO:0042221//response to chemical;GO:0042221//response to chemical;GO:0042221//response to chemical;GO:0042221//response to chemical "gi|148669741|gb|EDL01688.1|/0/adducin 3 (gamma), isoform CRA_b, partial [Mus musculus]" 218963 703 1.113333333 1.426666667 0.357762694 Up 0.260587085 Gm1821 ubiquitin pseudogene K08770|1|1e-79|297|oaa:100085779|ubiquitin C - - - gi|26353460|dbj|BAC40360.1|/2.24328e-79/unnamed protein product [Mus musculus] 76260 2287 1.426666667 1.113333333 -0.357762694 Down 0.260587085 Ttc8 tetratricopeptide repeat domain 8 K16781|1|0.0|1012|mmu:76260|tetratricopeptide repeat protein 8 GO:0005815//microtubule organizing center;GO:0043234//protein complex;GO:0031513//nonmotile primary cilium;GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0043234//protein complex;GO:0031090//organelle membrane;GO:0031513//nonmotile primary cilium GO:0005488//binding GO:0035295//tube development;GO:0007606//sensory perception of chemical stimulus;GO:0010927;GO:0040007//growth;GO:0021988//olfactory lobe development;GO:0006935//chemotaxis;GO:0001754//eye photoreceptor cell differentiation;GO:0008104//protein localization;GO:0035295//tube development;GO:0007606//sensory perception of chemical stimulus;GO:0010927;GO:0040007//growth;GO:0021988//olfactory lobe development;GO:0006935//chemotaxis;GO:0001754//eye photoreceptor cell differentiation;GO:0008104//protein localization gi|38146006|ref|NP_083829.1|/0/tetratricopeptide repeat protein 8 isoform 1 [Mus musculus] 66091 349 1149.343333 1222.7 0.089260643 Up 0.260483659 Ndufa3 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3" K03947|1|2e-44|179|mmu:66091|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3 GO:0031224//intrinsic component of membrane;GO:0005746//mitochondrial respiratory chain - GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy gi|21539587|ref|NP_079624.1|/1.55102e-43/NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 [Mus musculus] 237860 9112.46 13.52666667 14.68333333 0.118373154 Up 0.260446049 Ssh2 slingshot homolog 2 (Drosophila) K05766|1|0.0|2725|mmu:237860|protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48] GO:0043232;GO:0043232 GO:0008092//cytoskeletal protein binding;GO:0004721//phosphoprotein phosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0004721//phosphoprotein phosphatase activity GO:0007010//cytoskeleton organization;GO:0051128//regulation of cellular component organization;GO:0006796//phosphate-containing compound metabolic process;GO:0007010//cytoskeleton organization;GO:0051128//regulation of cellular component organization;GO:0006796//phosphate-containing compound metabolic process gi|37674238|ref|NP_808378.2|/0/protein phosphatase Slingshot homolog 2 isoform 1 [Mus musculus] 20544 4606 13.12333333 14.28 0.121861768 Up 0.260446049 Slc9a1 "solute carrier family 9 (sodium/hydrogen exchanger), member 1" "K05742|1|0.0|1431|mmu:20544|solute carrier family 9 (sodium/hydrogen exchanger), member 1" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0044459 GO:0005515//protein binding;GO:0005451//monovalent cation:proton antiporter activity GO:0001508//action potential;GO:0006818//hydrogen transport;GO:0008016//regulation of heart contraction;GO:0035725//sodium ion transmembrane transport;GO:0006461//protein complex assembly;GO:0010033//response to organic substance;GO:0010447//response to acidic pH;GO:0006915//apoptotic process;GO:0035051//cardiocyte differentiation;GO:0030641//regulation of cellular pH;GO:0019233//sensory perception of pain;GO:0016049//cell growth;GO:0046902//regulation of mitochondrial membrane permeability "gi|148698122|gb|EDL30069.1|/0/solute carrier family 9 (sodium/hydrogen exchanger), member 1, isoform CRA_a, partial [Mus musculus]" 170822 4207.39 6.02 5.37 -0.164841399 Down 0.260417842 Usp33 ubiquitin specific peptidase 33 K11848|1|0.0|1748|mmu:170822|ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12] - - - "gi|13529590|gb|AAH05506.1|/0/Usp33 protein, partial [Mus musculus]" 80285 3564 5.573333333 6.22 0.158374139 Up 0.260417842 Parp9 "poly (ADP-ribose) polymerase family, member 9" K15260|1|0.0|1579|mmu:80285|poly [ADP-ribose] polymerase 9 [EC:2.4.2.30] GO:0043231//intracellular membrane-bounded organelle "GO:0016763//transferase activity, transferring pentosyl groups" GO:0034341//response to interferon-gamma gi|13384918|ref|NP_084529.1|/0/poly [ADP-ribose] polymerase 9 [Mus musculus] 382137 1978 2.303333333 2.716666667 0.238114349 Up 0.260399037 Fdxacb1 ferredoxin-fold anticodon binding domain containing 1 "K03846|1|3e-116|421|asn:102374651|alpha-1,2-mannosyltransferase [EC:2.4.1.259 2.4.1.261]" - GO:0004812//aminoacyl-tRNA ligase activity;GO:0046872//metal ion binding;GO:0032550 GO:0006418//tRNA aminoacylation for protein translation "gi|148693816|gb|EDL25763.1|/0/RIKEN cDNA D630004A14, isoform CRA_a, partial [Mus musculus]" 69976 2534.68 3.706666667 3.22 -0.203061694 Down 0.260361428 Galk2 galactokinase 2 K18674|1|0.0|830|mmu:69976|N-acetylgalactosamine kinase [EC:2.7.1.157] - - - - 105734734 670 3.806666667 3.32 -0.197345003 Down 0.260361428 Gm11715 predicted gene 11715 K09228|1|3e-06|54.3|rno:102551340|KRAB domain-containing zinc finger protein - - - - 23997 1563 37.08333333 39.71 0.098731431 Up 0.260286209 Psmd13 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 13" K03039|1|0.0|737|mmu:23997|26S proteasome regulatory subunit N9 GO:0031981//nuclear lumen;GO:0022624//proteasome accessory complex;GO:0044444//cytoplasmic part - "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0006915//apoptotic process;GO:0044764;GO:0051320;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0007126//meiotic nuclear division;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|6755210|ref|NP_036005.1|/0/26S proteasome non-ATPase regulatory subunit 13 [Mus musculus] 75763 6962.8 1.293333333 0.996666667 -0.375911168 Down 0.260229794 Dcaf17 DDB1 and CUL4 associated factor 17 - GO:0031461//cullin-RING ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0032446//protein modification by small protein conjugation;GO:0032446//protein modification by small protein conjugation;GO:0032446//protein modification by small protein conjugation;GO:0032446//protein modification by small protein conjugation gi|260166698|ref|NP_001159452.1|/0/DDB1- and CUL4-associated factor 17 isoform a [Mus musculus] 54161 3818.65 21.02333333 22.61666667 0.105394882 Up 0.260182782 Copg1 "coatomer protein complex, subunit gamma 1" K17267|1|3e-48|194|ngi:103730333|coatomer subunit gamma GO:0030120//vesicle coat;GO:0030120//vesicle coat - GO:0051645//Golgi localization;GO:0015031//protein transport;GO:0010970//transport along microtubule;GO:0048193//Golgi vesicle transport;GO:0051645//Golgi localization;GO:0015031//protein transport;GO:0010970//transport along microtubule gi|47059163|ref|NP_957696.1|/4.30049e-56/coatomer subunit gamma-1 isoform 2 [Mus musculus] 19309 2887 854.0533333 801.3533333 -0.091887668 Down 0.26017338 Pygm muscle glycogen phosphorylase K00688|1|0.0|1660|mmu:19309|starch phosphorylase [EC:2.4.1.1] - - - - 268977 7209.79 7.1 6.393333333 -0.15125071 Down 0.260145173 Ltbp1 latent transforming growth factor beta binding protein 1 K19559|1|0.0|2989|mmu:268977|latent transforming growth factor beta binding protein 1 GO:0031012//extracellular matrix;GO:0031012//extracellular matrix GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway gi|46249419|ref|NP_064303.2|/0/latent-transforming growth factor beta-binding protein 1 isoform LTBP-1L precursor [Mus musculus] 75744 3077 7.286666667 6.58 -0.147171411 Down 0.260145173 Svip small VCP/p97-interacting protein - - - - "gi|148689942|gb|EDL21889.1|/1.17519e-48/mCG117948, partial [Mus musculus]" 66162 337 35.11333333 37.72 0.103310717 Up 0.26013577 Bola2 bolA-like 2 (E. coli) K05527|1|5e-11|68.2|mze:101469705|BolA protein - - - "gi|46016011|pdb|1V9J|A/5.94882e-43/Chain A, Solution Structure Of A Bola-Like Protein From Mus Musculus" 264134 4162 0.806666667 1.083333333 0.425432671 Up 0.260126368 Ttc26 tetratricopeptide repeat domain 26 K19685|1|0.0|1099|mmu:264134|intraflagellar transport protein 56 - - - - 433809 2479 14.49 13.34333333 -0.11893848 Down 0.260098161 Rnf207 ring finger protein 207 K11997|1|2e-14|84.3|bfo:BRAFLDRAFT_117133|tripartite motif-containing protein 2/3;K12035|3|6e-14|82.4|sko:100367035|tripartite motif-containing protein 71 [EC:2.3.2.27];K10054|5|2e-13|80.9|myb:102242938|probable transcription factor PML GO:0044464 GO:0046914//transition metal ion binding - gi|240849649|ref|NP_001028661.2|/0/RING finger protein 207 [Mus musculus] 13548 5894.94 13.57 14.72 0.117356951 Up 0.260098161 Dyrk1a dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a K08825|1|0.0|1318|mmu:13548|dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1] GO:0032991//macromolecular complex;GO:0016604//nuclear body;GO:0032991//macromolecular complex;GO:0016604//nuclear body GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0008092//cytoskeletal protein binding;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0008092//cytoskeletal protein binding "GO:0048731//system development;GO:0048511//rhythmic process;GO:0031401//positive regulation of protein modification process;GO:0006468//protein phosphorylation;GO:0006897//endocytosis;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0007049//cell cycle;GO:0048731//system development;GO:0048511//rhythmic process;GO:0031401//positive regulation of protein modification process;GO:0006468//protein phosphorylation;GO:0006897//endocytosis;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0007049//cell cycle" gi|24418935|ref|NP_031916.1|/0/dual specificity tyrosine-phosphorylation-regulated kinase 1A [Mus musculus] 71161 990 0.153333333 0.336666667 1.134649527 Up 0.260079356 Prkag2os1 "protein kinase, AMP-activated, gamma 2 non-catalytic subunit, opposite strand 1" - - - - "gi|148671140|gb|EDL03087.1|/9.18689e-82/mCG144533, partial [Mus musculus]" 68468 960 0.11 0.283333333 1.364996817 Up 0.260069954 Ly6g6c "lymphocyte antigen 6 complex, locus G6C" K06846|1|2e-58|228|mmu:68468|lymphocyte antigen 6 complex locus protein D/E/G6/H GO:0031224//intrinsic component of membrane - - "gi|148694727|gb|EDL26674.1|/3.31969e-65/lymphocyte antigen 6 complex, locus G6C, isoform CRA_b [Mus musculus]" 19156 2653.73 713.3433333 757.9766667 0.087556822 Up 0.260060551 Psap prosaposin K12382|1|0.0|1071|mmu:19156|saposin GO:0000323//lytic vacuole;GO:0044421;GO:0000323//lytic vacuole;GO:0044421;GO:0000323//lytic vacuole;GO:0044421;GO:0000323//lytic vacuole;GO:0044421;GO:0000323//lytic vacuole;GO:0044421;GO:0000323//lytic vacuole;GO:0044421 - GO:0006643//membrane lipid metabolic process;GO:0040007//growth;GO:0003006//developmental process involved in reproduction;GO:0010033//response to organic substance;GO:0000165//MAPK cascade;GO:0006643//membrane lipid metabolic process;GO:0040007//growth;GO:0003006//developmental process involved in reproduction;GO:0010033//response to organic substance;GO:0000165//MAPK cascade;GO:0006643//membrane lipid metabolic process;GO:0040007//growth;GO:0003006//developmental process involved in reproduction;GO:0010033//response to organic substance;GO:0000165//MAPK cascade;GO:0006643//membrane lipid metabolic process;GO:0040007//growth;GO:0003006//developmental process involved in reproduction;GO:0010033//response to organic substance;GO:0000165//MAPK cascade;GO:0006643//membrane lipid metabolic process;GO:0040007//growth;GO:0003006//developmental process involved in reproduction;GO:0010033//response to organic substance;GO:0000165//MAPK cascade;GO:0006643//membrane lipid metabolic process;GO:0040007//growth;GO:0003006//developmental process involved in reproduction;GO:0010033//response to organic substance;GO:0000165//MAPK cascade gi|225735651|ref|NP_001139593.1|/0/prosaposin isoform C precursor [Mus musculus] 329384 913 1.55 1.226666667 -0.33752495 Down 0.260051149 Ptrh1 peptidyl-tRNA hydrolase 1 homolog "K01056|1|1e-94|348|mmu:329384|peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]" - - - - 14719 2345 721.48 765.7233333 0.085863818 Up 0.260051149 Got2 "glutamatic-oxaloacetic transaminase 2, mitochondrial" "K14455|1|0.0|832|mmu:14719|aspartate aminotransferase, mitochondrial [EC:2.6.1.1]" GO:0032991//macromolecular complex;GO:0019866//organelle inner membrane;GO:0044429;GO:0043025//neuronal cell body GO:0070546;GO:0042802//identical protein binding;GO:0008289//lipid binding;GO:0031406//carboxylic acid binding;GO:0036137 GO:0097305//response to alcohol;GO:0006103//2-oxoglutarate metabolic process;GO:0009064//glutamine family amino acid metabolic process;GO:0006869//lipid transport;GO:0006531//aspartate metabolic process "gi|6754036|ref|NP_034455.1|/0/aspartate aminotransferase, mitochondrial [Mus musculus]" 112406 2124 35.39 37.97666667 0.101771519 Up 0.259966528 Egln2 egl-9 family hypoxia-inducible factor 2 K09592|1|0.0|760|mmu:112406|hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0019842//vitamin binding;GO:0046914//transition metal ion binding;GO:0031543//peptidyl-proline dioxygenase activity;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0019825//oxygen binding" GO:0009896;GO:0019471//4-hydroxyproline metabolic process;GO:0019725//cellular homeostasis;GO:0042981//regulation of apoptotic process;GO:0006950//response to stress gi|26344369|dbj|BAC35835.1|/0/unnamed protein product [Mus musculus] 382522 465 0.01 0.116666667 3.544320516 Up 0.259947723 Hist3h2bb-ps "histone cluster 3, H2bb, pseudogene" K11252|1|7e-46|184|tup:102490906|histone H2B - - - - 14311 1702 0.116666667 0.01 -3.544320516 Down 0.259947723 Cidec cell death-inducing DFFA-like effector c "K02310|1|1e-10|70.5|crg:105326479|DNA fragmentation factor, 45 kD, alpha subunit" GO:0043231//intracellular membrane-bounded organelle;GO:0005924//cell-substrate adherens junction;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0005924//cell-substrate adherens junction;GO:0044444//cytoplasmic part - "GO:0012502//induction of programmed cell death;GO:0006351//transcription, DNA-templated;GO:0012502//induction of programmed cell death;GO:0006351//transcription, DNA-templated" "gi|148667052|gb|EDK99468.1|/1.02099e-133/cell death-inducing DFFA-like effector c, isoform CRA_c, partial [Mus musculus]" 100041694 893 0.116666667 0.01 -3.544320516 Down 0.259947723 Gm10451 predicted gene 10451 - - - - gi|148704509|gb|EDL36456.1|/4.89203e-28/mCG7921 [Mus musculus] 20568 894 0.01 0.116666667 3.544320516 Up 0.259947723 Slpi secretory leukocyte peptidase inhibitor K04931|1|2e-13|78.6|cfr:102517018|potassium voltage-gated channel delayed-rectifier subfamily S member 1;K17106|2|7e-09|63.5|tup:102501520|whey acidic protein;K12864|3|2e-08|62.0|clv:102090334|beta-catenin-like protein 1 - GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0004857//enzyme inhibitor activity GO:0043393//regulation of protein binding;GO:0019079//viral genome replication;GO:0019538//protein metabolic process;GO:0051346//negative regulation of hydrolase activity gi|6755574|ref|NP_035544.1|/2.31373e-78/antileukoproteinase precursor [Mus musculus] 100862359 804 0.01 0.116666667 3.544320516 Up 0.259947723 Gm21671 "predicted gene, 21671" - - - - gi|528078326|ref|NP_001268445.1|/3.47309e-112/spermatogenesis associated glutamate (E)-rich protein-like [Mus musculus] 70157 458 0.01 0.116666667 3.544320516 Up 0.259947723 2210409D07Rik RIKEN cDNA 2210409D07 gene - - - - - 68230 402 0.01 0.116666667 3.544320516 Up 0.259947723 1700102H20Rik RIKEN cDNA 1700102H20 gene - - - - - 22240 5449.34 5.186666667 4.596666667 -0.174219603 Down 0.259947723 Dpysl3 dihydropyrimidinase-like 3 K07528|1|0.0|931|cjo:107323653|dihydropyrimidinase-like 2 GO:0043005//neuron projection;GO:0030133//transport vesicle;GO:0005884//actin filament;GO:0031252//cell leading edge;GO:0043005//neuron projection;GO:0030133//transport vesicle;GO:0005884//actin filament;GO:0031252//cell leading edge;GO:0044421;GO:0043005//neuron projection;GO:0030133//transport vesicle;GO:0005884//actin filament;GO:0031252//cell leading edge;GO:0044421 "GO:0019904//protein domain specific binding;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0005539//glycosaminoglycan binding;GO:0019904//protein domain specific binding;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0005539//glycosaminoglycan binding;GO:0019904//protein domain specific binding;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0005539//glycosaminoglycan binding" GO:0009611//response to wounding;GO:0031346//positive regulation of cell projection organization;GO:0010975//regulation of neuron projection development;GO:0034097//response to cytokine;GO:0051259//protein oligomerization;GO:0007015//actin filament organization;GO:0006206//pyrimidine nucleobase metabolic process;GO:0016477//cell migration;GO:0009611//response to wounding;GO:0031346//positive regulation of cell projection organization;GO:0010975//regulation of neuron projection development;GO:0034097//response to cytokine;GO:0051259//protein oligomerization;GO:0007015//actin filament organization;GO:0006935//chemotaxis;GO:0006206//pyrimidine nucleobase metabolic process;GO:0016477//cell migration;GO:0009611//response to wounding;GO:0031346//positive regulation of cell projection organization;GO:0010975//regulation of neuron projection development;GO:0034097//response to cytokine;GO:0051259//protein oligomerization;GO:0007015//actin filament organization;GO:0006935//chemotaxis;GO:0006206//pyrimidine nucleobase metabolic process;GO:0016477//cell migration gi|966949347|ref|XP_014996642.1|/0/PREDICTED: dihydropyrimidinase-related protein 3 isoform X1 [Macaca mulatta] 75406 758 614.7933333 653.52 0.088129867 Up 0.259919516 Ndufs7 NADH dehydrogenase (ubiquinone) Fe-S protein 7 K03940|1|2e-94|347|mmu:75406|NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain;GO:0044297//cell body;GO:0042995//cell projection GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0050136//NADH dehydrogenase (quinone) activity;GO:0048037//cofactor binding GO:0044710;GO:0010257//NADH dehydrogenase complex assembly;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization "gi|21312950|ref|NP_083548.1|/1.87568e-93/NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial precursor [Mus musculus]" 16656 9021 0.42 0.22 -0.932885804 Down 0.259891308 Hivep3 human immunodeficiency virus type I enhancer binding protein 3 K09239|1|0.0|3666|mmu:16656|human immunodeficiency virus type I enhancer-binding protein - - - - 69156 2241 1.936666667 2.316666667 0.258474814 Up 0.259872504 Comtd1 catechol-O-methyltransferase domain containing 1 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0008168//methyltransferase activity GO:0008152//metabolic process gi|33468999|ref|NP_081241.1|/1.00499e-126/catechol O-methyltransferase domain-containing protein 1 [Mus musculus] 14727 1233.64 1.913333333 2.293333333 0.261357828 Up 0.259872504 Lilr4b "leukocyte immunoglobulin-like receptor, subfamily B, member 4B" K06512|1|2e-153|499|mmu:14728|leukocyte immunoglobulin-like receptor GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0016020//membrane - - gi|631226380|ref|NP_001278822.1|/1.41577e-101/mast cell surface glycoprotein Gp49A isoform 3 precursor [Mus musculus] 93694 1214 19.43 21.00333333 0.112332408 Up 0.259750273 Clec2d "C-type lectin domain family 2, member d" K10072|1|4e-51|204|cge:100762568|C-type lectin domain family 2 member D GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0009986//cell surface GO:0005102//receptor binding;GO:0038023//signaling receptor activity GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0045953//negative regulation of natural killer cell mediated cytotoxicity;GO:0050851//antigen receptor-mediated signaling pathway;GO:0072657//protein localization to membrane;GO:0008064//regulation of actin polymerization or depolymerization;GO:0032663;GO:0001771//immunological synapse formation;GO:0042098//T cell proliferation gi|16716407|ref|NP_444339.1|/5.84708e-111/C-type lectin domain family 2 member D [Mus musculus] 97484 2134 12.89333333 14.03333333 0.122232438 Up 0.259665651 Cog8 component of oligomeric golgi complex 8 K20295|1|0.0|1172|mmu:97484|conserved oligomeric Golgi complex subunit 8 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0045184//establishment of protein localization gi|66392581|ref|NP_631975.3|/0/conserved oligomeric Golgi complex subunit 8 [Mus musculus] 20931 1170 12.79 13.92666667 0.122833727 Up 0.259665651 Surf2 surfeit gene 2 - - - - gi|7305529|ref|NP_038706.1|/1.34457e-141/surfeit locus protein 2 [Mus musculus] 24001 3963.84 1.736666667 1.396666667 -0.314333129 Down 0.25958103 Tiam2 T cell lymphoma invasion and metastasis 2 K16847|1|0.0|1239|mmu:24001|T-lymphoma invasion and metastasis-inducing protein 2 GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity;GO:0008289//lipid binding GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction gi|148669696|gb|EDL01643.1|/0/T-cell lymphoma invasion and metastasis 2 [Mus musculus] 382073 1175 4.166666667 4.716666667 0.178873958 Up 0.259552823 Ccdc84 coiled-coil domain containing 84 K04499|1|5e-59|230|mcf:102116128|RuvB-like protein 1 (pontin 52) - - - "gi|33416550|gb|AAH55929.1|/0/Coiled-coil domain containing 84, partial [Mus musculus]" 17533 5322 4.04 4.59 0.184138861 Up 0.259552823 Mrc1 "mannose receptor, C type 1" "K06560|1|0.0|2976|mmu:17533|mannose receptor, C type" GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0048029//monosaccharide binding;GO:0038023//signaling receptor activity GO:0007154//cell communication;GO:0006897//endocytosis gi|224967062|ref|NP_032651.2|/0/macrophage mannose receptor 1 precursor [Mus musculus] 20338 6218.69 10.82 9.893333333 -0.129171908 Down 0.259477604 Sel1l sel-1 suppressor of lin-12-like (C. elegans) K14026|1|0.0|1321|mmu:20338|SEL1 protein GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0007166//cell surface receptor signaling pathway;GO:0033554//cellular response to stress;GO:0007166//cell surface receptor signaling pathway;GO:0033554//cellular response to stress gi|60360536|dbj|BAD90512.1|/0/mKIAA4137 protein [Mus musculus] 18604 2279 450.05 477.5633333 0.085606781 Up 0.259458799 Pdk2 "pyruvate dehydrogenase kinase, isoenzyme 2" K00898|1|0.0|785|mmu:18604|pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2] GO:0031981//nuclear lumen;GO:0005759//mitochondrial matrix;GO:0043234//protein complex GO:0032550;GO:0004672//protein kinase activity;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding GO:0006094//gluconeogenesis;GO:0006086//acetyl-CoA biosynthetic process from pyruvate;GO:0033500//carbohydrate homeostasis;GO:0072331//signal transduction by p53 class mediator;GO:0031323//regulation of cellular metabolic process;GO:0055067;GO:0000302//response to reactive oxygen species;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006468//protein phosphorylation;GO:0007584//response to nutrient "gi|226958643|ref|NP_598428.2|/0/pyruvate dehydrogenase kinase, isoenzyme 2 [Mus musculus]" 107702 1667.83 34.92 37.43666667 0.100398425 Up 0.259430592 Rnh1 ribonuclease/angiogenin inhibitor 1 K16634|1|0.0|856|mmu:107702|ribonuclease inhibitor GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex GO:0004857//enzyme inhibitor activity;GO:0004857//enzyme inhibitor activity;GO:0004857//enzyme inhibitor activity GO:0001525//angiogenesis;GO:0044092//negative regulation of molecular function;GO:0001525//angiogenesis;GO:0044092//negative regulation of molecular function;GO:0001525//angiogenesis;GO:0044092//negative regulation of molecular function gi|285402659|ref|NP_001165572.1|/0/ribonuclease inhibitor isoform b [Mus musculus] 22359 8327 35.29333333 37.81333333 0.099499338 Up 0.259430592 Vldlr very low density lipoprotein receptor K20053|1|0.0|1658|mmu:22359|very low-density lipoprotein receptor GO:0031224//intrinsic component of membrane;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0034385;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0034385;GO:0044444//cytoplasmic part GO:0008565//protein transporter activity;GO:0046872//metal ion binding;GO:0030228//lipoprotein particle receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0071813//lipoprotein particle binding;GO:0030295//protein kinase activator activity;GO:0008565//protein transporter activity;GO:0046872//metal ion binding;GO:0030228//lipoprotein particle receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0071813//lipoprotein particle binding;GO:0030295//protein kinase activator activity GO:0032868//response to insulin;GO:0070555//response to interleukin-1;GO:0010876//lipid localization;GO:0021510//spinal cord development;GO:0021543//pallium development;GO:0015031//protein transport;GO:0016125//sterol metabolic process;GO:0001666//response to hypoxia;GO:0006897//endocytosis;GO:0009267//cellular response to starvation;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0034381//plasma lipoprotein particle clearance;GO:0010976//positive regulation of neuron projection development;GO:0045860//positive regulation of protein kinase activity;GO:0032496//response to lipopolysaccharide;GO:0032868//response to insulin;GO:0070555//response to interleukin-1;GO:0010876//lipid localization;GO:0021510//spinal cord development;GO:0021543//pallium development;GO:0015031//protein transport;GO:0016125//sterol metabolic process;GO:0001666//response to hypoxia;GO:0006897//endocytosis;GO:0009267//cellular response to starvation;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0034381//plasma lipoprotein particle clearance;GO:0010976//positive regulation of neuron projection development;GO:0045860//positive regulation of protein kinase activity;GO:0032496//response to lipopolysaccharide "gi|148709700|gb|EDL41646.1|/0/very low density lipoprotein receptor, isoform CRA_b, partial [Mus musculus]" 68750 8385.64 6.993333333 6.293333333 -0.152155913 Down 0.259411787 Rreb1 ras responsive element binding protein 1 K20210|1|0.0|2262|mmu:68750|ras-responsive element-binding protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0005622//intracellular;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|152060560|sp|Q3UH06.2|RREB1_MOUSE/7.31471e-167/RecName: Full=Ras-responsive element-binding protein 1; Short=RREB-1; AltName: Full=RAS-responsive zinc finger transcription factor RREB 66860 7797.19 7.283333333 6.58 -0.14651129 Down 0.259411787 Tanc1 "tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1" K15502|1|9e-43|179|spu:755512|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A GO:0044297//cell body;GO:0033267;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0044297//cell body;GO:0033267;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane - GO:0000768//syncytium formation by plasma membrane fusion;GO:0007632//visual behavior;GO:0043954//cellular component maintenance;GO:0000768//syncytium formation by plasma membrane fusion;GO:0007632//visual behavior;GO:0043954//cellular component maintenance gi|57164407|ref|NP_938036.2|/0/protein TANC1 isoform a [Mus musculus] 73368 4189 0.56 0.336666667 -0.73410594 Down 0.259280153 Col20a1 "collagen, type XX, alpha 1" "K08133|1|4e-137|492|amj:102567063|collagen, type XIV, alpha" - - - gi|258679414|ref|NP_082794.1|/0/collagen alpha-1(XX) chain precursor [Mus musculus] 18024 2458.38 35.96333333 38.46 0.096832017 Up 0.259270751 Nfe2l2 "nuclear factor, erythroid derived 2, like 2" - - - - - 266781 1941 33.85666667 36.36 0.102912259 Up 0.259270751 Snx17 sorting nexin 17 K17929|1|0.0|839|ngi:103735693|sorting nexin-17 GO:0005768//endosome;GO:0012506//vesicle membrane GO:0070325//lipoprotein particle receptor binding;GO:0005543//phospholipid binding GO:0044765//single-organism transport;GO:0006897//endocytosis;GO:0007154//cell communication;GO:0008203//cholesterol metabolic process;GO:0015031//protein transport gi|674053830|ref|XP_008833284.1|/0/PREDICTED: sorting nexin-17 isoform X1 [Nannospalax galili] 207165 11506 4.093333333 3.58 -0.193316567 Down 0.259242544 Bptf bromodomain PHD finger transcription factor K11728|1|0.0|4202|mmu:207165|nucleosome-remodeling factor subunit BPTF - - - gi|140969817|ref|NP_789820.2|/0/nucleosome-remodeling factor subunit BPTF [Mus musculus] 103573 4975.07 4.153333333 3.646666667 -0.18769133 Down 0.259242544 Xpo1 exportin 1 K14290|1|0.0|2142|mmu:103573|exportin-1 - - - - 109136 2843 13.35 14.48 0.117221861 Up 0.259223739 Mmaa methylmalonic aciduria (cobalamin deficiency) type A K07588|1|0.0|781|mmu:109136|LAO/AO transport system kinase [EC:2.7.-.-] GO:0043231//intracellular membrane-bounded organelle GO:0016462//pyrophosphatase activity;GO:0032550 - "gi|31541923|ref|NP_598584.2|/0/methylmalonic aciduria type A homolog, mitochondrial precursor [Mus musculus]" 107995 1793 2.15 1.78 -0.272459419 Down 0.259214337 Cdc20 cell division cycle 20 "K03363|1|0.0|969|mmu:107995|cell division cycle 20, cofactor of APC complex" GO:0005815//microtubule organizing center;GO:0000152//nuclear ubiquitin ligase complex;GO:0044444//cytoplasmic part GO:0005515//protein binding GO:0051094//positive regulation of developmental process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0008283//cell proliferation;GO:0048167//regulation of synaptic plasticity;GO:0010975//regulation of neuron projection development;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0007126//meiotic nuclear division;GO:0000087//mitotic M phase gi|165377264|ref|NP_075712.2|/0/cell division cycle protein 20 homolog [Mus musculus] 75578 1904 2.146666667 1.78 -0.270220946 Down 0.259214337 Fggy FGGY carbohydrate kinase domain containing - - "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0044238//primary metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0019725//cellular homeostasis;GO:0044238//primary metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0019725//cellular homeostasis gi|568929920|ref|XP_006503538.1|/0/PREDICTED: FGGY carbohydrate kinase domain-containing protein isoform X21 [Mus musculus] 30044 2237.66 1.763333333 2.133333333 0.274804183 Up 0.259214337 Opn4 opsin 4 (melanopsin) K04255|1|0.0|857|mmu:30044|r-opsin GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004930//G-protein coupled receptor activity;GO:0016918//retinal binding;GO:0004930//G-protein coupled receptor activity;GO:0016918//retinal binding GO:0009583//detection of light stimulus;GO:0050953//sensory perception of light stimulus;GO:0006464//cellular protein modification process;GO:0007623//circadian rhythm;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009583//detection of light stimulus;GO:0050953//sensory perception of light stimulus;GO:0006464//cellular protein modification process;GO:0007623//circadian rhythm;GO:0007186//G-protein coupled receptor signaling pathway gi|190610044|ref|NP_001122071.1|/0/melanopsin isoform 2 [Mus musculus] 104923 1676 34.27333333 36.75666667 0.100919428 Up 0.25914852 Adi1 acireductone dioxygenase 1 "K08967|1|1e-103|379|mmu:104923|1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase [EC:1.13.11.53 1.13.11.54]" GO:0031981//nuclear lumen;GO:0016020//membrane "GO:0043169//cation binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" GO:0000097//sulfur amino acid biosynthetic process;GO:0043102 "gi|19527270|ref|NP_598813.1|/1.20018e-102/1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase [Mus musculus]" 17067 834.93 373.0466667 350.1933333 -0.091204498 Down 0.25914852 Ly6c1 "lymphocyte antigen 6 complex, locus C1" K06846|1|6e-22|105|mmu:17067|lymphocyte antigen 6 complex locus protein D/E/G6/H GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane - - gi|355390366|ref|NP_001238985.1|/5.26883e-74/lymphocyte antigen 6C1 isoform 2 precursor [Mus musculus] 13132 4482.21 8.533333333 7.74 -0.140775838 Down 0.259110911 Dab2 "disabled 2, mitogen-responsive phosphoprotein" K12475|1|0.0|1296|mmu:13132|disabled homolog 2 GO:0044459;GO:0030136//clathrin-coated vesicle;GO:0005905//clathrin-coated pit "GO:0005102//receptor binding;GO:0005543//phospholipid binding;GO:0004872//receptor activity;GO:0032403//protein complex binding;GO:0030674//protein binding, bridging;GO:0043168//anion binding" GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001881//receptor recycling;GO:0006901//vesicle coating;GO:0007184//SMAD protein import into nucleus;GO:0006915//apoptotic process;GO:0030521//androgen receptor signaling pathway;GO:0032388//positive regulation of intracellular transport;GO:0043409//negative regulation of MAPK cascade;GO:0043009//chordate embryonic development;GO:0010770//positive regulation of cell morphogenesis involved in differentiation;GO:0016049//cell growth;GO:0001837//epithelial to mesenchymal transition;GO:0016477//cell migration;GO:0003008;GO:0070849//response to epidermal growth factor;GO:2000052//positive regulation of non-canonical Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0043393//regulation of protein binding;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0031331;GO:0000187//activation of MAPK activity gi|881087950|ref|NP_001297375.1|/0/disabled homolog 2 isoform d [Mus musculus] 66694 1313 361.5233333 383.9233333 0.08672948 Up 0.259101508 Uqcrfs1 "ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1" K00411|1|6e-142|506|mmu:66694|ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2] GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0005746//mitochondrial respiratory chain GO:0043169//cation binding;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0051536//iron-sulfur cluster binding;GO:0016491//oxidoreductase activity;GO:0005515//protein binding GO:0009636//response to toxic substance;GO:0044710;GO:0009719;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization "gi|13385168|ref|NP_079986.1|/4.65e-141/cytochrome b-c1 complex subunit Rieske, mitochondrial [Mus musculus]" 18685 3089.31 2.483333333 2.906666667 0.227087709 Up 0.258998082 Phtf1 putative homeodomain transcription factor 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|6523391|emb|CAB62242.1|/0/phtf protein [Mus musculus] 104015 7085 2.85 2.433333333 -0.228027956 Down 0.258998082 Synj1 synaptojanin 1 K20279|1|0.0|2544|ngi:103736463|synaptojanin [EC:3.1.3.36] - - - gi|755554744|ref|XP_011244377.1|/0/PREDICTED: synaptojanin-1 isoform X1 [Mus musculus] 56382 1448 19.69 21.22666667 0.108414724 Up 0.258960472 Rab9 "RAB9, member RAS oncogene family" K07899|1|3e-114|414|mmu:56382|Ras-related protein Rab-9A GO:0030666//endocytic vesicle membrane;GO:0000323//lytic vacuole;GO:0005768//endosome GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0006887//exocytosis;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction;GO:0001894//tissue homeostasis gi|9790227|ref|NP_062747.1|/2.75974e-113/ras-related protein Rab-9A [Mus musculus] 19219 3327 2.083333333 1.72 -0.276485124 Down 0.258941668 Ptger4 prostaglandin E receptor 4 (subtype EP4) K04261|1|0.0|924|mmu:19219|prostaglandin E receptor 4 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004955//prostaglandin receptor activity;GO:0004955//prostaglandin receptor activity GO:0001501//skeletal system development;GO:0050663//cytokine secretion;GO:0009612//response to mechanical stimulus;GO:0001503//ossification;GO:0032231//regulation of actin filament bundle assembly;GO:0002692//negative regulation of cellular extravasation;GO:0002294;GO:0031333//negative regulation of protein complex assembly;GO:0006954//inflammatory response;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0002237//response to molecule of bacterial origin;GO:0051403//stress-activated MAPK cascade;GO:0001501//skeletal system development;GO:0050663//cytokine secretion;GO:0009612//response to mechanical stimulus;GO:0001503//ossification;GO:0032231//regulation of actin filament bundle assembly;GO:0002692//negative regulation of cellular extravasation;GO:0002294;GO:0031333//negative regulation of protein complex assembly;GO:0006954//inflammatory response;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0002237//response to molecule of bacterial origin;GO:0051403//stress-activated MAPK cascade gi|6679531|ref|NP_032991.1|/0/prostaglandin E2 receptor EP4 subtype isoform 2 [Mus musculus] 20540 2189.62 2.05 1.69 -0.278600663 Down 0.258941668 Slc7a7 "solute carrier family 7 (cationic amino acid transporter, y+ system), member 7" "K13867|1|0.0|934|mmu:20540|solute carrier family 7 (L-type amino acid transporter), member 7" GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane GO:0046943//carboxylic acid transmembrane transporter activity;GO:0046943//carboxylic acid transmembrane transporter activity;GO:0046943//carboxylic acid transmembrane transporter activity GO:0046942//carboxylic acid transport;GO:0046942//carboxylic acid transport;GO:0046942//carboxylic acid transport gi|568987117|ref|XP_006518809.1|/0/PREDICTED: Y+L amino acid transporter 1 isoform X2 [Mus musculus] 68952 2329.24 9.633333333 10.55666667 0.132047375 Up 0.258885253 Fam57b "family with sequence similarity 57, member B" - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|226437643|ref|NP_081160.1|/1.46564e-138/protein FAM57B isoform 2 [Mus musculus] 53886 3990 1.016666667 0.743333333 -0.451765533 Down 0.258847644 Cdkl2 cyclin-dependent kinase-like 2 (CDC2-related kinase) K08824|1|0.0|1111|mmu:53886|cyclin-dependent kinase-like [EC:2.7.11.22] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|33859825|ref|NP_796244.2|/0/cyclin-dependent kinase-like 2 isoform 2 [Mus musculus] 321003 3236 1.113333333 0.83 -0.42370236 Down 0.258838241 Xpnpep3 "X-prolyl aminopeptidase 3, mitochondrial" K01262|1|0.0|790|mmu:321003|Xaa-Pro aminopeptidase [EC:3.4.11.9] - - - - 319468 6064.29 1.883333333 1.536666667 -0.293484117 Down 0.258800632 Ppm1h protein phosphatase 1H (PP2C domain containing) K17503|1|0.0|884|mmu:319468|protein phosphatase 1H [EC:3.1.3.16] - - - - 107895 3104 0.426666667 0.226666667 -0.912537159 Down 0.25875362 Mgat5 mannoside acetylglucosaminyltransferase 5 "K00744|1|0.0|1498|mmu:107895|alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase [EC:2.4.1.155]" GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane GO:0008375//acetylglucosaminyltransferase activity GO:0006487//protein N-linked glycosylation "gi|46047861|ref|NP_660110.2|/0/alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A [Mus musculus]" 11972 1617 33.26333333 35.69 0.101587152 Up 0.258744218 Atp6v0d1 "ATPase, H+ transporting, lysosomal V0 subunit D1" K02146|1|0.0|711|ocu:100350157|V-type H+-transporting ATPase subunit d GO:0033267;GO:0005774//vacuolar membrane;GO:0044459;GO:0030136//clathrin-coated vesicle;GO:0030666//endocytic vesicle membrane;GO:0033176//proton-transporting V-type ATPase complex;GO:0005768//endosome GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0005515//protein binding;GO:0019829//cation-transporting ATPase activity "GO:0006996//organelle organization;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0015031//protein transport;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0009154//purine ribonucleotide catabolic process;GO:0044403//symbiosis, encompassing mutualism through parasitism;GO:0007417//central nervous system development;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0006875//cellular metal ion homeostasis" gi|655790980|ref|XP_002711660.2|/0/PREDICTED: V-type proton ATPase subunit d 1 [Oryctolagus cuniculus] 12567 1365 32.99666667 35.43 0.102651175 Up 0.258744218 Cdk4 cyclin-dependent kinase 4 K02089|1|5e-171|603|ocu:100009039|cyclin-dependent kinase 4 [EC:2.7.11.22] GO:0031981//nuclear lumen;GO:0043296//apical junction complex;GO:0044427;GO:0005635//nuclear envelope;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0032550;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity GO:0048511//rhythmic process;GO:0044772//mitotic cell cycle phase transition;GO:0006412//translation;GO:0006915//apoptotic process;GO:0048545//response to steroid hormone;GO:0006796//phosphate-containing compound metabolic process;GO:0007154//cell communication;GO:0008284//positive regulation of cell proliferation;GO:0008361//regulation of cell size;GO:0051726//regulation of cell cycle;GO:0010038//response to metal ion;GO:0009887//organ morphogenesis;GO:0006464//cellular protein modification process;GO:0006950//response to stress gi|655881620|ref|XP_002720970.2|/3.86292e-170/PREDICTED: cyclin-dependent kinase 4 [Oryctolagus cuniculus] 98910 4663 1.41 1.103333333 -0.353826446 Down 0.258725413 Usp6nl USP6 N-terminal like K20133|1|0.0|1493|mmu:98910|USP6 N-terminal-like protein GO:0031982//vesicle;GO:0044464;GO:0031982//vesicle;GO:0044464 - GO:0006996//organelle organization;GO:0016192//vesicle-mediated transport;GO:0006996//organelle organization;GO:0016192//vesicle-mediated transport gi|37359738|dbj|BAC97847.1|/0/mKIAA0019 protein [Mus musculus] 70031 1064 12.92 14.04333333 0.120279345 Up 0.25871601 Cmtm8 CKLF-like MARVEL transmembrane domain containing 8 K05164|1|1e-15|86.3|acs:100553442|interleukin 17 receptor GO:0031224//intrinsic component of membrane;GO:0044421;GO:0043231//intracellular membrane-bounded organelle GO:0005102//receptor binding GO:0042221//response to chemical gi|21312514|ref|NP_081570.1|/2.22557e-84/CKLF-like MARVEL transmembrane domain-containing protein 8 [Mus musculus] 217692 7508 3.686666667 3.206666667 -0.201242586 Down 0.258697206 Sipa1l1 signal-induced proliferation-associated 1 like 1 K17701|1|0.0|3125|mmu:217692|signal-induced proliferation-associated 1 like protein 1 GO:0032991//macromolecular complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0044297//cell body;GO:0043232;GO:0032991//macromolecular complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0044297//cell body;GO:0043232 GO:0005102//receptor binding;GO:0008047//enzyme activator activity;GO:0003779//actin binding;GO:0019900//kinase binding;GO:0005102//receptor binding;GO:0008047//enzyme activator activity;GO:0003779//actin binding;GO:0019900//kinase binding GO:0007409//axonogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0050804//modulation of synaptic transmission;GO:0048814//regulation of dendrite morphogenesis;GO:0007409//axonogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0050804//modulation of synaptic transmission;GO:0048814//regulation of dendrite morphogenesis gi|269784721|ref|NP_001161455.1|/0/signal-induced proliferation-associated 1-like protein 1 isoform 2 [Mus musculus] 245857 2728 3.27 3.746666667 0.196316994 Up 0.258697206 Ssh3 slingshot homolog 3 (Drosophila) K05766|1|0.0|1122|mmu:245857|protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48] - - - gi|37674269|ref|NP_932781.1|/0/protein phosphatase Slingshot homolog 3 [Mus musculus] 11810 2209 3.226666667 3.703333333 0.198779864 Up 0.258697206 Apobec1 "apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1" K16932|1|1e-137|493|mmu:11810|C->U-editing enzyme APOBEC1 [EC:3.5.4.36] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0003723//RNA binding" GO:0031936//negative regulation of chromatin silencing;GO:0006216//cytidine catabolic process;GO:0032868//response to insulin;GO:0016553//base conversion or substitution editing;GO:0008283//cell proliferation;GO:0015031//protein transport;GO:0043488//regulation of mRNA stability;GO:0006396//RNA processing;GO:0002252;GO:0010038//response to metal ion;GO:0097305//response to alcohol;GO:0035510;GO:0010212//response to ionizing radiation;GO:0006950//response to stress;GO:0019538//protein metabolic process;GO:0031936//negative regulation of chromatin silencing;GO:0006216//cytidine catabolic process;GO:0032868//response to insulin;GO:0016553//base conversion or substitution editing;GO:0008283//cell proliferation;GO:0015031//protein transport;GO:0043488//regulation of mRNA stability;GO:0006396//RNA processing;GO:0002252;GO:0010038//response to metal ion;GO:0097305//response to alcohol;GO:0035510;GO:0010212//response to ionizing radiation;GO:0006950//response to stress;GO:0019538//protein metabolic process "gi|148667274|gb|EDK99690.1|/1.23924e-140/apolipoprotein B editing complex 1, isoform CRA_b, partial [Mus musculus]" 20583 2084 2.45 2.056666667 -0.252473761 Down 0.258687803 Snai2 snail family zinc finger 2 K05706|1|2e-130|469|mmu:20583|snail 2 GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin "GO:0003677//DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0046914//transition metal ion binding" "GO:0003272//endocardial cushion formation;GO:0010595//positive regulation of endothelial cell migration;GO:0002934//desmosome organization;GO:0050954//sensory perception of mechanical stimulus;GO:0035411//catenin import into nucleus;GO:0002062//chondrocyte differentiation;GO:0070830//bicellular tight junction assembly;GO:0000904//cell morphogenesis involved in differentiation;GO:0045444//fat cell differentiation;GO:0001649//osteoblast differentiation;GO:0070849//response to epidermal growth factor;GO:0010212//response to ionizing radiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0036119//response to platelet-derived growth factor;GO:0001817//regulation of cytokine production;GO:0016573//histone acetylation;GO:0008285//negative regulation of cell proliferation;GO:0071363//cellular response to growth factor stimulus;GO:0006929//substrate-dependent cell migration;GO:0043066//negative regulation of apoptotic process;GO:0010894//negative regulation of steroid biosynthetic process;GO:0014031//mesenchymal cell development" gi|6755576|ref|NP_035545.1|/1.51894e-129/zinc finger protein SNAI2 [Mus musculus] 72747 2401 2.036666667 2.43 0.254746435 Up 0.258687803 Ttc39c tetratricopeptide repeat domain 39C "K06240|1|6e-14|82.4|ecb:106780919|laminin, alpha 3/5" - - - gi|257467486|ref|NP_082617.2|/0/tetratricopeptide repeat protein 39C [Mus musculus] 381485 1787 34.75333333 32.33 -0.104277852 Down 0.258668998 Trim55 tripartite motif-containing 55 K10654|1|0.0|939|mmu:381485|tripartite motif-containing protein 55 - - - - 27214 2441.02 0.843333333 0.59 -0.515388025 Down 0.258650194 Dbf4 DBF4 zinc finger K06629|1|0.0|1258|mmu:27214|activator of S phase kinase - - - - 107605 3890 1.02 1.316666667 0.368321 Up 0.258650194 Rdh1 retinol dehydrogenase 1 (all trans) K11154|1|1e-164|583|mmu:19683|retinol dehydrogenase 16 [EC:1.1.1.-] GO:0044432;GO:0016021//integral component of membrane "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0036094//small molecule binding" GO:0002138//retinoic acid biosynthetic process gi|165377241|ref|NP_536684.2|/1.33803e-180/retinol dehydrogenase 16 precursor [Mus musculus] 54381 1927.89 19.27 20.79 0.109533187 Up 0.258640791 Cpq carboxypeptidase Q K01302|1|0.0|870|mmu:54381|carboxypeptidase Q [EC:3.4.17.-] GO:0000323//lytic vacuole;GO:0044421 GO:0043169//cation binding;GO:0042802//identical protein binding;GO:0008235//metalloexopeptidase activity GO:0006518//peptide metabolic process;GO:0009888//tissue development;GO:0019538//protein metabolic process;GO:0042403//thyroid hormone metabolic process "gi|148676915|gb|EDL08862.1|/0/plasma glutamate carboxypeptidase, isoform CRA_a, partial [Mus musculus]" 235606 2407 19.18 20.69666667 0.109795711 Up 0.258640791 Apeh acylpeptide hydrolase K01303|1|0.0|1501|mmu:235606|acylaminoacyl-peptidase [EC:3.4.19.1] GO:0005635//nuclear envelope GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|214010153|ref|NP_666338.2|/0/acylamino-acid-releasing enzyme [Mus musculus] 110842 1464 288.96 307.3766667 0.089137855 Up 0.258593779 Etfa "electron transferring flavoprotein, alpha polypeptide" K03522|1|6e-148|526|mmu:110842|electron transfer flavoprotein alpha subunit GO:0005759//mitochondrial matrix GO:0003824//catalytic activity;GO:0000166//nucleotide binding GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy "gi|227500281|ref|NP_663590.3|/5.07197e-147/electron transfer flavoprotein subunit alpha, mitochondrial [Mus musculus]" 66841 2281 272.2833333 290.56 0.093727431 Up 0.25855617 Etfdh "electron transferring flavoprotein, dehydrogenase" K00311|1|0.0|1292|mmu:66841|electron-transferring-flavoprotein dehydrogenase [EC:1.5.5.1] - - - - 19645 4642 5.25 4.673333333 -0.167865479 Down 0.25855617 Rb1 retinoblastoma 1 K06618|1|0.0|1739|mmu:19645|retinoblastoma-associated protein GO:0016604//nuclear body;GO:0005667//transcription factor complex;GO:0015630//microtubule cytoskeleton GO:0001085//RNA polymerase II transcription factor binding;GO:0044212//transcription regulatory region DNA binding;GO:0044389//ubiquitin-like protein ligase binding GO:0007224//smoothened signaling pathway;GO:0006325//chromatin organization;GO:0042692//muscle cell differentiation;GO:0007080//mitotic metaphase plate congression;GO:0007063//regulation of sister chromatid cohesion;GO:0000084//mitotic S phase;GO:0001933//negative regulation of protein phosphorylation;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000904//cell morphogenesis involved in differentiation;GO:0007091//metaphase/anaphase transition of mitotic cell cycle;GO:0008285//negative regulation of cell proliferation;GO:0034502//protein localization to chromosome;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0019216//regulation of lipid metabolic process;GO:0070997//neuron death;GO:0030218//erythrocyte differentiation;GO:0048469//cell maturation;GO:0007519//skeletal muscle tissue development;GO:0030030//cell projection organization;GO:0007064//mitotic sister chromatid cohesion gi|188528630|ref|NP_033055.2|/0/retinoblastoma-associated protein [Mus musculus] 16783 2239.1 286.6466667 304.8533333 0.088841818 Up 0.258537365 Lamp1 lysosomal-associated membrane protein 1 K06528|1|0.0|653|mmu:16783|lysosomal-associated membrane protein 1/2 - - - - 193742 1945 32.17333333 34.58 0.104072454 Up 0.258499756 Abhd16a abhydrolase domain containing 16A - GO:0031224//intrinsic component of membrane GO:0003824//catalytic activity - gi|30519896|ref|NP_848707.1|/0/protein ABHD16A [Mus musculus] 56370 1269 0.12 0.293333333 1.289506617 Up 0.258490353 Tagln3 transgelin 3 K20526|1|1e-119|432|bom:102265446|transgelin GO:0043231//intracellular membrane-bounded organelle - GO:0048513//animal organ development;GO:0006366//transcription from RNA polymerase II promoter gi|205755|gb|AAC42095.1|/1.04459e-119/neuronal protein [Rattus norvegicus] 99152 3021 19.67666667 21.18666667 0.106670783 Up 0.258452744 Anapc2 anaphase promoting complex subunit 2 K03349|1|0.0|1469|mmu:99152|anaphase-promoting complex subunit 2 GO:0031981//nuclear lumen;GO:0000152//nuclear ubiquitin ligase complex;GO:0044444//cytoplasmic part GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination;GO:0048731//system development;GO:0030307//positive regulation of cell growth;GO:0051094//positive regulation of developmental process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0048167//regulation of synaptic plasticity;GO:0031346//positive regulation of cell projection organization;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0048869//cellular developmental process gi|37360366|dbj|BAC98161.1|/0/mKIAA1406 protein [Mus musculus] 12520 1534 267.93 285.63 0.092291387 Up 0.258452744 Cd81 CD81 antigen K06508|1|4e-129|464|mmu:12520|CD81 antigen GO:0016021//integral component of membrane;GO:0044459 GO:0005488//binding GO:0033036;GO:0001934//positive regulation of protein phosphorylation;GO:0043126;GO:0046474//glycerophospholipid biosynthetic process;GO:0030888//regulation of B cell proliferation;GO:0019062//virion attachment to host cell;GO:0006950//response to stress;GO:0016049//cell growth gi|19526794|ref|NP_598416.1|/3.27229e-128/CD81 antigen [Mus musculus] 50773 820 8.34 7.556666667 -0.142297398 Down 0.258415134 Nt5c "5',3'-nucleotidase, cytosolic" K01081|1|1e-114|414|mmu:50773|5'-nucleotidase [EC:3.1.3.5] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0008252//nucleotidase activity;GO:0000166//nucleotide binding GO:0006244 "gi|7657031|ref|NP_056622.1|/8.50018e-114/5'(3')-deoxyribonucleotidase, cytosolic type [Mus musculus]" 16548 1452.81 6.22 6.91 0.15177113 Up 0.258377525 Khk ketohexokinase K00846|1|4e-171|603|mmu:16548|ketohexokinase [EC:2.7.1.3] GO:0044424 "GO:0032550;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032550" GO:0010038//response to metal ion;GO:0019318//hexose metabolic process;GO:0009746;GO:0043434//response to peptide hormone;GO:0034285;GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0043434//response to peptide hormone;GO:0009746;GO:0010038//response to metal ion;GO:0034285;GO:0019318//hexose metabolic process gi|887234222|ref|NP_001297454.1|/5.54932e-142/ketohexokinase isoform 3 [Mus musculus] 98404 3476 6.393333333 7.086666667 0.148538877 Up 0.258377525 AI597479 expressed sequence AI597479 K15432|1|3e-118|429|mmu:98404|ashwin GO:0043234//protein complex - - gi|19527038|ref|NP_598579.1|/2.42346e-117/ashwin [Mus musculus] 237943 6844 6.94 6.25 -0.151079473 Down 0.258377525 Gpatch8 G patch domain containing 8 - - GO:0046872//metal ion binding - gi|226958329|ref|NP_001152964.1|/0/G patch domain-containing protein 8 [Mus musculus] 18049 1095.6 7.18 6.49 -0.145765366 Down 0.258377525 Ngf nerve growth factor "K02582|1|1e-139|498|mcc:711681|nerve growth factor, beta" GO:0044421;GO:0044421 GO:0005123//death receptor binding;GO:0005123//death receptor binding GO:0001934//positive regulation of protein phosphorylation;GO:0030307//positive regulation of cell growth;GO:0007626//locomotory behavior;GO:0007611//learning or memory;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0007269//neurotransmitter secretion;GO:0008284//positive regulation of cell proliferation;GO:0030030//cell projection organization;GO:0009967//positive regulation of signal transduction;GO:0044093;GO:0007600//sensory perception;GO:0030182//neuron differentiation;GO:0001934//positive regulation of protein phosphorylation;GO:0030307//positive regulation of cell growth;GO:0007626//locomotory behavior;GO:0007611//learning or memory;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0007269//neurotransmitter secretion;GO:0008284//positive regulation of cell proliferation;GO:0030030//cell projection organization;GO:0009967//positive regulation of signal transduction;GO:0044093;GO:0007600//sensory perception;GO:0030182//neuron differentiation "gi|148675667|gb|EDL07614.1|/0/nerve growth factor, beta, isoform CRA_a, partial [Mus musculus]" 16500 11153 6.94 6.25 -0.151079473 Down 0.258377525 Kcnb1 "potassium voltage gated channel, Shab-related subfamily, member 1" K04885|1|0.0|1605|mmu:16500|potassium voltage-gated channel Shab-related subfamily B member 1 - - - gi|31560819|ref|NP_032446.2|/0/potassium voltage-gated channel subfamily B member 1 [Mus musculus] 54519 2540 4.646666667 4.106666667 -0.178228305 Down 0.25832111 Apbb1ip "amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein" K17704|1|0.0|877|mmu:54519|amyloid beta A4 precursor protein-binding family B member 1-interacting protein - - - - 74340 5086.81 4.6 4.056666667 -0.181339099 Down 0.25832111 Ahcyl2 S-adenosylhomocysteine hydrolase-like 2 K01251|1|0.0|1033|mmu:74340|adenosylhomocysteinase [EC:3.3.1.1] - GO:0003824//catalytic activity;GO:0036094//small molecule binding;GO:0016802;GO:0036094//small molecule binding;GO:0016802 GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process gi|953850655|ref|XP_014594557.1|/0/PREDICTED: adenosylhomocysteinase 3 isoform X2 [Equus caballus] 245944 4548.81 4.493333333 3.956666667 -0.183500562 Down 0.25832111 Vps54 VPS54 GARP complex subunit K17600|1|0.0|1875|mmu:245944|vacuolar protein sorting-associated protein 54 "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0016023//cytoplasmic, membrane-bounded vesicle" - GO:0045104//intermediate filament cytoskeleton organization;GO:0045184//establishment of protein localization;GO:0001894//tissue homeostasis;GO:0016192//vesicle-mediated transport;GO:0050879//multicellular organismal movement;GO:0045104//intermediate filament cytoskeleton organization;GO:0045184//establishment of protein localization;GO:0001894//tissue homeostasis;GO:0016192//vesicle-mediated transport;GO:0050879//multicellular organismal movement "gi|148675897|gb|EDL07844.1|/0/vacuolar protein sorting 54 (yeast), isoform CRA_a, partial [Mus musculus]" 15184 3881.56 34.38 36.77 0.096959632 Up 0.258311708 Hdac5 histone deacetylase 5 K11406|1|0.0|1719|mmu:15184|histone deacetylase 4/5 [EC:3.5.1.98] GO:0043234//protein complex;GO:0044451;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044451;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0044451;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044451;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044451;GO:0044444//cytoplasmic part "GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0043169//cation binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0043169//cation binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0043169//cation binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0043169//cation binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0043169//cation binding;GO:0000976//transcription regulatory region sequence-specific DNA binding" GO:0016525//negative regulation of angiogenesis;GO:0030098//lymphocyte differentiation;GO:0008284//positive regulation of cell proliferation;GO:0044093;GO:0006952//defense response;GO:0014070//response to organic cyclic compound;GO:0010830//regulation of myotube differentiation;GO:0001649//osteoblast differentiation;GO:0016575//histone deacetylation;GO:0051098//regulation of binding;GO:0033554//cellular response to stress;GO:0006366//transcription from RNA polymerase II promoter;GO:0060562//epithelial tube morphogenesis;GO:0016525//negative regulation of angiogenesis;GO:0030098//lymphocyte differentiation;GO:0008284//positive regulation of cell proliferation;GO:0044093;GO:0006952//defense response;GO:0014070//response to organic cyclic compound;GO:0010830//regulation of myotube differentiation;GO:0001649//osteoblast differentiation;GO:0016575//histone deacetylation;GO:0051098//regulation of binding;GO:0033554//cellular response to stress;GO:0006366//transcription from RNA polymerase II promoter;GO:0060562//epithelial tube morphogenesis;GO:0016525//negative regulation of angiogenesis;GO:0030098//lymphocyte differentiation;GO:0006325//chromatin organization;GO:0008284//positive regulation of cell proliferation;GO:0044093;GO:0006952//defense response;GO:0014070//response to organic cyclic compound;GO:0010830//regulation of myotube differentiation;GO:0001649//osteoblast differentiation;GO:0006476//protein deacetylation;GO:0051098//regulation of binding;GO:0033554//cellular response to stress;GO:0006366//transcription from RNA polymerase II promoter;GO:0060562//epithelial tube morphogenesis;GO:0016525//negative regulation of angiogenesis;GO:0030098//lymphocyte differentiation;GO:0008284//positive regulation of cell proliferation;GO:0044093;GO:0006952//defense response;GO:0014070//response to organic cyclic compound;GO:0010830//regulation of myotube differentiation;GO:0001649//osteoblast differentiation;GO:0016575//histone deacetylation;GO:0051098//regulation of binding;GO:0033554//cellular response to stress;GO:0006366//transcription from RNA polymerase II promoter;GO:0060562//epithelial tube morphogenesis;GO:0016525//negative regulation of angiogenesis;GO:0030098//lymphocyte differentiation;GO:0008284//positive regulation of cell proliferation;GO:0044093;GO:0006952//defense response;GO:0014070//response to organic cyclic compound;GO:0010830//regulation of myotube differentiation;GO:0001649//osteoblast differentiation;GO:0016575//histone deacetylation;GO:0051098//regulation of binding;GO:0033554//cellular response to stress;GO:0006366//transcription from RNA polymerase II promoter;GO:0060562//epithelial tube morphogenesis gi|118136295|ref|NP_001071164.1|/0/histone deacetylase 5 isoform 1 [Mus musculus] 76614 2549.62 298.0666667 280.9666667 -0.085236063 Down 0.258311708 Immt "inner membrane protein, mitochondrial" K17785|1|0.0|628|umr:103671463|mitofilin GO:0031304//intrinsic component of mitochondrial inner membrane;GO:0031304//intrinsic component of mitochondrial inner membrane;GO:0031304//intrinsic component of mitochondrial inner membrane;GO:0031304//intrinsic component of mitochondrial inner membrane - GO:0006874//cellular calcium ion homeostasis;GO:0006874//cellular calcium ion homeostasis;GO:0006874//cellular calcium ion homeostasis;GO:0006874//cellular calcium ion homeostasis gi|358439528|ref|NP_001240615.1|/0/MICOS complex subunit Mic60 isoform 3 [Mus musculus] 216197 2915 13.06666667 14.18 0.117966379 Up 0.258283501 Ckap4 cytoskeleton-associated protein 4 K13999|1|0.0|861|mmu:216197|cytoskeleton-associated protein 4 GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 - - gi|62526118|ref|NP_780660.1|/0/cytoskeleton-associated protein 4 [Mus musculus] 269061 3589.77 13.44666667 12.34 -0.123906189 Down 0.258283501 Cpsf7 cleavage and polyadenylation specific factor 7 K14398|1|1e-160|570|tup:102496014|cleavage and polyadenylation specificity factor subunit 6/7 GO:0043231//intracellular membrane-bounded organelle GO:1901363//heterocyclic compound binding;GO:0097159//organic cyclic compound binding - gi|970739387|ref|XP_006214939.2|/7.72969e-175/PREDICTED: cleavage and polyadenylation specificity factor subunit 7 isoform X1 [Vicugna pacos] 56016 1910 0.23 0.43 0.902702799 Up 0.258274098 Hebp2 heme binding protein 2 K01942|1|1e-87|326|tup:102498435|biotin--protein ligase [EC:6.3.4.9 6.3.4.10 6.3.4.11 6.3.4.15];K10502|2|8e-07|58.2|cmy:102947182|zinc finger and BTB domain-containing protein 22 GO:0043231//intracellular membrane-bounded organelle - - gi|9507129|ref|NP_062360.1|/9.44322e-115/heme-binding protein 2 [Mus musculus] 27401 3140 0.16 0.336666667 1.073248982 Up 0.258255294 Skp2 S-phase kinase-associated protein 2 (p45) K03875|1|0.0|860|mmu:27401|F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2) GO:0043231//intracellular membrane-bounded organelle;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0031461//cullin-RING ubiquitin ligase complex "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity" GO:0031668//cellular response to extracellular stimulus;GO:0044772//mitotic cell cycle phase transition;GO:0019941//modification-dependent protein catabolic process;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0016567//protein ubiquitination;GO:0006796//phosphate-containing compound metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0031668//cellular response to extracellular stimulus;GO:0044772//mitotic cell cycle phase transition;GO:0019941//modification-dependent protein catabolic process;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0016567//protein ubiquitination;GO:0006796//phosphate-containing compound metabolic process;GO:0008284//positive regulation of cell proliferation gi|7949135|ref|NP_038815.1|/0/S-phase kinase-associated protein 2 isoform a [Mus musculus] 16815 817 0.563333333 0.346666667 -0.700439718 Down 0.258208282 Lbx2 ladybird homeobox homolog 2 (Drosophila) K09353|1|9e-82|305|mmu:16815|homeobox protein LBX GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated" gi|80479165|gb|AAI09348.1|/7.22751e-81/Ladybird homeobox homolog 2 (Drosophila) [Mus musculus] 71449 2801 2.203333333 2.6 0.238823852 Up 0.25816127 Mettl13 methyltransferase like 13 K08513|1|0.0|982|cfa:480074|vesicle-associated membrane protein 4;K01415|2|2e-26|124|ssc:100627224|endothelin-converting enzyme [EC:3.4.24.71] - GO:0016741 GO:0008152//metabolic process gi|50510673|dbj|BAD32322.1|/0/mKIAA0859 protein [Mus musculus] 73233 3289 0.75 0.506666667 -0.565853678 Down 0.258076648 Zfp942 zinc finger protein 942 K09228|1|0.0|777|mmu:240038|KRAB domain-containing zinc finger protein - - - gi|312261244|ref|NP_001185977.1|/0/uncharacterized protein LOC73233 [Mus musculus] 50788 1901 1.563333333 1.24 -0.334285301 Down 0.258048441 Fbxl8 F-box and leucine-rich repeat protein 8 K10274|1|0.0|663|mmu:50788|F-box and leucine-rich repeat protein 8 - - - gi|255683411|ref|NP_056636.2|/0/F-box/LRR-repeat protein 8 [Mus musculus] 236790 3808 1.53 1.213333333 -0.334555703 Down 0.258048441 Ddx26b DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B K13180|1|0.0|1710|mmu:236790|ATP-dependent RNA helicase DDX26B [EC:3.6.4.-] - - - "gi|148710200|gb|EDL42146.1|/0/RIKEN cDNA 6330505F04, isoform CRA_b, partial [Mus musculus]" 80879 2386 1.24 1.56 0.331205908 Up 0.258048441 Slc16a3 "solute carrier family 16 (monocarboxylic acid transporters), member 3" "K08180|1|0.0|778|mmu:80879|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 3" GO:0005856//cytoskeleton;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0005856//cytoskeleton;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0005856//cytoskeleton;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0044763;GO:0006820//anion transport;GO:0044763;GO:0006820//anion transport;GO:0044763;GO:0006820//anion transport gi|13507630|ref|NP_109621.1|/0/monocarboxylate transporter 4 [Mus musculus] 69909 2326 0.603333333 0.856666667 0.505778662 Up 0.258010832 2610027K06Rik RIKEN cDNA 2610027K06 gene - - - - "gi|148683827|gb|EDL15774.1|/8.01774e-34/mCG146188, partial [Mus musculus]" 231887 2203 31.79333333 34.14 0.102738776 Up 0.258010832 Pdap1 PDGFA associated protein 1 - - - GO:0007165//signal transduction gi|694952508|ref|XP_009424630.1|/7.93517e-60/PREDICTED: uncharacterized protein LOC101058977 [Pan troglodytes] 320064 1705 0.576666667 0.823333333 0.513739004 Up 0.258010832 D130017N08Rik RIKEN cDNA D130017N08 gene - - - - - 215113 6969.5 6.156666667 5.526666667 -0.155739859 Down 0.258010832 Slc43a2 "solute carrier family 43, member 2" "K08229|1|0.0|1024|mmu:215113|MFS transporter, LAT3 family, solute carrier family 43, member 2" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0015171//amino acid transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity GO:0044763;GO:0006865//amino acid transport;GO:0044763;GO:0006865//amino acid transport;GO:0044763;GO:0006865//amino acid transport gi|27734186|ref|NP_775564.1|/0/large neutral amino acids transporter small subunit 4 [Mus musculus] 171168 2429 0.586666667 0.836666667 0.512111935 Up 0.258010832 Acer1 alkaline ceramidase 1 K01441|1|8e-151|536|mmu:171168|alkaline ceramidase [EC:3.5.1.23] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds" GO:0006670//sphingosine metabolic process;GO:0009913//epidermal cell differentiation;GO:0009268//response to pH;GO:0006796//phosphate-containing compound metabolic process;GO:0006672//ceramide metabolic process;GO:0051592//response to calcium ion "gi|148706267|gb|EDL38214.1|/1.8743e-150/N-acylsphingosine amidohydrolase (alkaline ceramidase) 3, partial [Mus musculus]" 666168 2447 0.353333333 0.17 -1.055495113 Down 0.257982624 Cyp4a31 "cytochrome P450, family 4, subfamily a, polypeptide 31" K07425|1|0.0|914|mmu:666168|alkane 1-monooxygenase [EC:1.14.15.3] GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0044459 "GO:0046914//transition metal ion binding;GO:0016713;GO:0046906//tetrapyrrole binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0008391//arachidonic acid monooxygenase activity;GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0008391//arachidonic acid monooxygenase activity;GO:0016713;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen" GO:0051791//medium-chain fatty acid metabolic process;GO:0032303;GO:0055065//metal ion homeostasis;GO:0036100;GO:0001977;GO:0019369//arachidonic acid metabolic process;GO:0044767//single-organism developmental process;GO:0019369//arachidonic acid metabolic process;GO:0032303;GO:0051791//medium-chain fatty acid metabolic process;GO:0036100 "gi|157384975|ref|NP_964002.2|/0/cytochrome P450, family 4, subfamily a, polypeptide 31 isoform 1 [Mus musculus]" 23942 3149 18.66 20.15 0.110830853 Up 0.257898003 Mta2 "metastasis-associated gene family, member 2" K11660|1|0.0|1272|mmu:23942|metastasis-associated protein MTA GO:0000118//histone deacetylase complex "GO:0046914//transition metal ion binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0001071//nucleic acid binding transcription factor activity;GO:0000988//transcription factor activity, protein binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0000975//regulatory region DNA binding" GO:0006476//protein deacetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006305;GO:0016568//chromatin modification gi|51491880|ref|NP_035972.3|/0/metastasis-associated protein MTA2 [Mus musculus] 101488 4632.64 7.733333333 8.5 0.136372442 Up 0.257785174 Slco2b1 "solute carrier organic anion transporter family, member 2b1" "K14352|1|0.0|1294|mmu:101488|solute carrier organic anion transporter family, member 2B" GO:0016323//basolateral plasma membrane;GO:0031224//intrinsic component of membrane;GO:0016323//basolateral plasma membrane;GO:0031224//intrinsic component of membrane;GO:0016323//basolateral plasma membrane;GO:0031224//intrinsic component of membrane GO:0005319//lipid transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity;GO:0005319//lipid transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity;GO:0005319//lipid transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity GO:0015718//monocarboxylic acid transport;GO:0071715;GO:0015718//monocarboxylic acid transport;GO:0071715;GO:0015718//monocarboxylic acid transport;GO:0071715 gi|357527418|ref|NP_001239459.1|/0/solute carrier organic anion transporter family member 2B1 isoform 1 [Mus musculus] 23969 4215 0.65 0.423333333 -0.618645627 Down 0.25776637 Pacsin1 protein kinase C and casein kinase substrate in neurons 1 K20123|1|0.0|849|mmu:23969|protein kinase C and casein kinase substrate in neurons protein GO:0005798//Golgi-associated vesicle;GO:0016020//membrane;GO:0005798//Golgi-associated vesicle;GO:0016020//membrane;GO:0005798//Golgi-associated vesicle;GO:0016020//membrane;GO:0005798//Golgi-associated vesicle;GO:0016020//membrane "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0008289//lipid binding;GO:0005515//protein binding" GO:0090150//establishment of protein localization to membrane;GO:0006996//organelle organization;GO:0007009//plasma membrane organization;GO:0006796//phosphate-containing compound metabolic process;GO:0010976//positive regulation of neuron projection development;GO:0006897//endocytosis;GO:0007154//cell communication;GO:0090150//establishment of protein localization to membrane;GO:0006996//organelle organization;GO:0007009//plasma membrane organization;GO:0006796//phosphate-containing compound metabolic process;GO:0010976//positive regulation of neuron projection development;GO:0006897//endocytosis;GO:0007154//cell communication;GO:0090150//establishment of protein localization to membrane;GO:0006996//organelle organization;GO:0007009//plasma membrane organization;GO:0006796//phosphate-containing compound metabolic process;GO:0010976//positive regulation of neuron projection development;GO:0006897//endocytosis;GO:0007154//cell communication;GO:0090150//establishment of protein localization to membrane;GO:0006996//organelle organization;GO:0007009//plasma membrane organization;GO:0006796//phosphate-containing compound metabolic process;GO:0010976//positive regulation of neuron projection development;GO:0006897//endocytosis;GO:0007154//cell communication gi|6754974|ref|NP_035991.1|/0/protein kinase C and casein kinase substrate in neurons protein 1 [Mus musculus] 11859 1609 0.65 0.423333333 -0.618645627 Down 0.25776637 Phox2a paired-like homeobox 2a K09330|1|2e-98|304|ecb:100052674|paired mesoderm homeobox protein 2 - - - - 21664 1953 9.463333333 10.36 0.130603655 Up 0.257747565 Phlda1 "pleckstrin homology like domain, family A, member 1" - GO:0031981//nuclear lumen;GO:0031982//vesicle;GO:0016020//membrane - GO:0012502//induction of programmed cell death;GO:0009101//glycoprotein biosynthetic process gi|226442929|ref|NP_033370.2|/5.6821e-123/pleckstrin homology-like domain family A member 1 [Mus musculus] 65960 4071 17.88333333 19.36666667 0.114959993 Up 0.25772876 Twsg1 twisted gastrulation BMP signaling modulator 1 K01810|1|8e-27|125|bmy:Bm1_47625|glucose-6-phosphate isomerase [EC:5.3.1.9] GO:0044421 GO:0005488//binding GO:0001654//eye development;GO:0048534//hematopoietic or lymphoid organ development;GO:0007420//brain development;GO:0030509//BMP signaling pathway;GO:0001649//osteoblast differentiation;GO:0007431//salivary gland development;GO:0001704//formation of primary germ layer gi|12746428|ref|NP_075540.1|/5.25635e-127/twisted gastrulation protein homolog 1 precursor [Mus musculus] 24109 2667 31.32333333 33.65 0.103368757 Up 0.25772876 Ubl3 ubiquitin-like 3 K14802|1|5e-29|132|bfo:BRAFLDRAFT_69708|phospholipid-transporting ATPase [EC:3.6.3.1] GO:0044464;GO:0016020//membrane - - gi|664700892|ref|XP_008515626.1|/1.4914e-63/PREDICTED: ubiquitin-like protein 3 [Equus przewalskii] 56215 3864.31 33.69666667 36.02333333 0.096325799 Up 0.25772876 Acin1 apoptotic chromatin condensation inducer 1 K12875|1|0.0|1672|mmu:56215|apoptotic chromatin condensation inducer in the nucleus GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0097159//organic cyclic compound binding;GO:0005515//protein binding GO:0012501//programmed cell death;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0022411;GO:0030261//chromosome condensation;GO:0009154//purine ribonucleotide catabolic process;GO:0012501//programmed cell death;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0022411;GO:0030261//chromosome condensation gi|149063915|gb|EDM14185.1|/0/apoptotic chromatin condensation inducer 1 [Rattus norvegicus] 320237 3064 0.023333333 0.156666667 2.74723393 Up 0.257653541 Smim10l2a small integral membrane protein 10 like 2A - - - - - 22431 3092 3.44 3.936666667 0.194565994 Up 0.257512505 Wt1 Wilms tumor 1 homolog K09234|1|0.0|935|mmu:22431|Wilms tumor protein 1 GO:0016604//nuclear body "GO:0043566//structure-specific DNA binding;GO:0019904//protein domain specific binding;GO:0000975//regulatory region DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0046914//transition metal ion binding" "GO:0055007//cardiac muscle cell differentiation;GO:0035502//metanephric part of ureteric bud development;GO:0006915//apoptotic process;GO:0008406//gonad development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0046546//development of primary male sexual characteristics;GO:0060538//skeletal muscle organ development;GO:0006396//RNA processing;GO:0016049//cell growth;GO:0051094//positive regulation of developmental process;GO:0032870//cellular response to hormone stimulus;GO:0001654//eye development;GO:0003382//epithelial cell morphogenesis;GO:0012502//induction of programmed cell death;GO:0035270//endocrine system development;GO:0061318;GO:0046622//positive regulation of organ growth;GO:0007354//zygotic determination of anterior/posterior axis, embryo;GO:0072125//negative regulation of glomerular mesangial cell proliferation;GO:0030198//extracellular matrix organization;GO:0051591//response to cAMP;GO:0006366//transcription from RNA polymerase II promoter;GO:0072050//S-shaped body morphogenesis;GO:0072164//mesonephric tubule development;GO:0048645//organ formation;GO:0006412//translation;GO:0051093//negative regulation of developmental process" gi|153281234|ref|NP_659032.3|/0/Wilms tumor protein homolog [Mus musculus] 66374 1659 12.29 13.37666667 0.12223374 Up 0.2574937 2310011J03Rik RIKEN cDNA 2310011J03 gene K08671|1|5e-29|131|nle:100602359|proprotein convertase subtilisin/kexin type 4 [EC:3.4.21.-] - - - - 107227 1284 203.9033333 217.1433333 0.0907623 Up 0.257474896 Macrod1 MACRO domain containing 1 K15212|1|1e-48|196|bfo:BRAFLDRAFT_123909|TATA box-binding protein-associated factor RNA polymerase I subunit A;K15261|2|9e-15|84.0|acs:100555773|poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30] GO:0043231//intracellular membrane-bounded organelle GO:0016787//hydrolase activity GO:0009116//nucleoside metabolic process gi|569006163|ref|XP_006526625.1|/1.50444e-141/PREDICTED: O-acetyl-ADP-ribose deacetylase MACROD1 isoform X1 [Mus musculus] 50794 6396 18 19.47333333 0.113502951 Up 0.257446688 Klf13 Kruppel-like factor 13 K09208|1|6e-85|319|mmu:50794|krueppel-like factor 9/13/14/16 - GO:0003676//nucleic acid binding GO:0030218//erythrocyte differentiation;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter gi|31981130|ref|NP_067341.2|/5.25835e-84/Krueppel-like factor 13 [Mus musculus] 67735 2122 0.166666667 0.343333333 1.042644337 Up 0.257380872 4930528A17Rik RIKEN cDNA 4930528A17 gene "K13170|1|3e-07|52.0|pps:100989173|splicing factor, arginine/serine-rich 18" - - - gi|12854451|dbj|BAB30033.1|/2.77102e-78/unnamed protein product [Mus musculus] 14911 2110 6.793333333 6.11 -0.152947266 Down 0.257380872 Thumpd3 THUMP domain containing 3 K11251|1|6e-43|178|tsp:Tsp_07029|histone H2A - GO:0003676//nucleic acid binding;GO:0016741 GO:0008152//metabolic process gi|6680129|ref|NP_032214.1|/0/THUMP domain-containing protein 3 [Mus musculus] 16897 4425 6.776666667 6.1 -0.151766567 Down 0.257380872 Llgl1 lethal giant larvae homolog 1 (Drosophila) K06094|1|0.0|1917|mmu:16897|lethal(2) giant larvae protein GO:0043005//neuron projection;GO:0005802//trans-Golgi network;GO:0015629//actin cytoskeleton;GO:0043209//myelin sheath;GO:0005769//early endosome;GO:0012505//endomembrane system;GO:0043005//neuron projection;GO:0005802//trans-Golgi network;GO:0015629//actin cytoskeleton;GO:0043209//myelin sheath;GO:0005769//early endosome;GO:0012505//endomembrane system GO:0017016//Ras GTPase binding;GO:0019900//kinase binding;GO:0017016//Ras GTPase binding;GO:0019900//kinase binding GO:0007417//central nervous system development;GO:0030036//actin cytoskeleton organization;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0065003;GO:0030011//maintenance of cell polarity;GO:0006892//post-Golgi vesicle-mediated transport;GO:0007417//central nervous system development;GO:0030036//actin cytoskeleton organization;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0065003;GO:0030011//maintenance of cell polarity;GO:0006892//post-Golgi vesicle-mediated transport gi|226874867|ref|NP_001152877.1|/0/lethal(2) giant larvae protein homolog 1 isoform 1 [Mus musculus] 406217 784 0.166666667 0.343333333 1.042644337 Up 0.257380872 Bex4 brain expressed X-linked 4 K12465|1|2e-10|68.6|hgl:101701538|nerve growth factor receptor-associated protein 1 GO:0043231//intracellular membrane-bounded organelle - - gi|47059053|ref|NP_997622.1|/9.73577e-48/protein BEX4 [Mus musculus] 73919 985.83 4.623333333 5.19 0.166801157 Up 0.257362067 Lyrm1 LYR motif containing 1 K18441|1|6e-18|94.4|smm:Smp_143390|cytohesin GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|21313200|ref|NP_083886.1|/1.58385e-63/LYR motif-containing protein 1 [Mus musculus] 19364 7016.56 4.446666667 5.013333333 0.1730459 Up 0.257362067 Rad51d RAD51 paralog D K10871|1|6e-122|395|mmu:19364|RAD51-like protein 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550" GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress "gi|148683730|gb|EDL15677.1|/1.09475e-140/RAD51-like 3 (S. cerevisiae), isoform CRA_d, partial [Mus musculus]" 242642 1602 1.876666667 2.243333333 0.257471583 Up 0.257352665 Hpdl 4-hydroxyphenylpyruvate dioxygenase-like K00457|1|2e-30|136|pxy:105385622|4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27] - "GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0043169//cation binding" GO:0006520//cellular amino acid metabolic process gi|22122847|ref|NP_666368.1|/0/4-hydroxyphenylpyruvate dioxygenase-like protein [Mus musculus] 217364 3922 1.906666667 2.276666667 0.255870432 Up 0.257352665 Engase endo-beta-N-acetylglucosaminidase K01227|1|0.0|1445|mmu:217364|mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase [EC:3.2.1.96] GO:0044424 "GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds" - gi|568973541|ref|XP_006533192.1|/0/PREDICTED: cytosolic endo-beta-N-acetylglucosaminidase isoform X2 [Mus musculus] 331623 6049 1.86 2.23 0.261741089 Up 0.257352665 Bend3 BEN domain containing 3 - - - - - 214048 1705 35.83333333 33.54 -0.095419565 Down 0.25733386 Larp1b "La ribonucleoprotein domain family, member 1B" K18757|1|9e-141|503|mmu:214048|la-related protein 1 - - - gi|625231805|ref|XP_007607049.1|/7.81801e-142/PREDICTED: la-related protein 1B isoform X10 [Cricetulus griseus] 64074 2832 33.20333333 35.48 0.095677926 Up 0.257249238 Smoc2 SPARC related modular calcium binding 2 K06826|1|1e-18|98.2|phi:102103630|nidogen (entactin) - - - gi|160333760|ref|NP_071710.2|/0/SPARC-related modular calcium-binding protein 2 precursor [Mus musculus] 433940 2717 1.05 1.35 0.362570079 Up 0.257239836 Fam222a "family with sequence similarity 222, member A" - - - - - 67160 1565 197.6133333 209.92 0.087159334 Up 0.257239836 Eef1g eukaryotic translation elongation factor 1 gamma K03233|1|0.0|864|nle:100606941|elongation factor 1-gamma GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0008135//translation factor activity, RNA binding" GO:0051707//response to other organism;GO:0006412//translation gi|914916139|ref|XP_005331561.2|/0/PREDICTED: speckle targeted PIP5K1A-regulated poly(A) polymerase isoform X1 [Ictidomys tridecemlineatus] 214616 2327 2.82 3.266666667 0.212124086 Up 0.257211629 Spata5l1 spermatogenesis associated 5-like 1 K14575|1|4e-118|428|cmk:103188326|AAA family ATPase GO:0044424 GO:0032550;GO:0016462//pyrophosphatase activity - gi|348041246|ref|NP_001028428.2|/0/spermatogenesis-associated protein 5-like protein 1 [Mus musculus] 67683 2315.99 2.903333333 3.35 0.206450877 Up 0.257211629 Pbdc1 polysaccharide biosynthesis domain containing 1 - - - - gi|13385810|ref|NP_080588.1|/1.36989e-93/protein PBDC1 isoform 1 [Mus musculus] 545893 1123 0.356666667 0.573333333 0.684797768 Up 0.257117605 Mansc4 MANSC domain containing 4 - - - - - 66404 2142 18.97666667 20.43 0.106462605 Up 0.257051788 Rtfdc1 replication termination factor 2 domain containing 1 - - - - "gi|148674659|gb|EDL06606.1|/6.49506e-176/mCG2574, partial [Mus musculus]" 67433 4826.79 18.04 19.49 0.111534752 Up 0.257051788 Ccdc127 coiled-coil domain containing 127 - - - - gi|74221276|dbj|BAE42124.1|/3.11063e-125/unnamed protein product [Mus musculus] 192197 3590.51 12.23333333 13.31666667 0.12241544 Up 0.257032984 Bcas3 breast carcinoma amplified sequence 3 - GO:0043231//intracellular membrane-bounded organelle;GO:0044424;GO:0044424 GO:0005488//binding - gi|262231842|ref|NP_619622.3|/0/breast carcinoma-amplified sequence 3 homolog isoform a [Mus musculus] 242362 4645 3.243333333 3.713333333 0.195237523 Up 0.256920155 Manea "mannosidase, endo-alpha" "K15538|1|0.0|945|mmu:242362|glycoprotein endo-alpha-1,2-mannosidase [EC:3.2.1.130]" GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0004559//alpha-mannosidase activity GO:0006487//protein N-linked glycosylation "gi|46048329|ref|NP_766453.2|/0/glycoprotein endo-alpha-1,2-mannosidase [Mus musculus]" 20358 6840.05 3.693333333 3.223333333 -0.196370087 Down 0.256920155 Sema6a "sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A" K06842|1|0.0|2020|mmu:20358|semaphorin 6 GO:0043005//neuron projection;GO:0016021//integral component of membrane GO:0005102//receptor binding;GO:0038023//signaling receptor activity GO:0001764//neuron migration;GO:0012501//programmed cell death;GO:0051640//organelle localization;GO:0006935//chemotaxis;GO:0007166//cell surface receptor signaling pathway gi|67846119|ref|NP_061214.2|/0/semaphorin-6A isoform 1 precursor [Mus musculus] 112405 3524 189.0866667 200.6566667 0.085681453 Up 0.256910753 Egln1 egl-9 family hypoxia-inducible factor 1 K09592|1|0.0|696|mmu:112405|hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29] GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0031543//peptidyl-proline dioxygenase activity GO:0001525//angiogenesis;GO:0003206//cardiac chamber morphogenesis;GO:0033483;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0000302//response to reactive oxygen species;GO:0044092//negative regulation of molecular function;GO:0001666//response to hypoxia;GO:0019471//4-hydroxyproline metabolic process gi|158303306|ref|NP_444437.2|/0/egl nine homolog 1 [Mus musculus] 27361 904 176.8966667 188.49 0.091581123 Up 0.256910753 Msrb1 methionine sulfoxide reductase B1 K07305|1|1e-64|248|mmu:27361|peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] - - - - 17536 4862.44 3.94 4.47 0.182079202 Up 0.256910753 Meis2 Meis homeobox 2 K16670|1|0.0|739|aml:100470022|homeobox protein Meis2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding" GO:0007423//sensory organ development;GO:0030099//myeloid cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007423//sensory organ development;GO:0030099//myeloid cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007423//sensory organ development;GO:0030099//myeloid cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007423//sensory organ development;GO:0030099//myeloid cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030099//myeloid cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007423//sensory organ development;GO:0030099//myeloid cell differentiation;GO:0006366//transcription from RNA polymerase II promoter "gi|148695936|gb|EDL27883.1|/0/myeloid ecotropic viral integration site-related gene 1, isoform CRA_b, partial [Mus musculus]" 18720 3676 7.33 8.09 0.142326504 Up 0.256891948 Pip5k1a "phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha" K00889|1|0.0|965|mmu:18720|1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68] GO:0016020//membrane;GO:0001726//ruffle;GO:0016604//nuclear body;GO:0016020//membrane;GO:0001726//ruffle;GO:0016604//nuclear body GO:0032550;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0019899//enzyme binding;GO:0032550;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0019899//enzyme binding GO:0001667//ameboidal-type cell migration;GO:0006612//protein targeting to membrane;GO:0007044//cell-substrate junction assembly;GO:0030036//actin cytoskeleton organization;GO:0046488//phosphatidylinositol metabolic process;GO:0030031//cell projection assembly;GO:0006935//chemotaxis;GO:0001667//ameboidal-type cell migration;GO:0006612//protein targeting to membrane;GO:0007044//cell-substrate junction assembly;GO:0030036//actin cytoskeleton organization;GO:0046488//phosphatidylinositol metabolic process;GO:0030031//cell projection assembly;GO:0006935//chemotaxis gi|31982833|ref|NP_032873.2|/0/phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform 2 [Mus musculus] 235041 4853 33.29666667 31.06 -0.100319926 Down 0.256882545 Kank2 KN motif and ankyrin repeat domains 2 K06269|1|8e-16|89.7|cmy:102942920|serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16];K15503|2|7e-14|83.2|aqu:100635111|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B - - - gi|160333753|ref|NP_663586.3|/0/KN motif and ankyrin repeat domain-containing protein 2 [Mus musculus] 11841 2269 9.27 10.15 0.130838483 Up 0.256647486 Arf2 ADP-ribosylation factor 2 K06883|1|2e-99|365|ecb:100049809|uncharacterized protein GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0032550;GO:0032550 GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization;GO:0006810//transport;GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization;GO:0006810//transport "gi|149054474|gb|EDM06291.1|/4.71384e-118/ADP-ribosylation factor 2, isoform CRA_c [Rattus norvegicus]" 212139 3349 9.27 10.15 0.130838483 Up 0.256647486 Cc2d1a coiled-coil and C2 domain containing 1A K18260|1|0.0|1624|mmu:212139|coiled-coil and C2 domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle "GO:0060089;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding" "GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006351//transcription, DNA-templated" "gi|148678987|gb|EDL10934.1|/0/mCG5898, isoform CRA_a, partial [Mus musculus]" 71729 4680.24 9 9.88 0.13458604 Up 0.256647486 Rgs12 regulator of G-protein signaling 12 K16449|1|0.0|2401|mmu:71729|regulator of G-protein signaling GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0030425//dendrite;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0030425//dendrite;GO:0044444//cytoplasmic part GO:0004871//signal transducer activity;GO:0008047//enzyme activator activity;GO:0060589;GO:0005488//binding;GO:0004871//signal transducer activity;GO:0008047//enzyme activator activity;GO:0060589;GO:0005488//binding GO:0043087//regulation of GTPase activity;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0043087//regulation of GTPase activity;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway gi|254553475|ref|NP_001156984.1|/0/regulator of G-protein signaling 12 isoform B [Mus musculus] 21821 3097 1.716666667 2.073333333 0.272342148 Up 0.256638083 Ift88 intraflagellar transport 88 K16474|1|0.0|1563|mmu:21821|intraflagellar transport protein 88 GO:0031513//nonmotile primary cilium;GO:0005813//centrosome;GO:0005930//axoneme GO:0005488//binding GO:0033036;GO:0003206//cardiac chamber morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0001944//vasculature development;GO:0051604//protein maturation;GO:0030900//forebrain development;GO:0009855//determination of bilateral symmetry;GO:0030326//embryonic limb morphogenesis;GO:0043009//chordate embryonic development;GO:0000904//cell morphogenesis involved in differentiation;GO:0030323//respiratory tube development;GO:0042475//odontogenesis of dentin-containing tooth;GO:0048858//cell projection morphogenesis;GO:0006508//proteolysis;GO:0009953//dorsal/ventral pattern formation gi|239915965|ref|NP_033402.2|/0/intraflagellar transport protein 88 homolog [Mus musculus] 80912 4972.6 19.58 18.15 -0.109411217 Down 0.256628681 Pum1 pumilio RNA-binding family member 1 K17943|1|0.0|1812|mmu:80912|pumilio RNA-binding family GO:0044424;GO:0044424;GO:0044424 - GO:0006412//translation;GO:0006412//translation;GO:0006412//translation gi|28972067|dbj|BAC65487.1|/0/mKIAA0099 protein [Mus musculus] 50933 947 19.91333333 18.48666667 -0.107249621 Down 0.256628681 Uchl3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) K05609|1|2e-130|467|mmu:50933|ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle "GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016790//thiolester hydrolase activity;GO:0032182//ubiquitin-like protein binding" GO:0043010//camera-type eye development;GO:0008344//adult locomotory behavior;GO:0019941//modification-dependent protein catabolic process;GO:0032868//response to insulin;GO:0045444//fat cell differentiation;GO:0007631//feeding behavior gi|139948802|ref|NP_057932.2|/1.88306e-129/ubiquitin carboxyl-terminal hydrolase isozyme L3 [Mus musculus] 66442 1388 0.596666667 0.846666667 0.50486891 Up 0.256572267 Spc25 "SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)" "K11550|1|4e-89|330|mmu:66442|kinetochore protein Spc25, animal type" GO:0000776//kinetochore;GO:0043231//intracellular membrane-bounded organelle;GO:0000776//kinetochore;GO:0043231//intracellular membrane-bounded organelle;GO:0000776//kinetochore;GO:0043231//intracellular membrane-bounded organelle;GO:0000776//kinetochore;GO:0043231//intracellular membrane-bounded organelle - GO:0000087//mitotic M phase;GO:0000087//mitotic M phase;GO:0000087//mitotic M phase;GO:0000087//mitotic M phase "gi|148695081|gb|EDL27028.1|/3.20609e-88/spindle pole body component 25 homolog (S. cerevisiae), isoform CRA_b, partial [Mus musculus]" 18574 3253.12 1.306666667 1.63 0.318980811 Up 0.256572267 Pde1b "phosphodiesterase 1B, Ca2+-calmodulin dependent" "K13755|1|0.0|978|mmu:18574|calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]" GO:0031981//nuclear lumen;GO:0044297//cell body "GO:0005515//protein binding;GO:0043169//cation binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity" GO:0014075//response to amine;GO:0002573//myeloid leukocyte differentiation;GO:0036005;GO:0007632//visual behavior;GO:0042069//regulation of catecholamine metabolic process;GO:0046058//cAMP metabolic process;GO:0042430//indole-containing compound metabolic process;GO:0007268//chemical synaptic transmission;GO:0071345//cellular response to cytokine stimulus;GO:0009154//purine ribonucleotide catabolic process "gi|560961439|ref|XP_006203163.1|/0/PREDICTED: calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B isoform X1 [Vicugna pacos]" 68219 1111 12.71 13.78 0.116611858 Up 0.256572267 Nudt21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 K14397|1|3e-132|473|shr:100915903|cleavage and polyadenylation specificity factor subunit 5 GO:0005815//microtubule organizing center;GO:0043234//protein complex;GO:0016604//nuclear body GO:0003723//RNA binding;GO:0042802//identical protein binding;GO:0019899//enzyme binding;GO:0003824//catalytic activity GO:0051259//protein oligomerization;GO:0000377;GO:0031124//mRNA 3'-end processing;GO:0006366//transcription from RNA polymerase II promoter gi|13386106|ref|NP_080899.1|/2.61066e-131/cleavage and polyadenylation specificity factor subunit 5 [Mus musculus] 237360 5188 0.86 0.606666667 -0.503432615 Down 0.256572267 Adamts14 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14" K08628|1|0.0|2494|mmu:237360|a disintegrin and metalloproteinase with thrombospondin motifs 14 [EC:3.4.24.-] - "GO:0043169//cation binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0030198//extracellular matrix organization gi|124487465|ref|NP_001074596.1|/0/A disintegrin and metalloproteinase with thrombospondin motifs 14 precursor [Mus musculus] 380916 4665.82 6.663333333 5.99 -0.153688063 Down 0.256497048 Lrch1 leucine-rich repeats and calponin homology (CH) domain containing 1 K10130|1|2e-19|101|sko:102800700|leucine-rich repeats and death domain-containing protein;K19613|3|1e-16|92.4|acs:100562674|leucine-rich repeat protein SHOC2 - - - gi|74180769|dbj|BAE25596.1|/0/unnamed protein product [Mus musculus] 100604 2829 6.893333333 6.226666667 -0.146741731 Down 0.256497048 Lrrc8c "leucine rich repeat containing 8 family, member C" K19613|1|2e-31|140|bfo:BRAFLDRAFT_214464|leucine-rich repeat protein SHOC2 GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane - - gi|19923058|ref|NP_598658.1|/0/volume-regulated anion channel subunit LRRC8C [Mus musculus] 13603 1783 1.35 1.676666667 0.312636492 Up 0.256487645 Opn3 opsin 3 K04256|1|0.0|636|mmu:13603|c-opsin GO:0016021//integral component of membrane GO:0004930//G-protein coupled receptor activity GO:0007623//circadian rhythm;GO:0009583//detection of light stimulus;GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process gi|6753710|ref|NP_034228.1|/5.89504e-180/opsin-3 [Mus musculus] 12797 1987 1.713333333 1.383333333 -0.308657023 Down 0.256487645 Cnn1 calponin 1 "K07441|1|3e-95|352|gga:424484|beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141];K09228|2|7e-49|197|cfa:491863|KRAB domain-containing zinc finger protein;K20526|3|1e-36|157|obi:106880419|transgelin" GO:0043232 GO:0005515//protein binding GO:0030036//actin cytoskeleton organization gi|675758093|ref|XP_002761811.2|/8.46057e-160/PREDICTED: calponin-1 isoform X1 [Callithrix jacchus] 14339 2139.54 29.34333333 31.53 0.103692403 Up 0.256431231 Aktip thymoma viral proto-oncogene 1 interacting protein K02207|1|2e-06|57.4|cbr:CBG22149|ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23];K10573|2|3e-06|56.6|tsp:Tsp_05222|ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0005774//vacuolar membrane;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0005774//vacuolar membrane;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0005774//vacuolar membrane;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0005774//vacuolar membrane;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0005774//vacuolar membrane GO:0005488//binding;GO:0016881//acid-amino acid ligase activity;GO:0005488//binding;GO:0016881//acid-amino acid ligase activity;GO:0005488//binding;GO:0016881//acid-amino acid ligase activity;GO:0005488//binding;GO:0016881//acid-amino acid ligase activity;GO:0005488//binding;GO:0016881//acid-amino acid ligase activity GO:0016192//vesicle-mediated transport;GO:0012501//programmed cell death;GO:0007041//lysosomal transport;GO:0001932//regulation of protein phosphorylation;GO:0043393//regulation of protein binding;GO:0045184//establishment of protein localization;GO:0007033//vacuole organization;GO:0016192//vesicle-mediated transport;GO:0012501//programmed cell death;GO:0007041//lysosomal transport;GO:0001932//regulation of protein phosphorylation;GO:0043393//regulation of protein binding;GO:0045184//establishment of protein localization;GO:0007033//vacuole organization;GO:0016192//vesicle-mediated transport;GO:0012501//programmed cell death;GO:0007041//lysosomal transport;GO:0001932//regulation of protein phosphorylation;GO:0043393//regulation of protein binding;GO:0045184//establishment of protein localization;GO:0007033//vacuole organization;GO:0016192//vesicle-mediated transport;GO:0012501//programmed cell death;GO:0007041//lysosomal transport;GO:0001932//regulation of protein phosphorylation;GO:0043393//regulation of protein binding;GO:0045184//establishment of protein localization;GO:0007033//vacuole organization;GO:0016192//vesicle-mediated transport;GO:0012501//programmed cell death;GO:0007041//lysosomal transport;GO:0001932//regulation of protein phosphorylation;GO:0043393//regulation of protein binding;GO:0045184//establishment of protein localization;GO:0007033//vacuole organization gi|6753918|ref|NP_034371.1|/5.6278e-170/AKT-interacting protein isoform 1 [Mus musculus] 243374 3568.72 1.983333333 1.633333333 -0.280107919 Down 0.256384219 Gimap8 "GTPase, IMAP family member 8" - - - - - 66526 6243 1.62 1.966666667 0.279758641 Up 0.256384219 Tceanc2 transcription elongation factor A (SII) N-terminal and central domain containing 2 - GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0010467//gene expression gi|13385072|ref|NP_079893.1|/6.4168e-111/transcription elongation factor A N-terminal and central domain-containing protein 2 [Mus musculus] 13929 2820.93 30.37666667 32.55666667 0.099989429 Up 0.256243183 Amz2 archaelysin family metallopeptidase 2 K06974|1|0.0|751|mmu:13929|archaemetzincin [EC:3.4.-.-] - "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0019538//protein metabolic process gi|75812978|ref|NP_079551.3|/0/archaemetzincin-2 [Mus musculus] 17347 3448 158.92 148.8366667 -0.094570713 Down 0.256224379 Mknk2 MAP kinase-interacting serine/threonine kinase 2 K04372|1|0.0|908|mmu:17347|MAP kinase interacting serine/threonine kinase [EC:2.7.11.1] GO:0016604//nuclear body GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity GO:0006412//translation;GO:0012501//programmed cell death;GO:0048534//hematopoietic or lymphoid organ development;GO:0035556//intracellular signal transduction;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0046685//response to arsenic-containing substance gi|700584894|ref|NP_067437.2|/0/MAP kinase-interacting serine/threonine-protein kinase 2 [Mus musculus] 72519 2280 12.46333333 13.52333333 0.117760831 Up 0.256224379 Tmem55a transmembrane protein 55A "K13084|1|3e-152|541|mmu:72519|phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78]" GO:0031224//intrinsic component of membrane;GO:0005770//late endosome;GO:0000323//lytic vacuole GO:0003824//catalytic activity - "gi|21312268|ref|NP_082540.1|/2.68365e-151/type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [Mus musculus]" 107771 861 11.99333333 13.05 0.121817121 Up 0.256224379 Bmyc brain expressed myelocytomatosis oncogene K09111|1|2e-92|340|mmu:107771|brain expressed myelocytomatosis oncogene;K04377|3|9e-46|186|rno:24577|Myc proto-oncogene protein GO:0044451;GO:0015630//microtubule cytoskeleton;GO:0043005//neuron projection;GO:0032991//macromolecular complex GO:0008134//transcription factor binding;GO:0043566//structure-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding "GO:0000737//DNA catabolic process, endonucleolytic;GO:0000085//mitotic G2 phase;GO:0060070//canonical Wnt signaling pathway;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0009743//response to carbohydrate;GO:0021536//diencephalon development;GO:0006875//cellular metal ion homeostasis;GO:0070555//response to interleukin-1;GO:0045838//positive regulation of membrane potential;GO:0001501//skeletal system development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0007006//mitochondrial membrane organization;GO:0051726//regulation of cell cycle;GO:0001783//B cell apoptotic process;GO:0035879//plasma membrane lactate transport;GO:0010212//response to ionizing radiation;GO:0008637//apoptotic mitochondrial changes;GO:0050877//neurological system process;GO:0008285//negative regulation of cell proliferation;GO:0016568//chromatin modification;GO:0006754//ATP biosynthetic process;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006974//cellular response to DNA damage stimulus;GO:0042471//ear morphogenesis;GO:0031325//positive regulation of cellular metabolic process;GO:0007519//skeletal muscle tissue development;GO:0010829//negative regulation of glucose transport;GO:0043393//regulation of protein binding;GO:0043627//response to estrogen;GO:0009967//positive regulation of signal transduction;GO:0009411//response to UV;GO:0010383;GO:0010243//response to organonitrogen compound;GO:0000723//telomere maintenance;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0019048//modulation by virus of host morphology or physiology;GO:0042493//response to drug;GO:0051604//protein maturation;GO:0006119//oxidative phosphorylation;GO:0044093;GO:0009698//phenylpropanoid metabolic process;GO:0006096//glycolytic process" gi|12851275|dbj|BAB28992.1|/3.22946e-94/unnamed protein product [Mus musculus] 320486 2487 0.363333333 0.58 0.674759171 Up 0.256205574 A430078I02Rik RIKEN cDNA A430078I02 gene - - - - - 229512 4447 17.48666667 18.89333333 0.111621951 Up 0.256045733 Smg5 "Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)" K11125|1|0.0|1720|mmu:229512|protein SMG5 - - - gi|37360236|dbj|BAC98096.1|/0/mKIAA1089 protein [Mus musculus] 21938 4913 3.926666667 3.433333333 -0.193695202 Down 0.256045733 Tnfrsf1b "tumor necrosis factor receptor superfamily, member 1b" K05141|1|0.0|835|mmu:21938|tumor necrosis factor receptor superfamily member 1B GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0031224//intrinsic component of membrane;GO:0033267;GO:0044444//cytoplasmic part GO:0044389//ubiquitin-like protein ligase binding;GO:0005035//death receptor activity GO:0070848//response to growth factor;GO:0032496//response to lipopolysaccharide;GO:0043487//regulation of RNA stability;GO:0019221//cytokine-mediated signaling pathway;GO:0006509//membrane protein ectodomain proteolysis;GO:0006954//inflammatory response;GO:0002376//immune system process gi|70778792|ref|NP_035740.2|/0/tumor necrosis factor receptor superfamily member 1B precursor [Mus musculus] 72754 4426.16 18.42 19.82666667 0.106169085 Up 0.256045733 Arhgef10l Rho guanine nucleotide exchange factor (GEF) 10-like K16727|1|0.0|2214|mmu:72754|Rho guanine nucleotide exchange factor 10 GO:0044444//cytoplasmic part GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0032233//positive regulation of actin filament bundle assembly;GO:0006984//ER-nucleus signaling pathway gi|163310755|ref|NP_001106193.1|/0/rho guanine nucleotide exchange factor 10-like protein isoform b [Mus musculus] 69773 3170 30.13333333 32.29 0.099727169 Up 0.256045733 1810026J23Rik RIKEN cDNA 1810026J23 gene - - - - - 232236 1757 3.943333333 3.453333333 -0.191426071 Down 0.256045733 Ccdc174 coiled-coil domain containing 174 - - - - gi|147899958|ref|NP_766318.2|/0/coiled-coil domain-containing protein 174 [Mus musculus] 21770 2926 30.89666667 33.05333333 0.097344572 Up 0.256045733 Ppp2r5d "protein phosphatase 2, regulatory subunit B', delta" K11584|1|0.0|1172|rno:363193|serine/threonine-protein phosphatase 2A regulatory subunit B' - GO:0005488//binding GO:0070848//response to growth factor;GO:0006366//transcription from RNA polymerase II promoter;GO:0010975//regulation of neuron projection development;GO:0001932//regulation of protein phosphorylation;GO:0009967//positive regulation of signal transduction gi|564311217|ref|XP_001065844.4|/0/PREDICTED: serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform X2 [Rattus norvegicus] 66412 3903 3.976666667 3.486666667 -0.189711191 Down 0.256045733 Arrdc4 arrestin domain containing 4 "K09364|1|8e-06|53.9|gja:107122555|POU domain transcription factor, class 2" - - - - 66194 1353 9.22 10.09333333 0.130564049 Up 0.256026928 Pycrl pyrroline-5-carboxylate reductase-like K00286|1|2e-152|541|mmu:66194|pyrroline-5-carboxylate reductase [EC:1.5.1.2] - "GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0005515//protein binding;GO:0036094//small molecule binding" GO:0006216//cytidine catabolic process;GO:0006561//proline biosynthetic process gi|119508439|ref|NP_079688.2|/1.7794e-151/pyrroline-5-carboxylate reductase 3 [Mus musculus] 70769 3659.84 10.39333333 9.523333333 -0.126119892 Down 0.256026928 Nolc1 nucleolar and coiled-body phosphoprotein 1 K11294|1|1e-31|141|spu:591574|nucleolin GO:0005654//nucleoplasm;GO:0005654//nucleoplasm;GO:0005654//nucleoplasm;GO:0005654//nucleoplasm GO:0005515//protein binding;GO:0030515//snoRNA binding;GO:0005048//signal sequence binding;GO:0005515//protein binding;GO:0030515//snoRNA binding;GO:0005048//signal sequence binding;GO:0005515//protein binding;GO:0030515//snoRNA binding;GO:0005048//signal sequence binding;GO:0005515//protein binding;GO:0030515//snoRNA binding;GO:0005048//signal sequence binding "GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0016074//snoRNA metabolic process;GO:0006950//response to stress;GO:0006606//protein import into nucleus;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0016074//snoRNA metabolic process;GO:0006950//response to stress;GO:0006606//protein import into nucleus;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0016074//snoRNA metabolic process;GO:0006950//response to stress;GO:0006606//protein import into nucleus;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0016074//snoRNA metabolic process;GO:0006950//response to stress;GO:0006606//protein import into nucleus" gi|86198329|ref|NP_001034441.1|/5.954e-98/nucleolar and coiled-body phosphoprotein 1 isoform C [Mus musculus] 72047 4028 10.34333333 9.476666667 -0.126249598 Down 0.256026928 Ddx42 DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 K12835|1|0.0|1592|mmu:72047|ATP-dependent RNA helicase DDX42 [EC:3.6.4.13] - - - "gi|148702333|gb|EDL34280.1|/0/DEAD (Asp-Glu-Ala-Asp) box polypeptide 42, isoform CRA_b, partial [Mus musculus]" 66406 1374 4.496666667 5.053333333 0.168379405 Up 0.256017526 Sac3d1 SAC3 domain containing 1 K16734|1|0.0|680|mmu:66406|SAC3 domain-containing protein 1 GO:0005815//microtubule organizing center - GO:0006461//protein complex assembly;GO:0007098//centrosome cycle;GO:0000087//mitotic M phase gi|119508435|ref|NP_598439.3|/0/SAC3 domain-containing protein 1 [Mus musculus] 54667 5459 4.956666667 4.4 -0.171866718 Down 0.256017526 Atp8b2 "ATPase, class I, type 8B, member 2" K01530|1|0.0|2207|mmu:54667|phospholipid-translocating ATPase [EC:3.6.3.1] - - - "gi|148683232|gb|EDL15179.1|/0/mCG22242, partial [Mus musculus]" 67939 2048.86 4.526666667 5.09 0.169216583 Up 0.256017526 Prorsd1 prolyl-tRNA synthetase domain containing 1 K10591|1|5e-07|58.9|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26];K09228|2|3e-06|56.6|rno:102551340|KRAB domain-containing zinc finger protein - GO:0052689//carboxylic ester hydrolase activity;GO:0052689//carboxylic ester hydrolase activity - gi|157822527|ref|NP_001099492.1|/5.49613e-76/prdX-deacylase domain-containing protein 1 [Rattus norvegicus] 17319 554 156.3333333 165.92 0.085862377 Up 0.256008124 Mif macrophage migration inhibitory factor K07253|1|4e-62|239|mmu:17319|phenylpyruvate tautomerase [EC:5.3.2.1] GO:0043231//intracellular membrane-bounded organelle;GO:0044421 "GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds;GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups;GO:0005102//receptor binding" "GO:0034614//cellular response to reactive oxygen species;GO:0010737//protein kinase A signaling;GO:0001934//positive regulation of protein phosphorylation;GO:0002720//positive regulation of cytokine production involved in immune response;GO:1901654//response to ketone;GO:0002237//response to molecule of bacterial origin;GO:0031103//axon regeneration;GO:0007050//cell cycle arrest;GO:0031324//negative regulation of cellular metabolic process;GO:0043434//response to peptide hormone;GO:0043066//negative regulation of apoptotic process;GO:0006935//chemotaxis;GO:0008284//positive regulation of cell proliferation;GO:0002526//acute inflammatory response;GO:0032305//positive regulation of icosanoid secretion;GO:0043436;GO:0048232//male gamete generation;GO:0007417//central nervous system development;GO:0030888//regulation of B cell proliferation;GO:0031960//response to corticosteroid;GO:0010467//gene expression;GO:0002833;GO:0001666//response to hypoxia;GO:0010828//positive regulation of glucose transport;GO:0007568//aging;GO:0050663//cytokine secretion;GO:0032722//positive regulation of chemokine production;GO:0001976//neurological system process involved in regulation of systemic arterial blood pressure;GO:0008544//epidermis development;GO:0043627//response to estrogen;GO:0002901;GO:0006813//potassium ion transport;GO:0051260//protein homooligomerization;GO:0043410//positive regulation of MAPK cascade;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0007631//feeding behavior;GO:0002250//adaptive immune response;GO:0043405//regulation of MAP kinase activity;GO:0014909//smooth muscle cell migration;GO:0006096//glycolytic process" gi|6754696|ref|NP_034928.1|/2.49689e-61/macrophage migration inhibitory factor [Mus musculus] 230810 3313 0.503333333 0.296666667 -0.762671308 Down 0.255998721 Slc30a2 "solute carrier family 30 (zinc transporter), member 2" "K14689|1|0.0|705|mmu:230810|solute carrier family 30 (zinc transporter), member 2" GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0031090//organelle membrane GO:0015075//ion transmembrane transporter activity GO:0006829//zinc II ion transport;GO:0032119//sequestering of zinc ion gi|89179312|ref|NP_001034766.1|/0/zinc transporter 2 [Mus musculus] 20215 1718 0.203333333 0.053333333 -1.930737338 Down 0.255951709 Sag "S-antigen, retina and pineal gland (arrestin)" K19627|1|0.0|733|mmu:20215|S-arrestin GO:0044464 GO:0005515//protein binding GO:0007154//cell communication;GO:0050953//sensory perception of light stimulus "gi|148708195|gb|EDL40142.1|/0/retinal S-antigen, isoform CRA_d, partial [Mus musculus]" 320183 3723 30.70666667 28.55333333 -0.104892734 Down 0.255942307 Msrb3 methionine sulfoxide reductase B3 K07305|1|3e-107|392|rno:680036|peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor" GO:0044267//cellular protein metabolic process;GO:0044710 "gi|327478524|sp|Q8BU85.2|MSRB3_MOUSE/2.61773e-125/RecName: Full=Methionine-R-sulfoxide reductase B3, mitochondrial; Short=MsrB3; Flags: Precursor" 330460 2824 0.44 0.243333333 -0.85456956 Down 0.255923502 Tmem150b transmembrane protein 150B K08796|1|3e-26|123|myd:102761344|BR serine/threonine kinase [EC:2.7.11.1] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|29244506|ref|NP_808555.1|/3.10026e-67/transmembrane protein 150B isoform 2 precursor [Mus musculus] 66432 1525 5.143333333 5.75 0.1608583 Up 0.255885893 Slc7a6os "solute carrier family 7, member 6 opposite strand" - GO:0043231//intracellular membrane-bounded organelle - GO:0045184//establishment of protein localization "gi|148679408|gb|EDL11355.1|/1.84433e-139/solute carrier family 7, member 6 opposite strand, isoform CRA_b [Mus musculus]" 19271 7553.22 1.52 1.86 0.291231298 Up 0.255848283 Ptprj "protein tyrosine phosphatase, receptor type, J" K05698|1|0.0|2460|mmu:19271|receptor-type tyrosine-protein phosphatase eta [EC:3.1.3.48] GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0044459;GO:0001726//ruffle;GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0044459;GO:0001726//ruffle GO:0019901//protein kinase binding;GO:0004721//phosphoprotein phosphatase activity;GO:0070851//growth factor receptor binding;GO:0019901//protein kinase binding;GO:0004721//phosphoprotein phosphatase activity;GO:0070851//growth factor receptor binding GO:0010543//regulation of platelet activation;GO:0043405//regulation of MAP kinase activity;GO:0006470//protein dephosphorylation;GO:0016049//cell growth;GO:0010469//regulation of receptor activity;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0043114//regulation of vascular permeability;GO:0050852//T cell receptor signaling pathway;GO:0008283//cell proliferation;GO:0044767//single-organism developmental process;GO:0001954//positive regulation of cell-matrix adhesion;GO:0010543//regulation of platelet activation;GO:0043405//regulation of MAP kinase activity;GO:0006470//protein dephosphorylation;GO:0016049//cell growth;GO:0010469//regulation of receptor activity;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0043114//regulation of vascular permeability;GO:0050852//T cell receptor signaling pathway;GO:0008283//cell proliferation;GO:0044767//single-organism developmental process;GO:0001954//positive regulation of cell-matrix adhesion gi|208609939|ref|NP_033008.3|/0/receptor-type tyrosine-protein phosphatase eta isoform 1 [Mus musculus] 66396 4665 29.45333333 31.59 0.101037019 Up 0.255848283 Ccdc82 coiled-coil domain containing 82 - - - - gi|61098118|ref|NP_079810.2|/0/coiled-coil domain-containing protein 82 [Mus musculus] 14020 5849 1.84 1.5 -0.294743266 Down 0.255848283 Evi5 ecotropic viral integration site 5 K20242|1|0.0|1461|mmu:14020|ecotropic viral integration site 5 protein GO:0044464 - - gi|111185905|ref|NP_031990.2|/0/ecotropic viral integration site 5 protein [Mus musculus] 11600 4316 1.833333333 1.496666667 -0.292716174 Down 0.255848283 Angpt1 angiopoietin 1 K05465|1|0.0|998|mmu:11600|angiopoietin 1 GO:0042995//cell projection;GO:0044425;GO:0044421;GO:0042995//cell projection;GO:0044425;GO:0044421 GO:0005126//cytokine receptor binding;GO:0005126//cytokine receptor binding GO:0001935//endothelial cell proliferation;GO:0003157//endocardium development;GO:0009888//tissue development;GO:0048534//hematopoietic or lymphoid organ development;GO:0010595//positive regulation of endothelial cell migration;GO:0043009//chordate embryonic development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016567//protein ubiquitination;GO:0006024//glycosaminoglycan biosynthetic process;GO:0043410//positive regulation of MAPK cascade;GO:0014841//skeletal muscle satellite cell proliferation;GO:0001934//positive regulation of protein phosphorylation;GO:0006935//chemotaxis;GO:0007599//hemostasis;GO:0003007//heart morphogenesis;GO:0001570//vasculogenesis;GO:0043114//regulation of vascular permeability;GO:0048545//response to steroid hormone;GO:0007155//cell adhesion;GO:0002090//regulation of receptor internalization;GO:0008585//female gonad development;GO:0001525//angiogenesis;GO:0033273//response to vitamin;GO:0051259//protein oligomerization;GO:0034613//cellular protein localization;GO:0006950//response to stress;GO:0043066//negative regulation of apoptotic process;GO:0001935//endothelial cell proliferation;GO:0003157//endocardium development;GO:0009888//tissue development;GO:0048534//hematopoietic or lymphoid organ development;GO:0010595//positive regulation of endothelial cell migration;GO:0043009//chordate embryonic development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016567//protein ubiquitination;GO:0006024//glycosaminoglycan biosynthetic process;GO:0043410//positive regulation of MAPK cascade;GO:0014841//skeletal muscle satellite cell proliferation;GO:0001934//positive regulation of protein phosphorylation;GO:0006935//chemotaxis;GO:0007599//hemostasis;GO:0003007//heart morphogenesis;GO:0001570//vasculogenesis;GO:0043114//regulation of vascular permeability;GO:0048545//response to steroid hormone;GO:0007155//cell adhesion;GO:0002090//regulation of receptor internalization;GO:0008585//female gonad development;GO:0001525//angiogenesis;GO:0033273//response to vitamin;GO:0051259//protein oligomerization;GO:0034613//cellular protein localization;GO:0006950//response to stress;GO:0043066//negative regulation of apoptotic process gi|50510321|dbj|BAD32146.1|/0/mKIAA0003 protein [Mus musculus] 209212 2647 1.526666667 1.87 0.292653173 Up 0.255848283 Osgin2 oxidative stress induced growth inhibitor family member 2 - - - - gi|227496929|ref|NP_666062.3|/0/oxidative stress-induced growth inhibitor 2 [Mus musculus] 23994 1860 135.8733333 145.0466667 0.094254802 Up 0.255820076 Dazap2 DAZ associated protein 2 - - - - gi|731456586|ref|XP_010594975.1|/5.07549e-83/PREDICTED: DAZ-associated protein 2 isoform X2 [Loxodonta africana] 72818 1597 0.206666667 0.056666667 -1.866733469 Down 0.255697845 2810471M01Rik RIKEN cDNA 2810471M01 gene - - - - - 317677 2662 0.086666667 0.25 1.528378972 Up 0.255641431 C1s2 "complement component 1, s subcomponent 2" "K01331|1|0.0|1386|mmu:317677|complement component 1, s subcomponent [EC:3.4.21.42]" GO:0031012//extracellular matrix GO:0004175//endopeptidase activity;GO:0046872//metal ion binding;GO:0005515//protein binding GO:0006952//defense response;GO:0046683//response to organophosphorus;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0019538//protein metabolic process;GO:0030154//cell differentiation gi|295444820|ref|NP_776289.2|/0/complement C1s-B subcomponent precursor [Mus musculus] 54383 2580.05 28.06 30.17666667 0.104918445 Up 0.255603821 Phc2 polyhomeotic-like 2 (Drosophila) K11457|1|0.0|1249|mmu:54383|polyhomeotic-like protein 2 GO:0031519//PcG protein complex;GO:0031981//nuclear lumen;GO:0031519//PcG protein complex;GO:0031981//nuclear lumen;GO:0031519//PcG protein complex;GO:0031981//nuclear lumen GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0048232//male gamete generation;GO:0048232//male gamete generation;GO:0032502//developmental process;GO:0048232//male gamete generation gi|9055280|ref|NP_061244.1|/0/polyhomeotic-like protein 2 isoform A [Mus musculus] 13999 428 2.97 2.546666667 -0.221852793 Down 0.255575614 Gm14288 predicted gene 14288 K09228|1|9e-30|130|mmu:664987|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|755502181|ref|XP_011248138.1|/3.84703e-42/PREDICTED: zinc finger protein 431-like [Mus musculus] 60455 3480 3.026666667 2.603333333 -0.217369749 Down 0.255575614 Tmem8 transmembrane protein 8 (five membrane-spanning domains) - GO:0016021//integral component of membrane - GO:0022610 gi|11140833|ref|NP_068565.1|/0/transmembrane protein 8A precursor [Mus musculus] 56077 5208 2.53 2.946666667 0.219946484 Up 0.255575614 Dgke "diacylglycerol kinase, epsilon" K00901|1|0.0|1166|mmu:56077|diacylglycerol kinase (ATP) [EC:2.7.1.107] GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0016301//kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0007186//G-protein coupled receptor signaling pathway gi|9506541|ref|NP_062378.1|/0/diacylglycerol kinase epsilon [Mus musculus] 67769 4565 2.99 2.573333333 -0.216507138 Down 0.255575614 Gpatch2 G patch domain containing 2 K17569|1|0.0|904|mmu:67769|G patch domain-containing protein 2 - - - "gi|148681100|gb|EDL13047.1|/0/G patch domain containing 2, isoform CRA_c, partial [Mus musculus]" 94332 4159 1.17 0.886666667 -0.400044785 Down 0.255556809 Cadm3 cell adhesion molecule 3 K06780|1|0.0|692|mmu:94332|cell adhesion molecule 3 GO:0030054//cell junction;GO:0031224//intrinsic component of membrane GO:0042802//identical protein binding GO:0016337//single organismal cell-cell adhesion;GO:0045216//cell-cell junction organization;GO:0033036;GO:0022607//cellular component assembly gi|16716503|ref|NP_444429.1|/0/cell adhesion molecule 3 precursor [Mus musculus] 108075 5121.68 141.7766667 133.0966667 -0.091145676 Down 0.2555192 Ltbp4 latent transforming growth factor beta binding protein 4 K08023|1|0.0|3084|mmu:108075|latent transforming growth factor beta binding protein 2/3/4 - - - gi|893569303|ref|NP_001297607.1|/0/latent-transforming growth factor beta-binding protein 4 isoform 3 precursor [Mus musculus] 57279 1783 140.6333333 149.2466667 0.085760123 Up 0.255490993 Slc25a20 "solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20" "K15109|1|4e-175|617|mmu:57279|solute carrier family 25 (mitochondrial carnitine/acylcarnitine transporter), member 20/29" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane - GO:0003333//amino acid transmembrane transport;GO:0019217//regulation of fatty acid metabolic process gi|10048462|ref|NP_065266.1|/3.70099e-174/mitochondrial carnitine/acylcarnitine carrier protein [Mus musculus] 240756 3281 6.86 6.203333333 -0.145164927 Down 0.255490993 Klhl12 kelch-like 12 K10450|1|0.0|1056|cfr:102504613|kelch-like protein 12 GO:0030133//transport vesicle;GO:0031461//cullin-RING ubiquitin ligase complex - GO:0006901//vesicle coating;GO:0016567//protein ubiquitination;GO:0007166//cell surface receptor signaling pathway;GO:0016482//cytosolic transport "gi|148707661|gb|EDL39608.1|/0/kelch-like 12 (Drosophila), isoform CRA_b, partial [Mus musculus]" 18022 1474 0.136666667 0.306666667 1.166009951 Up 0.25548159 Nfe2 "nuclear factor, erythroid derived 2" K09039|1|0.0|672|mmu:18022|nuclear factor erythroid 2 GO:0005856//cytoskeleton;GO:0016604//nuclear body;GO:0005856//cytoskeleton;GO:0016604//nuclear body;GO:0005856//cytoskeleton;GO:0016604//nuclear body;GO:0005856//cytoskeleton;GO:0016604//nuclear body;GO:0005856//cytoskeleton;GO:0016604//nuclear body GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0019904//protein domain specific binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0019904//protein domain specific binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0019904//protein domain specific binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0019904//protein domain specific binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0019904//protein domain specific binding "GO:0030279//negative regulation of ossification;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0030279//negative regulation of ossification;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0030279//negative regulation of ossification;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0030279//negative regulation of ossification;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0030279//negative regulation of ossification;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication" "gi|148671981|gb|EDL03928.1|/0/nuclear factor, erythroid derived 2, isoform CRA_a, partial [Mus musculus]" 217069 5596 10.03 9.17 -0.129327967 Down 0.25548159 Trim25 tripartite motif-containing 25 K10652|1|0.0|1283|mmu:217069|tripartite motif-containing protein 25 [EC:2.3.2.27] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0019787//ubiquitin-like protein transferase activity "GO:0006952//defense response;GO:0048545//response to steroid hormone;GO:0001818//negative regulation of cytokine production;GO:0002252;GO:0006351//transcription, DNA-templated" gi|145207948|ref|NP_033572.2|/0/E3 ubiquitin/ISG15 ligase TRIM25 [Mus musculus] 208146 6024 1.406666667 1.106666667 -0.346059757 Down 0.255443981 Yeats2 YEATS domain containing 2 K11341|1|3e-16|91.7|bfo:BRAFLDRAFT_113729|YEATS domain-containing protein 4 - - - "gi|148665144|gb|EDK97560.1|/0/mCG128458, partial [Mus musculus]" 70683 8831 1.366666667 1.07 -0.353050612 Down 0.255443981 Utp20 UTP20 small subunit processome component K14772|1|0.0|5008|mmu:70683|U3 small nucleolar RNA-associated protein 20 - - - gi|226437674|ref|NP_780367.2|/0/small subunit processome component 20 homolog [Mus musculus] 77675 1730 0.2 0.39 0.963474124 Up 0.255415773 5033406O09Rik RIKEN cDNA 5033406O09 gene - - - - gi|148686660|gb|EDL18607.1|/8.00884e-17/mCG147626 [Mus musculus] 107701 1741 17.8 19.18 0.107725479 Up 0.255368762 Sf3b4 "splicing factor 3b, subunit 4" K12831|1|2e-124|449|ngi:103742657|splicing factor 3B subunit 4 GO:0005681//spliceosomal complex GO:0036094//small molecule binding;GO:0003676//nucleic acid binding GO:0006396//RNA processing gi|674069743|ref|XP_008841952.1|/1.28988e-123/PREDICTED: splicing factor 3B subunit 4 [Nannospalax galili] 74158 3394 13.35666667 12.31666667 -0.116948145 Down 0.255349957 Josd1 Josephin domain containing 1 K15235|1|1e-109|400|mmu:74158|josephin [EC:3.4.19.12] - GO:0008238//exopeptidase activity GO:0019538//protein metabolic process gi|21311941|ref|NP_083068.1|/9.01639e-109/josephin-1 [Mus musculus] 246738 3373.39 11.53333333 12.57 0.124175113 Up 0.255349957 Dnajc28 DnaJ heat shock protein family (Hsp40) member C28 K19373|1|0.0|744|mmu:246738|DnaJ homolog subfamily C member 28 - - - - 70573 2830 2.826666667 3.263333333 0.207244595 Up 0.255293542 Tbccd1 TBCC domain containing 1 K16810|1|0.0|1028|mmu:70573|TBCC domain-containing protein 1 - - - - 665775 10443.59 2.803333333 3.24 0.208850513 Up 0.255293542 Bod1l biorientation of chromosomes in cell division 1-like K17582|1|9e-25|120|nvi:100120806|antigen KI-67;K12875|5|9e-13|79.3|crg:105337759|apoptotic chromatin condensation inducer in the nucleus - - - gi|124487265|ref|NP_001074891.1|/0/biorientation of chromosomes in cell division protein 1-like 1 isoform 1 [Mus musculus] 22341 1881 2.86 3.303333333 0.20790741 Up 0.255293542 Vegfc vascular endothelial growth factor C K05449|1|0.0|868|mmu:22341|vascular endothelial growth factor C/D GO:0044421 GO:0005172//vascular endothelial growth factor receptor binding GO:0001934//positive regulation of protein phosphorylation;GO:0001525//angiogenesis;GO:0051094//positive regulation of developmental process;GO:0050927//positive regulation of positive chemotaxis;GO:0009306//protein secretion;GO:0007405//neuroblast proliferation;GO:0002551//mast cell chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0002009//morphogenesis of an epithelium;GO:0009966//regulation of signal transduction;GO:0010595//positive regulation of endothelial cell migration;GO:0008217//regulation of blood pressure gi|6678565|ref|NP_033532.1|/0/vascular endothelial growth factor C precursor [Mus musculus] 16468 5801.02 3.236666667 2.796666667 -0.210800485 Down 0.255293542 Jarid2 "jumonji, AT rich interactive domain 2" K11478|1|0.0|2312|mmu:16468|protein Jumonji GO:0034708;GO:0031519//PcG protein complex;GO:0034708;GO:0031519//PcG protein complex;GO:0034708;GO:0031519//PcG protein complex GO:0003676//nucleic acid binding;GO:0032451//demethylase activity;GO:0003676//nucleic acid binding;GO:0032451//demethylase activity;GO:0003676//nucleic acid binding;GO:0032451//demethylase activity "GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0031062//positive regulation of histone methylation;GO:0048534//hematopoietic or lymphoid organ development;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0031062//positive regulation of histone methylation;GO:0048534//hematopoietic or lymphoid organ development;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0031062//positive regulation of histone methylation;GO:0048534//hematopoietic or lymphoid organ development;GO:0030154//cell differentiation" "gi|148709062|gb|EDL41008.1|/0/jumonji, AT rich interactive domain 2, isoform CRA_b, partial [Mus musculus]" 270162 2605 0.06 0.213333333 1.830074999 Up 0.255293542 Elmod1 ELMO/CED-12 domain containing 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0008047//enzyme activator activity GO:0043087//regulation of GTPase activity;GO:0006897//endocytosis gi|74205490|dbj|BAE21051.1|/0/unnamed protein product [Mus musculus] 26931 3849.76 30.83333333 28.74333333 -0.101263486 Down 0.255255933 Ppp2r5c "protein phosphatase 2, regulatory subunit B', gamma" K11584|1|0.0|984|mmu:26931|serine/threonine-protein phosphatase 2A regulatory subunit B' GO:0008287//protein serine/threonine phosphatase complex;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0008287//protein serine/threonine phosphatase complex;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0008287//protein serine/threonine phosphatase complex GO:0019888//protein phosphatase regulator activity;GO:0005488//binding;GO:0019888//protein phosphatase regulator activity;GO:0016787//hydrolase activity;GO:0019888//protein phosphatase regulator activity;GO:0005488//binding;GO:0019888//protein phosphatase regulator activity;GO:0016787//hydrolase activity "GO:0007154//cell communication;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0051604//protein maturation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0008283//cell proliferation;GO:0007154//cell communication;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0051604//protein maturation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0008283//cell proliferation" gi|125346154|ref|NP_001074927.1|/0/serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform c [Mus musculus] 18027 9528 7.296666667 8.033333333 0.138761192 Up 0.255246531 Nfia nuclear factor I/A K09168|1|0.0|767|chx:102189452|nuclear factor I/A GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding GO:0010033//response to organic substance;GO:0006366//transcription from RNA polymerase II promoter;GO:0019058//viral life cycle;GO:0010033//response to organic substance;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter "gi|148698959|gb|EDL30906.1|/0/nuclear factor I/A, isoform CRA_b, partial [Mus musculus]" 111175 1205 7.21 7.953333333 0.141560378 Up 0.255246531 Pecr peroxisomal trans-2-enoyl-CoA reductase K07753|1|7e-162|572|mmu:111175|peroxisomal trans-2-enoyl-CoA reductase [EC:1.3.1.38] GO:0044439 "GO:0005515//protein binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor" GO:0006631//fatty acid metabolic process;GO:0034308 gi|227908837|ref|NP_076012.3|/6.08965e-161/peroxisomal trans-2-enoyl-CoA reductase [Mus musculus] 66515 5546 8.243333333 7.5 -0.136337238 Down 0.255246531 Cul7 cullin 7 K10613|1|0.0|2989|mmu:66515|cullin 7 GO:0000151//ubiquitin ligase complex GO:0044389//ubiquitin-like protein ligase binding GO:0019941//modification-dependent protein catabolic process;GO:0030856//regulation of epithelial cell differentiation;GO:0006915//apoptotic process gi|57013279|ref|NP_079887.3|/0/cullin-7 [Mus musculus] 18477 1417 129.5333333 137.66 0.087786015 Up 0.255199519 Prdx1 peroxiredoxin 1 K13279|1|2e-113|412|mmu:18477|peroxiredoxin 1 [EC:1.11.1.15] GO:0048770;GO:0000790//nuclear chromatin;GO:0044439;GO:0044429 "GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0004601//peroxidase activity;GO:0042802//identical protein binding;GO:0046906//tetrapyrrole binding" GO:0048731//system development;GO:0042743//hydrogen peroxide metabolic process;GO:0043408//regulation of MAPK cascade;GO:0042348//NF-kappaB import into nucleus;GO:0044710;GO:0048872//homeostasis of number of cells;GO:0006801//superoxide metabolic process;GO:0006950//response to stress;GO:0001909//leukocyte mediated cytotoxicity gi|880893112|ref|XP_012970458.1|/3.49706e-113/PREDICTED: peroxiredoxin-1 [Mesocricetus auratus] 57435 5755 130.27 138.36 0.086922036 Up 0.255152507 Plin4 perilipin 4 K20254|1|0.0|2563|mmu:57435|perilipin-4 - - - gi|157041252|ref|NP_065593.2|/0/perilipin-4 [Mus musculus] 68703 7458 18.66666667 17.29666667 -0.109970291 Down 0.2551243 Rere arginine glutamic acid dipeptide (RE) repeats K05628|1|0.0|1147|mmu:68703|arginine-glutamic acid dipeptide repeats protein GO:0031981//nuclear lumen GO:0005488//binding GO:0009987//cellular process;GO:0044699 gi|148682942|gb|EDL14889.1|/0/mCG130721 [Mus musculus] 244058 3586 16.56666667 17.93666667 0.114628455 Up 0.2551243 Rgma repulsive guidance molecule family member A K06847|1|0.0|743|mmu:244058|RGM domain family GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0038023//signaling receptor activity;GO:0005488//binding GO:0014020;GO:0001932//regulation of protein phosphorylation;GO:0030509//BMP signaling pathway "gi|148675189|gb|EDL07136.1|/0/RGM domain family, member A, isoform CRA_b, partial [Mus musculus]" 73229 4367 0.203333333 0.393333333 0.951905712 Up 0.255077288 3110052M02Rik zinc finger protein 983 K09228|1|0.0|881|rno:499056|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding - "gi|148673789|gb|EDL05736.1|/0/mCG140664, isoform CRA_a, partial [Mus musculus]" 279572 4014 0.716666667 0.976666667 0.446564005 Up 0.255030276 Tlr13 toll-like receptor 13 K18808|1|0.0|1920|mmu:279572|toll-like receptor 13 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding;GO:0042802//identical protein binding GO:0051707//response to other organism;GO:0002224//toll-like receptor signaling pathway;GO:0000165//MAPK cascade gi|45429999|ref|NP_991389.1|/0/toll-like receptor 13 precursor [Mus musculus] 70511 2140 12.32 13.34666667 0.115477217 Up 0.254945654 Eef2kmt eukaryotic elongation factor 2 lysine methyltransferase "K12354|1|4e-126|454|aml:100474730|ectonucleotide pyrophosphatase/phosphodiesterase family member 7 [EC:3.1.4.12];K03842|2|6e-31|138|mmu:208211|beta-1,4-mannosyltransferase [EC:2.4.1.142]" - - - gi|74315977|ref|NP_081722.1|/0/protein-lysine N-methyltransferase EEF2KMT [Mus musculus] 211586 7350.85 17.87333333 19.23 0.105550044 Up 0.254926849 Tfdp2 transcription factor Dp 2 K09392|1|5e-179|632|cge:100759949|transcription factor Dp-2 GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0012505//endomembrane system "GO:0000989//transcription factor activity, transcription factor binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding" "GO:0044767//single-organism developmental process;GO:0051318;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0044763;GO:0044767//single-organism developmental process;GO:0006351//transcription, DNA-templated;GO:0044763;GO:0044767//single-organism developmental process;GO:0006351//transcription, DNA-templated" gi|568961058|ref|XP_006511025.1|/0/PREDICTED: transcription factor Dp-2 isoform X4 [Mus musculus] 100017 2671 9.163333333 10.01333333 0.127977906 Up 0.254823423 Ldlrap1 low density lipoprotein receptor adaptor protein 1 K12474|1|4e-165|584|mmu:100017|low density lipoprotein receptor adapter protein 1 - - - - 217517 4325 1.843333333 2.206666667 0.259551737 Up 0.254795216 Stxbp6 syntaxin binding protein 6 (amisyn) K08519|1|1e-117|427|nle:100604961|syntaxin-binding protein 6 GO:0044424;GO:0031224//intrinsic component of membrane - GO:0006810//transport gi|803317004|ref|XP_012016728.1|/3.49586e-125/PREDICTED: syntaxin-binding protein 6 isoform X4 [Ovis aries musimon] 214899 10969 2.156666667 1.8 -0.260806305 Down 0.254795216 Kdm5a lysine (K)-specific demethylase 5A K11446|1|0.0|2971|mmu:214899|histone demethylase JARID1 [EC:1.14.11.-] GO:0043234//protein complex;GO:0031981//nuclear lumen "GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0001071//nucleic acid binding transcription factor activity" "GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization;GO:0032502//developmental process" gi|226958545|ref|NP_666109.2|/0/lysine-specific demethylase 5A [Mus musculus] 104625 5529.12 2.16 1.8 -0.263034406 Down 0.254795216 Cnot6 "CCR4-NOT transcription complex, subunit 6" K12603|1|0.0|1050|xla:100505426|CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity "GO:0044093;GO:0006351//transcription, DNA-templated;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0044093;GO:0006351//transcription, DNA-templated;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" gi|62078445|ref|NP_001013878.1|/0/CCR4-NOT transcription complex subunit 6 [Rattus norvegicus] 22658 2347 4.24 4.786666667 0.174957079 Up 0.254748204 Pcgf2 polycomb group ring finger 2 K11460|1|1e-157|531|oas:101120343|polycomb group RING finger protein 2 GO:0000785//chromatin;GO:0044451;GO:0031519//PcG protein complex;GO:0000803//sex chromosome;GO:0000785//chromatin;GO:0044451;GO:0031519//PcG protein complex;GO:0000803//sex chromosome;GO:0000785//chromatin;GO:0044451;GO:0031519//PcG protein complex;GO:0000803//sex chromosome GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0019787//ubiquitin-like protein transferase activity GO:0001501//skeletal system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0016570//histone modification;GO:0048562//embryonic organ morphogenesis;GO:0006915//apoptotic process;GO:0043009//chordate embryonic development;GO:0003002//regionalization;GO:0001501//skeletal system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0016570//histone modification;GO:0048562//embryonic organ morphogenesis;GO:0006915//apoptotic process;GO:0043009//chordate embryonic development;GO:0003002//regionalization;GO:0001501//skeletal system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0016570//histone modification;GO:0048562//embryonic organ morphogenesis;GO:0006915//apoptotic process;GO:0043009//chordate embryonic development;GO:0003002//regionalization gi|803120721|ref|XP_012041395.1|/3.21764e-159/PREDICTED: polycomb group RING finger protein 2 isoform X3 [Ovis aries] 17827 1522 17.36 18.71 0.108042611 Up 0.254748204 Mtx1 metaxin 1 K17776|1|0.0|791|mmu:17827|metaxin GO:0019866//organelle inner membrane;GO:0031966//mitochondrial membrane;GO:0019866//organelle inner membrane;GO:0031966//mitochondrial membrane - - gi|241982740|ref|NP_038632.2|/0/metaxin-1 isoform 1 [Mus musculus] 68980 1230.44 5.703333333 5.103333333 -0.160365477 Down 0.254663583 Wdr53 WD repeat domain 53 K18643|1|6e-10|68.2|umr:103673887|katanin p80 WD40 repeat-containing subunit B1;K16482|2|9e-10|67.4|dre:386932|centriolar protein POC1 - - - gi|568996126|ref|XP_006522572.1|/0/PREDICTED: WD repeat-containing protein 53 isoform X2 [Mus musculus] 66387 786 113.7933333 121.19 0.090854621 Up 0.25465418 Nudt8 nudix (nucleoside diphosphate linked moiety X)-type motif 8 K18665|1|4e-97|356|mmu:66387|nudix motif 8 [EC:3.6.1.-] - - - - 68512 654.23 121.2333333 113.8533333 -0.090609895 Down 0.254635376 Tomm5 translocase of outer mitochondrial membrane 5 homolog (yeast) K17773|1|2e-20|101|rno:680080|mitochondrial import receptor subunit TOM5 GO:0031224//intrinsic component of membrane;GO:0005741//mitochondrial outer membrane;GO:0031224//intrinsic component of membrane;GO:0005741//mitochondrial outer membrane GO:0022892//substrate-specific transporter activity;GO:0022892//substrate-specific transporter activity GO:0006605//protein targeting;GO:0019538//protein metabolic process;GO:0006605//protein targeting;GO:0019538//protein metabolic process gi|672019283|ref|XP_003754060.2|/1.26464e-19/PREDICTED: mitochondrial import receptor subunit TOM5 homolog [Rattus norvegicus] 17762 5005.64 27.76666667 29.79333333 0.101635549 Up 0.254597766 Mapt microtubule-associated protein tau K04380|1|4e-158|562|rno:29477|microtubule-associated protein tau GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0030426//growth cone;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0005930//axoneme;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0030426//growth cone;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0005930//axoneme;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0030426//growth cone;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0005930//axoneme;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0030426//growth cone;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0005930//axoneme;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0030426//growth cone;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0005930//axoneme;GO:0044444//cytoplasmic part GO:0071814;GO:0019904//protein domain specific binding;GO:0015631//tubulin binding;GO:0019900//kinase binding;GO:0071814;GO:0019904//protein domain specific binding;GO:0015631//tubulin binding;GO:0019900//kinase binding;GO:0071814;GO:0019904//protein domain specific binding;GO:0015631//tubulin binding;GO:0019900//kinase binding;GO:0071814;GO:0019904//protein domain specific binding;GO:0015631//tubulin binding;GO:0019900//kinase binding;GO:0071814;GO:0019904//protein domain specific binding;GO:0015631//tubulin binding;GO:0019900//kinase binding "GO:0030307//positive regulation of cell growth;GO:0042221//response to chemical;GO:0012501//programmed cell death;GO:0010970//transport along microtubule;GO:0007409//axonogenesis;GO:0031112;GO:0034643//establishment of mitochondrion localization, microtubule-mediated;GO:0006914//autophagy;GO:0032386//regulation of intracellular transport;GO:0016477//cell migration;GO:0031667//response to nutrient levels;GO:0008344//adult locomotory behavior;GO:0030307//positive regulation of cell growth;GO:0042221//response to chemical;GO:0012501//programmed cell death;GO:0010970//transport along microtubule;GO:0007409//axonogenesis;GO:0031112;GO:0034643//establishment of mitochondrion localization, microtubule-mediated;GO:0006914//autophagy;GO:0032386//regulation of intracellular transport;GO:0016477//cell migration;GO:0031667//response to nutrient levels;GO:0008344//adult locomotory behavior;GO:0030307//positive regulation of cell growth;GO:0042221//response to chemical;GO:0012501//programmed cell death;GO:0010970//transport along microtubule;GO:0007409//axonogenesis;GO:0031112;GO:0034643//establishment of mitochondrion localization, microtubule-mediated;GO:0006914//autophagy;GO:0032386//regulation of intracellular transport;GO:0016477//cell migration;GO:0031667//response to nutrient levels;GO:0008344//adult locomotory behavior;GO:0030307//positive regulation of cell growth;GO:0042221//response to chemical;GO:0012501//programmed cell death;GO:0010970//transport along microtubule;GO:0007409//axonogenesis;GO:0031112;GO:0034643//establishment of mitochondrion localization, microtubule-mediated;GO:0006914//autophagy;GO:0032386//regulation of intracellular transport;GO:0016477//cell migration;GO:0031667//response to nutrient levels;GO:0008344//adult locomotory behavior;GO:0030307//positive regulation of cell growth;GO:0042221//response to chemical;GO:0012501//programmed cell death;GO:0010970//transport along microtubule;GO:0007409//axonogenesis;GO:0031112;GO:0034643//establishment of mitochondrion localization, microtubule-mediated;GO:0006914//autophagy;GO:0032386//regulation of intracellular transport;GO:0016477//cell migration;GO:0031667//response to nutrient levels;GO:0008344//adult locomotory behavior" gi|550544199|ref|NP_001272384.1|/2.39197e-148/microtubule-associated protein tau isoform d [Mus musculus] 14218 10408.41 8.15 7.416666667 -0.136029129 Down 0.254588364 Sh3pxd2a SH3 and PX domains 2A K08011|1|6e-55|220|ocu:100008803|neutrophil cytosolic factor 1 - - - gi|181336814|ref|NP_032044.2|/0/SH3 and PX domain-containing protein 2A isoform 1 [Mus musculus] 56094 2493 0.31 0.14 -1.146841388 Down 0.254503742 Cts8 cathepsin 8 K01365|1|1e-149|533|cge:100772033|cathepsin L [EC:3.4.22.15];K09600|2|7e-129|464|mmu:64139|cathepsin M [EC:3.4.22.-];K09601|4|2e-120|436|rno:498688|cathepsin R [EC:3.4.22.-];K09599|5|4e-117|425|rno:29174|cathepsin P [EC:3.4.22.-] GO:0000323//lytic vacuole "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process gi|187960088|ref|NP_062414.3|/0/cathepsin 8 precursor [Mus musculus] 75180 1504 0.136666667 0.303333333 1.150242636 Up 0.254503742 4930538K18Rik RIKEN cDNA 4930538K18 gene - - - - gi|58037399|ref|NP_083474.1|/4.03109e-147/uncharacterized protein LOC75180 [Mus musculus] 16650 5711 18.39333333 17.05666667 -0.108847223 Down 0.254475535 Kpna6 karyopherin (importin) alpha 6 K15042|1|0.0|788|clv:102088810|importin subunit alpha-1 GO:0043231//intracellular membrane-bounded organelle GO:0022892//substrate-specific transporter activity GO:0007565//female pregnancy;GO:0006886//intracellular protein transport;GO:0006366//transcription from RNA polymerase II promoter gi|227116300|ref|NP_032494.3|/0/importin subunit alpha-7 [Mus musculus] 60611 5013 17.76333333 16.42666667 -0.112862577 Down 0.254475535 Foxj2 forkhead box J2 K09403|1|0.0|911|mmu:60611|forkhead box protein J2/3 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|521023772|gb|EPQ05560.1|/0/Forkhead box protein J2 [Myotis brandtii] 26611 2042 17.70333333 19.04333333 0.105265 Up 0.254475535 Rcn2 reticulocalbin 2 - GO:0044432;GO:0044432 GO:0046872//metal ion binding;GO:0046872//metal ion binding - gi|74146742|dbj|BAE41353.1|/0/unnamed protein product [Mus musculus] 23983 1711 109.1233333 116.2166667 0.090857362 Up 0.254447328 Pcbp1 poly(rC) binding protein 1 K12889|1|0.0|711|rro:104663122|poly(rC)-binding protein 1 GO:0032991//macromolecular complex;GO:0031981//nuclear lumen "GO:0090079//translation regulator activity, nucleic acid binding;GO:0043566//structure-specific DNA binding" GO:0006412//translation;GO:0000377 gi|724828135|ref|XP_010362558.1|/0/PREDICTED: poly(rC)-binding protein 1 [Rhinopithecus roxellana] 76311 1498 0.9 1.183333333 0.394859617 Up 0.254447328 1110019D14Rik RIKEN cDNA 1110019D14 gene - - - - - 21761 1906 113.69 120.7766667 0.087236399 Up 0.254447328 Morf4l1 mortality factor 4 like 1 K11339|1|0.0|663|ecb:100059897|mortality factor 4-like protein 1 GO:0070822//Sin3-type complex;GO:0043189//H4/H2A histone acetyltransferase complex;GO:0070822//Sin3-type complex;GO:0043189//H4/H2A histone acetyltransferase complex GO:0005515//protein binding;GO:0005515//protein binding "GO:0006476//protein deacetylation;GO:0040007//growth;GO:0000725//recombinational repair;GO:0006351//transcription, DNA-templated;GO:0016573//histone acetylation;GO:0006476//protein deacetylation;GO:0040007//growth;GO:0000725//recombinational repair;GO:0006351//transcription, DNA-templated;GO:0016573//histone acetylation" gi|85540473|ref|NP_001034236.1|/0/mortality factor 4-like protein 1 isoform a [Mus musculus] 13382 2291 119.19 112.1366667 -0.088005109 Down 0.254428523 Dld dihydrolipoamide dehydrogenase K00382|1|0.0|1015|mmu:13382|dihydrolipoamide dehydrogenase [EC:1.8.1.4] GO:0031981//nuclear lumen;GO:0001669//acrosomal vesicle;GO:0043234//protein complex;GO:0044429 "GO:0000166//nucleotide binding;GO:0033218//amide binding;GO:0016668//oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor" GO:0043648//dicarboxylic acid metabolic process;GO:0003006//developmental process involved in reproduction;GO:0006790//sulfur compound metabolic process;GO:0006873//cellular ion homeostasis;GO:0006085//acetyl-CoA biosynthetic process;GO:0048598//embryonic morphogenesis;GO:0022904//respiratory electron transport chain;GO:0019538//protein metabolic process "gi|148704970|gb|EDL36917.1|/0/dihydrolipoamide dehydrogenase, partial [Mus musculus]" 19299 3399 29.35 31.37 0.096025026 Up 0.254409718 Abcd3 "ATP-binding cassette, sub-family D (ALD), member 3" "K05677|1|0.0|1279|mmu:19299|ATP-binding cassette, subfamily D (ALD), member 3" GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0044439 GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0015405;GO:0042802//identical protein binding GO:0042221//response to chemical;GO:0000038//very long-chain fatty acid metabolic process;GO:0015909//long-chain fatty acid transport;GO:0009062//fatty acid catabolic process;GO:0006996//organelle organization;GO:0009154//purine ribonucleotide catabolic process "gi|148680385|gb|EDL12332.1|/0/ATP-binding cassette, sub-family D (ALD), member 3, isoform CRA_b, partial [Mus musculus]" 12856 436 108.82 115.7733333 0.089359255 Up 0.254372109 Cox17 cytochrome c oxidase assembly protein 17 K02260|1|2e-18|93.2|shr:100919403|cytochrome c oxidase assembly protein subunit 17 GO:0005740//mitochondrial envelope GO:0005507//copper ion binding GO:0007417//central nervous system development;GO:0044237//cellular metabolic process;GO:0000041//transition metal ion transport;GO:0044767//single-organism developmental process gi|744568968|ref|XP_010979873.1|/5.02198e-18/PREDICTED: cytochrome c oxidase copper chaperone [Camelus dromedarius] 67035 2548.66 30.85 28.84 -0.097199325 Down 0.254315694 Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 K09510|1|0.0|651|mmu:67035|DnaJ homolog subfamily B member 4 - - - - 19862 107 103.0833333 109.9466667 0.092992771 Up 0.254306292 Rnu6 U6 small nuclear RNA K05692|1|9e-11|67.4|pps:103784606|actin beta/gamma 1;K07023|3|2e-06|52.8|aml:100470328|putative hydrolases of HD superfamily - - - gi|537152882|gb|ERE72362.1|/5.27797e-12/membralin-like protein [Cricetulus griseus] 66148 671 116.3766667 109.5933333 -0.086641789 Down 0.254212268 Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 K09535|1|5e-65|249|mmu:66148|DnaJ homolog subfamily C member 15 - - - - 140482 1999 30.4 28.40333333 -0.098011073 Down 0.254193463 Zfp358 zinc finger protein 358 K09228|1|1e-150|535|bom:102286069|KRAB domain-containing zinc finger protein GO:0044464 GO:0046914//transition metal ion binding - gi|148689962|gb|EDL21909.1|/0/zinc finger protein 358 [Mus musculus] 56736 3092.68 30.9 28.90333333 -0.096370954 Down 0.254193463 Rnf14 ring finger protein 14 K11971|1|0.0|893|mmu:56736|E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0016881//acid-amino acid ligase activity;GO:0035258//steroid hormone receptor binding;GO:0046914//transition metal ion binding;GO:0016881//acid-amino acid ligase activity;GO:0035258//steroid hormone receptor binding;GO:0046914//transition metal ion binding;GO:0016881//acid-amino acid ligase activity;GO:0035258//steroid hormone receptor binding "GO:0043627//response to estrogen;GO:0006351//transcription, DNA-templated;GO:0030521//androgen receptor signaling pathway;GO:0043627//response to estrogen;GO:0006351//transcription, DNA-templated;GO:0030521//androgen receptor signaling pathway;GO:0043627//response to estrogen;GO:0006351//transcription, DNA-templated;GO:0030521//androgen receptor signaling pathway" "gi|148678143|gb|EDL10090.1|/0/ring finger protein 14, isoform CRA_f [Mus musculus]" 104009 2861.57 28.93 30.93333333 0.096595981 Up 0.254193463 Qsox1 quiescin Q6 sulfhydryl oxidase 1 K10758|1|0.0|1077|mmu:104009|thiol oxidase [EC:1.8.3.2] GO:0031228//intrinsic component of Golgi membrane;GO:0044421;GO:0031228//intrinsic component of Golgi membrane;GO:0044421 GO:0016972//thiol oxidase activity;GO:0016972//thiol oxidase activity GO:0044267//cellular protein metabolic process;GO:0044710;GO:0019725//cellular homeostasis;GO:0044267//cellular protein metabolic process;GO:0044710;GO:0019725//cellular homeostasis "gi|148707454|gb|EDL39401.1|/0/quiescin Q6, isoform CRA_b, partial [Mus musculus]" 12398 7627.75 10.1 9.26 -0.125271194 Down 0.254090037 Cbfa2t3 "core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)" "K10053|1|0.0|812|cmk:103184601|runt-related transcription factor 1; translocated to, 1" GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0002573//myeloid leukocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0002573//myeloid leukocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0002573//myeloid leukocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter gi|568956027|ref|XP_006530683.1|/0/PREDICTED: protein CBFA2T3 isoform X4 [Mus musculus] 215031 1664 0.213333333 0.066666667 -1.678071905 Down 0.254052428 Vgll2 vestigial like family member 2 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding GO:0014706//striated muscle tissue development;GO:0006366//transcription from RNA polymerase II promoter;GO:0014706//striated muscle tissue development;GO:0006366//transcription from RNA polymerase II promoter "gi|148673124|gb|EDL05071.1|/1.63929e-144/vestigial like 2 homolog (Drosophila), isoform CRA_a, partial [Mus musculus]" 18645 2020 16.90666667 18.22666667 0.108458497 Up 0.254014818 Pfn2 profilin 2 K05759|1|1e-77|293|pale:102894047|profilin GO:0005856//cytoskeleton;GO:0033267 GO:0008092//cytoskeletal protein binding;GO:0043168//anion binding GO:0016079//synaptic vesicle exocytosis;GO:0030041//actin filament polymerization;GO:0008064//regulation of actin polymerization or depolymerization gi|918612024|ref|XP_005393063.2|/6.86579e-79/PREDICTED: profilin-2 [Chinchilla lanigera] 20280 2664 96.43 102.9833333 0.09485692 Up 0.254014818 Scp2 "sterol carrier protein 2, liver" K08764|1|0.0|1075|mmu:20280|sterol carrier protein 2 [EC:2.3.1.176] GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0044439 GO:0036041//long-chain fatty acid binding;GO:0005515//protein binding;GO:0005548//phospholipid transporter activity;GO:0032934//sterol binding;GO:0000062//fatty-acyl-CoA binding;GO:0016408//C-acyltransferase activity GO:0006732;GO:0006635//fatty acid beta-oxidation;GO:0006700//C21-steroid hormone biosynthetic process;GO:0001676//long-chain fatty acid metabolic process;GO:0007009//plasma membrane organization;GO:0032957//inositol trisphosphate metabolic process;GO:0006996//organelle organization;GO:0032367//intracellular cholesterol transport gi|45476581|ref|NP_035457.1|/0/non-specific lipid-transfer protein [Mus musculus] 16728 5288 0.996666667 0.733333333 -0.442641961 Down 0.253920794 L1cam L1 cell adhesion molecule K06550|1|0.0|2491|mmu:16728|L1 cell adhesion molecule GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0009986//cell surface;GO:0033267;GO:0097060//synaptic membrane GO:0005102//receptor binding;GO:0031406//carboxylic acid binding;GO:0019904//protein domain specific binding GO:0071363//cellular response to growth factor stimulus;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0016337//single organismal cell-cell adhesion;GO:0030030//cell projection organization;GO:0045471//response to ethanol;GO:0006935//chemotaxis;GO:0019722//calcium-mediated signaling gi|112293279|ref|NP_032504.3|/0/neural cell adhesion molecule L1 precursor [Mus musculus] 214585 7665 3.783333333 4.293333333 0.182440296 Up 0.25390199 Spg11 spastic paraplegia 11 K19026|1|0.0|4598|mmu:214585|spatacsin GO:0031982//vesicle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen GO:0005488//binding - gi|226958532|ref|NP_663506.2|/0/spatacsin [Mus musculus] 20399 3111.09 28.18333333 30.15666667 0.097634717 Up 0.253817368 Sh2b1 SH2B adaptor protein 1 K12459|1|0.0|573|mmu:20399|SH2B adaptor protein 1/3 GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007067//mitotic nuclear division;GO:0051052//regulation of DNA metabolic process;GO:0030031//cell projection assembly;GO:0007067//mitotic nuclear division;GO:0051052//regulation of DNA metabolic process;GO:0030031//cell projection assembly;GO:0007067//mitotic nuclear division;GO:0051052//regulation of DNA metabolic process;GO:0030031//cell projection assembly;GO:0007067//mitotic nuclear division;GO:0051052//regulation of DNA metabolic process;GO:0030031//cell projection assembly;GO:0007067//mitotic nuclear division;GO:0051052//regulation of DNA metabolic process;GO:0030031//cell projection assembly;GO:0007067//mitotic nuclear division;GO:0051052//regulation of DNA metabolic process;GO:0030031//cell projection assembly;GO:0007067//mitotic nuclear division;GO:0051052//regulation of DNA metabolic process;GO:0030031//cell projection assembly;GO:0007067//mitotic nuclear division;GO:0051052//regulation of DNA metabolic process;GO:0030031//cell projection assembly "gi|148685424|gb|EDL17371.1|/0/SH2B adaptor protein 1, isoform CRA_i, partial [Mus musculus]" 11758 2392.15 102.43 108.7733333 0.086686594 Up 0.253760954 Prdx6 peroxiredoxin 6 "K11188|1|2e-121|439|mmu:11758|peroxiredoxin 6, 1-Cys peroxiredoxin [EC:1.11.1.7 1.11.1.15 3.1.1.-]" GO:0000323//lytic vacuole;GO:0031982//vesicle;GO:0000323//lytic vacuole;GO:0031982//vesicle;GO:0000323//lytic vacuole;GO:0031982//vesicle "GO:0005488//binding;GO:0004620//phospholipase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0004601//peroxidase activity;GO:0005488//binding;GO:0004620//phospholipase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0004601//peroxidase activity;GO:0005488//binding;GO:0004620//phospholipase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0004601//peroxidase activity" GO:0006979//response to oxidative stress;GO:0006644//phospholipid metabolic process;GO:0042743//hydrogen peroxide metabolic process;GO:0030031//cell projection assembly;GO:0006644//phospholipid metabolic process;GO:0042743//hydrogen peroxide metabolic process;GO:0006950//response to stress;GO:0030031//cell projection assembly;GO:0006979//response to oxidative stress;GO:0006644//phospholipid metabolic process;GO:0042743//hydrogen peroxide metabolic process;GO:0030031//cell projection assembly gi|6671549|ref|NP_031479.1|/1.59461e-120/peroxiredoxin-6 isoform 1 [Mus musculus] 11610 4038.66 16.25 17.56333333 0.112126961 Up 0.253751551 Agtrap "angiotensin II, type I receptor-associated protein" - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0012506//vesicle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0012506//vesicle membrane GO:0005488//binding;GO:0001595//angiotensin receptor activity;GO:0005488//binding;GO:0001595//angiotensin receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0008015//blood circulation;GO:0006950//response to stress;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008015//blood circulation;GO:0006950//response to stress gi|31542119|ref|NP_033772.2|/3.72432e-77/type-1 angiotensin II receptor-associated protein isoform 1 [Mus musculus] 13595 1757 7.26 7.98 0.136419198 Up 0.253713942 Ebp phenylalkylamine Ca2+ antagonist (emopamil) binding protein K01824|1|2e-132|475|mmu:13595|cholestenol Delta-isomerase [EC:5.3.3.5] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds" GO:0006694//steroid biosynthetic process;GO:0048534//hematopoietic or lymphoid organ development;GO:0008203//cholesterol metabolic process "gi|6681255|ref|NP_031924.1|/1.30481e-131/3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase [Mus musculus]" 75855 1516 0.07 0.22 1.652076697 Up 0.253713942 4930579H20Rik RIKEN cDNA 4930579H20 gene - - - - - 277432 1381 0.18 0.036666667 -2.295455884 Down 0.25366693 Vstm2l V-set and transmembrane domain containing 2-like K03538|1|6e-12|74.7|tgu:100231396|ribonuclease P protein subunit POP4 [EC:3.1.26.5] GO:0031224//intrinsic component of membrane - - "gi|148674300|gb|EDL06247.1|/8.04746e-91/gene model 691, (NCBI), partial [Mus musculus]" 56874 1338 0.036666667 0.173333333 2.2410081 Up 0.25366693 Rnf32 ring finger protein 32 - GO:0016234//inclusion body;GO:0016234//inclusion body;GO:0016234//inclusion body GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - gi|153792209|ref|NP_067445.3|/0/RING finger protein 32 [Mus musculus] 71840 1532 0.32 0.146666667 -1.125530882 Down 0.253601113 Tekt4 tektin 4 K18631|1|0.0|875|mmu:71840|tektin-4 GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton - GO:0007010//cytoskeleton organization gi|110625871|ref|NP_082227.1|/0/tektin-4 [Mus musculus] 67978 2735 1.906666667 2.273333333 0.253756592 Up 0.253591711 Tctn2 tectonic family member 2 K19361|1|0.0|1305|mmu:67978|tectonic-2 GO:0005815//microtubule organizing center;GO:0031224//intrinsic component of membrane;GO:0035869//ciliary transition zone;GO:0033176//proton-transporting V-type ATPase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity "GO:0048858//cell projection morphogenesis;GO:0010927;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0007166//cell surface receptor signaling pathway" gi|13385970|ref|NP_080762.1|/0/tectonic-2 precursor [Mus musculus] 216829 1883 1.99 2.363333333 0.248054696 Up 0.253591711 Mmgt2 membrane magnesium transporter 2 K18163|1|2e-11|73.6|loa:LOAG_08427|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 6;K12163|2|4e-06|55.8|aqu:100638471|AN1-type zinc finger and ubiquitin domain-containing protein 1 GO:0005769//early endosome;GO:0031224//intrinsic component of membrane GO:0022890//inorganic cation transmembrane transporter activity;GO:0046873//metal ion transmembrane transporter activity GO:0006825//copper ion transport;GO:0070838//divalent metal ion transport;GO:0006828//manganese ion transport;GO:0015675//nickel cation transport gi|33239401|ref|NP_778167.1|/1.97376e-56/membrane magnesium transporter 2 precursor [Mus musculus] 76220 4308 2.323333333 1.95 -0.252722031 Down 0.253591711 6530402F18Rik RIKEN cDNA 6530402F18 gene K16359|1|9e-37|159|mmu:171171|netrin-G2 GO:0031225//anchored component of membrane - GO:0048667//cell morphogenesis involved in neuron differentiation "gi|148676466|gb|EDL08413.1|/5.8785e-76/mCG145104, partial [Mus musculus]" 81004 8127 4.203333333 4.743333333 0.174367386 Up 0.253582308 Tbl1xr1 transducin (beta)-like 1X-linked receptor 1 K04508|1|0.0|973|mmu:81004|transducin (beta)-like 1 GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0000975//regulatory region DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006325//chromatin organization gi|31543001|ref|NP_109657.2|/0/F-box-like/WD repeat-containing protein TBL1XR1 [Mus musculus] 68077 1572 101.9466667 108.1566667 0.08530799 Up 0.253572906 Gltscr2 glioma tumor suppressor candidate region gene 2 K14840|1|0.0|747|mmu:68077|nucleolar protein 53 GO:0031981//nuclear lumen - - gi|228480230|ref|NP_598592.2|/0/glioma tumor suppressor candidate region gene 2 protein [Mus musculus] 230848 7208 1.58 1.266666667 -0.318887641 Down 0.253554101 Zbtb40 zinc finger and BTB domain containing 40 K10512|1|0.0|2363|mmu:230848|zinc finger and BTB domain-containing protein 40 GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding GO:0033554//cellular response to stress gi|38016187|ref|NP_937891.1|/0/zinc finger and BTB domain-containing protein 40 [Mus musculus] 12777 1725 0.23 0.076666667 -1.584962501 Down 0.253554101 Ccr10 chemokine (C-C motif) receptor 10 K04185|1|1e-107|392|mmu:12777|C-C chemokine receptor type 10 GO:0016020//membrane GO:0004950//chemokine receptor activity;GO:0005488//binding GO:0019221//cytokine-mediated signaling pathway;GO:0051480//regulation of cytosolic calcium ion concentration gi|11024708|ref|NP_031747.2|/1.0843e-106/C-C chemokine receptor type 10 [Mus musculus] 21789 1522 0.396666667 0.21 -0.91753784 Down 0.253544699 Tfpi2 tissue factor pathway inhibitor 2 K03909|1|6e-35|151|hgl:101710461|tissue factor pathway inhibitor - GO:0004857//enzyme inhibitor activity GO:0007599//hemostasis;GO:0051346//negative regulation of hydrolase activity gi|568939536|ref|XP_006505106.1|/9.80219e-133/PREDICTED: tissue factor pathway inhibitor 2 isoform X2 [Mus musculus] 13664 2879 5.716666667 5.123333333 -0.158091411 Down 0.253525894 Eif1a eukaryotic translation initiation factor 1A K03236|1|3e-49|199|ngi:103727416|translation initiation factor 1A GO:0044444//cytoplasmic part "GO:0008135//translation factor activity, RNA binding" GO:0006412//translation gi|569003225|ref|XP_006525689.1|/9.14096e-99/PREDICTED: eukaryotic translation initiation factor 1A isoform X1 [Mus musculus] 66645 2375 5.506666667 4.92 -0.162520965 Down 0.253525894 Pspc1 paraspeckle protein 1 "K13214|1|1e-109|400|cmk:103178559|non-POU domain-containing octamer-binding protein;K13219|2|1e-107|393|mdo:100031251|splicing factor, proline- and glutamine-rich" GO:0016604//nuclear body GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|225543409|ref|NP_079958.3|/0/paraspeckle component 1 [Mus musculus] 100502698 5316 9.53 8.703333333 -0.130908162 Down 0.253497687 Rubcn "RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein" K19330|1|0.0|1509|mmu:100502698|run domain Beclin-1 interacting and cysteine-rich containing protein GO:0005768//endosome;GO:0000323//lytic vacuole;GO:0005768//endosome;GO:0000323//lytic vacuole - GO:0006897//endocytosis;GO:0006914//autophagy;GO:0006897//endocytosis;GO:0006914//autophagy gi|28972099|dbj|BAC65503.1|/0/mKIAA0226 protein [Mus musculus] 56334 2029 93.57666667 99.72 0.091734044 Up 0.253497687 Tmed2 transmembrane emp24 domain trafficking protein 2 K20347|1|1e-100|369|lve:103078052|p24 family protein beta-1 GO:0000139//Golgi membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0031224//intrinsic component of membrane;GO:0030667//secretory granule membrane;GO:0030137//COPI-coated vesicle GO:0005488//binding GO:0043087//regulation of GTPase activity;GO:0014020;GO:0010467//gene expression;GO:0040007//growth;GO:0006901//vesicle coating;GO:0016482//cytosolic transport;GO:0006612//protein targeting to membrane;GO:0035964//COPI-coated vesicle budding;GO:0001890//placenta development;GO:0003143//embryonic heart tube morphogenesis;GO:0000578//embryonic axis specification;GO:0009952//anterior/posterior pattern specification;GO:0001701//in utero embryonic development gi|947231308|ref|XP_014443550.1|/1.21043e-99/PREDICTED: transmembrane emp24 domain-containing protein 2 [Tupaia chinensis] 19859 215 0.1 0.26 1.378511623 Up 0.253488285 Rnu3b2 U3B small nuclear RNA 2 - - - - gi|296489304|tpg|DAA31417.1|/1.99513e-13/TPA: polypyrimidine tract binding protein 2-like [Bos taurus] 12616 2827 99.97 106.0766667 0.08554022 Up 0.253488285 Cenpb centromere protein B K11496|1|0.0|718|mmu:12616|centromere protein B - - - - 19858 215 0.1 0.26 1.378511623 Up 0.253488285 Rnu3b1 U3B small nuclear RNA 1 - - - - gi|296489304|tpg|DAA31417.1|/1.99513e-13/TPA: polypyrimidine tract binding protein 2-like [Bos taurus] 19860 215 0.1 0.26 1.378511623 Up 0.253488285 Rnu3b3 U3B small nuclear RNA 3 - - - - gi|296489304|tpg|DAA31417.1|/1.99513e-13/TPA: polypyrimidine tract binding protein 2-like [Bos taurus] 434128 4147 1.56 1.896666667 0.281920123 Up 0.25346948 Pnmal2 PNMA-like 2 K02183|1|2e-23|114|umr:103657204|calmodulin;K17561|2|2e-11|74.7|cge:103164277|coiled-coil domain-containing protein 8 - - - gi|153791731|ref|NP_001093106.1|/0/PNMA-like protein 2 [Mus musculus] 22371 8834 11.38333333 12.38666667 0.121864923 Up 0.253441273 Vwf Von Willebrand factor K03900|1|0.0|5814|mmu:22371|von Willebrand factor GO:0030141//secretory granule;GO:0009986//cell surface;GO:0031012//extracellular matrix GO:0032403//protein complex binding;GO:0042802//identical protein binding;GO:0019899//enzyme binding;GO:0005102//receptor binding GO:0050896//response to stimulus;GO:0009888//tissue development;GO:0001775//cell activation;GO:0051259//protein oligomerization;GO:0044767//single-organism developmental process;GO:0007155//cell adhesion;GO:0007599//hemostasis gi|568941437|ref|XP_006505980.1|/0/PREDICTED: von Willebrand factor isoform X1 [Mus musculus] 382030 1832 11.83666667 12.83666667 0.117007763 Up 0.253441273 Cnep1r1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 - GO:0031224//intrinsic component of membrane;GO:0008287//protein serine/threonine phosphatase complex;GO:0005635//nuclear envelope GO:0005488//binding GO:0006470//protein dephosphorylation;GO:0010866//regulation of triglyceride biosynthetic process;GO:0033365//protein localization to organelle gi|77735559|ref|NP_001029475.1|/2.39706e-67/nuclear envelope phosphatase-regulatory subunit 1 [Bos taurus] 19063 2493 26.76333333 28.70333333 0.100960475 Up 0.253413066 Ppt1 palmitoyl-protein thioesterase 1 K01074|1|8e-165|583|mmu:19063|palmitoyl-protein thioesterase [EC:3.1.2.22] GO:0043005//neuron projection;GO:0044297//cell body;GO:0000323//lytic vacuole;GO:0044425;GO:0044421;GO:0030136//clathrin-coated vesicle GO:0047617//acyl-CoA hydrolase activity "GO:0000737//DNA catabolic process, endonucleolytic;GO:0007626//locomotory behavior;GO:0007417//central nervous system development;GO:0043066//negative regulation of apoptotic process;GO:0006898//receptor-mediated endocytosis;GO:0006907//pinocytosis;GO:0007612//learning;GO:0006665//sphingolipid metabolic process;GO:0050953//sensory perception of light stimulus;GO:0035601//protein deacylation;GO:0045184//establishment of protein localization;GO:0030163//protein catabolic process;GO:0050804//modulation of synaptic transmission;GO:0001505//regulation of neurotransmitter levels;GO:0035751//regulation of lysosomal lumen pH;GO:0016049//cell growth;GO:0010517//regulation of phospholipase activity;GO:0030182//neuron differentiation" gi|121674797|ref|NP_032943.2|/6.84724e-164/palmitoyl-protein thioesterase 1 precursor [Mus musculus] 12387 3554.01 97.89333333 91.86666667 -0.091669132 Down 0.253403663 Ctnnb1 "catenin (cadherin associated protein), beta 1" K02105|1|0.0|1522|cge:100773307|catenin beta 1 - - - gi|6671684|ref|NP_031640.1|/0/catenin beta-1 [Mus musculus] 78733 2280 0.473333333 0.703333333 0.571352069 Up 0.253375456 Troap trophinin associated protein - GO:0044424;GO:0044424 - GO:0022610;GO:0022610 "gi|148672199|gb|EDL04146.1|/0/mCG18421, isoform CRA_b, partial [Mus musculus]" 408062 2300 0.69 0.463333333 -0.574545885 Down 0.253375456 Zfp873 zinc finger protein 873 K09228|1|0.0|915|mmu:666584|KRAB domain-containing zinc finger protein - - - gi|110665709|ref|NP_001019797.2|/0/zinc finger protein 873 isoform 2 [Mus musculus] 100503869 964 0.48 0.713333333 0.571541985 Up 0.253375456 Mkln1os "muskelin 1, intracellular mediator containing kelch motifs, opposite strand" - - - - - 237558 3114 0.663333333 0.916666667 0.466663188 Up 0.253347249 Myrfl myelin regulatory factor-like - GO:0031224//intrinsic component of membrane GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated" gi|74188453|dbj|BAE25858.1|/0/unnamed protein product [Mus musculus] 117592 3213 0.643333333 0.893333333 0.473632153 Up 0.253347249 B3galt6 "UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6" K00734|1|0.0|647|mmu:117592|galactosylxylosylprotein 3-beta-galactosyltransferase [EC:2.4.1.134] GO:0031985//Golgi cisterna;GO:0031224//intrinsic component of membrane GO:0035250//UDP-galactosyltransferase activity GO:0006464//cellular protein modification process;GO:0006023 "gi|17978260|ref|NP_536693.1|/0/beta-1,3-galactosyltransferase 6 [Mus musculus]" 378702 3077.4 91.36333333 97.28666667 0.090626807 Up 0.253281432 Serf2 small EDRK-rich factor 2 - - - - gi|655862992|ref|XP_008267307.1|/1.24097e-53/PREDICTED: small EDRK-rich factor 2 isoform X1 [Oryctolagus cuniculus] 20301 628.03 5.783333333 6.423333333 0.151420909 Up 0.253281432 Ccl27a chemokine (C-C motif) ligand 27A K16598|1|2e-43|178|mmu:100862247|C-C motif chemokine 27 - GO:0005125//cytokine activity;GO:0005125//cytokine activity;GO:0005488//binding;GO:0005488//binding GO:0002376//immune system process;GO:0002376//immune system process gi|884917344|ref|XP_013008960.1|/2.805e-46/PREDICTED: C-C motif chemokine 27 isoform X4 [Cavia porcellus] 14758 4330.14 3.226666667 2.796666667 -0.206336237 Down 0.25327203 Gpm6b glycoprotein m6b K17271|1|3e-77|293|xma:102228944|myelin proteolipid protein GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0048523//negative regulation of cellular process;GO:0022607//cellular component assembly;GO:0043271//negative regulation of ion transport;GO:0045184//establishment of protein localization;GO:0030036//actin cytoskeleton organization;GO:0030282//bone mineralization;GO:0001952//regulation of cell-matrix adhesion;GO:0048523//negative regulation of cellular process;GO:0022607//cellular component assembly;GO:0043271//negative regulation of ion transport;GO:0045184//establishment of protein localization;GO:0030036//actin cytoskeleton organization;GO:0030282//bone mineralization;GO:0001952//regulation of cell-matrix adhesion;GO:0048523//negative regulation of cellular process;GO:0022607//cellular component assembly;GO:0043271//negative regulation of ion transport;GO:0045184//establishment of protein localization;GO:0030036//actin cytoskeleton organization;GO:0030282//bone mineralization;GO:0001952//regulation of cell-matrix adhesion;GO:0048523//negative regulation of cellular process;GO:0022607//cellular component assembly;GO:0043271//negative regulation of ion transport;GO:0045184//establishment of protein localization;GO:0030036//actin cytoskeleton organization;GO:0030282//bone mineralization;GO:0001952//regulation of cell-matrix adhesion;GO:0048869//cellular developmental process;GO:0048523//negative regulation of cellular process;GO:0022607//cellular component assembly;GO:0043271//negative regulation of ion transport;GO:0045184//establishment of protein localization;GO:0030036//actin cytoskeleton organization;GO:0030282//bone mineralization;GO:0001952//regulation of cell-matrix adhesion;GO:0048869//cellular developmental process;GO:0048523//negative regulation of cellular process;GO:0022607//cellular component assembly;GO:0043271//negative regulation of ion transport;GO:0045184//establishment of protein localization;GO:0030036//actin cytoskeleton organization;GO:0030282//bone mineralization;GO:0001952//regulation of cell-matrix adhesion;GO:0048869//cellular developmental process;GO:0048523//negative regulation of cellular process;GO:0022607//cellular component assembly;GO:0043271//negative regulation of ion transport;GO:0045184//establishment of protein localization;GO:0030036//actin cytoskeleton organization;GO:0030282//bone mineralization;GO:0001952//regulation of cell-matrix adhesion;GO:0048869//cellular developmental process;GO:0048523//negative regulation of cellular process;GO:0022607//cellular component assembly;GO:0043271//negative regulation of ion transport;GO:0045184//establishment of protein localization;GO:0030036//actin cytoskeleton organization;GO:0030282//bone mineralization;GO:0001952//regulation of cell-matrix adhesion;GO:0048523//negative regulation of cellular process;GO:0022607//cellular component assembly;GO:0043271//negative regulation of ion transport;GO:0045184//establishment of protein localization;GO:0030036//actin cytoskeleton organization;GO:0030282//bone mineralization;GO:0001952//regulation of cell-matrix adhesion gi|295789070|ref|NP_001171427.1|/5.61652e-179/neuronal membrane glycoprotein M6-b isoform 2 [Mus musculus] 216131 5048 17.55 16.25666667 -0.110439559 Down 0.25327203 Trappc10 trafficking protein particle complex 10 K20307|1|0.0|2504|mmu:216131|trafficking protein particle complex subunit 10 GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046873//metal ion transmembrane transporter activity;GO:0005488//binding GO:0006814//sodium ion transport gi|124486684|ref|NP_001074524.1|/0/trafficking protein particle complex subunit 10 [Mus musculus] 66375 1318 16.68333333 17.97333333 0.107450427 Up 0.25327203 Dhrs7 dehydrogenase/reductase (SDR family) member 7 K11165|1|0.0|637|mmu:66375|dehydrogenase/reductase SDR family member 7 [EC:1.1.-.-] - - - "gi|148704579|gb|EDL36526.1|/0/dehydrogenase/reductase (SDR family) member 7, partial [Mus musculus]" 73729 2620 2.8 3.233333333 0.207595419 Up 0.25327203 Zfp383 zinc finger protein 383 K09228|1|0.0|1023|mmu:73729|KRAB domain-containing zinc finger protein - - - gi|345199298|ref|NP_001230837.1|/0/zinc finger protein 383 [Mus musculus] 675921 1392 0.176666667 0.04 -2.142957954 Down 0.25323442 Tnk2os "tyrosine kinase, non-receptor 2, opposite strand" K08886|1|7e-07|57.8|nle:100604750|activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1] - - - gi|74148839|dbj|BAE32130.1|/1.77093e-61/unnamed protein product [Mus musculus] 16525 2306 0.256666667 0.1 -1.359895945 Down 0.25323442 Kcnk1 "potassium channel, subfamily K, member 1" K04912|1|4e-148|528|mmu:16525|potassium channel subfamily K member 1 GO:0043231//intracellular membrane-bounded organelle;GO:0005903//brush border;GO:0005887//integral component of plasma membrane GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity GO:0007267//cell-cell signaling;GO:0014070//response to organic cyclic compound;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|160358858|ref|NP_032456.2|/3.11587e-147/potassium channel subfamily K member 1 [Mus musculus] 14693 1593 91.82333333 97.66333333 0.088956214 Up 0.253159201 Gnb2 "guanine nucleotide binding protein (G protein), beta 2" K04537|1|0.0|671|ecb:100067486|guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 - - - - 71939 2215.4 0.413333333 0.22 -0.909802191 Down 0.253149799 Apol6 apolipoprotein L 6 K14480|1|1e-127|459|mmu:71939|apolipoprotein L - - - gi|74190596|dbj|BAE25940.1|/3.9167e-162/unnamed protein product [Mus musculus] 50767 4472.61 3.513333333 3.06 -0.199308808 Down 0.253130994 Pnpla6 patatin-like phospholipase domain containing 6 K14676|1|0.0|2560|mmu:50767|lysophospholipid hydrolase [EC:3.1.1.5] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0004620//phospholipase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0004620//phospholipase activity;GO:0052689//carboxylic ester hydrolase activity GO:0009653//anatomical structure morphogenesis;GO:0006650//glycerophospholipid metabolic process;GO:0009653//anatomical structure morphogenesis;GO:0006650//glycerophospholipid metabolic process gi|568953379|ref|XP_006508888.1|/0/PREDICTED: neuropathy target esterase isoform X5 [Mus musculus] 12837 5110 3.51 3.056666667 -0.199511797 Down 0.253130994 Col8a1 "collagen, type VIII, alpha 1" "K19479|1|8e-45|186|ssc:448809|collagen, type X, alpha" - - - "gi|148665761|gb|EDK98177.1|/2.09667e-95/procollagen, type VIII, alpha 1, isoform CRA_b, partial [Mus musculus]" 105785 1414 3.08 3.526666667 0.195374871 Up 0.253130994 Kdelr3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 K10949|1|2e-109|398|mmu:105785|ER lumen protein retaining receptor GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0005048//signal sequence binding GO:0035437//maintenance of protein localization in endoplasmic reticulum;GO:0045184//establishment of protein localization;GO:0006810//transport gi|269914085|ref|NP_598851.2|/1.97966e-108/ER lumen protein-retaining receptor 3 [Mus musculus] 15930 1506 0.33 0.54 0.710493383 Up 0.253102787 Ido1 "indoleamine 2,3-dioxygenase 1" "K00463|1|0.0|759|mmu:15930|indoleamine 2,3-dioxygenase [EC:1.13.11.52]" GO:0043292//contractile fiber;GO:0043292//contractile fiber "GO:0031406//carboxylic acid binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0043169//cation binding;GO:0046906//tetrapyrrole binding;GO:0031406//carboxylic acid binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0043169//cation binding;GO:0046906//tetrapyrrole binding" GO:0018130;GO:0001818//negative regulation of cytokine production;GO:0042130//negative regulation of T cell proliferation;GO:0002517//T cell tolerance induction;GO:0001819//positive regulation of cytokine production;GO:0002544//chronic inflammatory response;GO:0070229//negative regulation of lymphocyte apoptotic process;GO:0006569//tryptophan catabolic process;GO:0002237//response to molecule of bacterial origin;GO:0002828//regulation of type 2 immune response;GO:0018130;GO:0001818//negative regulation of cytokine production;GO:0042130//negative regulation of T cell proliferation;GO:0002517//T cell tolerance induction;GO:0001819//positive regulation of cytokine production;GO:0002544//chronic inflammatory response;GO:0070229//negative regulation of lymphocyte apoptotic process;GO:0006569//tryptophan catabolic process;GO:0002237//response to molecule of bacterial origin;GO:0002828//regulation of type 2 immune response "gi|6680347|ref|NP_032350.1|/0/indoleamine 2,3-dioxygenase 1 isoform 1 [Mus musculus]" 244631 3317 11.20666667 12.2 0.122523924 Up 0.253018165 Pskh1 protein serine kinase H1 K08808|1|0.0|792|oas:101116671|protein serine kinase H [EC:2.7.11.1] GO:0015630//microtubule cytoskeleton;GO:0016604//nuclear body;GO:0031090//organelle membrane GO:0032550;GO:0004672//protein kinase activity GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process gi|537204681|gb|ERE79789.1|/0/serine/threonine-protein kinase H1 [Cricetulus griseus] 11983 1514 97.72 92.01 -0.086863196 Down 0.252980556 Atpif1 ATPase inhibitory factor 1 - GO:0005743//mitochondrial inner membrane GO:0042802//identical protein binding;GO:0019899//enzyme binding;GO:0004857//enzyme inhibitor activity GO:0043086//negative regulation of catalytic activity;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0001935//endothelial cell proliferation;GO:0006140;GO:0006915//apoptotic process;GO:0030099//myeloid cell differentiation;GO:0051260//protein homooligomerization "gi|31982864|ref|NP_031538.2|/4.46582e-53/ATPase inhibitor, mitochondrial precursor [Mus musculus]" 66612 2023 27.42333333 29.33 0.096973128 Up 0.252961751 Ormdl3 ORM1-like 3 (S. cerevisiae) K12667|1|5e-37|158|smm:Smp_144800|oligosaccharyltransferase complex subunit delta (ribophorin II) - - - - 218811 4385.53 29.30666667 27.39666667 -0.097228513 Down 0.252961751 Sec24c "Sec24 related gene family, member C (S. cerevisiae)" K14007|1|0.0|1907|rno:685144|protein transport protein SEC24 GO:0012507//ER to Golgi transport vesicle membrane;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding GO:0016482//cytosolic transport;GO:0015031//protein transport;GO:0045184//establishment of protein localization gi|28972055|dbj|BAC65481.1|/0/mKIAA0079 protein [Mus musculus] 76640 1343 0.183333333 0.043333333 -2.080919995 Down 0.252952349 1700113H08Rik RIKEN cDNA 1700113H08 gene - - - - gi|258613935|ref|NP_083961.1|/2.6085e-179/uncharacterized protein C12orf42 homolog [Mus musculus] 330385 995 0.92 1.2 0.38332864 Up 0.252895934 9530026P05Rik RIKEN cDNA 9530026P05 gene - - - - - 232164 3330 8.813333333 9.636666667 0.128846432 Up 0.252886532 Paip2b poly(A) binding protein interacting protein 2B - - GO:0003729//mRNA binding;GO:0030371//translation repressor activity GO:0006413//translational initiation gi|50510813|dbj|BAD32392.1|/4.55812e-81/mKIAA1155 protein [Mus musculus] 53376 3435.17 87.26 92.89333333 0.090254589 Up 0.252886532 Usp2 ubiquitin specific peptidase 2 K11833|1|0.0|1156|mmu:53376|ubiquitin carboxyl-terminal hydrolase 2/21 [EC:3.4.19.12] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0044389//ubiquitin-like protein ligase binding;GO:0016790//thiolester hydrolase activity;GO:0043169//cation binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0044389//ubiquitin-like protein ligase binding;GO:0016790//thiolester hydrolase activity;GO:0043169//cation binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0044389//ubiquitin-like protein ligase binding;GO:0016790//thiolester hydrolase activity;GO:0043169//cation binding" GO:0000278//mitotic cell cycle;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0007519//skeletal muscle tissue development;GO:0019941//modification-dependent protein catabolic process;GO:0070646//protein modification by small protein removal;GO:0000278//mitotic cell cycle;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0007519//skeletal muscle tissue development;GO:0019941//modification-dependent protein catabolic process;GO:0070646//protein modification by small protein removal;GO:0000278//mitotic cell cycle;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0007519//skeletal muscle tissue development;GO:0019941//modification-dependent protein catabolic process;GO:0070646//protein modification by small protein removal gi|114052498|ref|NP_932760.2|/0/ubiquitin carboxyl-terminal hydrolase 2 isoform Usp2-69 [Mus musculus] 67057 2264.89 8.906666667 9.73 0.127554203 Up 0.252886532 Yaf2 YY1 associated factor 2 K11468|1|9e-59|231|mmu:67057|YY1-associated factor 2 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0005488//binding;GO:0003712//transcription cofactor activity;GO:0005488//binding;GO:0003712//transcription cofactor activity "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|568993114|ref|XP_006521355.1|/1.59064e-64/PREDICTED: YY1-associated factor 2 isoform X1 [Mus musculus] 208117 4558 1.473333333 1.803333333 0.291582224 Up 0.252820715 Aph1b "aph1 homolog B, gamma secretase subunit" K06172|1|2e-121|440|mmu:208117|anterior pharynx defective 1 - - - - 226151 6880 1.476666667 1.803333333 0.288321895 Up 0.252820715 Fam178a "family with sequence similarity 178, member A" - - - - - 26557 10977.5 7.68 6.973333333 -0.139257865 Down 0.252811313 Homer2 homer scaffolding protein 2 K15010|1|0.0|663|mmu:26557|homer - - - - 100494 3183.91 7.146666667 7.853333333 0.136034633 Up 0.252811313 Zfand2a "zinc finger, AN1-type domain 2A" - GO:0044424;GO:0044424 GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - gi|19111158|ref|NP_579927.1|/1.34563e-90/AN1-type zinc finger protein 2A [Mus musculus] 19877 6187 3.756666667 3.29 -0.191365526 Down 0.252707887 Rock1 Rho-associated coiled-coil containing protein kinase 1 K04514|1|0.0|2555|mmu:19877|Rho-associated protein kinase 1 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0032550;GO:0004672//protein kinase activity;GO:0043169//cation binding;GO:0017048//Rho GTPase binding;GO:0008289//lipid binding GO:0001525//angiogenesis;GO:0007010//cytoskeleton organization;GO:0007265//Ras protein signal transduction;GO:0030029//actin filament-based process;GO:0043066//negative regulation of apoptotic process;GO:0003382//epithelial cell morphogenesis;GO:0006796//phosphate-containing compound metabolic process;GO:0022406//membrane docking;GO:0030031//cell projection assembly;GO:0006464//cellular protein modification process;GO:0007159//leukocyte cell-cell adhesion;GO:0002376//immune system process;GO:0030216//keratinocyte differentiation "gi|537229522|gb|ERE83867.1|/0/rho-associated protein kinase 1, partial [Cricetulus griseus]" 72465 3196.5 3.783333333 3.316666667 -0.189923867 Down 0.252707887 Zfp131 zinc finger protein 131 K10500|1|3e-38|163|pss:102446629|zinc finger and BTB domain-containing protein 17 - - - - 382074 1666 0.68 0.933333333 0.456857675 Up 0.25244462 Foxr1 forkhead box R1 - - - - gi|85701638|ref|NP_001028641.1|/9.7013e-121/forkhead box protein R1 [Mus musculus] 68285 2687 0.326666667 0.153333333 -1.091147888 Down 0.252397608 C630043F03Rik RIKEN cDNA C630043F03 gene - - - - gi|149059558|gb|EDM10496.1|/4.41735e-07/rCG55251 [Rattus norvegicus] 16796 3433 27.11 25.25 -0.102541725 Down 0.252369401 Lasp1 LIM and SH3 protein 1 K18267|1|3e-49|200|xma:102236960|nebulin GO:0005924//cell-substrate adherens junction;GO:0044444//cytoplasmic part;GO:0015629//actin cytoskeleton "GO:0022891//substrate-specific transmembrane transporter activity;GO:0046914//transition metal ion binding;GO:0030674//protein binding, bridging;GO:0003779//actin binding" GO:0006811//ion transport gi|6754508|ref|NP_034818.1|/4.04381e-141/LIM and SH3 domain protein 1 [Mus musculus] 50912 2801.37 27.1 28.95666667 0.095602685 Up 0.252369401 Exosc10 exosome component 10 K12591|1|0.0|1597|mmu:50912|exosome complex exonuclease RRP6 [EC:3.1.13.-] - - - - 76499 5558.14 8.616666667 9.426666667 0.12961784 Up 0.252265975 Clasp2 CLIP associating protein 2 K16578|1|2e-55|219|hsa:23122|CLIP-associating protein 1/2 "GO:0043231//intracellular membrane-bounded organelle;GO:0001726//ruffle;GO:0005874//microtubule;GO:0000775//chromosome, centromeric region;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0001726//ruffle;GO:0005874//microtubule;GO:0000775//chromosome, centromeric region;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0001726//ruffle;GO:0005874//microtubule;GO:0000775//chromosome, centromeric region;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0001726//ruffle;GO:0005874//microtubule;GO:0000775//chromosome, centromeric region;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0001726//ruffle;GO:0005874//microtubule;GO:0000775//chromosome, centromeric region;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0001726//ruffle;GO:0005874//microtubule;GO:0000775//chromosome, centromeric region;GO:0044444//cytoplasmic part;GO:0016020//membrane" GO:0008017//microtubule binding;GO:0008017//microtubule binding;GO:0008017//microtubule binding;GO:0008017//microtubule binding;GO:0008017//microtubule binding;GO:0008017//microtubule binding GO:0007019//microtubule depolymerization;GO:0048870//cell motility;GO:0000087//mitotic M phase;GO:0007019//microtubule depolymerization;GO:0048870//cell motility;GO:0000087//mitotic M phase;GO:0007019//microtubule depolymerization;GO:0048870//cell motility;GO:0000087//mitotic M phase;GO:0007019//microtubule depolymerization;GO:0048870//cell motility;GO:0000087//mitotic M phase;GO:0007019//microtubule depolymerization;GO:0048870//cell motility;GO:0000087//mitotic M phase;GO:0007019//microtubule depolymerization;GO:0048870//cell motility;GO:0000087//mitotic M phase gi|557636644|ref|NP_001273529.1|/0/CLIP-associating protein 2 isoform e [Mus musculus] 102182 2781 5.413333333 4.83 -0.164494038 Down 0.25224717 Prmt9 protein arginine methyltransferase 9 K19737|1|0.0|1666|mmu:102182|type II protein arginine methyltransferase [EC:2.1.1.320] - - - - 71198 2529 6.56 5.926666667 -0.146474897 Down 0.252237767 Otud1 OTU domain containing 1 K13716|1|9e-172|606|mmu:71198|OTU domain-containing protein 1 [EC:3.4.19.12] - - - gi|259906433|ref|NP_081991.1|/7.69758e-171/OTU domain-containing protein 1 [Mus musculus] 69537 1635 5.78 6.41 0.149254864 Up 0.252237767 Dnase1l1 deoxyribonuclease 1-like 1 K11995|1|4e-152|540|mmu:69537|deoxyribonuclease-1-like protein [EC:3.1.21.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004520//endodeoxyribonuclease activity;GO:0004520//endodeoxyribonuclease activity GO:0006259//DNA metabolic process;GO:0006259//DNA metabolic process "gi|148697887|gb|EDL29834.1|/6.93736e-155/deoxyribonuclease 1-like 1, isoform CRA_b, partial [Mus musculus]" 71742 2826 4.326666667 3.83 -0.175911585 Down 0.25220956 Ulk3 unc-51-like kinase 3 K08269|1|0.0|866|mmu:71742|serine/threonine-protein kinase ULK/ATG1 [EC:2.7.11.1] GO:0044444//cytoplasmic part GO:0032550;GO:0004672//protein kinase activity GO:0007224//smoothened signaling pathway;GO:0044248;GO:0006468//protein phosphorylation;GO:0007569//cell aging gi|242332525|ref|NP_082171.1|/0/serine/threonine-protein kinase ULK3 [Mus musculus] 26561 1433.24 4.313333333 3.813333333 -0.177750565 Down 0.25220956 Mmp23 matrix metallopeptidase 23 K08001|1|0.0|734|mmu:26561|matrix metalloproteinase-23 (CA-MMP) [EC:3.4.24.-] GO:0031012//extracellular matrix;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031012//extracellular matrix;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0019538//protein metabolic process;GO:0019538//protein metabolic process gi|6754710|ref|NP_036115.1|/0/matrix metalloproteinase-23 isoform 1 precursor [Mus musculus] 665574 3833 3.84 4.336666667 0.175480245 Up 0.25220956 Gm7694 predicted gene 7694 K16513|1|7e-97|358|pon:100448244|carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein - - - gi|755495856|ref|XP_011237156.1|/2.13293e-138/PREDICTED: uncharacterized protein C1orf226 homolog isoform X1 [Mus musculus] 75985 2007 2.66 2.273333333 -0.226617007 Down 0.252200158 Rab30 "RAB30, member RAS oncogene family" K07917|1|6e-112|407|pale:102884725|Ras-related protein Rab-30 GO:0005795//Golgi stack;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0035556//intracellular signal transduction;GO:0006996//organelle organization;GO:0009154//purine ribonucleotide catabolic process;GO:0045184//establishment of protein localization gi|21361418|ref|NP_055303.2|/5.16857e-111/ras-related protein Rab-30 [Homo sapiens] 18606 3257 2.576666667 2.19 -0.234575044 Down 0.252200158 Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 K01122|1|0.0|1801|mmu:18606|ectonucleotide pyrophosphatase/phosphodiesterase family member 2 [EC:3.1.4.39] - - - - 69535 919 7.296666667 6.6 -0.144771524 Down 0.252134341 Ten1 TEN1 telomerase capping complex subunit - GO:0000783//nuclear telomere cap complex GO:0003676//nucleic acid binding - "gi|148702617|gb|EDL34564.1|/1.33352e-100/mCG6823, partial [Mus musculus]" 76826 1230 7.076666667 7.773333333 0.135463417 Up 0.252134341 Nubpl nucleotide binding protein-like K03593|1|6e-165|582|mmu:76826|ATP-binding protein involved in chromosome partitioning GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0032550 GO:0010257//NADH dehydrogenase complex assembly;GO:0007005//mitochondrion organization gi|167234411|ref|NP_084036.2|/4.64597e-164/iron-sulfur protein NUBPL precursor [Mus musculus] 239555 5099 7.416666667 6.716666667 -0.143025497 Down 0.252134341 Mief1 mitochondrial elongation factor 1 K17834|1|1e-09|69.3|nve:NEMVE_v1g211400|cyclic GMP-AMP synthase [EC:2.7.7.86] GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane - - "gi|148672661|gb|EDL04608.1|/0/Smith-Magenis syndrome chromosome region, candidate 7-like (human), isoform CRA_b, partial [Mus musculus]" 235086 6787.74 0.5 0.73 0.545968369 Up 0.252115537 Igsf9b "immunoglobulin superfamily, member 9B" - - - - gi|193788661|ref|NP_001028495.2|/0/protein turtle homolog B isoform 2 precursor [Mus musculus] 100041965 963 82.12333333 77.04 -0.092184484 Down 0.252087329 Oaz1-ps "ornithine decarboxylase antizyme 1, pseudogene" K16548|1|7e-99|276|tup:102496602|ornithine decarboxylase antizyme 1 - GO:0005488//binding;GO:0004857//enzyme inhibitor activity GO:0044092//negative regulation of molecular function;GO:0006576//cellular biogenic amine metabolic process gi|1924976|gb|AAB96330.1|/1.03585e-123/ornithine decarboxylase antizyme [Mus musculus] 12509 1751.26 78.41 83.47666667 0.090335333 Up 0.252068525 Cd59a CD59a antigen K04008|1|2e-60|236|mmu:12509|CD59 antigen GO:0046658//anchored component of plasma membrane;GO:0043209//myelin sheath;GO:0009986//cell surface;GO:0044421;GO:0046658//anchored component of plasma membrane;GO:0043209//myelin sheath;GO:0009986//cell surface;GO:0044421 - GO:0001525//angiogenesis;GO:0019835//cytolysis;GO:0001818//negative regulation of cytokine production;GO:0009968//negative regulation of signal transduction;GO:0006915//apoptotic process;GO:0001905;GO:0002698;GO:0002673//regulation of acute inflammatory response;GO:0042098//T cell proliferation;GO:0001525//angiogenesis;GO:0019835//cytolysis;GO:0001818//negative regulation of cytokine production;GO:0009968//negative regulation of signal transduction;GO:0006915//apoptotic process;GO:0001905;GO:0002698;GO:0002673//regulation of acute inflammatory response;GO:0042098//T cell proliferation gi|6671714|ref|NP_031678.1|/1.72813e-59/CD59A glycoprotein precursor [Mus musculus] 225283 4297 10.97333333 11.94 0.121801002 Up 0.252059122 Rprd1a regulation of nuclear pre-mRNA domain containing 1A "K15559|1|2e-142|509|acs:100553849|regulator of Ty1 transposition protein 103;K14695|3|4e-118|429|dre:560642|solute carrier family 30 (zinc transporter), member 8" GO:0044451 "GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006796//phosphate-containing compound metabolic process gi|60360126|dbj|BAD90282.1|/2.39082e-178/mKIAA4077 protein [Mus musculus] 240038 4880 0.573333333 0.813333333 0.504472583 Up 0.251974501 Gm4944 zinc finger protein 994 K09228|1|0.0|1438|mmu:240038|KRAB domain-containing zinc finger protein - - - gi|326633225|ref|NP_001192024.1|/0/uncharacterized protein LOC240038 [Mus musculus] 18036 1389.35 25.01666667 26.84666667 0.1018534 Up 0.251936891 Nfkbib "nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta" K02581|1|2e-168|595|mmu:18036|NF-kappa-B inhibitor beta GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0008134//transcription factor binding;GO:0008134//transcription factor binding GO:0042994//cytoplasmic sequestering of transcription factor;GO:0007154//cell communication;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0007154//cell communication gi|24111253|ref|NP_035038.2|/1.38982e-167/NF-kappa-B inhibitor beta [Mus musculus] 232086 1510 28.55666667 26.72666667 -0.095547671 Down 0.251936891 Tmem150a transmembrane protein 150A - GO:0031224//intrinsic component of membrane - GO:0008152//metabolic process "gi|148666554|gb|EDK98970.1|/4.45909e-154/transmembrane protein 150, isoform CRA_c, partial [Mus musculus]" 20510 3708 1.07 1.36 0.345995855 Up 0.251918086 Slc1a1 "solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1" "K05612|1|0.0|911|mmu:20510|solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter), member 1" GO:0031224//intrinsic component of membrane GO:0005283//sodium:amino acid symporter activity;GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0016597//amino acid binding GO:0006814//sodium ion transport;GO:0051259//protein oligomerization;GO:0043090//amino acid import;GO:0015813//L-glutamate transport gi|6678001|ref|NP_033225.1|/0/excitatory amino acid transporter 3 [Mus musculus] 104799 2551.36 15.88333333 17.12666667 0.108730676 Up 0.251889879 Vipas39 "VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog" K10738|1|4e-40|169|hmg:100204413|DNA helicase MCM9 [EC:3.6.4.12];K01886|2|9e-20|101|tsp:Tsp_08341|glutaminyl-tRNA synthetase [EC:6.1.1.18] GO:0005768//endosome;GO:0031982//vesicle;GO:0005768//endosome;GO:0031982//vesicle;GO:0005768//endosome;GO:0031982//vesicle - "GO:0048869//cellular developmental process;GO:0007041//lysosomal transport;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0015031//protein transport;GO:0048869//cellular developmental process;GO:0007041//lysosomal transport;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0015031//protein transport;GO:0048869//cellular developmental process;GO:0007041//lysosomal transport;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0015031//protein transport" "gi|148670990|gb|EDL02937.1|/0/expressed sequence AI413782, isoform CRA_f, partial [Mus musculus]" 252967 910 0.23 0.42 0.868755467 Up 0.251739441 Ropn1l ropporin 1-like - GO:0005929//cilium GO:0019887//protein kinase regulator activity GO:0048870//cell motility;GO:0007154//cell communication gi|81868172|sp|Q9EQ00.1|ROP1L_MOUSE/5.51797e-124/RecName: Full=Ropporin-1-like protein; AltName: Full=AKAP-associated sperm protein 67122 2590 9.266666667 8.47 -0.129688508 Down 0.25165482 Nrarp Notch-regulated ankyrin repeat protein K17566|1|3e-13|80.1|acs:100565362|protein phosphatase 1 regulatory subunit 27 - - - - 22230 1988.86 26.20333333 28.01666667 0.09653497 Up 0.251626613 Ufd1l ubiquitin fusion degradation 1 like K14016|1|8e-173|609|mmu:22230|ubiquitin fusion degradation protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0019783//ubiquitin-like protein-specific protease activity;GO:0005515//protein binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0005515//protein binding GO:0048731//system development;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0048731//system development;GO:0006511//ubiquitin-dependent protein catabolic process gi|257153392|ref|NP_035802.3|/7.61376e-161/ubiquitin fusion degradation protein 1 homolog [Mus musculus] 20516 3658 73.41333333 78.26 0.092233001 Up 0.251626613 Slc20a2 "solute carrier family 20, member 2" K14640|1|0.0|1172|mmu:20516|solute carrier family 20 (sodium-dependent phosphate transporter) GO:0016021//integral component of membrane GO:0015081//sodium ion transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0015698//inorganic anion transport;GO:0044763;GO:0030001//metal ion transport gi|165377214|ref|NP_035524.2|/0/sodium-dependent phosphate transporter 2 precursor [Mus musculus] 209692 3535 1.036666667 0.773333333 -0.422789775 Down 0.251579601 Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 K15791|1|0.0|1748|mmu:209692|probable 2-oxoglutarate dehydrogenase E1 component DHKTD1 [EC:1.2.4.2] GO:0043231//intracellular membrane-bounded organelle "GO:0016624//oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;GO:0019842//vitamin binding" GO:0009060//aerobic respiration;GO:0006007//glucose catabolic process "gi|124487485|ref|NP_001074600.1|/0/probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial [Mus musculus]" 268752 2011 0.32 0.153333333 -1.061400545 Down 0.251551393 Wdfy2 WD repeat and FYVE domain containing 2 K12182|1|6e-13|78.6|obi:106883725|hepatocyte growth factor-regulated tyrosine kinase substrate - - - - 105005 3402 0.156666667 0.326666667 1.060120992 Up 0.251551393 Fam84a "family with sequence similarity 84, member A" - - - - "gi|148666046|gb|EDK98462.1|/8.04007e-166/expressed sequence AW125753, isoform CRA_b, partial [Mus musculus]" 16002 3763.63 10.82 11.78 0.12263904 Up 0.251523186 Igf2 insulin-like growth factor 2 K13769|1|2e-78|295|mmu:16002|insulin-like growth factor 2 - - - - 399566 2075 10.87333333 11.83 0.121655792 Up 0.251523186 Btbd6 BTB (POZ) domain containing 6 K10478|1|0.0|925|rno:690367|BTB/POZ domain-containing protein 3/6 GO:0044424;GO:0044424 - - gi|225543368|ref|NP_964008.2|/0/BTB/POZ domain-containing protein 6 isoform 1 [Mus musculus] 75016 3326 1.226666667 0.95 -0.368743847 Down 0.251400955 4930480K23Rik RIKEN cDNA 4930480K23 gene - - - - - 320162 2676.57 2.396666667 2.793333333 0.220958473 Up 0.251353943 Cep95 centrosomal protein 95 K16544|1|0.0|1588|mmu:320162|centrosomal protein CEP95 GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005815//microtubule organizing center;GO:0005819//spindle - - gi|262331533|ref|NP_001160157.1|/0/centrosomal protein of 95 kDa isoform 2 [Mus musculus] 665976 1689 0.653333333 0.433333333 -0.592342031 Down 0.251335139 Vmn2r-ps129 "vomeronasal 2, receptor, pseudogene 129" K04613|1|4e-14|82.4|rno:502285|vomeronasal 2 receptor;K04612|2|3e-12|76.3|cge:100772918|calcium-sensing receptor GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|672034880|ref|XP_008757097.1|/1.4225e-18/PREDICTED: vomeronasal type-2 receptor 116 isoform X2 [Rattus norvegicus] 16765 1070 15.00333333 16.22333333 0.11278721 Up 0.251269322 Stmn1 stathmin 1 K04381|1|2e-80|301|mcc:719733|stathmin GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0008092//cytoskeletal protein binding;GO:0060089 GO:0000278//mitotic cell cycle;GO:0007417//central nervous system development;GO:0051707//response to other organism;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0031111//negative regulation of microtubule polymerization or depolymerization;GO:0006928//movement of cell or subcellular component;GO:0007165//signal transduction "gi|537229315|gb|ERE83778.1|/2.0817e-94/platelet-activating factor acetylhydrolase 2, cytoplasmic-like protein [Cricetulus griseus]" 26922 1337 15 16.22 0.112811319 Up 0.251269322 Mecr mitochondrial trans-2-enoyl-CoA reductase K07512|1|0.0|736|mmu:26922|mitochondrial trans-2-enoyl-CoA reductase [EC:1.3.1.38] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0005102//receptor binding" GO:0006631//fatty acid metabolic process "gi|227116358|ref|NP_079573.2|/0/trans-2-enoyl-CoA reductase, mitochondrial precursor [Mus musculus]" 231670 3909 15.55666667 16.77333333 0.108636455 Up 0.251269322 Fbxo21 F-box protein 21 K10301|1|0.0|1238|mmu:231670|F-box protein 21 - GO:0003676//nucleic acid binding - "gi|148687854|gb|EDL19801.1|/0/F-box only protein 21, isoform CRA_a, partial [Mus musculus]" 18441 3755.71 6.13 5.51 -0.153834755 Down 0.251250517 P2ry1 "purinergic receptor P2Y, G-protein coupled 1" "K04270|1|0.0|696|mmu:18441|purinergic receptor P2Y, G protein-coupled, 1" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane GO:0031685//adenosine receptor binding;GO:0001608;GO:0032550;GO:0001609//G-protein coupled adenosine receptor activity;GO:0046983//protein dimerization activity;GO:0031685//adenosine receptor binding;GO:0001608;GO:0032550;GO:0001609//G-protein coupled adenosine receptor activity;GO:0046983//protein dimerization activity GO:0007631//feeding behavior;GO:0035588;GO:0007009//plasma membrane organization;GO:0006811//ion transport;GO:0042311//vasodilation;GO:0043084//penile erection;GO:0043410//positive regulation of MAPK cascade;GO:0016477//cell migration;GO:0007600//sensory perception;GO:0010033//response to organic substance;GO:0009605//response to external stimulus;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0032959//inositol trisphosphate biosynthetic process;GO:0046879//hormone secretion;GO:0044092//negative regulation of molecular function;GO:0007417//central nervous system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0044767//single-organism developmental process;GO:0009611//response to wounding;GO:0014061//regulation of norepinephrine secretion;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007631//feeding behavior;GO:0035588;GO:0007009//plasma membrane organization;GO:0006811//ion transport;GO:0042311//vasodilation;GO:0043084//penile erection;GO:0043410//positive regulation of MAPK cascade;GO:0016477//cell migration;GO:0007600//sensory perception;GO:0010033//response to organic substance;GO:0009605//response to external stimulus;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0032959//inositol trisphosphate biosynthetic process;GO:0046879//hormone secretion;GO:0044092//negative regulation of molecular function;GO:0007417//central nervous system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0044767//single-organism developmental process;GO:0009611//response to wounding;GO:0014061//regulation of norepinephrine secretion;GO:0051480//regulation of cytosolic calcium ion concentration gi|6679193|ref|NP_032798.1|/0/P2Y purinoceptor 1 [Mus musculus] 104662 3395 6.396666667 5.78 -0.146250813 Down 0.251250517 Tsr1 TSR1 20S rRNA accumulation K14799|1|0.0|1429|mmu:104662|pre-rRNA-processing protein TSR1 GO:0043231//intracellular membrane-bounded organelle - GO:0022613//ribonucleoprotein complex biogenesis gi|126506294|ref|NP_796299.2|/0/pre-rRNA-processing protein TSR1 homolog [Mus musculus] 56488 969 4.903333333 5.476666667 0.159535234 Up 0.251156493 Nxt1 NTF2-related export protein 1 K14285|1|5e-77|290|ptg:102962503|NTF2-related export protein 1/2 - - - - 73728 3950 0.836666667 0.596666667 -0.487727777 Down 0.251090677 Psd pleckstrin and Sec7 domain containing K12494|1|0.0|1716|mmu:73728|PH and SEC7 domain-containing protein - - - "gi|148710042|gb|EDL41988.1|/0/pleckstrin and Sec7 domain containing, isoform CRA_b, partial [Mus musculus]" 321014 1409 0.886666667 1.16 0.38766106 Up 0.251062469 4930473A02Rik RIKEN cDNA 4930473A02 gene K18032|1|1e-31|91.3|shr:100916761|receptor-type tyrosine-protein phosphatase A [EC:3.1.3.48] - - - - 208820 1498 0.863333333 1.13 0.388333175 Up 0.251062469 Triqk triple QxxK/R motif containing - GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane - - gi|26339432|dbj|BAC33387.1|/4.72656e-39/unnamed protein product [Mus musculus] 66676 3452 17.01333333 15.80333333 -0.106436936 Down 0.250930836 Tmed7 transmembrane emp24 protein transport domain containing 7 K20349|1|5e-106|388|mmu:66676|p24 family protein gamma-3 GO:0030134//ER to Golgi transport vesicle;GO:0030137//COPI-coated vesicle;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane - GO:0045184//establishment of protein localization gi|255003819|ref|NP_079974.1|/4.70288e-105/transmembrane emp24 domain-containing protein 7 precursor [Mus musculus] 268749 3443 16.02333333 17.23333333 0.105027477 Up 0.250930836 Rnf31 ring finger protein 31 K11974|1|0.0|2070|mmu:268749|E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.27] GO:0044444//cytoplasmic part;GO:0000151//ubiquitin ligase complex;GO:0005887//integral component of plasma membrane GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0032182//ubiquitin-like protein binding GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0000209//protein polyubiquitination;GO:0050851//antigen receptor-mediated signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|40254409|ref|NP_919327.2|/0/E3 ubiquitin-protein ligase RNF31 [Mus musculus] 56631 1710 0.116666667 0.276666667 1.245756414 Up 0.250893227 Trim17 tripartite motif-containing 17 K12007|1|0.0|913|mmu:56631|tripartite motif-containing protein 17 [EC:2.3.2.27] GO:0044464 GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0016567//protein ubiquitination gi|33859757|ref|NP_112449.1|/0/E3 ubiquitin-protein ligase TRIM17 [Mus musculus] 641340 1789 9.003333333 8.216666667 -0.131905993 Down 0.250893227 Nrbf2 nuclear receptor binding factor 2 K18758|1|5e-12|75.5|ggo:101132271|DIS3-like exonuclease 2 [EC:3.1.13.-] - - - - 66866 3934 3.59 4.08 0.184585308 Up 0.250846215 Nhlrc2 NHL repeat containing 2 K12035|1|3e-07|60.8|aqu:105312083|tripartite motif-containing protein 71 [EC:2.3.2.27] - - - gi|29789158|ref|NP_080087.1|/0/NHL repeat-containing protein 2 [Mus musculus] 70028 7331 3.786666667 3.323333333 -0.188297425 Down 0.250808605 Dopey2 dopey family member 2 K19476|1|2e-45|188|tsp:Tsp_05230|vacuolar protein sorting-associated protein IST1 - - GO:0045184//establishment of protein localization gi|62243808|ref|NP_081569.1|/0/protein dopey-2 isoform 1 [Mus musculus] 192652 6976 3.776666667 3.313333333 -0.188830104 Down 0.250808605 Wdr81 WD repeat domain 81 K17601|1|0.0|3596|mmu:192652|WD repeat-containing protein 81 - GO:0016740//transferase activity GO:0010921//regulation of phosphatase activity gi|242118003|ref|NP_620400.2|/0/WD repeat-containing protein 81 [Mus musculus] 54124 757 3.276666667 3.733333333 0.188235411 Up 0.250808605 Cks1b CDC28 protein kinase 1b K02219|1|6e-42|149|cge:103160037|cyclin-dependent kinase regulatory subunit CKS1 GO:0031981//nuclear lumen "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005488//binding;GO:0019887//protein kinase regulator activity" GO:0051726//regulation of cell cycle;GO:0044772//mitotic cell cycle phase transition;GO:0051320;GO:0006796//phosphate-containing compound metabolic process;GO:0051318 gi|148681025|gb|EDL12972.1|/1.21517e-48/mCG117418 [Mus musculus] 225288 6251 66.29666667 70.71666667 0.093113938 Up 0.250799203 Fhod3 formin homology 2 domain containing 3 K02184|1|2e-26|125|phu:Phum_PHUM602670|formin 2;K05741|2|3e-25|112|crg:105331485|diaphanous 2 GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0030239//myofibril assembly;GO:0030041//actin filament polymerization;GO:0030239//myofibril assembly;GO:0030041//actin filament polymerization;GO:0030239//myofibril assembly;GO:0030041//actin filament polymerization gi|576067827|ref|NP_001276583.1|/0/FH1/FH2 domain-containing protein 3 isoform 2 [Mus musculus] 17691 4512 23.6 25.36333333 0.103957502 Up 0.2507898 Sik1 salt inducible kinase 1 K19008|1|0.0|1495|mmu:17691|serine/threonine-protein kinase SIK1 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0003713//transcription coactivator activity;GO:0019900//kinase binding GO:0000278//mitotic cell cycle;GO:0006094//gluconeogenesis;GO:0014902//myotube differentiation;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0006468//protein phosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0035051//cardiocyte differentiation;GO:0010866//regulation of triglyceride biosynthetic process;GO:0006814//sodium ion transport;GO:0035556//intracellular signal transduction gi|110815830|ref|NP_034961.2|/0/serine/threonine-protein kinase SIK1 [Mus musculus] 75705 3871 70.83 66.41666667 -0.092815224 Down 0.2507898 Eif4b eukaryotic translation initiation factor 4B K03258|1|0.0|715|mmu:75705|translation initiation factor 4B - GO:0003676//nucleic acid binding - gi|74213040|dbj|BAE41664.1|/0/unnamed protein product [Mus musculus] 17350 2593 4.216666667 4.733333333 0.166753545 Up 0.250723984 Mlh1 mutL homolog 1 K08734|1|0.0|1419|mmu:17350|DNA mismatch repair protein MLH1 GO:0043073//germ cell nucleus;GO:0032300//mismatch repair complex;GO:0000794//condensed nuclear chromosome GO:0032550;GO:0030983//mismatched DNA binding "GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0007140//male meiosis;GO:0000019//regulation of mitotic recombination;GO:0007292//female gamete generation;GO:0048232//male gamete generation;GO:0014070//response to organic cyclic compound;GO:0000726;GO:0045143//homologous chromosome segregation;GO:0002204//somatic recombination of immunoglobulin genes involved in immune response;GO:0007131//reciprocal meiotic recombination" gi|255958238|ref|NP_081086.2|/0/DNA mismatch repair protein Mlh1 [Mus musculus] 76108 4174 4.62 4.103333333 -0.171096496 Down 0.250723984 Rap2a RAS related protein 2a K07837|1|8e-91|338|pon:100172918|Ras-related protein Rap-2A GO:0010008//endosome membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0001934//positive regulation of protein phosphorylation;GO:0007265//Ras protein signal transduction;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0030036//actin cytoskeleton organization;GO:0007254//JNK cascade;GO:0008104//protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0016477//cell migration gi|686744183|ref|XP_009247013.1|/6.90126e-90/PREDICTED: ras-related protein Rap-2a [Pongo abelii] 211401 4946.99 4.523333333 4.006666667 -0.174983825 Down 0.250723984 Mtss1 metastasis suppressor 1 K20128|1|0.0|1324|rno:362918|metastasis suppressor protein 1 GO:0005856//cytoskeleton;GO:0005856//cytoskeleton "GO:0030674//protein binding, bridging;GO:0003779//actin binding;GO:0019904//protein domain specific binding;GO:0030674//protein binding, bridging;GO:0003779//actin binding;GO:0019904//protein domain specific binding" GO:0033554//cellular response to stress;GO:0008154//actin polymerization or depolymerization;GO:0060562//epithelial tube morphogenesis;GO:0008285//negative regulation of cell proliferation;GO:0035850;GO:0007154//cell communication;GO:0050673//epithelial cell proliferation;GO:0030031//cell projection assembly;GO:0033554//cellular response to stress;GO:0008154//actin polymerization or depolymerization;GO:0060562//epithelial tube morphogenesis;GO:0008285//negative regulation of cell proliferation;GO:0035850;GO:0007154//cell communication;GO:0050673//epithelial cell proliferation;GO:0030031//cell projection assembly gi|37359942|dbj|BAC97949.1|/0/mKIAA0429 protein [Mus musculus] 243914 3444 1.32 1.633333333 0.307281319 Up 0.250648765 Lgi4 "leucine-rich repeat LGI family, member 4" K19999|1|7e-143|511|lcm:102367021|leucine-rich repeat LGI family member 3 GO:0044421 - GO:0008283//cell proliferation;GO:0014044//Schwann cell development;GO:0008366//axon ensheathment;GO:0048469//cell maturation;GO:0007626//locomotory behavior gi|74145129|dbj|BAE22223.1|/0/unnamed protein product [Mus musculus] 12615 1464.75 15.91 14.71333333 -0.112809707 Down 0.25059235 Cenpa centromere protein A K11495|1|3e-29|132|mmu:12615|histone H3-like centromeric protein A - - - - 170639 3496 0.49 0.29 -0.756728849 Down 0.25059235 Olfr78 olfactory receptor 78 K04257|1|0.0|636|mmu:170639|olfactory receptor GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0007166//cell surface receptor signaling pathway;GO:0007608//sensory perception of smell gi|18700008|ref|NP_570936.1|/1.00644e-179/olfactory receptor 51E2 [Mus musculus] 15214 2549 2.366666667 2 -0.242856524 Down 0.250582948 Hey2 hairy/enhancer-of-split related with YRPW motif 2 K09091|1|3e-123|445|mmu:15214|hairy and enhancer of split related with YRPW motif GO:0070822//Sin3-type complex "GO:0003696//satellite DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0019899//enzyme binding" GO:0002027//regulation of heart rate;GO:0003177;GO:0008284//positive regulation of cell proliferation;GO:0043392//negative regulation of DNA binding;GO:0003299;GO:0003188//heart valve formation;GO:0042491//auditory receptor cell differentiation;GO:0001837//epithelial to mesenchymal transition;GO:0055001//muscle cell development;GO:0009798//axis specification;GO:0007219//Notch signaling pathway;GO:0035907//dorsal aorta development;GO:0034622//cellular macromolecular complex assembly;GO:0003281//ventricular septum development;GO:0048844//artery morphogenesis;GO:0045595//regulation of cell differentiation;GO:0003209//cardiac atrium morphogenesis;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0051145//smooth muscle cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001570//vasculogenesis;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0055006//cardiac cell development;GO:0010659//cardiac muscle cell apoptotic process;GO:0014897;GO:0003186//tricuspid valve morphogenesis;GO:0060837//blood vessel endothelial cell differentiation;GO:0048568//embryonic organ development gi|7305159|ref|NP_038932.1|/2.29073e-122/hairy/enhancer-of-split related with YRPW motif protein 2 [Mus musculus] 58996 5450 11.40333333 10.46 -0.124572752 Down 0.250582948 Arhgap23 Rho GTPase activating protein 23 K20315|1|0.0|2218|rno:303501|Rho GTPase-activating protein 21/23 - - - gi|134035015|sp|Q69ZH9.2|RHG23_MOUSE/0/RecName: Full=Rho GTPase-activating protein 23; AltName: Full=Rho-type GTPase-activating protein 23 71721 3294 1.906666667 1.573333333 -0.277228287 Down 0.250507729 Fam13c "family with sequence similarity 13, member C" - - - - gi|219555651|ref|NP_077206.3|/0/protein FAM13C isoform 1 [Mus musculus] 54122 4607 1.873333333 1.546666667 -0.276445325 Down 0.250507729 Uevld UEV and lactate/malate dehyrogenase domains K00016|1|1e-59|235|phd:102327748|L-lactate dehydrogenase [EC:1.1.1.27] - "GO:0036094//small molecule binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors" GO:0005975//carbohydrate metabolic process;GO:0036211//protein modification process;GO:0045184//establishment of protein localization;GO:0044710 gi|104294890|ref|NP_001035785.1|/0/ubiquitin-conjugating enzyme E2 variant 3 [Mus musculus] 226418 3843 0.28 0.12 -1.222392421 Down 0.250507729 Yod1 YOD1 deubiquitinase K13719|1|0.0|701|mmu:226418|ubiquitin thioesterase OTU1 [EC:3.1.2.-] GO:0044464 GO:0046914//transition metal ion binding;GO:0019783//ubiquitin-like protein-specific protease activity GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0019752//carboxylic acid metabolic process;GO:0016579//protein deubiquitination;GO:0035966//response to topologically incorrect protein;GO:0006984//ER-nucleus signaling pathway gi|148707790|gb|EDL39737.1|/0/mCG2637 [Mus musculus] 17972 1463 1.56 1.893333333 0.2793824 Up 0.250507729 Ncf4 neutrophil cytosolic factor 4 K08012|1|0.0|676|mmu:17972|neutrophil cytosolic factor 4 GO:0044444//cytoplasmic part;GO:0005887//integral component of plasma membrane GO:0005543//phospholipid binding GO:0044763 gi|254540078|ref|NP_032703.2|/0/neutrophil cytosol factor 4 [Mus musculus] 68797 1545 1.576666667 1.91 0.276694955 Up 0.250507729 Pdgfrl platelet-derived growth factor receptor-like K05098|1|8e-24|114|dre:554230|kinase insert domain protein receptor [EC:2.7.10.1];K05096|4|2e-20|102|sko:100313537|FMS-like tyrosine kinase 1 [EC:2.7.10.1] - - - gi|170763511|ref|NP_081116.3|/0/platelet-derived growth factor receptor-like protein precursor [Mus musculus] 12428 2827 1.54 1.87 0.280107919 Up 0.250507729 Ccna2 cyclin A2 K06627|1|0.0|845|mmu:12428|cyclin A GO:0045120//pronucleus GO:0019900//kinase binding "GO:0006351//transcription, DNA-templated;GO:0043627//response to estrogen;GO:0043434//response to peptide hormone;GO:0008284//positive regulation of cell proliferation;GO:0007264//small GTPase mediated signal transduction;GO:0051726//regulation of cell cycle;GO:0009887//organ morphogenesis;GO:0000087//mitotic M phase" gi|161353444|ref|NP_033958.2|/0/cyclin-A2 [Mus musculus] 18458 2842 68.20666667 63.94333333 -0.093118805 Down 0.250404303 Pabpc1 "poly(A) binding protein, cytoplasmic 1" K13126|1|0.0|1193|chx:102175779|polyadenylate-binding protein GO:0035770//ribonucleoprotein granule;GO:0005681//spliceosomal complex;GO:0044444//cytoplasmic part "GO:0090079//translation regulator activity, nucleic acid binding;GO:0005515//protein binding;GO:0036094//small molecule binding;GO:0003729//mRNA binding" "GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006412//translation;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0043488//regulation of mRNA stability;GO:0031124//mRNA 3'-end processing;GO:0000377" gi|926708692|ref|XP_005689254.2|/0/PREDICTED: polyadenylate-binding protein 1 isoform X1 [Capra hircus] 50708 725 69.75333333 73.99666667 0.085198122 Up 0.250385498 Hist1h1c "histone cluster 1, H1c" K11275|1|5e-32|139|mmu:50708|histone H1/5 - - - - 320365 10753 16.77666667 15.58666667 -0.106143668 Down 0.250376095 Fry FRY microtubule binding protein - - - - - 66394 2098.65 22.83333333 24.55 0.104581537 Up 0.250329083 Nosip nitric oxide synthase interacting protein K13125|1|7e-172|606|mmu:66394|nitric oxide synthase-interacting protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0032769//negative regulation of monooxygenase activity;GO:0032769//negative regulation of monooxygenase activity gi|13384956|ref|NP_079809.1|/6.25752e-171/nitric oxide synthase-interacting protein isoform 1 [Mus musculus] 56390 719 23.22333333 24.94333333 0.103079212 Up 0.250329083 Sssca1 Sjogren's syndrome/scleroderma autoantigen 1 homolog (human) K11984|1|8e-07|56.2|tsp:Tsp_03550|U4/U6.U5 tri-snRNP-associated protein 1 - GO:0005515//protein binding - "gi|148701223|gb|EDL33170.1|/2.93332e-90/mCG19861, isoform CRA_b, partial [Mus musculus]" 20191 16813 67.10333333 62.92 -0.092865763 Down 0.250263267 Ryr2 "ryanodine receptor 2, cardiac" K04962|1|0.0|9380|mmu:20191|ryanodine receptor 2 GO:0034703//cation channel complex;GO:0042995//cell projection;GO:0005886//plasma membrane;GO:0031674//I band;GO:0033017//sarcoplasmic reticulum membrane GO:0051018//protein kinase A binding;GO:0046872//metal ion binding;GO:0097159//organic cyclic compound binding GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0002027//regulation of heart rate;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0016055//Wnt signaling pathway;GO:0003214//cardiac left ventricle morphogenesis;GO:0032781//positive regulation of ATPase activity;GO:0010644//cell communication by electrical coupling;GO:0031667//response to nutrient levels;GO:0006970//response to osmotic stress;GO:0031000//response to caffeine;GO:0010038//response to metal ion;GO:0086019//cell-cell signaling involved in cardiac conduction;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0070972//protein localization to endoplasmic reticulum;GO:0019722//calcium-mediated signaling;GO:0009593//detection of chemical stimulus;GO:0014897 gi|124430578|ref|NP_076357.2|/0/ryanodine receptor 2 [Mus musculus] 270058 3284 6.66 7.34 0.140257886 Up 0.250253864 Map1s microtubule-associated protein 1S K10429|1|0.0|1412|mmu:270058|microtubule-associated protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding;GO:0003779//actin binding;GO:0004518//nuclease activity;GO:0015631//tubulin binding GO:0012501//programmed cell death;GO:0031175//neuron projection development;GO:0000226//microtubule cytoskeleton organization "gi|148696944|gb|EDL28891.1|/0/microtubule-associated protein 1S, isoform CRA_a, partial [Mus musculus]" 68964 4181.97 6.296666667 5.683333333 -0.147850962 Down 0.250225657 Ctc1 CTS telomere maintenance complex component 1 - GO:0000783//nuclear telomere cap complex;GO:0000783//nuclear telomere cap complex;GO:0000783//nuclear telomere cap complex;GO:0000783//nuclear telomere cap complex GO:0043566//structure-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0043566//structure-specific DNA binding GO:0040007//growth;GO:0007569//cell aging;GO:0048534//hematopoietic or lymphoid organ development;GO:0008284//positive regulation of cell proliferation;GO:0000723//telomere maintenance;GO:0033554//cellular response to stress;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006260//DNA replication;GO:0040007//growth;GO:0007569//cell aging;GO:0048534//hematopoietic or lymphoid organ development;GO:0008284//positive regulation of cell proliferation;GO:0000723//telomere maintenance;GO:0033554//cellular response to stress;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006260//DNA replication;GO:0040007//growth;GO:0007569//cell aging;GO:0048534//hematopoietic or lymphoid organ development;GO:0008284//positive regulation of cell proliferation;GO:0000723//telomere maintenance;GO:0033554//cellular response to stress;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006260//DNA replication;GO:0040007//growth;GO:0007569//cell aging;GO:0048534//hematopoietic or lymphoid organ development;GO:0008284//positive regulation of cell proliferation;GO:0000723//telomere maintenance;GO:0033554//cellular response to stress;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006260//DNA replication gi|219689064|ref|NP_001013274.2|/0/CST complex subunit CTC1 isoform a [Mus musculus] 59024 8464 6.333333333 5.723333333 -0.146109379 Down 0.250225657 Med12 mediator complex subunit 12 K15162|1|0.0|3638|mmu:59024|mediator of RNA polymerase II transcription subunit 12 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding GO:0003401//axis elongation;GO:0014020;GO:0006366//transcription from RNA polymerase II promoter;GO:0035567//non-canonical Wnt signaling pathway;GO:0030518//intracellular steroid hormone receptor signaling pathway gi|125628662|ref|NP_067496.2|/0/mediator of RNA polymerase II transcription subunit 12 [Mus musculus] 17240 1379 0.363333333 0.573333333 0.65808043 Up 0.250178645 Mdfi MyoD family inhibitor - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0006366//transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0048562//embryonic organ morphogenesis;GO:0051100//negative regulation of binding;GO:0009798//axis specification;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0000187//activation of MAPK activity;GO:0006366//transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0048562//embryonic organ morphogenesis;GO:0051100//negative regulation of binding;GO:0009798//axis specification;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0000187//activation of MAPK activity;GO:0006366//transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0048562//embryonic organ morphogenesis;GO:0051100//negative regulation of binding;GO:0009798//axis specification;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0000187//activation of MAPK activity;GO:0006366//transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0048562//embryonic organ morphogenesis;GO:0051100//negative regulation of binding;GO:0009798//axis specification;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0000187//activation of MAPK activity gi|158303328|ref|NP_034913.2|/3.8416e-109/myoD family inhibitor isoform 1 [Mus musculus] 20290 505 0.01 0.11 3.459431619 Up 0.250141036 Ccl1 chemokine (C-C motif) ligand 1 "K05514|1|5e-42|171|mmu:20290|C-C motif chemokine, other" GO:0044421 GO:0005125//cytokine activity GO:0002376//immune system process;GO:0042221//response to chemical gi|6755424|ref|NP_035459.1|/3.57963e-41/C-C motif chemokine 1 precursor [Mus musculus] 67339 529 0.11 0.01 -3.459431619 Down 0.250141036 1700066J03Rik RIKEN cDNA 1700066J03 gene - - - - - 80782 2212 0.01 0.11 3.459431619 Up 0.250141036 Klrb1b killer cell lectin-like receptor subfamily B member 1B K06543|1|2e-114|416|mmu:80782|killer cell lectin-like receptor subfamily B GO:0016021//integral component of membrane;GO:0009986//cell surface GO:0042802//identical protein binding GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0046649//lymphocyte activation;GO:0001911 gi|222136602|ref|NP_085102.4|/1.63911e-113/killer cell lectin-like receptor subfamily B member 1B allele B [Mus musculus] 75053 495 0.11 0.01 -3.459431619 Down 0.250141036 Kif16bos "kinesin family member 16B, opposite strand" - - - - - 545279 1713 0.01 0.11 3.459431619 Up 0.250141036 Ms4a15 "membrane-spanning 4-domains, subfamily A, member 15" "K19928|1|3e-28|129|clv:102089886|zona pellucida sperm-binding protein 3;K06466|4|3e-16|89.4|shr:100929008|membrane-spanning 4-domains, subfamily A, member 1" GO:0031224//intrinsic component of membrane - - gi|85702258|ref|NP_001030070.1|/2.45339e-135/membrane-spanning 4-domains subfamily A member 15 [Mus musculus] 18503 2639 0.11 0.01 -3.459431619 Down 0.250141036 Pax1 paired box 1 K09382|1|0.0|763|mmu:18503|paired box protein 1/9 - - - gi|568915775|ref|XP_006498974.1|/0/PREDICTED: paired box protein Pax-1 isoform X1 [Mus musculus] 333588 414 0.01 0.113333333 3.502500341 Up 0.250141036 Gm15104 predicted gene 15104 - - - - gi|197384598|ref|NP_001094971.1|/3.05001e-68/uncharacterized protein LOC333588 [Mus musculus] 50782 2006 0.01 0.113333333 3.502500341 Up 0.250141036 Rgs11 regulator of G-protein signaling 11 K16449|1|0.0|967|mmu:50782|regulator of G-protein signaling GO:0030425//dendrite;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0032991//macromolecular complex GO:0008047//enzyme activator activity;GO:0005488//binding GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway gi|124486718|ref|NP_001074538.1|/0/regulator of G-protein signaling 11 [Mus musculus] 235712 1260 0.01 0.11 3.459431619 Up 0.250141036 Mrgpra2b "MAS-related GPR, member A2B" K08396|1|4e-99|363|mmu:668725|Mas-related G protein-coupled receptor member X GO:0016020//membrane GO:0008528//G-protein coupled peptide receptor activity GO:0007267//cell-cell signaling;GO:0007186//G-protein coupled receptor signaling pathway gi|188528700|ref|NP_694741.2|/2.56143e-149/mas-related G-protein coupled receptor member A2 [Mus musculus] 75528 805 0.01 0.113333333 3.502500341 Up 0.250141036 Tex29 testis expressed 29 - GO:0031224//intrinsic component of membrane - - gi|58037419|ref|NP_083602.1|/4.69015e-85/testis-expressed sequence 29 protein [Mus musculus] 75086 505 0.11 0.01 -3.459431619 Down 0.250141036 4930520P13Rik RIKEN cDNA 4930520P13 gene - - - - gi|148705078|gb|EDL37025.1|/2.3196e-32/mCG62818 [Mus musculus] 212108 475 0.113333333 0.01 -3.502500341 Down 0.250141036 Rln3 relaxin 3 K05255|1|1e-64|246|mmu:212108|relaxin - GO:0005102//receptor binding - gi|27502355|ref|NP_775276.1|/7.93092e-64/relaxin-3 precursor [Mus musculus] 239027 2598 0.696666667 0.943333333 0.437299111 Up 0.250122231 Arhgap22 Rho GTPase activating protein 22 K07526|1|2e-27|127|tru:101075439|SLIT-ROBO Rho GTPase activating protein - - - gi|224967116|ref|NP_722495.3|/0/rho GTPase-activating protein 22 [Mus musculus] 23808 3303 15.86 14.67666667 -0.111868427 Down 0.250084621 Ash2l "ash2 (absent, small, or homeotic)-like (Drosophila)" K14964|1|0.0|1128|mmu:23808|Set1/Ash2 histone methyltransferase complex subunit ASH2 GO:0044665//MLL1/2 complex;GO:0044665//MLL1/2 complex;GO:0044665//MLL1/2 complex GO:0043169//cation binding;GO:0000975//regulatory region DNA binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0043169//cation binding;GO:0000975//regulatory region DNA binding;GO:0043169//cation binding;GO:0000975//regulatory region DNA binding GO:0034968//histone lysine methylation;GO:0048545//response to steroid hormone;GO:0033554//cellular response to stress;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0048545//response to steroid hormone;GO:0048534//hematopoietic or lymphoid organ development;GO:0033554//cellular response to stress;GO:0034968//histone lysine methylation;GO:0034968//histone lysine methylation;GO:0048545//response to steroid hormone;GO:0033554//cellular response to stress;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter gi|74144611|dbj|BAE27293.1|/0/unnamed protein product [Mus musculus] 13522 3975 0.966666667 1.243333333 0.36312273 Up 0.250028207 Adam28 a disintegrin and metallopeptidase domain 28 K08614|1|0.0|1323|mmu:13522|disintegrin and metalloproteinase domain-containing protein 28 [EC:3.4.24.-] - - - - 75690 3457 1.27 0.986666667 -0.364193822 Down 0.250028207 Vsig10l V-set and immunoglobulin domain containing 10 like K18656|1|2e-23|114|cge:100759427|ATP-dependent RNA helicase DDX25 [EC:3.6.4.13];K06499|2|7e-16|89.4|mmu:26367|carcinoembryonic antigen-related cell adhesion molecule - - - gi|592743501|ref|NP_001277245.1|/0/V-set and immunoglobulin domain-containing protein 10-like [Mus musculus] 72727 1599 23.26666667 24.97 0.101931286 Up 0.250009402 B3gat3 "beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)" K10158|1|1e-174|615|mmu:72727|galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 [EC:2.4.1.135] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system GO:0015020//glucuronosyltransferase activity;GO:0043169//cation binding GO:0006024//glycosaminoglycan biosynthetic process;GO:0006464//cellular protein modification process;GO:0030166//proteoglycan biosynthetic process gi|13195672|ref|NP_077218.1|/9.34499e-174/galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 [Mus musculus] 17524 2525 4.626666667 5.183333333 0.163907012 Up 0.249868367 Mpp1 "membrane protein, palmitoylated" K06103|1|1e-147|526|cmk:103177253|calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1] GO:0005856//cytoskeleton;GO:0005902//microvillus GO:0003824//catalytic activity GO:0002688//regulation of leukocyte chemotaxis gi|6678924|ref|NP_032647.1|/0/55 kDa erythrocyte membrane protein [Mus musculus] 67017 3609 4.86 5.423333333 0.158223531 Up 0.249868367 Fam210b "family with sequence similarity 210, member B" K01283|1|4e-06|57.0|ame:726599|peptidyl-dipeptidase A [EC:3.4.15.1] - - - - 231147 4549 5.48 4.916666667 -0.156495345 Down 0.249868367 Sh3tc1 SH3 domain and tetratricopeptide repeats 1 K15837|1|3e-09|67.8|dmo:Dmoj_GI22011|G-protein signaling modulator 2 - - - gi|148368971|ref|NP_919325.2|/0/SH3 domain and tetratricopeptide repeat-containing protein 1 [Mus musculus] 72590 2361 22.73666667 24.43 0.103633102 Up 0.249849562 Ppme1 protein phosphatase methylesterase 1 K13617|1|0.0|675|ngi:103749826|protein phosphatase methylesterase 1 [EC:3.1.1.89] - GO:0019888//protein phosphatase regulator activity;GO:0019903//protein phosphatase binding;GO:0051723;GO:0019900//kinase binding GO:0008214 gi|74191897|dbj|BAE32896.1|/0/unnamed protein product [Mus musculus] 56347 2896 66.56 62.59333333 -0.088646426 Down 0.249746136 Eif3c "eukaryotic translation initiation factor 3, subunit C" K03252|1|0.0|1498|mmu:56347|translation initiation factor 3 subunit C GO:0043234//protein complex;GO:0044424 "GO:0008135//translation factor activity, RNA binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding" GO:0006412//translation gi|22203755|ref|NP_666312.1|/0/eukaryotic translation initiation factor 3 subunit C [Mus musculus] 244886 2407 2.536666667 2.16 -0.231902641 Down 0.249727331 Tmem266 transmembrane protein 266 - GO:0031224//intrinsic component of membrane - - gi|27370422|ref|NP_766511.1|/0/transmembrane protein 266 [Mus musculus] 74203 3661.97 15.44 16.61333333 0.105668815 Up 0.249699124 Eif4enif1 eukaryotic translation initiation factor 4E nuclear import factor 1 K18728|1|0.0|1622|mmu:74203|eukaryotic translation initiation factor 4E transporter GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0045184//establishment of protein localization;GO:0006412//translation;GO:0045184//establishment of protein localization;GO:0006412//translation;GO:0045184//establishment of protein localization;GO:0006412//translation;GO:0045184//establishment of protein localization;GO:0006412//translation gi|262118204|ref|NP_001160020.1|/0/eukaryotic translation initiation factor 4E transporter isoform b [Mus musculus] 69072 2960 8.753333333 7.98 -0.133443764 Down 0.249680319 Ebna1bp2 EBNA1 binding protein 2 K14823|1|3e-165|585|mmu:69072|rRNA-processing protein EBP2 GO:0031981//nuclear lumen - GO:0044763;GO:0042254//ribosome biogenesis "gi|148698540|gb|EDL30487.1|/4.43697e-173/EBNA1 binding protein 2, isoform CRA_a, partial [Mus musculus]" 29809 3557 9.12 8.35 -0.127257627 Down 0.249680319 Rabgap1l RAB GTPase activating protein 1-like K20284|1|2e-152|543|ngi:103727981|Rab GTPase-activating protein 1 GO:0005768//endosome GO:0017016//Ras GTPase binding GO:0030219//megakaryocyte differentiation;GO:0008104//protein localization "gi|148707391|gb|EDL39338.1|/0/RAB GTPase activating protein 1-like, isoform CRA_b, partial [Mus musculus]" 106672 653 8.256666667 9.023333333 0.128101019 Up 0.249680319 AI413582 expressed sequence AI413582 - - - - - 20357 4556 0.24 0.43 0.841302254 Up 0.249576893 Sema5b "sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B" K06841|1|0.0|2252|mmu:20357|semaphorin 5 GO:0031224//intrinsic component of membrane - GO:0048731//system development;GO:0048869//cellular developmental process "gi|148665472|gb|EDK97888.1|/0/sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B, isoform CRA_d, partial [Mus musculus]" 17826 1226.12 22.72666667 24.39333333 0.102100816 Up 0.249511076 Fam89b "family with sequence similarity 89, member B" - - - - gi|6941999|gb|AAF32283.1|/3.06837e-40/MMTV receptor variant 1 [Mus musculus] 54646 3489 1.71 2.05 0.261627585 Up 0.249482869 Ppp1r3f "protein phosphatase 1, regulatory (inhibitor) subunit 3F" K17453|1|0.0|1151|mmu:54646|protein phosphatase 1 regulatory subunit 3F GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0030247//polysaccharide binding;GO:0019902//phosphatase binding;GO:0030247//polysaccharide binding;GO:0019902//phosphatase binding GO:0051338;GO:0051338 gi|594542446|ref|NP_613071.3|/0/protein phosphatase 1 regulatory subunit 3F isoform 2 [Mus musculus] 11807 865 1.766666667 2.11 0.25621314 Up 0.249482869 Apoa2 apolipoprotein A-II K08758|1|7e-21|82.8|mmu:11807|apolipoprotein A-II GO:0034364//high-density lipoprotein particle;GO:0034385;GO:0034364//high-density lipoprotein particle;GO:0034385;GO:0034364//high-density lipoprotein particle;GO:0034385 GO:0004857//enzyme inhibitor activity;GO:0070325//lipoprotein particle receptor binding;GO:0005543//phospholipid binding;GO:0032934//sterol binding;GO:0008047//enzyme activator activity;GO:0042802//identical protein binding;GO:0071813//lipoprotein particle binding;GO:0046983//protein dimerization activity;GO:0015248//sterol transporter activity;GO:0004857//enzyme inhibitor activity;GO:0070325//lipoprotein particle receptor binding;GO:0005543//phospholipid binding;GO:0032934//sterol binding;GO:0008047//enzyme activator activity;GO:0042802//identical protein binding;GO:0071813//lipoprotein particle binding;GO:0046983//protein dimerization activity;GO:0015248//sterol transporter activity;GO:0004857//enzyme inhibitor activity;GO:0070325//lipoprotein particle receptor binding;GO:0005543//phospholipid binding;GO:0032934//sterol binding;GO:0008047//enzyme activator activity;GO:0042802//identical protein binding;GO:0071813//lipoprotein particle binding;GO:0046983//protein dimerization activity;GO:0015248//sterol transporter activity GO:0042108//positive regulation of cytokine biosynthetic process;GO:0010608//posttranscriptional regulation of gene expression;GO:0044093;GO:0032787//monocarboxylic acid metabolic process;GO:0015914//phospholipid transport;GO:0055092//sterol homeostasis;GO:0016125//sterol metabolic process;GO:0010872//regulation of cholesterol esterification;GO:0002374//cytokine secretion involved in immune response;GO:0031960//response to corticosteroid;GO:0009895;GO:0032375//negative regulation of cholesterol transport;GO:0010901;GO:0042946//glucoside transport;GO:0009896;GO:0046165;GO:0034377//plasma lipoprotein particle assembly;GO:0051346//negative regulation of hydrolase activity;GO:0018193//peptidyl-amino acid modification;GO:0055114//oxidation-reduction process;GO:0030299//intestinal cholesterol absorption;GO:0034381//plasma lipoprotein particle clearance;GO:0009746;GO:0046339//diacylglycerol metabolic process;GO:0009887//organ morphogenesis;GO:0006644//phospholipid metabolic process;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0010608//posttranscriptional regulation of gene expression;GO:0044093;GO:0032787//monocarboxylic acid metabolic process;GO:0015914//phospholipid transport;GO:0055092//sterol homeostasis;GO:0016125//sterol metabolic process;GO:0010872//regulation of cholesterol esterification;GO:0002374//cytokine secretion involved in immune response;GO:0031960//response to corticosteroid;GO:0009895;GO:0032375//negative regulation of cholesterol transport;GO:0010901;GO:0042946//glucoside transport;GO:0009896;GO:0046165;GO:0034377//plasma lipoprotein particle assembly;GO:0051346//negative regulation of hydrolase activity;GO:0018193//peptidyl-amino acid modification;GO:0055114//oxidation-reduction process;GO:0030299//intestinal cholesterol absorption;GO:0034381//plasma lipoprotein particle clearance;GO:0009746;GO:0046339//diacylglycerol metabolic process;GO:0009887//organ morphogenesis;GO:0006644//phospholipid metabolic process;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0010608//posttranscriptional regulation of gene expression;GO:0044093;GO:0032787//monocarboxylic acid metabolic process;GO:0015914//phospholipid transport;GO:0055092//sterol homeostasis;GO:0016125//sterol metabolic process;GO:0010872//regulation of cholesterol esterification;GO:0002374//cytokine secretion involved in immune response;GO:0031960//response to corticosteroid;GO:0009895;GO:0032375//negative regulation of cholesterol transport;GO:0010901;GO:0042946//glucoside transport;GO:0009896;GO:0046165;GO:0034377//plasma lipoprotein particle assembly;GO:0051346//negative regulation of hydrolase activity;GO:0018193//peptidyl-amino acid modification;GO:0055114//oxidation-reduction process;GO:0030299//intestinal cholesterol absorption;GO:0034381//plasma lipoprotein particle clearance;GO:0009746;GO:0046339//diacylglycerol metabolic process;GO:0009887//organ morphogenesis;GO:0006644//phospholipid metabolic process gi|157951676|ref|NP_038502.2|/6.20366e-49/apolipoprotein A-II preproprotein [Mus musculus] 66899 3039.27 11.47666667 10.55333333 -0.121004925 Down 0.249482869 Fip1l1 FIP1 like 1 (S. cerevisiae) K14405|1|3e-170|602|mmu:66899|pre-mRNA 3'-end-processing factor FIP1 GO:0005849//mRNA cleavage factor complex;GO:0005849//mRNA cleavage factor complex;GO:0005849//mRNA cleavage factor complex GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0031124//mRNA 3'-end processing;GO:0031124//mRNA 3'-end processing;GO:0031124//mRNA 3'-end processing gi|56605640|ref|NP_001008296.1|/3.85937e-177/pre-mRNA 3'-end-processing factor FIP1 [Rattus norvegicus] 252876 2766.12 1.706666667 2.046666667 0.262094845 Up 0.249482869 Gin1 gypsy retrotransposon integrase 1 K19944|1|1e-13|81.3|shr:100934415|TBC1 domain family member 10;K14297|2|6e-12|75.9|ola:101162063|nuclear pore complex protein Nup98-Nup96;K10498|3|2e-09|67.4|obi:106874323|zinc finger and BTB domain-containing protein 11;K14401|4|4e-08|63.2|pxy:105386838|cleavage and polyadenylation specificity factor subunit 1;K05769|5|2e-06|57.4|gja:107124056|Rho guanine nucleotide exchange factor 4 - - - gi|894216242|ref|NP_001297702.1|/0/gypsy retrotransposon integrase-like protein 1 isoform 2 [Mus musculus] 381022 19827 7.306666667 6.633333333 -0.139479368 Down 0.249417052 Kmt2d lysine (K)-specific methyltransferase 2D K09187|1|0.0|4275|mmu:381022|histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43] - - - gi|359718904|ref|NP_001028448.3|/0/histone-lysine N-methyltransferase 2D [Mus musculus] 12371 3846.29 4.196666667 4.706666667 0.165461806 Up 0.249398247 Casp9 caspase 9 K04399|1|0.0|894|mmu:12371|caspase 9 [EC:3.4.22.62] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0004175//endopeptidase activity;GO:0033218//amide binding;GO:0019904//protein domain specific binding;GO:0019900//kinase binding;GO:0004175//endopeptidase activity;GO:0033218//amide binding;GO:0019904//protein domain specific binding;GO:0019900//kinase binding GO:0006974//cellular response to DNA damage stimulus;GO:0071385//cellular response to glucocorticoid stimulus;GO:0009636//response to toxic substance;GO:0043627//response to estrogen;GO:0009411//response to UV;GO:0043065//positive regulation of apoptotic process;GO:0010038//response to metal ion;GO:0012502//induction of programmed cell death;GO:0044767//single-organism developmental process;GO:0002237//response to molecule of bacterial origin;GO:0035556//intracellular signal transduction;GO:0019538//protein metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0071385//cellular response to glucocorticoid stimulus;GO:0009636//response to toxic substance;GO:0043627//response to estrogen;GO:0009411//response to UV;GO:0043065//positive regulation of apoptotic process;GO:0010038//response to metal ion;GO:0012502//induction of programmed cell death;GO:0044767//single-organism developmental process;GO:0002237//response to molecule of bacterial origin;GO:0035556//intracellular signal transduction;GO:0019538//protein metabolic process gi|31560479|ref|NP_056548.2|/0/caspase-9 isoform 1 precursor [Mus musculus] 20932 2863 61.04333333 64.92666667 0.088977399 Up 0.24937004 Surf4 surfeit gene 4 K20369|1|1e-145|520|chx:102170434|ER-derived vesicles protein GO:0012505//endomembrane system;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0016482//cytosolic transport;GO:0006886//intracellular protein transport;GO:0006996//organelle organization gi|926705357|ref|XP_005687391.2|/1.09514e-144/PREDICTED: surfeit locus protein 4 [Capra hircus] 72649 3499 3.326666667 2.893333333 -0.201344773 Down 0.249341833 Tmem209 transmembrane protein 209 "K03847|1|2e-08|64.7|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - - 66983 3278 3.65 4.133333333 0.179409251 Up 0.249247809 Zfp830 zinc finger protein 830 K13104|1|0.0|659|mmu:66983|zinc finger protein 830 - - - - 74360 2456 3.55 4.033333333 0.184153617 Up 0.249247809 Cep57 centrosomal protein 57 K16762|1|0.0|828|mmu:74360|centrosomal protein CEP57 GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen;GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen GO:0042802//identical protein binding;GO:0019838//growth factor binding;GO:0015631//tubulin binding;GO:0042802//identical protein binding;GO:0019838//growth factor binding;GO:0015631//tubulin binding GO:0051259//protein oligomerization;GO:0006606//protein import into nucleus;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0000226//microtubule cytoskeleton organization;GO:0007281//germ cell development;GO:0051259//protein oligomerization;GO:0006606//protein import into nucleus;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0000226//microtubule cytoskeleton organization;GO:0007281//germ cell development gi|160333432|ref|NP_080941.3|/0/centrosomal protein of 57 kDa isoform 1 [Mus musculus] 83396 3619 3.963333333 3.486666667 -0.184865863 Down 0.249247809 Glis2 GLIS family zinc finger 2 K09233|1|0.0|739|mmu:83396|zinc finger protein GLIS2 GO:0016604//nuclear body;GO:0043234//protein complex "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000975//regulatory region DNA binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0044092//negative regulation of molecular function;GO:0007224//smoothened signaling pathway;GO:0032502//developmental process "gi|148664819|gb|EDK97235.1|/0/GLIS family zinc finger 2, isoform CRA_b, partial [Mus musculus]" 54132 1524 56.51 60.35333333 0.094927264 Up 0.249181993 Pdlim1 PDZ and LIM domain 1 (elfin) K19867|1|5e-42|174|crg:105335510|LIM domain-binding protein 3 GO:0043234//protein complex;GO:0043232 GO:0003712//transcription cofactor activity;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated;GO:0006950//response to stress" gi|158635992|ref|NP_058557.2|/0/PDZ and LIM domain protein 1 [Mus musculus] 232146 1768 1.343333333 1.65 0.296648686 Up 0.249153785 Eva1a eva-1 homolog A (C. elegans) - GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle - GO:0009987//cellular process gi|537135410|gb|ERE66219.1|/4.17011e-61/hypothetical protein H671_8g19595 [Cricetulus griseus] 70099 4101 1.646666667 1.34 -0.29731554 Down 0.249153785 Smc4 structural maintenance of chromosomes 4 K06675|1|0.0|2289|mmu:70099|structural maintenance of chromosome 4 GO:0043231//intracellular membrane-bounded organelle;GO:0000793//condensed chromosome GO:0032550;GO:0046983//protein dimerization activity GO:0000070//mitotic sister chromatid segregation;GO:0030261//chromosome condensation gi|29789347|ref|NP_598547.1|/0/structural maintenance of chromosomes protein 4 [Mus musculus] 268512 2692 1.34 1.65 0.300233024 Up 0.249153785 Slc26a11 "solute carrier family 26, member 11" "K14708|1|0.0|989|mmu:268512|solute carrier family 26 (sodium-independent sulfate anion transporter), member 11" GO:0005764//lysosome;GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity GO:0015698//inorganic anion transport "gi|24047243|gb|AAH38604.1|/0/Slc26a11 protein, partial [Mus musculus]" 100503393 3089 0.366666667 0.186666667 -0.974004791 Down 0.249069164 Gm14827 predicted gene 14827 - - - - - 29820 4036 0.186666667 0.363333333 0.960829403 Up 0.249069164 Tnfrsf19 "tumor necrosis factor receptor superfamily, member 19" K05155|1|0.0|829|mmu:29820|tumor necrosis factor receptor superfamily member 19 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|256221052|ref|NP_038897.4|/0/tumor necrosis factor receptor superfamily member 19 precursor [Mus musculus] 109754 2066 62.01333333 65.80666667 0.085655307 Up 0.249059762 Cyb5r3 cytochrome b5 reductase 3 K00326|1|1e-167|592|mmu:109754|cytochrome-b5 reductase [EC:1.6.2.2] GO:0031966//mitochondrial membrane;GO:0019866//organelle inner membrane "GO:0032550;GO:0016653//oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor;GO:0050660//flavin adenine dinucleotide binding" GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process gi|19745150|ref|NP_084063.1|/9.00855e-167/NADH-cytochrome b5 reductase 3 [Mus musculus] 67255 3192.4 10.41666667 11.32333333 0.120405028 Up 0.249050359 Zfp422 zinc finger protein 422 K09228|1|7e-58|228|bom:102285807|KRAB domain-containing zinc finger protein GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0009887//organ morphogenesis;GO:0006351//transcription, DNA-templated;GO:0009887//organ morphogenesis;GO:0006351//transcription, DNA-templated;GO:0009887//organ morphogenesis;GO:0006351//transcription, DNA-templated" "gi|148667150|gb|EDK99566.1|/1.45495e-148/zinc finger protein 422, isoform CRA_b, partial [Mus musculus]" 59047 2115.16 11.07333333 10.16 -0.12418917 Down 0.249050359 Pnkp polynucleotide kinase 3'- phosphatase K08073|1|0.0|952|mmu:59047|bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0032550;GO:0051733//polydeoxyribonucleotide kinase activity;GO:0032550;GO:0051733//polydeoxyribonucleotide kinase activity;GO:0032550;GO:0051733//polydeoxyribonucleotide kinase activity;GO:0032550;GO:0051733//polydeoxyribonucleotide kinase activity GO:0006259//DNA metabolic process;GO:0009117//nucleotide metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006259//DNA metabolic process;GO:0009117//nucleotide metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006259//DNA metabolic process;GO:0009117//nucleotide metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006259//DNA metabolic process;GO:0009117//nucleotide metabolic process;GO:0006974//cellular response to DNA damage stimulus gi|568948192|ref|XP_006541103.1|/0/PREDICTED: bifunctional polynucleotide phosphatase/kinase isoform X3 [Mus musculus] 328968 1381 3.6 3.146666667 -0.194172548 Down 0.249031554 Mir143hg cardiac mesoderm enhancer-associated non-coding RNA - - - - - 58239 1394 23.42333333 25.06666667 0.097823763 Up 0.248993945 Dexi dexamethasone-induced transcript - - - - gi|148664904|gb|EDK97320.1|/2.15658e-83/dexamethasone-induced transcript [Mus musculus] 23897 1167.19 21.94333333 23.58666667 0.10418885 Up 0.248993945 Hax1 HCLS1 associated X-1 K16220|1|6e-49|196|mmu:23897|HCLS1-associated protein X-1 GO:0030135//coated vesicle;GO:0031252//cell leading edge;GO:0005635//nuclear envelope;GO:0043234//protein complex;GO:0005856//cytoskeleton;GO:0005783//endoplasmic reticulum;GO:0044459;GO:0030135//coated vesicle;GO:0031252//cell leading edge;GO:0005635//nuclear envelope;GO:0043234//protein complex;GO:0005856//cytoskeleton;GO:0005783//endoplasmic reticulum;GO:0044459 GO:0019838//growth factor binding;GO:0019838//growth factor binding GO:0001934//positive regulation of protein phosphorylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0008064//regulation of actin polymerization or depolymerization;GO:0034097//response to cytokine;GO:0031532//actin cytoskeleton reorganization;GO:0001934//positive regulation of protein phosphorylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0008064//regulation of actin polymerization or depolymerization;GO:0034097//response to cytokine;GO:0031532//actin cytoskeleton reorganization gi|6754160|ref|NP_035956.1|/7.53135e-136/HCLS1-associated protein X-1 isoform 1 [Mus musculus] 353187 4640 15.25 14.1 -0.11311408 Down 0.248956335 Nr1d2 "nuclear receptor subfamily 1, group D, member 2" K08531|1|0.0|1066|mmu:353187|nuclear receptor subfamily 1 group D member 2 GO:0031981//nuclear lumen "GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding" GO:0009755//hormone-mediated signaling pathway;GO:0006366//transcription from RNA polymerase II promoter "gi|148688702|gb|EDL20649.1|/0/nuclear receptor subfamily 1, group D, member 2, isoform CRA_a, partial [Mus musculus]" 14447 1458 0.373333333 0.583333333 0.64385619 Up 0.248946933 Gapdhs "glyceraldehyde-3-phosphate dehydrogenase, spermatogenic" "K10705|1|0.0|721|mmu:14447|glyceraldehyde-3-phosphate dehydrogenase, spermatogenic [EC:1.2.1.12]" GO:0005929//cilium;GO:0044444//cytoplasmic part;GO:0005929//cilium;GO:0044444//cytoplasmic part "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding" GO:0044710;GO:0048870//cell motility;GO:0006096//glycolytic process;GO:0007281//germ cell development;GO:0044710;GO:0048870//cell motility;GO:0006096//glycolytic process;GO:0007281//germ cell development "gi|2494630|sp|Q64467.1|G3PT_MOUSE/0/RecName: Full=Glyceraldehyde-3-phosphate dehydrogenase, testis-specific; AltName: Full=Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2; Short=GAPDH-2; AltName: Full=Spermatogenic glyceraldehyde-3-phosphate dehydrogenase" 100861753 1743 7.81 8.566666667 0.133411405 Up 0.248918726 Gm21188 "predicted gene, 21188" K15731|1|2e-27|126|pon:100435596|carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0004722//protein serine/threonine phosphatase activity GO:0006464//cellular protein modification process;GO:0010721//negative regulation of cell development;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter gi|74180694|dbj|BAE25571.1|/1.41296e-162/unnamed protein product [Mus musculus] 225326 3102 8.766666667 8.006666667 -0.130826648 Down 0.248918726 Pik3c3 "phosphoinositide-3-kinase, class 3" K00914|1|0.0|1666|mmu:225326|phosphatidylinositol 3-kinase [EC:2.7.1.137] - - - gi|42475974|ref|NP_852079.2|/0/phosphatidylinositol 3-kinase catalytic subunit type 3 [Mus musculus] 380608 2358 8.22 8.976666667 0.12704143 Up 0.248918726 Tagap1 T cell activation GTPase activating protein 1 K16546|1|1e-15|88.2|pon:100439106|FGFR1 oncogene partner GO:0044464 GO:0030695//GTPase regulator activity GO:0007154//cell communication gi|148228285|ref|NP_671511.2|/0/T-cell activation GTPase-activating protein 1 [Mus musculus] 227648 8754 8.846666667 8.083333333 -0.130183623 Down 0.248918726 Sec16a "SEC16 homolog A, endoplasmic reticulum export factor" K20353|1|0.0|4259|mmu:227648|COPII coat assembly protein SEC16 - - - gi|124378050|ref|NP_694765.2|/0/protein transport protein Sec16A [Mus musculus] 16010 2069 57.60666667 61.31666667 0.09004349 Up 0.248852909 Igfbp4 insulin-like growth factor binding protein 4 K10138|1|1e-27|127|bta:282261|insulin-like growth factor-binding protein 3 GO:0044421 GO:0019838//growth factor binding GO:0009967//positive regulation of signal transduction;GO:0006952//defense response;GO:0016049//cell growth;GO:0006006//glucose metabolic process;GO:0008283//cell proliferation;GO:0000165//MAPK cascade gi|6981086|ref|NP_034647.1|/6.11023e-131/insulin-like growth factor-binding protein 4 precursor [Mus musculus] 224826 7696 24.3 22.67333333 -0.099959809 Down 0.248834104 Ubr2 ubiquitin protein ligase E3 component n-recognin 2 K10626|1|0.0|3410|mmu:224826|E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27] GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0044427;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0044427 GO:0046914//transition metal ion binding;GO:0016597//amino acid binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0016597//amino acid binding;GO:0019787//ubiquitin-like protein transferase activity GO:0007127//meiosis I;GO:0016458//gene silencing;GO:0009968//negative regulation of signal transduction;GO:0016574//histone ubiquitination;GO:0048232//male gamete generation;GO:0019941//modification-dependent protein catabolic process;GO:0071230//cellular response to amino acid stimulus;GO:0007127//meiosis I;GO:0016458//gene silencing;GO:0009968//negative regulation of signal transduction;GO:0016574//histone ubiquitination;GO:0048232//male gamete generation;GO:0019941//modification-dependent protein catabolic process;GO:0071230//cellular response to amino acid stimulus gi|58615693|ref|NP_666190.2|/0/E3 ubiquitin-protein ligase UBR2 isoform 1 [Mus musculus] 320806 3231.79 25.47333333 23.84 -0.095603521 Down 0.248834104 Gfm2 "G elongation factor, mitochondrial 2" K02355|1|0.0|1437|mmu:320806|elongation factor G GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008135//translation factor activity, RNA binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008135//translation factor activity, RNA binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008135//translation factor activity, RNA binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008135//translation factor activity, RNA binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008135//translation factor activity, RNA binding" GO:0009154//purine ribonucleotide catabolic process;GO:0006414//translational elongation;GO:0032988;GO:0009154//purine ribonucleotide catabolic process;GO:0006414//translational elongation;GO:0032988;GO:0009154//purine ribonucleotide catabolic process;GO:0006414//translational elongation;GO:0032988;GO:0009154//purine ribonucleotide catabolic process;GO:0006414//translational elongation;GO:0032988;GO:0009154//purine ribonucleotide catabolic process;GO:0006414//translational elongation;GO:0032988 "gi|225690549|ref|NP_796240.3|/0/ribosome-releasing factor 2, mitochondrial isoform 1 [Mus musculus]" 19713 7319.73 0.766666667 0.536666667 -0.514573173 Down 0.24877769 Ret ret proto-oncogene K05126|1|0.0|2194|mmu:19713|proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane GO:0004713//protein tyrosine kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0046872//metal ion binding;GO:0032550 "GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0072216;GO:0033627//cell adhesion mediated by integrin;GO:0033555//multicellular organismal response to stress;GO:0035295//tube development;GO:0016337//single organismal cell-cell adhesion;GO:0006796//phosphate-containing compound metabolic process;GO:0001667//ameboidal-type cell migration;GO:0006351//transcription, DNA-templated;GO:0006508//proteolysis;GO:0010975//regulation of neuron projection development;GO:0014041//regulation of neuron maturation;GO:0043010//camera-type eye development;GO:0048483//autonomic nervous system development;GO:0016331//morphogenesis of embryonic epithelium;GO:0006464//cellular protein modification process;GO:0021675//nerve development;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0048799;GO:0032526//response to retinoic acid;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0072216;GO:0033627//cell adhesion mediated by integrin;GO:0033555//multicellular organismal response to stress;GO:0035295//tube development;GO:0016337//single organismal cell-cell adhesion;GO:0006796//phosphate-containing compound metabolic process;GO:0001667//ameboidal-type cell migration;GO:0006351//transcription, DNA-templated;GO:0006508//proteolysis;GO:0010975//regulation of neuron projection development;GO:0014041//regulation of neuron maturation;GO:0043010//camera-type eye development;GO:0048483//autonomic nervous system development;GO:0016331//morphogenesis of embryonic epithelium;GO:0006464//cellular protein modification process;GO:0021675//nerve development;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0048799;GO:0032526//response to retinoic acid" "gi|148667176|gb|EDK99592.1|/0/ret proto-oncogene, isoform CRA_b, partial [Mus musculus]" 68275 3058 22.31333333 23.93 0.100914347 Up 0.248683666 Rpa1 replication protein A1 K07466|1|0.0|1150|mmu:68275|replication factor A1 GO:0043234//protein complex;GO:0016604//nuclear body;GO:0000795//synaptonemal complex;GO:0043073//germ cell nucleus;GO:0043234//protein complex;GO:0016604//nuclear body;GO:0000795//synaptonemal complex;GO:0043073//germ cell nucleus GO:0043169//cation binding;GO:0043566//structure-specific DNA binding;GO:0043169//cation binding;GO:0043566//structure-specific DNA binding GO:0048534//hematopoietic or lymphoid organ development;GO:0006996//organelle organization;GO:0006259//DNA metabolic process;GO:0001894//tissue homeostasis;GO:0033554//cellular response to stress;GO:0043009//chordate embryonic development;GO:0022403;GO:0008283//cell proliferation;GO:0048534//hematopoietic or lymphoid organ development;GO:0006996//organelle organization;GO:0006259//DNA metabolic process;GO:0001894//tissue homeostasis;GO:0033554//cellular response to stress;GO:0043009//chordate embryonic development;GO:0022403;GO:0008283//cell proliferation gi|255982530|ref|NP_001157695.1|/0/replication protein A 70 kDa DNA-binding subunit isoform 1 [Mus musculus] 71807 2534.71 22.05333333 23.67333333 0.102266126 Up 0.248683666 Tars2 "threonyl-tRNA synthetase 2, mitochondrial (putative)" K01868|1|0.0|707|mmu:71807|threonyl-tRNA synthetase [EC:6.1.1.3] GO:0044429;GO:0044429;GO:0044429;GO:0044429 GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation "gi|254692873|ref|NP_001157091.1|/0/threonine--tRNA ligase, mitochondrial isoform 4 [Mus musculus] " 230376 3719 0.46 0.683333333 0.570955643 Up 0.248674264 Haus6 "HAUS augmin-like complex, subunit 6" K16589|1|0.0|1772|mmu:230376|HAUS augmin-like complex subunit 6 GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0031981//nuclear lumen - GO:0006461//protein complex assembly;GO:0031023//microtubule organizing center organization;GO:0022402//cell cycle process gi|46559772|ref|NP_775576.2|/0/HAUS augmin-like complex subunit 6 [Mus musculus] 240025 2849 0.686666667 0.463333333 -0.567559454 Down 0.248674264 Dact2 dishevelled-binding antagonist of beta-catenin 2 - - - - - 81601 1999.07 14.90666667 16.04666667 0.106315954 Up 0.248570838 Kat5 K(lysine) acetyltransferase 5 K11304|1|0.0|838|pon:100174410|histone acetyltransferase HTATIP [EC:2.3.1.48] GO:0044427;GO:0035267//NuA4 histone acetyltransferase complex;GO:0044444//cytoplasmic part;GO:0044427;GO:0035267//NuA4 histone acetyltransferase complex;GO:0044444//cytoplasmic part;GO:0044427;GO:0035267//NuA4 histone acetyltransferase complex;GO:0044444//cytoplasmic part;GO:0044427;GO:0035267//NuA4 histone acetyltransferase complex;GO:0044444//cytoplasmic part;GO:0044427;GO:0035267//NuA4 histone acetyltransferase complex;GO:0044444//cytoplasmic part GO:0003712//transcription cofactor activity;GO:0043169//cation binding;GO:0008134//transcription factor binding;GO:0008080//N-acetyltransferase activity;GO:0003712//transcription cofactor activity;GO:0043169//cation binding;GO:0008134//transcription factor binding;GO:0008080//N-acetyltransferase activity;GO:0003712//transcription cofactor activity;GO:0043169//cation binding;GO:0008134//transcription factor binding;GO:0008080//N-acetyltransferase activity;GO:0003712//transcription cofactor activity;GO:0043169//cation binding;GO:0008134//transcription factor binding;GO:0008080//N-acetyltransferase activity;GO:0003712//transcription cofactor activity;GO:0043169//cation binding;GO:0008134//transcription factor binding;GO:0008080//N-acetyltransferase activity "GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0001818//negative regulation of cytokine production;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0016573//histone acetylation;GO:0006281//DNA repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0001818//negative regulation of cytokine production;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0016573//histone acetylation;GO:0006281//DNA repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0001818//negative regulation of cytokine production;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0016573//histone acetylation;GO:0006281//DNA repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0001818//negative regulation of cytokine production;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0016573//histone acetylation;GO:0006281//DNA repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0001818//negative regulation of cytokine production;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0016573//histone acetylation;GO:0006281//DNA repair" gi|947234107|ref|XP_006150009.2|/0/PREDICTED: histone acetyltransferase KAT5 isoform X1 [Tupaia chinensis] 228359 2932.47 14.82666667 15.96333333 0.106567648 Up 0.248570838 Arhgap1 Rho GTPase activating protein 1 K18470|1|0.0|793|mmu:228359|Rho GTPase-activating protein 1 GO:0016020//membrane;GO:0043227//membrane-bounded organelle;GO:0044424;GO:0031252//cell leading edge;GO:0044424;GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0016020//membrane;GO:0043227//membrane-bounded organelle;GO:0044424;GO:0031252//cell leading edge GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction gi|225543424|ref|NP_001139374.1|/0/rho GTPase-activating protein 1 isoform 1 [Mus musculus] 225164 3793 1.083333333 0.823333333 -0.395928676 Down 0.248523826 Mib1 mindbomb E3 ubiquitin protein ligase 1 K10645|1|0.0|2066|mmu:225164|E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27] GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0044327//dendritic spine head;GO:0031982//vesicle;GO:0005635//nuclear envelope GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0007166//cell surface receptor signaling pathway;GO:0001944//vasculature development;GO:0043009//chordate embryonic development;GO:0003143//embryonic heart tube morphogenesis;GO:0006897//endocytosis;GO:0032446//protein modification by small protein conjugation;GO:0009952//anterior/posterior pattern specification;GO:0001838//embryonic epithelial tube formation;GO:0030182//neuron differentiation gi|32189428|ref|NP_659109.2|/0/E3 ubiquitin-protein ligase MIB1 [Mus musculus] 20672 1619 55.36666667 58.97666667 0.091126617 Up 0.248495618 Sox18 SRY (sex determining region Y)-box 18 K09270|1|2e-136|488|mmu:20672|transcription factor SOX7/8/10/18 (SOX group E/F) GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding" GO:0043542//endothelial cell migration;GO:0042127//regulation of cell proliferation;GO:0008544//epidermis development;GO:0006366//transcription from RNA polymerase II promoter;GO:0003160//endocardium morphogenesis;GO:0001885//endothelial cell development;GO:0001708//cell fate specification;GO:0043009//chordate embryonic development;GO:0021700//developmental maturation;GO:0022404//molting cycle process;GO:0001945//lymph vessel development;GO:0048646//anatomical structure formation involved in morphogenesis gi|124244106|ref|NP_033262.2|/1.3397e-135/transcription factor SOX-18 [Mus musculus] 266690 2653 11.44333333 10.54 -0.11863249 Down 0.248486216 Cyb5r4 cytochrome b5 reductase 4 K00326|1|0.0|1045|mmu:266690|cytochrome-b5 reductase [EC:1.6.2.2] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0043169//cation binding;GO:0046906//tetrapyrrole binding;GO:0016653//oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor;GO:0000166//nucleotide binding;GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor" GO:0009636//response to toxic substance;GO:0072593//reactive oxygen species metabolic process;GO:0030154//cell differentiation;GO:0030072//peptide hormone secretion;GO:0046496//nicotinamide nucleotide metabolic process;GO:0033500//carbohydrate homeostasis gi|194328781|ref|NP_077157.2|/0/cytochrome b5 reductase 4 [Mus musculus] 11670 1597 0.37 0.193333333 -0.936434871 Down 0.248448607 Aldh3a1 "aldehyde dehydrogenase family 3, subfamily A1" K00129|1|0.0|915|mmu:11670|aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5] - - - - 100502987 3691 1.133333333 1.42 0.325318684 Up 0.248392192 Gm17066 predicted gene 17066 - - - - gi|90079133|dbj|BAE89246.1|/7.51898e-16/unnamed protein product [Macaca fascicularis] 319446 1721 1.026666667 1.306666667 0.347923303 Up 0.24834518 Dpep2 dipeptidase 2 K01273|1|0.0|776|mmu:319446|membrane dipeptidase [EC:3.4.13.19] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity;GO:0043169//cation binding;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity;GO:0043169//cation binding;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity;GO:0043169//cation binding GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process gi|74140405|dbj|BAE42354.1|/0/unnamed protein product [Mus musculus] 71673 1953 7.936666667 8.69 0.130822962 Up 0.248316973 Rnf215 ring finger protein 215 K16273|1|1e-15|87.8|crg:105333951|E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27];K15694|2|3e-14|83.2|mmu:207742|RING finger protein 43 [EC:2.3.2.27] GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding - "gi|148708514|gb|EDL40461.1|/0/RIKEN cDNA 0610009J22, isoform CRA_b, partial [Mus musculus]" 67661 5440 8.573333333 7.826666667 -0.131458234 Down 0.248316973 Ift172 intraflagellar transport 172 K19676|1|0.0|3392|mmu:67661|intraflagellar transport protein 172 GO:0005815//microtubule organizing center;GO:0005929//cilium GO:0005515//protein binding GO:0003002//regionalization;GO:0021515//cell differentiation in spinal cord;GO:0010927;GO:0001838//embryonic epithelial tube formation;GO:0051604//protein maturation;GO:0007166//cell surface receptor signaling pathway;GO:0009855//determination of bilateral symmetry "gi|148705414|gb|EDL37361.1|/0/intraflagellar transport 172 homolog (Chlamydomonas), isoform CRA_a, partial [Mus musculus]" 21804 3889.71 8.073333333 8.826666667 0.128704257 Up 0.248316973 Tgfb1i1 transforming growth factor beta 1 induced transcript 1 K05760|1|3e-97|359|tru:101070146|paxillin GO:0005924//cell-substrate adherens junction;GO:0043229//intracellular organelle;GO:0005924//cell-substrate adherens junction;GO:0005622//intracellular;GO:0043231//intracellular membrane-bounded organelle;GO:0005924//cell-substrate adherens junction;GO:0043232;GO:0005924//cell-substrate adherens junction;GO:0005634//nucleus GO:0003712//transcription cofactor activity;GO:0035258//steroid hormone receptor binding;GO:0046332//SMAD binding;GO:0003712//transcription cofactor activity;GO:0035258//steroid hormone receptor binding;GO:0046332//SMAD binding;GO:0046914//transition metal ion binding;GO:0035258//steroid hormone receptor binding;GO:0046332//SMAD binding;GO:0003712//transcription cofactor activity;GO:0046872//metal ion binding;GO:0035258//steroid hormone receptor binding;GO:0046332//SMAD binding "GO:0006351//transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001837//epithelial to mesenchymal transition;GO:0008283//cell proliferation;GO:0045444//fat cell differentiation;GO:0022610;GO:0002009//morphogenesis of an epithelium;GO:0006950//response to stress;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001837//epithelial to mesenchymal transition;GO:0008283//cell proliferation;GO:0022610;GO:0006950//response to stress;GO:0060429//epithelium development;GO:0006351//transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001837//epithelial to mesenchymal transition;GO:0045444//fat cell differentiation;GO:0002009//morphogenesis of an epithelium;GO:0006950//response to stress;GO:0006351//transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001837//epithelial to mesenchymal transition;GO:0045444//fat cell differentiation;GO:0002009//morphogenesis of an epithelium;GO:0006950//response to stress" gi|575501561|ref|NP_001276479.1|/0/transforming growth factor beta-1-induced transcript 1 protein isoform a [Mus musculus] 217664 2620 8.18 8.93 0.126559332 Up 0.248316973 Mgat2 mannoside acetylglucosaminyltransferase 2 "K00736|1|0.0|925|mmu:217664|alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.143]" - - - - 53310 3410.48 1.933333333 1.606666667 -0.267019754 Down 0.248307571 Dlg3 "discs, large homolog 3 (Drosophila)" K12075|1|0.0|687|ecb:100146394|discs large protein 2/3 GO:0043296//apical junction complex;GO:0044297//cell body;GO:0044327//dendritic spine head;GO:0008328//ionotropic glutamate receptor complex;GO:0044424;GO:0043296//apical junction complex;GO:0044297//cell body;GO:0044327//dendritic spine head;GO:0008328//ionotropic glutamate receptor complex;GO:0044424;GO:0008328//ionotropic glutamate receptor complex;GO:0044327//dendritic spine head;GO:0043296//apical junction complex;GO:0044297//cell body;GO:0044424;GO:0043296//apical junction complex;GO:0030425//dendrite;GO:0044297//cell body;GO:0044424;GO:0016020//membrane "GO:0044389//ubiquitin-like protein ligase binding;GO:0019902//phosphatase binding;GO:0035254//glutamate receptor binding;GO:0019904//protein domain specific binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0019902//phosphatase binding;GO:0035254//glutamate receptor binding;GO:0019904//protein domain specific binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0019904//protein domain specific binding;GO:0019902//phosphatase binding;GO:0035254//glutamate receptor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0044389//ubiquitin-like protein ligase binding;GO:0019902//phosphatase binding;GO:0035254//glutamate receptor binding;GO:0019904//protein domain specific binding" GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0001738//morphogenesis of a polarized epithelium;GO:0010921//regulation of phosphatase activity;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0010921//regulation of phosphatase activity;GO:0007267//cell-cell signaling;GO:0008283//cell proliferation;GO:0010921//regulation of phosphatase activity;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0006935//chemotaxis;GO:0001738//morphogenesis of a polarized epithelium;GO:0007267//cell-cell signaling;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0006935//chemotaxis;GO:0008283//cell proliferation;GO:0010921//regulation of phosphatase activity gi|28972680|dbj|BAC65756.1|/0/mKIAA1232 protein [Mus musculus] 72151 1750 1.603333333 1.933333333 0.270016006 Up 0.248307571 Rfc5 replication factor C (activator 1) 5 K10756|1|2e-180|635|mmu:72151|replication factor C subunit 3/5 GO:0005657//replication fork;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0016462//pyrophosphatase activity;GO:0032550 GO:0006259//DNA metabolic process gi|110625924|ref|NP_082404.1|/1.28089e-179/replication factor C subunit 5 [Mus musculus] 26434 2680.3 1.933333333 1.6 -0.273018494 Down 0.248307571 Prnd prion protein dublet - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0030003//cellular cation homeostasis;GO:0051259//protein oligomerization;GO:0030003//cellular cation homeostasis;GO:0051259//protein oligomerization;GO:0030003//cellular cation homeostasis;GO:0051259//protein oligomerization;GO:0030003//cellular cation homeostasis;GO:0051259//protein oligomerization gi|506326690|ref|NP_001265187.1|/2.42743e-102/prion protein gene complex [Mus musculus] 24136 9125.96 1.95 1.616666667 -0.270451877 Down 0.248307571 Zeb2 zinc finger E-box binding homeobox 2 K09299|1|0.0|2161|mmu:24136|zinc finger homeobox protein 1/2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046332//SMAD binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046332//SMAD binding "GO:0006351//transcription, DNA-templated;GO:0014020;GO:0016055//Wnt signaling pathway;GO:0021543//pallium development;GO:0043406//positive regulation of MAP kinase activity;GO:0009952//anterior/posterior pattern specification;GO:0006351//transcription, DNA-templated;GO:0014020;GO:0016055//Wnt signaling pathway;GO:0021543//pallium development;GO:0043406//positive regulation of MAP kinase activity;GO:0009952//anterior/posterior pattern specification" gi|28972281|dbj|BAC65594.1|/0/mKIAA0569 protein [Mus musculus] 107993 1570 0.38 0.59 0.634715536 Up 0.248157133 Bfsp2 "beaded filament structural protein 2, phakinin" K10379|1|0.0|805|mmu:107993|phakinin GO:0043234//protein complex;GO:0043232;GO:0016020//membrane GO:0005488//binding;GO:0005198//structural molecule activity GO:0048468//cell development;GO:0050953//sensory perception of light stimulus;GO:0007010//cytoskeleton organization;GO:0021700//developmental maturation "gi|148689126|gb|EDL21073.1|/0/beaded filament structural protein 2, phakinin, isoform CRA_a [Mus musculus]" 68865 1165 0.936666667 1.21 0.369399418 Up 0.248110121 Arv1 "ARV1 homolog, fatty acid homeostasis modulator" K02998|1|1e-13|79.7|tsp:Tsp_00726|small subunit ribosomal protein SAe - - - - 73453 1084 0.283333333 0.126666667 -1.161463423 Down 0.248100718 1700067K01Rik RIKEN cDNA 1700067K01 gene - - - - gi|148678976|gb|EDL10923.1|/5.01672e-156/RIKEN cDNA 1700067K01 [Mus musculus] 14202 2670 0.296666667 0.133333333 -1.153805336 Down 0.248025499 Fhl4 four and a half LIM domains 4 K14365|1|3e-133|478|oas:100307044|four and a half LIM domains protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0016049//cell growth;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006813//potassium ion transport;GO:0032412//regulation of ion transmembrane transporter activity;GO:1901991//negative regulation of mitotic cell cycle phase transition gi|31560590|ref|NP_034344.2|/1.26357e-179/four and a half LIM domains 4 [Mus musculus] 225280 2360 10.41 11.30333333 0.118778215 Up 0.247922073 Ino80c INO80 complex subunit C K11667|1|3e-91|338|mmu:225280|INO80 complex subunit C GO:0044665//MLL1/2 complex;GO:0000790//nuclear chromatin - "GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006351//transcription, DNA-templated" gi|27369894|ref|NP_766213.1|/2.759e-90/INO80 complex subunit C [Mus musculus] 237253 3442 1.493333333 1.81 0.277453466 Up 0.247818647 Lrp11 low density lipoprotein receptor-related protein 11 K15619|1|1e-35|155|pss:102452161|Kunitz-type protease inhibitor 1 GO:0031224//intrinsic component of membrane - GO:0016192//vesicle-mediated transport gi|31542055|ref|NP_766372.1|/0/low-density lipoprotein receptor-related protein 11 precursor [Mus musculus] 66399 1180 24.03 22.46 -0.097478721 Down 0.247781037 Tsfm "Ts translation elongation factor, mitochondrial" K02357|1|4e-175|616|mmu:66399|elongation factor Ts GO:0043231//intracellular membrane-bounded organelle - GO:0006412//translation "gi|148692513|gb|EDL24460.1|/3.42913e-177/Ts translation elongation factor, mitochondrial, isoform CRA_b [Mus musculus]" 13358 1695 3.973333333 4.476666667 0.172075069 Up 0.24775283 Slc25a1 "solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1" "K15100|1|6e-144|513|mmu:13358|solute carrier family 25 (mitochondrial citrate transporter), member 1" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0015142//tricarboxylic acid transmembrane transporter activity GO:0006839//mitochondrial transport;GO:0035336//long-chain fatty-acyl-CoA metabolic process;GO:0006641//triglyceride metabolic process;GO:0006006//glucose metabolic process "gi|23943838|ref|NP_694790.1|/5.37538e-143/tricarboxylate transport protein, mitochondrial [Mus musculus]" 15159 2383 15.38666667 14.27 -0.108695388 Down 0.247734025 Hccs holocytochrome c synthetase K01764|1|1e-155|552|mmu:15159|cytochrome c heme-lyase [EC:4.4.1.17] GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0016846//carbon-sulfur lyase activity;GO:0043169//cation binding - gi|225543251|ref|NP_032248.3|/1.22571e-154/cytochrome c-type heme lyase [Mus musculus] 19336 1865 13.72 14.84333333 0.11353463 Up 0.247734025 Rab24 "RAB24, member RAS oncogene family" K07912|1|2e-104|382|ngi:103732360|Ras-related protein Rab-24 GO:0005773//vacuole GO:0032550 GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization;GO:0044248 gi|568983176|ref|XP_006517228.1|/1.33144e-122/PREDICTED: ras-related protein Rab-24 isoform X1 [Mus musculus] 76469 11850 53.99 50.60666667 -0.093364766 Down 0.247602392 Cmya5 cardiomyopathy associated 5 K08285|1|6e-25|121|bfo:BRAFLDRAFT_125602|midline 1 [EC:2.3.2.27];K14721|3|1e-22|114|phu:Phum_PHUM540970|DNA-directed RNA polymerase III subunit RPC5 - - - gi|256773195|ref|NP_076310.2|/0/cardiomyopathy-associated protein 5 [Mus musculus] 72948 5108 4.013333333 3.54 -0.181051626 Down 0.24759299 Tppp tubulin polymerization promoting protein K20027|1|5e-27|127|nle:100594932|palmitoyltransferase ZDHHC1/11 [EC:2.3.1.225] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding GO:0031109//microtubule polymerization or depolymerization;GO:0031334//positive regulation of protein complex assembly gi|33469051|ref|NP_878259.1|/9.13048e-108/tubulin polymerization-promoting protein [Mus musculus] 19250 10766 4.11 3.636666667 -0.176521698 Down 0.24759299 Ptpn14 "protein tyrosine phosphatase, non-receptor type 14" K18025|1|0.0|2234|mmu:19250|tyrosine-protein phosphatase non-receptor type 14/21 [EC:3.1.3.48] GO:0043231//intracellular membrane-bounded organelle;GO:0043232 "GO:0000989//transcription factor activity, transcription factor binding;GO:0005102//receptor binding;GO:0004721//phosphoprotein phosphatase activity" GO:0006470//protein dephosphorylation;GO:0006611//protein export from nucleus;GO:0009653//anatomical structure morphogenesis;GO:0008283//cell proliferation gi|110825986|ref|NP_033002.2|/0/tyrosine-protein phosphatase non-receptor type 14 [Mus musculus] 55989 1976 3.89 3.423333333 -0.184368379 Down 0.24759299 Nop58 NOP58 ribonucleoprotein K14565|1|0.0|815|mmu:55989|nucleolar protein 58 GO:0016604//nuclear body;GO:0030529//intracellular ribonucleoprotein complex GO:0008173//RNA methyltransferase activity;GO:0003723//RNA binding;GO:0043021//ribonucleoprotein complex binding;GO:0005515//protein binding GO:0000154//rRNA modification;GO:0006606//protein import into nucleus gi|120407050|ref|NP_061356.2|/0/nucleolar protein 58 [Mus musculus] 77591 3368 1.586666667 1.283333333 -0.306103128 Down 0.247545978 Ddx10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 K14776|1|0.0|1502|mmu:77591|ATP-dependent RNA helicase DDX10/DBP4 [EC:3.6.4.13] - - - - 20826 1257 53.66 57.00666667 0.087283591 Up 0.247489563 Nhp2l1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) K12845|1|4e-48|194|mdo:100028876|U4/U6 small nuclear ribonucleoprotein SNU13 - - - - 626832 3788 0.846666667 1.11 0.39069368 Up 0.247489563 Gm6710 predicted gene 6710 K09228|1|0.0|1219|mmu:626832|KRAB domain-containing zinc finger protein - - - "gi|150010536|ref|NP_001092778.1|/0/KRAB box and zinc finger, C2H2 type domain containing isoform 1 [Mus musculus]" 67429 3444 1.083333333 0.826666667 -0.390099598 Down 0.247489563 Nudcd1 NudC domain containing 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - "gi|148676798|gb|EDL08745.1|/0/NudC domain containing 1, isoform CRA_a, partial [Mus musculus]" 12043 7209 0.86 1.123333333 0.385377526 Up 0.247489563 Bcl2 B cell leukemia/lymphoma 2 K02161|1|4e-115|420|mmu:12043|apoptosis regulator Bcl-2 GO:0031966//mitochondrial membrane;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane GO:0051400//BH domain binding;GO:0019903//protein phosphatase binding;GO:0042802//identical protein binding;GO:0022803//passive transmembrane transporter activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0046983//protein dimerization activity;GO:0003677//DNA binding "GO:0001894//tissue homeostasis;GO:0014074//response to purine-containing compound;GO:0034976//response to endoplasmic reticulum stress;GO:0046683//response to organophosphorus;GO:0001934//positive regulation of protein phosphorylation;GO:0035264//multicellular organism growth;GO:0008585//female gonad development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0051384//response to glucocorticoid;GO:0016567//protein ubiquitination;GO:0007409//axonogenesis;GO:0019079//viral genome replication;GO:0001503//ossification;GO:0030183//B cell differentiation;GO:0003008;GO:0001942//hair follicle development;GO:0030036//actin cytoskeleton organization;GO:0007281//germ cell development;GO:0043434//response to peptide hormone;GO:0010720//positive regulation of cell development;GO:0050851//antigen receptor-mediated signaling pathway;GO:0007423//sensory organ development;GO:0097305//response to alcohol;GO:0043066//negative regulation of apoptotic process;GO:0001822//kidney development;GO:0016050//vesicle organization;GO:0010212//response to ionizing radiation;GO:0008637//apoptotic mitochondrial changes;GO:0019740//nitrogen utilization;GO:0070997//neuron death;GO:0008285//negative regulation of cell proliferation;GO:0002209//behavioral defense response;GO:0007044//cell-substrate junction assembly;GO:0002252;GO:0019748//secondary metabolic process;GO:0042391//regulation of membrane potential;GO:0030888//regulation of B cell proliferation;GO:0032845;GO:0010608//posttranscriptional regulation of gene expression;GO:0021548//pons development;GO:0043369//CD4-positive or CD8-positive, alpha-beta T cell lineage commitment;GO:0006839//mitochondrial transport;GO:0048754//branching morphogenesis of an epithelial tube;GO:0009101//glycoprotein biosynthetic process;GO:0044772//mitotic cell cycle phase transition;GO:0007568//aging;GO:0008104//protein localization;GO:0030318//melanocyte differentiation;GO:0043393//regulation of protein binding;GO:0009968//negative regulation of signal transduction;GO:0009411//response to UV;GO:0016049//cell growth;GO:0033273//response to vitamin;GO:0010038//response to metal ion;GO:0002260//lymphocyte homeostasis;GO:0007160//cell-matrix adhesion;GO:0032409;GO:0014041//regulation of neuron maturation;GO:0044093;GO:0000302//response to reactive oxygen species;GO:0014909//smooth muscle cell migration;GO:0010522//regulation of calcium ion transport into cytosol" gi|589962382|ref|XP_006993748.1|/1.38321e-109/PREDICTED: apoptosis regulator Bcl-2 [Peromyscus maniculatus bairdii] 234878 5692 0.59 0.383333333 -0.622115499 Down 0.247489563 BC021891 cDNA sequence BC021891 K17534|1|0.0|1591|mmu:234878|mitogen-activated protein kinase kinase kinase MLK4 [EC:2.7.11.25] - - GO:0006468//protein phosphorylation gi|119637821|ref|NP_663583.2|/0/mitogen-activated protein kinase kinase kinase MLK4 [Mus musculus] 381921 5110.25 22.95666667 21.40666667 -0.100853012 Down 0.247442551 Taok2 TAO kinase 2 K04429|1|0.0|1858|mmu:381921|thousand and one amino acid protein kinase [EC:2.7.11.1] GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0031988//membrane-bounded vesicle;GO:0043232 GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0019901//protein kinase binding GO:0032872//regulation of stress-activated MAPK cascade;GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis;GO:0007044//cell-substrate junction assembly;GO:0007254//JNK cascade;GO:0006468//protein phosphorylation;GO:0000077//DNA damage checkpoint gi|255003684|ref|NP_001157247.1|/0/serine/threonine-protein kinase TAO2 isoform 2 [Mus musculus] 20917 3447 50.26333333 53.58 0.092188231 Up 0.247423747 Suclg2 "succinate-Coenzyme A ligase, GDP-forming, beta subunit" K01900|1|0.0|769|mmu:20917|succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5] GO:0030062//mitochondrial tricarboxylic acid cycle enzyme complex GO:0004774//succinate-CoA ligase activity;GO:0043169//cation binding;GO:0032550;GO:0046983//protein dimerization activity GO:0043648//dicarboxylic acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0009060//aerobic respiration "gi|165972309|ref|NP_035637.2|/0/succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial precursor [Mus musculus]" 93687 2013 52.83 49.50666667 -0.093734595 Down 0.247423747 Csnk1a1 "casein kinase 1, alpha 1" "K08957|1|4e-164|580|dre:192307|casein kinase 1, alpha [EC:2.7.11.1]" GO:0005815//microtubule organizing center;GO:0016604//nuclear body;GO:0005849//mRNA cleavage factor complex;GO:0000776//kinetochore;GO:0044444//cytoplasmic part GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0033218//amide binding GO:0006468//protein phosphorylation;GO:0032989;GO:0000087//mitotic M phase;GO:0007166//cell surface receptor signaling pathway "gi|148677819|gb|EDL09766.1|/8.13128e-173/casein kinase 1, alpha 1, isoform CRA_d, partial [Mus musculus]" 11658 4979 0.26 0.453333333 0.802060622 Up 0.24739554 Alcam activated leukocyte cell adhesion molecule K06547|1|0.0|1106|mmu:11658|activated leukocyte cell adhesion molecule - - - - 56320 2913.99 8.26 7.523333333 -0.134769769 Down 0.247367332 Dbn1 drebrin 1 K20520|1|1e-80|303|tgu:100224486|drebrin-like protein GO:0005911//cell-cell junction;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0005911//cell-cell junction;GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0005911//cell-cell junction;GO:0005856//cytoskeleton;GO:0016020//membrane GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0048731//system development;GO:0030036//actin cytoskeleton organization;GO:0007154//cell communication;GO:0034613//cellular protein localization;GO:0048731//system development;GO:0048869//cellular developmental process;GO:0030036//actin cytoskeleton organization;GO:0007154//cell communication;GO:0034613//cellular protein localization;GO:0048731//system development;GO:0048869//cellular developmental process;GO:0030036//actin cytoskeleton organization;GO:0007154//cell communication;GO:0034613//cellular protein localization "gi|148709252|gb|EDL41198.1|/0/drebrin 1, isoform CRA_a, partial [Mus musculus]" 230784 2677 2.11 2.48 0.233097122 Up 0.24735793 Sesn2 sestrin 2 K20394|1|0.0|946|mmu:230784|sestrin 2 GO:0044424 - GO:0022402//cell cycle process gi|21450289|ref|NP_659156.1|/0/sestrin-2 [Mus musculus] 140858 2916 14.02 15.12666667 0.109607759 Up 0.24732032 Wdr5 WD repeat domain 5 K14963|1|0.0|666|mcc:722123|COMPASS component SWD3 GO:0044665//MLL1/2 complex;GO:0000123//histone acetyltransferase complex GO:0042393//histone binding;GO:0010485//H4 histone acetyltransferase activity;GO:0018024//histone-lysine N-methyltransferase activity "GO:0048731//system development;GO:0006351//transcription, DNA-templated;GO:0043967//histone H4 acetylation;GO:0034968//histone lysine methylation" gi|831234449|ref|XP_003794910.2|/0/PREDICTED: WD repeat-containing protein 5 [Otolemur garnettii] 21923 7100 0.263333333 0.456666667 0.794251335 Up 0.247254504 Tnc tenascin C K06252|1|0.0|4105|mmu:21923|tenascin GO:0005578//proteinaceous extracellular matrix GO:0005515//protein binding GO:0048741//skeletal muscle fiber development;GO:0007155//cell adhesion;GO:0010467//gene expression;GO:0033280//response to vitamin D;GO:0032526//response to retinoic acid;GO:0008283//cell proliferation;GO:0042476//odontogenesis;GO:0030850//prostate gland development;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0031103//axon regeneration;GO:0071379//cellular response to prostaglandin stimulus gi|126722834|ref|NP_035737.2|/0/tenascin precursor [Mus musculus] 226525 10046 3.616666667 3.173333333 -0.188661564 Down 0.247254504 Rasal2 RAS protein activator like 2 K17633|1|0.0|2326|mmu:226525|RAS protein activator-like 2 - - - gi|226958516|ref|NP_808312.3|/0/ras GTPase-activating protein nGAP [Mus musculus] 21416 4125.68 3.19 3.626666667 0.185087727 Up 0.247254504 Tcf7l2 "transcription factor 7 like 2, T cell specific, HMG box" K04491|1|0.0|678|ssc:100153922|transcription factor 7-like 2 - - - gi|218931192|ref|NP_001136394.1|/0/transcription factor 7-like 2 isoform 6 [Mus musculus] 319454 1175 0.05 0.19 1.925999419 Up 0.247245101 Rptoros "regulatory associated protein of MTOR, complex 1, opposite strand" K07204|1|6e-10|67.8|myb:102240594|regulatory associated protein of mTOR - - - - 27371 4734 0.133333333 0.29 1.121015401 Up 0.247075858 Sh2d2a SH2 domain containing 2A K08273|1|0.0|736|mmu:27371|SH2 domain protein 2A GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0044424 GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding GO:0042110//T cell activation;GO:0007165//signal transduction;GO:0042110//T cell activation;GO:0007165//signal transduction gi|70909334|ref|NP_001020742.1|/0/SH2 domain-containing protein 2A isoform 2 [Mus musculus] 72313 11488 3.266666667 2.85 -0.196857329 Down 0.246972432 Fryl FRY like transcription coactivator - - - - - 21856 1798 53.67333333 50.47666667 -0.088588846 Down 0.246906616 Timm44 translocase of inner mitochondrial membrane 44 K17804|1|0.0|891|mmu:21856|mitochondrial import inner membrane translocase subunit TIM44 GO:0005743//mitochondrial inner membrane GO:0032550;GO:0008320//protein transmembrane transporter activity;GO:0005515//protein binding GO:0006605//protein targeting;GO:0019538//protein metabolic process gi|170763467|ref|NP_035722.2|/0/mitochondrial import inner membrane translocase subunit TIM44 [Mus musculus] 18744 2541.38 11.04 10.17 -0.118420493 Down 0.246906616 Pja1 "praja ring finger 1, E3 ubiquitin protein ligase" K10633|1|2e-160|568|rno:683077|E3 ubiquitin-protein ligase Praja1 [EC:2.3.2.27] GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046872//metal ion binding;GO:0003824//catalytic activity;GO:0046872//metal ion binding;GO:0003824//catalytic activity GO:0009057//macromolecule catabolic process;GO:0032446//protein modification by small protein conjugation;GO:0009057//macromolecule catabolic process;GO:0032446//protein modification by small protein conjugation;GO:0009057//macromolecule catabolic process;GO:0032446//protein modification by small protein conjugation;GO:0009057//macromolecule catabolic process;GO:0032446//protein modification by small protein conjugation gi|594542497|ref|NP_001277484.1|/0/E3 ubiquitin-protein ligase Praja-1 isoform 3 [Mus musculus] 66089 1946 9.65 10.52333333 0.124990912 Up 0.246906616 Rmnd5b required for meiotic nuclear division 5 homolog B K18624|1|5e-21|105|nve:NEMVE_v1g194411|macrophage erythroblast attacher - - - gi|795237633|ref|XP_011808297.1|/0/PREDICTED: protein RMD5 homolog B isoform X1 [Colobus angolensis palliatus] 68566 982 0.01 0.106666667 3.415037499 Up 0.246840799 Caly calcyon neuron-specific vesicular protein K15493|1|8e-116|419|mmu:68566|neuron-specific vesicular protein calcyon GO:0016021//integral component of membrane;GO:0012506//vesicle membrane;GO:0016021//integral component of membrane;GO:0012506//vesicle membrane;GO:0016021//integral component of membrane;GO:0012506//vesicle membrane GO:0030276//clathrin binding;GO:0001664//G-protein coupled receptor binding;GO:0030276//clathrin binding;GO:0001664//G-protein coupled receptor binding;GO:0030276//clathrin binding;GO:0001664//G-protein coupled receptor binding GO:0006901//vesicle coating;GO:0006897//endocytosis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006901//vesicle coating;GO:0006897//endocytosis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006901//vesicle coating;GO:0006897//endocytosis;GO:0007186//G-protein coupled receptor signaling pathway "gi|148685949|gb|EDL17896.1|/8.40862e-120/dopamine receptor D1 interacting protein, isoform CRA_b, partial [Mus musculus]" 100316677 119 0.106666667 0.01 -3.415037499 Down 0.246840799 Mir1199 microRNA 1199 - - - - - 70081 2221 0.01 0.106666667 3.415037499 Up 0.246840799 2210404O09Rik zinc finger protein 995 K09228|1|0.0|871|mmu:210853|KRAB domain-containing zinc finger protein - - - gi|374532771|ref|NP_001243422.1|/0/uncharacterized protein LOC70081 [Mus musculus] 436440 960 0.106666667 0.01 -3.415037499 Down 0.246840799 Gpr31b "G protein-coupled receptor 31, D17Leh66b region" K08406|1|4e-171|602|mmu:436440|G protein-coupled receptor 31 GO:0016021//integral component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway "gi|130505520|ref|NP_001013854.2|/2.92982e-170/12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor [Mus musculus]" 14699 963 0.01 0.106666667 3.415037499 Up 0.246840799 Gngt1 "guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1" K04548|1|1e-35|152|cge:100760746|guanine nucleotide-binding protein G(T) subunit gamma-T1 GO:0031513//nonmotile primary cilium;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane GO:0017111//nucleoside-triphosphatase activity;GO:0060089 GO:0033036;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0001666//response to hypoxia;GO:0009154//purine ribonucleotide catabolic process;GO:0010658;GO:0001754//eye photoreceptor cell differentiation gi|33563258|ref|NP_034444.1|/1.04746e-34/guanine nucleotide-binding protein G(T) subunit gamma-T1 precursor [Mus musculus] 100628600 93 0.106666667 0.01 -3.415037499 Down 0.246840799 Mir5131 microRNA 5131 - - - - - 80751 1980 22.61666667 21.09666667 -0.100371248 Down 0.246831396 Rnf34 ring finger protein 34 K18592|1|3e-28|129|sko:100372526|gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14];K16061|3|3e-09|66.2|clv:102090095|baculoviral IAP repeat-containing protein 7/8;K10641|4|4e-09|65.9|tad:TRIADDRAFT_53391|E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27];K04725|5|7e-09|65.1|acs:100557644|E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27] GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0012501//programmed cell death gi|13385490|ref|NP_085041.1|/1.66293e-170/E3 ubiquitin-protein ligase RNF34 [Mus musculus] 13496 5355.07 0.883333333 0.646666667 -0.449935707 Down 0.246774982 Arid3a AT rich interactive domain 3A (BRIGHT-like) K14829|1|3e-88|330|clv:102091091|pre-rRNA-processing protein IPI3;K11653|4|1e-21|108|cfa:484047|AT-rich interactive domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044425;GO:0043231//intracellular membrane-bounded organelle;GO:0044425;GO:0043231//intracellular membrane-bounded organelle;GO:0044425 GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter "gi|148699676|gb|EDL31623.1|/0/AT rich interactive domain 3A (Bright like), isoform CRA_b, partial [Mus musculus]" 93888 3284 0.963333333 1.236666667 0.360349694 Up 0.24676558 Pcdhb17 protocadherin beta 17 K16494|1|0.0|1427|mmu:93888|protocadherin beta GO:0031224//intrinsic component of membrane - GO:0022610 gi|28972798|dbj|BAC65815.1|/0/mKIAA1621 protein [Mus musculus] 11861 3680.39 5.183333333 5.766666667 0.153857458 Up 0.246756177 Arl4a ADP-ribosylation factor-like 4A K07945|1|5e-107|373|pps:100985091|ADP-ribosylation factor-like protein 4 GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0045444//fat cell differentiation;GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0045444//fat cell differentiation "gi|440894615|gb|ELR47022.1|/2.88095e-108/ADP-ribosylation factor-like protein 4A, partial [Bos mutus]" 20017 4017 6.066666667 5.483333333 -0.145850866 Down 0.246756177 Polr1b polymerase (RNA) I polypeptide B K03002|1|0.0|2288|mmu:20017|DNA-directed RNA polymerase I subunit RPA2 [EC:2.7.7.6] GO:0044452//nucleolar part GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity;GO:0001882//nucleoside binding "GO:0007000//nucleolus organization;GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organism development" gi|224967092|ref|NP_033112.2|/0/DNA-directed RNA polymerase I subunit RPA2 [Mus musculus] 230917 3658.41 49.73666667 52.89666667 0.088866991 Up 0.246699763 Tmem201 transmembrane protein 201 - GO:0016020//membrane - - gi|546231934|ref|NP_001271199.1|/0/transmembrane protein 201 isoform c [Mus musculus] 664968 1051 2.526666667 2.923333333 0.210378994 Up 0.246690361 Tmem238 transmembrane protein 238 - - - - "gi|148699313|gb|EDL31260.1|/4.14642e-59/mCG53437, isoform CRA_b, partial [Mus musculus]" 52184 2293.98 1.05 1.333333333 0.344648171 Up 0.246671556 Odf2l outer dense fiber of sperm tails 2-like K16479|1|1e-115|420|mdo:100617972|outer dense fiber protein 2 GO:0005815//microtubule organizing center - - gi|244793559|ref|NP_079990.2|/0/outer dense fiber protein 2-like isoform 2 [Mus musculus] 67763 1868 13.32 14.41 0.113476253 Up 0.246615142 Prpsap1 phosphoribosyl pyrophosphate synthetase-associated protein 1 K00948|1|6e-66|254|tad:TRIADDRAFT_25357|ribose-phosphate pyrophosphokinase [EC:2.7.6.1] GO:0043234//protein complex GO:0046872//metal ion binding;GO:0016778;GO:0030234//enzyme regulator activity;GO:0019899//enzyme binding GO:0009117//nucleotide metabolic process;GO:0043549//regulation of kinase activity gi|332260160|ref|XP_003279153.1|/0/PREDICTED: phosphoribosyl pyrophosphate synthase-associated protein 1 isoform X1 [Nomascus leucogenys] 68366 2259 13.52 14.61 0.111861027 Up 0.246615142 Tmem129 transmembrane protein 129 K18710|1|7e-128|460|myb:102253882|histone RNA hairpin-binding protein GO:0031224//intrinsic component of membrane - - gi|73853456|ref|NP_080974.2|/0/E3 ubiquitin-protein ligase TM129 [Mus musculus] 101206 1855 14.35 15.44333333 0.105933445 Up 0.246615142 Tada3 transcriptional adaptor 3 K11315|1|0.0|761|mmu:101206|transcriptional adapter 3 GO:0070461//SAGA-type complex;GO:0005667//transcription factor complex;GO:0005819//spindle GO:0005102//receptor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003713//transcription coactivator activity;GO:0008080//N-acetyltransferase activity GO:0006366//transcription from RNA polymerase II promoter;GO:0090311//regulation of protein deacetylation;GO:0016575//histone deacetylation;GO:0006468//protein phosphorylation;GO:0010608//posttranscriptional regulation of gene expression;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0000087//mitotic M phase;GO:0016573//histone acetylation "gi|148667039|gb|EDK99455.1|/0/transcriptional adaptor 3 (NGG1 homolog, yeast)-like, isoform CRA_c, partial [Mus musculus]" 236732 3246.74 14.32666667 15.41666667 0.105787883 Up 0.246615142 Rbm10 RNA binding motif protein 10 K13094|1|0.0|1410|rno:64510|RNA-binding protein 5/10 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0036094//small molecule binding GO:0048255//mRNA stabilization;GO:0008283//cell proliferation;GO:0010661;GO:0048255//mRNA stabilization;GO:0008283//cell proliferation;GO:0010661;GO:0010661;GO:0048255//mRNA stabilization;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter gi|625190261|ref|XP_007634676.1|/0/PREDICTED: RNA-binding protein 10 isoform X3 [Cricetulus griseus] 26908 1801 14.81 13.72333333 -0.109940693 Down 0.246615142 Eif2s3y "eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked" K03242|1|0.0|930|mmu:26908|translation initiation factor 2 subunit 3 GO:0044444//cytoplasmic part "GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008135//translation factor activity, RNA binding" GO:0006412//translation;GO:0009154//purine ribonucleotide catabolic process "gi|7242148|ref|NP_036141.1|/0/eukaryotic translation initiation factor 2 subunit 3, Y-linked [Mus musculus]" 19056 3844.08 15.00666667 13.92 -0.108444345 Down 0.246615142 Ppp3cb "protein phosphatase 3, catalytic subunit, beta isoform" K04348|1|0.0|1007|mmu:19056|serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16] GO:0008287//protein serine/threonine phosphatase complex;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0008287//protein serine/threonine phosphatase complex;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0008287//protein serine/threonine phosphatase complex;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0046872//metal ion binding;GO:0019903//protein phosphatase binding;GO:0004723//calcium-dependent protein serine/threonine phosphatase activity;GO:0046983//protein dimerization activity;GO:0046872//metal ion binding;GO:0019903//protein phosphatase binding;GO:0004723//calcium-dependent protein serine/threonine phosphatase activity;GO:0046983//protein dimerization activity;GO:0046872//metal ion binding;GO:0019903//protein phosphatase binding;GO:0004723//calcium-dependent protein serine/threonine phosphatase activity;GO:0046983//protein dimerization activity "GO:0019725//cellular homeostasis;GO:0032024//positive regulation of insulin secretion;GO:0050804//modulation of synaptic transmission;GO:0030098//lymphocyte differentiation;GO:0002260//lymphocyte homeostasis;GO:0014075//response to amine;GO:0006887//exocytosis;GO:0006796//phosphate-containing compound metabolic process;GO:0006351//transcription, DNA-templated;GO:0051705;GO:0007611//learning or memory;GO:0007409//axonogenesis;GO:0001911;GO:0006464//cellular protein modification process;GO:0042493//response to drug;GO:0042110//T cell activation;GO:0019725//cellular homeostasis;GO:0032024//positive regulation of insulin secretion;GO:0050804//modulation of synaptic transmission;GO:0030098//lymphocyte differentiation;GO:0002260//lymphocyte homeostasis;GO:0014075//response to amine;GO:0006887//exocytosis;GO:0006796//phosphate-containing compound metabolic process;GO:0006351//transcription, DNA-templated;GO:0051705;GO:0007611//learning or memory;GO:0007409//axonogenesis;GO:0001911;GO:0006464//cellular protein modification process;GO:0042493//response to drug;GO:0042110//T cell activation;GO:0032024//positive regulation of insulin secretion;GO:0050804//modulation of synaptic transmission;GO:0030098//lymphocyte differentiation;GO:0002260//lymphocyte homeostasis;GO:0006887//exocytosis;GO:0006796//phosphate-containing compound metabolic process;GO:0006351//transcription, DNA-templated;GO:0051705;GO:0007611//learning or memory;GO:0007409//axonogenesis;GO:0010033//response to organic substance;GO:0001911;GO:0006464//cellular protein modification process;GO:0042493//response to drug;GO:0042110//T cell activation" gi|45592930|ref|NP_032940.1|/0/serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform 1 [Mus musculus] 16449 5493 2.74 2.36 -0.215389034 Down 0.246558727 Jag1 jagged 1 K06052|1|0.0|2673|mmu:16449|jagged GO:0044464;GO:0016021//integral component of membrane GO:0005102//receptor binding;GO:0046872//metal ion binding GO:0003158//endothelium development;GO:0007219//Notch signaling pathway;GO:0003151//outflow tract morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0048844//artery morphogenesis;GO:0060113//inner ear receptor cell differentiation;GO:0045165//cell fate commitment;GO:0008283//cell proliferation;GO:0003208//cardiac ventricle morphogenesis;GO:0044267//cellular protein metabolic process;GO:0003177;GO:1901652//response to peptide;GO:0009913//epidermal cell differentiation;GO:0035904//aorta development;GO:0045444//fat cell differentiation;GO:0055006//cardiac cell development;GO:0019827//stem cell population maintenance;GO:0002009//morphogenesis of an epithelium;GO:0030099//myeloid cell differentiation;GO:0042692//muscle cell differentiation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0072080//nephron tubule development;GO:0016477//cell migration gi|7305197|ref|NP_038850.1|/0/protein jagged-1 precursor [Mus musculus] 23832 4453 0.56 0.786666667 0.490325627 Up 0.246549325 Xcr1 chemokine (C motif) receptor 1 K04193|1|1e-175|620|mmu:23832|XC chemokine receptor 1 - - - - 100129 3777 7.026666667 6.383333333 -0.138530475 Down 0.246427094 Gpr153 G protein-coupled receptor 153 K08437|1|0.0|1176|mmu:100129|G protein-coupled receptor 153 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|33859807|ref|NP_848493.1|/0/probable G-protein coupled receptor 153 [Mus musculus] 17305 1834 6.123333333 6.763333333 0.143417239 Up 0.246427094 Mfng MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase K05948|1|0.0|653|mmu:17305|fringe [EC:2.4.1.222] GO:0031228//intrinsic component of Golgi membrane;GO:0044421 GO:0043169//cation binding;GO:0008375//acetylglucosaminyltransferase activity GO:0043393//regulation of protein binding;GO:0007219//Notch signaling pathway;GO:0007275//multicellular organism development "gi|6678872|ref|NP_032621.1|/0/beta-1,3-N-acetylglucosaminyltransferase manic fringe [Mus musculus]" 66586 1739.54 10.68333333 9.823333333 -0.121077296 Down 0.246380082 Crls1 cardiolipin synthase 1 K08744|1|1e-98|362|rno:366196|cardiolipin synthase (CMP-forming) [EC:2.7.8.41] - - - - 18007 7307 9.753333333 10.61 0.121457387 Up 0.246380082 Neo1 neogenin K06766|1|0.0|2655|mmu:18007|neogenin GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0050839//cell adhesion molecule binding;GO:0050839//cell adhesion molecule binding "GO:0022610;GO:0055080//cation homeostasis;GO:0000768//syncytium formation by plasma membrane fusion;GO:0006351//transcription, DNA-templated;GO:0022610;GO:0055080//cation homeostasis;GO:0000768//syncytium formation by plasma membrane fusion;GO:0006351//transcription, DNA-templated" "gi|148694013|gb|EDL25960.1|/0/neogenin, isoform CRA_a, partial [Mus musculus]" 68859 3422.5 9.553333333 10.41666667 0.12481758 Up 0.246380082 Smim1 small integral membrane protein 1 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|29124536|gb|AAH48911.1|/1.51949e-132/Lrrc47 protein, partial [Mus musculus]" 329910 5668 10.51333333 9.653333333 -0.123121058 Down 0.246380082 Acot11 acyl-CoA thioesterase 11 K12417|1|0.0|1206|mmu:329910|acyl-CoA thioesteraes 11 [EC:3.1.2.-] GO:0044424 GO:0016289//CoA hydrolase activity GO:0032787//monocarboxylic acid metabolic process;GO:0007165//signal transduction gi|22165404|ref|NP_079866.2|/0/acyl-coenzyme A thioesterase 11 [Mus musculus] 320139 3264 0.4 0.606666667 0.600904045 Up 0.24637068 Ptpn7 "protein tyrosine phosphatase, non-receptor type 7" K18019|1|0.0|702|mmu:320139|tyrosine-protein phosphatase non-receptor type 7 [EC:3.1.3.48] GO:0044459;GO:0043232;GO:0044444//cytoplasmic part GO:0004721//phosphoprotein phosphatase activity GO:0006470//protein dephosphorylation gi|564380626|ref|XP_006249882.1|/0/PREDICTED: tyrosine-protein phosphatase non-receptor type 7 isoform X2 [Rattus norvegicus] 218630 1876 0.213333333 0.396666667 0.894817763 Up 0.246342472 Ccno cyclin O K10861|1|1e-173|612|mmu:218630|uracil-DNA glycosylase 2 [EC:3.2.2.-] GO:0031981//nuclear lumen GO:0019900//kinase binding;GO:0019104//DNA N-glycosylase activity "GO:0006285//base-excision repair, AP site formation;GO:0051726//regulation of cell cycle;GO:0042221//response to chemical;GO:0007275//multicellular organism development" gi|124486694|ref|NP_001074531.1|/1.27332e-172/cyclin-O [Mus musculus] 56771 2040 4.41 4.936666667 0.162758579 Up 0.246295461 Med20 mediator complex subunit 20 K13528|1|1e-119|432|mmu:56771|mediator of RNA polymerase II transcription subunit 20 GO:0043234//protein complex;GO:0031981//nuclear lumen "GO:0005488//binding;GO:0034062//RNA polymerase activity;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" GO:0007519//skeletal muscle tissue development;GO:0006366//transcription from RNA polymerase II promoter gi|9910590|ref|NP_064432.1|/1.17312e-118/mediator of RNA polymerase II transcription subunit 20 [Mus musculus] 75076 1101 0.523333333 0.326666667 -0.679910905 Down 0.246276656 4930504C09Rik RIKEN cDNA 4930504C09 gene - - - - - 266614 1056 0.236666667 0.09 -1.394859617 Down 0.246248449 Ly6g5b "lymphocyte antigen 6 complex, locus G5B" K20005|1|4e-112|406|mmu:266614|lymphocyte antigen 6 complex locus protein G5 - - - gi|22507343|ref|NP_683741.1|/3.60848e-111/lymphocyte antigen 6 complex locus protein G5b precursor [Mus musculus] 20641 837 13.77 14.85 0.108934372 Up 0.246182632 Snrpd1 small nuclear ribonucleoprotein D1 K11087|1|2e-46|188|lcm:102365723|small nuclear ribonucleoprotein D1 GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding "GO:0000398//mRNA splicing, via spliceosome" "gi|148691046|gb|EDL22993.1|/2.08154e-54/mCG14669, isoform CRA_b, partial [Mus musculus]" 57751 1498 13.25333333 14.33666667 0.113354374 Up 0.246182632 Rnf25 ring finger protein 25 K10640|1|0.0|862|mmu:57751|E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0008134//transcription factor binding;GO:0019787//ubiquitin-like protein transferase activity GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032446//protein modification by small protein conjugation "gi|148667924|gb|EDL00341.1|/0/ring finger protein 25, isoform CRA_b, partial [Mus musculus]" 94043 1080 23.17666667 21.69 -0.095643036 Down 0.246163827 Tm2d1 TM2 domain containing 1 K03511|1|4e-10|68.2|tsp:Tsp_01714|DNA polymerase kappa [EC:2.7.7.7];K09488|2|1e-06|56.2|tsp:Tsp_13481|TNF receptor-associated protein 1 GO:0016021//integral component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0012501//programmed cell death gi|32171188|ref|NP_444387.1|/2.34677e-97/TM2 domain-containing protein 1 precursor [Mus musculus] 102633214 945 0.06 0.203333333 1.760812336 Up 0.246107413 Gm12925 predicted gene 12925 - - - - - 52864 5747 1.56 1.263333333 -0.304310681 Down 0.246088608 Slx4 SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) K10484|1|0.0|2900|mmu:52864|structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12) - - - - 68075 1427 0.866666667 1.13 0.38277365 Up 0.246050999 Lurap1 leucine rich adaptor protein 1 K10875|1|5e-14|81.6|hgl:101719853|DNA repair and recombination protein RAD54 and RAD54-like protein [EC:3.6.4.-] GO:0015629//actin cytoskeleton GO:0005488//binding GO:0048870//cell motility;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0001816//cytokine production;GO:0030036//actin cytoskeleton organization gi|242397481|ref|NP_080823.1|/5.45748e-106/leucine rich adaptor protein 1 [Mus musculus] 20452 5437 1.116666667 0.86 -0.37679003 Down 0.246050999 St8sia4 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4" "K06614|1|0.0|699|rno:116696|alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8D) [EC:2.4.99.-]" - GO:0008373//sialyltransferase activity;GO:0008373//sialyltransferase activity GO:0007155//cell adhesion;GO:0006487//protein N-linked glycosylation;GO:0007155//cell adhesion;GO:0006487//protein N-linked glycosylation "gi|122425617|ref|NP_446366.1|/0/CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase [Rattus norvegicus]" 215387 2702 1.12 0.863333333 -0.375509135 Down 0.246050999 Ncaph "non-SMC condensin I complex, subunit H" K06676|1|0.0|1354|mmu:215387|condensin complex subunit 2 GO:0043232;GO:0043231//intracellular membrane-bounded organelle - GO:0000070//mitotic sister chromatid segregation gi|295389521|ref|NP_659067.2|/0/condensin complex subunit 2 [Mus musculus] 272551 1061 0.84 1.096666667 0.38466385 Up 0.246050999 Gins2 GINS complex subunit 2 (Psf2 homolog) K10733|1|7e-102|372|mmu:272551|GINS complex subunit 2 GO:0031981//nuclear lumen GO:0005488//binding GO:0006261//DNA-dependent DNA replication;GO:0051320 gi|124249060|ref|NP_849187.1|/5.80203e-101/DNA replication complex GINS protein PSF2 [Mus musculus] 13168 575 0.453333333 0.266666667 -0.765534746 Down 0.245872353 Dbil5 diazepam binding inhibitor-like 5 "K08762|1|3e-23|110|cmy:102933180|diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein)" GO:0044424 GO:0043168//anion binding GO:0051234//establishment of localization;GO:0006732;GO:0048232//male gamete generation gi|10946592|ref|NP_067269.1|/3.41822e-43/diazepam-binding inhibitor-like 5 [Mus musculus] 207704 2932 4.016666667 3.553333333 -0.176825708 Down 0.245815939 Gtpbp10 GTP-binding protein 10 (putative) K03979|1|2e-38|164|bfo:BRAFLDRAFT_87647|GTPase [EC:3.6.5.-] GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0022613//ribonucleoprotein complex biogenesis gi|83320123|ref|NP_694756.1|/7.23462e-176/GTP-binding protein 10 [Mus musculus] 100763 5033 10.71666667 9.87 -0.118734247 Down 0.245797134 Ube3c ubiquitin protein ligase E3C K10589|1|0.0|2060|mmu:100763|ubiquitin-protein ligase E3 C [EC:2.3.2.26] - - - gi|28972031|dbj|BAC65469.1|/0/mKIAA0010 protein [Mus musculus] 433702 3167 9.83 10.68333333 0.120098534 Up 0.245797134 Ncbp1 nuclear cap binding protein subunit 1 K12882|1|0.0|1523|mmu:433702|nuclear cap-binding protein subunit 1 GO:0031981//nuclear lumen;GO:0034518//RNA cap binding complex;GO:0044444//cytoplasmic part GO:0003723//RNA binding "GO:0006413//translational initiation;GO:0016458//gene silencing;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0044764;GO:0031124//mRNA 3'-end processing;GO:0000398//mRNA splicing, via spliceosome;GO:0006405//RNA export from nucleus" gi|144922627|ref|NP_001028373.2|/0/nuclear cap-binding protein subunit 1 [Mus musculus] 53323 4882 12.89 13.95666667 0.114702154 Up 0.245787732 Ube2k ubiquitin-conjugating enzyme E2K K04649|1|2e-103|380|gja:107116469|ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23] GO:0044424;GO:0044424;GO:0044424 GO:0032550;GO:0044389//ubiquitin-like protein ligase binding;GO:0004842//ubiquitin-protein transferase activity;GO:0032550;GO:0044389//ubiquitin-like protein ligase binding;GO:0004842//ubiquitin-protein transferase activity;GO:0032550;GO:0044389//ubiquitin-like protein ligase binding;GO:0004842//ubiquitin-protein transferase activity GO:0034976//response to endoplasmic reticulum stress;GO:0061136//regulation of proteasomal protein catabolic process;GO:0000209//protein polyubiquitination;GO:0019941//modification-dependent protein catabolic process;GO:0034976//response to endoplasmic reticulum stress;GO:0061136//regulation of proteasomal protein catabolic process;GO:0000209//protein polyubiquitination;GO:0019941//modification-dependent protein catabolic process;GO:0034976//response to endoplasmic reticulum stress;GO:0061136//regulation of proteasomal protein catabolic process;GO:0000209//protein polyubiquitination;GO:0019941//modification-dependent protein catabolic process gi|511888671|ref|XP_004764077.1|/1.47515e-71/PREDICTED: ubiquitin-conjugating enzyme E2 K [Mustela putorius furo] 19164 3023 13.76333333 14.83666667 0.108337082 Up 0.245787732 Psen1 presenilin 1 K04505|1|0.0|754|mmu:19164|presenilin 1 [EC:3.4.23.-] - - - gi|6679493|ref|NP_032969.1|/0/presenilin-1 [Mus musculus] 52150 4089 1.943333333 2.29 0.236814216 Up 0.245712513 Kcnk6 "potassium inwardly-rectifying channel, subfamily K, member 6" K04917|1|1e-134|483|mmu:52150|potassium channel subfamily K member 6 GO:0031224//intrinsic component of membrane GO:0005261//cation channel activity GO:0034220//ion transmembrane transport gi|170295855|ref|NP_001028697.2|/1.29921e-133/potassium channel subfamily K member 6 [Mus musculus] 270192 4734 0.063333333 0.206666667 1.706268797 Up 0.24570311 Rab6b "RAB6B, member RAS oncogene family" K07894|1|4e-111|406|chx:102170824|Ras-related protein Rab-6B GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0012505//endomembrane system GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0048193//Golgi vesicle transport;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction gi|926684126|ref|XP_013821666.1|/3.0923e-110/PREDICTED: ras-related protein Rab-6B [Capra hircus] 17527 1704.47 46.50666667 49.45333333 0.088630228 Up 0.245684306 Mpv17 MpV17 mitochondrial inner membrane protein K13348|1|4e-91|338|mmu:17527|protein Mpv17 GO:0042579//microbody;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0042579//microbody;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0042579//microbody;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane - GO:0043583//ear development;GO:0065008//regulation of biological quality;GO:0030198//extracellular matrix organization;GO:0010823//negative regulation of mitochondrion organization;GO:0000302//response to reactive oxygen species;GO:0050954//sensory perception of mechanical stimulus;GO:0010727//negative regulation of hydrogen peroxide metabolic process;GO:0043583//ear development;GO:0065008//regulation of biological quality;GO:0030198//extracellular matrix organization;GO:0010823//negative regulation of mitochondrion organization;GO:0000302//response to reactive oxygen species;GO:0050954//sensory perception of mechanical stimulus;GO:0010727//negative regulation of hydrogen peroxide metabolic process;GO:0043583//ear development;GO:0065008//regulation of biological quality;GO:0030198//extracellular matrix organization;GO:0010823//negative regulation of mitochondrion organization;GO:0000302//response to reactive oxygen species;GO:0050954//sensory perception of mechanical stimulus;GO:0010727//negative regulation of hydrogen peroxide metabolic process gi|6678926|ref|NP_032648.1|/4.42278e-100/protein Mpv17 isoform 1 [Mus musculus] 228357 7140.68 1.556666667 1.876666667 0.269712372 Up 0.245646696 Lrp4 low density lipoprotein receptor-related protein 4 K20051|1|0.0|926|mmu:228357|low-density lipoprotein receptor-related protein 4 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding GO:0008544//epidermis development;GO:0042476//odontogenesis;GO:0072657//protein localization to membrane;GO:0001503//ossification;GO:0030326//embryonic limb morphogenesis;GO:0003002//regionalization;GO:0030178//negative regulation of Wnt signaling pathway;GO:0016192//vesicle-mediated transport;GO:0006468//protein phosphorylation;GO:0048869//cellular developmental process;GO:0007416//synapse assembly;GO:0008544//epidermis development;GO:0042476//odontogenesis;GO:0072657//protein localization to membrane;GO:0001503//ossification;GO:0030326//embryonic limb morphogenesis;GO:0003002//regionalization;GO:0030178//negative regulation of Wnt signaling pathway;GO:0016192//vesicle-mediated transport;GO:0006468//protein phosphorylation;GO:0048869//cellular developmental process;GO:0007416//synapse assembly gi|224994223|ref|NP_766256.3|/0/low-density lipoprotein receptor-related protein 4 isoform 1 precursor [Mus musculus] 75482 726 0.213333333 0.39 0.87036472 Up 0.245609086 Hspb9 "heat shock protein, alpha-crystallin-related, B9" K09547|1|5e-113|409|mmu:75482|heat shock protein beta-9 GO:0043231//intracellular membrane-bounded organelle - GO:0050896//response to stimulus gi|254675150|ref|NP_083583.1|/3.66665e-112/heat shock protein beta-9 [Mus musculus] 52690 2725 49.61666667 46.68333333 -0.087917238 Down 0.245609086 Setd3 SET domain containing 3 K19199|1|0.0|1152|mmu:52690|histone-lysine N-methyltransferase SETD3 [EC:2.1.1.43] GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0018024//histone-lysine N-methyltransferase activity;GO:0003712//transcription cofactor activity;GO:0001085//RNA polymerase II transcription factor binding GO:0006366//transcription from RNA polymerase II promoter;GO:0018022//peptidyl-lysine methylation;GO:0042692//muscle cell differentiation;GO:0034968//histone lysine methylation "gi|148686779|gb|EDL18726.1|/0/mCG18357, isoform CRA_d, partial [Mus musculus]" 23836 3722 0.3 0.143333333 -1.065588342 Down 0.245477453 Cdh20 cadherin 20 "K06807|1|0.0|1457|mmu:23836|cadherin 20, type 2" GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|7549750|ref|NP_035930.1|/0/cadherin-20 precursor [Mus musculus] 66609 1809 6.663333333 6.03 -0.144086064 Down 0.245449246 Cryzl1 "crystallin, zeta (quinone reductase)-like 1" "K00665|1|2e-08|63.2|hro:HELRODRAFT_99033|fatty acid synthase, animal type [EC:2.3.1.85];K00344|2|2e-08|63.2|ngi:103750546|NADPH2:quinone reductase [EC:1.6.5.5]" GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0044710;GO:0044710 gi|589941796|ref|XP_006983618.1|/0/PREDICTED: quinone oxidoreductase-like protein 1 [Peromyscus maniculatus bairdii] 66953 2361 0.273333333 0.463333333 0.761389068 Up 0.245392832 Cdca7 cell division cycle associated 7 - GO:0043231//intracellular membrane-bounded organelle - "GO:0044763;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation" gi|26324608|dbj|BAC26058.1|/7.33574e-176/unnamed protein product [Mus musculus] 223332 4298 0.336666667 0.536666667 0.672705395 Up 0.245392832 Ranbp3l RAN binding protein 3-like K15304|1|1e-172|610|aml:100480001|Ran-binding protein 3 - - GO:0006810//transport gi|37574124|ref|NP_932141.1|/0/ran-binding protein 3-like [Mus musculus] 100737 4143 3.076666667 3.506666667 0.188732152 Up 0.245383429 Dcun1d4 "DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)" K17824|1|1e-163|580|oas:101113593|DCN1-like protein 4/5 - - - gi|667297630|ref|XP_008580003.1|/1.08186e-140/PREDICTED: DCN1-like protein 4 isoform X2 [Galeopterus variegatus] 77264 6350.85 3.593333333 3.16 -0.185398214 Down 0.245383429 Zfp142 zinc finger protein 142 K09228|1|9e-73|279|bfo:BRAFLDRAFT_243940|KRAB domain-containing zinc finger protein - - - "gi|148667920|gb|EDL00337.1|/0/mCG133876, isoform CRA_d, partial [Mus musculus]" 109245 3072.91 46.03333333 43.16333333 -0.092872631 Down 0.245355222 Lrrc39 leucine rich repeat containing 39 K15446|1|1e-81|307|mmu:229780|tRNA:m4X modification enzyme [EC:2.1.1.225] - - - - 12841 2846 0.066666667 0.21 1.655351829 Up 0.245280003 Col9a3 "collagen, type IX, alpha 3" "K08131|1|6e-177|624|mmu:12841|collagen, type IX, alpha" - - - gi|112363119|ref|NP_034066.2|/5.34464e-176/collagen alpha-3(IX) chain precursor [Mus musculus] 18189 9004 0.21 0.066666667 -1.655351829 Down 0.245280003 Nrxn1 neurexin I K07377|1|0.0|2775|mmu:18189|neurexin "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0097060//synaptic membrane;GO:0030426//growth cone;GO:0031224//intrinsic component of membrane" GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0016247//channel regulator activity "GO:0009653//anatomical structure morphogenesis;GO:0001964//startle response;GO:0051094//positive regulation of developmental process;GO:0051705;GO:0072578//neurotransmitter-gated ion channel clustering;GO:0007611//learning or memory;GO:0051130//positive regulation of cellular component organization;GO:0007625//grooming behavior;GO:0045838//positive regulation of membrane potential;GO:0016337//single organismal cell-cell adhesion;GO:0035418//protein localization to synapse;GO:0044704//single-organism reproductive behavior;GO:0035249//synaptic transmission, glutamatergic;GO:0010469//regulation of receptor activity;GO:0097090//presynaptic membrane organization;GO:0001941//postsynaptic membrane organization;GO:0001505//regulation of neurotransmitter levels;GO:0051262//protein tetramerization;GO:0031345//negative regulation of cell projection organization" gi|28394197|dbj|BAC41433.2|/0/mKIAA0578 protein [Mus musculus] 433700 1596 0.306666667 0.146666667 -1.064130337 Down 0.245204784 Spag8 sperm associated antigen 8 - - - - - 76799 772 46.12666667 48.96666667 0.08619895 Up 0.245167174 Tmem234 transmembrane protein 234 K03246|1|3e-14|80.9|lve:103068681|translation initiation factor 3 subunit I GO:0031224//intrinsic component of membrane - - gi|22267454|ref|NP_084024.1|/5.87086e-66/transmembrane protein 234 precursor [Mus musculus] 192231 3401 9.46 10.29666667 0.122265282 Up 0.245120162 Hexim1 hexamethylene bis-acetamide inducible 1 K15189|1|4e-168|595|mmu:192231|protein HEXIM1/2 GO:0031981//nuclear lumen GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0003723//RNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0044767//single-organism developmental process gi|20270289|ref|NP_620092.1|/3.26423e-167/protein HEXIM1 [Mus musculus] 233824 2884 10.1 10.94 0.115257445 Up 0.245120162 Cog7 component of oligomeric golgi complex 7 K20294|1|0.0|1481|mmu:233824|conserved oligomeric Golgi complex subunit 7 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex - GO:0006464//cellular protein modification process;GO:0033365//protein localization to organelle;GO:0031647//regulation of protein stability;GO:0048193//Golgi vesicle transport;GO:0015031//protein transport gi|148685307|gb|EDL17254.1|/0/component of oligomeric golgi complex 7 [Mus musculus] 105734 4851 1.003333333 1.276666667 0.347580905 Up 0.245101358 Tigd5 tigger transposable element derived 5 K19326|1|8e-74|282|lcm:102349340|nesprin-1;K09229|2|8e-40|169|acs:100561333|KRAB and SCAN domains-containing zinc finger protein;K05164|3|3e-30|137|lcm:102357679|interleukin 17 receptor;K11496|4|1e-25|122|mdo:100031122|centromere protein B GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding - gi|111185889|ref|NP_848761.2|/0/tigger transposable element derived 5 [Mus musculus] 55963 3926 0.97 1.236666667 0.350400034 Up 0.245101358 Slc1a4 "solute carrier family 1 (glutamate/neutral amino acid transporter), member 4" "K05615|1|0.0|748|mmu:55963|solute carrier family 1 (glutamate/neutral amino acid transporter), member 4" GO:0043234//protein complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0016020//membrane GO:0005253//anion channel activity;GO:0000099;GO:0015291//secondary active transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity GO:0003333//amino acid transmembrane transport;GO:0000101//sulfur amino acid transport;GO:0015698//inorganic anion transport;GO:0015718//monocarboxylic acid transport;GO:0006812//cation transport;GO:0050877//neurological system process;GO:0015807//L-amino acid transport gi|254281331|ref|NP_061349.3|/0/neutral amino acid transporter A [Mus musculus] 18038 1470 7.52 8.226666667 0.129575327 Up 0.245073151 Nfkbil1 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1 K09256|1|0.0|713|mmu:18038|NF-kappa-B inhibitor-like protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding GO:0032496//response to lipopolysaccharide;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0002832;GO:0001818//negative regulation of cytokine production;GO:0002224//toll-like receptor signaling pathway;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity gi|6754844|ref|NP_035039.1|/0/NF-kappa-B inhibitor-like protein 1 [Mus musculus] 229473 4909 7.78 8.493333333 0.126560717 Up 0.245073151 D930015E06Rik RIKEN cDNA D930015E06 gene - GO:0031224//intrinsic component of membrane - - gi|114205395|ref|NP_766269.3|/0/transmembrane protein 131-like precursor [Mus musculus] 209416 3591 8.113333333 7.403333333 -0.132119775 Down 0.245073151 Gpkow G patch domain and KOW motifs K13101|1|0.0|917|mmu:209416|G patch domain and KOW motifs-containing protein GO:0031981//nuclear lumen - - gi|125991228|ref|NP_776108.2|/0/G patch domain and KOW motifs-containing protein [Mus musculus] 216987 3871 7.79 8.503333333 0.126405165 Up 0.245073151 Utp6 UTP6 small subunit processome component K14557|1|0.0|1202|mmu:216987|U3 small nucleolar RNA-associated protein 6 GO:0043231//intracellular membrane-bounded organelle - GO:0042254//ribosome biogenesis;GO:0010467//gene expression gi|21450209|ref|NP_659075.1|/0/U3 small nucleolar RNA-associated protein 6 homolog [Mus musculus] 56749 2318 8.133333333 7.423333333 -0.13177959 Down 0.245073151 Dhodh dihydroorotate dehydrogenase K00254|1|0.0|716|mmu:56749|dihydroorotate dehydrogenase [EC:1.3.5.2] GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane GO:0004152//dihydroorotate dehydrogenase activity;GO:0032553//ribonucleotide binding;GO:0048038//quinone binding GO:0044703;GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0007589//body fluid secretion;GO:0006915//apoptotic process;GO:0006222//UMP biosynthetic process;GO:0010821//regulation of mitochondrion organization;GO:0006950//response to stress;GO:0014074//response to purine-containing compound "gi|9910194|ref|NP_064430.1|/0/dihydroorotate dehydrogenase (quinone), mitochondrial precursor [Mus musculus]" 56421 4033 45.72 42.9 -0.091847756 Down 0.245054346 Pfkp "phosphofructokinase, platelet" K00850|1|0.0|1457|mmu:56421|6-phosphofructokinase 1 [EC:2.7.1.11] GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0032550;GO:0043168//anion binding;GO:0008443//phosphofructokinase activity;GO:0043169//cation binding;GO:0032550;GO:0043168//anion binding;GO:0008443//phosphofructokinase activity GO:0006007//glucose catabolic process;GO:0044710;GO:0051260//protein homooligomerization;GO:0016310//phosphorylation;GO:0006007//glucose catabolic process;GO:0051260//protein homooligomerization;GO:0016310//phosphorylation "gi|148700326|gb|EDL32273.1|/0/phosphofructokinase, platelet, isoform CRA_e, partial [Mus musculus]" 12506 1142 1.446666667 1.76 0.282842887 Up 0.244997931 Cd48 CD48 antigen K06479|1|4e-128|460|mmu:12506|CD48 antigen GO:0009986//cell surface;GO:0031225//anchored component of membrane;GO:0032991//macromolecular complex - GO:0002274;GO:0046649//lymphocyte activation;GO:0007154//cell communication gi|22094083|ref|NP_031675.1|/3.09706e-127/CD48 antigen precursor [Mus musculus] 269023 6112 2.38 2.023333333 -0.234227558 Down 0.244997931 Zfp608 zinc finger protein 608 K06783|1|4e-64|250|chx:102184188|cell adhesion molecule 4;K10847|2|5e-51|206|spu:582941|DNA-repair protein complementing XP-A cells - GO:0046872//metal ion binding - gi|113199757|ref|NP_786927.2|/0/zinc finger protein 608 [Mus musculus] 94281 2731 2.113333333 2.473333333 0.226936346 Up 0.244997931 Sfxn4 sideroflexin 4 - GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0015075//ion transmembrane transporter activity GO:0044763;GO:0055080//cation homeostasis;GO:0006811//ion transport gi|254826775|ref|NP_444428.3|/3.18785e-178/sideroflexin-4 [Mus musculus] 52552 3088 3.133333333 2.72 -0.204091605 Down 0.244988529 Parp8 "poly (ADP-ribose) polymerase family, member 8" K15258|1|0.0|1571|mmu:52552|poly [ADP-ribose] polymerase 6/8 [EC:2.4.2.30] - - - gi|124486598|ref|NP_001074478.1|/0/poly [ADP-ribose] polymerase 8 [Mus musculus] 67590 2754 3.8 4.276666667 0.170487346 Up 0.244932115 Tctn3 tectonic family member 3 K19382|1|0.0|1085|mmu:67590|tectonic-1/3 GO:0031224//intrinsic component of membrane - GO:0048858//cell projection morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0012501//programmed cell death gi|31541975|ref|NP_080536.2|/0/tectonic-3 precursor [Mus musculus] 68659 6627 4.35 3.866666667 -0.169925001 Down 0.244932115 Fam198b "family with sequence similarity 198, member B" - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|134032028|ref|NP_573450.2|/0/protein FAM198B [Mus musculus] 100500713 1684 0.79 1.04 0.39665897 Up 0.244903908 9530027J09Rik RIKEN cDNA 9530027J09 gene K14567|1|2e-53|213|mmu:72554|U3 small nucleolar RNA-associated protein 14 - - - - 107769 2114.13 4.383333333 4.903333333 0.161734447 Up 0.244903908 Tm6sf1 transmembrane 6 superfamily member 1 K06853|1|3e-95|352|apla:101804041|hyaluronan and proteoglycan link protein 4 GO:0031224//intrinsic component of membrane - - gi|164698485|ref|NP_663350.2|/0/transmembrane 6 superfamily member 1 isoform 1 [Mus musculus] 14102 1431.58 18.92666667 20.35 0.104608446 Up 0.244894505 Fas Fas (TNF receptor superfamily member 6) K04390|1|1e-179|631|mmu:14102|tumor necrosis factor receptor superfamily member 6 GO:0043231//intracellular membrane-bounded organelle;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0031264//death-inducing signaling complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0031264//death-inducing signaling complex;GO:0044444//cytoplasmic part GO:0005035//death receptor activity;GO:0019899//enzyme binding;GO:0005035//death receptor activity;GO:0019899//enzyme binding GO:0002449;GO:0070997//neuron death;GO:0043029//T cell homeostasis;GO:0009612//response to mechanical stimulus;GO:0070265//necrotic cell death;GO:0008283//cell proliferation;GO:0031102//neuron projection regeneration;GO:0010822//positive regulation of mitochondrion organization;GO:0019221//cytokine-mediated signaling pathway;GO:0002440;GO:0012502//induction of programmed cell death;GO:0048232//male gamete generation;GO:0031960//response to corticosteroid;GO:0042113//B cell activation;GO:0043170;GO:0002237//response to molecule of bacterial origin;GO:0002682//regulation of immune system process;GO:0032461//positive regulation of protein oligomerization;GO:0010226//response to lithium ion;GO:0043383//negative T cell selection;GO:0097191//extrinsic apoptotic signaling pathway;GO:0003008;GO:0002449;GO:0070997//neuron death;GO:0043029//T cell homeostasis;GO:0009612//response to mechanical stimulus;GO:0070265//necrotic cell death;GO:0008283//cell proliferation;GO:0031102//neuron projection regeneration;GO:0010822//positive regulation of mitochondrion organization;GO:0019221//cytokine-mediated signaling pathway;GO:0002440;GO:0012502//induction of programmed cell death;GO:0048232//male gamete generation;GO:0031960//response to corticosteroid;GO:0042113//B cell activation;GO:0043170;GO:0002237//response to molecule of bacterial origin;GO:0002682//regulation of immune system process;GO:0032461//positive regulation of protein oligomerization;GO:0010226//response to lithium ion;GO:0043383//negative T cell selection;GO:0097191//extrinsic apoptotic signaling pathway;GO:0003008 gi|226443053|ref|NP_001140180.1|/1.02317e-30/tumor necrosis factor receptor superfamily member 6 isoform 2 precursor [Mus musculus] 56273 1942 18.81666667 20.23666667 0.104960592 Up 0.244894505 Pex14 peroxisomal biogenesis factor 14 K13343|1|3e-156|554|mmu:56273|peroxin-14 GO:0032991//macromolecular complex;GO:0031224//intrinsic component of membrane;GO:0044439 GO:0003712//transcription cofactor activity;GO:0015631//tubulin binding "GO:0006351//transcription, DNA-templated;GO:0000226//microtubule cytoskeleton organization;GO:0043393//regulation of protein binding;GO:0016558//protein import into peroxisome matrix;GO:0032463//negative regulation of protein homooligomerization;GO:0044092//negative regulation of molecular function;GO:0072384//organelle transport along microtubule" gi|9790153|ref|NP_062755.1|/2.50685e-155/peroxisomal membrane protein PEX14 [Mus musculus] 666532 2812 0.926666667 0.686666667 -0.432440546 Down 0.244725262 Gm13139 zinc finger protein 991 K09228|1|0.0|1241|mmu:666532|KRAB domain-containing zinc finger protein - - - gi|145046227|ref|NP_001077387.1|/0/uncharacterized protein LOC666532 [Mus musculus] 14317 2710 0.216666667 0.393333333 0.860275236 Up 0.244687653 Ftcd formiminotransferase cyclodeaminase K13990|1|0.0|1001|mmu:14317|glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4] GO:0043231//intracellular membrane-bounded organelle;GO:0005813//centrosome GO:0019842//vitamin binding;GO:0030407//formimidoyltransferase activity;GO:0016841//ammonia-lyase activity;GO:0032403//protein complex binding GO:0006996//organelle organization;GO:0006730//one-carbon metabolic process;GO:0006536//glutamate metabolic process;GO:0006547//histidine metabolic process gi|18252784|ref|NP_543121.1|/0/formimidoyltransferase-cyclodeaminase [Mus musculus] 13841 6507.51 0.216666667 0.393333333 0.860275236 Up 0.244687653 Epha7 Eph receptor A7 K05108|1|0.0|1201|mmu:13841|EphA7 [EC:2.7.10.1] GO:0043005//neuron projection;GO:0097060//synaptic membrane;GO:0044297//cell body;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0097060//synaptic membrane;GO:0044297//cell body;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0097060//synaptic membrane;GO:0044297//cell body;GO:0016021//integral component of membrane GO:0005102//receptor binding;GO:0032550;GO:0005003//ephrin receptor activity;GO:0005102//receptor binding;GO:0032550;GO:0005003//ephrin receptor activity;GO:0005102//receptor binding;GO:0032550;GO:0005003//ephrin receptor activity GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0016337//single organismal cell-cell adhesion;GO:0043408//regulation of MAPK cascade;GO:0001763//morphogenesis of a branching structure;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0016337//single organismal cell-cell adhesion;GO:0043408//regulation of MAPK cascade;GO:0001763//morphogenesis of a branching structure;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0016337//single organismal cell-cell adhesion;GO:0043408//regulation of MAPK cascade;GO:0001763//morphogenesis of a branching structure;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:0043065//positive regulation of apoptotic process gi|171541811|ref|NP_034271.3|/0/ephrin type-A receptor 7 isoform 1 precursor [Mus musculus] 76238 1281 41.32666667 44.05333333 0.092178183 Up 0.244631238 Grhpr glyoxylate reductase/hydroxypyruvate reductase K00049|1|1e-178|628|mmu:76238|glyoxylate/hydroxypyruvate reductase [EC:1.1.1.79 1.1.1.81] - - - - 74633 1520 5.71 5.146666667 -0.149852399 Down 0.244546617 4930429F24Rik RIKEN cDNA 4930429F24 gene - - - - - 12660 2627 5.11 5.673333333 0.15087334 Up 0.244546617 Chka choline kinase alpha K14156|1|0.0|798|mmu:12660|choline/ethanolamine kinase [EC:2.7.1.32 2.7.1.82] GO:0044424;GO:0044424;GO:0044424 GO:0043169//cation binding;GO:0032550;GO:0042802//identical protein binding;GO:0052689//carboxylic ester hydrolase activity;GO:0016301//kinase activity;GO:0043169//cation binding;GO:0032550;GO:0042802//identical protein binding;GO:0052689//carboxylic ester hydrolase activity;GO:0016301//kinase activity;GO:0043169//cation binding;GO:0032550;GO:0042802//identical protein binding;GO:0052689//carboxylic ester hydrolase activity;GO:0016301//kinase activity GO:0006656//phosphatidylcholine biosynthetic process;GO:0046337//phosphatidylethanolamine metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0046337//phosphatidylethanolamine metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0046337//phosphatidylethanolamine metabolic process gi|70908364|ref|NP_038518.2|/0/choline kinase alpha isoform 1 [Mus musculus] 257635 1223 5.213333333 5.773333333 0.147198417 Up 0.244546617 Sdsl serine dehydratase-like K17989|1|4e-163|576|mmu:257635|L-serine/L-threonine ammonia-lyase [EC:4.3.1.17 4.3.1.19] GO:0043231//intracellular membrane-bounded organelle GO:0016841//ammonia-lyase activity - gi|755513685|ref|XP_011246504.1|/4.5985e-168/PREDICTED: serine dehydratase-like isoform X2 [Mus musculus] 66964 2796 5.943333333 6.56 0.142423518 Up 0.24451841 Golt1b golgi transport 1B K14396|1|1e-32|144|tsp:Tsp_06460|polyadenylate-binding protein 2 - - - - 382045 2820 0.036666667 0.166666667 2.184424571 Up 0.2444808 Adgrg5 adhesion G protein-coupled receptor G5 K08459|1|0.0|977|mmu:382045|G protein-coupled receptor 114 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway gi|568957117|ref|XP_006531217.1|/0/PREDICTED: probable G-protein coupled receptor 114 isoform X3 [Mus musculus] 75410 8484 8.08 7.376666667 -0.131386248 Down 0.244433788 Kmt2b lysine (K)-specific methyltransferase 2B K14959|1|0.0|3601|mmu:75410|histone-lysine N-methyltransferase MLL4 [EC:2.1.1.43] - - - gi|594542481|ref|NP_001277502.1|/0/histone-lysine N-methyltransferase 2B isoform 1 [Mus musculus] 241528 2900 0.036666667 0.163333333 2.155278225 Up 0.244377374 Lrrc55 leucine rich repeat containing 55 K06838|1|6e-23|112|mze:101467001|slit 1 GO:0031224//intrinsic component of membrane GO:0015075//ion transmembrane transporter activity GO:0044765//single-organism transport gi|85701836|ref|NP_001028518.1|/2.62118e-178/leucine-rich repeat-containing protein 55 precursor [Mus musculus] 21400 1163 2.9 2.51 -0.208365536 Down 0.244367972 Tcea2 "transcription elongation factor A (SII), 2" K03145|1|7e-159|562|mmu:21400|transcription elongation factor S-II GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen "GO:0046914//transition metal ion binding;GO:0008135//translation factor activity, RNA binding" "GO:0006412//translation;GO:0006354//DNA-templated transcription, elongation;GO:0006366//transcription from RNA polymerase II promoter" gi|6678235|ref|NP_033352.1|/5.95851e-158/transcription elongation factor A protein 2 [Mus musculus] 74197 3058 2.42 2.806666667 0.213850685 Up 0.244367972 Gtf2e1 "general transcription factor II E, polypeptide 1 (alpha subunit)" K03136|1|0.0|704|mmu:74197|transcription initiation factor TFIIE subunit alpha GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003677//DNA binding GO:0006366//transcription from RNA polymerase II promoter gi|21312660|ref|NP_083088.1|/0/general transcription factor IIE subunit 1 [Mus musculus] 13601 1898.96 42.13 39.44666667 -0.094944522 Down 0.244358569 Ecm1 extracellular matrix protein 1 - GO:0044421;GO:0031012//extracellular matrix;GO:0044421;GO:0031012//extracellular matrix GO:0060089;GO:0005126//cytokine receptor binding;GO:0019899//enzyme binding;GO:0060089;GO:0005126//cytokine receptor binding;GO:0019899//enzyme binding GO:0001525//angiogenesis;GO:0009888//tissue development;GO:0006366//transcription from RNA polymerase II promoter;GO:0001935//endothelial cell proliferation;GO:0042092//type 2 immune response;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0030279//negative regulation of ossification;GO:0051346//negative regulation of hydrolase activity;GO:0072678//T cell migration;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006952//defense response;GO:0001525//angiogenesis;GO:0009888//tissue development;GO:0006366//transcription from RNA polymerase II promoter;GO:0001935//endothelial cell proliferation;GO:0042092//type 2 immune response;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0030279//negative regulation of ossification;GO:0051346//negative regulation of hydrolase activity;GO:0072678//T cell migration;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006952//defense response gi|170295832|ref|NP_031925.2|/0/extracellular matrix protein 1 isoform 1 precursor [Mus musculus] 20927 4952 13.11666667 14.14333333 0.108721043 Up 0.244358569 Abcc8 "ATP-binding cassette, sub-family C (CFTR/MRP), member 8" K05032|1|0.0|2826|mmu:20927|ATP-binding cassette subfamily C (CFTR/MRP) member 8 GO:0008021//synaptic vesicle;GO:0005887//integral component of plasma membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0000149//SNARE binding;GO:0005261//cation channel activity;GO:0015405;GO:0004888//transmembrane signaling receptor activity GO:0050796//regulation of insulin secretion;GO:0043434//response to peptide hormone;GO:0010038//response to metal ion;GO:0009628//response to abiotic stimulus;GO:0034220//ion transmembrane transport;GO:0006813//potassium ion transport;GO:0002237//response to molecule of bacterial origin gi|62241017|ref|NP_035640.2|/0/ATP-binding cassette sub-family C member 8 [Mus musculus] 74045 1790 2.286666667 2.656666667 0.216371148 Up 0.244226936 Slc36a1os "solute carrier family 36 (proton/amino acid symporter), member 1, opposite strand" - - - - - 19267 5147.67 1.176666667 1.463333333 0.314552756 Up 0.244198729 Ptpre "protein tyrosine phosphatase, receptor type, E" K18033|1|0.0|1307|cge:100756593|receptor-type tyrosine-protein phosphatase epsilon [EC:3.1.3.48] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton GO:0042802//identical protein binding;GO:0004721//phosphoprotein phosphatase activity GO:0008286//insulin receptor signaling pathway;GO:0002694;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process gi|940373612|ref|NP_001303609.1|/0/receptor-type tyrosine-protein phosphatase epsilon isoform c precursor [Mus musculus] 228005 6297 3.746666667 3.3 -0.183141605 Down 0.244104705 Ppig peptidyl-prolyl isomerase G (cyclophilin G) K09566|1|2e-165|587|mmu:228005|peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8] GO:0034399//nuclear periphery GO:0016859//cis-trans isomerase activity - gi|124487333|ref|NP_001074555.1|/1.32877e-164/peptidyl-prolyl cis-trans isomerase G [Mus musculus] 17064 6638 19.72333333 18.34333333 -0.104647566 Down 0.244020083 Cd93 CD93 antigen K06702|1|0.0|1217|mmu:17064|CDW93 antigen GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding;GO:0001846//opsonin binding GO:0007155//cell adhesion gi|6754578|ref|NP_034870.1|/0/complement component C1q receptor precursor [Mus musculus] 16438 9877 1.923333333 1.606666667 -0.259538172 Down 0.244001279 Itpr1 "inositol 1,4,5-trisphosphate receptor 1" "K04958|1|0.0|5219|mmu:16438|inositol 1,4,5-triphosphate receptor type 1" GO:0031981//nuclear lumen;GO:0044327//dendritic spine head;GO:0044297//cell body;GO:0008287//protein serine/threonine phosphatase complex;GO:0031224//intrinsic component of membrane;GO:0030667//secretory granule membrane;GO:0019866//organelle inner membrane;GO:0005783//endoplasmic reticulum GO:0005217//intracellular ligand-gated ion channel activity;GO:0005543//phospholipid binding;GO:0019902//phosphatase binding GO:0050881//musculoskeletal movement;GO:0007275//multicellular organism development;GO:0060548//negative regulation of cell death;GO:0006816//calcium ion transport;GO:0051283//negative regulation of sequestering of calcium ion;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0034976//response to endoplasmic reticulum stress;GO:0001666//response to hypoxia;GO:0019932//second-messenger-mediated signaling "gi|672050620|ref|XP_008761391.1|/0/PREDICTED: inositol 1,4,5-trisphosphate receptor type 1 isoform X3 [Rattus norvegicus]" 117600 7718 1.066666667 0.816666667 -0.385290156 Down 0.243916657 Srgap1 SLIT-ROBO Rho GTPase activating protein 1 K07526|1|0.0|1991|mmu:117600|SLIT-ROBO Rho GTPase activating protein GO:0044444//cytoplasmic part;GO:0044464 GO:0017016//Ras GTPase binding;GO:0017016//Ras GTPase binding GO:0048870//cell motility;GO:0006935//chemotaxis;GO:0048870//cell motility;GO:0007265//Ras protein signal transduction gi|334724478|ref|NP_001229340.1|/0/SLIT-ROBO Rho GTPase-activating protein 1 isoform 2 [Mus musculus] 319149 504 0.366666667 0.57 0.636492801 Up 0.243794426 Hist1h3d "histone cluster 1, H3d" K11253|1|2e-66|253|shr:100927605|histone H3 - - - gi|880967054|ref|XP_012981125.1|/4.04727e-69/PREDICTED: LOW QUALITY PROTEIN: histone H3-like centromeric protein CSE4 [Mesocricetus auratus] 19013 7246.17 19.78666667 18.43 -0.10247252 Down 0.243662793 Ppara peroxisome proliferator activated receptor alpha K07294|1|0.0|870|mmu:19013|peroxisome proliferator-activated receptor alpha GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0044390//ubiquitin-like protein conjugating enzyme binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0038023//signaling receptor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0044390//ubiquitin-like protein conjugating enzyme binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0038023//signaling receptor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding" GO:0006869//lipid transport;GO:0043434//response to peptide hormone;GO:0030534//adult behavior;GO:0043392//negative regulation of DNA binding;GO:0034505//tooth mineralization;GO:0006096//glycolytic process;GO:0008217//regulation of blood pressure;GO:0010742//macrophage derived foam cell differentiation;GO:0032096//negative regulation of response to food;GO:0019538//protein metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010878//cholesterol storage;GO:0043393//regulation of protein binding;GO:0060548//negative regulation of cell death;GO:0009755//hormone-mediated signaling pathway;GO:0010558;GO:0006635//fatty acid beta-oxidation;GO:0009611//response to wounding;GO:0010888//negative regulation of lipid storage;GO:0006869//lipid transport;GO:0043434//response to peptide hormone;GO:0030534//adult behavior;GO:0043392//negative regulation of DNA binding;GO:0034505//tooth mineralization;GO:0006096//glycolytic process;GO:0008217//regulation of blood pressure;GO:0010742//macrophage derived foam cell differentiation;GO:0032096//negative regulation of response to food;GO:0019538//protein metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010878//cholesterol storage;GO:0043393//regulation of protein binding;GO:0060548//negative regulation of cell death;GO:0009755//hormone-mediated signaling pathway;GO:0010558;GO:0006635//fatty acid beta-oxidation;GO:0009611//response to wounding;GO:0010888//negative regulation of lipid storage "gi|148672481|gb|EDL04428.1|/0/peroxisome proliferator activated receptor alpha, isoform CRA_b, partial [Mus musculus]" 104709 3238 4.953333333 4.446666667 -0.155675449 Down 0.243643988 Pik3r6 "phosphoinositide-3-kinase, regulatory subunit 6" "K02649|1|7e-22|109|phd:102329584|phosphoinositide-3-kinase, regulatory subunit" GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005942//phosphatidylinositol 3-kinase complex GO:0035014//phosphatidylinositol 3-kinase regulator activity;GO:0052813//phosphatidylinositol bisphosphate kinase activity;GO:0005488//binding;GO:0035014//phosphatidylinositol 3-kinase regulator activity;GO:0052813//phosphatidylinositol bisphosphate kinase activity;GO:0005488//binding;GO:0035014//phosphatidylinositol 3-kinase regulator activity;GO:0052813//phosphatidylinositol bisphosphate kinase activity GO:0001525//angiogenesis;GO:0043550//regulation of lipid kinase activity;GO:0007166//cell surface receptor signaling pathway;GO:0007599//hemostasis;GO:0046474//glycerophospholipid biosynthetic process;GO:0043405//regulation of MAP kinase activity;GO:0001775//cell activation;GO:0001525//angiogenesis;GO:0043550//regulation of lipid kinase activity;GO:0007166//cell surface receptor signaling pathway;GO:0007599//hemostasis;GO:0046474//glycerophospholipid biosynthetic process;GO:0043405//regulation of MAP kinase activity;GO:0001775//cell activation;GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0043550//regulation of lipid kinase activity;GO:0043405//regulation of MAP kinase activity gi|52138727|ref|NP_001004435.1|/0/phosphoinositide 3-kinase regulatory subunit 6 isoform 2 [Mus musculus] 17035 1092 4.363333333 4.876666667 0.160464672 Up 0.243643988 Lxn latexin - GO:0044424 GO:0005539//glycosaminoglycan binding;GO:0004866//endopeptidase inhibitor activity GO:0010466//negative regulation of peptidase activity;GO:0006952//defense response;GO:0019233//sensory perception of pain "gi|61680221|pdb|1WNH|A/1.53499e-128/Chain A, Crystal Structure Of Mouse Latexin (Tissue Carboxypeptidase Inhibitor)" 21771 2255 12.65666667 13.67 0.111115745 Up 0.243568769 Cirh1a "cirrhosis, autosomal recessive 1A (human)" K14548|1|0.0|1394|mmu:21771|U3 small nucleolar RNA-associated protein 4 GO:0031981//nuclear lumen - "GO:0006351//transcription, DNA-templated" gi|50511221|dbj|BAD32596.1|/0/mKIAA1988 protein [Mus musculus] 259104 5137 6.09 6.703333333 0.138436448 Up 0.243559367 Olfr613 olfactory receptor 613 K04257|1|7e-171|604|mmu:259104|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007154//cell communication gi|238637320|ref|NP_667311.3|/6.46463e-170/olfactory receptor 614 [Mus musculus] 76183 2675.29 1.406666667 1.123333333 -0.324494408 Down 0.243549964 Celf6 "CUGBP, Elav-like family member 6" K13207|1|0.0|705|rno:300758|CUG-BP- and ETR3-like factor GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0000380//alternative mRNA splicing, via spliceosome" "gi|148694025|gb|EDL25972.1|/0/bruno-like 6, RNA binding protein (Drosophila), isoform CRA_a, partial [Mus musculus]" 20698 1822.61 1.123333333 1.403333333 0.321071642 Up 0.243549964 Sphk1 sphingosine kinase 1 K04718|1|0.0|680|mmu:20698|sphingosine kinase [EC:2.7.1.91] GO:0043005//neuron projection;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane;GO:0043005//neuron projection;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane;GO:0043005//neuron projection;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane;GO:0043005//neuron projection;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane;GO:0043005//neuron projection;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane GO:0001727//lipid kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0003676//nucleic acid binding;GO:0019903//protein phosphatase binding;GO:0001727//lipid kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0003676//nucleic acid binding;GO:0019903//protein phosphatase binding;GO:0001727//lipid kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0003676//nucleic acid binding;GO:0019903//protein phosphatase binding;GO:0001727//lipid kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0003676//nucleic acid binding;GO:0019903//protein phosphatase binding;GO:0001727//lipid kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0003676//nucleic acid binding;GO:0019903//protein phosphatase binding GO:0006066//alcohol metabolic process;GO:0030149//sphingolipid catabolic process;GO:0034614//cellular response to reactive oxygen species;GO:0001932//regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0032611//interleukin-1 beta production;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0019932//second-messenger-mediated signaling;GO:0006458//'de novo' protein folding;GO:0010243//response to organonitrogen compound;GO:0006952//defense response;GO:0016567//protein ubiquitination;GO:0016049//cell growth;GO:0016477//cell migration;GO:0010975//regulation of neuron projection development;GO:0001516//prostaglandin biosynthetic process;GO:0070848//response to growth factor;GO:0000278//mitotic cell cycle;GO:0046683//response to organophosphorus;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0044703;GO:0010038//response to metal ion;GO:0048545//response to steroid hormone;GO:0007417//central nervous system development;GO:0006939//smooth muscle contraction;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0007269//neurotransmitter secretion;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0006066//alcohol metabolic process;GO:0030149//sphingolipid catabolic process;GO:0034614//cellular response to reactive oxygen species;GO:0001932//regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0032611//interleukin-1 beta production;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0019932//second-messenger-mediated signaling;GO:0006458//'de novo' protein folding;GO:0010243//response to organonitrogen compound;GO:0006952//defense response;GO:0016567//protein ubiquitination;GO:0016049//cell growth;GO:0016477//cell migration;GO:0010975//regulation of neuron projection development;GO:0001516//prostaglandin biosynthetic process;GO:0070848//response to growth factor;GO:0000278//mitotic cell cycle;GO:0046683//response to organophosphorus;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0044703;GO:0010038//response to metal ion;GO:0048545//response to steroid hormone;GO:0007417//central nervous system development;GO:0006939//smooth muscle contraction;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0007269//neurotransmitter secretion;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0006066//alcohol metabolic process;GO:0030149//sphingolipid catabolic process;GO:0034614//cellular response to reactive oxygen species;GO:0001932//regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0032611//interleukin-1 beta production;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0019932//second-messenger-mediated signaling;GO:0006458//'de novo' protein folding;GO:0010243//response to organonitrogen compound;GO:0006952//defense response;GO:0016567//protein ubiquitination;GO:0016049//cell growth;GO:0016477//cell migration;GO:0010975//regulation of neuron projection development;GO:0001516//prostaglandin biosynthetic process;GO:0070848//response to growth factor;GO:0000278//mitotic cell cycle;GO:0046683//response to organophosphorus;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0044703;GO:0010038//response to metal ion;GO:0048545//response to steroid hormone;GO:0007417//central nervous system development;GO:0006939//smooth muscle contraction;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0007269//neurotransmitter secretion;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0006066//alcohol metabolic process;GO:0030149//sphingolipid catabolic process;GO:0034614//cellular response to reactive oxygen species;GO:0001932//regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0032611//interleukin-1 beta production;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0019932//second-messenger-mediated signaling;GO:0006458//'de novo' protein folding;GO:0010243//response to organonitrogen compound;GO:0006952//defense response;GO:0016567//protein ubiquitination;GO:0016049//cell growth;GO:0016477//cell migration;GO:0010975//regulation of neuron projection development;GO:0001516//prostaglandin biosynthetic process;GO:0070848//response to growth factor;GO:0000278//mitotic cell cycle;GO:0046683//response to organophosphorus;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0044703;GO:0010038//response to metal ion;GO:0048545//response to steroid hormone;GO:0007417//central nervous system development;GO:0006939//smooth muscle contraction;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0007269//neurotransmitter secretion;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0006066//alcohol metabolic process;GO:0034614//cellular response to reactive oxygen species;GO:0001932//regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0032611//interleukin-1 beta production;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0019932//second-messenger-mediated signaling;GO:0010243//response to organonitrogen compound;GO:0006952//defense response;GO:0016567//protein ubiquitination;GO:0016049//cell growth;GO:0016477//cell migration;GO:0010975//regulation of neuron projection development;GO:0001516//prostaglandin biosynthetic process;GO:0070848//response to growth factor;GO:0000278//mitotic cell cycle;GO:0046683//response to organophosphorus;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0044703;GO:0010038//response to metal ion;GO:0048545//response to steroid hormone;GO:0007417//central nervous system development;GO:0006939//smooth muscle contraction;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0007269//neurotransmitter secretion;GO:0042345//regulation of NF-kappaB import into nucleus "gi|148702636|gb|EDL34583.1|/0/sphingosine kinase 1, isoform CRA_c, partial [Mus musculus]" 14672 3262 37.93666667 40.47333333 0.093378752 Up 0.24353116 Gna11 "guanine nucleotide binding protein, alpha 11" K04635|1|0.0|714|cge:100689065|guanine nucleotide-binding protein subunit alpha-11 - - - gi|6754004|ref|NP_034431.1|/0/guanine nucleotide-binding protein subunit alpha-11 [Mus musculus] 18030 2019 9.883333333 9.076666667 -0.122835122 Down 0.243521757 Nfil3 "nuclear factor, interleukin 3, regulated" "K09059|1|0.0|859|mmu:18030|nuclear factor, interleukin 3 regulated" - - - - 16563 4047.44 4.876666667 5.426666667 0.15417093 Up 0.243380721 Kif2a kinesin family member 2A K10393|1|0.0|1283|mmu:16563|kinesin family member 2/24 GO:0005815//microtubule organizing center;GO:0000323//lytic vacuole;GO:0005819//spindle;GO:0005815//microtubule organizing center;GO:0000323//lytic vacuole;GO:0005819//spindle GO:0032550;GO:0003774//motor activity;GO:0032550;GO:0003774//motor activity GO:0048869//cellular developmental process;GO:0048731//system development;GO:0000087//mitotic M phase;GO:0006928//movement of cell or subcellular component;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0000087//mitotic M phase;GO:0006928//movement of cell or subcellular component gi|568984232|ref|XP_006517598.1|/0/PREDICTED: kinesin-like protein KIF2A isoform X2 [Mus musculus] 75805 3780 4.25 3.776666667 -0.170349386 Down 0.243324307 Nln neurolysin (metallopeptidase M3 family) K01393|1|0.0|1415|mmu:75805|neurolysin [EC:3.4.24.16] - - - - 64011 1293 4.163333333 3.693333333 -0.172815596 Down 0.243324307 Nrgn neurogranin - GO:0042995//cell projection GO:0005515//protein binding GO:0035556//intracellular signal transduction gi|148693489|gb|EDL25436.1|/3.34053e-59/neurogranin [Mus musculus] 210544 3318 1.173333333 0.913333333 -0.361399536 Down 0.243305502 Tbc1d31 "TBC1 domain family, member 31" K16794|1|1e-14|85.5|cbr:CBG21225|platelet-activating factor acetylhydrolase IB subunit alpha GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center - - gi|264681545|ref|NP_001161151.1|/0/TBC1 domain family member 31 isoform 2 [Mus musculus] 110380 4995.88 1.173333333 0.916666667 -0.35614381 Down 0.243305502 Shroom2 shroom family member 2 K18625|1|0.0|2835|mmu:110380|protein Shroom - - - - 234356 3943 1.203333333 0.94 -0.356303674 Down 0.243305502 Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 K00746|1|0.0|1030|mmu:234356|chondroitin sulfate N-acetylgalactosaminyltransferase 1/2 [EC:2.4.1.174 2.4.1.175] GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane GO:0043169//cation binding;GO:0008376//acetylgalactosaminyltransferase activity;GO:0043169//cation binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0043062//extracellular structure organization;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0006040//amino sugar metabolic process;GO:0001501//skeletal system development;GO:0036075;GO:0009225//nucleotide-sugar metabolic process;GO:0033692//cellular polysaccharide biosynthetic process;GO:0043062//extracellular structure organization;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0006040//amino sugar metabolic process;GO:0001501//skeletal system development;GO:0036075;GO:0009225//nucleotide-sugar metabolic process;GO:0033692//cellular polysaccharide biosynthetic process gi|225543170|ref|NP_766341.4|/0/chondroitin sulfate N-acetylgalactosaminyltransferase 1 [Mus musculus] 14269 4587.13 18.16666667 19.50666667 0.10267354 Up 0.243267893 Fnbp1 formin binding protein 1 K20121|1|0.0|991|mmu:14269|formin-binding protein 1 GO:0000323//lytic vacuole;GO:0012505//endomembrane system;GO:0031982//vesicle;GO:0043232;GO:0016020//membrane;GO:0000323//lytic vacuole;GO:0012505//endomembrane system;GO:0043232;GO:0016020//membrane;GO:0000323//lytic vacuole;GO:0012505//endomembrane system;GO:0043232;GO:0016020//membrane GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0048731//system development;GO:0016192//vesicle-mediated transport;GO:0048731//system development;GO:0016192//vesicle-mediated transport;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0016192//vesicle-mediated transport;GO:0048869//cellular developmental process gi|74152512|dbj|BAE33974.1|/0/unnamed protein product [Mus musculus] 67877 1168.51 39.23666667 41.70666667 0.088075529 Up 0.243108052 Naa20 "N(alpha)-acetyltransferase 20, NatB catalytic subunit" K17972|1|5e-105|383|rno:362228|N-terminal acetyltransferase B complex catalytic subunit [EC:2.3.1.88] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0034212//peptide N-acetyltransferase activity;GO:0034212//peptide N-acetyltransferase activity - gi|13385922|ref|NP_080701.1|/3.98058e-104/N-alpha-acetyltransferase 20 isoform 2 [Mus musculus] 117589 4893 2.073333333 1.743333333 -0.250103634 Down 0.243079845 Asb7 ankyrin repeat and SOCS box-containing 7 K10329|1|1e-165|471|dre:405798|ankyrin repeat and SOCS box protein 7 - - GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation gi|159106931|ref|NP_536691.2|/0/ankyrin repeat and SOCS box protein 7 [Mus musculus] 329584 2986 1.753333333 2.08 0.24648323 Up 0.243079845 Slc2a4rg-ps "Slc2a4 regulator, pseudogene" - - - - - 11932 2959 18.39666667 19.73 0.100946571 Up 0.243051638 Atp1b2 "ATPase, Na+/K+ transporting, beta 2 polypeptide" K01540|1|6e-173|610|mmu:11932|sodium/potassium-transporting ATPase subunit beta GO:0005887//integral component of plasma membrane;GO:0044424 - GO:0022610;GO:0030001//metal ion transport gi|7242138|ref|NP_038201.1|/4.90565e-172/sodium/potassium-transporting ATPase subunit beta-2 [Mus musculus] 104303 842 36.54 39 0.09399749 Up 0.243032833 Arl1 ADP-ribosylation factor-like 1 K07942|1|2e-90|334|hgl:101712001|ADP-ribosylation factor-like protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0043169//cation binding;GO:0030234//enzyme regulator activity GO:0019748//secondary metabolic process;GO:0006996//organelle organization;GO:0016192//vesicle-mediated transport;GO:0009154//purine ribonucleotide catabolic process;GO:0033365//protein localization to organelle;GO:0010518//positive regulation of phospholipase activity;GO:0035556//intracellular signal transduction gi|795427757|ref|XP_011760078.1|/8.14923e-91/PREDICTED: ADP-ribosylation factor-like protein 1 [Macaca nemestrina] 17119 4662 2.71 3.113333333 0.200167198 Up 0.243014028 Mxd1 MAX dimerization protein 1 K09114|1|8e-89|332|mmu:17119|MAX dimerization protein - GO:0005515//protein binding "GO:0006351//transcription, DNA-templated" gi|187960057|ref|NP_034881.2|/7.2864e-88/max dimerization protein 1 [Mus musculus] 56274 2928 2.166666667 1.83 -0.243633569 Down 0.243004626 Stk3 serine/threonine kinase 3 K04412|1|0.0|883|mmu:56274|serine/threonine kinase 3 GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0030295//protein kinase activator activity;GO:0004672//protein kinase activity;GO:0046872//metal ion binding GO:0035265//organ growth;GO:0007507//heart development;GO:0001892//embryonic placenta development;GO:0035162//embryonic hemopoiesis;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0007254//JNK cascade;GO:0030178//negative regulation of Wnt signaling pathway;GO:0045860//positive regulation of protein kinase activity;GO:0007399//nervous system development;GO:0001838//embryonic epithelial tube formation gi|118150664|ref|NP_062609.2|/0/serine/threonine-protein kinase 3 [Mus musculus] 110460 2076 1.823333333 2.16 0.24445298 Up 0.243004626 Acat2 acetyl-Coenzyme A acetyltransferase 2 K00626|1|0.0|784|mmu:110460|acetyl-CoA C-acetyltransferase [EC:2.3.1.9] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0003988//acetyl-CoA C-acyltransferase activity GO:0007417//central nervous system development;GO:0044248;GO:0070542//response to fatty acid;GO:0007584//response to nutrient "gi|148747461|ref|NP_033364.2|/0/acetyl-CoA acetyltransferase, cytosolic [Mus musculus]" 76809 7001 9.513333333 10.31333333 0.116487862 Up 0.242957614 Bri3bp Bri3 binding protein - GO:0016020//membrane - - "gi|148687609|gb|EDL19556.1|/2.02443e-93/Bri3 binding protein, isoform CRA_a, partial [Mus musculus]" 78668 1353 0.523333333 0.74 0.499795117 Up 0.242929407 E130112N10Rik RIKEN cDNA E130112N10 gene - - - - - 67092 2357 0.296666667 0.49 0.723938914 Up 0.242910602 Gatm glycine amidinotransferase (L-arginine:glycine amidinotransferase) K00613|1|0.0|861|mmu:67092|glycine amidinotransferase [EC:2.1.4.1] GO:0019866//organelle inner membrane;GO:0005740//mitochondrial envelope "GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0015067//amidinotransferase activity" GO:0009888//tissue development;GO:0010038//response to metal ion;GO:0009725//response to hormone;GO:0031667//response to nutrient levels;GO:0006600//creatine metabolic process;GO:0007275//multicellular organism development;GO:0006950//response to stress "gi|13385454|ref|NP_080237.1|/0/glycine amidinotransferase, mitochondrial precursor [Mus musculus]" 214764 5338 1.8 1.493333333 -0.269460675 Down 0.242844785 Edrf1 erythroid differentiation regulatory factor 1 "K15085|1|6e-06|57.0|pxy:105396092|solute carrier family 25, member 42" GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated" gi|295389569|ref|NP_835216.3|/0/erythroid differentiation-related factor 1 [Mus musculus] 22596 2571 7.77 7.09 -0.132128971 Down 0.242722554 Xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 K10885|1|0.0|1392|mmu:22596|ATP-dependent DNA helicase 2 subunit 2 "GO:0031981//nuclear lumen;GO:0000781//chromosome, telomeric region;GO:0043234//protein complex" GO:0016835//carbon-oxygen lyase activity;GO:0032550;GO:0044389//ubiquitin-like protein ligase binding;GO:0043565//sequence-specific DNA binding;GO:0000975//regulatory region DNA binding;GO:0003690//double-stranded DNA binding;GO:0003678//DNA helicase activity "GO:0030097//hemopoiesis;GO:0006351//transcription, DNA-templated;GO:0010165//response to X-ray;GO:0000726;GO:0007417//central nervous system development;GO:0070542//response to fatty acid;GO:0010720//positive regulation of cell development;GO:0006915//apoptotic process;GO:0042538//hyperosmotic salinity response" gi|160333605|ref|NP_033559.2|/0/X-ray repair cross-complementing protein 5 [Mus musculus] 17888 6050.41 8074.523333 7649.613333 -0.07799027 Down 0.242713152 Myh6 "myosin, heavy polypeptide 6, cardiac muscle, alpha" K17751|1|0.0|3335|mmu:17888|myosin heavy chain 6/7 GO:0031981//nuclear lumen;GO:0016460//myosin II complex;GO:0032432//actin filament bundle;GO:0031674//I band;GO:0005924//cell-substrate adherens junction "GO:0005198//structural molecule activity;GO:0019900//kinase binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0042802//identical protein binding;GO:0008092//cytoskeletal protein binding;GO:0003774//motor activity;GO:0046983//protein dimerization activity" GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0016055//Wnt signaling pathway;GO:0030239//myofibril assembly;GO:0043009//chordate embryonic development;GO:0008016//regulation of heart contraction;GO:0048738//cardiac muscle tissue development;GO:0009118//regulation of nucleoside metabolic process;GO:0007517//muscle organ development;GO:0009154//purine ribonucleotide catabolic process;GO:0006936//muscle contraction;GO:0003209//cardiac atrium morphogenesis;GO:0046620//regulation of organ growth;GO:0006928//movement of cell or subcellular component;GO:0003208//cardiac ventricle morphogenesis "gi|148704367|gb|EDL36314.1|/0/mCG133649, isoform CRA_b, partial [Mus musculus]" 225432 6266 2.006666667 2.356666667 0.231946728 Up 0.242684945 Rbm27 RNA binding motif protein 27 K13193|1|0.0|1346|mmu:225432|RNA-binding protein 27 - - - gi|42540747|gb|AAS19274.1|/0/peri implantation stem cell 1 [Mus musculus] 20519 3501 2.036666667 2.386666667 0.228787207 Up 0.242684945 Slc22a3 "solute carrier family 22 (organic cation transporter), member 3" "K08200|1|0.0|1074|mmu:20519|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 3" GO:0016021//integral component of membrane GO:0005488//binding;GO:0015101//organic cation transmembrane transporter activity GO:0015893//drug transport;GO:0001504//neurotransmitter uptake;GO:0044710;GO:0031667//response to nutrient levels;GO:0006812//cation transport gi|6755538|ref|NP_035525.1|/0/solute carrier family 22 member 3 [Mus musculus] 27973 764 13.13 14.12333333 0.105213712 Up 0.242628531 Vkorc1 "vitamin K epoxide reductase complex, subunit 1" K05357|1|3e-64|247|mmu:27973|vitamin-K-epoxide reductase (warfarin-sensitive) [EC:1.17.4.4] GO:0043227//membrane-bounded organelle;GO:0016020//membrane GO:0016900 GO:0009636//response to toxic substance;GO:0009719;GO:0006775;GO:0044237//cellular metabolic process;GO:0007596//blood coagulation;GO:0010033//response to organic substance gi|30519915|ref|NP_848715.1|/2.035e-63/vitamin K epoxide reductase complex subunit 1 precursor [Mus musculus] 67128 3837 19.53333333 18.22666667 -0.099887422 Down 0.242600323 Ube2g1 ubiquitin-conjugating enzyme E2G 1 K10575|1|2e-102|377|ocu:100353960|ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23] - - - gi|655869905|ref|XP_008269303.1|/1.59797e-101/PREDICTED: ubiquitin-conjugating enzyme E2 G1 [Oryctolagus cuniculus] 67856 1812 19.00666667 20.32 0.096394864 Up 0.242600323 Echdc3 enoyl Coenzyme A hydratase domain containing 3 K02366|1|7e-59|231|tsp:Tsp_04346|glucuronyl/N-acetylglucosaminyl transferase EXT1 [EC:2.4.1.224 2.4.1.225];K07511|2|5e-28|128|fca:101089898|enoyl-CoA hydratase [EC:4.2.1.17] GO:0043231//intracellular membrane-bounded organelle - - "gi|31980955|ref|NP_077170.2|/1.34913e-155/enoyl-CoA hydratase domain-containing protein 3, mitochondrial precursor [Mus musculus]" 16800 4339.57 18.78333333 17.47666667 -0.104023065 Down 0.242600323 Arhgef2 rho/rac guanine nucleotide exchange factor (GEF) 2 K12791|1|0.0|1724|mmu:16800|Rho guanine nucleotide exchange factor 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0015630//microtubule cytoskeleton;GO:0044297//cell body;GO:0030425//dendrite;GO:0001726//ruffle;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0015630//microtubule cytoskeleton;GO:0044297//cell body;GO:0030425//dendrite;GO:0001726//ruffle;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0015630//microtubule cytoskeleton;GO:0044297//cell body;GO:0030425//dendrite;GO:0001726//ruffle GO:0043169//cation binding;GO:0017048//Rho GTPase binding;GO:0008289//lipid binding;GO:0015631//tubulin binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0043169//cation binding;GO:0017048//Rho GTPase binding;GO:0008289//lipid binding;GO:0015631//tubulin binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0043169//cation binding;GO:0017048//Rho GTPase binding;GO:0008289//lipid binding;GO:0015631//tubulin binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity GO:0032989;GO:0007266//Rho protein signal transduction;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0030036//actin cytoskeleton organization;GO:0040001//establishment of mitotic spindle localization;GO:0010721//negative regulation of cell development;GO:0007019//microtubule depolymerization;GO:0000087//mitotic M phase;GO:0032989;GO:0007266//Rho protein signal transduction;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0030036//actin cytoskeleton organization;GO:0040001//establishment of mitotic spindle localization;GO:0010721//negative regulation of cell development;GO:0007019//microtubule depolymerization;GO:0000087//mitotic M phase;GO:0032989;GO:0007266//Rho protein signal transduction;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0030036//actin cytoskeleton organization;GO:0040001//establishment of mitotic spindle localization;GO:0010721//negative regulation of cell development;GO:0007019//microtubule depolymerization;GO:0000087//mitotic M phase gi|568921917|ref|XP_006501122.1|/0/PREDICTED: rho guanine nucleotide exchange factor 2 isoform X3 [Mus musculus] 12859 584 1933.136667 1832.296667 -0.077290526 Down 0.242562714 Cox5b cytochrome c oxidase subunit Vb K02265|1|1e-71|271|mmu:12859|cytochrome c oxidase subunit 5b GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding GO:0009725//response to hormone "gi|148705042|gb|EDL36989.1|/8.19941e-80/mCG18900, partial [Mus musculus]" 241327 2409 0.84 1.093333333 0.380272081 Up 0.242534507 Olfml2a olfactomedin-like 2A K04593|1|3e-51|206|tru:101062496|latrophilin 2 - GO:0042802//identical protein binding GO:0043062//extracellular structure organization gi|27370292|ref|NP_766442.1|/0/olfactomedin-like protein 2A precursor [Mus musculus] 100504347 1973 0.82 1.07 0.383914982 Up 0.242534507 Gm20187 "predicted gene, 20187" - - - - - 69030 1687 0.153333333 0.03 -2.353636955 Down 0.242534507 1810006J02Rik RIKEN cDNA 1810006J02 gene - - - - gi|148707945|gb|EDL39892.1|/4.55402e-17/mCG1047497 [Mus musculus] 67774 1777 5.746666667 6.35 0.144031223 Up 0.242478092 Borcs5 BLOC-1 related complex subunit 5 K18463|1|4e-12|75.9|loa:LOAG_01663|WASH complex subunit CCDC53 - - - gi|27754073|ref|NP_080647.2|/6.84074e-104/loss of heterozygosity 12 chromosomal region 1 protein homolog isoform 2 [Mus musculus] 73095 3181 37.76 40.14666667 0.088421443 Up 0.242459288 Slc25a42 "solute carrier family 25, member 42" "K15085|1|1e-159|566|mmu:73095|solute carrier family 25, member 42" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0000295//adenine nucleotide transmembrane transporter activity;GO:0017110//nucleoside-diphosphatase activity GO:0044763;GO:0015695//organic cation transport;GO:0015880//coenzyme A transport gi|564388675|ref|XP_006253012.1|/1.0288e-160/PREDICTED: mitochondrial coenzyme A transporter SLC25A42 isoform X2 [Rattus norvegicus] 19338 3488 3.833333333 3.39 -0.177314182 Down 0.242412276 Rab33b "RAB33B, member RAS oncogene family" K07920|1|2e-116|423|mmu:19338|Ras-related protein Rab-33B GO:0044431//Golgi apparatus part GO:0032550 GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization;GO:0000045//autophagosome assembly;GO:0032386//regulation of intracellular transport gi|74202820|dbj|BAE37491.1|/2.34032e-136/unnamed protein product [Mus musculus] 16826 2524 3.69 3.25 -0.183181098 Down 0.242412276 Ldb2 LIM domain binding 2 K15617|1|1e-116|423|isc:IscW_ISCW010935|LIM domain-binding protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0000989//transcription factor activity, transcription factor binding;GO:0019904//protein domain specific binding" GO:0001894//tissue homeostasis;GO:0008544//epidermis development;GO:0019827//stem cell population maintenance;GO:0006366//transcription from RNA polymerase II promoter;GO:0044085 gi|514451912|ref|XP_003465082.2|/0/PREDICTED: LIM domain-binding protein 2 isoform X1 [Cavia porcellus] 14198 1002 0.87 0.636666667 -0.450477169 Down 0.242384069 Fhit fragile histidine triad gene K01522|1|1e-82|308|mmu:14198|bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29] GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0004551//nucleotide diphosphatase activity;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0004551//nucleotide diphosphatase activity;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0004551//nucleotide diphosphatase activity GO:0072331//signal transduction by p53 class mediator;GO:0006259//DNA metabolic process;GO:0031330;GO:0015961//diadenosine polyphosphate catabolic process;GO:0072331//signal transduction by p53 class mediator;GO:0006259//DNA metabolic process;GO:0031330;GO:0015961//diadenosine polyphosphate catabolic process;GO:0072331//signal transduction by p53 class mediator;GO:0006259//DNA metabolic process;GO:0031330;GO:0015961//diadenosine polyphosphate catabolic process gi|815930055|ref|NP_001295214.1|/8.41771e-122/bis(5'-adenosyl)-triphosphatase isoform 1 [Mus musculus] 269951 1718 1072.493333 1136.816667 0.084030931 Up 0.242365264 Idh2 "isocitrate dehydrogenase 2 (NADP+), mitochondrial" K00031|1|0.0|932|mmu:269951|isocitrate dehydrogenase [EC:1.1.1.42] GO:0019866//organelle inner membrane;GO:0044429 GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding GO:0050896//response to stimulus;GO:0043648//dicarboxylic acid metabolic process;GO:0044262//cellular carbohydrate metabolic process;GO:0072350//tricarboxylic acid metabolic process;GO:0009060//aerobic respiration gi|537205233|gb|ERE79866.1|/0/isocitrate dehydrogenase [Cricetulus griseus] 67264 641 1157.003333 1093.713333 -0.081158369 Down 0.242355861 Ndufb8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8 K03964|1|1e-109|397|mmu:67264|NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8 GO:0031224//intrinsic component of membrane;GO:0005746//mitochondrial respiratory chain GO:0050136//NADH dehydrogenase (quinone) activity GO:0051234//establishment of localization;GO:0022904//respiratory electron transport chain "gi|13385558|ref|NP_080337.1|/1.0732e-108/NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial precursor [Mus musculus]" 66594 436 1053.03 1113.14 0.080088514 Up 0.242355861 Uqcr11 "ubiquinol-cytochrome c reductase, complex III subunit XI" K00420|1|6e-26|117|mmu:66594|ubiquinol-cytochrome c reductase subunit 10 GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane GO:0015078//hydrogen ion transmembrane transporter activity GO:0006818//hydrogen transport;GO:0006811//ion transport;GO:0044710;GO:0006091//generation of precursor metabolites and energy gi|589930871|ref|XP_006978242.1|/4.09872e-28/PREDICTED: cytochrome b-c1 complex subunit 10-like [Peromyscus maniculatus bairdii] 243983 2407 5.1 5.64 0.145197916 Up 0.242327654 Zdhhc13 "zinc finger, DHHC domain containing 13" K20032|1|0.0|1268|mmu:243983|palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225] GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0012506//vesicle membrane "GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0046914//transition metal ion binding;GO:0060089;GO:0046873//metal ion transmembrane transporter activity" GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0070838//divalent metal ion transport gi|27229145|ref|NP_082307.1|/0/palmitoyltransferase ZDHHC13 [Mus musculus] 14281 2107 5.406666667 4.866666667 -0.15180545 Down 0.242327654 Fos FBJ osteosarcoma oncogene K04379|1|4e-164|580|mmu:14281|proto-oncogene protein c-fos GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0042995//cell projection GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0043566//structure-specific DNA binding;GO:0046332//SMAD binding GO:0044703;GO:0009605//response to external stimulus;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0051592//response to calcium ion;GO:0046683//response to organophosphorus;GO:0000302//response to reactive oxygen species;GO:0051384//response to glucocorticoid;GO:0007519//skeletal muscle tissue development;GO:0009314//response to radiation;GO:0002237//response to molecule of bacterial origin gi|6753894|ref|NP_034364.1|/3.63452e-163/proto-oncogene c-Fos [Mus musculus] 270156 3335 4.746666667 5.283333333 0.154533694 Up 0.242327654 AU019823 expressed sequence AU019823 - - - - "gi|148693799|gb|EDL25746.1|/1.2049e-105/expressed sequence AU019823, partial [Mus musculus]" 104458 2140 17.15 18.44 0.104630079 Up 0.242196021 Rars arginyl-tRNA synthetase K01887|1|0.0|1318|mmu:104458|arginyl-tRNA synthetase [EC:6.1.1.19] GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity;GO:0016597//amino acid binding GO:0006418//tRNA aminoacylation for protein translation "gi|262118273|ref|NP_080212.2|/0/arginine--tRNA ligase, cytoplasmic [Mus musculus]" 214580 1130 13.87333333 12.89666667 -0.105316236 Down 0.242130204 Pstk phosphoseryl-tRNA kinase K10837|1|0.0|685|mmu:214580|O-phosphoseryl-tRNA(Sec) kinase [EC:2.7.1.164] - - - - 629059 3557 4.903333333 4.403333333 -0.15516678 Down 0.242083192 Fam124a "family with sequence similarity 124, member A" - - - - gi|345110602|ref|NP_001230786.1|/0/protein FAM124A [Mus musculus] 69807 3193.07 4.233333333 4.736666667 0.162078058 Up 0.242083192 Trim32 tripartite motif-containing 32 K10607|1|0.0|1239|mmu:69807|tripartite motif-containing protein 32 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0005859//muscle myosin complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005859//muscle myosin complex GO:0032182//ubiquitin-like protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0003676//nucleic acid binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0032182//ubiquitin-like protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0003676//nucleic acid binding;GO:0019787//ubiquitin-like protein transferase activity GO:0040017//positive regulation of locomotion;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0010720//positive regulation of cell development;GO:0006915//apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0034097//response to cytokine;GO:0016567//protein ubiquitination;GO:0051726//regulation of cell cycle;GO:0009416//response to light stimulus;GO:0006508//proteolysis;GO:0016049//cell growth;GO:0009896;GO:0016477//cell migration;GO:0030182//neuron differentiation;GO:0040017//positive regulation of locomotion;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0010720//positive regulation of cell development;GO:0006915//apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0034097//response to cytokine;GO:0016567//protein ubiquitination;GO:0051726//regulation of cell cycle;GO:0009416//response to light stimulus;GO:0006508//proteolysis;GO:0016049//cell growth;GO:0009896;GO:0016477//cell migration;GO:0030182//neuron differentiation "gi|148699134|gb|EDL31081.1|/0/tripartite motif protein 32, isoform CRA_a, partial [Mus musculus]" 68342 657 716.14 757.9066667 0.081778546 Up 0.242064388 Ndufb10 "NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10" K03966|1|2e-83|310|mmu:68342|NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10 GO:0005746//mitochondrial respiratory chain - GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy gi|58037109|ref|NP_080960.1|/1.42399e-82/NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 [Mus musculus] 67445 1383 1.726666667 1.423333333 -0.278716028 Down 0.242045583 C1qtnf4 C1q and tumor necrosis factor related protein 4 K19470|1|1e-19|100|bfo:BRAFLDRAFT_91625|complement C1q tumor necrosis factor-related protein 6;K18744|3|1e-16|90.1|ngi:103737773|caprin-2 GO:0044421 GO:0005102//receptor binding - gi|635013582|ref|XP_007997484.1|/1.59309e-163/PREDICTED: complement C1q tumor necrosis factor-related protein 4 [Chlorocebus sabaeus] 242860 5562 2.413333333 2.79 0.209237925 Up 0.24203618 Rsbn1l round spermatid basic protein 1-like K18024|1|1e-178|630|phi:102108239|tyrosine-protein phosphatase non-receptor type 12/18/22 [EC:3.1.3.48] - - - gi|124430547|ref|NP_001074446.1|/0/round spermatid basic protein 1-like protein [Mus musculus] 73181 4036 2.85 2.466666667 -0.208399149 Down 0.24203618 Nfatc4 "nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4" "K17334|1|0.0|1314|mmu:73181|nuclear factor of activated T-cells, cytoplasmic 4" GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part GO:0005102//receptor binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0005102//receptor binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding GO:0001525//angiogenesis;GO:0015980//energy derivation by oxidation of organic compounds;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0009411//response to UV;GO:0050804//modulation of synaptic transmission;GO:0042692//muscle cell differentiation;GO:0006952//defense response;GO:0010226//response to lithium ion;GO:0001525//angiogenesis;GO:0015980//energy derivation by oxidation of organic compounds;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0009411//response to UV;GO:0050804//modulation of synaptic transmission;GO:0042692//muscle cell differentiation;GO:0006952//defense response;GO:0010226//response to lithium ion "gi|270047506|ref|NP_076188.3|/0/nuclear factor of activated T-cells, cytoplasmic 4 isoform 1 [Mus musculus]" 80903 3040 2.853333333 2.47 -0.208137254 Down 0.24203618 Fgf16 fibroblast growth factor 16 K04358|1|9e-118|427|lve:103072981|fibroblast growth factor GO:0044421 GO:0005102//receptor binding GO:0070342//brown fat cell proliferation;GO:0009628//response to abiotic stimulus;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009653//anatomical structure morphogenesis gi|126116563|ref|NP_085117.2|/7.91016e-117/fibroblast growth factor 16 [Mus musculus] 17215 2886 2.136666667 2.496666667 0.224641362 Up 0.241942157 Mcm3 minichromosome maintenance complex component 3 K02541|1|0.0|1452|mmu:17215|DNA replication licensing factor MCM3 [EC:3.6.4.12] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0032550;GO:0003676//nucleic acid binding;GO:0004386//helicase activity GO:0044763;GO:0006259//DNA metabolic process gi|33859484|ref|NP_032589.1|/0/DNA replication licensing factor MCM3 [Mus musculus] 70802 3906.12 2.183333333 2.543333333 0.22018815 Up 0.241942157 Pwwp2a PWWP domain containing 2A - - - - gi|255982568|ref|NP_001157703.1|/0/PWWP domain-containing protein 2A isoform a [Mus musculus] 320692 3177 2.176666667 2.54 0.222708006 Up 0.241942157 9430037G07Rik RIKEN cDNA 9430037G07 gene "K03872|1|5e-42|176|phd:102320935|transcription elongation factor B, polypeptide 1" - - - - 109674 3589.6 2.173333333 2.533333333 0.221127454 Up 0.241942157 Ampd2 adenosine monophosphate deaminase 2 K01490|1|0.0|1593|mmu:109674|AMP deaminase [EC:3.5.4.6] GO:0044444//cytoplasmic part "GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0043169//cation binding;GO:0003824//catalytic activity" GO:0006188//IMP biosynthetic process;GO:0006188//IMP biosynthetic process;GO:0009112;GO:0006188//IMP biosynthetic process gi|564338426|ref|XP_006233230.1|/0/PREDICTED: AMP deaminase 2 isoform X1 [Rattus norvegicus] 244237 2977 0.183333333 0.35 0.932885804 Up 0.24187634 Tnfrsf26 "tumor necrosis factor receptor superfamily, member 26" K05161|1|7e-97|358|mmu:244237|tumor necrosis factor receptor superfamily member 26;K04722|3|2e-25|120|mze:101465040|tumor necrosis factor receptor superfamily member 10;K01883|4|4e-24|116|fch:102058256|cysteinyl-tRNA synthetase [EC:6.1.1.16] GO:0031224//intrinsic component of membrane - - "gi|148686275|gb|EDL18222.1|/4.41978e-96/tumor necrosis factor receptor superfamily, member 26, partial [Mus musculus]" 80886 2442 18.11666667 19.38666667 0.097747234 Up 0.241763511 Senp3 SUMO/sentrin specific peptidase 3 K08593|1|0.0|1016|mmu:80886|sentrin-specific protease 3 [EC:3.4.22.68] GO:0044665//MLL1/2 complex;GO:0044665//MLL1/2 complex GO:0019783//ubiquitin-like protein-specific protease activity;GO:0005488//binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0005488//binding GO:0019538//protein metabolic process;GO:0019538//protein metabolic process gi|254939659|ref|NP_109627.3|/0/sentrin-specific protease 3 [Mus musculus] 66917 2205 9.096666667 9.88 0.119173053 Up 0.241754109 Chordc1 "cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1" K16729|1|1e-165|585|mmu:66917|cysteine and histidine-rich domain-containing protein 1 - GO:0031072//heat shock protein binding;GO:0046914//transition metal ion binding GO:0006457//protein folding;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0048583;GO:0046605//regulation of centrosome cycle gi|13385324|ref|NP_080120.1|/1.1899e-164/cysteine and histidine-rich domain-containing protein 1 [Mus musculus] 231841 3397.77 3.79 4.25 0.165264993 Up 0.241697695 Brat1 BRCA1-associated ATM activator 1 - - - - - 68303 2949 4.25 3.786666667 -0.166534412 Down 0.241697695 Fam114a1 "family with sequence similarity 114, member A1" - GO:0044424 - - gi|170650597|ref|NP_080943.3|/0/protein Noxp20 [Mus musculus] 97212 3835 525.0833333 555.08 0.080149309 Up 0.241697695 Hadha "hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit" K07515|1|0.0|1340|mmu:97212|enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211] GO:0031981//nuclear lumen;GO:0019866//organelle inner membrane;GO:0005759//mitochondrial matrix "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0048037//cofactor binding;GO:0016836//hydro-lyase activity;GO:0016408//C-acyltransferase activity" GO:0009062//fatty acid catabolic process;GO:0043434//response to peptide hormone "gi|33859811|ref|NP_849209.1|/0/trifunctional enzyme subunit alpha, mitochondrial precursor [Mus musculus]" 434341 6945 0.946666667 1.21 0.354078618 Up 0.24167889 Nlrc5 "NLR family, CARD domain containing 5" "K08060|1|9e-45|186|lcm:102357559|class II, major histocompatibility complex, transactivator" - - - gi|254692966|ref|NP_001028379.2|/0/protein NLRC5 [Mus musculus] 69504 2075 1.206666667 0.946666667 -0.350098768 Down 0.24167889 Zfp932 zinc finger protein 932 K09228|1|0.0|775|rno:102550944|KRAB domain-containing zinc finger protein - - - gi|295293092|ref|NP_663538.2|/0/zinc finger protein 431 [Mus musculus] 22710 3164 1.196666667 0.94 -0.348288681 Down 0.24167889 Zfp52 zinc finger protein 52 K09228|1|0.0|1573|mmu:22710|KRAB domain-containing zinc finger protein GO:0044464 GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|122937377|ref|NP_653098.2|/0/zinc finger protein 52 [Mus musculus] 668218 1978 0.953333333 1.213333333 0.347923303 Up 0.24167889 Bin2 bridging integrator 2 K20119|1|0.0|679|mmu:668218|bridging integrator 2 GO:0044424 - GO:0044763;GO:0016043//cellular component organization gi|395627630|ref|NP_001257466.1|/0/bridging integrator 2 [Mus musculus] 15929 1335 479.25 506.7433333 0.080476772 Up 0.241622475 Idh3g "isocitrate dehydrogenase 3 (NAD+), gamma" K00030|1|0.0|661|mmu:15929|isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] GO:0031981//nuclear lumen;GO:0030062//mitochondrial tricarboxylic acid cycle enzyme complex GO:0032550;GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding GO:0043648//dicarboxylic acid metabolic process;GO:0040007//growth;GO:0072350//tricarboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0019674//NAD metabolic process "gi|6680345|ref|NP_032349.1|/0/isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial precursor [Mus musculus]" 240444 2815 36.41666667 34.14 -0.093135816 Down 0.241584866 Kcng2 "potassium voltage-gated channel, subfamily G, member 2" K04901|1|0.0|686|mmu:240444|potassium voltage-gated channel subfamily G member 2 GO:0005886//plasma membrane GO:0005249//voltage-gated potassium channel activity GO:0030073//insulin secretion;GO:0015980//energy derivation by oxidation of organic compounds;GO:0030001//metal ion transport;GO:0044057 gi|298566262|ref|NP_001177302.1|/0/potassium voltage-gated channel subfamily G member 2 [Mus musculus] 12460 1057 17.5 18.76333333 0.100561225 Up 0.241472037 Ccs copper chaperone for superoxide dismutase K04569|1|9e-158|558|mmu:12460|copper chaperone for superoxide dismutase - - - gi|8393066|ref|NP_058588.1|/7.42016e-157/copper chaperone for superoxide dismutase [Mus musculus] 66377 414 436.3333333 411.4866667 -0.084585007 Down 0.241472037 Ndufc1 "NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1" K03967|1|2e-37|155|mmu:66377|NADH dehydrogenase (ubiquinone) 1 subunit C1 GO:0031224//intrinsic component of membrane;GO:0005746//mitochondrial respiratory chain GO:0050136//NADH dehydrogenase (quinone) activity GO:0051234//establishment of localization;GO:0022904//respiratory electron transport chain "gi|13384946|ref|NP_079799.1|/2.36285e-36/NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor [Mus musculus]" 22064 3342 0.413333333 0.236666667 -0.804449191 Down 0.241472037 Trpc2 "transient receptor potential cation channel, subfamily C, member 2" K04965|1|0.0|1420|mmu:22064|transient receptor potential cation channel subfamily C member 2 - - - gi|158187554|ref|NP_001103367.1|/0/short transient receptor potential channel 2 [Mus musculus] 70359 2800 5.706666667 6.293333333 0.141176063 Up 0.24144383 Gtpbp3 GTP binding protein 3 K03650|1|0.0|832|mmu:70359|tRNA modification GTPase [EC:3.6.-.-] GO:0043231//intracellular membrane-bounded organelle GO:0017111//nucleoside-triphosphatase activity;GO:0043169//cation binding;GO:0032550 GO:0009154//purine ribonucleotide catabolic process;GO:0008033//tRNA processing "gi|33414589|ref|NP_115933.2|/0/tRNA modification GTPase GTPBP3, mitochondrial precursor [Mus musculus]" 57913 2900 0.466666667 0.68 0.543142325 Up 0.241434428 Pidd1 p53 induced death domain protein 1 K10130|1|0.0|1539|mmu:57913|leucine-rich repeats and death domain-containing protein GO:0043231//intracellular membrane-bounded organelle - "GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006915//apoptotic process" gi|12083587|ref|NP_073145.1|/0/p53-induced death domain-containing protein 1 [Mus musculus] 13447 5068 0.466666667 0.676666667 0.5360529 Up 0.241434428 Doc2b "double C2, beta" K19917|1|0.0|684|mmu:13447|double C2-like domain-containing protein beta - - - - 20682 4146 0.886666667 0.653333333 -0.440572591 Down 0.241378013 Sox9 SRY (sex determining region Y)-box 9 K18435|1|0.0|884|mmu:20682|transcription factor SOX9 (SOX group E) GO:0031981//nuclear lumen;GO:0043234//protein complex "GO:0051018//protein kinase A binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0008134//transcription factor binding;GO:0016301//kinase activity;GO:0000976//transcription regulatory region sequence-specific DNA binding" GO:0006915//apoptotic process;GO:0072497;GO:0007542;GO:0070555//response to interleukin-1;GO:0071363//cellular response to growth factor stimulus;GO:0060516//primary prostatic bud elongation;GO:0009612//response to mechanical stimulus;GO:0038127//ERBB signaling pathway;GO:0065003;GO:0016337//single organismal cell-cell adhesion;GO:0000165//MAPK cascade;GO:0051726//regulation of cell cycle;GO:0002376//immune system process;GO:0008406//gonad development;GO:0009896;GO:0008284//positive regulation of cell proliferation;GO:0071417//cellular response to organonitrogen compound;GO:0003179//heart valve morphogenesis;GO:0014031//mesenchymal cell development;GO:0008285//negative regulation of cell proliferation;GO:0031214//biomineral tissue development;GO:0048232//male gamete generation;GO:0000904//cell morphogenesis involved in differentiation;GO:0007417//central nervous system development;GO:0060219//camera-type eye photoreceptor cell differentiation;GO:0031016//pancreas development;GO:0032526//response to retinoic acid;GO:0043062//extracellular structure organization;GO:0030277//maintenance of gastrointestinal epithelium;GO:0016568//chromatin modification;GO:0001889//liver development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0034728//nucleosome organization;GO:0048568//embryonic organ development;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0001656//metanephros development;GO:0045665//negative regulation of neuron differentiation;GO:0030855//epithelial cell differentiation;GO:0060349//bone morphogenesis;GO:0008544//epidermis development;GO:0003007//heart morphogenesis;GO:0001932//regulation of protein phosphorylation;GO:0009967//positive regulation of signal transduction;GO:0030178//negative regulation of Wnt signaling pathway;GO:0019827//stem cell population maintenance;GO:0021781//glial cell fate commitment;GO:0051094//positive regulation of developmental process;GO:0072079//nephron tubule formation;GO:0045445//myoblast differentiation;GO:0030279//negative regulation of ossification;GO:0006366//transcription from RNA polymerase II promoter;GO:0070849//response to epidermal growth factor;GO:0002063//chondrocyte development;GO:0010631//epithelial cell migration;GO:0031128//developmental induction gi|60360276|dbj|BAD90382.1|/0/mKIAA4243 protein [Mus musculus] 55992 2883.93 12.31666667 13.27666667 0.108281115 Up 0.241293392 Trim3 tripartite motif-containing 3 K11997|1|0.0|1497|mmu:55992|tripartite motif-containing protein 2/3 GO:0005768//endosome;GO:0005768//endosome;GO:0005768//endosome;GO:0005768//endosome GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0045184//establishment of protein localization;GO:0045184//establishment of protein localization;GO:0045184//establishment of protein localization;GO:0045184//establishment of protein localization gi|552953687|ref|NP_001272802.1|/0/tripartite motif-containing protein 3 isoform b [Mus musculus] 668158 1547 12.73333333 11.77666667 -0.112678889 Down 0.241293392 Ccdc85c coiled-coil domain containing 85C K16758|1|6e-24|114|xma:102228104|coiled-coil domain-containing protein 85B GO:0043296//apical junction complex - GO:0021543//pallium development gi|229576815|ref|NP_001153382.1|/3.07629e-158/coiled-coil domain-containing protein 85C [Mus musculus] 17920 7868 1.9 1.586666667 -0.260000346 Down 0.241265185 Myo6 myosin VI K10358|1|0.0|1828|mmu:17920|myosin VI "GO:0043005//neuron projection;GO:0005884//actin filament;GO:0016020//membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0044297//cell body;GO:0001726//ruffle;GO:0005635//nuclear envelope;GO:0044451" GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0003779//actin binding GO:0042221//response to chemical;GO:0051602//response to electrical stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0006835//dicarboxylic acid transport;GO:0042770//signal transduction in response to DNA damage;GO:0060113//inner ear receptor cell differentiation;GO:0031175//neuron projection development;GO:0006886//intracellular protein transport;GO:0050954//sensory perception of mechanical stimulus;GO:0016192//vesicle-mediated transport;GO:0042471//ear morphogenesis;GO:0050804//modulation of synaptic transmission;GO:0046903//secretion;GO:0044708//single-organism behavior gi|261823961|ref|NP_001034635.2|/0/unconventional myosin-VI [Mus musculus] 207952 3379.3 1.586666667 1.896666667 0.257467079 Up 0.241265185 Klhl25 kelch-like 25 K10462|1|0.0|1172|mmu:207952|kelch-like protein 25/37 (ectoderm-neural cortex protein) GO:0044424;GO:0044424;GO:0044424 - - gi|33354238|ref|NP_877583.1|/0/kelch-like protein 25 [Mus musculus] 12183 2068 8.753333333 9.523333333 0.12163412 Up 0.241199368 Bpgm "2,3-bisphosphoglycerate mutase" K01837|1|1e-149|532|mmu:12183|bisphosphoglycerate mutase [EC:5.4.2.4 5.4.2.11 3.1.3.13] - "GO:0034416//bisphosphoglycerate phosphatase activity;GO:0016868//intramolecular transferase activity, phosphotransferases" GO:0030218//erythrocyte differentiation;GO:0006007//glucose catabolic process gi|6680806|ref|NP_031589.1|/1.10839e-148/bisphosphoglycerate mutase [Mus musculus] 59007 2901 9.603333333 8.836666667 -0.12003299 Down 0.241199368 Ngly1 N-glycanase 1 K01456|1|0.0|1251|mmu:59007|peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase [EC:3.5.1.52] GO:0043231//intracellular membrane-bounded organelle "GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0043169//cation binding" GO:0009100//glycoprotein metabolic process gi|31981178|ref|NP_067479.2|/0/peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase [Mus musculus] 71779 4596.13 9.8 9.033333333 -0.117523303 Down 0.241199368 8-Mar membrane-associated ring finger (C3HC4) 8 K10656|1|6e-156|555|rno:312656|E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27] GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0005769//early endosome;GO:0012506//vesicle membrane;GO:0031224//intrinsic component of membrane;GO:0000323//lytic vacuole;GO:0031982//vesicle;GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0005769//early endosome;GO:0012506//vesicle membrane;GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0005769//early endosome;GO:0012506//vesicle membrane GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0042287//MHC protein binding;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0042287//MHC protein binding;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0042287//MHC protein binding;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0042287//MHC protein binding GO:0010558;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0016567//protein ubiquitination;GO:0010558;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0016567//protein ubiquitination;GO:0010558;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0016567//protein ubiquitination;GO:0010558;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0016567//protein ubiquitination gi|27229135|ref|NP_082196.1|/5.06857e-155/E3 ubiquitin-protein ligase MARCH8 isoform 1 [Mus musculus] 71790 1874 0.313333333 0.503333333 0.683815888 Up 0.241199368 Anxa9 annexin A9 K17090|1|0.0|657|mmu:71790|annexin A9 GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0004888//transmembrane signaling receptor activity;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0004888//transmembrane signaling receptor activity GO:0007155//cell adhesion;GO:0007155//cell adhesion "gi|148706851|gb|EDL38798.1|/0/annexin A9, isoform CRA_a, partial [Mus musculus]" 78103 2854 0.313333333 0.503333333 0.683815888 Up 0.241199368 8430431K14Rik RIKEN cDNA 8430431K14 gene - - - - gi|148709764|gb|EDL41710.1|/1.67247e-52/mCG148462 [Mus musculus] 74477 4332 0.836666667 1.083333333 0.372752354 Up 0.241133551 4933427D14Rik RIKEN cDNA 4933427D14 gene - - - - - 56644 2204.74 0.876666667 1.13 0.366222474 Up 0.241133551 Clec7a "C-type lectin domain family 7, member a" K10074|1|2e-104|382|rno:502902|C-type lectin domain family 7 member A GO:0009986//cell surface;GO:0009986//cell surface GO:0030247//polysaccharide binding;GO:0001873;GO:0030247//polysaccharide binding;GO:0001873 GO:0001878//response to yeast;GO:0006909//phagocytosis;GO:0001819//positive regulation of cytokine production;GO:0002263//cell activation involved in immune response;GO:0007155//cell adhesion;GO:0002238//response to molecule of fungal origin;GO:0002220;GO:0001878//response to yeast;GO:0006909//phagocytosis;GO:0001819//positive regulation of cytokine production;GO:0002263//cell activation involved in immune response;GO:0007155//cell adhesion;GO:0002238//response to molecule of fungal origin;GO:0002220 gi|830260069|ref|NP_001296566.1|/6.20742e-102/C-type lectin domain family 7 member A 2 [Mus musculus] 18605 6791.45 0.75 0.993333333 0.405387329 Up 0.241124149 Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 K01513|1|0.0|1797|mmu:18605|ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9] GO:0031224//intrinsic component of membrane;GO:0044464;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0044421 GO:0038024//cargo receptor activity;GO:0005102//receptor binding;GO:0004527//exonuclease activity;GO:0004551//nucleotide diphosphatase activity;GO:0032550;GO:0042802//identical protein binding;GO:0001871;GO:0043169//cation binding;GO:0038024//cargo receptor activity;GO:0005102//receptor binding;GO:0004527//exonuclease activity;GO:0004551//nucleotide diphosphatase activity;GO:0032550;GO:0042802//identical protein binding;GO:0001871;GO:0043169//cation binding;GO:0038024//cargo receptor activity;GO:0005102//receptor binding;GO:0004527//exonuclease activity;GO:0004551//nucleotide diphosphatase activity;GO:0032550;GO:0042802//identical protein binding;GO:0001871;GO:0043169//cation binding GO:0010829//negative regulation of glucose transport;GO:0009888//tissue development;GO:0005978//glycogen biosynthetic process;GO:0016049//cell growth;GO:0001503//ossification;GO:0001933//negative regulation of protein phosphorylation;GO:0045444//fat cell differentiation;GO:0048771//tissue remodeling;GO:0019915//lipid storage;GO:0015698//inorganic anion transport;GO:0006790//sulfur compound metabolic process;GO:0002376//immune system process;GO:0072502;GO:0009141//nucleoside triphosphate metabolic process;GO:0008286//insulin receptor signaling pathway;GO:0010829//negative regulation of glucose transport;GO:0009888//tissue development;GO:0005978//glycogen biosynthetic process;GO:0016049//cell growth;GO:0001503//ossification;GO:0001933//negative regulation of protein phosphorylation;GO:0045444//fat cell differentiation;GO:0048771//tissue remodeling;GO:0019915//lipid storage;GO:0015698//inorganic anion transport;GO:0006790//sulfur compound metabolic process;GO:0002376//immune system process;GO:0072502;GO:0009141//nucleoside triphosphate metabolic process;GO:0008286//insulin receptor signaling pathway;GO:0010829//negative regulation of glucose transport;GO:0009888//tissue development;GO:0005978//glycogen biosynthetic process;GO:0016049//cell growth;GO:0001503//ossification;GO:0001933//negative regulation of protein phosphorylation;GO:0045444//fat cell differentiation;GO:0048771//tissue remodeling;GO:0019915//lipid storage;GO:0015698//inorganic anion transport;GO:0006790//sulfur compound metabolic process;GO:0002376//immune system process;GO:0072502;GO:0009141//nucleoside triphosphate metabolic process;GO:0008286//insulin receptor signaling pathway gi|817477963|ref|NP_001295256.1|/0/ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform 1 [Mus musculus] 57740 2006 0.733333333 0.976666667 0.413397141 Up 0.241124149 Stk32c serine/threonine kinase 32C K08793|1|0.0|783|mmu:57740|serine/threonine kinase 32 [EC:2.7.11.1] - GO:0043169//cation binding;GO:0004672//protein kinase activity;GO:0032550;GO:0043169//cation binding;GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|7670350|dbj|BAA95027.1|/0/unnamed protein product [Mus musculus] 319583 4081 0.963333333 0.723333333 -0.41337445 Down 0.241124149 Lig4 "ligase IV, DNA, ATP-dependent" K10777|1|0.0|1841|mmu:319583|DNA ligase 4 [EC:6.5.1.1] - - - gi|84794637|ref|NP_795927.2|/0/DNA ligase 4 [Mus musculus] 619301 1227 0.733333333 0.973333333 0.408464845 Up 0.241124149 Tmem253 transmembrane protein 253 - GO:0031224//intrinsic component of membrane - - gi|85702141|ref|NP_001028977.1|/1.62293e-108/transmembrane protein 253 [Mus musculus] 14735 2325 6.9 7.56 0.131789873 Up 0.241058332 Gpc4 glypican 4 K08110|1|0.0|1037|mmu:14735|glypican 4 GO:0005764//lysosome;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0031012//extracellular matrix;GO:0044431//Golgi apparatus part;GO:0044421 GO:0043168//anion binding GO:0044238//primary metabolic process;GO:0006026;GO:0006790//sulfur compound metabolic process;GO:0044699;GO:0006023;GO:0032502//developmental process gi|238624186|ref|NP_032176.2|/0/glypican-4 precursor [Mus musculus] 14118 9900 7.523333333 6.863333333 -0.132462589 Down 0.241058332 Fbn1 fibrillin 1 K06825|1|0.0|6138|mmu:14118|fibrillin 1 GO:0043205//fibril GO:0046872//metal ion binding;GO:0005198//structural molecule activity GO:0048731//system development;GO:0030514//negative regulation of BMP signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0044767//single-organism developmental process gi|755498697|ref|XP_011237592.1|/0/PREDICTED: fibrillin-1 isoform X2 [Mus musculus] 93790 3269 7.973333333 7.31 -0.125311578 Down 0.241058332 Nipa2 non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human) K19364|1|5e-46|189|hgl:101714525|magnesium transporter NIPA1 GO:0005768//endosome;GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0031224//intrinsic component of membrane GO:0046873//metal ion transmembrane transporter activity;GO:0046873//metal ion transmembrane transporter activity;GO:0046873//metal ion transmembrane transporter activity;GO:0046873//metal ion transmembrane transporter activity;GO:0046873//metal ion transmembrane transporter activity GO:0070838//divalent metal ion transport;GO:0070838//divalent metal ion transport;GO:0070838//divalent metal ion transport;GO:0070838//divalent metal ion transport;GO:0070838//divalent metal ion transport "gi|148689926|gb|EDL21873.1|/4.97744e-165/non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human), isoform CRA_b, partial [Mus musculus]" 11636 2087.58 367.1866667 347.1033333 -0.081148453 Down 0.241030125 Ak1 adenylate kinase 1 K00939|1|2e-103|379|mmu:11636|adenylate kinase [EC:2.7.4.3] GO:0016020//membrane;GO:0030016//myofibril;GO:0031514//motile cilium;GO:0044447;GO:0016020//membrane;GO:0030016//myofibril;GO:0031514//motile cilium;GO:0044447;GO:0016020//membrane;GO:0030016//myofibril;GO:0031514//motile cilium;GO:0044447;GO:0016020//membrane;GO:0030016//myofibril;GO:0031514//motile cilium;GO:0044447 "GO:0016301//kinase activity;GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0016301//kinase activity;GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0016301//kinase activity;GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0016301//kinase activity;GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0014041//regulation of neuron maturation;GO:0009152//purine ribonucleotide biosynthetic process;GO:0046102;GO:0010827//regulation of glucose transport;GO:0043627//response to estrogen;GO:0006144//purine nucleobase metabolic process;GO:0022402//cell cycle process;GO:0022037//metencephalon development;GO:0021988//olfactory lobe development;GO:0014041//regulation of neuron maturation;GO:0009152//purine ribonucleotide biosynthetic process;GO:0046102;GO:0010827//regulation of glucose transport;GO:0043627//response to estrogen;GO:0006144//purine nucleobase metabolic process;GO:0022402//cell cycle process;GO:0022037//metencephalon development;GO:0021988//olfactory lobe development;GO:0014041//regulation of neuron maturation;GO:0009152//purine ribonucleotide biosynthetic process;GO:0046102;GO:0010827//regulation of glucose transport;GO:0043627//response to estrogen;GO:0006144//purine nucleobase metabolic process;GO:0022402//cell cycle process;GO:0022037//metencephalon development;GO:0021988//olfactory lobe development;GO:0014041//regulation of neuron maturation;GO:0009152//purine ribonucleotide biosynthetic process;GO:0046102;GO:0010827//regulation of glucose transport;GO:0043627//response to estrogen;GO:0006144//purine nucleobase metabolic process;GO:0022402//cell cycle process;GO:0022037//metencephalon development;GO:0021988//olfactory lobe development gi|311771688|ref|NP_001185719.1|/1.45e-103/adenylate kinase isoenzyme 1 isoform 2 [Mus musculus] 18412 2017.86 356.93 376.6933333 0.077749336 Up 0.240992516 Sqstm1 sequestosome 1 K14381|1|0.0|852|mmu:18412|sequestosome 1 GO:0031981//nuclear lumen;GO:0016234//inclusion body;GO:0031982//vesicle;GO:0000323//lytic vacuole;GO:0035770//ribonucleoprotein granule;GO:0005768//endosome;GO:0016234//inclusion body;GO:0031982//vesicle;GO:0000323//lytic vacuole;GO:0035770//ribonucleoprotein granule;GO:0005768//endosome "GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0031593//polyubiquitin binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0019901//protein kinase binding;GO:0031593//polyubiquitin binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding" GO:0033036;GO:0007265//Ras protein signal transduction;GO:0006366//transcription from RNA polymerase II promoter;GO:0012501//programmed cell death;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0051259//protein oligomerization;GO:0001932//regulation of protein phosphorylation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0044765//single-organism transport;GO:0048869//cellular developmental process;GO:0006914//autophagy;GO:0019941//modification-dependent protein catabolic process;GO:0012501//programmed cell death;GO:0051259//protein oligomerization;GO:0001932//regulation of protein phosphorylation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0048869//cellular developmental process;GO:0006914//autophagy gi|6754954|ref|NP_035148.1|/0/sequestosome-1 isoform 1 [Mus musculus] 17085 2169 0.413333333 0.616666667 0.57718515 Up 0.240973711 Ly9 lymphocyte antigen 9 K06570|1|0.0|1221|mmu:17085|lymphocyte antigen 9 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0022610;GO:0022610;GO:0022610 gi|485464599|ref|NP_001264897.1|/0/T-lymphocyte surface antigen Ly-9 isoform 2 [Mus musculus] 19207 5114.11 0.59 0.393333333 -0.584962501 Down 0.240973711 Ptch2 patched 2 K11101|1|0.0|2072|mmu:19207|patched 2 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity GO:0008544//epidermis development;GO:0042303//molting cycle;GO:0008544//epidermis development;GO:0042303//molting cycle "gi|148698625|gb|EDL30572.1|/0/patched homolog 2, isoform CRA_b [Mus musculus]" 224530 1991 16.91 18.15 0.102092888 Up 0.240945504 Acat3 acetyl-Coenzyme A acetyltransferase 3 K00626|1|0.0|739|mmu:110460|acetyl-CoA C-acetyltransferase [EC:2.3.1.9] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0003988//acetyl-CoA C-acyltransferase activity GO:0007417//central nervous system development;GO:0044248;GO:0070542//response to fatty acid;GO:0007584//response to nutrient gi|110625948|ref|NP_694791.2|/0/acetyl-Coenzyme A acetyltransferase 3 [Mus musculus] 66887 2936 32.74 34.93333333 0.093549989 Up 0.240936101 Lonp2 "lon peptidase 2, peroxisomal" K01338|1|0.0|795|mmu:66887|ATP-dependent Lon protease [EC:3.4.21.53] - - - "gi|13385298|ref|NP_080103.1|/0/lon protease homolog 2, peroxisomal isoform 1 [Mus musculus]" 17859 5036.12 12.54666667 11.6 -0.113179322 Down 0.240870285 Mxi1 "MAX interactor 1, dimerization protein" K09114|1|3e-96|356|mmu:17859|MAX dimerization protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding "GO:0042992//negative regulation of transcription factor import into nucleus;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|114520596|ref|NP_001008542.2|/1.78789e-127/max-interacting protein 1 isoform b [Mus musculus] 11980 8131 4.776666667 4.29 -0.155026556 Down 0.240832675 Atp8a1 "ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1" K14802|1|0.0|2281|mmu:11980|phospholipid-transporting ATPase [EC:3.6.3.1] GO:0031224//intrinsic component of membrane;GO:0030667//secretory granule membrane;GO:0031224//intrinsic component of membrane;GO:0030667//secretory granule membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle GO:0032550;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0003824//catalytic activity;GO:0032550;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0003824//catalytic activity;GO:0032550;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0003824//catalytic activity GO:0044763;GO:0006811//ion transport;GO:0015914//phospholipid transport;GO:0044763;GO:0006811//ion transport;GO:0015914//phospholipid transport;GO:0006811//ion transport;GO:0006869//lipid transport gi|60360628|dbj|BAD90541.1|/0/mKIAA4233 protein [Mus musculus] 20166 2302.94 4.236666667 4.723333333 0.156875728 Up 0.240832675 Rtkn rhotekin K18621|1|3e-06|57.4|cin:100184096|actin-binding protein anillin GO:0044464;GO:0044464;GO:0044464 GO:0008289//lipid binding;GO:0004857//enzyme inhibitor activity;GO:0017048//Rho GTPase binding;GO:0032550;GO:0008289//lipid binding;GO:0004857//enzyme inhibitor activity;GO:0017048//Rho GTPase binding;GO:0032550;GO:0008289//lipid binding;GO:0004857//enzyme inhibitor activity;GO:0017048//Rho GTPase binding;GO:0032550 GO:0012501//programmed cell death;GO:0044092//negative regulation of molecular function;GO:0007265//Ras protein signal transduction;GO:0012501//programmed cell death;GO:0044092//negative regulation of molecular function;GO:0007265//Ras protein signal transduction;GO:0012501//programmed cell death;GO:0044092//negative regulation of molecular function;GO:0007265//Ras protein signal transduction gi|209977095|ref|NP_001129699.1|/0/rhotekin isoform a [Mus musculus] 27368 4407 3.026666667 2.636666667 -0.199014603 Down 0.240766858 Tbl2 transducin (beta)-like 2 K09113|1|2e-149|533|fch:102054276|MAX-like protein X;K13917|4|5e-69|266|ame:414001|mRNA-capping enzyme [EC:2.7.7.50 3.6.1.-];K16482|5|5e-13|80.1|ola:101161307|centriolar protein POC1 - - - "gi|148687432|gb|EDL19379.1|/0/transducin (beta)-like 2, isoform CRA_a, partial [Mus musculus]" 76222 1457 1.45 1.173333333 -0.305439972 Down 0.240766858 Magef1 "melanoma antigen family F, 1" K19482|1|4e-09|65.5|tup:102494777|necdin - - - - 13190 2279 3.093333333 2.7 -0.196202897 Down 0.240766858 Dct dopachrome tautomerase K01827|1|0.0|1014|mmu:13190|dopachrome tautomerase [EC:5.3.3.12] GO:0031224//intrinsic component of membrane;GO:0048770 "GO:0043169//cation binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds" GO:0006570//tyrosine metabolic process;GO:0030154//cell differentiation;GO:0006582//melanin metabolic process;GO:0021869//forebrain ventricular zone progenitor cell division gi|171904008|gb|ACB56630.1|/0/dopachrome tautomerase [Mus musculus] 74925 740 0.28 0.126666667 -1.144389909 Down 0.240757456 4930479D17Rik RIKEN cDNA 4930479D17 gene - - - - - 224671 6857 3.67 3.243333333 -0.178302759 Down 0.240644627 Btbd9 BTB (POZ) domain containing 9 K10481|1|0.0|1196|mmu:224671|BTB/POZ domain-containing protein 9 - - GO:0022610;GO:0007600//sensory perception;GO:0007613//memory;GO:0007626//locomotory behavior;GO:0022410//circadian sleep/wake cycle process;GO:0042430//indole-containing compound metabolic process;GO:0048871//multicellular organismal homeostasis;GO:0030100//regulation of endocytosis;GO:0022610;GO:0007600//sensory perception;GO:0007613//memory;GO:0007626//locomotory behavior;GO:0022410//circadian sleep/wake cycle process;GO:0042430//indole-containing compound metabolic process;GO:0048871//multicellular organismal homeostasis;GO:0030100//regulation of endocytosis gi|27819604|ref|NP_766206.1|/0/BTB/POZ domain-containing protein 9 [Mus musculus] 235567 7697 3.663333333 3.236666667 -0.178648186 Down 0.240644627 Dnajc13 DnaJ heat shock protein family (Hsp40) member C13 K09533|1|0.0|4270|mmu:235567|DnaJ homolog subfamily C member 13 - - - - 13591 5246.05 3.736666667 3.303333333 -0.177829316 Down 0.240644627 Ebf1 early B cell factor 1 K09103|1|0.0|1119|mmu:13591|early B-cell factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0019904//protein domain specific binding;GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0019904//protein domain specific binding;GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0019904//protein domain specific binding "GO:0006351//transcription, DNA-templated;GO:0032502//developmental process;GO:0006351//transcription, DNA-templated;GO:0032502//developmental process;GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|595582326|ref|NP_001277639.1|/0/transcription factor COE1 isoform 3 [Mus musculus] 109169 1378 3.646666667 3.216666667 -0.181011891 Down 0.240644627 Igip IgA inducing protein - - - - gi|664713685|ref|XP_008513810.1|/2.09044e-30/PREDICTED: IgA-inducing protein homolog [Equus przewalskii] 100043636 1408 0.556666667 0.776666667 0.480481852 Up 0.240588213 AI662270 expressed sequence AI662270 - - - - - 77442 884 0.776666667 0.556666667 -0.480481852 Down 0.240588213 9530020I12Rik RIKEN cDNA 9530020I12 gene - - - - - 22340 1269.31 318.6 301.85 -0.077914466 Down 0.240550604 Vegfb vascular endothelial growth factor B K16858|1|2e-97|358|mmu:22340|vascular endothelial growth factor B GO:0044464;GO:0044421;GO:0044464;GO:0044421 GO:0005172//vascular endothelial growth factor receptor binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0005539//glycosaminoglycan binding;GO:0005172//vascular endothelial growth factor receptor binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0005539//glycosaminoglycan binding GO:0001934//positive regulation of protein phosphorylation;GO:0006941//striated muscle contraction;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0050927//positive regulation of positive chemotaxis;GO:0001935//endothelial cell proliferation;GO:0045766//positive regulation of angiogenesis;GO:0002551//mast cell chemotaxis;GO:0006486//protein glycosylation;GO:0048869//cellular developmental process;GO:0043410//positive regulation of MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0006941//striated muscle contraction;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0050927//positive regulation of positive chemotaxis;GO:0001935//endothelial cell proliferation;GO:0045766//positive regulation of angiogenesis;GO:0002551//mast cell chemotaxis;GO:0006486//protein glycosylation;GO:0048869//cellular developmental process;GO:0043410//positive regulation of MAPK cascade;GO:0043114//regulation of vascular permeability gi|6755969|ref|NP_035827.1|/2.01027e-96/vascular endothelial growth factor B isoform Vegf-b186 precursor [Mus musculus] 320705 2256 0.196666667 0.366666667 0.898716664 Up 0.240484787 Bend6 BEN domain containing 6 - - - - - 238161 10263 9.48 8.72 -0.120558924 Down 0.240484787 Akap6 A kinase (PRKA) anchor protein 6 K16523|1|0.0|4076|mmu:238161|A-kinase anchor protein 6 GO:0031965//nuclear membrane;GO:0034703//cation channel complex;GO:0005783//endoplasmic reticulum;GO:0044459 "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0051018//protein kinase A binding" GO:0032512;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0006171//cAMP biosynthetic process gi|116517311|ref|NP_932779.2|/0/A-kinase anchor protein 6 [Mus musculus] 114774 1828 1.356666667 1.083333333 -0.324589076 Down 0.24045658 Pawr "PRKC, apoptosis, WT1, regulator" K06270|1|6e-07|58.5|lcm:102356119|protein phosphatase 1 regulatory subunit 12A GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton GO:0030275//LRR domain binding;GO:0003712//transcription cofactor activity;GO:0008092//cytoskeletal protein binding GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0030888//regulation of B cell proliferation;GO:0007015//actin filament organization;GO:0050852//T cell receptor signaling pathway;GO:0012502//induction of programmed cell death;GO:0010560//positive regulation of glycoprotein biosynthetic process;GO:0032623//interleukin-2 production;GO:0042098//T cell proliferation "gi|148689758|gb|EDL21705.1|/1.04419e-163/mCG16868, isoform CRA_b, partial [Mus musculus]" 108755 1344 13.37333333 12.43 -0.105532809 Down 0.240447177 Lyrm2 LYR motif containing 2 - GO:0043231//intracellular membrane-bounded organelle - - gi|30425062|ref|NP_780573.1|/2.62814e-38/LYR motif-containing protein 2 [Mus musculus] 245867 3568 11.79666667 12.73666667 0.110608496 Up 0.240447177 Pcmtd2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 K00573|1|1e-14|85.5|smm:Smp_058140.3|protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] GO:0044424;GO:0044424 GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity GO:0036211//protein modification process;GO:0036211//protein modification process gi|49387472|dbj|BAD24965.1|/0/mKIAA3003 protein [Mus musculus] 72999 2558.78 18.39333333 17.17 -0.099292917 Down 0.24041897 Insig2 insulin induced gene 2 - GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0006984//ER-nucleus signaling pathway;GO:0097094//craniofacial suture morphogenesis;GO:0006639//acylglycerol metabolic process;GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0043434//response to peptide hormone;GO:0042471//ear morphogenesis;GO:0006950//response to stress;GO:0033993//response to lipid;GO:0006984//ER-nucleus signaling pathway;GO:0097094//craniofacial suture morphogenesis;GO:0006639//acylglycerol metabolic process;GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0043434//response to peptide hormone;GO:0042471//ear morphogenesis;GO:0006950//response to stress;GO:0033993//response to lipid;GO:0006984//ER-nucleus signaling pathway;GO:0097094//craniofacial suture morphogenesis;GO:0006639//acylglycerol metabolic process;GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0043434//response to peptide hormone;GO:0042471//ear morphogenesis;GO:0006950//response to stress;GO:0033993//response to lipid;GO:0006984//ER-nucleus signaling pathway;GO:0097094//craniofacial suture morphogenesis;GO:0006639//acylglycerol metabolic process;GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0043434//response to peptide hormone;GO:0042471//ear morphogenesis;GO:0006950//response to stress;GO:0033993//response to lipid "gi|148707842|gb|EDL39789.1|/7.06756e-129/insulin induced gene 2, isoform CRA_a, partial [Mus musculus]" 110829 4400.22 18.74666667 17.53 -0.096808098 Down 0.24041897 Lims1 LIM and senescent cell antigen-like domains 1 K05760|1|3e-37|160|api:100168156|paxillin GO:0032991//macromolecular complex;GO:0005924//cell-substrate adherens junction;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0005924//cell-substrate adherens junction;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding "GO:0051259//protein oligomerization;GO:0007229//integrin-mediated signaling pathway;GO:0034330;GO:0006351//transcription, DNA-templated;GO:0009792//embryo development ending in birth or egg hatching;GO:0031589//cell-substrate adhesion;GO:0071363//cellular response to growth factor stimulus;GO:0051259//protein oligomerization;GO:0007229//integrin-mediated signaling pathway;GO:0034330;GO:0006351//transcription, DNA-templated;GO:0009792//embryo development ending in birth or egg hatching;GO:0031589//cell-substrate adhesion;GO:0051259//protein oligomerization;GO:0007229//integrin-mediated signaling pathway;GO:0034330;GO:0006351//transcription, DNA-templated;GO:0009792//embryo development ending in birth or egg hatching;GO:0031589//cell-substrate adhesion" gi|589954590|ref|XP_006989922.1|/0/PREDICTED: LIM and senescent cell antigen-like-containing domain protein 3 isoform X4 [Peromyscus maniculatus bairdii] 67544 4779.83 5.676666667 6.253333333 0.139581393 Up 0.240353154 Fam120b "family with sequence similarity 120, member B" K06251|1|1e-09|69.3|cmk:103180587|vitronectin - - "GO:0006351//transcription, DNA-templated;GO:0048869//cellular developmental process;GO:0006351//transcription, DNA-templated;GO:0048869//cellular developmental process" gi|51988904|ref|NP_077165.2|/0/constitutive coactivator of peroxisome proliferator-activated receptor gamma [Mus musculus] 22697 2304.02 7.433333333 6.78 -0.132724031 Down 0.240249727 Zscan21 zinc finger and SCAN domain containing 21 K09230|1|0.0|1117|mmu:22697|SCAN domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0048869//cellular developmental process;GO:0044764;GO:0007292//female gamete generation;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0048869//cellular developmental process;GO:0044764;GO:0007292//female gamete generation;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0048869//cellular developmental process;GO:0044764;GO:0007292//female gamete generation;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0048869//cellular developmental process;GO:0044764;GO:0007292//female gamete generation;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated" "gi|148687272|gb|EDL19219.1|/0/zinc finger proliferation 1, isoform CRA_b, partial [Mus musculus]" 53607 1369.84 33.21666667 35.32333333 0.088714187 Up 0.240136899 Snrpa small nuclear ribonucleoprotein polypeptide A K11091|1|1e-97|359|mmu:53607|U1 small nuclear ribonucleoprotein A GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen;GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen;GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0000377;GO:0000377;GO:0000377 gi|114052106|ref|NP_056597.3|/9.81456e-97/U1 small nuclear ribonucleoprotein A [Mus musculus] 59126 3168 1.003333333 1.266666667 0.336235932 Up 0.240136899 Nek6 NIMA (never in mitosis gene a)-related expressed kinase 6 K08857|1|0.0|645|mmu:59126|NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0008092//cytoskeletal protein binding;GO:0032550;GO:0004672//protein kinase activity;GO:0019900//kinase binding;GO:0046872//metal ion binding;GO:0060089;GO:0008092//cytoskeletal protein binding;GO:0032550;GO:0004672//protein kinase activity;GO:0019900//kinase binding;GO:0046872//metal ion binding;GO:0060089 GO:0012501//programmed cell death;GO:0006468//protein phosphorylation;GO:0007088//regulation of mitotic nuclear division;GO:0000077//DNA damage checkpoint;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0012501//programmed cell death;GO:0006468//protein phosphorylation;GO:0007088//regulation of mitotic nuclear division;GO:0000077//DNA damage checkpoint;GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|568914047|ref|XP_006498272.1|/0/PREDICTED: serine/threonine-protein kinase Nek6 isoform X2 [Mus musculus] 22761 3393 17.55666667 16.34666667 -0.10302248 Down 0.240080484 Zfpm1 "zinc finger protein, multitype 1" K17441|1|0.0|1540|mmu:22761|zinc finger protein ZFPM1 GO:0031981//nuclear lumen;GO:0043234//protein complex "GO:0046872//metal ion binding;GO:0003712//transcription cofactor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0003676//nucleic acid binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding" GO:0042095//interferon-gamma biosynthetic process;GO:0030219//megakaryocyte differentiation;GO:0045646//regulation of erythrocyte differentiation;GO:0042036//negative regulation of cytokine biosynthetic process;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0003171//atrioventricular valve development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0003281//ventricular septum development;GO:0003209//cardiac atrium morphogenesis;GO:0043393//regulation of protein binding;GO:0003183//mitral valve morphogenesis;GO:0003186//tricuspid valve morphogenesis gi|6677633|ref|NP_033595.1|/0/zinc finger protein ZFPM1 [Mus musculus] 74648 1546 2.276666667 1.936666667 -0.233347415 Down 0.240042875 S100pbp S100P binding protein - - GO:0005515//protein binding - gi|62899073|ref|NP_083312.1|/0/S100P-binding protein [Mus musculus] 12508 2802 2.033333333 2.376666667 0.225092834 Up 0.240042875 Cd53 CD53 antigen K06489|1|5e-124|448|mmu:12508|CD53 antigen GO:0044459;GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0007154//cell communication;GO:0040007//growth "gi|148669936|gb|EDL01883.1|/7.9274e-132/CD53 antigen, isoform CRA_a, partial [Mus musculus]" 20935 2593 3.55 3.996666667 0.170978228 Up 0.240033472 Surf6 surfeit gene 6 K09142|1|9e-37|158|xma:102227156|uncharacterized protein GO:0005654//nucleoplasm GO:0003676//nucleic acid binding GO:0042254//ribosome biogenesis gi|6678185|ref|NP_033324.1|/2.84317e-136/surfeit locus protein 6 [Mus musculus] 66323 954 0.426666667 0.25 -0.77118131 Down 0.240014668 1700001K19Rik RIKEN cDNA 1700001K19 gene - - - - gi|568980227|ref|XP_006516211.1|/3.48733e-115/PREDICTED: uncharacterized protein LOC66323 isoform X3 [Mus musculus] 230779 1892 0.26 0.443333333 0.769880217 Up 0.240014668 Serinc2 serine incorporator 2 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0015179//L-amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity GO:0006575//cellular modified amino acid metabolic process;GO:0006643//membrane lipid metabolic process;GO:0043085//positive regulation of catalytic activity;GO:0015807//L-amino acid transport;GO:0006575//cellular modified amino acid metabolic process;GO:0006643//membrane lipid metabolic process;GO:0043085//positive regulation of catalytic activity;GO:0015807//L-amino acid transport gi|26344730|dbj|BAC36014.1|/0/unnamed protein product [Mus musculus] 17938 6423.96 253.5133333 267.33 0.076560121 Up 0.239986461 Naca nascent polypeptide-associated complex alpha polypeptide K03626|1|7e-88|326|cmy:102942765|nascent polypeptide-associated complex subunit alpha GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0008134//transcription factor binding;GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0008134//transcription factor binding "GO:0061383//trabecula morphogenesis;GO:0048641//regulation of skeletal muscle tissue development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042246//tissue regeneration;GO:0048630//skeletal muscle tissue growth;GO:0008284//positive regulation of cell proliferation;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0003205//cardiac chamber development;GO:0045184//establishment of protein localization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045184//establishment of protein localization;GO:0006351//transcription, DNA-templated;GO:0061383//trabecula morphogenesis;GO:0048641//regulation of skeletal muscle tissue development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042246//tissue regeneration;GO:0048630//skeletal muscle tissue growth;GO:0008284//positive regulation of cell proliferation;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0003205//cardiac chamber development;GO:0045184//establishment of protein localization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter" gi|927154499|ref|XP_013917318.1|/1.57925e-87/PREDICTED: nascent polypeptide-associated complex subunit alpha [Thamnophis sirtalis] 57752 4605.4 259.0966667 245.3033333 -0.078923617 Down 0.239977058 Tacc2 "transforming, acidic coiled-coil containing protein 2" K14282|1|0.0|2037|mmu:57752|transforming acidic coiled-coil-containing protein 2 GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle GO:0051427//hormone receptor binding;GO:0051427//hormone receptor binding GO:0007051//spindle organization;GO:0021543//pallium development;GO:0021846//cell proliferation in forebrain;GO:0007051//spindle organization;GO:0021543//pallium development;GO:0021846//cell proliferation in forebrain gi|52486915|ref|NP_996738.2|/0/transforming acidic coiled-coil-containing protein 2 isoform a [Mus musculus] 11813 584 0.333333333 0.526666667 0.659924558 Up 0.239967656 Apoc2 apolipoprotein C-II - GO:0034385;GO:0034364//high-density lipoprotein particle;GO:0034385;GO:0034364//high-density lipoprotein particle GO:0042802//identical protein binding;GO:0019899//enzyme binding;GO:0004857//enzyme inhibitor activity;GO:0060229//lipase activator activity;GO:0042802//identical protein binding;GO:0019899//enzyme binding;GO:0004857//enzyme inhibitor activity;GO:0060229//lipase activator activity GO:0051004;GO:0006898//receptor-mediated endocytosis;GO:0055090//acylglycerol homeostasis;GO:0015914//phospholipid transport;GO:0015031//protein transport;GO:0010915;GO:0006633//fatty acid biosynthetic process;GO:0009395//phospholipid catabolic process;GO:0044092//negative regulation of molecular function;GO:0044093;GO:0030301//cholesterol transport;GO:0071830;GO:0010896//regulation of triglyceride catabolic process;GO:0010517//regulation of phospholipase activity;GO:0051004;GO:0006898//receptor-mediated endocytosis;GO:0055090//acylglycerol homeostasis;GO:0015914//phospholipid transport;GO:0015031//protein transport;GO:0010915;GO:0006633//fatty acid biosynthetic process;GO:0009395//phospholipid catabolic process;GO:0044092//negative regulation of molecular function;GO:0044093;GO:0030301//cholesterol transport;GO:0071830;GO:0010896//regulation of triglyceride catabolic process;GO:0010517//regulation of phospholipase activity gi|485050543|ref|NP_001264873.1|/1.56075e-46/apolipoprotein C-II precursor [Mus musculus] 66446 1037 12.5 11.57 -0.11153923 Down 0.239958253 Exosc7 exosome component 7 K12589|1|7e-165|582|mmu:66446|exosome complex component RRP42 GO:0043231//intracellular membrane-bounded organelle GO:0004527//exonuclease activity;GO:0003676//nucleic acid binding GO:0042254//ribosome biogenesis gi|124487127|ref|NP_001074657.1|/6.10344e-164/exosome complex exonuclease RRP42 [Mus musculus] 69082 1963 12.67666667 11.75 -0.109514681 Down 0.239958253 Zc3h15 zinc finger CCCH-type containing 15 - GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0007166//cell surface receptor signaling pathway gi|34368584|ref|NP_081210.2|/0/zinc finger CCCH domain-containing protein 15 [Mus musculus] 223672 1475 0.573333333 0.793333333 0.468553009 Up 0.239948851 Apol9a apolipoprotein L 9a K14480|1|7e-147|523|mmu:223672|apolipoprotein L - - - "gi|148697701|gb|EDL29648.1|/2.98567e-163/RIKEN cDNA 2310016F22, isoform CRA_c, partial [Mus musculus]" 53328 1890 9.49 8.74 -0.118774808 Down 0.239930046 Pgrmc1 progesterone receptor membrane component 1 K17278|1|9e-102|373|mmu:53328|membrane-associated progesterone receptor component - - - - 67834 2418 242.3966667 229.01 -0.081959263 Down 0.239920644 Idh3a isocitrate dehydrogenase 3 (NAD+) alpha K00030|1|0.0|736|cge:100754480|isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] GO:0030062//mitochondrial tricarboxylic acid cycle enzyme complex GO:0046872//metal ion binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding GO:0043648//dicarboxylic acid metabolic process;GO:0072350//tricarboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0019674//NAD metabolic process "gi|148693873|gb|EDL25820.1|/0/isocitrate dehydrogenase 3 (NAD+) alpha, isoform CRA_c, partial [Mus musculus]" 69893 2876 5.426666667 4.903333333 -0.146303453 Down 0.239883034 Coa7 cytochrome c oxidase assembly factor 7 K18180|1|1e-136|489|mmu:69893|cytochrome c oxidase assembly factor 7 - - - gi|28076933|ref|NP_081526.1|/1.21968e-135/cytochrome c oxidase assembly factor 7 [Mus musculus] 230738 2805 4.823333333 5.343333333 0.147709504 Up 0.239883034 Zc3h12a zinc finger CCCH type containing 12A K18668|1|0.0|1055|mmu:230738|ribonuclease ZC3H12 [EC:3.1.-.-] GO:0031981//nuclear lumen;GO:0016020//membrane GO:0043169//cation binding;GO:0004518//nuclease activity GO:0032496//response to lipopolysaccharide;GO:0012501//programmed cell death;GO:0001818//negative regulation of cytokine production;GO:0045444//fat cell differentiation;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0006809//nitric oxide biosynthetic process;GO:0006914//autophagy;GO:0072593//reactive oxygen species metabolic process;GO:0010883//regulation of lipid storage "gi|148698376|gb|EDL30323.1|/0/zinc finger CCCH type containing 12A, partial [Mus musculus]" 76628 2215 0.893333333 1.143333333 0.355975576 Up 0.239854827 1700112J16Rik RIKEN cDNA 1700112J16 gene - - - - - 20463 1101.19 228.5433333 241.3966667 0.078938019 Up 0.239807815 Cox7a2l cytochrome c oxidase subunit VIIa polypeptide 2-like K02270|1|2e-58|228|mmu:20463|cytochrome c oxidase subunit 7a GO:0005743//mitochondrial inner membrane;GO:0005743//mitochondrial inner membrane - GO:0006818//hydrogen transport;GO:0006811//ion transport;GO:0044710;GO:0006818//hydrogen transport;GO:0006811//ion transport;GO:0044710 "gi|148706604|gb|EDL38551.1|/6.48305e-76/cytochrome c oxidase subunit VIIa polypeptide 2-like, isoform CRA_d [Mus musculus]" 338360 2623 0.766666667 1.006666667 0.392914688 Up 0.23978901 B430212C06Rik RIKEN cDNA B430212C06 gene - - - - "gi|148677705|gb|EDL09652.1|/2.51305e-39/mCG10509, isoform CRA_b [Mus musculus]" 212632 5432.34 2.73 2.356666667 -0.212153237 Down 0.239760803 Iffo2 intermediate filament family orphan 2 K07606|1|8e-17|93.2|clv:102087530|vimentin - - - gi|326937467|ref|NP_001192102.1|/0/intermediate filament family orphan 2 isoform 1 [Mus musculus] 239217 6076 2.67 2.303333333 -0.213116532 Down 0.239760803 Kctd12 potassium channel tetramerisation domain containing 12 - GO:0043234//protein complex;GO:0097060//synaptic membrane - GO:0007186//G-protein coupled receptor signaling pathway;GO:0051259//protein oligomerization gi|123701966|ref|NP_808383.3|/1.61678e-159/BTB/POZ domain-containing protein KCTD12 [Mus musculus] 320624 2663 0.216666667 0.073333333 -1.562936194 Down 0.239732596 4930474G06Rik RIKEN cDNA 4930474G06 gene K11290|1|6e-13|51.6|rno:317165|template-activating factor I - - - "gi|68062212|ref|XP_673109.1|/2.84821e-14/hypothetical protein [Plasmodium berghei strain ANKA], partial [Plasmodium berghei ANKA]" 70415 3335 0.073333333 0.213333333 1.540568381 Up 0.239732596 Stk26 serine/threonine kinase 26 K08838|1|0.0|743|mmu:70415|serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1] - - - - 269252 7021 2.16 2.51 0.216656052 Up 0.239676182 Gtf3c4 "general transcription factor IIIC, polypeptide 4" K11310|1|0.0|1407|mmu:269252|general transcription factor 3C polypeptide 4 [EC:2.3.1.48] GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0003676//nucleic acid binding;GO:0030234//enzyme regulator activity;GO:0008080//N-acetyltransferase activity;GO:0003676//nucleic acid binding;GO:0030234//enzyme regulator activity;GO:0008080//N-acetyltransferase activity GO:0006383//transcription from RNA polymerase III promoter;GO:0044093;GO:0016570//histone modification;GO:0006383//transcription from RNA polymerase III promoter;GO:0044093;GO:0016570//histone modification gi|260436918|ref|NP_766565.2|/0/general transcription factor 3C polypeptide 4 isoform 1 [Mus musculus] 319845 3382 2.503333333 2.156666667 -0.215047196 Down 0.239676182 Bbs9 Bardet-Biedl syndrome 9 (human) K19398|1|0.0|1674|mmu:319845|Bardet-Biedl syndrome 9 protein GO:0016020//membrane;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - - "gi|148693332|gb|EDL25279.1|/0/RIKEN cDNA E130103I17, isoform CRA_b, partial [Mus musculus]" 224585 3809 0.68 0.473333333 -0.522678222 Down 0.239610365 Zfp160 zinc finger protein 160 K09228|1|0.0|1363|mmu:224585|KRAB domain-containing zinc finger protein - - - gi|162135948|ref|NP_663458.2|/0/zinc finger protein 160 [Mus musculus] 24057 1633 0.473333333 0.68 0.522678222 Up 0.239610365 Sh3yl1 Sh3 domain YSC-like 1 K20523|1|0.0|644|mmu:24057|SH3 domain-containing YSC84-like protein 1 GO:0001726//ruffle;GO:0001726//ruffle;GO:0001726//ruffle GO:0005543//phospholipid binding;GO:0019899//enzyme binding;GO:0005543//phospholipid binding;GO:0019899//enzyme binding;GO:0005543//phospholipid binding;GO:0019899//enzyme binding GO:0060491//regulation of cell projection assembly;GO:0046474//glycerophospholipid biosynthetic process;GO:0060491//regulation of cell projection assembly;GO:0046474//glycerophospholipid biosynthetic process;GO:0060491//regulation of cell projection assembly;GO:0046474//glycerophospholipid biosynthetic process gi|7305487|ref|NP_038737.1|/0/SH3 domain-containing YSC84-like protein 1 isoform 1 [Mus musculus] 227613 1600 203.5833333 215.5833333 0.08262619 Up 0.23959156 Tubb4b "tubulin, beta 4B class IVB" K07375|1|0.0|831|lcm:102348335|tubulin beta GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0042287//MHC protein binding;GO:0005198//structural molecule activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0006458//'de novo' protein folding;GO:0044772//mitotic cell cycle phase transition;GO:0043623//cellular protein complex assembly;GO:0009154//purine ribonucleotide catabolic process;GO:0001909//leukocyte mediated cytotoxicity gi|634865305|ref|XP_007945164.1|/0/PREDICTED: tubulin beta-4B chain isoform X1 [Orycteropus afer afer] 66961 3220.65 215.5 203.51 -0.082588182 Down 0.23959156 Neat1 nuclear paraspeckle assembly transcript 1 (non-protein coding) - - - - - 114332 2607 15.80333333 16.99333333 0.10473998 Up 0.239553951 Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 K19012|1|3e-160|568|mmu:114332|lymphatic vessel endothelial hyaluronan receptor 1 GO:0031224//intrinsic component of membrane;GO:0044464 GO:0005539//glycosaminoglycan binding GO:0051234//establishment of localization;GO:0022610;GO:0007154//cell communication;GO:0006026 gi|31560771|ref|NP_444477.2|/2.40698e-159/lymphatic vessel endothelial hyaluronic acid receptor 1 precursor [Mus musculus] 16179 3809.44 32.85333333 34.90666667 0.087462841 Up 0.239506939 Irak1 interleukin-1 receptor-associated kinase 1 K04730|1|0.0|1186|mmu:16179|interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0004672//protein kinase activity;GO:0005126//cytokine receptor binding;GO:0032550;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0004672//protein kinase activity;GO:0005126//cytokine receptor binding;GO:0032550;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0004672//protein kinase activity;GO:0005126//cytokine receptor binding;GO:0032550;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0004672//protein kinase activity;GO:0005126//cytokine receptor binding;GO:0032550;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0004672//protein kinase activity;GO:0005126//cytokine receptor binding;GO:0032550;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity GO:0006461//protein complex assembly;GO:0008284//positive regulation of cell proliferation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032147//activation of protein kinase activity;GO:0043406//positive regulation of MAP kinase activity;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0019221//cytokine-mediated signaling pathway;GO:0001666//response to hypoxia;GO:0051403//stress-activated MAPK cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0002224//toll-like receptor signaling pathway;GO:0010874//regulation of cholesterol efflux;GO:0032496//response to lipopolysaccharide;GO:0006461//protein complex assembly;GO:0008284//positive regulation of cell proliferation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032147//activation of protein kinase activity;GO:0043406//positive regulation of MAP kinase activity;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0019221//cytokine-mediated signaling pathway;GO:0001666//response to hypoxia;GO:0051403//stress-activated MAPK cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0002224//toll-like receptor signaling pathway;GO:0010874//regulation of cholesterol efflux;GO:0032496//response to lipopolysaccharide;GO:0006461//protein complex assembly;GO:0008284//positive regulation of cell proliferation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032147//activation of protein kinase activity;GO:0043406//positive regulation of MAP kinase activity;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0019221//cytokine-mediated signaling pathway;GO:0001666//response to hypoxia;GO:0051403//stress-activated MAPK cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0002224//toll-like receptor signaling pathway;GO:0010874//regulation of cholesterol efflux;GO:0032496//response to lipopolysaccharide;GO:0006461//protein complex assembly;GO:0008284//positive regulation of cell proliferation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032147//activation of protein kinase activity;GO:0043406//positive regulation of MAP kinase activity;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0019221//cytokine-mediated signaling pathway;GO:0001666//response to hypoxia;GO:0051403//stress-activated MAPK cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0002224//toll-like receptor signaling pathway;GO:0010874//regulation of cholesterol efflux;GO:0032496//response to lipopolysaccharide;GO:0006461//protein complex assembly;GO:0008284//positive regulation of cell proliferation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032147//activation of protein kinase activity;GO:0043406//positive regulation of MAP kinase activity;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0019221//cytokine-mediated signaling pathway;GO:0001666//response to hypoxia;GO:0051403//stress-activated MAPK cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0002224//toll-like receptor signaling pathway;GO:0010874//regulation of cholesterol efflux;GO:0032496//response to lipopolysaccharide gi|295789115|ref|NP_001171447.1|/0/interleukin-1 receptor-associated kinase 1 isoform 2 [Mus musculus] 215690 12767 4.533333333 4.05 -0.162650338 Down 0.239412915 Nav1 neuron navigator 1 K16776|1|0.0|3153|mmu:215690|neuron navigator 1 GO:0005856//cytoskeleton GO:0016462//pyrophosphatase activity;GO:0032550 GO:0016477//cell migration;GO:0000226//microtubule cytoskeleton organization gi|568908639|ref|XP_006529442.1|/0/PREDICTED: neuron navigator 1 isoform X10 [Mus musculus] 23887 4137 4 4.48 0.163498732 Up 0.239412915 Ggt5 gamma-glutamyltransferase 5 K18592|1|0.0|1058|mmu:23887|gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14] GO:0031224//intrinsic component of membrane "GO:0016755//transferase activity, transferring amino-acyl groups" GO:0006952//defense response;GO:0009719;GO:0006749//glutathione metabolic process;GO:0006636//unsaturated fatty acid biosynthetic process gi|31542891|ref|NP_035950.2|/0/gamma-glutamyltransferase 5 [Mus musculus] 22288 12382 4.506666667 4.023333333 -0.163669476 Down 0.239412915 Utrn utrophin K10366|1|0.0|2786|shr:100921237|dystrophin - - - gi|110431378|ref|NP_035812.3|/0/utrophin [Mus musculus] 75430 843 6.266666667 5.7 -0.136736337 Down 0.239365903 Anapc15 anaphase prompoting complex C subunit 15 - - - GO:0000278//mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0000278//mitotic cell cycle gi|674088695|ref|XP_008852282.1|/1.86479e-45/PREDICTED: anaphase-promoting complex subunit 15 isoform X4 [Nannospalax galili] 72515 3450 6.183333333 5.61 -0.14038401 Down 0.239365903 Wdr43 WD repeat domain 43 K14546|1|0.0|1161|mmu:72515|U3 small nucleolar RNA-associated protein 5 - - - "gi|148706445|gb|EDL38392.1|/0/mCG5393, partial [Mus musculus]" 240168 4728 6.046666667 5.473333333 -0.143720329 Down 0.239365903 Rasgrp3 "RAS, guanyl releasing protein 3" K12362|1|0.0|1323|mmu:240168|RAS guanyl-releasing protein 3 GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0031267//small GTPase binding;GO:0043169//cation binding;GO:0031267//small GTPase binding;GO:0043169//cation binding - gi|50510667|dbj|BAD32319.1|/0/mKIAA0846 protein [Mus musculus] 227485 3054 0.286666667 0.133333333 -1.10433666 Down 0.239337696 Cdh19 "cadherin 19, type 2" "K06806|1|0.0|1434|mmu:227485|cadherin 19, type 2" GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|124487065|ref|NP_001074855.1|/0/cadherin-19 precursor [Mus musculus] 103729 1500 0.7 0.933333333 0.415037499 Up 0.239318891 AI450353 expressed sequence AI450353 - - - - - 383678 732 0.213333333 0.076666667 -1.476438044 Down 0.239206063 Obp2b odorant binding protein 2B K01830|1|1e-11|72.4|shr:100913465|prostaglandin-H2 D-isomerase [EC:5.3.99.2] - - - gi|568913948|ref|XP_006498225.1|/1.16713e-97/PREDICTED: odorant-binding protein 2a isoform X1 [Mus musculus] 19245 3602.86 185.9533333 196.8833333 0.082400379 Up 0.23919666 Ptp4a3 protein tyrosine phosphatase 4a3 K18041|1|2e-97|360|rno:362930|protein tyrosine phosphatase type IVA [EC:3.1.3.48] GO:0005768//endosome;GO:0016020//membrane;GO:0005768//endosome;GO:0016020//membrane;GO:0005768//endosome;GO:0016020//membrane;GO:0005768//endosome;GO:0016020//membrane GO:0004725//protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity GO:0006470//protein dephosphorylation;GO:0006470//protein dephosphorylation;GO:0006470//protein dephosphorylation;GO:0006470//protein dephosphorylation gi|537237916|gb|ERE86188.1|/3.19403e-102/protein tyrosine phosphatase type IVA 3-like protein [Cricetulus griseus] 227154 2338 31.97333333 33.99333333 0.088382679 Up 0.239130844 Stradb STE20-related kinase adaptor beta K17532|1|0.0|806|mmu:227154|STE20-related kinase adapter protein beta GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0016301//kinase activity;GO:0032550 GO:0032989;GO:0006915//apoptotic process;GO:0006886//intracellular protein transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006996//organelle organization;GO:0022402//cell cycle process;GO:0045860//positive regulation of protein kinase activity;GO:0019217//regulation of fatty acid metabolic process;GO:0051403//stress-activated MAPK cascade "gi|148667693|gb|EDL00110.1|/0/mCG117847, isoform CRA_g, partial [Mus musculus]" 68198 455 175.76 186.39 0.084717685 Up 0.239093234 Ndufb2 "NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2" K03958|1|5e-47|187|mmu:68198|NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2 GO:0005746//mitochondrial respiratory chain GO:0050136//NADH dehydrogenase (quinone) activity GO:0051234//establishment of localization;GO:0022904//respiratory electron transport chain "gi|13386096|ref|NP_080888.1|/4.2938e-46/NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial precursor [Mus musculus]" 224092 2373 8.416666667 9.156666667 0.121573523 Up 0.239046222 Lsg1 large 60S subunit nuclear export GTPase 1 K14539|1|0.0|1234|mmu:224092|large subunit GTPase 1 [EC:3.6.1.-] - - - - 270151 3687.13 8.786666667 9.53 0.11716025 Up 0.239046222 Nlrx1 NLR family member X1 K12653|1|0.0|1919|mmu:270151|NLR family member X1 GO:0031966//mitochondrial membrane GO:0032550 GO:0006952//defense response;GO:0001818//negative regulation of cytokine production gi|255522931|ref|NP_848507.2|/0/NLR family member X1 [Mus musculus] 109108 3410 34.77333333 32.76666667 -0.085752453 Down 0.239046222 Slc30a9 "solute carrier family 30 (zinc transporter), member 9" "K14696|1|0.0|1038|mmu:109108|solute carrier family 30 (zinc transporter), member 9" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0005102//receptor binding;GO:0003713//transcription coactivator activity;GO:0015075//ion transmembrane transporter activity;GO:0005102//receptor binding;GO:0003713//transcription coactivator activity;GO:0015075//ion transmembrane transporter activity GO:0044763;GO:0000041//transition metal ion transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0044763;GO:0000041//transition metal ion transport;GO:0006366//transcription from RNA polymerase II promoter gi|125660458|ref|NP_848766.2|/0/zinc transporter 9 isoform 1 [Mus musculus] 99237 3895 18.04333333 16.87333333 -0.096720881 Down 0.238980405 Tm9sf4 transmembrane 9 superfamily protein member 4 K17086|1|0.0|1222|mmu:99237|transmembrane 9 superfamily member 2/4 - - - - 68097 2475.93 175.4466667 185.88 0.083339012 Up 0.238971003 Dynll2 dynein light chain LC8-type 2 K10418|1|2e-46|190|umr:103667356|dynein light chain LC8-type - - - "gi|119614889|gb|EAW94483.1|/4.1119e-60/dynein, light chain, LC8-type 2, isoform CRA_a, partial [Homo sapiens]" 22258 3661.01 34.24666667 32.26 -0.086217134 Down 0.238914589 Usp4 ubiquitin specific peptidase 4 (proto-oncogene) K11835|1|0.0|1826|mmu:22258|ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0016790//thiolester hydrolase activity;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0001664//G-protein coupled receptor binding GO:0010608//posttranscriptional regulation of gene expression;GO:0019941//modification-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0034613//cellular protein localization;GO:0070646//protein modification by small protein removal gi|164519045|ref|NP_035808.2|/0/ubiquitin carboxyl-terminal hydrolase 4 isoform 1 [Mus musculus] 12518 1327 0.343333333 0.536666667 0.644416351 Up 0.238848772 Cd79a CD79A antigen (immunoglobulin-associated alpha) K06506|1|2e-117|425|mmu:12518|CD79A antigen GO:0031224//intrinsic component of membrane;GO:0019814;GO:0009986//cell surface;GO:0005770//late endosome GO:0005488//binding;GO:0038023//signaling receptor activity GO:0030098//lymphocyte differentiation;GO:0042113//B cell activation;GO:0050851//antigen receptor-mediated signaling pathway gi|75677429|ref|NP_031681.2|/1.38105e-116/B-cell antigen receptor complex-associated protein alpha chain precursor [Mus musculus] 69780 2923 34.00666667 32.02333333 -0.086694113 Down 0.238792358 Smap2 small ArfGAP 2 K12486|1|0.0|743|mmu:69780|stromal membrane-associated protein GO:0031981//nuclear lumen GO:0046914//transition metal ion binding GO:0032012//regulation of ARF protein signal transduction gi|31981560|ref|NP_598477.2|/0/stromal membrane-associated protein 2 [Mus musculus] 78514 3038 31.69666667 33.67333333 0.087275412 Up 0.238792358 Arhgap10 Rho GTPase activating protein 10 K13736|1|0.0|1514|mmu:78514|Rho GTPase-activating protein 10 GO:0044444//cytoplasmic part GO:0008289//lipid binding GO:0006996//organelle organization;GO:0006915//apoptotic process;GO:0007154//cell communication gi|116174786|ref|NP_084389.2|/0/rho GTPase-activating protein 10 [Mus musculus] 320719 4325 1.35 1.64 0.280736408 Up 0.238782955 6030443J06Rik RIKEN cDNA 6030443J06 gene K04613|1|9e-08|62.8|rno:297590|vomeronasal 2 receptor - - - "gi|23484895|gb|EAA20074.1|/7.71395e-34/pORF1, partial [Plasmodium yoelii yoelii]" 171212 4725 5.17 4.663333333 -0.148802724 Down 0.238651322 Galnt10 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 K00710|1|0.0|1193|mmu:171212|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0006493//protein O-linked glycosylation gi|46877107|ref|NP_598950.2|/0/polypeptide N-acetylgalactosaminyltransferase 10 [Mus musculus] 103080 2135.91 5.2 4.693333333 -0.147898695 Down 0.238651322 10-Sep septin 10 K16940|1|0.0|817|mmu:103080|septin 10 GO:0032156//septin cytoskeleton;GO:0032156//septin cytoskeleton GO:0032550;GO:0032550 GO:0044763;GO:0044763 gi|67906175|ref|NP_001020082.1|/0/septin-10 isoform 2 [Mus musculus] 78100 2762 17.48666667 16.33 -0.098730516 Down 0.238585505 Msantd4 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils - GO:0043231//intracellular membrane-bounded organelle - - "gi|148677380|gb|EDL09327.1|/4.50697e-180/RIKEN cDNA 8430410K20, partial [Mus musculus]" 19159 3749 17.08333333 15.92 -0.101749168 Down 0.238585505 Cyth3 cytohesin 3 K18441|1|0.0|746|rno:116693|cytohesin - - - gi|60360638|dbj|BAD90330.1|/0/mKIAA4241 protein [Mus musculus] 20770 651 0.083333333 0.223333333 1.422233001 Up 0.238576103 Mucl2 mucin-like 2 - - - - - 19663 1711.41 164.77 174.0966667 0.079434989 Up 0.238538493 Rbpms RNA binding protein gene with multiple splicing - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0036094//small molecule binding;GO:0003729//mRNA binding;GO:0003712//transcription cofactor activity;GO:0036094//small molecule binding;GO:0003729//mRNA binding;GO:0003712//transcription cofactor activity;GO:0036094//small molecule binding;GO:0003729//mRNA binding;GO:0003712//transcription cofactor activity;GO:0036094//small molecule binding;GO:0003729//mRNA binding "GO:0001934//positive regulation of protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0007184//SMAD protein import into nucleus;GO:0001934//positive regulation of protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0007184//SMAD protein import into nucleus;GO:0001934//positive regulation of protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0007184//SMAD protein import into nucleus;GO:0001934//positive regulation of protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0007184//SMAD protein import into nucleus" gi|33342267|ref|NP_062707.1|/5.55832e-92/RNA-binding protein with multiple splicing isoform 1 [Mus musculus] 13850 2064.33 156.0333333 165.36 0.08375603 Up 0.238538493 Ephx2 "epoxide hydrolase 2, cytoplasmic" K08726|1|0.0|1122|mmu:13850|soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76] GO:0031981//nuclear lumen;GO:0042579//microbody;GO:0005924//cell-substrate adherens junction;GO:0031981//nuclear lumen;GO:0042579//microbody;GO:0005924//cell-substrate adherens junction;GO:0031981//nuclear lumen;GO:0042579//microbody;GO:0005924//cell-substrate adherens junction;GO:0031981//nuclear lumen;GO:0042579//microbody;GO:0005924//cell-substrate adherens junction GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0016791//phosphatase activity;GO:0016803;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0016791//phosphatase activity;GO:0016803;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0016791//phosphatase activity;GO:0016803;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0016791//phosphatase activity;GO:0016803 GO:0055092//sterol homeostasis;GO:0007600//sensory perception;GO:0002538;GO:0016311//dephosphorylation;GO:0008217//regulation of blood pressure;GO:0042221//response to chemical;GO:0019218//regulation of steroid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0010467//gene expression;GO:0009810;GO:0055092//sterol homeostasis;GO:0007600//sensory perception;GO:0002538;GO:0016311//dephosphorylation;GO:0008217//regulation of blood pressure;GO:0042221//response to chemical;GO:0019218//regulation of steroid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0010467//gene expression;GO:0009810;GO:0055092//sterol homeostasis;GO:0007600//sensory perception;GO:0002538;GO:0016311//dephosphorylation;GO:0008217//regulation of blood pressure;GO:0042221//response to chemical;GO:0019218//regulation of steroid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0010467//gene expression;GO:0009810;GO:0055092//sterol homeostasis;GO:0007600//sensory perception;GO:0002538;GO:0016311//dephosphorylation;GO:0008217//regulation of blood pressure;GO:0042221//response to chemical;GO:0019218//regulation of steroid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0010467//gene expression;GO:0009810 gi|406647876|ref|NP_001258332.1|/0/bifunctional epoxide hydrolase 2 isoform c precursor [Mus musculus] 69202 1155 165.6466667 156.3366667 -0.083452989 Down 0.238519689 Ptms parathymosin - - - - gi|821033098|ref|XP_012357729.1|/4.15375e-20/PREDICTED: parathymosin [Nomascus leucogenys] 100502946 3172 0.216666667 0.39 0.847996907 Up 0.238510286 Gm16796 "predicted gene, 16796" - - - - - 14404 2791 0.383333333 0.213333333 -0.845490051 Down 0.238510286 Gabre "gamma-aminobutyric acid (GABA) A receptor, subunit epsilon" K05185|1|0.0|895|mmu:14404|gamma-aminobutyric acid receptor subunit epsilon GO:0097060//synaptic membrane;GO:0034702//ion channel complex GO:0005253//anion channel activity;GO:0016917//GABA receptor activity;GO:0015276//ligand-gated ion channel activity GO:0042221//response to chemical;GO:0015698//inorganic anion transport;GO:0007186//G-protein coupled receptor signaling pathway "gi|148694615|gb|EDL26562.1|/0/gamma-aminobutyric acid (GABA-A) receptor, subunit epsilon [Mus musculus]" 118454 2188 0.383333333 0.213333333 -0.845490051 Down 0.238510286 Gjc2 "gap junction protein, gamma 2" "K07619|1|2e-77|293|mmu:118454|gap junction protein, alpha 12" GO:0044464;GO:0005921//gap junction;GO:0044425;GO:0044464;GO:0005921//gap junction;GO:0044425 - GO:0007154//cell communication;GO:0042221//response to chemical;GO:0007154//cell communication;GO:0042221//response to chemical gi|254028244|ref|NP_536702.3|/1.58056e-76/gap junction gamma-2 protein [Mus musculus] 19866 62 9.5 8.766666667 -0.11589912 Down 0.238482079 Rnu7 U7 small nuclear RNA - - - - - 106344 1231 3.103333333 3.526666667 0.184486555 Up 0.238463274 Rfc4 replication factor C (activator 1) 4 K10755|1|0.0|711|mmu:106344|replication factor C subunit 2/4 GO:0005657//replication fork;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0016462//pyrophosphatase activity;GO:0032550 GO:0006259//DNA metabolic process gi|21703948|ref|NP_663455.1|/0/replication factor C subunit 4 [Mus musculus] 12421 7046 3.586666667 3.166666667 -0.179678659 Down 0.238463274 Rb1cc1 RB1-inducible coiled-coil 1 K17589|1|0.0|2750|mmu:12421|RB1-inducible coiled-coil protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0000407//pre-autophagosomal structure;GO:0043234//protein complex GO:0019900//kinase binding "GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0001932//regulation of protein phosphorylation;GO:0008361//regulation of cell size;GO:0006914//autophagy;GO:0044767//single-organism developmental process;GO:0051403//stress-activated MAPK cascade" gi|226693374|ref|NP_033956.2|/0/RB1-inducible coiled-coil protein 1 [Mus musculus] 72135 1745 3.1 3.516666667 0.181940378 Up 0.238463274 Pygo1 pygopus 1 K06279|1|5e-27|125|fpg:101919976|SHC-transforming protein 1;K19758|3|7e-08|61.6|pss:102452344|dyslexia susceptibility 1 candidate gene 1 protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding GO:0033365//protein localization to organelle;GO:0007166//cell surface receptor signaling pathway;GO:0007275//multicellular organism development;GO:0006366//transcription from RNA polymerase II promoter gi|99028874|ref|NP_082392.1|/0/pygopus homolog 1 [Mus musculus] 277333 3581 0.816666667 1.06 0.376245016 Up 0.23844447 Gm5069 glyceraldehyde-3-phosphate dehydrogenase pseudogene K00134|1|7e-179|630|mmu:14433|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0015631//tubulin binding" GO:0007010//cytoskeleton organization;GO:0070997//neuron death;GO:0031647//regulation of protein stability;GO:0012501//programmed cell death;GO:0006412//translation;GO:0006007//glucose catabolic process;GO:0018119//peptidyl-cysteine S-nitrosylation;GO:0044710;GO:1901698//response to nitrogen compound;GO:0034341//response to interferon-gamma;GO:0032502//developmental process gi|576080555|ref|NP_001276655.1|/0/glyceraldehyde-3-phosphate dehydrogenase isoform 1 [Mus musculus] 100504191 5404 1.036666667 0.796666667 -0.379903962 Down 0.23844447 Gm16576 predicted gene 16576 - - - - - 22196 2539.03 30.24666667 32.19666667 0.090135174 Up 0.238425665 Ube2i ubiquitin-conjugating enzyme E2I K10577|1|3e-94|349|ccw:104684907|ubiquitin-conjugating enzyme E2 I - - - gi|672066800|ref|XP_008765771.1|/9.7192e-97/PREDICTED: SUMO-conjugating enzyme UBC9 isoform X2 [Rattus norvegicus] 14680 5536.61 1.52 1.816666667 0.257222405 Up 0.23840686 Gnal "guanine nucleotide binding protein, alpha stimulating, olfactory type" K04633|1|0.0|788|rno:24611|guanine nucleotide-binding protein G(olf) subunit alpha - - - gi|47271350|ref|NP_034437.1|/0/guanine nucleotide-binding protein G(olf) subunit alpha isoform 1 [Mus musculus] 15201 3039 0.176666667 0.046666667 -1.920565533 Down 0.238388055 Hells "helicase, lymphoid specific" K19001|1|0.0|1456|mmu:15201|ATP-dependent DNA helicase "GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region" GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding GO:0031055//chromatin remodeling at centromere;GO:0006305;GO:0006915//apoptotic process;GO:0006342//chromatin silencing;GO:0002521//leukocyte differentiation;GO:0000087//mitotic M phase;GO:0032943//mononuclear cell proliferation gi|12232371|ref|NP_032260.2|/0/lymphocyte-specific helicase [Mus musculus] 67568 1630 149.3066667 158.29 0.084291531 Up 0.238388055 Mrfap1 Morf4 family associated protein 1 K07190|1|4e-17|92.0|lve:103075354|phosphorylase kinase alpha/beta subunit GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding GO:0019318//hexose metabolic process gi|33086610|gb|AAP92617.1|/4.44454e-54/Ab2-450 [Rattus norvegicus] 18194 2218 3.95 3.506666667 -0.171752354 Down 0.238359848 Nsdhl NAD(P) dependent steroid dehydrogenase-like K07748|1|0.0|698|mmu:18194|sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) [EC:1.1.1.170] - - - - 72960 2011 3.83 3.393333333 -0.174641237 Down 0.238359848 Top1mt "DNA topoisomerase 1, mitochondrial" K03163|1|0.0|1175|mmu:72960|DNA topoisomerase I [EC:5.99.1.2] - - - "gi|50657345|ref|NP_082680.1|/0/DNA topoisomerase I, mitochondrial [Mus musculus]" 70227 5978 4.013333333 3.57 -0.168876912 Down 0.238359848 Zfp619 zinc finger protein 619 K09228|1|0.0|2482|mmu:70227|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|160333308|ref|NP_001004139.2|/0/zinc finger protein 91 [Mus musculus] 269180 5591.63 4.06 3.616666667 -0.166819091 Down 0.238359848 Inpp4a "inositol polyphosphate-4-phosphatase, type I" K01109|1|0.0|1292|ptr:470448|inositol polyphosphate-4-phosphatase [EC:3.1.3.66] - - - "gi|595763431|ref|NP_001277726.1|/0/type I inositol 3,4-bisphosphate 4-phosphatase isoform 3 [Mus musculus]" 26436 4421 6.896666667 7.53 0.126750626 Up 0.238350446 Psg16 pregnancy specific glycoprotein 16 K06499|1|3e-117|425|mmu:384557|carcinoembryonic antigen-related cell adhesion molecule - GO:0005515//protein binding GO:0001525//angiogenesis;GO:0038044;GO:0010467//gene expression;GO:0009690//cytokinin metabolic process;GO:0032653 gi|568945808|ref|XP_006540064.1|/0/PREDICTED: pregnancy specific glycoprotein 16 isoform X1 [Mus musculus] 243371 2858.34 6.913333333 7.546666667 0.126458064 Up 0.238350446 Lrrc61 leucine rich repeat containing 61 K10044|1|8e-13|79.0|mmu:71660|retinoic acid receptor responder protein 2 - - - - 57276 1170 6.92 7.55 0.125704607 Up 0.238350446 Vsig2 V-set and immunoglobulin domain containing 2 "K06791|1|1e-33|146|pbi:103064358|immunoglobulin superfamily, member 11" GO:0031224//intrinsic component of membrane - - gi|114145511|ref|NP_065264.2|/9.91975e-169/V-set and immunoglobulin domain-containing protein 2 precursor [Mus musculus] 19340 3849.92 7.55 6.916666667 -0.126399714 Down 0.238350446 Rab3d "RAB3D, member RAS oncogene family" K07884|1|3e-107|393|mmu:19340|Ras-related protein Rab-3D - - - - 69046 1915 151.4966667 160.1166667 0.079837436 Up 0.238247019 Isca1 iron-sulfur cluster assembly 1 K13628|1|1e-70|270|nle:100601021|iron-sulfur cluster assembly protein - - - - 16562 6764 168.9266667 160.3633333 -0.075052778 Down 0.238247019 Kif1c kinesin family member 1C K10392|1|0.0|1836|mmu:16562|kinesin family member 1 GO:0005875//microtubule associated complex;GO:0043231//intracellular membrane-bounded organelle GO:0003774//motor activity;GO:0032550 GO:0006928//movement of cell or subcellular component;GO:0048193//Golgi vesicle transport gi|50510599|dbj|BAD32285.1|/0/mKIAA0706 protein [Mus musculus] 435391 1103 0.183333333 0.05 -1.874469118 Down 0.238237617 Dupd1 dual specificity phosphatase and pro isomerase domain containing 1 K14165|1|3e-123|443|mmu:435391|atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] - - - gi|85701508|ref|NP_001013848.1|/2.85489e-122/dual specificity phosphatase DUPD1 [Mus musculus] 100038468 2203 0.05 0.183333333 1.874469118 Up 0.238237617 Gm10684 predicted gene 10684 - - - - - 98388 3135 0.173333333 0.046666667 -1.893084796 Down 0.238237617 Chst10 carbohydrate sulfotransferase 10 K09674|1|0.0|782|mmu:98388|carbohydrate 3-sulfotransferase 10 [EC:2.8.2.-] GO:0031224//intrinsic component of membrane GO:0008146//sulfotransferase activity GO:0044723;GO:0007613//memory "gi|148682602|gb|EDL14549.1|/0/carbohydrate sulfotransferase 10, isoform CRA_b, partial [Mus musculus]" 69035 6987 5.33 5.89 0.144132101 Up 0.238228215 Zdhhc3 "zinc finger, DHHC domain containing 3" K20029|1|9e-162|575|mmu:69035|palmitoyltransferase ZDHHC3/7/25 [EC:2.3.1.225] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system "GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0046914//transition metal ion binding" GO:0006886//intracellular protein transport;GO:0006497//protein lipidation gi|27754040|ref|NP_081193.2|/7.61203e-161/palmitoyltransferase ZDHHC3 [Mus musculus] 56449 1685.88 147.7233333 156.2566667 0.081020021 Up 0.238228215 Ybx3 Y box protein 3 K06099|1|3e-108|395|mmu:56449|cold shock domain protein A GO:0005911//cell-cell junction;GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex;GO:0005911//cell-cell junction;GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0043566//structure-specific DNA binding;GO:0003729//mRNA binding;GO:0043566//structure-specific DNA binding;GO:0003729//mRNA binding "GO:0035265//organ growth;GO:0070265//necrotic cell death;GO:0008406//gonad development;GO:0006915//apoptotic process;GO:0006972//hyperosmotic response;GO:0043009//chordate embryonic development;GO:0034612//response to tumor necrosis factor;GO:0007519//skeletal muscle tissue development;GO:0009887//organ morphogenesis;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0035265//organ growth;GO:0070265//necrotic cell death;GO:0008406//gonad development;GO:0006915//apoptotic process;GO:0006972//hyperosmotic response;GO:0043009//chordate embryonic development;GO:0034612//response to tumor necrosis factor;GO:0007519//skeletal muscle tissue development;GO:0048232//male gamete generation" gi|47059495|ref|NP_620817.2|/2.42071e-107/Y-box-binding protein 3 long isoform [Mus musculus] 66625 4545 6.153333333 5.59 -0.138519864 Down 0.238228215 Pnisr PNN interacting serine/arginine-rich "K13170|1|2e-164|583|umr:103675875|splicing factor, arginine/serine-rich 18" - - - - 69748 2586 6.083333333 5.526666667 -0.138452457 Down 0.238228215 Aldh16a1 "aldehyde dehydrogenase 16 family, member A1" K00128|1|1e-172|609|xtr:733905|aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] - - - "gi|148690867|gb|EDL22814.1|/0/aldehyde dehydrogenase 16 family, member A1, isoform CRA_a, partial [Mus musculus]" 17220 2396 5.68 6.243333333 0.136425564 Up 0.238228215 Mcm7 minichromosome maintenance complex component 7 K02210|1|0.0|1393|mmu:17220|DNA replication licensing factor MCM7 [EC:3.6.4.12] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0003678//DNA helicase activity;GO:0032550;GO:0042623//ATPase activity, coupled;GO:0043566//structure-specific DNA binding" "GO:0070849//response to epidermal growth factor;GO:0033554//cellular response to stress;GO:0006261//DNA-dependent DNA replication;GO:0016310//phosphorylation;GO:0006351//transcription, DNA-templated" gi|10242373|ref|NP_032594.1|/0/DNA replication licensing factor MCM7 [Mus musculus] 67542 2920 31.98333333 30.05 -0.089955315 Down 0.2381718 Cog6 component of oligomeric golgi complex 6 K20293|1|0.0|1213|mmu:67542|conserved oligomeric Golgi complex subunit 6 - - - gi|160333744|ref|NP_080501.2|/0/conserved oligomeric Golgi complex subunit 6 [Mus musculus] 72157 2334 151.63 160.0233333 0.077727064 Up 0.238143593 Pgm2 phosphoglucomutase 2 K01835|1|0.0|1062|mmu:72157|phosphoglucomutase [EC:5.4.2.2] - - - gi|148698933|gb|EDL30880.1|/0/phosphoglucomutase 2 [Mus musculus] 15402 1877 0.083333333 0.22 1.40053793 Up 0.238124788 Hoxa5 homeobox A5 K09305|1|2e-158|561|rno:79241|homeobox protein HoxA/B/C5 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0007275//multicellular organism development;GO:0010467//gene expression gi|564303752|ref|XP_003753945.2|/1.51112e-157/PREDICTED: homeobox protein Hox-A5 [Rattus norvegicus] 56612 708 140.8133333 148.99 0.081431556 Up 0.238030765 Pfdn5 prefoldin 5 K04797|1|8e-73|275|myb:102258537|prefoldin alpha subunit GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0005515//protein binding "GO:0043010//camera-type eye development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006458//'de novo' protein folding" gi|7209590|dbj|BAA92269.1|/1.20454e-72/EIG-1 [Mus musculus] 67685 1618 0.42 0.62 0.561878888 Up 0.237983753 Dyx1c1 dyslexia susceptibility 1 candidate 1 K19758|1|1e-116|422|mmu:67685|dyslexia susceptibility 1 candidate gene 1 protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0035258//steroid hormone receptor binding;GO:0035258//steroid hormone receptor binding GO:0048731//system development;GO:0010498//proteasomal protein catabolic process;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0048731//system development;GO:0010498//proteasomal protein catabolic process;GO:0030520//intracellular estrogen receptor signaling pathway gi|255683353|ref|NP_080590.3|/0/dyslexia susceptibility 1 candidate gene 1 protein homolog isoform 1 [Mus musculus] 18607 7135.27 4.37 3.903333333 -0.16292661 Down 0.237889729 Pdpk1 3-phosphoinositide dependent protein kinase 1 K06276|1|0.0|1001|mmu:18607|3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0005924//cell-substrate adherens junction;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0005924//cell-substrate adherens junction;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0005924//cell-substrate adherens junction GO:0004674//protein serine/threonine kinase activity;GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0032550 "GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0030334//regulation of cell migration;GO:0032868//response to insulin;GO:0002886;GO:0007010//cytoskeleton organization;GO:0048017//inositol lipid-mediated signaling;GO:0050851//antigen receptor-mediated signaling pathway;GO:0032147//activation of protein kinase activity;GO:0006351//transcription, DNA-templated;GO:0001933//negative regulation of protein phosphorylation;GO:0006970//response to osmotic stress;GO:0007599//hemostasis;GO:0007267//cell-cell signaling;GO:0002224//toll-like receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007044//cell-substrate junction assembly;GO:0010659//cardiac muscle cell apoptotic process;GO:0003309//type B pancreatic cell differentiation;GO:0038127//ERBB signaling pathway;GO:0051130//positive regulation of cellular component organization;GO:0031294//lymphocyte costimulation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0030334//regulation of cell migration;GO:0032868//response to insulin;GO:0002886;GO:0032147//activation of protein kinase activity;GO:0006351//transcription, DNA-templated;GO:0001933//negative regulation of protein phosphorylation;GO:0006970//response to osmotic stress;GO:0002224//toll-like receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007044//cell-substrate junction assembly;GO:0010659//cardiac muscle cell apoptotic process;GO:0003309//type B pancreatic cell differentiation;GO:0051130//positive regulation of cellular component organization;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0030334//regulation of cell migration;GO:0032868//response to insulin;GO:0002886;GO:0032147//activation of protein kinase activity;GO:0006351//transcription, DNA-templated;GO:0001933//negative regulation of protein phosphorylation;GO:0006970//response to osmotic stress;GO:0002224//toll-like receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007044//cell-substrate junction assembly;GO:0010659//cardiac muscle cell apoptotic process;GO:0003309//type B pancreatic cell differentiation;GO:0051130//positive regulation of cellular component organization" gi|124107598|ref|NP_001074242.1|/0/3-phosphoinositide-dependent protein kinase 1 isoform B [Mus musculus] 17002 2742 0.053333333 0.186666667 1.807354922 Up 0.237833315 Ltf lactotransferrin K17283|1|0.0|1425|mmu:17002|lactotransferrin [EC:3.4.21.-] "GO:0016023//cytoplasmic, membrane-bounded vesicle" "GO:0005506//iron ion binding;GO:0005539//glycosaminoglycan binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0000041//transition metal ion transport;GO:0006875//cellular metal ion homeostasis gi|31560677|ref|NP_032548.2|/0/lactotransferrin precursor [Mus musculus] 101243624 1668 0.713333333 0.503333333 -0.503062247 Down 0.237823912 Gm29811 "predicted gene, 29811" K04079|1|1e-52|145|ptr:743883|molecular chaperone HtpG - GO:0005488//binding;GO:0005488//binding - gi|148727313|ref|NP_001092042.1|/8.33929e-52/heat shock protein HSP 90-alpha [Pan troglodytes] 19177 969 131.7833333 139.4733333 0.081821388 Up 0.237748693 Psmb7 "proteasome (prosome, macropain) subunit, beta type 7" K02739|1|3e-147|523|mmu:19177|20S proteasome subunit beta 2 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity GO:0006508//proteolysis "gi|148694875|gb|EDL26822.1|/6.01139e-147/proteasome (prosome, macropain) subunit, beta type 7, isoform CRA_b, partial [Mus musculus]" 72982 1468.47 2.056666667 1.736666667 -0.243987117 Down 0.237739291 Tmem138 transmembrane protein 138 - GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0010927;GO:0010927 gi|562884419|ref|XP_006169696.1|/3.38119e-23/PREDICTED: transmembrane protein 138 isoform X1 [Tupaia chinensis] 381694 4543 1.376666667 1.106666667 -0.31495854 Down 0.237729888 B3glct beta-3-glucosyltransferase "K13675|1|0.0|897|mmu:381694|UDP-glucose:O-linked fucose beta-1,3-glucosyltransferase [EC:2.4.1.-]" - - - "gi|568939299|ref|XP_006504998.1|/0/PREDICTED: beta-1,3-glucosyltransferase isoform X1 [Mus musculus]" 20589 5562 1.406666667 1.136666667 -0.30747126 Down 0.237729888 Ighmbp2 immunoglobulin mu binding protein 2 K19036|1|0.0|1771|mmu:20589|ATP-dependent RNA/DNA helicase IGHMBP2 [EC:3.6.4.12 3.6.4.13] GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0046914//transition metal ion binding;GO:0032550;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0003723//RNA binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0004004//ATP-dependent RNA helicase activity" GO:0006366//transcription from RNA polymerase II promoter;GO:0051259//protein oligomerization;GO:0021515//cell differentiation in spinal cord gi|74191771|dbj|BAE32841.1|/0/unnamed protein product [Mus musculus] 100503166 483 0.22 0.393333333 0.83824893 Up 0.237664072 1700048M11Rik RIKEN cDNA 1700048M11 gene - - - - - 77300 9117 12.07333333 11.19666667 -0.108754751 Down 0.237664072 Raph1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 K17704|1|9e-111|405|mdo:100025059|amyloid beta A4 precursor protein-binding family B member 1-interacting protein - - - - 12928 5943.53 12.00666667 11.13 -0.109382088 Down 0.237664072 Crk v-crk avian sarcoma virus CT10 oncogene homolog K04438|1|5e-27|127|mdo:100012317|proto-oncogene C-crk - - - - 69953 1194 31.21333333 29.33 -0.089785363 Down 0.237598255 2810025M15Rik RIKEN cDNA 2810025M15 gene K02921|1|1e-17|93.2|ocu:100353361|large subunit ribosomal protein L37Ae - - - - 228994 3199 15.26 16.38666667 0.102767453 Up 0.237588853 Ythdf1 YTH domain family 1 K20102|1|0.0|912|mmu:228994|YTH domain-containing family protein - - - gi|30424609|ref|NP_776122.1|/0/YTH domain-containing family protein 1 [Mus musculus] 102626 2816 15.31666667 16.44333333 0.102400426 Up 0.237588853 Mapkapk3 mitogen-activated protein kinase-activated protein kinase 3 K04444|1|2e-142|385|oaa:100075476|mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004672//protein kinase activity GO:0006468//protein phosphorylation;GO:0006907//pinocytosis;GO:0002221//pattern recognition receptor signaling pathway;GO:0002237//response to molecule of bacterial origin "gi|148689230|gb|EDL21177.1|/0/mitogen-activated protein kinase-activated protein kinase 3, isoform CRA_c, partial [Mus musculus]" 67383 2138 27.61 29.48333333 0.094708754 Up 0.237532438 Carnmt1 carnosine N-methyltransferase 1 K19787|1|0.0|760|mmu:67383|carnosine N-methyltransferase [EC:2.1.1.22] - - - gi|31981066|ref|NP_080396.2|/0/carnosine N-methyltransferase [Mus musculus] 17308 2847.89 28.39666667 30.26666667 0.092008207 Up 0.237532438 Mgat1 mannoside acetylglucosaminyltransferase 1 "K00726|1|0.0|855|mmu:17308|alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.101]" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0008375//acetylglucosaminyltransferase activity;GO:0043169//cation binding;GO:0008375//acetylglucosaminyltransferase activity;GO:0043169//cation binding;GO:0008375//acetylglucosaminyltransferase activity;GO:0043169//cation binding;GO:0008375//acetylglucosaminyltransferase activity GO:0043009//chordate embryonic development;GO:0006464//cellular protein modification process;GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0043009//chordate embryonic development;GO:0006464//cellular protein modification process;GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0043009//chordate embryonic development;GO:0006464//cellular protein modification process;GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0043009//chordate embryonic development;GO:0006464//cellular protein modification process;GO:0006047//UDP-N-acetylglucosamine metabolic process "gi|158711696|ref|NP_034924.3|/0/alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase [Mus musculus]" 71240 3786 2.3 2.656666667 0.207983362 Up 0.237523036 Osbpl7 oxysterol binding protein-like 7 K20463|1|0.0|1604|mmu:71240|oxysterol-binding protein-related protein 3/6/7 - - - gi|887235639|ref|NP_001297438.1|/0/oxysterol-binding protein-related protein 7 isoform 1 [Mus musculus] 216459 1053 2.62 2.263333333 -0.211117738 Down 0.237523036 Myl6b "myosin, light polypeptide 6B" K12751|1|1e-91|338|mcf:102116753|myosin light chain 6 GO:0016459//myosin complex GO:0046872//metal ion binding;GO:0005198//structural molecule activity GO:0014706//striated muscle tissue development;GO:0006936//muscle contraction gi|537270019|gb|ERE91720.1|/5.18476e-94/myosin light chain 6B-like protein [Cricetulus griseus] 21350 1144 0.093333333 0.236666667 1.342392197 Up 0.237513633 Tal2 T cell acute lymphocytic leukemia 2 K09068|1|7e-50|200|mmu:21350|T-cell acute lymphocytic leukemia protein - GO:0003676//nucleic acid binding;GO:0005515//protein binding "GO:0050896//response to stimulus;GO:0040007//growth;GO:0021536//diencephalon development;GO:0006351//transcription, DNA-templated" gi|111126|pir||B41629/8.09474e-51/TAL2 protein - mouse (fragment) 54198 1377 119.62 126.7866667 0.083944412 Up 0.237494829 Snx3 sorting nexin 3 K17918|1|2e-89|332|tup:102479211|sorting nexin-3/12 GO:0005768//endosome;GO:0031090//organelle membrane GO:1901981//phosphatidylinositol phosphate binding;GO:0019902//phosphatase binding GO:0044763;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport gi|947288638|ref|XP_014446547.1|/1.68255e-88/PREDICTED: sorting nexin-3 [Tupaia chinensis] 72199 3965 6.373333333 6.99 0.133244338 Up 0.237485426 Mms19 MMS19 (MET18 S. cerevisiae) K15075|1|0.0|1865|mmu:72199|DNA repair/transcription protein MET18/MMS19 GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle GO:0035258//steroid hormone receptor binding "GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006351//transcription, DNA-templated" gi|15100156|ref|NP_082428.1|/0/MMS19 nucleotide excision repair protein homolog [Mus musculus] 100038575 3721 0.546666667 0.356666667 -0.616085018 Down 0.237466622 Gm10635 predicted gene 10635 K17495|1|1e-07|62.0|bom:106701751|CUB and sushi domain-containing protein;K19941|2|2e-06|58.2|lcm:102351696|synapsin - - - gi|45478100|gb|AAS66221.1|/6.60464e-30/LRRG00130 [Rattus norvegicus] 15980 2070 124.38 117.3333333 -0.084141594 Down 0.237429012 Ifngr2 interferon gamma receptor 2 K05133|1|0.0|642|mmu:15980|interferon gamma receptor 2 GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane GO:0004904//interferon receptor activity GO:0051707//response to other organism;GO:0001959//regulation of cytokine-mediated signaling pathway gi|6680373|ref|NP_032364.1|/0/interferon gamma receptor 2 precursor [Mus musculus] 16906 2871 1.916666667 2.246666667 0.229186635 Up 0.23741961 Lmnb1 lamin B1 K07611|1|0.0|899|mmu:16906|lamin B GO:0034399//nuclear periphery;GO:0005882//intermediate filament;GO:0019866//organelle inner membrane;GO:0012505//endomembrane system GO:0019901//protein kinase binding GO:0031660//regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle;GO:0007254//JNK cascade gi|188219589|ref|NP_034851.2|/0/lamin-B1 [Mus musculus] 240613 8026 2.266666667 1.933333333 -0.229481846 Down 0.23741961 9930021J03Rik RIKEN cDNA 9930021J03 gene - - - - gi|295293085|ref|NP_766424.2|/0/uncharacterized protein KIAA2026 homolog [Mus musculus] 52829 1699 2.256666667 1.926666667 -0.228086341 Down 0.23741961 Lurap1l leucine rich adaptor protein 1-like - - - - "gi|148699098|gb|EDL31045.1|/9.66766e-92/DNA segment, Chr 4, Brigham & Women's Genetics 0951 expressed, partial [Mus musculus]" 100037260 1689 0.443333333 0.266666667 -0.733354341 Down 0.237269171 9430060I03Rik RIKEN cDNA 9430060I03 gene K08579|1|1e-19|100|ptr:460069|calpain-10 [EC:3.4.22.-] - - - - 54648 3641 0.446666667 0.27 -0.726239188 Down 0.237269171 Ccdc120 coiled-coil domain containing 120 - - - - gi|625204821|ref|XP_003505138.2|/0/PREDICTED: LOW QUALITY PROTEIN: coiled-coil domain-containing protein 120 isoform X1 [Cricetulus griseus] 50791 6736 1.306666667 1.05 -0.315501826 Down 0.237240964 Magi2 "membrane associated guanylate kinase, WW and PDZ domain containing 2" K05629|1|0.0|2396|mmu:50791|atrophin-1 interacting protein 1 GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0044327//dendritic spine head;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0036056;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0044327//dendritic spine head;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0036056;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0044327//dendritic spine head;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0036056;GO:0044444//cytoplasmic part GO:0070697//activin receptor binding;GO:0060089;GO:0031690//adrenergic receptor binding;GO:0019904//protein domain specific binding;GO:0019899//enzyme binding;GO:0032947//protein complex scaffold;GO:0070697//activin receptor binding;GO:0060089;GO:0031690//adrenergic receptor binding;GO:0019904//protein domain specific binding;GO:0019899//enzyme binding;GO:0032947//protein complex scaffold;GO:0070697//activin receptor binding;GO:0060089;GO:0031690//adrenergic receptor binding;GO:0019904//protein domain specific binding;GO:0019899//enzyme binding;GO:0032947//protein complex scaffold GO:0002090//regulation of receptor internalization;GO:0008283//cell proliferation;GO:0072657//protein localization to membrane;GO:0007050//cell cycle arrest;GO:0097205//renal filtration;GO:0051259//protein oligomerization;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0010922//positive regulation of phosphatase activity;GO:0032924//activin receptor signaling pathway;GO:0016477//cell migration;GO:0002090//regulation of receptor internalization;GO:0008283//cell proliferation;GO:0072657//protein localization to membrane;GO:0007050//cell cycle arrest;GO:0097205//renal filtration;GO:0051259//protein oligomerization;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0010922//positive regulation of phosphatase activity;GO:0032924//activin receptor signaling pathway;GO:0016477//cell migration;GO:0002090//regulation of receptor internalization;GO:0008283//cell proliferation;GO:0072657//protein localization to membrane;GO:0007050//cell cycle arrest;GO:0097205//renal filtration;GO:0051259//protein oligomerization;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0010922//positive regulation of phosphatase activity;GO:0032924//activin receptor signaling pathway;GO:0016477//cell migration "gi|568933263|ref|XP_006535811.1|/0/PREDICTED: membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X6 [Mus musculus]" 67708 4420 1.323333333 1.063333333 -0.315582583 Down 0.237240964 Pcnx4 pecanex homolog 4 - - - - gi|124430539|ref|NP_080603.2|/0/pecanex-like protein 4 [Mus musculus] 241556 3773 4.466666667 4.966666667 0.15307933 Up 0.237212757 Tspan18 tetraspanin 18 K17353|1|8e-122|441|mmu:241556|tetraspanin-18 GO:0031224//intrinsic component of membrane - - gi|34147226|ref|NP_899003.1|/6.77053e-121/tetraspanin-18 [Mus musculus] 76972 627 4.51 5.01 0.15168317 Up 0.237212757 Snhg20 small nucleolar RNA host gene 20 - - - - - 16009 2456 16.95 15.83 -0.098624018 Down 0.237175148 Igfbp3 insulin-like growth factor binding protein 3 K10138|1|3e-144|514|mmu:16009|insulin-like growth factor-binding protein 3 GO:0016942//insulin-like growth factor binding protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0072542//protein phosphatase activator activity;GO:0005520//insulin-like growth factor binding GO:0014909//smooth muscle cell migration;GO:0006915//apoptotic process;GO:0045445//myoblast differentiation;GO:0008285//negative regulation of cell proliferation;GO:0001932//regulation of protein phosphorylation;GO:0000165//MAPK cascade;GO:0009967//positive regulation of signal transduction;GO:0006006//glucose metabolic process;GO:0044093;GO:0016049//cell growth gi|111378400|ref|NP_032369.2|/2.93799e-143/insulin-like growth factor-binding protein 3 precursor [Mus musculus] 217463 6239 5.92 5.37 -0.140675088 Down 0.237128136 Snx13 sorting nexin 13 K17925|1|0.0|1801|bta:532001|sorting nexin-13 GO:0005768//endosome GO:0005543//phospholipid binding GO:0043087//regulation of GTPase activity;GO:0015031//protein transport;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway "gi|148704918|gb|EDL36865.1|/0/sorting nexin 13, isoform CRA_b, partial [Mus musculus]" 93710 4537 2.426666667 2.086666667 -0.217775793 Down 0.237128136 Pcdhga2 "protocadherin gamma subfamily A, 2" K16495|1|0.0|1675|mmu:93710|protocadherin gamma subfamily A GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|18087755|ref|NP_291063.1|/0/protocadherin gamma-A2 precursor [Mus musculus] 70005 4581 2.42 2.08 -0.218423519 Down 0.237128136 Znf41-ps "ZNF41, pseudogene" K09228|1|0.0|1228|mmu:666532|KRAB domain-containing zinc finger protein - - - - 68995 876 11.87333333 11 -0.110221492 Down 0.237118733 Mcts1 malignant T cell amplified sequence 1 K07575|1|2e-108|380|phd:102326206|PUA domain protein GO:0044424 GO:0003676//nucleic acid binding "GO:0033554//cellular response to stress;GO:0040007//growth;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation" gi|556716146|ref|XP_005953999.1|/1.33047e-107/PREDICTED: malignant T-cell-amplified sequence 1-like isoform X1 [Pantholops hodgsonii] 223776 2360 10.97 11.83666667 0.109699334 Up 0.237118733 Selo selenoprotein O K06103|1|8e-127|457|smm:Smp_131690|calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1] - - - - 56174 1330 11.55333333 10.68666667 -0.112497229 Down 0.237118733 Nagk N-acetylglucosamine kinase K00884|1|0.0|677|mmu:56174|N-acetylglucosamine kinase [EC:2.7.1.59] - "GO:0019200//carbohydrate kinase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032550;GO:0019200//carbohydrate kinase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032550" GO:0016310//phosphorylation;GO:1901071;GO:0006054//N-acetylneuraminate metabolic process;GO:0016310//phosphorylation;GO:1901071;GO:0006054//N-acetylneuraminate metabolic process "gi|148666691|gb|EDK99107.1|/0/N-acetylglucosamine kinase, isoform CRA_a [Mus musculus]" 68744 4139.83 11.04666667 11.92 0.109773134 Up 0.237118733 Zfp740 zinc finger protein 740 K09228|1|2e-19|101|nle:100586364|KRAB domain-containing zinc finger protein - - - gi|568993199|ref|XP_006521396.1|/1.19918e-97/PREDICTED: zinc finger protein 740 isoform X5 [Mus musculus] 109346 1887.53 3.13 2.743333333 -0.190232727 Down 0.237109331 Ankrd39 ankyrin repeat domain 39 K10799|1|4e-18|95.9|gga:374253|tankyrase [EC:2.4.2.30] - - - gi|58037099|ref|NP_080517.1|/3.60194e-103/ankyrin repeat domain-containing protein 39 isoform 1 [Mus musculus] 329977 4505 0.186666667 0.056666667 -1.719892081 Down 0.237099929 Fhad1 forkhead-associated (FHA) phosphopeptide binding domain 1 K20283|1|3e-22|110|fab:101821389|golgin subfamily A member 4 GO:0005615//extracellular space GO:0005515//protein binding GO:0001775//cell activation;GO:0043623//cellular protein complex assembly;GO:0007154//cell communication gi|209413705|ref|NP_808536.2|/0/forkhead-associated domain-containing protein 1 [Mus musculus] 78255 6914 0.8 1.036666667 0.373880175 Up 0.237071721 Ralgps2 Ral GEF with PH domain and SH3 binding motif 2 K04349|1|1e-30|139|xma:102236811|Ras-specific guanine nucleotide-releasing factor 1 GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0044424 GO:0030695//GTPase regulator activity;GO:0008289//lipid binding;GO:0030695//GTPase regulator activity;GO:0008289//lipid binding;GO:0030695//GTPase regulator activity;GO:0008289//lipid binding;GO:0030695//GTPase regulator activity;GO:0008289//lipid binding;GO:0030695//GTPase regulator activity;GO:0008289//lipid binding;GO:0030695//GTPase regulator activity;GO:0008289//lipid binding GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction;GO:0035556//intracellular signal transduction "gi|148707424|gb|EDL39371.1|/0/Ral GEF with PH domain and SH3 binding motif 2, isoform CRA_b, partial [Mus musculus]" 319887 2081 1.04 0.803333333 -0.372512883 Down 0.237071721 E030030I06Rik RIKEN cDNA E030030I06 gene K02091|1|5e-15|84.3|mmu:12571|cyclin-dependent kinase 6 [EC:2.7.11.22] GO:0016020//membrane;GO:0044424 GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity GO:0007165//signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0030217//T cell differentiation;GO:0042127//regulation of cell proliferation;GO:0010467//gene expression;GO:0006796//phosphate-containing compound metabolic process;GO:0030099//myeloid cell differentiation;GO:0048522;GO:0048523//negative regulation of cellular process;GO:0007049//cell cycle gi|363000610|ref|NP_001241674.1|/3.08383e-85/uncharacterized protein LOC319887 isoform 2 [Mus musculus] 78830 2924 123.9566667 117.4766667 -0.077461629 Down 0.237071721 Slc25a12 "solute carrier family 25 (mitochondrial carrier, Aralar), member 12" "K15105|1|0.0|1295|mmu:78830|solute carrier family 25 (mitochondrial aspartate/glutamate transporter), member 12/13" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0046872//metal ion binding GO:0044763;GO:0009152//purine ribonucleotide biosynthetic process;GO:0010038//response to metal ion;GO:0015740//C4-dicarboxylate transport;GO:0022904//respiratory electron transport chain gi|755500856|ref|XP_011238154.1|/0/PREDICTED: calcium-binding mitochondrial carrier protein Aralar1 isoform X1 [Mus musculus] 66898 3248 8.063333333 8.773333333 0.12174872 Up 0.236958893 Baiap2l1 BAI1-associated protein 2-like 1 K20127|1|0.0|1031|mmu:66898|BAI1-associated protein 2-like protein GO:0005856//cytoskeleton;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0016020//membrane "GO:0008092//cytoskeletal protein binding;GO:0030674//protein binding, bridging;GO:0019904//protein domain specific binding" GO:0051707//response to other organism;GO:0031532//actin cytoskeleton reorganization;GO:0030041//actin filament polymerization;GO:0007154//cell communication;GO:0030031//cell projection assembly gi|21313234|ref|NP_080109.1|/0/brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 [Mus musculus] 98932 1083 27.95 29.77 0.091010939 Up 0.236958893 Myl9 "myosin, light polypeptide 9, regulatory" K12755|1|6e-88|326|chx:102178087|myosin regulatory light chain 9 - - - gi|431894354|gb|ELK04154.1|/3.79015e-87/Myosin regulatory light polypeptide 9 [Pteropus alecto] 72388 3550 0.06 0.193333333 1.688055994 Up 0.236846064 Ripk4 receptor-interacting serine-threonine kinase 4 K08848|1|0.0|1345|mmu:72388|receptor-interacting serine/threonine-protein kinase 4 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0048729//tissue morphogenesis;GO:0006464//cellular protein modification process gi|18129624|ref|NP_076152.2|/0/receptor-interacting serine/threonine-protein kinase 4 [Mus musculus] 319163 452 0.01 0.103333333 3.36923381 Up 0.236827259 Hist1h2aa "histone cluster 1, H2aa" K11251|1|3e-66|251|mmu:319163|histone H2A - - - - 268949 2608 0.103333333 0.01 -3.36923381 Down 0.236827259 Dpcr1 diffuse panbronchiolitis critical region 1 (human) K10955|1|1e-13|81.6|asn:102388355|intestinal mucin-2 GO:0031224//intrinsic component of membrane - - gi|84370308|ref|NP_001028538.1|/0/diffuse panbronchiolitis critical region protein 1 homolog precursor [Mus musculus] 15497 1821 0.01 0.1 3.321928095 Up 0.236827259 Hsd3b6 "hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6" K00070|1|0.0|762|mmu:15497|3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1] GO:0031224//intrinsic component of membrane;GO:0005740//mitochondrial envelope;GO:0019866//organelle inner membrane "GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0036094//small molecule binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds" GO:0003006//developmental process involved in reproduction;GO:0006694//steroid biosynthetic process;GO:0006826//iron ion transport;GO:0051384//response to glucocorticoid;GO:0021543//pallium development;GO:0010038//response to metal ion gi|162461883|ref|NP_038849.2|/0/3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 6 [Mus musculus] 229499 1613 0.01 0.1 3.321928095 Up 0.236827259 Fcrl1 Fc receptor-like 1 K06727|1|0.0|639|mmu:229499|Fc receptor-like protein GO:0031224//intrinsic component of membrane - - "gi|148683413|gb|EDL15360.1|/1.50741e-171/Fc receptor-like 1, isoform CRA_d, partial [Mus musculus]" 20295 541 0.01 0.1 3.321928095 Up 0.236827259 Ccl17 chemokine (C-C motif) ligand 17 "K05514|1|2e-48|193|mmu:20295|C-C motif chemokine, other" GO:0044421 GO:0048020//CCR chemokine receptor binding;GO:0005125//cytokine activity GO:0006952//defense response;GO:0002376//immune system process;GO:0042221//response to chemical;GO:0007154//cell communication gi|5929762|gb|AAD56600.1|AF125570_1/2.88691e-51/CC chemokine ABCD-2 [Mus musculus] 432745 1033 0.01 0.103333333 3.36923381 Up 0.236827259 4930447K03Rik RIKEN cDNA 4930447K03 gene K07375|1|2e-12|75.9|mgp:100543297|tubulin beta - - - - 53814 955 0.01 0.1 3.321928095 Up 0.236827259 Oaz3 ornithine decarboxylase antizyme 3 K16614|1|6e-127|328|mmu:53814|ornithine decarboxylase antizyme 3 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0004857//enzyme inhibitor activity GO:0006576//cellular biogenic amine metabolic process;GO:0044092//negative regulation of molecular function gi|190844347|ref|NP_058597.2|/5.0077e-126/ornithine decarboxylase antizyme 3 [Mus musculus] 70138 550 0.01 0.1 3.321928095 Up 0.236827259 2210417A02Rik RIKEN cDNA 2210417A02 gene - - - - - 24111 538 0.1 0.01 -3.321928095 Down 0.236827259 Uts2 urotensin 2 K05248|1|3e-54|213|mmu:24111|urotensin 2 GO:0044421 GO:0005102//receptor binding "GO:0001525//angiogenesis;GO:0002027//regulation of heart rate;GO:0010840//regulation of circadian sleep/wake cycle, wakefulness;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010761//fibroblast migration;GO:0050796//regulation of insulin secretion;GO:0048545//response to steroid hormone;GO:0042311//vasodilation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0008284//positive regulation of cell proliferation;GO:0035809;GO:0030154//cell differentiation;GO:0035813//regulation of renal sodium excretion;GO:0003093//regulation of glomerular filtration;GO:0007271//synaptic transmission, cholinergic;GO:0042320//regulation of circadian sleep/wake cycle, REM sleep" gi|6755931|ref|NP_036040.1|/1.77057e-53/urotensin-2 precursor [Mus musculus] 381810 1393 0.01 0.103333333 3.36923381 Up 0.236827259 Lpar5 lysophosphatidic acid receptor 5 K08390|1|7e-159|562|mmu:381810|lysophosphatidic acid receptor 5 GO:0016020//membrane;GO:0016020//membrane GO:0004930//G-protein coupled receptor activity;GO:0004930//G-protein coupled receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway gi|253795528|ref|NP_001156740.1|/5.9382e-158/lysophosphatidic acid receptor 5 [Mus musculus] 105447647 518 0.01 0.103333333 3.36923381 Up 0.236827259 Munc MyoD upstream noncoding - - - - - 69384 538 0.01 0.103333333 3.36923381 Up 0.236827259 Tmem89 transmembrane protein 89 K10447|1|1e-11|71.2|shr:100929391|kelch-like protein 9/13 GO:0031224//intrinsic component of membrane - - gi|254553287|ref|NP_081342.1|/1.34316e-85/transmembrane protein 89 precursor [Mus musculus] 102637366 549 0.01 0.1 3.321928095 Up 0.236827259 Gm10037 predicted gene 10037 K09228|1|4e-29|129|mmu:328274|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0043169//cation binding;GO:0005515//protein binding;GO:0043169//cation binding - gi|823683755|ref|NP_001296303.1|/2.10111e-48/predicted gene 10037 [Mus musculus] 74703 1306 0.01 0.103333333 3.36923381 Up 0.236827259 Ccdc7a coiled-coil domain containing 7A K20478|1|2e-26|122|acs:100562086|golgin subfamily B member 1 - - - - 78520 1077 0.1 0.01 -3.321928095 Down 0.236827259 C330022C24Rik RIKEN cDNA C330022C24 gene K07127|1|9e-07|57.0|rno:293613|5-hydroxyisourate hydrolase [EC:3.5.2.17] - - - - 13035 1015 0.1 0.01 -3.321928095 Down 0.236827259 Ctsg cathepsin G K01319|1|5e-142|506|mmu:13035|cathepsin G [EC:3.4.21.20];K09616|5|4e-94|347|aml:100484190|granzyme H (cathepsin G-like 2) [EC:3.4.21.-] - - - - 66402 536 0.01 0.103333333 3.36923381 Up 0.236827259 Sln sarcolipin - - - - gi|803339362|ref|XP_012027737.1|/1.06358e-10/PREDICTED: sarcolipin isoform X2 [Ovis aries musimon] 58802 1032 0.103333333 0.01 -3.36923381 Down 0.236827259 Kcnmb4 "potassium large conductance calcium-activated channel, subfamily M, beta member 4" K04941|1|3e-113|410|mmu:58802|potassium large conductance calcium-activated channel subfamily M beta member 4 GO:0005887//integral component of plasma membrane GO:0005488//binding;GO:0005227//calcium activated cation channel activity GO:0001508//action potential;GO:0009593//detection of chemical stimulus;GO:0007269//neurotransmitter secretion;GO:0042310//vasoconstriction;GO:0007599//hemostasis;GO:0030001//metal ion transport gi|10946834|ref|NP_067427.1|/2.40976e-112/calcium-activated potassium channel subunit beta-4 [Mus musculus] 330440 1475 0.01 0.1 3.321928095 Up 0.236827259 Gm766 "sulfotransferase family 6B, member 2" K01025|1|9e-48|193|ngi:103731112|;K01016|3|3e-47|192|pss:102444463|estrone sulfotransferase [EC:2.8.2.4] - - - gi|223972623|ref|NP_001138862.1|/1.99804e-167/uncharacterized protein LOC330440 [Mus musculus] 20974 1959 0.01 0.103333333 3.36923381 Up 0.236827259 Syngr3 synaptogyrin 3 K17783|1|1e-69|266|shr:100917660|mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2];K04403|2|6e-26|121|gfr:102037151|TAK1-binding protein 1 GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic component of membrane;GO:0045202//synapse GO:0019904//protein domain specific binding GO:0032409 gi|31560541|ref|NP_035652.2|/5.93097e-104/synaptogyrin-3 [Mus musculus] 27399 4429 16.99666667 15.88333333 -0.097738124 Down 0.236780247 Ip6k1 inositol hexaphosphate kinase 1 K07756|1|0.0|814|mmu:27399|inositol-hexakisphosphate 5-kinase [EC:2.7.4.21] GO:0031981//nuclear lumen GO:0051766//inositol trisphosphate kinase activity;GO:0032550;GO:0000828//inositol hexakisphosphate kinase activity GO:0046488//phosphatidylinositol metabolic process gi|50510427|dbj|BAD32199.1|/0/mKIAA0263 protein [Mus musculus] 73316 1447.9 15.57333333 16.68 0.099041515 Up 0.236780247 Calr3 calreticulin 3 K10098|1|0.0|728|mmu:73316|calreticulin 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0044267//cellular protein metabolic process;GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|41462328|ref|NP_084058.2|/8.47497e-141/calreticulin-3 isoform 2 [Mus musculus] 67723 4135 0.93 1.18 0.343484238 Up 0.23675204 Cep83os "centrosomal protein 83, opposite strand" - - - - - 69263 1215 3.853333333 3.423333333 -0.170705216 Down 0.236686224 Rfc3 replication factor C (activator 1) 3 K10756|1|0.0|711|mmu:69263|replication factor C subunit 3/5 GO:0031981//nuclear lumen;GO:0005657//replication fork GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0003677//DNA binding GO:0006261//DNA-dependent DNA replication;GO:0010033//response to organic substance;GO:0051320;GO:0006289//nucleotide-excision repair;GO:0000723//telomere maintenance;GO:0009154//purine ribonucleotide catabolic process gi|124249204|ref|NP_081285.1|/0/replication factor C subunit 3 [Mus musculus] 66589 1956.23 105.2733333 111.4033333 0.081652365 Up 0.236667419 Ube2v1 ubiquitin-conjugating enzyme E2 variant 1 K10704|1|1e-70|270|rno:296390|ubiquitin-conjugating enzyme E2 variant GO:0043231//intracellular membrane-bounded organelle;GO:0031371//ubiquitin conjugating enzyme complex;GO:0044444//cytoplasmic part "GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0005488//binding" GO:0000209//protein polyubiquitination;GO:0002753;GO:0050851//antigen receptor-mediated signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002224//toll-like receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0048869//cellular developmental process;GO:0006301//postreplication repair gi|902763303|ref|NP_001298060.1|/1.5756e-86/ubiquitin-conjugating enzyme E2 variant 1 isoform 1 [Mus musculus] 15007 1473 0.323333333 0.166666667 -0.956056652 Down 0.236648614 H2-Q10 "histocompatibility 2, Q region locus 10" "K06751|1|1e-180|635|mmu:15007|major histocompatibility complex, class I" GO:0031224//intrinsic component of membrane;GO:0042611;GO:0009986//cell surface GO:0046983//protein dimerization activity;GO:0033218//amide binding GO:0002484;GO:0002462//tolerance induction to nonself antigen;GO:0002664//regulation of T cell tolerance induction;GO:0009581;GO:0001817//regulation of cytokine production;GO:0001911 "gi|6754132|ref|NP_034521.1|/1.02141e-179/H-2 class I histocompatibility antigen, Q10 alpha chain precursor [Mus musculus]" 19662 930 0.32 0.163333333 -0.970252657 Down 0.236648614 Rbp4 "retinol binding protein 4, plasma" K18271|1|5e-107|389|mmu:19662|retinol-binding protein 4 GO:0032991//macromolecular complex;GO:0044421;GO:0032991//macromolecular complex;GO:0044421 GO:0005501//retinoid binding;GO:0046983//protein dimerization activity;GO:0005319//lipid transporter activity;GO:0005501//retinoid binding;GO:0046983//protein dimerization activity;GO:0005319//lipid transporter activity GO:0001501//skeletal system development;GO:0003206//cardiac chamber morphogenesis;GO:0001523//retinoid metabolic process;GO:0033500//carbohydrate homeostasis;GO:0043010//camera-type eye development;GO:0008406//gonad development;GO:0050796//regulation of insulin secretion;GO:0048305//immunoglobulin secretion;GO:0008285//negative regulation of cell proliferation;GO:0043434//response to peptide hormone;GO:0010669//epithelial structure maintenance;GO:0007601//visual perception;GO:0006006//glucose metabolic process;GO:0030323//respiratory tube development;GO:0030540//female genitalia development;GO:0048232//male gamete generation;GO:0097305//response to alcohol;GO:0033993//response to lipid;GO:0048598//embryonic morphogenesis;GO:0046865//terpenoid transport;GO:0001501//skeletal system development;GO:0003206//cardiac chamber morphogenesis;GO:0001523//retinoid metabolic process;GO:0033500//carbohydrate homeostasis;GO:0043010//camera-type eye development;GO:0008406//gonad development;GO:0050796//regulation of insulin secretion;GO:0048305//immunoglobulin secretion;GO:0008285//negative regulation of cell proliferation;GO:0043434//response to peptide hormone;GO:0010669//epithelial structure maintenance;GO:0007601//visual perception;GO:0006006//glucose metabolic process;GO:0030323//respiratory tube development;GO:0030540//female genitalia development;GO:0048232//male gamete generation;GO:0097305//response to alcohol;GO:0033993//response to lipid;GO:0048598//embryonic morphogenesis;GO:0046865//terpenoid transport gi|226958688|ref|NP_001152959.1|/6.6668e-134/retinol-binding protein 4 isoform 1 [Mus musculus] 26939 4234 3.096666667 3.506666667 0.179384203 Up 0.236620407 Polr3e polymerase (RNA) III (DNA directed) polypeptide E K14721|1|0.0|1318|mmu:26939|DNA-directed RNA polymerase III subunit RPC5 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0034062//RNA polymerase activity;GO:0034062//RNA polymerase activity GO:0006952//defense response;GO:0002252;GO:0010467//gene expression;GO:0006952//defense response;GO:0002252;GO:0010467//gene expression gi|31981264|ref|NP_079574.2|/0/DNA-directed RNA polymerase III subunit RPC5 isoform 1 [Mus musculus] 235134 5181 3.46 3.05 -0.181962795 Down 0.236620407 Nfrkb nuclear factor related to kappa B binding protein K11671|1|0.0|2051|mmu:235134|nuclear factor related to kappa-B-binding protein GO:0000790//nuclear chromatin GO:0003676//nucleic acid binding "GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006351//transcription, DNA-templated" "gi|148693396|gb|EDL25343.1|/0/nuclear factor related to kappa B binding protein, isoform CRA_a, partial [Mus musculus]" 100041585 3201 0.643333333 0.443333333 -0.537174602 Down 0.2365922 Amd2 S-adenosylmethionine decarboxylase 2 K01611|1|7e-180|634|mmu:11702|S-adenosylmethionine decarboxylase [EC:4.1.1.50] - GO:0005488//binding;GO:0016831//carboxy-lyase activity GO:0006596//polyamine biosynthetic process;GO:0044272//sulfur compound biosynthetic process gi|168229240|ref|NP_031470.3|/5.34313e-180/S-adenosylmethionine decarboxylase proenzyme 2 [Mus musculus] 171580 3411.5 6.506666667 7.116666667 0.129283017 Up 0.236582797 Mical1 "microtubule associated monooxygenase, calponin and LIM domain containing 1" K19947|1|0.0|1585|mmu:171580|protein-methionine sulfoxide oxidase MICAL [EC:1.14.13.-] GO:0043232 GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0004497//monooxygenase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0019904//protein domain specific binding GO:0001932//regulation of protein phosphorylation;GO:0044710;GO:0006915//apoptotic process;GO:0008154//actin polymerization or depolymerization "gi|148673025|gb|EDL04972.1|/0/microtubule associated monoxygenase, calponin and LIM domain containing 1, isoform CRA_a, partial [Mus musculus]" 192662 2732 98.62666667 104.5566667 0.084235373 Up 0.236526383 Arhgdia Rho GDP dissociation inhibitor (GDI) alpha K12462|1|8e-116|417|tup:102490136|Rho GDP-dissociation inhibitor GO:0044459;GO:0044424 GO:0008047//enzyme activator activity;GO:0005488//binding;GO:0005092//GDP-dissociation inhibitor activity GO:0019222//regulation of metabolic process;GO:0008104//protein localization;GO:0007265//Ras protein signal transduction gi|676282170|gb|KFO35713.1|/1.55748e-116/Rho GDP-dissociation inhibitor 1 [Fukomys damarensis] 54194 2097 26.44 28.23333333 0.094677292 Up 0.236516981 Akap8l A kinase (PRKA) anchor protein 8-like K15978|1|0.0|860|mmu:54194|A-kinase anchor protein 8-like protein GO:0034399//nuclear periphery GO:0046872//metal ion binding - gi|12847376|dbj|BAB27546.1|/0/unnamed protein product [Mus musculus] 432812 1642 0.063333333 0.196666667 1.634715536 Up 0.236507578 BC052688 cDNA sequence BC052688 K09228|1|2e-105|248|mmu:105245687|KRAB domain-containing zinc finger protein - - - gi|755485546|ref|XP_011243468.1|/2.01706e-104/PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC105245687 [Mus musculus] 243270 3285 0.196666667 0.063333333 -1.634715536 Down 0.236507578 Hcar1 hydrocarboxylic acid receptor 1 K08401|1|0.0|647|mmu:243270|G protein-coupled receptor 81 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0043627//response to estrogen;GO:0007166//cell surface receptor signaling pathway gi|259490314|ref|NP_780729.2|/0/hydroxycarboxylic acid receptor 1 [Mus musculus] 76917 688 0.376666667 0.57 0.597673552 Up 0.236488774 Flywch2 FLYWCH family member 2 - - - - gi|21553307|ref|NP_084074.1|/2.13754e-63/FLYWCH family member 2 [Mus musculus] 791260 1354 0.37 0.56 0.597901556 Up 0.236488774 Tomt transmembrane O-methyltransferase K00545|1|7e-44|180|mdo:100031097|catechol O-methyltransferase [EC:2.1.1.6] GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424 GO:0008171//O-methyltransferase activity;GO:0008171//O-methyltransferase activity GO:0050954//sensory perception of mechanical stimulus;GO:0042133//neurotransmitter metabolic process;GO:0042491//auditory receptor cell differentiation;GO:0006584//catecholamine metabolic process;GO:0050954//sensory perception of mechanical stimulus;GO:0042133//neurotransmitter metabolic process;GO:0042491//auditory receptor cell differentiation;GO:0006584//catecholamine metabolic process gi|126157494|ref|NP_001075148.1|/1.78353e-143/transmembrane O-methyltransferase [Mus musculus] 212862 1915.33 100.2333333 106.06 0.081518286 Up 0.236385347 Chpt1 choline phosphotransferase 1 K00994|1|0.0|730|mmu:212862|diacylglycerol cholinephosphotransferase [EC:2.7.8.2] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0017169//CDP-alcohol phosphatidyltransferase activity;GO:0043169//cation binding;GO:0017169//CDP-alcohol phosphatidyltransferase activity;GO:0043169//cation binding;GO:0017169//CDP-alcohol phosphatidyltransferase activity GO:0006644//phospholipid metabolic process;GO:0046165;GO:0006644//phospholipid metabolic process;GO:0046165;GO:0006644//phospholipid metabolic process;GO:0046165 gi|226442811|ref|NP_659056.3|/0/cholinephosphotransferase 1 isoform 2 [Mus musculus] 57874 2738 8.006666667 8.706666667 0.120918746 Up 0.236338335 Hacd3 3-hydroxyacyl-CoA dehydratase 3 K10703|1|0.0|669|mmu:57874|very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134] - - - - 14270 8040 4.036666667 4.5 0.156760542 Up 0.236328933 Srgap2 SLIT-ROBO Rho GTPase activating protein 2 K07526|1|0.0|2057|mmu:14270|SLIT-ROBO Rho GTPase activating protein GO:0030139//endocytic vesicle;GO:0031252//cell leading edge;GO:0019866//organelle inner membrane;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane GO:0017048//Rho GTPase binding;GO:0042802//identical protein binding GO:0021815;GO:0030031//cell projection assembly;GO:0016358//dendrite development;GO:0001667//ameboidal-type cell migration;GO:0030029//actin filament-based process;GO:0000904//cell morphogenesis involved in differentiation;GO:0006935//chemotaxis;GO:0008219//cell death;GO:0001764//neuron migration gi|157951723|ref|NP_001074480.2|/0/SLIT-ROBO Rho GTPase-activating protein 2 [Mus musculus] 22365 2643 3.876666667 4.336666667 0.161769865 Up 0.236328933 Vps45 vacuolar protein sorting 45 K12479|1|0.0|1089|mmu:22365|vacuolar protein sorting-associated protein 45 GO:0012505//endomembrane system;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0007599//hemostasis;GO:0006887//exocytosis;GO:0015031//protein transport gi|7305631|ref|NP_038869.1|/0/vacuolar protein sorting-associated protein 45 [Mus musculus] 11488 5133 4.333333333 3.87 -0.163143651 Down 0.236328933 Adam11 a disintegrin and metallopeptidase domain 11 K16067|1|0.0|1539|mmu:11488|disintegrin and metalloproteinase domain-containing protein 11 [EC:3.4.24.-] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway gi|160707883|ref|NP_033743.2|/0/disintegrin and metalloproteinase domain-containing protein 11 isoform 2 precursor [Mus musculus] 22722 2770 3.85 4.31 0.162829424 Up 0.236328933 Zfp64 zinc finger protein 64 K19871|1|0.0|883|mgp:100541682|sal-like protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|148276996|ref|NP_033590.2|/0/zinc finger protein 64 [Mus musculus] 436230 3243 0.24 0.1 -1.263034406 Down 0.236244312 BC065397 cDNA sequence BC065397 K07945|1|2e-31|140|ggo:101151990|ADP-ribosylation factor-like protein 4 - - - - 68441 1653 27.28 29.05333333 0.090860051 Up 0.236244312 Rraga Ras-related GTP binding A K16185|1|9e-178|625|myb:102258827|Ras-related GTP-binding protein A/B GO:0000323//lytic vacuole GO:0032550;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity GO:0009967//positive regulation of signal transduction;GO:0019835//cytolysis;GO:0012501//programmed cell death;GO:0043200//response to amino acid;GO:0008104//protein localization "gi|22902383|gb|AAH37615.1|/0/Rraga protein, partial [Mus musculus]" 319772 2006 0.103333333 0.246666667 1.255257055 Up 0.236244312 C130050O18Rik RIKEN cDNA C130050O18 gene K08431|1|4e-13|79.0|myb:102252956|G protein-coupled receptor 146;K04246|3|8e-08|48.1|bacu:103004209|G protein-coupled receptor 30 - - - gi|568938733|ref|XP_006504772.1|/0/PREDICTED: uncharacterized protein LOC319772 isoform X2 [Mus musculus] 224897 3509 29.27333333 27.50666667 -0.089805713 Down 0.236244312 Dpp9 dipeptidylpeptidase 9 K08656|1|0.0|1694|mmu:224897|dipeptidyl-peptidase 9 [EC:3.4.14.5] GO:0044424 GO:0008238//exopeptidase activity GO:0019538//protein metabolic process gi|569000041|ref|XP_006524217.1|/0/PREDICTED: dipeptidyl peptidase 9 isoform X2 [Mus musculus] 242691 2003 2.513333333 2.88 0.196466789 Up 0.236244312 Gpatch3 G patch domain containing 3 - - GO:0097159//organic cyclic compound binding - gi|27370332|ref|NP_766464.1|/0/G patch domain-containing protein 3 [Mus musculus] 18196 2140 2.496666667 2.866666667 0.199370941 Up 0.236244312 Nsg1 neuron specific gene family member 1 K15493|1|3e-15|86.3|rro:104677643|neuron-specific vesicular protein calcyon GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0001664//G-protein coupled receptor binding;GO:0030276//clathrin binding GO:0006901//vesicle coating;GO:0007186//G-protein coupled receptor signaling pathway gi|31543351|ref|NP_035072.2|/6.02962e-81/neuron-specific protein family member 1 [Mus musculus] 235907 3960 2.426666667 2.796666667 0.20473236 Up 0.236244312 Zfp65 zinc finger protein 65 K09228|1|0.0|805|mmu:235907|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - "gi|21704250|ref|NP_663597.1|/0/zinc finger protein 71, related sequence [Mus musculus]" 319960 2803 0.173333333 0.333333333 0.943416472 Up 0.2361973 4930513N10Rik RIKEN cDNA 4930513N10 gene - - - - - 94088 3827 0.333333333 0.173333333 -0.943416472 Down 0.2361973 Trim6 tripartite motif-containing 6 K11999|1|0.0|947|mmu:94088|tripartite motif-containing protein 6/22/34 GO:0044424 GO:0046914//transition metal ion binding GO:0051259//protein oligomerization gi|61966933|ref|NP_001013637.1|/0/tripartite motif-containing protein 6 [Mus musculus] 71799 3219 15.89333333 14.80666667 -0.102174843 Down 0.236178495 Ptcd1 pentatricopeptide repeat domain 1 K17710|1|0.0|1306|mmu:71799|pentatricopeptide repeat domain-containing protein 1 GO:0044429 - GO:0008033//tRNA processing "gi|254588125|ref|NP_598496.3|/0/pentatricopeptide repeat-containing protein 1, mitochondrial [Mus musculus]" 14264 2859 0.38 0.57 0.584962501 Up 0.23615969 Fmod fibromodulin K08121|1|0.0|649|mmu:14264|fibromodulin GO:0044464;GO:0044421;GO:0031012//extracellular matrix - GO:0009611//response to wounding;GO:0009887//organ morphogenesis "gi|30851675|gb|AAH52673.1|/0/Fmod protein, partial [Mus musculus]" 66752 3985 0.386666667 0.58 0.584962501 Up 0.23615969 4933404O12Rik RIKEN cDNA 4933404O12 gene - - - - - 11750 2861.53 28.76666667 30.52333333 0.085514463 Up 0.236103276 Anxa7 annexin A7 K17095|1|0.0|664|mmu:11750|annexin A7/11 GO:0030667//secretory granule membrane;GO:0030667//secretory granule membrane GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0005515//protein binding GO:0050878//regulation of body fluid levels;GO:0010038//response to metal ion;GO:0022604//regulation of cell morphogenesis;GO:0006875//cellular metal ion homeostasis;GO:0006970//response to osmotic stress;GO:0051705;GO:0010033//response to organic substance;GO:0006884//cell volume homeostasis;GO:0050878//regulation of body fluid levels;GO:0010038//response to metal ion;GO:0022604//regulation of cell morphogenesis;GO:0006875//cellular metal ion homeostasis;GO:0006970//response to osmotic stress;GO:0051705;GO:0010033//response to organic substance;GO:0006884//cell volume homeostasis "gi|148669563|gb|EDL01510.1|/0/annexin A7, isoform CRA_a, partial [Mus musculus]" 76205 1362 4.473333333 4.963333333 0.149959082 Up 0.236046861 Stard3nl STARD3 N-terminal like - GO:0031224//intrinsic component of membrane;GO:0005770//late endosome - - gi|537212825|gb|ERE80831.1|/1.10644e-108/putative MLN64 domain like protein [Cricetulus griseus] 50868 3400.16 25.94 27.69 0.094186574 Up 0.236028057 Keap1 kelch-like ECH-associated protein 1 K10456|1|0.0|1291|mmu:50868|kelch-like protein 19 GO:0031981//nuclear lumen;GO:0005911//cell-cell junction;GO:0005815//microtubule organizing center;GO:0005924//cell-substrate adherens junction;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031981//nuclear lumen;GO:0005911//cell-cell junction;GO:0005815//microtubule organizing center;GO:0005924//cell-substrate adherens junction;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031981//nuclear lumen;GO:0005911//cell-cell junction;GO:0005815//microtubule organizing center;GO:0005924//cell-substrate adherens junction;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031981//nuclear lumen;GO:0005911//cell-cell junction;GO:0005815//microtubule organizing center;GO:0005924//cell-substrate adherens junction;GO:0031461//cullin-RING ubiquitin ligase complex GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding "GO:0006351//transcription, DNA-templated;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0043648//dicarboxylic acid metabolic process;GO:0006461//protein complex assembly;GO:0010498//proteasomal protein catabolic process;GO:0009913//epidermal cell differentiation;GO:0009698//phenylpropanoid metabolic process;GO:0043009//chordate embryonic development;GO:0014070//response to organic cyclic compound;GO:0006790//sulfur compound metabolic process;GO:0010035//response to inorganic substance;GO:0032446//protein modification by small protein conjugation;GO:0006950//response to stress;GO:0070670//response to interleukin-4;GO:0009725//response to hormone;GO:0006351//transcription, DNA-templated;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0043648//dicarboxylic acid metabolic process;GO:0006461//protein complex assembly;GO:0010498//proteasomal protein catabolic process;GO:0009913//epidermal cell differentiation;GO:0009698//phenylpropanoid metabolic process;GO:0043009//chordate embryonic development;GO:0014070//response to organic cyclic compound;GO:0006790//sulfur compound metabolic process;GO:0010035//response to inorganic substance;GO:0032446//protein modification by small protein conjugation;GO:0006950//response to stress;GO:0070670//response to interleukin-4;GO:0009725//response to hormone;GO:0006351//transcription, DNA-templated;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0043648//dicarboxylic acid metabolic process;GO:0006461//protein complex assembly;GO:0010498//proteasomal protein catabolic process;GO:0009913//epidermal cell differentiation;GO:0009698//phenylpropanoid metabolic process;GO:0043009//chordate embryonic development;GO:0014070//response to organic cyclic compound;GO:0006790//sulfur compound metabolic process;GO:0010035//response to inorganic substance;GO:0032446//protein modification by small protein conjugation;GO:0006950//response to stress;GO:0070670//response to interleukin-4;GO:0009725//response to hormone;GO:0006351//transcription, DNA-templated;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0043648//dicarboxylic acid metabolic process;GO:0006461//protein complex assembly;GO:0010498//proteasomal protein catabolic process;GO:0009913//epidermal cell differentiation;GO:0009698//phenylpropanoid metabolic process;GO:0043009//chordate embryonic development;GO:0014070//response to organic cyclic compound;GO:0006790//sulfur compound metabolic process;GO:0010035//response to inorganic substance;GO:0032446//protein modification by small protein conjugation;GO:0006950//response to stress;GO:0070670//response to interleukin-4;GO:0009725//response to hormone" gi|37359786|dbj|BAC97871.1|/0/mKIAA0132 protein [Mus musculus] 223255 2575 28.88333333 27.14333333 -0.089639347 Down 0.235934033 Stk24 serine/threonine kinase 24 K08838|1|0.0|750|mmu:223255|serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0032550;GO:0004672//protein kinase activity;GO:0043169//cation binding GO:0022411;GO:0007154//cell communication;GO:0031103//axon regeneration;GO:0006468//protein phosphorylation;GO:0012502//induction of programmed cell death;GO:0016477//cell migration;GO:0006979//response to oxidative stress gi|21703922|ref|NP_663440.1|/0/serine/threonine-protein kinase 24 [Mus musculus] 26404 5367.77 25.6 27.33666667 0.094693526 Up 0.235934033 Map3k12 mitogen-activated protein kinase kinase kinase 12 K04423|1|0.0|1359|mmu:26404|mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25] GO:0016020//membrane;GO:0030424//axon;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0030424//axon;GO:0044444//cytoplasmic part GO:0004674//protein serine/threonine kinase activity;GO:0042802//identical protein binding;GO:0019900//kinase binding;GO:0004674//protein serine/threonine kinase activity;GO:0042802//identical protein binding;GO:0019900//kinase binding GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade "gi|148672025|gb|EDL03972.1|/0/mitogen activated protein kinase kinase kinase 12, isoform CRA_b, partial [Mus musculus]" 53602 1561 26.07666667 27.81333333 0.093017193 Up 0.235934033 Hpcal1 hippocalcin-like 1 K19695|1|2e-99|365|cjo:107310436|neurocalcin delta - GO:0046872//metal ion binding - gi|444731687|gb|ELW72036.1|/1.32483e-108/Hippocalcin-like protein 1 [Tupaia chinensis] 67181 1615 94.82 100.1366667 0.078707039 Up 0.235858814 Ctdnep1 CTD nuclear envelope phosphatase 1 K17617|1|2e-136|488|ptr:455234|CTD nuclear envelope phosphatase 1 [EC:3.1.3.16] GO:0031224//intrinsic component of membrane;GO:0008287//protein serine/threonine phosphatase complex;GO:0031090//organelle membrane;GO:0005635//nuclear envelope GO:0005488//binding;GO:0004721//phosphoprotein phosphatase activity GO:0010866//regulation of triglyceride biosynthetic process;GO:0006464//cellular protein modification process;GO:0033365//protein localization to organelle;GO:0006997//nucleus organization gi|694965848|ref|XP_511976.4|/1.33628e-135/PREDICTED: CTD nuclear envelope phosphatase 1 [Pan troglodytes] 232943 1820 0.87 1.113333333 0.355798296 Up 0.235849411 Klc3 kinesin light chain 3 K10407|1|0.0|712|mmu:232943|kinesin light chain GO:0005875//microtubule associated complex;GO:0005929//cilium;GO:0005875//microtubule associated complex;GO:0005929//cilium;GO:0005875//microtubule associated complex;GO:0005929//cilium GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0003774//motor activity;GO:0015631//tubulin binding GO:0010970//transport along microtubule;GO:0010970//transport along microtubule;GO:0010970//transport along microtubule "gi|148691194|gb|EDL23141.1|/0/kinesin light chain 3, isoform CRA_a, partial [Mus musculus]" 17763 1635 0.46 0.663333333 0.528100164 Up 0.235811802 Mtcp1 mature T cell proliferation 1 K16837|1|3e-52|208|mmu:17763|mature T-cell proliferation-1 type B1 GO:0043231//intracellular membrane-bounded organelle - GO:0044699 gi|86439951|ref|NP_001034462.1|/2.71007e-51/protein p13 MTCP-1 [Mus musculus] 12301 2115 15.62333333 16.70333333 0.096433743 Up 0.235802399 Cacybp calcyclin binding protein K04507|1|4e-126|454|mmu:12301|calcyclin binding protein GO:0043234//protein complex;GO:0042995//cell projection;GO:0005635//nuclear envelope GO:0042802//identical protein binding GO:0035051//cardiocyte differentiation;GO:0008219//cell death;GO:0006260//DNA replication;GO:0043434//response to peptide hormone;GO:0051592//response to calcium ion gi|3142331|gb|AAC16757.1|/9.33684e-135/calcyclin binding protein [Mus musculus] 94178 2039 16.01 14.93333333 -0.100437076 Down 0.235802399 Mcoln1 mucolipin 1 K04992|1|0.0|1158|mmu:94178|mucolipin 1 GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0005770//late endosome - GO:0051283//negative regulation of sequestering of calcium ion;GO:0070838//divalent metal ion transport gi|16716463|ref|NP_444407.1|/0/mucolipin-1 [Mus musculus] 320633 5290 0.33 0.173333333 -0.928916902 Down 0.23576479 Zbtb26 zinc finger and BTB domain containing 26 K10505|1|0.0|886|rno:311910|zinc finger and BTB domain-containing protein 26 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - gi|50510995|dbj|BAD32483.1|/0/mKIAA1572 protein [Mus musculus] 30937 1742 29.72666667 28.01 -0.085815716 Down 0.23572718 Lmcd1 LIM and cysteine-rich domains 1 K04511|1|4e-55|218|bfo:BRAFLDRAFT_121177|prickle GO:0043231//intracellular membrane-bounded organelle;GO:0044421 GO:0003712//transcription cofactor activity;GO:0046914//transition metal ion binding GO:0003300//cardiac muscle hypertrophy;GO:0033173//calcineurin-NFAT signaling cascade;GO:0006366//transcription from RNA polymerase II promoter gi|21450157|ref|NP_659048.1|/0/LIM and cysteine-rich domains protein 1 [Mus musculus] 16211 5909 28.56 26.84 -0.089611308 Down 0.23572718 Kpnb1 karyopherin (importin) beta 1 K14293|1|0.0|1681|chx:102173035|importin subunit beta-1 GO:0005635//nuclear envelope;GO:0032991//macromolecular complex GO:0005515//protein binding;GO:0022892//substrate-specific transporter activity GO:0006606//protein import into nucleus gi|926717140|ref|XP_005693775.2|/0/PREDICTED: importin subunit beta-1 [Capra hircus] 22123 2167 86.11666667 91.30333333 0.084375054 Up 0.235689571 Psmd3 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 3" K03033|1|0.0|885|rno:287670|26S proteasome regulatory subunit N3 GO:0000502//proteasome complex - GO:0009894 gi|56605666|ref|NP_001008282.1|/0/26S proteasome non-ATPase regulatory subunit 3 [Rattus norvegicus] 22142 1591 91.81333333 86.68 -0.083004527 Down 0.235595547 Tuba1a "tubulin, alpha 1A" K07374|1|0.0|859|dre:573216|tubulin alpha GO:0005874//microtubule;GO:0044444//cytoplasmic part GO:0005198//structural molecule activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0046983//protein dimerization activity GO:0007010//cytoskeleton organization;GO:0006458//'de novo' protein folding;GO:0044772//mitotic cell cycle phase transition;GO:0044765//single-organism transport;GO:0043623//cellular protein complex assembly;GO:0009154//purine ribonucleotide catabolic process gi|6755901|ref|NP_035783.1|/0/tubulin alpha-1A chain [Mus musculus] 53420 1764 0.306666667 0.49 0.676110389 Up 0.235586145 Syt5 synaptotagmin V K19905|1|0.0|654|mmu:53420|synaptotagmin-5 GO:0031224//intrinsic component of membrane;GO:0030141//secretory granule;GO:0044297//cell body;GO:0008021//synaptic vesicle;GO:0042995//cell projection;GO:0010008//endosome membrane GO:0043169//cation binding;GO:0000149//SNARE binding;GO:0005543//phospholipid binding;GO:0046983//protein dimerization activity GO:0006887//exocytosis gi|8394392|ref|NP_058604.1|/0/synaptotagmin-5 [Mus musculus] 209176 3014 0.033333333 0.15 2.169925001 Up 0.235586145 Ido2 "indoleamine 2,3-dioxygenase 2" "K00463|1|0.0|813|mmu:209176|indoleamine 2,3-dioxygenase [EC:1.13.11.52]" - "GO:0046906//tetrapyrrole binding;GO:0043169//cation binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" GO:0006569//tryptophan catabolic process "gi|347582671|ref|NP_666061.3|/0/indoleamine 2,3-dioxygenase 2 [Mus musculus]" 18414 4835 6.363333333 6.966666667 0.13068584 Up 0.235576742 Osmr oncostatin M receptor K05057|1|0.0|1929|mmu:18414|oncostatin M receptor GO:0005887//integral component of plasma membrane GO:0004896//cytokine receptor activity;GO:0005515//protein binding GO:0019221//cytokine-mediated signaling pathway;GO:0008283//cell proliferation "gi|148671404|gb|EDL03351.1|/0/oncostatin M receptor, isoform CRA_a, partial [Mus musculus]" 269823 1784 6.81 6.206666667 -0.133836131 Down 0.235576742 Pon3 paraoxonase 3 K01045|1|0.0|712|mmu:269823|arylesterase / paraoxonase [EC:3.1.1.2 3.1.8.1] GO:0043227//membrane-bounded organelle;GO:0044421 GO:0043169//cation binding;GO:0042802//identical protein binding;GO:0016791//phosphatase activity;GO:0052689//carboxylic ester hydrolase activity GO:0050896//response to stimulus;GO:0016054//organic acid catabolic process;GO:0009804//coumarin metabolic process;GO:0019439//aromatic compound catabolic process gi|27370510|ref|NP_766594.1|/0/serum paraoxonase/lactonase 3 precursor [Mus musculus] 269423 2492 11.20666667 10.37 -0.11194133 Down 0.23556734 Abhd18 abhydrolase domain containing 18 - - - - gi|167830469|ref|NP_080898.2|/0/protein ABHD18 precursor [Mus musculus] 23882 1081 10.19666667 11.03666667 0.114206904 Up 0.23556734 Gadd45g growth arrest and DNA-damage-inducible 45 gamma K04402|1|2e-87|324|mmu:23882|growth arrest and DNA-damage-inducible protein GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0042088//T-helper 1 type immune response;GO:0012501//programmed cell death;GO:0006259//DNA metabolic process;GO:0032147//activation of protein kinase activity;GO:0001933//negative regulation of protein phosphorylation;GO:0032609//interferon-gamma production;GO:0048869//cellular developmental process;GO:0007049//cell cycle gi|254553386|ref|NP_035947.2|/1.8724e-86/growth arrest and DNA damage-inducible protein GADD45 gamma [Mus musculus] 58243 1909 0.233333333 0.403333333 0.78958022 Up 0.235548535 Nap1l5 nucleosome assembly protein 1-like 5 K11283|1|6e-56|221|mmu:58243|nucleosome assembly protein 1-like 5 - - - - 170461 1496 0.53 0.74 0.481532911 Up 0.235548535 Stard6 StAR-related lipid transfer (START) domain containing 6 "K16931|1|1e-10|70.1|cmy:102929435|steroidogenic acute regulatory protein, mitochondrial" - GO:0005488//binding;GO:0015248//sterol transporter activity;GO:0005488//binding;GO:0015248//sterol transporter activity;GO:0005488//binding;GO:0015248//sterol transporter activity;GO:0005488//binding;GO:0015248//sterol transporter activity GO:0015918//sterol transport;GO:0008202//steroid metabolic process;GO:0015918//sterol transport;GO:0008202//steroid metabolic process;GO:0015918//sterol transport;GO:0008202//steroid metabolic process;GO:0015918//sterol transport;GO:0008202//steroid metabolic process gi|21312812|ref|NP_083295.1|/3.23299e-111/stAR-related lipid transfer protein 6 [Mus musculus] 22151 1638 27.33666667 29.04333333 0.087369706 Up 0.235539133 Tubb2a "tubulin, beta 2A class IIA" K07375|1|0.0|832|oaa:100079040|tubulin beta GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0015630//microtubule cytoskeleton GO:0005198//structural molecule activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0006458//'de novo' protein folding;GO:0043623//cellular protein complex assembly;GO:0009154//purine ribonucleotide catabolic process;GO:0016477//cell migration gi|586480181|ref|XP_006870616.1|/0/PREDICTED: tubulin beta-2A chain-like isoform X2 [Chrysochloris asiatica] 239393 4064 0.993333333 0.76 -0.386278506 Down 0.235539133 Lrp12 low density lipoprotein-related protein 12 K20050|1|0.0|1668|mmu:239393|low-density lipoprotein receptor-related protein 3/10/12 - - - gi|27370214|ref|NP_766402.1|/0/low-density lipoprotein receptor-related protein 12 precursor [Mus musculus] 226162 1353 7.966666667 8.653333333 0.119279765 Up 0.235510926 Dpcd deleted in primary ciliary dyskinesia K07380|1|1e-27|127|hro:HELRODRAFT_192677|contactin associated protein-like 2 - - GO:0003002//regionalization;GO:0048870//cell motility;GO:0021591//ventricular system development;GO:0003341//cilium movement;GO:0048232//male gamete generation;GO:0021537//telencephalon development;GO:0009855//determination of bilateral symmetry gi|31541998|ref|NP_766227.1|/6.18705e-112/protein DPCD [Mus musculus] 24070 1328 8.66 7.966666667 -0.120390813 Down 0.235510926 Mpdu1 mannose-P-dolichol utilization defect 1 K09660|1|7e-89|187|rno:303244|mannose-P-dolichol utilization defect 1 GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:1901137//carbohydrate derivative biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0051234//establishment of localization;GO:0009311//oligosaccharide metabolic process;GO:0051234//establishment of localization;GO:1901137//carbohydrate derivative biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0051234//establishment of localization;GO:1901137//carbohydrate derivative biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0009311//oligosaccharide metabolic process gi|31981340|ref|NP_036030.2|/1.56856e-107/mannose-P-dolichol utilization defect 1 protein isoform 1 [Mus musculus] 20563 9915 0.236666667 0.1 -1.242856524 Down 0.235473316 Slit2 slit homolog 2 (Drosophila) K06839|1|0.0|1639|mmu:20563|slit 2 - - - - 18127 4140 14.29 15.35666667 0.103859181 Up 0.235435706 Nos3 "nitric oxide synthase 3, endothelial cell" "K13242|1|0.0|2189|mmu:18127|nitric-oxide synthase, endothelial [EC:1.14.13.39]" - - - "gi|161086988|ref|NP_032739.3|/0/nitric oxide synthase, endothelial [Mus musculus]" 653030 2731 0.036666667 0.153333333 2.064130337 Up 0.235351085 Arhgap27os3 "Rho GTPase activating protein 27, opposite strand 3" - - - - - 19058 2829 24.93666667 26.63 0.094783798 Up 0.235313475 Ppp3r1 "protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)" K06268|1|2e-92|343|oaa:100083665|serine/threonine-protein phosphatase 2B regulatory subunit GO:0008287//protein serine/threonine phosphatase complex;GO:0044444//cytoplasmic part GO:0046872//metal ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding GO:0012501//programmed cell death;GO:0042991//transcription factor import into nucleus;GO:0006464//cellular protein modification process;GO:0030855//epithelial cell differentiation;GO:0000904//cell morphogenesis involved in differentiation "gi|966647643|gb|KTF82553.1|/4.75587e-92/hypothetical protein cypCar_00025180, partial [Cyprinus carpio]" 67207 2360 2.27 2.623333333 0.208708837 Up 0.235304073 Lsm1 "LSM1 homolog, mRNA degradation associated" K12620|1|1e-67|260|mmu:67207|U6 snRNA-associated Sm-like protein LSm1 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex GO:0003676//nucleic acid binding "GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0008380//RNA splicing" gi|110625667|ref|NP_080308.1|/1.24711e-66/U6 snRNA-associated Sm-like protein LSm1 [Mus musculus] 216858 2740 2.236666667 2.583333333 0.207883544 Up 0.235304073 Kctd11 potassium channel tetramerisation domain containing 11 "K03849|1|5e-24|115|cmk:103177229|alpha-1,3-glucosyltransferase [EC:2.4.1.265];K00849|2|1e-14|85.1|tru:101062137|galactokinase [EC:2.7.1.6];K20131|3|4e-13|79.7|pale:102883240|Rab5 GDP/GTP exchange factor" - - - - 108946 7581.41 2.263333333 2.61 0.205600733 Up 0.235304073 Zzz3 "zinc finger, ZZ domain containing 3" - GO:0000123//histone acetyltransferase complex GO:0046914//transition metal ion binding - "gi|148679974|gb|EDL11921.1|/0/zinc finger, ZZ domain containing 3, isoform CRA_b, partial [Mus musculus]" 241576 3908.15 2.59 2.24 -0.209453366 Down 0.235304073 Ldlrad3 low density lipoprotein receptor class A domain containing 3 K06233|1|2e-28|130|oas:101108200|low density lipoprotein-related protein 2 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0042277//peptide binding;GO:0042277//peptide binding GO:0016485//protein processing;GO:0006897//endocytosis;GO:0016485//protein processing;GO:0006897//endocytosis gi|26328037|dbj|BAC27759.1|/0/unnamed protein product [Mus musculus] 76630 1978 1.423333333 1.71 0.264722756 Up 0.235228854 Stambpl1 STAM binding protein like 1 K11867|1|0.0|842|mmu:76630|AMSH-like protease [EC:3.4.19.12] - "GO:0043169//cation binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process gi|55742879|ref|NP_083958.3|/0/AMSH-like protease [Mus musculus] 271842 5135 1.46 1.746666667 0.258635942 Up 0.235228854 Rpusd2 RNA pseudouridylate synthase domain containing 2 K01855|1|4e-10|70.9|mgp:100543853|tRNA pseudouridine38/39 synthase [EC:5.4.99.45] - GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity GO:0016070//RNA metabolic process gi|27734094|ref|NP_775626.1|/0/RNA pseudouridylate synthase domain-containing protein 2 [Mus musculus] 67118 2979.9 15.58 16.64333333 0.095249173 Up 0.235191244 Bfar bifunctional apoptosis regulator K15684|1|2e-157|559|shr:100915921|bifunctional apoptosis regulator GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0006915//apoptotic process;GO:0006915//apoptotic process "gi|148664950|gb|EDK97366.1|/0/mCG129801, isoform CRA_b [Mus musculus]" 20619 2217.34 14.23 15.29 0.103652745 Up 0.235191244 Snap23 synaptosomal-associated protein 23 K08508|1|4e-116|421|mmu:20619|synaptosomal-associated protein 23 GO:0030141//secretory granule;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0005766;GO:0042995//cell projection;GO:0012506//vesicle membrane;GO:0030141//secretory granule;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0005766;GO:0042995//cell projection;GO:0012506//vesicle membrane;GO:0030141//secretory granule;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0005766;GO:0042995//cell projection;GO:0012506//vesicle membrane GO:0000149//SNARE binding;GO:0000149//SNARE binding;GO:0000149//SNARE binding GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0065003;GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0065003;GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0065003 "gi|148696055|gb|EDL28002.1|/9.15931e-117/mCG11986, isoform CRA_b, partial [Mus musculus]" 216873 1158.06 82.87 87.73 0.082220346 Up 0.235191244 Spag7 sperm associated antigen 7 K14788|1|4e-27|124|ame:411240|ribosome biogenesis protein ENP2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0097159//organic cyclic compound binding;GO:0097159//organic cyclic compound binding - gi|537145394|gb|ERE69327.1|/5.84746e-102/calmodulin-binding transcription activator 2 isoform 2 [Cricetulus griseus] 21871 5357 15.61 14.54666667 -0.101781936 Down 0.235191244 Atp6v0a2 "ATPase, H+ transporting, lysosomal V0 subunit A2" K02154|1|0.0|1596|mmu:21871|V-type H+-transporting ATPase subunit a GO:0030666//endocytic vesicle membrane;GO:0030141//secretory granule;GO:0031224//intrinsic component of membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0005488//binding "GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0015031//protein transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006996//organelle organization;GO:0002376//immune system process;GO:0044403//symbiosis, encompassing mutualism through parasitism;GO:0006875//cellular metal ion homeostasis" gi|83627707|ref|NP_035726.2|/0/V-type proton ATPase 116 kDa subunit a isoform 2 [Mus musculus] 233979 2879.49 2.016666667 1.703333333 -0.243611851 Down 0.235144233 Tpcn2 two pore segment channel 2 K14077|1|0.0|1116|mmu:233979|two pore calcium channel protein 2 - - - - 19222 3334 2.053333333 1.743333333 -0.236119404 Down 0.235144233 Ptgir prostaglandin I receptor (IP) K04263|1|0.0|811|mmu:19222|prostacyclin receptor GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0004888//transmembrane signaling receptor activity GO:0009968//negative regulation of signal transduction;GO:0008285//negative regulation of cell proliferation;GO:0006171//cAMP biosynthetic process;GO:0009967//positive regulation of signal transduction;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0002237//response to molecule of bacterial origin gi|493688|dbj|BAA05144.1|/0/prostacyclin receptor [Mus musculus] 67493 2718 5.773333333 5.243333333 -0.138920259 Down 0.235040806 Mettl16 methyltransferase like 16 K11393|1|0.0|991|mmu:67493|methyltransferase [EC:2.1.1.-] - GO:0016741 GO:0008152//metabolic process "gi|148680830|gb|EDL12777.1|/0/methyltransferase 10 domain containing, isoform CRA_a, partial [Mus musculus]" 216848 7296 5.55 5.02 -0.144800407 Down 0.235040806 Chd3 chromodomain helicase DNA binding protein 3 K11642|1|0.0|3261|mmu:216848|chromodomain-helicase-DNA-binding protein 3 [EC:3.6.4.12] GO:0005815//microtubule organizing center;GO:0000118//histone deacetylase complex "GO:0032550;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042623//ATPase activity, coupled" "GO:0031023//microtubule organizing center organization;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" gi|357527416|ref|NP_666131.3|/0/chromodomain-helicase-DNA-binding protein 3 [Mus musculus] 23854 3819.19 25.14333333 26.81 0.092595294 Up 0.235012599 Def8 differentially expressed in FDCP 8 K19330|1|2e-42|177|cfo:105254380|run domain Beclin-1 interacting and cysteine-rich containing protein - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0007165//signal transduction;GO:0007165//signal transduction;GO:0007165//signal transduction;GO:0007165//signal transduction "gi|148679797|gb|EDL11744.1|/0/differentially expressed in FDCP 8, isoform CRA_b, partial [Mus musculus]" 217887 1915 1.55 1.846666667 0.25265526 Up 0.235012599 BC022687 cDNA sequence BC022687 - - - - gi|32526898|ref|NP_663425.2|/0/uncharacterized protein C14orf79 homolog [Mus musculus] 21345 1586 26.66666667 24.99333333 -0.093494174 Down 0.235012599 Tagln transgelin K20526|1|1e-112|409|mmu:21345|transgelin GO:0044424 GO:0003779//actin binding GO:0048513//animal organ development;GO:0006996//organelle organization gi|6755714|ref|NP_035656.1|/1.00395e-111/transgelin [Mus musculus] 14232 1734.38 82.21666667 86.91333333 0.080146636 Up 0.234956185 Fkbp8 FK506 binding protein 8 K09574|1|0.0|679|mmu:14232|FK506-binding protein 8 [EC:5.2.1.8] - - - gi|161484656|ref|NP_034353.2|/0/peptidyl-prolyl cis-trans isomerase FKBP8 isoform b [Mus musculus] 12812 2609 2.163333333 1.843333333 -0.230938998 Down 0.23493738 Coil coilin K13150|1|0.0|915|mmu:12812|coilin GO:0016604//nuclear body "GO:0016667//oxidoreductase activity, acting on a sulfur group of donors;GO:0005515//protein binding" GO:0044710 gi|134053929|ref|NP_057915.2|/0/coilin [Mus musculus] 321015 1392 2.213333333 1.893333333 -0.225292312 Down 0.23493738 5330439B14Rik RIKEN cDNA 5330439B14 gene K05033|1|4e-22|108|mmu:20928|ATP-binding cassette subfamily C (CFTR/MRP) member 9 - - - - 64383 1822 89.34333333 84.69333333 -0.07711167 Down 0.234871563 Sirt2 sirtuin 2 K11412|1|0.0|696|mmu:64383|NAD-dependent deacetylase sirtuin 2 [EC:3.5.1.-] GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0032182//ubiquitin-like protein binding;GO:0046914//transition metal ion binding;GO:0004407//histone deacetylase activity;GO:0000166//nucleotide binding;GO:0043168//anion binding;GO:0019899//enzyme binding;GO:0032182//ubiquitin-like protein binding;GO:0046914//transition metal ion binding;GO:0004407//histone deacetylase activity;GO:0000166//nucleotide binding;GO:0043168//anion binding;GO:0019899//enzyme binding;GO:0032182//ubiquitin-like protein binding;GO:0046914//transition metal ion binding;GO:0004407//histone deacetylase activity;GO:0000166//nucleotide binding;GO:0043168//anion binding;GO:0019899//enzyme binding "GO:0006351//transcription, DNA-templated;GO:0006476//protein deacetylation;GO:0014706//striated muscle tissue development;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0000087//mitotic M phase;GO:0006351//transcription, DNA-templated;GO:0006476//protein deacetylation;GO:0014706//striated muscle tissue development;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0000087//mitotic M phase;GO:0006351//transcription, DNA-templated;GO:0006476//protein deacetylation;GO:0014706//striated muscle tissue development;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0000087//mitotic M phase" "gi|148692167|gb|EDL24114.1|/0/sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae), isoform CRA_c, partial [Mus musculus]" 105522 5229 3.08 2.703333333 -0.188190937 Down 0.234862161 Ankrd28 ankyrin repeat domain 28 K15502|1|0.0|2039|mmu:105522|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A GO:0031981//nuclear lumen GO:0005488//binding - "gi|148692871|gb|EDL24818.1|/0/ankyrin repeat domain 28, isoform CRA_a, partial [Mus musculus]" 545085 2151 3.083333333 2.706666667 -0.187973638 Down 0.234862161 Wdr70 WD repeat domain 70 K02208|1|2e-97|359|bmy:Bm1_33825|cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23];K18643|2|3e-13|79.7|tru:101065628|katanin p80 WD40 repeat-containing subunit B1 - - - gi|124487149|ref|NP_001074871.1|/0/WD repeat-containing protein 70 [Mus musculus] 56214 1802 15.4 16.45333333 0.095449543 Up 0.234824552 Scamp4 secretory carrier membrane protein 4 K19995|1|7e-106|387|mmu:56214|secretory carrier-associated membrane protein "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031224//intrinsic component of membrane" - GO:0007610//behavior;GO:0045184//establishment of protein localization "gi|148699579|gb|EDL31526.1|/5.69654e-114/secretory carrier membrane protein 4, isoform CRA_c [Mus musculus]" 71702 2994 16.43333333 15.38 -0.095569643 Down 0.234824552 Cdc5l cell division cycle 5-like (S. pombe) K12860|1|0.0|1449|mmu:71702|pre-mRNA-splicing factor CDC5/CEF1 GO:0043234//protein complex;GO:0005681//spliceosomal complex;GO:0016604//nuclear body GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding "GO:0044763;GO:0000377;GO:0006351//transcription, DNA-templated" gi|50510485|dbj|BAD32228.1|/0/mKIAA0432 protein [Mus musculus] 15242 1771 4.24 3.793333333 -0.160598113 Down 0.234805747 Hhex hematopoietically expressed homeobox K08024|1|3e-110|401|mmu:15242|homeobox protein HEX GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0031369//translation initiation factor binding;GO:0008134//transcription factor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0019904//protein domain specific binding;GO:0000975//regulatory region DNA binding "GO:0045892//negative regulation of transcription, DNA-templated;GO:0006406//mRNA export from nucleus;GO:0030098//lymphocyte differentiation;GO:0016055//Wnt signaling pathway;GO:0043009//chordate embryonic development;GO:0033365//protein localization to organelle;GO:0001889//liver development;GO:0006259//DNA metabolic process;GO:0040007//growth;GO:0035270//endocrine system development;GO:0009968//negative regulation of signal transduction;GO:0006366//transcription from RNA polymerase II promoter;GO:0016331//morphogenesis of embryonic epithelium;GO:0001525//angiogenesis;GO:0003002//regionalization;GO:0021846//cell proliferation in forebrain;GO:0006950//response to stress;GO:0009725//response to hormone" gi|6680219|ref|NP_032271.1|/2.41644e-109/hematopoietically-expressed homeobox protein Hhex [Mus musculus] 380969 4871 3.746666667 4.193333333 0.162489887 Up 0.234805747 Nckap5l NCK-associated protein 5-like K18401|1|3e-157|559|acs:100558460|KAT8 regulatory NSL complex subunit 2;K09187|2|2e-07|61.6|hgl:101718411|histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43];K03006|3|1e-06|58.9|fab:101818944|DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] - - - gi|568992761|ref|XP_006521185.1|/0/PREDICTED: nck-associated protein 5-like isoform X2 [Mus musculus] 100088 2293 3.1 3.5 0.175086707 Up 0.234796344 Rcc1 regulator of chromosome condensation 1 K11493|1|0.0|733|mmu:100088|regulator of chromosome condensation GO:0000228//nuclear chromosome;GO:0000785//chromatin;GO:0005635//nuclear envelope;GO:0000228//nuclear chromosome;GO:0000785//chromatin GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031490//chromatin DNA binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0031490//chromatin DNA binding GO:0000084//mitotic S phase;GO:0019222//regulation of metabolic process;GO:0006461//protein complex assembly;GO:0007067//mitotic nuclear division;GO:0000084//mitotic S phase;GO:0019222//regulation of metabolic process;GO:0006461//protein complex assembly;GO:0007067//mitotic nuclear division "gi|148698161|gb|EDL30108.1|/0/regulator of chromosome condensation 1, isoform CRA_c [Mus musculus]" 229898 3021 4.283333333 4.763333333 0.153237557 Up 0.234702321 Gbp5 guanylate binding protein 5 K17339|1|2e-14|84.0|loa:LOAG_04490|atlastin [EC:3.6.5.-] GO:0031982//vesicle;GO:0044424 GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0034341//response to interferon-gamma "gi|148680114|gb|EDL12061.1|/0/mCG145180, isoform CRA_b, partial [Mus musculus]" 217331 3750.53 4.963333333 4.483333333 -0.146737581 Down 0.234702321 Unk unkempt family zinc finger - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - "gi|148702600|gb|EDL34547.1|/0/zinc finger CCCH type containing 5, isoform CRA_b, partial [Mus musculus]" 93834 5849 4.713333333 4.236666667 -0.15381809 Down 0.234702321 Peli2 pellino 2 K11964|1|0.0|880|mmu:93834|pellino [EC:2.3.2.27] GO:0044444//cytoplasmic part GO:0005488//binding;GO:0003824//catalytic activity GO:0001932//regulation of protein phosphorylation;GO:0002224//toll-like receptor signaling pathway;GO:0032446//protein modification by small protein conjugation;GO:0007166//cell surface receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0000165//MAPK cascade gi|118130805|ref|NP_291080.2|/0/E3 ubiquitin-protein ligase pellino homolog 2 [Mus musculus] 234839 8216 8.53 7.85 -0.119853088 Down 0.234683516 Piezo1 piezo-type mechanosensitive ion channel component 1 - - - - - 14569 2681 86.5 81.96 -0.077780148 Down 0.234683516 Gdi2 guanosine diphosphate (GDP) dissociation inhibitor 2 K17255|1|0.0|849|rno:29662|Rab GDP dissociation inhibitor GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005092//GDP-dissociation inhibitor activity;GO:0051020//GTPase binding GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization;GO:0006810//transport gi|74151913|dbj|BAE29742.1|/0/unnamed protein product [Mus musculus] 217708 2144 7.576666667 8.256666667 0.123996184 Up 0.234683516 Lin52 lin-52 homolog (C. elegans) K00710|1|2e-11|73.9|tsp:Tsp_02203|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0031981//nuclear lumen - GO:0007049//cell cycle gi|817333376|ref|XP_012293661.1|/1.30942e-59/PREDICTED: protein lin-52 homolog isoform X1 [Aotus nancymaae] 13631 6366 11.58666667 10.76666667 -0.105893917 Down 0.234655309 Eef2k eukaryotic elongation factor-2 kinase K08292|1|0.0|1437|mmu:13631|elongation factor 2 kinase [EC:2.7.11.20] - GO:0032550;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0032550;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0032550;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004683//calmodulin-dependent protein kinase activity GO:0006412//translation;GO:0001932//regulation of protein phosphorylation;GO:0006412//translation;GO:0001932//regulation of protein phosphorylation;GO:0006412//translation;GO:0001932//regulation of protein phosphorylation "gi|148685284|gb|EDL17231.1|/0/eukaryotic elongation factor-2 kinase, isoform CRA_d, partial [Mus musculus]" 319625 2245 10.75666667 9.936666667 -0.114397202 Down 0.234655309 Galm galactose mutarotase K01785|1|0.0|711|mmu:319625|aldose 1-epimerase [EC:5.1.3.3] - - - - 18584 2683 11.04333333 10.22 -0.111780506 Down 0.234655309 Pde8a phosphodiesterase 8A "K18437|1|0.0|1596|mmu:18584|high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]" - "GO:0043169//cation binding;GO:0060089;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity" "GO:0007165//signal transduction;GO:0006351//transcription, DNA-templated" "gi|6679249|ref|NP_032829.1|/0/high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A [Mus musculus]" 17184 4472 10.81666667 9.993333333 -0.114218095 Down 0.234655309 Matr3 matrin 3 K13213|1|0.0|1466|mmu:17184|matrin 3 - - - - 56322 2824.71 6.443333333 7.036666667 0.127084941 Up 0.234627101 Timm22 translocase of inner mitochondrial membrane 22 K17790|1|3e-46|189|cge:100762051|mitochondrial import inner membrane translocase subunit TIM22 GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0045184//establishment of protein localization;GO:0045184//establishment of protein localization;GO:0045184//establishment of protein localization;GO:0045184//establishment of protein localization gi|955523524|ref|XP_004433391.2|/1.25922e-84/PREDICTED: mitochondrial import inner membrane translocase subunit Tim22 [Ceratotherium simum simum] 20220 3472 6.243333333 6.83 0.129569085 Up 0.234627101 Sap18 Sin3-associated polypeptide 18 K14324|1|1e-86|324|rno:290284|histone deacetylase complex subunit SAP18 GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane - "GO:0006351//transcription, DNA-templated" gi|215490074|ref|NP_033145.2|/1.09689e-85/histone deacetylase complex subunit SAP18 [Mus musculus] 75608 1607 76.02666667 80.50666667 0.082602718 Up 0.234617699 Chmp4b charged multivesicular body protein 4B K12194|1|2e-73|279|mmu:75608|charged multivesicular body protein 4 GO:0005768//endosome GO:0005488//binding GO:0044765//single-organism transport;GO:0044763 gi|28077049|ref|NP_083638.1|/1.59573e-72/charged multivesicular body protein 4b [Mus musculus] 100504641 806 1.46 1.193333333 -0.290971282 Down 0.23458009 1700101I11Rik RIKEN cDNA 1700101I11 gene - - - - - 228775 2051 2.01 2.343333333 0.221366687 Up 0.234561285 Trib3 tribbles pseudokinase 3 K19518|1|0.0|659|mmu:228775|tribbles homolog 3 GO:0031981//nuclear lumen GO:0055103//ligase regulator activity;GO:0003712//transcription cofactor activity;GO:0019900//kinase binding;GO:0032550;GO:0019887//protein kinase regulator activity;GO:0016301//kinase activity;GO:0044389//ubiquitin-like protein ligase binding "GO:0006633//fatty acid biosynthetic process;GO:0032868//response to insulin;GO:0034976//response to endoplasmic reticulum stress;GO:0043408//regulation of MAPK cascade;GO:0015758//glucose transport;GO:0006351//transcription, DNA-templated;GO:0031398//positive regulation of protein ubiquitination;GO:0001933//negative regulation of protein phosphorylation;GO:0045444//fat cell differentiation;GO:0043393//regulation of protein binding;GO:0031331;GO:0012501//programmed cell death" gi|117553621|ref|NP_780302.2|/0/tribbles homolog 3 [Mus musculus] 235636 2460 3.676666667 3.26 -0.173526421 Down 0.234551882 Rtp3 receptor transporter protein 3 K20412|1|3e-08|63.5|cjo:107324677|peptidase inhibitor 16;K03006|3|5e-08|62.8|obi:106878530|DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K10955|4|5e-08|62.8|fab:101821326|intestinal mucin-2 GO:0044424;GO:0031224//intrinsic component of membrane - GO:0006605//protein targeting gi|148677036|gb|EDL08983.1|/0/receptor transporter protein 3 [Mus musculus] 73738 1180.42 3.896666667 3.473333333 -0.165919652 Down 0.234551882 Haus7 "HAUS augmin-like complex, subunit 7" K16590|1|9e-70|266|mmu:73738|HAUS augmin-like complex subunit 7 GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0019899//enzyme binding;GO:0019899//enzyme binding GO:0031023//microtubule organizing center organization;GO:0000087//mitotic M phase;GO:0006461//protein complex assembly;GO:0031023//microtubule organizing center organization;GO:0000087//mitotic M phase;GO:0006461//protein complex assembly gi|22094997|ref|NP_082909.1|/0/HAUS augmin-like complex subunit 7 isoform 1 [Mus musculus] 77832 2886 3.79 3.37 -0.169449257 Down 0.234551882 Tchp "trichoplein, keratin filament binding" K16811|1|2e-164|582|mmu:77832|trichoplein keratin filament-binding protein - - - - 209773 4435 3.303333333 3.723333333 0.172672223 Up 0.234551882 Dennd2a DENN/MADD domain containing 2A K20161|1|0.0|1774|mmu:209773|DENN domain-containing protein 2 GO:0005856//cytoskeleton GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport "gi|148681657|gb|EDL13604.1|/0/DENN/MADD domain containing 2A, isoform CRA_c, partial [Mus musculus]" 69654 1921.6 81.34666667 85.79333333 0.076782316 Up 0.234551882 Dctn2 dynactin 2 K10424|1|0.0|675|chx:102187922|dynactin 2 "GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0043005//neuron projection;GO:0000775//chromosome, centromeric region;GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0043005//neuron projection;GO:0000775//chromosome, centromeric region;GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0043005//neuron projection;GO:0000775//chromosome, centromeric region" GO:0005488//binding;GO:0017111//nucleoside-triphosphatase activity;GO:0005488//binding;GO:0017111//nucleoside-triphosphatase activity;GO:0005488//binding;GO:0017111//nucleoside-triphosphatase activity GO:0000087//mitotic M phase;GO:0000087//mitotic M phase;GO:0000087//mitotic M phase gi|926691871|ref|XP_005680476.2|/0/PREDICTED: dynactin subunit 2 [Capra hircus] 606735 949 1.09 1.353333333 0.312189092 Up 0.234551882 A330069E16Rik RIKEN cDNA A330069E16 gene - - - - - 223722 1893 14.17 15.20666667 0.101864188 Up 0.23450487 Mcat malonyl CoA:ACP acyltransferase (mitochondrial) K00645|1|0.0|725|mmu:223722|[acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] GO:0043231//intracellular membrane-bounded organelle GO:0004312//fatty acid synthase activity GO:0006631//fatty acid metabolic process "gi|71725343|ref|NP_001025185.1|/0/malonyl-CoA-acyl carrier protein transacylase, mitochondrial [Mus musculus]" 668173 1647 14.85333333 15.89666667 0.09793755 Up 0.23450487 Pex10 peroxisomal biogenesis factor 10 K13346|1|3e-135|484|mmu:668173|peroxin-10 GO:0031231//intrinsic component of peroxisomal membrane GO:0046872//metal ion binding;GO:0005515//protein binding GO:0006625//protein targeting to peroxisome gi|109150414|ref|NP_001035866.1|/2.59102e-134/peroxisome biogenesis factor 10 [Mus musculus] 214917 918 14.95666667 15.99333333 0.096681974 Up 0.23450487 Fam173a "family with sequence similarity 173, member A" - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|66955879|ref|NP_663385.2|/8.86216e-129/protein FAM173A isoform 1 [Mus musculus] 13356 4093.1 16.23333333 15.19333333 -0.095520848 Down 0.23450487 Dgcr2 DiGeorge syndrome critical region gene 2 K03068|1|6e-09|66.6|ocu:100009566|low density lipoprotein receptor-related protein 5/6 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding GO:0022610;GO:0042221//response to chemical;GO:0009653//anatomical structure morphogenesis;GO:0042221//response to chemical gi|157909810|ref|NP_001103220.1|/0/integral membrane protein DGCR2/IDD isoform 2 precursor [Mus musculus] 212569 2321 0.19 0.353333333 0.89503044 Up 0.234439054 Zfp273 zinc finger protein 273 K09228|1|0.0|1101|mmu:212569|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|672012642|ref|XP_006222950.2|/0/PREDICTED: zinc finger protein 345-like isoform X1 [Rattus norvegicus] 329650 10275 0.316666667 0.5 0.658963082 Up 0.234420249 Med12l mediator complex subunit 12-like K15162|1|0.0|3795|mmu:329650|mediator of RNA polymerase II transcription subunit 12 - - - gi|242397421|ref|NP_808523.2|/0/mediator of RNA polymerase II transcription subunit 12-like protein [Mus musculus] 56221 1289 0.666666667 0.466666667 -0.514573173 Down 0.234335628 Ccl24 chemokine (C-C motif) ligand 24 "K05514|1|6e-53|210|mmu:56221|C-C motif chemokine, other" GO:0044421 GO:0005125//cytokine activity GO:0001525//angiogenesis;GO:0022604//regulation of cell morphogenesis;GO:0030041//actin filament polymerization;GO:0006954//inflammatory response;GO:0030595//leukocyte chemotaxis "gi|148687414|gb|EDL19361.1|/3.43273e-56/chemokine (C-C motif) ligand 24, isoform CRA_a, partial [Mus musculus]" 100043911 4466 0.476666667 0.68 0.512554005 Up 0.234335628 Ppp4r1l-ps "protein phosphatase 4, regulatory subunit 1-like, pseudogene" K15424|1|7e-22|73.9|myb:102249786|serine/threonine-protein phosphatase 4 regulatory subunit 1 - - - "gi|148674700|gb|EDL06647.1|/7.22283e-69/mCG145743, isoform CRA_c, partial [Mus musculus]" 13106 1759 0.67 0.47 -0.511500339 Down 0.234335628 Cyp2e1 "cytochrome P450, family 2, subfamily e, polypeptide 1" "K07415|1|0.0|969|mmu:13106|cytochrome P450, family 2, subfamily E, polypeptide 1 [EC:1.14.13.-]" - - - - 327957 1055 0.24 0.41 0.772589504 Up 0.234316823 Scimp SLP adaptor and CSK interacting membrane protein - GO:0044459;GO:0001931//uropod;GO:0031252//cell leading edge;GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0043410//positive regulation of MAPK cascade gi|113865879|ref|NP_001038991.1|/1.2862e-84/SLP adapter and CSK-interacting membrane protein [Mus musculus] 20878 1897 0.776666667 1.01 0.378987839 Up 0.234288616 Aurka aurora kinase A K11481|1|0.0|800|mmu:20878|aurora kinase A [EC:2.7.11.1] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0000922//spindle pole;GO:0044444//cytoplasmic part;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0000922//spindle pole;GO:0044444//cytoplasmic part GO:0032550;GO:0004672//protein kinase activity;GO:0019900//kinase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0032550;GO:0004672//protein kinase activity;GO:0019900//kinase binding;GO:0044389//ubiquitin-like protein ligase binding GO:0010608//posttranscriptional regulation of gene expression;GO:0043627//response to estrogen;GO:0000087//mitotic M phase;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0016043//cellular component organization;GO:0010608//posttranscriptional regulation of gene expression;GO:0043627//response to estrogen;GO:0000087//mitotic M phase;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0016043//cellular component organization gi|46358064|ref|NP_035627.1|/0/aurora kinase A isoform a [Mus musculus] 26411 2699 0.78 1.013333333 0.377562794 Up 0.234288616 Map4k1 mitogen-activated protein kinase kinase kinase kinase 1 K04408|1|0.0|1442|mmu:26411|mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1] - GO:0032550;GO:0030695//GTPase regulator activity;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction gi|101944153|ref|NP_032305.2|/0/mitogen-activated protein kinase kinase kinase kinase 1 [Mus musculus] 75747 2158 0.75 0.976666667 0.380975663 Up 0.234288616 Sesn3 sestrin 3 K10141|1|0.0|889|mmu:75747|sestrin 1/3 - - - - 67811 1951 83.31333333 79.04666667 -0.075842774 Down 0.234251006 Poldip2 "polymerase (DNA-directed), delta interacting protein 2" K17809|1|0.0|698|mmu:67811|polymerase delta-interacting protein 2 GO:0005759//mitochondrial matrix GO:0003676//nucleic acid binding GO:0007005//mitochondrion organization gi|14780884|ref|NP_080665.1|/0/polymerase delta-interacting protein 2 [Mus musculus] 14055 4224 15.14333333 14.11333333 -0.101624036 Down 0.234241604 Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit K17451|1|0.0|1530|mmu:14055|histone-lysine N-methyltransferase EZH1 [EC:2.1.1.43] - - - - 19411 2777.69 14.76333333 15.79666667 0.097601664 Up 0.234241604 Rarg "retinoic acid receptor, gamma" K08529|1|0.0|816|pon:100444155|retinoic acid receptor gamma - - - - 654795 1243 82.05333333 77.81 -0.076606363 Down 0.234213397 Sdr39u1 "short chain dehydrogenase/reductase family 39U, member 1" K07071|1|1e-156|555|mmu:654795|uncharacterized protein - GO:0048037//cofactor binding GO:0008152//metabolic process gi|81889153|sp|Q5M8N4.1|D39U1_MOUSE/1.05699e-155/RecName: Full=Epimerase family protein SDR39U1; AltName: Full=Short-chain dehydrogenase/reductase family 39U member 1 381549 2381 0.573333333 0.786666667 0.456378295 Up 0.234185189 Zfp69 zinc finger protein 69 K09228|1|0.0|1240|mmu:381549|KRAB domain-containing zinc finger protein - - - gi|238859629|ref|NP_001005788.2|/0/zinc finger protein 69 [Mus musculus] 75475 3970 25.53 23.92 -0.093976148 Down 0.234175787 Oplah 5-oxoprolinase (ATP-hydrolysing) K01469|1|0.0|2347|mmu:75475|5-oxoprolinase (ATP-hydrolysing) [EC:3.5.2.9] - "GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0032550" GO:0006790//sulfur compound metabolic process gi|568993566|ref|XP_006521571.1|/0/PREDICTED: 5-oxoprolinase isoform X3 [Mus musculus] 67956 2682.54 76.25666667 80.44333333 0.077109395 Up 0.23414758 Setd8 lysine methyltransferase 5A K11428|1|0.0|644|pon:100451760|histone-lysine N-methyltransferase SETD8 [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0016279//protein-lysine N-methyltransferase activity;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0016279//protein-lysine N-methyltransferase activity "GO:0006351//transcription, DNA-templated;GO:0016571//histone methylation;GO:0018022//peptidyl-lysine methylation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0000087//mitotic M phase;GO:0006366//transcription from RNA polymerase II promoter;GO:0016571//histone methylation;GO:0018022//peptidyl-lysine methylation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0000087//mitotic M phase;GO:0006351//transcription, DNA-templated;GO:0016571//histone methylation;GO:0018022//peptidyl-lysine methylation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0000087//mitotic M phase;GO:0006351//transcription, DNA-templated;GO:0016571//histone methylation;GO:0018022//peptidyl-lysine methylation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0000087//mitotic M phase" gi|894216270|ref|NP_001297652.1|/1.55306e-180/N-lysine methyltransferase SETD8 isoform 2 [Mus musculus] 54722 2133 0.113333333 0.256666667 1.179323699 Up 0.23414758 Dfna5 "deafness, autosomal dominant 5 (human)" - - - GO:0008283//cell proliferation;GO:0012502//induction of programmed cell death;GO:0042490//mechanoreceptor differentiation gi|9055204|ref|NP_061239.1|/0/non-syndromic hearing impairment protein 5 homolog [Mus musculus] 24013 7462 0.503333333 0.32 -0.653442239 Down 0.23410997 Grk1 G protein-coupled receptor kinase 1 K00909|1|0.0|1116|mmu:24013|rhodopsin kinase [EC:2.7.11.14] - GO:0032550;GO:0004674//protein serine/threonine kinase activity GO:0042461//photoreceptor cell development;GO:0042221//response to chemical;GO:0012501//programmed cell death;GO:0050953//sensory perception of light stimulus;GO:0009886//post-embryonic morphogenesis;GO:0006468//protein phosphorylation;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0009314//response to radiation gi|13633680|sp|Q9WVL4.1|RK_MOUSE/0/RecName: Full=Rhodopsin kinase; Short=RK; AltName: Full=G protein-coupled receptor kinase 1; Flags: Precursor 11534 1805.99 73.53 77.69333333 0.079457825 Up 0.234091166 Adk adenosine kinase K00856|1|0.0|724|mmu:11534|adenosine kinase [EC:2.7.1.20] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0032550;GO:0043169//cation binding;GO:0019206//nucleoside kinase activity GO:0009153;GO:0003300//cardiac muscle hypertrophy;GO:0006167//AMP biosynthetic process;GO:0009112;GO:0043101//purine-containing compound salvage;GO:0007623//circadian rhythm;GO:0042098//T cell proliferation gi|19527306|ref|NP_598840.1|/0/adenosine kinase isoform 1 [Mus musculus] 105180375 1251 2.783333333 2.423333333 -0.199820833 Down 0.234053556 Tmem265 transmembrane protein 265 - - - - gi|655886329|ref|XP_008246955.1|/6.8459e-46/PREDICTED: uncharacterized protein LOC100343761 isoform X1 [Oryctolagus cuniculus] 319513 3405.13 2.393333333 2.756666667 0.203903485 Up 0.234053556 Pced1a PC-esterase domain containing 1A - - - - "gi|148696319|gb|EDL28266.1|/0/RIKEN cDNA A930025D01, isoform CRA_b, partial [Mus musculus]" 52700 1446 26.34666667 27.94666667 0.08505577 Up 0.234025349 Txndc17 thioredoxin domain containing 17 K00685|1|1e-21|107|tsp:Tsp_00010|arginine-tRNA-protein transferase [EC:2.3.2.8];K00771|2|2e-19|99.4|smm:Smp_128310.1|protein xylosyltransferase [EC:2.4.2.26] GO:0044444//cytoplasmic part "GO:0016209//antioxidant activity;GO:0016668//oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor" GO:0019221//cytokine-mediated signaling pathway;GO:0044710 gi|13386060|ref|NP_080835.1|/3.89324e-67/thioredoxin domain-containing protein 17 [Mus musculus] 106633 5814 1.256666667 1.01 -0.31524673 Down 0.233903118 Ift140 intraflagellar transport 140 K19672|1|0.0|2949|mmu:106633|intraflagellar transport protein 140 - - - gi|184186088|ref|NP_598887.3|/0/intraflagellar transport protein 140 homolog [Mus musculus] 319480 4937 1.246666667 1 -0.318075769 Down 0.233903118 Itga11 integrin alpha 11 K06587|1|0.0|2383|mmu:319480|integrin alpha 11 GO:0005887//integral component of plasma membrane GO:0043169//cation binding GO:0007166//cell surface receptor signaling pathway;GO:0022610 gi|225703035|ref|NP_795896.4|/0/integrin alpha-11 precursor [Mus musculus] 19091 6992 1.013333333 1.266666667 0.321928095 Up 0.233903118 Prkg1 "protein kinase, cGMP-dependent, type I" K07376|1|0.0|1168|cge:100768615|cGMP-dependent protein kinase 1 [EC:2.7.11.12] GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0032550;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0030551//cyclic nucleotide binding;GO:0016247//channel regulator activity;GO:0032550;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0030551//cyclic nucleotide binding;GO:0016247//channel regulator activity GO:0007010//cytoskeleton organization;GO:0007599//hemostasis;GO:0031175//neuron projection development;GO:0007154//cell communication;GO:0007420//brain development;GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0006464//cellular protein modification process;GO:0016477//cell migration;GO:0007010//cytoskeleton organization;GO:0007599//hemostasis;GO:0031175//neuron projection development;GO:0007154//cell communication;GO:0007420//brain development;GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0006464//cellular protein modification process;GO:0016477//cell migration gi|6755156|ref|NP_035290.1|/0/cGMP-dependent protein kinase 1 beta isoform [Mus musculus] 229488 4392 25.01333333 23.42666667 -0.094545637 Down 0.233893715 Fam160a1 "family with sequence similarity 160, member A1" "K11972|1|5e-08|63.5|bfo:BRAFLDRAFT_87257|E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.27];K16913|3|5e-06|57.0|tup:102495998|proline-, glutamic acid- and leucine-rich protein 1;K14835|4|6e-06|56.6|aec:105152036|ribosomal RNA methyltransferase Nop2 [EC:2.1.1.-];K19538|5|8e-06|56.2|ptr:750377|retinitis pigmentosa 1" - - - gi|158341634|ref|NP_766270.2|/0/protein FAM160A1 [Mus musculus] 11992 1345 72.70333333 68.66666667 -0.082411579 Down 0.233856106 Auh AU RNA binding protein/enoyl-coenzyme A hydratase K05607|1|1e-153|545|mmu:11992|methylglutaconyl-CoA hydratase [EC:4.2.1.18] GO:0044429 GO:0003729//mRNA binding;GO:0016836//hydro-lyase activity GO:0006551//leucine metabolic process;GO:0006401//RNA catabolic process;GO:0009063//cellular amino acid catabolic process "gi|116268115|ref|NP_057918.2|/1.22419e-152/methylglutaconyl-CoA hydratase, mitochondrial precursor [Mus musculus]" 211253 1862 5.606666667 5.083333333 -0.141368463 Down 0.233809094 Mtrf1 mitochondrial translational release factor 1 K02835|1|0.0|814|mmu:211253|peptide chain release factor 1 GO:0043231//intracellular membrane-bounded organelle GO:0003747//translation release factor activity GO:0006412//translation "gi|568987171|ref|XP_006518835.1|/0/PREDICTED: peptide chain release factor 1, mitochondrial isoform X1 [Mus musculus]" 56716 3361 5.603333333 5.086666667 -0.139564762 Down 0.233809094 Mlst8 "MTOR associated protein, LST8 homolog (S. cerevisiae)" K08266|1|1e-158|563|mmu:56716|target of rapamycin complex subunit LST8 GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part - GO:0001934//positive regulation of protein phosphorylation;GO:0030041//actin filament polymerization;GO:0009967//positive regulation of signal transduction;GO:0001934//positive regulation of protein phosphorylation;GO:0030041//actin filament polymerization;GO:0009967//positive regulation of signal transduction;GO:0001934//positive regulation of protein phosphorylation;GO:0030041//actin filament polymerization;GO:0009967//positive regulation of signal transduction;GO:0001934//positive regulation of protein phosphorylation;GO:0030041//actin filament polymerization;GO:0009967//positive regulation of signal transduction gi|569001123|ref|XP_006524742.1|/1.25819e-157/PREDICTED: target of rapamycin complex subunit LST8 isoform X2 [Mus musculus] 212123 2312 5.043333333 5.566666667 0.142436115 Up 0.233809094 Dcaf15 DDB1 and CUL4 associated factor 15 K11791|1|0.0|1122|mmu:212123|DDB1- and CUL4-associated factor 15 - - GO:0032446//protein modification by small protein conjugation gi|124249333|ref|NP_766090.2|/0/DDB1- and CUL4-associated factor 15 [Mus musculus] 30059 682 75.71666667 71.73666667 -0.077900189 Down 0.233724473 Timm10 translocase of inner mitochondrial membrane 10 K17778|1|1e-45|185|ecb:100066829|mitochondrial import inner membrane translocase subunit TIM10 GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space GO:0046914//transition metal ion binding;GO:0042802//identical protein binding GO:0050954//sensory perception of mechanical stimulus;GO:0006626//protein targeting to mitochondrion;GO:0019538//protein metabolic process gi|6912708|ref|NP_036588.1|/7.47186e-45/mitochondrial import inner membrane translocase subunit Tim10 [Homo sapiens] 70312 2724 10.58 11.38 0.10516093 Up 0.233611644 Cactin "cactin, spliceosome C complex subunit" K15631|1|5e-19|99.4|dvi:Dvir_GJ19188|molybdenum cofactor sulfurtransferase [EC:2.8.1.9] GO:0005681//spliceosomal complex GO:0005488//binding GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0002832;GO:0002224//toll-like receptor signaling pathway;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0001932//regulation of protein phosphorylation;GO:0034612//response to tumor necrosis factor;GO:0032480//negative regulation of type I interferon production;GO:0000377;GO:0070555//response to interleukin-1 gi|148699481|gb|EDL31428.1|/0/mCG12128 [Mus musculus] 53609 2316.08 9.753333333 10.55 0.11327573 Up 0.233611644 Clasrp CLK4-associating serine/arginine rich protein "K13168|1|8e-48|157|chx:102170870|splicing factor, arginine/serine-rich 16" - - - gi|568946205|ref|XP_006540256.1|/2.52886e-49/PREDICTED: CLK4-associating serine/arginine rich protein isoform X4 [Mus musculus] 50759 1256 0.393333333 0.583333333 0.568568062 Up 0.233611644 Fbxo16 F-box protein 16 K10299|1|0.0|639|mmu:50759|F-box protein 16 - - - gi|7657079|ref|NP_056610.1|/0/F-box only protein 16 [Mus musculus] 14062 3296 10.30333333 11.10666667 0.108314747 Up 0.233611644 F2r coagulation factor II (thrombin) receptor K03914|1|0.0|763|mmu:14062|coagulation factor II (thrombin) receptor GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0016021//integral component of membrane;GO:0097060//synaptic membrane GO:0008528//G-protein coupled peptide receptor activity;GO:0032403//protein complex binding "GO:0002246//wound healing involved in inflammatory response;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0001775//cell activation;GO:0001894//tissue homeostasis;GO:0019229//regulation of vasoconstriction;GO:0033363//secretory granule organization;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032611//interleukin-1 beta production;GO:0007596//blood coagulation;GO:0019233//sensory perception of pain;GO:0006351//transcription, DNA-templated;GO:0007259//JAK-STAT cascade;GO:0003093//regulation of glomerular filtration;GO:0043410//positive regulation of MAPK cascade;GO:0016477//cell migration;GO:0032675//regulation of interleukin-6 production;GO:0006606//protein import into nucleus;GO:0002237//response to molecule of bacterial origin;GO:0050715//positive regulation of cytokine secretion;GO:0050709//negative regulation of protein secretion;GO:0051283//negative regulation of sequestering of calcium ion;GO:0006939//smooth muscle contraction;GO:0007528//neuromuscular junction development;GO:0008283//cell proliferation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0006468//protein phosphorylation" gi|22165402|ref|NP_034299.2|/0/proteinase-activated receptor 1 precursor [Mus musculus] 67705 1073.76 74.01333333 70.09666667 -0.078439352 Down 0.233583437 1810058I24Rik RIKEN cDNA 1810058I24 gene "K19479|1|6e-10|67.8|cjc:100391215|collagen, type X, alpha" - - - - 81489 3003.89 6.076666667 6.653333333 0.130797159 Up 0.233564632 Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 K09507|1|1e-173|595|tup:102499411|DnaJ homolog subfamily B member 1 - - - - 241308 6154.44 1.343333333 1.62 0.270176475 Up 0.233545827 Ralgps1 Ral GEF with PH domain and SH3 binding motif 1 K03099|1|8e-21|106|sko:100376216|son of sevenless;K17639|2|4e-20|104|pbi:103060131|ral guanine nucleotide dissociation stimulator-like 3;K04349|3|9e-20|103|mze:101475482|Ras-specific guanine nucleotide-releasing factor 1 - - - gi|635071097|ref|XP_008004383.1|/0/PREDICTED: ras-specific guanine nucleotide-releasing factor RalGPS1 isoform X10 [Chlorocebus sabaeus] 56327 869 66.68333333 70.56 0.081524338 Up 0.233442401 Arl2 ADP-ribosylation factor-like 2 K07943|1|4e-103|376|rro:104662836|ADP-ribosylation factor-like protein 2 GO:0005815//microtubule organizing center;GO:0005740//mitochondrial envelope;GO:0044459 GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0004857//enzyme inhibitor activity GO:0043087//regulation of GTPase activity;GO:0007043//cell-cell junction assembly;GO:0034504//protein localization to nucleus;GO:0010810//regulation of cell-substrate adhesion;GO:0006812//cation transport;GO:0031023//microtubule organizing center organization;GO:0031112;GO:0043623//cellular protein complex assembly;GO:0035556//intracellular signal transduction gi|724827248|ref|XP_010362261.1|/2.87388e-102/PREDICTED: ADP-ribosylation factor-like protein 2 [Rhinopithecus roxellana] 104394 2024 23.17 24.72666667 0.093809723 Up 0.233414194 E2f4 E2F transcription factor 4 K04682|1|2e-153|545|mmu:104394|transcription factor E2F4/5 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding "GO:0010927;GO:0032535//regulation of cellular component size;GO:0019725//cellular homeostasis;GO:0030855//epithelial cell differentiation;GO:0003013//circulatory system process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation" gi|22507329|ref|NP_683754.1|/1.60654e-152/transcription factor E2F4 [Mus musculus] 70885 4251.24 4.396666667 4.863333333 0.145535319 Up 0.233301365 Ints10 integrator complex subunit 10 K13147|1|0.0|1391|mmu:70885|integrator complex subunit 10 - - - gi|658132449|ref|NP_001280721.1|/0/integrator complex subunit 10 isoform 2 [Mus musculus] 66411 1173 23.08666667 24.63333333 0.093551977 Up 0.23328256 Tbcb tubulin folding cofactor B K17262|1|6e-126|452|mmu:66411|tubulin-folding cofactor B GO:0015630//microtubule cytoskeleton - GO:0048731//system development;GO:0048869//cellular developmental process gi|170650659|ref|NP_079824.2|/5.175e-125/tubulin-folding cofactor B [Mus musculus] 29871 3233.08 22.93333333 24.48 0.094157494 Up 0.23328256 Scmh1 sex comb on midleg homolog 1 K11461|1|0.0|1224|mmu:29871|polycomb protein SCMH1 GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0043231//intracellular membrane-bounded organelle;GO:0044427 - "GO:0016568//chromatin modification;GO:0003002//regionalization;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0016568//chromatin modification;GO:0003002//regionalization;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated" gi|227499783|ref|NP_001153102.1|/0/polycomb protein SCMH1 isoform 2 [Mus musculus] 381812 1094 0.413333333 0.246666667 -0.744742945 Down 0.233244951 Cracr2a calcium release activated channel regulator 2A K17199|1|3e-168|593|mmu:381812|Ras and EF-hand domain-containing protein - - - - 18725 3464 0.256666667 0.43 0.744440715 Up 0.233244951 Pira2 paired-Ig-like receptor A2 K06512|1|0.0|1288|mmu:18725|leukocyte immunoglobulin-like receptor - - - gi|133892525|ref|NP_035219.2|/0/paired-Ig-like receptor A2 precursor [Mus musculus] 17898 599 0.603333333 0.41 -0.557331382 Down 0.233226146 Myl7 "myosin, light polypeptide 7, regulatory" K12754|1|3e-83|309|mmu:17898|myosin regulatory light chain 7 GO:0030425//dendrite;GO:0030017//sarcomere;GO:0015629//actin cytoskeleton GO:0043169//cation binding - "gi|114326499|ref|NP_075017.2|/2.49746e-82/myosin regulatory light chain 2, atrial isoform [Mus musculus]" 100502933 3112 3.676666667 4.113333333 0.161909604 Up 0.233207341 Gm19461 "predicted gene, 19461" - - - - - 67226 3010 3.82 4.256666667 0.156151481 Up 0.233207341 Tmem19 transmembrane protein 19 - GO:0031224//intrinsic component of membrane - - "gi|148689821|gb|EDL21768.1|/2.40622e-166/transmembrane protein 19, isoform CRA_c [Mus musculus]" 624784 2896 0.01 0.096666667 3.273018494 Up 0.233188537 Gm9855 thymine DNA glycosylase pseudogene K03649|1|0.0|711|mmu:21665|TDG/mug DNA glycosylase family protein [EC:3.2.2.-] GO:0016604//nuclear body "GO:0000700;GO:0003690//double-stranded DNA binding;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0032182//ubiquitin-like protein binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" GO:0006281//DNA repair;GO:0043393//regulation of protein binding;GO:0035561//regulation of chromatin binding;GO:0006366//transcription from RNA polymerase II promoter gi|37589917|gb|AAH10315.2|/0/Thymine DNA glycosylase [Mus musculus] 22364 602 0.096666667 0.01 -3.273018494 Down 0.233188537 Vpreb3 pre-B lymphocyte gene 3 K06553|1|7e-60|231|mmu:22364|pre-B lymphocyte gene - - - gi|6678579|ref|NP_033540.1|/5.05405e-59/pre-B lymphocyte protein 3 precursor [Mus musculus] 105663 2839 7.493333333 8.156666667 0.122372066 Up 0.233188537 Thtpa thiamine triphosphatase K05307|1|1e-121|440|mmu:105663|thiamine-triphosphatase [EC:3.6.1.28] GO:0031981//nuclear lumen GO:0043169//cation binding;GO:0017111//nucleoside-triphosphatase activity GO:0042723//thiamine-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process "gi|910751148|pdb|5A64|A/1.09178e-120/Chain A, Crystal Structure Of Mouse Thiamine Triphosphatase In Complex With Thiamine Triphosphate." 74872 604 0.096666667 0.01 -3.273018494 Down 0.233188537 4930448H16Rik RIKEN cDNA 4930448H16 gene - - - - "gi|148687117|gb|EDL19064.1|/1.16622e-42/mCG23563, partial [Mus musculus]" 76803 1491 0.096666667 0.01 -3.273018494 Down 0.233188537 2410141K09Rik RIKEN cDNA 2410141K09 gene K09228|1|4e-32|139|mmu:105245545|KRAB domain-containing zinc finger protein - - - gi|46810309|ref|NP_898942.1|/2.84925e-52/zinc finger protein-like isoform b [Mus musculus] 330962 488 0.01 0.096666667 3.273018494 Up 0.233188537 Slc51b "solute carrier family 51, beta subunit" K14361|1|3e-67|255|mmu:330962|organic solute transporter subunit beta GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex GO:0046983//protein dimerization activity GO:0010608//posttranscriptional regulation of gene expression;GO:0090313;GO:0006486//protein glycosylation;GO:0032527//protein exit from endoplasmic reticulum;GO:0015718//monocarboxylic acid transport gi|30725804|ref|NP_849264.1|/2.20135e-66/organic solute transporter subunit beta [Mus musculus] 382523 563 0.01 0.096666667 3.273018494 Up 0.233188537 Gm12260 predicted gene 12260 K11253|1|2e-72|273|pon:100440619|histone H3 - - - - 381409 2965 0.096666667 0.01 -3.273018494 Down 0.233188537 Cdh26 cadherin-like 26 "K06736|1|1e-83|313|ola:101162000|cadherin 2, type 1, N-cadherin" - - - - 100042314 874 0.01 0.096666667 3.273018494 Up 0.233188537 Gm10639 predicted gene 10639 K00799|1|1e-108|395|mmu:14858|glutathione S-transferase [EC:2.5.1.18] GO:0031965//nuclear membrane;GO:0044444//cytoplasmic part "GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0072341//modified amino acid binding" GO:0006805//xenobiotic metabolic process;GO:0044767//single-organism developmental process gi|169808401|ref|NP_001116132.1|/2.62811e-111/uncharacterized protein LOC100042314 [Mus musculus] 75604 981 0.01 0.096666667 3.273018494 Up 0.233188537 Tm4sf5 transmembrane 4 superfamily member 5 - GO:0031224//intrinsic component of membrane - - gi|238550162|ref|NP_083636.2|/7.65838e-97/transmembrane 4 L6 family member 5 [Mus musculus] 670833 492 0.01 0.096666667 3.273018494 Up 0.233188537 Gm11213 predicted gene 11213 - - - - gi|149059579|gb|EDM10517.1|/2.00117e-17/rCG55276 [Rattus norvegicus] 57776 2572 0.48 0.68 0.502500341 Up 0.233103915 Ttyh1 tweety family member 1 K02923|1|9e-68|261|cmy:102946987|large subunit ribosomal protein L38e GO:0030175//filopodium;GO:0043005//neuron projection;GO:0005789//endoplasmic reticulum membrane;GO:0034702//ion channel complex;GO:0030175//filopodium;GO:0043005//neuron projection;GO:0005789//endoplasmic reticulum membrane;GO:0034702//ion channel complex;GO:0030175//filopodium;GO:0043005//neuron projection;GO:0005789//endoplasmic reticulum membrane;GO:0034702//ion channel complex;GO:0030175//filopodium;GO:0043005//neuron projection;GO:0005789//endoplasmic reticulum membrane;GO:0034702//ion channel complex GO:0005253//anion channel activity;GO:0046872//metal ion binding;GO:0005253//anion channel activity;GO:0046872//metal ion binding;GO:0005253//anion channel activity;GO:0046872//metal ion binding;GO:0005253//anion channel activity;GO:0046872//metal ion binding GO:0000087//mitotic M phase;GO:0007155//cell adhesion;GO:0015698//inorganic anion transport;GO:0030031//cell projection assembly;GO:0000087//mitotic M phase;GO:0007155//cell adhesion;GO:0015698//inorganic anion transport;GO:0030031//cell projection assembly;GO:0000087//mitotic M phase;GO:0007155//cell adhesion;GO:0015698//inorganic anion transport;GO:0030031//cell projection assembly;GO:0000087//mitotic M phase;GO:0007155//cell adhesion;GO:0015698//inorganic anion transport;GO:0030031//cell projection assembly "gi|148699270|gb|EDL31217.1|/0/tweety homolog 1 (Drosophila), isoform CRA_e, partial [Mus musculus]" 380705 1941 0.256666667 0.116666667 -1.137503524 Down 0.233075708 Tmem102 transmembrane protein 102 K04358|1|9e-129|463|cfa:607829|fibroblast growth factor;K16271|3|1e-123|446|chx:102190496|E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27] - - - gi|145966766|ref|NP_001028605.2|/0/transmembrane protein 102 [Mus musculus] 17776 5711.88 69.40666667 65.66666667 -0.07991302 Down 0.233056903 Mast2 microtubule associated serine/threonine kinase 2 K08789|1|0.0|3001|mmu:17776|microtubule-associated serine/threonine kinase [EC:2.7.11.1] GO:0005856//cytoskeleton;GO:0005856//cytoskeleton GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0019899//enzyme binding;GO:0015631//tubulin binding;GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0019899//enzyme binding;GO:0015631//tubulin binding GO:0032655;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0003006//developmental process involved in reproduction;GO:0032655;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0003006//developmental process involved in reproduction gi|112363078|ref|NP_032667.2|/0/microtubule-associated serine/threonine-protein kinase 2 isoform 2 [Mus musculus] 71978 4058 14.3 15.3 0.097516506 Up 0.233009891 Ppp2r2a "protein phosphatase 2, regulatory subunit B, alpha" K04354|1|0.0|703|tup:102488546|serine/threonine-protein phosphatase 2A regulatory subunit B GO:0008287//protein serine/threonine phosphatase complex;GO:0044444//cytoplasmic part;GO:0008287//protein serine/threonine phosphatase complex;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0019888//protein phosphatase regulator activity;GO:0004721//phosphoprotein phosphatase activity;GO:0005488//binding;GO:0019888//protein phosphatase regulator activity;GO:0004721//phosphoprotein phosphatase activity GO:0014072//response to isoquinoline alkaloid;GO:0006464//cellular protein modification process;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0007154//cell communication;GO:0014072//response to isoquinoline alkaloid;GO:0006464//cellular protein modification process;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0007154//cell communication gi|60360266|dbj|BAD90377.1|/0/mKIAA4213 protein [Mus musculus] 15936 1541 14.77333333 13.77666667 -0.100768518 Down 0.233009891 Ier2 immediate early response 2 - - - - - 56444 4022 13.67666667 14.67666667 0.10180769 Up 0.233009891 Actr10 ARP10 actin-related protein 10 K16576|1|0.0|840|mmu:56444|actin-related protein 10 GO:0005875//microtubule associated complex - GO:0006928//movement of cell or subcellular component gi|226246593|ref|NP_062759.2|/0/actin-related protein 10 [Mus musculus] 70974 8641 1.006666667 0.78 -0.36804002 Down 0.232962879 Pgm2l1 phosphoglucomutase 2-like 1 "K11809|1|0.0|1235|mmu:70974|glucose-1,6-bisphosphate synthase [EC:2.7.1.106]" - - - "gi|28076969|ref|NP_081905.1|/0/glucose 1,6-bisphosphate synthase [Mus musculus]" 93683 4626 2.526666667 2.183333333 -0.210702942 Down 0.232859453 Glce glucuronyl C5-epimerase K01793|1|0.0|1260|mmu:93683|heparosan-N-sulfate-glucuronate 5-epimerase [EC:5.1.3.17] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives" GO:0030166//proteoglycan biosynthetic process;GO:0006024//glycosaminoglycan biosynthetic process gi|65301488|ref|NP_201577.3|/0/D-glucuronyl C5-epimerase [Mus musculus] 73172 1990 0.903333333 1.14 0.335703474 Up 0.232850051 Exo5 exonuclease 5 K17815|1|0.0|721|mmu:73172|exonuclease V [EC:3.1.-.-] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0051536//iron-sulfur cluster binding;GO:0008297//single-stranded DNA exodeoxyribonuclease activity;GO:0051536//iron-sulfur cluster binding;GO:0008297//single-stranded DNA exodeoxyribonuclease activity GO:0006281//DNA repair;GO:0006281//DNA repair gi|21312139|ref|NP_082733.1|/0/exonuclease V [Mus musculus] 11843 2042 24.42 25.95 0.087671338 Up 0.232821844 Arf4 ADP-ribosylation factor 4 K07939|1|7e-98|360|cge:100769922|ADP-ribosylation factor 4 GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0032550 GO:0007417//central nervous system development;GO:0006810//transport;GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization;GO:0009611//response to wounding;GO:0038127//ERBB signaling pathway gi|431899854|gb|ELK07801.1|/1.49371e-97/ADP-ribosylation factor 4 [Pteropus alecto] 320973 528 2.67 3.036666667 0.185648811 Up 0.232765429 D330023K18Rik RIKEN cDNA D330023K18 gene - - - - gi|568913811|ref|XP_006498160.1|/5.43018e-25/PREDICTED: protein GPR107 isoform X1 [Mus musculus] 78887 4025 3.02 2.653333333 -0.18674262 Down 0.232765429 Sfi1 "Sfi1 homolog, spindle assembly associated (yeast)" K16489|1|0.0|2226|mmu:78887|protein SFI1 - - - - 268882 4110 3.3 3.71 0.168953162 Up 0.232746625 Fbxo45 F-box protein 45 K10319|1|5e-146|521|pale:102886056|F-box protein 45 GO:0044327//dendritic spine head;GO:0097060//synaptic membrane - GO:0048731//system development;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0033554//cellular response to stress;GO:0016567//protein ubiquitination gi|984102024|ref|XP_015342308.1|/4.32639e-145/PREDICTED: F-box/SPRY domain-containing protein 1 [Marmota marmota marmota] 207214 6527 3.703333333 3.293333333 -0.16927587 Down 0.232746625 Larp4 "La ribonucleoprotein domain family, member 4" K18763|1|0.0|1312|mmu:207214|la-related protein 4 - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0000902//cell morphogenesis;GO:0006996//organelle organization;GO:0000902//cell morphogenesis;GO:0006996//organelle organization;GO:0000902//cell morphogenesis;GO:0006996//organelle organization;GO:0000902//cell morphogenesis;GO:0006996//organelle organization;GO:0000902//cell morphogenesis;GO:0006996//organelle organization gi|124358932|ref|NP_001074417.1|/0/la-related protein 4 isoform 2 [Mus musculus] 215707 2256 0.673333333 0.893333333 0.407877708 Up 0.232680808 Ccdc92 coiled-coil domain containing 92 K16452|1|2e-155|552|mmu:215707|coiled-coil domain-containing protein 92 GO:0005813//centrosome GO:0005488//binding - gi|148687623|gb|EDL19570.1|/1.50037e-154/coiled-coil domain containing 92 [Mus musculus] 22717 3815 0.896666667 0.676666667 -0.406126445 Down 0.232680808 Zfp59 zinc finger protein 59 K09228|1|0.0|928|mmu:338354|KRAB domain-containing zinc finger protein - - - gi|124269715|ref|NP_035892.2|/0/zinc finger protein 59 [Mus musculus] 225929 4221 14.77 13.78 -0.100093938 Down 0.232680808 Patl1 protein associated with topoisomerase II homolog 1 (yeast) K12617|1|0.0|1158|mmu:225929|DNA topoisomerase 2-associated protein PAT1 GO:0043234//protein complex;GO:0016604//nuclear body;GO:0035770//ribonucleoprotein granule;GO:0044444//cytoplasmic part GO:0008187//poly-pyrimidine tract binding;GO:0070717//poly-purine tract binding;GO:0045182//translation regulator activity "GO:0006412//translation;GO:0022618//ribonucleoprotein complex assembly;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" gi|255522964|ref|NP_766223.2|/0/protein PAT1 homolog 1 [Mus musculus] 228866 2752 13.61333333 14.6 0.100948004 Up 0.232680808 Pcif1 PDX1 C-terminal inhibiting factor 1 K17584|1|0.0|1444|cge:100771480|phosphorylated CTD-interacting factor 1 GO:0043231//intracellular membrane-bounded organelle - GO:0010921//regulation of phosphatase activity gi|344241581|gb|EGV97684.1|/0/Phosphorylated CTD-interacting factor 1 [Cricetulus griseus] 74741 4297.95 3.306666667 2.913333333 -0.182706841 Down 0.232643198 C2cd5 C2 calcium-dependent domain containing 5 K20045|1|7e-07|59.7|nve:NEMVE_v1g202524|intersectin;K15290|2|2e-06|58.5|tsp:Tsp_06980|synaptotagmin-1;K17630|5|2e-06|58.5|mcc:719871|Ras GTPase-activating protein 4 - - - gi|50510517|dbj|BAD32244.1|/0/mKIAA0528 protein [Mus musculus] 13429 3795.31 3.223333333 2.836666667 -0.184356758 Down 0.232643198 Dnm1 dynamin 1 K01528|1|0.0|1519|rno:140694|dynamin GTPase [EC:3.6.5.5] GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008289//lipid binding;GO:0005515//protein binding GO:0006996//organelle organization;GO:0009154//purine ribonucleotide catabolic process;GO:0006898//receptor-mediated endocytosis;GO:0006996//organelle organization;GO:0006898//receptor-mediated endocytosis gi|32172431|sp|P39053.2|DYN1_MOUSE/0/RecName: Full=Dynamin-1 76974 675 0.603333333 0.413333333 -0.545649577 Down 0.232633796 Urah urate (5-hydroxyiso-) hydrolase K07127|1|2e-65|250|mmu:76974|5-hydroxyisourate hydrolase [EC:3.5.2.17] GO:0042579//microbody "GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides" GO:0051234//establishment of localization;GO:0009112 "gi|148686008|gb|EDL17955.1|/6.71346e-67/mCG22594, isoform CRA_c [Mus musculus]" 381259 1884 1.503333333 1.236666667 -0.281708247 Down 0.232633796 Tmem237 transmembrane protein 237 - GO:0031513//nonmotile primary cilium;GO:0031224//intrinsic component of membrane;GO:0031513//nonmotile primary cilium;GO:0031224//intrinsic component of membrane - GO:0016055//Wnt signaling pathway;GO:0010927;GO:0016055//Wnt signaling pathway;GO:0010927 gi|83716017|ref|NP_001028621.1|/0/transmembrane protein 237 isoform 1 [Mus musculus] 77717 1967 1.51 1.24 -0.284208429 Down 0.232633796 6030408B16Rik RIKEN cDNA 6030408B16 gene - - - - gi|74190433|dbj|BAE25895.1|/7.55393e-53/unnamed protein product [Mus musculus] 67746 1647 1.233333333 1.5 0.282399731 Up 0.232633796 4930577N17Rik RIKEN cDNA 4930577N17 gene - - - - gi|12854974|dbj|BAB30183.1|/2.08659e-75/unnamed protein product [Mus musculus] 52822 3591.74 5.52 5.006666667 -0.14081786 Down 0.232633796 Rufy3 RUN and FYVE domain containing 3 K10742|1|2e-136|490|cjo:107315722|DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12];K12482|2|5e-132|475|fch:102054796|RUN and FYVE domain-containing protein 1 GO:0043005//neuron projection;GO:0043005//neuron projection;GO:0043005//neuron projection GO:0043169//cation binding GO:0007409//axonogenesis;GO:0007409//axonogenesis;GO:0007409//axonogenesis "gi|148673405|gb|EDL05352.1|/0/RUN and FYVE domain containing 3, isoform CRA_b, partial [Mus musculus]" 20788 4570 6.316666667 6.89 0.12534054 Up 0.232614991 Srebf2 sterol regulatory element binding factor 2 K09107|1|0.0|1825|mmu:20788|sterol regulatory element-binding transcription factor 2 GO:0043005//neuron projection;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030134//ER to Golgi transport vesicle "GO:0005515//protein binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds" GO:0032844//regulation of homeostatic process;GO:0010878//cholesterol storage;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0016125//sterol metabolic process;GO:0006984//ER-nucleus signaling pathway;GO:0010038//response to metal ion;GO:0048232//male gamete generation;GO:0055094//response to lipoprotein particle;GO:0044767//single-organism developmental process;GO:0010874//regulation of cholesterol efflux gi|73661204|ref|NP_150087.1|/0/sterol regulatory element-binding protein 2 [Mus musculus] 207781 6568 6.393333333 5.823333333 -0.134723112 Down 0.232614991 C2cd2 C2 calcium-dependent domain containing 2 - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - - gi|60360478|dbj|BAD90483.1|/0/mKIAA4045 protein [Mus musculus] 81003 4258 2.13 1.816666667 -0.229559701 Down 0.232408139 Trim23 tripartite motif-containing 23 K07963|1|0.0|1135|mmu:81003|tripartite motif-containing protein 23 [EC:2.3.2.27] GO:0005764//lysosome GO:0046914//transition metal ion binding;GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0019787//ubiquitin-like protein transferase activity GO:0006486//protein glycosylation;GO:0032446//protein modification by small protein conjugation;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction "gi|148686553|gb|EDL18500.1|/0/tripartite motif protein 23, isoform CRA_b, partial [Mus musculus]" 545156 14646.4 2.08 1.77 -0.232834168 Down 0.232408139 Kalrn "kalirin, RhoGEF kinase" K15048|1|0.0|3140|mmu:545156|kalirin [EC:2.7.11.1] GO:0044297//cell body;GO:0043232;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0043232;GO:0042995//cell projection;GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0032550;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004672//protein kinase activity;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0043169//cation binding;GO:0032550;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004672//protein kinase activity;GO:0008289//lipid binding;GO:0005515//protein binding GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0010975//regulation of neuron projection development;GO:0007266//Rho protein signal transduction;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0010975//regulation of neuron projection development;GO:0007266//Rho protein signal transduction gi|295054244|ref|NP_796331.2|/0/kalirin isoform 1 [Mus musculus] 71592 7385 1.95 1.65 -0.2410081 Down 0.232379932 Pogk pogo transposable element with KRAB domain K09228|1|1e-13|83.2|pss:102447774|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0032502//developmental process;GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|219273495|ref|NP_001136420.1|/0/pogo transposable element with KRAB domain isoform 2 [Mus musculus] 109594 1022 1.673333333 1.973333333 0.237909812 Up 0.232379932 Lmo1 LIM domain only 1 K15612|1|1e-40|168|mcf:101926617|rhombotin-2 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter "gi|24659990|gb|AAH39512.1|/2.72859e-92/LIM domain only 1 (rhombotin 1), partial [Homo sapiens]" 319786 1306 0.116666667 0.253333333 1.118644496 Up 0.232370529 B930059L03Rik RIKEN cDNA B930059L03 gene - - - - - 675812 3158 0.7 0.923333333 0.399496648 Up 0.232323517 Zfp605 zinc finger protein 605 K09228|1|0.0|1454|mmu:675812|KRAB domain-containing zinc finger protein - - - gi|255683357|ref|NP_001157468.1|/0/zinc finger protein 605 [Mus musculus] 100504114 2764 0.686666667 0.903333333 0.395648514 Up 0.232323517 Gm16907 "predicted gene, 16907" K09606|1|6e-09|65.9|mmu:72061|aminopeptidase O [EC:3.4.11.-] - - - - 21408 4061 0.893333333 0.676666667 -0.400753273 Down 0.232323517 Zfp354a zinc finger protein 354A K09228|1|0.0|1204|mmu:21408|KRAB domain-containing zinc finger protein - - - - 211896 1734 0.49 0.69 0.493814613 Up 0.232304712 Depdc7 DEP domain containing 7 - - - GO:0007165//signal transduction gi|21450165|ref|NP_659053.1|/0/DEP domain-containing protein 7 [Mus musculus] 329101 2788 0.486666667 0.683333333 0.489655541 Up 0.232304712 D030040B21Rik RIKEN cDNA D030040B21 gene - - - - "gi|148682404|gb|EDL14351.1|/1.16138e-58/mCG145226, partial [Mus musculus]" 235493 4238.09 13.35 14.32666667 0.10186324 Up 0.232229493 Fam214a "family with sequence similarity 214, member A" - - - - gi|164452925|ref|NP_705812.2|/0/protein FAM214A isoform 2 [Mus musculus] 12314 1216 61.54 64.97333333 0.078323278 Up 0.232220091 Calm2 calmodulin 2 K02183|1|4e-79|297|pbi:103052604|calmodulin - - - gi|795288784|ref|XP_011821160.1|/2.78756e-93/PREDICTED: calmodulin isoform X1 [Mandrillus leucophaeus] 69459 1362.73 58.34 61.76 0.082187366 Up 0.232154274 Ubl7 ubiquitin-like 7 (bone marrow stromal cell-derived) - - - - gi|16741237|gb|AAH16456.1|/1.04987e-164/Ubiquitin-like 7 (bone marrow stromal cell-derived) [Mus musculus] 65098 1658 23.89666667 25.38666667 0.087261586 Up 0.232107262 Zfand6 "zinc finger, AN1-type domain 6" K14785|1|8e-19|97.8|dpo:Dpse_GA17094|ESF2/ABP1 family protein;K12163|2|6e-14|81.6|dre:100148477|AN1-type zinc finger and ubiquitin domain-containing protein 1 GO:0044424 GO:0046914//transition metal ion binding;GO:0043130//ubiquitin binding GO:0006915//apoptotic process;GO:0006605//protein targeting;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0034612//response to tumor necrosis factor gi|15805026|ref|NP_075361.2|/2.61642e-126/AN1-type zinc finger protein 6 [Mus musculus] 68520 1310 22.23 23.70666667 0.092784875 Up 0.232003836 Zfyve21 "zinc finger, FYVE domain containing 21" "K04679|1|3e-14|82.0|bfo:BRAFLDRAFT_91658|MAD, mothers against decapentaplegic interacting protein;K17603|3|1e-13|80.5|bmor:101744058|zinc finger FYVE domain-containing protein 1" GO:0031982//vesicle GO:0043169//cation binding - gi|326937469|ref|NP_081028.3|/4.64484e-133/zinc finger FYVE domain-containing protein 21 [Mus musculus] 67729 2405 1.496666667 1.783333333 0.252823447 Up 0.231938019 Mansc1 MANSC domain containing 1 K03068|1|6e-08|62.4|aam:106488638|low density lipoprotein receptor-related protein 5/6 GO:0031224//intrinsic component of membrane - - gi|13385846|ref|NP_080621.1|/0/MANSC domain-containing protein 1 precursor [Mus musculus] 17876 2927 1.79 1.503333333 -0.251794655 Down 0.231938019 Myef2 "myelin basic protein expression factor 2, repressor" K12887|1|3e-112|408|gfr:102040131|heterogeneous nuclear ribonucleoprotein M - - - gi|244790091|ref|NP_034982.2|/0/myelin expression factor 2 isoform 2 [Mus musculus] 545725 1357 0.616666667 0.423333333 -0.542696774 Down 0.231928617 Mterf1a mitochondrial transcription termination factor 1a "K15031|1|0.0|682|mmu:545725|transcription termination factor, mitochondrial" GO:0005759//mitochondrial matrix;GO:0005759//mitochondrial matrix GO:0043566//structure-specific DNA binding;GO:0043566//structure-specific DNA binding "GO:0000959//mitochondrial RNA metabolic process;GO:0071103//DNA conformation change;GO:0006351//transcription, DNA-templated;GO:0000959//mitochondrial RNA metabolic process;GO:0071103//DNA conformation change;GO:0006351//transcription, DNA-templated" gi|148682677|gb|EDL14624.1|/0/mCG6121 [Mus musculus] 18538 1260 23.12333333 24.59333333 0.088917904 Up 0.231834593 Pcna proliferating cell nuclear antigen K04802|1|3e-144|513|mmu:18538|proliferating cell nuclear antigen GO:0034399//nuclear periphery;GO:0043234//protein complex;GO:0005856//cytoskeleton;GO:0005657//replication fork GO:0005102//receptor binding;GO:0032404;GO:0032135//DNA insertion or deletion binding;GO:0000700;GO:0030234//enzyme regulator activity GO:0010033//response to organic substance;GO:0010038//response to metal ion;GO:0032070;GO:0044767//single-organism developmental process;GO:0006301//postreplication repair;GO:0006260//DNA replication gi|7242171|ref|NP_035175.1|/2.74301e-143/proliferating cell nuclear antigen [Mus musculus] 69524 1859 56.3 59.62333333 0.082742111 Up 0.231834593 Esam endothelial cell-specific adhesion molecule K06787|1|0.0|695|mmu:69524|endothelial cell adhesion molecule GO:0070161;GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex - GO:0016337//single organismal cell-cell adhesion gi|22094995|ref|NP_081378.1|/0/endothelial cell-selective adhesion molecule precursor [Mus musculus] 19684 4230.14 24.69 23.22 -0.088558864 Down 0.231834593 Rdx radixin K05762|1|0.0|891|ocu:100341234|radixin GO:0032155;GO:0043232;GO:0060187//cell pole;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0044425;GO:0042383//sarcolemma;GO:0005902//microvillus;GO:0032155;GO:0043232;GO:0060187//cell pole;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0044425;GO:0042383//sarcolemma;GO:0005902//microvillus;GO:0032155;GO:0043232;GO:0060187//cell pole;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0044425;GO:0042383//sarcolemma;GO:0005902//microvillus GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0008105//asymmetric protein localization;GO:0030835//negative regulation of actin filament depolymerization;GO:0030031//cell projection assembly;GO:0008105//asymmetric protein localization;GO:0030835//negative regulation of actin filament depolymerization;GO:0030031//cell projection assembly;GO:0008105//asymmetric protein localization;GO:0030835//negative regulation of actin filament depolymerization;GO:0030031//cell projection assembly gi|74224118|dbj|BAE33689.1|/0/unnamed protein product [Mus musculus] 20501 4430 59.45333333 56.13333333 -0.082899966 Down 0.231834593 Slc16a1 "solute carrier family 16 (monocarboxylic acid transporters), member 1" "K08179|1|0.0|890|mmu:20501|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 1" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0044763;GO:0006820//anion transport gi|74183928|dbj|BAE37020.1|/0/unnamed protein product [Mus musculus] 193043 1838 4.58 4.123333333 -0.151536504 Down 0.231815788 Zfp3 zinc finger protein 3 K09229|1|2e-156|555|mdo:100618319|KRAB and SCAN domains-containing zinc finger protein;K09228|5|2e-154|548|shr:100924214|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|29243904|ref|NP_808233.1|/0/zinc finger protein 3 [Mus musculus] 108903 3912 4.13 4.593333333 0.153399701 Up 0.231815788 Tbcd tubulin-specific chaperone d K12864|1|7e-129|464|bmy:Bm1_49395|beta-catenin-like protein 1;K13514|3|2e-22|111|bacu:103017657|lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-] GO:0070161;GO:0043296//apical junction complex;GO:0015630//microtubule cytoskeleton;GO:0044459 GO:0008047//enzyme activator activity;GO:0015631//tubulin binding GO:0043087//regulation of GTPase activity;GO:0006458//'de novo' protein folding;GO:0007043//cell-cell junction assembly;GO:0007162//negative regulation of cell adhesion;GO:0031111//negative regulation of microtubule polymerization or depolymerization "gi|148702895|gb|EDL34842.1|/0/tubulin-specific chaperone d, isoform CRA_b, partial [Mus musculus]" 244867 6365 4.596666667 4.136666667 -0.152119341 Down 0.231815788 Arhgap20 Rho GTPase activating protein 20 K01468|1|4e-29|134|clv:102098075|imidazolonepropionase [EC:3.5.2.7];K18470|2|1e-24|119|xla:446344|Rho GTPase-activating protein 1 GO:0044464 GO:0008047//enzyme activator activity;GO:0017016//Ras GTPase binding;GO:0008289//lipid binding GO:0007266//Rho protein signal transduction gi|47575840|ref|NP_780744.2|/0/rho GTPase-activating protein 20 [Mus musculus] 70155 4844 4.763333333 4.303333333 -0.146516916 Down 0.231815788 Ogfrl1 opioid growth factor receptor-like 1 - - - - gi|124487293|ref|NP_001074548.1|/0/opioid growth factor receptor-like protein 1 [Mus musculus] 76432 737 1.03 0.8 -0.364572432 Down 0.231787581 2310001H17Rik RIKEN cDNA 2310001H17 gene - - - - - 665001 946 0.256666667 0.426666667 0.733213459 Up 0.231749972 Gm14391 predicted gene 14391 K09228|1|5e-31|137|mmu:626832|KRAB domain-containing zinc finger protein - - - "gi|150010536|ref|NP_001092778.1|/0/KRAB box and zinc finger, C2H2 type domain containing isoform 1 [Mus musculus]" 227099 3077 0.35 0.533333333 0.607682577 Up 0.231608936 Pms1 postmeiotic segregation increased 1 (S. cerevisiae) K10864|1|0.0|1710|mmu:227099|DNA mismatch repair protein PMS1 - - - - 226043 1979.26 3.566666667 3.993333333 0.163017112 Up 0.231571326 Cbwd1 COBW domain containing 1 K10591|1|4e-07|59.3|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26];K02870|2|2e-06|57.4|cjc:103793914|large subunit ribosomal protein L12e - GO:0032550;GO:0032550 - gi|22122605|ref|NP_666209.1|/0/COBW domain-containing protein 1 [Mus musculus] 56469 3855 5.766666667 6.33 0.134467868 Up 0.231552522 Pias1 protein inhibitor of activated STAT 1 K04706|1|0.0|1149|mmu:56469|E3 SUMO-protein ligase PIAS1 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003676//nucleic acid binding;GO:0019787//ubiquitin-like protein transferase activity GO:0006366//transcription from RNA polymerase II promoter;GO:0048232//male gamete generation;GO:0016925//protein sumoylation;GO:0034622//cellular macromolecular complex assembly;GO:0051145//smooth muscle cell differentiation gi|31543478|ref|NP_062637.2|/0/E3 SUMO-protein ligase PIAS1 [Mus musculus] 66938 1948.2 6.046666667 6.606666667 0.127782507 Up 0.231552522 Sh3d21 SH3 domain containing 21 K12470|1|3e-16|89.4|dre:793623|SH3 domain-containing kinase-binding protein 1;K13738|4|1e-15|87.4|acs:103280695|CD2-associated protein - - - gi|242117962|ref|NP_001156005.1|/0/SH3 domain-containing protein 21 isoform 1 [Mus musculus] 70599 5109 6.426666667 5.863333333 -0.132349569 Down 0.231552522 Ssfa2 sperm specific antigen 2 - GO:0044424;GO:0016020//membrane - - gi|194473671|ref|NP_542125.3|/0/sperm-specific antigen 2 homolog [Mus musculus] 18753 2790 7.85 7.206666667 -0.123360537 Down 0.231514912 Prkcd "protein kinase C, delta" K06068|1|0.0|1373|mmu:18753|novel protein kinase C delta type [EC:2.7.11.13] GO:0034399//nuclear periphery;GO:0030054//cell junction;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0004713//protein tyrosine kinase activity;GO:0030234//enzyme regulator activity;GO:0004697//protein kinase C activity;GO:0019900//kinase binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0043169//cation binding GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0043405//regulation of MAP kinase activity;GO:0042113//B cell activation;GO:0006470//protein dephosphorylation;GO:0010828//positive regulation of glucose transport;GO:0032411//positive regulation of transporter activity;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0019724//B cell mediated immunity;GO:0006952//defense response;GO:0001933//negative regulation of protein phosphorylation;GO:0007569//cell aging;GO:0015740//C4-dicarboxylate transport;GO:0046513//ceramide biosynthetic process;GO:0002274;GO:0012502//induction of programmed cell death;GO:0006974//cellular response to DNA damage stimulus;GO:0000302//response to reactive oxygen species;GO:0001101//response to acid chemical;GO:0009267//cellular response to starvation;GO:0009968//negative regulation of signal transduction;GO:0030041//actin filament polymerization;GO:0009746;GO:0006680//glucosylceramide catabolic process;GO:0044259//multicellular organismal macromolecule metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0031345//negative regulation of cell projection organization;GO:0097305//response to alcohol;GO:0006685//sphingomyelin catabolic process;GO:0008286//insulin receptor signaling pathway;GO:0001816//cytokine production gi|893548269|ref|NP_001297611.1|/0/protein kinase C delta type isoform 1 [Mus musculus] 78903 2642 7.493333333 8.133333333 0.118239112 Up 0.231514912 Wrnip1 Werner helicase interacting protein 1 K07478|1|0.0|1167|mmu:78903|putative ATPase GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding;GO:0043169//cation binding GO:0009154//purine ribonucleotide catabolic process;GO:0006270//DNA replication initiation;GO:0006281//DNA repair gi|254540120|ref|NP_084491.3|/0/ATPase WRNIP1 [Mus musculus] 215723 2085 0.21 0.373333333 0.830074999 Up 0.23150551 Mfsd6l major facilitator superfamily domain containing 6-like - GO:0031224//intrinsic component of membrane - GO:0044763 gi|22122467|ref|NP_666116.1|/0/major facilitator superfamily domain-containing protein 6-like [Mus musculus] 12750 1909.75 13.75 12.79 -0.104415354 Down 0.231477303 Clk4 CDC like kinase 4 K08823|1|0.0|673|mmu:12750|CDC-like kinase [EC:2.7.12.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity GO:0006468//protein phosphorylation;GO:0008380//RNA splicing;GO:0006468//protein phosphorylation;GO:0008380//RNA splicing gi|755537242|ref|XP_011247010.1|/0/PREDICTED: dual specificity protein kinase CLK4 isoform X1 [Mus musculus] 56298 3648.78 13.93 12.97 -0.103016778 Down 0.231477303 Atl2 atlastin GTPase 2 K17339|1|0.0|909|mmu:56298|atlastin [EC:3.6.5.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0051259//protein oligomerization;GO:0006996//organelle organization;GO:0051259//protein oligomerization;GO:0006996//organelle organization "gi|148706549|gb|EDL38496.1|/0/ADP-ribosylation factor-like 6 interacting protein 2, isoform CRA_b, partial [Mus musculus]" 14827 2658 53.64 56.86333333 0.084189435 Up 0.231458498 Pdia3 protein disulfide isomerase associated 3 "K08056|1|0.0|944|mmu:14827|protein disulfide isomerase family A, member 3 [EC:5.3.4.1]" GO:0044432;GO:0048770 GO:0005488//binding;GO:0015036//disulfide oxidoreductase activity GO:0019725//cellular homeostasis;GO:0006915//apoptotic process;GO:0018904 gi|74228706|dbj|BAE21849.1|/0/unnamed protein product [Mus musculus] 18704 8042 0.953333333 0.73 -0.385084277 Down 0.231439693 Pik3c2a "phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide" K00923|1|0.0|3256|mmu:18704|phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154] - - - gi|145279206|ref|NP_035213.2|/0/phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [Mus musculus] 67602 2393 9.633333333 10.39 0.109088662 Up 0.231392681 Necap1 NECAP endocytosis associated 1 K20069|1|4e-132|474|mmu:67602|adaptin ear-binding coat-associated protein 1/2 GO:0012505//endomembrane system;GO:0031982//vesicle;GO:0030118//clathrin coat - GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport gi|27229051|ref|NP_080543.2|/3.26322e-131/adaptin ear-binding coat-associated protein 1 [Mus musculus] 77134 2678 22.35 23.78666667 0.089878283 Up 0.231355072 Hnrnpa0 heterogeneous nuclear ribonucleoprotein A0 K12894|1|1e-90|337|mmu:77134|heterogeneous nuclear ribonucleoprotein A0 - - - - 80890 7108 0.92 1.156666667 0.330267396 Up 0.231336267 Trim2 tripartite motif-containing 2 K11997|1|0.0|1535|cge:100772337|tripartite motif-containing protein 2/3 GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0042981//regulation of apoptotic process;GO:0042981//regulation of apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0042981//regulation of apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0042981//regulation of apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0042981//regulation of apoptotic process;GO:0032446//protein modification by small protein conjugation gi|411147443|ref|NP_109631.2|/0/tripartite motif-containing protein 2 isoform 3 [Mus musculus] 667803 1289 1.193333333 0.95 -0.328997668 Down 0.231336267 C920025E04Rik "histocompatibility 2, T region locus, pseudogene" "K06751|1|0.0|651|mmu:667803|major histocompatibility complex, class I" GO:0031224//intrinsic component of membrane;GO:0042611 - GO:0002488;GO:0043583//ear development gi|401871063|ref|NP_001257934.1|/0/H-2 class I histocompatibility antigen-like precursor [Mus musculus] 17060 2097 0.936666667 1.173333333 0.325005298 Up 0.231336267 Blnk B cell linker K07371|1|0.0|874|mmu:17060|B-cell linker protein GO:0044444//cytoplasmic part;GO:0016020//membrane "GO:0030674//protein binding, bridging" GO:0006952//defense response;GO:0030098//lymphocyte differentiation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0006955//immune response "gi|148709900|gb|EDL41846.1|/0/B-cell linker, isoform CRA_a, partial [Mus musculus]" 75480 757 0.2 0.07 -1.514573173 Down 0.231336267 1700003F12Rik RIKEN cDNA 1700003F12 gene - - - - "gi|148674137|gb|EDL06084.1|/8.34567e-94/mCG3690, isoform CRA_b, partial [Mus musculus]" 109284 1821 58.07333333 61.25666667 0.076991018 Up 0.231298657 R3hdm4 R3H domain containing 4 K13373|1|2e-12|76.6|hro:HELRODRAFT_194195|17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270] GO:0043231//intracellular membrane-bounded organelle GO:0097159//organic cyclic compound binding - gi|66392583|ref|NP_818775.2|/1.51899e-114/R3H domain-containing protein 4 [Mus musculus] 98682 4770 5.37 4.866666667 -0.141988125 Down 0.23127045 Mfsd6 major facilitator superfamily domain containing 6 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0044763;GO:0044763 "gi|148667563|gb|EDK99979.1|/0/RIKEN cDNA 2210010L05, partial [Mus musculus]" 23876 5893 5.316666667 4.82 -0.141488872 Down 0.23127045 Fbln5 fibulin 5 K17340|1|0.0|911|mmu:23876|fibulin 5 GO:0044420//extracellular matrix component;GO:0044424;GO:0044421 GO:0046872//metal ion binding;GO:0005515//protein binding GO:0085029//extracellular matrix assembly;GO:0022610;GO:0016049//cell growth;GO:0034613//cellular protein localization;GO:0090322//regulation of superoxide metabolic process gi|6753824|ref|NP_035942.1|/0/fibulin-5 precursor [Mus musculus] 75826 4499 4.87 5.373333333 0.141895566 Up 0.23127045 Senp2 SUMO/sentrin specific peptidase 2 K03345|1|0.0|1020|mmu:75826|sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68] GO:0031982//vesicle;GO:0016604//nuclear body;GO:0005635//nuclear envelope;GO:0031982//vesicle;GO:0016604//nuclear body;GO:0005635//nuclear envelope GO:0005515//protein binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0005515//protein binding;GO:0019783//ubiquitin-like protein-specific protease activity GO:0007166//cell surface receptor signaling pathway;GO:0050658//RNA transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0043393//regulation of protein binding;GO:0009798//axis specification;GO:0045184//establishment of protein localization;GO:0035561//regulation of chromatin binding;GO:0044767//single-organism developmental process;GO:0070646//protein modification by small protein removal;GO:0007166//cell surface receptor signaling pathway;GO:0050658//RNA transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0043393//regulation of protein binding;GO:0009798//axis specification;GO:0045184//establishment of protein localization;GO:0035561//regulation of chromatin binding;GO:0044767//single-organism developmental process;GO:0070646//protein modification by small protein removal gi|13386400|ref|NP_083733.1|/0/sentrin-specific protease 2 [Mus musculus] 243373 3573 0.203333333 0.36 0.824150165 Up 0.231167024 AI854703 expressed sequence AI854703 K09228|1|2e-51|207|fch:102056845|KRAB domain-containing zinc finger protein - - - - 75273 3463 13.37 14.32333333 0.099367811 Up 0.231091805 Pelp1 "proline, glutamic acid and leucine rich protein 1" "K16913|1|0.0|1253|mmu:75273|proline-, glutamic acid- and leucine-rich protein 1" - - - - 11937 3486 0.266666667 0.433333333 0.700439718 Up 0.231007183 Atp2a1 "ATPase, Ca++ transporting, cardiac muscle, fast twitch 1" "K05853|1|0.0|1868|cge:100763714|Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]" GO:0005789//endoplasmic reticulum membrane;GO:0031672//A band;GO:0031224//intrinsic component of membrane GO:0032550;GO:0015215//nucleotide transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0046872//metal ion binding;GO:0042802//identical protein binding GO:0006937//regulation of muscle contraction;GO:0051560//mitochondrial calcium ion homeostasis;GO:0051646//mitochondrion localization;GO:0090075//relaxation of muscle;GO:0006915//apoptotic process;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0034976//response to endoplasmic reticulum stress;GO:0031443//fast-twitch skeletal muscle fiber contraction;GO:0009154//purine ribonucleotide catabolic process;GO:0070588//calcium ion transmembrane transport;GO:0009725//response to hormone "gi|148685413|gb|EDL17360.1|/0/ATPase, Ca++ transporting, cardiac muscle, fast twitch 1, isoform CRA_d, partial [Mus musculus]" 13655 3799 0.44 0.27 -0.704544116 Down 0.231007183 Egr3 early growth response 3 K12497|1|0.0|810|mmu:13655|early growth response protein 3 - - - - 217031 2119 3.24 3.636666667 0.166622883 Up 0.231007183 Tada2a transcriptional adaptor 2A K11314|1|0.0|887|mmu:217031|transcriptional adapter 2-alpha GO:0070461//SAGA-type complex;GO:0005819//spindle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0008080//N-acetyltransferase activity "GO:0006351//transcription, DNA-templated;GO:0090311//regulation of protein deacetylation;GO:0016575//histone deacetylation;GO:0006468//protein phosphorylation;GO:0010608//posttranscriptional regulation of gene expression;GO:0000087//mitotic M phase;GO:0016573//histone acetylation" gi|27369796|ref|NP_766150.1|/0/transcriptional adapter 2-alpha [Mus musculus] 381836 1139 3.28 3.683333333 0.167316149 Up 0.231007183 Sbk2 "SH3-binding domain kinase family, member 2" K08858|1|1e-166|588|mmu:381836|serine/threonine-protein kinase SBK [EC:2.7.11.1] - - - gi|568946085|ref|XP_006540201.1|/1.97133e-174/PREDICTED: serine/threonine-protein kinase SBK2 isoform X2 [Mus musculus] 245536 751 0.206666667 0.073333333 -1.494764692 Down 0.230978976 Gm614 predicted gene 614 - - - - - 594844 1129 0.196666667 0.07 -1.490325627 Down 0.230978976 Tceal3 transcription elongation factor A (SII)-like 3 - - - - - 20887 1444 53.41333333 56.50333333 0.081136059 Up 0.230969574 Sult1a1 "sulfotransferase family 1A, phenol-preferring, member 1" K01014|1|3e-148|527|mmu:20887|aryl sulfotransferase [EC:2.8.2.1] GO:0044444//cytoplasmic part GO:0032550;GO:0042802//identical protein binding;GO:0008146//sulfotransferase activity GO:0006790//sulfur compound metabolic process;GO:0009698//phenylpropanoid metabolic process;GO:0009712//catechol-containing compound metabolic process;GO:0031960//response to corticosteroid;GO:0008202//steroid metabolic process;GO:0008015//blood circulation gi|19526822|ref|NP_598431.1|/2.91261e-147/sulfotransferase 1A1 [Mus musculus] 14248 4069.87 59.17333333 56.09666667 -0.07703212 Down 0.230931964 Flii flightless I actin binding protein K03178|1|0.0|1661|chx:102190674|ubiquitin-activating enzyme E1 [EC:6.2.1.45];K05768|2|5e-69|266|xtr:100495760|gelsolin;K05761|3|1e-68|264|xma:102235025|villin 1 - - - - 245522 2236 0.51 0.71 0.477321778 Up 0.23087555 Zc4h2 "zinc finger, C4H2 domain containing" K20478|1|2e-06|57.0|dre:557772|golgin subfamily B member 1 - GO:0043169//cation binding;GO:0043169//cation binding;GO:0043169//cation binding - gi|345807532|ref|XP_549040.3|/5.79313e-104/PREDICTED: zinc finger C4H2 domain-containing protein isoform X1 [Canis lupus familiaris] 20700 1808.74 0.696666667 0.5 -0.478540442 Down 0.23087555 Serpina1a "serine (or cysteine) peptidase inhibitor, clade A, member 1A" K03984|1|0.0|791|mmu:20700|alpha-1-antitrypsin - - - gi|357588427|ref|NP_001239498.1|/0/alpha-1-antitrypsin 1-1 isoform 2 [Mus musculus] 105404 2308 0.71 0.51 -0.477321778 Down 0.23087555 BB123696 expressed sequence BB123696 K04507|1|8e-10|45.8|ssc:100519266|calcyclin binding protein - - - "gi|149044984|gb|EDL98070.1|/1.40819e-14/rCG44081, isoform CRA_a [Rattus norvegicus]" 14841 2818 0.38 0.216666667 -0.810522201 Down 0.230866148 Gsg2 "germ cell associated 2, haspin" K16315|1|0.0|1355|mmu:14841|serine/threonine-protein kinase haspin [EC:2.7.11.1] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0035184//histone threonine kinase activity;GO:0003676//nucleic acid binding GO:0035556//intracellular signal transduction;GO:0000070//mitotic sister chromatid segregation;GO:0034502//protein localization to chromosome;GO:1901976//regulation of cell cycle checkpoint;GO:0072355//histone H3-T3 phosphorylation gi|62298072|sp|Q9Z0R0.3|HASP_MOUSE/0/RecName: Full=Serine/threonine-protein kinase haspin; AltName: Full=Germ cell-specific gene 2 protein; AltName: Full=Haploid germ cell-specific nuclear protein kinase 16485 8970 0.356666667 0.533333333 0.580461108 Up 0.230837941 Kcna1 "potassium voltage-gated channel, shaker-related subfamily, member 1" K04874|1|0.0|847|mmu:16485|potassium voltage-gated channel Shaker-related subfamily A member 1 - - - gi|119395752|ref|NP_034725.3|/0/potassium voltage-gated channel subfamily A member 1 [Mus musculus] 17829 2243 0.35 0.526666667 0.589535231 Up 0.230837941 Muc1 "mucin 1, transmembrane" "K06568|1|0.0|861|mmu:17829|mucin 1, transmembrane" GO:0044424;GO:0044459 "GO:0005515//protein binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000989//transcription factor activity, transcription factor binding" "GO:0044703;GO:0032526//response to retinoic acid;GO:0006915//apoptotic process;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0035066//positive regulation of histone acetylation" gi|7305293|ref|NP_038633.1|/0/mucin-1 precursor [Mus musculus] 67586 1577 0.353333333 0.53 0.584962501 Up 0.230837941 Ubxn11 UBX domain protein 11 - GO:0043232;GO:0043232 - - gi|568931779|ref|XP_006539183.1|/0/PREDICTED: UBX domain-containing protein 11 isoform X1 [Mus musculus] 627049 3895 0.526666667 0.35 -0.589535231 Down 0.230837941 Zfp800 zinc finger protein 800 K19325|1|2e-08|65.1|cmk:103188183|zinc finger protein 592;K09228|2|8e-08|62.8|spu:100890837|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|568939738|ref|XP_006505206.1|/0/PREDICTED: zinc finger protein 800 isoform X2 [Mus musculus] 75986 1404 0.073333333 0.203333333 1.471305719 Up 0.230809733 Agmat agmatine ureohydrolase (agmatinase) K01480|1|0.0|676|mmu:75986|agmatinase [EC:3.5.3.11] GO:0043231//intracellular membrane-bounded organelle "GO:0043169//cation binding;GO:0016813//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines" GO:0006525//arginine metabolic process;GO:0006596//polyamine biosynthetic process;GO:1901162 "gi|124487169|ref|NP_001074877.1|/0/agmatinase, mitochondrial precursor [Mus musculus]" 110312 748 0.073333333 0.203333333 1.471305719 Up 0.230809733 Pmch pro-melanin-concentrating hormone K05229|1|4e-89|329|mmu:110312|pro-melanin-concentrating hormone GO:0043231//intracellular membrane-bounded organelle;GO:0044421 GO:0031776;GO:0005179//hormone activity "GO:0007186//G-protein coupled receptor signaling pathway;GO:0033500//carbohydrate homeostasis;GO:0007589//body fluid secretion;GO:0001963//synaptic transmission, dopaminergic;GO:0048167//regulation of synaptic plasticity;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0042320//regulation of circadian sleep/wake cycle, REM sleep;GO:0008217//regulation of blood pressure" gi|71361678|ref|NP_084247.1|/2.99015e-88/pro-MCH preproprotein [Mus musculus] 12929 5050 7.713333333 7.086666667 -0.122247268 Down 0.230753319 Crkl v-crk avian sarcoma virus CT10 oncogene homolog-like K04438|1|4e-171|605|mmu:12929|proto-oncogene C-crk - - - - 270066 7043 24.17 22.76 -0.086716915 Down 0.230753319 Slc35e1 "solute carrier family 35, member E1" "K15283|1|0.0|697|mmu:270066|solute carrier family 35, member E1" GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization gi|148678855|gb|EDL10802.1|/0/hypothetical protein 6030458H05 [Mus musculus] 333433 4393 23.49 22.08333333 -0.08908876 Down 0.230753319 Gpd1l glycerol-3-phosphate dehydrogenase 1-like K00006|1|0.0|698|mmu:333433|glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8] GO:0016020//membrane;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0048037//cofactor binding;GO:0000166//nucleotide binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0016247//channel regulator activity" GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0003254//regulation of membrane depolarization;GO:0001933//negative regulation of protein phosphorylation;GO:0019674//NAD metabolic process;GO:0006072//glycerol-3-phosphate metabolic process;GO:0048522;GO:0006641//triglyceride metabolic process;GO:0002028//regulation of sodium ion transport;GO:0046473//phosphatidic acid metabolic process "gi|22902419|gb|AAH37729.1|/0/Gpd1l protein, partial [Mus musculus]" 67549 1765 7.95 7.32 -0.119111212 Down 0.230753319 Gpr89 G protein-coupled receptor 89 - GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane GO:0005244//voltage-gated ion channel activity GO:0045184//establishment of protein localization;GO:0006820//anion transport;GO:0008544//epidermis development;GO:0045851//pH reduction;GO:0034220//ion transmembrane transport "gi|148706980|gb|EDL38927.1|/0/G protein-coupled receptor 89, isoform CRA_c, partial [Mus musculus]" 24015 3813 14.18666667 13.24666667 -0.098906278 Down 0.230706307 Abce1 "ATP-binding cassette, sub-family E (OABP), member 1" "K06174|1|0.0|1129|tup:102469036|ATP-binding cassette, sub-family E, member 1" GO:0043231//intracellular membrane-bounded organelle GO:0017111//nucleoside-triphosphatase activity;GO:0043169//cation binding;GO:0032550;GO:0051536//iron-sulfur cluster binding;GO:0004857//enzyme inhibitor activity GO:0051707//response to other organism;GO:0016070//RNA metabolic process;GO:0009154//purine ribonucleotide catabolic process gi|537200957|gb|ERE79301.1|/0/ATP-binding cassette sub-family E member 1 [Cricetulus griseus] 67416 3672.62 2.983333333 2.62 -0.18735837 Down 0.2306781 Armcx2 "armadillo repeat containing, X-linked 2" - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|50510505|dbj|BAD32238.1|/0/mKIAA0512 protein [Mus musculus] 231571 2419.74 2.943333333 2.58 -0.190079872 Down 0.2306781 Rpap2 RNA polymerase II associated protein 2 - GO:0044451;GO:0044451;GO:0044451;GO:0044451;GO:0044451 GO:0043169//cation binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0043169//cation binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0043169//cation binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0043169//cation binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0043169//cation binding;GO:0004722//protein serine/threonine phosphatase activity GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter gi|254540043|ref|NP_659160.2|/0/putative RNA polymerase II subunit B1 CTD phosphatase Rpap2 isoform A [Mus musculus] 14084 4452 20.94 22.34 0.093367744 Up 0.230631088 Faf1 Fas-associated factor 1 K18726|1|9e-120|434|tca:664346|FAS-associated factor 2 GO:0005789//endoplasmic reticulum membrane GO:0032182//ubiquitin-like protein binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0008134//transcription factor binding;GO:0019900//kinase binding GO:0007155//cell adhesion;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0006461//protein complex assembly;GO:0009894;GO:0006915//apoptotic process gi|795440944|ref|XP_011762462.1|/0/PREDICTED: FAS-associated factor 1 [Macaca nemestrina] 106512 1359 5.82 6.373333333 0.131028964 Up 0.230612283 Gpsm3 "G-protein signalling modulator 3 (AGS3-like, C. elegans)" K15838|1|1e-40|170|mmu:106512|G-protein signaling modulator 3 - - - gi|74226720|dbj|BAE27009.1|/3.61422e-43/unnamed protein product [Mus musculus] 380836 2161 6.266666667 5.716666667 -0.132524086 Down 0.230612283 Mrs2 MRS2 magnesium transporter K16075|1|0.0|813|mmu:380836|magnesium transporter GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046873//metal ion transmembrane transporter activity GO:0070838//divalent metal ion transport "gi|511094010|ref|NP_001013407.2|/0/magnesium transporter MRS2 homolog, mitochondrial precursor [Mus musculus]" 68272 4201 6.213333333 5.666666667 -0.132867114 Down 0.230612283 Rbm28 RNA binding motif protein 28 K14573|1|0.0|1225|mmu:68272|nucleolar protein 4 GO:0043231//intracellular membrane-bounded organelle GO:0097159//organic cyclic compound binding - gi|166235127|ref|NP_598686.2|/0/RNA-binding protein 28 [Mus musculus] 71706 2421 6 6.546666667 0.125798023 Up 0.230612283 Slc46a3 "solute carrier family 46, member 3" "K14613|1|0.0|880|mmu:71706|MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1/3" GO:0031224//intrinsic component of membrane - GO:0044763 "gi|148673895|gb|EDL05842.1|/0/RIKEN cDNA 1200006F02, partial [Mus musculus]" 77422 2416 6.526666667 5.976666667 -0.127005277 Down 0.230612283 C330018D20Rik RIKEN cDNA C330018D20 gene K00626|1|7e-17|92.0|cqu:CpipJ_CPIJ019232|acetyl-CoA C-acetyltransferase [EC:2.3.1.9] GO:0043231//intracellular membrane-bounded organelle - GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy gi|256773197|ref|NP_084185.1|/5.75401e-59/glutaredoxin-like protein C5orf63 homolog [Mus musculus] 435965 4007 6.526666667 5.976666667 -0.127005277 Down 0.230612283 Lrp3 low density lipoprotein receptor-related protein 3 K20050|1|0.0|1535|mmu:435965|low-density lipoprotein receptor-related protein 3/10/12 GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane - GO:0016192//vesicle-mediated transport gi|148539563|ref|NP_001019878.1|/0/low-density lipoprotein receptor-related protein 3 precursor [Mus musculus] 66059 547.31 49.91 52.9 0.083938818 Up 0.230555869 Krtcap2 keratinocyte associated protein 2 - GO:0005789//endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane - GO:0006487//protein N-linked glycosylation;GO:0006487//protein N-linked glycosylation gi|55777844|gb|AAH43030.1|/1.45744e-52/Krtcap2 protein [Mus musculus] 623474 3805.47 0.073333333 0.2 1.447458977 Up 0.230490052 Rad54b RAD54 homolog B (S. cerevisiae) K10877|1|6e-63|246|ptg:102965968|DNA repair and recombination protein RAD54B [EC:3.6.4.-] GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0005488//binding "GO:0009314//response to radiation;GO:0009154//purine ribonucleotide catabolic process;GO:0000725//recombinational repair;GO:0042221//response to chemical;GO:0006351//transcription, DNA-templated" gi|371502134|ref|NP_001243071.1|/3.24924e-77/fibrinogen silencer-binding protein [Mus musculus] 100038709 4591 0.076666667 0.21 1.453717967 Up 0.230490052 Gm10789 predicted gene 10789 "K04565|1|2e-06|58.5|bom:102279265|superoxide dismutase, Cu-Zn family [EC:1.15.1.1]" - - - gi|694980606|ref|XP_009449370.1|/6.34671e-44/PREDICTED: uncharacterized protein LOC104006808 [Pan troglodytes] 30960 1658 51.57333333 54.54 0.080689406 Up 0.230471248 Vapa "vesicle-associated membrane protein, associated protein A" K06096|1|4e-132|474|mmu:30960|vesicle-associated membrane protein-associated protein A GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane GO:0060089;GO:0046983//protein dimerization activity GO:0030030//cell projection organization;GO:0033365//protein localization to organelle;GO:0006665//sphingolipid metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|94721328|ref|NP_038961.2|/3.528e-131/vesicle-associated membrane protein-associated protein A [Mus musculus] 17476 4348 2.833333333 3.213333333 0.181570305 Up 0.230461845 Mpeg1 macrophage expressed gene 1 - GO:0031224//intrinsic component of membrane - - "gi|148709523|gb|EDL41469.1|/0/mCG55704, partial [Mus musculus]" 19258 4707 0.85 0.636666667 -0.416924609 Down 0.230386626 Ptpn4 "protein tyrosine phosphatase, non-receptor type 4" K18037|1|0.0|1896|mmu:19258|tyrosine-protein phosphatase non-receptor type 4 [EC:3.1.3.48] GO:0044459;GO:0043232 GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|117320548|ref|NP_064317.2|/0/tyrosine-protein phosphatase non-receptor type 4 [Mus musculus] 101056073 2059 0.276666667 0.133333333 -1.053111336 Down 0.230377224 LOC101056073 zinc finger protein 501-like K09228|1|0.0|1122|mmu:626316|KRAB domain-containing zinc finger protein - - - - 171285 2725 0.13 0.27 1.054447784 Up 0.230377224 Havcr2 hepatitis A virus cellular receptor 2 K20414|1|1e-121|440|mmu:171285|hepatitis A virus cellular receptor 2 GO:0031224//intrinsic component of membrane - - gi|45385110|gb|AAS59531.1|/1.03953e-120/T-cell immunoglobulin mucin [Mus musculus] 433771 2574.45 51.92333333 48.97 -0.084484807 Down 0.230358419 Minos1 mitochondrial inner membrane organizing system 1 K17784|1|2e-25|120|mmu:433771|mitochondrial inner membrane organizing system protein 1 - - - "gi|148681348|gb|EDL13295.1|/4.74252e-59/mCG145204, partial [Mus musculus]" 24069 4525 4.073333333 4.523333333 0.151176436 Up 0.230349017 Sufu suppressor of fused homolog (Drosophila) K06229|1|0.0|986|cge:100753058|suppressor of fused GO:0031981//nuclear lumen;GO:0005929//cilium;GO:0031981//nuclear lumen;GO:0005929//cilium GO:0019900//kinase binding;GO:0060089;GO:0003712//transcription cofactor activity;GO:0019900//kinase binding GO:0042992//negative regulation of transcription factor import into nucleus;GO:0014020;GO:0008544//epidermis development;GO:0006366//transcription from RNA polymerase II promoter;GO:0021520//spinal cord motor neuron cell fate specification;GO:0021521//ventral spinal cord interneuron specification;GO:0009855//determination of bilateral symmetry;GO:0003143//embryonic heart tube morphogenesis;GO:0031397//negative regulation of protein ubiquitination;GO:0045879//negative regulation of smoothened signaling pathway;GO:0045879//negative regulation of smoothened signaling pathway;GO:0014020;GO:0021520//spinal cord motor neuron cell fate specification;GO:0021521//ventral spinal cord interneuron specification;GO:0031397//negative regulation of protein ubiquitination;GO:0008544//epidermis development;GO:0001649//osteoblast differentiation;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0044092//negative regulation of molecular function;GO:0006366//transcription from RNA polymerase II promoter;GO:0003143//embryonic heart tube morphogenesis;GO:0009855//determination of bilateral symmetry gi|625292290|ref|XP_007637899.1|/0/PREDICTED: suppressor of fused homolog isoform X3 [Cricetulus griseus] 53611 4599 4.553333333 4.106666667 -0.148955228 Down 0.230349017 Vti1a vesicle transport through interaction with t-SNAREs 1A K08493|1|4e-88|329|mmu:53611|vesicle transport through interaction with t-SNAREs 1 GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0044297//cell body;GO:0008021//synaptic vesicle;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0044297//cell body;GO:0008021//synaptic vesicle;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0044297//cell body;GO:0008021//synaptic vesicle;GO:0012505//endomembrane system GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0006906//vesicle fusion;GO:0016482//cytosolic transport;GO:0015031//protein transport;GO:0006906//vesicle fusion;GO:0016482//cytosolic transport;GO:0015031//protein transport;GO:0006906//vesicle fusion;GO:0016482//cytosolic transport;GO:0015031//protein transport "gi|148669787|gb|EDL01734.1|/6.34979e-99/vesicle transport through interaction with t-SNAREs homolog 1A (yeast), isoform CRA_e, partial [Mus musculus]" 69538 5280 2.076666667 2.403333333 0.210767096 Up 0.230349017 Antxr1 anthrax toxin receptor 1 "K06238|1|1e-10|72.8|pbi:103065903|collagen, type VI, alpha" GO:0030027//lamellipodium;GO:0031224//intrinsic component of membrane;GO:0030175//filopodium GO:0043169//cation binding;GO:0003779//actin binding;GO:0038023//signaling receptor activity GO:0000904//cell morphogenesis involved in differentiation;GO:0000003//reproduction;GO:0030036//actin cytoskeleton organization gi|113205504|ref|NP_001037714.1|/0/anthrax toxin receptor 1 [Rattus norvegicus] 241041 1180 0.716666667 0.516666667 -0.472068444 Down 0.230320809 Gm4956 predicted gene 4956 K00799|1|7e-92|229|rno:363205|glutathione S-transferase [EC:2.5.1.18] - - - - 104776 3420 53.44 50.51 -0.081350966 Down 0.230302005 Aldh6a1 "aldehyde dehydrogenase family 6, subfamily A1" K00140|1|0.0|1001|mmu:104776|malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] - - - - 11287 4681 0.273333333 0.136666667 -1 Down 0.2302832 Pzp pregnancy zone protein K03910|1|0.0|1623|pale:102895501|alpha-2-macroglobulin - - - - 68270 2821 0.833333333 1.063333333 0.351628329 Up 0.230254993 Dnaaf1 "dynein, axonemal assembly factor 1" "K19750|1|0.0|1206|mmu:68270|dynein assembly factor 1, axonemal" GO:0016020//membrane;GO:0005930//axoneme GO:0005515//protein binding GO:0030323//respiratory tube development;GO:0003002//regionalization;GO:0070286//axonemal dynein complex assembly;GO:0001889//liver development;GO:0007368//determination of left/right symmetry;GO:0042384//cilium assembly;GO:0003352//regulation of cilium movement "gi|13386136|ref|NP_080924.1|/0/dynein assembly factor 1, axonemal [Mus musculus]" 433926 2841 1.08 0.846666667 -0.351165316 Down 0.230254993 Lrrc8b "leucine rich repeat containing 8 family, member B" K19613|1|1e-30|138|bfo:BRAFLDRAFT_214464|leucine-rich repeat protein SHOC2 GO:0031224//intrinsic component of membrane - - gi|60360308|dbj|BAD90398.1|/0/mKIAA0231 protein [Mus musculus] 224805 3368 12.4 13.33333333 0.104697379 Up 0.230254993 Aars2 "alanyl-tRNA synthetase 2, mitochondrial" K01872|1|0.0|1842|mmu:224805|alanyl-tRNA synthetase [EC:6.1.1.7] - - - - 70036 1036 0.723333333 0.94 0.37800012 Up 0.230236188 Dancr differentiation antagonizing non-protein coding RNA - - - - - 17937 2593 4.666666667 5.153333333 0.143113492 Up 0.230179774 Nab2 Ngfi-A binding protein 2 - GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0005515//protein binding GO:0008366//axon ensheathment;GO:0006383//transcription from RNA polymerase III promoter;GO:0008544//epidermis development;GO:0036075;GO:0007422//peripheral nervous system development gi|171543864|ref|NP_001116367.1|/0/NGFI-A-binding protein 2 isoform 2 [Mus musculus] 11496 9175.06 0.98 1.223333333 0.319963908 Up 0.23008575 Adam22 a disintegrin and metallopeptidase domain 22 K16068|1|0.0|1698|mmu:11496|disintegrin and metalloproteinase domain-containing protein 22 [EC:3.4.24.-] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane "GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding" GO:0007626//locomotory behavior;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0014044//Schwann cell development;GO:0007626//locomotory behavior;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0014044//Schwann cell development;GO:0007626//locomotory behavior;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0014044//Schwann cell development;GO:0007626//locomotory behavior;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0014044//Schwann cell development;GO:0007626//locomotory behavior;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0014044//Schwann cell development gi|882939059|ref|NP_001297368.1|/0/disintegrin and metalloproteinase domain-containing protein 22 isoform 4 precursor [Mus musculus] 665155 3286 10.29 9.553333333 -0.107166873 Down 0.23008575 Srp54b signal recognition particle 54B K03106|1|0.0|963|ptg:102957830|signal recognition particle subunit SRP54 [EC:3.6.5.4] GO:0048500//signal recognition particle;GO:0016604//nuclear body GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0003723//RNA binding;GO:0005048//signal sequence binding GO:0042221//response to chemical;GO:0010467//gene expression;GO:0009154//purine ribonucleotide catabolic process;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0019538//protein metabolic process gi|410962045|ref|XP_003987587.1|/0/PREDICTED: signal recognition particle 54 kDa protein isoform X1 [Felis catus] 68379 2823.16 21.44333333 22.81666667 0.089558853 Up 0.230038738 Ciz1 CDKN1A interacting zinc finger protein 1 K04650|1|6e-09|65.9|aga:AgaP_AGAP004734|nuclear receptor co-repressor 1;K04585|4|6e-09|65.9|cmk:103173223|parathyroid hormone receptor 1 - GO:0043169//cation binding;GO:0005515//protein binding;GO:0043169//cation binding;GO:0005515//protein binding;GO:0043169//cation binding;GO:0005515//protein binding;GO:0043169//cation binding;GO:0005515//protein binding;GO:0043169//cation binding;GO:0005515//protein binding GO:0006270//DNA replication initiation;GO:0051647//nucleus localization;GO:0006270//DNA replication initiation;GO:0051647//nucleus localization;GO:0006270//DNA replication initiation;GO:0051647//nucleus localization;GO:0006270//DNA replication initiation;GO:0051647//nucleus localization;GO:0006270//DNA replication initiation;GO:0051647//nucleus localization "gi|148676594|gb|EDL08541.1|/0/CDKN1A interacting zinc finger protein 1, isoform CRA_b, partial [Mus musculus]" 81898 6192 23.49 22.12333333 -0.08647794 Down 0.230038738 Sf3b1 "splicing factor 3b, subunit 1" K12828|1|0.0|2603|ecb:100070506|splicing factor 3B subunit 1 GO:0005681//spliceosomal complex;GO:0016604//nuclear body GO:0005488//binding GO:0003002//regionalization;GO:0000377 gi|511905488|ref|XP_004772218.1|/0/PREDICTED: splicing factor 3B subunit 1 isoform X1 [Mustela putorius furo] 66300 1697 6.893333333 7.51 0.123611128 Up 0.229954116 Inafm1 InaF motif containing 1 - - - - gi|210147464|ref|NP_001129742.1|/2.97202e-08/putative transmembrane protein INAFM1 [Mus musculus] 50911 1622 7.496666667 8.12 0.115230472 Up 0.229954116 Exosc9 exosome component 9 K03678|1|0.0|710|mmu:50911|exosome complex component RRP45 GO:0000178//exosome (RNase complex);GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0003723//RNA binding;GO:0008408//3'-5' exonuclease activity "GO:0016075//rRNA catabolic process;GO:0016049//cell growth;GO:0002376//immune system process;GO:0042254//ribosome biogenesis;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" gi|9506981|ref|NP_062266.1|/0/exosome complex component RRP45 [Mus musculus] 17149 692 21.95333333 20.59666667 -0.092029138 Down 0.229878897 Magoh "mago homolog, exon junction complex core component" K12877|1|3e-81|303|tup:102484886|protein mago nashi GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding GO:0006366//transcription from RNA polymerase II promoter;GO:0006412//translation;GO:0006397//mRNA processing;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0000377;GO:0007276//gamete generation;GO:0006405//RNA export from nucleus gi|533170162|ref|XP_005398616.1|/1.34716e-81/PREDICTED: protein mago nashi homolog isoform X1 [Chinchilla lanigera] 54644 4144.16 13.25666667 12.34 -0.103375667 Down 0.229822483 Otud5 OTU domain containing 5 K12655|1|0.0|792|cfa:480911|OTU domain-containing protein 5 [EC:3.4.19.12] - - - - 224833 5032 0.383333333 0.22 -0.801095932 Down 0.229813081 AI661453 expressed sequence AI661453 K08618|1|5e-09|67.0|mze:101478756|a disintegrin and metalloproteinase with thrombospondin motifs 2 [EC:3.4.24.14];K10491|3|2e-08|65.5|mgp:104917069|zinc finger and BTB domain-containing protein 4 - - - gi|161484644|ref|NP_663464.2|/0/uncharacterized protein C6orf132 homolog [Mus musculus] 19049 2017 0.21 0.366666667 0.80407979 Up 0.229813081 Ppp1r1b "protein phosphatase 1, regulatory (inhibitor) subunit 1B" K15494|1|4e-81|305|mmu:19049|protein phosphatase 1 regulatory subunit 1B - - - - 23918 1632 20.00666667 21.36 0.094430829 Up 0.229775471 Impdh2 inosine 5'-phosphate dehydrogenase 2 K00088|1|0.0|978|mmu:23918|IMP dehydrogenase [EC:1.1.1.205] GO:0044439 "GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0036094//small molecule binding" GO:0009152//purine ribonucleotide biosynthetic process;GO:0032943//mononuclear cell proliferation;GO:0051260//protein homooligomerization;GO:0070670//response to interleukin-4 gi|664729904|ref|XP_008522151.1|/0/PREDICTED: inosine-5'-monophosphate dehydrogenase 2 isoform X2 [Equus przewalskii] 76357 1669 21.65666667 20.31 -0.092620965 Down 0.229775471 Trmt5 TRM5 tRNA methyltransferase 5 K15429|1|0.0|1002|mmu:76357|tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] GO:0043231//intracellular membrane-bounded organelle GO:0009019//tRNA (guanine-N1-)-methyltransferase activity GO:0006399//tRNA metabolic process;GO:0001510//RNA methylation "gi|148704565|gb|EDL36512.1|/0/TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae), isoform CRA_b, partial [Mus musculus]" 66881 4291 22.52 21.17 -0.089185558 Down 0.229775471 Pcyox1 prenylcysteine oxidase 1 K05906|1|0.0|964|mmu:66881|prenylcysteine oxidase / farnesylcysteine lyase [EC:1.8.3.5 1.8.3.6] GO:0034385;GO:0000323//lytic vacuole;GO:0016020//membrane "GO:0016670//oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor;GO:0015662//ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism" GO:0019941//modification-dependent protein catabolic process;GO:0015698//inorganic anion transport;GO:0000098//sulfur amino acid catabolic process gi|13385294|ref|NP_080099.1|/0/prenylcysteine oxidase precursor [Mus musculus] 12503 1485.24 2.153333333 1.846666667 -0.221648189 Down 0.22969085 Cd247 CD247 antigen "K06453|1|8e-77|291|mmu:12503|CD3Z antigen, zeta polypeptide" GO:0042101//T cell receptor complex;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0042101//T cell receptor complex;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0042101//T cell receptor complex;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0042101//T cell receptor complex;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0042101//T cell receptor complex;GO:0031224//intrinsic component of membrane;GO:0044424 GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity GO:0050851//antigen receptor-mediated signaling pathway;GO:0050851//antigen receptor-mediated signaling pathway;GO:0050851//antigen receptor-mediated signaling pathway;GO:0050851//antigen receptor-mediated signaling pathway;GO:0050851//antigen receptor-mediated signaling pathway gi|164664502|ref|NP_001106863.1|/3.95675e-96/CD247 antigen isoform iota precursor [Mus musculus] 101197 2776 1.22 1.48 0.278716028 Up 0.229625033 Zfp956 zinc finger protein 956 K09228|1|0.0|1134|mmu:101197|KRAB domain-containing zinc finger protein GO:0044464 GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|242332561|ref|NP_849229.2|/0/uncharacterized protein LOC101197 [Mus musculus] 76003 1340 0.526666667 0.726666667 0.464403577 Up 0.229606228 Tmem150cos "transmembrane protein 150C, opposite strand" - - - - "gi|148688357|gb|EDL20304.1|/9.95386e-38/mCG145977, partial [Mus musculus]" 331532 1016 0.083333333 0.213333333 1.35614381 Up 0.229578021 Tceal5 transcription elongation factor A (SII)-like 5 K02910|1|1e-06|56.2|bacu:102998004|large subunit ribosomal protein L31e - - "GO:0006351//transcription, DNA-templated" "gi|148691903|gb|EDL23850.1|/4.75673e-97/transcription elongation factor A (SII)-like 5, partial [Mus musculus]" 100043910 1859 9.296666667 10.03 0.109536172 Up 0.229559216 A630075F10Rik RIKEN cDNA A630075F10 gene - GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - GO:0032446//protein modification by small protein conjugation;GO:0032446//protein modification by small protein conjugation "gi|148674628|gb|EDL06575.1|/2.46082e-43/mCG145905, partial [Mus musculus]" 14782 2692 9.656666667 10.39 0.10559847 Up 0.229559216 Gsr glutathione reductase K00383|1|0.0|925|mmu:14782|glutathione reductase (NADPH) [EC:1.8.1.7] - - - "gi|160298213|ref|NP_034474.4|/0/glutathione reductase, mitochondrial precursor [Mus musculus]" 102580 2741.4 4.12 3.696666667 -0.156419378 Down 0.229549814 Alg9 "asparagine-linked glycosylation 9 (alpha 1,2 mannosyltransferase)" "K03846|1|0.0|800|mmu:102580|alpha-1,2-mannosyltransferase [EC:2.4.1.259 2.4.1.261]" GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane "GO:0000026//alpha-1,2-mannosyltransferase activity;GO:0000026//alpha-1,2-mannosyltransferase activity" GO:0006497//protein lipidation;GO:0006497//protein lipidation "gi|568958632|ref|XP_006509966.1|/0/PREDICTED: alpha-1,2-mannosyltransferase ALG9 isoform X3 [Mus musculus]" 228829 5752 3.656666667 4.076666667 0.156860878 Up 0.229549814 Phf20 PHD finger protein 20 K18402|1|0.0|1895|mmu:228829|PHD finger protein 20 GO:0044665//MLL1/2 complex;GO:0005635//nuclear envelope GO:0010485//H4 histone acetyltransferase activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0043967//histone H4 acetylation;GO:0006351//transcription, DNA-templated" gi|124487307|ref|NP_766262.2|/0/PHD finger protein 20 [Mus musculus] 17341 3494 0.043333333 0.16 1.884522783 Up 0.2294934 Bhlha15 "basic helix-loop-helix family, member a15" K08040|1|2e-60|237|mmu:17341|class B basic helix-loop-helix protein 8 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0042802//identical protein binding GO:0048311//mitochondrion distribution;GO:0019932//second-messenger-mediated signaling;GO:0007166//cell surface receptor signaling pathway;GO:0006816//calcium ion transport;GO:0021700//developmental maturation;GO:0006366//transcription from RNA polymerase II promoter;GO:0033500//carbohydrate homeostasis gi|568938963|ref|XP_006504871.1|/1.30476e-86/PREDICTED: class A basic helix-loop-helix protein 15 isoform X1 [Mus musculus] 20871 1168 0.17 0.046666667 -1.86507042 Down 0.2294934 Aurkc aurora kinase C K11480|1|3e-162|573|mmu:20871|aurora kinase C [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0005819//spindle;GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0005819//spindle;GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0005819//spindle GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity GO:0000087//mitotic M phase;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0000087//mitotic M phase;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0000087//mitotic M phase;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process "gi|148699387|gb|EDL31334.1|/0/mCG116173, isoform CRA_b, partial [Mus musculus]" 116870 2775 44.95666667 47.68333333 0.084950022 Up 0.2294934 Mta1 metastasis associated 1 K11660|1|0.0|1324|mmu:116870|metastasis-associated protein MTA GO:0000118//histone deacetylase complex GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding "GO:0006351//transcription, DNA-templated;GO:0016050//vesicle organization" gi|91598896|ref|NP_473422.2|/0/metastasis-associated protein MTA1 [Mus musculus] 22793 2620.61 52.00666667 49.27666667 -0.077791904 Down 0.2294934 Zyx zyxin K06273|1|0.0|659|mmu:22793|zyxin GO:0005912//adherens junction;GO:0005912//adherens junction;GO:0044424;GO:0005912//adherens junction;GO:0044424;GO:0005912//adherens junction GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - "gi|149065434|gb|EDM15510.1|/0/zyxin, isoform CRA_a [Rattus norvegicus]" 20747 2882 45.32 48.04 0.08408829 Up 0.229446388 Spop speckle-type POZ protein K10523|1|0.0|720|pale:102883440|speckle-type POZ protein GO:0031461//cullin-RING ubiquitin ligase complex;GO:0016604//nuclear body GO:0044389//ubiquitin-like protein ligase binding GO:0016567//protein ubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process "gi|148684035|gb|EDL15982.1|/0/speckle-type POZ protein, isoform CRA_b, partial [Mus musculus]" 23912 2143 0.226666667 0.39 0.782901878 Up 0.229333559 Rhof ras homolog family member F (in filopodia) "K07872|1|4e-102|375|mmu:23912|Ras homolog gene family, member F" GO:0043232;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0009154//purine ribonucleotide catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0030036//actin cytoskeleton organization gi|28201958|ref|NP_780301.1|/3.07525e-101/rho-related GTP-binding protein RhoF precursor [Mus musculus] 74316 868 47.46 50.15333333 0.079633489 Up 0.229314754 Isca2 iron-sulfur cluster assembly 2 K13628|1|4e-11|70.9|hmg:100201724|iron-sulfur cluster assembly protein - - - - 70356 1622 52.39333333 49.70666667 -0.075943892 Down 0.229314754 St13 suppression of tumorigenicity 13 K09560|1|5e-141|503|mmu:70356|suppressor of tumorigenicity protein 13 GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part GO:0031072//heat shock protein binding;GO:0032558//adenyl deoxyribonucleotide binding GO:0042026//protein refolding;GO:0051259//protein oligomerization gi|74177941|dbj|BAE29766.1|/4.03465e-140/unnamed protein product [Mus musculus] 60411 1222 0.163333333 0.046666667 -1.807354922 Down 0.229277145 Cenpk centromere protein K K11503|1|1e-130|469|mmu:60411|centromere protein K "GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region" GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter gi|30840994|ref|NP_851406.1|/1.12651e-129/centromere protein K isoform 2 [Mus musculus] 54351 1435.24 22.69666667 21.38 -0.086218579 Down 0.22922073 Elp5 elongator acetyltransferase complex subunit 5 - - - - - 244962 3112 7.083333333 7.69 0.118555163 Up 0.229089097 Snx14 sorting nexin 14 K17926|1|0.0|1842|mmu:244962|sorting nexin-14 GO:0031224//intrinsic component of membrane GO:0005543//phospholipid binding GO:0045184//establishment of protein localization;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway gi|568961513|ref|XP_006511246.1|/0/PREDICTED: sorting nexin-14 isoform X1 [Mus musculus] 72607 4686 51.19666667 48.56333333 -0.076182432 Down 0.229051487 Usp13 ubiquitin specific peptidase 13 (isopeptidase T-3) K11836|1|0.0|1649|mmu:72607|ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12] - GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0032182//ubiquitin-like protein binding "GO:0019941//modification-dependent protein catabolic process;GO:0044699;GO:0031647//regulation of protein stability;GO:0006351//transcription, DNA-templated;GO:0016579//protein deubiquitination;GO:0006914//autophagy" gi|61316410|ref|NP_001013042.1|/0/ubiquitin carboxyl-terminal hydrolase 13 [Mus musculus] 53312 3290.87 20.97333333 22.28333333 0.08740889 Up 0.22902328 Nub1 negative regulator of ubiquitin-like proteins 1 - - - - - 16478 2894 47.23666667 44.62 -0.082216649 Down 0.228995073 Jund jun D proto-oncogene K04449|1|7e-115|417|rno:24518|transcription factor jun-D GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0005102//receptor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0043566//structure-specific DNA binding;GO:0005102//receptor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0043566//structure-specific DNA binding GO:0048511//rhythmic process;GO:0009605//response to external stimulus;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0051592//response to calcium ion;GO:0044767//single-organism developmental process;GO:0009314//response to radiation;GO:0002237//response to molecule of bacterial origin;GO:0009725//response to hormone;GO:0048511//rhythmic process;GO:0009605//response to external stimulus;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0051592//response to calcium ion;GO:0044767//single-organism developmental process;GO:0009314//response to radiation;GO:0002237//response to molecule of bacterial origin;GO:0009725//response to hormone gi|20302045|ref|NP_620230.1|/5.93412e-114/transcription factor jun-D isoform JunD-FL [Rattus norvegicus] 58203 1357.08 3.123333333 3.516666667 0.171122046 Up 0.228957464 Zbp1 Z-DNA binding protein 1 K12965|1|5e-161|570|rno:171091|Z-DNA binding protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0004000//adenosine deaminase activity;GO:0043566//structure-specific DNA binding GO:0006952//defense response;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0002252 gi|213417964|ref|NP_001132991.1|/1.12226e-104/Z-DNA-binding protein 1 isoform 2 [Mus musculus] 215008 11399.84 3.6 3.21 -0.165423609 Down 0.228957464 Vezt "vezatin, adherens junctions transmembrane protein" - GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0002141//stereocilia ankle link;GO:0070161;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0002141//stereocilia ankle link;GO:0070161 GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0009792//embryo development ending in birth or egg hatching;GO:0007155//cell adhesion;GO:0009792//embryo development ending in birth or egg hatching;GO:0007155//cell adhesion gi|752993374|ref|NP_001291504.1|/0/vezatin isoform 3 [Mus musculus] 67419 2748 3.136666667 3.523333333 0.167708749 Up 0.228957464 3632451O06Rik RIKEN cDNA 3632451O06 gene K10802|1|4e-52|209|mcc:713250|high mobility group protein B1;K04574|2|3e-07|60.1|obi:106879116|neurofilament heavy polypeptide;K17582|3|4e-07|59.7|nvi:100120806|antigen KI-67 - - - gi|148747539|ref|NP_080418.2|/0/uncharacterized protein C14orf37 homolog precursor [Mus musculus] 67702 2440 3.193333333 3.586666667 0.167580517 Up 0.228957464 Rnf149 ring finger protein 149 K15704|1|0.0|694|mmu:67702|E3 ubiquitin-protein ligase RNF149 [EC:2.3.2.27] - - - gi|224809379|ref|NP_001028307.2|/0/E3 ubiquitin-protein ligase RNF149 precursor [Mus musculus] 791073 76 5.053333333 4.573333333 -0.143989272 Down 0.228938659 Mir762 microRNA 762 - - - - - 380614 6387 4.753333333 5.233333333 0.138790577 Up 0.228938659 Intu inturned planar cell polarity protein - - - - - 14479 11526.45 5.396666667 4.913333333 -0.135366461 Down 0.228938659 Usp15 ubiquitin specific peptidase 15 K11835|1|0.0|1888|mmu:14479|ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.4.19.12] - - - - 50723 2748 5.13 4.65 -0.14172811 Down 0.228938659 Icosl icos ligand K06710|1|1e-163|580|mmu:50723|inducible T-cell co-stimulator ligand GO:0016021//integral component of membrane;GO:0009986//cell surface GO:0005488//binding GO:0042097;GO:0042102//positive regulation of T cell proliferation;GO:0007154//cell communication;GO:0002204//somatic recombination of immunoglobulin genes involved in immune response gi|7657220|ref|NP_056605.1|/8.4837e-163/ICOS ligand precursor [Mus musculus] 77782 7732 0.996666667 0.773333333 -0.366020679 Down 0.228929256 Polq "polymerase (DNA directed), theta" K02349|1|0.0|4732|mmu:77782|DNA polymerase theta [EC:2.7.7.7] - - - - 638247 3162 9.45 10.16666667 0.105460508 Up 0.228854037 9530082P21Rik RIKEN cDNA 9530082P21 gene - - - - - 56309 1485 9.416666667 10.13333333 0.105820456 Up 0.228854037 Mycbp MYC binding protein K00934|1|2e-09|66.6|dme:Dmel_CG4546|arginine kinase [EC:2.7.3.3] - - - gi|589969665|ref|XP_006997309.1|/5.67274e-61/PREDICTED: c-Myc-binding protein [Peromyscus maniculatus bairdii] 217127 5949.55 8.85 9.566666667 0.112338876 Up 0.228854037 Kat7 K(lysine) acetyltransferase 7 K11307|1|0.0|1114|mmu:217127|histone acetyltransferase MYST2 [EC:2.3.1.48] GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0008080//N-acetyltransferase activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0008080//N-acetyltransferase activity;GO:0046914//transition metal ion binding;GO:0008080//N-acetyltransferase activity "GO:0043967//histone H4 acetylation;GO:0006259//DNA metabolic process;GO:0006351//transcription, DNA-templated;GO:0043967//histone H4 acetylation;GO:0006259//DNA metabolic process;GO:0006351//transcription, DNA-templated;GO:0043967//histone H4 acetylation;GO:0006259//DNA metabolic process;GO:0006351//transcription, DNA-templated" "gi|148684025|gb|EDL15972.1|/0/MYST histone acetyltransferase 2, isoform CRA_b, partial [Mus musculus]" 19345 1925.66 47.93333333 50.52 0.075825369 Up 0.228807025 Rab5c "RAB5C, member RAS oncogene family" K07889|1|5e-105|384|mmu:19345|Ras-related protein Rab-5C "GO:0016020//membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0006996//organelle organization;GO:0006897//endocytosis;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction "gi|148670589|gb|EDL02536.1|/3.38435e-123/RAB5C, member RAS oncogene family, isoform CRA_b, partial [Mus musculus]" 68845 1118.72 19.76333333 21.06333333 0.091907469 Up 0.228788221 Pih1d1 PIH1 domain containing 1 "K12302|1|4e-21|104|cmy:102947352|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8;K19751|2|2e-08|62.8|lgi:LOTGIDRAFT_123979|dynein assembly factor 2, axonemal" GO:0030529//intracellular ribonucleoprotein complex;GO:0030529//intracellular ribonucleoprotein complex;GO:0030529//intracellular ribonucleoprotein complex - GO:0000491//small nucleolar ribonucleoprotein complex assembly;GO:0000491//small nucleolar ribonucleoprotein complex assembly;GO:0000491//small nucleolar ribonucleoprotein complex assembly gi|21313052|ref|NP_083682.1|/9.58838e-144/PIH1 domain-containing protein 1 [Mus musculus] 71805 2928 5.816666667 6.343333333 0.125048525 Up 0.228769416 Nup93 nucleoporin 93 K14309|1|0.0|1540|mmu:71805|nuclear pore complex protein Nup93 GO:0005635//nuclear envelope;GO:0031981//nuclear lumen GO:0005198//structural molecule activity GO:0050658//RNA transport;GO:0006999//nuclear pore organization;GO:0045184//establishment of protein localization "gi|148679173|gb|EDL11120.1|/0/nucleoporin 93, isoform CRA_a, partial [Mus musculus]" 77619 724 6.196666667 5.67 -0.128143629 Down 0.228769416 Prelid2 PRELI domain containing 2 - GO:0043231//intracellular membrane-bounded organelle - - gi|113931158|ref|NP_084218.1|/1.63764e-96/PRELI domain-containing protein 2 [Mus musculus] 54151 2984.4 48.08666667 45.53333333 -0.078713845 Down 0.228647185 Cyhr1 cysteine and histidine rich 1 - GO:0012505//endomembrane system;GO:0044424;GO:0012505//endomembrane system;GO:0044424;GO:0012505//endomembrane system;GO:0044424;GO:0012505//endomembrane system;GO:0044424;GO:0012505//endomembrane system;GO:0044424;GO:0012505//endomembrane system;GO:0044424;GO:0012505//endomembrane system;GO:0044424 GO:0046914//transition metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0046872//metal ion binding GO:0032446//protein modification by small protein conjugation;GO:0032446//protein modification by small protein conjugation gi|444741673|ref|NP_001263250.1|/0/cysteine and histidine-rich protein 1 isoform 3 [Mus musculus] 69080 1528 20.57 21.86 0.087751607 Up 0.228637783 Gmppa GDP-mannose pyrophosphorylase A K00966|1|0.0|827|mmu:69080|mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] GO:0044444//cytoplasmic part GO:0032550;GO:0008905//mannose-phosphate guanylyltransferase activity GO:0009226//nucleotide-sugar biosynthetic process;GO:0006487//protein N-linked glycosylation gi|19526884|ref|NP_598469.1|/0/mannose-1-phosphate guanyltransferase alpha [Mus musculus] 56420 1332 19.01666667 20.30666667 0.094689055 Up 0.228637783 Ppp4c "protein phosphatase 4, catalytic subunit" K15423|1|0.0|636|shr:100933379|serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0008287//protein serine/threonine phosphatase complex;GO:0016020//membrane GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0035556//intracellular signal transduction;GO:0007010//cytoskeleton organization;GO:0006464//cellular protein modification process;GO:0000018//regulation of DNA recombination;GO:0006796//phosphate-containing compound metabolic process "gi|440907053|gb|ELR57245.1|/0/Serine/threonine-protein phosphatase 4 catalytic subunit, partial [Bos mutus]" 66257 2103 12.56 13.44666667 0.098412119 Up 0.228618978 Nicn1 nicolin 1 K16607|1|4e-121|437|mmu:66257|nicolin-1 GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle - - gi|13384852|ref|NP_079725.1|/3.79124e-120/nicolin-1 [Mus musculus] 73744 3221 13.96 13.06666667 -0.095407788 Down 0.228618978 Man2c1 "mannosidase, alpha, class 2C, member 1" K01191|1|0.0|1959|mmu:73744|alpha-mannosidase [EC:3.2.1.24] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0015923//mannosidase activity GO:0019318//hexose metabolic process gi|30794150|ref|NP_082912.1|/0/alpha-mannosidase 2C1 [Mus musculus] 14388 4909.49 12.86333333 13.75 0.096167075 Up 0.228618978 Gab1 growth factor receptor bound protein 2-associated protein 1 K09593|1|0.0|1354|mmu:14388|GRB2-associated-binding protein 1 GO:0044424;GO:0044424 GO:0060089;GO:0008289//lipid binding;GO:0060089;GO:0008289//lipid binding GO:0009888//tissue development;GO:0038127//ERBB signaling pathway;GO:0001892//embryonic placenta development;GO:0019221//cytokine-mediated signaling pathway;GO:0006950//response to stress;GO:0016477//cell migration;GO:0000187//activation of MAPK activity;GO:0009888//tissue development;GO:0038127//ERBB signaling pathway;GO:0001892//embryonic placenta development;GO:0019221//cytokine-mediated signaling pathway;GO:0006950//response to stress;GO:0016477//cell migration;GO:0000187//activation of MAPK activity gi|669633282|ref|NP_001288227.1|/0/GRB2-associated-binding protein 1 isoform 1 [Mus musculus] 211007 3493 11.9 12.78666667 0.103678646 Up 0.228618978 Trim41 tripartite motif-containing 41 K12017|1|0.0|991|mmu:211007|tripartite motif-containing protein 41 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003824//catalytic activity - gi|795310627|ref|XP_011925412.1|/0/PREDICTED: E3 ubiquitin-protein ligase TRIM41 isoform X1 [Cercocebus atys] 242521 4217 13.68666667 12.8 -0.096627317 Down 0.228618978 Klhl9 kelch-like 9 K10447|1|0.0|1238|mmu:242521|kelch-like protein 9/13 - - - - 16873 2736 0.31 0.163333333 -0.924448967 Down 0.228543759 Lhx5 LIM homeobox protein 5 K18493|1|0.0|639|rno:124451|LIM homeobox protein 5 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0007267//cell-cell signaling;GO:0021533//cell differentiation in hindbrain;GO:0008283//cell proliferation;GO:0021872//forebrain generation of neurons;GO:0021543//pallium development;GO:0022037//metencephalon development;GO:0021515//cell differentiation in spinal cord" gi|6678690|ref|NP_032525.1|/1.53087e-180/LIM/homeobox protein Lhx5 [Mus musculus] 67303 1137 0.31 0.163333333 -0.924448967 Down 0.228543759 3110045C21Rik RIKEN cDNA 3110045C21 gene - - - - "gi|148707218|gb|EDL39165.1|/6.1765e-43/mCG145609, isoform CRA_a, partial [Mus musculus]" 319481 5111 2.886666667 2.533333333 -0.188367606 Down 0.228534356 Wdr59 WD repeat domain 59 K20409|1|0.0|1931|mmu:319481|WD repeat-containing protein 59 - - - gi|50511187|dbj|BAD32579.1|/0/mKIAA1923 protein [Mus musculus] 230145 2216 0.09 0.223333333 1.311201688 Up 0.228496747 Galnt12 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 K00710|1|0.0|1066|mmu:230145|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008376//acetylgalactosaminyltransferase activity GO:0006493//protein O-linked glycosylation gi|27370010|ref|NP_766281.1|/0/polypeptide N-acetylgalactosaminyltransferase 12 [Mus musculus] 69147 610 0.09 0.223333333 1.311201688 Up 0.228496747 2200002J24Rik RIKEN cDNA 2200002J24 gene K01542|1|2e-13|77.8|ggo:101138827|H+/K+-exchanging ATPase alpha polypeptide [EC:3.6.3.10] GO:0031224//intrinsic component of membrane - - "gi|148692050|gb|EDL23997.1|/1.43987e-56/RIKEN cDNA 2200002J24, isoform CRA_b, partial [Mus musculus]" 58206 1783 0.223333333 0.38 0.766800824 Up 0.228487344 Zbtb32 zinc finger and BTB domain containing 32 K10506|1|0.0|886|mmu:58206|zinc finger and BTB domain-containing protein 32 GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0048534//hematopoietic or lymphoid organ development;GO:0042110//T cell activation;GO:0006351//transcription, DNA-templated;GO:0001816//cytokine production" gi|134032011|ref|NP_067372.2|/0/zinc finger and BTB domain-containing protein 32 [Mus musculus] 246198 7271 21.16 19.87666667 -0.090263791 Down 0.228459137 Mllt6 "myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6" K05175|1|6e-102|376|ocu:100339376|gamma-aminobutyric acid receptor subunit alpha;K11348|2|5e-40|170|cmk:103176610|bromodomain and PHD finger-containing protein 1 - - - gi|118130868|ref|NP_647472.2|/0/protein AF-17 [Mus musculus] 76516 764 2.8 3.173333333 0.180572246 Up 0.228459137 2010001A14Rik RIKEN cDNA 2010001A14 gene - - - - - 226101 7133 1.366666667 1.116666667 -0.291462814 Down 0.228365113 Myof myoferlin K18261|1|0.0|2281|pbi:103067154|dysferlin - - - gi|693582864|ref|NP_001289069.1|/0/myoferlin isoform 1 [Mus musculus] 19889 4422 1.373333333 1.12 -0.294183104 Down 0.228365113 Rp2 retinitis pigmentosa 2 homolog K18272|1|0.0|665|mmu:19889|protein XRP2 GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle "GO:0032550;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032550;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032550;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032550;GO:0008047//enzyme activator activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032550;GO:0008047//enzyme activator activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0043087//regulation of GTPase activity;GO:0009209;GO:0032989;GO:0006457//protein folding;GO:0009152//purine ribonucleotide biosynthetic process;GO:0050953//sensory perception of light stimulus;GO:0045184//establishment of protein localization;GO:0009132//nucleoside diphosphate metabolic process;GO:0043087//regulation of GTPase activity;GO:0009209;GO:0032989;GO:0006457//protein folding;GO:0009152//purine ribonucleotide biosynthetic process;GO:0050953//sensory perception of light stimulus;GO:0045184//establishment of protein localization;GO:0009132//nucleoside diphosphate metabolic process;GO:0043087//regulation of GTPase activity;GO:0009209;GO:0032989;GO:0006457//protein folding;GO:0009152//purine ribonucleotide biosynthetic process;GO:0050953//sensory perception of light stimulus;GO:0045184//establishment of protein localization;GO:0009132//nucleoside diphosphate metabolic process;GO:0043087//regulation of GTPase activity;GO:0009209;GO:0009152//purine ribonucleotide biosynthetic process;GO:0045184//establishment of protein localization;GO:0009132//nucleoside diphosphate metabolic process;GO:0043087//regulation of GTPase activity;GO:0009209;GO:0009152//purine ribonucleotide biosynthetic process;GO:0045184//establishment of protein localization;GO:0009132//nucleoside diphosphate metabolic process "gi|148668431|gb|EDL00755.1|/0/retinitis pigmentosa 2 homolog (human), isoform CRA_c [Mus musculus]" 71093 2355 12.65 13.53 0.097024454 Up 0.228318101 Atoh8 atonal bHLH transcription factor 8 K09084|1|3e-134|481|mmu:71093|atonal protein 8 - - - - 70527 2157 6.666666667 7.263333333 0.123666196 Up 0.228186468 Stambp STAM binding protein K11866|1|0.0|741|mmu:70527|STAM-binding protein [EC:3.4.19.12] GO:0031981//nuclear lumen;GO:0032155;GO:0016020//membrane GO:0043169//cation binding;GO:0019783//ubiquitin-like protein-specific protease activity GO:0006915//apoptotic process;GO:0007154//cell communication;GO:0070646//protein modification by small protein removal "gi|148666675|gb|EDK99091.1|/0/Stam binding protein, isoform CRA_d, partial [Mus musculus]" 21353 2018.86 7.096666667 7.7 0.117716902 Up 0.228186468 Tank TRAF family member-associated Nf-kappa B activator K12650|1|0.0|872|mmu:21353|TRAF family member-associated NF-kappa-B activator GO:0044424;GO:0044424;GO:0044424 GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding - gi|6755718|ref|NP_035659.1|/0/TRAF family member-associated NF-kappa-B activator isoform 3 [Mus musculus] 230972 2717 0.18 0.056666667 -1.667424661 Down 0.228120651 Arhgef16 Rho guanine nucleotide exchange factor (GEF) 16 K13744|1|1e-144|516|gga:429163|Rho guanine nucleotide exchange factor 26 GO:0044424 GO:0005102//receptor binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0017016//Ras GTPase binding;GO:0019904//protein domain specific binding;GO:0008289//lipid binding GO:0051130//positive regulation of cellular component organization;GO:0006935//chemotaxis gi|74148934|dbj|BAE32151.1|/0/unnamed protein product [Mus musculus] 93878 3506 0.056666667 0.176666667 1.640457613 Up 0.228120651 Pcdhb7 protocadherin beta 7 K16494|1|0.0|1533|mmu:93878|protocadherin beta GO:0031224//intrinsic component of membrane - GO:0016337//single organismal cell-cell adhesion gi|148613874|ref|NP_444362.3|/0/protocadherin beta 7 [Mus musculus] 100169874 1026 0.056666667 0.18 1.667424661 Up 0.228120651 Gm11110 predicted gene 11110 - - - - - 99890 2651.47 2.056666667 2.373333333 0.206606752 Up 0.22799842 Prmt6 protein arginine N-methyltransferase 6 K11437|1|0.0|716|mmu:99890|type I protein arginine methyltransferase [EC:2.1.1.319] - - - - 76961 627 0.833333333 0.626666667 -0.411195433 Down 0.227970213 2210420H20Rik RIKEN cDNA 2210420H20 gene K10591|1|6e-06|52.8|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034728//nucleosome organization "gi|148677432|gb|EDL09379.1|/1.95537e-51/mCG144592, partial [Mus musculus]" 70466 3154 0.653333333 0.466666667 -0.485426827 Down 0.227829177 Ckap2l cytoskeleton associated protein 2-like K16769|1|0.0|1424|mmu:70466|cytoskeleton-associated protein 2 GO:0005815//microtubule organizing center - - "gi|148696286|gb|EDL28233.1|/0/cytoskeleton associated protein 2-like, isoform CRA_a, partial [Mus musculus]" 52530 1004 11.91 12.78333333 0.102090664 Up 0.227819775 Nhp2 NHP2 ribonucleoprotein K11129|1|1e-79|298|mmu:52530|H/ACA ribonucleoprotein complex subunit 2 GO:0016604//nuclear body;GO:0030529//intracellular ribonucleoprotein complex GO:0003723//RNA binding GO:0000154//rRNA modification gi|13386120|ref|NP_080907.1|/9.76113e-79/H/ACA ribonucleoprotein complex subunit 2 [Mus musculus] 66464 1353 20.47 21.72333333 0.085734392 Up 0.227782166 Taf12 TATA-box binding protein associated factor 12 K03126|1|2e-101|372|bacu:103004276|transcription initiation factor TFIID subunit 12 GO:0070461//SAGA-type complex;GO:0005667//transcription factor complex "GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0008080//N-acetyltransferase activity;GO:0008135//translation factor activity, RNA binding;GO:0046983//protein dimerization activity" GO:0006412//translation;GO:0044093;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter gi|521031440|gb|EPQ13226.1|/2.00545e-110/Transcription initiation factor TFIID subunit 12 [Myotis brandtii] 223648 2301 0.563333333 0.766666667 0.444610615 Up 0.227688142 Ccdc166 coiled-coil domain containing 166 K19603|1|3e-36|103|asn:102378924|mitogen-activated protein kinase 15 [EC:2.7.11.24];K16069|3|3e-06|56.6|ptg:102969926|disintegrin and metalloproteinase domain-containing protein 29 [EC:3.4.24.-] - - - gi|242332551|ref|NP_666171.2|/0/coiled-coil domain-containing protein 166 isoform 1 [Mus musculus] 231646 4631 5.573333333 6.09 0.127901787 Up 0.227622325 Myo1h myosin 1H K10356|1|0.0|2034|mmu:231646|myosin I - - - gi|755513635|ref|XP_011246497.1|/0/PREDICTED: unconventional myosin-Ih isoform X1 [Mus musculus] 75580 7824 9.85 9.15 -0.106351981 Down 0.227575313 Zbtb4 zinc finger and BTB domain containing 4 K10491|1|0.0|1250|mmu:75580|zinc finger and BTB domain-containing protein 4 - - - gi|50510977|dbj|BAD32474.1|/0/mKIAA1538 protein [Mus musculus] 74100 3038.35 0.233333333 0.39 0.741081703 Up 0.227565911 Arpp21 "cyclic AMP-regulated phosphoprotein, 21" K02360|1|2e-32|144|ame:408476|a component of the cytoplasm (encore) GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0097159//organic cyclic compound binding;GO:0005515//protein binding;GO:0097159//organic cyclic compound binding;GO:0005515//protein binding;GO:0097159//organic cyclic compound binding;GO:0005515//protein binding;GO:0097159//organic cyclic compound binding;GO:0005515//protein binding;GO:0097159//organic cyclic compound binding;GO:0005515//protein binding;GO:0097159//organic cyclic compound binding;GO:0005515//protein binding;GO:0097159//organic cyclic compound binding;GO:0005515//protein binding;GO:0097159//organic cyclic compound binding;GO:0005515//protein binding GO:0009408//response to heat;GO:0009408//response to heat;GO:0009408//response to heat;GO:0009408//response to heat;GO:0009408//response to heat;GO:0009408//response to heat;GO:0009408//response to heat;GO:0009408//response to heat;GO:0009408//response to heat gi|26334933|dbj|BAC31167.1|/2.40533e-77/unnamed protein product [Mus musculus] 68789 1361.83 1.273333333 1.03 -0.3059658 Down 0.227500094 Trmt61b tRNA methyltransferase 61B K08694|1|6e-10|66.2|mmu:70891|speedy - - - - 240476 7909 1.03 1.273333333 0.3059658 Up 0.227500094 Zfp407 zinc finger protein 407 K09228|1|3e-71|274|bfo:BRAFLDRAFT_66688|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|256223449|ref|NP_001028513.2|/0/zinc finger protein 407 [Mus musculus] 240068 6383 0.383333333 0.56 0.546827372 Up 0.227434277 Zfp563 zinc finger protein 563 K09228|1|0.0|965|mmu:240068|KRAB domain-containing zinc finger protein GO:0016020//membrane - GO:0009408//response to heat;GO:0032496//response to lipopolysaccharide gi|113930758|ref|NP_001020121.2|/0/zinc finger protein 563 [Mus musculus] 15221 2373 0.376666667 0.553333333 0.554860469 Up 0.227434277 Foxd3 forkhead box D3 K09397|1|2e-111|406|mmu:15221|forkhead box protein D GO:0000785//chromatin "GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding" GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0043009//chordate embryonic development;GO:0030154//cell differentiation gi|90133397|sp|Q61060.3|FOXD3_MOUSE/1.41601e-110/RecName: Full=Forkhead box protein D3; AltName: Full=HNF3/FH transcription factor genesis; AltName: Full=Hepatocyte nuclear factor 3 forkhead homolog 2; Short=HFH-2 12193 3537 13.17666667 12.31333333 -0.097764089 Down 0.227377863 Zfp36l2 "zinc finger protein 36, C3H type-like 2" K18753|1|4e-152|541|mmu:12193|butyrate response factor 1 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0030217//T cell differentiation;GO:0006351//transcription, DNA-templated;GO:0043487//regulation of RNA stability" gi|74144555|dbj|BAE36112.1|/4.0086e-176/unnamed protein product [Mus musculus] 12181 2476 12.24333333 13.10666667 0.098304426 Up 0.227377863 Bop1 block of proliferation 1 K14824|1|0.0|1384|mmu:12181|ribosome biogenesis protein ERB1 GO:0031981//nuclear lumen;GO:0030686//90S preribosome GO:0005488//binding "GO:0007049//cell cycle;GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)" gi|37359780|dbj|BAC97868.1|/0/mKIAA0124 protein [Mus musculus] 110196 1281.96 12.14333333 13.00333333 0.098717003 Up 0.227377863 Fdps farnesyl diphosphate synthetase K00787|1|0.0|758|cge:100754883|farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] GO:0031981//nuclear lumen;GO:0042579//microbody;GO:0044429;GO:0042579//microbody;GO:0044429 GO:0043169//cation binding;GO:0004659//prenyltransferase activity;GO:0043169//cation binding;GO:0004659//prenyltransferase activity GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0070542//response to fatty acid;GO:0008406//gonad development;GO:0048545//response to steroid hormone;GO:0006695//cholesterol biosynthetic process;GO:0006720//isoprenoid metabolic process;GO:0036314;GO:0048232//male gamete generation;GO:0008654//phospholipid biosynthetic process;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0006695//cholesterol biosynthetic process;GO:0006720//isoprenoid metabolic process;GO:0008654//phospholipid biosynthetic process gi|359279938|ref|NP_001240680.1|/0/farnesyl pyrophosphate synthase isoform 1 precursor [Mus musculus] 74574 3219 0.473333333 0.306666667 -0.626185163 Down 0.227359058 Lvrn laeverin K13724|1|0.0|1894|mmu:74574|aminopeptidase Q [EC:3.4.11.-] - - - gi|254588010|ref|NP_083284.1|/0/aminopeptidase Q [Mus musculus] 217835 3830.65 20.71 19.48 -0.088333876 Down 0.227340253 Rin3 Ras and Rab interactor 3 K17638|1|8e-42|175|oaa:100093582|Ras and Rab interactor 1 - - - - 50772 4205 7.396666667 6.803333333 -0.120633485 Down 0.227302644 Mapk6 mitogen-activated protein kinase 6 K06855|1|0.0|1408|mmu:50772|mitogen-activated protein kinase 4/6 [EC:2.7.11.24] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0019900//kinase binding;GO:0046983//protein dimerization activity;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0019900//kinase binding;GO:0046983//protein dimerization activity;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction gi|537184579|gb|ERE76281.1|/0/mitogen-activated protein kinase 6 [Cricetulus griseus] 102162 2893 6.633333333 7.223333333 0.122930723 Up 0.227302644 Taf5l TATA-box binding protein associated factor 5 like K03130|1|0.0|1098|mmu:102162|transcription initiation factor TFIID subunit 5 GO:0070461//SAGA-type complex;GO:0005667//transcription factor complex - "GO:0006351//transcription, DNA-templated;GO:0016573//histone acetylation" gi|19527184|ref|NP_598727.1|/0/TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L [Mus musculus] 67579 7580 4.36 3.926666667 -0.151023002 Down 0.22724623 Cpeb4 cytoplasmic polyadenylation element binding protein 4 K02602|1|0.0|1234|rno:303010|cytoplasmic polyadenylation element-binding protein - - - - 12466 2303 41.57 43.90333333 0.078787732 Up 0.227218022 Cct6a "chaperonin containing Tcp1, subunit 6a (zeta)" K09498|1|0.0|977|mmu:12466|T-complex protein 1 subunit zeta GO:0030141//secretory granule;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton GO:0032550;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0035036//sperm-egg recognition gi|6753324|ref|NP_033968.1|/0/T-complex protein 1 subunit zeta [Mus musculus] 232821 1332 0.336666667 0.183333333 -0.876851769 Down 0.227189815 Ccdc106 coiled-coil domain containing 106 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - "gi|148699338|gb|EDL31285.1|/0/coiled-coil domain containing 106, isoform CRA_c, partial [Mus musculus]" 22209 1746 18.72666667 19.94333333 0.090812439 Up 0.227152206 Ube2a ubiquitin-conjugating enzyme E2A K10573|1|3e-96|355|ocu:100339096|ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] - - - - 70162 557 0.186666667 0.34 0.86507042 Up 0.227086389 Hk1os "hexokinase 1, opposite strand" - - - - - 19243 4153 41.28 38.97333333 -0.082955642 Down 0.227039377 Ptp4a1 protein tyrosine phosphatase 4a1 K18041|1|3e-97|360|ptg:102962583|protein tyrosine phosphatase type IVA [EC:3.1.3.48] GO:0015630//microtubule cytoskeleton;GO:0044459;GO:0005768//endosome GO:0004725//protein tyrosine phosphatase activity GO:0016477//cell migration;GO:0006470//protein dephosphorylation;GO:0032502//developmental process "gi|148682476|gb|EDL14423.1|/1.52519e-97/protein tyrosine phosphatase 4a1, isoform CRA_b, partial [Mus musculus]" 268515 10756 2.136666667 1.84 -0.21565609 Down 0.227029975 Bahcc1 BAH domain and coiled-coil containing 1 K00558|1|6e-06|58.2|bfo:BRAFLDRAFT_204680|DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] - - - gi|169658369|ref|NP_940815.3|/0/BAH and coiled-coil domain-containing protein 1 [Mus musculus] 75570 1415 2.253333333 2.58 0.19531032 Up 0.227029975 Nhej1 nonhomologous end-joining factor 1 K10980|1|6e-153|543|mmu:75570|non-homologous end-joining factor 1 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0009314//response to radiation;GO:0030098//lymphocyte differentiation;GO:0000726 gi|158517917|ref|NP_083618.3|/4.97621e-152/non-homologous end-joining factor 1 [Mus musculus] 17117 2575 13.28333333 12.43 -0.095790927 Down 0.226935951 Amacr alpha-methylacyl-CoA racemase K01796|1|0.0|701|mmu:17117|alpha-methylacyl-CoA racemase [EC:5.1.99.4] GO:0042579//microbody GO:0016854//racemase and epimerase activity;GO:0005515//protein binding GO:0006694//steroid biosynthetic process;GO:0032787//monocarboxylic acid metabolic process gi|46518506|ref|NP_032563.2|/0/alpha-methylacyl-CoA racemase [Mus musculus] 75565 1174 12.41333333 11.56 -0.102749174 Down 0.226935951 Sgf29 SAGA complex associated factor 29 K11364|1|2e-167|590|mmu:75565|SAGA-associated factor 29 GO:0000123//histone acetyltransferase complex GO:0042393//histone binding "GO:0070199//establishment of protein localization to chromosome;GO:0006351//transcription, DNA-templated;GO:0016573//histone acetylation" gi|228008310|ref|NP_083615.3|/2.06839e-166/SAGA-associated factor 29 [Mus musculus] 22631 3384.84 42.76 45.05333333 0.075371997 Up 0.226935951 Ywhaz "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide" K16197|1|2e-126|456|rno:25578|14-3-3 protein beta/theta/zeta GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0044327//dendritic spine head;GO:0048770;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0044327//dendritic spine head;GO:0048770;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0044327//dendritic spine head;GO:0048770;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0044327//dendritic spine head;GO:0048770 GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0007599//hemostasis;GO:0006605//protein targeting;GO:0006915//apoptotic process;GO:0016070//RNA metabolic process;GO:0002441;GO:0001775//cell activation;GO:0007599//hemostasis;GO:0006605//protein targeting;GO:0006915//apoptotic process;GO:0016070//RNA metabolic process;GO:0002441;GO:0001775//cell activation;GO:0007599//hemostasis;GO:0006605//protein targeting;GO:0006915//apoptotic process;GO:0016070//RNA metabolic process;GO:0002441;GO:0001775//cell activation;GO:0007599//hemostasis;GO:0006605//protein targeting;GO:0006915//apoptotic process;GO:0016070//RNA metabolic process;GO:0002441;GO:0001775//cell activation "gi|148676868|gb|EDL08815.1|/1.63054e-132/tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, isoform CRA_b, partial [Mus musculus]" 69882 2908.41 8.623333333 9.313333333 0.111051967 Up 0.226841927 Vwa9 von Willebrand factor A domain containing 9 - GO:0044424;GO:0044424 - - gi|117647251|ref|NP_780362.2|/0/von Willebrand factor A domain-containing protein 9 [Mus musculus] 68421 5367.9 9.033333333 8.343333333 -0.114634561 Down 0.226841927 Lmbrd1 LMBR1 domain containing 1 K14617|1|0.0|889|mmu:68421|LMBR1 domain-containing protein 1 - - - - 433365 2527 3.11 3.493333333 0.167689731 Up 0.226832525 Teddm1b transmembrane epididymal protein 1B - GO:0016020//membrane - - gi|56606033|ref|NP_001008426.1|/1.55597e-155/uncharacterized protein LOC433365 [Mus musculus] 54486 3298 0.32 0.493333333 0.624490865 Up 0.226804318 Hpgds hematopoietic prostaglandin D synthase K04097|1|7e-113|411|mmu:54486|prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18] GO:0031981//nuclear lumen "GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0016860//intramolecular oxidoreductase activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups" GO:0006693//prostaglandin metabolic process gi|254281300|ref|NP_062328.3|/6.45292e-112/hematopoietic prostaglandin D synthase [Mus musculus] 100463519 1424 0.583333333 0.786666667 0.431431938 Up 0.226794915 BB283400 expressed sequence BB283400 - - - - "gi|67975423|ref|XP_668908.1|/1.39121e-14/hypothetical protein [Plasmodium berghei strain ANKA], partial [Plasmodium berghei ANKA]" 432396 554 0.563333333 0.76 0.432010578 Up 0.226794915 Zfp652os "zinc finger protein 652, opposite strand" - - - - - 216188 6030 0.663333333 0.87 0.391281376 Up 0.226785513 Aldh1l2 "aldehyde dehydrogenase 1 family, member L2" K00289|1|0.0|1824|mmu:216188|formyltetrahydrofolate dehydrogenase [EC:1.5.1.6] GO:0043231//intracellular membrane-bounded organelle "GO:0016741;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0016903//oxidoreductase activity, acting on the aldehyde or oxo group of donors" GO:0009256//10-formyltetrahydrofolate metabolic process gi|283436218|ref|NP_705771.2|/0/mitochondrial 10-formyltetrahydrofolate dehydrogenase [Mus musculus] 15273 9788 1.94 1.65 -0.233590628 Down 0.226766708 Hivep2 human immunodeficiency virus type I enhancer binding protein 2 K09239|1|0.0|4360|mmu:15273|human immunodeficiency virus type I enhancer-binding protein GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated;GO:0007154//cell communication" gi|85861241|ref|NP_034567.2|/0/transcription factor HIVEP2 [Mus musculus] 218194 4749.44 1.683333333 1.976666667 0.231748717 Up 0.226766708 Phactr1 phosphatase and actin regulator 1 K17594|1|1e-74|285|aam:106492795|phosphatase and actin regulator 3 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0008092//cytoskeletal protein binding;GO:0019903//protein phosphatase binding;GO:0019212//phosphatase inhibitor activity;GO:0008092//cytoskeletal protein binding;GO:0019903//protein phosphatase binding GO:0044092//negative regulation of molecular function;GO:0051017//actin filament bundle assembly;GO:0006928//movement of cell or subcellular component;GO:0016310//phosphorylation;GO:0051017//actin filament bundle assembly;GO:0065007//biological regulation;GO:0006928//movement of cell or subcellular component;GO:0016310//phosphorylation "gi|148709038|gb|EDL40984.1|/0/phosphatase and actin regulator 1, isoform CRA_a, partial [Mus musculus]" 225362 1920 0.406666667 0.59 0.536868213 Up 0.226757306 Reep2 receptor accessory protein 2 K17338|1|1e-129|466|mmu:225362|receptor expression-enhancing protein 1/2/3/4 GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0001664//G-protein coupled receptor binding;GO:0001664//G-protein coupled receptor binding GO:0032594//protein transport within lipid bilayer;GO:0050909//sensory perception of taste;GO:0032594//protein transport within lipid bilayer;GO:0050909//sensory perception of taste gi|54261730|ref|NP_659114.2|/1.16081e-128/receptor expression-enhancing protein 2 isoform 1 [Mus musculus] 77053 3908.22 19.15 17.94666667 -0.093628483 Down 0.226588063 Sun1 Sad1 and UNC84 domain containing 1 K19347|1|0.0|1678|mmu:77053|SUN domain-containing protein 1/2 GO:0031229;GO:0031981//nuclear lumen;GO:0001669//acrosomal vesicle;GO:0034992//microtubule organizing center attachment site;GO:0031229;GO:0031981//nuclear lumen;GO:0001669//acrosomal vesicle;GO:0034992//microtubule organizing center attachment site;GO:0031229;GO:0031981//nuclear lumen;GO:0001669//acrosomal vesicle;GO:0034992//microtubule organizing center attachment site;GO:0031229;GO:0031981//nuclear lumen;GO:0001669//acrosomal vesicle;GO:0034992//microtubule organizing center attachment site;GO:0031229;GO:0031981//nuclear lumen;GO:0001669//acrosomal vesicle;GO:0034992//microtubule organizing center attachment site GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0007010//cytoskeleton organization;GO:0043578//nuclear matrix organization;GO:0007010//cytoskeleton organization;GO:0043578//nuclear matrix organization;GO:0007010//cytoskeleton organization;GO:0043578//nuclear matrix organization;GO:0007010//cytoskeleton organization;GO:0043578//nuclear matrix organization;GO:0007010//cytoskeleton organization;GO:0043578//nuclear matrix organization gi|568938851|ref|XP_006504830.1|/0/PREDICTED: SUN domain-containing protein 1 isoform X10 [Mus musculus] 21425 2356.69 19.51333333 20.71666667 0.086331646 Up 0.226588063 Tfeb transcription factor EB K15590|1|0.0|653|mmu:21425|transcription factor EB GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity GO:0006955//immune response;GO:0007033//vacuole organization;GO:0001701//in utero embryonic development;GO:0006914//autophagy;GO:0006366//transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0007033//vacuole organization;GO:0001701//in utero embryonic development;GO:0006914//autophagy;GO:0006366//transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0007033//vacuole organization;GO:0001701//in utero embryonic development;GO:0006914//autophagy;GO:0006366//transcription from RNA polymerase II promoter "gi|148691638|gb|EDL23585.1|/0/transcription factor EB, isoform CRA_c, partial [Mus musculus]" 12364 2605 1.58 1.323333333 -0.255748052 Down 0.226512844 Casp12 caspase 12 K04741|1|0.0|854|mmu:12364|caspase 12 [EC:3.4.22.-] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0004175//endopeptidase activity GO:0012502//induction of programmed cell death;GO:0097305//response to alcohol;GO:0034976//response to endoplasmic reticulum stress;GO:0009719;GO:0010039//response to iron ion;GO:0044767//single-organism developmental process;GO:0014070//response to organic cyclic compound;GO:0016485//protein processing;GO:0006984//ER-nucleus signaling pathway gi|157951684|ref|NP_033938.3|/0/caspase-12 [Mus musculus] 17155 3889 6.03 5.52 -0.127489735 Down 0.226512844 Man1a "mannosidase 1, alpha" "K01230|1|0.0|1266|mmu:17155|mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0015924//mannosyl-oligosaccharide mannosidase activity - "gi|568965058|ref|XP_006512631.1|/0/PREDICTED: mannosyl-oligosaccharide 1,2-alpha-mannosidase IA isoform X2 [Mus musculus]" 67486 3060 1.326666667 1.586666667 0.258193143 Up 0.226512844 Polr3g polymerase (RNA) III (DNA directed) polypeptide G K03024|1|6e-58|228|mmu:67486|DNA-directed RNA polymerase III subunit RPC7 - - GO:0032481//positive regulation of type I interferon production;GO:0002376//immune system process;GO:0031349//positive regulation of defense response gi|124487177|ref|NP_001074645.1|/5.43657e-57/DNA-directed RNA polymerase III subunit RPC7 [Mus musculus] 233744 6166 5.886666667 5.38 -0.129844764 Down 0.226512844 Spon1 "spondin 1, (f-spondin) extracellular matrix protein" K17341|1|2e-34|151|acs:100555616|hemicentin;K04596|2|5e-33|147|xma:102221541|brain-specific angiogenesis inhibitor 1 GO:0031012//extracellular matrix;GO:0044421 - GO:0022610 gi|21704174|ref|NP_663559.1|/0/spondin-1 precursor [Mus musculus] 17765 4226.31 1.326666667 1.59 0.261220835 Up 0.226512844 Mtf2 metal response element binding transcription factor 2 K11485|1|0.0|1140|mmu:17765|polycomb-like protein 2 GO:0031519//PcG protein complex;GO:0031519//PcG protein complex;GO:0031519//PcG protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0031519//PcG protein complex GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0003676//nucleic acid binding;GO:0042393//histone binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0003676//nucleic acid binding GO:0006366//transcription from RNA polymerase II promoter;GO:0031062//positive regulation of histone methylation;GO:0007389//pattern specification process;GO:0030154//cell differentiation;GO:0031061//negative regulation of histone methylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031062//positive regulation of histone methylation;GO:0007389//pattern specification process;GO:0030154//cell differentiation;GO:0031061//negative regulation of histone methylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031062//positive regulation of histone methylation;GO:0007389//pattern specification process;GO:0030154//cell differentiation;GO:0031061//negative regulation of histone methylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031062//positive regulation of histone methylation;GO:0007389//pattern specification process;GO:0030154//cell differentiation;GO:0031061//negative regulation of histone methylation gi|568935358|ref|XP_006534871.1|/0/PREDICTED: metal-response element-binding transcription factor 2 isoform X2 [Mus musculus] 331046 2767 2.996666667 2.636666667 -0.184643421 Down 0.226475234 Tgm4 transglutaminase 4 (prostate) K05621|1|0.0|1349|mmu:331046|transglutaminase 4 [EC:2.3.2.13] GO:0031224//intrinsic component of membrane "GO:0043169//cation binding;GO:0016755//transferase activity, transferring amino-acyl groups" GO:0006464//cellular protein modification process;GO:0007320//insemination gi|227500026|ref|NP_808579.2|/0/protein-glutamine gamma-glutamyltransferase 4 [Mus musculus] 17242 897.27 2.803333333 3.166666667 0.175821713 Up 0.226475234 Mdk midkine K06828|1|3e-54|213|cge:100752798|midkine - GO:0005102//receptor binding;GO:0005539//glycosaminoglycan binding;GO:0005102//receptor binding;GO:0005539//glycosaminoglycan binding;GO:0005102//receptor binding;GO:0005539//glycosaminoglycan binding;GO:0005102//receptor binding;GO:0005539//glycosaminoglycan binding;GO:0005102//receptor binding;GO:0005102//receptor binding;GO:0005539//glycosaminoglycan binding "GO:0035270//endocrine system development;GO:0048869//cellular developmental process;GO:0007613//memory;GO:0048870//cell motility;GO:0021695//cerebellar cortex development;GO:0048522;GO:0007588//excretion;GO:0031960//response to corticosteroid;GO:0021766//hippocampus development;GO:0006351//transcription, DNA-templated;GO:0002209//behavioral defense response;GO:0035270//endocrine system development;GO:0048869//cellular developmental process;GO:0007613//memory;GO:0048870//cell motility;GO:0021695//cerebellar cortex development;GO:0048522;GO:0007588//excretion;GO:0031960//response to corticosteroid;GO:0021766//hippocampus development;GO:0006351//transcription, DNA-templated;GO:0002209//behavioral defense response;GO:0035270//endocrine system development;GO:0048869//cellular developmental process;GO:0007613//memory;GO:0048870//cell motility;GO:0021695//cerebellar cortex development;GO:0048522;GO:0007588//excretion;GO:0031960//response to corticosteroid;GO:0021766//hippocampus development;GO:0006351//transcription, DNA-templated;GO:0002209//behavioral defense response;GO:0035270//endocrine system development;GO:0048869//cellular developmental process;GO:0007613//memory;GO:0048870//cell motility;GO:0021695//cerebellar cortex development;GO:0048522;GO:0007588//excretion;GO:0031960//response to corticosteroid;GO:0021766//hippocampus development;GO:0006351//transcription, DNA-templated;GO:0002209//behavioral defense response;GO:0035270//endocrine system development;GO:0050789;GO:0021543//pallium development;GO:0007613//memory;GO:0048870//cell motility;GO:0021695//cerebellar cortex development;GO:0007588//excretion;GO:0031960//response to corticosteroid;GO:0006351//transcription, DNA-templated;GO:0006950//response to stress;GO:0035270//endocrine system development;GO:0048869//cellular developmental process;GO:0007613//memory;GO:0048870//cell motility;GO:0021695//cerebellar cortex development;GO:0048522;GO:0007588//excretion;GO:0031960//response to corticosteroid;GO:0021766//hippocampus development;GO:0006351//transcription, DNA-templated;GO:0002209//behavioral defense response" gi|742134602|ref|XP_010840643.1|/4.15713e-53/PREDICTED: midkine isoform X1 [Bison bison bison] 14272 1881 36.98333333 39.18666667 0.083487597 Up 0.226437625 Fnta "farnesyltransferase, CAAX box, alpha" K05955|1|0.0|654|mmu:14272|protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha [EC:2.5.1.58 2.5.1.59] GO:0015630//microtubule cytoskeleton;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0033218//amide binding;GO:0008289//lipid binding;GO:0015631//tubulin binding;GO:0004661//protein geranylgeranyltransferase activity;GO:0030545 GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010558;GO:0010033//response to organic substance;GO:0018342//protein prenylation;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0022411;GO:0051345//positive regulation of hydrolase activity;GO:0051726//regulation of cell cycle;GO:0009966//regulation of signal transduction;GO:0007268//chemical synaptic transmission;GO:0090043//regulation of tubulin deacetylation gi|6679821|ref|NP_032059.1|/0/protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha [Mus musculus] 235661 2046 40.34 38.14333333 -0.080780158 Down 0.226437625 Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 "K10416|1|0.0|874|mmu:235661|dynein light intermediate chain 1, cytosolic" GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0000776//kinetochore;GO:0005819//spindle;GO:0030286//dynein complex GO:0032550;GO:0003774//motor activity GO:0051234//establishment of localization;GO:0007098//centrosome cycle;GO:0006928//movement of cell or subcellular component;GO:0000087//mitotic M phase;GO:0090232//positive regulation of spindle checkpoint gi|22122795|ref|NP_666341.1|/0/cytoplasmic dynein 1 light intermediate chain 1 [Mus musculus] 207740 1402 38.32333333 40.52 0.080411123 Up 0.226437625 Ubald1 UBA-like domain containing 1 - - - - "gi|148664838|gb|EDK97254.1|/1.3014e-120/mCG128738, isoform CRA_b [Mus musculus]" 100503157 633 0.486666667 0.676666667 0.475511358 Up 0.226437625 Gm15471 predicted gene 15471 K15341|1|9e-24|112|mmu:140917|DNA cross-link repair 1B protein [EC:3.1.-.-] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0044427 GO:0005488//binding;GO:0004527//exonuclease activity GO:0016233//telomere capping;GO:0022402//cell cycle process;GO:0033554//cellular response to stress "gi|148675643|gb|EDL07590.1|/1.44594e-25/mCG145912, partial [Mus musculus]" 72338 2981 0.47 0.656666667 0.482500467 Up 0.226437625 Wdr89 WD repeat domain 89 K02943|1|2e-27|127|hgl:101702556|large subunit ribosomal protein LP2 - - - "gi|148704537|gb|EDL36484.1|/0/mCG144956, partial [Mus musculus]" 21781 2546.6 12.45666667 11.61666667 -0.100721908 Down 0.226428222 Tfdp1 transcription factor Dp 1 K04683|1|2e-169|598|mmu:21781|transcription factor Dp-1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding "GO:0012501//programmed cell death;GO:0009888//tissue development;GO:0006351//transcription, DNA-templated;GO:0051052//regulation of DNA metabolic process;GO:0012501//programmed cell death;GO:0009888//tissue development;GO:0006351//transcription, DNA-templated;GO:0051052//regulation of DNA metabolic process;GO:0012501//programmed cell death;GO:0009888//tissue development;GO:0006351//transcription, DNA-templated;GO:0051052//regulation of DNA metabolic process;GO:0012501//programmed cell death;GO:0009888//tissue development;GO:0006351//transcription, DNA-templated;GO:0051052//regulation of DNA metabolic process" gi|6678305|ref|NP_033387.1|/1.59808e-168/transcription factor Dp-1 isoform a [Mus musculus] 97287 2676 12.11 12.95 0.096753233 Up 0.226428222 Mtmr14 myotubularin related protein 14 K18086|1|0.0|1263|mmu:97287|myotubularin-related protein 14 [EC:3.1.3.64 3.1.3.95] GO:0044444//cytoplasmic part GO:0004721//phosphoprotein phosphatase activity;GO:0052744//phosphatidylinositol monophosphate phosphatase activity GO:0006796//phosphate-containing compound metabolic process gi|163937863|ref|NP_081125.2|/0/myotubularin-related protein 14 [Mus musculus] 107071 1220 12.99333333 12.15 -0.096815276 Down 0.226428222 Wdr74 WD repeat domain 74 K14841|1|0.0|748|mmu:107071|ribosome biogenesis protein NSA1 GO:0031981//nuclear lumen - GO:0044260;GO:0001824//blastocyst development gi|19527374|ref|NP_598900.1|/0/WD repeat-containing protein 74 [Mus musculus] 53414 3854 18.4 19.59333333 0.090657092 Up 0.226409417 Bysl bystin-like K14797|1|0.0|793|mmu:53414|essential nuclear protein 1 GO:0005874//microtubule;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part - GO:0007417//central nervous system development;GO:0001825//blastocyst formation;GO:0022613//ribonucleoprotein complex biogenesis;GO:0070848//response to growth factor;GO:0014070//response to organic cyclic compound;GO:0030154//cell differentiation;GO:0070555//response to interleukin-1;GO:0032496//response to lipopolysaccharide gi|164698440|ref|NP_058555.3|/0/bystin [Mus musculus] 622139 712 1.823333333 1.543333333 -0.24052864 Down 0.22638121 Clca4c-ps "chloride channel accessory 4C, pseudogene" K05030|1|1e-68|261|mmu:99663|calcium-activated chloride channel regulator 4 GO:0031224//intrinsic component of membrane GO:0005253//anion channel activity GO:0015698//inorganic anion transport gi|74226370|dbj|BAE23897.1|/1.03811e-79/unnamed protein product [Mus musculus] 320100 2817 1.543333333 1.826666667 0.2431637 Up 0.22638121 Relt RELT tumor necrosis factor receptor K05156|1|0.0|739|mmu:320100|tumor necrosis factor receptor superfamily member 19-like GO:0044424;GO:0031224//intrinsic component of membrane - GO:0008219//cell death gi|568950832|ref|XP_006507993.1|/0/PREDICTED: tumor necrosis factor receptor superfamily member 19L isoform X2 [Mus musculus] 433424 1272.46 1.843333333 1.56 -0.240770951 Down 0.22638121 Zeb2os "zinc finger E-box binding homeobox 2, opposite strand" - - - - "gi|148694918|gb|EDL26865.1|/1.10317e-32/mCG124345, isoform CRA_a [Mus musculus]" 58235 5079 1.83 1.55 -0.239575433 Down 0.22638121 Pvrl1 nectin cell adhesion molecule 1 K06081|1|0.0|931|mmu:58235|poliovirus receptor-related protein 1 GO:0005911//cell-cell junction;GO:0030426//growth cone;GO:0043227//membrane-bounded organelle;GO:0019897//extrinsic component of plasma membrane;GO:0031224//intrinsic component of membrane GO:0046983//protein dimerization activity;GO:0042802//identical protein binding GO:0034505//tooth mineralization;GO:0016337//single organismal cell-cell adhesion;GO:0002088//lens development in camera-type eye;GO:0019048//modulation by virus of host morphology or physiology;GO:0006935//chemotaxis;GO:0000041//transition metal ion transport;GO:0007416//synapse assembly;GO:0045216//cell-cell junction organization "gi|148693608|gb|EDL25555.1|/0/poliovirus receptor-related 1, isoform CRA_a, partial [Mus musculus]" 27041 2685 37.43 39.61666667 0.081912449 Up 0.226371808 G3bp1 GTPase activating protein (SH3 domain) binding protein 1 K17265|1|0.0|690|mmu:27041|Ras GTPase-activating protein-binding protein 1 [EC:3.6.4.12 3.6.4.13] GO:0035770//ribonucleoprotein granule;GO:0016020//membrane GO:0003723//RNA binding;GO:0004518//nuclease activity GO:0030178//negative regulation of Wnt signaling pathway gi|60359872|dbj|BAD90155.1|/0/mKIAA4115 protein [Mus musculus] 626391 2903 0.5 0.326666667 -0.614108846 Down 0.226343601 Zfp951 zinc finger protein 951 K09228|1|0.0|1009|mmu:626391|KRAB domain-containing zinc finger protein - - - gi|162287421|ref|NP_001034320.3|/0/kruppel-related zinc finger protein-like [Mus musculus] 102633315 935 0.33 0.503333333 0.609048119 Up 0.226343601 Gm16159 predicted gene 16159 K04362|1|2e-10|68.9|lve:103069902|fibroblast growth factor receptor 1 [EC:2.7.10.1] - - - - 74694 5713 0.5 0.326666667 -0.614108846 Down 0.226343601 Tbc1d30 "TBC1 domain family, member 30" K19953|1|1e-27|129|soc:105200287|TBC1 domain family member 6 GO:0044464;GO:0016020//membrane - - gi|50510743|dbj|BAD32357.1|/0/mKIAA0984 protein [Mus musculus] 100689703 2836 0.776666667 0.993333333 0.354982376 Up 0.226324796 9330133O14Rik RIKEN cDNA 9330133O14 gene - - - - "gi|148679736|gb|EDL11683.1|/2.72973e-63/mCG1036165, isoform CRA_b, partial [Mus musculus]" 76983 2192 7.076666667 6.496666667 -0.123370281 Down 0.226315394 Scfd1 Sec1 family domain containing 1 K19998|1|0.0|1235|mmu:76983|sec1 family domain-containing protein 1 "GO:0043234//protein complex;GO:0000139//Golgi membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0043234//protein complex;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0016020//membrane" GO:0000149//SNARE binding;GO:0000149//SNARE binding GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0042221//response to chemical;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0006888//ER to Golgi vesicle-mediated transport gi|58037481|ref|NP_084101.1|/0/sec1 family domain-containing protein 1 isoform 1 [Mus musculus] 17125 3133 6.896666667 7.476666667 0.116495975 Up 0.226315394 Smad1 SMAD family member 1 K04676|1|0.0|782|mmu:17125|mothers against decapentaplegic homolog 1 GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0019866//organelle inner membrane;GO:0044444//cytoplasmic part "GO:0001071//nucleic acid binding transcription factor activity;GO:0019900//kinase binding;GO:0043169//cation binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0005072//transforming growth factor beta receptor, cytoplasmic mediator activity" GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0035295//tube development;GO:0001501//skeletal system development;GO:0007420//brain development;GO:0006952//defense response;GO:0051094//positive regulation of developmental process;GO:0048333//mesodermal cell differentiation;GO:0031346//positive regulation of cell projection organization;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001649//osteoblast differentiation;GO:0019953//sexual reproduction;GO:0065008//regulation of biological quality;GO:0006464//cellular protein modification process;GO:0071363//cellular response to growth factor stimulus;GO:0014855;GO:0009611//response to wounding;GO:0009719 gi|31543220|ref|NP_032565.2|/0/mothers against decapentaplegic homolog 1 [Mus musculus] 24086 4967.13 7.073333333 6.49 -0.124171772 Down 0.226315394 Tlk2 tousled-like kinase 2 (Arabidopsis) K08864|1|0.0|1202|cge:100771294|tousled-like kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043232;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043232;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043232;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity GO:0010332//response to gamma radiation;GO:0006333//chromatin assembly or disassembly;GO:0031330;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0033554//cellular response to stress;GO:0010332//response to gamma radiation;GO:0006333//chromatin assembly or disassembly;GO:0031330;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0033554//cellular response to stress;GO:0010332//response to gamma radiation;GO:0006333//chromatin assembly or disassembly;GO:0031330;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0033554//cellular response to stress;GO:0010332//response to gamma radiation;GO:0006333//chromatin assembly or disassembly;GO:0031330;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0033554//cellular response to stress;GO:0010332//response to gamma radiation;GO:0006333//chromatin assembly or disassembly;GO:0031330;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0033554//cellular response to stress "gi|42490892|gb|AAH66198.1|/0/Tlk2 protein, partial [Mus musculus]" 77113 3319 7.306666667 6.723333333 -0.120036714 Down 0.226315394 Klhl2 "kelch-like 2, Mayven" K10443|1|0.0|1159|mmu:77113|kelch-like protein 2/3 GO:0005856//cytoskeleton;GO:0031461//cullin-RING ubiquitin ligase complex GO:0042802//identical protein binding;GO:0008092//cytoskeletal protein binding GO:0032446//protein modification by small protein conjugation gi|110347553|ref|NP_848748.2|/0/kelch-like protein 2 [Mus musculus] 67525 3216 1.383333333 1.65 0.254317189 Up 0.226258979 Trim62 tripartite motif-containing 62 K12030|1|0.0|951|mcf:102140967|tripartite motif-containing protein 62 [EC:2.3.2.27] GO:0044464 GO:0046914//transition metal ion binding - gi|694884802|ref|XP_009451488.1|/0/PREDICTED: E3 ubiquitin-protein ligase TRIM62 [Pan troglodytes] 271377 4999 1.74 1.466666667 -0.246546283 Down 0.226258979 Zbtb11 zinc finger and BTB domain containing 11 K10498|1|0.0|1909|mmu:271377|zinc finger and BTB domain-containing protein 11 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding - gi|258645088|ref|NP_766614.2|/0/zinc finger and BTB domain-containing protein 11 [Mus musculus] 59052 1850 36.50666667 38.69 0.083800783 Up 0.226249577 Mettl9 methyltransferase like 9 - - GO:0005488//binding - gi|34328259|ref|NP_067529.2|/1.80398e-171/methyltransferase-like protein 9 precursor [Mus musculus] 100504661 1142 2.803333333 2.463333333 -0.186531436 Down 0.226249577 Gm20337 "predicted gene, 20337" - - - - - 18858 1855.36 38.96666667 36.78666667 -0.083057568 Down 0.226249577 Pmp22 peripheral myelin protein 22 K19289|1|4e-71|271|mmu:18858|peripheral myelin protein 22 GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0043209//myelin sheath;GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0043209//myelin sheath;GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0043209//myelin sheath;GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0043209//myelin sheath;GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0043209//myelin sheath;GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0043209//myelin sheath;GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0043209//myelin sheath - GO:0008366//axon ensheathment;GO:0022402//cell cycle process;GO:0010927;GO:0010975//regulation of neuron projection development;GO:0008283//cell proliferation;GO:0008366//axon ensheathment;GO:0022402//cell cycle process;GO:0010927;GO:0010975//regulation of neuron projection development;GO:0008283//cell proliferation;GO:0008366//axon ensheathment;GO:0022402//cell cycle process;GO:0010927;GO:0010975//regulation of neuron projection development;GO:0008283//cell proliferation;GO:0008366//axon ensheathment;GO:0022402//cell cycle process;GO:0010927;GO:0010975//regulation of neuron projection development;GO:0008283//cell proliferation;GO:0008366//axon ensheathment;GO:0022402//cell cycle process;GO:0010927;GO:0010975//regulation of neuron projection development;GO:0008283//cell proliferation;GO:0008366//axon ensheathment;GO:0022402//cell cycle process;GO:0010927;GO:0010975//regulation of neuron projection development;GO:0008283//cell proliferation;GO:0008366//axon ensheathment;GO:0022402//cell cycle process;GO:0010927;GO:0010975//regulation of neuron projection development;GO:0008283//cell proliferation gi|130338|sp|P16646.2|PMP22_MOUSE/3.03181e-70/RecName: Full=Peripheral myelin protein 22; Short=PMP-22; AltName: Full=Growth arrest-specific protein 3; Short=GAS-3 98256 2512 0.24 0.106666667 -1.169925001 Down 0.226230772 Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) K00486|1|0.0|957|mmu:98256|kynurenine 3-monooxygenase [EC:1.14.13.9] GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane;GO:0019866//organelle inner membrane "GO:0000166//nucleotide binding;GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen" GO:0006575//cellular modified amino acid metabolic process;GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0006970//response to osmotic stress;GO:0006569//tryptophan catabolic process "gi|148681262|gb|EDL13209.1|/0/kynurenine 3-monooxygenase (kynurenine 3-hydroxylase), partial [Mus musculus]" 231997 2714 4.66 5.12 0.135813855 Up 0.226202565 Fkbp14 FK506 binding protein 14 K09577|1|5e-112|408|mmu:231997|FK506-binding protein 14 [EC:5.2.1.8] - - - gi|23956366|ref|NP_705801.1|/4.35446e-111/peptidyl-prolyl cis-trans isomerase FKBP14 precursor [Mus musculus] 74427 4238 5.09 4.626666667 -0.137692494 Down 0.226202565 Eaf1 ELL associated factor 1 K15186|1|4e-137|492|cge:100754458|ELL-associated factor - - - "gi|148692866|gb|EDL24813.1|/1.34878e-141/ELL associated factor 1, partial [Mus musculus]" 210973 3868 4.54 4.996666667 0.13827368 Up 0.226202565 Kbtbd2 kelch repeat and BTB (POZ) domain containing 2 K10470|1|0.0|1205|mmu:210973|kelch repeat and BTB domain-containing protein 2 - - - gi|37360412|dbj|BAC98184.1|/0/mKIAA1489 protein [Mus musculus] 245386 2065.53 0.91 1.136666667 0.320870788 Up 0.226164955 Tmem255a transmembrane protein 255A K00909|1|8e-49|197|tru:101076509|rhodopsin kinase [EC:2.7.11.14] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148697062|gb|EDL29009.1|/3.50983e-169/RIKEN cDNA 6430550H21, isoform CRA_a, partial [Mus musculus]" 21944 1694 18.03666667 19.21333333 0.091175094 Up 0.226164955 Tnfsf12 "tumor necrosis factor (ligand) superfamily, member 12" K05474|1|4e-91|338|mmu:21944|tumor necrosis factor ligand superfamily member 12 GO:0016021//integral component of membrane;GO:0044444//cytoplasmic part;GO:0044421 GO:0005102//receptor binding GO:0016477//cell migration;GO:0012502//induction of programmed cell death;GO:0001525//angiogenesis;GO:0097191//extrinsic apoptotic signaling pathway;GO:0001935//endothelial cell proliferation "gi|74221419|dbj|BAE42185.1|/3.0951e-90/unnamed protein product, partial [Mus musculus]" 65115 3191 0.91 1.136666667 0.320870788 Up 0.226164955 Bean1 "brain expressed, associated with Nedd4, 1" K19324|1|1e-98|363|mmu:65115|protein BEAN1 - - - gi|213512434|ref|NP_001135394.1|/1.9876e-126/protein BEAN1 isoform a [Mus musculus] 72739 2602.21 8.986666667 9.666666667 0.105232404 Up 0.226089736 Zkscan3 zinc finger with KRAB and SCAN domains 3 K09229|1|0.0|1107|mmu:72739|KRAB and SCAN domains-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0044764;GO:0048585;GO:0007033//vacuole organization;GO:0006351//transcription, DNA-templated;GO:0006914//autophagy;GO:0044764;GO:0048585;GO:0007033//vacuole organization;GO:0006351//transcription, DNA-templated;GO:0006914//autophagy" gi|224809350|ref|NP_076174.3|/0/zinc finger protein with KRAB and SCAN domains 3 [Mus musculus] 67229 3431 8.8 9.483333333 0.107890723 Up 0.226089736 Prpf18 pre-mRNA processing factor 18 K12817|1|0.0|681|mmu:67229|pre-mRNA-splicing factor 18 - - - - 69834 4328.9 9.006666667 8.33 -0.112676773 Down 0.226089736 Rab43 "RAB43, member RAS oncogene family" K07930|1|1e-73|281|mmu:69834|Ras-related protein Rab-43 GO:0030666//endocytic vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0030666//endocytic vesicle membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0006996//organelle organization;GO:0016192//vesicle-mediated transport;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction;GO:0006996//organelle organization;GO:0016192//vesicle-mediated transport;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction;GO:0006996//organelle organization;GO:0016192//vesicle-mediated transport;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction;GO:0006996//organelle organization;GO:0016192//vesicle-mediated transport;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction gi|86476069|ref|NP_001034483.1|/2.45311e-112/ras-related protein Rab-43 isoform a [Mus musculus] 16337 9357 9.686666667 9.006666667 -0.105007028 Down 0.226089736 Insr insulin receptor K04527|1|0.0|2726|mmu:16337|insulin receptor [EC:2.7.10.1] GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0044444//cytoplasmic part GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0017046//peptide hormone binding;GO:0019902//phosphatase binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0005504//fatty acid binding;GO:0019901//protein kinase binding;GO:0005520//insulin-like growth factor binding "GO:0031016//pancreas development;GO:0032409;GO:0032868//response to insulin;GO:0005978//glycogen biosynthetic process;GO:0006809//nitric oxide biosynthetic process;GO:0010828//positive regulation of glucose transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0032147//activation of protein kinase activity;GO:0009790//embryo development;GO:0006096//glycolytic process;GO:0006351//transcription, DNA-templated;GO:0031960//response to corticosteroid;GO:0016477//cell migration;GO:0009101//glycoprotein biosynthetic process;GO:0045927//positive regulation of growth;GO:0019048//modulation by virus of host morphology or physiology;GO:0042743//hydrogen peroxide metabolic process;GO:0070848//response to growth factor;GO:0051262//protein tetramerization;GO:0033500//carbohydrate homeostasis;GO:0043627//response to estrogen;GO:0006260//DNA replication;GO:0030154//cell differentiation;GO:0009991//response to extracellular stimulus;GO:0010038//response to metal ion;GO:0008283//cell proliferation;GO:0009746;GO:0034097//response to cytokine;GO:0000165//MAPK cascade;GO:0097305//response to alcohol;GO:0007067//mitotic nuclear division;GO:0009887//organ morphogenesis" gi|157057178|ref|NP_034698.2|/0/insulin receptor precursor [Mus musculus] 13654 2972 0.393333333 0.236666667 -0.73289593 Down 0.226070932 Egr2 early growth response 2 K12496|1|0.0|713|mmu:13654|early growth response protein 2 GO:0043231//intracellular membrane-bounded organelle GO:0044389//ubiquitin-like protein ligase binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0000975//regulatory region DNA binding GO:0007411//axon guidance;GO:0006366//transcription from RNA polymerase II promoter;GO:0021594//rhombomere formation;GO:0048167//regulation of synaptic plasticity;GO:0001503//ossification;GO:0006886//intracellular protein transport;GO:0021604;GO:0043434//response to peptide hormone;GO:0007422//peripheral nervous system development;GO:0007519//skeletal muscle tissue development;GO:0008366//axon ensheathment;GO:0044708//single-organism behavior gi|183583542|ref|NP_034248.2|/0/E3 SUMO-protein ligase EGR2 [Mus musculus] 320360 5281 0.243333333 0.4 0.717066037 Up 0.226070932 Ric3 RIC3 acetylcholine receptor chaperone - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0006461//protein complex assembly;GO:0006461//protein complex assembly;GO:0006461//protein complex assembly gi|84490396|ref|NP_001033713.1|/4.35863e-153/protein RIC-3 isoform a precursor [Mus musculus] 56698 1847.89 11.74 12.57333333 0.098934767 Up 0.226005115 Phax phosphorylated adaptor for RNA export K14291|1|0.0|684|mmu:56698|phosphorylated adapter RNA export protein GO:0016604//nuclear body;GO:0044297//cell body;GO:0016604//nuclear body;GO:0044297//cell body GO:0005488//binding;GO:0005488//binding GO:0006405//RNA export from nucleus;GO:0045184//establishment of protein localization;GO:0006405//RNA export from nucleus;GO:0045184//establishment of protein localization gi|253314461|ref|NP_001156461.1|/0/phosphorylated adapter RNA export protein isoform 2 [Mus musculus] 74007 5808 0.593333333 0.793333333 0.419084332 Up 0.225958103 Btbd11 BTB (POZ) domain containing 11 K10483|1|0.0|1981|mmu:74007|BTB/POZ domain-containing protein 11 - - - gi|62953120|ref|NP_001017525.1|/0/ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform 2 [Mus musculus] 140721 4762 42.06 39.92666667 -0.075096218 Down 0.22582647 Caskin2 CASK-interacting protein 2 K14459|1|3e-32|144|apla:101799820|hexosaminidase [EC:3.2.1.52];K08848|3|1e-26|125|amj:102567026|receptor-interacting serine/threonine-protein kinase 4 [EC:2.7.11.1] GO:0044424 - - gi|37360258|dbj|BAC98107.1|/0/mKIAA1139 protein [Mus musculus] 226849 3082 39.92333333 42.05666667 0.075102328 Up 0.22582647 Ppp2r5a "protein phosphatase 2, regulatory subunit B', alpha" K11584|1|0.0|757|mmu:226849|serine/threonine-protein phosphatase 2A regulatory subunit B' GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0031672//A band;GO:0008287//protein serine/threonine phosphatase complex;GO:0031674//I band GO:0019888//protein phosphatase regulator activity;GO:0019899//enzyme binding GO:0006470//protein dephosphorylation;GO:0051129;GO:0033673//negative regulation of kinase activity;GO:0007154//cell communication gi|47059051|ref|NP_659129.2|/0/serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform [Mus musculus] 20168 2884.31 39.00333333 41.12333333 0.076359784 Up 0.225732446 Rtn3 reticulon 3 K08288|1|9e-62|241|chx:102186405|protein kinase C substrate 80K-H;K09029|2|2e-10|71.2|fpg:101920606|protein FosB GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0012505//endomembrane system;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0012505//endomembrane system;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0007029//endoplasmic reticulum organization;GO:0006810//transport;GO:0012501//programmed cell death;GO:0007029//endoplasmic reticulum organization;GO:0006810//transport;GO:0012501//programmed cell death;GO:0007029//endoplasmic reticulum organization;GO:0006810//transport;GO:0012501//programmed cell death;GO:0007029//endoplasmic reticulum organization;GO:0006810//transport;GO:0012501//programmed cell death;GO:0050896//response to stimulus;GO:0007029//endoplasmic reticulum organization;GO:0006810//transport;GO:0012501//programmed cell death gi|861460734|ref|XP_012931069.1|/3.18842e-99/PREDICTED: LOW QUALITY PROTEIN: reticulon-3-like [Heterocephalus glaber] 100503265 2856 0.506666667 0.336666667 -0.589716031 Down 0.225666629 Gm19619 "predicted gene, 19619" - - - - "gi|148673347|gb|EDL05294.1|/9.48674e-56/mCG144557, partial [Mus musculus]" 57429 1160 0.516666667 0.346666667 -0.575684687 Down 0.225666629 Sult5a1 "sulfotransferase family 5A, member 1" K01015|1|2e-151|537|ngi:103739992|alcohol sulfotransferase [EC:2.8.2.2] - GO:0003824//catalytic activity - "gi|755527072|ref|XP_011246761.1|/0/PREDICTED: sulfotransferase family 5A, member 1 isoform X3 [Mus musculus]" 54678 2666 0.526666667 0.353333333 -0.575860294 Down 0.225666629 Zfp108 zinc finger protein 108 K09228|1|0.0|1350|mmu:54678|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|157278011|ref|NP_061261.2|/0/zinc finger protein 108 [Mus musculus] 620419 2291 1.963333333 2.273333333 0.211504105 Up 0.22562902 Zfp963 zinc finger protein 963 K09228|1|0.0|837|mmu:620419|KRAB domain-containing zinc finger protein - - - gi|317108173|ref|NP_001186952.1|/0/zinc finger protein 669-like [Mus musculus] 235315 3534.51 11.16 11.98 0.102290881 Up 0.225610215 Rnf214 ring finger protein 214 - - - - "gi|29436408|gb|AAH49909.1|/0/Rnf214 protein, partial [Mus musculus]" 230584 1264.4 11.39333333 12.21333333 0.100267106 Up 0.225610215 Yipf1 "Yip1 domain family, member 1" - "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031224//intrinsic component of membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031224//intrinsic component of membrane" - - gi|326937436|ref|NP_001192085.1|/1.92361e-149/protein YIPF1 isoform 2 [Mus musculus] 69216 755.17 11.88666667 11.06666667 -0.103123461 Down 0.225610215 Svbp small vasohibin binding protein - - - - - 234964 3045 0.143333333 0.033333333 -2.10433666 Down 0.225600812 Ccdc67 coiled-coil domain containing 67 K16763|1|3e-48|196|aam:106493225|centrosomal protein CEP63 - - - gi|133778965|ref|NP_861537.2|/0/deuterosome protein 1 [Mus musculus] 100036520 1678 0.036666667 0.15 2.032421478 Up 0.225600812 Gata5os "GATA binding protein 5, opposite strand" K17896|1|2e-19|100|mmu:14464|GATA-binding protein 5 - - - - 74517 1758 0.033333333 0.143333333 2.10433666 Up 0.225600812 7420700N18Rik RIKEN cDNA 7420700N18 gene K16804|1|4e-25|119|mmu:218977|disks large-associated protein 5 - - - - 268721 6041.06 19.27 18.11333333 -0.089304507 Down 0.225544398 Zswim8 zinc finger SWIM-type containing 8 - - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - gi|355390253|ref|NP_001239010.1|/0/zinc finger SWIM domain-containing protein 8 isoform 2 [Mus musculus] 116733 2089 36.39666667 38.48666667 0.080552395 Up 0.225469179 Vps4a vacuolar protein sorting 4A K12196|1|0.0|843|rno:246772|vacuolar protein-sorting-associated protein 4 GO:0005770//late endosome;GO:0010008//endosome membrane GO:0032550;GO:0017016//Ras GTPase binding;GO:0016462//pyrophosphatase activity GO:0044763;GO:0045184//establishment of protein localization;GO:0044765//single-organism transport gi|676263289|gb|KFO20028.1|/0/Vacuolar protein sorting-associated protein 4A [Fukomys damarensis] 52665 2984.19 8.456666667 9.123333333 0.109471915 Up 0.225459777 Echdc1 enoyl Coenzyme A hydratase domain containing 1 K18426|1|1e-176|622|mmu:52665|ethylmalonyl-CoA/methylmalonyl-CoA decarboxylase [EC:4.1.1.94 4.1.1.41] - - - - 20289 1136 6.7 7.27 0.117794269 Up 0.225422167 Scx scleraxis K09070|1|5e-32|140|cmk:103188621|transcription factor 15 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0046983//protein dimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0008134//transcription factor binding GO:0051094//positive regulation of developmental process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0030198//extracellular matrix organization;GO:0051216//cartilage development;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0036075;GO:0007519//skeletal muscle tissue development;GO:0030154//cell differentiation;GO:0003179//heart valve morphogenesis;GO:0001704//formation of primary germ layer;GO:0048871//multicellular organismal homeostasis gi|38566694|ref|NP_942588.1|/1.41077e-71/basic helix-loop-helix transcription factor scleraxis [Mus musculus] 433667 2678 6.983333333 6.413333333 -0.122841445 Down 0.225422167 Ankrd13c ankyrin repeat domain 13c K16943|1|8e-57|224|tca:655956|septin 4;K05766|2|1e-55|220|ssc:100515297|protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48];K00910|3|2e-08|64.3|apla:101801089|beta-adrenergic-receptor kinase [EC:2.7.11.15];K10799|4|3e-07|60.1|amj:106736716|tankyrase [EC:2.4.2.30] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005515//protein binding GO:0042981//regulation of apoptotic process;GO:0010556;GO:0035437//maintenance of protein localization in endoplasmic reticulum gi|67972431|ref|NP_001013828.1|/0/ankyrin repeat domain-containing protein 13C [Mus musculus] 56312 639 7 6.426666667 -0.123284276 Down 0.225422167 Nupr1 nuclear protein transcription regulator 1 "K15626|1|8e-34|145|mmu:56312|nuclear protein, 1" GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0051726//regulation of cell cycle;GO:2000026//regulation of multicellular organismal development;GO:0040007//growth;GO:0008285//negative regulation of cell proliferation;GO:0042221//response to chemical;GO:0007519//skeletal muscle tissue development;GO:0043543;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0065003;GO:0008406//gonad development gi|9790145|ref|NP_062712.1|/5.62804e-33/nuclear protein 1 [Mus musculus] 18263 2547 34.93666667 37.00333333 0.082913271 Up 0.225375155 Odc1 "ornithine decarboxylase, structural 1" K01581|1|0.0|936|mmu:18263|ornithine decarboxylase [EC:4.1.1.17] GO:0044444//cytoplasmic part GO:0016831//carboxy-lyase activity GO:0051707//response to other organism;GO:0044767//single-organism developmental process;GO:0006591//ornithine metabolic process;GO:0006596//polyamine biosynthetic process;GO:0008283//cell proliferation gi|131888589|ref|NP_038642.2|/0/ornithine decarboxylase [Mus musculus] 70686 5039.37 4.24 3.82 -0.150491627 Down 0.225365753 Dusp16 dual specificity phosphatase 16 K04459|1|0.0|1256|rno:297682|dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005488//binding;GO:0042578//phosphoric ester hydrolase activity" GO:0006796//phosphate-containing compound metabolic process;GO:0000165//MAPK cascade;GO:0006796//phosphate-containing compound metabolic process;GO:0000165//MAPK cascade "gi|148678577|gb|EDL10524.1|/0/dual specificity phosphatase 16, isoform CRA_c, partial [Mus musculus]" 76438 2802 18.79666667 17.64333333 -0.091353689 Down 0.225299936 Rftn1 raftlin lipid raft linker 1 K07949|1|3e-08|63.5|cjc:100392687|ADP-ribosylation factor-like protein 5A GO:0044425 - - gi|74142212|dbj|BAE31871.1|/0/unnamed protein product [Mus musculus] 240832 3579.49 18.74 19.88666667 0.085680524 Up 0.225299936 Tor1aip2 torsin A interacting protein 2 - GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|11612513|ref|NP_071724.1|/2.06113e-70/interferon alpha responsive protein isoform a [Mus musculus] 15444 1568 0.186666667 0.333333333 0.836501268 Up 0.225149498 Hpca hippocalcin K19695|1|8e-96|353|cjo:107310436|neurocalcin delta - GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding GO:0043583//ear development;GO:0043583//ear development;GO:0043583//ear development;GO:0043583//ear development gi|635109717|ref|XP_007977726.1|/9.2487e-110/PREDICTED: neuron-specific calcium-binding protein hippocalcin isoform X1 [Chlorocebus sabaeus] 14180 4145 0.813333333 1.03 0.34072569 Up 0.22499906 Fgf9 fibroblast growth factor 9 K04358|1|5e-109|399|cge:100759509|fibroblast growth factor GO:0005578//proteinaceous extracellular matrix;GO:0044424 GO:0005539//glycosaminoglycan binding;GO:0070851//growth factor receptor binding "GO:0007224//smoothened signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0001501//skeletal system development;GO:0008406//gonad development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0042471//ear morphogenesis;GO:0006351//transcription, DNA-templated;GO:0001503//ossification;GO:0048565//digestive tract development;GO:0006886//intracellular protein transport;GO:0001570//vasculogenesis;GO:0035108//limb morphogenesis;GO:0040034//regulation of development, heterochronic;GO:0000165//MAPK cascade;GO:0003208//cardiac ventricle morphogenesis;GO:0030324//lung development" gi|25742766|ref|NP_037084.1|/4.27132e-108/fibroblast growth factor 9 precursor [Rattus norvegicus] 27045 1348.26 17.21 18.35 0.092532966 Up 0.224970853 Nit1 nitrilase 1 K13566|1|1e-46|189|mcf:101925059|omega-amidase [EC:3.5.1.3] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016787//hydrolase activity;GO:0016787//hydrolase activity GO:0008152//metabolic process;GO:0008152//metabolic process gi|6754856|ref|NP_036179.1|/0/nitrilase homolog 1 isoform 1 [Mus musculus] 620078 1971 0.19 0.336666667 0.825321469 Up 0.224942645 C130026I21Rik RIKEN cDNA C130026I21 gene K15413|1|1e-30|137|bacu:103004719|nuclear autoantigen Sp-100 - GO:0043169//cation binding - gi|126352632|ref|NP_001032998.2|/5.23845e-150/SP140 nuclear body protein family member isoform 2 [Mus musculus] 93890 4714 0.19 0.336666667 0.825321469 Up 0.224942645 Pcdhb19 protocadherin beta 19 K16494|1|0.0|1500|mmu:93890|protocadherin beta GO:0031224//intrinsic component of membrane - GO:0022610 gi|89363034|ref|NP_444374.2|/0/protocadherin beta 19 precursor [Mus musculus] 17245 3159.78 1.213333333 1.463333333 0.270282489 Up 0.224839219 Mdm1 transformed mouse 3T3 cell double minute 1 K17886|1|0.0|1279|mmu:17245|nuclear protein MDM1 - - GO:0043010//camera-type eye development;GO:0043010//camera-type eye development;GO:0043010//camera-type eye development;GO:0043010//camera-type eye development gi|251823814|ref|NP_001156376.1|/0/nuclear protein MDM1 isoform 3 [Mus musculus] 12162 3670 1.206666667 1.453333333 0.268338438 Up 0.224839219 Bmp7 bone morphogenetic protein 7 K16621|1|0.0|884|rno:85272|bone morphogenetic protein 7 GO:0044421;GO:0031982//vesicle GO:0070696//transmembrane receptor protein serine/threonine kinase binding;GO:0005539//glycosaminoglycan binding GO:0007067//mitotic nuclear division;GO:0001934//positive regulation of protein phosphorylation;GO:0060442//branching involved in prostate gland morphogenesis;GO:0060562//epithelial tube morphogenesis;GO:0072075//metanephric mesenchyme development;GO:0001704//formation of primary germ layer;GO:0035108//limb morphogenesis;GO:0022409//positive regulation of cell-cell adhesion;GO:0030282//bone mineralization;GO:0007219//Notch signaling pathway;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0010976//positive regulation of neuron projection development;GO:0090322//regulation of superoxide metabolic process;GO:0070486//leukocyte aggregation;GO:0051726//regulation of cell cycle;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0006935//chemotaxis;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0000904//cell morphogenesis involved in differentiation;GO:0072110//glomerular mesangial cell proliferation;GO:0001649//osteoblast differentiation;GO:0001666//response to hypoxia;GO:0010721//negative regulation of cell development;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0048704//embryonic skeletal system morphogenesis;GO:0031076//embryonic camera-type eye development;GO:0043627//response to estrogen;GO:0042476//odontogenesis;GO:0009755//hormone-mediated signaling pathway;GO:0007435//salivary gland morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0072076//nephrogenic mesenchyme development;GO:0043405//regulation of MAP kinase activity gi|31982487|ref|NP_031583.2|/0/bone morphogenetic protein 7 preproprotein [Mus musculus] 20292 1073 1.456666667 1.206666667 -0.271643582 Down 0.224839219 Ccl11 chemokine (C-C motif) ligand 11 K16597|1|6e-38|160|mmu:20292|C-C motif chemokine 11 GO:0044421 GO:0005125//cytokine activity GO:0006954//inflammatory response;GO:0001935//endothelial cell proliferation;GO:0060560//developmental growth involved in morphogenesis;GO:0009628//response to abiotic stimulus;GO:0048754//branching morphogenesis of an epithelial tube;GO:0030595//leukocyte chemotaxis;GO:0022610;GO:0001525//angiogenesis;GO:0006464//cellular protein modification process;GO:0022604//regulation of cell morphogenesis;GO:0030041//actin filament polymerization;GO:0000165//MAPK cascade;GO:0034097//response to cytokine;GO:0006875//cellular metal ion homeostasis;GO:0051707//response to other organism gi|6755418|ref|NP_035460.1|/4.61186e-37/eotaxin precursor [Mus musculus] 12335 3094.89 1.206666667 1.453333333 0.268338438 Up 0.224839219 Capn3 calpain 3 K08573|1|0.0|1484|cge:100758723|calpain-3 [EC:3.4.22.54] GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0042383//sarcolemma;GO:0031674//I band;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0042383//sarcolemma;GO:0031674//I band GO:0030234//enzyme regulator activity;GO:0005198//structural molecule activity;GO:0004197//cysteine-type endopeptidase activity;GO:0031420;GO:0008092//cytoskeletal protein binding;GO:0030234//enzyme regulator activity;GO:0005198//structural molecule activity;GO:0004197//cysteine-type endopeptidase activity;GO:0031420;GO:0008092//cytoskeletal protein binding GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0016925//protein sumoylation;GO:0045445//myoblast differentiation;GO:0006915//apoptotic process;GO:0030239//myofibril assembly;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0009651//response to salt stress;GO:0006508//proteolysis;GO:0014717//regulation of satellite cell activation involved in skeletal muscle regeneration;GO:0051592//response to calcium ion;GO:0014823//response to activity;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0065003;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0016925//protein sumoylation;GO:0045445//myoblast differentiation;GO:0006915//apoptotic process;GO:0030239//myofibril assembly;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0009651//response to salt stress;GO:0006508//proteolysis;GO:0014717//regulation of satellite cell activation involved in skeletal muscle regeneration;GO:0051592//response to calcium ion;GO:0014823//response to activity;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0065003 gi|295317368|ref|NP_001171270.1|/0/calpain-3 isoform c [Mus musculus] 78825 4214 4.403333333 4.856666667 0.141370411 Up 0.224811012 Desi2 desumoylating isopeptidase 2 - GO:0044424 GO:0016787//hydrolase activity GO:0019538//protein metabolic process gi|947289637|ref|XP_006157297.2|/2.16462e-99/PREDICTED: desumoylating isopeptidase 2 [Tupaia chinensis] 54402 1078 4.506666667 4.953333333 0.136338964 Up 0.224811012 Stk19 serine/threonine kinase 19 K08880|1|5e-141|503|mmu:54402|serine/threonine kinase 19 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|9507153|ref|NP_062315.1|/3.82362e-140/serine/threonine-protein kinase 19 [Mus musculus] 66801 1654 4.476666667 4.93 0.139162748 Up 0.224811012 Prkrip1 Prkr interacting protein 1 (IL11 inducible) - GO:0031981//nuclear lumen GO:0019900//kinase binding;GO:0019887//protein kinase regulator activity GO:0001933//negative regulation of protein phosphorylation gi|13385244|ref|NP_080050.1|/8.28442e-56/PRKR-interacting protein 1 [Mus musculus] 117197 1306 4.893333333 4.446666667 -0.138093302 Down 0.224811012 Bloc1s4 "biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino" K08366|1|6e-99|363|mmu:117197|biogenesis of lysosome-related organelles complex 1 subunit 4 - - - - 320244 4858 4.9 4.453333333 -0.137896147 Down 0.224811012 Ttll5 "tubulin tyrosine ligase-like family, member 5" K16602|1|0.0|2404|mmu:320244|tubulin polyglutamylase TTLL5 [EC:6.-.-.-] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0016881//acid-amino acid ligase activity GO:0010467//gene expression;GO:0036211//protein modification process "gi|148670942|gb|EDL02889.1|/0/mCG121822, isoform CRA_g, partial [Mus musculus]" 26414 6577.87 4.433333333 4.88 0.138489308 Up 0.224811012 Mapk10 mitogen-activated protein kinase 10 K04440|1|0.0|844|tup:102475730|c-Jun N-terminal kinase [EC:2.7.11.24] - - - - 228836 4097.64 33.19333333 35.20666667 0.084955126 Up 0.224792207 Dlgap4 "discs, large homolog-associated protein 4 (Drosophila)" "K15008|1|4e-167|592|lcm:102346037|discs, large-associated protein 1" GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding - gi|109891940|ref|NP_001035952.1|/0/disks large-associated protein 4 isoform b [Mus musculus] 242022 12368 0.423333333 0.603333333 0.5111612 Up 0.224764 Frem2 Fras1 related extracellular matrix protein 2 K08115|1|9e-64|250|tru:101065472|chondroitin sulfate proteoglycan 4 GO:0031224//intrinsic component of membrane;GO:0005578//proteinaceous extracellular matrix GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion;GO:0043583//ear development;GO:0048729//tissue morphogenesis gi|71051607|ref|NP_766450.2|/0/FRAS1-related extracellular matrix protein 2 precursor [Mus musculus] 16569 5647 2.17 2.493333333 0.200380727 Up 0.224764 Kif3b kinesin family member 3B K20196|1|0.0|1127|mmu:16569|kinesin family member 3B GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005871//kinesin complex;GO:0044444//cytoplasmic part GO:0032550;GO:0003777//microtubule motor activity;GO:0017016//Ras GTPase binding GO:0007599//hemostasis;GO:0007052//mitotic spindle organization;GO:0009855//determination of bilateral symmetry;GO:0047496//vesicle transport along microtubule;GO:0007067//mitotic nuclear division;GO:0008088//axo-dendritic transport;GO:0002478 gi|28972173|dbj|BAC65540.1|/0/mKIAA0359 protein [Mus musculus] 69994 2154 2.09 2.406666667 0.203533394 Up 0.224764 Rsc1a1 "regulatory solute carrier protein, family 1, member 1" K11885|1|2e-171|605|ngi:103725332|DNA damage-inducible protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0016020//membrane - "GO:0006810//transport;GO:0006351//transcription, DNA-templated;GO:0022600//digestive system process" gi|77404400|ref|NP_076033.4|/0/regulatory solute carrier protein family 1 member 1 [Mus musculus] 72825 2112 8.273333333 8.936666667 0.111268104 Up 0.224716988 Mon1a "MON1 homolog A, secretory traffciking associated" K20195|1|0.0|1050|mmu:72825|vacuolar fusion protein MON1 - - GO:0015031//protein transport;GO:0006875//cellular metal ion homeostasis gi|21312179|ref|NP_082645.1|/0/vacuolar fusion protein MON1 homolog A [Mus musculus] 545261 606 8.036666667 8.696666667 0.113865293 Up 0.224716988 Bvht braveheart long non-coding RNA - - - - - 73132 3141 7.993333333 8.65 0.11390288 Up 0.224716988 Slc25a16 "solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16" "K15084|1|7e-179|630|mmu:73132|solute carrier family 25 (mitochondrial carrier protein), member 16" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763 gi|30424808|ref|NP_780403.1|/6.38846e-178/graves disease carrier protein homolog [Mus musculus] 70118 1134 8.713333333 9.376666667 0.105850412 Up 0.224716988 Srrd SRR1 domain containing K02886|1|2e-13|79.0|tsp:Tsp_03164|large subunit ribosomal protein L2 - - - "gi|148688028|gb|EDL19975.1|/8.73688e-160/mCG3486, isoform CRA_c [Mus musculus]" 108699 4003.47 8.243333333 8.903333333 0.111117736 Up 0.224716988 Chn1 chimerin 1 "K02649|1|9e-38|162|bfo:BRAFLDRAFT_91712|phosphoinositide-3-kinase, regulatory subunit;K10360|2|6e-37|159|tca:656579|myosin IX" GO:0044464;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044464 "GO:0005102//receptor binding;GO:0008047//enzyme activator activity;GO:0043169//cation binding;GO:0005102//receptor binding;GO:0008047//enzyme activator activity;GO:0030674//protein binding, bridging;GO:0043169//cation binding;GO:0005102//receptor binding;GO:0008047//enzyme activator activity;GO:0030674//protein binding, bridging;GO:0043169//cation binding;GO:0005102//receptor binding;GO:0008047//enzyme activator activity;GO:0030674//protein binding, bridging;GO:0043169//cation binding;GO:0005102//receptor binding;GO:0043169//cation binding" GO:0007411//axon guidance;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007411//axon guidance;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007411//axon guidance;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007411//axon guidance;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007411//axon guidance;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|262205438|ref|NP_001160076.1|/2.17134e-156/N-chimaerin isoform 5 [Mus musculus] 14587 1997 1.07 1.306666667 0.288280357 Up 0.224679379 Gfra3 glial cell line derived neurotrophic factor family receptor alpha 3 K19895|1|2e-55|219|ola:101167523|GDNF family receptor alpha 1 - - - - 192185 3053 16.74 17.86666667 0.093970972 Up 0.224669976 Nadk NAD kinase K00858|1|0.0|865|mmu:192185|NAD+ kinase [EC:2.7.1.23] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0032550;GO:0016301//kinase activity;GO:0043169//cation binding;GO:0032550;GO:0016301//kinase activity GO:0006739//NADP metabolic process;GO:0006739//NADP metabolic process gi|564354392|ref|XP_006239575.1|/0/PREDICTED: NAD kinase isoform X2 [Rattus norvegicus] 319945 2223 36.53666667 34.55333333 -0.080520126 Down 0.22460416 Flad1 flavin adenine dinucleotide synthetase 1 K00953|1|0.0|998|mmu:319945|FAD synthetase [EC:2.7.7.2] - - - - 433638 1066 0.426666667 0.266666667 -0.678071905 Down 0.22456655 I830077J02Rik RIKEN cDNA I830077J02 gene - GO:0031224//intrinsic component of membrane - - gi|85702091|ref|NP_001028952.1|/2.04133e-53/transmembrane protein C1orf162 homolog [Mus musculus] 20856 1793 7.053333333 6.49 -0.120086743 Down 0.22440671 Stc2 stanniocalcin 2 - GO:0043231//intracellular membrane-bounded organelle GO:0005102//receptor binding GO:0001666//response to hypoxia;GO:0009725//response to hormone;GO:0033554//cellular response to stress;GO:0051924//regulation of calcium ion transport;GO:0001893//maternal placenta development;GO:0035264//multicellular organism growth;GO:0006875//cellular metal ion homeostasis;GO:0014070//response to organic cyclic compound;GO:0010966//regulation of phosphate transport;GO:0006984//ER-nucleus signaling pathway gi|6755676|ref|NP_035621.1|/6.37016e-166/stanniocalcin-2 precursor [Mus musculus] 76366 4982.04 6.706666667 7.27 0.116359465 Up 0.22440671 Mtif3 mitochondrial translational initiation factor 3 K02520|1|7e-148|528|mmu:76366|translation initiation factor IF-3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding;GO:0043021//ribonucleoprotein complex binding;GO:0003723//RNA binding;GO:0043021//ribonucleoprotein complex binding;GO:0003723//RNA binding;GO:0043021//ribonucleoprotein complex binding;GO:0003723//RNA binding;GO:0043021//ribonucleoprotein complex binding GO:0006413//translational initiation;GO:0032988;GO:0006413//translational initiation;GO:0032988;GO:0006413//translational initiation;GO:0032988;GO:0006413//translational initiation;GO:0032988 "gi|21313176|ref|NP_083857.1|/5.87269e-147/translation initiation factor IF-3, mitochondrial [Mus musculus]" 18108 4461 2.956666667 2.606666667 -0.181765497 Down 0.224378502 Nmt2 N-myristoyltransferase 2 K00671|1|0.0|1027|mmu:18108|glycylpeptide N-tetradecanoyltransferase [EC:2.3.1.97] - - - - 233280 1885 2.646666667 2.993333333 0.177576438 Up 0.224378502 Nipa1 non imprinted in Prader-Willi/Angelman syndrome 1 homolog (human) K19364|1|3e-146|521|hgl:101714525|magnesium transporter NIPA1 GO:0005768//endosome;GO:0031224//intrinsic component of membrane GO:0046873//metal ion transmembrane transporter activity GO:0070838//divalent metal ion transport gi|41406091|ref|NP_653200.2|/2.96838e-145/magnesium transporter NIPA1 isoform 1 [Homo sapiens] 16570 6849 2.896666667 2.55 -0.183896429 Down 0.224378502 Kif3c kinesin family member 3C K20197|1|0.0|1297|mmu:16570|kinesin family member 3C - - - - 16534 1956 0.2 0.35 0.807354922 Up 0.2243691 Kcnn4 "potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4" K04945|1|0.0|695|mmu:16534|potassium intermediate/small conductance calcium-activated channel subfamily N member 4 GO:0044297//cell body;GO:0016021//integral component of membrane;GO:0044459;GO:0044297//cell body;GO:0016021//integral component of membrane;GO:0044459 GO:0015269//calcium-activated potassium channel activity;GO:0019902//phosphatase binding;GO:0015269//calcium-activated potassium channel activity;GO:0019902//phosphatase binding GO:0007589//body fluid secretion;GO:0009306//protein secretion;GO:0015914//phospholipid transport;GO:0071805//potassium ion transmembrane transport;GO:0050852//T cell receptor signaling pathway;GO:0070838//divalent metal ion transport;GO:0042391//regulation of membrane potential;GO:0007589//body fluid secretion;GO:0009306//protein secretion;GO:0015914//phospholipid transport;GO:0071805//potassium ion transmembrane transport;GO:0050852//T cell receptor signaling pathway;GO:0070838//divalent metal ion transport;GO:0042391//regulation of membrane potential gi|254553464|ref|NP_032459.3|/0/intermediate conductance calcium-activated potassium channel protein 4 [Mus musculus] 72578 4319.05 0.2 0.35 0.807354922 Up 0.2243691 2700054A10Rik RIKEN cDNA 2700054A10 gene - - - - - 76123 3510 0.696666667 0.903333333 0.374789909 Up 0.2243691 Gpsm2 "G-protein signalling modulator 2 (AGS3-like, C. elegans)" K15837|1|0.0|1333|mmu:76123|G-protein signaling modulator 2 GO:0044424 GO:0005515//protein binding GO:0030855//epithelial cell differentiation;GO:0007186//G-protein coupled receptor signaling pathway gi|164519124|ref|NP_083798.2|/0/G-protein-signaling modulator 2 [Mus musculus] 16420 4894 0.706666667 0.913333333 0.370111628 Up 0.2243691 Itgb6 integrin beta 6 K06589|1|0.0|1562|mmu:16420|integrin beta 6 GO:0005887//integral component of plasma membrane;GO:0005887//integral component of plasma membrane GO:0005102//receptor binding;GO:0005102//receptor binding GO:0032502//developmental process;GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway;GO:0031589//cell-substrate adhesion;GO:0032502//developmental process;GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway;GO:0031589//cell-substrate adhesion gi|10946686|ref|NP_067334.1|/0/integrin beta-6 precursor [Mus musculus] 76055 4797 19.00666667 17.89 -0.087352151 Down 0.22433149 Mgea5 meningioma expressed antigen 5 (hyaluronidase) K15719|1|0.0|1807|mmu:76055|protein O-GlcNAcase / histone acetyltransferase [EC:3.2.1.169 2.3.1.48] GO:0043231//intracellular membrane-bounded organelle GO:0004563//beta-N-acetylhexosaminidase activity;GO:0008080//N-acetyltransferase activity GO:0006486//protein glycosylation;GO:0016570//histone modification;GO:0032846;GO:0010828//positive regulation of glucose transport;GO:0030252//growth hormone secretion;GO:0009151;GO:0010522//regulation of calcium ion transport into cytosol;GO:0006259//DNA metabolic process;GO:0006508//proteolysis;GO:0006605//protein targeting;GO:0010612;GO:0008219//cell death;GO:0043241//protein complex disassembly;GO:0050796//regulation of insulin secretion;GO:1901071;GO:0044767//single-organism developmental process;GO:0009725//response to hormone;GO:0001906//cell killing gi|37360040|dbj|BAC97998.1|/0/mKIAA0679 protein [Mus musculus] 103199 3278 18.63 17.51 -0.089448591 Down 0.22433149 Fig4 FIG4 phosphoinositide 5-phosphatase K20279|1|2e-29|134|pale:102890440|synaptojanin [EC:3.1.3.36] - - - - 66771 4437 19.41333333 18.29666667 -0.085467016 Down 0.22433149 Gid4 "GID complex subunit 4, VID24 homolog" - - - - - 53867 6135 5.873333333 5.38 -0.126573346 Down 0.224256271 Col5a3 "collagen, type V, alpha 3" "K19721|1|0.0|793|mmu:53867|collagen, type V/XI/XXIV/XXVII, alpha" - - - - 56336 4205 3.256666667 3.65 0.164500403 Up 0.224209259 B4galt5 "UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5" "K09905|1|0.0|703|mmu:56336|beta-1,4-galactosyltransferase 5 [EC:2.4.1.-]" GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane "GO:0043169//cation binding;GO:0016758//transferase activity, transferring hexosyl groups" GO:0006024//glycosaminoglycan biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0006493//protein O-linked glycosylation;GO:0006487//protein N-linked glycosylation "gi|7634678|dbj|BAA94791.1|/0/beta-1,4-galactosyltransferase V [Mus musculus]" 73458 1999 0.116666667 0.25 1.099535674 Up 0.224181052 Aldh3b3 "aldehyde dehydrogenase 3 family, member B3" K00129|1|0.0|972|mmu:73458|aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5] - - - - 13110 3595 2.056666667 1.766666667 -0.21927813 Down 0.224152845 Cyp2j6 "cytochrome P450, family 2, subfamily j, polypeptide 6" "K07418|1|0.0|992|mmu:13110|cytochrome P450, family 2, subfamily J [EC:1.14.14.1]" GO:0043231//intracellular membrane-bounded organelle "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0008392//arachidonic acid epoxygenase activity;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0016653//oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor" GO:0019369//arachidonic acid metabolic process;GO:0010033//response to organic substance gi|160948618|ref|NP_034138.3|/0/cytochrome P450 2J6 [Mus musculus] 20444 4470 9.21 8.556666667 -0.106152266 Down 0.224124638 St3gal2 "ST3 beta-galactoside alpha-2,3-sialyltransferase 2" "K03368|1|0.0|742|mmu:20444|beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4B) [EC:2.4.99.4]" GO:0031228//intrinsic component of Golgi membrane GO:0008373//sialyltransferase activity GO:0006464//cellular protein modification process "gi|589922499|ref|XP_006974157.1|/0/PREDICTED: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 isoform X1 [Peromyscus maniculatus bairdii] " 100042498 1766 8.296666667 8.95 0.109355858 Up 0.224124638 Mir22hg Mir22 host gene (non-protein coding) - - - - "gi|148680867|gb|EDL12814.1|/1.17792e-47/RIKEN cDNA 2010305C02, isoform CRA_b, partial [Mus musculus]" 67974 4017 35.30333333 33.37333333 -0.081108619 Down 0.224087028 Ccny cyclin Y "K18468|1|3e-45|187|rro:104674309|vacuolar protein sorting-associated protein 35;K12491|3|1e-16|92.0|nle:100586848|Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3" - - - - 14026 2124.18 18.09 19.19666667 0.085663413 Up 0.2239742 Evl Ena-vasodilator stimulated phosphoprotein K05746|1|1e-73|280|umr:103669072|enabled GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0043232;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0043232;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0043232;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0043232 GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding GO:0006928//movement of cell or subcellular component;GO:0006935//chemotaxis;GO:0051693//actin filament capping;GO:0001775//cell activation;GO:0051260//protein homooligomerization;GO:0006928//movement of cell or subcellular component;GO:0006935//chemotaxis;GO:0051693//actin filament capping;GO:0007399//nervous system development;GO:0001775//cell activation;GO:0051260//protein homooligomerization;GO:0006928//movement of cell or subcellular component;GO:0006935//chemotaxis;GO:0051693//actin filament capping;GO:0007399//nervous system development;GO:0001775//cell activation;GO:0051260//protein homooligomerization;GO:0006928//movement of cell or subcellular component;GO:0006935//chemotaxis;GO:0051693//actin filament capping;GO:0001775//cell activation;GO:0051260//protein homooligomerization gi|254281247|ref|NP_001156867.1|/2.84605e-180/ena/VASP-like protein isoform 3 [Mus musculus] 54610 4451 2.266666667 2.593333333 0.194235409 Up 0.223833164 Tbc1d8 "TBC1 domain family, member 8" K19951|1|0.0|1986|mcc:710649|TBC1 domain family member 9 GO:0044464 GO:0046872//metal ion binding - gi|224809347|ref|NP_061245.3|/0/TBC1 domain family member 8 [Mus musculus] 52013 3979 2.363333333 2.693333333 0.188569666 Up 0.223833164 R3hcc1l R3H domain and coiled-coil containing 1 like "K07412|1|1e-27|128|chx:102177329|cytochrome P450, family 2, subfamily B [EC:1.14.14.1]" - - - gi|29126193|ref|NP_803415.1|/0/coiled-coil domain-containing protein R3HCC1L [Mus musculus] 110417 2376 3.8 4.206666667 0.146678086 Up 0.223804957 Pigh "phosphatidylinositol glycan anchor biosynthesis, class H" "K03858|1|3e-102|375|mmu:110417|phosphatidylinositol glycan, class H" GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0031090//organelle membrane GO:0008375//acetylglucosaminyltransferase activity GO:0006506//GPI anchor biosynthetic process gi|755542131|ref|XP_011242289.1|/5.37446e-110/PREDICTED: phosphatidylinositol N-acetylglucosaminyltransferase subunit H isoform X1 [Mus musculus] 76737 1364 10.43 11.21333333 0.104476047 Up 0.223729738 Creld2 cysteine-rich with EGF-like domains 2 K17675|1|4e-45|184|tsp:Tsp_02850|ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:3.6.4.13];K19013|2|5e-24|114|mmu:192188|stabilin-2 GO:0044421;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding - gi|21313278|ref|NP_083996.1|/0/cysteine-rich with EGF-like domain protein 2 precursor [Mus musculus] 52808 2776 10.89666667 11.67666667 0.099741611 Up 0.223729738 Tspyl2 TSPY-like 2 K11285|1|0.0|965|mmu:52808|TSPY-like 2 GO:0031981//nuclear lumen - "GO:0001932//regulation of protein phosphorylation;GO:0016049//cell growth;GO:0006260//DNA replication;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" gi|33859738|ref|NP_084112.1|/0/testis-specific Y-encoded-like protein 2 [Mus musculus] 72657 685.64 12.06 11.27666667 -0.096889231 Down 0.223729738 2700094K13Rik RIKEN cDNA 2700094K13 gene - - - GO:0019725//cellular homeostasis;GO:0019725//cellular homeostasis gi|76781489|ref|NP_001028338.1|/6.74819e-49/selenoprotein H [Mus musculus] 66618 836 32.96666667 34.86 0.080564549 Up 0.223710933 Snrnp27 small nuclear ribonucleoprotein 27 (U4/U6.U5) K12846|1|4e-23|110|pale:102890151|U4/U6.U5 tri-snRNP-associated protein 3 GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex GO:0097159//organic cyclic compound binding GO:0006396//RNA processing gi|73970255|ref|XP_531856.2|/3.55788e-22/PREDICTED: U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein [Canis lupus familiaris] 56397 1818.09 34.15 32.26 -0.08213914 Down 0.223710933 Morf4l2 mortality factor 4 like 2 K11342|1|3e-163|577|mmu:56397|mortality factor 4-like protein 2 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0040007//growth;GO:0051146//striated muscle cell differentiation;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0040007//growth;GO:0051146//striated muscle cell differentiation;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0040007//growth;GO:0051146//striated muscle cell differentiation;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0040007//growth;GO:0051146//striated muscle cell differentiation;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0040007//growth;GO:0051146//striated muscle cell differentiation;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0040007//growth;GO:0051146//striated muscle cell differentiation;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0040007//growth;GO:0051146//striated muscle cell differentiation;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter gi|269996025|ref|NP_062742.4|/2.79305e-162/mortality factor 4-like protein 2 [Mus musculus] 102466804 79 1.196666667 0.963333333 -0.312914351 Down 0.223663921 Mir7091 microRNA 7091 - - - - - 66454 954 17.96 19.05666667 0.085508439 Up 0.223645116 Nmnat1 nicotinamide nucleotide adenylyltransferase 1 K06210|1|5e-165|582|mmu:66454|nicotinamide mononucleotide adenylyltransferase [EC:2.7.7.1 2.7.7.18] GO:0043231//intracellular membrane-bounded organelle GO:0070566//adenylyltransferase activity GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0006950//response to stress "gi|10442021|gb|AAG17286.1|AF260925_1/1.35379e-175/D4COLE1E, partial [Mus musculus]" 217615 2873.42 18.14666667 19.25 0.08515388 Up 0.223645116 Ctage5 "CTAGE family, member 5" K11849|1|3e-17|93.6|ecb:100147361|ubiquitin carboxyl-terminal hydrolase 25/28 [EC:3.4.19.12];K20478|2|3e-12|77.0|sko:100376626|golgin subfamily B member 1;K17975|3|5e-12|76.3|nle:100594255|kinectin;K16551|4|2e-11|73.9|crg:105330473|A-kinase anchor protein 9 GO:0031224//intrinsic component of membrane;GO:0016020//membrane;GO:0016020//membrane - - gi|259155338|ref|NP_001158726.1|/0/cTAGE family member 5 isoform 3 [Mus musculus] 20447 3885 0.61 0.43 -0.504472583 Down 0.223616909 St6galnac3 "ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3" "K03373|1|0.0|649|mmu:20447|N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7C) [EC:2.4.99.-]" - - - - 231986 2925 1.476666667 1.23 -0.263685882 Down 0.223598104 Jazf1 JAZF zinc finger 1 K19495|1|2e-104|383|rno:685879|juxtaposed with another zinc finger protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0006366//transcription from RNA polymerase II promoter gi|701358456|ref|XP_010005940.1|/1.49523e-80/PREDICTED: juxtaposed with another zinc finger protein 1 [Chaetura pelagica] 22092 1164 0.61 0.81 0.409112665 Up 0.223560495 Rsph1 radial spoke head 1 homolog (Chlamydomonas) K19755|1|3e-153|543|mmu:22092|radial spoke head protein 1 GO:0044444//cytoplasmic part;GO:0043232 - GO:0022403 gi|13384638|ref|NP_079566.1|/2.86426e-152/radial spoke head 1 homolog [Mus musculus] 225467 2736 0.81 0.61 -0.409112665 Down 0.223560495 Pggt1b "protein geranylgeranyltransferase type I, beta subunit" K11713|1|0.0|782|mmu:225467|geranylgeranyl transferase type-1 subunit beta [EC:2.5.1.59] - - - - 16640 1194 1.086666667 0.863333333 -0.331919867 Down 0.22354169 Klra9 "killer cell lectin-like receptor subfamily A, member 9" K10069|1|8e-20|100|myb:106725970|C-type lectin domain family 1 member A;K17517|2|2e-19|99.0|ocu:100342539|C-type lectin domain family 12 member B;K10074|3|2e-18|95.9|ocu:100339146|C-type lectin domain family 7 member A GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0051707//response to other organism;GO:0022610 "gi|133922571|ref|NP_034781.2|/1.25001e-158/killer cell lectin-like receptor subfamily A, member 9 [Mus musculus]" 76487 2320 0.276666667 0.436666667 0.65838357 Up 0.223522885 Ppp1r3g "protein phosphatase 1, regulatory (inhibitor) subunit 3G" K07189|1|4e-30|135|lcm:102351949|protein phosphatase 1 regulatory subunit 3A/B/C/D/E - GO:0030247//polysaccharide binding;GO:0019902//phosphatase binding GO:0051347//positive regulation of transferase activity;GO:0005978//glycogen biosynthetic process;GO:0033500//carbohydrate homeostasis gi|223278390|ref|NP_083904.1|/0/protein phosphatase 1 regulatory subunit 3G [Mus musculus] 15278 2448 32.30333333 34.16666667 0.080906462 Up 0.223504081 Tfb2m "transcription factor B2, mitochondrial" "K17653|1|0.0|790|mmu:15278|dimethyladenosine transferase 2, mitochondrial [EC:2.1.1.-]" GO:0005759//mitochondrial matrix "GO:0000989//transcription factor activity, transcription factor binding;GO:0008173//RNA methyltransferase activity;GO:0008170//N-methyltransferase activity" "GO:0000959//mitochondrial RNA metabolic process;GO:0000154//rRNA modification;GO:0006352//DNA-templated transcription, initiation" "gi|84490373|ref|NP_032275.2|/0/dimethyladenosine transferase 2, mitochondrial [Mus musculus]" 140570 6518.72 32.54666667 30.7 -0.084271139 Down 0.223438264 Plxnb2 plexin B2 K06821|1|0.0|3692|mmu:140570|plexin B GO:0044464;GO:0016021//integral component of membrane;GO:0044464;GO:0016021//integral component of membrane GO:0004888//transmembrane signaling receptor activity;GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity;GO:0005488//binding GO:0001764//neuron migration;GO:0007166//cell surface receptor signaling pathway;GO:0022604//regulation of cell morphogenesis;GO:0007417//central nervous system development;GO:0007409//axonogenesis;GO:0006468//protein phosphorylation;GO:0001764//neuron migration;GO:0007166//cell surface receptor signaling pathway;GO:0022604//regulation of cell morphogenesis;GO:0007417//central nervous system development;GO:0007409//axonogenesis;GO:0006468//protein phosphorylation gi|226958474|ref|NP_620088.2|/0/plexin-B2 precursor [Mus musculus] 50724 1549 16.62 17.71 0.09164383 Up 0.223428862 Sap30l SAP30-like K19202|1|3e-92|341|pale:102898396|histone deacetylase complex subunit SAP30 GO:0031981//nuclear lumen GO:0043169//cation binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" "gi|63102312|gb|AAH94930.1|/5.34562e-94/Sap30l protein, partial [Mus musculus]" 20227 5091 16.25666667 17.34333333 0.093349735 Up 0.223428862 Sart1 squamous cell carcinoma antigen recognized by T cells 1 K11984|1|0.0|1171|mmu:20227|U4/U6.U5 tri-snRNP-associated protein 1 GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0044444//cytoplasmic part GO:0005488//binding "GO:0045065//cytotoxic T cell differentiation;GO:0022402//cell cycle process;GO:0000398//mRNA splicing, via spliceosome;GO:0035556//intracellular signal transduction" gi|124244096|ref|NP_058578.3|/0/U4/U6.U5 tri-snRNP-associated protein 1 [Mus musculus] 330788 5780 1.35 1.61 0.254101281 Up 0.223419459 Zfp866 zinc finger protein 866 K09228|1|0.0|1138|mmu:330788|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|141801938|ref|NP_808567.2|/0/zinc finger protein 866 [Mus musculus] 18700 3593 0.713333333 0.526666667 -0.437686238 Down 0.22338185 Piga "phosphatidylinositol glycan anchor biosynthesis, class A" "K03857|1|0.0|896|mmu:18700|phosphatidylinositol glycan, class A [EC:2.4.1.198]" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0016740//transferase activity GO:0006497//protein lipidation gi|126273666|ref|NP_035211.2|/0/N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein [Mus musculus] 104401 7281 4.85 4.413333333 -0.136116031 Down 0.223372447 Pcnx3 pecanex homolog 3 - - - - gi|157743254|ref|NP_659117.2|/0/pecanex-like protein 3 [Mus musculus] 16400 4705.05 4.81 4.37 -0.138403614 Down 0.223372447 Itga3 integrin alpha 3 K06482|1|0.0|2016|mmu:16400|integrin alpha 3 GO:0005887//integral component of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005887//integral component of plasma membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0022610;GO:0007338//single fertilization;GO:0007611//learning or memory;GO:0007166//cell surface receptor signaling pathway;GO:0022610;GO:0007338//single fertilization;GO:0007611//learning or memory;GO:0007166//cell surface receptor signaling pathway;GO:0022610;GO:0007338//single fertilization;GO:0007611//learning or memory gi|807201190|ref|NP_001293000.1|/0/integrin alpha-3 isoform 2 [Mus musculus] 93736 10165 4.68 4.236666667 -0.143578905 Down 0.223372447 Aff4 "AF4/FMR2 family, member 4" K15185|1|0.0|1696|mmu:93736|AF4/FMR2 family member 4 GO:0031981//nuclear lumen GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0007281//germ cell development;GO:0006351//transcription, DNA-templated" gi|17298672|ref|NP_291043.1|/0/AF4/FMR2 family member 4 [Mus musculus] 69553 2935 0.203333333 0.353333333 0.797183117 Up 0.223316033 Fam65c "family with sequence similarity 65, member C" - - - - gi|123959722|ref|NP_001074177.1|/0/protein FAM65C [Mus musculus] 67532 3419 11.2 11.97 0.09592442 Up 0.223316033 Mfap1a microfibrillar-associated protein 1A K13110|1|3e-142|509|mmu:100034361|microfibrillar-associated protein 1 GO:0043205//fibril - - gi|26328395|dbj|BAC27936.1|/1.84925e-178/unnamed protein product [Mus musculus] 63872 1530 0.36 0.206666667 -0.800691192 Down 0.223316033 Zfp296 zinc finger protein 296 K09228|1|2e-25|119|bom:102285626|KRAB domain-containing zinc finger protein - - - gi|294997324|ref|NP_071854.2|/0/zinc finger protein 296 [Mus musculus] 212439 2940 0.613333333 0.81 0.401250548 Up 0.223278423 AA986860 expressed sequence AA986860 - GO:0044424;GO:0016020//membrane - - gi|162417980|ref|NP_808272.2|/0/specifically androgen-regulated gene protein [Mus musculus] 282619 1925.19 0.74 0.946666667 0.355331253 Up 0.223269021 Sbsn suprabasin "K12841|1|7e-16|88.6|nvi:100116536|calcium homeostasis endoplasmic reticulum protein;K09228|3|5e-14|82.4|sko:102807477|KRAB domain-containing zinc finger protein;K14713|5|2e-13|80.9|pss:102454955|solute carrier family 39 (zinc transporter), member 7" GO:0044424;GO:0044424 - - "gi|148692041|gb|EDL23988.1|/1.8722e-69/suprabasin, partial [Mus musculus]" 242202 6728 0.95 0.74 -0.360402243 Down 0.223269021 Pde5a "phosphodiesterase 5A, cGMP-specific" "K13762|1|0.0|1746|mmu:242202|cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35]" - - - - 75547 12543 7.883333333 8.526666667 0.113176081 Up 0.223250216 Akap13 A kinase (PRKA) anchor protein 13 K16529|1|0.0|4870|mmu:75547|A-kinase anchor protein 13 GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0017016//Ras GTPase binding;GO:0008289//lipid binding GO:0003300//cardiac muscle hypertrophy;GO:0001932//regulation of protein phosphorylation;GO:0006913//nucleocytoplasmic transport;GO:0009966//regulation of signal transduction;GO:0033036;GO:0007266//Rho protein signal transduction gi|189181672|ref|NP_083608.1|/0/A-kinase anchor protein 13 [Mus musculus] 69002 3035 0.286666667 0.45 0.650550842 Up 0.223240814 1500026H17Rik RIKEN cDNA 1500026H17 gene K10601|1|1e-07|62.0|gga:100859884|E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27] - - - - 16669 1396 0.433333333 0.276666667 -0.647328382 Down 0.223240814 Krt19 keratin 19 "K07604|1|1e-177|625|mmu:16669|type I keratin, acidic" - - - - 21956 1199.13 7926.546667 8332 0.071970371 Up 0.223212607 Tnnt2 "troponin T2, cardiac" "K12045|1|1e-99|365|mmu:21956|troponin T, cardiac muscle" GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding GO:0006941//striated muscle contraction;GO:0043462//regulation of ATPase activity;GO:0032971//regulation of muscle filament sliding;GO:0003208//cardiac ventricle morphogenesis;GO:0030239//myofibril assembly;GO:0003209//cardiac atrium morphogenesis;GO:0051259//protein oligomerization;GO:0007015//actin filament organization;GO:0010038//response to metal ion;GO:0009154//purine ribonucleotide catabolic process;GO:0006941//striated muscle contraction;GO:0043462//regulation of ATPase activity;GO:0032971//regulation of muscle filament sliding;GO:0003208//cardiac ventricle morphogenesis;GO:0030239//myofibril assembly;GO:0003209//cardiac atrium morphogenesis;GO:0051259//protein oligomerization;GO:0007015//actin filament organization;GO:0010038//response to metal ion;GO:0009154//purine ribonucleotide catabolic process;GO:0006941//striated muscle contraction;GO:0043462//regulation of ATPase activity;GO:0032971//regulation of muscle filament sliding;GO:0003208//cardiac ventricle morphogenesis;GO:0030239//myofibril assembly;GO:0003209//cardiac atrium morphogenesis;GO:0051259//protein oligomerization;GO:0007015//actin filament organization;GO:0010038//response to metal ion;GO:0009154//purine ribonucleotide catabolic process;GO:0006941//striated muscle contraction;GO:0043462//regulation of ATPase activity;GO:0032971//regulation of muscle filament sliding;GO:0003208//cardiac ventricle morphogenesis;GO:0030239//myofibril assembly;GO:0003209//cardiac atrium morphogenesis;GO:0051259//protein oligomerization;GO:0007015//actin filament organization;GO:0010038//response to metal ion;GO:0009154//purine ribonucleotide catabolic process;GO:0006941//striated muscle contraction;GO:0043462//regulation of ATPase activity;GO:0032971//regulation of muscle filament sliding;GO:0003208//cardiac ventricle morphogenesis;GO:0030239//myofibril assembly;GO:0003209//cardiac atrium morphogenesis;GO:0051259//protein oligomerization;GO:0007015//actin filament organization;GO:0010038//response to metal ion;GO:0009154//purine ribonucleotide catabolic process;GO:0006941//striated muscle contraction;GO:0043462//regulation of ATPase activity;GO:0032971//regulation of muscle filament sliding;GO:0003208//cardiac ventricle morphogenesis;GO:0030239//myofibril assembly;GO:0003209//cardiac atrium morphogenesis;GO:0051259//protein oligomerization;GO:0007015//actin filament organization;GO:0010038//response to metal ion;GO:0009154//purine ribonucleotide catabolic process;GO:0006941//striated muscle contraction;GO:0043462//regulation of ATPase activity;GO:0032971//regulation of muscle filament sliding;GO:0003208//cardiac ventricle morphogenesis;GO:0030239//myofibril assembly;GO:0003209//cardiac atrium morphogenesis;GO:0051259//protein oligomerization;GO:0007015//actin filament organization;GO:0010038//response to metal ion;GO:0009154//purine ribonucleotide catabolic process;GO:0006941//striated muscle contraction;GO:0043462//regulation of ATPase activity;GO:0032971//regulation of muscle filament sliding;GO:0003208//cardiac ventricle morphogenesis;GO:0030239//myofibril assembly;GO:0003209//cardiac atrium morphogenesis;GO:0051259//protein oligomerization;GO:0007015//actin filament organization;GO:0010038//response to metal ion;GO:0009154//purine ribonucleotide catabolic process;GO:0006941//striated muscle contraction;GO:0043462//regulation of ATPase activity;GO:0032971//regulation of muscle filament sliding;GO:0003208//cardiac ventricle morphogenesis;GO:0030239//myofibril assembly;GO:0003209//cardiac atrium morphogenesis;GO:0051259//protein oligomerization;GO:0007015//actin filament organization;GO:0010038//response to metal ion;GO:0009154//purine ribonucleotide catabolic process "gi|148707615|gb|EDL39562.1|/3.70771e-97/troponin T2, cardiac, isoform CRA_a, partial [Mus musculus]" 333670 1228 0.243333333 0.116666667 -1.060541542 Down 0.223090376 Gm867 predicted gene 867 - - - - gi|568967875|ref|XP_006513861.1|/4.32069e-69/PREDICTED: uncharacterized protein C22orf15 homolog isoform X1 [Mus musculus] 23894 1707 5.63 5.146666667 -0.129496576 Down 0.223071571 Gtf2h2 "general transcription factor II H, polypeptide 2" K03142|1|0.0|776|mmu:23894|transcription initiation factor TFIIH subunit 2 GO:0005667//transcription factor complex "GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0042623//ATPase activity, coupled" "GO:0006351//transcription, DNA-templated;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0006464//cellular protein modification process;GO:0006281//DNA repair" gi|225543398|ref|NP_071294.3|/0/general transcription factor IIH subunit 2 [Mus musculus] 69228 3651 5.276666667 5.756666667 0.125606827 Up 0.223071571 Zfp746 zinc finger protein 746 K09228|1|0.0|1073|mmu:69228|KRAB domain-containing zinc finger protein - - - gi|74221014|dbj|BAE33667.1|/0/unnamed protein product [Mus musculus] 668253 1708 2.846666667 3.21 0.173299728 Up 0.223071571 Dleu2 "deleted in lymphocytic leukemia, 2" - - - - - 192193 5858 2.2 1.903333333 -0.208975279 Down 0.223062169 Edem1 "ER degradation enhancer, mannosidase alpha-like 1" "K10084|1|0.0|1205|mmu:192193|ER degradation enhancer, mannosidase alpha-like 1" GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0005515//protein binding;GO:0015924//mannosyl-oligosaccharide mannosidase activity;GO:0046872//metal ion binding GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006487//protein N-linked glycosylation;GO:0030968//endoplasmic reticulum unfolded protein response gi|37359844|dbj|BAC97900.1|/0/mKIAA0212 protein [Mus musculus] 13346 3065 1347.783333 1413.936667 0.069128909 Up 0.222996352 Des desmin K07610|1|0.0|708|mmu:13346|desmin GO:0005886//plasma membrane;GO:0005913//cell-cell adherens junction;GO:0005882//intermediate filament;GO:0045202//synapse;GO:0031674//I band GO:0005515//protein binding;GO:0005198//structural molecule activity GO:0048513//animal organ development "gi|148667985|gb|EDL00402.1|/0/desmin, partial [Mus musculus]" 78076 653 0.09 0.01 -3.169925001 Down 0.22294934 Lcn8 lipocalin 8 - - - GO:0009719;GO:0051234//establishment of localization gi|14994308|ref|NP_149157.1|/3.18891e-95/epididymal-specific lipocalin-8 precursor [Mus musculus] 66104 1144 0.09 0.01 -3.169925001 Down 0.22294934 Tceal6 transcription elongation factor A (SII)-like 6 - - "GO:0008135//translation factor activity, RNA binding" "GO:0006351//transcription, DNA-templated;GO:0006412//translation" "gi|148691879|gb|EDL23826.1|/8.58853e-77/mCG114170, isoform CRA_a, partial [Mus musculus]" 75772 1694 0.093333333 0.01 -3.222392421 Down 0.22294934 Pnpla5 patatin-like phospholipase domain containing 5 K16814|1|0.0|895|mmu:75772|patatin-like phospholipase domain-containing protein 5 [EC:3.1.1.-] - GO:0003824//catalytic activity GO:0006629//lipid metabolic process gi|115749409|ref|NP_083703.1|/0/patatin-like phospholipase domain-containing protein 5 [Mus musculus] 77857 1082 0.01 0.093333333 3.222392421 Up 0.22294934 9430065F17Rik RIKEN cDNA 9430065F17 gene - - - - - 76747 589 0.093333333 0.01 -3.222392421 Down 0.22294934 Dapl1 death associated protein-like 1 - - - GO:0012501//programmed cell death;GO:0048869//cellular developmental process gi|62988342|ref|NP_083999.1|/4.60609e-54/death-associated protein-like 1 [Mus musculus] 80893 2070 0.01 0.09 3.169925001 Up 0.22294934 Tmprss5 "transmembrane protease, serine 5 (spinesin)" K09636|1|0.0|898|mmu:80893|transmembrane protease serine 5 [EC:3.4.21.-] GO:0044297//cell body;GO:0031224//intrinsic component of membrane GO:0038024//cargo receptor activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process "gi|148693772|gb|EDL25719.1|/0/transmembrane protease, serine 5 (spinesin), isoform CRA_a, partial [Mus musculus]" 75124 1163 0.09 0.01 -3.169925001 Down 0.22294934 Nxnl2 nucleoredoxin-like 2 K17609|1|9e-85|316|mmu:75124|nucleoredoxin [EC:1.8.1.8] - - - gi|568982572|ref|XP_006517022.1|/4.79849e-99/PREDICTED: nucleoredoxin-like protein 2 isoform X2 [Mus musculus] 100504234 2151 0.093333333 0.01 -3.222392421 Down 0.22294934 Ccdc170 coiled-coil domain containing 170 K20478|1|4e-24|115|dre:557772|golgin subfamily B member 1 - - - gi|307548930|ref|NP_001182601.1|/0/coiled-coil domain-containing protein 170 [Mus musculus] 329159 1906 0.01 0.093333333 3.222392421 Up 0.22294934 9130227L01Rik RIKEN cDNA 9130227L01 gene - - - - "gi|148667621|gb|EDL00038.1|/1.64179e-34/mCG145723, isoform CRA_a [Mus musculus]" 73183 940 0.063333333 0.186666667 1.559427409 Up 0.22294934 5430402O13Rik RIKEN cDNA 5430402O13 gene - - - - - 72316 566 0.01 0.093333333 3.222392421 Up 0.22294934 2310008N11Rik RIKEN cDNA 2310008N11 gene - - - - - 667794 570 0.01 0.093333333 3.222392421 Up 0.22294934 Gm8817 predicted gene 8817 - - - - gi|197385320|ref|NP_001095076.1|/3.24618e-54/uncharacterized protein LOC667794 [Mus musculus] 259108 1038 0.01 0.09 3.169925001 Up 0.22294934 Olfr550 olfactory receptor 550 K04257|1|5e-166|585|mmu:259108|olfactory receptor GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007608//sensory perception of smell gi|568950725|ref|XP_006507941.1|/1.14839e-170/PREDICTED: olfactory receptor 550 isoform X1 [Mus musculus] 474145 1107 0.01 0.09 3.169925001 Up 0.22294934 Clec4a4 "C-type lectin domain family 4, member a4" K10057|1|1e-132|474|mmu:474145|C-type lectin domain family 4 member A - GO:0005488//binding - "gi|54312070|ref|NP_001005860.1|/1.16671e-131/C-type lectin domain family 4, member a4 [Mus musculus]" 73333 2110 0.19 0.066666667 -1.510961919 Down 0.22294934 Slc25a31 "solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31" "K05863|1|1e-165|585|mmu:73333|solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763 gi|254692892|ref|NP_848473.2|/1.13187e-164/ADP/ATP translocase 4 [Mus musculus] 75630 610 0.09 0.01 -3.169925001 Down 0.22294934 1700020G17Rik RIKEN cDNA 1700020G17 gene - - - - "gi|148689769|gb|EDL21716.1|/7.61033e-18/mCG145346, partial [Mus musculus]" 100038659 971 0.01 0.093333333 3.222392421 Up 0.22294934 Mirt2 myocardial infraction associated transcript 2 K01469|1|4e-09|64.7|mcf:102141374|5-oxoprolinase (ATP-hydrolysing) [EC:3.5.2.9] GO:0005815//microtubule organizing center GO:0015631//tubulin binding - gi|74206984|dbj|BAE33286.1|/1.34425e-37/unnamed protein product [Mus musculus] 68400 618 0.09 0.01 -3.169925001 Down 0.22294934 0610043K17Rik RIKEN cDNA 0610043K17 gene - - - - "gi|148698925|gb|EDL30872.1|/2.52829e-56/mCG144801, partial [Mus musculus]" 68233 572 0.01 0.093333333 3.222392421 Up 0.22294934 Fam229a "family with sequence similarity 229, member A" - - - - gi|157824220|ref|NP_001102736.1|/4.31534e-54/protein FAM229A [Rattus norvegicus] 435376 1176 0.09 0.01 -3.169925001 Down 0.22294934 Atp6ap1l "ATPase, H+ transporting, lysosomal accessory protein 1-like" K03662|1|3e-23|112|lcm:102350146|V-type H+-transporting ATPase S1 subunit - - - gi|758178154|gb|AJO60877.1|/1.60401e-150/Ac45-related protein [Mus musculus] 100041774 993 0.01 0.093333333 3.222392421 Up 0.22294934 Gm10413 predicted gene 10413 "K03844|1|2e-21|105|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - gi|270132340|ref|NP_083564.2|/1.91819e-111/uncharacterized protein LOC100041774 [Mus musculus] 237880 1038 0.01 0.09 3.169925001 Up 0.22294934 1700071K01Rik RIKEN cDNA 1700071K01 gene K17080|1|5e-126|452|mmu:237880|prohibitin 1 GO:0031981//nuclear lumen;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane "GO:0000975//regulatory region DNA binding;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0019899//enzyme binding" "GO:0006476//protein deacetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0008585//female gonad development;GO:0030521//androgen receptor signaling pathway;GO:0006915//apoptotic process;GO:0006259//DNA metabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0033144//negative regulation of intracellular steroid hormone receptor signaling pathway;GO:0009887//organ morphogenesis;GO:0097305//response to alcohol;GO:0070741//response to interleukin-6;GO:0016049//cell growth;GO:0009725//response to hormone" gi|85702063|ref|NP_001028937.1|/4.29713e-125/prohibitin-like [Mus musculus] 75115 1191 0.01 0.09 3.169925001 Up 0.22294934 4930509E16Rik RIKEN cDNA 4930509E16 gene - - - - - 57264 607 0.09 0.01 -3.169925001 Down 0.22294934 Retn resistin K13438|1|3e-52|207|mmu:57264|resistin GO:0043231//intracellular membrane-bounded organelle;GO:0044421;GO:0043231//intracellular membrane-bounded organelle;GO:0044421 GO:0005102//receptor binding;GO:0005102//receptor binding GO:0009605//response to external stimulus;GO:0014909//smooth muscle cell migration;GO:0032370//positive regulation of lipid transport;GO:0010604;GO:0043434//response to peptide hormone;GO:0008284//positive regulation of cell proliferation;GO:0007268//chemical synaptic transmission;GO:0030154//cell differentiation;GO:0044767//single-organism developmental process;GO:0007631//feeding behavior;GO:0009605//response to external stimulus;GO:0014909//smooth muscle cell migration;GO:0032370//positive regulation of lipid transport;GO:0010604;GO:0043434//response to peptide hormone;GO:0008284//positive regulation of cell proliferation;GO:0007268//chemical synaptic transmission;GO:0030154//cell differentiation;GO:0044767//single-organism developmental process;GO:0007631//feeding behavior gi|12667798|ref|NP_075360.1|/2.75865e-51/resistin precursor [Mus musculus] 70192 1088 0.093333333 0.01 -3.222392421 Down 0.22294934 Cd209g CD209g antigen K06563|1|2e-113|411|mmu:69142|CD209 antigen - GO:0005488//binding - gi|568953502|ref|XP_006508948.1|/2.7847e-130/PREDICTED: CD209g antigen isoform X1 [Mus musculus] 20208 607 0.01 0.09 3.169925001 Up 0.22294934 Saa1 serum amyloid A 1 K17310|1|1e-62|241|mmu:20208|serum amyloid A protein GO:0034358//plasma lipoprotein particle GO:0005488//binding GO:0002526//acute inflammatory response;GO:0050663//cytokine secretion;GO:0016125//sterol metabolic process;GO:0007155//cell adhesion;GO:0030595//leukocyte chemotaxis;GO:0051480//regulation of cytosolic calcium ion concentration "gi|148690992|gb|EDL22939.1|/2.25974e-62/mCG144019, partial [Mus musculus]" 384244 651 0.09 0.01 -3.169925001 Down 0.22294934 Gm5294 predicted gene 5294 K09405|1|1e-33|144|ssc:100511634|forkhead box protein L - - - gi|304376263|ref|NP_001182057.1|/2.59061e-121/forkhead box L1-like [Mus musculus] 218454 4348 0.45 0.633333333 0.493040011 Up 0.222939938 Lhfpl2 lipoma HMGIC fusion partner-like 2 - GO:0031224//intrinsic component of membrane - - gi|27369844|ref|NP_766177.1|/1.03611e-112/lipoma HMGIC fusion partner-like 2 protein [Mus musculus] 12449 3099 0.366666667 0.54 0.558490289 Up 0.222930535 Ccnf cyclin F K10289|1|0.0|1432|mmu:12449|F-box protein 1 (cyclin F) GO:0043231//intracellular membrane-bounded organelle;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0005813//centrosome - GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010639;GO:0032446//protein modification by small protein conjugation;GO:0000087//mitotic M phase;GO:0044767//single-organism developmental process gi|568998797|ref|XP_006523617.1|/0/PREDICTED: cyclin-F isoform X1 [Mus musculus] 14706 2912 0.12 0.023333333 -2.362570079 Down 0.22291173 Gng4 "guanine nucleotide binding protein (G protein), gamma 4" K04541|1|1e-34|151|rno:114118|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane GO:0060089;GO:0005488//binding;GO:0060089;GO:0005488//binding GO:0007186//G-protein coupled receptor signaling pathway;GO:0015980//energy derivation by oxidation of organic compounds;GO:0007267//cell-cell signaling;GO:0033762//response to glucagon;GO:0016049//cell growth;GO:0007186//G-protein coupled receptor signaling pathway;GO:0015980//energy derivation by oxidation of organic compounds;GO:0007267//cell-cell signaling;GO:0033762//response to glucagon;GO:0016049//cell growth gi|676280368|gb|KFO34249.1|/1.9443e-34/Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 [Fukomys damarensis] 16197 3227 0.023333333 0.12 2.362570079 Up 0.22291173 Il7r interleukin 7 receptor K05072|1|0.0|833|mmu:16197|interleukin 7 receptor GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0004896//cytokine receptor activity;GO:0005488//binding GO:0042592//homeostatic process;GO:0010467//gene expression;GO:0040007//growth;GO:0006310//DNA recombination;GO:0001911;GO:0032535//regulation of cellular component size;GO:0019221//cytokine-mediated signaling pathway;GO:0002440;GO:0033077//T cell differentiation in thymus;GO:0042113//B cell activation gi|45269152|ref|NP_032398.3|/0/interleukin-7 receptor subunit alpha precursor [Mus musculus] 432939 2882 0.023333333 0.12 2.362570079 Up 0.22291173 Gm5468 predicted gene 5468 - - - - - 76854 2525 1.1 1.336666667 0.281136212 Up 0.222892926 Gper1 G protein-coupled estrogen receptor 1 K04246|1|0.0|726|mmu:76854|G protein-coupled receptor 30 GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0004888//transmembrane signaling receptor activity;GO:0008289//lipid binding GO:0030522//intracellular receptor signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0009755//hormone-mediated signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway gi|254588034|ref|NP_084047.2|/0/G-protein coupled estrogen receptor 1 [Mus musculus] 67530 503 1031.756667 984.0566667 -0.06828946 Down 0.222845914 Uqcrb ubiquinol-cytochrome c reductase binding protein K00417|1|7e-53|207|mmu:67530|ubiquinol-cytochrome c reductase subunit 7 GO:0005746//mitochondrial respiratory chain GO:0005515//protein binding GO:0051234//establishment of localization;GO:0051259//protein oligomerization;GO:0022904//respiratory electron transport chain gi|13385726|ref|NP_080495.1|/4.50729e-52/cytochrome b-c1 complex subunit 7 [Mus musculus] 52535 1637 10.43 11.19 0.101470878 Up 0.222780097 Mettl17 methyltransferase like 17 K11423|1|4e-42|175|smm:Smp_133910|histone-lysine N-methyltransferase SETD2 [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0046914//transition metal ion binding;GO:0016741 GO:0010467//gene expression "gi|148710332|gb|EDL42278.1|/0/methyltransferase 11 domain containing 1, isoform CRA_b, partial [Mus musculus]" 12833 3990 31.76666667 29.98 -0.08351333 Down 0.222742487 Col6a1 "collagen, type VI, alpha 1" "K06238|1|0.0|1039|mmu:12833|collagen, type VI, alpha" GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix;GO:0032991//macromolecular complex GO:0019838//growth factor binding GO:0051291//protein heterooligomerization;GO:0043200//response to amino acid;GO:0022610 gi|6753484|ref|NP_034063.1|/0/collagen alpha-1(VI) chain precursor [Mus musculus] 21376 1583 30.03333333 31.82 0.08336923 Up 0.222742487 Tbrg1 transforming growth factor beta regulated gene 1 K09188|1|4e-13|79.0|dsi:Dsimw501_GD16408|histone-lysine N-methyltransferase MLL3 [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle - GO:0044765//single-organism transport;GO:0006259//DNA metabolic process;GO:0008283//cell proliferation;GO:0022402//cell cycle process;GO:0031647//regulation of protein stability gi|224967132|ref|NP_079565.2|/2.33948e-177/transforming growth factor beta regulator 1 [Mus musculus] 72056 1882 6.04 6.576666667 0.122808001 Up 0.222695476 1810055G02Rik RIKEN cDNA 1810055G02 gene K10955|1|8e-13|78.2|cfr:102518704|intestinal mucin-2 GO:0031224//intrinsic component of membrane - - "gi|148701003|gb|EDL32950.1|/0/RIKEN cDNA 1810055G02, isoform CRA_a, partial [Mus musculus]" 70392 1260 6.93 6.386666667 -0.117792197 Down 0.222695476 Asb12 ankyrin repeat and SOCS box-containing 12 K10334|1|9e-170|598|mmu:70392|ankyrin repeat and SOCS box protein 12 - - GO:0007165//signal transduction;GO:0007165//signal transduction gi|20270029|ref|NP_543134.1|/6.45997e-169/ankyrin repeat and SOCS box protein 12 [Mus musculus] 100503652 1454 6.063333333 6.6 0.122354887 Up 0.222695476 Gm16845 "predicted gene, 16845" K04405|1|2e-12|76.3|tup:102478524|evolutionarily conserved signaling intermediate in Toll pathway - - - - 74211 4934 6.71 6.17 -0.121042277 Down 0.222695476 1700017B05Rik RIKEN cDNA 1700017B05 gene K06491|1|2e-07|61.6|mze:101485754|neural cell adhesion molecule - - - gi|110625983|ref|NP_083096.1|/0/uncharacterized protein C15orf39 homolog [Mus musculus] 99730 1289 6.376666667 6.92 0.11796957 Up 0.222695476 Taf13 TATA-box binding protein associated factor 13 K03127|1|7e-49|197|lcm:102362267|transcription initiation factor TFIID subunit 13 - - - gi|149708828|ref|XP_001493887.1|/5.86895e-48/PREDICTED: transcription initiation factor TFIID subunit 13 [Equus caballus] 108954 5588 6.583333333 6.046666667 -0.122678197 Down 0.222695476 Ppp1r15b "protein phosphatase 1, regulatory (inhibitor) subunit 15b" K17558|1|0.0|1267|mmu:108954|protein phosphatase 1 regulatory subunit 15B - GO:0004721//phosphoprotein phosphatase activity GO:0006413//translational initiation;GO:0006984//ER-nucleus signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0000302//response to reactive oxygen species gi|27597067|ref|NP_598580.1|/0/protein phosphatase 1 regulatory subunit 15B [Mus musculus] 11777 1524.72 8.643333333 8.016666667 -0.108585312 Down 0.222582647 Ap3s1 "adaptor-related protein complex 3, sigma 1 subunit" K12399|1|6e-103|313|pon:100440806|AP-3 complex subunit sigma - - - - 56321 1844 7.71 8.343333333 0.113893025 Up 0.222582647 Aatf apoptosis antagonizing transcription factor K14782|1|0.0|721|mmu:56321|protein AATF/BFR2 GO:0031981//nuclear lumen;GO:0005815//microtubule organizing center;GO:0005924//cell-substrate adherens junction GO:0030275//LRR domain binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0008092//cytoskeletal protein binding GO:0000278//mitotic cell cycle;GO:0006366//transcription from RNA polymerase II promoter;GO:0022613//ribonucleoprotein complex biogenesis;GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0022610;GO:0010561;GO:0009790//embryo development;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0033554//cellular response to stress gi|74194197|dbj|BAE24653.1|/0/unnamed protein product [Mus musculus] 216350 1380 0.183333333 0.066666667 -1.459431619 Down 0.222545037 Tspan8 tetraspanin 8 K17349|1|3e-116|421|mmu:216350|tetraspanin-8 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0007596//blood coagulation;GO:0007596//blood coagulation;GO:0007596//blood coagulation gi|22122475|ref|NP_666122.1|/2.7467e-115/tetraspanin-8 [Mus musculus] 16509 3155 1.256666667 1.023333333 -0.296325868 Down 0.222535635 Kcne1 "potassium voltage-gated channel, Isk-related subfamily, member 1" K04894|1|5e-67|259|mmu:16509|potassium voltage-gated channel Isk-related subfamily E member 1 GO:0005604//basement membrane;GO:0000323//lytic vacuole;GO:0031674//I band;GO:0005887//integral component of plasma membrane GO:0008092//cytoskeletal protein binding;GO:0016247//channel regulator activity;GO:0005249//voltage-gated potassium channel activity GO:0002027//regulation of heart rate;GO:0071805//potassium ion transmembrane transport;GO:0006486//protein glycosylation;GO:0034767//positive regulation of ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0002064//epithelial cell development gi|6680528|ref|NP_032450.1|/3.89053e-66/potassium voltage-gated channel subfamily E member 1 [Mus musculus] 11555 2269 1 1.23 0.298658316 Up 0.222535635 Adrb2 "adrenergic receptor, beta 2" K04142|1|0.0|855|mmu:11555|adrenergic receptor beta-2 - - - - 14173 695 0.436666667 0.28 -0.641105579 Down 0.222526233 Fgf2 fibroblast growth factor 2 K18497|1|2e-83|310|mmu:14173|fibroblast growth factor 2 - - - - 170720 3958 0.64 0.84 0.392317423 Up 0.22251683 Card14 "caspase recruitment domain family, member 14" K07367|1|7e-52|209|mze:101473150|caspase recruitment domain-containing protein 11 GO:0044424 GO:0019904//protein domain specific binding GO:0006915//apoptotic process gi|18700028|ref|NP_570956.1|/0/caspase recruitment domain-containing protein 14 [Mus musculus] 14128 2037 0.283333333 0.146666667 -0.949959318 Down 0.222498025 Fcer2a "Fc receptor, IgE, low affinity II, alpha polypeptide" "K06468|1|3e-153|545|mmu:14128|Fc receptor, IgE, low affinity II" GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface GO:0043169//cation binding;GO:0019865//immunoglobulin binding;GO:0043169//cation binding;GO:0019865//immunoglobulin binding;GO:0043169//cation binding;GO:0019865//immunoglobulin binding;GO:0043169//cation binding;GO:0019865//immunoglobulin binding;GO:0043169//cation binding;GO:0019865//immunoglobulin binding;GO:0043169//cation binding;GO:0019865//immunoglobulin binding;GO:0043169//cation binding;GO:0019865//immunoglobulin binding GO:0032770//positive regulation of monooxygenase activity;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0031343//positive regulation of cell killing;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032770//positive regulation of monooxygenase activity;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0031343//positive regulation of cell killing;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032770//positive regulation of monooxygenase activity;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0031343//positive regulation of cell killing;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032770//positive regulation of monooxygenase activity;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0031343//positive regulation of cell killing;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032770//positive regulation of monooxygenase activity;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0031343//positive regulation of cell killing;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032770//positive regulation of monooxygenase activity;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0031343//positive regulation of cell killing;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032770//positive regulation of monooxygenase activity;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0031343//positive regulation of cell killing;GO:0010557//positive regulation of macromolecule biosynthetic process gi|359279923|ref|NP_001240675.1|/2.32669e-167/low affinity immunoglobulin epsilon Fc receptor isoform F [Mus musculus] 245050 3622 0.286666667 0.146666667 -0.966833136 Down 0.222498025 Fam198a "family with sequence similarity 198, member A" - - - - gi|123795368|sp|Q3UY90.1|F198A_MOUSE/0/RecName: Full=Protein FAM198A; Flags: Precursor 12974 2828 676.72 646.4266667 -0.066072313 Down 0.222460416 Cs citrate synthase K01647|1|0.0|917|mmu:12974|citrate synthase [EC:2.3.3.1] - - - - 67273 1222 614.7433333 585.53 -0.070241094 Down 0.222451014 Ndufa10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10 K03954|1|0.0|701|mmu:67273|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10 GO:0005746//mitochondrial respiratory chain "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0032550" GO:0006091//generation of precursor metabolites and energy;GO:0042221//response to chemical;GO:0051234//establishment of localization;GO:0006725//cellular aromatic compound metabolic process "gi|13195624|ref|NP_077159.1|/0/NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial precursor [Mus musculus]" 56175 3736 0.88 1.1 0.321928095 Up 0.222432209 Bace2 beta-site APP-cleaving enzyme 2 K07747|1|0.0|944|mmu:56175|beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:3.4.23.45] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0004175//endopeptidase activity GO:0010561;GO:0033619//membrane protein proteolysis gi|244798416|ref|NP_062390.3|/0/beta-secretase 2 precursor [Mus musculus] 328309 2187 0.89 1.113333333 0.323008361 Up 0.222432209 Gm9776 predicted gene 9776 - - - - gi|26334283|dbj|BAC30859.1|/7.61992e-55/unnamed protein product [Mus musculus] 19157 3169.75 31.37 29.61666667 -0.082976254 Down 0.222366392 Cyth1 cytohesin 1 K18441|1|0.0|813|rno:116691|cytohesin GO:0043296//apical junction complex;GO:0044424 GO:0008289//lipid binding GO:0030010//establishment of cell polarity;GO:0032011//ARF protein signal transduction gi|60360016|dbj|BAD90227.1|/0/mKIAA4240 protein [Mus musculus] 58799 4066.43 10.15 10.89666667 0.102407149 Up 0.222338185 Crbn cereblon K11793|1|0.0|878|mmu:58799|cereblon - - - - 100037282 1614 31.4 33.14 0.077809043 Up 0.222291173 Rsph3b radial spoke 3B homolog (Chlamydomonas) - - - - gi|82571474|gb|AAI10285.1|/0/Rshl2a protein [Mus musculus] 54607 3210 3.706666667 3.326666667 -0.156045067 Down 0.222253564 Socs6 suppressor of cytokine signaling 6 K04699|1|0.0|968|mmu:54607|suppressor of cytokine signaling 6/7 GO:0044459 GO:0005488//binding GO:0032446//protein modification by small protein conjugation;GO:0040007//growth;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0007165//signal transduction;GO:0042110//T cell activation gi|31543755|ref|NP_061291.2|/0/suppressor of cytokine signaling 6 [Mus musculus] 98417 3283 17.12333333 16.07 -0.091593644 Down 0.222253564 Cnih4 cornichon family AMPA receptor auxiliary protein 4 K20368|1|3e-73|279|mmu:98417|protein cornichon - - - - 66603 1590 3.743333333 4.143333333 0.146468369 Up 0.222197149 Gemin2 gem (nuclear organelle) associated protein 2 K13130|1|3e-156|554|mmu:66603|gem associated protein 2 GO:0016604//nuclear body;GO:0044444//cytoplasmic part;GO:0030529//intracellular ribonucleoprotein complex GO:0005488//binding "GO:0000398//mRNA splicing, via spliceosome" gi|153792166|ref|NP_079932.2|/2.53022e-155/gem-associated protein 2 [Mus musculus] 17978 8180 3.766666667 4.166666667 0.145605322 Up 0.222197149 Ncoa2 nuclear receptor coactivator 2 K11255|1|0.0|2608|mmu:17978|nuclear receptor coactivator 2 GO:0044456;GO:0044327//dendritic spine head;GO:0015630//microtubule cytoskeleton;GO:0044297//cell body;GO:0005783//endoplasmic reticulum GO:0060089;GO:0010861//thyroid hormone receptor activator activity;GO:0019904//protein domain specific binding;GO:0042974//retinoic acid receptor binding;GO:0003713//transcription coactivator activity;GO:0035258//steroid hormone receptor binding;GO:0019899//enzyme binding;GO:0008080//N-acetyltransferase activity GO:0006366//transcription from RNA polymerase II promoter;GO:0016570//histone modification;GO:0033145//positive regulation of intracellular steroid hormone receptor signaling pathway;GO:0045924//regulation of female receptivity;GO:0008406//gonad development;GO:0022037//metencephalon development gi|118026940|ref|NP_032704.2|/0/nuclear receptor coactivator 2 isoform a [Mus musculus] 16828 1661.28 455.5633333 479.2 0.072976274 Up 0.222187747 Ldha lactate dehydrogenase A K00016|1|0.0|640|myd:102763713|L-lactate dehydrogenase [EC:1.1.1.27] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0000166//nucleotide binding;GO:0004457//lactate dehydrogenase activity;GO:0019899//enzyme binding;GO:0004457//lactate dehydrogenase activity;GO:0019899//enzyme binding;GO:0000166//nucleotide binding GO:0006007//glucose catabolic process;GO:0046683//response to organophosphorus;GO:0006915//apoptotic process;GO:0048545//response to steroid hormone;GO:0000302//response to reactive oxygen species;GO:0007154//cell communication;GO:0032787//monocarboxylic acid metabolic process;GO:0009746;GO:0044767//single-organism developmental process;GO:0046496//nicotinamide nucleotide metabolic process;GO:0031667//response to nutrient levels;GO:0006007//glucose catabolic process;GO:0006915//apoptotic process;GO:0032787//monocarboxylic acid metabolic process;GO:0046496//nicotinamide nucleotide metabolic process;GO:0007154//cell communication gi|823425199|ref|XP_004409902.2|/1.76558e-142/PREDICTED: L-lactate dehydrogenase A chain-like isoform X1 [Odobenus rosmarus divergens] 14313 2572.03 0.156666667 0.3 0.937264245 Up 0.222187747 Fst follistatin K04661|1|0.0|695|mmu:14313|follistatin GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0060089;GO:0043168//anion binding;GO:0032403//protein complex binding;GO:0043168//anion binding;GO:0032403//protein complex binding;GO:0043168//anion binding;GO:0032403//protein complex binding GO:0030097//hemopoiesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0032277//negative regulation of gonadotropin secretion;GO:0008283//cell proliferation;GO:0042476//odontogenesis;GO:0008406//gonad development;GO:0001942//hair follicle development;GO:0019953//sexual reproduction;GO:0030154//cell differentiation;GO:0032924//activin receptor signaling pathway;GO:0030097//hemopoiesis;GO:0008283//cell proliferation;GO:0042476//odontogenesis;GO:0008406//gonad development;GO:0001942//hair follicle development;GO:0019953//sexual reproduction;GO:0030154//cell differentiation;GO:0032924//activin receptor signaling pathway;GO:0030097//hemopoiesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0032277//negative regulation of gonadotropin secretion;GO:0008283//cell proliferation;GO:0042476//odontogenesis;GO:0008406//gonad development;GO:0001942//hair follicle development;GO:0019953//sexual reproduction;GO:0030154//cell differentiation;GO:0032924//activin receptor signaling pathway gi|6679867|ref|NP_032072.1|/0/follistatin isoform 2 precursor [Mus musculus] 67003 1882 493.54 471.4366667 -0.066103045 Down 0.222112528 Uqcrc2 ubiquinol cytochrome c reductase core protein 2 K00415|1|0.0|803|mmu:67003|ubiquinol-cytochrome c reductase core subunit 2 GO:0005746//mitochondrial respiratory chain GO:0004175//endopeptidase activity;GO:0043169//cation binding;GO:0005515//protein binding GO:0051234//establishment of localization;GO:0019538//protein metabolic process;GO:0006091//generation of precursor metabolites and energy "gi|22267442|ref|NP_080175.1|/0/cytochrome b-c1 complex subunit 2, mitochondrial precursor [Mus musculus]" 230514 1827 16.92333333 17.96 0.085773591 Up 0.221971492 Leprot leptin receptor overlapping transcript K05062|1|2e-08|63.5|phd:102316341|leptin receptor GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding GO:0009968//negative regulation of signal transduction;GO:0007259//JAK-STAT cascade "gi|148698920|gb|EDL30867.1|/2.91709e-73/mCG146281, isoform CRA_a, partial [Mus musculus]" 13052 5151.01 4.166666667 4.593333333 0.140647793 Up 0.221905675 Cxadr coxsackie virus and adenovirus receptor K06788|1|0.0|667|rno:89843|coxsackievirus and adenovirus receptor GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0044291//cell-cell contact zone;GO:0070161;GO:0043296//apical junction complex;GO:0030141//secretory granule;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0044459;GO:0045202//synapse;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0044291//cell-cell contact zone;GO:0070161;GO:0043296//apical junction complex;GO:0030141//secretory granule;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0044459;GO:0045202//synapse;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0044291//cell-cell contact zone;GO:0070161;GO:0043296//apical junction complex;GO:0030141//secretory granule;GO:0016021//integral component of membrane;GO:0044421;GO:0044459;GO:0045202//synapse GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding GO:0034330;GO:0016337//single organismal cell-cell adhesion;GO:0008285//negative regulation of cell proliferation;GO:0030036//actin cytoskeleton organization;GO:0048738//cardiac muscle tissue development;GO:0002252;GO:0086065//cell communication involved in cardiac conduction;GO:0044765//single-organism transport;GO:0007276//gamete generation;GO:0030595//leukocyte chemotaxis;GO:0001894//tissue homeostasis;GO:0034330;GO:0016337//single organismal cell-cell adhesion;GO:0008285//negative regulation of cell proliferation;GO:0030036//actin cytoskeleton organization;GO:0048738//cardiac muscle tissue development;GO:0002252;GO:0086065//cell communication involved in cardiac conduction;GO:0044765//single-organism transport;GO:0007276//gamete generation;GO:0030595//leukocyte chemotaxis;GO:0001894//tissue homeostasis;GO:0007599//hemostasis;GO:0034330;GO:0016337//single organismal cell-cell adhesion;GO:0008285//negative regulation of cell proliferation;GO:0030036//actin cytoskeleton organization;GO:0048738//cardiac muscle tissue development;GO:0002252;GO:0086065//cell communication involved in cardiac conduction;GO:0044765//single-organism transport;GO:0007276//gamete generation;GO:0002682//regulation of immune system process;GO:0030595//leukocyte chemotaxis;GO:0001894//tissue homeostasis gi|6857775|ref|NP_034118.1|/0/coxsackievirus and adenovirus receptor homolog isoform b precursor [Mus musculus] 381802 1802 4.236666667 4.67 0.140492925 Up 0.221905675 Tsen2 tRNA splicing endonuclease subunit 2 K15322|1|0.0|862|mmu:381802|tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9] GO:0005815//microtubule organizing center;GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0004518//nuclease activity;GO:0097159//organic cyclic compound binding "GO:0006399//tRNA metabolic process;GO:0000394//RNA splicing, via endonucleolytic cleavage and ligation" "gi|148667113|gb|EDK99529.1|/0/tRNA splicing endonuclease 2 homolog (SEN2, S. cerevisiae), isoform CRA_c, partial [Mus musculus]" 212032 2894 0.463333333 0.3 -0.627087976 Down 0.221886871 Hk3 hexokinase 3 K00844|1|0.0|1743|mmu:212032|hexokinase [EC:2.7.1.1] - - - gi|84370288|ref|NP_001028417.1|/0/hexokinase-3 isoform 1 [Mus musculus] 21406 4707 5.473333333 5.003333333 -0.12953015 Down 0.221877468 Tcf12 transcription factor 12 K15603|1|0.0|1282|mmu:21406|transcription factor 4/12 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0044212//transcription regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0044212//transcription regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0044212//transcription regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter gi|359718981|ref|NP_001240793.1|/0/transcription factor 12 isoform 4 [Mus musculus] 13433 5269.94 5.6 5.13 -0.126468001 Down 0.221877468 Dnmt1 DNA methyltransferase (cytosine-5) 1 K00558|1|0.0|2932|mmu:13433|DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] "GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region" GO:0046914//transition metal ion binding;GO:0000166//nucleotide binding;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0019899//enzyme binding;GO:0046914//transition metal ion binding;GO:0000166//nucleotide binding;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0019899//enzyme binding;GO:0046914//transition metal ion binding;GO:0000166//nucleotide binding;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0019899//enzyme binding;GO:0046914//transition metal ion binding;GO:0000166//nucleotide binding;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0019899//enzyme binding "GO:0006351//transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0008283//cell proliferation;GO:0031062//positive regulation of histone methylation;GO:0032776//DNA methylation on cytosine;GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0031061//negative regulation of histone methylation;GO:0006351//transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0008283//cell proliferation;GO:0031062//positive regulation of histone methylation;GO:0032776//DNA methylation on cytosine;GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0031061//negative regulation of histone methylation;GO:0006351//transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0008283//cell proliferation;GO:0031062//positive regulation of histone methylation;GO:0032776//DNA methylation on cytosine;GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0031061//negative regulation of histone methylation;GO:0006351//transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0008283//cell proliferation;GO:0031062//positive regulation of histone methylation;GO:0032776//DNA methylation on cytosine;GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0031061//negative regulation of histone methylation" "gi|148693196|gb|EDL25143.1|/0/DNA methyltransferase (cytosine-5) 1, isoform CRA_e, partial [Mus musculus]" 102640359 557 8.08 8.703333333 0.107212759 Up 0.221849261 LOC102640359 uncharacterized LOC102640359 - - - - - 69008 3037 8.456666667 7.836666667 -0.10984898 Down 0.221849261 Cab39l calcium binding protein 39-like K08272|1|0.0|663|mmu:69008|calcium binding protein 39 GO:0044444//cytoplasmic part - GO:0022402//cell cycle process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0019217//regulation of fatty acid metabolic process gi|795260203|ref|XP_011919654.1|/0/PREDICTED: calcium-binding protein 39-like isoform X1 [Cercocebus atys] 14854 1978 8.056666667 8.673333333 0.106403489 Up 0.221849261 Gss glutathione synthetase K01920|1|0.0|905|mmu:14854|glutathione synthase [EC:6.3.2.3] - GO:0032550;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0016881//acid-amino acid ligase activity;GO:0033218//amide binding;GO:0072341//modified amino acid binding;GO:0032550;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0016881//acid-amino acid ligase activity;GO:0033218//amide binding;GO:0072341//modified amino acid binding GO:0010038//response to metal ion;GO:0001101//response to acid chemical;GO:0006749//glutathione metabolic process;GO:0044767//single-organism developmental process;GO:0009991//response to extracellular stimulus;GO:0034097//response to cytokine;GO:0010038//response to metal ion;GO:0001101//response to acid chemical;GO:0006749//glutathione metabolic process;GO:0044767//single-organism developmental process;GO:0009991//response to extracellular stimulus;GO:0034097//response to cytokine "gi|148674183|gb|EDL06130.1|/0/glutathione synthetase, isoform CRA_b, partial [Mus musculus]" 74410 3191 0.95 0.743333333 -0.353918209 Down 0.221839859 Ttll11 "tubulin tyrosine ligase-like family, member 11" K16604|1|0.0|1313|mmu:74410|tubulin polyglutamylase TTLL11 [EC:6.-.-.-] GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle GO:0016881//acid-amino acid ligase activity GO:0007017//microtubule-based process;GO:0018200//peptidyl-glutamic acid modification gi|212720821|ref|NP_084050.1|/0/tubulin polyglutamylase TTLL11 [Mus musculus] 20665 2713 0.763333333 0.97 0.345671555 Up 0.221839859 Sox10 SRY (sex determining region Y)-box 10 K09270|1|0.0|782|mmu:20665|transcription factor SOX7/8/10/18 (SOX group E/F) GO:0005741//mitochondrial outer membrane "GO:0005515//protein binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding" GO:0009653//anatomical structure morphogenesis;GO:0007417//central nervous system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0001667//ameboidal-type cell migration;GO:0007405//neuroblast proliferation;GO:0006915//apoptotic process;GO:0043009//chordate embryonic development;GO:0021700//developmental maturation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0050931//pigment cell differentiation;GO:0048483//autonomic nervous system development;GO:0014013//regulation of gliogenesis gi|2826523|gb|AAB99738.1|/0/putative transcription factor [Mus musculus] 66125 750 28.78333333 30.47666667 0.082471442 Up 0.221783444 Sf3b5 "splicing factor 3b, subunit 5" K12832|1|4e-46|186|cge:100756721|splicing factor 3B subunit 5 GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen - GO:0000377 gi|85540445|ref|NP_780311.2|/3.15887e-45/splicing factor 3B subunit 5 [Mus musculus] 101100 2527.42 0.363333333 0.53 0.544698631 Up 0.221755237 Ttll3 "tubulin tyrosine ligase-like family, member 3" K16608|1|0.0|1781|mmu:101100|tubulin monoglycylase TTLL3/8 [EC:6.3.2.-] GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton GO:0070735//protein-glycine ligase activity;GO:0070735//protein-glycine ligase activity GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process gi|218505698|ref|NP_001136204.1|/3.59e-137/tubulin monoglycylase TTLL3 isoform 2 [Mus musculus] 11624 4572 0.566666667 0.756666667 0.417157551 Up 0.221755237 Ahrr aryl-hydrocarbon receptor repressor K09094|1|0.0|1377|mmu:11624|aryl hydrocarbon receptor repressor - - - - 240427 9981 0.556666667 0.743333333 0.417195607 Up 0.221755237 Setbp1 SET binding protein 1 K06101|1|5e-104|383|lve:103087473|histone-lysine N-methyltransferase ASH1L [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding - gi|197927410|ref|NP_444329.2|/0/SET-binding protein [Mus musculus] 66129 972 16.75333333 17.78333333 0.0860776 Up 0.22172703 Aaed1 AhpC/TSA antioxidant enzyme domain containing 1 K15717|1|1e-08|63.2|lcm:102361632|prostamide/prostaglandin F2alpha synthase [EC:1.11.1.20] - - - gi|13384744|ref|NP_079646.1|/3.58512e-107/thioredoxin-like protein AAED1 [Mus musculus] 13043 3191.48 17.79333333 16.76666667 -0.085740905 Down 0.22172703 Cttn cortactin K06106|1|0.0|1030|mmu:13043|cortactin GO:0044444//cytoplasmic part;GO:0031252//cell leading edge;GO:0043232;GO:0043232;GO:0031252//cell leading edge;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0005515//protein binding GO:0006897//endocytosis;GO:0007417//central nervous system development;GO:0006897//endocytosis gi|357588432|ref|NP_001239501.1|/0/src substrate cortactin isoform 2 [Mus musculus] 12577 1932.87 17.06666667 16.03333333 -0.090106916 Down 0.22172703 Cdkn1c cyclin-dependent kinase inhibitor 1C (P57) K09993|1|3e-144|514|mmu:12577|cyclin-dependent kinase inhibitor 1C GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0019887//protein kinase regulator activity;GO:0005488//binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0005488//binding" "GO:0006351//transcription, DNA-templated;GO:0048469//cell maturation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0043549//regulation of kinase activity;GO:0008285//negative regulation of cell proliferation;GO:0007049//cell cycle;GO:0006351//transcription, DNA-templated;GO:0048469//cell maturation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0043549//regulation of kinase activity;GO:0008285//negative regulation of cell proliferation;GO:0022402//cell cycle process" gi|239052134|ref|NP_001155096.1|/1.34306e-148/cyclin-dependent kinase inhibitor 1C isoform 1 [Mus musculus] 227522 1027 2.58 2.263333333 -0.188921992 Down 0.221661213 Rpp38 ribonuclease P/MRP 38 subunit K14523|1|9e-136|485|mmu:227522|ribonucleases P/MRP protein subunit RPP38 [EC:3.1.26.5] GO:0043231//intracellular membrane-bounded organelle GO:0004549//tRNA-specific ribonuclease activity GO:0006399//tRNA metabolic process gi|755496771|ref|XP_011237272.1|/1.06885e-136/PREDICTED: ribonuclease P protein subunit p38 isoform X2 [Mus musculus] 21812 5647.24 2.533333333 2.213333333 -0.194816177 Down 0.221661213 Tgfbr1 "transforming growth factor, beta receptor I" K04674|1|0.0|987|mmu:21812|TGF-beta receptor type-1 [EC:2.7.11.30] - - - - 15426 2369 0.076666667 0.2 1.38332864 Up 0.221642409 Hoxc8 homeobox C8 K09305|1|2e-130|469|cfa:607625|homeobox protein HoxA/B/C5;K09308|2|2e-127|459|pale:102889189|homeobox protein HoxB/C/D8 GO:0043231//intracellular membrane-bounded organelle GO:0044212//transcription regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0003002//regionalization;GO:0001501//skeletal system development;GO:0030154//cell differentiation;GO:0006366//transcription from RNA polymerase II promoter gi|545547066|ref|XP_005637464.1|/1.35988e-129/PREDICTED: translation initiation factor IF-2 [Canis lupus familiaris] 67561 3821 10.67333333 9.93 -0.104145184 Down 0.221585994 Wdr48 WD repeat domain 48 K15361|1|0.0|1289|mmu:67561|WD repeat-containing protein 48 GO:0000323//lytic vacuole GO:0005488//binding GO:0070646//protein modification by small protein removal "gi|148677253|gb|EDL09200.1|/0/WD repeat domain 48, isoform CRA_b, partial [Mus musculus]" 100952 3466 10.18333333 10.92666667 0.101643474 Up 0.221585994 Emilin1 elastin microfibril interfacer 1 - GO:0031988//membrane-bounded vesicle;GO:0005578//proteinaceous extracellular matrix GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding GO:0043062//extracellular structure organization;GO:0010810//regulation of cell-substrate adhesion gi|74206993|dbj|BAE33288.1|/0/unnamed protein product [Mus musculus] 26905 3587 29.90333333 28.23333333 -0.082906842 Down 0.221548385 Eif2s3x "eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked" K03242|1|0.0|938|ocu:100344607|translation initiation factor 2 subunit 3 GO:0044444//cytoplasmic part "GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008135//translation factor activity, RNA binding" GO:0006412//translation;GO:0009154//purine ribonucleotide catabolic process gi|655875254|ref|XP_008270682.1|/0/PREDICTED: eukaryotic translation initiation factor 2 subunit 3 [Oryctolagus cuniculus] 635169 2209 0.226666667 0.38 0.745427173 Up 0.221501373 CK137956 cDNA sequence CK137956 - - - - gi|197927131|ref|NP_001128205.1|/0/uncharacterized protein C1orf94 homolog [Mus musculus] 74396 3376 0.19 0.073333333 -1.373458396 Down 0.221463763 4933407K13Rik RIKEN cDNA 4933407K13 gene - - - - - 108888 2426 27.52666667 29.19 0.084644293 Up 0.221454361 Atad3a "ATPase family, AAA domain containing 3A" K17681|1|0.0|887|mmu:108888|ATPase family AAA domain-containing protein 3A/B GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0005759//mitochondrial matrix GO:0032550;GO:0016462//pyrophosphatase activity GO:0006915//apoptotic process;GO:0040007//growth gi|239985513|ref|NP_849534.2|/0/ATPase family AAA domain-containing protein 3 [Mus musculus] 320712 4551.35 0.873333333 0.67 -0.38237131 Down 0.221379142 Abi3bp "ABI gene family, member 3 (NESH) binding protein" K10955|1|1e-18|99.0|fab:101821326|intestinal mucin-2 GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix GO:0005539//glycosaminoglycan binding;GO:0005539//glycosaminoglycan binding;GO:0005539//glycosaminoglycan binding;GO:0005539//glycosaminoglycan binding;GO:0005539//glycosaminoglycan binding GO:0043062//extracellular structure organization;GO:0010810//regulation of cell-substrate adhesion;GO:0043062//extracellular structure organization;GO:0010810//regulation of cell-substrate adhesion;GO:0043062//extracellular structure organization;GO:0010810//regulation of cell-substrate adhesion;GO:0043062//extracellular structure organization;GO:0010810//regulation of cell-substrate adhesion;GO:0043062//extracellular structure organization;GO:0010810//regulation of cell-substrate adhesion gi|62460376|ref|NP_001014422.1|/0/target of Nesh-SH3 isoform 4 precursor [Mus musculus] 78800 2199 0.08 0.2 1.321928095 Up 0.221313325 4930480K15Rik RIKEN cDNA 4930480K15 gene - - - - - 14081 3926.49 310.1933333 294.7866667 -0.073496408 Down 0.22129452 Acsl1 acyl-CoA synthetase long-chain family member 1 K01897|1|0.0|1376|mmu:14081|long-chain acyl-CoA synthetase [EC:6.2.1.3] GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0044439;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0044439 GO:0016878//acid-thiol ligase activity;GO:0032550;GO:0015645//fatty acid ligase activity;GO:0016405//CoA-ligase activity;GO:0016878//acid-thiol ligase activity;GO:0032550;GO:0015645//fatty acid ligase activity;GO:0016405//CoA-ligase activity GO:0015909//long-chain fatty acid transport;GO:0006639//acylglycerol metabolic process;GO:0070542//response to fatty acid;GO:0019221//cytokine-mediated signaling pathway;GO:0006631//fatty acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0045860//positive regulation of protein kinase activity;GO:0031667//response to nutrient levels;GO:0015909//long-chain fatty acid transport;GO:0006639//acylglycerol metabolic process;GO:0070542//response to fatty acid;GO:0019221//cytokine-mediated signaling pathway;GO:0006631//fatty acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0045860//positive regulation of protein kinase activity;GO:0031667//response to nutrient levels gi|31560705|ref|NP_032007.2|/0/long-chain-fatty-acid--CoA ligase 1 [Mus musculus] 215708 5229.53 1.556666667 1.83 0.233383599 Up 0.221285118 Fam73a "family with sequence similarity 73, member A" - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|240849401|ref|NP_001155847.1|/0/mitoguardin-1 isoform 2 [Mus musculus] 104886 3126 0.156666667 0.296666667 0.921144579 Up 0.221238106 Rab15 "RAB15, member RAS oncogene family" K07908|1|1e-110|403|ecb:100062462|Ras-related protein Rab-15 GO:0016020//membrane GO:0032550 GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization "gi|148704501|gb|EDL36448.1|/1.26444e-109/RAB15, member RAS oncogene family, isoform CRA_b, partial [Mus musculus]" 76633 911 1.393333333 1.153333333 -0.272730904 Down 0.221228704 1700112E06Rik RIKEN cDNA 1700112E06 gene - - - - - 328489 3526 1.176666667 1.416666667 0.267794658 Up 0.221228704 A630020A06 uncharacterized A630020A06 - - - - - 66108 1322 300.0166667 284.84 -0.07489089 Down 0.221228704 Ndufa9 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9" K03953|1|0.0|693|mmu:66108|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9 GO:0005746//mitochondrial respiratory chain "GO:0036094//small molecule binding;GO:0016651//oxidoreductase activity, acting on NAD(P)H" GO:0051234//establishment of localization;GO:0009746;GO:0044710;GO:0006091//generation of precursor metabolites and energy "gi|254692859|ref|NP_079634.2|/0/NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial precursor [Mus musculus]" 320893 1721 1.69 1.97 0.221172383 Up 0.221219301 6430562O15Rik RIKEN cDNA 6430562O15 gene K17406|1|2e-24|116|mmu:218506|small subunit ribosomal protein S27 - - - - 17966 4675.15 30.02 28.38 -0.081049388 Down 0.221209899 Nbr1 neighbor of Brca1 gene 1 K17987|1|0.0|1868|mmu:17966|next to BRCA1 gene 1 protein GO:0000323//lytic vacuole;GO:0031672//A band;GO:0005768//endosome;GO:0031982//vesicle;GO:0000323//lytic vacuole;GO:0031672//A band;GO:0005768//endosome;GO:0031982//vesicle;GO:0000323//lytic vacuole;GO:0031672//A band;GO:0005768//endosome;GO:0031982//vesicle;GO:0000323//lytic vacuole;GO:0031672//A band;GO:0005768//endosome;GO:0031982//vesicle GO:0046914//transition metal ion binding;GO:0019901//protein kinase binding;GO:0032182//ubiquitin-like protein binding;GO:0046914//transition metal ion binding;GO:0019901//protein kinase binding;GO:0032182//ubiquitin-like protein binding;GO:0046914//transition metal ion binding;GO:0019901//protein kinase binding;GO:0032182//ubiquitin-like protein binding;GO:0046914//transition metal ion binding;GO:0019901//protein kinase binding;GO:0032182//ubiquitin-like protein binding GO:0006461//protein complex assembly;GO:0043408//regulation of MAPK cascade;GO:0030278//regulation of ossification;GO:0001649//osteoblast differentiation;GO:0006914//autophagy;GO:0006461//protein complex assembly;GO:0043408//regulation of MAPK cascade;GO:0030278//regulation of ossification;GO:0001649//osteoblast differentiation;GO:0006914//autophagy;GO:0006461//protein complex assembly;GO:0043408//regulation of MAPK cascade;GO:0030278//regulation of ossification;GO:0001649//osteoblast differentiation;GO:0006914//autophagy;GO:0006461//protein complex assembly;GO:0043408//regulation of MAPK cascade;GO:0030278//regulation of ossification;GO:0001649//osteoblast differentiation;GO:0006914//autophagy "gi|148702107|gb|EDL34054.1|/0/neighbor of Brca1 gene 1, isoform CRA_a, partial [Mus musculus]" 223593 4038 10.59666667 9.863333333 -0.10346332 Down 0.221106473 E430025E21Rik RIKEN cDNA E430025E21 gene K18464|1|0.0|2185|mmu:223593|WASH complex subunit strumpellin GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0044765//single-organism transport gi|46048300|ref|NP_705776.2|/0/WASH complex subunit strumpellin [Mus musculus] 382406 2727 3.096666667 2.743333333 -0.174786166 Down 0.221078265 Poc1b POC1 centriolar protein B K16482|1|0.0|959|mmu:382406|centriolar protein POC1 - - - - 67329 1247 2.796666667 3.146666667 0.170116049 Up 0.221078265 1700018L02Rik RIKEN cDNA 1700018L02 gene K00944|1|3e-20|102|chx:102176121|nucleoside-triphosphate--adenylate kinase [EC:2.7.4.10] GO:0005740//mitochondrial envelope "GO:0032550;GO:0005515//protein binding;GO:0019205//nucleobase-containing compound kinase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0009151;GO:0006754//ATP biosynthetic process;GO:0051259//protein oligomerization;GO:0009208;GO:0022037//metencephalon development;GO:0021988//olfactory lobe development;GO:0006950//response to stress "gi|444722378|gb|ELW63075.1|/1.88241e-19/GTP:AMP phosphotransferase, mitochondrial [Tupaia chinensis]" 14760 1881.45 1.466666667 1.73 0.238231015 Up 0.221040656 Gpr19 G protein-coupled receptor 19 K04316|1|0.0|808|mmu:14760|G protein-coupled receptor 19 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway gi|564349359|ref|XP_006237582.1|/0/PREDICTED: probable G-protein coupled receptor 19 isoform X2 [Rattus norvegicus] 230895 15779.01 8.046666667 7.433333333 -0.114381966 Down 0.221031254 Vps13d vacuolar protein sorting 13D K19527|1|0.0|8236|mmu:230895|vacuolar protein sorting-associated protein 13D - - - gi|451172096|ref|NP_001263394.1|/0/vacuolar protein sorting-associated protein 13D isoform 2 [Mus musculus] 59041 3254 28.33333333 26.71333333 -0.084940331 Down 0.220956034 Stk25 serine/threonine kinase 25 (yeast) K08838|1|0.0|764|rno:373542|serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity;GO:0005515//protein binding GO:0051640//organelle localization;GO:0006464//cellular protein modification process;GO:0007409//axonogenesis;GO:0006796//phosphate-containing compound metabolic process;GO:0007154//cell communication;GO:0006950//response to stress gi|34576555|ref|NP_908938.1|/0/serine/threonine-protein kinase 25 [Rattus norvegicus] 66768 1464 1.02 1.246666667 0.289506617 Up 0.220918425 Pacrgl PARK2 co-regulated-like K15053|1|1e-52|210|bfo:BRAFLDRAFT_125501|charged multivesicular body protein 7;K03018|2|2e-08|63.2|cfo:105258154|DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6] - - - "gi|148705688|gb|EDL37635.1|/1.06495e-120/RIKEN cDNA 4933428G09, isoform CRA_b, partial [Mus musculus]" 13644 3571 1.263333333 1.036666667 -0.285283268 Down 0.220918425 Efs embryonal Fyn-associated substrate K05726|1|3e-26|124|lcm:102355909|breast cancer anti-estrogen resistance 1 - - - - 64082 2195.38 251.02 238.4433333 -0.074155869 Down 0.220871413 Popdc2 popeye domain containing 2 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|11612497|ref|NP_071713.1|/0/popeye domain-containing protein 2 isoform 2 [Mus musculus] 53857 1479 246.3633333 258.8866667 0.071533111 Up 0.220862011 Tuba8 "tubulin, alpha 8" K07374|1|0.0|871|oas:101118605|tubulin alpha - - - - 432486 5204 6.533333333 6.016666667 -0.118854817 Down 0.220711572 Gnptab "N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits" K08239|1|0.0|2505|mmu:432486|UDP-N-acetylglucosamine-lysosomal-enzyme [EC:2.7.8.17] - - - gi|50510849|dbj|BAD32410.1|/0/mKIAA1208 protein [Mus musculus] 59125 4316.5 26.49333333 28.09666667 0.08476961 Up 0.22070217 Nek7 NIMA (never in mitosis gene a)-related expressed kinase 7 K08857|1|6e-176|621|mmu:59125|NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0043169//cation binding;GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|987959688|ref|XP_015423941.1|/9.29516e-108/PREDICTED: serine/threonine-protein kinase Nek7 isoform X3 [Myotis davidii] 271305 3732 1.013333333 0.803333333 -0.335038177 Down 0.220626951 Phf21b PHD finger protein 21B K11643|1|2e-10|71.6|crg:105345699|chromodomain-helicase-DNA-binding protein 4 [EC:3.6.4.12];K14435|3|4e-10|70.5|xma:102225764|chromodomain-helicase-DNA-binding protein 5 [EC:3.6.4.12] - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - gi|264681520|ref|NP_001074635.2|/0/PHD finger protein 21B [Mus musculus] 78795 3217.54 1.023333333 0.81 -0.337282342 Down 0.220626951 Armc9 armadillo repeat containing 9 - - - - "gi|148708287|gb|EDL40234.1|/0/armadillo repeat containing 9, isoform CRA_g, partial [Mus musculus]" 24099 1710 1.01 0.796666667 -0.342307175 Down 0.220626951 Tnfsf13b "tumor necrosis factor (ligand) superfamily, member 13b" K05476|1|7e-167|589|mmu:24099|tumor necrosis factor ligand superfamily member 13B - - - - 71667 3665.66 16.24666667 17.24666667 0.086173803 Up 0.220589341 Tmem248 transmembrane protein 248 K20131|1|3e-167|592|fch:102053701|Rab5 GDP/GTP exchange factor;K12662|3|9e-11|72.4|smm:Smp_169060|U4/U6 small nuclear ribonucleoprotein PRP4 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|880937805|ref|XP_012976162.1|/0/PREDICTED: transmembrane protein 248 isoform X1 [Mesocricetus auratus] 23980 1217 228.83 240.3066667 0.070600468 Up 0.220589341 Pebp1 phosphatidylethanolamine binding protein 1 K17439|1|3e-79|298|acs:100555543|large subunit ribosomal protein L35;K12367|2|3e-53|211|tsp:Tsp_02455|dedicator of cytokinesis protein 2 - - - gi|84794552|ref|NP_061346.2|/6.07405e-108/phosphatidylethanolamine-binding protein 1 [Mus musculus] 231931 1612 27.38333333 28.97 0.08126161 Up 0.220589341 Gimap6 "GTPase, IMAP family member 6" - - GO:0032550 - gi|23346632|ref|NP_694815.1|/5.94148e-160/GTPase IMAP family member 6 [Mus musculus] 107305 2415 15.63333333 16.63 0.089162747 Up 0.220589341 Vps37c vacuolar protein sorting 37C K12185|1|1e-135|486|mmu:107305|ESCRT-I complex subunit VPS37 GO:0043231//intracellular membrane-bounded organelle - GO:0051234//establishment of localization "gi|148709431|gb|EDL41377.1|/2.28254e-140/vacuolar protein sorting 37C (yeast), isoform CRA_b, partial [Mus musculus]" 102371 2283 252.19 240.7766667 -0.066815481 Down 0.220570537 Myzap myocardial zonula adherens protein K18669|1|5e-14|82.4|cin:100176948|dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1];K17751|2|1e-12|78.2|crg:105329786|myosin heavy chain 6/7;K10352|4|1e-12|78.2|xma:102228705|myosin heavy chain;K10402|5|4e-12|76.3|xtr:100145121|kinesin family member 20 - - - - 21887 5170.59 5.013333333 5.47 0.125770672 Up 0.22054233 Tle3 transducin-like enhancer of split 3 K04497|1|0.0|1211|dre:30206|groucho GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated;GO:0007166//cell surface receptor signaling pathway;GO:0048869//cellular developmental process;GO:0007166//cell surface receptor signaling pathway;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0048869//cellular developmental process;GO:0007166//cell surface receptor signaling pathway;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated" gi|28972780|dbj|BAC65806.1|/0/mKIAA1547 protein [Mus musculus] 76100 743 0.48 0.316666667 -0.600069393 Down 0.220532927 5830454E08Rik RIKEN cDNA 5830454E08 gene - - - - gi|26383522|dbj|BAC25540.1|/1.02547e-64/unnamed protein product [Mus musculus] 66902 2558 10.23 10.95 0.098124725 Up 0.220495318 Mtap methylthioadenosine phosphorylase K00772|1|6e-163|577|mmu:66902|5'-methylthioadenosine phosphorylase [EC:2.4.2.28] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0016763//transferase activity, transferring pentosyl groups;GO:0016758//transferase activity, transferring hexosyl groups" GO:0046495//nicotinamide riboside metabolic process;GO:0048545//response to steroid hormone;GO:0006576//cellular biogenic amine metabolic process;GO:0006790//sulfur compound metabolic process;GO:0043102;GO:0043101//purine-containing compound salvage "gi|148699009|gb|EDL30956.1|/4.13469e-172/methylthioadenosine phosphorylase, isoform CRA_b, partial [Mus musculus]" 53869 2333 27.51333333 29.09666667 0.080722949 Up 0.22046711 Rab11a "RAB11A, member RAS oncogene family" K07904|1|1e-118|430|mdo:100018220|Ras-related protein Rab-11A GO:0043005//neuron projection;GO:0032991//macromolecular complex;GO:0032155;GO:0010008//endosome membrane;GO:0030666//endocytic vesicle membrane GO:0000149//SNARE binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0042044//fluid transport;GO:0007009//plasma membrane organization;GO:0015031//protein transport;GO:0032401//establishment of melanosome localization;GO:0009154//purine ribonucleotide catabolic process;GO:0030307//positive regulation of cell growth;GO:0035556//intracellular signal transduction;GO:0016192//vesicle-mediated transport;GO:0030030//cell projection organization;GO:0048168//regulation of neuronal synaptic plasticity gi|194387154|dbj|BAG59943.1|/7.27918e-121/unnamed protein product [Homo sapiens] 53901 3297.32 244.8966667 234.0966667 -0.065068745 Down 0.220401294 Rcan2 regulator of calcineurin 2 K17903|1|4e-111|405|mmu:53901|calcipressin-2 - GO:0036094//small molecule binding;GO:0019903//protein phosphatase binding;GO:0036094//small molecule binding;GO:0036094//small molecule binding;GO:0036094//small molecule binding;GO:0019903//protein phosphatase binding GO:0007399//nervous system development;GO:0019932//second-messenger-mediated signaling;GO:0019932//second-messenger-mediated signaling;GO:0019932//second-messenger-mediated signaling;GO:0007399//nervous system development;GO:0019932//second-messenger-mediated signaling gi|13447392|ref|NP_085101.1|/3.30129e-110/calcipressin-2 isoform 2 [Mus musculus] 59011 1294 0.086666667 0.21 1.276840205 Up 0.220382489 Myoz1 myozenin 1 - GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle GO:0008092//cytoskeletal protein binding - gi|10946924|ref|NP_067483.1|/1.62364e-130/myozenin-1 [Mus musculus] 226757 7063 15.50333333 16.49333333 0.08930456 Up 0.220335477 Wdr26 WD repeat domain 26 K14963|1|1e-22|113|loa:LOAG_03831|COMPASS component SWD3 GO:0031981//nuclear lumen - - gi|264681550|ref|NP_663489.4|/0/WD repeat-containing protein 26 [Mus musculus] 22321 4224 15.83666667 14.85 -0.092805775 Down 0.220335477 Vars valyl-tRNA synthetase K01873|1|0.0|2227|mmu:22321|valyl-tRNA synthetase [EC:6.1.1.9] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0052689//carboxylic ester hydrolase activity;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation gi|255069795|ref|NP_035820.3|/0/valine--tRNA ligase [Mus musculus] 64009 4980.12 15.95 14.96 -0.092446249 Down 0.220335477 Syne1 "spectrin repeat containing, nuclear envelope 1" K19326|1|0.0|2369|cge:100769533|nesprin-1 GO:0097060//synaptic membrane;GO:0015630//microtubule cytoskeleton;GO:0034992//microtubule organizing center attachment site;GO:0030425//dendrite;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0097060//synaptic membrane;GO:0015630//microtubule cytoskeleton;GO:0034992//microtubule organizing center attachment site;GO:0030425//dendrite;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0042802//identical protein binding;GO:0042802//identical protein binding GO:0007010//cytoskeleton organization;GO:0006898//receptor-mediated endocytosis;GO:0051647//nucleus localization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0043578//nuclear matrix organization;GO:0007010//cytoskeleton organization;GO:0006898//receptor-mediated endocytosis;GO:0051647//nucleus localization;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0043578//nuclear matrix organization gi|119120865|ref|NP_001073154.1|/0/nesprin-1 isoform 3 [Mus musculus] 230967 3293 16.85666667 15.87 -0.08701715 Down 0.220335477 Cep104 centrosomal protein 104 K16458|1|0.0|1717|mmu:230967|centrosomal protein CEP104 GO:0005813//centrosome GO:0008144//drug binding;GO:0016597//amino acid binding - gi|29244100|ref|NP_808341.1|/0/centrosomal protein of 104 kDa [Mus musculus] 21857 902 3.606666667 3.996666667 0.14813116 Up 0.220326075 Timp1 tissue inhibitor of metalloproteinase 1 K16451|1|1e-103|378|mmu:21857|metallopeptidase inhibitor 1 GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix GO:0043169//cation binding;GO:0004866//endopeptidase inhibitor activity;GO:0019899//enzyme binding;GO:0043169//cation binding;GO:0004866//endopeptidase inhibitor activity;GO:0019899//enzyme binding GO:0001501//skeletal system development;GO:0048469//cell maturation;GO:0030336//negative regulation of cell migration;GO:0009611//response to wounding;GO:0008202//steroid metabolic process;GO:0006915//apoptotic process;GO:0006509//membrane protein ectodomain proteolysis;GO:0044092//negative regulation of molecular function;GO:0009725//response to hormone;GO:0001501//skeletal system development;GO:0048469//cell maturation;GO:0030336//negative regulation of cell migration;GO:0009611//response to wounding;GO:0008202//steroid metabolic process;GO:0006915//apoptotic process;GO:0006509//membrane protein ectodomain proteolysis;GO:0044092//negative regulation of molecular function;GO:0009725//response to hormone "gi|148668414|gb|EDL00738.1|/1.19996e-106/tissue inhibitor of metalloproteinase 1, isoform CRA_b, partial [Mus musculus]" 12866 754 237.2333333 226.62 -0.066031546 Down 0.220326075 Cox7a2 cytochrome c oxidase subunit VIIa 2 K02270|1|2e-39|164|mmu:12866|cytochrome c oxidase subunit 7a GO:0005743//mitochondrial inner membrane GO:0015002//heme-copper terminal oxidase activity GO:0044710 "gi|31981830|ref|NP_034075.2|/1.30863e-38/cytochrome c oxidase subunit 7A2, mitochondrial precursor [Mus musculus]" 16881 3111 2.143333333 1.85 -0.212330966 Down 0.220232051 Lig1 "ligase I, DNA, ATP-dependent" K10747|1|0.0|1657|mmu:16881|DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] - - - "gi|148706114|gb|EDL38061.1|/0/ligase I, DNA, ATP-dependent, isoform CRA_b, partial [Mus musculus]" 56187 2547 7.896666667 7.296666667 -0.114006244 Down 0.220213246 Rabggta "Rab geranylgeranyl transferase, a subunit" K14050|1|0.0|1060|mmu:56187|geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60] - GO:0046914//transition metal ion binding;GO:0004661//protein geranylgeranyltransferase activity GO:0018342//protein prenylation;GO:0050953//sensory perception of light stimulus "gi|148704299|gb|EDL36246.1|/0/Rab geranylgeranyl transferase, a subunit, isoform CRA_a, partial [Mus musculus]" 212706 2593 7.296666667 7.893333333 0.113397126 Up 0.220213246 N4bp3 NEDD4 binding protein 3 - GO:0044424;GO:0031982//vesicle - - gi|52632423|gb|AAH06740.2|/0/RIKEN cDNA C330016O10 gene [Mus musculus] 232413 2222 0.4 0.573333333 0.519374159 Up 0.220213246 Clec12a "C-type lectin domain family 12, member a" K17516|1|8e-134|480|mmu:232413|C-type lectin domain family 12 member A GO:0044464;GO:0031224//intrinsic component of membrane GO:0019902//phosphatase binding GO:0002682//regulation of immune system process "gi|148667503|gb|EDK99919.1|/2.06005e-148/C-type lectin domain family 12, member a, isoform CRA_b, partial [Mus musculus]" 67489 2849.95 7.81 8.41 0.106783252 Up 0.220213246 Ap4b1 "adaptor-related protein complex AP-4, beta 1" K12401|1|0.0|1449|mmu:67489|AP-4 complex subunit beta-1 GO:0043231//intracellular membrane-bounded organelle;GO:0030119//AP-type membrane coat adaptor complex;GO:0043231//intracellular membrane-bounded organelle;GO:0030119//AP-type membrane coat adaptor complex;GO:0043231//intracellular membrane-bounded organelle;GO:0030119//AP-type membrane coat adaptor complex GO:0022892//substrate-specific transporter activity;GO:0022892//substrate-specific transporter activity;GO:0022892//substrate-specific transporter activity GO:0015031//protein transport;GO:0015031//protein transport;GO:0015031//protein transport gi|254588022|ref|NP_001157025.1|/0/AP-4 complex subunit beta-1 isoform b [Mus musculus] 78317 4959 0.7 0.903333333 0.367903524 Up 0.220194441 Ccdc88b coiled-coil domain containing 88B "K16510|1|7e-28|129|asn:102371867|ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1];K12337|4|1e-07|62.4|shr:100918494|inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate;K16611|5|1e-07|62.4|hgl:101712752|protein HOOK2" GO:0044424 GO:0015631//tubulin binding - gi|124486839|ref|NP_001074760.1|/0/coiled-coil domain-containing protein 88B precursor [Mus musculus] 59022 678 213.82 203.6033333 -0.070635623 Down 0.220175637 Edf1 endothelial differentiation-related factor 1 K03627|1|3e-78|293|ngi:103741189|putative transcription factor GO:0005667//transcription factor complex GO:0003712//transcription cofactor activity;GO:0016741;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0008080//N-acetyltransferase activity;GO:0005515//protein binding "GO:0048869//cellular developmental process;GO:0006629//lipid metabolic process;GO:0051099//positive regulation of binding;GO:0003158//endothelium development;GO:0006351//transcription, DNA-templated" "gi|148708591|gb|EDL40538.1|/4.53382e-79/mCG14687, partial [Mus musculus]" 21817 3549 201.0166667 211.2033333 0.071317481 Up 0.220166234 Tgm2 "transglutaminase 2, C polypeptide" K05625|1|0.0|1390|mmu:21817|transglutaminase 2 [EC:2.3.2.13] GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0031012//extracellular matrix "GO:0032550;GO:0005515//protein binding;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0046872//metal ion binding;GO:0016755//transferase activity, transferring amino-acyl groups" GO:0006909//phagocytosis;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007155//cell adhesion;GO:0018199;GO:0008284//positive regulation of cell proliferation;GO:0051259//protein oligomerization;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0012502//induction of programmed cell death;GO:0006954//inflammatory response;GO:0007435//salivary gland morphogenesis "gi|148674308|gb|EDL06255.1|/0/transglutaminase 2, C polypeptide, isoform CRA_a, partial [Mus musculus]" 56349 3874 4.62 4.2 -0.137503524 Down 0.220119222 Net1 neuroepithelial cell transforming gene 1 K20045|1|9e-31|139|isc:IscW_ISCW007883|intersectin GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding GO:0034614//cellular response to reactive oxygen species;GO:0006915//apoptotic process;GO:0010212//response to ionizing radiation;GO:0034614//cellular response to reactive oxygen species;GO:0006915//apoptotic process;GO:0010212//response to ionizing radiation gi|114145477|ref|NP_062645.2|/0/neuroepithelial cell-transforming gene 1 protein isoform 1 [Mus musculus] 20656 3824 200.3066667 190.33 -0.07370746 Down 0.220119222 Sod2 "superoxide dismutase 2, mitochondrial" "K04564|1|9e-110|401|mmu:20656|superoxide dismutase, Fe-Mn family [EC:1.15.1.1]" GO:0005759//mitochondrial matrix;GO:0019866//organelle inner membrane GO:0016209//antioxidant activity;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0033483;GO:0048534//hematopoietic or lymphoid organ development;GO:0006809//nitric oxide biosynthetic process;GO:0050954//sensory perception of mechanical stimulus;GO:0042391//regulation of membrane potential;GO:0055080//cation homeostasis;GO:0050931//pigment cell differentiation;GO:0019222//regulation of metabolic process;GO:0022900//electron transport chain;GO:0045471//response to ethanol;GO:0051260//protein homooligomerization;GO:0045444//fat cell differentiation;GO:0044708//single-organism behavior;GO:0006801//superoxide metabolic process;GO:0042743//hydrogen peroxide metabolic process;GO:0010212//response to ionizing radiation;GO:0030182//neuron differentiation;GO:0050880//regulation of blood vessel size;GO:0006790//sulfur compound metabolic process;GO:0000302//response to reactive oxygen species;GO:0002237//response to molecule of bacterial origin;GO:0010038//response to metal ion;GO:0008637//apoptotic mitochondrial changes;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0033273//response to vitamin;GO:0043066//negative regulation of apoptotic process;GO:0003068;GO:0009593//detection of chemical stimulus;GO:0009611//response to wounding gi|832851|gb|AAB60902.1|/7.88414e-109/manganese superoxide dismutase [Mus musculus] 434246 2472 206.34 216.1166667 0.066786814 Up 0.22007221 Trim72 tripartite motif-containing 72 K12036|1|0.0|931|mmu:434246|tripartite motif-containing protein 72 GO:0012506//vesicle membrane;GO:0005886//plasma membrane GO:0046914//transition metal ion binding;GO:0005543//phospholipid binding GO:0016192//vesicle-mediated transport;GO:0051259//protein oligomerization;GO:0007009//plasma membrane organization;GO:0003008;GO:0048513//animal organ development gi|121247302|ref|NP_001073401.1|/0/tripartite motif-containing protein 72 [Mus musculus] 328381 1296 0.153333333 0.04 -1.938599455 Down 0.220062808 Sh2d4b SH2 domain containing 4B K17577|1|2e-77|291|cmk:103186732|SH2 domain-containing protein 4A - - - gi|58866052|ref|NP_808484.2|/0/SH2 domain-containing protein 4B [Mus musculus] 12511 2917 0.036666667 0.143333333 1.966833136 Up 0.220062808 Cd6 CD6 antigen K06456|1|0.0|1219|mmu:12511|CD6 antigen GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane GO:0019900//kinase binding;GO:0038024//cargo receptor activity;GO:0019900//kinase binding;GO:0038024//cargo receptor activity GO:0022610;GO:0022610 "gi|148709435|gb|EDL41381.1|/0/CD6 antigen, isoform CRA_a, partial [Mus musculus]" 67979 2813 30.04 28.49333333 -0.076260406 Down 0.220053406 Atad1 "ATPase family, AAA domain containing 1" K13254|1|2e-52|210|aga:AgaP_AGAP002334|spastin [EC:3.6.4.3] GO:0097060//synaptic membrane;GO:0044439 GO:0032550;GO:0017111//nucleoside-triphosphatase activity "GO:0002090//regulation of receptor internalization;GO:0007611//learning or memory;GO:0035249//synaptic transmission, glutamatergic;GO:0009154//purine ribonucleotide catabolic process" gi|755563588|ref|XP_006527375.2|/0/PREDICTED: ATPase family AAA domain-containing protein 1 isoform X2 [Mus musculus] 14704 1699 1.196666667 1.433333333 0.260352816 Up 0.220053406 Gng3 "guanine nucleotide binding protein (G protein), gamma 3" K04540|1|1e-37|160|ssc:100620948|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 GO:0031234//extrinsic component of cytoplasmic side of plasma membrane GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0031701//angiotensin receptor binding GO:0007166//cell surface receptor signaling pathway;GO:0015980//energy derivation by oxidation of organic compounds;GO:0007267//cell-cell signaling;GO:0033762//response to glucagon;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0006468//protein phosphorylation;GO:0009154//purine ribonucleotide catabolic process gi|795167886|ref|XP_011798065.1|/2.74329e-54/PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [Colobus angolensis palliatus] 68241 816 186.8 196.2933333 0.071516721 Up 0.219996991 Fam195a "family with sequence similarity 195, member A" - - - - gi|13386124|ref|NP_080909.1|/2.47831e-89/protein FAM195A [Mus musculus] 109181 6448 1.11 0.893333333 -0.313289177 Down 0.219959382 Trip11 thyroid hormone receptor interactor 11 K20478|1|8e-48|196|dre:557772|golgin subfamily B member 1 - - - gi|226531227|ref|NP_082722.1|/0/thyroid receptor-interacting protein 11 [Mus musculus] 110033 2086 1.15 0.926666667 -0.311511479 Down 0.219959382 Kif22 kinesin family member 22 K10403|1|0.0|1173|mmu:110033|kinesin family member 22 GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044427;GO:0005924//cell-substrate adherens junction GO:0032550;GO:0003676//nucleic acid binding;GO:0003774//motor activity GO:0006259//DNA metabolic process;GO:0006928//movement of cell or subcellular component gi|21704182|ref|NP_663563.1|/0/kinesin-like protein KIF22 [Mus musculus] 17279 2914 0.166666667 0.306666667 0.879705766 Up 0.219949979 Melk maternal embryonic leucine zipper kinase K08799|1|0.0|1244|mmu:17279|maternal embryonic leucine zipper kinase [EC:2.7.11.1] GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0032550;GO:0046872//metal ion binding;GO:0004713//protein tyrosine kinase activity GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0008283//cell proliferation "gi|148670479|gb|EDL02426.1|/0/maternal embryonic leucine zipper kinase, isoform CRA_b, partial [Mus musculus]" 20494 4088 0.3 0.163333333 -0.877143252 Down 0.219949979 Slc10a2 "solute carrier family 10, member 2" "K14342|1|0.0|670|mmu:20494|solute carrier family 10 (sodium/bile acid cotransporter), member 2" - - - - 320528 11523 2.34 2.043333333 -0.195583957 Down 0.219940577 Vps13c vacuolar protein sorting 13C K19525|1|0.0|6858|mmu:320528|vacuolar protein sorting-associated protein 13A/C - - - gi|122114537|ref|NP_796158.2|/0/vacuolar protein sorting-associated protein 13C [Mus musculus] 66293 1254.9 1.996666667 2.3 0.204040359 Up 0.219940577 1810032O08Rik RIKEN cDNA 1810032O08 gene - - - - - 66580 3392 2.28 1.98 -0.203533394 Down 0.219940577 Esf1 ESF1 nucleolar pre-rRNA processing protein homolog - - - - - 101772 4614 2.35 2.046666667 -0.199384602 Down 0.219940577 Ano1 "anoctamin 1, calcium activated chloride channel" K19496|1|0.0|1929|mmu:101772|anoctamin-1 GO:0034702//ion channel complex;GO:0044424 GO:0005254//chloride channel activity GO:0015698//inorganic anion transport;GO:0006873//cellular ion homeostasis;GO:0044767//single-organism developmental process "gi|148686318|gb|EDL18265.1|/0/mCG126938, isoform CRA_h, partial [Mus musculus]" 380977 1348.3 1.983333333 2.283333333 0.20321432 Up 0.219940577 A330009N23Rik RIKEN cDNA A330009N23 gene - - - - gi|148672112|gb|EDL04059.1|/1.26253e-45/mCG140896 [Mus musculus] 338535 2773 0.04 0.146666667 1.874469118 Up 0.21991237 E030013I19Rik RIKEN cDNA E030013I19 gene - - - - - 53624 989 0.206666667 0.086666667 -1.253756592 Down 0.219827748 Cldn7 claudin 7 K06087|1|4e-106|387|mmu:53624|claudin GO:0044459;GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex GO:0005515//protein binding;GO:0005515//protein binding GO:0016337//single organismal cell-cell adhesion;GO:0016337//single organismal cell-cell adhesion gi|8393144|ref|NP_058583.1|/2.03243e-105/claudin-7 precursor [Mus musculus] 71452 1981.39 183.1733333 174.15 -0.072879016 Down 0.219818346 Ankrd40 ankyrin repeat domain 40 "K18410|1|2e-08|63.2|lgi:LOTGIDRAFT_168837|ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1;K10799|2|9e-08|60.8|aqu:100637824|tankyrase [EC:2.4.2.30];K03426|3|3e-07|59.3|obi:106875705|NAD+ diphosphatase [EC:3.6.1.22];K17566|4|4e-07|58.9|crg:105317557|protein phosphatase 1 regulatory subunit 27" - - - "gi|148683972|gb|EDL15919.1|/2.6125e-143/ankyrin repeat domain 40, isoform CRA_b, partial [Mus musculus]" 170770 1976 2.523333333 2.85 0.17563112 Up 0.219799541 Bbc3 BCL2 binding component 3 K10132|1|2e-61|239|mmu:170770|Bcl-2-binding component 3 GO:0043231//intracellular membrane-bounded organelle GO:0019904//protein domain specific binding GO:0008637//apoptotic mitochondrial changes;GO:0048519;GO:0006874//cellular calcium ion homeostasis;GO:0007417//central nervous system development;GO:0032879//regulation of localization;GO:0040007//growth;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010259//multicellular organism aging;GO:0010822//positive regulation of mitochondrion organization;GO:0070234//positive regulation of T cell apoptotic process;GO:0034976//response to endoplasmic reticulum stress;GO:0012502//induction of programmed cell death;GO:0030154//cell differentiation;GO:0010950//positive regulation of endopeptidase activity;GO:0010212//response to ionizing radiation gi|568944933|ref|XP_006539638.1|/1.7666e-63/PREDICTED: bcl-2-binding component 3 isoform X2 [Mus musculus] 71296 1151.23 2.43 2.76 0.183711953 Up 0.219799541 Crnde colorectal neoplasia differentially expressed (non-protein coding) - - - - - 15400 2543 0.233333333 0.383333333 0.716207034 Up 0.219771334 Hoxa3 homeobox A3 K09303|1|7e-180|633|mmu:15400|homeobox protein HoxA/B/D3 GO:0031981//nuclear lumen GO:0003677//DNA binding;GO:0019904//protein domain specific binding "GO:0035270//endocrine system development;GO:0048534//hematopoietic or lymphoid organ development;GO:0003002//regionalization;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0021563//glossopharyngeal nerve development;GO:0001501//skeletal system development;GO:0048562//embryonic organ morphogenesis;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation" gi|46275824|ref|NP_034582.1|/5.91416e-179/homeobox protein Hox-A3 [Mus musculus] 12050 3476 15.63 14.65666667 -0.092760747 Down 0.219724322 Bcl2l2 BCL2-like 2 K02163|1|3e-87|326|mmu:12050|apoptosis regulator BCL-W GO:0005740//mitochondrial envelope GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding GO:0006915//apoptotic process;GO:0048232//male gamete generation;GO:0008283//cell proliferation gi|32185285|gb|AAO64470.1|/2.61338e-87/BCL-WEL [Rattus norvegicus] 66266 1143 16.73333333 15.76666667 -0.085847181 Down 0.219724322 Eapp E2F-associated phosphoprotein - - - - - 227695 1838 15.80666667 16.77666667 0.085922935 Up 0.219724322 D2Wsu81e "DNA segment, Chr 2, Wayne State University 81, expressed" K09142|1|0.0|671|mmu:227695|uncharacterized protein - - - "gi|148676498|gb|EDL08445.1|/0/DNA segment, Chr 2, Wayne State University 81, expressed, isoform CRA_d [Mus musculus]" 52430 1314.77 14.9 15.86666667 0.090686742 Up 0.219724322 Echdc2 enoyl Coenzyme A hydratase domain containing 2 K05607|1|3e-79|298|dre:445182|methylglutaconyl-CoA hydratase [EC:4.2.1.18] - - - gi|74150361|dbj|BAE32227.1|/4.63858e-135/unnamed protein product [Mus musculus] 58193 2945.62 5.743333333 6.253333333 0.122737126 Up 0.219667908 Extl2 exostoses (multiple)-like 2 "K02369|1|7e-177|624|mmu:58193|alpha-1,4-N-acetylglucosaminyltransferase EXTL2 [EC:2.4.1.223]" GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0008376//acetylgalactosaminyltransferase activity;GO:0043169//cation binding;GO:0008376//acetylgalactosaminyltransferase activity;GO:0043169//cation binding;GO:0008376//acetylgalactosaminyltransferase activity GO:1901071;GO:1901071;GO:1901071 gi|254553481|ref|NP_067363.3|/5.28421e-176/exostosin-like 2 isoform a [Mus musculus] 77877 3974 6.29 5.783333333 -0.12115876 Down 0.219667908 6030458C11Rik RIKEN cDNA 6030458C11 gene "K03847|1|4e-06|40.0|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - gi|261599071|ref|NP_001159832.1|/1.40475e-68/UPF0489 protein C5orf22 homolog isoform a [Mus musculus] 394432 3294 0.48 0.656666667 0.452126818 Up 0.21951747 Ugt1a7c "UDP glucuronosyltransferase 1 family, polypeptide A7C" K00699|1|0.0|1068|mmu:394432|glucuronosyltransferase [EC:2.4.1.17] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0042802//identical protein binding;GO:0030234//enzyme regulator activity;GO:0046983//protein dimerization activity;GO:0008194//UDP-glycosyltransferase activity GO:0006631//fatty acid metabolic process;GO:0009804//coumarin metabolic process;GO:0006706//steroid catabolic process;GO:0044092//negative regulation of molecular function;GO:0006805//xenobiotic metabolic process;GO:0009812//flavonoid metabolic process;GO:0006464//cellular protein modification process;GO:0014070//response to organic cyclic compound gi|47059123|ref|NP_964004.1|/0/UDP-glucuronosyltransferase 1-7C precursor [Mus musculus] 105689 15269 2.516666667 2.21 -0.187467774 Down 0.219461055 Mycbp2 MYC binding protein 2 K10693|1|0.0|8806|mmu:105689|E3 ubiquitin-protein ligase MYCBP2 [EC:2.3.2.27] - - - gi|127141012|ref|NP_997098.2|/0/E3 ubiquitin-protein ligase MYCBP2 [Mus musculus] 13845 4164 2.26 2.57 0.185445587 Up 0.219461055 Ephb3 Eph receptor B3 K05112|1|0.0|1905|mmu:13845|Eph receptor B3 [EC:2.7.10.1] GO:0044464;GO:0016021//integral component of membrane GO:0005003//ephrin receptor activity;GO:0032550 GO:0048534//hematopoietic or lymphoid organ development;GO:0007411//axon guidance;GO:0007416//synapse assembly;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048870//cell motility;GO:0016337//single organismal cell-cell adhesion;GO:0016358//dendrite development;GO:0021537//telencephalon development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0021955//central nervous system neuron axonogenesis;GO:0006468//protein phosphorylation "gi|148665184|gb|EDK97600.1|/0/Eph receptor B3, isoform CRA_a, partial [Mus musculus]" 78108 1933 2.213333333 2.526666667 0.191014607 Up 0.219461055 Particl promoter of Mat2a antisense radiation induced circulating long non-coding RNA K00789|1|1e-08|64.3|pale:102898454|S-adenosylmethionine synthetase [EC:2.5.1.6] - - - - 20969 3057 2.233333333 2.54 0.185629902 Up 0.219461055 Sdc1 syndecan 1 K06257|1|8e-120|434|mmu:20969|syndecan 1 GO:0032991//macromolecular complex;GO:0009986//cell surface;GO:0005924//cell-substrate adherens junction;GO:0044425;GO:0044424 GO:0005515//protein binding GO:0006952//defense response;GO:0016055//Wnt signaling pathway;GO:0010038//response to metal ion;GO:0022610;GO:0046683//response to organophosphorus;GO:0000302//response to reactive oxygen species;GO:0009611//response to wounding;GO:0009887//organ morphogenesis;GO:0051146//striated muscle cell differentiation;GO:0031960//response to corticosteroid;GO:0045445//myoblast differentiation;GO:0003006//developmental process involved in reproduction gi|568977654|ref|XP_006515109.1|/6.51606e-119/PREDICTED: syndecan-1 isoform X2 [Mus musculus] 18023 4359.05 181.8533333 173.8333333 -0.065070618 Down 0.219432848 Nfe2l1 "nuclear factor, erythroid derived 2,-like 1" K09040|1|0.0|961|mmu:18023|nuclear factor erythroid 2-related factor 1/3 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0030099//myeloid cell differentiation;GO:0006351//transcription, DNA-templated;GO:0030099//myeloid cell differentiation;GO:0006351//transcription, DNA-templated;GO:0030099//myeloid cell differentiation;GO:0006351//transcription, DNA-templated;GO:0030099//myeloid cell differentiation;GO:0006351//transcription, DNA-templated;GO:0030099//myeloid cell differentiation;GO:0006351//transcription, DNA-templated;GO:0030099//myeloid cell differentiation;GO:0006351//transcription, DNA-templated" gi|47847522|dbj|BAD21433.1|/0/mFLJ00380 protein [Mus musculus] 12631 1196 150.53 158.4866667 0.074310434 Up 0.219404641 Cfl1 "cofilin 1, non-muscle" K05765|1|5e-107|390|bacu:102998574|cofilin - - - - 66687 3779 8.026666667 7.44 -0.109498365 Down 0.219404641 Tbc1d15 "TBC1 domain family, member 15" K20168|1|0.0|1335|mmu:66687|TBC1 domain family member 15 GO:0043231//intracellular membrane-bounded organelle - - gi|255958202|ref|NP_079982.3|/0/TBC1 domain family member 15 [Mus musculus] 142682 6476 7.803333333 7.21 -0.114091269 Down 0.219404641 Zcchc14 "zinc finger, CCHC domain containing 14" K11722|1|1e-70|271|chx:102188667|bromodomain-containing protein 4;K11791|2|7e-06|57.0|chx:102190118|DDB1- and CUL4-associated factor 15 - GO:0046914//transition metal ion binding;GO:0005543//phospholipid binding;GO:0097159//organic cyclic compound binding GO:0044763 gi|568956123|ref|XP_006530730.1|/0/PREDICTED: zinc finger CCHC domain-containing protein 14 isoform X1 [Mus musculus] 74392 6078 10.45666667 9.753333333 -0.10045576 Down 0.219367031 Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like K20282|1|7e-20|103|spu:578096|GRIP and coiled-coil domain-containing protein 2;K20283|3|1e-19|102|mde:101892550|golgin subfamily A member 4 GO:0015630//microtubule cytoskeleton;GO:0005911//cell-cell junction;GO:0005884//actin filament;GO:0015630//microtubule cytoskeleton;GO:0005911//cell-cell junction;GO:0005884//actin filament - GO:0007019//microtubule depolymerization;GO:0030042//actin filament depolymerization;GO:0022610;GO:0048870//cell motility;GO:0009653//anatomical structure morphogenesis;GO:0007019//microtubule depolymerization;GO:0030042//actin filament depolymerization;GO:0022610;GO:0048870//cell motility;GO:0009653//anatomical structure morphogenesis gi|224922837|ref|NP_001139298.1|/0/cytospin-A isoform a [Mus musculus] 230904 1260 0.046666667 0.16 1.777607579 Up 0.219357629 Fbxo2 F-box protein 2 K10099|1|2e-138|494|mmu:230904|F-box protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0030425//dendrite;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0044444//cytoplasmic part GO:0042277//peptide binding;GO:0005515//protein binding GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0008283//cell proliferation;GO:0009100//glycoprotein metabolic process gi|33859801|ref|NP_789818.1|/1.71584e-137/F-box only protein 2 [Mus musculus] 19210 3424 15.62333333 16.58333333 0.086031731 Up 0.219329422 Ptdss1 phosphatidylserine synthase 1 K08729|1|0.0|873|mmu:19210|phosphatidylserine synthase 1 [EC:2.7.8.-] GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane GO:0003824//catalytic activity GO:0006658//phosphatidylserine metabolic process gi|31560651|ref|NP_032985.2|/0/phosphatidylserine synthase 1 [Mus musculus] 67444 1368 26.73 28.22666667 0.078598931 Up 0.21928241 Ilkap integrin-linked kinase-associated serine/threonine phosphatase 2C K17500|1|0.0|750|mmu:67444|integrin-linked kinase-associated serine/threonine phosphatase 2C [EC:3.1.3.16] GO:0044424 GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity GO:0000084//mitotic S phase;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0051726//regulation of cell cycle gi|39930415|ref|NP_075832.1|/0/integrin-linked kinase-associated serine/threonine phosphatase 2C [Mus musculus] 68135 1254 151.93 159.61 0.071144272 Up 0.219263605 Eif3h "eukaryotic translation initiation factor 3, subunit H" K03247|1|9e-152|538|mmu:68135|translation initiation factor 3 subunit H GO:0043234//protein complex;GO:0043227//membrane-bounded organelle;GO:0044424 "GO:0008135//translation factor activity, RNA binding;GO:0005515//protein binding" GO:0006412//translation gi|74204153|dbj|BAE39841.1|/7.87558e-151/unnamed protein product [Mus musculus] 67194 1351 1 0.793333333 -0.334000927 Down 0.219254203 2700038G22Rik RIKEN cDNA 2700038G22 gene - - - - - 626802 4050 1.05 1.276666667 0.281992564 Up 0.219207191 Gm14322 predicted gene 14322 K09228|1|0.0|779|mmu:626802|KRAB domain-containing zinc finger protein - - - gi|345199290|ref|NP_001230832.1|/0/uncharacterized protein LOC626802 [Mus musculus] 69146 1776 5.246666667 4.796666667 -0.129368949 Down 0.219207191 Gsdmd gasdermin D - - - GO:0007154//cell communication gi|21312216|ref|NP_081236.1|/0/gasdermin-D [Mus musculus] 665205 1101 1.076666667 1.306666667 0.279319489 Up 0.219207191 Gm14327 predicted gene 14327 - - - - - 100316903 4513 4.813333333 5.266666667 0.129853816 Up 0.219207191 Gm20605 predicted gene 20605 K19193|1|1e-150|537|mmu:751865|histone deacetylase complex subunit SAP25 - - - - 21933 3197 4.8 5.25 0.129283017 Up 0.219207191 Tnfrsf10b "tumor necrosis factor receptor superfamily, member 10b" K04722|1|3e-177|625|mmu:21933|tumor necrosis factor receptor superfamily member 10 GO:0031224//intrinsic component of membrane GO:0005515//protein binding;GO:0016505//peptidase activator activity involved in apoptotic process GO:0097191//extrinsic apoptotic signaling pathway;GO:0034976//response to endoplasmic reticulum stress gi|31981095|ref|NP_064671.2|/2.74115e-176/tumor necrosis factor receptor superfamily member 10B precursor [Mus musculus] 327826 5701 5.1 4.65 -0.133266531 Down 0.219207191 Frs2 fibroblast growth factor receptor substrate 2 K12461|1|0.0|970|mmu:327826|fibroblast growth factor receptor substrate 2 GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane "GO:0005167;GO:0008047//enzyme activator activity;GO:0030674//protein binding, bridging;GO:0070851//growth factor receptor binding" GO:0048699//generation of neurons;GO:0042127//regulation of cell proliferation;GO:0007369//gastrulation;GO:0003156//regulation of organ formation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0060442//branching involved in prostate gland morphogenesis;GO:0007420//brain development;GO:0006468//protein phosphorylation;GO:0000578//embryonic axis specification;GO:0001743//optic placode formation;GO:0003231//cardiac ventricle development gi|29244340|ref|NP_808466.1|/0/fibroblast growth factor receptor substrate 2 [Mus musculus] 68653 1673 147.8366667 140.37 -0.074769499 Down 0.219188386 Samm50 SAMM50 sorting and assembly machinery component K07277|1|0.0|930|mmu:68653|outer membrane protein insertion porin family GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0005741//mitochondrial outer membrane GO:0005488//binding GO:0006626//protein targeting to mitochondrion gi|30519943|ref|NP_848729.1|/0/sorting and assembly machinery component 50 homolog [Mus musculus] 71913 2337 0.4 0.246666667 -0.69743723 Down 0.219169581 Tmem79 transmembrane protein 79 - GO:0031224//intrinsic component of membrane - - gi|17511437|ref|NP_077208.1|/6.76903e-174/transmembrane protein 79 [Mus musculus] 232664 3225 0.593333333 0.783333333 0.400783516 Up 0.219160179 Ccdc136 coiled-coil domain containing 136 K20478|1|2e-13|81.3|sko:100377934|golgin subfamily B member 1;K20283|5|2e-13|80.9|apla:101803359|golgin subfamily A member 4 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - "gi|148681833|gb|EDL13780.1|/0/mCG9138, isoform CRA_b, partial [Mus musculus]" 75783 2262 0.79 0.596666667 -0.404927472 Down 0.219160179 4930431F12Rik RIKEN cDNA 4930431F12 gene - - - - gi|12853539|dbj|BAB29773.1|/4.62812e-79/unnamed protein product [Mus musculus] 68271 2908 0.153333333 0.046666667 -1.716207034 Down 0.219103765 Zfp85os "zinc finger protein 85, opposite strand" - - - - - 20370 4164 0.046666667 0.153333333 1.716207034 Up 0.219103765 Sez6 seizure related gene 6 K10362|1|0.0|777|gfr:102036530|myosin XVIII;K17495|2|7e-69|265|ocu:100351291|CUB and sushi domain-containing protein GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0044424;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0044424;GO:0044421 - GO:0051899//membrane depolarization;GO:0010976//positive regulation of neuron projection development;GO:0010977//negative regulation of neuron projection development;GO:0051899//membrane depolarization;GO:0010976//positive regulation of neuron projection development;GO:0010977//negative regulation of neuron projection development gi|31981500|ref|NP_067261.2|/0/seizure protein 6 isoform 1 precursor [Mus musculus] 68386 951 0.163333333 0.05 -1.707819249 Down 0.219103765 0610039K10Rik RIKEN cDNA 0610039K10 gene - - - - gi|148674396|gb|EDL06343.1|/3.80046e-29/mCG147188 [Mus musculus] 227399 5568 15.85 14.9 -0.08917051 Down 0.219000338 Ppip5k2 diphosphoinositol pentakisphosphate kinase 2 K13024|1|0.0|2121|mmu:227399|inositol-hexakisphosphate/diphosphoinositol-pentakisphosphate 1-kinase [EC:2.7.4.24] - - - gi|37359944|dbj|BAC97950.1|/0/mKIAA0433 protein [Mus musculus] 72325 2842 15.61666667 16.56666667 0.085196804 Up 0.219000338 Vps9d1 VPS9 domain containing 1 K17638|1|2e-06|57.4|oaa:100093582|Ras and Rab interactor 1;K20131|4|5e-06|56.2|aga:AgaP_AGAP005551|Rab5 GDP/GTP exchange factor GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - - gi|893538708|ref|NP_001297590.1|/0/VPS9 domain-containing protein 1 isoform 1 [Mus musculus] 544717 741.29 15.92 14.96666667 -0.089087392 Down 0.219000338 1190007I07Rik RIKEN cDNA 1190007I07 gene - - - - gi|625206604|ref|XP_003505897.2|/6.60117e-27/PREDICTED: uncharacterized protein C12orf73 homolog isoform X2 [Cricetulus griseus] 108927 2107 25.24333333 26.72 0.08201758 Up 0.218990936 Lhfp lipoma HMGIC fusion partner K15101|1|2e-06|57.0|ecb:100069313|solute carrier family 25 (mitochondrial ornithine transporter) member 2/15 - - - gi|74197983|dbj|BAE35174.1|/1.08285e-74/unnamed protein product [Mus musculus] 14266 4486 0.103333333 0.016666667 -2.632268215 Down 0.218990936 Aff2 "AF4/FMR2 family, member 2" K15194|1|0.0|1996|mmu:14266|AF4/FMR2 family member 2 - - - gi|153792808|ref|NP_032058.2|/0/AF4/FMR2 family member 2 [Mus musculus] 232533 4617 3.073333333 2.736666667 -0.167384529 Down 0.218934522 Stk38l serine/threonine kinase 38 like K08790|1|0.0|928|mmu:232533|serine/threonine kinase 38 [EC:2.7.11.1] GO:0005856//cytoskeleton;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0008092//cytoskeletal protein binding;GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding GO:0035556//intracellular signal transduction;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0016043//cellular component organization gi|569017276|ref|XP_006536131.1|/0/PREDICTED: serine/threonine-protein kinase 38-like isoform X3 [Mus musculus] 100135657 648 0.086666667 0.01 -3.115477217 Down 0.218915717 Rhox3e reproductive homeobox 3E K18491|1|3e-10|67.4|lve:103090446|homeobox protein ESX1;K09451|2|2e-09|64.3|hgl:101715465|homeobox protein aristaless-like 4 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding - gi|73088780|ref|NP_918952.2|/8.79387e-122/reproductive homeobox 3A [Mus musculus] 14686 1796 0.01 0.086666667 3.115477217 Up 0.218915717 Gnat2 "guanine nucleotide binding protein, alpha transducing 2" K04631|1|0.0|711|mmu:14686|guanine nucleotide-binding protein G(t) subunit alpha 1/2 GO:0031234//extrinsic component of cytoplasmic side of plasma membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0043169//cation binding;GO:0032403//protein complex binding;GO:0017076//purine nucleotide binding "GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0042462//eye photoreceptor cell development;GO:0007601//visual perception;GO:0009154//purine ribonucleotide catabolic process;GO:0050906//detection of stimulus involved in sensory perception" "gi|148670000|gb|EDL01947.1|/0/mCG4057, isoform CRA_b, partial [Mus musculus]" 77668 676 0.086666667 0.01 -3.115477217 Down 0.218915717 9130209A04Rik RIKEN cDNA 9130209A04 gene - - - - - 209488 1225 0.086666667 0.01 -3.115477217 Down 0.218915717 Hsh2d hematopoietic SH2 domain containing K08834|1|1e-24|116|sko:102805349|myosin III [EC:2.7.11.1];K08273|2|2e-23|112|pss:102456679|SH2 domain protein 2A GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0030674//protein binding, bridging" GO:0001783//B cell apoptotic process;GO:0046649//lymphocyte activation;GO:0032845 gi|37537546|ref|NP_922935.1|/1.75067e-179/hematopoietic SH2 domain-containing protein [Mus musculus] 622473 679 0.086666667 0.01 -3.115477217 Down 0.218915717 Ripply1 ripply transcriptional repressor 1 - - - "GO:0006351//transcription, DNA-templated" gi|83776579|ref|NP_001033004.1|/2.36591e-59/protein ripply1 [Mus musculus] 72735 1555 0.01 0.086666667 3.115477217 Up 0.218915717 Eldr Egfr long non-coding downstream RNA - - - - - 75910 551 0.01 0.086666667 3.115477217 Up 0.218915717 4930590L20Rik RIKEN cDNA 4930590L20 gene K04947|1|9e-13|75.1|pale:102888097|potassium channel subfamily T member 2 - GO:0032550;GO:0005227//calcium activated cation channel activity - "gi|148707571|gb|EDL39518.1|/1.82386e-40/mCG146337, partial [Mus musculus]" 16867 2553 0.01 0.086666667 3.115477217 Up 0.218915717 Lhcgr luteinizing hormone/choriogonadotropin receptor K04248|1|0.0|1351|mmu:16867|luteinizing hormone/choriogonadotropin receptor GO:0000323//lytic vacuole;GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0009897//external side of plasma membrane;GO:0044421 GO:0042562//hormone binding;GO:0042802//identical protein binding;GO:0042277//peptide binding;GO:0001653//peptide receptor activity;GO:0019899//enzyme binding;GO:0016500//protein-hormone receptor activity "GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0048232//male gamete generation;GO:0009967//positive regulation of signal transduction;GO:0045762//positive regulation of adenylate cyclase activity;GO:0032870//cellular response to hormone stimulus;GO:0006623//protein targeting to vacuole;GO:0042698//ovulation cycle;GO:0007399//nervous system development;GO:0032959//inositol trisphosphate biosynthetic process;GO:0045136//development of secondary sexual characteristics;GO:0019722//calcium-mediated signaling;GO:0008584//male gonad development;GO:0050810//regulation of steroid biosynthetic process;GO:0015909//long-chain fatty acid transport" "gi|148706705|gb|EDL38652.1|/0/luteinizing hormone/choriogonadotropin receptor, partial [Mus musculus]" 20760 609 0.01 0.086666667 3.115477217 Up 0.218915717 Sprr2f small proline-rich protein 2F - GO:0043231//intracellular membrane-bounded organelle - GO:0043627//response to estrogen;GO:0009913//epidermal cell differentiation "gi|112362181|gb|AAI20759.1|/5.70166e-29/Sprr2f protein, partial [Mus musculus]" 22268 1769 0.01 0.086666667 3.115477217 Up 0.218915717 Upk1b uroplakin 1B K17347|1|1e-158|562|mmu:22268|uroplakin-1 GO:0044459;GO:0031224//intrinsic component of membrane - GO:0030154//cell differentiation gi|149060493|gb|EDM11207.1|/1.35004e-160/rCG52686 [Rattus norvegicus] 75370 1553 0.01 0.086666667 3.115477217 Up 0.218915717 4930563E18Rik RIKEN cDNA 4930563E18 gene - - - - "gi|148691043|gb|EDL22990.1|/2.98358e-52/mCG144720, partial [Mus musculus]" 69405 635 0.01 0.086666667 3.115477217 Up 0.218915717 1700019E08Rik RIKEN cDNA 1700019E08 gene - - - - "gi|148694921|gb|EDL26868.1|/5.10711e-47/mCG144755, partial [Mus musculus]" 387143 83 0.01 0.086666667 3.115477217 Up 0.218915717 Mir101a microRNA 101a - - - - - 328779 1234 0.086666667 0.01 -3.115477217 Down 0.218915717 Hs3st6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 K09679|1|3e-167|590|mmu:328779|[heparan sulfate]-glucosamine 3-sulfotransferase 6 [EC:2.8.2.-] GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0034483//heparan sulfate sulfotransferase activity GO:0006023;GO:0044238//primary metabolic process gi|60223081|ref|NP_001012402.1|/2.23656e-166/heparan sulfate glucosamine 3-O-sulfotransferase 6 [Mus musculus] 383766 639 0.01 0.086666667 3.115477217 Up 0.218915717 Tldc2 TBC/LysM associated domain containing 2 K12587|1|1e-33|144|bfo:BRAFLDRAFT_124886|exosome complex component MTR3 - - - gi|294460014|ref|NP_001170910.1|/2.16242e-109/TLD domain-containing protein 2 [Mus musculus] 77538 628 0.01 0.086666667 3.115477217 Up 0.218915717 C330004P14Rik RIKEN cDNA C330004P14 gene - - - - - 214301 614 0.01 0.086666667 3.115477217 Up 0.218915717 Crygn "crystallin, gamma N" K16810|1|1e-35|151|bacu:103015945|TBCC domain-containing protein 1;K01886|2|1e-08|61.6|ccw:104683491|glutaminyl-tRNA synthetase [EC:6.1.1.18] - GO:0005198//structural molecule activity - gi|244798550|ref|NP_694716.2|/3.54073e-111/gamma-crystallin N [Mus musculus] 100579137 675 0.086666667 0.01 -3.115477217 Down 0.218915717 Dmr Dmrt1 interacting ncRNA - - - - - 71473 639 0.086666667 0.01 -3.115477217 Down 0.218915717 8430423G03Rik RIKEN cDNA 8430423G03 gene - - - - - 108017 551 0.01 0.086666667 3.115477217 Up 0.218915717 Fxyd4 FXYD domain-containing ion transport regulator 4 K13359|1|1e-24|114|mmu:108017|FXYD domain containing ion transport regulator 4 - GO:0019899//enzyme binding;GO:0019899//enzyme binding GO:0034220//ion transmembrane transport;GO:0034220//ion transmembrane transport "gi|148667172|gb|EDK99588.1|/2.62755e-47/FXYD domain-containing ion transport regulator 4, isoform CRA_b, partial [Mus musculus]" 78349 617 0.01 0.086666667 3.115477217 Up 0.218915717 1700034K08Rik RIKEN cDNA 1700034K08 gene - - - - - 57755 1186 0.086666667 0.01 -3.115477217 Down 0.218915717 Dnajb7 DnaJ heat shock protein family (Hsp40) member B7 K09513|1|5e-139|496|mmu:57755|DnaJ homolog subfamily B member 7 - - - - 21884 661 0.086666667 0.01 -3.115477217 Down 0.218915717 Fabp9 "fatty acid binding protein 9, testis" "K08753|1|3e-44|180|cmy:102944355|fatty acid-binding protein 4, adipocyte" GO:0044424 GO:0005488//binding GO:0051234//establishment of localization;GO:0003006//developmental process involved in reproduction "gi|148673226|gb|EDL05173.1|/7.5682e-76/fatty acid binding protein 9, testis [Mus musculus]" 11804 3626.15 145.9966667 139.32 -0.067533052 Down 0.21888751 Aplp2 amyloid beta (A4) precursor-like protein 2 K08117|1|0.0|1087|mmu:11804|amyloid-like protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0004866//endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding GO:0016125//sterol metabolic process;GO:0007618//mating;GO:0030003//cellular cation homeostasis;GO:0007420//brain development;GO:0010469//regulation of receptor activity;GO:0051098//regulation of binding;GO:0043062//extracellular structure organization;GO:0050905//neuromuscular process;GO:0044708//single-organism behavior;GO:0016125//sterol metabolic process;GO:0007618//mating;GO:0030003//cellular cation homeostasis;GO:0007420//brain development;GO:0010469//regulation of receptor activity;GO:0051098//regulation of binding;GO:0043062//extracellular structure organization;GO:0050905//neuromuscular process;GO:0044708//single-organism behavior;GO:0016125//sterol metabolic process;GO:0007618//mating;GO:0030003//cellular cation homeostasis;GO:0007420//brain development;GO:0010469//regulation of receptor activity;GO:0051098//regulation of binding;GO:0043062//extracellular structure organization;GO:0050905//neuromuscular process;GO:0044708//single-organism behavior gi|74211706|dbj|BAE29207.1|/0/unnamed protein product [Mus musculus] 22033 2249 1.926666667 1.653333333 -0.220729372 Down 0.218765279 Traf5 TNF receptor-associated factor 5 K09849|1|0.0|1151|mmu:22033|TNF receptor-associated factor 5 GO:0005815//microtubule organizing center;GO:0005887//integral component of plasma membrane GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0060089;GO:0019787//ubiquitin-like protein transferase activity GO:0008283//cell proliferation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0032446//protein modification by small protein conjugation gi|485464594|ref|NP_035763.2|/0/TNF receptor-associated factor 5 [Mus musculus] 68127 1189 0.173333333 0.313333333 0.854149134 Up 0.218765279 B230217C12Rik RIKEN cDNA B230217C12 gene - - - - gi|124286858|ref|NP_001074404.1|/3.70759e-78/uncharacterized protein LOC68127 [Mus musculus] 100043609 979 1.893333333 1.623333333 -0.221969157 Down 0.218765279 Gm14207 predicted gene 14207 - - - - - 67267 473 144.15 137.6766667 -0.066286763 Down 0.218727669 Uqcc2 ubiquinol-cytochrome c reductase complex assembly factor 2 K17682|1|1e-75|283|mmu:67267|mitochondrial nucleoid factor 1 GO:0005759//mitochondrial matrix - - gi|13385560|ref|NP_080339.1|/9.98621e-75/ubiquinol-cytochrome-c reductase complex assembly factor 2 [Mus musculus] 433100 3867 0.423333333 0.596666667 0.49513109 Up 0.218718267 AA388235 expressed sequence AA388235 - - - - gi|148675524|gb|EDL07471.1|/4.60042e-56/mCG147212 [Mus musculus] 17259 1339 0.41 0.58 0.500428991 Up 0.218718267 Mef2b myocyte enhancer factor 2B K09261|1|2e-165|584|mmu:17259|MADS-box transcription enhancer factor 2B GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0019899//enzyme binding "GO:0006351//transcription, DNA-templated" gi|113865987|ref|NP_001038949.1|/1.80883e-164/myocyte-specific enhancer factor 2B [Mus musculus] 170791 2813.97 25.42666667 26.89 0.080727412 Up 0.218718267 Rbm39 RNA binding motif protein 39 K13091|1|0.0|726|rno:362251|RNA-binding protein 39 GO:0005815//microtubule organizing center;GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0005654//nucleoplasm GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding "GO:0006396//RNA processing;GO:0006351//transcription, DNA-templated;GO:0006396//RNA processing;GO:0006351//transcription, DNA-templated;GO:0006396//RNA processing;GO:0006351//transcription, DNA-templated" gi|537151504|gb|ERE71699.1|/0/RNA-binding protein 39-like isoform 2 [Cricetulus griseus] 382090 5295 0.406666667 0.573333333 0.495527417 Up 0.218718267 Cep162 centrosomal protein 162 K16809|1|0.0|2501|mmu:382090|protein QN1 GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle - GO:0000087//mitotic M phase gi|147905039|ref|NP_955020.2|/0/centrosomal protein of 162 kDa [Mus musculus] 23831 1625 134.4566667 128.0266667 -0.070696949 Down 0.218708865 Car14 carbonic anhydrase 14 K01672|1|0.0|649|mmu:23831|carbonic anhydrase [EC:4.2.1.1] GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0003824//catalytic activity - gi|568922714|ref|XP_006501505.1|/0/PREDICTED: carbonic anhydrase 14 isoform X1 [Mus musculus] 15160 2204 0.05 0.156666667 1.647698256 Up 0.218680657 Serpind1 "serine (or cysteine) peptidase inhibitor, clade D, member 1" K03912|1|0.0|901|mmu:15160|heparin cofactor II - - - gi|161377465|ref|NP_032249.3|/0/heparin cofactor 2 precursor [Mus musculus] 240261 2818 0.053333333 0.166666667 1.64385619 Up 0.218680657 Ccdc112 coiled-coil domain containing 112 - - - - gi|237874229|ref|NP_001153871.1|/0/coiled-coil domain-containing protein 112 precursor [Mus musculus] 54563 7043 0.51 0.69 0.436099115 Up 0.218661853 Nup210 nucleoporin 210 K14314|1|0.0|3549|mmu:54563|nuclear pore complex protein Nup210 GO:0005635//nuclear envelope;GO:0031090//organelle membrane GO:0005515//protein binding;GO:0005198//structural molecule activity GO:0050658//RNA transport;GO:0045184//establishment of protein localization gi|172073152|ref|NP_061285.2|/0/nuclear pore membrane glycoprotein 210 precursor [Mus musculus] 229725 2147.4 15.47333333 16.41666667 0.085377202 Up 0.21865245 Clcc1 chloride channel CLIC-like 1 K04993|1|3e-37|159|xma:102221375|mucolipin 2 GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0005253//anion channel activity;GO:0005253//anion channel activity;GO:0005253//anion channel activity GO:0015698//inorganic anion transport;GO:0015698//inorganic anion transport;GO:0015698//inorganic anion transport "gi|148670033|gb|EDL01980.1|/0/chloride channel CLIC-like 1, isoform CRA_c, partial [Mus musculus]" 224902 3299 15.09 16.03 0.08718162 Up 0.21865245 Safb2 scaffold attachment factor B2 K05090|1|5e-63|245|ocu:100340992|macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1];K00753|2|7e-35|143|pxy:105390580|glycoprotein 3-alpha-L-fucosyltransferase [EC:2.4.1.214];K14946|4|1e-08|65.5|cbr:CBG20166|RNA binding protein fox-1 - - - gi|569000048|ref|XP_006524220.1|/0/PREDICTED: scaffold attachment factor B2 isoform X2 [Mus musculus] 14697 2226.08 15.67 14.73 -0.089247749 Down 0.21865245 Gnb5 "guanine nucleotide binding protein (G protein), beta 5" K04539|1|0.0|657|pale:102881664|guanine nucleotide-binding protein subunit beta-5 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0044444//cytoplasmic part GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0060089;GO:0005515//protein binding GO:0009154//purine ribonucleotide catabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0009154//purine ribonucleotide catabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0009154//purine ribonucleotide catabolic process;GO:0007166//cell surface receptor signaling pathway gi|6754018|ref|NP_034443.1|/0/guanine nucleotide-binding protein subunit beta-5 isoform 1 [Mus musculus] 68833 1706 28.05666667 26.61 -0.076375106 Down 0.218614841 Pdcl3 phosducin-like 3 K08327|1|3e-08|62.8|gfr:102040898|phosducin GO:0044424 - GO:0012501//programmed cell death gi|31560120|ref|NP_081126.2|/2.15902e-99/phosducin-like protein 3 [Mus musculus] 76916 2080 27.09 28.53666667 0.075056432 Up 0.218614841 Timmdc1 translocase of inner mitochondrial membrane domain containing 1 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - "gi|225543444|ref|NP_077235.2|/5.00059e-157/complex I assembly factor TIMMDC1, mitochondrial [Mus musculus]" 224903 3183 26.13 27.57666667 0.077740957 Up 0.218614841 Safb scaffold attachment factor B K05090|1|3e-70|269|ocu:100340992|macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1];K00753|2|2e-37|160|pxy:105390580|glycoprotein 3-alpha-L-fucosyltransferase [EC:2.4.1.214];K12888|3|8e-08|62.4|xla:399374|heterogeneous nuclear ribonucleoprotein U;K14573|4|3e-07|60.5|dan:Dana_GF11912|nucleolar protein 4;K12897|5|4e-07|60.1|aga:AgaP_AGAP013051|transformer-2 protein GO:0031981//nuclear lumen GO:0019900//kinase binding;GO:0044212//transcription regulatory region DNA binding GO:0006397//mRNA processing;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter gi|254028159|ref|NP_001156772.1|/0/scaffold attachment factor B1 [Mus musculus] 100126824 1158 26.42 24.96666667 -0.081627249 Down 0.218614841 Sco2 SCO2 cytochrome c oxidase assembly protein K07152|1|3e-136|487|mmu:100126824|protein SCO1/2 GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0046914//transition metal ion binding GO:0050896//response to stimulus;GO:0022900//electron transport chain;GO:0003008;GO:0000041//transition metal ion transport;GO:0043623//cellular protein complex assembly;GO:0030003//cellular cation homeostasis gi|672060036|ref|XP_008763952.1|/2.04306e-170/PREDICTED: thymidine phosphorylase isoform X1 [Rattus norvegicus] 67241 5603 3.15 3.51 0.156119202 Up 0.218605438 Smc6 structural maintenance of chromosomes 6 K20478|1|2e-21|108|dre:557772|golgin subfamily B member 1 GO:0044427;GO:0016604//nuclear body;GO:0000793//condensed chromosome;GO:0044427;GO:0016604//nuclear body;GO:0000793//condensed chromosome GO:0032550;GO:0032550 GO:0000723//telomere maintenance;GO:0033554//cellular response to stress;GO:0007569//cell aging;GO:0000723//telomere maintenance;GO:0033554//cellular response to stress;GO:0007569//cell aging gi|60360136|dbj|BAD90287.1|/0/mKIAA4103 protein [Mus musculus] 320415 629 3.046666667 3.41 0.162540075 Up 0.218605438 Gchfr GTP cyclohydrolase I feedback regulator - GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0005635//nuclear envelope;GO:0048770 GO:0019899//enzyme binding;GO:0031406//carboxylic acid binding;GO:0003824//catalytic activity GO:0051259//protein oligomerization;GO:0043095//regulation of GTP cyclohydrolase I activity;GO:0006809//nitric oxide biosynthetic process gi|28893139|ref|NP_796131.1|/9.86019e-43/GTP cyclohydrolase 1 feedback regulatory protein [Mus musculus] 75717 5942 5.743333333 6.246666667 0.121198251 Up 0.218558426 Cul5 cullin 5 K10612|1|0.0|1589|mmu:75717|cullin 5 GO:0043231//intracellular membrane-bounded organelle;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0016020//membrane GO:0008528//G-protein coupled peptide receptor activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0008528//G-protein coupled peptide receptor activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity GO:0019941//modification-dependent protein catabolic process;GO:0006874//cellular calcium ion homeostasis;GO:0006950//response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0006874//cellular calcium ion homeostasis;GO:0006950//response to stress gi|239051067|ref|NP_082083.2|/0/cullin-5 isoform 1 [Mus musculus] 68070 13413 5.68 6.176666667 0.120937546 Up 0.218558426 Pdzd2 PDZ domain containing 2 K06095|1|2e-33|149|lcm:102360592|multiple PDZ domain protein GO:0044327//dendritic spine head;GO:0030054//cell junction;GO:0043231//intracellular membrane-bounded organelle - GO:0007165//signal transduction;GO:0022610 gi|124486716|ref|NP_001074533.1|/0/PDZ domain-containing protein 2 [Mus musculus] 66583 1622 5.926666667 6.43 0.117597819 Up 0.218558426 Exosc1 exosome component 1 K07573|1|1e-107|392|mmu:66583|exosome complex component CSL4 GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0005488//binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0042254//ribosome biogenesis;GO:0010467//gene expression;GO:0010467//gene expression;GO:0042254//ribosome biogenesis;GO:0010467//gene expression;GO:0042254//ribosome biogenesis;GO:0010467//gene expression;GO:0042254//ribosome biogenesis;GO:0010467//gene expression gi|742089254|ref|XP_010831354.1|/1.18484e-107/PREDICTED: exosome complex component CSL4 isoform X1 [Bison bison bison] 70693 4475 6.006666667 5.51 -0.124512287 Down 0.218558426 Adgra3 adhesion G protein-coupled receptor A3 K08462|1|0.0|2421|mmu:70693|G protein-coupled receptor 125 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007186//G-protein coupled receptor signaling pathway "gi|30851397|gb|AAH52391.1|/0/Gpr125 protein, partial [Mus musculus]" 71564 938 1.766666667 1.506666667 -0.229669587 Down 0.218539622 Izumo4 IZUMO family member 4 - - - - gi|89886473|ref|NP_082105.3|/1.7883e-132/izumo sperm-egg fusion protein 4 precursor [Mus musculus] 100306945 205 1.743333333 1.486666667 -0.229767236 Down 0.218539622 Snora73b "small nucleolar RNA, H/ACA box 73b" K17585|1|2e-14|70.1|lve:103088203|phosphatase and actin regulator 4 - - - gi|602699793|ref|XP_007461897.1|/1.52918e-13/PREDICTED: phosphatase and actin regulator 4 [Lipotes vexillifer] 21745 8163 1.746666667 1.486666667 -0.232523102 Down 0.218539622 Tep1 telomerase associated protein 1 K11127|1|0.0|4957|mmu:21745|telomerase protein component 1 GO:0044427;GO:0034399//nuclear periphery;GO:0030529//intracellular ribonucleoprotein complex GO:0032550;GO:0003676//nucleic acid binding;GO:0003964//RNA-directed DNA polymerase activity GO:0006278//RNA-dependent DNA biosynthetic process;GO:0000723//telomere maintenance gi|6678285|ref|NP_033377.1|/0/telomerase protein component 1 [Mus musculus] 114863 3580.6 24.71333333 26.15666667 0.081889085 Up 0.218473805 Prosc proline synthetase co-transcribed K06997|1|1e-150|536|mmu:114863|PLP dependent protein - - - gi|16930823|ref|NP_473398.1|/1.12933e-149/proline synthase co-transcribed bacterial homolog protein isoform a [Mus musculus] 74724 1421 0.25 0.4 0.678071905 Up 0.218398586 4930512B01Rik RIKEN cDNA 4930512B01 gene K08833|1|5e-20|101|mmu:399510|mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1] GO:0044424;GO:0016020//membrane GO:0032550;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity GO:0035556//intracellular signal transduction;GO:0006464//cellular protein modification process "gi|148704651|gb|EDL36598.1|/2.33243e-24/mCG1041621, isoform CRA_b [Mus musculus]" 73711 1077 24.53333333 25.96666667 0.081917562 Up 0.218351574 Mvb12a multivesicular body subunit 12A K12186|1|4e-145|516|mmu:73711|ESCRT-I complex subunit MVB12 GO:0005770//late endosome;GO:0016234//inclusion body;GO:0031981//nuclear lumen;GO:0015630//microtubule cytoskeleton GO:0019904//protein domain specific binding GO:0045184//establishment of protein localization gi|21312058|ref|NP_082893.1|/3.32642e-144/multivesicular body subunit 12A [Mus musculus] 231798 3081 15.52666667 14.59666667 -0.08910919 Down 0.218266952 Lrch4 leucine-rich repeats and calponin homology (CH) domain containing 4 K10130|1|3e-24|114|bom:102281142|leucine-rich repeats and death domain-containing protein GO:0016604//nuclear body;GO:0016604//nuclear body - "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|22122701|ref|NP_666276.1|/0/leucine-rich repeat and calponin homology domain-containing protein 4 isoform 1 [Mus musculus] 102122 1812 14.56 15.49333333 0.089637212 Up 0.218266952 Fam192a "family with sequence similarity 192, member A" - GO:0043231//intracellular membrane-bounded organelle - - gi|20072546|gb|AAH27060.1|/2.12039e-92/RIKEN cDNA 2310065K24 gene [Mus musculus] 72479 2635.71 118.55 112.71 -0.072880141 Down 0.21825755 Hsdl2 hydroxysteroid dehydrogenase like 2 "K12405|1|3e-13|80.1|xma:102223774|3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.35 4.2.1.107 4.2.1.119]" GO:0042579//microbody;GO:0042579//microbody GO:0036094//small molecule binding;GO:0003824//catalytic activity;GO:0005496//steroid binding;GO:0036094//small molecule binding;GO:0003824//catalytic activity;GO:0005496//steroid binding GO:0044710;GO:0044710 "gi|148670259|gb|EDL02206.1|/1.39107e-133/hydroxysteroid dehydrogenase like 2, isoform CRA_b, partial [Mus musculus]" 18647 4928 1.623333333 1.37 -0.244783378 Down 0.218229343 Cdk14 cyclin-dependent kinase 14 K08821|1|0.0|929|mmu:18647|cyclin-dependent kinase 14 [EC:2.7.11.22] GO:0043231//intracellular membrane-bounded organelle;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding GO:0044772//mitotic cell cycle phase transition;GO:0030111//regulation of Wnt signaling pathway gi|161086911|ref|NP_035204.2|/0/cyclin-dependent kinase 14 isoform 1 [Mus musculus] 230075 682 121.7566667 127.5733333 0.067326026 Up 0.218229343 Ndufb6 "NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6" K03962|1|3e-61|236|mmu:230075|NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6 - - - - 73571 1463 1.39 1.636666667 0.235675641 Up 0.218229343 1700096K18Rik RIKEN cDNA 1700096K18 gene - - - - - 11669 2766.84 119.8866667 125.6733333 0.06800734 Up 0.218201136 Aldh2 "aldehyde dehydrogenase 2, mitochondrial" K00128|1|0.0|957|mmu:11669|aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] GO:0044429;GO:0044429 "GO:0043168//anion binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0005515//protein binding;GO:0043168//anion binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0005515//protein binding" GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0070542//response to fatty acid;GO:0006067//ethanol metabolic process;GO:0002237//response to molecule of bacterial origin;GO:0006950//response to stress;GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0070542//response to fatty acid;GO:0006067//ethanol metabolic process;GO:0002237//response to molecule of bacterial origin;GO:0006950//response to stress "gi|148687772|gb|EDL19719.1|/0/aldehyde dehydrogenase 2, mitochondrial, isoform CRA_a, partial [Mus musculus]" 67836 1238 24.77 23.36 -0.084553594 Down 0.217947271 Wdr83 WD repeat domain containing 83 K13124|1|0.0|637|mmu:67836|mitogen-activated protein kinase organizer 1 - - - - 107392 1396 14.39666667 15.32 0.089681481 Up 0.217890857 Brms1 breast cancer metastasis-suppressor 1 K19196|1|4e-106|387|mmu:107392|breast cancer metastasis-suppressor 1 and related proteins GO:0043231//intracellular membrane-bounded organelle GO:0008134//transcription factor binding GO:0031401//positive regulation of protein modification process;GO:0043065//positive regulation of apoptotic process;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity gi|569005529|ref|XP_006531686.1|/7.67181e-119/PREDICTED: breast cancer metastasis-suppressor 1 homolog isoform X3 [Mus musculus] 100038464 1673 113.1333333 118.54 0.067349898 Up 0.21786265 Gm15441 predicted gene 15441 - - - - - 74194 2827 5.16 4.72 -0.128584206 Down 0.217853248 Rnd3 Rho family GTPase 3 K07859|1|5e-129|464|ecb:100050088|Rho family GTPase 3 GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0022610;GO:0007010//cytoskeleton organization gi|724851156|ref|XP_010366888.1|/4.11831e-128/PREDICTED: rho-related GTP-binding protein RhoE [Rhinopithecus roxellana] 387524 2610 4.51 4.95 0.134301092 Up 0.217853248 Znrf2 zinc and ring finger 2 K10694|1|2e-67|260|mmu:387524|E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27] GO:0016020//membrane;GO:0000323//lytic vacuole GO:0046914//transition metal ion binding;GO:0003824//catalytic activity - "gi|148666296|gb|EDK98712.1|/1.40404e-66/zinc and ring finger 2, isoform CRA_b, partial [Mus musculus]" 70387 3470 4.48 4.916666667 0.134181816 Up 0.217853248 Ttc9c tetratricopeptide repeat domain 9C K09571|1|1e-12|78.6|mze:101485455|FK506-binding protein 4/5 [EC:5.2.1.8] - - - gi|110625776|ref|NP_081688.2|/9.93406e-79/tetratricopeptide repeat protein 9C [Mus musculus] 11549 3729.08 4.663333333 5.103333333 0.13007832 Up 0.217853248 Adra1a "adrenergic receptor, alpha 1a" K04135|1|0.0|896|mmu:11549|adrenergic receptor alpha-1A GO:0031674//I band;GO:0042383//sarcolemma;GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope;GO:0031674//I band;GO:0042383//sarcolemma;GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0031674//I band;GO:0042383//sarcolemma;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0031674//I band;GO:0042383//sarcolemma;GO:0005635//nuclear envelope GO:0046983//protein dimerization activity;GO:0004936//alpha-adrenergic receptor activity;GO:0046983//protein dimerization activity;GO:0004936//alpha-adrenergic receptor activity;GO:0046983//protein dimerization activity;GO:0004936//alpha-adrenergic receptor activity;GO:0046983//protein dimerization activity;GO:0004936//alpha-adrenergic receptor activity "GO:0003321;GO:0007186//G-protein coupled receptor signaling pathway;GO:0002027//regulation of heart rate;GO:0042221//response to chemical;GO:0007266//Rho protein signal transduction;GO:0045989//positive regulation of striated muscle contraction;GO:0001508//action potential;GO:0040007//growth;GO:0007507//heart development;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0003014//renal system process;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0001983;GO:0019229//regulation of vasoconstriction;GO:0010863//positive regulation of phospholipase C activity;GO:0060004//reflex;GO:0009719;GO:0006939//smooth muscle contraction;GO:0043410//positive regulation of MAPK cascade;GO:0003099//positive regulation of the force of heart contraction by chemical signal;GO:0003321;GO:0007186//G-protein coupled receptor signaling pathway;GO:0002027//regulation of heart rate;GO:0042221//response to chemical;GO:0007266//Rho protein signal transduction;GO:0045989//positive regulation of striated muscle contraction;GO:0001508//action potential;GO:0040007//growth;GO:0007507//heart development;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0003014//renal system process;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0001983;GO:0019229//regulation of vasoconstriction;GO:0010863//positive regulation of phospholipase C activity;GO:0060004//reflex;GO:0009719;GO:0006939//smooth muscle contraction;GO:0043410//positive regulation of MAPK cascade;GO:0003099//positive regulation of the force of heart contraction by chemical signal;GO:0003321;GO:0007186//G-protein coupled receptor signaling pathway;GO:0002027//regulation of heart rate;GO:0042221//response to chemical;GO:0007266//Rho protein signal transduction;GO:0045989//positive regulation of striated muscle contraction;GO:0001508//action potential;GO:0040007//growth;GO:0012501//programmed cell death;GO:0007507//heart development;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0003014//renal system process;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0008283//cell proliferation;GO:0001983;GO:0019229//regulation of vasoconstriction;GO:0010863//positive regulation of phospholipase C activity;GO:0060004//reflex;GO:0009719;GO:0006939//smooth muscle contraction;GO:0043410//positive regulation of MAPK cascade;GO:0003099//positive regulation of the force of heart contraction by chemical signal;GO:0003321;GO:0007186//G-protein coupled receptor signaling pathway;GO:0002027//regulation of heart rate;GO:0042221//response to chemical;GO:0007266//Rho protein signal transduction;GO:0045989//positive regulation of striated muscle contraction;GO:0001508//action potential;GO:0040007//growth;GO:0012501//programmed cell death;GO:0007507//heart development;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0003014//renal system process;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0008283//cell proliferation;GO:0001983;GO:0019229//regulation of vasoconstriction;GO:0010863//positive regulation of phospholipase C activity;GO:0060004//reflex;GO:0009719;GO:0006939//smooth muscle contraction;GO:0043410//positive regulation of MAPK cascade;GO:0003099//positive regulation of the force of heart contraction by chemical signal" gi|31542114|ref|NP_038489.2|/0/alpha-1A adrenergic receptor isoform 1 [Mus musculus] 30952 4708 0.71 0.526666667 -0.430928872 Down 0.217853248 Cngb3 cyclic nucleotide gated channel beta 3 K04953|1|0.0|1318|mmu:30952|cyclic nucleotide gated channel beta 3 GO:0031224//intrinsic component of membrane;GO:0031513//nonmotile primary cilium GO:0030551//cyclic nucleotide binding;GO:0005221//intracellular cyclic nucleotide activated cation channel activity GO:0044763;GO:0050953//sensory perception of light stimulus;GO:0009117//nucleotide metabolic process;GO:0006811//ion transport gi|8393164|ref|NP_038955.1|/0/cyclic nucleotide-gated cation channel beta-3 [Mus musculus] 75137 8419 4.933333333 4.496666667 -0.133706828 Down 0.217853248 Rprd2 regulation of nuclear pre-mRNA domain containing 2 "K15559|1|6e-21|107|xla:446428|regulator of Ty1 transposition protein 103;K14695|5|4e-20|104|dre:560642|solute carrier family 30 (zinc transporter), member 8" GO:0044451 - - gi|124486841|ref|NP_001074762.1|/0/regulation of nuclear pre-mRNA domain-containing protein 2 [Mus musculus] 18002 602 116.12 121.5 0.065339837 Up 0.217843845 Nedd8 "neural precursor cell expressed, developmentally down-regulated gene 8" K12158|1|5e-21|102|pale:102893164|ubiquitin-like protein Nedd8 GO:0043231//intracellular membrane-bounded organelle GO:0044389//ubiquitin-like protein ligase binding GO:0032446//protein modification by small protein conjugation;GO:0019941//modification-dependent protein catabolic process;GO:0033036;GO:0032502//developmental process;GO:0010033//response to organic substance;GO:0006366//transcription from RNA polymerase II promoter "gi|149063993|gb|EDM14263.1|/3.09476e-24/neural precursor cell expressed, developmentally down-regulated gene 8, isoform CRA_b [Rattus norvegicus]" 98828 1623 25.47333333 26.87 0.077008564 Up 0.217834443 Cdc123 cell division cycle 123 - GO:0044424 - GO:0044763 gi|19527052|ref|NP_598598.1|/0/cell division cycle protein 123 homolog [Mus musculus] 69894 1731 0.746666667 0.95 0.347463187 Up 0.217731017 2010107G23Rik RIKEN cDNA 2010107G23 gene "K03847|1|2e-06|57.0|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - gi|884927169|ref|XP_013012513.1|/1.90624e-18/PREDICTED: uncharacterized protein C10orf35 homolog isoform X1 [Cavia porcellus] 68040 1991 2.433333333 2.756666667 0.179990865 Up 0.217712212 Zfp593 zinc finger protein 593 K14821|1|1e-56|223|mmu:68040|bud site selection protein 20 GO:0031981//nuclear lumen GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0006366//transcription from RNA polymerase II promoter "gi|148698076|gb|EDL30023.1|/3.20998e-63/mCG146030, isoform CRA_b, partial [Mus musculus]" 338523 9553 2.353333333 2.673333333 0.183934053 Up 0.217712212 Kdm7a lysine (K)-specific demethylase 7A K11445|1|0.0|1731|mmu:338523|lysine-specific demethylase 7A [EC:1.14.11.-] GO:0031981//nuclear lumen "GO:0032452//histone demethylase activity;GO:0042393//histone binding;GO:0046914//transition metal ion binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" "GO:0007420//brain development;GO:0070076//histone lysine demethylation;GO:0006351//transcription, DNA-templated" gi|157909789|ref|NP_001028602.2|/0/lysine-specific demethylase 7A [Mus musculus] 17540 6057.2 2.773333333 2.45 -0.178839278 Down 0.217712212 Mrvi1 MRV integration site 1 "K12337|1|0.0|1411|mmu:17540|inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate" GO:0005783//endoplasmic reticulum;GO:0031224//intrinsic component of membrane;GO:0005783//endoplasmic reticulum;GO:0031224//intrinsic component of membrane - - gi|154275769|ref|NP_034956.2|/0/protein MRVI1 isoform a [Mus musculus] 17777 3962 2.663333333 2.343333333 -0.184670814 Down 0.217712212 Mttp microsomal triglyceride transfer protein K14463|1|0.0|1736|mmu:17777|microsomal triglyceride transfer protein large subunit GO:0005903//brush border;GO:0044459;GO:0031982//vesicle;GO:0005902//microvillus;GO:0005783//endoplasmic reticulum GO:0022892//substrate-specific transporter activity;GO:0046983//protein dimerization activity GO:0055092//sterol homeostasis;GO:0010038//response to metal ion;GO:0006464//cellular protein modification process;GO:0016125//sterol metabolic process;GO:0010876//lipid localization;GO:0006639//acylglycerol metabolic process;GO:0015031//protein transport gi|254540223|ref|NP_032668.2|/0/microsomal triglyceride transfer protein large subunit isoform 2 precursor [Mus musculus] 14816 7007 7.596666667 7.023333333 -0.11321061 Down 0.217674602 Grm1 "glutamate receptor, metabotropic 1" K04603|1|0.0|1761|myb:102262360|metabotropic glutamate receptor 1 GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0031224//intrinsic component of membrane GO:0035258//steroid hormone receptor binding;GO:0008066//glutamate receptor activity;GO:0035258//steroid hormone receptor binding;GO:0008066//glutamate receptor activity "GO:0051602//response to electrical stimulus;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0010646//regulation of cell communication;GO:0035249//synaptic transmission, glutamatergic;GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade;GO:0019233//sensory perception of pain;GO:0019932//second-messenger-mediated signaling;GO:0042391//regulation of membrane potential;GO:0044708//single-organism behavior;GO:0051602//response to electrical stimulus;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0035249//synaptic transmission, glutamatergic;GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade;GO:0019233//sensory perception of pain;GO:0019932//second-messenger-mediated signaling;GO:0044708//single-organism behavior" gi|166999785|ref|NP_001107805.1|/0/metabotropic glutamate receptor 1 isoform beta precursor [Mus musculus] 238276 6685 0.5 0.34 -0.556393349 Down 0.2176652 Akap5 A kinase (PRKA) anchor protein 5 K16522|1|0.0|1391|mmu:238276|A-kinase anchor protein 5 - - - gi|568979596|ref|XP_006515905.1|/0/PREDICTED: A-kinase anchor protein 5 isoform X1 [Mus musculus] 21743 1023 6.326666667 5.836666667 -0.116300909 Down 0.217636993 Inmt indolethylamine N-methyltransferase K00562|1|1e-136|488|mmu:21743|methyltransferase [EC:2.1.1.49 2.1.1.96] GO:0044444//cytoplasmic part GO:0008172//S-methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity GO:1901564;GO:0042221//response to chemical gi|6678281|ref|NP_033375.1|/8.95785e-136/indolethylamine N-methyltransferase [Mus musculus] 620695 1291 5.436666667 5.923333333 0.123686899 Up 0.217636993 Gm13889 predicted gene 13889 - - - - gi|190356058|sp|Q3UPL5.2|CK096_MOUSE/7.83516e-55/RecName: Full=Uncharacterized protein C11orf96 homolog; AltName: Full=Protein Ag2 homolog 15451 1806 1.133333333 1.363333333 0.266566097 Up 0.217599383 Hpn hepsin K08665|1|0.0|857|mmu:15451|hepsin [EC:3.4.21.106] GO:0031090//organelle membrane;GO:0030054//cell junction;GO:0016021//integral component of membrane;GO:0005635//nuclear envelope;GO:0044297//cell body;GO:0031090//organelle membrane;GO:0030054//cell junction;GO:0016021//integral component of membrane;GO:0005635//nuclear envelope;GO:0044297//cell body;GO:0031090//organelle membrane;GO:0030054//cell junction;GO:0016021//integral component of membrane;GO:0005635//nuclear envelope;GO:0044297//cell body GO:0038024//cargo receptor activity;GO:0005227//calcium activated cation channel activity;GO:0008236//serine-type peptidase activity;GO:0004175//endopeptidase activity;GO:0038024//cargo receptor activity;GO:0005227//calcium activated cation channel activity;GO:0008236//serine-type peptidase activity;GO:0004175//endopeptidase activity;GO:0038024//cargo receptor activity;GO:0005227//calcium activated cation channel activity;GO:0008236//serine-type peptidase activity;GO:0004175//endopeptidase activity GO:0006915//apoptotic process;GO:0006590//thyroid hormone generation;GO:0016049//cell growth;GO:0050679//positive regulation of epithelial cell proliferation;GO:0001837//epithelial to mesenchymal transition;GO:0050877//neurological system process;GO:0043921;GO:0034220//ion transmembrane transport;GO:0022617//extracellular matrix disassembly;GO:0008285//negative regulation of cell proliferation;GO:0060004//reflex;GO:0022604//regulation of cell morphogenesis;GO:0010755//regulation of plasminogen activation;GO:0048598//embryonic morphogenesis;GO:0009725//response to hormone;GO:0006915//apoptotic process;GO:0006590//thyroid hormone generation;GO:0016049//cell growth;GO:0050679//positive regulation of epithelial cell proliferation;GO:0001837//epithelial to mesenchymal transition;GO:0050877//neurological system process;GO:0043921;GO:0034220//ion transmembrane transport;GO:0022617//extracellular matrix disassembly;GO:0008285//negative regulation of cell proliferation;GO:0060004//reflex;GO:0022604//regulation of cell morphogenesis;GO:0010755//regulation of plasminogen activation;GO:0048598//embryonic morphogenesis;GO:0009725//response to hormone;GO:0006915//apoptotic process;GO:0006590//thyroid hormone generation;GO:0016049//cell growth;GO:0050679//positive regulation of epithelial cell proliferation;GO:0001837//epithelial to mesenchymal transition;GO:0050877//neurological system process;GO:0043921;GO:0034220//ion transmembrane transport;GO:0022617//extracellular matrix disassembly;GO:0008285//negative regulation of cell proliferation;GO:0060004//reflex;GO:0022604//regulation of cell morphogenesis;GO:0010755//regulation of plasminogen activation;GO:0048598//embryonic morphogenesis;GO:0009725//response to hormone gi|159110512|ref|NP_001103722.1|/0/serine protease hepsin isoform 1 precursor [Mus musculus] 71955 2352 24.49333333 25.88 0.079448492 Up 0.217589981 Ist1 increased sodium tolerance 1 homolog (yeast) K19476|1|2e-160|568|mmu:71955|vacuolar protein sorting-associated protein IST1 GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0044444//cytoplasmic part GO:0019904//protein domain specific binding GO:0033036;GO:0030307//positive regulation of cell growth;GO:0007275//multicellular organism development;GO:0046745//viral capsid secondary envelopment;GO:0006508//proteolysis;GO:0000910//cytokinesis "gi|148679481|gb|EDL11428.1|/7.14561e-164/RIKEN cDNA 2400003C14, isoform CRA_a [Mus musculus]" 67838 1826.94 24.28 25.67333333 0.080502201 Up 0.217589981 Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 K09517|1|0.0|688|pps:100992108|DnaJ homolog subfamily B member 11 - - - - 14897 9632 9.996666667 9.323333333 -0.100601268 Down 0.217505359 Trip12 thyroid hormone receptor interactor 12 K10590|1|0.0|3535|mmu:14897|E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26] GO:0031981//nuclear lumen GO:0019787//ubiquitin-like protein transferase activity;GO:0008134//transcription factor binding GO:0007275//multicellular organism development;GO:0006302//double-strand break repair;GO:0033183 gi|91932791|ref|NP_598736.4|/0/E3 ubiquitin-protein ligase TRIP12 [Mus musculus] 70382 1787 9.53 10.2 0.098021033 Up 0.217505359 Kctd2 potassium channel tetramerisation domain containing 2 K01011|1|1e-51|206|fch:102052071|thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] - - - "gi|989946546|ref|XP_015445096.1|/4.33349e-98/PREDICTED: BTB/POZ domain-containing protein KCTD2, partial [Pteropus alecto]" 105975 2976 0.213333333 0.096666667 -1.142019005 Down 0.21746775 AU022754 expressed sequence AU022754 - - - - - 381463 2661 0.096666667 0.213333333 1.142019005 Up 0.21746775 Nr1h5 "nuclear receptor subfamily 1, group H, member 5" K08538|1|0.0|1023|mmu:381463|farnesoid X receptor beta GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0038023//signaling receptor activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0038023//signaling receptor activity;GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0038023//signaling receptor activity "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|170650690|ref|NP_963916.2|/0/nuclear receptor subfamily 1, group H, member 5 isoform 5 [Mus musculus]" 19094 2452 2.103333333 1.823333333 -0.206099172 Down 0.217411336 Mapk11 mitogen-activated protein kinase 11 K04441|1|0.0|700|mmu:19094|p38 MAP kinase [EC:2.7.11.24] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550 "GO:0006355//regulation of transcription, DNA-templated;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade;GO:0042692//muscle cell differentiation" gi|168693637|ref|NP_035291.4|/0/mitogen-activated protein kinase 11 [Mus musculus] 66910 1056 1.78 2.056666667 0.208430747 Up 0.217411336 Tmem107 transmembrane protein 107 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0003002//regionalization;GO:0010927;GO:0030326//embryonic limb morphogenesis;GO:0003002//regionalization;GO:0010927;GO:0030326//embryonic limb morphogenesis "gi|148678529|gb|EDL10476.1|/1.39077e-81/RIKEN cDNA 1110004B13, isoform CRA_b, partial [Mus musculus]" 22029 3833 0.416666667 0.263333333 -0.662003536 Down 0.217401933 Traf1 TNF receptor-associated factor 1 K03172|1|0.0|798|mmu:22029|TNF receptor-associated factor 1 - - - - 214952 2825 97.99666667 93.08 -0.074261466 Down 0.217373726 Rhot2 ras homolog family member T2 "K07871|1|0.0|1207|mmu:214952|Ras homolog gene family, member T2" GO:0019866//organelle inner membrane;GO:0031306//intrinsic component of mitochondrial outer membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0046872//metal ion binding "GO:0042592//homeostatic process;GO:0012501//programmed cell death;GO:0034643//establishment of mitochondrion localization, microtubule-mediated;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction" gi|22122457|ref|NP_666111.1|/0/mitochondrial Rho GTPase 2 [Mus musculus] 67911 4170 0.333333333 0.19 -0.810966176 Down 0.217298507 Zfp169 zinc finger protein 169 K09228|1|0.0|1564|mmu:67911|KRAB domain-containing zinc finger protein - GO:0043169//cation binding;GO:0043169//cation binding;GO:0043169//cation binding - gi|257153346|ref|NP_080726.3|/0/zinc finger protein 169 isoform a [Mus musculus] 668225 4208 0.966666667 1.183333333 0.291766124 Up 0.217289105 Fignl2 fidgetin-like 2 K13254|1|2e-25|121|pps:100983006|spastin [EC:3.6.4.3] - - - "gi|148672121|gb|EDL04068.1|/3.07757e-146/mCG52237, partial [Mus musculus]" 12512 918 93.01 97.81666667 0.072694466 Up 0.21723269 Cd63 CD63 antigen K06497|1|8e-129|462|mmu:12512|CD63 antigen GO:0032991//macromolecular complex;GO:0030133//transport vesicle;GO:0005764//lysosome;GO:0016021//integral component of membrane;GO:0005770//late endosome;GO:0030667//secretory granule membrane;GO:0032991//macromolecular complex;GO:0030133//transport vesicle;GO:0005764//lysosome;GO:0016021//integral component of membrane;GO:0005770//late endosome;GO:0030667//secretory granule membrane;GO:0032991//macromolecular complex;GO:0030133//transport vesicle;GO:0005764//lysosome;GO:0016021//integral component of membrane;GO:0005770//late endosome;GO:0030667//secretory granule membrane GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0007599//hemostasis;GO:0010631//epithelial cell migration;GO:0007155//cell adhesion;GO:0010959;GO:0006887//exocytosis;GO:0008104//protein localization;GO:0006897//endocytosis;GO:0030154//cell differentiation;GO:0001775//cell activation;GO:0007599//hemostasis;GO:0010631//epithelial cell migration;GO:0007155//cell adhesion;GO:0010959;GO:0006887//exocytosis;GO:0008104//protein localization;GO:0006897//endocytosis;GO:0030154//cell differentiation;GO:0001775//cell activation;GO:0007599//hemostasis;GO:0010631//epithelial cell migration;GO:0007155//cell adhesion;GO:0010959;GO:0006887//exocytosis;GO:0008104//protein localization;GO:0006897//endocytosis;GO:0030154//cell differentiation;GO:0001775//cell activation gi|26389974|dbj|BAC25821.1|/1.72789e-130/unnamed protein product [Mus musculus] 209224 3952.53 2.196666667 1.906666667 -0.204263318 Down 0.217195081 Enox2 ecto-NOX disulfide-thiol exchanger 2 - GO:0009986//cell surface;GO:0016020//membrane GO:0015036//disulfide oxidoreductase activity;GO:0097159//organic cyclic compound binding GO:0051234//establishment of localization;GO:0044699;GO:0040007//growth;GO:0044710;GO:0006091//generation of precursor metabolites and energy "gi|148697143|gb|EDL29090.1|/0/cytosolic ovarian carcinoma antigen 1, isoform CRA_c, partial [Mus musculus]" 107581 5222 2.3 2.006666667 -0.196832875 Down 0.217195081 Col16a1 "collagen, type XVI, alpha 1" "K16630|1|4e-43|180|oaa:100082727|collagen, type XXII, alpha" - - GO:0043200//response to amino acid gi|568928185|ref|XP_006502711.1|/0/PREDICTED: collagen alpha-1(XVI) chain isoform X7 [Mus musculus] 234959 3914 3.99 4.386666667 0.136736337 Up 0.217148069 Med17 mediator complex subunit 17 K15133|1|0.0|1210|mmu:234959|mediator of RNA polymerase II transcription subunit 17 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter gi|21450345|ref|NP_659182.1|/0/mediator of RNA polymerase II transcription subunit 17 [Mus musculus] 242050 10084 0.263333333 0.413333333 0.650415562 Up 0.217119862 Igsf10 "immunoglobulin superfamily, member 10" K17341|1|1e-94|352|lcm:102351448|hemicentin GO:0016021//integral component of membrane GO:0032550;GO:0004714//transmembrane receptor protein tyrosine kinase activity GO:0048869//cellular developmental process;GO:0009888//tissue development;GO:0006464//cellular protein modification process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044707 gi|242247270|ref|NP_001156356.1|/0/immunoglobulin superfamily member 10 precursor [Mus musculus] 252973 4950 0.413333333 0.263333333 -0.650415562 Down 0.217119862 Grhl2 grainyhead-like 2 (Drosophila) K09275|1|0.0|1251|mmu:252973|transcription factor CP2 and related proteins - - - - 11695 5203 0.533333333 0.713333333 0.419538892 Up 0.217101057 Alx4 aristaless-like homeobox 4 K09451|1|0.0|727|mmu:11695|homeobox protein aristaless-like 4 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0003677//DNA binding GO:0001501//skeletal system development;GO:0008544//epidermis development;GO:0006366//transcription from RNA polymerase II promoter;GO:0048562//embryonic organ morphogenesis;GO:0006915//apoptotic process;GO:0030326//embryonic limb morphogenesis;GO:0003002//regionalization gi|6671541|ref|NP_031468.1|/0/homeobox protein aristaless-like 4 [Mus musculus] 16351 2118 2.4 2.103333333 -0.190356901 Down 0.217101057 Ipp IAP promoted placental gene K13956|1|0.0|1194|mmu:16351|actin-binding protein IPP - - - gi|111607439|ref|NP_032415.2|/0/actin-binding protein IPP [Mus musculus] 239122 3000 2.426666667 2.13 -0.188122519 Down 0.217101057 Setdb2 "SET domain, bifurcated 2" K18494|1|0.0|1078|mmu:107303348|histone-lysine N-methyltransferase SETDB2 [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0046914//transition metal ion binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0046914//transition metal ion binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0046914//transition metal ion binding;GO:0018024//histone-lysine N-methyltransferase activity GO:0034968//histone lysine methylation;GO:0000087//mitotic M phase;GO:0032502//developmental process;GO:0034968//histone lysine methylation;GO:0000087//mitotic M phase;GO:0032502//developmental process;GO:0034968//histone lysine methylation;GO:0000087//mitotic M phase;GO:0032502//developmental process gi|164430325|gb|ABY55488.1|/0/SET domain bifurcated protein 2 variant F [Mus musculus] 243743 12602 1.49 1.253333333 -0.24954217 Down 0.217082252 Plxna4 plexin A4 K06820|1|0.0|3821|mmu:243743|plexin A GO:0044464;GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity;GO:0005488//binding GO:0021564//vagus nerve development;GO:0007166//cell surface receptor signaling pathway;GO:0021563//glossopharyngeal nerve development;GO:0021561//facial nerve development;GO:0007422//peripheral nervous system development;GO:0021785//branchiomotor neuron axon guidance;GO:0021559//trigeminal nerve development;GO:0050919//negative chemotaxis;GO:0021537//telencephalon development;GO:0030516//regulation of axon extension gi|171543899|ref|NP_786926.2|/0/plexin-A4 precursor [Mus musculus] 11973 1219 88.07333333 92.67666667 0.073500886 Up 0.216931814 Atp6v1e1 "ATPase, H+ transporting, lysosomal V1 subunit E1" K02150|1|2e-84|315|cjc:100402779|V-type H+-transporting ATPase subunit E GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0042995//cell projection;GO:0044444//cytoplasmic part GO:0019829//cation-transporting ATPase activity "GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient" "gi|148667229|gb|EDK99645.1|/1.6096e-84/VATPase, H+ transporting, lysosomal V1 subunit E1, isoform CRA_a, partial [Mus musculus]" 15925 5087 14.71333333 13.82333333 -0.090018582 Down 0.216903607 Ide insulin degrading enzyme K01408|1|0.0|2038|mmu:15925|insulysin [EC:3.4.24.56] GO:0016020//membrane;GO:0000502//proteasome complex;GO:0044439;GO:0044421 GO:0032182//ubiquitin-like protein binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0017046//peptide hormone binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0042165//neurotransmitter binding;GO:0042802//identical protein binding GO:0043171//peptide catabolic process;GO:0010259//multicellular organism aging;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0031334//positive regulation of protein complex assembly;GO:0019725//cellular homeostasis;GO:0030163//protein catabolic process;GO:0009154//purine ribonucleotide catabolic process;GO:0006508//proteolysis;GO:0051260//protein homooligomerization gi|459352741|ref|NP_112419.3|/0/insulin-degrading enzyme [Mus musculus] 53424 2391 25.04 26.37666667 0.075027694 Up 0.216865997 Tsnax translin-associated factor X - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0043566//structure-specific DNA binding;GO:0031685//adenosine receptor binding GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|8394490|ref|NP_058605.1|/3.0214e-161/translin-associated protein X [Mus musculus] 109232 1922 22.92333333 24.26333333 0.081960919 Up 0.216865997 Sccpdh saccharopine dehydrogenase (putative) - GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle GO:0036094//small molecule binding;GO:0003824//catalytic activity GO:0044710 gi|30520019|ref|NP_848768.1|/0/saccharopine dehydrogenase-like oxidoreductase [Mus musculus] 99681 5823 0.216666667 0.1 -1.115477217 Down 0.216856595 Tchh trichohyalin K18626|1|6e-68|263|mmu:99681|trichohyalin - - - gi|251823773|ref|NP_001156570.1|/5.27567e-67/trichohyalin [Mus musculus] 102857 3977 93.99666667 98.48666667 0.067318826 Up 0.216818985 Slc6a8 "solute carrier family 6 (neurotransmitter transporter, creatine), member 8" "K05039|1|0.0|1150|mmu:102857|solute carrier family 6 (neurotransmitter transporter, GABA) member 6/8/11/12/13" GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005308//creatine transmembrane transporter activity;GO:0015651//quaternary ammonium group transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005308//creatine transmembrane transporter activity;GO:0015651//quaternary ammonium group transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005308//creatine transmembrane transporter activity;GO:0015651//quaternary ammonium group transmembrane transporter activity GO:0006575//cellular modified amino acid metabolic process;GO:0003012//muscle system process;GO:0072337;GO:0030001//metal ion transport;GO:0006575//cellular modified amino acid metabolic process;GO:0003012//muscle system process;GO:0072337;GO:0030001//metal ion transport;GO:0006575//cellular modified amino acid metabolic process;GO:0003012//muscle system process;GO:0072337;GO:0030001//metal ion transport "gi|148697940|gb|EDL29887.1|/0/solute carrier family 6 (neurotransmitter transporter, creatine), member 8, isoform CRA_a, partial [Mus musculus]" 70549 12150 9.63 8.966666667 -0.102964031 Down 0.216790778 Tln2 talin 2 K06271|1|0.0|4323|mmu:70549|talin - - - gi|568962056|ref|XP_006511501.1|/0/PREDICTED: talin-2 isoform X2 [Mus musculus] 72308 2755 10.31 9.65 -0.095443485 Down 0.216790778 Brf1 "BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit" K15196|1|0.0|1183|mmu:72308|transcription factor IIIB 90 kDa subunit - - - - 56330 642 98.96333333 94.50666667 -0.066477992 Down 0.216762571 Pdcd5 programmed cell death 5 K06875|1|9e-51|201|tup:102497556|programmed cell death protein 5 - - - - 12580 1541.7 6.906666667 7.47 0.113118646 Up 0.216734364 Cdkn2c "cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)" K06622|1|1e-82|310|mmu:12580|cyclin-dependent kinase inhibitor 2C GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019900//kinase binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019900//kinase binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity" GO:0012502//induction of programmed cell death;GO:0007417//central nervous system development;GO:0016049//cell growth;GO:0051726//regulation of cell cycle;GO:0044772//mitotic cell cycle phase transition;GO:0016310//phosphorylation;GO:0008283//cell proliferation;GO:0012502//induction of programmed cell death;GO:0007417//central nervous system development;GO:0016049//cell growth;GO:0051726//regulation of cell cycle;GO:0044772//mitotic cell cycle phase transition;GO:0016310//phosphorylation;GO:0008283//cell proliferation "gi|148698751|gb|EDL30698.1|/3.06927e-82/cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4), isoform CRA_b, partial [Mus musculus]" 66975 3460.94 7.933333333 7.37 -0.106262548 Down 0.216734364 Trappc13 trafficking protein particle complex 13 K20310|1|0.0|753|mmu:66975|trafficking protein particle complex subunit 13 - - - "gi|148686557|gb|EDL18504.1|/0/RIKEN cDNA 2410002O22, isoform CRA_c, partial [Mus musculus]" 68948 1014 7.893333333 7.33 -0.106821477 Down 0.216734364 Fam216a "family with sequence similarity 216, member A" - - - - "gi|148687738|gb|EDL19685.1|/1.40196e-149/RIKEN cDNA 1500011H22, isoform CRA_b, partial [Mus musculus]" 208043 8868 7.403333333 6.846666667 -0.112773211 Down 0.216734364 Setd1b SET domain containing 1B K11422|1|0.0|956|mmu:208043|histone-lysine N-methyltransferase SETD1 [EC:2.1.1.43] - - - gi|568937010|ref|XP_006530300.1|/0/PREDICTED: histone-lysine N-methyltransferase SETD1B isoform X1 [Mus musculus] 338355 4363 7.913333333 7.353333333 -0.105887144 Down 0.216734364 Fkbp15 FK506 binding protein 15 K17478|1|0.0|2060|mmu:338355|FK506-binding protein 15 GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0003824//catalytic activity GO:0016192//vesicle-mediated transport;GO:0044267//cellular protein metabolic process;GO:0010921//regulation of phosphatase activity "gi|38614309|gb|AAH60651.1|/0/Fkbp15 protein, partial [Mus musculus]" 12161 2996 25.06 23.72666667 -0.078876983 Down 0.216706157 Bmp6 bone morphogenetic protein 6 K16620|1|0.0|812|mmu:12161|bone morphogenetic protein 6 - - - - 494468 2835 3.033333333 2.7 -0.167944637 Down 0.216696754 Armcx5 "armadillo repeat containing, X-linked 5" K14284|1|5e-17|92.8|rno:680025|nuclear RNA export factor - - - gi|85662391|ref|NP_001009575.2|/0/armadillo repeat-containing X-linked protein 5 [Mus musculus] 69656 1554.91 2.57 2.9 0.174284541 Up 0.216696754 Pir pirin K06911|1|2e-169|597|mmu:69656|uncharacterized protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0000989//transcription factor activity, transcription factor binding;GO:0043169//cation binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0000989//transcription factor activity, transcription factor binding;GO:0043169//cation binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" "GO:0044710;GO:0002573//myeloid leukocyte differentiation;GO:0006351//transcription, DNA-templated;GO:0044710;GO:0002573//myeloid leukocyte differentiation;GO:0006351//transcription, DNA-templated" gi|51317401|ref|NP_081429.1|/2.01643e-168/pirin isoform 1 [Mus musculus] 118453 3456 2.98 2.653333333 -0.167506401 Down 0.216696754 Mmp28 matrix metallopeptidase 28 (epilysin) K08006|1|0.0|951|mmu:118453|matrix metalloproteinase-28 (epilysin) [EC:3.4.24.-] - "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process "gi|148683760|gb|EDL15707.1|/0/matrix metallopeptidase 28 (epilysin), isoform CRA_d, partial [Mus musculus]" 54169 7223 3.273333333 2.926666667 -0.161502085 Down 0.216668547 Kat6b K(lysine) acetyltransferase 6B K11306|1|0.0|2978|mmu:54169|histone acetyltransferase MYST4 [EC:2.3.1.48] GO:0000785//chromatin;GO:0070775;GO:0000785//chromatin;GO:0070775 GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0008080//N-acetyltransferase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0008080//N-acetyltransferase activity "GO:0006351//transcription, DNA-templated;GO:0034728//nucleosome organization;GO:0016573//histone acetylation;GO:0006351//transcription, DNA-templated;GO:0034728//nucleosome organization;GO:0016573//histone acetylation" gi|110556652|ref|NP_059507.2|/0/histone acetyltransferase KAT6B [Mus musculus] 13121 4353 3.723333333 3.356666667 -0.149565502 Down 0.216649742 Cyp51 "cytochrome P450, family 51" K05917|1|0.0|991|mmu:13121|sterol 14-demethylase [EC:1.14.13.70] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen" GO:0006695//cholesterol biosynthetic process gi|71061451|ref|NP_064394.2|/0/lanosterol 14-alpha demethylase [Mus musculus] 229589 3160 14.32666667 15.20333333 0.085684687 Up 0.21664034 Prune prune exopolyphosphatase K01514|1|0.0|875|mmu:229589|exopolyphosphatase [EC:3.6.1.11] - - - - 66839 2407 86.37 90.72 0.070890351 Up 0.21664034 0610009O20Rik RIKEN cDNA 0610009O20 gene K14026|1|9e-20|101|ame:724401|SEL1 protein GO:0043231//intracellular membrane-bounded organelle - GO:0006915//apoptotic process gi|50510385|dbj|BAD32178.1|/0/mKIAA0141 protein [Mus musculus] 73158 6617 24.01333333 22.69666667 -0.081355248 Down 0.216565121 Larp1 "La ribonucleoprotein domain family, member 1" K18757|1|0.0|1751|mmu:73158|la-related protein 1 - - - gi|226442901|ref|NP_082727.1|/0/la-related protein 1 [Mus musculus] 17857 3218 0.5 0.343333333 -0.542318163 Down 0.216555719 Mx1 MX dynamin-like GTPase 1 K14754|1|2e-108|396|mmu:17858|interferon-induced GTP-binding protein Mx1 GO:0005635//nuclear envelope;GO:0044444//cytoplasmic part GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0006913//nucleocytoplasmic transport;GO:0051707//response to other organism;GO:0019079//viral genome replication;GO:0034097//response to cytokine;GO:0002252;GO:0009154//purine ribonucleotide catabolic process;GO:0006952//defense response;GO:0007049//cell cycle gi|6996930|ref|NP_034976.1|/0/interferon-induced GTP-binding protein Mx1 [Mus musculus] 109113 3595 5.373333333 5.85 0.122619287 Up 0.216518109 Uhrf2 "ubiquitin-like, containing PHD and RING finger domains 2" K15713|1|0.0|1628|mmu:109113|E3 ubiquitin-protein ligase UHRF2 [EC:2.3.2.27] GO:0000790//nuclear chromatin GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity GO:0007050//cell cycle arrest;GO:0048869//cellular developmental process;GO:0019941//modification-dependent protein catabolic process;GO:0016567//protein ubiquitination gi|124430766|ref|NP_659122.2|/0/E3 ubiquitin-protein ligase UHRF2 [Mus musculus] 11773 2935.8 89.82666667 94.07333333 0.066642026 Up 0.216508707 Ap2m1 "adaptor-related protein complex 2, mu 1 subunit" K11826|1|0.0|862|mcc:703554|AP-2 complex subunit mu-1 GO:0030119//AP-type membrane coat adaptor complex;GO:0005764//lysosome;GO:0030665//clathrin-coated vesicle membrane;GO:0005905//clathrin-coated pit;GO:0030139//endocytic vesicle;GO:0030118//clathrin coat;GO:0030119//AP-type membrane coat adaptor complex;GO:0005764//lysosome;GO:0030665//clathrin-coated vesicle membrane;GO:0005905//clathrin-coated pit;GO:0030139//endocytic vesicle;GO:0030118//clathrin coat GO:0005488//binding;GO:0005488//binding GO:0007267//cell-cell signaling;GO:0015031//protein transport;GO:0044764;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0050688//regulation of defense response to virus;GO:0006935//chemotaxis;GO:0002478;GO:0007267//cell-cell signaling;GO:0015031//protein transport;GO:0044764;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0050688//regulation of defense response to virus;GO:0006935//chemotaxis;GO:0002478 gi|6753074|ref|NP_033809.1|/0/AP-2 complex subunit mu isoform 1 [Mus musculus] 56436 1429 90.68 94.92 0.065927709 Up 0.216499304 Adrm1 adhesion regulating molecule 1 K20174|1|2e-76|289|umr:103660548|oxysterol-binding protein-related protein 1/2 GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0043234//protein complex GO:0061135;GO:0032403//protein complex binding;GO:0019899//enzyme binding GO:0010952//positive regulation of peptidase activity;GO:0001541//ovarian follicle development;GO:0006366//transcription from RNA polymerase II promoter;GO:0008584//male gonad development;GO:0009967//positive regulation of signal transduction;GO:0033077//T cell differentiation in thymus;GO:0007281//germ cell development;GO:0043623//cellular protein complex assembly;GO:0007292//female gamete generation gi|568920357|ref|XP_006500743.1|/1.22801e-81/PREDICTED: proteasomal ubiquitin receptor ADRM1 isoform X1 [Mus musculus] 791299 3922 1.15 1.376666667 0.25954542 Up 0.216471097 Gm10069 predicted gene 10069 K03910|1|5e-07|58.5|bacu:103017080|alpha-2-macroglobulin GO:0030532//small nuclear ribonucleoprotein complex;GO:0016604//nuclear body;GO:0044421;GO:0031988//membrane-bounded vesicle GO:0008144//drug binding;GO:0016859//cis-trans isomerase activity;GO:0005515//protein binding;GO:0004866//endopeptidase inhibitor activity GO:0019079//viral genome replication;GO:0018208//peptidyl-proline modification;GO:0000377;GO:0065003;GO:0010466//negative regulation of peptidase activity "gi|148667474|gb|EDK99890.1|/2.94901e-25/pregnancy zone protein, isoform CRA_a [Mus musculus]" 20981 2497 1.143333333 1.373333333 0.264435761 Up 0.216471097 Syt3 synaptotagmin III K19903|1|0.0|832|ssc:100511086|synaptotagmin-3 GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane GO:0046872//metal ion binding;GO:0000149//SNARE binding;GO:0005543//phospholipid binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0046872//metal ion binding;GO:0000149//SNARE binding;GO:0005543//phospholipid binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity GO:0010038//response to metal ion;GO:0006906//vesicle fusion;GO:0006887//exocytosis;GO:0010038//response to metal ion;GO:0006906//vesicle fusion;GO:0006887//exocytosis gi|537146721|gb|ERE70163.1|/0/synaptotagmin-3-like protein [Cricetulus griseus] 67808 1756 84.17 88.39 0.070577042 Up 0.216452292 Tprgl transformation related protein 63 regulated like - GO:0030136//clathrin-coated vesicle GO:0005515//protein binding - gi|21312776|ref|NP_080664.1|/5.63365e-151/tumor protein p63-regulated gene 1-like protein [Mus musculus] 11641 6729.02 24.81 23.50333333 -0.078056355 Down 0.21640528 Akap2 A kinase (PRKA) anchor protein 2 K16519|1|0.0|1610|mmu:677884|A-kinase anchor protein 2 GO:0032991//macromolecular complex;GO:0032991//macromolecular complex;GO:0032991//macromolecular complex GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0033036;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0051259//protein oligomerization;GO:0033036;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0051259//protein oligomerization;GO:0033036;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0051259//protein oligomerization gi|752507732|ref|NP_001291473.1|/0/paralemmin A kinase anchor protein [Mus musculus] 68832 2690.09 9.126666667 9.776666667 0.099254624 Up 0.21624544 Ldah lipid droplet associated hydrolase K00106|1|2e-42|177|bfo:BRAFLDRAFT_117011|xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2];K10591|2|1e-06|58.5|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] - - - gi|269995975|ref|NP_765989.3|/0/lipid droplet-associated hydrolase isoform 1 [Mus musculus] 67440 2651 10.01666667 9.366666667 -0.09679486 Down 0.21624544 Mtpap mitochondrial poly(A) polymerase "K18060|1|0.0|1111|mmu:67440|poly(A) RNA polymerase, mitochondrial [EC:2.7.7.19]" GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0070566//adenylyltransferase activity;GO:0032551 GO:0031124//mRNA 3'-end processing;GO:0000956//nuclear-transcribed mRNA catabolic process "gi|148691104|gb|EDL23051.1|/0/PAP associated domain containing 1, isoform CRA_b, partial [Mus musculus]" 230903 1620.64 10.09 9.443333333 -0.095558073 Down 0.21624544 Fbxo44 F-box protein 44 K10103|1|4e-142|507|mmu:230903|F-box protein 44 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex GO:0005488//binding GO:0009057//macromolecule catabolic process;GO:0009057//macromolecule catabolic process;GO:0009057//macromolecule catabolic process;GO:0009057//macromolecule catabolic process gi|564354083|ref|XP_006239455.1|/8.24528e-130/PREDICTED: F-box only protein 44 isoform X3 [Rattus norvegicus] 229323 2225 0.026666667 0.123333333 2.209453366 Up 0.216236037 Gpr171 G protein-coupled receptor 171 K08441|1|1e-172|609|mmu:229323|G protein-coupled receptor 171 GO:0031224//intrinsic component of membrane GO:0001608 GO:0035588 gi|27734176|ref|NP_775574.1|/1.01702e-171/probable G-protein coupled receptor 171 [Mus musculus] 22628 3592 87.43 91.49333333 0.065538226 Up 0.216236037 Ywhag "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide" K16198|1|2e-128|462|amj:102575827|14-3-3 protein gamma/eta GO:0044444//cytoplasmic part GO:0005102//receptor binding;GO:0019901//protein kinase binding;GO:0030291//protein serine/threonine kinase inhibitor activity GO:0044772//mitotic cell cycle phase transition;GO:0006886//intracellular protein transport;GO:0001933//negative regulation of protein phosphorylation;GO:0044710;GO:0007165//signal transduction;GO:0050804//modulation of synaptic transmission;GO:0030182//neuron differentiation gi|564378965|ref|XP_006249246.1|/1.23507e-156/PREDICTED: 14-3-3 protein gamma isoform X1 [Rattus norvegicus] 15259 7495.3 22.18666667 23.48666667 0.082149041 Up 0.216226635 Hipk3 homeodomain interacting protein kinase 3 K08826|1|0.0|2285|mmu:15259|homeodomain interacting protein kinase [EC:2.7.11.1] GO:0016604//nuclear body;GO:0016604//nuclear body GO:0032550;GO:0003712//transcription cofactor activity;GO:0004672//protein kinase activity;GO:0003676//nucleic acid binding;GO:0032550;GO:0003712//transcription cofactor activity;GO:0004672//protein kinase activity;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0051099//positive regulation of binding;GO:0043407//negative regulation of MAP kinase activity;GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0051099//positive regulation of binding;GO:0043407//negative regulation of MAP kinase activity;GO:0006915//apoptotic process" gi|224922826|ref|NP_001139296.1|/0/homeodomain-interacting protein kinase 3 isoform 2 [Mus musculus] 70616 2287 25.23666667 23.93666667 -0.076299106 Down 0.216226635 Sugp1 SURP and G patch domain containing 1 K13096|1|0.0|1128|mmu:70616|splicing factor 4 GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding GO:0000377 "gi|148696829|gb|EDL28776.1|/0/splicing factor 4, isoform CRA_c, partial [Mus musculus]" 380839 1599 0.85 0.656666667 -0.372301617 Down 0.216226635 Serpinb1c "serine (or cysteine) peptidase inhibitor, clade B, member 1c" K13963|1|0.0|745|mmu:380839|serpin B - - - gi|568981897|ref|XP_006516771.1|/0/PREDICTED: leukocyte elastase inhibitor C isoform X1 [Mus musculus] 21945 2709.21 12.85 13.71666667 0.094161571 Up 0.216217233 Dedd death effector domain-containing - GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0009895;GO:0001893//maternal placenta development;GO:0012502//induction of programmed cell death;GO:0048232//male gamete generation;GO:0097191//extrinsic apoptotic signaling pathway;GO:0006351//transcription, DNA-templated;GO:0009895;GO:0001893//maternal placenta development;GO:0012502//induction of programmed cell death;GO:0048232//male gamete generation;GO:0097191//extrinsic apoptotic signaling pathway" gi|548456234|ref|XP_005677234.1|/0/PREDICTED: death effector domain-containing protein [Capra hircus] 67742 1845 0.186666667 0.323333333 0.79255792 Up 0.216179623 Samsn1 "SAM domain, SH3 domain and nuclear localization signals, 1" - - - - - 319973 957 0.106666667 0.226666667 1.087462841 Up 0.216160818 A630077J23Rik RIKEN cDNA A630077J23 gene - - - - - 241520 3394 0.13 0.03 -2.115477217 Down 0.216132611 Fam171b "family with sequence similarity 171, member B" K06476|1|1e-12|78.6|fpg:101913845|integrin alpha 2B - - - gi|28202059|ref|NP_780723.1|/0/protein FAM171B precursor [Mus musculus] 226841 3912 0.03 0.133333333 2.152003093 Up 0.216132611 Vash2 vasohibin 2 - - - - - 18550 4242.01 78.36666667 82.34666667 0.071470119 Up 0.216132611 Furin furin (paired basic amino acid cleaving enzyme) K01349|1|0.0|1458|mmu:18550|furin [EC:3.4.21.75] - - - gi|6754996|ref|NP_035176.1|/0/furin preproprotein [Mus musculus] 56462 1918 80.84666667 84.81333333 0.069102794 Up 0.216123209 Mtch1 mitochondrial carrier 1 K17885|1|0.0|656|mmu:56462|mitochondrial carrier GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0005488//binding GO:0006915//apoptotic process;GO:0051234//establishment of localization;GO:0007165//signal transduction gi|9845273|ref|NP_063933.1|/0/mitochondrial carrier homolog 1 [Mus musculus] 64138 1454 23.04666667 24.33666667 0.078573476 Up 0.216095002 Ctsz cathepsin Z K08568|1|5e-174|613|mmu:64138|cathepsin X [EC:3.4.18.1] - - - - 20779 3869 1.866666667 1.606666667 -0.216393681 Down 0.21604799 Src Rous sarcoma oncogene K05704|1|0.0|1107|mmu:20779|tyrosine-protein kinase Src [EC:2.7.10.2] GO:0000323//lytic vacuole;GO:0043232;GO:0019866//organelle inner membrane;GO:0044459;GO:0044327//dendritic spine head;GO:0005768//endosome;GO:0019866//organelle inner membrane;GO:0005768//endosome;GO:0044327//dendritic spine head;GO:0043232;GO:0000323//lytic vacuole;GO:0044459 "GO:0004713//protein tyrosine kinase activity;GO:0035258//steroid hormone receptor binding;GO:0046906//tetrapyrrole binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0019901//protein kinase binding;GO:0019901//protein kinase binding;GO:0030674//protein binding, bridging;GO:0035258//steroid hormone receptor binding;GO:0046906//tetrapyrrole binding;GO:0019904//protein domain specific binding;GO:0004713//protein tyrosine kinase activity;GO:0032550" "GO:0006006//glucose metabolic process;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0001894//tissue homeostasis;GO:0043405//regulation of MAP kinase activity;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0048754//branching morphogenesis of an epithelial tube;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007420//brain development;GO:0007292//female gamete generation;GO:0032147//activation of protein kinase activity;GO:0032460//negative regulation of protein oligomerization;GO:0050663//cytokine secretion;GO:0097193//intrinsic apoptotic signaling pathway;GO:0006351//transcription, DNA-templated;GO:0043410//positive regulation of MAPK cascade;GO:0031960//response to corticosteroid;GO:0001666//response to hypoxia;GO:0045216//cell-cell junction organization;GO:0097191//extrinsic apoptotic signaling pathway;GO:0032570//response to progesterone;GO:0000302//response to reactive oxygen species;GO:0051098//regulation of binding;GO:0031334//positive regulation of protein complex assembly;GO:0009991//response to extracellular stimulus;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0016192//vesicle-mediated transport;GO:0038127//ERBB signaling pathway;GO:0014909//smooth muscle cell migration;GO:0001953//negative regulation of cell-matrix adhesion;GO:0043066//negative regulation of apoptotic process;GO:0070542//response to fatty acid;GO:0034097//response to cytokine;GO:0008286//insulin receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0070542//response to fatty acid;GO:0034097//response to cytokine;GO:0001894//tissue homeostasis;GO:0045216//cell-cell junction organization;GO:0038127//ERBB signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0006935//chemotaxis;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0032844//regulation of homeostatic process;GO:0097193//intrinsic apoptotic signaling pathway;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0001953//negative regulation of cell-matrix adhesion;GO:0003018;GO:0032496//response to lipopolysaccharide;GO:0031960//response to corticosteroid;GO:0031334//positive regulation of protein complex assembly;GO:0007292//female gamete generation;GO:0032460//negative regulation of protein oligomerization;GO:0051098//regulation of binding;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006006//glucose metabolic process;GO:0032570//response to progesterone;GO:0001666//response to hypoxia;GO:0007264//small GTPase mediated signal transduction;GO:0007420//brain development;GO:0006351//transcription, DNA-templated;GO:0050663//cytokine secretion;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0009991//response to extracellular stimulus;GO:0030177//positive regulation of Wnt signaling pathway;GO:0016192//vesicle-mediated transport;GO:0043410//positive regulation of MAPK cascade;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032147//activation of protein kinase activity;GO:0031294//lymphocyte costimulation;GO:0097191//extrinsic apoptotic signaling pathway;GO:0000302//response to reactive oxygen species;GO:0008286//insulin receptor signaling pathway;GO:0043405//regulation of MAP kinase activity;GO:0014909//smooth muscle cell migration;GO:0007599//hemostasis" gi|70794809|ref|NP_001020566.1|/0/neuronal proto-oncogene tyrosine-protein kinase Src isoform 2 [Mus musculus] 30955 6634 0.513333333 0.356666667 -0.525319554 Down 0.215916356 Pik3cg "phosphoinositide-3-kinase, catalytic, gamma polypeptide" "K00922|1|0.0|2222|mmu:30955|phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]" - - - "gi|148704947|gb|EDL36894.1|/0/phosphoinositide-3-kinase, catalytic, gamma polypeptide, isoform CRA_b, partial [Mus musculus]" 328734 1485 0.35 0.506666667 0.533681996 Up 0.215916356 Pisd-ps2 "phosphatidylserine decarboxylase, pseudogene 2" K01613|1|2e-172|457|ngi:103740422|phosphatidylserine decarboxylase [EC:4.1.1.65] - - - - 13858 5065.46 7.266666667 6.713333333 -0.114264452 Down 0.215897552 Eps15 epidermal growth factor receptor pathway substrate 15 K12472|1|0.0|1408|mmu:13858|epidermal growth factor receptor substrate 15 GO:0030128//clathrin coat of endocytic vesicle;GO:0030128//clathrin coat of endocytic vesicle GO:0043169//cation binding;GO:0019904//protein domain specific binding;GO:0005515//protein binding GO:0006901//vesicle coating;GO:0045184//establishment of protein localization;GO:0006901//vesicle coating gi|6679671|ref|NP_031969.1|/0/epidermal growth factor receptor substrate 15 isoform A [Mus musculus] 17692 3338 14.61666667 13.75333333 -0.087833021 Down 0.21581293 Msl3 male-specific lethal 3 homolog (Drosophila) K18403|1|0.0|755|cge:100760785|male-specific lethal 3 - - - - 69170 5157 1.476666667 1.73 0.22842784 Up 0.215794125 1810026B05Rik RIKEN cDNA 1810026B05 gene - - - - - 14362 4395 1.646666667 1.4 -0.234121714 Down 0.215794125 Fzd1 frizzled class receptor 1 K02432|1|0.0|1185|mmu:14362|frizzled 1/7 - - - - 216157 2223 73.54 77.35666667 0.072996453 Up 0.215756516 Tmem259 transmembrane protein 259 - GO:0016020//membrane - - gi|53759066|ref|NP_001003949.2|/0/membralin [Mus musculus] 51938 3616 0.106666667 0.223333333 1.06608919 Up 0.215671894 Ccdc39 coiled-coil domain containing 39 "K13675|1|0.0|774|cin:100184083|UDP-glucose:O-linked fucose beta-1,3-glucosyltransferase [EC:2.4.1.-];K20282|2|2e-94|350|tca:661131|GRIP and coiled-coil domain-containing protein 2;K10402|5|2e-32|144|sko:100368346|kinesin family member 20" GO:0043232;GO:0005930//axoneme - GO:0030323//respiratory tube development;GO:0001889//liver development;GO:0043623//cellular protein complex assembly;GO:0001539//cilium or flagellum-dependent cell motility;GO:0007368//determination of left/right symmetry;GO:0003351//epithelial cilium movement gi|21312922|ref|NP_080498.1|/0/coiled-coil domain-containing protein 39 [Mus musculus] 100042514 852 0.223333333 0.106666667 -1.06608919 Down 0.215671894 Sprr2a3 small proline-rich protein 2A3 - GO:0043231//intracellular membrane-bounded organelle - GO:0043627//response to estrogen;GO:0022604//regulation of cell morphogenesis;GO:0008544//epidermis development "gi|118196867|gb|AAI16763.1|/7.95523e-17/Sprr2e protein, partial [Mus musculus]" 66190 4058 1.063333333 1.286666667 0.275044424 Up 0.21565309 Acer3 alkaline ceramidase 3 K04711|1|7e-159|564|mmu:66190|dihydroceramidase [EC:3.5.1.-] - - - gi|84794581|ref|NP_079684.2|/5.73873e-158/alkaline ceramidase 3 [Mus musculus] 208968 3960 1.043333333 1.263333333 0.276035191 Up 0.21565309 Zfp280c zinc finger protein 280C K09228|1|9e-17|92.4|bfo:BRAFLDRAFT_58764|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|37360462|dbj|BAC98209.1|/0/mKIAA1584 protein [Mus musculus] 26444 961.58 77.96 81.67333333 0.067131019 Up 0.215549663 Psma7 "proteasome (prosome, macropain) subunit, alpha type 7" K02731|1|9e-122|438|cge:100769350|20S proteasome subunit alpha 4 [EC:3.4.25.1] GO:0005839//proteasome core complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005839//proteasome core complex;GO:0043231//intracellular membrane-bounded organelle GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0004175//endopeptidase activity;GO:0005515//protein binding GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process gi|7106389|ref|NP_036099.1|/7.25469e-121/proteasome subunit alpha type-7 isoform 1 [Mus musculus] 68737 3867 2.286666667 2.596666667 0.183414752 Up 0.215540261 Angel1 angel homolog 1 (Drosophila) K18729|1|0.0|1264|mmu:68737|protein angel - - - "gi|148670957|gb|EDL02904.1|/0/angel homolog 1 (Drosophila), partial [Mus musculus]" 52428 3439 2.663333333 2.356666667 -0.176485288 Down 0.215540261 Rhpn2 "rhophilin, Rho GTPase binding protein 2" "K01770|1|2e-29|134|aqu:105312342|2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12];K18040|2|1e-27|128|dre:100007322|tyrosine-protein phosphatase non-receptor type 23 [EC:3.1.3.48]" GO:0044444//cytoplasmic part - GO:0007154//cell communication "gi|148671074|gb|EDL03021.1|/0/rhophilin, Rho GTPase binding protein 2, isoform CRA_b, partial [Mus musculus]" 17688 4288 2.613333333 2.3 -0.184257292 Down 0.215540261 Msh6 mutS homolog 6 K08737|1|0.0|2397|mmu:17688|DNA mismatch repair protein MSH6 - - - "gi|148706690|gb|EDL38637.1|/0/mCG15886, partial [Mus musculus]" 70209 2184 76.24 79.91 0.067827935 Up 0.215483847 Tmem143 transmembrane protein 143 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - "gi|148690962|gb|EDL22909.1|/0/transmembrane protein 143, isoform CRA_c, partial [Mus musculus]" 210789 6641 8.733333333 9.37 0.101516642 Up 0.215465042 Tbc1d4 "TBC1 domain family, member 4" K17902|1|0.0|2315|mmu:210789|TBC1 domain family member 4 - - - - 233552 3609 9.32 9.956666667 0.095332877 Up 0.215465042 Gdpd5 glycerophosphodiester phosphodiesterase domain containing 5 K01124|1|3e-124|449|apla:101792816|glycerophosphoinositol inositolphosphodiesterase [EC:3.1.4.43] GO:0031224//intrinsic component of membrane;GO:0044424 GO:0008081//phosphoric diester hydrolase activity "GO:0021515//cell differentiation in spinal cord;GO:0030030//cell projection organization;GO:0007219//Notch signaling pathway;GO:0021953//central nervous system neuron differentiation;GO:0019400;GO:0040034//regulation of development, heterochronic" gi|52345431|ref|NP_958740.2|/0/glycerophosphodiester phosphodiesterase domain-containing protein 5 [Mus musculus] 320351 1058.91 9.666666667 9.026666667 -0.098825161 Down 0.215465042 Tmem251 transmembrane protein 251 K11979|1|1e-21|106|fab:101819424|E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27] GO:0031224//intrinsic component of membrane - - gi|28893105|ref|NP_796114.1|/6.02272e-84/transmembrane protein 251 [Mus musculus] 66423 802 9.383333333 10.02666667 0.095669645 Up 0.215465042 Coprs "coordinator of PRMT5, differentiation stimulator" - GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding "GO:0034969//histone arginine methylation;GO:0048513//animal organ development;GO:0006351//transcription, DNA-templated" gi|13384986|ref|NP_079832.1|/5.70678e-99/coordinator of PRMT5 and differentiation stimulator [Mus musculus] 226695 1613 14.33 13.47666667 -0.088574907 Down 0.215436835 Ifi205 interferon activated gene 205 K12971|1|3e-59|232|mmu:26388|interferon-activable protein 202;K12966|5|1e-37|160|mcc:719260|absent in melanoma 2 GO:0016604//nuclear body "GO:0005515//protein binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0043566//structure-specific DNA binding" GO:0001649//osteoblast differentiation;GO:0048519;GO:0006366//transcription from RNA polymerase II promoter;GO:0048518;GO:0043583//ear development;GO:0072331//signal transduction by p53 class mediator;GO:2000116//regulation of cysteine-type endopeptidase activity;GO:0097193//intrinsic apoptotic signaling pathway;GO:0050776//regulation of immune response;GO:0044092//negative regulation of molecular function;GO:0051704;GO:0031347//regulation of defense response;GO:0016049//cell growth;GO:0033554//cellular response to stress;GO:0035456//response to interferon-beta gi|31982556|ref|NP_766236.2|/0/interferon-activable protein 205-A [Mus musculus] 27801 4887 13.77333333 14.62333333 0.086394452 Up 0.215436835 Zdhhc8 "zinc finger, DHHC domain containing 8" K20030|1|0.0|1347|mmu:27801|palmitoyltransferase ZDHHC5/8 [EC:2.3.1.225] GO:0012506//vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0046914//transition metal ion binding" GO:0050896//response to stimulus;GO:0006497//protein lipidation gi|157057160|ref|NP_742163.4|/0/probable palmitoyltransferase ZDHHC8 [Mus musculus] 67767 1171.89 12.76666667 13.61666667 0.092991686 Up 0.215436835 Jagn1 jagunal homolog 1 K05168|1|8e-27|81.3|hgl:101700580|interleukin 17 receptor E;K19531|5|3e-15|85.5|sko:102803675|codanin-1 - - - - 192156 1784.92 3.74 4.126666667 0.141938639 Up 0.215427432 Mvd mevalonate (diphospho) decarboxylase K01597|1|2e-178|628|mmu:192156|diphosphomevalonate decarboxylase [EC:4.1.1.33] GO:0044439;GO:0044439 GO:0032550;GO:0031072//heat shock protein binding;GO:0042802//identical protein binding;GO:0016831//carboxy-lyase activity;GO:0032550;GO:0031072//heat shock protein binding;GO:0042802//identical protein binding;GO:0016831//carboxy-lyase activity GO:0006084//acetyl-CoA metabolic process;GO:0042221//response to chemical;GO:0006720//isoprenoid metabolic process;GO:0006694//steroid biosynthetic process;GO:0008283//cell proliferation;GO:0008203//cholesterol metabolic process;GO:0006084//acetyl-CoA metabolic process;GO:0042221//response to chemical;GO:0006720//isoprenoid metabolic process;GO:0006694//steroid biosynthetic process;GO:0008283//cell proliferation;GO:0008203//cholesterol metabolic process gi|256985114|ref|NP_619597.2|/1.3036e-177/diphosphomevalonate decarboxylase [Mus musculus] 329065 3072 3.883333333 4.276666667 0.139191216 Up 0.215427432 Scd4 stearoyl-coenzyme A desaturase 4 K00507|1|0.0|741|mmu:329065|stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1] GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0046914//transition metal ion binding;GO:0016215//acyl-CoA desaturase activity GO:0006631//fatty acid metabolic process;GO:0042742//defense response to bacterium;GO:0034434//sterol esterification;GO:0044126;GO:0045444//fat cell differentiation gi|38261958|ref|NP_899039.2|/0/acyl-CoA desaturase 4 [Mus musculus] 69499 3807.92 3.86 4.253333333 0.139993076 Up 0.215427432 Tsr2 TSR2 20S rRNA accumulation K14800|1|2e-85|320|mmu:69499|pre-rRNA-processing protein TSR2 GO:0043231//intracellular membrane-bounded organelle;GO:0031252//cell leading edge;GO:0043232 GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0051020//GTPase binding;GO:0043169//cation binding;GO:0008289//lipid binding GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis;GO:0030031//cell projection assembly;GO:0042254//ribosome biogenesis;GO:0042254//ribosome biogenesis;GO:0042254//ribosome biogenesis gi|257153359|ref|NP_001158050.1|/9.679e-83/pre-rRNA-processing protein TSR2 homolog isoform 1 [Mus musculus] 235047 1623.33 4.22 3.826666667 -0.141154763 Down 0.215427432 Zfp809 zinc finger protein 809 K09228|1|0.0|855|mmu:235047|KRAB domain-containing zinc finger protein - - - gi|257467484|ref|NP_001158096.1|/0/zinc finger protein 809 isoform 2 [Mus musculus] 242607 3005 0.113333333 0.236666667 1.062284278 Up 0.215399225 Slc1a7 "solute carrier family 1 (glutamate transporter), member 7" "K05618|1|0.0|967|mmu:242607|solute carrier family 1 (glutamate transporter), member 7" GO:0031224//intrinsic component of membrane GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0046942//carboxylic acid transport gi|295148146|ref|NP_666367.2|/0/excitatory amino acid transporter 5 [Mus musculus] 19331 1371 0.113333333 0.236666667 1.062284278 Up 0.215399225 Rab19 "RAB19, member RAS oncogene family" K17047|1|1e-119|432|mmu:19331|Ras-related protein Rab-19 GO:0016020//membrane GO:0032550 GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization gi|33859608|ref|NP_035356.1|/1.18702e-118/ras-related protein Rab-19 [Mus musculus] 106628 2433.06 73.37 69.74666667 -0.073066016 Down 0.215352213 Trip10 thyroid hormone receptor interactor 10 K07196|1|0.0|883|rno:116717|thyroid hormone receptor interactor 10 GO:0000323//lytic vacuole;GO:0016020//membrane;GO:0015630//microtubule cytoskeleton;GO:0000323//lytic vacuole;GO:0016020//membrane;GO:0015630//microtubule cytoskeleton;GO:0000323//lytic vacuole;GO:0016020//membrane;GO:0015630//microtubule cytoskeleton;GO:0000323//lytic vacuole;GO:0016020//membrane;GO:0015630//microtubule cytoskeleton GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0006972//hyperosmotic response;GO:0016192//vesicle-mediated transport;GO:0006972//hyperosmotic response;GO:0016192//vesicle-mediated transport;GO:0006972//hyperosmotic response;GO:0016192//vesicle-mediated transport;GO:0006972//hyperosmotic response;GO:0016192//vesicle-mediated transport "gi|148706307|gb|EDL38254.1|/0/thyroid hormone receptor interactor 10, isoform CRA_a, partial [Mus musculus]" 192236 2800 0.79 0.993333333 0.330425272 Up 0.215258189 Hps1 Hermansky-Pudlak syndrome 1 K20193|1|0.0|1310|mmu:192236|Hermansky-Pudlak syndrome 1 protein - - - - 68281 2419 0.76 0.956666667 0.332016913 Up 0.215258189 4930430F08Rik RIKEN cDNA 4930430F08 gene K16533|1|3e-18|96.7|mmu:216274|centrosomal protein CEP290 - - - gi|171906608|ref|NP_780337.2|/0/uncharacterized protein C12orf29 homolog [Mus musculus] 69277 648 0.24 0.12 -1 Down 0.215239385 3300002I08Rik RIKEN cDNA 3300002I08 gene K09228|1|6e-28|125|mmu:245174|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|225007554|ref|NP_081293.4|/9.73577e-73/zinc finger protein family member [Mus musculus] 242408 1763 0.116666667 0.24 1.040641984 Up 0.215239385 Fam221b "family with sequence similarity 221, member B" K04573|1|7e-08|61.6|oaa:100077333|neurofilament medium polypeptide (neurofilament 3) - - - gi|30425280|ref|NP_780726.1|/0/protein FAM221B [Mus musculus] 100647 2036 0.12 0.24 1 Up 0.215239385 Upk3b uroplakin 3B K17630|1|4e-24|115|fpg:101924060|Ras GTPase-activating protein 4;K19520|2|2e-14|84.0|rro:104665946|uroplakin-3a - - - - 72154 5304 0.85 0.66 -0.364996817 Down 0.21522058 Zfp157 zinc finger protein 157 K09228|1|0.0|1224|mmu:72154|KRAB domain-containing zinc finger protein - GO:0043169//cation binding GO:0045165//cell fate commitment;GO:0022612//gland morphogenesis;GO:0030324//lung development "gi|148687243|gb|EDL19190.1|/0/RIKEN cDNA 2610020C11, isoform CRA_a, partial [Mus musculus]" 73652 749.68 21.73333333 22.97333333 0.080050737 Up 0.215173568 2210408F21Rik RIKEN cDNA 2210408F21 gene - - - - "gi|148681769|gb|EDL13716.1|/1.78431e-35/mCG4750, isoform CRA_b [Mus musculus]" 231070 2667 7.49 6.95 -0.107952741 Down 0.215098349 Insig1 insulin induced gene 1 - GO:0030176//integral component of endoplasmic reticulum membrane GO:0005488//binding GO:0006984//ER-nucleus signaling pathway;GO:0032868//response to insulin;GO:0097094//craniofacial suture morphogenesis;GO:0006639//acylglycerol metabolic process;GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0043627//response to estrogen;GO:0045444//fat cell differentiation;GO:0006633//fatty acid biosynthetic process;GO:0031333//negative regulation of protein complex assembly;GO:0042471//ear morphogenesis;GO:0006950//response to stress gi|23943846|ref|NP_705746.1|/1.96948e-140/insulin-induced gene 1 protein [Mus musculus] 72238 5649.65 7.386666667 6.843333333 -0.110224254 Down 0.215098349 Tbc1d5 "TBC1 domain family, member 5" K18469|1|0.0|1445|mmu:72238|TBC1 domain family member 5 - - - gi|60359914|dbj|BAD90176.1|/0/mKIAA0210 protein [Mus musculus] 212276 4615 0.38 0.543333333 0.51583814 Up 0.215098349 Zfp748 zinc finger protein 748 K09228|1|0.0|1926|mmu:212276|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding - gi|60360632|dbj|BAD90328.1|/0/mKIAA4236 protein [Mus musculus] 72709 2376.55 7.113333333 7.653333333 0.105562466 Up 0.215098349 C1qtnf6 C1q and tumor necrosis factor related protein 6 K19470|1|1e-58|230|mmu:72709|complement C1q tumor necrosis factor-related protein 6 GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0051291//protein heterooligomerization;GO:0051291//protein heterooligomerization;GO:0051291//protein heterooligomerization gi|148540036|ref|NP_082607.3|/2.47425e-134/complement C1q tumor necrosis factor-related protein 6 isoform 1 precursor [Mus musculus] 21802 4547 0.14 0.27 0.94753258 Up 0.215079544 Tgfa transforming growth factor alpha "K08774|1|5e-70|269|mmu:21802|transforming growth factor, alpha" - - - - 19361 2138 0.136666667 0.263333333 0.946228744 Up 0.215079544 Rad51 RAD51 recombinase K04482|1|0.0|639|mmu:19361|DNA repair protein RAD51 GO:0016604//nuclear body;GO:0000795//synaptonemal complex;GO:0044429 GO:0008094//DNA-dependent ATPase activity;GO:0032550;GO:0005515//protein binding;GO:0043566//structure-specific DNA binding GO:0042221//response to chemical;GO:0007127//meiosis I;GO:0006261//DNA-dependent DNA replication;GO:0000725//recombinational repair;GO:0051259//protein oligomerization;GO:0006266//DNA ligation gi|6755276|ref|NP_035364.1|/0/DNA repair protein RAD51 homolog 1 [Mus musculus] 20680 3266 13.88666667 13.04666667 -0.090019083 Down 0.21498552 Sox7 SRY (sex determining region Y)-box 7 K09270|1|0.0|714|mmu:20680|transcription factor SOX7/8/10/18 (SOX group E/F) GO:0043231//intracellular membrane-bounded organelle "GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000975//regulatory region DNA binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0030111//regulation of Wnt signaling pathway;GO:0001704//formation of primary germ layer gi|6755612|ref|NP_035576.1|/0/transcription factor SOX-7 [Mus musculus] 67439 2654 13.13333333 13.97666667 0.089787201 Up 0.21498552 Xab2 XPA binding protein 2 K12867|1|0.0|1622|mmu:67439|pre-mRNA-splicing factor SYF1 GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen GO:0005488//binding GO:0006289//nucleotide-excision repair;GO:0000377;GO:0001701//in utero embryonic development gi|13385660|ref|NP_080432.1|/0/pre-mRNA-splicing factor SYF1 [Mus musculus] 71770 5397.49 13.74333333 12.90666667 -0.090615509 Down 0.21498552 Ap2b1 "adaptor-related protein complex 2, beta 1 subunit" K11825|1|0.0|1731|mmu:71770|AP-2 complex subunit beta-1 GO:0030119//AP-type membrane coat adaptor complex;GO:0030665//clathrin-coated vesicle membrane;GO:0030139//endocytic vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0030665//clathrin-coated vesicle membrane;GO:0030139//endocytic vesicle GO:0005515//protein binding;GO:0022892//substrate-specific transporter activity;GO:0005515//protein binding;GO:0022892//substrate-specific transporter activity GO:0007267//cell-cell signaling;GO:0006901//vesicle coating;GO:0015031//protein transport;GO:0044764;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0050688//regulation of defense response to virus;GO:0006935//chemotaxis;GO:0002478;GO:0007267//cell-cell signaling;GO:0006901//vesicle coating;GO:0015031//protein transport;GO:0044764;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0050688//regulation of defense response to virus;GO:0006935//chemotaxis;GO:0002478 gi|21313640|ref|NP_082191.1|/0/AP-2 complex subunit beta isoform b [Mus musculus] 66753 3501 13.00666667 13.85 0.090634699 Up 0.21498552 Erlec1 endoplasmic reticulum lectin 1 K14008|1|0.0|967|mmu:66753|endoplasmic reticulum lectin 1 GO:0044432 GO:0005515//protein binding GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process gi|12832479|dbj|BAB22125.1|/0/unnamed protein product [Mus musculus] 20224 2602 66.46 69.90666667 0.072943752 Up 0.214966716 Sar1a secretion associated Ras related GTPase 1A K07953|1|3e-110|402|pale:102892107|GTP-binding protein SAR1 [EC:3.6.5.-] GO:0005783//endoplasmic reticulum GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0009154//purine ribonucleotide catabolic process;GO:0016482//cytosolic transport;GO:0015031//protein transport gi|21703344|ref|NP_033146.1|/2.28125e-109/GTP-binding protein SAR1a [Mus musculus] 68552 2084 20.43 21.66333333 0.084566043 Up 0.214966716 Smim14 small integral membrane protein 14 - GO:0031224//intrinsic component of membrane - - gi|19526868|ref|NP_598458.1|/1.27172e-51/small integral membrane protein 14 [Mus musculus] 414111 2071 0.276666667 0.423333333 0.613645255 Up 0.214929106 C130083M11Rik RIKEN cDNA C130083M11 gene - - - - "gi|148705706|gb|EDL37653.1|/2.01544e-49/mCG144984, partial [Mus musculus]" 17960 1347 0.293333333 0.446666667 0.606657572 Up 0.214929106 Nat1 N-acetyl transferase 1 K00622|1|1e-167|591|mmu:17960|arylamine N-acetyltransferase [EC:2.3.1.5] GO:0044444//cytoplasmic part GO:0008080//N-acetyltransferase activity;GO:0045182//translation regulator activity GO:0006412//translation;GO:0044767//single-organism developmental process;GO:0014070//response to organic cyclic compound;GO:0002237//response to molecule of bacterial origin gi|755525833|ref|XP_006509654.2|/6.06746e-168/PREDICTED: arylamine N-acetyltransferase 1 isoform X1 [Mus musculus] 69482 2732 1.573333333 1.33 -0.242398113 Down 0.214863289 Nup35 nucleoporin 35 K14313|1|0.0|643|mmu:69482|nuclear pore complex protein Nup53 GO:0005856//cytoskeleton;GO:0016021//integral component of membrane;GO:0031981//nuclear lumen;GO:0005635//nuclear envelope;GO:0005856//cytoskeleton;GO:0016021//integral component of membrane;GO:0031981//nuclear lumen;GO:0005635//nuclear envelope GO:0042802//identical protein binding;GO:0022829//wide pore channel activity;GO:0042802//identical protein binding;GO:0022829//wide pore channel activity GO:0044763;GO:0050658//RNA transport;GO:0045184//establishment of protein localization;GO:0044763;GO:0050658//RNA transport;GO:0045184//establishment of protein localization gi|58037163|ref|NP_081367.1|/1.03361e-176/nucleoporin NUP53 isoform 1 [Mus musculus] 231506 4464 1.53 1.293333333 -0.242437501 Down 0.214863289 Lin54 lin-54 homolog (C. elegans) K10955|1|4e-08|63.9|gga:423101|intestinal mucin-2 GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0007049//cell cycle;GO:0006351//transcription, DNA-templated;GO:0044763;GO:0006351//transcription, DNA-templated" gi|60359862|dbj|BAD90150.1|/0/mKIAA2037 protein [Mus musculus] 110948 4833 1.35 1.59 0.236067358 Up 0.214863289 Hlcs holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) K01942|1|0.0|1370|mmu:110948|biotin--protein ligase [EC:6.3.4.9 6.3.4.10 6.3.4.11 6.3.4.15] GO:0044427;GO:0034399//nuclear periphery;GO:0044444//cytoplasmic part GO:0019842//vitamin binding;GO:0032550;GO:0042802//identical protein binding;GO:0018271//biotin-protein ligase activity GO:0010243//response to organonitrogen compound;GO:0044699;GO:0009305//protein biotinylation gi|568997162|ref|XP_006522914.1|/0/PREDICTED: biotin--protein ligase isoform X2 [Mus musculus] 100040462 1930 9.143333333 8.516666667 -0.102431331 Down 0.214844485 Mndal myeloid nuclear differentiation antigen like K12971|1|6e-53|211|mmu:26388|interferon-activable protein 202;K12966|5|5e-36|155|ecb:100057148|absent in melanoma 2 GO:0016604//nuclear body "GO:0005515//protein binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0043566//structure-specific DNA binding" GO:0031348//negative regulation of defense response;GO:0002253//activation of immune response;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0032611//interleukin-1 beta production;GO:0010951//negative regulation of endopeptidase activity;GO:0043583//ear development;GO:0072331//signal transduction by p53 class mediator;GO:0002573//myeloid leukocyte differentiation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0019079//viral genome replication;GO:0051100//negative regulation of binding;GO:0002252;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0010212//response to ionizing radiation;GO:0016049//cell growth;GO:0009267//cellular response to starvation;GO:0035456//response to interferon-beta gi|283046753|ref|NP_001164324.1|/0/myeloid cell nuclear differentiation antigen-like protein [Mus musculus] 108013 2536.99 0.553333333 0.736666667 0.412863128 Up 0.214835082 Celf4 "CUGBP, Elav-like family member 4" K13207|1|0.0|727|mmu:108013|CUG-BP- and ETR3-like factor GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0030371//translation repressor activity;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0030371//translation repressor activity;GO:0036094//small molecule binding;GO:0003723//RNA binding "GO:0000245//spliceosomal complex assembly;GO:0045837//negative regulation of membrane potential;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007275//multicellular organism development;GO:0003006//developmental process involved in reproduction;GO:0045837//negative regulation of membrane potential;GO:0000245//spliceosomal complex assembly;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0045837//negative regulation of membrane potential;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007275//multicellular organism development;GO:0003006//developmental process involved in reproduction;GO:0045837//negative regulation of membrane potential;GO:0000245//spliceosomal complex assembly;GO:0000380//alternative mRNA splicing, via spliceosome" gi|507616395|ref|XP_004623667.1|/0/PREDICTED: CUGBP Elav-like family member 4 isoform X14 [Octodon degus] 12465 1769 68.05 71.44 0.070136919 Up 0.214797473 Cct5 "chaperonin containing Tcp1, subunit 5 (epsilon)" K09497|1|0.0|1015|mmu:12465|T-complex protein 1 subunit epsilon GO:0005815//microtubule organizing center;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0032550;GO:0005515//protein binding GO:0051707//response to other organism;GO:0035036//sperm-egg recognition;GO:0006458//'de novo' protein folding gi|37359776|dbj|BAC97866.1|/0/mKIAA0098 protein [Mus musculus] 319317 5864 0.203333333 0.343333333 0.75576319 Up 0.214759863 Snhg11 small nucleolar RNA host gene 11 - - - - gi|26348733|dbj|BAC38006.1|/1.28856e-54/unnamed protein product [Mus musculus] 78619 3756 1.123333333 0.91 -0.30384764 Down 0.214722254 Zfp449 zinc finger protein 449 K09230|1|0.0|1036|cge:100764457|SCAN domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0044764;GO:0006351//transcription, DNA-templated" gi|625192244|ref|XP_003499868.2|/0/PREDICTED: zinc finger protein 449 isoform X1 [Cricetulus griseus] 232560 3535.64 0.896666667 1.103333333 0.299225044 Up 0.214722254 Caprin2 caprin family member 2 K18744|1|0.0|1174|cge:100762439|caprin-2 - - - - 237775 3412 2.903333333 2.583333333 -0.168476408 Down 0.214712851 Zfp867 zinc finger protein 867 K09228|1|0.0|1004|mmu:237775|KRAB domain-containing zinc finger protein GO:0044464 GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|266456486|ref|NP_848504.2|/0/zinc finger protein 867 [Mus musculus] 75146 2280 2.553333333 2.87 0.168668845 Up 0.214712851 Tmem180 major facilitator superfamily domain containing 13a - GO:0031224//intrinsic component of membrane - - gi|114051517|ref|NP_083462.2|/0/transmembrane protein 180 [Mus musculus] 14585 4495 2.88 2.556666667 -0.171804735 Down 0.214712851 Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 K19895|1|0.0|924|mmu:14585|GDNF family receptor alpha 1 GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0009986//cell surface;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0009986//cell surface;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0009986//cell surface;GO:0044421 GO:0005102//receptor binding;GO:0005102//receptor binding;GO:0005102//receptor binding GO:0030030//cell projection organization;GO:0048870//cell motility;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0030154//cell differentiation;GO:0008406//gonad development;GO:0030030//cell projection organization;GO:0048870//cell motility;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0030154//cell differentiation;GO:0008406//gonad development;GO:0030030//cell projection organization;GO:0048870//cell motility;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0030154//cell differentiation;GO:0008406//gonad development gi|6753976|ref|NP_034409.1|/0/GDNF family receptor alpha-1 isoform 1 precursor [Mus musculus] 17977 7346 4.76 4.343333333 -0.132158895 Down 0.214703449 Ncoa1 nuclear receptor coactivator 1 K09101|1|0.0|2340|mmu:17977|nuclear receptor coactivator 1 [EC:2.3.1.48] GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0000785//chromatin GO:0060089;GO:0042974//retinoic acid receptor binding;GO:0035258//steroid hormone receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0003713//transcription coactivator activity;GO:0008080//N-acetyltransferase activity GO:0006915//apoptotic process;GO:0008406//gonad development;GO:0022037//metencephalon development;GO:0000411//positive regulation of transcription by galactose;GO:0021543//pallium development;GO:0007589//body fluid secretion;GO:0021536//diencephalon development;GO:0030182//neuron differentiation;GO:0043627//response to estrogen;GO:0022602//ovulation cycle process;GO:0016573//histone acetylation;GO:0035690//cellular response to drug;GO:0006366//transcription from RNA polymerase II promoter;GO:0045924//regulation of female receptivity gi|6754800|ref|NP_035011.1|/0/nuclear receptor coactivator 1 [Mus musculus] 12607 4091 4.733333333 4.316666667 -0.132938832 Down 0.214703449 Cebpz CCAAT/enhancer binding protein zeta K14832|1|0.0|1803|mmu:12607|ribosome biogenesis protein MAK21 - - - gi|67188876|ref|NP_001019977.1|/0/CCAAT/enhancer-binding protein zeta [Mus musculus] 23856 7498.15 4.756666667 4.336666667 -0.133364373 Down 0.214703449 Dido1 death inducer-obliterator 1 K04257|1|3e-16|91.3|ocu:100350309|olfactory receptor;K14960|2|6e-15|86.7|aag:AaeL_AAEL011688|COMPASS component SPP1;K11728|5|3e-12|77.8|api:100165264|nucleosome-remodeling factor subunit BPTF GO:0044424;GO:0044424 GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0010467//gene expression;GO:0012501//programmed cell death;GO:0010467//gene expression;GO:0012501//programmed cell death gi|37359898|dbj|BAC97927.1|/0/mKIAA0333 protein [Mus musculus] 99151 2715 2.88 3.223333333 0.162484577 Up 0.214581218 Cercam cerebral endothelial cell adhesion molecule "K11703|1|0.0|729|lcm:102352198|collagen beta-1,O-galactosyltransferase [EC:2.4.1.50]" GO:0043231//intracellular membrane-bounded organelle - GO:0008610//lipid biosynthetic process;GO:0022610 gi|46411176|ref|NP_997181.1|/0/probable inactive glycosyltransferase 25 family member 3 precursor [Mus musculus] 75614 295 0.556666667 0.733333333 0.397655421 Up 0.214581218 Rab26os "RAB26, member RAS oncogene family, opposite strand" - - - - - 78058 2140 0.2 0.336666667 0.751320887 Up 0.214581218 4930578E11Rik RIKEN cDNA 4930578E11 gene - - - - - 15288 1611 22.45 23.66 0.075734629 Up 0.214553011 Hmbs hydroxymethylbilane synthase K01749|1|0.0|705|mmu:15288|hydroxymethylbilane synthase [EC:2.5.1.61] GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome "GO:0048037//cofactor binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0043168//anion binding;GO:0016836//hydro-lyase activity;GO:0048037//cofactor binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0043168//anion binding;GO:0016836//hydro-lyase activity" GO:0014075//response to amine;GO:0007417//central nervous system development;GO:0046677//response to antibiotic;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0071385//cellular response to glucocorticoid stimulus;GO:0046685//response to arsenic-containing substance;GO:0043627//response to estrogen;GO:0018065//protein-cofactor linkage;GO:0034097//response to cytokine;GO:0001101//response to acid chemical;GO:0009887//organ morphogenesis;GO:0010288//response to lead ion;GO:0007584//response to nutrient;GO:0014075//response to amine;GO:0007417//central nervous system development;GO:0046677//response to antibiotic;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0071385//cellular response to glucocorticoid stimulus;GO:0046685//response to arsenic-containing substance;GO:0043627//response to estrogen;GO:0018065//protein-cofactor linkage;GO:0034097//response to cytokine;GO:0001101//response to acid chemical;GO:0009887//organ morphogenesis;GO:0010288//response to lead ion;GO:0007584//response to nutrient gi|387506|gb|AAA39890.1|/0/porphobilinogen deaminase (housekeeping) [Mus musculus] 218544 2719 0.453333333 0.3 -0.595609745 Down 0.214534206 Sgtb "small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta" K16365|1|2e-85|319|lcm:102357264|small glutamine-rich tetratricopeptide repeat-containing protein alpha - GO:0031072//heat shock protein binding - gi|21450231|ref|NP_659087.1|/1.63399e-158/small glutamine-rich tetratricopeptide repeat-containing protein beta [Mus musculus] 100043462 917 68.37 71.64 0.067401912 Up 0.214496596 Nutf2-ps1 "nuclear transport factor 2, pseudogene 1" K14285|1|2e-10|68.6|dgr:Dgri_GH13218|NTF2-related export protein 1/2 GO:0005856//cytoskeleton;GO:0005635//nuclear envelope;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0022892//substrate-specific transporter activity GO:0006886//intracellular protein transport gi|594689477|ref|XP_007192124.1|/6.24212e-76/PREDICTED: nuclear transport factor 2-like [Balaenoptera acutorostrata scammoni] 239618 3956 0.146666667 0.28 0.932885804 Up 0.214468389 Pdzrn4 PDZ domain containing RING finger 4 K15682|1|0.0|1300|mmu:239618|ligand of Numb protein X 3/4 [EC:2.3.2.27] - GO:0046914//transition metal ion binding - gi|257196168|ref|NP_001158065.1|/0/PDZ domain-containing RING finger protein 4 isoform 1 [Mus musculus] 233056 4525 2.09 1.813333333 -0.204858792 Down 0.214449584 Zfp790 zinc finger protein 790 K09228|1|0.0|1648|mmu:233056|KRAB domain-containing zinc finger protein - GO:0043169//cation binding;GO:0043169//cation binding - gi|225007589|ref|NP_666297.2|/0/zinc finger protein 790 [Mus musculus] 74019 3521 2.38 2.093333333 -0.185159515 Down 0.21443078 Traf3ip1 TRAF3 interacting protein 1 K19680|1|5e-179|631|mmu:74019|TRAF3-interacting protein 1 GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part GO:0015631//tubulin binding GO:0042505;GO:0051098//regulation of binding gi|63147418|ref|NP_082994.1|/4.26191e-178/TRAF3-interacting protein 1 [Mus musculus] 68895 1126 2.043333333 2.33 0.189405382 Up 0.21443078 Rasl11a "RAS-like, family 11, member A" K07852|1|2e-128|461|mmu:68895|Ras-like protein family member 11A GO:0031981//nuclear lumen GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0009154//purine ribonucleotide catabolic process;GO:0006360//transcription from RNA polymerase I promoter;GO:0035556//intracellular signal transduction gi|564378145|ref|XP_006248896.1|/1.99815e-133/PREDICTED: ras-like protein family member 11A isoform X1 [Rattus norvegicus] 317758 1383 2.12 2.413333333 0.186962932 Up 0.21443078 Gimap9 "GTPase, IMAP family member 9" - - - - "gi|28144914|ref|NP_777620.1|/1.59816e-163/GTPase, IMAP family member 9 [Mus musculus]" 215819 7025.4 2.296666667 2.01 -0.192345981 Down 0.21443078 Nhsl1 NHS-like 1 - - - - gi|124378008|ref|NP_775566.3|/0/NHS-like protein 1 isoform 1 [Mus musculus] 19276 4688 0.46 0.306666667 -0.584962501 Down 0.214421377 Ptprn2 "protein tyrosine phosphatase, receptor type, N polypeptide 2" K07817|1|0.0|1833|mmu:19276|receptor-type tyrosine-protein phosphatase N [EC:3.1.3.48] GO:0030133//transport vesicle;GO:0044432;GO:0031224//intrinsic component of membrane;GO:0033267 GO:0004721//phosphoprotein phosphatase activity;GO:0005488//binding GO:0043087//regulation of GTPase activity;GO:0006470//protein dephosphorylation gi|226052731|ref|NP_035345.2|/0/receptor-type tyrosine-protein phosphatase N2 precursor [Mus musculus] 72320 2535 20.76333333 21.96 0.080839983 Up 0.214308549 Kif1bp KIF1 binding protein K16911|1|0.0|766|apla:101794908|ATP-dependent RNA helicase DDX21 [EC:3.6.4.13] - - - - 56043 1729 12.2 13.02333333 0.094217607 Up 0.214270939 Akr1e1 "aldo-keto reductase family 1, member E1" "K13981|1|1e-176|622|mmu:56043|1,5-anhydro-D-fructose reductase [EC:1.1.1.263]" - "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0044710 "gi|93277108|ref|NP_061347.2|/1.10148e-175/1,5-anhydro-D-fructose reductase [Mus musculus]" 17128 3361 14.27333333 13.45333333 -0.085358621 Down 0.214270939 Smad4 SMAD family member 4 K04501|1|0.0|1040|mmu:17128|mothers against decapentaplegic homolog 4 GO:0005667//transcription factor complex;GO:0005815//microtubule organizing center "GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0005072//transforming growth factor beta receptor, cytoplasmic mediator activity" GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007184//SMAD protein import into nucleus;GO:0007369//gastrulation;GO:0048732//gland development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0043009//chordate embryonic development;GO:0072075//metanephric mesenchyme development;GO:0001942//hair follicle development;GO:0016049//cell growth;GO:0009895;GO:0001837//epithelial to mesenchymal transition;GO:0032906;GO:0001934//positive regulation of protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0065009;GO:0006935//chemotaxis;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030182//neuron differentiation;GO:0008219//cell death;GO:0072076//nephrogenic mesenchyme development;GO:0000578//embryonic axis specification;GO:0008283//cell proliferation;GO:0003002//regionalization;GO:0006950//response to stress gi|31543224|ref|NP_032566.2|/0/mothers against decapentaplegic homolog 4 [Mus musculus] 271005 1949 13.05666667 12.23333333 -0.093969065 Down 0.214270939 Klhdc1 kelch domain containing 1 K12562|1|7e-30|134|nve:NEMVE_v1g246594|amphiphysin;K10317|3|1e-22|110|nve:NEMVE_v1g100198|F-box protein 42;K20285|5|1e-18|97.4|lve:103073207|Rab9 effector protein with kelch motifs GO:0044424 - - gi|30142701|ref|NP_839984.1|/0/kelch domain-containing protein 1 [Mus musculus] 26381 5374 7.116666667 6.583333333 -0.112383417 Down 0.214261537 Esrrg estrogen-related receptor gamma K08554|1|0.0|892|ecb:100050530|estrogen-related receptor gamma GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0046914//transition metal ion binding;GO:0008289//lipid binding;GO:0003677//DNA binding;GO:0019904//protein domain specific binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0046914//transition metal ion binding;GO:0008289//lipid binding;GO:0003677//DNA binding;GO:0019904//protein domain specific binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding" GO:0030522//intracellular receptor signaling pathway;GO:0009755//hormone-mediated signaling pathway;GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter;GO:0030522//intracellular receptor signaling pathway;GO:0009755//hormone-mediated signaling pathway;GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter gi|6753774|ref|NP_036065.1|/0/estrogen-related receptor gamma isoform1 [Mus musculus] 227377 3929 6.843333333 7.376666667 0.108269824 Up 0.214261537 Farp2 "FERM, RhoGEF and pleckstrin domain protein 2" "K06082|1|0.0|1930|mmu:227377|FERM, RhoGEF and pleckstrin domain protein 2" GO:0043232;GO:0044425;GO:0044444//cytoplasmic part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0005515//protein binding GO:0019222//regulation of metabolic process;GO:0006935//chemotaxis;GO:0042551//neuron maturation;GO:0007266//Rho protein signal transduction "gi|229892332|ref|NP_663494.2|/0/FERM, RhoGEF and pleckstrin domain-containing protein 2 [Mus musculus]" 71745 4158 6.926666667 7.456666667 0.106369602 Up 0.214261537 Cul2 cullin 2 K03870|1|0.0|1463|mmu:71745|cullin 2 GO:0031981//nuclear lumen;GO:0000153//cytoplasmic ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex GO:0044389//ubiquitin-like protein ligase binding GO:0044772//mitotic cell cycle phase transition;GO:0008283//cell proliferation;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0001666//response to hypoxia;GO:0032446//protein modification by small protein conjugation;GO:0019941//modification-dependent protein catabolic process;GO:0035556//intracellular signal transduction gi|60359986|dbj|BAD90212.1|/0/mKIAA4106 protein [Mus musculus] 67912 2602.7 5.44 5.896666667 0.116292991 Up 0.214252134 1600012H06Rik RIKEN cDNA 1600012H06 gene K10848|1|3e-20|103|hst:105188485|DNA excision repair protein ERCC-4 [EC:3.1.-.-] - - GO:0012501//programmed cell death;GO:0012501//programmed cell death;GO:0012501//programmed cell death;GO:0012501//programmed cell death "gi|28175340|gb|AAH43303.1|/2.67019e-99/RIKEN cDNA 1600012H06 gene, partial [Mus musculus]" 15951 2302 5.33 5.79 0.119427815 Up 0.214252134 Ifi204 interferon activated gene 204 K12971|1|1e-109|399|mmu:26388|interferon-activable protein 202;K12966|3|4e-40|169|ecb:100057148|absent in melanoma 2 GO:0016604//nuclear body "GO:0005515//protein binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0043566//structure-specific DNA binding" GO:0031348//negative regulation of defense response;GO:0002253//activation of immune response;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0032611//interleukin-1 beta production;GO:0010951//negative regulation of endopeptidase activity;GO:0043583//ear development;GO:0072331//signal transduction by p53 class mediator;GO:0002573//myeloid leukocyte differentiation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0019079//viral genome replication;GO:0051100//negative regulation of binding;GO:0002252;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0010212//response to ionizing radiation;GO:0009267//cellular response to starvation;GO:0035456//response to interferon-beta gi|118130979|ref|NP_032355.2|/0/interferon-activable protein 204 [Mus musculus] 67883 1263 5.856666667 5.4 -0.117120378 Down 0.214252134 Uxs1 UDP-glucuronate decarboxylase 1 K08678|1|0.0|821|mmu:67883|UDP-glucuronate decarboxylase [EC:4.1.1.35] GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane GO:0036094//small molecule binding;GO:0016831//carboxy-lyase activity;GO:0048037//cofactor binding GO:0009226//nucleotide-sugar biosynthetic process gi|28076899|ref|NP_080706.1|/0/UDP-glucuronic acid decarboxylase 1 [Mus musculus] 76273 2391.95 5.466666667 5.93 0.117370696 Up 0.214252134 Ndfip2 Nedd4 family interacting protein 2 - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane - GO:0051049//regulation of transport;GO:0043170;GO:0007165//signal transduction;GO:0051049//regulation of transport;GO:0043170;GO:0007165//signal transduction gi|300360478|ref|NP_083837.2|/1.55352e-112/NEDD4 family-interacting protein 2 [Mus musculus] 76577 4322 5.353333333 5.81 0.118100677 Up 0.214252134 Faf2 Fas associated factor family member 2 K18726|1|0.0|833|ngi:103745397|FAS-associated factor 2 GO:0005789//endoplasmic reticulum membrane GO:0032182//ubiquitin-like protein binding;GO:0044389//ubiquitin-like protein ligase binding GO:0035966//response to topologically incorrect protein gi|674076364|ref|XP_008845544.1|/0/PREDICTED: FAS-associated factor 2 [Nannospalax galili] 102466257 111 66.16 69.31333333 0.067173666 Up 0.214139306 Mir8114 microRNA 8114 - - - - - 57905 1620 8.3 8.923333333 0.104471397 Up 0.214129903 Isy1 ISY1 splicing factor homolog K12870|1|3e-140|501|mcf:102136056|pre-mRNA-splicing factor ISY1 - - - - 100041151 1739 0.466666667 0.633333333 0.440572591 Up 0.214129903 Gm3636 predicted gene 3636 "K03844|1|4e-17|92.4|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - - 217700 1822 1.07 1.293333333 0.273483355 Up 0.214092294 Acot6 acyl-CoA thioesterase 6 K11993|1|0.0|830|mmu:217700|acyl-CoA thioesterase 6 [EC:3.1.2.-] GO:0042579//microbody "GO:0016788//hydrolase activity, acting on ester bonds" GO:0006732 gi|110626167|ref|NP_766168.1|/0/acyl-coenzyme A thioesterase 6 [Mus musculus] 241944 6625 1.083333333 1.303333333 0.266728889 Up 0.214092294 D3Ertd254e "DNA segment, Chr 3, ERATO Doi 254, expressed" K09228|1|0.0|753|hgl:101723100|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|157951711|ref|NP_001094948.1|/0/uncharacterized protein LOC241944 [Mus musculus] 12757 1119.6 61.6 64.73333333 0.071578444 Up 0.214064087 Clta "clathrin, light polypeptide (Lca)" K04644|1|3e-103|377|ocu:100350456|clathrin light chain A GO:0005802//trans-Golgi network;GO:0012510//trans-Golgi network transport vesicle membrane;GO:0005905//clathrin-coated pit;GO:0030118//clathrin coat;GO:0005802//trans-Golgi network;GO:0012510//trans-Golgi network transport vesicle membrane;GO:0005905//clathrin-coated pit;GO:0030118//clathrin coat;GO:0005802//trans-Golgi network;GO:0012510//trans-Golgi network transport vesicle membrane;GO:0005905//clathrin-coated pit;GO:0030118//clathrin coat;GO:0012510//trans-Golgi network transport vesicle membrane;GO:0005905//clathrin-coated pit;GO:0030117//membrane coat GO:0033218//amide binding;GO:0033218//amide binding;GO:0033218//amide binding;GO:0033218//amide binding GO:0015031//protein transport;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048193//Golgi vesicle transport;GO:0006935//chemotaxis;GO:0002478;GO:0015031//protein transport;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048193//Golgi vesicle transport;GO:0006935//chemotaxis;GO:0002478;GO:0015031//protein transport;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048193//Golgi vesicle transport;GO:0006935//chemotaxis;GO:0002478;GO:0015031//protein transport gi|594190913|ref|NP_001277399.1|/9.889e-102/clathrin light chain A isoform e [Mus musculus] 22318 2164 65.45 68.51333333 0.065991585 Up 0.21396066 Vamp2 vesicle-associated membrane protein 2 K13504|1|4e-33|145|pbi:103050427|vesicle-associated membrane protein 2 GO:0030658//transport vesicle membrane;GO:0016021//integral component of membrane;GO:0030665//clathrin-coated vesicle membrane;GO:0030139//endocytic vesicle;GO:0030667//secretory granule membrane;GO:0008021//synaptic vesicle;GO:0042995//cell projection;GO:0031201//SNARE complex GO:0008092//cytoskeletal protein binding;GO:0008289//lipid binding;GO:0019905//syntaxin binding GO:0015980//energy derivation by oxidation of organic compounds;GO:0032868//response to insulin;GO:0032388//positive regulation of intracellular transport;GO:0006835//dicarboxylic acid transport;GO:0006887//exocytosis;GO:0006886//intracellular protein transport;GO:0048193//Golgi vesicle transport;GO:0065003;GO:0030073//insulin secretion;GO:0009746;GO:0001505//regulation of neurotransmitter levels gi|972956729|ref|XP_015196049.1|/3.07213e-32/PREDICTED: vesicle-associated membrane protein 2 isoform X1 [Lepisosteus oculatus] 22404 4014.75 13.27333333 14.08 0.085116614 Up 0.213904246 Wiz widely-interspaced zinc finger motifs - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - "gi|148708371|gb|EDL40318.1|/0/mCG14253, isoform CRA_c, partial [Mus musculus]" 227120 6555 0.746666667 0.57 -0.389502407 Down 0.213876039 Plcl1 phospholipase C-like 1 K15375|1|0.0|1974|mmu:227120|inactive phospholipase C-like protein 1 GO:0044424 GO:0060089;GO:0046872//metal ion binding;GO:0008289//lipid binding;GO:0004629//phospholipase C activity GO:0007165//signal transduction;GO:0044238//primary metabolic process gi|167900458|ref|NP_001108135.1|/0/inactive phospholipase C-like protein 1 [Mus musculus] 21930 1601 0.67 0.856666667 0.354572858 Up 0.213838429 Tnfaip6 tumor necrosis factor alpha induced protein 6 K19018|1|1e-160|568|mmu:21930|tumor necrosis factor-inducible gene 6 protein - GO:0005539//glycosaminoglycan binding GO:0022610 gi|6678379|ref|NP_033424.1|/1.00307e-159/tumor necrosis factor-inducible gene 6 protein precursor [Mus musculus] 20288 2377.32 0.676666667 0.863333333 0.351472371 Up 0.213838429 Msr1 macrophage scavenger receptor 1 K06558|1|1e-170|603|mmu:20288|macrophage scavenger receptor 1 GO:0034358//plasma lipoprotein particle;GO:0031224//intrinsic component of membrane;GO:0031982//vesicle;GO:0044444//cytoplasmic part;GO:0005578//proteinaceous extracellular matrix;GO:0034358//plasma lipoprotein particle;GO:0031224//intrinsic component of membrane;GO:0031982//vesicle;GO:0044444//cytoplasmic part;GO:0005578//proteinaceous extracellular matrix GO:0071813//lipoprotein particle binding;GO:0071813//lipoprotein particle binding GO:0015918//sterol transport;GO:0006897//endocytosis;GO:0010742//macrophage derived foam cell differentiation;GO:0015031//protein transport;GO:0044707;GO:0010878//cholesterol storage;GO:0015918//sterol transport;GO:0006897//endocytosis;GO:0010742//macrophage derived foam cell differentiation;GO:0015031//protein transport;GO:0044707;GO:0010878//cholesterol storage gi|164664520|ref|NP_001106797.1|/0/macrophage scavenger receptor types I and II isoform b [Mus musculus] 66253 1054 22.46333333 21.29 -0.077396075 Down 0.213716198 Aig1 androgen-induced 1 - GO:0031224//intrinsic component of membrane - - gi|13384848|ref|NP_079722.1|/1.35206e-142/androgen-induced gene 1 protein [Mus musculus] 269604 4762 21.89333333 23.06333333 0.075109414 Up 0.213716198 Gpr157 G protein-coupled receptor 157 K08467|1|6e-153|545|mmu:269604|G protein-coupled receptor 157 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|74178472|dbj|BAE32492.1|/9.76231e-155/unnamed protein product [Mus musculus] 75602 751 0.533333333 0.376666667 -0.501749132 Down 0.213659784 1810062O18Rik RIKEN cDNA 1810062O18 gene K10591|1|9e-06|52.8|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] - GO:0016790//thiolester hydrolase activity GO:0019941//modification-dependent protein catabolic process "gi|148669557|gb|EDL01504.1|/7.28016e-74/mCG145865, partial [Mus musculus]" 319859 763 1.456666667 1.226666667 -0.247927513 Down 0.213575163 E030011O05Rik RIKEN cDNA E030011O05 gene - - - - - 211550 2164 1.236666667 1.47 0.249359469 Up 0.213575163 Tifa TRAF-interacting protein with forkhead-associated domain - - - - gi|21553067|ref|NP_660115.1|/4.80342e-102/TRAF-interacting protein with FHA domain-containing protein A [Mus musculus] 56399 3890.41 12.06666667 12.86666667 0.09261115 Up 0.213481139 Akap8 A kinase (PRKA) anchor protein 8 K16525|1|3e-142|509|mmu:56399|A-kinase anchor protein 8 GO:0045120//pronucleus;GO:0034399//nuclear periphery;GO:0005694//chromosome "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0051018//protein kinase A binding;GO:0046914//transition metal ion binding;GO:0043566//structure-specific DNA binding" GO:0000070//mitotic sister chromatid segregation;GO:0006796//phosphate-containing compound metabolic process gi|31560394|ref|NP_062748.2|/0/A-kinase anchor protein 8 [Mus musculus] 22642 3415 12.65666667 13.46 0.088780912 Up 0.213481139 Zbtb17 zinc finger and BTB domain containing 17 K10500|1|0.0|1548|mmu:22642|zinc finger and BTB domain-containing protein 17 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0009888//tissue development;GO:0007369//gastrulation;GO:0006351//transcription, DNA-templated" gi|171919772|ref|NP_033567.2|/0/zinc finger and BTB domain-containing protein 17 [Mus musculus] 71648 2413 62.87666667 65.81 0.065782085 Up 0.213471736 Optn optineurin K19946|1|0.0|1140|mmu:71648|optineurin GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0001025//RNA polymerase III transcription factor binding GO:0007030//Golgi organization;GO:0006886//intracellular protein transport;GO:0051259//protein oligomerization "gi|148676014|gb|EDL07961.1|/0/optineurin, isoform CRA_b, partial [Mus musculus]" 22146 1977 21.56666667 22.72666667 0.075582887 Up 0.213424725 Tuba1c "tubulin, alpha 1C" K07374|1|0.0|859|xla:100037141|tubulin alpha GO:0005874//microtubule GO:0005198//structural molecule activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0007010//cytoskeleton organization;GO:0006458//'de novo' protein folding;GO:0044765//single-organism transport;GO:0043623//cellular protein complex assembly;GO:0009154//purine ribonucleotide catabolic process;GO:0070670//response to interleukin-4 gi|795418245|ref|XP_011758519.1|/0/PREDICTED: tubulin alpha-1C chain [Macaca nemestrina] 69612 3589.91 21.00666667 22.16333333 0.077327623 Up 0.213424725 Kansl2 KAT8 regulatory NSL complex subunit 2 K18401|1|0.0|964|mmu:69612|KAT8 regulatory NSL complex subunit 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0043967//histone H4 acetylation;GO:0043967//histone H4 acetylation;GO:0043967//histone H4 acetylation;GO:0043967//histone H4 acetylation;GO:0043967//histone H4 acetylation gi|31981558|ref|NP_598475.2|/0/KAT8 regulatory NSL complex subunit 2 isoform a [Mus musculus] 12904 900 0.166666667 0.06 -1.473931188 Down 0.213424725 Crabp2 cellular retinoic acid binding protein II K17289|1|4e-74|280|mmu:12904|cellular retinoic acid-binding protein 2 GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0005501//retinoid binding "GO:0051234//establishment of localization;GO:0006351//transcription, DNA-templated;GO:0009888//tissue development;GO:0001523//retinoid metabolic process;GO:0030326//embryonic limb morphogenesis;GO:0007154//cell communication;GO:0016102//diterpenoid biosynthetic process;GO:0010876//lipid localization" gi|33469075|ref|NP_031785.1|/2.9644e-73/cellular retinoic acid-binding protein 2 [Mus musculus] 216971 3884 8.816666667 9.426666667 0.096514398 Up 0.21340592 Fam222b "family with sequence similarity 222, member B" - - - - - 211556 2391 8.836666667 8.223333333 -0.103778955 Down 0.21340592 Ap1ar adaptor-related protein complex 1 associated regulatory protein - "GO:0031981//nuclear lumen;GO:0005768//endosome;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0008092//cytoskeletal protein binding;GO:0032403//protein complex binding GO:0010771//negative regulation of cell morphogenesis involved in differentiation;GO:0045184//establishment of protein localization;GO:0040013//negative regulation of locomotion;GO:0034314//Arp2/3 complex-mediated actin nucleation gi|109659853|ref|NP_666076.2|/3.36128e-144/AP-1 complex-associated regulatory protein [Mus musculus] 20866 3609 9.296666667 8.69 -0.097357351 Down 0.21340592 Stim1 stromal interaction molecule 1 K16059|1|0.0|1157|mmu:20866|stromal interaction molecule 1 GO:0044448;GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0015630//microtubule cytoskeleton;GO:0016021//integral component of membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0005262//calcium channel activity;GO:0046872//metal ion binding;GO:0008017//microtubule binding;GO:0016247//channel regulator activity GO:0007599//hemostasis;GO:1901341//positive regulation of store-operated calcium channel activity;GO:0009593//detection of chemical stimulus gi|31981983|ref|NP_033313.2|/0/stromal interaction molecule 1 precursor [Mus musculus] 52477 3194.91 8.823333333 9.43 0.095933982 Up 0.21340592 Angel2 angel homolog 2 (Drosophila) K18729|1|0.0|794|mmu:52477|protein angel - - - gi|70794813|ref|NP_067396.3|/0/protein angel homolog 2 isoform 1 [Mus musculus] 53610 2467.76 54.24 57.12333333 0.074722989 Up 0.213396517 Nono "non-POU-domain-containing, octamer binding protein" K13214|1|0.0|663|mmu:53610|non-POU domain-containing octamer-binding protein GO:0016604//nuclear body;GO:0034399//nuclear periphery;GO:0016604//nuclear body;GO:0034399//nuclear periphery GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding "GO:0006396//RNA processing;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006351//transcription, DNA-templated;GO:0006396//RNA processing;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006351//transcription, DNA-templated" gi|74141990|dbj|BAE41058.1|/0/unnamed protein product [Mus musculus] 70383 2921 56.07666667 58.94666667 0.072009639 Up 0.213358908 Cox10 cytochrome c oxidase assembly protein 10 K02257|1|0.0|843|mmu:70383|protoheme IX farnesyltransferase [EC:2.5.1.-] GO:0031224//intrinsic component of membrane;GO:0005740//mitochondrial envelope GO:0004311//farnesyltranstransferase activity GO:0006996//organelle organization;GO:0006783//heme biosynthetic process;GO:0018342//protein prenylation;GO:0045333//cellular respiration;GO:0043623//cellular protein complex assembly "gi|30410008|ref|NP_848466.1|/0/protoheme IX farnesyltransferase, mitochondrial [Mus musculus]" 71122 1582 0.28 0.15 -0.900464326 Down 0.213358908 4933408N05Rik RIKEN cDNA 4933408N05 gene - - - - - 66457 1495 1.503333333 1.753333333 0.221935366 Up 0.213349505 2810002D19Rik RIKEN cDNA 2810002D19 gene - - - - - 223827 6534 1.533333333 1.783333333 0.21790503 Up 0.213349505 Gxylt1 glucoside xylosyltransferase 1 "K13676|1|0.0|731|mmu:223827|UDP-xylose:glucoside alpha-1,3-xylosyltransferase [EC:2.4.2.-]" GO:0031224//intrinsic component of membrane GO:0008194//UDP-glycosyltransferase activity GO:0006493//protein O-linked glycosylation gi|152125897|sp|Q3UHH8.2|GXLT1_MOUSE/0/RecName: Full=Glucoside xylosyltransferase 1; AltName: Full=Glycosyltransferase 8 domain-containing protein 3 51795 2456 1.766666667 1.52 -0.216958535 Down 0.213349505 Srpx sushi-repeat-containing protein K19408|1|2e-118|429|rno:317181|sushi repeat-containing protein SRPX2 GO:0005773//vacuole GO:0005488//binding GO:0006909//phagocytosis;GO:0008285//negative regulation of cell proliferation;GO:0006950//response to stress;GO:0044248;GO:0006915//apoptotic process gi|8394362|ref|NP_058607.1|/0/sushi-repeat-containing protein SRPX precursor [Mus musculus] 217082 5665 4.566666667 4.16 -0.134557959 Down 0.213321298 Hlf hepatic leukemia factor K09057|1|1e-138|498|mmu:217082|hepatic leukemia factor GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0043566//structure-specific DNA binding "GO:0007519//skeletal muscle tissue development;GO:0006351//transcription, DNA-templated" gi|31982951|ref|NP_766151.1|/9.48628e-138/hepatic leukemia factor [Mus musculus] 20133 3997 4.356666667 4.763333333 0.128746775 Up 0.213321298 Rrm1 ribonucleotide reductase M1 K10807|1|0.0|1528|mmu:20133|ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] GO:0044297//cell body;GO:0044424;GO:0043234//protein complex;GO:0012505//endomembrane system GO:0032550;GO:0000166//nucleotide binding;GO:0016728 GO:0043010//camera-type eye development;GO:0008406//gonad development;GO:0030900//forebrain development;GO:0006259//DNA metabolic process;GO:0009112;GO:0009314//response to radiation;GO:0009165//nucleotide biosynthetic process;GO:0051262//protein tetramerization gi|31982026|ref|NP_033129.2|/0/ribonucleoside-diphosphate reductase large subunit [Mus musculus] 56428 2596 56.97 54.11666667 -0.074129427 Down 0.213302494 Mtch2 mitochondrial carrier 2 K17885|1|2e-174|615|mmu:56428|mitochondrial carrier GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization "gi|148695555|gb|EDL27502.1|/0/mCG13498, isoform CRA_c, partial [Mus musculus]" 227331 5743 6.866666667 6.343333333 -0.114368776 Down 0.213302494 Gigyf2 GRB10 interacting GYF protein 2 K18730|1|0.0|1093|mmu:227331|PERQ amino acid-rich with GYF domain-containing protein - - GO:0006412//translation;GO:0050905//neuromuscular process;GO:0001894//tissue homeostasis;GO:0021515//cell differentiation in spinal cord;GO:0040007//growth;GO:0050879//multicellular organismal movement;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007626//locomotory behavior;GO:0044773//mitotic DNA damage checkpoint "gi|148708223|gb|EDL40170.1|/0/trinucleotide repeat containing 15, isoform CRA_g, partial [Mus musculus]" 19664 5587.67 6.303333333 6.823333333 0.114361739 Up 0.213302494 Rbpj recombination signal binding protein for immunoglobulin kappa J region K06053|1|0.0|1013|mmu:19664|recombining binding protein suppressor of hairless GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex "GO:0003824//catalytic activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding" "GO:0060842//arterial endothelial cell differentiation;GO:0006954//inflammatory response;GO:0003272//endocardial cushion formation;GO:0003157//endocardium development;GO:0030098//lymphocyte differentiation;GO:0008284//positive regulation of cell proliferation;GO:0060847//endothelial cell fate specification;GO:0006955//immune response;GO:0048732//gland development;GO:0009952//anterior/posterior pattern specification;GO:0001942//hair follicle development;GO:0009967//positive regulation of signal transduction;GO:0001503//ossification;GO:0042491//auditory receptor cell differentiation;GO:0006259//DNA metabolic process;GO:0000904//cell morphogenesis involved in differentiation;GO:0021536//diencephalon development;GO:0003137;GO:0030509//BMP signaling pathway;GO:0048771//tissue remodeling;GO:0032633//interleukin-4 production;GO:0010975//regulation of neuron projection development;GO:0035907//dorsal aorta development;GO:0030155//regulation of cell adhesion;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060379//cardiac muscle cell myoblast differentiation;GO:0003143//embryonic heart tube morphogenesis;GO:0040034//regulation of development, heterochronic;GO:0014909//smooth muscle cell migration;GO:0009913//epidermal cell differentiation;GO:0007368//determination of left/right symmetry;GO:0019827//stem cell population maintenance;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0048568//embryonic organ development;GO:0060842//arterial endothelial cell differentiation;GO:0006954//inflammatory response;GO:0003272//endocardial cushion formation;GO:0003157//endocardium development;GO:0030098//lymphocyte differentiation;GO:0008284//positive regulation of cell proliferation;GO:0060847//endothelial cell fate specification;GO:0006955//immune response;GO:0048732//gland development;GO:0009952//anterior/posterior pattern specification;GO:0001942//hair follicle development;GO:0009967//positive regulation of signal transduction;GO:0001503//ossification;GO:0042491//auditory receptor cell differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0021536//diencephalon development;GO:0003137;GO:0030509//BMP signaling pathway;GO:0048771//tissue remodeling;GO:0032633//interleukin-4 production;GO:0010975//regulation of neuron projection development;GO:0035907//dorsal aorta development;GO:0030155//regulation of cell adhesion;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060379//cardiac muscle cell myoblast differentiation;GO:0003143//embryonic heart tube morphogenesis;GO:0040034//regulation of development, heterochronic;GO:0014909//smooth muscle cell migration;GO:0009913//epidermal cell differentiation;GO:0007368//determination of left/right symmetry;GO:0019827//stem cell population maintenance;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0048568//embryonic organ development;GO:0060842//arterial endothelial cell differentiation;GO:0006954//inflammatory response;GO:0003272//endocardial cushion formation;GO:0003157//endocardium development;GO:0030098//lymphocyte differentiation;GO:0008284//positive regulation of cell proliferation;GO:0060847//endothelial cell fate specification;GO:0006955//immune response;GO:0048732//gland development;GO:0009952//anterior/posterior pattern specification;GO:0001942//hair follicle development;GO:0009967//positive regulation of signal transduction;GO:0001503//ossification;GO:0042491//auditory receptor cell differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0021536//diencephalon development;GO:0003137;GO:0030509//BMP signaling pathway;GO:0048771//tissue remodeling;GO:0032633//interleukin-4 production;GO:0010975//regulation of neuron projection development;GO:0035907//dorsal aorta development;GO:0030155//regulation of cell adhesion;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060379//cardiac muscle cell myoblast differentiation;GO:0003143//embryonic heart tube morphogenesis;GO:0040034//regulation of development, heterochronic;GO:0014909//smooth muscle cell migration;GO:0009913//epidermal cell differentiation;GO:0007368//determination of left/right symmetry;GO:0019827//stem cell population maintenance;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0048568//embryonic organ development;GO:0060842//arterial endothelial cell differentiation;GO:0006954//inflammatory response;GO:0003272//endocardial cushion formation;GO:0003157//endocardium development;GO:0030098//lymphocyte differentiation;GO:0008284//positive regulation of cell proliferation;GO:0060847//endothelial cell fate specification;GO:0006955//immune response;GO:0048732//gland development;GO:0009952//anterior/posterior pattern specification;GO:0001942//hair follicle development;GO:0009967//positive regulation of signal transduction;GO:0001503//ossification;GO:0042491//auditory receptor cell differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0021536//diencephalon development;GO:0003137;GO:0030509//BMP signaling pathway;GO:0048771//tissue remodeling;GO:0032633//interleukin-4 production;GO:0035907//dorsal aorta development;GO:0030155//regulation of cell adhesion;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060379//cardiac muscle cell myoblast differentiation;GO:0003143//embryonic heart tube morphogenesis;GO:0040034//regulation of development, heterochronic;GO:0009913//epidermal cell differentiation;GO:0007368//determination of left/right symmetry;GO:0019827//stem cell population maintenance;GO:0048568//embryonic organ development" gi|459683851|ref|NP_001264045.1|/0/recombining binding protein suppressor of hairless isoform 4 [Mus musculus] 223666 4587 2.546666667 2.243333333 -0.182966133 Down 0.213283689 Arhgap39 Rho GTPase activating protein 39 K20315|1|4e-13|80.5|pxy:105394249|Rho GTPase-activating protein 21/23;K10361|3|2e-11|74.7|lgi:LOTGIDRAFT_229291|myosin XV;K18470|5|4e-11|73.9|cfo:105248741|Rho GTPase-activating protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 - GO:0007154//cell communication;GO:0007154//cell communication gi|149066065|gb|EDM15938.1|/0/rCG59984 [Rattus norvegicus] 59053 1967 2.253333333 2.55 0.178436501 Up 0.213283689 Hgh1 HGH1 homolog - - - - gi|225903450|ref|NP_067530.2|/1.4392e-174/protein HGH1 homolog [Mus musculus] 20512 4214 0.283333333 0.153333333 -0.88582898 Down 0.213236677 Slc1a3 "solute carrier family 1 (glial high affinity glutamate transporter), member 3" "K05614|1|0.0|942|mmu:20512|solute carrier family 1 (glial high affinity glutamate transporter), member 3" GO:0044297//cell body;GO:0030425//dendrite;GO:0031224//intrinsic component of membrane;GO:0005578//proteinaceous extracellular matrix;GO:0019866//organelle inner membrane;GO:0044459 GO:0016597//amino acid binding;GO:0015291//secondary active transmembrane transporter activity;GO:0005313//L-glutamate transmembrane transporter activity GO:0009636//response to toxic substance;GO:0015813//L-glutamate transport;GO:0043090//amino acid import;GO:0050954//sensory perception of mechanical stimulus;GO:0008652//cellular amino acid biosynthetic process;GO:0000904//cell morphogenesis involved in differentiation;GO:0007638//mechanosensory behavior;GO:0001101//response to acid chemical;GO:0007268//chemical synaptic transmission;GO:0021675//nerve development;GO:0006536//glutamate metabolic process;GO:0009314//response to radiation;GO:0006950//response to stress;GO:0006814//sodium ion transport;GO:0022904//respiratory electron transport chain;GO:0050905//neuromuscular process gi|24233554|ref|NP_683740.1|/0/excitatory amino acid transporter 1 [Mus musculus] 69731 763 20.86 22.00666667 0.07720148 Up 0.213217872 Gemin7 gem (nuclear organelle) associated protein 7 K13135|1|8e-56|219|mmu:69731|gem associated protein 7 GO:0043234//protein complex;GO:0016604//nuclear body;GO:0044444//cytoplasmic part;GO:0030529//intracellular ribonucleoprotein complex GO:0005488//binding "GO:0000398//mRNA splicing, via spliceosome" "gi|148691212|gb|EDL23159.1|/1.41255e-56/gem (nuclear organelle) associated protein 7, isoform CRA_b [Mus musculus]" 216805 3464.68 19.10333333 20.25666667 0.084572396 Up 0.213217872 Flcn folliculin K09594|1|0.0|731|mmu:216805|folliculin GO:0043231//intracellular membrane-bounded organelle;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005911//cell-cell junction;GO:0016020//membrane GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0043409//negative regulation of MAPK cascade;GO:0043009//chordate embryonic development;GO:0016049//cell growth;GO:0009967//positive regulation of signal transduction;GO:0006754//ATP biosynthetic process;GO:0007005//mitochondrion organization;GO:0016477//cell migration;GO:0032845;GO:0034329//cell junction assembly;GO:0016573//histone acetylation;GO:0002328//pro-B cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0010564//regulation of cell cycle process;GO:0007155//cell adhesion;GO:0007266//Rho protein signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0043409//negative regulation of MAPK cascade;GO:0043009//chordate embryonic development;GO:0016049//cell growth;GO:0009967//positive regulation of signal transduction;GO:0006754//ATP biosynthetic process;GO:0007005//mitochondrion organization;GO:0016477//cell migration;GO:0032845;GO:0034329//cell junction assembly;GO:0016573//histone acetylation;GO:0002328//pro-B cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0010564//regulation of cell cycle process;GO:0007155//cell adhesion;GO:0007266//Rho protein signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0043409//negative regulation of MAPK cascade;GO:0043009//chordate embryonic development;GO:0016049//cell growth;GO:0009967//positive regulation of signal transduction;GO:0006754//ATP biosynthetic process;GO:0007005//mitochondrion organization;GO:0016477//cell migration;GO:0032845;GO:0034329//cell junction assembly;GO:0016573//histone acetylation;GO:0002328//pro-B cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0010564//regulation of cell cycle process;GO:0007155//cell adhesion;GO:0007266//Rho protein signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0043409//negative regulation of MAPK cascade;GO:0043009//chordate embryonic development;GO:0016049//cell growth;GO:0009967//positive regulation of signal transduction;GO:0006754//ATP biosynthetic process;GO:0007005//mitochondrion organization;GO:0016477//cell migration;GO:0032845;GO:0034329//cell junction assembly;GO:0016573//histone acetylation;GO:0002328//pro-B cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0010564//regulation of cell cycle process;GO:0007155//cell adhesion;GO:0007266//Rho protein signal transduction gi|22122493|ref|NP_666130.1|/0/folliculin [Mus musculus] 18442 2982.5 21.36666667 22.51666667 0.075631413 Up 0.213217872 P2ry2 "purinergic receptor P2Y, G-protein coupled 2" "K04269|1|0.0|646|mmu:18442|purinergic receptor P2Y, G protein-coupled, 2" GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0044459;GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0044459;GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0044459 GO:0032550;GO:0031685//adenosine receptor binding;GO:0015065//uridine nucleotide receptor activity;GO:0032550;GO:0031685//adenosine receptor binding;GO:0015065//uridine nucleotide receptor activity;GO:0032550;GO:0031685//adenosine receptor binding;GO:0015065//uridine nucleotide receptor activity GO:0035588;GO:0032305//positive regulation of icosanoid secretion;GO:0032496//response to lipopolysaccharide;GO:0009611//response to wounding;GO:0014909//smooth muscle cell migration;GO:0043084//penile erection;GO:0010975//regulation of neuron projection development;GO:0001503//ossification;GO:0042311//vasodilation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0001819//positive regulation of cytokine production;GO:0007600//sensory perception;GO:0070555//response to interleukin-1;GO:0014074//response to purine-containing compound;GO:0035588;GO:0032305//positive regulation of icosanoid secretion;GO:0032496//response to lipopolysaccharide;GO:0009611//response to wounding;GO:0014909//smooth muscle cell migration;GO:0043084//penile erection;GO:0010975//regulation of neuron projection development;GO:0001503//ossification;GO:0042311//vasodilation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0001819//positive regulation of cytokine production;GO:0007600//sensory perception;GO:0070555//response to interleukin-1;GO:0014074//response to purine-containing compound;GO:0035588;GO:0032305//positive regulation of icosanoid secretion;GO:0032496//response to lipopolysaccharide;GO:0009611//response to wounding;GO:0014909//smooth muscle cell migration;GO:0043084//penile erection;GO:0010975//regulation of neuron projection development;GO:0001503//ossification;GO:0042311//vasodilation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0001819//positive regulation of cytokine production;GO:0007600//sensory perception;GO:0070555//response to interleukin-1;GO:0014074//response to purine-containing compound "gi|148684539|gb|EDL16486.1|/0/purinergic receptor P2Y, G-protein coupled 2, isoform CRA_b, partial [Mus musculus]" 52857 2681 20.96666667 22.12 0.077253869 Up 0.213217872 Gramd1a GRAM domain containing 1A K19951|1|2e-09|67.8|pxy:105387021|TBC1 domain family member 9 GO:0031224//intrinsic component of membrane - - "gi|148692001|gb|EDL23948.1|/0/GRAM domain containing 1A, isoform CRA_d [Mus musculus]" 209584 4404 0.933333333 1.14 0.288569498 Up 0.213180263 Tyw3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) K15450|1|7e-72|256|rno:499731|tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282] - GO:0016741;GO:0016741 GO:0006399//tRNA metabolic process;GO:0006399//tRNA metabolic process "gi|148679943|gb|EDL11890.1|/8.21129e-150/tRNA-yW synthesizing protein 3 homolog (S. cerevisiae), isoform CRA_a [Mus musculus]" 56501 5847 3.41 3.063333333 -0.154669378 Down 0.213086239 Elf4 E74-like factor 4 (ets domain transcription factor) K09428|1|0.0|1120|mmu:56501|E74-like factor 1/2/4 GO:0016604//nuclear body GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0030101//natural killer cell activation;GO:0046633//alpha-beta T cell proliferation;GO:0006366//transcription from RNA polymerase II promoter gi|225543336|ref|NP_062654.2|/0/ETS-related transcription factor Elf-4 [Mus musculus] 66874 6284 3.173333333 3.526666667 0.152306149 Up 0.213086239 Ncbp3 nuclear cap binding subunit 3 K06524|1|0.0|832|tup:102476205|integrin alpha E;K12838|2|4e-28|130|acs:100555963|poly(U)-binding-splicing factor PUF60 - - - - 56503 1778 3.06 3.406666667 0.154829138 Up 0.213086239 Ankrd49 ankyrin repeat domain 49 K00166|1|3e-31|139|tsp:Tsp_00515|2-oxoisovalerate dehydrogenase E1 component alpha subunit [EC:1.2.4.4];K10380|2|5e-17|92.0|myd:102754302|ankyrin - - "GO:0006351//transcription, DNA-templated" gi|22165398|ref|NP_062657.2|/4.42348e-119/ankyrin repeat domain-containing protein 49 [Mus musculus] 21951 6444 3.516666667 3.166666667 -0.15124358 Down 0.213086239 Tnks "tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase" K10799|1|0.0|2198|mmu:21951|tankyrase [EC:2.4.2.30] "GO:0000781//chromosome, telomeric region;GO:0005635//nuclear envelope" "GO:0046914//transition metal ion binding;GO:0016763//transferase activity, transferring pentosyl groups" GO:0050658//RNA transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0051100//negative regulation of binding;GO:0034502//protein localization to chromosome;GO:0006468//protein phosphorylation;GO:0045184//establishment of protein localization;GO:0007004//telomere maintenance via telomerase;GO:0000087//mitotic M phase;GO:0030177//positive regulation of Wnt signaling pathway;GO:0006471//protein ADP-ribosylation "gi|148703499|gb|EDL35446.1|/0/tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, isoform CRA_a, partial [Mus musculus]" 19395 2209 12.49666667 11.71 -0.093802249 Down 0.213058032 Rasgrp2 "RAS, guanyl releasing protein 2" K12361|1|0.0|1126|mmu:19395|RAS guanyl-releasing protein 2 GO:0001726//ruffle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0046872//metal ion binding GO:0007264//small GTPase mediated signal transduction gi|131888394|ref|NP_035372.2|/0/RAS guanyl-releasing protein 2 [Mus musculus] 68929 1340.2 12.72666667 13.51666667 0.086884812 Up 0.213058032 Mospd3 motile sperm domain containing 3 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding GO:0044767//single-organism developmental process;GO:0044767//single-organism developmental process gi|28077073|ref|NP_084313.1|/7.66477e-99/motile sperm domain-containing protein 3 [Mus musculus] 75735 7361.24 12.06333333 12.85333333 0.091513944 Up 0.213058032 Pank1 pantothenate kinase 1 K09680|1|0.0|704|bacu:103017263|type II pantothenate kinase [EC:2.7.1.33] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0032550;GO:0016301//kinase activity;GO:0032550;GO:0016301//kinase activity GO:0006575//cellular modified amino acid metabolic process;GO:0009108//coenzyme biosynthetic process;GO:0006766//vitamin metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006575//cellular modified amino acid metabolic process;GO:0009108//coenzyme biosynthetic process;GO:0006766//vitamin metabolic process;GO:0006796//phosphate-containing compound metabolic process gi|167234376|ref|NP_001107811.1|/0/pantothenate kinase 1 isoform 1 [Mus musculus] 21982 1896 12.00333333 12.79666667 0.092332961 Up 0.213058032 Tmem165 transmembrane protein 165 - GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - - gi|535682|gb|AAA40456.1|/8.70736e-129/transmembrane protein precursor [Mus musculus] 12338 3579 0.02 0.11 2.459431619 Up 0.213029824 Capn6 calpain 6 K08575|1|0.0|1330|mmu:12338|calpain-6 [EC:3.4.22.-] GO:0044444//cytoplasmic part;GO:0005819//spindle GO:0015631//tubulin binding;GO:0004197//cysteine-type endopeptidase activity GO:0019538//protein metabolic process;GO:0000226//microtubule cytoskeleton organization gi|157951664|ref|NP_031629.3|/0/calpain-6 [Mus musculus] 16653 4670 4.953333333 5.4 0.124559697 Up 0.212964008 Kras Kirsten rat sarcoma viral oncogene homolog K07827|1|3e-85|320|mmu:16653|GTPase KRas - - - - 23924 1775 5.64 5.19 -0.119960624 Down 0.212964008 Katna1 katanin p60 (ATPase-containing) subunit A1 K07767|1|0.0|951|mmu:23924|katanin p60 ATPase-containing subunit A1 [EC:3.6.4.3] GO:0043005//neuron projection;GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0005819//spindle;GO:0044444//cytoplasmic part "GO:0032550;GO:0046983//protein dimerization activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0015631//tubulin binding;GO:0042623//ATPase activity, coupled" GO:0033036;GO:0000226//microtubule cytoskeleton organization;GO:0010975//regulation of neuron projection development;GO:0032446//protein modification by small protein conjugation;GO:0009154//purine ribonucleotide catabolic process;GO:0000087//mitotic M phase;GO:0016477//cell migration gi|255708413|ref|NP_035965.2|/0/katanin p60 ATPase-containing subunit A1 [Mus musculus] 76265 1972 5.276666667 5.723333333 0.117228784 Up 0.212964008 Tsen54 tRNA splicing endonuclease subunit 54 K15326|1|0.0|924|mmu:76265|tRNA-splicing endonuclease subunit Sen54 - - "GO:0000394//RNA splicing, via endonucleolytic cleavage and ligation" gi|568976237|ref|XP_006534478.1|/0/PREDICTED: tRNA-splicing endonuclease subunit Sen54 isoform X1 [Mus musculus] 71624 1202 0.213333333 0.353333333 0.727920455 Up 0.212935801 4833411C07Rik RIKEN cDNA 4833411C07 gene - - - - "gi|148690104|gb|EDL22051.1|/5.69384e-34/mCG59572, isoform CRA_b [Mus musculus]" 114570 955 0.21 0.346666667 0.723159795 Up 0.212935801 Crip3 cysteine-rich protein 3 K09377|1|2e-28|128|isc:IscW_ISCW017063|cysteine and glycine-rich protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0042110//T cell activation;GO:0042110//T cell activation gi|31982457|ref|NP_858050.1|/1.05109e-127/cysteine-rich protein 3 isoform TLP-A [Mus musculus] 100037278 2482 0.22 0.363333333 0.723790205 Up 0.212935801 Fam129c "family with sequence similarity 129, member C" - - - - gi|568955162|ref|XP_006509593.1|/0/PREDICTED: niban-like protein 2 isoform X1 [Mus musculus] 54141 3822 0.343333333 0.206666667 -0.732304217 Down 0.212935801 Spag5 sperm associated antigen 5 "K17529|1|8e-24|115|mgp:100543796|uncharacterized serine/threonine-protein kinase SgK494 [EC:2.7.11.1];K05291|2|2e-23|114|tgu:100228180|phosphatidylinositol glycan, class S;K16464|3|1e-09|68.6|clv:102087669|centrosomal protein CEP250;K11499|4|2e-09|67.8|ola:101167860|centromere protein F" "GO:0005874//microtubule;GO:0031981//nuclear lumen;GO:0000775//chromosome, centromeric region;GO:0005819//spindle" - GO:0008608//attachment of spindle microtubules to kinetochore;GO:0007067//mitotic nuclear division gi|33859674|ref|NP_059103.1|/0/sperm-associated antigen 5 [Mus musculus] 69090 1502.61 20.66666667 21.81 0.077684055 Up 0.212907593 Ascc1 activating signal cointegrator 1 complex subunit 1 K18666|1|0.0|722|mmu:69090|activating signal cointegrator complex subunit 1 GO:0043234//protein complex;GO:0044424;GO:0043234//protein complex;GO:0044424 GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|568968382|ref|XP_006514102.1|/0/PREDICTED: activating signal cointegrator 1 complex subunit 1 isoform X2 [Mus musculus] 101113 1520 22.27 21.13333333 -0.075581218 Down 0.212907593 Snx21 sorting nexin family member 21 K17932|1|2e-157|558|mmu:101113|sorting nexin-21 - - - - 100732 1925.02 53.34666667 56.09 0.072345455 Up 0.212869984 Mapre3 "microtubule-associated protein, RP/EB family, member 3" "K10436|1|1e-145|519|umr:103671663|microtubule-associated protein, RP/EB family" GO:0005874//microtubule;GO:0044444//cytoplasmic part;GO:0005874//microtubule;GO:0044444//cytoplasmic part GO:0030695//GTPase regulator activity;GO:0015631//tubulin binding;GO:0015631//tubulin binding "GO:0000087//mitotic M phase;GO:0006351//transcription, DNA-templated;GO:0044763;GO:0006351//transcription, DNA-templated" "gi|148705348|gb|EDL37295.1|/3.8254e-146/microtubule-associated protein, RP/EB family, member 3, isoform CRA_b, partial [Mus musculus]" 99738 3013 0.36 0.22 -0.710493383 Down 0.212757155 Kcnc4 "potassium voltage gated channel, Shaw-related subfamily, member 4" K04890|1|0.0|951|mmu:99738|potassium voltage-gated channel Shaw-related subfamily C member 4 GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0033267 GO:0005267//potassium channel activity GO:0007269//neurotransmitter secretion;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|22122333|ref|NP_666034.1|/0/potassium voltage-gated channel subfamily C member 4 [Mus musculus] 434234 2008 0.353333333 0.216666667 -0.705552642 Down 0.212757155 2610020H08Rik RIKEN cDNA 2610020H08 gene K14570|1|0.0|883|rno:309036|RNA exonuclease 1 [EC:3.1.-.-] - - - "gi|148685242|gb|EDL17189.1|/0/RIKEN cDNA 2610020H08, isoform CRA_d, partial [Mus musculus]" 68190 1815 0.896666667 0.706666667 -0.343541908 Down 0.212700741 Dubr Dppa2 upstream binding RNA - - - - gi|26342773|dbj|BAC35043.1|/2.70662e-71/unnamed protein product [Mus musculus] 218397 5101 2.836666667 2.526666667 -0.166961284 Down 0.212663131 Rasa1 RAS p21 protein activator 1 K04352|1|0.0|1743|mmu:218397|Ras GTPase-activating protein 1 GO:0016020//membrane;GO:0031252//cell leading edge GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0019899//enzyme binding GO:0001952//regulation of cell-matrix adhesion;GO:0007275//multicellular organism development;GO:0043066//negative regulation of apoptotic process;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0008064//regulation of actin polymerization or depolymerization;GO:0048646//anatomical structure formation involved in morphogenesis gi|164663773|ref|NP_663427.2|/0/ras GTPase-activating protein 1 [Mus musculus] 77733 4049 2.833333333 2.526666667 -0.165264993 Down 0.212663131 Rnf170 ring finger protein 170 K15707|1|5e-137|491|mmu:77733|RING finger protein 170 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0003824//catalytic activity - gi|148692281|gb|EDL24228.1|/4.71551e-136/mCG1050561 [Mus musculus] 235380 10614 2.803333333 2.493333333 -0.16906753 Down 0.212663131 Dmxl2 Dmx-like 2 K16482|1|5e-09|68.2|tgu:101234082|centriolar protein POC1;K12662|5|3e-08|65.9|cbr:CBG12355|U4/U6 small nuclear ribonucleoprotein PRP4 - - - gi|189491684|ref|NP_766359.2|/0/dmX-like protein 2 [Mus musculus] 26390 6954 2.723333333 2.413333333 -0.174346381 Down 0.212663131 Mapkbp1 mitogen-activated protein kinase binding protein 1 K17917|1|2e-49|201|pxy:105395501|sorting nexin-1/2;K16342|2|3e-34|151|oaa:100089728|cytosolic phospholipase A2 [EC:3.1.1.4];K18598|3|3e-26|124|hmg:100207255|echinoderm microtubule-associated protein-like 6 - - GO:0000186//activation of MAPKK activity gi|213385289|ref|NP_036071.3|/0/mitogen-activated protein kinase-binding protein 1 [Mus musculus] 668030 2592 0.07 0.183333333 1.389042291 Up 0.212653729 Gm14432 predicted gene 14432 K09228|1|0.0|1083|mmu:100043915|KRAB domain-containing zinc finger protein - - - "gi|123858410|emb|CAM27978.1|/0/novel KRAB box and zinc finger, C2H2 type domain containing protein [Mus musculus]" 109778 1394 8.75 9.353333333 0.096197586 Up 0.212634924 Blvra biliverdin reductase A K00214|1|1e-138|495|mmu:109778|biliverdin reductase [EC:1.3.1.24] GO:0044424 "GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor" GO:0044710;GO:0006787 gi|568915051|ref|XP_006498632.1|/7.01458e-159/PREDICTED: biliverdin reductase A isoform X2 [Mus musculus] 21423 3313.41 8.646666667 8.046666667 -0.103752803 Down 0.212634924 Tcf3 transcription factor 3 K09063|1|0.0|914|mmu:21423|transcription factor E2-alpha GO:0043231//intracellular membrane-bounded organelle;GO:0000786//nucleosome;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000786//nucleosome;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000786//nucleosome;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000786//nucleosome;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000786//nucleosome;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000786//nucleosome;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000786//nucleosome;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000786//nucleosome;GO:0043234//protein complex GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0008134//transcription factor binding GO:0030217//T cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0030183//B cell differentiation;GO:0048537//mucosal-associated lymphoid tissue development;GO:0030888//regulation of B cell proliferation;GO:0051318;GO:0051726//regulation of cell cycle;GO:0044093;GO:0002237//response to molecule of bacterial origin;GO:0016573//histone acetylation;GO:0030182//neuron differentiation;GO:0030217//T cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0030183//B cell differentiation;GO:0048537//mucosal-associated lymphoid tissue development;GO:0030888//regulation of B cell proliferation;GO:0051318;GO:0051726//regulation of cell cycle;GO:0044093;GO:0002237//response to molecule of bacterial origin;GO:0016573//histone acetylation;GO:0030182//neuron differentiation;GO:0030217//T cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0030183//B cell differentiation;GO:0048537//mucosal-associated lymphoid tissue development;GO:0030888//regulation of B cell proliferation;GO:0051318;GO:0051726//regulation of cell cycle;GO:0044093;GO:0002237//response to molecule of bacterial origin;GO:0016573//histone acetylation;GO:0030182//neuron differentiation;GO:0030217//T cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0030183//B cell differentiation;GO:0048537//mucosal-associated lymphoid tissue development;GO:0030888//regulation of B cell proliferation;GO:0051318;GO:0051726//regulation of cell cycle;GO:0044093;GO:0002237//response to molecule of bacterial origin;GO:0016573//histone acetylation;GO:0030182//neuron differentiation;GO:0030217//T cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0030183//B cell differentiation;GO:0048537//mucosal-associated lymphoid tissue development;GO:0030888//regulation of B cell proliferation;GO:0051318;GO:0051726//regulation of cell cycle;GO:0044093;GO:0002237//response to molecule of bacterial origin;GO:0016573//histone acetylation;GO:0030182//neuron differentiation;GO:0030217//T cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0030183//B cell differentiation;GO:0048537//mucosal-associated lymphoid tissue development;GO:0030888//regulation of B cell proliferation;GO:0051318;GO:0051726//regulation of cell cycle;GO:0044093;GO:0002237//response to molecule of bacterial origin;GO:0016573//histone acetylation;GO:0030182//neuron differentiation;GO:0030217//T cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0030183//B cell differentiation;GO:0048537//mucosal-associated lymphoid tissue development;GO:0030888//regulation of B cell proliferation;GO:0051318;GO:0051726//regulation of cell cycle;GO:0044093;GO:0002237//response to molecule of bacterial origin;GO:0016573//histone acetylation;GO:0030182//neuron differentiation;GO:0030217//T cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0030183//B cell differentiation;GO:0048537//mucosal-associated lymphoid tissue development;GO:0030888//regulation of B cell proliferation;GO:0051318;GO:0051726//regulation of cell cycle;GO:0044093;GO:0002237//response to molecule of bacterial origin;GO:0016573//histone acetylation;GO:0030182//neuron differentiation "gi|148699595|gb|EDL31542.1|/0/transcription factor E2a, isoform CRA_b, partial [Mus musculus]" 110052 2606 7.95 8.546666667 0.104406996 Up 0.212634924 Dek DEK oncogene (DNA binding) K17046|1|3e-81|306|mmu:110052|protein DEK GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0005515//protein binding GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006325//chromatin organization;GO:0006282//regulation of DNA repair gi|253795498|ref|NP_080176.2|/2.22811e-80/protein DEK [Mus musculus] 55946 4424 8.646666667 9.246666667 0.096789308 Up 0.212634924 Ap3m1 "adaptor-related protein complex 3, mu 1 subunit" K12398|1|0.0|858|cjc:100406271|AP-3 complex subunit mu GO:0043231//intracellular membrane-bounded organelle;GO:0030119//AP-type membrane coat adaptor complex - GO:0048489//synaptic vesicle transport;GO:0008088//axo-dendritic transport;GO:0015031//protein transport gi|634847500|ref|XP_007938785.1|/0/PREDICTED: AP-3 complex subunit mu-1 isoform X1 [Orycteropus afer afer] 72106 2108 50.83 53.50333333 0.073948545 Up 0.212634924 Jmjd8 jumonji domain containing 8 K20408|1|4e-109|398|cjc:100402756|WD repeat-containing protein 24;K03283|4|2e-59|233|tru:101079118|heat shock 70kDa protein 1/8;K09561|5|2e-44|113|ptr:453803|STIP1 homology and U-box containing protein 1 [EC:2.3.2.27] - - - "gi|148690512|gb|EDL22459.1|/4.30329e-156/RIKEN cDNA 2610003J06, isoform CRA_c [Mus musculus]" 54614 3182 8.246666667 8.843333333 0.100779175 Up 0.212634924 Prpf40b pre-mRNA processing factor 40B K12821|1|0.0|936|mmu:54614|pre-mRNA-processing factor 40 - - - - 72454 3108 8.83 8.226666667 -0.102105449 Down 0.212634924 Ccdc71 coiled-coil domain containing 71 "K06243|1|8e-51|205|tgu:100222711|laminin, beta 2" - - - gi|568963177|ref|XP_006511899.1|/0/PREDICTED: coiled-coil domain-containing protein 71 isoform X2 [Mus musculus] 78558 2718.09 52.57666667 49.91333333 -0.074997425 Down 0.212625522 Htra3 HtrA serine peptidase 3 K08785|1|0.0|857|mmu:78558|HtrA serine peptidase 3 [EC:3.4.21.-] - GO:0004175//endopeptidase activity;GO:0019838//growth factor binding;GO:0004175//endopeptidase activity;GO:0019838//growth factor binding GO:0030509//BMP signaling pathway;GO:0019538//protein metabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0030509//BMP signaling pathway;GO:0019538//protein metabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway gi|110815869|ref|NP_084403.2|/0/serine protease HTRA3 isoform a precursor [Mus musculus] 216292 2039 1.916666667 1.66 -0.207416214 Down 0.212428072 Mettl25 methyltransferase like 25 - - GO:0016741 GO:0008152//metabolic process gi|283135209|ref|NP_997405.2|/0/methyltransferase-like protein 25 [Mus musculus] 329739 5702 3.113333333 2.78 -0.163375166 Down 0.212428072 Fam102b "family with sequence similarity 102, member B" K11339|1|1e-09|69.7|cjc:100414416|mortality factor 4-like protein 1 - - - gi|254675227|ref|NP_001157039.1|/0/protein FAM102B [Mus musculus] 26572 1583 51.36333333 53.97666667 0.071597054 Up 0.212428072 Cops3 COP9 signalosome subunit 3 K12177|1|0.0|834|mmu:26572|COP9 signalosome complex subunit 3 - - - - 72691 2049 2.76 3.09 0.162938571 Up 0.212428072 Calhm2 calcium homeostasis modulator 2 K19739|1|0.0|654|mmu:72691|calcium homeostasis modulator protein 2 GO:0031224//intrinsic component of membrane - - "gi|148710082|gb|EDL42028.1|/0/RIKEN cDNA 2810048G17, isoform CRA_a, partial [Mus musculus]" 67096 1950 52.06333333 54.66 0.070217777 Up 0.212428072 Mmachc "methylmalonic aciduria cblC type, with homocystinuria" K14618|1|8e-149|530|mmu:67096|methylmalonic aciduria homocystinuria type C protein GO:0043231//intracellular membrane-bounded organelle GO:0019842//vitamin binding GO:0009235//cobalamin metabolic process gi|156105691|ref|NP_080238.2|/6.65221e-148/methylmalonic aciduria and homocystinuria type C protein homolog [Mus musculus] 268759 2001.01 0.373333333 0.23 -0.698830465 Down 0.212390462 9930012K11Rik RIKEN cDNA 9930012K11 gene - - - - "gi|21618991|gb|AAH32212.1|/0/9930012K11Rik protein, partial [Mus musculus]" 333329 6201 0.373333333 0.23 -0.698830465 Down 0.212390462 Cngb1 cyclic nucleotide gated channel beta 1 K04952|1|0.0|1249|mmu:333329|cyclic nucleotide gated channel beta 1 GO:0033267;GO:0034703//cation channel complex;GO:0033267;GO:0034703//cation channel complex GO:0005221//intracellular cyclic nucleotide activated cation channel activity;GO:0005221//intracellular cyclic nucleotide activated cation channel activity GO:0007606//sensory perception of chemical stimulus;GO:0006811//ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0007601//visual perception;GO:0051262//protein tetramerization;GO:0034613//cellular protein localization;GO:0007165//signal transduction;GO:0007606//sensory perception of chemical stimulus;GO:0006811//ion transport;GO:0006874//cellular calcium ion homeostasis;GO:0007601//visual perception;GO:0051262//protein tetramerization;GO:0034613//cellular protein localization;GO:0007165//signal transduction "gi|148679214|gb|EDL11161.1|/1.85217e-115/cDNA sequence BC016201, isoform CRA_a [Mus musculus]" 75974 6665 0.373333333 0.23 -0.698830465 Down 0.212390462 Dock11 dedicator of cytokinesis 11 K13708|1|1e-18|99.4|mde:101891400|dedicator of cytokinesis protein 1;K05727|2|1e-17|96.3|phi:102101829|dedicator of cytokinesis protein 3 GO:0044444//cytoplasmic part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0017016//Ras GTPase binding;GO:0008289//lipid binding GO:0019222//regulation of metabolic process;GO:0007599//hemostasis;GO:0035556//intracellular signal transduction gi|125660464|ref|NP_001009947.2|/0/dedicator of cytokinesis protein 11 [Mus musculus] 74589 2042 6.693333333 7.206666667 0.106607254 Up 0.21234345 Kbtbd12 kelch repeat and BTB (POZ) domain containing 12 K10457|1|3e-65|252|sko:100372185|kelch-like protein 20;K10443|2|3e-59|232|sko:100372040|kelch-like protein 2/3 - - - gi|522022357|ref|NP_001265600.1|/0/kelch repeat and BTB domain-containing protein 12 [Mus musculus] 228961 2110 54.16 56.75 0.067392653 Up 0.21234345 Npepl1 aminopeptidase-like 1 K09611|1|0.0|995|mmu:228961|probable aminopeptidase NPEPL1 [EC:3.4.11.-] GO:0044424 GO:0046914//transition metal ion binding;GO:0008237//metallopeptidase activity;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process "gi|148674714|gb|EDL06661.1|/0/aminopeptidase-like 1, isoform CRA_a, partial [Mus musculus]" 66695 2362 6.846666667 6.336666667 -0.11167765 Down 0.21234345 Aspn asporin K08120|1|0.0|727|mmu:66695|asporin GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix GO:0005488//binding;GO:0022829//wide pore channel activity;GO:0005488//binding;GO:0022829//wide pore channel activity GO:0001503//ossification;GO:0034505//tooth mineralization;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001503//ossification;GO:0034505//tooth mineralization;GO:0007179//transforming growth factor beta receptor signaling pathway gi|27754118|ref|NP_079987.2|/0/asporin preproprotein [Mus musculus] 71368 795 7.243333333 6.73 -0.106047264 Down 0.21234345 5430431A17Rik RIKEN cDNA 5430431A17 gene - - - - - 78339 4676 6.92 6.406666667 -0.111198108 Down 0.21234345 Ttyh3 tweety family member 3 K02923|1|5e-75|286|cmy:102946987|large subunit ribosomal protein L38e GO:0034702//ion channel complex;GO:0034702//ion channel complex GO:0005253//anion channel activity;GO:0005253//anion channel activity GO:0015698//inorganic anion transport;GO:0015698//inorganic anion transport gi|254588052|ref|NP_780483.2|/0/protein tweety homolog 3 isoform 2 [Mus musculus] 26373 4070 12.05 12.82333333 0.089738182 Up 0.212296438 Clcn7 "chloride channel, voltage-sensitive 7" K05016|1|0.0|1448|mmu:26373|chloride channel 7 - - - - 231326 3694 2.12 1.846666667 -0.199140789 Down 0.212164805 Aasdh aminoadipate-semialdehyde dehydrogenase K00142|1|0.0|2209|mmu:231326|acyl-CoA synthetase [EC:6.2.1.-] - "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0032550" GO:0032787//monocarboxylic acid metabolic process;GO:0044238//primary metabolic process "gi|148705966|gb|EDL37913.1|/0/RIKEN cDNA A230062G08, isoform CRA_a, partial [Mus musculus]" 240055 6195 2.05 1.783333333 -0.201047519 Down 0.212164805 Neurl1b neuralized E3 ubiquitin protein ligase 1B K01931|1|0.0|975|mmu:240055|protein neuralized [EC:2.3.2.27] GO:0044424 GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0007166//cell surface receptor signaling pathway;GO:0032446//protein modification by small protein conjugation gi|126116567|ref|NP_001075125.1|/0/E3 ubiquitin-protein ligase NEURL1B [Mus musculus] 106795 1616 2.046666667 1.78 -0.201398914 Down 0.212164805 Tcf19 transcription factor 19 - - - - "gi|148691270|gb|EDL23217.1|/1.17207e-150/transcription factor 19, isoform CRA_b, partial [Mus musculus]" 19298 3131 52.89333333 55.39666667 0.066713272 Up 0.212014367 Pex19 peroxisomal biogenesis factor 19 K13337|1|2e-138|496|mmu:19298|peroxin-19 GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0005903//brush border;GO:0044439;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0005903//brush border;GO:0044439 GO:0033328//peroxisome membrane targeting sequence binding;GO:0019899//enzyme binding;GO:0033328//peroxisome membrane targeting sequence binding;GO:0019899//enzyme binding GO:0051100//negative regulation of binding;GO:0006457//protein folding;GO:0006625//protein targeting to peroxisome;GO:0031647//regulation of protein stability;GO:0051100//negative regulation of binding;GO:0006457//protein folding;GO:0006625//protein targeting to peroxisome;GO:0031647//regulation of protein stability gi|226958492|ref|NP_001152997.1|/6.96183e-83/peroxisomal biogenesis factor 19 isoform b [Mus musculus] 18185 2377 3.56 3.926666667 0.141427892 Up 0.21198616 Nrl neural retina leucine zipper gene K09038|1|2e-100|369|mmu:18185|neural retina-specific leucine zipper protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0030275//LRR domain binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030275//LRR domain binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030275//LRR domain binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030275//LRR domain binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0007468//regulation of rhodopsin gene expression;GO:0042462//eye photoreceptor cell development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007468//regulation of rhodopsin gene expression;GO:0042462//eye photoreceptor cell development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007468//regulation of rhodopsin gene expression;GO:0042462//eye photoreceptor cell development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007468//regulation of rhodopsin gene expression;GO:0042462//eye photoreceptor cell development;GO:0006366//transcription from RNA polymerase II promoter gi|6679132|ref|NP_032762.1|/1.46472e-99/neural retina-specific leucine zipper protein [Mus musculus] 98221 1230 52.24333333 54.73333333 0.067172772 Up 0.21198616 Eif3m "eukaryotic translation initiation factor 3, subunit M" K15030|1|0.0|706|mmu:98221|translation initiation factor 3 subunit M - - - - 78287 5242 3.97 3.6 -0.141142101 Down 0.21198616 Rbsn "rabenosyn, RAB effector" K12481|1|0.0|1402|mmu:78287|rabenosyn-5 GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0046914//transition metal ion binding;GO:0017016//Ras GTPase binding GO:0045184//establishment of protein localization gi|31541996|ref|NP_084357.2|/0/rabenosyn-5 [Mus musculus] 71583 2159 0.16 0.29 0.857980995 Up 0.211910941 9130008F23Rik RIKEN cDNA 9130008F23 gene - - - - gi|58037251|ref|NP_082110.1|/6.92395e-101/uncharacterized protein C6orf141 homolog [Mus musculus] 100504663 3466 4.536666667 4.136666667 -0.133163951 Down 0.211910941 Atg14 autophagy related 14 K17889|1|0.0|920|mmu:100504663|beclin 1-associated autophagy-related key regulator GO:0005773//vacuole;GO:0000407//pre-autophagosomal structure - GO:0007033//vacuole organization;GO:0006914//autophagy gi|27369860|ref|NP_766187.1|/0/beclin 1-associated autophagy-related key regulator [Mus musculus] 18181 3444.6 4.33 4.733333333 0.128489499 Up 0.211910941 Nrf1 nuclear respiratory factor 1 K11831|1|0.0|647|mgp:100542974|nuclear respiratory factor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001071//nucleic acid binding transcription factor activity "GO:0033993//response to lipid;GO:0006996//organelle organization;GO:0009719;GO:0009628//response to abiotic stimulus;GO:0014070//response to organic cyclic compound;GO:0006366//transcription from RNA polymerase II promoter;GO:0006996//organelle organization;GO:0043627//response to estrogen;GO:0009628//response to abiotic stimulus;GO:0009887//organ morphogenesis;GO:0002237//response to molecule of bacterial origin;GO:0006351//transcription, DNA-templated;GO:0006996//organelle organization;GO:0043627//response to estrogen;GO:0009628//response to abiotic stimulus;GO:0009887//organ morphogenesis;GO:0002237//response to molecule of bacterial origin;GO:0006351//transcription, DNA-templated;GO:0033993//response to lipid;GO:0006996//organelle organization;GO:0009719;GO:0009628//response to abiotic stimulus;GO:0014070//response to organic cyclic compound;GO:0006366//transcription from RNA polymerase II promoter" gi|918630873|ref|XP_013358732.1|/0/PREDICTED: nuclear respiratory factor 1 isoform X3 [Chinchilla lanigera] 16571 4712 0.296666667 0.163333333 -0.861023587 Down 0.211910941 Kif4 kinesin family member 4 K10395|1|0.0|2206|mmu:16571|kinesin family member 4/21/27 GO:0034399//nuclear periphery;GO:0044444//cytoplasmic part;GO:0005819//spindle GO:0032550;GO:0003676//nucleic acid binding;GO:0003774//motor activity GO:0002478;GO:0006935//chemotaxis;GO:0008088//axo-dendritic transport;GO:0007599//hemostasis;GO:0016043//cellular component organization gi|162287089|ref|NP_032472.2|/0/chromosome-associated kinesin KIF4 [Mus musculus] 432508 6534 4.193333333 4.593333333 0.131443966 Up 0.211910941 Cpsf6 cleavage and polyadenylation specific factor 6 K14398|1|5e-101|373|chx:102186747|cleavage and polyadenylation specificity factor subunit 6/7 GO:0043234//protein complex;GO:0016604//nuclear body GO:0003723//RNA binding GO:0031124//mRNA 3'-end processing;GO:0051259//protein oligomerization gi|926691741|ref|XP_013819342.1|/4.11172e-100/PREDICTED: cleavage and polyadenylation specificity factor subunit 6 isoform X4 [Capra hircus] 63985 4171 4.733333333 4.333333333 -0.127379306 Down 0.211910941 Gmfb "glia maturation factor, beta" K20368|1|7e-50|202|aam:106494587|protein cornichon GO:0044464 GO:0008092//cytoskeletal protein binding;GO:0060089;GO:0005102//receptor binding;GO:0019887//protein kinase regulator activity GO:0048731//system development;GO:0001933//negative regulation of protein phosphorylation;GO:0044093;GO:0007154//cell communication "gi|148688775|gb|EDL20722.1|/3.0005e-85/glia maturation factor, beta, isoform CRA_a, partial [Mus musculus]" 233905 6327 4.59 4.186666667 -0.132692095 Down 0.211910941 Zfp646 zinc finger protein 646 K09228|1|4e-85|320|shr:100916702|KRAB domain-containing zinc finger protein - - - gi|46358380|ref|NP_766337.2|/0/zinc finger protein 646 [Mus musculus] 68153 1553.72 4.296666667 4.696666667 0.128419348 Up 0.211910941 Gtf2e2 "general transcription factor II E, polypeptide 2 (beta subunit)" K03137|1|3e-143|511|mmu:68153|transcription initiation factor TFIIE subunit beta GO:0005667//transcription factor complex;GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter gi|568954230|ref|XP_006509248.1|/3.09157e-143/PREDICTED: general transcription factor IIE subunit 2 isoform X2 [Mus musculus] 106205 3857 4.6 4.2 -0.131244533 Down 0.211910941 Zc3h7a zinc finger CCCH type containing 7 A K05864|1|1e-09|68.6|tru:101066949|peptidyl-prolyl isomerase D [EC:5.2.1.8];K09574|2|2e-09|68.2|sko:100378510|FK506-binding protein 8 [EC:5.2.1.8];K19870|3|2e-09|68.2|mdo:100030544|sperm-associated antigen 1 - - - gi|74181424|dbj|BAE29985.1|/0/unnamed protein product [Mus musculus] 16882 5984 4.566666667 4.163333333 -0.133402416 Down 0.211910941 Lig3 "ligase III, DNA, ATP-dependent" K10776|1|0.0|1907|mmu:16882|DNA ligase 3 [EC:6.5.1.1] GO:0000794//condensed nuclear chromosome;GO:0000794//condensed nuclear chromosome;GO:0000794//condensed nuclear chromosome;GO:0000794//condensed nuclear chromosome GO:0032550;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0016886;GO:0032550;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0016886;GO:0032550;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0016886;GO:0032550;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0016886 GO:0006266//DNA ligation;GO:0000018//regulation of DNA recombination;GO:0000726;GO:0006266//DNA ligation;GO:0000018//regulation of DNA recombination;GO:0000726;GO:0006266//DNA ligation;GO:0000018//regulation of DNA recombination;GO:0000726;GO:0006266//DNA ligation;GO:0000018//regulation of DNA recombination;GO:0000726 gi|568971910|ref|XP_006532410.1|/0/PREDICTED: DNA ligase 3 isoform X2 [Mus musculus] 66146 3842 11.96 11.2 -0.094718657 Down 0.211816917 Tmem57 transmembrane protein 57 K12478|1|4e-09|67.0|cfr:102518430|early endosome antigen 1 GO:0043005//neuron projection;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane - GO:0007417//central nervous system development "gi|119628283|gb|EAX07878.1|/0/transmembrane protein 57, isoform CRA_c [Homo sapiens]" 22418 4354 1.97 2.246666667 0.189590461 Up 0.211798112 Wnt5a "wingless-type MMTV integration site family, member 5A" "K00444|1|0.0|797|rno:64566|wingless-type MMTV integration site family, member 5" - - - gi|564388004|ref|XP_006252726.1|/0/PREDICTED: protein Wnt-5a isoform X1 [Rattus norvegicus] 59288 1532 19.04666667 20.14666667 0.081002624 Up 0.211798112 Dctn5 dynactin 5 K10427|1|7e-95|344|umr:103668855|dynactin 5 GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0044444//cytoplasmic part GO:0003824//catalytic activity GO:0002478 gi|671009048|ref|XP_008695380.1|/6.00423e-94/PREDICTED: dynactin subunit 5 [Ursus maritimus] 228778 1718.92 2.22 1.94 -0.194503024 Down 0.211798112 6820408C15Rik RIKEN cDNA 6820408C15 gene K07847|1|9e-10|53.9|mgp:100542192|Rad and Gem related GTP binding protein 1 - - - gi|29244072|ref|NP_808324.1|/0/uncharacterized protein C20orf96 homolog isoform 2 [Mus musculus] 228019 2027.36 1.96 2.243333333 0.19479035 Up 0.211798112 Mettl8 methyltransferase like 8 K00599|1|2e-52|209|aga:AgaP_AGAP009818|methyltransferase-like protein 6 [EC:2.1.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016741;GO:0016741 GO:0030154//cell differentiation;GO:0014706//striated muscle tissue development;GO:0016570//histone modification;GO:0030154//cell differentiation;GO:0014706//striated muscle tissue development;GO:0016570//histone modification gi|161377429|ref|NP_663499.2|/0/methyltransferase-like protein 8 isoform a [Mus musculus] 67266 2724 2.033333333 2.313333333 0.18612642 Up 0.211798112 Fam69a "family with sequence similarity 69, member A" K20242|1|3e-56|223|clv:102095124|ecotropic viral integration site 5 protein GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|21313032|ref|NP_080338.1|/0/protein FAM69A [Mus musculus] 215051 2208 4.96 5.4 0.122619287 Up 0.211722893 Bud13 BUD13 homolog K13106|1|0.0|1075|mmu:215051|pre-mRNA-splicing factor CWC26 - - - - 272589 4967 5.406666667 4.963333333 -0.123430066 Down 0.211722893 Tbcel tubulin folding cofactor E-like K18273|1|0.0|781|pps:100980308|alpha-tectorin GO:0043232 - - "gi|148693595|gb|EDL25542.1|/0/leucine rich repeat containing 35, isoform CRA_b, partial [Mus musculus]" 72149 2453.97 4.92 5.363333333 0.124471605 Up 0.211722893 Strada STE20-related kinase adaptor alpha K08271|1|0.0|757|mmu:72149|STE20-related kinase adapter protein alpha GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004672//protein kinase activity;GO:0019887//protein kinase regulator activity;GO:0019899//enzyme binding;GO:0032550;GO:0004672//protein kinase activity;GO:0019899//enzyme binding;GO:0019887//protein kinase regulator activity;GO:0032550;GO:0004672//protein kinase activity;GO:0019899//enzyme binding;GO:0019887//protein kinase regulator activity GO:0006886//intracellular protein transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0051259//protein oligomerization;GO:0022402//cell cycle process;GO:0045860//positive regulation of protein kinase activity;GO:0019217//regulation of fatty acid metabolic process;GO:0051259//protein oligomerization;GO:0006886//intracellular protein transport;GO:0045860//positive regulation of protein kinase activity;GO:0051259//protein oligomerization;GO:0006886//intracellular protein transport;GO:0045860//positive regulation of protein kinase activity gi|356995842|ref|NP_001239378.1|/0/STE20-related kinase adapter protein alpha isoform 3 [Mus musculus] 14009 3950.83 1.21 1 -0.275007047 Down 0.211666479 Etv1 ets variant 1 K09431|1|0.0|984|mmu:14009|ets translocation variant 1 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006935//chemotaxis;GO:0048513//animal organ development;GO:0048666//neuron development;GO:0006351//transcription, DNA-templated;GO:0009612//response to mechanical stimulus" gi|6679701|ref|NP_031986.1|/0/ETS translocation variant 1 isoform a [Mus musculus] 73991 2818 0.956666667 1.163333333 0.2821763 Up 0.211666479 Atl1 atlastin GTPase 1 K17339|1|0.0|1061|mmu:73991|atlastin [EC:3.6.5.-] GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0012505//endomembrane system;GO:0031985//Golgi cisterna GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity GO:0006996//organelle organization;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0051259//protein oligomerization;GO:0009154//purine ribonucleotide catabolic process "gi|148704645|gb|EDL36592.1|/0/spastic paraplegia 3A homolog (human), isoform CRA_b, partial [Mus musculus]" 327946 3189 0.973333333 1.18 0.277780991 Up 0.211666479 Gm12295 predicted gene 12295 - - - - "gi|148678458|gb|EDL10405.1|/1.44613e-68/mCG146118, partial [Mus musculus]" 13731 3440 19.55333333 18.46 -0.083012017 Down 0.211619467 Emp2 epithelial membrane protein 2 K19289|1|8e-23|112|ola:101157512|peripheral myelin protein 22 GO:0044459;GO:0031224//intrinsic component of membrane GO:0005102//receptor binding GO:0007229//integrin-mediated signaling pathway gi|111154059|ref|NP_031955.2|/1.08738e-77/epithelial membrane protein 2 [Mus musculus] 56711 4635 0.19 0.076666667 -1.309328058 Down 0.211506638 Plag1 pleiomorphic adenoma gene 1 K19484|1|0.0|915|mmu:56711|zinc finger protein PLAG1 - - - gi|227330577|ref|NP_064353.2|/0/zinc finger protein PLAG1 [Mus musculus] 72729 3138 11.44333333 12.19333333 0.091585218 Up 0.211440821 Cdc42se2 CDC42 small effector 2 - GO:0031981//nuclear lumen;GO:0044459;GO:0043232 GO:0005488//binding GO:0022604//regulation of cell morphogenesis;GO:0006897//endocytosis;GO:0007165//signal transduction "gi|148701578|gb|EDL33525.1|/8.36751e-53/mCG1437, isoform CRA_a [Mus musculus]" 78935 4699 0.916666667 0.73 -0.328500749 Down 0.211431419 Saal1 serum amyloid A-like 1 K00502|1|1e-149|533|cjo:107314681|tryptophan 5-monooxygenase [EC:1.14.16.4] - - GO:0002526//acute inflammatory response gi|198278397|ref|NP_084509.1|/0/protein SAAL1 [Mus musculus] 13051 3753 1.49 1.263333333 -0.238076983 Down 0.211422017 Cx3cr1 chemokine (C-X3-C motif) receptor 1 K04192|1|3e-171|605|mmu:13051|CX3C chemokine receptor 1 GO:0031224//intrinsic component of membrane;GO:0043025//neuronal cell body;GO:0042995//cell projection;GO:0044444//cytoplasmic part GO:0004950//chemokine receptor activity GO:0001525//angiogenesis;GO:0071363//cellular response to growth factor stimulus;GO:0032496//response to lipopolysaccharide;GO:0001774//microglial cell activation;GO:0006915//apoptotic process;GO:0019221//cytokine-mediated signaling pathway;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0022610;GO:0021987//cerebral cortex development;GO:0030595//leukocyte chemotaxis gi|87299632|ref|NP_034117.3|/2.69361e-170/CX3C chemokine receptor 1 [Mus musculus] 18109 2596 1.5 1.27 -0.240134004 Down 0.211422017 Mycn "v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived" K09109|1|7e-169|597|mmu:18109|N-myc proto-oncogene protein GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0006366//transcription from RNA polymerase II promoter;GO:0048562//embryonic organ morphogenesis;GO:0045686//negative regulation of glial cell differentiation;GO:0030326//embryonic limb morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0030323//respiratory tube development;GO:0060562//epithelial tube morphogenesis;GO:0008219//cell death;GO:0072593//reactive oxygen species metabolic process "gi|148666033|gb|EDK98449.1|/0/v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian), isoform CRA_a, partial [Mus musculus]" 12544 1960.98 1.226666667 1.453333333 0.244622369 Up 0.211422017 Cdc45 cell division cycle 45 K06628|1|0.0|1019|mmu:12544|cell division control protein 45 GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center - GO:0006259//DNA metabolic process;GO:0044763;GO:0006259//DNA metabolic process;GO:0044763 gi|239052106|ref|NP_001155095.1|/0/cell division control protein 45 homolog isoform 2 [Mus musculus] 67053 2467 6.526666667 7.023333333 0.105809549 Up 0.211309188 Rpp14 ribonuclease P 14 subunit K14529|1|2e-60|236|ptr:747483|ribonuclease P protein subunit RPP14 [EC:3.1.26.5] GO:0043231//intracellular membrane-bounded organelle GO:0004518//nuclease activity GO:0006399//tRNA metabolic process;GO:0044710 gi|148688634|gb|EDL20581.1|/1.26314e-77/ribonuclease P 14 subunit (human) [Mus musculus] 94232 3372 51.57 49.23333333 -0.066896625 Down 0.211205762 Ubqln4 ubiquilin 4 K04523|1|0.0|810|mmu:94232|ubiquilin GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane GO:0043130//ubiquitin binding GO:0061136//regulation of proteasomal protein catabolic process gi|15805016|ref|NP_277068.1|/0/ubiquilin-4 [Mus musculus] 69770 651 3.57 3.226666667 -0.145879527 Down 0.211055324 1600002K03Rik RIKEN cDNA 1600002K03 gene - GO:0044424;GO:0031224//intrinsic component of membrane - - gi|58037177|ref|NP_081483.1|/3.64557e-51/uncharacterized membrane protein C19orf24 homolog precursor [Mus musculus] 230393 5796 3.51 3.173333333 -0.145471958 Down 0.211055324 Focad focadhesin - GO:0005924//cell-substrate adherens junction;GO:0031224//intrinsic component of membrane - - gi|124487123|ref|NP_001074653.1|/0/focadhesin [Mus musculus] 18408 3469 3.406666667 3.063333333 -0.15325843 Down 0.211055324 Slc25a15 "solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15" K15101|1|1e-163|580|mmu:18408|solute carrier family 25 (mitochondrial ornithine transporter) member 2/15 GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane GO:0008324//cation transmembrane transporter activity GO:0019752//carboxylic acid metabolic process;GO:0006839//mitochondrial transport;GO:0019627//urea metabolic process gi|880971033|ref|XP_012981844.1|/1.94928e-167/PREDICTED: mitochondrial ornithine transporter 1 isoform X1 [Mesocricetus auratus] 66602 1503.32 18.05 19.10666667 0.082077272 Up 0.210914288 1700020I14Rik RIKEN cDNA 1700020I14 gene - - - - - 67469 3148 20.34 19.27666667 -0.077464078 Down 0.210914288 Abhd5 abhydrolase domain containing 5 K13699|1|0.0|681|mmu:67469|abhydrolase domain-containing protein 5 [EC:2.3.1.51] GO:0044444//cytoplasmic part GO:0005488//binding;GO:0016298//lipase activity;GO:0016411//acylglycerol O-acyltransferase activity GO:0048869//cellular developmental process;GO:0010896//regulation of triglyceride catabolic process;GO:0051004;GO:0032787//monocarboxylic acid metabolic process;GO:0010888//negative regulation of lipid storage;GO:0019538//protein metabolic process;GO:0046473//phosphatidic acid metabolic process gi|117558822|gb|AAI27471.1|/0/Abhd5 protein [Rattus norvegicus] 12041 2857 48.59 46.29 -0.06995887 Down 0.210895483 Bckdk branched chain ketoacid dehydrogenase kinase K00905|1|0.0|739|mmu:12041|[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase [EC:2.7.11.4] GO:0043231//intracellular membrane-bounded organelle;GO:0045240 GO:0032550;GO:0004672//protein kinase activity GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0009063//cellular amino acid catabolic process gi|74178013|dbj|BAE29801.1|/0/unnamed protein product [Mus musculus] 53417 6916 1.063333333 0.863333333 -0.300604326 Down 0.210895483 Hif3a "hypoxia inducible factor 3, alpha subunit" K09096|1|0.0|1207|mmu:53417|hypoxia-inducible factor 3 alpha - - - - 381338 5077 0.87 1.073333333 0.303010882 Up 0.210895483 Lonrf2 LON peptidase N-terminal domain and ring finger 2 K03175|1|5e-07|60.5|mde:101890213|TNF receptor-associated factor 6 [EC:2.3.2.27];K12031|2|9e-07|59.7|ola:101166948|tripartite motif-containing protein 65;K10652|3|1e-06|59.3|mze:101484957|tripartite motif-containing protein 25 [EC:2.3.2.27];K12034|4|2e-06|58.9|xtr:734075|tripartite motif-containing protein 69 [EC:2.3.2.27];K16272|5|2e-06|58.5|pbi:103064512|E3 ubiquitin-protein ligase RNF135 [EC:2.3.2.27] - GO:0043169//cation binding - gi|568906653|ref|XP_006496186.1|/0/PREDICTED: LON peptidase N-terminal domain and RING finger protein 2 isoform X1 [Mus musculus] 19325 3531 45.44 43.16 -0.07426797 Down 0.210829666 Rab10 "RAB10, member RAS oncogene family" K07903|1|2e-111|407|pale:102889067|Ras-related protein Rab-10 GO:0005929//cilium;GO:0030666//endocytic vesicle membrane;GO:0030141//secretory granule;GO:0044432;GO:0043234//protein complex;GO:0010008//endosome membrane GO:0032550;GO:0017022//myosin binding GO:0032868//response to insulin;GO:0046677//response to antibiotic;GO:0007009//plasma membrane organization;GO:0007029//endoplasmic reticulum organization;GO:0006886//intracellular protein transport;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0008105//asymmetric protein localization;GO:0030010//establishment of cell polarity;GO:0006892//post-Golgi vesicle-mediated transport;GO:0090150//establishment of protein localization to membrane;GO:0001738//morphogenesis of a polarized epithelium;GO:0035556//intracellular signal transduction gi|7710086|ref|NP_057885.1|/1.31111e-110/ras-related protein Rab-10 [Mus musculus] 18508 3485 0.63 0.81 0.362570079 Up 0.210820264 Pax6 paired box 6 K08031|1|0.0|745|shr:100914594|paired box protein 6 GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0000785//chromatin;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0000785//chromatin;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0000785//chromatin;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0000785//chromatin;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0000785//chromatin;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0000785//chromatin;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0000785//chromatin "GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0019900//kinase binding;GO:0043566//structure-specific DNA binding;GO:0019904//protein domain specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0019900//kinase binding;GO:0043566//structure-specific DNA binding;GO:0019904//protein domain specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0019900//kinase binding;GO:0043566//structure-specific DNA binding;GO:0019904//protein domain specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0019900//kinase binding;GO:0043566//structure-specific DNA binding;GO:0019904//protein domain specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0019900//kinase binding;GO:0043566//structure-specific DNA binding;GO:0019904//protein domain specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0019900//kinase binding;GO:0043566//structure-specific DNA binding;GO:0019904//protein domain specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0019900//kinase binding;GO:0043566//structure-specific DNA binding;GO:0019904//protein domain specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0019900//kinase binding;GO:0043566//structure-specific DNA binding;GO:0019904//protein domain specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0044389//ubiquitin-like protein ligase binding" "GO:0021520//spinal cord motor neuron cell fate specification;GO:0021521//ventral spinal cord interneuron specification;GO:0007405//neuroblast proliferation;GO:0021917;GO:0001754//eye photoreceptor cell differentiation;GO:0021877//forebrain neuron fate commitment;GO:0016477//cell migration;GO:0021537//telencephalon development;GO:0021536//diencephalon development;GO:0009798//axis specification;GO:0050953//sensory perception of light stimulus;GO:0032446//protein modification by small protein conjugation;GO:0006935//chemotaxis;GO:0033500//carbohydrate homeostasis;GO:0021779//oligodendrocyte cell fate commitment;GO:0031076//embryonic camera-type eye development;GO:0007166//cell surface receptor signaling pathway;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0021903//rostrocaudal neural tube patterning;GO:0008285//negative regulation of cell proliferation;GO:0003310//pancreatic A cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030855//epithelial cell differentiation;GO:0040034//regulation of development, heterochronic;GO:0034613//cellular protein localization;GO:0006950//response to stress;GO:0007431//salivary gland development;GO:0009913//epidermal cell differentiation;GO:0001944//vasculature development;GO:0010721//negative regulation of cell development;GO:0021520//spinal cord motor neuron cell fate specification;GO:0021521//ventral spinal cord interneuron specification;GO:0007405//neuroblast proliferation;GO:0021917;GO:0001754//eye photoreceptor cell differentiation;GO:0021877//forebrain neuron fate commitment;GO:0016477//cell migration;GO:0021537//telencephalon development;GO:0021536//diencephalon development;GO:0009798//axis specification;GO:0050953//sensory perception of light stimulus;GO:0032446//protein modification by small protein conjugation;GO:0006935//chemotaxis;GO:0033500//carbohydrate homeostasis;GO:0021779//oligodendrocyte cell fate commitment;GO:0031076//embryonic camera-type eye development;GO:0007166//cell surface receptor signaling pathway;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0021903//rostrocaudal neural tube patterning;GO:0008285//negative regulation of cell proliferation;GO:0003310//pancreatic A cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030855//epithelial cell differentiation;GO:0040034//regulation of development, heterochronic;GO:0034613//cellular protein localization;GO:0006950//response to stress;GO:0007431//salivary gland development;GO:0009913//epidermal cell differentiation;GO:0001944//vasculature development;GO:0010721//negative regulation of cell development;GO:0021520//spinal cord motor neuron cell fate specification;GO:0021521//ventral spinal cord interneuron specification;GO:0007405//neuroblast proliferation;GO:0021917;GO:0001754//eye photoreceptor cell differentiation;GO:0021877//forebrain neuron fate commitment;GO:0016477//cell migration;GO:0021537//telencephalon development;GO:0021536//diencephalon development;GO:0009798//axis specification;GO:0050953//sensory perception of light stimulus;GO:0032446//protein modification by small protein conjugation;GO:0006935//chemotaxis;GO:0033500//carbohydrate homeostasis;GO:0021779//oligodendrocyte cell fate commitment;GO:0031076//embryonic camera-type eye development;GO:0007166//cell surface receptor signaling pathway;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0021903//rostrocaudal neural tube patterning;GO:0008285//negative regulation of cell proliferation;GO:0003310//pancreatic A cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030855//epithelial cell differentiation;GO:0040034//regulation of development, heterochronic;GO:0034613//cellular protein localization;GO:0006950//response to stress;GO:0007431//salivary gland development;GO:0009913//epidermal cell differentiation;GO:0001944//vasculature development;GO:0010721//negative regulation of cell development;GO:0021520//spinal cord motor neuron cell fate specification;GO:0021521//ventral spinal cord interneuron specification;GO:0007405//neuroblast proliferation;GO:0021917;GO:0001754//eye photoreceptor cell differentiation;GO:0021877//forebrain neuron fate commitment;GO:0016477//cell migration;GO:0021537//telencephalon development;GO:0021536//diencephalon development;GO:0009798//axis specification;GO:0050953//sensory perception of light stimulus;GO:0032446//protein modification by small protein conjugation;GO:0006935//chemotaxis;GO:0033500//carbohydrate homeostasis;GO:0021779//oligodendrocyte cell fate commitment;GO:0031076//embryonic camera-type eye development;GO:0007166//cell surface receptor signaling pathway;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0021903//rostrocaudal neural tube patterning;GO:0008285//negative regulation of cell proliferation;GO:0003310//pancreatic A cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030855//epithelial cell differentiation;GO:0040034//regulation of development, heterochronic;GO:0034613//cellular protein localization;GO:0006950//response to stress;GO:0007431//salivary gland development;GO:0009913//epidermal cell differentiation;GO:0001944//vasculature development;GO:0010721//negative regulation of cell development;GO:0021520//spinal cord motor neuron cell fate specification;GO:0021521//ventral spinal cord interneuron specification;GO:0007405//neuroblast proliferation;GO:0021917;GO:0001754//eye photoreceptor cell differentiation;GO:0021877//forebrain neuron fate commitment;GO:0016477//cell migration;GO:0021537//telencephalon development;GO:0021536//diencephalon development;GO:0009798//axis specification;GO:0050953//sensory perception of light stimulus;GO:0032446//protein modification by small protein conjugation;GO:0006935//chemotaxis;GO:0033500//carbohydrate homeostasis;GO:0021779//oligodendrocyte cell fate commitment;GO:0031076//embryonic camera-type eye development;GO:0007166//cell surface receptor signaling pathway;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0021903//rostrocaudal neural tube patterning;GO:0008285//negative regulation of cell proliferation;GO:0003310//pancreatic A cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030855//epithelial cell differentiation;GO:0040034//regulation of development, heterochronic;GO:0034613//cellular protein localization;GO:0006950//response to stress;GO:0007431//salivary gland development;GO:0009913//epidermal cell differentiation;GO:0001944//vasculature development;GO:0010721//negative regulation of cell development;GO:0021520//spinal cord motor neuron cell fate specification;GO:0021521//ventral spinal cord interneuron specification;GO:0007405//neuroblast proliferation;GO:0021917;GO:0001754//eye photoreceptor cell differentiation;GO:0021877//forebrain neuron fate commitment;GO:0016477//cell migration;GO:0021537//telencephalon development;GO:0021536//diencephalon development;GO:0009798//axis specification;GO:0050953//sensory perception of light stimulus;GO:0032446//protein modification by small protein conjugation;GO:0006935//chemotaxis;GO:0033500//carbohydrate homeostasis;GO:0021779//oligodendrocyte cell fate commitment;GO:0031076//embryonic camera-type eye development;GO:0007166//cell surface receptor signaling pathway;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0021903//rostrocaudal neural tube patterning;GO:0008285//negative regulation of cell proliferation;GO:0003310//pancreatic A cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030855//epithelial cell differentiation;GO:0040034//regulation of development, heterochronic;GO:0034613//cellular protein localization;GO:0006950//response to stress;GO:0007431//salivary gland development;GO:0009913//epidermal cell differentiation;GO:0001944//vasculature development;GO:0010721//negative regulation of cell development;GO:0021520//spinal cord motor neuron cell fate specification;GO:0021521//ventral spinal cord interneuron specification;GO:0007405//neuroblast proliferation;GO:0021917;GO:0001754//eye photoreceptor cell differentiation;GO:0021877//forebrain neuron fate commitment;GO:0016477//cell migration;GO:0021537//telencephalon development;GO:0021536//diencephalon development;GO:0009798//axis specification;GO:0006935//chemotaxis;GO:0033500//carbohydrate homeostasis;GO:0021779//oligodendrocyte cell fate commitment;GO:0031076//embryonic camera-type eye development;GO:0007166//cell surface receptor signaling pathway;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0021903//rostrocaudal neural tube patterning;GO:0008285//negative regulation of cell proliferation;GO:0003310//pancreatic A cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030855//epithelial cell differentiation;GO:0040034//regulation of development, heterochronic;GO:0034613//cellular protein localization;GO:0006950//response to stress;GO:0007431//salivary gland development;GO:0009913//epidermal cell differentiation;GO:0001944//vasculature development;GO:0021520//spinal cord motor neuron cell fate specification;GO:0021521//ventral spinal cord interneuron specification;GO:0007405//neuroblast proliferation;GO:0021917;GO:0001754//eye photoreceptor cell differentiation;GO:0021877//forebrain neuron fate commitment;GO:0016477//cell migration;GO:0021537//telencephalon development;GO:0021536//diencephalon development;GO:0009798//axis specification;GO:0050953//sensory perception of light stimulus;GO:0032446//protein modification by small protein conjugation;GO:0006935//chemotaxis;GO:0033500//carbohydrate homeostasis;GO:0021779//oligodendrocyte cell fate commitment;GO:0031076//embryonic camera-type eye development;GO:0007166//cell surface receptor signaling pathway;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0021903//rostrocaudal neural tube patterning;GO:0008285//negative regulation of cell proliferation;GO:0003310//pancreatic A cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030855//epithelial cell differentiation;GO:0040034//regulation of development, heterochronic;GO:0034613//cellular protein localization;GO:0006950//response to stress;GO:0007431//salivary gland development;GO:0009913//epidermal cell differentiation;GO:0001944//vasculature development;GO:0010721//negative regulation of cell development" "gi|149022827|gb|EDL79721.1|/0/paired box gene 6, isoform CRA_a [Rattus norvegicus]" 208144 4235 12.49333333 11.75333333 -0.088088478 Down 0.210773252 Dhx37 DEAH (Asp-Glu-Ala-His) box polypeptide 37 K14780|1|0.0|1988|mmu:208144|ATP-dependent RNA helicase DHX37/DHR1 [EC:3.6.4.13] - "GO:0032550;GO:0042623//ATPase activity, coupled" - gi|42600571|ref|NP_976064.1|/0/probable ATP-dependent RNA helicase DHX37 [Mus musculus] 66169 1126 17.79666667 18.84333333 0.082447148 Up 0.210641619 Tomm7 translocase of outer mitochondrial membrane 7 homolog (yeast) K17771|1|2e-24|115|ocu:100337985|mitochondrial import receptor subunit TOM7 GO:0031224//intrinsic component of membrane;GO:0005741//mitochondrial outer membrane GO:0008565//protein transporter activity;GO:0005488//binding GO:0006626//protein targeting to mitochondrion;GO:0019538//protein metabolic process gi|655837022|ref|XP_002713756.2|/1.41227e-23/PREDICTED: mitochondrial import receptor subunit TOM7 homolog [Oryctolagus cuniculus] 216011 2636 18.78666667 19.83333333 0.078218057 Up 0.210641619 Lrrc20 leucine rich repeat containing 20 K04240|1|2e-46|190|umr:103667792|neuropeptide FF receptor 1;K16340|2|2e-09|67.8|aag:AaeL_AAEL007111|PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16];K10641|3|2e-09|67.4|aga:AgaP_AGAP005053|E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27] - - - gi|545193937|ref|XP_001503777.2|/1.19238e-97/PREDICTED: leucine-rich repeat-containing protein 20 isoform X1 [Equus caballus] 18611 2477 45.75 43.54333333 -0.07131989 Down 0.210547595 Pea15a phosphoprotein enriched in astrocytes 15A K15604|1|8e-13|78.6|pps:100971215|protein lyl-1 GO:0015630//microtubule cytoskeleton GO:0005488//binding GO:0010829//negative regulation of glucose transport;GO:0014072//response to isoquinoline alkaloid;GO:0006915//apoptotic process;GO:0007165//signal transduction gi|744603535|ref|XP_010991404.1|/6.75336e-71/PREDICTED: astrocytic phosphoprotein PEA-15 [Camelus dromedarius] 14583 6248 2.693333333 2.393333333 -0.170371449 Down 0.210509985 Gfpt1 glutamine fructose-6-phosphate transaminase 1 K00820|1|0.0|1335|mmu:14583|glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16] GO:0044444//cytoplasmic part GO:0031406//carboxylic acid binding;GO:0070548 GO:0006041//glucosamine metabolic process;GO:0032868//response to insulin;GO:0034285;GO:0009064//glutamine family amino acid metabolic process;GO:0006487//protein N-linked glycosylation;GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0005978//glycogen biosynthetic process;GO:0051260//protein homooligomerization;GO:0030968//endoplasmic reticulum unfolded protein response gi|7305085|ref|NP_038556.1|/0/glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 [Mus musculus] 22153 2246 2.793333333 2.49 -0.165842001 Down 0.210509985 Tubb4a "tubulin, beta 4A class IVA" K07375|1|0.0|830|ssc:100736584|tubulin beta GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044297//cell body;GO:0033267;GO:0044444//cytoplasmic part GO:0005198//structural molecule activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0006458//'de novo' protein folding;GO:0044772//mitotic cell cycle phase transition;GO:0043623//cellular protein complex assembly;GO:0009154//purine ribonucleotide catabolic process gi|574584811|ref|NP_001276056.1|/0/tubulin beta-4A chain isoform 2 [Homo sapiens] 72656 3476.47 3.09 2.77 -0.157720862 Down 0.210481778 Ints8 integrator complex subunit 8 K13145|1|0.0|1925|mmu:72656|integrator complex subunit 8 "GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0016591//DNA-directed RNA polymerase II, holoenzyme" GO:0005488//binding;GO:0005488//binding GO:0016073//snRNA metabolic process;GO:0016073//snRNA metabolic process gi|227430329|ref|NP_835213.3|/0/integrator complex subunit 8 [Mus musculus] 270096 4989.07 3.166666667 2.843333333 -0.155381772 Down 0.210481778 Mon1b "MON1 homolog B, secretory traffciking associated" K20195|1|0.0|951|mmu:270096|vacuolar fusion protein MON1 - - - gi|27370524|ref|NP_766603.1|/0/vacuolar fusion protein MON1 homolog B [Mus musculus] 59002 1600 5.963333333 6.453333333 0.113925565 Up 0.210462973 Wrap73 "WD repeat containing, antisense to Trp73" K18598|1|9e-07|57.8|amj:102570515|echinoderm microtubule-associated protein-like 6 GO:0005815//microtubule organizing center - - gi|70778726|ref|NP_067474.2|/0/WD repeat-containing protein WRAP73 [Mus musculus] 319965 3286 6.923333333 6.436666667 -0.105153052 Down 0.210462973 Cc2d1b coiled-coil and C2 domain containing 1B K18260|1|0.0|1306|mmu:319965|coiled-coil and C2 domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding" "GO:0006351//transcription, DNA-templated" "gi|148698789|gb|EDL30736.1|/0/coiled-coil and C2 domain containing 1B, isoform CRA_b, partial [Mus musculus]" 74455 2929 0.97 0.776666667 -0.320689198 Down 0.210462973 Nsun6 NOL1/NOP2/Sun domain family member 6 K14835|1|1e-22|111|bmy:Bm1_29315|ribosomal RNA methyltransferase Nop2 [EC:2.1.1.-] - GO:0003676//nucleic acid binding;GO:0016741;GO:0003676//nucleic acid binding;GO:0016741;GO:0003676//nucleic acid binding;GO:0016741;GO:0003676//nucleic acid binding;GO:0016741 GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process "gi|148676130|gb|EDL08077.1|/0/NOL1/NOP2/Sun domain family 6, isoform CRA_b, partial [Mus musculus]" 19895 1789 5.07 5.503333333 0.118319967 Up 0.210434766 Rpia ribose 5-phosphate isomerase A K01807|1|6e-148|526|mmu:19895|ribose 5-phosphate isomerase A [EC:5.3.1.6] GO:0043227//membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0030246//carbohydrate binding;GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses" GO:0006098//pentose-phosphate shunt gi|94536844|ref|NP_033101.2|/5.04826e-147/ribose-5-phosphate isomerase [Mus musculus] 67008 3436 11.74666667 12.47333333 0.086595634 Up 0.21036895 Yae1d1 Yae1 domain containing 1 - - - - gi|13385398|ref|NP_080180.1|/5.50188e-122/yae1 domain-containing protein 1 [Mus musculus] 228602 6658.17 12.10333333 11.37333333 -0.089749283 Down 0.21036895 4930402H24Rik RIKEN cDNA 4930402H24 gene K01855|1|2e-30|139|smm:Smp_171830|tRNA pseudouridine38/39 synthase [EC:5.4.99.45] - - - "gi|148696343|gb|EDL28290.1|/0/RIKEN cDNA 4930402H24, partial [Mus musculus]" 67474 3432 8.736666667 8.17 -0.096746869 Down 0.21033134 Snap29 synaptosomal-associated protein 29 K08509|1|4e-134|482|mmu:67474|synaptosomal-associated protein 29 GO:0016020//membrane;GO:0031981//nuclear lumen;GO:0042995//cell projection GO:0000149//SNARE binding GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport gi|139948568|ref|NP_075837.3|/3.10656e-133/synaptosomal-associated protein 29 [Mus musculus] 11308 3501.58 8.57 8.003333333 -0.098694207 Down 0.21033134 Abi1 abl-interactor 1 K05751|1|8e-150|534|acs:100566563|abl interactor 2 - - - - 69091 6890 8.283333333 8.85 0.095466009 Up 0.21033134 Vps26b VPS26 retromer complex component B K18466|1|0.0|672|rno:300472|vacuolar protein sorting-associated protein 26 GO:0012505//endomembrane system;GO:0044444//cytoplasmic part - GO:0044765//single-organism transport;GO:0045184//establishment of protein localization gi|29825827|ref|NP_821170.1|/0/vacuolar protein sorting-associated protein 26B [Mus musculus] 19134 4482 3.856666667 3.5 -0.139999537 Down 0.210321938 Prpf4b pre-mRNA processing factor 4B K08827|1|0.0|1256|mmu:19134|serine/threonine-protein kinase PRP4 [EC:2.7.11.1] - - - - 78752 3676 3.946666667 3.59 -0.136650831 Down 0.210321938 Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 K00746|1|0.0|1026|mmu:78752|chondroitin sulfate N-acetylgalactosaminyltransferase 1/2 [EC:2.4.1.174 2.4.1.175] GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane GO:0043169//cation binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0006024//glycosaminoglycan biosynthetic process;GO:0030166//proteoglycan biosynthetic process gi|31560032|ref|NP_084441.3|/0/chondroitin sulfate N-acetylgalactosaminyltransferase 2 [Mus musculus] 71801 2956 3.416666667 3.776666667 0.144523951 Up 0.210321938 Plekhf2 "pleckstrin homology domain containing, family F (with FYVE domain) member 2" "K05724|1|1e-27|127|lcm:102358796|FYVE, RhoGEF and PH domain containing 5/6" "GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0008289//lipid binding;GO:0043169//cation binding - gi|29611667|ref|NP_780384.1|/2.80819e-135/pleckstrin homology domain-containing family F member 2 [Mus musculus] 14555 2809 48.35333333 46.18333333 -0.066243043 Down 0.210303133 Gpd1 glycerol-3-phosphate dehydrogenase 1 (soluble) K00006|1|0.0|703|mmu:14555|glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0016901//oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0000166//nucleotide binding;GO:0048037//cofactor binding" GO:0055114//oxidation-reduction process;GO:0006072//glycerol-3-phosphate metabolic process;GO:0019674//NAD metabolic process;GO:0034612//response to tumor necrosis factor;GO:0006006//glucose metabolic process;GO:0044255//cellular lipid metabolic process;GO:0051591//response to cAMP gi|60360470|dbj|BAD90479.1|/0/mKIAA4010 protein [Mus musculus] 58229 2754 0.486666667 0.336666667 -0.531613076 Down 0.21029373 Efcc1 EF hand and coiled-coil domain containing 1 K07930|1|4e-32|142|mgp:100542335|Ras-related protein Rab-43;K08835|2|9e-11|72.0|tru:101076612|serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1] - - - gi|228008356|ref|NP_001153169.1|/0/EF-hand and coiled-coil domain-containing protein 1 [Mus musculus] 104884 2073 4.04 4.433333333 0.134036547 Up 0.210256121 Tdp1 tyrosyl-DNA phosphodiesterase 1 K10862|1|0.0|1219|mmu:104884|tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-] GO:0043231//intracellular membrane-bounded organelle GO:0043566//structure-specific DNA binding;GO:0004518//nuclease activity;GO:0070259 GO:0006281//DNA repair gi|162417986|ref|NP_082630.2|/0/tyrosyl-DNA phosphodiesterase 1 [Mus musculus] 109205 4994 4.276666667 4.67 0.126935785 Up 0.210256121 Sobp sine oculis-binding protein homolog (Drosophila) K02367|1|9e-09|66.2|pxy:105394758|glucuronyl/N-acetylglucosaminyl transferase EXT2 [EC:2.4.1.224 2.4.1.225] - GO:0032183//SUMO binding GO:0042471//ear morphogenesis;GO:0044708//single-organism behavior;GO:0050954//sensory perception of mechanical stimulus gi|117938305|ref|NP_780616.4|/0/sine oculis-binding protein homolog [Mus musculus] 100504701 2074 4.463333333 4.073333333 -0.131911676 Down 0.210256121 Gm20362 "predicted gene, 20362" - - - - - 668166 5623 0.543333333 0.716666667 0.399464695 Up 0.210246719 Zxdb "zinc finger, X-linked, duplicated B" K10485|1|7e-79|299|myd:102773583|BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1) - - - - 26904 1433 0.14 0.04 -1.807354922 Down 0.210246719 Sh2d1b1 SH2 domain containing 1B1 K07989|1|4e-73|278|mmu:26904|EWS/FLI1 activated transcript 2 GO:0044464 "GO:0060090//binding, bridging;GO:0045309//protein phosphorylated amino acid binding" GO:0001934//positive regulation of protein phosphorylation;GO:0002228//natural killer cell mediated immunity;GO:0002767//immune response-inhibiting cell surface receptor signaling pathway;GO:0030101//natural killer cell activation;GO:0001818//negative regulation of cytokine production;GO:0001911;GO:0002263//cell activation involved in immune response;GO:0001933//negative regulation of protein phosphorylation;GO:0031349//positive regulation of defense response gi|148747582|ref|NP_036139.3|/3.04091e-72/SH2 domain-containing protein 1B [Mus musculus] 12671 3168 0.036666667 0.133333333 1.862496476 Up 0.210246719 Chrm3 "cholinergic receptor, muscarinic 3, cardiac" K04131|1|0.0|1115|mmu:12671|muscarinic acetylcholine receptor M3 - - - - 338521 2492 0.14 0.04 -1.807354922 Down 0.210246719 Fa2h fatty acid 2-hydroxylase K19703|1|0.0|726|mmu:338521|4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase [EC:1.14.18.6] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016491//oxidoreductase activity GO:0006631//fatty acid metabolic process;GO:0006643//membrane lipid metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0042633//hair cycle;GO:0022010//central nervous system myelination;GO:0051234//establishment of localization;GO:0022011//myelination in peripheral nervous system;GO:0008283//cell proliferation gi|158517893|ref|NP_835187.2|/0/fatty acid 2-hydroxylase [Mus musculus] 14453 2137 1.223333333 1.013333333 -0.271708739 Down 0.210180902 Gas2 growth arrest specific 2 K10382|1|4e-08|62.8|obi:106880784|dystonin;K19827|5|3e-07|59.7|hro:HELRODRAFT_79805|microtuble-actin crosslinking factor 1 GO:0043232 - GO:0022604//regulation of cell morphogenesis;GO:0012501//programmed cell death;GO:0022402//cell cycle process gi|6679943|ref|NP_032113.1|/1.00313e-160/growth arrest-specific protein 2 [Mus musculus] 241311 6568.65 1.35 1.133333333 -0.252387162 Down 0.210180902 Zbtb34 zinc finger and BTB domain containing 34 K10508|1|0.0|991|mmu:241311|zinc finger and BTB domain-containing protein 34 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding - gi|50511227|dbj|BAD32599.1|/0/mKIAA1993 protein [Mus musculus] 67231 1936 18.79666667 19.82666667 0.076965304 Up 0.210171499 Tbc1d20 "TBC1 domain family, member 20" K20372|1|0.0|685|mmu:67231|TBC1 domain family member 20 GO:0031224//intrinsic component of membrane;GO:0044464 - - "gi|148674010|gb|EDL05957.1|/0/TBC1 domain family, member 20, isoform CRA_c, partial [Mus musculus]" 71929 2881 17.96333333 18.99666667 0.080691206 Up 0.210171499 Tmem123 transmembrane protein 123 K06546|1|4e-08|63.2|dpe:Dper_GL17973|CD164 antigen GO:0009986//cell surface;GO:0044425 - GO:0070265//necrotic cell death gi|19526938|ref|NP_598500.1|/2.12468e-71/porimin precursor [Mus musculus] 51800 1575 1.446666667 1.683333333 0.218588345 Up 0.21013389 Bok BCL2-related ovarian killer K02561|1|1e-117|426|rno:29884|Bcl-2-related ovarian killer protein - - - - 66197 694 1.686666667 1.45 -0.218121984 Down 0.21013389 Cks2 CDC28 protein kinase regulatory subunit 2 K02219|1|4e-42|173|shr:100915745|cyclin-dependent kinase regulatory subunit CKS1 - "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019887//protein kinase regulator activity" GO:0007126//meiotic nuclear division;GO:0051726//regulation of cell cycle;GO:0048017//inositol lipid-mediated signaling;GO:0000226//microtubule cytoskeleton organization;GO:0006796//phosphate-containing compound metabolic process "gi|148709157|gb|EDL41103.1|/9.19716e-54/mCG1274, isoform CRA_b, partial [Mus musculus]" 21898 7891 1.683333333 1.446666667 -0.218588345 Down 0.21013389 Tlr4 toll-like receptor 4 K10160|1|0.0|1618|mmu:21898|toll-like receptor 4 - - - - 654802 568 0.19 0.083333333 -1.189033824 Down 0.210021061 1700105P06Rik RIKEN cDNA 1700105P06 gene - - - - - 214084 3803 0.436666667 0.596666667 0.450392776 Up 0.209992854 Slc18a2 "solute carrier family 18 (vesicular monoamine), member 2" "K08155|1|0.0|919|mmu:214084|MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2" GO:0030141//secretory granule;GO:0044297//cell body;GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle;GO:0033267 GO:0005515//protein binding;GO:0005275//amine transmembrane transporter activity GO:0014075//response to amine;GO:0007275//multicellular organism development;GO:0015837//amine transport;GO:0015695//organic cation transport;GO:0033500//carbohydrate homeostasis;GO:0015893//drug transport;GO:0006836//neurotransmitter transport;GO:0051384//response to glucocorticoid;GO:0016192//vesicle-mediated transport;GO:0010038//response to metal ion;GO:0030072//peptide hormone secretion;GO:0044767//single-organism developmental process;GO:0006950//response to stress;GO:0060359//response to ammonium ion;GO:0044708//single-organism behavior "gi|148669876|gb|EDL01823.1|/0/solute carrier family 18 (vesicular monoamine), member 2, partial [Mus musculus]" 78312 365 0.59 0.433333333 -0.445237737 Down 0.209992854 1810041H14Rik RIKEN cDNA 1810041H14 gene - - - - - 100042166 2310 0.433333333 0.593333333 0.453365618 Up 0.209992854 Gm3704 predicted gene 3704 - - - - - 76915 874 0.59 0.433333333 -0.445237737 Down 0.209992854 Mnd1 meiotic nuclear divisions 1 K11997|1|5e-102|372|ptr:461550|tripartite motif-containing protein 2/3 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process;GO:0022403 gi|240848585|ref|NP_084073.2|/1.53054e-111/meiotic nuclear division protein 1 homolog [Mus musculus] 14065 1762 0.25 0.39 0.641546029 Up 0.209927037 F2rl3 coagulation factor II (thrombin) receptor-like 3 K04236|1|0.0|676|mmu:14065|coagulation factor II (thrombin) receptor-like 3 GO:0016021//integral component of membrane GO:0008528//G-protein coupled peptide receptor activity GO:0001775//cell activation;GO:0007599//hemostasis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0033363//secretory granule organization;GO:0006950//response to stress;GO:0010524//positive regulation of calcium ion transport into cytosol gi|31982379|ref|NP_032001.2|/0/proteinase-activated receptor 4 precursor [Mus musculus] 13669 5176 18.79 17.77 -0.080521385 Down 0.209851818 Eif3a "eukaryotic translation initiation factor 3, subunit A" K03254|1|0.0|1405|mmu:13669|translation initiation factor 3 subunit A - - - gi|50510383|dbj|BAD32177.1|/0/mKIAA0139 protein [Mus musculus] 22245 1966 10.75 11.47333333 0.093947937 Up 0.209833014 Uck1 uridine-cytidine kinase 1 K00876|1|7e-145|516|mmu:22245|uridine kinase [EC:2.7.1.48] - GO:0032550;GO:0019206//nucleoside kinase activity GO:0006222//UMP biosynthetic process;GO:0006241//CTP biosynthetic process gi|148676584|gb|EDL08531.1|/1.88467e-158/uridine-cytidine kinase 1 [Mus musculus] 171543 4654 1.633333333 1.883333333 0.205469118 Up 0.209814209 Bmf BCL2 modifying factor K17460|1|6e-154|548|mmu:171543|Bcl-2-modifying factor GO:0015629//actin cytoskeleton GO:0005488//binding GO:0006915//apoptotic process;GO:0010822//positive regulation of mitochondrion organization;GO:0032461//positive regulation of protein oligomerization gi|902967398|ref|NP_001298069.1|/4.27987e-109/bcl-2-modifying factor isoform 2 [Mus musculus] 170763 2710 1.633333333 1.886666667 0.208020304 Up 0.209814209 Zfp87 zinc finger protein 87 K09228|1|0.0|1175|mmu:170763|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding - gi|22165394|ref|NP_573491.2|/0/zinc finger protein 87 [Mus musculus] 75610 548 0.196666667 0.086666667 -1.182203331 Down 0.209757795 2010109A12Rik RIKEN cDNA 2010109A12 gene - - - - gi|361050356|ref|NP_083639.1|/1.35906e-64/uncharacterized protein LOC75610 [Mus musculus] 76880 1315 0.043333333 0.143333333 1.725825037 Up 0.209654368 6430411K18Rik RIKEN cDNA 6430411K18 gen K10798|1|4e-23|111|dre:558045|poly [ADP-ribose] polymerase [EC:2.4.2.30];K04612|2|2e-18|96.3|mze:101472134|calcium-sensing receptor;K00025|3|7e-17|90.9|soc:105204759|malate dehydrogenase [EC:1.1.1.37];K16803|4|7e-15|84.3|pxy:105395769|cytoskeleton-associated protein 5;K08029|5|2e-12|76.3|api:100166494|homeobox protein Nkx-2.2 - - - - 18676 5260 19.18666667 18.18 -0.077751892 Down 0.209644966 Phf2 PHD finger protein 2 K19414|1|0.0|1749|mmu:18676|lysine-specific demethylase PHF2 [EC:1.14.11.-] GO:0031981//nuclear lumen "GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0003712//transcription cofactor activity;GO:0032452//histone demethylase activity;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0070076//histone lysine demethylation;GO:0000183//chromatin silencing at rDNA;GO:0044767//single-organism developmental process gi|31543476|ref|NP_035208.2|/0/lysine-specific demethylase PHF2 [Mus musculus] 100628593 79 17.07333333 18.08666667 0.083181795 Up 0.209644966 Mir5125 microRNA 5125 - - - - - 245469 3991 0.733333333 0.56 -0.389042291 Down 0.209607356 Pdzd4 PDZ domain containing 4 K15682|1|0.0|1124|mmu:245469|ligand of Numb protein X 3/4 [EC:2.3.2.27] - - - gi|71274176|ref|NP_001025039.1|/0/PDZ domain-containing protein 4 isoform 1 [Mus musculus] 75646 4843 2.166666667 1.893333333 -0.194548788 Down 0.209588552 Rai14 retinoic acid induced 14 K15502|1|7e-31|139|obi:106869704|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 - - gi|37360330|dbj|BAC98143.1|/0/mKIAA1334 protein [Mus musculus] 21834 5997 2.16 1.893333333 -0.190102883 Down 0.209588552 Thrb thyroid hormone receptor beta K08362|1|0.0|899|cfr:102523463|thyroid hormone receptor beta GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0042802//identical protein binding;GO:0003682//chromatin binding;GO:0043566//structure-specific DNA binding;GO:0046914//transition metal ion binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0042802//identical protein binding;GO:0003682//chromatin binding;GO:0043566//structure-specific DNA binding" GO:0009653//anatomical structure morphogenesis;GO:0002062//chondrocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0045924//regulation of female receptivity;GO:0009755//hormone-mediated signaling pathway;GO:0008283//cell proliferation;GO:0044057;GO:0001503//ossification;GO:0019218//regulation of steroid metabolic process;GO:0050954//sensory perception of mechanical stimulus;GO:0007619//courtship behavior;GO:0009653//anatomical structure morphogenesis;GO:0002062//chondrocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0045924//regulation of female receptivity;GO:0009755//hormone-mediated signaling pathway;GO:0008283//cell proliferation;GO:0044057;GO:0001503//ossification;GO:0019218//regulation of steroid metabolic process;GO:0050954//sensory perception of mechanical stimulus;GO:0009790//embryo development;GO:0007619//courtship behavior gi|164663877|ref|NP_001106888.1|/0/thyroid hormone receptor beta isoform 1 [Mus musculus] 20924 3561 45.25666667 43.19333333 -0.067321671 Down 0.209579149 Supt5 suppressor of Ty 5 K15172|1|0.0|1918|mmu:20924|transcription elongation factor SPT5 GO:0008023//transcription elongation factor complex GO:0046983//protein dimerization activity "GO:0010508//positive regulation of autophagy;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0006368//transcription elongation from RNA polymerase II promoter" "gi|35505439|gb|AAH57449.1|/0/Supt5h protein, partial [Mus musculus]" 16880 8667.22 7.97 8.533333333 0.09852968 Up 0.209485125 Lifr leukemia inhibitory factor receptor K05058|1|0.0|2185|mmu:16880|leukemia inhibitory factor receptor GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004897//ciliary neurotrophic factor receptor activity;GO:0005126//cytokine receptor binding;GO:0046983//protein dimerization activity;GO:0004897//ciliary neurotrophic factor receptor activity;GO:0005126//cytokine receptor binding;GO:0046983//protein dimerization activity GO:0031175//neuron projection development;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0009887//organ morphogenesis;GO:0019221//cytokine-mediated signaling pathway;GO:0008283//cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0031175//neuron projection development;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0009887//organ morphogenesis;GO:0019221//cytokine-mediated signaling pathway;GO:0008283//cell proliferation;GO:0043066//negative regulation of apoptotic process gi|7305235|ref|NP_038612.1|/0/leukemia inhibitory factor receptor isoform 1 precursor [Mus musculus] 545207 4255.4 0.676666667 0.86 0.345891338 Up 0.209475723 E130008D07Rik RIKEN cDNA E130008D07 gene - - - - - 213819 3760 5.843333333 6.32 0.113132968 Up 0.209428711 Casd1 CAS1 domain containing 1 - GO:0031224//intrinsic component of membrane - - gi|37620157|ref|NP_663373.2|/0/CAS1 domain-containing protein 1 precursor [Mus musculus] 66660 3604.14 5.796666667 6.273333333 0.114008695 Up 0.209428711 Sltm "SAFB-like, transcription modulator" K00753|1|1e-24|118|pxy:105390580|glycoprotein 3-alpha-L-fucosyltransferase [EC:2.4.1.214];K19538|2|8e-12|75.9|fab:101806355|retinitis pigmentosa 1 GO:0031981//nuclear lumen GO:0003676//nucleic acid binding "GO:0012501//programmed cell death;GO:0006351//transcription, DNA-templated" gi|62243815|ref|NP_079966.2|/0/SAFB-like transcription modulator isoform a [Mus musculus] 24115 2087 0.05 0.153333333 1.61667136 Up 0.209400504 Best1 bestrophin 1 K13878|1|0.0|1106|mmu:24115|bestrophin-1 GO:0044459;GO:0034702//ion channel complex GO:0005253//anion channel activity GO:0007601//visual perception;GO:0006821//chloride transport;GO:0006816//calcium ion transport gi|160333218|ref|NP_036043.2|/0/bestrophin-1 [Mus musculus] 194744 1001 0.153333333 0.05 -1.61667136 Down 0.209400504 Slc25a43 "solute carrier family 25, member 43" "K15120|1|0.0|659|mmu:194744|solute carrier family 25, member 43" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763 gi|148235204|ref|NP_001078966.1|/0/solute carrier family 25 member 43 [Mus musculus] 100504112 1051 0.146666667 0.046666667 -1.652076697 Down 0.209400504 Ccer2 coiled-coil glutamate-rich protein 2 - - - - - 26456 4310 0.046666667 0.146666667 1.652076697 Up 0.209400504 Sema4g "sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G" K06521|1|0.0|1470|mmu:26456|semaphorin 4 GO:0031224//intrinsic component of membrane - GO:0048731//system development;GO:0048869//cellular developmental process gi|6755462|ref|NP_036106.1|/0/semaphorin-4G precursor [Mus musculus] 69193 1031 0.15 0.046666667 -1.684498174 Down 0.209400504 Platr10 pluripotency associated transcript 10 - GO:0043005//neuron projection;GO:0044421 GO:0032934//sterol binding;GO:0042802//identical protein binding;GO:0071813//lipoprotein particle binding GO:0009611//response to wounding;GO:0010742//macrophage derived foam cell differentiation;GO:0051592//response to calcium ion;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0043623//cellular protein complex assembly;GO:0097305//response to alcohol;GO:0010976//positive regulation of neuron projection development;GO:0010883//regulation of lipid storage "gi|148683526|gb|EDL15473.1|/2.89315e-57/mCG145237, partial [Mus musculus]" 434438 2878 0.873333333 1.07 0.293006486 Up 0.209391102 Ccdc36 coiled-coil domain containing 36 - - - - "gi|35193124|gb|AAH58624.1|/0/Ccdc36 protein, partial [Mus musculus]" 233977 5235.86 12.32666667 11.61333333 -0.086000601 Down 0.209268871 Ppfia1 "protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1" K20478|1|1e-16|92.8|mdo:100013897|golgin subfamily B member 1 - - - gi|189491857|ref|NP_001028491.1|/0/liprin-alpha-1 isoform B [Mus musculus] 72750 5534 11.67333333 10.96 -0.090968785 Down 0.209268871 Fam117b "family with sequence similarity 117, member B" "K15275|1|3e-50|204|apla:101803377|solute carrier family 35 (UDP-galactose transporter), member B1" - - - gi|83582792|ref|NP_001032814.1|/0/protein FAM117B [Mus musculus] 20811 2547 0.313333333 0.18 -0.79970135 Down 0.209268871 Srms src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites K08895|1|0.0|991|mmu:20811|tyrosine-protein kinase Srms [EC:2.7.10.2] - GO:0004713//protein tyrosine kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process "gi|148675448|gb|EDL07395.1|/0/src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites, partial [Mus musculus]" 104771 1970.07 11.13 11.84333333 0.089621595 Up 0.209268871 Jkamp JNK1/MAPK8-associated membrane protein - GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0044389//ubiquitin-like protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0035966//response to topologically incorrect protein;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0035966//response to topologically incorrect protein "gi|148704594|gb|EDL36541.1|/8.98196e-169/RIKEN cDNA 1200003C05, isoform CRA_a, partial [Mus musculus]" 74480 6259.3 12.32666667 11.61666667 -0.085586569 Down 0.209268871 Samd4 sterile alpha motif domain containing 4 - GO:0043005//neuron projection;GO:0044424;GO:0042995//cell projection;GO:0043005//neuron projection GO:0045182//translation regulator activity;GO:0045182//translation regulator activity;GO:0045182//translation regulator activity GO:0006412//translation;GO:0006412//translation;GO:0006412//translation gi|58037381|ref|NP_083242.1|/0/protein Smaug homolog 1 isoform 2 [Mus musculus] 50780 3750.9 18.66666667 19.66333333 0.075043582 Up 0.209250066 Rgs3 regulator of G-protein signaling 3 K07524|1|0.0|1765|mmu:50780|regulator of G-protein signalling 3 - - - "gi|148699184|gb|EDL31131.1|/0/mCG145490, partial [Mus musculus]" 68755 1202 17.92666667 16.92333333 -0.083093495 Down 0.209250066 Cgrrf1 cell growth regulator with ring finger domain 1 K15693|1|8e-07|57.4|mze:101468268|RING finger protein 26 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding GO:0016049//cell growth;GO:0022402//cell cycle process "gi|148688780|gb|EDL20727.1|/0/cell growth regulator with ring finger domain 1, isoform CRA_b, partial [Mus musculus]" 319719 4811 0.443333333 0.603333333 0.444563452 Up 0.209240663 Simc1 SUMO-interacting motifs containing 1 "K14713|1|6e-32|143|pss:102454955|solute carrier family 39 (zinc transporter), member 7" - - - gi|171184441|ref|NP_795961.3|/0/SUMO-interacting motif-containing protein 1 [Mus musculus] 65107 3013 41.80333333 43.80666667 0.067532456 Up 0.20914664 Lrp10 low-density lipoprotein receptor-related protein 10 K20050|1|0.0|1119|mmu:65107|low-density lipoprotein receptor-related protein 3/10/12 GO:0031224//intrinsic component of membrane GO:0030228//lipoprotein particle receptor activity GO:0010876//lipid localization;GO:0043583//ear development;GO:0044238//primary metabolic process gi|32450416|gb|AAH54447.1|/0/Low-density lipoprotein receptor-related protein 10 [Mus musculus] 73204 1164 1.613333333 1.38 -0.22537628 Down 0.20914664 3110056K07Rik RIKEN cDNA 3110056K07 gene - - - - - 320784 1293.38 1.34 1.573333333 0.231591358 Up 0.20914664 C230072F16Rik RIKEN cDNA C230072F16 gene - - - - - 69906 2945 1.516666667 1.29 -0.233532979 Down 0.20914664 Slc25a32 "solute carrier family 25, member 32" "K15115|1|1e-172|609|mmu:69906|solute carrier family 25 (mitochondrial folate transporter), member 32" GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0051234//establishment of localization gi|168480117|ref|NP_765990.2|/1.08631e-171/mitochondrial folate transporter/carrier [Mus musculus] 17754 11553 1.55 1.323333333 -0.228091709 Down 0.20914664 Map1a microtubule-associated protein 1 A K10429|1|0.0|4616|mmu:17754|microtubule-associated protein 1 GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0007019//microtubule depolymerization;GO:0050954//sensory perception of mechanical stimulus;GO:0007019//microtubule depolymerization;GO:0050954//sensory perception of mechanical stimulus gi|124244033|ref|NP_115769.1|/0/microtubule-associated protein 1A isoform 1 [Mus musculus] 100038353 2301 1.263333333 1.056666667 -0.257715008 Down 0.209118432 Gm10532 predicted gene 10532 - - - - - 240063 3549 1.073333333 1.286666667 0.261540159 Up 0.209118432 Zfp811 zinc finger protein 811 K09228|1|0.0|873|cge:103161110|KRAB domain-containing zinc finger protein - - - - 21371 503 41.57333333 43.56666667 0.067566308 Up 0.209118432 Tbca tubulin cofactor A K17292|1|1e-30|134|mmu:21371|tubulin-specific chaperone A GO:0044424 - - gi|914912529|ref|XP_005329041.2|/4.84925e-30/PREDICTED: tubulin-specific chaperone A [Ictidomys tridecemlineatus] 12343 2015 42.81 40.83 -0.068318268 Down 0.209033811 Capza2 "capping protein (actin filament) muscle Z-line, alpha 2" "K10364|1|2e-155|551|rno:493810|capping protein (actin filament) muscle Z-line, alpha" GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding GO:0030835//negative regulation of actin filament depolymerization gi|6671672|ref|NP_031630.1|/1.70663e-154/F-actin-capping protein subunit alpha-2 [Mus musculus] 58198 5275 0.093333333 0.206666667 1.146841388 Up 0.209024409 Sall1 sal-like 1 (Drosophila) K19871|1|0.0|2228|mmu:58198|sal-like protein - - - - 12349 1807 3.346666667 3.013333333 -0.151364592 Down 0.208996201 Car2 carbonic anhydrase 2 K18245|1|3e-154|547|mmu:12349|carbonic anhydrase 2 [EC:4.2.1.1] GO:0043005//neuron projection;GO:0044421;GO:0044459;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0043168//anion binding;GO:0016836//hydro-lyase activity GO:0032846;GO:0048729//tissue morphogenesis;GO:0006885//regulation of pH;GO:0044237//cellular metabolic process;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0042476//odontogenesis;GO:0048545//response to steroid hormone;GO:0015711//organic anion transport;GO:0044710;GO:0010038//response to metal ion;GO:0009628//response to abiotic stimulus;GO:0015669 gi|157951596|ref|NP_033931.4|/2.80693e-153/carbonic anhydrase 2 [Mus musculus] 23794 8104 3.4 3.066666667 -0.148863386 Down 0.208996201 Adamts5 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)" K08620|1|0.0|1742|mmu:23794|a disintegrin and metalloproteinase with thrombospondin motifs 5 [EC:3.4.24.-] GO:0031012//extracellular matrix;GO:0031981//nuclear lumen GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway gi|125490361|ref|NP_035912.2|/0/A disintegrin and metalloproteinase with thrombospondin motifs 5 precursor [Mus musculus] 216760 4862.25 3.133333333 3.466666667 0.145850866 Up 0.208996201 Mfap3 microfibrillar-associated protein 3 - - - - - 790910 3347 0.403333333 0.263333333 -0.615082489 Down 0.208892775 Gm11201 predicted gene 11201 K14958|1|2e-12|77.8|pale:102878203|kinase suppressor of Ras 1 - - - - 76572 1472 0.266666667 0.41 0.62058641 Up 0.208892775 Rbmxl2 "RNA binding motif protein, X-linked-like 2" K12885|1|3e-114|414|mmu:76572|heterogeneous nuclear ribonucleoprotein G GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0000398//mRNA splicing, via spliceosome" "gi|65301143|ref|NP_083936.1|/2.82545e-113/RNA-binding motif protein, X-linked-like-2 [Mus musculus] " 14764 2644 0.393333333 0.256666667 -0.615856509 Down 0.208892775 Ptgdr2 prostaglandin D2 receptor 2 K06715|1|0.0|660|mmu:14764|G protein-coupled receptor 44 GO:0044464;GO:0016021//integral component of membrane GO:0004955//prostaglandin receptor activity;GO:0008528//G-protein coupled peptide receptor activity GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0019932//second-messenger-mediated signaling;GO:0042221//response to chemical gi|6753528|ref|NP_034092.1|/0/prostaglandin D2 receptor 2 [Mus musculus] 72543 4995 11.38666667 10.68333333 -0.091983618 Down 0.208845763 Mvb12b multivesicular body subunit 12B K12186|1|4e-162|575|rno:362118|ESCRT-I complex subunit MVB12 GO:0005770//late endosome - GO:0045184//establishment of protein localization gi|47847382|dbj|BAD21363.1|/7.18106e-174/mFLJ00022 protein [Mus musculus] 106504 3288 11.76 11.06 -0.088536675 Down 0.208845763 Stk38 serine/threonine kinase 38 K08790|1|0.0|949|mmu:106504|serine/threonine kinase 38 [EC:2.7.11.1] GO:0016020//membrane;GO:0035097//histone methyltransferase complex GO:0032550;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0046872//metal ion binding GO:0043405//regulation of MAP kinase activity gi|568998439|ref|XP_006523449.1|/0/PREDICTED: serine/threonine-protein kinase 38 isoform X4 [Mus musculus] 242409 4787 11.63666667 10.93333333 -0.089944542 Down 0.208845763 Tmem8b transmembrane protein 8B - - - - "gi|148670503|gb|EDL02450.1|/0/mCG19281, isoform CRA_b, partial [Mus musculus]" 67500 4478 5.066666667 4.646666667 -0.124840762 Down 0.208761142 Ccar1 cell division cycle and apoptosis regulator 1 K11978|1|7e-32|142|hgl:101709562|E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27] - - - - 72949 3514 5.143333333 4.723333333 -0.122898304 Down 0.208761142 Ccnt2 cyclin T2 K15188|1|0.0|1301|mmu:72949|cyclin T - - - gi|56550069|ref|NP_082675.1|/0/cyclin-T2 [Mus musculus] 100608 2039 7.956666667 8.51 0.096994971 Up 0.208751739 Noc4l NOC4 like K14771|1|0.0|992|mmu:100608|U3 small nucleolar RNA-associated protein 19 GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane - GO:0022613//ribonucleoprotein complex biogenesis gi|31981994|ref|NP_705798.2|/0/nucleolar complex protein 4 homolog [Mus musculus] 207596 7956.28 0.456666667 0.616666667 0.433349378 Up 0.208573094 Thsd4 "thrombospondin, type I, domain containing 4" K08624|1|5e-65|253|isc:IscW_ISCW021991|a disintegrin and metalloproteinase with thrombospondin motifs 9 [EC:3.4.24.-] GO:0043205//fibril GO:0004175//endopeptidase activity GO:0085029//extracellular matrix assembly gi|283135196|ref|NP_001035516.2|/0/thrombospondin type-1 domain-containing protein 4 isoform a precursor [Mus musculus] 232210 1422 3.873333333 3.523333333 -0.136634692 Down 0.208526082 Hmces "5-hydroxymethylcytosine (hmC) binding, ES cell specific" K05696|1|5e-38|161|ame:408900|tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48] - - - "gi|148666821|gb|EDK99237.1|/0/RIKEN cDNA 8430410A17, isoform CRA_b, partial [Mus musculus]" 102141 3067 3.516666667 3.866666667 0.136881806 Up 0.208526082 Snx25 sorting nexin 25 K17887|1|0.0|1496|mmu:102141|sorting nexin-25 GO:0043231//intracellular membrane-bounded organelle GO:0005543//phospholipid binding GO:0045184//establishment of protein localization;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway gi|258613896|ref|NP_997096.2|/0/sorting nexin-25 [Mus musculus] 70423 3605 3.503333333 3.85 0.136130182 Up 0.208526082 Tspan15 tetraspanin 15 K17297|1|3e-151|538|mmu:70423|tetraspanin-15 GO:0031224//intrinsic component of membrane - - gi|74182476|dbj|BAE42863.1|/2.04359e-159/unnamed protein product [Mus musculus] 70127 2230.92 3.883333333 3.53 -0.137627366 Down 0.208526082 Dpf3 "D4, zinc and double PHD fingers, family 3" K13196|1|3e-96|355|mcc:719503|zinc finger protein ubi-d4 - - - - 219072 1588 3.83 3.483333333 -0.136875856 Down 0.208526082 Haus4 "HAUS augmin-like complex, subunit 4" K16587|1|0.0|638|mmu:219072|HAUS augmin-like complex subunit 4;K16682|5|5e-149|530|cfa:480244|LIM domain-containing protein GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex - GO:0006461//protein complex assembly;GO:0031023//microtubule organizing center organization;GO:0000087//mitotic M phase gi|269954704|ref|NP_663437.2|/1.32885e-180/HAUS augmin-like complex subunit 4 [Mus musculus] 11306 5759 3.883333333 3.53 -0.137627366 Down 0.208526082 Abcb7 "ATP-binding cassette, sub-family B (MDR/TAP), member 7" "K05662|1|0.0|1374|mmu:11306|ATP-binding cassette, subfamily B (MDR/TAP), member 7" - - - "gi|148682136|gb|EDL14083.1|/0/mCG146161, partial [Mus musculus]" 76892 4434 3.466666667 3.813333333 0.137503524 Up 0.208526082 Rnft1 "ring finger protein, transmembrane 1" K10264|1|6e-73|279|cfa:611303|F-box and WD-40 domain protein 8;K12838|2|1e-24|118|api:100160417|poly(U)-binding-splicing factor PUF60;K11981|3|2e-07|61.6|ola:101163980|E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27];K14555|4|2e-06|58.5|cfr:102509202|U3 small nucleolar RNA-associated protein 13 GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding - gi|29747762|gb|AAH50796.1|/0/Rnft1 protein [Mus musculus] 216724 2657 17.61333333 18.58333333 0.077341338 Up 0.208507277 Rufy1 RUN and FYVE domain containing 1 K12482|1|0.0|1110|mmu:216724|RUN and FYVE domain-containing protein 1 GO:0005769//early endosome GO:0046914//transition metal ion binding;GO:0022892//substrate-specific transporter activity GO:0045184//establishment of protein localization;GO:0006897//endocytosis gi|27369788|ref|NP_766145.1|/0/RUN and FYVE domain-containing protein 1 [Mus musculus] 26433 3278 17.78333333 18.75 0.076364825 Up 0.208507277 Plod3 "procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3" K13646|1|0.0|1486|mmu:26433|lysyl hydroxylase/galactosyltransferase/glucosyltransferase [EC:1.14.11.4 2.4.1.50 2.4.1.66] GO:0005789//endoplasmic reticulum membrane "GO:0019842//vitamin binding;GO:0046914//transition metal ion binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0046527//glucosyltransferase activity;GO:0070815//peptidyl-lysine 5-dioxygenase activity" GO:0044710;GO:0009725//response to hormone;GO:0001885//endothelial cell development;GO:0022607//cellular component assembly;GO:0043009//chordate embryonic development;GO:0009887//organ morphogenesis;GO:0007399//nervous system development;GO:0033036;GO:0030198//extracellular matrix organization;GO:0050880//regulation of blood vessel size "gi|6755110|ref|NP_036092.1|/0/procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 precursor [Mus musculus]" 170737 5559.02 17.18333333 18.15333333 0.079224555 Up 0.208507277 Znrf1 zinc and ring finger 1 K10694|1|8e-47|192|pale:102898081|E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27] GO:0000323//lytic vacuole;GO:0008021//synaptic vesicle;GO:0000323//lytic vacuole;GO:0008021//synaptic vesicle;GO:0000323//lytic vacuole;GO:0008021//synaptic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046872//metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0006996//organelle organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0006996//organelle organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0006996//organelle organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0006996//organelle organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination "gi|148679554|gb|EDL11501.1|/1.51356e-151/zinc and ring finger 1, isoform CRA_a, partial [Mus musculus]" 212168 4348 5.816666667 6.286666667 0.11210264 Up 0.208497875 Zswim4 zinc finger SWIM-type containing 4 - - GO:0046914//transition metal ion binding - gi|26343619|dbj|BAC35466.1|/0/unnamed protein product [Mus musculus] 68128 1565 6.686666667 6.213333333 -0.105919746 Down 0.208497875 Fam120aos "family with sequence similarity 120A, opposite strand" - - - - - 70984 2653 2.886666667 2.58 -0.162033459 Down 0.208488473 4931406C07Rik RIKEN cDNA 4931406C07 gene K17266|1|2e-23|113|aqu:100636656|major vault protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0016787//hydrolase activity;GO:0046914//transition metal ion binding;GO:0016787//hydrolase activity;GO:0046914//transition metal ion binding;GO:0016787//hydrolase activity - "gi|148693071|gb|EDL25018.1|/0/RIKEN cDNA 4931406C07, isoform CRA_b, partial [Mus musculus]" 668212 6547 2.97 2.663333333 -0.157229929 Down 0.208488473 Efr3b EFR3 homolog B - - - - - 70478 2437.6 37.85666667 39.76333333 0.070891317 Up 0.208450863 Mipep mitochondrial intermediate peptidase K01410|1|0.0|1392|mmu:70478|mitochondrial intermediate peptidase [EC:3.4.24.59] GO:0044429;GO:0044429 GO:0004175//endopeptidase activity;GO:0043169//cation binding;GO:0004175//endopeptidase activity;GO:0043169//cation binding GO:0019538//protein metabolic process;GO:0019538//protein metabolic process gi|160333185|ref|NP_081712.2|/0/mitochondrial intermediate peptidase precursor [Mus musculus] 319582 1825 0.67 0.846666667 0.337632996 Up 0.208375644 6430573F11Rik RIKEN cDNA 6430573F11 gene K15444|1|5e-56|221|bfo:BRAFLDRAFT_90673|tRNA (uracil-5-)-methyltransferase TRM9 [EC:2.1.1.229];K10770|3|2e-39|166|tru:101067875|alkylated DNA repair protein alkB homolog 8 [EC:1.14.11.- 2.1.1.229] - GO:0016741 GO:0008152//metabolic process gi|40254307|ref|NP_795926.2|/0/probable tRNA methyltransferase 9-like protein [Mus musculus] 216080 1448 36.89666667 38.78333333 0.071946319 Up 0.208291023 Ube2d1 ubiquitin-conjugating enzyme E2D 1 K06689|1|4e-84|314|pbi:103061886|ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0032550;GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0001666//response to hypoxia;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle gi|744581725|ref|XP_010984128.1|/7.83162e-84/PREDICTED: ubiquitin-conjugating enzyme E2 D1 [Camelus dromedarius] 56367 1944.94 11.81 11.12333333 -0.086419779 Down 0.208253413 Scoc short coiled-coil protein K20316|1|2e-55|206|cge:100774622|short coiled-coil protein GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0010508//positive regulation of autophagy;GO:0010508//positive regulation of autophagy;GO:0010508//positive regulation of autophagy "gi|80475107|gb|AAI08408.1|/7.79217e-56/Scoc protein, partial [Mus musculus]" 67582 1933 11.61333333 10.92 -0.088809267 Down 0.208253413 Slc25a26 "solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26" "K15111|1|3e-136|488|mmu:67582|solute carrier family 25 (mitochondrial S-adenosylmethionine transporter), member 26" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0003333//amino acid transmembrane transport;GO:0015858//nucleoside transport gi|27754081|ref|NP_080531.2|/2.86995e-135/S-adenosylmethionine mitochondrial carrier protein [Mus musculus] 67622 1725 10.79666667 11.48666667 0.089374233 Up 0.208253413 Mxra7 matrix-remodelling associated 7 - - - - "gi|148702648|gb|EDL34595.1|/9.35129e-50/RIKEN cDNA 1810057P16, isoform CRA_b, partial [Mus musculus]" 225745 1004 10.75666667 11.45 0.090116521 Up 0.208253413 Haus1 "HAUS augmin-like complex, subunit 1" K16584|1|1e-118|428|mmu:225745|HAUS augmin-like complex subunit 1 GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex - GO:0006461//protein complex assembly;GO:0031023//microtubule organizing center organization;GO:0000087//mitotic M phase gi|22122593|ref|NP_666201.1|/1.06678e-117/HAUS augmin-like complex subunit 1 [Mus musculus] 56149 2025 10.91 11.6 0.088473704 Up 0.208253413 Grasp GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein K04465|1|1e-31|140|ccw:104683590|nuclear receptor subfamily 4 group A member 1;K13358|3|1e-07|61.2|ola:101168681|Na(+)/H(+) exchange regulatory cofactor NHE-RF2;K13365|4|1e-07|61.2|tru:101067452|Na(+)/H(+) exchange regulatory cofactor NHE-RF1 GO:0005737//cytoplasm;GO:0005635//nuclear envelope;GO:0016020//membrane GO:0019904//protein domain specific binding;GO:0031267//small GTPase binding GO:0007154//cell communication;GO:0015031//protein transport gi|7670470|dbj|BAA95086.1|/8.79493e-159/unnamed protein product [Mus musculus] 233210 6879 11.72 11.03 -0.087539779 Down 0.208253413 Prr12 proline rich 12 K11661|1|3e-92|343|acs:100567271|helicase SRCAP [EC:3.6.4.-];K13123|4|5e-67|260|mze:101475087|G patch domain-containing protein 1 - - - gi|153791304|ref|NP_778187.2|/0/proline-rich protein 12 [Mus musculus] 77428 2990 0.183333333 0.313333333 0.773229138 Up 0.208244011 9430083A17Rik RIKEN cDNA 9430083A17 gene - - - - "gi|68062078|ref|XP_673041.1|/7.75263e-16/hypothetical protein [Plasmodium berghei strain ANKA], partial [Plasmodium berghei ANKA]" 403178 3331 2.44 2.16 -0.175849835 Down 0.208225206 Plcxd1 "phosphatidylinositol-specific phospholipase C, X domain containing 1" - - GO:0042578//phosphoric ester hydrolase activity;GO:0042578//phosphoric ester hydrolase activity GO:0044238//primary metabolic process;GO:0044238//primary metabolic process gi|237649042|ref|NP_997162.2|/0/PI-PLC X domain-containing protein 1 isoform 1 [Mus musculus] 66492 2257 16.25 17.21333333 0.083086782 Up 0.208187596 Zmat2 "zinc finger, matrin type 2" K12848|1|2e-92|343|hgl:101715051|U4/U6.U5 tri-snRNP component SNU23 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - gi|970716772|ref|XP_006204598.2|/3.64406e-92/PREDICTED: zinc finger matrin-type protein 2 [Vicugna pacos] 74191 2541 0.373333333 0.526666667 0.496425826 Up 0.208187596 P2ry13 "purinergic receptor P2Y, G-protein coupled 13" "K08388|1|0.0|652|mmu:74191|purinergic receptor P2Y, G protein-coupled, 13" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0001608 GO:0035588 gi|240848558|ref|NP_083084.2|/0/P2Y purinoceptor 13 [Mus musculus] 240753 7330.77 18.28666667 17.32333333 -0.078075563 Down 0.208187596 Plekha6 "pleckstrin homology domain containing, family A member 6" K05076|1|1e-09|69.7|ptg:102949045|interleukin 13 receptor alpha-1;K18441|2|5e-08|64.3|nvi:100115603|cytohesin - GO:0008289//lipid binding - "gi|148707707|gb|EDL39654.1|/0/pleckstrin homology domain containing, family A member 6, isoform CRA_a, partial [Mus musculus]" 17846 818 40.35333333 38.48666667 -0.068329126 Down 0.208168792 Commd1 COMM domain containing 1 - GO:0031981//nuclear lumen;GO:0031461//cullin-RING ubiquitin ligase complex GO:0008200//ion channel inhibitor activity;GO:0042802//identical protein binding;GO:0043169//cation binding GO:0055080//cation homeostasis;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0016567//protein ubiquitination;GO:0061136//regulation of proteasomal protein catabolic process "gi|30109283|gb|AAH51210.1|/7.76241e-91/Commd1 protein, partial [Mus musculus]" 70397 1729.72 37.90333333 36.03 -0.073126077 Down 0.208168792 Tmem70 transmembrane protein 70 "K17966|1|7e-136|486|mmu:70397|transmembrane protein 70, mitochondrial" - - - "gi|117647263|ref|NP_081691.2|/5.54328e-135/transmembrane protein 70, mitochondrial isoform 1 [Mus musculus]" 338365 4386 0.423333333 0.28 -0.596367264 Down 0.208112377 Slc41a2 "solute carrier family 41, member 2" K15122|1|0.0|1059|mmu:338365|solute carrier family 41 GO:0031224//intrinsic component of membrane GO:0015075//ion transmembrane transporter activity GO:0006811//ion transport;GO:0044763 gi|28893565|ref|NP_796362.1|/0/solute carrier family 41 member 2 [Mus musculus] 225870 4176 0.793333333 0.983333333 0.309753381 Up 0.208102975 Rin1 Ras and Rab interactor 1 K17638|1|0.0|1172|mmu:225870|Ras and Rab interactor 1 GO:0043232 - GO:0007154//cell communication;GO:0016192//vesicle-mediated transport "gi|148701147|gb|EDL33094.1|/0/Ras and Rab interactor 1, isoform CRA_a [Mus musculus]" 99412 4475.72 38.99333333 37.14666667 -0.069994731 Down 0.208055963 Golga2 "golgi autoantigen, golgin subfamily a, 2" K20358|1|0.0|1402|mmu:99412|golgin subfamily A member 2 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body GO:0005515//protein binding;GO:0005515//protein binding GO:0051640//organelle localization;GO:0007409//axonogenesis;GO:0051640//organelle localization;GO:0007409//axonogenesis gi|124378042|ref|NP_598613.2|/0/golgin subfamily A member 2 isoform a [Mus musculus] 20909 1372 36.62333333 38.47333333 0.071095724 Up 0.208055963 Stx4a syntaxin 4A (placental) K13502|1|6e-152|539|mmu:20909|syntaxin 4 - - - - 26878 4578 0.2 0.093333333 -1.099535674 Down 0.208037158 B3galt2 "UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2" "K07820|1|0.0|893|mmu:26878|beta-1,3-galactosyltransferase 2 [EC:2.4.1.-]" GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0035250//UDP-galactosyltransferase activity GO:0006464//cellular protein modification process;GO:0009311//oligosaccharide metabolic process "gi|157266277|ref|NP_064409.3|/0/beta-1,3-galactosyltransferase 2 [Mus musculus]" 15194 13237 2.62 2.333333333 -0.16717439 Down 0.208008951 Htt huntingtin K04533|1|0.0|5663|mmu:15194|huntingtin - - - "gi|148705521|gb|EDL37468.1|/0/Huntington disease gene homolog, isoform CRA_b, partial [Mus musculus]" 29867 1181 2.606666667 2.316666667 -0.17015563 Down 0.208008951 Cabp1 calcium binding protein 1 K02183|1|3e-24|115|sko:100371257|calmodulin GO:0032991//macromolecular complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0012505//endomembrane system;GO:0043232;GO:0044459;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0012505//endomembrane system;GO:0043232;GO:0044459;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0044327//dendritic spine head;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0012505//endomembrane system;GO:0043232;GO:0044459;GO:0044444//cytoplasmic part GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0035256//G-protein coupled glutamate receptor binding;GO:0005048//signal sequence binding;GO:0030234//enzyme regulator activity;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0035256//G-protein coupled glutamate receptor binding;GO:0005048//signal sequence binding;GO:0030234//enzyme regulator activity;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0035256//G-protein coupled glutamate receptor binding;GO:0005048//signal sequence binding GO:1901020//negative regulation of calcium ion transmembrane transporter activity;GO:0050804//modulation of synaptic transmission;GO:0006606//protein import into nucleus;GO:0032502//developmental process;GO:0010644//cell communication by electrical coupling;GO:1901020//negative regulation of calcium ion transmembrane transporter activity;GO:0050804//modulation of synaptic transmission;GO:0006606//protein import into nucleus;GO:0032502//developmental process;GO:0010644//cell communication by electrical coupling;GO:1901020//negative regulation of calcium ion transmembrane transporter activity;GO:0050804//modulation of synaptic transmission;GO:0006606//protein import into nucleus;GO:0032502//developmental process;GO:0010644//cell communication by electrical coupling gi|894216294|ref|NP_001297641.1|/2.48991e-113/calcium-binding protein 1 isoform 1 [Mus musculus] 13057 764 35.98333333 37.82 0.071820526 Up 0.207990146 Cyba "cytochrome b-245, alpha polypeptide" "K08009|1|2e-68|260|mmu:13057|cytochrome b-245, alpha polypeptide" GO:0043005//neuron projection;GO:0044297//cell body;GO:0044432;GO:0005887//integral component of plasma membrane;GO:0043005//neuron projection;GO:0030666//endocytic vesicle membrane;GO:0044297//cell body;GO:0044432;GO:0005887//integral component of plasma membrane "GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0043169//cation binding;GO:0046906//tetrapyrrole binding;GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding" "GO:0051234//establishment of localization;GO:0010332//response to gamma radiation;GO:0009612//response to mechanical stimulus;GO:0042743//hydrogen peroxide metabolic process;GO:0014805//smooth muscle adaptation;GO:0006091//generation of precursor metabolites and energy;GO:0003083;GO:0008284//positive regulation of cell proliferation;GO:0034612//response to tumor necrosis factor;GO:0014070//response to organic cyclic compound;GO:0044710;GO:0043200//response to amino acid;GO:0043623//cellular protein complex assembly;GO:0009991//response to extracellular stimulus;GO:0006801//superoxide metabolic process;GO:0016049//cell growth;GO:0006952//defense response;GO:0001678//cellular glucose homeostasis;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0010332//response to gamma radiation;GO:0009612//response to mechanical stimulus;GO:0042743//hydrogen peroxide metabolic process;GO:0014805//smooth muscle adaptation;GO:0006996//organelle organization;GO:0003083;GO:0008284//positive regulation of cell proliferation;GO:0034612//response to tumor necrosis factor;GO:0014070//response to organic cyclic compound;GO:0044710;GO:0043200//response to amino acid;GO:0043623//cellular protein complex assembly;GO:0009991//response to extracellular stimulus;GO:0006801//superoxide metabolic process;GO:0016049//cell growth;GO:0006952//defense response;GO:0001678//cellular glucose homeostasis;GO:0044403//symbiosis, encompassing mutualism through parasitism" gi|160948588|ref|NP_031832.2|/4.3505e-90/cytochrome b-245 light chain isoform 1 [Mus musculus] 67134 1904 16.01666667 16.96666667 0.083129225 Up 0.207905525 Nop56 NOP56 ribonucleoprotein K14564|1|0.0|840|mmu:67134|nucleolar protein 56 GO:0030529//intracellular ribonucleoprotein complex GO:0003723//RNA binding - gi|126090932|ref|NP_077155.2|/0/nucleolar protein 56 [Mus musculus] 19704 4598 17.20666667 18.15666667 0.077531726 Up 0.207905525 Upf1 UPF1 regulator of nonsense transcripts homolog (yeast) K14326|1|0.0|2072|rno:684558|regulator of nonsense transcripts 1 [EC:3.6.4.-] GO:0044427;GO:0005681//spliceosomal complex;GO:0043234//protein complex;GO:0044427;GO:0035770//ribonucleoprotein granule;GO:0005681//spliceosomal complex;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0003724//RNA helicase activity;GO:0046914//transition metal ion binding;GO:0032550;GO:0003676//nucleic acid binding;GO:0003724//RNA helicase activity;GO:0046914//transition metal ion binding;GO:0032550;GO:0003676//nucleic acid binding GO:0007549//dosage compensation;GO:0006415//translational termination;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006259//DNA metabolic process;GO:0007549//dosage compensation;GO:0006415//translational termination;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006259//DNA metabolic process;GO:0006405//RNA export from nucleus gi|12836885|gb|AAK08652.1|AF182947_1/0/nonsense mRNA reducing factor 1 NORF1 [Mus musculus] 69787 1408 0.64 0.48 -0.415037499 Down 0.207905525 Anxa13 annexin A13 K17099|1|5e-176|619|mmu:69787|annexin A13 GO:0016020//membrane GO:0005543//phospholipid binding - gi|23956196|ref|NP_081487.1|/4.14479e-175/annexin A13 [Mus musculus] 70533 3111 16.31666667 17.26333333 0.081364699 Up 0.207905525 Btf3l4 basic transcription factor 3-like 4 K01527|1|3e-65|253|tup:102498200|nascent polypeptide-associated complex subunit beta - - - gi|568929722|ref|XP_006503448.1|/2.31014e-79/PREDICTED: transcription factor BTF3 homolog 4 isoform X2 [Mus musculus] 67861 1341 37.90666667 36.07333333 -0.071518858 Down 0.207896122 Akr1b10 "aldo-keto reductase family 1, member B10 (aldose reductase)" K00011|1|6e-173|609|mmu:67861|aldehyde reductase [EC:1.1.1.21] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005501//retinoid binding;GO:0043168//anion binding;GO:0008106//alcohol dehydrogenase (NADP+) activity GO:0030647;GO:0006066//alcohol metabolic process;GO:0001523//retinoid metabolic process;GO:0016107 "gi|71067102|ref|NP_765986.3|/5.25071e-172/aldo-keto reductase family 1, member B10 [Mus musculus]" 74150 2597 35.11333333 36.94 0.073164908 Up 0.207896122 Slc35f5 "solute carrier family 35, member F5" "K15289|1|0.0|922|mmu:74150|solute carrier family 35, member F5" GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization gi|148540182|ref|NP_083063.2|/0/solute carrier family 35 member F5 [Mus musculus] 72349 4204 39.85 38.02333333 -0.067694712 Down 0.207896122 Dusp3 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) K17614|1|7e-100|368|mmu:72349|dual specificity phosphatase 3 [EC:3.1.3.16 3.1.3.48] - - - - 14073 3816 0.01 0.083333333 3.058893689 Up 0.207717477 Faah fatty acid amide hydrolase K15528|1|0.0|957|mmu:14073|fatty acid amide hydrolase [EC:3.5.1.99] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0016298//lipase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0042802//identical protein binding;GO:0008289//lipid binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds" GO:0006631//fatty acid metabolic process gi|226443015|ref|NP_034303.3|/0/fatty-acid amide hydrolase 1 [Mus musculus] 171530 1002 0.01 0.08 3 Up 0.207717477 Ucn2 urocortin 2 K05257|1|3e-38|161|mmu:171530|urocortin 2/3 GO:0044421 GO:0051429 GO:0009888//tissue development;GO:0032277//negative regulation of gonadotropin secretion;GO:0010467//gene expression;GO:0032275//luteinizing hormone secretion;GO:0051384//response to glucocorticoid;GO:0046058//cAMP metabolic process;GO:0001666//response to hypoxia gi|254675176|ref|NP_659543.1|/2.43229e-37/urocortin-2 precursor [Mus musculus] 73129 938 0.01 0.08 3 Up 0.207717477 3110015C05Rik RIKEN cDNA 3110015C05 gene - - - - - 71995 3378 0.01 0.08 3 Up 0.207717477 Erv3 endogenous retroviral sequence 3 - - - - gi|261245004|ref|NP_001159678.1|/7.822e-121/endogenous retroviral sequence 3 precursor [Mus musculus] 58179 666 0.083333333 0.01 -3.058893689 Down 0.207717477 Klrc3 "killer cell lectin-like receptor subfamily C, member 3" K06541|1|2e-128|459|mmu:58179|killer cell lectin-like receptor subfamily C GO:0009986//cell surface GO:0005488//binding - "gi|10946714|ref|NP_067353.1|/1.50577e-127/killer cell lectin-like receptor subfamily C, member 3 [Mus musculus]" 381715 1167 0.01 0.08 3 Up 0.207717477 4930572O03Rik spermatogenesis associated glutamate (E)-rich protein pseudogene - - - - - 545645 811 0.08 0.01 -3 Down 0.207717477 Gm13283 predicted gene 13283 K05414|1|2e-37|157|cge:100763520|interferon alpha GO:0044421 GO:0005102//receptor binding GO:0007166//cell surface receptor signaling pathway;GO:0030098//lymphocyte differentiation;GO:0002252;GO:0007049//cell cycle;GO:0012501//programmed cell death gi|148224118|ref|NP_001079000.1|/9.62706e-102/uncharacterized protein LOC545645 precursor [Mus musculus] 11818 1202 0.01 0.083333333 3.058893689 Up 0.207717477 Apoh apolipoprotein H K17305|1|0.0|749|mmu:11818|beta-2-glycoprotein 1 GO:0034385;GO:0044464 GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0008289//lipid binding;GO:0060229//lipase activator activity GO:0001525//angiogenesis;GO:0051004;GO:0010594//regulation of endothelial cell migration;GO:0031638//zymogen activation;GO:0001935//endothelial cell proliferation;GO:0006639//acylglycerol metabolic process;GO:0042730//fibrinolysis;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0009887//organ morphogenesis;GO:0034196//acylglycerol transport;GO:0030194//positive regulation of blood coagulation;GO:0072376//protein activation cascade gi|160358825|ref|NP_038503.4|/0/beta-2-glycoprotein 1 precursor [Mus musculus] 246729 1318 0.01 0.08 3 Up 0.207717477 Oas1h 2'-5' oligoadenylate synthetase 1H K14216|1|1e-112|409|mmu:246730|2'-5'-oligoadenylate synthetase [EC:2.7.7.84] GO:0044424;GO:0044424 GO:0032550;GO:0003723//RNA binding;GO:0030234//enzyme regulator activity;GO:0070566//adenylyltransferase activity;GO:0032550;GO:0003723//RNA binding;GO:0030234//enzyme regulator activity;GO:0070566//adenylyltransferase activity GO:0008585//female gonad development;GO:0043086//negative regulation of catalytic activity;GO:0002252;GO:0008585//female gonad development;GO:0043086//negative regulation of catalytic activity;GO:0002252 gi|229576931|ref|NP_001153406.1|/2.39635e-137/2'-5' oligoadenylate synthetase 1H isoform 2 [Mus musculus] 75469 656 0.01 0.083333333 3.058893689 Up 0.207717477 Spata19 spermatogenesis associated 19 - - - - - 319823 1933 0.08 0.01 -3 Down 0.207717477 F630003A18Rik RIKEN cDNA F630003A18 gene K06531|1|2e-08|63.5|ola:101173334|poliovirus receptor-related protein 2;K06592|5|2e-07|60.5|ola:101160012|poliovirus receptor-related protein 3 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0005488//binding - gi|28892873|ref|NP_795984.1|/4.71009e-146/cell surface glycoprotein CD200 receptor 5 precursor [Mus musculus] 11542 2372 0.01 0.083333333 3.058893689 Up 0.207717477 Adora3 adenosine A3 receptor K04268|1|8e-172|606|mmu:11542|adenosine A3 receptor GO:0097060//synaptic membrane;GO:0016021//integral component of membrane GO:0004930//G-protein coupled receptor activity GO:0035588;GO:0051047//positive regulation of secretion;GO:0048243//norepinephrine secretion;GO:0009967//positive regulation of signal transduction;GO:0019722//calcium-mediated signaling;GO:0002441;GO:0033008 gi|110347604|ref|NP_033761.2|/7.1387e-171/adenosine receptor A3 [Mus musculus] 381272 648 0.083333333 0.01 -3.058893689 Down 0.207717477 A630095N17Rik RIKEN cDNA A630095N17 gene - - - - gi|340545548|ref|NP_001230019.1|/4.63238e-62/uncharacterized protein LOC381272 isoform 1 [Mus musculus] 574437 1636 0.01 0.083333333 3.058893689 Up 0.207717477 Xlr3b X-linked lymphocyte-regulated 3B K19528|1|1e-20|103|mmu:20962|synaptonemal complex protein 3 - - - gi|126032309|ref|NP_001075112.1|/3.25257e-121/X-linked lymphocyte-regulated protein 3B [Mus musculus] 107587 1710 0.01 0.08 3 Up 0.207717477 Osr2 odd-skipped related 2 K09215|1|6e-153|488|ecb:100055727|odd-skipped GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003677//DNA binding GO:0007369//gastrulation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001822//kidney development;GO:0043010//camera-type eye development;GO:0030326//embryonic limb morphogenesis;GO:0030282//bone mineralization;GO:0008284//positive regulation of cell proliferation;GO:0042471//ear morphogenesis;GO:0030154//cell differentiation;GO:0048704//embryonic skeletal system morphogenesis gi|859875901|ref|XP_012920244.1|/2.25308e-155/PREDICTED: protein odd-skipped-related 2 isoform X1 [Mustela putorius furo] 73721 662 0.01 0.083333333 3.058893689 Up 0.207717477 1110017D15Rik RIKEN cDNA 1110017D15 gene K18634|1|3e-52|114|ptg:102967373|spermatid-specific manchette-related protein 1 GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0006461//protein complex assembly;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0006461//protein complex assembly;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0006461//protein complex assembly;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0006461//protein complex assembly;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0006461//protein complex assembly;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0006461//protein complex assembly;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0006461//protein complex assembly;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0006461//protein complex assembly;GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|359339012|ref|NP_001240706.1|/0/spermatid-specific manchette-related protein 1 isoform 3 [Mus musculus] 22326 2719 0.01 0.08 3 Up 0.207717477 Vax1 ventral anterior homeobox 1 K09318|1|4e-131|471|mmu:22326|homeobox protein ventral anterior - - - - 627860 684 0.01 0.08 3 Up 0.207717477 Cyp2d37-ps "cytochrome P450, family 2, subfamily d, polypeptide 37, pseudogene" "K07414|1|1e-44|153|mmu:76279|cytochrome P450, family 2, subfamily D [EC:1.14.14.1]" GO:0043231//intracellular membrane-bounded organelle "GO:0005488//binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0004497//monooxygenase activity" GO:0006629//lipid metabolic process;GO:0055114//oxidation-reduction process;GO:0042221//response to chemical;GO:1901360//organic cyclic compound metabolic process;GO:0065007//biological regulation;GO:0006725//cellular aromatic compound metabolic process;GO:0017144//drug metabolic process;GO:0009820//alkaloid metabolic process gi|148672543|gb|EDL04490.1|/9.14674e-46/mCG4191 [Mus musculus] 320315 667 0.01 0.083333333 3.058893689 Up 0.207717477 A330048O09Rik RIKEN cDNA A330048O09 gene - - - - - 100040572 733 0.08 0.01 -3 Down 0.207717477 Gm2848 predicted gene 2848 - - - - - 14103 1889 0.01 0.08 3 Up 0.207717477 Fasl "Fas ligand (TNF superfamily, member 6)" K04389|1|2e-145|518|mmu:14103|tumor necrosis factor ligand superfamily member 6 - - - - 68771 667 0.08 0.01 -3 Down 0.207717477 1110058D11Rik RIKEN cDNA 1110058D11 gene - - - - - 20299 1815 0.01 0.083333333 3.058893689 Up 0.207717477 Ccl22 chemokine (C-C motif) ligand 22 "K05514|1|6e-33|144|mmu:20299|C-C motif chemokine, other" GO:0044421 GO:0005125//cytokine activity GO:0006952//defense response;GO:0002376//immune system process;GO:0042221//response to chemical gi|5911365|gb|AAD55763.1|AF163476_1/5.51726e-32/macrophage-derived chemokine [Mus musculus] 545648 811 0.08 0.01 -3 Down 0.207717477 Gm13272 predicted gene 13272 K05414|1|3e-38|160|cge:100763520|interferon alpha GO:0044421 GO:0005102//receptor binding GO:0007166//cell surface receptor signaling pathway;GO:0030098//lymphocyte differentiation;GO:0002252;GO:0007049//cell cycle;GO:0012501//programmed cell death gi|239050335|ref|NP_001155080.1|/7.37118e-102/interferon zeta-like precursor [Mus musculus] 12796 599 0.01 0.08 3 Up 0.207717477 Camp cathelicidin antimicrobial peptide K13916|1|2e-68|260|mmu:12796|cathelicidin antimicrobial peptide - - - - 379043 1274 0.083333333 0.01 -3.058893689 Down 0.207717477 Raet1e retinoic acid early transcript 1E K07987|1|4e-123|443|mmu:379043|retinoic acid early transcript 1 GO:0046658//anchored component of plasma membrane;GO:0009986//cell surface GO:0005102//receptor binding GO:0032496//response to lipopolysaccharide;GO:0030101//natural killer cell activation;GO:0006809//nitric oxide biosynthetic process;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0001819//positive regulation of cytokine production;GO:0002696//positive regulation of leukocyte activation;GO:0043330//response to exogenous dsRNA gi|38016148|ref|NP_937836.1|/3.53675e-122/retinoic acid early-inducible protein 1-epsilon precursor [Mus musculus] 72104 657 0.083333333 0.01 -3.058893689 Down 0.207717477 2010106C02Rik RIKEN cDNA 2010106C02 gene - - - - - 78547 696 0.08 0.01 -3 Down 0.207717477 E130304I02Rik RIKEN cDNA E130304I02 gene - - - - gi|148671057|gb|EDL03004.1|/2.27587e-36/mCG21289 [Mus musculus] 17173 1612 0.01 0.083333333 3.058893689 Up 0.207717477 Ascl2 achaete-scute family bHLH transcription factor 2 K09067|1|3e-94|348|mmu:17173|achaete-scute complex protein - - - - 73712 661 0.01 0.083333333 3.058893689 Up 0.207717477 Dmkn dermokine - GO:0044421 - GO:0048869//cellular developmental process gi|261244936|ref|NP_001159645.1|/1.85172e-111/dermokine isoform c precursor [Mus musculus] 78625 2455 0.083333333 0.01 -3.058893689 Down 0.207717477 1700061G19Rik RIKEN cDNA 1700061G19 gene K15013|1|0.0|1351|mmu:78625|long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3] - - - "gi|148706264|gb|EDL38211.1|/0/mCG127436, isoform CRA_d, partial [Mus musculus]" 15208 1273 0.083333333 0.01 -3.058893689 Down 0.207717477 Hes5 hairy and enhancer of split 5 (Drosophila) K06055|1|2e-65|251|mcf:102143983|hairy and enhancer of split 5 GO:0031981//nuclear lumen "GO:0043566//structure-specific DNA binding;GO:0005515//protein binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding" GO:0021700//developmental maturation;GO:0045632;GO:0008284//positive regulation of cell proliferation;GO:0001501//skeletal system development;GO:0021879//forebrain neuron differentiation;GO:0014003//oligodendrocyte development;GO:0042552//myelination;GO:0045686//negative regulation of glial cell differentiation;GO:0001654//eye development;GO:0030509//BMP signaling pathway;GO:0007219//Notch signaling pathway;GO:0022610;GO:0002328//pro-B cell differentiation;GO:0009912//auditory receptor cell fate commitment;GO:0065003;GO:0072078//nephron tubule morphogenesis;GO:0019827//stem cell population maintenance;GO:0042503//tyrosine phosphorylation of Stat3 protein gi|568930612|ref|XP_006538625.1|/1.66591e-71/PREDICTED: transcription factor HES-5 isoform X1 [Mus musculus] 76419 658 0.01 0.083333333 3.058893689 Up 0.207717477 Smkr-ps "smal lysine rich protein 1, pseudogene" K11136|1|1e-07|58.9|myb:102260209|regulator of telomere elongation helicase 1 [EC:3.6.4.12] - - - - 16641 1993 0.08 0.01 -3 Down 0.207717477 Klrc1 "killer cell lectin-like receptor subfamily C, member 1" K06541|1|1e-137|492|mmu:16641|killer cell lectin-like receptor subfamily C GO:0009986//cell surface;GO:0009986//cell surface - - gi|209862943|ref|NP_001129540.1|/1.21226e-136/NKG2-A/NKG2-B type II integral membrane protein isoform 1 [Mus musculus] 70928 1781 0.01 0.083333333 3.058893689 Up 0.207717477 Trim69 tripartite motif-containing 69 K12034|1|0.0|993|mmu:70928|tripartite motif-containing protein 69 [EC:2.3.2.27] GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0012501//programmed cell death gi|160333353|ref|NP_536771.2|/0/E3 ubiquitin-protein ligase TRIM69 [Mus musculus] 23934 1300 0.083333333 0.01 -3.058893689 Down 0.207717477 Ly6h "lymphocyte antigen 6 complex, locus H" K06846|1|2e-62|242|ngi:103743595|lymphocyte antigen 6 complex locus protein D/E/G6/H GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0048731//system development;GO:0009653//anatomical structure morphogenesis;GO:0048731//system development;GO:0009653//anatomical structure morphogenesis;GO:0048731//system development;GO:0009653//anatomical structure morphogenesis gi|12861758|dbj|BAB32273.1|/5.77536e-82/unnamed protein product [Mus musculus] 100041379 4003 0.08 0.01 -3 Down 0.207717477 Gm13242 zinc finger protein 980 K09228|1|0.0|1436|mmu:102632968|KRAB domain-containing zinc finger protein - - - gi|755510436|ref|XP_011248678.1|/0/PREDICTED: zinc finger protein 665-like [Mus musculus] 319981 1239 0.083333333 0.01 -3.058893689 Down 0.207717477 C530044C16Rik RIKEN cDNA C530044C16 gene - - - - - 74953 1237 0.01 0.083333333 3.058893689 Up 0.207717477 4930483K19Rik RIKEN cDNA 4930483K19 gene K01852|1|2e-22|108|mmu:16987|lanosterol synthase [EC:5.4.99.7] - - - - 234836 656 0.01 0.083333333 3.058893689 Up 0.207717477 Il17c interleukin 17C K05491|1|6e-104|378|mmu:234836|interleukin 17C GO:0044421 - GO:0001819//positive regulation of cytokine production;GO:0030851//granulocyte differentiation gi|164420675|ref|NP_665833.3|/4.2065e-103/interleukin-17C precursor [Mus musculus] 67717 1353 0.08 0.01 -3 Down 0.207717477 Lipf "lipase, gastric" K14452|1|0.0|823|mmu:67717|gastric triacylglycerol lipase [EC:3.1.1.3] - GO:0052689//carboxylic ester hydrolase activity GO:0006629//lipid metabolic process gi|755563571|ref|XP_011245624.1|/0/PREDICTED: gastric triacylglycerol lipase isoform X1 [Mus musculus] 100040843 1914 0.083333333 0.01 -3.058893689 Down 0.207717477 Cyp4a32 "cytochrome P450, family 4, subfamily a, polypeptide 32" K07425|1|0.0|1003|mmu:100040843|alkane 1-monooxygenase [EC:1.14.15.3] GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0044459 "GO:0046914//transition metal ion binding;GO:0016713;GO:0046906//tetrapyrrole binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0008391//arachidonic acid monooxygenase activity" GO:0051791//medium-chain fatty acid metabolic process;GO:0032303;GO:0055065//metal ion homeostasis;GO:0036100;GO:0001977;GO:0019369//arachidonic acid metabolic process;GO:0044767//single-organism developmental process "gi|154146206|ref|NP_001093651.1|/0/cytochrome P450, family 4, subfamily a, polypeptide 32 [Mus musculus]" 71934 2299 0.213333333 0.1 -1.093109404 Down 0.207708075 Car13 carbonic anhydrase 13 K01672|1|2e-153|545|mmu:71934|carbonic anhydrase [EC:4.2.1.1] - GO:0003824//catalytic activity;GO:0046914//transition metal ion binding GO:0044237//cellular metabolic process gi|13374567|ref|NP_078771.1|/1.43935e-152/carbonic anhydrase 13 [Mus musculus] 226153 3515 11.19666667 11.88 0.085465541 Up 0.207670465 Peo1 progressive external ophthalmoplegia 1 (human) K17680|1|0.0|1327|mmu:226153|twinkle protein [EC:3.6.4.12] GO:0005759//mitochondrial matrix GO:0003678//DNA helicase activity;GO:0032550;GO:0019899//enzyme binding;GO:0043566//structure-specific DNA binding GO:0000959//mitochondrial RNA metabolic process;GO:0051259//protein oligomerization;GO:0006261//DNA-dependent DNA replication "gi|24962647|ref|NP_722491.2|/0/twinkle protein, mitochondrial [Mus musculus]" 69860 2469 10.73666667 11.42 0.089016491 Up 0.207670465 Eif1ad eukaryotic translation initiation factor 1A domain containing K15025|1|3e-75|286|mmu:69860|probable RNA-binding protein EIF1AD GO:0043231//intracellular membrane-bounded organelle "GO:0008135//translation factor activity, RNA binding" GO:0006412//translation gi|58037183|ref|NP_081512.1|/2.23297e-74/probable RNA-binding protein EIF1AD [Mus musculus] 13018 3848 11.10333333 10.42 -0.091637576 Down 0.207670465 Ctcf CCCTC-binding factor K09228|1|8e-64|248|cge:103159248|KRAB domain-containing zinc finger protein GO:0031981//nuclear lumen;GO:0044427 GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0031490//chromatin DNA binding "GO:0007549//dosage compensation;GO:0006351//transcription, DNA-templated;GO:0007063//regulation of sister chromatid cohesion;GO:0065009;GO:0016571//histone methylation;GO:0006305;GO:0034728//nucleosome organization;GO:0016573//histone acetylation" "gi|148679349|gb|EDL11296.1|/0/CCCTC-binding factor, isoform CRA_d [Mus musculus]" 629557 1466 0.363333333 0.51 0.489203518 Up 0.207642258 Gm6981 glyceraldehyde-3-phosphate dehydrogenase pseudogene K00134|1|6e-170|599|mmu:14433|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] - - - - 19652 1356.31 37.54 35.74 -0.070889016 Down 0.207614051 Rbm3 RNA binding motif protein 3 K13186|1|2e-39|165|pale:102889767|RNA-binding protein 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0044391//ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0044391//ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0044391//ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0044391//ribosomal subunit;GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0044391//ribosomal subunit GO:0003676//nucleic acid binding;GO:0043021//ribonucleoprotein complex binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0043021//ribonucleoprotein complex binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0043021//ribonucleoprotein complex binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0043021//ribonucleoprotein complex binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0043021//ribonucleoprotein complex binding;GO:0036094//small molecule binding GO:0006412//translation;GO:0006950//response to stress;GO:0035195//gene silencing by miRNA;GO:0006412//translation;GO:0006950//response to stress;GO:0035195//gene silencing by miRNA;GO:0006412//translation;GO:0006950//response to stress;GO:0035195//gene silencing by miRNA;GO:0006412//translation;GO:0006950//response to stress;GO:0035195//gene silencing by miRNA;GO:0006412//translation;GO:0006950//response to stress;GO:0035195//gene silencing by miRNA "gi|148702008|gb|EDL33955.1|/2.38725e-47/mCG116386, isoform CRA_e, partial [Mus musculus]" 18301 1040.41 38.17666667 39.98 0.06658733 Up 0.207614051 Fxyd5 FXYD domain-containing ion transport regulator 5 K13362|1|4e-87|323|mmu:18301|FXYD domain-containing ion transport regulator 5 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0050839//cell adhesion molecule binding;GO:0015075//ion transmembrane transporter activity;GO:0008092//cytoskeletal protein binding;GO:0050839//cell adhesion molecule binding;GO:0015075//ion transmembrane transporter activity;GO:0008092//cytoskeletal protein binding;GO:0050839//cell adhesion molecule binding;GO:0015075//ion transmembrane transporter activity;GO:0008092//cytoskeletal protein binding;GO:0050839//cell adhesion molecule binding;GO:0015075//ion transmembrane transporter activity;GO:0008092//cytoskeletal protein binding GO:0044765//single-organism transport;GO:0044765//single-organism transport;GO:0044765//single-organism transport;GO:0044765//single-organism transport gi|6679168|ref|NP_032787.1|/2.93678e-86/FXYD domain-containing ion transport regulator 5 isoform a precursor [Mus musculus] 66272 985.91 16.89333333 15.95666667 -0.082294718 Down 0.207604649 Cox16 cytochrome c oxidase assembly protein 16 K18182|1|4e-41|172|rno:100302447|cytochrome c oxidase assembly protein subunit 16 GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane;GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane;GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane;GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane - - "gi|625253043|ref|XP_007617861.1|/4.22927e-32/PREDICTED: cytochrome c oxidase assembly protein COX16 homolog, mitochondrial isoform X2 [Cricetulus griseus]" 213539 1815 33.80333333 35.58333333 0.074036147 Up 0.207426003 Bag2 BCL2-associated athanogene 2 K09556|1|8e-111|403|mmu:213539|BCL2-associated athanogene 2 - GO:0005515//protein binding GO:0044267//cellular protein metabolic process gi|21703784|ref|NP_663367.1|/6.57536e-110/BAG family molecular chaperone regulator 2 [Mus musculus] 235497 2192 6.29 5.833333333 -0.108739501 Down 0.207378991 Leo1 "Leo1, Paf1/RNA polymerase II complex component" K15177|1|0.0|1036|mmu:235497|RNA polymerase-associated protein LEO1 - - - - 99712 2814 5.876666667 6.336666667 0.108726057 Up 0.207378991 Cept1 choline/ethanolaminephosphotransferase 1 K13644|1|0.0|840|mmu:99712|choline/ethanolamine phosphotransferase [EC:2.7.8.1 2.7.8.2] GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0043169//cation binding;GO:0017169//CDP-alcohol phosphatidyltransferase activity;GO:0043169//cation binding;GO:0017169//CDP-alcohol phosphatidyltransferase activity GO:0006656//phosphatidylcholine biosynthetic process;GO:0046337//phosphatidylethanolamine metabolic process;GO:0006644//phospholipid metabolic process;GO:0046165 gi|965838748|ref|XP_011990142.2|/0/PREDICTED: choline/ethanolaminephosphotransferase 1 isoform X4 [Ovis aries musimon] 58248 1889 5.91 6.366666667 0.107380102 Up 0.207378991 1700123O20Rik RIKEN cDNA 1700123O20 gene K12875|1|1e-52|210|mmu:56215|apoptotic chromatin condensation inducer in the nucleus GO:0043231//intracellular membrane-bounded organelle - - gi|584064989|ref|XP_006776844.1|/2.40604e-78/PREDICTED: uncharacterized protein C14orf119 homolog isoform X1 [Myotis davidii] 67116 1827.57 36.29 38.05666667 0.068577147 Up 0.207350784 Cuedc2 CUE domain containing 2 K10281|1|2e-29|132|umr:103659034|F-box and leucine-rich repeat protein 15 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - - "gi|148710050|gb|EDL41996.1|/6.79762e-163/CUE domain containing 2, isoform CRA_g, partial [Mus musculus]" 16578 2744 0.133333333 0.253333333 0.925999419 Up 0.207303772 Kif9 kinesin family member 9 K10397|1|0.0|1392|mmu:16578|kinesin family member 6/9 - - - gi|568963465|ref|XP_006512004.1|/0/PREDICTED: kinesin-like protein KIF9 isoform X2 [Mus musculus] 67608 4426 36.09333333 37.85666667 0.068814998 Up 0.20725676 Narf nuclear prelamin A recognition factor - GO:0005882//intermediate filament;GO:0034399//nuclear periphery GO:0005515//protein binding - gi|163954939|ref|NP_080548.3|/0/nuclear prelamin A recognition factor [Mus musculus] 64340 4190 7.603333333 7.076666667 -0.103562075 Down 0.20725676 Dhx38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 K12815|1|0.0|2026|mmu:64340|pre-mRNA-splicing factor ATP-dependent RNA helicase DHX38/PRP16 [EC:3.6.4.13] GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen "GO:0032550;GO:0042623//ATPase activity, coupled" GO:0000377;GO:0006405//RNA export from nucleus;GO:0006397//mRNA processing;GO:0006366//transcription from RNA polymerase II promoter gi|30410010|ref|NP_848467.1|/0/pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 [Mus musculus] 12793 1484 35.76333333 37.51333333 0.068922253 Up 0.207219151 Cnih1 cornichon family AMPA receptor auxiliary protein 1 K20368|1|2e-63|245|xla:447072|protein cornichon - - - - 70604 1851 2.166666667 1.903333333 -0.186948973 Down 0.207190944 Dnajb14 DnaJ heat shock protein family (Hsp40) member B14 K09520|1|0.0|689|mmu:70604|DnaJ homolog subfamily B member 14 - - - - 100503040 2530 1.823333333 2.083333333 0.192315357 Up 0.207190944 Gm19522 "predicted gene, 19522" - - - - - 225207 6152 2.066666667 1.806666667 -0.193975364 Down 0.207190944 Zfp521 zinc finger protein 521 K09228|1|1e-92|345|myb:102259112|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding "GO:0048869//cellular developmental process;GO:0006351//transcription, DNA-templated" gi|47847416|dbj|BAD21380.1|/0/mFLJ00107 protein [Mus musculus] 210530 2248 1.803333333 2.06 0.191978244 Up 0.207190944 P3h2 prolyl 3-hydroxylase 2 K08134|1|0.0|644|lcm:102356877|leucine proline-enriched proteoglycan (leprecan) GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix "GO:0019842//vitamin binding;GO:0046914//transition metal ion binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0019798//procollagen-proline dioxygenase activity" GO:0044259//multicellular organismal macromolecule metabolic process;GO:0018208//peptidyl-proline modification;GO:0008283//cell proliferation gi|27734076|ref|NP_775555.1|/0/prolyl 3-hydroxylase 2 precursor [Mus musculus] 52589 3483.84 1.833333333 2.096666667 0.193628398 Up 0.207190944 Ncald neurocalcin delta K19695|1|3e-107|392|gja:107124651|neurocalcin delta GO:0012510//trans-Golgi network transport vesicle membrane;GO:0012510//trans-Golgi network transport vesicle membrane;GO:0012510//trans-Golgi network transport vesicle membrane;GO:0012510//trans-Golgi network transport vesicle membrane GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0046872//metal ion binding;GO:0015631//tubulin binding GO:0006810//transport;GO:0007267//cell-cell signaling;GO:0006810//transport;GO:0007267//cell-cell signaling;GO:0006810//transport;GO:0007267//cell-cell signaling;GO:0006810//transport;GO:0007267//cell-cell signaling gi|27806017|ref|NP_776823.1|/2.51121e-106/neurocalcin-delta [Bos taurus] 54609 3343 11.56666667 10.89333333 -0.086527679 Down 0.207181541 Ubqln2 ubiquilin 2 K04523|1|0.0|800|mmu:54609|ubiquilin GO:0044424;GO:0016020//membrane - - gi|34328236|ref|NP_061268.2|/0/ubiquilin-2 [Mus musculus] 100465 2882 2.91 3.23 0.150515012 Up 0.207162736 Mob3c MOB kinase activator 3C K06685|1|4e-76|289|cel:CELE_T12B3.4|MOB kinase activator 1 - "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0043169//cation binding" GO:0006796//phosphate-containing compound metabolic process "gi|71119339|gb|AAH99740.1|/2.61396e-162/Mobkl2c protein, partial [Mus musculus]" 11486 1701 0.7 0.88 0.330148602 Up 0.207134529 Ada adenosine deaminase K01488|1|0.0|688|mmu:11486|adenosine deaminase [EC:3.5.4.4] - - - gi|6680636|ref|NP_031424.1|/0/adenosine deaminase [Mus musculus] 22174 4005 0.676666667 0.853333333 0.334664083 Up 0.207134529 Tyro3 TYRO3 protein tyrosine kinase 3 K05116|1|0.0|1630|mmu:22174|TYRO3 protein tyrosine kinase 3 [EC:2.7.10.1] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0046983//protein dimerization activity;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0046983//protein dimerization activity GO:0031348//negative regulation of defense response;GO:0006909//phagocytosis;GO:0030168//platelet activation;GO:0043066//negative regulation of apoptotic process;GO:0002224//toll-like receptor signaling pathway;GO:0022610;GO:0002695//negative regulation of leukocyte activation;GO:0006468//protein phosphorylation;GO:0019725//cellular homeostasis;GO:0000904//cell morphogenesis involved in differentiation;GO:0030540//female genitalia development;GO:0048232//male gamete generation;GO:0006954//inflammatory response;GO:0030098//lymphocyte differentiation;GO:0016477//cell migration;GO:0046903//secretion;GO:0031348//negative regulation of defense response;GO:0006909//phagocytosis;GO:0030168//platelet activation;GO:0043066//negative regulation of apoptotic process;GO:0002224//toll-like receptor signaling pathway;GO:0022610;GO:0002695//negative regulation of leukocyte activation;GO:0006468//protein phosphorylation;GO:0019725//cellular homeostasis;GO:0000904//cell morphogenesis involved in differentiation;GO:0030540//female genitalia development;GO:0048232//male gamete generation;GO:0006954//inflammatory response;GO:0030098//lymphocyte differentiation;GO:0016477//cell migration;GO:0046903//secretion gi|595763335|ref|NP_001277729.1|/0/tyrosine-protein kinase receptor TYRO3 isoform B [Mus musculus] 241770 832 0.983333333 0.796666667 -0.303704336 Down 0.207134529 Rims4 regulating synaptic membrane exocytosis 4 K15299|1|1e-144|514|mmu:241770|regulating synaptic membrane exocytosis protein 4 GO:0016020//membrane GO:0005515//protein binding GO:0016079//synaptic vesicle exocytosis;GO:0006873//cellular ion homeostasis gi|33942097|ref|NP_898844.1|/1.06044e-143/regulating synaptic membrane exocytosis protein 4 [Mus musculus] 16520 2167 0.87 0.69 -0.334419039 Down 0.207134529 Kcnj4 "potassium inwardly-rectifying channel, subfamily J, member 4" K04998|1|0.0|729|mmu:16520|potassium inwardly-rectifying channel subfamily J member 4 GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044459;GO:0012506//vesicle membrane GO:0005249//voltage-gated potassium channel activity;GO:0019904//protein domain specific binding GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|158711668|ref|NP_032453.3|/0/inward rectifier potassium channel 4 [Mus musculus] 16533 4188 1.036666667 0.843333333 -0.297777195 Down 0.207134529 Kcnmb1 "potassium large conductance calcium-activated channel, subfamily M, beta member 1" K04937|1|5e-107|392|mmu:16533|potassium large conductance calcium-activated channel subfamily M beta member 1 GO:0005887//integral component of plasma membrane GO:0005227//calcium activated cation channel activity;GO:0016247//channel regulator activity GO:0030001//metal ion transport;GO:0010038//response to metal ion gi|31981659|ref|NP_112446.2|/4.04348e-106/calcium-activated potassium channel subunit beta-1 [Mus musculus] 77766 6755 1.726666667 1.976666667 0.195080007 Up 0.207125127 Elp4 elongator acetyltransferase complex subunit 4 K11375|1|0.0|781|mmu:77766|elongator complex protein 4 - - - - 70797 6330.71 1.936666667 1.69 -0.196552416 Down 0.207125127 Ankib1 ankyrin repeat and IBR domain containing 1 K11967|1|0.0|1164|mmu:70797|ankyrin repeat and IBR domain-containing protein 1 - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - gi|575501653|ref|NP_001276456.1|/0/ankyrin repeat and IBR domain-containing protein 1 isoform 1 [Mus musculus] 234730 3874 1.993333333 1.74 -0.196095678 Down 0.207125127 Fuk fucokinase K05305|1|0.0|1172|mmu:234730|fucokinase [EC:2.7.1.52] GO:0044424 GO:0016301//kinase activity;GO:0032550;GO:0016301//kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006796//phosphate-containing compound metabolic process "gi|148679529|gb|EDL11476.1|/0/fucokinase, isoform CRA_b, partial [Mus musculus]" 66254 2545 1.7 1.95 0.197939378 Up 0.207125127 Dimt1 DIM1 dimethyladenosine transferase 1-like (S. cerevisiae) K14191|1|4e-155|551|mmu:66254|18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase [EC:2.1.1.183] GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0008988//rRNA (adenine-N6-)-methyltransferase activity GO:0000154//rRNA modification gi|564335149|ref|XP_006231964.1|/5.39422e-156/PREDICTED: probable dimethyladenosine transferase isoform X2 [Rattus norvegicus] 12227 3083 16.85333333 15.93333333 -0.080985845 Down 0.207021701 Btg2 "B cell translocation gene 2, anti-proliferative" K14443|1|3e-86|322|cge:100766229|protein Tob/BTG - GO:0005488//binding GO:0009605//response to external stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0007612//learning;GO:0021766//hippocampus development;GO:0008213;GO:0008285//negative regulation of cell proliferation;GO:0003002//regionalization;GO:0021953//central nervous system neuron differentiation;GO:0030030//cell projection organization;GO:0007519//skeletal muscle tissue development;GO:0009628//response to abiotic stimulus;GO:0033554//cellular response to stress;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0009725//response to hormone gi|913492365|ref|XP_005348427.2|/4.90589e-94/PREDICTED: protein BTG2 [Microtus ochrogaster] 97827 3323 4.09 4.463333333 0.126020712 Up 0.206955884 Exd2 exonuclease 3'-5' domain containing 2 K10900|1|7e-13|79.3|dre:569495|werner syndrome ATP-dependent helicase [EC:3.6.4.12] GO:0044464 GO:0097159//organic cyclic compound binding;GO:0004527//exonuclease activity GO:0006725//cellular aromatic compound metabolic process gi|237681098|ref|NP_598559.2|/0/exonuclease 3'-5' domain-containing protein 2 [Mus musculus] 546071 5334 4.096666667 4.47 0.125824322 Up 0.206955884 Mast3 microtubule associated serine/threonine kinase 3 K08789|1|0.0|2025|mmu:546071|microtubule-associated serine/threonine kinase [EC:2.7.11.1] - - - gi|256017165|ref|NP_955012.2|/0/microtubule-associated serine/threonine-protein kinase 3 [Mus musculus] 28040 2238 3.896666667 4.263333333 0.129741334 Up 0.206955884 D6Wsu163e "DNA segment, Chr 6, Wayne State University 163, expressed" - - - - - 319974 6060 4.376666667 4.003333333 -0.128630765 Down 0.206955884 Auts2 autism susceptibility candidate 2 - - - - gi|124486586|ref|NP_796021.2|/0/autism susceptibility gene 2 protein [Mus musculus] 56869 2747 0.226666667 0.113333333 -1 Down 0.206946482 Zfp109 zinc finger protein 109 K09228|1|0.0|1387|mmu:56869|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|9931982|ref|NP_064658.1|/0/zinc finger protein 109 [Mus musculus] 71100 922 0.226666667 0.113333333 -1 Down 0.206946482 4933413L06Rik RIKEN cDNA 4933413L06 gene - - - - - 64214 1859 0.213333333 0.103333333 -1.04580369 Down 0.206946482 Rgs18 regulator of G-protein signaling 18 K16449|1|5e-131|470|mmu:64214|regulator of G-protein signaling - - - gi|12738845|ref|NP_075019.1|/4.524e-130/regulator of G-protein signaling 18 [Mus musculus] 60534 2723 1.396666667 1.623333333 0.216971528 Up 0.206918274 Fancg "Fanconi anemia, complementation group G" K10894|1|0.0|982|mmu:60534|fanconi anemia group G protein GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex - GO:0006996//organelle organization;GO:0006259//DNA metabolic process;GO:0009628//response to abiotic stimulus;GO:0033554//cellular response to stress;GO:0007281//germ cell development;GO:0006996//organelle organization;GO:0006259//DNA metabolic process;GO:0009628//response to abiotic stimulus;GO:0033554//cellular response to stress;GO:0007281//germ cell development "gi|148670551|gb|EDL02498.1|/0/Fanconi anemia, complementation group G, isoform CRA_b, partial [Mus musculus]" 57814 2487 1.643333333 1.41 -0.220929983 Down 0.206918274 Kcne4 "potassium voltage-gated channel, Isk-related subfamily, gene 4" K04898|1|2e-73|280|cge:100773476|potassium voltage-gated channel Isk-related subfamily E member 4 GO:0005887//integral component of plasma membrane GO:0005267//potassium channel activity GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|589917750|ref|XP_006972183.1|/1.22381e-74/PREDICTED: potassium voltage-gated channel subfamily E member 4 [Peromyscus maniculatus bairdii] 68999 2802 1.683333333 1.45 -0.215267987 Down 0.206918274 Anapc10 anaphase promoting complex subunit 10 K03357|1|6e-106|388|myb:102242432|anaphase-promoting complex subunit 10 GO:0031981//nuclear lumen;GO:0000152//nuclear ubiquitin ligase complex;GO:0044444//cytoplasmic part GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle gi|946759756|ref|XP_005864935.2|/3.70813e-105/PREDICTED: anaphase-promoting complex subunit 10 isoform X1 [Myotis brandtii] 20679 8610.16 1.636666667 1.403333333 -0.221902791 Down 0.206918274 Sox6 SRY (sex determining region Y)-box 6 K09269|1|0.0|1416|mmu:20679|transcription factor SOX5/6/13 (SOX group D) GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding GO:0071363//cellular response to growth factor stimulus;GO:0032989;GO:0051094//positive regulation of developmental process;GO:0002062//chondrocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007507//heart development;GO:0010629//negative regulation of gene expression;GO:0043009//chordate embryonic development;GO:0021779//oligodendrocyte cell fate commitment;GO:0030218//erythrocyte differentiation;GO:0072497;GO:0071363//cellular response to growth factor stimulus;GO:0032989;GO:0051094//positive regulation of developmental process;GO:0002062//chondrocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007507//heart development;GO:0010629//negative regulation of gene expression;GO:0043009//chordate embryonic development;GO:0021779//oligodendrocyte cell fate commitment;GO:0030218//erythrocyte differentiation;GO:0072497;GO:0071363//cellular response to growth factor stimulus;GO:0032989;GO:0051094//positive regulation of developmental process;GO:0002062//chondrocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007507//heart development;GO:0010629//negative regulation of gene expression;GO:0043009//chordate embryonic development;GO:0021779//oligodendrocyte cell fate commitment;GO:0030218//erythrocyte differentiation;GO:0072497;GO:0071363//cellular response to growth factor stimulus;GO:0032989;GO:0051094//positive regulation of developmental process;GO:0002062//chondrocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007507//heart development;GO:0010629//negative regulation of gene expression;GO:0043009//chordate embryonic development;GO:0021779//oligodendrocyte cell fate commitment;GO:0030218//erythrocyte differentiation;GO:0072497;GO:0071363//cellular response to growth factor stimulus;GO:0032989;GO:0051094//positive regulation of developmental process;GO:0002062//chondrocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007507//heart development;GO:0010629//negative regulation of gene expression;GO:0043009//chordate embryonic development;GO:0021779//oligodendrocyte cell fate commitment;GO:0030218//erythrocyte differentiation;GO:0072497 gi|6755610|ref|NP_035575.1|/0/transcription factor SOX-6 isoform 1 [Mus musculus] 100380944 1598.07 17.49 16.57666667 -0.077376359 Down 0.206805446 Ino80dos "INO80 complex subunit D, opposite strand" K03934|1|4e-19|98.6|mmu:227197|NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3] - - - - 52206 2668 16.22666667 15.31666667 -0.083264307 Down 0.206805446 Anapc4 anaphase promoting complex subunit 4 K03351|1|0.0|1503|mmu:52206|anaphase-promoting complex subunit 4 GO:0000152//nuclear ubiquitin ligase complex GO:0016741;GO:0046914//transition metal ion binding;GO:0019902//phosphatase binding GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0007088//regulation of mitotic nuclear division gi|23956182|ref|NP_077175.1|/0/anaphase-promoting complex subunit 4 [Mus musculus] 108654 9669 16.41 15.5 -0.082307023 Down 0.206805446 Fam210a "family with sequence similarity 210, member A" K01283|1|2e-14|86.3|ame:726599|peptidyl-dipeptidase A [EC:3.4.15.1] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|24418876|ref|NP_722489.1|/2.92216e-142/protein FAM210A [Mus musculus] 432779 2746 35.82333333 37.51333333 0.066503877 Up 0.20670202 Lrrc14b leucine rich repeat containing 14B - - - - "gi|40675542|gb|AAH64819.1|/0/AI595366 protein, partial [Mus musculus]" 83691 4006 0.75 0.583333333 -0.362570079 Down 0.206673812 Crispld1 cysteine-rich secretory protein LCCL domain containing 1 K19919|1|3e-178|629|gga:415818|cysteine-rich secretory protein - - - gi|123173746|ref|NP_113579.2|/0/cysteine-rich secretory protein LCCL domain-containing 1 precursor [Mus musculus] 231999 6723 1.756666667 1.516666667 -0.211936417 Down 0.20666441 Plekha8 "pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8" K08051|1|0.0|1004|mmu:231999|pleckstrin homology domain containing family A member 8 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:1901981//phosphatidylinositol phosphate binding;GO:0005319//lipid transporter activity;GO:0046625//sphingolipid binding;GO:1901981//phosphatidylinositol phosphate binding;GO:0005319//lipid transporter activity;GO:0046625//sphingolipid binding GO:0045184//establishment of protein localization;GO:0032365//intracellular lipid transport;GO:0045184//establishment of protein localization;GO:0032365//intracellular lipid transport gi|256355025|ref|NP_001157833.1|/0/pleckstrin homology domain-containing family A member 8 isoform 1 [Mus musculus] 170835 3473 11.14 10.48333333 -0.087651716 Down 0.206589191 Inpp5j inositol polyphosphate 5-phosphatase J "K01106|1|0.0|1418|mmu:170835|inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56]" GO:0044424;GO:0031252//cell leading edge;GO:0030425//dendrite;GO:0044425 GO:0046030//inositol trisphosphate phosphatase activity;GO:0034594//phosphatidylinositol trisphosphate phosphatase activity GO:0010975//regulation of neuron projection development;GO:0001933//negative regulation of protein phosphorylation;GO:0046488//phosphatidylinositol metabolic process;GO:0031111//negative regulation of microtubule polymerization or depolymerization gi|26329831|dbj|BAC28654.1|/0/unnamed protein product [Mus musculus] 209225 4523.9 10.13333333 10.79 0.090586042 Up 0.206589191 Zfp710 zinc finger protein 710 K09228|1|1e-78|298|mze:106675525|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|568947568|ref|XP_006540804.1|/0/PREDICTED: zinc finger protein 710 isoform X3 [Mus musculus] 320267 3367.94 3.206666667 3.543333333 0.144032798 Up 0.206579789 Fubp3 far upstream element (FUSE) binding protein 3 K13210|1|0.0|1028|mmu:320267|far upstream element-binding protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|594542459|ref|NP_001277477.1|/0/far upstream element-binding protein 3 isoform b [Mus musculus] 56542 6684.02 3.8 3.46 -0.135227381 Down 0.206579789 Ick intestinal cell kinase K08828|1|0.0|1056|mmu:56542|intestinal cell (MAK-like) kinase [EC:2.7.11.22] - - - - 230872 6355.33 1.143333333 0.946666667 -0.272317647 Down 0.206495167 Crocc "ciliary rootlet coiled-coil, rootletin" K16469|1|0.0|2882|mmu:230872|rootletin - - - gi|225543191|ref|NP_742120.2|/0/rootletin isoform 1 [Mus musculus] 51793 1350 16.27666667 15.38 -0.081749774 Down 0.206448155 Ddah2 dimethylarginine dimethylaminohydrolase 2 K01482|1|4e-128|460|mmu:51793|dimethylargininase [EC:3.5.3.18] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0031406//carboxylic acid binding;GO:0016813//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines;GO:0031406//carboxylic acid binding;GO:0016813//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines" GO:0009064//glutamine family amino acid metabolic process;GO:0006575//cellular modified amino acid metabolic process;GO:0009064//glutamine family amino acid metabolic process;GO:0006575//cellular modified amino acid metabolic process "gi|537254028|gb|ERE88825.1|/9.89831e-126/N(G),N(G)-dimethylarginine dimethylaminohydrolase 2-like isoform 1 [Cricetulus griseus]" 12894 4331 16.36 15.45666667 -0.081943522 Down 0.206448155 Cpt1a "carnitine palmitoyltransferase 1a, liver" "K08765|1|0.0|1555|mmu:12894|carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]" GO:0019866//organelle inner membrane;GO:0031306//intrinsic component of mitochondrial outer membrane GO:0005515//protein binding;GO:0016406//carnitine O-acyltransferase activity GO:0006635//fatty acid beta-oxidation;GO:0006577//amino-acid betaine metabolic process;GO:0006639//acylglycerol metabolic process;GO:0010033//response to organic substance;GO:0051259//protein oligomerization;GO:0019318//hexose metabolic process;GO:0030073//insulin secretion;GO:0007631//feeding behavior;GO:0019217//regulation of fatty acid metabolic process "gi|148700985|gb|EDL32932.1|/0/carnitine palmitoyltransferase 1a, liver, isoform CRA_b, partial [Mus musculus]" 271144 3315 0.526666667 0.376666667 -0.483601786 Down 0.206401143 Ankdd1b ankyrin repeat and death domain containing 1B K18441|1|8e-35|152|aqu:100641148|cytohesin - - - gi|568984535|ref|XP_006517745.1|/0/PREDICTED: ankyrin repeat and death domain-containing protein 1B isoform X2 [Mus musculus] 73251 7356 6.963333333 7.486666667 0.104545435 Up 0.206401143 Setd7 SET domain containing (lysine methyltransferase) 7 K11431|1|0.0|727|ngi:103742371|histone-lysine N-methyltransferase SETD7 [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0016279//protein-lysine N-methyltransferase activity;GO:0005515//protein binding "GO:0018022//peptidyl-lysine methylation;GO:0006351//transcription, DNA-templated;GO:0016571//histone methylation" gi|37360520|dbj|BAC98238.1|/0/mKIAA1717 protein [Mus musculus] 75746 4202.69 1.13 1.343333333 0.249494565 Up 0.206316522 Morc4 microrchidia 4 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0032550;GO:0046914//transition metal ion binding;GO:0032550 - "gi|148691971|gb|EDL23918.1|/0/microrchidia 4, isoform CRA_a, partial [Mus musculus]" 226250 3915 1.326666667 1.116666667 -0.248607335 Down 0.206316522 Afap1l2 actin filament associated protein 1-like 2 K18616|1|5e-113|412|ola:101172963|actin filament associated protein 1 GO:0044424;GO:0044424;GO:0044424 GO:0030295//protein kinase activator activity;GO:0019904//protein domain specific binding;GO:0030295//protein kinase activator activity;GO:0019904//protein domain specific binding;GO:0030295//protein kinase activator activity;GO:0019904//protein domain specific binding "GO:0000278//mitotic cell cycle;GO:0006351//transcription, DNA-templated;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0045860//positive regulation of protein kinase activity;GO:0006952//defense response;GO:0000278//mitotic cell cycle;GO:0006351//transcription, DNA-templated;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0045860//positive regulation of protein kinase activity;GO:0006952//defense response;GO:0000278//mitotic cell cycle;GO:0006351//transcription, DNA-templated;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0045860//positive regulation of protein kinase activity;GO:0006952//defense response" gi|295317357|ref|NP_001171267.1|/0/actin filament-associated protein 1-like 2 isoform 1 [Mus musculus] 223773 5403 1.116666667 1.33 0.252227651 Up 0.206316522 Zbed4 "zinc finger, BED type containing 4" "K14864|1|9e-26|122|aqu:100636976|tRNA (cytidine32/guanosine34-2'-O)-methyltransferase [EC:2.1.1.205];K14312|2|2e-18|98.6|hmg:100212106|nuclear pore complex protein Nup155;K06496|3|2e-16|91.7|lcm:102355208|selectin, platele;K16547|4|1e-11|75.9|hmg:100209833|protein NEDD1;K08073|5|2e-11|75.1|api:100164673|bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]" - - - - 21974 5652 6.176666667 5.726666667 -0.109132845 Down 0.206203693 Top2b topoisomerase (DNA) II beta K03164|1|0.0|2910|mmu:21974|DNA topoisomerase II [EC:5.99.1.3] GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0070603//SWI/SNF superfamily-type complex GO:0008094//DNA-dependent ATPase activity;GO:0032550;GO:0019901//protein kinase binding;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0003677//DNA binding GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007420//brain development;GO:0007059//chromosome segregation;GO:0022402//cell cycle process;GO:0071103//DNA conformation change;GO:0016477//cell migration gi|34328148|ref|NP_033435.2|/0/DNA topoisomerase 2-beta [Mus musculus] 14884 2749 6.333333333 5.883333333 -0.106331235 Down 0.206203693 Gtf2h1 "general transcription factor II H, polypeptide 1" K03141|1|0.0|1049|mmu:14884|transcription initiation factor TFIIH subunit 1 GO:0005667//transcription factor complex;GO:0005667//transcription factor complex "GO:0004674//protein serine/threonine kinase activity;GO:0042623//ATPase activity, coupled;GO:0004674//protein serine/threonine kinase activity;GO:0042623//ATPase activity, coupled" GO:0006281//DNA repair;GO:0006464//cellular protein modification process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006281//DNA repair;GO:0006464//cellular protein modification process;GO:0006366//transcription from RNA polymerase II promoter gi|597517984|ref|NP_001278004.1|/0/general transcription factor IIH subunit 1 isoform 1 [Mus musculus] 19227 1455 0.713333333 0.893333333 0.324622204 Up 0.206194291 Pthlh parathyroid hormone-like peptide - GO:0031981//nuclear lumen;GO:0044421 GO:0051427//hormone receptor binding GO:0030324//lung development;GO:0002062//chondrocyte differentiation;GO:0001649//osteoblast differentiation;GO:0060560//developmental growth involved in morphogenesis;GO:0051604//protein maturation;GO:0008283//cell proliferation;GO:0006171//cAMP biosynthetic process;GO:0036075;GO:0044092//negative regulation of molecular function;GO:0048875//chemical homeostasis within a tissue;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway "gi|148678784|gb|EDL10731.1|/4.04614e-80/parathyroid hormone-like peptide, isoform CRA_a, partial [Mus musculus]" 235135 1602 0.196666667 0.323333333 0.717269793 Up 0.206194291 Tmem45b transmembrane protein 45b - GO:0031224//intrinsic component of membrane - - gi|21450349|ref|NP_659185.1|/7.42167e-163/transmembrane protein 45B [Mus musculus] 26926 2249 33.52666667 31.89333333 -0.072054164 Down 0.206194291 Aifm1 "apoptosis-inducing factor, mitochondrion-associated 1" K04727|1|0.0|1137|mmu:26926|programmed cell death 8 (apoptosis-inducing factor) [EC:1.-.-.-] GO:0031966//mitochondrial membrane;GO:0019866//organelle inner membrane;GO:0031966//mitochondrial membrane;GO:0019866//organelle inner membrane "GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0016649//oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor;GO:0000166//nucleotide binding;GO:0016649//oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor" "GO:0070997//neuron death;GO:0000737//DNA catabolic process, endonucleolytic;GO:0010257//NADH dehydrogenase complex assembly;GO:0006915//apoptotic process;GO:0034976//response to endoplasmic reticulum stress;GO:0044710;GO:0019725//cellular homeostasis;GO:0030154//cell differentiation;GO:0070997//neuron death;GO:0000737//DNA catabolic process, endonucleolytic;GO:0010257//NADH dehydrogenase complex assembly;GO:0006915//apoptotic process;GO:0034976//response to endoplasmic reticulum stress;GO:0044710;GO:0019725//cellular homeostasis;GO:0030154//cell differentiation" "gi|594150372|ref|NP_001277293.1|/0/apoptosis-inducing factor 1, mitochondrial isoform 2 [Mus musculus]" 76117 2663 0.2 0.33 0.722466024 Up 0.206194291 Arhgap15 Rho GTPase activating protein 15 K01556|1|1e-135|486|xtr:100485536|kynureninase [EC:3.7.1.3];K20315|2|6e-32|142|aec:105149722|Rho GTPase-activating protein 21/23 GO:0044424;GO:0044424;GO:0044424 GO:0008289//lipid binding;GO:0008289//lipid binding;GO:0008289//lipid binding GO:0022604//regulation of cell morphogenesis;GO:0022604//regulation of cell morphogenesis;GO:0022604//regulation of cell morphogenesis "gi|148694910|gb|EDL26857.1|/0/Rho GTPase activating protein 15, isoform CRA_e, partial [Mus musculus]" 18005 3218 0.2 0.33 0.722466024 Up 0.206194291 Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 K08857|1|0.0|816|mmu:18005|NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] "GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0000775//chromosome, centromeric region;GO:0000228//nuclear chromosome" GO:0032550;GO:0004672//protein kinase activity;GO:0043169//cation binding;GO:0019902//phosphatase binding GO:0007098//centrosome cycle;GO:0007052//mitotic spindle organization;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0051100//negative regulation of binding;GO:0006468//protein phosphorylation;GO:0000087//mitotic M phase;GO:0001701//in utero embryonic development gi|190684657|ref|NP_035022.2|/0/serine/threonine-protein kinase Nek2 [Mus musculus] 27384 1232 0.733333333 0.916666667 0.321928095 Up 0.206194291 Akr1c13 "aldo-keto reductase family 1, member C13" K13374|1|0.0|665|mmu:27384|aldo-keto reductase family 1 member C13 [EC:1.1.1.218];K04119|2|7e-157|555|ngi:103725887|aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357];K00212|5|3e-130|467|cjc:100404656|20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20] - GO:0003824//catalytic activity GO:0044710;GO:0044237//cellular metabolic process gi|60360212|dbj|BAD90350.1|/0/mKIAA4014 protein [Mus musculus] 100503460 416 0.14 0.26 0.893084796 Up 0.206194291 Gm19705 "predicted gene, 19705" - - - - - 30841 4102.9 4.48 4.88 0.123382416 Up 0.206156681 Kdm2b lysine (K)-specific demethylase 2B K10276|1|0.0|2355|mmu:30841|F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27] GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0046914//transition metal ion binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0032451//demethylase activity;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0032451//demethylase activity;GO:0003723//RNA binding" "GO:0010390//histone monoubiquitination;GO:0030917//midbrain-hindbrain boundary development;GO:0006366//transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0006482//protein demethylation;GO:0008285//negative regulation of cell proliferation;GO:0021591//ventricular system development;GO:0001843//neural tube closure;GO:0031076//embryonic camera-type eye development;GO:0048232//male gamete generation;GO:0021537//telencephalon development;GO:0006351//transcription, DNA-templated;GO:0010390//histone monoubiquitination;GO:0030917//midbrain-hindbrain boundary development;GO:0043066//negative regulation of apoptotic process;GO:0006482//protein demethylation;GO:0008285//negative regulation of cell proliferation;GO:0021591//ventricular system development;GO:0001843//neural tube closure;GO:0031076//embryonic camera-type eye development;GO:0048232//male gamete generation;GO:0021537//telencephalon development" gi|39930339|ref|NP_038938.1|/0/lysine-specific demethylase 2B isoform 2 [Mus musculus] 22693 2604 5.053333333 4.65 -0.120004631 Down 0.206156681 Zfp30 zinc finger protein 30 K09228|1|0.0|1172|mmu:22693|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|7305645|ref|NP_038733.1|/0/zinc finger protein 30 [Mus musculus] 72805 3644.65 4.663333333 5.06 0.117775828 Up 0.206156681 Zfp839 zinc finger protein 839 - - - - gi|241897001|ref|NP_082641.1|/0/zinc finger protein 839 isoform 1 [Mus musculus] 76294 1579 4.976666667 4.576666667 -0.12088254 Down 0.206156681 Asb5 ankyrin repeat and SOCs box-containing 5 K10327|1|0.0|654|cge:100752543|ankyrin repeat and SOCS box protein 5 - - GO:0007165//signal transduction gi|625215804|ref|XP_003509596.2|/0/PREDICTED: ankyrin repeat and SOCS box protein 5 isoform X1 [Cricetulus griseus] 226641 7463 16.03 15.13666667 -0.082726889 Down 0.206156681 Atf6 activating transcription factor 6 K09054|1|0.0|1110|mmu:226641|cyclic AMP-dependent transcription factor ATF-6 alpha - - - gi|26331318|dbj|BAC29389.1|/0/unnamed protein product [Mus musculus] 214627 4641.83 4.853333333 4.453333333 -0.124090348 Down 0.206156681 Papd5 PAP associated domain containing 5 K03514|1|0.0|1044|mmu:214627|non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0034061//DNA polymerase activity;GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0034061//DNA polymerase activity;GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0034061//DNA polymerase activity GO:0006259//DNA metabolic process;GO:0000087//mitotic M phase;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006259//DNA metabolic process;GO:0000087//mitotic M phase;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006259//DNA metabolic process;GO:0000087//mitotic M phase;GO:0000956//nuclear-transcribed mRNA catabolic process gi|256818784|ref|NP_001157969.1|/0/non-canonical poly(A) RNA polymerase PAPD5 isoform a [Mus musculus] 18951 2155 4.593333333 4.99 0.119498333 Up 0.206156681 5-Sep septin 5 K04557|1|0.0|732|mmu:18951|septin 5 GO:0032156//septin cytoskeleton;GO:0016020//membrane;GO:0032432//actin filament bundle;GO:0032155;GO:0033267;GO:0030136//clathrin-coated vesicle GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0000149//SNARE binding;GO:0005543//phospholipid binding;GO:0042802//identical protein binding GO:0006887//exocytosis;GO:0009154//purine ribonucleotide catabolic process;GO:0006903//vesicle targeting gi|158508501|ref|NP_998779.2|/0/septin-5 [Mus musculus] 60406 1183 5.19 4.79 -0.115708883 Down 0.206156681 Sap30 sin3 associated polypeptide K19202|1|3e-67|258|mmu:60406|histone deacetylase complex subunit SAP30 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005488//binding;GO:0003712//transcription cofactor activity GO:0007519//skeletal muscle tissue development;GO:0006366//transcription from RNA polymerase II promoter gi|12408290|ref|NP_068560.1|/2.4729e-66/histone deacetylase complex subunit SAP30 [Mus musculus] 15199 1065 10.25333333 9.603333333 -0.094485843 Down 0.206109669 Hebp1 heme binding protein 1 K01942|1|2e-16|89.4|tup:102498435|biotin--protein ligase [EC:6.3.4.9 6.3.4.10 6.3.4.11 6.3.4.15] - - - - 20392 1730.57 10.21666667 10.86333333 0.088542278 Up 0.206109669 Sgce "sarcoglycan, epsilon" K12565|1|5e-102|374|pbi:103054718|alpha-sarcoglycan GO:0016011//dystroglycan complex;GO:0016021//integral component of membrane;GO:0043232;GO:0043232;GO:0016011//dystroglycan complex;GO:0016021//integral component of membrane - GO:0007399//nervous system development gi|194328788|ref|NP_001123661.1|/0/epsilon-sarcoglycan isoform 2 [Mus musculus] 234699 4803 10.96666667 10.32 -0.087682112 Down 0.206109669 Edc4 enhancer of mRNA decapping 4 K12616|1|0.0|2375|mmu:234699|enhancer of mRNA-decapping protein 4 GO:0035770//ribonucleoprotein granule;GO:0031981//nuclear lumen;GO:0035770//ribonucleoprotein granule;GO:0031981//nuclear lumen GO:0005488//binding;GO:0005488//binding - "gi|148679377|gb|EDL11324.1|/0/enhancer of mRNA decapping 4, isoform CRA_a, partial [Mus musculus]" 74717 1070 0.383333333 0.53 0.467392904 Up 0.206053255 Spata17 spermatogenesis associated 17 - GO:0044424;GO:0044424 GO:0005515//protein binding;GO:0005515//protein binding - gi|190610015|ref|NP_083343.1|/3.03646e-81/spermatogenesis-associated protein 17 isoform 2 [Mus musculus] 51944 3118 0.393333333 0.543333333 0.466085105 Up 0.206053255 Knstrn kinetochore-localized astrin/SPAG5 binding - GO:0043231//intracellular membrane-bounded organelle;GO:0005874//microtubule;GO:0000776//kinetochore;GO:0005819//spindle GO:0005488//binding GO:0008608//attachment of spindle microtubules to kinetochore;GO:0000819//sister chromatid segregation;GO:0007067//mitotic nuclear division "gi|148695980|gb|EDL27927.1|/9.52682e-150/DNA segment, Chr 2, ERATO Doi 750, expressed, isoform CRA_d, partial [Mus musculus]" 99326 3387 0.536666667 0.386666667 -0.472935883 Down 0.206053255 Garnl3 GTPase activating RANGAP domain-like 3 K17700|1|4e-54|216|tca:661653|RAP1 GTPase activating protein 1 - GO:0008047//enzyme activator activity;GO:0030695//GTPase regulator activity GO:0007264//small GTPase mediated signal transduction gi|31542097|ref|NP_849219.2|/0/GTPase-activating Rap/Ran-GAP domain-like protein 3 [Mus musculus] 228482 5017 0.543333333 0.393333333 -0.466085105 Down 0.206053255 Arhgap11a Rho GTPase activating protein 11A K20122|1|2e-16|91.7|myb:102245709|Rho GTPase-activating protein 4;K18470|2|1e-15|89.0|aag:AaeL_AAEL009085|Rho GTPase-activating protein 1 - - - gi|37359732|dbj|BAC97844.1|/0/mKIAA0013 protein [Mus musculus] 216344 1856 34.51 32.9 -0.06892689 Down 0.205987438 Rab21 "RAB21, member RAS oncogene family" K07890|1|7e-110|400|rno:299799|Ras-related protein Rab-21 GO:0012506//vesicle membrane;GO:0005769//early endosome GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction gi|51948448|ref|NP_001004238.1|/5.73727e-109/ras-related protein Rab-21 [Rattus norvegicus] 19277 4096 1.06 0.866666667 -0.290515142 Down 0.205752379 Ptpro "protein tyrosine phosphatase, receptor type, O" K18035|1|0.0|869|mmu:19277|receptor-type tyrosine-protein phosphatase O [EC:3.1.3.48] GO:0016021//integral component of membrane;GO:0031252//cell leading edge;GO:0030425//dendrite;GO:0044459;GO:0016021//integral component of membrane;GO:0031252//cell leading edge;GO:0030425//dendrite;GO:0044459;GO:0030425//dendrite;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0016021//integral component of membrane;GO:0031252//cell leading edge;GO:0030425//dendrite;GO:0044459 GO:0004725//protein tyrosine phosphatase activity;GO:0042802//identical protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0042802//identical protein binding;GO:0004721//phosphoprotein phosphatase activity;GO:0042802//identical protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0042802//identical protein binding GO:0061318;GO:0050922//negative regulation of chemotaxis;GO:0032989;GO:0007162//negative regulation of cell adhesion;GO:0010975//regulation of neuron projection development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030031//cell projection assembly;GO:0036058//filtration diaphragm assembly;GO:0006470//protein dephosphorylation;GO:0003093//regulation of glomerular filtration;GO:0030595//leukocyte chemotaxis;GO:0061318;GO:0050922//negative regulation of chemotaxis;GO:0032989;GO:0007162//negative regulation of cell adhesion;GO:0010975//regulation of neuron projection development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030031//cell projection assembly;GO:0036058//filtration diaphragm assembly;GO:0006470//protein dephosphorylation;GO:0003093//regulation of glomerular filtration;GO:0030595//leukocyte chemotaxis;GO:0061318;GO:0032989;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030031//cell projection assembly;GO:0036058//filtration diaphragm assembly;GO:0006470//protein dephosphorylation;GO:0003093//regulation of glomerular filtration;GO:0030595//leukocyte chemotaxis;GO:0061318;GO:0050922//negative regulation of chemotaxis;GO:0032989;GO:0007162//negative regulation of cell adhesion;GO:0010975//regulation of neuron projection development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030031//cell projection assembly;GO:0036058//filtration diaphragm assembly;GO:0006470//protein dephosphorylation;GO:0003093//regulation of glomerular filtration;GO:0030595//leukocyte chemotaxis gi|7958608|gb|AAF70856.1|AF135166_1/0/glomerular epithelial protein 1 precursor [Mus musculus] 209462 3785 0.873333333 1.066666667 0.288505093 Up 0.205752379 Hace1 "HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1" K12166|1|0.0|1838|mmu:209462|E3 ubiquitin-protein ligase HACE1 [EC:2.3.2.26] - - - - 214150 7635 0.436666667 0.293333333 -0.573991383 Down 0.205695964 Ago3 argonaute RISC catalytic subunit 3 K11593|1|0.0|1737|mmu:214150|eukaryotic translation initiation factor 2C GO:0035770//ribonucleoprotein granule;GO:0044444//cytoplasmic part "GO:0008135//translation factor activity, RNA binding" GO:0006412//translation;GO:0006401//RNA catabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0035195//gene silencing by miRNA gi|240120065|ref|NP_700451.2|/0/protein argonaute-3 [Mus musculus] 110751 3098 0.286666667 0.426666667 0.573735245 Up 0.205695964 Adam33 a disintegrin and metallopeptidase domain 33 K08616|1|0.0|1550|mmu:110751|disintegrin and metalloproteinase domain-containing protein 33 [EC:3.4.24.-] - - - - 16502 7788 0.28 0.416666667 0.573466862 Up 0.205695964 Kcnc1 "potassium voltage gated channel, Shaw-related subfamily, member 1" K04887|1|0.0|1035|ptr:466452|potassium voltage-gated channel Shaw-related subfamily C member 1 - - - gi|332835957|ref|XP_001172719.2|/0/PREDICTED: potassium voltage-gated channel subfamily C member 1 isoform X1 [Pan troglodytes] 231380 5101 0.43 0.29 -0.56828376 Down 0.205695964 Uba6 ubiquitin-like modifier activating enzyme 6 K10699|1|0.0|2102|mmu:231380|ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45] - - - - 232685 1645 0.416666667 0.28 -0.573466862 Down 0.205695964 Lncpint "long non-protein coding RNA, Trp53 induced transcript" - - - - gi|148681773|gb|EDL13720.1|/4.35661e-12/cDNA sequence AB041803 [Mus musculus] 70432 8936 2.513333333 2.233333333 -0.170403428 Down 0.205611343 Rufy2 RUN and FYVE domain-containing 2 K10742|1|0.0|956|cjo:107315722|DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12];K12482|2|0.0|677|acs:100565421|RUN and FYVE domain-containing protein 1 GO:0031981//nuclear lumen GO:0043169//cation binding - gi|50510975|dbj|BAD32473.1|/0/mKIAA1537 protein [Mus musculus] 13143 1792 2.493333333 2.213333333 -0.171855029 Down 0.205611343 Dapk2 death-associated protein kinase 2 K08803|1|0.0|730|mmu:13143|death-associated protein kinase [EC:2.7.11.1] GO:0031982//vesicle;GO:0005775//vacuolar lumen GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding GO:0012502//induction of programmed cell death;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0006915//apoptotic process;GO:0006914//autophagy gi|34328167|ref|NP_034149.2|/0/death-associated protein kinase 2 [Mus musculus] 108015 3486 0.256666667 0.14 -0.874469118 Down 0.205601941 Chrnb4 "cholinergic receptor, nicotinic, beta polypeptide 4" K04815|1|0.0|955|mmu:108015|nicotinic acetylcholine receptor beta-4 GO:0042995//cell projection;GO:0097060//synaptic membrane;GO:0005887//integral component of plasma membrane GO:0004888//transmembrane signaling receptor activity;GO:0042165//neurotransmitter binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0007274//neuromuscular synaptic transmission;GO:0051259//protein oligomerization;GO:0044765//single-organism transport;GO:0014070//response to organic cyclic compound;GO:0006937//regulation of muscle contraction;GO:0042391//regulation of membrane potential;GO:0030534//adult behavior gi|33563301|ref|NP_683746.1|/0/neuronal acetylcholine receptor subunit beta-4 precursor [Mus musculus] 27966 1537 14.53 15.39666667 0.083583342 Up 0.205592538 Rrp9 "RRP9, small subunit (SSU) processome component, homolog (yeast)" K14793|1|0.0|802|mmu:27966|ribosomal RNA-processing protein 9 GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding GO:0042254//ribosome biogenesis gi|21704248|ref|NP_663595.1|/0/U3 small nucleolar RNA-interacting protein 2 [Mus musculus] 14865 1671.37 6.876666667 7.39 0.103864949 Up 0.205536124 Gstm4 "glutathione S-transferase, mu 4" K00799|1|5e-118|427|rno:499689|glutathione S-transferase [EC:2.5.1.18] GO:0044444//cytoplasmic part;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane "GO:0042802//identical protein binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0072341//modified amino acid binding;GO:0042802//identical protein binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0072341//modified amino acid binding" GO:0044710;GO:0006805//xenobiotic metabolic process;GO:0006790//sulfur compound metabolic process;GO:0006807//nitrogen compound metabolic process;GO:0044710;GO:0006805//xenobiotic metabolic process;GO:0006790//sulfur compound metabolic process;GO:0006807//nitrogen compound metabolic process "gi|148669993|gb|EDL01940.1|/4.55154e-134/mCG144942, isoform CRA_a, partial [Mus musculus]" 17199 3670 0.49 0.646666667 0.400240497 Up 0.205517319 Mc1r melanocortin 1 receptor K04199|1|3e-147|525|mmu:17199|melanocortin 1 receptor;K07375|5|3e-113|412|cfr:102511248|tubulin beta - - - - 102633673 437 0.643333333 0.486666667 -0.402632478 Down 0.205517319 Etaa1os "Ewing tumor-associated antigen 1, opposite strand" - - - - - 69815 922 0.996666667 1.196666667 0.26383836 Up 0.205460905 Krtcap3 keratinocyte associated protein 3 - GO:0031224//intrinsic component of membrane - - gi|20381302|gb|AAH27812.1|/2.36267e-105/Krtcap3 protein [Mus musculus] 108652 1929 1.03 1.23 0.256013978 Up 0.205460905 Slc35b3 "solute carrier family 35, member B3" "K15277|1|0.0|742|rno:306866|solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763 gi|281371347|ref|NP_001163902.1|/0/adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform 1 [Mus musculus] 217310 3237 1.013333333 1.21 0.255898225 Up 0.205460905 Hid1 HID1 domain containing - GO:0031312;GO:0031985//Golgi cisterna;GO:0005874//microtubule - GO:0014070//response to organic cyclic compound;GO:0015031//protein transport "gi|148702530|gb|EDL34477.1|/0/RIKEN cDNA C630004H02, isoform CRA_a, partial [Mus musculus]" 72429 1827 10.20333333 9.563333333 -0.093455077 Down 0.205423295 Dnajc25 DnaJ heat shock protein family (Hsp40) member C25 K19371|1|6e-124|447|mmu:72429|DnaJ homolog subfamily C member 25 - - - - 230709 3430 9.64 10.28 0.092735213 Up 0.205423295 Zmpste24 "zinc metallopeptidase, STE24" K06013|1|0.0|873|mmu:230709|STE24 endopeptidase [EC:3.4.24.84] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0004175//endopeptidase activity;GO:0043169//cation binding GO:0019941//modification-dependent protein catabolic process;GO:0006997//nucleus organization gi|27370012|ref|NP_766288.1|/0/CAAX prenyl protease 1 homolog [Mus musculus] 71709 3288 10.14 10.77666667 0.087853354 Up 0.205423295 Syde1 "synapse defective 1, Rho GTPase, homolog 1 (C. elegans)" K08878|1|6e-22|109|chx:102174329|breakpoint cluster region protein [EC:2.7.11.1] GO:0044464 GO:0008047//enzyme activator activity GO:0007154//cell communication gi|226442819|ref|NP_082151.1|/0/rho GTPase-activating protein SYDE1 [Mus musculus] 69940 3345.4 4.016666667 3.66 -0.134155092 Down 0.205366881 Exoc1 exocyst complex component 1 K19983|1|0.0|1669|mmu:69940|exocyst complex component 1 - - GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport gi|576796187|ref|NP_001276700.1|/0/exocyst complex component 1 isoform 3 [Mus musculus] 232491 2155 3.85 4.213333333 0.130103612 Up 0.205366881 Pyroxd1 pyridine nucleotide-disulphide oxidoreductase domain 1 "K16174|1|3e-124|448|ame:552526|small subunit ribosomal protein S18b, mitochondrial" - GO:0003824//catalytic activity GO:0044710 gi|110625837|ref|NP_898988.2|/0/pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 [Mus musculus] 66244 3737 3.786666667 4.146666667 0.131023651 Up 0.205366881 Nemf nuclear export mediator factor - - - - - 54208 2154 14.63333333 15.49 0.082078705 Up 0.20528226 Arl6ip1 ADP-ribosylation factor-like 6 interacting protein 1 - GO:0071256;GO:0031224//intrinsic component of membrane - GO:0006612//protein targeting to membrane gi|6739575|gb|AAF27313.1|AF172088_1/6.62111e-128/TBX2 protein [Mus musculus] 68795 8087.94 16.23333333 15.37666667 -0.07821648 Down 0.20528226 Ubr3 ubiquitin protein ligase E3 component n-recognin 3 K11978|1|0.0|3531|mmu:68795|E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27] - - - gi|733215968|ref|NP_001289962.1|/0/E3 ubiquitin-protein ligase UBR3 isoform 3 [Mus musculus] 72459 2849.4 15.71 14.84666667 -0.081544123 Down 0.20528226 Htatsf1 HIV TAT specific factor 1 K13093|1|0.0|1018|mmu:72459|HIV Tat-specific factor 1 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006354//DNA-templated transcription, elongation;GO:0019058//viral life cycle;GO:0006366//transcription from RNA polymerase II promoter;GO:0006354//DNA-templated transcription, elongation;GO:0019058//viral life cycle;GO:0006366//transcription from RNA polymerase II promoter" "gi|148710216|gb|EDL42162.1|/0/HIV TAT specific factor 1, isoform CRA_b, partial [Mus musculus]" 76080 4531.12 3.13 2.82 -0.150467495 Down 0.20528226 Ttpal tocopherol (alpha) transfer protein-like K19625|1|6e-15|69.3|oaa:100082169|retinaldehyde-binding protein 1 GO:0044464 - GO:0051234//establishment of localization gi|802083927|ref|NP_001292732.1|/0/alpha-tocopherol transfer protein-like isoform 2 [Mus musculus] 14211 5455 0.306666667 0.45 0.553253641 Up 0.205160029 Smc2 structural maintenance of chromosomes 2 K06674|1|0.0|2066|mmu:14211|structural maintenance of chromosome 2 GO:0043231//intracellular membrane-bounded organelle;GO:0000793//condensed chromosome GO:0032550;GO:0046983//protein dimerization activity GO:0000070//mitotic sister chromatid segregation;GO:0030261//chromosome condensation gi|62990166|ref|NP_032043.3|/0/structural maintenance of chromosomes protein 2 [Mus musculus] 192170 1489 32.25666667 33.79 0.066998989 Up 0.20508481 Eif4a3 eukaryotic translation initiation factor 4A3 K13025|1|0.0|785|mmu:192170|ATP-dependent RNA helicase [EC:3.6.4.13] GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0003724//RNA helicase activity;GO:0032550;GO:0008135//translation factor activity, RNA binding;GO:0042623//ATPase activity, coupled;GO:0003729//mRNA binding" "GO:0007166//cell surface receptor signaling pathway;GO:0050658//RNA transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0006412//translation;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000398//mRNA splicing, via spliceosome;GO:0042254//ribosome biogenesis" gi|20149756|ref|NP_619610.1|/0/eukaryotic initiation factor 4A-III [Mus musculus] 100042499 2346 0.22 0.353333333 0.683526335 Up 0.20508481 Vmn2r55 "vomeronasal 2, receptor 55" K04612|1|0.0|1049|cge:103163658|calcium-sensing receptor - - - "gi|157278024|ref|NP_001098115.1|/0/vomeronasal 2, receptor 55 [Mus musculus]" 70194 449 0.353333333 0.22 -0.683526335 Down 0.20508481 2310075C17Rik RIKEN cDNA 2310075C17 gene - - - - - 59031 1802 5.48 5.916666667 0.110608726 Up 0.205018993 Chst12 carbohydrate sulfotransferase 12 K04742|1|0.0|872|mmu:59031|chondroitin 4-sulfotransferase 12 [EC:2.8.2.5] GO:0031224//intrinsic component of membrane GO:0034481//chondroitin sulfotransferase activity GO:0044723;GO:0006024//glycosaminoglycan biosynthetic process gi|157266279|ref|NP_067503.3|/0/carbohydrate sulfotransferase 12 [Mus musculus] 67048 4273.58 5.343333333 5.783333333 0.114161237 Up 0.205018993 Vma21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) - GO:0044444//cytoplasmic part;GO:0043229//intracellular organelle;GO:0016020//membrane;GO:0000323//lytic vacuole;GO:0012507//ER to Golgi transport vesicle membrane - GO:0070070//proton-transporting V-type ATPase complex assembly gi|667314282|ref|XP_008585718.1|/3.1763e-26/PREDICTED: vacuolar ATPase assembly integral membrane protein VMA21 [Galeopterus variegatus] 218629 4098 6.193333333 5.756666667 -0.105482419 Down 0.205018993 Dhx29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 K18995|1|0.0|2449|mmu:218629|ATP-dependent RNA helicase DHX29 [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle "GO:0008135//translation factor activity, RNA binding;GO:0042623//ATPase activity, coupled;GO:0032550" GO:0006412//translation "gi|148686456|gb|EDL18403.1|/0/DEAH (Asp-Glu-Ala-His) box polypeptide 29, isoform CRA_b, partial [Mus musculus]" 77087 8737.92 15.19666667 14.34666667 -0.083039331 Down 0.205000188 Ankrd11 ankyrin repeat domain 11 K10683|1|2e-30|139|acs:100563125|BRCA1-associated RING domain protein 1 - - - gi|323423025|ref|NP_001074848.2|/0/ankyrin repeat domain-containing protein 11 [Mus musculus] 100504446 1350 0.516666667 0.676666667 0.389211512 Up 0.204934371 Prr22 proline rich 22 K16483|1|7e-21|104|ocu:100351051|centrosomal protein POC5 - - - gi|307548932|ref|NP_001182602.1|/0/proline-rich protein 22 [Mus musculus] 20621 2919 9.41 10.03666667 0.093013579 Up 0.204896762 Snn stannin - GO:0016020//membrane;GO:0005739//mitochondrion - GO:0050896//response to stimulus gi|795445199|ref|XP_011885944.1|/3.59779e-32/PREDICTED: stannin [Cercocebus atys] 78185 3456 0.143333333 0.26 0.859137464 Up 0.204868555 Ppp1r3fos "protein phosphatase 1, regulatory subunit 3F, opposite strand" K17453|1|4e-23|113|mmu:54646|protein phosphatase 1 regulatory subunit 3F - - - gi|26348385|dbj|BAC37832.1|/3.90503e-59/unnamed protein product [Mus musculus] 18552 6119.8 2.043333333 1.796666667 -0.185601801 Down 0.204699312 Pcsk5 proprotein convertase subtilisin/kexin type 5 K08654|1|0.0|1880|rno:116548|proprotein convertase subtilisin/kexin type 5 [EC:3.4.21.-] - - - gi|253314509|ref|NP_001156616.1|/0/proprotein convertase subtilisin/kexin type 5 isoform 2 preproprotein [Mus musculus] 70973 473 0.55 0.403333333 -0.447458977 Down 0.204699312 4931431B13Rik RIKEN cDNA 4931431B13 gene K06594|1|6e-18|91.7|mmu:381924|integrin alpha D - - - - 74430 2751 2.07 1.816666667 -0.188337039 Down 0.204699312 4930452B06Rik RIKEN cDNA 4930452B06 gene - - - - gi|254587945|ref|NP_083210.3|/0/uncharacterized protein C3orf67 homolog [Mus musculus] 13996 3135 3.096666667 3.423333333 0.14468568 Up 0.204605288 Etohd2 ethanol decreased 2 - - - - - 13025 955.64 4.746666667 4.353333333 -0.124794249 Down 0.204595886 Ctla2b cytotoxic T lymphocyte-associated protein 2 beta K01365|1|2e-31|138|cge:100756494|cathepsin L [EC:3.4.22.15];K09601|5|3e-24|114|rno:498688|cathepsin R [EC:3.4.22.-] GO:0043005//neuron projection;GO:0043005//neuron projection GO:0005488//binding;GO:0005488//binding GO:0006954//inflammatory response;GO:0045066//regulatory T cell differentiation;GO:0010466//negative regulation of peptidase activity;GO:0016485//protein processing;GO:0006954//inflammatory response;GO:0045066//regulatory T cell differentiation;GO:0010466//negative regulation of peptidase activity;GO:0016485//protein processing gi|50591|emb|CAA33615.1|/2.29829e-77/ctla-2-beta protein (141 AA) [Mus musculus] 234814 1834.14 4.306666667 4.693333333 0.124041264 Up 0.204595886 Mthfsd methenyltetrahydrofolate synthetase domain containing - - GO:0032550;GO:0003676//nucleic acid binding;GO:0016882//cyclo-ligase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0016882//cyclo-ligase activity GO:0006760//folic acid-containing compound metabolic process;GO:0006760//folic acid-containing compound metabolic process gi|262050633|ref|NP_001159954.1|/0/methenyltetrahydrofolate synthase domain-containing protein isoform 1 [Mus musculus] 235610 2572 4.54 4.926666667 0.117919566 Up 0.204595886 Atrip ATR interacting protein K10905|1|0.0|1381|mmu:235610|ATR interacting protein - - - - 223601 3808 4.7 4.313333333 -0.123857545 Down 0.204595886 Fam49b "family with sequence similarity 49, member B" - GO:0043231//intracellular membrane-bounded organelle - - gi|655698052|ref|XP_008254126.1|/2.55891e-176/PREDICTED: protein FAM49B isoform X1 [Oryctolagus cuniculus] 66364 499 14.73666667 15.57666667 0.079976303 Up 0.204586483 2310009A05Rik RIKEN cDNA 2310009A05 gene - - - - gi|817050435|ref|NP_001295354.1|/3.07246e-13/uncharacterized protein LOC66364 [Mus musculus] 228785 2948 0.303333333 0.44 0.536599479 Up 0.204586483 Mylk2 "myosin, light polypeptide kinase 2, skeletal muscle" K00907|1|0.0|1063|mmu:228785|myosin-light-chain kinase [EC:2.7.11.18] - - - - 56726 2856 7.24 7.74 0.096343869 Up 0.204548874 Sh3bgrl SH3-binding domain glutamic acid-rich protein like "K03877|1|1e-34|151|tgu:100227439|beta-1,3-galactosyltransferase 5 [EC:2.4.1.-];K13912|2|3e-08|63.5|xma:102221819|deleted in malignant brain tumors 1 protein" GO:0043231//intracellular membrane-bounded organelle "GO:0030674//protein binding, bridging;GO:0019904//protein domain specific binding" - gi|537127177|gb|ERE65334.1|/9.79449e-61/SH3 domain-binding glutamic acid-rich-like protein [Cricetulus griseus] 24087 3369 0.153333333 0.053333333 -1.523561956 Down 0.204548874 Tll2 tolloid-like 2 K13047|1|0.0|2071|mmu:24087|tolloid-like protein 2 [EC:3.4.24.-] - "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0048869//cellular developmental process gi|6755807|ref|NP_036034.1|/0/tolloid-like protein 2 precursor [Mus musculus] 80909 4807 7.346666667 7.85 0.095602836 Up 0.204548874 Gatsl2 GATS protein-like 2 K19944|1|3e-95|353|gfr:102042531|TBC1 domain family member 10 - - - gi|37674263|ref|NP_109644.2|/2.98487e-177/GATS-like protein 2 [Mus musculus] 547109 1836 0.153333333 0.053333333 -1.523561956 Down 0.204548874 Trim43a tripartite motif-containing 43A K12019|1|0.0|922|mmu:547109|tripartite motif-containing protein 43/48/49/64/77 GO:0044464 GO:0046914//transition metal ion binding - gi|85702270|ref|NP_001030078.1|/0/tripartite motif-containing protein 43A [Mus musculus] 99439 5267 0.34 0.213333333 -0.672425342 Down 0.204426643 Duox1 dual oxidase 1 K13411|1|0.0|3045|mmu:99439|dual oxidase [EC:1.6.3.1 1.11.1.-] - - - - 55985 1162 0.213333333 0.34 0.672425342 Up 0.204426643 Cxcl13 chemokine (C-X-C motif) ligand 13 K10032|1|1e-47|192|mmu:55985|C-X-C motif chemokine 13 GO:0044421 GO:0045236//CXCR chemokine receptor binding;GO:0005539//glycosaminoglycan binding;GO:0048020//CCR chemokine receptor binding;GO:0005125//cytokine activity;GO:0019838//growth factor binding;GO:0046983//protein dimerization activity GO:0048534//hematopoietic or lymphoid organ development;GO:0006952//defense response;GO:0022409//positive regulation of cell-cell adhesion;GO:0035768//endothelial cell chemotaxis to fibroblast growth factor;GO:0010469//regulation of receptor activity;GO:0019221//cytokine-mediated signaling pathway;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0002518//lymphocyte chemotaxis across high endothelial venule;GO:0031334//positive regulation of protein complex assembly;GO:0051480//regulation of cytosolic calcium ion concentration gi|9256521|ref|NP_061354.1|/1.23512e-46/C-X-C motif chemokine 13 precursor [Mus musculus] 74016 3743 0.636666667 0.806666667 0.341434409 Up 0.204360826 Phf19 PHD finger protein 19 K11486|1|0.0|1096|mmu:74016|polycomb-like protein 3 GO:0043231//intracellular membrane-bounded organelle GO:0042393//histone binding;GO:0046914//transition metal ion binding "GO:0031062//positive regulation of histone methylation;GO:0006351//transcription, DNA-templated" gi|21311998|ref|NP_082992.1|/0/PHD finger protein 19 [Mus musculus] 380773 427 30.40666667 31.87666667 0.068113106 Up 0.204351424 Slirp SRA stem-loop interacting RNA binding protein K18159|1|3e-10|65.5|bmy:Bm1_51975|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1;K03102|3|1e-08|60.5|dvi:Dvir_GJ23113|squid GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0036094//small molecule binding "GO:0000957//mitochondrial RNA catabolic process;GO:0006351//transcription, DNA-templated" "gi|283046784|ref|NP_081234.2|/2.93194e-58/SRA stem-loop-interacting RNA-binding protein, mitochondrial [Mus musculus]" 19075 1533 0.903333333 1.093333333 0.275402963 Up 0.204295009 Prim1 "DNA primase, p49 subunit" K02684|1|0.0|868|mmu:19075|DNA primase small subunit [EC:2.7.7.-] GO:0031981//nuclear lumen;GO:0005657//replication fork GO:0003899//DNA-directed RNA polymerase activity;GO:0043169//cation binding GO:0000723//telomere maintenance;GO:0044772//mitotic cell cycle phase transition;GO:0006261//DNA-dependent DNA replication;GO:0051320;GO:0010467//gene expression gi|6679459|ref|NP_032947.1|/0/DNA primase small subunit [Mus musculus] 18515 2801 10.09666667 10.71666667 0.085977159 Up 0.204295009 Pbx2 pre B cell leukemia homeobox 2 K15609|1|0.0|658|mmu:18515|pre-B-cell leukemia transcription factor 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding GO:0003002//regionalization;GO:0035108//limb morphogenesis;GO:0006366//transcription from RNA polymerase II promoter gi|56388825|gb|AAH87615.1|/0/Pre B-cell leukemia transcription factor 2 [Mus musculus] 20725 3075 1.083333333 0.893333333 -0.278206717 Down 0.204295009 Serpinb8 "serine (or cysteine) peptidase inhibitor, clade B, member 8" K13965|1|5e-135|483|mmu:20725|serpin B8 GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity GO:0051346//negative regulation of hydrolase activity;GO:0010466//negative regulation of peptidase activity "gi|148707896|gb|EDL39843.1|/0/serine (or cysteine) peptidase inhibitor, clade B, member 8, isoform CRA_b, partial [Mus musculus]" 17858 2428 1.353333333 1.143333333 -0.243271151 Down 0.204285607 Mx2 MX dynamin-like GTPase 2 K14754|1|0.0|812|mmu:17858|interferon-induced GTP-binding protein Mx1 GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0019079//viral genome replication;GO:0006952//defense response;GO:0051707//response to other organism;GO:0009154//purine ribonucleotide catabolic process;GO:0034097//response to cytokine;GO:0002252;GO:0019079//viral genome replication;GO:0006952//defense response;GO:0051707//response to other organism;GO:0009154//purine ribonucleotide catabolic process;GO:0034097//response to cytokine;GO:0002252 gi|7549779|ref|NP_038634.1|/0/interferon-induced GTP-binding protein Mx2 [Mus musculus] 56758 4877.18 15.29666667 14.47 -0.080152384 Down 0.204266802 Mbnl1 muscleblind-like 1 (Drosophila) K14943|1|8e-172|608|oas:101114918|muscleblind GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003723//RNA binding;GO:0046914//transition metal ion binding "GO:0048731//system development;GO:0042692//muscle cell differentiation;GO:0043009//chordate embryonic development;GO:0000245//spliceosomal complex assembly;GO:0014706//striated muscle tissue development;GO:0035108//limb morphogenesis;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0042692//muscle cell differentiation;GO:0000245//spliceosomal complex assembly;GO:0014706//striated muscle tissue development;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0048731//system development;GO:0042692//muscle cell differentiation;GO:0043009//chordate embryonic development;GO:0000245//spliceosomal complex assembly;GO:0014706//striated muscle tissue development;GO:0035108//limb morphogenesis;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0048731//system development;GO:0042692//muscle cell differentiation;GO:0043009//chordate embryonic development;GO:0000245//spliceosomal complex assembly;GO:0014706//striated muscle tissue development;GO:0035108//limb morphogenesis;GO:0000380//alternative mRNA splicing, via spliceosome" gi|26006163|dbj|BAC41424.1|/4.50771e-165/mKIAA0428 protein [Mus musculus] 15525 4657 31.29666667 29.83666667 -0.06892264 Down 0.204247997 Hspa4 heat shock protein 4 K09489|1|0.0|1564|mmu:15525|heat shock 70kDa protein 4 GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0032550;GO:0008134//transcription factor binding GO:0001525//angiogenesis;GO:0010467//gene expression;GO:0043393//regulation of protein binding;GO:0035966//response to topologically incorrect protein;GO:0006915//apoptotic process;GO:0051100//negative regulation of binding;GO:0001932//regulation of protein phosphorylation;GO:0043623//cellular protein complex assembly;GO:0006626//protein targeting to mitochondrion gi|60360216|dbj|BAD90352.1|/0/mKIAA4025 protein [Mus musculus] 320129 6578 2.45 2.743333333 0.163148181 Up 0.204153973 Adrbk2 "adrenergic receptor kinase, beta 2" K00910|1|0.0|1408|mmu:320129|beta-adrenergic-receptor kinase [EC:2.7.11.15] GO:0005929//cilium;GO:0031674//I band;GO:0030425//dendrite;GO:0005929//cilium;GO:0031674//I band;GO:0030425//dendrite GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0008289//lipid binding;GO:0050780//dopamine receptor binding;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0008289//lipid binding;GO:0050780//dopamine receptor binding GO:0007275//multicellular organism development;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0006796//phosphate-containing compound metabolic process;GO:0042441//eye pigment metabolic process;GO:0006464//cellular protein modification process;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0007275//multicellular organism development;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0006796//phosphate-containing compound metabolic process;GO:0042441//eye pigment metabolic process;GO:0006464//cellular protein modification process;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway gi|78711830|ref|NP_796052.2|/0/beta-adrenergic receptor kinase 2 isoform 1 [Mus musculus] 209815 2452 2.453333333 2.74 0.159432628 Up 0.204153973 Tbc1d25 "TBC1 domain family, member 25" K20168|1|2e-50|203|ame:552379|TBC1 domain family member 15 - - - - 235956 1409 2.38 2.666666667 0.164075926 Up 0.204153973 Zfp825 zinc finger protein 825 K09228|1|1e-164|581|mmu:235956|KRAB domain-containing zinc finger protein - - - - 170833 2617 1.816666667 1.58 -0.201369171 Down 0.204097559 Hook2 hook microtubule tethering protein 2 K16611|1|0.0|1207|mmu:170833|protein HOOK2 - - - - 17771 2239.73 1.623333333 1.863333333 0.198926511 Up 0.204097559 Mtl5 "metallothionein-like 5, testis-specific (tesmin)" - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0048869//cellular developmental process "gi|148700988|gb|EDL32935.1|/0/mCG3887, isoform CRA_b, partial [Mus musculus]" 50702 1732 0.06 0.163333333 1.444784843 Up 0.20405995 Cfhr1 complement factor H-related 1 K04004|1|1e-68|263|oaa:100087841|complement factor H GO:0044421 - GO:0002252 gi|7656969|ref|NP_056595.1|/0/complement factor H-related 1 precursor [Mus musculus] 20192 15410 0.16 0.06 -1.415037499 Down 0.20405995 Ryr3 ryanodine receptor 3 K04963|1|0.0|9001|mmu:20192|ryanodine receptor 3 GO:0005789//endoplasmic reticulum membrane;GO:0016528//sarcoplasm;GO:0031224//intrinsic component of membrane GO:0005515//protein binding;GO:0046872//metal ion binding GO:0032026//response to magnesium ion;GO:0033198//response to ATP;GO:0006816//calcium ion transport;GO:0051592//response to calcium ion;GO:0006936//muscle contraction;GO:0051260//protein homooligomerization;GO:0031000//response to caffeine;GO:0006875//cellular metal ion homeostasis gi|983131839|ref|NP_001306085.1|/0/ryanodine receptor 3 isoform 2 [Mus musculus] 73340 4973 0.52 0.676666667 0.379933698 Up 0.20402234 Nptxr neuronal pentraxin receptor K11453|1|4e-153|545|amj:102562598|chromobox protein 6;K17495|4|1e-29|135|cge:100755877|CUB and sushi domain-containing protein GO:0031224//intrinsic component of membrane GO:0005515//protein binding;GO:0001847//opsonin receptor activity;GO:0043169//cation binding - gi|74188530|dbj|BAE28020.1|/0/unnamed protein product [Mus musculus] 20527 3973 0.513333333 0.67 0.38426515 Up 0.20402234 Slc2a3 "solute carrier family 2 (facilitated glucose transporter), member 3" "K08142|1|0.0|895|mmu:20527|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 3" GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle;GO:0044459 GO:0048029//monosaccharide binding;GO:0005355//glucose transmembrane transporter activity;GO:0051183//vitamin transporter activity;GO:0019899//enzyme binding;GO:0097367//carbohydrate derivative binding GO:0009746;GO:0006915//apoptotic process;GO:0015711//organic anion transport;GO:0015758//glucose transport "gi|261862282|ref|NP_035531.3|/0/solute carrier family 2, facilitated glucose transporter member 3 [Mus musculus]" 330817 1332 14.68 15.49666667 0.078105957 Up 0.203984731 Dhps deoxyhypusine synthase K00809|1|0.0|716|mmu:330817|deoxyhypusine synthase [EC:2.5.1.46] - "GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups" GO:0042398//cellular modified amino acid biosynthetic process;GO:0051260//protein homooligomerization;GO:0018205//peptidyl-lysine modification gi|87252720|ref|NP_001034603.1|/0/deoxyhypusine synthase [Mus musculus] 18034 3178.46 15.20666667 14.38666667 -0.079971582 Down 0.203984731 Nfkb2 "nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100" K04469|1|0.0|1535|mmu:18034|nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 GO:0031981//nuclear lumen;GO:0033256//I-kappaB/NF-kappaB complex;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0033256//I-kappaB/NF-kappaB complex;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0033256//I-kappaB/NF-kappaB complex;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0043062//extracellular structure organization;GO:0048534//hematopoietic or lymphoid organ development;GO:0002237//response to molecule of bacterial origin;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;GO:0043062//extracellular structure organization;GO:0048534//hematopoietic or lymphoid organ development;GO:0002237//response to molecule of bacterial origin;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;GO:0043062//extracellular structure organization;GO:0048534//hematopoietic or lymphoid organ development;GO:0002237//response to molecule of bacterial origin;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication;GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains" gi|9506921|ref|NP_062281.1|/0/nuclear factor NF-kappa-B p100 subunit isoform a [Mus musculus] 19334 1909 27.13666667 28.56333333 0.073920833 Up 0.203965926 Rab22a "RAB22A, member RAS oncogene family" K07891|1|1e-109|399|ocu:100350969|Ras-related protein Rab-22 GO:0016020//membrane;GO:0030139//endocytic vesicle;GO:0005856//cytoskeleton;GO:0005768//endosome GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0006996//organelle organization;GO:0016192//vesicle-mediated transport;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction gi|655897125|ref|XP_002723671.2|/1.01126e-108/PREDICTED: ras-related protein Rab-22A [Oryctolagus cuniculus] 214444 11515.58 0.753333333 0.936666667 0.314247358 Up 0.2038625 Cdk5rap2 CDK5 regulatory subunit associated protein 2 K16542|1|0.0|3259|mmu:214444|CDK5 regulatory subunit-associated protein 2 - - - - 213389 3460 0.916666667 0.74 -0.308871942 Down 0.2038625 Prdm9 PR domain containing 9 K09228|1|9e-167|590|pale:102885758|KRAB domain-containing zinc finger protein GO:0031981//nuclear lumen;GO:0043232 GO:0046914//transition metal ion binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0003677//DNA binding GO:0007131//reciprocal meiotic recombination;GO:0006366//transcription from RNA polymerase II promoter;GO:0048232//male gamete generation;GO:0034968//histone lysine methylation gi|226958682|ref|NP_659058.2|/0/histone-lysine N-methyltransferase PRDM9 [Mus musculus] 17755 11852 0.903333333 0.726666667 -0.313964717 Down 0.2038625 Map1b microtubule-associated protein 1B K10429|1|0.0|2769|mmu:17755|microtubule-associated protein 1 GO:0016020//membrane;GO:0044327//dendritic spine head;GO:0015630//microtubule cytoskeleton;GO:0043025//neuronal cell body;GO:0044444//cytoplasmic part GO:0008289//lipid binding;GO:0015631//tubulin binding "GO:0030307//positive regulation of cell growth;GO:0007409//axonogenesis;GO:0031112;GO:0034643//establishment of mitochondrion localization, microtubule-mediated;GO:0007019//microtubule depolymerization;GO:0030010//establishment of cell polarity;GO:0032386//regulation of intracellular transport" gi|568984258|ref|XP_006517611.1|/0/PREDICTED: microtubule-associated protein 1B isoform X1 [Mus musculus] 24059 4033 0.92 0.74 -0.31410859 Down 0.2038625 Slco2a1 "solute carrier organic anion transporter family, member 2a1" "K14345|1|0.0|1199|mmu:24059|solute carrier organic anion transporter family, member 2A" GO:0016021//integral component of membrane GO:0071714 GO:0044763;GO:0015908//fatty acid transport gi|110625831|ref|NP_201571.2|/0/solute carrier organic anion transporter family member 2A1 [Mus musculus] 66354 2257 27.49 28.90666667 0.072495349 Up 0.203843695 Snw1 SNW domain containing 1 K06063|1|0.0|989|mmu:66354|SNW domain-containing protein 1 GO:0071141//SMAD protein complex;GO:0005681//spliceosomal complex;GO:0008023//transcription elongation factor complex;GO:0034399//nuclear periphery;GO:0044427 GO:0051427//hormone receptor binding;GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding "GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0010720//positive regulation of cell development;GO:0009967//positive regulation of signal transduction;GO:0043921;GO:0031062//positive regulation of histone methylation;GO:0030522//intracellular receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0000398//mRNA splicing, via spliceosome;GO:0032526//response to retinoic acid" "gi|148671009|gb|EDL02956.1|/0/SNW domain containing 1, partial [Mus musculus]" 321019 2942 0.15 0.266666667 0.830074999 Up 0.203834292 Gpr183 G protein-coupled receptor 183 K04305|1|0.0|670|mmu:321019|Epstein-Barr virus induced gene 2 GO:0016021//integral component of membrane GO:0032934//sterol binding;GO:0001608 GO:0002312//B cell activation involved in immune response;GO:0043410//positive regulation of MAPK cascade;GO:0030888//regulation of B cell proliferation;GO:0035588 gi|88853593|ref|NP_898852.2|/0/G-protein coupled receptor 183 [Mus musculus] 73824 407 5.626666667 6.056666667 0.106243516 Up 0.20382489 Snhg6 small nucleolar RNA host gene 6 - - - - - 15366 3914 2.006666667 2.266666667 0.175771259 Up 0.203768476 Hmmr hyaluronan mediated motility receptor (RHAMM) K06267|1|0.0|1336|mmu:15366|hyaluronan-mediated motility receptor GO:0044424 - GO:0044763 gi|226693396|ref|NP_038580.2|/0/hyaluronan mediated motility receptor [Mus musculus] 66643 3124 2.04 2.303333333 0.175154058 Up 0.203768476 Lix1 limb and CNS expressed 1 K16673|1|5e-80|302|aam:106484218|LIX1-like protein - - - - 20671 3382.61 6.686666667 7.18 0.102696644 Up 0.203749671 Sox17 SRY (sex determining region Y)-box 17 K04495|1|0.0|690|mmu:20671|transcription factor SOX17 (SOX group F) GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle "GO:0003712//transcription cofactor activity;GO:0005515//protein binding;GO:0000975//regulatory region DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0005515//protein binding;GO:0000975//regulatory region DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0005515//protein binding;GO:0000975//regulatory region DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0005515//protein binding;GO:0000975//regulatory region DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0005515//protein binding;GO:0000975//regulatory region DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding" GO:0003160//endocardium morphogenesis;GO:0007501//mesodermal cell fate specification;GO:0001709//cell fate determination;GO:0009952//anterior/posterior pattern specification;GO:0048232//male gamete generation;GO:0016049//cell growth;GO:0001667//ameboidal-type cell migration;GO:0003306//Wnt signaling pathway involved in heart development;GO:0042659//regulation of cell fate specification;GO:0000904//cell morphogenesis involved in differentiation;GO:0042127//regulation of cell proliferation;GO:0009896;GO:0030178//negative regulation of Wnt signaling pathway;GO:0051302//regulation of cell division;GO:0006366//transcription from RNA polymerase II promoter;GO:0003143//embryonic heart tube morphogenesis;GO:0007440//foregut morphogenesis;GO:0001714//endodermal cell fate specification;GO:0007519//skeletal muscle tissue development;GO:0001655//urogenital system development;GO:0031647//regulation of protein stability;GO:0003160//endocardium morphogenesis;GO:0007501//mesodermal cell fate specification;GO:0001709//cell fate determination;GO:0009952//anterior/posterior pattern specification;GO:0048232//male gamete generation;GO:0016049//cell growth;GO:0001667//ameboidal-type cell migration;GO:0003306//Wnt signaling pathway involved in heart development;GO:0042659//regulation of cell fate specification;GO:0000904//cell morphogenesis involved in differentiation;GO:0042127//regulation of cell proliferation;GO:0009896;GO:0030178//negative regulation of Wnt signaling pathway;GO:0051302//regulation of cell division;GO:0006366//transcription from RNA polymerase II promoter;GO:0003143//embryonic heart tube morphogenesis;GO:0007440//foregut morphogenesis;GO:0001714//endodermal cell fate specification;GO:0007519//skeletal muscle tissue development;GO:0001655//urogenital system development;GO:0031647//regulation of protein stability;GO:0003160//endocardium morphogenesis;GO:0007501//mesodermal cell fate specification;GO:0001709//cell fate determination;GO:0009952//anterior/posterior pattern specification;GO:0048232//male gamete generation;GO:0016049//cell growth;GO:0001667//ameboidal-type cell migration;GO:0003306//Wnt signaling pathway involved in heart development;GO:0042659//regulation of cell fate specification;GO:0000904//cell morphogenesis involved in differentiation;GO:0042127//regulation of cell proliferation;GO:0009896;GO:0030178//negative regulation of Wnt signaling pathway;GO:0051302//regulation of cell division;GO:0006366//transcription from RNA polymerase II promoter;GO:0003143//embryonic heart tube morphogenesis;GO:0007440//foregut morphogenesis;GO:0001714//endodermal cell fate specification;GO:0007519//skeletal muscle tissue development;GO:0001655//urogenital system development;GO:0031647//regulation of protein stability;GO:0003160//endocardium morphogenesis;GO:0007501//mesodermal cell fate specification;GO:0001709//cell fate determination;GO:0009952//anterior/posterior pattern specification;GO:0048232//male gamete generation;GO:0016049//cell growth;GO:0001667//ameboidal-type cell migration;GO:0003306//Wnt signaling pathway involved in heart development;GO:0042659//regulation of cell fate specification;GO:0000904//cell morphogenesis involved in differentiation;GO:0042127//regulation of cell proliferation;GO:0009896;GO:0030178//negative regulation of Wnt signaling pathway;GO:0051302//regulation of cell division;GO:0006366//transcription from RNA polymerase II promoter;GO:0003143//embryonic heart tube morphogenesis;GO:0007440//foregut morphogenesis;GO:0001714//endodermal cell fate specification;GO:0007519//skeletal muscle tissue development;GO:0001655//urogenital system development;GO:0031647//regulation of protein stability;GO:0003160//endocardium morphogenesis;GO:0007501//mesodermal cell fate specification;GO:0001709//cell fate determination;GO:0009952//anterior/posterior pattern specification;GO:0048232//male gamete generation;GO:0016049//cell growth;GO:0001667//ameboidal-type cell migration;GO:0003306//Wnt signaling pathway involved in heart development;GO:0042659//regulation of cell fate specification;GO:0000904//cell morphogenesis involved in differentiation;GO:0042127//regulation of cell proliferation;GO:0009896;GO:0030178//negative regulation of Wnt signaling pathway;GO:0051302//regulation of cell division;GO:0006366//transcription from RNA polymerase II promoter;GO:0003143//embryonic heart tube morphogenesis;GO:0007440//foregut morphogenesis;GO:0001714//endodermal cell fate specification;GO:0007519//skeletal muscle tissue development;GO:0001655//urogenital system development;GO:0031647//regulation of protein stability "gi|148682294|gb|EDL14241.1|/0/SRY-box containing gene 17, isoform CRA_b, partial [Mus musculus]" 107303348 3895 1.556666667 1.34 -0.216227049 Down 0.203740269 Setdb2-phf11c Setdb2-Phf11c readthrough K18494|1|0.0|1999|mmu:107303348|histone-lysine N-methyltransferase SETDB2 [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0046914//transition metal ion binding;GO:0018024//histone-lysine N-methyltransferase activity GO:0034968//histone lysine methylation;GO:0000087//mitotic M phase;GO:0032502//developmental process gi|164430329|gb|ABY55490.1|/0/SET domain bifurcated protein 2-Phf11-1 fusion protein [Mus musculus] 16324 4255 1.323333333 1.543333333 0.221873186 Up 0.203740269 Inhbb inhibin beta-B "K04667|1|0.0|687|rno:25196|inhibin, beta" GO:0044444//cytoplasmic part GO:0005102//receptor binding;GO:0042802//identical protein binding GO:0032868//response to insulin;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0032277//negative regulation of gonadotropin secretion;GO:0008585//female gonad development;GO:0006915//apoptotic process;GO:0050796//regulation of insulin secretion;GO:0007281//germ cell development;GO:0032278;GO:0033554//cellular response to stress;GO:0030728//ovulation;GO:0032870//cellular response to hormone stimulus;GO:0042036//negative regulation of cytokine biosynthetic process gi|74315992|ref|NP_032407.1|/0/inhibin beta B chain precursor [Mus musculus] 99167 3454 4.093333333 3.746666667 -0.127668525 Down 0.203702659 Ssx2ip "synovial sarcoma, X breakpoint 2 interacting protein" "K06085|1|0.0|1149|mmu:99167|synovial sarcoma, X breakpoint 2 interacting protein" GO:0005911//cell-cell junction;GO:0044464;GO:0032991//macromolecular complex;GO:0005911//cell-cell junction;GO:0044464;GO:0032991//macromolecular complex;GO:0005911//cell-cell junction;GO:0044464;GO:0032991//macromolecular complex GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0016601//Rac protein signal transduction;GO:0007010//cytoskeleton organization;GO:0040012//regulation of locomotion;GO:0022610;GO:0016601//Rac protein signal transduction;GO:0007010//cytoskeleton organization;GO:0040012//regulation of locomotion;GO:0022610;GO:0016601//Rac protein signal transduction;GO:0007010//cytoskeleton organization;GO:0040012//regulation of locomotion;GO:0022610 gi|50510713|dbj|BAD32342.1|/0/mKIAA0923 protein [Mus musculus] 69192 3405 10.04666667 10.65666667 0.085039327 Up 0.20362744 Dhx16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 K12813|1|0.0|1755|mmu:69192|pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:3.6.4.13] GO:0031981//nuclear lumen "GO:0032550;GO:0042623//ATPase activity, coupled" GO:0006396//RNA processing "gi|148691295|gb|EDL23242.1|/0/DEAH (Asp-Glu-Ala-His) box polypeptide 16, isoform CRA_a [Mus musculus]" 193670 3372.86 10.51 9.903333333 -0.085776565 Down 0.20362744 Rnf185 ring finger protein 185 K10666|1|3e-42|176|xtr:448093|E3 ubiquitin-protein ligase RNF5 [EC:2.3.2.27] GO:0016020//membrane;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0016020//membrane GO:0046872//metal ion binding GO:0044237//cellular metabolic process gi|31981757|ref|NP_663330.2|/3.81506e-86/E3 ubiquitin-protein ligase RNF185 isoform 1 [Mus musculus] 22067 8502 0.156666667 0.06 -1.38466385 Down 0.203608635 Trpc5 "transient receptor potential cation channel, subfamily C, member 5" K04968|1|0.0|1831|mmu:22067|transient receptor potential cation channel subfamily C member 5 - - - - 624855 2397 0.06 0.156666667 1.38466385 Up 0.203608635 Cks1brt "CDC28 protein kinase 1b, retrogene" K02219|1|2e-44|183|cge:103160037|cyclin-dependent kinase regulatory subunit CKS1 GO:0031981//nuclear lumen "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005488//binding;GO:0019887//protein kinase regulator activity" GO:0051726//regulation of cell cycle;GO:0044772//mitotic cell cycle phase transition;GO:0051320;GO:0006796//phosphate-containing compound metabolic process;GO:0051318 gi|148679055|gb|EDL11002.1|/3.03007e-52/mCG132387 [Mus musculus] 17189 1080.55 13726.30333 14357.28333 0.064839648 Up 0.203571026 Mb myoglobin K14946|1|2e-47|192|aam:106488252|RNA binding protein fox-1;K13826|2|6e-11|70.9|ecb:100065056|hemoglobin subunit zeta;K13825|4|5e-10|67.8|ecb:100068926|hemoglobin subunit epsilon - GO:0046906//tetrapyrrole binding;GO:0022892//substrate-specific transporter activity;GO:0046914//transition metal ion binding;GO:0046906//tetrapyrrole binding;GO:0022892//substrate-specific transporter activity;GO:0046914//transition metal ion binding;GO:0046906//tetrapyrrole binding;GO:0022892//substrate-specific transporter activity;GO:0046914//transition metal ion binding GO:0015669;GO:0000302//response to reactive oxygen species;GO:0009719;GO:0014721;GO:0030218//erythrocyte differentiation;GO:0045444//fat cell differentiation;GO:0015669;GO:0000302//response to reactive oxygen species;GO:0009719;GO:0014721;GO:0030218//erythrocyte differentiation;GO:0045444//fat cell differentiation;GO:0015669;GO:0000302//response to reactive oxygen species;GO:0009719;GO:0014721;GO:0030218//erythrocyte differentiation;GO:0045444//fat cell differentiation gi|21359820|ref|NP_038621.2|/1.60251e-82/myoglobin [Mus musculus] 192216 4082 2.486666667 2.216666667 -0.16582129 Down 0.203552221 Tmem47 transmembrane protein 47 K10136|1|5e-13|80.1|cmy:102937173|TP53 apoptosis effector GO:0031224//intrinsic component of membrane;GO:0030054//cell junction - - "gi|148697222|gb|EDL29169.1|/1.1831e-102/transmembrane protein 47, isoform CRA_a, partial [Mus musculus]" 107823 7125.49 2.2 2.466666667 0.165059246 Up 0.203552221 Whsc1 Wolf-Hirschhorn syndrome candidate 1 (human) K11424|1|0.0|1155|mmu:107823|histone-lysine N-methyltransferase NSD2 [EC:2.1.1.43] - - - gi|295424169|ref|NP_001171355.1|/0/histone-lysine N-methyltransferase NSD2 isoform 3 [Mus musculus] 17150 1084 2.36 2.093333333 -0.172984801 Down 0.203552221 Mfap2 microfibrillar-associated protein 2 K13526|1|2e-77|291|pps:100993572|cation-transporting ATPase 13A2 [EC:3.6.3.-];K10989|3|3e-17|91.7|tgu:100229705|activation-induced cytidine deaminase [EC:3.5.4.38] GO:0031012//extracellular matrix;GO:0031012//extracellular matrix GO:0032403//protein complex binding;GO:0032403//protein complex binding GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048646//anatomical structure formation involved in morphogenesis gi|568930715|ref|XP_006538675.1|/9.31383e-94/PREDICTED: microfibrillar-associated protein 2 isoform X1 [Mus musculus] 11739 1142 4351.8 4524.23 0.056060019 Up 0.203542818 Slc25a4 "solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4" "K05863|1|4e-162|573|mmu:11739|solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31" GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane;GO:0019866//organelle inner membrane GO:0005515//protein binding;GO:0015297//antiporter activity GO:0006915//apoptotic process;GO:0032411//positive regulation of transporter activity;GO:0070265//necrotic cell death;GO:0051933 gi|148747424|ref|NP_031476.3|/3.27837e-161/ADP/ATP translocase 1 [Mus musculus] 217578 6179 1.503333333 1.736666667 0.208155939 Up 0.203486404 Baz1a bromodomain adjacent to zinc finger domain 1A K11655|1|0.0|2521|mmu:217578|bromodomain adjacent to zinc finger domain protein 1A - - - gi|189339272|ref|NP_038843.2|/0/bromodomain adjacent to zinc finger domain protein 1A [Mus musculus] 12865 393 1723.48 1650.376667 -0.062529228 Down 0.203458197 Cox7a1 cytochrome c oxidase subunit VIIa 1 K02270|1|2e-40|165|mmu:12865|cytochrome c oxidase subunit 7a GO:0005743//mitochondrial inner membrane;GO:0031224//intrinsic component of membrane GO:0015002//heme-copper terminal oxidase activity GO:0006818//hydrogen transport;GO:0006811//ion transport;GO:0044710 "gi|6753504|ref|NP_034074.1|/2.3168e-39/cytochrome c oxidase subunit 7A1, mitochondrial precursor [Mus musculus]" 57390 850 0.066666667 0.166666667 1.321928095 Up 0.20342999 Psors1c2 psoriasis susceptibility 1 candidate 2 (human) - - - - gi|5731131|gb|AAD48782.1|AF159090_1/1.38804e-53/MHC psoriasis candidate protein [Mus musculus] 58237 865 0.063333333 0.16 1.337034987 Up 0.20342999 Nkain4 Na+/K+ transporting ATPase interacting 4 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|213513245|ref|NP_001135405.1|/3.86706e-91/sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 isoform 2 precursor [Mus musculus] 74364 2735 0.286666667 0.163333333 -0.811554911 Down 0.20342999 4931431C16Rik RIKEN cDNA 4931431C16 gene K00232|1|1e-19|101|mmu:80911|acyl-CoA oxidase [EC:1.3.3.6] - - - - 68423 2155 0.46 0.32 -0.523561956 Down 0.20339238 Ankrd13d "ankyrin repeat domain 13 family, member D" K05766|1|0.0|915|ssc:100515297|protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48];K16943|2|2e-161|572|tca:655956|septin 4;K00910|3|6e-54|214|apla:101801089|beta-adrenergic-receptor kinase [EC:2.7.11.15] - - - gi|884909765|ref|XP_013006270.1|/0/PREDICTED: ankyrin repeat domain-containing protein 13D isoform X2 [Cavia porcellus] 654309 1170 0.32 0.46 0.523561956 Up 0.20339238 Nrp neural regeneration protein K10765|1|8e-20|100|mmu:211064|alkylated DNA repair protein alkB homolog 1 [EC:1.14.11.- 4.2.99.18] GO:0000790//nuclear chromatin "GO:0016835//carbon-oxygen lyase activity;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0005506//iron ion binding" GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0040007//growth;GO:0016070//RNA metabolic process;GO:0030030//cell projection organization;GO:0048869//cellular developmental process;GO:0006935//chemotaxis;GO:0035510;GO:0044767//single-organism developmental process;GO:0055114//oxidation-reduction process;GO:0016477//cell migration;GO:0006281//DNA repair gi|62909989|ref|NP_001013390.1|/4.43458e-68/neural regeneration protein [Mus musculus] 195018 11150 3.006666667 2.706666667 -0.151647706 Down 0.203335966 Zzef1 "zinc finger, ZZ-type with EF hand domain 1" K11970|1|4e-20|105|acs:100561878|p53-associated parkin-like cytoplasmic protein;K10595|2|7e-20|104|crg:105319253|E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26];K12233|4|3e-19|102|bfo:BRAFLDRAFT_276868|E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26] - GO:0046914//transition metal ion binding - gi|113865905|ref|NP_001039001.1|/0/zinc finger ZZ-type and EF-hand domain-containing protein 1 [Mus musculus] 231207 6815.36 2.946666667 2.65 -0.153091509 Down 0.203335966 Cpeb2 cytoplasmic polyadenylation element binding protein 2 K02602|1|0.0|1237|mmu:231207|cytoplasmic polyadenylation element-binding protein GO:0030529//intracellular ribonucleoprotein complex GO:0003727//single-stranded RNA binding GO:0006414//translational elongation gi|293651586|ref|NP_787951.2|/0/cytoplasmic polyadenylation element-binding protein 2 isoform 1 [Mus musculus] 101095 5222 3.1 2.8 -0.146841388 Down 0.203335966 Zfp282 zinc finger protein 282 K09228|1|0.0|1118|mmu:101095|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|114158689|ref|NP_666287.3|/0/zinc finger protein 282 [Mus musculus] 67030 1798 2.666666667 2.963333333 0.152183419 Up 0.203335966 Fancl "Fanconi anemia, complementation group L" K10606|1|0.0|723|mmu:67030|E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0012505//endomembrane system GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0016567//protein ubiquitination;GO:0019953//sexual reproduction;GO:0008283//cell proliferation;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0016567//protein ubiquitination;GO:0019953//sexual reproduction;GO:0008283//cell proliferation;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0016567//protein ubiquitination;GO:0019953//sexual reproduction;GO:0008283//cell proliferation gi|472235270|ref|NP_001264202.1|/0/E3 ubiquitin-protein ligase FANCL isoform 2 [Mus musculus] 22190 2424 1127.2 1078.463333 -0.06376639 Down 0.203307759 Ubc ubiquitin C K08770|1|0.0|1425|mmu:22190|ubiquitin C GO:0043231//intracellular membrane-bounded organelle - GO:0019941//modification-dependent protein catabolic process;GO:0019725//cellular homeostasis gi|157671923|ref|NP_062613.3|/0/polyubiquitin-C [Mus musculus] 57423 496 1090.043333 1138.18 0.062343245 Up 0.203307759 Atp5j2 "ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2" K02130|1|6e-45|181|mmu:57423|F-type H+-transporting ATPase subunit f "GO:0005743//mitochondrial inner membrane;GO:0031224//intrinsic component of membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain" GO:0017111//nucleoside-triphosphatase activity GO:0006818//hydrogen transport;GO:0009152//purine ribonucleotide biosynthetic process;GO:0009154//purine ribonucleotide catabolic process "gi|149034885|gb|EDL89605.1|/1.42353e-52/rCG42655, isoform CRA_b [Rattus norvegicus]" 70233 3368.51 13.21 14.00666667 0.084483195 Up 0.203288954 Cd2bp2 CD2 antigen (cytoplasmic tail) binding protein 2 K13099|1|8e-168|593|mmu:70233|CD2 antigen cytoplasmic tail-binding protein 2 GO:0030532//small nuclear ribonucleoprotein complex;GO:0016604//nuclear body;GO:0030532//small nuclear ribonucleoprotein complex;GO:0016604//nuclear body;GO:0030532//small nuclear ribonucleoprotein complex;GO:0016604//nuclear body;GO:0030532//small nuclear ribonucleoprotein complex;GO:0016604//nuclear body GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0010921//regulation of phosphatase activity;GO:0010921//regulation of phosphatase activity;GO:0010921//regulation of phosphatase activity;GO:0010921//regulation of phosphatase activity "gi|148685558|gb|EDL17505.1|/0/mCG134114, isoform CRA_b, partial [Mus musculus]" 192159 7500 29.62 28.24 -0.068831552 Down 0.203213735 Prpf8 pre-mRNA processing factor 8 K12856|1|0.0|4666|rno:287530|pre-mRNA-processing factor 8 GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex;GO:0016604//nuclear body GO:0003676//nucleic acid binding GO:0000377 gi|521020961|gb|EPQ02749.1|/0/Pre-mRNA-processing-splicing factor 8 [Myotis brandtii] 14797 1487.78 904.9166667 942.99 0.059457531 Up 0.20319493 Aes amino-terminal enhancer of split K04497|1|7e-45|184|dre:30206|groucho GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0005488//binding;GO:0003712//transcription cofactor activity;GO:0005488//binding;GO:0003712//transcription cofactor activity;GO:0005488//binding GO:0009653//anatomical structure morphogenesis;GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0043393//regulation of protein binding;GO:0034097//response to cytokine;GO:0030178//negative regulation of Wnt signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0009653//anatomical structure morphogenesis;GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0043393//regulation of protein binding;GO:0034097//response to cytokine;GO:0030178//negative regulation of Wnt signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0009653//anatomical structure morphogenesis;GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0043393//regulation of protein binding;GO:0034097//response to cytokine;GO:0030178//negative regulation of Wnt signaling pathway;GO:0043065//positive regulation of apoptotic process gi|443609482|ref|NP_001263217.1|/2.61682e-82/amino-terminal enhancer of split isoform 2 [Mus musculus] 272347 3358.86 0.663333333 0.833333333 0.329159664 Up 0.203138516 Zfp398 zinc finger protein 398 K09228|1|0.0|947|mmu:272347|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0043169//cation binding "GO:0006351//transcription, DNA-templated" gi|74206956|dbj|BAE33275.1|/0/unnamed protein product [Mus musculus] 18768 5455.79 0.32 0.456666667 0.513069582 Up 0.203044492 Pkib "protein kinase inhibitor beta, cAMP dependent, testis specific" - - "GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0001933//negative regulation of protein phosphorylation;GO:0001933//negative regulation of protein phosphorylation;GO:0001933//negative regulation of protein phosphorylation;GO:0001933//negative regulation of protein phosphorylation;GO:0001933//negative regulation of protein phosphorylation;GO:0001933//negative regulation of protein phosphorylation gi|84794591|ref|NP_032889.3|/2.38404e-34/cAMP-dependent protein kinase inhibitor beta isoform 1 [Mus musculus] 210094 2567 0.473333333 0.333333333 -0.50589093 Down 0.203044492 Iglon5 IgLON family member 5 K06773|1|4e-164|581|mmu:210094|opioid binding protein/cell adhesion molecule-like - - - gi|257096063|ref|NP_001157990.1|/3.52337e-163/igLON family member 5 precursor [Mus musculus] 69781 616 0.336666667 0.48 0.511713519 Up 0.203044492 1600010M07Rik RIKEN cDNA 1600010M07 gene - - - - - 14419 699 0.076666667 0.01 -2.938599455 Down 0.203016285 Gal galanin K05244|1|1e-55|218|mmu:14419|galanin "GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0005102//receptor binding GO:0006952//defense response;GO:0048731//system development;GO:0048545//response to steroid hormone;GO:0002682//regulation of immune system process;GO:0008211//glucocorticoid metabolic process;GO:0006915//apoptotic process;GO:0043434//response to peptide hormone;GO:0032945//negative regulation of mononuclear cell proliferation;GO:0007610//behavior;GO:0007186//G-protein coupled receptor signaling pathway "gi|148700992|gb|EDL32939.1|/9.73452e-65/galanin, isoform CRA_a [Mus musculus]" 67651 735 0.076666667 0.01 -2.938599455 Down 0.203016285 4930527F14Rik RIKEN cDNA 4930527F14 gene - - - - - 73815 767 0.076666667 0.01 -2.938599455 Down 0.203016285 4930404H11Rik RIKEN cDNA 4930404H11 gene - - - - gi|148704600|gb|EDL36547.1|/3.18896e-40/mCG1041734 [Mus musculus] 100041033 730 0.076666667 0.01 -2.938599455 Down 0.203016285 Gm20858 Sycp3 like Y-linked pseudogene K19528|1|3e-23|102|lve:103085291|synaptonemal complex protein 3 - - - gi|237513008|ref|NP_963288.2|/7.89968e-89/Sycp3 like Y-linked [Mus musculus] 100040999 628 0.01 0.076666667 2.938599455 Up 0.203016285 Gm3086 RuvB-like protein 1 pseudogene K04499|1|1e-38|123|mcf:102116128|RuvB-like protein 1 (pontin 52) GO:0044665//MLL1/2 complex;GO:0043189//H4/H2A histone acetyltransferase complex;GO:0000790//nuclear chromatin GO:1901363//heterocyclic compound binding;GO:0036094//small molecule binding;GO:0097159//organic cyclic compound binding;GO:0016887//ATPase activity;GO:0003678//DNA helicase activity GO:0006366//transcription from RNA polymerase II promoter;GO:0048232//male gamete generation;GO:0033554//cellular response to stress;GO:0043486//histone exchange;GO:0016573//histone acetylation;GO:0007049//cell cycle;GO:0032392//DNA geometric change gi|982280892|ref|XP_015286266.1|/8.33145e-38/PREDICTED: ruvB-like 1 [Macaca fascicularis] 434800 703 0.01 0.076666667 2.938599455 Up 0.203016285 Smim9 small integral membrane protein 9 - GO:0031224//intrinsic component of membrane - - gi|85702107|ref|NP_001028958.1|/4.54107e-64/small integral membrane protein 9 precursor [Mus musculus] 66338 723 0.01 0.076666667 2.938599455 Up 0.203016285 Cdrt4 CMT1A duplicated region transcript 4 - - - - gi|13384920|ref|NP_079772.1|/2.42337e-92/CMT1A duplicated region transcript 4 protein homolog [Mus musculus] 208080 1381 0.076666667 0.01 -2.938599455 Down 0.203016285 Ubap1l ubiquitin-associated protein 1-like K11292|1|2e-08|62.8|myb:102262331|transcription elongation factor SPT6 - - - gi|162287229|ref|NP_001104615.1|/0/ubiquitin-associated protein 1-like [Mus musculus] 75526 755 0.076666667 0.01 -2.938599455 Down 0.203016285 Eppin epididymal peptidase inhibitor K12864|1|9e-17|89.4|clv:102090334|beta-catenin-like protein 1;K03909|2|4e-12|73.9|crg:105330341|tissue factor pathway inhibitor - - - - 100043885 1178 0.01 0.076666667 2.938599455 Up 0.203016285 Gm4710 predicted gene 4710 - - - - gi|148706503|gb|EDL38450.1|/7.45498e-31/mCG1039549 [Mus musculus] 58217 3025 0.01 0.076666667 2.938599455 Up 0.203016285 Trem1 triggering receptor expressed on myeloid cells 1 K14362|1|4e-111|405|mmu:58217|triggering receptor expressed on myeloid cells 1 GO:0031224//intrinsic component of membrane - - gi|10946760|ref|NP_067381.1|/3.19648e-110/triggering receptor expressed on myeloid cells 1 precursor [Mus musculus] 16642 707 0.076666667 0.01 -2.938599455 Down 0.203016285 Klrc2 "killer cell lectin-like receptor subfamily C, member 2" K06541|1|8e-121|434|mmu:16642|killer cell lectin-like receptor subfamily C GO:0009986//cell surface;GO:0009986//cell surface GO:0005488//binding - "gi|148886722|ref|NP_001092139.1|/1.77096e-124/killer cell lectin-like receptor subfamily C, member 2 isoform 2 [Mus musculus]" 74928 723 0.076666667 0.01 -2.938599455 Down 0.203016285 4930467K11Rik RIKEN cDNA 4930467K11 gene - - - - - 244551 730 0.01 0.076666667 2.938599455 Up 0.203016285 Nanos3 nanos homolog 3 (Drosophila) K18761|1|2e-72|273|mmu:244551|protein nanos 3 GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0006412//translation;GO:0048869//cellular developmental process;GO:0007049//cell cycle;GO:0006915//apoptotic process;GO:0007292//female gamete generation;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction gi|34610217|ref|NP_918948.1|/1.85867e-71/nanos homolog 3 [Mus musculus] 545136 3187 0.076666667 0.01 -2.938599455 Down 0.203016285 Fam186b "family with sequence similarity 186, member B" - - - - gi|124486943|ref|NP_001074723.1|/0/protein FAM186B [Mus musculus] 15403 699 0.01 0.076666667 2.938599455 Up 0.203016285 Hoxa6 homeobox A6 K09306|1|3e-127|456|mmu:15403|homeobox protein HoxA/B/C6 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0003002//regionalization;GO:0001501//skeletal system development;GO:0048562//embryonic organ morphogenesis;GO:0006351//transcription, DNA-templated" gi|27544943|ref|NP_034584.1|/2.42074e-126/homeobox protein Hox-A6 [Mus musculus] 208613 733 0.01 0.076666667 2.938599455 Up 0.203016285 Tmem212 transmembrane protein 212 - GO:0031224//intrinsic component of membrane - - gi|26343237|dbj|BAC35275.1|/1.42012e-111/unnamed protein product [Mus musculus] 239659 717 0.076666667 0.01 -2.938599455 Down 0.203016285 C1ql4 "complement component 1, q subcomponent-like 4" K18744|1|3e-18|94.4|ola:101161935|caprin-2;K07296|5|4e-17|90.5|gga:404536|adiponectin GO:0005578//proteinaceous extracellular matrix - - gi|71725391|ref|NP_001019873.1|/1.71569e-98/complement C1q-like protein 4 precursor [Mus musculus] 77855 1269 0.076666667 0.01 -2.938599455 Down 0.203016285 D730045A05Rik RIKEN cDNA D730045A05 gene - - - - - 77001 726 0.076666667 0.01 -2.938599455 Down 0.203016285 1700110I07Rik RIKEN cDNA 1700110I07 gene - - - - - 16904 1087.45 4.396666667 4.78 0.120600459 Up 0.203006883 Gzmm granzyme M (lymphocyte met-ase 1) K08649|1|5e-111|403|mmu:16904|granzyme M [EC:3.4.21.-] - GO:0005488//binding;GO:0004175//endopeptidase activity;GO:0005488//binding;GO:0004175//endopeptidase activity;GO:0005488//binding;GO:0004175//endopeptidase activity;GO:0005488//binding;GO:0004175//endopeptidase activity GO:0006952//defense response;GO:0012501//programmed cell death;GO:0019538//protein metabolic process;GO:0006952//defense response;GO:0012501//programmed cell death;GO:0019538//protein metabolic process;GO:0006952//defense response;GO:0012501//programmed cell death;GO:0019538//protein metabolic process;GO:0006952//defense response;GO:0012501//programmed cell death;GO:0019538//protein metabolic process "gi|148699729|gb|EDL31676.1|/7.65063e-115/granzyme M (lymphocyte met-ase 1), isoform CRA_a, partial [Mus musculus]" 22689 3582.63 4.876666667 4.5 -0.115970362 Down 0.203006883 Zfp27 zinc finger protein 27 K09228|1|0.0|1744|mmu:22689|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148692104|gb|EDL24051.1|/0/zinc finger protein 27, partial [Mus musculus]" 16523 2188 27.39 26.03333333 -0.073289218 Down 0.202969273 Kcnj8 "potassium inwardly-rectifying channel, subfamily J, member 8" K05001|1|0.0|748|mmu:16523|potassium inwardly-rectifying channel subfamily J member 8 - - - gi|6680534|ref|NP_032454.1|/0/ATP-sensitive inward rectifier potassium channel 8 [Mus musculus] 23796 3573 9.973333333 9.37 -0.090026722 Down 0.202941066 Aplnr apelin receptor K04174|1|0.0|670|mmu:23796|apelin receptor GO:0016021//integral component of membrane GO:0033218//amide binding;GO:0004888//transmembrane signaling receptor activity GO:0044707;GO:0007166//cell surface receptor signaling pathway gi|6753014|ref|NP_035914.1|/0/apelin receptor [Mus musculus] 67236 2029 9.01 9.61 0.093009325 Up 0.202941066 Cinp cyclin-dependent kinase 2 interacting protein - GO:0043231//intracellular membrane-bounded organelle - GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0044763 gi|21361248|ref|NP_080324.1|/4.60836e-99/cyclin-dependent kinase 2-interacting protein isoform 1 [Mus musculus] 75062 1710 9.58 10.18333333 0.088112318 Up 0.202941066 Sf3a3 "splicing factor 3a, subunit 3" K12827|1|0.0|971|cge:100751561|splicing factor 3A subunit 3 GO:0005681//spliceosomal complex;GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0006376//mRNA splice site selection "gi|148698409|gb|EDL30356.1|/0/mCG17252, isoform CRA_b, partial [Mus musculus]" 75691 3552 0.91 1.096666667 0.269186633 Up 0.202884652 Anks6 ankyrin repeat and sterile alpha motif domain containing 6 K16726|1|9e-38|162|cqu:CpipJ_CPIJ002710|ankyrin repeat domain-containing protein 17 GO:0044424 GO:0042802//identical protein binding - gi|67906181|ref|NP_001019307.1|/0/ankyrin repeat and SAM domain-containing protein 6 [Mus musculus] 212679 2882 3.233333333 3.556666667 0.137503524 Up 0.202875249 Mars2 methionine-tRNA synthetase 2 (mitochondrial) K01874|1|0.0|1211|mmu:212679|methionyl-tRNA synthetase [EC:6.1.1.10] GO:0044429 GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation gi|26335385|dbj|BAC31393.1|/0/unnamed protein product [Mus musculus] 109700 5984 3.36 3.043333333 -0.142808874 Down 0.202875249 Itga1 integrin alpha 1 K06480|1|0.0|2285|mmu:109700|integrin alpha 1 GO:0030141//secretory granule;GO:0009986//cell surface;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0005887//integral component of plasma membrane GO:0043169//cation binding;GO:0005102//receptor binding;GO:0046983//protein dimerization activity GO:0022610;GO:0031175//neuron projection development;GO:0043065//positive regulation of apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0030595//leukocyte chemotaxis;GO:0050880//regulation of blood vessel size gi|153791389|ref|NP_001028400.2|/0/integrin alpha-1 precursor [Mus musculus] 319870 2476 3.06 3.383333333 0.144913669 Up 0.202875249 9330136K24Rik RIKEN cDNA 9330136K24 gene K09228|1|1e-34|151|mmu:22709|KRAB domain-containing zinc finger protein - - - - 319472 3103 3.356666667 3.04 -0.142957954 Down 0.202875249 9330158H04Rik RIKEN cDNA 9330158H04 gene - - - - - 68375 739 543.4533333 520.72 -0.061648336 Down 0.202856444 Ndufa8 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8" K03952|1|7e-86|318|mmu:68375|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8 GO:0005746//mitochondrial respiratory chain - GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy "gi|148676718|gb|EDL08665.1|/3.54729e-94/NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8 [Mus musculus]" 74675 3238 0.103333333 0.02 -2.36923381 Down 0.202790628 Ptchd3 patched domain containing 3 K12385|1|3e-55|219|aec:105150006|Niemann-Pick C1 protein GO:0031224//intrinsic component of membrane - - gi|226442984|ref|NP_083325.1|/0/patched domain-containing protein 3 [Mus musculus] 22608 2191 434.94 454.42 0.063209938 Up 0.202715409 Ybx1 Y box protein 1 K09276|1|2e-103|355|chx:102184870|Y-box-binding protein 1 GO:0043005//neuron projection;GO:0044444//cytoplasmic part;GO:0005634//nucleus;GO:0030529//intracellular ribonucleoprotein complex GO:0005515//protein binding;GO:0003723//RNA binding;GO:0043566//structure-specific DNA binding GO:0008286//insulin receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0010468//regulation of gene expression;GO:0006915//apoptotic process;GO:0051146//striated muscle cell differentiation;GO:0043009//chordate embryonic development gi|823419836|ref|XP_012420023.1|/1.41591e-109/PREDICTED: nuclease-sensitive element-binding protein 1 [Odobenus rosmarus divergens] 74034 2951 1.053333333 1.25 0.246966037 Up 0.202715409 4632404H12Rik RIKEN cDNA 4632404H12 gene K10591|1|9e-06|55.5|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] - - - - 50720 3343 1.036666667 1.236666667 0.254504606 Up 0.202715409 Sacs sacsin K17592|1|0.0|1489|mmu:50720|sacsin GO:0043231//intracellular membrane-bounded organelle GO:0032403//protein complex binding;GO:0031072//heat shock protein binding GO:0051129 gi|85677482|ref|NP_766397.2|/0/sacsin [Mus musculus] 15364 4226 1.083333333 1.286666667 0.248161129 Up 0.202715409 Hmga2 high mobility group AT-hook 2 K09283|1|3e-26|124|mmu:15364|high mobility group AT-hook protein 2 GO:0043234//protein complex;GO:0000792//heterochromatin;GO:0043231//intracellular membrane-bounded organelle "GO:0004674//protein serine/threonine kinase activity;GO:0044212//transcription regulatory region DNA binding;GO:0016835//carbon-oxygen lyase activity;GO:0019904//protein domain specific binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0043565//sequence-specific DNA binding;GO:0031490//chromatin DNA binding" GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0008406//gonad development;GO:0048232//male gamete generation;GO:0001707//mesoderm formation;GO:0030252//growth hormone secretion;GO:0051100//negative regulation of binding;GO:0035264//multicellular organism growth;GO:0007259//JAK-STAT cascade;GO:0031507//heterochromatin assembly;GO:0045686//negative regulation of glial cell differentiation;GO:0035404//histone-serine phosphorylation;GO:0000904//cell morphogenesis involved in differentiation;GO:0021536//diencephalon development;GO:0035270//endocrine system development;GO:0031572//G2 DNA damage checkpoint;GO:0002791//regulation of peptide secretion;GO:0060612//adipose tissue development;GO:0001706//endoderm formation;GO:0007050//cell cycle arrest;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0009968//negative regulation of signal transduction;GO:0035690//cellular response to drug;GO:0045071//negative regulation of viral genome replication;GO:0006366//transcription from RNA polymerase II promoter;GO:0090398//cellular senescence;GO:0019827//stem cell population maintenance;GO:0048584;GO:0051707//response to other organism;GO:0032897//negative regulation of viral transcription;GO:0043388//positive regulation of DNA binding gi|940752924|ref|XP_014318211.1|/3.83685e-29/PREDICTED: uncharacterized protein LOC106698497 [Myotis lucifugus] 11928 3720 474.22 455.5833333 -0.057841539 Down 0.202668397 Atp1a1 "ATPase, Na+/K+ transporting, alpha 1 polypeptide" K01539|1|0.0|1971|mmu:11928|sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9] GO:0042383//sarcolemma;GO:0005887//integral component of plasma membrane;GO:0048770 GO:0019900//kinase binding;GO:0008556//potassium-transporting ATPase activity;GO:0031420;GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0016791//phosphatase activity GO:0032970//regulation of actin filament-based process;GO:0006814//sodium ion transport;GO:0009612//response to mechanical stimulus;GO:0006704//glucocorticoid biosynthetic process;GO:0042391//regulation of membrane potential;GO:0008016//regulation of heart contraction;GO:0009154//purine ribonucleotide catabolic process;GO:0006941//striated muscle contraction;GO:0042221//response to chemical;GO:0071805//potassium ion transmembrane transport;GO:0009152//purine ribonucleotide biosynthetic process;GO:0015992//proton transport gi|21450277|ref|NP_659149.1|/0/sodium/potassium-transporting ATPase subunit alpha-1 precursor [Mus musculus] 432530 12259 0.173333333 0.07 -1.308122295 Down 0.202611982 Adcy1 adenylate cyclase 1 K08041|1|0.0|1955|mmu:432530|adenylate cyclase 1 [EC:4.6.1.1] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0032550;GO:0005515//protein binding;GO:0004016//adenylate cyclase activity;GO:0043169//cation binding GO:0015980//energy derivation by oxidation of organic compounds;GO:0048511//rhythmic process;GO:0007267//cell-cell signaling;GO:0038127//ERBB signaling pathway;GO:0007613//memory;GO:0045762//positive regulation of adenylate cyclase activity;GO:0033762//response to glucagon;GO:0032147//activation of protein kinase activity;GO:0010863//positive regulation of phospholipase C activity;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0010038//response to metal ion;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0042044//fluid transport gi|61888832|ref|NP_033752.1|/0/adenylate cyclase type 1 [Mus musculus] 245240 2403 0.17 0.07 -1.280107919 Down 0.202611982 9930111J21Rik2 RIKEN cDNA 9930111J21 gene 2 K17072|1|1e-117|426|mmu:432555|interferon gamma inducible protein 47 - - - gi|27734112|ref|NP_775610.1|/0/interferon inducible GTPase [Mus musculus] 387314 8346 13.62 14.39666667 0.080008112 Up 0.202593178 Tmtc1 transmembrane and tetratricopeptide repeat containing 1 K09667|1|2e-28|132|crg:105329715|protein O-GlcNAc transferase [EC:2.4.1.255] - - - gi|164519037|ref|NP_945318.2|/0/transmembrane and TPR repeat-containing protein 1 [Mus musculus] 28075 2945 14.33666667 15.11333333 0.07611226 Up 0.202593178 Desi1 desumoylating isopeptidase 1 - GO:0043231//intracellular membrane-bounded organelle GO:0016787//hydrolase activity GO:0019538//protein metabolic process gi|635102546|ref|XP_007974111.1|/3.68401e-103/PREDICTED: desumoylating isopeptidase 1 [Chlorocebus sabaeus] 72278 2974.11 28.24666667 26.92666667 -0.069044983 Down 0.202433337 Ccpg1 cell cycle progression 1 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0050789;GO:0044763;GO:0006366//transcription from RNA polymerase II promoter;GO:0050789;GO:0044763;GO:0006366//transcription from RNA polymerase II promoter;GO:0050789;GO:0044763;GO:0006366//transcription from RNA polymerase II promoter;GO:0050789;GO:0044763;GO:0006366//transcription from RNA polymerase II promoter;GO:0050789;GO:0044763;GO:0006366//transcription from RNA polymerase II promoter gi|166998947|ref|NP_001107800.1|/0/cell cycle progression protein 1 isoform 1 [Mus musculus] 66066 849 26.45 25.13333333 -0.0736657 Down 0.202433337 Gng11 "guanine nucleotide binding protein (G protein), gamma 11" K04546|1|1e-34|149|ecb:100051499|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 GO:0031234//extrinsic component of cytoplasmic side of plasma membrane GO:0017111//nucleoside-triphosphatase activity;GO:0060089 GO:0009154//purine ribonucleotide catabolic process;GO:0033762//response to glucagon;GO:0007166//cell surface receptor signaling pathway;GO:0015980//energy derivation by oxidation of organic compounds gi|4758448|ref|NP_004117.1|/9.28832e-34/guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 precursor [Homo sapiens] 622208 1463 0.17 0.293333333 0.787006277 Up 0.20240513 Gm6297 predicted gene 6297 - - - - - 13855 4250.13 9.596666667 9.01 -0.091006277 Down 0.202254692 Epn2 epsin 2 K12471|1|0.0|994|mmu:13855|epsin GO:0030125//clathrin vesicle coat;GO:0030125//clathrin vesicle coat;GO:0030125//clathrin vesicle coat GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0043009//chordate embryonic development;GO:0007166//cell surface receptor signaling pathway;GO:0006897//endocytosis;GO:0043009//chordate embryonic development;GO:0007166//cell surface receptor signaling pathway;GO:0006897//endocytosis;GO:0043009//chordate embryonic development;GO:0007166//cell surface receptor signaling pathway;GO:0006897//endocytosis gi|50510771|dbj|BAD32371.1|/0/mKIAA1065 protein [Mus musculus] 216134 5110 10.04333333 9.45 -0.087851938 Down 0.202254692 Pdxk "pyridoxal (pyridoxine, vitamin B6) kinase" K00868|1|4e-177|625|mmu:216134|pyridoxine kinase [EC:2.7.1.35] GO:0044444//cytoplasmic part GO:0032550;GO:0070279;GO:0043168//anion binding;GO:0031420;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0016301//kinase activity GO:0009636//response to toxic substance;GO:0042823//pyridoxal phosphate biosynthetic process;GO:0048545//response to steroid hormone;GO:0010212//response to ionizing radiation;GO:0010243//response to organonitrogen compound;GO:0006915//apoptotic process;GO:0031667//response to nutrient levels gi|26006861|ref|NP_742146.1|/3.51629e-176/pyridoxal kinase [Mus musculus] 102334 2398.13 9.286666667 9.873333333 0.088376383 Up 0.202254692 Ankrd10 ankyrin repeat domain 10 K17593|1|2e-16|90.5|cin:100184405|ankyrin repeat domain-containing protein 42 - - - "gi|148690128|gb|EDL22075.1|/0/ankyrin repeat domain 10, isoform CRA_d, partial [Mus musculus]" 52040 4239 9.163333333 9.756666667 0.090515839 Up 0.202254692 Ppp1r10 "protein phosphatase 1, regulatory subunit 10" K17552|1|0.0|916|mmu:52040|protein phosphatase 1 regulatory subunit 10 GO:0043231//intracellular membrane-bounded organelle;GO:0008287//protein serine/threonine phosphatase complex;GO:0000785//chromatin GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0019903//protein phosphatase binding;GO:0019212//phosphatase inhibitor activity GO:0044092//negative regulation of molecular function;GO:0008152//metabolic process;GO:0006886//intracellular protein transport gi|444727362|gb|ELW67861.1|/0/Serine/threonine-protein phosphatase 1 regulatory subunit 10 [Tupaia chinensis] 16434 1264 9.453333333 10.04333333 0.08734314 Up 0.202254692 Itpa inosine triphosphatase (nucleoside triphosphate pyrophosphatase) K01519|1|1e-108|395|mmu:16434|inosine triphosphate pyrophosphatase [EC:3.6.1.19] GO:0044424 GO:0043169//cation binding;GO:0047429//nucleoside-triphosphate diphosphatase activity GO:0006996//organelle organization;GO:0009154//purine ribonucleotide catabolic process gi|31982664|ref|NP_080198.2|/8.33595e-108/inosine triphosphate pyrophosphatase [Mus musculus] 108689 1878 10.02666667 9.433333333 -0.088002514 Down 0.202254692 Obfc1 oligonucleotide/oligosaccharide-binding fold containing 1 - GO:0005856//cytoskeleton;GO:0000783//nuclear telomere cap complex GO:0003697//single-stranded DNA binding GO:0000723//telomere maintenance;GO:0006260//DNA replication gi|28827826|ref|NP_780569.1|/0/CST complex subunit STN1 [Mus musculus] 52653 1599 5.813333333 5.396666667 -0.107297054 Down 0.202245289 Nudcd2 NudC domain containing 2 - GO:0005819//spindle;GO:0000776//kinetochore;GO:0005819//spindle;GO:0000776//kinetochore - - gi|987951053|ref|XP_006766393.2|/9.03174e-70/PREDICTED: nudC domain-containing protein 2 isoform X2 [Myotis davidii] 18806 3679.91 5.616666667 5.196666667 -0.112127663 Down 0.202245289 Pld2 phospholipase D2 K01115|1|0.0|1902|mmu:18806|phospholipase D1/2 [EC:3.1.4.4] GO:0043231//intracellular membrane-bounded organelle;GO:0031252//cell leading edge;GO:0005903//brush border;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0031252//cell leading edge;GO:0005903//brush border;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0031252//cell leading edge;GO:0005903//brush border;GO:0044459 GO:0004620//phospholipase activity;GO:0019901//protein kinase binding;GO:0005543//phospholipid binding;GO:0004620//phospholipase activity;GO:0019901//protein kinase binding;GO:0005543//phospholipid binding;GO:0004620//phospholipase activity;GO:0019901//protein kinase binding;GO:0005543//phospholipid binding GO:0007155//cell adhesion;GO:0006898//receptor-mediated endocytosis;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0000302//response to reactive oxygen species;GO:0030030//cell projection organization;GO:0009967//positive regulation of signal transduction;GO:0009725//response to hormone;GO:0006644//phospholipid metabolic process;GO:0016477//cell migration;GO:0033008;GO:0007155//cell adhesion;GO:0006898//receptor-mediated endocytosis;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0000302//response to reactive oxygen species;GO:0030030//cell projection organization;GO:0009967//positive regulation of signal transduction;GO:0009725//response to hormone;GO:0006644//phospholipid metabolic process;GO:0016477//cell migration;GO:0033008;GO:0007155//cell adhesion;GO:0006898//receptor-mediated endocytosis;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0000302//response to reactive oxygen species;GO:0030030//cell projection organization;GO:0009967//positive regulation of signal transduction;GO:0009725//response to hormone;GO:0006644//phospholipid metabolic process;GO:0016477//cell migration;GO:0033008 gi|755537662|ref|XP_011247100.1|/0/PREDICTED: phospholipase D2 isoform X5 [Mus musculus] 100503915 1838 5.506666667 5.086666667 -0.114458725 Down 0.202245289 Smpd5 sphingomyelin phosphodiesterase 5 K12352|1|8e-74|280|mze:101480148|sphingomyelin phosphodiesterase 3 [EC:3.1.4.12] - - - - 19356 2735 5.836666667 5.416666667 -0.107739366 Down 0.202245289 Rad17 RAD17 checkpoint clamp loader component K06662|1|0.0|1203|mmu:19356|cell cycle checkpoint protein - - - - 71276 3437 0.696666667 0.87 0.320546864 Up 0.202235887 Ccdc57 coiled-coil domain containing 57 "K00665|1|0.0|766|bacu:103017465|fatty acid synthase, animal type [EC:2.3.1.85];K10421|2|2e-16|90.9|dan:Dana_GF14794|CAP-Gly domain-containing linker protein 1;K10352|5|2e-14|84.3|mze:101483420|myosin heavy chain" - - - gi|58037237|ref|NP_082021.1|/0/coiled-coil domain-containing protein 57 [Mus musculus] 69918 2156 0.87 0.696666667 -0.320546864 Down 0.202235887 2610020C07Rik RIKEN cDNA 2610020C07 gene K03267|1|4e-30|135|pps:100989064|peptide chain release factor subunit 3 - GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008079//translation termination factor activity GO:0008213;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0010467//gene expression gi|931596596|ref|XP_014197149.1|/3.168e-29/PREDICTED: LOW QUALITY PROTEIN: eukaryotic peptide chain release factor GTP-binding subunit ERF3A [Pan paniscus] 13706 912 0.716666667 0.556666667 -0.364488557 Down 0.202198277 Cela2a "chymotrypsin-like elastase family, member 2A" K01346|1|2e-143|510|mmu:13706|pancreatic elastase II [EC:3.4.21.71] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|6681297|ref|NP_031945.1|/1.81703e-142/chymotrypsin-like elastase family member 2A precursor [Mus musculus] 56438 1655 26.71 28.01333333 0.068733685 Up 0.202151266 Rbx1 ring-box 1 K03868|1|2e-64|249|tup:102468598|RING-box protein 1 GO:0031981//nuclear lumen;GO:0000152//nuclear ubiquitin ligase complex;GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0000153//cytoplasmic ubiquitin ligase complex GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0031369//translation initiation factor binding GO:0007166//cell surface receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006259//DNA metabolic process;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0016567//protein ubiquitination;GO:0001666//response to hypoxia "gi|32425477|gb|AAH17370.2|/4.84553e-64/RBX1 protein, partial [Homo sapiens]" 73040 2585 0.48 0.34 -0.497499659 Down 0.202123058 2900052N01Rik RIKEN cDNA 2900052N01 gene - - - - - 234673 2310.15 1.17 1.376666667 0.234670751 Up 0.202104254 Ces2e carboxylesterase 2E K03927|1|0.0|1133|mmu:234673|carboxylesterase 2 [EC:3.1.1.1 3.1.1.84 3.1.1.56] GO:0043227//membrane-bounded organelle;GO:0043227//membrane-bounded organelle GO:0052689//carboxylic ester hydrolase activity;GO:0052689//carboxylic ester hydrolase activity - "gi|148679291|gb|EDL11238.1|/0/carboxylesterase 5, isoform CRA_a, partial [Mus musculus]" 109082 1832 1.446666667 1.236666667 -0.226275856 Down 0.202104254 Fbxw17 F-box and WD-40 domain protein 17 K10267|1|0.0|927|mmu:109082|F-box and WD-40 domain protein 12/13/14/15/16/17/19 - - - "gi|148709146|gb|EDL41092.1|/0/F-box and WD-40 domain protein 17, isoform CRA_b, partial [Mus musculus]" 216152 3054.25 1.223333333 1.43 0.225197585 Up 0.202104254 Plppr3 phospholipid phosphatase related 3 K19582|1|0.0|1266|mmu:216152|lipid phosphate phosphatase-related protein type 3/4 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0016791//phosphatase activity;GO:0005488//binding;GO:0016791//phosphatase activity;GO:0005488//binding;GO:0016791//phosphatase activity - gi|283945516|ref|NP_859009.2|/0/phospholipid phosphatase-related protein type 3 isoform 1 [Mus musculus] 20533 4584 0.18 0.076666667 -1.231325546 Down 0.202057242 Slc4a1 "solute carrier family 4 (anion exchanger), member 1" "K06573|1|0.0|1541|mmu:20533|solute carrier family 4 (anion exchanger), member 1" GO:0005856//cytoskeleton;GO:0044459;GO:0016021//integral component of membrane;GO:0031674//I band GO:0042802//identical protein binding;GO:0008092//cytoskeletal protein binding;GO:0015301//anion:anion antiporter activity;GO:0015103//inorganic anion transmembrane transporter activity GO:0015698//inorganic anion transport gi|6755560|ref|NP_035533.1|/0/band 3 anion transport protein [Mus musculus] 666731 1990 0.18 0.076666667 -1.231325546 Down 0.202057242 Trim43c tripartite motif-containing 43C K12019|1|0.0|927|mmu:666731|tripartite motif-containing protein 43/48/49/64/77 GO:0044464 GO:0046914//transition metal ion binding - gi|295390679|ref|NP_001171329.1|/0/tripartite motif-containing protein 43C [Mus musculus] 100503549 795 0.07 0.166666667 1.251538767 Up 0.202057242 Gm10354 predicted gene 10354 - - - - gi|528078322|ref|NP_001268443.1|/4.88715e-119/spermatogenesis associated glutamate (E)-rich protein-like [Mus musculus] 104318 3708.93 27.23666667 25.94666667 -0.070000942 Down 0.202029035 Csnk1d "casein kinase 1, delta" "K08959|1|0.0|804|cge:100751124|casein kinase 1, delta [EC:2.7.11.1]" GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0044444//cytoplasmic part GO:0032550;GO:0005515//protein binding;GO:0033218//amide binding;GO:0004672//protein kinase activity;GO:0032550;GO:0005515//protein binding;GO:0033218//amide binding;GO:0004672//protein kinase activity GO:0044772//mitotic cell cycle phase transition;GO:0006461//protein complex assembly;GO:0006259//DNA metabolic process;GO:0001932//regulation of protein phosphorylation;GO:0008104//protein localization;GO:0031331;GO:0030177//positive regulation of Wnt signaling pathway;GO:0007623//circadian rhythm;GO:0044772//mitotic cell cycle phase transition;GO:0006461//protein complex assembly;GO:0006259//DNA metabolic process;GO:0001932//regulation of protein phosphorylation;GO:0031331;GO:0030177//positive regulation of Wnt signaling pathway;GO:0007623//circadian rhythm gi|585660036|ref|XP_006886188.1|/0/PREDICTED: casein kinase I isoform delta isoform X3 [Elephantulus edwardii] 78920 2767 346.8766667 333.7033333 -0.055856701 Down 0.201963218 Dlst dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) K00658|1|0.0|707|mmu:78920|2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0016020//membrane GO:0016751//S-succinyltransferase activity;GO:0005515//protein binding GO:0043648//dicarboxylic acid metabolic process;GO:0019474;GO:0009060//aerobic respiration;GO:0019674//NAD metabolic process "gi|21313536|ref|NP_084501.1|/0/dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial [Mus musculus]" 109331 4159 7.276666667 6.81 -0.095622926 Down 0.201916206 Rnf20 ring finger protein 20 K10696|1|0.0|1575|mmu:109331|E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27] GO:0031981//nuclear lumen;GO:0000151//ubiquitin ligase complex;GO:0031981//nuclear lumen;GO:0000151//ubiquitin ligase complex GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003712//transcription cofactor activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003712//transcription cofactor activity;GO:0019787//ubiquitin-like protein transferase activity "GO:0006351//transcription, DNA-templated;GO:0006513//protein monoubiquitination;GO:0016571//histone methylation;GO:0016574//histone ubiquitination;GO:0019941//modification-dependent protein catabolic process;GO:0016477//cell migration;GO:0006351//transcription, DNA-templated;GO:0006513//protein monoubiquitination;GO:0016571//histone methylation;GO:0016574//histone ubiquitination;GO:0019941//modification-dependent protein catabolic process;GO:0016477//cell migration" gi|60360142|dbj|BAD90290.1|/0/mKIAA4116 protein [Mus musculus] 404634 1910 3.566666667 3.906666667 0.131361773 Up 0.201878596 H2afy2 "H2A histone family, member Y2" K11251|1|2e-173|612|rno:361844|histone H2A - - - - 16005 2111 3.866666667 3.53 -0.131422216 Down 0.201878596 Igfals "insulin-like growth factor binding protein, acid labile subunit" K17256|1|0.0|1036|mmu:16005|insulin-like growth factor-binding protein complex acid labile subunit GO:0016942//insulin-like growth factor binding protein complex;GO:0031981//nuclear lumen GO:0019838//growth factor binding GO:0022610;GO:0007154//cell communication gi|60359992|dbj|BAD90215.1|/0/mKIAA4111 protein [Mus musculus] 319944 5033 3.916666667 3.58 -0.129666763 Down 0.201878596 Taf2 TATA-box binding protein associated factor 2 K03128|1|0.0|2330|mmu:319944|transcription initiation factor TFIID subunit 2 GO:0005667//transcription factor complex "GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0000975//regulatory region DNA binding" GO:0006366//transcription from RNA polymerase II promoter gi|124486849|ref|NP_001074757.1|/0/transcription initiation factor TFIID subunit 2 [Mus musculus] 100163 3042.16 4.04 3.7 -0.126830022 Down 0.201878596 Pafah2 platelet-activating factor acetylhydrolase 2 K01062|1|0.0|797|mmu:100163|platelet-activating factor acetylhydrolase [EC:3.1.1.47] GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0006629//lipid metabolic process;GO:0006915//apoptotic process;GO:0006629//lipid metabolic process;GO:0006915//apoptotic process;GO:0006629//lipid metabolic process;GO:0006915//apoptotic process;GO:0006629//lipid metabolic process;GO:0006915//apoptotic process;GO:0006629//lipid metabolic process;GO:0006915//apoptotic process "gi|552953737|ref|NP_001272801.1|/0/platelet-activating factor acetylhydrolase 2, cytoplasmic isoform a [Mus musculus]" 68874 1555 3.626666667 3.966666667 0.129283017 Up 0.201878596 Klhdc9 kelch domain containing 9 K10455|1|9e-06|54.3|bfo:BRAFLDRAFT_74807|kelch-like protein 18 - - - gi|85986583|ref|NP_001028211.1|/0/kelch domain-containing protein 9 [Mus musculus] 79264 6119.3 3.956666667 3.62 -0.128295832 Down 0.201878596 Krit1 "KRIT1, ankyrin repeat containing" K17705|1|0.0|1468|mmu:79264|Krev interaction trapped protein 1 GO:0030054//cell junction;GO:0032991//macromolecular complex;GO:0043232;GO:0016020//membrane;GO:0030054//cell junction;GO:0032991//macromolecular complex;GO:0043232;GO:0016020//membrane;GO:0030054//cell junction;GO:0032991//macromolecular complex;GO:0043232;GO:0016020//membrane GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0005488//binding;GO:0030695//GTPase regulator activity GO:0001525//angiogenesis;GO:0043393//regulation of protein binding;GO:0019222//regulation of metabolic process;GO:0019725//cellular homeostasis;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0001935//endothelial cell proliferation;GO:0010594//regulation of endothelial cell migration;GO:0043066//negative regulation of apoptotic process;GO:0001525//angiogenesis;GO:0043393//regulation of protein binding;GO:0019222//regulation of metabolic process;GO:0019725//cellular homeostasis;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0001935//endothelial cell proliferation;GO:0010594//regulation of endothelial cell migration;GO:0043066//negative regulation of apoptotic process;GO:0001525//angiogenesis;GO:0043393//regulation of protein binding;GO:0019222//regulation of metabolic process;GO:0019725//cellular homeostasis;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0001935//endothelial cell proliferation;GO:0010594//regulation of endothelial cell migration;GO:0043066//negative regulation of apoptotic process "gi|148682673|gb|EDL14620.1|/0/KRIT1, ankyrin repeat containing, isoform CRA_c, partial [Mus musculus]" 64899 3462.53 3.6 3.943333333 0.131418761 Up 0.201878596 Lpin3 lipin 3 K15728|1|0.0|1538|mmu:64899|phosphatidate phosphatase LPIN [EC:3.1.3.4] - GO:0016791//phosphatase activity;GO:0016791//phosphatase activity GO:0044238//primary metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0044238//primary metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006796//phosphate-containing compound metabolic process gi|60359868|dbj|BAD90153.1|/0/mKIAA4023 protein [Mus musculus] 21411 7319.09 2.703333333 2.42 -0.159732366 Down 0.201840987 Tcf20 transcription factor 20 K19749|1|2e-67|261|gga:427664|retinoic acid-induced protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter gi|166706889|ref|NP_038864.3|/0/transcription factor 20 isoform b [Mus musculus] 266632 2825 2.336666667 2.613333333 0.16143921 Up 0.201840987 Irak4 interleukin-1 receptor-associated kinase 4 K04733|1|0.0|874|mmu:266632|interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1] GO:0031090//organelle membrane;GO:0044444//cytoplasmic part GO:0032550;GO:0004672//protein kinase activity;GO:0005126//cytokine receptor binding;GO:0046872//metal ion binding GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0044707;GO:0006796//phosphate-containing compound metabolic process;GO:0002224//toll-like receptor signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0006464//cellular protein modification process;GO:0051403//stress-activated MAPK cascade gi|23943898|ref|NP_084202.2|/0/interleukin-1 receptor-associated kinase 4 [Mus musculus] 218442 5393 2.74 2.46 -0.155517578 Down 0.201840987 Serinc5 serine incorporator 5 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0015179//L-amino acid transmembrane transporter activity GO:0008366//axon ensheathment;GO:0006644//phospholipid metabolic process;GO:0006575//cellular modified amino acid metabolic process;GO:0006643//membrane lipid metabolic process;GO:0043085//positive regulation of catalytic activity;GO:0015807//L-amino acid transport gi|27369834|ref|NP_766176.1|/0/serine incorporator 5 [Mus musculus] 67298 5718.71 2.42 2.703333333 0.159732366 Up 0.201840987 Gprasp1 G protein-coupled receptor associated sorting protein 1 K04574|1|2e-08|65.1|shr:100913759|neurofilament heavy polypeptide;K15176|2|1e-07|62.8|tca:657922|RNA polymerase-associated protein CTR9 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - gi|26006165|dbj|BAC41425.1|/0/mKIAA0443 protein [Mus musculus] 268396 7432 1.71 1.946666667 0.187009543 Up 0.201737561 Sh3pxd2b SH3 and PX domains 2B K08011|1|4e-54|217|bacu:103021081|neutrophil cytosolic factor 1 GO:0015629//actin cytoskeleton GO:1901981//phosphatidylinositol phosphate binding;GO:0043168//anion binding;GO:0019904//protein domain specific binding GO:0007423//sensory organ development;GO:0022411;GO:0072593//reactive oxygen species metabolic process;GO:0001501//skeletal system development;GO:0006461//protein complex assembly;GO:0045444//fat cell differentiation gi|63055065|ref|NP_796338.2|/0/SH3 and PX domain-containing protein 2B [Mus musculus] 74670 2736 1.94 1.7 -0.190521906 Down 0.201737561 Zfp943 zinc finger prtoein 943 K09228|1|0.0|734|mmu:240038|KRAB domain-containing zinc finger protein - - - "gi|148673810|gb|EDL05757.1|/0/RIKEN cDNA 4930432O21, isoform CRA_b, partial [Mus musculus]" 239528 8031 1.926666667 1.686666667 -0.191932108 Down 0.201737561 Ago2 argonaute RISC catalytic subunit 2 K11593|1|0.0|1762|mmu:239528|eukaryotic translation initiation factor 2C GO:0043231//intracellular membrane-bounded organelle;GO:0034518//RNA cap binding complex;GO:0035770//ribonucleoprotein granule;GO:0031332//RNAi effector complex;GO:0044444//cytoplasmic part "GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0043169//cation binding;GO:0008135//translation factor activity, RNA binding;GO:0000339//RNA cap binding" "GO:0006351//transcription, DNA-templated;GO:0006413//translational initiation;GO:0007166//cell surface receptor signaling pathway;GO:0007275//multicellular organism development;GO:0006379//mRNA cleavage;GO:0048869//cellular developmental process;GO:0035196//production of miRNAs involved in gene silencing by miRNA" gi|219842353|ref|NP_694818.3|/0/protein argonaute-2 [Mus musculus] 74096 2652 1.65 1.886666667 0.193373528 Up 0.201737561 Hvcn1 hydrogen voltage-gated channel 1 K19382|1|7e-13|79.0|mmu:654470|tectonic-1/3 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0015252//hydrogen ion channel activity;GO:0015252//hydrogen ion channel activity GO:0034220//ion transmembrane transport;GO:0009628//response to abiotic stimulus;GO:0006818//hydrogen transport;GO:0010038//response to metal ion;GO:0034220//ion transmembrane transport;GO:0009628//response to abiotic stimulus;GO:0006818//hydrogen transport;GO:0010038//response to metal ion gi|21311863|ref|NP_083028.1|/8.05303e-94/voltage-gated hydrogen channel 1 [Mus musculus] 100040852 5292 1.013333333 0.83 -0.287925581 Down 0.201690549 Gm3002 alpha-takusan pseudogene "K03844|1|2e-16|91.7|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131];K04332|2|3e-06|58.2|mmu:19214|prostaglandin D2 receptor" - - - gi|755546841|ref|XP_011243026.1|/6.77632e-94/PREDICTED: predicted gene 3264 isoform X1 [Mus musculus] 224836 5598 0.986666667 0.806666667 -0.290590128 Down 0.201690549 Usp49 ubiquitin specific peptidase 49 K11834|1|0.0|1292|mmu:224836|ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019941//modification-dependent protein catabolic process gi|38259220|ref|NP_940813.1|/0/ubiquitin carboxyl-terminal hydrolase 49 [Mus musculus] 330863 8832 0.383333333 0.253333333 -0.597562538 Down 0.201690549 Trim67 tripartite motif-containing 67 K10649|1|0.0|1382|mmu:330863|tripartite motif-containing protein 9/67 GO:0043232 GO:0046914//transition metal ion binding GO:0007265//Ras protein signal transduction;GO:0031398//positive regulation of protein ubiquitination;GO:0010975//regulation of neuron projection development gi|254939710|ref|NP_941034.2|/0/tripartite motif-containing protein 67 [Mus musculus] 69540 1354 0.256666667 0.383333333 0.57870351 Up 0.201671744 Klk10 kallikrein related-peptidase 10 K09619|1|2e-157|557|mmu:69540|kallikrein 10 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process "gi|148690731|gb|EDL22678.1|/3.58048e-168/kallikrein 10, isoform CRA_a, partial [Mus musculus]" 53600 1162 270.2733333 281.59 0.059176926 Up 0.20161533 Timm23 translocase of inner mitochondrial membrane 23 K17794|1|2e-85|318|mmu:53600|mitochondrial import inner membrane translocase subunit TIM23 GO:0031304//intrinsic component of mitochondrial inner membrane GO:0008320//protein transmembrane transporter activity;GO:0005515//protein binding GO:0006605//protein targeting;GO:0019538//protein metabolic process gi|254675168|ref|NP_058593.2|/1.49242e-84/mitochondrial import inner membrane translocase subunit Tim23 [Mus musculus] 28295 1363 256.0033333 244.7833333 -0.064657263 Down 0.201605927 D10Jhu81e "DNA segment, Chr 10, Johns Hopkins University 81 expressed" - - - - "gi|20070420|ref|NP_613067.1|/1.93502e-137/ES1 protein homolog, mitochondrial precursor [Mus musculus]" 208715 3533.47 9.63 9.05 -0.089618006 Down 0.201558915 Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 K01641|1|0.0|1052|mmu:208715|hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0016020//membrane "GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer;GO:0042802//identical protein binding;GO:0036094//small molecule binding;GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer;GO:0042802//identical protein binding;GO:0036094//small molecule binding" GO:0009642//response to light intensity;GO:0010035//response to inorganic substance;GO:0007417//central nervous system development;GO:0010243//response to organonitrogen compound;GO:0036315//cellular response to sterol;GO:0032354//response to follicle-stimulating hormone;GO:0006720//isoprenoid metabolic process;GO:0006694//steroid biosynthetic process;GO:0008406//gonad development;GO:0008203//cholesterol metabolic process;GO:0009642//response to light intensity;GO:0010035//response to inorganic substance;GO:0007417//central nervous system development;GO:0010243//response to organonitrogen compound;GO:0036315//cellular response to sterol;GO:0032354//response to follicle-stimulating hormone;GO:0006720//isoprenoid metabolic process;GO:0006694//steroid biosynthetic process;GO:0008406//gonad development;GO:0008203//cholesterol metabolic process "gi|148686390|gb|EDL18337.1|/0/3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1, isoform CRA_b, partial [Mus musculus]" 243382 5560 8.593333333 9.173333333 0.094228206 Up 0.201558915 Ppm1k protein phosphatase 1K (PP2C domain containing) K17505|1|0.0|725|mmu:243382|protein phosphatase 1K [EC:3.1.3.16] GO:0044429 GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity GO:0006464//cellular protein modification process "gi|30425290|ref|NP_780732.1|/0/protein phosphatase 1K, mitochondrial precursor [Mus musculus]" 78653 530 274.0933333 263.11 -0.059001157 Down 0.201530708 Bola3 bolA-like 3 (E. coli) - - - - gi|30424938|ref|NP_780486.1|/9.76269e-38/bolA-like protein 3 [Mus musculus] 17289 3564 4.516666667 4.143333333 -0.124466555 Down 0.201502501 Mertk c-mer proto-oncogene tyrosine kinase K05117|1|0.0|1907|mmu:17289|c-mer proto-oncogene tyrosine kinase [EC:2.7.10.1] GO:0031513//nonmotile primary cilium;GO:0016021//integral component of membrane;GO:0044421 GO:0032550;GO:0004713//protein tyrosine kinase activity GO:0006909//phagocytosis;GO:0007599//hemostasis;GO:0043010//camera-type eye development;GO:0006796//phosphate-containing compound metabolic process;GO:0002695//negative regulation of leukocyte activation;GO:0000904//cell morphogenesis involved in differentiation;GO:0030540//female genitalia development;GO:0048232//male gamete generation;GO:0006464//cellular protein modification process;GO:0030098//lymphocyte differentiation;GO:0046903//secretion gi|7106355|ref|NP_032613.1|/0/tyrosine-protein kinase Mer precursor [Mus musculus] 66503 1802 4.106666667 4.473333333 0.123382416 Up 0.201502501 1810034E14Rik RIKEN cDNA 1810034E14 gene - - - - - 20317 1497 25.75333333 24.50666667 -0.071584911 Down 0.20141788 Serpinf1 "serine (or cysteine) peptidase inhibitor, clade F, member 1" K19614|1|0.0|747|mmu:20317|pigment epithelium-derived factor GO:0044421 GO:0004866//endopeptidase inhibitor activity GO:0001525//angiogenesis;GO:0007613//memory;GO:0006954//inflammatory response;GO:0050680//negative regulation of epithelial cell proliferation;GO:0010720//positive regulation of cell development;GO:0031960//response to corticosteroid gi|117606335|ref|NP_035470.3|/0/pigment epithelium-derived factor precursor [Mus musculus] 69912 1290 2.076666667 1.83 -0.182426014 Down 0.201352063 Nup43 nucleoporin 43 K14305|1|0.0|793|mmu:69912|nuclear pore complex protein Nup43 GO:0005643//nuclear pore;GO:0000776//kinetochore;GO:0044444//cytoplasmic part GO:0005488//binding GO:0044238//primary metabolic process;GO:0044710;GO:0044764;GO:0050658//RNA transport;GO:0045184//establishment of protein localization;GO:0015758//glucose transport;GO:0007166//cell surface receptor signaling pathway;GO:0007067//mitotic nuclear division "gi|148671597|gb|EDL03544.1|/0/nucleoporin 43, isoform CRA_a, partial [Mus musculus]" 16440 9012 2.213333333 1.96 -0.175367087 Down 0.201352063 Itpr3 "inositol 1,4,5-triphosphate receptor 3" "K04960|1|0.0|5116|mmu:16440|inositol 1,4,5-triphosphate receptor type 3" GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0031965//nuclear membrane;GO:0044297//cell body;GO:0016021//integral component of membrane GO:0005217//intracellular ligand-gated ion channel activity;GO:0046873//metal ion transmembrane transporter activity;GO:0005543//phospholipid binding;GO:0005261//cation channel activity;GO:0046872//metal ion binding;GO:0043168//anion binding GO:0007166//cell surface receptor signaling pathway;GO:0007611//learning or memory;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0006816//calcium ion transport;GO:0050909//sensory perception of taste;GO:0048167//regulation of synaptic plasticity;GO:0051259//protein oligomerization;GO:0010038//response to metal ion;GO:0019932//second-messenger-mediated signaling "gi|568999131|ref|XP_006523775.1|/0/PREDICTED: inositol 1,4,5-trisphosphate receptor type 3 isoform X1 [Mus musculus]" 15118 5912 0.183333333 0.08 -1.196397213 Down 0.201352063 Has3 hyaluronan synthase 3 K00752|1|0.0|1085|mmu:15118|hyaluronan synthase [EC:2.4.1.212] GO:0031224//intrinsic component of membrane;GO:0044421 GO:0008194//UDP-glycosyltransferase activity "GO:0006024//glycosaminoglycan biosynthetic process;GO:0051130//positive regulation of cellular component organization;GO:0006351//transcription, DNA-templated" gi|170932538|ref|NP_032243.2|/0/hyaluronan synthase 3 [Mus musculus] 75304 3313 0.073333333 0.17 1.212993723 Up 0.201352063 4930563E22Rik RIKEN cDNA 4930563E22 gene K10314|1|6e-09|66.2|ssc:100521293|F-box protein 39 - - - gi|74205727|dbj|BAE21139.1|/8.9524e-37/unnamed protein product [Mus musculus] 14228 2167 222.69 232.83 0.064240186 Up 0.201333258 Fkbp4 FK506 binding protein 4 K09571|1|0.0|826|mmu:14228|FK506-binding protein 4/5 [EC:5.2.1.8] - - - gi|6753882|ref|NP_034349.1|/0/peptidyl-prolyl cis-trans isomerase FKBP4 [Mus musculus] 19015 3240 26.52333333 27.76666667 0.066091897 Up 0.201248637 Ppard peroxisome proliferator activator receptor delta K04504|1|0.0|861|mmu:19015|peroxisome proliferator-activated receptor delta GO:0043231//intracellular membrane-bounded organelle "GO:0036041//long-chain fatty acid binding;GO:0030234//enzyme regulator activity;GO:0042974//retinoic acid receptor binding;GO:0003712//transcription cofactor activity;GO:0003677//DNA binding;GO:0004955//prostaglandin receptor activity;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding" GO:0006954//inflammatory response;GO:0007272//ensheathment of neurons;GO:0006915//apoptotic process;GO:0006869//lipid transport;GO:0001893//maternal placenta development;GO:0042311//vasodilation;GO:0016049//cell growth;GO:0009967//positive regulation of signal transduction;GO:0022405//hair cycle process;GO:0009062//fatty acid catabolic process;GO:0008544//epidermis development;GO:0045444//fat cell differentiation;GO:0001523//retinoid metabolic process;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007155//cell adhesion;GO:0009755//hormone-mediated signaling pathway;GO:0033273//response to vitamin;GO:0009746;GO:0050796//regulation of insulin secretion;GO:0014909//smooth muscle cell migration;GO:0010558;GO:0009100//glycoprotein metabolic process;GO:0006644//phospholipid metabolic process gi|33859590|ref|NP_035275.1|/0/peroxisome proliferator-activated receptor delta [Mus musculus] 16994 1122 0.176666667 0.3 0.763932642 Up 0.201229832 Ltb lymphotoxin B "K03157|1|6e-136|486|mmu:16994|lymphotoxin beta (TNF superfamily, member 3)" - - - - 21753 2442 2.943333333 2.653333333 -0.149645007 Down 0.201173418 Tes testis derived transcript K04511|1|2e-85|320|crg:105339963|prickle GO:0005924//cell-substrate adherens junction;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0044424 GO:0046914//transition metal ion binding GO:0008283//cell proliferation gi|46395466|ref|NP_997059.1|/0/testin [Mus musculus] 232078 2018 2.74 3.033333333 0.146728151 Up 0.201173418 Thnsl2 threonine synthase-like 2 (bacterial) - - GO:0016838;GO:0016597//amino acid binding;GO:0016838;GO:0016597//amino acid binding GO:0046361;GO:0006566//threonine metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0009063//cellular amino acid catabolic process;GO:0046361;GO:0006566//threonine metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0009063//cellular amino acid catabolic process gi|76677922|ref|NP_848500.3|/0/threonine synthase-like 2 [Mus musculus] 109929 1681 2.856666667 2.566666667 -0.154436759 Down 0.201173418 Zbtb25 zinc finger and BTB domain containing 25 K10504|1|0.0|862|mmu:109929|zinc finger and BTB domain-containing protein 25 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010467//gene expression;GO:0010467//gene expression gi|568978642|ref|XP_006515454.1|/0/PREDICTED: zinc finger and BTB domain-containing protein 25 isoform X2 [Mus musculus] 244891 5259 3.05 2.756666667 -0.145884414 Down 0.201173418 Scaper S phase cyclin A-associated protein in the ER - - - - gi|124486797|ref|NP_001074810.1|/0/S phase cyclin A-associated protein in the endoplasmic reticulum [Mus musculus] 18655 1840 216.0033333 225.21 0.060217313 Up 0.20114521 Pgk1 phosphoglycerate kinase 1 K00927|1|0.0|828|mmu:18655|phosphoglycerate kinase [EC:2.7.2.3] - - - - 380664 4754 3.21 2.903333333 -0.144863079 Down 0.201088796 Lemd3 LEM domain containing 3 K19410|1|0.0|1384|mmu:380664|inner nuclear membrane protein Man1 - - - gi|145864461|ref|NP_001074662.2|/0/inner nuclear membrane protein Man1 [Mus musculus] 116914 3457 3.353333333 3.046666667 -0.138364235 Down 0.201088796 Slc19a2 "solute carrier family 19 (thiamine transporter), member 2" "K14610|1|0.0|884|rno:289175|solute carrier family 19 (thiamine transporter), member 2/3" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0019842//vitamin binding;GO:0015234//thiamine transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0019842//vitamin binding;GO:0015234//thiamine transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0006790//sulfur compound metabolic process;GO:0006766//vitamin metabolic process;GO:0006835//dicarboxylic acid transport;GO:0015888//thiamine transport;GO:0006790//sulfur compound metabolic process;GO:0006766//vitamin metabolic process;GO:0006835//dicarboxylic acid transport;GO:0015888//thiamine transport "gi|148707313|gb|EDL39260.1|/0/solute carrier family 19 (thiamine transporter), member 2, isoform CRA_b, partial [Mus musculus]" 73699 3629.54 3.13 3.44 0.136245908 Up 0.201088796 Ppp2r1b "protein phosphatase 2, regulatory subunit A, beta" K03456|1|0.0|1122|mmu:73699|serine/threonine-protein phosphatase 2A regulatory subunit A - - GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand gi|755529203|ref|XP_011240916.1|/0/PREDICTED: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1 [Mus musculus] 69401 763 0.076666667 0.173333333 1.176877762 Up 0.201088796 Plac8l1 PLAC8-like 1 K07188|1|1e-17|92.4|amj:102571969|hormone-sensitive lipase [EC:3.1.1.79] - - - "gi|148678095|gb|EDL10042.1|/2.80686e-105/mCG144591, partial [Mus musculus]" 54394 2326.2 2.946666667 3.253333333 0.142834778 Up 0.201088796 Crlf3 cytokine receptor-like factor 3 - - - - - 241070 1798 0.303333333 0.18 -0.752907138 Down 0.201051187 Gpr1 G protein-coupled receptor 1 K04310|1|0.0|681|mmu:241070|G protein-coupled receptor 1 GO:0016021//integral component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|22122833|ref|NP_666362.1|/0/G-protein coupled receptor 1 [Mus musculus] 434396 2342 0.17 0.286666667 0.753839413 Up 0.201051187 Gm5615 predicted gene 5615 - - - - gi|85702097|ref|NP_001028955.1|/2.18565e-55/prostate and testis expressed H precursor [Mus musculus] 216725 7265 5.79 5.38 -0.105957175 Down 0.201032382 Adamts2 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2" K08618|1|0.0|2350|mmu:216725|a disintegrin and metalloproteinase with thrombospondin motifs 2 [EC:3.4.24.14] GO:0031012//extracellular matrix GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0030323//respiratory tube development;GO:0008544//epidermis development;GO:0051604//protein maturation;GO:0032963//collagen metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0048232//male gamete generation;GO:0030198//extracellular matrix organization gi|33563307|ref|NP_783574.1|/0/A disintegrin and metalloproteinase with thrombospondin motifs 2 preproprotein [Mus musculus] 106068 4300.65 5.206666667 5.613333333 0.108497685 Up 0.201032382 Slc45a4 "solute carrier family 45, member 4" "K15378|1|0.0|1176|mmu:106068|solute carrier family 45, member 1/2/4" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0051234//establishment of localization gi|269914132|ref|NP_001028391.2|/0/solute carrier family 45 member 4 isoform 1 [Mus musculus] 16329 1786 5.24 5.646666667 0.107832657 Up 0.201032382 Inpp1 inositol polyphosphate-1-phosphatase K01107|1|0.0|785|mmu:16329|inositol polyphosphate 1-phosphatase [EC:3.1.3.57] - GO:0016312//inositol bisphosphate phosphatase activity;GO:0043169//cation binding GO:0046488//phosphatidylinositol metabolic process;GO:0007154//cell communication gi|170650609|ref|NP_032410.2|/0/inositol polyphosphate 1-phosphatase [Mus musculus] 237336 2880 5.333333333 5.74 0.106013238 Up 0.201032382 Tbpl1 TATA box binding protein-like 1 K03120|1|1e-101|374|tup:102498567|transcription initiation factor TFIID TATA-box-binding protein GO:0005667//transcription factor complex GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding "GO:0048232//male gamete generation;GO:0009212//pyrimidine deoxyribonucleoside triphosphate biosynthetic process;GO:0006997//nucleus organization;GO:0006351//transcription, DNA-templated;GO:0003006//developmental process involved in reproduction" gi|958729596|ref|XP_014706054.1|/3.0397e-102/PREDICTED: TATA box-binding protein-like protein 1 isoform X2 [Equus asinus] 56196 1977 5.456666667 5.05 -0.111736528 Down 0.201032382 Tdp2 tyrosyl-DNA phosphodiesterase 2 K19619|1|0.0|707|mmu:56196|tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-] GO:0016604//nuclear body GO:0070259;GO:0046914//transition metal ion binding;GO:0043566//structure-specific DNA binding GO:0006281//DNA repair gi|9507213|ref|NP_062424.1|/0/tyrosyl-DNA phosphodiesterase 2 [Mus musculus] 67673 508 219.47 228.1933333 0.056232897 Up 0.201013577 Tceb2 "transcription elongation factor B (SIII), polypeptide 2" "K03873|1|2e-62|239|hgl:101715777|transcription elongation factor B, polypeptide 2" GO:0031981//nuclear lumen;GO:0000153//cytoplasmic ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex "GO:0044389//ubiquitin-like protein ligase binding;GO:0008135//translation factor activity, RNA binding;GO:0019787//ubiquitin-like protein transferase activity" GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006412//translation;GO:0044764;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0001666//response to hypoxia;GO:0065003;GO:0032446//protein modification by small protein conjugation gi|861487244|ref|XP_004864733.2|/1.0964e-61/PREDICTED: transcription elongation factor B polypeptide 2 [Heterocephalus glaber] 218038 3235 0.766666667 0.603333333 -0.345644164 Down 0.200919553 Amph amphiphysin K12562|1|0.0|1090|mmu:218038|amphiphysin GO:0008021//synaptic vesicle;GO:0043232;GO:0033267;GO:0008021//synaptic vesicle;GO:0043232;GO:0033267 GO:0046983//protein dimerization activity;GO:0046983//protein dimerization activity GO:0043087//regulation of GTPase activity;GO:0007611//learning or memory;GO:0006897//endocytosis;GO:0043087//regulation of GTPase activity;GO:0007611//learning or memory;GO:0006897//endocytosis gi|575501703|ref|NP_001276475.1|/0/amphiphysin isoform 2 [Mus musculus] 235180 1285 0.576666667 0.736666667 0.353274332 Up 0.200919553 Fez1 fasciculation and elongation protein zeta 1 (zygin I) K16502|1|1e-70|269|acs:100557797|cadherin-related family member 2 GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0016020//membrane GO:0019901//protein kinase binding;GO:0015631//tubulin binding GO:0022610;GO:0070848//response to growth factor;GO:0006935//chemotaxis;GO:0051646//mitochondrion localization;GO:0051234//establishment of localization;GO:0010975//regulation of neuron projection development gi|148747561|ref|NP_898994.2|/0/fasciculation and elongation protein zeta-1 [Mus musculus] 75572 671 27.57666667 26.35666667 -0.065280158 Down 0.200910151 Acyp2 "acylphosphatase 2, muscle type" K01512|1|3e-54|213|mmu:75572|acylphosphatase [EC:3.6.1.7] GO:0043231//intracellular membrane-bounded organelle - - gi|27229219|ref|NP_083620.1|/2.48324e-53/acylphosphatase-2 [Mus musculus] 208990 549 0.29 0.173333333 -0.742503778 Down 0.200910151 Npb neuropeptide B K05267|1|3e-54|212|mmu:208990|preproneuropeptide B GO:0044421 - GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway gi|23463265|ref|NP_695020.1|/2.40455e-53/neuropeptide B precursor [Mus musculus] 328110 4096 6.133333333 6.593333333 0.10433666 Up 0.200891346 Prpf39 pre-mRNA processing factor 39 K13217|1|0.0|1284|mmu:328110|pre-mRNA-processing factor 39 - - - - 66405 799 9.453333333 8.88 -0.09026345 Down 0.200881944 Mcts2 malignant T cell amplified sequence 2 K07575|1|1e-101|371|cge:100757597|PUA domain protein - - - - 53890 3586 8.553333333 9.126666667 0.093601276 Up 0.200881944 Sart3 squamous cell carcinoma antigen recognized by T cells 3 K11294|1|4e-15|87.0|xla:397919|nucleolin GO:0044424 GO:0097159//organic cyclic compound binding GO:0010467//gene expression gi|8394239|ref|NP_058622.1|/0/squamous cell carcinoma antigen recognized by T-cells 3 [Mus musculus] 67426 3969.79 205.39 197.28 -0.058121237 Down 0.200863139 Adck3 coenzyme Q8A K08869|1|0.0|1170|mmu:67426|aarF domain-containing kinase - - - - 66587 1840 205.1733333 197.2233333 -0.057012988 Down 0.200797322 Fastk Fas-activated serine/threonine kinase K08290|1|0.0|986|mmu:66587|Fas-activated serine/threonine kinase [EC:2.7.11.8] GO:0016604//nuclear body GO:0032550;GO:0004674//protein serine/threonine kinase activity GO:0012501//programmed cell death;GO:0008380//RNA splicing;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process gi|85861160|ref|NP_075718.2|/0/fas-activated serine/threonine kinase [Mus musculus] 18669 4344 1.1 1.296666667 0.237304131 Up 0.200769115 Abcb1b "ATP-binding cassette, sub-family B (MDR/TAP), member 1B" "K05658|1|0.0|2352|mmu:18669|ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:3.6.3.44]" - - - gi|6755046|ref|NP_035205.1|/0/multidrug resistance protein 1B [Mus musculus] 66875 3668 1.133333333 1.336666667 0.23806749 Up 0.200769115 Swt1 SWT1 RNA endoribonuclease homolog (S. cerevisiae) K11124|1|2e-08|64.7|ngi:103730528|protein SMG6 [EC:3.1.-.-] - - - gi|229577364|ref|NP_080095.3|/0/transcriptional protein SWT1 [Mus musculus] 545554 2586 1.143333333 1.346666667 0.236146717 Up 0.200769115 Ankrd34a ankyrin repeat domain 34A K20350|1|5e-32|142|gfr:102036427|p24 family protein gamma-4 GO:0044424 - - gi|120953245|ref|NP_001020022.2|/0/ankyrin repeat domain-containing protein 34A [Mus musculus] 71923 1802 11.98333333 12.71 0.08493476 Up 0.200675091 Borcs6 BLOC-1 related complex subunit 6 K09228|1|6e-29|131|gja:107111210|KRAB domain-containing zinc finger protein - - - gi|120952555|ref|NP_082281.2|/7.6991e-111/uncharacterized protein C17orf59 homolog [Mus musculus] 72084 1019 13.14 13.86666667 0.077655752 Up 0.200675091 Pigx "phosphatidylinositol glycan anchor biosynthesis, class X" "K07541|1|4e-123|443|mmu:72084|phosphatidylinositol glycan, class X" - - - gi|161377440|ref|NP_001104495.1|/6.13792e-121/phosphatidylinositol-glycan biosynthesis class X protein isoform 2 precursor [Mus musculus] 56456 1969 12.03333333 12.76 0.084591993 Up 0.200675091 Actl6a actin-like 6A K11340|1|0.0|878|mmu:56456|actin-like protein 6A GO:0016020//membrane;GO:0090544//BAF-type complex;GO:0043189//H4/H2A histone acetyltransferase complex;GO:0000790//nuclear chromatin GO:0032550;GO:0003712//transcription cofactor activity GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0006259//DNA metabolic process;GO:0007154//cell communication;GO:0044767//single-organism developmental process;GO:0033554//cellular response to stress;GO:0016573//histone acetylation gi|189181668|ref|NP_062647.2|/0/actin-like protein 6A [Mus musculus] 72844 1717.86 13.56333333 12.83333333 -0.079815835 Down 0.200675091 Kctd17 potassium channel tetramerisation domain containing 17 K01011|1|1e-70|270|fch:102052071|thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2];K15074|3|6e-11|71.6|ola:101174920|BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein - - - gi|564360949|ref|XP_006242039.1|/8.46981e-148/PREDICTED: BTB/POZ domain-containing protein KCTD17 isoform X3 [Rattus norvegicus] 73121 1667 0.116666667 0.03 -1.959358016 Down 0.200646884 Fam101a "family with sequence similarity 101, member A" - - - - gi|38348700|ref|NP_082719.1|/3.83266e-101/filamin-interacting protein FAM101A [Mus musculus] 381091 3380 0.033333333 0.126666667 1.925999419 Up 0.200646884 H2-Eb2 "histocompatibility 2, class II antigen E beta2" "K06752|1|1e-104|384|cge:100762240|major histocompatibility complex, class II" - - - - 20717 1668 0.033333333 0.126666667 1.925999419 Up 0.200646884 Serpina3m "serine (or cysteine) peptidase inhibitor, clade A, member 3M" "K04525|1|0.0|764|mmu:20717|serpin peptidase inhibitor, clade A" - - - gi|160333710|ref|NP_033279.2|/0/serine protease inhibitor A3M precursor [Mus musculus] 66689 2854 0.616666667 0.463333333 -0.412440388 Down 0.20059047 Klhl28 kelch-like 28 K10464|1|0.0|1174|mmu:66689|kelch-like protein 28 - - - "gi|148704707|gb|EDL36654.1|/0/BTB (POZ) domain containing 5, isoform CRA_b, partial [Mus musculus]" 100503495 2560 180.7766667 188.1 0.057291372 Up 0.20055286 A930016O22Rik RIKEN cDNA A930016O22 gene K00933|1|5e-51|97.4|hgl:101696521|creatine kinase [EC:2.7.3.2] GO:0044424 GO:0016301//kinase activity;GO:0032550 GO:0006603//phosphocreatine metabolic process gi|6978661|ref|NP_036662.1|/4.56173e-50/creatine kinase M-type [Rattus norvegicus] 15108 938 171.6133333 178.9133333 0.060099261 Up 0.20055286 Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 K08683|1|1e-129|464|mmu:15108|3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178] - - - - 18484 4149 180.2466667 173.2366667 -0.057228262 Down 0.200468239 Pam peptidylglycine alpha-amidating monooxygenase K00504|1|0.0|1784|mmu:18484|peptidylglycine monooxygenase [EC:1.14.17.3];K18200|1|0.0|1784|mmu:18484|peptidylamidoglycolate lyase [EC:4.3.2.5] GO:0030133//transport vesicle;GO:0030141//secretory granule;GO:0031224//intrinsic component of membrane;GO:0043025//neuronal cell body;GO:0042995//cell projection;GO:0044421 "GO:0046914//transition metal ion binding;GO:0016842;GO:0019842//vitamin binding;GO:0019900//kinase binding;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen" GO:0006366//transcription from RNA polymerase II promoter;GO:0043603//cellular amide metabolic process;GO:0007589//body fluid secretion;GO:0009306//protein secretion;GO:0019748//secondary metabolic process;GO:0043627//response to estrogen;GO:0030036//actin cytoskeleton organization;GO:0007565//female pregnancy;GO:0006631//fatty acid metabolic process;GO:0051259//protein oligomerization;GO:0010038//response to metal ion;GO:0009628//response to abiotic stimulus;GO:0009887//organ morphogenesis;GO:0048736;GO:0006464//cellular protein modification process;GO:0031960//response to corticosteroid;GO:0006950//response to stress;GO:0007399//nervous system development;GO:0042698//ovulation cycle gi|153792657|ref|NP_038654.2|/0/peptidyl-glycine alpha-amidating monooxygenase precursor [Mus musculus] 544922 2471 0.486666667 0.64 0.395137942 Up 0.200440032 Zkscan4 zinc finger with KRAB and SCAN domains 4 K09230|1|0.0|1001|mmu:544922|SCAN domain-containing zinc finger protein;K09229|3|0.0|854|cge:100771017|KRAB and SCAN domains-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0048585;GO:0007033//vacuole organization;GO:0006351//transcription, DNA-templated;GO:0006914//autophagy" gi|84993750|ref|NP_001034204.1|/0/zinc finger protein with KRAB and SCAN domains 4 [Mus musculus] 70789 2989.89 0.036666667 0.13 1.8259706 Up 0.200430629 Kynu kynureninase (L-kynurenine hydrolase) K01556|1|1e-165|586|mmu:70789|kynureninase [EC:3.7.1.3] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part "GO:0016823//hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances;GO:0042802//identical protein binding;GO:0043168//anion binding;GO:0016823//hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances;GO:0042802//identical protein binding;GO:0043168//anion binding;GO:0016823//hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances;GO:0042802//identical protein binding;GO:0043168//anion binding" GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0010243//response to organonitrogen compound;GO:0043650;GO:0034097//response to cytokine;GO:0006084//acetyl-CoA metabolic process;GO:0006569//tryptophan catabolic process;GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0010243//response to organonitrogen compound;GO:0043650;GO:0034097//response to cytokine;GO:0006084//acetyl-CoA metabolic process;GO:0006569//tryptophan catabolic process;GO:0019359//nicotinamide nucleotide biosynthetic process;GO:0010243//response to organonitrogen compound;GO:0043650;GO:0034097//response to cytokine;GO:0006084//acetyl-CoA metabolic process;GO:0006569//tryptophan catabolic process gi|575771899|ref|NP_001276522.1|/0/kynureninase isoform 2 [Mus musculus] 18429 555 0.186666667 0.083333333 -1.163498732 Down 0.20035541 Oxt oxytocin K05243|1|5e-62|238|mmu:18429|oxytocin-neurophysin 1 "GO:0033267;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0044421" GO:0005184//neuropeptide hormone activity;GO:0001664//G-protein coupled receptor binding GO:0007631//feeding behavior;GO:0035809;GO:0007416//synapse assembly;GO:0007268//chemical synaptic transmission;GO:0060746//parental behavior;GO:0008016//regulation of heart contraction;GO:0034285;GO:0031667//response to nutrient levels;GO:0019233//sensory perception of pain;GO:0008217//regulation of blood pressure;GO:0043084//penile erection;GO:0001503//ossification;GO:0031960//response to corticosteroid;GO:0007611//learning or memory;GO:0007589//body fluid secretion;GO:0035813//regulation of renal sodium excretion;GO:0034694//response to prostaglandin;GO:0032305//positive regulation of icosanoid secretion;GO:0001696//gastric acid secretion;GO:0046683//response to organophosphorus;GO:0043627//response to estrogen;GO:0002118//aggressive behavior;GO:0006972//hyperosmotic response;GO:0045987//positive regulation of smooth muscle contraction;GO:0044767//single-organism developmental process;GO:0045924//regulation of female receptivity;GO:0007320//insemination;GO:0014061//regulation of norepinephrine secretion;GO:0051480//regulation of cytosolic calcium ion concentration gi|6754960|ref|NP_035155.1|/3.26104e-61/oxytocin-neurophysin 1 preproprotein [Mus musculus] 432628 3125 1.003333333 0.826666667 -0.279423366 Down 0.200336605 Mfsd2b major facilitator superfamily domain containing 2B K08824|1|7e-15|85.9|bfo:BRAFLDRAFT_90694|cyclin-dependent kinase-like [EC:2.7.11.22] - - - gi|74217769|dbj|BAE33602.1|/0/unnamed protein product [Mus musculus] 232539 6571 0.85 1.03 0.277109591 Up 0.200336605 Klhl42 kelch-like 42 K10476|1|1e-34|152|acs:100561412|kelch repeat and BTB domain-containing protein 11 GO:0015630//microtubule cytoskeleton;GO:0031461//cullin-RING ubiquitin ligase complex GO:0005488//binding;GO:0019787//ubiquitin-like protein transferase activity GO:0006511//ubiquitin-dependent protein catabolic process;GO:0000087//mitotic M phase;GO:0016567//protein ubiquitination;GO:0007017//microtubule-based process "gi|148678779|gb|EDL10726.1|/0/mCG7099, partial [Mus musculus]" 110616 5376 1.016666667 0.836666667 -0.281121878 Down 0.200336605 Atxn3 ataxin 3 K11863|1|4e-157|556|mmu:110616|Ataxin-3 [EC:3.4.22.-] GO:0016234//inclusion body;GO:0005740//mitochondrial envelope;GO:0016234//inclusion body;GO:0005740//mitochondrial envelope "GO:0008238//exopeptidase activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0044212//transcription regulatory region DNA binding;GO:0008238//exopeptidase activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0044212//transcription regulatory region DNA binding" "GO:0035967//cellular response to topologically incorrect protein;GO:0007010//cytoskeleton organization;GO:0006351//transcription, DNA-templated;GO:0016579//protein deubiquitination;GO:0016575//histone deacetylation;GO:0030155//regulation of cell adhesion;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0009408//response to heat;GO:0044708//single-organism behavior;GO:0035967//cellular response to topologically incorrect protein;GO:0007010//cytoskeleton organization;GO:0006351//transcription, DNA-templated;GO:0016579//protein deubiquitination;GO:0016575//histone deacetylation;GO:0030155//regulation of cell adhesion;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0009408//response to heat;GO:0044708//single-organism behavior" "gi|29437076|gb|AAH49743.1|/3.77652e-174/Atxn3 protein, partial [Mus musculus]" 19186 977 153.88 160.3466667 0.059388628 Up 0.200280191 Psme1 "proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)" K06696|1|1e-119|431|mmu:19186|proteasome activator subunit 1 (PA28 alpha) GO:0022624//proteasome accessory complex GO:0005488//binding;GO:0061135 GO:0010952//positive regulation of peptidase activity;GO:0019882//antigen processing and presentation gi|667270058|ref|XP_008570561.1|/6.15425e-123/PREDICTED: proteasome activator complex subunit 1 [Galeopterus variegatus] 320046 1551 0.126666667 0.036666667 -1.788495895 Down 0.200242582 F730043M19Rik RIKEN cDNA F730043M19 gene - - - - - 114664 1699 26.61333333 25.43 -0.065617758 Down 0.20019557 Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 K15734|1|9e-71|270|apla:101805250|all-trans-retinol dehydrogenase (NAD+) [EC:1.1.1.105] GO:0044444//cytoplasmic part "GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0006706//steroid catabolic process gi|16716597|ref|NP_444492.1|/2.04296e-158/estradiol 17-beta-dehydrogenase 11 precursor [Mus musculus] 381045 1096 8.81 8.253333333 -0.09416511 Down 0.200148558 Ccdc58 coiled-coil domain containing 58 K16741|1|8e-67|256|bacu:103018416|alstrom syndrome protein 1;K17784|2|1e-05|53.5|loa:LOAG_06147|mitochondrial inner membrane organizing system protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|226874938|ref|NP_001152893.1|/2.79644e-43/coiled-coil domain-containing protein 58 isoform 2 [Mus musculus] 12095 715.18 8.946666667 8.386666667 -0.093252749 Down 0.200148558 Bglap3 bone gamma-carboxyglutamate protein 3 K11546|1|6e-17|89.7|ggo:101142439|polyamine-modulated factor 1 - - - - 18438 2702 8.81 9.366666667 0.088393705 Up 0.200148558 P2rx4 "purinergic receptor P2X, ligand-gated ion channel 4" K05218|1|0.0|719|rno:29659|P2X purinoceptor 4 - - - gi|117676374|ref|NP_035156.2|/0/P2X purinoceptor 4 isoform 1 [Mus musculus] 70252 3802 1.306666667 1.52 0.21818017 Up 0.200129753 Jpx "Jpx transcript, Xist activator (non-protein coding)" - - - - - 66854 3684 25.60333333 24.43 -0.067677785 Down 0.200054534 Trim35 tripartite motif-containing 35 K12012|1|0.0|970|mmu:66854|tripartite motif-containing protein 35 GO:0031981//nuclear lumen GO:0046914//transition metal ion binding GO:0000278//mitotic cell cycle;GO:0008283//cell proliferation;GO:0012502//induction of programmed cell death;GO:0006915//apoptotic process gi|56404889|sp|Q8C006.2|TRI35_MOUSE/0/RecName: Full=Tripartite motif-containing protein 35; AltName: Full=Hemopoietic lineage switch protein 5; AltName: Full=Macrophage-derived apoptosis-inducing RBCC protein; Short=Protein MAIR; AltName: Full=Protein Nc8 107515 5066 4.56 4.196666667 -0.119789947 Down 0.200035729 Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 K04309|1|0.0|1669|mmu:107515|leucine-rich repeat-containing G protein-coupled receptor 4 GO:0031224//intrinsic component of membrane GO:0004930//G-protein coupled receptor activity "GO:0006351//transcription, DNA-templated;GO:0072078//nephron tubule morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0051094//positive regulation of developmental process;GO:0001656//metanephros development;GO:0046546//development of primary male sexual characteristics;GO:0008283//cell proliferation;GO:0032835//glomerulus development" gi|124430559|ref|NP_766259.2|/0/leucine-rich repeat-containing G-protein coupled receptor 4 precursor [Mus musculus] 235441 5594 4.223333333 4.58 0.11696548 Up 0.200035729 Usp3 ubiquitin specific peptidase 3 K11986|1|0.0|855|ggo:101150317|ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin "GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding" GO:0010608//posttranscriptional regulation of gene expression;GO:0006259//DNA metabolic process;GO:0007049//cell cycle;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0016570//histone modification;GO:0010608//posttranscriptional regulation of gene expression;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0016570//histone modification gi|426379399|ref|XP_004056385.1|/0/PREDICTED: ubiquitin carboxyl-terminal hydrolase 3 [Gorilla gorilla gorilla] 104885 2373 4.036666667 4.393333333 0.122151505 Up 0.200035729 Tmem179 transmembrane protein 179 - GO:0031224//intrinsic component of membrane - - gi|125660460|ref|NP_849246.2|/1.16106e-104/transmembrane protein 179 [Mus musculus] 74256 7888.48 3.573333333 3.906666667 0.128667664 Up 0.200016924 Cyld CYLD lysine 63 deubiquitinase K08601|1|0.0|1879|mmu:74256|ubiquitin thioesterase [EC:3.4.19.12] GO:0005874//microtubule;GO:0044444//cytoplasmic part;GO:0030529//intracellular ribonucleoprotein complex;GO:0009898//cytoplasmic side of plasma membrane;GO:0005874//microtubule;GO:0044444//cytoplasmic part;GO:0030529//intracellular ribonucleoprotein complex;GO:0009898//cytoplasmic side of plasma membrane;GO:0005874//microtubule;GO:0044444//cytoplasmic part;GO:0030529//intracellular ribonucleoprotein complex;GO:0009898//cytoplasmic side of plasma membrane;GO:0005874//microtubule;GO:0044444//cytoplasmic part;GO:0030529//intracellular ribonucleoprotein complex;GO:0009898//cytoplasmic side of plasma membrane GO:0046914//transition metal ion binding;GO:0005198//structural molecule activity;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0019900//kinase binding;GO:0046914//transition metal ion binding;GO:0005198//structural molecule activity;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0019900//kinase binding;GO:0046914//transition metal ion binding;GO:0005198//structural molecule activity;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0019900//kinase binding;GO:0046914//transition metal ion binding;GO:0005198//structural molecule activity;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0019900//kinase binding GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0016579//protein deubiquitination;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0030178//negative regulation of Wnt signaling pathway;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0012502//induction of programmed cell death;GO:0019941//modification-dependent protein catabolic process;GO:0097191//extrinsic apoptotic signaling pathway;GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0016579//protein deubiquitination;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0030178//negative regulation of Wnt signaling pathway;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0012502//induction of programmed cell death;GO:0019941//modification-dependent protein catabolic process;GO:0097191//extrinsic apoptotic signaling pathway;GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0016579//protein deubiquitination;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0030178//negative regulation of Wnt signaling pathway;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0012502//induction of programmed cell death;GO:0019941//modification-dependent protein catabolic process;GO:0097191//extrinsic apoptotic signaling pathway;GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0016579//protein deubiquitination;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0030178//negative regulation of Wnt signaling pathway;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0012502//induction of programmed cell death;GO:0019941//modification-dependent protein catabolic process;GO:0097191//extrinsic apoptotic signaling pathway gi|443287660|ref|NP_001263208.1|/0/ubiquitin carboxyl-terminal hydrolase CYLD isoform c [Mus musculus] 19703 1434 3.76 3.433333333 -0.13112273 Down 0.200016924 Renbp renin binding protein K01787|1|0.0|885|mmu:19703|N-acylglucosamine 2-epimerase [EC:5.1.3.8] - "GO:0032550;GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0061135;GO:0042802//identical protein binding;GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses;GO:0000166//nucleotide binding;GO:0032550;GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0061135;GO:0042802//identical protein binding;GO:0016861//intramolecular oxidoreductase activity, interconverting aldoses and ketoses;GO:0000166//nucleotide binding" GO:0019318//hexose metabolic process;GO:0006054//N-acetylneuraminate metabolic process;GO:0006050;GO:1901071;GO:0010466//negative regulation of peptidase activity;GO:0008015//blood circulation;GO:0019318//hexose metabolic process;GO:0006054//N-acetylneuraminate metabolic process;GO:0006050;GO:1901071;GO:0010466//negative regulation of peptidase activity;GO:0008015//blood circulation gi|257796226|ref|NP_001158176.1|/0/N-acylglucosamine 2-epimerase isoform 2 [Mus musculus] 244895 10994 3.786666667 3.453333333 -0.132938832 Down 0.200016924 Peak1 pseudopodium-enriched atypical kinase 1 K17538|1|0.0|3245|mmu:244895|pseudopodium-enriched atypical kinase 1 [EC:2.7.10.2] GO:0005856//cytoskeleton;GO:0005924//cell-substrate adherens junction GO:0032550;GO:0004713//protein tyrosine kinase activity GO:0006468//protein phosphorylation;GO:0048870//cell motility;GO:0000904//cell morphogenesis involved in differentiation gi|157909795|ref|NP_766512.2|/0/pseudopodium-enriched atypical kinase 1 [Mus musculus] 19842 164 3.496666667 3.826666667 0.130107964 Up 0.200016924 Rnu1a1 U1a1 small nuclear RNA K17540|1|8e-25|114|ssc:100737915|inactive serine/threonine-protein kinase TEX14;K06628|2|1e-18|93.6|ocu:103350632|cell division control protein 45;K10393|3|2e-15|83.2|myb:102254543|kinesin family member 2/24 - - - gi|927196956|ref|XP_013836555.1|/7.87342e-24/PREDICTED: inactive serine/threonine-protein kinase TEX14 [Sus scrofa] 227644 4381 3.883333333 3.553333333 -0.128122517 Down 0.200016924 Snapc4 "small nuclear RNA activating complex, polypeptide 4" K09453|1|0.0|2109|mmu:227644|snRNA-activating protein complex subunit 4 GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0005488//binding;GO:0005488//binding GO:0006383//transcription from RNA polymerase III promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006383//transcription from RNA polymerase III promoter;GO:0006366//transcription from RNA polymerase II promoter "gi|148676357|gb|EDL08304.1|/0/small nuclear RNA activating complex, polypeptide 4, isoform CRA_b, partial [Mus musculus]" 77048 3006 3.97 3.64 -0.125200557 Down 0.200016924 Cep83 centrosomal protein 83 K16754|1|0.0|1265|mmu:77048|coiled-coil domain-containing protein 41 - - - gi|27229249|ref|NP_084128.2|/0/centrosomal protein of 83 kDa [Mus musculus] 14588 1430 3.89 3.56 -0.127892914 Down 0.200016924 Gfra4 glial cell line derived neurotrophic factor family receptor alpha 4 K19895|1|1e-46|189|amj:102573225|GDNF family receptor alpha 1 GO:0044421;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0031224//intrinsic component of membrane GO:0004896//cytokine receptor activity;GO:0004896//cytokine receptor activity;GO:0004896//cytokine receptor activity;GO:0004896//cytokine receptor activity GO:0001503//ossification;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001503//ossification;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001503//ossification;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001503//ossification;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|9910240|ref|NP_064398.1|/8.26769e-158/GDNF family receptor alpha-4 isoform 2 [Mus musculus] 353169 3762 3.833333333 3.5 -0.131244533 Down 0.200016924 Slc2a12 "solute carrier family 2 (facilitated glucose transporter), member 12" "K08149|1|0.0|1118|mmu:353169|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 12" GO:0031224//intrinsic component of membrane GO:0022857//transmembrane transporter activity GO:0008645//hexose transport;GO:0044763 "gi|226437623|ref|NP_849265.2|/0/solute carrier family 2, facilitated glucose transporter member 12 [Mus musculus]" 97761 4791 3.573333333 3.9 0.126203624 Up 0.200016924 Sgsm2 small G protein signaling modulator 2 K20168|1|2e-31|141|tad:TRIADDRAFT_38489|TBC1 domain family member 15 GO:0044464 - - gi|28972203|dbj|BAC65555.1|/0/mKIAA0397 protein [Mus musculus] 17904 692.82 158.0933333 152.1566667 -0.055218986 Down 0.199969912 Myl6 "myosin, light polypeptide 6, alkali, smooth muscle and non-muscle" K12751|1|8e-83|308|myb:102260238|myosin light chain 6 - - - - 241066 5596.68 0.863333333 0.696666667 -0.309449156 Down 0.19996051 Carf calcium response factor - GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|987937204|ref|XP_015416588.1|/0/PREDICTED: calcium-responsive transcription factor isoform X1 [Myotis davidii] 68268 8751 0.863333333 0.696666667 -0.309449156 Down 0.19996051 Zdhhc21 "zinc finger, DHHC domain containing 21" K18932|1|2e-151|541|mmu:68268|palmitoyltransferase [EC:2.3.1.225] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle "GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0046914//transition metal ion binding" GO:0008544//epidermis development;GO:0048732//gland development;GO:0018231;GO:0006497//protein lipidation gi|989984194|ref|XP_015450021.1|/3.50482e-167/PREDICTED: palmitoyltransferase ZDHHC21 isoform X1 [Pteropus alecto] 76223 2619.5 0.606666667 0.766666667 0.337695411 Up 0.199913498 Agbl3 ATP/GTP binding protein-like 3 K05840|1|4e-15|87.4|myb:102243447|dopamine receptor D5;K04257|2|1e-12|79.0|shr:100920260|olfactory receptor GO:0044424;GO:0044424 GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process gi|576067885|ref|NP_001276587.1|/4.25042e-49/cytosolic carboxypeptidase 3 isoform 4 [Mus musculus] 13543 2937 2.306666667 2.576666667 0.159696376 Up 0.199866486 Dvl2 dishevelled segment polarity protein 2 K02353|1|0.0|1014|mmu:13543|segment polarity protein dishevelled - - - - 232286 6781 2.523333333 2.253333333 -0.163270054 Down 0.199866486 Tmf1 TATA element modulatory factor 1 K20286|1|0.0|1627|mmu:232286|TATA element modulatory factor GO:0043231//intracellular membrane-bounded organelle - GO:0006952//defense response;GO:0048870//cell motility;GO:0014070//response to organic cyclic compound;GO:0006997//nucleus organization;GO:0007281//germ cell development;GO:0010467//gene expression;GO:0008406//gonad development;GO:0001816//cytokine production gi|124487429|ref|NP_001074580.1|/0/TATA element modulatory factor [Mus musculus] 623661 1555 6.503333333 6.056666667 -0.102655358 Down 0.199819474 Lipt1 lipoyltransferase 1 K10105|1|0.0|776|mmu:623661|lipoyltransferase 1 - - - - 57439 3169 4.993333333 5.396666667 0.112065362 Up 0.199810072 Tmem183a transmembrane protein 183A K11824|1|2e-48|197|sko:102810292|AP-2 complex subunit alpha GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148707669|gb|EDL39616.1|/0/RIKEN cDNA 1300007B12, isoform CRA_a, partial [Mus musculus]" 74030 4668 5.093333333 5.493333333 0.109071699 Up 0.199810072 Rin2 Ras and Rab interactor 2 K17638|1|3e-67|260|xtr:100495483|Ras and Rab interactor 1 - - - - 381626 9501 5.59 5.19 -0.107113744 Down 0.199810072 Rbm33 RNA binding motif protein 33 K14007|1|8e-06|57.4|dya:Dyak_GE15184|protein transport protein SEC24 - - - gi|568933234|ref|XP_006535797.1|/0/PREDICTED: RNA-binding protein 33 isoform X2 [Mus musculus] 66092 2915.63 130.73 125.1833333 -0.062547752 Down 0.199744255 Ghitm growth hormone inducible transmembrane protein - GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding GO:0012501//programmed cell death;GO:0012501//programmed cell death gi|74195753|dbj|BAE30441.1|/0/unnamed protein product [Mus musculus] 380842 1384 0.043333333 0.133333333 1.621488377 Up 0.199734853 Stmnd1 stathmin domain containing 1 - - - - gi|53749206|ref|NP_001005422.1|/3.83934e-133/stathmin domain-containing protein 1 [Mus musculus] 67938 939 135.33 129.8266667 -0.059894946 Down 0.19972545 Myl12b "myosin, light chain 12B, regulatory" K12757|1|1e-84|315|shr:100920097|myosin regulatory light chain 12 GO:0016459//myosin complex;GO:0031674//I band;GO:0032432//actin filament bundle GO:0046872//metal ion binding;GO:0005102//receptor binding GO:0022604//regulation of cell morphogenesis;GO:0003012//muscle system process;GO:0006935//chemotaxis;GO:0006612//protein targeting to membrane gi|884882468|ref|XP_013002153.1|/1.17538e-83/PREDICTED: myosin regulatory light chain 12B-like isoform X1 [Cavia porcellus] 54405 516 139.72 145.22 0.05570161 Up 0.19972545 Ndufa1 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1" K03945|1|2e-41|170|rno:103694507|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1 GO:0031224//intrinsic component of membrane;GO:0005746//mitochondrial respiratory chain - GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy gi|672088463|ref|XP_008771711.1|/1.12304e-40/PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 [Rattus norvegicus] 218035 3212 12.13666667 12.85 0.082396119 Up 0.199687841 Vps41 VPS41 HOPS complex subunit K20184|1|0.0|1682|mmu:218035|vacuolar protein sorting-associated protein 41 "GO:0015630//microtubule cytoskeleton;GO:0005768//endosome;GO:0005774//vacuolar membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0046914//transition metal ion binding;GO:0015631//tubulin binding GO:0016192//vesicle-mediated transport;GO:0015031//protein transport "gi|148700761|gb|EDL32708.1|/0/vacuolar protein sorting 41 (yeast), isoform CRA_c, partial [Mus musculus]" 20787 4347 13.23666667 12.52333333 -0.079921245 Down 0.199687841 Srebf1 sterol regulatory element binding transcription factor 1 K07197|1|0.0|1838|mmu:20787|sterol regulatory element-binding transcription factor 1 - - - - 75459 478 0.223333333 0.113333333 -0.978626349 Down 0.199678438 Syce3 synaptonemal complex central element protein 3 K19536|1|1e-34|147|rno:689933|synaptonemal complex central element protein 3 - - - - 102634473 881 0.23 0.12 -0.938599455 Down 0.199678438 Gm29669 predicted gene 29669 - - - - - 101835 3411 0.513333333 0.373333333 -0.459431619 Down 0.199650231 AW146154 expressed sequence AW146154 K09228|1|0.0|1034|mmu:101835|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|85702035|ref|NP_001028702.1|/0/uncharacterized protein LOC101835 [Mus musculus] 17932 5305 0.09 0.193333333 1.103093493 Up 0.199612622 Myt1 myelin transcription factor 1 K11307|1|3e-06|58.2|aqu:100638592|histone acetyltransferase MYST2 [EC:2.3.1.48] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0048869//cellular developmental process;GO:0048731//system development;GO:0006351//transcription, DNA-templated;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0006351//transcription, DNA-templated;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0006351//transcription, DNA-templated;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0006351//transcription, DNA-templated" gi|49022813|dbj|BAC41451.2|/0/mKIAA0835 protein [Mus musculus] 19182 1651 127.6633333 133.0333333 0.059443555 Up 0.199584415 Psmc3 "proteasome (prosome, macropain) 26S subunit, ATPase 3" K03065|1|0.0|867|mmu:19182|26S proteasome regulatory subunit T5 GO:0031981//nuclear lumen;GO:0035770//ribonucleoprotein granule;GO:0000502//proteasome complex;GO:0044444//cytoplasmic part GO:0016462//pyrophosphatase activity;GO:0032550;GO:0003712//transcription cofactor activity "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0006915//apoptotic process;GO:0051320;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0001701//in utero embryonic development" gi|74185161|dbj|BAE39181.1|/0/unnamed protein product [Mus musculus] 18534 2617 0.293333333 0.176666667 -0.731511164 Down 0.19956561 Pck1 "phosphoenolpyruvate carboxykinase 1, cytosolic" K01596|1|0.0|1269|mmu:18534|phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] GO:0044444//cytoplasmic part "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0032550;GO:0043168//anion binding;GO:0004611//phosphoenolpyruvate carboxykinase activity;GO:0046914//transition metal ion binding;GO:0000166//nucleotide binding" GO:0043648//dicarboxylic acid metabolic process;GO:0006473//protein acetylation;GO:0006090//pyruvate metabolic process;GO:0043434//response to peptide hormone;GO:0006796//phosphate-containing compound metabolic process;GO:0006006//glucose metabolic process;GO:0033500//carbohydrate homeostasis "gi|7110683|ref|NP_035174.1|/0/phosphoenolpyruvate carboxykinase, cytosolic [GTP] [Mus musculus]" 100041546 875 8.14 8.693333333 0.094880669 Up 0.199509196 Ly6c2 "lymphocyte antigen 6 complex, locus C2" K06846|1|2e-60|234|mmu:17067|lymphocyte antigen 6 complex locus protein D/E/G6/H GO:0009986//cell surface;GO:0031224//intrinsic component of membrane - - gi|149773537|ref|NP_001092687.1|/3.84815e-62/lymphocyte antigen 6C2 precursor [Mus musculus] 14225 1673.45 118.7733333 124.0166667 0.062323056 Up 0.199499793 Fkbp1a FK506 binding protein 1a K09568|1|1e-56|223|mmu:14225|FK506-binding protein 1 [EC:5.2.1.8] - - - gi|689972373|ref|NP_001289007.1|/8.01897e-82/peptidyl-prolyl cis-trans isomerase FKBP1A isoform 2 [Mus musculus] 13732 760.53 13.42666667 12.72666667 -0.077246581 Down 0.199339953 Emp3 epithelial membrane protein 3 K19289|1|2e-26|121|cmk:103175419|peripheral myelin protein 22 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0040007//growth;GO:0040007//growth gi|226437637|ref|NP_034259.2|/2.91396e-70/epithelial membrane protein 3 [Mus musculus] 218460 3069 12.61666667 13.32 0.078263283 Up 0.199339953 Wdr41 WD repeat domain 41 K10260|1|5e-10|69.7|tad:TRIADDRAFT_30121|F-box and WD-40 domain protein 7;K11798|4|1e-08|65.1|crg:105317194|bromodomain and WD repeat domain containing protein 1/3 - - - - 68545 1111 12.5 11.8 -0.083141235 Down 0.199339953 Ecscr endothelial cell surface expressed chemotaxis and apoptosis regulator - - - - gi|75677530|ref|NP_001028313.1|/4.82441e-85/endothelial cell-specific chemotaxis regulator [Mus musculus] 76014 3756.71 12.69 11.99333333 -0.081459383 Down 0.199339953 Zc3h18 zinc finger CCCH-type containing 18 K13092|1|7e-166|587|mmu:76014|nuclear protein NHN1 GO:0005634//nucleus GO:0005488//binding - gi|537194535|gb|ERE77819.1|/0/zinc finger CCCH domain-containing protein 18 isoform 2 [Cricetulus griseus] 213452 6385 3.153333333 2.853333333 -0.144229387 Down 0.199264734 Dstyk dual serine/threonine and tyrosine protein kinase K16288|1|0.0|1709|mmu:213452|receptor-interacting serine/threonine-protein kinase 5 [EC:2.7.11.1] GO:0005856//cytoskeleton;GO:0031981//nuclear lumen GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|40556610|ref|NP_766104.2|/0/dual serine/threonine and tyrosine protein kinase [Mus musculus] 235682 6189 2.88 3.18 0.142957954 Up 0.199264734 Zfp445 zinc finger protein 445 K09229|1|0.0|1993|mmu:235682|KRAB and SCAN domains-containing zinc finger protein GO:0005622//intracellular GO:0046872//metal ion binding "GO:0006351//transcription, DNA-templated" gi|257096022|ref|NP_775540.4|/0/zinc finger protein 445 [Mus musculus] 12160 3827 2.953333333 3.256666667 0.141051863 Up 0.199264734 Bmp5 bone morphogenetic protein 5 K04663|1|0.0|905|mmu:12160|bone morphogenetic protein 5 - - - - 18521 2822.84 126.2733333 131.2566667 0.055840701 Up 0.199255331 Pcbp2 poly(rC) binding protein 2 K13162|1|0.0|687|bta:540653|poly(rC)-binding protein 2/3/4 GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003676//nucleic acid binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003676//nucleic acid binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003676//nucleic acid binding;GO:0044389//ubiquitin-like protein ligase binding GO:0006952//defense response;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0002698;GO:0000377;GO:0001818//negative regulation of cytokine production;GO:0006952//defense response;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0002698;GO:0000377;GO:0001818//negative regulation of cytokine production;GO:0006952//defense response;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0002698;GO:0000377;GO:0001818//negative regulation of cytokine production;GO:0006952//defense response;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0002698;GO:0000377;GO:0001818//negative regulation of cytokine production gi|77736367|ref|NP_001029883.1|/0/poly(rC)-binding protein 2 [Bos taurus] 11856 4369.09 0.973333333 1.16 0.253118937 Up 0.199208319 Arhgap6 Rho GTPase activating protein 6 "K18470|1|4e-19|100|apla:101793383|Rho GTPase-activating protein 1;K18439|5|9e-18|95.9|aqu:100639879|Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1" - - - - 18011 3690 1.206666667 1.013333333 -0.251918374 Down 0.199208319 Neurl1a neuralized E3 ubiquitin protein ligase 1A K01931|1|0.0|1078|mmu:18011|protein neuralized [EC:2.3.2.27] - - - - 319615 2784 0.9 0.733333333 -0.295455884 Down 0.199142503 Zfp944 zinc finger protein 944 K09228|1|0.0|1085|mmu:319615|KRAB domain-containing zinc finger protein - - - "gi|148673819|gb|EDL05766.1|/0/mCG23334, isoform CRA_b [Mus musculus]" 100038752 4548 0.746666667 0.916666667 0.295932886 Up 0.199142503 Gm10825 predicted gene 10825 - - - - gi|74201720|dbj|BAE28472.1|/2.82849e-36/unnamed protein product [Mus musculus] 11567 3033 0.193333333 0.313333333 0.696607857 Up 0.199123698 Avil advillin K08017|1|0.0|1661|mmu:11567|advillin GO:0043005//neuron projection;GO:0043232 GO:0008092//cytoskeletal protein binding GO:0050896//response to stimulus;GO:0048858//cell projection morphogenesis;GO:0030835//negative regulation of actin filament depolymerization;GO:0010975//regulation of neuron projection development gi|568966420|ref|XP_006513165.1|/0/PREDICTED: advillin isoform X3 [Mus musculus] 26445 861 113.7666667 118.52 0.059052618 Up 0.199057881 Psmb2 "proteasome (prosome, macropain) subunit, beta type 2" K02734|1|1e-101|371|cjc:100385354|20S proteasome subunit beta 4 [EC:3.4.25.1] GO:0031981//nuclear lumen;GO:0000502//proteasome complex;GO:0044444//cytoplasmic part GO:0004175//endopeptidase activity "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0010033//response to organic substance;GO:0006915//apoptotic process;GO:0051320;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0009719" gi|675669600|ref|XP_002750652.2|/1.18312e-100/PREDICTED: proteasome subunit beta type-2 [Callithrix jacchus] 75479 629 0.653333333 0.503333333 -0.376305105 Down 0.199039076 1700012D14Rik RIKEN cDNA 1700012D14 gene - - - - - 68480 804 102.8133333 107.52 0.064577671 Up 0.199029674 Card19 "caspase recruitment domain family, member 19" - - - - - 100043766 2136 1.07 0.886666667 -0.271147052 Down 0.199020272 Gm14057 Ppp1r14c pseudogene K17556|1|2e-43|174|mmu:76142|protein phosphatase 1 regulatory subunit 14C - - - - 229613 2828 0.09 0.19 1.078002512 Up 0.199001467 6330549D23Rik RIKEN cDNA 6330549D23 gene - - - - - 70574 5195 2.833333333 2.556666667 -0.148236264 Down 0.198982662 Cpm carboxypeptidase M K01296|1|0.0|925|mmu:70574|carboxypeptidase M [EC:3.4.17.12] GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding GO:0019538//protein metabolic process;GO:0032502//developmental process "gi|28958152|gb|AAH47389.1|/0/Cpm protein, partial [Mus musculus]" 73225 2560 2.45 2.726666667 0.154356593 Up 0.198982662 Fam118a "family with sequence similarity 118, member A" - GO:0031224//intrinsic component of membrane - - gi|568993513|ref|XP_006521545.1|/0/PREDICTED: protein FAM118A isoform X6 [Mus musculus] 22032 3016 2.503333333 2.78 0.151234476 Up 0.198982662 Traf4 TNF receptor associated factor 4 K09848|1|0.0|972|mmu:22032|TNF receptor-associated factor 4 GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0043232 GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0019904//protein domain specific binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0019900//kinase binding GO:0032092//positive regulation of protein binding;GO:0006915//apoptotic process;GO:0032147//activation of protein kinase activity;GO:0007254//JNK cascade;GO:0035295//tube development;GO:0032446//protein modification by small protein conjugation gi|31543889|ref|NP_033449.2|/0/TNF receptor-associated factor 4 [Mus musculus] 22249 6423 2.19 1.943333333 -0.172397487 Down 0.198954455 Unc13b unc-13 homolog B (C. elegans) K15293|1|0.0|3133|mmu:22249|protein unc-13 A/B/C GO:0045202//synapse;GO:0016020//membrane GO:0043169//cation binding;GO:0008289//lipid binding GO:0016079//synaptic vesicle exocytosis;GO:0048741//skeletal muscle fiber development;GO:0021675//nerve development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0007270//neuron-neuron synaptic transmission;GO:0007165//signal transduction;GO:0006904//vesicle docking involved in exocytosis gi|894216151|ref|NP_001297687.1|/0/protein unc-13 homolog B isoform 3 [Mus musculus] 12504 3095 0.393333333 0.536666667 0.448273829 Up 0.19893565 Cd4 CD4 antigen K06454|1|0.0|778|mmu:12504|CD4 antigen GO:0044432;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0019900//kinase binding GO:0001934//positive regulation of protein phosphorylation;GO:0034613//cellular protein localization;GO:0006497//protein lipidation;GO:0042742//defense response to bacterium;GO:0042110//T cell activation;GO:0022610;GO:0019048//modulation by virus of host morphology or physiology;GO:0019722//calcium-mediated signaling;GO:0030098//lymphocyte differentiation gi|7304953|ref|NP_038516.1|/0/T-cell surface glycoprotein CD4 precursor [Mus musculus] 18968 5350 0.53 0.386666667 -0.45490196 Down 0.19893565 Pola1 "polymerase (DNA directed), alpha 1" K02320|1|0.0|2801|mmu:18968|DNA polymerase alpha subunit A [EC:2.7.7.7] - - - gi|6679409|ref|NP_032918.1|/0/DNA polymerase alpha catalytic subunit [Mus musculus] 57437 1858.02 21.83 22.94666667 0.071972466 Up 0.198907443 Golga7 "golgi autoantigen, golgin subfamily a, 7" "K11728|1|3e-25|119|smm:Smp_129330|nucleosome-remodeling factor subunit BPTF;K05546|2|2e-22|110|tsp:Tsp_01492|alpha 1,3-glucosidase [EC:3.2.1.84]" GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle - GO:0006892//post-Golgi vesicle-mediated transport;GO:0006892//post-Golgi vesicle-mediated transport gi|7634777|gb|AAF65180.1|AF068291_1/8.98936e-75/HDCKB03P [Homo sapiens] 229096 5178.91 8.676666667 8.133333333 -0.093294164 Down 0.198879236 Ythdf3 YTH domain family 3 K20102|1|0.0|838|phd:102336490|YTH domain-containing family protein - GO:0005488//binding;GO:0005488//binding - gi|225543497|ref|NP_001139391.1|/0/YTH domain-containing family protein 3 isoform 2 [Mus musculus] 17973 2396.2 8.776666667 9.316666667 0.086140762 Up 0.198879236 Nck1 non-catalytic region of tyrosine kinase adaptor protein 1 K07365|1|0.0|762|cge:100769675|NCK adaptor protein 1 - - - - 100504628 546 0.193333333 0.096666667 -1 Down 0.198794614 Gm20319 "predicted gene, 20319" K04723|1|1e-60|233|mmu:16180|interleukin 1 receptor accessory protein GO:0032991//macromolecular complex;GO:0016021//integral component of membrane;GO:0044424 GO:0005126//cytokine receptor binding;GO:0004896//cytokine receptor activity;GO:0019838//growth factor binding GO:0006952//defense response;GO:0032623//interleukin-2 production;GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway;GO:0065003 "gi|148665276|gb|EDK97692.1|/1.0079e-59/interleukin 1 receptor accessory protein, isoform CRA_c, partial [Mus musculus]" 19733 1574 0.1 0.203333333 1.023846742 Up 0.198794614 Rgn regucalcin K01053|1|6e-175|616|mmu:19733|gluconolactonase [EC:3.1.1.17] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0052689//carboxylic ester hydrolase activity GO:0019852//L-ascorbic acid metabolic process;GO:0043462//regulation of ATPase activity;GO:0006875//cellular metal ion homeostasis;GO:0019722//calcium-mediated signaling gi|6677739|ref|NP_033086.1|/5.35081e-174/regucalcin [Mus musculus] 268448 4412 13.20333333 12.51 -0.077820411 Down 0.198794614 Phf12 PHD finger protein 12 K10603|1|1e-12|79.0|xtr:100497732|autoimmune regulator;K11655|2|8e-12|76.3|spu:577837|bromodomain adjacent to zinc finger domain protein 1A;K14435|4|2e-11|74.7|clv:102085714|chromodomain-helicase-DNA-binding protein 5 [EC:3.6.4.12] GO:0070822//Sin3-type complex GO:0046914//transition metal ion binding;GO:0005543//phospholipid binding;GO:0001221//transcription cofactor binding;GO:0001104//RNA polymerase II transcription cofactor activity "GO:0006351//transcription, DNA-templated" gi|198442868|ref|NP_777277.2|/0/PHD finger protein 12 [Mus musculus] 20418 1540 0.193333333 0.093333333 -1.050626073 Down 0.198794614 Shc3 src homology 2 domain-containing transforming protein C3 K17448|1|0.0|966|mmu:20418|SHC-transforming protein 3 GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0060089;GO:0005515//protein binding GO:0007264//small GTPase mediated signal transduction;GO:0038127//ERBB signaling pathway;GO:0007399//nervous system development;GO:0007270//neuron-neuron synaptic transmission;GO:0044708//single-organism behavior gi|148709153|gb|EDL41099.1|/0/src homology 2 domain-containing transforming protein C3 [Mus musculus] 260305 5047 0.193333333 0.096666667 -1 Down 0.198794614 Nphp4 nephronophthisis 4 (juvenile) homolog (human) K16478|1|0.0|2684|mmu:260305|nephrocystin-4 GO:0043296//apical junction complex;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle - GO:0043010//camera-type eye development gi|124244073|ref|NP_700473.2|/0/nephrocystin-4 [Mus musculus] 19362 1835 0.79 0.626666667 -0.334154397 Down 0.198785212 Rad51ap1 RAD51 associated protein 1 - GO:0043231//intracellular membrane-bounded organelle GO:0043566//structure-specific DNA binding GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress gi|110626102|ref|NP_033039.2|/4.13355e-152/RAD51-associated protein 1 [Mus musculus] 14368 4086.98 6.35 5.91 -0.103598461 Down 0.198719395 Fzd6 frizzled class receptor 6 K02376|1|0.0|1364|mmu:14368|frizzled 6 - - - - 70427 2631 6.033333333 6.476666667 0.102296204 Up 0.198719395 Mier2 MIER family member 2 K11829|1|1e-08|65.1|ssc:100155804|REST corepressor 1;K11660|2|1e-08|64.7|lcm:102358904|metastasis-associated protein MTA GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|940516976|ref|NP_001303628.1|/0/mesoderm induction early response protein 2 isoform 1 [Mus musculus] 76709 1597 98.52666667 102.9233333 0.062983933 Up 0.198709993 Arpc2 "actin related protein 2/3 complex, subunit 2" "K05758|1|5e-169|596|mmu:76709|actin related protein 2/3 complex, subunit 2" GO:0043231//intracellular membrane-bounded organelle;GO:0005924//cell-substrate adherens junction;GO:0015629//actin cytoskeleton;GO:0016020//membrane GO:0008092//cytoskeletal protein binding;GO:0032403//protein complex binding;GO:0005198//structural molecule activity GO:0010770//positive regulation of cell morphogenesis involved in differentiation;GO:0030041//actin filament polymerization;GO:0008064//regulation of actin polymerization or depolymerization gi|74195800|dbj|BAE30463.1|/0/unnamed protein product [Mus musculus] 69863 8764 1.663333333 1.893333333 0.186851114 Up 0.198681786 Ttc39b tetratricopeptide repeat domain 39B - - - - gi|58037187|ref|NP_081514.1|/0/tetratricopeptide repeat protein 39B [Mus musculus] 101685 5240 1.87 1.636666667 -0.192277746 Down 0.198681786 Spty2d1 "SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)" K15193|1|0.0|868|mmu:101685|protein SPT2 - - - gi|51592080|ref|NP_780527.2|/0/protein SPT2 homolog [Mus musculus] 74718 2669 1.823333333 1.596666667 -0.191515177 Down 0.198681786 Snx16 sorting nexin 16 K17928|1|0.0|651|mmu:74718|sorting nexin-16 GO:0005769//early endosome;GO:0000323//lytic vacuole;GO:0005770//late endosome;GO:0010008//endosome membrane;GO:0005769//early endosome;GO:0000323//lytic vacuole;GO:0005770//late endosome;GO:0010008//endosome membrane GO:0005543//phospholipid binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005515//protein binding GO:0007041//lysosomal transport;GO:0006623//protein targeting to vacuole;GO:0016192//vesicle-mediated transport;GO:0007041//lysosomal transport;GO:0006623//protein targeting to vacuole;GO:0016192//vesicle-mediated transport gi|187831285|ref|NP_083344.3|/0/sorting nexin-16 isoform a [Mus musculus] 64817 11275 1.67 1.903333333 0.188680142 Up 0.198681786 Svep1 "sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1" K17495|1|0.0|7440|mmu:64817|CUB and sushi domain-containing protein - - - - 68222 1130 22.33 23.43333333 0.069578937 Up 0.198465531 Fam166a "family with sequence similarity 166, member A" - - - - gi|21311859|ref|NP_080900.1|/0/protein FAM166A [Mus musculus] 407786 2540 4.513333333 4.16 -0.117609805 Down 0.198437324 Taf9b TATA-box binding protein associated factor 9B K03133|1|3e-113|412|mmu:407786|transcription initiation factor TFIID subunit 9B GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0046983//protein dimerization activity;GO:0046983//protein dimerization activity GO:0016049//cell growth;GO:0006915//apoptotic process;GO:0010033//response to organic substance;GO:0006366//transcription from RNA polymerase II promoter;GO:0016049//cell growth;GO:0006915//apoptotic process;GO:0010033//response to organic substance;GO:0006366//transcription from RNA polymerase II promoter gi|269784727|ref|NP_001161460.1|/5.05776e-138/transcription initiation factor TFIID subunit 9B isoform 1 [Mus musculus] 68614 2579 4.09 4.443333333 0.119541531 Up 0.198437324 Letmd1 LETM1 domain containing 1 "K17800|1|2e-08|63.9|mze:101475753|LETM1 and EF-hand domain-containing protein 1, mitochondrial" GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane - - gi|19527322|ref|NP_598854.1|/0/LETM1 domain-containing protein 1 [Mus musculus] 75939 2004 3.99 4.34 0.121306296 Up 0.198437324 4930579G24Rik RIKEN cDNA 4930579G24 gene "K03847|1|6e-06|39.3|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - gi|254692981|ref|NP_083758.1|/5.82382e-38/uncharacterized protein C4orf46 homolog [Mus musculus] 56357 2067 104.18 108.3066667 0.056043707 Up 0.198418519 Ivd isovaleryl coenzyme A dehydrogenase K00253|1|0.0|811|mmu:56357|isovaleryl-CoA dehydrogenase [EC:1.3.8.4] GO:0005740//mitochondrial envelope GO:0003995//acyl-CoA dehydrogenase activity;GO:0000166//nucleotide binding GO:0006551//leucine metabolic process;GO:0051259//protein oligomerization;GO:0006635//fatty acid beta-oxidation;GO:0009063//cellular amino acid catabolic process "gi|9789985|ref|NP_062800.1|/0/isovaleryl-CoA dehydrogenase, mitochondrial precursor [Mus musculus]" 53975 2710 4.863333333 5.25 0.110371945 Up 0.198380909 Ddx20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 K13131|1|0.0|1502|mmu:53975|ATP-dependent RNA helicase DDX20 [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0030529//intracellular ribonucleoprotein complex "GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0005515//protein binding" "GO:0012502//induction of programmed cell death;GO:0006396//RNA processing;GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated" gi|148540073|ref|NP_059093.3|/0/probable ATP-dependent RNA helicase DDX20 [Mus musculus] 100910 3730 5.256666667 4.866666667 -0.111214291 Down 0.198380909 Chpf2 chondroitin polymerizing factor 2 K03419|1|0.0|1292|mmu:100910|chondroitin polymerizing factor 2 [EC:2.4.1.226] GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane GO:0015020//glucuronosyltransferase activity GO:0006024//glycosaminoglycan biosynthetic process;GO:0044238//primary metabolic process;GO:0006790//sulfur compound metabolic process gi|28972740|dbj|BAC65786.1|/0/mKIAA1402 protein [Mus musculus] 69718 5432 3.623333333 3.303333333 -0.133394978 Down 0.198362105 Ipmk inositol polyphosphate multikinase K00915|1|0.0|787|mmu:69718|inositol-polyphosphate multikinase [EC:2.7.1.140 2.7.1.151] GO:0031981//nuclear lumen GO:0051766//inositol trisphosphate kinase activity;GO:0032550;GO:0051765//inositol tetrakisphosphate kinase activity GO:0046488//phosphatidylinositol metabolic process;GO:0001838//embryonic epithelial tube formation;GO:0043647//inositol phosphate metabolic process gi|58037171|ref|NP_081460.1|/0/inositol polyphosphate multikinase [Mus musculus] 246179 3382 3.466666667 3.79 0.128648726 Up 0.198362105 Fktn fukutin K19872|1|0.0|937|mmu:246179|fukutin [EC:2.-.-.-] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0044421 GO:0003824//catalytic activity GO:0007254//JNK cascade;GO:0006486//protein glycosylation;GO:0048513//animal organ development;GO:0008283//cell proliferation gi|568926734|ref|XP_006538004.1|/0/PREDICTED: fukutin isoform X1 [Mus musculus] 212555 2047 3.366666667 3.686666667 0.130996093 Up 0.198362105 Pqlc2 PQ loop repeat containing 2 K05543|1|1e-35|154|tsp:Tsp_01302|tRNA-dihydrouridine synthase 2 [EC:1.3.1.91];K03247|2|3e-21|106|smm:Smp_158500|translation initiation factor 3 subunit H GO:0005764//lysosome;GO:0016021//integral component of membrane GO:0008324//cation transmembrane transporter activity GO:0055081//anion homeostasis;GO:0046942//carboxylic acid transport;GO:0006812//cation transport gi|564353684|ref|XP_006239300.1|/6.60942e-154/PREDICTED: lysosomal amino acid transporter 1 homolog isoform X1 [Rattus norvegicus] 224454 3115 3.27 3.59 0.134693208 Up 0.198362105 Zdhhc14 "zinc finger, DHHC domain containing 14" K16675|1|0.0|956|mmu:224454|palmitoyltransferase ZDHHC9/14/18 [EC:2.3.1.225] GO:0031224//intrinsic component of membrane GO:0016740//transferase activity;GO:0046914//transition metal ion binding - "gi|148669711|gb|EDL01658.1|/0/zinc finger, DHHC domain containing 14, isoform CRA_b, partial [Mus musculus]" 20429 3099.39 0.133333333 0.246666667 0.887525271 Up 0.19830569 Shox2 short stature homeobox 2 K09331|1|8e-75|283|ecb:100056121|short stature homeobox protein GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding GO:0003206//cardiac chamber morphogenesis;GO:0002062//chondrocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007409//axonogenesis;GO:0010720//positive regulation of cell development;GO:0001503//ossification;GO:0030326//embryonic limb morphogenesis;GO:0048644//muscle organ morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0007224//smoothened signaling pathway;GO:0048546//digestive tract morphogenesis;GO:0051960//regulation of nervous system development;GO:0048704//embryonic skeletal system morphogenesis;GO:0003206//cardiac chamber morphogenesis;GO:0002062//chondrocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007409//axonogenesis;GO:0010720//positive regulation of cell development;GO:0001503//ossification;GO:0030326//embryonic limb morphogenesis;GO:0048644//muscle organ morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0007224//smoothened signaling pathway;GO:0048546//digestive tract morphogenesis;GO:0051960//regulation of nervous system development;GO:0048704//embryonic skeletal system morphogenesis gi|697272082|ref|NP_001289286.1|/1.99365e-115/short stature homeobox protein 2 isoform 2 [Mus musculus] 78102 823 0.13 0.243333333 0.90442234 Up 0.19830569 8430426J06Rik RIKEN cDNA 8430426J06 gene - - - - "gi|148672637|gb|EDL04584.1|/1.72774e-20/mCG1027791, isoform CRA_a [Mus musculus]" 67095 4914 93.25 89.26 -0.063089919 Down 0.198268081 Trak1 "trafficking protein, kinesin binding 1" K15369|1|0.0|1740|mmu:67095|trafficking kinesin-binding protein 1 GO:0005768//endosome GO:0005102//receptor binding GO:0007041//lysosomal transport gi|124517685|ref|NP_780323.2|/0/trafficking kinesin-binding protein 1 [Mus musculus] 105844 4748 12.46333333 11.78666667 -0.080534196 Down 0.198258678 Card10 "caspase recruitment domain family, member 10" K07367|1|1e-128|464|lcm:102352360|caspase recruitment domain-containing protein 11 - - GO:0032147//activation of protein kinase activity;GO:0006915//apoptotic process gi|259089427|ref|NP_570929.2|/0/caspase recruitment domain-containing protein 10 [Mus musculus] 387609 4392 11.77666667 12.46 0.08137282 Up 0.198258678 Zhx2 zinc fingers and homeoboxes 2 - GO:0031981//nuclear lumen;GO:0016020//membrane GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0003677//DNA binding GO:0006401//RNA catabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0019827//stem cell population maintenance;GO:0030182//neuron differentiation "gi|148697335|gb|EDL29282.1|/0/zinc fingers and homeoboxes protein 2, isoform CRA_a, partial [Mus musculus]" 14559 1972 0.536666667 0.396666667 -0.436099115 Down 0.198249276 Gdf1 growth differentiation factor 1 K05495|1|2e-178|627|mmu:14559|growth differentiation factor 1/3 GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0005102//receptor binding;GO:0016410//N-acyltransferase activity;GO:0005102//receptor binding GO:0009888//tissue development;GO:0006796//phosphate-containing compound metabolic process;GO:0006672//ceramide metabolic process;GO:0007154//cell communication;GO:0007154//cell communication;GO:0009888//tissue development gi|20149718|ref|NP_619588.1|/0/ceramide synthase 1 [Mus musculus] 234094 5479.47 8.556666667 8.03 -0.091648902 Down 0.198239874 Arhgef10 Rho guanine nucleotide exchange factor (GEF) 10 K16727|1|0.0|2519|mmu:234094|Rho guanine nucleotide exchange factor 10 - - - gi|568953262|ref|XP_006508831.1|/0/PREDICTED: rho guanine nucleotide exchange factor 10 isoform X2 [Mus musculus] 16519 5232 8.8 8.266666667 -0.090197809 Down 0.198239874 Kcnj3 "potassium inwardly-rectifying channel, subfamily J, member 3" K04997|1|0.0|959|rno:50599|potassium inwardly-rectifying channel subfamily J member 3 GO:0009986//cell surface;GO:0042383//sarcolemma;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0042383//sarcolemma;GO:0005887//integral component of plasma membrane GO:0005488//binding;GO:0005242//inward rectifier potassium channel activity;GO:0005488//binding;GO:0005242//inward rectifier potassium channel activity GO:0007267//cell-cell signaling;GO:0009628//response to abiotic stimulus;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0007267//cell-cell signaling;GO:0009628//response to abiotic stimulus;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport "gi|528754483|gb|EPY74142.1|/4.88682e-122/potassium inwardly-rectifying channel, subfamily J, member 3 [Camelus ferus]" 11491 4450.62 8.893333333 8.363333333 -0.088646196 Down 0.198239874 Adam17 a disintegrin and metallopeptidase domain 17 K06059|1|0.0|1301|mmu:11491|disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86] GO:0005856//cytoskeleton;GO:0044459;GO:0016021//integral component of membrane;GO:0001726//ruffle;GO:0005924//cell-substrate adherens junction;GO:0005856//cytoskeleton;GO:0044459;GO:0016021//integral component of membrane;GO:0001726//ruffle;GO:0005924//cell-substrate adherens junction;GO:0005856//cytoskeleton;GO:0044459;GO:0016021//integral component of membrane;GO:0001726//ruffle;GO:0005924//cell-substrate adherens junction;GO:0005856//cytoskeleton;GO:0044459;GO:0016021//integral component of membrane;GO:0001726//ruffle;GO:0005924//cell-substrate adherens junction;GO:0005856//cytoskeleton;GO:0044459;GO:0016021//integral component of membrane;GO:0001726//ruffle;GO:0005924//cell-substrate adherens junction GO:0005126//cytokine receptor binding;GO:0004175//endopeptidase activity;GO:0019904//protein domain specific binding;GO:0046914//transition metal ion binding;GO:0005126//cytokine receptor binding;GO:0004175//endopeptidase activity;GO:0019904//protein domain specific binding;GO:0046914//transition metal ion binding;GO:0005126//cytokine receptor binding;GO:0004175//endopeptidase activity;GO:0019904//protein domain specific binding;GO:0046914//transition metal ion binding;GO:0005126//cytokine receptor binding;GO:0004175//endopeptidase activity;GO:0019904//protein domain specific binding;GO:0046914//transition metal ion binding;GO:0005126//cytokine receptor binding;GO:0004175//endopeptidase activity;GO:0019904//protein domain specific binding;GO:0046914//transition metal ion binding "GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006915//apoptotic process;GO:0031657//regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0016049//cell growth;GO:0055094//response to lipoprotein particle;GO:0006509//membrane protein ectodomain proteolysis;GO:0044319//wound healing, spreading of cells;GO:0030217//T cell differentiation;GO:0001819//positive regulation of cytokine production;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0002237//response to molecule of bacterial origin;GO:0008283//cell proliferation;GO:0007155//cell adhesion;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0001818//negative regulation of cytokine production;GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006915//apoptotic process;GO:0031657//regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0016049//cell growth;GO:0055094//response to lipoprotein particle;GO:0006509//membrane protein ectodomain proteolysis;GO:0044319//wound healing, spreading of cells;GO:0030217//T cell differentiation;GO:0001819//positive regulation of cytokine production;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0002237//response to molecule of bacterial origin;GO:0008283//cell proliferation;GO:0007155//cell adhesion;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0001818//negative regulation of cytokine production;GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006915//apoptotic process;GO:0031657//regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0016049//cell growth;GO:0055094//response to lipoprotein particle;GO:0006509//membrane protein ectodomain proteolysis;GO:0044319//wound healing, spreading of cells;GO:0030217//T cell differentiation;GO:0001819//positive regulation of cytokine production;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0002237//response to molecule of bacterial origin;GO:0008283//cell proliferation;GO:0007155//cell adhesion;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0001818//negative regulation of cytokine production;GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006915//apoptotic process;GO:0031657//regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0016049//cell growth;GO:0055094//response to lipoprotein particle;GO:0006509//membrane protein ectodomain proteolysis;GO:0044319//wound healing, spreading of cells;GO:0030217//T cell differentiation;GO:0001819//positive regulation of cytokine production;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0002237//response to molecule of bacterial origin;GO:0008283//cell proliferation;GO:0007155//cell adhesion;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0001818//negative regulation of cytokine production;GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006915//apoptotic process;GO:0031657//regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0016049//cell growth;GO:0055094//response to lipoprotein particle;GO:0006509//membrane protein ectodomain proteolysis;GO:0044319//wound healing, spreading of cells;GO:0030217//T cell differentiation;GO:0001819//positive regulation of cytokine production;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0002237//response to molecule of bacterial origin;GO:0008283//cell proliferation;GO:0007155//cell adhesion;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0001818//negative regulation of cytokine production;GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains" gi|471270257|ref|NP_001264195.1|/0/disintegrin and metalloproteinase domain-containing protein 17 isoform 2 precursor [Mus musculus] 76824 1997.75 101.2666667 105.21 0.055112467 Up 0.198174057 Mtfr1l mitochondrial fission regulator 1-like K13087|1|3e-09|66.2|gga:421691|bcl2 associated transcription factor 1 - - - "gi|148698058|gb|EDL30005.1|/4.27975e-137/RIKEN cDNA 2410166I05, isoform CRA_b, partial [Mus musculus]" 382913 1914 0.67 0.516666667 -0.374927286 Down 0.198127045 Neil2 nei like 2 (E. coli) K10568|1|0.0|666|mmu:382913|endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18] GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle "GO:0016835//carbon-oxygen lyase activity;GO:0046914//transition metal ion binding;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0003677//DNA binding;GO:0015631//tubulin binding" GO:0006281//DNA repair gi|118130803|ref|NP_963904.2|/0/endonuclease 8-like 2 [Mus musculus] 67384 4798 1.106666667 0.926666667 -0.256098359 Down 0.198080033 Bag4 BCL2-associated athanogene 4 K09558|1|2e-174|616|mmu:67384|BCL2-associated athanogene 4 GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0044444//cytoplasmic part - GO:0032233//positive regulation of actin filament bundle assembly;GO:0001934//positive regulation of protein phosphorylation;GO:0007155//cell adhesion;GO:0010761//fibroblast migration;GO:0007009//plasma membrane organization;GO:0030041//actin filament polymerization;GO:0006915//apoptotic process;GO:0051259//protein oligomerization;GO:0034612//response to tumor necrosis factor;GO:0030031//cell projection assembly;GO:0051253;GO:0010923//negative regulation of phosphatase activity;GO:0070849//response to epidermal growth factor "gi|23273683|gb|AAH37239.1|/8.1061e-175/Bag4 protein, partial [Mus musculus]" 72290 6453 1.116666667 0.933333333 -0.258734268 Down 0.198080033 Lsm11 U7 snRNP-specific Sm-like protein LSM11 - GO:0030532//small nuclear ribonucleoprotein complex;GO:0031981//nuclear lumen GO:0017069//snRNA binding GO:0006396//RNA processing;GO:0051320;GO:0008334//histone mRNA metabolic process;GO:0006366//transcription from RNA polymerase II promoter gi|29789219|ref|NP_082461.1|/4.30074e-118/U7 snRNA-associated Sm-like protein LSm11 [Mus musculus] 15510 2347 99.84333333 95.98333333 -0.056882184 Down 0.198023619 Hspd1 heat shock protein 1 (chaperonin) K04077|1|0.0|1060|rno:63868|chaperonin GroEL GO:0005783//endoplasmic reticulum;GO:0043234//protein complex;GO:0012505//endomembrane system;GO:0016021//integral component of membrane;GO:0030141//secretory granule;GO:0005743//mitochondrial inner membrane;GO:0005768//endosome;GO:0044421 GO:0008289//lipid binding;GO:0017046//peptide hormone binding;GO:0032550;GO:0046983//protein dimerization activity;GO:0019899//enzyme binding GO:0006954//inflammatory response;GO:0032481//positive regulation of type I interferon production;GO:0045190//isotype switching;GO:0000302//response to reactive oxygen species;GO:0002367//cytokine production involved in immune response;GO:0002237//response to molecule of bacterial origin;GO:0046683//response to organophosphorus;GO:0051084//'de novo' posttranslational protein folding;GO:0048545//response to steroid hormone;GO:0002224//toll-like receptor signaling pathway;GO:0002696//positive regulation of leukocyte activation;GO:0002424;GO:0035966//response to topologically incorrect protein;GO:0043066//negative regulation of apoptotic process;GO:0042110//T cell activation;GO:0009593//detection of chemical stimulus;GO:0031647//regulation of protein stability "gi|183396771|ref|NP_034607.3|/0/60 kDa heat shock protein, mitochondrial [Mus musculus]" 19240 565.67 100.9733333 97.12666667 -0.056034978 Down 0.198014216 Tmsb10 "thymosin, beta 10" K13785|1|8e-17|89.0|mdo:100019230|thymosin beta 10 GO:0043232;GO:0043232;GO:0043232 GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0030837//negative regulation of actin filament polymerization;GO:0007281//germ cell development;GO:0030837//negative regulation of actin filament polymerization;GO:0007281//germ cell development;GO:0030837//negative regulation of actin filament polymerization;GO:0007281//germ cell development gi|148692367|gb|EDL24314.1|/8.0127e-21/mCG7243 [Mus musculus] 59090 3667.36 92.99666667 89.15666667 -0.060836327 Down 0.197986009 Midn midnolin - GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - - gi|802083932|ref|NP_001292727.1|/0/midnolin isoform 2 [Mus musculus] 68917 636 86.58 90.39666667 0.062235774 Up 0.197976607 Hint2 histidine triad nucleotide binding protein 2 K15214|1|3e-47|190|tgu:100220398|TATA box-binding protein-associated factor RNA polymerase I subunit C;K02503|3|2e-44|180|hst:105181708|histidine triad (HIT) family protein GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity GO:0008202//steroid metabolic process;GO:0012501//programmed cell death "gi|110625719|ref|NP_081147.1|/6.94601e-68/histidine triad nucleotide-binding protein 2, mitochondrial precursor [Mus musculus]" 77417 795 0.13 0.24 0.884522783 Up 0.197976607 C030013C21Rik RIKEN cDNA C030013C21 gene - - - - - 100036768 2872 1.49 1.71 0.198683994 Up 0.197967204 Gm11696 predicted gene 11696 K04639|1|2e-19|100|pale:102891607|guanine nucleotide-binding protein subunit alpha-13 - - - gi|26389411|dbj|BAC25732.1|/1.52405e-53/unnamed protein product [Mus musculus] 74102 4200 1.5 1.72 0.197446064 Up 0.197967204 Slc35a5 "solute carrier family 35, member A5" "K15274|1|0.0|799|mmu:74102|solute carrier family 35 (probable UDP-sugar transporter), member A5" GO:0031224//intrinsic component of membrane GO:0015215//nucleotide transmembrane transporter activity;GO:0005402//cation:sugar symporter activity GO:0006862//nucleotide transport gi|568996413|ref|XP_006522710.1|/0/PREDICTED: probable UDP-sugar transporter protein SLC35A5 isoform X1 [Mus musculus] 17921 7196 1.68 1.46 -0.202492864 Down 0.197967204 Myo7a myosin VIIA K10359|1|0.0|4118|mmu:17921|myosin VII GO:0031513//nonmotile primary cilium;GO:0016461//unconventional myosin complex;GO:0005902//microvillus;GO:0005764//lysosome;GO:0048770;GO:0044459;GO:0031513//nonmotile primary cilium;GO:0015629//actin cytoskeleton;GO:0005902//microvillus;GO:0005764//lysosome;GO:0048770;GO:0044459;GO:0031513//nonmotile primary cilium;GO:0016461//unconventional myosin complex;GO:0005902//microvillus;GO:0005764//lysosome;GO:0048770;GO:0044459;GO:0031513//nonmotile primary cilium;GO:0016461//unconventional myosin complex;GO:0005902//microvillus;GO:0005764//lysosome;GO:0048770;GO:0044459 "GO:0032550;GO:0003779//actin binding;GO:0042802//identical protein binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003779//actin binding;GO:0003774//motor activity;GO:0032550;GO:0003779//actin binding;GO:0042802//identical protein binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003779//actin binding;GO:0042802//identical protein binding;GO:0042623//ATPase activity, coupled" GO:0006909//phagocytosis;GO:0006928//movement of cell or subcellular component;GO:0007033//vacuole organization;GO:0050953//sensory perception of light stimulus;GO:0015031//protein transport;GO:0050954//sensory perception of mechanical stimulus;GO:0002093//auditory receptor cell morphogenesis;GO:0033059//cellular pigmentation;GO:0006909//phagocytosis;GO:0006928//movement of cell or subcellular component;GO:0007033//vacuole organization;GO:0050953//sensory perception of light stimulus;GO:0015031//protein transport;GO:0050954//sensory perception of mechanical stimulus;GO:0002093//auditory receptor cell morphogenesis;GO:0001754//eye photoreceptor cell differentiation;GO:0006909//phagocytosis;GO:0006928//movement of cell or subcellular component;GO:0007033//vacuole organization;GO:0050953//sensory perception of light stimulus;GO:0015031//protein transport;GO:0050954//sensory perception of mechanical stimulus;GO:0002093//auditory receptor cell morphogenesis;GO:0033059//cellular pigmentation;GO:0006909//phagocytosis;GO:0006928//movement of cell or subcellular component;GO:0007033//vacuole organization;GO:0050953//sensory perception of light stimulus;GO:0015031//protein transport;GO:0050954//sensory perception of mechanical stimulus;GO:0002093//auditory receptor cell morphogenesis;GO:0033059//cellular pigmentation gi|115511010|ref|NP_032689.2|/0/unconventional myosin-VIIa isoform 2 [Mus musculus] 12815 6346 0.41 0.283333333 -0.533123569 Down 0.197957802 Col11a2 "collagen, type XI, alpha 2" "K19721|1|0.0|1165|rno:294279|collagen, type V/XI/XXIV/XXVII, alpha" - - - - 237211 2984 0.41 0.283333333 -0.533123569 Down 0.197957802 Fancb "Fanconi anemia, complementation group B" K10889|1|0.0|1424|mmu:237211|fanconi anemia group B protein - - - - 433273 1245 0.136666667 0.25 0.871266686 Up 0.197873181 Gm5523 glyceraldehyde-3-phosphate dehydrogenase pseudogene K00134|1|2e-158|482|mmu:14433|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0015631//tubulin binding" GO:0007010//cytoskeleton organization;GO:0070997//neuron death;GO:0031647//regulation of protein stability;GO:0012501//programmed cell death;GO:0006412//translation;GO:0006007//glucose catabolic process;GO:0018119//peptidyl-cysteine S-nitrosylation;GO:0044710;GO:1901698//response to nitrogen compound;GO:0034341//response to interferon-gamma;GO:0032502//developmental process gi|576080555|ref|NP_001276655.1|/7.0328e-161/glyceraldehyde-3-phosphate dehydrogenase isoform 1 [Mus musculus] 69276 3966 12.31333333 12.98 0.076069018 Up 0.197807364 Sec62 SEC62 homolog (S. cerevisiae) K12275|1|2e-84|317|mmu:69276|translocation protein SEC62 GO:0005856//cytoskeleton;GO:0016234//inclusion body;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0022892//substrate-specific transporter activity GO:0045184//establishment of protein localization gi|39930429|ref|NP_081292.1|/1.55444e-83/translocation protein SEC62 [Mus musculus] 234396 2712 0.213333333 0.336666667 0.658211483 Up 0.197769754 Ankle1 ankyrin repeat and LEM domain containing 1 K01077|1|7e-72|275|xma:102235213|alkaline phosphatase [EC:3.1.3.1];K10380|2|1e-08|64.7|bmor:101740231|ankyrin;K18441|3|2e-08|64.3|aqu:100641148|cytohesin - - - gi|189181677|ref|NP_766344.2|/0/ankyrin repeat and LEM domain-containing protein 1 isoform 1 [Mus musculus] 52187 5047 23.81 22.75333333 -0.065489707 Down 0.197741547 Rragd Ras-related GTP binding D K16186|1|0.0|769|rno:297960|Ras-related GTP-binding protein C/D GO:0000323//lytic vacuole GO:0046983//protein dimerization activity;GO:0032550 - gi|120444910|ref|NP_081767.2|/0/ras-related GTP-binding protein D [Mus musculus] 109006 4327 21.90666667 20.84666667 -0.071553261 Down 0.197741547 Ciapin1 cytokine induced apoptosis inhibitor 1 - GO:0031981//nuclear lumen - GO:0048534//hematopoietic or lymphoid organ development;GO:0006915//apoptotic process gi|19527376|ref|NP_598902.1|/1.16096e-164/anamorsin [Mus musculus] 246228 3140 5.683333333 6.11 0.104435047 Up 0.197666328 Vwa1 von Willebrand factor A domain containing 1 "K08132|1|3e-40|170|cmk:103187020|collagen, type XII, alpha" GO:0005578//proteinaceous extracellular matrix GO:0005515//protein binding GO:0043062//extracellular structure organization;GO:0044708//single-organism behavior gi|240255600|ref|NP_680085.3|/0/von Willebrand factor A domain-containing protein 1 precursor [Mus musculus] 270201 4573 6.04 6.473333333 0.099960245 Up 0.197666328 Klhl18 kelch-like 18 K10455|1|0.0|1199|pps:100991845|kelch-like protein 18 - - - gi|50510643|dbj|BAD32307.1|/0/mKIAA0795 protein [Mus musculus] 101351 3205 6.476666667 6.05 -0.098316353 Down 0.197666328 Eogt EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase K18134|1|0.0|1113|mmu:101351|protein O-GlcNAc transferase [EC:2.4.1.255] GO:0043231//intracellular membrane-bounded organelle GO:0008375//acetylglucosaminyltransferase activity GO:0006486//protein glycosylation "gi|148666934|gb|EDK99350.1|/0/RIKEN cDNA A130022J15, isoform CRA_b, partial [Mus musculus]" 56426 1923 6.64 6.21 -0.096589973 Down 0.197666328 Pdcd10 programmed cell death 10 K18269|1|9e-113|410|acs:100552514|programmed cell death protein 10 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system;GO:0016020//membrane GO:0042802//identical protein binding GO:0048646//anatomical structure formation involved in morphogenesis;GO:0006915//apoptotic process;GO:0008283//cell proliferation;GO:0043405//regulation of MAP kinase activity gi|31560391|ref|NP_062719.2|/7.54377e-112/programmed cell death protein 10 [Mus musculus] 56784 8277.25 6.7 6.27 -0.095695653 Down 0.197666328 Ralgapa1 "Ral GTPase activating protein, alpha subunit 1" K17700|1|6e-19|100|mde:101896864|RAP1 GTPase activating protein 1;K07207|2|3e-18|98.6|bfo:BRAFLDRAFT_64809|tuberous sclerosis 2 - - - gi|51230429|ref|NP_064378.4|/0/ral GTPase-activating protein subunit alpha-1 isoform 2 [Mus musculus] 22201 4073.53 83.82333333 87.44333333 0.060996504 Up 0.197647523 Uba1 ubiquitin-like modifier activating enzyme 1 K03178|1|0.0|2082|mmu:22201|ubiquitin-activating enzyme E1 [EC:6.2.1.45] - - - - 85305 2079.04 80.40666667 84.02 0.063417663 Up 0.197619316 Kars lysyl-tRNA synthetase "K04567|1|0.0|1094|mmu:85305|lysyl-tRNA synthetase, class II [EC:6.1.1.6]" GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0043169//cation binding;GO:0032550;GO:0031406//carboxylic acid binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0043169//cation binding;GO:0032550;GO:0031406//carboxylic acid binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0043169//cation binding;GO:0032550;GO:0031406//carboxylic acid binding;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation;GO:0015960;GO:0006418//tRNA aminoacylation for protein translation;GO:0015960;GO:0006418//tRNA aminoacylation for protein translation;GO:0015960 "gi|148679579|gb|EDL11526.1|/0/mCG141545, isoform CRA_c, partial [Mus musculus]" 57916 750 0.203333333 0.32 0.654225163 Up 0.197581707 Tnfrsf13b "tumor necrosis factor receptor superfamily, member 13b" K05150|1|5e-150|531|mmu:57916|tumor necrosis factor receptor superfamily member 13B GO:0009986//cell surface;GO:0016021//integral component of membrane - GO:0030888//regulation of B cell proliferation gi|10946668|ref|NP_067324.1|/4.03915e-149/tumor necrosis factor receptor superfamily member 13B [Mus musculus] 56445 2839 87.32 90.89666667 0.057915259 Up 0.197468878 Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 K09503|1|0.0|728|cfa:478143|DnaJ homolog subfamily A member 2 - - - - 66385 3653 7.803333333 8.323333333 0.093070887 Up 0.197450073 Ppp1r7 "protein phosphatase 1, regulatory (inhibitor) subunit 7" K17550|1|7e-178|627|mmu:66385|protein phosphatase 1 regulatory subunit 7 GO:0043231//intracellular membrane-bounded organelle GO:0019888//protein phosphatase regulator activity GO:0019222//regulation of metabolic process gi|12963569|ref|NP_075689.1|/6.41992e-177/protein phosphatase 1 regulatory subunit 7 [Mus musculus] 74132 3269.56 7.963333333 8.48 0.090691817 Up 0.197450073 Rnf6 ring finger protein (C3H2C3 type) 6 K16271|1|2e-109|400|cmk:103178812|E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27] GO:0043005//neuron projection;GO:0016604//nuclear body;GO:0043005//neuron projection;GO:0016604//nuclear body;GO:0043005//neuron projection;GO:0016604//nuclear body;GO:0043005//neuron projection;GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0035258//steroid hormone receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0035258//steroid hormone receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0035258//steroid hormone receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0035258//steroid hormone receptor binding;GO:0019787//ubiquitin-like protein transferase activity "GO:0000209//protein polyubiquitination;GO:0006351//transcription, DNA-templated;GO:0030521//androgen receptor signaling pathway;GO:0030308//negative regulation of cell growth;GO:0019941//modification-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0006351//transcription, DNA-templated;GO:0030521//androgen receptor signaling pathway;GO:0030308//negative regulation of cell growth;GO:0019941//modification-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0006351//transcription, DNA-templated;GO:0030521//androgen receptor signaling pathway;GO:0030308//negative regulation of cell growth;GO:0019941//modification-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0006351//transcription, DNA-templated;GO:0030521//androgen receptor signaling pathway;GO:0030308//negative regulation of cell growth;GO:0019941//modification-dependent protein catabolic process" gi|367460082|ref|NP_001243015.1|/0/E3 ubiquitin-protein ligase RNF6 isoform 2 [Mus musculus] 223920 2126 0.696666667 0.543333333 -0.358630978 Down 0.19731844 Soat2 sterol O-acyltransferase 2 K00637|1|0.0|940|mmu:223920|sterol O-acyltransferase [EC:2.3.1.26] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0031090//organelle membrane GO:0032934//sterol binding;GO:0043168//anion binding;GO:0004772//sterol O-acyltransferase activity GO:0031667//response to nutrient levels;GO:0034434//sterol esterification;GO:0030301//cholesterol transport;GO:0016125//sterol metabolic process;GO:0034377//plasma lipoprotein particle assembly gi|22122547|ref|NP_666176.1|/0/sterol O-acyltransferase 2 [Mus musculus] 70675 9749 1.22 1.033333333 -0.239575433 Down 0.19731844 Vcpip1 valosin containing protein (p97)/p47 complex interacting protein 1 K11861|1|0.0|2294|mmu:70675|deubiquitinating protein VCIP135 [EC:3.4.19.12] GO:0044431//Golgi apparatus part "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0007030//Golgi organization;GO:0048284//organelle fusion;GO:0032446//protein modification by small protein conjugation;GO:0000087//mitotic M phase gi|28972858|dbj|BAC65845.1|/0/mKIAA1850 protein [Mus musculus] 218756 7389 1.206666667 1.02 -0.242458044 Down 0.19731844 Slc4a7 "solute carrier family 4, sodium bicarbonate cotransporter, member 7" "K13858|1|0.0|2095|mmu:218756|solute carrier family 4 (sodium bicarbonate cotransporter), member 7" GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031982//vesicle;GO:0044424 GO:0015301//anion:anion antiporter activity GO:0021548//pons development;GO:0050953//sensory perception of light stimulus;GO:0042491//auditory receptor cell differentiation;GO:0010623//programmed cell death involved in cell development;GO:0001754//eye photoreceptor cell differentiation;GO:0030001//metal ion transport gi|117320529|ref|NP_001028442.2|/0/sodium bicarbonate cotransporter 3 [Mus musculus] 13383 4730.63 12.8 12.14333333 -0.075979316 Down 0.197290233 Dlg1 "discs, large homolog 1 (Drosophila)" K12076|1|0.0|988|mmu:13383|disks large protein 1 GO:0043296//apical junction complex;GO:0033267;GO:0043234//protein complex;GO:0016323//basolateral plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044327//dendritic spine head;GO:0042383//sarcolemma;GO:0043209//myelin sheath;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0097060//synaptic membrane;GO:0043296//apical junction complex;GO:0033267;GO:0043234//protein complex;GO:0016323//basolateral plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044327//dendritic spine head;GO:0042383//sarcolemma;GO:0043209//myelin sheath;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0097060//synaptic membrane;GO:0043296//apical junction complex;GO:0033267;GO:0043234//protein complex;GO:0016323//basolateral plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044327//dendritic spine head;GO:0042383//sarcolemma;GO:0043209//myelin sheath;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0097060//synaptic membrane;GO:0043296//apical junction complex;GO:0033267;GO:0043234//protein complex;GO:0016323//basolateral plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044327//dendritic spine head;GO:0042383//sarcolemma;GO:0043209//myelin sheath;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0097060//synaptic membrane;GO:0043296//apical junction complex;GO:0033267;GO:0043234//protein complex;GO:0016323//basolateral plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044327//dendritic spine head;GO:0042383//sarcolemma;GO:0043209//myelin sheath;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0097060//synaptic membrane GO:0019904//protein domain specific binding;GO:0035254//glutamate receptor binding;GO:0019901//protein kinase binding;GO:0016247//channel regulator activity;GO:0019904//protein domain specific binding;GO:0035254//glutamate receptor binding;GO:0019901//protein kinase binding;GO:0016247//channel regulator activity;GO:0019904//protein domain specific binding;GO:0035254//glutamate receptor binding;GO:0019901//protein kinase binding;GO:0016247//channel regulator activity;GO:0019904//protein domain specific binding;GO:0035254//glutamate receptor binding;GO:0019901//protein kinase binding;GO:0016247//channel regulator activity;GO:0019904//protein domain specific binding;GO:0035254//glutamate receptor binding;GO:0019901//protein kinase binding;GO:0016247//channel regulator activity GO:0048562//embryonic organ morphogenesis;GO:0050673//epithelial cell proliferation;GO:0003006//developmental process involved in reproduction;GO:0048754//branching morphogenesis of an epithelial tube;GO:0007009//plasma membrane organization;GO:0008104//protein localization;GO:0035264//multicellular organism growth;GO:0014821;GO:0045927//positive regulation of growth;GO:0060537//muscle tissue development;GO:0006873//cellular ion homeostasis;GO:0000278//mitotic cell cycle;GO:0002367//cytokine production involved in immune response;GO:0043010//camera-type eye development;GO:0008285//negative regulation of cell proliferation;GO:0006813//potassium ion transport;GO:0007155//cell adhesion;GO:0007043//cell-cell junction assembly;GO:0030041//actin filament polymerization;GO:0042098//T cell proliferation;GO:0045860//positive regulation of protein kinase activity;GO:0051130//positive regulation of cellular component organization;GO:0009988//cell-cell recognition;GO:0048562//embryonic organ morphogenesis;GO:0050673//epithelial cell proliferation;GO:0003006//developmental process involved in reproduction;GO:0048754//branching morphogenesis of an epithelial tube;GO:0007009//plasma membrane organization;GO:0008104//protein localization;GO:0035264//multicellular organism growth;GO:0014821;GO:0045927//positive regulation of growth;GO:0060537//muscle tissue development;GO:0006873//cellular ion homeostasis;GO:0000278//mitotic cell cycle;GO:0002367//cytokine production involved in immune response;GO:0043010//camera-type eye development;GO:0008285//negative regulation of cell proliferation;GO:0006813//potassium ion transport;GO:0007155//cell adhesion;GO:0007043//cell-cell junction assembly;GO:0030041//actin filament polymerization;GO:0042098//T cell proliferation;GO:0045860//positive regulation of protein kinase activity;GO:0051130//positive regulation of cellular component organization;GO:0009988//cell-cell recognition;GO:0048562//embryonic organ morphogenesis;GO:0050673//epithelial cell proliferation;GO:0003006//developmental process involved in reproduction;GO:0048754//branching morphogenesis of an epithelial tube;GO:0007009//plasma membrane organization;GO:0008104//protein localization;GO:0035264//multicellular organism growth;GO:0014821;GO:0045927//positive regulation of growth;GO:0060537//muscle tissue development;GO:0006873//cellular ion homeostasis;GO:0000278//mitotic cell cycle;GO:0002367//cytokine production involved in immune response;GO:0043010//camera-type eye development;GO:0008285//negative regulation of cell proliferation;GO:0006813//potassium ion transport;GO:0007155//cell adhesion;GO:0007043//cell-cell junction assembly;GO:0030041//actin filament polymerization;GO:0042098//T cell proliferation;GO:0045860//positive regulation of protein kinase activity;GO:0051130//positive regulation of cellular component organization;GO:0009988//cell-cell recognition;GO:0048562//embryonic organ morphogenesis;GO:0050673//epithelial cell proliferation;GO:0003006//developmental process involved in reproduction;GO:0048754//branching morphogenesis of an epithelial tube;GO:0007009//plasma membrane organization;GO:0008104//protein localization;GO:0035264//multicellular organism growth;GO:0014821;GO:0045927//positive regulation of growth;GO:0060537//muscle tissue development;GO:0006873//cellular ion homeostasis;GO:0000278//mitotic cell cycle;GO:0002367//cytokine production involved in immune response;GO:0043010//camera-type eye development;GO:0008285//negative regulation of cell proliferation;GO:0006813//potassium ion transport;GO:0007155//cell adhesion;GO:0007043//cell-cell junction assembly;GO:0030041//actin filament polymerization;GO:0042098//T cell proliferation;GO:0045860//positive regulation of protein kinase activity;GO:0051130//positive regulation of cellular component organization;GO:0009988//cell-cell recognition;GO:0048562//embryonic organ morphogenesis;GO:0050673//epithelial cell proliferation;GO:0003006//developmental process involved in reproduction;GO:0048754//branching morphogenesis of an epithelial tube;GO:0007009//plasma membrane organization;GO:0008104//protein localization;GO:0035264//multicellular organism growth;GO:0014821;GO:0045927//positive regulation of growth;GO:0060537//muscle tissue development;GO:0006873//cellular ion homeostasis;GO:0000278//mitotic cell cycle;GO:0002367//cytokine production involved in immune response;GO:0043010//camera-type eye development;GO:0008285//negative regulation of cell proliferation;GO:0006813//potassium ion transport;GO:0007155//cell adhesion;GO:0007043//cell-cell junction assembly;GO:0030041//actin filament polymerization;GO:0042098//T cell proliferation;GO:0045860//positive regulation of protein kinase activity;GO:0051130//positive regulation of cellular component organization;GO:0009988//cell-cell recognition gi|356995923|ref|NP_001239365.1|/0/disks large homolog 1 isoform 5 [Mus musculus] 224273 6544 12.8 12.13666667 -0.07677157 Down 0.197290233 Crybg3 beta-gamma crystallin domain containing 3 K16810|1|1e-09|69.3|bacu:103015945|TBCC domain-containing protein 1;K01886|3|1e-07|62.8|asn:102367728|glutaminyl-tRNA synthetase [EC:6.1.1.18] - - - gi|568995261|ref|XP_006522158.1|/0/PREDICTED: beta/gamma crystallin domain-containing protein 3 isoform X1 [Mus musculus] 214951 1557 3.136666667 2.846666667 -0.139958653 Down 0.197243221 Rhbdl1 "rhomboid, veinlet-like 1 (Drosophila)" K02857|1|0.0|730|mmu:214951|rhomboid-related protein 1/2/3 [EC:3.4.21.105] GO:0031224//intrinsic component of membrane "GO:0046872//metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process "gi|148690517|gb|EDL22464.1|/0/rhomboid, veinlet-like 1 (Drosophila), isoform CRA_b, partial [Mus musculus]" 208659 2614 2.86 3.15 0.139336682 Up 0.197243221 Fam20a "family with sequence similarity 20, member A" K19347|1|2e-92|343|ccw:104696523|SUN domain-containing protein 1/2;K00327|2|5e-62|242|tsp:Tsp_02446|NADPH-ferrihemoprotein reductase [EC:1.6.2.4] - - GO:0034505//tooth mineralization gi|24418883|ref|NP_722477.1|/0/pseudokinase FAM20A precursor [Mus musculus] 11855 5197 3.026666667 2.74 -0.143553904 Down 0.197243221 Arhgap5 Rho GTPase activating protein 5 K13709|1|0.0|2898|mmu:11855|Rho GTPase-activating protein 5 GO:0044424 GO:0032550;GO:0008047//enzyme activator activity;GO:0019904//protein domain specific binding GO:0016477//cell migration;GO:0035556//intracellular signal transduction;GO:0032535//regulation of cellular component size;GO:0048732//gland development gi|86262151|ref|NP_033836.2|/0/rho GTPase-activating protein 5 [Mus musculus] 71275 1412 0.14 0.253333333 0.855610091 Up 0.197139795 Noxred1 NADP+ dependent oxidoreductase domain containing 1 K00286|1|6e-07|58.2|phi:102100161|pyrroline-5-carboxylate reductase [EC:1.5.1.2] - "GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor" GO:0006560//proline metabolic process gi|116812877|ref|NP_082020.1|/0/NADP-dependent oxidoreductase domain-containing protein 1 [Mus musculus] 13016 2431.18 77.33 80.69333333 0.061421274 Up 0.19712099 Ctbp1 C-terminal binding protein 1 K04496|1|0.0|783|cge:100766703|C-terminal binding protein GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0000166//nucleotide binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0016740//transferase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0042802//identical protein binding;GO:0008134//transcription factor binding;GO:0000166//nucleotide binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0016740//transferase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0042802//identical protein binding;GO:0008134//transcription factor binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0016575//histone deacetylation;GO:0045444//fat cell differentiation;GO:0044710;GO:0035067//negative regulation of histone acetylation;GO:0007049//cell cycle;GO:0006366//transcription from RNA polymerase II promoter;GO:0016575//histone deacetylation;GO:0008283//cell proliferation;GO:0045444//fat cell differentiation;GO:0044710;GO:0035067//negative regulation of histone acetylation;GO:0019058//viral life cycle;GO:0007049//cell cycle gi|311893326|ref|NP_001185789.1|/0/C-terminal-binding protein 1 isoform 2 [Mus musculus] 70873 1877.23 77.74333333 74.40666667 -0.063287077 Down 0.197102185 Cnbd2 cyclic nucleotide binding domain containing 2 K08014|1|2e-08|63.5|ola:101158525|Rap guanine nucleotide exchange factor 3;K07376|2|4e-08|62.4|tsp:Tsp_02535|cGMP-dependent protein kinase 1 [EC:2.7.11.12];K19477|4|8e-08|61.6|ola:101165996|cGMP-dependent protein kinase 2 [EC:2.7.11.12] - - - gi|166795271|ref|NP_081861.2|/0/cyclic nucleotide-binding domain-containing protein 2 isoform 1 [Mus musculus] 237082 2492 2.48 2.753333333 0.15083916 Up 0.197026966 Nxt2 nuclear transport factor 2-like export factor 2 K14285|1|2e-77|293|mmu:237082|NTF2-related export protein 1/2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0045184//establishment of protein localization;GO:0050658//RNA transport;GO:0045184//establishment of protein localization;GO:0050658//RNA transport;GO:0045184//establishment of protein localization;GO:0050658//RNA transport;GO:0045184//establishment of protein localization;GO:0050658//RNA transport gi|594542509|ref|NP_001277461.1|/1.29527e-90/NTF2-related export protein 2 isoform b [Mus musculus] 231807 2557 2.556666667 2.83 0.146537976 Up 0.197026966 BC037034 cDNA sequence BC037034 K09677|1|1e-48|197|ggo:101128727|galactose-3-O-sulfotransferase 4 [EC:2.8.2.-];K00993|4|1e-17|94.7|acs:100560665|ethanolaminephosphotransferase [EC:2.7.8.1] - - - gi|264681507|ref|NP_694801.2|/0/uncharacterized protein C7orf43 homolog [Mus musculus] 223435 11521 2.673333333 2.406666667 -0.1516034 Down 0.197026966 Trio triple functional domain (PTPRF interacting) K08810|1|0.0|5591|mmu:223435|triple functional domain protein [EC:2.7.11.1] - - - gi|145587082|ref|NP_001074771.1|/0/triple functional domain protein [Mus musculus] 217588 1509 2.73 2.463333333 -0.148289087 Down 0.197026966 Mbip MAP3K12 binding inhibitory protein 1 K03635|1|2e-30|135|ame:414033|molybdopterin synthase catalytic subunit [EC:2.8.1.12] GO:0000123//histone acetyltransferase complex GO:0005515//protein binding GO:0016573//histone acetylation gi|21703882|ref|NP_663417.1|/1.68661e-169/MAP3K12-binding inhibitory protein 1 [Mus musculus] 73844 3723 0.45 0.316666667 -0.506959989 Down 0.196989357 Ankrd45 ankyrin repeat domain 45 "K14726|1|1e-91|341|ssc:100624136|solute carrier family 9 (sodium/hydrogen exchanger), member 10/11;K16823|3|7e-08|62.8|dre:407983|apoptosis-stimulating of p53 protein 2" - - - gi|254675129|ref|NP_082940.1|/6.0293e-122/ankyrin repeat domain-containing protein 45 [Mus musculus] 233545 4031 5.023333333 4.646666667 -0.112448856 Down 0.196942345 Emsy "EMSY, BRCA2-interacting transcriptional repressor" K14972|1|5e-08|63.5|hro:HELRODRAFT_193805|PAX-interacting protein 1;K07197|2|2e-07|61.2|crg:105345607|sterol regulatory element-binding transcription factor 1;K15157|3|3e-06|57.4|gfr:102044991|mediator of RNA polymerase II transcription subunit 15;K11320|4|6e-06|56.6|mcf:102142983|E1A-binding protein p400 [EC:3.6.4.-];K11321|5|1e-05|55.8|obi:106876373|bromodomain-containing protein 8 - - "GO:0006259//DNA metabolic process;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization;GO:0033554//cellular response to stress" gi|124249084|ref|NP_758484.2|/0/BRCA2-interacting transcriptional repressor EMSY [Mus musculus] 71735 2201 4.78 5.16 0.110360447 Up 0.196942345 Lrwd1 leucine-rich repeats and WD repeat domain containing 1 K13131|1|5e-49|198|smm:Smp_171170|ATP-dependent RNA helicase DDX20 [EC:3.6.4.13] "GO:0043231//intracellular membrane-bounded organelle;GO:0000808//origin recognition complex;GO:0000781//chromosome, telomeric region;GO:0000775//chromosome, centromeric region" GO:0042393//histone binding;GO:0000166//nucleotide binding GO:0006259//DNA metabolic process;GO:0070199//establishment of protein localization to chromosome;GO:0006325//chromatin organization "gi|148687374|gb|EDL19321.1|/0/RIKEN cDNA 1200011O22, isoform CRA_a, partial [Mus musculus]" 170707 5766 5.006666667 4.623333333 -0.114917025 Down 0.196942345 Usp48 ubiquitin specific peptidase 48 K11858|1|0.0|2120|mmu:170707|ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12] GO:0097060//synaptic membrane;GO:0044425;GO:0031981//nuclear lumen "GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019941//modification-dependent protein catabolic process gi|755509333|ref|XP_011248503.1|/0/PREDICTED: ubiquitin carboxyl-terminal hydrolase 48 isoform X4 [Mus musculus] 11747 1738 72.84333333 76.10333333 0.063162703 Up 0.196932942 Anxa5 annexin A5 K16646|1|3e-170|600|mmu:11747|annexin A5 GO:0031988//membrane-bounded vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0009986//cell surface;GO:0031674//I band;GO:0044291//cell-cell contact zone;GO:0072562//blood microparticle;GO:0005886//plasma membrane GO:0042277//peptide binding;GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0005102//receptor binding GO:0010038//response to metal ion;GO:0051259//protein oligomerization;GO:0006915//apoptotic process;GO:2000145//regulation of cell motility;GO:0007596//blood coagulation gi|6753060|ref|NP_033803.1|/2.6524e-169/annexin A5 [Mus musculus] 11732 3511 80.69 83.96333333 0.057369553 Up 0.196932942 Ank progressive ankylosis - GO:0016021//integral component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity GO:0048731//system development;GO:0044708//single-organism behavior;GO:0030278//regulation of ossification;GO:0006817//phosphate ion transport gi|795412631|ref|XP_011757635.1|/0/PREDICTED: progressive ankylosis protein homolog [Macaca nemestrina] 22027 2759 73.54 76.81333333 0.062827581 Up 0.196932942 Hsp90b1 "heat shock protein 90, beta (Grp94), member 1" K09487|1|0.0|1283|mmu:22027|heat shock protein 90kDa beta GO:0044432;GO:0048770;GO:0031090//organelle membrane;GO:0005886//plasma membrane GO:0032550;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0070325//lipoprotein particle receptor binding;GO:0019902//phosphatase binding GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006874//cellular calcium ion homeostasis;GO:0033198//response to ATP;GO:0010921//regulation of phosphatase activity;GO:0006915//apoptotic process;GO:0007015//actin filament organization;GO:0045184//establishment of protein localization;GO:0006952//defense response;GO:0030968//endoplasmic reticulum unfolded protein response "gi|14714615|gb|AAH10445.1|/0/Heat shock protein 90, beta (Grp94), member 1 [Mus musculus]" 71675 4140 1.366666667 1.58 0.209263149 Up 0.196895333 0610010F05Rik RIKEN cDNA 0610010F05 gene - - - - gi|37360572|dbj|BAC98264.1|/0/mKIAA1841 protein [Mus musculus] 19682 1261 1.333333333 1.543333333 0.211012193 Up 0.196895333 Rdh5 retinol dehydrogenase 5 K00061|1|2e-171|603|mmu:19682|11-cis-retinol dehydrogenase [EC:1.1.1.315] GO:0044432 GO:0036094//small molecule binding;GO:0003824//catalytic activity GO:0050953//sensory perception of light stimulus;GO:0044710 "gi|148692686|gb|EDL24633.1|/1.34877e-174/retinol dehydrogenase 5, isoform CRA_b, partial [Mus musculus]" 76246 4680 12.05666667 12.70333333 0.07537601 Up 0.19688593 Rtf1 "RTF1, Paf1/RNA polymerase II complex component" K15178|1|0.0|1012|mmu:76246|RNA polymerase-associated protein RTF1 GO:0008023//transcription elongation factor complex GO:0043566//structure-specific DNA binding GO:0031062//positive regulation of histone methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0035987//endodermal cell differentiation;GO:0006368//transcription elongation from RNA polymerase II promoter gi|195976788|ref|NP_084388.2|/0/RNA polymerase-associated protein RTF1 homolog precursor [Mus musculus] 103236 2299.56 70.43666667 73.67 0.064750606 Up 0.196876528 Csnk1g2 "casein kinase 1, gamma 2" "K08958|1|0.0|758|mmu:103236|casein kinase 1, gamma [EC:2.7.11.1]" GO:0044424;GO:0044424 GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0033218//amide binding;GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0033218//amide binding GO:0006468//protein phosphorylation;GO:0007166//cell surface receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0007166//cell surface receptor signaling pathway gi|227430313|ref|NP_001153063.1|/0/casein kinase I isoform gamma-2 isoform 2 [Mus musculus] 15205 1487 22.37666667 21.36 -0.067083495 Down 0.196857723 Hes1 hairy and enhancer of split 1 (Drosophila) K06054|1|5e-108|394|mmu:15205|hairy and enhancer of split 1 GO:0031981//nuclear lumen "GO:0044212//transcription regulatory region DNA binding;GO:0042802//identical protein binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0019899//enzyme binding" "GO:0021700//developmental maturation;GO:0045632;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0009794//regulation of mitotic cell cycle, embryonic;GO:0021879//forebrain neuron differentiation;GO:0045687//positive regulation of glial cell differentiation;GO:0048870//cell motility;GO:0072028//nephron morphogenesis;GO:0045686//negative regulation of glial cell differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0055001//muscle cell development;GO:0021545//cranial nerve development;GO:0030509//BMP signaling pathway;GO:0003151//outflow tract morphogenesis;GO:0045444//fat cell differentiation;GO:0007219//Notch signaling pathway;GO:0022610;GO:0035904//aorta development;GO:0003281//ventricular septum development;GO:0006606//protein import into nucleus;GO:0021983//pituitary gland development;GO:0002328//pro-B cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0003310//pancreatic A cell differentiation;GO:0009912//auditory receptor cell fate commitment;GO:0048514//blood vessel morphogenesis;GO:0040034//regulation of development, heterochronic;GO:0051099//positive regulation of binding;GO:0065003;GO:0030323//respiratory tube development;GO:0042098//T cell proliferation;GO:0003264//regulation of cardioblast proliferation;GO:0019827//stem cell population maintenance;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0030917//midbrain-hindbrain boundary development;GO:0048568//embryonic organ development;GO:0060562//epithelial tube morphogenesis" gi|6680205|ref|NP_032261.1|/4.00918e-107/transcription factor HES-1 [Mus musculus] 68045 1510 71.3 74.48666667 0.063080125 Up 0.196763699 2700060E02Rik RIKEN cDNA 2700060E02 gene K15433|1|3e-129|464|mmu:68045|RLL motif containing protein 1 GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043232 GO:0001099//basal RNA polymerase II transcription machinery binding GO:0006366//transcription from RNA polymerase II promoter gi|13386026|ref|NP_080804.1|/2.47079e-128/UPF0568 protein C14orf166 homolog [Mus musculus] 17916 3833 1.196666667 1.396666667 0.2229664 Up 0.196716687 Myo1f myosin IF K10356|1|0.0|2111|mmu:17916|myosin I GO:0016459//myosin complex;GO:0005884//actin filament GO:0008092//cytoskeletal protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0016477//cell migration;GO:0002444;GO:0042742//defense response to bacterium;GO:0002283//neutrophil activation involved in immune response;GO:0030036//actin cytoskeleton organization;GO:0007155//cell adhesion;GO:0031347//regulation of defense response gi|255069756|ref|NP_444444.2|/0/unconventional myosin-If [Mus musculus] 56195 3362.19 3.41 3.723333333 0.126823041 Up 0.19668848 Ptbp2 polypyrimidine tract binding protein 2 K14948|1|0.0|960|gga:424479|polypyrimidine tract-binding protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0003723//RNA binding;GO:0036094//small molecule binding GO:0000245//spliceosomal complex assembly;GO:0042127//regulation of cell proliferation gi|971408095|ref|XP_015146220.1|/0/PREDICTED: polypyrimidine tract-binding protein 2 isoform X4 [Gallus gallus] 235527 3259 3.65 3.343333333 -0.126609264 Down 0.19668848 Plscr4 phospholipid scramblase 4 - GO:0031224//intrinsic component of membrane GO:0005102//receptor binding GO:0032496//response to lipopolysaccharide gi|30520123|ref|NP_848826.1|/2.14983e-168/phospholipid scramblase 4 [Mus musculus] 71375 2611 3.436666667 3.13 -0.13484727 Down 0.19668848 Foxn3 forkhead box N3 K09407|1|0.0|800|mmu:71375|forkhead box protein N GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding "GO:0044763;GO:0006351//transcription, DNA-templated" gi|51093870|ref|NP_899009.2|/0/forkhead box protein N3 [Mus musculus] 245886 4164.87 4.333333333 3.99 -0.119088471 Down 0.196679078 Ankrd27 ankyrin repeat domain 27 (VPS9 domain) K20175|1|0.0|724|mmu:245886|ankyrin repeat domain-containing protein 27 GO:0005768//endosome GO:0008047//enzyme activator activity;GO:0005488//binding GO:0019222//regulation of metabolic process;GO:0016192//vesicle-mediated transport gi|125988393|ref|NP_663608.3|/0/ankyrin repeat domain-containing protein 27 isoform 1 [Mus musculus] 76793 2344 4.11 3.773333333 -0.123298842 Down 0.196679078 Snip1 Smad nuclear interacting protein 1 K13108|1|3e-165|584|mmu:76793|smad nuclear-interacting protein 1 GO:0031981//nuclear lumen GO:0005488//binding "GO:0006351//transcription, DNA-templated;GO:0035195//gene silencing by miRNA" gi|227430375|ref|NP_780455.2|/2.86415e-164/smad nuclear-interacting protein 1 [Mus musculus] 213760 3468 22.20666667 21.2 -0.066928589 Down 0.196679078 Prepl prolyl endopeptidase-like "K14210|1|4e-76|289|mmu:20532|solute carrier family 3 (neutral and basic amino acid transporter), member 1" GO:0044424;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part "GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity" GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process gi|254939518|ref|NP_001157094.1|/0/prolyl endopeptidase-like isoform a [Mus musculus] 14172 1546 4.086666667 4.43 0.116382126 Up 0.196679078 Fgf18 fibroblast growth factor 18 K04358|1|6e-96|353|myb:102262222|fibroblast growth factor GO:0031981//nuclear lumen;GO:0044421;GO:0031981//nuclear lumen;GO:0044421 GO:0005104//fibroblast growth factor receptor binding;GO:0005104//fibroblast growth factor receptor binding GO:0002062//chondrocyte differentiation;GO:0008283//cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0036072;GO:0036075;GO:0030323//respiratory tube development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0043410//positive regulation of MAPK cascade;GO:0002062//chondrocyte differentiation;GO:0008283//cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0036072;GO:0036075;GO:0030323//respiratory tube development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0043410//positive regulation of MAPK cascade gi|965979891|ref|XP_014956713.1|/4.83491e-95/PREDICTED: fibroblast growth factor 18 isoform X2 [Ovis aries] 77056 3361.26 8.346666667 7.84 -0.090346502 Down 0.196660273 Tmco4 transmembrane and coiled-coil domains 4 - GO:0031224//intrinsic component of membrane - - gi|21313340|ref|NP_084133.1|/0/transmembrane and coiled-coil domain-containing protein 4 [Mus musculus] 67392 2634.31 7.986666667 8.493333333 0.088737369 Up 0.196660273 4833420G17Rik RIKEN cDNA 4833420G17 gene - - - - gi|165905617|ref|NP_080403.4|/0/uncharacterized protein C5orf34 homolog [Mus musculus] 67220 1370 77.71666667 74.58333333 -0.059370747 Down 0.196613261 Plekho1 "pleckstrin homology domain containing, family O member 1" - GO:0043231//intracellular membrane-bounded organelle - - gi|12963637|ref|NP_075809.1|/0/pleckstrin homology domain-containing family O member 1 [Mus musculus] 52064 2001 75.01 71.88333333 -0.061425632 Down 0.196613261 Coq5 coenzyme Q5 methyltransferase "K06127|1|0.0|642|mmu:52064|2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.201]" - - - - 57257 3621.09 0.803333333 0.976666667 0.281867518 Up 0.196603859 Vav3 vav 3 oncogene K05730|1|8e-165|583|mmu:57257|guanine nucleotide exchange factor VAV GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044444//cytoplasmic part "GO:0008047//enzyme activator activity;GO:0030674//protein binding, bridging;GO:0070851//growth factor receptor binding;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity;GO:0030674//protein binding, bridging;GO:0070851//growth factor receptor binding;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity" GO:0043087//regulation of GTPase activity;GO:0042221//response to chemical;GO:0007266//Rho protein signal transduction;GO:0007599//hemostasis;GO:0007155//cell adhesion;GO:0012501//programmed cell death;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016192//vesicle-mediated transport;GO:0030031//cell projection assembly;GO:0033554//cellular response to stress;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0043087//regulation of GTPase activity;GO:0042221//response to chemical;GO:0007266//Rho protein signal transduction;GO:0007599//hemostasis;GO:0007155//cell adhesion;GO:0012501//programmed cell death;GO:0050851//antigen receptor-mediated signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0048870//cell motility;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016192//vesicle-mediated transport;GO:0030031//cell projection assembly;GO:0033554//cellular response to stress;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0043551//regulation of phosphatidylinositol 3-kinase activity gi|22165386|ref|NP_666251.1|/1.1711e-168/guanine nucleotide exchange factor VAV3 isoform 2 [Mus musculus] 22195 2609 75.83333333 78.90666667 0.057315056 Up 0.196566249 Ube2l3 ubiquitin-conjugating enzyme E2L 3 K04552|1|1e-79|300|chx:102187703|ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0032550;GO:0044389//ubiquitin-like protein ligase binding;GO:0003712//transcription cofactor activity;GO:0019787//ubiquitin-like protein transferase activity "GO:0000209//protein polyubiquitination;GO:0006351//transcription, DNA-templated;GO:0051384//response to glucocorticoid;GO:0000084//mitotic S phase;GO:0019941//modification-dependent protein catabolic process;GO:0032870//cellular response to hormone stimulus" gi|926713124|ref|XP_013826295.1|/9.37419e-79/PREDICTED: ubiquitin-conjugating enzyme E2 L3 [Capra hircus] 67278 1448 21.17333333 22.17666667 0.066794121 Up 0.196349994 Pagr1a PAXIP1 associated glutamate rich protein 1A K14973|1|5e-116|420|mmu:67278|PAXIP1-associated protein 1 - - - - 78178 392 0.14 0.25 0.836501268 Up 0.196284178 4930511A08Rik RIKEN cDNA 4930511A08 gene - - - - - 226982 7797 12.48 11.83666667 -0.076355075 Down 0.196274775 Eif5b eukaryotic translation initiation factor 5B K03243|1|0.0|1711|mmu:226982|translation initiation factor 5B - "GO:0008135//translation factor activity, RNA binding" GO:0006413//translational initiation gi|84043961|ref|NP_938045.2|/0/eukaryotic translation initiation factor 5B [Mus musculus] 67211 2014 6.066666667 6.483333333 0.095831705 Up 0.196265373 Armc10 armadillo repeat containing 10 - GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0040007//growth gi|12853546|dbj|BAB29775.1|/3.92689e-151/unnamed protein product [Mus musculus] 107723 6042.36 6.56 6.136666667 -0.096240594 Down 0.196265373 Slc12a6 "solute carrier family 12, member 6" "K14427|1|0.0|2096|mmu:107723|solute carrier family 12 (potassium/chloride transporter), member 4/5/6" GO:0044459;GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane GO:0015377//cation:chloride symporter activity GO:0015698//inorganic anion transport;GO:0042539//hypotonic salinity response gi|156766070|ref|NP_598410.2|/0/solute carrier family 12 member 6 isoform 2 [Mus musculus] 14169 2824 0.136666667 0.243333333 0.832272554 Up 0.196190154 Fgf14 fibroblast growth factor 14 K04358|1|2e-144|509|fca:101082119|fibroblast growth factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0070851//growth factor receptor binding;GO:0005539//glycosaminoglycan binding;GO:0070851//growth factor receptor binding;GO:0005539//glycosaminoglycan binding GO:0048731//system development;GO:0051403//stress-activated MAPK cascade;GO:0007267//cell-cell signaling;GO:0002028//regulation of sodium ion transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007626//locomotory behavior;GO:0050877//neurological system process;GO:0048731//system development;GO:0051403//stress-activated MAPK cascade;GO:0007267//cell-cell signaling;GO:0002028//regulation of sodium ion transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007626//locomotory behavior;GO:0050877//neurological system process gi|19224657|ref|NP_071559.2|/3.97463e-131/fibroblast growth factor 14 [Rattus norvegicus] 66661 3605 19.89666667 18.91 -0.07337739 Down 0.196190154 Srp72 signal recognition particle 72 K03108|1|0.0|1135|mmu:66661|signal recognition particle subunit SRP72 GO:0048500//signal recognition particle;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0003723//RNA binding;GO:0043021//ribonucleoprotein complex binding GO:0042221//response to chemical;GO:0006613//cotranslational protein targeting to membrane gi|118344452|ref|NP_079967.1|/0/signal recognition particle subunit SRP72 [Mus musculus] 67771 1897 20.18333333 21.17 0.06885681 Up 0.196190154 Arpc5 "actin related protein 2/3 complex, subunit 5" "K05754|1|9e-80|271|cfr:102509395|actin related protein 2/3 complex, subunit 5" GO:0031252//cell leading edge;GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity GO:0008064//regulation of actin polymerization or depolymerization gi|528753875|gb|EPY73534.1|/1.06209e-83/actin-related protein 2/3 complex subunit 5 [Camelus ferus] 52469 718 74.37333333 77.31666667 0.055994007 Up 0.196180751 Coa3 cytochrome C oxidase assembly factor 3 "K18175|1|2e-41|171|mmu:52469|cytochrome c oxidase assembly factor 3, animal type" GO:0031304//intrinsic component of mitochondrial inner membrane - GO:0010822//positive regulation of mitochondrion organization;GO:0008535//respiratory chain complex IV assembly "gi|21311867|ref|NP_080894.1|/1.24967e-40/cytochrome c oxidase assembly factor 3 homolog, mitochondrial [Mus musculus]" 13434 2637 2.12 1.883333333 -0.170775898 Down 0.196171349 Trdmt1 tRNA aspartic acid methyltransferase 1 K15336|1|0.0|791|mmu:13434|tRNA (cytosine38-C5)-methyltransferase [EC:2.1.1.204] GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0016741 GO:0006399//tRNA metabolic process;GO:0006305 gi|161016803|ref|NP_034197.3|/0/tRNA (cytosine(38)-C(5))-methyltransferase [Mus musculus] 70925 3494 1.883333333 2.123333333 0.173042505 Up 0.196171349 Cdkn2aip CDKN2A interacting protein - GO:0005730//nucleolus GO:0005515//protein binding GO:0010608//posttranscriptional regulation of gene expression;GO:0016049//cell growth;GO:0007165//signal transduction gi|27369527|ref|NP_765995.1|/0/CDKN2A-interacting protein [Mus musculus] 320739 3914 2.146666667 1.91 -0.168525549 Down 0.196171349 6530403H02Rik RIKEN cDNA 6530403H02 gene K11290|1|2e-16|81.3|rno:317165|template-activating factor I - - - - 14296 2614 1.94 2.176666667 0.166063839 Up 0.196171349 Frat1 frequently rearranged in advanced T cell lymphomas K03069|1|5e-119|431|mmu:14296|frequently rearranged in advanced T-cell lymphomas 1 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0006886//intracellular protein transport gi|37059812|ref|NP_032069.2|/4.61154e-118/proto-oncogene FRAT1 [Mus musculus] 71279 5240 1.916666667 2.153333333 0.167972209 Up 0.196171349 Slc29a3 "solute carrier family 29 (nucleoside transporters), member 3" "K15014|1|0.0|800|mmu:71279|solute carrier family 29 (equilibrative nucleoside transporter), member 1/2/3" GO:0005770//late endosome;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane GO:0015932//nucleobase-containing compound transmembrane transporter activity GO:0015931//nucleobase-containing compound transport gi|12963743|ref|NP_076085.1|/0/equilibrative nucleoside transporter 3 [Mus musculus] 244183 2771 0.023333333 0.106666667 2.192645078 Up 0.196114935 Trim30b tripartite motif-containing 30B K10648|1|3e-43|125|mmu:209387|tripartite motif-containing protein 5 [EC:2.3.2.27] - - - gi|28316738|ref|NP_783579.1|/3.67767e-89/tripartite motif-containing 30B [Mus musculus] 213121 4054 0.54 0.69 0.353636955 Up 0.19609613 Ankrd35 ankyrin repeat domain 35 K15502|1|7e-26|122|chx:102180432|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A - - - gi|124487271|ref|NP_001074608.1|/0/ankyrin repeat domain-containing protein 35 [Mus musculus] 330267 11019 0.683333333 0.536666667 -0.348563221 Down 0.19609613 Thsd7a "thrombospondin, type I, domain containing 7A" K08624|1|3e-62|245|sko:100370521|a disintegrin and metalloproteinase with thrombospondin motifs 9 [EC:3.4.24.-] - - - gi|50510729|dbj|BAD32350.1|/0/mKIAA0960 protein [Mus musculus] 12144 4598 0.353333333 0.23 -0.619395998 Down 0.19605852 Blm "Bloom syndrome, RecQ helicase-like" K10901|1|0.0|2412|mmu:12144|bloom syndrome protein [EC:3.6.4.12] GO:0034399//nuclear periphery;GO:0043073//germ cell nucleus;GO:0016604//nuclear body;GO:0000795//synaptonemal complex;GO:0034399//nuclear periphery;GO:0043073//germ cell nucleus;GO:0016604//nuclear body;GO:0000795//synaptonemal complex GO:0004003//ATP-dependent DNA helicase activity;GO:0032550;GO:0005515//protein binding;GO:0000217//DNA secondary structure binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0032550;GO:0005515//protein binding;GO:0000217//DNA secondary structure binding "GO:0006461//protein complex assembly;GO:0000019//regulation of mitotic recombination;GO:0006996//organelle organization;GO:0006351//transcription, DNA-templated;GO:0030217//T cell differentiation;GO:0009154//purine ribonucleotide catabolic process;GO:0065009;GO:0006974//cellular response to DNA damage stimulus;GO:0010212//response to ionizing radiation;GO:0000738//DNA catabolic process, exonucleolytic;GO:0048523//negative regulation of cellular process;GO:0042102//positive regulation of T cell proliferation;GO:0006461//protein complex assembly;GO:0000019//regulation of mitotic recombination;GO:0006996//organelle organization;GO:0006351//transcription, DNA-templated;GO:0030217//T cell differentiation;GO:0009154//purine ribonucleotide catabolic process;GO:0065009;GO:0006974//cellular response to DNA damage stimulus;GO:0010212//response to ionizing radiation;GO:0000738//DNA catabolic process, exonucleolytic;GO:0048523//negative regulation of cellular process;GO:0042102//positive regulation of T cell proliferation" gi|226693393|ref|NP_031576.4|/0/Bloom syndrome protein homolog isoform 1 [Mus musculus] 242341 2518 0.026666667 0.106666667 2 Up 0.196011509 Atp6v0d2 "ATPase, H+ transporting, lysosomal V0 subunit D2" K02146|1|0.0|710|mmu:242341|V-type H+-transporting ATPase subunit d GO:0005768//endosome;GO:0044459;GO:0033176//proton-transporting V-type ATPase complex;GO:0005774//vacuolar membrane GO:0015077//monovalent inorganic cation transmembrane transporter activity "GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient" gi|225543207|ref|NP_780615.2|/0/V-type proton ATPase subunit d 2 [Mus musculus] 71860 2201 0.11 0.026666667 -2.044394119 Down 0.196011509 Cfap52 cilia and flagella associated protein 52 K16482|1|2e-19|100|sko:100378584|centriolar protein POC1 - - - - 54167 3272 0.023333333 0.1 2.099535674 Up 0.196011509 Icos inducible T cell co-stimulator K06713|1|1e-106|390|mmu:54167|inducible T-cell co-stimulator GO:0009986//cell surface;GO:0016021//integral component of membrane - GO:0007155//cell adhesion;GO:0031294//lymphocyte costimulation gi|224809335|ref|NP_059508.2|/8.93935e-106/inducible T-cell costimulator precursor [Mus musculus] 223696 1024 64.01 66.82666667 0.062126605 Up 0.195973899 Tomm22 translocase of outer mitochondrial membrane 22 homolog (yeast) K17769|1|1e-26|122|ecb:100070131|mitochondrial import receptor subunit TOM22 GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0005741//mitochondrial outer membrane GO:0008565//protein transporter activity;GO:0005488//binding GO:0006626//protein targeting to mitochondrion;GO:0019538//protein metabolic process gi|149743291|ref|XP_001501664.1|/9.93643e-26/PREDICTED: mitochondrial import receptor subunit TOM22 homolog [Equus caballus] 101669761 994 0.253333333 0.143333333 -0.821662759 Down 0.195917485 Gm15694 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (B14.5a), pseudogene" K03951|1|5e-37|148|mmu:66416|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7 GO:0005746//mitochondrial respiratory chain GO:0050136//NADH dehydrogenase (quinone) activity GO:0051234//establishment of localization;GO:0022904//respiratory electron transport chain "gi|148678268|gb|EDL10215.1|/5.6988e-39/mCG22992, isoform CRA_b, partial [Mus musculus]" 78635 1090 0.143333333 0.253333333 0.821662759 Up 0.195917485 Kcnd3os "potassium voltage-gated channel, Shal-related family, member 3, opposite strand" - - - - - 74931 1590.16 19.63333333 18.65333333 -0.073871672 Down 0.195917485 4930481A15Rik RIKEN cDNA 4930481A15 gene K00419|1|1e-19|100|mmu:66152|ubiquinol-cytochrome c reductase subunit 9 GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain - GO:0051234//establishment of localization;GO:0022904//respiratory electron transport chain;GO:0051234//establishment of localization;GO:0022904//respiratory electron transport chain "gi|148701174|gb|EDL33121.1|/6.09479e-45/mCG1045479, isoform CRA_b [Mus musculus]" 54709 1127 66.42666667 69.21666667 0.059356945 Up 0.19589868 Eif3i "eukaryotic translation initiation factor 3, subunit I" K03246|1|0.0|686|hgl:101711310|translation initiation factor 3 subunit I GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0008135//translation factor activity, RNA binding" GO:0006412//translation gi|640816286|ref|XP_008064944.1|/0/PREDICTED: eukaryotic translation initiation factor 3 subunit I [Tarsius syrichta] 213498 5617 11.9 11.26666667 -0.078900828 Down 0.195814058 Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 K12331|1|0.0|2758|mmu:213498|Rho guanine nucleotide exchange factor 11 GO:0044424 - "GO:0007265//Ras protein signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0006351//transcription, DNA-templated" gi|51491850|ref|NP_001003912.1|/0/rho guanine nucleotide exchange factor 11 [Mus musculus] 68458 531 11.10666667 11.73333333 0.079187028 Up 0.195814058 Ppp1r14a "protein phosphatase 1, regulatory (inhibitor) subunit 14A" K12328|1|3e-46|186|mmu:68458|protein phosphatase 1 regulatory subunit 14A - - GO:0008152//metabolic process gi|27754044|ref|NP_081007.2|/2.21918e-45/protein phosphatase 1 regulatory subunit 14A [Mus musculus] 20535 4168.49 11.32 10.69 -0.082612105 Down 0.195814058 Slc4a2 "solute carrier family 4 (anion exchanger), member 2" "K13855|1|0.0|1976|mmu:20535|solute carrier family 4 (anion exchanger), member 2" GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane GO:0015301//anion:anion antiporter activity;GO:0015103//inorganic anion transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0015103//inorganic anion transmembrane transporter activity GO:0015698//inorganic anion transport;GO:0015698//inorganic anion transport gi|161169001|ref|NP_033233.2|/0/anion exchange protein 2 [Mus musculus] 14466 2079.06 8.076666667 8.576666667 0.086657052 Up 0.195767047 Gba "glucosidase, beta, acid" K01201|1|0.0|896|mmu:14466|glucosylceramidase [EC:3.2.1.45] GO:0005764//lysosome;GO:0005764//lysosome;GO:0005764//lysosome "GO:0005515//protein binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0005515//protein binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0005515//protein binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds" GO:0006670//sphingosine metabolic process;GO:0001818//negative regulation of cytokine production;GO:0009968//negative regulation of signal transduction;GO:0007033//vacuole organization;GO:0034612//response to tumor necrosis factor;GO:0050891//multicellular organismal water homeostasis;GO:0009628//response to abiotic stimulus;GO:0043405//regulation of MAP kinase activity;GO:0043588//skin development;GO:0031960//response to corticosteroid;GO:0006470//protein dephosphorylation;GO:0006678//glucosylceramide metabolic process;GO:0006670//sphingosine metabolic process;GO:0001818//negative regulation of cytokine production;GO:0009968//negative regulation of signal transduction;GO:0007033//vacuole organization;GO:0034612//response to tumor necrosis factor;GO:0050891//multicellular organismal water homeostasis;GO:0009628//response to abiotic stimulus;GO:0043405//regulation of MAP kinase activity;GO:0043588//skin development;GO:0031960//response to corticosteroid;GO:0006470//protein dephosphorylation;GO:0006678//glucosylceramide metabolic process;GO:0006670//sphingosine metabolic process;GO:0001818//negative regulation of cytokine production;GO:0009968//negative regulation of signal transduction;GO:0007033//vacuole organization;GO:0034612//response to tumor necrosis factor;GO:0050891//multicellular organismal water homeostasis;GO:0009628//response to abiotic stimulus;GO:0043405//regulation of MAP kinase activity;GO:0043588//skin development;GO:0031960//response to corticosteroid;GO:0006470//protein dephosphorylation;GO:0006678//glucosylceramide metabolic process "gi|148683282|gb|EDL15229.1|/0/glucosidase, beta, acid, isoform CRA_a, partial [Mus musculus]" 21454 2499 66.12333333 68.86 0.058506727 Up 0.195757644 Tcp1 t-complex protein 1 K09493|1|0.0|1071|mmu:21454|T-complex protein 1 subunit alpha GO:0030141//secretory granule;GO:0043234//protein complex;GO:0000790//nuclear chromatin;GO:0005813//centrosome;GO:0016020//membrane;GO:0030141//secretory granule;GO:0043234//protein complex;GO:0000790//nuclear chromatin;GO:0005813//centrosome;GO:0016020//membrane GO:0032550;GO:0005515//protein binding;GO:0032550;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0035036//sperm-egg recognition;GO:0007281//germ cell development;GO:0044267//cellular protein metabolic process;GO:0035036//sperm-egg recognition;GO:0007281//germ cell development gi|110625624|ref|NP_038714.2|/0/T-complex protein 1 subunit alpha isoform 1 [Mus musculus] 66249 1578 20.64666667 21.61333333 0.066012708 Up 0.195748242 Pno1 partner of NOB1 homolog K11884|1|1e-137|492|mmu:66249|RNA-binding protein PNO1 GO:0031981//nuclear lumen GO:0003676//nucleic acid binding - gi|13384846|ref|NP_079719.1|/8.94638e-137/RNA-binding protein PNO1 [Mus musculus] 65105 1182 20.31666667 21.28666667 0.067286332 Up 0.195748242 Arl6ip4 ADP-ribosylation factor-like 6 interacting protein 4 - - - - gi|21362283|ref|NP_653092.1|/9.66305e-71/ADP-ribosylation factor-like protein 6-interacting protein 4 [Mus musculus] 223433 2980 0.686666667 0.85 0.30785291 Up 0.195738839 Fam105a "family with sequence similarity 105, member A" K18343|1|3e-48|150|cmk:103183941|ubiquitin thioesterase otulin [EC:3.4.19.12] - - - "gi|148676950|gb|EDL08897.1|/3.82386e-158/cDNA sequence BC052328, isoform CRA_b, partial [Mus musculus]" 66119 979.68 60.85333333 63.56 0.062782834 Up 0.19566362 Tomm6 translocase of outer mitochondrial membrane 6 homolog (yeast) K17772|1|2e-24|115|mmu:66119|mitochondrial import receptor subunit TOM6 GO:0031966//mitochondrial membrane;GO:0031966//mitochondrial membrane - GO:0019538//protein metabolic process;GO:0006605//protein targeting;GO:0019538//protein metabolic process;GO:0006605//protein targeting gi|13384732|ref|NP_079641.1|/1.59435e-23/mitochondrial import receptor subunit TOM6 homolog [Mus musculus] 226422 1212 4.653333333 5.026666667 0.111337487 Up 0.195578999 Rab29 "RAB29, member RAS oncogene family" K07916|1|2e-114|415|mmu:226422|Ras-related protein Rab-7L1 GO:0016020//membrane GO:0032550 GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0045184//establishment of protein localization gi|229608951|ref|NP_659124.2|/1.25874e-113/ras-related protein Rab-7L1 [Mus musculus] 192678 3425 58.97666667 61.62333333 0.063332439 Up 0.195569596 Rassf3 Ras association (RalGDS/AF-6) domain family member 3 K09852|1|2e-116|423|mmu:192678|Ras association domain-containing protein 3 GO:0016020//membrane;GO:0015630//microtubule cytoskeleton GO:0005515//protein binding GO:0007154//cell communication gi|20336742|ref|NP_620406.1|/1.70736e-115/ras association domain-containing protein 3 [Mus musculus] 53325 5459.62 1.94 1.71 -0.182060327 Down 0.195541389 Banp BTG3 associated nuclear protein - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0033365//protein localization to organelle;GO:0009895;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization;GO:0032502//developmental process;GO:0033365//protein localization to organelle;GO:0009895;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization;GO:0032502//developmental process;GO:0033365//protein localization to organelle;GO:0009895;GO:0033365//protein localization to organelle;GO:0009895" gi|537194524|gb|ERE77808.1|/0/protein BANP isoform 1 [Cricetulus griseus] 170829 1390 1.976666667 1.743333333 -0.181221158 Down 0.195541389 Tram2 translocating chain-associating membrane protein 2 K14010|1|3e-113|411|lcm:102353958|translocating chain-associated membrane protein 1 GO:0031224//intrinsic component of membrane - GO:0045184//establishment of protein localization;GO:0009059//macromolecule biosynthetic process gi|28916683|ref|NP_803128.1|/0/translocating chain-associated membrane protein 2 [Mus musculus] 66540 3148 1.723333333 1.953333333 0.180736384 Up 0.195541389 Fam107b "family with sequence similarity 107, member B" - - - - gi|74220037|dbj|BAE40596.1|/3.16821e-76/unnamed protein product [Mus musculus] 22367 3712.59 2.103333333 2.35 0.159983252 Up 0.195494377 Vrk1 vaccinia related kinase 1 K08816|1|0.0|870|mmu:22367|vaccinia related kinase [EC:2.7.11.1] GO:0043232;GO:0044431//Golgi apparatus part;GO:0031981//nuclear lumen;GO:0043232;GO:0044431//Golgi apparatus part;GO:0031981//nuclear lumen;GO:0043232;GO:0044431//Golgi apparatus part GO:0032550;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0032550;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0032550;GO:0004672//protein kinase activity;GO:0005515//protein binding GO:0006468//protein phosphorylation;GO:0000087//mitotic M phase;GO:0007030//Golgi organization;GO:0006468//protein phosphorylation;GO:0000087//mitotic M phase;GO:0007030//Golgi organization;GO:0006468//protein phosphorylation;GO:0000087//mitotic M phase;GO:0007030//Golgi organization "gi|148686794|gb|EDL18741.1|/0/vaccinia related kinase 1, isoform CRA_b, partial [Mus musculus]" 16328 7964.29 2.43 2.176666667 -0.158835823 Down 0.195494377 Cep250 centrosomal protein 250 K16464|1|0.0|3652|mmu:16328|centrosomal protein CEP250 - - - "gi|148674210|gb|EDL06157.1|/0/mCG5221, partial [Mus musculus]" 240880 4293.02 2.08 2.33 0.163746427 Up 0.195494377 Scyl3 SCY1-like 3 (S. cerevisiae) K17542|1|0.0|951|mmu:240880|SCY1-like protein 3 GO:0031252//cell leading edge;GO:0043231//intracellular membrane-bounded organelle;GO:0031252//cell leading edge;GO:0043231//intracellular membrane-bounded organelle;GO:0031252//cell leading edge;GO:0043231//intracellular membrane-bounded organelle GO:0016740//transferase activity;GO:0032550;GO:0016740//transferase activity;GO:0032550;GO:0016740//transferase activity;GO:0032550 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process gi|553727163|ref|NP_001272931.1|/0/protein-associating with the carboxyl-terminal domain of ezrin isoform 2 [Mus musculus] 73736 748 20.6 19.63666667 -0.069094285 Down 0.195484975 Fcf1 FCF1 rRNA processing protein K14566|1|4e-101|369|mmu:73736|U3 small nucleolar RNA-associated protein 24 - - - - 100033459 2987 1.113333333 0.933333333 -0.254421276 Down 0.195428561 Pydc3 pyrin domain containing 3 K10955|1|2e-08|64.3|pale:102882303|intestinal mucin-2;K13908|4|4e-08|63.2|mcc:720912|mucin-5B - - - gi|242397472|ref|NP_001156410.1|/0/pyrin domain-containing protein 3 [Mus musculus] 18107 1838 61.25666667 63.85 0.059819756 Up 0.195400354 Nmt1 N-myristoyltransferase 1 K00671|1|0.0|991|mmu:18107|glycylpeptide N-tetradecanoyltransferase [EC:2.3.1.97] GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0016410//N-acyltransferase activity GO:0006498;GO:0012501//programmed cell death;GO:0044764;GO:0043009//chordate embryonic development;GO:0018065//protein-cofactor linkage gi|6679082|ref|NP_032733.1|/0/glycylpeptide N-tetradecanoyltransferase 1 [Mus musculus] 209737 4840 0.346666667 0.23 -0.591915261 Down 0.195390951 Kif15 kinesin family member 15 K10400|1|0.0|2573|mmu:209737|kinesin family member 15 GO:0015630//microtubule cytoskeleton GO:0003774//motor activity;GO:0032550 GO:0006928//movement of cell or subcellular component gi|39930325|ref|NP_034750.1|/0/kinesin-like protein KIF15 [Mus musculus] 319722 6712 0.23 0.346666667 0.591915261 Up 0.195390951 E330033B04Rik RIKEN cDNA E330033B04 gene - - - - "gi|67975423|ref|XP_668908.1|/2.44485e-15/hypothetical protein [Plasmodium berghei strain ANKA], partial [Plasmodium berghei ANKA]" 70967 2312.8 0.833333333 1.003333333 0.267835392 Up 0.195381549 Eva1c eva-1 homolog C (C. elegans) - - - - - 381066 2600 1.006666667 0.836666667 -0.266861185 Down 0.195381549 Zfp948 zinc finger protein 948 K09228|1|0.0|1414|mmu:381066|KRAB domain-containing zinc finger protein - - - - 12468 2452 61.22666667 63.81 0.059622393 Up 0.195362744 Cct7 "chaperonin containing Tcp1, subunit 7 (eta)" K09499|1|0.0|1064|mmu:12468|T-complex protein 1 subunit eta GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0032550;GO:0005515//protein binding GO:0051084//'de novo' posttranslational protein folding;GO:0035036//sperm-egg recognition gi|238814391|ref|NP_031664.3|/0/T-complex protein 1 subunit eta [Mus musculus] 381886 3700 64.95333333 67.52333333 0.05598256 Up 0.195353342 Mrgpra6 "MAS-related GPR, member A6" K08396|1|7e-77|291|mmu:668725|Mas-related G protein-coupled receptor member X - - - - 19341 1427 10.85333333 11.47333333 0.080146398 Up 0.195287525 Rab4a "RAB4A, member RAS oncogene family" K07879|1|8e-121|436|mmu:19341|Ras-related protein Rab-4A GO:0016020//membrane;GO:0030141//secretory granule;GO:0005768//endosome GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0000149//SNARE binding;GO:0008047//enzyme activator activity;GO:0022892//substrate-specific transporter activity;GO:0035254//glutamate receptor binding;GO:0019899//enzyme binding GO:0007265//Ras protein signal transduction;GO:0043462//regulation of ATPase activity;GO:0006897//endocytosis;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process gi|171184402|ref|NP_033029.2|/6.64045e-120/ras-related protein Rab-4A [Mus musculus] 12651 1768 10.99 10.37333333 -0.083311827 Down 0.195287525 Chkb choline kinase beta K14156|1|0.0|454|mmu:12651|choline/ethanolamine kinase [EC:2.7.1.32 2.7.1.82] GO:0044444//cytoplasmic part;GO:0044424;GO:0044444//cytoplasmic part GO:0032550;GO:0016301//kinase activity;GO:0032550;GO:0016301//kinase activity;GO:0032550;GO:0016301//kinase activity GO:0006656//phosphatidylcholine biosynthetic process;GO:0046337//phosphatidylethanolamine metabolic process;GO:0048513//animal organ development;GO:0006656//phosphatidylcholine biosynthetic process;GO:0046337//phosphatidylethanolamine metabolic process;GO:0048513//animal organ development;GO:0006656//phosphatidylcholine biosynthetic process;GO:0046337//phosphatidylethanolamine metabolic process;GO:0048513//animal organ development gi|6671748|ref|NP_031718.1|/0/choline/ethanolamine kinase [Mus musculus] 19280 6195.5 11.96 11.33666667 -0.077220884 Down 0.195287525 Ptprs "protein tyrosine phosphatase, receptor type, S" K06778|1|0.0|2932|cge:100770533|receptor-type tyrosine-protein phosphatase S [EC:3.1.3.48] GO:0031224//intrinsic component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0004721//phosphoprotein phosphatase activity;GO:0005488//binding;GO:0004725//protein tyrosine phosphatase activity;GO:0005488//binding;GO:0004725//protein tyrosine phosphatase activity;GO:0005488//binding;GO:0004725//protein tyrosine phosphatase activity GO:0022037//metencephalon development;GO:0022610;GO:0006470//protein dephosphorylation;GO:0021543//pallium development;GO:0022037//metencephalon development;GO:0006470//protein dephosphorylation;GO:0022610;GO:0021543//pallium development;GO:0022037//metencephalon development;GO:0006470//protein dephosphorylation;GO:0022610;GO:0021543//pallium development;GO:0022037//metencephalon development;GO:0006470//protein dephosphorylation;GO:0022610;GO:0021543//pallium development gi|158711690|ref|NP_035348.2|/0/receptor-type tyrosine-protein phosphatase S isoform 1 precursor [Mus musculus] 68839 2480 11.29666667 11.91333333 0.076679998 Up 0.195287525 Ankrd46 ankyrin repeat domain 46 K10380|1|3e-13|80.1|crg:105334014|ankyrin;K08803|5|5e-11|72.8|lcm:102361878|death-associated protein kinase [EC:2.7.11.1] GO:0031224//intrinsic component of membrane - - gi|29789417|ref|NP_780343.1|/1.4859e-118/ankyrin repeat domain-containing protein 46 [Mus musculus] 21813 4754.07 18.77666667 19.72666667 0.071206225 Up 0.195240513 Tgfbr2 "transforming growth factor, beta receptor II" K04388|1|0.0|1138|mmu:21813|TGF-beta receptor type-2 [EC:2.7.11.30] GO:0009986//cell surface;GO:0043234//protein complex;GO:0044459;GO:0016021//integral component of membrane;GO:0044444//cytoplasmic part;GO:0009986//cell surface;GO:0043234//protein complex;GO:0005887//integral component of plasma membrane;GO:0044444//cytoplasmic part GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005160//transforming growth factor beta receptor binding;GO:0032550;GO:0097367//carbohydrate derivative binding;GO:0019901//protein kinase binding;GO:0019838//growth factor binding;GO:0043169//cation binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005160//transforming growth factor beta receptor binding;GO:0032550;GO:0097367//carbohydrate derivative binding;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0019838//growth factor binding;GO:0043169//cation binding;GO:0046983//protein dimerization activity GO:0048704//embryonic skeletal system morphogenesis;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0072593//reactive oxygen species metabolic process;GO:0040007//growth;GO:0002517//T cell tolerance induction;GO:0002513//tolerance induction to self antigen;GO:0006897//endocytosis;GO:0001773//myeloid dendritic cell activation;GO:0043010//camera-type eye development;GO:0036314;GO:0022612//gland morphogenesis;GO:0008285//negative regulation of cell proliferation;GO:0007417//central nervous system development;GO:0010631//epithelial cell migration;GO:0001525//angiogenesis;GO:0001865//NK T cell differentiation;GO:0048645//organ formation;GO:0030323//respiratory tube development;GO:0002514;GO:0045860//positive regulation of protein kinase activity;GO:0012501//programmed cell death;GO:0048704//embryonic skeletal system morphogenesis;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0043403//skeletal muscle tissue regeneration;GO:0031667//response to nutrient levels;GO:0072593//reactive oxygen species metabolic process;GO:0002517//T cell tolerance induction;GO:0002513//tolerance induction to self antigen;GO:0006897//endocytosis;GO:0001773//myeloid dendritic cell activation;GO:0043010//camera-type eye development;GO:0036314;GO:0022612//gland morphogenesis;GO:0008285//negative regulation of cell proliferation;GO:0048545//response to steroid hormone;GO:0007417//central nervous system development;GO:0010631//epithelial cell migration;GO:0001525//angiogenesis;GO:0001865//NK T cell differentiation;GO:0009746;GO:0048645//organ formation;GO:0030323//respiratory tube development;GO:0002514;GO:0045860//positive regulation of protein kinase activity;GO:0012501//programmed cell death gi|239787884|ref|NP_083851.3|/0/TGF-beta receptor type-2 isoform 2 precursor [Mus musculus] 11545 3845 20.10666667 21.06 0.066831508 Up 0.195240513 Parp1 "poly (ADP-ribose) polymerase family, member 1" K10798|1|0.0|1838|mmu:11545|poly [ADP-ribose] polymerase [EC:2.4.2.30] GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0012505//endomembrane system "GO:0046914//transition metal ion binding;GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0016763//transferase activity, transferring pentosyl groups;GO:0046332//SMAD binding" GO:0032868//response to insulin;GO:0006366//transcription from RNA polymerase II promoter;GO:0016485//protein processing;GO:0040008//regulation of growth;GO:0043388//positive regulation of DNA binding;GO:0007184//SMAD protein import into nucleus;GO:0006281//DNA repair;GO:0006471//protein ADP-ribosylation gi|74198526|dbj|BAE39743.1|/0/unnamed protein product [Mus musculus] 77041 3657 1.333333333 1.14 -0.226003675 Down 0.195221708 Arsk arylsulfatase K K12376|1|0.0|1051|mmu:77041|arylsulfatase K [EC:3.1.6.-] - "GO:0016788//hydrolase activity, acting on ester bonds;GO:0043169//cation binding" - gi|221222633|sp|Q9D2L1.2|ARSK_MOUSE/0/RecName: Full=Arylsulfatase K; Short=ASK; Flags: Precursor 16905 2441.38 65.14666667 67.68 0.055038206 Up 0.195193501 Lmna lamin A K12641|1|2e-174|614|mmu:16905|lamin A/C GO:0034399//nuclear periphery;GO:0005882//intermediate filament;GO:0012505//endomembrane system;GO:0044444//cytoplasmic part;GO:0034399//nuclear periphery;GO:0005882//intermediate filament;GO:0012505//endomembrane system;GO:0044444//cytoplasmic part;GO:0034399//nuclear periphery;GO:0005882//intermediate filament;GO:0012505//endomembrane system;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0000226//microtubule cytoskeleton organization;GO:0007163//establishment or maintenance of cell polarity;GO:0006915//apoptotic process;GO:0001666//response to hypoxia;GO:0048522;GO:0006997//nucleus organization;GO:0048232//male gamete generation;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0006606//protein import into nucleus;GO:0016477//cell migration;GO:0000226//microtubule cytoskeleton organization;GO:0007163//establishment or maintenance of cell polarity;GO:0006915//apoptotic process;GO:0001666//response to hypoxia;GO:0048522;GO:0006997//nucleus organization;GO:0048232//male gamete generation;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0006606//protein import into nucleus;GO:0016477//cell migration;GO:0000226//microtubule cytoskeleton organization;GO:0007163//establishment or maintenance of cell polarity;GO:0006915//apoptotic process;GO:0022411;GO:0001666//response to hypoxia;GO:0048522;GO:0006997//nucleus organization;GO:0048232//male gamete generation;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0006606//protein import into nucleus;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0016477//cell migration gi|9506843|ref|NP_062263.1|/3.69384e-180/prelamin-A/C isoform C2 [Mus musculus] 94176 6431 0.546666667 0.693333333 0.342887714 Up 0.195137087 Dock2 dedicator of cyto-kinesis 2 K12367|1|0.0|3574|mmu:94176|dedicator of cytokinesis protein 2 GO:0043232;GO:0044444//cytoplasmic part GO:0005102//receptor binding;GO:0046906//tetrapyrrole binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity GO:0007010//cytoskeleton organization;GO:0006909//phagocytosis;GO:0042221//response to chemical;GO:0001767;GO:0006907//pinocytosis;GO:0044764;GO:0043368//positive T cell selection;GO:0031580//membrane raft distribution;GO:0050688//regulation of defense response to virus;GO:0001773//myeloid dendritic cell activation;GO:0009988//cell-cell recognition;GO:0043383//negative T cell selection;GO:0035556//intracellular signal transduction;GO:0042098//T cell proliferation gi|117553625|ref|NP_203538.2|/0/dedicator of cytokinesis protein 2 [Mus musculus] 18094 1260 0.05 0.143333333 1.519374159 Up 0.195137087 Nkx2-9 NK2 homeobox 9 K09347|1|8e-122|439|mmu:18094|homeobox protein Nkx-2.8 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0043566//structure-specific DNA binding "GO:0030323//respiratory tube development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0008285//negative regulation of cell proliferation;GO:0006351//transcription, DNA-templated" gi|111154095|ref|NP_032727.2|/6.5744e-121/homeobox protein Nkx-2.8 [Mus musculus] 14632 3662 0.706666667 0.556666667 -0.344216162 Down 0.195137087 Gli1 GLI-Kruppel family member GLI1 K16797|1|0.0|1957|mmu:14632|zinc finger protein GLI1 GO:0005929//cilium;GO:0044444//cytoplasmic part "GO:0046914//transition metal ion binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000975//regulatory region DNA binding;GO:0015631//tubulin binding" GO:0021536//diencephalon development;GO:0008544//epidermis development;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0001503//ossification;GO:0048570//notochord morphogenesis;GO:0003002//regionalization;GO:0030178//negative regulation of Wnt signaling pathway;GO:0007224//smoothened signaling pathway;GO:0030323//respiratory tube development;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006260//DNA replication gi|90186273|ref|NP_034426.2|/0/zinc finger protein GLI1 [Mus musculus] 107684 3887 0.73 0.576666667 -0.340158832 Down 0.195137087 Coro2a "coronin, actin binding protein 2A" K13887|1|0.0|1039|mmu:107684|coronin-2 - - - - 93884 3693 0.143333333 0.05 -1.519374159 Down 0.195137087 Pcdhb13 protocadherin beta 13 K16494|1|0.0|1499|mmu:93884|protocadherin beta GO:0031224//intrinsic component of membrane - GO:0022610 gi|18087789|ref|NP_444368.1|/0/protocadherin beta-6 precursor [Mus musculus] 231510 2877 5.53 5.94 0.103183451 Up 0.19510888 Agpat9 1-acylglycerol-3-phosphate O-acyltransferase 9 K13506|1|0.0|857|mmu:231510|glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15] - - - - 20375 1473 5.516666667 5.93 0.104235294 Up 0.19510888 Spi1 spleen focus forming virus (SFFV) proviral integration oncogene K09438|1|5e-127|457|cge:100763362|transcription factor PU.1 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001228//transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding;GO:0008134//transcription factor binding" GO:0009653//anatomical structure morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0010629//negative regulation of gene expression;GO:0002573//myeloid leukocyte differentiation;GO:0010558;GO:0019827//stem cell population maintenance;GO:0035067//negative regulation of histone acetylation;GO:0012502//induction of programmed cell death;GO:0030218//erythrocyte differentiation;GO:0044026//DNA hypermethylation;GO:0001773//myeloid dendritic cell activation;GO:0002244//hematopoietic progenitor cell differentiation gi|354469958|ref|XP_003497379.1|/3.80104e-126/PREDICTED: LOW QUALITY PROTEIN: transcription factor PU.1 isoform X1 [Cricetulus griseus] 56381 12299 7.886666667 7.396666667 -0.092540406 Down 0.195043063 Spen "SPEN homolog, transcriptional regulator (Drosophila)" K13190|1|1e-110|405|acs:100564121|RNA-binding protein 15;K15348|5|2e-31|143|ssc:100522681|pleckstrin homology domain-containing family M member 2 - - - gi|120587001|ref|NP_062737.2|/0/msx2-interacting protein [Mus musculus] 105171 4102 8.293333333 7.806666667 -0.08724541 Down 0.195043063 Arrdc3 arrestin domain containing 3 "K09364|1|3e-11|74.3|gja:107122555|POU domain transcription factor, class 2" GO:0044424 GO:0031690//adrenergic receptor binding GO:0040013//negative regulation of locomotion;GO:0031649//heat generation;GO:0009892//negative regulation of metabolic process;GO:0060612//adipose tissue development;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway gi|28972730|dbj|BAC65781.1|/0/mKIAA1376 protein [Mus musculus] 83493 3433 8.066666667 7.58 -0.089774793 Down 0.195043063 Sacm1l SAC1 suppressor of actin mutations 1-like (yeast) K20279|1|3e-52|209|xtr:100487517|synaptojanin [EC:3.1.3.36] GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0008328//ionotropic glutamate receptor complex GO:0052744//phosphatidylinositol monophosphate phosphatase activity GO:0046488//phosphatidylinositol metabolic process;GO:0046474//glycerophospholipid biosynthetic process gi|28972437|dbj|BAC65672.1|/0/mKIAA0851 protein [Mus musculus] 75612 3855 55.29333333 57.75333333 0.06279867 Up 0.195024258 Gns glucosamine (N-acetyl)-6-sulfatase K01137|1|0.0|1056|mmu:75612|N-acetylglucosamine-6-sulfatase [EC:3.1.6.14] GO:0000323//lytic vacuole GO:0008484//sulfuric ester hydrolase activity;GO:0043169//cation binding;GO:0097367//carbohydrate derivative binding;GO:0043168//anion binding GO:0006027//glycosaminoglycan catabolic process "gi|148692470|gb|EDL24417.1|/0/glucosamine (N-acetyl)-6-sulfatase, isoform CRA_b, partial [Mus musculus]" 214572 2269 19.65333333 20.59666667 0.067636849 Up 0.195014856 Prmt7 protein arginine N-methyltransferase 7 K11438|1|0.0|1437|mmu:214572|type III protein arginine methyltransferase [EC:2.1.1.321] - - - - 56389 1996.32 19.23666667 20.17333333 0.068590657 Up 0.195014856 Stx5a syntaxin 5A K08490|1|3e-172|608|mmu:56389|syntaxin 5 GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0012505//endomembrane system GO:0005515//protein binding;GO:0005515//protein binding GO:0006906//vesicle fusion;GO:0016482//cytosolic transport;GO:0015031//protein transport;GO:0006906//vesicle fusion;GO:0016482//cytosolic transport;GO:0015031//protein transport gi|268370181|ref|NP_062803.4|/2.13918e-171/syntaxin-5 [Mus musculus] 17390 3078 20.79 19.85333333 -0.066508505 Down 0.195014856 Mmp2 matrix metallopeptidase 2 K01398|1|0.0|1337|mmu:17390|matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24] GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0044421;GO:0031012//extracellular matrix GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0044703;GO:0009605//response to external stimulus;GO:0007155//cell adhesion;GO:0040007//growth;GO:0001568//blood vessel development;GO:0008585//female gonad development;GO:0006915//apoptotic process;GO:0019229//regulation of vasoconstriction;GO:0022411;GO:0000302//response to reactive oxygen species;GO:0031103//axon regeneration;GO:0002009//morphogenesis of an epithelium;GO:0036072;GO:0009628//response to abiotic stimulus;GO:0043200//response to amino acid;GO:0048705//skeletal system morphogenesis;GO:0070555//response to interleukin-1;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0043062//extracellular structure organization;GO:0032963//collagen metabolic process;GO:0016477//cell migration;GO:0032355//response to estradiol;GO:0019538//protein metabolic process gi|6678902|ref|NP_032636.1|/0/72 kDa type IV collagenase preproprotein [Mus musculus] 110891 4252 0.576666667 0.433333333 -0.412260415 Down 0.194958441 Slc8a2 "solute carrier family 8 (sodium/calcium exchanger), member 2" K05849|1|0.0|1699|mmu:110891|solute carrier family 8 (sodium/calcium exchanger) - - - - 240697 2553 2.406666667 2.67 0.149803406 Up 0.194920832 Mcmdc2 minichromosome maintenance domain containing 2 K10738|1|2e-10|70.5|cin:100175750|DNA helicase MCM9 [EC:3.6.4.12] - GO:0003676//nucleic acid binding;GO:0032550 GO:0006259//DNA metabolic process gi|183227685|ref|NP_808390.2|/0/MCM domain-containing protein 2 [Mus musculus] 228061 7375 2.553333333 2.296666667 -0.152840409 Down 0.194920832 Agps alkylglycerone phosphate synthase K00803|1|0.0|1278|mmu:228061|alkyldihydroxyacetonephosphate synthase [EC:2.5.1.26] GO:0044439 "GO:0050660//flavin adenine dinucleotide binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups" GO:0050896//response to stimulus;GO:0046485//ether lipid metabolic process "gi|295444834|ref|NP_766254.2|/0/alkyldihydroxyacetonephosphate synthase, peroxisomal [Mus musculus]" 276852 2228 2.63 2.366666667 -0.152206276 Down 0.194920832 D11Wsu47e "DNA segment, Chr 11, Wayne State University 47, expressed" - GO:0031224//intrinsic component of membrane - - "gi|148702469|gb|EDL34416.1|/0/DNA segment, Chr 11, Wayne State University 47, expressed, isoform CRA_a, partial [Mus musculus]" 243538 2141 0.146666667 0.253333333 0.788495895 Up 0.194920832 Cfap100 cilia and flagella associated protein 100 - - - - gi|254939666|ref|NP_776136.2|/0/coiled-coil domain-containing protein 37 [Mus musculus] 77781 7273 2.333333333 2.59 0.150559677 Up 0.194920832 Epm2aip1 EPM2A (laforin) interacting protein 1 K09228|1|1e-68|265|gja:107122456|KRAB domain-containing zinc finger protein;K18633|2|1e-12|79.7|cmy:102936197|mitotic-spindle organizing protein 1;K13373|3|4e-12|78.2|cmy:102944731|17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270];K09503|4|8e-06|57.0|pss:102449121|DnaJ homolog subfamily A member 2 GO:0043231//intracellular membrane-bounded organelle - - "gi|148677026|gb|EDL08973.1|/0/EPM2A (laforin) interacting protein 1, isoform CRA_a, partial [Mus musculus]" 268822 2052 2.643333333 2.383333333 -0.149377624 Down 0.194920832 Adck5 aarF domain containing kinase 5 K08869|1|0.0|914|mmu:268822|aarF domain-containing kinase GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0004672//protein kinase activity;GO:0004672//protein kinase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|169234776|ref|NP_766548.2|/0/uncharacterized aarF domain-containing protein kinase 5 [Mus musculus] 240028 5181 3.576666667 3.273333333 -0.127855146 Down 0.194902027 Lnpep leucyl/cystinyl aminopeptidase K01257|1|0.0|1961|mmu:240028|cystinyl aminopeptidase [EC:3.4.11.3] GO:0031224//intrinsic component of membrane;GO:0030141//secretory granule;GO:0044297//cell body GO:0042277//peptide binding;GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity GO:0009719;GO:0043171//peptide catabolic process;GO:0048168//regulation of neuronal synaptic plasticity;GO:0019538//protein metabolic process;GO:0009057//macromolecule catabolic process;GO:0007186//G-protein coupled receptor signaling pathway gi|27370240|ref|NP_766415.1|/0/leucyl-cystinyl aminopeptidase [Mus musculus] 108062 4133.9 3.126666667 3.43 0.133583154 Up 0.194902027 Cstf2 "cleavage stimulation factor, 3' pre-RNA subunit 2" K14407|1|0.0|741|mmu:108062|cleavage stimulation factor subunit 2 GO:0005849//mRNA cleavage factor complex;GO:0016604//nuclear body;GO:0005849//mRNA cleavage factor complex;GO:0016604//nuclear body;GO:0005849//mRNA cleavage factor complex;GO:0016604//nuclear body GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - gi|18875338|ref|NP_573459.1|/0/cleavage stimulation factor subunit 2 [Mus musculus] 654822 1484 3.82 4.15 0.119538698 Up 0.194892625 D330041H03Rik RIKEN cDNA D330041H03 gene - - - - gi|148690367|gb|EDL22314.1|/6.96286e-35/mCG1051026 [Mus musculus] 27057 4032.38 20.96666667 20.04 -0.065215008 Down 0.194742187 Ncoa4 nuclear receptor coactivator 4 K09289|1|0.0|1213|mmu:27057|nuclear receptor coactivator 4 - - - - 67738 1728 19.17333333 20.1 0.068094326 Up 0.194742187 Ppid peptidylprolyl isomerase D (cyclophilin D) K05864|1|0.0|690|mmu:67738|peptidyl-prolyl isomerase D [EC:5.2.1.8] GO:0031981//nuclear lumen;GO:0005856//cytoskeleton GO:0033218//amide binding;GO:0005527//macrolide binding;GO:0031072//heat shock protein binding;GO:0035258//steroid hormone receptor binding;GO:0016859//cis-trans isomerase activity GO:0006457//protein folding;GO:0018208//peptidyl-proline modification;GO:0006366//transcription from RNA polymerase II promoter;GO:0009306//protein secretion;GO:0019079//viral genome replication;GO:0006915//apoptotic process;GO:0006996//organelle organization;GO:0065003;GO:0034644//cellular response to UV;GO:0006950//response to stress;GO:0042391//regulation of membrane potential gi|13385854|ref|NP_080628.1|/0/peptidyl-prolyl cis-trans isomerase D [Mus musculus] 234395 3549 20.14333333 19.21666667 -0.067944334 Down 0.194742187 Ushbp1 Usher syndrome 1C binding protein 1 - - GO:0019904//protein domain specific binding - "gi|148696967|gb|EDL28914.1|/0/Usher syndrome 1C binding protein 1, partial [Mus musculus]" 223691 1893 54.51666667 56.89666667 0.06164678 Up 0.194723382 Eif3l "eukaryotic translation initiation factor 3, subunit L" K15029|1|0.0|1058|mmu:223691|translation initiation factor 3 subunit L GO:0044452//nucleolar part;GO:0043234//protein complex "GO:0008135//translation factor activity, RNA binding" GO:0006412//translation gi|51093840|ref|NP_660121.2|/0/eukaryotic translation initiation factor 3 subunit L [Mus musculus] 233904 5934 11.73666667 11.12666667 -0.077001273 Down 0.194657565 Setd1a SET domain containing 1A K11422|1|0.0|1335|mmu:233904|histone-lysine N-methyltransferase SETD1 [EC:2.1.1.43] - - - gi|119508422|ref|NP_821172.2|/0/histone-lysine N-methyltransferase SETD1A [Mus musculus] 114142 6360 0.143333333 0.053333333 -1.426264755 Down 0.194648163 Foxp2 forkhead box P2 K09409|1|0.0|798|ecb:100055896|forkhead box protein P - - - gi|664726516|ref|XP_008520397.1|/0/PREDICTED: forkhead box protein P2 [Equus przewalskii] 14748 2159 0.136666667 0.05 -1.450661409 Down 0.194648163 Gpr3 G-protein coupled receptor 3 K04311|1|4e-150|534|mmu:14748|G protein-coupled receptor 3 GO:0016021//integral component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007126//meiotic nuclear division;GO:0046058//cAMP metabolic process;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0051480//regulation of cytosolic calcium ion concentration gi|6680065|ref|NP_032180.1|/3.06507e-149/G-protein coupled receptor 3 [Mus musculus] 14165 4572 0.143333333 0.053333333 -1.426264755 Down 0.194648163 Fgf10 fibroblast growth factor 10 K04358|1|5e-105|385|mmu:14165|fibroblast growth factor GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0044421 GO:0005539//glycosaminoglycan binding;GO:0005104//fibroblast growth factor receptor binding GO:0006915//apoptotic process;GO:0003156//regulation of organ formation;GO:0006281//DNA repair;GO:0001568//blood vessel development;GO:0001934//positive regulation of protein phosphorylation;GO:0044058//regulation of digestive system process;GO:0009855//determination of bilateral symmetry;GO:0002237//response to molecule of bacterial origin;GO:0021536//diencephalon development;GO:0035107//appendage morphogenesis;GO:0030335//positive regulation of cell migration;GO:0007589//body fluid secretion;GO:0010092//specification of organ identity;GO:0007050//cell cycle arrest;GO:0001942//hair follicle development;GO:0032924//activin receptor signaling pathway;GO:0007219//Notch signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0045444//fat cell differentiation;GO:0042692//muscle cell differentiation;GO:0048771//tissue remodeling;GO:0060445//branching involved in salivary gland morphogenesis;GO:0043010//camera-type eye development;GO:0043462//regulation of ATPase activity;GO:0060495;GO:0070343;GO:0035112//genitalia morphogenesis;GO:0007224//smoothened signaling pathway;GO:0048546//digestive tract morphogenesis;GO:0042471//ear morphogenesis;GO:0035270//endocrine system development;GO:0006260//DNA replication;GO:0034613//cellular protein localization;GO:0001656//metanephros development;GO:0060638//mesenchymal-epithelial cell signaling;GO:0050674//urothelial cell proliferation;GO:0043627//response to estrogen;GO:0042476//odontogenesis;GO:0009946//proximal/distal axis specification;GO:0040007//growth;GO:0060487//lung epithelial cell differentiation;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0019827//stem cell population maintenance;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0031657//regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0060606//tube closure;GO:0030177//positive regulation of Wnt signaling pathway;GO:0048534//hematopoietic or lymphoid organ development;GO:0030540//female genitalia development;GO:0042060//wound healing;GO:0043410//positive regulation of MAPK cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0050927//positive regulation of positive chemotaxis;GO:0032940//secretion by cell;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007265//Ras protein signal transduction;GO:0030539//male genitalia development;GO:0010631//epithelial cell migration gi|7106313|ref|NP_032028.1|/4.16061e-104/fibroblast growth factor 10 precursor [Mus musculus] 18119 2094 0.05 0.136666667 1.450661409 Up 0.194648163 Nodal nodal K04666|1|0.0|720|mmu:18119|nodal GO:0044421 GO:0070697//activin receptor binding GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0048704//embryonic skeletal system morphogenesis;GO:0007184//SMAD protein import into nucleus;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0044093;GO:0030521//androgen receptor signaling pathway;GO:0007501//mesodermal cell fate specification;GO:0022603//regulation of anatomical structure morphogenesis;GO:0030336//negative regulation of cell migration;GO:0032924//activin receptor signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0001825//blastocyst formation;GO:0001667//ameboidal-type cell migration;GO:0043410//positive regulation of MAPK cascade;GO:0010469//regulation of receptor activity;GO:0000904//cell morphogenesis involved in differentiation;GO:0003140//determination of left/right asymmetry in lateral mesoderm;GO:0001934//positive regulation of protein phosphorylation;GO:0001819//positive regulation of cytokine production;GO:0001706//endoderm formation;GO:0033504//floor plate development;GO:0060425//lung morphogenesis;GO:0008285//negative regulation of cell proliferation;GO:0007267//cell-cell signaling;GO:0007417//central nervous system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0003143//embryonic heart tube morphogenesis;GO:0001525//angiogenesis;GO:0007565//female pregnancy;GO:0009946//proximal/distal axis specification gi|218156277|ref|NP_038639.2|/0/nodal precursor [Mus musculus] 69312 1150 0.136666667 0.05 -1.450661409 Down 0.194648163 Ppp1r42 "protein phosphatase 1, regulatory subunit 42" K17579|1|2e-62|241|mmu:69312|protein phosphatase 1 regulatory subunit 42 GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0035303//regulation of dephosphorylation;GO:0035303//regulation of dephosphorylation gi|22164766|ref|NP_663730.1|/5.24935e-125/protein phosphatase 1 regulatory subunit 42 [Mus musculus] 68032 975 58.66 61 0.056432172 Up 0.194572944 Emc4 ER membrane protein complex subunit 4 - GO:0030176//integral component of endoplasmic reticulum membrane - GO:0012501//programmed cell death gi|507689725|ref|XP_004712730.1|/2.70066e-86/PREDICTED: ER membrane protein complex subunit 4 [Echinops telfairi] 100503823 2103 1.446666667 1.656666667 0.195550809 Up 0.194563541 Gm16973 "predicted gene, 16973" - - - - "gi|148704244|gb|EDL36191.1|/5.82432e-16/mCG59638, partial [Mus musculus]" 50490 3756.06 0.446666667 0.32 -0.48112669 Down 0.194563541 Nox4 NADPH oxidase 4 K08008|1|4e-105|385|tad:TRIADDRAFT_25818|NADPH oxidase GO:0031090//organelle membrane;GO:0032432//actin filament bundle;GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0044444//cytoplasmic part;GO:0005924//cell-substrate adherens junction;GO:0031090//organelle membrane;GO:0032432//actin filament bundle;GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0044444//cytoplasmic part;GO:0005924//cell-substrate adherens junction;GO:0031090//organelle membrane;GO:0032432//actin filament bundle;GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0044444//cytoplasmic part;GO:0005924//cell-substrate adherens junction "GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor;GO:0016597//amino acid binding;GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor;GO:0016597//amino acid binding;GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor;GO:0016597//amino acid binding" GO:0001894//tissue homeostasis;GO:0006915//apoptotic process;GO:0043405//regulation of MAP kinase activity;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010332//response to gamma radiation;GO:0007507//heart development;GO:0032989;GO:0001678//cellular glucose homeostasis;GO:0043410//positive regulation of MAPK cascade;GO:0007568//aging;GO:0006801//superoxide metabolic process;GO:0051591//response to cAMP;GO:0008283//cell proliferation;GO:0032233//positive regulation of actin filament bundle assembly;GO:0000096//sulfur amino acid metabolic process;GO:0071363//cellular response to growth factor stimulus;GO:0014909//smooth muscle cell migration;GO:0006950//response to stress;GO:0001894//tissue homeostasis;GO:0006915//apoptotic process;GO:0043405//regulation of MAP kinase activity;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010332//response to gamma radiation;GO:0007507//heart development;GO:0032989;GO:0001678//cellular glucose homeostasis;GO:0043410//positive regulation of MAPK cascade;GO:0007568//aging;GO:0006801//superoxide metabolic process;GO:0051591//response to cAMP;GO:0008283//cell proliferation;GO:0032233//positive regulation of actin filament bundle assembly;GO:0000096//sulfur amino acid metabolic process;GO:0071363//cellular response to growth factor stimulus;GO:0014909//smooth muscle cell migration;GO:0006950//response to stress;GO:0001894//tissue homeostasis;GO:0006915//apoptotic process;GO:0043405//regulation of MAP kinase activity;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010332//response to gamma radiation;GO:0007507//heart development;GO:0032989;GO:0001678//cellular glucose homeostasis;GO:0043410//positive regulation of MAPK cascade;GO:0007568//aging;GO:0006801//superoxide metabolic process;GO:0051591//response to cAMP;GO:0008283//cell proliferation;GO:0032233//positive regulation of actin filament bundle assembly;GO:0000096//sulfur amino acid metabolic process;GO:0071363//cellular response to growth factor stimulus;GO:0014909//smooth muscle cell migration;GO:0006950//response to stress gi|7657389|ref|NP_056575.1|/0/NADPH oxidase 4 isoform 1 [Mus musculus] 237411 2031 1.563333333 1.356666667 -0.204559128 Down 0.194563541 Zfp938 zinc finger protein 938 K09228|1|0.0|1274|mmu:237411|KRAB domain-containing zinc finger protein - - - - 56742 1739 0.34 0.473333333 0.477321778 Up 0.194563541 Psrc1 proline/serine-rich coiled-coil 1 K10129|1|3e-06|56.2|lcm:102357480|G-2 and S-phase expressed protein 1 GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0005819//spindle;GO:0044444//cytoplasmic part GO:0015631//tubulin binding;GO:0015631//tubulin binding "GO:0006351//transcription, DNA-templated;GO:0007052//mitotic spindle organization;GO:0031112;GO:0000070//mitotic sister chromatid segregation;GO:0016049//cell growth;GO:0006351//transcription, DNA-templated;GO:0007052//mitotic spindle organization;GO:0031112;GO:0000070//mitotic sister chromatid segregation;GO:0016049//cell growth" gi|9910192|ref|NP_064360.1|/1.05274e-141/proline/serine-rich coiled-coil protein 1 [Mus musculus] 69217 2678 1.386666667 1.596666667 0.203442128 Up 0.194563541 Plekha4 "pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4" K17536|1|5e-08|62.8|dre:558834|connector enhancer of kinase suppressor of Ras 2 - - - gi|568948440|ref|XP_006541221.1|/0/PREDICTED: pleckstrin homology domain-containing family A member 4 isoform X2 [Mus musculus] 14356 1013 18.22333333 17.30666667 -0.074458992 Down 0.194488322 Timm10b translocase of inner mitochondrial membrane 10B K17779|1|8e-49|196|mmu:14356|mitochondrial import inner membrane translocase subunit TIM10B GO:0019866//organelle inner membrane;GO:0005758//mitochondrial intermembrane space GO:0043169//cation binding GO:0045184//establishment of protein localization gi|9507187|ref|NP_062375.1|/6.92941e-48/mitochondrial import inner membrane translocase subunit Tim10 B [Mus musculus] 93874 3787 0.053333333 0.14 1.392317423 Up 0.194347286 Pcdhb3 protocadherin beta 3 K16494|1|0.0|1434|mmu:93874|protocadherin beta GO:0016021//integral component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion;GO:0007399//nervous system development;GO:0007267//cell-cell signaling gi|113866017|ref|NP_444358.2|/0/protocadherin beta-3 [Mus musculus] 78890 3784 0.596666667 0.456666667 -0.385783694 Down 0.194337884 Trmt44 tRNA methyltransferase 44 K15447|1|0.0|1434|mmu:78890|tRNASer (uridine44-2'-O)-methyltransferase [EC:2.1.1.211] GO:0044424 GO:0046914//transition metal ion binding;GO:0016741;GO:0097159//organic cyclic compound binding GO:0006399//tRNA metabolic process gi|254588054|ref|NP_084484.2|/0/probable tRNA (uracil-O(2)-)-methyltransferase [Mus musculus] 234023 1731 19.93666667 19.02333333 -0.067654155 Down 0.194328482 Arglu1 arginine and glutamate rich 1 K13173|1|3e-15|59.7|cge:100756104|arginine and glutamate-rich protein 1 - - - gi|625182285|ref|XP_007642049.1|/3.03862e-14/PREDICTED: arginine and glutamate-rich protein 1 isoform X1 [Cricetulus griseus] 20410 2461.69 51.22 53.52 0.063370863 Up 0.194319079 Sorbs3 sorbin and SH3 domain containing 3 K06086|1|5e-71|272|gfr:102042220|sorbin and SH3 domain containing 1 GO:0043231//intracellular membrane-bounded organelle;GO:0005924//cell-substrate adherens junction;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0005924//cell-substrate adherens junction;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0005924//cell-substrate adherens junction;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0005924//cell-substrate adherens junction;GO:0043232 GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0032233//positive regulation of actin filament bundle assembly;GO:0007155//cell adhesion;GO:0006366//transcription from RNA polymerase II promoter;GO:0000165//MAPK cascade;GO:0032233//positive regulation of actin filament bundle assembly;GO:0007155//cell adhesion;GO:0006366//transcription from RNA polymerase II promoter;GO:0000165//MAPK cascade;GO:0032233//positive regulation of actin filament bundle assembly;GO:0007155//cell adhesion;GO:0006366//transcription from RNA polymerase II promoter;GO:0000165//MAPK cascade;GO:0032233//positive regulation of actin filament bundle assembly;GO:0007155//cell adhesion;GO:0006366//transcription from RNA polymerase II promoter;GO:0000165//MAPK cascade gi|6755504|ref|NP_035496.1|/0/vinexin isoform a [Mus musculus] 68365 3100 53.60333333 51.33333333 -0.062426773 Down 0.194225055 Rab14 "RAB14, member RAS oncogene family" K07881|1|2e-119|432|fpg:101918436|Ras-related protein Rab-14 GO:0042599//lamellar body;GO:0030666//endocytic vesicle membrane;GO:0000323//lytic vacuole;GO:0005769//early endosome;GO:0005798//Golgi-associated vesicle;GO:0005783//endoplasmic reticulum;GO:0044459 GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity GO:0007275//multicellular organism development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008105//asymmetric protein localization;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0006892//post-Golgi vesicle-mediated transport;GO:0001505//regulation of neurotransmitter levels;GO:0046903//secretion;GO:0035556//intracellular signal transduction gi|909785658|ref|XP_005231254.2|/1.92653e-118/PREDICTED: ras-related protein Rab-14 isoform X1 [Falco peregrinus] 230233 6160 4.95 4.593333333 -0.107887043 Down 0.194215653 Ikbkap "inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein" K11373|1|0.0|2497|mmu:230233|elongator complex protein 1 - - - - 74411 2906 5 4.636666667 -0.108840081 Down 0.194215653 Plpp6 phospholipid phosphatase 6 K17981|1|9e-14|82.0|loa:LOAG_00360|mitochondrial fission process protein 1 - - - - 56550 2483 49.88333333 52.14666667 0.064017162 Up 0.194206251 Ube2d2a ubiquitin-conjugating enzyme E2D 2A K06689|1|7e-84|314|xtr:548818|ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0032550;GO:0019787//ubiquitin-like protein transferase activity GO:0001666//response to hypoxia;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0000209//protein polyubiquitination;GO:0019941//modification-dependent protein catabolic process "gi|829969914|ref|XP_012604220.1|/1.66063e-85/PREDICTED: ubiquitin-conjugating enzyme E2 D2, partial [Microcebus murinus]" 51886 6491 7.15 7.626666667 0.093109404 Up 0.194196848 Fubp1 far upstream element (FUSE) binding protein 1 K13210|1|0.0|823|mmu:51886|far upstream element-binding protein - - - gi|194377024|dbj|BAG63073.1|/0/unnamed protein product [Homo sapiens] 320683 6116 7.69 8.17 0.08735248 Up 0.194196848 Zfp629 zinc finger protein 629 K09228|1|0.0|695|pss:102456868|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|568950877|ref|XP_006508015.1|/0/PREDICTED: zinc finger protein 629 isoform X2 [Mus musculus] 100041979 2919 0.06 0.15 1.321928095 Up 0.194168641 Gm3604 predicted gene 3604 K09228|1|0.0|990|mmu:630579|KRAB domain-containing zinc finger protein - - - gi|242332534|ref|NP_001156382.1|/0/uncharacterized protein LOC100041979 [Mus musculus] 59069 2226.53 52.60333333 54.82 0.059548106 Up 0.194121629 Tpm3 "tropomyosin 3, gamma" K09290|1|2e-87|325|ptr:458000|tropomyosin 3 GO:0044424;GO:0043005//neuron projection;GO:0032155;GO:0005865//striated muscle thin filament;GO:0005884//actin filament;GO:0032432//actin filament bundle;GO:0032432//actin filament bundle;GO:0005865//striated muscle thin filament;GO:0032432//actin filament bundle;GO:0005865//striated muscle thin filament;GO:0043005//neuron projection;GO:0032155;GO:0005865//striated muscle thin filament;GO:0005884//actin filament;GO:0032432//actin filament bundle GO:0008092//cytoskeletal protein binding GO:0007417//central nervous system development;GO:0044763;GO:0006936//muscle contraction;GO:0044763;GO:0006936//muscle contraction;GO:0044763;GO:0006936//muscle contraction;GO:0007417//central nervous system development;GO:0044763;GO:0006936//muscle contraction gi|658132465|ref|NP_071709.3|/3.9637e-107/tropomyosin alpha-3 chain isoform Tpm3.13cy [Mus musculus] 17192 1599.99 55.10666667 57.30333333 0.0563922 Up 0.19404641 Mbd3 methyl-CpG binding domain protein 3 K11591|1|1e-151|538|rno:362834|methyl-CpG-binding domain protein 3 GO:0000785//chromatin;GO:0000118//histone deacetylase complex;GO:0000785//chromatin;GO:0000118//histone deacetylase complex GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0006366//transcription from RNA polymerase II promoter;GO:0016570//histone modification;GO:0006342//chromatin silencing;GO:0043009//chordate embryonic development;GO:0006366//transcription from RNA polymerase II promoter;GO:0016570//histone modification;GO:0006342//chromatin silencing;GO:0043009//chordate embryonic development gi|187469796|gb|AAI67041.1|/9.38892e-130/Mbd3 protein [Rattus norvegicus] 67387 1412 10.63 10.02666667 -0.084299531 Down 0.194027605 Unc50 unc-50 homolog (C. elegans) - GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0003676//nucleic acid binding GO:0045184//establishment of protein localization;GO:0007165//signal transduction "gi|148682577|gb|EDL14524.1|/1.54572e-145/unc-50 homolog (C. elegans), isoform CRA_b, partial [Mus musculus]" 246728 3873 10.64 10.04333333 -0.083259979 Down 0.194027605 Oas2 2'-5' oligoadenylate synthetase 2 K14216|1|0.0|1464|mmu:246728|2'-5'-oligoadenylate synthetase [EC:2.7.7.84] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0032550;GO:0070566//adenylyltransferase activity;GO:0003723//RNA binding GO:0051707//response to other organism;GO:0006497//protein lipidation;GO:0016070//RNA metabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0002252;GO:0006163//purine nucleotide metabolic process;GO:0006952//defense response "gi|148687808|gb|EDL19755.1|/0/2'-5' oligoadenylate synthetase 2, isoform CRA_c, partial [Mus musculus]" 386649 1486 52.41333333 54.6 0.058967088 Up 0.194027605 Nsfl1c NSFL1 (p97) cofactor (p47) K14012|1|0.0|711|cge:100763758|UBX domain-containing protein 1 GO:0044431//Golgi apparatus part;GO:0043232;GO:0044431//Golgi apparatus part;GO:0043232 GO:0032182//ubiquitin-like protein binding;GO:0008289//lipid binding;GO:0019899//enzyme binding;GO:0032182//ubiquitin-like protein binding;GO:0008289//lipid binding;GO:0019899//enzyme binding GO:0061024//membrane organization;GO:0006996//organelle organization;GO:0061024//membrane organization;GO:0006996//organelle organization "gi|148673963|gb|EDL05910.1|/0/mCG13192, isoform CRA_a, partial [Mus musculus]" 67282 1023.63 18.80333333 19.70333333 0.067451284 Up 0.194008801 Ccdc53 coiled-coil domain containing 53 K18463|1|4e-63|243|mmu:67282|WASH complex subunit CCDC53 GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - gi|171906604|ref|NP_001116432.1|/3.33592e-85/WASH complex subunit CCDC53 isoform 2 [Mus musculus] 72542 2077.34 17.92 18.82333333 0.070951493 Up 0.194008801 Pgam5 phosphoglycerate mutase family member 5 K15637|1|3e-153|545|mmu:72542|serine/threonine-protein phosphatase PGAM5 [EC:3.1.3.16] GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane GO:0016791//phosphatase activity;GO:0016791//phosphatase activity - "gi|148688083|gb|EDL20030.1|/4.36255e-161/phosphoglycerate mutase family member 5, isoform CRA_a, partial [Mus musculus]" 108160 1383 17.79666667 18.7 0.071431222 Up 0.194008801 Fam50a "family with sequence similarity 50, member A" K13119|1|9e-119|429|rno:293862|protein FAM50 GO:0043231//intracellular membrane-bounded organelle - - gi|281604125|ref|NP_001164044.1|/7.7473e-118/protein FAM50A [Rattus norvegicus] 14149 1866 5.71 5.313333333 -0.103873522 Down 0.193980593 Fdxr ferredoxin reductase K18914|1|0.0|947|mmu:14149|adrenodoxin-NADP+ reductase [EC:1.18.1.6] GO:0019866//organelle inner membrane;GO:0044429 "GO:0043168//anion binding;GO:0016731//oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor" GO:0055114//oxidation-reduction process;GO:0006091//generation of precursor metabolites and energy;GO:0016125//sterol metabolic process;GO:0051234//establishment of localization gi|74137231|dbj|BAE22000.1|/0/unnamed protein product [Mus musculus] 69694 1366 5.716666667 5.316666667 -0.104652152 Down 0.193980593 Tatdn1 TatD DNase domain containing 1 K03424|1|3e-154|547|mmu:69694|TatD DNase family protein [EC:3.1.21.-] GO:0043231//intracellular membrane-bounded organelle GO:0004520//endodeoxyribonuclease activity;GO:0043169//cation binding - "gi|148697366|gb|EDL29313.1|/2.60552e-158/TatD DNase domain containing 1, isoform CRA_b, partial [Mus musculus]" 217837 2856 5.626666667 6.023333333 0.098281602 Up 0.193980593 Itpk1 "inositol 1,3,4-triphosphate 5/6 kinase" "K00913|1|0.0|837|mmu:217837|inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase [EC:2.7.1.159 2.7.1.134]" GO:0044464 GO:0046872//metal ion binding;GO:0051766//inositol trisphosphate kinase activity;GO:0051765//inositol tetrakisphosphate kinase activity;GO:0032550 GO:0043647//inositol phosphate metabolic process gi|29789389|ref|NP_766172.1|/0/inositol-tetrakisphosphate 1-kinase [Mus musculus] 235461 8081 5.593333333 5.993333333 0.099650305 Up 0.193980593 Fam63b "family with sequence similarity 63, member B" - - - - - 380912 4229 5.59 5.986666667 0.098904661 Up 0.193980593 Zfp395 zinc finger protein 395 - - - - gi|161353467|ref|NP_950194.2|/0/zinc finger protein 395 [Mus musculus] 69162 4244 54.56 52.38 -0.058827585 Down 0.193942984 Sec31a Sec31 homolog A (S. cerevisiae) K14005|1|0.0|2268|mmu:69162|protein transport protein SEC31 GO:0030133//transport vesicle;GO:0005783//endoplasmic reticulum GO:0005515//protein binding GO:0045184//establishment of protein localization;GO:0006810//transport;GO:0010038//response to metal ion gi|244791271|ref|NP_081245.1|/0/protein transport protein Sec31A [Mus musculus] 99138 3118 51.04666667 53.22 0.060151754 Up 0.193895972 Stard7 START domain containing 7 - - - - - 75172 3389 0.476666667 0.346666667 -0.459431619 Down 0.193839558 Ccdc146 coiled-coil domain containing 146 K20478|1|1e-22|111|dre:557772|golgin subfamily B member 1 - - - gi|261245029|ref|NP_083471.1|/0/coiled-coil domain-containing protein 146 [Mus musculus] 21934 5022 0.356666667 0.49 0.458205358 Up 0.193839558 Tnfrsf11a "tumor necrosis factor receptor superfamily, member 11a, NFKB activator" K05147|1|0.0|1083|mmu:21934|tumor necrosis factor receptor superfamily member 11A GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0005515//protein binding;GO:0043169//cation binding;GO:0005035//death receptor activity GO:0031622//positive regulation of fever generation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0002573//myeloid leukocyte differentiation;GO:0006955//immune response;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0043406//positive regulation of MAP kinase activity;GO:0002237//response to molecule of bacterial origin "gi|148707924|gb|EDL39871.1|/0/tumor necrosis factor receptor superfamily, member 11a, partial [Mus musculus]" 100534273 6318 0.34 0.466666667 0.456857675 Up 0.193839558 Fer1l5 fer-1-like 5 (C. elegans) K18261|1|0.0|1353|amj:102557639|dysferlin - - - gi|459215035|ref|NP_001264005.1|/0/fer-1-like protein 5 [Mus musculus] 20130 946 57.44333333 55.28 -0.055381853 Down 0.193830155 Rras related RAS viral (r-ras) oncogene K07829|1|9e-100|365|mmu:20130|Ras-related protein R-Ras GO:0016020//membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0001525//angiogenesis;GO:0009154//purine ribonucleotide catabolic process;GO:0016477//cell migration;GO:0035556//intracellular signal transduction "gi|148690841|gb|EDL22788.1|/6.31241e-101/Harvey rat sarcoma oncogene, subgroup R, partial [Mus musculus]" 53603 1146 0.883333333 0.723333333 -0.288297317 Down 0.193792546 Tslp thymic stromal lymphopoietin K05436|1|3e-78|294|mmu:53603|thymic stromal lymphopoietin GO:0044421;GO:0044421 - - gi|10946698|ref|NP_067342.1|/2.2506e-77/thymic stromal lymphopoietin precursor [Mus musculus] 18426 2900 0.866666667 0.71 -0.287658193 Down 0.193792546 Ovol1 ovo like zinc finger 1 K09216|1|7e-160|567|mmu:18426|ovo GO:0043231//intracellular membrane-bounded organelle "GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding" "GO:0008544//epidermis development;GO:0051728;GO:1901988;GO:0044767//single-organism developmental process;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0007128//meiotic prophase I" gi|18203952|gb|AAH21411.1|/6.07091e-159/OVO homolog-like 1 (Drosophila) [Mus musculus] 30046 9977 0.71 0.87 0.293196376 Up 0.193792546 Zfp292 zinc finger protein 292 K09228|1|1e-18|100|pbi:103060232|KRAB domain-containing zinc finger protein - - - gi|169234810|ref|NP_038917.2|/0/zinc finger protein 292 [Mus musculus] 17394 2453 0.16 0.27 0.754887502 Up 0.193698522 Mmp8 matrix metallopeptidase 8 K01402|1|0.0|975|mmu:17394|matrix metalloproteinase-8 (neutrophil collagenase) [EC:3.4.24.34] GO:0044421;GO:0031012//extracellular matrix GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0019538//protein metabolic process;GO:0032963//collagen metabolic process gi|160333381|ref|NP_032637.3|/0/neutrophil collagenase preproprotein [Mus musculus] 12274 2863 0.16 0.27 0.754887502 Up 0.193698522 C6 complement component 6 K03995|1|0.0|1624|mmu:12274|complement component 6 GO:0044421;GO:0005887//integral component of plasma membrane - GO:0002699//positive regulation of immune effector process;GO:0001525//angiogenesis;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0006915//apoptotic process;GO:0001905;GO:0012502//induction of programmed cell death;GO:0006952//defense response gi|161086891|ref|NP_057913.2|/0/complement component C6 precursor [Mus musculus] 328108 6434 1.016666667 1.196666667 0.235174601 Up 0.1936139 Fam179b "family with sequence similarity 179, member B" K16578|1|2e-09|68.6|crg:105326845|CLIP-associating protein 1/2 - - - gi|254939685|ref|NP_808473.2|/0/protein FAM179B [Mus musculus] 109225 1336 1.006666667 1.19 0.241375525 Up 0.1936139 Ms4a7 "membrane-spanning 4-domains, subfamily A, member 7" - - - - "gi|148709472|gb|EDL41418.1|/1.26893e-109/membrane-spanning 4-domains, subfamily A, member 7, isoform CRA_c, partial [Mus musculus]" 57754 1657 1.28 1.48 0.209453366 Up 0.193595096 Cend1 cell cycle exit and neuronal differentiation 1 - - - GO:0008344//adult locomotory behavior;GO:0021930//cerebellar granule cell precursor proliferation;GO:0021533//cell differentiation in hindbrain;GO:0021681//cerebellar granular layer development;GO:0021932 "gi|148686123|gb|EDL18070.1|/6.15906e-51/cell cycle exit and neuronal differentiation 1, isoform CRA_b, partial [Mus musculus]" 94282 3654 1.243333333 1.44 0.211855682 Up 0.193595096 Sfxn5 sideroflexin 5 K03351|1|4e-41|173|smm:Smp_136960|anaphase-promoting complex subunit 4 GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0015142//tricarboxylic acid transmembrane transporter activity GO:0044763;GO:0006842//tricarboxylic acid transport;GO:0055080//cation homeostasis gi|30519995|ref|NP_848754.1|/5.65027e-157/sideroflexin-5 [Mus musculus] 100862203 2007 1.423333333 1.226666667 -0.214530304 Down 0.193595096 Gm6712 predicted gene 6712 K09228|1|0.0|874|mmu:22759|KRAB domain-containing zinc finger protein - - - - 108832 1448 1.28 1.48 0.209453366 Up 0.193595096 Tmem74b transmembrane protein 74B - GO:0031224//intrinsic component of membrane - - "gi|148673980|gb|EDL05927.1|/4.70741e-113/mCG50094, isoform CRA_b, partial [Mus musculus]" 268470 3974 17.31666667 18.2 0.071777202 Up 0.193576291 Ube2z ubiquitin-conjugating enzyme E2Z K10585|1|2e-151|540|pale:102880209|ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23] - - - - 18479 3081 0.603333333 0.463333333 -0.380904814 Down 0.193529279 Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 K04409|1|0.0|1001|mmu:18479|p21-activated kinase 1 [EC:2.7.11.1] GO:0043005//neuron projection;GO:0032991//macromolecular complex;GO:0031252//cell leading edge;GO:0005635//nuclear envelope;GO:0031674//I band;GO:0016020//membrane;GO:0044291//cell-cell contact zone;GO:0005924//cell-substrate adherens junction GO:0019900//kinase binding;GO:0032550;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0030520//intracellular estrogen receptor signaling pathway;GO:0032868//response to insulin;GO:0031175//neuron projection development;GO:0043406//positive regulation of MAP kinase activity;GO:0072657//protein localization to membrane;GO:0048741//skeletal muscle fiber development;GO:0008285//negative regulation of cell proliferation;GO:0032233//positive regulation of actin filament bundle assembly;GO:0016192//vesicle-mediated transport;GO:0012501//programmed cell death;GO:0009611//response to wounding;GO:0060562//epithelial tube morphogenesis gi|625259717|ref|XP_007621279.1|/0/PREDICTED: serine/threonine-protein kinase PAK 1 isoform X3 [Cricetulus griseus] 232748 4257 0.593333333 0.456666667 -0.377701348 Down 0.193529279 Tcaf2 TRPM8 channel-associated factor 2 K15259|1|1e-45|188|cmy:102945703|poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30] - - - gi|47847494|dbj|BAD21419.1|/0/mFLJ00264 protein [Mus musculus] 211548 4277 48.77333333 46.67 -0.063597107 Down 0.193482267 Nomo1 nodal modulator 1 - - - - - 102436 3881 10.39 9.8 -0.084342 Down 0.193472865 Lars2 "leucyl-tRNA synthetase, mitochondrial" K01869|1|0.0|1855|mmu:102436|leucyl-tRNA synthetase [EC:6.1.1.4] GO:0044429 GO:0032550;GO:0052689//carboxylic ester hydrolase activity;GO:0004812//aminoacyl-tRNA ligase activity GO:0006448//regulation of translational elongation;GO:0006418//tRNA aminoacylation for protein translation "gi|23346617|ref|NP_694808.1|/0/probable leucine--tRNA ligase, mitochondrial [Mus musculus]" 320661 6808 10.33 10.92 0.080132602 Up 0.193472865 D5Ertd579e "DNA segment, Chr 5, ERATO Doi 579, expressed" - - GO:0032550 - gi|485464567|ref|NP_001074701.3|/0/uncharacterized protein KIAA0232 [Mus musculus] 12339 3562 9.706666667 10.29333333 0.084662397 Up 0.193472865 Capn7 calpain 7 K08576|1|0.0|1672|mmu:12339|calpain-7 [EC:3.4.22.-] GO:0043231//intracellular membrane-bounded organelle GO:0019904//protein domain specific binding;GO:0004197//cysteine-type endopeptidase activity GO:0006508//proteolysis "gi|148692859|gb|EDL24806.1|/0/calpain 7, partial [Mus musculus]" 19060 2084 48.87 50.96 0.060416173 Up 0.193444658 Ppp5c "protein phosphatase 5, catalytic subunit" K04460|1|0.0|974|mmu:19060|serine/threonine-protein phosphatase 5 [EC:3.1.3.16] GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0042995//cell projection;GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0060089;GO:0005515//protein binding;GO:0004721//phosphoprotein phosphatase activity GO:0014072//response to isoquinoline alkaloid;GO:0051259//protein oligomerization;GO:0000087//mitotic M phase;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010467//gene expression gi|199559777|ref|NP_035285.2|/0/serine/threonine-protein phosphatase 5 [Mus musculus] 56805 4948 1.333333333 1.143333333 -0.221791424 Down 0.193388243 Zbtb33 zinc finger and BTB domain containing 33 K10507|1|0.0|1233|mmu:56805|zinc finger and BTB domain-containing protein 33 GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0007166//cell surface receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0007166//cell surface receptor signaling pathway;GO:0006351//transcription, DNA-templated" "gi|148697061|gb|EDL29008.1|/0/zinc finger and BTB domain containing 33, isoform CRA_b, partial [Mus musculus]" 232670 2015.01 1.183333333 1.376666667 0.218322757 Up 0.193388243 Tspan33 tetraspanin 33 K17346|1|5e-148|527|mmu:232670|tetraspanin-33 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|22122703|ref|NP_666285.1|/2.91664e-154/tetraspanin-33 isoform 1 [Mus musculus] 212326 5479 1.113333333 1.3 0.223626021 Up 0.193388243 Fam149a "family with sequence similarity 149, member A" - - - - gi|23956296|ref|NP_705763.1|/0/protein FAM149A [Mus musculus] 12643 1653 0.153333333 0.063333333 -1.275634443 Down 0.193350634 Chad chondroadherin K06248|1|0.0|657|mmu:12643|chondroadherin GO:0031012//extracellular matrix - - gi|6680926|ref|NP_031715.1|/0/chondroadherin precursor [Mus musculus] 72121 4048.25 0.156666667 0.063333333 -1.306661338 Down 0.193350634 Dennd2d DENN/MADD domain containing 2D K20161|1|0.0|837|mmu:72121|DENN domain-containing protein 2 - GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity - gi|74178753|dbj|BAE34027.1|/0/unnamed protein product [Mus musculus] 16452 4972 4.123333333 3.8 -0.117811676 Down 0.193322427 Jak2 Janus kinase 2 K04447|1|0.0|2272|mmu:16452|Janus kinase 2 [EC:2.7.10.2] GO:0034399//nuclear periphery;GO:0043232;GO:0044459;GO:0044444//cytoplasmic part GO:0051427//hormone receptor binding;GO:0031701//angiotensin receptor binding;GO:0035400;GO:0019900//kinase binding;GO:0046906//tetrapyrrole binding;GO:0005126//cytokine receptor binding;GO:0032550;GO:0019904//protein domain specific binding "GO:0031958;GO:0006954//inflammatory response;GO:0001775//cell activation;GO:0009636//response to toxic substance;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0010810//regulation of cell-substrate adhesion;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0007162//negative regulation of cell adhesion;GO:0032611//interleukin-1 beta production;GO:0006809//nitric oxide biosynthetic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0035406;GO:0008016//regulation of heart contraction;GO:0051100//negative regulation of binding;GO:0019221//cytokine-mediated signaling pathway;GO:0016477//cell migration;GO:0007409//axonogenesis;GO:0006979//response to oxidative stress;GO:0030099//myeloid cell differentiation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0000060//protein import into nucleus, translocation;GO:0001819//positive regulation of cytokine production;GO:0002237//response to molecule of bacterial origin;GO:0008283//cell proliferation;GO:0010922//positive regulation of phosphatase activity;GO:0051099//positive regulation of binding;GO:0050796//regulation of insulin secretion;GO:0030879//mammary gland development;GO:0043066//negative regulation of apoptotic process;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0042976//activation of Janus kinase activity" gi|114326478|ref|NP_001041642.1|/0/tyrosine-protein kinase JAK2 [Mus musculus] 230837 5582 3.893333333 3.573333333 -0.123735368 Down 0.193322427 Asap3 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 3" "K12488|1|0.0|1744|mmu:230837|Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein" GO:0044424 GO:0046914//transition metal ion binding;GO:0008289//lipid binding GO:0032012//regulation of ARF protein signal transduction "gi|56711264|ref|NP_001008233.1|/0/arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 [Mus musculus]" 72324 2901 4.12 3.803333333 -0.115379952 Down 0.193322427 Plxdc1 plexin domain containing 1 - GO:0044297//cell body;GO:0043005//neuron projection;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex - - "gi|148684158|gb|EDL16105.1|/0/plexin domain containing 1, isoform CRA_a, partial [Mus musculus]" 17158 6091 4.086666667 3.763333333 -0.118913493 Down 0.193322427 Man2a1 "mannosidase 2, alpha 1" K01231|1|0.0|2336|mmu:17158|alpha-mannosidase II [EC:3.2.1.114] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system GO:0046914//transition metal ion binding;GO:0015924//mannosyl-oligosaccharide mannosidase activity GO:0030324//lung development;GO:0006996//organelle organization;GO:0019318//hexose metabolic process;GO:0043009//chordate embryonic development;GO:0006487//protein N-linked glycosylation "gi|148706344|gb|EDL38291.1|/0/mannosidase 2, alpha 1, partial [Mus musculus]" 382056 5674 4.096666667 3.773333333 -0.118610958 Down 0.193322427 Crtc1 CREB regulated transcription coactivator 1 K15309|1|0.0|1067|mmu:382056|CREB-regulated transcription coactivator 1 GO:0031981//nuclear lumen;GO:0016020//membrane GO:0003713//transcription coactivator activity GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0051260//protein homooligomerization;GO:0006366//transcription from RNA polymerase II promoter gi|37360010|dbj|BAC97983.1|/0/mKIAA0616 protein [Mus musculus] 215445 4402.71 17.68333333 18.55333333 0.069288158 Up 0.193275415 Rab11fip3 RAB11 family interacting protein 3 (class II) K12485|1|0.0|801|mmu:215445|Rab11 family-interacting protein 3/4 - - - - 78913 7737 2.12 1.886666667 -0.168224712 Down 0.193266012 Ltn1 listerin E3 ubiquitin protein ligase 1 K01376|1|5e-47|194|smm:Smp_179040|UFM1-specific protease 2 [EC:3.4.22.-];K01758|3|2e-29|135|aqu:100634864|cystathionine gamma-lyase [EC:4.4.1.1] - - - gi|50510603|dbj|BAD32287.1|/0/mKIAA0714 protein [Mus musculus] 12493 1226 1.846666667 2.073333333 0.167028604 Up 0.193266012 Cd37 CD37 antigen K06475|1|6e-127|456|mmu:12493|CD37 antigen GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane - GO:0001562//response to protozoan;GO:0006959//humoral immune response;GO:0002697;GO:0008283//cell proliferation;GO:0002377//immunoglobulin production;GO:0001773//myeloid dendritic cell activation;GO:0001562//response to protozoan;GO:0006959//humoral immune response;GO:0002697;GO:0008283//cell proliferation;GO:0002377//immunoglobulin production;GO:0001773//myeloid dendritic cell activation;GO:0001562//response to protozoan;GO:0006959//humoral immune response;GO:0002697;GO:0008283//cell proliferation;GO:0002377//immunoglobulin production;GO:0001773//myeloid dendritic cell activation gi|595763170|ref|NP_001277731.1|/8.53338e-126/leukocyte antigen CD37 isoform 1 [Mus musculus] 72502 3581 1.85 2.076666667 0.166744392 Up 0.193266012 Cwf19l1 "CWF19-like 1, cell cycle control (S. pombe)" K04467|1|3e-179|632|fpg:101914413|inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10];K18328|3|3e-12|77.4|xma:102230283|lariat debranching enzyme [EC:3.1.-.-] - - - gi|124487291|ref|NP_001074546.1|/0/CWF19-like protein 1 [Mus musculus] 216119 4538 1.91 2.143333333 0.166283599 Up 0.193266012 Ybey ybeY metallopeptidase K03691|1|9e-38|162|fab:101806242|peptide-O-fucosyltransferase [EC:2.4.1.221] GO:0043231//intracellular membrane-bounded organelle GO:0004175//endopeptidase activity;GO:0043169//cation binding GO:0019538//protein metabolic process gi|148699903|gb|EDL31850.1|/3.7589e-81/RIKEN cDNA A130042E20 [Mus musculus] 26874 5540 2.03 1.803333333 -0.170813634 Down 0.193266012 Abcd2 "ATP-binding cassette, sub-family D (ALD), member 2" "K05676|1|0.0|1450|mmu:26874|ATP-binding cassette, subfamily D (ALD), member 2" GO:0031224//intrinsic component of membrane;GO:0044439 GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0042802//identical protein binding GO:0000038//very long-chain fatty acid metabolic process;GO:0044763;GO:0006635//fatty acid beta-oxidation;GO:0051234//establishment of localization gi|60218875|ref|NP_036124.2|/0/ATP-binding cassette sub-family D member 2 [Mus musculus] 224742 3207 46.81666667 44.77666667 -0.064275086 Down 0.19325661 Abcf1 "ATP-binding cassette, sub-family F (GCN20), member 1" "K06184|1|0.0|1157|mmu:224742|ATP-binding cassette, subfamily F, member 1" GO:0005840//ribosome;GO:0031981//nuclear lumen;GO:0012505//endomembrane system "GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0043021//ribonucleoprotein complex binding;GO:0090079//translation regulator activity, nucleic acid binding" GO:0006412//translation;GO:0022613//ribonucleoprotein complex biogenesis gi|39930335|ref|NP_038882.1|/0/ATP-binding cassette sub-family F member 1 [Mus musculus] 18542 1539 46.22333333 48.25 0.061907641 Up 0.193219 Pcolce procollagen C-endopeptidase enhancer protein K05502|1|3e-45|185|xla:397872|bone morphogenetic protein 1 [EC:3.4.24.19] GO:0031988//membrane-bounded vesicle;GO:0005578//proteinaceous extracellular matrix GO:0008047//enzyme activator activity;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding GO:0019538//protein metabolic process;GO:0051345//positive regulation of hydrolase activity gi|125490382|ref|NP_032814.2|/0/procollagen C-endopeptidase enhancer 1 precursor [Mus musculus] 69964 1005 0.25 0.37 0.565597176 Up 0.193200196 2810403D21Rik RIKEN cDNA 2810403D21 gene - - - - - 16589 2041 0.246666667 0.366666667 0.571906348 Up 0.193200196 Uhmk1 U2AF homology motif (UHM) kinase 1 K08877|1|0.0|751|mmu:16589|U2AF homology motif (UHM) kinase 1 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0030425//dendrite GO:0032550;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0003676//nucleic acid binding GO:0006413//translational initiation;GO:0006611//protein export from nucleus;GO:0030030//cell projection organization;GO:0006468//protein phosphorylation;GO:0022402//cell cycle process gi|640826224|ref|XP_008070255.1|/0/PREDICTED: serine/threonine-protein kinase Kist [Tarsius syrichta] 210293 7308 0.383333333 0.26 -0.560087832 Down 0.193162586 Dock10 dedicator of cytokinesis 10 K05727|1|1e-11|76.6|amj:102570974|dedicator of cytokinesis protein 3 - - - gi|553726991|ref|NP_001272856.1|/0/dedicator of cytokinesis protein 10 isoform 2 [Mus musculus] 12334 3205 48.75333333 46.77666667 -0.059711803 Down 0.192993343 Capn2 calpain 2 K03853|1|0.0|1362|mmu:12334|calpain-2 [EC:3.4.22.53] GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0016020//membrane GO:0046872//metal ion binding;GO:0004197//cysteine-type endopeptidase activity;GO:0046983//protein dimerization activity GO:0000768//syncytium formation by plasma membrane fusion;GO:0016485//protein processing;GO:0001701//in utero embryonic development;GO:0006950//response to stress gi|74191860|dbj|BAE32880.1|/0/unnamed protein product [Mus musculus] 216028 3852 0.163333333 0.07 -1.222392421 Down 0.192974538 Lrrtm3 leucine rich repeat transmembrane neuronal 3 K16665|1|6e-133|478|cmk:103190462|leucine-rich repeat transmembrane neuronal protein 1/2 - - - - 69187 953 0.063333333 0.15 1.243925583 Up 0.192974538 Erp27 endoplasmic reticulum protein 27 K20355|1|3e-143|509|mmu:69187|endoplasmic reticulum protein 27 GO:0005783//endoplasmic reticulum - - gi|21746145|ref|NP_081259.1|/2.56238e-142/endoplasmic reticulum resident protein 27 precursor [Mus musculus] 100302648 869 0.066666667 0.156666667 1.232660757 Up 0.192974538 Gm11944 predicted gene 11944 - - - - - 14709 920 0.063333333 0.15 1.243925583 Up 0.192974538 Gng8 "guanine nucleotide binding protein (G protein), gamma 8" K04544|1|5e-31|137|ocu:100355417|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 - - - gi|291413312|ref|XP_002722922.1|/4.23281e-30/PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 isoform X1 [Oryctolagus cuniculus] 18053 3409 0.066666667 0.156666667 1.232660757 Up 0.192974538 Ngfr "nerve growth factor receptor (TNFR superfamily, member 16)" K02583|1|0.0|803|mmu:18053|nerve growth factor receptor (TNFR superfamily member 16) GO:0009986//cell surface;GO:0030139//endocytic vesicle;GO:0031224//intrinsic component of membrane;GO:0032589//neuron projection membrane;GO:0005783//endoplasmic reticulum;GO:0012505//endomembrane system;GO:0043025//neuronal cell body GO:0043121//neurotrophin binding;GO:0004888//transmembrane signaling receptor activity;GO:0005167;GO:0017016//Ras GTPase binding;GO:0044389//ubiquitin-like protein ligase binding "GO:0010467//gene expression;GO:0008284//positive regulation of cell proliferation;GO:0031641//regulation of myelination;GO:0042475//odontogenesis of dentin-containing tooth;GO:0015031//protein transport;GO:0001942//hair follicle development;GO:0009266//response to temperature stimulus;GO:0035249//synaptic transmission, glutamatergic;GO:0007271//synaptic transmission, cholinergic;GO:0007600//sensory perception;GO:0012502//induction of programmed cell death;GO:0006979//response to oxidative stress;GO:0032845;GO:0006935//chemotaxis;GO:0010975//regulation of neuron projection development;GO:0031323//regulation of cellular metabolic process;GO:0033500//carbohydrate homeostasis;GO:0046324//regulation of glucose import;GO:0002237//response to molecule of bacterial origin;GO:0007266//Rho protein signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0000165//MAPK cascade;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007519//skeletal muscle tissue development" gi|70794803|ref|NP_150086.2|/0/tumor necrosis factor receptor superfamily member 16 precursor [Mus musculus] 114872 5441 0.07 0.163333333 1.222392421 Up 0.192974538 Psg29 pregnancy-specific glycoprotein 29 K06499|1|3e-114|416|cge:100752782|carcinoembryonic antigen-related cell adhesion molecule - - GO:0044703 gi|74959908|ref|NP_473405.1|/0/pregnancy-specific glycoprotein 29 [Mus musculus] 230676 10958 3.44 3.15 -0.127056736 Down 0.192946331 Szt2 seizure threshold 2 - GO:0042579//microbody - GO:0007399//nervous system development gi|253314408|ref|NP_937813.3|/0/protein SZT2 [Mus musculus] 217431 3004 3.106666667 3.396666667 0.128752192 Up 0.192946331 Nol10 nucleolar protein 10 K14788|1|0.0|1162|mmu:217431|ribosome biogenesis protein ENP2 GO:0031981//nuclear lumen - - gi|56606027|ref|NP_001008421.1|/0/nucleolar protein 10 [Mus musculus] 109934 4874.77 10.32333333 10.90333333 0.078860376 Up 0.192889917 Abr active BCR-related gene K08878|1|0.0|1623|mdo:100011712|breakpoint cluster region protein [EC:2.7.11.1] GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044444//cytoplasmic part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding GO:0007010//cytoskeleton organization;GO:0006909//phagocytosis;GO:0007266//Rho protein signal transduction;GO:0007417//central nervous system development;GO:0002695//negative regulation of leukocyte activation;GO:0042471//ear morphogenesis;GO:0006954//inflammatory response;GO:0002237//response to molecule of bacterial origin;GO:0016477//cell migration;GO:0050905//neuromuscular process;GO:0007010//cytoskeleton organization;GO:0006909//phagocytosis;GO:0007266//Rho protein signal transduction;GO:0007417//central nervous system development;GO:0012501//programmed cell death;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0002695//negative regulation of leukocyte activation;GO:0042471//ear morphogenesis;GO:0006954//inflammatory response;GO:0002237//response to molecule of bacterial origin;GO:0016477//cell migration;GO:0050905//neuromuscular process;GO:0007010//cytoskeleton organization;GO:0006909//phagocytosis;GO:0007266//Rho protein signal transduction;GO:0007417//central nervous system development;GO:0002695//negative regulation of leukocyte activation;GO:0042471//ear morphogenesis;GO:0006954//inflammatory response;GO:0002237//response to molecule of bacterial origin;GO:0016477//cell migration;GO:0050905//neuromuscular process gi|37574113|ref|NP_932135.1|/0/active breakpoint cluster region-related protein isoform 1 [Mus musculus] 101497 5067 10.43 11.00666667 0.077638462 Up 0.192889917 Plekhg2 "pleckstrin homology domain containing, family G (with RhoGef domain) member 2" "K05769|1|1e-22|112|nve:NEMVE_v1g92887|Rho guanine nucleotide exchange factor 4;K05731|2|2e-21|108|xma:102238061|T-lymphoma invasion and metastasis-inducing protein 1;K12365|3|2e-21|108|oas:101115893|phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein" GO:0044464;GO:0044464;GO:0044464 GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction gi|47847376|dbj|BAD21360.1|/0/mFLJ00018 protein [Mus musculus] 24064 2103 9.61 10.19 0.084545715 Up 0.192889917 Spry2 sprouty homolog 2 (Drosophila) K17383|1|1e-168|595|mmu:24064|protein sprouty homolog 2 GO:0044444//cytoplasmic part;GO:0001726//ruffle;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane GO:0019900//kinase binding;GO:0004860//protein kinase inhibitor activity;GO:0030295//protein kinase activator activity GO:0010467//gene expression;GO:0006915//apoptotic process;GO:0043405//regulation of MAP kinase activity;GO:0043409//negative regulation of MAPK cascade;GO:0050954//sensory perception of mechanical stimulus;GO:0042471//ear morphogenesis;GO:0034260//negative regulation of GTPase activity;GO:0043410//positive regulation of MAPK cascade;GO:0001933//negative regulation of protein phosphorylation;GO:0007265//Ras protein signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0030154//cell differentiation;GO:0008283//cell proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045860//positive regulation of protein kinase activity;GO:0030324//lung development;GO:0060562//epithelial tube morphogenesis gi|6755652|ref|NP_036027.1|/1.08784e-167/protein sprouty homolog 2 [Mus musculus] 84095 3771 10.98 10.4 -0.078294526 Down 0.192889917 Pi4k2a phosphatidylinositol 4-kinase type 2 alpha K13711|1|0.0|865|mmu:84095|phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67] GO:0030427//site of polarized growth;GO:0043005//neuron projection;GO:0030133//transport vesicle;GO:0097060//synaptic membrane;GO:0033644//host cell membrane;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body;GO:0005769//early endosome;GO:0008021//synaptic vesicle;GO:0031082 GO:0032550;GO:0046872//metal ion binding;GO:0052742;GO:0032403//protein complex binding GO:0046474//glycerophospholipid biosynthetic process;GO:0046488//phosphatidylinositol metabolic process;GO:0002276 gi|21703986|ref|NP_663476.1|/0/phosphatidylinositol 4-kinase type 2-alpha [Mus musculus] 66196 3924 2.306666667 2.07 -0.156178769 Down 0.192833503 Myo19 myosin XIX K10357|1|7e-124|448|lgi:LOTGIDRAFT_122399|myosin V GO:0015629//actin cytoskeleton;GO:0031966//mitochondrial membrane GO:0008092//cytoskeletal protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 - gi|254939539|ref|NP_079690.2|/0/unconventional myosin-XIX [Mus musculus] 56532 1882 2.033333333 2.27 0.158845556 Up 0.192833503 Ripk3 receptor-interacting serine-threonine kinase 3 K08847|1|0.0|783|mmu:56532|receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1] GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0005515//protein binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0005515//protein binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0005515//protein binding GO:0010940//positive regulation of necrotic cell death;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0051259//protein oligomerization;GO:0012502//induction of programmed cell death;GO:0045860//positive regulation of protein kinase activity;GO:0072593//reactive oxygen species metabolic process;GO:0010940//positive regulation of necrotic cell death;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0051259//protein oligomerization;GO:0012502//induction of programmed cell death;GO:0045860//positive regulation of protein kinase activity;GO:0072593//reactive oxygen species metabolic process;GO:0010940//positive regulation of necrotic cell death;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0051259//protein oligomerization;GO:0012502//induction of programmed cell death;GO:0045860//positive regulation of protein kinase activity;GO:0072593//reactive oxygen species metabolic process gi|256017133|ref|NP_064339.2|/0/receptor-interacting serine/threonine-protein kinase 3 isoform 1 [Mus musculus] 16170 4989 2.306666667 2.07 -0.156178769 Down 0.192833503 Il16 interleukin 16 K16220|1|3e-27|127|asn:102371674|HCLS1-associated protein X-1;K06095|3|5e-18|97.1|tru:101078693|multiple PDZ domain protein GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0044421 GO:0005102//receptor binding "GO:0050927//positive regulation of positive chemotaxis;GO:0050900//leukocyte migration;GO:0006351//transcription, DNA-templated" gi|60360480|dbj|BAD90484.1|/0/mKIAA4048 protein [Mus musculus] 14457 6921.24 2.273333333 2.033333333 -0.160962497 Down 0.192833503 Gas7 growth arrest specific 7 K18618|1|0.0|716|rno:85246|growth arrest-specific protein 7 GO:0031252//cell leading edge;GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton;GO:0015629//actin cytoskeleton GO:0003779//actin binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003779//actin binding;GO:0003779//actin binding;GO:0003779//actin binding "GO:0022604//regulation of cell morphogenesis;GO:0031175//neuron projection development;GO:0008154//actin polymerization or depolymerization;GO:0022402//cell cycle process;GO:0022604//regulation of cell morphogenesis;GO:0031175//neuron projection development;GO:0008154//actin polymerization or depolymerization;GO:0006351//transcription, DNA-templated;GO:0022604//regulation of cell morphogenesis;GO:0031175//neuron projection development;GO:0008154//actin polymerization or depolymerization;GO:0022604//regulation of cell morphogenesis;GO:0031175//neuron projection development;GO:0008154//actin polymerization or depolymerization" gi|12643779|sp|Q60780.1|GAS7_MOUSE/0/RecName: Full=Growth arrest-specific protein 7; Short=GAS-7 66136 686 16.49333333 17.34666667 0.072775462 Up 0.192814698 Znrd1 "zinc ribbon domain containing, 1" K03000|1|5e-69|262|mmu:66136|DNA-directed RNA polymerase I subunit RPA12 GO:0031981//nuclear lumen GO:0034062//RNA polymerase activity;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0010467//gene expression gi|12963545|ref|NP_075651.1|/3.72345e-68/DNA-directed RNA polymerase I subunit RPA12 [Mus musculus] 56809 6518 2.516666667 2.27 -0.148821846 Down 0.192777088 Gmeb1 glucocorticoid modulatory element binding protein 1 "K03847|1|7e-10|70.5|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0043169//cation binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0043169//cation binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148698170|gb|EDL30117.1|/0/glucocorticoid modulatory element binding protein 1, isoform CRA_b, partial [Mus musculus]" 104082 7109 2.46 2.213333333 -0.152437575 Down 0.192777088 Wdr7 WD repeat domain 7 K12862|1|4e-08|64.7|cbr:CBG09714|pleiotropic regulator 1;K04508|4|7e-07|60.5|loa:LOAG_03965|transducin (beta)-like 1 - - - gi|226494598|ref|NP_001014981.1|/0/WD repeat-containing protein 7 [Mus musculus] 26430 4391 2.43 2.183333333 -0.154423908 Down 0.192777088 Parg poly (ADP-ribose) glycohydrolase K07759|1|0.0|1877|mmu:26430|poly(ADP-ribose) glycohydrolase [EC:3.2.1.143] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part "GO:0005488//binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds" GO:0006281//DNA repair;GO:0009581 gi|55735518|sp|O88622.2|PARG_MOUSE/0/RecName: Full=Poly(ADP-ribose) glycohydrolase 23888 6750 2.49 2.243333333 -0.150501738 Down 0.192777088 Gpc6 glypican 6 K08112|1|0.0|1011|mmu:23888|glypican 6 GO:0031012//extracellular matrix;GO:0016021//integral component of membrane;GO:0005764//lysosome;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0044431//Golgi apparatus part;GO:0044421 GO:0043168//anion binding;GO:0043168//anion binding GO:0048870//cell motility;GO:0044238//primary metabolic process;GO:0048870//cell motility;GO:0006026;GO:0006790//sulfur compound metabolic process;GO:0006023 gi|7106325|ref|NP_035951.1|/0/glypican-6 isoform 2 precursor [Mus musculus] 66962 1846 4.206666667 4.553333333 0.114245573 Up 0.192711272 Swsap1 SWIM type zinc finger 7 associated protein 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0017111//nucleoside-triphosphatase activity;GO:0043566//structure-specific DNA binding GO:0009154//purine ribonucleotide catabolic process;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0031647//regulation of protein stability gi|244791057|ref|NP_080146.1|/6.07651e-119/ATPase SWSAP1 [Mus musculus] 245828 745 45.11333333 47.04666667 0.060538621 Up 0.192711272 Trappc1 trafficking protein particle complex 1 K20300|1|2e-80|300|rno:287427|trafficking protein particle complex subunit 1 GO:0005801//cis-Golgi network - GO:0016482//cytosolic transport gi|880871034|ref|XP_005067617.2|/4.61315e-89/PREDICTED: trafficking protein particle complex subunit 1 [Mesocricetus auratus] 12354 1650.19 4.466666667 4.82 0.109834552 Up 0.192711272 Car7 carbonic anhydrase 7 K01672|1|3e-157|557|mmu:12354|carbonic anhydrase [EC:4.2.1.1] GO:0044424;GO:0044424;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0016836//hydro-lyase activity GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0044237//cellular metabolic process;GO:0015711//organic anion transport;GO:0044710 gi|589931512|ref|XP_006978559.1|/1.26016e-148/PREDICTED: carbonic anhydrase 7 isoform X1 [Peromyscus maniculatus bairdii] 77252 1125 4.58 4.233333333 -0.113553507 Down 0.192711272 9430038I01Rik RIKEN cDNA 9430038I01 gene K04828|1|6e-06|54.3|lve:103085748|acid-sensing ion channel 2 - - - gi|242397485|ref|NP_084162.1|/6.71054e-58/uncharacterized protein LOC77252 [Mus musculus] 17250 5959 6.016666667 5.623333333 -0.097538863 Down 0.192701869 Abcc1 "ATP-binding cassette, sub-family C (CFTR/MRP), member 1" "K05665|1|0.0|2926|mmu:17250|ATP-binding cassette, subfamily C (CFTR/MRP), member 1" GO:0031981//nuclear lumen;GO:0016021//integral component of membrane;GO:0044459 GO:0042887;GO:0032550;GO:0071997;GO:0015245//fatty acid transporter activity GO:0060548//negative regulation of cell death;GO:0015695//organic cation transport;GO:0015909//long-chain fatty acid transport;GO:0015893//drug transport;GO:0015914//phospholipid transport;GO:0003333//amino acid transmembrane transport;GO:0006935//chemotaxis;GO:0009154//purine ribonucleotide catabolic process;GO:0006950//response to stress;GO:0016477//cell migration gi|6678848|ref|NP_032602.1|/0/multidrug resistance-associated protein 1 [Mus musculus] 70791 3146 5.69 6.083333333 0.096433406 Up 0.192701869 Hars2 histidyl-tRNA synthetase 2 K01892|1|0.0|968|mmu:70791|histidyl-tRNA synthetase [EC:6.1.1.21] - - - - 319554 2883 1.6 1.816666667 0.183221824 Up 0.192645455 Idi1 isopentenyl-diphosphate delta isomerase K01823|1|8e-164|580|mmu:319554|isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2] GO:0042579//microbody "GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds;GO:0046914//transition metal ion binding" GO:0006720//isoprenoid metabolic process;GO:0080184//response to phenylpropanoid;GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0008654//phospholipid biosynthetic process gi|281604088|ref|NP_663335.2|/6.87884e-163/isopentenyl-diphosphate Delta-isomerase 1 [Mus musculus] 75540 3526 1.89 1.673333333 -0.175661371 Down 0.192645455 Fpgt fucose-1-phosphate guanylyltransferase K00976|1|0.0|1157|mmu:75540|fucose-1-phosphate guanylyltransferase [EC:2.7.7.30] - GO:0070568 GO:0009226//nucleotide-sugar biosynthetic process gi|117676389|ref|NP_083606.2|/0/fucose-1-phosphate guanylyltransferase [Mus musculus] 58233 3005 48.26333333 46.36333333 -0.057943266 Down 0.192542029 Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 K09505|1|0.0|719|mmu:58233|DnaJ homolog subfamily A member 4 - - - - 78283 2991.88 0.506666667 0.373333333 -0.440572591 Down 0.192532626 Map7d2 MAP7 domain containing 2 K16807|1|3e-14|84.0|cmk:103178112|MAP7 domain-containing protein 3 - - - - 72155 1768 0.76 0.923333333 0.280852152 Up 0.192532626 Cenpn centromere protein N K11506|1|0.0|679|mmu:72155|centromere protein N "GO:0000775//chromosome, centromeric region;GO:0043231//intracellular membrane-bounded organelle" - - gi|21312392|ref|NP_082407.1|/0/centromere protein N [Mus musculus] 170826 3656 7.413333333 6.953333333 -0.09241763 Down 0.192485614 Ppargc1b "peroxisome proliferative activated receptor, gamma, coactivator 1 beta" K17962|1|0.0|1711|mmu:170826|peroxisome proliferator-activated receptor gamma coactivator 1-beta GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0003713//transcription coactivator activity;GO:0035258//steroid hormone receptor binding;GO:0036094//small molecule binding;GO:0030545" GO:0032846;GO:0010692;GO:0006366//transcription from RNA polymerase II promoter;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0046683//response to organophosphorus;GO:0016310//phosphorylation;GO:0000302//response to reactive oxygen species;GO:0030036//actin cytoskeleton organization;GO:0010469//regulation of receptor activity;GO:0031960//response to corticosteroid;GO:0048705//skeletal system morphogenesis;GO:0000959//mitochondrial RNA metabolic process;GO:0030518//intracellular steroid hormone receptor signaling pathway gi|18875426|ref|NP_573512.1|/0/peroxisome proliferator-activated receptor gamma coactivator 1-beta [Mus musculus] 68558 1795.59 7.576666667 7.12 -0.089686037 Down 0.192485614 Ankra2 "ankyrin repeat, family A (RFXANK-like), 2" K08062|1|5e-63|244|tup:102498441|regulatory factor X-associated ankyrin-containing protein GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0071813//lipoprotein particle binding;GO:0019899//enzyme binding;GO:0071813//lipoprotein particle binding;GO:0019899//enzyme binding;GO:0071813//lipoprotein particle binding;GO:0019899//enzyme binding;GO:0071813//lipoprotein particle binding;GO:0019899//enzyme binding;GO:0071813//lipoprotein particle binding;GO:0019899//enzyme binding;GO:0071813//lipoprotein particle binding;GO:0019899//enzyme binding - "gi|148668539|gb|EDL00858.1|/5.32653e-164/ankyrin repeat, family A (RFXANK-like), 2, isoform CRA_e, partial [Mus musculus]" 67830 1518 46.43 48.32 0.057563174 Up 0.192457407 Rer1 retention in endoplasmic reticulum sorting receptor 1 - GO:0031228//intrinsic component of Golgi membrane - GO:0048193//Golgi vesicle transport gi|530598602|ref|XP_005292812.1|/1.12049e-112/PREDICTED: protein RER1 isoform X1 [Chrysemys picta bellii] 74012 4197 1.44 1.646666667 0.193479729 Up 0.192382188 Rap2b "RAP2B, member of RAS oncogene family" K07838|1|4e-90|336|pale:102893970|Ras-related protein Rap-2B GO:0010008//endosome membrane GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity GO:0001934//positive regulation of protein phosphorylation;GO:0007265//Ras protein signal transduction;GO:0045859//regulation of protein kinase activity;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0030036//actin cytoskeleton organization;GO:0007254//JNK cascade;GO:0008104//protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0016477//cell migration gi|13386338|ref|NP_082988.1|/3.44725e-89/ras-related protein Rap-2b precursor [Mus musculus] 330409 9213 1.433333333 1.64 0.194321656 Up 0.192382188 Cecr2 "cat eye syndrome chromosome region, candidate 2" K06062|1|8e-19|100|ola:101159205|histone acetyltransferase [EC:2.3.1.48] - - - gi|189458854|ref|NP_001121623.1|/0/cat eye syndrome critical region protein 2 [Mus musculus] 320538 14671 1.556666667 1.77 0.185289311 Up 0.192382188 Ubn2 ubinuclein 2 K17492|1|0.0|1821|mmu:320538|ubinuclein - - - - 14205 1762.18 1.456666667 1.666666667 0.194294815 Up 0.192382188 Figf vascular endothelial growth factor D K05449|1|0.0|746|mmu:14205|vascular endothelial growth factor C/D GO:0031091//platelet alpha granule;GO:0044421;GO:0044421 GO:0005172//vascular endothelial growth factor receptor binding;GO:0042802//identical protein binding;GO:0042802//identical protein binding;GO:0005172//vascular endothelial growth factor receptor binding GO:0007599//hemostasis;GO:0050927//positive regulation of positive chemotaxis;GO:0008283//cell proliferation;GO:0006887//exocytosis;GO:0002551//mast cell chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0048522;GO:0009966//regulation of signal transduction;GO:0048869//cellular developmental process;GO:0001775//cell activation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048869//cellular developmental process;GO:0001525//angiogenesis;GO:0002551//mast cell chemotaxis;GO:0001819//positive regulation of cytokine production;GO:0050927//positive regulation of positive chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048522;GO:0009966//regulation of signal transduction;GO:0034097//response to cytokine;GO:0008283//cell proliferation;GO:0006950//response to stress gi|819231786|ref|NP_001295418.1|/0/vascular endothelial growth factor D isoform VEGF-D326 preproprotein [Mus musculus] 271564 11178 1.73 1.516666667 -0.189867993 Down 0.192382188 Vps13a vacuolar protein sorting 13A K19525|1|0.0|5992|mmu:271564|vacuolar protein sorting-associated protein 13A/C GO:0030141//secretory granule - GO:0051705;GO:0048731//system development;GO:0044708//single-organism behavior;GO:0045184//establishment of protein localization gi|66392160|ref|NP_766616.2|/0/vacuolar protein sorting-associated protein 13A [Mus musculus] 217337 2546 45 46.87666667 0.058944984 Up 0.192363383 Srp68 signal recognition particle 68 K03107|1|0.0|1132|mmu:217337|signal recognition particle subunit SRP68 GO:0048500//signal recognition particle;GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0005048//signal sequence binding;GO:0043021//ribonucleoprotein complex binding GO:0019538//protein metabolic process;GO:0042221//response to chemical;GO:0006613//cotranslational protein targeting to membrane;GO:0010467//gene expression gi|47271535|ref|NP_666144.3|/0/signal recognition particle subunit SRP68 [Mus musculus] 14463 3405.88 42.84666667 44.72 0.061737217 Up 0.192344579 Gata4 GATA binding protein 4 K09183|1|2e-169|599|mmu:14463|GATA-binding protein 4 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0008134//transcription factor binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0046914//transition metal ion binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0046332//SMAD binding;GO:0008134//transcription factor binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0046914//transition metal ion binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0046332//SMAD binding" GO:0032970//regulation of actin filament-based process;GO:0001704//formation of primary germ layer;GO:0002065;GO:0006914//autophagy;GO:0016055//Wnt signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0003285//septum secundum development;GO:0009952//anterior/posterior pattern specification;GO:0043009//chordate embryonic development;GO:0048232//male gamete generation;GO:0003299;GO:0001678//cellular glucose homeostasis;GO:0035051//cardiocyte differentiation;GO:0032870//cellular response to hormone stimulus;GO:0030509//BMP signaling pathway;GO:0003301//physiological cardiac muscle hypertrophy;GO:0003171//atrioventricular valve development;GO:0009605//response to external stimulus;GO:0001819//positive regulation of cytokine production;GO:0007599//hemostasis;GO:0003209//cardiac atrium morphogenesis;GO:0001570//vasculogenesis;GO:0003284//septum primum development;GO:0048545//response to steroid hormone;GO:0003143//embryonic heart tube morphogenesis;GO:0003183//mitral valve morphogenesis;GO:0001525//angiogenesis;GO:0008584//male gonad development;GO:0007440//foregut morphogenesis;GO:0032354//response to follicle-stimulating hormone;GO:0048644//muscle organ morphogenesis;GO:0003208//cardiac ventricle morphogenesis;GO:0003186//tricuspid valve morphogenesis;GO:0032970//regulation of actin filament-based process;GO:0001704//formation of primary germ layer;GO:0002065;GO:0006914//autophagy;GO:0016055//Wnt signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0003285//septum secundum development;GO:0009952//anterior/posterior pattern specification;GO:0043009//chordate embryonic development;GO:0048232//male gamete generation;GO:0003299;GO:0001678//cellular glucose homeostasis;GO:0035051//cardiocyte differentiation;GO:0032870//cellular response to hormone stimulus;GO:0030509//BMP signaling pathway;GO:0003301//physiological cardiac muscle hypertrophy;GO:0003171//atrioventricular valve development;GO:0009605//response to external stimulus;GO:0001819//positive regulation of cytokine production;GO:0007599//hemostasis;GO:0003209//cardiac atrium morphogenesis;GO:0001570//vasculogenesis;GO:0003284//septum primum development;GO:0048545//response to steroid hormone;GO:0003143//embryonic heart tube morphogenesis;GO:0003183//mitral valve morphogenesis;GO:0001525//angiogenesis;GO:0008584//male gonad development;GO:0007440//foregut morphogenesis;GO:0032354//response to follicle-stimulating hormone;GO:0048644//muscle organ morphogenesis;GO:0003208//cardiac ventricle morphogenesis;GO:0003186//tricuspid valve morphogenesis gi|890790730|ref|NP_001297539.1|/5.96703e-169/transcription factor GATA-4 isoform 1 [Mus musculus] 230500 2132 0.166666667 0.276666667 0.731183242 Up 0.192278762 Efcab7 EF-hand calcium binding domain 7 K02183|1|6e-12|75.5|crg:105319979|calmodulin - GO:0043169//cation binding - gi|74209159|dbj|BAE24969.1|/0/unnamed protein product [Mus musculus] 13041 1438 0.176666667 0.29 0.715023041 Up 0.192278762 Ctsw cathepsin W K08569|1|0.0|778|mmu:13041|cathepsin W [EC:3.4.22.-] - - - - 15466 2789 0.163333333 0.27 0.725140159 Up 0.192278762 Hrh2 histamine receptor H2 K04150|1|0.0|733|mmu:15466|histamine receptor H2 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0008227//G-protein coupled amine receptor activity;GO:0008227//G-protein coupled amine receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007611//learning or memory;GO:0007632//visual behavior;GO:0001696//gastric acid secretion;GO:0019229//regulation of vasoconstriction;GO:0046058//cAMP metabolic process;GO:0000904//cell morphogenesis involved in differentiation;GO:0050804//modulation of synaptic transmission;GO:0007166//cell surface receptor signaling pathway;GO:0007611//learning or memory;GO:0007632//visual behavior;GO:0001696//gastric acid secretion;GO:0019229//regulation of vasoconstriction;GO:0046058//cAMP metabolic process;GO:0000904//cell morphogenesis involved in differentiation;GO:0050804//modulation of synaptic transmission gi|58331134|ref|NP_001010973.1|/0/histamine H2 receptor isoform 1 [Mus musculus] 77117 2182.01 0.27 0.163333333 -0.725140159 Down 0.192278762 Zfp934 zinc finger protein 934 K09228|1|0.0|820|mmu:630579|KRAB domain-containing zinc finger protein - - - gi|110815832|ref|NP_001034328.2|/0/zinc finger protein 80 [Mus musculus] 226025 4267.15 0.29 0.176666667 -0.715023041 Down 0.192278762 Trpm3 "transient receptor potential cation channel, subfamily M, member 3" K04978|1|0.0|2472|cfr:102508432|transient receptor potential cation channel subfamily M member 3 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport;GO:0006811//ion transport gi|78214526|ref|NP_001030316.1|/0/transient receptor potential cation channel subfamily M member 3 isoform a [Mus musculus] 66522 4882 9.456666667 10.02666667 0.084438416 Up 0.192259957 Pgpep1 pyroglutamyl-peptidase I K01304|1|3e-119|433|mmu:66522|pyroglutamyl-peptidase [EC:3.4.19.3] GO:0044444//cytoplasmic part "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process gi|12963583|ref|NP_075706.1|/2.44366e-118/pyroglutamyl-peptidase 1 [Mus musculus] 72946 3395 17.95 18.78333333 0.065469266 Up 0.19223175 Lrrc47 leucine rich repeat containing 47 K01890|1|1e-26|125|bmy:Bm1_16240|phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] - GO:0003676//nucleic acid binding;GO:0004812//aminoacyl-tRNA ligase activity - gi|41152116|ref|NP_957678.1|/0/leucine-rich repeat-containing protein 47 [Mus musculus] 67857 1583 17.23 16.40666667 -0.070640544 Down 0.19199669 Ppp6c "protein phosphatase 6, catalytic subunit" K15498|1|0.0|646|dre:393980|serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity GO:0006464//cellular protein modification process;GO:0044772//mitotic cell cycle phase transition gi|831324638|ref|XP_012695352.1|/0/PREDICTED: serine/threonine-protein phosphatase 6 catalytic subunit [Clupea harengus] 100505025 1818 0.276666667 0.4 0.531851164 Up 0.191855655 LOC100505025 uncharacterized LOC100505025 - - - - - 68235 4381.53 3.63 3.94 0.118226081 Up 0.191752228 Mturn "maturin, neural progenitor differentiation regulator homolog (Xenopus)" K08051|1|4e-32|143|umr:103659061|pleckstrin homology domain containing family A member 8 - - - gi|576583435|ref|NP_001276669.1|/6.243e-67/maturin isoform a [Mus musculus] 68792 2917.46 3.776666667 3.463333333 -0.124952207 Down 0.191752228 Srpx2 "sushi-repeat-containing protein, X-linked 2" K19408|1|0.0|969|mmu:68792|sushi repeat-containing protein SRPX2 - - - - 320054 2097 0.21 0.11 -0.932885804 Down 0.191752228 9230116N13Rik RIKEN cDNA 9230116N13 gene - - - - - 56760 922 0.2 0.103333333 -0.952694285 Down 0.191752228 Clec1b "C-type lectin domain family 1, member b" K10070|1|2e-44|181|mmu:56760|C-type lectin domain family 1 member B GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007165//signal transduction;GO:0007165//signal transduction;GO:0007165//signal transduction gi|323714237|ref|NP_001191168.1|/3.35743e-112/C-type lectin domain family 1 member B isoform 2 [Mus musculus] 16564 6346.67 3.583333333 3.893333333 0.119703614 Up 0.191752228 Kif21a kinesin family member 21A K10395|1|0.0|2534|bacu:103012146|kinesin family member 4/21/27 - - - - 71386 992 0.203333333 0.103333333 -0.976541027 Down 0.191752228 Krtap28-13 keratin associated protein 28-13 - - - - - 269700 15496 3.903333333 3.596666667 -0.118046211 Down 0.191752228 Gm15800 predicted gene 15800 K17849|1|0.0|7920|mmu:269700|E3 ubiquitin-protein ligase HECTD4 [EC:2.3.2.26] - - - gi|359718915|ref|NP_852086.3|/0/probable E3 ubiquitin-protein ligase HECTD4 [Mus musculus] 15504 1017 0.2 0.103333333 -0.952694285 Down 0.191752228 Dnajb3 DnaJ heat shock protein family (Hsp40) member B3 K09509|1|1e-106|388|mmu:15504|DnaJ homolog subfamily B member 3 - - - - 11847 1417 0.103333333 0.2 0.952694285 Up 0.191752228 Arg2 arginase type II K01476|1|0.0|717|mmu:11847|arginase [EC:3.5.3.1] GO:0043231//intracellular membrane-bounded organelle "GO:0016813//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines;GO:0043169//cation binding;GO:0019899//enzyme binding" GO:0006941//striated muscle contraction;GO:0032496//response to lipopolysaccharide;GO:0009611//response to wounding;GO:0010243//response to organonitrogen compound;GO:0012501//programmed cell death;GO:0071385//cellular response to glucocorticoid stimulus;GO:0010958;GO:0006527//arginine catabolic process;GO:0006809//nitric oxide biosynthetic process;GO:0007565//female pregnancy;GO:0010038//response to metal ion;GO:0001101//response to acid chemical;GO:0030323//respiratory tube development;GO:0048565//digestive tract development;GO:0009746;GO:0034341//response to interferon-gamma;GO:0032769//negative regulation of monooxygenase activity;GO:0070670//response to interleukin-4;GO:0031667//response to nutrient levels "gi|148670691|gb|EDL02638.1|/0/arginase type II, partial [Mus musculus]" 192195 11293 3.91 3.6 -0.119171701 Down 0.191752228 Ash1l "ash1 (absent, small, or homeotic)-like (Drosophila)" K06101|1|0.0|5155|mmu:192195|histone-lysine N-methyltransferase ASH1L [EC:2.1.1.43] - - - gi|73622271|ref|NP_619620.3|/0/histone-lysine N-methyltransferase ASH1L [Mus musculus] 20843 5894.84 3.916666667 3.606666667 -0.118960258 Down 0.191752228 Stag2 stromal antigen 2 K06671|1|0.0|2282|cge:100757438|cohesin complex subunit SA-1/2 - - - - 268417 3970.8 10.47666667 11.03666667 0.075124739 Up 0.191620595 Zkscan17 zinc finger with KRAB and SCAN domains 17 K09229|1|0.0|1135|mmu:268417|KRAB and SCAN domains-containing zinc finger protein - - - - 19076 1990 1.06 1.24 0.226275856 Up 0.191611193 Prim2 "DNA primase, p58 subunit" K02685|1|0.0|975|mmu:19076|DNA primase large subunit [EC:2.7.7.-] GO:0031981//nuclear lumen;GO:0005657//replication fork GO:0003899//DNA-directed RNA polymerase activity;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0003676//nucleic acid binding GO:0000723//telomere maintenance;GO:0044772//mitotic cell cycle phase transition;GO:0006261//DNA-dependent DNA replication;GO:0051320;GO:0010467//gene expression gi|6679461|ref|NP_032948.1|/0/DNA primase large subunit [Mus musculus] 19017 6423.63 41.77333333 40.03 -0.061500653 Down 0.191592388 Ppargc1a "peroxisome proliferative activated receptor, gamma, coactivator 1 alpha" K07202|1|0.0|584|mmu:19017|alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005102//receptor binding;GO:0003713//transcription coactivator activity;GO:0003676//nucleic acid binding;GO:0003682//chromatin binding;GO:0005102//receptor binding;GO:0003713//transcription coactivator activity;GO:0003676//nucleic acid binding;GO:0003682//chromatin binding GO:0008202//steroid metabolic process;GO:0019395//fatty acid oxidation;GO:0008284//positive regulation of cell proliferation;GO:0044093;GO:0071241//cellular response to inorganic substance;GO:0071869//response to catecholamine;GO:0032846;GO:0019318//hexose metabolic process;GO:0022900//electron transport chain;GO:0006754//ATP biosynthetic process;GO:0007005//mitochondrion organization;GO:0032870//cellular response to hormone stimulus;GO:0010469//regulation of receptor activity;GO:0009812//flavonoid metabolic process;GO:0001666//response to hypoxia;GO:0043200//response to amino acid;GO:0006979//response to oxidative stress;GO:0014823//response to activity;GO:0009991//response to extracellular stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0009893//positive regulation of metabolic process;GO:0014909//smooth muscle cell migration;GO:0070542//response to fatty acid;GO:0043066//negative regulation of apoptotic process;GO:0008202//steroid metabolic process;GO:0019395//fatty acid oxidation;GO:0008284//positive regulation of cell proliferation;GO:0044093;GO:0071241//cellular response to inorganic substance;GO:0071869//response to catecholamine;GO:0032846;GO:0019318//hexose metabolic process;GO:0022900//electron transport chain;GO:0006754//ATP biosynthetic process;GO:0007005//mitochondrion organization;GO:0032870//cellular response to hormone stimulus;GO:0010469//regulation of receptor activity;GO:0009812//flavonoid metabolic process;GO:0001666//response to hypoxia;GO:0043200//response to amino acid;GO:0006979//response to oxidative stress;GO:0014823//response to activity;GO:0009991//response to extracellular stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0009893//positive regulation of metabolic process;GO:0014909//smooth muscle cell migration;GO:0070542//response to fatty acid;GO:0043066//negative regulation of apoptotic process "gi|45219869|gb|AAH66868.1|/0/Peroxisome proliferative activated receptor, gamma, coactivator 1 alpha [Mus musculus]" 74838 6090 7.276666667 7.726666667 0.086568436 Up 0.191582985 Naa15 "N(alpha)-acetyltransferase 15, NatA auxiliary subunit" K00670|1|0.0|1660|mmu:74838|peptide alpha-N-acetyltransferase [EC:2.3.1.88] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005488//binding;GO:0016407//acetyltransferase activity "GO:0048869//cellular developmental process;GO:0006473//protein acetylation;GO:0006351//transcription, DNA-templated" "gi|225543482|ref|NP_444319.3|/0/N-alpha-acetyltransferase 15, NatA auxiliary subunit [Mus musculus]" 68176 1077 7.69 7.24 -0.086993901 Down 0.191582985 Fam212a "family with sequence similarity 212, member A" - - - GO:0007399//nervous system development gi|283837813|ref|NP_080873.2|/1.39756e-142/protein FAM212A [Mus musculus] 67511 1463 41.38333333 43.11333333 0.059084254 Up 0.191526571 Tmed9 transmembrane emp24 protein transport domain containing 9 K20346|1|1e-110|402|pale:102884449|p24 family protein alpha GO:0031224//intrinsic component of membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0031090//organelle membrane;GO:0005798//Golgi-associated vesicle GO:0005488//binding GO:0035964//COPI-coated vesicle budding;GO:0016482//cytosolic transport;GO:0006886//intracellular protein transport gi|74139306|dbj|BAE40800.1|/7.2265e-129/unnamed protein product [Mus musculus] 73737 674 40.24666667 41.97666667 0.060718307 Up 0.191526571 1110008P14Rik RIKEN cDNA 1110008P14 gene K14530|1|4e-06|53.5|cqu:CpipJ_CPIJ008180|ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5] - - - gi|37574084|ref|NP_932118.1|/6.32748e-41/UPF0184 protein C9orf16 homolog [Mus musculus] 74057 768 0.156666667 0.07 -1.162271429 Down 0.191488962 4933405D12Rik RIKEN cDNA 4933405D12 gene - - - - - 271944 1316 0.156666667 0.07 -1.162271429 Down 0.191488962 C2cd4d C2 calcium-dependent domain containing 4D - - - - gi|209870113|ref|NP_001129589.1|/9.70652e-147/C2 calcium-dependent domain-containing protein 4D [Mus musculus] 104444 1075 38.48666667 40.20333333 0.062956398 Up 0.191479559 Rexo2 RNA exonuclease 2 K13288|1|2e-104|381|mmu:104444|oligoribonuclease [EC:3.1.-.-] GO:0016020//membrane;GO:0031981//nuclear lumen GO:0004527//exonuclease activity;GO:0097159//organic cyclic compound binding GO:0006725//cellular aromatic compound metabolic process gi|74214051|dbj|BAE29442.1|/1.27878e-103/unnamed protein product [Mus musculus] 100504069 908 0.39 0.52 0.415037499 Up 0.191451352 Gm15915 predicted gene 15915 - - - - - 55991 2112 0.753333333 0.91 0.272578179 Up 0.191385535 Panx1 pannexin 1 K03443|1|0.0|773|mmu:55991|pannexin GO:0005911//cell-cell junction;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0042995//cell projection GO:0022842;GO:0046983//protein dimerization activity;GO:0005261//cation channel activity;GO:0003779//actin binding;GO:0005243//gap junction channel activity GO:0032730//positive regulation of interleukin-1 alpha production;GO:0050663//cytokine secretion;GO:0006816//calcium ion transport;GO:0046683//response to organophosphorus;GO:0007154//cell communication;GO:0032731//positive regulation of interleukin-1 beta production;GO:0051259//protein oligomerization;GO:0006950//response to stress gi|8515126|gb|AAF75838.1|AF207817_1/0/putative gap junction protein pannexin [Mus musculus] 13478 1920 16.43333333 17.23333333 0.068576634 Up 0.191376133 Dpagt1 dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) K01001|1|0.0|696|mmu:13478|UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase [EC:2.7.8.15] GO:0031227//intrinsic component of endoplasmic reticulum membrane "GO:0016780//phosphotransferase activity, for other substituted phosphate groups" GO:0016094;GO:0006040//amino sugar metabolic process;GO:0006461//protein complex assembly;GO:0006486//protein glycosylation gi|31982409|ref|NP_031901.2|/0/UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase [Mus musculus] 56307 4990 17.85666667 17.05333333 -0.066409032 Down 0.191376133 Metap2 methionine aminopeptidase 2 K01265|1|0.0|851|mmu:56307|methionyl aminopeptidase [EC:3.4.11.18] GO:0044424 GO:0043169//cation binding;GO:0008238//exopeptidase activity;GO:0008237//metallopeptidase activity GO:0018193//peptidyl-amino acid modification;GO:0051604//protein maturation gi|9789873|ref|NP_062622.1|/0/methionine aminopeptidase 2 [Mus musculus] 70560 4388 1.38 1.583333333 0.198296746 Up 0.191366731 Wars2 tryptophanyl tRNA synthetase 2 (mitochondrial) K01867|1|3e-180|635|mmu:70560|tryptophanyl-tRNA synthetase [EC:6.1.1.2] - - - "gi|31543952|ref|NP_081738.2|/2.2132e-179/tryptophan--tRNA ligase, mitochondrial precursor [Mus musculus]" 320844 2549 1.55 1.353333333 -0.195750989 Down 0.191366731 Amigo3 adhesion molecule with Ig like domain 3 K19511|1|3e-18|96.7|dgr:Dgri_GH15071|peroxidase [EC:1.11.1.7];K16354|2|4e-18|96.3|bfo:BRAFLDRAFT_89096|leucine-rich repeat and fibronectin type-III domain-containing protein 1;K16351|3|4e-18|96.3|ssc:100521592|netrin-G2 ligand GO:0031224//intrinsic component of membrane - GO:0048731//system development;GO:0016337//single organismal cell-cell adhesion gi|37360576|dbj|BAC98266.1|/0/mKIAA1851 protein [Mus musculus] 226844 3230.04 1.36 1.56 0.197939378 Up 0.191366731 Mfsd7b major facilitator superfamily domain containing 7B "K08220|1|4e-145|518|mmu:226844|MFS transporter, FLVCR family, feline leukemia virus subgroup C receptor-related protein" - GO:0051184 GO:0030099//myeloid cell differentiation;GO:0015886//heme transport;GO:0030326//embryonic limb morphogenesis;GO:0035265//organ growth gi|26332603|dbj|BAC30019.1|/7.69569e-125/unnamed protein product [Mus musculus] 380629 3667 5.473333333 5.093333333 -0.103809584 Down 0.191338523 Heca "hdc homolog, cell cycle regulator" K10867|1|3e-26|124|gja:107105989|nijmegen breakage syndrome protein 1 - - - - 328572 8749 5.426666667 5.046666667 -0.104735494 Down 0.191338523 Ep300 E1A binding protein p300 K04498|1|0.0|2074|mmu:328572|E1A/CREB-binding protein [EC:2.3.1.48] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044427 GO:0035258//steroid hormone receptor binding;GO:0046872//metal ion binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0008080//N-acetyltransferase activity;GO:0003682//chromatin binding;GO:0019901//protein kinase binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding "GO:0001932//regulation of protein phosphorylation;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0030521//androgen receptor signaling pathway;GO:0001501//skeletal system development;GO:0009952//anterior/posterior pattern specification;GO:0014706//striated muscle tissue development;GO:0031960//response to corticosteroid;GO:0006508//proteolysis;GO:0045214//sarcomere organization;GO:0009101//glycoprotein biosynthetic process;GO:0000060//protein import into nucleus, translocation;GO:0043921;GO:0034622//cellular macromolecular complex assembly;GO:0030307//positive regulation of cell growth;GO:0043393//regulation of protein binding;GO:0006474//N-terminal protein amino acid acetylation;GO:0009892//negative regulation of metabolic process;GO:0008361//regulation of cell size;GO:0010038//response to metal ion;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0051099//positive regulation of binding;GO:0009746;GO:0030323//respiratory tube development;GO:0006412//translation;GO:0009306//protein secretion" gi|94421034|ref|NP_808489.4|/0/histone acetyltransferase p300 [Mus musculus] 67467 5448 5.003333333 5.38 0.104716602 Up 0.191338523 Gpalpp1 GPALPP motifs containing 1 - - - - gi|50511061|dbj|BAD32516.1|/1.53293e-177/mKIAA1704 protein [Mus musculus] 68705 1467 5.443333333 5.82 0.096528768 Up 0.191338523 Gtf2f2 "general transcription factor IIF, polypeptide 2" K03139|1|6e-140|499|mmu:68705|transcription initiation factor TFIIF subunit beta [EC:3.6.4.12] GO:0005856//cytoskeleton;GO:0005667//transcription factor complex "GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled" GO:0006366//transcription from RNA polymerase II promoter gi|39930425|ref|NP_081092.1|/5.09861e-139/general transcription factor IIF subunit 2 [Mus musculus] 19775 7651 5.903333333 5.523333333 -0.09599061 Down 0.191338523 Xpr1 xenotropic and polytropic retrovirus receptor 1 - GO:0031224//intrinsic component of membrane - GO:0051707//response to other organism gi|6755330|ref|NP_035403.1|/0/xenotropic and polytropic retrovirus receptor 1 [Mus musculus] 231130 1966 5.24 5.616666667 0.100147374 Up 0.191338523 Tnip2 TNFAIP3 interacting protein 2 K16456|1|7e-20|101|bfo:BRAFLDRAFT_124674|centrosomal protein CEP55;K10352|2|7e-09|65.1|fca:101093785|myosin heavy chain;K06102|3|3e-08|63.2|clv:102086111|cingulin GO:0044444//cytoplasmic part GO:0043130//ubiquitin binding;GO:0019900//kinase binding GO:0032496//response to lipopolysaccharide;GO:0006366//transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0031647//regulation of protein stability;GO:0002224//toll-like receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0002696//positive regulation of leukocyte activation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0042113//B cell activation "gi|148705507|gb|EDL37454.1|/0/TNFAIP3 interacting protein 2, isoform CRA_a, partial [Mus musculus]" 27416 4730.02 5.726666667 5.343333333 -0.099955611 Down 0.191338523 Abcc5 "ATP-binding cassette, sub-family C (CFTR/MRP), member 5" "K05668|1|5e-112|406|mmu:27416|ATP-binding cassette, subfamily C (CFTR/MRP), member 5" GO:0016021//integral component of membrane;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008509//anion transmembrane transporter activity;GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0015405 GO:0044763;GO:0043434//response to peptide hormone;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006820//anion transport;GO:0009154//purine ribonucleotide catabolic process;GO:0002237//response to molecule of bacterial origin;GO:0009154//purine ribonucleotide catabolic process;GO:0044763;GO:0043434//response to peptide hormone;GO:0002237//response to molecule of bacterial origin;GO:0051234//establishment of localization gi|66932956|ref|NP_789809.1|/1.42027e-117/multidrug resistance-associated protein 5 isoform 2 [Mus musculus] 239083 1508 0.07 0.01 -2.807354922 Down 0.191329121 Ccnb1ip1 cyclin B1 interacting protein 1 K10639|1|4e-159|563|mmu:239083|E3 ubiquitin-protein ligase CCNP1IP1 [EC:2.3.2.27] - - GO:0007281//germ cell development;GO:0007129//synapsis;GO:0012501//programmed cell death;GO:0040007//growth;GO:0001824//blastocyst development gi|162287146|ref|NP_001104589.1|/2.98406e-158/E3 ubiquitin-protein ligase CCNB1IP1 [Mus musculus] 100038657 794 0.01 0.07 2.807354922 Up 0.191329121 7420461P10Rik RIKEN cDNA 7420461P10 gene - - - - gi|294831984|ref|NP_001171052.1|/1.93328e-67/uncharacterized protein LOC100038657 [Mus musculus] 627782 1472 0.01 0.07 2.807354922 Up 0.191329121 Gm6787 "proteasome (prosome, macropain) subunit, beta type 7 pseudogene" K02739|1|8e-66|224|bacu:102999149|20S proteasome subunit beta 2 [EC:3.4.25.1] - - - - 74879 780 0.01 0.07 2.807354922 Up 0.191329121 4930461G14Rik RIKEN cDNA 4930461G14 gene - - - - - 74174 740 0.073333333 0.01 -2.874469118 Down 0.191329121 Gtsf1 gametocyte specific factor 1 K02728|1|1e-08|62.4|hst:105180554|20S proteasome subunit alpha 3 [EC:3.4.25.1] GO:0044424 GO:0043169//cation binding - gi|564362011|ref|XP_006242465.1|/4.50831e-105/PREDICTED: gametocyte-specific factor 1 isoform X2 [Rattus norvegicus] 20771 783 0.07 0.01 -2.807354922 Down 0.191329121 Mucl1 mucin-like 1 - - - - gi|6678123|ref|NP_033294.1|/6.81729e-95/mucin-like 1 Spt-2 precursor [Mus musculus] 14432 1316 0.01 0.073333333 2.874469118 Up 0.191329121 Gap43 growth associated protein 43 K20041|1|1e-49|199|mmu:14432|neuromodulin GO:0043005//neuron projection;GO:0016020//membrane - GO:0007411//axon guidance gi|6679935|ref|NP_032109.1|/9.34142e-49/neuromodulin [Mus musculus] 545650 1462 0.01 0.073333333 2.874469118 Up 0.191329121 Gm13277 predicted gene 13277 K05414|1|7e-38|160|cge:100763520|interferon alpha GO:0044421 GO:0005102//receptor binding GO:0007166//cell surface receptor signaling pathway;GO:0030098//lymphocyte differentiation;GO:0002252;GO:0007049//cell cycle;GO:0012501//programmed cell death gi|149588682|ref|NP_001092311.1|/1.88304e-101/interferon zeta-like precursor [Mus musculus] 76072 1404 0.073333333 0.01 -2.874469118 Down 0.191329121 Rnf183 ring finger protein 183 - GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding - "gi|149059623|gb|EDM10561.1|/4.5077e-105/rCG55211, isoform CRA_a [Rattus norvegicus]" 78219 781 0.01 0.07 2.807354922 Up 0.191329121 4930568E12Rik RIKEN cDNA 4930568E12 gene - - - - - 639658 1295 0.01 0.073333333 2.874469118 Up 0.191329121 Gm13807 predicted gene 13807 - - - - "gi|148695674|gb|EDL27621.1|/4.51486e-56/mCG144777, partial [Mus musculus]" 77682 737 0.073333333 0.01 -2.874469118 Down 0.191329121 9230102O04Rik RIKEN cDNA 9230102O04 gene - - - - - 100042926 683 0.01 0.07 2.807354922 Up 0.191329121 Gm13546 predicted gene 13546 - - - - gi|148694992|gb|EDL26939.1|/2.27363e-37/mCG1040456 [Mus musculus] 21461 2314 0.07 0.01 -2.807354922 Down 0.191329121 Tcp10a t-complex protein 10a K11502|1|1e-83|313|amj:102561979|centromere protein J - - - gi|568998138|ref|XP_006523342.1|/0/PREDICTED: t-complex protein 10c isoform X3 [Mus musculus] 78457 780 0.01 0.07 2.807354922 Up 0.191329121 1700054A03Rik RIKEN cDNA 1700054A03 gene - - - - gi|148669739|gb|EDL01686.1|/1.38601e-38/mCG1025989 [Mus musculus] 246278 1530 0.07 0.01 -2.807354922 Down 0.191329121 Cd207 CD207 antigen K06561|1|0.0|651|mmu:246278|CD207 antigen GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0002252 "gi|148666678|gb|EDK99094.1|/0/CD 207 antigen, isoform CRA_a, partial [Mus musculus]" 100502636 1435 0.073333333 0.01 -2.874469118 Down 0.191329121 Gm19299 "predicted gene, 19299" "K03847|1|2e-10|69.7|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - - 15414 1344 0.01 0.07 2.807354922 Up 0.191329121 Hoxb6 homeobox B6 K09306|1|7e-92|340|rno:497986|homeobox protein HoxA/B/C6 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0003002//regionalization;GO:0001501//skeletal system development;GO:0048562//embryonic organ morphogenesis;GO:0006351//transcription, DNA-templated;GO:0048872//homeostasis of number of cells" gi|568971794|ref|XP_006532355.1|/3.17141e-92/PREDICTED: homeobox protein Hox-B6 isoform X1 [Mus musculus] 242523 4073 0.01 0.07 2.807354922 Up 0.191329121 Dmrta1 doublesex and mab-3 related transcription factor like family A1 K19491|1|0.0|860|mmu:242523|doublesex- and mab-3-related transcription factor 4/5 GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0003006//developmental process involved in reproduction" gi|28316744|ref|NP_783578.1|/0/doublesex- and mab-3-related transcription factor A1 [Mus musculus] 627821 782 0.073333333 0.01 -2.874469118 Down 0.191329121 Gm6792 predicted gene 6792 K09230|1|7e-12|67.8|cge:103162169|SCAN domain-containing zinc finger protein - - - gi|294459930|ref|NP_001170887.1|/5.43236e-75/epididymis-specific protein isoform 1 precursor [Mus musculus] 224180 807 0.01 0.07 2.807354922 Up 0.191329121 Gm4827 predicted gene 4827 - - - - - 78552 867 0.07 0.01 -2.807354922 Down 0.191329121 E130201H02Rik Y box protein 1 pseudogene K09276|1|1e-69|261|chx:102184870|Y-box-binding protein 1 GO:0043005//neuron projection;GO:0035770//ribonucleoprotein granule;GO:0005681//spliceosomal complex;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0003723//RNA binding;GO:0043566//structure-specific DNA binding GO:0008286//insulin receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0051146//striated muscle cell differentiation;GO:0043009//chordate embryonic development;GO:0048255//mRNA stabilization;GO:0006396//RNA processing;GO:0048522 "gi|148685263|gb|EDL17210.1|/8.08203e-81/mCG147570, partial [Mus musculus]" 18811 790 0.073333333 0.01 -2.874469118 Down 0.191329121 Prl2c2 "prolactin family 2, subfamily c, member 2" K05439|1|8e-56|219|cge:100761279|prolactin GO:0043231//intracellular membrane-bounded organelle;GO:0044421 GO:0005102//receptor binding GO:0001525//angiogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0007405//neuroblast proliferation;GO:0045445//myoblast differentiation;GO:0030033//microvillus assembly;GO:0010595//positive regulation of endothelial cell migration gi|13654251|ref|NP_112468.1|/2.81964e-119/prolactin-2C2 precursor [Mus musculus] 407795 1481 0.01 0.073333333 2.874469118 Up 0.191329121 BC030870 cDNA sequence BC030870 - - - - - 100038607 2419 0.07 0.01 -2.807354922 Down 0.191329121 Gm10636 predicted gene 10636 - - - - gi|74183222|dbj|BAE22546.1|/1.79284e-52/unnamed protein product [Mus musculus] 622301 779 0.07 0.01 -2.807354922 Down 0.191329121 Rhox2h reproductive homeobox 2H - GO:0043231//intracellular membrane-bounded organelle - - gi|154689736|ref|NP_001093935.1|/1.32084e-89/reproductive homeobox 2H [Mus musculus] 22362 772 0.01 0.07 2.807354922 Up 0.191329121 Vpreb1 pre-B lymphocyte gene 1 K06553|1|2e-80|301|mmu:22362|pre-B lymphocyte gene GO:0009986//cell surface;GO:0016020//membrane GO:0005488//binding GO:0042592//homeostatic process;GO:0048534//hematopoietic or lymphoid organ development;GO:0002440;GO:0042113//B cell activation;GO:0032535//regulation of cellular component size gi|8850238|ref|NP_058678.1|/1.21848e-79/immunoglobulin iota chain precursor [Mus musculus] 114868 3089 0.01 0.073333333 2.874469118 Up 0.191329121 Psg25 pregnancy-specific glycoprotein 25 K06499|1|7e-116|421|mmu:384557|carcinoembryonic antigen-related cell adhesion molecule - GO:0005515//protein binding GO:0001525//angiogenesis;GO:0044703;GO:0038044;GO:0002376//immune system process;GO:0010467//gene expression;GO:0009690//cytokinin metabolic process;GO:0032653 gi|75832037|ref|NP_473401.1|/0/pregnancy-specific glycoprotein 25 [Mus musculus] 67859 781 0.01 0.07 2.807354922 Up 0.191329121 Cysrt1 cysteine rich tail 1 - - - - gi|258645158|ref|NP_080691.2|/2.06153e-50/cysteine-rich tail protein 1 [Mus musculus] 387221 73 0.01 0.07 2.807354922 Up 0.191329121 Mir27b microRNA 27b - - - - - 75315 793 0.073333333 0.01 -2.874469118 Down 0.191329121 4930553C11Rik RIKEN cDNA 4930553C11 gene - - - - - 632971 682 0.01 0.07 2.807354922 Up 0.191329121 Rergl RERG/RAS-like K17198|1|1e-114|414|mmu:632971|Ras-related and estrogen-regulated growth inhibitor-like protein - GO:0032550 - gi|189339211|ref|NP_001121562.1|/7.4883e-114/ras-related and estrogen-regulated growth inhibitor-like protein [Mus musculus] 260298 1479 0.073333333 0.01 -2.874469118 Down 0.191329121 Fev FEV (ETS oncogene family) K09437|1|4e-92|341|ngi:103727813|ETS oncogene family protein FEV GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0043566//structure-specific DNA binding "GO:0048731//system development;GO:0048469//cell maturation;GO:0006351//transcription, DNA-templated;GO:0001708//cell fate specification" gi|3033419|gb|AAC12859.1|/5.00151e-113/ETS domain transcription factor PET-1 [Rattus norvegicus] 67315 1505 0.07 0.01 -2.807354922 Down 0.191329121 Ceacam12 carcinoembryonic antigen-related cell adhesion molecule 12 K06499|1|2e-146|521|mmu:67315|carcinoembryonic antigen-related cell adhesion molecule - - - - 78512 775 0.07 0.01 -2.807354922 Down 0.191329121 3300005D01Rik RIKEN cDNA 3300005D01 gene - - - - "gi|148669714|gb|EDL01661.1|/2.12048e-39/mCG62490, partial [Mus musculus]" 22144 1540 0.07 0.01 -2.807354922 Down 0.191329121 Tuba3a "tubulin, alpha 3A" K07374|1|0.0|861|ocu:100349209|tubulin alpha GO:0032991//macromolecular complex;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0044763;GO:0006458//'de novo' protein folding;GO:0043623//cellular protein complex assembly;GO:0009154//purine ribonucleotide catabolic process gi|291414495|ref|XP_002723497.1|/0/PREDICTED: tubulin alpha-3E chain [Oryctolagus cuniculus] 240916 1533 0.073333333 0.01 -2.874469118 Down 0.191329121 Vsig8 V-set and immunoglobulin domain containing 8 K06788|1|8e-23|110|ola:101174768|coxsackievirus and adenovirus receptor - - - gi|229892207|ref|NP_808391.2|/0/V-set and immunoglobulin domain-containing protein 8 precursor [Mus musculus] 105827746 728 0.01 0.073333333 2.874469118 Up 0.191329121 Gm11729 predicted gene 11729 - - - - "gi|148702671|gb|EDL34618.1|/1.61993e-30/mCG1042049, partial [Mus musculus]" 231605 1561 0.01 0.07 2.807354922 Up 0.191329121 Galnt9 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 K00710|1|0.0|1176|ngi:103750603|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0008376//acetylgalactosaminyltransferase activity;GO:0016740//transferase activity;GO:0016740//transferase activity GO:0006464//cellular protein modification process gi|169790935|ref|NP_938048.2|/1.50235e-144/polypeptide N-acetylgalactosaminyltransferase 9 isoform A [Mus musculus] 70045 756 0.01 0.07 2.807354922 Up 0.191329121 2610528A11Rik RIKEN cDNA 2610528A11 gene - - - - gi|148692951|gb|EDL24898.1|/3.23074e-29/mCG1034617 [Mus musculus] 57260 1439 0.073333333 0.01 -2.874469118 Down 0.191329121 Ltb4r2 leukotriene B4 receptor 2 K04297|1|5e-125|450|mmu:57260|leukotriene B4 receptor 2 GO:0016021//integral component of membrane GO:0004974//leukotriene receptor activity GO:0016477//cell migration;GO:0007166//cell surface receptor signaling pathway gi|568988316|ref|XP_006519386.1|/1.70523e-131/PREDICTED: leukotriene B4 receptor 2 isoform X2 [Mus musculus] 75258 792 0.073333333 0.01 -2.874469118 Down 0.191329121 4930563M21Rik RIKEN cDNA 4930563M21 gene - - - - - 11604 667 0.01 0.07 2.807354922 Up 0.191329121 Agrp agouti related neuropeptide K05231|1|7e-62|238|mmu:11604|agouti related protein GO:0044297//cell body;GO:0044431//Golgi apparatus part;GO:0044421;GO:0044297//cell body;GO:0044431//Golgi apparatus part;GO:0044421 GO:0005179//hormone activity;GO:0005179//hormone activity GO:0009416//response to light stimulus;GO:0007565//female pregnancy;GO:0048511//rhythmic process;GO:0043434//response to peptide hormone;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007631//feeding behavior;GO:0009416//response to light stimulus;GO:0007565//female pregnancy;GO:0048511//rhythmic process;GO:0043434//response to peptide hormone;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007631//feeding behavior gi|6671529|ref|NP_031453.1|/5.45583e-61/agouti-related protein precursor [Mus musculus] 66494 1103 40.25333333 41.95666667 0.059791808 Up 0.191319719 Prelid1 PRELI domain containing 1 K15588|1|4e-30|134|apla:101789499|histone-lysine N-methyltransferase NSD1 [EC:2.1.1.43];K07912|2|1e-07|59.7|shr:100913460|Ras-related protein Rab-24 GO:0031981//nuclear lumen - - "gi|46518501|ref|NP_079872.4|/5.06279e-103/PRELI domain-containing protein 1, mitochondrial precursor [Mus musculus]" 109294 7012 2.776666667 2.513333333 -0.143751972 Down 0.191263304 Prex2 "phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2" "K17588|1|1e-78|298|mmu:109294|phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein" - - - - 107375 1833 2.643333333 2.903333333 0.135351853 Up 0.191263304 Slc25a45 "solute carrier family 25, member 45" "K15123|1|3e-165|584|mmu:107375|solute carrier family 25, member 45/47" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763 "gi|18381035|gb|AAH22156.1|/1.72863e-166/Slc25a45 protein, partial [Mus musculus]" 74182 3642.69 40.55666667 38.86333333 -0.061529436 Down 0.191263304 Gpcpd1 glycerophosphocholine phosphodiesterase 1 K18695|1|0.0|1312|mmu:74182|glycerophosphocholine phosphodiesterase GPCPD1 [EC:3.1.4.2] - - - - 56264 2434 2.48 2.736666667 0.142079601 Up 0.191263304 Cpxm1 carboxypeptidase X 1 (M14 family) K08638|1|0.0|1428|mmu:56264|carboxypeptidase X1 [EC:3.4.17.-] GO:0044421 GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0022610;GO:0019538//protein metabolic process gi|228008326|ref|NP_062670.2|/0/probable carboxypeptidase X1 precursor [Mus musculus] 99334 4016.93 2.43 2.686666667 0.144861024 Up 0.191263304 Zscan29 zinc finger SCAN domains 29 K09230|1|1e-131|473|mmu:99334|SCAN domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0044764;GO:0006351//transcription, DNA-templated" gi|595763471|ref|NP_001277749.1|/0/zinc finger and SCAN domain-containing protein 29 isoform b [Mus musculus] 51897 3573 39.57666667 37.89333333 -0.062706053 Down 0.191178683 Atg13 autophagy related 13 K08331|1|0.0|863|mmu:51897|autophagy-related protein 13 - - - - 329731 4317 0.633333333 0.786666667 0.312787441 Up 0.191169281 Fam19a3 "family with sequence similarity 19, member A3" - - - - "gi|148675620|gb|EDL07567.1|/1.7025e-99/RIKEN cDNA 7530404M11, partial [Mus musculus]" 329851 1759 0.166666667 0.076666667 -1.120294234 Down 0.191112866 Gm12530 predicted gene 12530 - - - - - 227615 914 4.496666667 4.16 -0.112272414 Down 0.191084659 Tmem203 transmembrane protein 203 K14527|1|2e-14|82.0|dpo:Dpse_GA22553|ribonuclease P/MRP protein subunit RPP20 [EC:3.1.26.5] - - - - 19891 1782 4.346666667 4.683333333 0.107626261 Up 0.191084659 Rpa2 replication protein A2 K10739|1|4e-144|514|mmu:19891|replication factor A2 GO:0043234//protein complex;GO:0016604//nuclear body GO:0019902//phosphatase binding;GO:0043566//structure-specific DNA binding GO:0006281//DNA repair;GO:0000018//regulation of DNA recombination gi|110625961|ref|NP_035414.3|/3.37103e-143/replication protein A 32 kDa subunit [Mus musculus] 69440 4716 4.236666667 4.573333333 0.110316451 Up 0.191084659 Dennd6b DENN/MADD domain containing 6B K17654|1|1e-32|145|tsp:Tsp_05738|mitochondrial ribonuclease P protein 1 [EC:2.1.1.-] GO:0005768//endosome GO:0005088//Ras guanyl-nucleotide exchange factor activity - gi|49355814|ref|NP_081357.2|/0/protein DENND6B [Mus musculus] 207818 1138.8 14.99333333 15.78 0.073776045 Up 0.191084659 Smagp small cell adhesion glycoprotein - GO:0012506//vesicle membrane;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0012506//vesicle membrane;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0031982//vesicle;GO:0016020//membrane;GO:0031981//nuclear lumen;GO:0031982//vesicle;GO:0016020//membrane;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0031981//nuclear lumen - - "gi|148672128|gb|EDL04075.1|/5.4291e-56/cDNA sequence BC004728, partial [Mus musculus]" 233875 1143 17.62 16.83 -0.066178748 Down 0.191084659 Ino80e INO80 complex subunit E K11669|1|2e-38|162|mmu:233875|INO80 complex subunit E - - - gi|23956376|ref|NP_705808.1|/1.33482e-37/INO80 complex subunit E [Mus musculus] 107939 5602 9.566666667 9.02 -0.084888898 Down 0.191075257 Pom121 nuclear pore membrane protein 121 K14316|1|0.0|1085|mmu:107939|nuclear pore complex protein Nup121 GO:0005635//nuclear envelope;GO:0044425 GO:0005198//structural molecule activity GO:0006997//nucleus organization;GO:0006810//transport gi|156231054|ref|NP_683734.2|/0/nuclear envelope pore membrane protein POM 121 [Mus musculus] 74157 6396 10.37333333 9.826666667 -0.078105536 Down 0.191075257 Cmtr1 cap methyltransferase 1 K14589|1|0.0|1679|mmu:74157|cap1 methyltransferase [EC:2.1.1.57] GO:0031981//nuclear lumen "GO:0008171//O-methyltransferase activity;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds" GO:0001510//RNA methylation;GO:0032446//protein modification by small protein conjugation;GO:0033554//cellular response to stress;GO:0006397//mRNA processing gi|21311939|ref|NP_083067.1|/0/cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 [Mus musculus] 74200 2999 9.926666667 9.38 -0.081721425 Down 0.191075257 2810403A07Rik RIKEN cDNA 2810403A07 gene - - - - gi|254692930|ref|NP_083090.2|/0/UPF0469 protein KIAA0907 [Mus musculus] 77582 2880 9.99 10.54 0.077318284 Up 0.191075257 Mboat7 membrane bound O-acyltransferase domain containing 7 K13516|1|0.0|862|mmu:77582|lysophospholipid acyltransferase 7 [EC:2.3.1.-] GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane "GO:0005488//binding;GO:0016746//transferase activity, transferring acyl groups" GO:0046488//phosphatidylinositol metabolic process;GO:0007420//brain development gi|31542014|ref|NP_084210.2|/0/lysophospholipid acyltransferase 7 [Mus musculus] 12091 2388.78 9.933333333 10.48666667 0.07820634 Up 0.191075257 Glb1 "galactosidase, beta 1" K12309|1|0.0|1304|mmu:12091|beta-galactosidase [EC:3.2.1.23] GO:0000323//lytic vacuole;GO:0005764//lysosome;GO:0005764//lysosome GO:0015925//galactosidase activity;GO:0097367//carbohydrate derivative binding;GO:0015925//galactosidase activity;GO:0097367//carbohydrate derivative binding;GO:0015925//galactosidase activity;GO:0097367//carbohydrate derivative binding GO:0006012//galactose metabolic process;GO:0006012//galactose metabolic process;GO:0006790//sulfur compound metabolic process;GO:0006664//glycolipid metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0006012//galactose metabolic process;GO:0006790//sulfur compound metabolic process;GO:0006664//glycolipid metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006027//glycosaminoglycan catabolic process gi|6753190|ref|NP_033882.1|/0/beta-galactosidase preproprotein [Mus musculus] 66959 1747 0.4 0.28 -0.514573173 Down 0.191028245 Dusp26 dual specificity phosphatase 26 (putative) K14165|1|9e-112|406|mmu:66959|atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] - - - gi|640815631|ref|XP_008064591.1|/8.71237e-112/PREDICTED: dual specificity protein phosphatase 26 [Tarsius syrichta] 101447999 1432 0.4 0.28 -0.514573173 Down 0.191028245 Mirc35hg "microRNA cluster 35, host gene" - - - - - 78416 1072 0.28 0.4 0.514573173 Up 0.191028245 Rnase6 "ribonuclease, RNase A family, 6" K01172|1|2e-75|285|mmu:78416|ribonuclease 6/7/8 [EC:3.1.27.-] - "GO:0016892//endoribonuclease activity, producing 3'-phosphomonoesters;GO:0097159//organic cyclic compound binding" - gi|257196221|ref|NP_084374.2|/1.24145e-74/ribonuclease K6 precursor [Mus musculus] 70448 679 0.39 0.273333333 -0.512812715 Down 0.191028245 Atad3aos "ATPase family, AAA domain containing 3A, opposite strand" - - - - - 20259 2708 0.276666667 0.393333333 0.507603618 Up 0.191028245 Scin scinderin K05768|1|0.0|1006|mmu:20259|gelsolin GO:0032991//macromolecular complex;GO:0043232;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex GO:0035091//phosphatidylinositol binding;GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0043168//anion binding GO:0002062//chondrocyte differentiation;GO:0030835//negative regulation of actin filament depolymerization;GO:0030219//megakaryocyte differentiation;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0006887//exocytosis;GO:0044763;GO:0050794//regulation of cellular process "gi|148704880|gb|EDL36827.1|/0/scinderin, partial [Mus musculus]" 16322 1463 2.966666667 3.25 0.131596883 Up 0.190981233 Inha inhibin alpha "K05500|1|0.0|674|mmu:16322|inhibin, alpha" GO:0044297//cell body;GO:0043511;GO:0031513//nonmotile primary cilium GO:0005102//receptor binding;GO:0046983//protein dimerization activity GO:0012502//induction of programmed cell death;GO:0007049//cell cycle;GO:0032277//negative regulation of gonadotropin secretion;GO:0020027//hemoglobin metabolic process;GO:0008283//cell proliferation;GO:0008406//gonad development gi|40254367|ref|NP_034694.3|/0/inhibin alpha chain precursor [Mus musculus] 69020 1816 2.993333333 3.27 0.127537691 Up 0.190981233 Zfp707 zinc finger protein 707 K09228|1|0.0|734|mmu:69020|KRAB domain-containing zinc finger protein GO:0044464 GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" "gi|148697563|gb|EDL29510.1|/0/mCG142742, isoform CRA_e, partial [Mus musculus]" 71176 2159 0.296666667 0.186666667 -0.668378509 Down 0.190793185 Fbxo24 F-box protein 24 K10304|1|0.0|1152|mmu:71176|F-box protein 24 - - - gi|755514673|ref|XP_011239258.1|/0/PREDICTED: F-box only protein 24 isoform X1 [Mus musculus] 619321 954 0.646666667 0.506666667 -0.351985329 Down 0.190708564 9530052E02Rik RIKEN cDNA 9530052E02 gene K07187|1|2e-09|65.9|mmu:384783|insulin receptor substrate 2 - - - - 319682 1567 0.626666667 0.49 -0.354916507 Down 0.190708564 D830026I12Rik RIKEN cDNA D830026I12 gene - - - - "gi|148681943|gb|EDL13890.1|/2.95645e-26/mCG144642, partial [Mus musculus]" 233836 2341 0.103333333 0.026666667 -1.95419631 Down 0.19061454 Slc5a11 "solute carrier family 5 (sodium/glucose cotransporter), member 11" "K14391|1|0.0|1217|mmu:233836|solute carrier family 5 (sodium/myo-inositol cotransporter), member 11" GO:0044459;GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0012501//programmed cell death;GO:0030001//metal ion transport "gi|148685350|gb|EDL17297.1|/0/solute carrier family 5 (sodium/glucose cotransporter), member 11, isoform CRA_b [Mus musculus]" 13034 2120 0.03 0.11 1.874469118 Up 0.19061454 Ctse cathepsin E K01382|1|0.0|789|mmu:13034|cathepsin E [EC:3.4.23.34] - - - - 77609 2218.01 0.026666667 0.103333333 1.95419631 Up 0.19061454 Ccdc151 coiled-coil domain containing 151 K17639|1|3e-82|308|ecb:100146392|ral guanine nucleotide dissociation stimulator-like 3;K20478|2|3e-15|86.7|dre:557772|golgin subfamily B member 1 - - - - 107607 4274.01 6.486666667 6.926666667 0.094683944 Up 0.190548723 Nod1 nucleotide-binding oligomerization domain containing 1 K08727|1|0.0|1784|mmu:107607|nucleotide-binding oligomerization domain-containing protein 1 GO:0044424;GO:0044459;GO:0044424;GO:0044459 GO:0032550;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding GO:0032872//regulation of stress-activated MAPK cascade;GO:0032637//interleukin-8 production;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002468//dendritic cell antigen processing and presentation;GO:0042742//defense response to bacterium;GO:0006915//apoptotic process;GO:0007254//JNK cascade;GO:0001819//positive regulation of cytokine production;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0012502//induction of programmed cell death;GO:0043410//positive regulation of MAPK cascade;GO:0009581;GO:0032872//regulation of stress-activated MAPK cascade;GO:0032637//interleukin-8 production;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002468//dendritic cell antigen processing and presentation;GO:0042742//defense response to bacterium;GO:0006915//apoptotic process;GO:0007254//JNK cascade;GO:0001819//positive regulation of cytokine production;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0012502//induction of programmed cell death;GO:0043410//positive regulation of MAPK cascade;GO:0009581 gi|33563305|ref|NP_766317.1|/0/nucleotide-binding oligomerization domain-containing protein 1 [Mus musculus] 106947 3479 7.266666667 6.826666667 -0.09011242 Down 0.190548723 Slc39a3 "solute carrier family 39 (zinc transporter), member 3" "K14709|1|5e-137|491|mmu:106947|solute carrier family 39 (zinc transporter), member 1/2/3" GO:0031224//intrinsic component of membrane GO:0046915//transition metal ion transmembrane transporter activity GO:0006829//zinc II ion transport;GO:0044763 "gi|148699520|gb|EDL31467.1|/3.46257e-156/solute carrier family 39 (zinc transporter), member 3, isoform CRA_a [Mus musculus]" 105246506 2708 7.286666667 7.73 0.085209419 Up 0.190548723 LOC105246506 uncharacterized LOC105246506 - - - - - 234549 3190 10.10333333 9.56 -0.079748828 Down 0.190501711 Heatr3 HEAT repeat containing 3 - - - - "gi|148679105|gb|EDL11052.1|/0/HEAT repeat containing 3, isoform CRA_b, partial [Mus musculus]" 233276 3681 1.963333333 1.746666667 -0.168700822 Down 0.190435895 Tubgcp5 "tubulin, gamma complex associated protein 5" K16572|1|0.0|2002|mmu:233276|gamma-tubulin complex component 5 GO:0000931//gamma-tubulin large complex;GO:0005819//spindle GO:0015631//tubulin binding GO:0000226//microtubule cytoskeleton organization gi|46560557|ref|NP_666302.2|/0/gamma-tubulin complex component 5 [Mus musculus] 101490 4740 2.03 1.81 -0.16549003 Down 0.190435895 Inpp5f inositol polyphosphate-5-phosphatase F K20279|1|5e-46|189|acs:100567389|synaptojanin [EC:3.1.3.36] - "GO:0016788//hydrolase activity, acting on ester bonds" GO:0048017//inositol lipid-mediated signaling;GO:0046475//glycerophospholipid catabolic process;GO:0003299 gi|37360162|dbj|BAC98059.1|/0/mKIAA0966 protein [Mus musculus] 211978 9368 1.91 1.693333333 -0.173706642 Down 0.190435895 Zfyve26 "zinc finger, FYVE domain containing 26" K19027|1|0.0|4497|mmu:211978|zinc finger FYVE domain-containing protein 26 GO:0005815//microtubule organizing center GO:1901981//phosphatidylinositol phosphate binding;GO:0043169//cation binding GO:0000725//recombinational repair gi|60360314|dbj|BAD90401.1|/0/mKIAA0321 protein [Mus musculus] 230119 4360 2.036666667 1.813333333 -0.167565729 Down 0.190435895 Zbtb5 zinc finger and BTB domain containing 5 K10492|1|0.0|1161|mmu:230119|zinc finger and BTB domain-containing protein 5 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|37359912|dbj|BAC97934.1|/0/mKIAA0354 protein [Mus musculus] 74453 1876 0.03 0.106666667 1.830074999 Up 0.190398285 Cfap53 cilia and flagella associated protein 53 K11589|1|1e-139|499|chx:102168507|methyl-CpG-binding domain protein 1;K16811|3|1e-07|60.8|sko:100377118|trichoplein keratin filament-binding protein;K16476|5|1e-06|57.8|phi:102113078|ninein - - - gi|261862311|ref|NP_083224.2|/0/cilia- and flagella-associated protein 53 [Mus musculus] 72184 1958 0.033333333 0.116666667 1.807354922 Up 0.190398285 Klhl35 kelch-like 35 K10461|1|0.0|979|mmu:72184|kelch-like protein 24/35 - - - gi|259013526|ref|NP_082421.1|/0/kelch-like protein 35 [Mus musculus] 627427 1903 0.03 0.106666667 1.830074999 Up 0.190398285 Gm6756 3-phosphoglycerate dehydrogenase pseudogene K00058|1|0.0|895|mmu:236539|D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95] GO:0044444//cytoplasmic part "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding" GO:0007417//central nervous system development;GO:0007049//cell cycle;GO:0030030//cell projection organization;GO:0006790//sulfur compound metabolic process;GO:0009064//glutamine family amino acid metabolic process;GO:0010001//glial cell differentiation;GO:0008652//cellular amino acid biosynthetic process;GO:0006563//L-serine metabolic process;GO:0010467//gene expression;GO:0009066 gi|52353955|ref|NP_058662.2|/0/D-3-phosphoglycerate dehydrogenase [Mus musculus] 67141 1820 1.45 1.256666667 -0.206450877 Down 0.190360675 Fbxo5 F-box protein 5 K10292|1|0.0|856|mmu:67141|F-box protein 5 GO:0031981//nuclear lumen;GO:0015630//microtubule cytoskeleton GO:0046914//transition metal ion binding;GO:0019900//kinase binding GO:0007127//meiosis I;GO:0003006//developmental process involved in reproduction;GO:0007056//spindle assembly involved in female meiosis;GO:0031109//microtubule polymerization or depolymerization;GO:0051440 gi|110225374|ref|NP_080271.2|/0/F-box only protein 5 [Mus musculus] 239364 4040 1.213333333 1.406666667 0.213304549 Up 0.190360675 Tspyl5 "testis-specific protein, Y-encoded-like 5" K11288|1|0.0|660|mmu:239364|TSPY-like 5 - - - gi|50511091|dbj|BAD32531.1|/0/mKIAA1750 protein [Mus musculus] 20419 2244 0.22 0.12 -0.874469118 Down 0.190313664 Shcbp1 Shc SH2-domain binding protein 1 - - GO:0019904//protein domain specific binding GO:0042127//regulation of cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|6755508|ref|NP_035499.1|/0/SHC SH2 domain-binding protein 1 [Mus musculus] 654470 4010 2.376666667 2.14 -0.151328779 Down 0.190285456 Tctn1 tectonic family member 1 K19382|1|0.0|1123|mmu:654470|tectonic-1/3 GO:0035869//ciliary transition zone;GO:0043232;GO:0044421;GO:0035869//ciliary transition zone;GO:0043232;GO:0044421 GO:0005488//binding;GO:0005488//binding GO:0007224//smoothened signaling pathway;GO:0030900//forebrain development;GO:0009953//dorsal/ventral pattern formation;GO:0001838//embryonic epithelial tube formation;GO:0021522//spinal cord motor neuron differentiation;GO:0021955//central nervous system neuron axonogenesis;GO:0007224//smoothened signaling pathway;GO:0030900//forebrain development;GO:0009953//dorsal/ventral pattern formation;GO:0001838//embryonic epithelial tube formation;GO:0021522//spinal cord motor neuron differentiation;GO:0021955//central nervous system neuron axonogenesis gi|109809735|ref|NP_001034242.2|/0/tectonic-1 precursor [Mus musculus] 100041574 2120 2.436666667 2.196666667 -0.149592941 Down 0.190285456 9030025P20Rik RIKEN cDNA 9030025P20 gene - - - - gi|183074533|ref|NP_001116842.1|/0/uncharacterized protein LOC100041574 [Mus musculus] 320541 6333 2.15 2.386666667 0.150660427 Up 0.190285456 Slc35e2 "solute carrier family 35, member E2" "K15284|1|0.0|716|mmu:320541|solute carrier family 35, member E2" GO:0031224//intrinsic component of membrane - - gi|28893193|ref|NP_796160.1|/0/solute carrier family 35 member E2 [Mus musculus] 13498 4426 40.62333333 39.06666667 -0.05637046 Down 0.190266652 Atn1 atrophin 1 K05626|1|0.0|1175|mmu:13498|atrophin-1 (dentatorubral-pallidoluysian atrophy protein) GO:0043231//intracellular membrane-bounded organelle GO:0005102//receptor binding;GO:0003712//transcription cofactor activity GO:0007163//establishment or maintenance of cell polarity;GO:0044237//cellular metabolic process;GO:0019748//secondary metabolic process;GO:0048870//cell motility gi|34328110|ref|NP_031907.2|/0/atrophin-1 [Mus musculus] 54325 1826 15.35333333 16.11666667 0.070001479 Up 0.190238444 Elovl1 "elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1" K10247|1|9e-175|575|cge:100767465|elongation of very long chain fatty acids protein 1 [EC:2.3.1.199] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004312//fatty acid synthase activity;GO:0004312//fatty acid synthase activity;GO:0004312//fatty acid synthase activity "GO:0019368//fatty acid elongation, unsaturated fatty acid;GO:0000038//very long-chain fatty acid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0019368//fatty acid elongation, unsaturated fatty acid;GO:0000038//very long-chain fatty acid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0019368//fatty acid elongation, unsaturated fatty acid;GO:0000038//very long-chain fatty acid metabolic process;GO:0006665//sphingolipid metabolic process" "gi|148698556|gb|EDL30503.1|/3.04431e-119/elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1, isoform CRA_a, partial [Mus musculus]" 57314 2279 14.57333333 15.33 0.073026797 Up 0.190238444 Nelfcd "negative elongation factor complex member C/D, Th1l" K15181|1|0.0|1090|mmu:57314|negative elongation factor C/D GO:0008023//transcription elongation factor complex - "GO:0006351//transcription, DNA-templated" gi|91982765|ref|NP_065605.2|/0/negative elongation factor D [Mus musculus] 53317 1771 15.51666667 14.76 -0.072125946 Down 0.190238444 Plrg1 pleiotropic regulator 1 K12862|1|0.0|1056|mmu:53317|pleiotropic regulator 1 - - - - 27027 1511 0.296666667 0.42 0.501546493 Up 0.190229042 Tspan32 tetraspanin 32 K17359|1|1e-121|439|rno:365390|tetraspanin-32 GO:0008305//integrin complex;GO:0008305//integrin complex;GO:0008305//integrin complex;GO:0008305//integrin complex - GO:0030168//platelet activation;GO:0006996//organelle organization;GO:0001562//response to protozoan;GO:0001773//myeloid dendritic cell activation;GO:0007166//cell surface receptor signaling pathway;GO:0002697;GO:0008283//cell proliferation;GO:0030168//platelet activation;GO:0006996//organelle organization;GO:0001562//response to protozoan;GO:0001773//myeloid dendritic cell activation;GO:0007166//cell surface receptor signaling pathway;GO:0002697;GO:0008283//cell proliferation;GO:0030168//platelet activation;GO:0006996//organelle organization;GO:0001562//response to protozoan;GO:0001773//myeloid dendritic cell activation;GO:0007166//cell surface receptor signaling pathway;GO:0002697;GO:0008283//cell proliferation;GO:0030168//platelet activation;GO:0006996//organelle organization;GO:0001562//response to protozoan;GO:0001773//myeloid dendritic cell activation;GO:0007166//cell surface receptor signaling pathway;GO:0002697;GO:0008283//cell proliferation gi|189339194|ref|NP_001121552.1|/1.37981e-122/tetraspanin-32 isoform a [Mus musculus] 68918 752 1.113333333 0.94 -0.24415294 Down 0.19021964 1190005I06Rik RIKEN cDNA 1190005I06 gene K10733|1|3e-08|60.8|asn:102385759|GINS complex subunit 2 - - - gi|261245127|ref|NP_932105.2|/3.64678e-41/uncharacterized protein C16orf74 homolog [Mus musculus] 194219 1762 0.113333333 0.033333333 -1.765534746 Down 0.190210237 Slfnl1 schlafen like 1 - - GO:0032550 - gi|29243912|ref|NP_808238.1|/3.52027e-177/schlafen-like protein 1 [Mus musculus] 319812 4095 0.176666667 0.083333333 -1.084064265 Down 0.190135018 9430018G01Rik RIKEN cDNA 9430018G01 gene - - - - - 12532 1945 0.176666667 0.083333333 -1.084064265 Down 0.190135018 Cdc25c cell division cycle 25C K05867|1|0.0|881|mmu:12532|M-phase inducer phosphatase 3 [EC:3.1.3.48] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0004721//phosphoprotein phosphatase activity;GO:0019904//protein domain specific binding;GO:0019900//kinase binding GO:0006464//cellular protein modification process;GO:0000087//mitotic M phase gi|122114545|ref|NP_033990.2|/0/M-phase inducer phosphatase 3 [Mus musculus] 271970 3690 0.093333333 0.186666667 1 Up 0.190135018 Arsj arylsulfatase J K12375|1|0.0|1174|mmu:271970|arylsulfatase I/J [EC:3.1.6.-] - "GO:0016788//hydrolase activity, acting on ester bonds;GO:0043169//cation binding" - gi|27734088|ref|NP_775627.1|/0/arylsulfatase J precursor [Mus musculus] 71962 1570 5.263333333 5.633333333 0.098012075 Up 0.190106811 Gatsl3 GATS protein-like 3 K19944|1|4e-122|441|gfr:102042531|TBC1 domain family member 10 - - - gi|58037269|ref|NP_082298.1|/0/GATS-like protein 3 [Mus musculus] 19291 8478 5.666666667 5.293333333 -0.098323834 Down 0.190106811 Purb purine rich element binding protein B K11838|1|4e-65|254|chx:102188997|ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12];K10356|2|2e-32|145|myd:102759127|myosin I;K13696|4|3e-06|58.5|hro:HELRODRAFT_182167|abhydrolase domain-containing protein 1/3 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003723//RNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0043566//structure-specific DNA binding "GO:0012501//programmed cell death;GO:0048869//cellular developmental process;GO:0002682//regulation of immune system process;GO:0006351//transcription, DNA-templated" gi|6755252|ref|NP_035351.1|/8.28105e-109/transcriptional activator protein Pur-beta [Mus musculus] 77634 1413 5.693333333 5.326666667 -0.096040567 Down 0.190106811 Snapc3 "small nuclear RNA activating complex, polypeptide 3" K15210|1|0.0|864|mmu:77634|snRNA-activating protein complex subunit 3 GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated" "gi|148699079|gb|EDL31026.1|/0/small nuclear RNA activating complex, polypeptide 3, isoform CRA_c, partial [Mus musculus]" 77827 7005 5.38 5.01 -0.102795569 Down 0.190106811 Krba1 KRAB-A domain containing 1 K09228|1|9e-10|70.1|pss:102447281|KRAB domain-containing zinc finger protein - - - "gi|148666108|gb|EDK98524.1|/0/RIKEN cDNA A930040G15, isoform CRA_b, partial [Mus musculus]" 56207 1849.97 4.906666667 5.273333333 0.103971928 Up 0.190106811 Uchl5 ubiquitin carboxyl-terminal esterase L5 K05610|1|9e-176|619|mmu:56207|ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12] GO:0000790//nuclear chromatin;GO:0044444//cytoplasmic part GO:0061135;GO:0008238//exopeptidase activity;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0032403//protein complex binding "GO:0009653//anatomical structure morphogenesis;GO:0006351//transcription, DNA-templated;GO:0010498//proteasomal protein catabolic process;GO:0006259//DNA metabolic process;GO:0019941//modification-dependent protein catabolic process;GO:0033554//cellular response to stress;GO:0070646//protein modification by small protein removal;GO:0021537//telencephalon development;GO:0010466//negative regulation of peptidase activity" "gi|148707562|gb|EDL39509.1|/0/ubiquitin carboxyl-terminal esterase L5, isoform CRA_b, partial [Mus musculus]" 269630 2546 3.356666667 3.66 0.124814371 Up 0.190069202 5031425E22Rik RIKEN cDNA 5031425E22 gene - - - - - 103710 3059 3.433333333 3.733333333 0.120854395 Up 0.190069202 Slc35e4 "solute carrier family 35, member E4" "K15286|1|1e-172|610|mmu:103710|solute carrier family 35, member E4" GO:0031224//intrinsic component of membrane - - "gi|148708499|gb|EDL40446.1|/0/solute carrier family 35, member E4, isoform CRA_b, partial [Mus musculus]" 19725 3278 2.17 1.94 -0.16163839 Down 0.190059799 Rfx2 "regulatory factor X, 2 (influences HLA class II expression)" K09173|1|0.0|1370|mmu:19725|regulatory factor X 1/2/3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|226958468|ref|NP_082063.1|/0/DNA-binding protein RFX2 isoform 1 [Mus musculus] 69131 7309.2 2.19 1.956666667 -0.162532867 Down 0.190059799 Cdk12 cyclin-dependent kinase 12 K08819|1|0.0|1885|mmu:69131|cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23] GO:0016604//nuclear body;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0016604//nuclear body;GO:0000307//cyclin-dependent protein kinase holoenzyme complex GO:0032550;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043408//regulation of MAPK cascade;GO:0006396//RNA processing;GO:0006468//protein phosphorylation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043408//regulation of MAPK cascade;GO:0006396//RNA processing;GO:0006468//protein phosphorylation gi|157816961|ref|NP_001103098.1|/0/cyclin-dependent kinase 12 isoform 2 [Mus musculus] 15979 2126 37.9 39.43 0.057095862 Up 0.190012787 Ifngr1 interferon gamma receptor 1 K05132|1|0.0|927|mmu:15979|interferon gamma receptor 1 - - - - 73689 910 9.896666667 9.366666667 -0.079406963 Down 0.18998458 Bloc1s2 "biogenesis of lysosomal organelles complex-1, subunit 2" K16750|1|4e-51|203|mmu:73689|biogenesis of lysosome-related organelles complex 1 subunit 2 - - - - 107568 6458 10.19666667 9.663333333 -0.077504773 Down 0.18998458 Wwp1 WW domain containing E3 ubiquitin protein ligase 1 K05633|1|0.0|1782|mmu:107568|atrophin-1 interacting protein 5 (WW domain containing E3 ubiquitin protein ligase 1) [EC:2.3.2.26] - - - gi|67078498|ref|NP_001019928.1|/0/NEDD4-like E3 ubiquitin-protein ligase WWP1 [Rattus norvegicus] 20963 5144.87 10.22 9.69 -0.076826626 Down 0.18998458 Syk spleen tyrosine kinase K05855|1|0.0|1307|mmu:20963|spleen tyrosine kinase [EC:2.7.10.2] GO:0045335//phagocytic vesicle;GO:0043235//receptor complex;GO:0019814;GO:0016020//membrane;GO:0045335//phagocytic vesicle;GO:0043235//receptor complex;GO:0019814;GO:0016020//membrane GO:0004713//protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0032550 GO:0045058//T cell selection;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0033627//cell adhesion mediated by integrin;GO:0010543//regulation of platelet activation;GO:0032846;GO:0050851//antigen receptor-mediated signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0042554//superoxide anion generation;GO:0050663//cytokine secretion;GO:0032303;GO:0002238//response to molecule of fungal origin;GO:0030595//leukocyte chemotaxis;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0045582//positive regulation of T cell differentiation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0042492//gamma-delta T cell differentiation;GO:0030183//B cell differentiation;GO:0019722//calcium-mediated signaling;GO:0000187//activation of MAPK activity;GO:0002442;GO:0033008;GO:0001568//blood vessel development;GO:0006909//phagocytosis;GO:0042102//positive regulation of T cell proliferation;GO:0045058//T cell selection;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0033627//cell adhesion mediated by integrin;GO:0010543//regulation of platelet activation;GO:0032846;GO:0050851//antigen receptor-mediated signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0042554//superoxide anion generation;GO:0050663//cytokine secretion;GO:0032303;GO:0002238//response to molecule of fungal origin;GO:0030595//leukocyte chemotaxis;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0045582//positive regulation of T cell differentiation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0042492//gamma-delta T cell differentiation;GO:0030183//B cell differentiation;GO:0019722//calcium-mediated signaling;GO:0000187//activation of MAPK activity;GO:0002442;GO:0033008;GO:0001568//blood vessel development;GO:0006909//phagocytosis;GO:0042102//positive regulation of T cell proliferation gi|56550045|ref|NP_035648.2|/0/tyrosine-protein kinase SYK [Mus musculus] 66844 2055 9.836666667 10.37 0.076174474 Up 0.18998458 Ormdl2 ORM1-like 2 (S. cerevisiae) K12667|1|1e-34|150|smm:Smp_144800|oligosaccharyltransferase complex subunit delta (ribophorin II) GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0006665//sphingolipid metabolic process gi|594662831|ref|XP_007179600.1|/4.79831e-83/PREDICTED: ORM1-like protein 2 isoform X1 [Balaenoptera acutorostrata scammoni] 211770 4026 8.99 9.52 0.082640458 Up 0.18998458 Trib1 tribbles pseudokinase 1 K08814|1|0.0|637|mmu:211770|tribbles homolog 1/2 GO:0043231//intracellular membrane-bounded organelle GO:0016301//kinase activity;GO:0032550;GO:0044389//ubiquitin-like protein ligase binding;GO:0019901//protein kinase binding;GO:0055103//ligase regulator activity;GO:0019887//protein kinase regulator activity GO:0014909//smooth muscle cell migration;GO:0002832;GO:0031398//positive regulation of protein ubiquitination;GO:0043408//regulation of MAPK cascade;GO:0008285//negative regulation of cell proliferation;GO:0001933//negative regulation of protein phosphorylation;GO:0044092//negative regulation of molecular function;GO:0031331;GO:0002237//response to molecule of bacterial origin;GO:0051403//stress-activated MAPK cascade gi|21362355|ref|NP_653132.1|/5.28503e-180/tribbles homolog 1 [Mus musculus] 56289 1733.52 8.943333333 9.473333333 0.0830595 Up 0.18998458 Rassf1 Ras association (RalGDS/AF-6) domain family member 1 K09850|1|4e-140|473|mcc:702385|Ras association domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane GO:0043169//cation binding;GO:0005515//protein binding;GO:0043169//cation binding;GO:0005515//protein binding GO:0007050//cell cycle arrest;GO:0007264//small GTPase mediated signal transduction;GO:0033554//cellular response to stress;GO:0031647//regulation of protein stability;GO:0016567//protein ubiquitination;GO:0007050//cell cycle arrest;GO:0007264//small GTPase mediated signal transduction;GO:0033554//cellular response to stress;GO:0031647//regulation of protein stability;GO:0016567//protein ubiquitination gi|344217757|ref|NP_001230677.1|/0/ras association domain-containing protein 1 isoform 1 [Mus musculus] 93725 471 0.116666667 0.036666667 -1.669851398 Down 0.189956373 Ear10 "eosinophil-associated, ribonuclease A family, member 10" K10787|1|7e-43|174|rno:100361866|eosinophil cationic protein [EC:3.1.27.-];K01168|2|1e-41|170|rno:474169|pancreatic ribonuclease [EC:3.1.27.5] GO:0044424 "GO:0016892//endoribonuclease activity, producing 3'-phosphomonoesters;GO:0097159//organic cyclic compound binding" GO:0042221//response to chemical "gi|21426867|ref|NP_444342.1|/4.3317e-78/eosinophil-associated, ribonuclease A family, member 10 precursor [Mus musculus]" 22446 1584 0.04 0.12 1.584962501 Up 0.189956373 Xlr3c X-linked lymphocyte-regulated 3C K19528|1|1e-20|103|mmu:20962|synaptonemal complex protein 3 - - - gi|154091005|ref|NP_035857.2|/5.29712e-121/X-linked lymphocyte-regulated protein 3C [Mus musculus] 66400 939 34.63333333 33.11333333 -0.064749002 Down 0.189956373 Alkbh7 alkB homolog 7 K10769|1|3e-105|384|mmu:66400|alkylated DNA repair protein alkB homolog 7 [EC:1.14.11.-] - - - - 100038947 1456 0.04 0.123333333 1.624490865 Up 0.189956373 LOC100038947 signal-regulatory protein beta 1-like K06551|1|0.0|705|mmu:100038947|signal-regulatory protein alpha/beta1/gamma GO:0016020//membrane - GO:0006909//phagocytosis;GO:0007165//signal transduction gi|291045296|ref|NP_001166930.1|/0/signal-regulatory protein beta 1-like precursor [Mus musculus] 100042679 4221 0.036666667 0.113333333 1.628031223 Up 0.189956373 Gm16386 zinc finger protein 946 pseudogene K09228|1|0.0|730|rno:690559|KRAB domain-containing zinc finger protein - - - "gi|149047034|gb|EDL99754.1|/0/rCG64318, partial [Rattus norvegicus]" 18749 4320.73 15.96333333 15.21 -0.069741782 Down 0.189956373 Prkacb "protein kinase, cAMP dependent, catalytic, beta" K04345|1|0.0|717|rno:293508|protein kinase A [EC:2.7.11.11] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0051018//protein kinase A binding;GO:0032550;GO:0046872//metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0051018//protein kinase A binding;GO:0032550;GO:0046872//metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0051018//protein kinase A binding;GO:0032550;GO:0046872//metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0051018//protein kinase A binding;GO:0032550;GO:0046872//metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0004690//cyclic nucleotide-dependent protein kinase activity "GO:0010243//response to organonitrogen compound;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0045786//negative regulation of cell cycle;GO:0010243//response to organonitrogen compound;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0045786//negative regulation of cell cycle;GO:0010243//response to organonitrogen compound;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0045786//negative regulation of cell cycle;GO:0010243//response to organonitrogen compound;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0045786//negative regulation of cell cycle" gi|6755076|ref|NP_035230.1|/0/cAMP-dependent protein kinase catalytic subunit beta isoform 1 [Mus musculus] 67855 1550 0.036666667 0.113333333 1.628031223 Up 0.189956373 Asprv1 "aspartic peptidase, retroviral-like 1" - GO:0031224//intrinsic component of membrane GO:0004175//endopeptidase activity GO:0051604//protein maturation;GO:0008544//epidermis development gi|130502130|ref|NP_080690.2|/4.89058e-180/retroviral-like aspartic protease 1 [Mus musculus] 234788 2648 0.116666667 0.036666667 -1.669851398 Down 0.189956373 Slc38a8 "solute carrier family 38, member 8" "K14994|1|0.0|802|mmu:234788|solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 7/8" - - - - 100316717 73 1.3 1.12 -0.215012891 Down 0.189871751 Mir1839 microRNA 1839 - - - - - 381629 966.1 38.40333333 39.91666667 0.055759711 Up 0.189852947 Atraid all-trans retinoic acid induced differentiation factor "K14386|1|1e-33|145|aam:106495620|solute carrier family 5 (sodium-dependent multivitamin transporter), member 6" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system - GO:0008054//negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation;GO:0008285//negative regulation of cell proliferation;GO:0030282//bone mineralization;GO:0001649//osteoblast differentiation;GO:0010467//gene expression;GO:0008054//negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation;GO:0008285//negative regulation of cell proliferation;GO:0030282//bone mineralization;GO:0001649//osteoblast differentiation;GO:0010467//gene expression gi|47087146|ref|NP_082131.2|/1.04354e-95/all-trans retinoic acid-induced differentiation factor isoform 1 precursor [Mus musculus] 12983 4776 0.546666667 0.69 0.335934953 Up 0.189777728 Csf2rb "colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)" K04738|1|0.0|1665|mmu:12983|cytokine receptor common subunit beta GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0002237//response to molecule of bacterial origin;GO:0007166//cell surface receptor signaling pathway "gi|86577678|gb|AAI13203.1|/0/Colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) [Mus musculus]" 320782 3342 0.51 0.646666667 0.342524999 Up 0.189777728 Tmem154 transmembrane protein 154 - GO:0016020//membrane - - gi|625286109|ref|XP_007634776.1|/2.97374e-72/PREDICTED: transmembrane protein 154 isoform X2 [Cricetulus griseus] 22634 5279 0.523333333 0.663333333 0.342003872 Up 0.189777728 Plagl1 pleiomorphic adenoma gene-like 1 K19485|1|3e-163|579|mmu:22634|zinc finger protein PLAGL1 - - - gi|12060990|gb|AAG48331.1|/2.68598e-167/lost on transformation protein 1 [Mus musculus] 20739 8405 0.67 0.53 -0.338168736 Down 0.189777728 Spta1 "spectrin alpha, erythrocytic 1" K06114|1|0.0|4471|mmu:20739|spectrin alpha GO:0030864//cortical actin cytoskeleton GO:0046983//protein dimerization activity;GO:0008092//cytoskeletal protein binding;GO:0046872//metal ion binding GO:0022604//regulation of cell morphogenesis;GO:0030835//negative regulation of actin filament depolymerization;GO:0043393//regulation of protein binding;GO:0006778//porphyrin-containing compound metabolic process;GO:0048534//hematopoietic or lymphoid organ development;GO:0042098//T cell proliferation "gi|19526481|ref|NP_035595.2|/0/spectrin alpha chain, erythrocytic 1 [Mus musculus]" 244871 6133 0.42 0.3 -0.485426827 Down 0.189777728 Zc3h12c zinc finger CCCH type containing 12C K18668|1|0.0|1680|mmu:244871|ribonuclease ZC3H12 [EC:3.1.-.-] - - - - 50523 5213 7.24 6.81 -0.088334899 Down 0.189646094 Lats2 large tumor suppressor 2 K08791|1|3e-57|224|mmu:50523|serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle GO:0032550;GO:0004672//protein kinase activity;GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity;GO:0043169//cation binding GO:0044772//mitotic cell cycle phase transition;GO:0035265//organ growth;GO:0009913//epidermal cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0008104//protein localization;GO:0000087//mitotic M phase;GO:0035556//intracellular signal transduction;GO:0044772//mitotic cell cycle phase transition;GO:0035265//organ growth;GO:0009913//epidermal cell differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0008104//protein localization;GO:0000087//mitotic M phase;GO:0035556//intracellular signal transduction gi|218777832|ref|NP_700431.1|/2.84255e-95/serine/threonine-protein kinase LATS2 isoform 2 [Mus musculus] 14007 7852.45 6.966666667 7.4 0.087056734 Up 0.189646094 Celf2 "CUGBP, Elav-like family member 2" K13207|1|0.0|647|hgl:101700202|CUG-BP- and ETR3-like factor - - - gi|918594517|ref|XP_013369151.1|/0/PREDICTED: CUGBP Elav-like family member 2 isoform X6 [Chinchilla lanigera] 384724 1512 0.223333333 0.123333333 -0.856635825 Down 0.189580278 Cyp2t4 "cytochrome P450, family 2, subfamily t, polypeptide 4" "K07421|1|0.0|942|mmu:384724|cytochrome P450, family 2, subfamily T" - GO:0016491//oxidoreductase activity;GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding - "gi|154146204|ref|NP_001093654.1|/0/cytochrome P450, family 2, subfamily t, polypeptide 4 [Mus musculus]" 54710 6004 0.123333333 0.223333333 0.856635825 Up 0.189580278 Hs3st3b1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 K07809|1|0.0|721|mmu:54710|[heparan sulfate]-glucosamine 3-sulfotransferase 3 [EC:2.8.2.30] GO:0016021//integral component of membrane;GO:0012505//endomembrane system GO:0034483//heparan sulfate sulfotransferase activity GO:0006464//cellular protein modification process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0006023 gi|84370343|ref|NP_061275.2|/0/heparan sulfate glucosamine 3-O-sulfotransferase 3B1 [Mus musculus] 237038 2563 0.23 0.126666667 -0.860596943 Down 0.189580278 Nox1 NADPH oxidase 1 K08008|1|0.0|1101|mmu:237038|NADPH oxidase GO:0031253//cell projection membrane;GO:0005768//endosome;GO:0005887//integral component of plasma membrane "GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor;GO:0043169//cation binding;GO:0017048//Rho GTPase binding;GO:0015252//hydrogen ion channel activity" GO:0006818//hydrogen transport;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0001990//regulation of systemic arterial blood pressure by hormone;GO:0006091//generation of precursor metabolites and energy;GO:0048870//cell motility;GO:0007154//cell communication;GO:0001819//positive regulation of cytokine production;GO:0008284//positive regulation of cell proliferation;GO:0044710;GO:0009628//response to abiotic stimulus;GO:0006801//superoxide metabolic process;GO:0045852;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0043062//extracellular structure organization gi|284018105|sp|Q8CIZ9.2|NOX1_MOUSE/0/RecName: Full=NADPH oxidase 1; Short=NOX-1 269682 4833 14.95666667 14.22 -0.072867218 Down 0.189486254 Golga3 "golgi autoantigen, golgin subfamily a, 3" K20283|1|5e-36|156|mde:101892550|golgin subfamily A member 4 GO:0012505//endomembrane system;GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0005488//binding GO:0048232//male gamete generation;GO:0048869//cellular developmental process "gi|148688087|gb|EDL20034.1|/0/golgi autoantigen, golgin subfamily a, 3, isoform CRA_b, partial [Mus musculus]" 56228 3522 15.29333333 14.55666667 -0.07122286 Down 0.189486254 Ube2j1 ubiquitin-conjugating enzyme E2J 1 K10578|1|6e-156|554|mmu:56228|ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0019787//ubiquitin-like protein transferase activity GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation;GO:0006487//protein N-linked glycosylation gi|31980960|ref|NP_062532.2|/5.06959e-155/ubiquitin-conjugating enzyme E2 J1 [Mus musculus] 231329 3812 15.59 14.84666667 -0.070481871 Down 0.189486254 Polr2b polymerase (RNA) II (DNA directed) polypeptide B K03010|1|0.0|2275|mmu:231329|DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] "GO:0016591//DNA-directed RNA polymerase II, holoenzyme" GO:0016301//kinase activity;GO:0003676//nucleic acid binding;GO:0043169//cation binding;GO:0034062//RNA polymerase activity;GO:0001882//nucleoside binding GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006397//mRNA processing;GO:0044764;GO:0006289//nucleotide-excision repair;GO:0000377;GO:0006464//cellular protein modification process gi|23512288|gb|AAH38472.1|/0/Polymerase (RNA) II (DNA directed) polypeptide B [Mus musculus] 68201 2097 1.81 1.6 -0.177917792 Down 0.189401632 Ccdc34 coiled-coil domain containing 34 K16753|1|4e-89|331|mmu:68201|coiled-coil domain-containing protein 34 - - - gi|205361118|ref|NP_080889.3|/3.81963e-88/coiled-coil domain-containing protein 34 [Mus musculus] 68842 8900.34 4.486666667 4.16 -0.109060476 Down 0.189401632 Tulp4 tubby like protein 4 K19674|1|8e-33|147|gja:107114264|WD repeat-containing protein 35 - - GO:0007165//signal transduction;GO:0007165//signal transduction gi|16905077|ref|NP_473381.1|/0/tubby-related protein 4 isoform a [Mus musculus] 140795 1855.7 4.37 4.7 0.105027477 Up 0.189401632 P2ry14 "purinergic receptor P2Y, G-protein coupled, 14" "K04299|1|0.0|648|mmu:140795|purinergic receptor P2Y, G protein-coupled, 14" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0015065//uridine nucleotide receptor activity;GO:0015065//uridine nucleotide receptor activity;GO:0015065//uridine nucleotide receptor activity;GO:0015065//uridine nucleotide receptor activity;GO:0015065//uridine nucleotide receptor activity;GO:0015065//uridine nucleotide receptor activity;GO:0015065//uridine nucleotide receptor activity;GO:0015065//uridine nucleotide receptor activity GO:0035588;GO:0002376//immune system process;GO:0035588;GO:0002376//immune system process;GO:0035588;GO:0002376//immune system process;GO:0035588;GO:0002376//immune system process;GO:0035588;GO:0002376//immune system process;GO:0035588;GO:0002376//immune system process;GO:0035588;GO:0002376//immune system process;GO:0035588;GO:0002376//immune system process gi|560879477|ref|NP_001274053.1|/0/P2Y purinoceptor 14 isoform b [Mus musculus] 73825 3151 4.06 4.386666667 0.111645356 Up 0.189401632 Ppp1r21 "protein phosphatase 1, regulatory subunit 21" K17562|1|0.0|1396|mmu:73825|protein phosphatase 1 regulatory subunit 21 - GO:0019899//enzyme binding - gi|254911014|ref|NP_082934.3|/0/protein phosphatase 1 regulatory subunit 21 [Mus musculus] 333193 2612 1.856666667 1.643333333 -0.176089681 Down 0.189401632 Proser3 proline and serine rich 3 K17933|1|3e-18|96.7|mdo:100617737|Rho GTPase-activating protein 33 - - - gi|568946055|ref|XP_006540186.1|/0/PREDICTED: proline and serine-rich protein 3 isoform X2 [Mus musculus] 54140 2671 0.42 0.553333333 0.397759508 Up 0.189326413 Avpr1a arginine vasopressin receptor 1A K04226|1|0.0|821|mmu:54140|arginine vasopressin receptor 1A GO:0031224//intrinsic component of membrane;GO:0012506//vesicle membrane GO:0008528//G-protein coupled peptide receptor activity;GO:0042277//peptide binding;GO:0031893 GO:0002027//regulation of heart rate;GO:0009414//response to water deprivation;GO:0019229//regulation of vasoconstriction;GO:0032846;GO:0035809;GO:0019932//second-messenger-mediated signaling;GO:0051384//response to glucocorticoid;GO:0060746//parental behavior;GO:0035914//skeletal muscle cell differentiation;GO:0030900//forebrain development;GO:0016049//cell growth;GO:0035813//regulation of renal sodium excretion;GO:0044060//regulation of endocrine process;GO:0014047//glutamate secretion;GO:0001516//prostaglandin biosynthetic process;GO:0044708//single-organism behavior;GO:0007166//cell surface receptor signaling pathway;GO:0001990//regulation of systemic arterial blood pressure by hormone;GO:0002118//aggressive behavior;GO:0008283//cell proliferation;GO:0010648;GO:0005980//glycogen catabolic process;GO:0045924//regulation of female receptivity;GO:0007320//insemination;GO:0051480//regulation of cytosolic calcium ion concentration gi|33149329|ref|NP_058543.2|/0/vasopressin V1a receptor [Mus musculus] 229644 3768.52 1.646666667 1.446666667 -0.186815999 Down 0.189326413 Trim45 tripartite motif-containing 45 K12021|1|0.0|1128|mmu:229644|tripartite motif-containing protein 45 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0001501//skeletal system development;GO:0001501//skeletal system development;GO:0001501//skeletal system development gi|260099706|ref|NP_001159425.1|/0/tripartite motif-containing protein 45 isoform a [Mus musculus] 71529 4212.03 1.583333333 1.386666667 -0.191343985 Down 0.189326413 Kazn "kazrin, periplakin interacting protein" K04407|1|3e-08|64.7|xtr:100491719|mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1];K17751|2|4e-07|60.8|crg:105338907|myosin heavy chain 6/7;K10421|3|7e-07|60.1|tru:101067356|CAP-Gly domain-containing linker protein 1;K10352|4|9e-07|59.7|dmo:Dmoj_GI19126|myosin heavy chain - - - - 26936 8780.23 36.02666667 34.57 -0.05954457 Down 0.189307608 Mprip myosin phosphatase Rho interacting protein K20478|1|3e-23|115|sko:100372617|golgin subfamily B member 1;K09228|3|5e-13|81.3|mcc:697042|KRAB domain-containing zinc finger protein GO:0043232;GO:0043232 GO:0008289//lipid binding;GO:0008289//lipid binding - gi|41152239|ref|NP_957697.1|/0/myosin phosphatase Rho-interacting protein isoform 1 [Mus musculus] 66711 1562 32.69 34.15 0.063036201 Up 0.189307608 Sbds Shwachman-Bodian-Diamond syndrome homolog (human) K14574|1|8e-125|449|mmu:66711|ribosome maturation protein SDO1 - - - - 74901 6996 0.65 0.796666667 0.293536494 Up 0.189298206 Kbtbd11 kelch repeat and BTB (POZ) domain containing 11 K10476|1|0.0|1071|mmu:74901|kelch repeat and BTB domain-containing protein 11 - - - gi|37360058|dbj|BAC98007.1|/0/mKIAA0711 protein [Mus musculus] 13611 2393 0.646666667 0.793333333 0.294904921 Up 0.189298206 S1pr4 sphingosine-1-phosphate receptor 4 K04293|1|3e-160|560|rno:314649|sphingosine 1-phosphate receptor 4 - - - - 19264 5249 0.686666667 0.84 0.290779396 Up 0.189298206 Ptprc "protein tyrosine phosphatase, receptor type, C" K06478|1|0.0|2163|mmu:19264|receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48] GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005924//cell-substrate adherens junction;GO:0009986//cell surface;GO:0044459;GO:0016021//integral component of membrane;GO:0005924//cell-substrate adherens junction;GO:0009986//cell surface;GO:0044459;GO:0016021//integral component of membrane;GO:0005924//cell-substrate adherens junction GO:0005539//glycosaminoglycan binding;GO:0019900//kinase binding;GO:0004721//phosphoprotein phosphatase activity;GO:0043168//anion binding;GO:0005539//glycosaminoglycan binding;GO:0019900//kinase binding;GO:0043168//anion binding;GO:0004725//protein tyrosine phosphatase activity;GO:0019207//kinase regulator activity;GO:0005539//glycosaminoglycan binding;GO:0019900//kinase binding;GO:0043168//anion binding;GO:0004725//protein tyrosine phosphatase activity;GO:0019207//kinase regulator activity GO:0048468//cell development;GO:0006915//apoptotic process;GO:0006470//protein dephosphorylation;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0043383//negative T cell selection;GO:0016337//single organismal cell-cell adhesion;GO:0001933//negative regulation of protein phosphorylation;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0045830//positive regulation of isotype switching;GO:0010212//response to ionizing radiation;GO:0002456//T cell mediated immunity;GO:0001911;GO:0030888//regulation of B cell proliferation;GO:0042492//gamma-delta T cell differentiation;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0030335//positive regulation of cell migration;GO:0043368//positive T cell selection;GO:0051283//negative regulation of sequestering of calcium ion;GO:0010564//regulation of cell cycle process;GO:0050853//B cell receptor signaling pathway;GO:0006929//substrate-dependent cell migration;GO:0000165//MAPK cascade;GO:0042102//positive regulation of T cell proliferation;GO:0048468//cell development;GO:0006915//apoptotic process;GO:0006470//protein dephosphorylation;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0043383//negative T cell selection;GO:0016337//single organismal cell-cell adhesion;GO:0001933//negative regulation of protein phosphorylation;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0045830//positive regulation of isotype switching;GO:0010212//response to ionizing radiation;GO:0002456//T cell mediated immunity;GO:0001911;GO:0030888//regulation of B cell proliferation;GO:0042492//gamma-delta T cell differentiation;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0030335//positive regulation of cell migration;GO:0043368//positive T cell selection;GO:0051283//negative regulation of sequestering of calcium ion;GO:0010564//regulation of cell cycle process;GO:0050853//B cell receptor signaling pathway;GO:0006929//substrate-dependent cell migration;GO:0000165//MAPK cascade;GO:0042102//positive regulation of T cell proliferation;GO:0048468//cell development;GO:0006915//apoptotic process;GO:0006470//protein dephosphorylation;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0043383//negative T cell selection;GO:0016337//single organismal cell-cell adhesion;GO:0001933//negative regulation of protein phosphorylation;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0045830//positive regulation of isotype switching;GO:0010212//response to ionizing radiation;GO:0002456//T cell mediated immunity;GO:0001911;GO:0030888//regulation of B cell proliferation;GO:0042492//gamma-delta T cell differentiation;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0030335//positive regulation of cell migration;GO:0043368//positive T cell selection;GO:0051283//negative regulation of sequestering of calcium ion;GO:0010564//regulation of cell cycle process;GO:0050853//B cell receptor signaling pathway;GO:0006929//substrate-dependent cell migration;GO:0000165//MAPK cascade;GO:0042102//positive regulation of T cell proliferation gi|392871558|ref|NP_001255215.1|/0/receptor-type tyrosine-protein phosphatase C precursor [Mus musculus] 74549 5368.62 9.38 8.863333333 -0.081738551 Down 0.189260596 Mau2 MAU2 sister chromatid cohesion factor K11266|1|0.0|1176|pps:100990727|MAternally affected uncoordination GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0005515//protein binding;GO:0005515//protein binding GO:0007064//mitotic sister chromatid cohesion;GO:0007064//mitotic sister chromatid cohesion "gi|148696826|gb|EDL28773.1|/0/RIKEN cDNA 9130404D08, partial [Mus musculus]" 67332 604 36.74 38.19 0.055843294 Up 0.189251194 Snrpd3 small nuclear ribonucleoprotein D3 K11088|1|2e-60|233|tup:102487734|small nuclear ribonucleoprotein D3 GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0003723//RNA binding;GO:0005515//protein binding "GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter" gi|970736200|ref|XP_015102623.1|/1.76378e-59/PREDICTED: small nuclear ribonucleoprotein Sm D3 isoform X1 [Vicugna pacos] 14567 2657 35.03666667 36.48666667 0.05850383 Up 0.189251194 Gdi1 guanosine diphosphate (GDP) dissociation inhibitor 1 K17255|1|0.0|828|mmu:14567|Rab GDP dissociation inhibitor GO:0032991//macromolecular complex;GO:0042995//cell projection;GO:0044424 GO:0008047//enzyme activator activity;GO:0005092//GDP-dissociation inhibitor activity;GO:0017016//Ras GTPase binding;GO:0036094//small molecule binding GO:0010038//response to metal ion;GO:0045184//establishment of protein localization;GO:0007409//axonogenesis;GO:0007154//cell communication "gi|148697875|gb|EDL29822.1|/0/guanosine diphosphate (GDP) dissociation inhibitor 1, isoform CRA_a, partial [Mus musculus]" 56524 2219.9 14.98666667 14.26 -0.071705553 Down 0.189213585 Mpp6 "membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)" K06103|1|1e-113|413|pale:102881573|calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding GO:0065003;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0009117//nucleotide metabolic process gi|257900520|ref|NP_064323.2|/0/MAGUK p55 subfamily member 6 isoform b [Mus musculus] 50997 4142 2.746666667 2.493333333 -0.139606067 Down 0.189175975 Mpp2 "membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)" K06103|1|8e-115|418|pale:102881573|calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1] GO:0044464 GO:0019904//protein domain specific binding - gi|7710062|ref|NP_057904.1|/0/MAGUK p55 subfamily member 2 [Mus musculus] 234515 7746.29 2.506666667 2.76 0.138898106 Up 0.189175975 Inpp4b "inositol polyphosphate-4-phosphatase, type II" K01109|1|0.0|1704|mmu:234515|inositol polyphosphate-4-phosphatase [EC:3.1.3.66] - - - - 101592 3636.98 2.756666667 3.023333333 0.133215221 Up 0.18915717 Efl1 elongation factor like GPTase 1 K14536|1|0.0|2216|mmu:101592|ribosome assembly protein 1 [EC:3.6.5.-] - "GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, RNA binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, RNA binding" GO:0006412//translation;GO:0009154//purine ribonucleotide catabolic process;GO:0042255//ribosome assembly;GO:0006412//translation;GO:0009154//purine ribonucleotide catabolic process;GO:0042255//ribosome assembly "gi|148674951|gb|EDL06898.1|/0/elongation factor Tu GTP binding domain containing 1, isoform CRA_b, partial [Mus musculus]" 73379 6487 2.943333333 3.213333333 0.126619709 Up 0.18915717 Dcbld2 "discoidin, CUB and LCCL domain containing 2" K17253|1|4e-33|147|mgp:100549123|lactadherin GO:0044464;GO:0016021//integral component of membrane - GO:0009611//response to wounding;GO:0016049//cell growth;GO:0007165//signal transduction;GO:0022610 "gi|27476057|ref|NP_082799.2|/0/discoidin, CUB and LCCL domain-containing protein 2 precursor [Mus musculus]" 170799 3932 0.206666667 0.316666667 0.615659298 Up 0.189128963 Rtkn2 rhotekin 2 K18621|1|4e-11|73.6|sko:100376420|actin-binding protein anillin GO:0016020//membrane GO:0008289//lipid binding GO:0048534//hematopoietic or lymphoid organ development;GO:0008283//cell proliferation gi|124486793|ref|NP_001074815.1|/0/rhotekin-2 [Mus musculus] 14381 2639 4.9 5.256666667 0.101366505 Up 0.188875099 G6pdx glucose-6-phosphate dehydrogenase X-linked K00036|1|0.0|1031|ngi:103731231|glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044444//cytoplasmic part "GO:0000166//nucleotide binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0048029//monosaccharide binding" GO:0048469//cell maturation;GO:0006098//pentose-phosphate shunt;GO:0002034//regulation of blood vessel size by renin-angiotensin;GO:0042981//regulation of apoptotic process;GO:0008203//cholesterol metabolic process;GO:0001816//cytokine production;GO:0019321;GO:0006790//sulfur compound metabolic process;GO:0030218//erythrocyte differentiation;GO:0097305//response to alcohol;GO:0035264//multicellular organism growth;GO:0010731//protein glutathionylation;GO:0006979//response to oxidative stress;GO:0031667//response to nutrient levels;GO:0019693//ribose phosphate metabolic process gi|674043799|ref|XP_008827828.1|/0/PREDICTED: glucose-6-phosphate 1-dehydrogenase [Nannospalax galili] 16330 3840.62 5.563333333 5.203333333 -0.096513417 Down 0.188875099 Inpp5b inositol polyphosphate-5-phosphatase B K01099|1|0.0|1617|mmu:16330|inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0046030//inositol trisphosphate phosphatase activity;GO:0043169//cation binding;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0046030//inositol trisphosphate phosphatase activity GO:0046488//phosphatidylinositol metabolic process;GO:0048870//cell motility;GO:0048232//male gamete generation;GO:0016485//protein processing;GO:0007154//cell communication;GO:0046488//phosphatidylinositol metabolic process;GO:0048870//cell motility;GO:0048232//male gamete generation;GO:0016485//protein processing;GO:0007154//cell communication "gi|148698404|gb|EDL30351.1|/0/inositol polyphosphate-5-phosphatase B, isoform CRA_a, partial [Mus musculus]" 13007 1770 35.02 33.60666667 -0.05943163 Down 0.188865696 Csrp1 cysteine and glycine-rich protein 1 K09377|1|3e-88|328|shr:100918475|cysteine and glycine-rich protein GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding GO:0007010//cytoskeleton organization gi|537170965|gb|ERE74332.1|/2.34595e-96/cysteine and glycine-rich protein 1 [Cricetulus griseus] 241230 3166 0.543333333 0.413333333 -0.394531844 Down 0.188856294 St8sia6 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6" "K06615|1|0.0|793|mmu:241230|alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8F) [EC:2.4.99.-]" GO:0031228//intrinsic component of Golgi membrane "GO:0016757//transferase activity, transferring glycosyl groups" GO:0001573//ganglioside metabolic process;GO:0006487//protein N-linked glycosylation gi|74186461|dbj|BAE42986.1|/0/unnamed protein product [Mus musculus] 104721 2488 32.04666667 30.64666667 -0.064444137 Down 0.18879988 Ddx1 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 K13177|1|0.0|1422|mmu:104721|ATP-dependent RNA helicase DDX1 [EC:3.6.4.13] GO:0035770//ribonucleoprotein granule;GO:0016604//nuclear body;GO:0043234//protein complex "GO:0032550;GO:0000989//transcription factor activity, transcription factor binding;GO:0004386//helicase activity;GO:0004518//nuclease activity;GO:0042623//ATPase activity, coupled;GO:0003729//mRNA binding" "GO:0006351//transcription, DNA-templated;GO:0051707//response to other organism;GO:0006396//RNA processing;GO:0043331//response to dsRNA;GO:0032502//developmental process;GO:0032392//DNA geometric change;GO:0006281//DNA repair" gi|19527256|ref|NP_598801.1|/0/ATP-dependent RNA helicase DDX1 [Mus musculus] 98999 5461.26 15.39333333 14.67333333 -0.069109028 Down 0.188790477 Znfx1 "zinc finger, NFX1-type containing 1" K14326|1|2e-29|135|aga:AgaP_AGAP001133|regulator of nonsense transcripts 1 [EC:3.6.4.-] - GO:0043169//cation binding - gi|599045175|ref|NP_001278091.1|/0/NFX1-type zinc finger-containing protein 1 isoform b precursor [Mus musculus] 241732 3087 0.54 0.68 0.332575339 Up 0.18876227 Tspyl3 TSPY-like 3 K11286|1|8e-176|620|mmu:241732|TSPY-like 3 - - GO:0034728//nucleosome organization "gi|148674071|gb|EDL06018.1|/2.22638e-175/mCG49000, partial [Mus musculus]" 210035 6001 0.68 0.54 -0.332575339 Down 0.18876227 Tmem194 nuclear envelope integral membrane protein 1 - - - - - 14531 2034 0.54 0.676666667 0.325485914 Up 0.18876227 Gcm1 glial cells missing homolog 1 (Drosophila) - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding "GO:0021781//glial cell fate commitment;GO:0048598//embryonic morphogenesis;GO:0001892//embryonic placenta development;GO:0006351//transcription, DNA-templated" gi|45433557|ref|NP_032129.2|/0/chorion-specific transcription factor GCMa [Mus musculus] 66302 1875 9.383333333 9.896666667 0.076842171 Up 0.188640039 Rmdn1 regulator of microtubule dynamics 1 - GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle - - gi|31560255|ref|NP_079752.3|/1.11832e-152/regulator of microtubule dynamics protein 1 [Mus musculus] 217473 2458 8.773333333 9.28 0.080999722 Up 0.188640039 Ankmy2 ankyrin repeat and MYND domain containing 2 K15504|1|2e-11|74.3|dre:553206|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - "gi|148704904|gb|EDL36851.1|/0/ankyrin repeat and MYND domain containing 2, isoform CRA_a, partial [Mus musculus]" 56295 1873 36.68666667 35.29333333 -0.055860134 Down 0.188611832 Higd1a "HIG1 domain family, member 1A" - GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane - GO:0001666//response to hypoxia;GO:0009267//cellular response to starvation;GO:0006915//apoptotic process;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization "gi|9789977|ref|NP_062788.1|/4.84232e-47/HIG1 domain family member 1A, mitochondrial [Mus musculus]" 236904 2828.3 0.206666667 0.313333333 0.600392541 Up 0.18856482 Klhl15 kelch-like 15 K10452|1|4e-120|435|mmu:236904|kelch-like protein 15 - - GO:0032446//protein modification by small protein conjugation gi|829865264|ref|XP_012640049.1|/5.81834e-133/PREDICTED: kelch-like protein 15 isoform X1 [Microcebus murinus] 213119 5041 0.23 0.343333333 0.57797607 Up 0.18856482 Itga10 "integrin, alpha 10" K06586|1|0.0|2157|mmu:213119|integrin alpha 10 GO:0005887//integral component of plasma membrane GO:0043169//cation binding;GO:0005515//protein binding GO:0007166//cell surface receptor signaling pathway;GO:0031589//cell-substrate adhesion gi|698607863|ref|NP_001289400.1|/0/integrin alpha-10 precursor [Mus musculus] 66761 1045 0.333333333 0.22 -0.59946207 Down 0.18856482 4933417A18Rik RIKEN cDNA 4933417A18 gene "K13239|1|9e-14|80.1|bom:102278102|peroxisomal 3,2-trans-enoyl-CoA isomerase [EC:5.3.3.8]" - GO:0036094//small molecule binding - gi|118403292|ref|NP_080026.2|/1.98613e-130/uncharacterized protein C6orf201 homolog [Mus musculus] 242037 1759 0.326666667 0.216666667 -0.592342031 Down 0.18856482 Ankub1 ankrin repeat and ubiquitin domain containing 1 - - - - gi|85701850|ref|NP_001028521.1|/1.55208e-108/protein ANKUB1 [Mus musculus] 74244 3918.99 6.223333333 6.643333333 0.094219783 Up 0.188395577 Atg7 autophagy related 7 K08337|1|0.0|1403|mmu:74244|ubiquitin-like modifier-activating enzyme ATG7 GO:0044424;GO:0044424;GO:0044424 GO:0008641//small protein activating enzyme activity;GO:0042802//identical protein binding;GO:0036094//small molecule binding;GO:0008641//small protein activating enzyme activity;GO:0042802//identical protein binding;GO:0036094//small molecule binding;GO:0008641//small protein activating enzyme activity;GO:0042802//identical protein binding;GO:0036094//small molecule binding GO:0010508//positive regulation of autophagy;GO:0007409//axonogenesis;GO:0006915//apoptotic process;GO:0021543//pallium development;GO:0009057//macromolecule catabolic process;GO:0016567//protein ubiquitination;GO:0045184//establishment of protein localization;GO:0021859//pyramidal neuron differentiation;GO:0021695//cerebellar cortex development;GO:0006950//response to stress;GO:0055001//muscle cell development;GO:0003008;GO:0019752//carboxylic acid metabolic process;GO:0008344//adult locomotory behavior;GO:0010508//positive regulation of autophagy;GO:0007409//axonogenesis;GO:0006915//apoptotic process;GO:0021543//pallium development;GO:0009057//macromolecule catabolic process;GO:0016567//protein ubiquitination;GO:0045184//establishment of protein localization;GO:0021859//pyramidal neuron differentiation;GO:0021695//cerebellar cortex development;GO:0006950//response to stress;GO:0055001//muscle cell development;GO:0003008;GO:0019752//carboxylic acid metabolic process;GO:0008344//adult locomotory behavior;GO:0010508//positive regulation of autophagy;GO:0007409//axonogenesis;GO:0006915//apoptotic process;GO:0021543//pallium development;GO:0009057//macromolecule catabolic process;GO:0016567//protein ubiquitination;GO:0045184//establishment of protein localization;GO:0021859//pyramidal neuron differentiation;GO:0021695//cerebellar cortex development;GO:0006950//response to stress;GO:0055001//muscle cell development;GO:0003008;GO:0019752//carboxylic acid metabolic process;GO:0008344//adult locomotory behavior gi|358679369|ref|NP_001240646.1|/0/ubiquitin-like modifier-activating enzyme ATG7 isoform 1 [Mus musculus] 107767 3605 7.21 6.79 -0.086587685 Down 0.188395577 Scamp1 secretory carrier membrane protein 1 K19995|1|1e-165|587|mmu:107767|secretory carrier-associated membrane protein GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle;GO:0030667//secretory granule membrane;GO:0010008//endosome membrane GO:0005515//protein binding GO:0045184//establishment of protein localization;GO:0048193//Golgi vesicle transport gi|58037395|ref|NP_083429.1|/9.47085e-165/secretory carrier-associated membrane protein 1 [Mus musculus] 223626 1600 6.186666667 6.603333333 0.09403217 Up 0.188395577 Them6 thioesterase superfamily member 6 - - - - gi|38348460|ref|NP_941009.1|/2.96625e-103/protein THEM6 precursor [Mus musculus] 66310 704.74 33.64333333 32.28 -0.059680074 Down 0.188386175 Dpy30 "dpy-30, histone methyltransferase complex regulatory subunit" K14965|1|1e-48|194|rno:286897|protein dpy-30 - - - - 191578 3688 1.143333333 0.973333333 -0.232240207 Down 0.18832976 Helq "helicase, POLQ-like" K19178|1|0.0|1946|mmu:191578|POLQ-like helicase [EC:3.6.4.12] GO:0031981//nuclear lumen "GO:0042623//ATPase activity, coupled;GO:0032550" - gi|124487403|ref|NP_001074576.1|/0/helicase POLQ-like [Mus musculus] 56193 4117 0.996666667 1.17 0.231325546 Up 0.18832976 Plek pleckstrin K19993|1|0.0|714|mmu:56193|pleckstrin GO:0044424;GO:0001726//ruffle GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0043168//anion binding;GO:0008289//lipid binding GO:0030097//hemopoiesis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010543//regulation of platelet activation;GO:0051017//actin filament bundle assembly;GO:0006650//glycerophospholipid metabolic process;GO:0030030//cell projection organization;GO:0008361//regulation of cell size;GO:0031334//positive regulation of protein complex assembly;GO:0002576//platelet degranulation;GO:0010922//positive regulation of phosphatase activity;GO:0030042//actin filament depolymerization;GO:0010677 gi|11464971|ref|NP_062422.1|/0/pleckstrin [Mus musculus] 329217 3917 0.97 1.14 0.232977172 Up 0.18832976 Panct2 pluripotency-associated noncoding transcript 2 - - - - - 102634913 2264 1.196666667 1.023333333 -0.225745188 Down 0.18832976 Gm16070 predicted gene 16070 - - - - - 57330 5453 14.54333333 15.25 0.06845127 Up 0.18832976 Gigyf1 GRB10 interacting GYF protein 1 K18730|1|0.0|1314|mmu:57330|PERQ amino acid-rich with GYF domain-containing protein - - GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|154091042|ref|NP_113596.2|/0/PERQ amino acid-rich with GYF domain-containing protein 1 [Mus musculus] 767814 2061 0.24 0.136666667 -0.812372997 Down 0.188320358 AU019990 expressed sequence AU019990 K10591|1|8e-08|61.6|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] GO:0044464;GO:0016021//integral component of membrane - GO:0014706//striated muscle tissue development;GO:0006886//intracellular protein transport gi|537170891|gb|ERE74288.1|/1.83051e-10/E3 ubiquitin-protein ligase [Cricetulus griseus] 212980 3267 3.66 3.373333333 -0.117668764 Down 0.188216932 Slc45a3 "solute carrier family 45, member 3" "K15379|1|0.0|987|mmu:212980|solute carrier family 45, member 3" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763 gi|22122421|ref|NP_666089.1|/0/solute carrier family 45 member 3 [Mus musculus] 74653 3601 3.413333333 3.7 0.116343961 Up 0.188216932 Pomk protein-O-mannose kinase K17547|1|0.0|649|mmu:74653|glycoprotein-mannosyl O6-kinase [EC:2.7.1.183] GO:0031224//intrinsic component of membrane GO:0032550;GO:0016301//kinase activity GO:0016477//cell migration;GO:0007417//central nervous system development;GO:0007600//sensory perception;GO:0006464//cellular protein modification process;GO:0044708//single-organism behavior gi|21312828|ref|NP_083313.1|/0/protein O-mannose kinase [Mus musculus] 67509 2314 3.253333333 3.543333333 0.123188544 Up 0.188216932 Saysd1 SAYSVFN motif domain containing 1 K11722|1|3e-16|89.7|acs:103283041|bromodomain-containing protein 4 - - - gi|218751888|ref|NP_080485.1|/1.44511e-51/SAYSvFN domain-containing protein 1 [Mus musculus] 70314 2539 3.656666667 3.363333333 -0.120637351 Down 0.188216932 Rabep2 "rabaptin, RAB GTPase binding effector protein 2" K20130|1|0.0|813|mmu:70314|Rab GTPase-binding effector protein 2 GO:0005768//endosome GO:0005102//receptor binding GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport gi|140970573|ref|NP_085043.2|/0/rab GTPase-binding effector protein 2 [Mus musculus] 73167 1522.91 1.446666667 1.256666667 -0.203130519 Down 0.188198127 Arhgap8 Rho GTPase activating protein 8 K18470|1|5e-147|523|lcm:102359854|Rho GTPase-activating protein 1 GO:0044464;GO:0044464;GO:0044464;GO:0044464 - GO:0043410//positive regulation of MAPK cascade;GO:0043410//positive regulation of MAPK cascade;GO:0043410//positive regulation of MAPK cascade;GO:0043410//positive regulation of MAPK cascade "gi|92092529|gb|AAH10306.2|/0/Arhgap8 protein, partial [Mus musculus]" 106585 8991 1.45 1.26 -0.202629167 Down 0.188198127 Ankrd12 ankyrin repeat domain 12 K10683|1|8e-32|143|xma:102231240|BRCA1-associated RING domain protein 1 GO:0044424 - - gi|71834683|ref|NP_001020743.1|/0/ankyrin repeat domain-containing protein 12 [Mus musculus] 67676 500 30.35666667 31.69333333 0.062166019 Up 0.188198127 Rpp21 ribonuclease P 21 subunit K03540|1|4e-84|311|mmu:67676|ribonuclease P protein subunit RPR2 [EC:3.1.26.5] GO:0043231//intracellular membrane-bounded organelle GO:0004549//tRNA-specific ribonuclease activity GO:0006399//tRNA metabolic process gi|13385804|ref|NP_080584.1|/2.81633e-83/ribonuclease P protein subunit p21 [Mus musculus] 74201 7904 0.813333333 0.97 0.254138005 Up 0.18813231 Cep97 centrosomal protein 97 K16717|1|3e-79|297|mmu:74201|centrosomal protein CEP97 - - - - 14087 4541 0.84 1 0.251538767 Up 0.18813231 Fanca "Fanconi anemia, complementation group A" K10888|1|0.0|2613|mmu:14087|fanconi anemia group A protein - - - gi|242397507|ref|NP_058621.2|/0/Fanconi anemia group A protein homolog [Mus musculus] 226999 3493 0.863333333 1.023333333 0.245286558 Up 0.18813231 Slc9a2 "solute carrier family 9 (sodium/hydrogen exchanger), member 2" "K14722|1|0.0|1354|mmu:226999|solute carrier family 9 (sodium/hydrogen exchanger), member 2" GO:0044459;GO:0031224//intrinsic component of membrane GO:0005451//monovalent cation:proton antiporter activity GO:0044763;GO:0055067;GO:0006818//hydrogen transport;GO:0033036;GO:0006814//sodium ion transport "gi|148682634|gb|EDL14581.1|/0/solute carrier family 9 (sodium/hydrogen exchanger), member 2, isoform CRA_a, partial [Mus musculus]" 106618 6068 0.553333333 0.426666667 -0.375039431 Down 0.188094701 Wdr90 WD repeat domain 90 K18598|1|2e-26|125|mze:101472726|echinoderm microtubule-associated protein-like 6 - - - gi|255003812|ref|NP_001157238.1|/0/WD repeat-containing protein 90 [Mus musculus] 78934 2402 0.45 0.326666667 -0.462105753 Down 0.188085298 4930581F22Rik RIKEN cDNA 4930581F22 gene - - - - gi|148693429|gb|EDL25376.1|/6.93162e-81/mCG147898 [Mus musculus] 13869 12037 0.313333333 0.43 0.456638404 Up 0.188085298 Erbb4 erb-b2 receptor tyrosine kinase 4 K05085|1|0.0|2676|mmu:13869|receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1] - - - - 209027 2914 0.313333333 0.43 0.456638404 Up 0.188085298 Pycr1 pyrroline-5-carboxylate reductase 1 K00286|1|6e-162|574|mmu:209027|pyrroline-5-carboxylate reductase [EC:1.5.1.2] GO:0043231//intracellular membrane-bounded organelle "GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0005515//protein binding" GO:0006560//proline metabolic process;GO:0006979//response to oxidative stress "gi|755537928|ref|XP_011247156.1|/5.14697e-174/PREDICTED: pyrroline-5-carboxylate reductase 1, mitochondrial isoform X2 [Mus musculus]" 74610 2962 31.22333333 32.55 0.060032979 Up 0.188075896 Abcb8 "ATP-binding cassette, sub-family B (MDR/TAP), member 8" "K05655|1|0.0|1299|mmu:74610|ATP-binding cassette, subfamily B (MDR/TAP), member 8" - - - "gi|27753995|ref|NP_083296.2|/0/ATP-binding cassette sub-family B member 8, mitochondrial precursor [Mus musculus]" 56463 3482 31.80666667 33.13666667 0.059099299 Up 0.188075896 Snd1 staphylococcal nuclease and tudor domain containing 1 K15979|1|0.0|1738|mmu:56463|staphylococcal nuclease domain-containing protein 1 - - - - 64704 1739 13.27 13.97 0.07416365 Up 0.188010079 Htra2 HtrA serine peptidase 2 K08669|1|0.0|766|mmu:64704|HtrA serine peptidase 2 [EC:3.4.21.108] GO:0005740//mitochondrial envelope;GO:0005887//integral component of plasma membrane GO:0004175//endopeptidase activity;GO:0005488//binding GO:0070848//response to growth factor;GO:0006665//sphingolipid metabolic process;GO:0097193//intrinsic apoptotic signaling pathway;GO:0006996//organelle organization;GO:0007420//brain development;GO:0006722;GO:0006950//response to stress;GO:0035264//multicellular organism growth;GO:0019538//protein metabolic process;GO:0030182//neuron differentiation;GO:0008344//adult locomotory behavior gi|74226896|dbj|BAE27092.1|/0/unnamed protein product [Mus musculus] 15356 1416 31.63666667 32.94333333 0.058388939 Up 0.187906653 Hmgcl 3-hydroxy-3-methylglutaryl-Coenzyme A lyase K01640|1|0.0|638|mmu:15356|hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4] GO:0019866//organelle inner membrane;GO:0042579//microbody;GO:0044429 GO:0043168//anion binding;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0016833//oxo-acid-lyase activity GO:0033993//response to lipid;GO:0044249//cellular biosynthetic process;GO:0006996//organelle organization;GO:0051259//protein oligomerization;GO:0031667//response to nutrient levels;GO:0044767//single-organism developmental process;GO:0006732;GO:0007275//multicellular organism development;GO:0006950//response to stress "gi|171543858|ref|NP_032280.2|/1.13661e-180/hydroxymethylglutaryl-CoA lyase, mitochondrial precursor [Mus musculus]" 20962 1132 4.503333333 4.186666667 -0.10519121 Down 0.187897251 Sycp3 synaptonemal complex protein 3 K19528|1|7e-132|472|mmu:20962|synaptonemal complex protein 3 GO:0000795//synaptonemal complex;GO:0043073//germ cell nucleus GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding GO:0044237//cellular metabolic process;GO:0006915//apoptotic process;GO:0016321//female meiosis chromosome segregation;GO:0048232//male gamete generation;GO:0007129//synapsis;GO:0000087//mitotic M phase;GO:0043486//histone exchange gi|226442799|ref|NP_035647.2|/5.99529e-131/synaptonemal complex protein 3 [Mus musculus] 666680 2000 4.2 4.52 0.105933445 Up 0.187897251 Gm8234 spermine synthase pseudogene K00802|1|4e-172|465|rno:363469|spermine synthase [EC:2.5.1.22] GO:0044444//cytoplasmic part "GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups" GO:0006596//polyamine biosynthetic process;GO:0000096//sulfur amino acid metabolic process gi|537136546|gb|ERE66592.1|/2.8199e-172/spermine synthase-like protein [Cricetulus griseus] 74277 2550 4.036666667 4.356666667 0.110060276 Up 0.187897251 Chic2 cysteine-rich hydrophobic domain 2 - "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0016020//membrane" GO:0005488//binding GO:0006892//post-Golgi vesicle-mediated transport gi|327273700|ref|XP_003221618.1|/8.85532e-73/PREDICTED: cysteine-rich hydrophobic domain 2 protein [Anolis carolinensis] 22630 2110 32.46666667 33.75333333 0.056070712 Up 0.187709203 Ywhaq "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide" K16197|1|2e-125|452|ocu:100008930|14-3-3 protein beta/theta/zeta GO:0032991//macromolecular complex;GO:0044424 GO:0005515//protein binding "GO:0035556//intracellular signal transduction;GO:0044710;GO:0006351//transcription, DNA-templated;GO:0006886//intracellular protein transport" "gi|148702066|gb|EDL34013.1|/4.20477e-127/mCG7879, isoform CRA_a, partial [Mus musculus]" 56086 2819.16 32.68666667 33.97333333 0.055700516 Up 0.187709203 Set SET nuclear oncogene K11290|1|2e-125|452|mmu:56086|template-activating factor I GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0019888//protein phosphatase regulator activity;GO:0019212//phosphatase inhibitor activity "GO:0006351//transcription, DNA-templated;GO:0034728//nucleosome organization;GO:0043066//negative regulation of apoptotic process;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0034728//nucleosome organization;GO:0006259//DNA metabolic process;GO:0051169//nuclear transport;GO:0016573//histone acetylation" gi|532004070|ref|XP_005346211.1|/7.77663e-127/PREDICTED: protein SET isoform X2 [Microtus ochrogaster] 17089 1568 13.83666667 13.14333333 -0.074165221 Down 0.18757757 Lyar Ly1 antibody reactive clone K15263|1|8e-175|615|mmu:17089|cell growth-regulating nucleolar protein GO:0031981//nuclear lumen GO:0043169//cation binding - gi|188219567|ref|NP_079557.2|/6.9513e-174/cell growth-regulating nucleolar protein [Mus musculus] 227693 4241 14.83666667 14.14666667 -0.068704845 Down 0.18757757 Zer1 "zyg-11 related, cell cycle regulator" K10350|1|0.0|1560|mmu:227693|Zyg-11 protein homolog GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex - GO:0031396//regulation of protein ubiquitination;GO:0031396//regulation of protein ubiquitination gi|594191015|ref|NP_001277432.1|/0/protein zer-1 homolog isoform b [Mus musculus] 57750 3074.55 5.096666667 5.446666667 0.095819577 Up 0.187511753 Wdr12 WD repeat domain 12 K14863|1|0.0|814|mmu:57750|ribosome biogenesis protein YTM1 GO:0031981//nuclear lumen;GO:0030686//90S preribosome;GO:0031981//nuclear lumen;GO:0030686//90S preribosome;GO:0031981//nuclear lumen;GO:0030686//90S preribosome GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0000470//maturation of LSU-rRNA;GO:0007166//cell surface receptor signaling pathway;GO:0000460//maturation of 5.8S rRNA;GO:0000470//maturation of LSU-rRNA;GO:0007166//cell surface receptor signaling pathway;GO:0000460//maturation of 5.8S rRNA;GO:0000470//maturation of LSU-rRNA;GO:0007166//cell surface receptor signaling pathway;GO:0000460//maturation of 5.8S rRNA gi|10946614|ref|NP_067287.1|/0/ribosome biogenesis protein WDR12 [Mus musculus] 71974 2495 5.31 4.956666667 -0.099341619 Down 0.187511753 Prmt3 protein arginine N-methyltransferase 3 K11436|1|0.0|942|mmu:71974|type I protein arginine methyltransferase [EC:2.1.1.319] GO:0044444//cytoplasmic part;GO:0030529//intracellular ribonucleoprotein complex GO:0046914//transition metal ion binding;GO:0016274//protein-arginine N-methyltransferase activity GO:0035247//peptidyl-arginine omega-N-methylation "gi|148691031|gb|EDL22978.1|/0/protein arginine N-methyltransferase 3, partial [Mus musculus]" 227580 3163 0.433333333 0.316666667 -0.452512205 Down 0.187417729 C1ql3 C1q-like 3 K07296|1|7e-18|95.9|bom:102271886|adiponectin GO:0005576//extracellular region - GO:0050803//regulation of synapse structure or activity gi|729719937|ref|XP_010574630.1|/6.42652e-101/PREDICTED: LOW QUALITY PROTEIN: complement C1q-like protein 3 [Haliaeetus leucocephalus] 12142 5221 0.433333333 0.316666667 -0.452512205 Down 0.187417729 Prdm1 "PR domain containing 1, with ZNF domain" K09228|1|1e-41|175|mze:101487721|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0019899//enzyme binding GO:0006366//transcription from RNA polymerase II promoter;GO:0002832;GO:0003006//developmental process involved in reproduction;GO:0030183//B cell differentiation;GO:0001890//placenta development;GO:0030888//regulation of B cell proliferation;GO:0001701//in utero embryonic development;GO:0001754//eye photoreceptor cell differentiation "gi|125859109|gb|AAI29802.1|/0/Prdm1 protein, partial [Mus musculus]" 100048895 3428 0.46 0.593333333 0.367208974 Up 0.18738012 9330020H09Rik RIKEN cDNA 9330020H09 gene - - - - gi|74150108|dbj|BAE24365.1|/7.77927e-68/unnamed protein product [Mus musculus] 106143 4382 7.136666667 6.723333333 -0.086073712 Down 0.187351912 Cggbp1 CGG triplet repeat binding protein 1 - GO:0031981//nuclear lumen GO:0043566//structure-specific DNA binding "GO:0006351//transcription, DNA-templated" gi|823431689|ref|XP_012422537.1|/4.57488e-102/PREDICTED: LOW QUALITY PROTEIN: CGG triplet repeat-binding protein 1 [Odobenus rosmarus divergens] 269346 3904 6.21 6.62 0.092237949 Up 0.187351912 Slc28a2 "solute carrier family 28 (sodium-coupled nucleoside transporter), member 2" K11536|1|0.0|1272|mmu:269346|pyrimidine nucleoside transport protein GO:0031224//intrinsic component of membrane GO:0036094//small molecule binding;GO:0005337//nucleoside transmembrane transporter activity GO:0072530//purine-containing compound transmembrane transport;GO:0001894//tissue homeostasis;GO:0034613//cellular protein localization gi|27370488|ref|NP_766568.1|/0/sodium/nucleoside cotransporter 2 [Mus musculus] 12748 2320 7.196666667 6.783333333 -0.085334449 Down 0.187351912 Clk2 CDC-like kinase 2 K08823|1|0.0|906|chx:102188369|CDC-like kinase [EC:2.7.12.1] GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity GO:0009314//response to radiation;GO:0033993//response to lipid;GO:0006468//protein phosphorylation;GO:0008380//RNA splicing;GO:0006094//gluconeogenesis "gi|148683287|gb|EDL15234.1|/0/CDC-like kinase 2, isoform CRA_b, partial [Mus musculus]" 232798 5094 31.41 30.14666667 -0.059225452 Down 0.187351912 Leng8 leukocyte receptor cluster (LRC) member 8 - - - - gi|199561284|ref|NP_001032879.2|/0/leukocyte receptor cluster member 8 [Rattus norvegicus] 100526526 87 6.663333333 6.253333333 -0.091618644 Down 0.187351912 Mir3098 microRNA 3098 - - - - - 74154 4404.73 2.656666667 2.913333333 0.133053556 Up 0.187304901 Unkl unkempt family like zinc finger - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003824//catalytic activity - gi|308081466|ref|NP_001183953.1|/0/putative E3 ubiquitin-protein ligase UNKL isoform 1 [Mus musculus] 11789 12453 2.946666667 2.69 -0.131477696 Down 0.187304901 Apc adenomatosis polyposis coli K02085|1|0.0|4608|mmu:11789|adenomatosis polyposis coli protein - - - - 52009 2606 2.796666667 3.053333333 0.126676788 Up 0.187304901 Hn1l hematological and neurological expressed 1-like - GO:0044424;GO:0016020//membrane - - gi|39573709|ref|NP_945175.1|/1.06116e-106/hematological and neurological expressed 1-like protein [Mus musculus] 216766 6199.05 3.016666667 2.756666667 -0.130030463 Down 0.187304901 Gemin5 gem (nuclear organelle) associated protein 5 K13133|1|0.0|2803|mmu:216766|gem associated protein 5 - - - gi|47847430|dbj|BAD21387.1|/0/mFLJ00137 protein [Mus musculus] 72481 1262 1.86 2.076666667 0.158967041 Up 0.187295498 2610203C22Rik RIKEN cDNA 2610203C22 gene - - - - - 214162 16439 2.076666667 1.856666667 -0.161554836 Down 0.187295498 Kmt2a lysine (K)-specific methyltransferase 2A K09186|1|0.0|4637|mmu:214162|histone-lysine N-methyltransferase MLL1 [EC:2.1.1.43] - - - gi|124486682|ref|NP_001074518.1|/0/histone-lysine N-methyltransferase 2A [Mus musculus] 22694 3033 2.063333333 1.843333333 -0.162659929 Down 0.187295498 Zfp35 zinc finger protein 35 K09230|1|0.0|1066|ecb:100052677|SCAN domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0045064//T-helper 2 cell differentiation;GO:0048232//male gamete generation;GO:0002828//regulation of type 2 immune response" gi|83423526|ref|NP_035885.2|/0/zinc finger protein 271 [Mus musculus] 74530 1867 1.93 2.15 0.155735812 Up 0.187295498 9030612E09Rik RIKEN cDNA 9030612E09 gene - - - - gi|148673067|gb|EDL05014.1|/1.00544e-44/RIKEN cDNA 9030612E09 [Mus musculus] 14421 2395.35 1.703333333 1.916666667 0.170238665 Up 0.187286096 B4galnt1 "beta-1,4-N-acetyl-galactosaminyl transferase 1" K00725|1|1e-171|605|mmu:14421|(N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase [EC:2.4.1.92] GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane GO:0008376//acetylgalactosaminyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity GO:0006464//cellular protein modification process;GO:0001573//ganglioside metabolic process;GO:0048232//male gamete generation;GO:0010876//lipid localization;GO:0030258//lipid modification;GO:0006464//cellular protein modification process;GO:0001573//ganglioside metabolic process;GO:0048232//male gamete generation;GO:0010876//lipid localization;GO:0030258//lipid modification;GO:0006464//cellular protein modification process;GO:0001573//ganglioside metabolic process;GO:0048232//male gamete generation;GO:0010876//lipid localization;GO:0030258//lipid modification;GO:0006464//cellular protein modification process;GO:0001573//ganglioside metabolic process;GO:0048232//male gamete generation;GO:0010876//lipid localization;GO:0030258//lipid modification;GO:0006464//cellular protein modification process;GO:0001573//ganglioside metabolic process;GO:0048232//male gamete generation;GO:0010876//lipid localization;GO:0030258//lipid modification "gi|148692528|gb|EDL24475.1|/4.4819e-145/beta-1,4-N-acetyl-galactosaminyl transferase 1, isoform CRA_c, partial [Mus musculus]" 56515 3002.06 1.81 1.603333333 -0.174915304 Down 0.187286096 Rnf138 ring finger protein 138 K10668|1|3e-145|518|mmu:56515|E3 ubiquitin-protein ligase RNF138 [EC:2.3.2.27] GO:0044464;GO:0044464;GO:0044464;GO:0044464 GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0019900//kinase binding;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0019900//kinase binding;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0019900//kinase binding;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0019900//kinase binding GO:0007166//cell surface receptor signaling pathway;GO:0032446//protein modification by small protein conjugation;GO:0007166//cell surface receptor signaling pathway;GO:0032446//protein modification by small protein conjugation;GO:0007166//cell surface receptor signaling pathway;GO:0032446//protein modification by small protein conjugation;GO:0007166//cell surface receptor signaling pathway;GO:0032446//protein modification by small protein conjugation gi|46488941|ref|NP_997506.1|/2.48838e-144/E3 ubiquitin-protein ligase RNF138 isoform 1 [Mus musculus] 12380 3893.3 29.9 28.65333333 -0.061442502 Down 0.187201474 Cast calpastatin K04281|1|0.0|1045|mmu:12380|calpastatin GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005488//binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005488//binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005488//binding;GO:0004869//cysteine-type endopeptidase inhibitor activity GO:0001775//cell activation;GO:0051346//negative regulation of hydrolase activity;GO:0001775//cell activation;GO:0051346//negative regulation of hydrolase activity;GO:0001775//cell activation;GO:0051346//negative regulation of hydrolase activity;GO:0010466//negative regulation of peptidase activity;GO:0001775//cell activation;GO:0010466//negative regulation of peptidase activity;GO:0001775//cell activation;GO:0010466//negative regulation of peptidase activity;GO:0001775//cell activation;GO:0001775//cell activation;GO:0051346//negative regulation of hydrolase activity gi|668259426|ref|NP_001288110.1|/4.03713e-174/calpastatin isoform 8 [Mus musculus] 320502 2242 28.88333333 27.63666667 -0.06365363 Down 0.187201474 Lmod3 leiomodin 3 (fetal) K10370|1|6e-39|165|ola:101175631|tropomodulin - - - - 433956 3445 8.943333333 9.433333333 0.076954998 Up 0.187173267 Dnaaf5 "dynein, axonemal assembly factor 5" "K19759|1|0.0|1354|mmu:433956|dynein assembly factor 5, axonemal" - - - - 237422 4981.37 8.806666667 9.3 0.078634655 Up 0.187173267 Ric8b RIC8 guanine nucleotide exchange factor B - GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0005515//protein binding;GO:0005515//protein binding;GO:0030695//GTPase regulator activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway gi|34147209|ref|NP_898995.1|/0/synembryn-B isoform 2 [Mus musculus] 76954 4328.59 8.416666667 8.906666667 0.08163662 Up 0.187173267 St5 suppression of tumorigenicity 5 K20161|1|0.0|1787|mmu:76954|DENN domain-containing protein 2 - GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0043410//positive regulation of MAPK cascade;GO:0043410//positive regulation of MAPK cascade;GO:0043410//positive regulation of MAPK cascade gi|47679093|ref|NP_001001326.1|/0/suppression of tumorigenicity 5 protein isoform 1 [Mus musculus] 109075 1789 13.51 14.18666667 0.070507975 Up 0.187126255 Exosc4 exosome component 4 K11600|1|6e-121|437|mmu:109075|exosome complex component RRP41 GO:0031981//nuclear lumen;GO:0000785//chromatin GO:0003723//RNA binding;GO:0004518//nuclease activity GO:0016049//cell growth;GO:0006364//rRNA processing;GO:0006304//DNA modification;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0002252 "gi|148697598|gb|EDL29545.1|/2.20488e-134/exosome component 4, isoform CRA_b, partial [Mus musculus]" 23807 3924 14.29333333 14.97 0.066731816 Up 0.187126255 Arih2 ariadne RBR E3 ubiquitin protein ligase 2 K11969|1|0.0|961|mmu:23807|ariadne-2 [EC:2.3.2.27] - - - - 15529 3313 13.12666667 13.81 0.073212709 Up 0.187126255 Sdc2 syndecan 2 K16336|1|2e-83|313|mmu:15529|syndecan 2 GO:0031224//intrinsic component of membrane;GO:0044297//cell body GO:0019904//protein domain specific binding GO:0016358//dendrite development;GO:0009611//response to wounding;GO:0014074//response to purine-containing compound;GO:0010769//regulation of cell morphogenesis involved in differentiation gi|6677891|ref|NP_032330.1|/1.84089e-82/syndecan-2 precursor [Mus musculus] 17975 8257 15.33666667 14.66 -0.065099852 Down 0.187126255 Ncl nucleolin K11294|1|0.0|784|mmu:17975|nucleolin GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding GO:0048646//anatomical structure formation involved in morphogenesis gi|74177681|dbj|BAE38940.1|/0/unnamed protein product [Mus musculus] 100216538 76 0.913333333 0.76 -0.265142069 Down 0.187060439 Snord1a "small nucleolar RNA, C/D box 1A" - - - - - 667931 699 0.736666667 0.89 0.272793372 Up 0.187060439 Gm8883 predicted gene 8883 - - - - - 433791 3691 0.713333333 0.86 0.269760269 Up 0.187060439 Gm13251 zinc finger protein 992 K09228|1|0.0|1230|mmu:666532|KRAB domain-containing zinc finger protein - - - gi|148230208|ref|NP_001078991.1|/0/uncharacterized protein LOC433791 [Mus musculus] 232371 3010 0.72 0.87 0.273018494 Up 0.187060439 C1rl "complement component 1, r subcomponent-like" "K01330|1|8e-122|441|bom:102270366|complement component 1, r subcomponent [EC:3.4.21.41]" GO:0044421 GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0006952//defense response;GO:0002455//humoral immune response mediated by circulating immunoglobulin gi|269973899|ref|NP_851989.3|/0/complement C1r subcomponent-like protein precursor [Mus musculus] 233107 2489 1.33 1.146666667 -0.213980182 Down 0.18694761 Kctd15 potassium channel tetramerisation domain containing 15 "K09672|1|2e-20|103|tru:101061394|carbohydrate 4-sulfotransferase 8 [EC:2.8.2.-];K03849|2|7e-20|102|cmk:103177229|alpha-1,3-glucosyltransferase [EC:2.4.1.265];K15074|3|6e-09|65.9|cbr:CBG18386|BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein;K11835|4|1e-08|65.1|sko:100377510|ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.4.19.12];K20131|5|1e-08|65.1|pale:102883240|Rab5 GDP/GTP exchange factor" - GO:0015075//ion transmembrane transporter activity GO:0051259//protein oligomerization gi|157820509|ref|NP_001102611.1|/8.11403e-149/BTB/POZ domain-containing protein KCTD15 [Rattus norvegicus] 226652 4509 1.113333333 1.29 0.212485464 Up 0.18694761 Arhgap30 Rho GTPase activating protein 30 K17933|1|6e-82|309|ptg:102962608|Rho GTPase-activating protein 33 - - - gi|229608953|ref|NP_001005508.2|/0/rho GTPase-activating protein 30 [Mus musculus] 26360 3444 30.38 31.61333333 0.057411292 Up 0.186938208 Angptl2 angiopoietin-like 2 K05466|1|3e-53|213|bfo:BRAFLDRAFT_231341|angiopoietin 2;K10104|2|3e-53|213|bfo:BRAFLDRAFT_203922|ficolin;K05465|3|3e-53|213|xma:102221719|angiopoietin 1 - - - gi|31560520|ref|NP_036053.2|/0/angiopoietin-related protein 2 precursor [Mus musculus] 213827 3470 28.34333333 27.12 -0.063652259 Down 0.186825379 Arcn1 archain 1 K20471|1|0.0|947|cge:100758971|coatomer subunit delta GO:0030119//AP-type membrane coat adaptor complex;GO:0030120//vesicle coat;GO:0005798//Golgi-associated vesicle GO:0005488//binding GO:0007626//locomotory behavior;GO:0048193//Golgi vesicle transport;GO:0021680//cerebellar Purkinje cell layer development;GO:0015031//protein transport gi|148747410|ref|NP_666097.3|/0/coatomer subunit delta [Mus musculus] 229900 5604 2.446666667 2.69 0.13678861 Up 0.186768965 Gbp7 guanylate binding protein 7 K06128|1|6e-34|108|nle:100581783|lysophospholipase I [EC:3.1.1.5] GO:0031982//vesicle;GO:0020003//symbiont-containing vacuole;GO:0031982//vesicle;GO:0020003//symbiont-containing vacuole - GO:0001562//response to protozoan;GO:0042742//defense response to bacterium;GO:0034341//response to interferon-gamma;GO:0051702//interaction with symbiont;GO:0001562//response to protozoan;GO:0042742//defense response to bacterium;GO:0034341//response to interferon-gamma;GO:0051702//interaction with symbiont gi|47847508|dbj|BAD21426.1|/0/mFLJ00316 protein [Mus musculus] 67228 2952 2.336666667 2.576666667 0.14105397 Up 0.186768965 Dph7 diphthamine biosynethesis 7 K17868|1|0.0|998|mmu:67228|diphthine methyl ester acylhydrolase [EC:3.1.1.97] - - - - 70699 6244 2.673333333 2.43 -0.137683422 Down 0.186768965 Nup205 nucleoporin 205 K14310|1|0.0|3811|mmu:70699|nuclear pore complex protein Nup205 GO:0005635//nuclear envelope;GO:0031981//nuclear lumen GO:0005198//structural molecule activity GO:0006999//nuclear pore organization gi|226437676|ref|NP_081789.1|/0/nuclear pore complex protein Nup205 [Mus musculus] 229731 3383 2.616666667 2.38 -0.13676858 Down 0.186768965 Slc25a24 "solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24" "K14684|1|0.0|955|mmu:229731|solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0051234//establishment of localization;GO:0044763 gi|27369998|ref|NP_766273.1|/0/calcium-binding mitochondrial carrier protein SCaMC-1 [Mus musculus] 68852 2583 2.45 2.693333333 0.136611043 Up 0.186768965 Lrrn4cl LRRN4 C-terminal like - GO:0031224//intrinsic component of membrane - - gi|67846117|ref|NP_001013037.1|/1.41035e-127/LRRN4 C-terminal-like protein precursor [Mus musculus] 280411 2509 13.43 14.1 0.070235858 Up 0.186759562 Lix1l Lix1-like K16673|1|5e-149|531|mmu:280411|LIX1-like protein - - - gi|26341852|dbj|BAC34588.1|/4.48786e-155/unnamed protein product [Mus musculus] 108682 3596 13.51333333 14.18 0.069473944 Up 0.186759562 Gpt2 glutamic pyruvate transaminase (alanine aminotransferase) 2 K00814|1|0.0|1032|mmu:108682|alanine transaminase [EC:2.6.1.2] - - - - 18983 2617 13.2 13.86666667 0.071083098 Up 0.186759562 Cnot7 "CCR4-NOT transcription complex, subunit 7" K12581|1|3e-158|561|oas:101120985|CCR4-NOT transcription complex subunit 7/8 GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0097159//organic cyclic compound binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0097159//organic cyclic compound binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0097159//organic cyclic compound binding;GO:0000175//3'-5'-exoribonuclease activity GO:0006366//transcription from RNA polymerase II promoter;GO:0061014//positive regulation of mRNA catabolic process;GO:0022618//ribonucleoprotein complex assembly;GO:0035194//posttranscriptional gene silencing by RNA;GO:0007154//cell communication;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006366//transcription from RNA polymerase II promoter;GO:0061014//positive regulation of mRNA catabolic process;GO:0022618//ribonucleoprotein complex assembly;GO:0035194//posttranscriptional gene silencing by RNA;GO:0007154//cell communication;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006366//transcription from RNA polymerase II promoter;GO:0061014//positive regulation of mRNA catabolic process;GO:0022618//ribonucleoprotein complex assembly;GO:0035194//posttranscriptional gene silencing by RNA;GO:0007154//cell communication;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening "gi|148703547|gb|EDL35494.1|/3.26498e-161/CCR4-NOT transcription complex, subunit 7, isoform CRA_a, partial [Mus musculus]" 66138 1531 14.03666667 14.70333333 0.066942885 Up 0.186759562 Wbscr22 Williams Beuren syndrome chromosome region 22 K19306|1|2e-151|538|mmu:66138|18S rRNA (guanine1575-N7)-methyltransferase [EC:2.1.1.309] GO:0043231//intracellular membrane-bounded organelle GO:0016741 GO:0008152//metabolic process gi|125988405|ref|NP_079651.2|/1.77821e-150/probable 18S rRNA (guanine-N(7))-methyltransferase [Mus musculus] 50770 7486.58 14.39666667 15.07 0.065944601 Up 0.186759562 Atp11a "ATPase, class VI, type 11A" K01530|1|0.0|2133|mmu:50770|phospholipid-translocating ATPase [EC:3.6.3.1] GO:0031224//intrinsic component of membrane;GO:0005768//endosome GO:0032550;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0003824//catalytic activity GO:0006811//ion transport;GO:0006869//lipid transport gi|652698139|ref|NP_001280596.1|/0/probable phospholipid-transporting ATPase IH isoform 2 [Mus musculus] 27260 1570 0.25 0.146666667 -0.769387072 Down 0.186721953 Plek2 pleckstrin 2 K19993|1|0.0|678|mmu:27260|pleckstrin GO:0030027//lamellipodium;GO:0043232;GO:0016020//membrane GO:0008289//lipid binding GO:0007010//cytoskeleton organization;GO:0007165//signal transduction gi|7305393|ref|NP_038766.1|/0/pleckstrin-2 [Mus musculus] 320842 617 1.166666667 1 -0.222392421 Down 0.186656136 C230035I16Rik RIKEN cDNA C230035I16 gene - - - - - 227094 3377 0.463333333 0.593333333 0.356792358 Up 0.186637331 Tmem194b nuclear envelope integral membrane protein 2 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|217416364|ref|NP_001136119.1|/0/nuclear envelope integral membrane protein 2 precursor [Mus musculus] 207182 2611 0.61 0.476666667 -0.355828502 Down 0.186637331 Ggt7 gamma-glutamyltransferase 7 K00681|1|0.0|1078|mmu:207182|gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] GO:0046658//anchored component of plasma membrane "GO:0016755//transferase activity, transferring amino-acyl groups" GO:0006749//glutathione metabolic process;GO:0006636//unsaturated fatty acid biosynthetic process gi|224994186|ref|NP_659035.2|/0/gamma-glutamyltransferase 7 [Mus musculus] 12804 2029 4.096666667 4.41 0.106328146 Up 0.186486893 Cntfr ciliary neurotrophic factor receptor K05059|1|0.0|666|mmu:12804|ciliary neurotrophic factor receptor - - - - 328092 2564 3.146666667 3.423333333 0.121577417 Up 0.186449284 Dtd2 D-tyrosyl-tRNA deacylase 2 K13113|1|2e-22|110|smm:Smp_094530|ubiquitin-like protein 5;K07560|2|4e-06|56.6|loa:LOAG_06351|D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-] GO:0044424 GO:0016787//hydrolase activity GO:0046416//D-amino acid metabolic process gi|31324532|ref|NP_083821.1|/1.50938e-89/probable D-tyrosyl-tRNA(Tyr) deacylase 2 [Mus musculus] 72925 3942 0.233333333 0.346666667 0.571156701 Up 0.186449284 1-Mar membrane-associated ring finger (C3HC4) 1 K10656|1|2e-158|563|mmu:72925|E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27] GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0031982//vesicle;GO:0005770//late endosome;GO:0005769//early endosome;GO:0031090//organelle membrane;GO:0005802//trans-Golgi network;GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0005770//late endosome;GO:0005769//early endosome;GO:0012506//vesicle membrane;GO:0005802//trans-Golgi network;GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0005770//late endosome;GO:0005769//early endosome;GO:0012506//vesicle membrane;GO:0005802//trans-Golgi network;GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0005770//late endosome;GO:0005769//early endosome;GO:0012506//vesicle membrane;GO:0005802//trans-Golgi network GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0019787//ubiquitin-like protein transferase activity GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0016567//protein ubiquitination;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0016567//protein ubiquitination;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0016567//protein ubiquitination;GO:0002504//antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0016567//protein ubiquitination gi|657940848|ref|NP_001280713.1|/1.41017e-157/E3 ubiquitin-protein ligase MARCH1 isoform 4 [Mus musculus] 77411 2686 0.35 0.236666667 -0.564498398 Down 0.186449284 Esrp2 epithelial splicing regulatory protein 2 K14947|1|0.0|1200|mmu:77411|epithelial splicing regulatory protein 1/2 GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0036094//small molecule binding GO:0008380//RNA splicing gi|28849887|ref|NP_789808.1|/0/epithelial splicing regulatory protein 2 [Mus musculus] 100043125 812 1.546666667 1.75 0.178192617 Up 0.186421076 Gm11711 CD300 molecule like family member D5 K20395|1|2e-96|354|mmu:100043125|CO300B/D/F antigen GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part - GO:0002573//myeloid leukocyte differentiation gi|568970929|ref|XP_006531942.1|/1.19343e-95/PREDICTED: predicted gene 11710 isoform X1 [Mus musculus] 22654 2139 1.543333333 1.746666667 0.178554618 Up 0.186421076 Zfp13 zinc finger protein 13 K09228|1|0.0|1028|mmu:22654|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0010822//positive regulation of mitochondrion organization;GO:0010726//positive regulation of hydrogen peroxide metabolic process;GO:0006351//transcription, DNA-templated" "gi|148690303|gb|EDL22250.1|/0/zinc finger protein 13, isoform CRA_b, partial [Mus musculus]" 71957 2347 8.606666667 9.086666667 0.078296561 Up 0.186402272 Cpsf3l cleavage and polyadenylation specific factor 3-like K13148|1|0.0|1217|mmu:71957|integrator complex subunit 11 [EC:3.1.27.-] GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity - gi|21312614|ref|NP_082296.1|/0/integrator complex subunit 11 [Mus musculus] 20354 4497.35 8.943333333 8.466666667 -0.079018558 Down 0.186402272 Sema4d "sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D" K06521|1|0.0|1645|mmu:20354|semaphorin 4 GO:0016021//integral component of membrane;GO:0044421;GO:0016021//integral component of membrane;GO:0044421 GO:0005102//receptor binding;GO:0038023//signaling receptor activity;GO:0005102//receptor binding;GO:0038023//signaling receptor activity GO:0071526//semaphorin-plexin signaling pathway;GO:0006915//apoptotic process;GO:0007159//leukocyte cell-cell adhesion;GO:0009967//positive regulation of signal transduction;GO:0001933//negative regulation of protein phosphorylation;GO:0016477//cell migration;GO:0007409//axonogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0001649//osteoblast differentiation;GO:0006935//chemotaxis;GO:0030307//positive regulation of cell growth;GO:0010692;GO:0002376//immune system process;GO:0006366//transcription from RNA polymerase II promoter;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0071526//semaphorin-plexin signaling pathway;GO:0006915//apoptotic process;GO:0007159//leukocyte cell-cell adhesion;GO:0009967//positive regulation of signal transduction;GO:0001933//negative regulation of protein phosphorylation;GO:0016477//cell migration;GO:0007409//axonogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0001649//osteoblast differentiation;GO:0006935//chemotaxis;GO:0030307//positive regulation of cell growth;GO:0010692;GO:0002376//immune system process;GO:0006366//transcription from RNA polymerase II promoter;GO:0010769//regulation of cell morphogenesis involved in differentiation gi|49274623|ref|NP_038688.2|/0/semaphorin-4D precursor [Mus musculus] 22284 11903 8.413333333 7.933333333 -0.084750337 Down 0.186402272 Usp9x "ubiquitin specific peptidase 9, X chromosome" K11840|1|0.0|4960|mmu:22284|ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12] GO:0044424 "GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016790//thiolester hydrolase activity;GO:0046332//SMAD binding" GO:0019941//modification-dependent protein catabolic process;GO:0000087//mitotic M phase;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0070646//protein modification by small protein removal gi|115511018|ref|NP_033507.2|/0/probable ubiquitin carboxyl-terminal hydrolase FAF-X [Mus musculus] 67151 2610 9.206666667 8.73 -0.07669726 Down 0.186402272 Psmd9 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 9" K06693|1|1e-104|383|mmu:67151|26S proteasome non-ATPase regulatory subunit 9 GO:0031981//nuclear lumen;GO:0005838//proteasome regulatory particle;GO:0044444//cytoplasmic part GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding "GO:0006915//apoptotic process;GO:0044764;GO:0006520//cellular amino acid metabolic process;GO:0043248//proteasome assembly;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0044772//mitotic cell cycle phase transition;GO:0051320;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0050796//regulation of insulin secretion" gi|12848446|dbj|BAB27957.1|/5.94363e-116/unnamed protein product [Mus musculus] 21917 3644.89 8.746666667 9.226666667 0.077076223 Up 0.186402272 Tmpo thymopoietin K15710|1|1e-11|75.5|xtr:101733375|E3 ubiquitin-protein ligase SHPRH [EC:3.6.4.- 2.3.2.27];K06756|2|2e-08|65.1|ccw:104698317|neuronal cell adhesion molecule;K10481|3|4e-06|57.0|gja:107119524|BTB/POZ domain-containing protein 9 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0019866//organelle inner membrane;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0019866//organelle inner membrane;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0043232;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0043232;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0019866//organelle inner membrane;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0019866//organelle inner membrane;GO:0012505//endomembrane system GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding "GO:0006998//nuclear envelope organization;GO:0006351//transcription, DNA-templated;GO:0006998//nuclear envelope organization;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006998//nuclear envelope organization;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|121949767|ref|NP_001073599.1|/0/lamina-associated polypeptide 2 isoform delta [Mus musculus] 78928 2574 26.89 28.07666667 0.06230191 Up 0.186392869 Pigt "phosphatidylinositol glycan anchor biosynthesis, class T" "K05292|1|0.0|1090|mmu:78928|phosphatidylinositol glycan, class T" GO:0030176//integral component of endoplasmic reticulum membrane GO:0005488//binding;GO:0016787//hydrolase activity GO:0070997//neuron death;GO:0030154//cell differentiation;GO:0006497//protein lipidation gi|120587021|ref|NP_598540.2|/0/GPI transamidase component PIG-T precursor [Mus musculus] 327762 4122 0.153333333 0.256666667 0.743224585 Up 0.186374064 Dna2 DNA replication helicase/nuclease 2 K10742|1|0.0|2072|mmu:327762|DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12] - - - - 20408 1641 0.143333333 0.24 0.743660247 Up 0.186374064 Sh3gl3 SH3-domain GRB2-like 3 K11247|1|0.0|665|mmu:20408|endophilin-A GO:0005769//early endosome;GO:0005769//early endosome;GO:0005769//early endosome GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0007399//nervous system development;GO:0016192//vesicle-mediated transport;GO:0007154//cell communication;GO:0016192//vesicle-mediated transport;GO:0007399//nervous system development;GO:0016192//vesicle-mediated transport;GO:0007154//cell communication gi|223468646|ref|NP_059096.3|/0/endophilin-A3 isoform 1 [Mus musculus] 545812 1807 0.153333333 0.256666667 0.743224585 Up 0.186374064 Pilrb2 paired immunoglobin-like type 2 receptor beta 2 K15411|1|1e-77|293|mmu:231805|paired immunoglobulin-like type 2 receptor alpha GO:0031224//intrinsic component of membrane GO:0042287//MHC protein binding GO:0002762//negative regulation of myeloid leukocyte differentiation gi|568938512|ref|XP_006504669.1|/6.48607e-142/PREDICTED: paired immunoglobulin-like type 2 receptor beta-2 isoform X1 [Mus musculus] 77626 4618.55 6.826666667 6.426666667 -0.087110664 Down 0.186327053 Smpd4 sphingomyelin phosphodiesterase 4 K12353|1|0.0|1546|mmu:77626|sphingomyelin phosphodiesterase 4 [EC:3.1.4.12] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0004620//phospholipase activity;GO:0043169//cation binding;GO:0004620//phospholipase activity;GO:0043169//cation binding;GO:0004620//phospholipase activity;GO:0043169//cation binding;GO:0004620//phospholipase activity GO:0006684//sphingomyelin metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0034612//response to tumor necrosis factor;GO:0006684//sphingomyelin metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0034612//response to tumor necrosis factor;GO:0006684//sphingomyelin metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0034612//response to tumor necrosis factor;GO:0006684//sphingomyelin metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0034612//response to tumor necrosis factor "gi|148665056|gb|EDK97472.1|/0/sphingomyelin phosphodiesterase 4, isoform CRA_c, partial [Mus musculus]" 94181 1904 7.023333333 6.62 -0.085324691 Down 0.186327053 Nans N-acetylneuraminic acid synthase (sialic acid synthase) K05304|1|0.0|729|mmu:94181|sialic acid synthase [EC:2.5.1.56 2.5.1.57] GO:0044444//cytoplasmic part "GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0070567" GO:0008610//lipid biosynthetic process;GO:0044723 gi|16716467|ref|NP_444409.1|/0/sialic acid synthase [Mus musculus] 68310 3832 0.77 0.923333333 0.261993125 Up 0.186327053 Zmym1 "zinc finger, MYM domain containing 1" K13126|1|8e-21|105|api:100159206|polyadenylate-binding protein;K14829|2|1e-18|98.6|hmg:100196989|pre-rRNA-processing protein IPI3;K10134|3|3e-11|73.9|api:100159951|etoposide-induced 2.4 mRNA - GO:0005515//protein binding;GO:0046914//transition metal ion binding - gi|49227135|ref|NP_080946.3|/0/zinc finger MYM-type protein 1 [Mus musculus] 207259 4591 0.933333333 0.78 -0.258918297 Down 0.186327053 Zbtb7c zinc finger and BTB domain containing 7C K10494|1|0.0|1037|mmu:207259|zinc finger and BTB domain-containing protein 7 GO:0044464 GO:0046914//transition metal ion binding - gi|755560628|ref|XP_011245167.1|/0/PREDICTED: zinc finger and BTB domain-containing protein 7C isoform X2 [Mus musculus] 20587 1650.43 13.5 12.84 -0.072314205 Down 0.186298845 Smarcb1 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1" K11648|1|0.0|754|pale:102881630|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 - - - gi|55956801|ref|NP_001007469.1|/0/SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform b [Homo sapiens] 14276 1090.03 12.57333333 13.23 0.073445886 Up 0.186298845 Folr2 folate receptor 2 (fetal) K13649|1|1e-148|528|mmu:14276|folate receptor GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0051183//vitamin transporter activity;GO:0051183//vitamin transporter activity;GO:0051183//vitamin transporter activity GO:0006835//dicarboxylic acid transport;GO:0006612//protein targeting to membrane;GO:0006835//dicarboxylic acid transport;GO:0006612//protein targeting to membrane;GO:0006835//dicarboxylic acid transport;GO:0006612//protein targeting to membrane gi|568949680|ref|XP_006507434.1|/3.70865e-171/PREDICTED: folate receptor beta isoform X1 [Mus musculus] 20926 6201 13.23666667 13.9 0.070545023 Up 0.186298845 Supt6 suppressor of Ty 6 K11292|1|0.0|2812|mmu:20926|transcription elongation factor SPT6 GO:0043231//intracellular membrane-bounded organelle GO:0016787//hydrolase activity "GO:0006354//DNA-templated transcription, elongation;GO:0006366//transcription from RNA polymerase II promoter" gi|166091434|ref|NP_033323.2|/0/transcription elongation factor SPT6 [Mus musculus] 14344 3035.65 1.566666667 1.376666667 -0.186518975 Down 0.186289443 Fut2 fucosyltransferase 2 K00718|1|0.0|712|mmu:14344|galactoside 2-L-fucosyltransferase 1/2 [EC:2.4.1.69] GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane "GO:0031127//alpha-(1,2)-fucosyltransferase activity;GO:0031127//alpha-(1,2)-fucosyltransferase activity" GO:0006464//cellular protein modification process;GO:0070085//glycosylation;GO:0006464//cellular protein modification process;GO:0070085//glycosylation gi|31542827|ref|NP_061364.2|/0/galactoside 2-alpha-L-fucosyltransferase 2 [Mus musculus] 619597 4068 0.476666667 0.353333333 -0.431950882 Down 0.186280041 Gm6086 predicted gene 6086 K09675|1|0.0|706|mmu:619597|galactose-3-O-sulfotransferase 2 [EC:2.8.2.-] - GO:0008146//sulfotransferase activity GO:0006790//sulfur compound metabolic process gi|85986609|ref|NP_001034308.1|/0/galactose-3-O-sulfotransferase 2-like [Mus musculus] 101809 4094 0.453333333 0.336666667 -0.429251358 Down 0.186280041 Spred3 "sprouty-related, EVH1 domain containing 3" "K04703|1|2e-148|529|mmu:101809|sprouty-related, EVH1 domain-containing protein" GO:0016020//membrane GO:0005126//cytokine receptor binding GO:0007165//signal transduction "gi|188219587|ref|NP_891557.3|/2.06634e-147/sprouty-related, EVH1 domain-containing protein 3 [Mus musculus]" 240131 1759 0.236666667 0.346666667 0.550692599 Up 0.186063786 Lrrc30 leucine rich repeat containing 30 K19613|1|3e-19|99.4|tca:656574|leucine-rich repeat protein SHOC2 - - - gi|255003784|ref|NP_001028512.2|/1.58029e-161/leucine-rich repeat-containing protein 30 [Mus musculus] 11423 2224 0.706666667 0.57 -0.31006794 Down 0.186016774 Ache acetylcholinesterase K01049|1|0.0|1175|mmu:11423|acetylcholinesterase [EC:3.1.1.7] - - - - 93838 3158 0.596666667 0.74 0.310600089 Up 0.186016774 Dqx1 DEAQ RNA-dependent ATPase K14433|1|0.0|1263|mmu:93838|ATP-dependent RNA helicase DQX1 [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle GO:0017111//nucleoside-triphosphatase activity;GO:0032550 - gi|19424112|ref|NP_291084.1|/0/ATP-dependent RNA helicase DQX1 [Mus musculus] 12952 3035 4.973333333 4.636666667 -0.101125116 Down 0.186007371 Cry1 cryptochrome 1 (photolyase-like) K02295|1|0.0|1217|mmu:12952|cryptochrome GO:0043231//intracellular membrane-bounded organelle GO:0019900//kinase binding;GO:0003913//DNA photolyase activity;GO:0038023//signaling receptor activity;GO:0036094//small molecule binding;GO:0043566//structure-specific DNA binding GO:0006259//DNA metabolic process;GO:0006464//cellular protein modification process;GO:0007623//circadian rhythm;GO:0006366//transcription from RNA polymerase II promoter "gi|514830115|pdb|4K0R|A/0/Chain A, Crystal Structure Of Mouse Cryptochrome 1" 106707 1703 4.97 4.626666667 -0.10327269 Down 0.186007371 Rpusd1 RNA pseudouridylate synthase domain containing 1 - - GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity GO:0016070//RNA metabolic process gi|28076995|ref|NP_082285.1|/5.1956e-170/RNA pseudouridylate synthase domain-containing protein 1 [Mus musculus] 67490 4335 4.893333333 4.556666667 -0.102838725 Down 0.186007371 Ufl1 UFM1 specific ligase 1 - GO:0031981//nuclear lumen GO:0019787//ubiquitin-like protein transferase activity GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0016567//protein ubiquitination gi|227330590|ref|NP_080470.2|/0/E3 UFM1-protein ligase 1 [Mus musculus] 103677 5817 5 5.343333333 0.095811925 Up 0.186007371 Smg6 "Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)" K11124|1|0.0|2481|mmu:103677|protein SMG6 [EC:3.1.-.-] GO:0044427;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0004519//endonuclease activity;GO:0043565//sequence-specific DNA binding GO:0006259//DNA metabolic process "gi|148680843|gb|EDL12790.1|/0/Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans), isoform CRA_a [Mus musculus]" 70567 1400 4.92 5.26 0.096404484 Up 0.186007371 Fra10ac1 FRA10AC1 homolog (human) K13121|1|2e-164|581|mmu:70567|protein FRA10AC1 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding - gi|26346440|dbj|BAC36871.1|/0/unnamed protein product [Mus musculus] 27374 2622.48 25.23666667 26.39333333 0.064652199 Up 0.185979164 Prmt5 protein arginine N-methyltransferase 5 K02516|1|0.0|1299|ngi:103739477|type II protein arginine methyltransferase [EC:2.1.1.320] - - - - 244668 6365 13.71 13.06 -0.070073674 Down 0.185941555 Sipa1l2 signal-induced proliferation-associated 1 like 2 K17702|1|0.0|3031|mmu:244668|signal-induced proliferation-associated 1 like protein 2 - - GO:0007264//small GTPase mediated signal transduction gi|124487493|ref|NP_001074806.1|/0/signal-induced proliferation-associated 1-like protein 2 [Mus musculus] 22227 1644 0.066666667 0.01 -2.736965594 Down 0.185866336 Ucp1 "uncoupling protein 1 (mitochondrial, proton carrier)" "K08769|1|1e-172|608|mmu:22227|solute carrier family 25 (mitochondrial uncoupling protein), member 7" GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0005740//mitochondrial envelope GO:0022857//transmembrane transporter activity GO:0009893//positive regulation of metabolic process;GO:0006818//hydrogen transport;GO:0009725//response to hormone;GO:0006366//transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation gi|6678497|ref|NP_033489.1|/9.06388e-172/mitochondrial brown fat uncoupling protein 1 [Mus musculus] 238333 2028 0.01 0.066666667 2.736965594 Up 0.185866336 Samd15 sterile alpha motif domain containing 15 K04574|1|2e-06|57.4|cmy:102946809|neurofilament heavy polypeptide;K12567|5|6e-06|55.5|oas:101122837|titin [EC:2.7.11.1] - - - gi|590121987|ref|NP_001277217.1|/0/sterile alpha motif domain-containing protein 15 [Mus musculus] 622167 808 0.01 0.066666667 2.736965594 Up 0.185866336 Gm12718 predicted gene 12718 - - - - - 75589 698 0.01 0.066666667 2.736965594 Up 0.185866336 2310043L19Rik RIKEN cDNA 2310043L19 gene - - - - - 72236 2210 0.01 0.066666667 2.736965594 Up 0.185866336 Tsnaxip1 translin-associated factor X (Tsnax) interacting protein 1 K00547|1|3e-58|229|pxy:105390301|homocysteine S-methyltransferase [EC:2.1.1.10];K10352|2|2e-07|60.5|amj:102560042|myosin heavy chain;K20282|3|8e-07|58.5|ola:101160697|GRIP and coiled-coil domain-containing protein 2;K20478|4|1e-06|57.8|dre:557772|golgin subfamily B member 1 GO:0044424 - GO:0048232//male gamete generation;GO:0048869//cellular developmental process "gi|13161243|gb|AAK13524.1|AF343750_1/0/Trax-interacting protein 1, partial [Mus musculus]" 16992 1423 0.01 0.066666667 2.736965594 Up 0.185866336 Lta lymphotoxin A "K05468|1|6e-92|340|mmu:16992|lymphotoxin alpha (TNF superfamily, member 1)" - - - - 78617 833 0.066666667 0.01 -2.736965594 Down 0.185866336 Cstad "CSA-conditional, T cell activation-dependent protein" - GO:0031966//mitochondrial membrane - GO:0007005//mitochondrion organization "gi|33469017|ref|NP_084413.1|/8.89914e-58/CSA-conditional, T cell activation-dependent protein [Mus musculus]" 100041596 1185 0.066666667 0.01 -2.736965594 Down 0.185866336 Gm9994 predicted gene 9994 K09675|1|0.0|724|mmu:100041596|galactose-3-O-sulfotransferase 2 [EC:2.8.2.-] - GO:0008146//sulfotransferase activity GO:0006790//sulfur compound metabolic process gi|327412325|ref|NP_001192178.1|/0/galactose-3-O-sulfotransferase 2 [Mus musculus] 67741 1598 0.066666667 0.01 -2.736965594 Down 0.185866336 4930579F01Rik RIKEN cDNA 4930579F01 gene - - - - gi|254281182|ref|NP_001156857.1|/0/uncharacterized protein C4orf17 homolog isoform 1 [Mus musculus] 72628 835 0.066666667 0.01 -2.736965594 Down 0.185866336 Hoxaas3 Hoxa cluster antisense RNA 3 K09306|1|2e-41|171|rno:100909604|homeobox protein HoxA/B/C6 - - - - 75887 881 0.066666667 0.01 -2.736965594 Down 0.185866336 4930586N03Rik RIKEN cDNA 4930586N03 gene - - - - - 64242 1630 0.066666667 0.01 -2.736965594 Down 0.185866336 Ngb neuroglobin K13825|1|2e-07|60.1|fpg:101916119|hemoglobin subunit epsilon GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043025//neuronal cell body;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043025//neuronal cell body GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0022892//substrate-specific transporter activity;GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0022892//substrate-specific transporter activity GO:0012501//programmed cell death;GO:0015669;GO:0012501//programmed cell death;GO:0015669 "gi|149025256|gb|EDL81623.1|/6.65426e-85/neuroglobin, isoform CRA_a [Rattus norvegicus]" 229277 864 0.066666667 0.01 -2.736965594 Down 0.185866336 Stoml3 stomatin (Epb7.2)-like 3 K17286|1|2e-142|506|mmu:229277|erythrocyte band 7 integral membrane protein GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0007154//cell communication "gi|37194829|gb|AAH58224.1|/1.82896e-141/Stoml3 protein, partial [Mus musculus]" 108812 1575 0.01 0.066666667 2.736965594 Up 0.185866336 Als2cr12 "amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12 (human)" K06674|1|3e-06|55.8|tgu:100232341|structural maintenance of chromosome 2;K16728|2|7e-06|54.7|clv:102092128|centrosomal protein CEP152;K16767|3|7e-06|54.7|mmu:76380|centrosomal protein CEP112;K16469|4|1e-05|54.3|phu:Phum_PHUM376800|rootletin GO:0044441 - - "gi|148667677|gb|EDL00094.1|/0/mCG117851, isoform CRA_c, partial [Mus musculus]" 58867 826 0.01 0.066666667 2.736965594 Up 0.185866336 Syngr4 synaptogyrin 4 K04403|1|7e-21|103|gfr:102037151|TAK1-binding protein 1;K17783|2|4e-20|100|shr:100917660|mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|50403812|sp|Q9Z1L2.2|SNG4_MOUSE/1.43946e-108/RecName: Full=Synaptogyrin-4 353155 837 0.066666667 0.01 -2.736965594 Down 0.185866336 Gjd3 "gap junction protein, delta 3" "K07627|1|6e-110|399|mmu:353155|gap junction protein, chi 1" GO:0005921//gap junction;GO:0044464;GO:0044425 GO:0015075//ion transmembrane transporter activity GO:0007043//cell-cell junction assembly;GO:0006811//ion transport gi|116174744|ref|NP_848711.2|/5.04444e-109/gap junction delta-3 protein [Mus musculus] 622070 832 0.066666667 0.01 -2.736965594 Down 0.185866336 Gm15133 predicted gene 15133 - - - - - 73339 840 0.066666667 0.01 -2.736965594 Down 0.185866336 1700047G03Rik RIKEN cDNA 1700047G03 gene - - - - "gi|148671329|gb|EDL03276.1|/7.02793e-26/mCG1026161, isoform CRA_b [Mus musculus]" 69327 833 0.066666667 0.01 -2.736965594 Down 0.185866336 1700007K13Rik RIKEN cDNA 1700007K13 gene - - - - gi|110625742|ref|NP_081316.1|/1.19997e-62/UPF0691 protein C9orf116 homolog [Mus musculus] 56856 3102 0.01 0.066666667 2.736965594 Up 0.185866336 Insm2 insulinoma-associated 2 K09228|1|3e-11|73.6|oaa:100090694|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|154090939|ref|NP_064683.2|/0/insulinoma-associated protein 2 [Mus musculus] 100502876 720 0.01 0.066666667 2.736965594 Up 0.185866336 Kcnmb3 "potassium large conductance calcium-activated channel, subfamily M, beta member 3" K04939|1|3e-133|476|mmu:100502876|potassium large conductance calcium-activated channel subfamily M beta member 3 - - - - 238896 1560 0.066666667 0.01 -2.736965594 Down 0.185866336 Cdc20b cell division cycle 20B "K03363|1|2e-88|328|cmk:103177878|cell division cycle 20, cofactor of APC complex" - - - gi|527498264|ref|NP_001268416.1|/0/cell division cycle protein 20 homolog B [Mus musculus] 18576 5314 0.46 0.343333333 -0.42202393 Down 0.185819324 Pde3b "phosphodiesterase 3B, cGMP-inhibited" "K13296|1|0.0|1791|mmu:18576|cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex "GO:0019901//protein kinase binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0030551//cyclic nucleotide binding;GO:0043169//cation binding" GO:0001525//angiogenesis;GO:0031016//pancreas development;GO:0032868//response to insulin;GO:0007155//cell adhesion;GO:0033500//carbohydrate homeostasis;GO:0050796//regulation of insulin secretion;GO:0009895;GO:0046058//cAMP metabolic process;GO:0006721//terpenoid metabolic process "gi|112983648|ref|NP_035185.2|/0/cGMP-inhibited 3',5'-cyclic phosphodiesterase B [Mus musculus]" 18823 3368 0.493333333 0.37 -0.415037499 Down 0.185819324 Plp1 proteolipid protein (myelin) 1 K17271|1|4e-162|575|cfr:102504737|myelin proteolipid protein GO:0016021//integral component of membrane;GO:0044464;GO:0016021//integral component of membrane;GO:0044464;GO:0016021//integral component of membrane;GO:0044464 GO:0005488//binding;GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity GO:0008366//axon ensheathment;GO:0007267//cell-cell signaling;GO:0007166//cell surface receptor signaling pathway;GO:0001676//long-chain fatty acid metabolic process;GO:0021700//developmental maturation;GO:0010467//gene expression;GO:0014003//oligodendrocyte development;GO:0008366//axon ensheathment;GO:0007267//cell-cell signaling;GO:0007166//cell surface receptor signaling pathway;GO:0001676//long-chain fatty acid metabolic process;GO:0021700//developmental maturation;GO:0010467//gene expression;GO:0014003//oligodendrocyte development;GO:0008366//axon ensheathment;GO:0007267//cell-cell signaling;GO:0007166//cell surface receptor signaling pathway;GO:0001676//long-chain fatty acid metabolic process;GO:0021700//developmental maturation;GO:0010467//gene expression;GO:0014003//oligodendrocyte development gi|521027133|gb|EPQ08921.1|/1.60151e-161/Myelin proteolipid protein [Myotis brandtii] 67667 2300 0.493333333 0.37 -0.415037499 Down 0.185819324 Alkbh8 "alkB homolog 8, tRNA methyltransferase" K10770|1|0.0|1307|mmu:67667|alkylated DNA repair protein alkB homolog 8 [EC:1.14.11.- 2.1.1.229] - - - - 18795 6998 0.486666667 0.363333333 -0.421640234 Down 0.185819324 Plcb1 "phospholipase C, beta 1" "K05858|1|0.0|2138|mmu:18795|phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]" GO:0016604//nuclear body;GO:0005635//nuclear envelope;GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0016604//nuclear body;GO:0005635//nuclear envelope;GO:0000785//chromatin;GO:0044444//cytoplasmic part GO:0060089;GO:0046872//metal ion binding;GO:0008047//enzyme activator activity;GO:0004629//phospholipase C activity;GO:0042802//identical protein binding;GO:0043168//anion binding;GO:0060089;GO:0046872//metal ion binding;GO:0008047//enzyme activator activity;GO:0004629//phospholipase C activity;GO:0042802//identical protein binding;GO:0043168//anion binding "GO:0022403;GO:0045445//myoblast differentiation;GO:0032415//regulation of sodium:proton antiporter activity;GO:0003006//developmental process involved in reproduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0002692//negative regulation of cellular extravasation;GO:0021543//pallium development;GO:0009790//embryo development;GO:0006396//RNA processing;GO:0006351//transcription, DNA-templated;GO:0007611//learning or memory;GO:2000241//regulation of reproductive process;GO:0019221//cytokine-mediated signaling pathway;GO:0007254//JNK cascade;GO:0045927//positive regulation of growth;GO:0001819//positive regulation of cytokine production;GO:0022610;GO:0006650//glycerophospholipid metabolic process;GO:0007340//acrosome reaction;GO:0007343//egg activation;GO:0007267//cell-cell signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010560//positive regulation of glycoprotein biosynthetic process;GO:0043087//regulation of GTPase activity;GO:0002573//myeloid leukocyte differentiation;GO:1901992//positive regulation of mitotic cell cycle phase transition;GO:0009725//response to hormone;GO:0009743//response to carbohydrate;GO:0022403;GO:0045445//myoblast differentiation;GO:0032415//regulation of sodium:proton antiporter activity;GO:0003006//developmental process involved in reproduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0002692//negative regulation of cellular extravasation;GO:0021543//pallium development;GO:0009790//embryo development;GO:0006396//RNA processing;GO:0006351//transcription, DNA-templated;GO:0007611//learning or memory;GO:2000241//regulation of reproductive process;GO:0019221//cytokine-mediated signaling pathway;GO:0007254//JNK cascade;GO:0045927//positive regulation of growth;GO:0001819//positive regulation of cytokine production;GO:0022610;GO:0006650//glycerophospholipid metabolic process;GO:0007340//acrosome reaction;GO:0007343//egg activation;GO:0007267//cell-cell signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010560//positive regulation of glycoprotein biosynthetic process;GO:0043087//regulation of GTPase activity;GO:0002573//myeloid leukocyte differentiation;GO:1901992//positive regulation of mitotic cell cycle phase transition;GO:0009725//response to hormone;GO:0009743//response to carbohydrate" "gi|224967070|ref|NP_001139302.1|/0/1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform 1 [Mus musculus]" 101214 1839 8.556666667 9.023333333 0.076611592 Up 0.185715898 Tra2a transformer 2 alpha homolog (Drosophila) K12897|1|7e-56|221|oaa:100083072|transformer-2 protein GO:0043231//intracellular membrane-bounded organelle GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding GO:0000377 gi|149033412|gb|EDL88213.1|/6.15054e-55/similar to RIKEN cDNA G430041M01 (predicted) [Rattus norvegicus] 18174 3712.6 8.473333333 8.946666667 0.078420641 Up 0.185715898 Slc11a2 "solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2" K12347|1|0.0|959|mmu:18174|natural resistance-associated macrophage protein GO:0031982//vesicle;GO:0005764//lysosome;GO:0016021//integral component of membrane;GO:0005770//late endosome;GO:0043234//protein complex;GO:0042995//cell projection;GO:0044459;GO:0031982//vesicle;GO:0005764//lysosome;GO:0016021//integral component of membrane;GO:0005770//late endosome;GO:0043234//protein complex;GO:0042995//cell projection;GO:0044459 GO:0046914//transition metal ion binding;GO:0005381//iron ion transmembrane transporter activity;GO:0015294//solute:cation symporter activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0046914//transition metal ion binding;GO:0005381//iron ion transmembrane transporter activity;GO:0015294//solute:cation symporter activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0016358//dendrite development;GO:0015675//nickel cation transport;GO:0015691//cadmium ion transport;GO:0006818//hydrogen transport;GO:0015684//ferrous iron transport;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0055080//cation homeostasis;GO:0010039//response to iron ion;GO:0006915//apoptotic process;GO:0034612//response to tumor necrosis factor;GO:0001666//response to hypoxia;GO:0030218//erythrocyte differentiation;GO:0006829//zinc II ion transport;GO:0006825//copper ion transport;GO:0009593//detection of chemical stimulus;GO:0006979//response to oxidative stress;GO:0006828//manganese ion transport;GO:0044708//single-organism behavior;GO:0048871//multicellular organismal homeostasis;GO:0016358//dendrite development;GO:0015675//nickel cation transport;GO:0015691//cadmium ion transport;GO:0006818//hydrogen transport;GO:0015684//ferrous iron transport;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0055080//cation homeostasis;GO:0010039//response to iron ion;GO:0006915//apoptotic process;GO:0034612//response to tumor necrosis factor;GO:0001666//response to hypoxia;GO:0030218//erythrocyte differentiation;GO:0006829//zinc II ion transport;GO:0006825//copper ion transport;GO:0009593//detection of chemical stimulus;GO:0006979//response to oxidative stress;GO:0006828//manganese ion transport;GO:0044708//single-organism behavior;GO:0048871//multicellular organismal homeostasis "gi|148672142|gb|EDL04089.1|/0/solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2, isoform CRA_b, partial [Mus musculus]" 16797 1281 0.233333333 0.34 0.543142325 Up 0.185706495 Lat linker for activation of T cells K07362|1|5e-95|350|mmu:16797|linker for activation of T cells - - - - 545030 9681 0.236666667 0.343333333 0.536753408 Up 0.185706495 Wdfy4 WD repeat and FYVE domain containing 4 K18953|1|2e-79|302|bfo:BRAFLDRAFT_100614|factor associated with neutral sphingomyelinase activation - - - gi|225637485|ref|NP_001139494.1|/0/WD repeat- and FYVE domain-containing protein 4 [Mus musculus] 16600 3057 29.07666667 27.94333333 -0.05735776 Down 0.185452631 Klf4 Kruppel-like factor 4 (gut) K17846|1|0.0|815|mmu:16600|krueppel-like factor 4 GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0000785//chromatin "GO:0001134;GO:0008134//transcription factor binding;GO:0043566//structure-specific DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0046914//transition metal ion binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0019207//kinase regulator activity" GO:0016525//negative regulation of angiogenesis;GO:0034614//cellular response to reactive oxygen species;GO:0006915//apoptotic process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0043409//negative regulation of MAPK cascade;GO:0014070//response to organic cyclic compound;GO:0009791//post-embryonic development;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0008544//epidermis development;GO:0042036//negative regulation of cytokine biosynthetic process;GO:0033993//response to lipid;GO:0032682//negative regulation of chemokine production;GO:0070848//response to growth factor;GO:0043550//regulation of lipid kinase activity;GO:0014738;GO:0030154//cell differentiation;GO:0071417//cellular response to organonitrogen compound;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0034097//response to cytokine;GO:0022408//negative regulation of cell-cell adhesion;GO:0009887//organ morphogenesis gi|171543888|ref|NP_034767.2|/0/Krueppel-like factor 4 [Mus musculus] 22381 1018 14.00666667 13.36333333 -0.067833745 Down 0.185433826 Wbp5 WW domain binding protein 5 - - - - - 332110 1961 0.13 0.046666667 -1.478047297 Down 0.185358607 Mapk15 mitogen-activated protein kinase 15 K19603|1|0.0|864|mmu:332110|mitogen-activated protein kinase 15 [EC:2.7.11.24] GO:0043231//intracellular membrane-bounded organelle GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550 GO:0043627//response to estrogen;GO:0001932//regulation of protein phosphorylation;GO:0016567//protein ubiquitination;GO:0009896;GO:0006260//DNA replication "gi|148697564|gb|EDL29511.1|/0/mitogen-activated protein kinase 15, partial [Mus musculus]" 211329 3465 0.61 0.75 0.298081353 Up 0.185358607 Ncoa7 nuclear receptor coactivator 7 K12587|1|2e-44|184|bfo:BRAFLDRAFT_124886|exosome complex component MTR3 - GO:0051427//hormone receptor binding;GO:0003713//transcription coactivator activity GO:0044036;GO:0006366//transcription from RNA polymerase II promoter gi|162287054|ref|NP_001104737.1|/2.22719e-110/nuclear receptor coactivator 7 isoform 2 [Mus musculus] 243653 3268 2.876666667 2.63 -0.129335259 Down 0.18529279 Clec1a "C-type lectin domain family 1, member a" K10069|1|6e-144|514|mmu:243653|C-type lectin domain family 1 member A GO:0031224//intrinsic component of membrane GO:0005488//binding - gi|225543519|ref|NP_780735.2|/5.35507e-143/C-type lectin domain family 1 member A [Mus musculus] 55980 4185 2.763333333 3.016666667 0.12654569 Up 0.18529279 Impa1 inositol (myo)-1(or 4)-monophosphatase 1 K01092|1|3e-148|529|rno:83523|myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] GO:0043005//neuron projection;GO:0044297//cell body;GO:0043005//neuron projection;GO:0031981//nuclear lumen;GO:0044297//cell body GO:0043169//cation binding;GO:0052834//inositol monophosphate phosphatase activity;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0052834//inositol monophosphate phosphatase activity;GO:0042802//identical protein binding GO:0046488//phosphatidylinositol metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0019751//polyol metabolic process;GO:0007154//cell communication;GO:0010038//response to metal ion;GO:0046488//phosphatidylinositol metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0006020//inositol metabolic process;GO:0007154//cell communication gi|568920613|ref|XP_006530140.1|/1.78851e-154/PREDICTED: inositol monophosphatase 1 isoform X1 [Mus musculus] 98488 4764 2.783333333 2.536666667 -0.133879744 Down 0.18529279 Gtf3c3 "general transcription factor IIIC, polypeptide 3" K15201|1|0.0|1608|mmu:98488|general transcription factor 3C polypeptide 3 (transcription factor C subunit 4) - - - - 74022 3351.78 25.95666667 24.83666667 -0.063633563 Down 0.185255181 Glyr1 glyoxylate reductase 1 homolog (Arabidopsis) K00020|1|8e-73|278|dme:Dmel_CG4747|3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31];K18121|5|2e-57|227|spu:105438665|glyoxylate/succinic semialdehyde reductase [EC:1.1.1.79 1.1.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0042393//histone binding;GO:0003676//nucleic acid binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0036094//small molecule binding;GO:0048037//cofactor binding;GO:0003676//nucleic acid binding;GO:0042393//histone binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0048037//cofactor binding" GO:0006007//glucose catabolic process;GO:0044710;GO:0044710;GO:0006007//glucose catabolic process gi|471365484|ref|XP_004373283.1|/0/PREDICTED: putative oxidoreductase GLYR1 isoform X1 [Trichechus manatus latirostris] 70852 1550 0.346666667 0.24 -0.530514717 Down 0.185217571 Alkbh3os1 "alkB homolog 3, opposite strand 1" - - - - - 22217 4274 5.993333333 6.386666667 0.09170454 Up 0.185189364 Usp12 ubiquitin specific peptidase 12 K11842|1|0.0|761|mmu:22217|ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12] - GO:0019783//ubiquitin-like protein-specific protease activity;GO:0004175//endopeptidase activity;GO:0005488//binding;GO:0016790//thiolester hydrolase activity GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process gi|731494076|ref|XP_010592272.1|/0/PREDICTED: ubiquitin carboxyl-terminal hydrolase 12 isoform X1 [Loxodonta africana] 14629 3442 6.32 6.706666667 0.085671341 Up 0.185189364 Gclc "glutamate-cysteine ligase, catalytic subunit" K11204|1|0.0|1310|mmu:14629|glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2] GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0048037//cofactor binding;GO:0032550;GO:0016597//amino acid binding;GO:0046983//protein dimerization activity;GO:0046872//metal ion binding;GO:0016881//acid-amino acid ligase activity "GO:0006351//transcription, DNA-templated;GO:0003018;GO:0000096//sulfur amino acid metabolic process;GO:0042221//response to chemical;GO:0043066//negative regulation of apoptotic process;GO:0005996//monosaccharide metabolic process;GO:0003254//regulation of membrane depolarization;GO:0009064//glutamine family amino acid metabolic process;GO:0016567//protein ubiquitination;GO:0031331;GO:0006749//glutathione metabolic process;GO:0009719;GO:0006950//response to stress" gi|33468897|ref|NP_034425.1|/0/glutamate--cysteine ligase catalytic subunit [Mus musculus] 13199 3740 0.243333333 0.146666667 -0.73039294 Down 0.18509534 Ddn dendrin - GO:0030425//dendrite;GO:0032589//neuron projection membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043025//neuronal cell body - - gi|169234955|ref|NP_001013763.1|/0/dendrin [Mus musculus] 68159 1205 0.046666667 0.126666667 1.440572591 Up 0.185038926 Stx19 syntaxin 19 K08487|1|3e-143|510|mmu:68159|syntaxin 11 - GO:0005515//protein binding GO:0015031//protein transport gi|23956190|ref|NP_080864.1|/2.17597e-142/syntaxin-19 [Mus musculus] 279618 1222 0.126666667 0.046666667 -1.440572591 Down 0.185038926 Gm715 predicted gene 715 - - - - gi|409104114|ref|NP_001258477.1|/3.56631e-116/uncharacterized protein LOC279618 [Mus musculus] 213980 3267 0.02 0.093333333 2.222392421 Up 0.185010719 Fbxw10 F-box and WD-40 domain protein 10 K10266|1|0.0|1959|mmu:213980|F-box and WD-40 domain protein 10 - - - gi|612339345|ref|NP_001278370.1|/0/F-box/WD repeat-containing protein 10 isoform 1 [Mus musculus] 70605 2508.82 2.206666667 1.986666667 -0.151518886 Down 0.184963707 Zdhhc24 "zinc finger, DHHC domain containing 24" K18932|1|3e-90|335|mmu:70605|palmitoyltransferase [EC:2.3.1.225] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0016740//transferase activity;GO:0046914//transition metal ion binding;GO:0016740//transferase activity;GO:0046914//transition metal ion binding - "gi|148701129|gb|EDL33076.1|/9.98966e-90/zinc finger, DHHC domain containing 24, isoform CRA_a, partial [Mus musculus]" 76800 5151 2.253333333 2.036666667 -0.145850866 Down 0.184963707 Usp42 ubiquitin specific peptidase 42 K11855|1|0.0|2410|mmu:76800|ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12] - GO:0019783//ubiquitin-like protein-specific protease activity GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process;GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|116686116|ref|NP_084025.2|/0/ubiquitin carboxyl-terminal hydrolase 42 [Mus musculus] 231042 2909 3.613333333 3.91 0.113838257 Up 0.184944902 Nupl2 nucleoporin like 2 K14321|1|0.0|707|mmu:231042|nucleoporin-like protein 2 GO:0005635//nuclear envelope GO:0046914//transition metal ion binding GO:0050658//RNA transport;GO:0045184//establishment of protein localization gi|254540171|ref|NP_694732.3|/0/nucleoporin-like protein 2 [Mus musculus] 226499 3255 4.036666667 3.736666667 -0.111412587 Down 0.184944902 BC003331 cDNA sequence BC003331 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding - "gi|148707534|gb|EDL39481.1|/0/cDNA sequence BC003331, isoform CRA_b, partial [Mus musculus]" 70208 4946 4.2 3.896666667 -0.108148804 Down 0.184944902 Med23 mediator complex subunit 23 K15166|1|0.0|2764|mmu:70208|mediator of RNA polymerase II transcription subunit 23 - - - gi|37360288|dbj|BAC98122.1|/0/mKIAA1216 protein [Mus musculus] 75553 3506.95 25.51333333 24.41333333 -0.06358211 Down 0.184916695 Zc3h14 zinc finger CCCH type containing 14 K15193|1|4e-17|92.8|cel:CELE_Y61A9LA.8|protein SPT2 GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding - "gi|148686978|gb|EDL18925.1|/0/zinc finger CCCH type containing 14, isoform CRA_b, partial [Mus musculus]" 67903 1632 25.34333333 24.24333333 -0.064018215 Down 0.184916695 Gipc1 "GIPC PDZ domain containing family, member 1" K20056|1|4e-164|580|cge:100753328|PDZ domain-containing protein GIPC GO:0005829//cytosol;GO:0030425//dendrite;GO:0012505//endomembrane system;GO:0030136//clathrin-coated vesicle GO:0008047//enzyme activator activity;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006835//dicarboxylic acid transport;GO:0006886//intracellular protein transport;GO:0031330;GO:0010608//posttranscriptional regulation of gene expression;GO:0050804//modulation of synaptic transmission;GO:0016477//cell migration gi|564395025|ref|XP_006255373.1|/4.76907e-165/PREDICTED: PDZ domain-containing protein GIPC1 isoform X2 [Rattus norvegicus] 24105 2353.71 25.85 24.75 -0.062735755 Down 0.184916695 Rbck1 RanBP-type and C3HC4-type zinc finger containing 1 K10630|1|0.0|968|mmu:24105|RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.27] GO:0000151//ubiquitin ligase complex;GO:0000151//ubiquitin ligase complex "GO:0032182//ubiquitin-like protein binding;GO:0046914//transition metal ion binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019901//protein kinase binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0043566//structure-specific DNA binding;GO:0032182//ubiquitin-like protein binding;GO:0046914//transition metal ion binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019901//protein kinase binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0043566//structure-specific DNA binding" GO:0000209//protein polyubiquitination;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0000209//protein polyubiquitination;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0042345//regulation of NF-kappaB import into nucleus "gi|148674011|gb|EDL05958.1|/0/RanBP-type and C3HC4-type zinc finger containing 1, isoform CRA_a, partial [Mus musculus]" 60345 1896 1.443333333 1.26 -0.195980791 Down 0.184879085 Nrip2 nuclear receptor interacting protein 2 K13215|1|6e-114|414|rno:689619|nuclear receptor-interacting protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0004175//endopeptidase activity;GO:0005488//binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0019538//protein metabolic process;GO:0006366//transcription from RNA polymerase II promoter gi|247269066|ref|NP_068363.2|/1.54056e-117/nuclear receptor-interacting protein 2 isoform 2 [Mus musculus] 71764 4334 7.9 8.363333333 0.082225412 Up 0.184832073 C2cd2l C2 calcium-dependent domain containing 2-like - GO:0031224//intrinsic component of membrane - - gi|88900515|ref|NP_082185.2|/0/C2 domain-containing protein 2-like [Mus musculus] 330662 6815 7.526666667 7.983333333 0.08498017 Up 0.184832073 Dock1 dedicator of cytokinesis 1 K13708|1|0.0|3465|mmu:330662|dedicator of cytokinesis protein 1 GO:0044444//cytoplasmic part GO:0030695//GTPase regulator activity;GO:0008047//enzyme activator activity;GO:0019904//protein domain specific binding GO:0043087//regulation of GTPase activity;GO:0006909//phagocytosis;GO:0007166//cell surface receptor signaling pathway;GO:0007599//hemostasis;GO:0012501//programmed cell death;GO:0048870//cell motility;GO:0006935//chemotaxis gi|88853584|ref|NP_001028592.1|/0/dedicator of cytokinesis protein 1 [Mus musculus] 103136 2579 8.04 8.5 0.08026734 Up 0.184832073 Pwp1 "PWP1 homolog, endonuclein" K14791|1|0.0|943|mmu:103136|periodic tryptophan protein 1 - - - - 11772 4639 27.33666667 26.24666667 -0.058703125 Down 0.184813269 Ap2a2 "adaptor-related protein complex 2, alpha 2 subunit" K11824|1|0.0|1754|mmu:11772|AP-2 complex subunit alpha - - - - 76893 2127 24.20666667 25.29666667 0.063542865 Up 0.184813269 Cers2 ceramide synthase 2 K04710|1|0.0|732|mmu:76893|ceramide synthetase [EC:2.3.1.24];K14537|3|0.0|705|ocu:100355139|nuclear GTP-binding protein GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0005635//nuclear envelope GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0016410//N-acyltransferase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0016410//N-acyltransferase activity "GO:0006796//phosphate-containing compound metabolic process;GO:0006672//ceramide metabolic process;GO:0006351//transcription, DNA-templated;GO:0006796//phosphate-containing compound metabolic process;GO:0006672//ceramide metabolic process;GO:0006351//transcription, DNA-templated" gi|22095015|ref|NP_084065.1|/0/ceramide synthase 2 [Mus musculus] 237859 3132 3.413333333 3.143333333 -0.118886039 Down 0.184794464 Nsrp1 nuclear speckle regulatory protein 1 K13206|1|0.0|839|mmu:237859|coiled-coil domain-containing protein 55 - - - - 233011 3260 3.136666667 3.406666667 0.119128568 Up 0.184794464 Itpkc "inositol 1,4,5-trisphosphate 3-kinase C" K00911|1|0.0|1276|mmu:233011|1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127] GO:0043231//intracellular membrane-bounded organelle GO:0051766//inositol trisphosphate kinase activity;GO:0005515//protein binding;GO:0032550 GO:0006796//phosphate-containing compound metabolic process gi|31712006|ref|NP_853624.1|/0/inositol-trisphosphate 3-kinase C [Mus musculus] 68524 7589 3.493333333 3.22 -0.117543623 Down 0.184794464 Wipf2 "WAS/WASL interacting protein family, member 2" K19475|1|5e-139|499|mmu:68524|WAS/WASL-interacting protein - - - gi|37537556|ref|NP_922922.1|/4.42469e-138/WAS/WASL-interacting protein family member 2 [Mus musculus] 68588 1164 0.13 0.05 -1.378511623 Down 0.18473805 Cthrc1 collagen triple helix repeat containing 1 "K04828|1|8e-38|160|bfo:BRAFLDRAFT_107688|acid-sensing ion channel 2;K13649|2|1e-16|89.7|bfo:BRAFLDRAFT_123559|folate receptor;K06823|4|8e-07|57.4|xma:102216429|collagen, type XVIII, alpha" GO:0044424;GO:0005578//proteinaceous extracellular matrix GO:0001664//G-protein coupled receptor binding GO:0042249//establishment of planar polarity of embryonic epithelium;GO:0001649//osteoblast differentiation;GO:0043393//regulation of protein binding;GO:0048870//cell motility;GO:0030178//negative regulation of Wnt signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0030030//cell projection organization;GO:0035567//non-canonical Wnt signaling pathway;GO:0048598//embryonic morphogenesis gi|149066481|gb|EDM16354.1|/8.12391e-139/collagen triple helix repeat containing 1 [Rattus norvegicus] 70998 4420 1.076666667 0.92 -0.226865898 Down 0.18470044 Phf6 PHD finger protein 6 K18494|1|1e-22|112|fab:101812936|histone-lysine N-methyltransferase SETDB2 [EC:2.1.1.43];K19998|5|4e-11|73.9|apla:101795279|sec1 family domain-containing protein 1 - - - - 16428 1276 0.913333333 1.07 0.228397404 Up 0.18470044 Itk IL2 inducible T cell kinase K07363|1|0.0|1277|mmu:16428|IL2-inducible T-cell kinase [EC:2.7.10.2] GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0043169//cation binding;GO:0032550;GO:0008289//lipid binding;GO:0004713//protein tyrosine kinase activity;GO:0043169//cation binding;GO:0032550;GO:0008289//lipid binding;GO:0004713//protein tyrosine kinase activity;GO:0043169//cation binding;GO:0032550;GO:0008289//lipid binding;GO:0004713//protein tyrosine kinase activity;GO:0043169//cation binding;GO:0032550;GO:0008289//lipid binding;GO:0004713//protein tyrosine kinase activity;GO:0043169//cation binding;GO:0032550;GO:0008289//lipid binding;GO:0004713//protein tyrosine kinase activity GO:0010863//positive regulation of phospholipase C activity;GO:0006464//cellular protein modification process;GO:0046632//alpha-beta T cell differentiation;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0001816//cytokine production;GO:0010863//positive regulation of phospholipase C activity;GO:0006464//cellular protein modification process;GO:0046632//alpha-beta T cell differentiation;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0001816//cytokine production;GO:0010863//positive regulation of phospholipase C activity;GO:0006464//cellular protein modification process;GO:0046632//alpha-beta T cell differentiation;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0001816//cytokine production;GO:0010863//positive regulation of phospholipase C activity;GO:0006464//cellular protein modification process;GO:0046632//alpha-beta T cell differentiation;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0001816//cytokine production;GO:0010863//positive regulation of phospholipase C activity;GO:0006464//cellular protein modification process;GO:0046632//alpha-beta T cell differentiation;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0001816//cytokine production "gi|148701875|gb|EDL33822.1|/3.63074e-159/IL2-inducible T-cell kinase, isoform CRA_b, partial [Mus musculus]" 320832 1232 0.05 0.126666667 1.341036918 Up 0.184559404 Sirpb1a signal-regulatory protein beta 1A K06551|1|0.0|741|mmu:320832|signal-regulatory protein alpha/beta1/gamma GO:0016020//membrane - GO:0006909//phagocytosis;GO:0007165//signal transduction gi|50872163|ref|NP_001002898.1|/0/signal-regulatory protein beta 1 [Mus musculus] 56191 7044.61 0.05 0.126666667 1.341036918 Up 0.184559404 Tro trophinin K12464|1|6e-80|301|myb:102256960|melanoma-associated antigen D1 GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044424;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0022610;GO:0016049//cell growth;GO:0022610;GO:0016049//cell growth;GO:0044763;GO:0022610;GO:0016049//cell growth gi|755566650|ref|XP_011246150.1|/0/PREDICTED: trophinin isoform X3 [Mus musculus] 21810 2678 13.29333333 13.91333333 0.065765191 Up 0.184559404 Tgfbi "transforming growth factor, beta induced" K19519|1|0.0|1236|mmu:21810|transforming growth factor-beta-induced protein GO:0031988//membrane-bounded vesicle;GO:0005578//proteinaceous extracellular matrix GO:0005488//binding GO:0043062//extracellular structure organization;GO:0022610 gi|6678321|ref|NP_033395.1|/0/transforming growth factor-beta-induced protein ig-h3 precursor [Mus musculus] 71421 1022 0.053333333 0.136666667 1.357552005 Up 0.184559404 Amtn amelotin - - - - - 66863 3108 12.02333333 12.64 0.072159541 Up 0.184559404 Lztr1 "leucine-zipper-like transcriptional regulator, 1" K20285|1|8e-21|105|bfo:BRAFLDRAFT_127137|Rab9 effector protein with kelch motifs - - - gi|27229001|ref|NP_080084.2|/0/leucine-zipper-like transcriptional regulator 1 [Mus musculus] 26914 1966.92 26.25666667 25.18666667 -0.060023574 Down 0.184512392 H2afy "H2A histone family, member Y" K11251|1|1e-172|608|mmu:26914|histone H2A - - - - 171508 2078 24.15666667 25.22666667 0.062528194 Up 0.184512392 Creld1 cysteine-rich with EGF-like domains 1 K17675|1|1e-47|193|tsp:Tsp_02850|ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:3.6.4.13];K19013|3|1e-19|101|rno:282580|stabilin-2 GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding - gi|19527148|ref|NP_598691.1|/0/cysteine-rich with EGF-like domain protein 1 precursor [Mus musculus] 18044 3641 4.996666667 4.666666667 -0.098573556 Down 0.184493588 Nfya nuclear transcription factor-Y alpha "K08064|1|6e-73|278|pale:102885407|nuclear transcription factor Y, alpha" GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding "GO:0006366//transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated" gi|183782|gb|AAA35950.1|/5.73287e-72/CCAAT-binding protein [Homo sapiens] 72938 559 4.723333333 4.393333333 -0.104489388 Down 0.184493588 Hspb11 "heat shock protein family B (small), member 11" K19369|1|1e-77|290|mmu:72938|heat shock protein beta-11 GO:0030990//intraciliary transport particle - GO:0022610;GO:0050896//response to stimulus gi|564352020|ref|XP_006238587.1|/1.34368e-78/PREDICTED: intraflagellar transport protein 25 homolog isoform X2 [Rattus norvegicus] 111173 7775.04 5.08 4.753333333 -0.095888921 Down 0.184493588 Erc1 ELKS/RAB6-interacting/CAST family member 1 K16072|1|0.0|1512|rno:266806|ELKS/RAB6-interacting/CAST family member 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0017016//Ras GTPase binding;GO:0019904//protein domain specific binding GO:0016192//vesicle-mediated transport;GO:0006468//protein phosphorylation;GO:0045184//establishment of protein localization gi|13445784|gb|AAK26381.1|AF340028_1/0/Rab6-interacting protein 2 isoform A [Mus musculus] 71877 2208 0.163333333 0.263333333 0.689070904 Up 0.184484185 Efhc1 EF-hand domain (C-terminal) containing 1 - - - - - 28105 4555 0.256666667 0.366666667 0.514573173 Up 0.184484185 Trim36 tripartite motif-containing 36 K12013|1|0.0|1494|mmu:28105|tripartite motif-containing protein 36 [EC:2.3.2.27] GO:0031982//vesicle;GO:0043232;GO:0031982//vesicle;GO:0043232 GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0007338//single fertilization;GO:0007338//single fertilization gi|283945596|ref|NP_001164326.1|/0/E3 ubiquitin-protein ligase Trim36 isoform 2 [Mus musculus] 75033 3061 0.36 0.253333333 -0.506959989 Down 0.184484185 Mei4 meiotic double-stranded break formation protein 4 - - - - - 12018 2017 27.67 26.61 -0.056354134 Down 0.184352552 Bak1 BCL2-antagonist/killer 1 K14021|1|4e-117|424|mmu:12018|Bcl-2 homologous antagonist/killer GO:0031306//intrinsic component of mitochondrial outer membrane;GO:0016021//integral component of membrane GO:0042802//identical protein binding;GO:0019904//protein domain specific binding;GO:0043169//cation binding;GO:0046983//protein dimerization activity GO:0010467//gene expression;GO:0010822//positive regulation of mitochondrion organization;GO:0070227;GO:0009636//response to toxic substance;GO:0031016//pancreas development;GO:0035107//appendage morphogenesis;GO:0002260//lymphocyte homeostasis;GO:0034976//response to endoplasmic reticulum stress;GO:0009612//response to mechanical stimulus;GO:0002339;GO:0042391//regulation of membrane potential;GO:0009967//positive regulation of signal transduction;GO:0010522//regulation of calcium ion transport into cytosol;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0001933//negative regulation of protein phosphorylation;GO:0006508//proteolysis;GO:0009411//response to UV;GO:0048771//tissue remodeling;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0010212//response to ionizing radiation;GO:0030540//female genitalia development;GO:0034220//ion transmembrane transport;GO:0000302//response to reactive oxygen species;GO:0043393//regulation of protein binding;GO:0008637//apoptotic mitochondrial changes;GO:0007049//cell cycle;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0031077//post-embryonic camera-type eye development;GO:0006839//mitochondrial transport;GO:0051707//response to other organism;GO:0097305//response to alcohol;GO:0009887//organ morphogenesis gi|111955302|ref|NP_031549.2|/3.15251e-116/bcl-2 homologous antagonist/killer [Mus musculus] 207393 4877 0.256666667 0.16 -0.68182404 Down 0.184324345 Elfn2 "leucine rich repeat and fibronectin type III, extracellular 2" K17568|1|0.0|1477|mmu:207393|protein phosphatase 1 regulatory subunit 29 GO:0031224//intrinsic component of membrane GO:0019899//enzyme binding;GO:0019212//phosphatase inhibitor activity GO:0010921//regulation of phosphatase activity;GO:0044092//negative regulation of molecular function gi|62990174|ref|NP_898964.2|/0/protein phosphatase 1 regulatory subunit 29 precursor [Mus musculus] 69479 2740 0.62 0.756666667 0.287389676 Up 0.184277333 1700029J07Rik RIKEN cDNA 1700029J07 gene - - - - gi|75677532|ref|NP_001028320.1|/5.85205e-164/UPF0602 protein C4orf47 homolog [Mus musculus] 236604 2858 0.793333333 0.65 -0.28748745 Down 0.184277333 Pisd-ps1 "phosphatidylserine decarboxylase, pseudogene 1" K01613|1|3e-146|521|myd:102754521|phosphatidylserine decarboxylase [EC:4.1.1.65] - - - "gi|148705450|gb|EDL37397.1|/1.20221e-159/mCG2531, isoform CRA_a [Mus musculus]" 108811 1780 0.62 0.756666667 0.287389676 Up 0.184277333 Ccdc122 coiled-coil domain containing 122 K11168|1|2e-49|199|cmk:103177522|dehydrogenase/reductase SDR family member 12 [EC:1.1.-.-];K11499|2|4e-11|72.4|mdo:100023442|centromere protein F;K20478|3|4e-10|68.9|dre:557772|golgin subfamily B member 1 - - - "gi|148703850|gb|EDL35797.1|/1.26519e-169/RIKEN cDNA 4933415L06, isoform CRA_c, partial [Mus musculus]" 329165 5636.14 2.353333333 2.586666667 0.136388469 Up 0.18426793 Abi2 abl-interactor 2 K05751|1|0.0|723|mmu:329165|abl interactor 2 GO:0043005//neuron projection;GO:0043232;GO:0031252//cell leading edge;GO:0005911//cell-cell junction;GO:0044444//cytoplasmic part;GO:0043005//neuron projection;GO:0043232;GO:0031252//cell leading edge;GO:0005911//cell-cell junction;GO:0044444//cytoplasmic part;GO:0043005//neuron projection;GO:0043232;GO:0031252//cell leading edge;GO:0005911//cell-cell junction;GO:0044444//cytoplasmic part GO:0044389//ubiquitin-like protein ligase binding;GO:0019904//protein domain specific binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0019904//protein domain specific binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0019904//protein domain specific binding GO:0001654//eye development;GO:0048870//cell motility;GO:0031175//neuron projection development;GO:0044708//single-organism behavior;GO:0001654//eye development;GO:0048870//cell motility;GO:0031175//neuron projection development;GO:0044708//single-organism behavior;GO:0001654//eye development;GO:0048870//cell motility;GO:0031175//neuron projection development;GO:0044708//single-organism behavior gi|310688887|ref|NP_001185500.1|/0/abl interactor 2 isoform 2 [Mus musculus] 78618 6493 2.326666667 2.556666667 0.135999541 Up 0.18426793 Acap2 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 2" "K12489|1|0.0|1484|mmu:78618|Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein" - GO:0008047//enzyme activator activity;GO:0046914//transition metal ion binding;GO:0008289//lipid binding GO:0044763;GO:0032012//regulation of ARF protein signal transduction gi|37359746|dbj|BAC97851.1|/0/mKIAA0041 protein [Mus musculus] 55947 4074 2.453333333 2.226666667 -0.139857664 Down 0.18426793 Dclre1a DNA cross-link repair 1A K15340|1|0.0|2028|mmu:55947|DNA cross-link repair 1A protein - - - - 67276 5067 2.193333333 2.42 0.141881964 Up 0.18426793 Eri1 exoribonuclease 1 K18416|1|0.0|639|mmu:67276|3'-5' exoribonuclease 1 [EC:3.1.-.-] GO:0031981//nuclear lumen;GO:0030529//intracellular ribonucleoprotein complex GO:0043169//cation binding;GO:0043021//ribonucleoprotein complex binding;GO:0036002//pre-mRNA binding;GO:0004527//exonuclease activity GO:0016458//gene silencing;GO:0006364//rRNA processing;GO:0000956//nuclear-transcribed mRNA catabolic process gi|165905605|ref|NP_080343.4|/2.33181e-180/3'-5' exoribonuclease 1 [Mus musculus] 320234 2951 2.376666667 2.61 0.135110231 Up 0.18426793 Ccdc66 coiled-coil domain containing 66 - - - - gi|118200350|ref|NP_796085.3|/0/coiled-coil domain-containing protein 66 [Mus musculus] 243905 7195.54 1.853333333 2.066666667 0.157183333 Up 0.184230321 Zfp568 zinc finger protein 568 K09228|1|0.0|1397|mmu:243905|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0043169//cation binding;GO:0043169//cation binding GO:0003401//axis elongation;GO:0014022;GO:0001892//embryonic placenta development;GO:0007154//cell communication;GO:0003401//axis elongation;GO:0014022;GO:0001892//embryonic placenta development;GO:0007154//cell communication;GO:0003401//axis elongation;GO:0014022;GO:0001892//embryonic placenta development;GO:0007154//cell communication gi|268607554|ref|NP_001028527.2|/0/zinc finger protein 568 isoform 1 [Mus musculus] 21924 703 4253.403333 4113.036667 -0.048413733 Down 0.184173907 Tnnc1 "troponin C, cardiac/slow skeletal" "K05865|1|1e-80|301|ngi:103749000|troponin C, slow skeletal and cardiac muscles" GO:0005865//striated muscle thin filament GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding GO:0006941//striated muscle contraction;GO:0032971//regulation of muscle filament sliding;GO:0003208//cardiac ventricle morphogenesis;GO:0009118//regulation of nucleoside metabolic process;GO:0010035//response to inorganic substance "gi|148692849|gb|EDL24796.1|/8.23748e-82/troponin C, cardiac/slow skeletal, partial [Mus musculus]" 110323 505 1674.57 1621.216667 -0.046713773 Down 0.18407048 Cox6b1 "cytochrome c oxidase, subunit VIb polypeptide 1" K02267|1|5e-48|191|rno:688869|cytochrome c oxidase subunit 6b GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0015002//heme-copper terminal oxidase activity GO:0044710 gi|13385090|ref|NP_079904.1|/3.33399e-47/cytochrome c oxidase subunit 6B1 [Mus musculus] 214137 5133 13.21333333 12.6 -0.068570728 Down 0.184032871 Arhgap29 Rho GTPase activating protein 29 "K02649|1|4e-25|120|bfo:BRAFLDRAFT_91712|phosphoinositide-3-kinase, regulatory subunit;K10360|2|5e-24|117|tca:656579|myosin IX;K20315|3|6e-24|116|loa:LOAG_12329|Rho GTPase-activating protein 21/23" GO:0044464 GO:0043169//cation binding GO:0007165//signal transduction gi|33563303|ref|NP_766113.1|/0/rho GTPase-activating protein 29 [Mus musculus] 71752 4551 13.65666667 13.05 -0.065555585 Down 0.184032871 Gtf3c2 "general transcription factor IIIC, polypeptide 2, beta" K15200|1|0.0|1622|mmu:71752|general transcription factor 3C polypeptide 2 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|37359730|dbj|BAC97843.1|/0/mKIAA0011 protein [Mus musculus] 231915 3481.91 7.633333333 8.086666667 0.083231952 Up 0.183985859 Uspl1 ubiquitin specific peptidase like 1 - GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body GO:0016929//SUMO-specific protease activity;GO:0032182//ubiquitin-like protein binding;GO:0016929//SUMO-specific protease activity;GO:0032182//ubiquitin-like protein binding;GO:0016929//SUMO-specific protease activity;GO:0032182//ubiquitin-like protein binding;GO:0016929//SUMO-specific protease activity;GO:0032182//ubiquitin-like protein binding;GO:0016929//SUMO-specific protease activity;GO:0032182//ubiquitin-like protein binding;GO:0016929//SUMO-specific protease activity;GO:0032182//ubiquitin-like protein binding;GO:0016929//SUMO-specific protease activity;GO:0032182//ubiquitin-like protein binding GO:0019941//modification-dependent protein catabolic process;GO:0030575//nuclear body organization;GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process;GO:0030575//nuclear body organization;GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process;GO:0030575//nuclear body organization;GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process;GO:0030575//nuclear body organization;GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process;GO:0030575//nuclear body organization;GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process;GO:0030575//nuclear body organization;GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process;GO:0030575//nuclear body organization;GO:0070646//protein modification by small protein removal "gi|148673913|gb|EDL05860.1|/0/mCG145048, isoform CRA_a, partial [Mus musculus]" 57321 3599 7.663333333 8.116666667 0.082915306 Up 0.183985859 Terf2ip "telomeric repeat binding factor 2, interacting protein" K11113|1|0.0|708|mmu:57321|telomeric repeat-binding factor 2-interacting protein 1 GO:0000782//telomere cap complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003676//nucleic acid binding GO:0045910//negative regulation of DNA recombination;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0034502//protein localization to chromosome;GO:0016233//telomere capping;GO:0007249//I-kappaB kinase/NF-kappaB signaling "gi|148679582|gb|EDL11529.1|/0/telomeric repeat binding factor 2, interacting protein, isoform CRA_b, partial [Mus musculus]" 19246 4213 7.86 8.31 0.080319165 Up 0.183985859 Ptpn1 "protein tyrosine phosphatase, non-receptor type 1" K05696|1|0.0|792|mmu:19246|tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48] GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0031982//vesicle;GO:0031090//organelle membrane GO:0019900//kinase binding;GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0004721//phosphoprotein phosphatase activity GO:0008286//insulin receptor signaling pathway;GO:0006470//protein dephosphorylation;GO:0030036//actin cytoskeleton organization;GO:0006897//endocytosis;GO:0006984//ER-nucleus signaling pathway gi|133505845|ref|NP_035331.3|/0/tyrosine-protein phosphatase non-receptor type 1 [Mus musculus] 110639 3716.18 5.973333333 5.593333333 -0.094827922 Down 0.183976456 Prps2 phosphoribosyl pyrophosphate synthetase 2 K00948|1|1e-176|623|mmu:110639|ribose-phosphate pyrophosphokinase [EC:2.7.6.1] - - - - 235036 1671 5.72 6.096666667 0.092005522 Up 0.183976456 Ppan peter pan homolog (Drosophila) K14859|1|0.0|902|mmu:235036|ribosome biogenesis protein SSF1/2 GO:0043231//intracellular membrane-bounded organelle - - gi|255683374|ref|NP_663585.2|/0/suppressor of SWI4 1 homolog [Mus musculus] 103724 1929 5.973333333 6.353333333 0.088977482 Up 0.183976456 Tbc1d10a "TBC1 domain family, member 10a" K19944|1|0.0|1015|mmu:103724|TBC1 domain family member 10 - - - - 100502942 907 5.846666667 6.223333333 0.09007318 Up 0.183976456 Gm4814 predicted gene 4814 - - - - gi|26341380|dbj|BAC34352.1|/1.44638e-59/unnamed protein product [Mus musculus] 76757 4514 27.44 26.40333333 -0.055560405 Down 0.183967054 Trdn triadin - GO:0033017//sarcoplasmic reticulum membrane GO:0005488//binding GO:0010033//response to organic substance;GO:0051924//regulation of calcium ion transport;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0035914//skeletal muscle cell differentiation gi|226437651|ref|NP_084002.2|/0/triadin [Mus musculus] 75138 1020 0.056666667 0.136666667 1.270089163 Up 0.183948249 4930526L06Rik RIKEN cDNA 4930526L06 gene - - - - gi|148709464|gb|EDL41410.1|/5.4249e-24/mCG148465 [Mus musculus] 100503580 4789 0.06 0.143333333 1.256339753 Up 0.183948249 Gm19782 "predicted gene, 19782" - - - - gi|807677|gb|AAA66456.1|/3.4481e-08/unknown protein [Rattus norvegicus] 18511 4334 0.056666667 0.14 1.304854582 Up 0.183948249 Pax9 paired box 9 K09382|1|0.0|679|mmu:18511|paired box protein 1/9 - - - - 114644 3224 0.363333333 0.483333333 0.411724765 Up 0.183929445 Slc13a3 "solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3" "K14445|1|0.0|965|mmu:114644|solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5" GO:0031224//intrinsic component of membrane GO:0015142//tricarboxylic acid transmembrane transporter activity;GO:0015556//C4-dicarboxylate transmembrane transporter activity;GO:0017153//sodium:dicarboxylate symporter activity GO:0006814//sodium ion transport;GO:0044763;GO:0015744//succinate transport;GO:0006842//tricarboxylic acid transport gi|16905091|ref|NP_473396.1|/0/solute carrier family 13 member 3 [Mus musculus] 402767 1130 0.483333333 0.363333333 -0.411724765 Down 0.183929445 A830052D11Rik RIKEN cDNA A830052D11 gene - - - - - 54670 6440 0.373333333 0.496666667 0.411813598 Up 0.183929445 Atp8b1 "ATPase, class I, type 8B, member 1" K01530|1|0.0|2345|mmu:54670|phospholipid-translocating ATPase [EC:3.6.3.1] - - - gi|80861460|ref|NP_001001488.2|/0/phospholipid-transporting ATPase IC [Mus musculus] 72672 6840 0.386666667 0.51 0.399406848 Up 0.18391064 Zfp518a zinc finger protein 518A K09228|1|2e-18|98.6|bfo:BRAFLDRAFT_194472|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|133507240|ref|NP_082595.1|/0/zinc finger protein 518A [Mus musculus] 224022 3231 0.513333333 0.39 -0.396421821 Down 0.18391064 Slc7a4 "solute carrier family 7 (cationic amino acid transporter, y+ system), member 4" "K13866|1|0.0|1003|mmu:224022|solute carrier family 7 (cationic amino acid transporter), member 4" GO:0031224//intrinsic component of membrane GO:0046943//carboxylic acid transmembrane transporter activity GO:0046942//carboxylic acid transport gi|568995136|ref|XP_006522101.1|/0/PREDICTED: cationic amino acid transporter 4 isoform X1 [Mus musculus] 15481 2104 943.3 912.2866667 -0.048229436 Down 0.183901237 Hspa8 heat shock protein 8 K03283|1|0.0|1129|cjc:100389824|heat shock 70kDa protein 1/8 GO:0031981//nuclear lumen;GO:0044297//cell body;GO:0030665//clathrin-coated vesicle membrane;GO:0048770;GO:0043234//protein complex;GO:0042995//cell projection;GO:0030529//intracellular ribonucleoprotein complex GO:0032550;GO:0005515//protein binding;GO:0016887//ATPase activity "GO:0006351//transcription, DNA-templated;GO:0035966//response to topologically incorrect protein;GO:0006396//RNA processing;GO:0048193//Golgi vesicle transport;GO:0009154//purine ribonucleotide catabolic process;GO:0001505//regulation of neurotransmitter levels;GO:0051084//'de novo' posttranslational protein folding;GO:0007049//cell cycle" gi|676282501|gb|KFO35963.1|/0/Heat shock cognate 71 kDa protein [Fukomys damarensis] 56188 573.59 837.3733333 808.7166667 -0.050236631 Down 0.183882433 Fxyd1 FXYD domain-containing ion transport regulator 1 K13360|1|5e-28|126|mmu:56188|FXYD domain-containing ion transport regulator 1 GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0003012//muscle system process;GO:0006811//ion transport;GO:0006875//cellular metal ion homeostasis;GO:0003012//muscle system process;GO:0006811//ion transport;GO:0006875//cellular metal ion homeostasis;GO:0003012//muscle system process;GO:0006811//ion transport;GO:0006875//cellular metal ion homeostasis;GO:0003012//muscle system process;GO:0006811//ion transport;GO:0006875//cellular metal ion homeostasis "gi|148692014|gb|EDL23961.1|/8.85634e-68/FXYD domain-containing ion transport regulator 1, isoform CRA_d, partial [Mus musculus]" 14683 1706.67 780.22 808 0.050474312 Up 0.183863628 Gnas "GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus" K04632|1|0.0|711|mmu:14683|guanine nucleotide-binding protein G(s) subunit alpha - - - gi|117959928|ref|NP_001070978.1|/0/protein GNAS isoform GNASS [Mus musculus] 72341 2082 0.78 0.93 0.253756592 Up 0.183844823 Elp6 elongator acetyltransferase complex subunit 6 - GO:0043234//protein complex - "GO:0016477//cell migration;GO:0006351//transcription, DNA-templated" gi|145587074|ref|NP_001074850.1|/1.41579e-135/elongator complex protein 6 [Mus musculus] 72345 8476 0.93 0.783333333 -0.247604365 Down 0.183844823 Amer1 APC membrane recruitment 1 K19407|1|0.0|1920|mmu:72345|APC membrane recruitment protein 1 - - - - 330361 3375 0.8 0.953333333 0.252980741 Up 0.183844823 Gcfc2 GC-rich sequence DNA binding factor 2 K09061|1|0.0|1276|mmu:330361|GC-rich sequence DNA-binding factor - - - gi|70608163|ref|NP_808552.2|/0/GC-rich sequence DNA-binding factor 2 [Mus musculus] 68473 3171 0.933333333 0.786666667 -0.246639968 Down 0.183844823 Mob1b MOB kinase activator 1B K06685|1|1e-124|450|gga:422647|MOB kinase activator 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0043169//cation binding;GO:0008047//enzyme activator activity;GO:0019899//enzyme binding" GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0044093 gi|971393650|ref|XP_015131897.1|/1.19788e-123/PREDICTED: MOB kinase activator 1B [Gallus gallus] 12864 527 695.91 720.9466667 0.050991799 Up 0.183816616 Cox6c cytochrome c oxidase subunit VIc K02268|1|9e-36|151|mmu:12864|cytochrome c oxidase subunit 6c GO:0031224//intrinsic component of membrane;GO:0005746//mitochondrial respiratory chain GO:0015002//heme-copper terminal oxidase activity GO:0006818//hydrogen transport;GO:0006811//ion transport;GO:0044710 gi|16716343|ref|NP_444301.1|/5.78821e-35/cytochrome c oxidase subunit 6C [Mus musculus] 54196 1793 26.39666667 27.42333333 0.055048183 Up 0.183807214 Pabpn1 "poly(A) binding protein, nuclear 1" K14396|1|2e-93|345|mmu:54196|polyadenylate-binding protein 2 GO:0032991//macromolecular complex;GO:0031981//nuclear lumen GO:0003729//mRNA binding;GO:0036094//small molecule binding GO:0000377;GO:0003012//muscle system process;GO:0031124//mRNA 3'-end processing;GO:0006406//mRNA export from nucleus;GO:0019054//modulation by virus of host process;GO:0006366//transcription from RNA polymerase II promoter gi|9506945|ref|NP_062275.1|/2.09243e-92/polyadenylate-binding protein 2 [Mus musculus] 12064 4009 1.23 1.06 -0.214594051 Down 0.183807214 Bdnf brain derived neurotrophic factor K04355|1|8e-134|481|mmu:12064|brain-derived neurotrophic factor GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle;GO:0030136//clathrin-coated vesicle GO:0005167;GO:0005167;GO:0005167;GO:0005167;GO:0005167;GO:0005167;GO:0005167;GO:0005167;GO:0005167;GO:0005167;GO:0005167 GO:0033555//multicellular organismal response to stress;GO:0043066//negative regulation of apoptotic process;GO:0006835//dicarboxylic acid transport;GO:0043583//ear development;GO:0014706//striated muscle tissue development;GO:0007405//neuroblast proliferation;GO:0031175//neuron projection development;GO:0002209//behavioral defense response;GO:0051899//membrane depolarization;GO:0014070//response to organic cyclic compound;GO:0008037//cell recognition;GO:0033273//response to vitamin;GO:0042493//response to drug;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0035295//tube development;GO:0009719;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0007416//synapse assembly;GO:0022904//respiratory electron transport chain;GO:0044708//single-organism behavior;GO:0033555//multicellular organismal response to stress;GO:0043066//negative regulation of apoptotic process;GO:0006835//dicarboxylic acid transport;GO:0043583//ear development;GO:0014706//striated muscle tissue development;GO:0007405//neuroblast proliferation;GO:0031175//neuron projection development;GO:0002209//behavioral defense response;GO:0051899//membrane depolarization;GO:0014070//response to organic cyclic compound;GO:0008037//cell recognition;GO:0033273//response to vitamin;GO:0042493//response to drug;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0035295//tube development;GO:0009719;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0007416//synapse assembly;GO:0022904//respiratory electron transport chain;GO:0044708//single-organism behavior;GO:0033555//multicellular organismal response to stress;GO:0043066//negative regulation of apoptotic process;GO:0006835//dicarboxylic acid transport;GO:0043583//ear development;GO:0014706//striated muscle tissue development;GO:0007405//neuroblast proliferation;GO:0031175//neuron projection development;GO:0002209//behavioral defense response;GO:0051899//membrane depolarization;GO:0014070//response to organic cyclic compound;GO:0008037//cell recognition;GO:0033273//response to vitamin;GO:0042493//response to drug;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0035295//tube development;GO:0009719;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0007416//synapse assembly;GO:0022904//respiratory electron transport chain;GO:0044708//single-organism behavior;GO:0033555//multicellular organismal response to stress;GO:0043066//negative regulation of apoptotic process;GO:0006835//dicarboxylic acid transport;GO:0043583//ear development;GO:0014706//striated muscle tissue development;GO:0007405//neuroblast proliferation;GO:0031175//neuron projection development;GO:0002209//behavioral defense response;GO:0051899//membrane depolarization;GO:0014070//response to organic cyclic compound;GO:0008037//cell recognition;GO:0033273//response to vitamin;GO:0042493//response to drug;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0035295//tube development;GO:0009719;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0007416//synapse assembly;GO:0022904//respiratory electron transport chain;GO:0044708//single-organism behavior;GO:0033555//multicellular organismal response to stress;GO:0043066//negative regulation of apoptotic process;GO:0006835//dicarboxylic acid transport;GO:0043583//ear development;GO:0014706//striated muscle tissue development;GO:0007405//neuroblast proliferation;GO:0031175//neuron projection development;GO:0002209//behavioral defense response;GO:0051899//membrane depolarization;GO:0014070//response to organic cyclic compound;GO:0008037//cell recognition;GO:0033273//response to vitamin;GO:0042493//response to drug;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0035295//tube development;GO:0009719;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0007416//synapse assembly;GO:0022904//respiratory electron transport chain;GO:0044708//single-organism behavior;GO:0033555//multicellular organismal response to stress;GO:0043066//negative regulation of apoptotic process;GO:0006835//dicarboxylic acid transport;GO:0043583//ear development;GO:0014706//striated muscle tissue development;GO:0007405//neuroblast proliferation;GO:0031175//neuron projection development;GO:0002209//behavioral defense response;GO:0051899//membrane depolarization;GO:0014070//response to organic cyclic compound;GO:0008037//cell recognition;GO:0033273//response to vitamin;GO:0042493//response to drug;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0035295//tube development;GO:0009719;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0007416//synapse assembly;GO:0022904//respiratory electron transport chain;GO:0044708//single-organism behavior;GO:0033555//multicellular organismal response to stress;GO:0043066//negative regulation of apoptotic process;GO:0006835//dicarboxylic acid transport;GO:0043583//ear development;GO:0014706//striated muscle tissue development;GO:0007405//neuroblast proliferation;GO:0031175//neuron projection development;GO:0051899//membrane depolarization;GO:0014070//response to organic cyclic compound;GO:0008037//cell recognition;GO:0033273//response to vitamin;GO:0042493//response to drug;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0035295//tube development;GO:0009719;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0007416//synapse assembly;GO:0022904//respiratory electron transport chain;GO:0044708//single-organism behavior;GO:0033555//multicellular organismal response to stress;GO:0043066//negative regulation of apoptotic process;GO:0006835//dicarboxylic acid transport;GO:0043583//ear development;GO:0014706//striated muscle tissue development;GO:0007405//neuroblast proliferation;GO:0031175//neuron projection development;GO:0002209//behavioral defense response;GO:0051899//membrane depolarization;GO:0014070//response to organic cyclic compound;GO:0008037//cell recognition;GO:0033273//response to vitamin;GO:0042493//response to drug;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0035295//tube development;GO:0009719;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0007416//synapse assembly;GO:0022904//respiratory electron transport chain;GO:0044708//single-organism behavior;GO:0033555//multicellular organismal response to stress;GO:0043066//negative regulation of apoptotic process;GO:0006835//dicarboxylic acid transport;GO:0043583//ear development;GO:0014706//striated muscle tissue development;GO:0007405//neuroblast proliferation;GO:0031175//neuron projection development;GO:0002209//behavioral defense response;GO:0051899//membrane depolarization;GO:0014070//response to organic cyclic compound;GO:0008037//cell recognition;GO:0033273//response to vitamin;GO:0042493//response to drug;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0035295//tube development;GO:0009719;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0007416//synapse assembly;GO:0022904//respiratory electron transport chain;GO:0044708//single-organism behavior;GO:0033555//multicellular organismal response to stress;GO:0043066//negative regulation of apoptotic process;GO:0006835//dicarboxylic acid transport;GO:0043583//ear development;GO:0014706//striated muscle tissue development;GO:0007405//neuroblast proliferation;GO:0031175//neuron projection development;GO:0002209//behavioral defense response;GO:0051899//membrane depolarization;GO:0014070//response to organic cyclic compound;GO:0008037//cell recognition;GO:0033273//response to vitamin;GO:0042493//response to drug;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0035295//tube development;GO:0009719;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0007416//synapse assembly;GO:0022904//respiratory electron transport chain;GO:0044708//single-organism behavior;GO:0033555//multicellular organismal response to stress;GO:0043066//negative regulation of apoptotic process;GO:0006835//dicarboxylic acid transport;GO:0043583//ear development;GO:0014706//striated muscle tissue development;GO:0007405//neuroblast proliferation;GO:0031175//neuron projection development;GO:0051899//membrane depolarization;GO:0014070//response to organic cyclic compound;GO:0008037//cell recognition;GO:0033273//response to vitamin;GO:0042493//response to drug;GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0035295//tube development;GO:0009719;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0007416//synapse assembly;GO:0022904//respiratory electron transport chain;GO:0044708//single-organism behavior gi|114326463|ref|NP_031566.4|/3.36679e-137/brain-derived neurotrophic factor isoform 1 precursor [Mus musculus] 216846 3950 1.23 1.063333333 -0.210064392 Down 0.183807214 Cntrob "centrobin, centrosomal BRCA2 interacting protein" K16468|1|0.0|1638|mmu:216846|centrobin GO:0005813//centrosome GO:0005515//protein binding GO:0007098//centrosome cycle gi|145976948|ref|NP_766148.2|/0/centrobin [Mus musculus] 226646 1623 732.8233333 757.19 0.047189918 Up 0.183797811 Ndufs2 NADH dehydrogenase (ubiquinone) Fe-S protein 2 K03935|1|0.0|953|mmu:226646|NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3] - - - - 68202 546.98 569.17 548.1133333 -0.054385392 Down 0.18367558 Ndufa5 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5" K03949|1|1e-50|201|rno:25488|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5 GO:0005746//mitochondrial respiratory chain GO:0016491//oxidoreductase activity GO:0051234//establishment of localization;GO:0022900//electron transport chain gi|901694076|ref|NP_001297997.1|/8.69193e-31/NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform 2 [Mus musculus] 107321 1673 0.623333333 0.496666667 -0.327725939 Down 0.183656775 Lpxn leupaxin K05760|1|6e-118|427|gga:395832|paxillin GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0005924//cell-substrate adherens junction "GO:0046914//transition metal ion binding;GO:0000989//transcription factor activity, transcription factor binding" "GO:0010556;GO:0050853//B cell receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0030155//regulation of cell adhesion;GO:0065003" "gi|148709540|gb|EDL41486.1|/0/leupaxin, isoform CRA_a, partial [Mus musculus]" 19288 1924 0.633333333 0.503333333 -0.331450869 Down 0.183656775 Ptx3 pentraxin related gene K01115|1|3e-43|179|lcm:102353212|phospholipase D1/2 [EC:3.1.4.4];K01672|2|6e-19|98.6|dre:100006448|carbonic anhydrase [EC:4.2.1.1] - GO:0030247//polysaccharide binding GO:0006909//phagocytosis;GO:0006952//defense response;GO:0006809//nitric oxide biosynthetic process;GO:0002252;GO:0009620//response to fungus gi|113930726|ref|NP_033013.3|/0/pentraxin-related protein PTX3 precursor [Mus musculus] 110826 920 575.7833333 594.9633333 0.047274731 Up 0.183628568 Etfb "electron transferring flavoprotein, beta polypeptide" K03521|1|1e-129|464|mmu:110826|electron transfer flavoprotein beta subunit GO:0005759//mitochondrial matrix;GO:0005759//mitochondrial matrix - GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy gi|38142460|ref|NP_080971.2|/8.86216e-129/electron transfer flavoprotein subunit beta [Mus musculus] 68263 1485 542.9733333 524.0266667 -0.051241116 Down 0.183619166 Pdhb pyruvate dehydrogenase (lipoamide) beta K00162|1|0.0|716|mmu:68263|pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1] GO:0043234//protein complex;GO:0044429 GO:0004738//pyruvate dehydrogenase activity GO:0019318//hexose metabolic process;GO:0006086//acetyl-CoA biosynthetic process from pyruvate;GO:0009060//aerobic respiration "gi|18152793|ref|NP_077183.1|/0/pyruvate dehydrogenase E1 component subunit beta, mitochondrial precursor [Mus musculus]" 108672 5517 0.14 0.06 -1.222392421 Down 0.183572154 Zdhhc15 "zinc finger, DHHC domain containing 15" K20028|1|0.0|692|ocu:100354388|palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225] GO:0031224//intrinsic component of membrane "GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0046914//transition metal ion binding" GO:0006497//protein lipidation;GO:0008104//protein localization;GO:0016050//vesicle organization gi|655886694|ref|XP_008247070.1|/0/PREDICTED: LOW QUALITY PROTEIN: palmitoyltransferase ZDHHC15 [Oryctolagus cuniculus] 434008 3092 0.14 0.06 -1.222392421 Down 0.183572154 Tmem178b transmembrane protein 178B - - - - gi|51921359|ref|NP_001004182.1|/4.62314e-80/transmembrane protein 178B [Mus musculus] 56792 1111 0.176666667 0.28 0.664396968 Up 0.183562752 Stap1 signal transducing adaptor family member 1 - GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen "GO:0008289//lipid binding;GO:0030674//protein binding, bridging;GO:0008289//lipid binding;GO:0030674//protein binding, bridging" GO:0030097//hemopoiesis;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0030097//hemopoiesis;GO:0007167//enzyme linked receptor protein signaling pathway gi|890765057|ref|NP_001297568.1|/5.97817e-136/signal-transducing adaptor protein 1 isoform 2 [Mus musculus] 109242 5616 0.273333333 0.173333333 -0.657112286 Down 0.183562752 Kif24 kinesin family member 24 K10393|1|0.0|2516|mmu:109242|kinesin family member 2/24 GO:0005813//centrosome GO:0032550;GO:0003774//motor activity GO:0010927;GO:0031109//microtubule polymerization or depolymerization;GO:0006928//movement of cell or subcellular component gi|154689823|ref|NP_077203.2|/0/kinesin-like protein KIF24 [Mus musculus] 234267 2980 0.396666667 0.52 0.390584456 Up 0.18347813 Gpm6a glycoprotein m6a K17271|1|3e-49|199|ecb:100053823|myelin proteolipid protein GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0044297//cell body;GO:0030426//growth cone;GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0044297//cell body;GO:0030426//growth cone;GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0044297//cell body;GO:0030426//growth cone GO:0005488//binding;GO:0005261//cation channel activity;GO:0005488//binding;GO:0005261//cation channel activity;GO:0005488//binding;GO:0005261//cation channel activity GO:0016477//cell migration;GO:0031346//positive regulation of cell projection organization;GO:0031175//neuron projection development;GO:0006816//calcium ion transport;GO:0016477//cell migration;GO:0031346//positive regulation of cell projection organization;GO:0031175//neuron projection development;GO:0006816//calcium ion transport;GO:0016477//cell migration;GO:0031346//positive regulation of cell projection organization;GO:0031175//neuron projection development;GO:0006816//calcium ion transport gi|390460231|ref|XP_002745248.2|/1.59874e-154/PREDICTED: neuronal membrane glycoprotein M6-a isoform X1 [Callithrix jacchus] 22333 2036 511.7833333 528.8433333 0.04730723 Up 0.183431118 Vdac1 voltage-dependent anion channel 1 K05862|1|4e-162|574|rno:83529|voltage-dependent anion channel protein 1 - - - - 74081 13307 1.613333333 1.426666667 -0.177396251 Down 0.183412313 Cep350 centrosomal protein 350 K16768|1|0.0|5256|mmu:74081|centrosomal protein CEP350 - - - - 66700 2592 22.83 23.84 0.062453376 Up 0.183412313 Chmp3 charged multivesicular body protein 3 K12193|1|4e-103|378|mcc:697894|charged multivesicular body protein 3 GO:0005770//late endosome GO:0043168//anion binding GO:0007041//lysosomal transport;GO:0045184//establishment of protein localization;GO:0032535//regulation of cellular component size gi|676278626|gb|KFO32638.1|/9.24437e-103/Charged multivesicular body protein 3 [Fukomys damarensis] 17300 3990 1.42 1.61 0.181169759 Up 0.183412313 Foxc1 forkhead box C1 K09396|1|2e-176|622|mmu:17300|forkhead box protein C - - - - 20965 3288.96 1.57 1.383333333 -0.182615723 Down 0.183412313 Syn2 synapsin II K19941|1|0.0|759|mmu:20965|synapsin GO:0008021//synaptic vesicle;GO:0008021//synaptic vesicle GO:0032550;GO:0005515//protein binding;GO:0032550;GO:0005515//protein binding GO:0007269//neurotransmitter secretion;GO:0007269//neurotransmitter secretion gi|8567410|ref|NP_038709.1|/0/synapsin-2 isoform IIb [Mus musculus] 353342 4745 24.59 25.6 0.058072075 Up 0.183412313 Peg13 paternally expressed 13 - - - - - 102278 2421 0.383333333 0.273333333 -0.487938046 Down 0.183402911 Cpne7 copine VII K06491|1|4e-08|63.2|cin:100183448|neural cell adhesion molecule - - GO:0044238//primary metabolic process;GO:0051234//establishment of localization gi|25470894|ref|NP_733785.1|/0/copine-7 [Mus musculus] 268903 4529 0.396666667 0.283333333 -0.485426827 Down 0.183402911 Nrip1 nuclear receptor interacting protein 1 K17965|1|0.0|2204|mmu:268903|nuclear receptor-interacting protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0042974//retinoic acid receptor binding;GO:0035258//steroid hormone receptor binding;GO:0019899//enzyme binding GO:0001542//ovulation from ovarian follicle;GO:0006366//transcription from RNA polymerase II promoter;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0010876//lipid localization gi|27734110|ref|NP_775616.1|/0/nuclear receptor-interacting protein 1 [Mus musculus] 17295 6652 0.266666667 0.373333333 0.485426827 Up 0.183402911 Met met proto-oncogene K05099|1|0.0|2642|mmu:17295|proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] GO:0031224//intrinsic component of membrane;GO:0016323//basolateral plasma membrane;GO:0031514//motile cilium;GO:0044327//dendritic spine head;GO:0044297//cell body;GO:0044421;GO:0097060//synaptic membrane GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032550;GO:0046983//protein dimerization activity;GO:0019899//enzyme binding GO:0046685//response to arsenic-containing substance;GO:0070741//response to interleukin-6;GO:0010035//response to inorganic substance;GO:0008406//gonad development;GO:0007268//chemical synaptic transmission;GO:0021782//glial cell development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0051899//membrane depolarization;GO:0043069//negative regulation of programmed cell death;GO:0035914//skeletal muscle cell differentiation;GO:0001678//cellular glucose homeostasis;GO:0031346//positive regulation of cell projection organization;GO:0032870//cellular response to hormone stimulus;GO:0001933//negative regulation of protein phosphorylation;GO:0016477//cell migration;GO:0007589//body fluid secretion;GO:0001934//positive regulation of protein phosphorylation;GO:0010975//regulation of neuron projection development;GO:0007568//aging;GO:0070848//response to growth factor;GO:0006260//DNA replication;GO:0007417//central nervous system development;GO:0010827//regulation of glucose transport;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006950//response to stress;GO:0007067//mitotic nuclear division;GO:0060562//epithelial tube morphogenesis;GO:0060638//mesenchymal-epithelial cell signaling gi|146198696|ref|NP_032617.2|/0/hepatocyte growth factor receptor precursor [Mus musculus] 69108 542 0.1 0.19 0.925999419 Up 0.183384106 1810012K16Rik RIKEN cDNA 1810012K16 gene - - - - - 14527 1929 0.18 0.093333333 -0.94753258 Down 0.183384106 Gcgr glucagon receptor K04583|1|0.0|932|mmu:14527|glucagon receptor GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0042277//peptide binding;GO:0004930//G-protein coupled receptor activity GO:0016192//vesicle-mediated transport;GO:0033762//response to glucagon;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway gi|160298176|ref|NP_032127.2|/0/glucagon receptor precursor [Mus musculus] 624860 1356 0.183333333 0.093333333 -0.974004791 Down 0.183384106 Gm12253 predicted gene 12253 K10591|1|4e-07|58.5|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26];K06552|2|2e-06|56.2|ecb:100069985|CD177 antigen - - GO:0048771//tissue remodeling gi|113865925|ref|NP_001039007.1|/1.4211e-132/uncharacterized protein LOC624860 precursor [Mus musculus] 75497 2549 0.1 0.193333333 0.9510904 Up 0.183384106 Fabp12 fatty acid binding protein 12 "K08753|1|2e-42|177|cmy:102944355|fatty acid-binding protein 4, adipocyte" - GO:0005488//binding GO:0051234//establishment of localization gi|58037415|ref|NP_083586.1|/1.9046e-68/fatty acid-binding protein 12 [Mus musculus] 14407 1673 0.093333333 0.183333333 0.974004791 Up 0.183384106 Gabrg3 "gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3" K05186|1|0.0|889|mmu:14407|gmma-aminobutyric acid receptor subunit gamma GO:0097060//synaptic membrane;GO:0034702//ion channel complex GO:0005253//anion channel activity;GO:0016917//GABA receptor activity;GO:0015276//ligand-gated ion channel activity GO:0007267//cell-cell signaling;GO:0042221//response to chemical;GO:0015698//inorganic anion transport;GO:0007186//G-protein coupled receptor signaling pathway gi|117168291|ref|NP_032100.2|/0/gamma-aminobutyric acid receptor subunit gamma-3 precursor [Mus musculus] 626877 1699 0.1 0.193333333 0.9510904 Up 0.183384106 Gm14405 predicted gene 14405 K09228|1|1e-173|587|mmu:100043915|KRAB domain-containing zinc finger protein - - - gi|294774589|ref|NP_001171039.1|/0/KRAB box and zinc finger C2H2 type domain containing protein-like [Mus musculus] 54683 688 509.52 493.86 -0.045036654 Down 0.183337094 Prdx5 peroxiredoxin 5 "K11187|1|2e-108|393|mmu:54683|peroxiredoxin 5, atypical 2-Cys peroxiredoxin [EC:1.11.1.15]" GO:0031982//vesicle;GO:0005829//cytosol;GO:0044439 GO:0005515//protein binding;GO:0051920//peroxiredoxin activity;GO:0044212//transcription regulatory region DNA binding;GO:0016209//antioxidant activity;GO:0004869//cysteine-type endopeptidase inhibitor activity GO:0006383//transcription from RNA polymerase III promoter;GO:0043086//negative regulation of catalytic activity;GO:0042981//regulation of apoptotic process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0042743//hydrogen peroxide metabolic process;GO:0000302//response to reactive oxygen species;GO:0055114//oxidation-reduction process "gi|6755114|ref|NP_036151.1|/1.41397e-107/peroxiredoxin-5, mitochondrial precursor [Mus musculus]" 67441 1065 3.786666667 3.5 -0.113573507 Down 0.183205461 Isoc2b isochorismatase domain containing 2b K04432|1|1e-07|59.7|tsp:Tsp_02206|mitogen-activated protein kinase kinase 3 [EC:2.7.12.2] - - - - 57443 2821.86 24.77 23.77333333 -0.059249666 Down 0.183158449 Fbxo3 F-box protein 3 K10290|1|0.0|833|ocu:100348804|F-box protein 3 - GO:0005488//binding;GO:0019787//ubiquitin-like protein transferase activity GO:0032446//protein modification by small protein conjugation gi|46877055|ref|NP_997598.1|/0/F-box only protein 3 isoform 1 [Mus musculus] 100124433 77 24.99 23.99333333 -0.0587173 Down 0.183158449 Mir208b microRNA 208b - - - - - 66053 1954.04 25.53 26.53333333 0.055612392 Up 0.183158449 Ppil2 peptidylprolyl isomerase (cyclophilin)-like 2 K10598|1|0.0|1014|mmu:66053|peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0016859//cis-trans isomerase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0016859//cis-trans isomerase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0016859//cis-trans isomerase activity;GO:0004842//ubiquitin-protein transferase activity GO:0016567//protein ubiquitination;GO:0016567//protein ubiquitination;GO:0016567//protein ubiquitination gi|26349387|dbj|BAC38333.1|/0/unnamed protein product [Mus musculus] 212073 5299.42 0.766666667 0.63 -0.283247627 Down 0.183139644 Syne3 "spectrin repeat containing, nuclear envelope family member 3" K19326|1|6e-61|239|ptg:102970011|nesprin-1 GO:0031965//nuclear membrane;GO:0034992//microtubule organizing center attachment site;GO:0031224//intrinsic component of membrane;GO:0031965//nuclear membrane;GO:0034992//microtubule organizing center attachment site;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding GO:0022604//regulation of cell morphogenesis;GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis;GO:0007010//cytoskeleton organization gi|111607453|ref|NP_001036164.1|/0/nesprin-3 isoform alpha [Mus musculus] 11988 7720 0.666666667 0.806666667 0.275007047 Up 0.183139644 Slc7a2 "solute carrier family 7 (cationic amino acid transporter, y+ system), member 2" "K13864|1|0.0|1172|mmu:11988|solute carrier family 7 (cationic amino acid transporter), member 2" GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424 GO:0005287;GO:0008324//cation transmembrane transporter activity;GO:0005287;GO:0008324//cation transmembrane transporter activity GO:0002694;GO:0002532//production of molecular mediator involved in inflammatory response;GO:0044271//cellular nitrogen compound biosynthetic process;GO:0002274;GO:0006812//cation transport;GO:0006865//amino acid transport;GO:0002694;GO:0002532//production of molecular mediator involved in inflammatory response;GO:0044271//cellular nitrogen compound biosynthetic process;GO:0002274;GO:0006812//cation transport;GO:0006865//amino acid transport gi|568954482|ref|XP_006509314.1|/0/PREDICTED: cationic amino acid transporter 2 isoform X3 [Mus musculus] 11596 1333 0.806666667 0.663333333 -0.282238617 Down 0.183139644 Ager advanced glycosylation end product-specific receptor K19722|1|0.0|673|mmu:11596|receptor for advanced glycosylation end products GO:0043005//neuron projection;GO:0044297//cell body;GO:0016323//basolateral plasma membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0043005//neuron projection;GO:0044297//cell body;GO:0016323//basolateral plasma membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0043005//neuron projection;GO:0044297//cell body;GO:0016323//basolateral plasma membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0043005//neuron projection;GO:0044297//cell body;GO:0016323//basolateral plasma membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0043005//neuron projection;GO:0044297//cell body;GO:0016323//basolateral plasma membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0043005//neuron projection;GO:0044297//cell body;GO:0016323//basolateral plasma membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0043005//neuron projection;GO:0044297//cell body;GO:0016323//basolateral plasma membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044421 GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0005515//protein binding;GO:0038023//signaling receptor activity GO:0055065//metal ion homeostasis;GO:0007417//central nervous system development;GO:0050927//positive regulation of positive chemotaxis;GO:0010761//fibroblast migration;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0030030//cell projection organization;GO:0030323//respiratory tube development;GO:0006954//inflammatory response;GO:0055065//metal ion homeostasis;GO:0007417//central nervous system development;GO:0050927//positive regulation of positive chemotaxis;GO:0010761//fibroblast migration;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0030030//cell projection organization;GO:0030323//respiratory tube development;GO:0006954//inflammatory response;GO:0055065//metal ion homeostasis;GO:0007417//central nervous system development;GO:0050927//positive regulation of positive chemotaxis;GO:0010761//fibroblast migration;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0030030//cell projection organization;GO:0030323//respiratory tube development;GO:0006954//inflammatory response;GO:0055065//metal ion homeostasis;GO:0007417//central nervous system development;GO:0050927//positive regulation of positive chemotaxis;GO:0010761//fibroblast migration;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0030030//cell projection organization;GO:0030323//respiratory tube development;GO:0006954//inflammatory response;GO:0055065//metal ion homeostasis;GO:0050927//positive regulation of positive chemotaxis;GO:0010761//fibroblast migration;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0030030//cell projection organization;GO:0006954//inflammatory response;GO:0055065//metal ion homeostasis;GO:0007417//central nervous system development;GO:0050927//positive regulation of positive chemotaxis;GO:0010761//fibroblast migration;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0030030//cell projection organization;GO:0030323//respiratory tube development;GO:0006954//inflammatory response;GO:0055065//metal ion homeostasis;GO:0007417//central nervous system development;GO:0050927//positive regulation of positive chemotaxis;GO:0010761//fibroblast migration;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0030030//cell projection organization;GO:0030323//respiratory tube development;GO:0006954//inflammatory response gi|406855406|ref|NP_001258352.1|/0/advanced glycosylation end product-specific receptor isoform c precursor [Mus musculus] 16618 877 0.766666667 0.63 -0.283247627 Down 0.183139644 Klk1b26 kallikrein 1-related petidase b26 K01325|1|3e-156|553|mmu:16618|tissue kallikrein [EC:3.4.21.35];K09462|2|1e-149|530|mmu:13647|glandular kallikrein 13 [EC:3.4.21.119];K01339|4|4e-131|469|mmu:16615|g-renin [EC:3.4.21.54] - - - - 64209 1871 376.3333333 389.57 0.049871502 Up 0.183102035 Herpud1 "homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1" K14027|1|0.0|679|mmu:64209|homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane - GO:0043393//regulation of protein binding;GO:0006915//apoptotic process;GO:0019941//modification-dependent protein catabolic process;GO:0006875//cellular metal ion homeostasis;GO:0016567//protein ubiquitination;GO:0035966//response to topologically incorrect protein;GO:0006984//ER-nucleus signaling pathway gi|50510333|dbj|BAD32152.1|/0/mKIAA0025 protein [Mus musculus] 18718 3471 4.5 4.82 0.099108145 Up 0.183092632 Pip4k2a "phosphatidylinositol-5-phosphate 4-kinase, type II, alpha" K00920|1|0.0|731|mmu:18718|1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0032550;GO:0016307//phosphatidylinositol phosphate kinase activity GO:0046474//glycerophospholipid biosynthetic process;GO:0030219//megakaryocyte differentiation gi|125490368|ref|NP_032871.3|/0/phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [Mus musculus] 223828 3788.76 4.36 4.676666667 0.101152468 Up 0.183092632 Pphln1 periphilin 1 - - - - - 67235 1992 4.34 4.663333333 0.103666514 Up 0.183092632 Zkscan14 zinc finger with KRAB and SCAN domains 14 K09229|1|0.0|1020|mmu:67235|KRAB and SCAN domains-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0044764;GO:0006351//transcription, DNA-templated" gi|114158685|ref|NP_075811.2|/0/zinc finger protein 394 [Mus musculus] 239273 5583.9 4.423333333 4.74 0.099753094 Up 0.183092632 Abcc4 "ATP-binding cassette, sub-family C (CFTR/MRP), member 4" "K05673|1|0.0|2261|mmu:239273|ATP-binding cassette, subfamily C (CFTR/MRP), member 4" GO:0031224//intrinsic component of membrane;GO:0044459;GO:0030667//secretory granule membrane;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0030667//secretory granule membrane;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0030667//secretory granule membrane GO:0032550;GO:0015405;GO:0032550;GO:0015405;GO:0032550;GO:0015405 GO:0009719;GO:0008284//positive regulation of cell proliferation;GO:0010033//response to organic substance;GO:0009719;GO:0008284//positive regulation of cell proliferation;GO:0010033//response to organic substance;GO:0009719;GO:0008284//positive regulation of cell proliferation;GO:0010033//response to organic substance gi|255683328|ref|NP_001157148.1|/0/multidrug resistance-associated protein 4 isoform 3 [Mus musculus] 13017 3047 5.05 4.726666667 -0.095460261 Down 0.183092632 Ctbp2 C-terminal binding protein 2 K04496|1|0.0|1873|rno:81717|C-terminal binding protein GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0003712//transcription cofactor activity;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding;GO:0003712//transcription cofactor activity;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding" "GO:0044710;GO:0019058//viral life cycle;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0045444//fat cell differentiation;GO:0006351//transcription, DNA-templated;GO:0045444//fat cell differentiation" gi|282721029|ref|NP_001164215.1|/0/C-terminal-binding protein 2 isoform 1 [Mus musculus] 378954 1279 1.003333333 1.166666667 0.217591435 Up 0.183073828 3000002C10Rik glyceraldehyde-3-phosphate dehydrogenase pseudogene K00134|1|5e-158|409|ngi:103737766|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0000166//nucleotide binding;GO:0015631//tubulin binding" GO:0006007//glucose catabolic process;GO:0006412//translation;GO:0012501//programmed cell death;GO:0070997//neuron death;GO:0044710;GO:0007010//cytoskeleton organization;GO:0031647//regulation of protein stability;GO:0018119//peptidyl-cysteine S-nitrosylation gi|55153885|gb|AAH85315.1|/1.55321e-160/Glyceraldehyde-3-phosphate dehydrogenase [Mus musculus] 544971 9921 1.086666667 0.93 -0.224606842 Down 0.183073828 Bdp1 "B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB" K15198|1|0.0|4487|mmu:544971|transcription factor TFIIIB component B'' - - - gi|145587077|ref|NP_001074530.1|/0/transcription factor TFIIIB component B'' homolog [Mus musculus] 73103 520 1.41 1.233333333 -0.193132393 Down 0.183055023 3110009E18Rik RIKEN cDNA 3110009E18 gene - - - - "gi|148707853|gb|EDL39800.1|/1.95458e-62/RIKEN cDNA 3110009E18, isoform CRA_b, partial [Mus musculus]" 22698 3890 1.446666667 1.27 -0.187904045 Down 0.183055023 Zfp39 zinc finger protein 39 K09228|1|0.0|1520|mmu:22698|KRAB domain-containing zinc finger protein - - - gi|83816962|ref|NP_035888.2|/0/zinc finger protein 39 [Mus musculus] 71186 1229 0.526666667 0.656666667 0.318271071 Up 0.183055023 4933417D19Rik RIKEN cDNA 4933417D19 gene - - - - "gi|148679777|gb|EDL11724.1|/4.7993e-52/mCG145942, partial [Mus musculus]" 69270 951.5 1.326666667 1.51 0.18674262 Up 0.183055023 Gins1 GINS complex subunit 1 (Psf1 homolog) K10732|1|4e-111|403|mmu:69270|GINS complex subunit 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding GO:0006259//DNA metabolic process;GO:0001832//blastocyst growth;GO:0006259//DNA metabolic process;GO:0001832//blastocyst growth gi|254553280|ref|NP_001156948.1|/8.80734e-91/DNA replication complex GINS protein PSF1 isoform 2 [Mus musculus] 235469 4339 1.25 1.426666667 0.190720201 Up 0.183055023 Zfp280d zinc finger protein 280D K08776|1|3e-21|107|cmk:103185706|puromycin-sensitive aminopeptidase [EC:3.4.11.-];K09228|2|3e-15|87.8|mde:101887374|KRAB domain-containing zinc finger protein - - - - 208727 8100 3.326666667 3.063333333 -0.118974954 Down 0.183026816 Hdac4 histone deacetylase 4 K11406|1|0.0|1793|mmu:208727|histone deacetylase 4/5 [EC:3.5.1.98] - - - - 236511 7255 3.096666667 2.84 -0.124825166 Down 0.183026816 Ago1 argonaute RISC catalytic subunit 1 K11593|1|0.0|1756|pale:102879797|eukaryotic translation initiation factor 2C - - - - 54353 1656 2.856666667 3.113333333 0.124127346 Up 0.183026816 Skap2 src family associated phosphoprotein 2 K17699|1|1e-84|316|lcm:102350764|src kinase associated phosphoprotein 1 GO:0016020//membrane;GO:0044424 GO:0008289//lipid binding GO:0046649//lymphocyte activation;GO:0008283//cell proliferation gi|9055324|ref|NP_061243.1|/0/src kinase-associated phosphoprotein 2 [Mus musculus] 208228 2687 2.993333333 3.253333333 0.120165703 Up 0.183026816 Mob3a MOB kinase activator 3A K06685|1|7e-79|298|cel:CELE_T12B3.4|MOB kinase activator 1 GO:0044464 "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0043169//cation binding" GO:0006796//phosphate-containing compound metabolic process gi|124249075|ref|NP_766045.2|/1.0548e-125/MOB kinase activator 3A [Mus musculus] 224111 10318 2.693333333 2.453333333 -0.134649527 Down 0.183017413 Ubxn7 UBX domain protein 7 K18726|1|2e-06|59.7|tca:664346|FAS-associated factor 2 GO:0005789//endoplasmic reticulum membrane GO:0044389//ubiquitin-like protein ligase binding;GO:0032182//ubiquitin-like protein binding - gi|268839673|ref|NP_808301.3|/0/UBX domain-containing protein 7 [Mus musculus] 329575 4394 2.586666667 2.826666667 0.128007612 Up 0.183017413 Gm14325 predicted gene 14325 K09228|1|0.0|1055|mmu:665211|KRAB domain-containing zinc finger protein - - - "gi|326633249|ref|NP_001020020.2|/0/novel KRAB box and zinc finger, C2H2 type domain containing protein [Mus musculus]" 75425 3798 12.39666667 11.80333333 -0.070757904 Down 0.183008011 Tti1 TELO2 interacting protein 1 K20403|1|0.0|1909|mmu:75425|TELO2-interacting protein 1 - - - - 218215 4540 12.17 12.76 0.068299161 Up 0.183008011 Rnf144b ring finger protein 144B K11975|1|2e-178|629|mmu:218215|E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.27] GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane;GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0016567//protein ubiquitination;GO:0012501//programmed cell death;GO:0016567//protein ubiquitination;GO:0012501//programmed cell death gi|282165743|ref|NP_666154.3|/2.14477e-177/E3 ubiquitin-protein ligase RNF144B [Mus musculus] 22334 1662 301.06 312.4733333 0.053682036 Up 0.182876377 Vdac2 voltage-dependent anion channel 2 K15040|1|2e-152|541|cge:100761812|voltage-dependent anion channel protein 2 GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane;GO:0019866//organelle inner membrane;GO:0005759//mitochondrial matrix GO:0022829//wide pore channel activity;GO:0005244//voltage-gated ion channel activity;GO:0036094//small molecule binding GO:0097193//intrinsic apoptotic signaling pathway;GO:0031333//negative regulation of protein complex assembly;GO:0006820//anion transport "gi|190200|gb|AAA60144.1|/6.04307e-164/porin, partial [Homo sapiens]" 109697 1594 0.066666667 0.15 1.169925001 Up 0.182866975 Cpa1 "carboxypeptidase A1, pancreatic" K08779|1|0.0|825|mmu:109697|carboxypeptidase A1 [EC:3.4.17.1] GO:0044421 GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding GO:0006508//proteolysis gi|54312076|ref|NP_079626.2|/0/carboxypeptidase A1 preproprotein [Mus musculus] 71920 1704 0.06 0.136666667 1.187627003 Up 0.182866975 Epgn epithelial mitogen "K13403|1|1e-43|180|apla:101797763|methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]" GO:0016021//integral component of membrane GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0070851//growth factor receptor binding GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0008284//positive regulation of cell proliferation;GO:0007067//mitotic nuclear division;GO:0043405//regulation of MAP kinase activity;GO:0048646//anatomical structure formation involved in morphogenesis gi|16716373|ref|NP_444317.1|/3.34638e-84/epigen precursor [Mus musculus] 22272 1521.43 324.3766667 335.6733333 0.049387884 Up 0.182857573 Uqcrq "ubiquinol-cytochrome c reductase, complex III subunit VII" K00418|1|9e-41|170|mmu:22272|ubiquinol-cytochrome c reductase subunit 8 - - - - 52123 3829 5.803333333 6.17 0.088388692 Up 0.182819963 Agpat5 "1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)" K19007|1|0.0|743|mmu:52123|lysophosphatidiate acyltransferase [EC:2.3.1.51] GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane;GO:0012505//endomembrane system GO:0016411//acylglycerol O-acyltransferase activity GO:0046341//CDP-diacylglycerol metabolic process;GO:0006641//triglyceride metabolic process;GO:0046473//phosphatidic acid metabolic process gi|27229077|ref|NP_081068.1|/0/1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [Mus musculus] 20492 1921 5.446666667 5.816666667 0.094819053 Up 0.182819963 Slbp stem-loop binding protein K18710|1|6e-114|414|mmu:20492|histone RNA hairpin-binding protein GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0036002//pre-mRNA binding;GO:0036002//pre-mRNA binding;GO:0036002//pre-mRNA binding GO:0006396//RNA processing;GO:0010564//regulation of cell cycle process;GO:0050658//RNA transport;GO:0006261//DNA-dependent DNA replication;GO:0008334//histone mRNA metabolic process;GO:0022402//cell cycle process;GO:0008334//histone mRNA metabolic process;GO:0006396//RNA processing;GO:0010564//regulation of cell cycle process;GO:0050658//RNA transport;GO:0006261//DNA-dependent DNA replication;GO:0008334//histone mRNA metabolic process gi|576067823|ref|NP_001276653.1|/1.2806e-116/histone RNA hairpin-binding protein isoform 2 [Mus musculus] 69641 2427 5.836666667 5.47 -0.093603845 Down 0.182819963 Wdr20 WD repeat domain 20 K06100|1|9e-105|384|aam:106490508|symplekin;K12602|5|4e-11|72.8|api:100164117|WD repeat-containing protein 61 - - - - 214230 4030.96 6.46 6.09 -0.085091937 Down 0.182819963 Pak6 p21 protein (Cdc42/Rac)-activated kinase 6 K05735|1|0.0|1364|mmu:214230|p21-activated kinase 6 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|224994207|ref|NP_001028426.2|/0/serine/threonine-protein kinase PAK 6 [Mus musculus] 73205 3198 5.98 6.35 0.086611107 Up 0.182819963 3110043O21Rik RIKEN cDNA 3110043O21 gene - - - - - 56494 3078 22.59333333 21.61333333 -0.063975546 Down 0.182772951 Gosr2 golgi SNAP receptor complex member 2 K08496|1|1e-104|384|mmu:56494|golgi SNAP receptor complex member 2 GO:0012505//endomembrane system;GO:0044431//Golgi apparatus part;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane - GO:0045184//establishment of protein localization;GO:0006810//transport gi|2316092|gb|AAB82653.1|/1.01696e-103/golgi SNARE [Mus musculus] 66743 1952.3 25.03 26.01333333 0.055592986 Up 0.182772951 Rnf220 ring finger protein 220 - GO:0044424;GO:0044424 GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0016567//protein ubiquitination;GO:0016567//protein ubiquitination gi|37059808|ref|NP_080015.3|/5.12328e-145/E3 ubiquitin-protein ligase Rnf220 isoform 1 [Mus musculus] 15239 2906.22 24.60333333 25.58333333 0.05635046 Up 0.182772951 Hgs HGF-regulated tyrosine kinase substrate K12182|1|0.0|1346|mmu:15239|hepatocyte growth factor-regulated tyrosine kinase substrate "GO:0005771//multivesicular body;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005769//early endosome;GO:0005771//multivesicular body;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005769//early endosome" "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0043169//cation binding;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0043169//cation binding;GO:0005515//protein binding" GO:0007041//lysosomal transport;GO:0007259//JAK-STAT cascade;GO:0006796//phosphate-containing compound metabolic process;GO:0015031//protein transport;GO:0007041//lysosomal transport;GO:0007259//JAK-STAT cascade;GO:0006796//phosphate-containing compound metabolic process;GO:0015031//protein transport gi|564375670|ref|XP_006247970.1|/0/PREDICTED: hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1 [Rattus norvegicus] 14755 3126.11 23.73 22.75666667 -0.060422849 Down 0.182641318 Pigq "phosphatidylinositol glycan anchor biosynthesis, class Q" "K03860|1|0.0|1076|mmu:14755|phosphatidylinositol glycan, class Q" GO:0043234//protein complex;GO:0016020//membrane;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity GO:0006497//protein lipidation;GO:0006497//protein lipidation gi|31981380|ref|NP_035952.2|/0/phosphatidylinositol N-acetylglucosaminyltransferase subunit Q isoform 2 [Mus musculus] 230103 3660 23.98666667 23.01333333 -0.059762722 Down 0.182641318 Npr2 natriuretic peptide receptor 2 K12324|1|0.0|1996|mmu:230103|atrial natriuretic peptide receptor B [EC:4.6.1.2] GO:0031224//intrinsic component of membrane GO:0016301//kinase activity;GO:0032550;GO:0005515//protein binding;GO:0001653//peptide receptor activity;GO:0042277//peptide binding;GO:0016829//lyase activity;GO:0009975//cyclase activity GO:0001501//skeletal system development;GO:0009152//purine ribonucleotide biosynthetic process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0071345//cellular response to cytokine stimulus;GO:0006464//cellular protein modification process gi|743715094|ref|XP_010951157.1|/0/PREDICTED: LOW QUALITY PROTEIN: atrial natriuretic peptide receptor 2 [Camelus bactrianus] 434484 2417 23.05 22.07666667 -0.062244393 Down 0.182641318 Sp140 Sp140 nuclear body protein K15413|1|5e-87|325|rro:104656168|nuclear autoantigen Sp-100 GO:0031981//nuclear lumen GO:0046872//metal ion binding - gi|62000674|ref|NP_001013839.1|/0/SP140 nuclear body protein family member [Mus musculus] 76566 3533 23.21333333 22.24 -0.061796914 Down 0.182641318 Fam101b "family with sequence similarity 101, member B" - GO:0005856//cytoskeleton GO:0008092//cytoskeletal protein binding GO:0007010//cytoskeleton organization;GO:0000904//cell morphogenesis involved in differentiation gi|268370105|ref|NP_083934.1|/4.99865e-102/filamin-interacting protein FAM101B [Mus musculus] 20872 2885 21.27333333 22.24 0.06411068 Up 0.182641318 Stk16 serine/threonine kinase 16 K08856|1|3e-167|592|mmu:20872|serine/threonine kinase 16 [EC:2.7.11.1] "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0016023//cytoplasmic, membrane-bounded vesicle" "GO:0032550;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0004713//protein tyrosine kinase activity;GO:0032550;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0004713//protein tyrosine kinase activity;GO:0032550;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0004713//protein tyrosine kinase activity" GO:0071363//cellular response to growth factor stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0071363//cellular response to growth factor stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0071363//cellular response to growth factor stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0006468//protein phosphorylation gi|226958539|ref|NP_035624.3|/2.28746e-166/serine/threonine-protein kinase 16 [Mus musculus] 72075 2306 24.52 25.48666667 0.05578372 Up 0.182641318 Ogfr opioid growth factor receptor K00907|1|6e-28|128|myb:102259949|myosin-light-chain kinase [EC:2.7.11.18] GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle - GO:0040007//growth gi|258679484|ref|NP_113550.3|/0/opioid growth factor receptor [Mus musculus] 15526 3067 266.4233333 276.0133333 0.051017522 Up 0.182575501 Hspa9 heat shock protein 9 K04043|1|0.0|1160|mmu:15526|molecular chaperone DnaK GO:0031981//nuclear lumen;GO:0005759//mitochondrial matrix GO:0032550;GO:0019838//growth factor binding GO:0044267//cellular protein metabolic process;GO:0006886//intracellular protein transport "gi|162461907|ref|NP_034611.2|/0/stress-70 protein, mitochondrial [Mus musculus]" 230101 3552 11.56333333 10.98666667 -0.073803598 Down 0.182528489 Gba2 glucosidase beta 2 K17108|1|0.0|1833|mmu:230101|non-lysosomal glucosylceramidase [EC:3.2.1.45] GO:0031224//intrinsic component of membrane;GO:0005783//endoplasmic reticulum GO:0015926//glucosidase activity GO:0016137//glycoside metabolic process;GO:0006678//glucosylceramide metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0008202//steroid metabolic process gi|50511011|dbj|BAD32491.1|/0/mKIAA1605 protein [Mus musculus] 20364 722 252.1566667 242.9066667 -0.053918283 Down 0.182481477 Sepw1 "selenoprotein W, muscle 1" - - - - - 100642166 1551 0.1 0.186666667 0.900464326 Up 0.182481477 Gm15446 predicted gene 15446 K09228|1|2e-26|122|mmu:102632383|KRAB domain-containing zinc finger protein - - - - 64292 3647 0.19 0.293333333 0.626541604 Up 0.182443868 Ptges prostaglandin E synthase K15729|1|5e-83|312|mmu:64292|microsomal prostaglandin-E synthase 1 [EC:5.3.99.3] GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0005635//nuclear envelope GO:0016860//intramolecular oxidoreductase activity;GO:0072341//modified amino acid binding GO:0033993//response to lipid;GO:0006693//prostaglandin metabolic process;GO:0010038//response to metal ion;GO:0006954//inflammatory response;GO:0002237//response to molecule of bacterial origin;GO:0008283//cell proliferation gi|11967941|ref|NP_071860.1|/4.56281e-82/prostaglandin E synthase [Mus musculus] 225887 843.67 268.61 259.7533333 -0.048370753 Down 0.182425063 Ndufs8 NADH dehydrogenase (ubiquinone) Fe-S protein 8 K03941|1|7e-112|405|mmu:225887|NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0050136//NADH dehydrogenase (quinone) activity;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0050136//NADH dehydrogenase (quinone) activity;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0050136//NADH dehydrogenase (quinone) activity GO:0044710;GO:0010257//NADH dehydrogenase complex assembly;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization;GO:0006950//response to stress;GO:0044710;GO:0010257//NADH dehydrogenase complex assembly;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization;GO:0006950//response to stress;GO:0044710;GO:0010257//NADH dehydrogenase complex assembly;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization;GO:0006950//response to stress "gi|46195430|ref|NP_659119.2|/6.12568e-111/NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial [Mus musculus]" 235040 3024 23.47333333 24.43 0.057631137 Up 0.182406258 Atg4d "autophagy related 4D, cysteine peptidase" K08342|1|0.0|907|mmu:235040|cysteine protease ATG4 [EC:3.4.22.-] GO:0044424 "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0044248;GO:0019538//protein metabolic process;GO:0045184//establishment of protein localization gi|29135261|ref|NP_705811.8|/0/cysteine protease ATG4D precursor [Mus musculus] 26968 2115.53 22.28333333 23.24666667 0.061058804 Up 0.182406258 Islr immunoglobulin superfamily containing leucine-rich repeat K16357|1|1e-28|130|bfo:BRAFLDRAFT_84652|leucine-rich repeat and fibronectin type-III domain-containing protein 4;K16354|2|1e-26|124|bfo:BRAFLDRAFT_89096|leucine-rich repeat and fibronectin type-III domain-containing protein 1;K19511|3|1e-24|117|dan:Dana_GF10247|peroxidase [EC:1.11.1.7] - - - "gi|148693990|gb|EDL25937.1|/0/immunoglobulin superfamily containing leucine-rich repeat, isoform CRA_a, partial [Mus musculus]" 58522 1548 260.6733333 268.9333333 0.045005579 Up 0.182359246 Trim54 tripartite motif-containing 54 K10653|1|0.0|638|mmu:58522|tripartite motif-containing protein 54 GO:0015630//microtubule cytoskeleton;GO:0031674//I band GO:0046914//transition metal ion binding;GO:0015631//tubulin binding GO:0007019//microtubule depolymerization;GO:0048869//cellular developmental process gi|10946824|ref|NP_067422.1|/1.28351e-180/tripartite motif-containing protein 54 [Mus musculus] 68026 2387 0.813333333 0.963333333 0.244188345 Up 0.182312234 2810417H13Rik RIKEN cDNA 2810417H13 gene - - - - - 66552 5629 7.943333333 8.376666667 0.07663172 Up 0.182284027 Sppl2a signal peptide peptidase like 2A K09596|1|0.0|904|mmu:66552|signal peptide peptidase-like 2A [EC:3.4.23.-] GO:0005764//lysosome;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0000139//Golgi membrane;GO:0005770//late endosome GO:0042802//identical protein binding;GO:0016787//hydrolase activity GO:0002682//regulation of immune system process;GO:0033619//membrane protein proteolysis gi|258645125|ref|NP_075709.2|/0/signal peptide peptidase-like 2A precursor [Mus musculus] 66388 1296 7.45 7.876666667 0.080344798 Up 0.182284027 Cutc cutC copper transporter K06201|1|2e-150|534|mmu:66388|copper homeostasis protein - - - - 18415 3576 7.866666667 7.44 -0.080449832 Down 0.182284027 Hspa4l heat shock protein 4 like K09485|1|0.0|1677|mmu:18415|heat shock protein 110kDa GO:0043231//intracellular membrane-bounded organelle GO:0032550 GO:0044267//cellular protein metabolic process;GO:0035966//response to topologically incorrect protein "gi|148703191|gb|EDL35138.1|/0/heat shock protein 4 like, isoform CRA_c, partial [Mus musculus]" 216161 4679 7.683333333 8.11 0.07796957 Up 0.182284027 Sbno2 strawberry notch homolog 2 (Drosophila) K04425|1|4e-06|57.4|pss:102456989|mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25] - - "GO:0006954//inflammatory response;GO:0002275//myeloid cell activation involved in immune response;GO:0006351//transcription, DNA-templated" "gi|148699657|gb|EDL31604.1|/0/strawberry notch homolog (Drosophila), isoform CRA_c, partial [Mus musculus]" 58240 2958 7.563333333 7.996666667 0.080376549 Up 0.182284027 Hs1bp3 HCLS1 binding protein 3 - - - - "gi|148665986|gb|EDK98402.1|/0/HS1 binding protein 3, isoform CRA_a, partial [Mus musculus]" 14733 3552 229.3933333 221.64 -0.049605192 Down 0.182227613 Gpc1 glypican 1 K08107|1|0.0|1028|mmu:14733|glypican 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0031012//extracellular matrix GO:0046914//transition metal ion binding;GO:0019838//growth factor binding;GO:0043168//anion binding;GO:0005518//collagen binding GO:0035914//skeletal muscle cell differentiation;GO:0007422//peripheral nervous system development;GO:0010927;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0030167//proteoglycan catabolic process gi|7710028|ref|NP_057905.1|/0/glypican-1 precursor [Mus musculus] 107817 1688 20.83333333 21.78666667 0.064551794 Up 0.182208808 Jmjd6 jumonji domain containing 6 K11323|1|0.0|774|mmu:107817|histone arginine demethylase JMJD6 [EC:1.14.11.-] GO:0031981//nuclear lumen;GO:0016020//membrane "GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0032452//histone demethylase activity;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0003723//RNA binding" "GO:0001525//angiogenesis;GO:0006351//transcription, DNA-templated;GO:0030217//T cell differentiation;GO:0002274;GO:0043010//camera-type eye development;GO:0012501//programmed cell death;GO:0070077;GO:0030323//respiratory tube development;GO:0007165//signal transduction;GO:0006910//phagocytosis, recognition;GO:0030218//erythrocyte differentiation;GO:0000398//mRNA splicing, via spliceosome;GO:0017185//peptidyl-lysine hydroxylation" gi|125988379|ref|NP_203971.2|/0/bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 [Mus musculus] 104816 2732 0.18 0.276666667 0.620151929 Up 0.182208808 Aspg asparaginase K13278|1|0.0|1055|mmu:104816|60kDa lysophospholipase [EC:3.1.1.5 3.1.1.47 3.5.1.1] - - - - 22627 2078 217.3733333 225.0966667 0.050369727 Up 0.182208808 Ywhae "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide" K06630|1|3e-137|491|cmy:102944738|14-3-3 protein epsilon GO:0048770;GO:0030424//axon;GO:0005875//microtubule associated complex GO:0016597//amino acid binding;GO:0016491//oxidoreductase activity;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0019899//enzyme binding GO:0044772//mitotic cell cycle phase transition;GO:0012501//programmed cell death;GO:0006886//intracellular protein transport;GO:0021543//pallium development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044710;GO:0006470//protein dephosphorylation;GO:0016477//cell migration;GO:0035556//intracellular signal transduction gi|5803225|ref|NP_006752.1|/2.18023e-136/14-3-3 protein epsilon [Homo sapiens] 170752 2093 0.186666667 0.286666667 0.618909833 Up 0.182208808 Bco2 beta-carotene oxygenase 2 "K10252|1|0.0|1106|mmu:170752|beta,beta-carotene 9',10'-dioxygenase [EC:1.13.11.71]" GO:0043231//intracellular membrane-bounded organelle "GO:0043169//cation binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0001523//retinoid metabolic process;GO:0031323//regulation of cellular metabolic process;GO:0016108;GO:0042391//regulation of membrane potential;GO:0016119//carotene metabolic process "gi|18875374|ref|NP_573480.1|/0/beta,beta-carotene 9',10'-oxygenase [Mus musculus]" 338350 2375 25.24 24.29 -0.05534942 Down 0.182208808 Acad12 "acyl-Coenzyme A dehydrogenase family, member 12" K11729|1|0.0|905|mmu:71985|acyl-CoA dehydrogenase family member 10 GO:0043231//intracellular membrane-bounded organelle GO:0016491//oxidoreductase activity;GO:0000166//nucleotide binding;GO:0016740//transferase activity GO:0044710 "gi|257467675|ref|NP_848914.2|/0/acyl-Coenzyme A dehydrogenase family, member 10-like [Mus musculus]" 67996 3547 24.25 25.19666667 0.055248141 Up 0.182208808 Srsf6 serine/arginine-rich splicing factor 6 "K12893|1|3e-82|309|rno:362264|splicing factor, arginine/serine-rich 4/5/6" GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0036094//small molecule binding GO:0000245//spliceosomal complex assembly;GO:0006405//RNA export from nucleus;GO:0006366//transcription from RNA polymerase II promoter gi|62087532|dbj|BAD92213.1|/2.19407e-81/arginine/serine-rich splicing factor 6 variant [Homo sapiens] 233900 4172 23.89666667 22.94333333 -0.058734382 Down 0.182208808 Rnf40 ring finger protein 40 K10696|1|0.0|1771|mmu:233900|E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27] GO:0031981//nuclear lumen;GO:0042995//cell projection;GO:0000151//ubiquitin ligase complex;GO:0016020//membrane GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0019905//syntaxin binding;GO:0019787//ubiquitin-like protein transferase activity GO:0016574//histone ubiquitination;GO:0019941//modification-dependent protein catabolic process;GO:0006513//protein monoubiquitination gi|37360032|dbj|BAC97994.1|/0/mKIAA0661 protein [Mus musculus] 330301 2829 0.383333333 0.276666667 -0.47045062 Down 0.182171199 Zfp786 zinc finger protein 786 K09228|1|0.0|1635|mmu:330301|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|29244498|ref|NP_808550.1|/0/zinc finger protein 786 [Mus musculus] 329831 1271 0.826666667 0.683333333 -0.274716211 Down 0.182152394 Fam166b "family with sequence similarity 166, member B" - - - - gi|193806567|sp|A2AIP0.1|F166B_MOUSE/8.61992e-145/RecName: Full=Protein FAM166B 14089 2704 0.81 0.673333333 -0.266601021 Down 0.182152394 Fap fibroblast activation protein "K08674|1|0.0|1586|mmu:14089|fibroblast activation protein, alpha [EC:3.4.21.-]" GO:0031224//intrinsic component of membrane;GO:0031253//cell projection membrane;GO:0030027//lamellipodium;GO:0044421 GO:0004175//endopeptidase activity;GO:0008238//exopeptidase activity;GO:0042802//identical protein binding;GO:0019899//enzyme binding GO:0016477//cell migration;GO:0042730//fibrinolysis;GO:0019538//protein metabolic process;GO:0010715//regulation of extracellular matrix disassembly gi|6679749|ref|NP_032012.1|/0/prolyl endopeptidase FAP [Mus musculus] 74069 1204 0.206666667 0.113333333 -0.866733469 Down 0.182152394 Serpina3a "serine (or cysteine) peptidase inhibitor, clade A, member 3A" "K04525|1|6e-129|462|mmu:74069|serpin peptidase inhibitor, clade A" - - - gi|13386342|ref|NP_083016.1|/5.20325e-128/serine protease inhibitor A3A isoform 2 [Mus musculus] 12034 1360 218.9033333 226.3266667 0.048112655 Up 0.182142991 Phb2 prohibitin 2 K17081|1|9e-140|499|ocu:100341779|prohibitin 2 GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0035258//steroid hormone receptor binding "GO:0006351//transcription, DNA-templated;GO:0033598//mammary gland epithelial cell proliferation;GO:0003006//developmental process involved in reproduction;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0060444//branching involved in mammary gland duct morphogenesis" gi|532105559|ref|XP_005338365.1|/7.83064e-139/PREDICTED: prohibitin-2 [Ictidomys tridecemlineatus] 14678 2177 194.8833333 202.1166667 0.052577577 Up 0.182114784 Gnai2 "guanine nucleotide binding protein (G protein), alpha inhibiting 2" K04630|1|0.0|716|nle:100588993|guanine nucleotide-binding protein G(i) subunit alpha - - - gi|472359423|ref|XP_004399328.1|/0/PREDICTED: guanine nucleotide-binding protein G(i) subunit alpha-2 isoform X1 [Odobenus rosmarus divergens] 19045 1363 191.29 198.1866667 0.05109845 Up 0.182011358 Ppp1ca "protein phosphatase 1, catalytic subunit, alpha isoform" K06269|1|0.0|680|mmu:19045|serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] GO:0008287//protein serine/threonine phosphatase complex;GO:0030425//dendrite;GO:0035097//histone methyltransferase complex;GO:0043025//neuronal cell body;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding GO:0007010//cytoskeleton organization;GO:0005980//glycogen catabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006412//translation;GO:0006796//phosphate-containing compound metabolic process;GO:0005978//glycogen biosynthetic process;GO:0007126//meiotic nuclear division;GO:0030323//respiratory tube development;GO:0060562//epithelial tube morphogenesis;GO:0006464//cellular protein modification process;GO:0006641//triglyceride metabolic process gi|478527148|ref|XP_004437757.1|/0/PREDICTED: serine/threonine-protein phosphatase PP1-alpha catalytic subunit [Ceratotherium simum simum] 20955 2595 1.876666667 2.083333333 0.150721267 Up 0.181992553 Vamp7 vesicle-associated membrane protein 7 K08515|1|2e-111|406|mmu:20955|vesicle-associated membrane protein 7 GO:0030133//transport vesicle;GO:0030666//endocytic vesicle membrane;GO:0005764//lysosome;GO:0005770//late endosome;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0042995//cell projection;GO:0030133//transport vesicle;GO:0030666//endocytic vesicle membrane;GO:0005764//lysosome;GO:0005770//late endosome;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0042995//cell projection GO:0000149//SNARE binding;GO:0000149//SNARE binding GO:0006909//phagocytosis;GO:0002283//neutrophil activation involved in immune response;GO:0016482//cytosolic transport;GO:0006906//vesicle fusion;GO:0002278;GO:0006887//exocytosis;GO:0033157//regulation of intracellular protein transport;GO:0007041//lysosomal transport;GO:0048193//Golgi vesicle transport;GO:0034196//acylglycerol transport;GO:0006909//phagocytosis;GO:0002283//neutrophil activation involved in immune response;GO:0016482//cytosolic transport;GO:0006906//vesicle fusion;GO:0002278;GO:0006887//exocytosis;GO:0033157//regulation of intracellular protein transport;GO:0007041//lysosomal transport;GO:0034196//acylglycerol transport gi|33468929|ref|NP_035645.1|/2.74482e-92/vesicle-associated membrane protein 7 isoform 1 [Mus musculus] 630836 2625 1.903333333 2.113333333 0.150992095 Up 0.181992553 2010315B03Rik RIKEN cDNA 2010315B03 gene K09228|1|0.0|659|mmu:628709|KRAB domain-containing zinc finger protein - - - gi|340805875|ref|NP_001230048.1|/0/RIKEN cDNA 2010315B03 isoform 3 [Mus musculus] 320560 9833 1.92 2.13 0.14974712 Up 0.181992553 Dennd5b DENN/MADD domain containing 5B K20164|1|0.0|2422|mmu:320560|DENN domain-containing protein 5 - - - gi|145580623|ref|NP_796166.2|/0/DENN domain-containing protein 5B [Mus musculus] 236792 4084 11.76333333 11.19666667 -0.071227635 Down 0.181983151 Mmgt1 membrane magnesium transporter 1 "K18163|1|3e-11|74.3|loa:LOAG_08427|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 6;K03847|2|7e-09|66.2|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005769//early endosome GO:0005381//iron ion transmembrane transporter activity GO:0006826//iron ion transport;GO:0070838//divalent metal ion transport gi|537128404|gb|ERE65414.1|/5.74015e-65/protein DDX26B-like protein [Cricetulus griseus] 110109 2626 11.9 11.33 -0.070813712 Down 0.181983151 Nop2 NOP2 nucleolar protein K14835|1|0.0|1423|mmu:110109|ribosomal RNA methyltransferase Nop2 [EC:2.1.1.-] - - - - 100316870 12530 11.74 12.31 0.068398353 Up 0.181983151 Gm17821 DDB1 and CUL4 associated factor 5 pseudogene K11800|1|2e-96|115|mmu:320808|WD repeat-containing protein 22 - - - gi|16508047|gb|AAL17972.1|/0/pORF2 [Mus musculus domesticus] 52521 2804 12.02333333 12.59333333 0.066823279 Up 0.181983151 Zfp622 zinc finger protein 622 K14816|1|0.0|837|mmu:52521|pre-60S factor REI1 GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0006979//response to oxidative stress;GO:0007254//JNK cascade;GO:0006915//apoptotic process;GO:0043549//regulation of kinase activity gi|21362307|ref|NP_653106.1|/0/zinc finger protein 622 [Mus musculus] 373852 2619.34 1.32 1.15 -0.198904068 Down 0.181842115 4833422C13Rik RIKEN cDNA 4833422C13 gene K01067|1|6e-16|88.6|mmu:74156|acetyl-CoA hydrolase [EC:3.1.2.1] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0016289//CoA hydrolase activity;GO:0032550;GO:0052689//carboxylic ester hydrolase activity;GO:0016289//CoA hydrolase activity;GO:0032550;GO:0052689//carboxylic ester hydrolase activity GO:0006637//acyl-CoA metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0044238//primary metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0044238//primary metabolic process gi|37361850|gb|AAQ91038.1|/1.98454e-45/LRRGT00082 [Rattus norvegicus] 72852 3881 1.136666667 1.31 0.204757573 Up 0.181842115 Mblac2 metallo-beta-lactamase domain containing 2 K14026|1|1e-30|138|ocu:100353303|SEL1 protein - GO:0043169//cation binding;GO:0003824//catalytic activity - gi|76677920|ref|NP_082648.1|/2.21506e-159/metallo-beta-lactamase domain-containing protein 2 [Mus musculus] 80719 2133 1.27 1.103333333 -0.202959781 Down 0.181842115 Igsf6 "immunoglobulin superfamily, member 6" - GO:0031224//intrinsic component of membrane - - gi|13540503|ref|NP_109616.1|/3.95811e-133/immunoglobulin superfamily member 6 precursor [Mus musculus] 546336 3877 1.143333333 1.316666667 0.203644077 Up 0.181842115 Prrg1 proline rich Gla (G-carboxyglutamic acid) 1 K01314|1|2e-18|97.8|mdo:100022394|coagulation factor X [EC:3.4.21.6] - - - gi|569010364|ref|XP_006528208.1|/1.8266e-108/PREDICTED: transmembrane gamma-carboxyglutamic acid protein 1 isoform X2 [Mus musculus] 320438 3114 1.096666667 1.263333333 0.204110264 Up 0.181842115 Alg6 "asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase)" "K03848|1|0.0|956|mmu:320438|alpha-1,3-glucosyltransferase [EC:2.4.1.267]" GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0016758//transferase activity, transferring hexosyl groups" GO:0006486//protein glycosylation "gi|124486913|ref|NP_001074733.1|/0/dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase precursor [Mus musculus]" 68813 10335 1.156666667 1.33 0.201453084 Up 0.181842115 Dock5 dedicator of cytokinesis 5 K17707|1|0.0|3590|mmu:68813|dedicator of cytokinesis protein 5 GO:0044424 GO:0030695//GTPase regulator activity GO:0035556//intracellular signal transduction gi|124358946|ref|NP_808448.2|/0/dedicator of cytokinesis protein 5 [Mus musculus] 116905 2103 4.29 4.596666667 0.099610403 Up 0.181795103 Dph1 diphthamide biosynthesis 1 K07561|1|0.0|884|mmu:116905|2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108] - - - - 15258 4187.59 4.213333333 4.526666667 0.103487016 Up 0.181795103 Hipk2 homeodomain interacting protein kinase 2 K08826|1|0.0|2069|mmu:15258|homeodomain interacting protein kinase [EC:2.7.11.1] GO:0016604//nuclear body;GO:0005635//nuclear envelope;GO:0005815//microtubule organizing center;GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0005635//nuclear envelope;GO:0005815//microtubule organizing center;GO:0016604//nuclear body;GO:0005635//nuclear envelope;GO:0005815//microtubule organizing center GO:0004672//protein kinase activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0004672//protein kinase activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0004672//protein kinase activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0004672//protein kinase activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0032550;GO:0003676//nucleic acid binding "GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0050881//musculoskeletal movement;GO:0002089//lens morphogenesis in camera-type eye;GO:0007254//JNK cascade;GO:0030509//BMP signaling pathway;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0008344//adult locomotory behavior;GO:0043393//regulation of protein binding;GO:0031076//embryonic camera-type eye development;GO:0030154//cell differentiation;GO:0008283//cell proliferation;GO:0001525//angiogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0003002//regionalization;GO:0051099//positive regulation of binding;GO:0043066//negative regulation of apoptotic process;GO:0048598//embryonic morphogenesis;GO:0003407//neural retina development;GO:0006468//protein phosphorylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0050881//musculoskeletal movement;GO:0002089//lens morphogenesis in camera-type eye;GO:0007254//JNK cascade;GO:0030509//BMP signaling pathway;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0008344//adult locomotory behavior;GO:0043393//regulation of protein binding;GO:0031076//embryonic camera-type eye development;GO:0030154//cell differentiation;GO:0008283//cell proliferation;GO:0001525//angiogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0003002//regionalization;GO:0051099//positive regulation of binding;GO:0043066//negative regulation of apoptotic process;GO:0048598//embryonic morphogenesis;GO:0003407//neural retina development;GO:0006468//protein phosphorylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0050881//musculoskeletal movement;GO:0002089//lens morphogenesis in camera-type eye;GO:0007254//JNK cascade;GO:0030509//BMP signaling pathway;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0008344//adult locomotory behavior;GO:0043393//regulation of protein binding;GO:0031076//embryonic camera-type eye development;GO:0030154//cell differentiation;GO:0008283//cell proliferation;GO:0001525//angiogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0003002//regionalization;GO:0051099//positive regulation of binding;GO:0043066//negative regulation of apoptotic process;GO:0048598//embryonic morphogenesis;GO:0003407//neural retina development;GO:0006468//protein phosphorylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0050881//musculoskeletal movement;GO:0002089//lens morphogenesis in camera-type eye;GO:0007254//JNK cascade;GO:0030509//BMP signaling pathway;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0008344//adult locomotory behavior;GO:0043393//regulation of protein binding;GO:0031076//embryonic camera-type eye development;GO:0030154//cell differentiation;GO:0008283//cell proliferation;GO:0001525//angiogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0003002//regionalization;GO:0051099//positive regulation of binding;GO:0043066//negative regulation of apoptotic process;GO:0048598//embryonic morphogenesis;GO:0003407//neural retina development;GO:0006468//protein phosphorylation" gi|659066193|ref|NP_001281072.1|/0/homeodomain-interacting protein kinase 2 isoform 3 [Mus musculus] 18779 7112 0.4 0.29 -0.4639471 Down 0.181795103 Pla2r1 phospholipase A2 receptor 1 "K06560|1|0.0|3082|mmu:18779|mannose receptor, C type" GO:0016021//integral component of membrane;GO:0044464 GO:0019899//enzyme binding "GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0010519//negative regulation of phospholipase activity;GO:0034599//cellular response to oxidative stress;GO:0032305//positive regulation of icosanoid secretion;GO:0007569//cell aging;GO:0032304//negative regulation of icosanoid secretion;GO:0006897//endocytosis;GO:0044237//cellular metabolic process;GO:0044707" gi|148695017|gb|EDL26964.1|/0/phospholipase A2 receptor 1 [Mus musculus] 234311 5994 0.286666667 0.393333333 0.456378295 Up 0.181795103 Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 K20103|1|0.0|3356|mmu:234311|ATP-dependent RNA helicase DDX60 [EC:3.6.4.13] - - - gi|657940862|ref|NP_001280712.1|/0/probable ATP-dependent RNA helicase DDX60 [Mus musculus] 19671 1446 4.69 4.383333333 -0.097559529 Down 0.181795103 Rce1 Ras converting CAAX endopeptidase 1 K08658|1|7e-149|529|mmu:19671|prenyl protein peptidase [EC:3.4.22.-] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0004175//endopeptidase activity GO:0016485//protein processing gi|511879172|ref|XP_004759523.1|/1.3003e-161/PREDICTED: CAAX prenyl protease 2 isoform X1 [Mustela putorius furo] 76889 2190 4.87 4.556666667 -0.095942935 Down 0.181795103 Adck4 coenzyme Q8B K08869|1|0.0|968|mmu:76889|aarF domain-containing kinase GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity GO:0006796//phosphate-containing compound metabolic process "gi|148692246|gb|EDL24193.1|/0/aarF domain containing kinase 4, isoform CRA_a, partial [Mus musculus]" 238799 5389.44 4.55 4.86 0.095089769 Up 0.181795103 Tnpo1 transportin 1 K18752|1|0.0|1729|mmu:238799|transportin-1 GO:0044444//cytoplasmic part;GO:0005635//nuclear envelope;GO:0044444//cytoplasmic part;GO:0005635//nuclear envelope GO:0022892//substrate-specific transporter activity;GO:0005048//signal sequence binding;GO:0022892//substrate-specific transporter activity;GO:0005048//signal sequence binding GO:0016070//RNA metabolic process;GO:0006606//protein import into nucleus;GO:0016070//RNA metabolic process;GO:0006606//protein import into nucleus gi|537233715|gb|ERE84710.1|/0/transportin-1-like protein [Cricetulus griseus] 67967 3002 4.063333333 4.37 0.10496956 Up 0.181795103 Pold3 "polymerase (DNA-directed), delta 3, accessory subunit" K03504|1|0.0|719|mmu:67967|DNA polymerase delta subunit 3 GO:0031981//nuclear lumen;GO:0042575 "GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006260//DNA replication "gi|148684474|gb|EDL16421.1|/0/polymerase (DNA-directed), delta 3, accessory subunit, isoform CRA_b, partial [Mus musculus]" 58234 7131 21.42 20.48666667 -0.064273214 Down 0.181785701 Shank3 SH3/ankyrin domain gene 3 K15009|1|0.0|2643|mmu:58234|SH3 and multiple ankyrin repeat domains protein - - - - 17258 5540.83 20.18666667 21.11333333 0.064751662 Up 0.181785701 Mef2a myocyte enhancer factor 2A K09260|1|0.0|774|cge:100766678|MADS-box transcription enhancer factor 2A GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen;GO:0000785//chromatin "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0019900//kinase binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0008016//regulation of heart contraction;GO:0012501//programmed cell death;GO:0055003//cardiac myofibril assembly;GO:0051592//response to calcium ion;GO:0000165//MAPK cascade;GO:0007005//mitochondrion organization;GO:0016358//dendrite development;GO:0006366//transcription from RNA polymerase II promoter;GO:0008016//regulation of heart contraction;GO:0012501//programmed cell death;GO:0055003//cardiac myofibril assembly;GO:0051592//response to calcium ion;GO:0000165//MAPK cascade;GO:0007005//mitochondrion organization;GO:0001678//cellular glucose homeostasis;GO:0006366//transcription from RNA polymerase II promoter;GO:0008016//regulation of heart contraction;GO:0012501//programmed cell death;GO:0055003//cardiac myofibril assembly;GO:0051592//response to calcium ion;GO:0000165//MAPK cascade;GO:0007005//mitochondrion organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0008016//regulation of heart contraction;GO:0055003//cardiac myofibril assembly;GO:0051592//response to calcium ion;GO:0000165//MAPK cascade;GO:0007005//mitochondrion organization;GO:0016358//dendrite development;GO:0006366//transcription from RNA polymerase II promoter;GO:0008016//regulation of heart contraction;GO:0012501//programmed cell death;GO:0055003//cardiac myofibril assembly;GO:0051592//response to calcium ion;GO:0000165//MAPK cascade;GO:0007005//mitochondrion organization;GO:0001678//cellular glucose homeostasis gi|600971656|ref|NP_001278124.1|/0/myocyte-specific enhancer factor 2A isoform c [Mus musculus] 93761 4024 0.303333333 0.2 -0.600904045 Down 0.181729287 Smarca1 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1" K11727|1|0.0|1951|rno:317575|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1 [EC:3.6.4.-] - - - - 224344 2699 0.303333333 0.2 -0.600904045 Down 0.181729287 Rbm11 RNA binding motif protein 11 K13188|1|1e-27|128|lcm:102353062|RNA-binding protein 7 GO:0043231//intracellular membrane-bounded organelle GO:0036094//small molecule binding;GO:0003676//nucleic acid binding GO:0048869//cellular developmental process;GO:0006396//RNA processing "gi|148665852|gb|EDK98268.1|/2.54459e-137/RNA binding motif protein 11, isoform CRA_a [Mus musculus]" 217294 1952 0.193333333 0.293333333 0.601450624 Up 0.181729287 BC006965 cDNA sequence BC006965 K10367|1|1e-06|57.8|mmu:14260|formin 1 - - - - 192653 789 0.2 0.303333333 0.600904045 Up 0.181729287 Ttc36 tetratricopeptide repeat domain 36 K09186|1|1e-44|182|lcm:102357046|histone-lysine N-methyltransferase MLL1 [EC:2.1.1.43] - - - gi|20336734|ref|NP_620401.1|/1.84467e-86/tetratricopeptide repeat protein 36 [Mus musculus] 21819 8462 0.29 0.193333333 -0.584962501 Down 0.181729287 Tg thyroglobulin K10809|1|0.0|5587|mmu:21819|thyroglobulin - - - "gi|148697428|gb|EDL29375.1|/0/thyroglobulin, isoform CRA_b, partial [Mus musculus]" 20521 2255 0.196666667 0.296666667 0.593090382 Up 0.181729287 Slc22a12 "solute carrier family 22 (organic anion/cation transporter), member 12" "K08208|1|0.0|1050|mmu:20521|MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 12" GO:0044459;GO:0005903//brush border;GO:0031224//intrinsic component of membrane GO:0005342//organic acid transmembrane transporter activity;GO:0019904//protein domain specific binding GO:0044763;GO:0015711//organic anion transport;GO:0042221//response to chemical;GO:0006082//organic acid metabolic process gi|165377219|ref|NP_033229.3|/0/solute carrier family 22 member 12 [Mus musculus] 101488212 3964 0.203333333 0.303333333 0.577057303 Up 0.181729287 Gm21975 predicted gene 21975 K16854|1|0.0|690|mmu:216984|ecotropic viral integration site 2B protein GO:0044424;GO:0016021//integral component of membrane - - gi|22122501|ref|NP_666135.1|/0/protein EVI2B precursor [Mus musculus] 72612 1210 5.746666667 6.103333333 0.086872017 Up 0.181682275 2700029M09Rik histone PARylation factor 1 - - - - "gi|148696693|gb|EDL28640.1|/0/mCG14817, isoform CRA_d, partial [Mus musculus]" 66205 1363 5.966666667 5.603333333 -0.090639863 Down 0.181682275 Cd302 CD302 antigen K06722|1|4e-113|410|mmu:66205|CD302 antigen;K06559|3|7e-95|350|cge:100769089|lymphocyte antigen 75 GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding GO:0006897//endocytosis;GO:0006897//endocytosis gi|594591610|ref|NP_001277589.1|/9.64803e-121/CD302 antigen isoform a precursor [Mus musculus] 217705 3357 6.19 5.833333333 -0.085618893 Down 0.181682275 Fam161b "family with sequence similarity 161, member B" K16772|1|4e-52|209|dre:558320|protein FAM161A - - - "gi|148670839|gb|EDL02786.1|/0/RIKEN cDNA 9830169C18, isoform CRA_b, partial [Mus musculus]" 67225 2565.93 2.493333333 2.27 -0.135383472 Down 0.181682275 Rnpc3 "RNA-binding region (RNP1, RRM) containing 3" K13157|1|0.0|890|mmu:67225|U11/U12 small nuclear ribonucleoprotein 65 kDa protein GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding - gi|560186546|ref|NP_001273944.1|/0/RNA-binding protein 40 isoform b [Mus musculus] 210529 2625 6.093333333 5.733333333 -0.087857505 Down 0.181682275 Mettl14 methyltransferase like 14 K05925|1|0.0|688|mmu:210529|mRNA (2'-O-methyladenosine-N6-)-methyltransferase [EC:2.1.1.62] - GO:0016741 GO:0006725//cellular aromatic compound metabolic process gi|260099682|ref|NP_964000.2|/0/N6-adenosine-methyltransferase subunit METTL14 [Mus musculus] 22439 5062 2.16 2.376666667 0.137908264 Up 0.181682275 Xk X-linked Kx blood group K19522|1|0.0|897|mmu:22439|membrane transport protein XK - - - - 211488 4456 5.97 5.613333333 -0.088873199 Down 0.181682275 Ado 2-aminoethanethiol (cysteamine) dioxygenase K10712|1|6e-137|491|mmu:211488|cysteamine dioxygenase [EC:1.13.11.19] GO:0043231//intracellular membrane-bounded organelle "GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0043169//cation binding" GO:0044710 gi|225703118|ref|NP_001005419.2|/5.23015e-136/2-aminoethanethiol dioxygenase [Mus musculus] 230099 1959 0.15 0.07 -1.099535674 Down 0.181607056 Car9 carbonic anhydrase 9 K01672|1|0.0|753|mmu:230099|carbonic anhydrase [EC:4.2.1.1] GO:0044459;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0016836//hydro-lyase activity GO:0044765//single-organism transport;GO:0044237//cellular metabolic process gi|145046220|ref|NP_647466.2|/0/carbonic anhydrase 9 precursor [Mus musculus] 30946 4456 3.726666667 3.446666667 -0.112684003 Down 0.181560044 Abt1 activator of basal transcription 1 K14785|1|1e-120|437|mmu:30946|ESF2/ABP1 family protein GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003676//nucleic acid binding;GO:0036094//small molecule binding GO:0021515//cell differentiation in spinal cord;GO:0006366//transcription from RNA polymerase II promoter gi|2065210|emb|CAA73251.1|/1.25373e-159/Pro-Pol-dUTPase polyprotein [Mus musculus] 218214 4987 3.343333333 3.62 0.114702497 Up 0.181560044 Kdm1b lysine (K)-specific demethylase 1B K19413|1|0.0|1625|mmu:218214|lysine-specific histone demethylase 1B [EC:1.-.-.-] - - - - 276905 2249 0.723333333 0.866666667 0.260816581 Up 0.181531836 Armc7 armadillo repeat containing 7 "K08182|1|3e-37|159|cfa:483308|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 5;K02257|2|2e-19|100|smm:Smp_057930|protoheme IX farnesyltransferase [EC:2.5.1.-];K10610|3|6e-18|95.5|tsp:Tsp_02888|DNA damage-binding protein 1" - - - gi|29244300|ref|NP_808446.1|/8.88957e-107/armadillo repeat-containing protein 7 [Mus musculus] 74025 5894 0.683333333 0.82 0.263034406 Up 0.181531836 Nphp3 nephronophthisis 3 (adolescent) K19360|1|0.0|837|mmu:74025|nephrocystin-3 GO:0005929//cilium;GO:0005929//cilium GO:0005488//binding;GO:0005488//binding GO:0007369//gastrulation;GO:0045596//negative regulation of cell differentiation;GO:0001822//kidney development;GO:0003230//cardiac atrium development;GO:0022603//regulation of anatomical structure morphogenesis;GO:0030178//negative regulation of Wnt signaling pathway;GO:0071907//determination of digestive tract left/right asymmetry;GO:0003143//embryonic heart tube morphogenesis;GO:2000050//regulation of non-canonical Wnt signaling pathway;GO:0007601//visual perception;GO:0030323//respiratory tube development;GO:0044238//primary metabolic process;GO:0048858//cell projection morphogenesis;GO:0001889//liver development;GO:0003351//epithelial cilium movement;GO:0007369//gastrulation;GO:0045596//negative regulation of cell differentiation;GO:0001822//kidney development;GO:0003230//cardiac atrium development;GO:0022603//regulation of anatomical structure morphogenesis;GO:0030178//negative regulation of Wnt signaling pathway;GO:0071907//determination of digestive tract left/right asymmetry;GO:0003143//embryonic heart tube morphogenesis;GO:2000050//regulation of non-canonical Wnt signaling pathway;GO:0007601//visual perception;GO:0030323//respiratory tube development;GO:0044238//primary metabolic process;GO:0048858//cell projection morphogenesis;GO:0001889//liver development;GO:0003351//epithelial cilium movement gi|159131889|ref|NP_082997.3|/0/nephrocystin-3 isoform a [Mus musculus] 73016 2135 0.716666667 0.86 0.263034406 Up 0.181531836 Kremen2 kringle containing transmembrane protein 2 K01343|1|4e-15|85.9|bfo:BRAFLDRAFT_86444|tissue plasminogen activator [EC:3.4.21.68];K01315|2|2e-14|83.6|cin:100182351|plasminogen [EC:3.4.21.7] GO:0031224//intrinsic component of membrane - GO:0007166//cell surface receptor signaling pathway "gi|148690320|gb|EDL22267.1|/0/kringle containing transmembrane protein 2, isoform CRA_a, partial [Mus musculus]" 244198 1969 1.523333333 1.71 0.166764661 Up 0.181447215 Olfml1 olfactomedin-like 1 K19909|1|0.0|367|ngi:103748885|synaptotagmin-9;K04593|5|1e-23|97.8|cmk:103174714|latrophilin 2 - - - gi|589958475|ref|XP_006991832.1|/0/PREDICTED: olfactomedin-like protein 1 [Peromyscus maniculatus bairdii] 29808 13316.67 1.503333333 1.69 0.168858314 Up 0.181447215 Mga MAX gene associated K10180|1|2e-63|249|mdo:100012788|T-box protein 6 - - - gi|256017167|ref|NP_001157746.1|/0/MAX gene-associated protein isoform 2 [Mus musculus] 22099 3040 11.88333333 11.32666667 -0.069216224 Down 0.181437813 Tsn translin - GO:0043231//intracellular membrane-bounded organelle GO:0043566//structure-specific DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0004518//nuclease activity GO:0006259//DNA metabolic process "gi|21730459|pdb|1KEY|A/9.05039e-113/Chain A, Crystal Structure Of Mouse TestisBRAIN RNA-Binding Protein (Tb-Rbp)" 14579 2257 1.64 1.836666667 0.163394003 Up 0.181409605 Gem GTP binding protein (gene overexpressed in skeletal muscle) K07846|1|1e-158|563|mmu:14579|GTP binding protein overexpressed in skeletal muscle GO:0043231//intracellular membrane-bounded organelle;GO:0044459 GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0046872//metal ion binding GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process "gi|148673692|gb|EDL05639.1|/9.09645e-160/GTP binding protein (gene overexpressed in skeletal muscle), isoform CRA_a, partial [Mus musculus]" 211577 2006 1.88 1.683333333 -0.159411775 Down 0.181409605 Mrgprf "MAS-related GPR, member F" K08394|1|0.0|671|mmu:211577|Mas-related G protein-coupled receptor member F GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway "gi|148686343|gb|EDL18290.1|/0/MAS-related GPR, member F, isoform CRA_a, partial [Mus musculus]" 224814 4872 1.706666667 1.903333333 0.157346935 Up 0.181409605 Abcc10 "ATP-binding cassette, sub-family C (CFTR/MRP), member 10" "K05674|1|0.0|2412|mmu:224814|ATP-binding cassette, subfamily C (CFTR/MRP), member 10" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0015405;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763 gi|21553091|ref|NP_660122.1|/0/multidrug resistance-associated protein 7 isoform mrp7A [Mus musculus] 239530 2141 0.553333333 0.43 -0.363812176 Down 0.181381398 Gpr20 G protein-coupled receptor 20 K04317|1|0.0|671|mmu:239530|G protein-coupled receptor 20 GO:0016021//integral component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|27734082|ref|NP_775541.1|/0/G-protein coupled receptor 20 [Mus musculus] 57436 1773 141.5833333 146.9666667 0.05383753 Up 0.181353191 Gabarapl1 gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1 K08341|1|3e-63|245|lcm:102356442|GABA(A) receptor-associated protein GO:0005773//vacuole;GO:0030425//dendrite;GO:0012506//vesicle membrane;GO:0032589//neuron projection membrane;GO:0015630//microtubule cytoskeleton GO:0015631//tubulin binding;GO:0005102//receptor binding GO:0044248 gi|744582851|ref|XP_010984496.1|/2.15131e-65/PREDICTED: gamma-aminobutyric acid receptor-associated protein-like 1 [Camelus dromedarius] 22143 1747 142.4866667 147.8833333 0.053632544 Up 0.181353191 Tuba1b "tubulin, alpha 1B" K07374|1|0.0|853|xtr:100038108|tubulin alpha GO:0005874//microtubule GO:0005198//structural molecule activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0007010//cytoskeleton organization;GO:0006458//'de novo' protein folding;GO:0044765//single-organism transport;GO:0043623//cellular protein complex assembly;GO:0009154//purine ribonucleotide catabolic process;GO:0070670//response to interleukin-4 gi|34740335|ref|NP_035784.1|/0/tubulin alpha-1B chain [Mus musculus] 17068 694 0.153333333 0.076666667 -1 Down 0.181277972 Ly6d "lymphocyte antigen 6 complex, locus D" K06846|1|1e-50|201|mmu:17068|lymphocyte antigen 6 complex locus protein D/E/G6/H GO:0044464;GO:0016020//membrane - - "gi|148697498|gb|EDL29445.1|/5.57973e-51/lymphocyte antigen 6 complex, locus D [Mus musculus]" 67121 4652 0.07 0.146666667 1.067114196 Up 0.181277972 Mastl microtubule associated serine/threonine kinase-like K16309|1|0.0|1669|mmu:67121|serine/threonine-protein kinase greatwall [EC:2.7.11.1] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0032155 GO:0032550;GO:0004672//protein kinase activity GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0044772//mitotic cell cycle phase transition;GO:0000087//mitotic M phase;GO:0006464//cellular protein modification process gi|254540066|ref|NP_080255.3|/0/serine/threonine-protein kinase greatwall [Mus musculus] 12672 2768 0.076666667 0.153333333 1 Up 0.181277972 Chrm4 "cholinergic receptor, muscarinic 4" K04132|1|0.0|838|mmu:12672|muscarinic acetylcholine receptor M4 GO:0016021//integral component of membrane;GO:0005622//intracellular;GO:0044297//cell body;GO:0033267;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0005886//plasma membrane GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0008227//G-protein coupled amine receptor activity "GO:0014055//acetylcholine secretion, neurotransmission;GO:0042221//response to chemical;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0040011//locomotion" gi|755498620|ref|XP_011237573.1|/0/PREDICTED: muscarinic acetylcholine receptor M4 isoform X1 [Mus musculus] 100039795 8260 0.146666667 0.07 -1.067114196 Down 0.181277972 Ildr2 immunoglobulin-like domain containing receptor 2 - - - - gi|257153319|ref|NP_001158000.1|/0/immunoglobulin-like domain-containing receptor 2 precursor [Mus musculus] 66311 1527 0.07 0.146666667 1.067114196 Up 0.181277972 Cenpw centromere protein W - GO:0000776//kinetochore;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0034508//centromere complex assembly;GO:0000087//mitotic M phase gi|157909786|ref|NP_001103217.1|/1.15056e-40/centromere protein W [Mus musculus] 94071 2160 0.153333333 0.073333333 -1.064130337 Down 0.181277972 Clec2h "C-type lectin domain family 2, member h" K10071|1|3e-118|428|mmu:94071|C-type lectin domain family 2 member B;K10072|3|5e-68|261|cge:100769442|C-type lectin domain family 2 member D GO:0016021//integral component of membrane GO:0005102//receptor binding GO:0006952//defense response;GO:0007154//cell communication gi|83745110|ref|NP_444395.2|/2.37288e-117/C-type lectin domain family 2 member H [Mus musculus] 68308 1293 0.153333333 0.073333333 -1.064130337 Down 0.181277972 4933406F09Rik RIKEN cDNA 4933406F09 gene - - - - - 216984 3529 0.4 0.293333333 -0.447458977 Down 0.181240363 Evi2b ecotropic viral integration site 2b K16854|1|0.0|690|mmu:216984|ecotropic viral integration site 2B protein GO:0044424;GO:0016021//integral component of membrane - - gi|22122501|ref|NP_666135.1|/0/protein EVI2B precursor [Mus musculus] 66847 696 22.98333333 22.08 -0.057847879 Down 0.181221558 Hint3 histidine triad nucleotide binding protein 3 K10863|1|9e-13|75.9|clv:102086630|aprataxin [EC:3.-.-.-] GO:0031981//nuclear lumen GO:0036094//small molecule binding;GO:0003824//catalytic activity - gi|13385270|ref|NP_080074.1|/2.3924e-94/histidine triad nucleotide-binding protein 3 [Mus musculus] 66467 1191 21.78 22.67666667 0.058204634 Up 0.181221558 Gtf2h5 "general transcription factor IIH, polypeptide 5" K10845|1|2e-36|155|chx:102180044|TFIIH basal transcription factor complex TTD-A subunit GO:0043231//intracellular membrane-bounded organelle - "GO:0006281//DNA repair;GO:0006351//transcription, DNA-templated" gi|537234962|gb|ERE85013.1|/9.23862e-37/general transcription factor IIH subunit 5-like protein [Cricetulus griseus] 109161 2952 7.2 7.62 0.081794091 Up 0.181155741 Ube2q2 ubiquitin-conjugating enzyme E2Q family member 2 K10582|1|0.0|685|mmu:109161|ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23] - - - - 83410 3764 8.193333333 7.773333333 -0.075917127 Down 0.181155741 Cstf2t "cleavage stimulation factor, 3' pre-RNA subunit 2, tau" K14407|1|0.0|714|mmu:83410|cleavage stimulation factor subunit 2 - - - - 22417 3823 3.003333333 3.253333333 0.115354042 Up 0.181127534 Wnt4 "wingless-type MMTV integration site family, member 4" "K00408|1|0.0|699|mmu:22417|wingless-type MMTV integration site family, member 4" - - - gi|6678595|ref|NP_033549.1|/0/protein Wnt-4 precursor [Mus musculus] 67009 2255.3 2.746666667 2.993333333 0.124071108 Up 0.181127534 Ttc23 tetratricopeptide repeat domain 23 - - - - gi|31981132|ref|NP_080181.2|/0/tetratricopeptide repeat protein 23 isoform 1 [Mus musculus] 403183 3181 2.82 3.073333333 0.124109087 Up 0.181127534 Mettl21e methyltransferase like 21E K02357|1|1e-18|98.6|pale:102895576|elongation factor Ts - GO:0016741 GO:0008152//metabolic process gi|46402315|ref|NP_997164.1|/5.0261e-138/protein-lysine methyltransferase METTL21E [Mus musculus] 278279 5701 0.676666667 0.546666667 -0.307783913 Down 0.181042912 Tmtc2 transmembrane and tetratricopeptide repeat containing 2 K09667|1|2e-23|115|cel:CELE_K04G7.3|protein O-GlcNAc transferase [EC:2.4.1.255] GO:0031224//intrinsic component of membrane - - gi|50962841|ref|NP_796342.2|/0/transmembrane and TPR repeat-containing protein 2 precursor [Mus musculus] 12182 2336 0.526666667 0.653333333 0.310929096 Up 0.181042912 Bst1 bone marrow stromal cell antigen 1 K18152|1|3e-155|551|mmu:12182|ADP-ribosyl cyclase 2 [EC:3.2.2.6 2.4.99.20] GO:0031224//intrinsic component of membrane "GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0036094//small molecule binding" - gi|134288869|ref|NP_033893.2|/2.67422e-154/ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 precursor [Mus musculus] 236366 2470 0.66 0.533333333 -0.307428525 Down 0.181042912 5730507C01Rik RIKEN cDNA 5730507C01 gene K09228|1|9e-165|540|mmu:628709|KRAB domain-containing zinc finger protein - - - gi|318067916|ref|NP_001188259.1|/0/zinc finger protein-like isoform 1 [Mus musculus] 12286 7788 0.666666667 0.536666667 -0.312939312 Down 0.181042912 Cacna1a "calcium channel, voltage-dependent, P/Q type, alpha 1A subunit" K04344|1|0.0|3910|mmu:12286|voltage-dependent calcium channel P/Q type alpha-1A GO:0043005//neuron projection;GO:0034704//calcium channel complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043025//neuronal cell body GO:0005245//voltage-gated calcium channel activity;GO:0000149//SNARE binding;GO:0003676//nucleic acid binding;GO:0043169//cation binding "GO:0050804//modulation of synaptic transmission;GO:0033555//multicellular organismal response to stress;GO:0031327;GO:0019318//hexose metabolic process;GO:0014055//acetylcholine secretion, neurotransmission;GO:0016358//dendrite development;GO:0042391//regulation of membrane potential;GO:0072657//protein localization to membrane;GO:0007600//sensory perception;GO:0050881//musculoskeletal movement;GO:0007409//axonogenesis;GO:0017156//calcium ion regulated exocytosis;GO:0040007//growth;GO:0030320//cellular monovalent inorganic anion homeostasis;GO:0007270//neuron-neuron synaptic transmission;GO:0008344//adult locomotory behavior;GO:0015812//gamma-aminobutyric acid transport;GO:0021533//cell differentiation in hindbrain;GO:0021695//cerebellar cortex development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0021515//cell differentiation in spinal cord;GO:0070588//calcium ion transmembrane transport;GO:0043066//negative regulation of apoptotic process;GO:0050905//neuromuscular process;GO:0006575//cellular modified amino acid metabolic process;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0021548//pons development" gi|74181109|dbj|BAE27823.1|/0/unnamed protein product [Mus musculus] 18633 1345.66 21.05 21.93666667 0.059524088 Up 0.180995901 Pex16 peroxisomal biogenesis factor 16 K13335|1|4e-141|503|mmu:18633|peroxin-16 GO:0031231//intrinsic component of peroxisomal membrane;GO:0031231//intrinsic component of peroxisomal membrane GO:0005515//protein binding;GO:0005515//protein binding GO:0006625//protein targeting to peroxisome;GO:0022406//membrane docking;GO:0006625//protein targeting to peroxisome;GO:0022406//membrane docking gi|14789912|gb|AAH10822.1|/2.35198e-160/Peroxisomal biogenesis factor 16 [Mus musculus] 68185 834 11.43666667 11.98333333 0.067362645 Up 0.180948889 Coa4 cytochrome c oxidase assembly factor 4 K18177|1|1e-34|148|mmu:68185|cytochrome c oxidase assembly factor 4 GO:0043231//intracellular membrane-bounded organelle - - "gi|34304060|ref|NP_899093.1|/1.17038e-33/cytochrome c oxidase assembly factor 4 homolog, mitochondrial [Mus musculus]" 20617 1304 0.316666667 0.43 0.441371647 Up 0.180704427 Snca "synuclein, alpha" K04528|1|4e-53|211|mmu:20617|alpha-synuclein GO:0033267;GO:0030529//intracellular ribonucleoprotein complex;GO:0030136//clathrin-coated vesicle;GO:0030667//secretory granule membrane;GO:0005783//endoplasmic reticulum;GO:0005578//proteinaceous extracellular matrix;GO:0031965//nuclear membrane;GO:0005856//cytoskeleton;GO:0033267;GO:0030529//intracellular ribonucleoprotein complex;GO:0030136//clathrin-coated vesicle;GO:0030667//secretory granule membrane;GO:0005783//endoplasmic reticulum;GO:0005578//proteinaceous extracellular matrix;GO:0031965//nuclear membrane;GO:0005856//cytoskeleton GO:0008289//lipid binding;GO:0003824//catalytic activity;GO:0050542;GO:0031072//heat shock protein binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0015631//tubulin binding;GO:0019899//enzyme binding;GO:0005506//iron ion binding;GO:0004859//phospholipase inhibitor activity;GO:0008289//lipid binding;GO:0003824//catalytic activity;GO:0050542;GO:0031072//heat shock protein binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0015631//tubulin binding;GO:0019899//enzyme binding;GO:0005506//iron ion binding;GO:0004859//phospholipase inhibitor activity "GO:0007626//locomotory behavior;GO:0001963//synaptic transmission, dopaminergic;GO:0034097//response to cytokine;GO:0051899//membrane depolarization;GO:0002237//response to molecule of bacterial origin;GO:0006979//response to oxidative stress;GO:0044767//single-organism developmental process;GO:0030534//adult behavior;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0001881//receptor recycling;GO:0071363//cellular response to growth factor stimulus;GO:0032768;GO:0002694;GO:0042773//ATP synthesis coupled electron transport;GO:0042053//regulation of dopamine metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0045860//positive regulation of protein kinase activity;GO:0010676;GO:0031111//negative regulation of microtubule polymerization or depolymerization;GO:0016573//histone acetylation;GO:0046688//response to copper ion;GO:0007005//mitochondrion organization;GO:0010039//response to iron ion;GO:0048168//regulation of neuronal synaptic plasticity;GO:0042116//macrophage activation;GO:0060191;GO:0043271//negative regulation of ion transport;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0040011//locomotion;GO:0019217//regulation of fatty acid metabolic process;GO:0031647//regulation of protein stability;GO:0030198//extracellular matrix organization;GO:0006898//receptor-mediated endocytosis;GO:0006887//exocytosis;GO:0032409;GO:0007269//neurotransmitter secretion;GO:0051620;GO:0071870//cellular response to catecholamine stimulus;GO:0007626//locomotory behavior;GO:0001963//synaptic transmission, dopaminergic;GO:0034097//response to cytokine;GO:0051899//membrane depolarization;GO:0002237//response to molecule of bacterial origin;GO:0006979//response to oxidative stress;GO:0044767//single-organism developmental process;GO:0030534//adult behavior;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0001881//receptor recycling;GO:0071363//cellular response to growth factor stimulus;GO:0032768;GO:0002694;GO:0042773//ATP synthesis coupled electron transport;GO:0042053//regulation of dopamine metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0045860//positive regulation of protein kinase activity;GO:0010676;GO:0031111//negative regulation of microtubule polymerization or depolymerization;GO:0016573//histone acetylation;GO:0046688//response to copper ion;GO:0007005//mitochondrion organization;GO:0010039//response to iron ion;GO:0048168//regulation of neuronal synaptic plasticity;GO:0042116//macrophage activation;GO:0060191;GO:0043271//negative regulation of ion transport;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0040011//locomotion;GO:0019217//regulation of fatty acid metabolic process;GO:0031647//regulation of protein stability;GO:0030198//extracellular matrix organization;GO:0006898//receptor-mediated endocytosis;GO:0006887//exocytosis;GO:0032409;GO:0007269//neurotransmitter secretion;GO:0051620;GO:0071870//cellular response to catecholamine stimulus" "gi|148666340|gb|EDK98756.1|/9.72024e-58/synuclein, alpha, isoform CRA_b, partial [Mus musculus]" 73284 2721 0.306666667 0.416666667 0.442222329 Up 0.180704427 Ddit4l DNA-damage-inducible transcript 4-like K08270|1|9e-29|131|cmk:103181311|DNA-damage-inducible transcript 4 - - - - 19737 4083.12 136.9333333 132.5566667 -0.046864452 Down 0.180695024 Rgs5 regulator of G-protein signaling 5 K16449|1|1e-77|294|mmu:19737|regulator of G-protein signaling - - - - 16527 3810 139.13 134.7733333 -0.045898467 Down 0.180676219 Kcnk3 "potassium channel, subfamily K, member 3" K04914|1|0.0|729|mmu:16527|potassium channel subfamily K member 3 GO:0031224//intrinsic component of membrane GO:0005249//voltage-gated potassium channel activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity GO:0001666//response to hypoxia;GO:0007417//central nervous system development;GO:0044767//single-organism developmental process;GO:0010043//response to zinc ion;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0051480//regulation of cytosolic calcium ion concentration gi|33859576|ref|NP_034738.1|/0/potassium channel subfamily K member 3 [Mus musculus] 104570 5111 2.466666667 2.696666667 0.128614432 Up 0.180657415 Smek2 "SMEK homolog 2, suppressor of mek1 (Dictyostelium)" K17491|1|0.0|1550|mmu:104570|protein phosphatase 4 regulatory subunit 3 - - - - 69707 4027 2.473333333 2.703333333 0.128282728 Up 0.180657415 Iqcg IQ motif containing G K10397|1|4e-68|263|cin:100184728|kinesin family member 6/9;K19514|2|2e-07|61.2|myb:102240245|renin receptor - - - - 71862 2020 2.58 2.35 -0.134710309 Down 0.180657415 Gpr160 G protein-coupled receptor 160 K08438|1|7e-172|606|mmu:71862|G protein-coupled receptor 160 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway gi|197304666|ref|NP_001127857.1|/5.48054e-171/probable G-protein coupled receptor 160 [Mus musculus] 208836 4621 2.36 2.59 0.134165238 Up 0.180657415 Fanci "Fanconi anemia, complementation group I" K10895|1|0.0|2404|mmu:208836|fanconi anemia group I protein - - - gi|126722700|ref|NP_666058.2|/0/Fanconi anemia group I protein homolog [Mus musculus] 14049 2357.88 2.44 2.67 0.129958594 Up 0.180657415 Eya2 EYA transcriptional coactivator and phosphatase 2 K17620|1|0.0|1021|mmu:14049|eyes absent homolog 2 [EC:3.1.3.48] - - - - 18247 1861 110.29 114.52 0.054297588 Up 0.180582196 Oaz2 ornithine decarboxylase antizyme 2 K16613|1|2e-78|296|pale:102882667|ornithine decarboxylase antizyme 2 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0004857//enzyme inhibitor activity;GO:0005488//binding;GO:0004857//enzyme inhibitor activity GO:0006576//cellular biogenic amine metabolic process;GO:0006520//cellular amino acid metabolic process;GO:0044092//negative regulation of molecular function;GO:0006576//cellular biogenic amine metabolic process;GO:0006520//cellular amino acid metabolic process;GO:0044092//negative regulation of molecular function "gi|119598096|gb|EAW77690.1|/6.62287e-89/ornithine decarboxylase antizyme 2, isoform CRA_a, partial [Homo sapiens]" 26556 4508.52 5.953333333 5.606666667 -0.086554375 Down 0.180544586 Homer1 homer scaffolding protein 1 K15010|1|0.0|688|mmu:26556|homer - - - - 213109 7561 5.793333333 5.443333333 -0.089903291 Down 0.180544586 Phf3 PHD finger protein 3 K17596|1|1e-72|279|pss:102451173|SPOC domain-containing protein 1 - GO:0043169//cation binding - gi|124487309|ref|NP_001074549.1|/0/PHD finger protein 3 [Mus musculus] 71665 2523 11.23333333 11.77333333 0.067736752 Up 0.180516379 Fuca1 "fucosidase, alpha-L- 1, tissue" K01206|1|0.0|944|mmu:71665|alpha-L-fucosidase [EC:3.2.1.51] GO:0000323//lytic vacuole GO:0015928//fucosidase activity;GO:0005488//binding GO:0016137//glycoside metabolic process;GO:0006026;GO:0019318//hexose metabolic process gi|169808427|ref|NP_077205.3|/0/tissue alpha-L-fucosidase precursor [Mus musculus] 225027 2485.59 10.91666667 11.45333333 0.06923513 Up 0.180516379 Srsf7 serine/arginine-rich splicing factor 7 "K12896|1|1e-54|217|tup:102481554|splicing factor, arginine/serine-rich 7" - - - "gi|148706565|gb|EDL38512.1|/2.51216e-56/mCG17902, isoform CRA_k, partial [Mus musculus]" 330660 3459 0.583333333 0.716666667 0.296981738 Up 0.180431757 Btbd16 BTB (POZ) domain containing 16 K10487|1|0.0|1004|mmu:330660|BTB/POZ domain-containing protein 16 - - - - 12768 2831 0.683333333 0.553333333 -0.304440668 Down 0.180431757 Ccr1 chemokine (C-C motif) receptor 1 K04176|1|2e-168|595|mmu:12768|C-C chemokine receptor type 1 GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0044297//cell body GO:0019957//C-C chemokine binding;GO:0004629//phospholipase C activity;GO:0004950//chemokine receptor activity GO:0010467//gene expression;GO:0001660//fever generation;GO:0022037//metencephalon development;GO:0031348//negative regulation of defense response;GO:0043410//positive regulation of MAPK cascade;GO:0019221//cytokine-mediated signaling pathway;GO:0022610;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0002237//response to molecule of bacterial origin;GO:0007186//G-protein coupled receptor signaling pathway;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0016192//vesicle-mediated transport;GO:0006816//calcium ion transport;GO:0030279//negative regulation of ossification;GO:0051480//regulation of cytosolic calcium ion concentration gi|157012007|ref|NP_034042.3|/2.02289e-167/C-C chemokine receptor type 1 [Mus musculus] 72931 772.05 125.1133333 129.18 0.04614718 Up 0.180431757 Swi5 SWI5 recombination repair homolog (yeast) - GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0000725//recombinational repair;GO:0000725//recombinational repair;GO:0000725//recombinational repair gi|594346510|ref|NP_001277481.1|/5.60107e-56/DNA repair protein SWI5 homolog isoform a [Mus musculus] 72397 3313 0.703333333 0.57 -0.303246674 Down 0.180431757 Rbm12b1 RNA binding motif protein 12 B1 K14947|1|1e-16|91.7|lgi:LOTGIDRAFT_91728|epithelial splicing regulatory protein 1/2 - - - - 216549 3996.03 4.443333333 4.746666667 0.095272366 Up 0.180337734 Aftph aftiphilin - GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0030130//clathrin coat of trans-Golgi network vesicle GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0045184//establishment of protein localization;GO:0045184//establishment of protein localization;GO:0045184//establishment of protein localization "gi|148675891|gb|EDL07838.1|/0/aftiphilin, isoform CRA_a, partial [Mus musculus]" 55943 4123 4.62 4.316666667 -0.09797516 Down 0.180337734 Stx8 syntaxin 8 K08501|1|9e-100|368|mmu:55943|syntaxin 8 GO:0043234//protein complex;GO:0005770//late endosome;GO:0031224//intrinsic component of membrane GO:0044389//ubiquitin-like protein ligase binding GO:0007041//lysosomal transport;GO:0016192//vesicle-mediated transport "gi|149052985|gb|EDM04802.1|/4.54799e-102/syntaxin 8, isoform CRA_b [Rattus norvegicus]" 13636 1483 21.18666667 20.33666667 -0.059073394 Down 0.180300124 Efna1 ephrin A1 K05462|1|4e-109|397|mmu:13636|ephrin-A GO:0031225//anchored component of membrane;GO:0031225//anchored component of membrane GO:0005102//receptor binding;GO:0005102//receptor binding GO:0001934//positive regulation of protein phosphorylation;GO:0001525//angiogenesis;GO:0010594//regulation of endothelial cell migration;GO:0006366//transcription from RNA polymerase II promoter;GO:0003176//aortic valve development;GO:0001837//epithelial to mesenchymal transition;GO:0007409//axonogenesis;GO:0003188//heart valve formation;GO:0030155//regulation of cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003174//mitral valve development;GO:0031345//negative regulation of cell projection organization;GO:0001934//positive regulation of protein phosphorylation;GO:0001525//angiogenesis;GO:0010594//regulation of endothelial cell migration;GO:0006366//transcription from RNA polymerase II promoter;GO:0003176//aortic valve development;GO:0001837//epithelial to mesenchymal transition;GO:0007409//axonogenesis;GO:0003188//heart valve formation;GO:0030155//regulation of cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003174//mitral valve development;GO:0031345//negative regulation of cell projection organization gi|672043177|ref|XP_008759449.1|/1.78618e-123/PREDICTED: ephrin-A1 isoform X1 [Rattus norvegicus] 53331 2500 18.93 19.78 0.063368015 Up 0.180300124 Stx7 syntaxin 7 K08488|1|2e-117|426|mmu:53331|syntaxin 7 - - - gi|20139979|sp|O70439.3|STX7_MOUSE/1.83523e-116/RecName: Full=Syntaxin-7 207592 6988 19.11333333 19.96666667 0.063014098 Up 0.180300124 Tbc1d16 "TBC1 domain family, member 16" K20168|1|1e-52|212|phu:Phum_PHUM612120|TBC1 domain family member 15 - - - "gi|148702739|gb|EDL34686.1|/0/TBC1 domain family, member 16, isoform CRA_b, partial [Mus musculus]" 244923 6260 19.17333333 20.02666667 0.062821137 Up 0.180300124 Klhl31 kelch-like 31 K10467|1|0.0|1193|mmu:244923|kelch-like protein 31 - - "GO:0006351//transcription, DNA-templated" gi|124486714|ref|NP_766513.2|/0/kelch-like protein 31 [Mus musculus] 94249 3436 1.143333333 0.986666667 -0.212611401 Down 0.180281319 Slc24a3 "solute carrier family 24 (sodium/potassium/calcium exchanger), member 3" "K13751|1|0.0|1104|rno:85267|solute carrier family 24 (sodium/potassium/calcium exchanger), member 3" - - - - 107272 2172 1.016666667 1.176666667 0.210858941 Up 0.180281319 Psat1 phosphoserine aminotransferase 1 K00831|1|0.0|677|mmu:107272|phosphoserine aminotransferase [EC:2.6.1.52] - GO:0043168//anion binding;GO:0008483//transaminase activity;GO:0043168//anion binding;GO:0008483//transaminase activity GO:0006563//L-serine metabolic process;GO:0006563//L-serine metabolic process gi|329299029|ref|NP_001192268.1|/0/phosphoserine aminotransferase isoform 2 [Mus musculus] 381318 2973 0.56 0.44 -0.347923303 Down 0.180271917 Nsl1 "NSL1, MIS12 kinetochore complex component" K11545|1|1e-145|520|mmu:381318|kinetochore-associated protein NSL1 "GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region" - GO:0000087//mitotic M phase "gi|148681059|gb|EDL13006.1|/3.93758e-145/RIKEN cDNA 4833432M17, isoform CRA_b, partial [Mus musculus]" 12662 4867 1.36 1.543333333 0.182443041 Up 0.180234307 Chm choroidermia (RAB escort protein 1) K17255|1|3e-29|134|obi:106870635|Rab GDP dissociation inhibitor GO:0043234//protein complex GO:0008047//enzyme activator activity;GO:0017016//Ras GTPase binding;GO:0004661//protein geranylgeranyltransferase activity GO:0001944//vasculature development;GO:0015031//protein transport gi|110681714|ref|NP_061288.2|/0/rab proteins geranylgeranyltransferase component A 1 [Mus musculus] 448987 4639 1.593333333 1.41 -0.176352955 Down 0.180234307 Fbxl7 F-box and leucine-rich repeat protein 7 K10273|1|0.0|959|mmu:448987|F-box and leucine-rich repeat protein 7 GO:0005815//microtubule organizing center;GO:0031461//cullin-RING ubiquitin ligase complex GO:0005488//binding;GO:0019787//ubiquitin-like protein transferase activity GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation;GO:0044772//mitotic cell cycle phase transition;GO:0000087//mitotic M phase gi|37360118|dbj|BAC98037.1|/0/mKIAA0840 protein [Mus musculus] 102639598 4280.33 1.356666667 1.533333333 0.176605067 Up 0.180234307 Gm14296 predicted gene 14296 K09228|1|2e-164|583|mmu:665211|KRAB domain-containing zinc finger protein - - - gi|755473579|ref|XP_006543785.2|/0/PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 431-like isoform X1 [Mus musculus] 77035 2445 1.386666667 1.566666667 0.176077228 Up 0.180234307 Kdm8 lysine (K)-specific demethylase 8 K10277|1|0.0|793|mmu:77035|lysine-specific demethylase 8 [EC:1.14.11.27] GO:0043231//intracellular membrane-bounded organelle "GO:0043169//cation binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" "GO:0044772//mitotic cell cycle phase transition;GO:0070076//histone lysine demethylation;GO:0006351//transcription, DNA-templated" gi|21313318|ref|NP_084118.1|/0/lysine-specific demethylase 8 [Mus musculus] 268564 4001 1.506666667 1.326666667 -0.183554342 Down 0.180234307 Zbtb1 zinc finger and BTB domain containing 1 K10488|1|0.0|1414|mmu:268564|zinc finger and BTB domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0030217//T cell differentiation;GO:0006351//transcription, DNA-templated" "gi|148704515|gb|EDL36462.1|/0/zinc finger and BTB domain containing 1, partial [Mus musculus]" 382066 3408 0.426666667 0.316666667 -0.430144392 Down 0.180224905 Prdm10 PR domain containing 10 K09228|1|7e-37|159|gja:107124153|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|124249099|ref|NP_001074286.1|/0/PR domain zinc finger protein 10 precursor [Mus musculus] 68352 966 0.32 0.43 0.426264755 Up 0.180224905 Aspdh aspartate dehydrogenase domain containing K15235|1|2e-138|493|mcc:719609|josephin [EC:3.4.19.12];K16360|3|6e-52|206|fch:102051070|netrin-G3 ligand - "GO:0016638//oxidoreductase activity, acting on the CH-NH2 group of donors;GO:0000166//nucleotide binding" GO:0006739//NADP metabolic process;GO:0019359//nicotinamide nucleotide biosynthetic process "gi|148669279|gb|EDL01226.1|/1.28097e-165/mCG8752, isoform CRA_b, partial [Mus musculus]" 71131 3637 1.22 1.393333333 0.191659294 Up 0.180168491 Zfp689 zinc finger protein 689 K09228|1|0.0|999|mmu:71131|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0007519//skeletal muscle tissue development;GO:0006351//transcription, DNA-templated" gi|169808405|ref|NP_780372.2|/0/zinc finger protein 689 [Mus musculus] 12785 2165.48 113.7633333 117.5933333 0.04777063 Up 0.180168491 Cnbp cellular nucleic acid binding protein K09250|1|2e-99|365|pale:102878136|cellular nucleic acid-binding protein GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0043566//structure-specific DNA binding;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0043566//structure-specific DNA binding;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0043566//structure-specific DNA binding GO:0008283//cell proliferation;GO:0008203//cholesterol metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0008203//cholesterol metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0008203//cholesterol metabolic process;GO:0006366//transcription from RNA polymerase II promoter "gi|148666815|gb|EDK99231.1|/4.61471e-113/cellular nucleic acid binding protein, isoform CRA_d, partial [Mus musculus]" 69631 1122 7.5 7.09 -0.081104968 Down 0.180168491 Plet1os "placenta expressed transcript 1, opposite strand" - - - - - 21386 4679.92 7.7 7.29 -0.078939631 Down 0.180168491 Tbx3 T-box 3 K10177|1|0.0|1065|mmu:21386|T-box protein 3 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0003677//DNA binding "GO:0030326//embryonic limb morphogenesis;GO:0060592//mammary gland formation;GO:0046545//development of primary female sexual characteristics;GO:0045445//myoblast differentiation;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0007498//mesoderm development;GO:0003166//bundle of His development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0046546//development of primary male sexual characteristics;GO:0043009//chordate embryonic development;GO:0051726//regulation of cell cycle;GO:0030900//forebrain development;GO:0006351//transcription, DNA-templated;GO:0007569//cell aging;GO:0060921//sinoatrial node cell differentiation;GO:0032274;GO:0003281//ventricular septum development;GO:0000578//embryonic axis specification;GO:0003143//embryonic heart tube morphogenesis;GO:0030855//epithelial cell differentiation;GO:0003002//regionalization;GO:0001944//vasculature development;GO:0030326//embryonic limb morphogenesis;GO:0060592//mammary gland formation;GO:0046545//development of primary female sexual characteristics;GO:0045445//myoblast differentiation;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0007498//mesoderm development;GO:0003166//bundle of His development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0046546//development of primary male sexual characteristics;GO:0043009//chordate embryonic development;GO:0051726//regulation of cell cycle;GO:0030900//forebrain development;GO:0006351//transcription, DNA-templated;GO:0007569//cell aging;GO:0060921//sinoatrial node cell differentiation;GO:0032274;GO:0003281//ventricular septum development;GO:0000578//embryonic axis specification;GO:0003143//embryonic heart tube morphogenesis;GO:0030855//epithelial cell differentiation;GO:0003002//regionalization;GO:0001944//vasculature development" gi|37622347|ref|NP_035665.2|/0/T-box transcription factor TBX3 isoform 1 [Mus musculus] 13449 1717 1.21 1.376666667 0.186172233 Up 0.180168491 Dok2 docking protein 2 K20234|1|0.0|848|mmu:13449|docking protein 2 - "GO:0004871//signal transducer activity;GO:0008289//lipid binding;GO:0030674//protein binding, bridging;GO:0005102//receptor binding" GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007264//small GTPase mediated signal transduction gi|6753668|ref|NP_034201.1|/0/docking protein 2 [Mus musculus] 69923 2225 6.87 7.28 0.083628351 Up 0.180168491 Agk acylglycerol kinase K09881|1|0.0|811|mmu:69923|acylglycerol kinase [EC:2.7.1.94] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0001727//lipid kinase activity GO:0016310//phosphorylation;GO:0006672//ceramide metabolic process;GO:0007186//G-protein coupled receptor signaling pathway "gi|564346506|ref|XP_006236425.1|/0/PREDICTED: acylglycerol kinase, mitochondrial isoform X2 [Rattus norvegicus]" 233406 2972 1.403333333 1.23 -0.190199417 Down 0.180168491 Prc1 protein regulator of cytokinesis 1 K16732|1|0.0|1064|mmu:233406|protein regulator of cytokinesis 1 GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0031981//nuclear lumen;GO:0015630//microtubule cytoskeleton GO:0015631//tubulin binding;GO:0019900//kinase binding;GO:0015631//tubulin binding;GO:0019900//kinase binding;GO:0015631//tubulin binding;GO:0019900//kinase binding GO:0044763;GO:0044763;GO:0044763 "gi|148675068|gb|EDL07015.1|/0/protein regulator of cytokinesis 1, isoform CRA_d, partial [Mus musculus]" 241547 2321 3.37 3.636666667 0.109868104 Up 0.180055662 Harbi1 harbinger transposase derived 1 K18274|1|1e-14|84.3|xtr:100492097|uromodulin GO:0043231//intracellular membrane-bounded organelle "GO:0016788//hydrolase activity, acting on ester bonds;GO:0043169//cation binding" - gi|62871735|gb|AAH94315.1|/0/Harbi1 protein [Mus musculus] 666704 2071 10.28 10.81 0.072526259 Up 0.180055662 Samd1 sterile alpha motif domain containing 1 K04431|1|3e-13|79.7|gfr:102038813|mitogen-activated protein kinase kinase 7 [EC:2.7.12.2];K11457|2|8e-08|61.6|lcm:102350230|polyhomeotic-like protein 2;K11461|5|2e-07|60.1|bom:102277147|polycomb protein SCMH1 GO:0044424 - - "gi|148678975|gb|EDL10922.1|/6.19294e-91/mCG5909, partial [Mus musculus]" 72190 5164 3.523333333 3.256666667 -0.113544909 Down 0.180055662 2510009E07Rik RIKEN cDNA 2510009E07 gene - - - - gi|49457853|ref|NP_001001881.1|/5.74549e-134/UPF0524 protein C3orf70 homolog [Mus musculus] 80911 3977 11.38 10.84666667 -0.069248807 Down 0.180055662 Acox3 "acyl-Coenzyme A oxidase 3, pristanoyl" K00232|1|0.0|1373|mmu:80911|acyl-CoA oxidase [EC:1.3.3.6] GO:0044439 GO:0003997//acyl-CoA oxidase activity;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0000166//nucleotide binding GO:0006635//fatty acid beta-oxidation "gi|148705543|gb|EDL37490.1|/0/acyl-Coenzyme A oxidase 3, pristanoyl, isoform CRA_c, partial [Mus musculus]" 58231 5189 3.636666667 3.37 -0.109868104 Down 0.180055662 Stk4 serine/threonine kinase 4 K04411|1|0.0|937|mmu:58231|serine/threonine kinase 4 GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0030295//protein kinase activator activity;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0042802//identical protein binding GO:0001525//angiogenesis;GO:0032989;GO:0035265//organ growth;GO:0007507//heart development;GO:0001892//embryonic placenta development;GO:0035162//embryonic hemopoiesis;GO:0008283//cell proliferation;GO:0009913//epidermal cell differentiation;GO:0006915//apoptotic process;GO:0030178//negative regulation of Wnt signaling pathway;GO:0012502//induction of programmed cell death;GO:0045860//positive regulation of protein kinase activity;GO:0007399//nervous system development;GO:0001838//embryonic epithelial tube formation;GO:0035556//intracellular signal transduction gi|12328814|ref|NP_067395.1|/0/serine/threonine-protein kinase 4 [Mus musculus] 23806 6435 10.72333333 10.19666667 -0.072655829 Down 0.180055662 Arih1 ariadne RBR E3 ubiquitin protein ligase 1 K11968|1|0.0|964|pale:102898538|ariadne-1 [EC:2.3.2.27] - - - - 18807 2308 20.03333333 19.19666667 -0.061546669 Down 0.180055662 Pld3 "phospholipase D family, member 3" K16860|1|0.0|941|mmu:18807|phospholipase D3/4 [EC:3.1.4.4] - - - - 56427 1882 3.433333333 3.706666667 0.110512451 Up 0.180055662 Tubd1 "tubulin, delta 1" K10390|1|0.0|924|mmu:56427|tubulin delta GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0005198//structural molecule activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0005198//structural molecule activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0005198//structural molecule activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0005198//structural molecule activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0048869//cellular developmental process;GO:0043623//cellular protein complex assembly;GO:0048232//male gamete generation;GO:0009154//purine ribonucleotide catabolic process;GO:0048869//cellular developmental process;GO:0043623//cellular protein complex assembly;GO:0048232//male gamete generation;GO:0009154//purine ribonucleotide catabolic process;GO:0048869//cellular developmental process;GO:0043623//cellular protein complex assembly;GO:0048232//male gamete generation;GO:0009154//purine ribonucleotide catabolic process;GO:0048869//cellular developmental process;GO:0043623//cellular protein complex assembly;GO:0048232//male gamete generation;GO:0009154//purine ribonucleotide catabolic process "gi|148683844|gb|EDL15791.1|/0/tubulin, delta 1, isoform CRA_c, partial [Mus musculus]" 225896 1048 105.3733333 109.0333333 0.049259446 Up 0.179999248 Ubxn1 UBX domain protein 1 K18993|1|1e-10|69.7|xtr:100125040|ubiquitin-associated and SH3 domain-containing protein [EC:3.1.3.48] GO:0043005//neuron projection;GO:0044297//cell body;GO:0005789//endoplasmic reticulum membrane GO:0031593//polyubiquitin binding;GO:0044389//ubiquitin-like protein ligase binding GO:0016567//protein ubiquitination;GO:0031330 gi|564332722|ref|XP_006231037.1|/1.21676e-127/PREDICTED: UBX domain-containing protein 1 isoform X1 [Rattus norvegicus] 72289 6982 112.7266667 116.3633333 0.045807689 Up 0.179980443 Malat1 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) "K03847|1|7e-07|45.1|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - "gi|67975423|ref|XP_668908.1|/5.13957e-16/hypothetical protein [Plasmodium berghei strain ANKA], partial [Plasmodium berghei ANKA]" 216558 2792.09 113.1333333 109.51 -0.046961447 Down 0.179952236 Ugp2 UDP-glucose pyrophosphorylase 2 K00963|1|0.0|941|mmu:216558|UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0019103//pyrimidine nucleotide binding;GO:0051748//UTP-monosaccharide-1-phosphate uridylyltransferase activity;GO:0048029//monosaccharide binding;GO:0043169//cation binding;GO:0019103//pyrimidine nucleotide binding;GO:0051748//UTP-monosaccharide-1-phosphate uridylyltransferase activity;GO:0048029//monosaccharide binding GO:0019318//hexose metabolic process;GO:0009226//nucleotide-sugar biosynthetic process;GO:0005977//glycogen metabolic process;GO:0019318//hexose metabolic process;GO:0009226//nucleotide-sugar biosynthetic process;GO:0005977//glycogen metabolic process "gi|148675899|gb|EDL07846.1|/0/UDP-glucose pyrophosphorylase 2, isoform CRA_a, partial [Mus musculus]" 233274 2204 0.073333333 0.013333333 -2.459431619 Down 0.179905224 Siglech sialic acid binding Ig-like lectin H K06473|1|9e-77|290|mmu:233274|CD33 antigen GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|755520972|ref|XP_011249160.1|/2.71454e-169/PREDICTED: sialic acid binding Ig-like lectin H isoform X3 [Mus musculus] 77011 7213 0.013333333 0.073333333 2.459431619 Up 0.179905224 Ticrr TOPBP1-interacting checkpoint and replication regulator - GO:0043231//intracellular membrane-bounded organelle - GO:0000076//DNA replication checkpoint;GO:0006270//DNA replication initiation;GO:0009314//response to radiation;GO:0033554//cellular response to stress gi|78354983|ref|NP_084111.1|/0/treslin [Mus musculus] 15467 2805 20.87 20.03666667 -0.058788081 Down 0.179830005 Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 K16194|1|0.0|1087|mmu:15467|eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1] GO:0044424 GO:0046906//tetrapyrrole binding;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0042802//identical protein binding GO:0006413//translational initiation;GO:0050896//response to stimulus;GO:0001932//regulation of protein phosphorylation;GO:0006778//porphyrin-containing compound metabolic process;GO:0042541//hemoglobin biosynthetic process;GO:0008283//cell proliferation gi|50510905|dbj|BAD32438.1|/0/mKIAA1369 protein [Mus musculus] 100041244 2092 0.33 0.44 0.415037499 Up 0.1798112 Gm3230 predicted gene 3230 K13716|1|6e-33|145|rno:498803|OTU domain-containing protein 1 [EC:3.4.19.12] - - - gi|672030347|ref|XP_008772264.1|/5.05181e-32/PREDICTED: OTU domain-containing protein 1 isoform X1 [Rattus norvegicus] 242484 2929 0.42 0.313333333 -0.422691072 Down 0.1798112 D630039A03Rik RIKEN cDNA D630039A03 gene - - - - gi|30520163|ref|NP_848842.1|/3.28137e-136/uncharacterized protein C9orf152 homolog [Mus musculus] 74341 2370 0.126666667 0.22 0.796466606 Up 0.179604348 G630025P09Rik RIKEN cDNA G630025P09 gene K04358|1|2e-126|456|cfa:607829|fibroblast growth factor;K16271|3|2e-119|383|chx:102190496|E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27] - - - gi|145966766|ref|NP_001028605.2|/0/transmembrane protein 102 [Mus musculus] 67593 2042 0.213333333 0.123333333 -0.790546634 Down 0.179604348 4930519G04Rik RIKEN cDNA 4930519G04 gene - - - - "gi|148687947|gb|EDL19894.1|/1.94633e-105/RIKEN cDNA 4930519G04, isoform CRA_b, partial [Mus musculus]" 666747 2262 0.22 0.126666667 -0.796466606 Down 0.179604348 Trim43b tripartite motif-containing 43B K12019|1|0.0|923|mmu:666747|tripartite motif-containing protein 43/48/49/64/77 GO:0044464 GO:0046914//transition metal ion binding - gi|283046820|ref|NP_001164355.1|/0/tripartite motif-containing protein 43B [Mus musculus] 66437 806.08 104.29 107.64 0.045613467 Up 0.179594945 Fis1 "fission, mitochondrial 1" K17969|1|2e-71|270|umr:103670131|mitochondrial fission 1 protein - - - - 243780 1951 0.1 0.026666667 -1.906890596 Down 0.179510324 E330009J07Rik RIKEN cDNA E330009J07 gene K14772|1|1e-118|429|xma:102225359|U3 small nucleolar RNA-associated protein 20 - - - gi|148681639|gb|EDL13586.1|/0/RIKEN cDNA E330009J07 [Mus musculus] 72027 2249 0.026666667 0.093333333 1.807354922 Up 0.179510324 Slc39a4 "solute carrier family 39 (zinc transporter), member 4" "K14710|1|0.0|1017|mmu:72027|solute carrier family 39 (zinc transporter), member 4" GO:0031224//intrinsic component of membrane;GO:0044459;GO:0005768//endosome GO:0046915//transition metal ion transmembrane transporter activity GO:0006829//zinc II ion transport;GO:0009267//cellular response to starvation;GO:0072503 gi|21312508|ref|NP_082340.1|/0/zinc transporter ZIP4 precursor [Mus musculus] 68954 611 0.456666667 0.58 0.344911413 Up 0.179482117 1500012K07Rik RIKEN cDNA 1500012K07 gene - - - - - 15413 1912 0.13 0.223333333 0.780686972 Up 0.179444507 Hoxb5 homeobox B5 K09305|1|9e-115|416|rno:497987|homeobox protein HoxA/B/C5 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0003002//regionalization;GO:0003158//endothelium development;GO:0001501//skeletal system development;GO:0048562//embryonic organ morphogenesis;GO:0006351//transcription, DNA-templated" gi|744588270|ref|XP_010986273.1|/1.16348e-118/PREDICTED: homeobox protein Hox-B5 [Camelus dromedarius] 17293 1936 0.206666667 0.12 -0.784271309 Down 0.179444507 Mesp2 mesoderm posterior 2 K09076|1|8e-165|583|mmu:17293|mesoderm posterior GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0009952//anterior/posterior pattern specification;GO:0007166//cell surface receptor signaling pathway;GO:0007509//mesoderm migration involved in gastrulation;GO:0006366//transcription from RNA polymerase II promoter gi|111955348|ref|NP_032615.2|/6.56846e-164/mesoderm posterior protein 2 [Mus musculus] 50994 688 0.223333333 0.13 -0.780686972 Down 0.179444507 Mtag2 metastasis associated gene 2 - - - - gi|1857776|gb|AAB48499.1|/6.893e-51/tumor metastasis associated gene product [Mus musculus] 66665 1649.2 10.58666667 10.07 -0.072184728 Down 0.1794163 Msantd3 Myb/SANT-like DNA-binding domain containing 3 - - GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding - gi|225543534|ref|NP_082413.2|/3.65847e-141/myb/SANT-like DNA-binding domain-containing protein 3 [Mus musculus] 70088 1382 11.25666667 10.73333333 -0.068681491 Down 0.1794163 Meaf6 MYST/Esa1-associated factor 6 K11344|1|2e-62|241|cge:100755375|chromatin modification-related protein EAF6 GO:0005815//microtubule organizing center;GO:0070775;GO:0043189//H4/H2A histone acetyltransferase complex;GO:0005815//microtubule organizing center;GO:0070775;GO:0043189//H4/H2A histone acetyltransferase complex GO:0005488//binding;GO:0005488//binding "GO:0043967//histone H4 acetylation;GO:0043966//histone H3 acetylation;GO:0006351//transcription, DNA-templated;GO:0043967//histone H4 acetylation;GO:0043966//histone H3 acetylation" gi|564352872|ref|XP_006238948.1|/1.93497e-68/PREDICTED: chromatin modification-related protein MEAF6 isoform X1 [Rattus norvegicus] 234663 4647 10.95333333 10.43 -0.070630822 Down 0.1794163 Dync1li2 "dynein, cytoplasmic 1 light intermediate chain 2" "K10416|1|0.0|986|mmu:234663|dynein light intermediate chain 1, cytosolic" GO:0005815//microtubule organizing center;GO:0030286//dynein complex;GO:0044444//cytoplasmic part GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0051640//organelle localization;GO:0002478;GO:0007010//cytoskeleton organization;GO:0051234//establishment of localization "gi|148679269|gb|EDL11216.1|/0/dynein, cytoplasmic 1 light intermediate chain 2, isoform CRA_a, partial [Mus musculus]" 257633 2236 18.13 18.94 0.063057406 Up 0.179406898 Acsf3 acyl-CoA synthetase family member 3 K18660|1|0.0|1161|mmu:257633|malonyl-CoA/methylmalonyl-CoA synthetase [EC:6.2.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0016878//acid-thiol ligase activity GO:0006631//fatty acid metabolic process;GO:0043649//dicarboxylic acid catabolic process "gi|113199775|ref|NP_659181.2|/0/acyl-CoA synthetase family member 3, mitochondrial precursor [Mus musculus]" 83486 3104 18.96333333 18.15 -0.063243032 Down 0.179406898 Rbm5 RNA binding motif protein 5 K13094|1|0.0|1118|mmu:83486|RNA-binding protein 5/10 GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0046872//metal ion binding "GO:0006915//apoptotic process;GO:0000380//alternative mRNA splicing, via spliceosome" gi|22507333|ref|NP_683732.1|/0/RNA-binding protein 5 [Mus musculus] 320311 8406 0.213333333 0.313333333 0.554588852 Up 0.179369288 Rnf152 ring finger protein 152 K15705|1|5e-109|400|mmu:320311|E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27] GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination;GO:0012501//programmed cell death;GO:0000209//protein polyubiquitination;GO:0012501//programmed cell death "gi|148707931|gb|EDL39878.1|/2.10843e-120/ring finger protein 152, partial [Mus musculus]" 107221 1393 0.326666667 0.223333333 -0.548620654 Down 0.179369288 Ffar4 free fatty acid receptor 4 K08425|1|0.0|647|mmu:107221|G protein-coupled receptor 120 "GO:0031224//intrinsic component of membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0004930//G-protein coupled receptor activity;GO:0008289//lipid binding GO:0006954//inflammatory response;GO:0009914//hormone transport;GO:0015758//glucose transport;GO:0050663//cytokine secretion;GO:0007166//cell surface receptor signaling pathway gi|32306532|ref|NP_861413.1|/0/free fatty acid receptor 4 [Mus musculus] 15559 2073 0.1 0.03 -1.736965594 Down 0.179322276 Htr2b 5-hydroxytryptamine (serotonin) receptor 2B K04157|1|0.0|863|mmu:15559|5-hydroxytryptamine receptor 2 GO:0016021//integral component of membrane;GO:0044424 GO:0005261//cation channel activity;GO:0004629//phospholipase C activity;GO:0008227//G-protein coupled amine receptor activity;GO:0005515//protein binding;GO:0043169//cation binding GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0001935//endothelial cell proliferation;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0043405//regulation of MAP kinase activity;GO:0046474//glycerophospholipid biosynthetic process;GO:0019932//second-messenger-mediated signaling;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0050663//cytokine secretion;GO:0001667//ameboidal-type cell migration;GO:0009266//response to temperature stimulus;GO:0014821;GO:0051592//response to calcium ion;GO:0048015//phosphatidylinositol-mediated signaling;GO:0050880//regulation of blood vessel size;GO:0032959//inositol trisphosphate biosynthetic process;GO:0048762//mesenchymal cell differentiation;GO:0051283//negative regulation of sequestering of calcium ion;GO:0048522;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0009152//purine ribonucleotide biosynthetic process;GO:0046889//positive regulation of lipid biosynthetic process;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0006816//calcium ion transport;GO:0007610//behavior;GO:0014897;GO:0009887//organ morphogenesis;GO:0032770//positive regulation of monooxygenase activity gi|54090|emb|CAA78824.1|/0/serotonin receptor [Mus musculus] 12775 1925 0.103333333 0.03 -1.784271309 Down 0.179322276 Ccr7 chemokine (C-C motif) receptor 7 K04182|1|0.0|679|mmu:12775|C-C chemokine receptor type 7 GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface GO:0019957//C-C chemokine binding;GO:0016493//C-C chemokine receptor activity;GO:0019957//C-C chemokine binding;GO:0016493//C-C chemokine receptor activity GO:0002237//response to molecule of bacterial origin;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0050852//T cell receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0002513//tolerance induction to self antigen;GO:0031346//positive regulation of cell projection organization;GO:0001771//immunological synapse formation;GO:0043066//negative regulation of apoptotic process;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032615//interleukin-12 production;GO:0097028//dendritic cell differentiation;GO:0002407//dendritic cell chemotaxis;GO:0060491//regulation of cell projection assembly;GO:0042098//T cell proliferation;GO:0007010//cytoskeleton organization;GO:0034694//response to prostaglandin;GO:0048247//lymphocyte chemotaxis;GO:0045063//T-helper 1 cell differentiation;GO:0043383//negative T cell selection;GO:0002524;GO:0072679//thymocyte migration;GO:0006898//receptor-mediated endocytosis;GO:0002920//regulation of humoral immune response;GO:0097021//lymphocyte migration into lymphoid organs;GO:0070098//chemokine-mediated signaling pathway;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0006909//phagocytosis;GO:0000302//response to reactive oxygen species;GO:0002468//dendritic cell antigen processing and presentation;GO:0002237//response to molecule of bacterial origin;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0050852//T cell receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0002513//tolerance induction to self antigen;GO:0031346//positive regulation of cell projection organization;GO:0001771//immunological synapse formation;GO:0043066//negative regulation of apoptotic process;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032615//interleukin-12 production;GO:0097028//dendritic cell differentiation;GO:0002407//dendritic cell chemotaxis;GO:0060491//regulation of cell projection assembly;GO:0042098//T cell proliferation;GO:0007010//cytoskeleton organization;GO:0034694//response to prostaglandin;GO:0048247//lymphocyte chemotaxis;GO:0045063//T-helper 1 cell differentiation;GO:0043383//negative T cell selection;GO:0002524;GO:0072679//thymocyte migration;GO:0006898//receptor-mediated endocytosis;GO:0002920//regulation of humoral immune response;GO:0097021//lymphocyte migration into lymphoid organs;GO:0070098//chemokine-mediated signaling pathway;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0006909//phagocytosis;GO:0000302//response to reactive oxygen species;GO:0002468//dendritic cell antigen processing and presentation gi|74185856|dbj|BAE32796.1|/0/unnamed protein product [Mus musculus] 56378 918 89.31333333 92.47666667 0.050213829 Up 0.179284667 Arpc3 "actin related protein 2/3 complex, subunit 3" "K05756|1|4e-101|370|mmu:56378|actin related protein 2/3 complex, subunit 3" - - - - 56050 3106 1.753333333 1.95 0.153373825 Up 0.179247057 Cyp39a1 "cytochrome P450, family 39, subfamily a, polypeptide 1" K07439|1|0.0|940|mmu:56050|24-hydroxycholesterol 7alpha-hydroxylase [EC:1.14.14.26] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0008395//steroid hydroxylase activity;GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0008395//steroid hydroxylase activity;GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0008395//steroid hydroxylase activity" GO:0006706//steroid catabolic process;GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0044707;GO:0006706//steroid catabolic process;GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0044707;GO:0006706//steroid catabolic process;GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0044707 gi|9256529|ref|NP_061375.1|/0/24-hydroxycholesterol 7-alpha-hydroxylase isoform 1 [Mus musculus] 114565 5682.29 2.05 1.85 -0.148098639 Down 0.179247057 Zbtb21 zinc finger and BTB domain containing 21 K09228|1|1e-18|99.4|nle:100601934|KRAB domain-containing zinc finger protein;K10510|2|2e-18|99.0|xtr:100488939|zinc finger and BTB domain-containing protein 38 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0000166//nucleotide binding;GO:0046914//transition metal ion binding;GO:0000166//nucleotide binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148671694|gb|EDL03641.1|/0/zinc finger protein 295, isoform CRA_b, partial [Mus musculus]" 233902 3431 1.773333333 1.97 0.151731885 Up 0.179247057 Fbxl19 F-box and leucine-rich repeat protein 19 K10285|1|0.0|1116|mmu:233902|F-box and leucine-rich repeat protein 19 - GO:0046914//transition metal ion binding - gi|40254240|ref|NP_766336.2|/0/F-box/LRR-repeat protein 19 [Mus musculus] 68166 4822.56 2.006666667 1.803333333 -0.154134893 Down 0.179247057 Spire1 spire homolog 1 (Drosophila) K02098|1|0.0|1063|rno:307348|spire GO:0043232;GO:0043231//intracellular membrane-bounded organelle GO:0008092//cytoskeletal protein binding GO:0007010//cytoskeleton organization;GO:0016192//vesicle-mediated transport "gi|148677693|gb|EDL09640.1|/0/spire homolog 1 (Drosophila), isoform CRA_d, partial [Mus musculus]" 233410 7292 7.046666667 6.646666667 -0.084309967 Down 0.179228252 Zfp592 zinc finger protein 592 K19325|1|0.0|2239|mmu:233410|zinc finger protein 592 - - - gi|37359842|dbj|BAC97899.1|/0/mKIAA0211 protein [Mus musculus] 21809 3401 7.233333333 7.633333333 0.077652556 Up 0.179228252 Tgfb3 "transforming growth factor, beta 3" K13377|1|0.0|766|ocu:100358982|transforming growth factor beta-3 "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0042383//sarcolemma;GO:0044297//cell body;GO:0044421" GO:0005160//transforming growth factor beta receptor binding;GO:0019838//growth factor binding;GO:0046983//protein dimerization activity GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007184//SMAD protein import into nucleus;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0030282//bone mineralization;GO:0003006//developmental process involved in reproduction;GO:0034405//response to fluid shear stress;GO:0043009//chordate embryonic development;GO:0031346//positive regulation of cell projection organization;GO:0001837//epithelial to mesenchymal transition;GO:0001666//response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0012502//induction of programmed cell death;GO:0040007//growth;GO:0042127//regulation of cell proliferation;GO:0060363//cranial suture morphogenesis;GO:0030856//regulation of epithelial cell differentiation;GO:0006260//DNA replication;GO:0044703;GO:0048545//response to steroid hormone;GO:0006366//transcription from RNA polymerase II promoter;GO:0034330;GO:0002719;GO:0007431//salivary gland development;GO:0043583//ear development;GO:0043066//negative regulation of apoptotic process;GO:0048598//embryonic morphogenesis;GO:0009306//protein secretion;GO:0009611//response to wounding;GO:0030324//lung development gi|533151987|ref|XP_005390203.1|/0/PREDICTED: transforming growth factor beta-3 [Chinchilla lanigera] 76375 2217 5.28 5.616666667 0.089176256 Up 0.17921885 Det1 de-etiolated homolog 1 (Arabidopsis) K10571|1|0.0|1148|cge:100770116|de-etiolated-1 - - - gi|625226471|ref|XP_007652632.1|/0/PREDICTED: DET1 homolog isoform X2 [Cricetulus griseus] 67878 5829.86 5.396666667 5.74 0.088982157 Up 0.17921885 Tmem33 transmembrane protein 33 - GO:0031224//intrinsic component of membrane;GO:0048770;GO:0031224//intrinsic component of membrane;GO:0048770;GO:0031224//intrinsic component of membrane;GO:0048770 - - "gi|148705834|gb|EDL37781.1|/6.31613e-146/transmembrane protein 33, isoform CRA_e, partial [Mus musculus]" 78929 2514 5.543333333 5.88 0.085062392 Up 0.17921885 Polr3h polymerase (RNA) III (DNA directed) polypeptide H K03022|1|2e-109|399|rno:300088|DNA-directed RNA polymerase III subunit RPC8 GO:0005815//microtubule organizing center;GO:0044451 GO:0034062//RNA polymerase activity "GO:0006952//defense response;GO:0002252;GO:0006351//transcription, DNA-templated" gi|625254629|ref|XP_007618657.1|/7.51204e-110/PREDICTED: DNA-directed RNA polymerase III subunit RPC8 isoform X3 [Cricetulus griseus] 66343 3302 5.273333333 5.613333333 0.090142539 Up 0.17921885 Tmem177 transmembrane protein 177 - GO:0031224//intrinsic component of membrane - - gi|30424705|ref|NP_780315.1|/1.9048e-180/transmembrane protein 177 [Mus musculus] 18572 6062 5.326666667 4.99 -0.094193187 Down 0.17921885 Pdcd11 programmed cell death 11 K14792|1|0.0|3299|mmu:18572|rRNA biogenesis protein RRP5 - - - gi|54607128|ref|NP_035183.2|/0/protein RRP5 homolog [Mus musculus] 21762 3000 95.31 92.21666667 -0.047600073 Down 0.179209448 Psmd2 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 2" K03028|1|0.0|1545|mmu:21762|26S proteasome regulatory subunit N1 GO:0000502//proteasome complex;GO:0000502//proteasome complex GO:0005488//binding;GO:0005488//binding GO:0009894;GO:0009894 "gi|148665168|gb|EDK97584.1|/0/mCG129789, isoform CRA_a, partial [Mus musculus]" 54388 864 1.05 0.9 -0.222392421 Down 0.179115424 Hils1 histone H1-like protein in spermatids 1 K11275|1|3e-08|61.2|myd:102765798|histone H1/5 - - - - 14235 4391 1.02 0.873333333 -0.223964841 Down 0.179115424 Foxm1 forkhead box M1 K09406|1|0.0|1185|mmu:14235|forkhead box protein M GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0019900//kinase binding "GO:0032872//regulation of stress-activated MAPK cascade;GO:0007275//multicellular organism development;GO:0006366//transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0008283//cell proliferation;GO:0006302//double-strand break repair;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0044767//single-organism developmental process;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048523//negative regulation of cellular process" gi|49900136|gb|AAH75723.1|/0/Forkhead box M1 [Mus musculus] 93711 4763 0.91 1.063333333 0.224655473 Up 0.179115424 Pcdhga3 "protocadherin gamma subfamily A, 3" K16495|1|0.0|1730|mmu:93711|protocadherin gamma subfamily A GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0007041//lysosomal transport;GO:0016337//single organismal cell-cell adhesion;GO:0048284//organelle fusion gi|18087757|ref|NP_291064.1|/0/protocadherin gamma-A3 precursor [Mus musculus] 100503199 626 0.903333333 1.053333333 0.221631707 Up 0.179115424 5430416N02Rik RIKEN cDNA 5430416N02 gene - - - - "gi|148688347|gb|EDL20294.1|/3.1509e-17/mCG1030747, isoform CRA_a [Mus musculus]" 72962 2042 0.91 1.06 0.220125814 Up 0.179115424 Tymp thymidine phosphorylase K00758|1|0.0|889|mmu:72962|thymidine phosphorylase [EC:2.4.2.4] GO:0044444//cytoplasmic part "GO:0016763//transferase activity, transferring pentosyl groups;GO:0016758//transferase activity, transferring hexosyl groups;GO:0070851//growth factor receptor binding" GO:0048869//cellular developmental process;GO:0006259//DNA metabolic process;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0006213//pyrimidine nucleoside metabolic process;GO:0009117//nucleotide metabolic process;GO:0042221//response to chemical;GO:0007005//mitochondrion organization;GO:0009112;GO:0008655//pyrimidine-containing compound salvage gi|19923857|ref|NP_612175.1|/0/thymidine phosphorylase [Mus musculus] 320148 3462 0.21 0.123333333 -0.767826558 Down 0.179087217 B430306N03Rik RIKEN cDNA B430306N03 gene K14364|1|2e-32|144|fca:101090615|trem-like transcript 2 protein;K06742|2|2e-17|94.7|cge:100771904|natural cytotoxicity triggering receptor 2;K20395|4|3e-07|60.8|asn:102380808|CO300B/D/F antigen - - - "gi|148691662|gb|EDL23609.1|/2.91374e-155/mCG145377, partial [Mus musculus]" 226970 2738 0.126666667 0.216666667 0.7744403 Up 0.179087217 Arhgef4 Rho guanine nucleotide exchange factor (GEF) 4 K05769|1|0.0|961|mmu:226970|Rho guanine nucleotide exchange factor 4 GO:0044424 GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0005515//protein binding GO:0007266//Rho protein signal transduction;GO:0030031//cell projection assembly "gi|148682512|gb|EDL14459.1|/0/Rho guanine nucleotide exchange factor (GEF) 4, isoform CRA_a [Mus musculus]" 407821 6676.3 0.763333333 0.906666667 0.248259053 Up 0.179077814 Znrf3 zinc and ring finger 3 K16273|1|0.0|1636|mmu:407821|E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27] GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0046914//transition metal ion binding;GO:0001664//G-protein coupled receptor binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0001664//G-protein coupled receptor binding;GO:0019787//ubiquitin-like protein transferase activity GO:0035567//non-canonical Wnt signaling pathway;GO:0032446//protein modification by small protein conjugation;GO:0019941//modification-dependent protein catabolic process;GO:0030178//negative regulation of Wnt signaling pathway;GO:0008283//cell proliferation;GO:0035567//non-canonical Wnt signaling pathway;GO:0032446//protein modification by small protein conjugation;GO:0019941//modification-dependent protein catabolic process;GO:0030178//negative regulation of Wnt signaling pathway;GO:0008283//cell proliferation gi|124286866|ref|NP_001074393.1|/0/E3 ubiquitin-protein ligase ZNRF3 isoform 1 precursor [Mus musculus] 74519 1944 0.886666667 0.746666667 -0.247927513 Down 0.179077814 Cyp2j9 "cytochrome P450, family 2, subfamily j, polypeptide 9" "K07418|1|0.0|992|mmu:74519|cytochrome P450, family 2, subfamily J [EC:1.14.14.1]" GO:0031090//organelle membrane "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0044710 "gi|148698965|gb|EDL30912.1|/0/cytochrome P450, family 2, subfamily j, polypeptide 9, partial [Mus musculus]" 80901 1893 0.033333333 0.106666667 1.678071905 Up 0.179068412 Cxcr6 chemokine (C-X-C motif) receptor 6 K04191|1|5e-175|617|mmu:80901|C-X-C chemokine receptor type 6 GO:0031224//intrinsic component of membrane GO:0004950//chemokine receptor activity GO:0019221//cytokine-mediated signaling pathway;GO:0051480//regulation of cytosolic calcium ion concentration gi|568964419|ref|XP_006512464.1|/2.11067e-175/PREDICTED: C-X-C chemokine receptor type 6 isoform X1 [Mus musculus] 100417675 1910 0.033333333 0.1 1.584962501 Up 0.179068412 Nlrp5-ps "NLR family, pyrin domain containing 5, pseudogene" "K12800|1|9e-54|214|cmy:102936366|NACHT, LRR and PYD domains-containing protein 3" GO:0032991//macromolecular complex;GO:0044448;GO:0031981//nuclear lumen GO:0005488//binding GO:0010608//posttranscriptional regulation of gene expression;GO:0043009//chordate embryonic development;GO:0006461//protein complex assembly;GO:0019953//sexual reproduction;GO:0009653//anatomical structure morphogenesis "gi|148692429|gb|EDL24376.1|/3.91264e-161/mCG113308, isoform CRA_c, partial [Mus musculus]" 13206 2772 0.1 0.033333333 -1.584962501 Down 0.179068412 Ddx4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 K13982|1|0.0|1273|mmu:13206|probable ATP-dependent RNA helicase DDX4 [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle;GO:0043186//P granule;GO:0043231//intracellular membrane-bounded organelle;GO:0043186//P granule "GO:0032550;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0042623//ATPase activity, coupled" GO:0048870//cell motility;GO:0007127//meiosis I;GO:0048232//male gamete generation;GO:0032502//developmental process;GO:0008104//protein localization;GO:0048870//cell motility;GO:0007127//meiosis I;GO:0048232//male gamete generation;GO:0032502//developmental process;GO:0008104//protein localization "gi|148686462|gb|EDL18409.1|/0/DEAD (Asp-Glu-Ala-Asp) box polypeptide 4, partial [Mus musculus]" 56739 2055 0.096666667 0.03 -1.688055994 Down 0.179068412 Rec8 REC8 meiotic recombination protein "K13054|1|0.0|952|mmu:56739|meiotic recombination protein REC8, animal type" GO:0000798//nuclear cohesin complex;GO:0000795//synaptonemal complex;GO:0043073//germ cell nucleus;GO:0000777//condensed chromosome kinetochore GO:0005488//binding GO:0007127//meiosis I;GO:0007281//germ cell development gi|31982699|ref|NP_064386.2|/0/meiotic recombination protein REC8 homolog [Mus musculus] 17063 2969 0.11 0.036666667 -1.584962501 Down 0.179068412 Muc13 "mucin 13, epithelial transmembrane" K17298|1|0.0|677|mmu:17063|mucin-13 GO:0031224//intrinsic component of membrane - - "gi|148665438|gb|EDK97854.1|/0/mucin 13, epithelial transmembrane, isoform CRA_b [Mus musculus]" 234911 2132 0.03 0.096666667 1.688055994 Up 0.179068412 Mmp27 matrix metallopeptidase 27 K08005|1|0.0|1092|mmu:234911|matrix metalloproteinase-27 [EC:3.4.24.-] - - - gi|894216250|ref|NP_001297646.1|/0/matrix metalloproteinase-27 [Mus musculus] 234155 1839 0.033333333 0.1 1.584962501 Up 0.179068412 Mboat4 membrane bound O-acyltransferase domain containing 4 K13517|1|2e-25|119|ssc:100152017|lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-] GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0008374//O-acyltransferase activity GO:0018190 gi|187283003|ref|NP_001119786.1|/0/ghrelin O-acyltransferase [Mus musculus] 16174 4889 0.033333333 0.103333333 1.632268215 Up 0.179068412 Il18rap interleukin 18 receptor accessory protein K05174|1|0.0|1216|mmu:16174|interleukin 18 receptor accessory protein GO:0031224//intrinsic component of membrane GO:0004896//cytokine receptor activity GO:0006952//defense response;GO:0007154//cell communication gi|6754326|ref|NP_034683.1|/0/interleukin-18 receptor accessory protein precursor [Mus musculus] 69852 4101 2.723333333 2.966666667 0.123469258 Up 0.179040205 Tcf23 transcription factor 23 - - GO:0005515//protein binding GO:0048513//animal organ development;GO:0048869//cellular developmental process gi|16716369|ref|NP_444315.1|/8.54769e-93/transcription factor 23 [Mus musculus] 269470 3440 2.763333333 3 0.1185529 Up 0.179040205 Wdr3 WD repeat domain 3 K14556|1|0.0|1722|mmu:269470|U3 small nucleolar RNA-associated protein 12 GO:0005635//nuclear envelope;GO:0031981//nuclear lumen - - "gi|148675697|gb|EDL07644.1|/0/WD repeat domain 3, isoform CRA_c, partial [Mus musculus]" 73288 3966.23 2.88 3.12 0.115477217 Up 0.179040205 Vps50 VPS50 EARP/GARPII complex subunit - - - - - 56404 6385.61 2.896666667 3.14 0.116370883 Up 0.179040205 Trip4 thyroid hormone receptor interactor 4 K15631|1|7e-74|283|dvi:Dvir_GJ19188|molybdenum cofactor sulfurtransferase [EC:2.8.1.9] GO:0015630//microtubule cytoskeleton;GO:0031981//nuclear lumen GO:0003712//transcription cofactor activity;GO:0046914//transition metal ion binding;GO:0005102//receptor binding "GO:0006351//transcription, DNA-templated" gi|625233938|ref|XP_007608113.1|/0/PREDICTED: activating signal cointegrator 1 isoform X2 [Cricetulus griseus] 11416 3122 2.846666667 3.086666667 0.116776124 Up 0.179040205 Slc33a1 "solute carrier family 33 (acetyl-CoA transporter), member 1" "K03372|1|0.0|1053|mmu:11416|MFS transporter, PAT family, solute carrier family 33 (acetyl-CoA transportor), member 1 [EC:2.3.1.-]" - - - - 215257 1647 0.213333333 0.31 0.539158811 Up 0.179011997 Il1f9 "interleukin 1 family, member 9" "K05487|1|9e-111|403|mmu:215257|interleukin 1 family, member 9" GO:0044421 GO:0005126//cytokine receptor binding GO:0001819//positive regulation of cytokine production;GO:0006952//defense response gi|224994269|ref|NP_705731.2|/7.59135e-110/interleukin-36 gamma [Mus musculus] 241943 2506 0.32 0.22 -0.540568381 Down 0.179011997 Ccdc144b coiled-coil domain containing 144B K17299|1|2e-49|199|ptr:465138|POTE ankyrin domain family protein;K11837|4|2e-41|173|ggo:101126875|ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12] - - - gi|225543504|ref|NP_848505.2|/0/coiled-coil domain containing 144B [Mus musculus] 71984 1910 11.52333333 11.01 -0.065743634 Down 0.178936778 Sars2 seryl-aminoacyl-tRNA synthetase 2 K01875|1|0.0|971|mmu:71984|seryl-tRNA synthetase [EC:6.1.1.11] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation "gi|228008415|ref|NP_076126.2|/0/serine--tRNA ligase, mitochondrial precursor [Mus musculus]" 20529 3764 10.7 11.21 0.067175482 Up 0.178936778 Slc31a1 "solute carrier family 31, member 1" "K14686|1|6e-77|292|mmu:20529|solute carrier family 31 (copper transporter), member 1" GO:0031224//intrinsic component of membrane GO:0022890//inorganic cation transmembrane transporter activity GO:0006825//copper ion transport gi|227116313|ref|NP_780299.2|/5.06587e-76/high affinity copper uptake protein 1 [Mus musculus] 20810 1328 10.09 10.6 0.07113809 Up 0.178936778 Srm spermidine synthase K00797|1|1e-162|575|mmu:20810|spermidine synthase [EC:2.5.1.16] GO:0044444//cytoplasmic part "GO:0042802//identical protein binding;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups" GO:0006596//polyamine biosynthetic process;GO:0044710 gi|635111691|ref|XP_007978768.1|/1.7848e-164/PREDICTED: spermidine synthase [Chlorocebus sabaeus] 98366 2207.63 11.3 10.79 -0.066627908 Down 0.178936778 Smap1 small ArfGAP 1 K12486|1|1e-113|412|mmu:98366|stromal membrane-associated protein GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0044424 GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0043087//regulation of GTPase activity;GO:0048259//regulation of receptor-mediated endocytosis;GO:0030036//actin cytoskeleton organization;GO:0032012//regulation of ARF protein signal transduction;GO:0030218//erythrocyte differentiation;GO:0043087//regulation of GTPase activity;GO:0048259//regulation of receptor-mediated endocytosis;GO:0030036//actin cytoskeleton organization;GO:0030218//erythrocyte differentiation;GO:0043087//regulation of GTPase activity;GO:0048259//regulation of receptor-mediated endocytosis;GO:0030036//actin cytoskeleton organization;GO:0032012//regulation of ARF protein signal transduction;GO:0030218//erythrocyte differentiation gi|28077013|ref|NP_082810.1|/7.52361e-161/stromal membrane-associated protein 1 isoform 1 [Mus musculus] 69151 1778 9.96 10.47 0.072043795 Up 0.178936778 Lzic leucine zipper and CTNNBIP1 domain containing - - - - gi|568931845|ref|XP_006539215.1|/9.94633e-87/PREDICTED: protein LZIC isoform X2 [Mus musculus] 30940 4432 10.15 9.643333333 -0.073875905 Down 0.178936778 Usp25 ubiquitin specific peptidase 25 K11849|1|0.0|2053|mmu:30940|ubiquitin carboxyl-terminal hydrolase 25/28 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle GO:0032182//ubiquitin-like protein binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0016790//thiolester hydrolase activity GO:0016579//protein deubiquitination;GO:0019941//modification-dependent protein catabolic process gi|31980712|ref|NP_038946.2|/0/ubiquitin carboxyl-terminal hydrolase 25 [Mus musculus] 12443 3796 17.96333333 17.17666667 -0.064604994 Down 0.178917974 Ccnd1 cyclin D1 K04503|1|3e-145|519|mmu:12443|cyclin D1 GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0043234//protein complex GO:0016301//kinase activity;GO:0019887//protein kinase regulator activity;GO:0019900//kinase binding GO:0006984//ER-nucleus signaling pathway;GO:0033598//mammary gland epithelial cell proliferation;GO:1901990//regulation of mitotic cell cycle phase transition;GO:0016055//Wnt signaling pathway;GO:0003006//developmental process involved in reproduction;GO:0007589//body fluid secretion;GO:0043627//response to estrogen;GO:0009411//response to UV;GO:0044773//mitotic DNA damage checkpoint;GO:0051384//response to glucocorticoid;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0010038//response to metal ion;GO:0009887//organ morphogenesis;GO:0097305//response to alcohol;GO:0010212//response to ionizing radiation;GO:0030855//epithelial cell differentiation gi|6680868|ref|NP_031657.1|/2.57349e-144/G1/S-specific cyclin-D1 [Mus musculus] 94112 3370.74 20.47 19.68333333 -0.056536543 Down 0.178917974 Med15 mediator complex subunit 15 K15157|1|2e-165|585|cge:100754109|mediator of RNA polymerase II transcription subunit 15 GO:0044424 - "GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|74151422|dbj|BAE38826.1|/2.42433e-143/unnamed protein product [Mus musculus] 73046 1002 78.59333333 81.54666667 0.053218965 Up 0.178917974 Glrx5 glutaredoxin 5 K07390|1|1e-53|212|mmu:73046|monothiol glutaredoxin - - - - 66656 1708.34 88.67666667 91.59666667 0.046740557 Up 0.178908571 Eef1d eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) K15410|1|0.0|1082|rno:300033|elongation factor 1-delta - - - - 22222 7765 2.226666667 2.016666667 -0.14291296 Down 0.178870962 Ubr1 ubiquitin protein ligase E3 component n-recognin 1 K10625|1|0.0|3454|mmu:22222|E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27] - - - - 69719 7038.79 2.373333333 2.16 -0.135883428 Down 0.178870962 Cad "carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase" K11540|1|0.0|3938|mmu:69719|carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3] GO:0032991//macromolecular complex;GO:0034399//nuclear periphery;GO:0044297//cell body;GO:0033267;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0034399//nuclear periphery;GO:0044297//cell body;GO:0033267;GO:0044444//cytoplasmic part "GO:0016301//kinase activity;GO:0032550;GO:0005515//protein binding;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0016743//carboxyl- or carbamoyltransferase activity;GO:0016301//kinase activity;GO:0032550;GO:0005515//protein binding;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0016743//carboxyl- or carbamoyltransferase activity" GO:0009209;GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0006468//protein phosphorylation;GO:0009209;GO:0019856//pyrimidine nucleobase biosynthetic process;GO:0006468//protein phosphorylation gi|575501556|ref|NP_001276451.1|/0/CAD protein isoform 2 [Mus musculus] 207474 4822 2.316666667 2.106666667 -0.137088419 Down 0.178870962 Kctd12b potassium channel tetramerisation domain containing 12b "K03849|1|1e-13|82.4|cmk:103177229|alpha-1,3-glucosyltransferase [EC:2.4.1.265];K15074|2|4e-09|67.4|tad:TRIADDRAFT_4579|BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein;K11835|5|2e-07|61.6|sko:100377510|ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.4.19.12]" GO:0043234//protein complex GO:0015075//ion transmembrane transporter activity GO:0007186//G-protein coupled receptor signaling pathway gi|30425146|ref|NP_780638.1|/1.75881e-169/potassium channel tetramerisation domain containing 12b [Mus musculus] 258961 1550 1.96 2.166666667 0.144623563 Up 0.178870962 Olfr631 olfactory receptor 631 K04257|1|1e-174|615|mmu:258961|olfactory receptor - GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway gi|116089294|ref|NP_667170.2|/8.49646e-174/olfactory receptor 631 [Mus musculus] 24135 4685.76 4.503333333 4.21 -0.097173036 Down 0.178739328 Zfp68 zinc finger protein 68 K09228|1|0.0|1212|mmu:24135|KRAB domain-containing zinc finger protein - GO:0043169//cation binding;GO:0043169//cation binding;GO:0043169//cation binding - gi|7305647|ref|NP_038872.1|/0/zinc finger protein 68 isoform a [Mus musculus] 76441 6045 4.463333333 4.173333333 -0.096921398 Down 0.178739328 Daam2 dishevelled associated activator of morphogenesis 2 K04512|1|0.0|1993|mmu:76441|dishevelled associated activator of morphogenesis - - - gi|116089318|ref|NP_001008232.2|/0/disheveled-associated activator of morphogenesis 2 [Mus musculus] 14121 1479 0.14 0.233333333 0.736965594 Up 0.178739328 Fbp1 fructose bisphosphatase 1 "K03841|1|0.0|674|mmu:14121|fructose-1,6-bisphosphatase I [EC:3.1.3.11]" GO:0044444//cytoplasmic part GO:0030246//carbohydrate binding;GO:0032550;GO:0043169//cation binding;GO:0050308//sugar-phosphatase activity GO:0006094//gluconeogenesis;GO:0007265//Ras protein signal transduction;GO:0032868//response to insulin;GO:0032026//response to magnesium ion;GO:0006796//phosphate-containing compound metabolic process;GO:0006096//glycolytic process;GO:0044710;GO:0042493//response to drug;GO:0016049//cell growth;GO:0051260//protein homooligomerization "gi|9506589|ref|NP_062268.1|/0/fructose-1,6-bisphosphatase 1 [Mus musculus]" 69303 771 0.14 0.233333333 0.736965594 Up 0.178739328 1700001G11Rik RIKEN cDNA 1700001G11 gene - - - - - 53604 3674 0.223333333 0.133333333 -0.744161096 Down 0.178739328 Zpbp zona pellucida binding protein - GO:0043234//protein complex;GO:0030141//secretory granule;GO:0043234//protein complex;GO:0030141//secretory granule - GO:0035036//sperm-egg recognition;GO:0003006//developmental process involved in reproduction;GO:0035036//sperm-egg recognition;GO:0003006//developmental process involved in reproduction gi|7657605|ref|NP_056600.1|/0/zona pellucida-binding protein 1 isoform 1 [Mus musculus] 78771 4289 0.61 0.486666667 -0.325875279 Down 0.1786265 Mctp1 "multiple C2 domains, transmembrane 1" K19938|1|8e-20|102|obi:106875810|rabphilin-3A;K19907|3|5e-19|100|hro:HELRODRAFT_64105|synaptotagmin-7 - - - gi|532080920|ref|XP_005326214.1|/0/PREDICTED: multiple C2 and transmembrane domain-containing protein 1 isoform X2 [Ictidomys tridecemlineatus] 100502764 713 0.573333333 0.456666667 -0.328232672 Down 0.1786265 Gm16617 "predicted gene, 16617" - - - - - 13361 5307 0.45 0.566666667 0.332575339 Up 0.1786265 Dhfr dihydrofolate reductase K00287|1|1e-103|381|mmu:13361|dihydrofolate reductase [EC:1.5.1.3] - "GO:0003723//RNA binding;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0072341//modified amino acid binding" GO:0010243//response to organonitrogen compound;GO:0006544//glycine metabolic process;GO:0009117//nucleotide metabolic process;GO:0009396//folic acid-containing compound biosynthetic process;GO:0014070//response to organic cyclic compound gi|7106289|ref|NP_034179.1|/1.20435e-102/dihydrofolate reductase [Mus musculus] 320802 3230 0.223333333 0.323333333 0.533823652 Up 0.17858889 Ifitm10 interferon induced transmembrane protein 10 K06566|1|3e-91|339|mmu:320802|interferon induced transmembrane protein - - - "gi|148686194|gb|EDL18141.1|/2.1589e-120/RIKEN cDNA 6330512M04, partial [Mus musculus]" 76877 2620 0.223333333 0.323333333 0.533823652 Up 0.17858889 Rab36 "RAB36, member RAS oncogene family" K07922|1|1e-153|546|mmu:76877|Ras-related protein Rab-36 GO:0043231//intracellular membrane-bounded organelle GO:0032550 GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization "gi|148699986|gb|EDL31933.1|/4.78834e-178/RAB36, member RAS oncogene family, isoform CRA_b, partial [Mus musculus]" 320376 6142 1.826666667 1.64 -0.155517578 Down 0.178560683 Bcorl1 BCL6 co-repressor-like 1 K10683|1|2e-20|105|ecb:100053962|BRCA1-associated RING domain protein 1 GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" gi|125347764|ref|NP_848897.3|/0/BCL-6 corepressor-like protein 1 [Mus musculus] 75785 6683 17.87333333 17.1 -0.063812393 Down 0.178513671 Klhl24 kelch-like 24 K10461|1|0.0|1201|cge:100758788|kelch-like protein 24/35 GO:0044424;GO:0043025//neuronal cell body;GO:0043005//neuron projection - - gi|26381170|dbj|BAB29759.2|/0/unnamed protein product [Mus musculus] 70804 3022 18.32333333 19.09666667 0.059638858 Up 0.178513671 Pgrmc2 progesterone receptor membrane component 2 K17278|1|8e-95|351|rno:361940|membrane-associated progesterone receptor component GO:0031224//intrinsic component of membrane GO:0046906//tetrapyrrole binding - gi|226442772|ref|NP_081834.1|/7.15413e-94/membrane-associated progesterone receptor component 2 [Mus musculus] 18099 4507 3.193333333 3.456666667 0.114318333 Up 0.178419647 Nlk nemo like kinase K04468|1|0.0|854|rno:497961|nemo like kinase [EC:2.7.11.24] GO:0043231//intracellular membrane-bounded organelle GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0044389//ubiquitin-like protein ligase binding;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding "GO:0006351//transcription, DNA-templated;GO:0042501//serine phosphorylation of STAT protein;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0016055//Wnt signaling pathway" gi|149408132|ref|NP_032728.3|/0/serine/threonine-protein kinase NLK [Mus musculus] 70292 6617 3.66 3.396666667 -0.107724003 Down 0.178419647 Afap1 actin filament associated protein 1 K18616|1|0.0|1191|mmu:70292|actin filament associated protein 1 GO:0005924//cell-substrate adherens junction;GO:0015629//actin cytoskeleton GO:0008289//lipid binding;GO:0019904//protein domain specific binding GO:0009612//response to mechanical stimulus;GO:0007165//signal transduction "gi|148705554|gb|EDL37501.1|/0/RIKEN cDNA 2600003E23, isoform CRA_b, partial [Mus musculus]" 330427 3862 1.08 1.24 0.199308808 Up 0.178419647 9330102E08Rik RIKEN cDNA 9330102E08 gene - - - - "gi|148667452|gb|EDK99868.1|/2.42378e-73/mCG144866, partial [Mus musculus]" 320400 2491 3.39 3.65 0.106611191 Up 0.178419647 Gm16897 "predicted gene, 16897" K06474|1|1e-19|101|mmu:12490|CD34 antigen GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0044421 GO:0005515//protein binding;GO:0043168//anion binding GO:0097205//renal filtration;GO:0010467//gene expression;GO:0072008;GO:0048534//hematopoietic or lymphoid organ development;GO:0050673//epithelial cell proliferation;GO:0006809//nitric oxide biosynthetic process;GO:0050710//negative regulation of cytokine secretion;GO:0007596//blood coagulation;GO:0060055//angiogenesis involved in wound healing;GO:0070925//organelle assembly;GO:0042476//odontogenesis;GO:0001819//positive regulation of cytokine production;GO:0070265//necrotic cell death;GO:0050715//positive regulation of cytokine secretion;GO:0001570//vasculogenesis;GO:0009064//glutamine family amino acid metabolic process;GO:0007267//cell-cell signaling;GO:0007155//cell adhesion;GO:0006928//movement of cell or subcellular component;GO:0008015//blood circulation;GO:0001818//negative regulation of cytokine production;GO:0036301 "gi|148680987|gb|EDL12934.1|/8.62638e-58/mCG146144, partial [Mus musculus]" 234353 9437.08 1.646666667 1.463333333 -0.170290102 Down 0.178372635 Psd3 pleckstrin and Sec7 domain containing 3 K12494|1|0.0|1948|mmu:234353|PH and SEC7 domain-containing protein - - - - 244548 4709 1.623333333 1.443333333 -0.169554747 Down 0.178372635 Elmod2 ELMO/CED-12 domain containing 2 K04139|1|3e-08|64.7|gga:426044|adrenergic receptor alpha-2B GO:0043232;GO:0043232 - GO:0043087//regulation of GTPase activity;GO:0002697;GO:0006897//endocytosis;GO:0043087//regulation of GTPase activity;GO:0002697;GO:0006897//endocytosis gi|283436077|ref|NP_848851.3|/1.40208e-171/ELMO domain-containing protein 2 [Mus musculus] 52466 1990 1.443333333 1.626666667 0.172514123 Up 0.178372635 Slc46a1 "solute carrier family 46, member 1" "K14613|1|0.0|810|mmu:52466|MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1/3" GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044424 GO:0051183//vitamin transporter activity;GO:0019842//vitamin binding;GO:0051184 GO:0006835//dicarboxylic acid transport;GO:0044763;GO:0051181//cofactor transport gi|60359814|dbj|BAD90126.1|/0/mFLJ00234 protein [Mus musculus] 56323 2327 69.46333333 66.89 -0.054461098 Down 0.178306819 Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 K09511|1|0.0|690|rno:313811|DnaJ homolog subfamily B member 5 - - - - 330695 1242 0.723333333 0.596666667 -0.277735455 Down 0.178297416 Ctxn1 cortexin 1 - GO:0016020//membrane - - gi|148690044|gb|EDL21991.1|/5.53534e-72/cortexin 1 [Mus musculus] 105651 1852 0.59 0.716666667 0.2805873 Up 0.178297416 Ppp1r3e "protein phosphatase 1, regulatory (inhibitor) subunit 3E" K07189|1|8e-106|387|mmu:105651|protein phosphatase 1 regulatory subunit 3A/B/C/D/E - - - gi|268835745|ref|NP_001161380.1|/6.55032e-105/protein phosphatase 1 regulatory subunit 3E [Mus musculus] 20371 3690 0.61 0.74 0.278716028 Up 0.178297416 Foxp3 forkhead box P3 K10163|1|0.0|801|mmu:20371|forkhead box P3 - - - gi|16905075|ref|NP_473380.1|/0/forkhead box protein P3 [Mus musculus] 239368 2376 0.63 0.763333333 0.276961364 Up 0.178297416 Erich5 glutamate rich 5 K02908|1|5e-06|55.8|cge:103162454|large subunit ribosomal protein L30e - - - gi|74189232|dbj|BAE22665.1|/2.9841e-177/unnamed protein product [Mus musculus] 66379 741 73.98333333 71.42 -0.050872169 Down 0.178278611 Cox14 cytochrome c oxidase assembly protein 14 K18181|1|7e-25|115|ecb:106783320|cytochrome c oxidase assembly factor 14 GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane - GO:0008535//respiratory chain complex IV assembly "gi|148672166|gb|EDL04113.1|/6.86294e-37/RIKEN cDNA 2310016M24, partial [Mus musculus]" 73822 1702 2.31 2.53 0.131244533 Up 0.178259807 Mfsd12 major facilitator superfamily domain containing 12 - GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization gi|568968755|ref|XP_006514282.1|/0/PREDICTED: major facilitator superfamily domain-containing protein 12 isoform X1 [Mus musculus] 76813 2215 2.453333333 2.676666667 0.125694221 Up 0.178259807 Armc6 armadillo repeat containing 6 K08844|1|4e-09|66.2|bfo:BRAFLDRAFT_119973|leucine-rich repeat kinase 2 [EC:2.7.11.1];K17546|2|5e-09|65.9|tad:TRIADDRAFT_63635|probable inactive protein kinase-like protein SgK071 - - - "gi|148696855|gb|EDL28802.1|/0/mCG23104, isoform CRA_b, partial [Mus musculus]" 68364 4649 2.586666667 2.363333333 -0.130271025 Down 0.178259807 0610030E20Rik RIKEN cDNA 0610030E20 gene - - - - gi|568942720|ref|XP_006506597.1|/3.22064e-83/PREDICTED: UPF0561 protein C2orf68 homolog isoform X1 [Mus musculus] 72018 2950.28 6.653333333 7.046666667 0.082863656 Up 0.178222197 Fundc1 FUN14 domain containing 1 K17986|1|5e-71|272|rno:363442|FUN14 domain-containing protein 1 - - - - 232314 3641 10.16333333 9.663333333 -0.072780817 Down 0.178222197 Ppp4r2 "protein phosphatase 4, regulatory subunit 2" K15425|1|0.0|707|mmu:232314|serine/threonine-protein phosphatase 4 regulatory subunit 2 GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen;GO:0008287//protein serine/threonine phosphatase complex GO:0019888//protein phosphatase regulator activity;GO:0005515//protein binding GO:0006396//RNA processing;GO:0000018//regulation of DNA recombination;GO:0036211//protein modification process gi|33636709|ref|NP_891984.1|/0/serine/threonine-protein phosphatase 4 regulatory subunit 2 [Mus musculus] 57315 2235 7.076666667 7.463333333 0.076750157 Up 0.178222197 Wdr46 WD repeat domain 46 K14768|1|0.0|1113|mmu:57315|U3 small nucleolar RNA-associated protein 7 - - - gi|10181122|ref|NP_065628.1|/0/WD repeat-containing protein 46 [Mus musculus] 66882 2833 19.41333333 20.17666667 0.055639996 Up 0.178222197 Bzw1 basic leucine zipper and W2 domains 1 K03260|1|5e-06|56.2|hmg:101237497|translation initiation factor 4G - - - gi|640823833|ref|XP_008068959.1|/0/PREDICTED: basic leucine zipper and W2 domain-containing protein 1 isoform X1 [Tarsius syrichta] 225055 4013 7.2 6.806666667 -0.081048446 Down 0.178222197 Fbxo11 F-box protein 11 K10297|1|0.0|1804|mmu:225055|F-box protein 11 GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0008276//protein methyltransferase activity GO:0018216//peptidyl-arginine methylation;GO:0050954//sensory perception of mechanical stimulus;GO:0032446//protein modification by small protein conjugation;GO:0019941//modification-dependent protein catabolic process gi|124486644|ref|NP_001074503.1|/0/F-box only protein 11 [Mus musculus] 13684 4999 19.98 19.22 -0.055948247 Down 0.178222197 Eif4e eukaryotic translation initiation factor 4E K03259|1|7e-118|428|phd:102327611|translation initiation factor 4E GO:0035770//ribonucleoprotein granule;GO:0031332//RNAi effector complex;GO:0034518//RNA cap binding complex "GO:0008135//translation factor activity, RNA binding;GO:0031369//translation initiation factor binding" GO:0006412//translation;GO:0030323//respiratory tube development;GO:0044772//mitotic cell cycle phase transition gi|556737644|ref|XP_005964407.1|/6.18273e-117/PREDICTED: eukaryotic translation initiation factor 4E [Pantholops hodgsonii] 71989 1827 6.953333333 7.34 0.078075311 Up 0.178222197 Rpusd4 RNA pseudouridylate synthase domain containing 4 K01855|1|1e-97|359|mgp:100543853|tRNA pseudouridine38/39 synthase [EC:5.4.99.45];K15265|2|3e-29|132|smm:Smp_194510|21S rRNA pseudouridine2819 synthase [EC:5.4.99.43] GO:0043231//intracellular membrane-bounded organelle GO:0016866//intramolecular transferase activity;GO:0003676//nucleic acid binding GO:0016070//RNA metabolic process gi|58037279|ref|NP_082316.1|/0/RNA pseudouridylate synthase domain-containing protein 4 [Mus musculus] 76932 3277 6.583333333 6.97 0.082340409 Up 0.178222197 Arfip2 ADP-ribosylation factor interacting protein 2 K20314|1|6e-165|584|cge:100760054|arfaptin GO:0044444//cytoplasmic part;GO:0031252//cell leading edge GO:0005515//protein binding GO:0007010//cytoskeleton organization gi|725548711|ref|XP_010335315.1|/3.34162e-169/PREDICTED: arfaptin-2 isoform X1 [Saimiri boliviensis boliviensis] 19305 3141.87 11.05 10.55333333 -0.066347615 Down 0.178222197 Pex5 peroxisomal biogenesis factor 5 K13342|1|0.0|1187|mmu:19305|peroxin-5 - - - gi|113930737|ref|NP_033021.2|/0/peroxisomal biogenesis factor 5 isoform 1 [Mus musculus] 232906 8393 10.77666667 10.27333333 -0.069006646 Down 0.178222197 Arhgap35 Rho GTPase activating protein 35 K05732|1|0.0|2774|mmu:232906|glucocorticoid receptor DNA-binding factor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part GO:0032550;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0007166//cell surface receptor signaling pathway;GO:0014020;GO:0022604//regulation of cell morphogenesis;GO:0007420//brain development;GO:0001654//eye development;GO:0006935//chemotaxis;GO:0043114//regulation of vascular permeability" gi|75677442|ref|NP_766327.3|/0/rho GTPase-activating protein 35 [Mus musculus] 20185 8328.9 17.18666667 17.94666667 0.062426146 Up 0.178222197 Ncor1 nuclear receptor co-repressor 1 K04650|1|0.0|4011|mmu:20185|nuclear receptor co-repressor 1 GO:0070822//Sin3-type complex;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0070822//Sin3-type complex;GO:0005819//spindle;GO:0044444//cytoplasmic part GO:0030234//enzyme regulator activity;GO:0042974//retinoic acid receptor binding;GO:0035258//steroid hormone receptor binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0044212//transcription regulatory region DNA binding;GO:0019899//enzyme binding;GO:0030234//enzyme regulator activity;GO:0042974//retinoic acid receptor binding;GO:0035258//steroid hormone receptor binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0044212//transcription regulatory region DNA binding;GO:0019899//enzyme binding "GO:0006461//protein complex assembly;GO:0022037//metencephalon development;GO:0014706//striated muscle tissue development;GO:0055092//sterol homeostasis;GO:0035264//multicellular organism growth;GO:0007589//body fluid secretion;GO:0021536//diencephalon development;GO:0007254//JNK cascade;GO:0016575//histone deacetylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009968//negative regulation of signal transduction;GO:0008283//cell proliferation;GO:0007623//circadian rhythm;GO:0030218//erythrocyte differentiation;GO:0043367//CD4-positive, alpha-beta T cell differentiation;GO:0006461//protein complex assembly;GO:0022037//metencephalon development;GO:0014706//striated muscle tissue development;GO:0055092//sterol homeostasis;GO:0035264//multicellular organism growth;GO:0007589//body fluid secretion;GO:0021536//diencephalon development;GO:0007254//JNK cascade;GO:0016575//histone deacetylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009968//negative regulation of signal transduction;GO:0008283//cell proliferation;GO:0007623//circadian rhythm;GO:0030218//erythrocyte differentiation;GO:0043367//CD4-positive, alpha-beta T cell differentiation" gi|568972489|ref|XP_006532689.1|/8.63209e-122/PREDICTED: nuclear receptor corepressor 1 isoform X14 [Mus musculus] 18555 3128.18 79.89666667 82.44 0.045209191 Up 0.178184588 Cdk16 cyclin-dependent kinase 16 K08820|1|0.0|928|ocu:100349860|cyclin-dependent kinase 16 [EC:2.7.11.22] GO:0042995//cell projection;GO:0030136//clathrin-coated vesicle;GO:0009898//cytoplasmic side of plasma membrane GO:0032550;GO:0004674//protein serine/threonine kinase activity GO:0050796//regulation of insulin secretion;GO:0006796//phosphate-containing compound metabolic process;GO:0016192//vesicle-mediated transport;GO:0030030//cell projection organization;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006464//cellular protein modification process gi|655875601|ref|XP_008270766.1|/0/PREDICTED: cyclin-dependent kinase 16 isoform X5 [Oryctolagus cuniculus] 664799 3217 0.463333333 0.58 0.324002423 Up 0.178081161 Ctcfl CCCTC-binding factor (zinc finger protein)-like K09228|1|1e-63|247|sko:100378762|KRAB domain-containing zinc finger protein - - - - 26894 1727.75 69.80333333 72.25333333 0.049768215 Up 0.178043552 Cops7a COP9 signalosome subunit 7A K12180|1|3e-132|474|rno:312710|COP9 signalosome complex subunit 7 - - - - 101943 4299 19.46333333 18.71666667 -0.056435289 Down 0.17799654 Sf3b3 "splicing factor 3b, subunit 3" K12830|1|0.0|2402|cge:100752512|splicing factor 3B subunit 3 GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen GO:0097159//organic cyclic compound binding GO:0000377;GO:0065003 gi|19527174|ref|NP_598714.1|/0/splicing factor 3B subunit 3 [Mus musculus] 66977 2405 0.43 0.323333333 -0.411314413 Down 0.17795893 Nuf2 "NUF2, NDC80 kinetochore complex component" K11548|1|0.0|849|mmu:66977|kinetochore protein Nuf2 GO:0000776//kinetochore;GO:0043231//intracellular membrane-bounded organelle - GO:0007059//chromosome segregation;GO:0000087//mitotic M phase gi|110625714|ref|NP_075773.2|/0/kinetochore protein Nuf2 [Mus musculus] 244667 2408 0.456666667 0.346666667 -0.397592365 Down 0.17795893 Disc1 disrupted in schizophrenia 1 K16534|1|0.0|1471|mmu:244667|disrupted in schizophrenia 1 protein - - - gi|119874421|ref|NP_777279.2|/0/disrupted in schizophrenia 1 homolog isoform 1 [Mus musculus] 237436 5760 0.33 0.436666667 0.404066381 Up 0.17795893 Gas2l3 growth arrest-specific 2 like 3 K10382|1|4e-11|74.3|tca:662585|dystonin;K19827|2|4e-10|70.9|acs:103281665|microtuble-actin crosslinking factor 1 GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0005856//cytoskeleton GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0007010//cytoskeleton organization;GO:0022402//cell cycle process;GO:0007010//cytoskeleton organization;GO:0022402//cell cycle process;GO:0007010//cytoskeleton organization;GO:0022402//cell cycle process gi|547234822|ref|NP_001271273.1|/0/GAS2-like protein 3 isoform 2 [Mus musculus] 28169 3439 70.49333333 72.88 0.048036133 Up 0.177874309 Agpat3 1-acylglycerol-3-phosphate O-acyltransferase 3 K13523|1|0.0|769|mmu:28169|lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0016740//transferase activity GO:0006644//phospholipid metabolic process "gi|148699794|gb|EDL31741.1|/0/1-acylglycerol-3-phosphate O-acyltransferase 3, isoform CRA_b, partial [Mus musculus]" 399510 4490 5.263333333 5.59 0.086871518 Up 0.177864907 Map4k5 mitogen-activated protein kinase kinase kinase kinase 5 K08833|1|0.0|1620|mmu:399510|mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1] GO:0044424;GO:0016020//membrane GO:0032550;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity GO:0035556//intracellular signal transduction;GO:0006464//cellular protein modification process "gi|148704648|gb|EDL36595.1|/0/mitogen-activated protein kinase kinase kinase kinase 5, isoform CRA_c, partial [Mus musculus]" 170765 1554 5.073333333 5.403333333 0.090915732 Up 0.177864907 Ripply3 ripply transcriptional repressor 3 - GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0043009//chordate embryonic development gi|172073173|ref|NP_573492.2|/4.29994e-67/protein ripply3 [Mus musculus] 67454 1754.21 5.256666667 5.586666667 0.087839489 Up 0.177864907 Ikbip IKBKB interacting protein K10352|1|3e-11|72.4|cjo:107322050|myosin heavy chain;K17751|3|8e-10|67.4|amj:102573748|myosin heavy chain 6/7 GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0012502//induction of programmed cell death;GO:0010212//response to ionizing radiation;GO:0012502//induction of programmed cell death;GO:0010212//response to ionizing radiation gi|121583481|ref|NP_080442.2|/0/inhibitor of nuclear factor kappa-B kinase-interacting protein isoform 1 [Mus musculus] 13194 4171 67.48333333 65.15333333 -0.050692246 Down 0.177686261 Ddb1 damage specific DNA binding protein 1 K10610|1|0.0|2225|mmu:13194|DNA damage-binding protein 1 GO:0031981//nuclear lumen;GO:0080008//Cul4-RING E3 ubiquitin ligase complex GO:0003677//DNA binding GO:0006289//nucleotide-excision repair;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0022402//cell cycle process;GO:0016567//protein ubiquitination;GO:0007166//cell surface receptor signaling pathway gi|7657011|ref|NP_056550.1|/0/DNA damage-binding protein 1 [Mus musculus] 93684 1515 63.60333333 65.93333333 0.051905644 Up 0.177686261 15-Sep selenoprotein 15 - - - - - 14723 2732 0.806666667 0.95 0.235954872 Up 0.177667456 Gp1ba "glycoprotein 1b, alpha polypeptide" K06261|1|0.0|672|mmu:14723|platelet glycoprotein Ib alpha chain GO:0046658//anchored component of plasma membrane;GO:0016021//integral component of membrane - GO:0030195//negative regulation of blood coagulation;GO:0022610;GO:0032989 gi|2331240|gb|AAC53320.1|/0/platelet glycoprotein Ib-alpha [Mus musculus] 104252 1491 16.57 17.31333333 0.063309911 Up 0.177611042 Cdc42ep2 CDC42 effector protein (Rho GTPase binding) 2 - GO:0016020//membrane;GO:0005856//cytoskeleton GO:0005102//receptor binding;GO:0017048//Rho GTPase binding GO:0022604//regulation of cell morphogenesis;GO:0031269//pseudopodium assembly;GO:0030041//actin filament polymerization gi|22779864|ref|NP_081048.1|/4.91493e-105/cdc42 effector protein 2 [Mus musculus] 213012 1670.72 10.25333333 9.766666667 -0.070154839 Down 0.177611042 Abhd10 abhydrolase domain containing 10 K13702|1|1e-108|397|mmu:213012|abhydrolase domain-containing protein 10 [EC:3.1.1.93] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0016798//hydrolase activity, acting on glycosyl bonds" GO:0016139//glycoside catabolic process;GO:0016139//glycoside catabolic process;GO:0016139//glycoside catabolic process "gi|148665663|gb|EDK98079.1|/1.55091e-170/abhydrolase domain containing 10, isoform CRA_c [Mus musculus]" 72053 2276.91 17.36333333 16.62666667 -0.062544972 Down 0.177611042 Tmub2 transmembrane and ubiquitin-like domain containing 2 K08290|1|1e-09|68.2|gfr:102034598|Fas-activated serine/threonine kinase [EC:2.7.11.8] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|110625900|ref|NP_082352.1|/6.49055e-160/transmembrane and ubiquitin-like domain-containing protein 2 isoform 1 [Mus musculus] 11502 4057 10.48333333 9.99 -0.069540933 Down 0.177611042 Adam9 a disintegrin and metallopeptidase domain 9 (meltrin gamma) K06834|1|0.0|1526|mmu:11502|disintegrin and metalloproteinase domain-containing protein 9 [EC:3.4.24.-] - - - - 94254 2310 10.51 11 0.065740854 Up 0.177611042 Wbscr16 Williams-Beuren syndrome chromosome region 16 homolog (human) K10614|1|5e-25|119|acs:100563151|E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26] GO:0043231//intracellular membrane-bounded organelle - GO:0019222//regulation of metabolic process gi|15809010|ref|NP_291050.1|/0/Williams-Beuren syndrome chromosomal region 16 protein homolog [Mus musculus] 21976 3048.87 10.50333333 10.99 0.065344133 Up 0.177611042 Top3b topoisomerase (DNA) III beta K03165|1|0.0|1731|mmu:21976|DNA topoisomerase III [EC:5.99.1.2] - - - - 241274 4592 10.23 9.74 -0.070812468 Down 0.177611042 Pnpla7 patatin-like phospholipase domain containing 7 K14676|1|0.0|2594|mmu:241274|lysophospholipid hydrolase [EC:3.1.1.5] GO:0005740//mitochondrial envelope;GO:0005764//lysosome;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane GO:0003824//catalytic activity GO:0044238//primary metabolic process gi|74203836|dbj|BAE28519.1|/0/unnamed protein product [Mus musculus] 67437 2885 58.11333333 60.36333333 0.054803267 Up 0.177498214 Ssr3 "signal sequence receptor, gamma" K13251|1|4e-88|328|pale:102891115|translocon-associated protein subunit gamma GO:0071256;GO:0031227//intrinsic component of endoplasmic reticulum membrane - GO:0006612//protein targeting to membrane "gi|148683594|gb|EDL15541.1|/3.26678e-88/signal sequence receptor, gamma, isoform CRA_b, partial [Mus musculus]" 20018 963.04 63.74333333 65.96666667 0.049462743 Up 0.177451202 Polr1d polymerase (RNA) I polypeptide D K03020|1|6e-38|160|cfa:100686016|DNA-directed RNA polymerases I and III subunit RPAC2 GO:0044452//nucleolar part;GO:0044452//nucleolar part GO:0034062//RNA polymerase activity;GO:0005488//binding;GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity GO:0010467//gene expression;GO:0006383//transcription from RNA polymerase III promoter;GO:0006360//transcription from RNA polymerase I promoter gi|32189421|ref|NP_859419.1|/4.31031e-52/DNA-directed RNA polymerases I and III subunit RPAC2 isoform 2 [Mus musculus] 12490 2519.21 61.22 58.99666667 -0.053369601 Down 0.177451202 Cd34 CD34 antigen K06474|1|0.0|641|mmu:12490|CD34 antigen GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0044421;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0044421 GO:0005515//protein binding;GO:0043168//anion binding;GO:0005515//protein binding;GO:0043168//anion binding GO:0010467//gene expression;GO:0009888//tissue development;GO:0048534//hematopoietic or lymphoid organ development;GO:0050673//epithelial cell proliferation;GO:0006809//nitric oxide biosynthetic process;GO:0050710//negative regulation of cytokine secretion;GO:0007596//blood coagulation;GO:0070925//organelle assembly;GO:0042476//odontogenesis;GO:0001819//positive regulation of cytokine production;GO:0070265//necrotic cell death;GO:0050715//positive regulation of cytokine secretion;GO:0001570//vasculogenesis;GO:0009064//glutamine family amino acid metabolic process;GO:0007267//cell-cell signaling;GO:0007155//cell adhesion;GO:0001525//angiogenesis;GO:0006928//movement of cell or subcellular component;GO:0008015//blood circulation;GO:0001818//negative regulation of cytokine production;GO:0036301;GO:0072012//glomerulus vasculature development;GO:0097205//renal filtration;GO:0010467//gene expression;GO:0072008;GO:0048534//hematopoietic or lymphoid organ development;GO:0050673//epithelial cell proliferation;GO:0006809//nitric oxide biosynthetic process;GO:0050710//negative regulation of cytokine secretion;GO:0007596//blood coagulation;GO:0060055//angiogenesis involved in wound healing;GO:0070925//organelle assembly;GO:0042476//odontogenesis;GO:0001819//positive regulation of cytokine production;GO:0070265//necrotic cell death;GO:0050715//positive regulation of cytokine secretion;GO:0001570//vasculogenesis;GO:0009064//glutamine family amino acid metabolic process;GO:0007267//cell-cell signaling;GO:0007155//cell adhesion;GO:0006928//movement of cell or subcellular component;GO:0008015//blood circulation;GO:0001818//negative regulation of cytokine production;GO:0036301 gi|19526792|ref|NP_598415.1|/0/hematopoietic progenitor cell antigen CD34 isoform 2 precursor [Mus musculus] 59049 2294 1.316666667 1.49 0.178422178 Up 0.177422994 Slc22a17 "solute carrier family 22 (organic cation transporter), member 17" "K08213|1|2e-155|551|mmu:59049|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 17" GO:0031090//organelle membrane;GO:0016021//integral component of membrane GO:0038023//signaling receptor activity;GO:0005215//transporter activity GO:0015688//iron chelate transport;GO:0044763 "gi|743718738|ref|XP_010953114.1|/1.1177e-172/PREDICTED: solute carrier family 22 member 17, partial [Camelus bactrianus]" 270198 3377 1.286666667 1.46 0.182330022 Up 0.177422994 Pfkfb4 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4" "K19030|1|0.0|918|mmu:270198|6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 4 [EC:2.7.1.105 3.1.3.46]" GO:0044444//cytoplasmic part GO:0032550;GO:0008443//phosphofructokinase activity;GO:0050308//sugar-phosphatase activity GO:0006007//glucose catabolic process;GO:0044710;GO:0016310//phosphorylation "gi|568963872|ref|XP_006512196.1|/0/PREDICTED: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X1 [Mus musculus]" 19206 7318.32 1.416666667 1.25 -0.180572246 Down 0.177422994 Ptch1 patched 1 K06225|1|0.0|2550|mmu:19206|patched 1 - - - - 320940 5965 0.733333333 0.606666667 -0.273565073 Down 0.177338373 Atp11c "ATPase, class VI, type 11C" K01530|1|0.0|2056|mmu:320940|phospholipid-translocating ATPase [EC:3.6.3.1] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0003824//catalytic activity;GO:0032550;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0003824//catalytic activity GO:0006811//ion transport;GO:0006869//lipid transport;GO:0006811//ion transport;GO:0006869//lipid transport gi|49355804|ref|NP_001001798.1|/0/phospholipid-transporting ATPase 11C isoform b [Mus musculus] 235281 4173.09 0.243333333 0.343333333 0.496675968 Up 0.177310166 Scn3b "sodium channel, voltage-gated, type III, beta" K04847|1|7e-114|397|mmu:235281|voltage-gated sodium channel type III beta GO:0031674//I band;GO:0005887//integral component of plasma membrane;GO:0031674//I band;GO:0005887//integral component of plasma membrane;GO:0031674//I band;GO:0005887//integral component of plasma membrane GO:0005515//protein binding;GO:0005248//voltage-gated sodium channel activity;GO:0016247//channel regulator activity;GO:0005515//protein binding;GO:0005248//voltage-gated sodium channel activity;GO:0016247//channel regulator activity;GO:0005515//protein binding;GO:0005248//voltage-gated sodium channel activity;GO:0016247//channel regulator activity GO:0048731//system development;GO:0002027//regulation of heart rate;GO:0086010//membrane depolarization during action potential;GO:0007009//plasma membrane organization;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0003254//regulation of membrane depolarization;GO:0086065//cell communication involved in cardiac conduction;GO:0006935//chemotaxis;GO:0007600//sensory perception;GO:0034220//ion transmembrane transport;GO:0002028//regulation of sodium ion transport;GO:0048731//system development;GO:0002027//regulation of heart rate;GO:0086010//membrane depolarization during action potential;GO:0007009//plasma membrane organization;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0003254//regulation of membrane depolarization;GO:0086065//cell communication involved in cardiac conduction;GO:0006935//chemotaxis;GO:0007600//sensory perception;GO:0034220//ion transmembrane transport;GO:0002028//regulation of sodium ion transport;GO:0048731//system development;GO:0002027//regulation of heart rate;GO:0086010//membrane depolarization during action potential;GO:0007009//plasma membrane organization;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0003254//regulation of membrane depolarization;GO:0086065//cell communication involved in cardiac conduction;GO:0006935//chemotaxis;GO:0007600//sensory perception;GO:0034220//ion transmembrane transport;GO:0002028//regulation of sodium ion transport gi|50510815|dbj|BAD32393.1|/2.47187e-151/mKIAA1158 protein [Mus musculus] 69652 1831 0.35 0.246666667 -0.504792152 Down 0.177310166 2310069B03Rik RIKEN cDNA 2310069B03 gene - - - - "gi|148666624|gb|EDK99040.1|/4.38945e-45/mCG144868, partial [Mus musculus]" 94275 2752 62.18333333 64.36333333 0.04971109 Up 0.177310166 Maged1 "melanoma antigen, family D, 1" K12464|1|0.0|1251|mmu:94275|melanoma-associated antigen D1 GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part GO:0016909//SAP kinase activity;GO:0005488//binding GO:0051094//positive regulation of developmental process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0043405//regulation of MAP kinase activity gi|60360182|dbj|BAD90336.1|/0/mFLJ00163 protein [Mus musculus] 236915 5110.79 4.056666667 4.336666667 0.096291794 Up 0.177197337 Arhgef9 CDC42 guanine nucleotide exchange factor (GEF) 9 K05769|1|0.0|665|fab:101809410|Rho guanine nucleotide exchange factor 4 - - - - 217734 5082 4.053333333 3.77 -0.104544299 Down 0.177197337 Pomt2 protein-O-mannosyltransferase 2 K00728|1|0.0|1595|mmu:217734|dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109] - - - - 22031 7102.51 3.74 4.016666667 0.102960471 Up 0.177197337 Traf3 TNF receptor-associated factor 3 K03174|1|0.0|1157|mmu:22031|TNF receptor-associated factor 3 GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0019900//kinase binding;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0019900//kinase binding GO:0006915//apoptotic process;GO:0002697;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0019221//cytokine-mediated signaling pathway;GO:0032479//regulation of type I interferon production;GO:0032446//protein modification by small protein conjugation;GO:0002221//pattern recognition receptor signaling pathway;GO:0006508//proteolysis;GO:0006915//apoptotic process;GO:0002697;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0019221//cytokine-mediated signaling pathway;GO:0032479//regulation of type I interferon production;GO:0032446//protein modification by small protein conjugation;GO:0002221//pattern recognition receptor signaling pathway;GO:0006508//proteolysis gi|554894323|ref|NP_001273051.1|/0/TNF receptor-associated factor 3 isoform b [Mus musculus] 269713 4908 4.136666667 3.853333333 -0.102361718 Down 0.177197337 Clip2 CAP-GLY domain containing linker protein 2 K10422|1|0.0|1833|mmu:269713|CAP-Gly domain-containing linker protein 2 GO:0030141//secretory granule;GO:0043005//neuron projection;GO:0005874//microtubule;GO:0030141//secretory granule;GO:0043005//neuron projection;GO:0005874//microtubule GO:0008017//microtubule binding;GO:0008017//microtubule binding GO:0007019//microtubule depolymerization;GO:0007019//microtubule depolymerization "gi|148687480|gb|EDL19427.1|/0/cytoplasmic linker 2, isoform CRA_b, partial [Mus musculus]" 14886 4383.51 66.95666667 64.80333333 -0.047159683 Down 0.177178532 Gtf2i general transcription factor II I K03121|1|0.0|1882|mmu:14886|transcription initiation factor TFII-I GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0031981//nuclear lumen;GO:0044297//cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body GO:0019901//protein kinase binding;GO:0003676//nucleic acid binding;GO:0019901//protein kinase binding;GO:0019901//protein kinase binding;GO:0019901//protein kinase binding;GO:0019901//protein kinase binding "GO:0001525//angiogenesis;GO:0006351//transcription, DNA-templated;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0001525//angiogenesis;GO:0006351//transcription, DNA-templated;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0001525//angiogenesis;GO:0006351//transcription, DNA-templated;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0001525//angiogenesis;GO:0006351//transcription, DNA-templated;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0001525//angiogenesis;GO:0006351//transcription, DNA-templated;GO:0051480//regulation of cytosolic calcium ion concentration" "gi|148687503|gb|EDL19450.1|/0/general transcription factor II I, isoform CRA_g, partial [Mus musculus]" 108671 1631 7.12 7.503333333 0.07565441 Up 0.177178532 Dnajc9 DnaJ heat shock protein family (Hsp40) member C9 K09529|1|3e-134|481|mmu:108671|DnaJ homolog subfamily C member 9 - - - - 13506 4641.76 6.75 7.133333333 0.079688889 Up 0.177178532 Dsc2 desmocollin 2 K07601|1|0.0|1686|mmu:13506|desmocollin 2 - - - - 231717 2335 6.49 6.873333333 0.082791449 Up 0.177178532 Fam109a "family with sequence similarity 109, member A" K04349|1|9e-11|71.6|aec:105147142|Ras-specific guanine nucleotide-releasing factor 1 GO:0005768//endosome;GO:0030135//coated vesicle GO:0042802//identical protein binding;GO:0008289//lipid binding GO:0016192//vesicle-mediated transport;GO:0023051//regulation of signaling;GO:0006996//organelle organization gi|30425218|ref|NP_780683.1|/4.45937e-117/sesquipedalian-1 [Mus musculus] 75786 6584 7.043333333 7.426666667 0.076456465 Up 0.177178532 Ckap5 cytoskeleton associated protein 5 K16803|1|0.0|3650|mmu:75786|cytoskeleton-associated protein 5 GO:0005815//microtubule organizing center;GO:0032991//macromolecular complex;GO:0005815//microtubule organizing center;GO:0032991//macromolecular complex GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0031023//microtubule organizing center organization;GO:0000087//mitotic M phase;GO:0031023//microtubule organizing center organization;GO:0000087//mitotic M phase gi|260166721|ref|NP_001159461.1|/0/cytoskeleton-associated protein 5 isoform 1 [Mus musculus] 77480 7402 6.676666667 6.296666667 -0.084539719 Down 0.177178532 Kidins220 kinase D-interacting substrate 220 K12460|1|0.0|3213|mmu:77480|ankyrin repeat-rich membrane spanning protein - - - gi|124487039|ref|NP_001074847.1|/0/kinase D-interacting substrate of 220 kDa [Mus musculus] 11842 3481 15.65 16.37 0.064891665 Up 0.177084509 Arf3 ADP-ribosylation factor 3 K07938|1|3e-104|382|umr:103677912|ADP-ribosylation factor 3 GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0044444//cytoplasmic part GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0006810//transport;GO:0046474//glycerophospholipid biosynthetic process;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction gi|432114501|gb|ELK36349.1|/1.47661e-106/ADP-ribosylation factor 3 [Myotis davidii] 56044 2662 17.70333333 16.98666667 -0.059618252 Down 0.177084509 Rala v-ral simian leukemia viral oncogene A (ras related) K07834|1|1e-103|380|tup:102481337|Ras-related protein Ral-A "GO:0016020//membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0032155" GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0031753 GO:0042221//response to chemical;GO:0031346//positive regulation of cell projection organization;GO:0006887//exocytosis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0007264//small GTPase mediated signal transduction;GO:0051668//localization within membrane;GO:0009154//purine ribonucleotide catabolic process gi|562826833|ref|XP_006143062.1|/1.2463e-102/PREDICTED: ras-related protein Ral-A isoform X1 [Tupaia chinensis] 218203 2983 16.45 17.17333333 0.062082509 Up 0.177084509 Mylip myosin regulatory light chain interacting protein K10637|1|0.0|796|mmu:218203|E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27] - - - - 436090 1981 0.246666667 0.346666667 0.490986353 Up 0.176962278 Gpr62 G protein-coupled receptor 62 K08415|1|5e-82|308|mmu:436090|G protein-coupled receptor 62 - - - gi|227497579|ref|NP_001153124.1|/4.20179e-81/probable G-protein coupled receptor 62 [Mus musculus] 28035 2237 9.193333333 9.676666667 0.073922115 Up 0.176943473 Usp39 ubiquitin specific peptidase 39 K12847|1|0.0|1047|mmu:28035|U4/U6.U5 tri-snRNP-associated protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding "GO:0044763;GO:0000398//mRNA splicing, via spliceosome;GO:0019941//modification-dependent protein catabolic process" gi|20070404|ref|NP_613058.1|/0/U4/U6.U5 tri-snRNP-associated protein 2 [Mus musculus] 73666 2326 10.35 10.83 0.065402475 Up 0.176943473 Thoc3 THO complex 3 K12880|1|0.0|736|mmu:73666|THO complex subunit 3 - - - - 338366 6933 9.323333333 9.806666667 0.072916993 Up 0.176943473 Mia3 melanoma inhibitory activity 3 K17482|1|9e-31|139|ecb:100073259|spermatogenic leucine zipper protein 1 - - - - 100038654 1411 0.143333333 0.23 0.682259702 Up 0.176943473 Gm10371 predicted gene 10371 - - - - - 27225 2911.86 56.76666667 54.68666667 -0.053854901 Down 0.176924668 Ddx24 DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 K14805|1|0.0|1432|mmu:27225|ATP-dependent RNA helicase DDX24/MAK5 [EC:3.6.4.13] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550" - "gi|148686887|gb|EDL18834.1|/0/DEAD (Asp-Glu-Ala-Asp) box polypeptide 24, isoform CRA_a, partial [Mus musculus]" 100504231 1766 0.37 0.48 0.375509135 Up 0.176896461 Gm15708 predicted gene 15708 - - - - - 544696 7269 0.456666667 0.35 -0.383786565 Down 0.176896461 Tbc1d32 "TBC1 domain family, member 32" - - - - - 73692 10551 0.656666667 0.786666667 0.26059123 Up 0.176840047 2410089E03Rik RIKEN cDNA 2410089E03 gene - - - - - 12270 754 0.81 0.676666667 -0.259476586 Down 0.176840047 C4bp-ps1 "complement component 4 binding protein, pseudogene 1" "K04003|1|5e-31|136|rno:24236|complement component 4 binding protein, beta" - - GO:0006952//defense response;GO:0002455//humoral immune response mediated by circulating immunoglobulin gi|532009096|ref|XP_005348365.1|/4.46823e-31/PREDICTED: C4b-binding protein beta chain [Microtus ochrogaster] 74481 1433 1.123333333 1.28 0.18835772 Up 0.176830644 Batf2 "basic leucine zipper transcription factor, ATF-like 2" K09034|1|2e-132|475|mmu:74481|ATF-like basic leucine zipper transcriptional factor GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0048869//cellular developmental process;GO:0001562//response to protozoan;GO:0001773//myeloid dendritic cell activation;GO:0006351//transcription, DNA-templated" gi|28077033|ref|NP_083243.1|/1.29781e-131/basic leucine zipper transcriptional factor ATF-like 2 [Mus musculus] 12753 9665.63 2.593333333 2.826666667 0.12429411 Up 0.176811839 Clock circadian locomotor output cycles kaput K02223|1|0.0|1353|mmu:12753|circadian locomoter output cycles kaput protein [EC:2.3.1.48] - - - - 14571 5645.22 2.816666667 2.586666667 -0.122894689 Down 0.176811839 Gpd2 "glycerol phosphate dehydrogenase 2, mitochondrial" K00111|1|0.0|1356|mmu:14571|glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0019866//organelle inner membrane GO:0052590//sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity;GO:0046872//metal ion binding;GO:0052590//sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity;GO:0046872//metal ion binding GO:0006071//glycerol metabolic process;GO:0052646;GO:0019674//NAD metabolic process;GO:0006006//glucose metabolic process;GO:0006071//glycerol metabolic process;GO:0052646;GO:0019674//NAD metabolic process;GO:0006006//glucose metabolic process "gi|224922803|ref|NP_034404.3|/0/glycerol-3-phosphate dehydrogenase, mitochondrial precursor [Mus musculus]" 320742 1795 2.736666667 2.97 0.11804321 Up 0.176811839 A230072C01Rik RIKEN cDNA A230072C01 gene - GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - GO:0032446//protein modification by small protein conjugation;GO:0032446//protein modification by small protein conjugation "gi|148668405|gb|EDL00729.1|/4.57105e-38/mCG117709, isoform CRA_a [Mus musculus]" 16404 4035 56.94666667 58.99 0.050859012 Up 0.176811839 Itga7 integrin alpha 7 K06583|1|0.0|2160|mmu:16404|integrin alpha 7 GO:0044424;GO:0005887//integral component of plasma membrane GO:0043169//cation binding;GO:0046983//protein dimerization activity GO:0022610;GO:0022604//regulation of cell morphogenesis;GO:0048870//cell motility;GO:0007166//cell surface receptor signaling pathway;GO:0014706//striated muscle tissue development;GO:0001568//blood vessel development gi|112293269|ref|NP_032424.2|/0/integrin alpha-7 [Mus musculus] 217026 5677 2.803333333 2.576666667 -0.121637386 Down 0.176811839 Heatr6 HEAT repeat containing 6 - - - - gi|124249080|ref|NP_663407.2|/0/HEAT repeat-containing protein 6 [Mus musculus] 71909 2201 2.64 2.873333333 0.122187439 Up 0.176811839 Haus5 "HAUS augmin-like complex, subunit 5" K16588|1|0.0|1059|mmu:71909|HAUS augmin-like complex subunit 5 GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex - GO:0006461//protein complex assembly;GO:0031023//microtubule organizing center organization;GO:0000087//mitotic M phase "gi|57242949|gb|AAH89002.1|/0/2310022K01Rik protein, partial [Mus musculus]" 17216 3381 2.82 2.593333333 -0.120887508 Down 0.176811839 Mcm2 minichromosome maintenance complex component 2 K02540|1|0.0|1631|mmu:17216|DNA replication licensing factor MCM2 [EC:3.6.4.12] GO:0000808//origin recognition complex;GO:0031981//nuclear lumen GO:0043169//cation binding;GO:0032550;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0004386//helicase activity GO:0044772//mitotic cell cycle phase transition;GO:0006261//DNA-dependent DNA replication;GO:0051320;GO:0070670//response to interleukin-4;GO:0034728//nucleosome organization gi|74226965|dbj|BAE27124.1|/0/unnamed protein product [Mus musculus] 66997 1723 55.71333333 53.71333333 -0.05274238 Down 0.176689608 Psmd12 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 12" K03035|1|0.0|889|mmu:66997|26S proteasome regulatory subunit N5 GO:0022624//proteasome accessory complex - GO:0006511//ubiquitin-dependent protein catabolic process gi|511849661|ref|XP_004749181.1|/0/PREDICTED: 26S proteasome non-ATPase regulatory subunit 12 [Mustela putorius furo] 70408 4160 3.26 3.013333333 -0.113511693 Down 0.176623792 Polr3f polymerase (RNA) III (DNA directed) polypeptide F K03025|1|2e-180|636|rno:311487|DNA-directed RNA polymerase III subunit RPC6 GO:0044451 GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity GO:0006383//transcription from RNA polymerase III promoter;GO:0031349//positive regulation of defense response;GO:0032481//positive regulation of type I interferon production;GO:0002252 gi|157821329|ref|NP_001101254.1|/1.59605e-179/DNA-directed RNA polymerase III subunit RPC6 [Rattus norvegicus] 238037 2569.01 3.293333333 3.043333333 -0.113896182 Down 0.176623792 BC068281 cDNA sequence BC068281 K01262|1|5e-15|86.3|sko:102801971|Xaa-Pro aminopeptidase [EC:3.4.11.9] - - - gi|283046769|ref|NP_775592.2|/0/WD repeat and coiled-coil-containing protein C2orf44 homolog isoform 2 [Mus musculus] 269536 3203 3.293333333 3.043333333 -0.113896182 Down 0.176623792 Tex10 testis expressed gene 10 K14827|1|0.0|1724|mmu:269536|pre-rRNA-processing protein IPI1 GO:0044665//MLL1/2 complex;GO:0031224//intrinsic component of membrane - - gi|124249335|ref|NP_758508.2|/0/testis-expressed sequence 10 protein [Mus musculus] 14420 3826 3.31 3.06 -0.113299564 Down 0.176623792 Galc galactosylceramidase K01202|1|0.0|1363|mmu:14420|galactosylceramidase [EC:3.2.1.46] GO:0000323//lytic vacuole "GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds" GO:0006681//galactosylceramide metabolic process gi|93102411|ref|NP_032105.2|/0/galactocerebrosidase precursor [Mus musculus] 78781 3582.36 3.55 3.3 -0.105353 Down 0.176623792 Zc3hav1 "zinc finger CCCH type, antiviral 1" K15259|1|0.0|1859|mmu:78781|poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30] GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0019899//enzyme binding;GO:0016763//transferase activity, transferring pentosyl groups;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0019899//enzyme binding;GO:0016763//transferase activity, transferring pentosyl groups" GO:0043462//regulation of ATPase activity;GO:0032481//positive regulation of type I interferon production;GO:0019079//viral genome replication;GO:0006402//mRNA catabolic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0050688//regulation of defense response to virus;GO:0002684//positive regulation of immune system process;GO:0043330//response to exogenous dsRNA;GO:0043462//regulation of ATPase activity;GO:0032481//positive regulation of type I interferon production;GO:0019079//viral genome replication;GO:0006402//mRNA catabolic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0050688//regulation of defense response to virus;GO:0002684//positive regulation of immune system process;GO:0043330//response to exogenous dsRNA gi|21746169|ref|NP_083140.1|/0/zinc finger CCCH-type antiviral protein 1 isoform 2 [Mus musculus] 57915 5063.84 3.243333333 2.996666667 -0.114118689 Down 0.176623792 Tbc1d1 "TBC1 domain family, member 1" K18341|1|0.0|1988|ptr:461163|TBC1 domain family member 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0008104//protein localization;GO:0008104//protein localization gi|120587003|ref|NP_062610.2|/0/TBC1 domain family member 1 isoform 1 [Mus musculus] 100504586 3459 5.463333333 5.146666667 -0.086143102 Down 0.176567377 Gm20300 "predicted gene, 20300" - - - - gi|2193870|dbj|BAA20419.1|/5.38356e-58/reverse transcriptase [Mus musculus] 223701 4365.36 5.093333333 5.41 0.087018457 Up 0.176567377 Mkl1 MKL (megakaryoblastic leukemia)/myocardin-like 1 - GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003712//transcription cofactor activity;GO:0030275//LRR domain binding;GO:0097159//organic cyclic compound binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003779//actin binding;GO:0003712//transcription cofactor activity;GO:0030275//LRR domain binding;GO:0097159//organic cyclic compound binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003779//actin binding GO:0042692//muscle cell differentiation;GO:0006915//apoptotic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0042692//muscle cell differentiation;GO:0006915//apoptotic process;GO:0006366//transcription from RNA polymerase II promoter gi|127138894|ref|NP_694629.2|/0/MKL/myocardin-like protein 1 isoform 1 [Mus musculus] 67345 4019 5.62 5.296666667 -0.085485412 Down 0.176567377 Herc4 hect domain and RLD 4 K10615|1|0.0|2058|mmu:67345|E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26] - - - "gi|148700105|gb|EDL32052.1|/0/hect domain and RLD 4, isoform CRA_b, partial [Mus musculus]" 73010 4587 1.836666667 1.65 -0.154623794 Down 0.176492158 Gpr22 G protein-coupled receptor 22 K04319|1|0.0|812|mmu:73010|G protein-coupled receptor 22 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|26339128|dbj|BAC33235.1|/0/unnamed protein product [Mus musculus] 66536 1507 1.706666667 1.9 0.154818109 Up 0.176492158 Nipsnap3b nipsnap homolog 3B (C. elegans) K19269|1|2e-11|73.2|cbr:CBG06913|phosphoglycolate phosphatase [EC:3.1.3.18 3.1.3.48];K02D10.1;|2|3e-11|72.4|cel:CELE_K02D10.1|Putative NipSnap protein K02D10.1 GO:0043231//intracellular membrane-bounded organelle - - gi|13385084|ref|NP_079899.1|/5.46353e-144/protein NipSnap homolog 3B [Mus musculus] 229011 2208 1.906666667 1.72 -0.148644081 Down 0.176492158 Samd10 sterile alpha motif domain containing 10 - - - - "gi|148675490|gb|EDL07437.1|/1.42772e-117/sterile alpha motif domain containing 10, isoform CRA_c [Mus musculus]" 64050 1418 17.53333333 16.83 -0.059065122 Down 0.176473354 Yeats4 YEATS domain containing 4 K11341|1|1e-112|409|umr:103656875|YEATS domain-containing protein 4 GO:0034399//nuclear periphery;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0005198//structural molecule activity "GO:0040007//growth;GO:0000087//mitotic M phase;GO:0006351//transcription, DNA-templated;GO:0016573//histone acetylation" gi|13386064|ref|NP_080846.1|/1.12497e-111/YEATS domain-containing protein 4 [Mus musculus] 170743 3794 0.943333333 1.093333333 0.212893762 Up 0.176398135 Tlr7 toll-like receptor 7 K05404|1|0.0|1998|mmu:170743|toll-like receptor 7 GO:0045335//phagocytic vesicle;GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0045335//phagocytic vesicle;GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0045335//phagocytic vesicle;GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0045335//phagocytic vesicle;GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0045335//phagocytic vesicle;GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane GO:0038023//signaling receptor activity;GO:0003723//RNA binding;GO:0038023//signaling receptor activity;GO:0003723//RNA binding;GO:0038023//signaling receptor activity;GO:0003723//RNA binding;GO:0038023//signaling receptor activity;GO:0003723//RNA binding;GO:0038023//signaling receptor activity;GO:0003723//RNA binding GO:0052166;GO:0001774//microglial cell activation;GO:0042095//interferon-gamma biosynthetic process;GO:0002224//toll-like receptor signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0002252;GO:0006468//protein phosphorylation;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0052166;GO:0001774//microglial cell activation;GO:0042095//interferon-gamma biosynthetic process;GO:0002224//toll-like receptor signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0002252;GO:0006468//protein phosphorylation;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0052166;GO:0001774//microglial cell activation;GO:0042095//interferon-gamma biosynthetic process;GO:0002224//toll-like receptor signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0002252;GO:0006468//protein phosphorylation;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0052166;GO:0001774//microglial cell activation;GO:0042095//interferon-gamma biosynthetic process;GO:0002224//toll-like receptor signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0002252;GO:0006468//protein phosphorylation;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0052166;GO:0001774//microglial cell activation;GO:0042095//interferon-gamma biosynthetic process;GO:0002224//toll-like receptor signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0002252;GO:0006468//protein phosphorylation;GO:0042108//positive regulation of cytokine biosynthetic process gi|18875360|ref|NP_573474.1|/0/toll-like receptor 7 isoform a precursor [Mus musculus] 225182 3617.97 0.98 1.13 0.205469118 Up 0.176398135 Rbbp8 retinoblastoma binding protein 8 K02915|1|1e-08|65.1|hmg:100207460|large subunit ribosomal protein L34e;K11499|2|9e-06|55.8|cmk:103186168|centromere protein F GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001104//RNA polymerase II transcription cofactor activity;GO:0003677//DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0004520//endodeoxyribonuclease activity;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0003677//DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0004520//endodeoxyribonuclease activity;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0003677//DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0004520//endodeoxyribonuclease activity;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0003677//DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0004520//endodeoxyribonuclease activity GO:0006366//transcription from RNA polymerase II promoter;GO:0000725//recombinational repair;GO:0044772//mitotic cell cycle phase transition;GO:0001824//blastocyst development;GO:0000077//DNA damage checkpoint;GO:0000729//DNA double-strand break processing;GO:0000087//mitotic M phase;GO:0006366//transcription from RNA polymerase II promoter;GO:0000725//recombinational repair;GO:0044772//mitotic cell cycle phase transition;GO:0001824//blastocyst development;GO:0000077//DNA damage checkpoint;GO:0000729//DNA double-strand break processing;GO:0000087//mitotic M phase;GO:0006366//transcription from RNA polymerase II promoter;GO:0000725//recombinational repair;GO:0044772//mitotic cell cycle phase transition;GO:0001824//blastocyst development;GO:0000077//DNA damage checkpoint;GO:0000729//DNA double-strand break processing;GO:0000087//mitotic M phase;GO:0006366//transcription from RNA polymerase II promoter;GO:0000725//recombinational repair;GO:0044772//mitotic cell cycle phase transition;GO:0001824//blastocyst development;GO:0000077//DNA damage checkpoint;GO:0000729//DNA double-strand break processing;GO:0000087//mitotic M phase gi|124487005|ref|NP_001074692.1|/0/DNA endonuclease RBBP8 [Mus musculus] 73504 960 1.06 0.913333333 -0.214850872 Down 0.176398135 1700071M16Rik RIKEN cDNA 1700071M16 gene K01062|1|3e-15|84.7|mmu:27226|platelet-activating factor acetylhydrolase [EC:3.1.1.47] - - - - 22629 1806 51.87666667 49.96 -0.054312305 Down 0.176351123 Ywhah "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide" K16198|1|2e-135|485|ssc:100155504|14-3-3 protein gamma/eta GO:0044291//cell-cell contact zone;GO:0044424 GO:0016491//oxidoreductase activity;GO:0008092//cytoskeletal protein binding;GO:0016247//channel regulator activity;GO:0035258//steroid hormone receptor binding "GO:0006351//transcription, DNA-templated;GO:0015031//protein transport;GO:0006915//apoptotic process;GO:0007067//mitotic nuclear division;GO:0050804//modulation of synaptic transmission;GO:0006706//steroid catabolic process;GO:0002028//regulation of sodium ion transport;GO:0031345//negative regulation of cell projection organization;GO:0031958;GO:0030182//neuron differentiation" gi|6756037|ref|NP_035868.1|/1.71082e-134/14-3-3 protein eta [Mus musculus] 68347 825 10.33 9.863333333 -0.066693058 Down 0.176332318 0610011F06Rik methyltransferase like 26 "K19938|1|7e-31|136|phu:Phum_PHUM215280|rabphilin-3A;K15001|2|2e-19|98.6|api:100162179|cytochrome P450, family 4 [EC:1.14.-.-]" - - - gi|58037115|ref|NP_080962.1|/2.34963e-111/UPF0585 protein C16orf13 homolog [Mus musculus] 19289 3146 0.16 0.253333333 0.662965013 Up 0.176332318 Igdcc3 "immunoglobulin superfamily, DCC subclass, member 3" K06766|1|3e-69|266|sko:100329095|neogenin;K06765|3|9e-68|261|mdo:100010164|deleted in colorectal carcinoma GO:0031224//intrinsic component of membrane - GO:0050905//neuromuscular process gi|6679571|ref|NP_033014.1|/0/immunoglobulin superfamily DCC subclass member 3 [Mus musculus] 68730 1909 9.026666667 9.496666667 0.073227883 Up 0.176332318 Dus1l dihydrouridine synthase 1-like (S. cerevisiae) K05542|1|0.0|961|mmu:68730|tRNA-dihydrouridine synthase 1 [EC:1.3.1.88] - "GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0000166//nucleotide binding" GO:0006399//tRNA metabolic process;GO:0044710 gi|31980834|ref|NP_081100.2|/0/tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like [Mus musculus] 22778 5421 0.506666667 0.393333333 -0.365284464 Down 0.176275904 Ikzf1 IKAROS family zinc finger 1 K09220|1|0.0|845|rno:305501|IKAROS family zinc finger protein "GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043234//protein complex" GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding GO:0001865//NK T cell differentiation;GO:0030223//neutrophil differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043010//camera-type eye development;GO:0048537//mucosal-associated lymphoid tissue development;GO:0007420//brain development;GO:0035264//multicellular organism growth;GO:0006325//chromatin organization;GO:0001865//NK T cell differentiation;GO:0030223//neutrophil differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043010//camera-type eye development;GO:0048537//mucosal-associated lymphoid tissue development;GO:0007420//brain development;GO:0035264//multicellular organism growth;GO:0006325//chromatin organization;GO:0001865//NK T cell differentiation;GO:0030223//neutrophil differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043010//camera-type eye development;GO:0048537//mucosal-associated lymphoid tissue development;GO:0007420//brain development;GO:0035264//multicellular organism growth;GO:0006325//chromatin organization;GO:0001865//NK T cell differentiation;GO:0030223//neutrophil differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043010//camera-type eye development;GO:0048537//mucosal-associated lymphoid tissue development;GO:0007420//brain development;GO:0035264//multicellular organism growth;GO:0006325//chromatin organization;GO:0001865//NK T cell differentiation;GO:0030223//neutrophil differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043010//camera-type eye development;GO:0048537//mucosal-associated lymphoid tissue development;GO:0007420//brain development;GO:0035264//multicellular organism growth;GO:0006325//chromatin organization;GO:0001865//NK T cell differentiation;GO:0030223//neutrophil differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043010//camera-type eye development;GO:0048537//mucosal-associated lymphoid tissue development;GO:0007420//brain development;GO:0035264//multicellular organism growth;GO:0006325//chromatin organization gi|60359882|dbj|BAD90160.1|/0/mKIAA4227 protein [Mus musculus] 227627 738 0.486666667 0.376666667 -0.369645596 Down 0.176275904 Obp2a odorant binding protein 2A K01830|1|4e-06|53.9|shr:100913465|prostaglandin-H2 D-isomerase [EC:5.3.99.2] - - GO:0051234//establishment of localization gi|568913330|ref|XP_006497931.1|/2.37939e-90/PREDICTED: odorant-binding protein 2a isoform X1 [Mus musculus] 78894 3175 2.123333333 1.926666667 -0.14022388 Down 0.176228892 Aacs acetoacetyl-CoA synthetase K01907|1|0.0|1368|mmu:78894|acetoacetyl-CoA synthetase [EC:6.2.1.16] GO:0044444//cytoplasmic part GO:0016878//acid-thiol ligase activity;GO:0032550 GO:0010243//response to organonitrogen compound;GO:0070542//response to fatty acid;GO:0033574//response to testosterone;GO:0050796//regulation of insulin secretion;GO:0048513//animal organ development;GO:0045444//fat cell differentiation;GO:0044238//primary metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0036315//cellular response to sterol;GO:0044767//single-organism developmental process;GO:0006950//response to stress;GO:0001678//cellular glucose homeostasis;GO:0031667//response to nutrient levels gi|21313520|ref|NP_084486.1|/0/acetoacetyl-CoA synthetase [Mus musculus] 27414 1460 2.176666667 1.98 -0.136620061 Down 0.176228892 Sergef secretion regulating guanine nucleotide exchange factor K15421|1|0.0|973|mmu:27414|secretion-regulating guanine nucleotide exchange factor GO:0005856//cytoskeleton;GO:0031981//nuclear lumen - GO:0009306//protein secretion gi|7305093|ref|NP_038817.1|/0/secretion-regulating guanine nucleotide exchange factor [Mus musculus] 16568 5443.89 1.98 2.176666667 0.136620061 Up 0.176228892 Kif3a kinesin family member 3A K10394|1|0.0|1141|mmu:16568|kinesin family member 3A GO:0031513//nonmotile primary cilium;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005930//axoneme;GO:0030136//clathrin-coated vesicle;GO:0005871//kinesin complex;GO:0031513//nonmotile primary cilium;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005930//axoneme;GO:0030136//clathrin-coated vesicle;GO:0005871//kinesin complex;GO:0031513//nonmotile primary cilium;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005930//axoneme;GO:0030136//clathrin-coated vesicle;GO:0005871//kinesin complex GO:0032550;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0032550;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0032550;GO:0003774//motor activity;GO:0015631//tubulin binding GO:0007166//cell surface receptor signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:0006928//movement of cell or subcellular component;GO:0009855//determination of bilateral symmetry;GO:0043009//chordate embryonic development;GO:0048858//cell projection morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0010927;GO:0007166//cell surface receptor signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:0006928//movement of cell or subcellular component;GO:0009855//determination of bilateral symmetry;GO:0043009//chordate embryonic development;GO:0048858//cell projection morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0010927;GO:0007166//cell surface receptor signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:0006928//movement of cell or subcellular component;GO:0009855//determination of bilateral symmetry;GO:0043009//chordate embryonic development;GO:0048858//cell projection morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0010927 gi|940760818|ref|XP_014321037.1|/0/PREDICTED: kinesin-like protein KIF3A isoform X3 [Myotis lucifugus] 230909 1385 2.19 1.993333333 -0.135747886 Down 0.176228892 Gm572 predicted gene 572 - - - - gi|148227852|ref|NP_001078974.1|/0/uncharacterized protein C1orf127 homolog precursor [Mus musculus] 74253 2282 0.256666667 0.163333333 -0.652076697 Down 0.17618188 Klrg2 "killer cell lectin-like receptor subfamily G, member 2" K10072|1|6e-13|79.0|pss:102447265|C-type lectin domain family 2 member D;K06502|5|3e-12|76.6|gja:107115599|CD69 antigen GO:0031224//intrinsic component of membrane GO:0005488//binding - gi|119964698|ref|NP_001028343.2|/0/killer cell lectin-like receptor subfamily G member 2 [Mus musculus] 224703 1584.49 51.01666667 52.9 0.052299083 Up 0.176153673 2-Mar membrane-associated ring finger (C3HC4) 2 K10657|1|4e-142|508|umr:103681721|E3 ubiquitin-protein ligase MARCH2 [EC:2.3.2.27] GO:0031982//vesicle;GO:0005764//lysosome;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0031982//vesicle;GO:0005764//lysosome;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0031982//vesicle;GO:0005764//lysosome;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0031982//vesicle;GO:0005764//lysosome;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0016192//vesicle-mediated transport;GO:0032446//protein modification by small protein conjugation;GO:0016192//vesicle-mediated transport;GO:0032446//protein modification by small protein conjugation;GO:0016192//vesicle-mediated transport;GO:0032446//protein modification by small protein conjugation;GO:0016192//vesicle-mediated transport;GO:0032446//protein modification by small protein conjugation gi|31542053|ref|NP_663461.2|/9.83118e-169/E3 ubiquitin-protein ligase MARCH2 isoform 1 [Mus musculus] 20522 3009 0.513333333 0.636666667 0.310642287 Up 0.176134868 Slc23a1 "solute carrier family 23 (nucleobase transporters), member 1" "K14611|1|0.0|1169|mmu:20522|solute carrier family 23 (nucleobase transporter), member 1/2" GO:0016021//integral component of membrane;GO:0043226//organelle;GO:0042995//cell projection;GO:0016323//basolateral plasma membrane;GO:0044424 GO:0015370//solute:sodium symporter activity;GO:0051183//vitamin transporter activity;GO:0015145//monosaccharide transmembrane transporter activity GO:0006814//sodium ion transport;GO:0007417//central nervous system development;GO:0030323//respiratory tube development;GO:0015882//L-ascorbic acid transport;GO:0044763;GO:0042221//response to chemical gi|755560622|ref|XP_011245164.1|/0/PREDICTED: solute carrier family 23 member 1 isoform X1 [Mus musculus] 227835 2581 6.203333333 6.57 0.082849721 Up 0.176116063 Gtdc1 glycosyltransferase-like domain containing 1 - - GO:0016740//transferase activity GO:0008152//metabolic process "gi|148694915|gb|EDL26862.1|/0/glycosyltransferase-like domain containing 1, isoform CRA_d, partial [Mus musculus]" 171180 3277 6.296666667 6.67 0.083098466 Up 0.176116063 Syt12 synaptotagmin XII K19912|1|0.0|773|mmu:171180|synaptotagmin-12 GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle - GO:0007269//neurotransmitter secretion gi|19527400|ref|NP_598925.1|/0/synaptotagmin-12 [Mus musculus] 98432 6123 6.98 6.613333333 -0.077849417 Down 0.176116063 Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 K16340|1|0.0|2610|mmu:98432|PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16] - - - - 14783 4937.81 15.89666667 15.20666667 -0.064020336 Down 0.176087856 Grb10 growth factor receptor bound protein 10 K20064|1|0.0|1151|mmu:14783|growth factor receptor-bound protein 10 GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part "GO:0005102//receptor binding;GO:0030674//protein binding, bridging;GO:0008289//lipid binding;GO:0005102//receptor binding;GO:0030674//protein binding, bridging;GO:0008289//lipid binding" GO:0008286//insulin receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0010829//negative regulation of glucose transport;GO:0016310//phosphorylation;GO:0009967//positive regulation of signal transduction;GO:0005978//glycogen biosynthetic process;GO:0008286//insulin receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0010829//negative regulation of glucose transport;GO:0016310//phosphorylation;GO:0009967//positive regulation of signal transduction;GO:0005978//glycogen biosynthetic process gi|294979209|ref|NP_001171100.1|/0/growth factor receptor-bound protein 10 isoform 2 [Mus musculus] 74591 8323 0.253333333 0.353333333 0.479992941 Up 0.176059649 Abca12 "ATP-binding cassette, sub-family A (ABC1), member 12" "K05646|1|0.0|5073|mmu:74591|ATP-binding cassette, subfamily A (ABC1), member 12" - - - gi|225703056|ref|NP_780419.2|/0/ATP-binding cassette sub-family A member 12 [Mus musculus] 19260 2753 0.246666667 0.343333333 0.477047162 Up 0.176059649 Ptpn22 "protein tyrosine phosphatase, non-receptor type 22 (lymphoid)" K18024|1|0.0|1541|mmu:19260|tyrosine-protein phosphatase non-receptor type 12/18/22 [EC:3.1.3.48] GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044444//cytoplasmic part GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0004721//phosphoprotein phosphatase activity;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0004721//phosphoprotein phosphatase activity GO:0030098//lymphocyte differentiation;GO:0006470//protein dephosphorylation;GO:0042110//T cell activation;GO:0001787//natural killer cell proliferation;GO:0050852//T cell receptor signaling pathway;GO:0030098//lymphocyte differentiation;GO:0006470//protein dephosphorylation;GO:0042110//T cell activation;GO:0001787//natural killer cell proliferation;GO:0050852//T cell receptor signaling pathway gi|6679555|ref|NP_033005.1|/0/tyrosine-protein phosphatase non-receptor type 22 [Mus musculus] 18689 1391 0.253333333 0.35 0.466318004 Up 0.175965625 Phxr4 per-hexamer repeat gene 4 - - - - gi|76827447|gb|AAI07290.1|/8.55243e-40/Per-hexamer repeat gene 4 [Mus musculus] 112418 1113 0.266666667 0.37 0.472487771 Up 0.175965625 1700102P08Rik RIKEN cDNA 1700102P08 gene - - - - gi|568962743|ref|XP_006511691.1|/5.09378e-143/PREDICTED: uncharacterized protein C3orf62 homolog isoform X1 [Mus musculus] 100045469 2246.92 0.256666667 0.356666667 0.474680446 Up 0.175965625 Gm14204 predicted gene 14204 - GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0046872//metal ion binding GO:0032446//protein modification by small protein conjugation "gi|148674327|gb|EDL06274.1|/1.75713e-16/mCG141217, partial [Mus musculus]" 223697 3801.88 53.73333333 55.54333333 0.047796422 Up 0.175881003 Sun2 Sad1 and UNC84 domain containing 2 K19347|1|0.0|1197|mmu:223697|SUN domain-containing protein 1/2 "GO:0031224//intrinsic component of membrane;GO:0000228//nuclear chromosome;GO:0019866//organelle inner membrane;GO:0000781//chromosome, telomeric region;GO:0034992//microtubule organizing center attachment site;GO:0031224//intrinsic component of membrane;GO:0000228//nuclear chromosome;GO:0019866//organelle inner membrane;GO:0000781//chromosome, telomeric region;GO:0034992//microtubule organizing center attachment site;GO:0031224//intrinsic component of membrane;GO:0000228//nuclear chromosome;GO:0019866//organelle inner membrane;GO:0000781//chromosome, telomeric region;GO:0034992//microtubule organizing center attachment site" GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0016477//cell migration;GO:0007097//nuclear migration;GO:0007010//cytoskeleton organization;GO:0043578//nuclear matrix organization;GO:0016477//cell migration;GO:0007097//nuclear migration;GO:0007010//cytoskeleton organization;GO:0043578//nuclear matrix organization;GO:0016477//cell migration;GO:0007097//nuclear migration;GO:0007010//cytoskeleton organization;GO:0043578//nuclear matrix organization gi|329299037|ref|NP_001192275.1|/0/SUN domain-containing protein 2 isoform 2 [Mus musculus] 56210 4279 4.093333333 3.82 -0.099703517 Down 0.175796382 Rev1 "REV1, DNA directed polymerase" K03515|1|0.0|2335|mmu:56210|DNA repair protein REV1 [EC:2.7.7.-] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003677//DNA binding;GO:0034061//DNA polymerase activity GO:0019985//translesion synthesis;GO:0009416//response to light stimulus gi|40254551|ref|NP_062516.2|/0/DNA repair protein REV1 [Mus musculus] 75560 10753.98 3.99 3.716666667 -0.102379442 Down 0.175796382 Ep400 E1A binding protein p400 K11320|1|0.0|4099|mmu:75560|E1A-binding protein p400 [EC:3.6.4.-] GO:0016604//nuclear body;GO:0043189//H4/H2A histone acetyltransferase complex GO:0032550 GO:0016573//histone acetylation gi|153945880|ref|NP_083613.2|/0/E1A-binding protein p400 isoform 1 [Mus musculus] 18045 2552 3.963333333 3.696666667 -0.10048935 Down 0.175796382 Nfyb nuclear transcription factor-Y beta K08065|1|7e-121|437|cjo:107314769|nuclear transcription Y subunit beta GO:0005667//transcription factor complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity;GO:0008134//transcription factor binding "GO:0006351//transcription, DNA-templated" gi|26347857|dbj|BAC37577.1|/6.80951e-120/unnamed protein product [Mus musculus] 23802 3694 52.45 50.65666667 -0.050190626 Down 0.17578698 Amfr autocrine motility factor receptor K10636|1|0.0|1253|mmu:23802|autocrine motility factor receptor [EC:2.3.2.27] GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0044297//cell body;GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006461//protein complex assembly;GO:0016567//protein ubiquitination;GO:0006984//ER-nucleus signaling pathway gi|113205073|ref|NP_035917.2|/0/E3 ubiquitin-protein ligase AMFR [Mus musculus] 67452 4425 17.38 16.70333333 -0.057292045 Down 0.175721163 Pnpla8 patatin-like phospholipase domain containing 8 K16815|1|0.0|1530|mmu:67452|calcium-independent phospholipase A2-gamma GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0044439;GO:0012505//endomembrane system GO:0032550;GO:0004623//phospholipase A2 activity GO:0046470//phosphatidylcholine metabolic process;GO:0015909//long-chain fatty acid transport;GO:0001676//long-chain fatty acid metabolic process;GO:0006693//prostaglandin metabolic process;GO:0046337//phosphatidylethanolamine metabolic process;GO:0046164//alcohol catabolic process gi|12835918|dbj|BAB23417.1|/0/unnamed protein product [Mus musculus] 53413 3296.34 15.95333333 15.27666667 -0.062528111 Down 0.175721163 Exoc7 exocyst complex component 7 K07195|1|0.0|1297|mmu:53413|exocyst complex component 7 GO:0043234//protein complex;GO:0030426//growth cone;GO:0044444//cytoplasmic part;GO:0005813//centrosome;GO:0016020//membrane;GO:0030426//growth cone;GO:0005813//centrosome;GO:0016020//membrane GO:0005488//binding;GO:0005488//binding GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport gi|247269408|ref|NP_058553.2|/0/exocyst complex component 7 isoform 1 [Mus musculus] 67394 978 0.156666667 0.243333333 0.635235707 Up 0.175664749 4930404I05Rik RIKEN cDNA 4930404I05 gene - - - - "gi|148671894|gb|EDL03841.1|/1.10667e-55/mCG145892, partial [Mus musculus]" 100504728 2639 1.503333333 1.68 0.1602963 Up 0.175645944 Gm13985 predicted gene 13985 "K03847|1|2e-07|41.2|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - - 94220 4582 1.506666667 1.686666667 0.162814612 Up 0.175645944 Cnnm4 cyclin M4 K16302|1|0.0|1399|mmu:94220|metal transporter CNNM - - - - 15381 2803.91 46.27 48.02333333 0.053658447 Up 0.175645944 Hnrnpc heterogeneous nuclear ribonucleoprotein C K12884|1|1e-94|350|rno:100911576|heterogeneous nuclear ribonucleoprotein C1/C2 GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003723//RNA binding - gi|74218228|dbj|BAE31679.1|/1.54853e-114/unnamed protein product [Mus musculus] 12464 1966 48.60666667 46.85333333 -0.05300251 Down 0.175645944 Cct4 "chaperonin containing Tcp1, subunit 4 (delta)" K09496|1|0.0|1026|mmu:12464|T-complex protein 1 subunit delta GO:0005815//microtubule organizing center;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0048770 GO:0032550;GO:0005515//protein binding GO:0051084//'de novo' posttranslational protein folding;GO:0035036//sperm-egg recognition gi|6753322|ref|NP_033967.1|/0/T-complex protein 1 subunit delta [Mus musculus] 414085 2546 1.546666667 1.73 0.161609733 Up 0.175645944 9330151L19Rik RIKEN cDNA 9330151L19 gene "K19751|1|5e-91|230|aml:100473128|dynein assembly factor 2, axonemal" - - - - 77593 5874 1.71 1.533333333 -0.157324965 Down 0.175645944 Usp45 ubiquitin specific petidase 45 K11844|1|0.0|1585|mmu:77593|ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12] - "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019941//modification-dependent protein catabolic process;GO:0019941//modification-dependent protein catabolic process "gi|148673607|gb|EDL05554.1|/0/ubiquitin specific petidase 45, isoform CRA_b, partial [Mus musculus]" 100182 5392.36 2.163333333 2.37 0.131631082 Up 0.175636541 Akna AT-hook transcription factor - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|113865877|ref|NP_001038979.1|/0/AT-hook-containing transcription factor [Mus musculus] 101148 4147 2.386666667 2.18 -0.130668952 Down 0.175636541 B630005N14Rik base methyltransferase of 25S rRNA 2 - - - - - 66967 6550.01 2.356666667 2.15 -0.132411054 Down 0.175636541 Edem3 "ER degradation enhancer, mannosidase alpha-like 3" "K10086|1|0.0|1692|mmu:66967|ER degradation enhancer, mannosidase alpha-like 3" GO:0044432 GO:0046872//metal ion binding;GO:0015924//mannosyl-oligosaccharide mannosidase activity GO:0009100//glycoprotein metabolic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0035966//response to topologically incorrect protein gi|163310723|ref|NP_001034733.2|/0/ER degradation-enhancing alpha-mannosidase-like protein 3 isoform 1 precursor [Mus musculus] 65247 5772 2.47 2.26 -0.128188269 Down 0.175636541 Asb1 ankyrin repeat and SOCS box-containing 1 K10323|1|0.0|665|mmu:65247|ankyrin repeat and SOCS box protein 1 - - GO:0007165//signal transduction;GO:0046546//development of primary male sexual characteristics;GO:0007165//signal transduction;GO:0046546//development of primary male sexual characteristics gi|85060520|ref|NP_075533.3|/0/ankyrin repeat and SOCS box protein 1 isoform b [Mus musculus] 66390 1403 56.07666667 54.33333333 -0.045563036 Down 0.175617737 Slmo2 slowmo homolog 2 (Drosophila) - - - - - 76580 3947.49 9.456666667 9.92 0.069008376 Up 0.175608334 Mib2 mindbomb E3 ubiquitin protein ligase 2 K10645|1|0.0|1733|mmu:76580|E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27] GO:0005768//endosome;GO:0005768//endosome;GO:0005768//endosome GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0060089;GO:0019787//ubiquitin-like protein transferase activity;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0060089;GO:0019787//ubiquitin-like protein transferase activity;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0060089;GO:0019787//ubiquitin-like protein transferase activity GO:0032446//protein modification by small protein conjugation;GO:0007166//cell surface receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0032446//protein modification by small protein conjugation;GO:0007166//cell surface receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0032446//protein modification by small protein conjugation;GO:0007166//cell surface receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|110347531|ref|NP_660106.2|/0/E3 ubiquitin-protein ligase MIB2 isoform 2 [Mus musculus] 319675 7380 0.656666667 0.533333333 -0.300123725 Down 0.175580127 Cep295 centrosomal protein 295 K09188|1|5e-09|67.8|obi:106883022|histone-lysine N-methyltransferase MLL3 [EC:2.1.1.43];K14972|2|3e-07|62.0|der:Dere_GG13740|PAX-interacting protein 1;K16462|3|2e-06|58.9|mgp:100544522|centrosomal protein CEP164 - - - gi|161377458|ref|NP_795950.2|/0/centrosomal protein of 295 kDa [Mus musculus] 109129 1302 53.95333333 55.68333333 0.045533482 Up 0.175570725 Mmadhc "methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria" K15265|1|3e-25|118|smm:Smp_194510|21S rRNA pseudouridine2819 synthase [EC:5.4.99.43] GO:0043231//intracellular membrane-bounded organelle - GO:0006767//water-soluble vitamin metabolic process "gi|564340867|ref|XP_006234220.1|/2.67937e-165/PREDICTED: methylmalonic aciduria and homocystinuria type D homolog, mitochondrial isoform X1 [Rattus norvegicus]" 11532 1604 48.48333333 46.75333333 -0.052419663 Down 0.175570725 Adh5 "alcohol dehydrogenase 5 (class III), chi polypeptide" K00121|1|0.0|701|mmu:11532|S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0008289//lipid binding;GO:0036094//small molecule binding;GO:0004029//aldehyde dehydrogenase (NAD) activity;GO:0046914//transition metal ion binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0008289//lipid binding;GO:0036094//small molecule binding;GO:0004029//aldehyde dehydrogenase (NAD) activity" GO:0044282;GO:0008217//regulation of blood pressure;GO:0006067//ethanol metabolic process;GO:0044767//single-organism developmental process;GO:0016101//diterpenoid metabolic process;GO:0002237//response to molecule of bacterial origin;GO:0017014//protein nitrosylation;GO:0006950//response to stress;GO:0044282;GO:0008217//regulation of blood pressure;GO:0006067//ethanol metabolic process;GO:0044767//single-organism developmental process;GO:0016101//diterpenoid metabolic process;GO:0002237//response to molecule of bacterial origin;GO:0017014//protein nitrosylation;GO:0006950//response to stress gi|31982511|ref|NP_031436.2|/0/alcohol dehydrogenase class-3 isoform 1 [Mus musculus] 104346 1687 5.106666667 4.8 -0.089347486 Down 0.175401482 Gas8 growth arrest specific 8 K19942|1|0.0|825|mmu:104346|growth arrest-specific protein 8 GO:0005815//microtubule organizing center;GO:0005929//cilium GO:0017016//Ras GTPase binding GO:0048870//cell motility;GO:0008104//protein localization gi|1154620|gb|AAA85258.1|/0/growth-arrest-specific protein 8 [Mus musculus] 67074 9286.89 4.94 4.626666667 -0.09453788 Down 0.175401482 Mon2 "MON2 homolog, regulator of endosome to Golgi trafficking" K18466|1|2e-76|292|tsp:Tsp_03859|vacuolar protein sorting-associated protein 26;K18442|3|7e-15|87.4|tca:661541|brefeldin A-inhibited guanine nucleotide-exchange protein - - GO:0045184//establishment of protein localization;GO:0006810//transport;GO:0045184//establishment of protein localization;GO:0006810//transport;GO:0045184//establishment of protein localization;GO:0006810//transport gi|28972582|dbj|BAC65707.1|/0/mKIAA1040 protein [Mus musculus] 73914 2969 5.003333333 4.693333333 -0.092276643 Down 0.175401482 Irak3 interleukin-1 receptor-associated kinase 3 K04732|1|0.0|1213|mmu:73914|interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity GO:0006915//apoptotic process;GO:0043405//regulation of MAP kinase activity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0031348//negative regulation of defense response;GO:0043331//response to dsRNA;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0009895;GO:0002237//response to molecule of bacterial origin;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0043241//protein complex disassembly;GO:0002224//toll-like receptor signaling pathway;GO:0002719;GO:0002645//positive regulation of tolerance induction gi|31543005|ref|NP_082955.2|/0/interleukin-1 receptor-associated kinase 3 [Mus musculus] 20454 2278.78 46.58 48.28 0.051715037 Up 0.175392079 St3gal5 "ST3 beta-galactoside alpha-2,3-sialyltransferase 5" "K03370|1|0.0|769|mmu:20454|lactosylceramide alpha-2,3-sialyltransferase (sialyltransferase 9) [EC:2.4.99.9]" GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane GO:0008373//sialyltransferase activity;GO:0008373//sialyltransferase activity GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process "gi|568941230|ref|XP_006505879.1|/0/PREDICTED: lactosylceramide alpha-2,3-sialyltransferase isoform X2 [Mus musculus]" 69387 1172 0.253333333 0.163333333 -0.633217669 Down 0.175307458 Dnajb13 DnaJ heat shock protein family (Hsp40) member B13 K09519|1|0.0|655|mmu:69387|DnaJ homolog subfamily B member 13 - - - - 26901 588 50.64666667 52.29666667 0.046251673 Up 0.175138215 Deb1 differentially expressed in B16F10 1 K15623|1|4e-22|106|cmk:103188067|protein SSXT - - - "gi|148677194|gb|EDL09141.1|/2.44199e-45/differentially expressed in B16F10 1, isoform CRA_c [Mus musculus]" 57319 1791 48.04333333 49.69333333 0.048716067 Up 0.175138215 Smpdl3a "sphingomyelin phosphodiesterase, acid-like 3A" K01128|1|0.0|926|mmu:57319|sphingomyelin phosphodiesterase acid-like 3 [EC:3.1.4.-] GO:0044421 GO:0016787//hydrolase activity GO:0006684//sphingomyelin metabolic process gi|114431242|ref|NP_065586.3|/0/acid sphingomyelinase-like phosphodiesterase 3a precursor [Mus musculus] 238564 5641 50.80333333 52.44 0.045744527 Up 0.175091203 Mylk4 "myosin light chain kinase family, member 4" K00907|1|0.0|778|mmu:238564|myosin-light-chain kinase [EC:2.7.11.18] - - - gi|260447058|ref|NP_001159502.1|/0/myosin light chain kinase family member 4 [Mus musculus] 22088 1832 42.83666667 44.47666667 0.054202447 Up 0.175091203 Tsg101 tumor susceptibility gene 101 K12183|1|0.0|715|mmu:22088|ESCRT-I complex subunit TSG101 GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0005770//late endosome GO:0044389//ubiquitin-like protein ligase binding;GO:0003713//transcription coactivator activity "GO:0006351//transcription, DNA-templated;GO:0046753;GO:0040007//growth;GO:0008283//cell proliferation;GO:0009913//epidermal cell differentiation;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007041//lysosomal transport;GO:0016567//protein ubiquitination;GO:0022402//cell cycle process;GO:0045184//establishment of protein localization" gi|11230780|ref|NP_068684.1|/0/tumor susceptibility gene 101 protein [Mus musculus] 16490 11582 0.266666667 0.363333333 0.44625623 Up 0.175081801 Kcna2 "potassium voltage-gated channel, shaker-related subfamily, member 2" K04875|1|0.0|884|ngi:103747811|potassium voltage-gated channel Shaker-related subfamily A member 2 GO:0033267;GO:0005887//integral component of plasma membrane GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity GO:0051259//protein oligomerization;GO:0021604;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|25742772|ref|NP_037102.1|/0/potassium voltage-gated channel subfamily A member 2 [Rattus norvegicus] 76156 4048 0.363333333 0.266666667 -0.44625623 Down 0.175081801 Fam131b "family with sequence similarity 131, member B" K03260|1|1e-32|145|shr:100933156|translation initiation factor 4G - - - gi|568943124|ref|XP_006506793.1|/0/PREDICTED: protein FAM131B isoform X1 [Mus musculus] 213417 4269 6.71 6.35 -0.079556175 Down 0.175081801 Klhdc8a kelch domain containing 8A K10446|1|6e-25|119|mze:101488101|kelch-like protein 8;K10455|3|8e-25|119|tad:TRIADDRAFT_31047|kelch-like protein 18 - - - "gi|148707735|gb|EDL39682.1|/0/kelch domain containing 8A, isoform CRA_b, partial [Mus musculus]" 56325 3334 6.806666667 6.443333333 -0.079141229 Down 0.175081801 Abcb9 "ATP-binding cassette, sub-family B (MDR/TAP), member 9" "K05656|1|0.0|1489|mmu:56325|ATP-binding cassette, subfamily B (MDR/TAP), member 9" - - - gi|26006275|dbj|BAC41480.1|/0/mKIAA1520 protein [Mus musculus] 233887 2659 6.246666667 6.61 0.081563725 Up 0.175081801 Zfp553 zinc finger protein 553 K09228|1|3e-72|184|rno:100363065|KRAB domain-containing zinc finger protein GO:0005622//intracellular GO:0046872//metal ion binding "GO:0006351//transcription, DNA-templated" gi|22122757|ref|NP_666313.1|/0/zinc finger protein 48 [Mus musculus] 100169878 727 0.266666667 0.173333333 -0.621488377 Down 0.175072398 Gm10941 predicted gene 10941 - - - - - 100039805 1062 0.266666667 0.173333333 -0.621488377 Down 0.175072398 D5Ertd605e "DNA segment, Chr 5, ERATO Doi 605, expressed" - - - - gi|149034841|gb|EDL89561.1|/1.77554e-41/rCG63176 [Rattus norvegicus] 58805 3649 15.78333333 16.44333333 0.059100862 Up 0.175072398 Mlxipl MLX interacting protein-like K09113|1|0.0|1356|mmu:58805|MAX-like protein X - - - - 105732 4513 0.166666667 0.256666667 0.622930351 Up 0.175072398 Fam83h "family with sequence similarity 83, member H" K16805|1|2e-49|201|phi:102113873|protein FAM83D - - GO:0009888//tissue development;GO:0009888//tissue development "gi|148697565|gb|EDL29512.1|/0/expressed sequence AA409316, partial [Mus musculus]" 66111 1324 16.14 16.8 0.057820654 Up 0.175072398 Tmed3 transmembrane emp24 domain containing 3 K20350|1|2e-106|388|mmu:66111|p24 family protein gamma-4 GO:0000139//Golgi membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0030120//vesicle coat;GO:0031224//intrinsic component of membrane - GO:0045184//establishment of protein localization gi|12835786|dbj|BAB23361.1|/1.87088e-105/unnamed protein product [Mus musculus] 76920 1163 0.173333333 0.266666667 0.621488377 Up 0.175072398 Arrdc5 arrestin domain containing 5 - - - GO:0007154//cell communication gi|110626086|ref|NP_084075.1|/1.84369e-175/arrestin domain-containing protein 5 [Mus musculus] 22668 4267.42 44.39333333 46 0.051290822 Up 0.174903155 Sf1 splicing factor 1 K13095|1|3e-163|579|myd:102766758|splicing factor 1 GO:0031981//nuclear lumen;GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen;GO:0030529//intracellular ribonucleoprotein complex GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding GO:0007275//multicellular organism development;GO:0003006//developmental process involved in reproduction;GO:0006376//mRNA splice site selection;GO:0006694//steroid biosynthetic process;GO:0008285//negative regulation of cell proliferation;GO:0007049//cell cycle;GO:0012502//induction of programmed cell death;GO:0007049//cell cycle;GO:0008285//negative regulation of cell proliferation;GO:0006694//steroid biosynthetic process;GO:0007275//multicellular organism development;GO:0003006//developmental process involved in reproduction gi|569005760|ref|XP_006531797.1|/0/PREDICTED: splicing factor 1 isoform X2 [Mus musculus] 12268 5427 8.913333333 8.463333333 -0.07473907 Down 0.174893753 C4b complement component 4B (Chido blood group) K03989|1|0.0|3378|mmu:12268|complement component 4 GO:0044421 - GO:0019724//B cell mediated immunity gi|568998745|ref|XP_006523594.1|/0/PREDICTED: complement C4-B isoform X1 [Mus musculus] 73274 3610.41 8.98 8.533333333 -0.073606041 Down 0.174893753 Gpbp1 GC-rich promoter binding protein 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|171916092|ref|NP_001116435.1|/0/vasculin isoform 1 [Mus musculus] 21814 6074 9.566666667 9.12 -0.068982507 Down 0.174893753 Tgfbr3 "transforming growth factor, beta receptor III" "K05843|1|0.0|1643|mmu:21814|transforming growth factor, beta receptor III" GO:0009986//cell surface;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0044421;GO:0031012//extracellular matrix GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005539//glycosaminoglycan binding;GO:0005160//transforming growth factor beta receptor binding;GO:0032403//protein complex binding;GO:0019904//protein domain specific binding;GO:0019838//growth factor binding GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0003018;GO:0001701//in utero embryonic development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0034698//response to gonadotropin;GO:0001837//epithelial to mesenchymal transition;GO:0034694//response to prostaglandin;GO:0040007//growth;GO:0051098//regulation of binding;GO:0001570//vasculogenesis;GO:0008285//negative regulation of cell proliferation;GO:0010631//epithelial cell migration;GO:0035556//intracellular signal transduction;GO:0006464//cellular protein modification process;GO:0065003;GO:0006950//response to stress;GO:0030218//erythrocyte differentiation;GO:0014855;GO:0003208//cardiac ventricle morphogenesis gi|47271511|ref|NP_035708.2|/0/transforming growth factor beta receptor type 3 precursor [Mus musculus] 69064 2354.12 9.273333333 9.726666667 0.068857463 Up 0.174893753 Fuom fucose mutarotase K02431|1|1e-80|303|mmu:69064|L-fucose mutarotase [EC:5.1.3.29] - GO:0048029//monosaccharide binding;GO:0016854//racemase and epimerase activity;GO:0048029//monosaccharide binding;GO:0016854//racemase and epimerase activity;GO:0048029//monosaccharide binding;GO:0016854//racemase and epimerase activity;GO:0048029//monosaccharide binding;GO:0016854//racemase and epimerase activity GO:0019318//hexose metabolic process;GO:0019318//hexose metabolic process;GO:0019318//hexose metabolic process;GO:0019318//hexose metabolic process gi|555290089|ref|NP_001273146.1|/2.31529e-81/fucose mutarotase isoform 2 [Mus musculus] 13479 2249 46.24666667 47.85 0.049169541 Up 0.174856144 Dpep1 dipeptidase 1 (renal) K01273|1|0.0|745|mmu:13479|membrane dipeptidase [EC:3.4.13.19] - - - - 74167 1492 48.26333333 46.67666667 -0.048226022 Down 0.174799729 Nudt9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 K13988|1|0.0|635|mmu:74167|ADP-ribose pyrophosphatase [EC:3.6.1.13] GO:0043231//intracellular membrane-bounded organelle GO:0017110//nucleoside-diphosphatase activity GO:0009154//purine ribonucleotide catabolic process "gi|27753998|ref|NP_083070.2|/6.07487e-180/ADP-ribose pyrophosphatase, mitochondrial [Mus musculus]" 243043 2889 0.26 0.17 -0.612976877 Down 0.174799729 Kctd8 potassium channel tetramerisation domain containing 8 "K03849|1|5e-14|82.8|cmk:103177229|alpha-1,3-glucosyltransferase [EC:2.4.1.265];K20131|2|3e-08|63.5|cmy:102940364|Rab5 GDP/GTP exchange factor" GO:0043234//protein complex;GO:0097060//synaptic membrane - GO:0007186//G-protein coupled receptor signaling pathway;GO:0051259//protein oligomerization gi|65301477|ref|NP_780728.3|/0/BTB/POZ domain-containing protein KCTD8 [Mus musculus] 66525 1179 43.82 45.41 0.051420552 Up 0.174799729 Timm50 translocase of inner mitochondrial membrane 50 K17496|1|2e-176|620|mmu:66525|mitochondrial import inner membrane translocase subunit TIM50 GO:0031224//intrinsic component of membrane;GO:0016604//nuclear body;GO:0005743//mitochondrial inner membrane GO:0005488//binding;GO:0004721//phosphoprotein phosphatase activity GO:0006470//protein dephosphorylation;GO:0045184//establishment of protein localization;GO:0007005//mitochondrion organization gi|22094989|ref|NP_079892.1|/1.88162e-175/mitochondrial import inner membrane translocase subunit TIM50 precursor [Mus musculus] 76426 649 0.163333333 0.083333333 -0.970853654 Down 0.174790327 Fam209 family with sequence similarity 209 - - - - gi|198278455|ref|NP_083884.1|/7.49644e-97/uncharacterized protein LOC76426 precursor [Mus musculus] 21384 3585 0.086666667 0.166666667 0.943416472 Up 0.174790327 Tbx15 T-box 15 K10182|1|0.0|1108|mmu:21384|T-box protein 15 GO:0017053//transcriptional repressor complex GO:0044212//transcription regulatory region DNA binding;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0001104//RNA polymerase II transcription cofactor activity GO:0048704//embryonic skeletal system morphogenesis;GO:0006366//transcription from RNA polymerase II promoter gi|124286802|ref|NP_033349.2|/0/T-box transcription factor TBX15 [Mus musculus] 214105 2995 0.086666667 0.17 0.971985624 Up 0.174790327 Sox30 SRY (sex determining region Y)-box 30 K09271|1|0.0|1239|mmu:214105|transcription factor SOX15/30 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding GO:0006366//transcription from RNA polymerase II promoter gi|27734194|ref|NP_775560.1|/0/transcription factor SOX-30 [Mus musculus] 100503538 1826 0.086666667 0.17 0.971985624 Up 0.174790327 Gm15941 predicted gene 15941 K10486|1|7e-80|269|rno:171454|BTB/POZ domain-containing protein 14 - - - - 26886 1239 0.163333333 0.083333333 -0.970853654 Down 0.174790327 Cenph centromere protein H K11500|1|7e-110|399|mmu:26886|centromere protein H GO:0000776//kinetochore;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0051276//chromosome organization gi|11230784|ref|NP_068686.1|/5.64109e-109/centromere protein H [Mus musculus] 11886 2264 15.11333333 14.46 -0.063754338 Down 0.174780924 Asah1 N-acylsphingosine amidohydrolase 1 K12348|1|0.0|822|mmu:11886|acid ceramidase [EC:3.5.1.23] - - - - 100043597 10914 15.32666667 14.67333333 -0.062847321 Down 0.174780924 Srcap Snf2-related CREBBP activator protein K11661|1|0.0|2717|mmu:100043597|helicase SRCAP [EC:3.6.4.-] GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0008080//N-acetyltransferase activity GO:0016570//histone modification;GO:0006366//transcription from RNA polymerase II promoter gi|747019224|ref|NP_001291195.1|/0/helicase SRCAP [Mus musculus] 74094 2438.33 16.54 15.88666667 -0.058142784 Down 0.174780924 Tjap1 tight junction associated protein 1 K06105|1|0.0|828|mmu:74094|tight junction protein 4 (peripheral) GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|21311861|ref|NP_083027.1|/0/tight junction-associated protein 1 [Mus musculus] 217946 2626 0.04 0.11 1.459431619 Up 0.174752717 Cdca7l cell division cycle associated 7 like "K10408|1|1e-34|151|mmu:13411|dynein heavy chain, axonemal" GO:0031981//nuclear lumen - "GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation" "gi|148701531|gb|EDL33478.1|/0/cell division cycle associated 7 like, partial [Mus musculus]" 244954 2525 0.04 0.113333333 1.502500341 Up 0.174752717 Prss35 "protease, serine 35" K09627|1|2e-95|352|myd:102762969|serine protease 23 [EC:3.4.21.-] - - - - 114673 1382 0.11 0.04 -1.459431619 Down 0.174752717 4930433N12Rik RIKEN cDNA 4930433N12 gene - - - - - 243574 4521 0.11 0.04 -1.459431619 Down 0.174752717 Kbtbd8 kelch repeat and BTB (POZ) domain containing 8 K10475|1|0.0|1063|mmu:243574|kelch repeat and BTB domain-containing protein 8 - - - gi|156713458|ref|NP_001008785.2|/0/kelch repeat and BTB domain-containing protein 8 isoform a [Mus musculus] 71765 2084.67 49.69666667 51.28 0.045247174 Up 0.174733913 Klhdc3 kelch domain containing 3 K14966|1|2e-25|120|amj:102564528|host cell factor GO:0000785//chromatin GO:0005488//binding GO:0022403 gi|254910972|ref|NP_082186.2|/0/kelch domain-containing protein 3 [Mus musculus] 22275 1489 47.87 49.44666667 0.046751462 Up 0.174733913 Urod uroporphyrinogen decarboxylase K01599|1|0.0|676|mmu:22275|uroporphyrinogen decarboxylase [EC:4.1.1.37] - - - - 226977 2077 44.31666667 45.89666667 0.050540008 Up 0.174733913 Actr1b "ARP1 actin-related protein 1B, centractin beta" K16575|1|0.0|755|ngi:103738096|centractin GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0044444//cytoplasmic part GO:0032550 GO:0002478 gi|635078596|ref|XP_008006265.1|/0/PREDICTED: beta-centractin [Chlorocebus sabaeus] 19883 8708.03 2.97 3.21 0.112110366 Up 0.174658693 Rora RAR-related orphan receptor alpha K08532|1|0.0|976|mmu:19883|RAR-related orphan receptor alpha - - - - 232975 3609 0.27 0.18 -0.584962501 Down 0.174658693 Atp1a3 "ATPase, Na+/K+ transporting, alpha 3 polypeptide" K01539|1|0.0|1930|mmu:232975|sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9] GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane GO:0032550;GO:0008556//potassium-transporting ATPase activity;GO:0043169//cation binding GO:0042221//response to chemical;GO:0007626//locomotory behavior;GO:0007611//learning or memory;GO:0030001//metal ion transport;GO:0009152//purine ribonucleotide biosynthetic process;GO:0007632//visual behavior;GO:0007215//glutamate receptor signaling pathway "gi|148692349|gb|EDL24296.1|/0/ATPase, Na+/K+ transporting, alpha 3 polypeptide, isoform CRA_a, partial [Mus musculus]" 30956 3701 0.173333333 0.263333333 0.60334103 Up 0.174658693 Aass aminoadipate-semialdehyde synthase K14157|1|0.0|1784|mmu:30956|alpha-aminoadipic semialdehyde synthase [EC:1.5.1.8 1.5.1.9] GO:0043231//intracellular membrane-bounded organelle GO:0004753//saccharopine dehydrogenase activity GO:0019474 "gi|31980703|ref|NP_038958.2|/0/alpha-aminoadipic semialdehyde synthase, mitochondrial [Mus musculus]" 12326 12331 0.416666667 0.53 0.347098671 Up 0.174658693 Camk4 calcium/calmodulin-dependent protein kinase IV K05869|1|0.0|731|mmu:12326|calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0032550;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity "GO:0006351//transcription, DNA-templated;GO:0038127//ERBB signaling pathway;GO:0007613//memory;GO:0006611//protein export from nucleus;GO:0006796//phosphate-containing compound metabolic process;GO:0010863//positive regulation of phospholipase C activity;GO:0033077//T cell differentiation in thymus;GO:0007268//chemical synaptic transmission;GO:0006464//cellular protein modification process;GO:0002761//regulation of myeloid leukocyte differentiation;GO:0001773//myeloid dendritic cell activation;GO:0002371//dendritic cell cytokine production;GO:0006952//defense response" gi|569003057|ref|XP_006525606.1|/0/PREDICTED: calcium/calmodulin-dependent protein kinase type IV isoform X2 [Mus musculus] 75116 1217 0.4 0.51 0.350497247 Up 0.174658693 4930520O04Rik RIKEN cDNA 4930520O04 gene - - - - "gi|148677366|gb|EDL09313.1|/1.3817e-35/mCG145125, partial [Mus musculus]" 71838 1984 3.05 3.29 0.109278341 Up 0.174658693 Phf7 PHD finger protein 7 K19998|1|2e-68|262|apla:101795279|sec1 family domain-containing protein 1;K08592|2|1e-33|147|api:100574671|sentrin-specific protease 1 [EC:3.4.22.68];K09188|3|1e-06|57.8|gja:107123156|histone-lysine N-methyltransferase MLL3 [EC:2.1.1.43];K09187|4|2e-06|57.0|tru:101062458|histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43] GO:0016020//membrane;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding - gi|58865990|ref|NP_001012211.1|/0/PHD finger protein 7 [Rattus norvegicus] 237758 2079 0.263333333 0.173333333 -0.60334103 Down 0.174658693 Zfp454 zinc finger protein 454 K09228|1|0.0|1097|mmu:237758|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|31982552|ref|NP_766382.2|/0/zinc finger protein 454 [Mus musculus] 100504166 3850 1.043333333 1.196666667 0.197821187 Up 0.174630486 4933421O10Rik RIKEN cDNA 4933421O10 gene - - - - - 574428 2801 1.01 1.163333333 0.203909243 Up 0.174630486 Zmynd15 "zinc finger, MYND-type containing 15" - GO:0044424 GO:0046914//transition metal ion binding;GO:0019899//enzyme binding "GO:0048232//male gamete generation;GO:0007281//germ cell development;GO:0006351//transcription, DNA-templated" "gi|148680623|gb|EDL12570.1|/0/zinc finger, MYND-type containing 15, isoform CRA_c, partial [Mus musculus]" 100038570 816 0.68 0.556666667 -0.288721049 Down 0.174592877 Gm11744 predicted gene 11744 K19637|1|3e-23|111|mmu:100038570|progressive rod-cone degeneration protein GO:0044424;GO:0031224//intrinsic component of membrane - GO:0050953//sensory perception of light stimulus gi|74209506|dbj|BAE23299.1|/4.13269e-52/unnamed protein product [Mus musculus] 14744 2153 0.546666667 0.67 0.293499687 Up 0.174592877 Gpr65 G-protein coupled receptor 65 K08416|1|0.0|655|mmu:14744|G protein-coupled receptor 65 GO:0016021//integral component of membrane GO:0004888//transmembrane signaling receptor activity GO:0032233//positive regulation of actin filament bundle assembly;GO:0007166//cell surface receptor signaling pathway;GO:0012501//programmed cell death;GO:0009268//response to pH;GO:0006171//cAMP biosynthetic process;GO:0002376//immune system process;GO:0032502//developmental process gi|6680063|ref|NP_032178.1|/0/psychosine receptor [Mus musculus] 239839 4107 0.68 0.556666667 -0.288721049 Down 0.174592877 Ccdc14 coiled-coil domain containing 14 K16541|1|0.0|1620|mmu:239839|coiled-coil domain-containing protein 14 - - - gi|169646270|ref|NP_766412.2|/0/coiled-coil domain-containing protein 14 [Mus musculus] 414072 4197 0.39 0.286666667 -0.444099965 Down 0.174592877 BC031361 cDNA sequence BC031361 - - - - gi|74143770|dbj|BAE41215.1|/8.93049e-29/unnamed protein product [Mus musculus] 106052 3479 2.396666667 2.613333333 0.124861884 Up 0.174536462 Fbxo4 F-box protein 4 K10291|1|0.0|790|rno:310363|F-box protein 4 GO:0031461//cullin-RING ubiquitin ligase complex GO:0042802//identical protein binding;GO:0019787//ubiquitin-like protein transferase activity GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006259//DNA metabolic process;GO:0016567//protein ubiquitination gi|157818251|ref|NP_001101142.1|/0/F-box only protein 4 [Rattus norvegicus] 108995 1781 2.606666667 2.826666667 0.116895657 Up 0.174536462 Tbc1d10c "TBC1 domain family, member 10c" K19944|1|0.0|785|mmu:108995|TBC1 domain family member 10 GO:0044464 - - gi|126517465|ref|NP_848765.2|/0/carabin [Mus musculus] 71916 1768 2.8 2.583333333 -0.116193018 Down 0.174536462 Dus4l dihydrouridine synthase 4-like (S. cerevisiae) K05545|1|0.0|654|mmu:71916|tRNA-dihydrouridine synthase 4 [EC:1.3.1.90] - "GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0000166//nucleotide binding" GO:0006400//tRNA modification;GO:0044710 "gi|148704961|gb|EDL36908.1|/0/dihydrouridine synthase 4-like (S. cerevisiae), isoform CRA_a, partial [Mus musculus]" 51960 2380.35 2.476666667 2.693333333 0.120993082 Up 0.174536462 Kctd18 potassium channel tetramerisation domain containing 18 "K03849|1|8e-11|72.0|cmk:103177229|alpha-1,3-glucosyltransferase [EC:2.4.1.265];K11835|2|4e-10|69.7|sko:100377510|ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.4.19.12];K20131|3|2e-08|64.3|bacu:103015608|Rab5 GDP/GTP exchange factor" - GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity;GO:0015075//ion transmembrane transporter activity - gi|229577266|ref|NP_001153336.1|/0/BTB/POZ domain-containing protein KCTD18 isoform 1 [Mus musculus] 67199 1077 42.63666667 44.18666667 0.051516449 Up 0.17452706 Pfdn1 prefoldin 1 K09548|1|2e-47|192|rro:104681755|prefoldin subunit 1 GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0005515//protein binding GO:0046649//lymphocyte activation;GO:0051084//'de novo' posttranslational protein folding;GO:0007010//cytoskeleton organization;GO:0030900//forebrain development;GO:0022037//metencephalon development gi|514475096|ref|XP_003477193.2|/4.93891e-47/PREDICTED: prefoldin subunit 1 [Cavia porcellus] 78757 9328 0.79 0.663333333 -0.252118628 Down 0.174461243 Rictor "RPTOR independent companion of MTOR, complex 2" K08267|1|0.0|3087|mmu:78757|rapamycin-insensitive companion of mTOR - - - gi|168480120|ref|NP_084444.3|/0/rapamycin-insensitive companion of mTOR [Mus musculus] 67299 7049 0.673333333 0.8 0.248679113 Up 0.174461243 Dock7 dedicator of cytokinesis 7 K13708|1|3e-14|85.1|crg:105338650|dedicator of cytokinesis protein 1;K05727|2|2e-12|79.0|oas:101114650|dedicator of cytokinesis protein 3 - - - gi|594591539|ref|NP_001277565.1|/0/dedicator of cytokinesis protein 7 isoform 1 [Mus musculus] 381482 2424 0.106666667 0.04 -1.415037499 Down 0.174433036 Gm1653 predicted gene 1653 - - - - - 327860 1319 0.116666667 0.043333333 -1.428843299 Down 0.174433036 Gm11961 predicted gene 11961 - - - - "gi|148708535|gb|EDL40482.1|/4.31386e-78/hypothetical protein A930010I02, partial [Mus musculus]" 69338 1389 0.106666667 0.04 -1.415037499 Down 0.174433036 1700003D09Rik RIKEN cDNA 1700003D09 gene K15494|1|3e-08|62.4|cge:100758739|protein phosphatase 1 regulatory subunit 1B GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0005737//cytoplasm GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding GO:0045924//regulation of female receptivity;GO:0044092//negative regulation of molecular function;GO:0007632//visual behavior;GO:0007165//signal transduction;GO:0010467//gene expression "gi|148684185|gb|EDL16132.1|/8.24537e-51/mCG146187, partial [Mus musculus]" 72614 1268 0.116666667 0.043333333 -1.428843299 Down 0.174433036 Pih1d2 PIH1 domain containing 2 "K19751|1|1e-07|60.5|mze:101472379|dynein assembly factor 2, axonemal" - - - gi|568960111|ref|XP_006510690.1|/1.04264e-166/PREDICTED: PIH1 domain-containing protein 2 isoform X1 [Mus musculus] 214158 1480 0.04 0.106666667 1.415037499 Up 0.174433036 Trim38 tripartite motif-containing 38 K12014|1|0.0|980|mmu:214158|tripartite motif-containing protein 38 [EC:2.3.2.27] - GO:0043169//cation binding;GO:0060089 GO:0019079//viral genome replication;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0002698;GO:0032479//regulation of type I interferon production;GO:0000209//protein polyubiquitination;GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|71480134|ref|NP_001025106.1|/0/E3 ubiquitin-protein ligase TRIM38 [Mus musculus] 320604 2171 0.106666667 0.04 -1.415037499 Down 0.174433036 Ccdc169 coiled-coil domain containing 169 - - - - gi|222418583|ref|NP_796177.2|/2.47449e-88/coiled-coil domain-containing protein 169 isoform a [Mus musculus] 233913 2605 3.523333333 3.783333333 0.102716921 Up 0.174310805 BC017158 cDNA sequence BC017158 "K10696|1|6e-64|248|asn:102376595|E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27];K14382|2|3e-26|93.2|umr:103657894|solute carrier family 5 (sodium/glucose cotransporter), member 2" GO:0031224//intrinsic component of membrane - - gi|225579041|ref|NP_663565.2|/0/RUS1 family protein C16orf58 homolog [Mus musculus] 74196 2839 3.603333333 3.866666667 0.101758282 Up 0.174310805 Ttc27 tetratricopeptide repeat domain 27 K16531|1|2e-06|57.8|clv:102093228|Bardet-Biedl syndrome 4 protein - - - "gi|148706495|gb|EDL38442.1|/0/tetratricopeptide repeat domain 27, isoform CRA_c, partial [Mus musculus]" 23939 3072.56 3.866666667 3.603333333 -0.101758282 Down 0.174310805 Mapk7 mitogen-activated protein kinase 7 K04464|1|0.0|1037|mmu:23939|mitogen-activated protein kinase 7 [EC:2.7.11.24] GO:0016604//nuclear body;GO:0044444//cytoplasmic part;GO:0016604//nuclear body;GO:0044444//cytoplasmic part;GO:0016604//nuclear body;GO:0044444//cytoplasmic part;GO:0016604//nuclear body;GO:0044444//cytoplasmic part;GO:0016604//nuclear body;GO:0044444//cytoplasmic part;GO:0016604//nuclear body;GO:0044444//cytoplasmic part GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0019901//protein kinase binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0019901//protein kinase binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0019901//protein kinase binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0019901//protein kinase binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0019901//protein kinase binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0019901//protein kinase binding GO:0001525//angiogenesis;GO:0071363//cellular response to growth factor stimulus;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0034614//cellular response to reactive oxygen species;GO:0006915//apoptotic process;GO:0010604;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0034097//response to cytokine;GO:0034616//response to laminar fluid shear stress;GO:0022408//negative regulation of cell-cell adhesion;GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade;GO:0001525//angiogenesis;GO:0071363//cellular response to growth factor stimulus;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0034614//cellular response to reactive oxygen species;GO:0006915//apoptotic process;GO:0010604;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0034097//response to cytokine;GO:0034616//response to laminar fluid shear stress;GO:0022408//negative regulation of cell-cell adhesion;GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade;GO:0001525//angiogenesis;GO:0071363//cellular response to growth factor stimulus;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0034614//cellular response to reactive oxygen species;GO:0006915//apoptotic process;GO:0010604;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0034097//response to cytokine;GO:0034616//response to laminar fluid shear stress;GO:0022408//negative regulation of cell-cell adhesion;GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade;GO:0001525//angiogenesis;GO:0071363//cellular response to growth factor stimulus;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0034614//cellular response to reactive oxygen species;GO:0006915//apoptotic process;GO:0010604;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0034097//response to cytokine;GO:0034616//response to laminar fluid shear stress;GO:0022408//negative regulation of cell-cell adhesion;GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade;GO:0001525//angiogenesis;GO:0071363//cellular response to growth factor stimulus;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0034614//cellular response to reactive oxygen species;GO:0006915//apoptotic process;GO:0010604;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0034097//response to cytokine;GO:0034616//response to laminar fluid shear stress;GO:0022408//negative regulation of cell-cell adhesion;GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade;GO:0001525//angiogenesis;GO:0071363//cellular response to growth factor stimulus;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0034614//cellular response to reactive oxygen species;GO:0006915//apoptotic process;GO:0010604;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0034097//response to cytokine;GO:0034616//response to laminar fluid shear stress;GO:0022408//negative regulation of cell-cell adhesion;GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade gi|6754634|ref|NP_035971.1|/0/mitogen-activated protein kinase 7 isoform a [Mus musculus] 218503 5141 3.716666667 3.976666667 0.097550333 Up 0.174310805 Fcho2 FCH domain only 2 K20042|1|0.0|1443|mmu:218503|F-BAR domain only protein - - - - 64293 3458 0.096666667 0.18 0.896906507 Up 0.174197977 Stk32b serine/threonine kinase 32B K08793|1|0.0|825|mmu:64293|serine/threonine kinase 32 [EC:2.7.11.1] - GO:0043169//cation binding;GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|33468971|ref|NP_071861.1|/0/serine/threonine-protein kinase 32B [Mus musculus] 71020 1160 0.173333333 0.093333333 -0.893084796 Down 0.174197977 Spats1 "spermatogenesis associated, serine-rich 1" - - - - gi|169808394|ref|NP_081925.2|/2.67603e-142/spermatogenesis-associated serine-rich protein 1 [Mus musculus] 626904 1565 0.093333333 0.173333333 0.893084796 Up 0.174197977 Gm20756 "predicted gene, 20756" - - - - - 329513 3433 0.173333333 0.093333333 -0.893084796 Down 0.174197977 A730036I17Rik RIKEN cDNA A730036I17 gene - - - - - 20431 2130 1.22 1.383333333 0.181267688 Up 0.174188574 Pmel premelanosome protein K17304|1|0.0|1059|mmu:20431|melanocyte protein PMEL - - - - 20913 6035 1.216666667 1.38 0.181734304 Up 0.174188574 Stxbp4 syntaxin binding protein 4 K15302|1|0.0|1040|mmu:20913|syntaxin-binding protein 4 GO:0044424 GO:0005488//binding GO:0008645//hexose transport;GO:0006886//intracellular protein transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|6755692|ref|NP_035635.1|/0/syntaxin-binding protein 4 [Mus musculus] 68306 2416 0.113333333 0.043333333 -1.387023123 Down 0.17413216 4930565N06Rik RIKEN cDNA 4930565N06 gene - - - - gi|148665532|gb|EDK97948.1|/1.1387e-06/mCG128247 [Mus musculus] 70487 2031 0.12 0.046666667 -1.362570079 Down 0.17413216 5730403I07Rik RIKEN cDNA 5730403I07 gene - - - - gi|148694401|gb|EDL26348.1|/4.53662e-38/mCG129936 [Mus musculus] 233799 6542 0.046666667 0.116666667 1.321928095 Up 0.17413216 Acsm2 acyl-CoA synthetase medium-chain family member 2 K01896|1|0.0|1177|mmu:233799|medium-chain acyl-CoA synthetase [EC:6.2.1.2] - - - - 16622 862 0.01 0.063333333 2.662965013 Up 0.17409455 Klk1b5 kallikrein 1-related peptidase b5 "K01325|1|5e-158|558|mmu:16622|tissue kallikrein [EC:3.4.21.35];K05451|5|5e-126|452|mmu:18048|nerve growth factor, alpha" GO:0044421 GO:0043169//cation binding;GO:0004871//signal transducer activity;GO:0004175//endopeptidase activity;GO:0005102//receptor binding GO:0035556//intracellular signal transduction;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0019538//protein metabolic process gi|7949064|ref|NP_032482.1|/4.02824e-157/kallikrein 1-related peptidase b5 preproprotein [Mus musculus] 17140 948 0.06 0.01 -2.584962501 Down 0.17409455 Magea4 "melanoma antigen, family A, 4" K12464|1|6e-35|150|cge:100768434|melanoma-associated antigen D1 - - - "gi|255759895|ref|NP_064676.2|/4.31579e-166/melanoma antigen family A, 4 [Mus musculus] " 22127 842 0.01 0.063333333 2.662965013 Up 0.17409455 Tsx testis specific X-linked gene - GO:0043231//intracellular membrane-bounded organelle - GO:0019953//sexual reproduction;GO:0008406//gonad development gi|6678451|ref|NP_033466.1|/1.44516e-71/testis-specific protein TSX [Mus musculus] 19127 1000 0.01 0.063333333 2.662965013 Up 0.17409455 Prop1 paired like homeodomain factor 1 K09327|1|2e-92|341|mmu:19127|homeobox protein prophet of Pit-1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005515//protein binding;GO:0003677//DNA binding GO:0009653//anatomical structure morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0001944//vasculature development;GO:0006915//apoptotic process;GO:0048870//cell motility;GO:0003002//regionalization;GO:0021984//adenohypophysis development;GO:0021854//hypothalamus development gi|6679481|ref|NP_032962.1|/1.30631e-91/homeobox protein prophet of Pit-1 [Mus musculus] 243958 2484 0.01 0.063333333 2.662965013 Up 0.17409455 Siglecg sialic acid binding Ig-like lectin G K06749|1|0.0|1345|mmu:243958|sialic acid binding Ig-like lectin 10 GO:0031224//intrinsic component of membrane - - gi|151301230|ref|NP_766488.2|/0/sialic acid-binding Ig-like lectin 10 precursor [Mus musculus] 57757 2519 0.01 0.063333333 2.662965013 Up 0.17409455 Pglyrp2 peptidoglycan recognition protein 2 K01446|1|5e-160|567|mmu:57757|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] - "GO:0008329//signaling pattern recognition receptor activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0046914//transition metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0008329//signaling pattern recognition receptor activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0046914//transition metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0008329//signaling pattern recognition receptor activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0046914//transition metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0008329//signaling pattern recognition receptor activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0046914//transition metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0008329//signaling pattern recognition receptor activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0046914//transition metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0008329//signaling pattern recognition receptor activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0046914//transition metal ion binding;GO:0005539//glycosaminoglycan binding" GO:0042742//defense response to bacterium;GO:0000270//peptidoglycan metabolic process;GO:0001818//negative regulation of cytokine production;GO:0044116;GO:0002325;GO:0009581;GO:0042742//defense response to bacterium;GO:0000270//peptidoglycan metabolic process;GO:0001818//negative regulation of cytokine production;GO:0044116;GO:0002325;GO:0009581;GO:0042742//defense response to bacterium;GO:0000270//peptidoglycan metabolic process;GO:0001818//negative regulation of cytokine production;GO:0044116;GO:0002325;GO:0009581;GO:0042742//defense response to bacterium;GO:0000270//peptidoglycan metabolic process;GO:0001818//negative regulation of cytokine production;GO:0044116;GO:0002325;GO:0009581;GO:0042742//defense response to bacterium;GO:0000270//peptidoglycan metabolic process;GO:0001818//negative regulation of cytokine production;GO:0044116;GO:0002325;GO:0009581;GO:0042742//defense response to bacterium;GO:0000270//peptidoglycan metabolic process;GO:0001818//negative regulation of cytokine production;GO:0044116;GO:0002325;GO:0009581 gi|6651241|gb|AAF22234.1|AF149838_1/0/TAGL-beta [Mus musculus] 11828 1763 0.063333333 0.01 -2.662965013 Down 0.17409455 Aqp3 aquaporin 3 K09876|1|9e-170|599|mmu:11828|aquaporin-3 GO:0030054//cell junction;GO:0016021//integral component of membrane;GO:0044459;GO:0044424 GO:0005372//water transmembrane transporter activity;GO:0015168//glycerol transmembrane transporter activity GO:0033993//response to lipid;GO:0044763;GO:0019755;GO:0003097//renal water transport;GO:0008643//carbohydrate transport gi|121949813|ref|NP_057898.2|/7.86055e-169/aquaporin-3 [Mus musculus] 214106 1783 0.06 0.01 -2.584962501 Down 0.17409455 4933430I17Rik RIKEN cDNA 4933430I17 gene K07524|1|2e-75|286|bacu:102998799|regulator of G-protein signalling 3 - - - gi|29243978|ref|NP_808275.1|/0/uncharacterized protein C9orf43 homolog [Mus musculus] 382077 2555 0.06 0.01 -2.584962501 Down 0.17409455 Ccdc33 coiled-coil domain containing 33 "K15032|1|2e-49|200|xtr:100145192|mTERF domain-containing protein, mitochondrial" GO:0042579//microbody - GO:0048232//male gamete generation gi|261399871|ref|NP_001159754.1|/0/coiled-coil domain-containing protein 33 isoform 1 [Mus musculus] 233038 1531 0.01 0.063333333 2.662965013 Up 0.17409455 Nccrp1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) K10102|1|3e-23|112|xtr:779735|F-box protein 27;K01875|3|8e-21|104|cmy:102932242|seryl-tRNA synthetase [EC:6.1.1.11];K10099|4|6e-19|98.2|gja:107108923|F-box protein 2 GO:0044424 - GO:0008283//cell proliferation gi|124487435|ref|NP_001074584.1|/3.6992e-156/F-box only protein 50 [Mus musculus] 240121 1748 0.063333333 0.01 -2.662965013 Down 0.17409455 Fsd1 fibronectin type 3 and SPRY domain-containing protein K08285|1|7e-51|204|lcm:102351326|midline 1 [EC:2.3.2.27] GO:0032155;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton - GO:0000087//mitotic M phase gi|34147224|ref|NP_899001.1|/0/fibronectin type III and SPRY domain-containing protein 1 [Mus musculus] 18548 2516 0.063333333 0.01 -2.662965013 Down 0.17409455 Pcsk1 proprotein convertase subtilisin/kexin type 1 K01359|1|0.0|1480|mmu:18548|proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93] - - - gi|7305371|ref|NP_038656.1|/0/neuroendocrine convertase 1 precursor [Mus musculus] 13101 1681 0.01 0.06 2.584962501 Up 0.17409455 Cyp2d10 "cytochrome P450, family 2, subfamily d, polypeptide 10" "K07414|1|0.0|1001|mmu:13101|cytochrome P450, family 2, subfamily D [EC:1.14.14.1]" GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0010033//response to organic substance;GO:0044710 gi|31981816|ref|NP_034135.2|/0/cytochrome P450 2D10 [Mus musculus] 16630 870 0.063333333 0.01 -2.662965013 Down 0.17409455 Klra12 "killer cell lectin-like receptor subfamily A, member 12" K17515|1|3e-16|88.2|cmy:102931345|C-type lectin domain family 9 member A;K06541|3|2e-14|81.6|bom:106700967|killer cell lectin-like receptor subfamily C GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0022610 "gi|21327665|ref|NP_034776.1|/2.95259e-147/killer cell lectin-like receptor subfamily A, member 12 [Mus musculus]" 53880 4841 0.063333333 0.01 -2.662965013 Down 0.17409455 Naip7 "NLR family, apoptosis inhibitory protein 7" K12807|1|0.0|2800|mmu:53880|baculoviral IAP repeat-containing protein 1 GO:0043234//protein complex;GO:0044464 GO:0043169//cation binding;GO:0032550 GO:0042742//defense response to bacterium;GO:0009581;GO:0012501//programmed cell death gi|58866050|ref|NP_067520.1|/0/baculoviral IAP repeat-containing protein 1g [Mus musculus] 381196 2262 0.01 0.06 2.584962501 Up 0.17409455 Gm960 predicted gene 960 K08658|1|5e-30|135|cmy:102940344|prenyl protein peptidase [EC:3.4.22.-];K14970|2|6e-16|89.0|lcm:102348464|menin - - - gi|353523843|ref|NP_001028619.2|/0/putative uncharacterized protein C11orf80 homolog [Mus musculus] 15417 2711 0.01 0.06 2.584962501 Up 0.17409455 Hoxb9 homeobox B9 K09294|1|5e-137|491|rno:287647|homeobox protein HoxA/B/C/D9 GO:0031981//nuclear lumen GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0003002//regionalization;GO:0016055//Wnt signaling pathway;GO:0006935//chemotaxis;GO:0001501//skeletal system development;GO:0048732//gland development;GO:0006366//transcription from RNA polymerase II promoter gi|113680760|ref|NP_032296.2|/3.90593e-136/homeobox protein Hox-B9 [Mus musculus] 258918 942 0.06 0.01 -2.584962501 Down 0.17409455 Olfr1346 olfactory receptor 1346 K04257|1|6e-179|628|mmu:258918|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007154//cell communication gi|22129063|ref|NP_667127.1|/4.85887e-178/olfactory receptor 1346 [Mus musculus] 14620 1601 0.01 0.06 2.584962501 Up 0.17409455 Gjb3 "gap junction protein, beta 3" "K07622|1|1e-135|485|mmu:14620|gap junction protein, beta 3" GO:0005921//gap junction;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0005921//gap junction;GO:0031224//intrinsic component of membrane;GO:0044424 GO:0005488//binding;GO:0022829//wide pore channel activity;GO:0005488//binding;GO:0022829//wide pore channel activity GO:0043009//chordate embryonic development;GO:0044763;GO:0008544//epidermis development;GO:0050954//sensory perception of mechanical stimulus;GO:0043009//chordate embryonic development;GO:0044763;GO:0008544//epidermis development;GO:0050954//sensory perception of mechanical stimulus gi|6680013|ref|NP_032152.1|/1.11677e-134/gap junction beta-3 protein [Mus musculus] 18307 936 0.063333333 0.01 -2.662965013 Down 0.17409455 Olfr10 olfactory receptor 10 K04257|1|7e-169|595|mmu:18307|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|45592946|ref|NP_996558.1|/5.88453e-168/olfactory receptor 10 [Mus musculus] 12427 1581 0.01 0.063333333 2.662965013 Up 0.17409455 Ccna1 cyclin A1 K06627|1|0.0|849|mmu:12427|cyclin A GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle GO:0019900//kinase binding GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0000087//mitotic M phase "gi|148703343|gb|EDL35290.1|/0/cyclin A1, isoform CRA_b, partial [Mus musculus]" 78629 878 0.01 0.063333333 2.662965013 Up 0.17409455 1700072I22Rik RIKEN cDNA 1700072I22 gene - - - - - 74448 1742 0.063333333 0.01 -2.662965013 Down 0.17409455 Arl13a ADP-ribosylation factor-like 13A K07961|1|0.0|753|mmu:74448|ADP-ribosylation factor-like protein 13 GO:0044464 GO:0032550 GO:0035556//intracellular signal transduction gi|241982691|ref|NP_083223.1|/0/ADP-ribosylation factor-like protein 13A [Mus musculus] 259096 945 0.063333333 0.01 -2.662965013 Down 0.17409455 Olfr561 olfactory receptor 561 K04257|1|1e-159|564|mmu:259096|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|22128785|ref|NP_667303.1|/8.6664e-159/olfactory receptor 561 [Mus musculus] 72168 2302 0.01 0.063333333 2.662965013 Up 0.17409455 Aifm3 "apoptosis-inducing factor, mitochondrion-associated 3" K04727|1|8e-20|101|nvi:100119729|programmed cell death 8 (apoptosis-inducing factor) [EC:1.-.-.-] GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0000166//nucleotide binding;GO:0003824//catalytic activity GO:0012502//induction of programmed cell death;GO:0044710;GO:0006091//generation of precursor metabolites and energy;GO:0051881//regulation of mitochondrial membrane potential;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051234//establishment of localization;GO:0012502//induction of programmed cell death;GO:0044710;GO:0006091//generation of precursor metabolites and energy;GO:0051881//regulation of mitochondrial membrane potential;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051234//establishment of localization "gi|148665046|gb|EDK97462.1|/0/RIKEN cDNA 2810401C16, isoform CRA_c, partial [Mus musculus]" 14064 2464 0.063333333 0.01 -2.662965013 Down 0.17409455 F2rl2 coagulation factor II (thrombin) receptor-like 2 K04235|1|0.0|752|mmu:14064|coagulation factor II (thrombin) receptor-like 2 GO:0044459;GO:0031224//intrinsic component of membrane GO:0008528//G-protein coupled peptide receptor activity GO:0007599//hemostasis;GO:0006950//response to stress gi|153791954|ref|NP_034300.3|/0/proteinase-activated receptor 3 precursor [Mus musculus] 226957 914 0.01 0.06 2.584962501 Up 0.17409455 Gm4850 THO complex 4 pseudogene K12881|1|1e-82|308|mmu:100043292|THO complex subunit 4 - - - - 226049 2337 0.01 0.06 2.584962501 Up 0.17409455 Dmrt2 doublesex and mab-3 related transcription factor 2 K19489|1|0.0|942|mmu:226049|doublesex- and mab-3-related transcription factor 2 - GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity GO:0012502//induction of programmed cell death;GO:0008406//gonad development gi|74150053|dbj|BAE24347.1|/0/unnamed protein product [Mus musculus] 79459 1692 0.063333333 0.01 -2.662965013 Down 0.17409455 Aldoart2 "aldolase 1 A, retrogene 2" "K01623|1|0.0|656|cjc:100394290|fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0005856//cytoskeleton GO:0005515//protein binding;GO:0016832//aldehyde-lyase activity;GO:0048029//monosaccharide binding GO:0022604//regulation of cell morphogenesis;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006007//glucose catabolic process;GO:0006936//muscle contraction;GO:0019725//cellular homeostasis "gi|148704778|gb|EDL36725.1|/0/mCG22349, partial [Mus musculus]" 654462 869 0.01 0.063333333 2.662965013 Up 0.17409455 Kncn kinocilin - GO:0031513//nonmotile primary cilium;GO:0005815//microtubule organizing center;GO:0044459;GO:0030864//cortical actin cytoskeleton;GO:0044297//cell body;GO:0031513//nonmotile primary cilium;GO:0005815//microtubule organizing center;GO:0044459;GO:0030864//cortical actin cytoskeleton;GO:0044297//cell body - - gi|1001624549|ref|NP_001307474.1|/2.52704e-48/kinocilin isoform 1 [Mus musculus] 245347 939 0.063333333 0.01 -2.662965013 Down 0.17409455 Gm4984 predicted pseudogene 4984 - - - - gi|168229152|ref|NP_001094954.1|/3.35502e-54/mitochondrial pyruvate carrier 1-like protein [Mus musculus] 12623 2289 0.01 0.06 2.584962501 Up 0.17409455 Ces1g carboxylesterase 1G K01044|1|0.0|912|ngi:103731689|carboxylesterase 1 [EC:3.1.1.1] GO:0043231//intracellular membrane-bounded organelle GO:0052689//carboxylic ester hydrolase activity - gi|148679152|gb|EDL11099.1|/0/mCG9581 [Mus musculus] 258405 930 0.01 0.06 2.584962501 Up 0.17409455 Olfr1420 olfactory receptor 1420 K04257|1|1e-158|561|mmu:258405|olfactory receptor GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|33238900|ref|NP_666522.1|/9.30648e-158/olfactory receptor 1420 [Mus musculus] 258471 951 0.01 0.06 2.584962501 Up 0.17409455 Olfr891 olfactory receptor 891 K04257|1|4e-163|576|mmu:258471|olfactory receptor - - - gi|121582635|ref|NP_666689.2|/2.91141e-162/olfactory receptor 891 [Mus musculus] 554292 1449 0.01 0.063333333 2.662965013 Up 0.17409455 Methig1 methyltransferase hypoxia inducible domain containing 1 - GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle GO:0016741 GO:0008152//metabolic process "gi|148672144|gb|EDL04091.1|/5.68807e-151/mCG8150, isoform CRA_a, partial [Mus musculus]" 75178 1703 0.01 0.06 2.584962501 Up 0.17409455 Meiob meiosis specific with OB domains - - - - gi|254675140|ref|NP_083473.1|/0/meiosis-specific with OB domain-containing protein [Mus musculus] 232408 1554 0.01 0.063333333 2.662965013 Up 0.17409455 Klrb1f killer cell lectin-like receptor subfamily B member 1F K06543|1|8e-58|227|mmu:232408|killer cell lectin-like receptor subfamily B GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464 GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - gi|568941678|ref|XP_006506099.1|/2.12168e-72/PREDICTED: killer cell lectin-like receptor subfamily B member 1F isoform X3 [Mus musculus] 70026 935 0.06 0.01 -2.584962501 Down 0.17409455 Tspo2 translocator protein 2 K05770|1|3e-19|98.2|mdo:100030011|benzodiazapine receptor GO:0016020//membrane GO:0032934//sterol binding - "gi|148691677|gb|EDL23624.1|/2.03883e-120/benzodiazapine receptor, peripheral-like 1, partial [Mus musculus]" 69301 886 0.01 0.063333333 2.662965013 Up 0.17409455 Tescl tescalcin-like K17612|1|2e-129|463|mmu:69301|calcineurin B homologous protein 3 - - - gi|255304943|ref|NP_001157282.1|/1.84266e-128/tescalcin-like [Mus musculus] 19368 1546 0.01 0.06 2.584962501 Up 0.17409455 Raet1a "retinoic acid early transcript 1, alpha" K07987|1|3e-123|444|mmu:19368|retinoic acid early transcript 1 GO:0046658//anchored component of plasma membrane;GO:0009986//cell surface GO:0005102//receptor binding GO:0032496//response to lipopolysaccharide;GO:0030101//natural killer cell activation;GO:0006809//nitric oxide biosynthetic process;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0001819//positive regulation of cytokine production;GO:0002696//positive regulation of leukocyte activation;GO:0043330//response to exogenous dsRNA gi|6679617|ref|NP_033042.1|/2.72008e-122/retinoic acid early-inducible protein 1-alpha precursor [Mus musculus] 16191 1534 0.01 0.06 2.584962501 Up 0.17409455 Il5 interleukin 5 K05428|1|4e-70|268|mmu:16191|interleukin 5 GO:0044421 GO:0005126//cytokine receptor binding "GO:0001934//positive regulation of protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0007166//cell surface receptor signaling pathway;GO:0030222//eosinophil differentiation;GO:0007259//JAK-STAT cascade;GO:0048305//immunoglobulin secretion;GO:0030888//regulation of B cell proliferation;GO:0031334//positive regulation of protein complex assembly;GO:0044093;GO:0006952//defense response" gi|755537480|ref|XP_011247067.1|/7.67066e-77/PREDICTED: interleukin-5 isoform X1 [Mus musculus] 77772 2342 0.01 0.06 2.584962501 Up 0.17409455 Dcst1 DC-STAMP domain containing 1 K06836|1|0.0|912|fca:101095312|disintegrin and metalloproteinase domain-containing protein 15 [EC:3.4.24.-] GO:0031224//intrinsic component of membrane GO:0043169//cation binding - gi|116812883|ref|NP_084250.1|/0/DC-STAMP domain-containing protein 1 [Mus musculus] 70972 774 0.01 0.063333333 2.662965013 Up 0.17409455 4931420L22Rik RIKEN cDNA 4931420L22 gene - - - - - 16770 733 0.01 0.063333333 2.662965013 Up 0.17409455 Lalba "lactalbumin, alpha" K00704|1|4e-73|276|mmu:16770|alpha-lactalbumin [EC:2.4.1.22] - - - - 14941 937 0.06 0.01 -2.584962501 Down 0.17409455 Gzmd granzyme D K09616|1|2e-70|268|ngi:103739404|granzyme H (cathepsin G-like 2) [EC:3.4.21.-];K01353|3|1e-69|265|cge:100754015|granzyme B [EC:3.4.21.79] - GO:0004175//endopeptidase activity GO:0008219//cell death;GO:0019538//protein metabolic process "gi|148704264|gb|EDL36211.1|/2.93044e-135/mCG130831, isoform CRA_a, partial [Mus musculus]" 74693 1526 0.01 0.063333333 2.662965013 Up 0.17409455 4930509J09Rik RIKEN cDNA 4930509J09 gene - - - - "gi|148683537|gb|EDL15484.1|/1.3585e-33/mCG1032438, partial [Mus musculus]" 65971 932 0.01 0.06 2.584962501 Up 0.17409455 Tbata "thymus, brain and testes associated" - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - GO:0003006//developmental process involved in reproduction;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0003006//developmental process involved in reproduction;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0003006//developmental process involved in reproduction;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0003006//developmental process involved in reproduction;GO:0048232//male gamete generation;GO:0048869//cellular developmental process "gi|148700206|gb|EDL32153.1|/3.27309e-109/RIKEN cDNA 1700021K02, isoform CRA_c, partial [Mus musculus]" 93841 1162 0.01 0.06 2.584962501 Up 0.17409455 Uchl4 ubiquitin carboxyl-terminal esterase L4 K05609|1|3e-132|473|mmu:93841|ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle "GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0016790//thiolester hydrolase activity;GO:0032182//ubiquitin-like protein binding" GO:0043010//camera-type eye development;GO:0008344//adult locomotory behavior;GO:0019941//modification-dependent protein catabolic process;GO:0032868//response to insulin;GO:0045444//fat cell differentiation;GO:0007631//feeding behavior gi|15809026|ref|NP_291085.1|/2.77569e-131/ubiquitin carboxyl-terminal hydrolase isozyme L4 [Mus musculus] 414079 956 0.06 0.01 -2.584962501 Down 0.17409455 4930405O22Rik RIKEN cDNA 4930405O22 gene - - - - - 11846 1489 0.01 0.063333333 2.662965013 Up 0.17409455 Arg1 "arginase, liver" K01476|1|0.0|652|mmu:11846|arginase [EC:3.5.3.1] - - - - 76942 935 0.06 0.01 -2.584962501 Down 0.17409455 Lypd5 Ly6/Plaur domain containing 5 "K09435|1|2e-10|68.6|asn:102371936|transcriptional regulator ERG;K03985|2|8e-08|60.1|acs:103279307|plasminogen activator, urokinase receptor;K06552|3|8e-08|60.1|bom:102274130|CD177 antigen" GO:0031224//intrinsic component of membrane - - gi|118150404|ref|NP_084082.1|/4.66769e-141/ly6/PLAUR domain-containing protein 5 precursor [Mus musculus] 72973 1681 0.063333333 0.01 -2.662965013 Down 0.17409455 Fbxo47 F-box protein 47 K10321|1|0.0|914|mmu:72973|F-box protein 47 - - - gi|124487431|ref|NP_001074904.1|/0/F-box only protein 47 [Mus musculus] 77806 958 0.01 0.06 2.584962501 Up 0.17409455 A930019D19Rik RIKEN cDNA A930019D19 gene - - - - - 66269 863 0.063333333 0.01 -2.662965013 Down 0.17409455 Tmed6 transmembrane emp24 protein transport domain containing 6 K20351|1|7e-126|452|mmu:66269|p24 family protein gamma-5 GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0051234//establishment of localization gi|13384864|ref|NP_079734.1|/5.31008e-125/transmembrane emp24 domain-containing protein 6 precursor [Mus musculus] 26950 1951 0.06 0.01 -2.584962501 Down 0.17409455 Vsnl1 visinin-like 1 K19936|1|7e-107|390|lve:103075203|visinin-like protein 1 - GO:0046872//metal ion binding GO:0019932//second-messenger-mediated signaling;GO:0007399//nervous system development gi|880932026|ref|XP_012975277.1|/9.73725e-107/PREDICTED: visinin-like protein 1 isoform X1 [Mesocricetus auratus] 76925 744 0.01 0.063333333 2.662965013 Up 0.17409455 1700015E13Rik RIKEN cDNA 1700015E13 gene - - - - "gi|148707210|gb|EDL39157.1|/1.92026e-119/mCG10643, partial [Mus musculus]" 76676 1644 0.063333333 0.01 -2.662965013 Down 0.17409455 5330411J11Rik RIKEN cDNA 5330411J11 gene - - - - - 77171 902 0.01 0.063333333 2.662965013 Up 0.17409455 8030455M16Rik RIKEN cDNA 8030455M16 gene - - - - - 100885838 80 0.06 0.01 -2.584962501 Down 0.17409455 Mir5625 microRNA 5625 - - - - - 75100 936 0.01 0.06 2.584962501 Up 0.17409455 4930525D18Rik RIKEN cDNA 4930525D18 gene - - - - - 11905 2171 0.01 0.063333333 2.662965013 Up 0.17409455 Serpinc1 "serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1" K03911|1|0.0|895|mmu:11905|antithrombin III - - - gi|18252782|ref|NP_543120.1|/0/antithrombin-III precursor [Mus musculus] 70934 1704 0.06 0.01 -2.584962501 Down 0.17409455 4931403G20Rik RIKEN cDNA 4931403G20 gene - - - - gi|148704649|gb|EDL36596.1|/2.37888e-30/mCG1041620 [Mus musculus] 100038545 1523 0.01 0.06 2.584962501 Up 0.17409455 Gm10745 predicted gene 10745 - - - - - 71000 891 0.01 0.06 2.584962501 Up 0.17409455 4931440J10Rik RIKEN cDNA 4931440J10 gene - - - - - 435528 873 0.063333333 0.01 -2.662965013 Down 0.17409455 Glyatl3 glycine-N-acyltransferase-like 3 K00628|1|8e-45|182|oaa:100081664|glycine N-acyltransferase [EC:2.3.1.13] GO:0043231//intracellular membrane-bounded organelle GO:0016410//N-acyltransferase activity - gi|222831636|ref|NP_001138532.1|/4.87658e-166/glycine N-acyltransferase-like protein 3 [Mus musculus] 100384890 884 0.01 0.063333333 2.662965013 Up 0.17409455 D230030E09Rik Riken cDNA D230030E09 gene - - - - "gi|148701534|gb|EDL33481.1|/4.30947e-53/mCG145515, partial [Mus musculus]" 101055671 2805 0.01 0.06 2.584962501 Up 0.17409455 LOC101055671 "lipase, member O2" K14452|1|2e-154|549|cge:100757425|gastric triacylglycerol lipase [EC:3.1.1.3] - GO:0016787//hydrolase activity GO:0006629//lipid metabolic process gi|407264266|ref|XP_003945643.1|/0/PREDICTED: lipase member K-like isoform X2 [Mus musculus] 74454 1859 0.063333333 0.01 -2.662965013 Down 0.17409455 4933408J17Rik RIKEN cDNA 4933408J17 gene - - - - - 226169 5244 4.846666667 5.15 0.087579569 Up 0.174075746 Pprc1 "peroxisome proliferative activated receptor, gamma, coactivator-related 1" K17963|1|0.0|2469|mmu:226169|peroxisome proliferator-activated receptor gamma coactivator-related protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|124487055|ref|NP_001074683.1|/0/peroxisome proliferator-activated receptor gamma coactivator-related protein 1 [Mus musculus] 66114 1160 43.54666667 42.05333333 -0.050342131 Down 0.174075746 Dnajc30 DnaJ heat shock protein family (Hsp40) member C30 K19374|1|1e-85|319|mmu:66114|DnaJ homolog subfamily C member 30 - - - - 381823 3284 9.586666667 9.146666667 -0.067783194 Down 0.174075746 Apold1 apolipoprotein L domain containing 1 K14480|1|6e-33|145|tgu:100231048|apolipoprotein L;K14777|4|4e-29|133|gfr:102041563|ATP-dependent RNA helicase DDX47/RRP3 [EC:3.6.4.13] - - GO:0001775//cell activation;GO:0006950//response to stress;GO:0030856//regulation of epithelial cell differentiation gi|158186728|ref|NP_001103384.1|/1.21899e-86/apolipoprotein L domain-containing protein 1 [Mus musculus] 51786 5315 4.883333333 4.586666667 -0.090420195 Down 0.174075746 Cpsf2 cleavage and polyadenylation specific factor 2 K14402|1|0.0|1411|mmu:51786|cleavage and polyadenylation specificity factor subunit 2 GO:0005849//mRNA cleavage factor complex GO:0003676//nucleic acid binding;GO:0003824//catalytic activity GO:0008334//histone mRNA metabolic process;GO:0031124//mRNA 3'-end processing gi|625214802|ref|XP_007647923.1|/0/PREDICTED: cleavage and polyadenylation specificity factor subunit 2 isoform X1 [Cricetulus griseus] 15382 1768.2 39.41333333 40.90333333 0.053534649 Up 0.174075746 Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 K12741|1|3e-107|391|shr:100919352|heterogeneous nuclear ribonucleoprotein A1/A3 GO:0005681//spliceosomal complex;GO:0005856//cytoskeleton;GO:0031981//nuclear lumen;GO:0005681//spliceosomal complex;GO:0005856//cytoskeleton;GO:0031981//nuclear lumen;GO:0005681//spliceosomal complex;GO:0005856//cytoskeleton;GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0036094//small molecule binding;GO:0043566//structure-specific DNA binding;GO:0003723//RNA binding;GO:0036094//small molecule binding;GO:0043566//structure-specific DNA binding;GO:0003723//RNA binding;GO:0036094//small molecule binding;GO:0043566//structure-specific DNA binding "GO:0050658//RNA transport;GO:0000398//mRNA splicing, via spliceosome;GO:0006913//nucleocytoplasmic transport;GO:0050658//RNA transport;GO:0000398//mRNA splicing, via spliceosome;GO:0006913//nucleocytoplasmic transport;GO:0050658//RNA transport;GO:0000398//mRNA splicing, via spliceosome;GO:0006913//nucleocytoplasmic transport" "gi|148671985|gb|EDL03932.1|/3.98862e-115/mCG15678, isoform CRA_c, partial [Mus musculus]" 101739 2489.98 4.936666667 4.636666667 -0.090449221 Down 0.174075746 Psip1 PC4 and SFRS1 interacting protein 1 K16641|1|3e-43|179|amj:102569122|hepatoma-derived growth factor GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin GO:0001104//RNA polymerase II transcription cofactor activity;GO:0008134//transcription factor binding;GO:0043566//structure-specific DNA binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0008134//transcription factor binding;GO:0043566//structure-specific DNA binding GO:0006376//mRNA splice site selection;GO:0006950//response to stress;GO:0006366//transcription from RNA polymerase II promoter;GO:0006376//mRNA splice site selection;GO:0006950//response to stress;GO:0006366//transcription from RNA polymerase II promoter gi|568925923|ref|XP_006537605.1|/1.14194e-128/PREDICTED: PC4 and SFRS1-interacting protein isoform X1 [Mus musculus] 56364 4842.7 4.583333333 4.883333333 0.091469046 Up 0.174075746 Zmym3 "zinc finger, MYM-type 3" - - - - - 11569 4967.58 6.36 6.006666667 -0.08246216 Down 0.174056941 Aebp2 AE binding protein 2 K17452|1|2e-159|566|chx:102168985|zinc finger protein AEBP2 - - - gi|568944101|ref|XP_006506968.1|/1.20954e-151/PREDICTED: zinc finger protein AEBP2 isoform X1 [Mus musculus] 433256 3167 5.99 6.343333333 0.082685153 Up 0.174056941 Acsl5 acyl-CoA synthetase long-chain family member 5 K01897|1|0.0|1384|mmu:433256|long-chain acyl-CoA synthetase [EC:6.2.1.3] GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane GO:0032550;GO:0015645//fatty acid ligase activity GO:0006635//fatty acid beta-oxidation;GO:0032868//response to insulin;GO:0034285;GO:0006915//apoptotic process;GO:0010746;GO:0036314;GO:0009746;GO:0010866//regulation of triglyceride biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0031667//response to nutrient levels gi|58218988|ref|NP_082252.1|/0/long-chain-fatty-acid--CoA ligase 5 [Mus musculus] 76142 2524 45.42 43.94333333 -0.047683396 Down 0.174019331 Ppp1r14c "protein phosphatase 1, regulatory (inhibitor) subunit 14c" K17556|1|7e-49|198|mmu:76142|protein phosphatase 1 regulatory subunit 14C - GO:0004864//protein phosphatase inhibitor activity GO:0044092//negative regulation of molecular function;GO:0007154//cell communication gi|635077504|ref|XP_008005744.1|/1.89153e-52/PREDICTED: protein phosphatase 1 regulatory subunit 14C isoform X1 [Chlorocebus sabaeus] 329015 6340 14.83 14.19666667 -0.062966369 Down 0.173991124 Atg2a autophagy related 2A K17906|1|0.0|3608|mmu:329015|autophagy-related protein 2 - - GO:0044248 gi|37359928|dbj|BAC97942.1|/0/mKIAA0404 protein [Mus musculus] 243819 3812 40.98333333 42.45666667 0.050953779 Up 0.173953515 Ppp6r1 "protein phosphatase 6, regulatory subunit 1" K15499|1|0.0|1389|mmu:243819|serine/threonine-protein phosphatase 6 regulatory subunit 1 - - - gi|34536815|ref|NP_766482.2|/0/serine/threonine-protein phosphatase 6 regulatory subunit 1 [Mus musculus] 109637 1308 0.423333333 0.536666667 0.342232191 Up 0.173887698 Upk1a uroplakin 1A K17347|1|4e-118|427|mmu:109637|uroplakin-1 GO:0044459;GO:0031224//intrinsic component of membrane GO:0030246//carbohydrate binding GO:0030154//cell differentiation;GO:0016192//vesicle-mediated transport;GO:0007154//cell communication gi|58037127|ref|NP_081091.1|/3.56069e-117/uroplakin-1a [Mus musculus] 218518 3061 0.543333333 0.43 -0.337500899 Down 0.173887698 Marveld2 MARVEL (membrane-associating) domain containing 2 K17291|1|2e-89|332|mmu:218518|MARVEL domain-containing protein 2 GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex;GO:0043218//compact myelin;GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex;GO:0043218//compact myelin - GO:0050954//sensory perception of mechanical stimulus;GO:0034330;GO:0050954//sensory perception of mechanical stimulus;GO:0034330 gi|84370242|ref|NP_001033691.1|/0/MARVEL domain-containing protein 2 isoform 1 [Mus musculus] 56429 1636 39.85333333 41.31 0.051790664 Up 0.173878296 Dpt dermatopontin K02599|1|1e-11|73.9|bfo:BRAFLDRAFT_119094|Notch;K04365|2|7e-07|58.2|xtr:779570|B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] GO:0044421;GO:0031012//extracellular matrix - GO:0022610;GO:0030198//extracellular matrix organization;GO:0008283//cell proliferation gi|9789943|ref|NP_062733.1|/5.3987e-100/dermatopontin precursor [Mus musculus] 73331 1494 0.17 0.093333333 -0.86507042 Down 0.173868893 1700034P13Rik RIKEN cDNA 1700034P13 gene K11861|1|2e-87|285|phd:102334216|deubiquitinating protein VCIP135 [EC:3.4.19.12] - - - - 231712 2498 38.47 39.91333333 0.05313694 Up 0.173765467 Trafd1 TRAF type zinc finger domain containing 1 K03173|1|1e-07|61.6|tup:102473925|TNF receptor-associated factor 2 [EC:2.3.2.27];K03175|3|6e-06|55.8|tup:102482652|TNF receptor-associated factor 6 [EC:2.3.2.27];K09848|4|8e-06|55.5|isc:IscW_ISCW021630|TNF receptor-associated factor 4 GO:0044464;GO:0044464 GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0031348//negative regulation of defense response;GO:0010033//response to organic substance;GO:0031348//negative regulation of defense response;GO:0010033//response to organic substance gi|568937142|ref|XP_006530364.1|/0/PREDICTED: TRAF-type zinc finger domain-containing protein 1 isoform X3 [Mus musculus] 13385 3330 1.84 1.66 -0.148522525 Down 0.17369965 Dlg4 "discs, large homolog 4 (Drosophila)" K11828|1|0.0|1452|mmu:13385|discs large protein 4 GO:0008328//ionotropic glutamate receptor complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0005856//cytoskeleton;GO:0033267;GO:0030136//clathrin-coated vesicle;GO:0009898//cytoplasmic side of plasma membrane;GO:0005856//cytoskeleton;GO:0030139//endocytic vesicle;GO:0033267;GO:0008328//ionotropic glutamate receptor complex;GO:0009898//cytoplasmic side of plasma membrane;GO:0044327//dendritic spine head;GO:0030136//clathrin-coated vesicle;GO:0097060//synaptic membrane GO:0031811;GO:0031690//adrenergic receptor binding;GO:0019904//protein domain specific binding;GO:0019902//phosphatase binding;GO:0035254//glutamate receptor binding;GO:0031690//adrenergic receptor binding;GO:0019902//phosphatase binding;GO:0019904//protein domain specific binding;GO:0001609//G-protein coupled adenosine receptor activity;GO:0035254//glutamate receptor binding;GO:0031811 GO:0007626//locomotory behavior;GO:0051705;GO:0072578//neurotransmitter-gated ion channel clustering;GO:0048812//neuron projection morphogenesis;GO:0007625//grooming behavior;GO:0045838//positive regulation of membrane potential;GO:0048168//regulation of neuronal synaptic plasticity;GO:0035418//protein localization to synapse;GO:0044704//single-organism reproductive behavior;GO:0016050//vesicle organization;GO:0014070//response to organic cyclic compound;GO:0065003;GO:0010469//regulation of receptor activity;GO:0050905//neuromuscular process;GO:0035588;GO:0014070//response to organic cyclic compound;GO:0051705;GO:0007625//grooming behavior;GO:0010469//regulation of receptor activity;GO:0007611//learning or memory;GO:0006935//chemotaxis;GO:0007626//locomotory behavior;GO:0048812//neuron projection morphogenesis;GO:0035418//protein localization to synapse;GO:0006366//transcription from RNA polymerase II promoter;GO:0044704//single-organism reproductive behavior;GO:0065003;GO:0072578//neurotransmitter-gated ion channel clustering;GO:0050905//neuromuscular process;GO:0045838//positive regulation of membrane potential;GO:0016050//vesicle organization;GO:0048168//regulation of neuronal synaptic plasticity gi|6681195|ref|NP_031890.1|/0/disks large homolog 4 isoform 1 [Mus musculus] 100503704 1531 1.906666667 1.723333333 -0.145850866 Down 0.17369965 Gm16861 "predicted gene, 16861" K16867|1|6e-32|110|cge:100772569|NUDT16-like protein 1 - - - gi|344249481|gb|EGW05585.1|/4.81985e-31/Protein syndesmos [Cricetulus griseus] 56453 4250.83 16.37 15.75 -0.055702493 Down 0.173643236 Mbtps1 "membrane-bound transcription factor peptidase, site 1" K08653|1|0.0|2080|mmu:56453|membrane-bound transcription factor site-1 protease [EC:3.4.21.112] - - - "gi|148679654|gb|EDL11601.1|/0/membrane-bound transcription factor peptidase, site 1, isoform CRA_b, partial [Mus musculus]" 26400 3369.3 37.85 39.27333333 0.053256752 Up 0.173633834 Map2k7 mitogen-activated protein kinase kinase 7 K04431|1|0.0|719|mmu:26400|mitogen-activated protein kinase kinase 7 [EC:2.7.12.2] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0004708//MAP kinase kinase activity;GO:0032550;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0019902//phosphatase binding;GO:0004708//MAP kinase kinase activity;GO:0032550;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0019902//phosphatase binding;GO:0004708//MAP kinase kinase activity;GO:0032550;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0019902//phosphatase binding;GO:0004708//MAP kinase kinase activity;GO:0032550;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0019902//phosphatase binding;GO:0004708//MAP kinase kinase activity;GO:0032550;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0019902//phosphatase binding GO:0043065//positive regulation of apoptotic process;GO:0000187//activation of MAPK activity;GO:0051403//stress-activated MAPK cascade;GO:0043065//positive regulation of apoptotic process;GO:0000187//activation of MAPK activity;GO:0051403//stress-activated MAPK cascade;GO:0043065//positive regulation of apoptotic process;GO:0000187//activation of MAPK activity;GO:0051403//stress-activated MAPK cascade;GO:0043065//positive regulation of apoptotic process;GO:0000187//activation of MAPK activity;GO:0051403//stress-activated MAPK cascade;GO:0043065//positive regulation of apoptotic process;GO:0000187//activation of MAPK activity;GO:0051403//stress-activated MAPK cascade gi|110347549|ref|NP_001036022.1|/0/dual specificity mitogen-activated protein kinase kinase 7 isoform 1 [Mus musculus] 407823 7980 2.03 1.843333333 -0.139162748 Down 0.173624431 Baz2b "bromodomain adjacent to zinc finger domain, 2B" K15224|1|1e-115|422|lcm:102355413|bromodomain adjacent to zinc finger domain protein 2A - - - gi|62177117|ref|NP_001001182.2|/0/bromodomain adjacent to zinc finger domain protein 2B [Mus musculus] 11513 5937 1.926666667 2.12 0.137957273 Up 0.173624431 Adcy7 adenylate cyclase 7 K08047|1|0.0|1958|mmu:11513|adenylate cyclase 7 [EC:4.6.1.1] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0032550;GO:0043169//cation binding;GO:0016829//lyase activity;GO:0009975//cyclase activity;GO:0032550;GO:0043169//cation binding;GO:0016829//lyase activity;GO:0009975//cyclase activity;GO:0032550;GO:0043169//cation binding;GO:0016829//lyase activity;GO:0009975//cyclase activity;GO:0032550;GO:0043169//cation binding;GO:0016829//lyase activity;GO:0009975//cyclase activity GO:0045471//response to ethanol;GO:0045762//positive regulation of adenylate cyclase activity;GO:0007565//female pregnancy;GO:0007165//signal transduction;GO:0045471//response to ethanol;GO:0045762//positive regulation of adenylate cyclase activity;GO:0007565//female pregnancy;GO:0007165//signal transduction;GO:0045471//response to ethanol;GO:0045762//positive regulation of adenylate cyclase activity;GO:0007565//female pregnancy;GO:0007165//signal transduction;GO:0045471//response to ethanol;GO:0045762//positive regulation of adenylate cyclase activity;GO:0007565//female pregnancy;GO:0007165//signal transduction gi|83582788|ref|NP_001032813.1|/0/adenylate cyclase type 7 [Mus musculus] 14739 2815 2.006666667 1.82 -0.140862536 Down 0.173624431 S1pr2 sphingosine-1-phosphate receptor 2 K04292|1|5e-166|587|mmu:14739|sphingosine 1-phosphate receptor 2 GO:0031224//intrinsic component of membrane GO:0045125//bioactive lipid receptor activity GO:0007186//G-protein coupled receptor signaling pathway gi|45433562|ref|NP_034463.2|/4.18599e-165/sphingosine 1-phosphate receptor 2 [Mus musculus] 230996 2510 1.86 2.046666667 0.137973534 Up 0.173624431 9430015G10Rik RIKEN cDNA 9430015G10 gene - - - - gi|225543202|ref|NP_663532.2|/9.51093e-97/uncharacterized protein C1orf159 homolog precursor [Mus musculus] 100504715 6872 1.82 2.01 0.143257051 Up 0.173624431 Tmppe transmembrane protein with metallophosphoesterase domain K12309|1|0.0|671|cfr:102516561|beta-galactosidase [EC:3.2.1.23] - - - gi|317008614|ref|NP_001186931.1|/0/transmembrane protein with metallophosphoesterase domain [Mus musculus] 20713 3133 1.9 2.086666667 0.135200738 Up 0.173624431 Serpini1 "serine (or cysteine) peptidase inhibitor, clade I, member 1" K16643|1|1e-58|231|tup:102477375|glia-derived nexin - - - gi|6678091|ref|NP_033276.1|/0/neuroserpin precursor [Mus musculus] 65099 1893 2.106666667 1.916666667 -0.136362602 Down 0.173624431 Irak1bp1 interleukin-1 receptor-associated kinase 1 binding protein 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups" "GO:0006796//phosphate-containing compound metabolic process;GO:0006351//transcription, DNA-templated;GO:0006796//phosphate-containing compound metabolic process;GO:0006351//transcription, DNA-templated" gi|269847804|ref|NP_001161712.1|/1.47405e-125/interleukin-1 receptor-associated kinase 1-binding protein 1 isoform 2 [Mus musculus] 94040 11869 0.71 0.586666667 -0.275278002 Down 0.173568017 Clmn calmin K19326|1|1e-62|246|dre:567576|nesprin-1 GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424 GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0008283//cell proliferation;GO:0030030//cell projection organization;GO:0008283//cell proliferation;GO:0030030//cell projection organization;GO:0008283//cell proliferation;GO:0030030//cell projection organization;GO:0008283//cell proliferation;GO:0030030//cell projection organization;GO:0008283//cell proliferation;GO:0030030//cell projection organization;GO:0008283//cell proliferation;GO:0030030//cell projection organization;GO:0008283//cell proliferation;GO:0030030//cell projection organization gi|100816764|ref|NP_444385.2|/0/calmin isoform a [Mus musculus] 117591 3403 0.573333333 0.696666667 0.281094377 Up 0.173568017 Slc2a9 "solute carrier family 2 (facilitated glucose transporter), member 9" "K08146|1|2e-172|609|ngi:103734229|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 9" GO:0012505//endomembrane system;GO:0016021//integral component of membrane;GO:0012505//endomembrane system;GO:0016021//integral component of membrane;GO:0012505//endomembrane system;GO:0016021//integral component of membrane;GO:0012505//endomembrane system;GO:0016021//integral component of membrane - GO:0008645//hexose transport;GO:0006082//organic acid metabolic process;GO:0008645//hexose transport;GO:0006082//organic acid metabolic process;GO:0008645//hexose transport;GO:0006082//organic acid metabolic process;GO:0008645//hexose transport;GO:0006082//organic acid metabolic process "gi|156231035|ref|NP_001095885.1|/0/solute carrier family 2, facilitated glucose transporter member 9 isoform 3 [Mus musculus]" 100043332 1321 0.046666667 0.113333333 1.280107919 Up 0.173521005 Ankrd66 ankyrin repeat domain 66 K17593|1|3e-12|75.5|acs:100564447|ankyrin repeat domain-containing protein 42;K15503|3|3e-12|75.5|ccw:104693753|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B - - - - 75881 1152 0.05 0.12 1.263034406 Up 0.173521005 4930579K19Rik RIKEN cDNA 4930579K19 gene - - - - gi|148689039|gb|EDL20986.1|/1.26172e-59/mCG1032870 [Mus musculus] 654494 2654 0.12 0.05 -1.263034406 Down 0.173521005 Gm7337 DAZ interacting protein 1 pseudogene K16470|1|3e-119|429|rno:364475|zinc finger protein DZIP1 GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding GO:0032501//multicellular organismal process;GO:0010927 gi|187955390|gb|AAI47624.1|/0/Odam protein [Mus musculus] 13638 1225 0.046666667 0.113333333 1.280107919 Up 0.173521005 Efna3 ephrin A3 K05462|1|4e-118|427|rno:170901|ephrin-A GO:0031224//intrinsic component of membrane GO:0005102//receptor binding GO:0030182//neuron differentiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|117935036|ref|NP_034238.1|/3.25021e-117/ephrin-A3 precursor [Mus musculus] 70358 1216 0.046666667 0.113333333 1.280107919 Up 0.173521005 Steap1 six transmembrane epithelial antigen of the prostate 1 K14737|1|0.0|662|mmu:70358|metalloreductase STEAP1 [EC:1.16.1.-] GO:0030054//cell junction;GO:0031090//organelle membrane;GO:0016021//integral component of membrane GO:0043169//cation binding;GO:0022803//passive transmembrane transporter activity;GO:0003824//catalytic activity GO:0044765//single-organism transport;GO:0055080//cation homeostasis;GO:0044710;GO:0006091//generation of precursor metabolites and energy gi|74188352|dbj|BAE25828.1|/0/unnamed protein product [Mus musculus] 76574 2166 0.113333333 0.046666667 -1.280107919 Down 0.173521005 Mfsd2a major facilitator superfamily domain containing 2A K08824|1|2e-20|103|bfo:BRAFLDRAFT_90694|cyclin-dependent kinase-like [EC:2.7.11.22] GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization gi|227430371|ref|NP_083938.2|/0/sodium-dependent lysophosphatidylcholine symporter 1 [Mus musculus] 68505 2631 8.82 9.25 0.06867471 Up 0.173361164 Vps51 VPS51 GARP complex subunit K20296|1|0.0|1288|mmu:68505|vacuolar protein sorting-associated protein 51 - - - "gi|148701257|gb|EDL33204.1|/0/mCG11742, isoform CRA_b [Mus musculus]" 67179 2228 8.156666667 8.586666667 0.074118492 Up 0.173361164 Ccdc25 coiled-coil domain containing 25 K04989|1|2e-43|180|ggo:101123846|polycystin 1L3 - - - gi|625246380|ref|XP_007614445.1|/1.18193e-119/PREDICTED: coiled-coil domain-containing protein 25 isoform X2 [Cricetulus griseus] 211673 7042 9.143333333 8.713333333 -0.069495481 Down 0.173361164 Arfgef1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) K18442|1|0.0|3486|mmu:211673|brefeldin A-inhibited guanine nucleotide-exchange protein - - - gi|156231075|ref|NP_001095900.1|/0/brefeldin A-inhibited guanine nucleotide-exchange protein 1 [Mus musculus] 17880 6616.15 8.52 8.093333333 -0.074119415 Down 0.173361164 Myh11 "myosin, heavy polypeptide 11, smooth muscle" K10352|1|0.0|3231|mmu:17880|myosin heavy chain GO:0043292//contractile fiber;GO:0032432//actin filament bundle;GO:0016460//myosin II complex;GO:0043292//contractile fiber;GO:0032432//actin filament bundle;GO:0016460//myosin II complex GO:0008092//cytoskeletal protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005198//structural molecule activity GO:0085029//extracellular matrix assembly;GO:0048738//cardiac muscle tissue development;GO:0006936//muscle contraction;GO:0085029//extracellular matrix assembly;GO:0048738//cardiac muscle tissue development;GO:0006936//muscle contraction gi|50510675|dbj|BAD32323.1|/0/mKIAA0866 protein [Mus musculus] 69823 4371.01 9.086666667 9.513333333 0.066199773 Up 0.173361164 Fyttd1 forty-two-three domain containing 1 - GO:0016604//nuclear body;GO:0016604//nuclear body GO:0003723//RNA binding;GO:0003723//RNA binding GO:0006405//RNA export from nucleus;GO:0006405//RNA export from nucleus gi|226823218|ref|NP_001152821.1|/1.78405e-149/UAP56-interacting factor isoform 2 [Mus musculus] 22166 1051 38.17333333 39.56 0.051477256 Up 0.173351762 Txn1 thioredoxin 1 K03671|1|1e-43|179|mmu:22166|thioredoxin 1 - - - - 19385 852 42.55666667 43.94 0.046149716 Up 0.17330475 Ranbp1 RAN binding protein 1 K15306|1|1e-83|311|ngi:103742054|Ran-binding protein 1 GO:0005815//microtubule organizing center - GO:0006810//transport;GO:0007100//mitotic centrosome separation gi|74139696|dbj|BAE31699.1|/1.09727e-82/unnamed protein product [Mus musculus] 66278 1036 40.13333333 41.50333333 0.048426225 Up 0.173248336 Smim20 small integral membrane protein 20 - - - - gi|667306113|ref|XP_008582916.1|/5.72902e-37/PREDICTED: small integral membrane protein 20-like [Galeopterus variegatus] 13663 2197.36 40.68 42.05333333 0.04790048 Up 0.173248336 Ei24 etoposide induced 2.4 mRNA K10134|1|3e-169|598|mmu:13663|etoposide-induced 2.4 mRNA GO:0005635//nuclear envelope;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane - GO:0012502//induction of programmed cell death;GO:0016049//cell growth;GO:0042221//response to chemical;GO:0044248;GO:0012502//induction of programmed cell death;GO:0016049//cell growth;GO:0042221//response to chemical;GO:0044248 gi|74186207|dbj|BAE42899.1|/2.20974e-168/unnamed protein product [Mus musculus] 320191 12836 2.286666667 2.083333333 -0.134352387 Down 0.17314491 Hook3 hook microtubule tethering protein 3 K16536|1|0.0|1283|mmu:320191|protein HOOK3 - - - - 67099 2666 2.07 2.266666667 0.130941478 Up 0.17314491 Mettl21a methyltransferase like 21A K02357|1|2e-29|134|pale:102895576|elongation factor Ts;K18417|2|9e-08|62.0|myd:102756155|ERI1 exoribonuclease 2 [EC:3.1.-.-] GO:0031224//intrinsic component of membrane GO:0008276//protein methyltransferase activity GO:0006479//protein methylation "gi|148667787|gb|EDL00204.1|/4.5721e-113/RIKEN cDNA 2310038H17, isoform CRA_a, partial [Mus musculus]" 17196 2683.06 1.05 1.196666667 0.188632015 Up 0.173135507 Mbp myelin basic protein K17269|1|9e-143|510|mmu:17196|myelin basic protein GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043209//myelin sheath;GO:0033267;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043209//myelin sheath;GO:0033267;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043209//myelin sheath;GO:0033267;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043209//myelin sheath;GO:0033267;GO:0016020//membrane GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0019899//enzyme binding;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0008366//axon ensheathment;GO:0042221//response to chemical;GO:0007409//axonogenesis;GO:0008366//axon ensheathment;GO:0042221//response to chemical;GO:0007409//axonogenesis;GO:0008366//axon ensheathment;GO:0042221//response to chemical;GO:0007409//axonogenesis;GO:0008366//axon ensheathment;GO:0042221//response to chemical;GO:0007409//axonogenesis "gi|148677439|gb|EDL09386.1|/1.04271e-117/myelin basic protein, isoform CRA_e [Mus musculus]" 11867 1555 40.76333333 42.11666667 0.047119229 Up 0.1731073 Arpc1b "actin related protein 2/3 complex, subunit 1B" "K05757|1|0.0|748|mmu:11867|actin related protein 2/3 complex, subunit 1A/1B" GO:0015629//actin cytoskeleton - GO:0008064//regulation of actin polymerization or depolymerization gi|160837788|ref|NP_075631.2|/0/actin-related protein 2/3 complex subunit 1B [Mus musculus] 11552 3936 0.533333333 0.423333333 -0.333243408 Down 0.17306969 Adra2b "adrenergic receptor, alpha 2b" K04139|1|0.0|824|mmu:11552|adrenergic receptor alpha-2B GO:0031224//intrinsic component of membrane GO:1901338;GO:0004936//alpha-adrenergic receptor activity GO:0044703;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0045987//positive regulation of smooth muscle contraction;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0008217//regulation of blood pressure;GO:0000187//activation of MAPK activity;GO:0030182//neuron differentiation gi|46575786|ref|NP_033763.2|/0/alpha-2B adrenergic receptor [Mus musculus] 56506 736 0.42 0.526666667 0.326500825 Up 0.17306969 Cib2 calcium and integrin binding family member 2 K17259|1|9e-43|175|spu:756594|calcium and integrin-binding protein 1 - GO:0046872//metal ion binding GO:0055065//metal ion homeostasis;GO:0007166//cell surface receptor signaling pathway;GO:0007601//visual perception gi|9790085|ref|NP_062660.1|/4.63291e-94/calcium and integrin-binding family member 2 [Mus musculus] 192950 4914 0.516666667 0.41 -0.3336099 Down 0.17306969 Nacad NAC alpha domain containing K03626|1|4e-55|220|mmu:17938|nascent polypeptide-associated complex subunit alpha GO:0043231//intracellular membrane-bounded organelle - GO:0045184//establishment of protein localization gi|126116574|ref|NP_001075121.1|/0/NAC-alpha domain-containing protein 1 [Mus musculus] 12642 1365 0.44 0.553333333 0.330645312 Up 0.17306969 Ch25h cholesterol 25-hydroxylase K10223|1|0.0|640|mmu:12642|cholesterol 25-hydroxylase [EC:1.14.99.38] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0046914//transition metal ion binding;GO:0004497//monooxygenase activity GO:0006631//fatty acid metabolic process;GO:0016125//sterol metabolic process;GO:0006694//steroid biosynthetic process gi|6857769|ref|NP_034020.1|/0/cholesterol 25-hydroxylase [Mus musculus] 108897 2967 0.536666667 0.426666667 -0.330916878 Down 0.17306969 Aif1l allograft inflammatory factor 1-like K18617|1|8e-79|298|rno:362107|allograft inflammatory factor 1 GO:0005924//cell-substrate adherens junction;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0015629//actin cytoskeleton GO:0046872//metal ion binding;GO:0003779//actin binding - gi|21553105|ref|NP_660126.1|/7.06377e-78/allograft inflammatory factor 1-like [Mus musculus] 69126 418 36.58333333 35.24666667 -0.053699708 Down 0.173013276 1810022K09Rik RIKEN cDNA 1810022K09 gene - - - - gi|123778490|sp|Q0VG62.1|CH059_MOUSE/1.33223e-47/RecName: Full=Uncharacterized protein C8orf59 homolog 74106 3306 33.96333333 35.28 0.054872502 Up 0.172844033 Dcaf6 DDB1 and CUL4 associated factor 6 K11795|1|0.0|1675|mmu:74106|nuclear receptor interaction protein GO:0031461//cullin-RING ubiquitin ligase complex GO:0003713//transcription coactivator activity GO:0006366//transcription from RNA polymerase II promoter gi|254039594|ref|NP_083035.1|/0/DDB1- and CUL4-associated factor 6 [Mus musculus] 12469 2391 39.28666667 40.60666667 0.047676838 Up 0.172844033 Cct8 "chaperonin containing Tcp1, subunit 8 (theta)" K09500|1|0.0|1004|mmu:12469|T-complex protein 1 subunit theta GO:0005815//microtubule organizing center;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0032550;GO:0005515//protein binding GO:0044267//cellular protein metabolic process;GO:0035036//sperm-egg recognition gi|50510319|dbj|BAD32145.1|/0/mKIAA0002 protein [Mus musculus] 17685 3056 6.083333333 5.74 -0.083811321 Down 0.172834631 Msh2 mutS homolog 2 K08735|1|0.0|1806|mmu:17685|DNA mismatch repair protein MSH2 - - - gi|6678938|ref|NP_032654.1|/0/DNA mismatch repair protein Msh2 [Mus musculus] 21665 3217.99 6.59 6.25 -0.076422275 Down 0.172834631 Tdg thymine DNA glycosylase K03649|1|0.0|732|mmu:21665|TDG/mug DNA glycosylase family protein [EC:3.2.2.-] GO:0016604//nuclear body;GO:0016604//nuclear body "GO:0000700;GO:0003690//double-stranded DNA binding;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0032182//ubiquitin-like protein binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0000700;GO:0003690//double-stranded DNA binding;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0032182//ubiquitin-like protein binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" GO:0006281//DNA repair;GO:0043393//regulation of protein binding;GO:0035561//regulation of chromatin binding;GO:0006366//transcription from RNA polymerase II promoter;GO:0006281//DNA repair;GO:0043393//regulation of protein binding;GO:0035561//regulation of chromatin binding;GO:0006366//transcription from RNA polymerase II promoter gi|166706899|ref|NP_766140.2|/0/G/T mismatch-specific thymine DNA glycosylase isoform 2 [Mus musculus] 12226 5010 5.666666667 6.003333333 0.083263435 Up 0.172834631 Btg1 "B cell translocation gene 1, anti-proliferative" K14443|1|9e-96|346|cjc:100405025|protein Tob/BTG GO:0043231//intracellular membrane-bounded organelle "GO:0000989//transcription factor activity, transcription factor binding;GO:0019899//enzyme binding" "GO:0001525//angiogenesis;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0008213;GO:0006915//apoptotic process;GO:0045445//myoblast differentiation;GO:0030858//positive regulation of epithelial cell differentiation;GO:0048870//cell motility;GO:0044093;GO:0007281//germ cell development;GO:0048232//male gamete generation;GO:0006950//response to stress;GO:0016049//cell growth;GO:0009725//response to hormone" "gi|119617872|gb|EAW97466.1|/8.94137e-108/B-cell translocation gene 1, anti-proliferative, isoform CRA_a, partial [Homo sapiens]" 66367 2181.42 38.26 39.56333333 0.048327109 Up 0.172759412 2310022A10Rik RIKEN cDNA 2310022A10 gene K17868|1|4e-08|63.2|tsp:Tsp_02631|diphthine methyl ester acylhydrolase [EC:3.1.1.97] - - - gi|170650651|ref|NP_780316.3|/0/uncharacterized protein C19orf47 homolog isoform 1 [Mus musculus] 207212 10250 14.33333333 13.73 -0.062042534 Down 0.172731205 Arhgef17 Rho guanine nucleotide exchange factor (GEF) 17 K16727|1|3e-35|155|ngi:103731950|Rho guanine nucleotide exchange factor 10 - - - gi|124487439|ref|NP_001074585.1|/0/rho guanine nucleotide exchange factor 17 [Mus musculus] 19262 3501 15.32666667 15.92666667 0.055400388 Up 0.172731205 Ptpra "protein tyrosine phosphatase, receptor type, A" K18032|1|0.0|1560|mmu:19262|receptor-type tyrosine-protein phosphatase A [EC:3.1.3.48] GO:0031224//intrinsic component of membrane;GO:0043227//membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043227//membrane-bounded organelle GO:0005515//protein binding;GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding;GO:0004721//phosphoprotein phosphatase activity GO:0007417//central nervous system development;GO:0006470//protein dephosphorylation;GO:0045687//positive regulation of glial cell differentiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007417//central nervous system development;GO:0006470//protein dephosphorylation;GO:0045687//positive regulation of glial cell differentiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|255304936|ref|NP_033006.2|/0/receptor-type tyrosine-protein phosphatase alpha isoform 1 precursor [Mus musculus] 22004 2575 14.03 13.43 -0.063055704 Down 0.172731205 Tpm2 "tropomyosin 2, beta" K10374|1|2e-94|350|cfr:102505904|tropomyosin 2 GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament;GO:0005865//striated muscle thin filament GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity GO:0009118//regulation of nucleoside metabolic process;GO:0006936//muscle contraction;GO:0009118//regulation of nucleoside metabolic process;GO:0003012//muscle system process;GO:0009987//cellular process;GO:0006936//muscle contraction gi|66730475|ref|NP_001019516.1|/9.4594e-87/tropomyosin beta chain isoform Tpm2.1sm/cy [Rattus norvegicus] 238384 2092 0.056666667 0.13 1.197939378 Up 0.172702997 Slc24a4 "solute carrier family 24 (sodium/potassium/calcium exchanger), member 4" "K13752|1|0.0|1097|cge:100752949|solute carrier family 24 (sodium/potassium/calcium exchanger), member 4" - - - - 22784 2006 0.053333333 0.12 1.169925001 Up 0.172702997 Slc30a3 "solute carrier family 30 (zinc transporter), member 3" "K14690|1|0.0|731|mmu:22784|solute carrier family 30 (zinc transporter), member 3" GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle;GO:0005768//endosome;GO:0042995//cell projection GO:0015075//ion transmembrane transporter activity GO:0009636//response to toxic substance;GO:0000041//transition metal ion transport;GO:0032119//sequestering of zinc ion "gi|148705386|gb|EDL37333.1|/0/solute carrier family 30 (zinc transporter), member 3, isoform CRA_b, partial [Mus musculus]" 103841 3117.92 40.54333333 41.83333333 0.045188251 Up 0.172693595 Cuedc1 CUE domain containing 1 - - - - gi|285402518|ref|NP_001165570.1|/2.23362e-164/CUE domain-containing protein 1 isoform 2 [Mus musculus] 56516 5218.75 33.33666667 34.62666667 0.054773657 Up 0.172693595 Rbms2 "RNA binding motif, single stranded interacting protein 2" K13088|1|3e-22|111|ola:101172398|ELAV-like protein 1;K13208|2|6e-22|110|bfo:BRAFLDRAFT_92208|ELAV like protein 2/3/4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding - "gi|84872203|ref|NP_062685.2|/0/RNA-binding motif, single-stranded-interacting protein 2 isoform a [Mus musculus]" 59013 2242 35.72666667 37.01333333 0.051043752 Up 0.172693595 Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 K12898|1|0.0|778|cge:100769493|heterogeneous nuclear ribonucleoprotein F/H GO:0005681//spliceosomal complex;GO:0005856//cytoskeleton;GO:0031981//nuclear lumen GO:0008187//poly-pyrimidine tract binding;GO:0036094//small molecule binding GO:0000377 "gi|148701752|gb|EDL33699.1|/0/heterogeneous nuclear ribonucleoprotein H1, isoform CRA_b, partial [Mus musculus]" 70911 2723 0.7 0.58 -0.271302022 Down 0.172684193 Phyhipl phytanoyl-CoA hydroxylase interacting protein-like - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|242397483|ref|NP_848736.2|/0/phytanoyl-CoA hydroxylase-interacting protein-like isoform 1 [Mus musculus] 76367 4413 0.716666667 0.593333333 -0.272459419 Down 0.172684193 Trp53rkb transformation related protein 53 regulating kinase B K08851|1|2e-111|407|mmu:76367|TP53 regulating kinase and related kinases [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004672//protein kinase activity;GO:0005515//protein binding GO:0008610//lipid biosynthetic process;GO:0006464//cellular protein modification process gi|568918806|ref|XP_006500434.1|/9.80503e-119/PREDICTED: TP53-regulating kinase isoform X1 [Mus musculus] 114249 4337 0.27 0.183333333 -0.558490289 Down 0.172665388 Npnt nephronectin K06824|1|0.0|1030|mmu:114249|nephronectin GO:0008305//integrin complex;GO:0005578//proteinaceous extracellular matrix;GO:0043292//contractile fiber;GO:0008305//integrin complex;GO:0005578//proteinaceous extracellular matrix;GO:0043292//contractile fiber;GO:0008305//integrin complex;GO:0005578//proteinaceous extracellular matrix;GO:0043292//contractile fiber;GO:0008305//integrin complex;GO:0005578//proteinaceous extracellular matrix;GO:0043292//contractile fiber;GO:0008305//integrin complex;GO:0005578//proteinaceous extracellular matrix;GO:0043292//contractile fiber GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0005102//receptor binding;GO:0046872//metal ion binding GO:0001649//osteoblast differentiation;GO:0010692;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0060004//reflex;GO:0010810//regulation of cell-substrate adhesion;GO:0034612//response to tumor necrosis factor;GO:0008104//protein localization;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006939//smooth muscle contraction;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043062//extracellular structure organization;GO:0043410//positive regulation of MAPK cascade;GO:0001649//osteoblast differentiation;GO:0010692;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0060004//reflex;GO:0010810//regulation of cell-substrate adhesion;GO:0034612//response to tumor necrosis factor;GO:0008104//protein localization;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006939//smooth muscle contraction;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043062//extracellular structure organization;GO:0043410//positive regulation of MAPK cascade;GO:0001649//osteoblast differentiation;GO:0010692;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0060004//reflex;GO:0010810//regulation of cell-substrate adhesion;GO:0034612//response to tumor necrosis factor;GO:0008104//protein localization;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006939//smooth muscle contraction;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043062//extracellular structure organization;GO:0043410//positive regulation of MAPK cascade;GO:0001649//osteoblast differentiation;GO:0010692;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0060004//reflex;GO:0010810//regulation of cell-substrate adhesion;GO:0034612//response to tumor necrosis factor;GO:0008104//protein localization;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006939//smooth muscle contraction;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043062//extracellular structure organization;GO:0043410//positive regulation of MAPK cascade;GO:0001649//osteoblast differentiation;GO:0010692;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0060004//reflex;GO:0010810//regulation of cell-substrate adhesion;GO:0034612//response to tumor necrosis factor;GO:0008104//protein localization;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006939//smooth muscle contraction;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043062//extracellular structure organization;GO:0043410//positive regulation of MAPK cascade gi|74182577|dbj|BAE34649.1|/0/unnamed protein product [Mus musculus] 381067 4541 0.536666667 0.43 -0.319689623 Down 0.172627778 Zfp229 zinc finger protein 229 K09228|1|0.0|1536|mmu:381067|KRAB domain-containing zinc finger protein - - - gi|257743035|ref|NP_001158148.1|/0/zinc finger protein 229 [Mus musculus] 67367 3809 3.373333333 3.623333333 0.10314265 Up 0.172618376 Paxbp1 PAX3 and PAX7 binding protein 1 K13211|1|0.0|1428|mmu:67367|GC-rich sequence DNA-binding factor GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding GO:0014841//skeletal muscle satellite cell proliferation;GO:0008284//positive regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0016571//histone methylation "gi|148671893|gb|EDL03840.1|/0/mCG115613, isoform CRA_b, partial [Mus musculus]" 211986 2971 3.703333333 3.453333333 -0.100834814 Down 0.172618376 Tmem18 transmembrane protein 18 - GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane GO:0003676//nucleic acid binding GO:0048870//cell motility;GO:0010467//gene expression gi|157951600|ref|NP_742046.2|/7.60877e-56/transmembrane protein 18 [Mus musculus] 100310872 4978 4.49 4.783333333 0.091300886 Up 0.172618376 Dynlt1a dynein light chain Tctex-type 1A K10420|1|2e-59|234|ocu:100339491|dynein light chain Tctex-type 1 GO:0043231//intracellular membrane-bounded organelle;GO:0030286//dynein complex GO:0005515//protein binding;GO:0003774//motor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0031175//neuron projection development;GO:0006886//intracellular protein transport;GO:0040001//establishment of mitotic spindle localization;GO:0010721//negative regulation of cell development;GO:0019048//modulation by virus of host morphology or physiology;GO:0000087//mitotic M phase gi|655844243|ref|XP_002715025.2|/1.70221e-58/PREDICTED: dynein light chain Tctex-type 1 [Oryctolagus cuniculus] 228850 8390 4.713333333 5 0.085180381 Up 0.172618376 Ralgapb "Ral GTPase activating protein, beta subunit (non-catalytic)" - - - - gi|597955362|ref|NP_001278066.1|/0/ral GTPase-activating protein subunit beta isoform a [Mus musculus] 54352 2421 4.386666667 4.68 0.093383447 Up 0.172618376 Irx5 Iroquois related homeobox 5 (Drosophila) K19383|1|3e-08|63.5|soc:105204813|homeobox protein TGIF1;K19553|3|1e-07|61.2|crg:105320634|homeobox protein TGIF2 - GO:0003677//DNA binding "GO:0048704//embryonic skeletal system morphogenesis;GO:0050789;GO:0003407//neural retina development;GO:0003008;GO:0048469//cell maturation;GO:0006351//transcription, DNA-templated" "gi|148679139|gb|EDL11086.1|/0/Iroquois related homeobox 5 (Drosophila), partial [Mus musculus]" 26889 6432 3.426666667 3.68 0.102899908 Up 0.172618376 Cln8 "ceroid-lipofuscinosis, neuronal 8" K12360|1|6e-149|532|mmu:26889|ceroid-lipofuscinosis neuronal protein 8 GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane - GO:0043086//negative regulation of catalytic activity;GO:0016125//sterol metabolic process;GO:0050879//multicellular organismal movement;GO:0051705;GO:0043010//camera-type eye development;GO:0007612//learning;GO:0006665//sphingolipid metabolic process;GO:0007033//vacuole organization;GO:0032535//regulation of cellular component size;GO:0006915//apoptotic process;GO:0045104//intermediate filament cytoskeleton organization;GO:0006796//phosphate-containing compound metabolic process;GO:0007601//visual perception;GO:0030163//protein catabolic process;GO:0007005//mitochondrion organization;GO:0051933;GO:0021522//spinal cord motor neuron differentiation;GO:0006979//response to oxidative stress;GO:0050905//neuromuscular process;GO:0008344//adult locomotory behavior gi|6753452|ref|NP_036130.1|/5.19307e-148/protein CLN8 [Mus musculus] 70355 3787.17 4.763333333 4.473333333 -0.090621245 Down 0.172618376 Gprc5c "G protein-coupled receptor, family C, group 5, member C" K04620|1|0.0|796|mmu:70355|G protein-coupled receptor family C group 5 member C GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity;GO:0005102//receptor binding;GO:0004888//transmembrane signaling receptor activity;GO:0005102//receptor binding;GO:0004888//transmembrane signaling receptor activity;GO:0005102//receptor binding GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway gi|160333233|ref|NP_671750.2|/0/G-protein coupled receptor family C group 5 member C isoform b precursor [Mus musculus] 11566 2553 3.613333333 3.36 -0.104869118 Down 0.172618376 Adss "adenylosuccinate synthetase, non muscle" K01939|1|0.0|924|mmu:11566|adenylosuccinate synthase [EC:6.3.4.4] GO:0016020//membrane;GO:0044424 "GO:0032550;GO:0046872//metal ion binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds" GO:0006167//AMP biosynthetic process;GO:0009154//purine ribonucleotide catabolic process;GO:0009066 gi|31560737|ref|NP_031448.2|/0/adenylosuccinate synthetase isozyme 2 [Mus musculus] 74841 4711 4.75 5.043333333 0.086450068 Up 0.172618376 Usp38 ubiquitin specific peptidase 38 K11854|1|0.0|1967|mmu:74841|ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12] - "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019941//modification-dependent protein catabolic process gi|37360592|dbj|BAC98274.1|/0/mKIAA1891 protein [Mus musculus] 217369 1703 0.096666667 0.173333333 0.842458723 Up 0.172599571 Uts2r urotensin 2 receptor K04241|1|0.0|648|mmu:217369|urotensin 2 receptor - - - - 431706 2117 0.173333333 0.096666667 -0.842458723 Down 0.172599571 Zfp457 zinc finger protein 457 K09228|1|0.0|1378|mmu:431706|KRAB domain-containing zinc finger protein - GO:0046872//metal ion binding - gi|110665714|ref|NP_001003666.2|/0/zinc finger protein 457 [Mus musculus] 230868 2017 0.103333333 0.183333333 0.827163403 Up 0.172599571 Igsf21 "immunoglobulin superfamily, member 21" K17341|1|4e-09|65.9|mmu:665700|hemicentin;K06255|5|6e-08|62.0|cjc:100413695|heparan sulfate proteoglycan 2 (perlecan) - - - gi|38348466|ref|NP_941012.1|/0/immunoglobulin superfamily member 21 precursor [Mus musculus] 19823 1232 40.13333333 38.85333333 -0.04676261 Down 0.172590169 Rnf7 ring finger protein 7 K10611|1|5e-58|227|tup:102492378|RING-box protein 2 - - - gi|947316332|ref|XP_014448678.1|/3.80822e-57/PREDICTED: RING-box protein 2 [Tupaia chinensis] 216363 2690 39.39 38.11333333 -0.047533627 Down 0.172590169 Rab3ip RAB3A interacting protein K16779|1|0.0|800|mmu:216363|Rab-3A-interacting protein GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0030864//cortical actin cytoskeleton;GO:0031252//cell leading edge GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0019899//enzyme binding GO:0010927;GO:0045184//establishment of protein localization;GO:0034613//cellular protein localization gi|51556219|ref|NP_001003950.1|/0/rab-3A-interacting protein [Mus musculus] 22376 2094 3.143333333 2.913333333 -0.109624491 Down 0.172571364 Was Wiskott-Aldrich syndrome K05747|1|6e-153|543|mmu:22376|Wiskott-Aldrich syndrome protein GO:0005856//cytoskeleton;GO:0012505//endomembrane system GO:0005515//protein binding;GO:0030695//GTPase regulator activity GO:0044765//single-organism transport;GO:0046649//lymphocyte activation;GO:0065003;GO:0006928//movement of cell or subcellular component;GO:0008154//actin polymerization or depolymerization gi|6678581|ref|NP_033541.1|/4.88799e-152/wiskott-Aldrich syndrome protein homolog [Mus musculus] 213068 2931 3.186666667 2.953333333 -0.109703919 Down 0.172571364 Tmem71 transmembrane protein 71 K19753|1|5e-28|129|ccw:104692632|protein TilB GO:0031224//intrinsic component of membrane - - gi|27369716|ref|NP_766102.1|/4.28086e-144/transmembrane protein 71 [Mus musculus] 68968 6384 3.003333333 2.773333333 -0.114943578 Down 0.172571364 Cdan1 "congenital dyserythropoietic anemia, type I (human)" K19531|1|0.0|1968|mmu:68968|codanin-1 - - - gi|124430553|ref|NP_081167.2|/0/codanin-1 [Mus musculus] 214642 4898 3.206666667 2.973333333 -0.108993184 Down 0.172571364 Cped1 cadherin-like and PC-esterase domain containing 1 - - - - gi|124486851|ref|NP_001074820.1|/0/cadherin-like and PC-esterase domain-containing protein 1 [Mus musculus] 19700 1603 2.75 2.976666667 0.114266056 Up 0.172571364 Rem1 rad and gem related GTP binding protein 1 K07847|1|9e-135|483|mmu:19700|Rad and Gem related GTP binding protein 1 - - - - 216445 1811 3.17 2.943333333 -0.107031903 Down 0.172571364 Arhgap9 Rho GTPase activating protein 9 K01556|1|4e-72|275|xtr:100485536|kynureninase [EC:3.7.1.3];K20315|2|6e-35|152|hst:105183805|Rho GTPase-activating protein 21/23 GO:0044464 GO:0008047//enzyme activator activity;GO:0008289//lipid binding GO:0043087//regulation of GTPase activity;GO:0043087//regulation of GTPase activity;GO:0007154//cell communication gi|551411363|ref|NP_001272714.1|/0/rho GTPase-activating protein 9 isoform 1 [Mus musculus] 65945 4496.98 34.84333333 33.57333333 -0.053566866 Down 0.172505547 Clstn1 calsyntenin 1 K16507|1|6e-12|76.6|spu:580282|protocadherin-16/23;K04601|5|6e-12|76.6|bfo:BRAFLDRAFT_130073|cadherin EGF LAG seven-pass G-type receptor 2 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0097060//synaptic membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0097060//synaptic membrane GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion;GO:0007267//cell-cell signaling;GO:0006875//cellular metal ion homeostasis;GO:0016337//single organismal cell-cell adhesion;GO:0007267//cell-cell signaling;GO:0006875//cellular metal ion homeostasis gi|50510703|dbj|BAD32337.1|/0/mKIAA0911 protein [Mus musculus] 212448 5644 0.186666667 0.273333333 0.550197083 Up 0.172449133 9330159F19Rik RIKEN cDNA 9330159F19 gene - - - - gi|242117990|ref|NP_001156009.1|/0/uncharacterized protein KIAA0408 homolog [Mus musculus] 12021 5448 0.2 0.293333333 0.552541023 Up 0.172449133 Bard1 BRCA1 associated RING domain 1 K10683|1|0.0|1461|mmu:12021|BRCA1-associated RING domain protein 1 GO:0000152//nuclear ubiquitin ligase complex GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination;GO:0016310//phosphorylation;GO:0006611//protein export from nucleus;GO:0006915//apoptotic process;GO:0006259//DNA metabolic process;GO:0048232//male gamete generation;GO:0033554//cellular response to stress "gi|148667842|gb|EDL00259.1|/0/BRCA1 associated RING domain 1, isoform CRA_a, partial [Mus musculus]" 71325 2066 0.293333333 0.2 -0.552541023 Down 0.172449133 Tchhl1 trichohyalin-like 1 K19607|1|4e-14|82.8|ccw:104686354|X-linked retinitis pigmentosa GTPase regulator - GO:0046872//metal ion binding - gi|153791448|ref|NP_082038.2|/0/trichohyalin-like protein 1 [Mus musculus] 103765 1370 1.24 1.396666667 0.171647623 Up 0.172430328 Tmem17 transmembrane protein 17 K19384|1|8e-72|273|mmu:103765|transmembrane protein 17 GO:0031090//organelle membrane;GO:0044425;GO:0035869//ciliary transition zone - GO:0007166//cell surface receptor signaling pathway;GO:0010927 gi|23956402|ref|NP_705824.1|/7.05651e-71/transmembrane protein 17 [Mus musculus] 72020 4835 1.246666667 1.403333333 0.170781963 Up 0.172430328 Zfp654 zinc finger protein 654 K06230|1|4e-06|57.4|bmy:Bm1_06540|zinc finger protein GLI3;K09228|2|5e-06|57.0|bom:102265931|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|755554062|ref|XP_006522649.2|/0/PREDICTED: zinc finger protein 654 isoform X2 [Mus musculus] 14056 2665 1.27 1.426666667 0.167819799 Up 0.172430328 Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit K11430|1|0.0|1394|mmu:14056|histone-lysine N-methyltransferase EZH2 [EC:2.1.1.43] - - - - 100042856 8843 1.443333333 1.283333333 -0.169508579 Down 0.172430328 Gm4070 predicted gene 4070 K06551|1|3e-74|284|xtr:101733039|signal-regulatory protein alpha/beta1/gamma;K12797|2|1e-16|93.2|myb:102249258|caspase recruitment domain-containing protein 6 - - - - 69221 461 9.133333333 8.713333333 -0.067916752 Down 0.172420926 2410006H16Rik RIKEN cDNA 2410006H16 gene - - - - "gi|148678410|gb|EDL10357.1|/5.97508e-40/mCG1044749, isoform CRA_a, partial [Mus musculus]" 18105 3892.04 8.376666667 8.796666667 0.070580679 Up 0.172420926 Nqo2 "NAD(P)H dehydrogenase, quinone 2" K08071|1|9e-121|437|mmu:18105|ribosyldihydronicotinamide dehydrogenase (quinone) [EC:1.10.5.1] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0003824//catalytic activity GO:0044710;GO:0007611//learning or memory;GO:0044710;GO:0007611//learning or memory;GO:0044710;GO:0007611//learning or memory;GO:0044710;GO:0007611//learning or memory gi|9937970|ref|NP_064678.1|/7.72891e-120/ribosyldihydronicotinamide dehydrogenase [quinone] isoform 1 [Mus musculus] 56310 1220 35.64666667 36.91 0.050244562 Up 0.172402121 Gps2 G protein pathway suppressor 2 K15307|1|5e-159|563|mmu:56310|G protein pathway suppressor 2 - - - - 74846 995 0.106666667 0.186666667 0.807354922 Up 0.172326902 4930405A21Rik RIKEN cDNA 4930405A21 gene - - - - - 18222 3386.66 14.54 13.95333333 -0.059417458 Down 0.1723175 Numb numb homolog (Drosophila) K06057|1|0.0|558|mmu:18222|numb GO:0005768//endosome;GO:0019898//extrinsic component of membrane;GO:0044459;GO:0005768//endosome;GO:0019898//extrinsic component of membrane;GO:0044459;GO:0005768//endosome;GO:0019898//extrinsic component of membrane;GO:0044459;GO:0005768//endosome;GO:0019898//extrinsic component of membrane;GO:0044459;GO:0005768//endosome;GO:0019898//extrinsic component of membrane;GO:0044459;GO:0005768//endosome;GO:0019898//extrinsic component of membrane;GO:0044459 GO:0050839//cell adhesion molecule binding;GO:0050839//cell adhesion molecule binding;GO:0050839//cell adhesion molecule binding;GO:0050839//cell adhesion molecule binding;GO:0050839//cell adhesion molecule binding;GO:0050839//cell adhesion molecule binding GO:0007219//Notch signaling pathway;GO:0031346//positive regulation of cell projection organization;GO:0010720//positive regulation of cell development;GO:0030858//positive regulation of epithelial cell differentiation;GO:0021846//cell proliferation in forebrain;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0021537//telencephalon development;GO:0045216//cell-cell junction organization;GO:0007219//Notch signaling pathway;GO:0031346//positive regulation of cell projection organization;GO:0010720//positive regulation of cell development;GO:0030858//positive regulation of epithelial cell differentiation;GO:0021846//cell proliferation in forebrain;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0021537//telencephalon development;GO:0045216//cell-cell junction organization;GO:0007219//Notch signaling pathway;GO:0031346//positive regulation of cell projection organization;GO:0010720//positive regulation of cell development;GO:0030858//positive regulation of epithelial cell differentiation;GO:0021846//cell proliferation in forebrain;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0021537//telencephalon development;GO:0045216//cell-cell junction organization;GO:0007219//Notch signaling pathway;GO:0031346//positive regulation of cell projection organization;GO:0010720//positive regulation of cell development;GO:0030858//positive regulation of epithelial cell differentiation;GO:0021846//cell proliferation in forebrain;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0021537//telencephalon development;GO:0045216//cell-cell junction organization;GO:0007219//Notch signaling pathway;GO:0031346//positive regulation of cell projection organization;GO:0010720//positive regulation of cell development;GO:0030858//positive regulation of epithelial cell differentiation;GO:0021846//cell proliferation in forebrain;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0021537//telencephalon development;GO:0045216//cell-cell junction organization;GO:0007219//Notch signaling pathway;GO:0031346//positive regulation of cell projection organization;GO:0010720//positive regulation of cell development;GO:0030858//positive regulation of epithelial cell differentiation;GO:0021846//cell proliferation in forebrain;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0021537//telencephalon development;GO:0045216//cell-cell junction organization gi|755542272|ref|XP_006515635.2|/0/PREDICTED: protein numb homolog isoform X3 [Mus musculus] 13680 2580 14.26 14.85333333 0.05881275 Up 0.1723175 Ddx19a DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a K18655|1|0.0|907|mmu:13680|ATP-dependent RNA helicase DDX19/DBP5 [EC:3.6.4.13] GO:0005635//nuclear envelope "GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled" GO:0012502//induction of programmed cell death;GO:0010038//response to metal ion;GO:0050658//RNA transport;GO:0045184//establishment of protein localization gi|170932536|ref|NP_031942.2|/0/ATP-dependent RNA helicase DDX19A [Mus musculus] 329763 1665 0.713333333 0.596666667 -0.257651209 Down 0.172261085 Gm5105 predicted gene 5105 - - - - "gi|148680164|gb|EDL12111.1|/1.08246e-79/hypothetical protein D830013H12, partial [Mus musculus]" 319430 3429 0.583333333 0.7 0.263034406 Up 0.172261085 C5ar2 complement component 5a receptor 2 K04171|1|5e-173|611|mmu:319430|G protein-coupled receptor 77 GO:0031224//intrinsic component of membrane;GO:0016323//basolateral plasma membrane;GO:0031224//intrinsic component of membrane;GO:0016323//basolateral plasma membrane GO:0004942//anaphylatoxin receptor activity;GO:0004942//anaphylatoxin receptor activity GO:0032675//regulation of interleukin-6 production;GO:0002689//negative regulation of leukocyte chemotaxis;GO:0001818//negative regulation of cytokine production;GO:0007166//cell surface receptor signaling pathway;GO:0032677;GO:0032675//regulation of interleukin-6 production;GO:0002689//negative regulation of leukocyte chemotaxis;GO:0001818//negative regulation of cytokine production;GO:0007166//cell surface receptor signaling pathway;GO:0032677 gi|74213563|dbj|BAE35590.1|/2.67845e-177/unnamed protein product [Mus musculus] 14864 1202 0.133333333 0.06 -1.152003093 Down 0.172185866 Gstm3 "glutathione S-transferase, mu 3" K00799|1|2e-126|454|mmu:14864|glutathione S-transferase [EC:2.5.1.18] - - - - 74361 2037 0.06 0.133333333 1.152003093 Up 0.172185866 4931429L15Rik RIKEN cDNA 4931429L15 gene - - - - "gi|148693742|gb|EDL25689.1|/0/RIKEN cDNA 4931429L15, isoform CRA_b, partial [Mus musculus]" 100503175 841 0.126666667 0.056666667 -1.160464672 Down 0.172185866 Gm19582 "predicted gene, 19582" - - - - - 13437 1826.4 39.15666667 37.93 -0.045918585 Down 0.172148257 Dnpep aspartyl aminopeptidase K01267|1|0.0|947|mmu:13437|aspartyl aminopeptidase [EC:3.4.11.21] GO:0044424;GO:0044424 "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0019538//protein metabolic process gi|161016822|ref|NP_001104301.1|/0/aspartyl aminopeptidase isoform a [Mus musculus] 108143 1240.2 36.66 35.43 -0.04923532 Down 0.172148257 Taf9 TATA-box binding protein associated factor 9 K14535|1|1e-135|485|mmu:108143|transcription initiation factor TFIID subunit 9 GO:0044665//MLL1/2 complex;GO:0070461//SAGA-type complex;GO:0005667//transcription factor complex;GO:0016604//nuclear body;GO:0030529//intracellular ribonucleoprotein complex;GO:0044665//MLL1/2 complex;GO:0070461//SAGA-type complex;GO:0005667//transcription factor complex;GO:0016604//nuclear body;GO:0030529//intracellular ribonucleoprotein complex "GO:0032550;GO:0003712//transcription cofactor activity;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0000975//regulatory region DNA binding;GO:0008134//transcription factor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0008080//N-acetyltransferase activity;GO:0032550;GO:0003712//transcription cofactor activity;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0000975//regulatory region DNA binding;GO:0008134//transcription factor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0008080//N-acetyltransferase activity" GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0006796//phosphate-containing compound metabolic process;GO:0031330;GO:0034097//response to cytokine;GO:0016049//cell growth;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0006796//phosphate-containing compound metabolic process;GO:0031330;GO:0034097//response to cytokine;GO:0016049//cell growth;GO:0016573//histone acetylation gi|18079237|ref|NP_081415.1|/1.03235e-134/transcription initiation factor TFIID subunit 9 [Mus musculus] 381546 1295 0.19 0.276666667 0.542149417 Up 0.172091842 Ccdc24 coiled-coil domain containing 24 - - - - "gi|148698592|gb|EDL30539.1|/3.8735e-124/mCG8864, isoform CRA_c [Mus musculus]" 19348 3473 2.323333333 2.53 0.12294123 Up 0.172073038 Kif20a kinesin family member 20A K10402|1|0.0|1536|mmu:19348|kinesin family member 20 GO:0015630//microtubule cytoskeleton;GO:0031981//nuclear lumen;GO:0015630//microtubule cytoskeleton;GO:0031981//nuclear lumen GO:0032550;GO:0019900//kinase binding;GO:0003774//motor activity;GO:0032550;GO:0019900//kinase binding;GO:0003774//motor activity GO:0000278//mitotic cell cycle;GO:0006810//transport;GO:0045184//establishment of protein localization;GO:0000226//microtubule cytoskeleton organization;GO:0006928//movement of cell or subcellular component;GO:0000278//mitotic cell cycle;GO:0006810//transport;GO:0045184//establishment of protein localization;GO:0000226//microtubule cytoskeleton organization;GO:0006928//movement of cell or subcellular component "gi|148664686|gb|EDK97102.1|/0/kinesin family member 20A, isoform CRA_b, partial [Mus musculus]" 76007 6876 2.6 2.393333333 -0.11949028 Down 0.172073038 Zmym2 "zinc finger, MYM-type 2" - GO:0016604//nuclear body;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0044390//ubiquitin-like protein conjugating enzyme binding "GO:0006351//transcription, DNA-templated" "gi|148704240|gb|EDL36187.1|/0/zinc finger, MYM-type 2, isoform CRA_b, partial [Mus musculus]" 232878 3076.24 2.4 2.613333333 0.122856748 Up 0.172073038 Zscan22 zinc finger and SCAN domain containing 22 K09230|1|0.0|735|mmu:232878|SCAN domain-containing zinc finger protein;K09228|2|0.0|652|rno:102553002|KRAB domain-containing zinc finger protein - - - gi|594190879|ref|NP_001277369.1|/0/zinc finger and SCAN domain-containing protein 22 isoform b [Mus musculus] 12394 7138 0.323333333 0.426666667 0.400087158 Up 0.171969611 Runx1 runt related transcription factor 1 K08367|1|1e-180|637|gga:396152|runt-related transcription factor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0031981//nuclear lumen;GO:0005578//proteinaceous extracellular matrix;GO:0031981//nuclear lumen;GO:0005578//proteinaceous extracellular matrix GO:0032550;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0008134//transcription factor binding;GO:0032550;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0008134//transcription factor binding;GO:0001067;GO:0046872//metal ion binding;GO:0008134//transcription factor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0032550;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0001067;GO:0046872//metal ion binding;GO:0008134//transcription factor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0032550;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity GO:0001525//angiogenesis;GO:0042127//regulation of cell proliferation;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0032370//positive regulation of lipid transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0001942//hair follicle development;GO:0043009//chordate embryonic development;GO:0007165//signal transduction;GO:0002244//hematopoietic progenitor cell differentiation;GO:0033993//response to lipid;GO:0044708//single-organism behavior;GO:0030182//neuron differentiation;GO:0001525//angiogenesis;GO:0042127//regulation of cell proliferation;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0032370//positive regulation of lipid transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0001942//hair follicle development;GO:0043009//chordate embryonic development;GO:0007165//signal transduction;GO:0002244//hematopoietic progenitor cell differentiation;GO:0033993//response to lipid;GO:0044708//single-organism behavior;GO:0030182//neuron differentiation;GO:0043009//chordate embryonic development;GO:0001942//hair follicle development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0007165//signal transduction;GO:0033993//response to lipid;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0042127//regulation of cell proliferation;GO:0044708//single-organism behavior;GO:0048666//neuron development;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0032370//positive regulation of lipid transport;GO:0043009//chordate embryonic development;GO:0001942//hair follicle development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0007165//signal transduction;GO:0033993//response to lipid;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0042127//regulation of cell proliferation;GO:0044708//single-organism behavior;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0032370//positive regulation of lipid transport gi|161169027|ref|NP_001104491.1|/0/runt-related transcription factor 1 isoform 1 [Mus musculus] 72225 2205 0.416666667 0.313333333 -0.411195433 Down 0.171969611 1700003M07Rik RIKEN cDNA 1700003M07 gene - - - - "gi|148698209|gb|EDL30156.1|/9.13686e-40/mCG1049168, isoform CRA_b, partial [Mus musculus]" 15985 1198 0.296666667 0.393333333 0.406909618 Up 0.171969611 Cd79b CD79B antigen K06507|1|2e-112|408|mmu:15985|CD79B antigen - - - - 17254 2598.61 37.5 38.70333333 0.045567229 Up 0.171819173 Slc3a2 "solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2" "K06519|1|0.0|932|mmu:17254|solute carrier family 3, member 2" GO:0044459;GO:0031224//intrinsic component of membrane;GO:0048770;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0048770 GO:0015171//amino acid transmembrane transporter activity;GO:0043167//ion binding;GO:0015171//amino acid transmembrane transporter activity;GO:0043167//ion binding GO:0015820//leucine transport;GO:0044238//primary metabolic process;GO:0015820//leucine transport;GO:0044238//primary metabolic process gi|238637277|ref|NP_001154885.1|/0/4F2 cell-surface antigen heavy chain isoform a [Mus musculus] 56709 1789 32.38333333 33.58666667 0.052637126 Up 0.171819173 Dnajb12 DnaJ heat shock protein family (Hsp40) member B12 K09518|1|2e-180|634|pale:102887512|DnaJ homolog subfamily B member 12 - - - - 210573 4853 0.056666667 0.123333333 1.121990524 Up 0.171809771 Tmem151b transmembrane protein 151B K06757|1|7e-150|535|chx:102181063|neurofascin GO:0031224//intrinsic component of membrane - - gi|85701444|ref|NP_001013771.1|/0/transmembrane protein 151B [Mus musculus] 15117 4262 0.123333333 0.056666667 -1.121990524 Down 0.171809771 Has2 hyaluronan synthase 2 K00752|1|0.0|1075|umr:103661603|hyaluronan synthase [EC:2.4.1.212] - - - - 57781 1891 0.056666667 0.123333333 1.121990524 Up 0.171809771 Cd200r1 CD200 receptor 1 K06531|1|1e-10|71.2|ola:101173334|poliovirus receptor-related protein 2;K06592|2|1e-09|67.8|ola:101160012|poliovirus receptor-related protein 3;K06081|3|2e-09|67.0|shr:100914634|poliovirus receptor-related protein 1 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0005488//binding - gi|10946634|ref|NP_067300.1|/2.41492e-171/cell surface glycoprotein CD200 receptor 1 precursor [Mus musculus] 72495 1717 0.06 0.13 1.115477217 Up 0.171809771 2610206C17Rik RIKEN cDNA 2610206C17 gene - - - - - 18577 4573.23 32.47666667 31.29 -0.053701907 Down 0.171762759 Pde4a "phosphodiesterase 4A, cAMP specific" K13293|1|0.0|1517|mmu:18577|cAMP-specific phosphodiesterase 4 [EC:3.1.4.53] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity" GO:0007606//sensory perception of chemical stimulus;GO:0046058//cAMP metabolic process;GO:0042493//response to drug "gi|111185525|gb|AAH27224.2|/0/Pde4a protein, partial [Mus musculus]" 241846 2560 31.13333333 32.31666667 0.053818348 Up 0.17164993 Lsm14b LSM family member 14B K18749|1|3e-161|571|mmu:241846|protein LSM14 - - - - 67480 3326 6.47 6.136666667 -0.076310491 Down 0.171621723 Cwc25 CWC25 spliceosome-associated protein K12182|1|1e-07|61.6|dpe:Dper_GL26577|hepatocyte growth factor-regulated tyrosine kinase substrate - - - - 110385 3305 6.166666667 5.836666667 -0.079346187 Down 0.171621723 Pde4c "phosphodiesterase 4C, cAMP specific" "K13293|1|0.0|1193|mmu:110385|cAMP-specific phosphodiesterase 4 [EC:3.1.4.53];K13755|5|0.0|897|myb:102263025|calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]" GO:0005929//cilium;GO:0005929//cilium "GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity" GO:0050796//regulation of insulin secretion;GO:0046058//cAMP metabolic process;GO:0050796//regulation of insulin secretion;GO:0046058//cAMP metabolic process "gi|148696916|gb|EDL28863.1|/0/phosphodiesterase 4C, cAMP specific, isoform CRA_a, partial [Mus musculus]" 57784 1727 5.77 6.103333333 0.081026066 Up 0.171621723 Bin3 bridging integrator 3 K20120|1|2e-139|498|mmu:57784|bridging integrator 3 GO:0043232 - GO:0000902//cell morphogenesis;GO:0033036 gi|10946638|ref|NP_067303.1|/1.40636e-138/bridging integrator 3 [Mus musculus] 268656 2601 5.81 6.143333333 0.080483502 Up 0.171621723 Sptlc1 "serine palmitoyltransferase, long chain base subunit 1" K00654|1|0.0|842|mmu:268656|serine palmitoyltransferase [EC:2.3.1.50] GO:0031224//intrinsic component of membrane;GO:0017059//serine C-palmitoyltransferase complex GO:0043168//anion binding;GO:0016454//C-palmitoyltransferase activity GO:0006684//sphingomyelin metabolic process;GO:0006667//sphinganine metabolic process;GO:0006670//sphingosine metabolic process "gi|148709175|gb|EDL41121.1|/0/serine palmitoyltransferase, long chain base subunit 1, partial [Mus musculus]" 71782 5257.97 5.463333333 5.793333333 0.084612228 Up 0.171621723 Ankle2 ankyrin repeat and LEM domain containing 2 K10591|1|8e-06|56.6|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0019903//protein phosphatase binding;GO:0019903//protein phosphatase binding GO:0006470//protein dephosphorylation;GO:0000087//mitotic M phase;GO:0016310//phosphorylation;GO:0006470//protein dephosphorylation;GO:0000087//mitotic M phase;GO:0016310//phosphorylation gi|40789239|ref|NP_082198.1|/0/ankyrin repeat and LEM domain-containing protein 2 isoform 2 [Mus musculus] 26465 2045 5.73 6.063333333 0.081575998 Up 0.171621723 Zfp146 zinc finger protein 146 K09228|1|7e-154|546|tup:102495972|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - "gi|743710024|ref|XP_010948465.1|/0/PREDICTED: LOW QUALITY PROTEIN: zinc finger protein OZF, partial [Camelus bactrianus]" 21973 5217 0.743333333 0.873333333 0.232523102 Up 0.171602919 Top2a topoisomerase (DNA) II alpha K03164|1|0.0|2713|mmu:21973|DNA topoisomerase II [EC:5.99.1.3] - - - gi|153945749|ref|NP_035753.2|/0/DNA topoisomerase 2-alpha [Mus musculus] 171207 3288 0.76 0.893333333 0.233199176 Up 0.171602919 Arhgap4 Rho GTPase activating protein 4 K20122|1|0.0|1633|mmu:171207|Rho GTPase-activating protein 4 GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0015630//microtubule cytoskeleton;GO:0005924//cell-substrate adherens junction;GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0015630//microtubule cytoskeleton;GO:0005924//cell-substrate adherens junction;GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0015630//microtubule cytoskeleton;GO:0005924//cell-substrate adherens junction - GO:0048731//system development;GO:0010761//fibroblast migration;GO:0030308//negative regulation of cell growth;GO:0048731//system development;GO:0010761//fibroblast migration;GO:0030308//negative regulation of cell growth;GO:0048731//system development;GO:0010761//fibroblast migration;GO:0030308//negative regulation of cell growth gi|244790127|ref|NP_619536.2|/0/rho GTPase-activating protein 4 isoform 1 [Mus musculus] 74136 4620.93 32.9 31.73 -0.052240063 Down 0.171574711 Sec14l1 SEC14-like lipid binding 1 - - - - gi|262073064|ref|NP_083053.2|/0/SEC14-like protein 1 isoform 1 [Mus musculus] 268566 3316 8.423333333 8.016666667 -0.07138877 Down 0.171546504 Gphn gephyrin K15376|1|0.0|1469|mmu:268566|gephyrin [EC:2.10.1.1 2.7.7.75] GO:0019898//extrinsic component of membrane;GO:0043232;GO:0097060//synaptic membrane GO:0043169//cation binding;GO:0032550;GO:0042802//identical protein binding;GO:0003824//catalytic activity GO:0018130;GO:0007528//neuromuscular junction development;GO:0051259//protein oligomerization;GO:0009108//coenzyme biosynthetic process;GO:0018130;GO:0008104//protein localization gi|269973917|ref|NP_666077.2|/0/gephyrin isoform 1 [Mus musculus] 103711 2048 13.87666667 14.44666667 0.058075595 Up 0.17145248 Pnpo pyridoxine 5'-phosphate oxidase K00275|1|2e-155|551|mmu:103711|pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5] GO:0044444//cytoplasmic part "GO:0032553//ribonucleotide binding;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor" GO:0009108//coenzyme biosynthetic process;GO:0008614//pyridoxine metabolic process gi|19527238|ref|NP_598782.1|/1.74259e-154/pyridoxine-5'-phosphate oxidase [Mus musculus] 19765 3813.23 14.13666667 14.70333333 0.056701277 Up 0.17145248 Ralbp1 ralA binding protein 1 K08773|1|0.0|947|mmu:19765|RalA-binding protein 1 GO:0016020//membrane;GO:0005622//intracellular;GO:0042995//cell projection;GO:0016020//membrane;GO:0005622//intracellular;GO:0042995//cell projection "GO:0017048//Rho GTPase binding;GO:0042623//ATPase activity, coupled;GO:0017048//Rho GTPase binding;GO:0042623//ATPase activity, coupled" GO:0000278//mitotic cell cycle;GO:0008285//negative regulation of cell proliferation;GO:0016192//vesicle-mediated transport;GO:0022402//cell cycle process;GO:0000278//mitotic cell cycle;GO:0008285//negative regulation of cell proliferation;GO:0016192//vesicle-mediated transport;GO:0022402//cell cycle process gi|74208441|dbj|BAE26405.1|/0/unnamed protein product [Mus musculus] 230737 2350 13.56666667 14.13666667 0.059375688 Up 0.17145248 Gnl2 guanine nucleotide binding protein-like 2 (nucleolar) K14537|1|0.0|1291|mmu:230737|nuclear GTP-binding protein - GO:0032550 - gi|240120093|ref|NP_663527.2|/0/nucleolar GTP-binding protein 2 [Mus musculus] 116871 1871.36 12.40333333 12.97 0.06445059 Up 0.17145248 Mta3 metastasis associated 3 K11660|1|0.0|993|mmu:116871|metastasis-associated protein MTA GO:0000118//histone deacetylase complex;GO:0000793//condensed chromosome;GO:0000118//histone deacetylase complex;GO:0000793//condensed chromosome;GO:0000118//histone deacetylase complex;GO:0000793//condensed chromosome;GO:0000118//histone deacetylase complex;GO:0000793//condensed chromosome GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0000086//G2/M transition of mitotic cell cycle;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation" "gi|148706611|gb|EDL38558.1|/0/metastasis associated 3, isoform CRA_e, partial [Mus musculus]" 21426 1779 0.06 0.126666667 1.078002512 Up 0.171443078 Tfec transcription factor EC K15591|1|3e-165|584|mmu:21426|transcription factor EC GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding "GO:0006351//transcription, DNA-templated;GO:0009408//response to heat" gi|568939519|ref|XP_006505098.1|/1.44549e-178/PREDICTED: transcription factor EC isoform X1 [Mus musculus] 75338 1399 0.073333333 0.146666667 1 Up 0.171443078 Ccdc83 coiled-coil domain containing 83 - - - - gi|308081925|ref|NP_899116.1|/0/coiled-coil domain-containing protein 83 isoform 1 [Mus musculus] 22066 3437 0.07 0.143333333 1.033947332 Up 0.171443078 Trpc4 "transient receptor potential cation channel, subfamily C, member 4" K04967|1|0.0|1624|rno:84494|transient receptor potential cation channel subfamily C member 4 GO:0005856//cytoskeleton;GO:0034703//cation channel complex;GO:0030054//cell junction;GO:0044459;GO:0030054//cell junction;GO:0005856//cytoskeleton;GO:0044459;GO:0034703//cation channel complex;GO:0005856//cytoskeleton;GO:0044459;GO:0034703//cation channel complex;GO:0005856//cytoskeleton;GO:0034703//cation channel complex;GO:0030054//cell junction;GO:0044459 GO:0050839//cell adhesion molecule binding;GO:0005262//calcium channel activity;GO:0043168//anion binding;GO:0043168//anion binding;GO:0005262//calcium channel activity;GO:0050839//cell adhesion molecule binding;GO:0043168//anion binding;GO:0005262//calcium channel activity;GO:0050839//cell adhesion molecule binding;GO:0050839//cell adhesion molecule binding;GO:0005262//calcium channel activity;GO:0043168//anion binding GO:0006935//chemotaxis;GO:0070588//calcium ion transmembrane transport;GO:0015812//gamma-aminobutyric acid transport;GO:0015812//gamma-aminobutyric acid transport;GO:0070588//calcium ion transmembrane transport;GO:0015812//gamma-aminobutyric acid transport;GO:0070588//calcium ion transmembrane transport;GO:0006935//chemotaxis;GO:0070588//calcium ion transmembrane transport;GO:0015812//gamma-aminobutyric acid transport "gi|148703306|gb|EDL35253.1|/0/transient receptor potential cation channel, subfamily C, member 4, isoform CRA_a, partial [Mus musculus]" 100041479 1412 0.14 0.066666667 -1.070389328 Down 0.171443078 Gm3363 predicted gene 3363 - - - - - 268935 2982 0.07 0.14 1 Up 0.171443078 Scube3 "signal peptide, CUB domain, EGF-like 3" K17307|1|1e-87|327|nvi:100115744|fibulin 1/2 GO:0044464 GO:0046872//metal ion binding GO:0051259//protein oligomerization "gi|52138546|ref|NP_001004366.1|/0/signal peptide, CUB and EGF-like domain-containing protein 3 precursor [Mus musculus]" 54426 2172 0.07 0.143333333 1.033947332 Up 0.171443078 Hgfac hepatocyte growth factor activator K09631|1|0.0|1287|mmu:54426|hepatocyte growth factor activator [EC:3.4.21.-] - - - - 378430 1439 0.136666667 0.066666667 -1.03562391 Down 0.171443078 Nanos2 nanos homolog 2 (Drosophila) K18760|1|2e-77|292|mmu:378430|protein nanos 2 GO:0035770//ribonucleoprotein granule;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0006412//translation;GO:0007126//meiotic nuclear division;GO:0006401//RNA catabolic process;GO:0019827//stem cell population maintenance;GO:0048232//male gamete generation gi|154090995|ref|NP_918953.2|/1.56756e-76/nanos homolog 2 [Mus musculus] 108978 2065 0.13 0.063333333 -1.037474705 Down 0.171443078 4930555G01Rik RIKEN cDNA 4930555G01 gene "K03844|1|5e-19|99.0|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - gi|283046813|ref|NP_780602.2|/5.03573e-101/uncharacterized protein LOC108978 [Mus musculus] 381033 4490 0.14 0.066666667 -1.070389328 Down 0.171443078 Gm1600 predicted gene 1600 - - - - gi|148664894|gb|EDK97310.1|/2.89739e-17/mCG1038318 [Mus musculus] 193813 2073.46 32.70666667 31.55 -0.051944728 Down 0.171414871 Mcfd2 multiple coagulation factor deficiency 2 K20364|1|2e-79|299|mmu:193813|multiple coagulation factor deficiency protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0043436;GO:0045184//establishment of protein localization;GO:0006810//transport;GO:0043436;GO:0045184//establishment of protein localization;GO:0006810//transport "gi|148706679|gb|EDL38626.1|/2.32826e-82/multiple coagulation factor deficiency 2, isoform CRA_b [Mus musculus]" 241950 2347 0.213333333 0.306666667 0.523561956 Up 0.171330249 Bbs12 Bardet-Biedl syndrome 12 (human) K19402|1|0.0|1410|mmu:241950|Bardet-Biedl syndrome 12 protein - - - gi|144922640|ref|NP_001008502.2|/0/Bardet-Biedl syndrome 12 protein homolog isoform 1 [Mus musculus] 96979 1969 32.72333333 31.57333333 -0.051613134 Down 0.171264433 Ptges2 prostaglandin E synthase 2 K05309|1|0.0|675|mmu:96979|microsomal prostaglandin-E synthase 2 [EC:5.3.99.3] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding;GO:0016860//intramolecular oxidoreductase activity;GO:0015036//disulfide oxidoreductase activity "GO:0006692;GO:0019725//cellular homeostasis;GO:0044765//single-organism transport;GO:0006351//transcription, DNA-templated" gi|260763900|ref|NP_598544.2|/0/prostaglandin E synthase 2 [Mus musculus] 224170 5153 0.313333333 0.22 -0.510194732 Down 0.171236226 Dzip3 "DAZ interacting protein 3, zinc finger" K10642|1|0.0|1504|cfa:478555|E3 ubiquitin-protein ligase DZIP3 [EC:2.3.2.27] GO:0044424 GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0043130//ubiquitin binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0019899//enzyme binding - gi|124249054|ref|NP_081617.1|/0/E3 ubiquitin-protein ligase DZIP3 isoform 2 [Mus musculus] 83671 3809.17 0.213333333 0.303333333 0.50779464 Up 0.171236226 Sytl2 synaptotagmin-like 2 K17598|1|0.0|1718|mmu:83671|synaptotagmin-like protein GO:0019898//extrinsic component of membrane;GO:0030133//transport vesicle;GO:0048770;GO:0019898//extrinsic component of membrane;GO:0030133//transport vesicle;GO:0048770;GO:0019898//extrinsic component of membrane;GO:0030133//transport vesicle;GO:0048770;GO:0019898//extrinsic component of membrane;GO:0030133//transport vesicle;GO:0048770;GO:0019898//extrinsic component of membrane;GO:0030133//transport vesicle;GO:0048770;GO:0019898//extrinsic component of membrane;GO:0030133//transport vesicle;GO:0048770;GO:0019898//extrinsic component of membrane;GO:0030133//transport vesicle;GO:0048770;GO:0019898//extrinsic component of membrane;GO:0030133//transport vesicle;GO:0048770;GO:0019898//extrinsic component of membrane;GO:0030133//transport vesicle;GO:0048770 GO:0043168//anion binding;GO:0017016//Ras GTPase binding;GO:0043168//anion binding;GO:0017016//Ras GTPase binding;GO:0043168//anion binding;GO:0017016//Ras GTPase binding;GO:0043168//anion binding;GO:0017016//Ras GTPase binding;GO:0043168//anion binding;GO:0017016//Ras GTPase binding;GO:0043168//anion binding;GO:0017016//Ras GTPase binding;GO:0043168//anion binding;GO:0017016//Ras GTPase binding;GO:0043168//anion binding;GO:0017016//Ras GTPase binding;GO:0043168//anion binding;GO:0017016//Ras GTPase binding GO:0051047//positive regulation of secretion;GO:0006887//exocytosis;GO:0015031//protein transport;GO:0010921//regulation of phosphatase activity;GO:0051047//positive regulation of secretion;GO:0006887//exocytosis;GO:0015031//protein transport;GO:0010921//regulation of phosphatase activity;GO:0051047//positive regulation of secretion;GO:0006887//exocytosis;GO:0015031//protein transport;GO:0010921//regulation of phosphatase activity;GO:0051047//positive regulation of secretion;GO:0006887//exocytosis;GO:0015031//protein transport;GO:0010921//regulation of phosphatase activity;GO:0051047//positive regulation of secretion;GO:0006887//exocytosis;GO:0015031//protein transport;GO:0010921//regulation of phosphatase activity;GO:0051047//positive regulation of secretion;GO:0006887//exocytosis;GO:0015031//protein transport;GO:0010921//regulation of phosphatase activity;GO:0051047//positive regulation of secretion;GO:0006887//exocytosis;GO:0015031//protein transport;GO:0010921//regulation of phosphatase activity;GO:0051047//positive regulation of secretion;GO:0006887//exocytosis;GO:0015031//protein transport;GO:0010921//regulation of phosphatase activity;GO:0051047//positive regulation of secretion;GO:0006887//exocytosis;GO:0015031//protein transport;GO:0010921//regulation of phosphatase activity gi|13647015|dbj|BAB41083.1|/0/synaptotagmin-like protein 2-b [Mus musculus] 219105 5357.2 4.353333333 4.076666667 -0.094730493 Down 0.171217421 Zmym5 "zinc finger, MYM-type 5" K02981|1|2e-50|99.0|nle:100581646|small subunit ribosomal protein S2e GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - gi|568987346|ref|XP_006518915.1|/0/PREDICTED: zinc finger MYM-type protein 5 isoform X2 [Mus musculus] 226421 4455.95 1.586666667 1.756666667 0.146841388 Up 0.171085787 Rab7b "RAB7B, member RAS oncogene family" K07898|1|6e-110|402|mmu:226421|Ras-related protein Rab-7B - - - - 83961 1952 1.713333333 1.546666667 -0.147643554 Down 0.171085787 Nrg4 neuregulin 4 K05458|1|2e-34|150|rno:690919|neuregulin 4 GO:0016020//membrane - - "gi|300798035|ref|NP_001178038.1|/1.43571e-33/pro-neuregulin-4, membrane-bound isoform [Rattus norvegicus]" 67921 1363 30.6 31.74 0.052770475 Up 0.171085787 Ube2f ubiquitin-conjugating enzyme E2F (putative) K10687|1|5e-94|347|mmu:67921|ubiquitin-conjugating enzyme E2 F [EC:2.3.2.23] - GO:0019787//ubiquitin-like protein transferase activity;GO:0032550 GO:0032446//protein modification by small protein conjugation "gi|148708111|gb|EDL40058.1|/7.69797e-94/mCG12870, isoform CRA_c, partial [Mus musculus]" 70729 2704.17 1.786666667 1.613333333 -0.147225953 Down 0.171085787 Nos1ap nitric oxide synthase 1 (neuronal) adaptor protein K16513|1|1e-117|426|mmu:70729|carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein GO:0044424;GO:0044424 GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding GO:0006915//apoptotic process;GO:0001505//regulation of neurotransmitter levels;GO:0032768;GO:0006809//nitric oxide biosynthetic process;GO:0006915//apoptotic process;GO:0001505//regulation of neurotransmitter levels;GO:0032768;GO:0006809//nitric oxide biosynthetic process gi|158508485|ref|NP_001103455.1|/0/carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform 1 [Mus musculus] 72404 4151.57 1.48 1.646666667 0.153951365 Up 0.171085787 Wdr44 WD repeat domain 44 K20241|1|0.0|1636|mmu:72404|WD repeat-containing protein 44 GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0017016//Ras GTPase binding;GO:0017016//Ras GTPase binding GO:0016477//cell migration;GO:0016477//cell migration gi|124249073|ref|NP_780389.2|/0/WD repeat-containing protein 44 [Mus musculus] 60527 3269 30.99 32.13 0.052118226 Up 0.171085787 Fads3 fatty acid desaturase 3 K10225|1|0.0|872|mmu:60527|fatty acid desaturase 3 (Delta-13 desaturase) [EC:1.14.19.-] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0046906//tetrapyrrole binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" GO:0051234//establishment of localization;GO:0006631//fatty acid metabolic process;GO:0006091//generation of precursor metabolites and energy gi|74181920|dbj|BAE32659.1|/0/unnamed protein product [Mus musculus] 217216 2543 0.113333333 0.193333333 0.770518154 Up 0.171066983 BC030867 cDNA sequence BC030867 - - - - gi|110347505|ref|NP_705772.3|/0/uncharacterized protein C17orf53 homolog [Mus musculus] 74330 4229 13.73333333 13.17333333 -0.06006139 Down 0.171010568 Dnajc14 DnaJ heat shock protein family (Hsp40) member C14 K09534|1|0.0|1279|mmu:74330|DnaJ homolog subfamily C member 14 - - - - 72265 2943 14.79 14.23 -0.055686391 Down 0.171010568 Tram1 translocating chain-associating membrane protein 1 K14010|1|0.0|702|mmu:72265|translocating chain-associated membrane protein 1 GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0045184//establishment of protein localization gi|30794386|ref|NP_082449.1|/0/translocating chain-associated membrane protein 1 [Mus musculus] 56440 2079 14.06666667 14.62666667 0.056320527 Up 0.171010568 Snx1 sorting nexin 1 K17917|1|0.0|932|mmu:56440|sorting nexin-1/2 GO:0005769//early endosome;GO:0031090//organelle membrane GO:0022892//substrate-specific transporter activity;GO:0005543//phospholipid binding GO:0009896;GO:0044765//single-organism transport;GO:0016482//cytosolic transport;GO:0015031//protein transport gi|71043944|ref|NP_062701.2|/0/sorting nexin-1 [Mus musculus] 13171 3292 14.80333333 14.24333333 -0.055635254 Down 0.171010568 Dbt dihydrolipoamide branched chain transacylase E2 K09699|1|0.0|869|mmu:13171|2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168] GO:0005856//cytoskeleton;GO:0005759//mitochondrial matrix "GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0005488//binding" GO:0035337 "gi|170172520|ref|NP_034152.2|/0/lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial [Mus musculus]" 100043272 3053 13.19 13.75333333 0.060336756 Up 0.171010568 Inafm2 InaF motif containing 2 - - - - gi|927096609|ref|XP_013841036.1|/1.34376e-31/PREDICTED: putative transmembrane protein INAFM2 [Sus scrofa] 11501 3114.07 0.316666667 0.413333333 0.384340702 Up 0.170972959 Adam8 a disintegrin and metallopeptidase domain 8 K06540|1|0.0|1464|mmu:11501|disintegrin and metalloproteinase domain-containing protein 8 [EC:3.4.24.-] GO:0043234//protein complex;GO:0015629//actin cytoskeleton;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0005767//secondary lysosome;GO:0043234//protein complex;GO:0015629//actin cytoskeleton;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0005767//secondary lysosome GO:0005102//receptor binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0002761//regulation of myeloid leukocyte differentiation;GO:0032846;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0033077//T cell differentiation in thymus;GO:0006509//membrane protein ectodomain proteolysis;GO:0001666//response to hypoxia;GO:0030595//leukocyte chemotaxis;GO:0043542//endothelial cell migration;GO:0001819//positive regulation of cytokine production;GO:0002526//acute inflammatory response;GO:0000768//syncytium formation by plasma membrane fusion;GO:0031589//cell-substrate adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0072681;GO:0000187//activation of MAPK activity;GO:0002693//positive regulation of cellular extravasation;GO:0043066//negative regulation of apoptotic process;GO:0070234//positive regulation of T cell apoptotic process;GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0002761//regulation of myeloid leukocyte differentiation;GO:0032846;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0033077//T cell differentiation in thymus;GO:0006509//membrane protein ectodomain proteolysis;GO:0001666//response to hypoxia;GO:0030595//leukocyte chemotaxis;GO:0043542//endothelial cell migration;GO:0001819//positive regulation of cytokine production;GO:0002526//acute inflammatory response;GO:0000768//syncytium formation by plasma membrane fusion;GO:0031589//cell-substrate adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0072681;GO:0000187//activation of MAPK activity;GO:0002693//positive regulation of cellular extravasation;GO:0043066//negative regulation of apoptotic process;GO:0070234//positive regulation of T cell apoptotic process "gi|148685931|gb|EDL17878.1|/0/a disintegrin and metallopeptidase domain 8, isoform CRA_b, partial [Mus musculus]" 81897 3471 0.436666667 0.336666667 -0.375211519 Down 0.170972959 Tlr9 toll-like receptor 9 K10161|1|0.0|1941|mmu:81897|toll-like receptor 9 GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0045335//phagocytic vesicle;GO:0044459 GO:0005126//cytokine receptor binding;GO:0003723//RNA binding;GO:0043565//sequence-specific DNA binding GO:0006954//inflammatory response;GO:0042095//interferon-gamma biosynthetic process;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0006914//autophagy;GO:0032481//positive regulation of type I interferon production;GO:0008406//gonad development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0043406//positive regulation of MAP kinase activity;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0052166;GO:0002252;GO:0001774//microglial cell activation;GO:0010038//response to metal ion;GO:0010669//epithelial structure maintenance;GO:0006366//transcription from RNA polymerase II promoter;GO:0002224//toll-like receptor signaling pathway;GO:0001818//negative regulation of cytokine production;GO:0032496//response to lipopolysaccharide;GO:0042345//regulation of NF-kappaB import into nucleus gi|157057166|ref|NP_112455.2|/0/toll-like receptor 9 precursor [Mus musculus] 209351 796 0.45 0.346666667 -0.376375879 Down 0.170972959 Wfdc6a WAP four-disulfide core domain 6A K12864|1|1e-13|79.0|clv:102090334|beta-catenin-like protein 1;K03909|2|3e-12|74.7|crg:105330341|tissue factor pathway inhibitor;K08117|5|1e-11|72.8|dre:796801|amyloid-like protein 2 - GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity GO:0051346//negative regulation of hydrolase activity;GO:0051346//negative regulation of hydrolase activity "gi|148674455|gb|EDL06402.1|/9.62675e-83/mCG141701, partial [Mus musculus]" 98363 1805 1.84 2.023333333 0.137028249 Up 0.170972959 Efhd1 EF hand domain containing 1 K01311|1|8e-28|127|apla:101795575|chymotrypsin C [EC:3.4.21.2] GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding GO:0030030//cell projection organization "gi|148708228|gb|EDL40175.1|/2.32326e-107/EF hand domain containing 1, isoform CRA_c, partial [Mus musculus]" 22785 5409.7 1.836666667 2.02 0.137265475 Up 0.170972959 Slc30a4 "solute carrier family 30 (zinc transporter), member 4" "K14691|1|9e-178|627|mmu:22785|solute carrier family 30 (zinc transporter), member 4" GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0031090//organelle membrane GO:0015075//ion transmembrane transporter activity GO:0010038//response to metal ion;GO:0006829//zinc II ion transport;GO:0033273//response to vitamin;GO:0032119//sequestering of zinc ion;GO:0007589//body fluid secretion gi|52630421|ref|NP_035904.2|/0/zinc transporter 4 isoform a [Mus musculus] 77414 963 0.11 0.186666667 0.762960803 Up 0.17089774 C030013G03Rik RIKEN cDNA C030013G03 gene - - - - gi|148670113|gb|EDL02060.1|/1.51438e-28/mCG147021 [Mus musculus] 231946 2013 0.12 0.203333333 0.760812336 Up 0.17089774 Fam221a "family with sequence similarity 221, member A" - - - - "gi|148666194|gb|EDK98610.1|/2.0028e-171/RIKEN cDNA D330028D13, isoform CRA_c, partial [Mus musculus]" 14600 2856.36 32.99 31.87333333 -0.049678873 Down 0.170850728 Ghr growth hormone receptor K05080|1|0.0|1327|mmu:14600|growth hormone receptor GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0044421;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0044421;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0016021//integral component of membrane;GO:0043235//receptor complex;GO:0044421 GO:0004896//cytokine receptor activity;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0019902//phosphatase binding;GO:0042277//peptide binding;GO:0019900//kinase binding;GO:0004896//cytokine receptor activity;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0019902//phosphatase binding;GO:0042277//peptide binding;GO:0019900//kinase binding;GO:0004896//cytokine receptor activity;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0019902//phosphatase binding;GO:0042277//peptide binding;GO:0019900//kinase binding GO:0043648//dicarboxylic acid metabolic process;GO:0006575//cellular modified amino acid metabolic process;GO:0032868//response to insulin;GO:0060548//negative regulation of cell death;GO:0072338;GO:0006898//receptor-mediated endocytosis;GO:0072350//tricarboxylic acid metabolic process;GO:0042976//activation of Janus kinase activity;GO:0014072//response to isoquinoline alkaloid;GO:0043627//response to estrogen;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0034097//response to cytokine;GO:0006790//sulfur compound metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0030154//cell differentiation;GO:0009081//branched-chain amino acid metabolic process;GO:0031960//response to corticosteroid;GO:0044767//single-organism developmental process;GO:0035264//multicellular organism growth;GO:0031667//response to nutrient levels;GO:0043648//dicarboxylic acid metabolic process;GO:0006575//cellular modified amino acid metabolic process;GO:0032868//response to insulin;GO:0060548//negative regulation of cell death;GO:0072338;GO:0006898//receptor-mediated endocytosis;GO:0072350//tricarboxylic acid metabolic process;GO:0042976//activation of Janus kinase activity;GO:0014072//response to isoquinoline alkaloid;GO:0043627//response to estrogen;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0034097//response to cytokine;GO:0006790//sulfur compound metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0030154//cell differentiation;GO:0009081//branched-chain amino acid metabolic process;GO:0031960//response to corticosteroid;GO:0044767//single-organism developmental process;GO:0035264//multicellular organism growth;GO:0031667//response to nutrient levels;GO:0043648//dicarboxylic acid metabolic process;GO:0006575//cellular modified amino acid metabolic process;GO:0032868//response to insulin;GO:0060548//negative regulation of cell death;GO:0072338;GO:0006898//receptor-mediated endocytosis;GO:0072350//tricarboxylic acid metabolic process;GO:0042976//activation of Janus kinase activity;GO:0014072//response to isoquinoline alkaloid;GO:0043627//response to estrogen;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0034097//response to cytokine;GO:0006790//sulfur compound metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0030154//cell differentiation;GO:0009081//branched-chain amino acid metabolic process;GO:0031960//response to corticosteroid;GO:0044767//single-organism developmental process;GO:0035264//multicellular organism growth;GO:0031667//response to nutrient levels gi|114520600|ref|NP_034414.2|/0/growth hormone receptor isoform 1 precursor [Mus musculus] 209318 1866.14 30.72333333 31.84333333 0.051656614 Up 0.170850728 Gps1 G protein pathway suppressor 1 K12175|1|0.0|915|rno:117039|COP9 signalosome complex subunit 1 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0000338//protein deneddylation;GO:0000338//protein deneddylation gi|295424137|ref|NP_663345.2|/0/COP9 signalosome complex subunit 1 isoform 1 [Mus musculus] 17281 7705.08 33.71333333 34.83333333 0.047149259 Up 0.170850728 Fyco1 FYVE and coiled-coil domain containing 1 K12478|1|2e-28|132|mze:101467934|early endosome antigen 1 GO:0005768//endosome;GO:0000323//lytic vacuole;GO:0031982//vesicle;GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0000323//lytic vacuole;GO:0031982//vesicle;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0043169//cation binding GO:0047496//vesicle transport along microtubule;GO:0047496//vesicle transport along microtubule gi|485050407|ref|NP_683727.3|/0/FYVE and coiled-coil domain-containing protein 1 [Mus musculus] 22248 1265.58 3.71 3.466666667 -0.097870064 Down 0.170784911 Unc119 unc-119 lipid binding chaperone "K05291|1|2e-91|338|bacu:102997806|phosphatidylinositol glycan, class S" GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part;GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0050953//sensory perception of light stimulus;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0015031//protein transport;GO:0050953//sensory perception of light stimulus;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0015031//protein transport;GO:0050953//sensory perception of light stimulus;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0015031//protein transport;GO:0050953//sensory perception of light stimulus;GO:0015031//protein transport;GO:0044699;GO:0015031//protein transport gi|928589405|ref|NP_001300916.1|/1.65529e-98/protein unc-119 homolog A isoform 4 [Mus musculus] 69573 985 3.243333333 3.486666667 0.104371141 Up 0.170784911 Hilpda hypoxia inducible lipid droplet associated - "GO:0044421;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0016020//membrane;GO:0044421;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0016020//membrane" GO:0005515//protein binding;GO:0005515//protein binding GO:0008283//cell proliferation;GO:0010883//regulation of lipid storage;GO:0007267//cell-cell signaling;GO:0008283//cell proliferation;GO:0010883//regulation of lipid storage;GO:0007267//cell-cell signaling gi|299758486|ref|NP_001177390.1|/6.87166e-29/hypoxia-inducible lipid droplet-associated protein isoform 1 [Mus musculus] 74159 3644.4 3.54 3.296666667 -0.10274134 Down 0.170784911 Acbd5 acyl-Coenzyme A binding domain containing 5 "K13239|1|1e-14|85.5|pon:100459134|peroxisomal 3,2-trans-enoyl-CoA isomerase [EC:5.3.3.8]" GO:0044439;GO:0031224//intrinsic component of membrane;GO:0044439;GO:0031224//intrinsic component of membrane;GO:0044439;GO:0031224//intrinsic component of membrane;GO:0044439;GO:0031224//intrinsic component of membrane GO:0043168//anion binding;GO:0043168//anion binding;GO:0043168//anion binding;GO:0043168//anion binding GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization "gi|31566352|gb|AAH53518.1|/0/Acbd5 protein, partial [Mus musculus]" 19106 4343 3.54 3.303333333 -0.099826804 Down 0.170784911 Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 K16195|1|0.0|908|mmu:19106|eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0008135//translation factor activity, RNA binding;GO:0019888//protein phosphatase regulator activity" GO:0006984//ER-nucleus signaling pathway;GO:0009605//response to external stimulus;GO:0006412//translation;GO:0019049//evasion or tolerance of host defenses by virus;GO:0008285//negative regulation of cell proliferation;GO:0002252;GO:0006468//protein phosphorylation;GO:0043331//response to dsRNA;GO:0002237//response to molecule of bacterial origin "gi|568999442|ref|XP_006523926.1|/0/PREDICTED: interferon-induced, double-stranded RNA-activated protein kinase isoform X1 [Mus musculus]" 108934 4499 8.473333333 8.873333333 0.066546541 Up 0.170766106 Smim13 small integral membrane protein 13 - GO:0031224//intrinsic component of membrane - - "gi|148709026|gb|EDL40972.1|/1.25088e-44/mCG10996, partial [Mus musculus]" 68597 2934.7 7.693333333 8.093333333 0.073125198 Up 0.170766106 Ccdc167 coiled-coil domain containing 167 - - - - "gi|148690682|gb|EDL22629.1|/7.91752e-54/mCG21143, isoform CRA_a [Mus musculus]" 26754 1731 34.76333333 35.87333333 0.045345382 Up 0.170747302 Cops5 COP9 signalosome subunit 5 K09613|1|2e-166|528|ngi:103751377|COP9 signalosome complex subunit 5 [EC:3.4.-.-] - - - - 228564 4218 29.84 28.73 -0.054689543 Down 0.170747302 Frmd5 FERM domain containing 5 K06107|1|3e-60|236|fab:101821182|erythrocyte membrane protein band 4.1 GO:0044425;GO:0043232 GO:0005515//protein binding - gi|51036627|ref|NP_766261.2|/0/FERM domain-containing protein 5 [Mus musculus] 57890 2828.75 0.223333333 0.316666667 0.503766418 Up 0.170625071 Il17re interleukin 17 receptor E K05168|1|0.0|1118|mmu:57890|interleukin 17 receptor E GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane - GO:0006952//defense response;GO:0006952//defense response;GO:0006952//defense response gi|31559935|ref|NP_665825.2|/0/interleukin-17 receptor E isoform 1 precursor [Mus musculus] 74570 8244.68 2.24 2.05 -0.127874823 Down 0.170606266 Zkscan1 zinc finger with KRAB and SCAN domains 1 K09229|1|0.0|1021|mmu:74570|KRAB and SCAN domains-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0044764;GO:0006351//transcription, DNA-templated;GO:0044764;GO:0006351//transcription, DNA-templated" gi|68510029|ref|NP_084145.1|/0/zinc finger protein with KRAB and SCAN domains 1 isoform 2 [Mus musculus] 83796 2598.96 13.36 13.91 0.058202412 Up 0.170606266 Smarcd2 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2" K11650|1|0.0|866|cge:100770817|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D GO:0090544//BAF-type complex - "GO:0016568//chromatin modification;GO:0006351//transcription, DNA-templated;GO:0034728//nucleosome organization" gi|194328771|ref|NP_114084.2|/0/SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 isoform 2 [Mus musculus] 230866 6237 12.96333333 13.51 0.059590941 Up 0.170606266 Emc1 ER membrane protein complex subunit 1 "K03847|1|1e-06|59.3|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane - - gi|120537280|gb|AAI29805.1|/0/C230096C10Rik protein [Mus musculus] 67065 2036.67 13.42 12.87 -0.060372618 Down 0.170606266 Polr3d polymerase (RNA) III (DNA directed) polypeptide D K03026|1|4e-173|610|mmu:67065|DNA-directed RNA polymerase III subunit RPC4 GO:0044451;GO:0044451 GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity;GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity GO:0006383//transcription from RNA polymerase III promoter;GO:0031349//positive regulation of defense response;GO:0032481//positive regulation of type I interferon production;GO:0002252;GO:0006383//transcription from RNA polymerase III promoter;GO:0031349//positive regulation of defense response;GO:0032481//positive regulation of type I interferon production;GO:0002252 "gi|148703955|gb|EDL35902.1|/1.43748e-177/polymerase (RNA) III (DNA directed) polypeptide D, isoform CRA_b, partial [Mus musculus]" 99899 2916 2.03 2.223333333 0.131244533 Up 0.170606266 Ifi44 interferon-induced protein 44 - - - - - 57778 3780.06 12.76333333 12.21 -0.063941959 Down 0.170606266 Fmnl1 formin-like 1 K04512|1|8e-50|202|apla:101796496|dishevelled associated activator of morphogenesis GO:0030139//endocytic vesicle;GO:0016020//membrane;GO:0030139//endocytic vesicle;GO:0016020//membrane GO:0003779//actin binding;GO:0017048//Rho GTPase binding;GO:0003779//actin binding;GO:0017048//Rho GTPase binding GO:0016477//cell migration;GO:0022604//regulation of cell morphogenesis;GO:0030036//actin cytoskeleton organization;GO:0016477//cell migration;GO:0022604//regulation of cell morphogenesis;GO:0030036//actin cytoskeleton organization gi|118136288|ref|NP_001071166.1|/0/formin-like protein 1 isoform 2 [Mus musculus] 70575 2036 2.04 2.233333333 0.130629443 Up 0.170606266 Gfod2 glucose-fructose oxidoreductase domain containing 2 - GO:0031012//extracellular matrix GO:0003824//catalytic activity GO:0044710;GO:0043062//extracellular structure organization gi|21312610|ref|NP_081745.1|/0/glucose-fructose oxidoreductase domain-containing protein 2 precursor [Mus musculus] 223864 3825 13.86666667 13.31666667 -0.058388025 Down 0.170606266 Rapgef3 Rap guanine nucleotide exchange factor (GEF) 3 K08014|1|0.0|1759|mmu:223864|Rap guanine nucleotide exchange factor 3 - - - gi|295317407|ref|NP_001171282.1|/0/rap guanine nucleotide exchange factor 3 isoform 3 [Mus musculus] 624549 1902 2.276666667 2.083333333 -0.128029389 Down 0.170606266 Gm29683 "predicted gene, 29683" K11290|1|6e-08|62.0|rno:317165|template-activating factor I - - - - 244672 3953 1.95 2.136666667 0.131887732 Up 0.170606266 Cwf19l2 "CWF19-like 2, cell cycle control (S. pombe)" K04467|1|1e-12|78.6|fpg:101914413|inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10] - - - gi|30842792|ref|NP_081821.1|/0/CWF19-like protein 2 [Mus musculus] 68082 1463 2.106666667 1.92 -0.133855747 Down 0.170606266 Dusp19 dual specificity phosphatase 19 K14165|1|7e-123|443|mmu:68082|atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] GO:0044424 GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0019901//protein kinase binding;GO:0019887//protein kinase regulator activity;GO:0032947//protein complex scaffold GO:0043407//negative regulation of MAP kinase activity;GO:0007254//JNK cascade;GO:0043406//positive regulation of MAP kinase activity gi|13277360|ref|NP_077758.1|/5.63036e-122/dual specificity protein phosphatase 19 [Mus musculus] 69260 2813 1.27 1.123333333 -0.177042406 Down 0.170596863 Ing2 "inhibitor of growth family, member 2" K19198|1|3e-107|392|mmu:69260|inhibitor of growth protein 2 GO:0005667//transcription factor complex;GO:0070822//Sin3-type complex GO:0042393//histone binding;GO:0005543//phospholipid binding;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding "GO:0006351//transcription, DNA-templated;GO:0007127//meiosis I;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0006915//apoptotic process;GO:0048870//cell motility;GO:0007281//germ cell development;GO:0006325//chromatin organization" gi|31542996|ref|NP_075992.2|/2.58112e-106/inhibitor of growth protein 2 [Mus musculus] 217935 3725 1.1 1.25 0.184424571 Up 0.170596863 Wdr60 WD repeat domain 60 "K10415|1|4e-12|77.0|cmk:103189508|dynein intermediate chain, cytosolic" GO:0043231//intracellular membrane-bounded organelle - - gi|113199781|ref|NP_666151.3|/0/WD repeat-containing protein 60 [Mus musculus] 213464 3632 5.313333333 5.633333333 0.084371617 Up 0.170408816 Rbbp5 retinoblastoma binding protein 5 K14961|1|0.0|1033|mmu:213464|COMPASS component SWD1 GO:0044665//MLL1/2 complex GO:0042393//histone binding;GO:0000975//regulatory region DNA binding;GO:0018024//histone-lysine N-methyltransferase activity "GO:0034968//histone lysine methylation;GO:0048545//response to steroid hormone;GO:0033554//cellular response to stress;GO:0006351//transcription, DNA-templated" gi|164450487|ref|NP_766105.2|/0/retinoblastoma-binding protein 5 [Mus musculus] 66381 1393 6.16 5.843333333 -0.076138761 Down 0.170408816 Rnf113a2 ring finger protein 113A2 K13127|1|0.0|673|mmu:66381|RING finger protein 113A - GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding - "gi|148670854|gb|EDL02801.1|/0/ring finger protein 113A2, partial [Mus musculus]" 110175 1362 5.986666667 6.31 0.075887061 Up 0.170408816 Ggct gamma-glutamyl cyclotransferase K00682|1|2e-106|388|mmu:110175|gamma-glutamylcyclotransferase [EC:2.3.2.4] GO:0044444//cytoplasmic part "GO:0042802//identical protein binding;GO:0016755//transferase activity, transferring amino-acyl groups" GO:0006749//glutathione metabolic process gi|21311849|ref|NP_080913.1|/1.94673e-105/gamma-glutamylcyclotransferase [Mus musculus] 67302 6151 5.97 5.653333333 -0.078629167 Down 0.170408816 Zc3h13 zinc finger CCCH type containing 13 - - - - gi|61742810|ref|NP_080359.2|/0/zinc finger CCCH domain-containing protein 13 [Mus musculus] 330050 3082 5.823333333 6.143333333 0.077176463 Up 0.170408816 Fam185a "family with sequence similarity 185, member A" - - - - gi|61098169|ref|NP_808537.2|/0/protein FAM185A [Mus musculus] 320871 2935 0.43 0.333333333 -0.367371066 Down 0.170408816 B230206H07Rik RIKEN cDNA B230206H07 gene K17277|1|1e-57|228|mmu:98845|epidermal growth factor receptor kinase substrate 8 - GO:0003779//actin binding GO:0007265//Ras protein signal transduction "gi|148686107|gb|EDL18054.1|/8.85926e-57/EPS8-like 2, isoform CRA_c [Mus musculus]" 83429 3010 5.666666667 5.983333333 0.078449098 Up 0.170408816 Ctns "cystinosis, nephropathic" K12386|1|0.0|693|mmu:83429|cystinosin GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0005768//endosome GO:0000099 GO:0000101//sulfur amino acid transport;GO:0009150//purine ribonucleotide metabolic process;GO:0007613//memory;GO:0007417//central nervous system development;GO:0007632//visual behavior;GO:0006790//sulfur compound metabolic process;GO:0044767//single-organism developmental process;GO:0019752//carboxylic acid metabolic process;GO:0008344//adult locomotory behavior gi|755540062|ref|XP_011247625.1|/0/PREDICTED: cystinosin isoform X1 [Mus musculus] 73942 1398 1.126666667 0.983333333 -0.196308292 Down 0.170390011 Fam151b "family with sequence similarity 151, member B" "K04679|1|1e-35|153|aam:106496341|MAD, mothers against decapentaplegic interacting protein" - - - gi|148668637|gb|EDL00956.1|/2.10887e-171/mCG131442 [Mus musculus] 68177 2077 0.953333333 1.093333333 0.197680668 Up 0.170390011 Ebpl emopamil binding protein-like K01824|1|1e-20|103|pbi:103051122|cholestenol Delta-isomerase [EC:5.3.3.5] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle "GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds" GO:0006066//alcohol metabolic process gi|225579144|ref|NP_080874.2|/4.01966e-98/emopamil-binding protein-like [Mus musculus] 66790 1310 0.956666667 1.1 0.201415288 Up 0.170390011 Grtp1 GH regulated TBC protein 1 K19953|1|0.0|664|mmu:66790|TBC1 domain family member 6 GO:0044464 - - gi|85861226|ref|NP_080044.2|/0/growth hormone-regulated TBC protein 1 [Mus musculus] 235072 2532.67 31.13666667 30.07 -0.050289637 Down 0.170305389 7-Sep septin 7 K16944|1|0.0|764|mmu:235072|septin 7 "GO:0031981//nuclear lumen;GO:0032156//septin cytoskeleton;GO:0032432//actin filament bundle;GO:0015630//microtubule cytoskeleton;GO:0032155;GO:0000776//kinetochore;GO:0005930//axoneme;GO:0033267;GO:0044459;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0031981//nuclear lumen;GO:0032155;GO:0044459;GO:0033267;GO:0000775//chromosome, centromeric region;GO:0032156//septin cytoskeleton;GO:0044444//cytoplasmic part;GO:0032432//actin filament bundle;GO:0005930//axoneme" GO:0032550;GO:0032550 GO:0008360//regulation of cell shape;GO:0051259//protein oligomerization;GO:0048858//cell projection morphogenesis;GO:0000087//mitotic M phase;GO:0048858//cell projection morphogenesis;GO:0008360//regulation of cell shape;GO:0051259//protein oligomerization;GO:0000087//mitotic M phase gi|880929535|ref|XP_005078560.2|/0/PREDICTED: septin-7 isoform X1 [Mesocricetus auratus] 380855 2046 0.793333333 0.926666667 0.224123309 Up 0.170248975 Rsl1 regulator of sex limited protein 1 K09228|1|0.0|989|mmu:380855|KRAB domain-containing zinc finger protein - - - - 94187 4349 0.96 0.826666667 -0.215728691 Down 0.170248975 Zfp423 zinc finger protein 423 K09228|1|2e-87|327|bfo:BRAFLDRAFT_71028|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0046983//protein dimerization activity GO:0048869//cellular developmental process;GO:0048731//system development;GO:0030509//BMP signaling pathway gi|568957910|ref|XP_006531597.1|/0/PREDICTED: zinc finger protein 423 isoform X2 [Mus musculus] 103142 2698 0.816666667 0.95 0.21818017 Up 0.170248975 Rdh9 retinol dehydrogenase 9 K11154|1|0.0|639|mmu:103142|retinol dehydrogenase 16 [EC:1.1.1.-] GO:0044432;GO:0016021//integral component of membrane "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0036094//small molecule binding" GO:0002138//retinoic acid biosynthetic process gi|23680945|ref|NP_694773.1|/1.15207e-180/retinol dehydrogenase 9 precursor [Mus musculus] 66988 2267 30.59 29.53333333 -0.050715909 Down 0.170183158 Lap3 leucine aminopeptidase 3 K11142|1|0.0|995|mmu:66988|cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5] GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0008237//metallopeptidase activity GO:0019538//protein metabolic process gi|255069715|ref|NP_077754.3|/0/cytosol aminopeptidase [Mus musculus] 67976 2393 28.4 27.34 -0.054877687 Down 0.170183158 Trabd TraB domain containing - - - - gi|12857145|dbj|BAB30908.1|/0/unnamed protein product [Mus musculus] 68299 2816 12.98666667 12.44666667 -0.06127175 Down 0.170173756 Vps53 VPS53 GARP complex subunit K20299|1|0.0|1524|mmu:68299|vacuolar protein sorting-associated protein 53 GO:0043231//intracellular membrane-bounded organelle - GO:0045184//establishment of protein localization gi|31980873|ref|NP_080940.2|/0/vacuolar protein sorting-associated protein 53 homolog [Mus musculus] 212167 3745 0.663333333 0.786666667 0.246018429 Up 0.169966904 Gsap gamma-secretase activating protein - GO:0043231//intracellular membrane-bounded organelle - GO:0042987//amyloid precursor protein catabolic process;GO:0006508//proteolysis "gi|148671264|gb|EDL03211.1|/0/RIKEN cDNA A530088I07, isoform CRA_b, partial [Mus musculus]" 330216 1308 0.726666667 0.61 -0.252484486 Down 0.169966904 Mblac1 metallo-beta-lactamase domain containing 1 - - GO:0043169//cation binding;GO:0003824//catalytic activity - gi|29244490|ref|NP_808546.1|/1.39205e-145/metallo-beta-lactamase domain-containing protein 1 [Mus musculus] 231991 7886 0.77 0.646666667 -0.251836199 Down 0.169966904 Creb5 cAMP responsive element binding protein 5 K09047|1|0.0|717|rno:500131|cyclic AMP-responsive element-binding protein 5 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated" gi|674065684|ref|XP_008839746.1|/2.08754e-119/PREDICTED: cyclic AMP-responsive element-binding protein 5 isoform X4 [Nannospalax galili] 224691 2337 0.63 0.746666667 0.245112498 Up 0.169966904 Zfp472 zinc finger protein 472 K09228|1|0.0|1152|mmu:224691|KRAB domain-containing zinc finger protein GO:0044464 GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|162287111|ref|NP_694703.2|/0/zinc finger protein 472 [Mus musculus] 66597 1578 4.146666667 4.413333333 0.089916637 Up 0.169957501 Trim13 tripartite motif-containing 13 K12003|1|0.0|808|mmu:66597|tripartite motif-containing protein 13 [EC:2.3.2.27] GO:0031224//intrinsic component of membrane;GO:0044432;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0044432;GO:0031090//organelle membrane GO:0046914//transition metal ion binding;GO:0060089;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0060089;GO:0019787//ubiquitin-like protein transferase activity GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010212//response to ionizing radiation;GO:0008219//cell death;GO:0016567//protein ubiquitination;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010508//positive regulation of autophagy;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010212//response to ionizing radiation;GO:0008219//cell death;GO:0016567//protein ubiquitination;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010508//positive regulation of autophagy gi|14149754|ref|NP_075722.1|/0/E3 ubiquitin-protein ligase TRIM13 [Mus musculus] 19224 2881 4.29 4.023333333 -0.092586377 Down 0.169957501 Ptgs1 prostaglandin-endoperoxide synthase 1 K00509|1|0.0|1139|mmu:19224|prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1] - - - - 67168 2468 4.5 4.226666667 -0.090404662 Down 0.169957501 Lpar6 lysophosphatidic acid receptor 6 K04273|1|0.0|672|mmu:67168|lysophosphatidic acid receptor 6 GO:0031224//intrinsic component of membrane GO:0001608 GO:0035588 gi|532025265|ref|XP_005355664.1|/0/PREDICTED: lysophosphatidic acid receptor 6 [Microtus ochrogaster] 12418 5213 4.153333333 4.42 0.089776707 Up 0.169957501 Cbx4 chromobox 4 K11452|1|0.0|900|mmu:12418|chromobox protein 4 GO:0031519//PcG protein complex;GO:0044451 GO:0003723//RNA binding;GO:0042393//histone binding;GO:0000975//regulatory region DNA binding;GO:0003824//catalytic activity;GO:0032182//ubiquitin-like protein binding GO:0032446//protein modification by small protein conjugation;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter gi|161353508|ref|NP_031651.2|/0/E3 SUMO-protein ligase CBX4 [Mus musculus] 101401 6056 4.576666667 4.303333333 -0.088842625 Down 0.169957501 Adamts9 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9" K08624|1|0.0|2874|mmu:101401|a disintegrin and metalloproteinase with thrombospondin motifs 9 [EC:3.4.24.-] - - - gi|568940084|ref|XP_006505323.1|/0/PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 9 isoform X1 [Mus musculus] 78797 4757 4.01 4.276666667 0.092884528 Up 0.169957501 Ndor1 NADPH dependent diflavin oxidoreductase 1 "K15014|1|5e-98|358|aec:105145550|solute carrier family 29 (equilibrative nucleoside transporter), member 1/2/3" GO:0044424;GO:0044424 GO:0046914//transition metal ion binding;GO:0032553//ribonucleotide binding;GO:0046914//transition metal ion binding;GO:0032553//ribonucleotide binding GO:0044710;GO:0071310//cellular response to organic substance;GO:0044710;GO:0071310//cellular response to organic substance gi|126723293|ref|NP_001075945.1|/0/NADPH-dependent diflavin oxidoreductase 1 isoform 1 [Mus musculus] 68734 4568.16 4.763333333 4.49 -0.085256066 Down 0.169957501 Smek1 "SMEK homolog 1, suppressor of mek1 (Dictyostelium)" K17491|1|0.0|1466|mmu:68734|protein phosphatase 4 regulatory subunit 3 - - - - 240888 6815 0.453333333 0.353333333 -0.359542387 Down 0.169948099 Gpr161 G protein-coupled receptor 161 K08439|1|0.0|930|mmu:240888|G protein-coupled receptor 161 GO:0005929//cilium;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0005768//endosome;GO:0005929//cilium;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0005768//endosome GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0006171//cAMP biosynthetic process;GO:0032502//developmental process;GO:0045879//negative regulation of smoothened signaling pathway;GO:0006171//cAMP biosynthetic process;GO:0032502//developmental process;GO:0045879//negative regulation of smoothened signaling pathway gi|124487463|ref|NP_001074595.1|/0/G-protein coupled receptor 161 isoform 1 [Mus musculus] 238377 2938 0.356666667 0.456666667 0.356565097 Up 0.169948099 Gpr68 G protein-coupled receptor 68 K08408|1|0.0|729|mmu:238377|G protein-coupled receptor 68 GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway;GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway;GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway "gi|148686940|gb|EDL18887.1|/0/G protein-coupled receptor 68, isoform CRA_a [Mus musculus]" 100503307 1379 0.433333333 0.336666667 -0.36415633 Down 0.169948099 Gm15408 predicted gene 15408 - - - - "gi|148673910|gb|EDL05857.1|/1.21656e-46/mCG144569, partial [Mus musculus]" 209387 3770 0.336666667 0.433333333 0.36415633 Up 0.169948099 Trim30d tripartite motif-containing 30D K10648|1|0.0|640|mmu:209387|tripartite motif-containing protein 5 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated;GO:0001818//negative regulation of cytokine production;GO:0002224//toll-like receptor signaling pathway;GO:0031333//negative regulation of protein complex assembly;GO:0016567//protein ubiquitination;GO:0072593//reactive oxygen species metabolic process;GO:0009896;GO:0006351//transcription, DNA-templated;GO:0001818//negative regulation of cytokine production;GO:0002224//toll-like receptor signaling pathway;GO:0031333//negative regulation of protein complex assembly;GO:0016567//protein ubiquitination;GO:0072593//reactive oxygen species metabolic process;GO:0009896" gi|268370231|ref|NP_954597.2|/0/tripartite motif-containing 79 isoform 1 [Mus musculus] 244745 4753 1.596666667 1.433333333 -0.155688996 Down 0.169919892 Dpy19l1 dpy-19-like 1 (C. elegans) - GO:0031224//intrinsic component of membrane - - gi|169646320|ref|NP_766508.3|/0/probable C-mannosyltransferase DPY19L1 [Mus musculus] 11601 3560 1.516666667 1.353333333 -0.164386818 Down 0.169919892 Angpt2 angiopoietin 2 K05466|1|0.0|1007|mmu:11601|angiopoietin 2 GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044421 GO:0005126//cytokine receptor binding;GO:0043169//cation binding GO:0070848//response to growth factor;GO:0001525//angiogenesis;GO:0009888//tissue development;GO:0007599//hemostasis;GO:0048771//tissue remodeling;GO:0003006//developmental process involved in reproduction;GO:0050918//positive chemotaxis;GO:0007162//negative regulation of cell adhesion;GO:0048534//hematopoietic or lymphoid organ development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007565//female pregnancy;GO:0010596//negative regulation of endothelial cell migration;GO:0009628//response to abiotic stimulus;GO:0048869//cellular developmental process;GO:0009887//organ morphogenesis;GO:0009746;GO:0006950//response to stress gi|31982508|ref|NP_031452.2|/0/angiopoietin-2 precursor [Mus musculus] 217716 5499 1.423333333 1.586666667 0.156725504 Up 0.169919892 Mlh3 mutL homolog 3 K08739|1|0.0|2677|mmu:217716|DNA mismatch repair protein MLH3 GO:0000794//condensed nuclear chromosome;GO:0043073//germ cell nucleus;GO:0000794//condensed nuclear chromosome;GO:0043073//germ cell nucleus GO:0043565//sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding GO:0006281//DNA repair;GO:0007129//synapsis;GO:0033036;GO:0006281//DNA repair;GO:0007129//synapsis;GO:0033036 gi|124249062|ref|NP_780546.1|/0/DNA mismatch repair protein Mlh3 [Mus musculus] 66443 2365 1.376666667 1.533333333 0.15549208 Up 0.169919892 Tnfaip8l1 "tumor necrosis factor, alpha-induced protein 8-like 1" - - - - gi|31560244|ref|NP_079842.2|/7.05452e-86/tumor necrosis factor alpha-induced protein 8-like protein 1 [Mus musculus] 229363 4567 8.216666667 8.603333333 0.066342495 Up 0.169816465 Gmps guanine monophosphate synthetase K01951|1|0.0|1382|mmu:229363|GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] GO:0044444//cytoplasmic part "GO:0032550;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0005515//protein binding;GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides" GO:0006144//purine nucleobase metabolic process;GO:0009152//purine ribonucleotide biosynthetic process;GO:0009064//glutamine family amino acid metabolic process;GO:0009127//purine nucleoside monophosphate biosynthetic process;GO:0042221//response to chemical gi|85861218|ref|NP_001028472.2|/0/GMP synthase [glutamine-hydrolyzing] [Mus musculus] 13712 3548 7.796666667 8.186666667 0.070418699 Up 0.169816465 Elk1 "ELK1, member of ETS oncogene family" K04375|1|0.0|639|mmu:13712|ETS domain-containing protein Elk-1 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006366//transcription from RNA polymerase II promoter gi|836635|emb|CAA60715.1|/1.20886e-180/elk1 [Mus musculus] 66867 3562 7.833333333 8.223333333 0.070096959 Up 0.169816465 Hmg20a high mobility group 20A K09272|1|2e-10|71.2|dre:449949|structure-specific recognition protein 1;K10802|3|3e-10|70.9|mde:101897662|high mobility group protein B1 GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity GO:0006325//chromatin organization;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter "gi|148693919|gb|EDL25866.1|/0/high mobility group 20A, isoform CRA_b, partial [Mus musculus]" 67010 1833.73 7.703333333 8.093333333 0.071251162 Up 0.169816465 Rbm7 RNA binding motif protein 7 K13188|1|3e-140|263|mmu:67010|RNA-binding protein 7 - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0022403;GO:0022403 gi|27753952|ref|NP_659197.2|/4.9547e-150/RNA-binding protein 7 [Mus musculus] 69723 1213 8.376666667 7.99 -0.068180762 Down 0.169816465 Rpain RPA interacting protein - GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body GO:0043169//cation binding;GO:0005515//protein binding;GO:0043169//cation binding;GO:0005515//protein binding;GO:0043169//cation binding;GO:0005515//protein binding;GO:0043169//cation binding;GO:0005515//protein binding GO:0009416//response to light stimulus;GO:0006260//DNA replication;GO:0006886//intracellular protein transport;GO:0009416//response to light stimulus;GO:0006260//DNA replication;GO:0006886//intracellular protein transport;GO:0009416//response to light stimulus;GO:0006260//DNA replication;GO:0006886//intracellular protein transport;GO:0009416//response to light stimulus;GO:0006260//DNA replication;GO:0006886//intracellular protein transport gi|356991230|ref|NP_001239344.1|/1.41606e-84/RPA-interacting protein isoform 2 [Mus musculus] 229615 2956.26 8.106666667 8.496666667 0.067788145 Up 0.169816465 Pias3 protein inhibitor of activated STAT 3 K16064|1|0.0|1117|mmu:229615|E3 SUMO-protein ligase PIAS3 GO:0043005//neuron projection;GO:0016604//nuclear body;GO:0043005//neuron projection;GO:0016604//nuclear body;GO:0043005//neuron projection;GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0005515//protein binding;GO:0016247//channel regulator activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0005515//protein binding;GO:0016247//channel regulator activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0005515//protein binding;GO:0016247//channel regulator activity;GO:0019787//ubiquitin-like protein transferase activity "GO:0016925//protein sumoylation;GO:0009719;GO:0006351//transcription, DNA-templated;GO:0042391//regulation of membrane potential;GO:0016925//protein sumoylation;GO:0009719;GO:0006351//transcription, DNA-templated;GO:0042391//regulation of membrane potential;GO:0016925//protein sumoylation;GO:0009719;GO:0006351//transcription, DNA-templated;GO:0042391//regulation of membrane potential" "gi|148706965|gb|EDL38912.1|/0/protein inhibitor of activated STAT 3, isoform CRA_b, partial [Mus musculus]" 75423 5212 7.603333333 7.996666667 0.072766711 Up 0.169816465 Arl5a ADP-ribosylation factor-like 5A K07949|1|3e-99|367|mmu:75423|ADP-ribosylation factor-like protein 5A GO:0044464 GO:0032550 GO:0035556//intracellular signal transduction gi|33695144|ref|NP_892039.1|/2.30374e-98/ADP-ribosylation factor-like protein 5A [Mus musculus] 330401 5719 8.473333333 8.083333333 -0.067979283 Down 0.169816465 Tmcc1 transmembrane and coiled coil domains 1 K16288|1|2e-138|496|oaa:100076390|receptor-interacting serine/threonine-protein kinase 5 [EC:2.7.11.1] GO:0031224//intrinsic component of membrane - - gi|50510629|dbj|BAD32300.1|/0/mKIAA0779 protein [Mus musculus] 76267 3474 8.43 8.036666667 -0.068935386 Down 0.169816465 Fads1 fatty acid desaturase 1 K10224|1|0.0|875|mmu:76267|acyl-CoA (8-3)-desaturase (Delta-5 desaturase) [EC:1.14.19.44] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane GO:0046914//transition metal ion binding;GO:0016215//acyl-CoA desaturase activity;GO:0046906//tetrapyrrole binding "GO:0051234//establishment of localization;GO:0006351//transcription, DNA-templated;GO:0001676//long-chain fatty acid metabolic process;GO:0034285;GO:0006091//generation of precursor metabolites and energy;GO:0006633//fatty acid biosynthetic process;GO:0006690//icosanoid metabolic process;GO:0007154//cell communication;GO:0043434//response to peptide hormone;GO:0033273//response to vitamin;GO:0030154//cell differentiation;GO:0044767//single-organism developmental process;GO:0033554//cellular response to stress;GO:0006644//phospholipid metabolic process" gi|22164784|ref|NP_666206.1|/0/fatty acid desaturase 1 [Mus musculus] 56412 2303 13.13 12.60333333 -0.059061568 Down 0.169797661 Noa1 nitric oxide associated 1 K19832|1|0.0|1197|mmu:56412|nitric oxide-associated protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0032550 GO:0012501//programmed cell death;GO:0006412//translation;GO:0043467//regulation of generation of precursor metabolites and energy gi|9790049|ref|NP_062810.1|/0/nitric oxide-associated protein 1 [Mus musculus] 19027 4615 12.67333333 12.14333333 -0.061631537 Down 0.169797661 Sypl synaptophysin-like protein K14168|1|9e-40|169|fpg:101912737|cytoplasmic tRNA 2-thiolation protein 1 [EC:2.7.7.-] GO:0030136//clathrin-coated vesicle;GO:0012506//vesicle membrane;GO:0048770;GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle;GO:0012506//vesicle membrane;GO:0048770;GO:0016021//integral component of membrane - GO:0051234//establishment of localization;GO:0007267//cell-cell signaling;GO:0051234//establishment of localization;GO:0007267//cell-cell signaling gi|226958374|ref|NP_038663.2|/1.05977e-139/synaptophysin-like protein 1 isoform 1 [Mus musculus] 192169 1640 12.91 12.37666667 -0.060866186 Down 0.169797661 Ufsp2 UFM1-specific peptidase 2 K01376|1|0.0|907|mmu:192169|UFM1-specific protease 2 [EC:3.4.22.-] GO:0043231//intracellular membrane-bounded organelle "GO:0016788//hydrolase activity, acting on ester bonds;GO:0008234//cysteine-type peptidase activity" GO:0019538//protein metabolic process gi|20149754|ref|NP_619609.1|/0/ufm1-specific protease 2 [Mus musculus] 63958 5535 13.48333333 14.01666667 0.055966098 Up 0.169797661 Ube4b ubiquitination factor E4B K10597|1|0.0|2051|mmu:63958|ubiquitin conjugation factor E4 B [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding GO:0012501//programmed cell death;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0030030//cell projection organization;GO:0009416//response to light stimulus;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0016567//protein ubiquitination gi|28972347|dbj|BAC65627.1|/0/mKIAA0684 protein [Mus musculus] 14595 4535 32.26 31.23333333 -0.046659891 Down 0.169760051 B4galt1 "UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1" "K07966|1|0.0|776|mmu:14595|beta-1,4-galactosyltransferase 1 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]" GO:0005911//cell-cell junction;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0005903//brush border;GO:0030312//external encapsulating structure;GO:0044459;GO:0031985//Golgi cisterna GO:0035250//UDP-galactosyltransferase activity;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0015631//tubulin binding GO:0001525//angiogenesis;GO:0003006//developmental process involved in reproduction;GO:0007340//acrosome reaction;GO:0006928//movement of cell or subcellular component;GO:0008283//cell proliferation;GO:0048732//gland development;GO:0006915//apoptotic process;GO:0022603//regulation of anatomical structure morphogenesis;GO:0035036//sperm-egg recognition;GO:0009100//glycoprotein metabolic process;GO:0022610;GO:0042060//wound healing;GO:0019318//hexose metabolic process;GO:0060562//epithelial tube morphogenesis;GO:0006954//inflammatory response;GO:0006464//cellular protein modification process;GO:0002376//immune system process;GO:0030855//epithelial cell differentiation;GO:0043062//extracellular structure organization;GO:0005988 "gi|11602910|ref|NP_071641.1|/0/beta-1,4-galactosyltransferase 1 [Mus musculus]" 16159 1275 0.196666667 0.12 -0.712718048 Down 0.169760051 Il12a interleukin 12a K05406|1|1e-106|389|mmu:16159|interleukin 12A GO:0005615//extracellular space;GO:0044424;GO:0005615//extracellular space;GO:0044424 GO:0019972//interleukin-12 binding;GO:0005126//cytokine receptor binding;GO:0046983//protein dimerization activity;GO:0019972//interleukin-12 binding;GO:0005126//cytokine receptor binding;GO:0046983//protein dimerization activity GO:0032946//positive regulation of mononuclear cell proliferation;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0048870//cell motility;GO:0001562//response to protozoan;GO:0022402//cell cycle process;GO:0042742//defense response to bacterium;GO:0002420;GO:0030217//T cell differentiation;GO:0009411//response to UV;GO:0010661;GO:0046635//positive regulation of alpha-beta T cell activation;GO:0001819//positive regulation of cytokine production;GO:0042504;GO:0002237//response to molecule of bacterial origin;GO:0008285//negative regulation of cell proliferation;GO:0007155//cell adhesion;GO:0042098//T cell proliferation;GO:0001818//negative regulation of cytokine production;GO:0030101//natural killer cell activation;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0048870//cell motility;GO:0001562//response to protozoan;GO:0022402//cell cycle process;GO:0042742//defense response to bacterium;GO:0002420;GO:0030217//T cell differentiation;GO:0009411//response to UV;GO:0010661;GO:0046635//positive regulation of alpha-beta T cell activation;GO:0001819//positive regulation of cytokine production;GO:0042504;GO:0002237//response to molecule of bacterial origin;GO:0008285//negative regulation of cell proliferation;GO:0007155//cell adhesion;GO:0042098//T cell proliferation;GO:0001818//negative regulation of cytokine production;GO:0030101//natural killer cell activation gi|6680395|ref|NP_032377.1|/1.03382e-105/interleukin-12 subunit alpha isoform 2 precursor [Mus musculus] 93889 5039 0.126666667 0.206666667 0.706268797 Up 0.169760051 Pcdhb18 protocadherin beta 18 K16494|1|0.0|1476|mmu:93889|protocadherin beta - - - - 319448 6177 2.463333333 2.263333333 -0.12216279 Down 0.169722442 Fndc3a fibronectin type III domain containing 3A K12567|1|5e-65|253|sko:102801380|titin [EC:2.7.11.1] GO:0031224//intrinsic component of membrane;GO:0030141//secretory granule;GO:0012505//endomembrane system - GO:0007155//cell adhesion;GO:0007281//germ cell development "gi|148703921|gb|EDL35868.1|/0/fibronectin type III domain containing 3a, isoform CRA_a, partial [Mus musculus]" 117160 3456 2.52 2.316666667 -0.121373257 Down 0.169722442 Ttyh2 tweety family member 2 K02923|1|1e-176|623|cmy:102946987|large subunit ribosomal protein L38e;K10401|2|2e-11|74.7|nle:100603756|kinesin family member 18/19 GO:0034702//ion channel complex GO:0005253//anion channel activity GO:0015698//inorganic anion transport "gi|148702493|gb|EDL34440.1|/0/tweety homolog 2 (Drosophila), partial [Mus musculus]" 14168 2488.1 28.27333333 27.25 -0.053185752 Down 0.169562601 Fgf13 fibroblast growth factor 13 K04358|1|1e-146|523|pale:102882519|fibroblast growth factor GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0044291//cell-cell contact zone;GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0044291//cell-cell contact zone GO:0005102//receptor binding;GO:0015631//tubulin binding;GO:0019887//protein kinase regulator activity;GO:0016247//channel regulator activity;GO:0005102//receptor binding;GO:0015631//tubulin binding;GO:0019887//protein kinase regulator activity;GO:0016247//channel regulator activity GO:0030010//establishment of cell polarity;GO:0007009//plasma membrane organization;GO:0021987//cerebral cortex development;GO:0007611//learning or memory;GO:0016477//cell migration;GO:0001934//positive regulation of protein phosphorylation;GO:0030308//negative regulation of cell growth;GO:0012501//programmed cell death;GO:0007019//microtubule depolymerization;GO:0030010//establishment of cell polarity;GO:0007009//plasma membrane organization;GO:0021987//cerebral cortex development;GO:0007611//learning or memory;GO:0016477//cell migration;GO:0001934//positive regulation of protein phosphorylation;GO:0030308//negative regulation of cell growth;GO:0012501//programmed cell death;GO:0007019//microtubule depolymerization gi|16758168|ref|NP_445880.1|/5.07369e-106/fibroblast growth factor 13 [Rattus norvegicus] 19155 4161 28.46666667 29.48666667 0.050789172 Up 0.169562601 Npepps aminopeptidase puromycin sensitive K08776|1|0.0|1717|mmu:19155|puromycin-sensitive aminopeptidase [EC:3.4.11.-] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity GO:0016567//protein ubiquitination;GO:0001666//response to hypoxia;GO:0048002//antigen processing and presentation of peptide antigen gi|74228873|dbj|BAE21917.1|/0/unnamed protein product [Mus musculus] 16451 5299 31.19 32.20666667 0.046275799 Up 0.169562601 Jak1 Janus kinase 1 K11217|1|0.0|2289|mmu:16451|Janus kinase 1 [EC:2.7.10.2] GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0032550;GO:0048020//CCR chemokine receptor binding;GO:0004713//protein tyrosine kinase activity GO:0009636//response to toxic substance;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0007166//cell surface receptor signaling pathway gi|111607496|ref|NP_666257.2|/0/tyrosine-protein kinase JAK1 [Mus musculus] 69771 1571 0.133333333 0.216666667 0.700439718 Up 0.169534394 1810019D21Rik RIKEN cDNA 1810019D21 gene - - - - - 666938 7935 0.123333333 0.2 0.69743723 Up 0.169534394 Bend4 BEN domain containing 4 - - - - gi|261245031|ref|NP_001158278.1|/0/BEN domain-containing protein 4 [Mus musculus] 22036 2697 0.33 0.236666667 -0.479609501 Down 0.169515589 Traip TRAF-interacting protein K11985|1|0.0|926|mmu:22036|TRAF-interacting protein [EC:2.3.2.27] - - - - 574418 2570 31.34333333 32.35666667 0.045904374 Up 0.169430968 Serinc4 serine incorporator 4 - GO:0031224//intrinsic component of membrane - GO:0006644//phospholipid metabolic process "gi|148696114|gb|EDL28061.1|/0/hypothetical LOC574418, isoform CRA_b, partial [Mus musculus]" 12794 1361 0.333333333 0.24 -0.473931188 Down 0.169421565 Cnih2 cornichon family AMPA receptor auxiliary protein 2 K20368|1|2e-72|206|lve:103078401|protein cornichon - - - - 57748 8780 5.676666667 5.986666667 0.076708915 Up 0.169355749 Jmy junction-mediating and regulatory protein "K20479|1|3e-140|503|gga:415457|WASP homolog-associated protein with actin, membranes and microtubules" - - - - 68205 2143 11.93333333 12.45666667 0.061920976 Up 0.169252322 Urm1 ubiquitin related modifier 1 K12161|1|2e-52|210|pale:102886845|ubiquitin related modifier 1 GO:0044424 "GO:0016782//transferase activity, transferring sulfur-containing groups" GO:0006400//tRNA modification "gi|159163326|pdb|1WGK|A/2.02484e-52/Chain A, Solution Structure Of Mouse Hypothetical Protein 2900073h19rik" 217039 2967 12.57333333 13.09333333 0.058465254 Up 0.169252322 Ggnbp2 gametogenetin binding protein 2 - GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle - GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|564373609|ref|XP_006247115.1|/0/PREDICTED: gametogenetin-binding protein 2 isoform X8 [Rattus norvegicus] 69576 1267 26.85333333 27.85 0.052576145 Up 0.169233518 Smco1 single-pass membrane protein with coiled-coil domains 1 "K03847|1|8e-08|41.6|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - gi|281427239|ref|NP_899106.2|/1.86623e-115/single-pass membrane and coiled-coil domain-containing protein 1 [Mus musculus] 74499 2066 0.236666667 0.326666667 0.464962725 Up 0.169120689 Sost sclerostin K16834|1|1e-119|433|mmu:74499|sclerostin GO:0043231//intracellular membrane-bounded organelle;GO:0044421;GO:0031012//extracellular matrix GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding GO:0009605//response to external stimulus;GO:0006461//protein complex assembly;GO:0044707;GO:0030178//negative regulation of Wnt signaling pathway;GO:0032870//cellular response to hormone stimulus;GO:0030509//BMP signaling pathway gi|567316045|ref|NP_077769.4|/9.13478e-119/sclerostin precursor [Mus musculus] 103551 2349 1.036666667 1.18 0.18683478 Up 0.169017263 E130012A19Rik RIKEN cDNA E130012A19 gene - - - - gi|111185892|ref|NP_780541.2|/2.70804e-138/uncharacterized protein C17orf96 homolog [Mus musculus] 331188 4089 1.116666667 0.98 -0.188344941 Down 0.169017263 Zfp781 zinc finger protein 781 K09228|1|0.0|1501|mmu:100040944|KRAB domain-containing zinc finger protein - - - gi|755534736|ref|XP_011241796.1|/0/PREDICTED: zinc finger protein 781 isoform X2 [Mus musculus] 225392 1783 0.47 0.37 -0.345135486 Down 0.168979653 Rell2 RELT-like 2 K05156|1|5e-16|88.6|cmk:103177155|tumor necrosis factor receptor superfamily member 19-like GO:0031224//intrinsic component of membrane;GO:0005578//proteinaceous extracellular matrix GO:0005515//protein binding GO:0010810//regulation of cell-substrate adhesion gi|288541333|ref|NP_722488.2|/2.94633e-147/RELT-like protein 2 [Mus musculus] 20355 4040.92 0.353333333 0.45 0.348895142 Up 0.168979653 Sema4f "sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain" K06521|1|0.0|1325|mmu:20355|semaphorin 4 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0097060//synaptic membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0097060//synaptic membrane GO:0005488//binding;GO:0005488//binding GO:0007411//axon guidance;GO:0030308//negative regulation of cell growth;GO:0007411//axon guidance;GO:0030308//negative regulation of cell growth gi|4104675|gb|AAD02103.1|/0/semaphorin M [Mus musculus] 22719 2347 1.15 1.296666667 0.173173793 Up 0.168923239 Zfp61 zinc finger protein 61 K09228|1|0.0|1179|mmu:22719|KRAB domain-containing zinc finger protein - - - gi|121247404|ref|NP_033587.2|/0/zinc finger protein 61 [Mus musculus] 73166 1496 1.26 1.413333333 0.16567803 Up 0.168923239 Tm7sf2 transmembrane 7 superfamily member 2 K00222|1|0.0|689|mmu:73166|Delta14-sterol reductase [EC:1.3.1.70] GO:0043227//membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor" GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process gi|117414164|ref|NP_082730.2|/0/delta(14)-sterol reductase [Mus musculus] 12166 5481 7.93 7.546666667 -0.071481314 Down 0.168904434 Bmpr1a "bone morphogenetic protein receptor, type 1A" K04673|1|0.0|1076|mmu:12166|bone morphogenetic protein receptor type-1A [EC:2.7.11.30] GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0044459;GO:0044297//cell body "GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0032550;GO:0042802//identical protein binding;GO:0043169//cation binding" GO:0030326//embryonic limb morphogenesis;GO:0001935//endothelial cell proliferation;GO:0007184//SMAD protein import into nucleus;GO:0008284//positive regulation of cell proliferation;GO:0001501//skeletal system development;GO:0030282//bone mineralization;GO:0003006//developmental process involved in reproduction;GO:0009952//anterior/posterior pattern specification;GO:0043009//chordate embryonic development;GO:0003203//endocardial cushion morphogenesis;GO:0042476//odontogenesis;GO:0021536//diencephalon development;GO:0001934//positive regulation of protein phosphorylation;GO:0009798//axis specification;GO:0001649//osteoblast differentiation;GO:0040007//growth;GO:0007492//endoderm development;GO:0030856//regulation of epithelial cell differentiation;GO:0002376//immune system process;GO:0060897;GO:0006366//transcription from RNA polymerase II promoter;GO:0048338;GO:0030323//respiratory tube development;GO:0042661//regulation of mesodermal cell fate specification;GO:0014031//mesenchymal cell development;GO:0010721//negative regulation of cell development gi|46519168|ref|NP_033888.2|/0/bone morphogenetic protein receptor type-1A precursor [Mus musculus] 14885 1685 8.293333333 8.676666667 0.065188826 Up 0.168904434 Gtf2h4 "general transcription factor II H, polypeptide 4" K03144|1|0.0|872|mmu:14885|transcription initiation factor TFIIH subunit 4 GO:0005667//transcription factor complex "GO:0003678//DNA helicase activity;GO:0004674//protein serine/threonine kinase activity;GO:0042623//ATPase activity, coupled" "GO:0006281//DNA repair;GO:0006464//cellular protein modification process;GO:0006351//transcription, DNA-templated" gi|6754094|ref|NP_034494.1|/0/general transcription factor IIH subunit 4 [Mus musculus] 67776 4129.93 7.89 7.51 -0.071212392 Down 0.168904434 Vwa5a von Willebrand factor A domain containing 5A K18466|1|3e-68|263|smm:Smp_073130.2|vacuolar protein sorting-associated protein 26;K10798|4|2e-62|244|aqu:100633591|poly [ADP-ribose] polymerase [EC:2.4.2.30] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - - "gi|148693525|gb|EDL25472.1|/0/loss of heterozygosity, 11, chromosomal region 2, gene A homolog (human), isoform CRA_b, partial [Mus musculus]" 67037 1076.43 11.96333333 12.47666667 0.060613125 Up 0.16884802 Pmf1 polyamine-modulated factor 1 K11546|1|5e-87|323|mmu:67037|polyamine-modulated factor 1 "GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region" GO:0003712//transcription cofactor activity;GO:0030275//LRR domain binding;GO:0003712//transcription cofactor activity;GO:0030275//LRR domain binding "GO:0000087//mitotic M phase;GO:0006351//transcription, DNA-templated;GO:0000087//mitotic M phase;GO:0006351//transcription, DNA-templated" gi|13385420|ref|NP_080204.1|/4.20972e-86/polyamine-modulated factor 1 isoform 1 [Mus musculus] 227737 3693 12.62666667 12.11666667 -0.059480967 Down 0.16884802 Fam129b "family with sequence similarity 129, member B" - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0070161 GO:0008289//lipid binding GO:0006915//apoptotic process gi|22122641|ref|NP_666231.1|/0/niban-like protein 1 [Mus musculus] 67078 1038 30.79 29.82 -0.04618161 Down 0.168838617 Pgp phosphoglycolate phosphatase K19269|1|1e-174|614|mmu:67078|phosphoglycolate phosphatase [EC:3.1.3.18 3.1.3.48] - GO:0016791//phosphatase activity GO:0044238//primary metabolic process gi|40254507|ref|NP_080230.2|/1.10973e-173/phosphoglycolate phosphatase [Mus musculus] 55981 2193 3.246666667 3.48 0.100128034 Up 0.168801008 Pigb "phosphatidylinositol glycan anchor biosynthesis, class B" "K05286|1|0.0|1108|mmu:55981|phosphatidylinositol glycan, class B [EC:2.4.1.-]" GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane GO:0016740//transferase activity GO:0006664//glycolipid metabolic process;GO:0006497//protein lipidation gi|167900468|ref|NP_061377.2|/0/GPI mannosyltransferase 3 [Mus musculus] 218543 4063 3.333333333 3.566666667 0.097610797 Up 0.168801008 Srek1 splicing regulatory glutamine/lysine-rich protein 1 "K13165|1|2e-105|386|cge:100774662|splicing factor, arginine/serine-rich 12" - - - - 70646 4429 3.506666667 3.276666667 -0.097871383 Down 0.168801008 Naa30 "N(alpha)-acetyltransferase 30, NatC catalytic subunit" K00670|1|1e-138|497|mmu:70646|peptide alpha-N-acetyltransferase [EC:2.3.1.88] - GO:0008080//N-acetyltransferase activity - gi|940870993|ref|NP_081768.2|/9.47416e-138/N-alpha-acetyltransferase 30 [Mus musculus] 78455 6240 3.446666667 3.213333333 -0.101131134 Down 0.168801008 Helz helicase with zinc finger domain K18422|1|1e-57|228|tru:101067721|helicase MOV-10 [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 - gi|50355943|ref|NP_938040.1|/0/probable helicase with zinc finger domain [Mus musculus] 231866 5265.82 3.356666667 3.123333333 -0.10394273 Down 0.168801008 Zfp12 zinc finger protein 12 K09228|1|0.0|1374|mmu:231866|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|29244112|ref|NP_808349.1|/0/zinc finger protein 12 isoform 2 [Mus musculus] 20321 2508 0.78 0.66 -0.2410081 Down 0.168744594 Frrs1 ferric-chelate reductase 1 K12349|1|3e-32|143|smm:Smp_147460|neutral ceramidase [EC:3.5.1.23];K12589|2|1e-26|124|dse:Dsec_GM21652|exosome complex component RRP42;K02599|3|1e-12|77.8|sko:100371085|Notch GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane "GO:0016723//oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor;GO:0043169//cation binding;GO:0016723//oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor;GO:0043169//cation binding" GO:0044710;GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy;GO:0044710;GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy gi|164698442|ref|NP_033172.2|/0/ferric-chelate reductase 1 precursor [Mus musculus] 12055 981 25.52 26.47666667 0.053093173 Up 0.16865057 Bcl7c B cell CLL/lymphoma 7C - - - - gi|6753176|ref|NP_033876.1|/2.8035e-91/B-cell CLL/lymphoma 7 protein family member C [Mus musculus] 18591 2956 31.3 30.33666667 -0.045100083 Down 0.16865057 Pdgfb "platelet derived growth factor, B polypeptide" K17386|1|2e-114|416|mmu:18591|platelet-derived growth factor subunit B GO:0031091//platelet alpha granule;GO:0012505//endomembrane system;GO:0044459;GO:0044432 GO:0042802//identical protein binding;GO:0070851//growth factor receptor binding;GO:0008047//enzyme activator activity;GO:0019838//growth factor binding;GO:0046983//protein dimerization activity "GO:0007067//mitotic nuclear division;GO:0010543//regulation of platelet activation;GO:0001701//in utero embryonic development;GO:0030595//leukocyte chemotaxis;GO:1900238;GO:0071407//cellular response to organic cyclic compound;GO:0043434//response to peptide hormone;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0038089//positive regulation of cell migration by vascular endothelial growth factor signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0022607//cellular component assembly;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0042311//vasodilation;GO:0007010//cytoskeleton organization;GO:0007267//cell-cell signaling;GO:0010595//positive regulation of endothelial cell migration;GO:0072110//glomerular mesangial cell proliferation;GO:0035051//cardiocyte differentiation;GO:0006260//DNA replication;GO:0006351//transcription, DNA-templated;GO:0072144//glomerular mesangial cell development;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0043627//response to estrogen;GO:0072593//reactive oxygen species metabolic process;GO:0034767//positive regulation of ion transmembrane transport;GO:0040007//growth;GO:0048534//hematopoietic or lymphoid organ development;GO:0001935//endothelial cell proliferation;GO:0019229//regulation of vasoconstriction;GO:0007435//salivary gland morphogenesis;GO:0043410//positive regulation of MAPK cascade;GO:0072011//glomerular endothelium development;GO:0006887//exocytosis;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032147//activation of protein kinase activity;GO:0006661//phosphatidylinositol biosynthetic process;GO:0003093//regulation of glomerular filtration;GO:0043405//regulation of MAP kinase activity;GO:0014909//smooth muscle cell migration" gi|40538817|ref|NP_035187.2|/1.35617e-113/platelet-derived growth factor subunit B precursor [Mus musculus] 330908 6002 0.216666667 0.136666667 -0.664815808 Down 0.168631765 Opcml opioid binding protein/cell adhesion molecule-like K06773|1|0.0|665|mmu:330908|opioid binding protein/cell adhesion molecule-like GO:0016021//integral component of membrane GO:0008528//G-protein coupled peptide receptor activity GO:0008037//cell recognition;GO:0007186//G-protein coupled receptor signaling pathway gi|829926203|ref|XP_012595084.1|/0/PREDICTED: opioid-binding protein/cell adhesion molecule isoform X4 [Microcebus murinus] 234421 646 0.323333333 0.236666667 -0.450165723 Down 0.16861296 Cib3 calcium and integrin binding family member 3 K17259|1|1e-36|154|bfo:BRAFLDRAFT_125227|calcium and integrin-binding protein 1 - - - gi|537263449|gb|ERE90447.1|/5.238e-95/calcium and integrin-binding family member 3-like isoform 1 [Cricetulus griseus] 234734 3728 29.96 30.91333333 0.045191602 Up 0.168500132 Aars alanyl-tRNA synthetase K01872|1|0.0|1859|mmu:234734|alanyl-tRNA synthetase [EC:6.1.1.7] GO:0044424 GO:0032550;GO:0031406//carboxylic acid binding;GO:0052689//carboxylic ester hydrolase activity;GO:0043169//cation binding;GO:0003723//RNA binding;GO:0004812//aminoacyl-tRNA ligase activity GO:0006984//ER-nucleus signaling pathway;GO:0008544//epidermis development;GO:0043066//negative regulation of apoptotic process;GO:0006418//tRNA aminoacylation for protein translation;GO:0008033//tRNA processing;GO:0001101//response to acid chemical;GO:0021695//cerebellar cortex development;GO:0006986//response to unfolded protein;GO:0050905//neuromuscular process;GO:0006448//regulation of translational elongation "gi|148679537|gb|EDL11484.1|/0/alanyl-tRNA synthetase, isoform CRA_a, partial [Mus musculus]" 100503386 3037 1.65 1.816666667 0.138827705 Up 0.16845312 Tpbgl trophoblast glycoprotein-like K06839|1|5e-08|63.2|phu:Phum_PHUM419730|slit 2;K08129|3|5e-07|59.7|oaa:103170217|nyctalopin;K18808|4|9e-07|58.9|fpg:101913268|toll-like receptor 13;K16659|5|1e-06|58.2|ola:101175083|reticulon-4 receptor - - - - 18710 5004 1.876666667 1.703333333 -0.139811631 Down 0.16845312 Pik3r3 "phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)" "K02649|1|0.0|912|mmu:18710|phosphoinositide-3-kinase, regulatory subunit" GO:0043234//protein complex GO:0035014//phosphatidylinositol 3-kinase regulator activity GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0043550//regulation of lipid kinase activity gi|568928613|ref|XP_006502922.1|/0/PREDICTED: phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [Mus musculus] 12912 8403.04 1.75 1.923333333 0.136253896 Up 0.16845312 Creb1 cAMP responsive element binding protein 1 K05870|1|4e-141|506|ssc:397449|cyclic AMP-responsive element-binding protein 1 GO:0000790//nuclear chromatin;GO:0043234//protein complex;GO:0000790//nuclear chromatin;GO:0043234//protein complex "GO:0001085//RNA polymerase II transcription factor binding;GO:0043566//structure-specific DNA binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0043566//structure-specific DNA binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding" "GO:0045892//negative regulation of transcription, DNA-templated;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006915//apoptotic process;GO:0060487//lung epithelial cell differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0048017//inositol lipid-mediated signaling;GO:0048732//gland development;GO:0008610//lipid biosynthetic process;GO:0045898//regulation of RNA polymerase II transcriptional preinitiation complex assembly;GO:0010863//positive regulation of phospholipase C activity;GO:0035264//multicellular organism growth;GO:0007589//body fluid secretion;GO:0021536//diencephalon development;GO:0045444//fat cell differentiation;GO:0006935//chemotaxis;GO:0070848//response to growth factor;GO:0046879//hormone secretion;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007623//circadian rhythm;GO:0006464//cellular protein modification process;GO:0038127//ERBB signaling pathway;GO:0032907//transforming growth factor beta3 production;GO:0032535//regulation of cellular component size;GO:0000165//MAPK cascade;GO:0031647//regulation of protein stability;GO:0016050//vesicle organization;GO:0045892//negative regulation of transcription, DNA-templated;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006915//apoptotic process;GO:0060487//lung epithelial cell differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0048017//inositol lipid-mediated signaling;GO:0048732//gland development;GO:0008610//lipid biosynthetic process;GO:0045898//regulation of RNA polymerase II transcriptional preinitiation complex assembly;GO:0010863//positive regulation of phospholipase C activity;GO:0035264//multicellular organism growth;GO:0007589//body fluid secretion;GO:0021536//diencephalon development;GO:0045444//fat cell differentiation;GO:0006935//chemotaxis;GO:0070848//response to growth factor;GO:0046879//hormone secretion;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007623//circadian rhythm;GO:0006464//cellular protein modification process;GO:0038127//ERBB signaling pathway;GO:0032907//transforming growth factor beta3 production;GO:0032535//regulation of cellular component size;GO:0000165//MAPK cascade;GO:0031647//regulation of protein stability;GO:0016050//vesicle organization" gi|82546874|ref|NP_598589.2|/1.05989e-140/cyclic AMP-responsive element-binding protein 1 isoform A [Mus musculus] 208967 3899 1.67 1.84 0.139857664 Up 0.16845312 Thnsl1 threonine synthase-like 1 (bacterial) - - GO:0016838;GO:0016301//kinase activity;GO:0032550;GO:0016838;GO:0016301//kinase activity;GO:0032550 GO:0006566//threonine metabolic process;GO:0006566//threonine metabolic process "gi|148676184|gb|EDL08131.1|/0/threonine synthase-like 1 (bacterial), isoform CRA_b, partial [Mus musculus]" 14017 1628.29 1.753333333 1.586666667 -0.144101226 Down 0.16845312 Evi2a ecotropic viral integration site 2a - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|6753786|ref|NP_034291.1|/5.95561e-122/protein EVI2A precursor [Mus musculus] 109241 6296.27 1.59 1.756666667 0.143813696 Up 0.16845312 Mbd5 methyl-CpG binding domain protein 5 - GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0003676//nucleic acid binding - gi|594591575|ref|NP_001277585.1|/0/methyl-CpG-binding domain protein 5 isoform b [Mus musculus] 52696 1860.07 28.75 29.69 0.046415137 Up 0.168330889 Zwint ZW10 interactor K19943|1|1e-125|452|mmu:52696|ZW10 interactor GO:0000776//kinetochore;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding GO:0051234//establishment of localization;GO:0000075//cell cycle checkpoint;GO:0000087//mitotic M phase gi|21326440|ref|NP_079911.1|/1.55183e-124/ZW10 interactor [Mus musculus] 100503248 676 0.383333333 0.486666667 0.344334508 Up 0.16825567 Gm15179 predicted gene 15179 - - - - - 16648 4167 11.96333333 12.46 0.058684646 Up 0.168246267 Kpna3 karyopherin (importin) alpha 3 K15043|1|5e-157|558|crg:105330652|importin subunit alpha-2 GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0005635//nuclear envelope GO:0022892//substrate-specific transporter activity;GO:0005048//signal sequence binding;GO:0005515//protein binding GO:0006606//protein import into nucleus;GO:0007166//cell surface receptor signaling pathway;GO:0019048//modulation by virus of host morphology or physiology;GO:0065003 gi|6680596|ref|NP_032492.1|/0/importin subunit alpha-4 [Mus musculus] 245880 2685 0.33 0.243333333 -0.439532061 Down 0.16821806 Wasf3 "WAS protein family, member 3" "K06083|1|0.0|796|mmu:245880|WAS protein family, member 3" GO:0043232;GO:0031252//cell leading edge GO:0008092//cytoskeletal protein binding GO:0031641//regulation of myelination;GO:0022604//regulation of cell morphogenesis;GO:0008154//actin polymerization or depolymerization;GO:0021782//glial cell development;GO:0065003;GO:0030031//cell projection assembly "gi|148673857|gb|EDL05804.1|/0/WAS protein family, member 3 [Mus musculus]" 71722 7148.21 25.14666667 26.07333333 0.05220786 Up 0.168199255 Cic capicua transcriptional repressor K20225|1|0.0|3433|mmu:71722|capicua transcriptional repressor - - - - 225898 3194 5.596666667 5.9 0.07614713 Up 0.168161646 Eml3 echinoderm microtubule associated protein like 3 K18596|1|0.0|1542|mmu:225898|echinoderm microtubule-associated protein-like 3 GO:0015630//microtubule cytoskeleton GO:0004175//endopeptidase activity GO:0019538//protein metabolic process "gi|148701458|gb|EDL33405.1|/0/echinoderm microtubule associated protein like 3, isoform CRA_b, partial [Mus musculus]" 231503 3100 5.563333333 5.263333333 -0.079972784 Down 0.168161646 Tmem150c transmembrane protein 150C - GO:0031224//intrinsic component of membrane - - gi|685541126|ref|XP_003898742.2|/2.05122e-128/PREDICTED: transmembrane protein 150C [Papio anubis] 27999 2739 4.893333333 5.19 0.084916976 Up 0.168161646 Fam3c "family with sequence similarity 3, member C" "K07747|1|1e-38|164|aam:106494905|beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:3.4.23.45];K09666|2|1e-22|111|hro:HELRODRAFT_188882|beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.-]" GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle - GO:0032502//developmental process gi|755515417|ref|XP_006505164.2|/2.56804e-127/PREDICTED: protein FAM3C isoform X2 [Mus musculus] 100504429 1015 0.01 0.056666667 2.502500341 Up 0.168133439 Spin2d "spindlin family, member 2D" - - - - gi|569010961|ref|XP_995303.3|/1.4374e-178/PREDICTED: spindlin-2A-like [Mus musculus] 394430 3242 0.01 0.056666667 2.502500341 Up 0.168133439 Ugt1a10 "UDP glycosyltransferase 1 family, polypeptide A10" K00699|1|0.0|1087|mmu:394430|glucuronosyltransferase [EC:2.4.1.17] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0042802//identical protein binding;GO:0030234//enzyme regulator activity;GO:0046983//protein dimerization activity;GO:0008194//UDP-glycosyltransferase activity GO:0006631//fatty acid metabolic process;GO:0009804//coumarin metabolic process;GO:0006706//steroid catabolic process;GO:0044092//negative regulation of molecular function;GO:0006805//xenobiotic metabolic process;GO:0009812//flavonoid metabolic process;GO:0006464//cellular protein modification process;GO:0014070//response to organic cyclic compound "gi|145864477|ref|NP_964003.2|/0/UDP glycosyltransferase 1 family, polypeptide A10 precursor [Mus musculus]" 73032 1032 0.056666667 0.01 -2.502500341 Down 0.168133439 Ttc9b tetratricopeptide repeat domain 9B K09572|1|4e-07|58.2|spu:764741|FK506-binding protein 6 [EC:5.2.1.8];K05864|3|3e-06|55.1|mze:101468696|peptidyl-prolyl isomerase D [EC:5.2.1.8] - - - gi|110625933|ref|NP_082693.1|/3.07776e-91/tetratricopeptide repeat protein 9B [Mus musculus] 546729 1047 0.056666667 0.01 -2.502500341 Down 0.168133439 Calhm1 calcium homeostasis modulator 1 K19738|1|1e-171|604|mmu:546729|calcium homeostasis modulator protein 1 - - - - 56872 1016 0.056666667 0.01 -2.502500341 Down 0.168133439 Pate4 prostate and testis expressed 4 - GO:0044421 GO:0005515//protein binding GO:0007268//chemical synaptic transmission;GO:0006950//response to stress gi|755529032|ref|XP_011240882.1|/3.56054e-60/PREDICTED: prostate and testis expressed protein 4 isoform X1 [Mus musculus] 20526 2571 0.01 0.056666667 2.502500341 Up 0.168133439 Slc2a2 "solute carrier family 2 (facilitated glucose transporter), member 2" "K07593|1|0.0|969|mmu:20526|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005903//brush border;GO:0044459;GO:0044444//cytoplasmic part GO:0005355//glucose transmembrane transporter activity;GO:0051183//vitamin transporter activity GO:0044763;GO:0009725//response to hormone;GO:0009746;GO:0008645//hexose transport;GO:0015711//organic anion transport "gi|165377237|ref|NP_112474.2|/0/solute carrier family 2, facilitated glucose transporter member 2 [Mus musculus]" 347710 2399 0.01 0.056666667 2.502500341 Up 0.168133439 Pramel4 preferentially expressed antigen in melanoma like 4 K10308|1|1e-09|68.2|myd:102753733|F-box protein 31 - - - gi|29789885|gb|AAO84499.2|/0/PRAME15 [Mus musculus] 57394 1019 0.01 0.056666667 2.502500341 Up 0.168133439 Tmem27 transmembrane protein 27 K20004|1|5e-55|217|phd:102324228|collectrin GO:0031224//intrinsic component of membrane GO:0008238//exopeptidase activity GO:0019538//protein metabolic process gi|10181182|ref|NP_065651.1|/3.36869e-125/collectrin isoform 1 precursor [Mus musculus] 16891 3787 0.01 0.056666667 2.502500341 Up 0.168133439 Lipg "lipase, endothelial" K01046|1|0.0|1042|mmu:16891|triacylglycerol lipase [EC:3.1.1.3] GO:0044421 GO:0004620//phospholipase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0005539//glycosaminoglycan binding GO:0055092//sterol homeostasis;GO:0006629//lipid metabolic process;GO:0031323//regulation of cellular metabolic process;GO:0031667//response to nutrient levels;GO:0030301//cholesterol transport;GO:0034369//plasma lipoprotein particle remodeling;GO:0010982 gi|188219561|ref|NP_034850.3|/0/endothelial lipase precursor [Mus musculus] 71149 1092 0.056666667 0.01 -2.502500341 Down 0.168133439 4933413G19Rik RIKEN cDNA 4933413G19 gene K13215|1|7e-60|233|rro:104659021|nuclear receptor-interacting protein 2 - - - gi|161353469|ref|NP_081973.1|/4.02035e-161/uncharacterized protein ENSP00000372125 homolog [Mus musculus] 381359 2471 0.01 0.056666667 2.502500341 Up 0.168133439 Prdm12 PR domain containing 12 K12463|1|2e-31|140|obi:106879018|PR domain zinc finger protein 4 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0007399//nervous system development;GO:0006351//transcription, DNA-templated" gi|182765475|ref|NP_001116834.1|/0/PR domain zinc finger protein 12 [Mus musculus] 58187 852 0.01 0.056666667 2.502500341 Up 0.168133439 Cldn10 claudin 10 K06087|1|1e-128|461|cge:100762571|claudin GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane - - "gi|148668249|gb|EDL00579.1|/1.2019e-111/claudin 10, isoform CRA_c, partial [Mus musculus]" 71996 840 0.01 0.056666667 2.502500341 Up 0.168133439 Fthl17a "ferritin, heavy polypeptide-like 17, member A" K00522|1|1e-51|205|ngi:103725435|ferritin heavy chain [EC:1.16.3.2] - GO:0046872//metal ion binding - gi|254675294|ref|NP_082322.1|/1.79832e-98/uncharacterized protein LOC71996 [Mus musculus] 330122 1018 0.056666667 0.01 -2.502500341 Down 0.168133439 Cxcl3 chemokine (C-X-C motif) ligand 3 K05505|1|6e-36|153|mmu:330122|C-X-C motif chemokine 1/2/3 GO:0044421 GO:0005125//cytokine activity GO:0006952//defense response;GO:0010212//response to ionizing radiation;GO:0008219//cell death;GO:0043627//response to estrogen;GO:0009611//response to wounding;GO:0031960//response to corticosteroid;GO:0070555//response to interleukin-1;GO:0032496//response to lipopolysaccharide;GO:0030595//leukocyte chemotaxis;GO:0051480//regulation of cytosolic calcium ion concentration gi|42600573|ref|NP_976065.1|/5.20372e-35/C-X-C motif chemokine 3 precursor [Mus musculus] 73616 853 0.01 0.056666667 2.502500341 Up 0.168133439 Pldi polymorphic derived intron containing - - - - - 238076 2870 0.056666667 0.01 -2.502500341 Down 0.168133439 Kcns3 "potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3" K04933|1|0.0|913|mmu:238076|potassium voltage-gated channel delayed-rectifier subfamily S member 3 GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity GO:0051259//protein oligomerization;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0051259//protein oligomerization;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|27734146|ref|NP_775593.1|/0/potassium voltage-gated channel subfamily S member 3 [Mus musculus] 13404 1852 0.056666667 0.01 -2.502500341 Down 0.168133439 Dmc1 DNA meiotic recombinase 1 K10872|1|5e-103|201|aam:106488490|meiotic recombination protein DMC1 - - - - 210741 1952 0.056666667 0.01 -2.502500341 Down 0.168133439 Kcnk12 "potassium channel, subfamily K, member 12" K04921|1|0.0|711|mmu:210741|potassium channel subfamily K member 12 GO:0031224//intrinsic component of membrane GO:0005261//cation channel activity GO:0044765//single-organism transport gi|40445393|ref|NP_954859.1|/0/potassium channel subfamily K member 12 [Mus musculus] 68354 941 0.01 0.056666667 2.502500341 Up 0.168133439 Plekhd1os "pleckstrin homology domain containing, family D (with coiled-coil domains) member 1, opposite strand" - - - - gi|148670730|gb|EDL02677.1|/1.3998e-76/mCG1027832 [Mus musculus] 242662 977 0.01 0.056666667 2.502500341 Up 0.168133439 Rims3 regulating synaptic membrane exocytosis 3 K15298|1|2e-154|547|mmu:242662|regulating synaptic membrane exocytosis protein 3 - GO:0005515//protein binding GO:0016079//synaptic vesicle exocytosis;GO:0006873//cellular ion homeostasis gi|33859823|ref|NP_891559.1|/1.50185e-153/regulating synaptic membrane exocytosis protein 3 [Mus musculus] 17927 1854 0.056666667 0.01 -2.502500341 Down 0.168133439 Myod1 myogenic differentiation 1 K09064|1|4e-147|524|mmu:17927|myogenic factor 3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043292//contractile fiber "GO:0044389//ubiquitin-like protein ligase binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding" "GO:0060143//positive regulation of syncytium formation by plasma membrane fusion;GO:0006366//transcription from RNA polymerase II promoter;GO:0043501//skeletal muscle adaptation;GO:0070887//cellular response to chemical stimulus;GO:0014902//myotube differentiation;GO:0051384//response to glucocorticoid;GO:0043403//skeletal muscle tissue regeneration;GO:0001709//cell fate determination;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0033554//cellular response to stress" gi|170172579|ref|NP_034996.2|/3.43323e-146/myoblast determination protein 1 [Mus musculus] 237300 2355 0.01 0.056666667 2.502500341 Up 0.168133439 Gm4922 predicted gene 4922 K08798|1|6e-116|421|cge:100775051|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|29244156|ref|NP_808374.1|/0/sperm motility kinase Z [Mus musculus] 217125 3334 2.653333333 2.863333333 0.109889701 Up 0.168133439 Samd14 sterile alpha motif domain containing 14 K17551|1|9e-165|583|ptr:101059659|neurabin - - - gi|568973293|ref|XP_006533074.1|/1.72743e-172/PREDICTED: sterile alpha motif domain-containing protein 14 isoform X2 [Mus musculus] 242646 982 0.01 0.056666667 2.502500341 Up 0.168133439 Tctex1d4 Tctex1 domain containing 4 "K06085|1|1e-08|62.8|nve:NEMVE_v1g242105|synovial sarcoma, X breakpoint 2 interacting protein;K11262|2|1e-06|56.2|aag:AaeL_AAEL006307|acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14]" - - - gi|33239425|ref|NP_778195.1|/8.40205e-104/tctex1 domain-containing protein 4 [Mus musculus] 72701 2868 0.01 0.056666667 2.502500341 Up 0.168133439 Zfp618 zinc finger protein 618 K09228|1|1e-11|74.7|myd:102772612|KRAB domain-containing zinc finger protein - - - gi|242397406|ref|NP_082602.1|/0/zinc finger protein 618 [Mus musculus] 13082 1781 0.01 0.056666667 2.502500341 Up 0.168133439 Cyp26a1 "cytochrome P450, family 26, subfamily a, polypeptide 1" "K07437|1|0.0|963|mmu:13082|cytochrome P450, family 26, subfamily A" GO:0043231//intracellular membrane-bounded organelle GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0004497//monooxygenase activity GO:0003002//regionalization;GO:0030522//intracellular receptor signaling pathway;GO:0001523//retinoid metabolic process;GO:0007399//nervous system development;GO:0014031//mesenchymal cell development;GO:0016103 gi|178057351|ref|NP_031837.2|/0/cytochrome P450 26A1 [Mus musculus] 93879 2340 0.056666667 0.01 -2.502500341 Down 0.168133439 Pcdhb8 protocadherin beta 8 K16494|1|0.0|1465|mmu:93879|protocadherin beta GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|16716433|ref|NP_444363.1|/0/protocadherin beta 8 precursor [Mus musculus] 258356 951 0.01 0.056666667 2.502500341 Up 0.168133439 Olfr564 olfactory receptor 564 K04257|1|2e-175|617|mmu:258356|olfactory receptor GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007608//sensory perception of smell gi|145699107|ref|NP_666471.2|/1.48834e-174/olfactory receptor 564 [Mus musculus] 100502887 975 0.056666667 0.01 -2.502500341 Down 0.168133439 Olfr331 olfactory receptor 331 K04257|1|7e-148|525|mmu:258261|olfactory receptor - - - - 259023 1041 0.01 0.056666667 2.502500341 Up 0.168133439 Olfr1055 olfactory receptor 1055 K04257|1|2e-163|577|mmu:259023|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|22128897|ref|NP_667232.1|/3.65353e-165/olfactory receptor 1055 isoform b [Mus musculus] 258462 1026 0.056666667 0.01 -2.502500341 Down 0.168133439 Olfr1392 olfactory receptor 1392 K04257|1|1e-155|551|mmu:258462|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|22203771|ref|NP_666681.1|/8.65974e-155/olfactory receptor 1392 [Mus musculus] 100038489 990 0.01 0.056666667 2.502500341 Up 0.168133439 Apela apelin receptor early endogenous ligand - - - - gi|74182886|dbj|BAE20426.1|/3.53173e-41/unnamed protein product [Mus musculus] 244233 3454 0.01 0.056666667 2.502500341 Up 0.168133439 Cd163l1 CD163 molecule-like 1 K06545|1|0.0|814|clv:102095872|CD163 antigen GO:0016020//membrane - - gi|91064872|ref|NP_766497.3|/0/CD163 molecule-like 1 precursor [Mus musculus] 108809 1873 0.056666667 0.01 -2.502500341 Down 0.168133439 4933407E24Rik RIKEN cDNA 4933407E24 gene - - - - - 211223 2568 0.01 0.056666667 2.502500341 Up 0.168133439 Vmn2r15 "vomeronasal 2, receptor 15" K04613|1|0.0|1719|mmu:211223|vomeronasal 2 receptor - - - "gi|157277979|ref|NP_001098096.1|/0/vomeronasal 2, receptor 15 precursor [Mus musculus]" 69307 1015 0.01 0.056666667 2.502500341 Up 0.168133439 Pxt1 "peroxisomal, testis specific 1" - GO:0042579//microbody - - "gi|148690649|gb|EDL22596.1|/5.1414e-59/peroxisomal, testis specific 1, partial [Mus musculus]" 664793 832 0.01 0.056666667 2.502500341 Up 0.168133439 Zp4-ps "zona pellucida glycoprotein 4, pseudogene" K19926|1|4e-21|103|cmy:102930168|zona pellucida sperm-binding protein 1 - - - - 21682 2588.03 2.64 2.853333333 0.112110366 Up 0.168133439 Tec tec protein tyrosine kinase K07364|1|0.0|974|mmu:21682|tyrosine-protein kinase Tec [EC:2.7.10.2] GO:0043232;GO:0016020//membrane;GO:0043232;GO:0016020//membrane;GO:0043232;GO:0016020//membrane;GO:0043232;GO:0016020//membrane GO:0043169//cation binding;GO:0032550;GO:0008289//lipid binding;GO:0004713//protein tyrosine kinase activity;GO:0043169//cation binding;GO:0032550;GO:0008289//lipid binding;GO:0004713//protein tyrosine kinase activity;GO:0043169//cation binding;GO:0032550;GO:0008289//lipid binding;GO:0004713//protein tyrosine kinase activity;GO:0043169//cation binding;GO:0032550;GO:0008289//lipid binding;GO:0004713//protein tyrosine kinase activity GO:0030168//platelet activation;GO:0009888//tissue development;GO:0006464//cellular protein modification process;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0030168//platelet activation;GO:0009888//tissue development;GO:0006464//cellular protein modification process;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0030168//platelet activation;GO:0009888//tissue development;GO:0006464//cellular protein modification process;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0030168//platelet activation;GO:0009888//tissue development;GO:0006464//cellular protein modification process;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006796//phosphate-containing compound metabolic process gi|164698392|ref|NP_001106932.1|/0/tyrosine-protein kinase Tec isoform b [Mus musculus] 102639404 842 0.01 0.056666667 2.502500341 Up 0.168133439 Gm26839 "predicted gene, 26839" - - - - - 408190 1074 0.01 0.056666667 2.502500341 Up 0.168133439 Wfdc13 WAP four-disulfide core domain 13 - - GO:0004866//endopeptidase inhibitor activity GO:0051346//negative regulation of hydrolase activity gi|60592762|ref|NP_001012722.1|/2.80442e-26/WAP four-disulfide core domain protein 13 precursor [Mus musculus] 71586 5519 1.546666667 1.39 -0.154077422 Down 0.168086427 Ifih1 interferon induced with helicase C domain 1 K12647|1|0.0|1889|mmu:71586|interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0032550;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0042623//ATPase activity, coupled" GO:0006952//defense response;GO:0051707//response to other organism;GO:0006915//apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0032481//positive regulation of type I interferon production;GO:0002252;GO:0006952//defense response;GO:0051707//response to other organism;GO:0006915//apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0032481//positive regulation of type I interferon production;GO:0002252 gi|257096038|ref|NP_001157949.1|/0/interferon-induced helicase C domain-containing protein 1 isoform 2 [Mus musculus] 319266 3630 1.426666667 1.583333333 0.150316717 Up 0.168086427 A130010J15Rik RIKEN cDNA A130010J15 gene - - - - "gi|148681008|gb|EDL12955.1|/1.71445e-148/RIKEN cDNA A130010J15, isoform CRA_b, partial [Mus musculus]" 76863 1201 26.69333333 27.61 0.048711414 Up 0.168030012 Dcun1d5 "DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)" K17824|1|6e-124|446|mmu:76863|DCN1-like protein 4/5 - - - gi|23956220|ref|NP_084051.1|/5.02015e-123/DCN1-like protein 5 [Mus musculus] 11941 6922 0.213333333 0.136666667 -0.642447995 Down 0.167964196 Atp2b2 "ATPase, Ca++ transporting, plasma membrane 2" "K05850|1|0.0|2107|mmu:11941|Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]" GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0043025//neuronal cell body;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0043025//neuronal cell body GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0019829//cation-transporting ATPase activity;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0019829//cation-transporting ATPase activity GO:0050804//modulation of synaptic transmission;GO:0022037//metencephalon development;GO:0050954//sensory perception of mechanical stimulus;GO:0002093//auditory receptor cell morphogenesis;GO:0031214//biomineral tissue development;GO:0006874//cellular calcium ion homeostasis;GO:0007589//body fluid secretion;GO:0009154//purine ribonucleotide catabolic process;GO:0044708//single-organism behavior;GO:0021533//cell differentiation in hindbrain;GO:0050905//neuromuscular process;GO:0032535//regulation of cellular component size;GO:0006816//calcium ion transport;GO:0042430//indole-containing compound metabolic process;GO:0050804//modulation of synaptic transmission;GO:0022037//metencephalon development;GO:0050954//sensory perception of mechanical stimulus;GO:0002093//auditory receptor cell morphogenesis;GO:0031214//biomineral tissue development;GO:0006874//cellular calcium ion homeostasis;GO:0007589//body fluid secretion;GO:0009154//purine ribonucleotide catabolic process;GO:0044708//single-organism behavior;GO:0021533//cell differentiation in hindbrain;GO:0050905//neuromuscular process;GO:0032535//regulation of cellular component size;GO:0006816//calcium ion transport;GO:0042430//indole-containing compound metabolic process "gi|148667088|gb|EDK99504.1|/0/ATPase, Ca++ transporting, plasma membrane 2, isoform CRA_b, partial [Mus musculus]" 71489 3138 0.143333333 0.223333333 0.639824436 Up 0.167964196 Bcas3os1 "breast carcinoma amplified sequence 3, opposite strand 1" - - - - "gi|148683825|gb|EDL15772.1|/1.42568e-52/mCG145252, partial [Mus musculus]" 140709 2705 0.023333333 0.086666667 1.893084796 Up 0.167926586 Col26a1 "collagen, type XXVI, alpha 1" - GO:0044432;GO:0016020//membrane;GO:0005578//proteinaceous extracellular matrix - GO:0043062//extracellular structure organization;GO:0010810//regulation of cell-substrate adhesion "gi|148687358|gb|EDL19305.1|/0/EMI domain containing 2, isoform CRA_c, partial [Mus musculus]" 14468 2820 0.023333333 0.086666667 1.893084796 Up 0.167926586 Gbp2b guanylate binding protein 2b K17339|1|1e-17|94.7|crg:105327935|atlastin [EC:3.6.5.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0020003//symbiont-containing vacuole GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0032496//response to lipopolysaccharide;GO:0001562//response to protozoan;GO:0042742//defense response to bacterium;GO:0002252;GO:0034341//response to interferon-gamma;GO:0009154//purine ribonucleotide catabolic process;GO:0051702//interaction with symbiont;GO:0035456//response to interferon-beta gi|134031982|ref|NP_034389.2|/0/guanylate-binding protein 1 [Mus musculus] 14525 3298 0.023333333 0.086666667 1.893084796 Up 0.167926586 Gcsam "germinal center associated, signaling and motility" - GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0017022//myosin binding;GO:0017022//myosin binding GO:0002686//negative regulation of leukocyte migration;GO:0002686//negative regulation of leukocyte migration gi|226530838|ref|NP_032125.3|/3.67733e-91/germinal center-associated signaling and motility protein isoform 2 [Mus musculus] 13390 2794 0.023333333 0.083333333 1.836501268 Up 0.167926586 Dlx1 distal-less homeobox 1 K09314|1|1e-120|437|pon:100439534|homeobox protein DLX1/4/6 - - - - 20353 3823.74 7.25 6.883333333 -0.074873619 Down 0.167917184 Sema4c "sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C" K06521|1|0.0|1541|mmu:20353|semaphorin 4 GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0016477//cell migration;GO:0022037//metencephalon development;GO:0007166//cell surface receptor signaling pathway;GO:0032872//regulation of stress-activated MAPK cascade;GO:0030154//cell differentiation;GO:0016477//cell migration;GO:0022037//metencephalon development;GO:0007166//cell surface receptor signaling pathway;GO:0032872//regulation of stress-activated MAPK cascade;GO:0030154//cell differentiation;GO:0016477//cell migration;GO:0022037//metencephalon development;GO:0007166//cell surface receptor signaling pathway;GO:0032872//regulation of stress-activated MAPK cascade;GO:0030154//cell differentiation gi|568906005|ref|XP_006495867.1|/0/PREDICTED: semaphorin-4C isoform X3 [Mus musculus] 100756 2790 6.966666667 7.333333333 0.074000581 Up 0.167917184 Usp30 ubiquitin specific peptidase 30 K11851|1|0.0|924|mmu:100756|ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12] GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019941//modification-dependent protein catabolic process "gi|24047300|gb|AAH38606.1|/0/Usp30 protein, partial [Mus musculus]" 75255 830 7.103333333 7.473333333 0.073255685 Up 0.167917184 4930562F07Rik RIKEN cDNA 4930562F07 gene - - - - "gi|148707400|gb|EDL39347.1|/2.4002e-63/mCG146136, partial [Mus musculus]" 13853 1079 8.146666667 7.78 -0.066439724 Down 0.167917184 Epm2a "epilepsy, progressive myoclonic epilepsy, type 2 gene alpha" K14165|1|2e-175|617|mmu:13853|atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] - - - gi|116063575|ref|NP_034276.2|/1.81683e-174/laforin [Mus musculus] 70420 2184 6.996666667 7.37 0.074996859 Up 0.167917184 Arpin actin-related protein 2/3 complex inhibitor - - - - gi|47498088|ref|NP_081696.1|/1.83916e-117/arpin [Mus musculus] 277744 922 0.926666667 0.8 -0.212050477 Down 0.167832562 Gm694 predicted gene 694 - - - - gi|85701868|ref|NP_001028546.1|/6.86466e-89/uncharacterized protein C1orf64 homolog [Mus musculus] 71362 1016 0.916666667 0.79 -0.21454456 Down 0.167832562 5430440P10Rik RIKEN cDNA 5430440P10 gene - - - - - 72668 4387 0.933333333 0.806666667 -0.21041978 Down 0.167832562 Skida1 SKI/DACH domain containing 1 - - - - - 14426 5136 0.93 0.803333333 -0.211231976 Down 0.167832562 Galnt4 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 K00710|1|0.0|1170|mmu:14426|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0016740//transferase activity - gi|7657112|ref|NP_056552.1|/0/polypeptide N-acetylgalactosaminyltransferase 4 [Mus musculus] 233147 1980 0.973333333 0.843333333 -0.206830984 Down 0.167832562 Zfp939 zinc finger protein 939 K09228|1|0.0|1269|mmu:233147|KRAB domain-containing zinc finger protein - - - gi|339895832|ref|NP_001229950.1|/0/zinc finger protein 939 [Mus musculus] 22678 3084 0.846666667 0.976666667 0.206072168 Up 0.167832562 Zfp2 zinc finger protein 2 K09228|1|0.0|948|ngi:103749394|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|30425364|ref|NP_848542.1|/0/zinc finger protein 2 [Mus musculus] 240255 6299 0.816666667 0.943333333 0.208020304 Up 0.167832562 Ythdc2 YTH domain containing 2 K20099|1|0.0|2573|mmu:240255|ATP-dependent RNA helicase YTHDC2 [EC:3.6.4.13] - "GO:0032550;GO:0042623//ATPase activity, coupled" - gi|244793002|ref|NP_001156485.1|/0/probable ATP-dependent RNA helicase YTHDC2 [Mus musculus] 14793 1488 0.793333333 0.92 0.213706693 Up 0.167832562 Cdca3 cell division cycle associated 3 - GO:0005737//cytoplasm - GO:0032446//protein modification by small protein conjugation;GO:0000087//mitotic M phase "gi|148667354|gb|EDK99770.1|/1.36595e-147/cell division cycle associated 3, isoform CRA_b [Mus musculus]" 383295 2869 10.90333333 11.39666667 0.063842663 Up 0.167747941 Ypel5 yippee-like 5 (Drosophila) - - "GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor" GO:0044710 gi|852808141|ref|XP_012892223.1|/6.15127e-71/PREDICTED: protein yippee-like 5 [Dipodomys ordii] 20874 6960.15 12.29333333 12.78666667 0.056764065 Up 0.167747941 Slk STE20-like kinase K08836|1|0.0|1989|mmu:20874|STE20-like kinase [EC:2.7.11.1] GO:0044424;GO:0044424 GO:0042802//identical protein binding;GO:0004672//protein kinase activity;GO:0032550;GO:0042802//identical protein binding;GO:0004672//protein kinase activity;GO:0032550 GO:0006468//protein phosphorylation;GO:0012501//programmed cell death;GO:0006468//protein phosphorylation;GO:0012501//programmed cell death gi|28972093|dbj|BAC65500.1|/0/mKIAA0204 protein [Mus musculus] 277463 3926 12.55333333 12.06333333 -0.057441892 Down 0.167747941 Gpr107 G protein-coupled receptor 107 - GO:0031224//intrinsic component of membrane - - gi|254692915|ref|NP_848875.2|/0/protein GPR107 precursor [Mus musculus] 67288 1800.22 10.95333333 11.44666667 0.063557559 Up 0.167747941 Srek1ip1 splicing regulatory glutamine/lysine-rich protein 1interacting protein 1 - - GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0006396//RNA processing "gi|148686541|gb|EDL18488.1|/3.99928e-57/RIKEN cDNA 3110031B13, isoform CRA_a, partial [Mus musculus]" 229801 2225 0.086666667 0.026666667 -1.700439718 Down 0.167738538 Tram1l1 translocation associated membrane protein 1-like 1 K14010|1|2e-108|395|bta:281546|translocating chain-associated membrane protein 1 - - - - 93675 2248 0.026666667 0.083333333 1.64385619 Up 0.167738538 Clec2i "C-type lectin domain family 2, member i" K10072|1|2e-55|220|cge:100765032|C-type lectin domain family 2 member D GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0009986//cell surface GO:0005102//receptor binding;GO:0038023//signaling receptor activity GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0045953//negative regulation of natural killer cell mediated cytotoxicity;GO:0050851//antigen receptor-mediated signaling pathway;GO:0072657//protein localization to membrane;GO:0008064//regulation of actin polymerization or depolymerization;GO:0032663;GO:0001771//immunological synapse formation;GO:0042098//T cell proliferation gi|576067781|ref|NP_001276635.1|/9.22449e-142/C-type lectin domain family 2 member I isoform 1 [Mus musculus] 242939 2189 0.03 0.09 1.584962501 Up 0.167738538 Cpz carboxypeptidase Z K13022|1|0.0|1273|mmu:242939|carboxypeptidase Z [EC:3.4.17.-] GO:0031012//extracellular matrix GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding GO:0007166//cell surface receptor signaling pathway;GO:0051604//protein maturation gi|120407066|ref|NP_694747.2|/0/carboxypeptidase Z precursor [Mus musculus] 18106 3758 0.03 0.09 1.584962501 Up 0.167738538 Cd244 CD244 natural killer cell receptor 2B4 K06582|1|0.0|820|mmu:18106|natural killer cell receptor 2B4 - - - - 230863 3158 0.023333333 0.08 1.777607579 Up 0.167738538 Sh2d5 SH2 domain containing 5 "K20198|1|8e-11|72.4|chx:102190277|kinesin family member 17;K06236|2|5e-07|59.7|cjo:107325218|collagen, type I, alpha" - - - "gi|22477590|gb|AAH36961.1|/0/Sh2d5 protein, partial [Mus musculus]" 331487 1112 0.14 0.216666667 0.63005039 Up 0.167719734 Uprt uracil phosphoribosyltransferase K00761|1|6e-178|625|mmu:331487|uracil phosphoribosyltransferase [EC:2.4.2.9] GO:0043231//intracellular membrane-bounded organelle GO:0016740//transferase activity GO:0044703;GO:0009174;GO:0043434//response to peptide hormone;GO:0007589//body fluid secretion gi|124487135|ref|NP_001074658.1|/5.36834e-177/uracil phosphoribosyltransferase homolog [Mus musculus] 226414 2249 24.18333333 23.29666667 -0.053889568 Down 0.167569296 Dars aspartyl-tRNA synthetase K01876|1|0.0|1001|mmu:226414|aspartyl-tRNA synthetase [EC:6.1.1.12] GO:0043234//protein complex;GO:0044424;GO:0043234//protein complex;GO:0044424 GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation gi|148707802|gb|EDL39749.1|/0/aspartyl-tRNA synthetase [Mus musculus] 218335 2378 27.25666667 28.14333333 0.046184074 Up 0.167569296 Clptm1l CLPTM1-like - GO:0031224//intrinsic component of membrane - GO:0012501//programmed cell death gi|326937503|ref|NP_666159.2|/0/cleft lip and palate transmembrane protein 1-like protein [Mus musculus] 230657 2409 23.10333333 23.99666667 0.054733 Up 0.167569296 Tmem69 transmembrane protein 69 "K10591|1|7e-07|58.9|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26];K13168|2|1e-06|58.2|phu:Phum_PHUM606410|splicing factor, arginine/serine-rich 16" - - - gi|161621250|ref|NP_808338.2|/1.38374e-129/transmembrane protein 69 [Mus musculus] 218977 2966 0.37 0.276666667 -0.419376435 Down 0.167531686 Dlgap5 "discs, large (Drosophila) homolog-associated protein 5" K16804|1|0.0|1496|mmu:218977|disks large-associated protein 5 GO:0043231//intracellular membrane-bounded organelle;GO:0000922//spindle pole GO:0016791//phosphatase activity GO:0000278//mitotic cell cycle;GO:0007154//cell communication "gi|148688799|gb|EDL20746.1|/0/discs, large homolog 7 (Drosophila), isoform CRA_a, partial [Mus musculus]" 100568458 2999 0.373333333 0.28 -0.415037499 Down 0.167531686 Gm38431 "predicted gene, 38431" "K11219|1|5e-74|282|fch:102058589|non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2];K02516|2|7e-14|82.4|tsp:Tsp_08085|type II protein arginine methyltransferase [EC:2.1.1.320];K13219|3|6e-11|72.8|ame:726178|splicing factor, proline- and glutamine-rich;K13214|5|6e-10|69.3|xla:380427|non-POU domain-containing octamer-binding protein" - - - - 211798 3152 0.466666667 0.37 -0.334867151 Down 0.167531686 Mfsd9 major facilitator superfamily domain containing 9 "K08214|1|4e-16|90.1|hmg:100210882|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 18" GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763 gi|27369688|ref|NP_766087.1|/0/major facilitator superfamily domain-containing protein 9 [Mus musculus] 11688 3273 0.486666667 0.386666667 -0.331843564 Down 0.167531686 Alox8 arachidonate 8-lipoxygenase K08022|1|0.0|1356|mmu:11688|arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-] GO:0044424 "GO:0046914//transition metal ion binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" GO:0051726//regulation of cell cycle;GO:0040007//growth;GO:0006690//icosanoid metabolic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0008283//cell proliferation "gi|148678536|gb|EDL10483.1|/0/arachidonate 8-lipoxygenase, partial [Mus musculus]" 78575 4069 0.253333333 0.34 0.424497829 Up 0.167531686 B430319G15Rik RIKEN cDNA B430319G15 gene "K13645|1|8e-13|79.3|mmu:26432|procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 [EC:1.14.11.4];K02924|2|4e-12|77.0|ocu:100343258|large subunit ribosomal protein L39e" - - - "gi|148688976|gb|EDL20923.1|/7.33251e-12/procollagen lysine, 2-oxoglutarate 5-dioxygenase 2, isoform CRA_b [Mus musculus]" 73873 1953 0.28 0.373333333 0.415037499 Up 0.167531686 Fam161a "family with sequence similarity 161, member A" K16772|1|0.0|728|mmu:73873|protein FAM161A GO:0031513//nonmotile primary cilium - GO:0010927 "gi|148675930|gb|EDL07877.1|/0/RIKEN cDNA 4930430E16, isoform CRA_a, partial [Mus musculus]" 16497 2851 0.343333333 0.256666667 -0.419713986 Down 0.167531686 Kcnab1 "potassium voltage-gated channel, shaker-related subfamily, beta member 1" "K04882|1|0.0|801|mmu:16497|potassium voltage-gated channel Shaker-related subfamily A, beta member 1" GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424 GO:0005488//binding;GO:0016247//channel regulator activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0016247//channel regulator activity;GO:0005267//potassium channel activity GO:0007267//cell-cell signaling;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0007267//cell-cell signaling;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|148747467|ref|NP_034727.3|/0/voltage-gated potassium channel subunit beta-1 isoform 1 [Mus musculus] 67849 1906 0.36 0.27 -0.415037499 Down 0.167531686 Cdca5 cell division cycle associated 5 K17390|1|6e-117|424|mmu:67849|sororin GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0000793//condensed chromosome;GO:0016020//membrane GO:0005488//binding GO:0006281//DNA repair;GO:0000070//mitotic sister chromatid segregation;GO:0007063//regulation of sister chromatid cohesion gi|13385902|ref|NP_080686.1|/4.99695e-116/sororin [Mus musculus] 330171 3095.46 26.91666667 26.03666667 -0.047954999 Down 0.167484674 Kctd10 potassium channel tetramerisation domain containing 10 K15074|1|8e-162|573|ssc:100519625|BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein GO:0031461//cullin-RING ubiquitin ligase complex;GO:0035869//ciliary transition zone;GO:0035869//ciliary transition zone - GO:0006511//ubiquitin-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation;GO:0051259//protein oligomerization;GO:0051259//protein oligomerization gi|927205201|ref|XP_013838429.1|/2.83259e-162/PREDICTED: BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 isoform X2 [Sus scrofa] 66827 1469 26.43666667 27.31333333 0.04706511 Up 0.167484674 Ttc1 tetratricopeptide repeat domain 1 K19870|1|1e-17|94.0|pss:102461397|sperm-associated antigen 1 GO:0044439 - - gi|20452462|ref|NP_598556.1|/2.43956e-149/tetratricopeptide repeat protein 1 [Mus musculus] 19090 12674 0.53 0.64 0.272079545 Up 0.167475272 Prkdc "protein kinase, DNA activated, catalytic polypeptide" K06642|1|0.0|7992|mmu:19090|DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1] GO:0044428//nuclear part;GO:0043234//protein complex GO:0032550;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0004674//protein serine/threonine kinase activity GO:0032868//response to insulin;GO:0000726;GO:0007417//central nervous system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0003006//developmental process involved in reproduction;GO:0030183//B cell differentiation;GO:0006915//apoptotic process;GO:0006468//protein phosphorylation;GO:0002681;GO:0002320//lymphoid progenitor cell differentiation;GO:0009952//anterior/posterior pattern specification;GO:0010212//response to ionizing radiation gi|124517706|ref|NP_035289.2|/0/DNA-dependent protein kinase catalytic subunit [Mus musculus] 93840 5714 0.65 0.54 -0.267480311 Down 0.167475272 Vangl2 "vang-like 2 (van gogh, Drosophila)" K04510|1|0.0|734|pale:102882434|vang-like GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0044459 GO:0005488//binding "GO:0014020;GO:0030010//establishment of cell polarity;GO:0014022;GO:0042384//cilium assembly;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0048104//establishment of body hair or bristle planar orientation;GO:0043406//positive regulation of MAP kinase activity;GO:0035051//cardiocyte differentiation;GO:0001822//kidney development;GO:0003401//axis elongation;GO:0001837//epithelial to mesenchymal transition;GO:0008544//epidermis development;GO:0003151//outflow tract morphogenesis;GO:0007265//Ras protein signal transduction;GO:0048666//neuron development;GO:0060026//convergent extension;GO:0003143//embryonic heart tube morphogenesis;GO:0003002//regionalization;GO:0008105//asymmetric protein localization;GO:0060448//dichotomous subdivision of terminal units involved in lung branching;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0030036//actin cytoskeleton organization;GO:0042249//establishment of planar polarity of embryonic epithelium;GO:0019827//stem cell population maintenance;GO:0017145//stem cell division;GO:0009611//response to wounding" gi|37360286|dbj|BAC98121.1|/0/mKIAA1215 protein [Mus musculus] 192196 4115.87 24.68666667 25.55666667 0.04996763 Up 0.167353041 Luc7l2 LUC7-like 2 (S. cerevisiae) K13212|1|8e-115|417|rno:312251|RNA-binding protein Luc7-like 2 - GO:0005515//protein binding;GO:0043169//cation binding;GO:0005515//protein binding;GO:0043169//cation binding;GO:0005515//protein binding;GO:0043169//cation binding - gi|157822829|ref|NP_001101323.1|/7.20616e-114/LUC7-like 2 pre-mRNA splicing factor [Rattus norvegicus] 109154 5970 23.31 22.44 -0.054876329 Down 0.167353041 Mlec malectin - GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0044238//primary metabolic process gi|37359796|dbj|BAC97876.1|/4.20403e-136/mKIAA0152 protein [Mus musculus] 654424 4451 0.723333333 0.846666667 0.227133454 Up 0.167306029 Mccc1os "methylcrotonoyl-Coenzyme A carboxylase 1 (alpha), opposite strand" - - - - gi|26327927|dbj|BAC27704.1|/4.34529e-82/unnamed protein product [Mus musculus] 67770 2109 0.706666667 0.826666667 0.226275856 Up 0.167306029 Caap1 caspase activity and apoptosis inhibitor 1 K14018|1|7e-60|234|mgp:100541843|phospholipase A-2-activating protein - - - gi|268837283|ref|NP_080644.2|/2.14563e-139/caspase activity and apoptosis inhibitor 1 [Mus musculus] 16172 3970 2.153333333 2.346666667 0.124041264 Up 0.167296626 Il17ra interleukin 17 receptor A K05164|1|0.0|1596|mmu:16172|interleukin 17 receptor GO:0031224//intrinsic component of membrane - GO:0001775//cell activation;GO:0034097//response to cytokine;GO:0001819//positive regulation of cytokine production gi|6680411|ref|NP_032385.1|/0/interleukin-17 receptor A precursor [Mus musculus] 215512 2334 2.103333333 2.29 0.122670094 Up 0.167296626 Fam117a "family with sequence similarity 117, member A" "K15275|1|1e-102|376|apla:101803377|solute carrier family 35 (UDP-galactose transporter), member B1" - - - gi|262263417|ref|NP_766131.2|/0/protein FAM117A [Mus musculus] 209086 5344 2.416666667 2.23 -0.115974784 Down 0.167296626 Samd9l sterile alpha motif domain containing 9-like - - - - gi|226958514|ref|NP_034286.2|/0/sterile alpha motif domain-containing protein 9-like [Mus musculus] 24018 4157 2.26 2.073333333 -0.124370693 Down 0.167296626 Rngtt RNA guanylyltransferase and 5'-phosphatase K13917|1|0.0|1146|mmu:24018|mRNA-capping enzyme [EC:2.7.7.50 3.6.1.-] - - - - 53418 2432 2.226666667 2.413333333 0.116141595 Up 0.167296626 B4galt2 "UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2" "K07967|1|0.0|401|mmu:53418|beta-1,4-galactosyltransferase 2 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]" GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0035250//UDP-galactosyltransferase activity;GO:0043169//cation binding;GO:0035250//UDP-galactosyltransferase activity;GO:0043169//cation binding;GO:0035250//UDP-galactosyltransferase activity GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process "gi|926689000|ref|XP_013818369.1|/0/PREDICTED: beta-1,4-galactosyltransferase 2, partial [Capra hircus]" 17168 2946.54 10.70333333 11.18333333 0.063290101 Up 0.167249615 Nprl3 nitrogen permease regulator-like 3 K20406|1|0.0|1038|mmu:17168|nitrogen permease regulator 3-like protein - - - "gi|148691813|gb|EDL23760.1|/0/alpha globin regulatory element containing gene, isoform CRA_a, partial [Mus musculus]" 20024 3321 10.35333333 10.83 0.064937914 Up 0.167249615 Sub1 SUB1 homolog (S. cerevisiae) - GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0003712//transcription cofactor activity;GO:0043566//structure-specific DNA binding GO:0006366//transcription from RNA polymerase II promoter gi|74226891|dbj|BAE27090.1|/1.5799e-41/unnamed protein product [Mus musculus] 26385 2814.55 11.06666667 11.54333333 0.060839146 Up 0.167249615 Grk6 G protein-coupled receptor kinase 6 K08291|1|0.0|602|mmu:26385|G protein-coupled receptor kinase [EC:2.7.11.16] GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity GO:0010359//regulation of anion channel activity;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0010359//regulation of anion channel activity;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0010359//regulation of anion channel activity;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0010359//regulation of anion channel activity;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0010359//regulation of anion channel activity;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0010359//regulation of anion channel activity;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0010359//regulation of anion channel activity;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway gi|163310714|ref|NP_001106182.1|/0/G protein-coupled receptor kinase 6 isoform c [Mus musculus] 21899 2600 0.253333333 0.17 -0.575502171 Down 0.167212005 Tlr6 toll-like receptor 6 K10169|1|0.0|1635|mmu:21899|toll-like receptor 6 GO:0031982//vesicle;GO:0031224//intrinsic component of membrane;GO:0043235//receptor complex GO:0071723//lipopeptide binding;GO:0038023//signaling receptor activity;GO:0046983//protein dimerization activity GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;GO:0052166;GO:0071221//cellular response to bacterial lipopeptide;GO:0006807//nitrogen compound metabolic process;GO:0001774//microglial cell activation;GO:0002224//toll-like receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043406//positive regulation of MAP kinase activity;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0070340;GO:0042090 gi|157057101|ref|NP_035734.3|/0/toll-like receptor 6 [Mus musculus] 100043416 2857 0.166666667 0.25 0.584962501 Up 0.167212005 Gm4425 KRAB-domain protein pseudogene K09228|1|5e-23|112|mmu:105245545|KRAB domain-containing zinc finger protein - - - - 320312 1954 0.153333333 0.23 0.584962501 Up 0.167212005 A430035B10Rik RIKEN cDNA A430035B10 gene - - - - gi|148681987|gb|EDL13934.1|/1.76263e-23/mCG147468 [Mus musculus] 320407 3913 0.243333333 0.16 -0.604862058 Down 0.167212005 Klri2 killer cell lectin-like receptor family I member 2 K06541|1|4e-08|63.9|lve:103074952|killer cell lectin-like receptor subfamily C - - - gi|282721126|ref|NP_796129.2|/9.7915e-131/killer cell lectin-like receptor family I member 2 [Mus musculus] 105450 3935 23.68 22.82333333 -0.053159569 Down 0.1671932 Mmrn2 multimerin 2 K16464|1|1e-06|58.9|gja:107107853|centrosomal protein CEP250;K10352|5|6e-06|56.6|ola:101165692|myosin heavy chain GO:0005578//proteinaceous extracellular matrix - GO:0009968//negative regulation of signal transduction;GO:0016525//negative regulation of angiogenesis gi|122937370|ref|NP_694767.3|/0/multimerin-2 precursor [Mus musculus] 67898 1551 23.29666667 24.16 0.052496909 Up 0.1671932 Pef1 penta-EF hand domain containing 1 "K08585|1|6e-16|88.2|nvi:100119123|calpain, invertebrate [EC:3.4.22.-];K08580|2|8e-16|87.8|myd:102773208|calpain-11 [EC:3.4.22.-];K01367|3|1e-15|87.4|mze:101468863|calpain-1 [EC:3.4.22.52];K08584|4|1e-15|87.4|umr:103673787|calpain, small subunit 2" GO:0044424 GO:0046872//metal ion binding;GO:0046983//protein dimerization activity GO:0010038//response to metal ion "gi|119628003|gb|EAX07598.1|/3.84726e-102/penta-EF-hand domain containing 1, isoform CRA_a [Homo sapiens]" 100041515 1654 0.393333333 0.49 0.317029295 Up 0.167155591 Gm3383 predicted gene 3383 "K03844|1|1e-18|97.1|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - gi|755546848|ref|XP_011243028.1|/3.40466e-96/PREDICTED: predicted gene 3468 isoform X1 [Mus musculus] 93876 3533 0.563333333 0.673333333 0.257332046 Up 0.167099176 Pcdhb5 protocadherin beta 5 K16494|1|0.0|1465|mmu:93876|protocadherin beta - - - - 12611 4718 4.083333333 4.336666667 0.086839213 Up 0.167099176 Cebpg "CCAAT/enhancer binding protein (C/EBP), gamma" "K10049|1|3e-58|230|cge:100770190|CCAAT/enhancer binding protein (C/EBP), gamma" GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0043566//structure-specific DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0034728//nucleosome organization;GO:0042095//interferon-gamma biosynthetic process;GO:0044092//negative regulation of molecular function;GO:0030218//erythrocyte differentiation;GO:0016568//chromatin modification;GO:0001909//leukocyte mediated cytotoxicity;GO:0006281//DNA repair gi|672035601|ref|XP_008757334.1|/2.4586e-83/PREDICTED: CCAAT/enhancer-binding protein gamma isoform X1 [Rattus norvegicus] 66960 2333 3.98 3.73 -0.0935928 Down 0.167099176 Fam188a "family with sequence similarity 188, member A" K08742|1|2e-09|67.0|cge:100773133|E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27] GO:0005635//nuclear envelope;GO:0031981//nuclear lumen GO:0046872//metal ion binding GO:0012501//programmed cell death gi|15277329|ref|NP_077147.2|/0/protein FAM188A [Mus musculus] 192285 6333.67 4.13 3.88 -0.090085129 Down 0.167099176 Phf21a PHD finger protein 21A K11643|1|7e-15|87.0|cqu:CpipJ_CPIJ004665|chromodomain-helicase-DNA-binding protein 4 [EC:3.6.4.12];K10603|3|3e-14|84.7|mze:101467837|autoimmune regulator - - - gi|157841178|ref|NP_001103161.1|/0/PHD finger protein 21A isoform 3 [Mus musculus] 72194 8607 4.383333333 4.13 -0.085886612 Down 0.167099176 Fbxl20 F-box and leucine-rich repeat protein 20 K10268|1|0.0|887|mmu:72194|F-box and leucine-rich repeat protein 2/20 GO:0044424 - - gi|60359876|dbj|BAD90157.1|/0/mKIAA4147 protein [Mus musculus] 68533 1054 4.236666667 3.983333333 -0.088953412 Down 0.167099176 Mphosph6 M phase phosphoprotein 6 "K12593|1|6e-74|280|mmu:68533|M-phase phosphoprotein 6, animal type" GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0006364//rRNA processing gi|21312048|ref|NP_081034.1|/5.06957e-73/M-phase phosphoprotein 6 [Mus musculus] 11881 3989 4.003333333 4.253333333 0.087392178 Up 0.167099176 Arsb arylsulfatase B K01135|1|0.0|1060|mmu:11881|arylsulfatase B [EC:3.1.6.12] GO:0000323//lytic vacuole;GO:0005783//endoplasmic reticulum GO:0008484//sulfuric ester hydrolase activity;GO:0043169//cation binding GO:0048545//response to steroid hormone;GO:0031667//response to nutrient levels;GO:0009628//response to abiotic stimulus;GO:0007399//nervous system development;GO:0044248 "gi|148668607|gb|EDL00926.1|/0/arylsulfatase B, partial [Mus musculus]" 66086 1438 25.88333333 25.03333333 -0.048173017 Down 0.167089774 Fopnl Fgfr1op N-terminal like K16535|1|5e-94|347|mmu:66086|lisH domain-containing protein FOPNL GO:0005929//cilium;GO:0005813//centrosome - GO:0000226//microtubule cytoskeleton organization;GO:0010927 gi|21313614|ref|NP_079621.1|/4.09374e-93/lisH domain-containing protein FOPNL [Mus musculus] 56441 2020 22.71666667 23.56666667 0.052996558 Up 0.167089774 Nat6 N-acetyltransferase 6 "K00463|1|6e-16|88.6|tsp:Tsp_04838|indoleamine 2,3-dioxygenase [EC:1.13.11.52];K09187|2|8e-06|55.1|cfr:102515223|histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43]" GO:0000323//lytic vacuole;GO:0031982//vesicle GO:0015929//hexosaminidase activity;GO:0016407//acetyltransferase activity;GO:0004872//receptor activity GO:0006952//defense response;GO:0009636//response to toxic substance;GO:0051707//response to other organism;GO:0010224//response to UV-B;GO:0001501//skeletal system development;GO:0034612//response to tumor necrosis factor;GO:0070555//response to interleukin-1;GO:0006027//glycosaminoglycan catabolic process gi|9789957|ref|NP_062724.1|/6.3227e-133/N-acetyltransferase 6 [Mus musculus] 234407 3189 22.20333333 23.05666667 0.054407675 Up 0.167089774 Colgalt1 collagen beta(1-O)galactosyltransferase 1 "K11703|1|0.0|1115|mmu:234407|collagen beta-1,O-galactosyltransferase [EC:2.4.1.50]" GO:0044432 GO:0035250//UDP-galactosyltransferase activity GO:0043062//extracellular structure organization;GO:0008610//lipid biosynthetic process gi|170784829|ref|NP_666323.2|/0/procollagen galactosyltransferase 1 precursor [Mus musculus] 53382 2558 23.84 24.69 0.050542601 Up 0.167089774 Txnl1 thioredoxin-like 1 K03671|1|1e-45|187|isc:IscW_ISCW001465|thioredoxin 1 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0015036//disulfide oxidoreductase activity GO:0051234//establishment of localization;GO:0019725//cellular homeostasis;GO:0018904;GO:0006091//generation of precursor metabolites and energy gi|31543902|ref|NP_058072.2|/3.39024e-166/thioredoxin-like protein 1 [Mus musculus] 50766 5995 7.553333333 7.193333333 -0.070452996 Down 0.166958141 Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) "K19721|1|2e-28|132|mze:106675429|collagen, type V/XI/XXIV/XXVII, alpha" GO:0031224//intrinsic component of membrane GO:0019838//growth factor binding;GO:0004866//endopeptidase inhibitor activity - gi|71895029|ref|NP_056615.1|/0/cysteine-rich motor neuron 1 protein precursor [Mus musculus] 69051 1615 6.893333333 7.256666667 0.074105222 Up 0.166958141 Pycr2 "pyrroline-5-carboxylate reductase family, member 2" K00286|1|5e-176|620|mmu:69051|pyrroline-5-carboxylate reductase [EC:1.5.1.2] GO:0044424 "GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0036094//small molecule binding" GO:0006561//proline biosynthetic process gi|19526878|ref|NP_598466.1|/3.84316e-175/pyrroline-5-carboxylate reductase 2 [Mus musculus] 100316932 122 6.95 7.313333333 0.073516142 Up 0.166958141 Snora28 "small nucleolar RNA, H/ACA box 28" - - - - - 319748 3698.94 7.486666667 7.126666667 -0.071096075 Down 0.166958141 Zfp865 zinc finger protein 865 K09228|1|2e-63|247|fab:107603334|KRAB domain-containing zinc finger protein - GO:0005488//binding - gi|75677466|ref|NP_001028555.1|/0/zinc finger protein 865 isoform 1 [Mus musculus] 252875 3724 4.746666667 5.033333333 0.084599403 Up 0.166854714 Mios "missing oocyte, meiosis regulator, homolog (Drosophila)" K20407|1|0.0|1808|mmu:252875|WD repeat-containing protein mio - - - "gi|148681991|gb|EDL13938.1|/0/cDNA sequence BC020002, isoform CRA_b, partial [Mus musculus]" 67487 3724 5.703333333 5.413333333 -0.075288127 Down 0.166854714 Dhx40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 K18711|1|0.0|1569|mmu:67487|ATP-dependent RNA helicase DHX40 [EC:3.6.4.13] - "GO:0032550;GO:0042623//ATPase activity, coupled" - gi|144926009|ref|NP_080467.3|/0/probable ATP-dependent RNA helicase DHX40 [Mus musculus] 69903 3169 21.56333333 22.39666667 0.054703818 Up 0.166788898 Rasip1 Ras interacting protein 1 K14376|1|1e-45|187|myb:102258567|poly(A) polymerase [EC:2.7.7.19];K05702|5|2e-06|57.8|nve:NEMVE_v1g174672|afadin - - - - 67609 1331 23.98333333 24.81333333 0.049083368 Up 0.166788898 4930453N24Rik RIKEN cDNA 4930453N24 gene - - - GO:0012501//programmed cell death gi|148665825|gb|EDK98241.1|/0/mCG127693 [Mus musculus] 67988 4611 3.103333333 3.323333333 0.098812337 Up 0.166732483 Tmx3 thioredoxin-related transmembrane protein 3 K09585|1|0.0|843|rno:682967|thioredoxin domain-containing protein 10 [EC:5.3.4.1] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups;GO:0015036//disulfide oxidoreductase activity" GO:0044267//cellular protein metabolic process;GO:0019725//cellular homeostasis;GO:0018904 gi|37360566|dbj|BAC98261.1|/0/mKIAA1830 protein [Mus musculus] 66455 1781 3.13 3.353333333 0.099433242 Up 0.166732483 Cnpy4 canopy FGF signaling regulator 4 - - - - - 18760 3778 3.23 3.013333333 -0.100173893 Down 0.166732483 Prkd1 protein kinase D1 K06070|1|0.0|1712|mmu:18760|protein kinase D [EC:2.7.11.13] - GO:0032550;GO:0008289//lipid binding;GO:0043169//cation binding - gi|153945802|ref|NP_032884.2|/0/serine/threonine-protein kinase D1 [Mus musculus] 13350 1776 10.36666667 10.84 0.064412677 Up 0.166694874 Dgat1 diacylglycerol O-acyltransferase 1 K11155|1|0.0|930|mmu:13350|diacylglycerol O-acyltransferase 1 [EC:2.3.1.20 2.3.1.75 2.3.1.76] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0008289//lipid binding;GO:0016411//acylglycerol O-acyltransferase activity GO:0055081//anion homeostasis;GO:0006641//triglyceride metabolic process;GO:0035337;GO:0006650//glycerophospholipid metabolic process;GO:0010876//lipid localization;GO:0030072//peptide hormone secretion;GO:0034377//plasma lipoprotein particle assembly "gi|148697628|gb|EDL29575.1|/0/diacylglycerol O-acyltransferase 1, isoform CRA_a, partial [Mus musculus]" 28193 5473 12.24666667 11.77666667 -0.056457877 Down 0.166694874 Reep3 receptor accessory protein 3 K17338|1|2e-131|453|mmu:28193|receptor expression-enhancing protein 1/2/3/4 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|30519927|ref|NP_848721.1|/1.90374e-135/receptor expression-enhancing protein 3 isoform 2 [Mus musculus] 26431 5027 11.36333333 11.83666667 0.058876761 Up 0.166694874 Git2 G protein-coupled receptor kinase-interactor 2 K12487|1|0.0|1334|mmu:26431|G protein-coupled receptor kinase interactor 2 - - - - 24047 720 1.206666667 1.066666667 -0.177917792 Down 0.166610252 Ccl19 chemokine (C-C motif) ligand 19 K05512|1|9e-58|225|mmu:24047|C-C motif chemokine 19 GO:0009986//cell surface GO:0005125//cytokine activity;GO:0048020//CCR chemokine receptor binding GO:0001934//positive regulation of protein phosphorylation;GO:0002407//dendritic cell chemotaxis;GO:0043066//negative regulation of apoptotic process;GO:0051283//negative regulation of sequestering of calcium ion;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0000302//response to reactive oxygen species;GO:0007254//JNK cascade;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0034694//response to prostaglandin;GO:0043410//positive regulation of MAPK cascade;GO:0043551//regulation of phosphatidylinositol 3-kinase activity "gi|755507561|ref|XP_006538477.2|/3.2507e-81/PREDICTED: C-C motif chemokine 19-like, partial [Mus musculus]" 240665 3819 1.206666667 1.063333333 -0.182433273 Down 0.166610252 Ccnj cyclin J K06627|1|5e-07|60.1|hro:HELRODRAFT_95727|cyclin A;K13983|2|3e-06|57.4|dpe:Dper_GL13251|putative helicase MOV10L1 [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle - - gi|27370262|ref|NP_766427.1|/0/cyclin-J [Mus musculus] 16997 6620 1.07 1.21 0.177396251 Up 0.166610252 Ltbp2 latent transforming growth factor beta binding protein 2 K08023|1|0.0|3749|mmu:16997|latent transforming growth factor beta binding protein 2/3/4 GO:0044421;GO:0031988//membrane-bounded vesicle GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway gi|158341636|ref|NP_038617.3|/0/latent-transforming growth factor beta-binding protein 2 [Mus musculus] 21331 1755 1.42 1.27 -0.161062433 Down 0.166544436 T2 brachyury 2 - - - GO:0007399//nervous system development gi|240255423|ref|NP_001155304.1|/0/brachyury 2 [Mus musculus] 723966 95 1.253333333 1.403333333 0.163087571 Up 0.166544436 Mirlet7c-2 microRNA let7c-2 - - - - - 104111 4524.51 1.363333333 1.216666667 -0.164204379 Down 0.166544436 Adcy3 adenylate cyclase 3 K08043|1|0.0|1970|mmu:104111|adenylate cyclase 3 [EC:4.6.1.1] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0032550;GO:0005515//protein binding;GO:0004016//adenylate cyclase activity;GO:0043169//cation binding;GO:0032550;GO:0005515//protein binding;GO:0004016//adenylate cyclase activity;GO:0043169//cation binding;GO:0032550;GO:0005515//protein binding;GO:0004016//adenylate cyclase activity;GO:0043169//cation binding GO:0045762//positive regulation of adenylate cyclase activity;GO:0007126//meiotic nuclear division;GO:0007165//signal transduction;GO:0007606//sensory perception of chemical stimulus;GO:0045762//positive regulation of adenylate cyclase activity;GO:0007126//meiotic nuclear division;GO:0007165//signal transduction;GO:0007606//sensory perception of chemical stimulus;GO:0045762//positive regulation of adenylate cyclase activity;GO:0007126//meiotic nuclear division;GO:0007165//signal transduction;GO:0007606//sensory perception of chemical stimulus gi|28972253|dbj|BAC65580.1|/0/mKIAA0511 protein [Mus musculus] 71409 5851 1.383333333 1.236666667 -0.16169215 Down 0.166544436 Fmnl2 formin-like 2 K04512|1|1e-36|159|dre:557451|dishevelled associated activator of morphogenesis - - - gi|124378048|ref|NP_765997.2|/0/formin-like protein 2 [Mus musculus] 69942 1246 1.28 1.43 0.159871337 Up 0.166544436 Rnf113a1 ring finger protein 113A1 K13127|1|0.0|636|mmu:69942|RING finger protein 113A - GO:0046914//transition metal ion binding - gi|23943840|ref|NP_705723.1|/2.76227e-180/RING finger protein 113A [Mus musculus] 20361 3290 25.96 25.15 -0.045731983 Down 0.166441009 Sema7a "sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A" K06529|1|0.0|1278|mmu:20361|semaphorin 7 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0005102//receptor binding GO:0048731//system development;GO:0030307//positive regulation of cell growth;GO:0007166//cell surface receptor signaling pathway;GO:0010934//macrophage cytokine production;GO:0048869//cellular developmental process;GO:0006954//inflammatory response;GO:0043410//positive regulation of MAPK cascade gi|6755466|ref|NP_035482.1|/0/semaphorin-7A precursor [Mus musculus] 21946 681 1.04 0.906666667 -0.197939378 Down 0.166234157 Pglyrp1 peptidoglycan recognition protein 1 K01446|1|1e-91|337|mmu:21946|N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] GO:0044424;GO:0044421 "GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0008329//signaling pattern recognition receptor activity;GO:0005539//glycosaminoglycan binding" GO:0012501//programmed cell death;GO:0001818//negative regulation of cytokine production;GO:0044116;GO:0042742//defense response to bacterium;GO:0042749//regulation of circadian sleep/wake cycle;GO:0002325;GO:0009581;GO:0000270//peptidoglycan metabolic process gi|6679293|ref|NP_033428.1|/9.00751e-91/peptidoglycan recognition protein 1 precursor [Mus musculus] 105837 3164 0.88 1.013333333 0.203533394 Up 0.166234157 Mtbp "Mdm2, transformed 3T3 cell double minute p53 binding protein" - - - GO:0000082//G1/S transition of mitotic cell cycle;GO:0008283//cell proliferation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0008283//cell proliferation gi|269914093|ref|NP_001161722.1|/0/mdm2-binding protein isoform 2 [Mus musculus] 76179 10198 0.893333333 1.023333333 0.196005655 Up 0.166234157 Usp31 ubiquitin specific peptidase 31 K11852|1|0.0|1986|mmu:76179|ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12] - - - gi|226443061|ref|NP_001028345.1|/0/ubiquitin carboxyl-terminal hydrolase 31 [Mus musculus] 108000 11130 1.026666667 0.896666667 -0.195324178 Down 0.166234157 Cenpf centromere protein F K11499|1|0.0|5131|mmu:108000|centromere protein F - - - gi|189458891|ref|NP_001074832.2|/0/centromere protein F [Mus musculus] 104457 829.94 23.80666667 24.60333333 0.047488156 Up 0.16620595 0610010K14Rik RIKEN cDNA 0610010K14 gene - GO:0044665//MLL1/2 complex;GO:0031010//ISWI-type complex;GO:0044665//MLL1/2 complex;GO:0031010//ISWI-type complex;GO:0044665//MLL1/2 complex;GO:0031010//ISWI-type complex;GO:0044665//MLL1/2 complex;GO:0031010//ISWI-type complex;GO:0044665//MLL1/2 complex;GO:0031010//ISWI-type complex;GO:0044665//MLL1/2 complex;GO:0031010//ISWI-type complex GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0005488//binding;GO:0003676//nucleic acid binding GO:0006325//chromatin organization;GO:0006325//chromatin organization;GO:0006325//chromatin organization;GO:0006325//chromatin organization;GO:0006325//chromatin organization gi|21389318|ref|NP_081033.1|/6.08601e-53/chromatin complexes subunit BAP18 isoform 4 [Mus musculus] 66212 552 10.56 10.1 -0.064254542 Down 0.166083719 Sec61b Sec61 beta subunit K09481|1|3e-30|133|mmu:66212|protein transport protein SEC61 subunit beta GO:0031224//intrinsic component of membrane;GO:0030867//rough endoplasmic reticulum membrane GO:0008320//protein transmembrane transporter activity;GO:0043021//ribonucleoprotein complex binding;GO:0019838//growth factor binding GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006606//protein import into nucleus;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0006613//cotranslational protein targeting to membrane;GO:0010467//gene expression "gi|148668529|gb|EDL00848.1|/2.0675e-68/mCG114989, partial [Mus musculus]" 234664 1808 11.03 10.57 -0.061457414 Down 0.166083719 Nae1 NEDD8 activating enzyme E1 subunit 1 K04532|1|0.0|1070|mmu:234664|amyloid beta precursor protein binding protein 1 GO:0016020//membrane GO:0008641//small protein activating enzyme activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0046983//protein dimerization activity;GO:0036094//small molecule binding GO:0012502//induction of programmed cell death;GO:0006259//DNA metabolic process;GO:0006915//apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0000076//DNA replication checkpoint gi|21450341|ref|NP_659180.1|/0/NEDD8-activating enzyme E1 regulatory subunit [Mus musculus] 12175 5802.08 11.67333333 12.13333333 0.055759367 Up 0.166083719 Bnip2 BCL2/adenovirus E1B interacting protein 2 K18448|1|0.0|720|rro:104670879|BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 - - - gi|74204524|dbj|BAE35338.1|/0/unnamed protein product [Mus musculus] 72117 4526 11.66 11.20333333 -0.057639747 Down 0.166083719 Naa50 "N(alpha)-acetyltransferase 50, NatE catalytic subunit" - GO:0044424 GO:0016407//acetyltransferase activity GO:0006473//protein acetylation "gi|148665617|gb|EDK98033.1|/2.2632e-94/N-acetyltransferase 13, isoform CRA_c, partial [Mus musculus]" 83922 3460 0.746666667 0.866666667 0.215012891 Up 0.166055512 Cep41 centrosomal protein 41 K16455|1|0.0|577|mmu:83922|centrosomal protein CEP41 GO:0005813//centrosome;GO:0005929//cilium - GO:0010927;GO:0045184//establishment of protein localization;GO:0018200//peptidyl-glutamic acid modification "gi|149065186|gb|EDM15262.1|/9.47655e-21/testis specific, 14, isoform CRA_b [Rattus norvegicus]" 77532 2952 0.85 0.73 -0.219566377 Down 0.166055512 Jrkl Jrk-like K09229|1|6e-88|328|acs:100561333|KRAB and SCAN domains-containing zinc finger protein;K19326|2|2e-70|270|lcm:102349340|nesprin-1;K05164|3|2e-52|210|lcm:102357679|interleukin 17 receptor;K11496|4|2e-27|127|mdo:100031122|centromere protein B GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding - gi|226443095|ref|NP_001028353.1|/0/jerky protein homolog-like [Mus musculus] 100039968 1139 0.74 0.863333333 0.222392421 Up 0.166055512 Gm12942 transmembrane protein 35B "K13219|1|8e-12|73.9|cmy:102934845|splicing factor, proline- and glutamine-rich" - - - gi|150010657|ref|NP_001092789.1|/2.33533e-50/uncharacterized protein ZMYM6NB precursor [Mus musculus] 224697 4068.53 7.756666667 7.41 -0.065963262 Down 0.166046109 Adamts10 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10" K08625|1|0.0|1176|mmu:224697|a disintegrin and metalloproteinase with thrombospondin motifs 10 [EC:3.4.24.-] - - - - 52858 2313 23.68666667 24.47666667 0.047331911 Up 0.1660085 Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) K00999|1|1e-108|396|mmu:52858|CDP-diacylglycerol--inositol 3-phosphatidyltransferase [EC:2.7.8.11] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0008289//lipid binding;GO:0036094//small molecule binding;GO:0017169//CDP-alcohol phosphatidyltransferase activity GO:0046474//glycerophospholipid biosynthetic process gi|28076897|ref|NP_080914.1|/1.08691e-107/CDP-diacylglycerol--inositol 3-phosphatidyltransferase [Mus musculus] 66686 3025 2.656666667 2.86 0.106397924 Up 0.165923878 Dcbld1 "discoidin, CUB and LCCL domain containing 1" K20111|1|2e-11|74.3|bfo:BRAFLDRAFT_123740|oviductin [EC:3.4.21.120];K14616|2|4e-11|73.2|tru:101079407|cubilin GO:0031224//intrinsic component of membrane - - "gi|165377069|ref|NP_079981.2|/0/discoidin, CUB and LCCL domain-containing protein 1 precursor [Mus musculus]" 74682 4376 2.526666667 2.73 0.111665603 Up 0.165923878 Wdr35 WD repeat domain 35 K19674|1|0.0|2341|mmu:74682|WD repeat-containing protein 35 - - - - 67785 7022 2.583333333 2.783333333 0.107579887 Up 0.165923878 Zmym4 "zinc finger, MYM-type 4" - - GO:0046914//transition metal ion binding GO:0000902//cell morphogenesis;GO:0006996//organelle organization gi|37359938|dbj|BAC97947.1|/0/mKIAA0425 protein [Mus musculus] 54447 4835 2.723333333 2.52 -0.111949844 Down 0.165923878 Asah2 N-acylsphingosine amidohydrolase 2 K12349|1|0.0|1500|mmu:54447|neutral ceramidase [EC:3.5.1.23] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0006643//membrane lipid metabolic process;GO:0042221//response to chemical;GO:0012501//programmed cell death "gi|148709769|gb|EDL41715.1|/0/N-acylsphingosine amidohydrolase 2, isoform CRA_a, partial [Mus musculus]" 214854 2583 2.68 2.883333333 0.105504631 Up 0.165923878 Neurl3 neuralized E3 ubiquitin protein ligase 3 K15689|1|1e-150|536|mmu:214854|E3 ubiquitin-protein ligase NEURL3 [EC:2.3.2.27] - - - - 69692 718 2.403333333 2.6 0.113474865 Up 0.165923878 Hddc2 HD domain containing 2 K07023|1|1e-102|374|mmu:69692|putative hydrolases of HD superfamily GO:0043231//intracellular membrane-bounded organelle GO:0042578//phosphoric ester hydrolase activity;GO:0043169//cation binding - "gi|148672910|gb|EDL04857.1|/5.15384e-103/HD domain containing 2, isoform CRA_a [Mus musculus]" 69878 869 23.28333333 24.06 0.047339028 Up 0.165829854 Snrpf small nuclear ribonucleoprotein polypeptide F K11098|1|4e-40|167|mmu:102638183|small nuclear ribonucleoprotein F GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding "GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter" "gi|41946811|gb|AAH66015.1|/1.07507e-40/Snrpf protein, partial [Mus musculus]" 19366 2742 0.27 0.356666667 0.401616984 Up 0.16577344 Rad54l RAD54 like (S. cerevisiae) K10875|1|0.0|1425|mmu:19366|DNA repair and recombination protein RAD54 and RAD54-like protein [EC:3.6.4.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0003676//nucleic acid binding GO:0009314//response to radiation;GO:0006996//organelle organization;GO:0000725//recombinational repair;GO:0042221//response to chemical;GO:0009314//response to radiation;GO:0006996//organelle organization;GO:0000725//recombinational repair;GO:0042221//response to chemical;GO:0009314//response to radiation;GO:0006996//organelle organization;GO:0000725//recombinational repair;GO:0042221//response to chemical gi|171906595|ref|NP_033041.3|/0/DNA repair and recombination protein RAD54-like [Mus musculus] 320965 4677 0.273333333 0.363333333 0.41063232 Up 0.16577344 4831440E17Rik RIKEN cDNA 4831440E17 gene - - - - gi|148671128|gb|EDL03075.1|/1.96038e-24/mCG147055 [Mus musculus] 434778 1536 0.36 0.273333333 -0.397335498 Down 0.16577344 Ccdc160 coiled-coil domain containing 160 - - - - gi|85702181|ref|NP_001029231.1|/0/coiled-coil domain-containing protein 160 [Mus musculus] 18708 6079.57 21.99 21.22 -0.051422948 Down 0.165651209 Pik3r1 "phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)" "K02649|1|0.0|1311|mmu:18708|phosphoinositide-3-kinase, regulatory subunit" GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0035258//steroid hormone receptor binding;GO:0017046//peptide hormone binding;GO:0019900//kinase binding;GO:0035014//phosphatidylinositol 3-kinase regulator activity;GO:0019902//phosphatase binding;GO:0052742;GO:0005167;GO:0070851//growth factor receptor binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0035258//steroid hormone receptor binding;GO:0017046//peptide hormone binding;GO:0019900//kinase binding;GO:0035014//phosphatidylinositol 3-kinase regulator activity;GO:0019902//phosphatase binding;GO:0052742;GO:0005167;GO:0070851//growth factor receptor binding;GO:0044389//ubiquitin-like protein ligase binding GO:0002027//regulation of heart rate;GO:0001952//regulation of cell-matrix adhesion;GO:0030098//lymphocyte differentiation;GO:0045445//myoblast differentiation;GO:0043434//response to peptide hormone;GO:0007162//negative regulation of cell adhesion;GO:0019318//hexose metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008217//regulation of blood pressure;GO:0042991//transcription factor import into nucleus;GO:0031960//response to corticosteroid;GO:0016477//cell migration;GO:0006508//proteolysis;GO:0009411//response to UV;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0043550//regulation of lipid kinase activity;GO:0046683//response to organophosphorus;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006464//cellular protein modification process;GO:0043066//negative regulation of apoptotic process;GO:0002027//regulation of heart rate;GO:0001952//regulation of cell-matrix adhesion;GO:0030098//lymphocyte differentiation;GO:0045445//myoblast differentiation;GO:0043434//response to peptide hormone;GO:0007162//negative regulation of cell adhesion;GO:0019318//hexose metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008217//regulation of blood pressure;GO:0042991//transcription factor import into nucleus;GO:0031960//response to corticosteroid;GO:0016477//cell migration;GO:0006508//proteolysis;GO:0009411//response to UV;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0043550//regulation of lipid kinase activity;GO:0046683//response to organophosphorus;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006464//cellular protein modification process;GO:0043066//negative regulation of apoptotic process gi|117320524|ref|NP_001070963.1|/0/phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 [Mus musculus] 99512 4223 1.88 1.713333333 -0.133926803 Down 0.165641807 Wdr47 WD repeat domain 47 K16482|1|3e-24|117|ccw:104683238|centriolar protein POC1 GO:0015630//microtubule cytoskeleton - GO:0032502//developmental process gi|28972451|dbj|BAC65679.1|/0/mKIAA0893 protein [Mus musculus] 11891 3066 5.45 5.17 -0.076091949 Down 0.165585392 Rab27a "RAB27A, member RAS oncogene family" K07885|1|3e-125|452|mmu:11891|Ras-related protein Rab-27A GO:0031513//nonmotile primary cilium;GO:0043005//neuron projection;GO:0030133//transport vesicle;GO:0030141//secretory granule;GO:0000323//lytic vacuole;GO:0048770;GO:0005771//multivesicular body;GO:0044459;GO:0031513//nonmotile primary cilium;GO:0043005//neuron projection;GO:0030133//transport vesicle;GO:0030141//secretory granule;GO:0000323//lytic vacuole;GO:0048770;GO:0005771//multivesicular body;GO:0044459;GO:0031513//nonmotile primary cilium;GO:0043005//neuron projection;GO:0030133//transport vesicle;GO:0030141//secretory granule;GO:0000323//lytic vacuole;GO:0048770;GO:0005771//multivesicular body;GO:0044459 GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0017022//myosin binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0017022//myosin binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0017022//myosin binding GO:0007599//hemostasis;GO:0001913//T cell mediated cytotoxicity;GO:0032401//establishment of melanosome localization;GO:0002323//natural killer cell activation involved in immune response;GO:0006887//exocytosis;GO:0006886//intracellular protein transport;GO:0050931//pigment cell differentiation;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction;GO:0007599//hemostasis;GO:0001913//T cell mediated cytotoxicity;GO:0032401//establishment of melanosome localization;GO:0002323//natural killer cell activation involved in immune response;GO:0006887//exocytosis;GO:0006886//intracellular protein transport;GO:0050931//pigment cell differentiation;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction;GO:0007599//hemostasis;GO:0001913//T cell mediated cytotoxicity;GO:0032401//establishment of melanosome localization;GO:0002323//natural killer cell activation involved in immune response;GO:0006887//exocytosis;GO:0006886//intracellular protein transport;GO:0050931//pigment cell differentiation;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction gi|13128964|ref|NP_076124.1|/2.35491e-124/ras-related protein Rab-27A [Mus musculus] 52874 3596 4.676666667 4.953333333 0.082919107 Up 0.165585392 Pum3 pumilio RNA-binding family member 3 K14844|1|0.0|530|mmu:52874|pumilio homology domain family member 6 - - - - 17181 3520 5.19 4.91 -0.080011514 Down 0.165585392 Matn2 matrilin 2 K19467|1|5e-113|412|asn:102381008|matrilin-3 GO:0005578//proteinaceous extracellular matrix GO:0046872//metal ion binding GO:0006935//chemotaxis;GO:0009611//response to wounding;GO:0016477//cell migration;GO:0031102//neuron projection regeneration gi|120407045|ref|NP_058042.2|/0/matrilin-2 precursor [Mus musculus] 242721 5871 1.583333333 1.746666667 0.141639298 Up 0.165538381 Klhdc7a kelch domain containing 7A K10476|1|2e-86|324|lcm:102358370|kelch repeat and BTB domain-containing protein 11 GO:0031224//intrinsic component of membrane - - gi|116063542|ref|NP_775603.2|/0/kelch domain-containing protein 7A [Mus musculus] 14158 2989.31 4.023333333 3.78 -0.090005036 Down 0.165519576 Fer fer (fms/fps related) protein kinase K08889|1|0.0|1457|mmu:14158|tyrosine-protein kinase Fer [EC:2.7.10.2] GO:0005856//cytoskeleton;GO:0031252//cell leading edge;GO:0009898//cytoplasmic side of plasma membrane;GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0005856//cytoskeleton;GO:0031252//cell leading edge;GO:0009898//cytoplasmic side of plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0044444//cytoplasmic part GO:0004713//protein tyrosine kinase activity;GO:0019900//kinase binding;GO:0050839//cell adhesion molecule binding;GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0019903//protein phosphatase binding;GO:0070851//growth factor receptor binding;GO:0017016//Ras GTPase binding;GO:0004713//protein tyrosine kinase activity;GO:0019900//kinase binding;GO:0050839//cell adhesion molecule binding;GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0019903//protein phosphatase binding;GO:0070851//growth factor receptor binding;GO:0017016//Ras GTPase binding GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002279;GO:0010761//fibroblast migration;GO:0036005;GO:0019221//cytokine-mediated signaling pathway;GO:0000904//cell morphogenesis involved in differentiation;GO:0000302//response to reactive oxygen species;GO:0002237//response to molecule of bacterial origin;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0030032//lamellipodium assembly;GO:0007049//cell cycle;GO:0033631//cell-cell adhesion mediated by integrin;GO:0045123//cellular extravasation;GO:0030041//actin filament polymerization;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0038093//Fc receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002279;GO:0010761//fibroblast migration;GO:0036005;GO:0019221//cytokine-mediated signaling pathway;GO:0000904//cell morphogenesis involved in differentiation;GO:0000302//response to reactive oxygen species;GO:0002237//response to molecule of bacterial origin;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0030032//lamellipodium assembly;GO:0007049//cell cycle;GO:0008283//cell proliferation;GO:0033631//cell-cell adhesion mediated by integrin;GO:0045123//cellular extravasation;GO:0030041//actin filament polymerization;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0038093//Fc receptor signaling pathway;GO:0008286//insulin receptor signaling pathway gi|556695416|ref|NP_001273344.1|/0/tyrosine-protein kinase Fer isoform c [Mus musculus] 69747 776 11.44666667 11 -0.057424015 Down 0.165481966 Zswim7 zinc finger SWIM-type containing 7 - GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0031647//regulation of protein stability gi|254553350|ref|NP_081474.1|/1.7744e-78/zinc finger SWIM domain-containing protein 7 [Mus musculus] 260423 903 0.293333333 0.383333333 0.386058432 Up 0.165472564 Hist1h3f "histone cluster 1, H3f" K11253|1|3e-67|257|xtr:100493041|histone H3 - - - gi|847156416|ref|XP_002945479.3|/2.70442e-66/PREDICTED: histone H3-like [Xenopus tropicalis] 235505 5883 0.376666667 0.286666667 -0.393914208 Down 0.165472564 Cd109 CD109 antigen K06530|1|0.0|2685|mmu:235505|CD109 antigen - - - - 236193 3990 0.37 0.283333333 -0.38502493 Down 0.165472564 Zfp709 zinc finger protein 709 K09228|1|0.0|1572|mmu:236193|KRAB domain-containing zinc finger protein GO:0044464;GO:0016020//membrane GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding "GO:0009408//response to heat;GO:0006351//transcription, DNA-templated;GO:0032496//response to lipopolysaccharide" gi|161086992|ref|NP_663599.3|/0/zinc finger protein 709 [Mus musculus] 22673 3557 0.38 0.29 -0.389946518 Down 0.165472564 Zfp185 zinc finger protein 185 K16580|1|8e-10|69.3|shr:100931839|SLAIN motif-containing protein 1/2 GO:0043232;GO:0043232 GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - "gi|148694607|gb|EDL26554.1|/0/zinc finger protein 185, isoform CRA_a, partial [Mus musculus]" 93883 3034 0.156666667 0.233333333 0.574694165 Up 0.165350333 Pcdhb12 protocadherin beta 12 K16494|1|0.0|1414|mmu:93883|protocadherin beta GO:0016021//integral component of membrane;GO:0030054//cell junction GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|18087787|ref|NP_444367.1|/0/protocadherin beta 12 precursor [Mus musculus] 402773 2562.43 0.176666667 0.26 0.557481764 Up 0.165350333 D030018L15Rik nuclear receptor coactivator 2 pseudogene - - - - gi|74193606|dbj|BAE22764.1|/5.69e-78/unnamed protein product [Mus musculus] 78917 629 0.246666667 0.166666667 -0.565597176 Down 0.165350333 4930455G09Rik RIKEN cDNA 4930455G09 gene - - - - - 21336 5036 0.246666667 0.166666667 -0.565597176 Down 0.165350333 Tacr1 tachykinin receptor 1 K04222|1|0.0|773|mmu:21336|tachykinin receptor 1 GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0044424 GO:0004995//tachykinin receptor activity "GO:0006954//inflammatory response;GO:0033555//multicellular organismal response to stress;GO:0019229//regulation of vasoconstriction;GO:0007631//feeding behavior;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0009612//response to mechanical stimulus;GO:0046541//saliva secretion;GO:0007613//memory;GO:0001508//action potential;GO:0001503//ossification;GO:0014072//response to isoquinoline alkaloid;GO:0035813//regulation of renal sodium excretion;GO:0007271//synaptic transmission, cholinergic;GO:0002684//positive regulation of immune system process;GO:0007600//sensory perception;GO:0007612//learning;GO:0000302//response to reactive oxygen species;GO:0043627//response to estrogen;GO:0046879//hormone secretion;GO:0043114//regulation of vascular permeability;GO:0007186//G-protein coupled receptor signaling pathway;GO:0032233//positive regulation of actin filament bundle assembly;GO:0010631//epithelial cell migration;GO:0045987//positive regulation of smooth muscle contraction;GO:0014909//smooth muscle cell migration;GO:0014832//urinary bladder smooth muscle contraction;GO:0097305//response to alcohol;GO:0007320//insemination;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0002035//brain renin-angiotensin system;GO:0051480//regulation of cytosolic calcium ion concentration" gi|31543840|ref|NP_033339.2|/0/substance-P receptor [Mus musculus] 338348 2829.31 0.17 0.25 0.556393349 Up 0.165350333 Ttc16 tetratricopeptide repeat domain 16 K09667|1|1e-08|65.1|bfo:BRAFLDRAFT_117202|protein O-GlcNAc transferase [EC:2.4.1.255];K16365|5|5e-06|56.2|cmk:103181952|small glutamine-rich tetratricopeptide repeat-containing protein alpha - - - gi|225543306|ref|NP_796358.2|/0/tetratricopeptide repeat protein 16 isoform a [Mus musculus] 237611 1790 0.163333333 0.24 0.555215157 Up 0.165350333 Stac3 SH3 and cysteine rich domain 3 K04705|1|7e-08|61.6|cmk:103189024|signal transducing adaptor molecule;K19862|2|9e-08|61.2|dan:Dana_GF15078|NCK adaptor protein 2;K07366|4|9e-08|61.2|pss:102449081|GRB2-related adaptor protein 2 - GO:0005515//protein binding - "gi|148692560|gb|EDL24507.1|/3.37805e-159/SH3 and cysteine rich domain 3, isoform CRA_b, partial [Mus musculus]" 100503434 1543 0.16 0.236666667 0.564784619 Up 0.165350333 Gm19689 "predicted gene, 19689" - - - - - 11982 5469 0.536666667 0.433333333 -0.308549065 Down 0.165303321 Atp10a "ATPase, class V, type 10A" K01530|1|0.0|2814|mmu:11982|phospholipid-translocating ATPase [EC:3.6.3.1] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0003824//catalytic activity GO:0006811//ion transport;GO:0006869//lipid transport "gi|148689911|gb|EDL21858.1|/0/ATPase, class V, type 10A, isoform CRA_b, partial [Mus musculus]" 16987 6339 0.496666667 0.4 -0.312277925 Down 0.165303321 Lss lanosterol synthase K01852|1|0.0|1528|mmu:16987|lanosterol synthase [EC:5.4.99.7] - - - - 70481 2360 0.15 0.076666667 -0.96829114 Down 0.165284516 Pnma1 paraneoplastic antigen MA1 K17561|1|4e-22|109|cge:103164277|coiled-coil domain-containing protein 8;K02183|4|9e-14|81.6|umr:103657204|calmodulin GO:0005924//cell-substrate adherens junction;GO:0031981//nuclear lumen - - gi|26390362|dbj|BAC25885.1|/0/unnamed protein product [Mus musculus] 22412 4519 0.136666667 0.07 -0.965234582 Down 0.165284516 Wnt9b "wingless-type MMTV integration site family, member 9B" "K01064|1|7e-170|601|mmu:22412|wingless-type MMTV integration site family, member 9" GO:0031012//extracellular matrix GO:0005515//protein binding GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0046546//development of primary male sexual characteristics;GO:0072172//mesonephric tubule formation;GO:0008356//asymmetric cell division;GO:0001736//establishment of planar polarity;GO:0006468//protein phosphorylation;GO:0035567//non-canonical Wnt signaling pathway;GO:0044093;GO:0090066;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048704//embryonic skeletal system morphogenesis gi|880882276|ref|XP_005070115.2|/3.1884e-173/PREDICTED: protein Wnt-9b [Mesocricetus auratus] 245631 4182 0.08 0.15 0.906890596 Up 0.165284516 Mum1l1 melanoma associated antigen (mutated) 1-like 1 - - - - "gi|148691959|gb|EDL23906.1|/0/melanoma associated antigen (mutated) 1-like 1, partial [Mus musculus]" 73862 753 0.14 0.073333333 -0.932885804 Down 0.165284516 4930415F15Rik RIKEN cDNA 4930415F15 gene - - - - gi|755536571|ref|XP_006514887.2|/4.29616e-82/PREDICTED: uncharacterized protein C7orf72 homolog isoform X4 [Mus musculus] 20840 2382 0.146666667 0.076666667 -0.935869663 Down 0.165284516 Stac src homology three (SH3) and cysteine rich domain K06114|1|5e-09|66.2|ame:551291|spectrin alpha - - - - 208084 3680 0.083333333 0.156666667 0.910732662 Up 0.165284516 Pif1 PIF1 5'-to-3' DNA helicase K15255|1|0.0|1231|mmu:208084|ATP-dependent DNA helicase PIF1 [EC:3.6.4.12] "GO:0043231//intracellular membrane-bounded organelle;GO:0000781//chromosome, telomeric region" GO:0032550;GO:0004003//ATP-dependent DNA helicase activity;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0033678 GO:0000723//telomere maintenance;GO:0051348//negative regulation of transferase activity "gi|148694152|gb|EDL26099.1|/0/expressed sequence AI449441, isoform CRA_a, partial [Mus musculus]" 100038358 2796 0.15 0.08 -0.906890596 Down 0.165284516 Gm10857 predicted gene 10857 K11985|1|2e-160|568|mmu:22036|TRAF-interacting protein [EC:2.3.2.27] GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0044424 GO:0046914//transition metal ion binding;GO:0004871//signal transducer activity;GO:0046914//transition metal ion binding;GO:0004871//signal transducer activity GO:0007154//cell communication;GO:0007154//cell communication gi|31560535|ref|NP_035764.2|/1.98145e-159/E3 ubiquitin-protein ligase TRAIP [Mus musculus] 20852 3805 24.22666667 23.47666667 -0.045368337 Down 0.165265711 Stat6 signal transducer and activator of transcription 6 K11225|1|0.0|1651|mmu:20852|signal transducer and activator of transcription 6 GO:0031981//nuclear lumen;GO:0000785//chromatin GO:0005515//protein binding;GO:0060089;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046872//metal ion binding GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0045830//positive regulation of isotype switching;GO:0022612//gland morphogenesis;GO:0010033//response to organic substance;GO:0050673//epithelial cell proliferation;GO:0002295//T-helper cell lineage commitment;GO:0002828//regulation of type 2 immune response gi|128485774|ref|NP_033310.2|/0/signal transducer and transcription activator 6 [Mus musculus] 67881 1753.76 19.93333333 20.68333333 0.053285726 Up 0.165265711 Mdp1 magnesium-dependent phosphatase 1 K17619|1|8e-91|337|mmu:67881|magnesium-dependent phosphatase 1 [EC:3.1.3.48 3.1.3.-] - GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding GO:0006040//amino sugar metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006040//amino sugar metabolic process;GO:0006796//phosphate-containing compound metabolic process gi|12963663|ref|NP_075886.1|/7.11063e-90/magnesium-dependent phosphatase 1 [Mus musculus] 622319 2562 1.18 1.323333333 0.165389647 Up 0.165040054 Gm6313 predicted gene 6313 K19871|1|1e-17|91.3|rno:686412|sal-like protein - - GO:0007275//multicellular organism development;GO:0048856//anatomical structure development;GO:0044767//single-organism developmental process;GO:0009987//cellular process gi|74137914|dbj|BAE24099.1|/1.47558e-52/unnamed protein product [Mus musculus] 71254 3173 1.14 1.283333333 0.170862121 Up 0.165040054 Naif1 nuclear apoptosis inducing factor 1 "K14684|1|4e-30|136|ngi:103727445|solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41" GO:0043231//intracellular membrane-bounded organelle - GO:0012502//induction of programmed cell death gi|37059816|ref|NP_919316.1|/1.16024e-118/nuclear apoptosis-inducing factor 1 [Mus musculus] 12006 4279 0.923333333 1.056666667 0.194596864 Up 0.165002445 Axin2 axin 2 K04385|1|0.0|1524|mmu:12006|axin 2 - - - gi|40254370|ref|NP_056547.3|/0/axin-2 [Mus musculus] 243510 3129 0.966666667 1.1 0.186413124 Up 0.165002445 Ccdc142 coiled-coil domain containing 142 K16865|1|3e-66|256|cmy:102941005|programmed cell death protein 4 - - - gi|124486907|ref|NP_001074735.1|/0/coiled-coil domain-containing protein 142 [Mus musculus] 330502 2030 0.926666667 1.06 0.193941883 Up 0.165002445 Zfp82 zinc finger protein 82 K09228|1|3e-36|155|mmu:330502|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|26332050|dbj|BAC29755.1|/4.05115e-41/unnamed protein product [Mus musculus] 51799 2430 0.893333333 1.02 0.191298652 Up 0.165002445 Rundc3a RUN domain containing 3A "K05659|1|2e-29|134|oas:101122517|ATP-binding cassette, subfamily B (MDR/TAP), member 4 [EC:3.6.3.44];K12482|2|2e-22|110|pbi:103053920|RUN and FYVE domain-containing protein 1" GO:0016020//membrane;GO:0016020//membrane GO:0008047//enzyme activator activity;GO:0051427//hormone receptor binding;GO:0008047//enzyme activator activity;GO:0051427//hormone receptor binding GO:0031281//positive regulation of cyclase activity;GO:0006182//cGMP biosynthetic process;GO:0031281//positive regulation of cyclase activity;GO:0006182//cGMP biosynthetic process gi|7949125|ref|NP_058039.1|/0/RUN domain-containing protein 3A isoform 1 [Mus musculus] 73061 3276 0.886666667 1.013333333 0.192645078 Up 0.165002445 Cldn34c1 claudin 34C1 K06087|1|4e-65|252|mmu:73934|claudin;K18625|4|3e-29|133|cge:100752637|protein Shroom;K11290|5|3e-11|68.6|rno:317165|template-activating factor I - - - gi|110625950|ref|NP_082702.1|/9.35537e-119/claudin 34C1 isoform 1 [Mus musculus] 59015 5684 0.92 1.05 0.190683562 Up 0.165002445 Nup160 nucleoporin 160 K14303|1|0.0|2699|mmu:59015|nuclear pore complex protein Nup160 GO:0005643//nuclear pore GO:0005215//transporter activity GO:0006405//RNA export from nucleus;GO:0045184//establishment of protein localization "gi|148695543|gb|EDL27490.1|/0/nucleoporin 160, isoform CRA_b, partial [Mus musculus]" 26403 3919 22.28666667 21.54666667 -0.048716157 Down 0.164964835 Map3k11 mitogen-activated protein kinase kinase kinase 11 K04419|1|0.0|1276|mmu:26403|mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25] GO:0005815//microtubule organizing center GO:0032550;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0017048//Rho GTPase binding;GO:0004709//MAP kinase kinase kinase activity GO:0000186//activation of MAPKK activity;GO:0051318;GO:0007254//JNK cascade;GO:0043065//positive regulation of apoptotic process;GO:0000187//activation of MAPK activity gi|31543234|ref|NP_071295.2|/0/mitogen-activated protein kinase kinase kinase 11 [Mus musculus] 246696 1569 21.64333333 22.38 0.048287328 Up 0.164964835 Slc25a28 "solute carrier family 25, member 28" "K15113|1|0.0|637|mmu:246696|solute carrier family 25 (mitochondrial iron transporter), member 28/37" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0044765//single-organism transport;GO:0055080//cation homeostasis gi|21553115|ref|NP_660138.1|/2.23098e-180/mitoferrin-2 [Mus musculus] 18203 1175 20.28333333 21.02 0.051467907 Up 0.164964835 Ntan1 N-terminal Asn amidase K14662|1|1e-178|627|mmu:18203|protein N-terminal asparagine amidohydrolase [EC:3.5.1.-] GO:0044424 "GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0007626//locomotory behavior;GO:0007611//learning or memory gi|6754902|ref|NP_035076.1|/1.17382e-177/protein N-terminal asparagine amidohydrolase [Mus musculus] 18295 2540 20.09666667 20.83333333 0.05193746 Up 0.164964835 Ogn osteoglycin "K08126|1|3e-163|578|mmu:18295|osteoglycin (osteoinductive factor, mimecan)" GO:0044421;GO:0031012//extracellular matrix GO:0005102//receptor binding GO:0008285//negative regulation of cell proliferation gi|6679166|ref|NP_032786.1|/2.25458e-162/mimecan precursor [Mus musculus] 76041 2496 0.676666667 0.57 -0.247483402 Down 0.16494603 Ccdc125 coiled-coil domain containing 125 "K04679|1|1e-119|433|ccw:104695849|MAD, mothers against decapentaplegic interacting protein;K05765|2|6e-36|155|pps:103783923|cofilin;K20282|3|2e-08|63.9|spu:578096|GRIP and coiled-coil domain-containing protein 2" GO:0044424 - - gi|270288750|ref|NP_001161858.1|/0/coiled-coil domain-containing protein 125 isoform B [Mus musculus] 67169 1213 0.576666667 0.686666667 0.2518723 Up 0.16494603 Nradd neurotrophin receptor associated death domain K02583|1|7e-43|177|shr:100931911|nerve growth factor receptor (TNFR superfamily member 16) GO:0043005//neuron projection;GO:0031252//cell leading edge;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0044297//cell body - GO:0007275//multicellular organism development;GO:0012501//programmed cell death;GO:0007154//cell communication gi|568964093|ref|XP_006512303.1|/3.38316e-143/PREDICTED: death domain-containing membrane protein NRADD isoform X1 [Mus musculus] 242126 6641 0.573333333 0.683333333 0.253215345 Up 0.16494603 Slc22a15 "solute carrier family 22 (organic anion/cation transporter), member 15" "K08211|1|0.0|932|mmu:242126|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 15" GO:0031224//intrinsic component of membrane GO:0005215//transporter activity GO:0044765//single-organism transport;GO:0044763 gi|260166627|ref|NP_001034460.2|/0/solute carrier family 22 member 15 [Mus musculus] 11920 11964 0.56 0.666666667 0.251538767 Up 0.16494603 Atm ataxia telangiectasia mutated K04728|1|0.0|5925|mmu:11920|ataxia telangiectasia mutated family protein [EC:2.7.11.1] GO:0031981//nuclear lumen;GO:0031982//vesicle;GO:0044427;GO:0015630//microtubule cytoskeleton GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0005515//protein binding;GO:0052742;GO:0003676//nucleic acid binding "GO:0043065//positive regulation of apoptotic process;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0010332//response to gamma radiation;GO:0009952//anterior/posterior pattern specification;GO:0006661//phosphatidylinositol biosynthetic process;GO:0016572//histone phosphorylation;GO:0007569//cell aging;GO:0002329//pre-B cell differentiation;GO:0007127//meiosis I;GO:0000077//DNA damage checkpoint;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0007276//gamete generation;GO:0030888//regulation of B cell proliferation;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0000725//recombinational repair;GO:0007417//central nervous system development;GO:0070997//neuron death;GO:0030163//protein catabolic process" gi|163838660|ref|NP_031525.2|/0/serine-protein kinase ATM [Mus musculus] 67038 1887 0.586666667 0.7 0.254813899 Up 0.16494603 2010109I03Rik RIKEN cDNA 2010109I03 gene K06846|1|6e-56|221|mmu:67038|lymphocyte antigen 6 complex locus protein D/E/G6/H - - - gi|13385422|ref|NP_080205.1|/4.88185e-55/intectin precursor [Mus musculus] 18742 1379 0.723333333 0.61 -0.245851394 Down 0.16494603 Pitx3 paired-like homeodomain transcription factor 3 K09357|1|6e-125|447|ssc:100154216|paired-like homeodomain transcription factor 3 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding "GO:0007420//brain development;GO:0044708//single-organism behavior;GO:0006351//transcription, DNA-templated;GO:0002088//lens development in camera-type eye;GO:0030182//neuron differentiation" "gi|148710035|gb|EDL41981.1|/4.50648e-134/paired-like homeodomain transcription factor 3, partial [Mus musculus]" 215351 4976 7.66 7.316666667 -0.066157858 Down 0.164927226 Senp6 SUMO/sentrin specific peptidase 6 K08595|1|0.0|2125|mmu:215351|sentrin-specific protease 6 [EC:3.4.22.68] GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0019783//ubiquitin-like protein-specific protease activity GO:0043254//regulation of protein complex assembly;GO:0070646//protein modification by small protein removal gi|46560561|ref|NP_666115.2|/0/sentrin-specific protease 6 isoform 2 [Mus musculus] 228790 6674 6.8 6.463333333 -0.073256349 Down 0.164927226 Asxl1 additional sex combs like 1 K11471|1|0.0|2718|mmu:228790|additional sex combs-like protein - - - gi|28972558|dbj|BAC65695.1|/0/mKIAA0978 protein [Mus musculus] 18654 1431.78 7.18 7.516666667 0.066109184 Up 0.164927226 Pgf placental growth factor K16859|1|1e-77|293|mmu:18654|placenta growth factor GO:0044421;GO:0044421 GO:0042802//identical protein binding;GO:0005126//cytokine receptor binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0005126//cytokine receptor binding;GO:0046983//protein dimerization activity GO:0048869//cellular developmental process;GO:0001525//angiogenesis;GO:0044703;GO:0009725//response to hormone;GO:0009887//organ morphogenesis;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048522;GO:0001935//endothelial cell proliferation;GO:0006950//response to stress;GO:0048869//cellular developmental process;GO:0001525//angiogenesis;GO:0044703;GO:0009725//response to hormone;GO:0009887//organ morphogenesis;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048522;GO:0001935//endothelial cell proliferation;GO:0006950//response to stress "gi|148670906|gb|EDL02853.1|/6.63702e-79/placental growth factor, isoform CRA_b [Mus musculus]" 218877 3686 6.976666667 6.636666667 -0.072079091 Down 0.164927226 Sema3g "sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G" K06840|1|0.0|1501|mmu:218877|semaphorin 3 - - GO:0032502//developmental process gi|84794605|ref|NP_001020550.1|/0/semaphorin-3G precursor [Mus musculus] 227541 6742 0.313333333 0.406666667 0.376148486 Up 0.164899018 Camk1d calcium/calmodulin-dependent protein kinase ID K08794|1|0.0|667|rno:307124|calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17] - - - - 433323 3998 0.296666667 0.386666667 0.382247564 Up 0.164899018 Sgpp2 sphingosine-1-phosphate phosphotase 2 K04717|1|0.0|676|mmu:433323|sphingosine-1-phosphate phosphotase 2 [EC:3.1.3.-] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0016791//phosphatase activity GO:0006066//alcohol metabolic process;GO:0006665//sphingolipid metabolic process;GO:0006796//phosphate-containing compound metabolic process gi|51921345|ref|NP_001004173.1|/0/sphingosine-1-phosphate phosphatase 2 [Mus musculus] 16529 3364 0.31 0.403333333 0.379704426 Up 0.164899018 Kcnk5 "potassium channel, subfamily K, member 5" K04916|1|0.0|928|mmu:16529|potassium channel subfamily K member 5 - - - - 239554 4812 0.386666667 0.296666667 -0.382247564 Down 0.164899018 Foxred2 FAD-dependent oxidoreductase domain containing 2 K00485|1|1e-09|68.9|spu:578464|dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8] GO:0044432;GO:0044432 GO:0003824//catalytic activity;GO:0000166//nucleotide binding;GO:0003824//catalytic activity;GO:0000166//nucleotide binding GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044710;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044710 gi|269914150|ref|NP_001017983.2|/0/FAD-dependent oxidoreductase domain-containing protein 2 precursor [Mus musculus] 100041678 1982 0.31 0.403333333 0.379704426 Up 0.164899018 Gm3500 predicted gene 3500 "K03844|1|2e-16|90.5|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - gi|755546841|ref|XP_011243026.1|/1.2038e-121/PREDICTED: predicted gene 3264 isoform X1 [Mus musculus] 226090 5394 2.336666667 2.153333333 -0.117880279 Down 0.164852006 Ermp1 endoplasmic reticulum metallopeptidase 1 - GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0043169//cation binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process "gi|148709742|gb|EDL41688.1|/0/mCG124990, isoform CRA_b, partial [Mus musculus]" 100678 1554 2.37 2.186666667 -0.116153745 Down 0.164852006 Psph phosphoserine phosphatase K01079|1|9e-121|436|mmu:100678|phosphoserine phosphatase [EC:3.1.3.3] - - - gi|19527116|ref|NP_598661.1|/7.44774e-120/phosphoserine phosphatase [Mus musculus] 69256 5487 2.053333333 2.23 0.11907586 Up 0.164852006 Zfp397 zinc finger protein 397 K09230|1|0.0|1104|mmu:69256|SCAN domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0044764;GO:0006351//transcription, DNA-templated" "gi|148664569|gb|EDK96985.1|/0/zinc finger protein 397, isoform CRA_a, partial [Mus musculus]" 16410 7055 1.376666667 1.53 0.152352372 Up 0.164842604 Itgav integrin alpha V K06487|1|0.0|1992|mmu:16410|integrin alpha V - - - - 77059 3243 0.176666667 0.256666667 0.538866086 Up 0.164842604 4931408D14Rik RIKEN cDNA 4931408D14 gene - - - - - 11302 5279.57 1.46 1.313333333 -0.15273524 Down 0.164842604 Aatk apoptosis-associated tyrosine kinase K17480|1|0.0|2127|mmu:11302|lemur tyrosine kinase 1 [EC:2.7.10.1] GO:0030426//growth cone;GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0030426//growth cone;GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0030426//growth cone;GO:0031224//intrinsic component of membrane;GO:0005768//endosome GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity GO:0007265//Ras protein signal transduction;GO:0007417//central nervous system development;GO:0012501//programmed cell death;GO:0030308//negative regulation of cell growth;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007265//Ras protein signal transduction;GO:0007417//central nervous system development;GO:0012501//programmed cell death;GO:0030308//negative regulation of cell growth;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007265//Ras protein signal transduction;GO:0007417//central nervous system development;GO:0012501//programmed cell death;GO:0030308//negative regulation of cell growth;GO:0018108//peptidyl-tyrosine phosphorylation gi|39104555|dbj|BAC41437.2|/0/mKIAA0641 protein [Mus musculus] 21349 4237 1.503333333 1.353333333 -0.151647706 Down 0.164842604 Tal1 T cell acute lymphocytic leukemia 1 K09068|1|2e-137|493|mmu:21349|T-cell acute lymphocytic leukemia protein GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0019899//enzyme binding;GO:0008134//transcription factor binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0019899//enzyme binding;GO:0008134//transcription factor binding" GO:0000278//mitotic cell cycle;GO:0048469//cell maturation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030219//megakaryocyte differentiation;GO:0006461//protein complex assembly;GO:0021781//glial cell fate commitment;GO:0008283//cell proliferation;GO:0048522;GO:0030218//erythrocyte differentiation;GO:0002761//regulation of myeloid leukocyte differentiation;GO:0030851//granulocyte differentiation;GO:0001672//regulation of chromatin assembly or disassembly;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0044708//single-organism behavior;GO:0021515//cell differentiation in spinal cord;GO:0000278//mitotic cell cycle;GO:0048469//cell maturation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030219//megakaryocyte differentiation;GO:0006461//protein complex assembly;GO:0021781//glial cell fate commitment;GO:0008283//cell proliferation;GO:0048522;GO:0030218//erythrocyte differentiation;GO:0002761//regulation of myeloid leukocyte differentiation;GO:0030851//granulocyte differentiation;GO:0001672//regulation of chromatin assembly or disassembly;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0044708//single-organism behavior;GO:0021515//cell differentiation in spinal cord gi|568928718|ref|XP_006502972.1|/4.51147e-137/PREDICTED: T-cell acute lymphocytic leukemia protein 1 homolog isoform X2 [Mus musculus] 12361 8327.58 1.49 1.34 -0.15307933 Down 0.164842604 Cask calcium/calmodulin-dependent serine protein kinase (MAGUK family) K06103|1|0.0|1794|pale:102881573|calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1] GO:0034399//nuclear periphery;GO:0097060//synaptic membrane;GO:0005578//proteinaceous extracellular matrix;GO:0031090//organelle membrane;GO:0005856//cytoskeleton;GO:0030054//cell junction;GO:0044459;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0034399//nuclear periphery;GO:0097060//synaptic membrane;GO:0005578//proteinaceous extracellular matrix;GO:0031090//organelle membrane;GO:0030054//cell junction;GO:0044459;GO:0044444//cytoplasmic part;GO:0034399//nuclear periphery;GO:0097060//synaptic membrane;GO:0005578//proteinaceous extracellular matrix;GO:0031090//organelle membrane;GO:0005856//cytoskeleton;GO:0030054//cell junction;GO:0044459;GO:0044444//cytoplasmic part;GO:0034399//nuclear periphery;GO:0097060//synaptic membrane;GO:0005578//proteinaceous extracellular matrix;GO:0031090//organelle membrane;GO:0005856//cytoskeleton;GO:0030054//cell junction;GO:0044459;GO:0044444//cytoplasmic part "GO:0032550;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032550;GO:0004672//protein kinase activity;GO:0019904//protein domain specific binding;GO:0032550;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032550;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0001952//regulation of cell-matrix adhesion;GO:0006366//transcription from RNA polymerase II promoter;GO:0008285//negative regulation of cell proliferation;GO:0032102;GO:0034767//positive regulation of ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0001952//regulation of cell-matrix adhesion;GO:0006366//transcription from RNA polymerase II promoter;GO:0015031//protein transport;GO:0006796//phosphate-containing compound metabolic process;GO:0008285//negative regulation of cell proliferation;GO:0032102;GO:0006464//cellular protein modification process;GO:0034767//positive regulation of ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0001952//regulation of cell-matrix adhesion;GO:0006366//transcription from RNA polymerase II promoter;GO:0008285//negative regulation of cell proliferation;GO:0032102;GO:0034767//positive regulation of ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0001952//regulation of cell-matrix adhesion;GO:0006366//transcription from RNA polymerase II promoter;GO:0008285//negative regulation of cell proliferation;GO:0032102;GO:0006464//cellular protein modification process;GO:0034767//positive regulation of ion transmembrane transport;GO:0070588//calcium ion transmembrane transport gi|548961101|ref|NP_001271434.1|/0/peripheral plasma membrane protein CASK isoform 3 [Mus musculus] 72309 1744 0.423333333 0.52 0.296717532 Up 0.164804995 Tmem158 transmembrane protein 158 K06732|1|7e-10|68.2|cmy:102931396|CUB domain-containing protein 1 GO:0031224//intrinsic component of membrane GO:0033218//amide binding - gi|81891589|sp|Q6F5E0.1|TM158_MOUSE/6.90323e-109/RecName: Full=Transmembrane protein 158; AltName: Full=40 kDa BINP-binding protein; Short=p40BBP; AltName: Full=Ras-induced senescence protein 1; Flags: Precursor 83408 2145 0.423333333 0.52 0.296717532 Up 0.164804995 Gimap3 "GTPase, IMAP family member 3" - GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane GO:0032550 "GO:0006915//apoptotic process;GO:0048871//multicellular organismal homeostasis;GO:0002260//lymphocyte homeostasis;GO:0006809//nitric oxide biosynthetic process;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0002361//CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0042391//regulation of membrane potential;GO:0010522//regulation of calcium ion transport into cytosol;GO:0009895;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0002370;GO:0000002//mitochondrial genome maintenance;GO:0042492//gamma-delta T cell differentiation;GO:0001773//myeloid dendritic cell activation;GO:0006839//mitochondrial transport;GO:0001818//negative regulation of cytokine production" gi|13569476|gb|AAK31138.1|AF337052_1/1.61096e-150/immunity-associated nucleotide 4 [Mus musculus] 170740 5021 0.546666667 0.443333333 -0.302269569 Down 0.164804995 Zfp287 zinc finger protein 287 K09229|1|0.0|1588|mmu:170740|KRAB and SCAN domains-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0044764;GO:0006351//transcription, DNA-templated;GO:0001817//regulation of cytokine production" gi|113865959|ref|NP_573471.2|/0/zinc finger protein 287 [Mus musculus] 14489 4042 10.49666667 10.05333333 -0.062257329 Down 0.16478619 Mtpn myotrophin K10380|1|6e-13|79.7|nvi:100122475|ankyrin GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0044444//cytoplasmic part GO:0005488//binding GO:0042246//tissue regeneration;GO:0014706//striated muscle tissue development;GO:0006412//translation;GO:0021533//cell differentiation in hindbrain;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0003300//cardiac muscle hypertrophy;GO:0010604;GO:0009712//catechol-containing compound metabolic process;GO:0042692//muscle cell differentiation;GO:0016049//cell growth;GO:0051016//barbed-end actin filament capping gi|6679961|ref|NP_032124.1|/6.49128e-61/myotrophin [Mus musculus] 54369 1025 9.973333333 10.41 0.061822394 Up 0.16478619 Nme6 NME/NM23 nucleoside diphosphate kinase 6 K00940|1|1e-106|388|mmu:54369|nucleoside-diphosphate kinase [EC:2.7.4.6] GO:0043231//intracellular membrane-bounded organelle "GO:0032550;GO:0043169//cation binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0009209;GO:0009152//purine ribonucleotide biosynthetic process;GO:0007067//mitotic nuclear division;GO:0016049//cell growth;GO:0009132//nucleoside diphosphate metabolic process gi|9055290|ref|NP_061227.1|/9.70863e-106/nucleoside diphosphate kinase 6 [Mus musculus] 77116 3036 10.2 9.76 -0.063616099 Down 0.16478619 Mtmr2 myotubularin related protein 2 K18081|1|0.0|1215|mmu:77116|myotubularin-related protein 1/2 [EC:3.1.3.64 3.1.3.95] GO:0044327//dendritic spine head;GO:0031090//organelle membrane;GO:0005769//early endosome;GO:0030136//clathrin-coated vesicle;GO:0044327//dendritic spine head;GO:0031090//organelle membrane;GO:0005769//early endosome;GO:0030136//clathrin-coated vesicle GO:0004721//phosphoprotein phosphatase activity;GO:0042802//identical protein binding;GO:0004721//phosphoprotein phosphatase activity;GO:0042802//identical protein binding GO:0010605;GO:0002090//regulation of receptor internalization;GO:0032388//positive regulation of intracellular transport;GO:0031641//regulation of myelination;GO:0045837//negative regulation of membrane potential;GO:0046474//glycerophospholipid biosynthetic process;GO:0046488//phosphatidylinositol metabolic process;GO:0051259//protein oligomerization;GO:0010927;GO:0006470//protein dephosphorylation;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0043954//cellular component maintenance;GO:0030182//neuron differentiation;GO:0010605;GO:0002090//regulation of receptor internalization;GO:0032388//positive regulation of intracellular transport;GO:0031641//regulation of myelination;GO:0045837//negative regulation of membrane potential;GO:0046474//glycerophospholipid biosynthetic process;GO:0046488//phosphatidylinositol metabolic process;GO:0051259//protein oligomerization;GO:0010927;GO:0006470//protein dephosphorylation;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0043954//cellular component maintenance;GO:0030182//neuron differentiation gi|568960216|ref|XP_006510740.1|/0/PREDICTED: myotubularin-related protein 2 isoform X2 [Mus musculus] 15213 2215 10.84 11.28333333 0.057828576 Up 0.16478619 Hey1 hairy/enhancer-of-split related with YRPW motif 1 K09091|1|5e-118|427|mmu:15213|hairy and enhancer of split related with YRPW motif GO:0043231//intracellular membrane-bounded organelle "GO:0005515//protein binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0003696//satellite DNA binding" GO:0003272//endocardial cushion formation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007219//Notch signaling pathway;GO:0003181//atrioventricular valve morphogenesis;GO:0048568//embryonic organ development;GO:0035907//dorsal aorta development;GO:0001649//osteoblast differentiation;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0001837//epithelial to mesenchymal transition;GO:0060837//blood vessel endothelial cell differentiation;GO:0003188//heart valve formation;GO:0003177;GO:0043392//negative regulation of DNA binding;GO:0009798//axis specification;GO:0003281//ventricular septum development;GO:0001570//vasculogenesis;GO:0030182//neuron differentiation gi|117606332|ref|NP_034553.2|/4.17534e-117/hairy/enhancer-of-split related with YRPW motif protein 1 [Mus musculus] 29818 2768 1672.136667 1720.586667 0.041207797 Up 0.164663959 Hspb7 "heat shock protein family, member 7 (cardiovascular)" K09546|1|6e-76|288|ggo:101134382|heat shock protein beta-7 GO:0043232;GO:0016604//nuclear body GO:0005515//protein binding GO:0035966//response to topologically incorrect protein;GO:0044057 gi|426327968|ref|XP_004024780.1|/5.14894e-75/PREDICTED: heat shock protein beta-7 [Gorilla gorilla gorilla] 28080 772 1479.45 1520.79 0.039760011 Up 0.164645154 Atp5o "ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit" K02137|1|8e-112|405|mmu:28080|F-type H+-transporting ATPase subunit O "GO:0005743//mitochondrial inner membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain" GO:0005515//protein binding;GO:0019829//cation-transporting ATPase activity;GO:0008289//lipid binding GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0009154//purine ribonucleotide catabolic process;GO:0006839//mitochondrial transport "gi|20070412|ref|NP_613063.1|/5.99143e-111/ATP synthase subunit O, mitochondrial precursor [Mus musculus]" 69295 893 0.146666667 0.08 -0.874469118 Down 0.164626349 Far1os "fatty acyl CoA reductase 1, opposite strand" K13356|1|9e-07|56.6|rno:293173|alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84] - - - - 103655 2956 0.086666667 0.16 0.884522783 Up 0.164626349 Sec14l4 SEC14-like lipid binding 4 K17981|1|2e-132|476|fch:102055515|mitochondrial fission process protein 1;K16302|2|1e-129|467|tru:101066937|metal transporter CNNM;K01019|3|4e-30|136|umr:103681122|galactosylceramide sulfotransferase [EC:2.8.2.11];K12850|4|2e-15|87.4|tsp:Tsp_07066|pre-mRNA-splicing factor 38B;K19625|5|3e-10|70.5|cin:100185518|retinaldehyde-binding protein 1 GO:0044464;GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0051234//establishment of localization gi|22165368|ref|NP_666125.1|/0/SEC14-like protein 4 [Mus musculus] 208158 3290 0.186666667 0.27 0.532495081 Up 0.164626349 Map6d1 MAP6 domain containing 1 K10432|1|3e-09|67.4|rro:104665196|microtubule-associated protein 6 "GO:0015630//microtubule cytoskeleton;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0015631//tubulin binding GO:0006500;GO:0007019//microtubule depolymerization gi|74201189|dbj|BAE37442.1|/7.35968e-108/unnamed protein product [Mus musculus] 100653389 1264 0.27 0.186666667 -0.532495081 Down 0.164626349 Mir155hg Mir155 host gene (non-protein coding) - - - - gi|148665895|gb|EDK98311.1|/1.56409e-21/mCG146863 [Mus musculus] 11472 3091 1181.013333 1149.416667 -0.039123379 Down 0.164598142 Actn2 actinin alpha 2 K05699|1|0.0|1725|rno:291245|actinin alpha GO:0015629//actin cytoskeleton;GO:0031674//I band;GO:0005924//cell-substrate adherens junction;GO:0042995//cell projection GO:0010861//thyroid hormone receptor activator activity;GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0003713//transcription coactivator activity;GO:0042802//identical protein binding GO:0003012//muscle system process;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:0007044//cell-substrate junction assembly;GO:0007015//actin filament organization;GO:0030031//cell projection assembly;GO:0032413//negative regulation of ion transmembrane transporter activity;GO:0006813//potassium ion transport;GO:0051260//protein homooligomerization;GO:0006873//cellular ion homeostasis;GO:0048523//negative regulation of cellular process gi|157951643|ref|NP_150371.4|/0/alpha-actinin-2 [Mus musculus] 66880 3232 3.156666667 2.943333333 -0.100950988 Down 0.16458874 Rsrc1 arginine/serine-rich coiled-coil 1 - GO:0016604//nuclear body GO:0005488//binding "GO:0009636//response to toxic substance;GO:0000398//mRNA splicing, via spliceosome;GO:0006464//cellular protein modification process;GO:0051169//nuclear transport" "gi|148683577|gb|EDL15524.1|/1.7386e-61/arginine/serine-rich coiled-coil 1, isoform CRA_b, partial [Mus musculus]" 66646 2681 3.166666667 2.96 -0.097367837 Down 0.16458874 Rpe ribulose-5-phosphate-3-epimerase K01783|1|9e-130|467|mmu:66646|ribulose-phosphate 3-epimerase [EC:5.1.3.1] GO:0043227//membrane-bounded organelle;GO:0043227//membrane-bounded organelle;GO:0043227//membrane-bounded organelle;GO:0043227//membrane-bounded organelle "GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0030246//carbohydrate binding;GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0030246//carbohydrate binding;GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0030246//carbohydrate binding;GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0030246//carbohydrate binding;GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives" GO:0006098//pentose-phosphate shunt;GO:0006098//pentose-phosphate shunt;GO:0006098//pentose-phosphate shunt;GO:0006098//pentose-phosphate shunt gi|26325066|dbj|BAC26287.1|/1.01655e-128/unnamed protein product [Mus musculus] 105827 3035.67 2.823333333 3.033333333 0.103504576 Up 0.16458874 Amigo2 adhesion molecule with Ig like domain 2 K19511|1|2e-20|103|dan:Dana_GF10247|peroxidase [EC:1.11.1.7];K16354|2|3e-20|103|bfo:BRAFLDRAFT_89096|leucine-rich repeat and fibronectin type-III domain-containing protein 1 - - - - 68140 3007 3.206666667 2.996666667 -0.097715778 Down 0.16458874 Tigd2 tigger transposable element derived 2 K09229|1|5e-79|298|acs:100561333|KRAB and SCAN domains-containing zinc finger protein;K19326|2|1e-64|251|lcm:102349340|nesprin-1;K05164|3|2e-49|200|lcm:102357679|interleukin 17 receptor;K11496|4|2e-29|134|mdo:100031122|centromere protein B GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding - gi|124487251|ref|NP_001074614.1|/0/tigger transposable element-derived protein 2 [Mus musculus] 103172 948 1010.973333 1038.233333 0.038385769 Up 0.16455113 Chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 K00558|1|2e-12|75.9|ggo:101132302|DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37];K11837|2|6e-07|57.4|bfo:BRAFLDRAFT_121867|ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle - GO:0006796//phosphate-containing compound metabolic process "gi|34013514|ref|NP_780538.2|/3.77874e-29/coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial [Mus musculus]" 18674 1512 960.27 985.42 0.037298646 Up 0.164541728 Slc25a3 "solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3" "K15102|1|0.0|638|mmu:18674|solute carrier family 25 (mitochondrial phosphate transporter), member 3" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0051234//establishment of localization;GO:0044763 "gi|148689581|gb|EDL21528.1|/0/mCG10343, isoform CRA_c, partial [Mus musculus]" 108148 4131 20.66666667 21.38666667 0.049405926 Up 0.164513521 Galnt2 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 K00710|1|0.0|1139|mmu:108148|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0031228//intrinsic component of Golgi membrane GO:0046914//transition metal ion binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0006493//protein O-linked glycosylation;GO:0002377//immunoglobulin production gi|46877109|ref|NP_644678.2|/0/polypeptide N-acetylgalactosaminyltransferase 2 precursor [Mus musculus] 27273 3453 784.91 806.97 0.039987801 Up 0.164475911 Pdk4 "pyruvate dehydrogenase kinase, isoenzyme 4" K00898|1|0.0|806|mmu:27273|pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2] GO:0019866//organelle inner membrane;GO:0044429 GO:0032550;GO:0004672//protein kinase activity GO:0006086//acetyl-CoA biosynthetic process from pyruvate;GO:0043066//negative regulation of apoptotic process;GO:0033500//carbohydrate homeostasis;GO:0055067;GO:0070542//response to fatty acid;GO:0006796//phosphate-containing compound metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006006//glucose metabolic process;GO:0006464//cellular protein modification process;GO:0033554//cellular response to stress;GO:0019217//regulation of fatty acid metabolic process "gi|7305375|ref|NP_038771.1|/0/[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial [Mus musculus]" 21848 6157.12 5.203333333 4.936666667 -0.075898897 Down 0.164457106 Trim24 tripartite motif-containing 24 K08881|1|0.0|1787|mmu:21848|tripartite motif-containing protein 24 [EC:2.3.2.27] GO:0000790//nuclear chromatin;GO:0044444//cytoplasmic part;GO:0000790//nuclear chromatin;GO:0044444//cytoplasmic part;GO:0000790//nuclear chromatin;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0016301//kinase activity;GO:0042393//histone binding;GO:0005102//receptor binding;GO:0003712//transcription cofactor activity;GO:0044212//transcription regulatory region DNA binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0016301//kinase activity;GO:0042393//histone binding;GO:0005102//receptor binding;GO:0003712//transcription cofactor activity;GO:0044212//transcription regulatory region DNA binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0016301//kinase activity;GO:0042393//histone binding;GO:0005102//receptor binding;GO:0003712//transcription cofactor activity;GO:0044212//transcription regulatory region DNA binding;GO:0019787//ubiquitin-like protein transferase activity "GO:0006351//transcription, DNA-templated;GO:0055065//metal ion homeostasis;GO:0008283//cell proliferation;GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0009057//macromolecule catabolic process;GO:0006468//protein phosphorylation;GO:0009966//regulation of signal transduction;GO:0032446//protein modification by small protein conjugation;GO:0010608//posttranscriptional regulation of gene expression;GO:0006351//transcription, DNA-templated;GO:0055065//metal ion homeostasis;GO:0008283//cell proliferation;GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0009057//macromolecule catabolic process;GO:0006468//protein phosphorylation;GO:0009966//regulation of signal transduction;GO:0032446//protein modification by small protein conjugation;GO:0010608//posttranscriptional regulation of gene expression;GO:0006351//transcription, DNA-templated;GO:0055065//metal ion homeostasis;GO:0008283//cell proliferation;GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0009057//macromolecule catabolic process;GO:0006468//protein phosphorylation;GO:0009966//regulation of signal transduction;GO:0032446//protein modification by small protein conjugation;GO:0010608//posttranscriptional regulation of gene expression" gi|440918679|ref|NP_001258993.1|/0/transcription intermediary factor 1-alpha isoform 2 [Mus musculus] 18971 3428 4.683333333 4.953333333 0.080863985 Up 0.164457106 Pold1 "polymerase (DNA directed), delta 1, catalytic subunit" K02327|1|0.0|2088|mmu:18971|DNA polymerase delta subunit 1 [EC:2.7.7.7] - - - "gi|148690782|gb|EDL22729.1|/0/polymerase (DNA directed), delta 1, catalytic subunit, isoform CRA_a [Mus musculus]" 237926 4167 4.463333333 4.733333333 0.084734969 Up 0.164457106 Rsad1 radical S-adenosyl methionine domain containing 1 - GO:0043231//intracellular membrane-bounded organelle "GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0016634//oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor" GO:0006778//porphyrin-containing compound metabolic process;GO:0044710 "gi|148683981|gb|EDL15928.1|/0/radical S-adenosyl methionine domain containing 1, isoform CRA_a [Mus musculus]" 78925 2681 0.293333333 0.38 0.373458396 Up 0.164410094 Srd5a1 steroid 5 alpha-reductase 1 K12343|1|7e-138|494|mmu:78925|3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:1.3.1.22] GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part "GO:0035671//enone reductase activity;GO:0033765//steroid dehydrogenase activity, acting on the CH-CH group of donors;GO:0043168//anion binding" GO:0070848//response to growth factor;GO:0001501//skeletal system development;GO:0034698//response to gonadotropin;GO:0021536//diencephalon development;GO:0008207//C21-steroid hormone metabolic process;GO:0046546//development of primary male sexual characteristics;GO:0032868//response to insulin;GO:0071870//cellular response to catecholamine stimulus;GO:0014823//response to activity;GO:0071385//cellular response to glucocorticoid stimulus;GO:0006694//steroid biosynthetic process;GO:0009636//response to toxic substance;GO:0033574//response to testosterone;GO:0008406//gonad development;GO:0021543//pallium development;GO:0042430//indole-containing compound metabolic process;GO:0006721//terpenoid metabolic process;GO:0022410//circadian sleep/wake cycle process;GO:0048869//cellular developmental process;GO:0051591//response to cAMP;GO:0046545//development of primary female sexual characteristics;GO:0033554//cellular response to stress;GO:0032355//response to estradiol gi|625280786|ref|XP_007632057.1|/3.36838e-140/PREDICTED: 3-oxo-5-alpha-steroid 4-dehydrogenase 1 isoform X2 [Cricetulus griseus] 320469 5130 0.41 0.316666667 -0.372658897 Down 0.164410094 9930014A18Rik RIKEN cDNA 9930014A18 gene K10461|1|3e-07|61.2|bfo:BRAFLDRAFT_119296|kelch-like protein 24/35;K16817|2|4e-06|57.4|xma:102230685|HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4] - - - - 67922 1921 20.72 21.43333333 0.048832234 Up 0.164240851 Fam32a "family with sequence similarity 32, member A" K13120|1|3e-48|195|mmu:67922|protein FAM32A - - - gi|725603208|ref|XP_010328422.1|/2.822e-50/PREDICTED: protein FAM32A [Saimiri boliviensis boliviensis] 21824 3718 20.5 19.79333333 -0.050609317 Down 0.164240851 Thbd thrombomodulin K03907|1|0.0|1117|mmu:21824|thrombomodulin - - - - 66916 533 574.7166667 558.5933333 -0.041052532 Down 0.164231449 Ndufb7 "NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7" K03963|1|1e-57|223|mmu:66916|NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7 GO:0005746//mitochondrial respiratory chain GO:0050136//NADH dehydrogenase (quinone) activity GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy gi|13385322|ref|NP_080119.1|/9.60379e-57/NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [Mus musculus] 52538 1500 517.6466667 501.9533333 -0.044414442 Down 0.164203242 Acaa2 acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) K07508|1|0.0|758|mmu:52538|acetyl-CoA acyltransferase 2 [EC:2.3.1.16] GO:0019866//organelle inner membrane;GO:0044429 GO:0016408//C-acyltransferase activity GO:0006915//apoptotic process;GO:0006637//acyl-CoA metabolic process;GO:0009062//fatty acid catabolic process gi|20810027|gb|AAH28901.1|/0/Acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) [Mus musculus] 11950 1641 575.7733333 591.42 0.038682059 Up 0.16419384 Atp5f1 "ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1" K02127|1|1e-140|502|mmu:11950|F-type H+-transporting ATPase subunit b - - - "gi|78214312|ref|NP_033855.2|/9.12549e-140/ATP synthase F(0) complex subunit B1, mitochondrial isoform 1 [Mus musculus]" 78330 544.25 628.2033333 643.74 0.035246518 Up 0.164175035 Ndufv3 NADH dehydrogenase (ubiquinone) flavoprotein 3 K03944|1|6e-70|267|fca:101084817|NADH dehydrogenase (ubiquinone) flavoprotein 3 GO:0005746//mitochondrial respiratory chain;GO:0031981//nuclear lumen;GO:0005746//mitochondrial respiratory chain - GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy "gi|140972309|ref|NP_084363.2|/0/NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform 1 [Mus musculus]" 208691 4992 0.273333333 0.19 -0.52466199 Down 0.164165632 Eif5a2 eukaryotic translation initiation factor 5A2 K03263|1|7e-84|315|pale:102883138|translation initiation factor 5A GO:0005635//nuclear envelope;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part "GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, RNA binding" GO:0006415//translational termination;GO:0050658//RNA transport;GO:0008283//cell proliferation;GO:0006414//translational elongation;GO:0048878//chemical homeostasis;GO:0045184//establishment of protein localization;GO:0048232//male gamete generation;GO:0018205//peptidyl-lysine modification gi|431910532|gb|ELK13603.1|/7.35686e-86/Eukaryotic translation initiation factor 5A-2 [Pteropus alecto] 68949 754 9.916666667 9.483333333 -0.064461016 Down 0.164165632 Zfos1 "zinc finger, NFX1-type containing 1, antisense RNA 1" - - - - - 240776 3957 0.263333333 0.183333333 -0.522421035 Down 0.164165632 Kcnt2 "potassium channel, subfamily T, member 2" K04947|1|0.0|2222|mmu:240776|potassium channel subfamily T member 2 - GO:0032550;GO:0005267//potassium channel activity - gi|161168989|ref|NP_001074496.2|/0/potassium channel subfamily T member 2 [Mus musculus] 232339 5704 0.183333333 0.263333333 0.522421035 Up 0.164165632 Ankrd26 ankyrin repeat domain 26 K17299|1|6e-132|475|shr:100920140|POTE ankyrin domain family protein - - - gi|124487433|ref|NP_001074581.1|/0/ankyrin repeat domain-containing protein 26 [Mus musculus] 24067 4264 9.44 9.866666667 0.06377591 Up 0.164165632 Srp54a signal recognition particle 54A K03106|1|0.0|963|ptg:102957830|signal recognition particle subunit SRP54 [EC:3.6.5.4] GO:0048500//signal recognition particle;GO:0016604//nuclear body GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0003723//RNA binding;GO:0005048//signal sequence binding GO:0042221//response to chemical;GO:0010467//gene expression;GO:0009154//purine ribonucleotide catabolic process;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0019538//protein metabolic process gi|410962045|ref|XP_003987587.1|/0/PREDICTED: signal recognition particle 54 kDa protein isoform X1 [Felis catus] 17179 1844 0.193333333 0.276666667 0.517058436 Up 0.164165632 Matk megakaryocyte-associated tyrosine kinase K08888|1|0.0|975|mmu:17179|megakaryocyte-associated tyrosine kinase [EC:2.7.10.2] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0004713//protein tyrosine kinase activity;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process "gi|148699494|gb|EDL31441.1|/0/megakaryocyte-associated tyrosine kinase, isoform CRA_e, partial [Mus musculus]" 233057 2806 0.28 0.196666667 -0.509674373 Down 0.164071609 Zfp940 zinc finger protein 940 K09228|1|0.0|1215|mmu:233057|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|30424581|ref|NP_776099.1|/0/zinc finger protein 940 [Mus musculus] 104130 853 464.6266667 478.51 0.042477117 Up 0.164071609 Ndufb11 "NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11" K11351|1|3e-84|313|mmu:104130|NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11 GO:0031224//intrinsic component of membrane;GO:0005746//mitochondrial respiratory chain - GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy "gi|158631246|ref|NP_062308.2|/2.21093e-83/NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [Mus musculus]" 71876 2467 0.33 0.423333333 0.359328067 Up 0.164043401 Cenpu centromere protein U K11513|1|5e-180|634|mmu:71876|centromere protein U "GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region" GO:0005488//binding "GO:0006351//transcription, DNA-templated" gi|47523382|ref|NP_082249.1|/4.36566e-179/centromere protein U [Mus musculus] 108797 3416 0.33 0.423333333 0.359328067 Up 0.164043401 Mex3b mex3 RNA binding family member B K15686|1|0.0|721|mmu:108797|RNA-binding protein MEX3 [EC:2.3.2.27] - - - gi|50511245|dbj|BAD32608.1|/0/mKIAA2009 protein [Mus musculus] 11370 2205 519.2166667 532.4066667 0.036191942 Up 0.164024597 Acadvl "acyl-Coenzyme A dehydrogenase, very long chain" K09479|1|0.0|1217|mmu:11370|very long chain acyl-CoA dehydrogenase [EC:1.3.8.9] GO:0019866//organelle inner membrane;GO:0005759//mitochondrial matrix GO:0004466//long-chain-acyl-CoA dehydrogenase activity;GO:0000166//nucleotide binding GO:0000038//very long-chain fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006635//fatty acid beta-oxidation;GO:0019218//regulation of steroid metabolic process;GO:0048871//multicellular organismal homeostasis "gi|23956084|ref|NP_059062.1|/0/very long-chain specific acyl-CoA dehydrogenase, mitochondrial precursor [Mus musculus]" 12491 3487.06 433.1733333 445.4433333 0.040297481 Up 0.16395878 Cd36 CD36 antigen K06259|1|0.0|920|mmu:12491|CD36 antigen GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459 GO:0036041//long-chain fatty acid binding;GO:0030228//lipoprotein particle receptor activity;GO:0071813//lipoprotein particle binding;GO:0019838//growth factor binding;GO:0008329//signaling pattern recognition receptor activity;GO:0036041//long-chain fatty acid binding;GO:0030228//lipoprotein particle receptor activity;GO:0071813//lipoprotein particle binding;GO:0019838//growth factor binding;GO:0008329//signaling pattern recognition receptor activity;GO:0036041//long-chain fatty acid binding;GO:0030228//lipoprotein particle receptor activity;GO:0071813//lipoprotein particle binding;GO:0019838//growth factor binding;GO:0008329//signaling pattern recognition receptor activity;GO:0036041//long-chain fatty acid binding;GO:0030228//lipoprotein particle receptor activity;GO:0071813//lipoprotein particle binding;GO:0019838//growth factor binding;GO:0008329//signaling pattern recognition receptor activity;GO:0036041//long-chain fatty acid binding;GO:0030228//lipoprotein particle receptor activity;GO:0071813//lipoprotein particle binding;GO:0019838//growth factor binding;GO:0008329//signaling pattern recognition receptor activity "GO:0010467//gene expression;GO:0001952//regulation of cell-matrix adhesion;GO:0006639//acylglycerol metabolic process;GO:0032868//response to insulin;GO:0070339;GO:0002758//innate immune response-activating signal transduction;GO:0090322//regulation of superoxide metabolic process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0050663//cytokine secretion;GO:0006911//phagocytosis, engulfment;GO:0051094//positive regulation of developmental process;GO:0031667//response to nutrient levels;GO:0007596//blood coagulation;GO:0010742//macrophage derived foam cell differentiation;GO:0015918//sterol transport;GO:0033194//response to hydroperoxide;GO:0042742//defense response to bacterium;GO:0001934//positive regulation of protein phosphorylation;GO:0070391;GO:0001819//positive regulation of cytokine production;GO:0003073//regulation of systemic arterial blood pressure;GO:0010878//cholesterol storage;GO:0043627//response to estrogen;GO:0042308//negative regulation of protein import into nucleus;GO:0034381//plasma lipoprotein particle clearance;GO:0001525//angiogenesis;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0055095;GO:0010934//macrophage cytokine production;GO:0044126;GO:0000165//MAPK cascade;GO:0015909//long-chain fatty acid transport;GO:0034599//cellular response to oxidative stress;GO:0032496//response to lipopolysaccharide;GO:0006631//fatty acid metabolic process;GO:0010467//gene expression;GO:0001952//regulation of cell-matrix adhesion;GO:0006639//acylglycerol metabolic process;GO:0032868//response to insulin;GO:0070339;GO:0002758//innate immune response-activating signal transduction;GO:0090322//regulation of superoxide metabolic process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0050663//cytokine secretion;GO:0006911//phagocytosis, engulfment;GO:0051094//positive regulation of developmental process;GO:0031667//response to nutrient levels;GO:0007596//blood coagulation;GO:0010742//macrophage derived foam cell differentiation;GO:0015918//sterol transport;GO:0033194//response to hydroperoxide;GO:0042742//defense response to bacterium;GO:0001934//positive regulation of protein phosphorylation;GO:0070391;GO:0001819//positive regulation of cytokine production;GO:0003073//regulation of systemic arterial blood pressure;GO:0010878//cholesterol storage;GO:0043627//response to estrogen;GO:0042308//negative regulation of protein import into nucleus;GO:0034381//plasma lipoprotein particle clearance;GO:0001525//angiogenesis;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0055095;GO:0010934//macrophage cytokine production;GO:0044126;GO:0000165//MAPK cascade;GO:0015909//long-chain fatty acid transport;GO:0034599//cellular response to oxidative stress;GO:0032496//response to lipopolysaccharide;GO:0006631//fatty acid metabolic process;GO:0010467//gene expression;GO:0001952//regulation of cell-matrix adhesion;GO:0006639//acylglycerol metabolic process;GO:0032868//response to insulin;GO:0070339;GO:0002758//innate immune response-activating signal transduction;GO:0090322//regulation of superoxide metabolic process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0050663//cytokine secretion;GO:0006911//phagocytosis, engulfment;GO:0051094//positive regulation of developmental process;GO:0031667//response to nutrient levels;GO:0007596//blood coagulation;GO:0010742//macrophage derived foam cell differentiation;GO:0015918//sterol transport;GO:0033194//response to hydroperoxide;GO:0042742//defense response to bacterium;GO:0001934//positive regulation of protein phosphorylation;GO:0070391;GO:0001819//positive regulation of cytokine production;GO:0003073//regulation of systemic arterial blood pressure;GO:0010878//cholesterol storage;GO:0043627//response to estrogen;GO:0042308//negative regulation of protein import into nucleus;GO:0034381//plasma lipoprotein particle clearance;GO:0001525//angiogenesis;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0055095;GO:0010934//macrophage cytokine production;GO:0044126;GO:0000165//MAPK cascade;GO:0015909//long-chain fatty acid transport;GO:0034599//cellular response to oxidative stress;GO:0032496//response to lipopolysaccharide;GO:0006631//fatty acid metabolic process;GO:0010467//gene expression;GO:0001952//regulation of cell-matrix adhesion;GO:0006639//acylglycerol metabolic process;GO:0032868//response to insulin;GO:0070339;GO:0002758//innate immune response-activating signal transduction;GO:0090322//regulation of superoxide metabolic process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0050663//cytokine secretion;GO:0006911//phagocytosis, engulfment;GO:0051094//positive regulation of developmental process;GO:0031667//response to nutrient levels;GO:0007596//blood coagulation;GO:0010742//macrophage derived foam cell differentiation;GO:0015918//sterol transport;GO:0033194//response to hydroperoxide;GO:0042742//defense response to bacterium;GO:0001934//positive regulation of protein phosphorylation;GO:0070391;GO:0001819//positive regulation of cytokine production;GO:0003073//regulation of systemic arterial blood pressure;GO:0010878//cholesterol storage;GO:0043627//response to estrogen;GO:0042308//negative regulation of protein import into nucleus;GO:0034381//plasma lipoprotein particle clearance;GO:0001525//angiogenesis;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0055095;GO:0010934//macrophage cytokine production;GO:0044126;GO:0000165//MAPK cascade;GO:0015909//long-chain fatty acid transport;GO:0034599//cellular response to oxidative stress;GO:0032496//response to lipopolysaccharide;GO:0006631//fatty acid metabolic process;GO:0010467//gene expression;GO:0001952//regulation of cell-matrix adhesion;GO:0006639//acylglycerol metabolic process;GO:0032868//response to insulin;GO:0070339;GO:0002758//innate immune response-activating signal transduction;GO:0090322//regulation of superoxide metabolic process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0050663//cytokine secretion;GO:0006911//phagocytosis, engulfment;GO:0051094//positive regulation of developmental process;GO:0031667//response to nutrient levels;GO:0007596//blood coagulation;GO:0010742//macrophage derived foam cell differentiation;GO:0015918//sterol transport;GO:0033194//response to hydroperoxide;GO:0042742//defense response to bacterium;GO:0001934//positive regulation of protein phosphorylation;GO:0070391;GO:0001819//positive regulation of cytokine production;GO:0003073//regulation of systemic arterial blood pressure;GO:0010878//cholesterol storage;GO:0043627//response to estrogen;GO:0042308//negative regulation of protein import into nucleus;GO:0034381//plasma lipoprotein particle clearance;GO:0001525//angiogenesis;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0055095;GO:0010934//macrophage cytokine production;GO:0044126;GO:0000165//MAPK cascade;GO:0015909//long-chain fatty acid transport;GO:0034599//cellular response to oxidative stress;GO:0032496//response to lipopolysaccharide;GO:0006631//fatty acid metabolic process" gi|227116343|ref|NP_031669.3|/0/platelet glycoprotein 4 [Mus musculus] 100503572 2420.03 7.08 6.753333333 -0.068149592 Down 0.163855354 Bbip1 BBSome interacting protein 1 K19399|1|5e-15|85.9|mmu:100503572|BBSome-interacting protein 1 GO:0044424;GO:0043234//protein complex;GO:0044424;GO:0043234//protein complex - GO:0010927;GO:0010927 gi|569006132|ref|XP_006526610.1|/1.83747e-19/PREDICTED: BBSome-interacting protein 1 isoform X2 [Mus musculus] 74112 2926 7.296666667 6.97 -0.066078893 Down 0.163855354 Usp16 ubiquitin specific peptidase 16 K11844|1|0.0|1517|mmu:74112|ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle GO:0032182//ubiquitin-like protein binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0016790//thiolester hydrolase activity "GO:0006351//transcription, DNA-templated;GO:0006414//translational elongation;GO:0016578//histone deubiquitination;GO:0019941//modification-dependent protein catabolic process;GO:0033554//cellular response to stress;GO:0000087//mitotic M phase;GO:0051260//protein homooligomerization" gi|251823802|ref|NP_077220.2|/0/ubiquitin carboxyl-terminal hydrolase 16 [Mus musculus] 67456 3935 6.886666667 7.213333333 0.066860245 Up 0.163855354 Ergic2 ERGIC and golgi 2 K20366|1|0.0|628|mmu:67456|endoplasmic reticulum-Golgi intermediate compartment protein 2 - - - - 17260 6365.47 6.41 6.736666667 0.071710559 Up 0.163855354 Mef2c myocyte enhancer factor 2C K04454|1|0.0|870|cge:100774573|MADS-box transcription enhancer factor 2C GO:0016604//nuclear body;GO:0032991//macromolecular complex;GO:0030016//myofibril;GO:0016604//nuclear body;GO:0032991//macromolecular complex;GO:0000785//chromatin "GO:0003723//RNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0008134//transcription factor binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003723//RNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0019904//protein domain specific binding;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding" GO:0030219//megakaryocyte differentiation;GO:0048562//embryonic organ morphogenesis;GO:0001944//vasculature development;GO:0071363//cellular response to growth factor stimulus;GO:0003143//embryonic heart tube morphogenesis;GO:0002573//myeloid leukocyte differentiation;GO:0003299;GO:0055007//cardiac muscle cell differentiation;GO:0003207//cardiac chamber formation;GO:0030282//bone mineralization;GO:0050851//antigen receptor-mediated signaling pathway;GO:0048771//tissue remodeling;GO:0043066//negative regulation of apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0050931//pigment cell differentiation;GO:0001709//cell fate determination;GO:0030182//neuron differentiation;GO:0003128//heart field specification;GO:0048762//mesenchymal cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0030888//regulation of B cell proliferation;GO:0051592//response to calcium ion;GO:0035983;GO:0032496//response to lipopolysaccharide;GO:0035850;GO:0032526//response to retinoic acid;GO:0001649//osteoblast differentiation;GO:0032870//cellular response to hormone stimulus;GO:2000108//positive regulation of leukocyte apoptotic process;GO:0051239;GO:0022603//regulation of anatomical structure morphogenesis;GO:0051155//positive regulation of striated muscle cell differentiation;GO:0003172;GO:0050803//regulation of synapse structure or activity;GO:0032092//positive regulation of protein binding;GO:0045445//myoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0002260//lymphocyte homeostasis;GO:0050673//epithelial cell proliferation;GO:0033554//cellular response to stress;GO:0002467//germinal center formation;GO:0042493//response to drug;GO:0036075;GO:0010692;GO:0035914//skeletal muscle cell differentiation;GO:0001662//behavioral fear response;GO:0030219//megakaryocyte differentiation;GO:0001678//cellular glucose homeostasis;GO:0021766//hippocampus development;GO:0055003//cardiac myofibril assembly;GO:0048562//embryonic organ morphogenesis;GO:0001944//vasculature development;GO:0071363//cellular response to growth factor stimulus;GO:0003143//embryonic heart tube morphogenesis;GO:0002573//myeloid leukocyte differentiation;GO:0003299;GO:0003207//cardiac chamber formation;GO:0030282//bone mineralization;GO:0050851//antigen receptor-mediated signaling pathway;GO:0000165//MAPK cascade;GO:0048771//tissue remodeling;GO:0043066//negative regulation of apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0050931//pigment cell differentiation;GO:0001709//cell fate determination;GO:0030182//neuron differentiation;GO:0003128//heart field specification;GO:0048762//mesenchymal cell differentiation;GO:0007005//mitochondrion organization;GO:0008285//negative regulation of cell proliferation;GO:0003300//cardiac muscle hypertrophy;GO:0030888//regulation of B cell proliferation;GO:0051592//response to calcium ion;GO:0035983;GO:0032496//response to lipopolysaccharide;GO:0008016//regulation of heart contraction;GO:0035850;GO:0032526//response to retinoic acid;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001649//osteoblast differentiation;GO:0032870//cellular response to hormone stimulus;GO:2000108//positive regulation of leukocyte apoptotic process;GO:0022603//regulation of anatomical structure morphogenesis;GO:0051155//positive regulation of striated muscle cell differentiation;GO:0003172;GO:0009991//response to extracellular stimulus;GO:0050803//regulation of synapse structure or activity;GO:0032092//positive regulation of protein binding;GO:0045445//myoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0002260//lymphocyte homeostasis;GO:0050673//epithelial cell proliferation;GO:0033554//cellular response to stress;GO:0002467//germinal center formation;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0042493//response to drug;GO:0036075;GO:0010692;GO:0035914//skeletal muscle cell differentiation;GO:0001662//behavioral fear response gi|13384624|ref|NP_079558.1|/0/myocyte-specific enhancer factor 2C isoform 2 [Mus musculus] 224598 2988 0.726666667 0.613333333 -0.244622369 Down 0.163798939 Zfp758 zinc finger protein 758 K09228|1|0.0|877|mmu:240038|KRAB domain-containing zinc finger protein - - - gi|114842387|ref|NP_663459.2|/0/zinc finger protein 758 [Mus musculus] 76498 2507 20.5 21.18666667 0.047532714 Up 0.163789537 Paqr4 progestin and adipoQ receptor family member IV K06633|1|2e-23|114|amj:102575481|membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1];K07297|2|9e-15|85.1|dpo:Dpse_GA18798|adiponectin receptor GO:0031224//intrinsic component of membrane - - gi|12963841|ref|NP_076313.1|/8.74582e-151/progestin and adipoQ receptor family member 4 [Mus musculus] 17995 1608 395.5266667 406.26 0.03862836 Up 0.163751927 Ndufv1 NADH dehydrogenase (ubiquinone) flavoprotein 1 K03942|1|0.0|960|mmu:17995|NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3] - - - - 74737 5804 2.52 2.33 -0.113093779 Down 0.163733123 Pcf11 PCF11 cleavage and polyadenylation factor subunit K14400|1|0.0|2521|mmu:74737|pre-mRNA cleavage complex 2 protein Pcf11 - - - gi|50510655|dbj|BAD32313.1|/0/mKIAA0824 protein [Mus musculus] 75739 4975 2.48 2.293333333 -0.112894056 Down 0.163733123 Mpp7 "membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)" K06091|1|1e-54|217|cfa:490740|MAGUK p55 subfamily member 5 GO:0043296//apical junction complex;GO:0043234//protein complex;GO:0043296//apical junction complex;GO:0043234//protein complex GO:0046983//protein dimerization activity;GO:0046983//protein dimerization activity GO:0006461//protein complex assembly;GO:0008104//protein localization;GO:0007043//cell-cell junction assembly;GO:0006461//protein complex assembly;GO:0008104//protein localization;GO:0007043//cell-cell junction assembly "gi|148691076|gb|EDL23023.1|/0/mCG5292, isoform CRA_c, partial [Mus musculus]" 66315 3429.97 2.45 2.643333333 0.109576616 Up 0.163733123 Senp7 SUMO1/sentrin specific peptidase 7 K08596|1|0.0|1895|mmu:66315|sentrin-specific protease 7 [EC:3.4.22.68] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process gi|51593102|ref|NP_001003973.1|/1.97825e-105/sentrin-specific protease 7 isoform 4 [Mus musculus] 67534 4341 0.79 0.913333333 0.209288834 Up 0.163648501 Ttll4 "tubulin tyrosine ligase-like family, member 4" K16601|1|0.0|2216|mmu:67534|tubulin polyglutamylase TTLL4 [EC:6.-.-.-] - - - gi|62510079|ref|NP_001014974.1|/0/tubulin polyglutamylase TTLL4 [Mus musculus] 76365 4679 0.916666667 0.793333333 -0.208470045 Down 0.163648501 Tbx18 T-box18 K10183|1|0.0|1083|fca:101083679|T-box protein 18 GO:0017053//transcriptional repressor complex GO:0001104//RNA polymerase II transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0008134//transcription factor binding "GO:0006351//transcription, DNA-templated;GO:0060827//regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation;GO:0016337//single organismal cell-cell adhesion;GO:0003161//cardiac conduction system development;GO:0050954//sensory perception of mechanical stimulus;GO:0002009//morphogenesis of an epithelium;GO:0009798//axis specification;GO:0042692//muscle cell differentiation;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0048598//embryonic morphogenesis" gi|755730439|ref|XP_003986395.3|/0/PREDICTED: T-box transcription factor TBX18 [Felis catus] 621080 1974 0.92 0.796666667 -0.207657649 Down 0.163648501 AI429214 expressed sequence AI429214 - - - - gi|85986611|ref|NP_001034309.1|/3.57544e-157/uncharacterized protein C8orf48 homolog [Mus musculus] 69226 1948 3.646666667 3.88 0.08947832 Up 0.163620294 Snx24 sorting nexing 24 K17941|1|9e-94|347|rno:361328|sorting nexin-22/24 GO:0012506//vesicle membrane GO:0005543//phospholipid binding GO:0044763;GO:0045184//establishment of protein localization gi|569004455|ref|XP_006526283.1|/5.69893e-99/PREDICTED: sorting nexin-24 isoform X1 [Mus musculus] 78796 2685.82 3.886666667 3.653333333 -0.08931999 Down 0.163620294 Zcchc4 "zinc finger, CCHC domain containing 4" K02367|1|7e-43|178|smm:Smp_146320.1|glucuronyl/N-acetylglucosaminyl transferase EXT2 [EC:2.4.1.224 2.4.1.225] - GO:0016741;GO:0046914//transition metal ion binding;GO:0016741;GO:0046914//transition metal ion binding GO:0008152//metabolic process;GO:0008152//metabolic process "gi|148705718|gb|EDL37665.1|/0/mCG18787, isoform CRA_c, partial [Mus musculus]" 17690 1551 0.16 0.09 -0.830074999 Down 0.163610892 Msi1 musashi RNA-binding protein 1 K14411|1|0.0|679|mmu:17690|RNA-binding protein Musashi GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex GO:0036094//small molecule binding;GO:0008187//poly-pyrimidine tract binding GO:0030154//cell differentiation;GO:0048731//system development;GO:0009719 gi|6678940|ref|NP_032655.1|/0/RNA-binding protein Musashi homolog 1 [Mus musculus] 68349 940 380.7 390.0733333 0.035090805 Up 0.163573282 Ndufs3 NADH dehydrogenase (ubiquinone) Fe-S protein 3 K03936|1|6e-152|538|mmu:68349|NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:1.6.5.3 1.6.99.3] GO:0005746//mitochondrial respiratory chain GO:0050136//NADH dehydrogenase (quinone) activity GO:0012502//induction of programmed cell death;GO:0016049//cell growth;GO:0044710;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization "gi|58037117|ref|NP_080964.1|/5.00472e-151/NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial precursor [Mus musculus]" 71927 3355 18.34 19.02 0.052523607 Up 0.163516868 Itfg1 integrin alpha FG-GAP repeat containing 1 K17257|1|0.0|1134|mmu:71927|integrin alpha FG-GAP repeat containing protein 1 - - - - 15507 913 328.6533333 320.4633333 -0.036407321 Down 0.163451051 Hspb1 heat shock protein 1 K04455|1|1e-118|428|mmu:15507|heat shock protein beta-1 - - - - 626316 2847 0.033333333 0.093333333 1.485426827 Up 0.163422844 Gm13051 zinc finger protein 987 K09228|1|0.0|1366|mmu:626316|KRAB domain-containing zinc finger protein - - - gi|755502575|ref|XP_011246455.1|/0/PREDICTED: LOW QUALITY PROTEIN: gastrula zinc finger protein XlCGF26.1-like [Mus musculus] 104360 1868 0.086666667 0.03 -1.530514717 Down 0.163422844 Isl2 insulin related protein 2 (islet 2) K18492|1|0.0|707|mmu:104360|insulin gene enhancer protein ISL-2 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0007411//axon guidance;GO:0021522//spinal cord motor neuron differentiation;GO:0006351//transcription, DNA-templated" gi|154146254|ref|NP_081673.2|/0/insulin gene enhancer protein ISL-2 [Mus musculus] 56363 3339 0.09 0.033333333 -1.432959407 Down 0.163422844 Tmeff2 transmembrane protein with EGF-like and two follistatin-like domains 2 K06254|1|5e-29|132|cin:100187262|agrin GO:0031224//intrinsic component of membrane - - gi|724945729|ref|XP_010387068.1|/0/PREDICTED: tomoregulin-2 isoform X1 [Rhinopithecus roxellana] 106565 1415 0.036666667 0.1 1.447458977 Up 0.163422844 Dlk2 delta-like 2 homolog (Drosophila) K06051|1|1e-66|256|chx:102182594|delta GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity GO:0007219//Notch signaling pathway;GO:0045444//fat cell differentiation;GO:0007219//Notch signaling pathway;GO:0045444//fat cell differentiation gi|112818475|gb|AAI22519.1|/0/Dlk2 protein [Mus musculus] 27007 3179 0.096666667 0.033333333 -1.5360529 Down 0.163422844 Klrk1 "killer cell lectin-like receptor subfamily K, member 1" K06728|1|5e-136|488|mmu:27007|killer cell lectin-like receptor subfamily K member 1 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0042287//MHC protein binding;GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0042287//MHC protein binding;GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0042287//MHC protein binding;GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity GO:0032496//response to lipopolysaccharide;GO:0002220;GO:0046649//lymphocyte activation;GO:0042742//defense response to bacterium;GO:0006809//nitric oxide biosynthetic process;GO:0001819//positive regulation of cytokine production;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0032496//response to lipopolysaccharide;GO:0002220;GO:0046649//lymphocyte activation;GO:0042742//defense response to bacterium;GO:0006809//nitric oxide biosynthetic process;GO:0001819//positive regulation of cytokine production;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0032496//response to lipopolysaccharide;GO:0002220;GO:0046649//lymphocyte activation;GO:0042742//defense response to bacterium;GO:0006809//nitric oxide biosynthetic process;GO:0001819//positive regulation of cytokine production;GO:0001912//positive regulation of leukocyte mediated cytotoxicity gi|14861840|ref|NP_149069.1|/4.11414e-135/NKG2-D type II integral membrane protein isoform a [Mus musculus] 329954 1511 0.1 0.036666667 -1.447458977 Down 0.163422844 Catsper4 "cation channel, sperm associated 4" K16892|1|0.0|822|mmu:329954|cation channel sperm-associated protein 4 GO:0030141//secretory granule;GO:0005929//cilium;GO:0005891//voltage-gated calcium channel complex;GO:0030141//secretory granule;GO:0005929//cilium;GO:0005891//voltage-gated calcium channel complex GO:0005488//binding;GO:0005261//cation channel activity;GO:0005488//binding;GO:0005261//cation channel activity GO:0048869//cellular developmental process;GO:0048870//cell motility;GO:0048232//male gamete generation;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0048869//cellular developmental process;GO:0048870//cell motility;GO:0048232//male gamete generation;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport gi|194097451|ref|NP_001123502.1|/0/cation channel sperm-associated protein 4 isoform 2 [Mus musculus] 17922 6591 0.086666667 0.03 -1.530514717 Down 0.163422844 Myo7b myosin VIIB K10359|1|0.0|4244|mmu:17922|myosin VII GO:0044459;GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 - "gi|148664634|gb|EDK97050.1|/0/myosin VIIb, isoform CRA_b, partial [Mus musculus]" 277773 1656 0.093333333 0.033333333 -1.485426827 Down 0.163422844 Fam205c "family with sequence similarity 205, member C" - GO:0031224//intrinsic component of membrane - - gi|29244306|ref|NP_808453.1|/2.40351e-180/protein FAM205C [Mus musculus] 213272 1727 0.09 0.033333333 -1.432959407 Down 0.163422844 Txndc2 thioredoxin domain containing 2 (spermatozoa) K03671|1|1e-31|140|oaa:100076650|thioredoxin 1 GO:0031981//nuclear lumen;GO:0005929//cilium;GO:0031981//nuclear lumen;GO:0005929//cilium "GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups;GO:0016209//antioxidant activity;GO:0015036//disulfide oxidoreductase activity;GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups;GO:0016209//antioxidant activity;GO:0015036//disulfide oxidoreductase activity" GO:0048869//cellular developmental process;GO:0019725//cellular homeostasis;GO:0048232//male gamete generation;GO:0018904;GO:0048869//cellular developmental process;GO:0019725//cellular homeostasis;GO:0048232//male gamete generation;GO:0018904 gi|225579134|ref|NP_001139474.1|/0/thioredoxin domain-containing protein 2 isoform 1 [Mus musculus] 71901 2109 9.753333333 10.17333333 0.060825193 Up 0.163394637 Fam219a "family with sequence similarity 219, member A" - - - - gi|227430293|ref|NP_082269.2|/4.80366e-59/protein FAM219A isoform 2 [Mus musculus] 77974 1658 0.153333333 0.086666667 -0.823122238 Down 0.163338223 Rdh12 retinol dehydrogenase 12 K11153|1|1e-168|595|mmu:77974|retinol dehydrogenase 12 [EC:1.1.1.300] - - - - 234479 2642 0.153333333 0.086666667 -0.823122238 Down 0.163338223 Gm4890 predicted gene 4890 - - - - - 69632 10483 18.98333333 18.31333333 -0.051838932 Down 0.163263003 Arhgef12 Rho guanine nucleotide exchange factor (GEF) 12 K07532|1|0.0|2836|mmu:69632|Rho guanine nucleotide exchange factor 12 GO:0044424 GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding GO:0007266//Rho protein signal transduction;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway "gi|148693599|gb|EDL25546.1|/0/Rho guanine nucleotide exchange factor (GEF) 12, isoform CRA_b, partial [Mus musculus]" 231672 4978 21.71333333 21.04 -0.045446514 Down 0.163263003 Fbxw8 F-box and WD-40 domain protein 8 K10264|1|0.0|1045|mmu:231672|F-box and WD-40 domain protein 8 - - - gi|120407054|ref|NP_766309.2|/0/F-box/WD repeat-containing protein 8 [Mus musculus] 75339 2954 4.523333333 4.783333333 0.080630016 Up 0.163225394 Mphosph8 M-phase phosphoprotein 8 K16726|1|2e-16|91.3|dsi:Dsimw501_GD21081|ankyrin repeat domain-containing protein 17 GO:0000786//nucleosome;GO:0000790//nuclear chromatin;GO:0016020//membrane "GO:0042393//histone binding;GO:0016763//transferase activity, transferring pentosyl groups" "GO:0006486//protein glycosylation;GO:0006351//transcription, DNA-templated;GO:0006306//DNA methylation" gi|74197166|dbj|BAE35129.1|/0/unnamed protein product [Mus musculus] 108655 6887.85 5.026666667 4.77 -0.075612757 Down 0.163225394 Foxp1 forkhead box P1 K09409|1|0.0|925|mmu:108655|forkhead box protein P - - - gi|16716509|ref|NP_444432.1|/0/forkhead box protein P1 isoform 1 [Mus musculus] 12159 1986.36 4.576666667 4.833333333 0.078721275 Up 0.163225394 Bmp4 bone morphogenetic protein 4 K04662|1|0.0|754|hgl:101711207|bone morphogenetic protein 2/4 - - - - 18141 4766 4.653333333 4.91 0.077458489 Up 0.163225394 Nup50 nucleoporin 50 K14295|1|0.0|669|mmu:18141|nuclear pore complex protein Nup50 GO:0005635//nuclear envelope;GO:0032991//macromolecular complex GO:0005488//binding;GO:0005215//transporter activity GO:0051169//nuclear transport gi|38016154|ref|NP_057923.2|/0/nuclear pore complex protein Nup50 [Mus musculus] 11435 4320 0.46 0.56 0.283792966 Up 0.163150175 Chrna1 "cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)" K04803|1|0.0|826|mmu:11435|nicotinic acetylcholine receptor alpha-1 GO:0097060//synaptic membrane;GO:0005887//integral component of plasma membrane GO:0004888//transmembrane signaling receptor activity;GO:0042165//neurotransmitter binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0001508//action potential;GO:0006941//striated muscle contraction;GO:0048741//skeletal muscle fiber development;GO:0006811//ion transport;GO:0050879//multicellular organismal movement;GO:0007268//chemical synaptic transmission gi|2073544|gb|AAB53942.1|/0/acetylcholine receptor alpha-subunit [Mus musculus] 12861 533 213.0366667 219.51 0.043184904 Up 0.163140772 Cox6a1 cytochrome c oxidase subunit VIa polypeptide 1 K02266|1|2e-47|190|mmu:12861|cytochrome c oxidase subunit 6a GO:0005746//mitochondrial respiratory chain GO:0015002//heme-copper terminal oxidase activity GO:0022900//electron transport chain gi|475707|gb|AAA17836.1|/1.17671e-46/cytochrome c oxidase subunit VIaL [Mus musculus] 18211 2606 0.103333333 0.04 -1.36923381 Down 0.163121968 Ntrk1 "neurotrophic tyrosine kinase, receptor, type 1" K03176|1|0.0|1477|mmu:18211|neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1] GO:0043005//neuron projection;GO:0031982//vesicle;GO:0016021//integral component of membrane;GO:0005769//early endosome;GO:0044297//cell body GO:0004713//protein tyrosine kinase activity;GO:0005165//neurotrophin receptor binding;GO:0005030//neurotrophin receptor activity;GO:0032550;GO:0043121//neurotrophin binding;GO:0042802//identical protein binding "GO:0030098//lymphocyte differentiation;GO:0009628//response to abiotic stimulus;GO:0003006//developmental process involved in reproduction;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0019233//sensory perception of pain;GO:0043410//positive regulation of MAPK cascade;GO:0035249//synaptic transmission, glutamatergic;GO:0007409//axonogenesis;GO:0021545//cranial nerve development;GO:0006935//chemotaxis;GO:0010975//regulation of neuron projection development;GO:0044708//single-organism behavior;GO:0070848//response to growth factor;GO:0009991//response to extracellular stimulus;GO:0008283//cell proliferation;GO:0048483//autonomic nervous system development;GO:0001525//angiogenesis;GO:0035094//response to nicotine;GO:0043066//negative regulation of apoptotic process;GO:0097305//response to alcohol;GO:0006468//protein phosphorylation;GO:0009611//response to wounding" gi|169234626|ref|NP_001028296.1|/0/high affinity nerve growth factor receptor precursor [Mus musculus] 546144 5234 0.093333333 0.036666667 -1.347923303 Down 0.163121968 Wdr72 WD repeat domain 72 K18643|1|1e-06|59.3|ccw:104691807|katanin p80 WD40 repeat-containing subunit B1 - - - gi|148226059|ref|NP_001028672.2|/0/WD repeat-containing protein 72 [Mus musculus] 11740 1317 234.8666667 228.5066667 -0.039605718 Down 0.163121968 Slc25a5 "solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5" "K05863|1|4e-162|573|mmu:11740|solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31" GO:0005759//mitochondrial matrix;GO:0016021//integral component of membrane;GO:0005819//spindle;GO:0019866//organelle inner membrane GO:0005345//purine nucleobase transmembrane transporter activity;GO:0005488//binding GO:0015980//energy derivation by oxidation of organic compounds;GO:0010823//negative regulation of mitochondrion organization;GO:0008283//cell proliferation;GO:0006863//purine nucleobase transport;GO:0030073//insulin secretion "gi|45829841|gb|AAH68199.1|/4.63358e-165/SLC25A5 protein, partial [Homo sapiens]" 93880 3055 0.096666667 0.036666667 -1.398549376 Down 0.163121968 Pcdhb9 protocadherin beta 9 K16494|1|0.0|1538|mmu:93880|protocadherin beta GO:0031224//intrinsic component of membrane - GO:0016337//single organismal cell-cell adhesion gi|113866011|ref|NP_444364.3|/0/protocadherin beta 9 [Mus musculus] 320825 2495 0.1 0.04 -1.321928095 Down 0.163121968 Samd5 sterile alpha motif domain containing 5 "K14079|1|1e-20|104|dgr:Dgri_GH21064|poly(A) RNA polymerase GLD2 [EC:2.7.7.19];K15909|2|3e-07|60.1|cmy:102929354|phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86];K18439|3|1e-06|58.2|mze:101481967|Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1" - - - gi|110556634|ref|NP_796245.2|/3.15034e-84/sterile alpha motif domain-containing protein 5 [Mus musculus] 12840 2746 0.04 0.1 1.321928095 Up 0.163121968 Col9a2 "collagen, type IX, alpha 2" "K08131|1|1e-154|549|mmu:12840|collagen, type IX, alpha" - - - gi|227116289|ref|NP_031767.2|/1.22628e-153/collagen alpha-2(IX) chain precursor [Mus musculus] 67068 712.6 224.5466667 230.66 0.038752534 Up 0.163027944 Dynlrb1 dynein light chain roadblock-type 1 K10419|1|1e-46|188|tup:102476348|dynein light chain roadblock-type - - - - 11733 3013.07 197.5566667 203.6333333 0.043707208 Up 0.163018542 Ank1 "ankyrin 1, erythroid" K10380|1|0.0|3516|mmu:11733|ankyrin GO:0097060//synaptic membrane;GO:0031672//A band;GO:0032589//neuron projection membrane;GO:0031674//I band;GO:0005856//cytoskeleton;GO:0005783//endoplasmic reticulum;GO:0043005//neuron projection;GO:0031672//A band;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0097060//synaptic membrane;GO:0031672//A band;GO:0032589//neuron projection membrane;GO:0031674//I band;GO:0005856//cytoskeleton;GO:0005783//endoplasmic reticulum "GO:0030674//protein binding, bridging;GO:0008092//cytoskeletal protein binding;GO:0019899//enzyme binding;GO:0008092//cytoskeletal protein binding;GO:0019899//enzyme binding;GO:0030674//protein binding, bridging;GO:0008092//cytoskeletal protein binding;GO:0019899//enzyme binding" GO:0016482//cytosolic transport;GO:0006778//porphyrin-containing compound metabolic process;GO:0006612//protein targeting to membrane;GO:0007154//cell communication;GO:0006996//organelle organization;GO:0006812//cation transport;GO:0030218//erythrocyte differentiation;GO:0006778//porphyrin-containing compound metabolic process;GO:0006812//cation transport;GO:0030218//erythrocyte differentiation;GO:0016043//cellular component organization;GO:0046907//intracellular transport;GO:0016482//cytosolic transport;GO:0006778//porphyrin-containing compound metabolic process;GO:0006612//protein targeting to membrane;GO:0007154//cell communication;GO:0006996//organelle organization;GO:0006812//cation transport;GO:0030218//erythrocyte differentiation gi|160707915|ref|NP_001104253.1|/0/ankyrin-1 isoform 1 [Mus musculus] 17022 2075 18.07666667 17.41666667 -0.053660133 Down 0.16297153 Lum lumican K08122|1|0.0|646|mmu:17022|lumican GO:0005581//collagen trimer GO:0005515//protein binding GO:0050953//sensory perception of light stimulus;GO:0001501//skeletal system development;GO:0030198//extracellular matrix organization;GO:0010033//response to organic substance;GO:0006366//transcription from RNA polymerase II promoter gi|160333372|ref|NP_032550.2|/0/lumican precursor [Mus musculus] 83669 4169 6.026666667 6.343333333 0.073880884 Up 0.162886908 Wdr6 WD repeat domain 6 K06711|1|1e-146|524|fch:102046917|hypoxia-inducible factor prolyl 4-hydroxylase [EC:1.14.11.-];K09008|2|1e-103|380|phi:102108507|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3;K03130|3|5e-06|57.0|hmg:100208823|transcription initiation factor TFIID subunit 5 GO:0043234//protein complex;GO:0044424 GO:0005515//protein binding GO:0022402//cell cycle process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008283//cell proliferation;GO:0006914//autophagy gi|13878227|ref|NP_113569.1|/0/WD repeat-containing protein 6 [Mus musculus] 23972 3603.63 6.653333333 6.33 -0.071871815 Down 0.162886908 Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 K13811|1|0.0|1251|mmu:23972|3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25] - GO:0016301//kinase activity;GO:0032550;GO:0004779//sulfate adenylyltransferase activity;GO:0016301//kinase activity;GO:0032550;GO:0004779//sulfate adenylyltransferase activity GO:0006790//sulfur compound metabolic process;GO:0007599//hemostasis;GO:0006796//phosphate-containing compound metabolic process;GO:0001501//skeletal system development;GO:0006790//sulfur compound metabolic process;GO:0007599//hemostasis;GO:0006796//phosphate-containing compound metabolic process;GO:0001501//skeletal system development gi|61098088|ref|NP_035994.2|/0/bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 isoform 1 [Mus musculus] 74168 1838 6.706666667 7.03 0.06792879 Up 0.162886908 Zdhhc16 "zinc finger, DHHC domain containing 16" K18932|1|0.0|656|cge:100757953|palmitoyltransferase [EC:2.3.1.225] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0016740//transferase activity GO:0012501//programmed cell death gi|675710484|ref|XP_009008339.1|/0/PREDICTED: probable palmitoyltransferase ZDHHC16 isoform X1 [Callithrix jacchus] 71904 3832.7 7.14 6.816666667 -0.066857637 Down 0.162886908 Paqr7 progestin and adipoQ receptor family member VII K07297|1|2e-12|78.2|cqu:CpipJ_CPIJ002779|adiponectin receptor - - - - 71591 3514 6.456666667 6.133333333 -0.074118188 Down 0.162886908 Zfp251 zinc finger protein 251 K09228|1|0.0|1314|mmu:71591|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|56090226|ref|NP_001007569.1|/0/zinc finger protein 251 [Mus musculus] 69698 2292 1.806666667 1.646666667 -0.13378181 Down 0.162858701 Slc52a3 "solute carrier protein family 52, member 3" K14620|1|0.0|825|mmu:69698|riboflavin transporter 2 GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0051183//vitamin transporter activity;GO:0051183//vitamin transporter activity;GO:0051183//vitamin transporter activity GO:0044763;GO:0015711//organic anion transport;GO:0050954//sensory perception of mechanical stimulus;GO:0009408//response to heat;GO:0044763;GO:0015711//organic anion transport;GO:0050954//sensory perception of mechanical stimulus;GO:0009408//response to heat;GO:0044763;GO:0015711//organic anion transport;GO:0050954//sensory perception of mechanical stimulus;GO:0009408//response to heat "gi|258679445|ref|NP_081448.2|/0/solute carrier family 52, riboflavin transporter, member 3 isoform 1 precursor [Mus musculus]" 66495 769 202.7533333 208.34 0.039214222 Up 0.162858701 Ndufb3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3 K03959|1|7e-46|186|mmu:66495|NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3 - - - - 329470 3972.28 1.603333333 1.76 0.134501036 Up 0.162858701 Accs 1-aminocyclopropane-1-carboxylate synthase (non-functional) K00815|1|3e-14|84.3|bmor:101742749|tyrosine aminotransferase [EC:2.6.1.5] - GO:0043168//anion binding;GO:0043168//anion binding GO:0008152//metabolic process;GO:0008152//metabolic process gi|595763487|ref|NP_001277711.1|/0/1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform a [Mus musculus] 12345 1780.4 190.8466667 196.3933333 0.041331969 Up 0.162830494 Capzb "capping protein (actin filament) muscle Z-line, beta" "K10365|1|2e-155|551|ssc:100134958|capping protein (actin filament) muscle Z-line, beta" GO:0044291//cell-cell contact zone;GO:0015629//actin cytoskeleton;GO:0030141//secretory granule;GO:0031252//cell leading edge;GO:0031674//I band;GO:0043234//protein complex;GO:0044291//cell-cell contact zone;GO:0015629//actin cytoskeleton;GO:0031252//cell leading edge;GO:0031674//I band;GO:0043234//protein complex;GO:0044291//cell-cell contact zone;GO:0033011//perinuclear theca;GO:0015629//actin cytoskeleton;GO:0030141//secretory granule;GO:0031252//cell leading edge;GO:0031674//I band;GO:0043234//protein complex GO:0003779//actin binding;GO:0015631//tubulin binding;GO:0003779//actin binding;GO:0015631//tubulin binding;GO:0003779//actin binding;GO:0015631//tubulin binding GO:0007599//hemostasis;GO:0000902//cell morphogenesis;GO:0055002//striated muscle cell development;GO:0030031//cell projection assembly;GO:0051693//actin filament capping;GO:0031111//negative regulation of microtubule polymerization or depolymerization;GO:0000902//cell morphogenesis;GO:0055002//striated muscle cell development;GO:0030031//cell projection assembly;GO:0051693//actin filament capping;GO:0031111//negative regulation of microtubule polymerization or depolymerization;GO:0007599//hemostasis;GO:0000902//cell morphogenesis;GO:0055002//striated muscle cell development;GO:0030031//cell projection assembly;GO:0051693//actin filament capping;GO:0031111//negative regulation of microtubule polymerization or depolymerization gi|83649737|ref|NP_001032850.1|/4.8779e-158/F-actin-capping protein subunit beta isoform a [Mus musculus] 59289 3012 1.356666667 1.213333333 -0.161090344 Down 0.16277408 Ackr2 atypical chemokine receptor 2 K04187|1|3e-171|605|mmu:59289|chemokine binding protein 2 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004950//chemokine receptor activity;GO:0019956//chemokine binding;GO:0004950//chemokine receptor activity;GO:0019956//chemokine binding GO:0019221//cytokine-mediated signaling pathway;GO:0002274;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0019221//cytokine-mediated signaling pathway;GO:0002274;GO:0051480//regulation of cytosolic calcium ion concentration gi|31542483|ref|NP_067622.2|/2.74992e-170/atypical chemokine receptor 2 [Mus musculus] 21391 1992 1.37 1.23 -0.155517578 Down 0.16277408 Tbxas1 "thromboxane A synthase 1, platelet" K01832|1|0.0|1020|mmu:21391|thromboxane-A synthase [EC:5.3.99.5] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016491//oxidoreductase activity;GO:0016860//intramolecular oxidoreductase activity GO:0006692;GO:0019229//regulation of vasoconstriction;GO:0030320//cellular monovalent inorganic anion homeostasis gi|79750133|ref|NP_035669.3|/0/thromboxane-A synthase [Mus musculus] 230125 4438 19.5 20.15 0.047305715 Up 0.16277408 Slc25a51 "solute carrier family 25, member 51" "K15110|1|2e-15|88.6|isc:IscW_ISCW017282|solute carrier family 25 (mitochondrial 2-oxodicarboxylate transporter), member 21;K15084|4|1e-13|82.0|xma:102223637|solute carrier family 25 (mitochondrial carrier protein), member 16" GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0051234//establishment of localization gi|74220685|dbj|BAE33610.1|/0/unnamed protein product [Mus musculus] 68053 4735 1.343333333 1.203333333 -0.158781002 Down 0.16277408 Ubxn2b UBX domain protein 2B K14012|1|9e-131|471|oaa:100083013|UBX domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - - gi|26328157|dbj|BAC27819.1|/3.96722e-174/unnamed protein product [Mus musculus] 66859 3563 1.196666667 1.333333333 0.156016156 Up 0.16277408 Slc16a9 "solute carrier family 16 (monocarboxylic acid transporters), member 9" "K08186|1|0.0|1010|mmu:66859|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 9" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0051234//establishment of localization;GO:0044763;GO:0006082//organic acid metabolic process gi|27229004|ref|NP_080083.2|/0/monocarboxylate transporter 9 [Mus musculus] 102614 1361 1.283333333 1.146666667 -0.162449881 Down 0.16277408 Rpp25 ribonuclease P/MRP 25 subunit K14525|1|4e-85|317|mmu:102614|ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5] GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen GO:0004549//tRNA-specific ribonuclease activity;GO:0003676//nucleic acid binding GO:0006399//tRNA metabolic process gi|19527204|ref|NP_598743.1|/3.23123e-84/ribonuclease P protein subunit p25 [Mus musculus] 67876 1748 19.73333333 20.38 0.046519376 Up 0.16277408 Coq10b coenzyme Q10B K18588|1|1e-101|372|mmu:67876|coenzyme Q-binding protein COQ10 - - - - 212111 2841.98 200.3666667 205.6533333 0.037571937 Up 0.162755275 Inpp5a inositol polyphosphate-5-phosphatase A "K01106|1|0.0|786|rno:365382|inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56]" - GO:0019904//protein domain specific binding;GO:0046030//inositol trisphosphate phosphatase activity;GO:0019904//protein domain specific binding;GO:0052743 GO:0046488//phosphatidylinositol metabolic process;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0046488//phosphatidylinositol metabolic process;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0044763 "gi|157821515|ref|NP_001102393.1|/0/type I inositol 1,4,5-trisphosphate 5-phosphatase [Rattus norvegicus]" 12908 4393 210.2266667 215.4966667 0.035719871 Up 0.162745872 Crat carnitine acetyltransferase K00624|1|0.0|1263|mmu:12908|carnitine O-acetyltransferase [EC:2.3.1.7] GO:0019866//organelle inner membrane;GO:0042579//microbody GO:0005515//protein binding;GO:0016406//carnitine O-acyltransferase activity GO:0051234//establishment of localization;GO:0009437//carnitine metabolic process;GO:0044238//primary metabolic process gi|85662408|ref|NP_031786.2|/0/carnitine O-acetyltransferase [Mus musculus] 69004 741 1.106666667 0.976666667 -0.180282577 Down 0.162727068 6330418K02Rik RIKEN cDNA 6330418K02 gene K09677|1|1e-37|158|mmu:330217|galactose-3-O-sulfotransferase 4 [EC:2.8.2.-] - - - - 66634 3481 1.106666667 0.976666667 -0.180282577 Down 0.162727068 Mcm8 minichromosome maintenance 8 homologous recombination repair factor K10737|1|0.0|1470|mmu:66634|DNA helicase MCM8 [EC:3.6.4.12] GO:0031981//nuclear lumen;GO:0042555//MCM complex;GO:0031981//nuclear lumen;GO:0042555//MCM complex GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0003676//nucleic acid binding GO:0007276//gamete generation;GO:0044772//mitotic cell cycle phase transition;GO:0006261//DNA-dependent DNA replication;GO:0000725//recombinational repair;GO:0051320;GO:0007276//gamete generation;GO:0044772//mitotic cell cycle phase transition;GO:0006261//DNA-dependent DNA replication;GO:0000725//recombinational repair;GO:0051320 gi|597517921|ref|NP_001277983.1|/0/DNA helicase MCM8 isoform a [Mus musculus] 237073 5539 1.086666667 0.956666667 -0.183821228 Down 0.162727068 Rbm41 RNA binding motif protein 41 K13157|1|2e-13|80.5|hro:HELRODRAFT_65555|U11/U12 small nuclear ribonucleoprotein 65 kDa protein - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - gi|288541346|ref|NP_001165619.1|/0/RNA-binding protein 41 isoform 3 [Mus musculus] 13714 3671 1.056666667 0.93 -0.184217718 Down 0.162727068 Elk4 "ELK4, member of ETS oncogene family" K04376|1|0.0|690|mmu:13714|ETS domain-containing protein Elk-4 GO:0031981//nuclear lumen GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0016575//histone deacetylation;GO:0006366//transcription from RNA polymerase II promoter gi|153792362|ref|NP_031949.2|/0/ETS domain-containing protein Elk-4 [Mus musculus] 70369 2170.81 9.106666667 9.513333333 0.063027851 Up 0.162680056 Bag5 BCL2-associated athanogene 5 K09559|1|0.0|854|mmu:70369|BCL2-associated athanogene 5 GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0044389//ubiquitin-like protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding GO:0042026//protein refolding;GO:0008219//cell death;GO:0044087;GO:0031397//negative regulation of protein ubiquitination;GO:0042026//protein refolding;GO:0008219//cell death;GO:0044087;GO:0031397//negative regulation of protein ubiquitination;GO:0042026//protein refolding;GO:0008219//cell death;GO:0044087;GO:0031397//negative regulation of protein ubiquitination;GO:0042026//protein refolding;GO:0008219//cell death;GO:0044087;GO:0031397//negative regulation of protein ubiquitination gi|58037205|ref|NP_081680.1|/0/BAG family molecular chaperone regulator 5 [Mus musculus] 114716 2872 9.91 9.503333333 -0.060451424 Down 0.162680056 Spred2 "sprouty-related, EVH1 domain containing 2" "K04703|1|0.0|880|mmu:114716|sprouty-related, EVH1 domain-containing protein" GO:0030133//transport vesicle;GO:0016020//membrane GO:0005126//cytokine receptor binding;GO:0004860//protein kinase inhibitor activity;GO:0019900//kinase binding "GO:0043407//negative regulation of MAP kinase activity;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0032502//developmental process" "gi|15743556|ref|NP_277058.1|/0/sprouty-related, EVH1 domain-containing protein 2 [Mus musculus]" 16453 3757.77 9.476666667 9.883333333 0.060618006 Up 0.162680056 Jak3 Janus kinase 3 K11218|1|0.0|2048|mmu:16453|Janus kinase 3 [EC:2.7.10.2] - - - - 71919 2260 9.71 9.296666667 -0.062757767 Down 0.162680056 Rpap3 RNA polymerase II associated protein 3 K19870|1|3e-26|122|aqu:100633970|sperm-associated antigen 1 - - - gi|13386276|ref|NP_082279.1|/0/RNA polymerase II-associated protein 3 [Mus musculus] 229517 3557 8.896666667 9.303333333 0.064482819 Up 0.162680056 Slc25a44 "solute carrier family 25, member 44" "K15121|1|4e-178|628|rno:365841|solute carrier family 25, member 44" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763 "gi|148683335|gb|EDL15282.1|/0/RIKEN cDNA B430110G05, isoform CRA_b, partial [Mus musculus]" 19876 7568 0.166666667 0.096666667 -0.785875195 Down 0.162595434 Robo1 roundabout guidance receptor 1 "K06753|1|0.0|2936|mmu:19876|roundabout, axon guidance receptor 1" GO:0044297//cell body;GO:0032589//neuron projection membrane;GO:0044424;GO:0031224//intrinsic component of membrane GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0004888//transmembrane signaling receptor activity GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0033598//mammary gland epithelial cell proliferation;GO:0060560//developmental growth involved in morphogenesis;GO:0021827;GO:0016198//axon choice point recognition;GO:0016337//single organismal cell-cell adhesion;GO:0006915//apoptotic process;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0050919//negative chemotaxis gi|122114644|ref|NP_062286.2|/0/roundabout homolog 1 precursor [Mus musculus] 80797 3654 0.1 0.173333333 0.793549123 Up 0.162595434 Clca3a2 chloride channel accessory 3A2 K05030|1|0.0|926|pss:102456534|calcium-activated chloride channel regulator 4;K05027|2|0.0|901|ptg:102964316|calcium-activated chloride channel regulator 1 GO:0016021//integral component of membrane GO:0005216//ion channel activity GO:0015698//inorganic anion transport;GO:0012501//programmed cell death gi|13447394|ref|NP_085104.1|/0/chloride channel calcium activated 3A2 precursor [Mus musculus] 93747 1491 199.9633333 194.9933333 -0.036310681 Down 0.162595434 Echs1 "enoyl Coenzyme A hydratase, short chain, 1, mitochondrial" K07511|1|6e-151|536|mmu:93747|enoyl-CoA hydratase [EC:4.2.1.17] GO:0044429 GO:0016836//hydro-lyase activity GO:0009062//fatty acid catabolic process "gi|29789289|ref|NP_444349.1|/5.01587e-150/enoyl-CoA hydratase, mitochondrial precursor [Mus musculus]" 66236 844.8 2.91 3.11 0.095895427 Up 0.16253902 1500011B03Rik RIKEN cDNA 1500011B03 gene K04676|1|1e-06|55.1|cge:100762264|mothers against decapentaplegic homolog 1 - - - - 75444 880 0.283333333 0.203333333 -0.478653599 Down 0.16253902 1700011I03Rik RIKEN cDNA 1700011I03 gene - - - - "gi|148677910|gb|EDL09857.1|/7.80199e-87/mCG21819, isoform CRA_b, partial [Mus musculus]" 224088 7310 2.856666667 3.053333333 0.096052394 Up 0.16253902 Atp13a3 ATPase type 13A3 K14951|1|0.0|2343|mmu:224088|cation-transporting ATPase 13A3/4/5 [EC:3.6.3.-] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0008324//cation transmembrane transporter activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0043169//cation binding;GO:0008324//cation transmembrane transporter activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0006811//ion transport;GO:0006811//ion transport gi|189339252|ref|NP_001121566.1|/0/probable cation-transporting ATPase 13A3 isoform 2 [Mus musculus] 69071 1333 2.756666667 2.96 0.102672347 Up 0.16253902 Tmem97 transmembrane protein 97 - GO:0000323//lytic vacuole;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0005783//endoplasmic reticulum GO:0005488//binding GO:0055092//sterol homeostasis;GO:0016049//cell growth gi|19526880|ref|NP_598467.1|/1.41132e-76/transmembrane protein 97 [Mus musculus] 14939 1418 0.276666667 0.2 -0.468148836 Down 0.16253902 Gzmb granzyme B K01353|1|4e-135|483|mmu:14939|granzyme B [EC:3.4.21.79] GO:0005768//endosome GO:0005488//binding;GO:0004175//endopeptidase activity GO:0012502//induction of programmed cell death;GO:0097190//apoptotic signaling pathway "gi|7305123|ref|NP_038570.1|/3.5938e-134/granzyme B(G,H) precursor [Mus musculus]" 433804 2827 0.276666667 0.2 -0.468148836 Down 0.16253902 Gm13154 zinc finger protein 985 K09228|1|0.0|1134|mmu:433804|KRAB domain-containing zinc finger protein - - - gi|169646737|ref|NP_001014419.2|/0/uncharacterized protein LOC433804 [Mus musculus] 67338 3425 2.666666667 2.863333333 0.102658131 Up 0.16253902 Rffl ring finger and FYVE like domain containing protein K18592|1|7e-30|135|sko:100372526|gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14];K10641|3|1e-09|68.6|tad:TRIADDRAFT_53391|E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27];K16060|4|1e-08|65.1|spu:581540|baculoviral IAP repeat-containing protein 2/3;K10637|5|2e-08|64.7|tca:664294|E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0032446//protein modification by small protein conjugation;GO:0012501//programmed cell death;GO:0015031//protein transport;GO:0032446//protein modification by small protein conjugation;GO:0012501//programmed cell death;GO:0015031//protein transport;GO:0032446//protein modification by small protein conjugation;GO:0012501//programmed cell death;GO:0015031//protein transport;GO:0032446//protein modification by small protein conjugation;GO:0012501//programmed cell death;GO:0015031//protein transport;GO:0032446//protein modification by small protein conjugation;GO:0012501//programmed cell death;GO:0015031//protein transport "gi|148683726|gb|EDL15673.1|/0/ring finger and FYVE like domain containing protein, isoform CRA_c, partial [Mus musculus]" 24058 1990 2.85 3.046666667 0.096269745 Up 0.16253902 Sigirr single immunoglobulin and toll-interleukin 1 receptor (TIR) domain K05169|1|0.0|800|mmu:24058|single Ig IL-1R-related molecule GO:0031224//intrinsic component of membrane GO:0038023//signaling receptor activity GO:0002526//acute inflammatory response;GO:0044092//negative regulation of molecular function;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0042033//chemokine biosynthetic process gi|110625701|ref|NP_075546.2|/0/single Ig IL-1-related receptor [Mus musculus] 56190 1787 178.94 183.8 0.038660845 Up 0.162529618 Rbm38 RNA binding motif protein 38 K14411|1|3e-10|69.3|hro:HELRODRAFT_73357|RNA-binding protein Musashi;K13186|3|2e-09|67.0|gfr:102032918|RNA-binding protein 3;K12741|5|3e-09|66.2|cin:100184318|heterogeneous nuclear ribonucleoprotein A1/A3 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0003729//mRNA binding "GO:0008283//cell proliferation;GO:0014902//myotube differentiation;GO:0048255//mRNA stabilization;GO:0008380//RNA splicing;GO:0022402//cell cycle process;GO:0030330//DNA damage response, signal transduction by p53 class mediator" "gi|148674675|gb|EDL06622.1|/7.59629e-119/RNA binding motif protein 38, isoform CRA_c, partial [Mus musculus]" 70536 2059 1.6 1.453333333 -0.138706271 Down 0.162529618 Qpct glutaminyl-peptide cyclotransferase (glutaminyl cyclase) K00683|1|0.0|671|mmu:70536|glutaminyl-peptide cyclotransferase [EC:2.3.2.5] - - - - 51902 5594 1.476666667 1.623333333 0.136615074 Up 0.162529618 Rnf24 ring finger protein 24 K15699|1|3e-42|177|gja:107115368|RING finger protein 122 GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - gi|625190305|ref|XP_003499068.2|/3.86015e-83/PREDICTED: RING finger protein 24 [Cricetulus griseus] 209478 4209 1.503333333 1.656666667 0.140118418 Up 0.162529618 Tbc1d12 "TBC1D12: TBC1 domain family, member 12" K20167|1|0.0|664|cmy:102933479|TBC1 domain family member 14 GO:0044464 - - gi|119943133|ref|NP_666064.3|/0/TBC1 domain family member 12 [Mus musculus] 13990 4867.02 1.426666667 1.576666667 0.144229387 Up 0.162529618 Smarcad1 "SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1" K14439|1|0.0|1756|mmu:13990|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 [EC:3.6.4.12] GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0005657//replication fork;GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0005657//replication fork GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0003676//nucleic acid binding "GO:0006310//DNA recombination;GO:0033554//cellular response to stress;GO:0016575//histone deacetylation;GO:0007059//chromosome segregation;GO:0000738//DNA catabolic process, exonucleolytic;GO:0006338//chromatin remodeling;GO:0006310//DNA recombination;GO:0033554//cellular response to stress;GO:0016575//histone deacetylation;GO:0007059//chromosome segregation;GO:0000738//DNA catabolic process, exonucleolytic;GO:0006338//chromatin remodeling" gi|50866|emb|CAA49560.1|/0/enhancer-trap-locus-1 [Mus musculus] 81000 9342 1.603333333 1.456666667 -0.138403614 Down 0.162529618 Rad54l2 RAD54 like 2 (S. cerevisiae) K10876|1|0.0|2591|mmu:81000|RAD54-like protein 2 [EC:3.6.4.12] GO:0043231//intracellular membrane-bounded organelle "GO:0000989//transcription factor activity, transcription factor binding;GO:0003676//nucleic acid binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0019900//kinase binding" - gi|126090612|ref|NP_109655.2|/0/helicase ARIP4 [Mus musculus] 231051 16820 1.676666667 1.523333333 -0.138364235 Down 0.162529618 Kmt2c lysine (K)-specific methyltransferase 2C K09188|1|0.0|8511|mmu:231051|histone-lysine N-methyltransferase MLL3 [EC:2.1.1.43] - - - gi|124487063|ref|NP_001074852.1|/0/histone-lysine N-methyltransferase 2C [Mus musculus] 69681 1427 0.04 0.096666667 1.273018494 Up 0.162510813 Cdk3-ps "cyclin-dependent kinase 3, pseudogene" K02088|1|6e-151|536|cge:100759733|cyclin-dependent kinase 3 [EC:2.7.11.22] - - - - 320253 1754 2.12 1.946666667 -0.123058396 Down 0.162510813 3-Mar membrane-associated ring finger (C3HC4) 3 K10658|1|7e-128|460|mmu:320253|E3 ubiquitin-protein ligase MARCH3 [EC:2.3.2.27] GO:0005769//early endosome;GO:0000323//lytic vacuole;GO:0012506//vesicle membrane;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0016192//vesicle-mediated transport;GO:0032446//protein modification by small protein conjugation gi|28893059|ref|NP_796089.1|/5.66001e-127/E3 ubiquitin-protein ligase MARCH3 [Mus musculus] 12561 6405 2.196666667 2.026666667 -0.116207142 Down 0.162510813 Cdh4 cadherin 4 "K06797|1|0.0|1649|mmu:12561|cadherin 4, type 1, R-cadherin" - - - - 16842 2305 0.043333333 0.106666667 1.299560282 Up 0.162510813 Lef1 lymphoid enhancer binding factor 1 K04492|1|0.0|727|ngi:103742515|lymphoid enhancer-binding factor 1 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle "GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0003707//steroid hormone receptor activity;GO:0019904//protein domain specific binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0003707//steroid hormone receptor activity;GO:0019904//protein domain specific binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding" GO:0021766//hippocampus development;GO:0070670//response to interleukin-4;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0048732//gland development;GO:0007162//negative regulation of cell adhesion;GO:0042113//B cell activation;GO:0009952//anterior/posterior pattern specification;GO:0007423//sensory organ development;GO:0016337//single organismal cell-cell adhesion;GO:0014706//striated muscle tissue development;GO:0001707//mesoderm formation;GO:0016049//cell growth;GO:0051100//negative regulation of binding;GO:0001837//epithelial to mesenchymal transition;GO:0016477//cell migration;GO:0042476//odontogenesis;GO:0012502//induction of programmed cell death;GO:0006935//chemotaxis;GO:0021872//forebrain generation of neurons;GO:0007606//sensory perception of chemical stimulus;GO:0043921;GO:0042981//regulation of apoptotic process;GO:0030178//negative regulation of Wnt signaling pathway;GO:0071898;GO:0016573//histone acetylation;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0010564//regulation of cell cycle process;GO:0035108//limb morphogenesis;GO:0001525//angiogenesis;GO:0002681;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0042088//T-helper 1 type immune response;GO:0001818//negative regulation of cytokine production;GO:0021766//hippocampus development;GO:0070670//response to interleukin-4;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0048732//gland development;GO:0007162//negative regulation of cell adhesion;GO:0042113//B cell activation;GO:0009952//anterior/posterior pattern specification;GO:0007423//sensory organ development;GO:0016337//single organismal cell-cell adhesion;GO:0014706//striated muscle tissue development;GO:0001707//mesoderm formation;GO:0016049//cell growth;GO:0051100//negative regulation of binding;GO:0001837//epithelial to mesenchymal transition;GO:0016477//cell migration;GO:0042476//odontogenesis;GO:0012502//induction of programmed cell death;GO:0006935//chemotaxis;GO:0021872//forebrain generation of neurons;GO:0007606//sensory perception of chemical stimulus;GO:0043921;GO:0042981//regulation of apoptotic process;GO:0030178//negative regulation of Wnt signaling pathway;GO:0071898;GO:0016573//histone acetylation;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0010564//regulation of cell cycle process;GO:0035108//limb morphogenesis;GO:0001525//angiogenesis;GO:0002681;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0042088//T-helper 1 type immune response;GO:0001818//negative regulation of cytokine production gi|568921939|ref|XP_006501133.1|/0/PREDICTED: lymphoid enhancer-binding factor 1 isoform X3 [Mus musculus] 15436 2560 0.043333333 0.106666667 1.299560282 Up 0.162510813 Hoxd4 homeobox D4 K09304|1|4e-112|408|mmu:15436|homeobox protein HoxA/B/C/D4 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0003002//regionalization;GO:0048562//embryonic organ morphogenesis;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated" gi|1791005|gb|AAB41222.1|/3.12098e-111/homeodomain-containing transcription factor [Mus musculus] 71816 3785 0.043333333 0.103333333 1.253756592 Up 0.162510813 Rnf180 ring finger protein 180 K15708|1|0.0|1090|mmu:71816|E3 ubiquitin-protein ligase RNF180 [EC:2.3.2.27] GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane GO:0046914//transition metal ion binding;GO:0044390//ubiquitin-like protein conjugating enzyme binding;GO:0019787//ubiquitin-like protein transferase activity GO:0032446//protein modification by small protein conjugation;GO:0031331 gi|110625861|ref|NP_082210.1|/0/E3 ubiquitin-protein ligase RNF180 [Mus musculus] 77945 4706.67 1.956666667 2.123333333 0.117932869 Up 0.162510813 Rpgrip1 retinitis pigmentosa GTPase regulator interacting protein 1 K16512|1|0.0|1687|mmu:77945|X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0001754//eye photoreceptor cell differentiation;GO:0050953//sensory perception of light stimulus;GO:0043010//camera-type eye development;GO:0001754//eye photoreceptor cell differentiation;GO:0050953//sensory perception of light stimulus;GO:0043010//camera-type eye development gi|270341390|ref|NP_001161987.1|/0/X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 isoform 2 [Mus musculus] 100504268 1394 0.096666667 0.04 -1.273018494 Down 0.162510813 2310005A03Rik RIKEN cDNA 2310005A03 gene - - - - "gi|148674163|gb|EDL06110.1|/1.12311e-31/mCG1027988, partial [Mus musculus]" 16768 2020 0.413333333 0.326666667 -0.339486466 Down 0.162473203 Lag3 lymphocyte-activation gene 3 K06565|1|0.0|924|mmu:16768|lymphocyte-activation gene 3 protein GO:0031224//intrinsic component of membrane;GO:0009986//cell surface GO:0038023//signaling receptor activity;GO:0042287//MHC protein binding GO:0042036//negative regulation of cytokine biosynthetic process;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0007165//signal transduction;GO:0042110//T cell activation gi|6678654|ref|NP_032505.1|/0/lymphocyte activation gene 3 protein precursor [Mus musculus] 622408 2354 0.336666667 0.426666667 0.341788517 Up 0.162473203 Mcidas multiciliate differentiation and DNA synthesis associated cell cycle protein K10749|1|0.0|657|mmu:622408|geminin - GO:0005515//protein binding "GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0006351//transcription, DNA-templated;GO:0016043//cellular component organization" gi|85702306|ref|NP_001033003.1|/0/multicilin [Mus musculus] 13542 3383.36 18.32666667 18.96333333 0.049268174 Up 0.162463801 Dvl1 dishevelled segment polarity protein 1 K02353|1|0.0|954|mmu:13542|segment polarity protein dishevelled - - - - 107975 4361 18.74 19.37666667 0.048199455 Up 0.162463801 Pacs1 phosphofurin acidic cluster sorting protein 1 K16537|1|8e-07|59.7|oaa:100077400|pericentriolar material 1 protein GO:0005798//Golgi-associated vesicle GO:0005515//protein binding "GO:0043393//regulation of protein binding;GO:0006612//protein targeting to membrane;GO:0050688//regulation of defense response to virus;GO:0000301//retrograde transport, vesicle recycling within Golgi" gi|54291704|ref|NP_694769.2|/0/phosphofurin acidic cluster sorting protein 1 [Mus musculus] 27404 6178 0.77 0.656666667 -0.229697222 Down 0.162435594 Abca8b "ATP-binding cassette, sub-family A (ABC1), member 8b" "K05650|1|0.0|3032|mmu:27404|ATP-binding cassette, subfamily A (ABC1), member 8" GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0015405 GO:0009154//purine ribonucleotide catabolic process;GO:0044763;GO:0051234//establishment of localization "gi|148702428|gb|EDL34375.1|/0/mCG118047, isoform CRA_a, partial [Mus musculus]" 16192 3557 0.63 0.736666667 0.225660135 Up 0.162435594 Il5ra "interleukin 5 receptor, alpha" K05067|1|0.0|830|mmu:16192|interleukin 5 receptor alpha GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0006954//inflammatory response;GO:0010033//response to organic substance;GO:0001817//regulation of cytokine production gi|6680431|ref|NP_032396.1|/0/interleukin-5 receptor subunit alpha precursor [Mus musculus] 68846 1351 0.736666667 0.63 -0.225660135 Down 0.162435594 Rnf208 ring finger protein 208 K11983|1|3e-09|65.5|lcm:102348431|E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27] - - - - 237010 3884 0.756666667 0.643333333 -0.23409145 Down 0.162435594 Klhl4 kelch-like 4 K10442|1|0.0|1434|mmu:237010|kelch-like protein 1/4/5 - - - "gi|148701478|gb|EDL33425.1|/0/kelch-like 4 (Drosophila), isoform CRA_b, partial [Mus musculus]" 13001 970.71 147.9466667 152.5233333 0.043952774 Up 0.162416789 Csnk2b "casein kinase 2, beta polypeptide" K03115|1|2e-109|224|tru:101074217|casein kinase II subunit beta GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019207//kinase regulator activity;GO:0005515//protein binding;GO:0043169//cation binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019207//kinase regulator activity;GO:0005515//protein binding;GO:0043169//cation binding" GO:0001934//positive regulation of protein phosphorylation;GO:0003159;GO:0019221//cytokine-mediated signaling pathway;GO:0010596//negative regulation of endothelial cell migration;GO:0032924//activin receptor signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0003159;GO:0019221//cytokine-mediated signaling pathway;GO:0010596//negative regulation of endothelial cell migration;GO:0032924//activin receptor signaling pathway gi|759177751|ref|XP_011378212.1|/9.73073e-119/PREDICTED: LOW QUALITY PROTEIN: casein kinase II subunit beta [Pteropus vampyrus] 76408 5002 0.486666667 0.586666667 0.26960706 Up 0.162388582 Abcc3 "ATP-binding cassette, sub-family C (CFTR/MRP), member 3" "K05667|1|0.0|3005|mmu:76408|ATP-binding cassette, subfamily C (CFTR/MRP), member 3" GO:0016021//integral component of membrane;GO:0044459 "GO:0032550;GO:0042626//ATPase activity, coupled to transmembrane movement of substances" GO:0044763;GO:0015893//drug transport;GO:0043627//response to estrogen;GO:0015721//bile acid and bile salt transport;GO:0009154//purine ribonucleotide catabolic process;GO:0002237//response to molecule of bacterial origin gi|90403595|ref|NP_083876.3|/0/canalicular multispecific organic anion transporter 2 [Mus musculus] 19084 3439.17 145.2233333 149.5166667 0.042033038 Up 0.162256948 Prkar1a "protein kinase, cAMP dependent regulatory, type I, alpha" K04739|1|0.0|724|mmu:19084|cAMP-dependent protein kinase regulator - - - - 12649 3397 0.103333333 0.176666667 0.773724144 Up 0.162238144 Chek1 checkpoint kinase 1 K02216|1|0.0|946|mmu:12649|serine/threonine-protein kinase Chk1 [EC:2.7.11.1] GO:0005815//microtubule organizing center;GO:0044427;GO:0000228//nuclear chromosome GO:0032550;GO:0035184//histone threonine kinase activity GO:0000018//regulation of DNA recombination;GO:0010467//gene expression;GO:0044772//mitotic cell cycle phase transition;GO:0009612//response to mechanical stimulus;GO:0008283//cell proliferation;GO:0007088//regulation of mitotic nuclear division;GO:0000077//DNA damage checkpoint;GO:0006338//chromatin remodeling;GO:0034644//cellular response to UV;GO:0031000//response to caffeine;GO:0035405;GO:0035065//regulation of histone acetylation gi|31542385|ref|NP_031717.2|/0/serine/threonine-protein kinase Chk1 [Mus musculus] 74685 2135 0.22 0.303333333 0.463400521 Up 0.162238144 Lrrc74b leucine rich repeat containing 74B "K07374|1|3e-123|445|hgl:101701752|tubulin alpha;K12800|2|3e-19|99.8|cmk:103172555|NACHT, LRR and PYD domains-containing protein 3;K16634|4|5e-17|92.4|pon:100459061|ribonuclease inhibitor" - - - gi|224177538|ref|NP_001138907.1|/6.24302e-179/leucine-rich repeat-containing protein 74B isoform 2 [Mus musculus] 80794 1677 0.103333333 0.176666667 0.773724144 Up 0.162238144 Cblc Casitas B-lineage lymphoma c K04707|1|0.0|834|mmu:80794|E3 ubiquitin-protein ligase CBL [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0060089;GO:0019904//protein domain specific binding;GO:0070851//growth factor receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0045309//protein phosphorylated amino acid binding GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0016567//protein ubiquitination;GO:0043405//regulation of MAP kinase activity;GO:0019941//modification-dependent protein catabolic process gi|240255497|ref|NP_001155316.1|/0/E3 ubiquitin-protein ligase CBL-C isoform 2 [Mus musculus] 68662 540 0.103333333 0.176666667 0.773724144 Up 0.162238144 Scgb3a1 "secretoglobin, family 3A, member 1" - GO:0005576//extracellular region;GO:0005576//extracellular region - - gi|25014112|ref|NP_733923.1|/5.59279e-28/secretoglobin family 3A member 1 isoform b [Mus musculus] 16795 4683.37 18.56 17.92666667 -0.050089456 Down 0.162209936 Large like-glycosyltransferase K09668|1|0.0|1498|mmu:16795|glycosyltransferase-like protein LARGE - - - - 57320 920 142.5633333 146.67 0.040970837 Up 0.162125315 Park7 "Parkinson disease (autosomal recessive, early onset) 7" K05687|1|2e-101|371|mmu:57320|protein DJ-1 GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0016787//hydrolase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0042802//identical protein binding;GO:0016209//antioxidant activity;GO:0003723//RNA binding" "GO:0007626//locomotory behavior;GO:0032411//positive regulation of transporter activity;GO:0043066//negative regulation of apoptotic process;GO:0031647//regulation of protein stability;GO:0034614//cellular response to reactive oxygen species;GO:0009566//fertilization;GO:0043393//regulation of protein binding;GO:0001963//synaptic transmission, dopaminergic;GO:0030521//androgen receptor signaling pathway;GO:0006996//organelle organization;GO:0044710;GO:0006954//inflammatory response;GO:0072593//reactive oxygen species metabolic process;GO:0042391//regulation of membrane potential;GO:0097191//extrinsic apoptotic signaling pathway;GO:0044248;GO:0019538//protein metabolic process" gi|55741460|ref|NP_065594.2|/1.33352e-100/protein DJ-1 [Mus musculus] 67044 613 151.8566667 155.9533333 0.038404143 Up 0.162125315 Higd2a "HIG1 domain family, member 2A" K01489|1|1e-17|74.7|fca:101092777|cytidine deaminase [EC:3.5.4.5] GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0007005//mitochondrion organization;GO:0006915//apoptotic process;GO:0006091//generation of precursor metabolites and energy gi|13385426|ref|NP_080209.1|/1.76012e-54/HIG1 domain family member 2A [Mus musculus] 228765 1412 0.846666667 0.97 0.196190656 Up 0.16210651 Sdcbp2 syndecan binding protein (syntenin) 2 K17254|1|3e-88|328|xma:102222452|syntenin-1 GO:0044424 GO:0046983//protein dimerization activity;GO:0042802//identical protein binding - "gi|148673971|gb|EDL05918.1|/2.6305e-153/syndecan binding protein (syntenin) 2, partial [Mus musculus]" 280668 3114 0.8 0.916666667 0.196397213 Up 0.16210651 Adam1a a disintegrin and metallopeptidase domain 1a K08607|1|0.0|1533|mmu:280668|disintegrin and metalloproteinase domain-containing protein 1 [EC:3.4.24.-] GO:0031224//intrinsic component of membrane "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0035036//sperm-egg recognition;GO:0048232//male gamete generation gi|31559889|ref|NP_742124.2|/0/disintegrin and metalloproteinase domain-containing protein 1a precursor [Mus musculus] 238693 2365 0.95 0.826666667 -0.200621799 Down 0.16210651 Zfp58 zinc finger protein 58 K09228|1|0.0|1071|mmu:238693|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|56119156|ref|NP_001007576.1|/0/zinc finger protein 58 [Mus musculus] 22756 2621 0.616666667 0.516666667 -0.255257055 Down 0.162087705 Zfp94 zinc finger protein 94 K09228|1|0.0|1051|mmu:22756|KRAB domain-containing zinc finger protein GO:0005622//intracellular - "GO:0006351//transcription, DNA-templated" gi|313482845|ref|NP_001186250.1|/0/zinc finger protein 45 isoform 1 [Mus musculus] 100040608 1691 0.496666667 0.593333333 0.256564911 Up 0.162087705 Fancf "Fanconi anemia, complementation group F" K10893|1|3e-166|587|mmu:100040608|fanconi anemia group F protein GO:0043234//protein complex - - gi|169259776|ref|NP_001108559.1|/2.9371e-165/Fanconi anemia group F protein [Mus musculus] 100504692 2475 0.043333333 0.1 1.206450877 Up 0.162068901 Gm20356 "predicted gene, 20356" - - - - "gi|954520284|gb|KRZ46818.1|/4.45938e-06/hypothetical protein T02_14008, partial [Trichinella nativa]" 278672 2028 0.096666667 0.163333333 0.756728849 Up 0.162068901 Duxbl1 double homeobox B-like 1 K09337|1|2e-13|80.5|myd:102758751|cone-rod homeobox protein;K18490|2|2e-12|77.0|obi:106873941|homeobox protein OTX2;K09326|5|2e-12|76.6|dre:353179|homeobox protein OTX1 - - - gi|34419645|ref|NP_899245.1|/0/double homeobox B-like 1 [Mus musculus] 237175 4642 0.18 0.106666667 -0.754887502 Down 0.162068901 Adgrg2 adhesion G protein-coupled receptor G2 K08451|1|0.0|1669|mmu:237175|G protein-coupled receptor 64 GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway "gi|148708858|gb|EDL40805.1|/0/G protein-coupled receptor 64, partial [Mus musculus]" 320452 2361 0.106666667 0.046666667 -1.192645078 Down 0.162068901 P4ha3 "procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III" K00472|1|0.0|1026|mmu:320452|prolyl 4-hydroxylase [EC:1.14.11.2] GO:0043234//protein complex;GO:0044432 "GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0019798//procollagen-proline dioxygenase activity;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0044710 gi|755522787|ref|XP_011240133.1|/0/PREDICTED: prolyl 4-hydroxylase subunit alpha-3 isoform X2 [Mus musculus] 102920 3624 0.163333333 0.096666667 -0.756728849 Down 0.162068901 Cenpi centromere protein I K11501|1|0.0|1468|mmu:102920|centromere protein I "GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region;GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region" - GO:0001541//ovarian follicle development;GO:0001541//ovarian follicle development gi|22122337|ref|NP_666036.1|/0/centromere protein I [Mus musculus] 66942 2249 10.06666667 9.666666667 -0.058495649 Down 0.162040694 Ddx18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 K13179|1|0.0|1162|mmu:66942|ATP-dependent RNA helicase DDX18/HAS1 [EC:3.6.4.13] GO:0031981//nuclear lumen "GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550" - gi|31981163|ref|NP_080136.2|/0/ATP-dependent RNA helicase DDX18 [Mus musculus] 140481 6575 17.13333333 16.51333333 -0.053174491 Down 0.161974877 Man2a2 "mannosidase 2, alpha 2" K01231|1|0.0|2275|mmu:140481|alpha-mannosidase II [EC:3.2.1.114] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0015924//mannosyl-oligosaccharide mannosidase activity GO:0019318//hexose metabolic process gi|326937500|ref|NP_766491.2|/0/alpha-mannosidase 2x [Mus musculus] 170930 998 125.46 129.3333333 0.043866684 Up 0.161965474 Sumo2 small ubiquitin-like modifier 2 K12160|1|3e-48|182|hgl:101706735|small ubiquitin-related modifier GO:0016604//nuclear body GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity GO:0006366//transcription from RNA polymerase II promoter;GO:0008104//protein localization;GO:0031331;GO:0032446//protein modification by small protein conjugation gi|829944637|ref|XP_012598516.1|/2.16693e-54/PREDICTED: uncharacterized protein LOC105859346 [Microcebus murinus] 66663 2402 6.446666667 6.756666667 0.067758294 Up 0.161927865 Uba5 ubiquitin-like modifier activating enzyme 5 K12164|1|0.0|679|mmu:66663|ubiquitin-like modifier-activating enzyme 5 GO:0016234//inclusion body;GO:0043231//intracellular membrane-bounded organelle "GO:0008641//small protein activating enzyme activity;GO:0043169//cation binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0032550" GO:0032446//protein modification by small protein conjugation;GO:0044710 gi|227499242|ref|NP_079968.2|/0/ubiquitin-like modifier-activating enzyme 5 [Mus musculus] 215160 4171 6.586666667 6.276666667 -0.069549947 Down 0.161927865 Rhbdd2 rhomboid domain containing 2 K09652|1|0.0|664|mmu:215160|rhomboid domain-containing protein 2 GO:0031224//intrinsic component of membrane GO:0004175//endopeptidase activity - gi|22122463|ref|NP_666114.1|/0/rhomboid domain-containing protein 2 [Mus musculus] 378460 2286 0.3 0.22 -0.447458977 Down 0.161843243 Pram1 PML-RAR alpha-regulated adaptor molecule 1 K19994|1|0.0|1246|mmu:378460|PML-RARA-regulated adapter molecule 1 - - - "gi|148678251|gb|EDL10198.1|/0/mCG140116, isoform CRA_b, partial [Mus musculus]" 244059 9071 4.41 4.16 -0.084195127 Down 0.161833841 Chd2 chromodomain helicase DNA binding protein 2 K20091|1|0.0|2921|mmu:244059|chromodomain-helicase-DNA-binding protein 2 [EC:3.6.4.12] GO:0043231//intracellular membrane-bounded organelle GO:0003678//DNA helicase activity;GO:0032550;GO:0003676//nucleic acid binding GO:0006366//transcription from RNA polymerase II promoter gi|189458810|ref|NP_001074814.2|/0/chromodomain-helicase-DNA-binding protein 2 [Mus musculus] 71703 3385 4.453333333 4.203333333 -0.083351732 Down 0.161833841 Armcx3 "armadillo repeat containing, X-linked 3" - GO:0031306//intrinsic component of mitochondrial outer membrane - GO:0008104//protein localization;GO:0006366//transcription from RNA polymerase II promoter gi|261862275|ref|NP_082146.2|/0/armadillo repeat-containing X-linked protein 3 [Mus musculus] 54189 5328.81 4.97 4.716666667 -0.075478205 Down 0.161833841 Rabep1 "rabaptin, RAB GTPase binding effector protein 1" K12480|1|0.0|1465|mmu:54189|Rab GTPase-binding effector protein 1 "GO:0005768//endosome;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005768//endosome;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005768//endosome;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005768//endosome;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0042802//identical protein binding;GO:0008047//enzyme activator activity;GO:0005102//receptor binding;GO:0042802//identical protein binding;GO:0008047//enzyme activator activity;GO:0005102//receptor binding;GO:0042802//identical protein binding;GO:0008047//enzyme activator activity;GO:0005102//receptor binding;GO:0042802//identical protein binding;GO:0008047//enzyme activator activity;GO:0005102//receptor binding GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport;GO:0012501//programmed cell death;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport;GO:0012501//programmed cell death;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport;GO:0012501//programmed cell death;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport;GO:0012501//programmed cell death gi|238231439|ref|NP_062273.2|/0/rab GTPase-binding effector protein 1 isoform 1 [Mus musculus] 225861 1715 4.266666667 4.516666667 0.082149041 Up 0.161833841 Snx32 sorting nexin 32 K17920|1|0.0|753|mmu:225861|sorting nexin-5/6/32 - GO:0005543//phospholipid binding GO:0045184//establishment of protein localization;GO:0044763 gi|755562377|ref|XP_011246919.1|/0/PREDICTED: sorting nexin-32 isoform X1 [Mus musculus] 67870 1844 4.573333333 4.326666667 -0.079990098 Down 0.161833841 Enoph1 enolase-phosphatase 1 K09880|1|7e-121|421|mmu:67870|enolase-phosphatase E1 [EC:3.1.3.77] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046872//metal ion binding;GO:0016791//phosphatase activity;GO:0046872//metal ion binding;GO:0016791//phosphatase activity;GO:0046872//metal ion binding;GO:0016791//phosphatase activity GO:0000097//sulfur amino acid biosynthetic process;GO:0006576//cellular biogenic amine metabolic process;GO:0043102;GO:0000097//sulfur amino acid biosynthetic process;GO:0006576//cellular biogenic amine metabolic process;GO:0043102;GO:0000097//sulfur amino acid biosynthetic process;GO:0006576//cellular biogenic amine metabolic process;GO:0043102 "gi|148688359|gb|EDL20306.1|/1.25264e-148/RIKEN cDNA 2310057D15, isoform CRA_b, partial [Mus musculus]" 75320 6447 4.593333333 4.843333333 0.076458815 Up 0.161833841 Etnk1 ethanolamine kinase 1 K00894|1|0.0|756|mmu:75320|ethanolamine kinase [EC:2.7.1.82] GO:0044424 GO:0016301//kinase activity;GO:0032550 GO:0046337//phosphatidylethanolamine metabolic process gi|26328955|dbj|BAC28216.1|/0/unnamed protein product [Mus musculus] 67460 3082 123.62 127.13 0.040392346 Up 0.161721012 Decr1 "2,4-dienoyl CoA reductase 1, mitochondrial" "K13236|1|0.0|671|mmu:67460|2,4-dienoyl-CoA reductase, mitochondrial [EC:1.3.1.34]" GO:0031981//nuclear lumen "GO:0043168//anion binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor" GO:0051260//protein homooligomerization;GO:0009062//fatty acid catabolic process "gi|13385680|ref|NP_080448.1|/0/2,4-dienoyl-CoA reductase, mitochondrial precursor [Mus musculus]" 71835 3657 3.686666667 3.47 -0.087381317 Down 0.16171161 Lancl2 LanC (bacterial lantibiotic synthetase component C)-like 2 K17509|1|8e-50|202|cqu:CpipJ_CPIJ006058|pyruvate dehydrogenase phosphatase regulatory subunit;K19522|2|7e-35|152|chx:102176212|membrane transport protein XK GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0044444//cytoplasmic part GO:0032550;GO:1901981//phosphatidylinositol phosphate binding "GO:0006351//transcription, DNA-templated;GO:0009738//abscisic acid-activated signaling pathway" gi|19526936|ref|NP_598498.1|/0/lanC-like protein 2 [Mus musculus] 110279 6537 3.713333333 3.49 -0.08948779 Down 0.16171161 Bcr breakpoint cluster region K08878|1|0.0|2168|mmu:110279|breakpoint cluster region protein [EC:2.7.11.1] GO:0016020//membrane;GO:0044444//cytoplasmic part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0032550;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0008289//lipid binding GO:0007010//cytoskeleton organization;GO:0006909//phagocytosis;GO:0007266//Rho protein signal transduction;GO:0007417//central nervous system development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0002695//negative regulation of leukocyte activation;GO:0006468//protein phosphorylation;GO:0042471//ear morphogenesis;GO:0006954//inflammatory response;GO:0002237//response to molecule of bacterial origin;GO:0016477//cell migration;GO:0007049//cell cycle;GO:0050905//neuromuscular process gi|124487229|ref|NP_001074881.1|/0/breakpoint cluster region protein [Mus musculus] 101118 4548 3.416666667 3.636666667 0.090027192 Up 0.16171161 Tmem168 transmembrane protein 168 - "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031224//intrinsic component of membrane" - - gi|27532967|ref|NP_083266.1|/0/transmembrane protein 168 [Mus musculus] 100504714 1746 3.663333333 3.446666667 -0.087955201 Down 0.16171161 Gm16793 "predicted gene, 16793" - - - - gi|148703506|gb|EDL35453.1|/3.75494e-30/mCG1051092 [Mus musculus] 14872 1370 3.853333333 3.63 -0.086137444 Down 0.16171161 Gstt2 "glutathione S-transferase, theta 2" K00799|1|6e-136|486|mmu:14872|glutathione S-transferase [EC:2.5.1.18] GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen "GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups" GO:0006790//sulfur compound metabolic process gi|158081796|ref|NP_034491.2|/5.30366e-135/glutathione S-transferase theta-2 [Mus musculus] 20773 6725 3.356666667 3.573333333 0.090241222 Up 0.16171161 Sptlc2 "serine palmitoyltransferase, long chain base subunit 2" K00654|1|0.0|1091|mmu:20773|serine palmitoyltransferase [EC:2.3.1.50] - - - - 67900 1396 109.4733333 112.9066667 0.044551188 Up 0.161664598 Mtfp1 mitochondrial fission process 1 K17981|1|2e-90|335|mmu:67900|mitochondrial fission process protein 1 GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0007005//mitochondrion organization;GO:0012501//programmed cell death gi|31980939|ref|NP_080719.2|/1.54193e-89/mitochondrial fission process protein 1 [Mus musculus] 53421 3039 16.12 16.73 0.053585702 Up 0.161617586 Sec61a1 Sec61 alpha 1 subunit (S. cerevisiae) K10956|1|0.0|931|mdo:100027900|protein transport protein SEC61 subunit alpha GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0043021//ribonucleoprotein complex binding GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0006605//protein targeting;GO:0034097//response to cytokine gi|7019415|ref|NP_037468.1|/0/protein transport protein Sec61 subunit alpha isoform 1 [Homo sapiens] 20562 5300 0.06 0.013333333 -2.169925001 Down 0.16155177 Slit1 slit homolog 1 (Drosophila) K06838|1|0.0|3000|mmu:20562|slit 1 GO:0044424;GO:0044421 GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0043168//anion binding GO:0007411//axon guidance;GO:0051647//nucleus localization;GO:0030517//negative regulation of axon extension;GO:0007416//synapse assembly;GO:0021831//embryonic olfactory bulb interneuron precursor migration "gi|148709913|gb|EDL41859.1|/0/slit homolog 1 (Drosophila), isoform CRA_b, partial [Mus musculus]" 104382 2329 0.103333333 0.046666667 -1.146841388 Down 0.16155177 Barhl2 BarH-like 2 (Drosophila) K09360|1|5e-179|630|mmu:104382|BarH-like GO:0043231//intracellular membrane-bounded organelle "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0003677//DNA binding" GO:0048638//regulation of developmental growth;GO:0006366//transcription from RNA polymerase II promoter;GO:0006412//translation;GO:0045165//cell fate commitment;GO:0016477//cell migration;GO:0030182//neuron differentiation gi|56699436|ref|NP_001005477.1|/4.51547e-178/barH-like 2 homeobox protein [Mus musculus] 110075 6229 0.11 0.05 -1.137503524 Down 0.16155177 Bmp3 bone morphogenetic protein 3 K05496|1|0.0|960|mmu:110075|bone morphogenetic protein 3/3B - - - - 58208 7341 0.11 0.05 -1.137503524 Down 0.16155177 Bcl11b B cell leukemia/lymphoma 11B K09228|1|6e-17|94.0|rno:501406|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046872//metal ion binding" GO:0007411//axon guidance;GO:0042127//regulation of cell proliferation;GO:0008544//epidermis development;GO:0006366//transcription from RNA polymerase II promoter;GO:0021756//striatum development;GO:0042476//odontogenesis;GO:0045058//T cell selection;GO:0009791//post-embryonic development;GO:0006915//apoptotic process;GO:0002681;GO:0006629//lipid metabolic process;GO:0002064//epithelial cell development;GO:0007411//axon guidance;GO:0042127//regulation of cell proliferation;GO:0008544//epidermis development;GO:0006366//transcription from RNA polymerase II promoter;GO:0021756//striatum development;GO:0042476//odontogenesis;GO:0045058//T cell selection;GO:0009791//post-embryonic development;GO:0006915//apoptotic process;GO:0002681;GO:0006629//lipid metabolic process;GO:0002064//epithelial cell development;GO:0007411//axon guidance;GO:0042127//regulation of cell proliferation;GO:0008544//epidermis development;GO:0006366//transcription from RNA polymerase II promoter;GO:0021756//striatum development;GO:0042476//odontogenesis;GO:0045058//T cell selection;GO:0009791//post-embryonic development;GO:0006915//apoptotic process;GO:0002681;GO:0006629//lipid metabolic process;GO:0002064//epithelial cell development gi|120586999|ref|NP_067374.2|/0/B-cell lymphoma/leukemia 11B isoform b [Mus musculus] 414084 3769 0.36 0.45 0.321928095 Up 0.161467148 Tnip3 TNFAIP3 interacting protein 3 - - GO:0043130//ubiquitin binding GO:0002224//toll-like receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0032496//response to lipopolysaccharide gi|568942362|ref|XP_006506422.1|/8.87564e-105/PREDICTED: TNFAIP3-interacting protein 3 isoform X1 [Mus musculus] 170952 905 0.223333333 0.303333333 0.44170545 Up 0.161448343 Prima1 proline rich membrane anchor 1 - GO:0031224//intrinsic component of membrane GO:0005515//protein binding GO:0051234//establishment of localization;GO:0042133//neurotransmitter metabolic process "gi|148686897|gb|EDL18844.1|/2.14137e-87/mCG18593, isoform CRA_b, partial [Mus musculus]" 66383 887 110.9366667 114.1366667 0.041026053 Up 0.161429539 Iscu iron-sulfur cluster assembly enzyme K04488|1|9e-59|229|xtr:394688|nitrogen fixation protein NifU and related proteins;K19195|3|8e-47|189|tsp:Tsp_08151|AT-rich interactive domain-containing protein 4B - - - - 74525 4225 2.326666667 2.15 -0.113927876 Down 0.161373124 Fam234b "family with sequence similarity 234, member B" K17258|1|2e-57|227|cmk:103188415|integrin alpha FG-GAP repeat containing protein 3 GO:0031224//intrinsic component of membrane - - gi|31560063|ref|NP_083258.2|/0/uncharacterized protein KIAA1467 [Mus musculus] 72254 2441 2.366666667 2.546666667 0.105753614 Up 0.161373124 1700030K09Rik RIKEN cDNA 1700030K09 gene - - - - gi|755526028|ref|XP_011240630.1|/0/PREDICTED: uncharacterized protein C19orf44 homolog isoform X1 [Mus musculus] 11352 10402 2.493333333 2.316666667 -0.106025292 Down 0.161373124 Abl2 "v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)" K08887|1|0.0|1946|rno:304883|abelson tyrosine-protein kinase 2 [EC:2.7.10.2] GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton GO:0046914//transition metal ion binding;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0046914//transition metal ion binding;GO:0032550;GO:0004713//protein tyrosine kinase activity GO:0043085//positive regulation of catalytic activity;GO:0032526//response to retinoic acid;GO:0010975//regulation of neuron projection development;GO:0022610;GO:0006468//protein phosphorylation;GO:0007015//actin filament organization;GO:0043085//positive regulation of catalytic activity;GO:0032526//response to retinoic acid;GO:0010975//regulation of neuron projection development;GO:0022610;GO:0006468//protein phosphorylation;GO:0007015//actin filament organization gi|209870055|ref|NP_001129576.1|/0/Abelson tyrosine-protein kinase 2 isoform a [Mus musculus] 229681 5786.12 2.403333333 2.223333333 -0.112312498 Down 0.161373124 St7l suppression of tumorigenicity 7-like "K03847|1|5e-06|57.4|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0043062//extracellular structure organization;GO:0016049//cell growth;GO:0030154//cell differentiation;GO:0043062//extracellular structure organization;GO:0016049//cell growth;GO:0030154//cell differentiation;GO:0043062//extracellular structure organization;GO:0016049//cell growth;GO:0030154//cell differentiation gi|532054205|ref|XP_005369829.1|/0/PREDICTED: suppressor of tumorigenicity 7 protein-like isoform X2 [Microtus ochrogaster] 100048644 322 2.52 2.34 -0.106915204 Down 0.161373124 Pet117 PET117 homolog K18188|1|3e-29|128|mmu:100048644|protein PET117 - - - "gi|258679439|ref|NP_001158285.1|/3.09166e-28/protein PET117 homolog, mitochondrial precursor [Mus musculus]" 93697 4070 0.673333333 0.786666667 0.224431567 Up 0.16131671 Ice2 interactor of little elongation complex ELL subunit 2 - - - - gi|34594671|ref|NP_663593.2|/0/little elongation complex subunit 2 [Mus musculus] 74552 5025 9.98 10.37333333 0.055767839 Up 0.161260296 Nipal3 NIPA-like domain containing 3 K19364|1|3e-06|58.2|lcm:102366004|magnesium transporter NIPA1 GO:0031224//intrinsic component of membrane - GO:0070838//divalent metal ion transport gi|58037383|ref|NP_083271.1|/0/NIPA-like protein 3 [Mus musculus] 69155 2680 9.953333333 10.34666667 0.055914392 Up 0.161260296 1810030O07Rik RIKEN cDNA 1810030O07 gene K12805|1|1e-06|58.2|bfo:BRAFLDRAFT_91835|NLR family CARD domain-containing protein 4 - - - - 66098 1126 9.426666667 9.813333333 0.057995551 Up 0.161260296 Chchd6 coiled-coil-helix-coiled-coil-helix domain containing 6 "K17564|1|1e-106|388|mmu:66098|coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0033554//cellular response to stress;GO:0007007//inner mitochondrial membrane organization;GO:0033554//cellular response to stress;GO:0007007//inner mitochondrial membrane organization gi|267844804|ref|NP_079627.3|/1.12396e-105/MICOS complex subunit Mic25 isoform 1 [Mus musculus] 24128 3383 8.913333333 9.306666667 0.062299476 Up 0.161260296 Xrn2 5'-3' exoribonuclease 2 K12619|1|0.0|1877|mmu:24128|5'-3' exoribonuclease 2 [EC:3.1.13.-] GO:0031981//nuclear lumen;GO:0016234//inclusion body GO:0008409//5'-3' exonuclease activity;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding "GO:0006396//RNA processing;GO:0044763;GO:0040007//growth;GO:0006308//DNA catabolic process;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated" "gi|148696569|gb|EDL28516.1|/0/5'-3' exoribonuclease 2, isoform CRA_d, partial [Mus musculus]" 74164 4507.69 9.173333333 8.783333333 -0.062677508 Down 0.161260296 Nfx1 "nuclear transcription factor, X-box binding 1" K12236|1|0.0|2255|mmu:74164|transcriptional repressor NF-X1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003824//catalytic activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003824//catalytic activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003824//catalytic activity GO:0010558;GO:0006366//transcription from RNA polymerase II promoter;GO:0010558;GO:0006366//transcription from RNA polymerase II promoter;GO:0010558;GO:0006366//transcription from RNA polymerase II promoter gi|755506897|ref|XP_011248425.1|/0/PREDICTED: transcriptional repressor NF-X1 isoform X1 [Mus musculus] 103967 4844.48 1.186666667 1.056666667 -0.167394401 Down 0.161213284 Dnm3 dynamin 3 K01528|1|0.0|1477|mmu:103967|dynamin GTPase [EC:3.6.5.5] GO:0044327//dendritic spine head;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part;GO:0044327//dendritic spine head;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008289//lipid binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008289//lipid binding GO:0016192//vesicle-mediated transport;GO:0030031//cell projection assembly;GO:0009154//purine ribonucleotide catabolic process;GO:0007399//nervous system development;GO:0016192//vesicle-mediated transport;GO:0030031//cell projection assembly;GO:0009154//purine ribonucleotide catabolic process;GO:0007399//nervous system development gi|27369922|ref|NP_766234.1|/0/dynamin-3 isoform 2 [Mus musculus] 22156 2561 1.223333333 1.09 -0.166489427 Down 0.161213284 Tuft1 tuftelin 1 K16464|1|7e-12|75.5|ola:101166347|centrosomal protein CEP250 GO:0044424 GO:0030021//extracellular matrix structural constituent conferring compression resistance GO:0009887//organ morphogenesis;GO:0009888//tissue development;GO:0001503//ossification;GO:0009888//tissue development gi|6755903|ref|NP_035786.1|/0/tuftelin isoform 1 [Mus musculus] 100662 3809 1.05 1.183333333 0.172467196 Up 0.161213284 D930016D06Rik RIKEN cDNA D930016D06 gene - - - - - 215693 3520 1.07 1.2 0.165423609 Up 0.161213284 Zmat1 "zinc finger, matrin type 1" "K10137|1|9e-06|55.8|lcm:102347863|zinc finger, matrin type 3" GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - gi|111185887|ref|NP_780655.2|/0/zinc finger matrin-type protein 1 [Mus musculus] 18440 2281 1.173333333 1.043333333 -0.169412772 Down 0.161213284 P2rx6 "purinergic receptor P2X, ligand-gated ion channel, 6" K05221|1|0.0|797|mmu:18440|P2X purinoceptor 6 - - - gi|227116253|ref|NP_001153033.1|/0/P2X purinoceptor 6 isoform 2 [Mus musculus] 238690 3488 0.116666667 0.056666667 -1.041820176 Down 0.161175674 Zfp458 zinc finger protein 458 K09228|1|0.0|1632|mmu:238690|KRAB domain-containing zinc finger protein - GO:0005488//binding - gi|47564121|ref|NP_001001152.1|/0/zinc finger protein 728 [Mus musculus] 110895 3822 0.053333333 0.11 1.044394119 Up 0.161175674 Slc9a4 "solute carrier family 9 (sodium/hydrogen exchanger), member 4" "K13961|1|0.0|1434|mmu:110895|solute carrier family 9 (sodium/hydrogen exchanger), member 4" GO:0044459;GO:0031224//intrinsic component of membrane GO:0005451//monovalent cation:proton antiporter activity GO:0044763;GO:0055067;GO:0030001//metal ion transport gi|45238583|ref|NP_796058.1|/0/sodium/hydrogen exchanger 4 precursor [Mus musculus] 75502 898 0.116666667 0.053333333 -1.129283017 Down 0.161175674 Cmtm2b CKLF-like MARVEL transmembrane domain containing 2B - GO:0044421;GO:0031224//intrinsic component of membrane - GO:0042221//response to chemical gi|21729765|ref|NP_082800.1|/2.02578e-98/CKLF-like MARVEL transmembrane domain-containing protein 2B [Mus musculus] 16538 2727 0.113333333 0.056666667 -1 Down 0.161175674 Kcns1 "K+ voltage-gated channel, subfamily S, 1" K04931|1|0.0|864|mmu:16538|potassium voltage-gated channel delayed-rectifier subfamily S member 1 GO:0005887//integral component of plasma membrane GO:0005249//voltage-gated potassium channel activity;GO:0016247//channel regulator activity GO:0051259//protein oligomerization;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|112821679|ref|NP_032461.2|/0/potassium voltage-gated channel subfamily S member 1 [Mus musculus] 77777 1819 0.11 0.053333333 -1.044394119 Down 0.161175674 Ulbp1 UL16 binding protein 1 K07986|1|2e-177|624|mmu:77777|UL16 binding protein - - - - 208665 2713 0.06 0.12 1 Up 0.161175674 Akr1d1 "aldo-keto reductase family 1, member D1" K00251|1|0.0|671|mmu:208665|3-oxo-5-beta-steroid 4-dehydrogenase [EC:1.3.1.3] GO:0044444//cytoplasmic part "GO:0008289//lipid binding;GO:0033765//steroid dehydrogenase activity, acting on the CH-CH group of donors;GO:0035671//enone reductase activity" GO:0006706//steroid catabolic process;GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0044707 gi|21703734|ref|NP_663339.1|/0/3-oxo-5-beta-steroid 4-dehydrogenase [Mus musculus] 11514 4974 0.116666667 0.056666667 -1.041820176 Down 0.161175674 Adcy8 adenylate cyclase 8 K08048|1|0.0|2338|mmu:11514|adenylate cyclase 8 [EC:4.6.1.1] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0032550;GO:0004016//adenylate cyclase activity;GO:0043169//cation binding;GO:0032550;GO:0004016//adenylate cyclase activity GO:0007613//memory;GO:0009165//nucleotide biosynthetic process;GO:0046058//cAMP metabolic process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0007613//memory;GO:0009165//nucleotide biosynthetic process;GO:0046058//cAMP metabolic process;GO:0019935//cyclic-nucleotide-mediated signaling gi|631790815|ref|NP_001278832.1|/0/adenylate cyclase type 8 isoform 2 [Mus musculus] 16981 3544 0.11 0.053333333 -1.044394119 Down 0.161175674 Lrrn3 "leucine rich repeat protein 3, neuronal" K16351|1|6e-34|149|sko:100378039|netrin-G2 ligand;K07523|4|2e-31|141|bfo:BRAFLDRAFT_64092|netrin-G1 ligand - - - - 18976 1008 0.106666667 0.05 -1.093109404 Down 0.161175674 Pomc pro-opiomelanocortin-alpha K05228|1|2e-103|378|mmu:18976|proopiomelanocortin "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0044439;GO:0044421;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0044439;GO:0044421;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0044439;GO:0044421" GO:0031779//melanocortin receptor binding;GO:0031779//melanocortin receptor binding;GO:0031779//melanocortin receptor binding GO:0043473//pigmentation;GO:0031667//response to nutrient levels;GO:0001818//negative regulation of cytokine production;GO:0007165//signal transduction;GO:0007610//behavior;GO:0008015//blood circulation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043473//pigmentation;GO:0031667//response to nutrient levels;GO:0001818//negative regulation of cytokine production;GO:0007165//signal transduction;GO:0007610//behavior;GO:0008015//blood circulation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043473//pigmentation;GO:0031667//response to nutrient levels;GO:0001818//negative regulation of cytokine production;GO:0007165//signal transduction;GO:0007610//behavior;GO:0008015//blood circulation;GO:0006366//transcription from RNA polymerase II promoter "gi|148669437|gb|EDL01384.1|/2.64738e-108/pro-opiomelanocortin-alpha, isoform CRA_c, partial [Mus musculus]" 26970 851 0.12 0.056666667 -1.08246216 Down 0.161175674 Pla2g2e "phospholipase A2, group IIE" K01047|1|3e-71|270|mmu:26970|secretory phospholipase A2 [EC:3.1.1.4] - GO:0046872//metal ion binding;GO:0004620//phospholipase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006629//lipid metabolic process gi|6755092|ref|NP_036174.1|/2.13153e-70/group IIE secretory phospholipase A2 precursor [Mus musculus] 105246056 918 0.12 0.06 -1 Down 0.161175674 LOC105246056 uncharacterized LOC105246056 - - - - - 213311 1965 0.056666667 0.12 1.08246216 Up 0.161175674 Fbxl21 F-box and leucine-rich repeat protein 21 K10287|1|0.0|835|mmu:213311|F-box and leucine-rich repeat protein 21 - - - "gi|148709293|gb|EDL41239.1|/0/mCG122740, isoform CRA_a [Mus musculus]" 12062 1680 0.12 0.056666667 -1.08246216 Down 0.161175674 Bdkrb2 "bradykinin receptor, beta 2" K03916|1|0.0|731|mmu:12062|bradykinin receptor B2 GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0031701//angiotensin receptor binding;GO:0046983//protein dimerization activity;GO:0008528//G-protein coupled peptide receptor activity;GO:0019899//enzyme binding GO:0007166//cell surface receptor signaling pathway;GO:0042221//response to chemical;GO:0015909//long-chain fatty acid transport;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0002437//inflammatory response to antigenic stimulus;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0001933//negative regulation of protein phosphorylation;GO:0006970//response to osmotic stress;GO:0001666//response to hypoxia;GO:0007600//sensory perception;GO:0050880//regulation of blood vessel size;GO:0008217//regulation of blood pressure "gi|148686811|gb|EDL18758.1|/0/bradykinin receptor, beta 2, isoform CRA_a, partial [Mus musculus]" 84544 2203 0.05 0.106666667 1.093109404 Up 0.161175674 Cd96 CD96 antigen K06517|1|0.0|1158|mmu:84544|CD96 antigen GO:0031224//intrinsic component of membrane - - gi|160333634|ref|NP_115854.2|/0/T-cell surface protein tactile precursor [Mus musculus] 69655 986 0.106666667 0.05 -1.093109404 Down 0.161175674 Cd164l2 CD164 sialomucin-like 2 K10104|1|5e-56|220|cjc:100390159|ficolin;K06546|2|7e-13|77.0|cmk:103179454|CD164 antigen GO:0031224//intrinsic component of membrane - - gi|115511040|ref|NP_081428.1|/1.1962e-73/CD164 sialomucin-like 2 protein precursor [Mus musculus] 18213 3847 0.06 0.123333333 1.039528364 Up 0.161175674 Ntrk3 "neurotrophic tyrosine kinase, receptor, type 3" "K05101|1|0.0|1153|myd:102761142|neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]" GO:0016021//integral component of membrane;GO:0044424;GO:0016021//integral component of membrane;GO:0044424 GO:0004713//protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0038023//signaling receptor activity;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0038023//signaling receptor activity;GO:0032550;GO:0019838//growth factor binding GO:0010467//gene expression;GO:0050918//positive chemotaxis;GO:0031532//actin cytoskeleton reorganization;GO:0032147//activation of protein kinase activity;GO:0051384//response to glucocorticoid;GO:0001708//cell fate specification;GO:0045686//negative regulation of glial cell differentiation;GO:0016477//cell migration;GO:0008219//cell death;GO:0008283//cell proliferation;GO:0019054//modulation by virus of host process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0097305//response to alcohol;GO:0032526//response to retinoic acid;GO:0009611//response to wounding;GO:0045773//positive regulation of axon extension;GO:0010467//gene expression;GO:0050918//positive chemotaxis;GO:0031532//actin cytoskeleton reorganization;GO:0032147//activation of protein kinase activity;GO:0051384//response to glucocorticoid;GO:0001708//cell fate specification;GO:0045686//negative regulation of glial cell differentiation;GO:0016477//cell migration;GO:0008219//cell death;GO:0008283//cell proliferation;GO:0019054//modulation by virus of host process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0097305//response to alcohol;GO:0032526//response to retinoic acid;GO:0009611//response to wounding;GO:0045773//positive regulation of axon extension gi|33413429|ref|NP_877961.1|/0/NT-3 growth factor receptor isoform b precursor [Mus musculus] 100503794 935 0.053333333 0.113333333 1.087462841 Up 0.161175674 Gm9920 predicted gene 9920 - - - - - 74725 1870 0.11 0.053333333 -1.044394119 Down 0.161175674 4930524B17Rik RIKEN cDNA 4930524B17 gene - - - - - 73707 3889 0.053333333 0.116666667 1.129283017 Up 0.161175674 Gucy2g guanylate cyclase 2g K12323|1|1e-180|636|sko:100378417|atrial natriuretic peptide receptor A [EC:4.6.1.2] - - - - 320749 3640 0.056666667 0.116666667 1.041820176 Up 0.161175674 D630041G03Rik RIKEN cDNA D630041G03 gene K17277|1|6e-24|116|ptg:102964906|epidermal growth factor receptor kinase substrate 8 GO:0044424 - - gi|351710552|gb|EHB13471.1|/2.6198e-29/Epidermal growth factor receptor kinase substrate 8-like protein 1 [Heterocephalus glaber] 211135 2002 0.053333333 0.113333333 1.087462841 Up 0.161175674 D130040H23Rik RIKEN cDNA D130040H23 gene K09228|1|3e-180|634|mmu:628709|KRAB domain-containing zinc finger protein - - - "gi|148696788|gb|EDL28735.1|/0/RIKEN cDNA D130040H23, isoform CRA_c, partial [Mus musculus]" 17389 4747 0.123333333 0.06 -1.039528364 Down 0.161175674 Mmp16 matrix metallopeptidase 16 K07996|1|0.0|787|lve:103087575|matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-] GO:0031012//extracellular matrix;GO:0031224//intrinsic component of membrane;GO:0031012//extracellular matrix;GO:0031224//intrinsic component of membrane GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0019538//protein metabolic process;GO:0032963//collagen metabolic process;GO:0019538//protein metabolic process;GO:0032963//collagen metabolic process gi|466040332|ref|XP_004276191.1|/0/PREDICTED: matrix metalloproteinase-16 [Orcinus orca] 100038374 874 0.12 0.056666667 -1.08246216 Down 0.161175674 Gm10714 predicted gene 10714 - - - - gi|74187787|dbj|BAE24544.1|/4.56682e-47/unnamed protein product [Mus musculus] 20195 504 110.3666667 113.2533333 0.037249003 Up 0.161109857 S100a11 S100 calcium binding protein A11 K17274|1|6e-17|88.6|ola:101155699|calpactin-1 light chain GO:0031981//nuclear lumen GO:0042802//identical protein binding;GO:0046872//metal ion binding GO:0048232//male gamete generation gi|21886811|ref|NP_058020.1|/1.22426e-49/protein S100-A11 [Mus musculus] 22637 1343 0.113333333 0.186666667 0.719892081 Up 0.161100455 Zap70 zeta-chain (TCR) associated protein kinase K07360|1|0.0|1234|mmu:22637|tyrosine-protein kinase ZAP-70 [EC:2.7.10.2] GO:0043235//receptor complex;GO:0044459;GO:0044444//cytoplasmic part;GO:0043235//receptor complex;GO:0044459;GO:0044444//cytoplasmic part GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0045309//protein phosphorylated amino acid binding;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0045309//protein phosphorylated amino acid binding GO:0050851//antigen receptor-mediated signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0006468//protein phosphorylation;GO:0043368//positive T cell selection;GO:0033077//T cell differentiation in thymus;GO:0019722//calcium-mediated signaling;GO:0045582//positive regulation of T cell differentiation;GO:0043383//negative T cell selection;GO:0050851//antigen receptor-mediated signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0006468//protein phosphorylation;GO:0043368//positive T cell selection;GO:0033077//T cell differentiation in thymus;GO:0019722//calcium-mediated signaling;GO:0045582//positive regulation of T cell differentiation;GO:0043383//negative T cell selection gi|577019559|ref|NP_001276695.1|/0/tyrosine-protein kinase ZAP-70 isoform b [Mus musculus] 228993 2197 0.223333333 0.3 0.425763906 Up 0.161100455 Slc17a9 "solute carrier family 17, member 9" "K12303|1|0.0|868|mmu:228993|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 9" GO:0031224//intrinsic component of membrane - GO:0016192//vesicle-mediated transport;GO:0044763 gi|125347351|ref|NP_898984.3|/0/solute carrier family 17 member 9 [Mus musculus] 83490 2615 0.853333333 0.976666667 0.194756854 Up 0.16092181 Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 K12230|1|0.0|1528|mmu:83490|phosphoinositide 3-kinase adapter protein 1 GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding - gi|13878195|ref|NP_113553.1|/0/phosphoinositide 3-kinase adapter protein 1 [Mus musculus] 208718 3161.93 6.663333333 6.363333333 -0.066461369 Down 0.160903005 Dis3l2 DIS3 like 3'-5' exoribonuclease 2 K18758|1|0.0|1623|mmu:208718|DIS3-like exonuclease 2 [EC:3.1.13.-] - - - - 71393 1666.65 6.263333333 6.563333333 0.067498044 Up 0.160903005 Kctd6 potassium channel tetramerisation domain containing 6 "K03849|1|7e-29|131|cmk:103177229|alpha-1,3-glucosyltransferase [EC:2.4.1.265];K20131|2|4e-14|82.4|bacu:103015608|Rab5 GDP/GTP exchange factor" - - - gi|823429575|ref|XP_012422084.1|/7.7153e-141/PREDICTED: BTB/POZ domain-containing protein KCTD6 isoform X1 [Odobenus rosmarus divergens] 12224 1728 0.173333333 0.106666667 -0.700439718 Down 0.160874798 Klf5 Kruppel-like factor 5 K09206|1|0.0|845|mmu:12224|krueppel-like factor 5 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0007519//skeletal muscle tissue development;GO:0006351//transcription, DNA-templated;GO:0030031//cell projection assembly" "gi|148668134|gb|EDL00464.1|/0/Kruppel-like factor 5, isoform CRA_a, partial [Mus musculus]" 18992 6272 0.106666667 0.173333333 0.700439718 Up 0.160874798 Pou3f2 "POU domain, class 3, transcription factor 2" "K09365|1|0.0|654|rno:29588|POU domain transcription factor, class 3" GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001104//RNA polymerase II transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0019904//protein domain specific binding;GO:0003677//DNA binding GO:0009888//tissue development;GO:0014044//Schwann cell development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007409//axonogenesis;GO:0010033//response to organic substance;GO:0021983//pituitary gland development;GO:0021846//cell proliferation in forebrain;GO:0021854//hypothalamus development;GO:0035264//multicellular organism growth;GO:0021795//cerebral cortex cell migration "gi|6679423|ref|NP_032925.1|/0/POU domain, class 3, transcription factor 2 [Mus musculus]" 16979 3756 0.19 0.116666667 -0.703606997 Down 0.160874798 Lrrn1 "leucine rich repeat protein 1, neuronal" K07523|1|7e-38|162|bfo:BRAFLDRAFT_64092|netrin-G1 ligand;K16351|3|2e-37|160|sko:100378039|netrin-G2 ligand GO:0031224//intrinsic component of membrane - - gi|50510957|dbj|BAD32464.1|/0/mKIAA1497 protein [Mus musculus] 13445 1283 94.8 97.49333333 0.040416511 Up 0.160865395 Cdk2ap1 CDK2 (cyclin-dependent kinase 2)-associated protein 1 K17868|1|2e-06|56.2|loa:LOAG_04022|diphthine methyl ester acylhydrolase [EC:3.1.1.97] GO:0043231//intracellular membrane-bounded organelle "GO:0003676//nucleic acid binding;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006260//DNA replication;GO:0009653//anatomical structure morphogenesis;GO:0006464//cellular protein modification process "gi|119618804|gb|EAW98398.1|/2.94653e-57/CDK2-associated protein 1, isoform CRA_a, partial [Homo sapiens]" 320478 2998 0.303333333 0.226666667 -0.420331799 Down 0.160846591 Sox2ot SOX2 overlapping transcript (non-protein coding) - - - - - 78284 1476 0.24 0.32 0.415037499 Up 0.160846591 Creb3l4 cAMP responsive element binding protein 3-like 4 K09048|1|2e-175|618|mmu:78284|cyclic AMP-responsive element-binding protein 3 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006366//transcription from RNA polymerase II promoter;GO:0035966//response to topologically incorrect protein;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006366//transcription from RNA polymerase II promoter;GO:0035966//response to topologically incorrect protein;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006366//transcription from RNA polymerase II promoter;GO:0035966//response to topologically incorrect protein gi|755504710|ref|XP_006502373.2|/0/PREDICTED: cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X2 [Mus musculus] 69571 1107 0.226666667 0.303333333 0.420331799 Up 0.160846591 2310034O05Rik RIKEN cDNA 2310034O05 gene - - - - gi|148688352|gb|EDL20299.1|/1.16218e-14/mCG147648 [Mus musculus] 57442 816 0.326666667 0.243333333 -0.424885285 Down 0.160846591 Kcne3 "potassium voltage-gated channel, Isk-related subfamily, gene 3" K04897|1|2e-54|215|mmu:57442|potassium voltage-gated channel Isk-related subfamily E member 3 GO:0005887//integral component of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005887//integral component of plasma membrane GO:0005267//potassium channel activity;GO:0016247//channel regulator activity;GO:0005267//potassium channel activity;GO:0016247//channel regulator activity;GO:0005267//potassium channel activity;GO:0016247//channel regulator activity;GO:0005267//potassium channel activity;GO:0016247//channel regulator activity;GO:0005267//potassium channel activity;GO:0016247//channel regulator activity GO:0034220//ion transmembrane transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0006813//potassium ion transport gi|10181220|ref|NP_065599.1|/9.83648e-54/potassium voltage-gated channel subfamily E member 3 [Mus musculus] 333473 2613 0.226666667 0.303333333 0.420331799 Up 0.160846591 Zfp36l3 "zinc finger protein 36, C3H type-like 3" K18753|1|8e-73|278|cge:103162508|butyrate response factor 1 GO:0044424 GO:0003723//RNA binding "GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" "gi|57222290|ref|NP_001009549.1|/1.97453e-161/zinc finger protein 36, C3H1 type-like 3 [Mus musculus]" 16155 1878 92.14666667 89.57666667 -0.040808997 Down 0.160696153 Il10rb "interleukin 10 receptor, beta" K05135|1|0.0|678|mmu:16155|interleukin 10 receptor beta GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0007166//cell surface receptor signaling pathway gi|111607428|ref|NP_032375.2|/0/interleukin-10 receptor subunit beta precursor [Mus musculus] 20743 8254 0.186666667 0.116666667 -0.678071905 Down 0.160667945 Sptbn2 "spectrin beta, non-erythrocytic 2" K06115|1|0.0|4215|mmu:20743|spectrin beta GO:0034399//nuclear periphery;GO:0044297//cell body;GO:0030864//cortical actin cytoskeleton GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0008289//lipid binding GO:0009653//anatomical structure morphogenesis;GO:0040007//growth;GO:0030835//negative regulation of actin filament depolymerization;GO:0017156//calcium ion regulated exocytosis;GO:0006904//vesicle docking involved in exocytosis;GO:0007399//nervous system development "gi|55926127|ref|NP_067262.1|/0/spectrin beta chain, non-erythrocytic 2 [Mus musculus]" 319207 3243 0.186666667 0.116666667 -0.678071905 Down 0.160667945 Pgbd1 piggyBac transposable element derived 1 K10841|1|6e-53|144|rro:104677713|DNA excision repair protein ERCC-6 - - - "gi|148700707|gb|EDL32654.1|/0/RIKEN cDNA 4921509E05, isoform CRA_a, partial [Mus musculus]" 53881 10918 0.12 0.193333333 0.688055994 Up 0.160667945 Slc5a3 "solute carrier family 5 (inositol transporters), member 3" "K14383|1|0.0|1367|mmu:53881|solute carrier family 5 (sodium/myo-inositol cotransporter), member 3" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0044763;GO:0019751//polyol metabolic process;GO:0007585//respiratory gaseous exchange;GO:0015791//polyol transport;GO:0007399//nervous system development;GO:0030001//metal ion transport gi|148536859|ref|NP_059087.2|/0/sodium/myo-inositol cotransporter [Mus musculus] 432825 1004 0.12 0.193333333 0.688055994 Up 0.160667945 Gm5458 predicted gene 5458 "K03844|1|3e-18|94.7|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - gi|755547122|ref|XP_011243088.1|/6.45746e-101/PREDICTED: uncharacterized protein Gm3050 isoform X3 [Mus musculus] 353156 1386.43 92.21333333 89.69 -0.040028228 Down 0.160592726 Egfl7 EGF-like domain 7 K02599|1|6e-14|81.3|ptg:102970846|Notch;K06824|4|7e-13|77.8|tgu:100230214|nephronectin GO:0044421;GO:0044421;GO:0044421;GO:0044421 GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0048646//anatomical structure formation involved in morphogenesis;GO:0016477//cell migration;GO:0001944//vasculature development;GO:0048869//cellular developmental process;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0016477//cell migration;GO:0001944//vasculature development;GO:0048869//cellular developmental process;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0016477//cell migration;GO:0001944//vasculature development;GO:0048869//cellular developmental process;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0016477//cell migration;GO:0001944//vasculature development;GO:0048869//cellular developmental process gi|257096010|ref|NP_848538.3|/6.97047e-159/epidermal growth factor-like protein 7 isoform 1 precursor [Mus musculus] 18242 2155 85.54666667 88.05 0.041611363 Up 0.160583324 Oat ornithine aminotransferase K00819|1|0.0|845|mmu:18242|ornithine--oxo-acid transaminase [EC:2.6.1.13] GO:0044429 GO:0043168//anion binding;GO:0008483//transaminase activity GO:0051259//protein oligomerization;GO:0006561//proline biosynthetic process "gi|8393866|ref|NP_058674.1|/0/ornithine aminotransferase, mitochondrial precursor [Mus musculus]" 30795 945 84.96 82.48666667 -0.042622828 Down 0.160573922 Fkbp3 FK506 binding protein 3 K09570|1|8e-120|432|mmu:30795|FK506-binding protein 3 [EC:5.2.1.8] GO:0043231//intracellular membrane-bounded organelle GO:0016859//cis-trans isomerase activity;GO:0005527//macrolide binding GO:0018208//peptidyl-proline modification "gi|148704701|gb|EDL36648.1|/7.13103e-121/FK506 binding protein 3, isoform CRA_a, partial [Mus musculus]" 213550 3530.77 16.26 15.67666667 -0.052708426 Down 0.160573922 Dis3l DIS3 like exosome 3'-5' exoribonuclease K18681|1|0.0|1999|mmu:213550|DIS3-like exonuclease 1 [EC:3.1.13.-] - - - - 108112 1151 2.886666667 2.696666667 -0.098227322 Down 0.160479898 Eif4ebp3 eukaryotic translation initiation factor 4E binding protein 3 K18645|1|4e-54|214|mmu:108112|eukaryotic translation initiation factor 4E binding protein 3 - GO:0031369//translation initiation factor binding GO:0006413//translational initiation gi|41054842|ref|NP_957708.1|/2.99753e-53/eukaryotic translation initiation factor 4E-binding protein 3 [Mus musculus] 74173 1073 2.566666667 2.76 0.104772322 Up 0.160479898 Rab10os "RAB10, member RAS oncogene family, opposite strand" K06287|1|9e-09|63.5|mmu:69099|septum formation protein - - - - 223732 4447 2.75 2.56 -0.103287808 Down 0.160479898 Ldoc1l "leucine zipper, down-regulated in cancer 1-like" - - - - gi|110681693|ref|NP_808298.2|/2.68208e-132/protein LDOC1L [Mus musculus] 12372 1874 4.55 4.31 -0.078178676 Down 0.160442288 Casq1 calsequestrin 1 K01539|1|2e-125|452|fch:102059303|sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9];K09582|3|4e-09|65.9|gga:420785|protein disulfide-isomerase A4 [EC:5.3.4.1];K09580|4|5e-09|65.5|lgi:LOTGIDRAFT_184255|protein disulfide-isomerase A1 [EC:5.3.4.1] GO:0014802//terminal cisterna;GO:0005788//endoplasmic reticulum lumen;GO:0042383//sarcolemma;GO:0030017//sarcomere GO:0046872//metal ion binding GO:0042221//response to chemical;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0014706//striated muscle tissue development;GO:0006936//muscle contraction;GO:0014877;GO:0006996//organelle organization;GO:0006950//response to stress gi|227430322|ref|NP_033943.2|/0/calsequestrin-1 precursor [Mus musculus] 319710 4695 4.36 4.123333333 -0.080517041 Down 0.160442288 Frmd6 FERM domain containing 6 K16822|1|0.0|1100|mmu:319710|FERM domain-containing protein 6 GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0043232 - GO:0030029//actin filament-based process;GO:0008104//protein localization "gi|148704624|gb|EDL36571.1|/0/FERM domain containing 6, isoform CRA_b, partial [Mus musculus]" 16780 4016 4.16 4.396666667 0.07982663 Up 0.160442288 Lamb3 "laminin, beta 3" "K06244|1|0.0|2163|mmu:16780|laminin, beta 3" GO:0043256//laminin complex;GO:0043256//laminin complex GO:0005515//protein binding;GO:0005515//protein binding GO:0045444//fat cell differentiation;GO:0022610;GO:0045444//fat cell differentiation;GO:0022610 gi|113865981|ref|NP_032510.2|/0/laminin subunit beta-3 precursor [Mus musculus] 70052 5237 4.793333333 4.55 -0.075162725 Down 0.160442288 Prpf4 pre-mRNA processing factor 4 K12662|1|0.0|1011|cge:100753511|U4/U6 small nuclear ribonucleoprotein PRP4 - - - - 12822 5136.26 4.43 4.19 -0.080356455 Down 0.160442288 Col18a1 "collagen, type XVIII, alpha 1" "K06823|1|0.0|1138|mmu:12822|collagen, type XVIII, alpha" GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix GO:0005515//protein binding;GO:0005515//protein binding GO:0016477//cell migration;GO:0043062//extracellular structure organization;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0001885//endothelial cell development;GO:0006915//apoptotic process;GO:0050794//regulation of cellular process;GO:0008283//cell proliferation;GO:0016477//cell migration;GO:0043062//extracellular structure organization;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0001885//endothelial cell development;GO:0006915//apoptotic process;GO:0050794//regulation of cellular process;GO:0008283//cell proliferation gi|158508560|ref|NP_001103461.1|/0/collagen alpha-1(XVIII) chain isoform 1 precursor [Mus musculus] 54409 872 96.27666667 93.90666667 -0.035958611 Down 0.160404679 Ramp2 receptor (calcitonin) activity modifying protein 2 K08448|1|3e-98|360|mmu:54409|receptor activity modifying protein 2 GO:0044424;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex GO:0005102//receptor binding;GO:0038023//signaling receptor activity;GO:0046983//protein dimerization activity;GO:0022892//substrate-specific transporter activity GO:0001525//angiogenesis;GO:0044703;GO:0007186//G-protein coupled receptor signaling pathway;GO:0071363//cellular response to growth factor stimulus;GO:0007043//cell-cell junction assembly;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0006898//receptor-mediated endocytosis;GO:0007009//plasma membrane organization;GO:0015031//protein transport;GO:0043627//response to estrogen;GO:0006171//cAMP biosynthetic process;GO:0070838//divalent metal ion transport;GO:0006950//response to stress;GO:0055001//muscle cell development;GO:0043114//regulation of vascular permeability;GO:0001570//vasculogenesis gi|9507029|ref|NP_062317.1|/2.80226e-97/receptor activity-modifying protein 2 precursor [Mus musculus] 217149 750 81.47333333 79.10666667 -0.042528653 Down 0.160404679 Cisd3 CDGSH iron sulfur domain 3 - GO:0043231//intracellular membrane-bounded organelle GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding - "gi|168229148|ref|NP_001078969.2|/6.36295e-78/CDGSH iron-sulfur domain-containing protein 3, mitochondrial precursor [Mus musculus]" 107686 508 88.47 90.75666667 0.036815299 Up 0.160301252 Snrpd2 small nuclear ribonucleoprotein D2 K11096|1|1e-52|207|ptg:102969645|small nuclear ribonucleoprotein D2 GO:0005681//spliceosomal complex;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen GO:0097159//organic cyclic compound binding "GO:0000398//mRNA splicing, via spliceosome" gi|961731556|ref|XP_014926202.1|/2.07252e-52/PREDICTED: small nuclear ribonucleoprotein Sm D2 [Acinonyx jubatus] 56424 1672 77.84 80.06333333 0.040629972 Up 0.16025424 Stub1 STIP1 homology and U-Box containing protein 1 K09561|1|2e-156|554|mmu:56424|STIP1 homology and U-box containing protein 1 [EC:2.3.2.27] GO:0016234//inclusion body;GO:0043234//protein complex GO:0044389//ubiquitin-like protein ligase binding;GO:0031072//heat shock protein binding;GO:0019904//protein domain specific binding;GO:0004842//ubiquitin-protein transferase activity;GO:0042802//identical protein binding GO:0035967//cellular response to topologically incorrect protein;GO:0000209//protein polyubiquitination;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0010467//gene expression;GO:0006259//DNA metabolic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0031334//positive regulation of protein complex assembly;GO:0031331;GO:0008211//glucocorticoid metabolic process gi|9789907|ref|NP_062693.1|/2.07932e-155/STIP1 homology and U box-containing protein 1 [Mus musculus] 102193 2874 16.87666667 17.44333333 0.047645775 Up 0.160216631 Zdhhc7 "zinc finger, DHHC domain containing 7" K20029|1|2e-163|578|mmu:102193|palmitoyltransferase ZDHHC3/7/25 [EC:2.3.1.225] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0046914//transition metal ion binding" GO:0018231;GO:0006497//protein lipidation "gi|148679679|gb|EDL11626.1|/2.76953e-180/zinc finger, DHHC domain containing 7, isoform CRA_a [Mus musculus]" 70788 3020 17.76 18.32666667 0.045312824 Up 0.160216631 Klhl30 kelch-like 30 K10466|1|0.0|1196|mmu:70788|kelch-like protein 30 - - - gi|58037217|ref|NP_081827.1|/0/kelch-like protein 30 [Mus musculus] 14860 970 89.23666667 87.04333333 -0.035902819 Down 0.160197826 Gsta4 "glutathione S-transferase, alpha 4" K00799|1|1e-112|408|mmu:14860|glutathione S-transferase [EC:2.5.1.18] - - - - 18761 3313 1.68 1.53 -0.13492958 Down 0.160019181 Prkcq "protein kinase C, theta" K18052|1|0.0|1452|mmu:18761|novel protein kinase C theta type [EC:2.7.11.13] GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0045202//synapse;GO:0044444//cytoplasmic part GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0005515//protein binding;GO:0043169//cation binding GO:0070229//negative regulation of lymphocyte apoptotic process;GO:0010543//regulation of platelet activation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0042094//interleukin-2 biosynthetic process;GO:0022411;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006952//defense response;GO:0006796//phosphate-containing compound metabolic process;GO:0016049//cell growth;GO:0035712//T-helper 2 cell activation;GO:0031346//positive regulation of cell projection organization;GO:0006935//chemotaxis;GO:0001819//positive regulation of cytokine production;GO:0032233//positive regulation of actin filament bundle assembly;GO:0033619//membrane protein proteolysis;GO:0006464//cellular protein modification process;GO:0002824;GO:0000086//G2/M transition of mitotic cell cycle;GO:0042098//T cell proliferation;GO:0009306//protein secretion;GO:0008286//insulin receptor signaling pathway;GO:0042345//regulation of NF-kappaB import into nucleus gi|6679353|ref|NP_032885.1|/0/protein kinase C theta type [Mus musculus] 52397 5700 1.726666667 1.576666667 -0.131111914 Down 0.160019181 Zfp644 zinc finger protein 644 K09228|1|5e-14|84.0|ngi:103725454|KRAB domain-containing zinc finger protein GO:0044464 GO:0046914//transition metal ion binding - gi|51988896|ref|NP_081132.2|/0/zinc finger protein 644 [Mus musculus] 414066 4622 1.843333333 1.69 -0.125293733 Down 0.160019181 BC037032 cDNA Sequence BC037032 - - - - - 76857 2761 1.76 1.613333333 -0.125530882 Down 0.160019181 Spopl speckle-type POZ protein-like K10523|1|0.0|802|mmu:76857|speckle-type POZ protein GO:0031461//cullin-RING ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle - GO:0016567//protein ubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process gi|532005144|ref|XP_005346434.1|/0/PREDICTED: speckle-type POZ protein-like isoform X1 [Microtus ochrogaster] 234733 6639 1.586666667 1.74 0.133088233 Up 0.160019181 Ddx19b DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b K18655|1|0.0|920|mmu:234733|ATP-dependent RNA helicase DDX19/DBP5 [EC:3.6.4.13] GO:0005635//nuclear envelope;GO:0005635//nuclear envelope "GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0042623//ATPase activity, coupled" GO:0045184//establishment of protein localization;GO:0006405//RNA export from nucleus;GO:0045184//establishment of protein localization;GO:0006405//RNA export from nucleus "gi|148679535|gb|EDL11482.1|/0/mCG133615, isoform CRA_b, partial [Mus musculus]" 14566 1805 0.193333333 0.123333333 -0.648527629 Down 0.159981571 Gdf9 growth differentiation factor 9 K05498|1|0.0|866|mmu:14566|growth differentiation factor 9/9B GO:0044421 GO:0005102//receptor binding GO:0032368//regulation of lipid transport;GO:0016049//cell growth;GO:0003006//developmental process involved in reproduction;GO:0008283//cell proliferation gi|160298182|ref|NP_032136.2|/0/growth/differentiation factor 9 precursor [Mus musculus] 622434 5205 0.613333333 0.516666667 -0.247437551 Down 0.159972169 Arhgef26 Rho guanine nucleotide exchange factor (GEF) 26 K13744|1|0.0|1661|mmu:622434|Rho guanine nucleotide exchange factor 26 GO:0044464 GO:0008289//lipid binding GO:0007266//Rho protein signal transduction gi|124486829|ref|NP_001074764.1|/0/rho guanine nucleotide exchange factor 26 [Mus musculus] 170441 3434 0.536666667 0.64 0.254045623 Up 0.159972169 Slc2a10 "solute carrier family 2 (facilitated glucose transporter), member 10" "K08147|1|0.0|848|mmu:170441|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 10" - - - - 67046 1257.02 15.13666667 15.69666667 0.052410686 Up 0.15989695 Tbc1d7 "TBC1 domain family, member 7" K20396|1|4e-169|596|mmu:67046|TBC1 domain family member 7 GO:0031982//vesicle;GO:0044464;GO:0031982//vesicle;GO:0044464;GO:0031982//vesicle;GO:0044464 - GO:0010033//response to organic substance;GO:0009968//negative regulation of signal transduction;GO:0016567//protein ubiquitination;GO:0010033//response to organic substance;GO:0009968//negative regulation of signal transduction;GO:0016567//protein ubiquitination;GO:0010033//response to organic substance;GO:0009968//negative regulation of signal transduction;GO:0016567//protein ubiquitination gi|21313148|ref|NP_080211.1|/3.24115e-168/TBC1 domain family member 7 isoform 1 [Mus musculus] 77371 6796.48 2.083333333 1.923333333 -0.115284871 Down 0.159840536 Sec24a "Sec24 related gene family, member A (S. cerevisiae)" K14007|1|0.0|1940|mmu:77371|protein transport protein SEC24 GO:0012507//ER to Golgi transport vesicle membrane;GO:0012507//ER to Golgi transport vesicle membrane GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0016482//cytosolic transport;GO:0015031//protein transport;GO:0016482//cytosolic transport;GO:0015031//protein transport gi|116174774|ref|NP_780464.2|/0/protein transport protein Sec24A isoform 1 [Mus musculus] 72748 1098 1.833333333 1.993333333 0.120713866 Up 0.159840536 Hdhd3 haloacid dehalogenase-like hydrolase domain containing 3 K01698|1|7e-57|223|fpg:101919461|porphobilinogen synthase [EC:4.2.1.24] GO:0043231//intracellular membrane-bounded organelle GO:0016791//phosphatase activity - gi|21312204|ref|NP_077219.1|/8.21323e-130/haloacid dehalogenase-like hydrolase domain-containing protein 3 [Mus musculus] 73668 4470 1.956666667 1.796666667 -0.12307523 Down 0.159840536 Ttc21b tetratricopeptide repeat domain 21B K19673|1|0.0|2502|mmu:73668|tetratricopeptide repeat protein 21B - - - - 19181 1782 65.92666667 67.97666667 0.04417748 Up 0.159831133 Psmc2 "proteasome (prosome, macropain) 26S subunit, ATPase 2" K03061|1|0.0|880|mmu:19181|26S proteasome regulatory subunit T1 GO:0031981//nuclear lumen;GO:0000502//proteasome complex;GO:0035770//ribonucleoprotein granule;GO:0044444//cytoplasmic part GO:0008134//transcription factor binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 "GO:0006915//apoptotic process;GO:0006520//cellular amino acid metabolic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0044772//mitotic cell cycle phase transition;GO:0009154//purine ribonucleotide catabolic process;GO:0016070//RNA metabolic process;GO:0051320;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle" gi|33859604|ref|NP_035318.1|/0/26S protease regulatory subunit 7 [Mus musculus] 12048 2554.1 75.82333333 77.86333333 0.038302226 Up 0.159812328 Bcl2l1 BCL2-like 1 K04570|1|5e-92|340|rno:24888|Bcl-2-like 1 (apoptosis regulator Bcl-X) GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0031966//mitochondrial membrane;GO:0005635//nuclear envelope;GO:0005815//microtubule organizing center;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0031966//mitochondrial membrane;GO:0005635//nuclear envelope;GO:0005815//microtubule organizing center;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0031966//mitochondrial membrane;GO:0005635//nuclear envelope;GO:0005815//microtubule organizing center GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0051400//BH domain binding;GO:0019900//kinase binding;GO:0046983//protein dimerization activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0051400//BH domain binding;GO:0019900//kinase binding;GO:0046983//protein dimerization activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0051400//BH domain binding;GO:0019900//kinase binding;GO:0046983//protein dimerization activity GO:0000075//cell cycle checkpoint;GO:0006914//autophagy;GO:0010332//response to gamma radiation;GO:0043009//chordate embryonic development;GO:0010823//negative regulation of mitochondrion organization;GO:0048232//male gamete generation;GO:0006952//defense response;GO:0042391//regulation of membrane potential;GO:0051726//regulation of cell cycle;GO:0097193//intrinsic apoptotic signaling pathway;GO:0043279//response to alkaloid;GO:0043200//response to amino acid;GO:0030522//intracellular receptor signaling pathway;GO:0000302//response to reactive oxygen species;GO:0010038//response to metal ion;GO:0008637//apoptotic mitochondrial changes;GO:0008283//cell proliferation;GO:0008585//female gonad development;GO:0006839//mitochondrial transport;GO:0043066//negative regulation of apoptotic process;GO:0051707//response to other organism;GO:0009725//response to hormone;GO:0000075//cell cycle checkpoint;GO:0006914//autophagy;GO:0010332//response to gamma radiation;GO:0043009//chordate embryonic development;GO:0010823//negative regulation of mitochondrion organization;GO:0048232//male gamete generation;GO:0006952//defense response;GO:0042391//regulation of membrane potential;GO:0051726//regulation of cell cycle;GO:0097193//intrinsic apoptotic signaling pathway;GO:0043279//response to alkaloid;GO:0043200//response to amino acid;GO:0030522//intracellular receptor signaling pathway;GO:0000302//response to reactive oxygen species;GO:0010038//response to metal ion;GO:0008637//apoptotic mitochondrial changes;GO:0008283//cell proliferation;GO:0008585//female gonad development;GO:0006839//mitochondrial transport;GO:0043066//negative regulation of apoptotic process;GO:0051707//response to other organism;GO:0009725//response to hormone;GO:0000075//cell cycle checkpoint;GO:0006914//autophagy;GO:0010332//response to gamma radiation;GO:0043009//chordate embryonic development;GO:0010823//negative regulation of mitochondrion organization;GO:0048232//male gamete generation;GO:0006952//defense response;GO:0042391//regulation of membrane potential;GO:0051726//regulation of cell cycle;GO:0097193//intrinsic apoptotic signaling pathway;GO:0043279//response to alkaloid;GO:0043200//response to amino acid;GO:0030522//intracellular receptor signaling pathway;GO:0000302//response to reactive oxygen species;GO:0010038//response to metal ion;GO:0008637//apoptotic mitochondrial changes;GO:0008283//cell proliferation;GO:0008585//female gonad development;GO:0006839//mitochondrial transport;GO:0043066//negative regulation of apoptotic process;GO:0051707//response to other organism;GO:0009725//response to hormone "gi|148674045|gb|EDL05992.1|/1.03066e-125/Bcl2-like 1, isoform CRA_c, partial [Mus musculus]" 77006 1101 70.09 68.05666667 -0.042472133 Down 0.159802926 Ddrgk1 DDRGK domain containing 1 K15437|1|2e-23|112|hro:HELRODRAFT_191890|aminoacyl tRNA synthase complex-interacting multifunctional protein 1 - - - gi|110350660|ref|NP_084108.1|/9.52745e-94/DDRGK domain-containing protein 1 precursor [Mus musculus] 18569 2116.86 5.713333333 6.003333333 0.071431072 Up 0.159765316 Pdcd4 programmed cell death 4 K16865|1|0.0|833|mmu:18569|programmed cell death protein 4 GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0005488//binding;GO:0005488//binding "GO:0006351//transcription, DNA-templated;GO:0012501//programmed cell death;GO:0007568//aging;GO:0043407//negative regulation of MAP kinase activity;GO:0006351//transcription, DNA-templated;GO:0012501//programmed cell death;GO:0007568//aging;GO:0043407//negative regulation of MAP kinase activity;GO:0006351//transcription, DNA-templated;GO:0012501//programmed cell death;GO:0007568//aging;GO:0043407//negative regulation of MAP kinase activity" "gi|148669763|gb|EDL01710.1|/0/programmed cell death 4, isoform CRA_a, partial [Mus musculus]" 11907 4772.29 5.906666667 5.62 -0.071774068 Down 0.159765316 Ate1 arginyltransferase 1 K00685|1|0.0|960|mmu:11907|arginine-tRNA-protein transferase [EC:2.3.2.8] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016740//transferase activity;GO:0016740//transferase activity;GO:0016740//transferase activity;GO:0016740//transferase activity GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process gi|71274127|ref|NP_001025066.1|/0/arginyl-tRNA--protein transferase 1 isoform 3 [Mus musculus] 66132 3117 3.34 3.553333333 0.08932493 Up 0.159708902 1110008L16Rik RIKEN cDNA 1110008L16 gene K17655|1|0.0|1180|mmu:66132|mitochondrial ribonuclease P protein 3 - - - - 73385 3863 3.553333333 3.343333333 -0.087885832 Down 0.159708902 Fam177a "family with sequence similarity 177, member A" K12400|1|3e-25|120|hgl:106007798|AP-4 complex subunit epsilon-1 - - - gi|37537562|ref|NP_082803.1|/9.16774e-89/protein FAM177A1 [Mus musculus] 71406 4086 3.133333333 3.34 0.092149847 Up 0.159708902 5430416O09Rik RIKEN cDNA 5430416O09 gene - - - - gi|149045771|gb|EDL98771.1|/2.13423e-42/rCG54821 [Rattus norvegicus] 75894 2424.01 3.556666667 3.343333333 -0.08923857 Down 0.159708902 Adal adenosine deaminase-like K01488|1|2e-29|133|phu:Phum_PHUM377770|adenosine deaminase [EC:3.5.4.4];K15451|2|7e-25|118|mmu:329504|tRNA wybutosine-synthesizing protein 4 [EC:2.1.1.290 2.3.1.231] - GO:0003824//catalytic activity GO:0006753//nucleoside phosphate metabolic process;GO:0034654 "gi|148696088|gb|EDL28035.1|/0/mCG11969, isoform CRA_b, partial [Mus musculus]" 192119 9851 3.32 3.113333333 -0.092723192 Down 0.159708902 Dicer1 "dicer 1, ribonuclease type III" K11592|1|0.0|3661|mmu:192119|endoribonuclease Dicer [EC:3.1.26.-] GO:0031332//RNAi effector complex "GO:0043169//cation binding;GO:0032550;GO:0003723//RNA binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0042623//ATPase activity, coupled" GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0016246//RNA interference "gi|148686840|gb|EDL18787.1|/0/Dicer1, Dcr-1 homolog (Drosophila), isoform CRA_a, partial [Mus musculus]" 107368 7076 3.35 3.14 -0.093396536 Down 0.159708902 Pdzd8 PDZ domain containing 8 K10360|1|4e-06|58.2|shr:100934293|myosin IX - GO:0043169//cation binding GO:0000902//cell morphogenesis;GO:0006996//organelle organization gi|164698472|ref|NP_001028394.2|/0/PDZ domain-containing protein 8 [Mus musculus] 69833 579 67.74 65.75 -0.043017092 Down 0.1596995 Polr2f polymerase (RNA) II (DNA directed) polypeptide F "K03014|1|8e-45|181|ssc:100524934|DNA-directed RNA polymerases I, II, and III subunit RPABC2" - - - - 434204 3069 8.143333333 8.516666667 0.064669428 Up 0.159596074 Whamm "WAS protein homolog associated with actin, golgi membranes and microtubules" "K20479|1|0.0|1377|mmu:434204|WASP homolog-associated protein with actin, membranes and microtubules" GO:0043231//intracellular membrane-bounded organelle - - gi|60359958|dbj|BAD90198.1|/0/mKIAA1971 protein [Mus musculus] 68055 1485 8.91 9.283333333 0.05921749 Up 0.159596074 Atp5s "ATP synthase, H+ transporting, mitochondrial F0 complex, subunit S" "K07554|1|1e-109|399|mmu:68055|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s" "GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0019866//organelle inner membrane" GO:0043169//cation binding GO:0006818//hydrogen transport;GO:0009152//purine ribonucleotide biosynthetic process "gi|148704654|gb|EDL36601.1|/2.42665e-112/ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s, isoform CRA_b, partial [Mus musculus]" 20437 2121 8.346666667 8.716666667 0.062576384 Up 0.159596074 Siah1a seven in absentia 1A K04506|1|1e-168|596|cge:100774026|E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27] GO:0016020//membrane;GO:0043234//protein complex;GO:0005768//endosome GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity GO:0048731//system development;GO:0070997//neuron death;GO:0031647//regulation of protein stability;GO:0097193//intrinsic apoptotic signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0006935//chemotaxis;GO:0048232//male gamete generation gi|151554393|gb|AAI49765.1|/2.13534e-171/Unknown (protein for IMAGE:8095756) [Bos taurus] 26378 2051 9.4 9.77 0.055697805 Up 0.159596074 Decr2 "2-4-dienoyl-Coenzyme A reductase 2, peroxisomal" "K13237|1|3e-155|551|mmu:26378|peroxisomal 2,4-dienoyl-CoA reductase [EC:1.3.1.34]" GO:0044439;GO:0030529//intracellular ribonucleoprotein complex "GO:0005198//structural molecule activity;GO:0032550;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0009209;GO:0010467//gene expression;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006633//fatty acid biosynthetic process "gi|6753622|ref|NP_036063.1|/2.97799e-154/peroxisomal 2,4-dienoyl-CoA reductase [Mus musculus]" 17131 4441 8.95 9.323333333 0.058958166 Up 0.159596074 Smad7 SMAD family member 7 K19631|1|0.0|646|mmu:17131|mothers against decapentaplegic homolog 7 GO:0019897//extrinsic component of plasma membrane;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0005911//cell-cell junction;GO:0044444//cytoplasmic part "GO:0005160//transforming growth factor beta receptor binding;GO:0032403//protein complex binding;GO:0000975//regulatory region DNA binding;GO:0046332//SMAD binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0005072//transforming growth factor beta receptor, cytoplasmic mediator activity" "GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0034405//response to fluid shear stress;GO:0032924//activin receptor signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0001933//negative regulation of protein phosphorylation;GO:0001837//epithelial to mesenchymal transition;GO:0016477//cell migration;GO:0031397//negative regulation of protein ubiquitination;GO:0031503//protein complex localization;GO:0030509//BMP signaling pathway;GO:0003281//ventricular septum development;GO:0006942//regulation of striated muscle contraction;GO:0034329//cell junction assembly;GO:0003254//regulation of membrane depolarization;GO:0044092//negative regulation of molecular function;GO:0048514//blood vessel morphogenesis;GO:0031331;GO:0031647//regulation of protein stability;GO:0003208//cardiac ventricle morphogenesis" "gi|149027134|gb|EDL82858.1|/0/MAD homolog 7 (Drosophila), isoform CRA_a [Rattus norvegicus]" 70021 1435 16.96666667 16.41666667 -0.047541932 Down 0.159549062 Nt5dc2 5'-nucleotidase domain containing 2 K01081|1|2e-36|155|cin:100183021|5'-nucleotidase [EC:3.1.3.5] - GO:0043169//cation binding - gi|568988697|ref|XP_006519570.1|/0/PREDICTED: 5'-nucleotidase domain-containing protein 2 isoform X1 [Mus musculus] 71900 6099 15.32666667 15.88 0.051166947 Up 0.159549062 Tmem106b transmembrane protein 106B - GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0005770//late endosome - - gi|188035856|ref|NP_082268.2|/3.40138e-141/transmembrane protein 106B [Mus musculus] 230674 4601.05 16.63333333 16.08 -0.048809908 Down 0.159549062 Kdm4a lysine (K)-specific demethylase 4A K06709|1|0.0|1993|mmu:230674|jumonji domain-containing protein 2 [EC:1.14.11.-] - - - gi|240120087|ref|NP_759014.2|/0/lysine-specific demethylase 4A isoform 2 [Mus musculus] 102060 1734 62.04333333 63.97666667 0.044269628 Up 0.15950205 Gadd45gip1 "growth arrest and DNA-damage-inducible, gamma interacting protein 1" - - - - - 319322 3249 76.42333333 74.51333333 -0.036514582 Down 0.159426831 Sf3b2 "splicing factor 3b, subunit 2" K12829|1|0.0|1166|mmu:319322|splicing factor 3B subunit 2 GO:0005681//spliceosomal complex - - gi|268837785|ref|NP_084385.2|/0/splicing factor 3B subunit 2 [Mus musculus] 12351 1316 61.77 63.66666667 0.043631902 Up 0.159417428 Car4 carbonic anhydrase 4 K18246|1|2e-162|574|mmu:12351|carbonic anhydrase 4 [EC:4.2.1.1] GO:0030141//secretory granule;GO:0030133//transport vesicle;GO:0005903//brush border;GO:0046658//anchored component of plasma membrane;GO:0005783//endoplasmic reticulum GO:0046914//transition metal ion binding;GO:0016836//hydro-lyase activity GO:0048731//system development;GO:0009725//response to hormone;GO:0015711//organic anion transport;GO:0044237//cellular metabolic process gi|74185883|dbj|BAE32805.1|/2.39684e-176/unnamed protein product [Mus musculus] 52551 1966 73.4 71.52 -0.037433327 Down 0.159323404 Sgta "small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha" K16365|1|2e-165|585|mmu:52551|small glutamine-rich tetratricopeptide repeat-containing protein alpha GO:0044424 - - gi|564358292|ref|XP_006241058.1|/4.65489e-169/PREDICTED: small glutamine-rich tetratricopeptide repeat-containing protein alpha isoform X1 [Rattus norvegicus] 59008 2774.89 75.82 73.95 -0.036028309 Down 0.1593046 Anapc5 anaphase-promoting complex subunit 5 K03352|1|0.0|1382|mmu:59008|anaphase-promoting complex subunit 5 GO:0000152//nuclear ubiquitin ligase complex;GO:0000152//nuclear ubiquitin ligase complex;GO:0000152//nuclear ubiquitin ligase complex;GO:0000152//nuclear ubiquitin ligase complex;GO:0000152//nuclear ubiquitin ligase complex;GO:0000152//nuclear ubiquitin ligase complex GO:0019902//phosphatase binding;GO:0019902//phosphatase binding;GO:0019902//phosphatase binding;GO:0019902//phosphatase binding;GO:0019902//phosphatase binding;GO:0019902//phosphatase binding GO:0000209//protein polyubiquitination;GO:0000087//mitotic M phase;GO:0000209//protein polyubiquitination;GO:0000087//mitotic M phase;GO:0000209//protein polyubiquitination;GO:0000087//mitotic M phase;GO:0000209//protein polyubiquitination;GO:0000087//mitotic M phase;GO:0000209//protein polyubiquitination;GO:0000087//mitotic M phase;GO:0000209//protein polyubiquitination;GO:0000087//mitotic M phase gi|575501610|ref|NP_001276447.1|/0/anaphase-promoting complex subunit 5 isoform d [Mus musculus] 69917 1106 60.79333333 62.63333333 0.043017536 Up 0.159238783 Nabp2 nucleic acid binding protein 2 "K15280|1|2e-36|155|tca:660868|solute carrier family 35, member C2;K14711|3|9e-07|55.5|fch:102056028|solute carrier family 39 (zinc transporter), member 5" GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0043566//structure-specific DNA binding GO:0009314//response to radiation;GO:0000725//recombinational repair gi|795335349|ref|XP_011781509.1|/9.24279e-84/PREDICTED: SOSS complex subunit B1 isoform X1 [Colobus angolensis palliatus] 64058 1901 67.94 66.1 -0.039610946 Down 0.159238783 Perp "PERP, TP53 apoptosis effector" K10136|1|2e-90|336|mmu:64058|TP53 apoptosis effector GO:0016021//integral component of membrane;GO:0031981//nuclear lumen - GO:0012502//induction of programmed cell death;GO:0016337//single organismal cell-cell adhesion;GO:0042475//odontogenesis of dentin-containing tooth;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0006508//proteolysis gi|11528520|ref|NP_071315.1|/1.36466e-89/p53 apoptosis effector related to PMP-22 [Mus musculus] 19265 853 0.48 0.39 -0.299560282 Down 0.159238783 Ptprcap "protein tyrosine phosphatase, receptor type, C polypeptide-associated protein" - - - - gi|18640746|ref|NP_058629.2|/3.80643e-51/protein tyrosine phosphatase receptor type C-associated protein precursor [Mus musculus] 100502888 2572 0.313333333 0.236666667 -0.404841732 Down 0.159182369 Gm19434 "predicted gene, 19434" - - - - gi|148678599|gb|EDL10546.1|/9.26422e-28/mCG1027124 [Mus musculus] 12873 1458 0.34 0.256666667 -0.405638801 Down 0.159182369 Cpa3 "carboxypeptidase A3, mast cell" K08780|1|0.0|858|mmu:12873|carboxypeptidase A3 [EC:3.4.17.1] - - - - 74843 1829 0.243333333 0.323333333 0.410088283 Up 0.159182369 Mss51 MSS51 mitochondrial translational activator K17656|1|0.0|852|mmu:74843|mitochondrial splicing suppressor protein 51 - GO:0046914//transition metal ion binding GO:0051705 gi|111054907|gb|AAI19817.1|/0/Zmynd17 protein [Mus musculus] 108912 3568 0.313333333 0.236666667 -0.404841732 Down 0.159182369 Cdca2 cell division cycle associated 2 K17590|1|0.0|1873|mmu:108912|cell division cycle-associated protein 2 - - - - 434325 1539 0.13 0.2 0.621488377 Up 0.159182369 Tmem221 transmembrane protein 221 - - - - gi|198278541|ref|NP_001093932.1|/1.66741e-55/transmembrane protein 221 [Mus musculus] 16774 10343 0.33 0.25 -0.40053793 Down 0.159182369 Lama3 "laminin, alpha 3" "K06240|1|0.0|6781|mmu:16774|laminin, alpha 3/5" - - - gi|226423935|ref|NP_034810.1|/0/laminin subunit alpha-3 precursor [Mus musculus] 76969 2682 2.306666667 2.14 -0.108198741 Down 0.159172966 Chst1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 K01022|1|0.0|813|mmu:76969|keratan sulfate 6-sulfotransferase 1 [EC:2.8.2.21] GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008146//sulfotransferase activity GO:0006790//sulfur compound metabolic process;GO:0006952//defense response;GO:0019318//hexose metabolic process gi|12963845|ref|NP_076339.1|/0/carbohydrate sulfotransferase 1 precursor [Mus musculus] 245049 4762 2.293333333 2.126666667 -0.108852141 Down 0.159172966 Myrip myosin VIIA and Rab interacting protein K17598|1|4e-14|84.0|pss:102448696|synaptotagmin-like protein GO:0030141//secretory granule;GO:0005856//cytoskeleton;GO:0044459;GO:0048770;GO:0031513//nonmotile primary cilium GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding;GO:0017016//Ras GTPase binding GO:0050796//regulation of insulin secretion;GO:0015031//protein transport "gi|148677228|gb|EDL09175.1|/0/myosin VIIA and Rab interacting protein, partial [Mus musculus]" 67005 2925 2.42 2.25 -0.105082046 Down 0.159172966 Polr3k polymerase (RNA) III (DNA directed) polypeptide K K03019|1|8e-63|244|shr:100917831|DNA-directed RNA polymerase III subunit RPC11 GO:0044451 GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0034062//RNA polymerase activity GO:0006952//defense response;GO:0006383//transcription from RNA polymerase III promoter;GO:0002252 gi|927108841|ref|XP_003124725.3|/6.97791e-62/PREDICTED: DNA-directed RNA polymerase III subunit RPC10 [Sus scrofa] 226144 3202.6 2.256666667 2.09 -0.110690391 Down 0.159172966 Erlin1 ER lipid raft associated 1 - GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex - GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process "gi|148709973|gb|EDL41919.1|/3.52839e-171/SPFH domain family, member 1, isoform CRA_b, partial [Mus musculus]" 217732 4121.6 16.56666667 16.03 -0.047508926 Down 0.159172966 Cipc "CLOCK interacting protein, circadian" - - - - gi|677286759|sp|Q8R0W1.4|CIPC_MOUSE/0/RecName: Full=CLOCK-interacting pacemaker; AltName: Full=CLOCK-interacting circadian protein 338371 5112 2.38 2.21 -0.106915204 Down 0.159172966 Endov endonuclease V "K03849|1|1e-17|95.9|cel:CELE_C08H9.3|alpha-1,3-glucosyltransferase [EC:2.4.1.265];K10591|3|1e-05|56.2|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]" - GO:0043169//cation binding;GO:0004520//endodeoxyribonuclease activity;GO:0043169//cation binding;GO:0004520//endodeoxyribonuclease activity GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress gi|257467544|ref|NP_001158108.1|/0/endonuclease V isoform 1 [Mus musculus] 55936 5602.99 1.473333333 1.336666667 -0.140444133 Down 0.15903193 Ctps2 cytidine 5'-triphosphate synthase 2 K01937|1|0.0|1083|mmu:55936|CTP synthase [EC:6.3.4.2] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0032550;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0032550;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0032550;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0032550;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0032550;GO:0016879//ligase activity, forming carbon-nitrogen bonds" GO:0009064//glutamine family amino acid metabolic process;GO:0006241//CTP biosynthetic process;GO:0009064//glutamine family amino acid metabolic process;GO:0006241//CTP biosynthetic process;GO:0009064//glutamine family amino acid metabolic process;GO:0006241//CTP biosynthetic process;GO:0009064//glutamine family amino acid metabolic process;GO:0006241//CTP biosynthetic process;GO:0009064//glutamine family amino acid metabolic process;GO:0006241//CTP biosynthetic process gi|569012118|ref|XP_006528974.1|/0/PREDICTED: CTP synthase 2 isoform X2 [Mus musculus] 654318 2436 1.396666667 1.536666667 0.137816507 Up 0.15903193 C530005A16Rik RIKEN cDNA C530005A16 gene - - - - - 207785 4126 1.436666667 1.58 0.13719919 Up 0.15903193 Csrnp2 cysteine-serine-rich nuclear protein 2 K17494|1|0.0|872|mmu:207785|cysteine/serine-rich nuclear protein GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0019899//enzyme binding GO:0012501//programmed cell death;GO:0006366//transcription from RNA polymerase II promoter;GO:0010921//regulation of phosphatase activity gi|23510287|ref|NP_700456.1|/0/cysteine/serine-rich nuclear protein 2 [Mus musculus] 68808 777 1.42 1.563333333 0.138734492 Up 0.15903193 1110046J04Rik RIKEN cDNA 1110046J04 gene K10591|1|5e-07|57.0|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26];K09228|2|4e-06|53.9|rno:102551340|KRAB domain-containing zinc finger protein - - - - 83946 10729 1.083333333 1.213333333 0.163498732 Up 0.159022528 Phip pleckstrin homology domain interacting protein K11797|1|0.0|3335|mmu:83946|PH-interacting protein GO:0043231//intracellular membrane-bounded organelle GO:0042393//histone binding;GO:0005102//receptor binding GO:0001934//positive regulation of protein phosphorylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0000902//cell morphogenesis;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007067//mitotic nuclear division;GO:0009967//positive regulation of signal transduction gi|124487035|ref|NP_001074685.1|/0/PH-interacting protein [Mus musculus] 57265 3628 1.143333333 1.276666667 0.159135816 Up 0.159022528 Fzd2 frizzled class receptor 2 K02235|1|0.0|1089|mmu:57265|frizzled 2 - - - - 22388 2878 61.03333333 59.26333333 -0.042457611 Down 0.159022528 Wdr1 WD repeat domain 1 K16482|1|5e-18|96.3|dme:Dmel_CG10191|centriolar protein POC1 GO:0043232 - - "gi|29144967|gb|AAH49117.1|/0/WD repeat domain 1, partial [Mus musculus]" 58220 3409 1.183333333 1.056666667 -0.163336184 Down 0.159022528 Pard6b par-6 family cell polarity regulator beta K06093|1|0.0|642|mmu:58220|partitioning defective protein 6 GO:0043296//apical junction complex;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0005488//binding GO:0016477//cell migration;GO:0007043//cell-cell junction assembly;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0065003 gi|253314520|ref|NP_067384.2|/0/partitioning defective 6 homolog beta [Mus musculus] 20378 2920 1.153333333 1.286666667 0.15782881 Up 0.159022528 Frzb frizzled-related protein K02185|1|7e-91|338|cjo:107309421|secreted frizzled-related protein 4 - - - gi|6755476|ref|NP_035486.1|/0/secreted frizzled-related protein 3 precursor [Mus musculus] 218441 5451 1.213333333 1.086666667 -0.159066486 Down 0.159022528 Zfyve16 "zinc finger, FYVE domain containing 16" "K04679|1|0.0|2753|mmu:218441|MAD, mothers against decapentaplegic interacting protein" GO:0005769//early endosome GO:0043169//cation binding;GO:0043168//anion binding;GO:0022892//substrate-specific transporter activity;GO:0035091//phosphatidylinositol binding GO:0006996//organelle organization;GO:0006623//protein targeting to vacuole;GO:0006897//endocytosis;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway gi|28972139|dbj|BAC65523.1|/0/mKIAA0305 protein [Mus musculus] 15904 1660 0.126666667 0.193333333 0.610053482 Up 0.159003723 Id4 inhibitor of DNA binding 4 K17695|1|2e-60|236|mmu:15904|DNA-binding protein inhibitor ID4 GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0014003//oligodendrocyte development;GO:0045686//negative regulation of glial cell differentiation;GO:0008283//cell proliferation;GO:0045444//fat cell differentiation;GO:0021543//pallium development;GO:0021953//central nervous system neuron differentiation;GO:0008104//protein localization gi|532023738|ref|XP_005355208.1|/1.61705e-59/PREDICTED: DNA-binding protein inhibitor ID-4 [Microtus ochrogaster] 240023 1689 0.143333333 0.216666667 0.596103058 Up 0.159003723 Pnldc1 poly(A)-specific ribonuclease (PARN)-like domain containing 1 K01148|1|6e-44|181|xla:394409|poly(A)-specific ribonuclease [EC:3.1.13.4] - - - gi|198278452|ref|NP_001030038.1|/0/poly(A)-specific ribonuclease PARN-like domain-containing protein 1 [Mus musculus] 239463 2089 0.56 0.663333333 0.244307198 Up 0.158928504 Fam83a "family with sequence similarity 83, member A" K16805|1|2e-39|166|ggo:101129684|protein FAM83D - - - gi|169646258|ref|NP_776287.2|/0/protein FAM83A [Mus musculus] 100972 1234.19 56.58333333 58.28 0.042623709 Up 0.158787469 Rab28 "RAB28, member RAS oncogene family" K07915|1|7e-90|211|mmu:100972|Ras-related protein Rab-28 GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0032550;GO:0032550;GO:0032550 GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process gi|58037191|ref|NP_081571.1|/3.19298e-107/ras-related protein Rab-28 isoform 1 [Mus musculus] 100038714 1464 1.053333333 0.93 -0.179659436 Down 0.158778066 Gm15401 predicted gene 15401 - - - - gi|74203301|dbj|BAE20826.1|/1.29067e-55/unnamed protein product [Mus musculus] 66725 8231 1.006666667 0.886666667 -0.183122304 Down 0.158778066 Lrrk2 leucine-rich repeat kinase 2 K08844|1|0.0|4778|mmu:66725|leucine-rich repeat kinase 2 [EC:2.7.11.1] - - - gi|146231954|ref|NP_080006.3|/0/leucine-rich repeat serine/threonine-protein kinase 2 [Mus musculus] 21750 2619.35 9.686666667 9.323333333 -0.055154449 Down 0.158778066 Terf2 telomeric repeat binding factor 2 K11111|1|0.0|752|mmu:21750|telomeric repeat-binding factor 2 GO:0031981//nuclear lumen;GO:0000782//telomere cap complex;GO:0043234//protein complex GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0003690//double-stranded DNA binding GO:0001304;GO:0034502//protein localization to chromosome;GO:0016233//telomere capping;GO:0006278//RNA-dependent DNA biosynthetic process;GO:0032201//telomere maintenance via semi-conservative replication gi|133904140|ref|NP_001076587.1|/0/telomeric repeat-binding factor 2 isoform 2 [Mus musculus] 19647 4995.74 7.813333333 8.17 0.064397914 Up 0.158778066 Rbbp6 retinoblastoma binding protein 6 K10624|1|9e-51|204|cge:100773570|E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27] GO:0015630//microtubule cytoskeleton;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0019787//ubiquitin-like protein transferase activity GO:0016567//protein ubiquitination "gi|148685341|gb|EDL17288.1|/0/retinoblastoma binding protein 6, isoform CRA_f [Mus musculus]" 15185 4115.27 5.886666667 5.606666667 -0.070307637 Down 0.158721652 Hdac6 histone deacetylase 6 K11407|1|0.0|2247|mmu:15185|histone deacetylase 6 [EC:3.5.1.98] GO:0031981//nuclear lumen;GO:0044459;GO:0005875//microtubule associated complex;GO:0005874//microtubule;GO:0016234//inclusion body;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044459;GO:0005875//microtubule associated complex;GO:0005874//microtubule;GO:0016234//inclusion body;GO:0044444//cytoplasmic part GO:0043130//ubiquitin binding;GO:0032403//protein complex binding;GO:0015631//tubulin binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0046914//transition metal ion binding;GO:0019899//enzyme binding;GO:0031072//heat shock protein binding;GO:0043130//ubiquitin binding;GO:0032403//protein complex binding;GO:0015631//tubulin binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0046914//transition metal ion binding;GO:0019899//enzyme binding;GO:0031072//heat shock protein binding "GO:0034614//cellular response to reactive oxygen species;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0009966//regulation of signal transduction;GO:0032880//regulation of protein localization;GO:0016567//protein ubiquitination;GO:0070841;GO:0006351//transcription, DNA-templated;GO:0016575//histone deacetylation;GO:0031334//positive regulation of protein complex assembly;GO:0010631//epithelial cell migration;GO:0070843//misfolded protein transport;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0035967//cellular response to topologically incorrect protein;GO:0051640//organelle localization;GO:0007019//microtubule depolymerization;GO:0034614//cellular response to reactive oxygen species;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0009966//regulation of signal transduction;GO:0032880//regulation of protein localization;GO:0016567//protein ubiquitination;GO:0070841;GO:0006351//transcription, DNA-templated;GO:0016575//histone deacetylation;GO:0031334//positive regulation of protein complex assembly;GO:0010631//epithelial cell migration;GO:0070843//misfolded protein transport;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0035967//cellular response to topologically incorrect protein;GO:0051640//organelle localization;GO:0007019//microtubule depolymerization" gi|194353997|ref|NP_034543.3|/0/histone deacetylase 6 [Mus musculus] 326618 2082 55.96333333 54.29 -0.043795412 Down 0.158721652 Tpm4 tropomyosin 4 K10375|1|3e-96|355|mmu:326618|tropomyosin 4 GO:0032432//actin filament bundle;GO:0005884//actin filament;GO:0005865//striated muscle thin filament GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0005198//structural molecule activity GO:0044763;GO:0006936//muscle contraction;GO:0006950//response to stress gi|47894398|ref|NP_001001491.1|/2.44762e-95/tropomyosin alpha-4 chain [Mus musculus] 268933 3099 5.963333333 5.686666667 -0.068535741 Down 0.158721652 Wdr24 WD repeat domain 24 K20408|1|0.0|1600|mmu:268933|WD repeat-containing protein 24 GO:0042579//microbody GO:0000268//peroxisome targeting sequence binding GO:0006625//protein targeting to peroxisome gi|30424575|ref|NP_776102.1|/0/WD repeat-containing protein 24 [Mus musculus] 11477 2897.65 6.286666667 6.006666667 -0.065730665 Down 0.158721652 Acvr1 "activin A receptor, type 1" K04675|1|0.0|1022|mmu:11477|activin receptor type-1 [EC:2.7.11.30] - - - - 240672 1155 4.076666667 4.303333333 0.078064597 Up 0.15863703 Dusp5 dual specificity phosphatase 5 K04459|1|0.0|751|mmu:240672|dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] - - - gi|145966803|ref|NP_001078859.1|/0/dual specificity protein phosphatase 5 [Mus musculus] 15463 7858.82 4.496666667 4.266666667 -0.075746538 Down 0.15863703 Agfg1 ArfGAP with FG repeats 1 K15044|1|0.0|799|mmu:15463|Arf-GAP domain and FG repeats-containing protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0044297//cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body GO:0046872//metal ion binding;GO:0005488//binding GO:0003006//developmental process involved in reproduction;GO:0045104//intermediate filament cytoskeleton organization;GO:0048869//cellular developmental process;GO:0006997//nucleus organization;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0045104//intermediate filament cytoskeleton organization;GO:0048869//cellular developmental process;GO:0006997//nucleus organization;GO:0048232//male gamete generation gi|894216216|ref|NP_001297642.1|/0/arf-GAP domain and FG repeat-containing protein 1 isoform 2 [Mus musculus] 67187 2713 4.286666667 4.516666667 0.075402209 Up 0.15863703 Zmynd19 "zinc finger, MYND domain containing 19" K17868|1|8e-20|102|tgu:100220501|diphthine methyl ester acylhydrolase [EC:3.1.1.97] GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - gi|795160986|ref|XP_011840572.1|/2.35499e-112/PREDICTED: zinc finger MYND domain-containing protein 19 [Mandrillus leucophaeus] 268395 1745 4.25 4.023333333 -0.079071571 Down 0.15863703 Mpg N-methylpurine-DNA glycosylase K03652|1|6e-169|596|mmu:268395|DNA-3-methyladenine glycosylase [EC:3.2.2.21] GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0043733//DNA-3-methylbase glycosylase activity GO:0006281//DNA repair gi|500755|gb|AAA19487.1|/5.02542e-168/methyl purine glycosylase [Mus musculus] 75296 3111 4.186666667 3.96 -0.080301628 Down 0.15863703 Fgfr1op Fgfr1 oncogene partner K16546|1|3e-162|575|mmu:75296|FGFR1 oncogene partner GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part GO:0004860//protein kinase inhibitor activity;GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0004860//protein kinase inhibitor activity;GO:0019900//kinase binding;GO:0042802//identical protein binding GO:0016477//cell migration;GO:0016049//cell growth;GO:0000226//microtubule cytoskeleton organization;GO:0006469//negative regulation of protein kinase activity;GO:0008283//cell proliferation;GO:0016477//cell migration;GO:0016049//cell growth;GO:0000226//microtubule cytoskeleton organization;GO:0006469//negative regulation of protein kinase activity;GO:0008283//cell proliferation gi|47777353|ref|NP_957682.1|/6.13264e-165/FGFR1 oncogene partner isoform 2 [Mus musculus] 67873 2149 3.966666667 4.193333333 0.080170349 Up 0.15863703 Mri1 methylthioribose-1-phosphate isomerase 1 K08963|1|3e-178|627|mmu:67873|methylthioribose-1-phosphate isomerase [EC:5.3.1.23] - - - gi|268838020|ref|NP_080699.3|/2.64631e-177/methylthioribose-1-phosphate isomerase [Mus musculus] 171095 2330.71 4.433333333 4.206666667 -0.075714335 Down 0.15863703 Il17rc interleukin 17 receptor C K05166|1|0.0|1391|mmu:171095|interleukin 17 receptor C GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004896//cytokine receptor activity;GO:0004896//cytokine receptor activity GO:0001819//positive regulation of cytokine production;GO:0001819//positive regulation of cytokine production gi|282399145|ref|NP_598920.3|/0/interleukin-17 receptor C isoform 2 precursor [Mus musculus] 434689 2984 0.386666667 0.473333333 0.291766124 Up 0.158514799 Gm10220 predicted gene 10220 - - - - "gi|148668757|gb|EDL01004.1|/7.25191e-123/mCG129471, partial [Mus musculus]" 68145 4192 0.393333333 0.48 0.287281952 Up 0.158514799 Etaa1 Ewing tumor-associated antigen 1 - GO:0031981//nuclear lumen - - gi|257153368|ref|NP_080852.2|/0/ewing's tumor-associated antigen 1 homolog [Mus musculus] 432488 855 0.413333333 0.506666667 0.293731203 Up 0.158514799 Gm17745 "predicted gene, 17745" - - - - - 26559 5009 0.276666667 0.36 0.379848071 Up 0.158505397 Hunk hormonally upregulated Neu-associated kinase K08797|1|0.0|1317|mmu:26559|hormonally upregulated Neu-associated kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032550 GO:0032502//developmental process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007154//cell communication gi|7657216|ref|NP_056570.1|/0/hormonally up-regulated neu tumor-associated kinase [Mus musculus] 19719 2141 16.47333333 16.99666667 0.045119327 Up 0.158401971 Rfng RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase K05948|1|3e-169|597|mmu:19719|fringe [EC:2.4.1.222] GO:0031228//intrinsic component of Golgi membrane GO:0043169//cation binding;GO:0008375//acetylglucosaminyltransferase activity GO:0048869//cellular developmental process;GO:0048731//system development;GO:0043393//regulation of protein binding;GO:0007219//Notch signaling pathway "gi|6677725|ref|NP_033079.1|/2.91709e-168/beta-1,3-N-acetylglucosaminyltransferase radical fringe [Mus musculus]" 20443 2059 14.29333333 13.77 -0.053813846 Down 0.158401971 St3gal4 "ST3 beta-galactoside alpha-2,3-sialyltransferase 4" "K03494|1|0.0|648|mmu:20443|beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4C) [EC:2.4.99.4]" GO:0031228//intrinsic component of Golgi membrane GO:0008373//sialyltransferase activity GO:0006464//cellular protein modification process "gi|755528480|ref|XP_011240734.1|/0/PREDICTED: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform X10 [Mus musculus]" 50797 3043 53.94666667 52.37666667 -0.042609572 Down 0.158307947 Copb2 "coatomer protein complex, subunit beta 2 (beta prime)" K17302|1|0.0|1774|mmu:50797|coatomer subunit beta' GO:0005856//cytoskeleton;GO:0030137//COPI-coated vesicle;GO:0030120//vesicle coat GO:0019901//protein kinase binding GO:0048193//Golgi vesicle transport;GO:0015031//protein transport gi|29789080|ref|NP_056642.1|/0/coatomer subunit beta' [Mus musculus] 65113 1012 61.01666667 62.58 0.036498291 Up 0.158251533 Ndfip1 Nedd4 family interacting protein 1 - GO:0031228//intrinsic component of Golgi membrane GO:0060089;GO:0019904//protein domain specific binding GO:0006954//inflammatory response;GO:0010467//gene expression;GO:0032409;GO:0030098//lymphocyte differentiation;GO:0016567//protein ubiquitination;GO:0015031//protein transport;GO:0045829;GO:0009896;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002573//myeloid leukocyte differentiation;GO:0002828//regulation of type 2 immune response;GO:0042098//T cell proliferation;GO:0001818//negative regulation of cytokine production;GO:0006875//cellular metal ion homeostasis;GO:0006511//ubiquitin-dependent protein catabolic process gi|12004976|gb|AAG44248.1|/1.23962e-113/Nedd4 WW domain-binding protein 5 [Mus musculus] 69572 2169 2.56 2.74 0.098032083 Up 0.15824213 Mfsd3 major facilitator superfamily domain containing 3 K10730|1|4e-34|92.4|mmu:79456|ATP-dependent DNA helicase Q4 [EC:3.6.4.12] - - - gi|81889681|sp|Q5U419.1|MFSD3_MOUSE/9.5783e-151/RecName: Full=Major facilitator superfamily domain-containing protein 3 50758 17001 2.533333333 2.71 0.097255934 Up 0.15824213 Fbxl17 F-box and leucine-rich repeat protein 17 K10283|1|0.0|1050|mmu:50758|F-box and leucine-rich repeat protein 17 - - - gi|255683359|ref|NP_056609.1|/0/F-box/LRR-repeat protein 17 [Mus musculus] 67139 2766 2.483333333 2.663333333 0.100955078 Up 0.15824213 Mis12 MIS12 kinetochore complex component K11543|1|1e-94|350|mmu:67139|kinetochore-associated protein MIS12 "GO:0043231//intracellular membrane-bounded organelle;GO:0000775//chromosome, centromeric region" - GO:0034508//centromere complex assembly;GO:0000087//mitotic M phase gi|21313120|ref|NP_080269.1|/1.10332e-93/protein MIS12 homolog [Mus musculus] 215929 2679 2.58 2.763333333 0.099038535 Up 0.15824213 Mfsd4b1 major facilitator superfamily domain containing 4B1 "K08175|1|0.0|783|mmu:215929|MFS transporter, FHS family, Na+ dependent glucose transporter 1" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0030001//metal ion transport;GO:0044763 gi|295444876|ref|NP_659070.2|/0/sodium-dependent glucose transporter 1A [Mus musculus] 109299 2460.16 53.64666667 55.19666667 0.041092613 Up 0.158232728 C330006A16Rik RIKEN cDNA C330006A16 gene K13720|1|3e-37|159|tup:102471067|N-acylethanolamine-hydrolysing acid amidase [EC:3.5.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0032550;GO:0032550 GO:0044763;GO:0008283//cell proliferation;GO:0044763;GO:0008283//cell proliferation gi|441623341|ref|XP_004088903.1|/2.38302e-53/PREDICTED: protein C9orf69 homolog isoform X1 [Nomascus leucogenys] 83409 586 54.19666667 55.70333333 0.03955954 Up 0.158091692 Lamtor2 "late endosomal/lysosomal adaptor, MAPK and MTOR activator 2" K20398|1|8e-64|244|rno:295234|ragulator complex protein LAMTOR2 GO:0005764//lysosome;GO:0031902//late endosome membrane GO:0030695//GTPase regulator activity;GO:0005515//protein binding GO:0040007//growth;GO:0006468//protein phosphorylation;GO:0009967//positive regulation of signal transduction;GO:0008104//protein localization;GO:0043200//response to amino acid "gi|62738001|pdb|1SZV|A/5.4284e-63/Chain A, Structure Of The Adaptor Protein P14 Reveals A Profilin- Like Fold With Novel Function" 74237 3016.53 13.99 14.5 0.051656938 Up 0.158072887 Tubgcp2 "tubulin, gamma complex associated protein 2" K16569|1|0.0|1371|mmu:74237|gamma-tubulin complex component 2 GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0031981//nuclear lumen;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0031981//nuclear lumen;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0031981//nuclear lumen;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0031981//nuclear lumen "GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway "gi|148685935|gb|EDL17882.1|/0/tubulin, gamma complex associated protein 2, isoform CRA_c, partial [Mus musculus]" 227801 4352 13.77 14.28 0.05246742 Up 0.158072887 Dennd1a DENN/MADD domain containing 1A K20160|1|0.0|1705|mmu:227801|DENN domain-containing protein 1 GO:0043005//neuron projection;GO:0044297//cell body;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0019904//protein domain specific binding GO:0019222//regulation of metabolic process;GO:0045184//establishment of protein localization;GO:0006897//endocytosis gi|254675212|ref|NP_666234.3|/0/DENN domain-containing protein 1A [Mus musculus] 14300 1106 14.15 13.64 -0.052958409 Down 0.158072887 Frg1 FSHD region gene 1 K13122|1|6e-133|476|mmu:14300|protein FRG1 GO:0005681//spliceosomal complex - GO:0042254//ribosome biogenesis;GO:0006396//RNA processing gi|225543552|ref|NP_038550.2|/5.21396e-132/protein FRG1 [Mus musculus] 23943 3687 15.66333333 15.15666667 -0.047438764 Down 0.158072887 Esyt1 extended synaptotagmin-like protein 1 K19513|1|7e-25|119|tsp:Tsp_01622|protein CLEC16A;K00923|3|2e-15|87.8|mdo:100017523|phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154] GO:0031224//intrinsic component of membrane - - gi|33859650|ref|NP_035973.1|/0/extended synaptotagmin-1 [Mus musculus] 213436 3019 0.353333333 0.273333333 -0.37036845 Down 0.158063485 Zcchc5 "zinc finger, CCHC domain containing 5" "K10798|1|5e-23|83.6|dre:558045|poly [ADP-ribose] polymerase [EC:2.4.2.30];K18438|3|5e-08|63.2|gja:107119131|cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35];K06237|4|4e-07|60.1|ola:101166113|collagen, type IV, alpha" - GO:0043169//cation binding - gi|41054992|ref|NP_955762.1|/0/zinc finger CCHC domain-containing protein 5 [Mus musculus] 30934 2997 8.316666667 8.666666667 0.059471808 Up 0.157960059 Tor1b "torsin family 1, member B" "K01056|1|1e-25|121|tgu:100227249|peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29];K03695|2|2e-07|60.8|mze:101482743|ATP-dependent Clp protease ATP-binding subunit ClpB" GO:0044432;GO:0012505//endomembrane system GO:0032550;GO:0005515//protein binding;GO:0016462//pyrophosphatase activity GO:0051084//'de novo' posttranslational protein folding;GO:0006998//nuclear envelope organization;GO:0051259//protein oligomerization;GO:0035966//response to topologically incorrect protein gi|31559990|ref|NP_598434.2|/0/torsin-1B precursor [Mus musculus] 74123 4037.26 8.916666667 9.27 0.056064853 Up 0.157960059 Foxp4 forkhead box P4 K09409|1|0.0|825|mmu:74123|forkhead box protein P - - - gi|161016782|ref|NP_001104294.1|/0/forkhead box protein P4 isoform 1 [Mus musculus] 19414 4118 8.203333333 8.55 0.059714168 Up 0.157960059 Rasa3 RAS p21 protein activator 3 K12380|1|0.0|1657|mmu:19414|Ras GTPase-activating protein 3 - - - gi|120444918|ref|NP_033051.2|/0/ras GTPase-activating protein 3 [Mus musculus] 98267 3298 3.243333333 3.04 -0.093405981 Down 0.157809621 Stk17b serine/threonine kinase 17b (apoptosis-inducing) K08804|1|0.0|749|mmu:98267|serine/threonine kinase 17 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0016020//membrane GO:0032550;GO:0004672//protein kinase activity GO:0012502//induction of programmed cell death;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction "gi|148667586|gb|EDL00003.1|/0/serine/threonine kinase 17b (apoptosis-inducing), isoform CRA_b, partial [Mus musculus]" 53951 4237 3.256666667 3.06 -0.089864409 Down 0.157809621 Gpatch11 G patch domain containing 11 K13094|1|1e-07|62.4|hro:HELRODRAFT_87741|RNA-binding protein 5/10 - GO:0097159//organic cyclic compound binding - gi|194473718|ref|NP_857632.4|/1.49471e-132/G patch domain-containing protein 11 [Mus musculus] 66658 2397 3.136666667 3.333333333 0.087733372 Up 0.157809621 Ccdc51 coiled-coil domain containing 51 - GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen - - gi|258679490|ref|NP_079965.2|/0/coiled-coil domain-containing protein 51 [Mus musculus] 67144 2693.38 3.116666667 3.32 0.091179377 Up 0.157809621 Lrrc40 leucine rich repeat containing 40 K19613|1|2e-41|174|bfo:BRAFLDRAFT_214464|leucine-rich repeat protein SHOC2 - - - gi|31541911|ref|NP_077156.2|/0/leucine-rich repeat-containing protein 40 isoform a [Mus musculus] 30926 1651 53.25333333 51.79333333 -0.040105421 Down 0.157772011 Glrx3 glutaredoxin 3 K15216|1|5e-37|158|tsp:Tsp_09255|RNA polymerase I-specific transcription initiation factor RRN3;K07390|3|6e-22|108|loa:LOAG_09509|monothiol glutaredoxin GO:0031674//I band GO:0043169//cation binding;GO:0051540;GO:0019901//protein kinase binding;GO:0015036//disulfide oxidoreductase activity GO:0003300//cardiac muscle hypertrophy;GO:0008016//regulation of heart contraction;GO:0044710;GO:0019725//cellular homeostasis gi|31981269|ref|NP_075629.2|/0/glutaredoxin-3 [Mus musculus] 194974 1101 0.376666667 0.293333333 -0.360747344 Down 0.157753206 Sun3 Sad1 and UNC84 domain containing 3 K19347|1|1e-51|206|fch:102055344|SUN domain-containing protein 1/2 GO:0034992//microtubule organizing center attachment site;GO:0031224//intrinsic component of membrane;GO:0034992//microtubule organizing center attachment site;GO:0031224//intrinsic component of membrane;GO:0034992//microtubule organizing center attachment site;GO:0031224//intrinsic component of membrane - - gi|564317332|ref|XP_006221904.1|/1.7425e-178/PREDICTED: SUN domain-containing protein 3 isoform X1 [Rattus norvegicus] 74243 2293.94 0.35 0.273333333 -0.356693513 Down 0.157753206 Slx4ip SLX4 interacting protein - - - - gi|21312668|ref|NP_083110.1|/0/protein SLX4IP isoform 1 [Mus musculus] 67217 1705 5.1 5.37 0.074424841 Up 0.157743804 L3hypdh L-3-hydroxyproline dehydratase (trans-) K18384|1|0.0|709|mmu:67217|trans-L-3-hydroxyproline dehydratase [EC:4.2.1.77] - GO:0047661//amino-acid racemase activity;GO:0016836//hydro-lyase activity - "gi|148704596|gb|EDL36543.1|/0/RIKEN cDNA 2810055F11, partial [Mus musculus]" 104263 4830 6.18 5.906666667 -0.06526264 Down 0.157743804 Kdm3a lysine (K)-specific demethylase 3A K15601|1|0.0|2693|mmu:104263|lysine-specific demethylase 3 [EC:1.14.11.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0016741;GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0035258//steroid hormone receptor binding;GO:0046914//transition metal ion binding;GO:0016741;GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0035258//steroid hormone receptor binding" GO:0070076//histone lysine demethylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0044283//small molecule biosynthetic process;GO:0018027//peptidyl-lysine dimethylation;GO:0048869//cellular developmental process;GO:0006997//nucleus organization;GO:0048232//male gamete generation;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0031061//negative regulation of histone methylation;GO:0070076//histone lysine demethylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0044283//small molecule biosynthetic process;GO:0018027//peptidyl-lysine dimethylation;GO:0048869//cellular developmental process;GO:0006997//nucleus organization;GO:0048232//male gamete generation;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0031061//negative regulation of histone methylation gi|37360072|dbj|BAC98014.1|/0/mKIAA0742 protein [Mus musculus] 72843 3954.99 5.296666667 5.03 -0.074526319 Down 0.157743804 Prdm4 PR domain containing 4 K12463|1|0.0|1415|mmu:72843|PR domain zinc finger protein 4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0032813//tumor necrosis factor receptor superfamily binding "GO:0016049//cell growth;GO:0006351//transcription, DNA-templated;GO:0016049//cell growth;GO:0006351//transcription, DNA-templated;GO:0016049//cell growth;GO:0007584//response to nutrient;GO:0070848//response to growth factor;GO:0006351//transcription, DNA-templated" "gi|148689477|gb|EDL21424.1|/0/PR domain containing 4, isoform CRA_b, partial [Mus musculus]" 19128 3314 5.26 5.526666667 0.071346801 Up 0.157743804 Pros1 protein S (alpha) K03908|1|0.0|1392|mmu:19128|protein S - - - - 78885 3518 5.503333333 5.773333333 0.06909881 Up 0.157743804 Coro7 coronin 7 K18619|1|0.0|1694|mmu:78885|coronin-7 - - - gi|148747331|ref|NP_084481.3|/0/coronin-7 [Mus musculus] 227738 4002 5.406666667 5.68 0.071151516 Up 0.157743804 Lrsam1 leucine rich repeat and sterile alpha motif containing 1 K10641|1|0.0|1233|mmu:227738|E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27] - - - - 664883 7000 0.496666667 0.41 -0.276654015 Down 0.157715597 Nova1 neuro-oncological ventral antigen 1 K14944|1|4e-145|519|mmu:664883|RNA-binding protein Nova GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding GO:0000377;GO:0048731//system development;GO:0044708//single-organism behavior;GO:0007267//cell-cell signaling gi|488534205|ref|XP_004458817.1|/2.86916e-144/PREDICTED: RNA-binding protein Nova-1 [Dasypus novemcinctus] 18796 5091 0.406666667 0.493333333 0.278716028 Up 0.157715597 Plcb2 "phospholipase C, beta 2" "K05858|1|0.0|2131|mmu:18796|phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]" GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0004629//phospholipase C activity;GO:0046872//metal ion binding;GO:0060089;GO:0032403//protein complex binding;GO:0008289//lipid binding GO:0006644//phospholipid metabolic process;GO:0050912//detection of chemical stimulus involved in sensory perception of taste;GO:0007165//signal transduction "gi|61676179|ref|NP_808236.2|/0/1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform a [Mus musculus]" 76707 7659.33 51.68666667 50.26333333 -0.040285814 Down 0.157621573 Clasp1 CLIP associating protein 1 K16578|1|0.0|2348|rno:304740|CLIP-associating protein 1/2 - - - gi|648215678|ref|NP_001280230.1|/0/CLIP-associating protein 1 isoform 5 [Mus musculus] 74782 2153 0.733333333 0.843333333 0.201633861 Up 0.157602768 Glt8d2 glycosyltransferase 8 domain containing 2 - GO:0031224//intrinsic component of membrane GO:0016740//transferase activity - gi|251823806|ref|NP_083378.2|/0/glycosyltransferase 8 domain-containing protein 2 [Mus musculus] 67864 2133 12.98333333 13.48666667 0.054872992 Up 0.157602768 Yipf4 "Yip1 domain family, member 4" - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|28076889|ref|NP_080693.2|/5.96974e-97/protein YIPF4 [Mus musculus] 381979 3014 0.73 0.836666667 0.196756494 Up 0.157602768 Brsk1 BR serine/threonine kinase 1 K08796|1|0.0|639|lve:103081736|BR serine/threonine kinase [EC:2.7.11.1] GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0030136//clathrin-coated vesicle;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0030136//clathrin-coated vesicle GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0019900//kinase binding;GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0015631//tubulin binding;GO:0019900//kinase binding GO:0007098//centrosome cycle;GO:0007163//establishment or maintenance of cell polarity;GO:0031572//G2 DNA damage checkpoint;GO:0031175//neuron projection development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006468//protein phosphorylation;GO:0009416//response to light stimulus;GO:0001505//regulation of neurotransmitter levels;GO:0007098//centrosome cycle;GO:0007163//establishment or maintenance of cell polarity;GO:0031572//G2 DNA damage checkpoint;GO:0031175//neuron projection development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006468//protein phosphorylation;GO:0009416//response to light stimulus;GO:0001505//regulation of neurotransmitter levels gi|744598741|ref|XP_010989787.1|/0/PREDICTED: serine/threonine-protein kinase BRSK1 [Camelus dromedarius] 269717 3851 0.763333333 0.876666667 0.199715201 Up 0.157602768 Orai2 ORAI calcium release-activated calcium modulator 2 K16057|1|3e-162|575|rno:304592|calcium release-activated calcium channel protein 2 GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane GO:0005488//binding - gi|281371452|ref|NP_001163874.1|/2.35439e-161/protein orai-2 [Rattus norvegicus] 72205 2255 13.49666667 13 -0.054091519 Down 0.157602768 Eml2 echinoderm microtubule associated protein like 2 K18595|1|0.0|1326|mmu:72205|echinoderm microtubule-associated protein-like 1/2 GO:0015630//microtubule cytoskeleton;GO:0043227//membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043227//membrane-bounded organelle GO:0005515//protein binding;GO:0005515//protein binding - gi|244790233|ref|NP_082429.1|/0/echinoderm microtubule-associated protein-like 2 isoform 1 [Mus musculus] 238692 3252 1.18 1.313333333 0.154446269 Up 0.157546354 Zfp874a zinc finger protein 874a K09228|1|0.0|964|mmu:238692|KRAB domain-containing zinc finger protein - - - gi|29244168|ref|NP_808380.1|/0/zinc finger protein 874 [Mus musculus] 435811 1828 1.176666667 1.303333333 0.147500424 Up 0.157546354 Ldlrad2 low density lipoprotein receptor A domain containing 2 K06255|1|2e-06|57.0|ptg:102954270|heparan sulfate proteoglycan 2 (perlecan) - - - gi|568931553|ref|XP_006539076.1|/6.05435e-87/PREDICTED: low-density lipoprotein receptor class A domain-containing protein 2 isoform X1 [Mus musculus] 63857 2382.11 1.353333333 1.22 -0.149636079 Down 0.157546354 Bco1 beta-carotene oxygenase 1 "K00515|1|0.0|1110|mmu:63857|beta-carotene 15,15'-dioxygenase [EC:1.13.11.63]" - - - - 74186 2769 1.373333333 1.24 -0.147341716 Down 0.157546354 Ccdc3 coiled-coil domain containing 3 - - - - "gi|148676017|gb|EDL07964.1|/2.34237e-144/coiled-coil domain containing 3, isoform CRA_b [Mus musculus]" 279028 3447 1.323333333 1.193333333 -0.14917942 Down 0.157546354 Adamts13 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13" K08627|1|0.0|3004|mmu:279028|a disintegrin and metalloproteinase with thrombospondin motifs 13 [EC:3.4.24.87] GO:0044421;GO:0031012//extracellular matrix;GO:0044421;GO:0031012//extracellular matrix;GO:0044421;GO:0044421;GO:0031012//extracellular matrix GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0046872//metal ion binding;GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0007599//hemostasis;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0006518//peptide metabolic process;GO:0007599//hemostasis;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0006518//peptide metabolic process;GO:0007599//hemostasis;GO:0019538//protein metabolic process;GO:0050896//response to stimulus;GO:0006518//peptide metabolic process;GO:0007599//hemostasis;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0006518//peptide metabolic process gi|594191006|ref|NP_001277394.1|/0/A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform IAP-b [Mus musculus] 100504263 4126.07 1.17 1.3 0.152003093 Up 0.157546354 2210418O10Rik predicted gene 2210418O10Rik K09228|1|5e-31|140|mmu:664987|KRAB domain-containing zinc finger protein - - - - 26920 7612 1.073333333 0.953333333 -0.171045541 Down 0.157339501 Cntrl centriolin K16770|1|0.0|3423|rno:311886|centriolin - - - - 20637 2989.48 45.97 44.59 -0.043972467 Down 0.157339501 Snrnp70 small nuclear ribonucleoprotein 70 (U1) K11093|1|2e-69|267|rno:361574|U1 small nuclear ribonucleoprotein 70kDa GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex;GO:0005654//nucleoplasm;GO:0030529//intracellular ribonucleoprotein complex;GO:0005654//nucleoplasm;GO:0030529//intracellular ribonucleoprotein complex GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0000377;GO:0000377;GO:0000377 gi|825725|emb|CAA29964.1|/9.23412e-71/hU1-70K-like protein (216 AA) [Homo sapiens] 226352 6510 0.936666667 1.056666667 0.17391271 Up 0.157339501 Epb41l5 erythrocyte membrane protein band 4.1 like 5 K06107|1|5e-81|306|phi:102114586|erythrocyte membrane protein band 4.1 GO:0001726//ruffle;GO:0005924//cell-substrate adherens junction;GO:0044425;GO:0043232;GO:0001726//ruffle;GO:0005924//cell-substrate adherens junction;GO:0044425;GO:0043232 GO:0005515//protein binding;GO:0005515//protein binding GO:0071363//cellular response to growth factor stimulus;GO:0001840//neural plate development;GO:0010631//epithelial cell migration;GO:0001837//epithelial to mesenchymal transition;GO:0043393//regulation of protein binding;GO:0003382//epithelial cell morphogenesis;GO:0010468//regulation of gene expression;GO:0007440//foregut morphogenesis;GO:0007162//negative regulation of cell adhesion;GO:0006929//substrate-dependent cell migration;GO:0048318//axial mesoderm development;GO:0030036//actin cytoskeleton organization;GO:0032880//regulation of protein localization;GO:0001954//positive regulation of cell-matrix adhesion;GO:0000578//embryonic axis specification;GO:0009952//anterior/posterior pattern specification;GO:0001707//mesoderm formation;GO:0071363//cellular response to growth factor stimulus;GO:0001840//neural plate development;GO:0010631//epithelial cell migration;GO:0001837//epithelial to mesenchymal transition;GO:0043393//regulation of protein binding;GO:0003382//epithelial cell morphogenesis;GO:0010468//regulation of gene expression;GO:0007440//foregut morphogenesis;GO:0007162//negative regulation of cell adhesion;GO:0006929//substrate-dependent cell migration;GO:0048318//axial mesoderm development;GO:0030036//actin cytoskeleton organization;GO:0032880//regulation of protein localization;GO:0001954//positive regulation of cell-matrix adhesion;GO:0000578//embryonic axis specification;GO:0009952//anterior/posterior pattern specification;GO:0001707//mesoderm formation gi|164663872|ref|NP_001106887.1|/0/band 4.1-like protein 5 isoform 2 [Mus musculus] 72899 2830.01 1.11 0.986666667 -0.169925001 Down 0.157339501 Macrod2 MACRO domain containing 2 - - GO:0016787//hydrolase activity;GO:0016787//hydrolase activity GO:0009116//nucleoside metabolic process;GO:0009116//nucleoside metabolic process gi|148227060|ref|NP_001013824.2|/0/O-acetyl-ADP-ribose deacetylase MACROD2 isoform 1 [Mus musculus] 630579 3114 0.143333333 0.21 0.551015169 Up 0.157264282 Zfp808 zinc finger protein 80 K09228|1|0.0|1662|mmu:630579|KRAB domain-containing zinc finger protein - - - gi|110815832|ref|NP_001034328.2|/0/zinc finger protein 80 [Mus musculus] 433882 2516 0.146666667 0.216666667 0.562936194 Up 0.157264282 Gm16223 predicted gene 16223 - - - - - 16561 8452.14 14.46 14.95333333 0.048399567 Up 0.157179661 Kif1b kinesin family member 1B K10392|1|0.0|3175|mmu:16561|kinesin family member 1 GO:0012506//vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0042995//cell projection;GO:0012506//vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0042995//cell projection "GO:0032550;GO:0000166//nucleotide binding;GO:0046983//protein dimerization activity;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0003774//motor activity;GO:0008289//lipid binding;GO:0015631//tubulin binding;GO:0032550;GO:0003774//motor activity;GO:0008289//lipid binding;GO:0015631//tubulin binding" "GO:0007275//multicellular organism development;GO:0006007//glucose catabolic process;GO:0007268//chemical synaptic transmission;GO:0034643//establishment of mitochondrion localization, microtubule-mediated;GO:0009154//purine ribonucleotide catabolic process;GO:0008088//axo-dendritic transport;GO:0007275//multicellular organism development;GO:0012501//programmed cell death;GO:0007268//chemical synaptic transmission;GO:0034643//establishment of mitochondrion localization, microtubule-mediated;GO:0009154//purine ribonucleotide catabolic process;GO:0008088//axo-dendritic transport" gi|86990460|ref|NP_997565.2|/0/kinesin-like protein KIF1B isoform b [Mus musculus] 60365 2629.79 13.13 13.61666667 0.052506661 Up 0.157179661 Rbm8a RNA binding motif protein 8a K12876|1|2e-76|290|bta:518045|RNA-binding protein 8A - - - - 60409 1196 13.86333333 13.37333333 -0.051915079 Down 0.157179661 Trappc4 trafficking protein particle complex 4 K20303|1|2e-121|438|mmu:60409|trafficking protein particle complex subunit 4 GO:0043005//neuron projection;GO:0030136//clathrin-coated vesicle;GO:0097060//synaptic membrane;GO:0005801//cis-Golgi network;GO:0044431//Golgi apparatus part GO:0005488//binding GO:0032800//receptor biosynthetic process;GO:0031175//neuron projection development;GO:0016482//cytosolic transport gi|664709396|ref|XP_008511651.1|/9.39362e-122/PREDICTED: trafficking protein particle complex subunit 4 [Equus przewalskii] 114886 2331 42.76666667 44.11333333 0.044728014 Up 0.157170258 Cygb cytoglobin K13825|1|3e-14|83.2|shr:100919393|hemoglobin subunit epsilon;K13826|2|5e-14|82.4|cmy:102945818|hemoglobin subunit zeta - - - - 56205 1987.89 53.16 51.82333333 -0.03673929 Down 0.157113844 Ensa endosulfine alpha - GO:0044424;GO:0044424 GO:0019888//protein phosphatase regulator activity;GO:0019903//protein phosphatase binding;GO:0019212//phosphatase inhibitor activity;GO:0008200//ion channel inhibitor activity;GO:0019888//protein phosphatase regulator activity;GO:0019903//protein phosphatase binding;GO:0019212//phosphatase inhibitor activity;GO:0008200//ion channel inhibitor activity GO:0009746;GO:0044092//negative regulation of molecular function;GO:0031667//response to nutrient levels;GO:0044772//mitotic cell cycle phase transition;GO:0000087//mitotic M phase;GO:0030073//insulin secretion;GO:0009746;GO:0044092//negative regulation of molecular function;GO:0031667//response to nutrient levels;GO:0044772//mitotic cell cycle phase transition;GO:0000087//mitotic M phase;GO:0030073//insulin secretion gi|9624979|ref|NP_062507.1|/2.86526e-46/alpha-endosulfine isoform a [Mus musculus] 64113 3684 1.633333333 1.78 0.124057993 Up 0.157085637 Moap1 modulator of apoptosis 1 K17561|1|2e-17|94.4|cge:103164277|coiled-coil domain-containing protein 8;K02183|4|2e-11|74.3|umr:103657204|calmodulin GO:0044424;GO:0044424 GO:0042802//identical protein binding;GO:0042802//identical protein binding GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0006921//cellular component disassembly involved in execution phase of apoptosis gi|11612503|ref|NP_071718.1|/0/modulator of apoptosis 1 [Mus musculus] 19268 7648 1.7 1.846666667 0.119388729 Up 0.157085637 Ptprf "protein tyrosine phosphatase, receptor type, F" K05695|1|0.0|3683|mmu:19268|receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48] GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0031224//intrinsic component of membrane;GO:0045202//synapse GO:0005102//receptor binding;GO:0004725//protein tyrosine phosphatase activity;GO:0043168//anion binding;GO:0005539//glycosaminoglycan binding GO:0048731//system development;GO:0008286//insulin receptor signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0008283//cell proliferation;GO:0016337//single organismal cell-cell adhesion;GO:0031346//positive regulation of cell projection organization;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0007268//chemical synaptic transmission;GO:0006470//protein dephosphorylation gi|115648048|ref|NP_035343.2|/0/receptor-type tyrosine-protein phosphatase F precursor [Mus musculus] 20662 8919 1.846666667 2 0.115076524 Up 0.157085637 Sos1 son of sevenless homolog 1 (Drosophila) K03099|1|0.0|2425|mmu:20662|son of sevenless GO:0032991//macromolecular complex;GO:0044297//cell body;GO:0044327//dendritic spine head;GO:0016020//membrane GO:0003676//nucleic acid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding GO:0019222//regulation of metabolic process;GO:0007266//Rho protein signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway "gi|148706579|gb|EDL38526.1|/0/Son of sevenless homolog 1 (Drosophila), partial [Mus musculus]" 66491 1671 49.11333333 50.44 0.038453534 Up 0.15705743 Polr2l polymerase (RNA) II (DNA directed) polypeptide L "K03007|1|2e-30|136|hgl:101723718|DNA-directed RNA polymerases I, II, and III subunit RPABC5" "GO:0016591//DNA-directed RNA polymerase II, holoenzyme" GO:0046914//transition metal ion binding;GO:0016301//kinase activity;GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity GO:0006383//transcription from RNA polymerase III promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006397//mRNA processing;GO:0044764;GO:0006289//nucleotide-excision repair;GO:0000377;GO:0006464//cellular protein modification process;GO:0006360//transcription from RNA polymerase I promoter gi|33086454|gb|AAP92539.1|/1.06588e-34/Ab1-108 [Rattus norvegicus] 19153 4668 0.526666667 0.436666667 -0.270357747 Down 0.157029223 Prx periaxin K12567|1|1e-38|165|ptr:459784|titin [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0005488//binding;GO:0005488//binding GO:0007272//ensheathment of neurons;GO:0007272//ensheathment of neurons gi|170172589|ref|NP_932165.2|/0/periaxin isoform L [Mus musculus] 22746 2218 0.51 0.423333333 -0.268703156 Down 0.157029223 Zfp85 zinc finger protein 85 K09228|1|0.0|1036|mmu:22746|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|47564117|ref|NP_001001130.1|/0/zinc finger protein 85 [Mus musculus] 16516 5250.69 0.436666667 0.526666667 0.270357747 Up 0.157029223 Kcnj15 "potassium inwardly-rectifying channel, subfamily J, member 15" K05008|1|0.0|712|rno:170847|potassium inwardly-rectifying channel subfamily J member 15 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|84872185|ref|NP_001034146.1|/0/ATP-sensitive inward rectifier potassium channel 15 isoform a [Mus musculus] 12817 2972 0.533333333 0.443333333 -0.266645659 Down 0.157029223 Col13a1 "collagen, type XIII, alpha 1" "K16617|1|6e-122|441|mmu:12817|collagen, type XIII, alpha" GO:0030054//cell junction - GO:0007155//cell adhesion;GO:0044699 gi|755571595|ref|NP_001291686.1|/6.09579e-130/collagen alpha-1(XIII) chain isoform 2 [Mus musculus] 73247 1192 7.87 8.213333333 0.061604214 Up 0.157010418 Mrgbp MRG/MORF4L binding protein K11343|1|9e-80|299|rno:311713|MRG-binding protein GO:0000123//histone acetyltransferase complex - "GO:0040007//growth;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" gi|507571907|ref|XP_004669550.1|/9.42836e-82/PREDICTED: MRG/MORF4L-binding protein [Jaculus jaculus] 55942 1188 8.27 7.926666667 -0.06117302 Down 0.157010418 Sertad1 SERTA domain containing 1 - - GO:0005488//binding "GO:0051726//regulation of cell cycle;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation" gi|9055332|ref|NP_061290.1|/6.52935e-83/SERTA domain-containing protein 1 [Mus musculus] 66795 1609 7.983333333 8.323333333 0.060170165 Up 0.157010418 Atg10 autophagy related 10 "K17888|1|6e-114|413|mmu:66795|ubiquitin-like-conjugating enzyme ATG10, animal type" GO:0044424 GO:0019787//ubiquitin-like protein transferase activity GO:0070647//protein modification by small protein conjugation or removal;GO:0045184//establishment of protein localization;GO:0006914//autophagy gi|114158679|ref|NP_080046.3|/5.43517e-113/ubiquitin-like-conjugating enzyme ATG10 [Mus musculus] 67136 2371.61 8.783333333 9.126666667 0.055319485 Up 0.157010418 Kbtbd4 kelch repeat and BTB (POZ) domain containing 4 K10472|1|0.0|1076|cjc:100393087|kelch repeat and BTB domain-containing protein 4 - - - gi|667307810|ref|XP_008583498.1|/0/PREDICTED: kelch repeat and BTB domain-containing protein 4 [Galeopterus variegatus] 68092 2054 8.043333333 7.706666667 -0.061686518 Down 0.157010418 Ncbp2 nuclear cap binding protein subunit 2 K12883|1|1e-79|300|rno:103690107|nuclear cap-binding protein subunit 2 GO:0031981//nuclear lumen;GO:0034518//RNA cap binding complex;GO:0005789//endoplasmic reticulum membrane "GO:0016758//transferase activity, transferring hexosyl groups;GO:0036094//small molecule binding;GO:0000339//RNA cap binding" "GO:0006413//translational initiation;GO:0016458//gene silencing;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006497//protein lipidation;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0044764;GO:0000398//mRNA splicing, via spliceosome;GO:0006405//RNA export from nucleus" gi|672071353|ref|XP_008767006.1|/1.198e-78/PREDICTED: nuclear cap-binding protein subunit 2 [Rattus norvegicus] 66978 2795.17 7.796666667 8.14 0.062171339 Up 0.157010418 Luc7l Luc7-like K13212|1|1e-101|374|lcm:102346605|RNA-binding protein Luc7-like 2 - - - - 23950 2538.99 51.67333333 50.37333333 -0.036759751 Down 0.156954004 Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 K09512|1|1e-79|300|rno:690183|DnaJ homolog subfamily B member 6 - - - - 67713 738.58 44.01666667 45.30666667 0.041673456 Up 0.156916394 Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 K09539|1|3e-50|200|mmu:67713|DnaJ homolog subfamily C member 19 - - - - 229474 5930 0.213333333 0.146666667 -0.540568381 Down 0.156906992 Fhdc1 FH2 domain containing 1 K04512|1|3e-38|164|cin:100184055|dishevelled associated activator of morphogenesis - GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization gi|50511073|dbj|BAD32522.1|/0/mKIAA1727 protein [Mus musculus] 64424 3547 4.11 3.893333333 -0.078132526 Down 0.156897589 Polr1e polymerase (RNA) I polypeptide E K03005|1|0.0|835|mmu:64424|DNA-directed RNA polymerase I subunit RPA49 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0034062//RNA polymerase activity;GO:0005488//binding;GO:0034062//RNA polymerase activity;GO:0005488//binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|12328816|ref|NP_073722.1|/0/DNA-directed RNA polymerase I subunit RPA49 isoform b [Mus musculus] 69358 881.97 4.233333333 4.016666667 -0.075795351 Down 0.156897589 Lrrc51 leucine rich repeat containing 51 - GO:0044424;GO:0044424;GO:0044424 GO:0008171//O-methyltransferase activity GO:0050954//sensory perception of mechanical stimulus;GO:0042133//neurotransmitter metabolic process;GO:0042491//auditory receptor cell differentiation;GO:0006584//catecholamine metabolic process gi|244790071|ref|NP_081329.1|/4.93286e-106/leucine-rich repeat-containing protein 51 isoform 1 [Mus musculus] 97440 2381.64 3.976666667 4.193333333 0.076537879 Up 0.156897589 B3gnt9 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9" "K18705|1|0.0|701|mmu:97440|beta-1,3-N-acetylglucosaminyltransferase 9 [EC:2.4.1.-]" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane "GO:0016758//transferase activity, transferring hexosyl groups;GO:0016758//transferase activity, transferring hexosyl groups" GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process "gi|30725708|ref|NP_849210.1|/0/UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 precursor [Mus musculus]" 223254 4857 4.04 3.816666667 -0.0820421 Down 0.156897589 Farp1 "FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)" "K17477|1|0.0|2019|mmu:223254|FERM, RhoGEF and pleckstrin domain-containing protein 1" - - - "gi|110349752|ref|NP_598843.3|/0/FERM, RhoGEF and pleckstrin domain-containing protein 1 [Mus musculus]" 338337 4222 3.89 3.67 -0.083990092 Down 0.156897589 Cog3 component of oligomeric golgi complex 3 K20290|1|0.0|1570|mmu:338337|conserved oligomeric Golgi complex subunit 3 GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0000139//Golgi membrane GO:0005488//binding;GO:0022892//substrate-specific transporter activity GO:0006464//cellular protein modification process;GO:0031647//regulation of protein stability;GO:0034613//cellular protein localization;GO:0016482//cytosolic transport;GO:0048193//Golgi vesicle transport;GO:0015031//protein transport "gi|148703879|gb|EDL35826.1|/0/component of oligomeric golgi complex 3, isoform CRA_b [Mus musculus]" 235302 574 0.28 0.356666667 0.349149564 Up 0.156841175 D630033O11Rik RIKEN cDNA D630033O11 gene - - - - gi|343098428|ref|NP_001230190.1|/2.26638e-79/uncharacterized protein LOC235302 [Mus musculus] 194908 1773 0.276666667 0.353333333 0.352881023 Up 0.156841175 Pld6 "phospholipase D family, member 6" K16862|1|2e-42|176|cge:103160650|mitochondrial cardiolipin hydrolase [EC:3.1.4.-] GO:0031966//mitochondrial membrane;GO:0031966//mitochondrial membrane;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane GO:0004620//phospholipase activity;GO:0042802//identical protein binding;GO:0004620//phospholipase activity;GO:0042802//identical protein binding;GO:0004620//phospholipase activity;GO:0042802//identical protein binding GO:0006996//organelle organization;GO:0006306//DNA methylation;GO:0006629//lipid metabolic process;GO:0034660//ncRNA metabolic process;GO:0007281//germ cell development;GO:0048232//male gamete generation;GO:0022403;GO:0006996//organelle organization;GO:0006306//DNA methylation;GO:0006629//lipid metabolic process;GO:0034660//ncRNA metabolic process;GO:0007281//germ cell development;GO:0048232//male gamete generation;GO:0022403;GO:0006996//organelle organization;GO:0006306//DNA methylation;GO:0006629//lipid metabolic process;GO:0034660//ncRNA metabolic process;GO:0007281//germ cell development;GO:0048232//male gamete generation;GO:0022403 gi|27671958|ref|XP_220517.1|/1.77496e-41/PREDICTED: mitochondrial cardiolipin hydrolase isoform X1 [Rattus norvegicus] 229905 2275 13.60666667 14.09 0.05035793 Up 0.156775358 Ccbl2 kynurenine aminotransferase 3 K00816|1|0.0|930|mmu:229905|kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0042802//identical protein binding;GO:0043168//anion binding;GO:0016846//carbon-sulfur lyase activity;GO:0036137;GO:0042802//identical protein binding;GO:0043168//anion binding;GO:0016846//carbon-sulfur lyase activity;GO:0036137 GO:0043648//dicarboxylic acid metabolic process;GO:0006575//cellular modified amino acid metabolic process;GO:0043648//dicarboxylic acid metabolic process;GO:0006575//cellular modified amino acid metabolic process gi|649572289|ref|NP_001280489.1|/0/kynurenine--oxoglutarate transaminase 3 isoform1 [Mus musculus] 22061 2380 0.54 0.45 -0.263034406 Down 0.156728346 Trp63 transformation related protein 63 K10149|1|0.0|1160|myb:102244990|tumor protein p63 GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0032991//macromolecular complex;GO:0005783//endoplasmic reticulum;GO:0000785//chromatin;GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0032991//macromolecular complex;GO:0005783//endoplasmic reticulum;GO:0000785//chromatin;GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0032991//macromolecular complex;GO:0005783//endoplasmic reticulum;GO:0000785//chromatin;GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0032991//macromolecular complex;GO:0005783//endoplasmic reticulum;GO:0000785//chromatin;GO:0031981//nuclear lumen "GO:0043566//structure-specific DNA binding;GO:0005515//protein binding;GO:0000975//regulatory region DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0043169//cation binding;GO:0043566//structure-specific DNA binding;GO:0005515//protein binding;GO:0000975//regulatory region DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0043169//cation binding;GO:0043566//structure-specific DNA binding;GO:0005515//protein binding;GO:0000975//regulatory region DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0043169//cation binding;GO:0043566//structure-specific DNA binding;GO:0005515//protein binding;GO:0000975//regulatory region DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0043169//cation binding;GO:0005515//protein binding;GO:0000975//regulatory region DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding" GO:0008284//positive regulation of cell proliferation;GO:0007498//mesoderm development;GO:0051301//cell division;GO:0043588//skin development;GO:0048232//male gamete generation;GO:0001942//hair follicle development;GO:0009314//response to radiation;GO:0001738//morphogenesis of a polarized epithelium;GO:0007569//cell aging;GO:0051260//protein homooligomerization;GO:0042476//odontogenesis;GO:0012502//induction of programmed cell death;GO:0001649//osteoblast differentiation;GO:0060537//muscle tissue development;GO:0007219//Notch signaling pathway;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030540//female genitalia development;GO:0030216//keratinocyte differentiation;GO:0007267//cell-cell signaling;GO:0006366//transcription from RNA polymerase II promoter;GO:0048483//autonomic nervous system development;GO:0002067//glandular epithelial cell differentiation;GO:0016331//morphogenesis of embryonic epithelium;GO:0035108//limb morphogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0003002//regionalization;GO:0070997//neuron death;GO:0016568//chromatin modification;GO:0001655//urogenital system development;GO:0008284//positive regulation of cell proliferation;GO:0007498//mesoderm development;GO:0051301//cell division;GO:0043588//skin development;GO:0048232//male gamete generation;GO:0001942//hair follicle development;GO:0009314//response to radiation;GO:0001738//morphogenesis of a polarized epithelium;GO:0007569//cell aging;GO:0051260//protein homooligomerization;GO:0042476//odontogenesis;GO:0012502//induction of programmed cell death;GO:0001649//osteoblast differentiation;GO:0060537//muscle tissue development;GO:0007219//Notch signaling pathway;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030540//female genitalia development;GO:0030216//keratinocyte differentiation;GO:0007267//cell-cell signaling;GO:0006366//transcription from RNA polymerase II promoter;GO:0048483//autonomic nervous system development;GO:0002067//glandular epithelial cell differentiation;GO:0016331//morphogenesis of embryonic epithelium;GO:0035108//limb morphogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0003002//regionalization;GO:0070997//neuron death;GO:0016568//chromatin modification;GO:0001655//urogenital system development;GO:0008284//positive regulation of cell proliferation;GO:0007498//mesoderm development;GO:0051301//cell division;GO:0043588//skin development;GO:0048232//male gamete generation;GO:0001942//hair follicle development;GO:0009314//response to radiation;GO:0001738//morphogenesis of a polarized epithelium;GO:0007569//cell aging;GO:0051260//protein homooligomerization;GO:0042476//odontogenesis;GO:0012502//induction of programmed cell death;GO:0001649//osteoblast differentiation;GO:0060537//muscle tissue development;GO:0007219//Notch signaling pathway;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030540//female genitalia development;GO:0030216//keratinocyte differentiation;GO:0007267//cell-cell signaling;GO:0006366//transcription from RNA polymerase II promoter;GO:0048483//autonomic nervous system development;GO:0002067//glandular epithelial cell differentiation;GO:0016331//morphogenesis of embryonic epithelium;GO:0035108//limb morphogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0003002//regionalization;GO:0070997//neuron death;GO:0016568//chromatin modification;GO:0001655//urogenital system development;GO:0008284//positive regulation of cell proliferation;GO:0007498//mesoderm development;GO:0051301//cell division;GO:0043588//skin development;GO:0048232//male gamete generation;GO:0001942//hair follicle development;GO:0009314//response to radiation;GO:0001738//morphogenesis of a polarized epithelium;GO:0007569//cell aging;GO:0051260//protein homooligomerization;GO:0042476//odontogenesis;GO:0012502//induction of programmed cell death;GO:0001649//osteoblast differentiation;GO:0060537//muscle tissue development;GO:0007219//Notch signaling pathway;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030540//female genitalia development;GO:0030216//keratinocyte differentiation;GO:0007267//cell-cell signaling;GO:0006366//transcription from RNA polymerase II promoter;GO:0048483//autonomic nervous system development;GO:0002067//glandular epithelial cell differentiation;GO:0016331//morphogenesis of embryonic epithelium;GO:0035108//limb morphogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0003002//regionalization;GO:0070997//neuron death;GO:0016568//chromatin modification;GO:0001655//urogenital system development;GO:0008284//positive regulation of cell proliferation;GO:0043588//skin development;GO:0001942//hair follicle development;GO:0001738//morphogenesis of a polarized epithelium;GO:0051260//protein homooligomerization;GO:0042476//odontogenesis;GO:0012502//induction of programmed cell death;GO:0060537//muscle tissue development;GO:0007219//Notch signaling pathway;GO:0007568//aging;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030540//female genitalia development;GO:0030216//keratinocyte differentiation;GO:0007267//cell-cell signaling;GO:0006366//transcription from RNA polymerase II promoter;GO:0048483//autonomic nervous system development;GO:0002067//glandular epithelial cell differentiation;GO:0016331//morphogenesis of embryonic epithelium;GO:0035108//limb morphogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0003002//regionalization;GO:0070997//neuron death;GO:0016568//chromatin modification;GO:0001655//urogenital system development gi|803004005|ref|XP_004003091.2|/0/PREDICTED: tumor protein 63 isoform X2 [Ovis aries] 320590 2382 0.533333333 0.446666667 -0.255838904 Down 0.156728346 Svopl SV2 related protein homolog (rat)-like "K06258|1|2e-42|177|tad:TRIADDRAFT_36521|MFS transporter, VNT family, synaptic vesicle glycoprotein 2" GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763 gi|755516918|ref|XP_011239688.1|/0/PREDICTED: putative transporter SVOPL isoform X1 [Mus musculus] 67073 3074 0.526666667 0.44 -0.259386629 Down 0.156728346 Pi4k2b phosphatidylinositol 4-kinase type 2 beta K13711|1|0.0|826|mmu:67073|phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0032550;GO:0052742;GO:0032550;GO:0052742 GO:0046474//glycerophospholipid biosynthetic process;GO:0046474//glycerophospholipid biosynthetic process gi|145966899|ref|NP_080227.2|/0/phosphatidylinositol 4-kinase type 2-beta isoform 1 [Mus musculus] 73422 2682 0.52 0.433333333 -0.263034406 Down 0.156728346 Prox2 prospero homeobox 2 K20212|1|0.0|1087|mmu:73422|prospero homeobox 2 GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|30424822|ref|NP_780407.1|/0/prospero homeobox protein 2 [Mus musculus] 105833 1880 0.156666667 0.226666667 0.53287399 Up 0.156690737 Ccdc65 coiled-coil domain containing 65 K19754|1|6e-19|98.6|amj:102577086|dynein regulatry complex protein 1 - - - "gi|148672227|gb|EDL04174.1|/0/coiled-coil domain containing 65, isoform CRA_b, partial [Mus musculus]" 414872 10654 5.36 5.616666667 0.067481185 Up 0.15666253 Zyg11b "zyg-ll family member B, cell cycle regulator" K10350|1|0.0|1454|mmu:414872|Zyg-11 protein homolog - - - gi|186287294|ref|NP_001028806.2|/0/protein zyg-11 homolog B [Mus musculus] 11787 5822.79 5.72 5.463333333 -0.066233698 Down 0.15666253 Apbb2 "amyloid beta (A4) precursor protein-binding, family B, member 2" K04530|1|0.0|1517|mmu:11787|amyloid beta A4 precursor protein-binding family B member 2 GO:0043231//intracellular membrane-bounded organelle GO:0019899//enzyme binding "GO:0006351//transcription, DNA-templated;GO:0031647//regulation of protein stability;GO:0006928//movement of cell or subcellular component;GO:0006915//apoptotic process;GO:0000084//mitotic S phase;GO:0006935//chemotaxis;GO:0016049//cell growth;GO:0043062//extracellular structure organization" gi|890778122|ref|NP_001297555.1|/0/amyloid beta A4 precursor protein-binding family B member 2 isoform 6 [Mus musculus] 320706 13232 5.533333333 5.276666667 -0.068521986 Down 0.15666253 Soga1 "suppressor of glucose, autophagy associated 1" K01895|1|2e-86|325|apla:101803542|acetyl-CoA synthetase [EC:6.2.1.1];K17785|2|4e-08|65.5|nvi:100118032|mitofilin;K20072|3|6e-07|61.6|xtr:100135363|switch-associated protein 70;K16469|4|6e-07|61.6|mmu:230872|rootletin;K10388|5|8e-07|61.2|asn:102376562|plectin - - - gi|257467641|ref|NP_001158135.1|/0/protein SOGA1 [Mus musculus] 56480 3031 5.466666667 5.723333333 0.066194224 Up 0.15666253 Tbk1 TANK-binding kinase 1 K05410|1|0.0|1439|mmu:56480|TANK-binding kinase 1 [EC:2.7.11.10] GO:0044424 GO:0032550;GO:0005515//protein binding;GO:0004672//protein kinase activity GO:0002253//activation of immune response;GO:0032481//positive regulation of type I interferon production;GO:0006366//transcription from RNA polymerase II promoter;GO:0042742//defense response to bacterium;GO:0006796//phosphate-containing compound metabolic process;GO:0002252;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006464//cellular protein modification process;GO:0042108//positive regulation of cytokine biosynthetic process "gi|148692474|gb|EDL24421.1|/0/TANK-binding kinase 1, isoform CRA_b, partial [Mus musculus]" 100210 1356 5.163333333 4.903333333 -0.074539898 Down 0.15666253 Gpn2 GPN-loop GTPase 2 K06883|1|7e-164|579|mmu:100210|uncharacterized protein - GO:0032550 - gi|595582150|ref|NP_001277671.1|/1.30821e-148/GPN-loop GTPase 2 isoform 2 [Mus musculus] 12982 1850 5.326666667 5.07 -0.071247255 Down 0.15666253 Csf2ra "colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)" K05066|1|0.0|721|mmu:12982|granulocyte-macrophage colony-stimulating factor receptor alpha - - GO:0097305//response to alcohol gi|755562735|ref|XP_011245435.1|/0/PREDICTED: granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X4 [Mus musculus] 170762 6420 1.543333333 1.406666667 -0.133769195 Down 0.156643725 Nup155 nucleoporin 155 K14312|1|0.0|2612|mmu:170762|nuclear pore complex protein Nup155 GO:0005635//nuclear envelope GO:0022829//wide pore channel activity;GO:0005198//structural molecule activity GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0006405//RNA export from nucleus;GO:0006997//nucleus organization;GO:0006886//intracellular protein transport gi|37360098|dbj|BAC98027.1|/0/mKIAA0791 protein [Mus musculus] 103537 5231 1.523333333 1.663333333 0.12684565 Up 0.156643725 Mbtd1 mbt domain containing 1 K11465|1|4e-31|140|tup:102500909|sex comb on midleg-like protein 2;K11461|4|2e-30|138|crg:105333401|polycomb protein SCMH1 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" "gi|148683957|gb|EDL15904.1|/0/mCG1463, isoform CRA_b, partial [Mus musculus]" 272158 2940 1.63 1.493333333 -0.126335733 Down 0.156643725 Poln DNA polymerase N K16618|1|0.0|1608|mmu:272158|DNA polymerase nu [EC:2.7.7.7] - - GO:0006259//DNA metabolic process gi|577019504|ref|NP_001276732.1|/0/DNA polymerase nu isoform 2 [Mus musculus] 78586 3530 2.18 2.02 -0.109972842 Down 0.156634322 Srbd1 S1 RNA binding domain 1 K11292|1|4e-12|77.0|bfo:BRAFLDRAFT_128224|transcription elongation factor SPT6 - - - gi|226443099|ref|NP_084409.3|/0/S1 RNA-binding domain-containing protein 1 [Mus musculus] 269033 2291 0.71 0.61 -0.219009782 Down 0.156615518 4930503L19Rik RIKEN cDNA 4930503L19 gene - - - - "gi|148677635|gb|EDL09582.1|/0/RIKEN cDNA 4930503L19, isoform CRA_e, partial [Mus musculus]" 70281 1121 0.72 0.616666667 -0.223506042 Down 0.156615518 2310068J16Rik RIKEN cDNA 2310068J16 gene - - - - gi|148672159|gb|EDL04106.1|/4.05481e-39/mCG147116 [Mus musculus] 11538 4951.08 0.726666667 0.623333333 -0.221289865 Down 0.156615518 Adnp activity-dependent neuroprotective protein - GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044421;GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044421;GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044421 GO:0001071//nucleic acid binding transcription factor activity;GO:0033218//amide binding;GO:0003677//DNA binding;GO:0015631//tubulin binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0033218//amide binding;GO:0003677//DNA binding;GO:0015631//tubulin binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0033218//amide binding;GO:0003677//DNA binding;GO:0015631//tubulin binding;GO:0046914//transition metal ion binding "GO:0033483;GO:0006471//protein ADP-ribosylation;GO:0007416//synapse assembly;GO:0007268//chemical synaptic transmission;GO:0007613//memory;GO:0006351//transcription, DNA-templated;GO:0010033//response to organic substance;GO:0010975//regulation of neuron projection development;GO:0030307//positive regulation of cell growth;GO:0043393//regulation of protein binding;GO:0006182//cGMP biosynthetic process;GO:0022602//ovulation cycle process;GO:0043066//negative regulation of apoptotic process;GO:0045860//positive regulation of protein kinase activity;GO:0033483;GO:0006471//protein ADP-ribosylation;GO:0007416//synapse assembly;GO:0007268//chemical synaptic transmission;GO:0007613//memory;GO:0006351//transcription, DNA-templated;GO:0010033//response to organic substance;GO:0010975//regulation of neuron projection development;GO:0030307//positive regulation of cell growth;GO:0043393//regulation of protein binding;GO:0006182//cGMP biosynthetic process;GO:0022602//ovulation cycle process;GO:0043066//negative regulation of apoptotic process;GO:0045860//positive regulation of protein kinase activity;GO:0033483;GO:0006471//protein ADP-ribosylation;GO:0007416//synapse assembly;GO:0007268//chemical synaptic transmission;GO:0007613//memory;GO:0006351//transcription, DNA-templated;GO:0010033//response to organic substance;GO:0010975//regulation of neuron projection development;GO:0030307//positive regulation of cell growth;GO:0043393//regulation of protein binding;GO:0006182//cGMP biosynthetic process;GO:0022602//ovulation cycle process;GO:0043066//negative regulation of apoptotic process;GO:0045860//positive regulation of protein kinase activity" gi|37360092|dbj|BAC98024.1|/0/mKIAA0784 protein [Mus musculus] 76967 5499 0.72 0.62 -0.215728691 Down 0.156615518 2700049A03Rik RIKEN cDNA 2700049A03 gene - GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center - GO:0016043//cellular component organization;GO:0016043//cellular component organization gi|254540144|ref|NP_084094.1|/0/protein TALPID3 isoform 2 [Mus musculus] 213056 8625 0.576666667 0.673333333 0.223583255 Up 0.156615518 Fam126b "family with sequence similarity 126, member B" K00605|1|8e-11|73.9|tsp:Tsp_07633|aminomethyltransferase [EC:2.1.2.10] GO:0044464 - - "gi|148667670|gb|EDL00087.1|/0/cDNA sequence BC049806, isoform CRA_b, partial [Mus musculus]" 234728 3577 0.59 0.686666667 0.218894977 Up 0.156615518 Cmtr2 cap methyltransferase 2 K14590|1|0.0|1563|mmu:234728|cap2 methyltransferase [EC:2.1.1.296] GO:0031224//intrinsic component of membrane GO:0016741 GO:0008152//metabolic process gi|31981920|ref|NP_666327.2|/0/cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 [Mus musculus] 142687 1939.5 42.80333333 44.05666667 0.041637193 Up 0.156606115 Asb14 ankyrin repeat and SOCS box-containing 14 K10336|1|0.0|1149|mmu:142687|ankyrin repeat and SOCS box protein 14 - - - gi|282721040|ref|NP_543132.3|/0/ankyrin repeat and SOCS box protein 14 isoform 2 [Mus musculus] 53896 1967 0.823333333 0.936666667 0.186059089 Up 0.156493287 Slc7a10 "solute carrier family 7 (cationic amino acid transporter, y+ system), member 10" "K13782|1|0.0|981|mmu:53896|solute carrier family 7 (L-type amino acid transporter), member 10" GO:0043005//neuron projection;GO:0016021//integral component of membrane GO:0005488//binding;GO:0015179//L-amino acid transmembrane transporter activity;GO:0022889 GO:0015807//L-amino acid transport;GO:0032329;GO:0032328//alanine transport gi|229092254|ref|NP_059090.3|/0/asc-type amino acid transporter 1 [Mus musculus] 114643 2286 0.776666667 0.883333333 0.185662405 Up 0.156493287 Oas1c 2'-5' oligoadenylate synthetase 1C K14216|1|7e-118|427|mmu:246730|2'-5'-oligoadenylate synthetase [EC:2.7.7.84] GO:0044424 GO:0032550;GO:0003723//RNA binding;GO:0030234//enzyme regulator activity;GO:0070566//adenylyltransferase activity GO:0008585//female gonad development;GO:0043086//negative regulation of catalytic activity;GO:0002252 gi|15809044|ref|NP_291019.1|/0/2'-5' oligoadenylate synthetase 1C [Mus musculus] 330119 7579.53 0.786666667 0.896666667 0.188819313 Up 0.156493287 Adamts3 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3" K08619|1|0.0|2433|mmu:330119|a disintegrin and metalloproteinase with thrombospondin motifs 3 [EC:3.4.24.-] - "GO:0043169//cation binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0043169//cation binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0007166//cell surface receptor signaling pathway;GO:0051604//protein maturation;GO:0007166//cell surface receptor signaling pathway;GO:0051604//protein maturation gi|124487141|ref|NP_001074870.1|/0/A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform 2 precursor [Mus musculus] 12123 5366 0.16 0.23 0.523561956 Up 0.156446275 Hrk "harakiri, BCL2 interacting protein (contains only BH3 domain)" K02512|1|5e-10|70.5|rno:117271|activator of apoptosis harakiri - - - "gi|148687850|gb|EDL19797.1|/3.16607e-34/harakiri, BCL2 interacting protein (contains only BH3 domain), partial [Mus musculus]" 15494 1490 0.153333333 0.22 0.520832163 Up 0.156446275 Hsd3b3 "hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3" K00070|1|0.0|701|mmu:15493|3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1] GO:0031224//intrinsic component of membrane;GO:0005740//mitochondrial envelope;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0005740//mitochondrial envelope;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0005740//mitochondrial envelope;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0005740//mitochondrial envelope;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0005740//mitochondrial envelope;GO:0019866//organelle inner membrane "GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds;GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0036094//small molecule binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds;GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0036094//small molecule binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds;GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0036094//small molecule binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds;GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0036094//small molecule binding;GO:0016863//intramolecular oxidoreductase activity, transposing C=C bonds" GO:0003006//developmental process involved in reproduction;GO:0006694//steroid biosynthetic process;GO:0006826//iron ion transport;GO:0051384//response to glucocorticoid;GO:0021543//pallium development;GO:0010038//response to metal ion;GO:0003006//developmental process involved in reproduction;GO:0006694//steroid biosynthetic process;GO:0006826//iron ion transport;GO:0051384//response to glucocorticoid;GO:0021543//pallium development;GO:0010038//response to metal ion;GO:0003006//developmental process involved in reproduction;GO:0006694//steroid biosynthetic process;GO:0006826//iron ion transport;GO:0051384//response to glucocorticoid;GO:0021543//pallium development;GO:0010038//response to metal ion;GO:0003006//developmental process involved in reproduction;GO:0006694//steroid biosynthetic process;GO:0006826//iron ion transport;GO:0051384//response to glucocorticoid;GO:0021543//pallium development;GO:0010038//response to metal ion;GO:0003006//developmental process involved in reproduction;GO:0006694//steroid biosynthetic process;GO:0006826//iron ion transport;GO:0051384//response to glucocorticoid;GO:0021543//pallium development;GO:0010038//response to metal ion "gi|148707023|gb|EDL38970.1|/0/mCG140534, isoform CRA_b, partial [Mus musculus]" 56384 3480 50.65666667 49.44 -0.035073404 Down 0.156418068 Letm1 leucine zipper-EF-hand containing transmembrane protein 1 "K17800|1|0.0|1065|mmu:56384|LETM1 and EF-hand domain-containing protein 1, mitochondrial" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0043169//cation binding GO:0007007//inner mitochondrial membrane organization "gi|33416528|gb|AAH55865.1|/0/Letm1 protein, partial [Mus musculus]" 211286 2447 12.71666667 12.24333333 -0.054724161 Down 0.15638986 Cln5 "ceroid-lipofuscinosis, neuronal 5" K12390|1|0.0|701|mmu:211286|ceroid-lipofuscinosis neuronal protein 5 GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0044437 - GO:0050953//sensory perception of light stimulus;GO:0007399//nervous system development;GO:0016485//protein processing;GO:0044723;GO:0035751//regulation of lysosomal lumen pH gi|112734833|ref|NP_001028414.1|/0/ceroid-lipofuscinosis neuronal protein 5 homolog precursor [Mus musculus] 67117 2153 13.17 13.64333333 0.05094082 Up 0.15638986 Dynlt3 dynein light chain Tctex-type 3 K10420|1|4e-64|248|mmu:67117|dynein light chain Tctex-type 1 GO:0030286//dynein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000776//kinetochore;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0005515//protein binding GO:0000087//mitotic M phase;GO:0051234//establishment of localization gi|880938694|ref|XP_005080633.2|/1.15054e-63/PREDICTED: dynein light chain Tctex-type 3 [Mesocricetus auratus] 78251 3970 0.156666667 0.223333333 0.511500339 Up 0.156352251 Zfp712 zinc finger protein 712 K09228|1|0.0|1542|mmu:78251|KRAB domain-containing zinc finger protein - - - "gi|148678380|gb|EDL10327.1|/0/mCG67989, partial [Mus musculus]" 382252 3366 0.363333333 0.286666667 -0.34191957 Down 0.156286434 A830080D01Rik RIKEN cDNA A830080D01 gene K13112|1|8e-22|108|xla:399219|thyroid hormone receptor-associated protein 3 GO:0043231//intracellular membrane-bounded organelle - - gi|115511062|ref|NP_001028644.2|/0/uncharacterized protein CXorf23 homolog [Mus musculus] 228413 2846 0.07 0.02 -1.807354922 Down 0.156286434 Prrg4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) K01321|1|2e-09|67.8|clv:102088048|coagulation factor IX (Christmas factor) [EC:3.4.21.22];K01320|2|2e-09|67.8|hsa:2155|coagulation factor VII [EC:3.4.21.21];K01314|3|2e-09|67.4|xma:102224608|coagulation factor X [EC:3.4.21.6] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding - gi|224994242|ref|NP_848810.3|/3.52099e-119/transmembrane gamma-carboxyglutamic acid protein 4 precursor [Mus musculus] 433470 672 0.383333333 0.303333333 -0.337695411 Down 0.156286434 AA467197 expressed sequence AA467197 K03948|1|3e-06|54.3|tru:101067126|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4 GO:0043231//intracellular membrane-bounded organelle - - gi|51921341|ref|NP_001004174.1|/7.23957e-37/normal mucosa of esophagus-specific gene 1 protein [Mus musculus] 237397 6764 0.016666667 0.063333333 1.925999419 Up 0.156286434 C2cd4c C2 calcium-dependent domain containing 4C K15290|1|5e-08|64.3|crg:105338029|synaptotagmin-1;K19328|3|3e-07|61.6|tru:101074161|synaptotagmin-14/16 - - - gi|58037552|ref|NP_941016.2|/0/C2 calcium-dependent domain-containing protein 4C [Mus musculus] 244682 3606 0.313333333 0.396666667 0.340228912 Up 0.156286434 Cntn5 contactin 5 K06763|1|0.0|1731|mmu:244682|contactin 5 - - - - 54651 3240 0.3 0.38 0.341036918 Up 0.156286434 Usp27x "ubiquitin specific peptidase 27, X chromosome" K11366|1|0.0|1155|rno:302566|ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12] - - - "gi|229597175|gb|AAI37613.1|/0/Usp27x protein, partial [Mus musculus]" 217558 6352 0.376666667 0.296666667 -0.344445531 Down 0.156286434 G2e3 G2/M-phase specific E3 ubiquitin ligase K19998|1|7e-139|498|apla:101795279|sec1 family domain-containing protein 1;K08592|3|1e-34|152|api:100574671|sentrin-specific protease 1 [EC:3.4.22.68];K18494|4|5e-09|67.4|fab:101812936|histone-lysine N-methyltransferase SETDB2 [EC:2.1.1.43];K09186|5|7e-09|67.0|lcm:102357046|histone-lysine N-methyltransferase MLL1 [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0001701//in utero embryonic development;GO:0036211//protein modification process;GO:0006915//apoptotic process;GO:0001701//in utero embryonic development;GO:0036211//protein modification process;GO:0006915//apoptotic process;GO:0001701//in utero embryonic development;GO:0036211//protein modification process;GO:0006915//apoptotic process gi|37360328|dbj|BAC98142.1|/0/mKIAA1333 protein [Mus musculus] 243369 15586 0.07 0.02 -1.807354922 Down 0.156286434 Sspo SCO-spondin K03900|1|1e-168|598|xtr:100492314|von Willebrand factor GO:0044424 - GO:0022610 gi|345842432|ref|NP_775604.3|/0/SCO-spondin precursor [Mus musculus] 211064 1968 2.52 2.693333333 0.095969059 Up 0.156248825 Alkbh1 "alkB homolog 1, histone H2A dioxygenase" K10765|1|0.0|779|mmu:211064|alkylated DNA repair protein alkB homolog 1 [EC:1.14.11.- 4.2.99.18] - - - - 71946 4470 2.543333333 2.37 -0.101833497 Down 0.156248825 Endod1 endonuclease domain containing 1 K15049|1|0.0|910|mmu:71946|endonuclease domain-containing 1 protein - - - gi|50510657|dbj|BAD32314.1|/0/mKIAA0830 protein [Mus musculus] 16319 3217 2.366666667 2.536666667 0.100077429 Up 0.156248825 Incenp inner centromere protein K11515|1|0.0|812|mmu:16319|inner centromere protein "GO:0000775//chromosome, centromeric region;GO:0032991//macromolecular complex;GO:0000795//synaptonemal complex;GO:0015630//microtubule cytoskeleton" - GO:0000087//mitotic M phase gi|755562821|ref|XP_006526771.2|/0/PREDICTED: inner centromere protein isoform X2 [Mus musculus] 23967 2027 2.596666667 2.43 -0.095704514 Down 0.156248825 Osr1 odd-skipped related 1 (Drosophila) K09215|1|1e-145|519|rno:298878|odd-skipped GO:0031981//nuclear lumen GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding GO:0030326//embryonic limb morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0006915//apoptotic process;GO:0010463//mesenchymal cell proliferation;GO:0007369//gastrulation;GO:0008284//positive regulation of cell proliferation;GO:0007498//mesoderm development;GO:0030282//bone mineralization;GO:0072098;GO:0072075//metanephric mesenchyme development;GO:0042471//ear morphogenesis;GO:0072160//nephron tubule epithelial cell differentiation;GO:0072141//renal interstitial fibroblast development;GO:0006366//transcription from RNA polymerase II promoter;GO:0032526//response to retinoic acid;GO:0072171;GO:0072012//glomerulus vasculature development gi|6754928|ref|NP_035989.1|/1.23529e-144/protein odd-skipped-related 1 [Mus musculus] 225020 2065.7 45.62333333 46.8 0.036736673 Up 0.156117191 Fez2 fasciculation and elongation protein zeta 2 (zygin II) K16502|1|7e-64|248|acs:100557797|cadherin-related family member 2 - - - gi|552953739|ref|NP_001272878.1|/1.39941e-142/fasciculation and elongation protein zeta-2 isoform 4 [Mus musculus] 224997 5306 0.073333333 0.023333333 -1.652076697 Down 0.156098387 Dlgap1 "discs, large (Drosophila) homolog-associated protein 1" "K15008|1|0.0|1706|mmu:224997|discs, large-associated protein 1" GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane GO:0005515//protein binding;GO:0005515//protein binding;GO:0005488//binding GO:0010498//proteasomal protein catabolic process;GO:0007267//cell-cell signaling;GO:0070841;GO:0008104//protein localization;GO:0010498//proteasomal protein catabolic process;GO:0007267//cell-cell signaling;GO:0070841;GO:0008104//protein localization;GO:0007267//cell-cell signaling gi|189491682|ref|NP_001121653.1|/0/disks large-associated protein 1 isoform 4 [Mus musculus] 268345 6196 0.02 0.066666667 1.736965594 Up 0.156098387 Kcnc2 "potassium voltage gated channel, Shaw-related subfamily, member 2" K04888|1|0.0|1031|mmu:268345|potassium voltage-gated channel Shaw-related subfamily C member 2 - - - "gi|148689808|gb|EDL21755.1|/0/potassium voltage gated channel, Shaw-related subfamily, member 2, isoform CRA_e, partial [Mus musculus]" 329782 3124 0.076666667 0.023333333 -1.716207034 Down 0.156098387 4930570G19Rik RIKEN cDNA 4930570G19 gene - - - - "gi|148679924|gb|EDL11871.1|/1.34109e-24/mCG1045702, isoform CRA_a, partial [Mus musculus]" 18040 3244 0.023333333 0.07 1.584962501 Up 0.156098387 Nefm "neurofilament, medium polypeptide" K04573|1|0.0|751|mmu:18040|neurofilament medium polypeptide (neurofilament 3) GO:0043005//neuron projection;GO:0045202//synapse;GO:0005882//intermediate filament - GO:0032536//regulation of cell projection size;GO:0022607//cellular component assembly;GO:0045104//intermediate filament cytoskeleton organization;GO:0010970//transport along microtubule gi|829732323|ref|XP_012637563.1|/0/PREDICTED: neurofilament medium polypeptide [Microcebus murinus] 230576 2535 0.08 0.026666667 -1.584962501 Down 0.156098387 Ttc22 tetratricopeptide repeat domain 22 - - - - gi|29244092|ref|NP_808335.1|/0/tetratricopeptide repeat protein 22 [Mus musculus] 22780 4098 0.02 0.066666667 1.736965594 Up 0.156098387 Ikzf3 IKAROS family zinc finger 3 K09220|1|0.0|1055|mmu:22780|IKAROS family zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0046983//protein dimerization activity "GO:0006915//apoptotic process;GO:0030183//B cell differentiation;GO:0006351//transcription, DNA-templated;GO:0042100//B cell proliferation" gi|113374152|ref|NP_035901.1|/0/zinc finger protein Aiolos [Mus musculus] 242509 6453 0.07 0.023333333 -1.584962501 Down 0.156098387 Bnc2 basonuclin 2 - - - - gi|268830542|ref|NP_766458.3|/0/zinc finger protein basonuclin-2 [Mus musculus] 76373 3025 0.023333333 0.076666667 1.716207034 Up 0.156098387 Zfp773 zinc finger protein 773 K09228|1|0.0|938|mmu:76373|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|256773193|ref|NP_083860.1|/0/zinc finger protein LOC76373 [Mus musculus] 18016 4771.05 42.14666667 40.97666667 -0.040615904 Down 0.156060777 Nf2 neurofibromatosis 2 K16684|1|0.0|936|mmu:18016|merlin GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0070161;GO:0015629//actin cytoskeleton;GO:0032155;GO:0031252//cell leading edge;GO:0044425;GO:0005768//endosome;GO:0042995//cell projection;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0070161;GO:0015629//actin cytoskeleton;GO:0032155;GO:0031252//cell leading edge;GO:0044425;GO:0005768//endosome;GO:0042995//cell projection;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0070161;GO:0015629//actin cytoskeleton;GO:0032155;GO:0031252//cell leading edge;GO:0044425;GO:0005768//endosome;GO:0042995//cell projection GO:0005102//receptor binding;GO:0005102//receptor binding;GO:0005102//receptor binding GO:0032233//positive regulation of actin filament bundle assembly;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0009888//tissue development;GO:0034330;GO:0014009//glial cell proliferation;GO:0042476//odontogenesis;GO:0007162//negative regulation of cell adhesion;GO:0002088//lens development in camera-type eye;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0001933//negative regulation of protein phosphorylation;GO:0000165//MAPK cascade;GO:0009966//regulation of signal transduction;GO:0016049//cell growth;GO:0006260//DNA replication;GO:0032233//positive regulation of actin filament bundle assembly;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0009888//tissue development;GO:0034330;GO:0014009//glial cell proliferation;GO:0042476//odontogenesis;GO:0007162//negative regulation of cell adhesion;GO:0002088//lens development in camera-type eye;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0001933//negative regulation of protein phosphorylation;GO:0000165//MAPK cascade;GO:0009966//regulation of signal transduction;GO:0016049//cell growth;GO:0006260//DNA replication;GO:0032233//positive regulation of actin filament bundle assembly;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0009888//tissue development;GO:0034330;GO:0014009//glial cell proliferation;GO:0042476//odontogenesis;GO:0007162//negative regulation of cell adhesion;GO:0002088//lens development in camera-type eye;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0001933//negative regulation of protein phosphorylation;GO:0000165//MAPK cascade;GO:0009966//regulation of signal transduction;GO:0016049//cell growth;GO:0006260//DNA replication;GO:0001704//formation of primary germ layer gi|31982775|ref|NP_035028.2|/0/merlin isoform 2 [Mus musculus] 19192 2620 44.23 45.39666667 0.037561127 Up 0.156060777 Psme3 "proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)" K06698|1|2e-139|499|pale:102877699|proteasome activator subunit 3 (PA28 gamma) GO:0031981//nuclear lumen;GO:0022624//proteasome accessory complex;GO:0044444//cytoplasmic part GO:0061135;GO:0005515//protein binding;GO:0016787//hydrolase activity "GO:0010952//positive regulation of peptidase activity;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0006915//apoptotic process;GO:0044764;GO:0051320;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|6755214|ref|NP_035322.1|/1.80586e-138/proteasome activator complex subunit 3 [Mus musculus] 13589 7330 8.36 8.033333333 -0.057504202 Down 0.156023167 Mapre1 "microtubule-associated protein, RP/EB family, member 1" "K10436|1|2e-142|511|mmu:13589|microtubule-associated protein, RP/EB family" GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005874//microtubule;GO:0044459;GO:0044444//cytoplasmic part GO:0008017//microtubule binding GO:0044772//mitotic cell cycle phase transition;GO:0031111//negative regulation of microtubule polymerization or depolymerization;GO:0007067//mitotic nuclear division;GO:0072698 "gi|30851559|gb|AAH52405.1|/4.41673e-143/Mapre1 protein, partial [Mus musculus]" 109093 1880 8.53 8.196666667 -0.057508412 Down 0.156023167 Rars2 "arginyl-tRNA synthetase 2, mitochondrial" K01887|1|0.0|1111|mmu:109093|arginyl-tRNA synthetase [EC:6.1.1.19] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation "gi|240120047|ref|NP_852071.2|/0/probable arginine--tRNA ligase, mitochondrial precursor [Mus musculus]" 54364 1172 7.36 7.69 0.063277832 Up 0.156023167 Rpp30 ribonuclease P/MRP 30 subunit K03539|1|5e-149|529|mmu:54364|ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] GO:0043231//intracellular membrane-bounded organelle GO:0004549//tRNA-specific ribonuclease activity GO:0006399//tRNA metabolic process gi|257196209|ref|NP_062301.3|/4.33291e-148/ribonuclease P protein subunit p30 [Mus musculus] 212307 4025.18 42.24333333 41.08666667 -0.040053389 Down 0.155929144 Mapre2 "microtubule-associated protein, RP/EB family, member 2" "K10436|1|2e-129|466|cfa:490487|microtubule-associated protein, RP/EB family" GO:0015630//microtubule cytoskeleton GO:0015631//tubulin binding GO:0000087//mitotic M phase gi|664740724|ref|XP_008527664.1|/6.76632e-151/PREDICTED: microtubule-associated protein RP/EB family member 2 isoform X1 [Equus przewalskii] 76088 7810 3.04 3.226666667 0.085973223 Up 0.155910339 Dock8 dedicator of cytokinesis 8 K05727|1|4e-14|84.7|oas:101114650|dedicator of cytokinesis protein 3;K13708|4|3e-13|81.6|crg:105338650|dedicator of cytokinesis protein 1 - GO:0030695//GTPase regulator activity GO:0035556//intracellular signal transduction gi|62241030|ref|NP_083061.2|/0/dedicator of cytokinesis protein 8 [Mus musculus] 103737 2726 2.97 3.163333333 0.090982655 Up 0.155910339 Pex12 peroxisomal biogenesis factor 12 K13345|1|0.0|729|mmu:103737|peroxin-12 GO:0031231//intrinsic component of peroxisomal membrane GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0006625//protein targeting to peroxisome "gi|148683752|gb|EDL15699.1|/0/peroxisomal biogenesis factor 12, isoform CRA_b, partial [Mus musculus]" 17454 3599.84 3.133333333 2.94 -0.091882101 Down 0.155910339 Mov10 Moloney leukemia virus 10 K18422|1|0.0|1918|mmu:17454|helicase MOV-10 [EC:3.6.4.13] GO:0035770//ribonucleoprotein granule;GO:0035770//ribonucleoprotein granule;GO:0035770//ribonucleoprotein granule GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0003676//nucleic acid binding GO:0006379//mRNA cleavage;GO:0016458//gene silencing;GO:0006379//mRNA cleavage;GO:0016458//gene silencing;GO:0006379//mRNA cleavage;GO:0016458//gene silencing gi|50511033|dbj|BAD32502.1|/0/mKIAA1631 protein [Mus musculus] 65103 2553 3.05 2.86 -0.092794096 Down 0.155910339 Arl6ip6 ADP-ribosylation factor-like 6 interacting protein 6 - GO:0031224//intrinsic component of membrane - - gi|254281227|ref|NP_075365.3|/9.37024e-108/ADP-ribosylation factor-like protein 6-interacting protein 6 [Mus musculus] 64095 3936 0.226666667 0.16 -0.502500341 Down 0.155910339 Gpr35 G protein-coupled receptor 35 K04276|1|9e-164|580|mmu:64095|G protein-coupled receptor 35 GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway gi|568909467|ref|XP_006529841.1|/1.63662e-165/PREDICTED: G-protein coupled receptor 35 isoform X3 [Mus musculus] 67698 2107 12.90666667 13.37 0.050883014 Up 0.155900936 Fam174a "family with sequence similarity 174, member A" - GO:0016020//membrane - - gi|261278096|dbj|BAI44634.1|/1.37228e-69/NAA6 protein [Mus musculus] 108156 3324 14.49 14.03 -0.046542586 Down 0.155900936 Mthfd1 "methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase" K00288|1|0.0|1734|mmu:108156|methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3] - - - "gi|148704520|gb|EDL36467.1|/0/methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase, isoform CRA_b, partial [Mus musculus]" 78244 2053 13.51 13.04666667 -0.050346419 Down 0.155900936 Dnajc21 DnaJ heat shock protein family (Hsp40) member C21 K09506|1|0.0|932|mmu:78244|DnaJ homolog subfamily A member 5 - - - - 57274 1887 0.313333333 0.393333333 0.328054198 Up 0.155722291 Slc16a8 "solute carrier family 16 (monocarboxylic acid transporters), member 8" "K08185|1|0.0|732|mmu:57274|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 8" GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane GO:0015291//secondary active transmembrane transporter activity;GO:0008028//monocarboxylic acid transmembrane transporter activity GO:0044763;GO:0032787//monocarboxylic acid metabolic process;GO:0002376//immune system process;GO:0007599//hemostasis;GO:0015727//lactate transport gi|10048452|ref|NP_065262.1|/0/monocarboxylate transporter 3 [Mus musculus] 80986 2601 0.393333333 0.313333333 -0.328054198 Down 0.155722291 Ckap2 cytoskeleton associated protein 2 K16769|1|0.0|1278|mmu:80986|cytoskeleton-associated protein 2 GO:0005815//microtubule organizing center;GO:0005874//microtubule - GO:0012501//programmed cell death;GO:0007019//microtubule depolymerization;GO:0006366//transcription from RNA polymerase II promoter gi|269315836|ref|NP_001004140.2|/0/cytoskeleton-associated protein 2 [Mus musculus] 29864 2132 44.50333333 45.64666667 0.036596113 Up 0.155712889 Rnf11 ring finger protein 11 K11980|1|8e-75|284|mmu:29864|E3 ubiquitin-protein ligase RNF11 GO:0005768//endosome;GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0019941//modification-dependent protein catabolic process;GO:0016567//protein ubiquitination gi|12004970|gb|AAG44245.1|/8.66036e-80/Nedd4 WW domain-binding protein 2 [Mus musculus] 272009 2939 0.01 0.053333333 2.415037499 Up 0.155656474 Srsf12 serine/arginine-rich splicing factor 12 - - - - gi|240255626|ref|NP_808442.2|/1.08932e-38/serine/arginine-rich splicing factor 12 [Mus musculus] 433294 1086 0.053333333 0.01 -2.415037499 Down 0.155656474 Mettl21c methyltransferase like 21C K02357|1|2e-14|82.8|pale:102895576|elongation factor Ts - - - - 328747 1179 0.05 0.01 -2.321928095 Down 0.155656474 Gm5091 predicted gene 5091 - - - - - 100502950 1152 0.01 0.05 2.321928095 Up 0.155656474 Gm3336 predicted gene 3336 - - - - "gi|148696914|gb|EDL28861.1|/5.28869e-66/mCG14782, isoform CRA_a, partial [Mus musculus]" 24102 1034 0.01 0.053333333 2.415037499 Up 0.155656474 Trex2 three prime repair exonuclease 2 K10791|1|3e-135|483|mmu:24102|three prime repair exonuclease 2 [EC:3.1.11.2] GO:0043231//intracellular membrane-bounded organelle "GO:0016895//exodeoxyribonuclease activity, producing 5'-phosphomonoesters" GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress gi|6755877|ref|NP_036037.1|/2.25097e-134/three prime repair exonuclease 2 [Mus musculus] 53897 1969 0.01 0.053333333 2.415037499 Up 0.155656474 Gal3st1 galactose-3-O-sulfotransferase 1 K01019|1|0.0|825|rno:683713|galactosylceramide sulfotransferase [EC:2.8.2.11] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0050694//galactose 3-O-sulfotransferase activity;GO:0050694//galactose 3-O-sulfotransferase activity;GO:0050694//galactose 3-O-sulfotransferase activity GO:0008366//axon ensheathment;GO:0006681//galactosylceramide metabolic process;GO:0048232//male gamete generation;GO:0008366//axon ensheathment;GO:0006681//galactosylceramide metabolic process;GO:0048232//male gamete generation;GO:0008366//axon ensheathment;GO:0006681//galactosylceramide metabolic process;GO:0048232//male gamete generation gi|31980855|ref|NP_058618.2|/0/galactosylceramide sulfotransferase [Mus musculus] 117148 1971 0.01 0.05 2.321928095 Up 0.155656474 Necab2 N-terminal EF-hand calcium binding protein 2 - GO:0044424 GO:0046872//metal ion binding GO:0019932//second-messenger-mediated signaling gi|16905129|ref|NP_473436.1|/0/N-terminal EF-hand calcium-binding protein 2 [Mus musculus] 381484 913 0.01 0.053333333 2.415037499 Up 0.155656474 Gm5150 predicted gene 5150 K06551|1|6e-56|219|ssc:100626120|signal-regulatory protein alpha/beta1/gamma;K16827|4|2e-50|201|ptg:102967165|signal-regulatory protein delta - - - gi|126157464|ref|NP_001075156.1|/1.48642e-144/uncharacterized protein LOC381484 precursor [Mus musculus] 100503895 1093 0.01 0.05 2.321928095 Up 0.155656474 Tpsab1 tryptase alpha/beta 1 K01340|1|6e-127|424|mmu:100503895|tryptase [EC:3.4.21.59] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process "gi|148690474|gb|EDL22421.1|/2.4618e-126/tryptase alpha/beta 1, isoform CRA_c, partial [Mus musculus]" 319646 1749 0.01 0.05 2.321928095 Up 0.155656474 D630013N20Rik RIKEN cDNA D630013N20 gene - - - - - 20204 1150 0.053333333 0.01 -2.415037499 Down 0.155656474 Prrx2 paired related homeobox 2 K09329|1|3e-69|264|mmu:20204|paired mesoderm homeobox protein GO:0043229//intracellular organelle GO:0019904//protein domain specific binding GO:0035108//limb morphogenesis;GO:0007224//smoothened signaling pathway;GO:0042471//ear morphogenesis;GO:0048514//blood vessel morphogenesis;GO:0048704//embryonic skeletal system morphogenesis "gi|148676546|gb|EDL08493.1|/2.51525e-68/paired related homeobox 2, partial [Mus musculus]" 66931 1878 0.01 0.05 2.321928095 Up 0.155656474 1700010I14Rik RIKEN cDNA 1700010I14 gene - - - - - 69380 1036 0.053333333 0.01 -2.415037499 Down 0.155656474 1700013G24Rik RIKEN cDNA 1700013G24 gene - - - - - 77592 3858 0.053333333 0.01 -2.415037499 Down 0.155656474 4931406H21Rik RIKEN cDNA 4931406H21 gene - - - - gi|187955228|gb|AAI47212.1|/3.62387e-61/RIKEN cDNA 4931406H21 gene [Mus musculus] 71664 1227 0.05 0.01 -2.321928095 Down 0.155656474 Mettl7b methyltransferase like 7B - GO:0044444//cytoplasmic part GO:0016741 GO:0008152//metabolic process gi|27229118|ref|NP_082129.2|/4.83432e-129/methyltransferase-like protein 7B precursor [Mus musculus] 58218 1048 0.01 0.053333333 2.415037499 Up 0.155656474 Trem3 triggering receptor expressed on myeloid cells 3 K14362|1|1e-42|176|myd:102758891|triggering receptor expressed on myeloid cells 1;K14364|5|5e-20|100|shr:100915356|trem-like transcript 2 protein - - - - 75453 1052 0.053333333 0.01 -2.415037499 Down 0.155656474 Ccdc7b coiled-coil domain containing 7B K20478|1|8e-08|60.5|acs:100562086|golgin subfamily B member 1 - - - gi|270265823|ref|NP_001161841.1|/0/uncharacterized protein LOC75453 isoform 1 [Mus musculus] 66930 2070 0.05 0.01 -2.321928095 Down 0.155656474 Fank1 fibronectin type 3 and ankyrin repeat domains 1 K15503|1|4e-27|125|aqu:100635111|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B GO:0031981//nuclear lumen - - gi|13385328|ref|NP_080126.1|/0/fibronectin type 3 and ankyrin repeat domains 1 protein [Mus musculus] 632708 1184 0.05 0.01 -2.321928095 Down 0.155656474 Dmrtc1b DMRT-like family C1b K19494|1|6e-132|473|mmu:632708|doublesex- and mab-3-related transcription factor 8 - - - gi|890769677|ref|NP_001297543.1|/6.84169e-147/DMRT-like family C1b isoform 1 [Mus musculus] 15434 2902 0.01 0.05 2.321928095 Up 0.155656474 Hoxd3 homeobox D3 K09303|1|0.0|758|mmu:15434|homeobox protein HoxA/B/D3 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0035270//endocrine system development;GO:0003002//regionalization;GO:0021563//glossopharyngeal nerve development;GO:0001501//skeletal system development;GO:0048562//embryonic organ morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0030182//neuron differentiation;GO:0031589//cell-substrate adhesion" gi|126517502|ref|NP_034598.2|/0/homeobox protein Hox-D3 [Mus musculus] 18315 1156 0.05 0.01 -2.321928095 Down 0.155656474 Olfr18 olfactory receptor 18 K04257|1|1e-170|601|mmu:18315|olfactory receptor - - - gi|126032327|ref|NP_666774.1|/8.78968e-170/olfactory receptor 18 [Mus musculus] 545662 1975 0.053333333 0.01 -2.415037499 Down 0.155656474 B020004J07Rik RIKEN cDNA B020004J07 gene K10308|1|2e-09|67.0|myd:102753733|F-box protein 31 - - - gi|85702111|ref|NP_001028962.1|/0/uncharacterized protein LOC545662 [Mus musculus] 100502653 1157 0.01 0.05 2.321928095 Up 0.155656474 C130060C02Rik RIKEN cDNA C130060C02 gene - - - - - 545384 1294 0.01 0.053333333 2.415037499 Up 0.155656474 BC094916 cDNA sequence BC094916 - - - GO:0035456//response to interferon-beta gi|160333317|ref|NP_001019892.2|/6.69978e-76/pyrin and HIN domain-containing protein 1-like [Mus musculus] 71836 2045 0.01 0.05 2.321928095 Up 0.155656474 Shcbp1l Shc SH2-domain binding protein 1-like - - - - gi|148707491|gb|EDL39438.1|/0/mCG22674 [Mus musculus] 17071 877 0.01 0.053333333 2.415037499 Up 0.155656474 Ly6f "lymphocyte antigen 6 complex, locus F" K06846|1|2e-46|188|mmu:110454|lymphocyte antigen 6 complex locus protein D/E/G6/H GO:0009986//cell surface;GO:0031224//intrinsic component of membrane - - gi|6678750|ref|NP_032556.1|/8.05832e-68/lymphocyte antigen 6F precursor [Mus musculus] 100504026 1082 0.01 0.05 2.321928095 Up 0.155656474 Gm16157 predicted gene 16157 - - - - "gi|148675221|gb|EDL07168.1|/5.33822e-41/mCG1028421, isoform CRA_b, partial [Mus musculus]" 66479 1128 0.01 0.05 2.321928095 Up 0.155656474 1700029F12Rik RIKEN cDNA 1700029F12 gene - - - - gi|124107621|ref|NP_001074246.1|/7.70244e-78/uncharacterized protein LOC66479 isoform 1 [Mus musculus] 100038516 1134 0.05 0.01 -2.321928095 Down 0.155656474 Gm10640 predicted gene 10640 - - - - - 257947 1130 0.01 0.05 2.321928095 Up 0.155656474 Olfr543 olfactory receptor 543 K04257|1|1e-177|624|mmu:257947|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|268607637|ref|NP_001011782.2|/1.22755e-176/olfactory receptor 543 [Mus musculus] 19218 2090 0.05 0.01 -2.321928095 Down 0.155656474 Ptger3 prostaglandin E receptor 3 (subtype EP3) K04260|1|0.0|688|mmu:19218|prostaglandin E receptor 3 GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0004955//prostaglandin receptor activity "GO:0001660//fever generation;GO:0015711//organic anion transport;GO:0035809;GO:0002237//response to molecule of bacterial origin;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0051480//regulation of cytosolic calcium ion concentration" gi|86355516|ref|NP_035326.2|/0/prostaglandin E2 receptor EP3 subtype [Mus musculus] 74156 3049 0.053333333 0.01 -2.415037499 Down 0.155656474 Acot12 acyl-CoA thioesterase 12 K01067|1|0.0|1051|mmu:74156|acetyl-CoA hydrolase [EC:3.1.2.1] GO:0044444//cytoplasmic part GO:0016289//CoA hydrolase activity;GO:0032550;GO:0052689//carboxylic ester hydrolase activity GO:0006637//acyl-CoA metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0044238//primary metabolic process gi|18482377|ref|NP_083066.1|/0/acyl-coenzyme A thioesterase 12 [Mus musculus] 18197 2168 0.01 0.05 2.321928095 Up 0.155656474 Nsg2 neuron specific gene family member 2 K15493|1|4e-21|105|cfa:491697|neuron-specific vesicular protein calcyon GO:0031224//intrinsic component of membrane;GO:0005771//multivesicular body;GO:0000139//Golgi membrane;GO:0012506//vesicle membrane;GO:0031224//intrinsic component of membrane;GO:0005771//multivesicular body;GO:0000139//Golgi membrane;GO:0012506//vesicle membrane;GO:0031224//intrinsic component of membrane;GO:0005771//multivesicular body;GO:0000139//Golgi membrane;GO:0012506//vesicle membrane GO:0030276//clathrin binding;GO:0001664//G-protein coupled receptor binding;GO:0030276//clathrin binding;GO:0001664//G-protein coupled receptor binding;GO:0030276//clathrin binding;GO:0001664//G-protein coupled receptor binding GO:0006901//vesicle coating;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006901//vesicle coating;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006901//vesicle coating;GO:0007186//G-protein coupled receptor signaling pathway gi|6679142|ref|NP_032767.1|/3.14261e-93/neuron-specific protein family member 2 [Mus musculus] 73904 1094 0.05 0.01 -2.321928095 Down 0.155656474 4833412C05Rik RIKEN cDNA 4833412C05 gene - - - - "gi|148675227|gb|EDL07174.1|/3.76498e-42/mCG49110, partial [Mus musculus]" 26366 1060 0.01 0.053333333 2.415037499 Up 0.155656474 Ceacam10 carcinoembryonic antigen-related cell adhesion molecule 10 K06499|1|1e-144|514|mmu:26366|carcinoembryonic antigen-related cell adhesion molecule - - - gi|229092064|ref|NP_031701.3|/9.45333e-144/carcinoembryonic antigen-related cell adhesion molecule 10 precursor [Mus musculus] 74548 2084 0.05 0.01 -2.321928095 Down 0.155656474 Gsdmc4 gasdermin C4 - GO:0044424 - - gi|254675345|ref|NP_083268.1|/0/gasdermin-C4 [Mus musculus] 71907 1694 0.01 0.053333333 2.415037499 Up 0.155656474 Serpina9 "serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9" "K04525|1|0.0|794|mmu:71907|serpin peptidase inhibitor, clade A" - - - gi|21313654|ref|NP_082273.1|/0/serpin A9 precursor [Mus musculus] 71637 1096 0.01 0.053333333 2.415037499 Up 0.155656474 4930413F20Rik RIKEN cDNA 4930413F20 gene - - - - - 68800 1123 0.053333333 0.01 -2.415037499 Down 0.155656474 Prr32 proline rich 32 - - - - gi|259906431|ref|NP_081117.1|/1.4443e-161/proline-rich protein 32 [Mus musculus] 100503185 1134 0.01 0.05 2.321928095 Up 0.155656474 Btbd8 BTB (POZ) domain containing 8 K10480|1|0.0|759|mmu:100503185|BTB/POZ domain-containing protein 8 GO:0031981//nuclear lumen - - gi|364502961|ref|NP_001242920.1|/0/BTB/POZ domain-containing protein 8 [Mus musculus] 66740 1095 0.01 0.05 2.321928095 Up 0.155656474 4931417E11Rik RIKEN cDNA 4931417E11 gene - GO:0044425 GO:0044389//ubiquitin-like protein ligase binding GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process gi|13385198|ref|NP_080013.1|/7.09659e-158/JNK1/MAPK8-associated membrane protein-like [Mus musculus] 74288 1060 0.01 0.053333333 2.415037499 Up 0.155656474 Spem1 sperm maturation 1 K07378|1|5e-22|107|umr:103660472|neuroligin GO:0031224//intrinsic component of membrane - GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|144227237|ref|NP_083131.1|/4.19392e-168/spermatid maturation protein 1 [Mus musculus] 625175 967 0.01 0.05 2.321928095 Up 0.155656474 1700028E10Rik RIKEN cDNA 1700028E10 gene - - - - - 14934 1827 0.01 0.053333333 2.415037499 Up 0.155656474 Gypa glycophorin A K06575|1|1e-89|333|mmu:14934|glycophorin GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0042802//identical protein binding GO:0006970//response to osmotic stress;GO:0007010//cytoskeleton organization gi|111185918|ref|NP_034499.3|/1.10336e-88/glycophorin-A [Mus musculus] 72677 1102 0.01 0.05 2.321928095 Up 0.155656474 2810049E08Rik RIKEN cDNA 2810049E08 gene - - - - - 217306 1963 0.01 0.05 2.321928095 Up 0.155656474 Cd300e CD300E molecule K06719|1|1e-79|300|mmu:217306|CD300A/C/E/H antigen GO:0031224//intrinsic component of membrane - - gi|25286711|ref|NP_742047.1|/1.12858e-78/CMRF35-like molecule 2 precursor [Mus musculus] 329244 1066 0.053333333 0.01 -2.415037499 Down 0.155656474 Il19 interleukin 19 K05444|1|1e-96|355|mmu:329244|interleukin 19/20/24 GO:0044421 - GO:0032635//interleukin-6 production;GO:0012502//induction of programmed cell death;GO:0044237//cellular metabolic process gi|568909309|ref|XP_006529768.1|/9.67709e-96/PREDICTED: interleukin-19 isoform X2 [Mus musculus] 71166 1127 0.05 0.01 -2.321928095 Down 0.155656474 4933424G06Rik RIKEN cDNA 4933424G06 gene - - - - - 17292 1098 0.053333333 0.01 -2.415037499 Down 0.155656474 Mesp1 mesoderm posterior 1 K09076|1|7e-121|436|mmu:17292|mesoderm posterior GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0005515//protein binding GO:0007509//mesoderm migration involved in gastrulation;GO:0003308//negative regulation of Wnt signaling pathway involved in heart development;GO:0003158//endothelium development;GO:0007501//mesodermal cell fate specification;GO:0001709//cell fate determination;GO:0003163//sinoatrial node development;GO:0003207//cardiac chamber formation;GO:0035051//cardiocyte differentiation;GO:0003137;GO:0045597//positive regulation of cell differentiation;GO:0007399//nervous system development;GO:0051146//striated muscle cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0003143//embryonic heart tube morphogenesis;GO:0003260//cardioblast migration;GO:0001714//endodermal cell fate specification gi|254588104|ref|NP_032614.2|/5.92624e-120/mesoderm posterior protein 1 [Mus musculus] 626834 1033 0.01 0.053333333 2.415037499 Up 0.155656474 Klk13 kallikrein related-peptidase 13 K09463|1|1e-167|591|mmu:626834|kallikrein 13 [EC:3.4.21.119] "GO:0044421;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0004175//endopeptidase activity GO:0051604//protein maturation gi|110681722|ref|NP_001034131.2|/1.00108e-166/kallikrein-13 precursor [Mus musculus] 545486 2004 0.053333333 0.01 -2.415037499 Down 0.155656474 Tubb1 "tubulin, beta 1 class VI" K07375|1|0.0|846|mmu:545486|tubulin beta GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005198//structural molecule activity GO:0009154//purine ribonucleotide catabolic process;GO:0044763;GO:0043623//cellular protein complex assembly gi|124430500|ref|NP_001074440.1|/0/tubulin beta-1 chain [Mus musculus] 101056149 1091 0.01 0.053333333 2.415037499 Up 0.155656474 Gm15908 predicted gene 15908 - - - - - 231290 2085 0.05 0.01 -2.321928095 Down 0.155656474 Slc10a4 "solute carrier family 10 (sodium/bile acid cotransporter family), member 4" "K14344|1|0.0|693|mmu:231290|solute carrier family 10 (sodium/bile acid cotransporter), member 4" GO:0031224//intrinsic component of membrane GO:0005343//organic acid:sodium symporter activity GO:0030001//metal ion transport gi|87044892|ref|NP_775579.2|/0/sodium/bile acid cotransporter 4 [Mus musculus] 102570 2021 0.053333333 0.01 -2.415037499 Down 0.155656474 Slc22a13 "solute carrier family 22 (organic cation transporter), member 13" "K08209|1|0.0|1069|mmu:102570|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 13" GO:0031224//intrinsic component of membrane GO:0005215//transporter activity - gi|225690546|ref|NP_598741.2|/0/solute carrier family 22 member 13 [Mus musculus] 17232 2000 0.053333333 0.01 -2.415037499 Down 0.155656474 Mcpt9 mast cell protease 9 K01329|1|2e-88|329|cge:100756053|chymase [EC:3.4.21.39];K08661|2|4e-88|328|mmu:17224|mast cell peptidase 1 [EC:3.4.21.-];K08662|4|3e-86|322|rno:29266|mast cell peptidase 2 [EC:3.4.21.-] GO:0044464 GO:0005539//glycosaminoglycan binding;GO:0033218//amide binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|157042790|ref|NP_034912.3|/6.25017e-133/mast cell protease 9 precursor [Mus musculus] 382035 1144 0.053333333 0.01 -2.415037499 Down 0.155656474 Pabpn1l poly(A)binding protein nuclear 1-like K14396|1|1e-147|525|mmu:382035|polyadenylate-binding protein 2 GO:0044424 GO:0036094//small molecule binding;GO:0003676//nucleic acid binding - gi|55925591|ref|NP_001007463.1|/1.02385e-146/embryonic polyadenylate-binding protein 2 [Mus musculus] 14599 903 0.01 0.053333333 2.415037499 Up 0.155656474 Gh growth hormone K05438|1|2e-109|397|mmu:14599|growth hormone - - - - 105245869 1150 0.05 0.01 -2.321928095 Down 0.155656474 LOC105245869 uncharacterized LOC105245869 - - - - - 67745 883 0.01 0.053333333 2.415037499 Up 0.155656474 4930583K01Rik RIKEN cDNA 4930583K01 gene - - - - - 67868 897 0.01 0.053333333 2.415037499 Up 0.155656474 Cela3b "chymotrypsin-like elastase family, member 3B" K01345|1|4e-156|552|mmu:67868|pancreatic endopeptidase E [EC:3.4.21.70] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process "gi|755475803|ref|XP_011250229.1|/3.09458e-155/PREDICTED: LOW QUALITY PROTEIN: chymotrypsin-like elastase family member 3B isoform X1, partial [Mus musculus]" 18159 1042 0.053333333 0.01 -2.415037499 Down 0.155656474 Nppc natriuretic peptide type C K12336|1|1e-38|162|mmu:18159|natriuretic peptide C GO:0044421 GO:0051427//hormone receptor binding;GO:0042802//identical protein binding;GO:0005179//hormone activity GO:0042127//regulation of cell proliferation;GO:0001649//osteoblast differentiation;GO:0006259//DNA metabolic process;GO:0042311//vasodilation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0003413//chondrocyte differentiation involved in endochondral bone morphogenesis;GO:0097305//response to alcohol;GO:0006182//cGMP biosynthetic process;GO:0003417//growth plate cartilage development;GO:0006950//response to stress;GO:0035264//multicellular organism growth gi|6754880|ref|NP_035063.1|/1.15694e-37/C-type natriuretic peptide preproprotein [Mus musculus] 67524 1069 0.01 0.053333333 2.415037499 Up 0.155656474 1700095A21Rik RIKEN cDNA 1700095A21 gene - - - - - 546644 922 0.01 0.053333333 2.415037499 Up 0.155656474 Ly6g "lymphocyte antigen 6 complex, locus G" K06846|1|2e-61|238|mmu:546644|lymphocyte antigen 6 complex locus protein D/E/G6/H GO:0009986//cell surface;GO:0031224//intrinsic component of membrane - - gi|882939087|ref|NP_001297367.1|/1.76195e-60/lymphocyte antigen 6G precursor [Mus musculus] 11801 2037 0.01 0.05 2.321928095 Up 0.155656474 Cd5l CD5 antigen-like K13912|1|3e-89|332|cmy:102947203|deleted in malignant brain tumors 1 protein GO:0044421 - GO:0006952//defense response;GO:0012501//programmed cell death gi|160358823|ref|NP_033820.2|/0/CD5 antigen-like precursor [Mus musculus] 240095 1170 0.05 0.01 -2.321928095 Down 0.155656474 H2-M5 "histocompatibility 2, M region locus 5" "K06751|1|0.0|680|mmu:240095|major histocompatibility complex, class I" GO:0042611 - GO:0019882//antigen processing and presentation "gi|169234920|ref|NP_001108547.1|/0/histocompatibility 2, M region locus 5 precursor [Mus musculus]" 24108 947 0.01 0.05 2.321928095 Up 0.155656474 Ubd ubiquitin D K12157|1|1e-79|298|mmu:24108|ubiquitin D GO:0016234//inclusion body;GO:0043231//intracellular membrane-bounded organelle GO:0032403//protein complex binding GO:0000236;GO:0006915//apoptotic process;GO:0034097//response to cytokine;GO:0070841;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0032446//protein modification by small protein conjugation;GO:0009719;GO:0001773//myeloid dendritic cell activation;GO:0019941//modification-dependent protein catabolic process gi|12963519|ref|NP_075626.1|/8.86974e-79/ubiquitin D [Mus musculus] 77288 2148 0.05 0.01 -2.321928095 Down 0.155656474 9430021M05Rik RIKEN cDNA 9430021M05 gene - - - - gi|26387912|dbj|BAC25632.1|/5.04276e-19/unnamed protein product [Mus musculus] 790909 1179 0.05 0.01 -2.321928095 Down 0.155656474 Gm11186 predicted gene 11186 - - - - "gi|148701661|gb|EDL33608.1|/1.48826e-63/mCG145519, partial [Mus musculus]" 320722 2296 0.05 0.01 -2.321928095 Down 0.155656474 A330050F15Rik A kinase (PRKA) anchor inhibitor 1 - - - - gi|223633923|ref|NP_001138664.1|/1.81586e-30/A-kinase anchor protein C18orf42 homolg [Mus musculus] 237320 2243 0.05 0.01 -2.321928095 Down 0.155656474 Aldh8a1 "aldehyde dehydrogenase 8 family, member A1" K00149|1|4e-89|332|nve:NEMVE_v1g192075|aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3] GO:0044424 "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor" GO:0002138//retinoic acid biosynthetic process gi|30520135|ref|NP_848828.1|/0/aldehyde dehydrogenase family 8 member A1 [Mus musculus] 227885 2163 0.05 0.01 -2.321928095 Down 0.155656474 Gm13498 "heat shock protein 90 alpha (cytosolic), class B member 1 pseudogene" K04079|1|0.0|341|tad:TRIADDRAFT_57068|molecular chaperone HtpG - GO:0005488//binding - gi|196006622|ref|XP_002113177.1|/0/Hsp90 [Trichoplax adhaerens] 12776 1156 0.05 0.01 -2.321928095 Down 0.155656474 Ccr8 chemokine (C-C motif) receptor 8 K04183|1|0.0|654|mmu:12776|C-C chemokine receptor type 8 - - - - 109901 1124 0.05 0.01 -2.321928095 Down 0.155656474 Cela1 "chymotrypsin-like elastase family, member 1" K01326|1|1e-142|508|mmu:109901|pancreatic elastase I [EC:3.4.21.36] - GO:0043169//cation binding;GO:0004175//endopeptidase activity GO:0006952//defense response;GO:0040007//growth;GO:0031016//pancreas development;GO:0009887//organ morphogenesis;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0030154//cell differentiation;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter gi|165932341|ref|NP_291090.2|/9.73286e-142/chymotrypsin-like elastase family member 1 precursor [Mus musculus] 208760 1085 0.053333333 0.01 -2.415037499 Down 0.155656474 Aqp12 aquaporin 12 K09871|1|8e-136|485|mmu:208760|aquaporin-12 GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0051234//establishment of localization gi|29243944|ref|NP_808255.1|/6.40492e-135/aquaporin-12 isoform 1 precursor [Mus musculus] 14598 2141 0.01 0.05 2.321928095 Up 0.155656474 Ggt1 gamma-glutamyltransferase 1 K18592|1|0.0|1085|mmu:14598|gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14] GO:0016021//integral component of membrane;GO:0044421;GO:0016021//integral component of membrane;GO:0044421 "GO:0016755//transferase activity, transferring amino-acyl groups;GO:0016755//transferase activity, transferring amino-acyl groups" GO:0030324//lung development;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0009612//response to mechanical stimulus;GO:0043627//response to estrogen;GO:0034097//response to cytokine;GO:0048232//male gamete generation;GO:0006954//inflammatory response;GO:0006749//glutathione metabolic process;GO:0000097//sulfur amino acid biosynthetic process;GO:0002237//response to molecule of bacterial origin;GO:0006979//response to oxidative stress;GO:0030324//lung development;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0009612//response to mechanical stimulus;GO:0043627//response to estrogen;GO:0034097//response to cytokine;GO:0048232//male gamete generation;GO:0006954//inflammatory response;GO:0006749//glutathione metabolic process;GO:0000097//sulfur amino acid biosynthetic process;GO:0002237//response to molecule of bacterial origin;GO:0006979//response to oxidative stress gi|6679995|ref|NP_032142.1|/0/gamma-glutamyltranspeptidase 1 precursor [Mus musculus] 75647 1154 0.01 0.05 2.321928095 Up 0.155656474 Ssmem1 serine-rich single-pass membrane protein 1 - - - - gi|21312998|ref|NP_083649.1|/3.72045e-128/serine-rich single-pass membrane protein 1 isoform b [Mus musculus] 259116 957 0.01 0.05 2.321928095 Up 0.155656474 Olfr559 olfactory receptor 559 K04257|1|2e-155|550|mmu:259116|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|22128741|ref|NP_667323.1|/1.71591e-154/olfactory receptor 559 [Mus musculus] 11529 2079 0.05 0.01 -2.321928095 Down 0.155656474 Adh7 "alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide" K13951|1|0.0|688|mmu:11529|alcohol dehydrogenase 1/7 [EC:1.1.1.1] GO:0031981//nuclear lumen GO:0005501//retinoid binding;GO:0043168//anion binding;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0016623;GO:0004022//alcohol dehydrogenase (NAD) activity;GO:0005102//receptor binding;GO:0000166//nucleotide binding GO:0051707//response to other organism;GO:0097305//response to alcohol;GO:0009968//negative regulation of signal transduction;GO:0001523//retinoid metabolic process;GO:0006067//ethanol metabolic process;GO:0019395//fatty acid oxidation gi|672044175|ref|XP_008759715.1|/0/PREDICTED: alcohol dehydrogenase class 4 mu/sigma chain isoform X1 [Rattus norvegicus] 76601 1129 0.01 0.05 2.321928095 Up 0.155656474 1700041M19Rik RIKEN cDNA 1700041M19 gene - - - - - 665635 1093 0.053333333 0.01 -2.415037499 Down 0.155656474 Gm14486 predicted gene 14486 - - - - - 69032 1057 0.053333333 0.01 -2.415037499 Down 0.155656474 Lyzl4 lysozyme-like 4 K01185|1|1e-27|125|mmu:69444|lysozyme [EC:3.2.1.17];K13915|5|2e-26|122|gja:107106129|lysozyme C [EC:3.2.1.17] - - - - 23993 1923 0.053333333 0.01 -2.415037499 Down 0.155656474 Klk7 "kallikrein related-peptidase 7 (chymotryptic, stratum corneum)" K08668|1|2e-140|501|mmu:23993|kallikrein 7 [EC:3.4.21.117] GO:0042599//lamellar body GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|18777665|ref|NP_036002.1|/1.90507e-139/kallikrein-7 precursor [Mus musculus] 242735 2327 0.01 0.05 2.321928095 Up 0.155656474 Lrrc38 leucine rich repeat containing 38 K06839|1|5e-26|122|cin:100184475|slit 2;K06838|5|4e-25|119|ola:101161946|slit 1 GO:0031224//intrinsic component of membrane GO:0015075//ion transmembrane transporter activity GO:0044765//single-organism transport "gi|125858045|gb|AAI29964.1|/0/Lrrc38 protein, partial [Mus musculus]" 71274 1153 0.05 0.01 -2.321928095 Down 0.155656474 4933433G15Rik RIKEN cDNA 4933433G15 gene - - - - - 100502723 1074 0.053333333 0.01 -2.415037499 Down 0.155656474 Tsga8 testis specific gene A8 - GO:0043231//intracellular membrane-bounded organelle - - "gi|229597173|gb|AAI39063.1|/9.2928e-54/Tsga8 protein, partial [Mus musculus]" 279706 1144 0.01 0.05 2.321928095 Up 0.155656474 Nup62cl nucleoporin 62 C-terminal like K14306|1|1e-90|335|ngi:103750040|nuclear pore complex protein Nup62 - - - "gi|71682487|gb|AAI00368.1|/1.38e-167/Nup62cl protein, partial [Mus musculus]" 67592 1959 0.053333333 0.01 -2.415037499 Down 0.155656474 4930524B15Rik RIKEN cDNA 4930524B15 gene - - - - gi|13385772|ref|NP_080538.1|/9.55401e-78/uncharacterized protein C5orf47 homolog [Mus musculus] 57756 1135 0.05 0.01 -2.321928095 Down 0.155656474 Fhl5 four and a half LIM domains 5 K14380|1|3e-127|457|lcm:102346315|four and a half LIM domains protein 2 GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0046914//transition metal ion binding GO:0006366//transcription from RNA polymerase II promoter gi|568927112|ref|XP_006538188.1|/0/PREDICTED: four and a half LIM domains protein 5 isoform X2 [Mus musculus] 74305 1132 0.01 0.05 2.321928095 Up 0.155656474 1700111N16Rik RIKEN cDNA 1700111N16 gene - - - - - 20186 1973 0.253333333 0.18 -0.493040011 Down 0.15563767 Nr1h4 "nuclear receptor subfamily 1, group H, member 4" K08537|1|0.0|998|mmu:20186|farnesoid X receptor GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin "GO:0046914//transition metal ion binding;GO:0033218//amide binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0042974//retinoic acid receptor binding;GO:0005496//steroid binding;GO:0043566//structure-specific DNA binding;GO:0046914//transition metal ion binding;GO:0033218//amide binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0042974//retinoic acid receptor binding;GO:0005496//steroid binding;GO:0043566//structure-specific DNA binding;GO:0046914//transition metal ion binding;GO:0033218//amide binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0042974//retinoic acid receptor binding;GO:0005496//steroid binding;GO:0043566//structure-specific DNA binding" GO:0008202//steroid metabolic process;GO:0009755//hormone-mediated signaling pathway;GO:0005975//carbohydrate metabolic process;GO:0001079//nitrogen catabolite regulation of transcription from RNA polymerase II promoter;GO:0001101//response to acid chemical;GO:0019627//urea metabolic process;GO:2000213//positive regulation of glutamate metabolic process;GO:0009755//hormone-mediated signaling pathway;GO:0019218//regulation of steroid metabolic process;GO:0005975//carbohydrate metabolic process;GO:0001079//nitrogen catabolite regulation of transcription from RNA polymerase II promoter;GO:0006699//bile acid biosynthetic process;GO:0001101//response to acid chemical;GO:0019627//urea metabolic process;GO:0009746;GO:2000213//positive regulation of glutamate metabolic process;GO:0044767//single-organism developmental process;GO:0002237//response to molecule of bacterial origin;GO:0008202//steroid metabolic process;GO:0009755//hormone-mediated signaling pathway;GO:0005975//carbohydrate metabolic process;GO:0001079//nitrogen catabolite regulation of transcription from RNA polymerase II promoter;GO:0001101//response to acid chemical;GO:0019627//urea metabolic process;GO:2000213//positive regulation of glutamate metabolic process gi|254911067|ref|NP_001157172.1|/0/bile acid receptor isoform 1 [Mus musculus] 225471 3264 0.183333333 0.256666667 0.485426827 Up 0.15563767 Ticam2 toll-like receptor adaptor molecule 2 K05409|1|9e-132|474|mmu:225471|TRIF-related adaptor molecule GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0005488//binding;GO:0060089 GO:0006952//defense response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0001816//cytokine production gi|27734184|ref|NP_775570.1|/8.00353e-131/TIR domain-containing adapter molecule 2 [Mus musculus] 71856 820 0.243333333 0.173333333 -0.489384841 Down 0.15563767 Wfdc3 WAP four-disulfide core domain 3 K12864|1|7e-15|83.2|clv:102090334|beta-catenin-like protein 1;K04931|2|2e-08|61.6|cfr:102517018|potassium voltage-gated channel delayed-rectifier subfamily S member 1;K17106|3|3e-08|61.2|aml:100480260|whey acidic protein - GO:0004866//endopeptidase inhibitor activity GO:0051346//negative regulation of hydrolase activity gi|568918436|ref|XP_006500254.1|/5.56101e-81/PREDICTED: WAP four-disulfide core domain protein 3 isoform X2 [Mus musculus] 68094 4717.74 39.71333333 38.58 -0.041770315 Down 0.15560006 Smarcc2 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2" K11649|1|0.0|1620|mmu:68094|SWI/SNF related-matrix-associated actin-dependent regulator of chromatin subfamily C GO:0031981//nuclear lumen;GO:0090544//BAF-type complex;GO:0090544//BAF-type complex;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0090544//BAF-type complex GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0005488//binding;GO:0003712//transcription cofactor activity;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0034728//nucleosome organization;GO:0016568//chromatin modification;GO:0016568//chromatin modification;GO:0048731//system development;GO:0034728//nucleosome organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0034728//nucleosome organization;GO:0016568//chromatin modification gi|166235123|ref|NP_001107568.1|/0/SWI/SNF complex subunit SMARCC2 isoform 2 [Mus musculus] 12294 3710 0.116666667 0.06 -0.959358016 Down 0.155524841 Cacna2d3 "calcium channel, voltage-dependent, alpha2/delta subunit 3" K04860|1|0.0|2099|mmu:12294|voltage-dependent calcium channel alpha-2/delta-3 GO:0034704//calcium channel complex GO:0005262//calcium channel activity;GO:0043169//cation binding;GO:0016247//channel regulator activity GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport gi|6753236|ref|NP_033915.1|/0/voltage-dependent calcium channel subunit alpha-2/delta-3 precursor [Mus musculus] 16668 1400 0.073333333 0.136666667 0.898120386 Up 0.155524841 Krt18 keratin 18 "K07604|1|0.0|665|xla:100037084|type I keratin, acidic" GO:0005813//centrosome;GO:0034399//nuclear periphery;GO:0044444//cytoplasmic part;GO:0005882//intermediate filament GO:0005515//protein binding GO:0006915//apoptotic process;GO:0043001//Golgi to plasma membrane protein transport;GO:0019221//cytokine-mediated signaling pathway;GO:0032502//developmental process gi|74198485|dbj|BAE39725.1|/0/unnamed protein product [Mus musculus] 99887 6224 0.07 0.133333333 0.929610672 Up 0.155524841 Tmem56 transmembrane protein 56 - GO:0031224//intrinsic component of membrane - - gi|30725869|ref|NP_849267.1|/1.8994e-155/transmembrane protein 56 [Mus musculus] 74482 865 0.063333333 0.123333333 0.961525852 Up 0.155524841 Ifitm7 interferon induced transmembrane protein 7 K06566|1|2e-52|207|mmu:74482|interferon induced transmembrane protein;K19831|2|5e-35|150|ngi:103751065|interferon induced transmembrane protein 1 GO:0005770//late endosome;GO:0031224//intrinsic component of membrane - GO:0046718//viral entry into host cell;GO:0001649//osteoblast differentiation;GO:0051707//response to other organism;GO:0019079//viral genome replication;GO:0008283//cell proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0002252;GO:0009952//anterior/posterior pattern specification;GO:0006952//defense response;GO:0016477//cell migration gi|148664968|gb|EDK97384.1|/9.20588e-69/mCG129814 [Mus musculus] 67503 890 0.12 0.063333333 -0.921997488 Down 0.155524841 1700001G17Rik RIKEN cDNA 1700001G17 gene - - - - gi|148682488|gb|EDL14435.1|/7.12979e-88/RIKEN cDNA 1700001G17 [Mus musculus] 14428 1957 0.13 0.066666667 -0.963474124 Down 0.155524841 Galr2 galanin receptor 2 K04231|1|0.0|647|mmu:14428|galanin receptor 2 GO:0031224//intrinsic component of membrane GO:0042277//peptide binding;GO:0008188//neuropeptide receptor activity GO:0030030//cell projection organization;GO:0006650//glycerophospholipid metabolic process;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0051480//regulation of cytosolic calcium ion concentration gi|161353471|ref|NP_034384.3|/0/galanin receptor type 2 [Mus musculus] 76497 1696 41.98666667 43.10333333 0.037868186 Up 0.155524841 Ppp1r11 "protein phosphatase 1, regulatory (inhibitor) subunit 11" K17553|1|6e-35|151|mmu:76497|protein phosphatase 1 regulatory subunit 11 GO:0044424 - GO:0044092//negative regulation of molecular function "gi|148691366|gb|EDL23313.1|/5.37875e-34/protein phosphatase 1, regulatory (inhibitor) subunit 11, isoform CRA_b [Mus musculus]" 110310 1602 0.066666667 0.123333333 0.887525271 Up 0.155524841 Krt7 keratin 7 "K07605|1|0.0|816|rno:300242|type II keratin, basic" GO:0031981//nuclear lumen;GO:0005882//intermediate filament GO:0005488//binding GO:0006412//translation;GO:0006259//DNA metabolic process;GO:0022403 "gi|148672099|gb|EDL04046.1|/0/keratin 7, isoform CRA_a, partial [Mus musculus]" 140488 4366 0.136666667 0.073333333 -0.898120386 Down 0.155524841 Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 K13197|1|0.0|998|mmu:140488|insulin-like growth factor 2 mRNA-binding protein 3 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0003729//mRNA binding;GO:0036094//small molecule binding GO:0006412//translation;GO:0001817//regulation of cytokine production;GO:0032502//developmental process gi|431908994|gb|ELK12585.1|/0/Insulin-like growth factor 2 mRNA-binding protein 3 [Pteropus alecto] 75693 892 0.12 0.063333333 -0.921997488 Down 0.155524841 3010001F23Rik RIKEN cDNA 3010001F23 gene - - - - - 171486 3568.12 35.62666667 36.75 0.044786743 Up 0.155524841 Cd99l2 CD99 antigen-like 2 K06520|1|2e-53|214|mcc:708996|CD99 antigen GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0022610 gi|21489963|ref|NP_612182.1|/1.12423e-85/CD99 antigen-like protein 2 isoform 2 precursor [Mus musculus] 20276 3515 0.333333333 0.416666667 0.321928095 Up 0.155459024 Scnn1a "sodium channel, nonvoltage-gated 1 alpha" K04824|1|0.0|1302|mmu:20276|amiloride-sensitive sodium channel subunit alpha GO:0044459;GO:0009986//cell surface;GO:0015629//actin cytoskeleton;GO:0034703//cation channel complex GO:0019904//protein domain specific binding;GO:0005272//sodium channel activity GO:0006814//sodium ion transport;GO:0007606//sensory perception of chemical stimulus;GO:0008015//blood circulation "gi|148667411|gb|EDK99827.1|/0/sodium channel, nonvoltage-gated, type I, alpha, isoform CRA_b, partial [Mus musculus]" 210757 1525 0.396666667 0.316666667 -0.324962155 Down 0.155459024 Themis thymocyte selection associated - GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0050851//antigen receptor-mediated signaling pathway;GO:0045058//T cell selection;GO:0050851//antigen receptor-mediated signaling pathway;GO:0045058//T cell selection gi|30520043|ref|NP_848781.1|/0/protein THEMIS isoform 1 [Mus musculus] 242502 1325 0.406666667 0.326666667 -0.316027493 Down 0.155459024 Gm428 predicted gene 428 - - - - gi|126032313|ref|NP_001075113.1|/0/uncharacterized protein LOC242502 [Mus musculus] 403187 2260 41.74666667 40.64 -0.038760606 Down 0.155449622 Opa3 optic atrophy 3 - GO:0043231//intracellular membrane-bounded organelle - GO:0006629//lipid metabolic process;GO:0050953//sensory perception of light stimulus;GO:0007005//mitochondrion organization gi|110625722|ref|NP_997408.2|/1.3073e-65/optic atrophy 3 protein homolog [Mus musculus] 54125 2943 1.31 1.443333333 0.139837712 Up 0.15544022 Polm "polymerase (DNA directed), mu" K03513|1|0.0|890|mmu:54125|DNA polymerase mu [EC:2.7.7.7] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0034061//DNA polymerase activity GO:0030098//lymphocyte differentiation;GO:0006259//DNA metabolic process;GO:0002566//somatic diversification of immune receptors via somatic mutation;GO:0033554//cellular response to stress gi|226423875|ref|NP_059097.2|/0/DNA-directed DNA/RNA polymerase mu [Mus musculus] 22724 3704 13.59333333 14.04 0.046643661 Up 0.15544022 Zbtb7b zinc finger and BTB domain containing 7B K10494|1|0.0|831|mmu:22724|zinc finger and BTB domain-containing protein 7 - - - - 268741 4458 12.34333333 11.89333333 -0.053578934 Down 0.15544022 Tox4 TOX high mobility group box family member 4 K18808|1|8e-33|145|bfo:BRAFLDRAFT_68489|toll-like receptor 13;K05925|3|5e-12|77.0|pale:102884097|mRNA (2'-O-methyladenosine-N6-)-methyltransferase [EC:2.1.1.62] GO:0008287//protein serine/threonine phosphatase complex;GO:0044427;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding - gi|50510609|dbj|BAD32290.1|/0/mKIAA0737 protein [Mus musculus] 23805 9074 1.406666667 1.276666667 -0.139898607 Down 0.15544022 Apc2 adenomatosis polyposis coli 2 K02085|1|0.0|3631|mmu:23805|adenomatosis polyposis coli protein GO:0043231//intracellular membrane-bounded organelle;GO:0005874//microtubule;GO:0015629//actin cytoskeleton;GO:0044444//cytoplasmic part;GO:0030027//lamellipodium;GO:0019897//extrinsic component of plasma membrane GO:0005515//protein binding GO:0030178//negative regulation of Wnt signaling pathway;GO:0035411//catenin import into nucleus gi|568967556|ref|XP_006513707.1|/0/PREDICTED: adenomatous polyposis coli protein 2 isoform X2 [Mus musculus] 74268 1432 12.47333333 12.92333333 0.051131177 Up 0.15544022 Aven "apoptosis, caspase activation inhibitor" - GO:0044464;GO:0044464 - GO:0006915//apoptotic process;GO:0006915//apoptotic process gi|260099647|ref|NP_001159407.1|/4.72765e-109/cell death regulator Aven isoform 2 [Mus musculus] 54380 6715 5.37 5.123333333 -0.067839329 Down 0.155430817 Smarcal1 "SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1" K14440|1|0.0|1704|mmu:54380|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:3.6.4.12] GO:0043231//intracellular membrane-bounded organelle "GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled" GO:0006366//transcription from RNA polymerase II promoter;GO:0006259//DNA metabolic process;GO:0009154//purine ribonucleotide catabolic process;GO:0006325//chromatin organization "gi|148667867|gb|EDL00284.1|/0/Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1, isoform CRA_a, partial [Mus musculus]" 213019 1514 5.25 5.5 0.067114196 Up 0.155430817 Pdlim2 PDZ and LIM domain 2 K19867|1|7e-16|87.8|ola:101168991|LIM domain-binding protein 3 GO:0005924//cell-substrate adherens junction;GO:0032432//actin filament bundle;GO:0005924//cell-substrate adherens junction;GO:0032432//actin filament bundle GO:0051393//alpha-actinin binding;GO:0046914//transition metal ion binding;GO:0017022//myosin binding;GO:0051393//alpha-actinin binding;GO:0046914//transition metal ion binding;GO:0017022//myosin binding - gi|22122423|ref|NP_666090.1|/9.63097e-165/PDZ and LIM domain protein 2 [Mus musculus] 67736 2113.54 5.13 4.883333333 -0.071092567 Down 0.155430817 Ccdc130 coiled-coil domain containing 130 K13115|1|4e-103|378|mmu:67736|coiled-coil domain-containing protein 130 - - GO:0051707//response to other organism;GO:0051707//response to other organism gi|21312808|ref|NP_080626.1|/0/coiled-coil domain-containing protein 130 isoform 1 [Mus musculus] 19777 3459 5.223333333 4.97 -0.071724922 Down 0.155430817 Uri1 "URI1, prefoldin-like chaperone" K17560|1|0.0|865|mmu:19777|unconventional prefoldin RPB5 interactor 1 "GO:0042995//cell projection;GO:0016591//DNA-directed RNA polymerase II, holoenzyme" GO:0005515//protein binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0019212//phosphatase inhibitor activity GO:0070848//response to growth factor;GO:0006366//transcription from RNA polymerase II promoter;GO:0051707//response to other organism;GO:0010921//regulation of phosphatase activity;GO:0044267//cellular protein metabolic process;GO:0006915//apoptotic process;GO:0016049//cell growth;GO:0032870//cellular response to hormone stimulus gi|254675261|ref|NP_035404.4|/0/unconventional prefoldin RPB5 interactor [Mus musculus] 71883 1712 39.75333333 40.85333333 0.039377961 Up 0.155393208 Coq2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase K06125|1|0.0|645|mmu:71883|4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] - - - - 382062 1307 0.963333333 1.08 0.16492432 Up 0.15524277 AB124611 cDNA sequence AB124611 - GO:0016020//membrane;GO:0031224//intrinsic component of membrane - - "gi|148693253|gb|EDL25200.1|/4.07395e-113/cDNA sequence AB124611, partial [Mus musculus]" 58994 5148 1.006666667 1.126666667 0.162474697 Up 0.15524277 Smpd3 "sphingomyelin phosphodiesterase 3, neutral" K12352|1|0.0|1270|mmu:58994|sphingomyelin phosphodiesterase 3 [EC:3.1.4.12] GO:0031985//Golgi cisterna;GO:0012505//endomembrane system;GO:0016020//membrane GO:0043169//cation binding;GO:0004620//phospholipase activity GO:0050896//response to stimulus;GO:0006644//phospholipid metabolic process;GO:0006643//membrane lipid metabolic process;GO:0002790//peptide secretion;GO:0007154//cell communication;GO:0032502//developmental process gi|10946902|ref|NP_067466.1|/0/sphingomyelin phosphodiesterase 3 [Mus musculus] 217648 1491 1.026666667 1.15 0.163666011 Up 0.15524277 Gm527 predicted gene 527 - - - - gi|71037371|ref|NP_001020776.1|/0/uncharacterized protein C14orf28 homolog [Mus musculus] 233067 2861 1.023333333 1.143333333 0.159969921 Up 0.15524277 Lrfn3 leucine rich repeat and fibronectin type III domain containing 3 K16356|1|0.0|1039|mmu:233067|leucine-rich repeat and fibronectin type-III domain-containing protein 3 GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0097060//synaptic membrane - GO:0022610 gi|30425224|ref|NP_780687.1|/0/leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor [Mus musculus] 230603 2343 1.043333333 1.166666667 0.161192265 Up 0.15524277 Ttc39a tetratricopeptide repeat domain 39A K02741|1|2e-12|77.0|cmy:102942434|20S proteasome subunit beta 9 [EC:3.4.25.1] - - - gi|225543132|ref|NP_001139420.1|/0/tetratricopeptide repeat protein 39A isoform 1 [Mus musculus] 238386 4325 1.163333333 1.043333333 -0.157064379 Down 0.15524277 Btbd7 BTB (POZ) domain containing 7 K10479|1|0.0|2057|mmu:238386|BTB/POZ domain-containing protein 7 - - - gi|31044481|ref|NP_766394.2|/0/BTB/POZ domain-containing protein 7 [Mus musculus] 223642 3338 8.056666667 7.736666667 -0.05847095 Down 0.155195758 Zc3h3 zinc finger CCCH type containing 3 K06093|1|3e-44|183|hmg:100206476|partitioning defective protein 6;K14404|2|1e-19|102|ola:101173062|cleavage and polyadenylation specificity factor subunit 4 GO:0005849//mRNA cleavage factor complex GO:0046914//transition metal ion binding;GO:0046332//SMAD binding GO:0031124//mRNA 3'-end processing;GO:0032924//activin receptor signaling pathway;GO:0006406//mRNA export from nucleus gi|26006471|ref|NP_742119.1|/0/zinc finger CCCH domain-containing protein 3 [Mus musculus] 11765 6882.05 7.056666667 7.373333333 0.063330116 Up 0.155195758 Ap1g1 "adaptor protein complex AP-1, gamma 1 subunit" K12391|1|0.0|1448|mmu:11765|AP-1 complex subunit gamma-1 GO:0005764//lysosome;GO:0005856//cytoskeleton;GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0005768//endosome;GO:0012506//vesicle membrane;GO:0005802//trans-Golgi network;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton;GO:0005768//endosome;GO:0030135//coated vesicle;GO:0005794//Golgi apparatus;GO:0030119//AP-type membrane coat adaptor complex GO:0008092//cytoskeletal protein binding;GO:0022892//substrate-specific transporter activity;GO:0008092//cytoskeletal protein binding;GO:0022892//substrate-specific transporter activity GO:0002478;GO:0044764;GO:0048193//Golgi vesicle transport;GO:0050688//regulation of defense response to virus;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0015031//protein transport gi|667751602|ref|NP_001288140.1|/0/AP-1 complex subunit gamma-1 isoform 2 [Mus musculus] 66101 752.69 8.246666667 7.93 -0.056490229 Down 0.155195758 Ppih peptidyl prolyl isomerase H K09567|1|8e-101|368|pale:102883518|peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8] GO:0030532//small nuclear ribonucleoprotein complex;GO:0016604//nuclear body;GO:0030532//small nuclear ribonucleoprotein complex;GO:0016604//nuclear body;GO:0030532//small nuclear ribonucleoprotein complex;GO:0016604//nuclear body GO:0008144//drug binding;GO:0016859//cis-trans isomerase activity;GO:0008144//drug binding;GO:0016859//cis-trans isomerase activity;GO:0008144//drug binding;GO:0016859//cis-trans isomerase activity GO:0019079//viral genome replication;GO:0018208//peptidyl-proline modification;GO:0000377;GO:0065003;GO:0019079//viral genome replication;GO:0018208//peptidyl-proline modification;GO:0000377;GO:0065003;GO:0019079//viral genome replication;GO:0018208//peptidyl-proline modification;GO:0000377;GO:0065003 gi|158631196|ref|NP_001103600.1|/4.01532e-106/peptidyl-prolyl cis-trans isomerase H isoform 2 [Mus musculus] 219257 5237 0.14 0.076666667 -0.868755467 Down 0.155195758 Pcdh20 protocadherin 20 K16498|1|0.0|1730|mmu:219257|protocadherin delta 1 - - - gi|260763990|ref|NP_848800.3|/0/protocadherin-20 precursor [Mus musculus] 14042 3478 8.263333333 8.586666667 0.055374322 Up 0.155195758 Ext1 exostoses (multiple) 1 K02366|1|0.0|1477|rno:299907|glucuronyl/N-acetylglucosaminyl transferase EXT1 [EC:2.4.1.224 2.4.1.225] GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0008375//acetylglucosaminyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding GO:0009888//tissue development;GO:0006023;GO:0048706//embryonic skeletal system development;GO:0007154//cell communication;GO:0000271//polysaccharide biosynthetic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0006935//chemotaxis;GO:0006464//cellular protein modification process;GO:0021988//olfactory lobe development;GO:0048598//embryonic morphogenesis gi|112807209|ref|NP_034292.2|/0/exostosin-1 [Mus musculus] 12054 1678 34.22 35.29 0.04441967 Up 0.155139343 Bcl7b B cell CLL/lymphoma 7B - - - - - 54387 6400 3.853333333 3.643333333 -0.080847997 Down 0.155092331 Mcm3ap minichromosome maintenance complex component 3 associated protein K16734|1|7e-46|189|sko:102800747|SAC3 domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - - gi|28972283|dbj|BAC65595.1|/0/mKIAA0572 protein [Mus musculus] 67019 1703 3.566666667 3.776666667 0.082537065 Up 0.155092331 Actr6 ARP6 actin-related protein 6 K11662|1|0.0|811|mmu:67019|actin-related protein 6 GO:0043232 - - gi|21313172|ref|NP_080190.1|/0/actin-related protein 6 [Mus musculus] 11766 2611 3.67 3.463333333 -0.083618815 Down 0.155092331 Ap1g2 "adaptor protein complex AP-1, gamma 2 subunit" K12391|1|0.0|1419|mmu:11766|AP-1 complex subunit gamma-1 "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0030119//AP-type membrane coat adaptor complex" GO:0022892//substrate-specific transporter activity;GO:0022892//substrate-specific transporter activity GO:0015031//protein transport;GO:0015031//protein transport "gi|148704358|gb|EDL36305.1|/0/adaptor protein complex AP-1, gamma 2 subunit, isoform CRA_a [Mus musculus]" 320939 5694 3.566666667 3.773333333 0.081263162 Up 0.155092331 5930403L14Rik RIKEN cDNA 5930403L14 gene "K19720|1|8e-06|56.6|rro:104664580|collagen, type III, alpha" - - - gi|74206245|dbj|BAE24883.1|/3.83775e-54/unnamed protein product [Mus musculus] 70584 2898 3.68 3.89 0.080064389 Up 0.155092331 Pak4 p21 protein (Cdc42/Rac)-activated kinase 4 K05734|1|0.0|1021|mmu:70584|p21-activated kinase 4 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004672//protein kinase activity GO:0012501//programmed cell death;GO:0006996//organelle organization;GO:0048870//cell motility;GO:0040007//growth;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007154//cell communication gi|60115461|dbj|BAC98108.2|/0/mKIAA1142 protein [Mus musculus] 69019 1022 38.96333333 40.02 0.038604061 Up 0.155045319 Spcs1 signal peptidase complex subunit 1 homolog (S. cerevisiae) K12946|1|2e-91|337|mmu:69019|signal peptidase complex subunit 1 [EC:3.4.-.-] - - - "gi|148692833|gb|EDL24780.1|/1.03446e-99/signal peptidase complex subunit 1 homolog (S. cerevisiae), isoform CRA_a, partial [Mus musculus]" 381582 1378 0.186666667 0.26 0.478047297 Up 0.155017112 Tmem240 transmembrane protein 240 - GO:0031224//intrinsic component of membrane - - gi|168480088|ref|NP_001094976.1|/7.75853e-102/transmembrane protein 240 [Mus musculus] 236266 10005 0.183333333 0.253333333 0.4665678 Up 0.155017112 Alms1 Alstrom syndrome 1 K16741|1|0.0|6025|mmu:236266|alstrom syndrome protein 1 - - - gi|153791438|ref|NP_660258.2|/0/Alstrom syndrome protein 1 homolog [Mus musculus] 13608 3697 0.236666667 0.17 -0.477321778 Down 0.155017112 Edar ectodysplasin-A receptor K05162|1|0.0|788|mmu:13608|tumor necrosis factor receptor superfamily member EDAR GO:0031224//intrinsic component of membrane;GO:0044464 GO:0005488//binding;GO:0038023//signaling receptor activity GO:0042476//odontogenesis;GO:0012501//programmed cell death;GO:0048869//cellular developmental process;GO:0007435//salivary gland morphogenesis;GO:0008544//epidermis development;GO:0042345//regulation of NF-kappaB import into nucleus gi|568966645|ref|XP_006513269.1|/0/PREDICTED: tumor necrosis factor receptor superfamily member EDAR isoform X3 [Mus musculus] 72181 3526 11.43 11.86666667 0.054089337 Up 0.154885479 Nsun4 "NOL1/NOP2/Sun domain family, member 4" K14835|1|4e-14|83.6|smm:Smp_005080.3|ribosomal RNA methyltransferase Nop2 [EC:2.1.1.-] - - - - 13481 877 11.67666667 12.11666667 0.053364376 Up 0.154885479 Dpm2 dolichol-phosphate (beta-D) mannosyltransferase 2 "K09658|1|6e-31|136|ocu:100356674|dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit" GO:0031224//intrinsic component of membrane;GO:0031501//mannosyltransferase complex;GO:0005789//endoplasmic reticulum membrane GO:0005488//binding;GO:0000030//mannosyltransferase activity GO:0010608//posttranscriptional regulation of gene expression;GO:0016093;GO:0006497//protein lipidation gi|655893499|ref|XP_008249241.1|/5.10628e-30/PREDICTED: dolichol phosphate-mannose biosynthesis regulatory protein [Oryctolagus cuniculus] 213573 1687 13.47 13.90666667 0.046026806 Up 0.154885479 Cracr2b calcium release activated channel regulator 2B K17199|1|2e-117|425|mmu:213573|Ras and EF-hand domain-containing protein GO:0044424 GO:0005488//binding GO:0051924//regulation of calcium ion transport "gi|29124550|gb|AAH48916.1|/3.85347e-141/Efcab4a protein, partial [Mus musculus]" 214895 2340.28 13.58666667 14.02666667 0.045980653 Up 0.154885479 Lman2l "lectin, mannose-binding 2-like" "K10083|1|5e-174|613|ngi:103738175|lectin, mannose-binding 2-like" GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0043169//cation binding GO:0045184//establishment of protein localization;GO:0045184//establishment of protein localization gi|74192251|dbj|BAE34318.1|/1.77565e-174/unnamed protein product [Mus musculus] 20901 2644 37.82333333 36.78 -0.040355032 Down 0.154847869 Strap serine/threonine kinase receptor associated protein K13137|1|0.0|652|mmu:20901|serine-threonine kinase receptor-associated protein GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex;GO:0016020//membrane "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005515//protein binding" GO:0006396//RNA processing;GO:0006796//phosphate-containing compound metabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter gi|160707896|ref|NP_035629.2|/0/serine-threonine kinase receptor-associated protein [Mus musculus] 75836 2019 0.27 0.196666667 -0.457206954 Down 0.15477265 Atxn7l1os2 "ataxin 7-like 1, opposite strand 2" K11318|1|5e-20|102|cge:100758796|ataxin-7 - - - - 70530 3001 0.193333333 0.266666667 0.4639471 Up 0.15477265 Lrfn2 leucine rich repeat and fibronectin type III domain containing 2 K16355|1|0.0|1300|mmu:70530|leucine-rich repeat and fibronectin type-III domain-containing protein 2 GO:0097060//synaptic membrane;GO:0031224//intrinsic component of membrane - - gi|28972684|dbj|BAC65758.1|/0/mKIAA1246 protein [Mus musculus] 68507 6067 0.553333333 0.466666667 -0.245756414 Down 0.154659822 Ppfia4 "protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4" K11446|1|7e-17|93.6|myd:102762785|histone demethylase JARID1 [EC:1.14.11.-];K16469|2|1e-15|89.7|dre:101885282|rootletin;K20478|4|1e-14|86.3|ola:101158337|golgin subfamily B member 1 - - - gi|221554491|ref|NP_001138327.1|/0/liprin-alpha-4 [Mus musculus] 320209 4167 0.536666667 0.45 -0.254101281 Down 0.154659822 Ddx11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 K11273|1|0.0|1608|mmu:320209|chromosome transmission fidelity protein 1 [EC:3.6.4.13] - - - - 58861 2802 0.556666667 0.466666667 -0.254421276 Down 0.154659822 Cysltr1 cysteinyl leukotriene receptor 1 K04322|1|0.0|716|mmu:58861|cysteinyl leukotriene receptor 1 GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0004930//G-protein coupled receptor activity;GO:0004930//G-protein coupled receptor activity GO:0006952//defense response;GO:0001525//angiogenesis;GO:0019229//regulation of vasoconstriction;GO:0042221//response to chemical;GO:0007166//cell surface receptor signaling pathway;GO:0070838//divalent metal ion transport;GO:0006952//defense response;GO:0001525//angiogenesis;GO:0019229//regulation of vasoconstriction;GO:0042221//response to chemical;GO:0007166//cell surface receptor signaling pathway;GO:0070838//divalent metal ion transport gi|31542449|ref|NP_067451.2|/0/cysteinyl leukotriene receptor 1 isoform a [Mus musculus] 269959 7285 0.576666667 0.483333333 -0.254719138 Down 0.154659822 Adamtsl3 ADAMTS-like 3 K08627|1|8e-89|332|xtr:100485801|a disintegrin and metalloproteinase with thrombospondin motifs 13 [EC:3.4.24.87] GO:0031012//extracellular matrix "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" - gi|298566265|ref|NP_001177303.1|/0/ADAMTS-like protein 3 [Mus musculus] 16594 3037.93 40.18666667 39.17 -0.036967788 Down 0.154650419 Klc2 kinesin light chain 2 K10407|1|0.0|806|mmu:16594|kinesin light chain GO:0005875//microtubule associated complex;GO:0044444//cytoplasmic part;GO:0042995//cell projection;GO:0005875//microtubule associated complex;GO:0044444//cytoplasmic part;GO:0042995//cell projection GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0010970//transport along microtubule;GO:0010970//transport along microtubule gi|672014573|ref|XP_008772980.1|/0/PREDICTED: kinesin light chain 2 isoform X1 [Rattus norvegicus] 104175 4092 38.40666667 39.42333333 0.037693008 Up 0.154650419 Sbk1 SH3-binding kinase 1 K08858|1|0.0|706|mmu:104175|serine/threonine-protein kinase SBK [EC:2.7.11.1] GO:0044424 GO:0004672//protein kinase activity;GO:0032550 GO:0007417//central nervous system development;GO:0006468//protein phosphorylation gi|21704180|ref|NP_663562.1|/0/serine/threonine-protein kinase SBK1 [Mus musculus] 14373 847 40.69666667 41.70333333 0.03525207 Up 0.154537591 G0s2 G0/G1 switch gene 2 - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding GO:0006629//lipid metabolic process;GO:0006915//apoptotic process gi|6679889|ref|NP_032085.1|/4.75929e-38/G0/G1 switch protein 2 [Mus musculus] 105968 583 0.97 0.856666667 -0.179250794 Down 0.154528188 AU021063 expressed sequence AU021063 - - - - - 19418 7595 0.9 0.793333333 -0.181997834 Down 0.154528188 Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 K12326|1|0.0|2259|mmu:19418|Ras-specific guanine nucleotide-releasing factor 2 GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0005515//protein binding GO:0007266//Rho protein signal transduction gi|7242199|ref|NP_033053.2|/0/ras-specific guanine nucleotide-releasing factor 2 [Mus musculus] 71960 6404.79 35.31666667 34.31666667 -0.041439758 Down 0.154443567 Myh14 "myosin, heavy polypeptide 14" K10352|1|0.0|2798|mmu:71960|myosin heavy chain GO:0043005//neuron projection;GO:0032432//actin filament bundle;GO:0043005//neuron projection;GO:0032432//actin filament bundle;GO:0043005//neuron projection;GO:0032432//actin filament bundle "GO:0032550;GO:0003779//actin binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003779//actin binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003779//actin binding;GO:0042623//ATPase activity, coupled" GO:0006928//movement of cell or subcellular component;GO:0009154//purine ribonucleotide catabolic process;GO:0006928//movement of cell or subcellular component;GO:0009154//purine ribonucleotide catabolic process;GO:0006928//movement of cell or subcellular component;GO:0009154//purine ribonucleotide catabolic process gi|408821455|ref|NP_001258469.1|/0/myosin-14 isoform 2 [Mus musculus] 20652 4785 0.733333333 0.633333333 -0.211504105 Down 0.154434165 Soat1 sterol O-acyltransferase 1 K00637|1|0.0|1045|mmu:20652|sterol O-acyltransferase [EC:2.3.1.26] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0032934//sterol binding;GO:0004772//sterol O-acyltransferase activity GO:0090077//foam cell differentiation;GO:0034434//sterol esterification;GO:0030301//cholesterol transport;GO:0016125//sterol metabolic process;GO:0019915//lipid storage;GO:0034377//plasma lipoprotein particle assembly;GO:0010560//positive regulation of glycoprotein biosynthetic process gi|84619697|ref|NP_033256.2|/0/sterol O-acyltransferase 1 [Mus musculus] 53381 964 11.96666667 11.54 -0.052378119 Down 0.15441536 Prdx4 peroxiredoxin 4 K03386|1|4e-150|533|mmu:53381|peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15] - - - - 60315 1480 11.68666667 11.26 -0.053656668 Down 0.15441536 Myg1 melanocyte proliferating gene 1 K08539|1|6e-82|307|gfr:102032089|vitamin D3 receptor GO:0043231//intracellular membrane-bounded organelle - - "gi|11096332|ref|NP_068359.1|/0/UPF0160 protein MYG1, mitochondrial precursor [Mus musculus]" 230793 6602 13.48 13.04666667 -0.047139241 Down 0.15441536 Ahdc1 "AT hook, DNA binding motif, containing 1" K06030|1|4e-38|164|shr:100928115|mitofusin [EC:3.6.5.-];K02350|2|5e-08|64.3|phi:102112724|DNA polymerase zeta [EC:2.7.7.7] - - - "gi|148698133|gb|EDL30080.1|/0/AT hook, DNA binding motif, containing 1, isoform CRA_b, partial [Mus musculus]" 22644 3296 6.803333333 7.11 0.063607783 Up 0.154396555 Rnf103 ring finger protein 103 K15695|1|0.0|1334|mmu:22644|E3 ubiquitin-protein ligase RNF103 [EC:2.3.2.27] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation;GO:0007399//nervous system development;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation;GO:0007399//nervous system development "gi|148666528|gb|EDK98944.1|/0/ring finger protein 103, isoform CRA_c, partial [Mus musculus]" 70239 2805 6.81 7.12 0.064222443 Up 0.154396555 Gtf3c5 "general transcription factor IIIC, polypeptide 5" K15202|1|0.0|959|mmu:70239|general transcription factor 3C polypeptide 5 (transcription factor C subunit 1) GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0007519//skeletal muscle tissue development;GO:0010467//gene expression;GO:0007519//skeletal muscle tissue development;GO:0010467//gene expression gi|594190933|ref|NP_001277413.1|/0/general transcription factor 3C polypeptide 5 isoform a [Mus musculus] 67180 2329 8.026666667 8.34 0.055246397 Up 0.154396555 Yipf5 "Yip1 domain family, member 5" K20363|1|1e-115|419|mmu:67180|protein transport protein YIP1 GO:0000139//Golgi membrane;GO:0044432;GO:0031224//intrinsic component of membrane;GO:0030133//transport vesicle - GO:0045184//establishment of protein localization;GO:0006888//ER to Golgi vesicle-mediated transport gi|12963631|ref|NP_075800.1|/1.2086e-114/protein YIPF5 [Mus musculus] 11639 4963.89 8.043333333 7.73 -0.057325096 Down 0.154396555 Ak4 adenylate kinase 4 K00939|1|2e-124|450|mmu:11639|adenylate kinase [EC:2.7.4.3] GO:0044429;GO:0044429;GO:0044429;GO:0044429 "GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019205//nucleobase-containing compound kinase activity;GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019205//nucleobase-containing compound kinase activity;GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019205//nucleobase-containing compound kinase activity;GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019205//nucleobase-containing compound kinase activity" GO:0007417//central nervous system development;GO:0016999//antibiotic metabolic process;GO:0042196;GO:0009150//purine ribonucleotide metabolic process;GO:0007417//central nervous system development;GO:0016999//antibiotic metabolic process;GO:0042196;GO:0009150//purine ribonucleotide metabolic process;GO:0007417//central nervous system development;GO:0016999//antibiotic metabolic process;GO:0042196;GO:0009150//purine ribonucleotide metabolic process;GO:0007417//central nervous system development;GO:0016999//antibiotic metabolic process;GO:0042196;GO:0009150//purine ribonucleotide metabolic process "gi|564351830|ref|XP_006238507.1|/1.83454e-140/PREDICTED: adenylate kinase 4, mitochondrial isoform X1 [Rattus norvegicus]" 12889 2217 0.2 0.273333333 0.450661409 Up 0.15437775 Cplx1 complexin 1 K15294|1|3e-31|139|aml:100481365|complexin-1/2 GO:0043005//neuron projection;GO:0044297//cell body;GO:0031201//SNARE complex GO:0005215//transporter activity;GO:0019905//syntaxin binding GO:0006887//exocytosis;GO:0030072//peptide hormone secretion gi|752420454|ref|XP_002924450.2|/2.27116e-30/PREDICTED: complexin-1 [Ailuropoda melanoleuca] 18738 3796 34.72 33.73333333 -0.041592064 Down 0.154358945 Pitpna "phosphatidylinositol transfer protein, alpha" - - - - - 56212 1264 31.13333333 32.10333333 0.044263053 Up 0.154199105 Rhog ras homolog family member G "K07863|1|3e-109|397|cfa:485217|Ras homolog gene family, member G" GO:0016020//membrane;GO:0044444//cytoplasmic part GO:0032550;GO:0017111//nucleoside-triphosphatase activity "GO:0007010//cytoskeleton organization;GO:0006351//transcription, DNA-templated;GO:0007599//hemostasis;GO:0051130//positive regulation of cellular component organization;GO:0008283//cell proliferation;GO:0006935//chemotaxis;GO:0001775//cell activation" gi|426367033|ref|XP_004050543.1|/4.81431e-111/PREDICTED: rho-related GTP-binding protein RhoG isoform 4 [Gorilla gorilla gorilla] 50771 5444 5.086666667 5.323333333 0.065609351 Up 0.1541803 Atp9b "ATPase, class II, type 9B" K01530|1|0.0|2102|mmu:50771|phospholipid-translocating ATPase [EC:3.6.3.1] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0032550;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0003824//catalytic activity;GO:0032550;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0003824//catalytic activity GO:0006811//ion transport;GO:0034067//protein localization to Golgi apparatus;GO:0006869//lipid transport;GO:0006811//ion transport;GO:0034067//protein localization to Golgi apparatus;GO:0006869//lipid transport gi|40807502|ref|NP_056620.2|/0/probable phospholipid-transporting ATPase IIB isoform 2 [Mus musculus] 664837 804 0.14 0.08 -0.807354922 Down 0.1541803 Gm7361 predicted gene 7361 - - - - gi|528078349|ref|NP_001268456.1|/2.25119e-111/spermatogenesis associated glutamate (E)-rich protein-like [Mus musculus] 654810 657 0.083333333 0.146666667 0.815575429 Up 0.1541803 Appbp2os "amyloid beta precursor protein (cytoplasmic tail) binding protein 2, opposite strand" - - - - - 13555 2715.28 4.946666667 5.183333333 0.067423488 Up 0.1541803 E2f1 E2F transcription factor 1 K17454|1|2e-169|598|mmu:13555|transcription factor E2F1 GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding GO:0070848//response to growth factor;GO:1901990//regulation of mitotic cell cycle phase transition;GO:0006974//cellular response to DNA damage stimulus;GO:0012501//programmed cell death;GO:0070542//response to fatty acid;GO:0043488//regulation of mRNA stability;GO:0008284//positive regulation of cell proliferation;GO:0007420//brain development;GO:0001666//response to hypoxia;GO:0048232//male gamete generation;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0070848//response to growth factor;GO:1901990//regulation of mitotic cell cycle phase transition;GO:0006974//cellular response to DNA damage stimulus;GO:0012501//programmed cell death;GO:0070542//response to fatty acid;GO:0043488//regulation of mRNA stability;GO:0008284//positive regulation of cell proliferation;GO:0007420//brain development;GO:0001666//response to hypoxia;GO:0048232//male gamete generation;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle gi|597955341|ref|NP_001278034.1|/0/transcription factor E2F1 isoform b precursor [Mus musculus] 17969 2722 4.89 5.13 0.069124361 Up 0.1541803 Ncf1 neutrophil cytosolic factor 1 K08011|1|0.0|778|mmu:17969|neutrophil cytosolic factor 1 GO:0043005//neuron projection;GO:0044297//cell body;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0005783//endoplasmic reticulum;GO:0005887//integral component of plasma membrane "GO:0005543//phospholipid binding;GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor;GO:0019904//protein domain specific binding;GO:0005543//phospholipid binding;GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor;GO:0019904//protein domain specific binding;GO:0005543//phospholipid binding;GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor;GO:0019904//protein domain specific binding" GO:0012501//programmed cell death;GO:0042743//hydrogen peroxide metabolic process;GO:0006605//protein targeting;GO:0050832//defense response to fungus;GO:0006690//icosanoid metabolic process;GO:0002252;GO:0001906//cell killing;GO:0006801//superoxide metabolic process;GO:0006939//smooth muscle contraction;GO:0050830//defense response to Gram-positive bacterium;GO:0012501//programmed cell death;GO:0042743//hydrogen peroxide metabolic process;GO:0006605//protein targeting;GO:0050832//defense response to fungus;GO:0006690//icosanoid metabolic process;GO:0002252;GO:0001906//cell killing;GO:0006801//superoxide metabolic process;GO:0006939//smooth muscle contraction;GO:0050830//defense response to Gram-positive bacterium;GO:0012501//programmed cell death;GO:0042743//hydrogen peroxide metabolic process;GO:0006605//protein targeting;GO:0050832//defense response to fungus;GO:0006690//icosanoid metabolic process;GO:0002252;GO:0001906//cell killing;GO:0006801//superoxide metabolic process;GO:0006939//smooth muscle contraction;GO:0050830//defense response to Gram-positive bacterium gi|74191435|dbj|BAE30297.1|/0/unnamed protein product [Mus musculus] 72065 3562 5.076666667 4.84 -0.068874488 Down 0.1541803 Rap2c "RAP2C, member of RAS oncogene family" K07839|1|7e-90|335|pale:102888447|Ras-related protein Rap-2C GO:0010008//endosome membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0001934//positive regulation of protein phosphorylation;GO:0007265//Ras protein signal transduction;GO:0045859//regulation of protein kinase activity;GO:0009154//purine ribonucleotide catabolic process;GO:0016477//cell migration gi|528759208|gb|EPY78867.1|/7.30552e-93/ras-related protein Rap-2c-like protein [Camelus ferus] 268595 5806 0.073333333 0.13 0.8259706 Up 0.1541803 D430019H16Rik RIKEN cDNA D430019H16 gene - - - - gi|913486512|ref|XP_013205341.1|/5.10454e-54/PREDICTED: uncharacterized protein C14orf132 homolog [Microtus ochrogaster] 102636620 1422 0.073333333 0.13 0.8259706 Up 0.1541803 Gm15326 predicted gene 15326 - - - - - 20844 3720 4.973333333 4.733333333 -0.071356606 Down 0.1541803 Stam signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 K04705|1|0.0|985|mmu:20844|signal transducing adaptor molecule GO:0043231//intracellular membrane-bounded organelle - GO:0015031//protein transport gi|6755668|ref|NP_035614.1|/0/signal transducing adapter molecule 1 [Mus musculus] 73877 3132 0.14 0.08 -0.807354922 Down 0.1541803 4930432J09Rik RIKEN cDNA 4930432J09 gene - - - - - 319922 3578 0.073333333 0.13 0.8259706 Up 0.1541803 Vwc2 von Willebrand factor C domain containing 2 K17280|1|4e-13|80.1|pss:102444146|chordin-like protein 2 GO:0005578//proteinaceous extracellular matrix;GO:0008328//ionotropic glutamate receptor complex - GO:0030509//BMP signaling pathway;GO:0010810//regulation of cell-substrate adhesion;GO:0030182//neuron differentiation gi|28892913|ref|NP_796007.1|/5.88117e-167/brorin precursor [Mus musculus] 238123 2997 5.436666667 5.193333333 -0.066061549 Down 0.1541803 Cog5 component of oligomeric golgi complex 5 K20292|1|0.0|1563|mmu:238123|conserved oligomeric Golgi complex subunit 5 - - - "gi|148704956|gb|EDL36903.1|/0/mCG22471, isoform CRA_a, partial [Mus musculus]" 67143 4440 5.22 4.983333333 -0.066938728 Down 0.1541803 Ikzf5 IKAROS family zinc finger 5 K09220|1|0.0|798|mmu:67143|IKAROS family zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|31982165|ref|NP_780324.2|/0/zinc finger protein Pegasus [Mus musculus] 21935 812 0.073333333 0.13 0.8259706 Up 0.1541803 Tnfrsf17 "tumor necrosis factor receptor superfamily, member 17" K05153|1|4e-106|386|mmu:21935|tumor necrosis factor receptor superfamily member 17 GO:0031224//intrinsic component of membrane - - gi|6755823|ref|NP_035738.1|/3.19738e-105/tumor necrosis factor receptor superfamily member 17 [Mus musculus] 109880 9728 1.856666667 2.01 0.114480675 Up 0.154105081 Braf Braf transforming gene K04365|1|0.0|1425|mmu:109880|B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] - GO:0043169//cation binding;GO:0004871//signal transducer activity;GO:0004672//protein kinase activity;GO:0032550 GO:0007165//signal transduction gi|153791904|ref|NP_647455.3|/0/serine/threonine-protein kinase B-raf [Mus musculus] 224090 4241 2.16 2.006666667 -0.106230326 Down 0.154105081 Tmem44 transmembrane protein 44 - - - - "gi|148665322|gb|EDK97738.1|/0/transmembrane protein 44, isoform CRA_j, partial [Mus musculus]" 20482 6734.19 1.966666667 2.116666667 0.106041637 Up 0.154105081 Skil SKI-like K18499|1|0.0|1238|mmu:20482|Ski-like protein - - - gi|84875520|ref|NP_001034179.1|/0/ski-like protein isoform b [Mus musculus] 14734 2272 1.966666667 2.116666667 0.106041637 Up 0.154105081 Gpc3 glypican 3 K08109|1|0.0|1090|mmu:14734|glypican 3 GO:0016021//integral component of membrane;GO:0000323//lytic vacuole;GO:0031225//anchored component of membrane;GO:0031012//extracellular matrix GO:0030414//peptidase inhibitor activity;GO:0043168//anion binding GO:0001656//metanephros development;GO:0072171;GO:0040007//growth;GO:0002573//myeloid leukocyte differentiation;GO:0001657//ureteric bud development;GO:0001568//blood vessel development;GO:0001503//ossification;GO:0030326//embryonic limb morphogenesis;GO:0008285//negative regulation of cell proliferation;GO:0051346//negative regulation of hydrolase activity;GO:0030178//negative regulation of Wnt signaling pathway;GO:0007224//smoothened signaling pathway;GO:0009798//axis specification;GO:0030323//respiratory tube development;GO:0006897//endocytosis;GO:2000052//positive regulation of non-canonical Wnt signaling pathway;GO:0010828//positive regulation of glucose transport;GO:0048754//branching morphogenesis of an epithelial tube;GO:0009896;GO:0030509//BMP signaling pathway gi|55249689|gb|AAH85756.1|/0/Glypican 3 [Rattus norvegicus] 100273 3202.55 35.83666667 36.79666667 0.03813863 Up 0.154067472 Osbpl9 oxysterol binding protein-like 9 K20465|1|0.0|1313|cge:100751414|oxysterol-binding protein-related protein 9/10/11 - GO:0008289//lipid binding;GO:0008289//lipid binding GO:0051234//establishment of localization;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0010876//lipid localization gi|625183995|ref|XP_003496539.2|/0/PREDICTED: oxysterol-binding protein-related protein 9 isoform X4 [Cricetulus griseus] 11632 1993.62 30.72666667 31.69 0.044536393 Up 0.154067472 Aip aryl-hydrocarbon receptor-interacting protein K17767|1|0.0|674|mmu:11632|AH receptor-interacting protein GO:0005829//cytosol;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0005829//cytosol;GO:0031981//nuclear lumen;GO:0016020//membrane "GO:0000989//transcription factor activity, transcription factor binding;GO:0019904//protein domain specific binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0019904//protein domain specific binding" GO:0006457//protein folding;GO:0006605//protein targeting;GO:0051342;GO:0006457//protein folding;GO:0006605//protein targeting;GO:0051342 gi|7709982|ref|NP_057875.1|/0/AH receptor-interacting protein [Mus musculus] 66308 2672 2.79 2.973333333 0.091816087 Up 0.153888826 Mplkip M-phase specific PLK1 intereacting protein - GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle - GO:0000087//mitotic M phase gi|13384898|ref|NP_079755.1|/3.79613e-59/M-phase-specific PLK1-interacting protein [Mus musculus] 22762 4974 3.006666667 2.823333333 -0.090765464 Down 0.153888826 Zfpm2 "zinc finger protein, multitype 2" K17442|1|0.0|2309|mmu:22762|zinc finger protein ZFPM2 GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0003676//nucleic acid binding GO:0051094//positive regulation of developmental process;GO:0007599//hemostasis;GO:0003215//cardiac right ventricle morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0051093//negative regulation of developmental process;GO:0006366//transcription from RNA polymerase II promoter;GO:0003183//mitral valve morphogenesis;GO:0003186//tricuspid valve morphogenesis;GO:0045444//fat cell differentiation;GO:0043009//chordate embryonic development;GO:0030323//respiratory tube development;GO:0008219//cell death;GO:0003281//ventricular septum development;GO:0003171//atrioventricular valve development;GO:0001570//vasculogenesis gi|6756071|ref|NP_035896.1|/0/zinc finger protein ZFPM2 [Mus musculus] 228071 8951 2.703333333 2.886666667 0.094665111 Up 0.153888826 Sestd1 SEC14 and spectrin domains 1 K12567|1|5e-96|357|crg:105342773|titin [EC:2.7.11.1];K08810|5|1e-58|233|xma:102222464|triple functional domain protein [EC:2.7.11.1] GO:0034703//cation channel complex GO:0043168//anion binding;GO:1901981//phosphatidylinositol phosphate binding - "gi|148695277|gb|EDL27224.1|/0/SEC14 and spectrin domains 1, isoform CRA_b, partial [Mus musculus]" 68526 4968.99 2.746666667 2.926666667 0.091576602 Up 0.153888826 Gpr155 G protein-coupled receptor 155 "K19475|1|4e-15|87.4|lcm:102354926|WAS/WASL-interacting protein;K20402|2|2e-07|62.0|aqu:100640629|DEP domain-containing mTOR-interacting protein;K12365|5|5e-07|60.5|lcm:102357864|phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein" - - - - 75415 4959 2.736666667 2.92 0.093548648 Up 0.153888826 Arhgap12 Rho GTPase activating protein 12 K10396|1|1e-80|305|mgp:100538629|kinesin family member 5;K01556|2|4e-79|300|xtr:100485536|kynureninase [EC:3.7.1.3];K20315|3|3e-35|154|xla:398972|Rho GTPase-activating protein 21/23 GO:0044464;GO:0044464 GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0008047//enzyme activator activity;GO:0008289//lipid binding GO:0007154//cell communication;GO:0007154//cell communication "gi|148691090|gb|EDL23037.1|/0/Rho GTPase activating protein 12, isoform CRA_b, partial [Mus musculus]" 50931 2671 1.05 1.166666667 0.152003093 Up 0.153879424 Il27ra "interleukin 27 receptor, alpha" K19598|1|0.0|1223|mmu:50931|interleukin 27 receptor alpha GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0004896//cytokine receptor activity GO:0042742//defense response to bacterium;GO:0001819//positive regulation of cytokine production;GO:0002828//regulation of type 2 immune response;GO:0045191//regulation of isotype switching gi|170932522|ref|NP_057880.2|/0/interleukin-27 receptor subunit alpha precursor [Mus musculus] 67557 2308 1.163333333 1.286666667 0.145373811 Up 0.153879424 Larp6 "La ribonucleoprotein domain family, member 6" K18733|1|0.0|873|mmu:67557|la-related protein 6 GO:0032991//macromolecular complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0036094//small molecule binding GO:0006412//translation gi|31981025|ref|NP_080511.2|/0/la-related protein 6 [Mus musculus] 100504029 956 1.053333333 1.17 0.151546472 Up 0.153879424 Gm16740 "predicted gene, 16740" - - - - "gi|148706840|gb|EDL38787.1|/1.96048e-49/mCG146332, partial [Mus musculus]" 54201 6893 2.34 2.176666667 -0.104388039 Down 0.153832412 Zfp316 zinc finger protein 316 K09228|1|0.0|1679|mmu:54201|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|255708390|ref|NP_059495.3|/0/zinc finger protein 316 [Mus musculus] 64453 4874 2.243333333 2.086666667 -0.104443848 Down 0.153832412 Zfp280b zinc finger protein 280B K09228|1|3e-13|81.3|lgi:LOTGIDRAFT_120297|KRAB domain-containing zinc finger protein - - - - 338467 4237 2.31 2.153333333 -0.101321187 Down 0.153832412 Morc3 microrchidia 3 K10421|1|1e-07|62.4|xma:102219107|CAP-Gly domain-containing linker protein 1;K20282|2|6e-07|60.1|gfr:102033042|GRIP and coiled-coil domain-containing protein 2;K16808|3|9e-07|59.3|xtr:100145664|nuclear mitotic apparatus protein 1;K20478|4|1e-06|58.9|dgr:Dgri_GH24649|golgin subfamily B member 1;K16536|5|1e-06|58.9|chx:100861101|protein HOOK3 - - - gi|50510377|dbj|BAD32174.1|/0/mKIAA0136 protein [Mus musculus] 66413 1313 33.25 34.19 0.040220082 Up 0.153832412 Psmd6 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 6" K03037|1|0.0|738|mmu:66413|26S proteasome regulatory subunit N7 GO:0031981//nuclear lumen;GO:0000502//proteasome complex;GO:0044444//cytoplasmic part GO:0017111//nucleoside-triphosphatase activity "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0006915//apoptotic process;GO:0044764;GO:0051320;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0009154//purine ribonucleotide catabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|46049022|ref|NP_079826.2|/0/26S proteasome non-ATPase regulatory subunit 6 [Mus musculus] 94279 3228 2.153333333 2.31 0.101321187 Up 0.153832412 Sfxn2 sideroflexin 2 K03351|1|3e-78|296|smm:Smp_136960|anaphase-promoting complex subunit 4;K02542|2|2e-10|70.9|pxy:105395647|DNA replication licensing factor MCM6 [EC:3.6.4.12] GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0015075//ion transmembrane transporter activity GO:0044763;GO:0055080//cation homeostasis;GO:0006811//ion transport gi|86439984|ref|NP_444426.3|/6.60307e-178/sideroflexin-2 [Mus musculus] 240066 5321 1.81 1.67 -0.116141595 Down 0.15382301 Zfp870 zinc finger protein 870 K09228|1|0.0|1170|mmu:240066|KRAB domain-containing zinc finger protein - - - gi|46402247|ref|NP_997128.1|/0/zinc finger protein 870 [Mus musculus] 68031 4053.73 11.51666667 11.94 0.052079627 Up 0.1537854 Rnf146 ring finger protein 146 K15700|1|6e-173|611|mmu:68031|E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0097367//carbohydrate derivative binding;GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination;GO:0030177//positive regulation of Wnt signaling pathway "gi|148672893|gb|EDL04840.1|/2.64336e-176/ring finger protein 146, isoform CRA_b, partial [Mus musculus]" 68215 1861 11.54333333 11.12 -0.053903099 Down 0.1537854 Fam98b "family with sequence similarity 98, member B" K15434|1|1e-165|585|mmu:68215|protein FAM98B GO:0043234//protein complex - - "gi|148695948|gb|EDL27895.1|/9.64919e-165/RIKEN cDNA 2610510H03, isoform CRA_a [Mus musculus]" 14182 4883.82 11.37 11.78666667 0.05192352 Up 0.1537854 Fgfr1 fibroblast growth factor receptor 1 K04362|1|0.0|1419|mcc:700126|fibroblast growth factor receptor 1 [EC:2.7.10.1] GO:0031224//intrinsic component of membrane;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005539//glycosaminoglycan binding;GO:0032550;GO:0042802//identical protein binding;GO:0019838//growth factor binding GO:0021700//developmental maturation;GO:0006915//apoptotic process;GO:0043405//regulation of MAP kinase activity;GO:0008284//positive regulation of cell proliferation;GO:0043009//chordate embryonic development;GO:0007435//salivary gland morphogenesis;GO:0050954//sensory perception of mechanical stimulus;GO:0010518//positive regulation of phospholipase activity;GO:0021761//limbic system development;GO:0051726//regulation of cell cycle;GO:0042471//ear morphogenesis;GO:0019233//sensory perception of pain;GO:0042491//auditory receptor cell differentiation;GO:0001649//osteoblast differentiation;GO:0010975//regulation of neuron projection development;GO:0003156//regulation of organ formation;GO:0021953//central nervous system neuron differentiation;GO:0001570//vasculogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0035108//limb morphogenesis;GO:0021869//forebrain ventricular zone progenitor cell division;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0042661//regulation of mesodermal cell fate specification;GO:0030324//lung development;GO:0060638//mesenchymal-epithelial cell signaling gi|767950684|ref|XP_011542752.1|/0/PREDICTED: fibroblast growth factor receptor 1 isoform X11 [Homo sapiens] 66520 1803 12.91666667 13.33333333 0.04580369 Up 0.1537854 2610001J05Rik RIKEN cDNA 2610001J05 gene - - - - - 56032 1473 12.23 12.64666667 0.048332774 Up 0.1537854 Nprl2 nitrogen permease regulator-like 2 K20405|1|0.0|776|cjc:100408834|nitrogen permease regulator 2-like protein GO:0044424 GO:0016301//kinase activity GO:0006464//cellular protein modification process;GO:0043549//regulation of kinase activity gi|403291169|ref|XP_003936671.1|/0/PREDICTED: nitrogen permease regulator 2-like protein isoform X2 [Saimiri boliviensis boliviensis] 74229 4438 0.573333333 0.486666667 -0.236440196 Down 0.15374779 Paqr8 progestin and adipoQ receptor family member VIII K07297|1|9e-16|89.4|smm:Smp_057130|adiponectin receptor GO:0031224//intrinsic component of membrane GO:0008289//lipid binding GO:0007292//female gamete generation;GO:0048869//cellular developmental process gi|40254346|ref|NP_083105.3|/0/membrane progestin receptor beta [Mus musculus] 14058 2503 0.596666667 0.506666667 -0.235888264 Down 0.15374779 F10 coagulation factor X K01314|1|0.0|929|mmu:14058|coagulation factor X [EC:3.4.21.6] GO:0043227//membrane-bounded organelle;GO:0043227//membrane-bounded organelle GO:0004175//endopeptidase activity;GO:0046872//metal ion binding;GO:0008289//lipid binding;GO:0004175//endopeptidase activity;GO:0046872//metal ion binding;GO:0008289//lipid binding GO:0019538//protein metabolic process;GO:0007599//hemostasis;GO:0019538//protein metabolic process;GO:0007599//hemostasis gi|74213086|dbj|BAE41684.1|/0/unnamed protein product [Mus musculus] 13607 4913.25 0.573333333 0.486666667 -0.236440196 Down 0.15374779 Eda ectodysplasin-A K05480|1|5e-108|395|mmu:13607|ectodysplasin-A - - - - 242669 2084 0.586666667 0.496666667 -0.240263098 Down 0.15374779 Azin2 antizyme inhibitor 2 K01583|1|0.0|641|mmu:242669|arginine decarboxylase [EC:4.1.1.19] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0008047//enzyme activator activity;GO:0005488//binding;GO:0016831//carboxy-lyase activity;GO:0008047//enzyme activator activity;GO:0005488//binding;GO:0016831//carboxy-lyase activity GO:0006595//polyamine metabolic process;GO:1901605;GO:0044093;GO:0006595//polyamine metabolic process;GO:1901605;GO:0044093 gi|50925583|gb|AAH78981.1|/0/Similar to ornithine decarboxylase-like protein [Rattus norvegicus] 12556 2974 0.433333333 0.35 -0.308122295 Down 0.153728986 Cdh16 cadherin 16 "K06810|1|0.0|1655|mmu:12556|cadherin 16, KSP-cadherin" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0043169//cation binding;GO:0043169//cation binding GO:0016337//single organismal cell-cell adhesion;GO:0016337//single organismal cell-cell adhesion;GO:0016337//single organismal cell-cell adhesion gi|357933654|ref|NP_001239557.1|/0/cadherin-16 isoform 3 precursor [Mus musculus] 13482 5268 0.346666667 0.43 0.310787537 Up 0.153728986 Dpp4 dipeptidylpeptidase 4 K01278|1|0.0|1506|mmu:13482|dipeptidyl-peptidase 4 [EC:3.4.14.5] "GO:0005911//cell-cell junction;GO:0030027//lamellipodium;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031253//cell projection membrane;GO:0031224//intrinsic component of membrane;GO:0005911//cell-cell junction;GO:0030027//lamellipodium;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031253//cell projection membrane;GO:0031224//intrinsic component of membrane" GO:0004175//endopeptidase activity;GO:0008238//exopeptidase activity;GO:0033218//amide binding;GO:0042802//identical protein binding;GO:0019899//enzyme binding;GO:0004175//endopeptidase activity;GO:0008238//exopeptidase activity;GO:0033218//amide binding;GO:0042802//identical protein binding;GO:0019899//enzyme binding GO:0022407//regulation of cell-cell adhesion;GO:0008283//cell proliferation;GO:0031294//lymphocyte costimulation;GO:0010715//regulation of extracellular matrix disassembly;GO:0002456//T cell mediated immunity;GO:0006950//response to stress;GO:0016477//cell migration;GO:0019538//protein metabolic process;GO:0022407//regulation of cell-cell adhesion;GO:0008283//cell proliferation;GO:0031294//lymphocyte costimulation;GO:0010715//regulation of extracellular matrix disassembly;GO:0002456//T cell mediated immunity;GO:0006950//response to stress;GO:0016477//cell migration;GO:0019538//protein metabolic process gi|227116292|ref|NP_001153015.1|/0/dipeptidyl peptidase 4 isoform 2 [Mus musculus] 22147 1573 0.33 0.41 0.313157885 Up 0.153728986 Tuba3b "tubulin, alpha 3B" K07374|1|0.0|858|ocu:100349209|tubulin alpha GO:0032991//macromolecular complex;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0005198//structural molecule activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0044763;GO:0006458//'de novo' protein folding;GO:0043623//cellular protein complex assembly;GO:0009154//purine ribonucleotide catabolic process gi|291414495|ref|XP_002723497.1|/0/PREDICTED: tubulin alpha-3E chain [Oryctolagus cuniculus] 330222 8513 0.26 0.193333333 -0.427421224 Down 0.153700779 Sdk1 sidekick cell adhesion molecule 1 K16353|1|0.0|4155|mmu:330222|protein sidekick GO:0031224//intrinsic component of membrane - GO:0022610 gi|164518930|ref|NP_808547.3|/0/protein sidekick-1 [Mus musculus] 19317 5013.91 34.51666667 33.59333333 -0.039118192 Down 0.153644364 Qk quaking K14945|1|4e-151|539|ecb:100033866|protein quaking GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding GO:0050658//RNA transport;GO:0006412//translation;GO:0001676//long-chain fatty acid metabolic process;GO:0006396//RNA processing;GO:0007281//germ cell development;GO:0008366//axon ensheathment;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0050658//RNA transport;GO:0006412//translation;GO:0001676//long-chain fatty acid metabolic process;GO:0006396//RNA processing;GO:0007281//germ cell development;GO:0008366//axon ensheathment;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0050658//RNA transport;GO:0006412//translation;GO:0001676//long-chain fatty acid metabolic process;GO:0006396//RNA processing;GO:0007281//germ cell development;GO:0008366//axon ensheathment;GO:0048646//anatomical structure formation involved in morphogenesis gi|7542351|gb|AAF63414.1|AF142419_1/3.64531e-172/QUAKING isoform 6 [Homo sapiens] 68133 1337 37.25333333 36.34333333 -0.035678773 Down 0.15358795 Gcsh glycine cleavage system protein H (aminomethyl carrier) K02437|1|3e-90|334|mmu:68133|glycine cleavage system H protein GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding GO:0006546//glycine catabolic process "gi|13386066|ref|NP_080848.1|/2.48798e-89/glycine cleavage system H protein, mitochondrial precursor [Mus musculus]" 66629 2657 31.37333333 30.46333333 -0.042465008 Down 0.15358795 Golph3 golgi phosphoprotein 3 K15620|1|4e-133|478|rno:78961|golgi phosphoprotein 3 GO:0000139//Golgi membrane;GO:0005740//mitochondrial envelope;GO:0005635//nuclear envelope GO:0005488//binding GO:0009967//positive regulation of signal transduction;GO:0007005//mitochondrion organization gi|14140240|ref|NP_079949.1|/3.35352e-132/Golgi phosphoprotein 3 [Mus musculus] 229320 2849 0.22 0.293333333 0.415037499 Up 0.153531536 Clrn1 clarin 1 - GO:0031224//intrinsic component of membrane;GO:0031252//cell leading edge;GO:0042995//cell projection;GO:0031224//intrinsic component of membrane;GO:0031252//cell leading edge;GO:0042995//cell projection;GO:0031224//intrinsic component of membrane;GO:0031252//cell leading edge;GO:0042995//cell projection - GO:0050905//neuromuscular process;GO:0050954//sensory perception of mechanical stimulus;GO:0010591//regulation of lamellipodium assembly;GO:0030036//actin cytoskeleton organization;GO:0002093//auditory receptor cell morphogenesis;GO:0007601//visual perception;GO:0006928//movement of cell or subcellular component;GO:0050905//neuromuscular process;GO:0050954//sensory perception of mechanical stimulus;GO:0010591//regulation of lamellipodium assembly;GO:0030036//actin cytoskeleton organization;GO:0002093//auditory receptor cell morphogenesis;GO:0007601//visual perception;GO:0006928//movement of cell or subcellular component;GO:0050905//neuromuscular process;GO:0050954//sensory perception of mechanical stimulus;GO:0010591//regulation of lamellipodium assembly;GO:0030036//actin cytoskeleton organization;GO:0002093//auditory receptor cell morphogenesis;GO:0007601//visual perception;GO:0006928//movement of cell or subcellular component gi|24415398|ref|NP_700434.1|/6.20957e-130/clarin-1 isoform 2 [Mus musculus] 234825 2083 7.25 6.95 -0.060968017 Down 0.153484524 Klhdc4 kelch domain containing 4 K20285|1|3e-11|73.2|xtr:100492747|Rab9 effector protein with kelch motifs;K10317|3|2e-10|70.5|tca:658311|F-box protein 42 - - - gi|255683384|ref|NP_663580.2|/0/kelch domain-containing protein 4 [Mus musculus] 11487 4624 7.27 6.97 -0.060796708 Down 0.153484524 Adam10 a disintegrin and metallopeptidase domain 10 K06704|1|0.0|1477|mmu:11487|disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81] "GO:0044327//dendritic spine head;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031224//intrinsic component of membrane" GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0019900//kinase binding GO:0002274;GO:0038127//ERBB signaling pathway;GO:0007155//cell adhesion;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0008283//cell proliferation;GO:0043009//chordate embryonic development;GO:0006509//membrane protein ectodomain proteolysis;GO:0034097//response to cytokine;GO:0006464//cellular protein modification process;GO:0002761//regulation of myeloid leukocyte differentiation;GO:0016049//cell growth;GO:0051169//nuclear transport gi|150378458|ref|NP_031425.2|/0/disintegrin and metalloproteinase domain-containing protein 10 precursor [Mus musculus] 67089 1564 28.84333333 29.74 0.044166745 Up 0.153437512 Psmc6 "proteasome (prosome, macropain) 26S subunit, ATPase, 6" K03064|1|0.0|754|amj:102575425|26S proteasome regulatory subunit T4 GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0000502//proteasome complex;GO:0044444//cytoplasmic part GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0006915//apoptotic process;GO:0044764;GO:0051320;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0009154//purine ribonucleotide catabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|213972598|ref|NP_001093979.1|/0/26S protease regulatory subunit 10B [Rattus norvegicus] 238252 1374 0.076666667 0.133333333 0.798366139 Up 0.153437512 Gpr135 G protein-coupled receptor 135 K08427|1|0.0|706|mmu:238252|G protein-coupled receptor 135 GO:0016020//membrane GO:0004871//signal transducer activity GO:0007165//signal transduction gi|32306524|ref|NP_861417.1|/0/probable G-protein coupled receptor 135 [Mus musculus] 93882 3615 0.143333333 0.083333333 -0.782408565 Down 0.153437512 Pcdhb11 protocadherin beta 11 K16494|1|0.0|1436|mmu:93882|protocadherin beta GO:0016021//integral component of membrane;GO:0030054//cell junction GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|148747868|ref|NP_444366.3|/0/protocadherin beta 11 precursor [Mus musculus] 77633 2756 0.15 0.086666667 -0.791413378 Down 0.153437512 4930594C11Rik G1 to S phase transition pseudogene K03267|1|1e-150|311|lve:103086478|peptide chain release factor subunit 3 - - - gi|466010897|ref|XP_004270217.1|/3.63681e-150/PREDICTED: eukaryotic peptide chain release factor GTP-binding subunit ERF3A [Orcinus orca] 67166 2928 35.44333333 36.34 0.036044128 Up 0.153437512 Arl8b ADP-ribosylation factor-like 8B K07955|1|7e-107|383|rro:104664216|ADP-ribosylation factor-like protein 8 GO:0005764//lysosome;GO:0005770//late endosome;GO:0005819//spindle GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0015631//tubulin binding GO:0009154//purine ribonucleotide catabolic process;GO:0000087//mitotic M phase;GO:0035556//intracellular signal transduction gi|589944812|ref|XP_006985095.1|/1.13429e-112/PREDICTED: ADP-ribosylation factor-like protein 8B [Peromyscus maniculatus bairdii] 73910 3616 3.526666667 3.33 -0.082783044 Down 0.153409305 Arhgap18 Rho GTPase activating protein 18 K08773|1|8e-17|92.4|bfo:BRAFLDRAFT_80737|RalA-binding protein 1;K10360|2|9e-16|89.0|tca:656579|myosin IX;K08878|5|8e-15|85.9|lcm:102347322|breakpoint cluster region protein [EC:2.7.11.1] - - - - 66631 3472 3.956666667 3.753333333 -0.076113108 Down 0.153409305 Mfsd14b major facilitator superfamily domain containing 14B "K14613|1|3e-10|70.5|tca:664418|MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1/3;K08214|2|5e-06|56.6|dre:559752|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 18" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763 gi|142349203|ref|NP_598441.3|/0/hippocampus abundant transcript-like protein 1 [Mus musculus] 11781 1734 3.673333333 3.87 0.075243748 Up 0.153409305 Ap4m1 "adaptor-related protein complex AP-4, mu 1" K12402|1|0.0|833|mmu:11781|AP-4 complex subunit mu-1 - - - - 269994 3924 3.376666667 3.58 0.084359819 Up 0.153409305 Gsg1l GSG1-like "K11167|1|3e-55|220|nle:100587094|dehydrogenase/reductase SDR family member 7C [EC:1.1.-.-];K14356|2|1e-14|85.5|bfo:BRAFLDRAFT_199004|solute carrier organic anion transporter family, member 5A" GO:0031224//intrinsic component of membrane;GO:0045202//synapse - GO:0010469//regulation of receptor activity gi|157951733|ref|NP_001094958.1|/1.18897e-160/germ cell-specific gene 1-like protein precursor [Mus musculus] 20440 4207.07 3.663333333 3.863333333 0.07668918 Up 0.153409305 St6gal1 "beta galactoside alpha 2,6 sialyltransferase 1" "K00778|1|0.0|843|mmu:20440|beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1) [EC:2.4.99.1]" GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane GO:0008373//sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0008373//sialyltransferase activity GO:0006955//immune response;GO:0006493//protein O-linked glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006955//immune response;GO:0006493//protein O-linked glycosylation;GO:0006487//protein N-linked glycosylation;GO:0006955//immune response;GO:0006493//protein O-linked glycosylation;GO:0006487//protein N-linked glycosylation "gi|22122355|ref|NP_666045.1|/0/beta-galactoside alpha-2,6-sialyltransferase 1 [Mus musculus]" 246104 3767 3.506666667 3.706666667 0.080022083 Up 0.153409305 Rhbdl3 "rhomboid, veinlet-like 3 (Drosophila)" K02857|1|0.0|719|mmu:246104|rhomboid-related protein 1/2/3 [EC:3.4.21.105] GO:0031224//intrinsic component of membrane "GO:0046872//metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process "gi|148683687|gb|EDL15634.1|/0/rhomboid, veinlet-like 3 (Drosophila), isoform CRA_b, partial [Mus musculus]" 235439 15229 3.686666667 3.49 -0.079089943 Down 0.153409305 Herc1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 K10594|1|0.0|8726|mmu:235439|E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26] - - - - 12013 5858 3.886666667 3.686666667 -0.076216403 Down 0.153409305 Bach1 "BTB and CNC homology 1, basic leucine zipper transcription factor 1" K09042|1|0.0|1384|mmu:12013|transcription regulator BACH - - - - 12212 7401 0.443333333 0.36 -0.300394933 Down 0.153362293 Chic1 cysteine-rich hydrophobic domain 1 - GO:0031982//vesicle;GO:0016020//membrane - - gi|984138672|ref|XP_015361355.1|/4.714e-68/PREDICTED: cysteine-rich hydrophobic domain-containing protein 1 [Marmota marmota marmota] 27096 1315 31.76666667 30.88 -0.040840961 Down 0.153296476 Trappc3 trafficking protein particle complex 3 K20302|1|5e-98|360|rno:362599|trafficking protein particle complex subunit 3 GO:0012505//endomembrane system;GO:0044444//cytoplasmic part;GO:0005801//cis-Golgi network GO:0005488//binding GO:0016482//cytosolic transport "gi|354459836|pdb|2J3R|A/8.3322e-98/Chain A, The Crystal Structure Of The Bet3-Trs31 Heterodimer." 232431 2072 0.996666667 0.883333333 -0.174153125 Down 0.153221257 Gprc5a "G protein-coupled receptor, family C, group 5, member A" K08468|1|2e-175|618|mmu:232431|G protein-coupled receptor family C group 5 member A GO:0043227//membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|225543465|ref|NP_852109.2|/1.53875e-174/retinoic acid-induced protein 3 [Mus musculus] 338363 3046 0.92 1.033333333 0.167599948 Up 0.153221257 Tmem241 transmembrane protein 241 K15281|1|8e-07|48.1|clv:102097286|solute carrier family 35 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|576067799|ref|NP_001276595.1|/3.60016e-168/transmembrane protein 241 isoform 1 [Mus musculus] 58194 3869.06 34.68 33.80333333 -0.036938381 Down 0.153221257 Sh3kbp1 SH3-domain kinase binding protein 1 K12470|1|0.0|498|ptg:102963969|SH3 domain-containing kinase-binding protein 1 GO:0043232;GO:0005924//cell-substrate adherens junction;GO:0042995//cell projection;GO:0012506//vesicle membrane;GO:0044444//cytoplasmic part;GO:0030054//cell junction;GO:0043232;GO:0031982//vesicle;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043232;GO:0005924//cell-substrate adherens junction;GO:0042995//cell projection;GO:0012506//vesicle membrane;GO:0043232;GO:0031982//vesicle;GO:0042995//cell projection;GO:0044424;GO:0043229//intracellular organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043232;GO:0031982//vesicle;GO:0042995//cell projection "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019904//protein domain specific binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019904//protein domain specific binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019904//protein domain specific binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019904//protein domain specific binding;GO:0005488//binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019904//protein domain specific binding" GO:0016192//vesicle-mediated transport;GO:0006996//organelle organization;GO:0022604//regulation of cell morphogenesis;GO:0048870//cell motility;GO:0006915//apoptotic process;GO:0006796//phosphate-containing compound metabolic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0016192//vesicle-mediated transport;GO:0006996//organelle organization;GO:0022604//regulation of cell morphogenesis;GO:0048870//cell motility;GO:0006915//apoptotic process;GO:0006796//phosphate-containing compound metabolic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0016192//vesicle-mediated transport;GO:0006996//organelle organization;GO:0022604//regulation of cell morphogenesis;GO:0048870//cell motility;GO:0006915//apoptotic process;GO:0006796//phosphate-containing compound metabolic process;GO:0016192//vesicle-mediated transport;GO:0012501//programmed cell death;GO:0006996//organelle organization;GO:0022604//regulation of cell morphogenesis;GO:0048870//cell motility;GO:0006796//phosphate-containing compound metabolic process;GO:0006996//organelle organization;GO:0022604//regulation of cell morphogenesis;GO:0048870//cell motility;GO:0006996//organelle organization;GO:0022604//regulation of cell morphogenesis;GO:0048870//cell motility;GO:0006915//apoptotic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0016192//vesicle-mediated transport;GO:0012501//programmed cell death;GO:0006996//organelle organization;GO:0022604//regulation of cell morphogenesis;GO:0048870//cell motility;GO:0006796//phosphate-containing compound metabolic process gi|27151744|ref|NP_067364.2|/0/SH3 domain-containing kinase-binding protein 1 isoform 2 [Mus musculus] 74511 2204 0.893333333 1.006666667 0.172315549 Up 0.153221257 Lrrc17 leucine rich repeat containing 17 K06839|1|1e-27|127|bfo:BRAFLDRAFT_86604|slit 2 - - - - 97423 2751 1.016666667 0.906666667 -0.165202591 Down 0.153221257 R74862 expressed sequence R74862 - - - - "gi|148686245|gb|EDL18192.1|/4.18898e-69/expressed sequence R74862, partial [Mus musculus]" 320172 1762 0.93 1.043333333 0.165897535 Up 0.153221257 E230016M11Rik RIKEN cDNA E230016M11 gene K04402|1|1e-39|167|mmu:13197|growth arrest and DNA-damage-inducible protein GO:0043231//intracellular membrane-bounded organelle GO:0044212//transcription regulatory region DNA binding GO:0012501//programmed cell death;GO:0035556//intracellular signal transduction;GO:0006259//DNA metabolic process;GO:0022402//cell cycle process;GO:0010212//response to ionizing radiation;GO:0051726//regulation of cell cycle;GO:0033554//cellular response to stress;GO:0001933//negative regulation of protein phosphorylation;GO:0072593//reactive oxygen species metabolic process;GO:0009612//response to mechanical stimulus gi|6681149|ref|NP_031862.1|/9.97213e-39/growth arrest and DNA damage-inducible protein GADD45 alpha [Mus musculus] 69053 4074 10.94666667 11.35666667 0.05304782 Up 0.153202452 1810013L24Rik RIKEN cDNA 1810013L24 gene - - - - gi|145587086|ref|NP_001074869.1|/1.63671e-128/UPF0472 protein C16orf72 homolog [Mus musculus] 70465 3553 12.93333333 12.52333333 -0.046475536 Down 0.153202452 Wdr77 WD repeat domain 77 K13221|1|0.0|679|mmu:70465|methylosome protein 50 GO:0031981//nuclear lumen GO:0003713//transcription coactivator activity GO:0050680//negative regulation of epithelial cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0002067//glandular epithelial cell differentiation gi|19263322|ref|NP_081708.1|/0/methylosome protein 50 [Mus musculus] 20019 6145 11.53 11.11666667 -0.052668252 Down 0.153202452 Polr1a polymerase (RNA) I polypeptide A K02999|1|0.0|3165|mmu:20019|DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6] GO:0044452//nucleolar part GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0034062//RNA polymerase activity "GO:0006351//transcription, DNA-templated" gi|256985188|ref|NP_033114.3|/0/DNA-directed RNA polymerase I subunit RPA1 [Mus musculus] 72354 2569 10.84 11.25 0.053560245 Up 0.153202452 Ttc4 tetratricopeptide repeat domain 4 K19870|1|1e-12|78.2|chx:102190335|sperm-associated antigen 1 - - - gi|30794388|ref|NP_082485.1|/0/tetratricopeptide repeat protein 4 isoform 1 [Mus musculus] 108099 2955.91 11.26333333 10.85333333 -0.053495651 Down 0.153202452 Prkag2 "protein kinase, AMP-activated, gamma 2 non-catalytic subunit" "K07200|1|0.0|886|mmu:108099|5'-AMP-activated protein kinase, regulatory gamma subunit" - - - gi|887242656|ref|NP_001297409.1|/0/5'-AMP-activated protein kinase subunit gamma-2 isoform 4 [Mus musculus] 192160 3764 11.97 12.37666667 0.048199662 Up 0.153202452 Casc3 cancer susceptibility candidate 3 K14323|1|0.0|1001|mmu:192160|protein CASC3 GO:0043234//protein complex;GO:0016604//nuclear body;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding;GO:0044389//ubiquitin-like protein ligase binding GO:0006412//translation;GO:0050896//response to stimulus;GO:0006396//RNA processing;GO:0050658//RNA transport gi|160333568|ref|NP_619601.2|/0/protein CASC3 [Mus musculus] 23988 3808 11.31 10.89666667 -0.053712053 Down 0.153202452 Pin1 protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 K09578|1|2e-90|337|mmu:23988|peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8] GO:0016604//nuclear body GO:0045309//protein phosphorylated amino acid binding;GO:0019901//protein kinase binding;GO:0016859//cis-trans isomerase activity;GO:0016597//amino acid binding GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:0043409//negative regulation of MAPK cascade;GO:0018208//peptidyl-proline modification;GO:0006952//defense response;GO:0031398//positive regulation of protein ubiquitination;GO:0000910//cytokinesis;GO:0008283//cell proliferation;GO:0001818//negative regulation of cytokine production;GO:0040013//negative regulation of locomotion;GO:0007067//mitotic nuclear division gi|12963653|ref|NP_075860.1|/1.81789e-89/peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [Mus musculus] 78816 3945 1.463333333 1.596666667 0.125804716 Up 0.153146038 Gmip Gem-interacting protein "K10360|1|3e-27|127|mze:101479351|myosin IX;K02649|2|6e-27|126|bfo:BRAFLDRAFT_91712|phosphoinositide-3-kinase, regulatory subunit;K20315|5|6e-26|122|obi:106877701|Rho GTPase-activating protein 21/23" GO:0044464 GO:0043169//cation binding - "gi|148696806|gb|EDL28753.1|/0/Gem-interacting protein, isoform CRA_a, partial [Mus musculus]" 170753 13849 1.393333333 1.526666667 0.131844656 Up 0.153146038 Zfp704 zinc finger protein 704 - - - - - 99586 4437 1.386666667 1.516666667 0.129283017 Up 0.153146038 Dpyd dihydropyrimidine dehydrogenase K00207|1|0.0|2045|mmu:99586|dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2] GO:0044444//cytoplasmic part "GO:0000166//nucleotide binding;GO:0051536//iron-sulfur cluster binding;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0002061;GO:0004152//dihydroorotate dehydrogenase activity;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor" GO:0048511//rhythmic process;GO:0046104//thymidine metabolic process;GO:0006144//purine nucleobase metabolic process;GO:0006208//pyrimidine nucleobase catabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0031960//response to corticosteroid;GO:0009174;GO:0031667//response to nutrient levels gi|25140985|ref|NP_740748.1|/0/dihydropyrimidine dehydrogenase [NADP(+)] [Mus musculus] 67219 1677 1.336666667 1.466666667 0.133901287 Up 0.153146038 Med18 mediator complex subunit 18 K15135|1|3e-108|394|mmu:67219|mediator of RNA polymerase II transcription subunit 18 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0005488//binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" GO:0006366//transcription from RNA polymerase II promoter gi|795371422|ref|XP_011935272.1|/2.76717e-107/PREDICTED: mediator of RNA polymerase II transcription subunit 18 isoform X2 [Cercocebus atys] 12362 1533 0.713333333 0.816666667 0.195170953 Up 0.153136635 Casp1 caspase 1 K01370|1|0.0|808|mmu:12362|caspase 1 [EC:3.4.22.36];K04394|4|1e-146|522|pale:102887403|caspase 4 [EC:3.4.22.57] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0042995//cell projection GO:0004175//endopeptidase activity;GO:0005515//protein binding "GO:0032730//positive regulation of interleukin-1 alpha production;GO:0050663//cytokine secretion;GO:0007611//learning or memory;GO:0042748//circadian sleep/wake cycle, non-REM sleep;GO:0042116//macrophage activation;GO:0009612//response to mechanical stimulus;GO:0051604//protein maturation;GO:0046683//response to organophosphorus;GO:0006915//apoptotic process;GO:0000768//syncytium formation by plasma membrane fusion;GO:0032731//positive regulation of interleukin-1 beta production;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0051881//regulation of mitochondrial membrane potential;GO:0030323//respiratory tube development;GO:0012502//induction of programmed cell death;GO:0048565//digestive tract development;GO:0006950//response to stress;GO:0002237//response to molecule of bacterial origin" gi|86198305|ref|NP_033937.2|/0/caspase-1 [Mus musculus] 97541 2501 35.10333333 35.97 0.035186127 Up 0.153136635 Qars glutaminyl-tRNA synthetase K01886|1|0.0|1582|mmu:97541|glutaminyl-tRNA synthetase [EC:6.1.1.18] - - - - 53311 1856 0.686666667 0.786666667 0.196142522 Up 0.153136635 Mybph myosin binding protein H "K12568|1|3e-136|488|fab:101815991|myosin-binding protein C, cardiac-type" GO:0016459//myosin complex - - gi|56676318|ref|NP_058029.2|/0/myosin-binding protein H [Mus musculus] 751864 618 0.086666667 0.146666667 0.7589919 Up 0.153080221 Gm9733 predicted gene 9733 K06551|1|1e-85|317|mmu:751864|signal-regulatory protein alpha/beta1/gamma - - - gi|68303967|gb|AAY89666.1|/9.85038e-85/SIRP beta 1 like 2 protein [Mus musculus] 545611 4130 0.136666667 0.08 -0.772589504 Down 0.153080221 Fam205a2 "family with sequence similarity 205, member A2" - - - - gi|147901636|ref|NP_001078999.1|/0/protein FAM205A [Mus musculus] 243967 1761 0.09 0.15 0.736965594 Up 0.153080221 Ntn5 netrin 5 K06843|1|1e-47|130|xtr:779839|netrin 1 - - - gi|125490394|ref|NP_001028528.2|/0/netrin-5 isoform a precursor [Mus musculus] 22264 639 0.09 0.15 0.736965594 Up 0.153080221 Prap1 proline-rich acidic protein 1 - - - - gi|899433|gb|AAC24897.1|/3.5591e-72/proline-rich acidic protein [Mus musculus] 100503879 1002 0.156666667 0.093333333 -0.74723393 Down 0.153080221 Gm5901 predicted gene 5901 - - - - gi|307612000|ref|NP_001182656.1|/3.06095e-165/uncharacterized protein C11orf42 homolog [Mus musculus] 381622 2947 0.15 0.09 -0.736965594 Down 0.153080221 5031410I06Rik RIKEN cDNA 5031410I06 gene - - - - gi|170650703|ref|NP_997540.2|/7.37157e-128/uncharacterized protein LOC381622 [Mus musculus] 332993 603 0.09 0.15 0.736965594 Up 0.153080221 Gm5129 predicted gene 5129 - - - - gi|26345606|dbj|BAC36454.1|/8.21208e-49/unnamed protein product [Mus musculus] 330052 1964 0.093333333 0.156666667 0.74723393 Up 0.153080221 A930003O13Rik RIKEN cDNA A930003O13 gene - - - - gi|593733423|ref|XP_007112182.1|/1.73653e-95/PREDICTED: lipoma HMGIC fusion partner-like 3 protein-like [Physeter catodon] 319530 3254 0.136666667 0.08 -0.772589504 Down 0.153080221 Zfp750 zinc finger protein 750 K14562|1|1e-07|62.0|apla:101803153|Treacher Collins syndrome protein;K11294|2|9e-07|58.9|dsi:Dsimw501_GD17650|nucleolin GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding" GO:0048869//cellular developmental process;GO:0009888//tissue development;GO:0006366//transcription from RNA polymerase II promoter "gi|148702896|gb|EDL34843.1|/0/zinc finger protein 750, partial [Mus musculus]" 269120 1636 0.15 0.09 -0.736965594 Down 0.153080221 Optc opticin K08128|1|1e-129|465|mmu:269120|opticin GO:0031012//extracellular matrix;GO:0031012//extracellular matrix;GO:0031012//extracellular matrix;GO:0031012//extracellular matrix - - gi|238018139|ref|NP_001153894.1|/4.80209e-134/opticin isoform 4 [Mus musculus] 245532 2002 0.08 0.136666667 0.772589504 Up 0.153080221 Awat2 acyl-CoA wax alcohol acyltransferase 2 K11156|1|0.0|665|mmu:245532|diacylglycerol O-acyltransferase 2-like protein 4 [EC:2.3.1.75 2.3.1.76] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008374//O-acyltransferase activity;GO:0008374//O-acyltransferase activity GO:0006633//fatty acid biosynthetic process;GO:0006633//fatty acid biosynthetic process gi|50355956|ref|NP_808414.2|/0/acyl-CoA wax alcohol acyltransferase 2 isoform 1 [Mus musculus] 233040 1961 0.15 0.09 -0.736965594 Down 0.153080221 Fbxo27 F-box protein 27 K10102|1|5e-143|510|mmu:233040|F-box protein 27 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex - GO:0009057//macromolecule catabolic process;GO:0009057//macromolecule catabolic process gi|568945517|ref|XP_006539925.1|/8.47953e-151/PREDICTED: F-box only protein 27 isoform X2 [Mus musculus] 192663 3626 0.083333333 0.14 0.748461233 Up 0.153080221 Abcg4 "ATP-binding cassette, sub-family G (WHITE), member 4" "K05680|1|0.0|1188|mmu:192663|ATP-binding cassette, subfamily G (WHITE), member 4" GO:0031224//intrinsic component of membrane GO:0042802//identical protein binding;GO:0015248//sterol transporter activity;GO:0046983//protein dimerization activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0030301//cholesterol transport;GO:0044763 "gi|148693626|gb|EDL25573.1|/0/mCG141862, isoform CRA_c, partial [Mus musculus]" 59038 1468 34.35 35.20666667 0.035538542 Up 0.153014404 Pxmp4 peroxisomal membrane protein 4 K13350|1|2e-103|379|mmu:59038|peroxisomal membrane protein 4 GO:0044439;GO:0031224//intrinsic component of membrane - - gi|10946966|ref|NP_067509.1|/1.30787e-102/peroxisomal membrane protein 4 [Mus musculus] 234852 2188 29.90333333 30.75666667 0.040592845 Up 0.152948588 Chmp1a charged multivesicular body protein 1A K12197|1|2e-89|332|ngi:103741397|charged multivesicular body protein 1 GO:0034399//nuclear periphery;GO:0015630//microtubule cytoskeleton;GO:0000228//nuclear chromosome;GO:0005768//endosome GO:0005515//protein binding GO:0006810//transport;GO:0045013//carbon catabolite repression of transcription;GO:0000084//mitotic S phase;GO:0045184//establishment of protein localization;GO:0000070//mitotic sister chromatid segregation gi|674066860|ref|XP_008840389.1|/1.79692e-88/PREDICTED: charged multivesicular body protein 1a [Nannospalax galili] 70294 1617.83 27.76 28.61333333 0.043680007 Up 0.152948588 Rnf126 ring finger protein 126 K11982|1|3e-154|547|mmu:70294|E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27] - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - gi|21362321|ref|NP_653111.1|/3.97805e-118/E3 ubiquitin-protein ligase RNF126 [Mus musculus] 13527 2190.48 32.60333333 31.76666667 -0.037505758 Down 0.152854564 Dtna dystrobrevin alpha K10366|1|9e-52|209|lgi:LOTGIDRAFT_169302|dystrophin GO:0044424;GO:0016010//dystrophin-associated glycoprotein complex;GO:0044424;GO:0016010//dystrophin-associated glycoprotein complex;GO:0044424;GO:0016010//dystrophin-associated glycoprotein complex;GO:0044424;GO:0016010//dystrophin-associated glycoprotein complex;GO:0044424;GO:0016010//dystrophin-associated glycoprotein complex;GO:0044424;GO:0016010//dystrophin-associated glycoprotein complex;GO:0044424;GO:0016010//dystrophin-associated glycoprotein complex;GO:0044424;GO:0016010//dystrophin-associated glycoprotein complex GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - "gi|148664561|gb|EDK96977.1|/0/dystrobrevin alpha, isoform CRA_b, partial [Mus musculus]" 217684 5038.54 33 33.83333333 0.035979297 Up 0.152722931 Susd6 sushi domain containing 6 - - - - - 214239 4716 11.42 11.02333333 -0.051002106 Down 0.152675919 A430105I19Rik RIKEN cDNA A430105I19 gene - - - - gi|74215754|dbj|BAE23419.1|/0/unnamed protein product [Mus musculus] 67015 2477 11.59333333 11.99 0.048536227 Up 0.152675919 Ccdc91 coiled-coil domain containing 91 K13356|1|4e-18|96.3|bfo:BRAFLDRAFT_90375|alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84];K16462|3|9e-10|68.6|cmy:102941405|centrosomal protein CEP164;K16476|4|1e-09|68.2|dre:571879|ninein GO:0031981//nuclear lumen GO:0005515//protein binding GO:0045184//establishment of protein localization gi|27532950|ref|NP_080187.2|/0/coiled-coil domain-containing protein 91 [Mus musculus] 59030 2841.95 11.15666667 10.76 -0.052227972 Down 0.152675919 Mkks McKusick-Kaufman syndrome K09492|1|3e-140|501|mmu:59030|McKusick-Kaufman syndrome protein GO:0005929//cilium;GO:0005815//microtubule organizing center;GO:0005929//cilium;GO:0005815//microtubule organizing center;GO:0005929//cilium;GO:0043232;GO:0005929//cilium;GO:0005815//microtubule organizing center GO:0032550;GO:0032550;GO:0032550;GO:0032550 GO:0051705;GO:0010467//gene expression;GO:0032099//negative regulation of appetite;GO:0021543//pallium development;GO:0019221//cytokine-mediated signaling pathway;GO:0007601//visual perception;GO:0042384//cilium assembly;GO:0014820//tonic smooth muscle contraction;GO:0009887//organ morphogenesis;GO:0043623//cellular protein complex assembly;GO:0007281//germ cell development;GO:0060295;GO:0035264//multicellular organism growth;GO:0021544//subpallium development;GO:0009725//response to hormone;GO:0050880//regulation of blood vessel size;GO:0008217//regulation of blood pressure;GO:0007606//sensory perception of chemical stimulus;GO:0019538//protein metabolic process;GO:0051705;GO:0010467//gene expression;GO:0032099//negative regulation of appetite;GO:0021543//pallium development;GO:0019221//cytokine-mediated signaling pathway;GO:0007601//visual perception;GO:0042384//cilium assembly;GO:0014820//tonic smooth muscle contraction;GO:0009887//organ morphogenesis;GO:0043623//cellular protein complex assembly;GO:0007281//germ cell development;GO:0060295;GO:0035264//multicellular organism growth;GO:0021544//subpallium development;GO:0009725//response to hormone;GO:0050880//regulation of blood vessel size;GO:0008217//regulation of blood pressure;GO:0007606//sensory perception of chemical stimulus;GO:0019538//protein metabolic process;GO:0051705;GO:0010467//gene expression;GO:0032099//negative regulation of appetite;GO:0021543//pallium development;GO:0019221//cytokine-mediated signaling pathway;GO:0007601//visual perception;GO:0042384//cilium assembly;GO:0014820//tonic smooth muscle contraction;GO:0009887//organ morphogenesis;GO:0043623//cellular protein complex assembly;GO:0007281//germ cell development;GO:0060295;GO:0035264//multicellular organism growth;GO:0021544//subpallium development;GO:0009725//response to hormone;GO:0050880//regulation of blood vessel size;GO:0008217//regulation of blood pressure;GO:0007606//sensory perception of chemical stimulus;GO:0019538//protein metabolic process;GO:0051705;GO:0010467//gene expression;GO:0032099//negative regulation of appetite;GO:0021543//pallium development;GO:0019221//cytokine-mediated signaling pathway;GO:0007601//visual perception;GO:0042384//cilium assembly;GO:0014820//tonic smooth muscle contraction;GO:0009887//organ morphogenesis;GO:0043623//cellular protein complex assembly;GO:0007281//germ cell development;GO:0060295;GO:0035264//multicellular organism growth;GO:0021544//subpallium development;GO:0009725//response to hormone;GO:0050880//regulation of blood vessel size;GO:0008217//regulation of blood pressure;GO:0007606//sensory perception of chemical stimulus;GO:0019538//protein metabolic process gi|558757394|ref|NP_001273910.1|/0/McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin isoform 2 [Mus musculus] 12296 3814 11.06666667 10.66666667 -0.053111336 Down 0.152675919 Cacnb2 "calcium channel, voltage-dependent, beta 2 subunit" K04863|1|0.0|997|mmu:12296|voltage-dependent calcium channel beta-2 GO:0034704//calcium channel complex;GO:0034704//calcium channel complex;GO:0005886//plasma membrane;GO:0034704//calcium channel complex;GO:0005886//plasma membrane GO:0019900//kinase binding;GO:0005245//voltage-gated calcium channel activity;GO:0016247//channel regulator activity;GO:0019900//kinase binding;GO:0005245//voltage-gated calcium channel activity;GO:0016247//channel regulator activity;GO:0019900//kinase binding;GO:0005245//voltage-gated calcium channel activity;GO:0016247//channel regulator activity GO:0070588//calcium ion transmembrane transport;GO:0007267//cell-cell signaling;GO:0050953//sensory perception of light stimulus;GO:0070588//calcium ion transmembrane transport;GO:0007267//cell-cell signaling;GO:0050953//sensory perception of light stimulus;GO:0070588//calcium ion transmembrane transport;GO:0007267//cell-cell signaling;GO:0050953//sensory perception of light stimulus gi|828747400|ref|NP_001296448.1|/0/voltage-dependent L-type calcium channel subunit beta-2 isoform 3 [Mus musculus] 226856 7068.9 10.98666667 10.58333333 -0.053959651 Down 0.152675919 Lpgat1 lysophosphatidylglycerol acyltransferase 1 K13514|1|0.0|775|mmu:226856|lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0016740//transferase activity;GO:0016740//transferase activity GO:0006644//phospholipid metabolic process;GO:0006644//phospholipid metabolic process gi|74228729|dbj|BAE21857.1|/0/unnamed protein product [Mus musculus] 171504 3615 0.496666667 0.583333333 0.232042591 Up 0.15256309 Apobr apolipoprotein B receptor K19538|1|2e-06|57.8|mcc:702238|retinitis pigmentosa 1 GO:0034385;GO:0016020//membrane GO:0030228//lipoprotein particle receptor activity GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0006639//acylglycerol metabolic process;GO:0016125//sterol metabolic process gi|19923863|ref|NP_612183.1|/0/apolipoprotein B receptor [Mus musculus] 26405 10791 0.5 0.586666667 0.230612928 Up 0.15256309 Map3k2 mitogen-activated protein kinase kinase kinase 2 K04420|1|0.0|1148|mmu:26405|mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0043169//cation binding;GO:0019900//kinase binding "GO:0006351//transcription, DNA-templated;GO:0009612//response to mechanical stimulus;GO:0000187//activation of MAPK activity" gi|89257354|ref|NP_036076.2|/0/mitogen-activated protein kinase kinase kinase 2 [Mus musculus] 93893 3067 0.52 0.61 0.230297619 Up 0.15256309 Pcdhb22 protocadherin beta 22 K16494|1|0.0|1487|mmu:93893|protocadherin beta GO:0016021//integral component of membrane GO:0046872//metal ion binding GO:0048731//system development;GO:0016337//single organismal cell-cell adhesion gi|148728178|ref|NP_444377.3|/0/protocadherin beta-15 precursor [Mus musculus] 16526 3464.72 0.516666667 0.606666667 0.231670235 Up 0.15256309 Kcnk2 "potassium channel, subfamily K, member 2" K04913|1|0.0|788|mmu:16526|potassium channel subfamily K member 2 GO:0005887//integral component of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005887//integral component of plasma membrane GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0005267//potassium channel activity GO:0007267//cell-cell signaling;GO:0007166//cell surface receptor signaling pathway;GO:0042391//regulation of membrane potential;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0007166//cell surface receptor signaling pathway;GO:0042391//regulation of membrane potential;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0007166//cell surface receptor signaling pathway;GO:0042391//regulation of membrane potential;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0007166//cell surface receptor signaling pathway;GO:0042391//regulation of membrane potential;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|229577199|ref|NP_001153322.1|/0/potassium channel subfamily K member 2 isoform 1 [Mus musculus] 15260 4553 4.583333333 4.356666667 -0.073172478 Down 0.152553688 Hira histone cell cycle regulator K11293|1|0.0|1791|mmu:15260|protein HIRA/HIR1 - - - - 433938 6128 4.613333333 4.38 -0.074878667 Down 0.152553688 Mn1 meningioma 1 - - - - gi|124486985|ref|NP_001074704.1|/0/transcriptional activator MN1 [Mus musculus] 66714 1595 6.556666667 6.85 0.063141436 Up 0.152487871 4921524J17Rik RIKEN cDNA 4921524J17 gene - - - - gi|918611848|ref|XP_013374038.1|/7.42683e-42/PREDICTED: UPF0547 protein C16orf87 homolog [Chinchilla lanigera] 229521 4585 6.366666667 6.656666667 0.064261695 Up 0.152487871 Syt11 synaptotagmin XI K19911|1|0.0|813|mmu:229521|synaptotagmin-11 GO:0008021//synaptic vesicle;GO:0016021//integral component of membrane GO:0046872//metal ion binding;GO:0005543//phospholipid binding GO:0051234//establishment of localization gi|34328242|ref|NP_061274.2|/0/synaptotagmin-11 [Mus musculus] 68603 1202.33 7.24 6.946666667 -0.059668826 Down 0.152487871 Pmvk phosphomevalonate kinase K13273|1|3e-79|297|mmu:68603|phosphomevalonate kinase [EC:2.7.4.2] - - - - 83431 2387 29.22333333 28.41666667 -0.040383414 Down 0.152431457 Ndel1 nudE neurodevelopment protein 1 like 1 K16739|1|4e-173|610|chx:102176913|nuclear distribution protein NudE-like 1 GO:0043005//neuron projection;GO:0045111//intermediate filament cytoskeleton;GO:0000776//kinetochore;GO:0012505//endomembrane system;GO:0005875//microtubule associated complex;GO:0005815//microtubule organizing center GO:0008233//peptidase activity;GO:0015631//tubulin binding GO:0016055//Wnt signaling pathway;GO:0045104//intermediate filament cytoskeleton organization;GO:0031103//axon regeneration;GO:0006998//nuclear envelope organization;GO:0030307//positive regulation of cell growth;GO:0051648//vesicle localization;GO:0001832//blastocyst growth;GO:0021795//cerebral cortex cell migration;GO:0008088//axo-dendritic transport gi|545498102|ref|XP_850046.3|/6.92248e-174/PREDICTED: nuclear distribution protein nudE-like 1 isoform X1 [Canis lupus familiaris] 68020 1061 27.45333333 28.26 0.041780136 Up 0.152431457 Apopt1 "apoptogenic, mitochondrial 1" - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0035556//intracellular signal transduction;GO:0010822//positive regulation of mitochondrion organization;GO:0010661;GO:0035556//intracellular signal transduction;GO:0010822//positive regulation of mitochondrion organization;GO:0010661 "gi|21735435|ref|NP_080787.1|/1.16636e-109/apoptogenic protein 1, mitochondrial isoform 2 [Mus musculus]" 17713 3338 30.85666667 30.05333333 -0.038057206 Down 0.152224604 Grpel1 "GrpE-like 1, mitochondrial" K03687|1|4e-99|365|mmu:17713|molecular chaperone GrpE GO:0044429 GO:0042802//identical protein binding GO:0044267//cellular protein metabolic process "gi|13277394|ref|NP_077798.1|/3.15185e-98/grpE protein homolog 1, mitochondrial precursor [Mus musculus]" 209012 4093 0.143333333 0.086666667 -0.725825037 Down 0.152111776 Ulk4 unc-51-like kinase 4 K17545|1|0.0|2308|mmu:209012|serine/threonine-protein kinase ULK4 [EC:2.7.11.1] - - - gi|226958505|ref|NP_808257.2|/0/serine/threonine-protein kinase ULK4 [Mus musculus] 100038378 1982 0.16 0.096666667 -0.726981506 Down 0.152111776 Gm10433 predicted gene 10433 - - - - - 67052 2201 0.09 0.146666667 0.704544116 Up 0.152111776 Ndc80 NDC80 kinetochore complex component K11547|1|0.0|1180|mmu:67052|kinetochore protein NDC80 GO:0000778//condensed nuclear chromosome kinetochore GO:0005488//binding GO:0040001//establishment of mitotic spindle localization;GO:0007059//chromosome segregation;GO:0000087//mitotic M phase gi|217035142|ref|NP_075783.2|/0/kinetochore protein NDC80 homolog [Mus musculus] 18994 4730 0.03 0.083333333 1.473931188 Up 0.152102373 Pou3f4 "POU domain, class 3, transcription factor 4" "K09365|1|0.0|704|rno:29589|POU domain transcription factor, class 3" GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0043566//structure-specific DNA binding "GO:0050954//sensory perception of mechanical stimulus;GO:0048598//embryonic morphogenesis;GO:0021872//forebrain generation of neurons;GO:0043583//ear development;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process" "gi|6679427|ref|NP_032927.1|/0/POU domain, class 3, transcription factor 4 [Mus musculus]" 329404 2038 0.026666667 0.073333333 1.459431619 Up 0.152102373 Gm13497 predicted gene 13497 - - - - - 57811 4135 0.08 0.03 -1.415037499 Down 0.152102373 Rgr retinal G protein coupled receptor K04254|1|3e-154|549|mmu:57811|retinal G protein coupled receptor GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process;GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process;GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process "gi|148692948|gb|EDL24895.1|/8.29394e-155/retinal G protein coupled receptor, partial [Mus musculus]" 56419 3516 0.083333333 0.03 -1.473931188 Down 0.152102373 Diaph3 diaphanous related formin 3 K05745|1|0.0|2025|mmu:56419|diaphanous 3 GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle GO:0017016//Ras GTPase binding;GO:0008092//cytoskeletal protein binding GO:0007010//cytoskeleton organization gi|9789931|ref|NP_062644.1|/0/protein diaphanous homolog 3 [Mus musculus] 545700 3752 0.026666667 0.073333333 1.459431619 Up 0.152102373 Smarca5-ps "SWI/SNF related, matrix associated, actin depenent ragulator of chromatin, subfamily a, member 5, pseudogene" K11654|1|0.0|716|pss:102444002|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-] GO:0031010//ISWI-type complex;GO:0005694//chromosome GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding;GO:0003682//chromatin binding GO:0007275//multicellular organism development;GO:0034728//nucleosome organization;GO:0006342//chromatin silencing;GO:0006338//chromatin remodeling;GO:0009154//purine ribonucleotide catabolic process;GO:0006281//DNA repair gi|946679205|ref|XP_014433376.1|/0/PREDICTED: LOW QUALITY PROTEIN: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [Pelodiscus sinensis] 75317 3628 0.083333333 0.03 -1.473931188 Down 0.152102373 Parpbp PARP1 binding protein K05229|1|2e-30|137|mmu:110312|pro-melanin-concentrating hormone GO:0044427;GO:0031981//nuclear lumen GO:0032550;GO:0003676//nucleic acid binding;GO:0003824//catalytic activity GO:0010569//regulation of double-strand break repair via homologous recombination "gi|148689520|gb|EDL21467.1|/0/mCG16776, isoform CRA_b, partial [Mus musculus]" 110542 1947 0.03 0.08 1.415037499 Up 0.152102373 Amhr2 anti-Mullerian hormone type 2 receptor K04672|1|0.0|1026|mmu:110542|anti-mullerian hormone receptor type-2 [EC:2.7.11.30] GO:0016021//integral component of membrane GO:0043169//cation binding;GO:0032550;GO:0005024//transforming growth factor beta-activated receptor activity GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0003006//developmental process involved in reproduction;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway "gi|148672036|gb|EDL03983.1|/0/anti-Mullerian hormone type 2 receptor, isoform CRA_a, partial [Mus musculus]" 23801 2538 0.026666667 0.073333333 1.459431619 Up 0.152102373 Aloxe3 arachidonate lipoxygenase 3 K18684|1|0.0|1454|mmu:23801|hydroperoxy icosatetraenoate dehydratase/isomerase [EC:4.2.1.152 5.4.4.7] - "GO:0046914//transition metal ion binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" GO:0006690//icosanoid metabolic process;GO:0006636//unsaturated fatty acid biosynthetic process gi|226874908|ref|NP_035916.2|/0/hydroperoxide isomerase ALOXE3 [Mus musculus] 66715 2121 0.083333333 0.03 -1.473931188 Down 0.152102373 Henmt1 HEN1 methyltransferase homolog 1 (Arabidopsis) - GO:0044424;GO:0044424 GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity;GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity GO:0034660//ncRNA metabolic process;GO:0016458//gene silencing;GO:0034660//ncRNA metabolic process;GO:0016458//gene silencing gi|118403306|ref|NP_001072114.1|/0/small RNA 2'-O-methyltransferase [Mus musculus] 628709 1920 0.08 0.03 -1.415037499 Down 0.152102373 Gm10324 predicted gene 10324 K09228|1|0.0|1337|mmu:628709|KRAB domain-containing zinc finger protein - - - gi|295389583|ref|NP_001171303.1|/0/zinc finger protein family member [Mus musculus] 272411 2367 0.026666667 0.076666667 1.523561956 Up 0.152102373 B3gnt6 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)" "K00739|1|0.0|780|mmu:272411|acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.147]" GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008375//acetylglucosaminyltransferase activity GO:0016266//O-glycan processing "gi|124487189|ref|NP_001074636.1|/0/acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase [Mus musculus]" 81006 2370 0.026666667 0.076666667 1.523561956 Up 0.152102373 Gpr63 G protein-coupled receptor 63 K04321|1|0.0|810|mmu:81006|G protein-coupled receptor 63 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|31542912|ref|NP_109658.2|/0/probable G-protein coupled receptor 63 [Mus musculus] 279185 2464 0.026666667 0.073333333 1.459431619 Up 0.152102373 Gm13083 predicted gene 13083 K10308|1|6e-14|82.4|myb:102259491|F-box protein 31 - - - gi|187280849|ref|NP_001119796.1|/0/novel protein similar to the preferentially expressed antigen in melanoma like (Pramel) family [Mus musculus] 21378 7979 0.026666667 0.076666667 1.523561956 Up 0.152102373 Tbrg3 transforming growth factor beta regulated gene 3 - - - - gi|148697987|gb|EDL29934.1|/4.84396e-10/mCG148039 [Mus musculus] 16365 2588 0.026666667 0.073333333 1.459431619 Up 0.152102373 Acod1 aconitate decarboxylase 1 K17724|1|0.0|946|mmu:16365|aconitate decarboxylase [EC:4.1.1.6] - GO:0016836//hydro-lyase activity GO:0002237//response to molecule of bacterial origin "gi|950650|gb|AAA74554.1|/0/immune-responsive gene 1, partial [Mus musculus domesticus]" 93759 3882.44 2.87 2.7 -0.08809133 Down 0.152083568 Sirt1 sirtuin 1 K11411|1|0.0|1134|mmu:93759|NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-] - - - - 237400 3269 2.876666667 2.71 -0.086105207 Down 0.152083568 Mex3d mex3 RNA binding family member D K15686|1|0.0|1016|mmu:237400|RNA-binding protein MEX3 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0003723//RNA binding GO:0050789 gi|145651818|ref|NP_941017.2|/0/RNA-binding protein MEX3D [Mus musculus] 243612 1321 2.683333333 2.516666667 -0.092512139 Down 0.152083568 Ssu2 ssu-2 homolog (C. elegans) K05197|1|5e-27|124|sko:100374605|glutamate receptor 1 GO:0044424 GO:0005515//protein binding - gi|568941841|ref|XP_006506173.1|/0/PREDICTED: protein SSUH2 homolog isoform X4 [Mus musculus] 73754 2267 2.736666667 2.566666667 -0.092523776 Down 0.152083568 Thap1 "THAP domain containing, apoptosis associated protein 1" K09228|1|3e-12|76.6|gja:107120690|KRAB domain-containing zinc finger protein;K16855|4|2e-09|67.4|api:100166838|U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64] GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0003677//DNA binding "GO:0000278//mitotic cell cycle;GO:0006351//transcription, DNA-templated;GO:0050673//epithelial cell proliferation" gi|40068502|ref|NP_950243.1|/4.31602e-101/THAP domain-containing protein 1 [Mus musculus] 75625 1398 2.703333333 2.873333333 0.087985955 Up 0.152083568 Mageh1 "melanoma antigen, family H, 1" K19482|1|2e-25|119|rno:308690|necdin;K12464|2|4e-25|118|tup:102484167|melanoma-associated antigen D1 GO:0044424 - GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|625211440|ref|XP_007646521.1|/8.43751e-118/PREDICTED: melanoma-associated antigen H1 isoform X1 [Cricetulus griseus] 71330 3949 2.953333333 2.78 -0.087259315 Down 0.152083568 Rcbtb1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 K11494|1|0.0|1066|mmu:71330|RCC1 and BTB domain-containing protein GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" gi|169808411|ref|NP_082040.2|/0/RCC1 and BTB domain-containing protein 1 [Mus musculus] 211922 6366.03 2.92 2.746666667 -0.088286532 Down 0.152083568 Dennd6a DENN/MADD domain containing 6A K17654|1|5e-29|132|tsp:Tsp_05738|mitochondrial ribonuclease P protein 1 [EC:2.1.1.-] GO:0005768//endosome;GO:0005768//endosome;GO:0005768//endosome;GO:0005768//endosome GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0033634//positive regulation of cell-cell adhesion mediated by integrin;GO:0033634//positive regulation of cell-cell adhesion mediated by integrin;GO:0033634//positive regulation of cell-cell adhesion mediated by integrin;GO:0033634//positive regulation of cell-cell adhesion mediated by integrin gi|47847482|dbj|BAD21413.1|/0/mFLJ00229 protein [Mus musculus] 320213 6352 2.596666667 2.77 0.093225149 Up 0.152083568 Senp5 SUMO/sentrin specific peptidase 5 K08594|1|0.0|1503|mmu:320213|sentrin-specific protease 5 [EC:3.4.22.68] - - - - 218639 3376 2.686666667 2.516666667 -0.094303194 Down 0.152083568 Arl15 ADP-ribosylation factor-like 15 K17201|1|7e-106|388|mmu:218639|ADP-ribosylation factor-like protein 15 GO:0044464 GO:0032550 GO:0035556//intracellular signal transduction "gi|148686435|gb|EDL18382.1|/5.99683e-113/ADP-ribosylation factor-like 15, isoform CRA_a, partial [Mus musculus]" 268301 4513 0.43 0.353333333 -0.283306801 Down 0.152045959 Sowahc sosondowah ankyrin repeat domain family member C K06272|1|1e-09|68.9|api:100163230|integrin-linked kinase [EC:2.7.11.1] - - - gi|187173282|ref|NP_766527.3|/0/ankyrin repeat domain-containing protein SOWAHC [Mus musculus] 19712 4266 0.47 0.386666667 -0.281570357 Down 0.152045959 Rest RE1-silencing transcription factor K09222|1|0.0|1709|mmu:19712|RE1-silencing transcription factor - - - - 381822 582 0.36 0.436666667 0.278535499 Up 0.152045959 Lockd lncRNA downstream of Cdkn1b - - - - - 99982 3030 10.16333333 10.55 0.053869349 Up 0.152017752 Kdm1a lysine (K)-specific demethylase 1A K11450|1|0.0|1400|mmu:99982|lysine-specific histone demethylase 1A [EC:1.-.-.-] - - - gi|37360004|dbj|BAC97980.1|/0/mKIAA0601 protein [Mus musculus] 30930 3033.26 25.82 26.60333333 0.043118023 Up 0.151942533 Vps26a VPS26 retromer complex component A K18466|1|0.0|656|mmu:30930|vacuolar protein sorting-associated protein 26 GO:0012505//endomembrane system;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0022892//substrate-specific transporter activity GO:0044765//single-organism transport;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport;GO:0044765//single-organism transport;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport gi|164518904|ref|NP_001106826.1|/0/vacuolar protein sorting-associated protein 26A isoform b [Mus musculus] 13120 1871 26.62666667 25.84666667 -0.042893598 Down 0.151942533 Cyp4b1 "cytochrome P450, family 4, subfamily b, polypeptide 1" "K07426|1|0.0|1022|mmu:13120|cytochrome P450, family 4, subfamily B, polypeptide 1 [EC:1.14.14.1]" GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0042493//response to drug;GO:0042537//benzene-containing compound metabolic process;GO:0044710 gi|6681123|ref|NP_031849.1|/0/cytochrome P450 4B1 [Mus musculus] 17301 2619 0.283333333 0.213333333 -0.409390936 Down 0.151923728 Foxd2 forkhead box D2 K09397|1|2e-66|256|mmu:17301|forkhead box protein D - - - - 70821 2334 0.21 0.276666667 0.397759508 Up 0.151923728 4921507P07Rik RIKEN cDNA 4921507P07 gene - - - - "gi|148666207|gb|EDK98623.1|/0/RIKEN cDNA 4921507P07, isoform CRA_a, partial [Mus musculus]" 109267 2728 0.27 0.203333333 -0.409112665 Down 0.151923728 Ssc4d "scavenger receptor cysteine rich family, 4 domains" K13912|1|2e-136|489|cfa:486922|deleted in malignant brain tumors 1 protein - - - gi|237858578|ref|NP_001153838.1|/0/scavenger receptor cysteine-rich domain-containing group B protein precursor [Mus musculus] 327812 3204 0.226666667 0.3 0.404390255 Up 0.151923728 Gm15663 predicted gene 15663 - - - - - 22700 4079 0.286666667 0.216666667 -0.403896942 Down 0.151923728 Zfp40 zinc finger protein 40 K09228|1|0.0|1721|mmu:22700|KRAB domain-containing zinc finger protein - - - gi|113374192|ref|NP_033581.2|/0/zinc finger protein 40 [Mus musculus] 229841 7813 0.093333333 0.15 0.684498174 Up 0.151904923 Cenpe centromere protein E K11498|1|0.0|4435|mmu:229841|centromeric protein E GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0000777//condensed chromosome kinetochore GO:0032550;GO:0003774//motor activity;GO:0019900//kinase binding GO:0001934//positive regulation of protein phosphorylation;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0006928//movement of cell or subcellular component;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0032502//developmental process gi|115648101|ref|NP_776123.3|/0/centromere-associated protein E [Mus musculus] 621677 3314 0.15 0.093333333 -0.684498174 Down 0.151904923 Gm6249 predicted gene 6249 - - - - "gi|148685868|gb|EDL17815.1|/1.12202e-63/mCG144669, partial [Mus musculus]" 396184 5876 0.093333333 0.15 0.684498174 Up 0.151904923 Flrt1 fibronectin leucine rich transmembrane protein 1 K16362|1|0.0|1194|mmu:396184|leucine-rich repeat transmembrane protein FLRT - - - gi|41351537|ref|NP_958813.1|/0/leucine-rich repeat transmembrane protein FLRT1 precursor [Mus musculus] 226182 3258 1.326666667 1.203333333 -0.140769594 Down 0.151876716 Taf5 TATA-box binding protein associated factor 5 K03130|1|0.0|1285|mmu:226182|transcription initiation factor TFIID subunit 5 GO:0005856//cytoskeleton;GO:0005667//transcription factor complex GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0008080//N-acetyltransferase activity;GO:0005515//protein binding GO:0016570//histone modification;GO:0006366//transcription from RNA polymerase II promoter "gi|148710078|gb|EDL42024.1|/0/TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, partial [Mus musculus]" 19360 5153 1.286666667 1.17 -0.137129817 Down 0.151876716 Rad50 RAD50 double strand break repair protein K10866|1|0.0|2460|mmu:19360|DNA repair protein RAD50 [EC:3.6.-.-] "GO:0000781//chromosome, telomeric region;GO:0000785//chromatin;GO:0043234//protein complex;GO:0000228//nuclear chromosome;GO:0044444//cytoplasmic part" GO:0046914//transition metal ion binding;GO:0032550;GO:0005515//protein binding;GO:0004527//exonuclease activity;GO:0003676//nucleic acid binding;GO:0004520//endodeoxyribonuclease activity;GO:0003678//DNA helicase activity GO:0001934//positive regulation of protein phosphorylation;GO:0000018//regulation of DNA recombination;GO:0007127//meiosis I;GO:0043549//regulation of kinase activity;GO:0051259//protein oligomerization;GO:0006278//RNA-dependent DNA biosynthetic process;GO:0032392//DNA geometric change;GO:0006281//DNA repair gi|153945822|ref|NP_033038.2|/0/DNA repair protein RAD50 [Mus musculus] 493800 1468 1.363333333 1.24 -0.136798222 Down 0.151876716 9330162012Rik cDNA RIKEN 9330162012 gene K00139|1|2e-26|122|mmu:214579|succinate-semialdehyde dehydrogenase [EC:1.2.1.24] GO:0043231//intracellular membrane-bounded organelle "GO:0043168//anion binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding" GO:0006644//phospholipid metabolic process;GO:0022900//electron transport chain;GO:0006631//fatty acid metabolic process;GO:0043648//dicarboxylic acid metabolic process;GO:0019318//hexose metabolic process;GO:0042133//neurotransmitter metabolic process;GO:0006790//sulfur compound metabolic process;GO:0051260//protein homooligomerization;GO:0009064//glutamine family amino acid metabolic process;GO:0006677//glycosylceramide metabolic process;GO:0007399//nervous system development;GO:0009063//cellular amino acid catabolic process "gi|27369748|ref|NP_766120.1|/1.6943e-25/succinate-semialdehyde dehydrogenase, mitochondrial precursor [Mus musculus]" 18190 6677 1.15 1.266666667 0.139403057 Up 0.151876716 Nrxn2 neurexin II K07377|1|0.0|2627|mmu:18190|neurexin GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0005515//protein binding;GO:0016247//channel regulator activity;GO:0005488//binding GO:0001505//regulation of neurotransmitter levels;GO:0001941//postsynaptic membrane organization;GO:0007399//nervous system development;GO:0022610;GO:0072657//protein localization to membrane;GO:0001505//regulation of neurotransmitter levels;GO:0007399//nervous system development gi|62243518|ref|NP_064649.2|/0/neurexin-2-beta isoform 2 precursor [Mus musculus] 319996 3987.53 3.56 3.366666667 -0.080556354 Down 0.151707473 Casc4 cancer susceptibility candidate 4 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|329663856|ref|NP_001192298.1|/0/protein CASC4 isoform 3 [Mus musculus] 65967 2679 3.48 3.666666667 0.075381812 Up 0.151707473 Eefsec "eukaryotic elongation factor, selenocysteine-tRNA-specific" K03833|1|0.0|1065|mmu:65967|selenocysteine-specific elongation factor GO:0043231//intracellular membrane-bounded organelle "GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008135//translation factor activity, RNA binding" GO:0006451//translational readthrough gi|12746442|ref|NP_075547.1|/0/selenocysteine-specific elongation factor [Mus musculus] 21841 4477 3.456666667 3.27 -0.080090853 Down 0.151707473 Tia1 cytotoxic granule-associated RNA binding protein 1 K13201|1|4e-136|489|rno:312510|nucleolysin TIA-1/TIAR GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule GO:0003723//RNA binding;GO:0036094//small molecule binding;GO:0003723//RNA binding;GO:0036094//small molecule binding;GO:0003723//RNA binding "GO:0006412//translation;GO:0012501//programmed cell death;GO:0010558;GO:0000398//mRNA splicing, via spliceosome;GO:0006412//translation;GO:0012501//programmed cell death;GO:0010558;GO:0000398//mRNA splicing, via spliceosome;GO:0006412//translation;GO:0012501//programmed cell death;GO:0010558;GO:0000398//mRNA splicing, via spliceosome" "gi|148666753|gb|EDK99169.1|/2.32293e-162/cytotoxic granule-associated RNA binding protein 1, isoform CRA_c, partial [Mus musculus]" 74769 4854 3.513333333 3.703333333 0.07598395 Up 0.151707473 Pik3cb "phosphatidylinositol 3-kinase, catalytic, beta polypeptide" "K00922|1|0.0|2072|mmu:74769|phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]" GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0005903//brush border;GO:0044444//cytoplasmic part GO:0032550;GO:0005515//protein binding;GO:0052813//phosphatidylinositol bisphosphate kinase activity;GO:0052742 GO:0007160//cell-matrix adhesion;GO:0048017//inositol lipid-mediated signaling;GO:0016337//single organismal cell-cell adhesion;GO:0016192//vesicle-mediated transport;GO:0009790//embryo development;GO:0006661//phosphatidylinositol biosynthetic process;GO:0001775//cell activation;GO:0044248;GO:0006875//cellular metal ion homeostasis "gi|326327751|pdb|2Y3A|A/0/Chain A, Crystal Structure Of P110beta In Complex With Icsh2 Of P85beta And The Drug Gdc-0941" 17847 12200 3.446666667 3.633333333 0.076091949 Up 0.151707473 Usp34 ubiquitin specific peptidase 34 K11853|1|0.0|6740|mmu:17847|ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12] - GO:0005488//binding;GO:0016790//thiolester hydrolase activity;GO:0004175//endopeptidase activity;GO:0019783//ubiquitin-like protein-specific protease activity GO:0030177//positive regulation of Wnt signaling pathway;GO:0019941//modification-dependent protein catabolic process;GO:0016579//protein deubiquitination gi|357527386|ref|NP_001177330.2|/0/ubiquitin carboxyl-terminal hydrolase 34 [Mus musculus] 93709 4537 0.61 0.523333333 -0.221079089 Down 0.151679266 Pcdhga1 "protocadherin gamma subfamily A, 1" K16495|1|0.0|1701|mmu:93709|protocadherin gamma subfamily A GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|18087753|ref|NP_291062.1|/0/protocadherin gamma-A1 precursor [Mus musculus] 26447 2482 0.54 0.63 0.222392421 Up 0.151679266 Poli "polymerase (DNA directed), iota" K03510|1|0.0|1320|mmu:26447|DNA polymerase iota [EC:2.7.7.7] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003677//DNA binding;GO:0034061//DNA polymerase activity;GO:0043169//cation binding;GO:0003677//DNA binding;GO:0034061//DNA polymerase activity;GO:0043169//cation binding;GO:0003677//DNA binding;GO:0034061//DNA polymerase activity;GO:0043169//cation binding;GO:0003677//DNA binding;GO:0034061//DNA polymerase activity GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress gi|5739300|gb|AAD50424.1|AF151691_1/0/DNA polymerase iota [Mus musculus] 67784 6913 29.79666667 29.03333333 -0.037440728 Down 0.151613449 Plxnd1 plexin D1 K06822|1|0.0|3678|mmu:67784|plexin D GO:0016021//integral component of membrane;GO:0044464 GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity GO:0016477//cell migration;GO:0001525//angiogenesis;GO:0060445//branching involved in salivary gland morphogenesis;GO:0006935//chemotaxis;GO:0007399//nervous system development;GO:0007166//cell surface receptor signaling pathway gi|153792704|ref|NP_080652.2|/0/plexin-D1 precursor [Mus musculus] 67434 5825.67 6.633333333 6.913333333 0.059647463 Up 0.151604047 Ankrd33b ankyrin repeat domain 33B K12460|1|1e-13|83.2|gga:421924|ankyrin repeat-rich membrane spanning protein - GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - gi|256574786|ref|NP_001157913.1|/0/ankyrin repeat domain-containing protein 33B isoform 3 [Mus musculus] 15975 7025 7.276666667 7 -0.055922802 Down 0.151604047 Ifnar1 interferon (alpha and beta) receptor 1 K05130|1|0.0|1135|mmu:15975|interferon receptor 1 GO:0031224//intrinsic component of membrane GO:0004896//cytokine receptor activity GO:0032606//type I interferon production;GO:0046649//lymphocyte activation;GO:0007166//cell surface receptor signaling pathway;GO:0002252;GO:0001819//positive regulation of cytokine production "gi|148671880|gb|EDL03827.1|/0/interferon (alpha and beta) receptor 1, isoform CRA_c, partial [Mus musculus]" 66822 2008 7.046666667 7.33 0.056872227 Up 0.151604047 Fbxo25 F-box protein 25 K10305|1|0.0|722|mmu:66822|F-box protein 25/32 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0032446//protein modification by small protein conjugation gi|13385252|ref|NP_080061.1|/0/F-box only protein 25 [Mus musculus] 244049 5810 0.09 0.036666667 -1.295455884 Down 0.151510023 Mctp2 "multiple C2 domains, transmembrane 2" K20045|1|3e-13|81.6|acs:100553623|intersectin GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding;GO:0005543//phospholipid binding GO:0019932//second-messenger-mediated signaling gi|85701536|ref|NP_001019874.1|/0/multiple C2 and transmembrane domain-containing protein 2 [Mus musculus] 14160 4711 0.09 0.036666667 -1.295455884 Down 0.151510023 Lgr5 leucine rich repeat containing G protein coupled receptor 5 K04308|1|0.0|1631|mmu:14160|leucine-rich repeat-containing G protein-coupled receptor 5 GO:0031224//intrinsic component of membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0043583//ear development gi|110624772|ref|NP_034325.2|/0/leucine-rich repeat-containing G-protein coupled receptor 5 precursor [Mus musculus] 111970 2793 0.086666667 0.036666667 -1.2410081 Down 0.151510023 Dlx1as "distal-less homeobox 1, antisense" K09314|1|2e-31|140|myb:102261411|homeobox protein DLX1/4/6 - - - - 66733 3822 0.086666667 0.036666667 -1.2410081 Down 0.151510023 Kcng4 "potassium voltage-gated channel, subfamily G, member 4" K04903|1|0.0|876|mmu:66733|potassium voltage-gated channel subfamily G member 4 - - - - 110877 3118 0.036666667 0.09 1.295455884 Up 0.151510023 Slc18a1 "solute carrier family 18 (vesicular monoamine), member 1" "K08155|1|0.0|926|mmu:110877|MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2" GO:0031224//intrinsic component of membrane;GO:0012506//vesicle membrane GO:0005275//amine transmembrane transporter activity;GO:0005515//protein binding GO:0001504//neurotransmitter uptake;GO:0043271//negative regulation of ion transport;GO:0014046;GO:0042493//response to drug;GO:0010226//response to lithium ion gi|23346439|ref|NP_694694.1|/0/chromaffin granule amine transporter [Mus musculus] 76815 2029 0.04 0.093333333 1.222392421 Up 0.151510023 Calcoco2 calcium binding and coiled-coil domain 2 "K09228|1|2e-48|196|mmu:105245687|KRAB domain-containing zinc finger protein;K10591|2|6e-08|62.0|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26];K01106|3|3e-06|56.2|spu:575498|inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56]" GO:0043232;GO:0016604//nuclear body;GO:0044444//cytoplasmic part GO:0042802//identical protein binding GO:0034097//response to cytokine gi|568976332|ref|XP_006534523.1|/3.17796e-108/PREDICTED: calcium-binding and coiled-coil domain-containing protein 2 isoform X1 [Mus musculus] 110058 1623 0.246666667 0.32 0.375509135 Up 0.151425401 Syt17 synaptotagmin XVII K19915|1|0.0|827|mmu:110058|synaptotagmin-17 GO:0030136//clathrin-coated vesicle - GO:0051234//establishment of localization gi|20149722|ref|NP_619590.1|/0/synaptotagmin-17 [Mus musculus] 382207 4884 0.3 0.23 -0.38332864 Down 0.151425401 Jade3 jade family PHD finger 3 K11347|1|0.0|643|ssc:100516328|protein Jade-1 GO:0043234//protein complex;GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0043967//histone H4 acetylation;GO:0043967//histone H4 acetylation gi|576067801|ref|NP_955021.2|/0/protein Jade-3 isoform 1 [Mus musculus] 231570 6756 0.223333333 0.29 0.376854305 Up 0.151425401 A830010M20Rik RIKEN cDNA A830010M20 gene K10480|1|2e-143|513|rno:100364240|BTB/POZ domain-containing protein 8 - - - gi|270483724|ref|NP_001162029.1|/0/uncharacterized protein KIAA1107 isoform 2 [Mus musculus] 72661 841.14 0.47 0.39 -0.269186633 Down 0.151425401 Serp2 stress-associated endoplasmic reticulum protein family member 2 - GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0045184//establishment of protein localization;GO:0045184//establishment of protein localization gi|568988887|ref|XP_006519663.1|/2.91408e-36/PREDICTED: stress-associated endoplasmic reticulum protein 2 isoform X2 [Mus musculus] 74107 2385 0.23 0.3 0.38332864 Up 0.151425401 Cep55 centrosomal protein 55 K16456|1|0.0|782|mmu:74107|centrosomal protein CEP55 GO:0044421;GO:0032155;GO:0005813//centrosome;GO:0044421;GO:0032155;GO:0005813//centrosome;GO:0044421;GO:0032155;GO:0005813//centrosome GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0000087//mitotic M phase;GO:0000087//mitotic M phase;GO:0000087//mitotic M phase "gi|148709852|gb|EDL41798.1|/0/centrosomal protein 55, isoform CRA_d, partial [Mus musculus]" 217169 4755 0.493333333 0.41 -0.26693886 Down 0.151425401 Tns4 tensin 4 K18080|1|0.0|1292|mmu:217169|tensin - - - - 240186 3209 1.99 2.14 0.104842366 Up 0.151406597 Zfp438 zinc finger protein 438 K09228|1|1e-12|78.6|bfo:BRAFLDRAFT_119633|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated" "gi|148691096|gb|EDL23043.1|/0/zinc finger protein 438, isoform CRA_a, partial [Mus musculus]" 20351 3046 2.193333333 2.343333333 0.095437105 Up 0.151406597 Sema4a "sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A" K06521|1|0.0|1443|mmu:20351|semaphorin 4 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0001525//angiogenesis;GO:0002286//T cell activation involved in immune response;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0022604//regulation of cell morphogenesis;GO:0030334//regulation of cell migration;GO:0042088//T-helper 1 type immune response;GO:0007166//cell surface receptor signaling pathway;GO:0001525//angiogenesis;GO:0002286//T cell activation involved in immune response;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0022604//regulation of cell morphogenesis;GO:0006935//chemotaxis;GO:0030334//regulation of cell migration;GO:0042088//T-helper 1 type immune response;GO:0007166//cell surface receptor signaling pathway;GO:0001525//angiogenesis;GO:0002286//T cell activation involved in immune response;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0022604//regulation of cell morphogenesis;GO:0006935//chemotaxis;GO:0030334//regulation of cell migration;GO:0042088//T-helper 1 type immune response;GO:0007166//cell surface receptor signaling pathway;GO:0001525//angiogenesis;GO:0002286//T cell activation involved in immune response;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0022604//regulation of cell morphogenesis;GO:0006935//chemotaxis;GO:0030334//regulation of cell migration;GO:0042088//T-helper 1 type immune response;GO:0007166//cell surface receptor signaling pathway gi|568922186|ref|XP_006501251.1|/0/PREDICTED: semaphorin-4A isoform X3 [Mus musculus] 100040736 2876 0.153333333 0.096666667 -0.665580961 Down 0.151368987 Foxd2os "forkhead box D2, opposite strand" - - - - "gi|148698720|gb|EDL30667.1|/3.19658e-35/mCG1049272, isoform CRA_a, partial [Mus musculus]" 18072 3353 0.1 0.156666667 0.647698256 Up 0.151368987 Nhlh2 nescient helix loop helix 2 K09075|1|2e-37|160|hgl:106007536|nescient helix-loop-helix protein GO:0043234//protein complex GO:0001085//RNA polymerase II transcription factor binding GO:0007618//mating;GO:0044093;GO:0007399//nervous system development;GO:0044702//single organism reproductive process;GO:0006366//transcription from RNA polymerase II promoter gi|512983752|ref|XP_004853851.1|/2.02165e-36/PREDICTED: helix-loop-helix protein 2 isoform X1 [Heterocephalus glaber] 20460 5094 0.153333333 0.096666667 -0.665580961 Down 0.151368987 Stil Scl/Tal1 interrupting locus K16724|1|0.0|1040|mmu:20460|SCL-interrupting locus protein GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center - GO:0014020;GO:0006915//apoptotic process;GO:0003143//embryonic heart tube morphogenesis;GO:0007420//brain development;GO:0040007//growth;GO:0007166//cell surface receptor signaling pathway;GO:0009855//determination of bilateral symmetry;GO:0048568//embryonic organ development;GO:0014020;GO:0006915//apoptotic process;GO:0003143//embryonic heart tube morphogenesis;GO:0007420//brain development;GO:0040007//growth;GO:0007166//cell surface receptor signaling pathway;GO:0009855//determination of bilateral symmetry;GO:0048568//embryonic organ development;GO:0014020;GO:0006915//apoptotic process;GO:0003143//embryonic heart tube morphogenesis;GO:0007420//brain development;GO:0040007//growth;GO:0007166//cell surface receptor signaling pathway;GO:0009855//determination of bilateral symmetry;GO:0048568//embryonic organ development;GO:0014020;GO:0006915//apoptotic process;GO:0003143//embryonic heart tube morphogenesis;GO:0007420//brain development;GO:0040007//growth;GO:0007166//cell surface receptor signaling pathway;GO:0009855//determination of bilateral symmetry;GO:0048568//embryonic organ development gi|164698492|ref|NP_033211.2|/0/SCL-interrupting locus protein homolog isoform 1 [Mus musculus] 75507 1395 0.106666667 0.17 0.672425342 Up 0.151368987 Pou5f2 "POU domain class 5, transcription factor 2" "K09367|1|9e-74|280|ngi:103739849|POU domain transcription factor, class 5" - - - - 216820 1556.43 10.03333333 10.41333333 0.053630966 Up 0.151368987 Dhrs7b dehydrogenase/reductase (SDR family) member 7B K11166|1|5e-170|600|mmu:216820|dehydrogenase/reductase SDR family member 7B [EC:1.1.-.-] - - - - 79566 3024 10.11666667 10.49666667 0.053197241 Up 0.151368987 Sh3bp5l SH3 binding domain protein 5 like K20478|1|4e-28|129|hro:HELRODRAFT_191501|golgin subfamily B member 1 - - - gi|74201397|dbj|BAE26141.1|/1.23581e-149/unnamed protein product [Mus musculus] 109151 11517 1.08 0.966666667 -0.159940913 Down 0.151265561 Chd9 chromodomain helicase DNA binding protein 9 K14438|1|0.0|4170|mmu:109151|chromodomain-helicase-DNA-binding protein 9 [EC:3.6.4.12] - - - - 69713 478 24.81333333 24.07 -0.043879413 Down 0.151265561 Pin4 "protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)" K09579|1|5e-55|214|rno:684441|peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 [EC:5.2.1.8] GO:0015630//microtubule cytoskeleton;GO:0031981//nuclear lumen;GO:0044429;GO:0030529//intracellular ribonucleoprotein complex GO:0043566//structure-specific DNA binding GO:0044238//primary metabolic process;GO:0044260;GO:0042254//ribosome biogenesis gi|795540714|ref|XP_011904346.1|/2.54413e-54/PREDICTED: peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 [Cercocebus atys] 12571 11534 0.96 1.073333333 0.160991877 Up 0.151265561 Cdk6 cyclin-dependent kinase 6 K02091|1|0.0|654|mmu:12571|cyclin-dependent kinase 6 [EC:2.7.11.22] - - - - 214791 3363.13 1.08 0.966666667 -0.159940913 Down 0.151265561 Sertad4 SERTA domain containing 4 - - - - "gi|148681014|gb|EDL12961.1|/1.15121e-179/SERTA domain containing 4, isoform CRA_a, partial [Mus musculus]" 227707 1345 27.20333333 27.94 0.038548579 Up 0.151265561 BC005624 cDNA sequence BC005624 "K11703|1|6e-35|150|sko:100378316|collagen beta-1,O-galactosyltransferase [EC:2.4.1.50];K11643|2|6e-06|54.7|crg:105345699|chromodomain-helicase-DNA-binding protein 4 [EC:3.6.4.12]" - - - gi|21450249|ref|NP_659134.1|/3.56186e-152/uncharacterized protein C9orf78 homolog [Mus musculus] 319520 2427 1.073333333 0.96 -0.160991877 Down 0.151265561 Dusp4 dual specificity phosphatase 4 K04459|1|0.0|731|mmu:319520|dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] - - - gi|28892737|ref|NP_795907.1|/0/dual specificity protein phosphatase 4 [Mus musculus] 68027 1696 0.413333333 0.496666667 0.26497221 Up 0.151171537 Tmem178 transmembrane protein 178 - - - - "gi|148706586|gb|EDL38533.1|/1.15998e-145/RIKEN cDNA 2810417M05, partial [Mus musculus]" 75564 942 0.43 0.513333333 0.255559285 Up 0.151171537 Rsph9 radial spoke head 9 homolog (Chlamydomonas) K19757|1|5e-144|512|mmu:75564|radial spoke head protein 9 GO:0005929//cilium;GO:0043232;GO:0005930//axoneme - GO:0007018//microtubule-based movement gi|21312974|ref|NP_083614.1|/3.86333e-143/radial spoke head protein 9 homolog [Mus musculus] 233071 4356 0.39 0.466666667 0.258918297 Up 0.151171537 Arhgap33 Rho GTPase activating protein 33 K17933|1|0.0|2031|mmu:233071|Rho GTPase-activating protein 33 GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0044424;GO:0016020//membrane;GO:0044424 GO:0005543//phospholipid binding;GO:0005543//phospholipid binding;GO:0005543//phospholipid binding GO:0045184//establishment of protein localization;GO:0007154//cell communication;GO:0045184//establishment of protein localization;GO:0007154//cell communication;GO:0045184//establishment of protein localization;GO:0007154//cell communication gi|30142699|ref|NP_839983.1|/0/rho GTPase-activating protein 33 isoform a [Mus musculus] 229004 4050 4.493333333 4.276666667 -0.071299326 Down 0.15110572 Gmeb2 glucocorticoid modulatory element binding protein 2 - GO:0031981//nuclear lumen GO:0043169//cation binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|37718989|ref|NP_937812.1|/0/glucocorticoid modulatory element-binding protein 2 [Mus musculus] 226351 2830 4.41 4.63 0.070233538 Up 0.15110572 Tmem185b transmembrane protein 185B "K00547|1|5e-25|119|smm:Smp_147610|homocysteine S-methyltransferase [EC:2.1.1.10];K18207|2|4e-06|56.6|phu:Phum_PHUM177410|protein O-mannose beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.312]" GO:0031224//intrinsic component of membrane - - gi|22122617|ref|NP_666215.1|/0/transmembrane protein 185B [Mus musculus] 232879 2167 4.69 4.913333333 0.067114196 Up 0.15110572 Zbtb45 zinc finger and BTB domain containing 45 K10516|1|0.0|788|mmu:232879|zinc finger and BTB domain-containing protein 45 - - - gi|85701534|ref|NP_001019870.1|/0/zinc finger and BTB domain-containing protein 45 [Mus musculus] 116847 3602 26.63 27.36333333 0.039191558 Up 0.151096318 Prelp proline arginine-rich end leucine-rich repeat K08125|1|5e-176|621|mmu:116847|proline arginine-rich end leucine-rich repeat protein GO:0031012//extracellular matrix GO:0005539//glycosaminoglycan binding GO:0007568//aging gi|568908031|ref|XP_006529146.1|/1.15127e-178/PREDICTED: prolargin isoform X2 [Mus musculus] 54451 2560 23.68666667 22.96 -0.044952546 Down 0.151096318 Cpsf3 cleavage and polyadenylation specificity factor 3 K14403|1|0.0|1375|mmu:54451|cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] GO:0005849//mRNA cleavage factor complex GO:0004527//exonuclease activity;GO:0004519//endonuclease activity;GO:0043169//cation binding;GO:0003723//RNA binding GO:0008334//histone mRNA metabolic process;GO:0031124//mRNA 3'-end processing "gi|148702078|gb|EDL34025.1|/0/cleavage and polyadenylation specificity factor 3, isoform CRA_b, partial [Mus musculus]" 217154 3049 0.04 0.09 1.169925001 Up 0.151068111 Stac2 SH3 and cysteine rich domain 2 K20045|1|1e-08|65.1|loa:LOAG_06191|intersectin;K06114|2|4e-08|63.5|nvi:100116996|spectrin alpha;K05730|4|3e-07|60.5|mde:101896721|guanine nucleotide exchange factor VAV;K04364|5|4e-07|60.1|mde:101896778|growth factor receptor-binding protein 2 - GO:0043169//cation binding GO:0007165//signal transduction gi|674072635|ref|XP_008843510.1|/0/PREDICTED: SH3 and cysteine-rich domain-containing protein 2 isoform X2 [Nannospalax galili] 238205 4417 0.083333333 0.036666667 -1.184424571 Down 0.151068111 Lrfn5 leucine rich repeat and fibronectin type III domain containing 5 K16358|1|0.0|1259|mcf:102139536|leucine-rich repeat and fibronectin type-III domain-containing protein 5 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148704717|gb|EDL36664.1|/0/leucine rich repeat and fibronectin type III domain containing 5, isoform CRA_a, partial [Mus musculus]" 13004 7184 0.036666667 0.083333333 1.184424571 Up 0.151068111 Ncan neurocan K06794|1|0.0|2318|mmu:13004|neurocan core protein GO:0016020//membrane;GO:0044431//Golgi apparatus part;GO:0005764//lysosome GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding GO:0006027//glycosaminoglycan catabolic process;GO:0022610;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0050807//regulation of synapse organization;GO:0044238//primary metabolic process;GO:0006935//chemotaxis gi|40789268|ref|NP_031815.2|/0/neurocan core protein precursor [Mus musculus] 217653 4038 0.083333333 0.036666667 -1.184424571 Down 0.151068111 Mis18bp1 MIS18 binding protein 1 - GO:0043232;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0000087//mitotic M phase "gi|148704698|gb|EDL36645.1|/0/expressed sequence C79407, partial [Mus musculus]" 75209 4252 0.036666667 0.083333333 1.184424571 Up 0.151068111 Sv2c synaptic vesicle glycoprotein 2c "K06258|1|0.0|1399|mmu:75209|MFS transporter, VNT family, synaptic vesicle glycoprotein 2" GO:0008021//synaptic vesicle;GO:0031224//intrinsic component of membrane GO:0005215//transporter activity - gi|50510769|dbj|BAD32370.1|/0/mKIAA1054 protein [Mus musculus] 27375 2941 0.036666667 0.083333333 1.184424571 Up 0.151068111 Tjp3 tight junction protein 3 K06097|1|0.0|1557|mmu:27375|tight junction protein 3 GO:0043296//apical junction complex;GO:0044459;GO:0043296//apical junction complex;GO:0044459 - GO:1901990//regulation of mitotic cell cycle phase transition;GO:1901990//regulation of mitotic cell cycle phase transition gi|530788242|ref|NP_001269025.1|/0/tight junction protein ZO-3 isoform 1 [Mus musculus] 17221 1887 0.106666667 0.166666667 0.64385619 Up 0.151049306 Cd46 "CD46 antigen, complement regulatory protein" K04007|1|0.0|642|mmu:17221|membrane cofactor protein - - - - 114642 4710 0.113333333 0.176666667 0.640457613 Up 0.151049306 Brdt "bromodomain, testis-specific" K11724|1|0.0|1507|mmu:114642|bromodomain testis-specific protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0042393//histone binding;GO:0042393//histone binding "GO:0016568//chromatin modification;GO:0048869//cellular developmental process;GO:0008380//RNA splicing;GO:0007127//meiosis I;GO:0048232//male gamete generation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0016568//chromatin modification;GO:0048869//cellular developmental process;GO:0008380//RNA splicing;GO:0007127//meiosis I;GO:0048232//male gamete generation;GO:0045893//positive regulation of transcription, DNA-templated" gi|120431736|ref|NP_473395.2|/0/bromodomain testis-specific protein isoform A [Mus musculus] 399558 7099 0.31 0.24 -0.36923381 Down 0.150983489 Flrt2 fibronectin leucine rich transmembrane protein 2 K16362|1|0.0|1225|mmu:399558|leucine-rich repeat transmembrane protein FLRT GO:0016021//integral component of membrane;GO:0031012//extracellular matrix GO:0004871//signal transducer activity;GO:0005515//protein binding GO:0022610 gi|41462393|ref|NP_958926.1|/0/leucine-rich repeat transmembrane protein FLRT2 precursor [Mus musculus] 98870 1703 0.23 0.296666667 0.367208974 Up 0.150983489 AI182371 expressed sequence AI182371 K03994|1|1e-87|326|umr:103670372|complement component 5 - - - "gi|148676695|gb|EDL08642.1|/0/expressed sequence AI182371, isoform CRA_c, partial [Mus musculus]" 71893 2239 0.24 0.31 0.36923381 Up 0.150983489 Noxo1 NADPH oxidase organizer 1 K17934|1|0.0|715|mmu:71893|NADPH oxidase organizer 1 GO:0005887//integral component of plasma membrane GO:0008047//enzyme activator activity;GO:0005543//phospholipid binding;GO:0005515//protein binding GO:0022411;GO:0044093;GO:0072593//reactive oxygen species metabolic process "gi|148690409|gb|EDL22356.1|/0/NADPH oxidase organizer 1, isoform CRA_b, partial [Mus musculus]" 320626 2250 0.296666667 0.23 -0.367208974 Down 0.150983489 9230105E05Rik RIKEN cDNA 9230105E05 gene - - - - - 235442 4751 1.986666667 1.843333333 -0.10803285 Down 0.15094588 Rab8b "RAB8B, member RAS oncogene family" K07902|1|4e-116|422|ocu:100349093|Ras-related protein Rab-8B GO:0030666//endocytic vesicle membrane;GO:0060187//cell pole;GO:0044439 GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0019904//protein domain specific binding GO:0051458//corticotropin secretion;GO:0030030//cell projection organization;GO:0009154//purine ribonucleotide catabolic process;GO:0006625//protein targeting to peroxisome;GO:0045216//cell-cell junction organization;GO:0035556//intracellular signal transduction gi|655862514|ref|XP_002718230.2|/3.2061e-115/PREDICTED: ras-related protein Rab-8B [Oryctolagus cuniculus] 53860 3582.79 26.84333333 26.12 -0.039408936 Down 0.150936477 9-Sep septin 9 K16938|1|0.0|693|mmu:53860|septin 3/9/12 GO:0032432//actin filament bundle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0032432//actin filament bundle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0032432//actin filament bundle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0032432//actin filament bundle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0032550;GO:0032550;GO:0032550;GO:0032550 GO:0044763;GO:0051259//protein oligomerization;GO:0044763;GO:0051259//protein oligomerization;GO:0044763;GO:0051259//protein oligomerization;GO:0044763;GO:0051259//protein oligomerization gi|49022852|dbj|BAC65697.2|/0/mKIAA0991 protein [Mus musculus] 16175 1974 0.103333333 0.16 0.63076619 Up 0.150804844 Il1a interleukin 1 alpha K04383|1|1e-151|539|mmu:16175|interleukin 1 alpha GO:0044444//cytoplasmic part;GO:0044421 GO:0005126//cytokine receptor binding;GO:0046914//transition metal ion binding GO:0042094//interleukin-2 biosynthetic process;GO:0050663//cytokine secretion;GO:0019233//sensory perception of pain;GO:0043410//positive regulation of MAPK cascade;GO:0006953//acute-phase response;GO:0007254//JNK cascade;GO:0001819//positive regulation of cytokine production;GO:0010212//response to ionizing radiation;GO:0032872//regulation of stress-activated MAPK cascade;GO:0009408//response to heat;GO:0030216//keratinocyte differentiation;GO:0000302//response to reactive oxygen species;GO:0002237//response to molecule of bacterial origin;GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway;GO:0010038//response to metal ion;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0033273//response to vitamin;GO:0006694//steroid biosynthetic process;GO:0007067//mitotic nuclear division;GO:0009719 "gi|148696289|gb|EDL28236.1|/2.65682e-152/interleukin 1 alpha, isoform CRA_a, partial [Mus musculus]" 18125 9695 0.16 0.103333333 -0.63076619 Down 0.150804844 Nos1 "nitric oxide synthase 1, neuronal" "K13240|1|0.0|2838|mmu:18125|nitric-oxide synthase, brain [EC:1.14.13.39]" - - - "gi|6724321|ref|NP_032738.1|/0/nitric oxide synthase, brain [Mus musculus]" 381591 2942 0.103333333 0.16 0.63076619 Up 0.150804844 L1td1 LINE-1 type transposase domain containing 1 K19352|1|8e-10|68.9|lcm:102346445|coiled-coil and C2 domain-containing protein 2A;K13706|2|1e-06|58.2|pbi:103050372|abhydrolase domain-containing protein 14;K01196|3|9e-06|55.5|xma:102230673|glycogen debranching enzyme [EC:2.4.1.25 3.2.1.33] - - - gi|124487095|ref|NP_001074671.1|/0/LINE-1 type transposase domain-containing protein 1 [Mus musculus] 26951 2917 6.443333333 6.713333333 0.059222046 Up 0.150795442 Zw10 zw10 kinetochore protein K11578|1|0.0|1524|mmu:26951|protein transport protein DSL1/ZW10 GO:0043231//intracellular membrane-bounded organelle;GO:0005876//spindle microtubule;GO:0000776//kinetochore;GO:0031090//organelle membrane - GO:0000075//cell cycle checkpoint;GO:0000070//mitotic sister chromatid segregation;GO:0045184//establishment of protein localization;GO:0040001//establishment of mitotic spindle localization;GO:0034502//protein localization to chromosome;GO:0016482//cytosolic transport;GO:0065003;GO:0007346//regulation of mitotic cell cycle gi|22165349|ref|NP_036169.1|/0/centromere/kinetochore protein zw10 homolog [Mus musculus] 19014 4536.39 6.593333333 6.32 -0.061083462 Down 0.150795442 Med1 mediator complex subunit 1 K15144|1|0.0|1849|mmu:19014|mediator of RNA polymerase II transcription subunit 1 GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0044427 "GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0035258//steroid hormone receptor binding;GO:0010861//thyroid hormone receptor activator activity;GO:0008134//transcription factor binding;GO:0003713//transcription coactivator activity;GO:0032403//protein complex binding;GO:0019904//protein domain specific binding;GO:0003682//chromatin binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding" "GO:0030326//embryonic limb morphogenesis;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0030219//megakaryocyte differentiation;GO:0006915//apoptotic process;GO:0001701//in utero embryonic development;GO:0003006//developmental process involved in reproduction;GO:0010556;GO:0032989;GO:0043353//enucleate erythrocyte differentiation;GO:0060041//retina development in camera-type eye;GO:0010469//regulation of receptor activity;GO:0050679//positive regulation of epithelial cell proliferation;GO:0006259//DNA metabolic process;GO:0007589//body fluid secretion;GO:0042403//thyroid hormone metabolic process;GO:0035728//response to hepatocyte growth factor;GO:0000060//protein import into nucleus, translocation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0070849//response to epidermal growth factor;GO:0030182//neuron differentiation;GO:0030216//keratinocyte differentiation;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0006360//transcription from RNA polymerase I promoter;GO:0008285//negative regulation of cell proliferation;GO:0007417//central nervous system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0033598//mammary gland epithelial cell proliferation;GO:0002573//myeloid leukocyte differentiation;GO:0000165//MAPK cascade;GO:0045023//G0 to G1 transition;GO:0006694//steroid biosynthetic process" "gi|148684171|gb|EDL16118.1|/0/peroxisome proliferator activated receptor binding protein, isoform CRA_a [Mus musculus]" 52592 2566 6.486666667 6.753333333 0.058122464 Up 0.150795442 Brms1l breast cancer metastasis-suppressor 1-like K19196|1|1e-164|582|mmu:52592|breast cancer metastasis-suppressor 1 and related proteins GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated;GO:0040007//growth" "gi|148704772|gb|EDL36719.1|/7.31267e-177/mCG22342, isoform CRA_c, partial [Mus musculus]" 106572 3476 6.896666667 6.626666667 -0.057615888 Down 0.150795442 Rab31 "RAB31, member RAS oncogene family" K07891|1|7e-109|398|mmu:106572|Ras-related protein Rab-22 - - - - 104156 3847 6.66 6.933333333 0.058026945 Up 0.150795442 Etv5 ets variant 5 K15593|1|0.0|979|mmu:104156|ets translocation variant 5 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding "GO:0006351//transcription, DNA-templated;GO:0050803//regulation of synapse structure or activity;GO:0007283//spermatogenesis;GO:0008284//positive regulation of cell proliferation;GO:0001941//postsynaptic membrane organization;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0006979//response to oxidative stress;GO:0030182//neuron differentiation" "gi|148665211|gb|EDK97627.1|/0/mCG127346, isoform CRA_b, partial [Mus musculus]" 75099 3170.1 7.06 6.793333333 -0.055548538 Down 0.150795442 Lysmd4 "LysM, putative peptidoglycan-binding, domain containing 4" - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0044036;GO:0044036 gi|30424844|ref|NP_780424.1|/9.99004e-157/lysM and putative peptidoglycan-binding domain-containing protein 4 [Mus musculus] 230249 5919 26.82333333 26.11666667 -0.038517758 Down 0.150757832 AI314180 expressed sequence AI314180 K11886|1|0.0|3377|mmu:230249|proteasome component ECM29 GO:0005815//microtubule organizing center;GO:0005770//late endosome;GO:0030133//transport vesicle - GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process "gi|148670273|gb|EDL02220.1|/0/expressed sequence AI314180, isoform CRA_a, partial [Mus musculus]" 408254 2990 0.33 0.256666667 -0.362570079 Down 0.150739027 A630019I02Rik RIKEN cDNA A630019I02 gene K05185|1|7e-12|75.9|rno:65191|gamma-aminobutyric acid receptor subunit epsilon - - - - 11835 10063 0.3 0.233333333 -0.362570079 Down 0.150739027 Ar androgen receptor K08557|1|0.0|1540|mmu:11835|androgen receptor GO:0043005//neuron projection;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0016020//membrane "GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0005496//steroid binding;GO:0035258//steroid hormone receptor binding;GO:0008134//transcription factor binding;GO:0019904//protein domain specific binding;GO:0000975//regulatory region DNA binding;GO:0046914//transition metal ion binding" GO:0006461//protein complex assembly;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0006915//apoptotic process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0043434//response to peptide hormone;GO:0008406//gonad development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0043009//chordate embryonic development;GO:0048232//male gamete generation;GO:0018993//somatic sex determination;GO:0009967//positive regulation of signal transduction;GO:0008217//regulation of blood pressure;GO:0016310//phosphorylation;GO:0051128//regulation of cellular component organization;GO:0003156//regulation of organ formation;GO:0040008//regulation of growth;GO:0030539//male genitalia development;GO:0006383//transcription from RNA polymerase III promoter;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0010558;GO:0000165//MAPK cascade;GO:0060444//branching involved in mammary gland duct morphogenesis gi|7304901|ref|NP_038504.1|/0/androgen receptor [Mus musculus] 73694 2303 11.67333333 12.04666667 0.045417422 Up 0.150626199 Ndufaf7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex assembly factor 7 K18164|1|0.0|880|mmu:73694|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7 - - - - 71268 3218.99 27.64666667 26.95 -0.036820274 Down 0.150607394 Lrrfip2 leucine rich repeat (in FLII) interacting protein 2 K17785|1|5e-26|122|hgl:101700543|mitofilin;K17570|2|6e-16|89.4|smm:Smp_175460|hydrocephalus-inducing protein;K10352|3|2e-08|64.7|phi:102113819|myosin heavy chain - GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding - gi|258679524|ref|NP_001158310.1|/0/leucine-rich repeat flightless-interacting protein 2 isoform 1 [Mus musculus] 74645 2054 0.166666667 0.11 -0.59946207 Down 0.150569784 Fam46c "family with sequence similarity 46, member C" "K05742|1|4e-143|511|apla:101803574|solute carrier family 9 (sodium/hydrogen exchanger), member 1" - - - "gi|28374199|gb|AAH46309.1|/0/Fam46c protein, partial [Mus musculus]" 320827 6835 0.19 0.126666667 -0.584962501 Down 0.150569784 C530008M17Rik RIKEN cDNA C530008M17 gene K02991|1|2e-09|69.3|obi:106881151|small subunit ribosomal protein S6e;K11294|2|3e-09|68.6|dpo:Dpse_GA23518|nucleolin;K04574|4|4e-09|67.8|mgp:100550205|neurofilament heavy polypeptide;K13172|5|2e-08|65.9|oaa:100075123|serine/arginine repetitive matrix protein 2 - - - - 231583 3608 0.12 0.183333333 0.611434712 Up 0.150569784 Slc26a1 "solute carrier family 26 (sulfate transporter), member 1" "K14700|1|0.0|1309|mmu:231583|solute carrier family 26 (sulfate anion transporter), member 1" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity;GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity;GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity GO:0015698//inorganic anion transport;GO:0006835//dicarboxylic acid transport;GO:0044763;GO:0015698//inorganic anion transport;GO:0006835//dicarboxylic acid transport;GO:0044763;GO:0015698//inorganic anion transport;GO:0006835//dicarboxylic acid transport;GO:0044763 gi|893553075|ref|NP_001297620.1|/0/sulfate anion transporter 1 isoform 1 [Mus musculus] 329514 1396 0.113333333 0.17 0.584962501 Up 0.150569784 Il1bos "interleukin 1 beta, opposite strand" K09228|1|5e-10|68.2|cge:100762252|KRAB domain-containing zinc finger protein - - - - 12299 1225 0.086666667 0.04 -1.115477217 Down 0.15055098 Cacng1 "calcium channel, voltage-dependent, gamma subunit 1" K04866|1|1e-94|348|mmu:12299|voltage-dependent calcium channel gamma-1 GO:0016021//integral component of membrane GO:0005262//calcium channel activity GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport gi|74209029|dbj|BAE21242.1|/1.12488e-93/unnamed protein product [Mus musculus] 110333 2687 0.04 0.086666667 1.115477217 Up 0.15055098 Rmst rhabdomyosarcoma 2 associated transcript (non-coding RNA) "K10408|1|4e-06|56.6|lcm:102364796|dynein heavy chain, axonemal" - - - - 67749 1245 0.086666667 0.04 -1.115477217 Down 0.15055098 Mgarp mitochondria localized glutamic acid rich protein - GO:0031306//intrinsic component of mitochondrial outer membrane;GO:0031306//intrinsic component of mitochondrial outer membrane - GO:0001666//response to hypoxia;GO:0008088//axo-dendritic transport;GO:0006605//protein targeting;GO:0007005//mitochondrion organization;GO:0071375//cellular response to peptide hormone stimulus;GO:0001666//response to hypoxia;GO:0008088//axo-dendritic transport;GO:0006605//protein targeting;GO:0007005//mitochondrion organization;GO:0071375//cellular response to peptide hormone stimulus "gi|148703256|gb|EDL35203.1|/2.1903e-94/RIKEN cDNA 4930583H14, isoform CRA_a [Mus musculus]" 76415 1233 0.086666667 0.04 -1.115477217 Down 0.15055098 Fam187b "family with sequence similarity 187, member B" - GO:0031224//intrinsic component of membrane;GO:0016020//membrane;GO:0031224//intrinsic component of membrane - - gi|564297220|ref|XP_002725612.2|/3.83159e-163/PREDICTED: protein FAM187B [Rattus norvegicus] 73449 2504 0.043333333 0.096666667 1.157541277 Up 0.15055098 1700066B19Rik RIKEN cDNA 1700066B19 gene - - - - gi|85701682|ref|NP_001028340.1|/7.6016e-54/uncharacterized protein LOC73449 [Mus musculus] 100042194 2050 0.096666667 0.046666667 -1.050626073 Down 0.15055098 Gm13446 predicted gene 13446 - - - - - 100504267 3121 0.096666667 0.046666667 -1.050626073 Down 0.15055098 Trp53cor1 tumor protein p53 pathway corepressor 1 - - - - - 170947 3397 0.1 0.046666667 -1.099535674 Down 0.15055098 Myoz3 myozenin 3 - GO:0031674//I band GO:0005488//binding - gi|238550192|ref|NP_579941.2|/1.92756e-135/myozenin-3 [Mus musculus] 214403 2710 0.093333333 0.043333333 -1.106915204 Down 0.15055098 Gm4788 predicted gene 4788 K04004|1|0.0|1368|mmu:12628|complement factor H GO:0005576//extracellular region;GO:0044424;GO:0005576//extracellular region;GO:0044424;GO:0044464 GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0044699;GO:0045087//innate immune response;GO:0048583;GO:0002252;GO:0010033//response to organic substance;GO:0044699;GO:0045087//innate immune response;GO:0048583;GO:0002252;GO:0010033//response to organic substance;GO:0044699;GO:0045087//innate immune response;GO:0048583;GO:0002252 gi|237757322|ref|NP_001153775.1|/0/complement factor H-related protein C isoform 2 precursor [Mus musculus] 231760 6996 0.086666667 0.04 -1.115477217 Down 0.15055098 Rimbp2 RIMS binding protein 2 K17591|1|0.0|1891|mmu:231760|RIMS-binding protein 2 - - GO:0010921//regulation of phosphatase activity;GO:0010921//regulation of phosphatase activity gi|894216223|ref|NP_001297662.1|/0/RIMS-binding protein 2 isoform 2 [Mus musculus] 71354 2450 0.046666667 0.093333333 1 Up 0.15055098 Wdr31 WD repeat domain 31 "K16482|1|3e-18|96.7|sko:100378584|centriolar protein POC1;K16794|2|2e-17|93.6|bfo:BRAFLDRAFT_59218|platelet-activating factor acetylhydrolase IB subunit alpha;K17890|4|5e-17|92.4|xma:102219511|autophagy-related protein 16, animal type" - - - gi|12963745|ref|NP_076086.1|/0/WD repeat-containing protein 31 isoform 1 [Mus musculus] 319581 2855 0.1 0.05 -1 Down 0.15055098 Xkr5 X-linked Kx blood group related 5 K19522|1|2e-06|58.2|ccw:104686218|membrane transport protein XK - - - - 71781 2363 0.043333333 0.093333333 1.106915204 Up 0.15055098 Slc16a14 "solute carrier family 16 (monocarboxylic acid transporters), member 14" "K08190|1|0.0|1000|mmu:71781|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 14" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0051234//establishment of localization;GO:0044763 gi|41281606|ref|NP_082197.1|/0/monocarboxylate transporter 14 [Mus musculus] 100038909 2130 0.043333333 0.093333333 1.106915204 Up 0.15055098 Gm14548 predicted gene 14548 K06512|1|0.0|1285|mmu:100038909|leukocyte immunoglobulin-like receptor - - - gi|262263322|ref|NP_001160144.1|/0/predicted gene 14548 precursor [Mus musculus] 76856 1352 0.09 0.043333333 -1.054447784 Down 0.15055098 Catsper3 "cation channel, sperm associated 3" K16891|1|4e-177|623|mmu:76856|cation channel sperm-associated protein 3 GO:0030141//secretory granule;GO:0005891//voltage-gated calcium channel complex;GO:0030141//secretory granule;GO:0005891//voltage-gated calcium channel complex;GO:0030141//secretory granule;GO:0005891//voltage-gated calcium channel complex GO:0005488//binding;GO:0005261//cation channel activity;GO:0005488//binding;GO:0005261//cation channel activity;GO:0005488//binding;GO:0005261//cation channel activity GO:0048869//cellular developmental process;GO:0048870//cell motility;GO:0048232//male gamete generation;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0048869//cellular developmental process;GO:0048870//cell motility;GO:0048232//male gamete generation;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0048869//cellular developmental process;GO:0048870//cell motility;GO:0048232//male gamete generation;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport "gi|148709282|gb|EDL41228.1|/0/cation channel, sperm associated 3, isoform CRA_b, partial [Mus musculus]" 17535 5779.99 1.596666667 1.73 0.115708883 Up 0.150541577 Mre11a "MRE11A homolog A, double strand break repair nuclease" K10865|1|0.0|1291|mmu:17535|double-strand break repair protein MRE11 GO:0000785//chromatin;GO:0043234//protein complex;GO:0000228//nuclear chromosome;GO:0044444//cytoplasmic part;GO:0000785//chromatin;GO:0043234//protein complex;GO:0000228//nuclear chromosome;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0003678//DNA helicase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity;GO:0003678//DNA helicase activity GO:0001934//positive regulation of protein phosphorylation;GO:0007127//meiosis I;GO:0043549//regulation of kinase activity;GO:0006996//organelle organization;GO:0007059//chromosome segregation;GO:0044767//single-organism developmental process;GO:0010948//negative regulation of cell cycle process;GO:0032392//DNA geometric change;GO:0006281//DNA repair;GO:0001934//positive regulation of protein phosphorylation;GO:0007127//meiosis I;GO:0043549//regulation of kinase activity;GO:0006996//organelle organization;GO:0007059//chromosome segregation;GO:0044767//single-organism developmental process;GO:0010948//negative regulation of cell cycle process;GO:0032392//DNA geometric change;GO:0006281//DNA repair "gi|148693060|gb|EDL25007.1|/0/meiotic recombination 11 homolog A (S. cerevisiae), isoform CRA_b, partial [Mus musculus]" 77940 3227 1.573333333 1.443333333 -0.124419835 Down 0.150541577 A930004D18Rik RIKEN cDNA A930004D18 gene - - - - gi|148676145|gb|EDL08092.1|/7.74171e-86/mCG147224 [Mus musculus] 19303 3751.42 27.22 26.53333333 -0.036861137 Down 0.150419346 Pxn paxillin K05760|1|0.0|1027|mmu:19303|paxillin GO:0043232;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0016020//membrane;GO:0016020//membrane;GO:0015630//microtubule cytoskeleton;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0044444//cytoplasmic part GO:0008092//cytoskeletal protein binding;GO:0019900//kinase binding;GO:0032947//protein complex scaffold;GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0051400//BH domain binding;GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0051400//BH domain binding;GO:0008092//cytoskeletal protein binding;GO:0019900//kinase binding;GO:0032947//protein complex scaffold GO:0006468//protein phosphorylation;GO:0006996//organelle organization;GO:0007044//cell-substrate junction assembly;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0060562//epithelial tube morphogenesis;GO:0031589//cell-substrate adhesion;GO:0030031//cell projection assembly;GO:0003012//muscle system process;GO:0038127//ERBB signaling pathway;GO:0000302//response to reactive oxygen species;GO:0007044//cell-substrate junction assembly;GO:0006996//organelle organization;GO:0006468//protein phosphorylation;GO:0030031//cell projection assembly;GO:0031589//cell-substrate adhesion;GO:0009966//regulation of signal transduction;GO:0060562//epithelial tube morphogenesis gi|21281693|ref|NP_035353.1|/0/paxillin isoform alpha [Mus musculus] 68273 2736 28.49 27.8 -0.035370739 Down 0.150419346 Pomgnt1 "protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase" "K09666|1|0.0|1207|mmu:68273|beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.-]" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity GO:0006486//protein glycosylation;GO:0006486//protein glycosylation;GO:0006486//protein glycosylation "gi|148698669|gb|EDL30616.1|/0/protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase, isoform CRA_b, partial [Mus musculus]" 70261 1171 0.85 0.75 -0.180572246 Down 0.150221896 Chp2 calcineurin-like EF hand protein 2 K17611|1|5e-102|373|mmu:70261|calcineurin B homologous protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0044459 GO:0005515//protein binding;GO:0046872//metal ion binding GO:0033173//calcineurin-NFAT signaling cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0030001//metal ion transport;GO:0006885//regulation of pH;GO:0051592//response to calcium ion;GO:0008283//cell proliferation;GO:0010921//regulation of phosphatase activity;GO:0006606//protein import into nucleus;GO:0006875//cellular metal ion homeostasis gi|672037923|ref|XP_008757967.1|/1.60591e-118/PREDICTED: calcineurin B homologous protein 2 isoform X2 [Rattus norvegicus] 77604 3457 0.843333333 0.746666667 -0.175638653 Down 0.150221896 Rbm12b2 RNA binding motif protein 12 B2 K14947|1|1e-16|91.7|lgi:LOTGIDRAFT_91728|epithelial splicing regulatory protein 1/2 - - - gi|71067349|ref|NP_945195.1|/0/RNA-binding protein 12B-B [Mus musculus] 234915 3647 0.803333333 0.706666667 -0.184968882 Down 0.150221896 Cep126 centrosomal protein 126 - - - - gi|113866019|ref|NP_001038989.1|/0/centrosomal protein of 126 kDa [Mus musculus] 102442 8655 0.816666667 0.72 -0.181750437 Down 0.150221896 Dennd4a DENN/MADD domain containing 4A K20163|1|0.0|3600|mmu:102442|DENN domain-containing protein 4 - - - gi|242332563|ref|NP_001156389.1|/0/C-myc promoter-binding protein [Mus musculus] 276950 4011 0.726666667 0.823333333 0.180182907 Up 0.150221896 Slfn8 schlafen 8 K04613|1|1e-08|65.9|rno:297590|vomeronasal 2 receptor GO:0044464;GO:0044464 - - gi|268370030|ref|NP_853523.2|/0/schlafen 8 isoform 1 [Mus musculus] 338354 5511 0.816666667 0.72 -0.181750437 Down 0.150221896 Zfp780b zinc finger protein 780B K09228|1|0.0|1735|mmu:338354|KRAB domain-containing zinc finger protein - - - gi|124486618|ref|NP_001074490.1|/0/zinc finger protein 780B [Mus musculus] 20643 508 24.74666667 25.42333333 0.038918989 Up 0.150212494 Snrpe small nuclear ribonucleoprotein E K11097|1|2e-41|170|umr:103657741|small nuclear ribonucleoprotein E GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding "GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter" "gi|148707696|gb|EDL39643.1|/1.59055e-44/small nuclear ribonucleoprotein E, isoform CRA_a, partial [Mus musculus]" 50932 4912.05 27.34333333 26.66 -0.036512347 Down 0.150212494 Mink1 misshapen-like kinase 1 (zebrafish) K04413|1|0.0|2145|mmu:50932|misshapen/NIK-related kinase [EC:2.7.11.1] GO:0097060//synaptic membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0097060//synaptic membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0097060//synaptic membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0097060//synaptic membrane;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity;GO:0032550;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity;GO:0032550;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity;GO:0032550;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity GO:0016358//dendrite development;GO:0007267//cell-cell signaling;GO:0007160//cell-matrix adhesion;GO:0016337//single organismal cell-cell adhesion;GO:0030036//actin cytoskeleton organization;GO:0007254//JNK cascade;GO:0006468//protein phosphorylation;GO:0010469//regulation of receptor activity;GO:0016477//cell migration;GO:0043383//negative T cell selection;GO:0016358//dendrite development;GO:0007267//cell-cell signaling;GO:0007160//cell-matrix adhesion;GO:0016337//single organismal cell-cell adhesion;GO:0030036//actin cytoskeleton organization;GO:0007254//JNK cascade;GO:0006468//protein phosphorylation;GO:0010469//regulation of receptor activity;GO:0016477//cell migration;GO:0043383//negative T cell selection;GO:0016358//dendrite development;GO:0007267//cell-cell signaling;GO:0007160//cell-matrix adhesion;GO:0016337//single organismal cell-cell adhesion;GO:0030036//actin cytoskeleton organization;GO:0007254//JNK cascade;GO:0006468//protein phosphorylation;GO:0010469//regulation of receptor activity;GO:0016477//cell migration;GO:0043383//negative T cell selection;GO:0016358//dendrite development;GO:0007267//cell-cell signaling;GO:0007160//cell-matrix adhesion;GO:0016337//single organismal cell-cell adhesion;GO:0030036//actin cytoskeleton organization;GO:0007254//JNK cascade;GO:0006468//protein phosphorylation;GO:0010469//regulation of receptor activity;GO:0016477//cell migration;GO:0043383//negative T cell selection gi|114052104|ref|NP_001039429.1|/0/misshapen-like kinase 1 isoform 4 [Mus musculus] 224129 5060 26.91333333 26.23666667 -0.036736647 Down 0.150212494 Adcy5 adenylate cyclase 5 K08045|1|0.0|2018|mmu:224129|adenylate cyclase 5 [EC:4.6.1.1] GO:0005929//cilium;GO:0031224//intrinsic component of membrane;GO:0005886//plasma membrane GO:0032550;GO:0046983//protein dimerization activity;GO:0004016//adenylate cyclase activity;GO:0043169//cation binding;GO:0019899//enzyme binding GO:0035588;GO:0015980//energy derivation by oxidation of organic compounds;GO:0007267//cell-cell signaling;GO:0038127//ERBB signaling pathway;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0033762//response to glucagon;GO:0032147//activation of protein kinase activity;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0010863//positive regulation of phospholipase C activity;GO:0046058//cAMP metabolic process;GO:0050905//neuromuscular process;GO:0044708//single-organism behavior;GO:0042044//fluid transport gi|148747309|ref|NP_001012783.3|/0/adenylate cyclase type 5 [Mus musculus] 77286 3279 1.1 0.99 -0.152003093 Down 0.150005641 Nkrf NF-kappaB repressing factor K13096|1|3e-06|57.4|api:100162504|splicing factor 4;K13094|2|5e-06|56.6|crg:105331958|RNA-binding protein 5/10;K19036|3|8e-06|55.8|aqu:100633563|ATP-dependent RNA/DNA helicase IGHMBP2 [EC:3.6.4.12 3.6.4.13] - - - "gi|148697037|gb|EDL28984.1|/0/NF-kappaB repressing factor, isoform CRA_b, partial [Mus musculus]" 237387 4311 1.11 1.003333333 -0.14575869 Down 0.150005641 Lrrc3 leucine rich repeat containing 3 K06839|1|2e-13|81.6|rno:360272|slit 2;K06850|5|2e-13|81.3|cmk:103177282|slit 3 GO:0031224//intrinsic component of membrane - - gi|537239643|gb|ERE86866.1|/8.91642e-141/leucine-rich repeat-containing protein 3 [Cricetulus griseus] 207181 7409 1.046666667 1.16 0.148322747 Up 0.150005641 Rbms3 "RNA binding motif, single stranded interacting protein" K13208|1|2e-21|108|shr:100934042|ELAV like protein 2/3/4;K13088|3|2e-19|102|ola:101172398|ELAV-like protein 1 GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - "gi|287324984|ref|NP_001165597.1|/0/RNA-binding motif, single-stranded-interacting protein 3 isoform 6 [Mus musculus] " 27418 3973 11.21 11.56666667 0.045186884 Up 0.149968032 Mkln1 "muskelin 1, intracellular mediator containing kelch motifs" - GO:0044424 - - gi|831228811|ref|XP_003791660.2|/0/PREDICTED: muskelin [Otolemur garnettii] 14451 3149 10.72333333 10.36 -0.049729432 Down 0.149968032 Gas1 growth arrest specific 1 K06232|1|1e-129|467|mmu:14451|growth arrest-specific 1 GO:0031225//anchored component of membrane GO:0005488//binding GO:0000278//mitotic cell cycle;GO:0006915//apoptotic process;GO:0030326//embryonic limb morphogenesis;GO:0008285//negative regulation of cell proliferation;GO:0008284//positive regulation of cell proliferation;GO:0001654//eye development;GO:0007224//smoothened signaling pathway;GO:0022402//cell cycle process;GO:0006935//chemotaxis;GO:0042471//ear morphogenesis;GO:0030154//cell differentiation;GO:0009953//dorsal/ventral pattern formation;GO:0016049//cell growth;GO:0048704//embryonic skeletal system morphogenesis gi|6679941|ref|NP_032112.1|/9.3856e-129/growth arrest-specific protein 1 [Mus musculus] 252870 5427 11.24666667 10.88666667 -0.046935183 Down 0.149968032 Usp7 ubiquitin specific peptidase 7 K11838|1|0.0|2205|mmu:252870|ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12] GO:0016604//nuclear body;GO:0044444//cytoplasmic part GO:0004175//endopeptidase activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0016790//thiolester hydrolase activity;GO:0042802//identical protein binding GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0006289//nucleotide-excision repair;GO:0012502//induction of programmed cell death;GO:0010608//posttranscriptional regulation of gene expression;GO:0019941//modification-dependent protein catabolic process;GO:0070646//protein modification by small protein removal;GO:0032502//developmental process gi|154146209|ref|NP_001003918.2|/0/ubiquitin carboxyl-terminal hydrolase 7 [Mus musculus] 320586 2131 9.963333333 9.603333333 -0.053093237 Down 0.149968032 A630089N07Rik RIKEN cDNA A630089N07 gene K09228|1|3e-44|182|rno:691280|KRAB domain-containing zinc finger protein - - - - 110006 2456 10.30666667 10.66333333 0.049080673 Up 0.149968032 Gusb "glucuronidase, beta" K01195|1|0.0|1317|mmu:110006|beta-glucuronidase [EC:3.2.1.31] GO:0000323//lytic vacuole "GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0005488//binding" GO:0044238//primary metabolic process gi|6754098|ref|NP_034498.1|/0/beta-glucuronidase precursor [Mus musculus] 223752 4139.35 10.36 10 -0.051024003 Down 0.149968032 Gramd4 GRAM domain containing 4 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0012501//programmed cell death;GO:0012501//programmed cell death gi|329663552|ref|NP_001192282.1|/0/GRAM domain-containing protein 4 isoform 2 [Mus musculus] 338349 5542 0.326666667 0.256666667 -0.347923303 Down 0.14992102 Cntln "centlein, centrosomal protein" K16467|1|3e-104|382|mmu:338349|centlein GO:0043232 - - gi|28893551|ref|NP_796359.1|/3.03159e-124/centlein isoform 2 [Mus musculus] 75541 1675.25 0.256666667 0.326666667 0.347923303 Up 0.14992102 Nat8f4 N-acetyltransferase 8 (GCN5-related) family member 4 K18309|1|4e-18|96.7|mze:101484234|aspartate N-acetyltransferase [EC:2.3.1.17];K20180|2|4e-18|96.7|mgp:100538837|vacuolar protein sorting-associated protein 16 - - - - 213783 7190 2.516666667 2.676666667 0.088923343 Up 0.149892813 Plekhg1 "pleckstrin homology domain containing, family G (with RhoGef domain) member 1" K16589|1|8e-71|157|mmu:230376|HAUS augmin-like complex subunit 6 - - - gi|755532665|ref|XP_011241378.1|/0/PREDICTED: pleckstrin homology domain-containing family G member 1 isoform X3 [Mus musculus] 213988 17289.51 3.09 3.273333333 0.083153686 Up 0.149892813 Tnrc6b trinucleotide repeat containing 6b K18412|1|0.0|2979|mmu:213988|trinucleotide repeat-containing gene 6 protein - - - gi|67782332|ref|NP_659061.2|/0/trinucleotide repeat-containing gene 6B protein isoform 1 [Mus musculus] 243867 2962 3.373333333 3.556666667 0.076350886 Up 0.149892813 Fbxo46 F-box protein 46 K10320|1|0.0|1085|mmu:243867|F-box protein 46 - GO:0005488//binding - "gi|148691163|gb|EDL23110.1|/0/mCG130067, partial [Mus musculus]" 73916 2540 2.626666667 2.786666667 0.085307313 Up 0.149892813 Ift57 intraflagellar transport 57 K04638|1|0.0|647|mmu:73916|intraflagellar transport protein 57 GO:0005815//microtubule organizing center;GO:0030425//dendrite;GO:0031513//nonmotile primary cilium GO:0005488//binding "GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated" gi|31560071|ref|NP_082956.2|/0/intraflagellar transport protein 57 homolog [Mus musculus] 216877 5179 2.57 2.41 -0.092735213 Down 0.149892813 Dhx33 DEAH (Asp-Glu-Ala-His) box polypeptide 33 K17820|1|0.0|1359|mmu:216877|ATP-dependent RNA helicase DHX33 [EC:3.6.4.13] GO:0031981//nuclear lumen "GO:0032550;GO:0042623//ATPase activity, coupled;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding" GO:0006360//transcription from RNA polymerase I promoter gi|30704933|gb|AAH52172.1|/0/DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Mus musculus] 99929 4154 3.573333333 3.39 -0.075985227 Down 0.149892813 Tiparp TCDD-inducible poly(ADP-ribose) polymerase K15259|1|0.0|1374|mmu:99929|poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30] - - - gi|31542102|ref|NP_849223.2|/0/TCDD-inducible poly [ADP-ribose] polymerase [Mus musculus] 56741 6227 2.693333333 2.53 -0.090255407 Down 0.149892813 Igdcc4 "immunoglobulin superfamily, DCC subclass, member 4" K06766|1|1e-71|275|api:100160084|neogenin - - - - 68904 5105.97 2.563333333 2.723333333 0.08735248 Up 0.149892813 Abhd13 abhydrolase domain containing 13 K06889|1|4e-180|635|cge:100754934|uncharacterized protein GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0003824//catalytic activity;GO:0003824//catalytic activity - gi|537265942|gb|ERE91012.1|/9.08078e-180/abhydrolase domain-containing protein 13 [Cricetulus griseus] 54367 2456.83 3.573333333 3.39 -0.075985227 Down 0.149892813 Zfp326 zinc finger protein 326 K13204|1|0.0|872|mmu:54367|zinc finger protein 326 GO:0043234//protein complex;GO:0034399//nuclear periphery;GO:0043234//protein complex;GO:0034399//nuclear periphery GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0006396//RNA processing;GO:0006354//DNA-templated transcription, elongation;GO:0006396//RNA processing;GO:0006354//DNA-templated transcription, elongation" "gi|148688243|gb|EDL20190.1|/3.73111e-142/zinc finger protein 326, isoform CRA_a, partial [Mus musculus]" 101994 4016 2.703333333 2.54 -0.089910917 Down 0.149892813 Champ1 chromosome alignment maintaining phosphoprotein 1 K00907|1|2e-21|107|myb:102259949|myosin-light-chain kinase [EC:2.7.11.18] GO:0015630//microtubule cytoskeleton;GO:0031981//nuclear lumen;GO:0000776//kinetochore GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0007080//mitotic metaphase plate congression;GO:0034502//protein localization to chromosome;GO:0072698 gi|32469497|ref|NP_862902.1|/0/chromosome alignment-maintaining phosphoprotein 1 [Mus musculus] 13557 4613.85 2.78 2.616666667 -0.08735473 Down 0.149892813 E2f3 E2F transcription factor 3 K06620|1|0.0|720|mmu:13557|transcription factor E2F3 GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0044212//transcription regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0051319;GO:0051318;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter gi|83523736|ref|NP_034223.1|/0/transcription factor E2F3 isoform E2f3a [Mus musculus] 69536 2194 6.243333333 5.986666667 -0.06056355 Down 0.149874008 Hemk1 HemK methyltransferase family member 1 K02493|1|0.0|665|mmu:69536|release factor glutamine methyltransferase [EC:2.1.1.297] GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity GO:0008213;GO:0006305 gi|255683365|ref|NP_598745.2|/0/hemK methyltransferase family member 1 [Mus musculus] 213484 3716 6.043333333 5.78 -0.064275027 Down 0.149874008 Nudt18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 K17817|1|4e-174|615|mmu:213484|8-oxo-dGDP phosphatase [EC:3.6.1.58] - GO:0046872//metal ion binding;GO:0017110//nucleoside-diphosphatase activity GO:0009154//purine ribonucleotide catabolic process;GO:0009155 "gi|148703939|gb|EDL35886.1|/0/nudix (nucleoside diphosphate linked moiety X)-type motif 18, isoform CRA_a, partial [Mus musculus]" 240283 12211 1.366666667 1.25 -0.128733314 Down 0.149695363 Dmxl1 Dmx-like 1 K12602|1|7e-08|64.7|lgi:LOTGIDRAFT_217484|WD repeat-containing protein 61;K16482|2|3e-07|62.4|tad:TRIADDRAFT_51125|centriolar protein POC1 - - - - 276891 2175 1.36 1.243333333 -0.129393522 Down 0.149695363 Timd4 T cell immunoglobulin and mucin domain containing 4 K20413|1|4e-28|129|tup:102473675|hepatitis A virus cellular receptor 1;K20414|4|5e-25|119|acs:100553921|hepatitis A virus cellular receptor 2 - - - gi|38532495|gb|AAR23483.1|/4.80359e-126/smuckler [Mus musculus] 17193 3584 0.583333333 0.673333333 0.207000371 Up 0.149582534 Mbd4 methyl-CpG binding domain protein 4 K10801|1|0.0|1060|mmu:17193|methyl-CpG-binding domain protein 4 [EC:3.2.2.-] GO:0043231//intracellular membrane-bounded organelle GO:0000700;GO:0003676//nucleic acid binding GO:0006281//DNA repair;GO:0009628//response to abiotic stimulus;GO:0006305;GO:0000077//DNA damage checkpoint gi|187960081|ref|NP_034904.2|/0/methyl-CpG-binding domain protein 4 [Mus musculus] 214901 3163 0.606666667 0.7 0.206450877 Up 0.149582534 Chtf18 "CTF18, chromosome transmission fidelity factor 18" K11269|1|0.0|1620|mmu:214901|chromosome transmission fidelity protein 18 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0016462//pyrophosphatase activity;GO:0032550 GO:0006259//DNA metabolic process;GO:0044763 gi|157951666|ref|NP_663384.2|/0/chromosome transmission fidelity protein 18 homolog [Mus musculus] 227671 1335 0.68 0.586666667 -0.212993723 Down 0.149582534 Gbgt1 "globoside alpha-1,3-N-acetylgalactosaminyltransferase 1" K00722|1|0.0|694|mmu:227671|globoside alpha-N-acetylgalactosaminyltransferase [EC:2.4.1.88] GO:0031224//intrinsic component of membrane GO:0008376//acetylgalactosaminyltransferase activity;GO:0043169//cation binding GO:0030258//lipid modification "gi|254587968|ref|NP_631936.2|/0/globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 [Mus musculus]" 72997 4214 0.576666667 0.666666667 0.209227962 Up 0.149582534 Kantr Kdm5c adjacent non-coding transcript - - - - - 26885 6566 0.676666667 0.583333333 -0.214124805 Down 0.149582534 Casp8ap2 caspase 8 associated protein 2 "K14572|1|7e-13|80.5|ssc:100525725|midasin;K15076|2|1e-07|62.8|pxy:105383863|transcription elongation factor B, polypeptide 3;K13100|3|2e-07|62.0|fab:101819752|pre-mRNA-splicing factor CWC22" - - - - 16396 5187 4.576666667 4.37 -0.06666394 Down 0.149413291 Itch "itchy, E3 ubiquitin protein ligase" K05632|1|0.0|1652|mmu:16396|atrophin-1 interacting protein 4 [EC:2.3.2.26] GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0044444//cytoplasmic part GO:0042379//chemokine receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0042379//chemokine receptor binding;GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination;GO:0002666//positive regulation of T cell tolerance induction;GO:0042130//negative regulation of T cell proliferation;GO:0006915//apoptotic process;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0007254//JNK cascade;GO:0002698;GO:0019941//modification-dependent protein catabolic process;GO:0009896;GO:0006952//defense response;GO:0031399//regulation of protein modification process;GO:0000209//protein polyubiquitination;GO:0002666//positive regulation of T cell tolerance induction;GO:0042130//negative regulation of T cell proliferation;GO:0006915//apoptotic process;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0007254//JNK cascade;GO:0002698;GO:0019941//modification-dependent protein catabolic process;GO:0009896;GO:0006952//defense response;GO:0031399//regulation of protein modification process gi|60360210|dbj|BAD90349.1|/0/mKIAA4011 protein [Mus musculus] 16431 1632 4.723333333 4.51 -0.066677919 Down 0.149413291 Itm2a integral membrane protein 2A K18241|1|2e-143|511|mmu:16431|integral membrane protein 2A GO:0031224//intrinsic component of membrane - - gi|344245637|gb|EGW01741.1|/3.32642e-150/Integral membrane protein 2A [Cricetulus griseus] 66056 1105 10.29333333 10.64666667 0.04869156 Up 0.149309865 Zfp524 zinc finger protein 524 K09228|1|4e-26|121|lcm:106705198|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|13384694|ref|NP_079600.1|/1.95846e-171/zinc finger protein 524 [Mus musculus] 13209 6008 11.34666667 10.99666667 -0.045202259 Down 0.149309865 Ddx6 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 K12614|1|0.0|929|mmu:13209|ATP-dependent RNA helicase DDX6/DHH1 [EC:3.6.4.13] - - - - 67884 1696 9.166666667 9.52 0.054564361 Up 0.149309865 1810043G02Rik RIKEN cDNA 1810043G02 gene K16532|1|1e-09|67.4|lcm:102365696|centrosomal protein CEP72;K19753|2|4e-08|62.4|lgi:LOTGIDRAFT_222768|protein TilB;K16770|5|2e-07|60.1|crg:105328698|centriolin GO:0016020//membrane;GO:0044424 - GO:0048858//cell projection morphogenesis;GO:0022604//regulation of cell morphogenesis;GO:0006996//organelle organization "gi|149043618|gb|EDL97069.1|/8.13898e-124/similar to RIKEN cDNA 1810043G02; DNA segment, Chr 10, Johns Hopkins University 13, expressed, isoform CRA_a [Rattus norvegicus]" 108100 2348.94 10.91333333 11.26666667 0.045968925 Up 0.149309865 Baiap2 brain-specific angiogenesis inhibitor 1-associated protein 2 K05627|1|0.0|877|mmu:108100|BAI1-associated protein 2 GO:0005856//cytoskeleton;GO:0031981//nuclear lumen;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0031981//nuclear lumen;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043232;GO:0042995//cell projection;GO:0044444//cytoplasmic part "GO:0030674//protein binding, bridging;GO:0019904//protein domain specific binding;GO:0030674//protein binding, bridging;GO:0019904//protein domain specific binding;GO:0030674//protein binding, bridging;GO:0019904//protein domain specific binding" GO:0007265//Ras protein signal transduction;GO:0051707//response to other organism;GO:0007015//actin filament organization;GO:0022604//regulation of cell morphogenesis;GO:0050804//modulation of synaptic transmission;GO:0031175//neuron projection development;GO:0030031//cell projection assembly;GO:0007265//Ras protein signal transduction;GO:0051707//response to other organism;GO:0007015//actin filament organization;GO:0022604//regulation of cell morphogenesis;GO:0050804//modulation of synaptic transmission;GO:0031175//neuron projection development;GO:0030031//cell projection assembly;GO:0007265//Ras protein signal transduction;GO:0051707//response to other organism;GO:0007015//actin filament organization;GO:0050804//modulation of synaptic transmission;GO:0031175//neuron projection development;GO:0030031//cell projection assembly gi|262231776|ref|NP_001032844.2|/0/brain-specific angiogenesis inhibitor 1-associated protein 2 isoform a [Mus musculus] 107526 1739.39 21.89333333 21.26666667 -0.041897703 Down 0.149262853 Gimap4 "GTPase, IMAP family member 4" - GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen GO:0032550;GO:0032550;GO:0032550;GO:0032550;GO:0032550 - gi|755515754|ref|XP_011239412.1|/2.68114e-54/PREDICTED: GTPase IMAP family member 4 isoform X2 [Mus musculus] 74597 1530 0.45 0.533333333 0.245112498 Up 0.149197036 4833418N02Rik RIKEN cDNA 4833418N02 gene - - - - "gi|148706682|gb|EDL38629.1|/1.40382e-54/mCG145010, partial [Mus musculus]" 56489 3203 0.426666667 0.506666667 0.247927513 Up 0.149197036 Ikbke inhibitor of kappaB kinase epsilon K07211|1|0.0|1439|mmu:56489|inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10] GO:0016604//nuclear body GO:0032550;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0006974//cellular response to DNA damage stimulus "gi|148707764|gb|EDL39711.1|/0/inhibitor of kappaB kinase epsilon, isoform CRA_b, partial [Mus musculus]" 29807 2531 0.526666667 0.443333333 -0.248498313 Down 0.149197036 Tpk1 thiamine pyrophosphokinase K00949|1|9e-141|503|mmu:29807|thiamine pyrophosphokinase [EC:2.7.6.2] - - - gi|902763345|ref|NP_001298040.1|/1.05739e-111/thiamin pyrophosphokinase 1 isoform 2 [Mus musculus] 229776 4338 0.483333333 0.406666667 -0.249171752 Down 0.149197036 Cdc14a CDC14 cell division cycle 14A K06639|1|0.0|966|mmu:229776|cell division cycle 14 [EC:3.1.3.16 3.1.3.48] GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen;GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity GO:0044763;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0044763;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|291167780|ref|NP_001167024.1|/0/dual specificity protein phosphatase CDC14A isoform 2 [Mus musculus] 16541 1479 0.4 0.476666667 0.252980741 Up 0.149197036 Napsa napsin A aspartic peptidase K08565|1|0.0|836|mmu:16541|napsin-A [EC:3.4.23.-] GO:0044421;GO:0000323//lytic vacuole;GO:0042599//lamellar body GO:0004175//endopeptidase activity;GO:0005488//binding GO:0048875//chemical homeostasis within a tissue;GO:0006508//proteolysis gi|6680552|ref|NP_032463.1|/0/napsin-A precursor [Mus musculus] 16764 7251 0.52 0.436666667 -0.251979217 Down 0.149197036 Aff3 "AF4/FMR2 family, member 3" K15195|1|0.0|1981|mmu:16764|AF4/FMR2 family member 3 GO:0031981//nuclear lumen GO:0043566//structure-specific DNA binding GO:0034097//response to cytokine;GO:0030326//embryonic limb morphogenesis gi|568905865|ref|XP_006495800.1|/0/PREDICTED: AF4/FMR2 family member 3 isoform X5 [Mus musculus] 67296 2154 0.413333333 0.49 0.245476034 Up 0.149197036 Socs4 suppressor of cytokine signaling 4 K04697|1|0.0|836|mmu:67296|suppressor of cytokine signaling 4 - - GO:0032446//protein modification by small protein conjugation;GO:0040007//growth;GO:0007176//regulation of epidermal growth factor-activated receptor activity gi|49355822|ref|NP_543119.2|/0/suppressor of cytokine signaling 4 [Mus musculus] 100502745 468 0.45 0.533333333 0.245112498 Up 0.149197036 2900009J06Rik RIKEN cDNA 2900009J06 gene K03392|1|1e-15|84.0|ptg:102952800|aminocarboxymuconate-semialdehyde decarboxylase [EC:4.1.1.45] - - - - 18717 4281.13 20.98 21.60333333 0.042239255 Up 0.149084208 Pip5k1c "phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma" K00889|1|0.0|1015|rno:314641|1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68] GO:0030054//cell junction;GO:0042995//cell projection;GO:0016020//membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0016020//membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0016020//membrane;GO:0030054//cell junction;GO:0042995//cell projection;GO:0016020//membrane GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0016307//phosphatidylinositol phosphate kinase activity GO:0046488//phosphatidylinositol metabolic process;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006897//endocytosis;GO:0046488//phosphatidylinositol metabolic process;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006897//endocytosis;GO:0046488//phosphatidylinositol metabolic process;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006897//endocytosis;GO:0046488//phosphatidylinositol metabolic process;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006897//endocytosis gi|652698048|ref|NP_001280575.1|/0/phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform 3 [Mus musculus] 381820 2365.13 24.22 24.83666667 0.036272697 Up 0.149084208 Smim10l1 small integral membrane protein 10 like 1 - - - - "gi|148697822|gb|EDL29769.1|/2.96503e-46/mCG1039243, isoform CRA_b, partial [Mus musculus]" 51875 931.28 22.74333333 22.12666667 -0.039657587 Down 0.149084208 Tmem141 transmembrane protein 141 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|158517816|ref|NP_001035219.2|/3.33726e-46/transmembrane protein 141 isoform 1 [Mus musculus] 11769 1277 21.95666667 22.58 0.040386437 Up 0.149084208 Ap1s1 "adaptor protein complex AP-1, sigma 1" K12394|1|3e-94|347|ecb:100060194|AP-1 complex subunit sigma 1/2 GO:0005764//lysosome;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0005802//trans-Golgi network GO:0022892//substrate-specific transporter activity GO:0002478;GO:0044764;GO:0006897//endocytosis;GO:0048193//Golgi vesicle transport;GO:0050688//regulation of defense response to virus;GO:0015031//protein transport gi|953870558|ref|XP_005598720.2|/2.65069e-93/PREDICTED: AP-1 complex subunit sigma-1A [Equus caballus] 215900 1095 0.01 0.046666667 2.222392421 Up 0.149074805 Fam26f "family with sequence similarity 26, member F" K19739|1|3e-25|118|mdo:100028621|calcium homeostasis modulator protein 2 GO:0031224//intrinsic component of membrane - - gi|31982193|ref|NP_780658.2|/7.35996e-163/protein FAM26F [Mus musculus] 208890 2371 0.046666667 0.01 -2.222392421 Down 0.149074805 Slc26a7 "solute carrier family 26, member 7" "K13962|1|0.0|1229|mmu:208890|solute carrier family 26 (anion exchange transporter), member 7" GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0005253//anion channel activity;GO:0015103//inorganic anion transmembrane transporter activity GO:0015698//inorganic anion transport;GO:0006835//dicarboxylic acid transport gi|227496621|ref|NP_666059.2|/0/anion exchange transporter [Mus musculus] 100503816 1241 0.01 0.046666667 2.222392421 Up 0.149074805 Gm16548 predicted gene 16548 K03902|1|2e-16|89.4|mmu:14067|coagulation factor V (labile factor) GO:0044421;GO:0030141//secretory granule GO:0046914//transition metal ion binding GO:0007599//hemostasis;GO:0003013//circulatory system process;GO:0022610 "gi|148707315|gb|EDL39262.1|/1.32978e-41/mCG146334, partial [Mus musculus]" 280621 1225 0.046666667 0.01 -2.222392421 Down 0.149074805 BC089491 cDNA sequence BC089491 - - - - - 93968 1150 0.046666667 0.01 -2.222392421 Down 0.149074805 Klra21 "killer cell lectin-like receptor subfamily A, member 21" K10074|1|2e-16|89.4|ocu:100339146|C-type lectin domain family 7 member A;K10069|2|3e-15|85.1|myb:106725970|C-type lectin domain family 1 member A;K17517|3|1e-14|83.2|ptg:102951146|C-type lectin domain family 12 member B - - - - 16917 1219 0.046666667 0.01 -2.222392421 Down 0.149074805 Lmx1b LIM homeobox transcription factor 1 beta K09371|1|2e-168|593|mmu:16917|LIM homeobox transcription factor 1 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0043010//camera-type eye development;GO:0030198//extracellular matrix organization;GO:0035108//limb morphogenesis;GO:0043009//chordate embryonic development;GO:0003002//regionalization;GO:0021953//central nervous system neuron differentiation;GO:0007420//brain development;GO:0016477//cell migration gi|255759880|ref|NP_034855.2|/1.99246e-167/LIM homeobox transcription factor 1-beta [Mus musculus] 100038394 1170 0.01 0.046666667 2.222392421 Up 0.149074805 Gm10512 predicted gene 10512 - - - - gi|74189276|dbj|BAE22677.1|/1.13886e-23/unnamed protein product [Mus musculus] 69441 1199 0.046666667 0.01 -2.222392421 Down 0.149074805 1700023F06Rik RIKEN cDNA 1700023F06 gene K18626|1|2e-09|66.2|cmk:103191497|trichohyalin;K10840|3|1e-06|56.6|xla:735211|centrin-2;K16465|4|4e-06|55.1|cfa:490531|centrin-1 - - - gi|360039201|ref|NP_001241653.1|/0/uncharacterized protein LOC69441 [Mus musculus] 210554 1186 0.01 0.046666667 2.222392421 Up 0.149074805 Hus1b HUS1 checkpoint clamp component B K10996|1|3e-158|560|mmu:210554|checkpoint protein HUS1B - - - - 15229 2461 0.01 0.046666667 2.222392421 Up 0.149074805 Foxd1 forkhead box D1 K09397|1|3e-70|269|mmu:15229|forkhead box protein D GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0001656//metanephros development;GO:0048518;GO:0006355//regulation of transcription, DNA-templated;GO:0048468//cell development;GO:0072130;GO:0007399//nervous system development" gi|157057168|ref|NP_032268.2|/2.15637e-69/forkhead box protein D1 [Mus musculus] 328314 1297 0.046666667 0.01 -2.222392421 Down 0.149074805 Gm5086 predicted gene 5086 - - - - - 93970 1239 0.046666667 0.01 -2.222392421 Down 0.149074805 Klra18 "killer cell lectin-like receptor, subfamily A, member 18" K10074|1|3e-16|88.6|cmy:102930455|C-type lectin domain family 7 member A;K17515|2|6e-15|84.3|cmy:102931116|C-type lectin domain family 9 member A;K17517|3|8e-15|84.0|myb:102251819|C-type lectin domain family 12 member B;K10069|5|4e-14|81.6|cjc:100401523|C-type lectin domain family 1 member A GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0022610;GO:0007154//cell communication "gi|21361220|ref|NP_444383.1|/1.98602e-154/killer cell lectin-like receptor, subfamily A, member 18 [Mus musculus]" 102633081 2069 0.01 0.046666667 2.222392421 Up 0.149074805 Gm12610 predicted gene 12610 - - - - - 233752 2339 0.046666667 0.01 -2.222392421 Down 0.149074805 Insc inscuteable homolog (Drosophila) - GO:0044424 - GO:0048731//system development;GO:0040001//establishment of mitotic spindle localization;GO:0030855//epithelial cell differentiation gi|116248173|sp|Q3HNM7.2|INSC_MOUSE/0/RecName: Full=Protein inscuteable homolog; AltName: Full=Minsc 21674 1188 0.046666667 0.01 -2.222392421 Down 0.149074805 Sry sex determining region of Chr Y K09266|1|2e-81|305|mmu:21674|sex-determining region Y protein (SOX group A) GO:0043231//intracellular membrane-bounded organelle "GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding" GO:0048869//cellular developmental process;GO:0051094//positive regulation of developmental process;GO:0008406//gonad development;GO:0006366//transcription from RNA polymerase II promoter gi|84105543|gb|AAI11529.1|/1.77811e-80/Sry protein [Mus musculus] 12737 3263 0.01 0.046666667 2.222392421 Up 0.149074805 Cldn1 claudin 1 K06087|1|1e-91|340|mmu:12737|claudin GO:0043296//apical junction complex;GO:0044459;GO:0031224//intrinsic component of membrane GO:0005515//protein binding GO:0016337//single organismal cell-cell adhesion;GO:0034330 gi|7710002|ref|NP_057883.1|/1.05749e-90/claudin-1 [Mus musculus] 23958 1999 0.01 0.046666667 2.222392421 Up 0.149074805 Nr2e3 "nuclear receptor subfamily 2, group E, member 3" K08546|1|0.0|776|mmu:23958|nuclear receptor subfamily 2 group E member 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0043010//camera-type eye development;GO:0009755//hormone-mediated signaling pathway;GO:0008283//cell proliferation;GO:0007468//regulation of rhodopsin gene expression;GO:0001754//eye photoreceptor cell differentiation gi|7305323|ref|NP_038736.1|/0/photoreceptor-specific nuclear receptor [Mus musculus] 83885 1346 0.046666667 0.01 -2.222392421 Down 0.149074805 Slc25a2 "solute carrier family 25 (mitochondrial carrier, ornithine transporter) member 2" K15101|1|3e-139|497|mmu:83885|solute carrier family 25 (mitochondrial ornithine transporter) member 2/15 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0008324//cation transmembrane transporter activity GO:0006839//mitochondrial transport;GO:0019627//urea metabolic process gi|226494439|ref|NP_001152747.1|/2.92733e-138/mitochondrial ornithine transporter 2 [Mus musculus] 11839 1215 0.046666667 0.01 -2.222392421 Down 0.149074805 Areg amphiregulin K09782|1|6e-90|333|mmu:11839|amphiregulin - - - - 668178 1446 0.046666667 0.01 -2.222392421 Down 0.149074805 Mettl7a3 methyltransferase like 7A3 K07755|1|2e-06|56.6|cin:100181209|arsenite methyltransferase [EC:2.1.1.137] GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle GO:0016741 GO:0008152//metabolic process gi|125490373|ref|NP_001074940.1|/2.82109e-142/UbiE3 protein [Mus musculus] 217214 2122 0.01 0.046666667 2.222392421 Up 0.149074805 Nags N-acetylglutamate synthase K11067|1|0.0|904|mmu:217214|N-acetylglutamate synthase [EC:2.3.1.1] GO:0043231//intracellular membrane-bounded organelle GO:0008080//N-acetyltransferase activity GO:0009064//glutamine family amino acid metabolic process "gi|22003874|ref|NP_665828.1|/0/N-acetylglutamate synthase, mitochondrial precursor [Mus musculus]" 14181 1198 0.01 0.046666667 2.222392421 Up 0.149074805 Fgfbp1 fibroblast growth factor binding protein 1 - GO:0044421;GO:0044464;GO:0016020//membrane;GO:0044421;GO:0044464;GO:0016020//membrane GO:0019838//growth factor binding;GO:0019838//growth factor binding GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0008283//cell proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0008283//cell proliferation gi|47132512|ref|NP_032035.2|/4.80209e-134/fibroblast growth factor-binding protein 1 precursor [Mus musculus] 328789 1275 0.01 0.046666667 2.222392421 Up 0.149074805 Lhfpl5 lipoma HMGIC fusion partner-like 5 - - - - - 71432 1166 0.01 0.046666667 2.222392421 Up 0.149074805 5430437J10Rik RIKEN cDNA 5430437J10 gene K02726|1|1e-11|49.7|mdo:100013483|20S proteasome subunit alpha 2 [EC:3.4.25.1] - - - - 27424 1234 0.046666667 0.01 -2.222392421 Down 0.149074805 Klra16 "killer cell lectin-like receptor, subfamily A, member 16" K10074|1|3e-17|92.0|cmy:102930455|C-type lectin domain family 7 member A;K17515|2|1e-16|90.1|cmy:102931116|C-type lectin domain family 9 member A;K17517|4|1e-14|83.6|ocu:100342539|C-type lectin domain family 12 member B;K10069|5|1e-14|83.2|cjc:100401523|C-type lectin domain family 1 member A GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0022610;GO:0007154//cell communication "gi|9256549|ref|NP_038822.3|/2.17947e-153/killer cell lectin-like receptor, subfamily A, member 16 [Mus musculus]" 623198 1191 0.01 0.046666667 2.222392421 Up 0.149074805 Gm6408 predicted gene 6408 K08732|1|1e-17|93.2|ptg:102965767|ral guanine nucleotide dissociation stimulator - - - - 108069 3536 0.046666667 0.01 -2.222392421 Down 0.149074805 Grm3 "glutamate receptor, metabotropic 3" K04605|1|0.0|1684|mmu:108069|metabotropic glutamate receptor 2/3 GO:0031224//intrinsic component of membrane;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0097386//glial cell projection GO:0016247//channel regulator activity;GO:0001640//adenylate cyclase inhibiting G-protein coupled glutamate receptor activity GO:0019233//sensory perception of pain;GO:0007270//neuron-neuron synaptic transmission;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway gi|32469489|ref|NP_862898.1|/0/metabotropic glutamate receptor 3 precursor [Mus musculus] 68393 1218 0.046666667 0.01 -2.222392421 Down 0.149074805 Mogat1 monoacylglycerol O-acyltransferase 1 K14458|1|0.0|711|mmu:68393|2-acylglycerol O-acyltransferase 1 [EC:2.3.1.22] - - - - 407789 2260 0.046666667 0.01 -2.222392421 Down 0.149074805 BC048644 cDNA sequence BC048644 K01672|1|2e-25|120|mmu:12352|carbonic anhydrase [EC:4.2.1.1] - - - - 26898 1282 0.046666667 0.01 -2.222392421 Down 0.149074805 Ctsj cathepsin J K09599|1|0.0|708|mmu:26898|cathepsin P [EC:3.4.22.-];K01365|3|2e-133|478|cge:100772318|cathepsin L [EC:3.4.22.15];K09601|4|6e-122|439|rno:498688|cathepsin R [EC:3.4.22.-] GO:0044444//cytoplasmic part "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process gi|7770062|ref|NP_036137.1|/0/cathepsin J precursor [Mus musculus] 654821 2220 0.01 0.046666667 2.222392421 Up 0.149074805 Gcnt7 glucosaminyl (N-acetyl) transferase family member 7 "K00742|1|1e-89|333|pbi:103065974|N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase [EC:2.4.1.150]" - - - - 67639 1176 0.046666667 0.01 -2.222392421 Down 0.149074805 4930474N09Rik RIKEN cDNA 4930474N09 gene - - - - gi|148686972|gb|EDL18919.1|/3.81332e-27/mCG1048049 [Mus musculus] 272667 2318 0.046666667 0.01 -2.222392421 Down 0.149074805 Smok4a sperm motility kinase 4A K08798|1|2e-139|499|cge:100775051|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] - - - - 330820 1023 0.01 0.046666667 2.222392421 Up 0.149074805 4933402J07Rik RIKEN cDNA 4933402J07 gene - - - - gi|29244532|ref|NP_808569.1|/1.47997e-130/uncharacterized protein C16orf78 homolog [Mus musculus] 13874 4136 0.046666667 0.01 -2.222392421 Down 0.149074805 Ereg epiregulin K09784|1|2e-81|307|mmu:13874|epiregulin - - - - 234724 2377 0.01 0.046666667 2.222392421 Up 0.149074805 Tat tyrosine aminotransferase K00815|1|0.0|925|mmu:234724|tyrosine aminotransferase [EC:2.6.1.5] GO:0043231//intracellular membrane-bounded organelle GO:0070546;GO:0070547;GO:0031406//carboxylic acid binding GO:0006558//L-phenylalanine metabolic process;GO:0010038//response to metal ion;GO:0043648//dicarboxylic acid metabolic process;GO:0006570//tyrosine metabolic process;GO:0009064//glutamine family amino acid metabolic process;GO:0031960//response to corticosteroid;GO:0009063//cellular amino acid catabolic process;GO:0006006//glucose metabolic process;GO:0006950//response to stress gi|22122769|ref|NP_666326.1|/0/tyrosine aminotransferase [Mus musculus] 382384 1248 0.046666667 0.01 -2.222392421 Down 0.149074805 Odf3l2 outer dense fiber of sperm tails 3-like 2 K14007|1|4e-06|55.1|xma:102223221|protein transport protein SEC24 GO:0005874//microtubule - - gi|85701995|ref|NP_001028645.1|/3.07131e-163/outer dense fiber protein 3-like protein 2 [Mus musculus] 229697 1234 0.01 0.046666667 2.222392421 Up 0.149074805 Cym chymosin K01378|1|0.0|775|mmu:229697|chymosin [EC:3.4.23.4] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|162287225|ref|NP_001104613.1|/0/embryonic pepsinogen precursor [Mus musculus] 381411 2225 0.046666667 0.01 -2.222392421 Down 0.149074805 Accsl 1-aminocyclopropane-1-carboxylate synthase (non-functional)-like K00815|1|2e-10|70.5|hmg:100204677|tyrosine aminotransferase [EC:2.6.1.5] - "GO:0043168//anion binding;GO:0016769//transferase activity, transferring nitrogenous groups" GO:0008152//metabolic process gi|110625627|ref|NP_001028624.2|/0/probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2 [Mus musculus] 319893 2004 0.01 0.046666667 2.222392421 Up 0.149074805 A230057D06Rik RIKEN cDNA A230057D06 gene - - - - - 56640 1237 0.046666667 0.01 -2.222392421 Down 0.149074805 Klk4 "kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)" K08666|1|6e-151|536|mmu:56640|kallikrein 4 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0042475//odontogenesis of dentin-containing tooth gi|9910516|ref|NP_064312.1|/5.04333e-150/kallikrein-4 precursor [Mus musculus] 242620 2947 0.01 0.046666667 2.222392421 Up 0.149074805 Dmrta2 doublesex and mab-3 related transcription factor like family A2 K19491|1|2e-172|609|mmu:242620|doublesex- and mab-3-related transcription factor 4/5 - GO:0005488//binding GO:0007519//skeletal muscle tissue development gi|25989643|gb|AAN10254.1|/1.41877e-171/doublesex- and mab-3-related transcription factor 5 [Mus musculus] 74264 1210 0.046666667 0.01 -2.222392421 Down 0.149074805 Rnf138rt1 "ring finger protein 138, retrogene 1" K10668|1|7e-133|476|mmu:74264|E3 ubiquitin-protein ligase RNF138 [EC:2.3.2.27] GO:0044464 GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0019900//kinase binding GO:0007166//cell surface receptor signaling pathway;GO:0032446//protein modification by small protein conjugation gi|13386356|ref|NP_083118.1|/5.98571e-132/E3 ubiquitin-protein ligase RNF138-like [Mus musculus] 436062 1190 0.01 0.046666667 2.222392421 Up 0.149074805 Fam92b "family with sequence similarity 92, member B" K15421|1|2e-34|149|nvi:100123748|secretion-regulating guanine nucleotide exchange factor;K10837|2|2e-27|125|hmg:100200454|O-phosphoseryl-tRNA(Sec) kinase [EC:2.7.1.164];K02258|3|2e-13|79.0|smm:Smp_141470|cytochrome c oxidase assembly protein subunit 11 - - - gi|283806727|ref|NP_001029152.2|/5.98504e-153/protein FAM92B [Mus musculus] 68709 4022 0.01 0.046666667 2.222392421 Up 0.149074805 Cilp2 cartilage intermediate layer protein 2 K05141|1|3e-12|77.4|gja:107124770|tumor necrosis factor receptor superfamily member 1B;K19031|4|2e-11|75.1|dre:100003660|cell migration-inducing and hyaluronan-binding protein [EC:3.2.1.35] - GO:0016791//phosphatase activity;GO:0016462//pyrophosphatase activity - gi|168480100|ref|NP_081094.2|/0/cartilage intermediate layer protein 2 precursor [Mus musculus] 71416 1253 0.01 0.046666667 2.222392421 Up 0.149074805 5430425K12Rik RIKEN cDNA 5430425K12 gene - - - - - 56460 2857 0.01 0.046666667 2.222392421 Up 0.149074805 Pkp3 plakophilin 3 K12642|1|5e-73|278|xla:443776|plakophilin 2 GO:0005913//cell-cell adherens junction;GO:0043231//intracellular membrane-bounded organelle;GO:0005913//cell-cell adherens junction;GO:0043231//intracellular membrane-bounded organelle - GO:0022610;GO:0022610 gi|242332587|ref|NP_001156396.1|/0/plakophilin-3 isoform 2 [Mus musculus] 246788 2440 0.01 0.046666667 2.222392421 Up 0.149074805 Trpv3 "transient receptor potential cation channel, subfamily V, member 3" K04972|1|0.0|1371|mmu:246788|transient receptor potential cation channel subfamily V member 3 - - - gi|266458389|ref|NP_659567.2|/0/transient receptor potential cation channel subfamily V member 3 [Mus musculus] 408028 1484 0.133333333 0.196666667 0.560714954 Up 0.149037196 Arhgap20os "Rho GTPase activating protein 20, opposite strand" K10405|1|3e-14|50.4|rno:294286|kinesin family member C1 GO:0044464 GO:0008047//enzyme activator activity;GO:0017016//Ras GTPase binding;GO:0008289//lipid binding GO:0007266//Rho protein signal transduction "gi|148693834|gb|EDL25781.1|/8.47213e-49/mCG146249, partial [Mus musculus]" 21892 4928 0.13 0.19 0.547487795 Up 0.149037196 Tll1 tolloid-like K09608|1|0.0|2149|mmu:21892|tolloid-like protein 1 [EC:3.4.24.-] - GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0043062//extracellular structure organization;GO:0048731//system development;GO:0019538//protein metabolic process;GO:0048869//cellular developmental process gi|117414180|ref|NP_033416.2|/0/tolloid-like protein 1 precursor [Mus musculus] 66720 2012 0.123333333 0.183333333 0.571906348 Up 0.149037196 Klhl10 kelch-like 10 K10448|1|0.0|1301|ocu:100346488|kelch-like protein 10 GO:0044424 GO:0005488//binding GO:0030539//male genitalia development;GO:0007281//germ cell development;GO:0001894//tissue homeostasis;GO:0032989;GO:0008406//gonad development gi|395826410|ref|XP_003786411.1|/0/PREDICTED: kelch-like protein 10 isoform X1 [Otolemur garnettii] 78758 3390 0.13 0.19 0.547487795 Up 0.149037196 4921518K17Rik RIKEN cDNA 4921518K17 gene - - - - - 245607 3761 0.196666667 0.133333333 -0.560714954 Down 0.149037196 Gprasp2 G protein-coupled receptor associated sorting protein 2 "K17498|1|1e-10|72.4|hst:105184735|transcription factor SPN1;K20056|3|1e-07|62.0|oas:101117930|PDZ domain-containing protein GIPC;K12893|5|4e-07|60.5|ocu:100350179|splicing factor, arginine/serine-rich 4/5/6" GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005102//receptor binding;GO:0005102//receptor binding;GO:0005102//receptor binding - gi|244793066|ref|NP_001156487.1|/0/G-protein coupled receptor-associated sorting protein 2 [Mus musculus] 20537 3933 0.276666667 0.346666667 0.325400287 Up 0.148999586 Slc5a1 "solute carrier family 5 (sodium/glucose cotransporter), member 1" "K14158|1|0.0|1134|mmu:20537|solute carrier family 5 (sodium/glucose cotransporter), member 1" GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0005903//brush border;GO:0044459 GO:0005355//glucose transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0006814//sodium ion transport;GO:0044763;GO:0015758//glucose transport;GO:0022600//digestive system process gi|26329187|dbj|BAC28332.1|/0/unnamed protein product [Mus musculus] 100504689 1117 0.27 0.34 0.332575339 Up 0.148999586 Plscr5 "phospholipid scramblase family, member 5" - - - - gi|307574650|ref|NP_001182622.1|/2.2859e-159/phospholipid scramblase family member 5 [Mus musculus] 218121 2881 0.323333333 0.256666667 -0.333126301 Down 0.148999586 Mboat1 membrane bound O-acyltransferase domain containing 1 K13517|1|0.0|926|mmu:218121|lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0016740//transferase activity GO:0006644//phospholipid metabolic process gi|23956314|ref|NP_705774.1|/0/lysophospholipid acyltransferase 1 [Mus musculus] 16416 5795 0.93 0.826666667 -0.169925001 Down 0.148971379 Itgb3 integrin beta 3 K06493|1|0.0|1531|mmu:16416|integrin beta 3 GO:0009986//cell surface;GO:0048770;GO:0008305//integrin complex;GO:0005924//cell-substrate adherens junction "GO:0005172//vascular endothelial growth factor receptor binding;GO:0033218//amide binding;GO:0032403//protein complex binding;GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups" GO:0000902//cell morphogenesis;GO:0033627//cell adhesion mediated by integrin;GO:0010883//regulation of lipid storage;GO:0006869//lipid transport;GO:0008284//positive regulation of cell proliferation;GO:0032846;GO:0009612//response to mechanical stimulus;GO:0010761//fibroblast migration;GO:0010742//macrophage derived foam cell differentiation;GO:0030168//platelet activation;GO:0043410//positive regulation of MAPK cascade;GO:0002684//positive regulation of immune system process;GO:0072110//glomerular mesangial cell proliferation;GO:0010871//negative regulation of receptor biosynthetic process;GO:0010594//regulation of endothelial cell migration;GO:0031589//cell-substrate adhesion;GO:0008219//cell death;GO:0034329//cell junction assembly;GO:0001525//angiogenesis;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0014909//smooth muscle cell migration;GO:0042493//response to drug;GO:0006875//cellular metal ion homeostasis;GO:0045860//positive regulation of protein kinase activity;GO:1900729 gi|160358856|ref|NP_058060.2|/0/integrin beta-3 precursor [Mus musculus] 237911 6933 0.753333333 0.85 0.174174474 Up 0.148971379 Brip1 BRCA1 interacting protein C-terminal helicase 1 K15362|1|0.0|2360|mmu:237911|fanconi anemia group J protein [EC:3.6.4.12] GO:0005635//nuclear envelope "GO:0003678//DNA helicase activity;GO:0043169//cation binding;GO:0032550;GO:0051536//iron-sulfur cluster binding;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled" GO:0031670//cellular response to nutrient;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter "gi|148683833|gb|EDL15780.1|/0/BRCA1 interacting protein C-terminal helicase 1, isoform CRA_b, partial [Mus musculus]" 170936 2869 0.193333333 0.133333333 -0.5360529 Down 0.148858551 Zfp369 zinc finger protein 369 K12458|1|0.0|1707|mmu:170936|zinc finger protein 274 GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0005165//neurotrophin receptor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0012501//programmed cell death;GO:0070997//neuron death;GO:0007254//JNK cascade;GO:0007049//cell cycle;GO:0044764;GO:0006351//transcription, DNA-templated" gi|154350211|ref|NP_848141.3|/0/neurotrophin receptor-interacting factor 2 [Mus musculus] 208777 4474 0.14 0.203333333 0.538419915 Up 0.148858551 Sned1 "sushi, nidogen and EGF-like domains 1" K02599|1|9e-178|627|bfo:BRAFLDRAFT_107492|Notch - GO:0046872//metal ion binding GO:0031589//cell-substrate adhesion "gi|153791169|ref|NP_766051.4|/0/sushi, nidogen and EGF-like domain-containing protein 1 precursor [Mus musculus]" 71999 2117 21.39666667 22.00333333 0.040336037 Up 0.148839746 Fbxo22 F-box protein 22 K10302|1|0.0|785|mmu:71999|F-box protein 22 GO:0043231//intracellular membrane-bounded organelle;GO:0031674//I band GO:0019787//ubiquitin-like protein transferase activity;GO:0005488//binding GO:0048641//regulation of skeletal muscle tissue development;GO:0031398//positive regulation of protein ubiquitination;GO:0014902//myotube differentiation;GO:0031331;GO:0019941//modification-dependent protein catabolic process;GO:0033554//cellular response to stress;GO:0051169//nuclear transport gi|139948465|ref|NP_082325.2|/0/F-box only protein 22 [Mus musculus] 14422 4086 0.37 0.296666667 -0.318682435 Down 0.148811539 B4galnt2 "beta-1,4-N-acetyl-galactosaminyl transferase 2" "K09655|1|0.0|1005|mmu:14422|beta-1,4-N-acetylgalactosaminyltransferase 2 [EC:2.4.1.-]" GO:0031228//intrinsic component of Golgi membrane GO:0008194//UDP-glycosyltransferase activity GO:0006464//cellular protein modification process;GO:0006040//amino sugar metabolic process;GO:0007162//negative regulation of cell adhesion;GO:0030258//lipid modification "gi|6679931|ref|NP_032107.1|/0/beta-1,4 N-acetylgalactosaminyltransferase 2 [Mus musculus]" 22114 1466 0.283333333 0.353333333 0.318529518 Up 0.148811539 Tssk1 testis-specific serine kinase 1 K08811|1|0.0|709|mmu:22114|testis-specific serine kinase [EC:2.7.11.1] GO:0030141//secretory granule;GO:0005929//cilium GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding GO:0006464//cellular protein modification process;GO:0048232//male gamete generation;GO:0006796//phosphate-containing compound metabolic process;GO:0007281//germ cell development gi|112734851|ref|NP_033461.2|/0/testis-specific serine/threonine-protein kinase 1 [Mus musculus] 72140 2567 6.55 6.303333333 -0.055379949 Down 0.148783331 Cep89 centrosomal protein 89 K16543|1|0.0|1394|mmu:72140|centrosomal protein CEP89 GO:0005815//microtubule organizing center;GO:0016020//membrane GO:0005488//binding - gi|13386288|ref|NP_082396.1|/0/centrosomal protein of 89 kDa [Mus musculus] 66352 4004.63 5.69 5.44 -0.064822001 Down 0.148783331 Blzf1 basic leucine zipper nuclear factor 1 - GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0044389//ubiquitin-like protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding GO:0006886//intracellular protein transport;GO:0006996//organelle organization;GO:0006886//intracellular protein transport;GO:0006996//organelle organization;GO:0006886//intracellular protein transport;GO:0006996//organelle organization gi|31541835|ref|NP_079781.2|/0/golgin-45 isoform a [Mus musculus] 106064 5094 5.36 5.606666667 0.064910299 Up 0.148783331 AW549877 expressed sequence AW549877 K05080|1|2e-78|297|bom:102268311|growth hormone receptor;K10291|4|5e-18|97.1|tgu:100220386|F-box protein 4 - - - gi|672041570|ref|XP_008758992.1|/5.09641e-151/PREDICTED: UPF0600 protein C5orf51 homolog isoform X1 [Rattus norvegicus] 102098 5300 5.866666667 5.616666667 -0.062826837 Down 0.148783331 Arhgef18 rho/rac guanine nucleotide exchange factor (GEF) 18 K16529|1|8e-144|514|acs:100568036|A-kinase anchor protein 13 - - - gi|148689955|gb|EDL21902.1|/0/rho/rac guanine nucleotide exchange factor (GEF) 18 [Mus musculus] 667335 733 0.143333333 0.206666667 0.527931556 Up 0.148642296 Gm8579 spermatogenesis associated glutamate (E)-rich protein 4a pseudogene - - - - - 11444 5405 0.183333333 0.126666667 -0.5334322 Down 0.148642296 Chrnb2 "cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)" K04813|1|0.0|937|mmu:11444|nicotinic acetylcholine receptor beta-2 GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0097060//synaptic membrane GO:0042165//neurotransmitter binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004888//transmembrane signaling receptor activity "GO:0014046;GO:0007631//feeding behavior;GO:0030534//adult behavior;GO:0007416//synapse assembly;GO:0050954//sensory perception of mechanical stimulus;GO:0070838//divalent metal ion transport;GO:0014070//response to organic cyclic compound;GO:0021794//thalamus development;GO:0001508//action potential;GO:0051705;GO:0001963//synaptic transmission, dopaminergic;GO:0042748//circadian sleep/wake cycle, non-REM sleep;GO:0007274//neuromuscular synaptic transmission;GO:0050953//sensory perception of light stimulus;GO:0007612//learning;GO:0010646//regulation of cell communication;GO:0006936//muscle contraction;GO:0042747//circadian sleep/wake cycle, REM sleep;GO:0030888//regulation of B cell proliferation;GO:0021554//optic nerve development;GO:0007632//visual behavior;GO:0051259//protein oligomerization;GO:0006950//response to stress;GO:0021955//central nervous system neuron axonogenesis;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0042069//regulation of catecholamine metabolic process;GO:0097305//response to alcohol" gi|31542397|ref|NP_033732.2|/0/neuronal acetylcholine receptor subunit beta-2 precursor [Mus musculus] 268420 6025 23.82666667 23.22666667 -0.03679501 Down 0.148576479 Alkbh5 "alkB homolog 5, RNA demethylase" K10767|1|0.0|727|mmu:268420|alkylated DNA repair protein alkB homolog 5 [EC:1.14.11.-] - - - - 74414 1796 24.29 23.68666667 -0.036287302 Down 0.148576479 Polr3c polymerase (RNA) III (DNA directed) polypeptide C K03023|1|0.0|1026|mmu:74414|DNA-directed RNA polymerase III subunit RPC3 GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity GO:0031349//positive regulation of defense response;GO:0032481//positive regulation of type I interferon production;GO:0002252;GO:0010467//gene expression gi|198278473|ref|NP_083201.1|/0/DNA-directed RNA polymerase III subunit RPC3 [Mus musculus] 103963 3642 20.97333333 20.37666667 -0.041638104 Down 0.148576479 Rpn1 ribophorin I K12666|1|0.0|1152|mmu:103963|oligosaccharyltransferase complex subunit alpha (ribophorin I) GO:0031224//intrinsic component of membrane;GO:0048770;GO:0005789//endoplasmic reticulum membrane GO:0004576//oligosaccharyl transferase activity GO:0042886//amide transport;GO:0006613//cotranslational protein targeting to membrane;GO:0010467//gene expression;GO:0006487//protein N-linked glycosylation gi|282398108|ref|NP_598694.3|/0/dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 precursor [Mus musculus] 54170 2621 21.67 22.26666667 0.039186449 Up 0.148576479 Rragc Ras-related GTP binding C K16186|1|0.0|726|rno:298514|Ras-related GTP-binding protein C/D GO:0000323//lytic vacuole GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0046983//protein dimerization activity GO:0009154//purine ribonucleotide catabolic process gi|532019221|ref|XP_005353335.1|/0/PREDICTED: ras-related GTP-binding protein C [Microtus ochrogaster] 67563 2555 23.35 22.75333333 -0.037344636 Down 0.148576479 Narfl nuclear prelamin A recognition factor-like K01069|1|2e-23|113|mmu:68977|hydroxyacylglutathione hydrolase [EC:3.1.2.6];K16608|4|3e-17|93.2|myd:102767985|tubulin monoglycylase TTLL3/8 [EC:6.3.2.-] GO:0043234//protein complex GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding "GO:0033483;GO:0006351//transcription, DNA-templated;GO:0006950//response to stress" gi|254911120|ref|NP_080514.3|/0/cytosolic Fe-S cluster assembly factor NARFL [Mus musculus] 15982 1836 24.08666667 23.49 -0.036188041 Down 0.148576479 Ifrd1 interferon-related developmental regulator 1 "K13855|1|8e-180|632|tup:102497672|solute carrier family 4 (anion exchanger), member 2" GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane - GO:0048699//generation of neurons;GO:0008283//cell proliferation;GO:0007525//somatic muscle development;GO:0001709//cell fate determination gi|226062273|ref|NP_038590.2|/0/interferon-related developmental regulator 1 [Mus musculus] 14701 4216.75 9.543333333 9.2 -0.052859403 Down 0.148510662 Gng12 "guanine nucleotide binding protein (G protein), gamma 12" K04347|1|2e-31|141|mmu:14701|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0015629//actin cytoskeleton;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0015629//actin cytoskeleton;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0015629//actin cytoskeleton;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0015629//actin cytoskeleton;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0015629//actin cytoskeleton;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0015629//actin cytoskeleton GO:0043168//anion binding;GO:0060089;GO:0043168//anion binding;GO:0060089;GO:0043168//anion binding;GO:0060089;GO:0043168//anion binding;GO:0060089;GO:0043168//anion binding;GO:0060089;GO:0043168//anion binding;GO:0060089 GO:0007267//cell-cell signaling;GO:0033762//response to glucagon;GO:0007166//cell surface receptor signaling pathway;GO:0015980//energy derivation by oxidation of organic compounds;GO:0002237//response to molecule of bacterial origin;GO:0007267//cell-cell signaling;GO:0033762//response to glucagon;GO:0007166//cell surface receptor signaling pathway;GO:0015980//energy derivation by oxidation of organic compounds;GO:0002237//response to molecule of bacterial origin;GO:0007267//cell-cell signaling;GO:0033762//response to glucagon;GO:0007166//cell surface receptor signaling pathway;GO:0015980//energy derivation by oxidation of organic compounds;GO:0002237//response to molecule of bacterial origin;GO:0007267//cell-cell signaling;GO:0033762//response to glucagon;GO:0007166//cell surface receptor signaling pathway;GO:0015980//energy derivation by oxidation of organic compounds;GO:0002237//response to molecule of bacterial origin;GO:0007267//cell-cell signaling;GO:0033762//response to glucagon;GO:0007166//cell surface receptor signaling pathway;GO:0015980//energy derivation by oxidation of organic compounds;GO:0002237//response to molecule of bacterial origin;GO:0007267//cell-cell signaling;GO:0033762//response to glucagon;GO:0007166//cell surface receptor signaling pathway;GO:0015980//energy derivation by oxidation of organic compounds;GO:0002237//response to molecule of bacterial origin gi|13384618|ref|NP_079554.1|/1.62621e-30/guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [Mus musculus] 67759 843 9.716666667 10.06 0.050096922 Up 0.148510662 Plgrkt "plasminogen receptor, C-terminal lysine transmembrane protein" - GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane - GO:0010755//regulation of plasminogen activation;GO:0006952//defense response;GO:0042221//response to chemical gi|21312800|ref|NP_080638.1|/1.96259e-76/plasminogen receptor (KT) [Mus musculus] 18631 879 9.216666667 9.56 0.052765544 Up 0.148510662 Pex11a peroxisomal biogenesis factor 11 alpha K13351|1|5e-118|426|mmu:18631|peroxin-11A GO:0031231//intrinsic component of peroxisomal membrane;GO:0032991//macromolecular complex GO:0042802//identical protein binding GO:0045444//fat cell differentiation;GO:0007031//peroxisome organization;GO:0007154//cell communication;GO:0032535//regulation of cellular component size "gi|148675102|gb|EDL07049.1|/8.80327e-131/peroxisomal biogenesis factor 11a, isoform CRA_b, partial [Mus musculus]" 71678 3457 10.84333333 10.50333333 -0.045961068 Down 0.148510662 Brox BRO1 domain and CAAX motif containing K12200|1|3e-11|73.9|lgi:LOTGIDRAFT_207048|programmed cell death 6-interacting protein;K18040|3|5e-08|63.2|hst:105189163|tyrosine-protein phosphatase non-receptor type 23 [EC:3.1.3.48] - - - gi|58037255|ref|NP_082137.1|/0/BRO1 domain-containing protein BROX [Mus musculus] 23834 4608 0.186666667 0.13 -0.521952703 Down 0.148397834 Cdc6 cell division cycle 6 K02213|1|0.0|1066|mmu:23834|cell division control protein 6 GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle GO:0032550;GO:0019899//enzyme binding;GO:0016462//pyrophosphatase activity;GO:0032550;GO:0019899//enzyme binding;GO:0016462//pyrophosphatase activity GO:0006259//DNA metabolic process;GO:0007088//regulation of mitotic nuclear division;GO:0007059//chromosome segregation;GO:0032467//positive regulation of cytokinesis;GO:0006259//DNA metabolic process;GO:0007088//regulation of mitotic nuclear division;GO:0007059//chromosome segregation;GO:0032467//positive regulation of cytokinesis gi|6753368|ref|NP_035929.1|/0/cell division control protein 6 homolog isoform a [Mus musculus] 15566 3095 0.19 0.133333333 -0.510961919 Down 0.148397834 Htr7 5-hydroxytryptamine (serotonin) receptor 7 K04163|1|0.0|862|mmu:15566|5-hydroxytryptamine receptor 7 GO:0044297//cell body;GO:0031224//intrinsic component of membrane;GO:0033267;GO:0005783//endoplasmic reticulum;GO:0030136//clathrin-coated vesicle GO:0008227//G-protein coupled amine receptor activity "GO:0007611//learning or memory;GO:0014848;GO:0003014//renal system process;GO:0048167//regulation of synaptic plasticity;GO:0010975//regulation of neuron projection development;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0051384//response to glucocorticoid;GO:0046058//cAMP metabolic process;GO:0009628//response to abiotic stimulus;GO:0019233//sensory perception of pain;GO:0050880//regulation of blood vessel size;GO:0042320//regulation of circadian sleep/wake cycle, REM sleep;GO:0001820//serotonin secretion" gi|113865998|ref|NP_032341.2|/0/5-hydroxytryptamine receptor 7 [Mus musculus] 73451 3385 0.606666667 0.696666667 0.199564492 Up 0.148388431 Zfp763 zinc finger protein 763 K09228|1|0.0|1281|mmu:73451|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|58037331|ref|NP_082819.1|/0/zinc finger protein 763 [Mus musculus] 140571 6024 0.666666667 0.58 -0.200912694 Down 0.148388431 Plxnb3 plexin B3 K06821|1|0.0|3553|mmu:140571|plexin B GO:0044464;GO:0031224//intrinsic component of membrane - GO:0048731//system development;GO:0007154//cell communication gi|125347785|ref|NP_062533.2|/0/plexin-B3 precursor [Mus musculus] 16182 4158 0.466666667 0.55 0.237039197 Up 0.148350822 Il18r1 interleukin 18 receptor 1 K05173|1|0.0|712|mmu:16182|interleukin 18 receptor 1 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004896//cytokine receptor activity;GO:0004896//cytokine receptor activity;GO:0004896//cytokine receptor activity GO:0042088//T-helper 1 type immune response;GO:0046649//lymphocyte activation;GO:0019221//cytokine-mediated signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0006952//defense response;GO:0042088//T-helper 1 type immune response;GO:0046649//lymphocyte activation;GO:0019221//cytokine-mediated signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0006952//defense response;GO:0042088//T-helper 1 type immune response;GO:0046649//lymphocyte activation;GO:0019221//cytokine-mediated signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0006952//defense response gi|240255489|ref|NP_001155314.1|/0/interleukin-18 receptor 1 isoform b precursor [Mus musculus] 52906 4885 0.433333333 0.51 0.23502003 Up 0.148350822 Ahi1 Abelson helper integration site 1 K16740|1|0.0|1857|rno:308923|jouberin GO:0070161;GO:0035869//ciliary transition zone;GO:0005813//centrosome;GO:0070161;GO:0035869//ciliary transition zone;GO:0005813//centrosome - GO:0034613//cellular protein localization;GO:0002090//regulation of receptor internalization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0030858//positive regulation of epithelial cell differentiation;GO:0007610//behavior;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007420//brain development;GO:0003143//embryonic heart tube morphogenesis;GO:0009798//axis specification;GO:0048858//cell projection morphogenesis;GO:0039007;GO:0010927;GO:0003407//neural retina development;GO:0039022//pronephric duct development;GO:0034613//cellular protein localization;GO:0002090//regulation of receptor internalization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0030858//positive regulation of epithelial cell differentiation;GO:0007610//behavior;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007420//brain development;GO:0003143//embryonic heart tube morphogenesis;GO:0009798//axis specification;GO:0048858//cell projection morphogenesis;GO:0039007;GO:0010927;GO:0003407//neural retina development;GO:0039022//pronephric duct development gi|171906571|ref|NP_080479.2|/0/jouberin isoform 1 [Mus musculus] 12145 2636 0.503333333 0.426666667 -0.238404739 Down 0.148350822 Cxcr5 chemokine (C-X-C motif) receptor 5 K04190|1|0.0|717|mmu:12145|C-X-C chemokine receptor type 5 GO:0031224//intrinsic component of membrane GO:0004950//chemokine receptor activity GO:0048534//hematopoietic or lymphoid organ development;GO:0019221//cytokine-mediated signaling pathway;GO:0046649//lymphocyte activation;GO:0051480//regulation of cytosolic calcium ion concentration gi|42475950|ref|NP_031577.2|/0/C-X-C chemokine receptor type 5 [Mus musculus] 67704 991 24.25333333 23.66333333 -0.035529729 Down 0.148341419 1810037I17Rik RIKEN cDNA 1810037I17 gene - - - - - 14133 1317 1.963333333 2.1 0.097084195 Up 0.148341419 Fcna ficolin A K10104|1|0.0|672|mmu:14133|ficolin GO:0005578//proteinaceous extracellular matrix GO:0043169//cation binding GO:0006952//defense response gi|6679763|ref|NP_032021.1|/0/ficolin-1 precursor [Mus musculus] 69136 1364 1.866666667 2.003333333 0.101938164 Up 0.148341419 Tusc1 tumor suppressor candidate 1 - - - - gi|51890207|ref|NP_081230.1|/3.37026e-65/tumor suppressor candidate gene 1 protein homolog [Mus musculus] 16978 2725.54 22.35333333 21.76 -0.038811426 Down 0.148341419 Lrrfip1 leucine rich repeat (in FLII) interacting protein 1 K17785|1|3e-151|538|hgl:101700543|mitofilin;K17570|2|4e-15|86.7|smm:Smp_175460|hydrocephalus-inducing protein;K17751|3|7e-13|79.0|api:100167379|myosin heavy chain 6/7 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding "GO:0006351//transcription, DNA-templated" gi|894216300|ref|NP_001297661.1|/0/leucine-rich repeat flightless-interacting protein 1 isoform 4 [Mus musculus] 320394 1767 2.02 1.88 -0.103622631 Down 0.148341419 Cenpt centromere protein T K11512|1|0.0|885|mmu:320394|centromere protein T GO:0000776//kinetochore;GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0046983//protein dimerization activity GO:0034508//centromere complex assembly;GO:0000087//mitotic M phase gi|28893125|ref|NP_796124.1|/0/centromere protein T [Mus musculus] 66237 1514 1.896666667 2.036666667 0.102743728 Up 0.148341419 Atp6v1g2 "ATPase, H+ transporting, lysosomal V1 subunit G2" K02152|1|4e-30|135|mmu:66237|V-type H+-transporting ATPase subunit G GO:0005774//vacuolar membrane;GO:0030672//synaptic vesicle membrane GO:0019829//cation-transporting ATPase activity "GO:0006818//hydrogen transport;GO:0015031//protein transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006996//organelle organization;GO:0009154//purine ribonucleotide catabolic process;GO:0006811//ion transport;GO:0044403//symbiosis, encompassing mutualism through parasitism;GO:0006875//cellular metal ion homeostasis" gi|511923809|ref|XP_004781065.1|/5.31215e-30/PREDICTED: V-type proton ATPase subunit G 2 isoform X2 [Mustela putorius furo] 210004 2866 1.94 2.076666667 0.09821301 Up 0.148341419 B3gntl1 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1" K14529|1|1e-101|373|cin:100177615|ribonuclease P protein subunit RPP14 [EC:3.1.26.5] - GO:0016740//transferase activity - "gi|148702899|gb|EDL34846.1|/0/RIKEN cDNA 6030413G23, isoform CRA_c, partial [Mus musculus]" 68108 2994.47 1.993333333 2.136666667 0.100178872 Up 0.148341419 Snhg17 small nucleolar RNA host gene 17 - - - - - 504193 4701.86 2.05 1.913333333 -0.099535674 Down 0.148341419 Npcd neuronal pentraxin chromo domain K11453|1|6e-119|432|amj:102562598|chromobox protein 6 GO:0016020//membrane GO:0005515//protein binding;GO:0001847//opsonin receptor activity - gi|113374171|ref|NP_001013380.2|/0/neuronal pentraxin with chromo domain isoform 2 [Mus musculus] 23857 3628.65 3.246666667 3.073333333 -0.079155022 Down 0.148172176 Dmtf1 cyclin D binding myb-like transcription factor 1 K15225|1|7e-28|129|asn:102385533|transcription termination factor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen GO:0005488//binding;GO:0003676//nucleic acid binding "GO:0044763;GO:0006351//transcription, DNA-templated;GO:0044763;GO:0006351//transcription, DNA-templated" "gi|148682742|gb|EDL14689.1|/0/cyclin D binding myb-like transcription factor 1, isoform CRA_b, partial [Mus musculus]" 12890 4928 2.78 2.946666667 0.083998986 Up 0.148172176 Cplx2 complexin 2 K15294|1|4e-42|177|gja:107109491|complexin-1/2 GO:0043005//neuron projection;GO:0044297//cell body;GO:0031201//SNARE complex GO:0019905//syntaxin binding GO:0006887//exocytosis;GO:0048167//regulation of synaptic plasticity gi|927191125|ref|XP_013929381.1|/3.1908e-41/PREDICTED: complexin-2 [Thamnophis sirtalis] 666945 1362 3.103333333 2.936666667 -0.079639149 Down 0.148172176 Gm10638 predicted gene 10638 - - - - gi|74221528|dbj|BAE21488.1|/8.79949e-82/unnamed protein product [Mus musculus] 19746 1530 2.986666667 2.82 -0.082841069 Down 0.148172176 Rhd "Rh blood group, D antigen" K06579|1|0.0|753|mmu:19746|Rhesus blood group glycoprotein GO:0031224//intrinsic component of membrane GO:0008509//anion transmembrane transporter activity GO:0015696//ammonium transport gi|227116310|ref|NP_035400.3|/0/blood group Rh(D) polypeptide [Mus musculus] 27053 1927 1.026666667 1.133333333 0.142604395 Up 0.148162774 Asns asparagine synthetase K01953|1|0.0|1079|mmu:27053|asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] GO:0044444//cytoplasmic part "GO:0032550;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0042802//identical protein binding" GO:0034698//response to gonadotropin;GO:0000278//mitotic cell cycle;GO:0010243//response to organonitrogen compound;GO:0006915//apoptotic process;GO:0006529//asparagine biosynthetic process;GO:0009064//glutamine family amino acid metabolic process;GO:0001101//response to acid chemical;GO:0009314//response to radiation;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0009267//cellular response to starvation gi|33469123|ref|NP_036185.1|/0/asparagine synthetase [glutamine-hydrolyzing] [Mus musculus] 218461 4619 1.26 1.146666667 -0.13597767 Down 0.148162774 Pde8b phosphodiesterase 8B "K18437|1|0.0|1439|ngi:103752265|high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]" - - - "gi|282165812|ref|NP_001164140.1|/0/high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform 1 [Mus musculus]" 68938 1827.71 19.85333333 19.27666667 -0.042525652 Down 0.148078153 Aspscr1 "alveolar soft part sarcoma chromosome region, candidate 1 (human)" K15627|1|0.0|890|mmu:68938|tether containing UBX domain for GLUT4 GO:0012505//endomembrane system;GO:0044459;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system;GO:0044459;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system;GO:0044459;GO:0044444//cytoplasmic part - GO:0010827//regulation of glucose transport;GO:0033500//carbohydrate homeostasis;GO:0015031//protein transport;GO:0010827//regulation of glucose transport;GO:0033500//carbohydrate homeostasis;GO:0015031//protein transport;GO:0010827//regulation of glucose transport;GO:0033500//carbohydrate homeostasis;GO:0015031//protein transport "gi|148702838|gb|EDL34785.1|/0/alveolar soft part sarcoma chromosome region, candidate 1 (human), isoform CRA_a, partial [Mus musculus]" 12177 3237 19.43666667 18.86 -0.043451146 Down 0.148078153 Bnip3l BCL2/adenovirus E1B interacting protein 3-like K15465|1|8e-78|295|nle:100581402|BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like - - - - 268490 1224 21.66 22.24333333 0.03833976 Up 0.148078153 Lsm12 LSM12 homolog - - - - - 74134 2621 0.136666667 0.193333333 0.500428991 Up 0.147955922 Cyp2s1 "cytochrome P450, family 2, subfamily s, polypeptide 1" "K07420|1|0.0|907|mmu:74134|cytochrome P450, family 2, subfamily S, polypeptide 1 [EC:1.14.14.1]" GO:0043231//intracellular membrane-bounded organelle "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0044710 gi|21311915|ref|NP_083051.1|/0/cytochrome P450 2S1 precursor [Mus musculus] 66877 3111 4.126666667 4.33 0.069390116 Up 0.147946519 Crnkl1 "Crn, crooked neck-like 1 (Drosophila)" K12869|1|0.0|1252|rno:100910202|crooked neck GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding "GO:0000398//mRNA splicing, via spliceosome" gi|13385288|ref|NP_080096.1|/0/crooked neck-like protein 1 [Mus musculus] 67378 2972 3.716666667 3.913333333 0.074388698 Up 0.147946519 Bbs2 Bardet-Biedl syndrome 2 (human) K16747|1|0.0|1437|mmu:67378|Bardet-Biedl syndrome 2 protein GO:0005929//cilium;GO:0005815//microtubule organizing center;GO:0043234//protein complex;GO:0031090//organelle membrane - GO:0010467//gene expression;GO:0032099//negative regulation of appetite;GO:0003006//developmental process involved in reproduction;GO:0006886//intracellular protein transport;GO:0021543//pallium development;GO:0019221//cytokine-mediated signaling pathway;GO:0007601//visual perception;GO:0042384//cilium assembly;GO:0014820//tonic smooth muscle contraction;GO:0009887//organ morphogenesis;GO:0030154//cell differentiation;GO:0060295;GO:0035264//multicellular organism growth;GO:0021544//subpallium development;GO:0009725//response to hormone;GO:0050880//regulation of blood vessel size gi|21313344|ref|NP_080392.1|/0/Bardet-Biedl syndrome 2 protein homolog [Mus musculus] 66309 1085 4.26 4.463333333 0.067268124 Up 0.147946519 Tmem128 transmembrane protein 128 - GO:0031224//intrinsic component of membrane - - gi|27228979|ref|NP_079756.2|/8.71748e-92/transmembrane protein 128 [Mus musculus] 70373 4132.08 4.16 3.963333333 -0.069869219 Down 0.147946519 Gpatch2l G patch domain containing 2 like K17569|1|0.0|876|mmu:70373|G patch domain-containing protein 2 - - - gi|37360262|dbj|BAC98109.1|/0/mKIAA1152 protein [Mus musculus] 66929 1599 1.603333333 1.733333333 0.112474729 Up 0.147843093 Asf1b anti-silencing function 1B histone chaperone K10753|1|2e-115|418|mmu:66929|histone chaperone ASF1 GO:0043231//intracellular membrane-bounded organelle;GO:0044427 GO:0005515//protein binding "GO:0006351//transcription, DNA-templated;GO:0034728//nucleosome organization" "gi|148678973|gb|EDL10920.1|/3.98121e-124/ASF1 anti-silencing function 1 homolog B (S. cerevisiae), partial [Mus musculus]" 77574 3738 1.78 1.653333333 -0.106499621 Down 0.147843093 Tcaf1 TRPM8 channel-associated factor 1 K15259|1|2e-30|137|cmy:102945703|poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30] - - - "gi|148681525|gb|EDL13472.1|/0/RIKEN cDNA 3321401G04, isoform CRA_d, partial [Mus musculus]" 20503 2422 1.54 1.666666667 0.114035243 Up 0.147843093 Slc16a7 "solute carrier family 16 (monocarboxylic acid transporters), member 7" "K08184|1|0.0|856|mmu:20503|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 7" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0046943//carboxylic acid transmembrane transporter activity GO:0044763;GO:0046942//carboxylic acid transport gi|6755536|ref|NP_035521.1|/0/monocarboxylate transporter 2 [Mus musculus] 54204 1466 1.62 1.746666667 0.108610498 Up 0.147843093 1-Sep septin 1 K13737|1|0.0|664|mmu:54204|septin 1 GO:0032156//septin cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0032550 GO:0044763 gi|148277024|ref|NP_059489.2|/0/septin-1 [Mus musculus] 232201 3422.96 1.596666667 1.723333333 0.110138625 Up 0.147843093 Arhgap25 Rho GTPase activating protein 25 "K07526|1|5e-27|126|xma:102224175|SLIT-ROBO Rho GTPase activating protein;K12490|5|7e-23|112|tad:TRIADDRAFT_59978|Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3" GO:0044464;GO:0044464;GO:0044464;GO:0044464 GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0008047//enzyme activator activity;GO:0008289//lipid binding GO:0007154//cell communication;GO:0007154//cell communication;GO:0007154//cell communication;GO:0007154//cell communication "gi|148666792|gb|EDK99208.1|/0/Rho GTPase activating protein 25, isoform CRA_a, partial [Mus musculus]" 668171 7005 1.64 1.773333333 0.11276793 Up 0.147843093 Zxda "zinc finger, X-linked, duplicated A" K10485|1|9e-79|299|myd:102773583|BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1) GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|74205681|dbj|BAE21123.1|/0/unnamed protein product [Mus musculus] 12751 3573 21.27333333 21.84666667 0.038367064 Up 0.147814886 Tpp1 tripeptidyl peptidase I K01279|1|0.0|1093|mmu:12751|tripeptidyl-peptidase I [EC:3.4.14.9] - - - - 56085 3644.18 23.15666667 22.58333333 -0.036169151 Down 0.147814886 Ubqln1 ubiquilin 1 K04523|1|0.0|856|mmu:56085|ubiquilin GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex GO:0032403//protein complex binding;GO:0019899//enzyme binding;GO:0032403//protein complex binding;GO:0019899//enzyme binding GO:0006950//response to stress;GO:0016567//protein ubiquitination;GO:0012501//programmed cell death;GO:0006950//response to stress;GO:0016567//protein ubiquitination;GO:0012501//programmed cell death gi|22726191|ref|NP_689420.1|/0/ubiquilin-1 isoform 2 [Mus musculus] 52027 565 0.206666667 0.146666667 -0.494764692 Down 0.147805483 D17Ertd648e "DNA segment, Chr 17, ERATO Doi 648, expressed" - - - - - 229937 2813 2.436666667 2.29 -0.089561307 Down 0.147739667 Znhit6 "zinc finger, HIT type 6" - GO:0030529//intracellular ribonucleoprotein complex GO:0005515//protein binding;GO:0043169//cation binding GO:0000491//small nucleolar ribonucleoprotein complex assembly gi|124487366|ref|NP_001074563.1|/0/box C/D snoRNA protein 1 [Mus musculus] 71983 1815 2.386666667 2.536666667 0.087936866 Up 0.147739667 Tmco6 transmembrane and coiled-coil domains 6 - - - - gi|112181164|ref|NP_082312.3|/0/transmembrane and coiled-coil domain-containing protein 6 [Mus musculus] 434232 2026 2.303333333 2.45 0.089058539 Up 0.147739667 Iqck IQ motif containing K - - - - gi|124517720|ref|NP_001074915.1|/1.71971e-154/IQ domain-containing protein K [Mus musculus] 67042 1050 8.6 8.926666667 0.053784895 Up 0.14771146 Ift27 intraflagellar transport 27 K07934|1|1e-102|375|mmu:67042|intraflagellar transport protein 27 - - - - 14284 5886 8.94 8.606666667 -0.054820237 Down 0.14771146 Fosl2 fos-like antigen 2 K09030|1|3e-132|476|mmu:14284|fos-like antigen 2 GO:0031981//nuclear lumen GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0043566//structure-specific DNA binding GO:0044703;GO:0048511//rhythmic process;GO:0009605//response to external stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0044707;GO:0046683//response to organophosphorus;GO:0043627//response to estrogen;GO:0008284//positive regulation of cell proliferation;GO:0009416//response to light stimulus;GO:0044767//single-organism developmental process;GO:0006950//response to stress;GO:0007631//feeding behavior gi|34328117|ref|NP_032063.2|/2.35069e-131/fos-related antigen 2 [Mus musculus] 18567 1121 9.83 10.16333333 0.048110328 Up 0.14771146 Pdcd2 programmed cell death 2 K14801|1|0.0|678|mmu:18567|pre-rRNA-processing protein TSR4 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0012501//programmed cell death gi|120407033|ref|NP_032825.2|/0/programmed cell death protein 2 [Mus musculus] 67949 1894 9.053333333 8.72 -0.054120939 Down 0.14771146 Nifk nucleolar protein interacting with the FHA domain of MKI67 K14838|1|6e-148|526|mmu:67949|nucleolar protein 15 GO:0000228//nuclear chromosome GO:0003676//nucleic acid binding GO:0010921//regulation of phosphatase activity gi|224809384|ref|NP_080748.3|/5.41744e-147/MKI67 FHA domain-interacting nucleolar phosphoprotein [Mus musculus] 104112 4437.97 10.21 9.876666667 -0.047886741 Down 0.14771146 Acly ATP citrate lyase K01648|1|0.0|2135|mmu:104112|ATP citrate (pro-S)-lyase [EC:2.3.3.8] GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0031981//nuclear lumen;GO:0016020//membrane "GO:0004774//succinate-CoA ligase activity;GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer;GO:0043169//cation binding;GO:0032550;GO:0004774//succinate-CoA ligase activity;GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer;GO:0043169//cation binding;GO:0032550" GO:0006631//fatty acid metabolic process;GO:0006084//acetyl-CoA metabolic process;GO:0005975//carbohydrate metabolic process;GO:0072350//tricarboxylic acid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006084//acetyl-CoA metabolic process;GO:0005975//carbohydrate metabolic process;GO:0072350//tricarboxylic acid metabolic process gi|313151222|ref|NP_001186225.1|/0/ATP-citrate synthase isoform 1 [Mus musculus] 16886 4641.57 8.453333333 8.78 0.0547006 Up 0.14771146 Limk2 LIM motif-containing protein kinase 2 K05744|1|0.0|1114|cge:100760910|LIM domain kinase 2 [EC:2.7.11.1] - - - - 80509 1877.78 9.71 9.38 -0.049883373 Down 0.14771146 Med8 mediator complex subunit 8 K15129|1|3e-96|355|mmu:80509|mediator of RNA polymerase II transcription subunit 8 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043234//protein complex "GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" "GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated" gi|114155155|ref|NP_064384.2|/1.813e-126/mediator of RNA polymerase II transcription subunit 8 isoform 1 [Mus musculus] 97165 2692 5.196666667 5.433333333 0.064251036 Up 0.147645643 Hmgb2 high mobility group box 2 K11295|1|1e-107|354|cge:100762338|high mobility group protein B2 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome;GO:0044421;GO:0044444//cytoplasmic part GO:0042393//histone binding;GO:0005102//receptor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding GO:0032496//response to lipopolysaccharide;GO:0051099//positive regulation of binding;GO:0006366//transcription from RNA polymerase II promoter;GO:0030219//megakaryocyte differentiation;GO:0001935//endothelial cell proliferation;GO:0008406//gonad development;GO:0006915//apoptotic process;GO:0032069;GO:0006284//base-excision repair;GO:0030218//erythrocyte differentiation;GO:0006935//chemotaxis;GO:0006997//nucleus organization;GO:0048232//male gamete generation;GO:0009725//response to hormone gi|625292335|ref|XP_007637920.1|/1.07226e-106/PREDICTED: high mobility group protein B2 isoform X2 [Cricetulus griseus] 269401 5390 5.853333333 5.61 -0.061257668 Down 0.147645643 Zfp512b zinc finger protein 512B K00876|1|0.0|939|myb:102264222|uridine kinase [EC:2.7.1.48];K15200|2|3e-32|144|bfo:BRAFLDRAFT_111367|general transcription factor 3C polypeptide 2;K00907|4|6e-15|87.0|ecb:100070482|myosin-light-chain kinase [EC:2.7.11.18] - - - gi|37360280|dbj|BAC98118.1|/0/mKIAA1196 protein [Mus musculus] 83813 3220 5.78 6.023333333 0.059492608 Up 0.147645643 Tnk1 "tyrosine kinase, non-receptor, 1" K08885|1|0.0|1220|mmu:83813|non-receptor tyrosine-protein kinase TNK1 [EC:2.7.10.2] GO:0044444//cytoplasmic part GO:0032550;GO:0004713//protein tyrosine kinase activity GO:0007265//Ras protein signal transduction;GO:0006468//protein phosphorylation;GO:0016049//cell growth gi|264681505|ref|NP_114086.3|/0/non-receptor tyrosine-protein kinase TNK1 [Mus musculus] 235283 2814 5.586666667 5.343333333 -0.064247724 Down 0.147645643 Gramd1b GRAM domain containing 1B K19951|1|1e-09|68.6|hst:105189441|TBC1 domain family member 9 - - - gi|27777683|ref|NP_766356.1|/0/GRAM domain-containing protein 1B [Mus musculus] 76089 6510 5.816666667 5.573333333 -0.061652189 Down 0.147645643 Rapgef2 Rap guanine nucleotide exchange factor (GEF) 2 K08018|1|0.0|2612|mmu:76089|Rap guanine nucleotide exchange factor 2 - - - "gi|44890797|gb|AAH67056.1|/0/Rapgef2 protein, partial [Mus musculus]" 27965 2690 5.423333333 5.66 0.061622208 Up 0.147645643 Spg21 spastic paraplegia 21 homolog (human) K19367|1|4e-171|604|mmu:27965|maspardin GO:0005798//Golgi-associated vesicle;GO:0031090//organelle membrane GO:0005102//receptor binding GO:0002429//immune response-activating cell surface receptor signaling pathway gi|20070390|ref|NP_613050.1|/3.13624e-170/maspardin [Mus musculus] 22232 2426 6.096666667 6.34 0.056462171 Up 0.147645643 Slc35a2 "solute carrier family 35 (UDP-galactose transporter), member A2" "K15272|1|0.0|646|mmu:22232|solute carrier family 35 (UDP-sugar transporter), member A1/2/3" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system GO:0015165//pyrimidine nucleotide-sugar transmembrane transporter activity;GO:0005402//cation:sugar symporter activity;GO:0015165//pyrimidine nucleotide-sugar transmembrane transporter activity;GO:0005402//cation:sugar symporter activity GO:0044763;GO:0019318//hexose metabolic process;GO:0015711//organic anion transport;GO:0006862//nucleotide transport;GO:0044763;GO:0019318//hexose metabolic process;GO:0015711//organic anion transport;GO:0006862//nucleotide transport gi|74212964|dbj|BAE33420.1|/0/unnamed protein product [Mus musculus] 227638 3852.74 5.963333333 6.203333333 0.056924668 Up 0.147645643 Qsox2 quiescin Q6 sulfhydryl oxidase 2 K10758|1|0.0|1022|mmu:227638|thiol oxidase [EC:1.8.3.2] GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane "GO:0016670//oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor;GO:0016670//oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor" GO:0044710;GO:0019725//cellular homeostasis;GO:0044710;GO:0019725//cellular homeostasis gi|729719225|ref|NP_001289885.1|/0/sulfhydryl oxidase 2 isoform 1 [Mus musculus] 76867 3533 5.23 5.47 0.064729887 Up 0.147645643 Rhbdd1 rhomboid domain containing 1 K09651|1|0.0|665|mmu:76867|rhomboid domain-containing protein 1 [EC:3.4.21.-] GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0004175//endopeptidase activity;GO:0005488//binding;GO:0004175//endopeptidase activity;GO:0005488//binding GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0003006//developmental process involved in reproduction;GO:0006915//apoptotic process;GO:0009411//response to UV;GO:0016485//protein processing;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006464//cellular protein modification process;GO:0002176//male germ cell proliferation;GO:0009896;GO:0046903//secretion;GO:0006986//response to unfolded protein;GO:0033619//membrane protein proteolysis;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0003006//developmental process involved in reproduction;GO:0006915//apoptotic process;GO:0009411//response to UV;GO:0016485//protein processing;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006464//cellular protein modification process;GO:0002176//male germ cell proliferation;GO:0009896;GO:0046903//secretion;GO:0006986//response to unfolded protein;GO:0033619//membrane protein proteolysis gi|170014730|ref|NP_084053.3|/0/rhomboid-related protein 4 [Mus musculus] 53319 3097.27 19.05666667 18.49666667 -0.043030487 Down 0.147589229 Nxf1 nuclear RNA export factor 1 K14284|1|0.0|1022|ngi:103737663|nuclear RNA export factor GO:0016604//nuclear body;GO:0016234//inclusion body;GO:0044444//cytoplasmic part;GO:0005635//nuclear envelope;GO:0016604//nuclear body;GO:0016234//inclusion body;GO:0044444//cytoplasmic part;GO:0005635//nuclear envelope GO:0003723//RNA binding;GO:0005215//transporter activity;GO:0036094//small molecule binding;GO:0003723//RNA binding;GO:0005215//transporter activity;GO:0036094//small molecule binding GO:0043170;GO:0006406//mRNA export from nucleus;GO:0043170;GO:0006406//mRNA export from nucleus "gi|148701415|gb|EDL33362.1|/0/nuclear RNA export factor 1 homolog (S. cerevisiae), isoform CRA_a, partial [Mus musculus]" 52585 1486 22.12666667 21.56333333 -0.037205917 Down 0.147589229 Dhrs1 dehydrogenase/reductase (SDR family) member 1 K11163|1|0.0|635|mmu:52585|dehydrogenase/reductase SDR family member 1 [EC:1.1.-.-] GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0036094//small molecule binding;GO:0003824//catalytic activity GO:0044710 gi|31980844|ref|NP_081095.2|/6.05751e-180/dehydrogenase/reductase SDR family member 1 [Mus musculus] 54384 3446 0.65 0.743333333 0.193569586 Up 0.147504607 Mtmr7 myotubularin related protein 7 K18083|1|0.0|1316|mmu:54384|myotubularin-related protein 6/7/8 [EC:3.1.3.64 3.1.3.95] GO:0044444//cytoplasmic part GO:0004721//phosphoprotein phosphatase activity GO:0006470//protein dephosphorylation;GO:0046488//phosphatidylinositol metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0046838//phosphorylated carbohydrate dephosphorylation gi|103472017|ref|NP_001035789.1|/0/myotubularin-related protein 7 [Mus musculus] 12223 2876 0.656666667 0.746666667 0.185303103 Up 0.147504607 Btc "betacellulin, epidermal growth factor family member" K09783|1|3e-61|239|mmu:12223|betacellulin - - - - 12477 1933 0.68 0.773333333 0.185555653 Up 0.147504607 Ctla4 cytotoxic T-lymphocyte-associated protein 4 K06538|1|3e-127|458|mmu:12477|cytotoxic T-lymphocyte-associated protein 4 GO:0009986//cell surface;GO:0030139//endocytic vesicle;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0030139//endocytic vesicle;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding GO:0002683//negative regulation of immune system process;GO:0045066//regulatory T cell differentiation;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006915//apoptotic process;GO:0030888//regulation of B cell proliferation;GO:0033554//cellular response to stress;GO:0042098//T cell proliferation;GO:0002683//negative regulation of immune system process;GO:0045066//regulatory T cell differentiation;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006915//apoptotic process;GO:0030888//regulation of B cell proliferation;GO:0033554//cellular response to stress;GO:0042098//T cell proliferation "gi|148667743|gb|EDL00160.1|/5.97211e-133/cytotoxic T-lymphocyte-associated protein 4, partial [Mus musculus]" 100043232 2644 0.653333333 0.743333333 0.186190056 Up 0.147504607 3110099E03Rik RIKEN cDNA 3110099E03 gene - - - - gi|149022941|gb|EDL79835.1|/1.53945e-12/rCG26979 [Rattus norvegicus] 26570 9227 20.54 21.09 0.038122913 Up 0.147354169 Slc7a11 "solute carrier family 7 (cationic amino acid transporter, y+ system), member 11" "K13869|1|0.0|952|mmu:26570|solute carrier family 7 (L-type amino acid transporter), member 11" GO:0043232;GO:0031224//intrinsic component of membrane;GO:0005783//endoplasmic reticulum GO:0046943//carboxylic acid transmembrane transporter activity GO:0046942//carboxylic acid transport;GO:0042221//response to chemical;GO:0030168//platelet activation gi|6756011|ref|NP_036120.1|/0/cystine/glutamate transporter [Mus musculus] 12236 3669 0.556666667 0.473333333 -0.233957173 Down 0.147269548 Bub1b "BUB1B, mitotic checkpoint serine/threonine kinase" K06637|1|0.0|1915|mmu:12236|mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1] - - - - 100504687 1968 0.453333333 0.533333333 0.234465254 Up 0.147269548 2810029C07Rik RIKEN cDNA 2810029C07 gene - - - - - 66500 9020 1.563333333 1.44 -0.11855661 Down 0.147250743 Slc30a7 "solute carrier family 30 (zinc transporter), member 7" "K09428|1|2e-162|577|mmu:13709|E74-like factor 1/2/4;K14692|2|4e-154|550|mmu:66500|solute carrier family 30 (zinc transporter), member 5/7" GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0001816//cytokine production;GO:0050852//T cell receptor signaling pathway;GO:0000041//transition metal ion transport gi|6679627|ref|NP_031946.1|/1.99957e-161/ETS-related transcription factor Elf-1 isoform 1 [Mus musculus] 107373 3199 1.406666667 1.29 -0.124909433 Down 0.147250743 Fam111a "family with sequence similarity 111, member A" - - - - gi|13386132|ref|NP_080916.1|/0/protein FAM111A [Mus musculus] 26934 3071 1.476666667 1.356666667 -0.122277904 Down 0.147250743 Racgap1 Rac GTPase-activating protein 1 K16733|1|0.0|1216|mmu:26934|Rac GTPase-activating protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0032155;GO:0005819//spindle;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0032155;GO:0005819//spindle;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0032155;GO:0005819//spindle GO:0008047//enzyme activator activity;GO:0043169//cation binding;GO:0015631//tubulin binding;GO:0019900//kinase binding;GO:0008047//enzyme activator activity;GO:0043169//cation binding;GO:0015631//tubulin binding;GO:0019900//kinase binding;GO:0008047//enzyme activator activity;GO:0043169//cation binding;GO:0015631//tubulin binding;GO:0019900//kinase binding GO:0043087//regulation of GTPase activity;GO:0007275//multicellular organism development;GO:0032467//positive regulation of cytokinesis;GO:0015698//inorganic anion transport;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0000912//assembly of actomyosin apparatus involved in cytokinesis;GO:0007165//signal transduction;GO:0051255//spindle midzone assembly;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0000920//cell separation after cytokinesis;GO:0043087//regulation of GTPase activity;GO:0007275//multicellular organism development;GO:0032467//positive regulation of cytokinesis;GO:0015698//inorganic anion transport;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0000912//assembly of actomyosin apparatus involved in cytokinesis;GO:0007165//signal transduction;GO:0051255//spindle midzone assembly;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0000920//cell separation after cytokinesis;GO:0043087//regulation of GTPase activity;GO:0007275//multicellular organism development;GO:0032467//positive regulation of cytokinesis;GO:0015698//inorganic anion transport;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0000912//assembly of actomyosin apparatus involved in cytokinesis;GO:0007165//signal transduction;GO:0051255//spindle midzone assembly;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0000920//cell separation after cytokinesis "gi|148672172|gb|EDL04119.1|/0/Rac GTPase-activating protein 1, isoform CRA_a, partial [Mus musculus]" 73144 3023.57 1.33 1.446666667 0.121306296 Up 0.147250743 3110039I08Rik RIKEN cDNA 3110039I08 gene - - - - "gi|148693585|gb|EDL25532.1|/5.13542e-30/mCG5072, partial [Mus musculus]" 218989 5210 1.53 1.41 -0.11783649 Down 0.147250743 Tmem260 transmembrane protein 260 - GO:0031224//intrinsic component of membrane - - gi|26344293|dbj|BAC35803.1|/0/unnamed protein product [Mus musculus] 14702 3678 1.453333333 1.576666667 0.117512049 Up 0.147250743 Gng2 "guanine nucleotide binding protein (G protein), gamma 2" K07826|1|4e-34|150|myd:102771107|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 - - - - 70004 1215 0.213333333 0.153333333 -0.476438044 Down 0.147184926 1700028J19Rik RIKEN cDNA 1700028J19 gene - - - - "gi|148690758|gb|EDL22705.1|/7.54939e-82/mCG5707, isoform CRA_b [Mus musculus]" 71870 1822 0.216666667 0.156666667 -0.467778961 Down 0.147184926 Cfap45 cilia and flagella associated protein 45 K12484|1|1e-12|77.8|mze:101465789|Rab11 family-interacting protein 1/2/5;K18626|2|7e-11|71.6|ocu:100337740|trichohyalin - - - "gi|254675124|ref|NP_082248.1|/0/protein CFAP45, mitochondrial [Mus musculus]" 57258 3456 0.34 0.273333333 -0.314873337 Down 0.147137914 Xpo4 exportin 4 K18460|1|1e-20|105|der:Dere_GG19359|exportin-7 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0006611//protein export from nucleus gi|10048438|ref|NP_065252.1|/0/exportin-4 [Mus musculus] 330959 781 20.7 20.16 -0.038135129 Down 0.147109707 Snapc5 "small nuclear RNA activating complex, polypeptide 5" K15211|1|3e-27|124|mmu:330959|snRNA-activating protein complex subunit 5 GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated" "gi|148694110|gb|EDL26057.1|/2.3894e-30/small nuclear RNA activating complex, polypeptide 5, partial [Mus musculus]" 18571 5963.16 19.95333333 19.41333333 -0.039581923 Down 0.147109707 Pdcd6ip programmed cell death 6 interacting protein K12200|1|0.0|1366|mmu:18571|programmed cell death 6-interacting protein GO:0048770;GO:0015630//microtubule cytoskeleton;GO:0048770;GO:0015630//microtubule cytoskeleton;GO:0048770;GO:0015630//microtubule cytoskeleton GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding GO:0045184//establishment of protein localization;GO:0012501//programmed cell death;GO:0045184//establishment of protein localization;GO:0012501//programmed cell death;GO:0045184//establishment of protein localization;GO:0012501//programmed cell death "gi|148677001|gb|EDL08948.1|/0/programmed cell death 6 interacting protein, isoform CRA_a, partial [Mus musculus]" 216443 2966.99 18.54333333 19.08666667 0.041664565 Up 0.147109707 Mars methionine-tRNA synthetase K01874|1|0.0|1733|mmu:216443|methionyl-tRNA synthetase [EC:6.1.1.10] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0032550;GO:0003676//nucleic acid binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0004812//aminoacyl-tRNA ligase activity "GO:0006418//tRNA aminoacylation for protein translation;GO:0006351//transcription, DNA-templated;GO:0006418//tRNA aminoacylation for protein translation;GO:0006351//transcription, DNA-templated" "gi|284172357|ref|NP_001165053.1|/0/methionine--tRNA ligase, cytoplasmic isoform 1 [Mus musculus]" 226470 8362 0.996666667 0.893333333 -0.157912484 Down 0.147090902 Zbtb41 zinc finger and BTB domain containing 41 K10513|1|0.0|1741|mmu:226470|zinc finger and BTB domain-containing protein 41 - - - - 77036 745 0.946666667 0.846666667 -0.161062433 Down 0.147090902 1700109H08Rik RIKEN cDNA 1700109H08 gene K13338|1|1e-77|291|cfa:475227|peroxin-1;K06268|2|2e-15|84.7|myd:102760712|serine/threonine-protein phosphatase 2B regulatory subunit;K19932|4|9e-14|79.3|xla:399297|neuronal calcium sensor 1 - - - "gi|148682659|gb|EDL14606.1|/1.57088e-121/mCG6119, isoform CRA_b, partial [Mus musculus]" 100034739 3329 0.84 0.936666667 0.157146397 Up 0.147090902 Gm17762 "predicted gene, 17762" - - - - gi|820999209|ref|XP_012354755.1|/1.03206e-24/PREDICTED: protein CASC10 [Nomascus leucogenys] 383103 3321 0.893333333 0.996666667 0.157912484 Up 0.147090902 Tvp23a trans-golgi network vesicle protein 23A K03593|1|5e-16|65.9|nvi:100114376|ATP-binding protein involved in chromosome partitioning - - - - 22696 3495 0.833333333 0.933333333 0.163498732 Up 0.147090902 Zfp37 zinc finger protein 37 K09228|1|0.0|1174|mmu:22696|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0003006//developmental process involved in reproduction;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0003006//developmental process involved in reproduction;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0003006//developmental process involved in reproduction;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0003006//developmental process involved in reproduction" gi|594140613|ref|NP_001277280.1|/0/zinc finger protein 37 isoform 3 [Mus musculus] 16560 8243 0.23 0.166666667 -0.464668267 Down 0.147034488 Kif1a kinesin family member 1A K10392|1|0.0|3167|mmu:16560|kinesin family member 1 GO:0044297//cell body;GO:0042995//cell projection;GO:0015630//microtubule cytoskeleton;GO:0044297//cell body;GO:0042995//cell projection;GO:0015630//microtubule cytoskeleton;GO:0044297//cell body;GO:0042995//cell projection;GO:0015630//microtubule cytoskeleton;GO:0044297//cell body;GO:0042995//cell projection;GO:0015630//microtubule cytoskeleton GO:0008289//lipid binding;GO:0015631//tubulin binding;GO:0003774//motor activity;GO:0032550;GO:0008289//lipid binding;GO:0015631//tubulin binding;GO:0003774//motor activity;GO:0032550;GO:0008289//lipid binding;GO:0015631//tubulin binding;GO:0003774//motor activity;GO:0032550;GO:0008289//lipid binding;GO:0015631//tubulin binding;GO:0003774//motor activity;GO:0032550 GO:0006928//movement of cell or subcellular component;GO:0006928//movement of cell or subcellular component;GO:0006928//movement of cell or subcellular component;GO:0006928//movement of cell or subcellular component gi|160333877|ref|NP_001103785.1|/0/kinesin-like protein KIF1A isoform b [Mus musculus] 319371 2820 0.22 0.16 -0.459431619 Down 0.147034488 D030028A08Rik RIKEN cDNA D030028A08 gene - - - - "gi|148684109|gb|EDL16056.1|/4.75484e-84/mCG60780, isoform CRA_a, partial [Mus musculus]" 22670 3231 9.296666667 8.976666667 -0.050533705 Down 0.146996878 Trim26 tripartite motif-containing 26 K12008|1|0.0|935|mmu:22670|tripartite motif-containing protein 26 GO:0044424;GO:0044424;GO:0044424 GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - gi|128485541|ref|NP_001020770.2|/0/tripartite motif-containing protein 26 [Mus musculus] 67150 952 9.16 8.843333333 -0.050757329 Down 0.146996878 Rnf141 ring finger protein 141 K15692|1|2e-07|58.9|aec:105149567|E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27];K10667|3|2e-07|58.5|aam:106485567|E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27] - GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|74181715|dbj|BAE32570.1|/8.12096e-155/unnamed protein product [Mus musculus] 16164 3734 9.4 9.076666667 -0.05049818 Down 0.146996878 Il13ra1 "interleukin 13 receptor, alpha 1" K05076|1|0.0|859|mmu:16164|interleukin 13 receptor alpha-1 GO:0031224//intrinsic component of membrane GO:0004896//cytokine receptor activity GO:0030888//regulation of B cell proliferation gi|40254373|ref|NP_598751.3|/0/interleukin-13 receptor subunit alpha-1 precursor [Mus musculus] 234776 4900 9.386666667 9.07 -0.049510377 Down 0.146996878 Atmin ATM interactor - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0000975//regulatory region DNA binding;GO:0005515//protein binding "GO:0033554//cellular response to stress;GO:0006351//transcription, DNA-templated" gi|755526684|ref|XP_011246666.1|/0/PREDICTED: ATM interactor isoform X1 [Mus musculus] 56505 1670 9.316666667 8.993333333 -0.050957935 Down 0.146996878 Ruvbl1 RuvB-like protein 1 K04499|1|0.0|890|cge:100761458|RuvB-like protein 1 (pontin 52) - - - - 78910 4268 19.14 18.61 -0.040512774 Down 0.14688405 Asb15 ankyrin repeat and SOCS box-containing 15 K10337|1|0.0|1172|mmu:78910|ankyrin repeat and SOCS box protein 15 - - GO:0007165//signal transduction gi|755515544|ref|XP_011239390.1|/0/PREDICTED: ankyrin repeat and SOCS box protein 15 isoform X4 [Mus musculus] 66596 1315 18.57666667 19.10333333 0.040332743 Up 0.14688405 Gtf3a general transcription factor III A K09191|1|0.0|729|mmu:66596|general transcription factor IIIA - - - "gi|148673872|gb|EDL05819.1|/0/general transcription factor III A, isoform CRA_a, partial [Mus musculus]" 216151 3762 17.81 17.28 -0.043584299 Down 0.14688405 Polrmt polymerase (RNA) mitochondrial (DNA directed) "K10908|1|0.0|2251|mmu:216151|DNA-directed RNA polymerase, mitochondrial [EC:2.7.7.6]" GO:0005759//mitochondrial matrix GO:0034062//RNA polymerase activity GO:0000959//mitochondrial RNA metabolic process;GO:0010467//gene expression "gi|281332113|ref|NP_766139.2|/0/DNA-directed RNA polymerase, mitochondrial precursor [Mus musculus]" 21647 652 0.156666667 0.213333333 0.445411148 Up 0.146639588 Tcte3 t-complex-associated testis expressed 3 - - - - gi|51491908|ref|NP_932772.1|/2.14895e-75/tctex1 domain-containing protein 3 isoform 2 [Mus musculus] 70727 3185 0.213333333 0.156666667 -0.445411148 Down 0.146639588 Rasgef1a "RasGEF domain family, member 1A" K08020|1|2e-20|104|shr:100931445|Rap guanine nucleotide exchange factor 6;K08018|2|3e-20|103|cmk:103182258|Rap guanine nucleotide exchange factor 2 - - GO:0019222//regulation of metabolic process;GO:0048870//cell motility;GO:0019222//regulation of metabolic process;GO:0048870//cell motility gi|568942845|ref|XP_006506658.1|/0/PREDICTED: ras-GEF domain-containing family member 1A isoform X1 [Mus musculus] 57896 1819 18.93666667 18.42 -0.039909341 Down 0.14645154 Krcc1 lysine-rich coiled-coil 1 - - - - gi|21704142|ref|NP_663543.1|/1.23686e-132/lysine-rich coiled-coil protein 1 [Mus musculus] 20339 2912 0.24 0.176666667 -0.442004547 Down 0.146432735 Sele "selectin, endothelial cell" "K06494|1|0.0|1252|mmu:20339|selectin, endothelial cell" GO:0031224//intrinsic component of membrane;GO:0005856//cytoskeleton;GO:0012505//endomembrane system;GO:0044421;GO:0044459;GO:0044444//cytoplasmic part GO:0030246//carbohydrate binding;GO:0038023//signaling receptor activity;GO:0031406//carboxylic acid binding;GO:0019899//enzyme binding GO:0002090//regulation of receptor internalization;GO:0010863//positive regulation of phospholipase C activity;GO:0034097//response to cytokine;GO:0006954//inflammatory response;GO:0007159//leukocyte cell-cell adhesion;GO:0019932//second-messenger-mediated signaling;GO:0002237//response to molecule of bacterial origin;GO:0002684//positive regulation of immune system process gi|6755452|ref|NP_035475.1|/0/E-selectin precursor [Mus musculus] 12143 2475 0.166666667 0.226666667 0.443606651 Up 0.146432735 Blk B lymphoid kinase K08890|1|0.0|1016|mmu:12143|B lymphoid tyrosine kinase [EC:2.7.10.2] GO:0016020//membrane GO:0032550;GO:0004713//protein tyrosine kinase activity GO:0050796//regulation of insulin secretion;GO:0006464//cellular protein modification process;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006796//phosphate-containing compound metabolic process "gi|148704117|gb|EDL36064.1|/0/B lymphoid kinase, partial [Mus musculus]" 407814 2043 0.17 0.23 0.436099115 Up 0.146432735 BC053393 cDNA sequence BC053393 K20413|1|2e-30|137|mmu:171283|hepatitis A virus cellular receptor 1 - - - gi|254553405|ref|NP_001020606.2|/6.08992e-91/uncharacterized protein LOC407814 precursor [Mus musculus] 243923 6604 0.176666667 0.24 0.442004547 Up 0.146432735 Rgs9bp regulator of G-protein signalling 9 binding protein "K13355|1|1e-07|62.8|cge:100758176|nucleoside diphosphate-linked moiety X motif 19, mitochondrial [EC:3.6.1.-]" GO:0031224//intrinsic component of membrane - GO:0007165//signal transduction;GO:0007601//visual perception gi|109735053|gb|AAI18007.1|/2.5126e-89/Regulator of G-protein signalling 9 binding protein [Mus musculus] 67712 4162 3.66 3.85 0.073014797 Up 0.146413931 Slc25a37 "solute carrier family 25, member 37" "K15113|1|7e-177|624|mmu:67712|solute carrier family 25 (mitochondrial iron transporter), member 28/37" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0055080//cation homeostasis;GO:0006826//iron ion transport gi|564386902|ref|XP_006252328.1|/0/PREDICTED: mitoferrin-1 isoform X1 [Rattus norvegicus] 67795 1632 3.516666667 3.703333333 0.074615818 Up 0.146413931 Rnls "renalase, FAD-dependent amine oxidase" K18208|1|2e-124|448|mmu:67795|renalase [EC:1.6.3.5] - - - - 73242 1998.36 4.136666667 3.946666667 -0.067834035 Down 0.146413931 Atat1 alpha tubulin acetyltransferase 1 K19573|1|2e-161|572|cge:100764669|alpha-tubulin N-acetyltransferase 1 [EC:2.3.1.108] - GO:0034212//peptide N-acetyltransferase activity;GO:0034212//peptide N-acetyltransferase activity GO:0018393//internal peptidyl-lysine acetylation;GO:0018393//internal peptidyl-lysine acetylation gi|625206686|ref|XP_007644565.1|/2.91007e-157/PREDICTED: alpha-tubulin N-acetyltransferase 1 isoform X3 [Cricetulus griseus] 241638 4280.5 3.856666667 4.043333333 0.068190686 Up 0.146413931 Lzts3 "leucine zipper, putative tumor suppressor family member 3" - - - - gi|672046788|ref|XP_008760372.1|/0/PREDICTED: leucine zipper putative tumor suppressor 3 isoform X5 [Rattus norvegicus] 227867 4358 3.893333333 4.086666667 0.069918705 Up 0.146413931 Epc2 enhancer of polycomb homolog 2 (Drosophila) K11322|1|0.0|1316|mmu:227867|enhancer of polycomb-like protein GO:0035267//NuA4 histone acetyltransferase complex - "GO:0006259//DNA metabolic process;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" gi|26326949|dbj|BAC27218.1|/0/unnamed protein product [Mus musculus] 235406 4564 3.91 4.103333333 0.069627748 Up 0.146413931 Snx33 sorting nexin 33 K17923|1|0.0|1142|mmu:235406|sorting nexin-9/18/33 - GO:0005543//phospholipid binding GO:0044763 gi|66793416|ref|NP_780692.2|/0/sorting nexin-33 [Mus musculus] 434156 2424 3.743333333 3.93 0.070205791 Up 0.146413931 Eid2b EP300 interacting inhibitor of differentiation 2B - - - - gi|294459954|ref|NP_001170898.1|/1.01797e-63/EP300-interacting inhibitor of differentiation 2B [Mus musculus] 105787 4655 4.036666667 3.843333333 -0.070806352 Down 0.146413931 Prkaa1 "protein kinase, AMP-activated, alpha 1 catalytic subunit" "K07198|1|0.0|1031|mmu:105787|5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]" GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044444//cytoplasmic part GO:0004690//cyclic nucleotide-dependent protein kinase activity;GO:0032550;GO:0043169//cation binding;GO:0019899//enzyme binding "GO:0034614//cellular response to reactive oxygen species;GO:0006679//glucosylceramide biosynthetic process;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0022402//cell cycle process;GO:0006096//glycolytic process;GO:0032844//regulation of homeostatic process;GO:0006351//transcription, DNA-templated;GO:0045471//response to ethanol;GO:0009895;GO:0001666//response to hypoxia;GO:0033500//carbohydrate homeostasis;GO:0055081//anion homeostasis;GO:0006695//cholesterol biosynthetic process;GO:0019217//regulation of fatty acid metabolic process;GO:0009267//cellular response to starvation;GO:0009968//negative regulation of signal transduction;GO:0008283//cell proliferation;GO:0007623//circadian rhythm;GO:0046325//negative regulation of glucose import;GO:0009409//response to cold;GO:0016192//vesicle-mediated transport;GO:0051259//protein oligomerization;GO:0014074//response to purine-containing compound;GO:0006468//protein phosphorylation" gi|94681061|ref|NP_001013385.3|/0/5'-AMP-activated protein kinase catalytic subunit alpha-1 [Mus musculus] 66143 1039 9.066666667 9.373333333 0.047989943 Up 0.146376321 Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 K15439|1|6e-95|349|mmu:66143|eukaryotic translation elongation factor 1 epsilon-1 GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0005488//binding "GO:0006412//translation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006259//DNA metabolic process;GO:0006915//apoptotic process;GO:0007275//multicellular organism development;GO:0008283//cell proliferation" gi|13384756|ref|NP_079656.1|/5.09824e-94/eukaryotic translation elongation factor 1 epsilon-1 [Mus musculus] 53621 3476.54 9.473333333 9.786666667 0.046945414 Up 0.146376321 Cnot4 "CCR4-NOT transcription complex, subunit 4" K10643|1|0.0|1139|mmu:53621|CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity "GO:0016567//protein ubiquitination;GO:0006351//transcription, DNA-templated;GO:0016567//protein ubiquitination;GO:0006351//transcription, DNA-templated;GO:0016567//protein ubiquitination;GO:0006351//transcription, DNA-templated;GO:0016567//protein ubiquitination;GO:0006351//transcription, DNA-templated;GO:0016567//protein ubiquitination;GO:0006351//transcription, DNA-templated" gi|256985132|ref|NP_001157885.1|/0/CCR4-NOT transcription complex subunit 4 isoform 1 [Mus musculus] 57912 2925.24 8.676666667 8.986666667 0.050645185 Up 0.146376321 Cdc42se1 CDC42 small effector 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0004857//enzyme inhibitor activity;GO:0004857//enzyme inhibitor activity GO:0007254//JNK cascade;GO:0022604//regulation of cell morphogenesis;GO:0006897//endocytosis;GO:0007254//JNK cascade;GO:0022604//regulation of cell morphogenesis;GO:0006897//endocytosis gi|27369483|ref|NP_765983.1|/3.6301e-40/CDC42 small effector protein 1 [Mus musculus] 67765 1494 0.303333333 0.37 0.286621226 Up 0.1462917 5830432E09Rik RIKEN cDNA 5830432E09 gene K18033|1|2e-07|59.7|cge:100756593|receptor-type tyrosine-protein phosphatase epsilon [EC:3.1.3.48] - - - - 12727 4224.52 16.9 16.38666667 -0.044500832 Down 0.14625409 Clcn4 "chloride channel, voltage-sensitive 4" - GO:0031224//intrinsic component of membrane;GO:0005770//late endosome;GO:0005769//early endosome;GO:0031224//intrinsic component of membrane;GO:0005770//late endosome;GO:0005769//early endosome GO:0032550;GO:0015291//secondary active transmembrane transporter activity;GO:0005254//chloride channel activity;GO:0032550;GO:0015291//secondary active transmembrane transporter activity;GO:0005254//chloride channel activity GO:0044763;GO:0015698//inorganic anion transport;GO:0044763;GO:0015698//inorganic anion transport gi|880903389|ref|XP_012971887.1|/0/PREDICTED: H(+)/Cl(-) exchange transporter 4 isoform X1 [Mesocricetus auratus] 66368 1576 16.29666667 16.81 0.04474282 Up 0.14625409 Rtca RNA 3'-terminal phosphate cyclase K01974|1|0.0|753|cge:100760159|RNA 3'-terminal phosphate cyclase (ATP) [EC:6.5.1.4] GO:0043231//intracellular membrane-bounded organelle GO:0009975//cyclase activity;GO:0032550 GO:0010467//gene expression gi|625236815|ref|XP_007609607.1|/0/PREDICTED: LOW QUALITY PROTEIN: RNA 3'-terminal phosphate cyclase isoform X2 [Cricetulus griseus] 75060 975 16.37 16.88333333 0.044545446 Up 0.14625409 4930506C21Rik RIKEN cDNA 4930506C21 gene - - - - - 97884 3681 5.336666667 5.11 -0.062615611 Down 0.146207078 B3galnt2 "UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2" "K09654|1|0.0|962|mmu:97884|beta-1,3-N-acetylgalactosaminyltransferase 2 [EC:2.4.1.-]" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system "GO:0016758//transferase activity, transferring hexosyl groups" GO:0006464//cellular protein modification process "gi|47716521|ref|NP_848755.1|/0/UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 precursor [Mus musculus]" 16588 1379 5.763333333 5.99 0.05565254 Up 0.146207078 Kin Kin17 DNA and RNA binding protein K13102|1|0.0|646|mmu:16588|DNA/RNA-binding protein KIN17 - - - - 105835 3013 5.346666667 5.576666667 0.060763304 Up 0.146207078 Sgsm3 small G protein signaling modulator 3 K20176|1|0.0|1469|rno:362963|small G protein signaling modulator 3 GO:0005911//cell-cell junction;GO:0044424 GO:0017016//Ras GTPase binding GO:0022402//cell cycle process;GO:0032482//Rab protein signal transduction;GO:0009896 "gi|148672644|gb|EDL04591.1|/0/RUN and TBC1 domain containing 3, isoform CRA_b, partial [Mus musculus]" 17974 2789 5.166666667 5.396666667 0.06283477 Up 0.146207078 Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 K19862|1|0.0|733|mmu:17974|NCK adaptor protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0044444//cytoplasmic part "GO:0030674//protein binding, bridging;GO:0032947//protein complex scaffold" GO:0038127//ERBB signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0006412//translation;GO:0030041//actin filament polymerization;GO:0048870//cell motility;GO:0030031//cell projection assembly;GO:0010469//regulation of receptor activity;GO:0006935//chemotaxis;GO:0042098//T cell proliferation gi|190610036|ref|NP_035009.3|/0/cytoplasmic protein NCK2 [Mus musculus] 319565 21718 1.18 1.293333333 0.132307292 Up 0.146197676 Syne2 "spectrin repeat containing, nuclear envelope 2" K19346|1|0.0|1.271e+04|mmu:319565|nesprin-2 - - - gi|145699091|ref|NP_001005510.2|/0/nesprin-2 [Mus musculus] 233532 11129 1.16 1.266666667 0.126912112 Up 0.146197676 Rsf1 remodeling and spacing factor 1 K11657|1|0.0|2166|mmu:233532|remodeling and spacing factor 1 - - - gi|124486905|ref|NP_001074736.1|/0/remodeling and spacing factor 1 [Mus musculus] 22324 4096 1.293333333 1.18 -0.132307292 Down 0.146197676 Vav1 vav 1 oncogene K05730|1|0.0|1573|mmu:22324|guanine nucleotide exchange factor VAV GO:0044464;GO:0044464;GO:0044464 GO:0043169//cation binding;GO:0008289//lipid binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity GO:0007166//cell surface receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0007155//cell adhesion;GO:0006897//endocytosis;GO:0030098//lymphocyte differentiation;GO:0007166//cell surface receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0007155//cell adhesion;GO:0006897//endocytosis;GO:0030098//lymphocyte differentiation;GO:0007166//cell surface receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0007155//cell adhesion;GO:0006897//endocytosis;GO:0030098//lymphocyte differentiation gi|255308869|ref|NP_001157288.1|/0/proto-oncogene vav isoform 3 [Mus musculus] 13649 5604.2 1.33 1.216666667 -0.128492282 Down 0.146197676 Egfr epidermal growth factor receptor K04361|1|0.0|2282|mmu:13649|epidermal growth factor receptor [EC:2.7.10.1] "GO:0031224//intrinsic component of membrane;GO:0044459;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0030234//enzyme regulator activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0019902//phosphatase binding;GO:0032550;GO:0019838//growth factor binding;GO:0046983//protein dimerization activity;GO:0003779//actin binding;GO:0030234//enzyme regulator activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0019902//phosphatase binding;GO:0032550;GO:0019838//growth factor binding;GO:0046983//protein dimerization activity;GO:0003779//actin binding "GO:0006954//inflammatory response;GO:0010467//gene expression;GO:0001775//cell activation;GO:0006915//apoptotic process;GO:0001701//in utero embryonic development;GO:0019229//regulation of vasoconstriction;GO:0006281//DNA repair;GO:0043405//regulation of MAP kinase activity;GO:0008284//positive regulation of cell proliferation;GO:0006809//nitric oxide biosynthetic process;GO:0009612//response to mechanical stimulus;GO:0032989;GO:0007423//sensory organ development;GO:0010243//response to organonitrogen compound;GO:0031175//neuron projection development;GO:0035411//catenin import into nucleus;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0031657//regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0021987//cerebral cortex development;GO:0042311//vasodilation;GO:0055065//metal ion homeostasis;GO:0035249//synaptic transmission, glutamatergic;GO:0009895;GO:0002009//morphogenesis of an epithelium;GO:0016477//cell migration;GO:0009411//response to UV;GO:0008544//epidermis development;GO:0080184//response to phenylpropanoid;GO:0070848//response to growth factor;GO:0006790//sulfur compound metabolic process;GO:0005975//carbohydrate metabolic process;GO:0043627//response to estrogen;GO:0006260//DNA replication;GO:0071385//cellular response to glucocorticoid stimulus;GO:0048511//rhythmic process;GO:0044702//single organism reproductive process;GO:0010038//response to metal ion;GO:0006721//terpenoid metabolic process;GO:0007155//cell adhesion;GO:0032768;GO:0030323//respiratory tube development;GO:0038127//ERBB signaling pathway;GO:0042493//response to drug;GO:0007431//salivary gland development;GO:0006954//inflammatory response;GO:0010467//gene expression;GO:0001775//cell activation;GO:0006915//apoptotic process;GO:0001701//in utero embryonic development;GO:0019229//regulation of vasoconstriction;GO:0006281//DNA repair;GO:0043405//regulation of MAP kinase activity;GO:0008284//positive regulation of cell proliferation;GO:0006809//nitric oxide biosynthetic process;GO:0009612//response to mechanical stimulus;GO:0032989;GO:0007423//sensory organ development;GO:0010243//response to organonitrogen compound;GO:0031175//neuron projection development;GO:0035411//catenin import into nucleus;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0031657//regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0021987//cerebral cortex development;GO:0042311//vasodilation;GO:0055065//metal ion homeostasis;GO:0035249//synaptic transmission, glutamatergic;GO:0009895;GO:0002009//morphogenesis of an epithelium;GO:0016477//cell migration;GO:0009411//response to UV;GO:0008544//epidermis development;GO:0080184//response to phenylpropanoid;GO:0070848//response to growth factor;GO:0006790//sulfur compound metabolic process;GO:0005975//carbohydrate metabolic process;GO:0043627//response to estrogen;GO:0006260//DNA replication;GO:0071385//cellular response to glucocorticoid stimulus;GO:0048511//rhythmic process;GO:0044702//single organism reproductive process;GO:0010038//response to metal ion;GO:0006721//terpenoid metabolic process;GO:0007155//cell adhesion;GO:0032768;GO:0030323//respiratory tube development;GO:0038127//ERBB signaling pathway;GO:0042493//response to drug;GO:0007431//salivary gland development" gi|46560582|ref|NP_997538.1|/0/epidermal growth factor receptor isoform 1 precursor [Mus musculus] 108150 4363 1.123333333 1.23 0.130872225 Up 0.146197676 Galnt7 UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7 K00710|1|0.0|1226|rno:29750|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008376//acetylgalactosaminyltransferase activity;GO:0016740//transferase activity GO:0006486//protein glycosylation;GO:0006486//protein glycosylation gi|269784709|ref|NP_001161453.1|/0/N-acetylgalactosaminyltransferase 7 isoform 2 [Mus musculus] 228807 3247 2.65 2.81 0.084577771 Up 0.14609425 Zfp341 zinc finger protein 341 K09228|1|3e-62|243|bfo:BRAFLDRAFT_71028|KRAB domain-containing zinc finger protein - - - gi|76559897|ref|NP_955008.2|/0/zinc finger protein 341 [Mus musculus] 224109 3559 2.826666667 2.67 -0.082262022 Down 0.14609425 Nrros negative regulator of reactive oxygen species "K01384|1|7e-35|152|amj:102558673|wingless-type MMTV integration site family, member 11;K17256|3|4e-26|123|xma:102229118|insulin-like growth factor-binding protein complex acid labile subunit;K18808|4|1e-25|121|xma:102222731|toll-like receptor 13" GO:0031224//intrinsic component of membrane - - gi|31542583|ref|NP_666181.2|/0/negative regulator of reactive oxygen species [Mus musculus] 12752 2481.29 2.76 2.916666667 0.079652249 Up 0.14609425 Cln3 "ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)" K12389|1|0.0|728|mmu:12752|battenin - - - gi|226423881|ref|NP_034037.3|/0/battenin [Mus musculus] 72667 4331 2.956666667 2.796666667 -0.080263294 Down 0.14609425 Zfp444 zinc finger protein 444 K09230|1|1e-177|626|mmu:72667|SCAN domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated;GO:0044764;GO:0006351//transcription, DNA-templated;GO:0044764" "gi|148699362|gb|EDL31309.1|/5.20523e-178/zinc finger protein 444, isoform CRA_b, partial [Mus musculus]" 100503068 2461 0.173333333 0.233333333 0.428843299 Up 0.146084847 Gm11549 predicted gene 11549 - - - - gi|532055492|ref|XP_005370459.1|/1.97472e-22/PREDICTED: uncharacterized protein LOC101994174 [Microtus ochrogaster] 192188 8152 0.246666667 0.183333333 -0.428093652 Down 0.146084847 Stab2 stabilin 2 K19013|1|0.0|5258|mmu:192188|stabilin-2 GO:0016021//integral component of membrane;GO:0044424 GO:0071813//lipoprotein particle binding;GO:0038024//cargo receptor activity;GO:0005539//glycosaminoglycan binding GO:0006952//defense response;GO:0016192//vesicle-mediated transport;GO:0022610 gi|20149764|ref|NP_619614.1|/0/stabilin-2 precursor [Mus musculus] 414095 1406 0.176666667 0.236666667 0.421826665 Up 0.146084847 B130034C11Rik RIKEN cDNA B130034C11 gene - - - - - 266645 2303 0.253333333 0.19 -0.415037499 Down 0.146084847 Acmsd amino carboxymuconate semialdehyde decarboxylase K03392|1|0.0|703|mmu:266645|aminocarboxymuconate-semialdehyde decarboxylase [EC:4.1.1.45] GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0016831//carboxy-lyase activity GO:0006586;GO:0009820//alkaloid metabolic process;GO:0043648//dicarboxylic acid metabolic process gi|74315894|ref|NP_001028213.1|/0/2-amino-3-carboxymuconate-6-semialdehyde decarboxylase [Mus musculus] 30943 1469 0.17 0.226666667 0.415037499 Up 0.146084847 Prss30 "protease, serine 30" K09639|1|1e-166|588|mmu:30943|transmembrane protease serine 8 [EC:3.4.21.-] GO:0031225//anchored component of membrane GO:0004175//endopeptidase activity;GO:0016247//channel regulator activity GO:0019538//protein metabolic process;GO:0030001//metal ion transport gi|24496768|ref|NP_038949.2|/1.09e-165/serine protease 30 precursor [Mus musculus] 380934 1984 0.25 0.186666667 -0.421463768 Down 0.146084847 AA536875 expressed sequence AA536875 - - - - gi|537176156|gb|ERE75043.1|/5.84375e-08/proton-coupled amino acid transporter 4 [Cricetulus griseus] 52023 3297 1.006666667 0.91 -0.145647598 Down 0.145925007 Pibf1 progesterone immunomodulatory binding factor 1 K16538|1|0.0|1391|mmu:52023|progesterone-induced-blocking factor 1 - - - gi|46852193|ref|NP_083596.2|/0/progesterone-induced-blocking factor 1 [Mus musculus] 224008 3303 0.87 0.966666667 0.152003093 Up 0.145925007 Spidr scaffolding protein involved in DNA repair "K10436|1|9e-98|361|tru:101069236|microtubule-associated protein, RP/EB family" - - - gi|31541868|ref|NP_666180.2|/0/DNA repair-scaffolding protein [Mus musculus] 241525 752 0.953333333 1.056666667 0.148467693 Up 0.145925007 Ypel4 yippee-like 4 (Drosophila) K04371|1|6e-08|60.1|asn:102375250|mitogen-activated protein kinase 1/3 [EC:2.7.11.24] GO:0031981//nuclear lumen - - gi|537146482|gb|ERE69964.1|/2.94203e-91/protein yippee-like 4-like protein [Cricetulus griseus] 239546 2233 0.883333333 0.98 0.149823795 Up 0.145925007 Zfp647 zinc finger protein 647 K09228|1|0.0|1110|mmu:239546|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|269954713|ref|NP_766405.2|/0/zinc finger protein 250 [Mus musculus] 66329 1144 0.96 1.063333333 0.147487612 Up 0.145925007 Susd3 sushi domain containing 3 K17495|1|3e-06|55.5|bfo:BRAFLDRAFT_92287|CUB and sushi domain-containing protein GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|21702740|ref|NP_079767.2|/9.69075e-121/sushi domain-containing protein 3 isoform 1 [Mus musculus] 75029 1607.08 0.946666667 1.05 0.149460899 Up 0.145925007 Purg purine-rich element binding protein G K11838|1|8e-42|174|chx:102188997|ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding - gi|585652696|ref|XP_006884183.1|/0/PREDICTED: purine-rich element-binding protein gamma-like isoform X1 [Elephantulus edwardii] 216148 3974 1.003333333 0.903333333 -0.151470635 Down 0.145925007 Shc2 SHC (Src homology 2 domain containing) transforming protein 2 K17447|1|0.0|1078|mmu:216148|SHC-transforming protein 2 GO:0044444//cytoplasmic part - GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007264//small GTPase mediated signal transduction gi|169790806|ref|NP_001019710.1|/0/SHC-transforming protein 2 [Mus musculus] 13641 3375 19.46 18.96333333 -0.03729913 Down 0.145896799 Efnb1 ephrin B1 K05463|1|3e-164|582|mmu:13641|ephrin-B GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005102//receptor binding GO:0048869//cellular developmental process;GO:0048731//system development;GO:0001667//ameboidal-type cell migration;GO:0006935//chemotaxis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0042098//T cell proliferation;GO:0009790//embryo development gi|6753726|ref|NP_034240.1|/2.17165e-163/ephrin-B1 precursor [Mus musculus] 16169 1694.86 16.20333333 16.70666667 0.044133281 Up 0.145896799 Il15ra "interleukin 15 receptor, alpha chain" K05074|1|4e-32|141|mmu:16169|interleukin 15 receptor alpha GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0001779//natural killer cell differentiation;GO:0010975//regulation of neuron projection development;GO:0001779//natural killer cell differentiation;GO:0010975//regulation of neuron projection development;GO:0001779//natural killer cell differentiation;GO:0010975//regulation of neuron projection development;GO:0001779//natural killer cell differentiation;GO:0010975//regulation of neuron projection development;GO:0001779//natural killer cell differentiation;GO:0010975//regulation of neuron projection development;GO:0001779//natural killer cell differentiation;GO:0010975//regulation of neuron projection development;GO:0001779//natural killer cell differentiation;GO:0010975//regulation of neuron projection development;GO:0001779//natural killer cell differentiation;GO:0010975//regulation of neuron projection development;GO:0001779//natural killer cell differentiation;GO:0010975//regulation of neuron projection development "gi|148676077|gb|EDL08024.1|/4.20728e-101/interleukin 15 receptor, alpha chain, isoform CRA_e, partial [Mus musculus]" 14367 6823 0.78 0.686666667 -0.183864192 Down 0.145718154 Fzd5 frizzled class receptor 5 K02375|1|0.0|1058|ngi:103744444|frizzled 5/8 - - - - 67307 2211 0.68 0.77 0.179323699 Up 0.145718154 Pbld2 phenazine biosynthesis-like protein domain containing 2 - - GO:0003824//catalytic activity GO:0008152//metabolic process gi|568968265|ref|XP_006514046.1|/4.39184e-167/PREDICTED: phenazine biosynthesis-like domain-containing protein 2 isoform X3 [Mus musculus] 74451 2298 9.373333333 9.676666667 0.045947978 Up 0.145671142 Pgs1 phosphatidylglycerophosphate synthase 1 K00995|1|0.0|932|mmu:74451|CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5] GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0032550;GO:0017169//CDP-alcohol phosphatidyltransferase activity;GO:0046872//metal ion binding GO:0006655//phosphatidylglycerol biosynthetic process;GO:0006639//acylglycerol metabolic process "gi|148702702|gb|EDL34649.1|/0/mCG19305, isoform CRA_c, partial [Mus musculus]" 66932 5249 8.613333333 8.316666667 -0.050566254 Down 0.145671142 Rexo1 "REX1, RNA exonuclease 1" K14570|1|0.0|2038|mmu:66932|RNA exonuclease 1 [EC:3.1.-.-] GO:0043231//intracellular membrane-bounded organelle GO:0097159//organic cyclic compound binding;GO:0004518//nuclease activity - "gi|148699588|gb|EDL31535.1|/0/REX1, RNA exonuclease 1 homolog (S. cerevisiae), isoform CRA_c, partial [Mus musculus]" 386655 1299 8.693333333 8.99 0.048411652 Up 0.145671142 Eid2 EP300 interacting inhibitor of differentiation 2 - GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding "GO:0048869//cellular developmental process;GO:0048513//animal organ development;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation" gi|38259218|ref|NP_940817.1|/3.58984e-53/EP300-interacting inhibitor of differentiation 2 [Mus musculus] 11834 4897 8.323333333 8.02 -0.053559179 Down 0.145671142 Aqr aquarius K12874|1|0.0|2767|mmu:11834|intron-binding protein aquarius GO:0005681//spliceosomal complex;GO:0005681//spliceosomal complex GO:0036002//pre-mRNA binding;GO:0036002//pre-mRNA binding GO:0006396//RNA processing;GO:0006396//RNA processing gi|595763222|ref|NP_001277717.1|/0/intron-binding protein aquarius isoform b [Mus musculus] 64295 1343 9.073333333 8.773333333 -0.048507578 Down 0.145671142 Tmub1 transmembrane and ubiquitin-like domain containing 1 K08290|1|1e-09|67.0|gfr:102034598|Fas-activated serine/threonine kinase [EC:2.7.11.8] GO:0005634//nucleus - - gi|568933337|ref|XP_006535848.1|/8.88733e-95/PREDICTED: transmembrane and ubiquitin-like domain-containing protein 1 isoform X2 [Mus musculus] 320554 3512 0.403333333 0.333333333 -0.275007047 Down 0.145642935 Tcp11l1 t-complex 11 like 1 - GO:0015630//microtubule cytoskeleton - - gi|28893201|ref|NP_796164.1|/0/T-complex protein 11-like protein 1 [Mus musculus] 27660 1183.24 19.49666667 19.00333333 -0.036974988 Down 0.145595923 1700088E04Rik RIKEN cDNA 1700088E04 gene - - - - gi|887517009|ref|NP_001297505.1|/1.59708e-105/UPF0193 protein EVG1 homolog isoform 2 [Mus musculus] 72017 1626 17.12666667 16.64 -0.041588956 Down 0.145595923 Cyb5r1 cytochrome b5 reductase 1 K00326|1|1e-161|572|mmu:72017|cytochrome-b5 reductase [EC:1.6.2.2] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0016653//oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor" GO:0006694//steroid biosynthetic process gi|21312524|ref|NP_082333.1|/1.20945e-160/NADH-cytochrome b5 reductase 1 [Mus musculus] 75087 944 0.06 0.113333333 0.91753784 Up 0.14546429 4930505A04Rik RIKEN cDNA 4930505A04 gene - - - - gi|154240699|ref|NP_001093864.1|/1.74831e-135/uncharacterized protein C2orf73 homolog [Mus musculus] 81799 2350 0.11 0.06 -0.874469118 Down 0.14546429 C1qtnf3 C1q and tumor necrosis factor related protein 3 K18744|1|5e-22|109|acs:100567071|caprin-2 GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix GO:0005515//protein binding;GO:0005515//protein binding GO:0055082//cellular chemical homeostasis;GO:0006094//gluconeogenesis;GO:0050663//cytokine secretion;GO:0032675//regulation of interleukin-6 production;GO:0010467//gene expression;GO:0033500//carbohydrate homeostasis;GO:0046887//positive regulation of hormone secretion;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0051259//protein oligomerization;GO:0006954//inflammatory response;GO:0043410//positive regulation of MAPK cascade;GO:0032682//negative regulation of chemokine production;GO:0055082//cellular chemical homeostasis;GO:0006094//gluconeogenesis;GO:0050663//cytokine secretion;GO:0032675//regulation of interleukin-6 production;GO:0010467//gene expression;GO:0033500//carbohydrate homeostasis;GO:0046887//positive regulation of hormone secretion;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0051259//protein oligomerization;GO:0030154//cell differentiation;GO:0006954//inflammatory response;GO:0043410//positive regulation of MAPK cascade;GO:0032682//negative regulation of chemokine production gi|625202502|ref|XP_003504210.2|/1.27443e-114/PREDICTED: complement C1q tumor necrosis factor-related protein 3 isoform X2 [Cricetulus griseus] 16643 866 0.063333333 0.116666667 0.881355504 Up 0.14546429 Klrd1 "killer cell lectin-like receptor, subfamily D, member 1" K06516|1|1e-103|378|mmu:16643|killer cell lectin-like receptor subfamily D member 1 - - - - 104522 1038 0.096666667 0.05 -0.9510904 Down 0.14546429 AU040972 expressed sequence AU040972 - - - - - 14167 3239.78 0.056666667 0.11 0.956931278 Up 0.14546429 Fgf12 fibroblast growth factor 12 K04358|1|1e-48|197|shr:100931315|fibroblast growth factor GO:0043231//intracellular membrane-bounded organelle;GO:0044421;GO:0043231//intracellular membrane-bounded organelle;GO:0044421;GO:0043231//intracellular membrane-bounded organelle;GO:0044421 GO:0070851//growth factor receptor binding;GO:0005539//glycosaminoglycan binding;GO:0070851//growth factor receptor binding;GO:0005539//glycosaminoglycan binding;GO:0070851//growth factor receptor binding;GO:0005539//glycosaminoglycan binding GO:0048731//system development;GO:0051403//stress-activated MAPK cascade;GO:0007267//cell-cell signaling;GO:0002028//regulation of sodium ion transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007626//locomotory behavior;GO:0044767//single-organism developmental process;GO:0032413//negative regulation of ion transmembrane transporter activity;GO:0050877//neurological system process;GO:0048731//system development;GO:0051403//stress-activated MAPK cascade;GO:0007267//cell-cell signaling;GO:0002028//regulation of sodium ion transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007626//locomotory behavior;GO:0044767//single-organism developmental process;GO:0032413//negative regulation of ion transmembrane transporter activity;GO:0050877//neurological system process;GO:0048731//system development;GO:0051403//stress-activated MAPK cascade;GO:0007267//cell-cell signaling;GO:0002028//regulation of sodium ion transport;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007626//locomotory behavior;GO:0044767//single-organism developmental process;GO:0032413//negative regulation of ion transmembrane transporter activity;GO:0050877//neurological system process gi|11136630|ref|NP_066360.1|/3.86997e-132/fibroblast growth factor 12 isoform 1 [Homo sapiens] 102641247 936 0.06 0.11 0.874469118 Up 0.14546429 Gm12339 predicted gene 12339 K19917|1|6e-08|60.5|lve:103088625|double C2-like domain-containing protein beta - - - - 76560 1874 0.056666667 0.103333333 0.866733469 Up 0.14546429 Prss8 "protease, serine 8 (prostasin)" K08664|1|0.0|654|mmu:76560|prostasin [EC:3.4.21.-];K09630|3|2e-171|604|cge:100758312|polyserase 2 [EC:3.4.21.-] GO:0019898//extrinsic component of membrane;GO:0031225//anchored component of membrane;GO:0044421 GO:0004175//endopeptidase activity;GO:0016247//channel regulator activity GO:0002028//regulation of sodium ion transport;GO:0019538//protein metabolic process;GO:0031960//response to corticosteroid "gi|148685661|gb|EDL17608.1|/0/protease, serine, 8 (prostasin), isoform CRA_b, partial [Mus musculus]" 71398 3835 0.053333333 0.103333333 0.95419631 Up 0.14546429 5430427O19Rik RIKEN cDNA 5430427O19 gene - - - - gi|254692863|ref|NP_001157011.1|/3.27832e-155/uncharacterized protein CXorf21 homolog [Mus musculus] 100038371 934 0.113333333 0.06 -0.91753784 Down 0.14546429 Zfp389 zinc finger protein 389 K09229|1|5e-83|310|cfr:102515564|KRAB and SCAN domains-containing zinc finger protein - - - - 27390 2948 0.103333333 0.053333333 -0.95419631 Down 0.14546429 Mmel1 membrane metallo-endopeptidase-like 1 K08635|1|0.0|1523|mmu:27390|membrane metallo-endopeptidase-like 1 - - - - 76132 9342 0.053333333 0.1 0.906890596 Up 0.14546429 Faxc failed axon connections homolog K17776|1|7e-13|80.9|dre:286741|metaxin - - - - 613264 1047 0.1 0.053333333 -0.906890596 Down 0.14546429 1810020O05Rik Riken cDNA 1810020O05 gene - - - - - 20147 5855 0.1 0.053333333 -0.906890596 Down 0.14546429 Rs1 "retinoschisis (X-linked, juvenile) 1 (human)" K16669|1|2e-27|128|sko:100371900|protocadherin Fat 4;K03902|2|7e-27|126|pss:102446403|coagulation factor V (labile factor) GO:0019898//extrinsic component of membrane;GO:0044421 GO:1901981//phosphatidylinositol phosphate binding;GO:0043168//anion binding GO:0016056//rhodopsin mediated signaling pathway;GO:0022610;GO:0003407//neural retina development;GO:0050953//sensory perception of light stimulus gi|42476341|ref|NP_035432.3|/2.04788e-127/retinoschisin precursor [Mus musculus] 104932 987 0.106666667 0.056666667 -0.912537159 Down 0.14546429 AU015791 expressed sequence AU015791 - - - - - 73321 1091 0.096666667 0.05 -0.9510904 Down 0.14546429 1700042O10Rik RIKEN cDNA 1700042O10 gene - - - - - 15001 1064 0.1 0.053333333 -0.906890596 Down 0.14546429 H2-Oa "histocompatibility 2, O region alpha locus" "K06752|1|2e-127|457|mmu:15001|major histocompatibility complex, class II" GO:0031224//intrinsic component of membrane;GO:0042611 - GO:0002478;GO:0030217//T cell differentiation "gi|226054226|ref|NP_032232.2|/1.79964e-126/histocompatibility 2, O region alpha locus precursor [Mus musculus]" 242864 3673 1.81 1.943333333 0.102543685 Up 0.145454887 Napepld N-acyl phosphatidylethanolamine phospholipase D K13985|1|0.0|794|mmu:242864|N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D [EC:3.1.4.54] - GO:0046914//transition metal ion binding;GO:0004620//phospholipase activity GO:0006644//phospholipid metabolic process gi|568933182|ref|XP_006535772.1|/0/PREDICTED: N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D isoform X2 [Mus musculus] 76850 6527 1.92 1.786666667 -0.103835811 Down 0.145454887 Ago4 argonaute RISC catalytic subunit 4 K11593|1|0.0|1731|mmu:76850|eukaryotic translation initiation factor 2C GO:0035770//ribonucleoprotein granule;GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding GO:0006412//translation;GO:0006401//RNA catabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0035195//gene silencing by miRNA gi|26325989|dbj|BAC26738.1|/0/unnamed protein product [Mus musculus] 70381 4195 17.35666667 16.87333333 -0.040744899 Down 0.145379668 Tecpr1 tectonin beta-propeller repeat containing 1 K17988|1|0.0|2362|mmu:70381|tectonin beta-propeller repeat-containing protein 1 GO:0031982//vesicle;GO:0005764//lysosome;GO:0005774//vacuolar membrane;GO:0031224//intrinsic component of membrane GO:1901981//phosphatidylinositol phosphate binding GO:0016236//macroautophagy "gi|148687074|gb|EDL19021.1|/0/mCG122828, isoform CRA_b, partial [Mus musculus]" 213081 4403 0.363333333 0.436666667 0.265238677 Up 0.145201023 Wdr19 WD repeat domain 19 K19671|1|0.0|2667|mmu:213081|WD repeat-containing protein 19 GO:0030990//intraciliary transport particle;GO:0043232;GO:0031513//nonmotile primary cilium - GO:0048704//embryonic skeletal system morphogenesis;GO:0007224//smoothened signaling pathway;GO:0043010//camera-type eye development;GO:0048858//cell projection morphogenesis;GO:0010927;GO:0003008;GO:0043583//ear development;GO:0035108//limb morphogenesis gi|154240688|ref|NP_700440.2|/0/WD repeat-containing protein 19 [Mus musculus] 71132 1599.5 0.43 0.356666667 -0.269760269 Down 0.145201023 Cabyr calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2) - GO:0044441;GO:0043232;GO:0044441;GO:0031981//nuclear lumen;GO:0043232;GO:0044441;GO:0031981//nuclear lumen;GO:0043232;GO:0044441;GO:0031981//nuclear lumen;GO:0043232;GO:0044441;GO:0043232 GO:0019900//kinase binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0019887//protein kinase regulator activity;GO:0019900//kinase binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0019887//protein kinase regulator activity;GO:0019900//kinase binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0019900//kinase binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0019887//protein kinase regulator activity;GO:0019900//kinase binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0019887//protein kinase regulator activity GO:0019932//second-messenger-mediated signaling;GO:0006461//protein complex assembly;GO:0003006//developmental process involved in reproduction;GO:0019932//second-messenger-mediated signaling;GO:0006461//protein complex assembly;GO:0003006//developmental process involved in reproduction;GO:0019932//second-messenger-mediated signaling;GO:0006461//protein complex assembly;GO:0003006//developmental process involved in reproduction;GO:0019932//second-messenger-mediated signaling;GO:0006461//protein complex assembly;GO:0003006//developmental process involved in reproduction;GO:0019932//second-messenger-mediated signaling;GO:0006461//protein complex assembly;GO:0003006//developmental process involved in reproduction gi|109255222|ref|NP_001035884.1|/3.49248e-83/calcium-binding tyrosine phosphorylation-regulated protein isoform e [Mus musculus] 71774 3312 0.33 0.396666667 0.265461143 Up 0.145201023 Shroom1 shroom family member 1 K18625|1|0.0|1430|mmu:71774|protein Shroom GO:0016459//myosin complex;GO:0016459//myosin complex;GO:0015630//microtubule cytoskeleton GO:0003779//actin binding;GO:0003779//actin binding GO:0007015//actin filament organization;GO:0007015//actin filament organization gi|125628648|ref|NP_082193.2|/0/protein Shroom1 isoform 1 [Mus musculus] 11946 2443 2075.89 2125.833333 0.034298495 Up 0.145135206 Atp5a1 "ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1" K02132|1|0.0|1024|mmu:11946|F-type H+-transporting ATPase subunit alpha "GO:0033178//proton-transporting two-sector ATPase complex, catalytic domain;GO:0005753//mitochondrial proton-transporting ATP synthase complex" GO:0042287//MHC protein binding;GO:0032550;GO:0019829//cation-transporting ATPase activity "GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0007275//multicellular organism development;GO:0001935//endothelial cell proliferation;GO:0006754//ATP biosynthetic process;GO:0009154//purine ribonucleotide catabolic process" "gi|589921997|ref|XP_006973917.1|/0/PREDICTED: ATP synthase subunit alpha, mitochondrial [Peromyscus maniculatus bairdii]" 16832 1336.2 1552.436667 1589.353333 0.033905476 Up 0.145116402 Ldhb lactate dehydrogenase B K00016|1|0.0|660|mmu:16832|L-lactate dehydrogenase [EC:1.1.1.27] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0004457//lactate dehydrogenase activity;GO:0019899//enzyme binding;GO:0000166//nucleotide binding;GO:0004457//lactate dehydrogenase activity;GO:0019899//enzyme binding;GO:0000166//nucleotide binding;GO:0004457//lactate dehydrogenase activity;GO:0019899//enzyme binding;GO:0000166//nucleotide binding GO:0006007//glucose catabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0046496//nicotinamide nucleotide metabolic process;GO:0006007//glucose catabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0046496//nicotinamide nucleotide metabolic process;GO:0006007//glucose catabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0046496//nicotinamide nucleotide metabolic process gi|938085832|ref|NP_001303251.1|/3.08634e-158/L-lactate dehydrogenase B chain isoform Ldhbx [Mus musculus] 13628 2111 1182.64 1211.33 0.03458097 Up 0.145097597 Eef1a2 eukaryotic translation elongation factor 1 alpha 2 K03231|1|0.0|912|rno:24799|elongation factor 1-alpha GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043234//protein complex "GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008135//translation factor activity, RNA binding" GO:0042221//response to chemical;GO:0006412//translation;GO:0006915//apoptotic process;GO:0009154//purine ribonucleotide catabolic process gi|913508551|ref|XP_013207515.1|/0/PREDICTED: elongation factor 1-alpha 2 [Microtus ochrogaster] 11949 1183.55 1045.536667 1069.796667 0.033092956 Up 0.14506939 Atp5c1 "ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1" K02136|1|9e-162|572|mmu:11949|F-type H+-transporting ATPase subunit gamma - - - - 228033 730.75 1068.67 1043.56 -0.034302873 Down 0.14506939 Atp5g3 "ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)" K02128|1|2e-58|228|mmu:228033|F-type H+-transporting ATPase subunit c "GO:0031224//intrinsic component of membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0005740//mitochondrial envelope" GO:0005488//binding;GO:0015077//monovalent inorganic cation transmembrane transporter activity "GO:0097305//response to alcohol;GO:0044767//single-organism developmental process;GO:0006754//ATP biosynthetic process;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient" gi|537152032|gb|ERE71959.1|/1.83881e-58/ATP synthase lipid-binding protein [Cricetulus griseus] 56012 906 970.4566667 993.34 0.033623813 Up 0.14506939 Pgam2 phosphoglycerate mutase 2 "K01834|1|2e-146|520|mmu:56012|2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]" GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0004619//phosphoglycerate mutase activity;GO:0034416//bisphosphoglycerate phosphatase activity GO:0006007//glucose catabolic process;GO:0010038//response to metal ion;GO:0048232//male gamete generation;GO:0006936//muscle contraction gi|9256624|ref|NP_061358.1|/1.32792e-145/phosphoglycerate mutase 2 [Mus musculus] 13531 2661 0.376666667 0.45 0.256636635 Up 0.144965963 Usp17la ubiquitin specific peptidase 17-like A K11845|1|0.0|1028|mmu:13531|ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12] - GO:0019783//ubiquitin-like protein-specific protease activity GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process gi|6681237|ref|NP_031913.1|/0/ubiquitin carboxyl-terminal hydrolase 17-like protein A [Mus musculus] 70454 2327 0.35 0.42 0.263034406 Up 0.144965963 Cenpl centromere protein L K11504|1|2e-176|524|mmu:70454|centromere protein L - - - - 73598 957 0.426666667 0.356666667 -0.258533014 Down 0.144965963 1700001O22Rik RIKEN cDNA 1700001O22 gene - - - - gi|258679514|ref|NP_932117.2|/0/uncharacterized protein C9orf50 homolog [Mus musculus] 219228 9509 0.4 0.333333333 -0.263034406 Down 0.144965963 Pcdh17 protocadherin 17 K16499|1|0.0|2170|mmu:219228|protocadherin delta 2 - - - gi|554556611|ref|XP_005872735.1|/0/PREDICTED: protocadherin-17 isoform X3 [Myotis brandtii] 29811 2145.76 800.5533333 817.9233333 0.030968102 Up 0.144965963 Ndrg2 N-myc downstream regulated gene 2 K18266|1|4e-95|351|cmy:102943732|protein NDRG1 GO:0005815//microtubule organizing center;GO:0043005//neuron projection;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0005815//microtubule organizing center;GO:0043005//neuron projection;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part - GO:0048869//cellular developmental process;GO:0048731//system development;GO:0043409//negative regulation of MAPK cascade;GO:0008285//negative regulation of cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0001817//regulation of cytokine production;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0043409//negative regulation of MAPK cascade;GO:0008285//negative regulation of cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0001817//regulation of cytokine production gi|225543196|ref|NP_001139431.1|/0/protein NDRG2 isoform 2 [Mus musculus] 12419 8814.37 5.293333333 5.51 0.057875812 Up 0.144947159 Cbx5 chromobox 5 K11587|1|2e-104|364|ngi:103738875|chromobox protein 5 "GO:0016604//nuclear body;GO:0000775//chromosome, centromeric region;GO:0005720//nuclear heterochromatin;GO:0034708;GO:0012505//endomembrane system;GO:0016604//nuclear body;GO:0000775//chromosome, centromeric region;GO:0005720//nuclear heterochromatin;GO:0034708;GO:0012505//endomembrane system;GO:0016604//nuclear body;GO:0000790//nuclear chromatin;GO:0034708;GO:0000775//chromosome, centromeric region" GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0019899//enzyme binding;GO:0008134//transcription factor binding;GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0019899//enzyme binding;GO:0008134//transcription factor binding;GO:0042393//histone binding;GO:0042802//identical protein binding;GO:0019899//enzyme binding;GO:0008134//transcription factor binding "GO:0006351//transcription, DNA-templated;GO:0007599//hemostasis;GO:0006351//transcription, DNA-templated;GO:0007599//hemostasis;GO:0006351//transcription, DNA-templated" gi|880869781|ref|XP_012966716.1|/9.58061e-105/PREDICTED: chromobox protein homolog 5 isoform X1 [Mesocricetus auratus] 72775 1926.82 5.67 5.893333333 0.055735134 Up 0.144947159 Fance "Fanconi anemia, complementation group E" K10892|1|0.0|479|mmu:72775|fanconi anemia group E protein - - - gi|255652993|ref|NP_001157291.1|/0/Fanconi anemia group E protein isoform 1 [Mus musculus] 232784 2719.04 5.616666667 5.836666667 0.055430492 Up 0.144947159 Zfp212 Zinc finger protein 212 K09228|1|0.0|922|mmu:232784|KRAB domain-containing zinc finger protein - GO:0005515//protein binding;GO:0043169//cation binding;GO:0005515//protein binding;GO:0043169//cation binding - gi|37360616|dbj|BAC98286.1|/0/mKIAA3011 protein [Mus musculus] 319740 5520.21 5.43 5.213333333 -0.058746091 Down 0.144947159 Zfyve27 "zinc finger, FYVE domain containing 27" K19368|1|0.0|820|mmu:319740|protrudin - GO:0043169//cation binding;GO:0043169//cation binding - gi|256985190|ref|NP_796293.2|/0/protrudin isoform 1 [Mus musculus] 225372 2077 5.923333333 5.7 -0.055447356 Down 0.144947159 Apbb3 "amyloid beta (A4) precursor protein-binding, family B, member 3" K04530|1|1e-101|373|gja:107111015|amyloid beta A4 precursor protein-binding family B member 2 GO:0005856//cytoskeleton GO:0005488//binding GO:0006915//apoptotic process gi|22122589|ref|NP_666197.1|/0/amyloid beta A4 precursor protein-binding family B member 3 [Mus musculus] 17268 3434.28 5.233333333 5.45 0.058526077 Up 0.144947159 Meis1 Meis homeobox 1 K15613|1|0.0|892|cge:100751815|homeobox protein Meis1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0046983//protein dimerization activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0046983//protein dimerization activity" GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030099//myeloid cell differentiation;GO:0001568//blood vessel development;GO:0002088//lens development in camera-type eye;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030099//myeloid cell differentiation;GO:0001568//blood vessel development;GO:0002088//lens development in camera-type eye;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter "gi|148675868|gb|EDL07815.1|/0/myeloid ecotropic viral integration site 1, isoform CRA_a, partial [Mus musculus]" 619289 2024 0.12 0.066666667 -0.847996907 Down 0.144909549 Rfx8 regulatory factor X 8 K19521|1|3e-46|189|spu:585554|regulatory factor X 6;K09174|3|3e-45|186|hmg:100205362|regulatory factor X 4 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|224586779|ref|NP_001139132.1|/0/DNA-binding protein RFX8 [Mus musculus] 18707 4782.79 2.1 2.236666667 0.090960938 Up 0.144900147 Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide "K00922|1|0.0|1922|mmu:18707|phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]" - - - "gi|255708437|ref|NP_001025008.2|/0/phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform b [Mus musculus]" 75901 5616 2.243333333 2.38 0.085317569 Up 0.144900147 Dcp1a decapping mRNA 1A K12610|1|0.0|1107|mmu:75901|mRNA-decapping enzyme 1A [EC:3.-.-.-] - - - - 56217 5529 2.31 2.17 -0.090197809 Down 0.144900147 Mpp5 "membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)" K06091|1|0.0|1264|mmu:56217|MAGUK p55 subfamily member 5 GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0043218//compact myelin;GO:0044424 GO:0005515//protein binding GO:0090150//establishment of protein localization to membrane;GO:0008105//asymmetric protein localization;GO:0010927;GO:0009117//nucleotide metabolic process;GO:0022011//myelination in peripheral nervous system gi|9625023|ref|NP_062525.1|/0/MAGUK p55 subfamily member 5 [Mus musculus] 109785 4582 2.08 2.22 0.093976148 Up 0.144900147 Pgm3 phosphoglucomutase 3 K01836|1|0.0|976|mmu:109785|phosphoacetylglucosamine mutase [EC:5.4.2.3] - "GO:0043169//cation binding;GO:0016868//intramolecular transferase activity, phosphotransferases" GO:0048534//hematopoietic or lymphoid organ development;GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0048232//male gamete generation gi|255522941|ref|NP_001157218.1|/0/phosphoacetylglucosamine mutase isoform 2 [Mus musculus] 270118 5017.05 2.06 2.196666667 0.092671627 Up 0.144900147 Maml2 mastermind like 2 (Drosophila) K06061|1|0.0|910|mmu:270118|mastermind - - - gi|37360560|dbj|BAC98258.1|/0/mKIAA1819 protein [Mus musculus] 75605 6300 2.176666667 2.313333333 0.087852671 Up 0.144900147 Kdm5b lysine (K)-specific demethylase 5B K11446|1|0.0|2910|mmu:75605|histone demethylase JARID1 [EC:1.14.11.-] GO:0031981//nuclear lumen "GO:0003712//transcription cofactor activity;GO:0032453//histone demethylase activity (H3-K4 specific);GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0001071//nucleic acid binding transcription factor activity" "GO:0034720//histone H3-K4 demethylation;GO:0006351//transcription, DNA-templated" "gi|148707655|gb|EDL39602.1|/0/jumonji, AT rich interactive domain 1B (Rbp2 like), isoform CRA_a, partial [Mus musculus]" 19691 3367.84 2.456666667 2.313333333 -0.086728957 Down 0.144900147 Recql RecQ protein-like K10899|1|0.0|1210|mmu:19691|ATP-dependent DNA helicase Q1 [EC:3.6.4.12] GO:0005856//cytoskeleton;GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0031981//nuclear lumen GO:0032550;GO:0003676//nucleic acid binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0004003//ATP-dependent DNA helicase activity GO:0032392//DNA geometric change;GO:0032392//DNA geometric change;GO:0032392//DNA geometric change gi|110625690|ref|NP_075529.2|/0/ATP-dependent DNA helicase Q1 isoform 1 [Mus musculus] 75965 5173 2.206666667 2.343333333 0.086693472 Up 0.144900147 Zdhhc20 "zinc finger, DHHC domain containing 20" K20028|1|0.0|733|mmu:75965|palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225] GO:0031224//intrinsic component of membrane GO:0016740//transferase activity;GO:0046914//transition metal ion binding - gi|568989006|ref|XP_006519720.1|/0/PREDICTED: probable palmitoyltransferase ZDHHC20 isoform X1 [Mus musculus] 20639 1230 8.423333333 8.713333333 0.048833477 Up 0.144843732 Snrpb2 U2 small nuclear ribonucleoprotein B K11094|1|3e-109|397|mmu:20639|U2 small nuclear ribonucleoprotein B'' GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex;GO:0031981//nuclear lumen GO:0036094//small molecule binding;GO:0003723//RNA binding GO:0000377 gi|23956110|ref|NP_067310.1|/2.11962e-108/U2 small nuclear ribonucleoprotein B'' [Mus musculus] 223921 1816 8.373333333 8.086666667 -0.050256914 Down 0.144843732 Aaas "achalasia, adrenocortical insufficiency, alacrimia" K14320|1|0.0|1124|mmu:223921|aladin GO:0005635//nuclear envelope - GO:0051169//nuclear transport;GO:0019953//sexual reproduction;GO:0007611//learning or memory gi|241982696|ref|NP_700465.2|/0/aladin [Mus musculus] 207352 4578 7.49 7.776666667 0.054186183 Up 0.144843732 Sec23ip Sec23 interacting protein K16545|1|0.0|758|lcm:102359704|phospholipase DDHD2 [EC:3.1.1.-] GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding - gi|254692911|ref|NP_001025153.2|/0/SEC23-interacting protein [Mus musculus] 30840 1750 8.443333333 8.73 0.048168983 Up 0.144843732 Fbxl6 F-box and leucine-rich repeat protein 6 K10272|1|0.0|984|mmu:30840|F-box and leucine-rich repeat protein 6 - - GO:0032446//protein modification by small protein conjugation gi|274326390|ref|NP_038937.2|/0/F-box/LRR-repeat protein 6 [Mus musculus] 15516 2507 807.9166667 822.55 0.025896886 Up 0.14483433 Hsp90ab1 "heat shock protein 90 alpha (cytosolic), class B member 1" K04079|1|0.0|1214|pale:102887985|molecular chaperone HtpG GO:0005903//brush border;GO:0043234//protein complex;GO:0044459;GO:0048770 GO:0030234//enzyme regulator activity;GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0032551;GO:0032550;GO:0019904//protein domain specific binding;GO:0032558//adenyl deoxyribonucleotide binding "GO:0031330;GO:0070670//response to interleukin-4;GO:0006809//nitric oxide biosynthetic process;GO:0014070//response to organic cyclic compound;GO:0006970//response to osmotic stress;GO:0000060//protein import into nucleus, translocation;GO:0043393//regulation of protein binding;GO:0008361//regulation of cell size;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0035966//response to topologically incorrect protein;GO:0043066//negative regulation of apoptotic process;GO:0044767//single-organism developmental process;GO:0045860//positive regulation of protein kinase activity" gi|586556217|ref|XP_006926551.1|/0/PREDICTED: heat shock protein HSP 90-beta [Pteropus alecto] 71793 3099 3.63 3.45 -0.073373186 Down 0.144806123 Ints12 integrator complex subunit 12 K13149|1|7e-153|544|mmu:71793|integrator complex subunit 12 GO:0005634//nucleus - - gi|21313674|ref|NP_082203.1|/5.92677e-152/integrator complex subunit 12 [Mus musculus] 56194 3565 3.926666667 3.746666667 -0.067697504 Down 0.144806123 Prpf40a pre-mRNA processing factor 40A K12821|1|0.0|1286|mmu:56194|pre-mRNA-processing factor 40 - - - - 380601 3127 3.81 3.993333333 0.067802505 Up 0.144806123 Fastkd5 FAST kinase domains 5 K08290|1|4e-10|70.1|acs:103282002|Fas-activated serine/threonine kinase [EC:2.7.11.8] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016301//kinase activity;GO:0016301//kinase activity GO:0006464//cellular protein modification process;GO:0015980//energy derivation by oxidation of organic compounds;GO:0006464//cellular protein modification process;GO:0015980//energy derivation by oxidation of organic compounds gi|225703039|ref|NP_937819.2|/0/FAST kinase domain-containing protein 5 [Mus musculus] 208092 1561 16.95333333 17.41333333 0.038623435 Up 0.144759111 Chmp6 charged multivesicular body protein 6 K12195|1|5e-70|267|mmu:208092|charged multivesicular body protein 6 GO:0005768//endosome;GO:0016020//membrane GO:0005515//protein binding GO:0044765//single-organism transport;GO:0044763 gi|147904547|ref|NP_001078967.1|/4.60647e-69/charged multivesicular body protein 6 [Mus musculus] 76130 2623 16.51666667 16.97333333 0.039347362 Up 0.144759111 Las1l LAS1-like (S. cerevisiae) K16912|1|0.0|1238|mmu:76130|ribosomal biogenesis protein LAS1 GO:0044665//MLL1/2 complex - GO:0042254//ribosome biogenesis gi|71979675|ref|NP_690035.2|/0/ribosomal biogenesis protein LAS1L [Mus musculus] 53608 4333 17.31 17.76666667 0.037567308 Up 0.144759111 Map3k6 mitogen-activated protein kinase kinase kinase 6 K04425|1|0.0|2371|mmu:53608|mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25] - - - - 20469 3655.67 15.25333333 15.71 0.042558629 Up 0.144759111 Sipa1 signal-induced proliferation associated gene 1 K08013|1|0.0|1822|mmu:20469|signal-induced proliferation-associated gene 1 "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0032991//macromolecular complex;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0032991//macromolecular complex;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0032991//macromolecular complex;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0032991//macromolecular complex;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0032991//macromolecular complex" GO:0008047//enzyme activator activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0005515//protein binding GO:0009414//response to water deprivation;GO:0007049//cell cycle;GO:0007264//small GTPase mediated signal transduction;GO:0009414//response to water deprivation;GO:0007049//cell cycle;GO:0007264//small GTPase mediated signal transduction;GO:0009414//response to water deprivation;GO:0007049//cell cycle;GO:0007264//small GTPase mediated signal transduction;GO:0009414//response to water deprivation;GO:0007049//cell cycle;GO:0007264//small GTPase mediated signal transduction;GO:0009414//response to water deprivation;GO:0007049//cell cycle;GO:0007264//small GTPase mediated signal transduction gi|60360124|dbj|BAD90281.1|/0/mKIAA4074 protein [Mus musculus] 56356 1622 16.95333333 17.41333333 0.038623435 Up 0.144759111 Gltp glycolipid transfer protein K08051|1|6e-30|134|hmg:100201998|pleckstrin homology domain containing family A member 8 GO:0044424 GO:0005319//lipid transporter activity;GO:0008289//lipid binding GO:0006869//lipid transport gi|31560404|ref|NP_062795.2|/1.82372e-116/glycolipid transfer protein [Mus musculus] 232414 3132.65 1.57 1.45 -0.114711659 Down 0.144683892 Clec9a "C-type lectin domain family 9, member a" K17515|1|4e-54|216|mmu:232414|C-type lectin domain family 9 member A GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464 GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0050663//cytokine secretion;GO:0006897//endocytosis;GO:0050663//cytokine secretion;GO:0006897//endocytosis;GO:0050663//cytokine secretion;GO:0006897//endocytosis;GO:0050663//cytokine secretion;GO:0006897//endocytosis gi|26331362|dbj|BAC29411.1|/1.03839e-166/unnamed protein product [Mus musculus] 218850 7460.89 1.603333333 1.486666667 -0.108993184 Down 0.144683892 Fam208a "family with sequence similarity 208, member A" - - - - gi|168823452|ref|NP_001108351.1|/0/protein TASOR isoform 1 [Mus musculus] 101604 2163 1.61 1.733333333 0.106488434 Up 0.144683892 E430018J23Rik RIKEN cDNA E430018J23 gene K09228|1|0.0|984|mmu:101604|KRAB domain-containing zinc finger protein - - - gi|268370222|ref|NP_932128.2|/0/uncharacterized protein LOC101604 [Mus musculus] 240067 3008 1.463333333 1.58 0.110666119 Up 0.144683892 Zfp952 zinc finger protein 952 K09228|1|0.0|1082|mmu:240067|KRAB domain-containing zinc finger protein - - - "gi|148708328|gb|EDL40275.1|/0/cDNA sequence BC057593, partial [Mus musculus]" 60613 2512 1.573333333 1.453333333 -0.114458725 Down 0.144683892 Kcnq4 "potassium voltage-gated channel, subfamily Q, member 4" K04929|1|0.0|1151|mmu:60613|potassium voltage-gated channel KQT-like subfamily member 4 - - - "gi|148698471|gb|EDL30418.1|/0/mCG13518, partial [Mus musculus]" 66945 2859 491.5733333 480.3 -0.033470847 Down 0.144646282 Sdha "succinate dehydrogenase complex, subunit A, flavoprotein (Fp)" K00234|1|0.0|1284|mmu:66945|succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1] GO:0005746//mitochondrial respiratory chain GO:0000166//nucleotide binding;GO:0000104//succinate dehydrogenase activity GO:0048731//system development;GO:0022900//electron transport chain;GO:0043648//dicarboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0051234//establishment of localization "gi|54607098|ref|NP_075770.1|/0/succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial precursor [Mus musculus]" 232035 5628.41 0.25 0.19 -0.395928676 Down 0.144618075 Ccser1 coiled-coil serine rich 1 - - - - gi|256222323|ref|NP_899133.2|/0/serine-rich coiled-coil domain-containing protein 1 [Mus musculus] 408068 4523 0.193333333 0.256666667 0.408805546 Up 0.144618075 Zfp738 zinc finger protein 738 K09228|1|0.0|1452|mmu:212281|KRAB domain-containing zinc finger protein - - - gi|261245035|ref|NP_001001187.2|/0/zinc finger protein 738 [Mus musculus] 20346 6422 0.176666667 0.233333333 0.401362562 Up 0.144618075 Sema3a "sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A" K06840|1|0.0|1622|mmu:20346|semaphorin 3 GO:0043005//neuron projection;GO:0044421;GO:0043005//neuron projection;GO:0044421;GO:0043005//neuron projection;GO:0044421 - GO:0016358//dendrite development;GO:0060445//branching involved in salivary gland morphogenesis;GO:0010631//epithelial cell migration;GO:0008016//regulation of heart contraction;GO:0012501//programmed cell death;GO:0006935//chemotaxis;GO:0030517//negative regulation of axon extension;GO:0021988//olfactory lobe development;GO:0016358//dendrite development;GO:0060445//branching involved in salivary gland morphogenesis;GO:0010631//epithelial cell migration;GO:0008016//regulation of heart contraction;GO:0012501//programmed cell death;GO:0006935//chemotaxis;GO:0030517//negative regulation of axon extension;GO:0021988//olfactory lobe development;GO:0016358//dendrite development;GO:0060445//branching involved in salivary gland morphogenesis;GO:0010631//epithelial cell migration;GO:0008016//regulation of heart contraction;GO:0012501//programmed cell death;GO:0006935//chemotaxis;GO:0030517//negative regulation of axon extension;GO:0021988//olfactory lobe development gi|31543681|ref|NP_033178.2|/0/semaphorin-3A precursor [Mus musculus] 403174 2793 0.233333333 0.176666667 -0.401362562 Down 0.144618075 Msantd1 Myb/SANT-like DNA-binding domain containing 1 K04533|1|5e-39|166|mgp:100540532|huntingtin - - - gi|887222677|ref|NP_001297479.1|/5.97466e-99/myb/SANT-like DNA-binding domain-containing protein 1 isoform 2 [Mus musculus] 171469 2267 0.196666667 0.26 0.40275917 Up 0.144618075 Gpr37l1 G protein-coupled receptor 37-like 1 K04244|1|0.0|896|mmu:171469|endothelin type b receptor-like protein 2 GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|162417988|ref|NP_602320.2|/0/prosaposin receptor GPR37L1 precursor [Mus musculus] 14289 1296 0.196666667 0.26 0.40275917 Up 0.144618075 Fpr2 formyl peptide receptor 2 K04173|1|0.0|636|mmu:14289|formyl peptide receptor-like GO:0031224//intrinsic component of membrane GO:0008528//G-protein coupled peptide receptor activity GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway;GO:0022610;GO:0042221//response to chemical;GO:0006801//superoxide metabolic process gi|6679853|ref|NP_032065.1|/2.92828e-180/formyl peptide receptor 2 [Mus musculus] 17101 11806 0.246666667 0.186666667 -0.402098444 Down 0.144618075 Lyst lysosomal trafficking regulator K18953|1|3e-69|268|bfo:BRAFLDRAFT_100614|factor associated with neutral sphingomyelinase activation GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part GO:0005488//binding GO:0006952//defense response;GO:0002444;GO:0009306//protein secretion;GO:0001562//response to protozoan;GO:0001909//leukocyte mediated cytotoxicity;GO:0030101//natural killer cell activation;GO:0050900//leukocyte migration;GO:0042221//response to chemical;GO:0048753//pigment granule organization;GO:0002449;GO:0006796//phosphate-containing compound metabolic process;GO:0007599//hemostasis;GO:0007033//vacuole organization;GO:0055088//lipid homeostasis;GO:0033363//secretory granule organization;GO:0032509//endosome transport via multivesicular body sorting pathway gi|111955376|ref|NP_034878.2|/0/lysosomal-trafficking regulator [Mus musculus] 11304 7268 0.263333333 0.2 -0.396890153 Down 0.144618075 Abca4 "ATP-binding cassette, sub-family A (ABC1), member 4" "K05644|1|0.0|4566|mmu:11304|ATP-binding cassette, subfamily A (ABC1), member 4" GO:0016021//integral component of membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0005548//phospholipid transporter activity;GO:0015405 GO:0007602//phototransduction;GO:0015914//phospholipid transport;GO:0007601//visual perception;GO:0009154//purine ribonucleotide catabolic process gi|6671495|ref|NP_031404.1|/0/retinal-specific ATP-binding cassette transporter [Mus musculus] 224171 3974 0.256666667 0.193333333 -0.408805546 Down 0.144618075 C330027C09Rik RIKEN cDNA C330027C09 gene K20283|1|2e-09|68.2|gfr:102031748|golgin subfamily A member 4;K16770|4|5e-08|63.5|ngi:103734492|centriolin;K17975|5|6e-08|63.2|myb:102242327|kinectin GO:0044424;GO:0031224//intrinsic component of membrane - - "gi|148665688|gb|EDK98104.1|/0/RIKEN cDNA C330027C09, isoform CRA_a, partial [Mus musculus]" 233115 7671 0.246666667 0.186666667 -0.402098444 Down 0.144618075 Dpy19l3 dpy-19-like 3 (C. elegans) K04712|1|4e-07|61.6|ngi:103726289|sphingolipid Delta-4 desaturase [EC:1.14.-.-];K04257|2|2e-06|59.3|ngi:103735069|olfactory receptor GO:0031224//intrinsic component of membrane - - gi|33331375|gb|AAQ10888.1|/0/transmembrane protein [Mus musculus] 100503120 778 0.256666667 0.193333333 -0.408805546 Down 0.144618075 A930006K02Rik RIKEN cDNA A930006K02 gene - - - - gi|148671881|gb|EDL03828.1|/6.60702e-33/mCG147079 [Mus musculus] 244579 3212 0.783333333 0.696666667 -0.169157814 Down 0.144589868 Tox3 TOX high mobility group box family member 3 K18808|1|9e-31|138|bfo:BRAFLDRAFT_68489|toll-like receptor 13 - GO:0044212//transcription regulatory region DNA binding;GO:0042802//identical protein binding "GO:0019932//second-messenger-mediated signaling;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process" gi|170932534|ref|NP_766501.2|/4.8764e-165/TOX high mobility group box family member 3 [Mus musculus] 114604 6346 0.76 0.673333333 -0.174678531 Down 0.144589868 Prdm15 PR domain containing 15 K09228|1|8e-77|292|ptr:742564|KRAB domain-containing zinc finger protein - - - gi|226531251|ref|NP_659038.2|/0/PR domain zinc finger protein 15 [Mus musculus] 72171 3261 0.833333333 0.74 -0.171368418 Down 0.144589868 Shq1 SHQ1 homolog (S. cerevisiae) K14764|1|0.0|963|mmu:72171|protein SHQ1 GO:0016604//nuclear body - GO:0006915//apoptotic process;GO:0006364//rRNA processing "gi|148666958|gb|EDK99374.1|/0/SHQ1 homolog (S. cerevisiae), isoform CRA_b, partial [Mus musculus]" 237940 2553 0.706666667 0.793333333 0.166897309 Up 0.144589868 Aoc2 "amine oxidase, copper containing 2 (retina-specific)" K00276|1|0.0|1444|mmu:237940|primary-amine oxidase [EC:1.4.3.21] - "GO:0046914//transition metal ion binding;GO:0048037//cofactor binding;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor" GO:1901564;GO:0009712//catechol-containing compound metabolic process gi|34098972|ref|NP_849263.1|/0/retina-specific copper amine oxidase [Mus musculus] 77097 11864 0.793333333 0.706666667 -0.166897309 Down 0.144589868 Tanc2 "tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2" K10380|1|4e-43|181|myb:102251961|ankyrin;K15502|3|2e-42|179|spu:755512|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A - - GO:0043009//chordate embryonic development gi|124378026|ref|NP_851416.2|/0/protein TANC2 [Mus musculus] 26879 2283 0.71 0.8 0.172180975 Up 0.144589868 B3galnt1 "UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1" K00719|1|0.0|653|mmu:26879|galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase [EC:2.4.1.79] GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008376//acetylgalactosaminyltransferase activity;GO:0035250//UDP-galactosyltransferase activity GO:0006464//cellular protein modification process;GO:0009311//oligosaccharide metabolic process "gi|9910138|ref|NP_064410.1|/0/UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 [Mus musculus]" 14562 2109 0.183333333 0.24 0.388565288 Up 0.144552258 Gdf3 growth differentiation factor 3 K05495|1|0.0|706|mmu:14562|growth differentiation factor 1/3 GO:0044421 GO:0005102//receptor binding GO:0043009//chordate embryonic development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0040014//regulation of multicellular organism growth;GO:0000578//embryonic axis specification;GO:0007423//sensory organ development;GO:0009888//tissue development;GO:0048568//embryonic organ development;GO:0007154//cell communication gi|75677587|ref|NP_032134.2|/0/growth/differentiation factor 3 precursor [Mus musculus] 11363 1948 461.04 470.8233333 0.030293895 Up 0.144495844 Acadl "acyl-Coenzyme A dehydrogenase, long-chain" K00255|1|0.0|830|mmu:11363|long-chain-acyl-CoA dehydrogenase [EC:1.3.8.8] GO:0005740//mitochondrial envelope GO:0000166//nucleotide binding;GO:0003997//acyl-CoA oxidase activity;GO:0003995//acyl-CoA dehydrogenase activity GO:0006635//fatty acid beta-oxidation;GO:0001676//long-chain fatty acid metabolic process;GO:0009437//carnitine metabolic process;GO:0019218//regulation of steroid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006579//amino-acid betaine catabolic process;GO:0051260//protein homooligomerization;GO:0048871//multicellular organismal homeostasis "gi|31982520|ref|NP_031407.2|/0/long-chain specific acyl-CoA dehydrogenase, mitochondrial precursor [Mus musculus] " 14357 3715 0.603333333 0.52 -0.214443668 Down 0.144477039 Dtx1 "deltex 1, E3 ubiquitin ligase" K06058|1|0.0|1070|rno:687424|deltex [EC:2.3.2.27] - - - - 18751 8830 0.523333333 0.603333333 0.205225138 Up 0.144477039 Prkcb "protein kinase C, beta" K19662|1|0.0|1372|mmu:18751|classical protein kinase C beta type [EC:2.7.11.13] GO:0005903//brush border;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0035258//steroid hormone receptor binding;GO:0035184//histone threonine kinase activity;GO:0003713//transcription coactivator activity;GO:0032550;GO:0019901//protein kinase binding;GO:0046914//transition metal ion binding;GO:0016247//channel regulator activity GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0070838//divalent metal ion transport;GO:0009967//positive regulation of signal transduction;GO:0040007//growth;GO:0035405;GO:0010827//regulation of glucose transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0050853//B cell receptor signaling pathway;GO:0046649//lymphocyte activation;GO:0006875//cellular metal ion homeostasis;GO:0012501//programmed cell death;GO:0009743//response to carbohydrate;GO:0008286//insulin receptor signaling pathway gi|6679345|ref|NP_032881.1|/0/protein kinase C beta type isoform 1 [Mus musculus] 330350 2631 0.57 0.493333333 -0.208399149 Down 0.144477039 9130221F21Rik RIKEN cDNA 9130221F21 gene - - - - "gi|148704753|gb|EDL36700.1|/4.05134e-13/mCG146313, partial [Mus musculus]" 66934 2283 0.52 0.6 0.206450877 Up 0.144477039 Dsn1 "DSN1 homolog, MIS12 kinetochore complex component" K11544|1|0.0|655|mmu:66934|kinetochore-associated protein DSN1 - - - - 327958 6634 0.566666667 0.49 -0.209718591 Down 0.144477039 Pitpnm3 PITPNM family member 3 K00469|1|1e-14|86.3|pss:102444630|inositol oxygenase [EC:1.13.99.1];K13619|2|2e-08|65.5|ame:724115|phospholipase DDHD1 [EC:3.1.1.-];K16545|3|2e-08|65.5|mdo:100032958|phospholipase DDHD2 [EC:3.1.1.-] GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464 GO:0005548//phospholipid transporter activity;GO:0046872//metal ion binding;GO:0005102//receptor binding;GO:0005548//phospholipid transporter activity;GO:0046872//metal ion binding;GO:0005102//receptor binding GO:0051234//establishment of localization;GO:0006650//glycerophospholipid metabolic process;GO:0051234//establishment of localization;GO:0006650//glycerophospholipid metabolic process gi|126032319|ref|NP_001075110.1|/0/membrane-associated phosphatidylinositol transfer protein 3 isoform 2 [Mus musculus] 232217 2601 0.06 0.106666667 0.830074999 Up 0.144448832 4933427D06Rik RIKEN cDNA 4933427D06 gene - - - - - 258917 945 0.06 0.106666667 0.830074999 Up 0.144448832 Olfr1336 olfactory receptor 1336 K04257|1|1e-158|561|mmu:258917|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|22129061|ref|NP_667126.1|/9.58182e-158/olfactory receptor 1336 [Mus musculus] 23928 5930 0.123333333 0.07 -0.817135943 Down 0.144448832 Lamc3 laminin gamma 3 "K06247|1|0.0|3086|mmu:23928|laminin, gamma 3" GO:0005578//proteinaceous extracellular matrix - GO:0021782//glial cell development;GO:0050953//sensory perception of light stimulus;GO:0022610;GO:0043010//camera-type eye development gi|66392579|ref|NP_035966.2|/0/laminin subunit gamma-3 precursor [Mus musculus] 74959 887 0.066666667 0.116666667 0.807354922 Up 0.144448832 Platr14 pluripotency associated transcript 14 - - - - "gi|148695774|gb|EDL27721.1|/3.93008e-26/mCG145450, partial [Mus musculus]" 26424 3635 0.066666667 0.116666667 0.807354922 Up 0.144448832 Nr5a2 "nuclear receptor subfamily 5, group A, member 2" K08027|1|0.0|1060|mmu:26424|nuclear receptor subfamily 5 group A member 2 GO:0031981//nuclear lumen "GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0008289//lipid binding;GO:0000975//regulatory region DNA binding;GO:0043566//structure-specific DNA binding" GO:0008202//steroid metabolic process;GO:0007275//multicellular organism development;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0019079//viral genome replication;GO:0008283//cell proliferation;GO:0055092//sterol homeostasis gi|14010847|ref|NP_109601.1|/0/nuclear receptor subfamily 5 group A member 2 isoform 1 [Mus musculus] 332397 3945 0.123333333 0.07 -0.817135943 Down 0.144448832 Nanos1 nanos homolog 1 (Drosophila) K18741|1|2e-92|343|rno:365494|protein nanos 1 GO:0044444//cytoplasmic part GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0045182//translation regulator activity GO:0006412//translation;GO:0001667//ameboidal-type cell migration gi|564299465|ref|XP_006223852.1|/1.54286e-91/PREDICTED: nanos homolog 1 isoform X1 [Rattus norvegicus] 208154 3232.04 0.116666667 0.066666667 -0.807354922 Down 0.144448832 Btla B and T lymphocyte associated K06707|1|9e-161|570|mmu:208154|B- and T-lymphocyte attenuator GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0009986//cell surface GO:0005488//binding;GO:0005488//binding GO:0042130//negative regulation of T cell proliferation;GO:0030888//regulation of B cell proliferation;GO:0007165//signal transduction;GO:0042130//negative regulation of T cell proliferation;GO:0030888//regulation of B cell proliferation;GO:0007165//signal transduction gi|83700227|ref|NP_001032808.2|/6.64815e-162/B- and T-lymphocyte attenuator isoform 1 precursor [Mus musculus] 16834 3060 15.49666667 15.95 0.041598499 Up 0.144392418 Cog1 component of oligomeric golgi complex 1 K20288|1|0.0|1811|mmu:16834|conserved oligomeric Golgi complex subunit 1 GO:0043234//protein complex - GO:0045184//establishment of protein localization gi|159110754|ref|NP_038609.3|/0/conserved oligomeric Golgi complex subunit 1 [Mus musculus] 74764 2322 17.33 17.78 0.03698367 Up 0.144392418 Klc4 kinesin light chain 4 K10407|1|0.0|1060|mmu:74764|kinesin light chain GO:0005875//microtubule associated complex GO:0003774//motor activity - gi|13386370|ref|NP_083367.1|/0/kinesin light chain 4 [Mus musculus] 211446 4597 17.07333333 17.52333333 0.037532482 Up 0.144392418 Exoc3 exocyst complex component 3 K06110|1|0.0|1450|mmu:211446|exocyst complex component 3 - GO:0005488//binding GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport gi|47847438|dbj|BAD21391.1|/0/mFLJ00157 protein [Mus musculus] 67726 2590 14.87333333 15.32 0.042688284 Up 0.144392418 Fam114a2 "family with sequence similarity 114, member A2" - - - - gi|568975399|ref|XP_006534078.1|/0/PREDICTED: protein FAM114A2 isoform X5 [Mus musculus] 66447 635 325.3233333 332.75 0.032564365 Up 0.144307796 Mgst3 microsomal glutathione S-transferase 3 K00799|1|8e-87|321|mmu:66447|glutathione S-transferase [EC:2.5.1.18] - - - gi|13385010|ref|NP_079845.1|/5.58148e-86/microsomal glutathione S-transferase 3 [Mus musculus] 66416 541.44 311.4466667 319.09 0.034978265 Up 0.144307796 Ndufa7 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (B14.5a)" K03951|1|1e-37|144|ssc:100517634|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7 - - - - 381201 3092 1.083333333 0.98 -0.144623563 Down 0.144260785 Ap5b1 "adaptor-related protein complex 5, beta 1 subunit" K19022|1|0.0|1375|mmu:381201|AP-5 complex subunit beta-1 GO:0030117//membrane coat GO:0005488//binding GO:0044765//single-organism transport;GO:0045184//establishment of protein localization gi|75677454|ref|NP_001028620.1|/0/AP-5 complex subunit beta-1 [Mus musculus] 238130 8072 0.96 1.06 0.142957954 Up 0.144260785 Dock4 dedicator of cytokinesis 4 K17697|1|0.0|3686|mmu:238130|dedicator of cytokinesis protein 4 GO:0005902//microvillus;GO:0043232;GO:0044444//cytoplasmic part GO:0005102//receptor binding;GO:0019904//protein domain specific binding;GO:0017048//Rho GTPase binding GO:0006935//chemotaxis gi|28972363|dbj|BAC65635.1|/0/mKIAA0716 protein [Mus musculus] 12723 3545 0.983333333 1.08 0.135278859 Up 0.144260785 Clcn1 "chloride channel, voltage-sensitive 1" "K05010|1|0.0|1813|mmu:12723|chloride channel 1, skeletal muscle" GO:0005886//plasma membrane;GO:0034702//ion channel complex GO:0005254//chloride channel activity GO:0015698//inorganic anion transport;GO:0050877//neurological system process;GO:0034220//ion transmembrane transport gi|29789048|ref|NP_038519.1|/0/chloride channel protein 1 [Mus musculus] 21939 1784 1 1.103333333 0.141868716 Up 0.144260785 Cd40 CD40 antigen K03160|1|1e-131|472|mmu:21939|tumor necrosis factor receptor superfamily member 5 GO:0009986//cell surface;GO:0043227//membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0044421;GO:0009986//cell surface;GO:0043227//membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0044421;GO:0009986//cell surface;GO:0043227//membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0044421;GO:0009986//cell surface;GO:0043227//membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0044421;GO:0009986//cell surface;GO:0043227//membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0044421 GO:0044389//ubiquitin-like protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding GO:0043065//positive regulation of apoptotic process;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0043405//regulation of MAP kinase activity;GO:0009612//response to mechanical stimulus;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006952//defense response;GO:0002764//immune response-regulating signaling pathway;GO:0045830//positive regulation of isotype switching;GO:0001819//positive regulation of cytokine production;GO:0030888//regulation of B cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006875//cellular metal ion homeostasis;GO:0032496//response to lipopolysaccharide;GO:0043065//positive regulation of apoptotic process;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0043405//regulation of MAP kinase activity;GO:0009612//response to mechanical stimulus;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006952//defense response;GO:0002764//immune response-regulating signaling pathway;GO:0045830//positive regulation of isotype switching;GO:0001819//positive regulation of cytokine production;GO:0030888//regulation of B cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006875//cellular metal ion homeostasis;GO:0032496//response to lipopolysaccharide;GO:0043065//positive regulation of apoptotic process;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0043405//regulation of MAP kinase activity;GO:0009612//response to mechanical stimulus;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006952//defense response;GO:0002764//immune response-regulating signaling pathway;GO:0045830//positive regulation of isotype switching;GO:0001819//positive regulation of cytokine production;GO:0030888//regulation of B cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006875//cellular metal ion homeostasis;GO:0032496//response to lipopolysaccharide;GO:0043065//positive regulation of apoptotic process;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0043405//regulation of MAP kinase activity;GO:0009612//response to mechanical stimulus;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006952//defense response;GO:0002764//immune response-regulating signaling pathway;GO:0045830//positive regulation of isotype switching;GO:0001819//positive regulation of cytokine production;GO:0030888//regulation of B cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006875//cellular metal ion homeostasis;GO:0032496//response to lipopolysaccharide;GO:0043065//positive regulation of apoptotic process;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0043405//regulation of MAP kinase activity;GO:0009612//response to mechanical stimulus;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006952//defense response;GO:0002764//immune response-regulating signaling pathway;GO:0045830//positive regulation of isotype switching;GO:0001819//positive regulation of cytokine production;GO:0030888//regulation of B cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006875//cellular metal ion homeostasis;GO:0032496//response to lipopolysaccharide gi|70608177|ref|NP_733803.2|/3.80178e-159/tumor necrosis factor receptor superfamily member 5 isoform 5 precursor [Mus musculus] 12523 3310.32 1.086666667 0.983333333 -0.14415701 Down 0.144260785 Cd84 CD84 antigen K06511|1|2e-178|629|mmu:12523|CD84 antigen GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0022610;GO:0022610;GO:0022610 gi|7304955|ref|NP_038517.1|/2.0971e-179/SLAM family member 5 isoform 1 precursor [Mus musculus] 66142 1176 362.4933333 369.2333333 0.026578339 Up 0.14424198 Cox7b cytochrome c oxidase subunit VIIb K02271|1|7e-40|167|mmu:66142|cytochrome c oxidase subunit 7b GO:0005743//mitochondrial inner membrane;GO:0031224//intrinsic component of membrane GO:0015002//heme-copper terminal oxidase activity GO:0044710 "gi|13384754|ref|NP_079655.1|/5.67189e-39/cytochrome c oxidase subunit 7B, mitochondrial precursor [Mus musculus]" 103161 1930 0.2 0.26 0.378511623 Up 0.144223175 Apof apolipoprotein F K03155|1|1e-30|137|pss:102457644|timeless;K02942|3|7e-09|56.6|cfa:100856037|large subunit ribosomal protein LP1 GO:0034358//plasma lipoprotein particle - GO:0030301//cholesterol transport;GO:0006639//acylglycerol metabolic process;GO:0016125//sterol metabolic process gi|19527216|ref|NP_598758.1|/0/apolipoprotein F precursor [Mus musculus] 333789 5731 0.186666667 0.243333333 0.382469637 Up 0.144223175 N4bp2 NEDD4 binding protein 2 K15720|1|0.0|3092|mmu:333789|NEDD4-binding protein 2 [EC:3.-.-.-] - - - gi|568934326|ref|XP_006504069.1|/0/PREDICTED: NEDD4-binding protein 2 isoform X3 [Mus musculus] 104732 3371 0.213333333 0.276666667 0.375039431 Up 0.144223175 4930427A07Rik RIKEN cDNA 4930427A07 gene - - - - gi|74188956|dbj|BAE39248.1|/0/unnamed protein product [Mus musculus] 12531 3060.4 2.46 2.606666667 0.083547791 Up 0.144129151 Cdc25b cell division cycle 25B K05866|1|0.0|1112|mmu:12531|M-phase inducer phosphatase 2 [EC:3.1.3.48] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle GO:0004721//phosphoprotein phosphatase activity;GO:0019900//kinase binding;GO:0004721//phosphoprotein phosphatase activity;GO:0019900//kinase binding GO:0001934//positive regulation of protein phosphorylation;GO:0007127//meiosis I;GO:0032467//positive regulation of cytokinesis;GO:0003006//developmental process involved in reproduction;GO:0000087//mitotic M phase;GO:0001934//positive regulation of protein phosphorylation;GO:0007127//meiosis I;GO:0032467//positive regulation of cytokinesis;GO:0003006//developmental process involved in reproduction;GO:0000087//mitotic M phase gi|161621261|ref|NP_001104545.1|/0/M-phase inducer phosphatase 2 isoform b [Mus musculus] 17161 4161 2.906666667 2.756666667 -0.076440806 Down 0.144129151 Maoa monoamine oxidase A K00274|1|0.0|1066|cge:100760815|monoamine oxidase [EC:1.4.3.4] GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane "GO:0043169//cation binding;GO:0000166//nucleotide binding;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor" GO:0006576//cellular biogenic amine metabolic process;GO:0042133//neurotransmitter metabolic process;GO:0042430//indole-containing compound metabolic process;GO:0042417//dopamine metabolic process gi|625217725|ref|XP_003510347.2|/0/PREDICTED: amine oxidase [flavin-containing] A isoform X1 [Cricetulus griseus] 735265 109 2.67 2.523333333 -0.081508942 Down 0.144129151 Mir703 microRNA 703 - - - - - 53627 1683.28 3.013333333 2.86 -0.075345125 Down 0.144129151 Porcn porcupine homolog (Drosophila) K00181|1|1e-173|538|rno:317368|O-palmitoleoyl transferase [EC:2.3.1.250] GO:0008328//ionotropic glutamate receptor complex;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0008328//ionotropic glutamate receptor complex;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0008328//ionotropic glutamate receptor complex;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0008328//ionotropic glutamate receptor complex;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0008328//ionotropic glutamate receptor complex;GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0016740//transferase activity;GO:0016740//transferase activity;GO:0016740//transferase activity;GO:0016740//transferase activity;GO:0016740//transferase activity GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway gi|537131620|gb|ERE65644.1|/0/putative protein-cysteine N-palmitoyltransferase porcupine isoform 1 [Cricetulus griseus] 227545 3499.61 7.97 7.686666667 -0.052221617 Down 0.144082139 Proser2 proline and serine rich 2 - - - - "gi|148676030|gb|EDL07977.1|/0/RIKEN cDNA 5430407P10, isoform CRA_a, partial [Mus musculus]" 228536 4428 7.66 7.38 -0.053723576 Down 0.144082139 Bahd1 bromo adjacent homology domain containing 1 K17963|1|3e-07|60.8|phi:102099208|peroxisome proliferator-activated receptor gamma coactivator-related protein 1;K09187|2|1e-06|59.3|cfa:486558|histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43];K05628|3|1e-06|58.9|bta:535394|arginine-glutamic acid dipeptide repeats protein;K08867|5|6e-06|56.6|gga:777580|WNK lysine deficient protein kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043232 GO:0005488//binding "GO:0031497//chromatin assembly;GO:0006351//transcription, DNA-templated" gi|568916503|ref|XP_006499328.1|/0/PREDICTED: bromo adjacent homology domain-containing 1 protein isoform X1 [Mus musculus] 26932 4841 8.87 8.586666667 -0.046835917 Down 0.144082139 Ppp2r5e "protein phosphatase 2, regulatory subunit B', epsilon" K11584|1|0.0|827|gfr:102039573|serine/threonine-protein phosphatase 2A regulatory subunit B' GO:0044424;GO:0008287//protein serine/threonine phosphatase complex;GO:0043227//membrane-bounded organelle GO:0005488//binding;GO:0019888//protein phosphatase regulator activity GO:0007154//cell communication gi|60360208|dbj|BAD90335.1|/0/mKIAA4006 protein [Mus musculus] 72129 4122 8.74 8.46 -0.046975616 Down 0.144082139 Pex13 peroxisomal biogenesis factor 13 K13344|1|0.0|691|mmu:72129|peroxin-13 GO:0031231//intrinsic component of peroxisomal membrane - GO:0007017//microtubule-based process;GO:0009062//fatty acid catabolic process;GO:0016558//protein import into peroxisome matrix;GO:0021987//cerebral cortex development;GO:0007631//feeding behavior;GO:0016477//cell migration;GO:0044708//single-organism behavior gi|31543471|ref|NP_076140.2|/0/peroxisomal membrane protein PEX13 [Mus musculus] 20849 2672 0.07 0.12 0.777607579 Up 0.144016323 Stat4 signal transducer and activator of transcription 4 K11222|1|0.0|1441|mmu:20849|signal transducer and activator of transcription 4 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0060089;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0043566//structure-specific DNA binding;GO:0060089;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0043566//structure-specific DNA binding" GO:0001525//angiogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0001935//endothelial cell proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006464//cellular protein modification process;GO:0035295//tube development;GO:0043331//response to dsRNA;GO:0001525//angiogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0001935//endothelial cell proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006464//cellular protein modification process;GO:0035295//tube development;GO:0043331//response to dsRNA gi|568906025|ref|XP_006495877.1|/0/PREDICTED: signal transducer and activator of transcription 4 isoform X1 [Mus musculus] 236930 4198 0.063333333 0.11 0.796466606 Up 0.144016323 Ercc6l excision repair cross-complementing rodent repair deficiency complementation group 6 like K20093|1|0.0|2223|mmu:236930|DNA excision repair protein ERCC-6-like [EC:3.6.4.12] "GO:0000775//chromosome, centromeric region" GO:0003676//nucleic acid binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0000087//mitotic M phase gi|27414501|ref|NP_666347.2|/0/DNA excision repair protein ERCC-6-like [Mus musculus] 69282 808 0.07 0.12 0.777607579 Up 0.144016323 1700001J03Rik RIKEN cDNA 1700001J03 gene K08732|1|5e-14|80.5|amj:102566192|ral guanine nucleotide dissociation stimulator - - - gi|56606117|ref|NP_001008547.1|/1.1207e-126/uncharacterized protein LOC69282 [Mus musculus] 232983 760 0.073333333 0.126666667 0.788495895 Up 0.144016323 Cxcl17 chemokine (C-X-C motif) ligand 17 - - - GO:0042221//response to chemical;GO:0048869//cellular developmental process gi|133891727|ref|NP_705804.2|/9.50006e-53/VEGF coregulated chemokine 1 precursor [Mus musculus] 29810 2607 307.0466667 301.3833333 -0.026858304 Down 0.143988115 Bag3 BCL2-associated athanogene 3 K09557|1|0.0|977|mmu:29810|BCL2-associated athanogene 3 GO:0031674//I band;GO:0042995//cell projection;GO:0016020//membrane GO:0005515//protein binding GO:0007417//central nervous system development;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0009612//response to mechanical stimulus gi|115270960|ref|NP_038891.4|/0/BAG family molecular chaperone regulator 3 [Mus musculus] 77862 951.84 17.41666667 16.98 -0.036632078 Down 0.143969311 Thyn1 thymocyte nuclear protein 1 - - - - - 233863 6891 17.26 16.82 -0.037254759 Down 0.143969311 Gtf3c1 general transcription factor III C 1 K15199|1|0.0|3712|mmu:233863|general transcription factor 3C polypeptide 1 GO:0000127//transcription factor TFIIIC complex GO:0003676//nucleic acid binding GO:0010467//gene expression gi|46402235|ref|NP_997122.1|/0/general transcription factor 3C polypeptide 1 [Mus musculus] 100072 6628.77 16.31666667 15.88 -0.039135447 Down 0.143969311 Camta1 calmodulin binding transcription activator 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|125719159|ref|NP_001075026.1|/0/calmodulin-binding transcription activator 1 isoform 1 [Mus musculus] 77110 3550 17.21666667 17.65333333 0.036134773 Up 0.143969311 Gpbp1l1 GC-rich promoter binding protein 1-like 1 - GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|26345986|dbj|BAC36644.1|/0/unnamed protein product [Mus musculus] 75624 2549 16.29333333 16.73666667 0.03873044 Up 0.143969311 Metap1 methionyl aminopeptidase 1 K01265|1|0.0|815|mmu:75624|methionyl aminopeptidase [EC:3.4.11.18] GO:0044424 GO:0043169//cation binding;GO:0008238//exopeptidase activity;GO:0008237//metallopeptidase activity GO:0018193//peptidyl-amino acid modification;GO:0006412//translation gi|28202007|ref|NP_780433.1|/0/methionine aminopeptidase 1 [Mus musculus] 67184 1266 278.2966667 272.87 -0.028409839 Down 0.143950506 Ndufa13 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13" K11353|1|3e-80|301|mmu:67184|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13 GO:0031981//nuclear lumen;GO:0005746//mitochondrial respiratory chain;GO:0031224//intrinsic component of membrane GO:0032550;GO:0050136//NADH dehydrogenase (quinone) activity "GO:0051234//establishment of localization;GO:0006351//transcription, DNA-templated;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0006412//translation;GO:0006091//generation of precursor metabolites and energy;GO:0044710;GO:0007165//signal transduction;GO:0012502//induction of programmed cell death;GO:0016049//cell growth" gi|12963633|ref|NP_075801.1|/2.80454e-79/NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 [Mus musculus] 69137 1988 0.203333333 0.263333333 0.373043411 Up 0.143912896 Vstm5 V-set and transmembrane domain containing 5 - GO:0031224//intrinsic component of membrane - - gi|58037147|ref|NP_081231.1|/2.1514e-101/V-set and transmembrane domain-containing protein 5 precursor [Mus musculus] 241062 10579 0.206666667 0.266666667 0.367731785 Up 0.143912896 Pgap1 post-GPI attachment to proteins 1 K05294|1|0.0|1765|mmu:241062|glycosylphosphatidylinositol deacylase [EC:3.-.-.-] GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane "GO:0016788//hydrolase activity, acting on ester bonds" GO:0003002//regionalization;GO:0015791//polyol transport;GO:0050954//sensory perception of mechanical stimulus;GO:0090304;GO:0009798//axis specification;GO:0006497//protein lipidation;GO:0015031//protein transport;GO:0009790//embryo development gi|254028203|ref|NP_001156786.1|/0/GPI inositol-deacylase [Mus musculus] 56620 1143 1.24 1.346666667 0.119052672 Up 0.143884689 Clec4n "C-type lectin domain family 4, member n" K17514|1|4e-101|370|mmu:56620|C-type lectin domain family 6 member A GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0006952//defense response;GO:0050663//cytokine secretion;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006952//defense response;GO:0050663//cytokine secretion;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006952//defense response;GO:0050663//cytokine secretion;GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|298358452|ref|NP_001177250.1|/1.95342e-105/C-type lectin domain family 6 member A isoform 3 [Mus musculus] 102465636 73 1.39 1.283333333 -0.115188938 Down 0.143884689 Mir7051 microRNA 7051 - - - - - 320472 6315 1.353333333 1.466666667 0.116023796 Up 0.143884689 Ppm1e protein phosphatase 1E (PP2C domain containing) K17501|1|0.0|1246|mmu:320472|protein phosphatase 1E [EC:3.1.3.16] GO:0032991//macromolecular complex;GO:0031981//nuclear lumen GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity GO:0006470//protein dephosphorylation;GO:0001933//negative regulation of protein phosphorylation;GO:0032233//positive regulation of actin filament bundle assembly;GO:0042493//response to drug gi|28972600|dbj|BAC65716.1|/0/mKIAA1072 protein [Mus musculus] 83921 6620 1.383333333 1.273333333 -0.119538698 Down 0.143884689 Tmem2 transmembrane protein 2 K19031|1|0.0|880|lcm:102367458|cell migration-inducing and hyaluronan-binding protein [EC:3.2.1.35] GO:0031224//intrinsic component of membrane - GO:0032502//developmental process gi|76253922|ref|NP_001028931.1|/0/transmembrane protein 2 [Mus musculus] 380993 4414 1.33 1.22 -0.124545098 Down 0.143884689 Zfat zinc finger and AT hook domain containing K09228|1|1e-58|231|bfo:BRAFLDRAFT_118280|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0030097//hemopoiesis;GO:0001892//embryonic placenta development;GO:0006351//transcription, DNA-templated;GO:0030097//hemopoiesis;GO:0001892//embryonic placenta development;GO:0006351//transcription, DNA-templated" gi|568992767|ref|XP_006521188.1|/0/PREDICTED: zinc finger protein ZFAT isoform X2 [Mus musculus] 666173 13380 1.33 1.443333333 0.117978279 Up 0.143884689 Vps13b vacuolar protein sorting 13B K19526|1|0.0|7820|mmu:666173|vacuolar protein sorting-associated protein 13B - - - gi|194394221|ref|NP_796125.2|/0/vacuolar protein sorting-associated protein 13B [Mus musculus] 54650 7743 1.256666667 1.366666667 0.121059386 Up 0.143884689 Sfmbt1 Scm-like with four mbt domains 1 K11461|1|7e-33|147|api:100161168|polycomb protein SCMH1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|9507089|ref|NP_062333.1|/0/scm-like with four MBT domains protein 1 [Mus musculus] 14283 1705 1.276666667 1.383333333 0.115766944 Up 0.143884689 Fosl1 fos-like antigen 1 K04502|1|2e-73|279|mmu:14283|fos-like antigen 1 GO:0097060//synaptic membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0044444//cytoplasmic part GO:0003677//DNA binding GO:0044703;GO:0009605//response to external stimulus;GO:0007028//cytoplasm organization;GO:0007611//learning or memory;GO:0001568//blood vessel development;GO:0008283//cell proliferation;GO:0046683//response to organophosphorus;GO:0006915//apoptotic process;GO:0000302//response to reactive oxygen species;GO:0051384//response to glucocorticoid;GO:0043009//chordate embryonic development;GO:0007154//cell communication;GO:0051726//regulation of cell cycle;GO:0009628//response to abiotic stimulus;GO:0044093 gi|74202982|dbj|BAE26198.1|/1.72264e-72/unnamed protein product [Mus musculus] 29817 1121.67 225.1433333 220 -0.033340235 Down 0.143865884 Igfbp7 insulin-like growth factor binding protein 7 K08784|1|2e-14|82.8|xtr:780187|HtrA serine peptidase 1 [EC:3.4.21.-] GO:0044421;GO:0044421 GO:0019838//growth factor binding;GO:0019838//growth factor binding GO:0022610;GO:0016049//cell growth;GO:0051384//response to glucocorticoid;GO:0043583//ear development;GO:0006694//steroid biosynthetic process;GO:0006950//response to stress;GO:0022610;GO:0044763;GO:0051384//response to glucocorticoid;GO:0043583//ear development;GO:0006694//steroid biosynthetic process;GO:0006950//response to stress gi|226958453|ref|NP_001152990.1|/3.40411e-135/insulin-like growth factor-binding protein 7 isoform 1 precursor [Mus musculus] 665005 3938 0.053333333 0.016666667 -1.678071905 Down 0.14380947 Gm7444 ring finger protein 19A pseudogene K11972|1|0.0|1156|mmu:30945|E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.27] GO:0016020//membrane;GO:0044424 GO:0046872//metal ion binding - "gi|148676876|gb|EDL08823.1|/0/ring finger protein (C3HC4 type) 19, isoform CRA_a [Mus musculus]" 14194 1644 202.03 206.9666667 0.034828892 Up 0.14380947 Fh1 fumarate hydratase 1 "K01679|1|0.0|943|mmu:14194|fumarate hydratase, class II [EC:4.2.1.2]" GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0016836//hydro-lyase activity GO:0009060//aerobic respiration;GO:0001894//tissue homeostasis;GO:0043648//dicarboxylic acid metabolic process "gi|226823367|ref|NP_034339.2|/0/fumarate hydratase, mitochondrial precursor [Mus musculus]" 225998 8808 0.06 0.016666667 -1.847996907 Down 0.14380947 Rorb RAR-related orphan receptor beta K08533|1|0.0|897|mmu:225998|RAR-related orphan receptor beta GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0004930//G-protein coupled receptor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0004930//G-protein coupled receptor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0004930//G-protein coupled receptor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding" "GO:0006351//transcription, DNA-templated;GO:0009755//hormone-mediated signaling pathway;GO:0050953//sensory perception of light stimulus;GO:0001754//eye photoreceptor cell differentiation;GO:0006351//transcription, DNA-templated;GO:0009755//hormone-mediated signaling pathway;GO:0050953//sensory perception of light stimulus;GO:0001754//eye photoreceptor cell differentiation;GO:0006351//transcription, DNA-templated;GO:0009755//hormone-mediated signaling pathway;GO:0050953//sensory perception of light stimulus;GO:0001754//eye photoreceptor cell differentiation" gi|112821692|ref|NP_666207.3|/0/nuclear receptor ROR-beta isoform 2 [Mus musculus] 432450 3205 0.063333333 0.02 -1.662965013 Down 0.14380947 Nkain2 Na+/K+ transporting ATPase interacting 2 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|226437655|ref|NP_001013429.2|/5.09401e-122/sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 long isoform [Mus musculus] 223645 3372 0.06 0.02 -1.584962501 Down 0.14380947 Mroh6 maestro heat-like repeat family member 6 - - - - gi|541862097|ref|NP_001269372.1|/0/maestro heat-like repeat-containing protein family member 6 [Mus musculus] 19739 7642 0.063333333 0.02 -1.662965013 Down 0.14380947 Rgs9 regulator of G-protein signaling 9 K13765|1|0.0|1294|mmu:19739|regulator of G-protein signaling 9 - - - "gi|148702403|gb|EDL34350.1|/0/regulator of G-protein signaling 9, isoform CRA_a, partial [Mus musculus]" 259172 4274 0.056666667 0.016666667 -1.765534746 Down 0.14380947 Mfrp membrane frizzled-related protein K05502|1|1e-37|161|xma:102230322|bone morphogenetic protein 1 [EC:3.4.24.19] - - - - 215001 2536 0.286666667 0.223333333 -0.360175564 Down 0.143781263 Wfikkn1 "WAP, FS, Ig, KU, and NTR-containing protein 1" K03909|1|1e-13|81.3|mze:101471591|tissue factor pathway inhibitor GO:0044421 GO:0004866//endopeptidase inhibitor activity GO:0051346//negative regulation of hydrolase activity;GO:0006508//proteolysis "gi|162462114|ref|NP_001093924.1|/0/WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 precursor [Mus musculus]" 100526796 1223 0.29 0.226666667 -0.355480655 Down 0.143781263 Cahm colon adenocarcinoma hypermethylated RNA - - - - - 12111 2423 195.0933333 199.6666667 0.033429023 Up 0.143668434 Bgn biglycan K08118|1|0.0|728|mmu:12111|biglycan - - - - 319556 1843 0.133333333 0.08 -0.736965594 Down 0.143659032 A330041J22Rik RIKEN cDNA A330041J22 gene - - - - - 791318 1509 0.073333333 0.123333333 0.750021747 Up 0.143659032 Gm10125 predicted gene 10125 - - - - - 111975 4778 0.13 0.076666667 -0.761840263 Down 0.143659032 Igf2os "insulin-like growth factor 2, opposite strand" K04526|1|3e-18|97.8|umr:103671056|insulin - - - "gi|148686231|gb|EDL18178.1|/4.17479e-147/mCG146197, partial [Mus musculus]" 236899 4864 0.123333333 0.073333333 -0.750021747 Down 0.143659032 Pcyt1b "phosphate cytidylyltransferase 1, choline, beta isoform" K00968|1|0.0|664|mmu:236899|choline-phosphate cytidylyltransferase [EC:2.7.7.15] GO:0043231//intracellular membrane-bounded organelle GO:0070567 GO:0008585//female gonad development;GO:0006644//phospholipid metabolic process;GO:0048232//male gamete generation gi|46877071|ref|NP_997593.1|/0/choline-phosphate cytidylyltransferase B isoform 1 [Mus musculus] 22215 4971.31 4.856666667 4.643333333 -0.064805619 Down 0.143470984 Ube3a ubiquitin protein ligase E3A K10587|1|0.0|1593|mmu:22215|ubiquitin-protein ligase E3 A [EC:2.3.2.26] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0003712//transcription cofactor activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0005488//binding;GO:0003712//transcription cofactor activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0005488//binding GO:0000209//protein polyubiquitination;GO:0006366//transcription from RNA polymerase II promoter;GO:0008585//female gonad development;GO:0009967//positive regulation of signal transduction;GO:0006897//endocytosis;GO:0019941//modification-dependent protein catabolic process;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0000209//protein polyubiquitination;GO:0006366//transcription from RNA polymerase II promoter;GO:0008585//female gonad development;GO:0009967//positive regulation of signal transduction;GO:0006897//endocytosis;GO:0019941//modification-dependent protein catabolic process;GO:0030518//intracellular steroid hormone receptor signaling pathway gi|76880494|ref|NP_035798.2|/0/ubiquitin-protein ligase E3A isoform 2 [Mus musculus] 53357 3401.93 4.673333333 4.883333333 0.063414315 Up 0.143470984 Pla2g6 "phospholipase A2, group VI" K16343|1|0.0|1471|rno:360426|calcium-independent phospholipase A2 [EC:3.1.1.4] GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part GO:0004623//phospholipase A2 activity;GO:0005515//protein binding;GO:0004623//phospholipase A2 activity;GO:0005515//protein binding;GO:0004623//phospholipase A2 activity;GO:0005515//protein binding;GO:0004623//phospholipase A2 activity;GO:0005515//protein binding "GO:0032024//positive regulation of insulin secretion;GO:0010822//positive regulation of mitochondrion organization;GO:1901019//regulation of calcium ion transmembrane transporter activity;GO:0006887//exocytosis;GO:0042311//vasodilation;GO:0035249//synaptic transmission, glutamatergic;GO:0007611//learning or memory;GO:0046513//ceramide biosynthetic process;GO:0032305//positive regulation of icosanoid secretion;GO:0042221//response to chemical;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0033554//cellular response to stress;GO:0007565//female pregnancy;GO:0014848;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0032024//positive regulation of insulin secretion;GO:0010822//positive regulation of mitochondrion organization;GO:1901019//regulation of calcium ion transmembrane transporter activity;GO:0006887//exocytosis;GO:0042311//vasodilation;GO:0035249//synaptic transmission, glutamatergic;GO:0007611//learning or memory;GO:0046513//ceramide biosynthetic process;GO:0032305//positive regulation of icosanoid secretion;GO:0042221//response to chemical;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0033554//cellular response to stress;GO:0007565//female pregnancy;GO:0014848;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0032024//positive regulation of insulin secretion;GO:0010822//positive regulation of mitochondrion organization;GO:1901019//regulation of calcium ion transmembrane transporter activity;GO:0006887//exocytosis;GO:0042311//vasodilation;GO:0035249//synaptic transmission, glutamatergic;GO:0007611//learning or memory;GO:0046513//ceramide biosynthetic process;GO:0032305//positive regulation of icosanoid secretion;GO:0042221//response to chemical;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0033554//cellular response to stress;GO:0007565//female pregnancy;GO:0014848;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0032024//positive regulation of insulin secretion;GO:0010822//positive regulation of mitochondrion organization;GO:1901019//regulation of calcium ion transmembrane transporter activity;GO:0006887//exocytosis;GO:0042311//vasodilation;GO:0035249//synaptic transmission, glutamatergic;GO:0007611//learning or memory;GO:0046513//ceramide biosynthetic process;GO:0032305//positive regulation of icosanoid secretion;GO:0042221//response to chemical;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0033554//cellular response to stress;GO:0007565//female pregnancy;GO:0014848;GO:0051480//regulation of cytosolic calcium ion concentration" "gi|148672710|gb|EDL04657.1|/0/phospholipase A2, group VI, isoform CRA_b, partial [Mus musculus]" 114893 4474 5.106666667 4.896666667 -0.060581901 Down 0.143470984 Dcun1d1 "DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)" K17822|1|3e-148|529|mmu:114893|DCN1-like protein 1/2 GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - gi|635083686|ref|XP_007970173.1|/1.31595e-147/PREDICTED: DCN1-like protein 1 isoform X4 [Chlorocebus sabaeus] 101358 4219 4.903333333 5.116666667 0.061441409 Up 0.143470984 Fbxl14 F-box and leucine-rich repeat protein 14 K10280|1|0.0|797|lve:103085953|F-box and leucine-rich repeat protein 14 GO:0044424 GO:0019787//ubiquitin-like protein transferase activity GO:0016567//protein ubiquitination gi|823420267|ref|XP_004406931.2|/0/PREDICTED: F-box/LRR-repeat protein 14 isoform X1 [Odobenus rosmarus divergens] 105348 3557 4.71 4.916666667 0.061953489 Up 0.143470984 Golm1 golgi membrane protein 1 K17751|1|7e-09|66.2|isc:IscW_ISCW001340|myosin heavy chain 6/7;K20478|2|3e-07|60.8|dre:557772|golgin subfamily B member 1;K18626|3|8e-07|59.3|mdo:100019329|trichohyalin GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0006996//organelle organization;GO:0006629//lipid metabolic process;GO:0006996//organelle organization;GO:0006629//lipid metabolic process gi|78190500|ref|NP_001030294.1|/0/Golgi membrane protein 1 [Mus musculus] 68988 3143 7.363333333 7.636666667 0.05258404 Up 0.143405168 Prpf31 pre-mRNA processing factor 31 K12844|1|0.0|822|mmu:68988|U4/U6 small nuclear ribonucleoprotein PRP31 - - - - 67684 3327 7.446666667 7.18 -0.052610936 Down 0.143405168 Luc7l3 LUC7-like 3 (S. cerevisiae) K13212|1|2e-32|144|mze:101478282|RNA-binding protein Luc7-like 2 GO:0005924//cell-substrate adherens junction;GO:0016604//nuclear body;GO:0016020//membrane GO:0003723//RNA binding GO:0050896//response to stimulus;GO:0012501//programmed cell death;GO:0006396//RNA processing gi|926717435|ref|XP_013827859.1|/3.11298e-130/PREDICTED: luc7-like protein 3 isoform X4 [Capra hircus] 18754 6254 7.463333333 7.196666667 -0.052491285 Down 0.143405168 Prkce "protein kinase C, epsilon" K18050|1|0.0|1488|mmu:18754|novel protein kinase C epsilon type [EC:2.7.11.13] GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0030545;GO:0030234//enzyme regulator activity;GO:0004697//protein kinase C activity;GO:0019900//kinase binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0043169//cation binding;GO:0043168//anion binding;GO:0003779//actin binding "GO:0010523//negative regulation of calcium ion transport into cytosol;GO:0010810//regulation of cell-substrate adhesion;GO:0001932//regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0034142//toll-like receptor 4 signaling pathway;GO:0010761//fibroblast migration;GO:0051560//mitochondrial calcium ion homeostasis;GO:0045471//response to ethanol;GO:0006629//lipid metabolic process;GO:0002275//myeloid cell activation involved in immune response;GO:0014072//response to isoquinoline alkaloid;GO:0010676;GO:0001666//response to hypoxia;GO:0045837//negative regulation of membrane potential;GO:0009896;GO:0051047//positive regulation of secretion;GO:0007626//locomotory behavior;GO:0007166//cell surface receptor signaling pathway;GO:0051283//negative regulation of sequestering of calcium ion;GO:0010631//epithelial cell migration;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0030041//actin filament polymerization;GO:0050796//regulation of insulin secretion;GO:0000165//MAPK cascade;GO:0032467//positive regulation of cytokinesis;GO:0032228//regulation of synaptic transmission, GABAergic" gi|6755084|ref|NP_035234.1|/0/protein kinase C epsilon type [Mus musculus] 14814 4383 0.6 0.523333333 -0.197232347 Down 0.143348753 Grin2d "glutamate receptor, ionotropic, NMDA2D (epsilon 4)" "K05212|1|0.0|1964|mmu:14814|glutamate receptor ionotropic, NMDA 2D" GO:0045202//synapse;GO:0008328//ionotropic glutamate receptor complex GO:0004970//ionotropic glutamate receptor activity;GO:0005244//voltage-gated ion channel activity;GO:0016597//amino acid binding GO:0006810//transport;GO:0007215//glutamate receptor signaling pathway;GO:0051899//membrane depolarization;GO:0019233//sensory perception of pain;GO:0007626//locomotory behavior;GO:0007270//neuron-neuron synaptic transmission "gi|144922606|ref|NP_032198.2|/0/glutamate receptor ionotropic, NMDA 2D precursor [Mus musculus]" 338362 4284 0.56 0.643333333 0.200139614 Up 0.143348753 Ust uronyl-2-sulfotransferase K03193|1|0.0|778|mmu:338362|dermatan/chondrotin sulfate uronyl 2-O-sulfotransferase UST [EC:2.8.2.-] GO:0031224//intrinsic component of membrane;GO:0012505//endomembrane system "GO:0016782//transferase activity, transferring sulfur-containing groups" GO:0006024//glycosaminoglycan biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0006464//cellular protein modification process gi|110556631|ref|NP_796361.2|/0/uronyl 2-sulfotransferase [Mus musculus] 233765 4730.85 0.61 0.53 -0.202816883 Down 0.143348753 Plekha7 "pleckstrin homology domain containing, family A member 7" K17536|1|3e-10|71.2|mze:101484241|connector enhancer of kinase suppressor of Ras 2 GO:0005815//microtubule organizing center;GO:0005913//cell-cell adherens junction GO:0005515//protein binding GO:0016337//single organismal cell-cell adhesion;GO:0045217//cell-cell junction maintenance gi|755522470|ref|XP_011240049.1|/0/PREDICTED: pleckstrin homology domain-containing family A member 7 isoform X1 [Mus musculus] 11848 2036.69 160.54 164.1533333 0.032111243 Up 0.143273534 Rhoa ras homolog family member A "K04513|1|2e-108|395|cge:100762797|Ras homolog gene family, member A" GO:0032155;GO:0043231//intracellular membrane-bounded organelle;GO:0001726//ruffle;GO:0016020//membrane;GO:0043005//neuron projection;GO:0043232;GO:0005911//cell-cell junction;GO:0044444//cytoplasmic part;GO:0032155;GO:0043231//intracellular membrane-bounded organelle;GO:0001726//ruffle;GO:0016020//membrane;GO:0043005//neuron projection;GO:0043232;GO:0005911//cell-cell junction;GO:0044444//cytoplasmic part;GO:0032155;GO:0043231//intracellular membrane-bounded organelle;GO:0001726//ruffle;GO:0016020//membrane;GO:0043005//neuron projection;GO:0043232;GO:0005911//cell-cell junction;GO:0044444//cytoplasmic part GO:0017111//nucleoside-triphosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0032550 GO:0032506//cytokinetic process;GO:0031589//cell-substrate adhesion;GO:0007043//cell-cell junction assembly;GO:0006939//smooth muscle contraction;GO:0006950//response to stress;GO:0007409//axonogenesis;GO:0048017//inositol lipid-mediated signaling;GO:0001503//ossification;GO:0009154//purine ribonucleotide catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0007052//mitotic spindle organization;GO:0097305//response to alcohol;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0006935//chemotaxis;GO:0033687//osteoblast proliferation;GO:0030041//actin filament polymerization;GO:0001775//cell activation;GO:0032233//positive regulation of actin filament bundle assembly;GO:0031960//response to corticosteroid;GO:0014706//striated muscle tissue development;GO:0031334//positive regulation of protein complex assembly;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0032467//positive regulation of cytokinesis;GO:0032570//response to progesterone;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0016477//cell migration;GO:0009746;GO:0009968//negative regulation of signal transduction;GO:0006412//translation;GO:0001101//response to acid chemical;GO:0019229//regulation of vasoconstriction;GO:0016049//cell growth;GO:0006366//transcription from RNA polymerase II promoter;GO:0030832//regulation of actin filament length;GO:0010975//regulation of neuron projection development;GO:0007265//Ras protein signal transduction;GO:0006816//calcium ion transport;GO:0007599//hemostasis;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0032506//cytokinetic process;GO:0031589//cell-substrate adhesion;GO:0007043//cell-cell junction assembly;GO:0006939//smooth muscle contraction;GO:0006950//response to stress;GO:0007409//axonogenesis;GO:0048017//inositol lipid-mediated signaling;GO:0001503//ossification;GO:0009154//purine ribonucleotide catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0007052//mitotic spindle organization;GO:0097305//response to alcohol;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0006935//chemotaxis;GO:0033687//osteoblast proliferation;GO:0030041//actin filament polymerization;GO:0001775//cell activation;GO:0032233//positive regulation of actin filament bundle assembly;GO:0031960//response to corticosteroid;GO:0014706//striated muscle tissue development;GO:0031334//positive regulation of protein complex assembly;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0032467//positive regulation of cytokinesis;GO:0032570//response to progesterone;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0016477//cell migration;GO:0009746;GO:0009968//negative regulation of signal transduction;GO:0006412//translation;GO:0001101//response to acid chemical;GO:0019229//regulation of vasoconstriction;GO:0016049//cell growth;GO:0006366//transcription from RNA polymerase II promoter;GO:0030832//regulation of actin filament length;GO:0010975//regulation of neuron projection development;GO:0007265//Ras protein signal transduction;GO:0006816//calcium ion transport;GO:0007599//hemostasis;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0032506//cytokinetic process;GO:0031589//cell-substrate adhesion;GO:0007043//cell-cell junction assembly;GO:0006939//smooth muscle contraction;GO:0006950//response to stress;GO:0007409//axonogenesis;GO:0048017//inositol lipid-mediated signaling;GO:0001503//ossification;GO:0009154//purine ribonucleotide catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0007052//mitotic spindle organization;GO:0097305//response to alcohol;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0006935//chemotaxis;GO:0033687//osteoblast proliferation;GO:0030041//actin filament polymerization;GO:0001775//cell activation;GO:0032233//positive regulation of actin filament bundle assembly;GO:0031960//response to corticosteroid;GO:0014706//striated muscle tissue development;GO:0031334//positive regulation of protein complex assembly;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0032467//positive regulation of cytokinesis;GO:0032570//response to progesterone;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0016477//cell migration;GO:0009746;GO:0009968//negative regulation of signal transduction;GO:0006412//translation;GO:0001101//response to acid chemical;GO:0019229//regulation of vasoconstriction;GO:0016049//cell growth;GO:0006366//transcription from RNA polymerase II promoter;GO:0030832//regulation of actin filament length;GO:0010975//regulation of neuron projection development;GO:0007265//Ras protein signal transduction;GO:0006816//calcium ion transport;GO:0007599//hemostasis;GO:0030518//intracellular steroid hormone receptor signaling pathway gi|16923986|ref|NP_476473.1|/1.49325e-107/transforming protein RhoA precursor [Rattus norvegicus] 12476 1797.38 159.69 156.0933333 -0.03286505 Down 0.143264132 Cd151 CD151 antigen K06537|1|6e-123|443|mmu:12476|CD151 antigen GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0042110//T cell activation;GO:0048870//cell motility;GO:0042110//T cell activation;GO:0048870//cell motility;GO:0042110//T cell activation;GO:0048870//cell motility gi|161353452|ref|NP_033972.2|/6.10674e-122/CD151 antigen [Mus musculus] 67016 5951 3.563333333 3.39 -0.071942174 Down 0.143235925 Tbc1d2b "TBC1 domain family, member 2B" K20166|1|0.0|1846|mmu:67016|TBC1 domain family member 2B GO:0044464 GO:0008289//lipid binding - gi|37360210|dbj|BAC98083.1|/0/mKIAA1055 protein [Mus musculus] 71726 3611 3.313333333 3.48 0.070803955 Up 0.143235925 Smug1 single-strand selective monofunctional uracil DNA glycosylase K10800|1|3e-137|492|mmu:71726|single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0000702//oxidized base lesion DNA N-glycosylase activity;GO:0004844//uracil DNA N-glycosylase activity GO:0006281//DNA repair "gi|148671991|gb|EDL03938.1|/3.17351e-144/single-strand selective monofunctional uracil DNA glycosylase, isoform CRA_b, partial [Mus musculus]" 246277 2265 3.36 3.53 0.07120695 Up 0.143235925 Csad cysteine sulfinic acid decarboxylase K01594|1|0.0|939|mmu:246277|sulfinoalanine decarboxylase [EC:4.1.1.29] GO:0044444//cytoplasmic part GO:0016831//carboxy-lyase activity;GO:0043168//anion binding GO:0019448//L-cysteine catabolic process;GO:0019530//taurine metabolic process gi|21450351|ref|NP_659191.1|/0/cysteine sulfinic acid decarboxylase [Mus musculus] 238023 2055.76 3.253333333 3.42 0.072077678 Up 0.143235925 Hexdc "hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing" K14459|1|0.0|674|mmu:238023|hexosaminidase [EC:3.2.1.52] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0015929//hexosaminidase activity;GO:0015929//hexosaminidase activity GO:0044238//primary metabolic process;GO:0044238//primary metabolic process gi|225703121|ref|NP_001001333.2|/0/hexosaminidase D isoform 2 [Mus musculus] 12124 943 3.73 3.556666667 -0.06864986 Down 0.143235925 Bik BCL2-interacting killer K18452|1|7e-74|279|mmu:12124|Bcl-2-interacting killer GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031967 GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding GO:0012502//induction of programmed cell death;GO:0010822//positive regulation of mitochondrion organization;GO:0048232//male gamete generation;GO:0032461//positive regulation of protein oligomerization;GO:0008406//gonad development gi|568991178|ref|XP_006520417.1|/7.68096e-75/PREDICTED: bcl-2-interacting killer isoform X3 [Mus musculus] 14155 6505 3.37 3.2 -0.074676686 Down 0.143235925 Fem1b feminization 1 homolog b (C. elegans) K10349|1|0.0|1248|mmu:14155|Fem-1 homolog b GO:0031981//nuclear lumen GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0019787//ubiquitin-like protein transferase activity GO:0060740//prostate gland epithelium morphogenesis;GO:0006915//apoptotic process;GO:0002070//epithelial cell maturation;GO:1901976//regulation of cell cycle checkpoint;GO:0031396//regulation of protein ubiquitination gi|6753840|ref|NP_034323.1|/0/protein fem-1 homolog B [Mus musculus] 74375 4138 3.533333333 3.366666667 -0.069708972 Down 0.143235925 Gcc1 golgi coiled coil 1 K20281|1|0.0|1100|mmu:74375|GRIP and coiled-coil domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0005488//binding - gi|268370067|ref|NP_083176.3|/0/GRIP and coiled-coil domain-containing protein 1 [Mus musculus] 15204 15363 3.563333333 3.393333333 -0.070524292 Down 0.143235925 Herc2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 K10595|1|0.0|8825|mmu:15204|E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26] - - - - 17760 2487.33 3.743333333 3.916666667 0.065302829 Up 0.143235925 Map6 microtubule-associated protein 6 K10432|1|0.0|973|mmu:17760|microtubule-associated protein 6 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0007019//microtubule depolymerization;GO:0007019//microtubule depolymerization;GO:0007019//microtubule depolymerization gi|114520592|ref|NP_001041632.1|/0/microtubule-associated protein 6 isoform 2 [Mus musculus] 18294 1556 3.6 3.77 0.066567617 Up 0.143235925 Ogg1 8-oxoguanine DNA-glycosylase 1 K03660|1|0.0|717|mmu:18294|N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] GO:0034399//nuclear periphery;GO:0016604//nuclear body GO:0008534//oxidized purine nucleobase lesion DNA N-glycosylase activity;GO:0003677//DNA binding;GO:0015631//tubulin binding;GO:0004518//nuclease activity "GO:0006351//transcription, DNA-templated;GO:0043627//response to estrogen;GO:0006285//base-excision repair, AP site formation;GO:0000060//protein import into nucleus, translocation;GO:0009628//response to abiotic stimulus;GO:0006954//inflammatory response;GO:0046686//response to cadmium ion;GO:0097305//response to alcohol" gi|187960092|ref|NP_035087.3|/0/N-glycosylase/DNA lyase [Mus musculus] 13602 3132 150.7433333 147.4333333 -0.032031458 Down 0.143170108 Sparcl1 SPARC-like 1 "K12819|1|1e-10|72.0|dvi:Dvir_GJ26298|pre-mRNA-processing factor SLU7;K08136|2|9e-10|68.9|cfa:482676|sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican)" GO:0044421;GO:0031012//extracellular matrix GO:0046872//metal ion binding GO:0007154//cell communication gi|74145004|dbj|BAE22205.1|/0/unnamed protein product [Mus musculus] 320951 2150 16.60333333 16.18666667 -0.036666989 Down 0.143132498 Pisd phosphatidylserine decarboxylase K01613|1|0.0|844|mmu:320951|phosphatidylserine decarboxylase [EC:4.1.1.65] GO:0043231//intracellular membrane-bounded organelle GO:0016830//carbon-carbon lyase activity GO:0006644//phospholipid metabolic process "gi|126722757|ref|NP_796272.2|/0/phosphatidylserine decarboxylase proenzyme, mitochondrial [Mus musculus]" 12628 4365 15.95 16.37 0.037497898 Up 0.143132498 Cfh complement component factor h K04004|1|0.0|2693|mmu:12628|complement factor H GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0044421 GO:0043168//anion binding;GO:0005539//glycosaminoglycan binding GO:0006956//complement activation;GO:0002673//regulation of acute inflammatory response;GO:0034341//response to interferon-gamma;GO:0032496//response to lipopolysaccharide gi|109627652|ref|NP_034018.2|/0/complement factor H precursor [Mus musculus] 69150 2442 15.30666667 15.72666667 0.039052777 Up 0.143132498 Snx4 sorting nexin 4 K17919|1|0.0|808|mmu:69150|sorting nexin-4 GO:0005769//early endosome;GO:0030286//dynein complex GO:0005543//phospholipid binding GO:0044763;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport gi|18017596|ref|NP_542124.1|/0/sorting nexin-4 [Mus musculus] 102247 3944 16.4 16.82333333 0.036767771 Up 0.143132498 Gpat4 glycerol-3-phosphate acyltransferase 4 K13506|1|0.0|850|mmu:102247|glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15] GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0008374//O-acyltransferase activity GO:0006644//phospholipid metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0006641//triglyceride metabolic process;GO:0035264//multicellular organism growth;GO:0048732//gland development;GO:0007589//body fluid secretion;GO:0006732;GO:0046165 gi|30520301|ref|NP_061213.2|/0/glycerol-3-phosphate acyltransferase 6 precursor [Mus musculus] 217333 2193.26 15.11666667 14.69666667 -0.040651074 Down 0.143132498 Trim47 tripartite motif-containing 47 K12023|1|0.0|1100|mmu:217333|tripartite motif-containing protein 47 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - gi|326537320|ref|NP_766158.3|/0/tripartite motif-containing protein 47 isoform 2 [Mus musculus] 21681 1132 14.42 14.83666667 0.041095835 Up 0.143132498 Alyref Aly/REF export factor K12881|1|2e-65|251|mmu:21681|THO complex subunit 4 GO:0032991//macromolecular complex;GO:0044428//nuclear part GO:0043566//structure-specific DNA binding GO:0009987//cellular process;GO:0051028//mRNA transport gi|6755763|ref|NP_035698.1|/1.66325e-64/THO complex subunit 4 [Mus musculus] 69716 2267 0.26 0.203333333 -0.354664881 Down 0.143076084 Trip13 thyroid hormone receptor interactor 13 K12196|1|2e-14|83.6|loa:LOAG_08200|vacuolar protein-sorting-associated protein 4;K13525|2|2e-12|77.4|loa:LOAG_12115|transitional endoplasmic reticulum ATPase;K14575|4|4e-12|76.3|aec:105143104|AAA family ATPase GO:0043073//germ cell nucleus "GO:0000989//transcription factor activity, transcription factor binding;GO:0032550;GO:0005515//protein binding;GO:0016462//pyrophosphatase activity" "GO:0006281//DNA repair;GO:0007292//female gamete generation;GO:0007129//synapsis;GO:0048232//male gamete generation;GO:0007281//germ cell development;GO:0006351//transcription, DNA-templated;GO:0007128//meiotic prophase I" gi|110625724|ref|NP_081458.1|/0/pachytene checkpoint protein 2 homolog [Mus musculus] 665180 1445 0.276666667 0.216666667 -0.352671618 Down 0.143076084 Clec2l "C-type lectin domain family 2, member L" K06502|1|8e-23|110|asn:102374680|CD69 antigen;K10072|2|2e-22|109|pss:102463843|C-type lectin domain family 2 member D GO:0031224//intrinsic component of membrane GO:0005488//binding - gi|168229210|ref|NP_001094977.1|/1.91435e-98/C-type lectin domain family 2 member L [Mus musculus] 11811 1218 145.7266667 142.54 -0.031898072 Down 0.143066682 Apobec2 "apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2" K18772|1|9e-110|399|mmu:11811|C->U-editing enzyme APOBEC2 [EC:3.5.4.-] - "GO:0003676//nucleic acid binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0046914//transition metal ion binding" GO:0009451//RNA modification;GO:0035510;GO:0006396//RNA processing;GO:0006216//cytidine catabolic process gi|6753098|ref|NP_033824.1|/7.17506e-109/C->U-editing enzyme APOBEC-2 [Mus musculus] 381310 6557 0.456666667 0.383333333 -0.252542032 Down 0.143057279 6330403A02Rik mechanosensory transduction mediator - GO:0031224//intrinsic component of membrane - - "gi|148681206|gb|EDL13153.1|/4.41278e-78/mCG6213, partial [Mus musculus]" 268970 5317 0.376666667 0.446666667 0.245910228 Up 0.143057279 Arhgap28 Rho GTPase activating protein 28 K08878|1|8e-17|93.2|bacu:102998788|breakpoint cluster region protein [EC:2.7.11.1] GO:0044464 GO:0008047//enzyme activator activity GO:0007154//cell communication gi|226342973|ref|NP_766552.3|/0/rho GTPase-activating protein 28 [Mus musculus] 319901 5763 0.466666667 0.393333333 -0.246639968 Down 0.143057279 Dsel dermatan sulfate epimerase-like K01794|1|0.0|671|cmk:103182570|chondroitin-glucuronate 5-epimerase [EC:5.1.3.19] GO:0031224//intrinsic component of membrane "GO:0016782//transferase activity, transferring sulfur-containing groups" - gi|124486781|ref|NP_001074785.1|/0/dermatan-sulfate epimerase-like protein precursor [Mus musculus] 23945 3665.42 136.15 139.26 0.032583946 Up 0.143029072 Mgll monoglyceride lipase K01054|1|1e-169|600|mmu:23945|acylglycerol lipase [EC:3.1.1.23] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0016298//lipase activity;GO:0042802//identical protein binding;GO:0016298//lipase activity;GO:0042802//identical protein binding;GO:0016298//lipase activity;GO:0042802//identical protein binding GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0006954//inflammatory response;GO:0006641//triglyceride metabolic process;GO:0019233//sensory perception of pain;GO:0048167//regulation of synaptic plasticity;GO:0001676//long-chain fatty acid metabolic process;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0006954//inflammatory response;GO:0006641//triglyceride metabolic process;GO:0019233//sensory perception of pain;GO:0048167//regulation of synaptic plasticity;GO:0001676//long-chain fatty acid metabolic process;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0006954//inflammatory response;GO:0006641//triglyceride metabolic process;GO:0019233//sensory perception of pain;GO:0048167//regulation of synaptic plasticity;GO:0001676//long-chain fatty acid metabolic process "gi|148666837|gb|EDK99253.1|/0/monoglyceride lipase, isoform CRA_a, partial [Mus musculus]" 66105 2619 137.0333333 140.06 0.031518121 Up 0.142944451 Ube2d3 ubiquitin-conjugating enzyme E2D 3 K06689|1|2e-83|313|amj:102558580|ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23] GO:0031981//nuclear lumen;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part GO:0032550;GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0012501//programmed cell death;GO:0001818//negative regulation of cytokine production;GO:0006259//DNA metabolic process;GO:0043618//regulation of transcription from RNA polymerase II promoter in response to stress;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0001666//response to hypoxia;GO:0006952//defense response "gi|295789408|pdb|3L1Z|A/1.07602e-82/Chain A, Crystal Structure Of The U-Box Domain Of Human E4b Ubiquitin Ligase In Complex With Ubch5c E2 Ubiquitin Conjugating Enzyme" 70957 800 0.073333333 0.12 0.710493383 Up 0.142897439 Stamos "signal transducing adaptor molecule (SH3 domain and ITAM motif) 1, opposite strand" - - - - - 16510 7188 0.126666667 0.076666667 -0.724365557 Down 0.142897439 Kcnh1 "potassium voltage-gated channel, subfamily H (eag-related), member 1" K04904|1|0.0|1875|mmu:16510|potassium voltage-gated channel Eag-related subfamily H member 1 GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0005887//integral component of plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane GO:0004673//protein histidine kinase activity;GO:0005515//protein binding;GO:0060089;GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0004673//protein histidine kinase activity;GO:0005515//protein binding;GO:0060089 "GO:0006351//transcription, DNA-templated;GO:0007267//cell-cell signaling;GO:0030001//metal ion transport;GO:0000768//syncytium formation by plasma membrane fusion;GO:0007165//signal transduction;GO:0006464//cellular protein modification process;GO:0034220//ion transmembrane transport;GO:0006351//transcription, DNA-templated;GO:0030001//metal ion transport;GO:0007165//signal transduction;GO:0006464//cellular protein modification process;GO:0034220//ion transmembrane transport" gi|6754422|ref|NP_034730.1|/0/potassium voltage-gated channel subfamily H member 1 isoform 1 [Mus musculus] 654805 3540 0.08 0.13 0.700439718 Up 0.142897439 F930015N05Rik RIKEN cDNA F930015N05 gene K07809|1|1e-59|234|ssc:100625836|[heparan sulfate]-glucosamine 3-sulfotransferase 3 [EC:2.8.2.30] - - - gi|148678448|gb|EDL10395.1|/2.94987e-86/mCG147344 [Mus musculus] 100043682 2628 0.12 0.073333333 -0.710493383 Down 0.142897439 Gm10584 predicted gene 10584 - - - - gi|74206243|dbj|BAE24882.1|/1.6786e-59/unnamed protein product [Mus musculus] 18481 8197 0.12 0.073333333 -0.710493383 Down 0.142897439 Pak3 p21 protein (Cdc42/Rac)-activated kinase 3 K05733|1|0.0|1035|rno:29433|p21-activated kinase 3 [EC:2.7.11.1] GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0032550;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0017016//Ras GTPase binding;GO:0019904//protein domain specific binding;GO:0043169//cation binding;GO:0032550;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0017016//Ras GTPase binding;GO:0019904//protein domain specific binding;GO:0043169//cation binding;GO:0032550;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0017016//Ras GTPase binding;GO:0019904//protein domain specific binding;GO:0043169//cation binding;GO:0032550;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0017016//Ras GTPase binding;GO:0019904//protein domain specific binding;GO:0043169//cation binding;GO:0032550;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0017016//Ras GTPase binding;GO:0019904//protein domain specific binding;GO:0043169//cation binding GO:0048812//neuron projection morphogenesis;GO:0008064//regulation of actin polymerization or depolymerization;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006468//protein phosphorylation;GO:0048812//neuron projection morphogenesis;GO:0008064//regulation of actin polymerization or depolymerization;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006468//protein phosphorylation;GO:0031175//neuron projection development;GO:0008064//regulation of actin polymerization or depolymerization;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006468//protein phosphorylation;GO:0031175//neuron projection development;GO:0008064//regulation of actin polymerization or depolymerization;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0031175//neuron projection development;GO:0008064//regulation of actin polymerization or depolymerization;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction gi|117606272|ref|NP_032804.2|/0/serine/threonine-protein kinase PAK 3 isoform D [Mus musculus] 58875 1748 149.87 152.7766667 0.027712597 Up 0.142888036 Hibadh 3-hydroxyisobutyrate dehydrogenase K00020|1|0.0|641|mmu:58875|3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] GO:0044429 "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0048037//cofactor binding" GO:0006007//glucose catabolic process;GO:0006573//valine metabolic process;GO:0009063//cellular amino acid catabolic process gi|26347027|dbj|BAC37162.1|/0/unnamed protein product [Mus musculus] 330850 3565 0.856666667 0.766666667 -0.160134498 Down 0.14282222 Gm38416 "predicted gene, 38416" - - - - - 71846 911 0.743333333 0.83 0.159102032 Up 0.14282222 Syce2 synaptonemal complex central element protein 2 K19535|1|2e-38|161|mmu:71846|synaptonemal complex central element protein 2 GO:0000795//synaptonemal complex;GO:0000795//synaptonemal complex GO:0005488//binding;GO:0005488//binding GO:0007129//synapsis;GO:0007129//synapsis gi|270133328|ref|NP_082230.2|/2.64422e-93/synaptonemal complex central element protein 2 isoform 2 [Mus musculus] 94212 8197 0.786666667 0.876666667 0.15627594 Up 0.14282222 Pag1 phosphoprotein associated with glycosphingolipid microdomains 1 - GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding GO:0042110//T cell activation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0042110//T cell activation;GO:0007167//enzyme linked receptor protein signaling pathway "gi|148673233|gb|EDL05180.1|/0/phosphoprotein associated with glycosphingolipid microdomains 1, isoform CRA_b, partial [Mus musculus]" 72514 1775 0.78 0.873333333 0.163058282 Up 0.14282222 Fgfbp3 fibroblast growth factor binding protein 3 - - GO:0005539//glycosaminoglycan binding;GO:0019838//growth factor binding GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0043114//regulation of vascular permeability gi|139948267|ref|NP_082539.2|/1.9996e-87/fibroblast growth factor-binding protein 3 precursor [Mus musculus] 16661 2124 0.743333333 0.83 0.159102032 Up 0.14282222 Krt10 keratin 10 "K07604|1|1e-160|569|mmu:16661|type I keratin, acidic" GO:0005882//intermediate filament - GO:0051592//response to calcium ion;GO:0009913//epidermal cell differentiation "gi|755537500|ref|XP_011247070.1|/8.41648e-160/PREDICTED: keratin, type I cytoskeletal 10 isoform X1 [Mus musculus]" 65962 1912.58 119.3166667 116.51 -0.034341793 Down 0.14278461 Slc9a3r2 "solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2" K13358|1|1e-180|635|mmu:65962|Na(+)/H(+) exchange regulatory cofactor NHE-RF2 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459 GO:0070325//lipoprotein particle receptor binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0070325//lipoprotein particle receptor binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding GO:0009968//negative regulation of signal transduction;GO:0042391//regulation of membrane potential;GO:0009968//negative regulation of signal transduction;GO:0043583//ear development;GO:0042391//regulation of membrane potential gi|226246650|ref|NP_075938.2|/4.14582e-119/Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform B [Mus musculus] 320007 4266 0.086666667 0.14 0.691877705 Up 0.142690586 Sidt1 "SID1 transmembrane family, member 1" - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0051032;GO:0051032 GO:0044765//single-organism transport;GO:0035194//posttranscriptional gene silencing by RNA;GO:0044765//single-organism transport;GO:0035194//posttranscriptional gene silencing by RNA gi|226874931|ref|NP_001152891.1|/0/SID1 transmembrane family member 1 isoform 1 precursor [Mus musculus] 69306 767 0.076666667 0.123333333 0.68589141 Up 0.142690586 Efcab9 EF-hand calcium binding domain 9 - - GO:0046872//metal ion binding - gi|238550131|ref|NP_081307.2|/1.14948e-106/EF-hand calcium-binding domain-containing protein 9 [Mus musculus] 269356 3201 0.14 0.086666667 -0.691877705 Down 0.142690586 Slc4a11 "solute carrier family 4, sodium bicarbonate transporter-like, member 11" "K13862|1|0.0|1568|mmu:269356|solute carrier family 4 (sodium borate transporter), member 11" GO:0031224//intrinsic component of membrane GO:0015103//inorganic anion transmembrane transporter activity;GO:0005402//cation:sugar symporter activity;GO:0005515//protein binding;GO:0005261//cation channel activity;GO:0015301//anion:anion antiporter activity GO:0006814//sodium ion transport;GO:0006818//hydrogen transport;GO:0015711//organic anion transport;GO:0006873//cellular ion homeostasis;GO:0008643//carbohydrate transport;GO:0034220//ion transmembrane transport gi|124487207|ref|NP_001074631.1|/0/sodium bicarbonate transporter-like protein 11 [Mus musculus] 20897 2784 0.086666667 0.14 0.691877705 Up 0.142690586 Stra6 stimulated by retinoic acid gene 6 - GO:0032991//macromolecular complex;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0031224//intrinsic component of membrane GO:0005215//transporter activity;GO:0005215//transporter activity;GO:0005215//transporter activity;GO:0005215//transporter activity GO:0001523//retinoid metabolic process;GO:0060538//skeletal muscle organ development;GO:0048844//artery morphogenesis;GO:0040007//growth;GO:0035461//vitamin transmembrane transport;GO:0043010//camera-type eye development;GO:0060428//lung epithelium development;GO:0007612//learning;GO:0003177;GO:0060537//muscle tissue development;GO:0009887//organ morphogenesis;GO:0048565//digestive tract development;GO:0046545//development of primary female sexual characteristics;GO:0035270//endocrine system development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0003231//cardiac ventricle development;GO:0001523//retinoid metabolic process;GO:0060538//skeletal muscle organ development;GO:0048844//artery morphogenesis;GO:0040007//growth;GO:0035461//vitamin transmembrane transport;GO:0043010//camera-type eye development;GO:0060428//lung epithelium development;GO:0007612//learning;GO:0003177;GO:0060537//muscle tissue development;GO:0009887//organ morphogenesis;GO:0048565//digestive tract development;GO:0046545//development of primary female sexual characteristics;GO:0035270//endocrine system development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0003231//cardiac ventricle development;GO:0001523//retinoid metabolic process;GO:0060538//skeletal muscle organ development;GO:0048844//artery morphogenesis;GO:0040007//growth;GO:0035461//vitamin transmembrane transport;GO:0043010//camera-type eye development;GO:0060428//lung epithelium development;GO:0007612//learning;GO:0003177;GO:0060537//muscle tissue development;GO:0009887//organ morphogenesis;GO:0048565//digestive tract development;GO:0046545//development of primary female sexual characteristics;GO:0035270//endocrine system development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0003231//cardiac ventricle development;GO:0001523//retinoid metabolic process;GO:0060538//skeletal muscle organ development;GO:0048844//artery morphogenesis;GO:0040007//growth;GO:0035461//vitamin transmembrane transport;GO:0043010//camera-type eye development;GO:0060428//lung epithelium development;GO:0007612//learning;GO:0003177;GO:0060537//muscle tissue development;GO:0009887//organ morphogenesis;GO:0048565//digestive tract development;GO:0046545//development of primary female sexual characteristics;GO:0035270//endocrine system development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0003231//cardiac ventricle development gi|242332597|ref|NP_033317.2|/0/stimulated by retinoic acid gene 6 protein [Mus musculus] 100502619 1498 0.076666667 0.123333333 0.68589141 Up 0.142690586 AW046200 expressed sequence AW046200 - - - - - 17996 22489 0.123333333 0.076666667 -0.68589141 Down 0.142690586 Neb nebulin K18267|1|0.0|1.416e+04|mmu:17996|nebulin - - - gi|148222065|ref|NP_035019.1|/0/nebulin [Mus musculus] 13476 2910 123.21 125.92 0.031388093 Up 0.142690586 Reep5 receptor accessory protein 5 K17279|1|6e-93|345|mmu:13476|receptor expression-enhancing protein 5/6 GO:0031224//intrinsic component of membrane - - gi|161016826|ref|NP_031900.3|/4.91841e-92/receptor expression-enhancing protein 5 [Mus musculus] 381680 2312 0.133333333 0.083333333 -0.678071905 Down 0.142690586 Nxpe5 "neurexophilin and PC-esterase domain family, member 5" "K15010|1|3e-29|132|xma:102227992|homer;K02324|2|2e-25|120|sko:100367259|DNA polymerase epsilon subunit 1 [EC:2.7.7.7];K07422|3|2e-13|80.5|bfo:BRAFLDRAFT_72966|cytochrome P450, family 2, subfamily U, polypeptide 1" - - - gi|157841165|ref|NP_001013795.3|/0/uncharacterized protein LOC381680 [Mus musculus] 54152 1492 15.41666667 15.82333333 0.037562684 Up 0.142681184 Dnal4 "dynein, axonemal, light chain 4" "K10412|1|9e-56|220|tup:102498653|dynein light chain 4, axonemal" GO:0030286//dynein complex;GO:0016020//membrane;GO:0005930//axoneme GO:0003774//motor activity;GO:0016887//ATPase activity GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006928//movement of cell or subcellular component "gi|168693651|ref|NP_059498.2|/7.97951e-55/dynein light chain 4, axonemal [Mus musculus]" 74126 3229.37 15.06666667 15.47333333 0.03842375 Up 0.142681184 Syvn1 "synovial apoptosis inhibitor 1, synoviolin" K10601|1|0.0|679|rno:361712|E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0046914//transition metal ion binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0046914//transition metal ion binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds" GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0043009//chordate embryonic development;GO:0006487//protein N-linked glycosylation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0043009//chordate embryonic development;GO:0006487//protein N-linked glycosylation "gi|149062129|gb|EDM12552.1|/0/synovial apoptosis inhibitor 1, synoviolin, isoform CRA_b [Rattus norvegicus]" 74302 5691 15.34333333 14.93666667 -0.038753716 Down 0.142681184 Mtmr3 myotubularin related protein 3 K18082|1|0.0|2264|mmu:74302|myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95] GO:0031981//nuclear lumen GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity;GO:0052744//phosphatidylinositol monophosphate phosphatase activity GO:0046488//phosphatidylinositol metabolic process;GO:0006470//protein dephosphorylation gi|145207976|ref|NP_083136.2|/0/myotubularin-related protein 3 [Mus musculus] 22682 7385 13.58666667 13.99666667 0.042891737 Up 0.142681184 Zfand5 "zinc finger, AN1-type domain 5" K14785|1|3e-14|85.1|dpo:Dpse_GA17094|ESF2/ABP1 family protein;K12163|2|2e-12|79.3|dre:100148477|AN1-type zinc finger and ubiquitin domain-containing protein 1 GO:0044424 GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding GO:0003008;GO:0001501//skeletal system development;GO:0060537//muscle tissue development;GO:0044767//single-organism developmental process;GO:0001667//ameboidal-type cell migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway "gi|148709637|gb|EDL41583.1|/4.07321e-104/zinc finger, AN1-type domain 5, partial [Mus musculus]" 207304 8988 13.52 13.10666667 -0.044794331 Down 0.142681184 Hectd1 HECT domain containing 1 K12231|1|0.0|4540|mmu:207304|E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26] GO:0044464 GO:0043169//cation binding;GO:0019787//ubiquitin-like protein transferase activity GO:0022610 gi|205277432|ref|NP_659037.2|/0/E3 ubiquitin-protein ligase HECTD1 [Mus musculus] 331026 1789 15.40333333 14.99666667 -0.038600723 Down 0.142681184 Gmppb GDP-mannose pyrophosphorylase B K00966|1|0.0|726|mmu:331026|mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0008905//mannose-phosphate guanylyltransferase activity GO:0009226//nucleotide-sugar biosynthetic process;GO:0006487//protein N-linked glycosylation gi|564365550|ref|XP_006243873.1|/0/PREDICTED: mannose-1-phosphate guanyltransferase beta isoform X1 [Rattus norvegicus] 17283 2747.7 16.05333333 16.46666667 0.03667565 Up 0.142681184 Men1 multiple endocrine neoplasia 1 K14970|1|0.0|967|mmu:17283|menin GO:0034399//nuclear periphery;GO:0032155;GO:0034708;GO:0044444//cytoplasmic part;GO:0044427;GO:0034399//nuclear periphery;GO:0032155;GO:0034708;GO:0044444//cytoplasmic part;GO:0044427;GO:0034399//nuclear periphery;GO:0032155;GO:0034708;GO:0044444//cytoplasmic part;GO:0044427;GO:0034399//nuclear periphery;GO:0032155;GO:0034708;GO:0044444//cytoplasmic part;GO:0044427 GO:0000975//regulatory region DNA binding;GO:0000217//DNA secondary structure binding;GO:0046332//SMAD binding;GO:0000975//regulatory region DNA binding;GO:0000217//DNA secondary structure binding;GO:0046332//SMAD binding;GO:0000975//regulatory region DNA binding;GO:0000217//DNA secondary structure binding;GO:0046332//SMAD binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0000975//regulatory region DNA binding;GO:0000217//DNA secondary structure binding;GO:0046332//SMAD binding GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016571//histone methylation;GO:0035265//organ growth;GO:0006915//apoptotic process;GO:0048534//hematopoietic or lymphoid organ development;GO:0048562//embryonic organ morphogenesis;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0032924//activin receptor signaling pathway;GO:0022402//cell cycle process;GO:0009416//response to light stimulus;GO:0007254//JNK cascade;GO:0001649//osteoblast differentiation;GO:0010212//response to ionizing radiation;GO:0043393//regulation of protein binding;GO:0051348//negative regulation of transferase activity;GO:0048522;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007565//female pregnancy;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016571//histone methylation;GO:0035265//organ growth;GO:0006915//apoptotic process;GO:0048534//hematopoietic or lymphoid organ development;GO:0048562//embryonic organ morphogenesis;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0032924//activin receptor signaling pathway;GO:0022402//cell cycle process;GO:0009416//response to light stimulus;GO:0007254//JNK cascade;GO:0001649//osteoblast differentiation;GO:0010212//response to ionizing radiation;GO:0043393//regulation of protein binding;GO:0051348//negative regulation of transferase activity;GO:0048522;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007565//female pregnancy;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016571//histone methylation;GO:0035265//organ growth;GO:0006915//apoptotic process;GO:0048534//hematopoietic or lymphoid organ development;GO:0048562//embryonic organ morphogenesis;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0032924//activin receptor signaling pathway;GO:0022402//cell cycle process;GO:0009416//response to light stimulus;GO:0007254//JNK cascade;GO:0001649//osteoblast differentiation;GO:0010212//response to ionizing radiation;GO:0043393//regulation of protein binding;GO:0051348//negative regulation of transferase activity;GO:0048522;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007565//female pregnancy;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016571//histone methylation;GO:0035265//organ growth;GO:0006915//apoptotic process;GO:0048534//hematopoietic or lymphoid organ development;GO:0048562//embryonic organ morphogenesis;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0032924//activin receptor signaling pathway;GO:0022402//cell cycle process;GO:0009416//response to light stimulus;GO:0007254//JNK cascade;GO:0001649//osteoblast differentiation;GO:0010212//response to ionizing radiation;GO:0043393//regulation of protein binding;GO:0051348//negative regulation of transferase activity;GO:0048522;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007565//female pregnancy gi|270309147|ref|NP_001161960.1|/0/menin isoform a [Mus musculus] 69790 871 7.603333333 7.863333333 0.048508972 Up 0.142615367 Med30 mediator complex subunit 30 K15143|1|5e-90|333|mmu:69790|mediator of RNA polymerase II transcription subunit 30 GO:0043234//protein complex;GO:0031981//nuclear lumen "GO:0008134//transcription factor binding;GO:0003713//transcription coactivator activity;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter gi|19882231|ref|NP_081488.1|/3.64391e-89/mediator of RNA polymerase II transcription subunit 30 [Mus musculus] 67623 3312 7.39 7.65 0.049885383 Up 0.142615367 Tm7sf3 transmembrane 7 superfamily member 3 - GO:0031224//intrinsic component of membrane - - gi|12846367|dbj|BAB27141.1|/0/unnamed protein product [Mus musculus] 27377 4571 8.366666667 8.106666667 -0.045544135 Down 0.142615367 Yme1l1 YME1-like 1 (S. cerevisiae) K08955|1|0.0|1406|mmu:27377|ATP-dependent metalloprotease [EC:3.4.24.-] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0043169//cation binding;GO:0032550;GO:0004175//endopeptidase activity;GO:0016462//pyrophosphatase activity GO:0006996//organelle organization;GO:0051603//proteolysis involved in cellular protein catabolic process gi|7305635|ref|NP_038799.1|/0/ATP-dependent zinc metalloprotease YME1L1 [Mus musculus] 226751 8656 6.793333333 7.053333333 0.054185576 Up 0.142615367 Cdc42bpa CDC42 binding protein kinase alpha K16307|1|0.0|3248|mmu:226751|serine/threonine-protein kinase MRCK [EC:2.7.11.1] GO:0030054//cell junction;GO:0015629//actin cytoskeleton GO:0032550;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0008289//lipid binding;GO:0005515//protein binding GO:0040023//establishment of nucleus localization;GO:0048870//cell motility;GO:0007264//small GTPase mediated signal transduction;GO:0006464//cellular protein modification process;GO:0030036//actin cytoskeleton organization;GO:0006796//phosphate-containing compound metabolic process gi|254692972|ref|NP_001028457.1|/0/serine/threonine-protein kinase MRCK alpha [Mus musculus] 70040 3631 0.216666667 0.273333333 0.335184192 Up 0.14258716 2610037D02Rik RIKEN cDNA 2610037D02 gene - - - - - 319224 3869 0.236666667 0.3 0.342105977 Up 0.14258716 6330410L21Rik RIKEN cDNA 6330410L21 gene K04257|1|5e-16|57.8|hgl:106008731|olfactory receptor;K04357|3|1e-15|89.0|mmu:13645|epidermal growth factor - - - - 12772 3589 0.213333333 0.27 0.339850003 Up 0.14258716 Ccr2 chemokine (C-C motif) receptor 2 K04177|1|0.0|689|mmu:12772|C-C chemokine receptor type 2 GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0044444//cytoplasmic part;GO:0043025//neuronal cell body GO:0019957//C-C chemokine binding;GO:0048020//CCR chemokine receptor binding;GO:0042802//identical protein binding;GO:0004950//chemokine receptor activity GO:0006954//inflammatory response;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0002699//positive regulation of immune effector process;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0035697;GO:0002695//negative regulation of leukocyte activation;GO:0019221//cytokine-mediated signaling pathway;GO:0007600//sensory perception;GO:0048771//tissue remodeling;GO:0001819//positive regulation of cytokine production;GO:0045063//T-helper 1 cell differentiation;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0035704;GO:0001525//angiogenesis;GO:0002824;GO:0002828//regulation of type 2 immune response;GO:0002693//positive regulation of cellular extravasation;GO:0000165//MAPK cascade;GO:0006909//phagocytosis;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0042102//positive regulation of T cell proliferation gi|6753466|ref|NP_034045.1|/0/C-C chemokine receptor type 2 [Mus musculus] 56066 1597 0.633333333 0.556666667 -0.186151316 Down 0.142558953 Cxcl11 chemokine (C-X-C motif) ligand 11 K12672|1|3e-43|178|mmu:56066|C-X-C motif chemokine 11 GO:0044421;GO:0044421 GO:0001664//G-protein coupled receptor binding;GO:0005125//cytokine activity;GO:0001664//G-protein coupled receptor binding;GO:0005125//cytokine activity GO:0006952//defense response;GO:0002376//immune system process;GO:0042221//response to chemical;GO:0006952//defense response;GO:0002376//immune system process;GO:0042221//response to chemical gi|9507071|ref|NP_062367.1|/1.59815e-40/C-X-C motif chemokine 11 precursor [Mus musculus] 77127 1366 0.633333333 0.553333333 -0.194816177 Down 0.142558953 A930001A20Rik RIKEN cDNA A930001A20 gene K11426|1|2e-08|63.2|cfa:480026|SET and MYND domain-containing protein - - - - 12722 3899 0.626666667 0.55 -0.188266637 Down 0.142558953 Clca3a1 chloride channel accessory 3A1 K05030|1|0.0|501|pss:102456534|calcium-activated chloride channel regulator 4;K05027|3|0.0|538|fca:101101241|calcium-activated chloride channel regulator 1 GO:0016021//integral component of membrane;GO:0016020//membrane GO:0005216//ion channel activity;GO:0005216//ion channel activity GO:0015698//inorganic anion transport;GO:0012501//programmed cell death;GO:0012501//programmed cell death "gi|148680076|gb|EDL12023.1|/0/mCG3350, isoform CRA_c, partial [Mus musculus]" 68095 1596.1 112.4833333 114.9833333 0.031713507 Up 0.142502539 Ociad1 OCIA domain containing 1 K11170|1|1e-06|57.0|bfo:BRAFLDRAFT_90676|dehydrogenase/reductase SDR family member X [EC:1.1.-.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|229577358|ref|NP_001153360.1|/7.01993e-106/OCIA domain-containing protein 1 isoform 3 [Mus musculus] 17961 1375 1.04 1.14 0.132450296 Up 0.142455527 Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) K00622|1|5e-167|589|mmu:17961|arylamine N-acetyltransferase [EC:2.3.1.5] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0008080//N-acetyltransferase activity;GO:0045182//translation regulator activity;GO:0008080//N-acetyltransferase activity;GO:0045182//translation regulator activity GO:0006412//translation;GO:0044767//single-organism developmental process;GO:0014070//response to organic cyclic compound;GO:0006412//translation;GO:0044767//single-organism developmental process;GO:0014070//response to organic cyclic compound gi|568955296|ref|XP_006509655.1|/2.37389e-167/PREDICTED: arylamine N-acetyltransferase 2 isoform X1 [Mus musculus] 269952 3520 1.123333333 1.226666667 0.126957175 Up 0.142455527 Gdpgp1 GDP-D-glucose phosphorylase 1 K15630|1|0.0|780|mmu:269952|GDP-D-glucose phosphorylase [EC:2.7.7.78] - GO:0004645//phosphorylase activity - gi|123702129|ref|NP_848867.2|/0/GDP-D-glucose phosphorylase 1 [Mus musculus] 271849 4820 1.143333333 1.046666667 -0.127444017 Down 0.142455527 Shc4 "SHC (Src homology 2 domain containing) family, member 4" K17449|1|0.0|1241|mmu:271849|SHC-transforming protein 4 - - - gi|39841043|ref|NP_950187.1|/0/SHC-transforming protein 4 [Mus musculus] 317750 1951 1.14 1.04 -0.132450296 Down 0.142455527 Slc24a5 "solute carrier family 24, member 5" "K13753|1|0.0|813|mmu:317750|solute carrier family 24 (sodium/potassium/calcium exchanger), member 5" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0044763;GO:0070838//divalent metal ion transport gi|110681724|ref|NP_778199.2|/0/sodium/potassium/calcium exchanger 5 precursor [Mus musculus] 74998 5316.87 1.063333333 1.163333333 0.129670612 Up 0.142455527 Rab11fip2 RAB11 family interacting protein 2 (class I) K12484|1|0.0|745|mmu:74998|Rab11 family-interacting protein 1/2/5 GO:0012506//vesicle membrane;GO:0010008//endosome membrane;GO:0031981//nuclear lumen;GO:0012506//vesicle membrane;GO:0010008//endosome membrane;GO:0031981//nuclear lumen GO:0042802//identical protein binding;GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0019900//kinase binding GO:0007163//establishment or maintenance of cell polarity;GO:0045184//establishment of protein localization;GO:0042044//fluid transport;GO:0007163//establishment or maintenance of cell polarity;GO:0045184//establishment of protein localization;GO:0042044//fluid transport gi|256773180|ref|NP_001028344.2|/0/rab11 family-interacting protein 2 isoform 1 [Mus musculus] 399568 2752 1.556666667 1.673333333 0.104264814 Up 0.142446124 BC052040 cDNA sequence BC052040 - - - - gi|225543363|ref|NP_001139370.1|/1.84978e-157/uncharacterized protein C15orf41 homolog isoform 1 [Mus musculus] 230787 2542 1.6 1.716666667 0.101538026 Up 0.142446124 Themis2 thymocyte selection associated family member 2 - GO:0043231//intracellular membrane-bounded organelle - GO:0006952//defense response;GO:0050851//antigen receptor-mediated signaling pathway;GO:0022610 "gi|15489209|gb|AAH13712.1|/0/BC013712 protein, partial [Mus musculus]" 109065 3413 1.64 1.756666667 0.099144646 Up 0.142446124 Dnaaf2 "dynein, axonemal assembly factor 2" "K19751|1|0.0|1388|mmu:109065|dynein assembly factor 2, axonemal" - - - - 78605 3689 1.806666667 1.93 0.095270497 Up 0.142446124 6430706D22Rik RIKEN cDNA 6430706D22 gene - GO:0031981//nuclear lumen;GO:0000776//kinetochore GO:0005515//protein binding GO:0006461//protein complex assembly;GO:0043486//histone exchange;GO:0051098//regulation of binding gi|51100802|dbj|BAD36742.1|/0/mfleg1 [Mus musculus] 269060 5652 1.593333333 1.71 0.101948208 Up 0.142446124 Dagla "diacylglycerol lipase, alpha" K13806|1|0.0|1879|mmu:269060|sn1-specific diacylglycerol lipase [EC:3.1.1.-] GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0003824//catalytic activity GO:0042133//neurotransmitter metabolic process;GO:0038171//cannabinoid signaling pathway;GO:0001676//long-chain fatty acid metabolic process;GO:0048699//generation of neurons gi|154091036|ref|NP_932782.2|/0/sn1-specific diacylglycerol lipase alpha [Mus musculus] 66255 1258 1.736666667 1.86 0.09898175 Up 0.142446124 Hsbp1l1 heat shock factor binding protein 1-like 1 K19765|1|4e-14|81.6|hgl:101724263|heat shock factor-binding protein 1 - - - gi|209969762|ref|NP_001129653.1|/1.83421e-22/heat shock factor-binding protein 1-like protein 1 [Mus musculus] 21390 1963 1.693333333 1.576666667 -0.102988313 Down 0.142446124 Tbxa2r thromboxane A2 receptor K04264|1|2e-158|561|mmu:21390|thromboxane A2 receptor GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004954;GO:0004954 GO:0006952//defense response;GO:0001525//angiogenesis;GO:0035556//intracellular signal transduction;GO:0031667//response to nutrient levels;GO:0008217//regulation of blood pressure;GO:0019229//regulation of vasoconstriction;GO:0007166//cell surface receptor signaling pathway;GO:0006939//smooth muscle contraction;GO:0002237//response to molecule of bacterial origin;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0006952//defense response;GO:0001525//angiogenesis;GO:0035556//intracellular signal transduction;GO:0031667//response to nutrient levels;GO:0008217//regulation of blood pressure;GO:0019229//regulation of vasoconstriction;GO:0007166//cell surface receptor signaling pathway;GO:0006939//smooth muscle contraction;GO:0002237//response to molecule of bacterial origin;GO:0051480//regulation of cytosolic calcium ion concentration gi|6678233|ref|NP_033351.1|/2.08374e-157/thromboxane A2 receptor [Mus musculus] 18214 8306 1.8 1.676666667 -0.102401007 Down 0.142446124 Ddr2 "discoidin domain receptor family, member 2" K05125|1|0.0|1665|mmu:18214|discoidin domain receptor family member 2 [EC:2.7.10.1] GO:0031224//intrinsic component of membrane;GO:0044459 GO:0032550;GO:0005515//protein binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity GO:0001934//positive regulation of protein phosphorylation;GO:0060350//endochondral bone morphogenesis;GO:0009888//tissue development;GO:0030278//regulation of ossification;GO:0001649//osteoblast differentiation;GO:0010761//fibroblast migration;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0022610;GO:0008284//positive regulation of cell proliferation;GO:0044093;GO:0010715//regulation of extracellular matrix disassembly gi|158508514|ref|NP_072075.2|/0/discoidin domain-containing receptor 2 precursor [Mus musculus] 102800312 1489 1.72 1.603333333 -0.101334172 Down 0.142446124 Lncppara long noncoding RNA near Ppara - - - - - 74355 7053 1.78 1.663333333 -0.097799926 Down 0.142446124 Smchd1 SMC hinge domain containing 1 - - - - gi|148839318|ref|NP_083163.3|/0/structural maintenance of chromosomes flexible hinge domain-containing protein 1 [Mus musculus] 13806 1831 102.6233333 105.0566667 0.033808923 Up 0.142436722 Eno1 "enolase 1, alpha non-neuron" K01689|1|0.0|858|xla:100037034|enolase [EC:4.2.1.11] - - - - 77889 3068 133.28 135.6366667 0.025286929 Up 0.142361503 Lbh limb-bud and heart K04010|1|8e-08|62.4|tru:101075680|C5a anaphylatoxin chemotactic receptor GO:0031981//nuclear lumen - "GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|672055562|ref|XP_008762755.1|/1.75292e-55/PREDICTED: protein LBH isoform X1 [Rattus norvegicus] 108686 8862 0.48 0.406666667 -0.239187664 Down 0.142342698 Ccdc88a coiled coil domain containing 88A K20478|1|4e-47|194|dre:557772|golgin subfamily B member 1 - - - gi|63025208|ref|NP_789811.2|/0/girdin [Mus musculus] 56405 1443 0.376666667 0.443333333 0.235103473 Up 0.142342698 Dusp14 dual specificity phosphatase 14 K14165|1|8e-113|409|mmu:56405|atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] - - - gi|676278109|gb|KFO32189.1|/1.04246e-112/Dual specificity protein phosphatase 14 [Fukomys damarensis] 13207 3520 97.69 95.44333333 -0.033566459 Down 0.142323893 Ddx5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 K12823|1|0.0|1118|mmu:13207|ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13] GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen "GO:0035258//steroid hormone receptor binding;GO:0003712//transcription cofactor activity;GO:0003724//RNA helicase activity;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003723//RNA binding" "GO:0030520//intracellular estrogen receptor signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0043009//chordate embryonic development;GO:0019079//viral genome replication;GO:0035914//skeletal muscle cell differentiation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0009154//purine ribonucleotide catabolic process;GO:0001649//osteoblast differentiation;GO:0040007//growth;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0048511//rhythmic process;GO:0006366//transcription from RNA polymerase II promoter" gi|74210167|dbj|BAE21355.1|/0/unnamed protein product [Mus musculus] 29813 2320 16.25 15.84666667 -0.036260316 Down 0.142314491 Zfp385a zinc finger protein 385A "K10137|1|9e-09|65.1|gfr:102036629|zinc finger, matrin type 3" GO:0043005//neuron projection;GO:0044297//cell body GO:0003729//mRNA binding;GO:0046914//transition metal ion binding GO:0050878//regulation of body fluid levels;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0002181//cytoplasmic translation;GO:0030219//megakaryocyte differentiation;GO:0008298//intracellular mRNA localization;GO:0044708//single-organism behavior;GO:0033363//secretory granule organization;GO:0045444//fat cell differentiation gi|119360327|ref|NP_038894.2|/2.38837e-171/zinc finger protein 385A [Mus musculus] 68585 5717.34 14.01 14.40666667 0.040279616 Up 0.142314491 Rtn4 reticulon 4 K08288|1|3e-61|239|chx:102186405|protein kinase C substrate 80K-H GO:0032991//macromolecular complex;GO:0044297//cell body;GO:0042995//cell projection;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0032991//macromolecular complex;GO:0044297//cell body;GO:0042995//cell projection;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0032991//macromolecular complex;GO:0044297//cell body;GO:0042995//cell projection;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0032991//macromolecular complex;GO:0044297//cell body;GO:0042995//cell projection;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0032991//macromolecular complex;GO:0044297//cell body;GO:0042995//cell projection;GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0014046;GO:0001837//epithelial to mesenchymal transition;GO:0007029//endoplasmic reticulum organization;GO:0031103//axon regeneration;GO:0021545//cranial nerve development;GO:0030308//negative regulation of cell growth;GO:0021799//cerebral cortex radially oriented cell migration;GO:0010001//glial cell differentiation;GO:0019233//sensory perception of pain;GO:0010977//negative regulation of neuron projection development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0014046;GO:0006915//apoptotic process;GO:0007029//endoplasmic reticulum organization;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0031103//axon regeneration;GO:0021545//cranial nerve development;GO:0030308//negative regulation of cell growth;GO:0021799//cerebral cortex radially oriented cell migration;GO:0010001//glial cell differentiation;GO:0019233//sensory perception of pain;GO:0010977//negative regulation of neuron projection development;GO:0014046;GO:0006915//apoptotic process;GO:0007029//endoplasmic reticulum organization;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0031103//axon regeneration;GO:0021545//cranial nerve development;GO:0030308//negative regulation of cell growth;GO:0021799//cerebral cortex radially oriented cell migration;GO:0010001//glial cell differentiation;GO:0019233//sensory perception of pain;GO:0010977//negative regulation of neuron projection development;GO:0014046;GO:0001837//epithelial to mesenchymal transition;GO:0007029//endoplasmic reticulum organization;GO:0031103//axon regeneration;GO:0021545//cranial nerve development;GO:0030308//negative regulation of cell growth;GO:0021799//cerebral cortex radially oriented cell migration;GO:0010001//glial cell differentiation;GO:0019233//sensory perception of pain;GO:0010977//negative regulation of neuron projection development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0014046;GO:0001837//epithelial to mesenchymal transition;GO:0006915//apoptotic process;GO:0007029//endoplasmic reticulum organization;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0031103//axon regeneration;GO:0021545//cranial nerve development;GO:0030308//negative regulation of cell growth;GO:0021799//cerebral cortex radially oriented cell migration;GO:0010001//glial cell differentiation;GO:0019233//sensory perception of pain;GO:0010977//negative regulation of neuron projection development gi|34610237|ref|NP_918940.1|/0/reticulon-4 isoform D [Mus musculus] 74319 1055 15.16666667 15.56333333 0.037247043 Up 0.142314491 Mettl23 methyltransferase like 23 K00884|1|1e-12|76.3|cbr:CBG13487|N-acetylglucosamine kinase [EC:2.7.1.59] GO:0031224//intrinsic component of membrane GO:0016741 GO:0008152//metabolic process gi|148702653|gb|EDL34600.1|/9.34161e-152/mCG141687 [Mus musculus] 224093 3075 13.97666667 14.37666667 0.040708886 Up 0.142314491 Fam43a "family with sequence similarity 43, member A" K14539|1|3e-35|153|cmk:103184473|large subunit GTPase 1 [EC:3.6.1.-];K12474|2|2e-10|70.9|sko:102804161|low density lipoprotein receptor adapter protein 1 - - - gi|29244026|ref|NP_808300.1|/0/protein FAM43A [Mus musculus] 20255 2192 0.093333333 0.146666667 0.652076697 Up 0.142295686 Scg3 secretogranin III K18406|1|2e-09|67.4|cge:100751975|tudor domain-containing protein 2 GO:0030133//transport vesicle;GO:0030133//transport vesicle - - "gi|148694386|gb|EDL26333.1|/0/secretogranin III, isoform CRA_a, partial [Mus musculus]" 14634 8428 0.136666667 0.086666667 -0.657112286 Down 0.142295686 Gli3 GLI-Kruppel family member GLI3 K06230|1|0.0|2775|mmu:14634|zinc finger protein GLI3 GO:0043234//protein complex;GO:0016604//nuclear body;GO:0005929//cilium;GO:0044444//cytoplasmic part GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0019899//enzyme binding GO:0030326//embryonic limb morphogenesis;GO:0007224//smoothened signaling pathway;GO:0010092//specification of organ identity;GO:0021520//spinal cord motor neuron cell fate specification;GO:0021521//ventral spinal cord interneuron specification;GO:0048732//gland development;GO:0048562//embryonic organ morphogenesis;GO:0048754//branching morphogenesis of an epithelial tube;GO:0043383//negative T cell selection;GO:0007405//neuroblast proliferation;GO:0043009//chordate embryonic development;GO:0002062//chondrocyte differentiation;GO:0070231//T cell apoptotic process;GO:0048546//digestive tract morphogenesis;GO:0050931//pigment cell differentiation;GO:0001822//kidney development;GO:0042476//odontogenesis;GO:0001649//osteoblast differentiation;GO:0040007//growth;GO:0060363//cranial suture morphogenesis;GO:0006935//chemotaxis;GO:0021872//forebrain generation of neurons;GO:0045582//positive regulation of T cell differentiation;GO:0060872//semicircular canal development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0006606//protein import into nucleus;GO:0045581//negative regulation of T cell differentiation;GO:0043010//camera-type eye development;GO:0048545//response to steroid hormone;GO:0006366//transcription from RNA polymerase II promoter;GO:0022012;GO:0021554//optic nerve development;GO:0030323//respiratory tube development;GO:0051604//protein maturation;GO:0001568//blood vessel development;GO:0009611//response to wounding;GO:0021799//cerebral cortex radially oriented cell migration gi|120953173|ref|NP_032156.2|/0/transcriptional activator GLI3 [Mus musculus] 111002 1043 0.143333333 0.09 -0.671377253 Down 0.142295686 Marcksl1-ps4 "MARCKS-like 1, pseudogene 4" K13536|1|6e-29|130|mmu:17357|MARCKS-related protein GO:0016020//membrane;GO:0044424 GO:0005515//protein binding GO:0006810//transport;GO:0008283//cell proliferation gi|507694744|ref|XP_004643003.1|/3.45107e-28/PREDICTED: MARCKS-related protein [Octodon degus] 21818 4144 0.243333333 0.306666667 0.333737397 Up 0.142248674 Tgm3 "transglutaminase 3, E polypeptide" K05620|1|0.0|1377|mmu:21818|transglutaminase 3 [EC:2.3.2.13] GO:0005856//cytoskeleton;GO:0009898//cytoplasmic side of plasma membrane "GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0046872//metal ion binding;GO:0016755//transferase activity, transferring amino-acyl groups" GO:0045229//external encapsulating structure organization;GO:0051259//protein oligomerization;GO:0006464//cellular protein modification process;GO:0009154//purine ribonucleotide catabolic process;GO:0030216//keratinocyte differentiation gi|124001551|ref|NP_033400.2|/0/protein-glutamine gamma-glutamyltransferase E precursor [Mus musculus] 18991 3013 0.306666667 0.243333333 -0.333737397 Down 0.142248674 Pou3f1 "POU domain, class 3, transcription factor 1" "K09365|1|1e-120|437|mmu:18991|POU domain transcription factor, class 3" GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding" GO:0014044//Schwann cell development;GO:0006366//transcription from RNA polymerase II promoter;GO:0009913//epidermal cell differentiation;GO:0007420//brain development;GO:0008366//axon ensheathment "gi|7106383|ref|NP_035271.1|/9.91765e-120/POU domain, class 3, transcription factor 1 [Mus musculus]" 71169 7256 4.94 4.74 -0.059623983 Down 0.142229869 Nbas neuroblastoma amplified sequence K20473|1|0.0|4431|mmu:71169|neuroblastoma-amplified sequence - - - gi|255003837|ref|NP_081982.1|/0/neuroblastoma-amplified sequence [Mus musculus] 209361 4821 4.943333333 5.146666667 0.058154155 Up 0.142229869 Taf3 TATA-box binding protein associated factor 3 K14650|1|0.0|1117|mmu:209361|transcription initiation factor TFIID subunit 3 GO:0043234//protein complex;GO:0044446;GO:0005634//nucleus GO:0005515//protein binding GO:0044763;GO:0006366//transcription from RNA polymerase II promoter;GO:0051179//localization;GO:0044092//negative regulation of molecular function "gi|57242908|gb|AAH89030.1|/0/TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, partial [Mus musculus]" 76051 4818 2.306666667 2.173333333 -0.085900073 Down 0.14219226 Ganc "glucosidase, alpha; neutral C" K12317|1|0.0|1846|mmu:76051|neutral alpha-glucosidase C [EC:3.2.1.20] - "GO:0004558//alpha-1,4-glucosidase activity;GO:0005488//binding" GO:0044238//primary metabolic process gi|124487339|ref|NP_766260.2|/0/neutral alpha-glucosidase C [Mus musculus] 80732 5546.34 2.223333333 2.093333333 -0.086922202 Down 0.14219226 Mynn myoneurin K10500|1|3e-70|270|bacu:103010937|zinc finger and BTB domain-containing protein 17;K09228|4|1e-60|238|tup:102496238|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|41056113|ref|NP_085034.2|/0/myoneurin isoform 1 [Mus musculus] 12795 2485 2.06 2.186666667 0.086088977 Up 0.14219226 Plk3 polo-like kinase 3 K08862|1|0.0|1146|mmu:12795|polo-like kinase 3 [EC:2.7.11.21] - - - - 56224 3168 2.2 2.066666667 -0.090197809 Down 0.14219226 Tspan5 tetraspanin 5 K17345|1|1e-137|315|pale:102898335|tetraspanin-5 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0044699;GO:0044699 gi|9625045|ref|NP_062517.1|/1.13183e-136/tetraspanin-5 [Mus musculus] 72023 4113.92 2.33 2.196666667 -0.08501399 Down 0.14219226 Cyb561d1 cytochrome b-561 domain containing 1 K08371|1|6e-38|162|shr:100925329|cytochrome b-561 domain containing protein 2 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0043169//cation binding GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy gi|880918536|ref|XP_005076693.2|/4.33789e-116/PREDICTED: cytochrome b561 domain-containing protein 1 isoform X1 [Mesocricetus auratus] 18573 3756.31 2.22 2.086666667 -0.08935952 Down 0.14219226 Pde1a "phosphodiesterase 1A, calmodulin-dependent" "K13755|1|0.0|1024|mmu:18573|calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]" GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0044444//cytoplasmic part "GO:0005515//protein binding;GO:0030551//cyclic nucleotide binding;GO:0043169//cation binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0005515//protein binding;GO:0030551//cyclic nucleotide binding;GO:0043169//cation binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity" GO:0007599//hemostasis;GO:0042127//regulation of cell proliferation;GO:0038127//ERBB signaling pathway;GO:0010660//regulation of muscle cell apoptotic process;GO:0010863//positive regulation of phospholipase C activity;GO:0046058//cAMP metabolic process;GO:0009154//purine ribonucleotide catabolic process;GO:0007599//hemostasis;GO:0042127//regulation of cell proliferation;GO:0038127//ERBB signaling pathway;GO:0010660//regulation of muscle cell apoptotic process;GO:0010863//positive regulation of phospholipase C activity;GO:0046058//cAMP metabolic process;GO:0009154//purine ribonucleotide catabolic process gi|1399700|gb|AAB03319.1|/0/cyclic nucleotide phosphodiesterase [Mus musculus] 216578 3776 2.193333333 2.066666667 -0.085819368 Down 0.14219226 Papolg poly(A) polymerase gamma K14376|1|0.0|1416|mmu:216578|poly(A) polymerase [EC:2.7.7.19] - "GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0032550;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0031123//RNA 3'-end processing gi|226494207|ref|NP_766143.2|/0/poly(A) polymerase gamma [Mus musculus] 70552 2554 1.886666667 2.013333333 0.093746496 Up 0.14219226 Lrrc56 leucine rich repeat containing 56 - - - - gi|60359886|dbj|BAD90162.1|/0/mFLJ00101 protein [Mus musculus] 207521 5786 2.16 2.293333333 0.086414752 Up 0.14219226 Dtx4 "deltex 4, E3 ubiquitin ligase" K06058|1|0.0|1165|mmu:207521|deltex [EC:2.3.2.27] - - - - 192198 3636 0.256666667 0.32 0.31817596 Up 0.142107638 Lrrc4 leucine rich repeat containing 4 K16351|1|0.0|1256|mmu:192198|netrin-G2 ligand GO:0097060//synaptic membrane;GO:0031224//intrinsic component of membrane - - gi|532045959|ref|XP_005365779.1|/0/PREDICTED: leucine-rich repeat-containing protein 4 [Microtus ochrogaster] 71750 4053.26 93.90666667 96.00333333 0.031856917 Up 0.142107638 R3hdm2 R3H domain containing 2 K02360|1|3e-36|157|nvi:100123797|a component of the cytoplasm (encore) GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0097159//organic cyclic compound binding;GO:0097159//organic cyclic compound binding;GO:0097159//organic cyclic compound binding - gi|28972564|dbj|BAC65698.1|/0/mKIAA1002 protein [Mus musculus] 74442 5791 0.243333333 0.303333333 0.317970081 Up 0.142107638 Sgms2 sphingomyelin synthase 2 K04714|1|0.0|708|mmu:74442|shingomyelin synthase [EC:2.7.8.27] GO:0016021//integral component of membrane;GO:0031228//intrinsic component of Golgi membrane "GO:0016780//phosphotransferase activity, for other substituted phosphate groups" GO:0006684//sphingomyelin metabolic process gi|27229211|ref|NP_083219.2|/0/phosphatidylcholine:ceramide cholinephosphotransferase 2 [Mus musculus] 20964 3211 0.23 0.286666667 0.317740298 Up 0.142107638 Syn1 synapsin I K19941|1|0.0|796|mmu:20964|synapsin - - - - 234684 1930 0.23 0.286666667 0.317740298 Up 0.142107638 Lrrc29 leucine rich repeat containing 29 K10275|1|1e-170|546|cge:100760321|F-box and leucine-rich repeat protein 9 - - - gi|74195261|dbj|BAE28358.1|/0/unnamed protein product [Mus musculus] 666794 3224 92.89 94.95 0.031644708 Up 0.142098236 Rbm24 RNA binding motif protein 24 K14411|1|2e-11|74.7|bta:505542|RNA-binding protein Musashi;K13044|3|2e-11|74.3|hro:HELRODRAFT_94668|heterogeneous nuclear ribonucleoprotein A/B/D;K12741|4|2e-11|74.3|cin:100184318|heterogeneous nuclear ribonucleoprotein A1/A3 - - - - 94242 1954.98 102.4166667 100.3566667 -0.029314052 Down 0.142098236 Tinagl1 tubulointerstitial nephritis antigen-like 1 K01363|1|3e-40|169|obi:106873643|cathepsin B [EC:3.4.22.1] GO:0044424;GO:0044424 "GO:0001871;GO:0038024//cargo receptor activity;GO:0005515//protein binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0001871;GO:0038024//cargo receptor activity;GO:0005515//protein binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0002376//immune system process;GO:0019538//protein metabolic process;GO:0002376//immune system process gi|270132817|ref|NP_075965.2|/0/tubulointerstitial nephritis antigen-like precursor [Mus musculus] 224904 755 96.44333333 94.45333333 -0.030079804 Down 0.14199481 2410015M20Rik RIKEN cDNA 2410015M20 gene - GO:0043231//intracellular membrane-bounded organelle - - gi|23346595|ref|NP_694792.1|/3.78112e-62/MICOS complex subunit MIC13 precursor [Mus musculus] 380850 3292 0.13 0.083333333 -0.641546029 Down 0.141976005 Gm5141 predicted gene 5141 K09228|1|0.0|1274|mmu:380850|KRAB domain-containing zinc finger protein - - - gi|366039961|ref|NP_001242994.1|/0/zinc-finger protein 80-like [Mus musculus] 666348 2227 0.13 0.083333333 -0.641546029 Down 0.141976005 Apol7e apolipoprotein L 7e K14480|1|4e-135|484|mmu:666348|apolipoprotein L - - - gi|198278477|ref|NP_001128274.1|/3.78453e-134/apolipoprotein L 7e [Mus musculus] 319251 2811 0.09 0.14 0.637429921 Up 0.141976005 9630001P10Rik RIKEN cDNA 9630001P10 gene - - - - "gi|148705678|gb|EDL37625.1|/1.79767e-83/mCG146327, isoform CRA_a, partial [Mus musculus]" 13682 2534.17 89.91666667 91.86666667 0.030952928 Up 0.141919591 Eif4a2 eukaryotic translation initiation factor 4A2 K03257|1|0.0|779|pale:102885896|translation initiation factor 4A GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0032550;GO:0042623//ATPase activity, coupled;GO:0008135//translation factor activity, RNA binding;GO:0032550;GO:0042623//ATPase activity, coupled;GO:0008135//translation factor activity, RNA binding;GO:0032550;GO:0042623//ATPase activity, coupled;GO:0008135//translation factor activity, RNA binding;GO:0032550;GO:0042623//ATPase activity, coupled;GO:0008135//translation factor activity, RNA binding" "GO:0006413//translational initiation;GO:0007166//cell surface receptor signaling pathway;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006413//translational initiation;GO:0007166//cell surface receptor signaling pathway;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006413//translational initiation;GO:0007166//cell surface receptor signaling pathway;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006413//translational initiation;GO:0007166//cell surface receptor signaling pathway;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" "gi|148665241|gb|EDK97657.1|/0/eukaryotic translation initiation factor 4A2, isoform CRA_c, partial [Mus musculus]" 16412 4194 87.95333333 89.85 0.030780248 Up 0.141816165 Itgb1 integrin beta 1 (fibronectin receptor beta) K05719|1|0.0|1578|mmu:16412|integrin beta 1 GO:0009986//cell surface;GO:0043209//myelin sheath;GO:0005578//proteinaceous extracellular matrix;GO:0030141//secretory granule;GO:0045202//synapse;GO:0048770;GO:0008305//integrin complex;GO:0001726//ruffle;GO:0044291//cell-cell contact zone;GO:0005924//cell-substrate adherens junction GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0033218//amide binding;GO:0043169//cation binding;GO:0046983//protein dimerization activity;GO:0042805//actinin binding GO:0010810//regulation of cell-substrate adhesion;GO:0048871//multicellular organismal homeostasis;GO:0007160//cell-matrix adhesion;GO:0009612//response to mechanical stimulus;GO:0030239//myofibril assembly;GO:0043009//chordate embryonic development;GO:0016337//single organismal cell-cell adhesion;GO:0035051//cardiocyte differentiation;GO:0016477//cell migration;GO:0044772//mitotic cell cycle phase transition;GO:0001934//positive regulation of protein phosphorylation;GO:0010975//regulation of neuron projection development;GO:0010212//response to ionizing radiation;GO:0006886//intracellular protein transport;GO:0007276//gamete generation;GO:0006897//endocytosis;GO:0045165//cell fate commitment;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0007043//cell-cell junction assembly;GO:0033280//response to vitamin D;GO:0007565//female pregnancy;GO:0043066//negative regulation of apoptotic process;GO:0000165//MAPK cascade;GO:0002040//sprouting angiogenesis;GO:0006875//cellular metal ion homeostasis;GO:0009725//response to hormone gi|45504394|ref|NP_034708.1|/0/integrin beta-1 precursor [Mus musculus] 12321 3229 103.7166667 101.82 -0.026626775 Down 0.141816165 Calu calumenin K19934|1|1e-36|157|sko:100368121|calcium-binding protein GO:0005788//endoplasmic reticulum lumen;GO:0048770;GO:0005788//endoplasmic reticulum lumen;GO:0048770;GO:0005788//endoplasmic reticulum lumen;GO:0048770 GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding GO:0031103//axon regeneration;GO:0044092//negative regulation of molecular function;GO:0010033//response to organic substance;GO:0001775//cell activation;GO:0031103//axon regeneration;GO:0044092//negative regulation of molecular function;GO:0006887//exocytosis;GO:0007599//hemostasis;GO:0010033//response to organic substance;GO:0001775//cell activation;GO:0044092//negative regulation of molecular function;GO:0006887//exocytosis;GO:0007599//hemostasis gi|41282022|ref|NP_908942.1|/0/calumenin isoform 2 precursor [Mus musculus] 19038 1286 14.25666667 13.87 -0.039668919 Down 0.141787957 Ppic peptidylprolyl isomerase C K09563|1|6e-101|370|mmu:19038|peptidyl-prolyl isomerase C (cyclophilin C) [EC:5.2.1.8] GO:0044424 GO:0008144//drug binding;GO:0033218//amide binding;GO:0016859//cis-trans isomerase activity GO:0044267//cellular protein metabolic process gi|6679441|ref|NP_032934.1|/5.04084e-100/peptidyl-prolyl cis-trans isomerase C precursor [Mus musculus] 67804 2013 14.51666667 14.90333333 0.037924827 Up 0.141787957 Snx2 sorting nexin 2 K17917|1|0.0|845|mmu:67804|sorting nexin-1/2 GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005543//phospholipid binding;GO:0022892//substrate-specific transporter activity GO:0044763;GO:0015031//protein transport gi|13385878|ref|NP_080662.1|/0/sorting nexin-2 [Mus musculus] 69752 1100 6.66 6.913333333 0.053859311 Up 0.141778555 Zfp511 zinc finger protein 511 - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" "gi|148685942|gb|EDL17889.1|/3.74659e-143/mCG21614, isoform CRA_d [Mus musculus]" 72330 2455 7.643333333 7.393333333 -0.047976989 Down 0.141778555 Klhl40 kelch-like 40 K10473|1|0.0|1206|mmu:72330|kelch repeat and BTB domain-containing protein 5/10 - - - - 17873 1305 7.17 7.416666667 0.048797811 Up 0.141778555 Gadd45b growth arrest and DNA-damage-inducible 45 beta K04402|1|3e-76|288|mmu:17873|growth arrest and DNA-damage-inducible protein GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0012501//programmed cell death;GO:0050896//response to stimulus;GO:0048869//cellular developmental process;GO:0032147//activation of protein kinase activity;GO:0007049//cell cycle;GO:0001933//negative regulation of protein phosphorylation gi|6678980|ref|NP_032681.1|/2.58152e-75/growth arrest and DNA damage-inducible protein GADD45 beta [Mus musculus] 66439 2176 7 7.25 0.050626073 Up 0.141778555 Borcs7 BLOC-1 related complex subunit 7 - - - - gi|545547811|ref|XP_535001.3|/4.59885e-52/PREDICTED: UPF0693 protein C10orf32 homolog [Canis lupus familiaris] 225348 3020.53 6.823333333 6.576666667 -0.053120146 Down 0.141778555 Wdr36 WD repeat domain 36 K14554|1|0.0|1159|mmu:225348|U3 small nucleolar RNA-associated protein 21 - - GO:0048638//regulation of developmental growth;GO:0048638//regulation of developmental growth;GO:0048638//regulation of developmental growth "gi|148664650|gb|EDK97066.1|/0/WD repeat domain 36, isoform CRA_b, partial [Mus musculus]" 66259 3613 6.933333333 7.18 0.050434722 Up 0.141778555 Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 - GO:0044297//cell body;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane "GO:0004860//protein kinase inhibitor activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019900//kinase binding" GO:0007267//cell-cell signaling;GO:0001933//negative regulation of protein phosphorylation gi|74152877|dbj|BAB24979.3|/1.14559e-46/unnamed protein product [Mus musculus] 170938 2963 7.62 7.87 0.046572638 Up 0.141778555 Zfp617 zinc finger protein 617 K09228|1|0.0|1209|mmu:170938|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|126723419|ref|NP_579936.2|/0/zinc finger protein 617 [Mus musculus] 27392 6777 0.9 0.813333333 -0.146078259 Down 0.14175975 Pign "phosphatidylinositol glycan anchor biosynthesis, class N" "K05285|1|0.0|1617|mmu:27392|phosphatidylinositol glycan, class N [EC:2.7.-.-]" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006497//protein lipidation gi|167900470|ref|NP_038812.2|/0/GPI ethanolamine phosphate transferase 1 [Mus musculus] 241322 4535 0.836666667 0.926666667 0.147397519 Up 0.14175975 Zbtb6 zinc finger and BTB domain containing 6 K10493|1|0.0|863|mmu:241322|zinc finger and BTB domain-containing protein 6 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|22122841|ref|NP_666365.1|/0/zinc finger and BTB domain-containing protein 6 [Mus musculus] 382620 7179 0.856666667 0.95 0.14919356 Up 0.14175975 Tmed8 transmembrane emp24 domain containing 8 - GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization gi|84794627|ref|NP_001028647.1|/3.52425e-153/protein TMED8 [Mus musculus] 93681 8800 0.883333333 0.796666667 -0.148981741 Down 0.14175975 Zkscan8 zinc finger with KRAB and SCAN domains 8 K09229|1|0.0|1051|mmu:93681|KRAB and SCAN domains-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0044764;GO:0006351//transcription, DNA-templated;GO:0044764;GO:0006351//transcription, DNA-templated" gi|353249892|ref|NP_001238762.1|/0/zinc finger protein 192 isoform 2 [Mus musculus] 243197 2508 0.823333333 0.913333333 0.149664851 Up 0.14175975 Mfsd7a major facilitator superfamily domain containing 7A "K12306|1|0.0|930|mmu:243197|MFS transporter, FLVCR family, MFS-domain-containing protein 7" GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763 gi|27370346|ref|NP_766471.1|/0/major facilitator superfamily domain-containing protein 7 [Mus musculus] 69169 1491 0.1 0.15 0.584962501 Up 0.141731543 Fcmr Fc fragment of IgM receptor K13073|1|2e-10|69.7|cfa:474357|polymeric immunoglobulin receptor;K16851|4|2e-09|66.6|cfr:102507528|high affinity immunoglobulin alpha and immunoglobulin mu Fc receptor GO:0031224//intrinsic component of membrane - - gi|62460639|ref|NP_081252.1|/0/fas apoptotic inhibitory molecule 3 precursor [Mus musculus] 22413 2115 0.146666667 0.096666667 -0.601450624 Down 0.141731543 Wnt2 "wingless-type MMTV integration site family, member 2" "K00182|1|0.0|728|mmu:22413|wingless-type MMTV integration site family, member 2" GO:0016020//membrane;GO:0044424;GO:0044421;GO:0031012//extracellular matrix GO:0005109//frizzled binding GO:0030879//mammary gland development;GO:0071363//cellular response to growth factor stimulus;GO:0048568//embryonic organ development;GO:0006366//transcription from RNA polymerase II promoter;GO:0001837//epithelial to mesenchymal transition;GO:0001935//endothelial cell proliferation;GO:0003209//cardiac atrium morphogenesis;GO:0001759//organ induction;GO:0030323//respiratory tube development;GO:0044093;GO:0050679//positive regulation of epithelial cell proliferation;GO:0030177//positive regulation of Wnt signaling pathway gi|242397432|ref|NP_076142.3|/0/protein Wnt-2 precursor [Mus musculus] 67062 3208 0.1 0.15 0.584962501 Up 0.141731543 Slc25a53 "solute carrier family 25, member 53" "K15110|1|7e-10|68.9|aqu:100638500|solute carrier family 25 (mitochondrial 2-oxodicarboxylate transporter), member 21" GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0051234//establishment of localization gi|126723223|ref|NP_001075881.1|/0/solute carrier family 25 member 53 isoform 1 precursor [Mus musculus] 213742 14637.58 0.15 0.1 -0.584962501 Down 0.141731543 Xist inactive X specific transcripts K09566|1|4e-09|68.9|tup:102480013|peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8];K12875|3|1e-08|67.0|crg:105337759|apoptotic chromatin condensation inducer in the nucleus - - - - 76074 2459 0.093333333 0.143333333 0.618909833 Up 0.141731543 Gbp8 guanylate-binding protein 8 K17339|1|4e-10|69.7|spu:575529|atlastin [EC:3.6.5.-] - GO:0005488//binding GO:0001932//regulation of protein phosphorylation;GO:0006606//protein import into nucleus;GO:0016567//protein ubiquitination;GO:0032480//negative regulation of type I interferon production;GO:0034341//response to interferon-gamma;GO:0002697 gi|83776551|ref|NP_083785.3|/0/guanylate binding protein 8 [Mus musculus] 21940 1576 0.1 0.153333333 0.61667136 Up 0.141731543 Cd27 CD27 antigen K05144|1|9e-103|376|mmu:21940|tumor necrosis factor receptor superfamily member 7 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0044425 GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity GO:0030217//T cell differentiation;GO:0006915//apoptotic process;GO:0042095//interferon-gamma biosynthetic process;GO:0002377//immunoglobulin production;GO:0007254//JNK cascade;GO:0012502//induction of programmed cell death;GO:0097305//response to alcohol;GO:0042113//B cell activation;GO:0030217//T cell differentiation;GO:0006915//apoptotic process;GO:0042095//interferon-gamma biosynthetic process;GO:0002377//immunoglobulin production;GO:0007254//JNK cascade;GO:0012502//induction of programmed cell death;GO:0097305//response to alcohol;GO:0042113//B cell activation;GO:0030217//T cell differentiation;GO:0006915//apoptotic process;GO:0042095//interferon-gamma biosynthetic process;GO:0002377//immunoglobulin production;GO:0007254//JNK cascade;GO:0012502//induction of programmed cell death;GO:0097305//response to alcohol;GO:0042113//B cell activation gi|557948013|ref|NP_001273682.1|/6.89504e-114/CD27 antigen isoform c precursor [Mus musculus] 14409 1835 1.4 1.293333333 -0.114332675 Down 0.141487081 Gabrr2 "gamma-aminobutyric acid (GABA) C receptor, subunit rho 2" K05190|1|0.0|974|mmu:14409|gamma-aminobutyric acid receptor subunit rho GO:0043005//neuron projection;GO:0097060//synaptic membrane;GO:0034702//ion channel complex GO:0005253//anion channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0016917//GABA receptor activity;GO:0005515//protein binding GO:0050953//sensory perception of light stimulus;GO:0015698//inorganic anion transport;GO:0001754//eye photoreceptor cell differentiation;GO:0007186//G-protein coupled receptor signaling pathway "gi|148673544|gb|EDL05491.1|/0/mCG12753, isoform CRA_b, partial [Mus musculus]" 75286 580 2.67 2.813333333 0.075440756 Up 0.141487081 4930549G23Rik RIKEN cDNA 4930549G23 gene K14299|1|8e-18|92.0|oaa:100086897|nucleoporin SEH1 - - - - 14711 1042 2.46 2.32 -0.08453351 Down 0.141487081 Gnmt glycine N-methyltransferase K00552|1|3e-173|609|mmu:14711|glycine N-methyltransferase [EC:2.1.1.20] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0008170//N-methyltransferase activity;GO:0016597//amino acid binding GO:0006073//cellular glucan metabolic process;GO:0051260//protein homooligomerization;GO:0000096//sulfur amino acid metabolic process;GO:0006094//gluconeogenesis;GO:0006760//folic acid-containing compound metabolic process gi|6754026|ref|NP_034451.1|/2.74683e-172/glycine N-methyltransferase [Mus musculus] 269132 4080 2.47 2.33 -0.084181087 Down 0.141487081 Colgalt2 collagen beta(1-O)galactosyltransferase 2 "K11703|1|0.0|1219|mmu:269132|collagen beta-1,O-galactosyltransferase [EC:2.4.1.50]" - - - gi|228008340|ref|NP_808424.3|/0/procollagen galactosyltransferase 2 precursor [Mus musculus] 27081 6283 1.55 1.436666667 -0.109542847 Down 0.141487081 Zfp275 zinc finger protein 275 K09228|1|0.0|989|rno:293849|KRAB domain-containing zinc finger protein - - - gi|237681073|ref|NP_113682.2|/0/zinc finger protein 275 isoform 1 [Mus musculus] 69309 2528 1.393333333 1.506666667 0.11281983 Up 0.141487081 Slc16a13 "solute carrier family 16 (monocarboxylic acid transporters), member 13" "K08189|1|0.0|729|mmu:69309|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 13" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0051234//establishment of localization;GO:0044763 gi|29336097|ref|NP_758959.1|/0/monocarboxylate transporter 13 [Mus musculus] 94093 8819 1.51 1.4 -0.109121722 Down 0.141487081 Trim33 tripartite motif-containing 33 K08883|1|0.0|1783|mmu:94093|tripartite motif-containing protein 33 [EC:2.3.2.27] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046332//SMAD binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046332//SMAD binding GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0032446//protein modification by small protein conjugation;GO:0030509//BMP signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0032446//protein modification by small protein conjugation;GO:0030509//BMP signaling pathway gi|37360250|dbj|BAC98103.1|/0/mKIAA1113 protein [Mus musculus] 76355 2265 2.58 2.44 -0.080489918 Down 0.141487081 Tgds "TDP-glucose 4,6-dehydratase" "K01710|1|0.0|731|mmu:76355|dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]" - GO:0036094//small molecule binding;GO:0048037//cofactor binding;GO:0016836//hydro-lyase activity GO:0009117//nucleotide metabolic process "gi|148668237|gb|EDL00567.1|/0/TDP-glucose 4,6-dehydratase, isoform CRA_d, partial [Mus musculus]" 74206 7713 2.473333333 2.336666667 -0.082004743 Down 0.141487081 Sipa1l3 signal-induced proliferation-associated 1 like 3 K17703|1|0.0|3306|mmu:74206|signal-induced proliferation-associated 1 like protein 3 - - - gi|124486630|ref|NP_001074497.1|/0/signal-induced proliferation-associated 1-like protein 3 [Mus musculus] 269254 10970 2.416666667 2.28 -0.08398467 Down 0.141487081 Setx senataxin K10706|1|0.0|5030|mmu:269254|senataxin [EC:3.6.4.-] GO:0031981//nuclear lumen GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0006281//DNA repair;GO:0048511//rhythmic process;GO:0006366//transcription from RNA polymerase II promoter gi|113722131|ref|NP_932150.2|/0/probable helicase senataxin [Mus musculus] 101187 3724 1.493333333 1.606666667 0.105534414 Up 0.141487081 Parp11 "poly (ADP-ribose) polymerase family, member 11" K15259|1|0.0|641|mmu:101187|poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30] - "GO:0016763//transferase activity, transferring pentosyl groups" - "gi|148667444|gb|EDK99860.1|/0/poly (ADP-ribose) polymerase family, member 11, isoform CRA_b, partial [Mus musculus]" 12554 3913 87.96 89.67666667 0.027885049 Up 0.141449472 Cdh13 cadherin 13 "K06808|1|0.0|1364|mmu:12554|cadherin 13, H-cadherin" - - - - 243621 6982.65 0.496666667 0.423333333 -0.230483834 Down 0.14140246 Iqsec3 IQ motif and Sec7 domain 3 K12495|1|0.0|813|bom:102275321|IQ motif and SEC7 domain-containing protein - - - gi|84781690|ref|NP_001028526.1|/0/IQ motif and SEC7 domain-containing protein 3 isoform 1 [Mus musculus] 93708 4708 0.396666667 0.466666667 0.234465254 Up 0.14140246 Pcdhgc5 "protocadherin gamma subfamily C, 5" K16497|1|0.0|1670|mmu:93708|protocadherin gamma subfamily C - - - gi|18087751|ref|NP_291061.1|/0/protocadherin gamma-C5 precursor [Mus musculus] 100416706 4835 0.426666667 0.5 0.22881869 Up 0.14140246 Zfp729b zinc finger protein 729b K09228|1|0.0|2256|mmu:100416706|KRAB domain-containing zinc finger protein - - - - 16433 2270 0.456666667 0.39 -0.227667363 Down 0.14140246 Cuzd1 CUB and zona pellucida-like domains 1 K13912|1|0.0|659|gja:107116292|deleted in malignant brain tumors 1 protein GO:0031224//intrinsic component of membrane;GO:0030667//secretory granule membrane - GO:0031638//zymogen activation;GO:0044703;GO:0022610;GO:0007165//signal transduction gi|133778951|ref|NP_032437.3|/0/CUB and zona pellucida-like domain-containing protein 1 precursor [Mus musculus] 230971 6876 0.433333333 0.506666667 0.2255597 Up 0.14140246 Megf6 multiple EGF-like-domains 6 K02258|1|5e-159|565|hmg:100209451|cytochrome c oxidase assembly protein subunit 11 - GO:0046872//metal ion binding - gi|244790081|ref|NP_001156449.1|/0/multiple epidermal growth factor-like domains protein 6 precursor [Mus musculus] 67245 3501 3.583333333 3.423333333 -0.065900478 Down 0.14136485 Peli1 pellino 1 K11964|1|0.0|877|fch:102045967|pellino [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0019787//ubiquitin-like protein transferase activity;GO:0005488//binding GO:0000209//protein polyubiquitination;GO:0007166//cell surface receptor signaling pathway;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0030888//regulation of B cell proliferation;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0001816//cytokine production;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0014070//response to organic cyclic compound;GO:0002237//response to molecule of bacterial origin;GO:0042098//T cell proliferation gi|537273922|gb|ERE92513.1|/0/putative E3 ubiquitin-protein ligase pellino-like protein [Cricetulus griseus] 14156 2106 3.223333333 3.383333333 0.069891933 Up 0.14136485 Fen1 flap structure specific endonuclease 1 K04799|1|4e-174|614|mmu:14156|flap endonuclease-1 [EC:3.-.-.-] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0003676//nucleic acid binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0046914//transition metal ion binding;GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters;GO:0004527//exonuclease activity;GO:0003676//nucleic acid binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0046914//transition metal ion binding;GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters;GO:0004527//exonuclease activity;GO:0003676//nucleic acid binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0046914//transition metal ion binding;GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters;GO:0004527//exonuclease activity" GO:0006281//DNA repair;GO:0007611//learning or memory;GO:0006281//DNA repair;GO:0007611//learning or memory;GO:0006281//DNA repair;GO:0007611//learning or memory "gi|148709395|gb|EDL41341.1|/0/flap structure specific endonuclease 1, isoform CRA_b, partial [Mus musculus]" 22025 3827 3.346666667 3.186666667 -0.070676746 Down 0.14136485 Nr2c1 "nuclear receptor subfamily 2, group C, member 1" K08543|1|0.0|1162|mmu:22025|testicular receptor 2 GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0019899//enzyme binding "GO:0006351//transcription, DNA-templated;GO:0009755//hormone-mediated signaling pathway;GO:0009967//positive regulation of signal transduction" gi|171846245|ref|NP_035759.3|/0/nuclear receptor subfamily 2 group C member 1 [Mus musculus] 21853 4476 3.18 3.343333333 0.072260435 Up 0.14136485 Timeless timeless circadian clock 1 K03155|1|0.0|1900|mmu:21853|timeless GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding "GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0010564//regulation of cell cycle process;GO:0030323//respiratory tube development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0033554//cellular response to stress;GO:0000087//mitotic M phase;GO:0007623//circadian rhythm;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0010564//regulation of cell cycle process;GO:0030323//respiratory tube development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0033554//cellular response to stress;GO:0000087//mitotic M phase;GO:0007623//circadian rhythm;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0010564//regulation of cell cycle process;GO:0030323//respiratory tube development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0033554//cellular response to stress;GO:0000087//mitotic M phase;GO:0007623//circadian rhythm;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0010564//regulation of cell cycle process;GO:0030323//respiratory tube development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0033554//cellular response to stress;GO:0000087//mitotic M phase;GO:0007623//circadian rhythm" gi|568967418|ref|XP_006513643.1|/0/PREDICTED: protein timeless homolog isoform X2 [Mus musculus] 242291 4636 3.486666667 3.323333333 -0.069217442 Down 0.14136485 Impad1 inositol monophosphatase domain containing 1 K15759|1|0.0|641|mmu:242291|inositol monophosphatase 3 [EC:3.1.3.25 3.1.3.7] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0052834//inositol monophosphate phosphatase activity;GO:0008252//nucleotidase activity GO:0046488//phosphatidylinositol metabolic process;GO:0002062//chondrocyte differentiation;GO:0006790//sulfur compound metabolic process;GO:0006020//inositol metabolic process;GO:0036075;GO:0030326//embryonic limb morphogenesis gi|29244210|ref|NP_808398.1|/0/inositol monophosphatase 3 [Mus musculus] 114663 1386 12.37333333 12.75333333 0.043640163 Up 0.141355448 Impa2 inositol (myo)-1(or 4)-monophosphatase 2 K01092|1|3e-164|580|mmu:114663|myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] GO:0044424 GO:0043169//cation binding;GO:0052834//inositol monophosphate phosphatase activity;GO:0042802//identical protein binding GO:0046488//phosphatidylinositol metabolic process;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0006020//inositol metabolic process;GO:0007154//cell communication gi|74181837|dbj|BAE32621.1|/0/unnamed protein product [Mus musculus] 21413 7161.28 14.9 15.28 0.036332213 Up 0.141355448 Tcf4 transcription factor 4 K15603|1|0.0|1157|cge:100767684|transcription factor 4/12 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0001091;GO:0046983//protein dimerization activity;GO:0001083;GO:0043566//structure-specific DNA binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0034622//cellular macromolecular complex assembly;GO:0030182//neuron differentiation gi|625253836|ref|XP_007618256.1|/0/PREDICTED: transcription factor 4 isoform X2 [Cricetulus griseus] 17261 5437 69.65333333 71.34666667 0.034653632 Up 0.141336643 Mef2d myocyte enhancer factor 2D K09262|1|0.0|746|chx:102174260|MADS-box transcription enhancer factor 2D GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0019899//enzyme binding;GO:0008134//transcription factor binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0019899//enzyme binding;GO:0008134//transcription factor binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0012501//programmed cell death;GO:0007507//heart development;GO:0036075;GO:0007519//skeletal muscle tissue development;GO:0030154//cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0012501//programmed cell death;GO:0007507//heart development;GO:0036075;GO:0007519//skeletal muscle tissue development;GO:0030154//cell differentiation gi|19526812|ref|NP_598426.1|/0/myocyte-specific enhancer factor 2D isoform 2 [Mus musculus] 57296 1529 85.43 87.08333333 0.027653849 Up 0.141233217 Psmd8 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 8" K03031|1|7e-161|569|mmu:57296|26S proteasome regulatory subunit N12 GO:0031981//nuclear lumen;GO:0022624//proteasome accessory complex;GO:0044444//cytoplasmic part - "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0006915//apoptotic process;GO:0044764;GO:0051320;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|156713423|ref|NP_080821.3|/5.51491e-160/26S proteasome non-ATPase regulatory subunit 8 [Mus musculus] 102632 3348 66.50333333 64.91 -0.034985898 Down 0.141101583 Acad11 "acyl-Coenzyme A dehydrogenase family, member 11" K11730|1|0.0|1579|mmu:102632|acyl-CoA dehydrogenase family member 11 GO:0005929//cilium;GO:0042579//microbody;GO:0005740//mitochondrial envelope GO:0000166//nucleotide binding;GO:0016740//transferase activity;GO:0004466//long-chain-acyl-CoA dehydrogenase activity GO:0006635//fatty acid beta-oxidation;GO:0007369//gastrulation;GO:0045596//negative regulation of cell differentiation;GO:0001822//kidney development;GO:0009855//determination of bilateral symmetry;GO:0030178//negative regulation of Wnt signaling pathway;GO:0007601//visual perception gi|74271799|ref|NP_780533.2|/0/acyl-CoA dehydrogenase family member 11 [Mus musculus] 67675 702.6 65.79333333 64.21666667 -0.034993627 Down 0.141082779 Cuta cutA divalent cation tolerance homolog K03926|1|3e-55|151|mmu:67675|periplasmic divalent cation tolerance protein - - - - 14456 2594 79.54 81.10666667 0.028139941 Up 0.141045169 Gas6 growth arrest specific 6 K05464|1|0.0|1281|mmu:14456|growth arrest-specific 6 GO:0044421;GO:0044424 GO:0005262//calcium channel activity;GO:0046872//metal ion binding;GO:0030295//protein kinase activator activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005102//receptor binding;GO:0005543//phospholipid binding "GO:0001678//cellular glucose homeostasis;GO:0000060//protein import into nucleus, translocation;GO:0034351//negative regulation of glial cell apoptotic process;GO:0044092//negative regulation of molecular function;GO:0006612//protein targeting to membrane;GO:0009887//organ morphogenesis;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0046718//viral entry into host cell;GO:0032692//negative regulation of interleukin-1 production;GO:0001779//natural killer cell differentiation;GO:0019062//virion attachment to host cell;GO:0002407//dendritic cell chemotaxis;GO:0008284//positive regulation of cell proliferation;GO:0022607//cellular component assembly;GO:0048247//lymphocyte chemotaxis;GO:0031214//biomineral tissue development;GO:0006611//protein export from nucleus;GO:0061082;GO:0035701//hematopoietic stem cell migration;GO:0006351//transcription, DNA-templated;GO:0019058//viral life cycle;GO:0007155//cell adhesion;GO:0040007//growth;GO:0035455//response to interferon-alpha;GO:0043410//positive regulation of MAPK cascade;GO:0033554//cellular response to stress;GO:0032147//activation of protein kinase activity;GO:0042493//response to drug;GO:0070848//response to growth factor;GO:0006909//phagocytosis;GO:0032675//regulation of interleukin-6 production;GO:0032571//response to vitamin K;GO:0097048;GO:0003093//regulation of glomerular filtration;GO:0006816//calcium ion transport;GO:0007599//hemostasis" gi|145301603|ref|NP_062394.2|/0/growth arrest-specific protein 6 precursor [Mus musculus] 215751 1557 63.30666667 64.86 0.03497159 Up 0.140998157 Ginm1 glycoprotein integral membrane 1 - GO:0031224//intrinsic component of membrane - - gi|21703834|ref|NP_663393.1|/9.61856e-168/glycoprotein integral membrane protein 1 precursor [Mus musculus] 218952 3243 72.07666667 70.53666667 -0.031158892 Down 0.140960548 Fermt2 fermitin family member 2 K17083|1|0.0|1281|mmu:218952|kindlin 2 - - - - 71446 2483 4.743333333 4.933333333 0.056661514 Up 0.140951145 Wrb tryptophan rich basic protein - GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0031981//nuclear lumen - - gi|46409250|ref|NP_997184.1|/2.39238e-92/tail-anchored protein insertion receptor WRB [Mus musculus] 14431 960 4.91 4.716666667 -0.057955377 Down 0.140951145 Gamt guanidinoacetate methyltransferase K00542|1|7e-127|455|mmu:14431|guanidinoacetate N-methyltransferase [EC:2.1.1.2] GO:0044464 GO:0042802//identical protein binding;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity GO:0006790//sulfur compound metabolic process;GO:0035264//multicellular organism growth;GO:0048232//male gamete generation;GO:0006600//creatine metabolic process;GO:0009653//anatomical structure morphogenesis gi|6753944|ref|NP_034385.1|/5.75208e-126/guanidinoacetate N-methyltransferase [Mus musculus] 60596 4671 4.513333333 4.326666667 -0.060937356 Down 0.140951145 Gucy1a3 "guanylate cyclase 1, soluble, alpha 3" K12318|1|0.0|1347|mmu:60596|guanylate cyclase soluble subunit alpha [EC:4.6.1.2] GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0032550;GO:0046983//protein dimerization activity;GO:0046906//tetrapyrrole binding;GO:0016829//lyase activity;GO:0009975//cyclase activity GO:0010033//response to organic substance;GO:0042311//vasodilation;GO:0006182//cGMP biosynthetic process;GO:0006950//response to stress;GO:0052551;GO:0019932//second-messenger-mediated signaling gi|31981219|ref|NP_068696.2|/0/guanylate cyclase soluble subunit alpha-3 [Mus musculus] 18750 8385 4.246666667 4.06 -0.064851144 Down 0.140951145 Prkca "protein kinase C, alpha" K02677|1|0.0|1407|mmu:18750|classical protein kinase C alpha type [EC:2.7.11.13] GO:0031981//nuclear lumen;GO:0005740//mitochondrial envelope;GO:0044425;GO:0031513//nonmotile primary cilium;GO:0043005//neuron projection;GO:0032991//macromolecular complex;GO:0044297//cell body GO:0004697//protein kinase C activity;GO:0046914//transition metal ion binding;GO:0035184//histone threonine kinase activity;GO:0005515//protein binding;GO:0032550 GO:0034097//response to cytokine;GO:0015980//energy derivation by oxidation of organic compounds;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0009743//response to carbohydrate;GO:0051384//response to glucocorticoid;GO:0006979//response to oxidative stress;GO:0007409//axonogenesis;GO:0006875//cellular metal ion homeostasis;GO:0044089//positive regulation of cellular component biogenesis;GO:0007416//synapse assembly;GO:0010543//regulation of platelet activation;GO:0030595//leukocyte chemotaxis;GO:0043407//negative regulation of MAP kinase activity;GO:0038127//ERBB signaling pathway;GO:0044708//single-organism behavior;GO:0001525//angiogenesis;GO:0097305//response to alcohol;GO:0030073//insulin secretion;GO:0043066//negative regulation of apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0006954//inflammatory response;GO:0009636//response to toxic substance;GO:0002934//desmosome organization;GO:0003300//cardiac muscle hypertrophy;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0008016//regulation of heart contraction;GO:0016070//RNA metabolic process;GO:0000278//mitotic cell cycle;GO:0010595//positive regulation of endothelial cell migration;GO:0045762//positive regulation of adenylate cyclase activity;GO:0002833;GO:0008104//protein localization;GO:0007155//cell adhesion;GO:0010829//negative regulation of glucose transport;GO:0043627//response to estrogen;GO:0006412//translation;GO:0035405;GO:0001935//endothelial cell proliferation;GO:0006898//receptor-mediated endocytosis;GO:0043410//positive regulation of MAPK cascade;GO:0050927//positive regulation of positive chemotaxis;GO:0006936//muscle contraction;GO:0006887//exocytosis;GO:0008286//insulin receptor signaling pathway;GO:0010863//positive regulation of phospholipase C activity gi|164663791|ref|NP_035231.2|/0/protein kinase C alpha type [Mus musculus] 19170 1036 86.61 88.12666667 0.025045029 Up 0.140941743 Psmb1 "proteasome (prosome, macropain) subunit, beta type 1" K02732|1|1e-134|481|mmu:19170|20S proteasome subunit beta 6 [EC:3.4.25.1] GO:0043231//intracellular membrane-bounded organelle;GO:0000502//proteasome complex GO:0004175//endopeptidase activity GO:0006508//proteolysis gi|7242197|ref|NP_035315.1|/1.11714e-133/proteasome subunit beta type-1 precursor [Mus musculus] 100042480 12971 0.593333333 0.673333333 0.182478052 Up 0.140857121 Nhsl2 NHS-like 2 - - - - gi|254692837|ref|NP_001157082.1|/0/NHS-like protein 2 [Mus musculus] 11745 1619 13.57666667 13.20333333 -0.040227113 Down 0.140838317 Anxa3 annexin A3 K17089|1|0.0|639|mmu:11745|annexin A3 GO:0043005//neuron projection;GO:0030666//endocytic vesicle membrane;GO:0030141//secretory granule;GO:0044297//cell body GO:0005543//phospholipid binding;GO:0046872//metal ion binding;GO:0004859//phospholipase inhibitor activity GO:0001525//angiogenesis;GO:0010594//regulation of endothelial cell migration;GO:0002283//neutrophil activation involved in immune response;GO:0006259//DNA metabolic process;GO:0044092//negative regulation of molecular function;GO:0044093;GO:0006897//endocytosis;GO:0006952//defense response gi|160707925|ref|NP_038498.2|/0/annexin A3 [Mus musculus] 53620 1648 14.08333333 13.71666667 -0.038058911 Down 0.140838317 Vamp5 vesicle-associated membrane protein 5 K08514|1|2e-36|155|mmu:53620|vesicle-associated membrane protein 5 GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane - GO:0014706//striated muscle tissue development;GO:0006886//intracellular protein transport;GO:0048513//animal organ development;GO:0048869//cellular developmental process;GO:0014706//striated muscle tissue development;GO:0006886//intracellular protein transport;GO:0048513//animal organ development;GO:0048869//cellular developmental process gi|13661881|gb|AAK38123.1|/3.96872e-57/CAMP protein [Mus musculus] 78893 2990 12.97 13.34333333 0.040940635 Up 0.140838317 Cnot10 "CCR4-NOT transcription complex, subunit 10" K12607|1|0.0|1411|mmu:78893|CCR4-NOT transcription complex subunit 10 GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0005488//binding "GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" "gi|148677354|gb|EDL09301.1|/0/CCR4-NOT transcription complex, subunit 10, isoform CRA_b, partial [Mus musculus]" 210766 1448.67 12.04666667 12.41666667 0.043643919 Up 0.140838317 Brcc3 "BRCA1/BRCA2-containing complex, subunit 3" K11864|1|5e-144|513|mmu:210766|BRCA1/BRCA2-containing complex subunit 3 GO:0043231//intracellular membrane-bounded organelle;GO:0000151//ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000151//ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000151//ubiquitin ligase complex GO:0043169//cation binding;GO:0016790//thiolester hydrolase activity;GO:0043130//ubiquitin binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0043169//cation binding;GO:0016790//thiolester hydrolase activity;GO:0043130//ubiquitin binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0043169//cation binding;GO:0016790//thiolester hydrolase activity;GO:0043130//ubiquitin binding;GO:0019783//ubiquitin-like protein-specific protease activity GO:0006281//DNA repair;GO:0010212//response to ionizing radiation;GO:0019222//regulation of metabolic process;GO:0016578//histone deubiquitination;GO:0000077//DNA damage checkpoint;GO:0006281//DNA repair;GO:0010212//response to ionizing radiation;GO:0019222//regulation of metabolic process;GO:0016578//histone deubiquitination;GO:0000077//DNA damage checkpoint;GO:0006281//DNA repair;GO:0010212//response to ionizing radiation;GO:0019222//regulation of metabolic process;GO:0016578//histone deubiquitination;GO:0000077//DNA damage checkpoint gi|12848275|dbj|BAB27894.1|/2.13384e-142/unnamed protein product [Mus musculus] 11774 4020 12.99 12.61666667 -0.042070631 Down 0.140838317 Ap3b1 "adaptor-related protein complex 3, beta 1 subunit" K12397|1|0.0|1833|mmu:11774|AP-3 complex subunit beta GO:0030119//AP-type membrane coat adaptor complex;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle GO:0019902//phosphatase binding GO:0001865//NK T cell differentiation;GO:0007599//hemostasis;GO:0048753//pigment granule organization;GO:0006623//protein targeting to vacuole;GO:0019884//antigen processing and presentation of exogenous antigen;GO:0048489//synaptic vesicle transport;GO:0008088//axo-dendritic transport;GO:0000041//transition metal ion transport gi|163310776|ref|NP_033810.2|/0/AP-3 complex subunit beta-1 [Mus musculus] 227800 4942.15 6.963333333 6.726666667 -0.049886318 Down 0.1407725 Rabgap1 RAB GTPase activating protein 1 K20284|1|0.0|1934|mmu:227800|Rab GTPase-activating protein 1 GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part;GO:0043232 GO:0008092//cytoskeletal protein binding;GO:0003676//nucleic acid binding GO:0044763;GO:0044763 gi|76880498|ref|NP_001029132.1|/0/rab GTPase-activating protein 1 isoform b [Mus musculus] 11568 4073.47 7.466666667 7.703333333 0.045018528 Up 0.1407725 Aebp1 AE binding protein 1 K08639|1|0.0|791|lcm:102359684|carboxypeptidase X2 - - - - 101869 3285 7.51 7.75 0.045383403 Up 0.1407725 Unc45a unc-45 myosin chaperone A K17766|1|1e-16|92.0|xma:102218483|mitochondrial import receptor subunit TOM34;K20097|2|1e-15|88.2|myd:102767626|FK506-binding protein-like GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0031072//heat shock protein binding GO:0006457//protein folding;GO:0048513//animal organ development;GO:0048869//cellular developmental process gi|227908790|ref|NP_598713.2|/0/protein unc-45 homolog A [Mus musculus] 71661 1122 0.48 0.413333333 -0.215728691 Down 0.140706683 0610005C13Rik RIKEN cDNA 0610005C13 gene - - - - - 51791 2356 0.51 0.436666667 -0.223964841 Down 0.140706683 Rgs14 regulator of G-protein signaling 14 K17706|1|0.0|984|mmu:51791|regulator of G-protein signaling 14 - - - gi|31980626|ref|NP_058038.2|/0/regulator of G-protein signaling 14 [Mus musculus] 75734 1807.14 61.29 62.73666667 0.033657173 Up 0.140687878 Mff mitochondrial fission factor - - - - - 79555 2551 64.65666667 63.25 -0.031733652 Down 0.140556245 BC005537 cDNA sequence BC005537 - GO:0044464 - - gi|291395715|ref|XP_002714269.1|/8.70475e-122/PREDICTED: uncharacterized protein C6orf62 homolog isoform X1 [Oryctolagus cuniculus] 70762 4044.16 0.313333333 0.253333333 -0.306661338 Down 0.140499831 Dclk2 doublecortin-like kinase 2 K08805|1|0.0|992|mmu:70762|doublecortin-like kinase 1/2 [EC:2.7.11.1] GO:0043232;GO:0043232;GO:0043232;GO:0043232;GO:0043232;GO:0043232 GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007165//signal transduction;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007165//signal transduction;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007165//signal transduction;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007165//signal transduction;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007165//signal transduction;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007165//signal transduction gi|306922352|ref|NP_001182427.1|/0/serine/threonine-protein kinase DCLK2 isoform 4 [Mus musculus] 668137 1573 0.236666667 0.293333333 0.309684499 Up 0.140499831 Gm8994 predicted gene 8994 K13025|1|0.0|811|mmu:668137|ATP-dependent RNA helicase [EC:3.6.4.13] GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0003724//RNA helicase activity;GO:0032550;GO:0008135//translation factor activity, RNA binding;GO:0042623//ATPase activity, coupled;GO:0003729//mRNA binding" "GO:0007166//cell surface receptor signaling pathway;GO:0050658//RNA transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0006412//translation;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000398//mRNA splicing, via spliceosome;GO:0042254//ribosome biogenesis" "gi|218505708|ref|NP_001136206.1|/0/predicted gene, EG668137 [Mus musculus]" 99662 2313 0.11 0.16 0.540568381 Up 0.140330588 Eps8l3 EPS8-like 3 K17277|1|0.0|1120|mmu:99662|epidermal growth factor receptor kinase substrate 8 GO:0044424 - - gi|19527082|ref|NP_598628.1|/0/epidermal growth factor receptor kinase substrate 8-like protein 3 [Mus musculus] 100043434 936 0.113333333 0.166666667 0.556393349 Up 0.140330588 Gm4432 predicted gene 4432 K02915|1|1e-24|116|ocu:100339329|large subunit ribosomal protein L34e - - - gi|826324385|ref|XP_012510584.1|/3.95355e-28/PREDICTED: 60S ribosomal protein L34 [Propithecus coquereli] 13844 10926.75 0.106666667 0.156666667 0.554588852 Up 0.140330588 Ephb2 Eph receptor B2 K05111|1|0.0|1940|mmu:13844|Eph receptor B2 [EC:2.7.10.1] - - - - 75015 1048 0.143333333 0.096666667 -0.56828376 Down 0.140330588 4930503B20Rik RIKEN cDNA 4930503B20 gene K09512|1|1e-30|135|mgp:100546860|DnaJ homolog subfamily B member 6;K09509|4|7e-30|133|mcf:102124732|DnaJ homolog subfamily B member 3 GO:0043231//intracellular membrane-bounded organelle - - gi|126722682|ref|NP_083420.2|/3.53202e-135/sterile alpha motif domain-containing protein 13 [Mus musculus] 73094 4851 0.166666667 0.113333333 -0.556393349 Down 0.140330588 Sgip1 SH3-domain GRB2-like (endophilin) interacting protein 1 K20065|1|0.0|1177|mmu:73094|SH3-containing GRB2-like protein 3-interacting protein 1 GO:0030128//clathrin coat of endocytic vesicle GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0015631//tubulin binding GO:0006898//receptor-mediated endocytosis gi|21536264|ref|NP_659155.1|/0/SH3-containing GRB2-like protein 3-interacting protein 1 isoform b [Mus musculus] 64085 4494 0.1 0.146666667 0.552541023 Up 0.140330588 Clstn2 calsyntenin 2 K04600|1|9e-11|72.8|lcm:102357994|cadherin EGF LAG seven-pass G-type receptor 1;K16506|2|9e-11|72.8|ggo:101145539|protocadherin Fat 1/2/3;K04601|5|1e-10|72.4|cmk:103179175|cadherin EGF LAG seven-pass G-type receptor 2 GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0097060//synaptic membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion;GO:0007267//cell-cell signaling gi|40254527|ref|NP_071714.2|/0/calsyntenin-2 precursor [Mus musculus] 12478 2440 0.103333333 0.15 0.537656786 Up 0.140330588 Cd19 CD19 antigen K06465|1|0.0|905|mmu:12478|CD19 antigen GO:0009986//cell surface;GO:0031224//intrinsic component of membrane - GO:0050851//antigen receptor-mediated signaling pathway gi|74179159|dbj|BAE42774.1|/0/unnamed protein product [Mus musculus] 93875 3719 0.103333333 0.153333333 0.569365646 Up 0.140330588 Pcdhb4 protocadherin beta 4 K16494|1|0.0|1481|mmu:93875|protocadherin beta GO:0005856//cytoskeleton;GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|113866009|ref|NP_444359.3|/0/protocadherin beta 4 precursor [Mus musculus] 622554 1613 0.096666667 0.143333333 0.56828376 Up 0.140330588 1700123I01Rik membrane anchored junction protein - - - - - 229877 3583.6 14.08666667 14.45 0.036739226 Up 0.140311783 Rap1gds1 "RAP1, GTP-GDP dissociation stimulator 1" K16739|1|9e-12|57.0|chx:102176913|nuclear distribution protein NudE-like 1;K08332|4|3e-09|67.4|crg:105344622|vacuolar protein 8;K15043|5|3e-07|60.8|apla:101805178|importin subunit alpha-2 - - - gi|100818462|ref|NP_663519.2|/0/rap1 GTPase-GDP dissociation stimulator 1 isoform b [Mus musculus] 71707 2970 12.66333333 12.3 -0.041998896 Down 0.140311783 Ubiad1 UbiA prenyltransferase domain containing 1 - GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups" GO:0042362//fat-soluble vitamin biosynthetic process;GO:0009233 gi|21311819|ref|NP_082149.1|/2.13557e-175/ubiA prenyltransferase domain-containing protein 1 [Mus musculus] 223649 2537 13.99 13.62666667 -0.037963267 Down 0.140311783 Nrbp2 nuclear receptor binding protein 2 K08875|1|3e-176|621|ngi:103735275|nuclear receptor-binding protein GO:0044424 GO:0016301//kinase activity;GO:0036094//small molecule binding GO:0006464//cellular protein modification process;GO:0010507//negative regulation of autophagy;GO:0030154//cell differentiation;GO:0043066//negative regulation of apoptotic process "gi|148697579|gb|EDL29526.1|/3.23588e-177/nuclear receptor binding protein 2, isoform CRA_b [Mus musculus]" 76429 1607 13.40333333 13.04333333 -0.039279226 Down 0.140311783 Lhpp phospholysine phosphohistidine inorganic pyrophosphate phosphatase K11725|1|5e-135|483|mmu:76429|phospholysine phosphohistidine inorganic pyrophosphate phosphatase [EC:3.6.1.1 3.1.3.-] GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0016791//phosphatase activity;GO:0016462//pyrophosphatase activity GO:0006793//phosphorus metabolic process;GO:0006464//cellular protein modification process gi|70778744|ref|NP_083885.1|/4.26569e-134/phospholysine phosphohistidine inorganic pyrophosphate phosphatase [Mus musculus] 242960 2855 14.04333333 13.68333333 -0.037465694 Down 0.140311783 Fbxl5 F-box and leucine-rich repeat protein 5 K10271|1|0.0|1185|mmu:242960|F-box and leucine-rich repeat protein 5 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0044444//cytoplasmic part;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0055080//cation homeostasis;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation;GO:0055080//cation homeostasis;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation gi|229577156|ref|NP_001153435.1|/0/F-box/LRR-repeat protein 5 isoform A [Mus musculus] 18712 1769 13.47 13.83333333 0.038398985 Up 0.140311783 Pim1 proviral integration site 1 K04702|1|0.0|646|mmu:18712|proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1] GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0032550;GO:0005515//protein binding;GO:0004672//protein kinase activity GO:0006915//apoptotic process;GO:0031657//regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0044092//negative regulation of molecular function;GO:0032502//developmental process gi|83305340|sp|P06803.2|PIM1_MOUSE/0/RecName: Full=Serine/threonine-protein kinase pim-1 69089 2534 62.03333333 63.37333333 0.030832251 Up 0.140302381 Oxa1l oxidase assembly 1-like K03217|1|0.0|764|mmu:69089|YidC/Oxa1 family membrane protein insertase GO:0032991//macromolecular complex;GO:0031301//integral component of organelle membrane;GO:0005740//mitochondrial envelope;GO:0019866//organelle inner membrane GO:0043022//ribosome binding;GO:0042802//identical protein binding GO:0043462//regulation of ATPase activity;GO:0043086//negative regulation of catalytic activity;GO:0010257//NADH dehydrogenase complex assembly;GO:0051259//protein oligomerization;GO:0045333//cellular respiration;GO:0007005//mitochondrion organization gi|58037139|ref|NP_081212.1|/0/mitochondrial inner membrane protein OXA1L [Mus musculus] 70771 4825.91 0.276666667 0.34 0.297385911 Up 0.140264771 Gpr173 G-protein coupled receptor 173 - - - - - 56847 3423 0.316666667 0.256666667 -0.303069068 Down 0.140264771 Aldh1a3 "aldehyde dehydrogenase family 1, subfamily A3" K00129|1|0.0|1016|mmu:56847|aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5] GO:0044444//cytoplasmic part "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0042562//hormone binding;GO:0042802//identical protein binding;GO:0043168//anion binding" GO:0021536//diencephalon development;GO:0042221//response to chemical;GO:0001523//retinoid metabolic process;GO:0048562//embryonic organ morphogenesis;GO:0043010//camera-type eye development;GO:0021756//striatum development;GO:0006915//apoptotic process;GO:0043584//nose development;GO:0016102//diterpenoid biosynthetic process;GO:0016331//morphogenesis of embryonic epithelium gi|170650621|ref|NP_444310.3|/0/aldehyde dehydrogenase family 1 member A3 [Mus musculus] 53375 1258 56.83 58.14666667 0.033043774 Up 0.140255369 Mtx2 metaxin 2 K17776|1|5e-151|536|mmu:53375|metaxin GO:0031966//mitochondrial membrane - GO:0019538//protein metabolic process;GO:0006605//protein targeting gi|228480241|ref|NP_058084.3|/3.93735e-150/metaxin-2 [Mus musculus] 70025 1496.16 59.74 58.41666667 -0.032317199 Down 0.140255369 Acot7 acyl-CoA thioesterase 7 K17360|1|0.0|717|mmu:70025|acyl-coenzyme A thioesterase 7 [EC:3.1.2.2] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0042995//cell projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0042995//cell projection GO:0043168//anion binding;GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0043168//anion binding;GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0043168//anion binding;GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity GO:0006631//fatty acid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006631//fatty acid metabolic process gi|225690618|ref|NP_001139530.1|/0/cytosolic acyl coenzyme A thioester hydrolase isoform 3 [Mus musculus] 73723 721 58.36333333 57.05333333 -0.032751105 Down 0.140245966 Sh3bgrl3 SH3 domain binding glutamic acid-rich protein-like 3 "K13912|1|3e-14|80.9|xma:102221819|deleted in malignant brain tumors 1 protein;K03877|2|1e-08|62.4|tgu:100227439|beta-1,3-galactosyltransferase 5 [EC:2.4.1.-];K16342|3|3e-06|54.3|nve:NEMVE_v1g199410|cytosolic phospholipase A2 [EC:3.1.1.4]" GO:0043231//intracellular membrane-bounded organelle GO:0015036//disulfide oxidoreductase activity GO:0044710;GO:0019725//cellular homeostasis "gi|159162524|pdb|1J0F|A/1.30299e-45/Chain A, Solution Structure Of The Sh3 Domain Binding Glutamic Acid- Rich Protein Like 3" 79221 4815.25 1.336666667 1.233333333 -0.116076966 Down 0.140236564 Hdac9 histone deacetylase 9 K11409|1|0.0|1706|rno:687001|histone deacetylase 9 [EC:3.5.1.98] GO:0043231//intracellular membrane-bounded organelle;GO:0034708 GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0017136//NAD-dependent histone deacetylase activity;GO:0008134//transcription factor binding GO:0048641//regulation of skeletal muscle tissue development;GO:0032868//response to insulin;GO:0006366//transcription from RNA polymerase II promoter;GO:0016575//histone deacetylation;GO:0051146//striated muscle cell differentiation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0030098//lymphocyte differentiation;GO:0006952//defense response gi|70778861|ref|NP_077038.2|/0/histone deacetylase 9 isoform 2 [Mus musculus] 72635 5183 1.256666667 1.153333333 -0.123792486 Down 0.140236564 Lins1 lines homolog 1 K04710|1|6e-97|257|gga:426648|ceramide synthetase [EC:2.3.1.24] - - - - 18766 7058 1.096666667 1.193333333 0.121872004 Up 0.140236564 Pkdrej polycystin (PKD) family receptor for egg jelly K19921|1|0.0|4101|mmu:18766|polycystic kidney disease and receptor for egg jelly-related protein GO:0016020//membrane - GO:0007340//acrosome reaction gi|115583675|ref|NP_035235.2|/0/polycystic kidney disease and receptor for egg jelly-related protein precursor [Mus musculus] 54218 1599 1.22 1.323333333 0.117295359 Up 0.140236564 B3galt4 "UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4" K00715|1|0.0|654|mmu:54218|ganglioside galactosyltransferase [EC:2.4.1.62] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0035250//UDP-galactosyltransferase activity GO:0006464//cellular protein modification process "gi|9506417|ref|NP_062293.1|/0/beta-1,3-galactosyltransferase 4 [Mus musculus]" 73915 881 1.21 1.313333333 0.118226081 Up 0.140236564 4833419F23Rik RIKEN cDNA 4833419F23 gene - - - - - 20474 5572 1.143333333 1.246666667 0.124829694 Up 0.140236564 Six4 sine oculis-related homeobox 4 K15615|1|0.0|1239|mmu:20474|homeobox protein SIX4 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0051094//positive regulation of developmental process;GO:0048638//regulation of developmental growth;GO:0001656//metanephros development;GO:0006366//transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0014706//striated muscle tissue development;GO:0048534//hematopoietic or lymphoid organ development;GO:0008104//protein localization;GO:0042471//ear morphogenesis;GO:0022008//neurogenesis;GO:0014812//muscle cell migration;GO:0048704//embryonic skeletal system morphogenesis gi|33859632|ref|NP_035512.1|/0/homeobox protein SIX4 [Mus musculus] 78751 4916 1.146666667 1.243333333 0.116767066 Up 0.140236564 Zc3h6 zinc finger CCCH type containing 6 K14404|1|5e-08|63.9|ola:101173062|cleavage and polyadenylation specificity factor subunit 4;K15687|5|1e-07|62.8|tru:778013|E3 ubiquitin-protein ligase makorin [EC:2.3.2.27] - GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding - gi|156717216|ref|NP_848491.2|/0/zinc finger CCCH domain-containing protein 6 [Mus musculus] 30953 1662.59 60.77 62.05666667 0.030226914 Up 0.140208357 Schip1 schwannomin interacting protein 1 - - - - - 102465642 137 0.96 0.87 -0.142019005 Down 0.14018015 Mir7060 microRNA 7060 - - - - - 239099 5787.79 1.006666667 0.913333333 -0.140372656 Down 0.14018015 Homez homeodomain leucine zipper-encoding gene - GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148704381|gb|EDL36328.1|/0/mCG20893, isoform CRA_b, partial [Mus musculus]" 72556 1692 0.883333333 0.973333333 0.139976009 Up 0.14018015 Zfp566 zinc finger protein 566 K09228|1|0.0|827|mmu:72556|KRAB domain-containing zinc finger protein GO:0044464 GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|22779907|ref|NP_690027.1|/0/zinc finger protein 566 [Mus musculus] 21769 2664 56.33666667 57.61666667 0.032411993 Up 0.14014254 Zfand3 "zinc finger, AN1-type domain 3" K12163|1|2e-06|57.8|crg:105347363|AN1-type zinc finger and ubiquitin domain-containing protein 1 - GO:0046914//transition metal ion binding - gi|22507321|ref|NP_683728.1|/8.09703e-94/AN1-type zinc finger protein 3 [Mus musculus] 114229 3163 0.113333333 0.163333333 0.527247003 Up 0.140114333 Kiss1r KISS1 receptor K08374|1|0.0|715|mmu:114229|KISS1 receptor GO:0044464;GO:0016021//integral component of membrane GO:0008528//G-protein coupled peptide receptor activity;GO:0042277//peptide binding GO:0032233//positive regulation of actin filament bundle assembly;GO:0007186//G-protein coupled receptor signaling pathway;GO:0046879//hormone secretion;GO:0015909//long-chain fatty acid transport;GO:0008283//cell proliferation;GO:0007268//chemical synaptic transmission;GO:0019932//second-messenger-mediated signaling;GO:0016477//cell migration gi|16716571|ref|NP_444474.1|/0/kiSS-1 receptor [Mus musculus] 15116 2107 0.12 0.173333333 0.530514717 Up 0.140114333 Has1 hyaluronan synthase1 K00752|1|0.0|1003|mmu:15116|hyaluronan synthase [EC:2.4.1.212] GO:0016021//integral component of membrane GO:0008194//UDP-glycosyltransferase activity GO:0006024//glycosaminoglycan biosynthetic process;GO:0044238//primary metabolic process;GO:0022610;GO:0010761//fibroblast migration;GO:0036119//response to platelet-derived growth factor gi|6680169|ref|NP_032241.1|/0/hyaluronan synthase 1 [Mus musculus] 214058 6018 0.12 0.173333333 0.530514717 Up 0.140114333 Megf11 multiple EGF-like-domains 11 K02258|1|3e-146|522|hmg:100209451|cytochrome c oxidase assembly protein subunit 11 - - - gi|755529953|ref|XP_006511048.2|/0/PREDICTED: multiple epidermal growth factor-like domains protein 11 isoform X2 [Mus musculus] 232989 2884 56.02 54.74666667 -0.033170857 Down 0.140104931 Hnrnpul1 heterogeneous nuclear ribonucleoprotein U-like 1 K15047|1|5e-153|543|mmu:232989|heterogeneous nuclear ribonucleoprotein U-like protein 1 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding "GO:0051707//response to other organism;GO:0006351//transcription, DNA-templated;GO:0051707//response to other organism;GO:0006351//transcription, DNA-templated" gi|74212736|dbj|BAE33342.1|/0/unnamed protein product [Mus musculus] 56442 2889 65.70666667 66.93666667 0.026756954 Up 0.13994509 Serinc1 serine incorporator 1 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0005488//binding;GO:0015179//L-amino acid transmembrane transporter activity GO:0006644//phospholipid metabolic process;GO:0006575//cellular modified amino acid metabolic process;GO:0006643//membrane lipid metabolic process;GO:0043085//positive regulation of catalytic activity;GO:0015807//L-amino acid transport gi|9790269|ref|NP_062734.1|/0/serine incorporator 1 precursor [Mus musculus] 14241 2960 0.166666667 0.116666667 -0.514573173 Down 0.139869871 Foxl1 forkhead box L1 K09405|1|4e-149|531|mmu:14241|forkhead box protein L GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0009653//anatomical structure morphogenesis;GO:0006351//transcription, DNA-templated;GO:0007267//cell-cell signaling;GO:0006029//proteoglycan metabolic process;GO:0016055//Wnt signaling pathway;GO:0048513//animal organ development;GO:0044767//single-organism developmental process" gi|120952618|ref|NP_032050.2|/3.78235e-148/forkhead box protein L1 [Mus musculus] 227358 2835 0.156666667 0.11 -0.510194732 Down 0.139869871 Fam132b "family with sequence similarity 132, member B" - - - - - 14938 878 0.623333333 0.7 0.167351058 Up 0.139813457 Gzma granzyme A K01352|1|2e-153|543|mmu:14938|granzyme A [EC:3.4.21.78] - GO:0004175//endopeptidase activity;GO:0042802//identical protein binding GO:0051100//negative regulation of binding;GO:0032071//regulation of endodeoxyribonuclease activity;GO:0043086//negative regulation of catalytic activity gi|6754102|ref|NP_034500.1|/1.81095e-152/granzyme A precursor [Mus musculus] 223669 2785 0.6 0.676666667 0.173482821 Up 0.139813457 Zfp7 zinc finger protein 7 K09228|1|0.0|1454|mmu:223669|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|162287093|ref|NP_666021.2|/0/zinc finger protein 7 [Mus musculus] 100312471 921 0.023333333 0.06 1.362570079 Up 0.139813457 Vmn1r3 vomeronasal 1 receptor 3 K04614|1|2e-165|583|mmu:100042437|vomeronasal1 receptor GO:0016021//integral component of membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0010033//response to organic substance gi|285394257|ref|NP_001161007.1|/2.17074e-167/vomeronasal 1 receptor 3 [Mus musculus] 30925 2443 0.026666667 0.066666667 1.321928095 Up 0.139813457 Slamf6 SLAM family member 6 K16852|1|5e-172|607|mmu:30925|SLAM family member 6 GO:0016021//integral component of membrane - - gi|568910939|ref|XP_006496947.1|/2.17739e-177/PREDICTED: SLAM family member 6 isoform X1 [Mus musculus] 328845 2608 0.026666667 0.07 1.392317423 Up 0.139813457 Acsbg2 acyl-CoA synthetase bubblegum family member 2 K15013|1|0.0|1331|mmu:328845|long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0032550;GO:0015645//fatty acid ligase activity;GO:0016289//CoA hydrolase activity GO:0048869//cellular developmental process;GO:0009062//fatty acid catabolic process;GO:0048232//male gamete generation gi|84993736|ref|NP_001034203.1|/0/long-chain-fatty-acid--CoA ligase ACSBG2 [Mus musculus] 230587 2904 0.023333333 0.063333333 1.440572591 Up 0.139813457 Glis1 GLIS family zinc finger 1 K09232|1|0.0|1283|mmu:230587|zinc finger protein GLIS1/3 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0006366//transcription from RNA polymerase II promoter gi|568928848|ref|XP_006503035.1|/0/PREDICTED: zinc finger protein GLIS1 isoform X4 [Mus musculus] 243963 3580 0.07 0.026666667 -1.392317423 Down 0.139813457 Zfp473 zinc finger protein 473 K09228|1|0.0|1917|mmu:243963|KRAB domain-containing zinc finger protein - - - - 241794 2316 0.026666667 0.066666667 1.321928095 Up 0.139813457 Kcng1 "potassium voltage-gated channel, subfamily G, member 1" K04900|1|0.0|907|mmu:241794|potassium voltage-gated channel subfamily G member 1 - - - gi|124487487|ref|NP_001074603.1|/0/potassium voltage-gated channel subfamily G member 1 [Mus musculus] 229791 5690 0.06 0.023333333 -1.362570079 Down 0.139813457 Plppr4 phospholipid phosphatase related 4 K19582|1|0.0|1499|mmu:229791|lipid phosphate phosphatase-related protein type 3/4 GO:0016021//integral component of membrane;GO:0009986//cell surface GO:0005488//binding;GO:0016791//phosphatase activity GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0016311//dephosphorylation;GO:0043583//ear development gi|37359962|dbj|BAC97959.1|/0/mKIAA0455 protein [Mus musculus] 320014 3085 0.063333333 0.023333333 -1.440572591 Down 0.139813457 B930025P03Rik RIKEN cDNA B930025P03 gene - - - - "gi|148690102|gb|EDL22049.1|/2.01477e-59/mCG144710, partial [Mus musculus]" 67790 3402 0.056666667 0.02 -1.502500341 Down 0.139813457 Rab39b "RAB39B, member RAS oncogene family" K07925|1|1e-124|450|lve:103083371|Ras-related protein Rab-39B - - - - 76787 4882 0.023333333 0.066666667 1.514573173 Up 0.139813457 Ppfia3 "protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3" K10352|1|3e-07|61.2|smm:Smp_085540.6|myosin heavy chain;K17785|2|5e-07|60.5|hmg:100206620|mitofilin;K10421|3|8e-07|59.7|der:Dere_GG21085|CAP-Gly domain-containing linker protein 1;K16469|4|8e-07|59.7|lve:103080140|rootletin GO:0044424 GO:0005488//binding GO:0001505//regulation of neurotransmitter levels;GO:0048168//regulation of neuronal synaptic plasticity gi|256997198|dbj|BAI22792.1|/0/mKIAA0654 protein [Mus musculus] 58807 3175.04 0.066666667 0.023333333 -1.514573173 Down 0.139813457 Slco1c1 "solute carrier organic anion transporter family, member 1c1" "K08747|1|0.0|1348|mmu:58807|solute carrier organic anion transporter family, member 1C" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005319//lipid transporter activity;GO:0005319//lipid transporter activity GO:0015718//monocarboxylic acid transport;GO:0015718//monocarboxylic acid transport "gi|148678675|gb|EDL10622.1|/0/solute carrier organic anion transporter family, member 1c1, isoform CRA_a, partial [Mus musculus]" 230959 3067 0.023333333 0.06 1.362570079 Up 0.139813457 Ajap1 adherens junction associated protein 1 - GO:0044459;GO:0031224//intrinsic component of membrane - GO:0022610 gi|150010629|ref|NP_001092769.1|/0/adherens junction-associated protein 1 [Mus musculus] 76376 10516 0.026666667 0.07 1.392317423 Up 0.139813457 Slc24a2 "solute carrier family 24 (sodium/potassium/calcium exchanger), member 2" "K13750|1|0.0|1191|rno:84550|solute carrier family 24 (sodium/potassium/calcium exchanger), member 2" GO:0031224//intrinsic component of membrane GO:0031420;GO:0046914//transition metal ion binding;GO:0015081//sodium ion transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005515//protein binding;GO:0005261//cation channel activity GO:0050953//sensory perception of light stimulus;GO:0007611//learning or memory;GO:0006875//cellular metal ion homeostasis;GO:0048167//regulation of synaptic plasticity;GO:0006816//calcium ion transport gi|27369563|ref|NP_766014.1|/0/sodium/potassium/calcium exchanger 2 isoform 1 [Mus musculus] 320587 3471 0.676666667 0.6 -0.173482821 Down 0.139813457 Tmem88b transmembrane protein 88B "K03847|1|2e-06|58.2|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260];K10591|2|2e-06|58.2|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26];K09228|3|4e-06|57.0|rno:102551340|KRAB domain-containing zinc finger protein" - - - gi|260436875|ref|NP_001028566.2|/5.5018e-45/transmembrane protein 88B [Mus musculus] 72605 3339 0.023333333 0.06 1.362570079 Up 0.139813457 Car10 carbonic anhydrase 10 K18245|1|1e-36|158|phd:102333907|carbonic anhydrase 2 [EC:4.2.1.1];K01672|4|4e-35|153|tgu:100219624|carbonic anhydrase [EC:4.2.1.1] - - GO:0007417//central nervous system development gi|9910366|ref|NP_064563.1|/0/carbonic anhydrase-related protein 10 precursor [Homo sapiens] 58523 2789 11.63666667 11.29 -0.04363237 Down 0.13978525 Elp2 elongator acetyltransferase complex subunit 2 K11374|1|0.0|1674|mmu:58523|elongator complex protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003676//nucleic acid binding;GO:0019900//kinase binding;GO:0061135 GO:0007259//JAK-STAT cascade;GO:0043623//cellular protein complex assembly;GO:0010952//positive regulation of peptidase activity;GO:0006366//transcription from RNA polymerase II promoter gi|134032030|ref|NP_067423.2|/0/elongator complex protein 2 [Mus musculus] 231874 1786 11.98666667 11.63666667 -0.042752664 Down 0.13978525 Ccz1 CCZ1 vacuolar protein trafficking and biogenesis associated K08269|1|3e-30|135|tsp:Tsp_02012a|serine/threonine-protein kinase ULK/ATG1 [EC:2.7.11.1] GO:0000323//lytic vacuole - - gi|29244114|ref|NP_808350.1|/0/vacuolar fusion protein CCZ1 homolog [Mus musculus] 18541 9492.16 12.02666667 12.37666667 0.041385977 Up 0.13978525 Pcnt pericentrin (kendrin) K16481|1|0.0|4732|mmu:18541|pericentrin GO:0005813//centrosome;GO:0044421;GO:0005813//centrosome;GO:0044421 GO:0005515//protein binding;GO:0005515//protein binding GO:0016477//cell migration;GO:0012501//programmed cell death;GO:0010927;GO:0043009//chordate embryonic development;GO:0040007//growth;GO:0021988//olfactory lobe development;GO:0009887//organ morphogenesis;GO:0000226//microtubule cytoskeleton organization;GO:0035107//appendage morphogenesis;GO:0008283//cell proliferation;GO:0016477//cell migration;GO:0012501//programmed cell death;GO:0010927;GO:0043009//chordate embryonic development;GO:0040007//growth;GO:0021988//olfactory lobe development;GO:0009887//organ morphogenesis;GO:0000226//microtubule cytoskeleton organization;GO:0035107//appendage morphogenesis;GO:0008283//cell proliferation gi|93004085|ref|NP_032813.3|/0/pericentrin isoform a [Mus musculus] 56046 2668 66.73666667 65.53333333 -0.026250713 Down 0.13978525 Uqcc1 ubiquinol-cytochrome c reductase complex assembly factor 1 K17662|1|7e-173|610|mmu:56046|cytochrome b pre-mRNA-processing protein 3 GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle - - "gi|148674208|gb|EDL06155.1|/1.34943e-173/RIKEN cDNA 2410003P15, isoform CRA_d, partial [Mus musculus]" 30941 2200 11.53333333 11.88 0.042725299 Up 0.13978525 Usp21 ubiquitin specific peptidase 21 K11833|1|0.0|1018|mmu:30941|ubiquitin carboxyl-terminal hydrolase 2/21 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003712//transcription cofactor activity;GO:0016790//thiolester hydrolase activity;GO:0019783//ubiquitin-like protein-specific protease activity "GO:0019941//modification-dependent protein catabolic process;GO:0016570//histone modification;GO:0006351//transcription, DNA-templated" gi|224809307|ref|NP_038947.2|/0/ubiquitin carboxyl-terminal hydrolase 21 [Mus musculus] 66185 7115 3.033333333 2.88 -0.074835233 Down 0.139597202 1110037F02Rik RIKEN cDNA 1110037F02 gene K05741|1|3e-73|281|chx:102191777|diaphanous 2 - - - - 74762 7566 3.27 3.423333333 0.06611114 Up 0.139597202 Mdga1 MAM domain containing glycosylphosphatidylinositol anchor 1 K17341|1|5e-38|164|pon:100434687|hemicentin - - - gi|124487209|ref|NP_001074629.1|/0/MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor [Mus musculus] 83768 1684 3.076666667 2.93 -0.070467483 Down 0.139597202 Dpp7 dipeptidylpeptidase 7 K01276|1|0.0|984|mmu:83768|dipeptidyl-peptidase II [EC:3.4.14.2] GO:0000323//lytic vacuole;GO:0031982//vesicle GO:0008238//exopeptidase activity GO:0019538//protein metabolic process gi|31981425|ref|NP_114031.2|/0/dipeptidyl peptidase 2 precursor [Mus musculus] 13435 9689 3.39 3.24 -0.06529146 Down 0.139597202 Dnmt3a DNA methyltransferase 3A K17398|1|0.0|1380|mmu:13435|DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37] GO:0034399//nuclear periphery;GO:0000790//nuclear chromatin;GO:0034399//nuclear periphery;GO:0000790//nuclear chromatin;GO:0034399//nuclear periphery;GO:0000790//nuclear chromatin GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0043169//cation binding;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0043169//cation binding;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0043169//cation binding GO:0006366//transcription from RNA polymerase II promoter;GO:0006342//chromatin silencing;GO:0032776//DNA methylation on cytosine;GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0048232//male gamete generation;GO:0044026//DNA hypermethylation;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006342//chromatin silencing;GO:0032776//DNA methylation on cytosine;GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0048232//male gamete generation;GO:0044026//DNA hypermethylation;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0006342//chromatin silencing;GO:0032776//DNA methylation on cytosine;GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0048232//male gamete generation;GO:0044026//DNA hypermethylation;GO:0006325//chromatin organization gi|6681209|ref|NP_031898.1|/0/DNA (cytosine-5)-methyltransferase 3A isoform 1 [Mus musculus] 69736 1282 3.153333333 3 -0.071915182 Down 0.139597202 Nup37 nucleoporin 37 K14302|1|0.0|683|mmu:69736|nuclear pore complex protein Nup37 "GO:0005643//nuclear pore;GO:0000775//chromosome, centromeric region;GO:0005643//nuclear pore;GO:0000775//chromosome, centromeric region" - GO:0050658//RNA transport;GO:0045184//establishment of protein localization;GO:0000087//mitotic M phase;GO:0050658//RNA transport;GO:0045184//establishment of protein localization;GO:0000087//mitotic M phase gi|21312212|ref|NP_082610.1|/0/nucleoporin Nup37 [Mus musculus] 328563 2057 0.13 0.183333333 0.495957495 Up 0.139587799 Apol11b apolipoprotein L 11b K14480|1|9e-92|340|mmu:626615|apolipoprotein L - - - gi|219521911|ref|NP_001137158.1|/3.79005e-141/apolipoprotein L 11b [Mus musculus] 74035 3581.26 4.306666667 4.483333333 0.058000103 Up 0.139578397 Nol9 nucleolar protein 9 K06947|1|0.0|774|mmu:74035|polynucleotide 5'-hydroxyl-kinase GRC3/NOL9 [EC:2.7.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0003676//nucleic acid binding;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032550;GO:0003676//nucleic acid binding;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032550" GO:0006796//phosphate-containing compound metabolic process;GO:0006364//rRNA processing;GO:0006796//phosphate-containing compound metabolic process;GO:0006364//rRNA processing gi|227430356|ref|NP_083003.2|/0/polynucleotide 5'-hydroxyl-kinase NOL9 isoform 2 [Mus musculus] 56386 5808 4.396666667 4.22 -0.05916716 Down 0.139578397 B4galt6 "UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6" "K07553|1|0.0|776|mmu:56386|beta-1,4-galactosyltransferase 6 [EC:2.4.1.274]" GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0035250//UDP-galactosyltransferase activity GO:0006687//glycosphingolipid metabolic process "gi|9790037|ref|NP_062711.1|/0/beta-1,4-galactosyltransferase 6 [Mus musculus]" 20532 2307 4.376666667 4.196666667 -0.060588633 Down 0.139578397 Slc3a1 "solute carrier family 3, member 1" "K14210|1|0.0|1416|mmu:20532|solute carrier family 3 (neutral and basic amino acid transporter), member 1" GO:0019866//organelle inner membrane;GO:0016021//integral component of membrane GO:0046983//protein dimerization activity;GO:0043167//ion binding GO:0046942//carboxylic acid transport;GO:0044238//primary metabolic process gi|119120879|ref|NP_033231.2|/0/neutral and basic amino acid transport protein rBAT [Mus musculus] 67581 3664 4.443333333 4.26 -0.060788944 Down 0.139578397 Tbc1d23 "TBC1 domain family, member 23" K04707|1|4e-16|90.1|spu:100890602|E3 ubiquitin-protein ligase CBL [EC:2.3.2.27];K17544|2|3e-09|67.4|isc:IscW_ISCW008128|TBC domain-containing protein kinase-like protein;K20166|4|5e-07|60.1|clv:102095864|TBC1 domain family member 2B;K20168|5|6e-07|59.7|tad:TRIADDRAFT_38489|TBC1 domain family member 15 GO:0044464 - GO:0006954//inflammatory response;GO:0001819//positive regulation of cytokine production "gi|148665754|gb|EDK98170.1|/0/TBC1 domain family, member 23, isoform CRA_b, partial [Mus musculus]" 268936 5973 4.463333333 4.28 -0.060510758 Down 0.139578397 Brpf3 "bromodomain and PHD finger containing, 3" K11350|1|0.0|2230|mmu:268936|bromodomain and PHD finger-containing protein 3 GO:0070775 GO:0043169//cation binding GO:0016573//histone acetylation gi|124486783|ref|NP_001074784.1|/0/bromodomain and PHD finger-containing protein 3 [Mus musculus] 13006 4851 4.403333333 4.226666667 -0.059075721 Down 0.139578397 Smc3 structural maintenance of chromosomes 3 K06669|1|0.0|2101|mmu:13006|structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6) GO:0034399//nuclear periphery;GO:0005819//spindle;GO:0000795//synaptonemal complex;GO:0005578//proteinaceous extracellular matrix;GO:0000798//nuclear cohesin complex GO:0032550;GO:0046983//protein dimerization activity;GO:0003774//motor activity;GO:0032403//protein complex binding GO:0007154//cell communication;GO:0007067//mitotic nuclear division;GO:0007059//chromosome segregation;GO:0033554//cellular response to stress;GO:0010948//negative regulation of cell cycle process;GO:0032502//developmental process;GO:0006260//DNA replication gi|36031035|ref|NP_031816.2|/0/structural maintenance of chromosomes protein 3 [Mus musculus] 234582 2309 4.003333333 4.183333333 0.063451213 Up 0.139578397 Ccdc102a coiled-coil domain containing 102A K16759|1|0.0|879|mmu:234582|coiled-coil domain-containing protein 102A - - - gi|269973923|ref|NP_001028705.2|/0/coiled-coil domain-containing protein 102A [Mus musculus] 56275 3168 6.346666667 6.58 0.052088511 Up 0.139568995 Rbm14 RNA binding motif protein 14 K13189|1|3e-177|625|mmu:56275|RNA-binding protein 14 - - - - 329777 4761.1 6.273333333 6.043333333 -0.053887703 Down 0.139568995 Pigk "phosphatidylinositol glycan anchor biosynthesis, class K" "K05290|1|0.0|750|mmu:329777|phosphatidylinositol glycan, class K [EC:2.6.-.-]" GO:0030176//integral component of endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane "GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups;GO:0004175//endopeptidase activity;GO:0035091//phosphatidylinositol binding;GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups;GO:0004175//endopeptidase activity;GO:0035091//phosphatidylinositol binding" GO:0006497//protein lipidation;GO:0006497//protein lipidation gi|29789447|ref|NP_821135.1|/0/GPI-anchor transamidase isoform 2 precursor [Mus musculus] 217695 3869 7.333333333 7.566666667 0.045188774 Up 0.139568995 Zfyve1 "zinc finger, FYVE domain containing 1" K17603|1|0.0|1615|mmu:217695|zinc finger FYVE domain-containing protein 1 - - - "gi|148670790|gb|EDL02737.1|/0/zinc finger, FYVE domain containing 1, isoform CRA_a, partial [Mus musculus]" 68911 3209.89 6.966666667 7.2 0.04752837 Up 0.139568995 Pygo2 pygopus 2 K06279|1|3e-40|170|fpg:101919976|SHC-transforming protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0007417//central nervous system development;GO:0016055//Wnt signaling pathway;GO:0043010//camera-type eye development;GO:0040007//growth;GO:0033598//mammary gland epithelial cell proliferation;GO:0031060//regulation of histone methylation;GO:0007417//central nervous system development;GO:0016055//Wnt signaling pathway;GO:0043010//camera-type eye development;GO:0040007//growth;GO:0033598//mammary gland epithelial cell proliferation;GO:0031060//regulation of histone methylation;GO:0007417//central nervous system development;GO:0016055//Wnt signaling pathway;GO:0043010//camera-type eye development;GO:0040007//growth;GO:0033598//mammary gland epithelial cell proliferation;GO:0031060//regulation of histone methylation;GO:0007417//central nervous system development;GO:0016055//Wnt signaling pathway;GO:0043010//camera-type eye development;GO:0040007//growth;GO:0033598//mammary gland epithelial cell proliferation;GO:0031060//regulation of histone methylation;GO:0007417//central nervous system development;GO:0016055//Wnt signaling pathway;GO:0043010//camera-type eye development;GO:0040007//growth;GO:0033598//mammary gland epithelial cell proliferation;GO:0031060//regulation of histone methylation "gi|148683247|gb|EDL15194.1|/3.64435e-124/mCG145235, partial [Mus musculus]" 58185 3785 6.96 6.726666667 -0.049195537 Down 0.139568995 Rsad2 radical S-adenosyl methionine domain containing 2 K15045|1|0.0|706|mmu:58185|radical S-adenosyl methionine domain-containing protein 2 GO:0031966//mitochondrial membrane;GO:0019866//organelle inner membrane GO:0005515//protein binding;GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding "GO:0002726//positive regulation of T cell cytokine production;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0051707//response to other organism;GO:0035710//CD4-positive, alpha-beta T cell activation;GO:0009306//protein secretion;GO:0019079//viral genome replication;GO:0001503//ossification" gi|74177937|dbj|BAE29764.1|/0/unnamed protein product [Mus musculus] 78706 2168 0.03 0.073333333 1.289506617 Up 0.139521983 Platr4 pluripotency associated transcript 4 - - - - - 545654 549 0.073333333 0.03 -1.289506617 Down 0.139521983 Gm13285 predicted gene 13285 K05414|1|1e-38|160|cge:100763520|interferon alpha GO:0044421 GO:0005102//receptor binding GO:0007166//cell surface receptor signaling pathway;GO:0030098//lymphocyte differentiation;GO:0002252;GO:0007049//cell cycle;GO:0012501//programmed cell death gi|239050335|ref|NP_001155080.1|/2.85832e-102/interferon zeta-like precursor [Mus musculus] 414089 2017 0.073333333 0.03 -1.289506617 Down 0.139521983 Gja6 "gap junction protein, alpha 6" "K07615|1|3e-139|498|mmu:414089|gap junction protein, alpha 6;K07372|3|2e-84|316|myd:102768996|gap junction protein, alpha 1" GO:0005921//gap junction;GO:0031224//intrinsic component of membrane - GO:0007043//cell-cell junction assembly gi|47894401|ref|NP_001001496.1|/2.9302e-138/gap junction alpha-6 protein [Mus musculus] 244550 2080 0.073333333 0.03 -1.289506617 Down 0.139521983 Podnl1 podocan-like 1 K08119|1|6e-28|128|cin:100178772|extracellular matrix protein 2 GO:0031012//extracellular matrix - - gi|160419223|sp|Q6P3Y9.2|PONL1_MOUSE/0/RecName: Full=Podocan-like protein 1; Flags: Precursor 242235 2046 0.03 0.07 1.222392421 Up 0.139521983 Lrit3 "leucine-rich repeat, immunoglobulin-like and transmembrane domains 3" K16357|1|1e-27|127|bfo:BRAFLDRAFT_84652|leucine-rich repeat and fibronectin type-III domain-containing protein 4;K20230|2|2e-25|120|pxy:105380848|kekkon-1;K07523|3|8e-25|118|api:100164134|netrin-G1 ligand;K19511|4|8e-25|118|bfo:BRAFLDRAFT_210822|peroxidase [EC:1.11.1.7];K16354|5|1e-24|117|bfo:BRAFLDRAFT_89096|leucine-rich repeat and fibronectin type-III domain-containing protein 1 - - - "gi|564473380|ref|NP_001274153.1|/0/leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 precursor [Mus musculus]" 75563 2086 0.03 0.07 1.222392421 Up 0.139521983 Dnali1 "dynein, axonemal, light intermediate polypeptide 1" "K10410|1|1e-133|479|cge:100754224|dynein light intermediate chain, axonemal" GO:0005875//microtubule associated complex - - gi|354480201|ref|XP_003502296.1|/8.60506e-133/PREDICTED: LOW QUALITY PROTEIN: axonemal dynein light intermediate polypeptide 1 [Cricetulus griseus] 545527 2195 0.073333333 0.03 -1.289506617 Down 0.139521983 Erich6 glutamate rich 6 - - - - gi|124486919|ref|NP_001074731.1|/0/glutamate-rich protein 6 [Mus musculus] 320858 4570 0.03 0.073333333 1.289506617 Up 0.139521983 L3mbtl4 l(3)mbt-like 4 (Drosophila) K11461|1|5e-46|189|tca:654967|polycomb protein SCMH1 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" gi|158198537|ref|NP_796252.2|/0/lethal(3)malignant brain tumor-like protein 4 [Mus musculus] 107831 6227 0.026666667 0.063333333 1.247927513 Up 0.139521983 Adgrb1 adhesion G protein-coupled receptor B1 K04596|1|0.0|2833|mmu:107831|brain-specific angiogenesis inhibitor 1 - - - - 381813 2413 0.063333333 0.026666667 -1.247927513 Down 0.139521983 Prmt8 protein arginine N-methyltransferase 8 K11439|1|0.0|716|cge:100770963|type I protein arginine methyltransferase [EC:2.1.1.319] GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0016274//protein-arginine N-methyltransferase activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity GO:0035247//peptidyl-arginine omega-N-methylation;GO:0051098//regulation of binding;GO:0016571//histone methylation gi|357527369|ref|NP_958759.2|/0/protein arginine N-methyltransferase 8 [Mus musculus] 16069 2111 0.03 0.073333333 1.289506617 Up 0.139521983 Jchain immunoglobulin joining chain - - - - - 226548 3178.54 46.91333333 48.06 0.034838636 Up 0.139456166 Aph1a "aph1 homolog A, gamma secretase subunit" K06172|1|1e-132|443|bacu:102999717|anterior pharynx defective 1 - - - - 66070 1152 49.92666667 51.08 0.032947936 Up 0.139456166 Cwc15 CWC15 spliceosome-associated protein K12863|1|4e-72|274|hgl:101714226|protein CWC15 - - - - 109889 3313 0.173333333 0.123333333 -0.490986353 Down 0.139437361 Mzf1 myeloid zinc finger 1 K09221|1|0.0|1353|rno:361508|myeloid zinc finger protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0000975//regulatory region DNA binding;GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0000975//regulatory region DNA binding;GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0000975//regulatory region DNA binding;GO:0042802//identical protein binding "GO:0044764;GO:0006351//transcription, DNA-templated;GO:0044764;GO:0006351//transcription, DNA-templated;GO:0044764;GO:0006351//transcription, DNA-templated" "gi|148706125|gb|EDL38072.1|/0/myeloid zinc finger 1, isoform CRA_c, partial [Mus musculus]" 432720 1242 0.163333333 0.116666667 -0.485426827 Down 0.139437361 Akr1c19 "aldo-keto reductase family 1, member C19" K04119|1|7e-150|532|ngi:103725887|aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357];K00212|3|2e-139|497|mcc:711198|20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20];K13374|5|1e-138|495|mmu:27384|aldo-keto reductase family 1 member C13 [EC:1.1.1.218] - - - "gi|282398141|ref|NP_001013807.2|/0/aldo-keto reductase family 1, member C19 [Mus musculus]" 109660 919 0.163333333 0.116666667 -0.485426827 Down 0.139437361 Ctrl chymotrypsin-like K09632|1|2e-135|484|mmu:109660|chymotrypsin-like protease [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|13374559|ref|NP_075671.1|/1.40303e-134/chymotrypsin-like protease CTRL-1 precursor [Mus musculus] 100048534 5947 0.123333333 0.173333333 0.490986353 Up 0.139437361 Cfap43 cilia and flagella associated protein 43 K16770|1|6e-07|60.5|aml:100464726|centriolin;K10388|3|3e-06|58.2|ola:101160251|plectin - - - gi|307344688|ref|NP_081835.2|/0/cilia- and flagella-associated protein 43 [Mus musculus] 21926 1605 0.123333333 0.173333333 0.490986353 Up 0.139437361 Tnf tumor necrosis factor "K03156|1|6e-121|437|mmu:21926|tumor necrosis factor superfamily, member 2" - - - - 243529 1126 1.546666667 1.656666667 0.099121046 Up 0.139399752 H1fx "H1 histone family, member X" K11275|1|1e-56|222|mmu:243529|histone H1/5 - - - - 106338 1344 1.593333333 1.706666667 0.099133192 Up 0.139399752 Nsun3 NOL1/NOP2/Sun domain family member 3 K14835|1|9e-18|94.0|tsp:Tsp_05558|ribosomal RNA methyltransferase Nop2 [EC:2.1.1.-] - GO:0016741 GO:0008152//metabolic process gi|116138396|gb|AAI25629.1|/0/NOL1/NOP2/Sun domain family member 3 [Mus musculus] 192786 8090.56 1.766666667 1.653333333 -0.095652239 Down 0.139399752 Rapgef6 Rap guanine nucleotide exchange factor (GEF) 6 K08020|1|0.0|730|mmu:192786|Rap guanine nucleotide exchange factor 6 GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0031267//small GTPase binding;GO:0031267//small GTPase binding;GO:0031267//small GTPase binding - gi|357394770|ref|NP_001239423.1|/0/rap guanine nucleotide exchange factor 6 isoform 1 [Mus musculus] 15357 4444 1.643333333 1.536666667 -0.096820896 Down 0.139399752 Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase K00021|1|0.0|1693|mmu:15357|hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34] GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0044439 "GO:0048037//cofactor binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0042802//identical protein binding;GO:0043168//anion binding" GO:0043405//regulation of MAP kinase activity;GO:0008284//positive regulation of cell proliferation;GO:0042692//muscle cell differentiation;GO:0032102;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0042311//vasodilation;GO:0031667//response to nutrient levels;GO:0008203//cholesterol metabolic process;GO:0043410//positive regulation of MAPK cascade;GO:0016114//terpenoid biosynthetic process;GO:0032872//regulation of stress-activated MAPK cascade;GO:0006733;GO:0007632//visual behavior;GO:0010659//cardiac muscle cell apoptotic process;GO:0051259//protein oligomerization;GO:0006694//steroid biosynthetic process;GO:0007519//skeletal muscle tissue development;GO:0097305//response to alcohol;GO:0010656//negative regulation of muscle cell apoptotic process gi|568984222|ref|XP_006517593.1|/0/PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform X2 [Mus musculus] 105387 2459 1.686666667 1.573333333 -0.100350525 Down 0.139399752 Akr1c14 "aldo-keto reductase family 1, member C14" K04119|1|7e-139|497|ecb:100070616|aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357];K00212|4|8e-135|483|mcc:711198|20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:1.1.1.149 1.1.1.357 1.3.1.20] - GO:0047023//androsterone dehydrogenase activity GO:0006629//lipid metabolic process;GO:0021543//pallium development gi|19527294|ref|NP_598833.1|/0/3-alpha-hydroxysteroid dehydrogenase [Mus musculus] 13430 3351.11 48.17666667 47.04333333 -0.034344289 Down 0.139380947 Dnm2 dynamin 2 K01528|1|0.0|1488|mmu:13430|dynamin GTPase [EC:3.6.5.5] GO:0032991//macromolecular complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0015630//microtubule cytoskeleton;GO:0030139//endocytic vesicle;GO:0012505//endomembrane system;GO:0032991//macromolecular complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0015630//microtubule cytoskeleton;GO:0030139//endocytic vesicle;GO:0012505//endomembrane system;GO:0032991//macromolecular complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0015630//microtubule cytoskeleton;GO:0030139//endocytic vesicle;GO:0012505//endomembrane system GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008289//lipid binding;GO:0019900//kinase binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008289//lipid binding;GO:0019900//kinase binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008289//lipid binding;GO:0019900//kinase binding GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0009154//purine ribonucleotide catabolic process;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0009154//purine ribonucleotide catabolic process;GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport;GO:0009154//purine ribonucleotide catabolic process gi|359751399|ref|NP_001240823.1|/0/dynamin-2 isoform 4 [Mus musculus] 53333 1576.3 59.57666667 60.69333333 0.02679065 Up 0.139305728 Tomm40 translocase of outer mitochondrial membrane 40 homolog (yeast) K11518|1|2e-159|565|mmu:53333|mitochondrial import receptor subunit TOM40 GO:0031306//intrinsic component of mitochondrial outer membrane;GO:0031301//integral component of organelle membrane;GO:0031306//intrinsic component of mitochondrial outer membrane;GO:0031301//integral component of organelle membrane GO:0008565//protein transporter activity;GO:0022829//wide pore channel activity;GO:0005244//voltage-gated ion channel activity;GO:0008565//protein transporter activity;GO:0022829//wide pore channel activity;GO:0005244//voltage-gated ion channel activity GO:0006820//anion transport;GO:0006605//protein targeting;GO:0019538//protein metabolic process;GO:0006820//anion transport;GO:0006605//protein targeting;GO:0019538//protein metabolic process gi|6650562|gb|AAF21906.1|AF109918_1/1.49988e-161/mitochondrial outer membrane protein MOM35 [Mus musculus] 208292 10857 2.016666667 1.9 -0.085973223 Down 0.139277521 Zfp871 zinc finger protein 871 K09228|1|0.0|1252|mmu:208292|KRAB domain-containing zinc finger protein - - - gi|28972890|dbj|BAC65861.1|/0/mKIAA3006 protein [Mus musculus] 21975 3740 1.843333333 1.966666667 0.093435474 Up 0.139277521 Top3a topoisomerase (DNA) III alpha K03165|1|0.0|1966|mmu:21975|DNA topoisomerase III [EC:5.99.1.2] GO:0016604//nuclear body;GO:0043232 GO:0032550;GO:0046914//transition metal ion binding;GO:0003916//DNA topoisomerase activity GO:0071103//DNA conformation change gi|6678403|ref|NP_033436.1|/0/DNA topoisomerase 3-alpha [Mus musculus] 434178 3760 1.9 2.023333333 0.090734597 Up 0.139277521 Zfp141 zinc finger protein 141 K09228|1|0.0|1428|mmu:434178|KRAB domain-containing zinc finger protein - GO:0043169//cation binding;GO:0043169//cation binding - gi|823683790|ref|NP_001296317.1|/0/zinc finger protein 141 isoform 1 [Mus musculus] 70691 1020 0.353333333 0.29 -0.284976959 Down 0.139268118 3830403N18Rik RIKEN cDNA 3830403N18 gene K19528|1|9e-38|159|mmu:20962|synaptonemal complex protein 3 - - - gi|21746153|ref|NP_081786.1|/1.86703e-117/Xlr-like [Mus musculus] 106877 3403 46.64666667 47.74333333 0.033525305 Up 0.139230509 Afap1l1 actin filament associated protein 1-like 1 K18616|1|2e-149|533|bta:534032|actin filament associated protein 1 GO:0019866//organelle inner membrane;GO:0044429;GO:0042995//cell projection GO:0042802//identical protein binding;GO:0008289//lipid binding GO:0044267//cellular protein metabolic process gi|31982370|ref|NP_849259.2|/0/actin filament-associated protein 1-like 1 [Mus musculus] 78785 3808.9 59.75333333 60.84666667 0.026159035 Up 0.139202302 Clip4 "CAP-GLY domain containing linker protein family, member 4" K10423|1|0.0|791|mmu:78785|CAP-Gly domain-containing linker protein 3/4 - - - gi|407892487|ref|NP_001258413.1|/0/CAP-Gly domain-containing linker protein 4 isoform 4 [Mus musculus] 229211 3913 13.24666667 13.58666667 0.036562179 Up 0.139183497 Acad9 "acyl-Coenzyme A dehydrogenase family, member 9" K15980|1|0.0|1197|mmu:229211|acyl-CoA dehydrogenase family member 9 [EC:1.3.99.-] GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle GO:0016491//oxidoreductase activity;GO:0000166//nucleotide binding GO:0044710 "gi|100817933|ref|NP_766266.3|/0/acyl-CoA dehydrogenase family member 9, mitochondrial [Mus musculus]" 22041 2332 13 13.33666667 0.036886505 Up 0.139183497 Trf transferrin K14736|1|0.0|1431|mmu:22041|transferrin - - - - 208606 2192 11.62 11.95666667 0.041205176 Up 0.139183497 Rsrc2 arginine/serine-rich coiled-coil 2 - - - - gi|62078991|ref|NP_001014150.1|/9.28214e-77/arginine/serine-rich coiled-coil protein 2 [Rattus norvegicus] 12151 3594 13.34333333 13.68333333 0.036300606 Up 0.139183497 Bmi1 Bmi1 polycomb ring finger oncogene K11459|1|4e-169|598|phi:102104382|polycomb group RING finger protein 4 GO:0044451;GO:0031519//PcG protein complex GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0019787//ubiquitin-like protein transferase activity GO:0001501//skeletal system development;GO:0033080//immature T cell proliferation in thymus;GO:0017145//stem cell division;GO:0006366//transcription from RNA polymerase II promoter;GO:0007417//central nervous system development;GO:0016570//histone modification;GO:0048562//embryonic organ morphogenesis;GO:0031398//positive regulation of protein ubiquitination;GO:0006955//immune response;GO:0006915//apoptotic process;GO:0030888//regulation of B cell proliferation;GO:0043009//chordate embryonic development;GO:0008284//positive regulation of cell proliferation;GO:0009952//anterior/posterior pattern specification gi|929428759|ref|XP_005480372.2|/2.40153e-168/PREDICTED: polycomb complex protein BMI-1 [Zonotrichia albicollis] 12313 4140 61.92333333 60.85333333 -0.025146843 Down 0.13911768 Calm1 calmodulin 1 K02183|1|9e-79|298|shr:100935134|calmodulin - - - - 59043 2438 45.94333333 47.01 0.033112148 Up 0.13911768 Wsb2 WD repeat and SOCS box-containing 2 K10342|1|0.0|813|mmu:59043|WD repeat and SOCS box-containing protein 2 - - GO:0007165//signal transduction gi|31982686|ref|NP_067514.2|/0/WD repeat and SOCS box-containing protein 2 [Mus musculus] 381853 1792 0.036666667 0.076666667 1.064130337 Up 0.139080071 Gipr gastric inhibitory polypeptide receptor K04580|1|0.0|824|mmu:381853|gastric inhibitory polypeptide receptor GO:0031224//intrinsic component of membrane GO:0004930//G-protein coupled receptor activity;GO:0042277//peptide binding GO:0007186//G-protein coupled receptor signaling pathway;GO:0009611//response to wounding;GO:0031016//pancreas development;GO:0050796//regulation of insulin secretion;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0006171//cAMP biosynthetic process;GO:0010038//response to metal ion;GO:0009746;GO:0033993//response to lipid gi|124249103|ref|NP_001074284.1|/0/gastric inhibitory polypeptide receptor precursor [Mus musculus] 211652 3315 0.033333333 0.073333333 1.137503524 Up 0.139080071 Wwc1 "WW, C2 and coiled-coil domain containing 1" K16685|1|0.0|1781|mmu:211652|protein KIBRA GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0001726//ruffle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0003712//transcription cofactor activity;GO:0005515//protein binding "GO:0048870//cell motility;GO:0009966//regulation of signal transduction;GO:0006351//transcription, DNA-templated;GO:0000165//MAPK cascade" gi|82524278|ref|NP_740749.1|/0/protein KIBRA [Mus musculus] 83561 4887 0.03 0.066666667 1.152003093 Up 0.139080071 Tdrd1 tudor domain containing 1 K18405|1|0.0|2226|mmu:83561|tudor domain-containing protein 1/4/6/7 GO:0043186//P granule;GO:0043186//P granule;GO:0043186//P granule;GO:0043186//P granule GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0048869//cellular developmental process;GO:0016458//gene silencing;GO:0022403;GO:0048232//male gamete generation;GO:0034660//ncRNA metabolic process;GO:0003006//developmental process involved in reproduction;GO:0006306//DNA methylation;GO:0048869//cellular developmental process;GO:0016458//gene silencing;GO:0022403;GO:0048232//male gamete generation;GO:0034660//ncRNA metabolic process;GO:0003006//developmental process involved in reproduction;GO:0006306//DNA methylation;GO:0048869//cellular developmental process;GO:0016458//gene silencing;GO:0022403;GO:0048232//male gamete generation;GO:0034660//ncRNA metabolic process;GO:0003006//developmental process involved in reproduction;GO:0006306//DNA methylation;GO:0048869//cellular developmental process;GO:0016458//gene silencing;GO:0022403;GO:0048232//male gamete generation;GO:0034660//ncRNA metabolic process;GO:0003006//developmental process involved in reproduction;GO:0006306//DNA methylation gi|50355696|ref|NP_001002238.1|/0/tudor domain-containing protein 1 [Mus musculus] 239250 4243 0.03 0.066666667 1.152003093 Up 0.139080071 Slitrk6 "SLIT and NTRK-like family, member 6" K06838|1|3e-31|140|xla:380270|slit 1;K06850|3|3e-30|137|mdo:100030923|slit 3 GO:0031224//intrinsic component of membrane - GO:0048667//cell morphogenesis involved in neuron differentiation gi|30425254|ref|NP_780708.1|/0/SLIT and NTRK-like protein 6 precursor [Mus musculus] 403202 2115 0.03 0.066666667 1.152003093 Up 0.139080071 A430093F15Rik RIKEN cDNA A430093F15 gene - - - - "gi|148709434|gb|EDL41380.1|/1.62329e-62/RIKEN cDNA A430093F15, isoform CRA_b, partial [Mus musculus]" 319750 1516.93 0.033333333 0.07 1.070389328 Up 0.139080071 A230009B12Rik RIKEN cDNA A230009B12 gene - - - - "gi|148670134|gb|EDL02081.1|/8.60847e-69/mCG144945, isoform CRA_a, partial [Mus musculus]" 192120 1743 0.036666667 0.076666667 1.064130337 Up 0.139080071 Bspry B-box and SPRY domain containing K12015|1|2e-19|99.8|gja:107114552|tripartite motif-containing protein 39 [EC:2.3.2.27];K12004|3|3e-18|96.3|mdo:100010477|tripartite motif-containing protein 14 GO:0005924//cell-substrate adherens junction;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding GO:0070838//divalent metal ion transport gi|20149730|ref|NP_619594.1|/0/B box and SPRY domain-containing protein [Mus musculus] 23829 1260 0.083333333 0.04 -1.058893689 Down 0.139080071 C1ql1 "complement component 1, q subcomponent-like 1" K18744|1|2e-16|89.7|dre:407729|caprin-2 GO:0005576//extracellular region;GO:0044424 - GO:0044708//single-organism behavior gi|226874911|ref|NP_035925.2|/2.43102e-99/C1q-related factor precursor [Mus musculus] 13386 4054 0.036666667 0.076666667 1.064130337 Up 0.139080071 Dlk1 delta-like 1 homolog (Drosophila) K06051|1|2e-58|231|dre:30120|delta GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0007219//Notch signaling pathway;GO:0001501//skeletal system development;GO:0048869//cellular developmental process;GO:0007219//Notch signaling pathway;GO:0001501//skeletal system development;GO:0048869//cellular developmental process;GO:0007219//Notch signaling pathway;GO:0001501//skeletal system development;GO:0048869//cellular developmental process;GO:0007219//Notch signaling pathway;GO:0001501//skeletal system development;GO:0048869//cellular developmental process;GO:0007219//Notch signaling pathway;GO:0001501//skeletal system development;GO:0048869//cellular developmental process gi|299758514|ref|NP_001177634.1|/0/protein delta homolog 1 isoform 4 precursor [Mus musculus] 18392 3027 0.04 0.08 1 Up 0.139080071 Orc1 "origin recognition complex, subunit 1" K02603|1|0.0|1562|mmu:18392|origin recognition complex subunit 1 GO:0000808//origin recognition complex;GO:0031981//nuclear lumen;GO:0016020//membrane GO:0032550;GO:0003676//nucleic acid binding;GO:0016462//pyrophosphatase activity GO:0006259//DNA metabolic process gi|158517935|ref|NP_035145.2|/0/origin recognition complex subunit 1 [Mus musculus] 232345 4687 0.03 0.066666667 1.152003093 Up 0.139080071 A2m alpha-2-macroglobulin K03910|1|0.0|2834|mmu:232345|alpha-2-macroglobulin GO:0031988//membrane-bounded vesicle;GO:0044421 GO:0004866//endopeptidase inhibitor activity;GO:0019958//C-X-C chemokine binding;GO:0019838//growth factor binding GO:0002526//acute inflammatory response;GO:0031667//response to nutrient levels;GO:0010466//negative regulation of peptidase activity;GO:0030154//cell differentiation;GO:0031960//response to corticosteroid gi|148277039|ref|NP_783327.2|/0/alpha-2-macroglobulin-P precursor [Mus musculus] 100038743 1347 0.08 0.036666667 -1.125530882 Down 0.139080071 Gm13629 predicted gene 13629 K04841|1|3e-17|92.0|pale:102894519|voltage-gated sodium channel type IX alpha - - - "gi|148695065|gb|EDL27012.1|/2.82377e-32/mCG145435, partial [Mus musculus]" 381157 8421 0.076666667 0.036666667 -1.064130337 Down 0.139080071 Greb1l growth regulation by estrogen in breast cancer-like - GO:0031224//intrinsic component of membrane - - gi|134947988|ref|NP_001077097.1|/0/GREB1-like protein [Mus musculus] 83395 3375 0.043333333 0.086666667 1 Up 0.139080071 Sp6 trans-acting transcription factor 6 K09196|1|0.0|693|mmu:83395|transcription factor Sp6 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0042476//odontogenesis;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter gi|402899442|ref|XP_003912706.1|/0/PREDICTED: transcription factor Sp6 isoform X1 [Papio anubis] 15168 3268 0.043333333 0.086666667 1 Up 0.139080071 Hcn3 "hyperpolarization-activated, cyclic nucleotide-gated K+ 3" K04956|1|0.0|1342|mmu:15168|hyperpolarization activated cyclic nucleotide-gated potassium channel 3 GO:0031224//intrinsic component of membrane GO:0030551//cyclic nucleotide binding;GO:0005267//potassium channel activity GO:0006814//sodium ion transport;GO:0034220//ion transmembrane transport gi|6680191|ref|NP_032253.1|/0/potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 [Mus musculus] 320923 2795 0.036666667 0.076666667 1.064130337 Up 0.139080071 Mtap7d3 MAP7 domain containing 3 K16807|1|0.0|1459|mmu:320923|MAP7 domain-containing protein 3 GO:0043232 - - gi|569010252|ref|XP_006528152.1|/0/PREDICTED: MAP7 domain-containing protein 3 isoform X2 [Mus musculus] 71125 1262 0.083333333 0.04 -1.058893689 Down 0.139080071 4933407G14Rik RIKEN cDNA 4933407G14 gene - - - - "gi|148699975|gb|EDL31922.1|/5.68296e-48/mCG146288, partial [Mus musculus]" 75770 4047 0.03 0.066666667 1.152003093 Up 0.139080071 Brsk2 BR serine/threonine kinase 2 K08796|1|0.0|1215|mmu:75770|BR serine/threonine kinase [EC:2.7.11.1] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0019900//kinase binding;GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0019900//kinase binding;GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0019900//kinase binding;GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0019900//kinase binding GO:0007163//establishment or maintenance of cell polarity;GO:0044772//mitotic cell cycle phase transition;GO:0012501//programmed cell death;GO:0050796//regulation of insulin secretion;GO:0031175//neuron projection development;GO:0030036//actin cytoskeleton organization;GO:0016192//vesicle-mediated transport;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006468//protein phosphorylation;GO:0034976//response to endoplasmic reticulum stress;GO:0000087//mitotic M phase;GO:0007163//establishment or maintenance of cell polarity;GO:0044772//mitotic cell cycle phase transition;GO:0050796//regulation of insulin secretion;GO:0030036//actin cytoskeleton organization;GO:0016192//vesicle-mediated transport;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006468//protein phosphorylation;GO:0034976//response to endoplasmic reticulum stress;GO:0000087//mitotic M phase;GO:0007163//establishment or maintenance of cell polarity;GO:0044772//mitotic cell cycle phase transition;GO:0012501//programmed cell death;GO:0050796//regulation of insulin secretion;GO:0031175//neuron projection development;GO:0030036//actin cytoskeleton organization;GO:0016192//vesicle-mediated transport;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006468//protein phosphorylation;GO:0034976//response to endoplasmic reticulum stress;GO:0000087//mitotic M phase;GO:0007163//establishment or maintenance of cell polarity;GO:0012501//programmed cell death;GO:0050796//regulation of insulin secretion;GO:0031175//neuron projection development;GO:0030036//actin cytoskeleton organization;GO:0016192//vesicle-mediated transport;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006468//protein phosphorylation;GO:0034976//response to endoplasmic reticulum stress;GO:0000087//mitotic M phase gi|454523099|ref|NP_001263692.1|/0/serine/threonine-protein kinase BRSK2 isoform delta [Mus musculus] 73748 3652 0.073333333 0.036666667 -1 Down 0.139080071 Gadl1 glutamate decarboxylase-like 1 K18966|1|0.0|1002|mmu:73748|sulfinoalanine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.29 4.1.1.11] - GO:0043168//anion binding;GO:0016830//carbon-carbon lyase activity GO:0043436 gi|221222529|sp|Q80WP8.3|GADL1_MOUSE/0/RecName: Full=Acidic amino acid decarboxylase GADL1; AltName: Full=Aspartate 1-decarboxylase; Short=ADC; AltName: Full=Cysteine sulfinic acid decarboxylase; Short=CSADC; AltName: Full=Glutamate decarboxylase-like protein 1 20980 3386 0.03 0.066666667 1.152003093 Up 0.139080071 Syt2 synaptotagmin II K19902|1|0.0|651|mmu:20980|synaptotagmin-2 GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle;GO:0030667//secretory granule membrane GO:0046872//metal ion binding;GO:0000149//SNARE binding;GO:0005543//phospholipid binding GO:0006887//exocytosis gi|31543797|ref|NP_033333.2|/0/synaptotagmin-2 [Mus musculus] 230777 2176 0.03 0.066666667 1.152003093 Up 0.139080071 Hcrtr1 hypocretin (orexin) receptor 1 K04238|1|0.0|808|mmu:230777|hypocretin (orexin) receptor 1 GO:0031224//intrinsic component of membrane GO:0008528//G-protein coupled peptide receptor activity;GO:0042277//peptide binding GO:0007186//G-protein coupled receptor signaling pathway;GO:0007610//behavior gi|251823830|ref|NP_945197.2|/0/orexin receptor type 1 isoform 1 [Mus musculus] 11705 1665 0.036666667 0.08 1.125530882 Up 0.139080071 Amh anti-Mullerian hormone K04665|1|0.0|888|mmu:11705|anti-mullerian hormone GO:0044424;GO:0044421 GO:0005126//cytokine receptor binding GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0001541//ovarian follicle development;GO:0007154//cell communication;GO:0010033//response to organic substance gi|85861194|ref|NP_031471.2|/0/muellerian-inhibiting factor precursor [Mus musculus] 320463 7333 0.036666667 0.073333333 1 Up 0.139080071 F630111L10Rik RIKEN cDNA F630111L10 gene - - - - gi|74221130|dbj|BAE42067.1|/1.15806e-42/unnamed protein product [Mus musculus] 240843 4117 0.073333333 0.033333333 -1.137503524 Down 0.139080071 Brinp2 bone morphogenic protein/retinoic acid inducible neural-specific 2 - GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body - GO:0048731//system development;GO:0051726//regulation of cell cycle gi|28972830|dbj|BAC65831.1|/0/mKIAA1747 protein [Mus musculus] 223650 21627 0.07 0.033333333 -1.070389328 Down 0.139080071 Eppk1 epiplakin 1 K10388|1|0.0|1303|cmk:103179737|plectin GO:0043232 - - gi|37537522|ref|NP_659097.2|/0/epiplakin [Mus musculus] 110958 2051 0.03 0.066666667 1.152003093 Up 0.139080071 M1ap meiosis 1 associated protein - GO:0031224//intrinsic component of membrane - GO:0006333//chromatin assembly or disassembly;GO:0010467//gene expression gi|188035879|ref|NP_149070.2|/0/meiosis 1 arrest protein [Mus musculus] 239337 6234 0.07 0.033333333 -1.070389328 Down 0.139080071 Adamts12 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12" K08626|1|0.0|3296|mmu:239337|a disintegrin and metalloproteinase with thrombospondin motifs 12 [EC:3.4.24.-] - - - gi|153945812|ref|NP_780710.2|/0/A disintegrin and metalloproteinase with thrombospondin motifs 12 precursor [Mus musculus] 219149 2555 0.083333333 0.04 -1.058893689 Down 0.139080071 Xkr6 X-linked Kx blood group related 6 K01128|1|9e-34|148|clv:102091645|sphingomyelin phosphodiesterase acid-like 3 [EC:3.1.4.-];K19522|2|2e-14|84.3|cge:100762544|membrane transport protein XK GO:0031224//intrinsic component of membrane - - gi|58865652|ref|NP_001012042.1|/0/XK-related protein 6 [Rattus norvegicus] 30785 5931 0.036666667 0.08 1.125530882 Up 0.139080071 Cttnbp2 cortactin binding protein 2 K10380|1|2e-24|118|cjo:107313591|ankyrin GO:0005856//cytoskeleton;GO:0030136//clathrin-coated vesicle GO:0019904//protein domain specific binding GO:0007417//central nervous system development;GO:0007010//cytoskeleton organization gi|91982738|ref|NP_525024.1|/0/cortactin-binding protein 2 [Mus musculus] 74121 2876 0.036666667 0.076666667 1.064130337 Up 0.139080071 Acoxl acyl-Coenzyme A oxidase-like K00232|1|4e-72|275|dre:406421|acyl-CoA oxidase [EC:1.3.3.6] GO:0042579//microbody "GO:0016634//oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor;GO:0000166//nucleotide binding" GO:0009062//fatty acid catabolic process gi|21311885|ref|NP_083041.1|/0/acyl-coenzyme A oxidase-like protein [Mus musculus] 170745 3498 0.03 0.066666667 1.152003093 Up 0.139080071 Xpnpep2 "X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound" K14208|1|0.0|1495|mmu:170745|Xaa-Pro aminopeptidase 2 [EC:3.4.11.9] - GO:0043169//cation binding;GO:0008238//exopeptidase activity;GO:0043169//cation binding;GO:0008238//exopeptidase activity - gi|26347533|dbj|BAC37415.1|/0/unnamed protein product [Mus musculus] 17388 4335 49.81333333 50.87333333 0.030377672 Up 0.139061266 Mmp15 matrix metallopeptidase 15 K07995|1|0.0|1149|mmu:17388|matrix metalloproteinase-15 (membrane-inserted) [EC:3.4.24.-] GO:0031224//intrinsic component of membrane "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0043627//response to estrogen gi|6678900|ref|NP_032635.1|/0/matrix metalloproteinase-15 preproprotein [Mus musculus] 56737 3062 2.42 2.29 -0.079659449 Down 0.139023656 Alg2 "asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase)" "K03843|1|0.0|848|mmu:56737|alpha-1,3/alpha-1,6-mannosyltransferase [EC:2.4.1.132 2.4.1.257]" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part "GO:0046983//protein dimerization activity;GO:0000009//alpha-1,6-mannosyltransferase activity;GO:0004376//glycolipid mannosyltransferase activity" GO:0006486//protein glycosylation;GO:0010038//response to metal ion "gi|172072657|ref|NP_064382.3|/0/alpha-1,3/1,6-mannosyltransferase ALG2 [Mus musculus]" 320982 3967 2.343333333 2.21 -0.084515819 Down 0.139023656 Arl4c ADP-ribosylation factor-like 4C K07945|1|5e-117|422|ggo:101151990|ADP-ribosylation factor-like protein 4 GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0015631//tubulin binding GO:0016192//vesicle-mediated transport;GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process "gi|29436760|gb|AAH49804.1|/7.35189e-134/Arl4c protein, partial [Mus musculus]" 435684 1564 2.173333333 2.303333333 0.083813746 Up 0.139023656 Shf Src homology 2 domain containing F K19862|1|3e-11|72.8|hmg:100201881|NCK adaptor protein 2;K07365|2|4e-11|72.0|ssc:100192438|NCK adaptor protein 1 - - - gi|755500175|ref|XP_006499940.2|/6.08532e-154/PREDICTED: SH2 domain-containing adapter protein F isoform X2 [Mus musculus] 52710 2700 2.353333333 2.223333333 -0.081981422 Down 0.139023656 Slc52a2 "solute carrier protein 52, member 2" K14620|1|6e-60|235|pbi:103065456|riboflavin transporter 2 GO:0016021//integral component of membrane GO:0051183//vitamin transporter activity GO:0015711//organic anion transport "gi|21313230|ref|NP_083919.1|/5.19037e-173/solute carrier family 52, riboflavin transporter, member 2 precursor [Mus musculus]" 18113 1013 2.596666667 2.463333333 -0.076048964 Down 0.139023656 Nnmt nicotinamide N-methyltransferase K00541|1|2e-152|540|mmu:18113|nicotinamide N-methyltransferase [EC:2.1.1.1] - - - gi|6754866|ref|NP_035054.1|/1.49786e-151/nicotinamide N-methyltransferase isoform 1 [Mus musculus] 229700 3270 2.463333333 2.333333333 -0.078219442 Down 0.139023656 Rbm15 RNA binding motif protein 15 K13190|1|0.0|1363|mmu:229700|RNA-binding protein 15 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0001525//angiogenesis;GO:0007219//Notch signaling pathway;GO:0030099//myeloid cell differentiation;GO:0003281//ventricular septum development gi|111308226|gb|AAI20591.1|/0/RNA binding motif protein 15 [Mus musculus] 56457 4147 45.18 44.14 -0.033597641 Down 0.138939035 Clptm1 cleft lip and palate associated transmembrane protein 1 - GO:0009986//cell surface;GO:0031224//intrinsic component of membrane - GO:0033077//T cell differentiation in thymus gi|103472025|ref|NP_062623.2|/0/cleft lip and palate transmembrane protein 1 homolog [Mus musculus] 268510 4277 0.126666667 0.176666667 0.479992941 Up 0.13892023 Mgat5b "mannoside acetylglucosaminyltransferase 5, isoenzyme B" "K09661|1|0.0|1644|mmu:268510|mannosyl alpha-1,6-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B [EC:2.4.1.-]" - - - - 20873 3563.05 0.313333333 0.376666667 0.265590111 Up 0.138901425 Plk4 polo-like kinase 4 K08863|1|0.0|1694|mmu:20873|polo-like kinase 4 [EC:2.7.11.21] GO:0031981//nuclear lumen;GO:0005813//centrosome;GO:0031981//nuclear lumen;GO:0005813//centrosome;GO:0031981//nuclear lumen;GO:0005813//centrosome GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity GO:0060706//cell differentiation involved in embryonic placenta development;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007099//centriole replication;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007099//centriole replication;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007099//centriole replication "gi|148703197|gb|EDL35144.1|/0/mCG142332, isoform CRA_d, partial [Mus musculus]" 236312 3497 0.35 0.29 -0.271302022 Down 0.138901425 Pyhin1 "pyrin and HIN domain family, member 1" K12966|1|3e-42|177|pps:100976265|absent in melanoma 2 GO:0043231//intracellular membrane-bounded organelle - GO:0035456//response to interferon-beta gi|27923921|ref|NP_778191.1|/0/pyrin and HIN domain-containing protein 1 [Mus musculus] 15442 3082 0.333333333 0.276666667 -0.268816758 Down 0.138901425 Hpse heparanase K07964|1|0.0|1015|mmu:15442|heparanase 1 [EC:3.2.1.166] GO:0005764//lysosome;GO:0044425;GO:0031012//extracellular matrix "GO:0005515//protein binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds" GO:0060055//angiogenesis involved in wound healing;GO:0001942//hair follicle development;GO:0001819//positive regulation of cytokine production;GO:0008284//positive regulation of cell proliferation;GO:0007596//blood coagulation;GO:0031589//cell-substrate adhesion;GO:0030167//proteoglycan catabolic process "gi|148688334|gb|EDL20281.1|/0/heparanase, isoform CRA_a, partial [Mus musculus]" 66836 748 50.31 51.34333333 0.029331773 Up 0.138892023 Tmem223 transmembrane protein 223 K14284|1|9e-27|122|fpg:101920344|nuclear RNA export factor;K03131|3|7e-17|79.0|ggo:101134630|transcription initiation factor TFIID subunit 6 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|13385262|ref|NP_080067.1|/1.39189e-109/transmembrane protein 223 [Mus musculus] 19752 977 0.456666667 0.53 0.214850872 Up 0.138788597 Rnase1 "ribonuclease, RNase A family, 1 (pancreatic)" K01168|1|4e-78|293|mmu:19752|pancreatic ribonuclease [EC:3.1.27.5] - "GO:0016892//endoribonuclease activity, producing 3'-phosphomonoesters;GO:0097159//organic cyclic compound binding" GO:0090304 gi|573014574|tpe|CDG32019.1|/1.8115e-82/TPA: ribonuclease A c1 [Mus musculus] 668272 1768 0.45 0.52 0.208586622 Up 0.138788597 Gm9079 transmembrane emp24 domain trafficking protein 2 pseudogene K20347|1|7e-46|136|tup:102470406|p24 family protein beta-1 GO:0000139//Golgi membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0031224//intrinsic component of membrane;GO:0030667//secretory granule membrane;GO:0030137//COPI-coated vesicle GO:0005488//binding GO:0043087//regulation of GTPase activity;GO:0014020;GO:0010467//gene expression;GO:0040007//growth;GO:0006901//vesicle coating;GO:0016482//cytosolic transport;GO:0006612//protein targeting to membrane;GO:0035964//COPI-coated vesicle budding;GO:0001890//placenta development;GO:0003143//embryonic heart tube morphogenesis;GO:0000578//embryonic axis specification;GO:0009952//anterior/posterior pattern specification;GO:0001701//in utero embryonic development gi|947231308|ref|XP_014443550.1|/5.5858e-45/PREDICTED: transmembrane emp24 domain-containing protein 2 [Tupaia chinensis] 12663 6117 0.493333333 0.426666667 -0.209453366 Down 0.138788597 Chml choroideremia-like K17255|1|2e-30|138|smm:Smp_024520|Rab GDP dissociation inhibitor - - - - 19714 10666 0.516666667 0.446666667 -0.210035215 Down 0.138788597 Rev3l "REV3 like, DNA directed polymerase zeta catalytic subunit" K02350|1|0.0|5984|mmu:19714|DNA polymerase zeta [EC:2.7.7.7] - - - gi|153792337|ref|NP_035394.2|/0/DNA polymerase zeta catalytic subunit [Mus musculus] 19249 8298 0.54 0.466666667 -0.210566986 Down 0.138788597 Ptpn13 "protein tyrosine phosphatase, non-receptor type 13" K02374|1|0.0|4539|mmu:19249|tyrosine-protein phosphatase non-receptor type 13 GO:0043232;GO:0031252//cell leading edge;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0042995//cell projection GO:0005488//binding;GO:0004721//phosphoprotein phosphatase activity GO:0006470//protein dephosphorylation gi|134948762|ref|NP_035334.2|/0/tyrosine-protein phosphatase non-receptor type 13 [Mus musculus] 74666 2389 0.143333333 0.196666667 0.456378295 Up 0.138769792 4930432K21Rik RIKEN cDNA 4930432K21 gene - - - - gi|255522947|ref|NP_083321.2|/0/uncharacterized protein C19orf57 homolog isoform 1 [Mus musculus] 628779 2894 0.123333333 0.17 0.462971976 Up 0.138769792 Hs3st4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 K09678|1|0.0|737|mmu:628779|[heparan sulfate]-glucosamine 3-sulfotransferase 4 [EC:2.8.2.-] - - - gi|354983489|ref|NP_001239001.1|/0/heparan sulfate glucosamine 3-O-sulfotransferase 4 [Mus musculus] 74015 3160 0.196666667 0.143333333 -0.456378295 Down 0.138769792 Fcho1 FCH domain only 1 K20042|1|0.0|810|mmu:74015|F-BAR domain only protein - - - - 210503 2916 0.17 0.123333333 -0.462971976 Down 0.138769792 Zfp677 zinc finger protein 677 K09228|1|0.0|1345|mmu:210503|KRAB domain-containing zinc finger protein - - - "gi|148673777|gb|EDL05724.1|/0/RIKEN cDNA A830058L05, isoform CRA_a, partial [Mus musculus]" 100861870 3739 0.196666667 0.143333333 -0.456378295 Down 0.138769792 Gm21284 "predicted gene, 21284" - - - - "gi|68062440|ref|XP_673226.1|/8.44468e-15/hypothetical protein [Plasmodium berghei strain ANKA], partial [Plasmodium berghei ANKA]" 100504637 1116 0.133333333 0.183333333 0.459431619 Up 0.138769792 Gm20324 "predicted gene, 20324" - - - - - 12704 6898 0.183333333 0.133333333 -0.459431619 Down 0.138769792 Cit citron K16308|1|0.0|3666|mmu:12704|citron Rho-interacting kinase [EC:2.7.11.1] - - - gi|124487319|ref|NP_031734.3|/0/citron Rho-interacting kinase [Mus musculus] 21950 1230 0.37 0.31 -0.255257055 Down 0.138741585 Tnfsf9 "tumor necrosis factor (ligand) superfamily, member 9" K05472|1|3e-171|603|mmu:21950|tumor necrosis factor ligand superfamily member 9 GO:0031224//intrinsic component of membrane;GO:0044421 GO:0032813//tumor necrosis factor receptor superfamily binding GO:0045065//cytotoxic T cell differentiation;GO:0001819//positive regulation of cytokine production;GO:0042102//positive regulation of T cell proliferation;GO:0001773//myeloid dendritic cell activation gi|6678389|ref|NP_033430.1|/2.54342e-170/tumor necrosis factor ligand superfamily member 9 [Mus musculus] 208908 3920 0.286666667 0.343333333 0.260235772 Up 0.138741585 Ccdc62 coiled-coil domain containing 62 K20283|1|2e-10|71.6|mde:101892550|golgin subfamily A member 4;K20478|3|1e-09|68.9|dre:557772|golgin subfamily B member 1 GO:0043231//intracellular membrane-bounded organelle - - gi|198041652|ref|NP_001128239.1|/0/coiled-coil domain-containing protein 62 [Mus musculus] 22775 4191 0.326666667 0.39 0.255654875 Up 0.138741585 Zik1 zinc finger protein interacting with K protein 1 K09228|1|0.0|978|mmu:22775|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|31544067|ref|NP_033603.2|/0/zinc finger protein interacting with ribonucleoprotein K [Mus musculus] 17349 1176.11 45.42666667 44.43 -0.032005305 Down 0.138666366 Mlf1 myeloid leukemia factor 1 K15622|1|6e-153|542|mmu:17349|myeloid leukemia factor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding GO:0010467//gene expression;GO:0022402//cell cycle process;GO:0048869//cellular developmental process;GO:0010467//gene expression;GO:0022402//cell cycle process;GO:0048869//cellular developmental process gi|88196767|ref|NP_001034632.1|/4.4994e-161/myeloid leukemia factor 1 isoform a [Mus musculus] 75619 3205 10.84666667 11.18 0.043668438 Up 0.138609951 Fastkd2 FAST kinase domains 2 K18190|1|0.0|1324|mmu:75619|FAST kinase domain-containing protein 2 GO:0043231//intracellular membrane-bounded organelle GO:0016301//kinase activity GO:0006464//cellular protein modification process;GO:0015980//energy derivation by oxidation of organic compounds "gi|148667775|gb|EDL00192.1|/0/FAST kinase domains 2, isoform CRA_b [Mus musculus]" 217379 2511 12.55 12.22 -0.038443079 Down 0.138609951 Ubxn2a UBX domain protein 2A K14012|1|3e-49|199|xtr:448090|UBX domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005102//receptor binding GO:0009894;GO:0016567//protein ubiquitination;GO:0010467//gene expression "gi|148669402|gb|EDL01349.1|/1.40484e-132/UBX domain containing 4, isoform CRA_b, partial [Mus musculus]" 12153 4338.12 12.3 11.96666667 -0.039636972 Down 0.138609951 Bmp1 bone morphogenetic protein 1 K05502|1|0.0|1151|umr:103673342|bone morphogenetic protein 1 [EC:3.4.24.19] GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0005578//proteinaceous extracellular matrix GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0005102//receptor binding GO:0048869//cellular developmental process;GO:0051094//positive regulation of developmental process;GO:0001501//skeletal system development;GO:0019538//protein metabolic process gi|42734447|ref|NP_033885.2|/0/bone morphogenetic protein 1 precursor [Mus musculus] 28077 862 13.33 13.66 0.035280703 Up 0.138609951 Med10 mediator complex subunit 10 K15151|1|9e-72|272|cge:100759421|mediator of RNA polymerase II transcription subunit 10 GO:0043234//protein complex;GO:0031981//nuclear lumen "GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter gi|755545472|ref|XP_011242829.1|/3.98397e-80/PREDICTED: mediator of RNA polymerase II transcription subunit 10 isoform X2 [Mus musculus] 13885 1988 41.25666667 42.24 0.033982571 Up 0.138572342 Esd esterase D/formylglutathione hydrolase K01070|1|3e-168|594|mmu:13885|S-formylglutathione hydrolase [EC:3.1.2.12] GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle GO:0016790//thiolester hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0016790//thiolester hydrolase activity;GO:0052689//carboxylic ester hydrolase activity GO:0044282;GO:0044282 gi|12846304|dbj|BAB27115.1|/2.62771e-178/unnamed protein product [Mus musculus] 209239 2652 0.126666667 0.173333333 0.452512205 Up 0.138553537 Gan giant axonal neuropathy K10453|1|0.0|1170|mmu:209239|kelch-like protein 16 (gigaxonin) GO:0031461//cullin-RING ubiquitin ligase complex;GO:0005882//intermediate filament GO:0005488//binding GO:0032446//protein modification by small protein conjugation gi|124487231|ref|NP_001074620.1|/0/gigaxonin [Mus musculus] 270150 1086 0.173333333 0.126666667 -0.452512205 Down 0.138553537 Ccdc153 coiled-coil domain containing 153 - - - - gi|568959598|ref|XP_006510442.1|/2.22199e-87/PREDICTED: coiled-coil domain-containing protein 153 isoform X4 [Mus musculus] 241568 3440 0.173333333 0.126666667 -0.452512205 Down 0.138553537 Lrrc4c leucine rich repeat containing 4C K07523|1|0.0|1265|rno:311236|netrin-G1 ligand GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007409//axonogenesis;GO:0007409//axonogenesis;GO:0007409//axonogenesis;GO:0007409//axonogenesis gi|612034268|ref|XP_001362539.2|/0/PREDICTED: LOW QUALITY PROTEIN: leucine-rich repeat-containing protein 4C [Monodelphis domestica] 381353 4704 0.2 0.146666667 -0.447458977 Down 0.138553537 Gm996 predicted gene 996 - - - - gi|148762971|ref|NP_001005424.2|/0/uncharacterized protein C9orf172 homolog [Mus musculus] 78891 2637 51.58333333 50.61666667 -0.027292501 Down 0.138544135 Scyl1 SCY1-like 1 (S. cerevisiae) K08876|1|0.0|1480|mmu:78891|SCY1-like protein 1 GO:0015630//microtubule cytoskeleton;GO:0030120//vesicle coat GO:0032550;GO:0016301//kinase activity GO:0006464//cellular protein modification process;GO:0048193//Golgi vesicle transport gi|12963867|ref|NP_076401.1|/0/N-terminal kinase-like protein [Mus musculus] 71954 2409.68 46.76666667 47.73333333 0.029516484 Up 0.138544135 Suds3 suppressor of defective silencing 3 homolog (S. cerevisiae) K19201|1|9e-134|480|mmu:71954|Sin3 histone deacetylase corepressor complex component SDS3 GO:0070822//Sin3-type complex;GO:0070822//Sin3-type complex "GO:0042802//identical protein binding;GO:0019899//enzyme binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0042802//identical protein binding;GO:0019899//enzyme binding" "GO:0006476//protein deacetylation;GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization;GO:0006476//protein deacetylation;GO:0006915//apoptotic process;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter" gi|169881250|ref|NP_001116138.1|/7.3048e-136/sin3 histone deacetylase corepressor complex component SDS3 isoform b [Mus musculus] 72486 3456 1.066666667 0.973333333 -0.132103536 Down 0.13848772 Rnf219 ring finger protein 219 - - GO:0046914//transition metal ion binding - gi|88759344|ref|NP_080323.3|/0/RING finger protein 219 [Mus musculus] 70546 2498 1.026666667 1.12 0.125530882 Up 0.13848772 Zdhhc2 "zinc finger, DHHC domain containing 2" K20028|1|0.0|702|mmu:70546|palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225] GO:0031224//intrinsic component of membrane;GO:0010008//endosome membrane "GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0046914//transition metal ion binding" GO:0006497//protein lipidation gi|880867332|ref|XP_012966316.1|/0/PREDICTED: palmitoyltransferase ZDHHC2 [Mesocricetus auratus] 381104 1392 0.946666667 1.036666667 0.131023651 Up 0.13848772 Prickle4 prickle planar cell polarity protein 4 K04511|1|1e-59|233|gja:107107322|prickle - - - gi|594140660|ref|NP_001277266.1|/0/prickle-like protein 4 [Mus musculus] 19882 2565.78 0.943333333 1.03 0.126804785 Up 0.13848772 Mst1r macrophage stimulating 1 receptor (c-met-related tyrosine kinase) K05100|1|0.0|897|mmu:19882|macrophage-stimulating 1 receptor [EC:2.7.10.1] GO:0032432//actin filament bundle;GO:0031224//intrinsic component of membrane;GO:0032432//actin filament bundle;GO:0031224//intrinsic component of membrane;GO:0032432//actin filament bundle;GO:0031224//intrinsic component of membrane GO:0032550;GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0032550;GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0032550;GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity GO:0051707//response to other organism;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0043405//regulation of MAP kinase activity;GO:0006952//defense response;GO:0032502//developmental process;GO:0051707//response to other organism;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0043405//regulation of MAP kinase activity;GO:0006952//defense response;GO:0032502//developmental process;GO:0051707//response to other organism;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0043405//regulation of MAP kinase activity;GO:0006952//defense response;GO:0032502//developmental process gi|568962800|ref|XP_006511719.1|/0/PREDICTED: macrophage-stimulating protein receptor isoform X3 [Mus musculus] 381280 8449 1.076666667 0.983333333 -0.13081921 Down 0.13848772 Hjurp Holliday junction recognition protein - GO:0031981//nuclear lumen;GO:0000776//kinetochore GO:0005515//protein binding GO:0006461//protein complex assembly;GO:0043486//histone exchange;GO:0051098//regulation of binding gi|258613898|ref|NP_941054.2|/0/Holliday junction recognition protein [Mus musculus] 219114 2260 1.08 0.99 -0.125530882 Down 0.13848772 Ska3 spindle and kinetochore associated complex subunit 3 K11857|1|9e-22|108|ptg:102964137|ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12] GO:0005819//spindle;GO:0000777//condensed chromosome kinetochore GO:0005488//binding GO:0031109//microtubule polymerization or depolymerization;GO:0000087//mitotic M phase "gi|148704216|gb|EDL36163.1|/0/RIKEN cDNA F630043A04, isoform CRA_b [Mus musculus]" 20630 775 44.19 43.22666667 -0.031798341 Down 0.138478318 Snrpc U1 small nuclear ribonucleoprotein C K11095|1|2e-37|157|mcf:102133662|U1 small nuclear ribonucleoprotein C - - - "gi|148668239|gb|EDL00569.1|/1.45277e-48/mCG120852, partial [Mus musculus]" 108899 5017 6.04 5.82 -0.053529396 Down 0.138478318 2700081O15Rik RIKEN cDNA 2700081O15 gene - - - - gi|222144281|ref|NP_780590.3|/0/uncharacterized protein C11orf95 homolog [Mus musculus] 19654 3720 6.183333333 6.4 0.049687124 Up 0.138478318 Rbm6 RNA binding motif protein 6 K13094|1|1e-52|211|oaa:100082911|RNA-binding protein 5/10 - - - gi|60360110|dbj|BAD90274.1|/0/mKIAA4015 protein [Mus musculus] 20817 6436 5.663333333 5.88 0.054164708 Up 0.138478318 Srpk2 serine/arginine-rich protein specific kinase 2 K08831|1|0.0|1079|mmu:20817|serine/threonine-protein kinase SRPK2 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0046872//metal ion binding "GO:0019079//viral genome replication;GO:0008283//cell proliferation;GO:0006796//phosphate-containing compound metabolic process;GO:0051726//regulation of cell cycle;GO:0043065//positive regulation of apoptotic process;GO:0048869//cellular developmental process;GO:0006464//cellular protein modification process;GO:0030575//nuclear body organization;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0000398//mRNA splicing, via spliceosome;GO:0035556//intracellular signal transduction" gi|568933082|ref|XP_006535723.1|/0/PREDICTED: SRSF protein kinase 2 isoform X4 [Mus musculus] 22591 3634 6.156666667 5.94 -0.051686529 Down 0.138478318 Xpc "xeroderma pigmentosum, complementation group C" K10838|1|0.0|1535|mmu:22591|xeroderma pigmentosum group C-complementing protein GO:0031981//nuclear lumen;GO:0000109//nucleotide-excision repair complex GO:0000217//DNA secondary structure binding GO:0009411//response to UV;GO:0006289//nucleotide-excision repair;GO:0051276//chromosome organization;GO:0000077//DNA damage checkpoint gi|121247429|ref|NP_033557.2|/0/DNA repair protein complementing XP-C cells homolog [Mus musculus] 381038 1323 40.07 39.13 -0.0342474 Down 0.138365489 Parl "presenilin associated, rhomboid-like" K09650|1|0.0|764|mmu:381038|rhomboid-like protein [EC:3.4.21.105] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0004175//endopeptidase activity GO:0097193//intrinsic apoptotic signaling pathway;GO:0010823//negative regulation of mitochondrion organization;GO:0019538//protein metabolic process "gi|54261813|ref|NP_001005767.1|/0/presenilins-associated rhomboid-like protein, mitochondrial precursor [Mus musculus]" 73660 1472 0.203333333 0.15 -0.438884241 Down 0.138346685 Cabp4 calcium binding protein 4 K02183|1|2e-22|109|hro:HELRODRAFT_110019|calmodulin GO:0044444//cytoplasmic part GO:0043169//cation binding GO:0003407//neural retina development;GO:0050953//sensory perception of light stimulus;GO:0042462//eye photoreceptor cell development;GO:0007165//signal transduction gi|21746185|ref|NP_653115.1|/1.95669e-114/calcium-binding protein 4 [Mus musculus] 214253 2280 0.15 0.203333333 0.438884241 Up 0.138346685 Etnk2 ethanolamine kinase 2 K00894|1|0.0|778|mmu:214253|ethanolamine kinase [EC:2.7.1.82] - GO:0032550;GO:0016301//kinase activity GO:0046337//phosphatidylethanolamine metabolic process;GO:0043009//chordate embryonic development;GO:0040007//growth gi|158303302|ref|NP_780652.2|/0/ethanolamine kinase 2 [Mus musculus] 629147 1472 0.203333333 0.15 -0.438884241 Down 0.138346685 Ctxn3 cortexin 3 - GO:0031224//intrinsic component of membrane - - gi|197927416|ref|NP_001128168.1|/6.23971e-28/cortexin-3 [Rattus norvegicus] 66496 797 49.72333333 50.65 0.026639255 Up 0.138309075 Ppdpf pancreatic progenitor cell differentiation and proliferation factor - - - - - 328580 6957 4.496666667 4.323333333 -0.056711869 Down 0.138271466 Tubgcp6 "tubulin, gamma complex associated protein 6" K16573|1|0.0|3457|mmu:328580|gamma-tubulin complex component 6 GO:0000931//gamma-tubulin large complex GO:0015631//tubulin binding GO:0000226//microtubule cytoskeleton organization gi|254039634|ref|NP_001156791.1|/0/gamma-tubulin complex component 6 [Mus musculus] 74315 3598 4.286666667 4.116666667 -0.058379601 Down 0.138271466 Rnf145 ring finger protein 145 K15703|1|4e-64|249|sko:100368162|E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27];K09103|4|8e-58|228|clv:102089892|early B-cell factor GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - gi|74226603|dbj|BAE23952.1|/1.49394e-172/unnamed protein product [Mus musculus] 107522 1220.83 4.326666667 4.153333333 -0.058986315 Down 0.138271466 Ece2 endothelin converting enzyme 2 K01415|1|0.0|1704|mmu:107522|endothelin-converting enzyme [EC:3.4.24.71] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012506//vesicle membrane GO:0043169//cation binding;GO:0016741;GO:0004175//endopeptidase activity GO:0007417//central nervous system development;GO:0035051//cardiocyte differentiation;GO:0016485//protein processing;GO:0007154//cell communication gi|120953156|ref|NP_079738.2|/2.19235e-147/endothelin-converting enzyme 2 isoform c [Mus musculus] 103806 5573 4.256666667 4.083333333 -0.059976776 Down 0.138271466 Maml1 mastermind like 1 (Drosophila) K06061|1|0.0|1725|mmu:103806|mastermind GO:0005654//nucleoplasm;GO:0043234//protein complex GO:0003823//antigen binding;GO:0003712//transcription cofactor activity;GO:0019900//kinase binding GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0060922;GO:0010830//regulation of myotube differentiation;GO:0006464//cellular protein modification process gi|157838023|ref|NP_780543.2|/0/mastermind-like protein 1 [Mus musculus] 101543 1958 4.303333333 4.473333333 0.055895671 Up 0.138271466 Wtip WT1-interacting protein K16682|1|2e-156|555|mmu:101543|LIM domain-containing protein GO:0035770//ribonucleoprotein granule GO:0005488//binding;GO:0003712//transcription cofactor activity GO:0006996//organelle organization;GO:0009968//negative regulation of signal transduction;GO:0000902//cell morphogenesis;GO:0006950//response to stress;GO:0035195//gene silencing by miRNA gi|755518982|ref|XP_011248711.1|/1.10052e-158/PREDICTED: Wilms tumor protein 1-interacting protein isoform X1 [Mus musculus] 382985 4532 3.843333333 4.013333333 0.062442879 Up 0.138271466 Rrm2b ribonucleotide reductase M2 B (TP53 inducible) K10808|1|0.0|709|mmu:382985|ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0046872//metal ion binding;GO:0016728 GO:0006915//apoptotic process;GO:0033554//cellular response to stress;GO:0009165//nucleotide biosynthetic process;GO:0003008;GO:0006261//DNA-dependent DNA replication;GO:0009132//nucleoside diphosphate metabolic process;GO:0009141//nucleoside triphosphate metabolic process gi|41054952|ref|NP_955770.1|/0/ribonucleoside-diphosphate reductase subunit M2 B [Mus musculus] 212943 5450 3.856666667 4.023333333 0.061036812 Up 0.138271466 Fam46a "family with sequence similarity 46, member A" "K05742|1|0.0|659|apla:101803574|solute carrier family 9 (sodium/hydrogen exchanger), member 1" - - - gi|237874155|ref|NP_001153850.1|/0/protein FAM46A isoform 1 [Mus musculus] 231279 5018 4.35 4.523333333 0.056370914 Up 0.138271466 Guf1 "GUF1 homolog, GTPase" K03596|1|0.0|753|nve:NEMVE_v1g106275|GTP-binding protein LepA;K04771|2|7e-155|551|lve:103072277|serine protease Do [EC:3.4.21.107];K02355|3|2e-27|128|cbr:CBG15144|elongation factor G;K14536|4|2e-25|121|myd:102774231|ribosome assembly protein 1 [EC:3.6.5.-] - - - - 16593 2245.18 39.10333333 40.02333333 0.033549733 Up 0.138252661 Klc1 kinesin light chain 1 K10407|1|0.0|910|ptg:102970489|kinesin light chain GO:0005875//microtubule associated complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0031982//vesicle;GO:0044444//cytoplasmic part;GO:0005875//microtubule associated complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0031982//vesicle;GO:0044444//cytoplasmic part;GO:0005875//microtubule associated complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0031982//vesicle;GO:0044444//cytoplasmic part;GO:0005875//microtubule associated complex;GO:0044444//cytoplasmic part GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding;GO:0005488//binding;GO:0003774//motor activity GO:0032988;GO:0015031//protein transport;GO:0010970//transport along microtubule;GO:0032988;GO:0015031//protein transport;GO:0010970//transport along microtubule;GO:0032988;GO:0015031//protein transport;GO:0010970//transport along microtubule;GO:0002478;GO:0006928//movement of cell or subcellular component;GO:0007599//hemostasis;GO:0032988 gi|575403064|ref|NP_001020534.2|/0/kinesin light chain 1 isoform 1F [Mus musculus] 171286 3050 0.746666667 0.666666667 -0.163498732 Down 0.138168039 Slc12a8 "solute carrier family 12 (potassium/chloride transporters), member 8" "K14428|1|0.0|1267|mmu:171286|solute carrier family 12 (potassium/chloride transporters), member 8" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0030001//metal ion transport;GO:0044763;GO:0030001//metal ion transport;GO:0044763 gi|144226223|ref|NP_599012.2|/0/solute carrier family 12 member 8 isoform 1 [Mus musculus] 55944 1910 44.82 45.71666667 0.028577568 Up 0.138139832 Eif3d "eukaryotic translation initiation factor 3, subunit D" K03251|1|0.0|1091|ngi:103748629|translation initiation factor 3 subunit D GO:0043234//protein complex;GO:0044424 "GO:0008135//translation factor activity, RNA binding" GO:0006413//translational initiation "gi|148697712|gb|EDL29659.1|/0/eukaryotic translation initiation factor 3, subunit 7 (zeta), isoform CRA_c, partial [Mus musculus]" 50799 3130.76 44.46666667 45.37 0.029014399 Up 0.138139832 Slc25a13 "solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13" "K15105|1|0.0|1332|mmu:50799|solute carrier family 25 (mitochondrial aspartate/glutamate transporter), member 12/13" GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0019866//organelle inner membrane GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0046872//metal ion binding;GO:0005310//dicarboxylic acid transmembrane transporter activity;GO:0046872//metal ion binding GO:0006865//amino acid transport;GO:0044763;GO:0009152//purine ribonucleotide biosynthetic process;GO:0010038//response to metal ion;GO:0006006//glucose metabolic process;GO:0015740//C4-dicarboxylate transport;GO:0022904//respiratory electron transport chain;GO:0006865//amino acid transport;GO:0044763;GO:0009152//purine ribonucleotide biosynthetic process;GO:0010038//response to metal ion;GO:0006006//glucose metabolic process;GO:0015740//C4-dicarboxylate transport;GO:0022904//respiratory electron transport chain gi|294832028|ref|NP_001171043.1|/0/calcium-binding mitochondrial carrier protein Aralar2 isoform 2 [Mus musculus] 13123 2166 0.2 0.15 -0.415037499 Down 0.138121027 Cyp7b1 "cytochrome P450, family 7, subfamily b, polypeptide 1" K07430|1|0.0|916|mmu:13123|oxysterol 7-alpha-hydroxylase [EC:1.14.13.100] GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0046914//transition metal ion binding;GO:0008395//steroid hydroxylase activity;GO:0046906//tetrapyrrole binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen" GO:0048511//rhythmic process;GO:0016125//sterol metabolic process;GO:0007611//learning or memory;GO:0006694//steroid biosynthetic process;GO:0046683//response to organophosphorus;GO:0008284//positive regulation of cell proliferation;GO:0002009//morphogenesis of an epithelium;GO:0030520//intracellular estrogen receptor signaling pathway gi|160707927|ref|NP_031851.3|/0/25-hydroxycholesterol 7-alpha-hydroxylase [Mus musculus] 94284 3302 0.183333333 0.136666667 -0.423807709 Down 0.138121027 Ugt1a6a "UDP glucuronosyltransferase 1 family, polypeptide A6A" K00699|1|0.0|1087|mmu:94284|glucuronosyltransferase [EC:2.4.1.17] GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0005501//retinoid binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0008194//UDP-glycosyltransferase activity GO:0006063;GO:0051384//response to glucocorticoid;GO:0002237//response to molecule of bacterial origin;GO:0006725//cellular aromatic compound metabolic process gi|33186906|ref|NP_659545.2|/0/UDP-glucuronosyltransferase 1-6 precursor [Mus musculus] 94244 1327 0.21 0.156666667 -0.422691072 Down 0.138121027 Fkbp6 FK506 binding protein 6 K09572|1|1e-163|578|mmu:94244|FK506-binding protein 6 [EC:5.2.1.8] - - - - 434353 2489 0.193333333 0.143333333 -0.43171624 Down 0.138121027 A330074K22Rik RIKEN cDNA A330074K22 gene - - - - "gi|148679687|gb|EDL11634.1|/7.01382e-76/mCG144610, partial [Mus musculus]" 110379 1301 47.26 48.15 0.026916169 Up 0.138064613 Sec13 "SEC13 homolog, nuclear pore and COPII coat complex component" K14004|1|0.0|686|mmu:110379|protein transport protein SEC13 "GO:0005643//nuclear pore;GO:0030134//ER to Golgi transport vesicle;GO:0000775//chromosome, centromeric region;GO:0031090//organelle membrane" - GO:0050658//RNA transport;GO:0045184//establishment of protein localization;GO:0016482//cytosolic transport gi|29150272|ref|NP_077168.2|/0/protein SEC13 homolog [Mus musculus] 353172 2390 44.39666667 43.52 -0.028772805 Down 0.138027004 Gars glycyl-tRNA synthetase K01880|1|0.0|1319|mmu:353172|glycyl-tRNA synthetase [EC:6.1.1.14] "GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0032550;GO:0005515//protein binding;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation;GO:0015960 "gi|148666303|gb|EDK98719.1|/0/glycyl-tRNA synthetase, isoform CRA_b, partial [Mus musculus]" 100502940 1263 1.423333333 1.32 -0.10873564 Down 0.138017601 Gm684 predicted gene 684 - - - - "gi|148693830|gb|EDL25777.1|/2.95112e-121/mCG127934, partial [Mus musculus]" 100637 1907 1.413333333 1.313333333 -0.105868635 Down 0.138017601 N4bp2l1 NEDD4 binding protein 2-like 1 K15720|1|2e-47|193|cmk:103175864|NEDD4-binding protein 2 [EC:3.-.-.-] - - - "gi|148673934|gb|EDL05881.1|/1.45052e-123/RIKEN cDNA B230342M21, partial [Mus musculus]" 102466886 137 1.256666667 1.36 0.114004629 Up 0.138017601 Mir8111 microRNA 8111 - - - - - 77987 7477 1.173333333 1.27 0.114215569 Up 0.138017601 Ascc3 activating signal cointegrator 1 complex subunit 3 K18663|1|0.0|4350|mmu:77987|activating signal cointegrator complex subunit 3 [EC:3.6.4.12] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004003//ATP-dependent DNA helicase activity "GO:0006351//transcription, DNA-templated;GO:0009154//purine ribonucleotide catabolic process;GO:0032392//DNA geometric change;GO:0006281//DNA repair" gi|225703058|ref|NP_932124.2|/0/activating signal cointegrator 1 complex subunit 3 [Mus musculus] 70430 1870.1 10.45 10.77 0.043515308 Up 0.138008199 Tbce tubulin-specific chaperone E K18273|1|7e-17|91.7|pps:100980308|alpha-tectorin;K16768|2|8e-08|61.6|dre:100004437|centrosomal protein CEP350;K17914|3|1e-06|57.8|cmk:103184897|kinesin family member 13;K10423|4|2e-06|57.0|hmg:100215011|CAP-Gly domain-containing linker protein 3/4 GO:0043232 GO:0005515//protein binding GO:0006457//protein folding;GO:0040007//growth;GO:0007010//cytoskeleton organization;GO:0007626//locomotory behavior;GO:0043623//cellular protein complex assembly;GO:0043500;GO:0007409//axonogenesis gi|31543843|ref|NP_848027.1|/0/tubulin-specific chaperone E [Mus musculus] 105352 3058 11.18666667 10.86666667 -0.041870751 Down 0.138008199 Dusp22 dual specificity phosphatase 22 K14165|1|4e-104|380|mmu:105352|atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] - - - - 68079 1283 12.25333333 11.93666667 -0.037774248 Down 0.138008199 Pdcd2l programmed cell death 2-like K14801|1|0.0|762|mmu:68079|pre-rRNA-processing protein TSR4 GO:0044424 - GO:0044763 gi|58037105|ref|NP_080825.1|/0/programmed cell death protein 2-like [Mus musculus] 13667 1773.47 41.70333333 42.57333333 0.02978735 Up 0.137989394 Eif2b4 "eukaryotic translation initiation factor 2B, subunit 4 delta" K03680|1|0.0|842|mmu:13667|translation initiation factor eIF-2B subunit delta - - - "gi|529428|gb|AAA68046.1|/0/guanine nucleotide exchange factor, eIF-2B, delta subunit [Mus musculus]" 26397 2166 48.49 47.62666667 -0.025917674 Down 0.137876565 Map2k3 mitogen-activated protein kinase kinase 3 K04432|1|0.0|745|rno:103689956|mitogen-activated protein kinase kinase 3 [EC:2.7.12.2] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0032550;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0019900//kinase binding "GO:0001934//positive regulation of protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0006941//striated muscle contraction;GO:0007166//cell surface receptor signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0001817//regulation of cytokine production;GO:0000165//MAPK cascade" gi|672068112|ref|XP_008766106.1|/0/PREDICTED: dual specificity mitogen-activated protein kinase kinase 3 [Rattus norvegicus] 59003 2128 48.63 49.48333333 0.025096096 Up 0.137810749 Maea macrophage erythroblast attacher K18624|1|0.0|735|ngi:103741119|macrophage erythroblast attacher GO:0015630//microtubule cytoskeleton;GO:0016021//integral component of membrane;GO:0034399//nuclear periphery;GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding GO:0000278//mitotic cell cycle;GO:0006996//organelle organization;GO:0022610;GO:0043353//enucleate erythrocyte differentiation;GO:0048469//cell maturation;GO:0043066//negative regulation of apoptotic process gi|8099667|gb|AAF72195.1|AF263247_1/0/erythroblast macrophage protein EMP [Mus musculus] 20807 4093 44.17333333 45.02666667 0.027603976 Up 0.137810749 Srf serum response factor K04378|1|0.0|659|mmu:20807|serum response factor - - - - 99100 5768 0.51 0.443333333 -0.202105407 Down 0.137782542 Cep152 centrosomal protein 152 K16728|1|0.0|3060|mmu:99100|centrosomal protein CEP152 - - - gi|50510705|dbj|BAD32338.1|/0/mKIAA0912 protein [Mus musculus] 12705 773 0.466666667 0.536666667 0.201633861 Up 0.137782542 Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 K02987|1|5e-07|57.8|fpg:101913201|small subunit ribosomal protein S4e GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0019904//protein domain specific binding;GO:0000975//regulatory region DNA binding;GO:0046332//SMAD binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0019904//protein domain specific binding;GO:0000975//regulatory region DNA binding;GO:0046332//SMAD binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0019904//protein domain specific binding;GO:0000975//regulatory region DNA binding;GO:0046332//SMAD binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0019904//protein domain specific binding;GO:0000975//regulatory region DNA binding;GO:0046332//SMAD binding "GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043434//response to peptide hormone;GO:0048754//branching morphogenesis of an epithelial tube;GO:0050931//pigment cell differentiation;GO:0006351//transcription, DNA-templated;GO:0009880//embryonic pattern specification;GO:0001892//embryonic placenta development;GO:0001649//osteoblast differentiation;GO:0051169//nuclear transport;GO:0002237//response to molecule of bacterial origin;GO:0046683//response to organophosphorus;GO:0048545//response to steroid hormone;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0034097//response to cytokine;GO:0006582//melanin metabolic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043434//response to peptide hormone;GO:0048754//branching morphogenesis of an epithelial tube;GO:0050931//pigment cell differentiation;GO:0006351//transcription, DNA-templated;GO:0009880//embryonic pattern specification;GO:0001892//embryonic placenta development;GO:0001649//osteoblast differentiation;GO:0051169//nuclear transport;GO:0002237//response to molecule of bacterial origin;GO:0046683//response to organophosphorus;GO:0048545//response to steroid hormone;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0034097//response to cytokine;GO:0006582//melanin metabolic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043434//response to peptide hormone;GO:0048754//branching morphogenesis of an epithelial tube;GO:0050931//pigment cell differentiation;GO:0006351//transcription, DNA-templated;GO:0009880//embryonic pattern specification;GO:0001892//embryonic placenta development;GO:0001649//osteoblast differentiation;GO:0051169//nuclear transport;GO:0002237//response to molecule of bacterial origin;GO:0046683//response to organophosphorus;GO:0048545//response to steroid hormone;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0034097//response to cytokine;GO:0006582//melanin metabolic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043434//response to peptide hormone;GO:0048754//branching morphogenesis of an epithelial tube;GO:0050931//pigment cell differentiation;GO:0006351//transcription, DNA-templated;GO:0009880//embryonic pattern specification;GO:0001892//embryonic placenta development;GO:0001649//osteoblast differentiation;GO:0051169//nuclear transport;GO:0002237//response to molecule of bacterial origin;GO:0046683//response to organophosphorus;GO:0048545//response to steroid hormone;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0034097//response to cytokine;GO:0006582//melanin metabolic process" "gi|148682178|gb|EDL14125.1|/5.2854e-83/Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1, isoform CRA_a, partial [Mus musculus]" 232854 2700 0.47 0.54 0.20029865 Up 0.137782542 Zfp418 zinc finger protein 418 K09228|1|0.0|1371|mmu:232854|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|124339857|ref|NP_666291.2|/0/zinc finger protein 418 [Mus musculus] 239827 2184 0.563333333 0.49 -0.201207091 Down 0.137782542 Pigz "phosphatidylinositol glycan anchor biosynthesis, class Z" "K08098|1|0.0|927|mmu:239827|phosphatidylinositol glycan, class Z [EC:2.4.1.-]" GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane "GO:0016758//transferase activity, transferring hexosyl groups" GO:0006497//protein lipidation "gi|148665343|gb|EDK97759.1|/0/phosphatidylinositol glycan anchor biosynthesis, class Z [Mus musculus]" 75697 1348 0.48 0.55 0.196397213 Up 0.137782542 C2cd4b C2 calcium-dependent domain containing 4B K15290|1|5e-08|61.6|crg:105338029|synaptotagmin-1 GO:0005924//cell-substrate adherens junction - - gi|124486785|ref|NP_001074783.1|/9.75448e-142/C2 calcium-dependent domain-containing protein 4B [Mus musculus] 68059 3062 47.21 48.04666667 0.025343862 Up 0.137726127 Tm9sf2 transmembrane 9 superfamily member 2 K17086|1|0.0|1298|mmu:68059|transmembrane 9 superfamily member 2/4 GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|188528894|ref|NP_542123.3|/0/transmembrane 9 superfamily member 2 precursor [Mus musculus] 384864 1122 11.05666667 10.74333333 -0.041474824 Down 0.137575689 Gm1943 WD repeat domain 70 pseudogene - - - - gi|38174374|gb|AAH61236.1|/3.54396e-43/WD repeat domain 70 [Mus musculus] 381085 3505 10.63666667 10.94333333 0.041006141 Up 0.137575689 Tbc1d22b "TBC1 domain family, member 22B" K20360|1|0.0|1031|mmu:381085|TBC1 domain family member 2 GO:0044464 - - gi|38348532|ref|NP_941049.1|/0/TBC1 domain family member 22B [Mus musculus] 66622 3247 12.24 12.55 0.036083806 Up 0.137575689 Ubr7 ubiquitin protein ligase E3 component n-recognin 7 (putative) K11979|1|0.0|806|mmu:66622|E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27] - - - gi|148686905|gb|EDL18852.1|/0/RIKEN cDNA 5730410I19 [Mus musculus] 76332 2839 9.846666667 10.15666667 0.044719674 Up 0.137575689 Cog2 component of oligomeric golgi complex 2 K20289|1|0.0|1240|mmu:76332|conserved oligomeric Golgi complex subunit 2 GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0022892//substrate-specific transporter activity GO:0048193//Golgi vesicle transport;GO:0006996//organelle organization gi|256985208|ref|NP_084022.2|/0/conserved oligomeric Golgi complex subunit 2 [Mus musculus] 93692 1335 34.39666667 33.58 -0.034666532 Down 0.137509873 Glrx glutaredoxin K03676|1|1e-54|216|mmu:93692|glutaredoxin 3 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0015037//peptide disulfide oxidoreductase activity;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0005515//protein binding" GO:0051234//establishment of localization;GO:0019725//cellular homeostasis;GO:0055086//nucleobase-containing small molecule metabolic process;GO:0006091//generation of precursor metabolites and energy gi|31981458|ref|NP_444338.2|/9.84196e-54/glutaredoxin-1 [Mus musculus] 54630 2410 35.28333333 34.46 -0.034064162 Down 0.137509873 Prickle3 prickle planar cell polarity protein 3 K04511|1|1e-168|596|lcm:102352970|prickle - GO:0046914//transition metal ion binding - "gi|23270998|gb|AAH23671.1|/0/Prickle3 protein, partial [Mus musculus]" 233208 4195 38.17666667 39 0.030782982 Up 0.137509873 Scaf1 SR-related CTD-associated factor 1 K17586|1|1e-34|151|chx:102185540|PHD and RING finger domain-containing protein 1 - GO:0005515//protein binding "GO:0006351//transcription, DNA-templated;GO:0006396//RNA processing" "gi|672036577|ref|XP_008757631.1|/0/PREDICTED: splicing factor, arginine/serine-rich 19 isoform X1 [Rattus norvegicus]" 68188 4121 45.89666667 46.70666667 0.025239108 Up 0.137444056 Sympk symplekin K06100|1|0.0|2384|mmu:68188|symplekin GO:0043296//apical junction complex;GO:0031981//nuclear lumen;GO:0043232;GO:0016020//membrane GO:0005488//binding GO:0006470//protein dephosphorylation;GO:0022610;GO:0031124//mRNA 3'-end processing gi|148691154|gb|EDL23101.1|/0/mCG4849 [Mus musculus] 19018 780 46.21666667 47.02666667 0.025065864 Up 0.137444056 Scand1 SCAN domain-containing 1 K09229|1|5e-13|77.0|ocu:100347828|KRAB and SCAN domains-containing zinc finger protein;K09230|2|2e-11|71.6|ecb:100067081|SCAN domain-containing zinc finger protein - - - gi|60360240|dbj|BAD90364.1|/1.53241e-37/mKIAA4092 protein [Mus musculus] 114715 6201.78 3.056666667 3.2 0.066112672 Up 0.137284215 Spred1 "sprouty protein with EVH-1 domain 1, related sequence" "K04703|1|0.0|840|mmu:114715|sprouty-related, EVH1 domain-containing protein" GO:0031981//nuclear lumen;GO:0044459;GO:0031981//nuclear lumen;GO:0044459 GO:0005126//cytokine receptor binding;GO:0004860//protein kinase inhibitor activity;GO:0019900//kinase binding;GO:0005126//cytokine receptor binding;GO:0004860//protein kinase inhibitor activity;GO:0019900//kinase binding "GO:0043407//negative regulation of MAP kinase activity;GO:0010921//regulation of phosphatase activity;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0032502//developmental process;GO:0043407//negative regulation of MAP kinase activity;GO:0010921//regulation of phosphatase activity;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0032502//developmental process" "gi|15743554|ref|NP_277059.1|/0/sprouty-related, EVH1 domain-containing protein 1 isoform 1 [Mus musculus]" 268783 4518 3.02 2.883333333 -0.066810918 Down 0.137284215 Mtmr12 myotubularin related protein 12 K18085|1|0.0|1487|mmu:268783|myotubularin-related protein 10/11/12 GO:0044424 GO:0042578//phosphoric ester hydrolase activity GO:0006796//phosphate-containing compound metabolic process gi|28972810|dbj|BAC65821.1|/0/mKIAA1682 protein [Mus musculus] 76559 10173 2.926666667 2.786666667 -0.070717997 Down 0.137284215 Atg2b autophagy related 2B K17906|1|0.0|3990|mmu:76559|autophagy-related protein 2 - - - gi|118197274|ref|NP_083930.5|/0/autophagy-related protein 2 homolog B [Mus musculus] 226255 6596 3.026666667 3.166666667 0.065235216 Up 0.137284215 Atrnl1 attractin like 1 "K10895|1|2e-57|228|aqu:100636243|fanconi anemia group I protein;K03177|3|6e-25|120|mgp:100548652|tRNA pseudouridine55 synthase [EC:5.4.99.25];K06243|4|2e-14|85.9|chx:102179246|laminin, beta 2" GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0007166//cell surface receptor signaling pathway gi|50510519|dbj|BAD32245.1|/0/mKIAA0534 protein [Mus musculus] 234577 2328 2.82 2.683333333 -0.07166888 Down 0.137284215 Cpne2 copine II K11348|1|5e-12|75.9|apla:101800649|bromodomain and PHD finger-containing protein 1;K19910|2|1e-09|67.8|tca:658788|synaptotagmin-10;K19906|3|2e-09|67.0|sko:100376714|synaptotagmin-6;K15290|4|7e-09|65.5|cel:CELE_F31E8.2|synaptotagmin-1 - - - "gi|148679188|gb|EDL11135.1|/0/copine II, isoform CRA_a, partial [Mus musculus]" 66131 1854.93 2.823333333 2.686666667 -0.071582131 Down 0.137284215 Tipin timeless interacting protein K10904|1|1e-117|426|mmu:66131|TIMELESS-interacting protein - - - - 71952 2346 2.74 2.88 0.071892918 Up 0.137284215 2410016O06Rik RIKEN cDNA 2410016O06 gene K16914|1|0.0|1146|mmu:71952|bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [EC:1.14.11.- 1.14.11.27] - - - - 66870 6661.18 38.82666667 38.02666667 -0.030036374 Down 0.137284215 Serbp1 serpine1 mRNA binding protein 1 K13199|1|2e-149|534|mmu:66870|plasminogen activator inhibitor 1 RNA-binding protein GO:0016020//membrane;GO:0044424;GO:0044424;GO:0016020//membrane;GO:0044424;GO:0044424 GO:0003729//mRNA binding;GO:0003729//mRNA binding;GO:0003729//mRNA binding GO:0006915//apoptotic process;GO:0050789;GO:0006915//apoptotic process;GO:0050789 gi|397470815|ref|XP_003807008.1|/1.08704e-148/PREDICTED: plasminogen activator inhibitor 1 RNA-binding protein isoform X1 [Pan paniscus] 75686 1606 2.796666667 2.656666667 -0.074091086 Down 0.137284215 Nudt16 nudix (nucleoside diphosphate linked moiety X)-type motif 16 K16855|1|4e-87|324|mmu:75686|U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64] - - - - 241289 5485 0.75 0.83 0.146220741 Up 0.137274813 Ppp1r26 "protein phosphatase 1, regulatory subunit 26" K17565|1|0.0|2088|mmu:241289|protein phosphatase 1 regulatory subunit 26 GO:0031981//nuclear lumen GO:0019899//enzyme binding GO:0010921//regulation of phosphatase activity;GO:0044092//negative regulation of molecular function gi|50510571|dbj|BAD32271.1|/0/mKIAA0649 protein [Mus musculus] 320398 4050 0.83 0.746666667 -0.15264701 Down 0.137274813 Lrig3 leucine-rich repeats and immunoglobulin-like domains 3 K19511|1|2e-53|214|clv:102088601|peroxidase [EC:1.11.1.7] GO:0012506//vesicle membrane;GO:0031224//intrinsic component of membrane - GO:0032502//developmental process gi|283135157|ref|NP_796126.4|/0/leucine-rich repeats and immunoglobulin-like domains protein 3 precursor [Mus musculus] 66074 10809 0.706666667 0.783333333 0.148596492 Up 0.137274813 Tmem167 transmembrane protein 167 K11290|1|5e-10|71.6|rno:317165|template-activating factor I GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|26344343|dbj|BAC35822.1|/1.73274e-34/unnamed protein product [Mus musculus] 210356 6500.14 0.68 0.756666667 0.154123145 Up 0.137274813 Nckap5 NCK-associated protein 5 K18401|1|8e-16|89.0|acs:100558460|KAT8 regulatory NSL complex subunit 2 - - - gi|126362961|ref|NP_001075225.1|/0/nck-associated protein 5 isoform 1 [Mus musculus] 100504121 529 0.793333333 0.713333333 -0.153350777 Down 0.137274813 Med9os "mediator complex subunit 9, opposite strand" - - - - - 72504 5149 0.756666667 0.68 -0.154123145 Down 0.137274813 Taf4b TATA-box binding protein associated factor 4b K03129|1|0.0|1500|mmu:72504|transcription initiation factor TFIID subunit 4 GO:0043234//protein complex GO:0008134//transcription factor binding GO:0006366//transcription from RNA polymerase II promoter gi|226958537|ref|NP_001093919.1|/0/transcription initiation factor TFIID subunit 4B [Mus musculus] 100039495 886 0.74 0.82 0.148098639 Up 0.137274813 Gm15706 predicted gene 15706 - - - - - 68925 4765.45 6.413333333 6.626666667 0.047208958 Up 0.137208996 Rpap1 RNA polymerase II associated protein 1 - GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0034062//RNA polymerase activity;GO:0034062//RNA polymerase activity GO:0010467//gene expression;GO:0010467//gene expression gi|28972742|dbj|BAC65787.1|/0/mKIAA1403 protein [Mus musculus] 244202 4483 6.09 6.296666667 0.048146068 Up 0.137208996 Nlrp10 "NLR family, pyrin domain containing 10" "K12800|1|4e-81|306|pps:100984425|NACHT, LRR and PYD domains-containing protein 3" GO:0019898//extrinsic component of membrane;GO:0044424 GO:0032550;GO:0016462//pyrophosphatase activity GO:0032675//regulation of interleukin-6 production;GO:0042742//defense response to bacterium;GO:0050715//positive regulation of cytokine secretion;GO:0050900//leukocyte migration;GO:0002824 gi|74197257|dbj|BAE43265.1|/0/unnamed protein product [Mus musculus] 330096 3754 0.58 0.51 -0.185555653 Down 0.137124375 Shisa3 shisa family member 3 - - - - - 270685 3731 0.53 0.463333333 -0.193941883 Down 0.137124375 Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like "K13402|1|0.0|1768|mmu:270685|monofunctional C1-tetrahydrofolate synthase, mitochondrial [EC:6.3.4.3]" - - - "gi|148671648|gb|EDL03595.1|/0/methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like, isoform CRA_a, partial [Mus musculus]" 55994 5380 0.463333333 0.53 0.193941883 Up 0.137124375 Smad9 SMAD family member 9 K16791|1|0.0|873|mmu:55994|mothers against decapentaplegic homolog 9 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0043169//cation binding "GO:0001501//skeletal system development;GO:0006351//transcription, DNA-templated;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0003006//developmental process involved in reproduction;GO:0007420//brain development;GO:0014070//response to organic cyclic compound;GO:0030154//cell differentiation;GO:0006464//cellular protein modification process;GO:0035295//tube development;GO:0006950//response to stress" gi|84490384|ref|NP_062356.3|/0/mothers against decapentaplegic homolog 9 [Mus musculus] 224829 4560 0.543333333 0.476666667 -0.188856817 Down 0.137124375 Trerf1 transcriptional regulating factor 1 K11829|1|1e-09|68.9|xla:398247|REST corepressor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148691603|gb|EDL23550.1|/0/transcriptional regulating factor 1, isoform CRA_b, partial [Mus musculus]" 107351 5425 10.39 10.69333333 0.041515987 Up 0.137077363 Kank1 KN motif and ankyrin repeat domains 1 K15503|1|9e-21|106|aqu:100635111|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B - - - gi|75677563|ref|NP_852069.4|/0/KN motif and ankyrin repeat domain-containing protein 1 [Mus musculus] 14852 6854.57 11.59666667 11.89333333 0.036442936 Up 0.137077363 Gspt1 G1 to S phase transition 1 K03267|1|0.0|1044|mmu:14852|peptide chain release factor subunit 3 - GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008079//translation termination factor activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008079//translation termination factor activity GO:0008213;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0010467//gene expression;GO:0008213;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0010467//gene expression "gi|148664930|gb|EDK97346.1|/0/G1 to S phase transition 1, isoform CRA_b, partial [Mus musculus]" 67091 782 9.98 9.676666667 -0.044529649 Down 0.137077363 Trappc6a trafficking protein particle complex 6A K20304|1|1e-87|324|mmu:67091|trafficking protein particle complex subunit 6 GO:0043231//intracellular membrane-bounded organelle - GO:0006810//transport "gi|148691203|gb|EDL23150.1|/4.90731e-102/trafficking protein particle complex 6A, isoform CRA_a, partial [Mus musculus]" 13665 3152 11.41333333 11.71 0.037020875 Up 0.137077363 Eif2s1 "eukaryotic translation initiation factor 2, subunit 1 alpha" K03237|1|9e-148|527|myd:102767480|translation initiation factor 2 subunit 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0035770//ribonucleoprotein granule "GO:0043021//ribonucleoprotein complex binding;GO:0008135//translation factor activity, RNA binding" GO:0006468//protein phosphorylation;GO:0006446//regulation of translational initiation gi|861417632|ref|XP_004837426.2|/2.0134e-147/PREDICTED: eukaryotic translation initiation factor 2 subunit 1 isoform X1 [Heterocephalus glaber] 74254 1847 9.486666667 9.783333333 0.044424841 Up 0.137077363 Gpn1 GPN-loop GTPase 1 K06883|1|0.0|674|mmu:74254|uncharacterized protein GO:0043227//membrane-bounded organelle;GO:0044424 GO:0016462//pyrophosphatase activity;GO:0032550 - gi|19526970|ref|NP_598517.1|/0/GPN-loop GTPase 1 [Mus musculus] 225010 4446.8 40.58333333 41.34666667 0.026883659 Up 0.13690812 Lclat1 lysocardiolipin acyltransferase 1 K13513|1|0.0|786|mmu:225010|lysocardiolipin and lysophospholipid acyltransferase [EC:2.3.1.- 2.3.1.51] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0016411//acylglycerol O-acyltransferase activity;GO:0016411//acylglycerol O-acyltransferase activity;GO:0016411//acylglycerol O-acyltransferase activity GO:0046341//CDP-diacylglycerol metabolic process;GO:0006641//triglyceride metabolic process;GO:0032048//cardiolipin metabolic process;GO:0046473//phosphatidic acid metabolic process;GO:0032502//developmental process;GO:0046341//CDP-diacylglycerol metabolic process;GO:0006641//triglyceride metabolic process;GO:0032048//cardiolipin metabolic process;GO:0046473//phosphatidic acid metabolic process;GO:0032502//developmental process;GO:0046341//CDP-diacylglycerol metabolic process;GO:0006641//triglyceride metabolic process;GO:0032048//cardiolipin metabolic process;GO:0046473//phosphatidic acid metabolic process;GO:0032502//developmental process gi|124486722|ref|NP_001074540.1|/0/lysocardiolipin acyltransferase 1 [Mus musculus] 70396 2319.2 31.70333333 32.45666667 0.033880306 Up 0.136823498 Asnsd1 asparagine synthetase domain containing 1 K06825|1|3e-27|126|gja:107110932|fibrillin 1 - "GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor" GO:0009064//glutamine family amino acid metabolic process;GO:0006528//asparagine metabolic process;GO:0009064//glutamine family amino acid metabolic process;GO:0006528//asparagine metabolic process gi|597436894|ref|NP_001277913.1|/1.70836e-78/asparagine synthetase domain-containing protein 1 isoform 2 [Mus musculus] 13722 1122 36.13666667 36.89 0.029766354 Up 0.136823498 Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 K15437|1|2e-151|537|mmu:13722|aminoacyl tRNA synthase complex-interacting multifunctional protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0031410//cytoplasmic vesicle;GO:0043234//protein complex;GO:0044421 GO:0005102//receptor binding;GO:0042802//identical protein binding;GO:0003723//RNA binding GO:0001525//angiogenesis;GO:0042221//response to chemical;GO:0012501//programmed cell death;GO:0006412//translation;GO:0001935//endothelial cell proliferation;GO:0007154//cell communication;GO:0022610;GO:0002252;GO:0019318//hexose metabolic process;GO:0006952//defense response gi|126012517|ref|NP_031952.2|/1.94809e-150/aminoacyl tRNA synthase complex-interacting multifunctional protein 1 [Mus musculus] 16178 1360 0.216666667 0.163333333 -0.407657969 Down 0.136738877 Il1r2 "interleukin 1 receptor, type II" K04387|1|0.0|783|mmu:16178|interleukin 1 receptor type II GO:0031224//intrinsic component of membrane GO:0004908//interleukin-1 receptor activity - gi|568905839|ref|XP_006495787.1|/0/PREDICTED: interleukin-1 receptor type 2 isoform X2 [Mus musculus] 216274 8006 0.17 0.223333333 0.393663848 Up 0.136738877 Cep290 centrosomal protein 290 K16533|1|0.0|4135|mmu:216274|centrosomal protein CEP290 - - - gi|163965444|ref|NP_666121.2|/0/centrosomal protein of 290 kDa [Mus musculus] 69885 1270 0.193333333 0.146666667 -0.398549376 Down 0.136738877 Aunip aurora kinase A and ninein interacting protein K16800|1|0.0|666|mmu:69885|aurora kinase A and ninein-interacting protein - - - gi|124487374|ref|NP_001074568.1|/0/aurora kinase A and ninein-interacting protein [Mus musculus] 80297 8737 0.153333333 0.203333333 0.407175382 Up 0.136738877 Sptbn4 "spectrin beta, non-erythrocytic 4" K06115|1|0.0|4152|rno:308458|spectrin beta GO:0016020//membrane;GO:0034399//nuclear periphery;GO:0070161;GO:0044297//cell body;GO:0016604//nuclear body;GO:0033267;GO:0030864//cortical actin cytoskeleton;GO:0016020//membrane;GO:0034399//nuclear periphery;GO:0070161;GO:0044297//cell body;GO:0016604//nuclear body;GO:0033267;GO:0030864//cortical actin cytoskeleton;GO:0016020//membrane;GO:0034399//nuclear periphery;GO:0070161;GO:0044297//cell body;GO:0016604//nuclear body;GO:0033267;GO:0030864//cortical actin cytoskeleton;GO:0016020//membrane;GO:0034399//nuclear periphery;GO:0070161;GO:0044297//cell body;GO:0016604//nuclear body;GO:0033267;GO:0030864//cortical actin cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0019899//enzyme binding;GO:0008092//cytoskeletal protein binding;GO:0019899//enzyme binding;GO:0008092//cytoskeletal protein binding;GO:0019899//enzyme binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0008289//lipid binding;GO:0019899//enzyme binding GO:0002027//regulation of heart rate;GO:0019953//sexual reproduction;GO:0007154//cell communication;GO:0050954//sensory perception of mechanical stimulus;GO:0001932//regulation of protein phosphorylation;GO:0090150//establishment of protein localization to membrane;GO:0035264//multicellular organism growth;GO:0045161//neuronal ion channel clustering;GO:0021955//central nervous system neuron axonogenesis;GO:0008344//adult locomotory behavior;GO:0002027//regulation of heart rate;GO:0019953//sexual reproduction;GO:0007154//cell communication;GO:0050954//sensory perception of mechanical stimulus;GO:0001932//regulation of protein phosphorylation;GO:0090150//establishment of protein localization to membrane;GO:0035264//multicellular organism growth;GO:0045161//neuronal ion channel clustering;GO:0021955//central nervous system neuron axonogenesis;GO:0008344//adult locomotory behavior;GO:0002027//regulation of heart rate;GO:0019953//sexual reproduction;GO:0007154//cell communication;GO:0050954//sensory perception of mechanical stimulus;GO:0001932//regulation of protein phosphorylation;GO:0090150//establishment of protein localization to membrane;GO:0035264//multicellular organism growth;GO:0045161//neuronal ion channel clustering;GO:0021955//central nervous system neuron axonogenesis;GO:0008344//adult locomotory behavior;GO:0002027//regulation of heart rate;GO:0030835//negative regulation of actin filament depolymerization;GO:0019953//sexual reproduction;GO:0007154//cell communication;GO:0050954//sensory perception of mechanical stimulus;GO:0001932//regulation of protein phosphorylation;GO:0006935//chemotaxis;GO:0090150//establishment of protein localization to membrane;GO:0035264//multicellular organism growth;GO:0045161//neuronal ion channel clustering;GO:0006814//sodium ion transport;GO:0021955//central nervous system neuron axonogenesis;GO:0008344//adult locomotory behavior "gi|148692241|gb|EDL24188.1|/0/spectrin beta 4, isoform CRA_a, partial [Mus musculus]" 234258 2271 0.173333333 0.226666667 0.387023123 Up 0.136738877 Neil3 nei like 3 (E. coli) K10569|1|0.0|1229|mmu:234258|endonuclease VIII-like 3 GO:0043231//intracellular membrane-bounded organelle "GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0046914//transition metal ion binding;GO:0043566//structure-specific DNA binding;GO:0016835//carbon-oxygen lyase activity" GO:0006281//DNA repair gi|22122759|ref|NP_666320.1|/0/endonuclease 8-like 3 [Mus musculus] 193217 3263 0.16 0.21 0.392317423 Up 0.136738877 BC018473 cDNA sequence BC018473 - - - - - 23965 10958.02 0.22 0.166666667 -0.40053793 Down 0.136738877 Tenm3 teneurin transmembrane protein 3 K06252|1|8e-64|250|lcm:102345859|tenascin GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464 GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity GO:0016337//single organismal cell-cell adhesion;GO:0010975//regulation of neuron projection development;GO:0007154//cell communication;GO:0016337//single organismal cell-cell adhesion;GO:0010975//regulation of neuron projection development;GO:0007154//cell communication gi|225543089|ref|NP_035987.3|/0/teneurin-3 isoform 1 [Mus musculus] 100045653 2564 0.213333333 0.163333333 -0.385290156 Down 0.136738877 Gm17769 "predicted gene, 17769" - - - - - 68926 4384 40.61666667 39.88 -0.026406435 Down 0.136663658 Ubap2 ubiquitin-associated protein 2 - - - - gi|27764457|gb|AAO23024.1|AF276965_1/0/lingerer protein-1 [Mus musculus] 76539 2035 3.546666667 3.706666667 0.063658637 Up 0.136626048 Fam204a "family with sequence similarity 204, member A" - - - - "gi|148669891|gb|EDL01838.1|/6.02755e-107/DNA segment, Chr 19, ERATO Doi 737, expressed, isoform CRA_d, partial [Mus musculus]" 79263 3070 4.01 4.166666667 0.055291452 Up 0.136626048 Trim39 tripartite motif-containing 39 K12015|1|0.0|966|mmu:79263|tripartite motif-containing protein 39 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003824//catalytic activity GO:0032446//protein modification by small protein conjugation;GO:0012501//programmed cell death;GO:0032446//protein modification by small protein conjugation;GO:0012501//programmed cell death gi|60360008|dbj|BAD90223.1|/0/mKIAA4179 protein [Mus musculus] 230257 6855 3.736666667 3.576666667 -0.063136202 Down 0.136626048 Ptbp3 polypyrimidine tract binding protein 3 K17844|1|0.0|995|ngi:103732537|polypyrimidine tract-binding protein 3 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0008380//RNA splicing;GO:0048469//cell maturation "gi|148670262|gb|EDL02209.1|/0/ROD1 regulator of differentiation 1 (S. pombe), isoform CRA_b, partial [Mus musculus]" 18126 3849.99 3.736666667 3.58 -0.061792285 Down 0.136626048 Nos2 "nitric oxide synthase 2, inducible" "K13241|1|0.0|2334|mmu:18126|nitric-oxide synthase, inducible [EC:1.14.13.39]" - - - - 16974 9368 3.936666667 4.1 0.058649351 Up 0.136626048 Lrp6 low density lipoprotein receptor-related protein 6 K03068|1|0.0|3112|mmu:16974|low density lipoprotein receptor-related protein 5/6 - - - gi|148727327|ref|NP_032540.2|/0/low-density lipoprotein receptor-related protein 6 precursor [Mus musculus] 76295 4883 3.81 3.97 0.05934801 Up 0.136626048 Atp11b "ATPase, class VI, type 11B" K01530|1|0.0|2278|mmu:76295|phospholipid-translocating ATPase [EC:3.6.3.1] GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0010008//endosome membrane GO:0032550;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0003824//catalytic activity GO:0044763;GO:0006811//ion transport;GO:0015914//phospholipid transport gi|37360160|dbj|BAC98058.1|/0/mKIAA0956 protein [Mus musculus] 12725 5310.41 3.833333333 3.676666667 -0.06020107 Down 0.136626048 Clcn3 "chloride channel, voltage-sensitive 3" K05012|1|0.0|1572|umr:103658150|chloride channel 3/4/5 GO:0031224//intrinsic component of membrane;GO:0030133//transport vesicle;GO:0044459;GO:0005770//late endosome;GO:0005769//early endosome;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0030133//transport vesicle;GO:0044459;GO:0005770//late endosome;GO:0005769//early endosome;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0030133//transport vesicle;GO:0044459;GO:0005770//late endosome;GO:0005769//early endosome;GO:0012505//endomembrane system GO:0032550;GO:0042802//identical protein binding;GO:0015291//secondary active transmembrane transporter activity;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0005254//chloride channel activity;GO:0032550;GO:0042802//identical protein binding;GO:0015291//secondary active transmembrane transporter activity;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0005254//chloride channel activity;GO:0032550;GO:0042802//identical protein binding;GO:0015291//secondary active transmembrane transporter activity;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0005254//chloride channel activity GO:0015698//inorganic anion transport;GO:0055067;GO:0034220//ion transmembrane transport;GO:0007032//endosome organization;GO:0015698//inorganic anion transport;GO:0055067;GO:0034220//ion transmembrane transport;GO:0007032//endosome organization;GO:0015698//inorganic anion transport;GO:0055067;GO:0034220//ion transmembrane transport;GO:0007032//endosome organization gi|41281837|ref|NP_776301.1|/0/H(+)/Cl(-) exchange transporter 3 isoform c [Mus musculus] 52348 6379 4.123333333 4.286666667 0.056045142 Up 0.136626048 Vps37a vacuolar protein sorting 37A K12185|1|0.0|657|mmu:52348|ESCRT-I complex subunit VPS37 GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen - GO:0045184//establishment of protein localization gi|31981032|ref|NP_291038.2|/0/vacuolar protein sorting-associated protein 37A [Mus musculus] 68212 808 42.08333333 41.35 -0.025361653 Down 0.136532025 Tmbim4 transmembrane BAX inhibitor motif containing 4 K06890|1|5e-120|432|mmu:68212|uncharacterized protein GO:0044431//Golgi apparatus part;GO:0031224//intrinsic component of membrane - GO:0019722//calcium-mediated signaling;GO:0006915//apoptotic process gi|21311865|ref|NP_080893.1|/3.83105e-119/protein lifeguard 4 [Mus musculus] 54391 2482 36.11666667 36.84666667 0.028869364 Up 0.136532025 Rfk riboflavin kinase K00861|1|1e-85|320|mmu:54391|riboflavin kinase [EC:2.7.1.26] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0032550;GO:0016301//kinase activity GO:0006771//riboflavin metabolic process gi|14149726|ref|NP_062310.1|/8.2416e-85/riboflavin kinase [Mus musculus] 100042939 318 0.01 0.043333333 2.115477217 Up 0.13651322 Gm14479 predicted gene 14479 K11251|1|7e-32|137|mmu:100042929|histone H2A GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0003676//nucleic acid binding GO:0044260;GO:0090304 gi|161333850|ref|NP_001104507.1|/6.67087e-31/histone cluster 2 family member [Mus musculus] 241118 2650 0.043333333 0.01 -2.115477217 Down 0.13651322 Asic4 acid-sensing (proton-gated) ion channel family member 4 K04831|1|0.0|938|tup:102489919|acid-sensing ion channel 4 GO:0031224//intrinsic component of membrane GO:0005261//cation channel activity GO:0006814//sodium ion transport gi|562882221|ref|XP_006168670.1|/0/PREDICTED: acid-sensing ion channel 4 [Tupaia chinensis] 22115 1403 0.01 0.04 2 Up 0.13651322 Tssk2 testis-specific serine kinase 2 K08811|1|0.0|715|mmu:22115|testis-specific serine kinase [EC:2.7.11.1] GO:0030141//secretory granule;GO:0005813//centrosome GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding GO:0006468//protein phosphorylation;GO:0048232//male gamete generation;GO:0007281//germ cell development gi|112734843|ref|NP_033462.2|/0/testis-specific serine/threonine-protein kinase 2 [Mus musculus] 667055 1593 0.04 0.01 -2 Down 0.13651322 Gm9992 predicted gene 9992 K16600|1|4e-166|587|gga:421566|tubulin polyglutamylase TTLL2 [EC:6.-.-.-];K02835|2|5e-12|75.1|cin:100181435|peptide chain release factor 1 GO:0031224//intrinsic component of membrane - - gi|187956197|gb|AAI47831.1|/0/Unc-93 homolog A (C. elegans) [Mus musculus] 278676 1461 0.01 0.04 2 Up 0.13651322 AY358078 cDNA sequence AY358078 "K03844|1|2e-21|106|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - gi|39930561|ref|NP_919328.1|/0/uncharacterized protein LOC278676 [Mus musculus] 19417 4243 0.01 0.04 2 Up 0.13651322 Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 K04349|1|0.0|2327|mmu:19417|Ras-specific guanine nucleotide-releasing factor 1 GO:0043005//neuron projection;GO:0044444//cytoplasmic part;GO:0043005//neuron projection;GO:0044444//cytoplasmic part GO:0005102//receptor binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0019900//kinase binding;GO:0005102//receptor binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0019900//kinase binding GO:0048167//regulation of synaptic plasticity;GO:0030030//cell projection organization;GO:0016601//Rac protein signal transduction;GO:0048167//regulation of synaptic plasticity;GO:0030030//cell projection organization;GO:0016601//Rac protein signal transduction gi|89111131|ref|NP_001034744.1|/5.87739e-84/ras-specific guanine nucleotide-releasing factor 1 isoform 2 [Mus musculus] 58803 1416 0.01 0.04 2 Up 0.13651322 Pga5 "pepsinogen 5, group I" K06002|1|0.0|791|mmu:58803|pepsin A [EC:3.4.23.1] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0044707 "gi|31981154|ref|NP_067428.2|/0/pepsinogen 5, group I precursor [Mus musculus]" 68870 1584 0.04 0.01 -2 Down 0.13651322 Ak8 adenylate kinase 8 K00939|1|0.0|972|mmu:68870|adenylate kinase [EC:2.7.4.3] GO:0044444//cytoplasmic part "GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0019201//nucleotide kinase activity;GO:0032550" GO:0006796//phosphate-containing compound metabolic process;GO:0006725//cellular aromatic compound metabolic process;GO:0007420//brain development gi|152963553|ref|NP_001029046.2|/0/adenylate kinase 8 [Mus musculus] 100043057 1538 0.01 0.04 2 Up 0.13651322 Tmem207 transmembrane protein 207 - - - - - 434960 1123 0.01 0.043333333 2.115477217 Up 0.13651322 Gm20747 "predicted gene, 20747" - - - - gi|68989247|ref|NP_001020412.1|/8.56604e-122/Ssty2 family member [Mus musculus] 19337 1183 0.01 0.043333333 2.115477217 Up 0.13651322 Rab33a "RAB33A, member RAS oncogene family" K07919|1|6e-148|526|nle:100606990|Ras-related protein Rab-33A - - - - 228858 2580 0.01 0.04 2 Up 0.13651322 Gdap1l1 ganglioside-induced differentiation-associated protein 1-like 1 - - - - "gi|148674381|gb|EDL06328.1|/0/ganglioside-induced differentiation-associated protein 1-like 1, partial [Mus musculus]" 20476 4019 0.01 0.04 2 Up 0.13651322 Six6 sine oculis-related homeobox 6 K19473|1|5e-125|452|rno:314221|homeobox protein SIX3/6 - - - - 72224 2468 0.01 0.043333333 2.115477217 Up 0.13651322 1700001J11Rik ring finger protein 19A pseudogene K11972|1|0.0|1234|mmu:30945|E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.27] GO:0031224//intrinsic component of membrane;GO:0043232 GO:0046914//transition metal ion binding;GO:0003824//catalytic activity - "gi|148676876|gb|EDL08823.1|/0/ring finger protein (C3HC4 type) 19, isoform CRA_a [Mus musculus]" 13115 2440 0.01 0.04 2 Up 0.13651322 Cyp27b1 "cytochrome P450, family 27, subfamily b, polypeptide 1" K07438|1|0.0|940|mmu:13115|25-hydroxyvitamin D3 1alpha-hydroxylase [EC:1.14.13.13] GO:0005740//mitochondrial envelope "GO:0046914//transition metal ion binding;GO:0046906//tetrapyrrole binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen" GO:0030278//regulation of ossification;GO:0055065//metal ion homeostasis;GO:0007589//body fluid secretion;GO:0006066//alcohol metabolic process;GO:0006694//steroid biosynthetic process;GO:0008283//cell proliferation;GO:0046683//response to organophosphorus;GO:0048545//response to steroid hormone;GO:0010979;GO:0034097//response to cytokine;GO:0043434//response to peptide hormone;GO:0001893//maternal placenta development;GO:0009967//positive regulation of signal transduction;GO:0010038//response to metal ion;GO:0070838//divalent metal ion transport;GO:0032769//negative regulation of monooxygenase activity;GO:0016049//cell growth;GO:0030216//keratinocyte differentiation;GO:0002237//response to molecule of bacterial origin;GO:0006706//steroid catabolic process;GO:0034694//response to prostaglandin gi|2443371|dbj|BAA22434.1|/0/25-hydroxyvitamin D3 1alpha-hydroxylase [Mus musculus] 170732 1340 0.01 0.043333333 2.115477217 Up 0.13651322 Trhr2 thyrotropin releasing hormone receptor 2 K04282|1|0.0|691|mmu:170732|thyrotropin-releasing hormone receptor GO:0031224//intrinsic component of membrane;GO:0044297//cell body GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007186//G-protein coupled receptor signaling pathway gi|18875348|ref|NP_573465.1|/0/thyrotropin releasing hormone receptor 2 [Mus musculus] 268534 2285 0.01 0.04 2 Up 0.13651322 Sntg2 "syntrophin, gamma 2" K00431|1|5e-129|464|ola:101156451|thyroid peroxidase [EC:1.11.1.8];K12196|2|6e-23|112|pps:100979126|vacuolar protein-sorting-associated protein 4;K12076|3|8e-10|68.6|api:100165774|disks large protein 1;K06095|4|4e-09|66.2|tad:TRIADDRAFT_27973|multiple PDZ domain protein;K19931|5|4e-09|66.2|tsp:Tsp_08398|protein lin-7 GO:0016020//membrane;GO:0043232 GO:0008289//lipid binding;GO:0019904//protein domain specific binding - gi|269973907|ref|NP_766539.2|/0/gamma-2-syntrophin [Mus musculus] 71897 2285 0.01 0.04 2 Up 0.13651322 Lypd6b LY6/PLAUR domain containing 6B K08576|1|1e-11|74.7|bfo:BRAFLDRAFT_132644|calpain-7 [EC:3.4.22.-] GO:0031224//intrinsic component of membrane - - gi|21313662|ref|NP_082266.1|/3.12375e-99/ly6/PLAUR domain-containing protein 6B precursor [Mus musculus] 252868 1289 0.01 0.043333333 2.115477217 Up 0.13651322 Odf4 outer dense fiber of sperm tails 4 "K18437|1|1e-19|100|myd:102754239|high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]" GO:0005929//cilium;GO:0044447;GO:0031224//intrinsic component of membrane - GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|21919408|ref|NP_665689.1|/2.73742e-146/outer dense fiber protein 4 [Mus musculus] 105463124 2766 0.01 0.04 2 Up 0.13651322 Borg BMP/OP-responsive gene - - - - - 20611 1285 0.01 0.043333333 2.115477217 Up 0.13651322 Ssty1 spermiogenesis specific transcript on the Y 1 - - - - gi|156766090|ref|NP_033246.2|/8.805e-121/Y-linked testis-specific protein 1 [Mus musculus] 332131 3434 0.01 0.04 2 Up 0.13651322 Krt78 keratin 78 "K07605|1|0.0|2041|mmu:332131|type II keratin, basic" - - - gi|145580629|ref|NP_997652.4|/0/keratin Kb40 [Mus musculus] 237362 1307 0.01 0.043333333 2.115477217 Up 0.13651322 Npffr1 neuropeptide FF receptor 1 K04240|1|0.0|733|mmu:237362|neuropeptide FF receptor 1 GO:0031224//intrinsic component of membrane GO:0008528//G-protein coupled peptide receptor activity;GO:0001664//G-protein coupled receptor binding GO:0071900//regulation of protein serine/threonine kinase activity;GO:0030817//regulation of cAMP biosynthetic process;GO:0000165//MAPK cascade gi|294661833|ref|NP_001170982.1|/0/neuropeptide FF receptor 1 [Mus musculus] 546134 1368 0.01 0.043333333 2.115477217 Up 0.13651322 Gramd2 GRAM domain containing 2 K19951|1|1e-08|63.9|nve:NEMVE_v1g176889|TBC1 domain family member 9 GO:0031224//intrinsic component of membrane - - gi|85702037|ref|NP_001028670.1|/3.17315e-180/GRAM domain-containing protein 2 [Mus musculus] 628951 1432 0.04 0.01 -2 Down 0.13651322 Gm6936 predicted gene 6936 - - - - - 271786 6966 0.01 0.04 2 Up 0.13651322 Galnt13 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 K00710|1|0.0|1115|mmu:271786|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008376//acetylgalactosaminyltransferase activity GO:0006493//protein O-linked glycosylation gi|617592859|ref|XP_007520941.1|/0/PREDICTED: polypeptide N-acetylgalactosaminyltransferase 13 [Erinaceus europaeus] 100862314 778 0.04 0.01 -2 Down 0.13651322 Gm21637 "predicted gene, 21637" - - - - gi|569010965|ref|XP_001476904.2|/7.90251e-135/PREDICTED: spindlin-2A-like [Mus musculus] 353237 5422 0.043333333 0.01 -2.115477217 Down 0.13651322 Pcdhac2 "protocadherin alpha subfamily C, 2" K16493|1|0.0|1818|mmu:353237|protocadherin alpha GO:0031224//intrinsic component of membrane - GO:0016337//single organismal cell-cell adhesion gi|51092283|ref|NP_001003672.1|/0/protocadherin alpha-C2 precursor [Mus musculus] 238057 1399 0.043333333 0.01 -2.115477217 Down 0.13651322 Gdf7 growth differentiation factor 7 K20013|1|1e-154|548|mmu:238057|growth differentiation factor 7 GO:0044421 GO:0005102//receptor binding;GO:0042802//identical protein binding "GO:0035990//tendon cell differentiation;GO:0001934//positive regulation of protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0001841//neural tube formation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0003006//developmental process involved in reproduction;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0021515//cell differentiation in spinal cord;GO:0030182//neuron differentiation" gi|33859664|ref|NP_038555.1|/7.80431e-158/growth/differentiation factor 7 isoform 2 precursor [Mus musculus] 244608 1271 0.01 0.04 2 Up 0.13651322 Ccdc113 coiled-coil domain containing 113 K14837|1|6e-26|120|tca:100142251|nucleolar protein 12;K20283|2|4e-07|58.5|obi:106872513|golgin subfamily A member 4;K10352|3|9e-06|53.9|aec:105151602|myosin heavy chain - - - gi|27370404|ref|NP_766502.1|/0/coiled-coil domain-containing protein 113 [Mus musculus] 270160 2971 0.01 0.04 2 Up 0.13651322 Rab39 "RAB39, member RAS oncogene family" K07924|1|5e-124|448|mmu:270160|Ras-related protein Rab-39A GO:0030139//endocytic vesicle;GO:0016020//membrane GO:0032550 GO:0035556//intracellular signal transduction;GO:0006906//vesicle fusion;GO:0051452//intracellular pH reduction;GO:0045184//establishment of protein localization gi|30425356|ref|NP_780771.1|/4.23127e-123/ras-related protein Rab-39A [Mus musculus] 76646 1210 0.01 0.04 2 Up 0.13651322 Wdr38 WD repeat domain 38 K19760|1|2e-40|169|sko:100369577|dynein assembly factor with WDR repeat domains 1 - - - gi|58037455|ref|NP_083963.1|/2.02883e-180/WD repeat-containing protein 38 [Mus musculus] 69376 1300 0.01 0.04 2 Up 0.13651322 Zpbp2 zona pellucida binding protein 2 - GO:0043234//protein complex;GO:0030141//secretory granule;GO:0043234//protein complex;GO:0030141//secretory granule;GO:0043234//protein complex;GO:0030141//secretory granule;GO:0043234//protein complex;GO:0044464 - GO:0035036//sperm-egg recognition;GO:0003006//developmental process involved in reproduction;GO:0035036//sperm-egg recognition;GO:0003006//developmental process involved in reproduction;GO:0035036//sperm-egg recognition;GO:0003006//developmental process involved in reproduction;GO:0035036//sperm-egg recognition;GO:0003006//developmental process involved in reproduction "gi|148684201|gb|EDL16148.1|/0/zona pellucida binding protein 2, isoform CRA_b, partial [Mus musculus]" 67758 1294 0.043333333 0.01 -2.115477217 Down 0.13651322 Aadac arylacetamide deacetylase (esterase) K13616|1|0.0|806|mmu:67758|arylacetamide deacetylase [EC:3.1.1.3] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0016298//lipase activity;GO:0052689//carboxylic ester hydrolase activity GO:0010896//regulation of triglyceride catabolic process "gi|148703424|gb|EDL35371.1|/0/arylacetamide deacetylase (esterase), isoform CRA_b, partial [Mus musculus]" 18587 2831 0.04 0.01 -2 Down 0.13651322 Pde6b "phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide" "K13756|1|0.0|1686|mmu:18587|rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [EC:3.1.4.35]" - "GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity" GO:0043010//camera-type eye development;GO:0009416//response to light stimulus;GO:0050953//sensory perception of light stimulus;GO:0006874//cellular calcium ion homeostasis;GO:0007154//cell communication;GO:0009150//purine ribonucleotide metabolic process "gi|113930735|ref|NP_032832.2|/0/rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta precursor [Mus musculus]" 100042929 318 0.01 0.043333333 2.115477217 Up 0.13651322 Gm14477 predicted gene 14477 K11251|1|7e-32|137|mmu:100042929|histone H2A GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0003676//nucleic acid binding GO:0044260;GO:0090304 gi|161333850|ref|NP_001104507.1|/6.67087e-31/histone cluster 2 family member [Mus musculus] 80720 1359 0.01 0.043333333 2.115477217 Up 0.13651322 Pbx4 pre B cell leukemia homeobox 4 K15611|1|0.0|648|mmu:80720|pre-B-cell leukemia transcription factor 4 GO:0043231//intracellular membrane-bounded organelle;GO:0000803//sex chromosome GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated" gi|68299791|ref|NP_001020125.1|/0/pre-B-cell leukemia transcription factor 4 [Mus musculus] 100038522 1385 0.01 0.043333333 2.115477217 Up 0.13651322 Dnmt3aos "DNA methyltransferase 3A, opposite strand" - - - - gi|74151690|dbj|BAE29640.1|/1.49665e-44/unnamed protein product [Mus musculus] 22165 2344 0.01 0.043333333 2.115477217 Up 0.13651322 Txk TXK tyrosine kinase K08016|1|0.0|1007|mmu:22165|tyrosine-protein kinase TXK [EC:2.7.10.2] GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0044212//transcription regulatory region DNA binding;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0044212//transcription regulatory region DNA binding;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0044212//transcription regulatory region DNA binding;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0044212//transcription regulatory region DNA binding GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0010863//positive regulation of phospholipase C activity;GO:0001819//positive regulation of cytokine production;GO:0006468//protein phosphorylation;GO:0046632//alpha-beta T cell differentiation;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0010863//positive regulation of phospholipase C activity;GO:0001819//positive regulation of cytokine production;GO:0006468//protein phosphorylation;GO:0046632//alpha-beta T cell differentiation;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0010863//positive regulation of phospholipase C activity;GO:0001819//positive regulation of cytokine production;GO:0006468//protein phosphorylation;GO:0046632//alpha-beta T cell differentiation;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0010863//positive regulation of phospholipase C activity;GO:0001819//positive regulation of cytokine production;GO:0006468//protein phosphorylation;GO:0046632//alpha-beta T cell differentiation "gi|148705885|gb|EDL37832.1|/0/TXK tyrosine kinase, isoform CRA_c, partial [Mus musculus]" 234857 2399 0.043333333 0.01 -2.115477217 Down 0.13651322 Spire2 spire homolog 2 (Drosophila) K02098|1|0.0|1273|mmu:234857|spire GO:0043232 GO:0008092//cytoskeletal protein binding GO:0051234//establishment of localization;GO:0007010//cytoskeleton organization gi|27151755|ref|NP_758491.1|/0/protein spire homolog 2 [Mus musculus] 243816 1152 0.01 0.043333333 2.115477217 Up 0.13651322 Gp6 glycoprotein 6 (platelet) K06264|1|8e-152|538|mmu:243816|platelet glycoprotein VI GO:0016021//integral component of membrane GO:0005515//protein binding;GO:0038023//signaling receptor activity GO:0007599//hemostasis;GO:0001775//cell activation;GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway gi|244793038|ref|NP_001156486.1|/6.96782e-151/platelet glycoprotein VI precursor [Mus musculus] 83430 1359 0.043333333 0.01 -2.115477217 Down 0.13651322 Il23a "interleukin 23, alpha subunit p19" "K05426|1|6e-102|373|mmu:83430|interleukin 23, alpha subunit p19" GO:0005615//extracellular space GO:0005126//cytokine receptor binding GO:0006954//inflammatory response;GO:0050691//regulation of defense response to virus by host;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0042742//defense response to bacterium;GO:0046635//positive regulation of alpha-beta T cell activation;GO:0001819//positive regulation of cytokine production;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0001866//NK T cell proliferation;GO:0042504;GO:0001787//natural killer cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0010534//regulation of activation of JAK2 kinase activity;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0010455//positive regulation of cell fate commitment;GO:0002824;GO:0001818//negative regulation of cytokine production;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0034103//regulation of tissue remodeling;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0042102//positive regulation of T cell proliferation gi|13752579|ref|NP_112542.1|/4.9459e-101/interleukin-23 subunit alpha precursor [Mus musculus] 74090 3500 0.043333333 0.01 -2.115477217 Down 0.13651322 Paqr5 progestin and adipoQ receptor family member V K17387|1|2e-60|237|gfr:102034408|kinesin family member 23;K07297|3|2e-16|91.3|aqu:100634009|adiponectin receptor GO:0031224//intrinsic component of membrane GO:0008289//lipid binding GO:0007292//female gamete generation;GO:0048869//cellular developmental process gi|58037337|ref|NP_083024.1|/0/membrane progestin receptor gamma [Mus musculus] 381544 1425 0.01 0.04 2 Up 0.13651322 Gm1661 predicted gene 1661 - - - - gi|85702083|ref|NP_001028946.1|/0/uncharacterized protein C1orf228 homolog isoform 2 [Mus musculus] 320718 3640 0.043333333 0.01 -2.115477217 Down 0.13651322 Slc26a9 "solute carrier family 26, member 9" "K14706|1|0.0|1545|mmu:320718|solute carrier family 26 (sulfate anion transporter), member 9" GO:0044459;GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity GO:0015698//inorganic anion transport;GO:0044763;GO:0055067;GO:0015711//organic anion transport gi|154090973|ref|NP_796217.2|/0/solute carrier family 26 member 9 [Mus musculus] 11499 2593 0.043333333 0.01 -2.115477217 Down 0.13651322 Adam5 a disintegrin and metallopeptidase domain 5 K16909|1|2e-173|612|mdo:100032987|disintegrin and metalloproteinase domain-containing protein 18 [EC:3.4.24.-] - - - - 332713 1409 0.04 0.01 -2 Down 0.13651322 BC051628 cDNA sequence BC051628 - - - - "gi|148675451|gb|EDL07398.1|/2.78235e-179/cDNA sequence BC051628, isoform CRA_b, partial [Mus musculus]" 19214 3187 0.01 0.043333333 2.115477217 Up 0.13651322 Ptgdr prostaglandin D receptor K04332|1|7e-175|617|mmu:19214|prostaglandin D2 receptor GO:0031224//intrinsic component of membrane GO:0004955//prostaglandin receptor activity GO:0006952//defense response;GO:0046128;GO:0006874//cellular calcium ion homeostasis;GO:0071379//cellular response to prostaglandin stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0007275//multicellular organism development;GO:0042311//vasodilation;GO:0043084//penile erection gi|225543126|ref|NP_032988.3|/5.69057e-174/prostaglandin D2 receptor [Mus musculus] 17986 1962 0.043333333 0.01 -2.115477217 Down 0.13651322 Ndp Norrie disease (pseudoglioma) (human) - GO:0044421 GO:0042802//identical protein binding;GO:0001664//G-protein coupled receptor binding "GO:0016055//Wnt signaling pathway;GO:0044767//single-organism developmental process;GO:0044093;GO:0006351//transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis" gi|6754808|ref|NP_035013.1|/5.62713e-62/norrin precursor [Mus musculus] 319983 1407 0.01 0.04 2 Up 0.13651322 9330111N05Rik RIKEN cDNA 9330111N05 gene - - - - - 217738 2526 0.043333333 0.01 -2.115477217 Down 0.13651322 Ism2 isthmin 2 - - - - - 226180 2272 0.01 0.043333333 2.115477217 Up 0.13651322 Ina "internexin neuronal intermediate filament protein, alpha" "K07608|1|3e-178|628|mmu:226180|internexin neuronal intermediate filament protein, alpha" GO:0005882//intermediate filament GO:0005488//binding GO:0045104//intermediate filament cytoskeleton organization;GO:0009888//tissue development gi|148539957|ref|NP_666212.3|/2.17299e-177/alpha-internexin [Mus musculus] 78809 3829 0.01 0.04 2 Up 0.13651322 4930562C15Rik RIKEN cDNA 4930562C15 gene K05855|1|5e-07|60.1|cfr:102521769|spleen tyrosine kinase [EC:2.7.10.2] - - - gi|222446622|ref|NP_084468.1|/0/uncharacterized protein C16orf96 homolog [Mus musculus] 240549 1515 0.01 0.04 2 Up 0.13651322 Gm4952 predicted gene 4952 K15517|1|4e-166|587|mmu:240549|glycine N-phenylacetyltransferase [EC:2.3.1.192] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016410//N-acyltransferase activity;GO:0016410//N-acyltransferase activity - gi|268835741|ref|NP_001013784.2|/3.48557e-165/glycine N-acyltransferase-like protein [Mus musculus] 215456 2636 0.01 0.04 2 Up 0.13651322 Gpat2 "glycerol-3-phosphate acyltransferase 2, mitochondrial" K00629|1|0.0|1399|mmu:215456|glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15] GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane GO:0016740//transferase activity GO:0006644//phospholipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0052646 gi|47847464|dbj|BAD21404.1|/0/mFLJ00202 protein [Mus musculus] 74851 778 0.04 0.01 -2 Down 0.13651322 Spin2-ps1 "spindlin family, member 2, pseudogene 1" - - - - gi|569010965|ref|XP_001476904.2|/3.92197e-134/PREDICTED: spindlin-2A-like [Mus musculus] 73542 1514 0.01 0.04 2 Up 0.13651322 Tssk5 testis-specific serine kinase 5 K08811|1|6e-53|211|nve:NEMVE_v1g212052|testis-specific serine kinase [EC:2.7.11.1] - GO:0043169//cation binding;GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|117676382|ref|NP_898922.2|/0/testis-specific serine/threonine-protein kinase 5 [Mus musculus] 66501 1343 0.043333333 0.01 -2.115477217 Down 0.13651322 1700029H14Rik RIKEN cDNA 1700029H14 gene - - - - gi|13385056|ref|NP_079877.1|/2.55601e-134/uncharacterized protein LOC66501 isoform 1 [Mus musculus] 105243 2490 0.043333333 0.01 -2.115477217 Down 0.13651322 Slc9a3 "solute carrier family 9 (sodium/hydrogen exchanger), member 3" "K12040|1|0.0|1488|mmu:105243|solute carrier family 9 (sodium/hydrogen exchanger), member 3" GO:0031224//intrinsic component of membrane;GO:0005903//brush border;GO:0044459 GO:0005451//monovalent cation:proton antiporter activity;GO:0005488//binding GO:0006814//sodium ion transport;GO:0006818//hydrogen transport;GO:0044763;GO:0048511//rhythmic process;GO:0031960//response to corticosteroid;GO:0006897//endocytosis;GO:0055067 gi|124486700|ref|NP_001074529.1|/0/sodium/hydrogen exchanger 3 precursor [Mus musculus] 547176 3365 0.01 0.04 2 Up 0.13651322 Zc3h12b zinc finger CCCH-type containing 12B K18668|1|0.0|1689|mmu:547176|ribonuclease ZC3H12 [EC:3.1.-.-] - - - - 106757 2565 0.043333333 0.01 -2.115477217 Down 0.13651322 Catsperd catsper channel auxiliary subunit delta K16895|1|0.0|1582|mmu:106757|cation channel sperm-associated protein subunit delta GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005891//voltage-gated calcium channel complex - GO:0048870//cell motility;GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|261245039|ref|NP_780559.2|/0/cation channel sperm-associated protein subunit delta precursor [Mus musculus] 72107 1327 0.01 0.043333333 2.115477217 Up 0.13651322 Dscc1 DNA replication and sister chromatid cohesion 1 K11271|1|0.0|747|mmu:72107|sister chromatid cohesion protein DCC1 - - - - 55925 1381.03 0.01 0.043333333 2.115477217 Up 0.13651322 Syt8 synaptotagmin VIII K19908|1|0.0|709|mmu:55925|synaptotagmin-8 GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic component of membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic component of membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic component of membrane;GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic component of membrane GO:0005543//phospholipid binding;GO:0000149//SNARE binding;GO:0005543//phospholipid binding;GO:0000149//SNARE binding;GO:0005543//phospholipid binding;GO:0000149//SNARE binding;GO:0005543//phospholipid binding;GO:0000149//SNARE binding GO:0051234//establishment of localization;GO:0007338//single fertilization;GO:0051234//establishment of localization;GO:0007338//single fertilization;GO:0051234//establishment of localization;GO:0007338//single fertilization;GO:0051234//establishment of localization;GO:0007338//single fertilization gi|551893787|ref|NP_001272790.1|/0/synaptotagmin-8 isoform c [Mus musculus] 321017 1599 0.01 0.04 2 Up 0.13651322 9230116L04Rik RIKEN cDNA 9230116L04 gene "K03858|1|2e-28|129|mmu:110417|phosphatidylinositol glycan, class H" GO:0044424 GO:0008375//acetylglucosaminyltransferase activity - gi|755542131|ref|XP_011242289.1|/3.81373e-42/PREDICTED: phosphatidylinositol N-acetylglucosaminyltransferase subunit H isoform X1 [Mus musculus] 70405 1426 0.01 0.04 2 Up 0.13651322 Calml3 calmodulin-like 3 K02183|1|1e-78|296|mmu:70405|calmodulin - GO:0046872//metal ion binding - gi|13386230|ref|NP_081692.1|/1.07253e-77/calmodulin-like protein 3 [Mus musculus] 22044 1400 0.04 0.01 -2 Down 0.13651322 Trh thyrotropin releasing hormone K05253|1|1e-126|455|mmu:22044|thyrotropin-releasing hormone "GO:0016020//membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0005179//hormone activity GO:0014047//glutamate secretion;GO:0050796//regulation of insulin secretion;GO:0006576//cellular biogenic amine metabolic process;GO:0051384//response to glucocorticoid;GO:0007165//signal transduction;GO:0009746;GO:0097305//response to alcohol;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0014051//gamma-aminobutyric acid secretion;GO:0008344//adult locomotory behavior gi|134031937|ref|NP_033452.2|/1.02877e-125/thyrotropin releasing hormone preproprotein [Mus musculus] 71223 1290 0.01 0.04 2 Up 0.13651322 Gpr15 G protein-coupled receptor 15 K08403|1|0.0|664|mmu:71223|G protein-coupled receptor 15 - - - - 20605 3869 0.043333333 0.01 -2.115477217 Down 0.13651322 Sstr1 somatostatin receptor 1 K04217|1|0.0|700|mmu:20605|somatostatin receptor 1 GO:0016021//integral component of membrane;GO:0044424 GO:0008188//neuropeptide receptor activity GO:0022037//metencephalon development;GO:0030098//lymphocyte differentiation;GO:0007267//cell-cell signaling;GO:0031667//response to nutrient levels;GO:0048232//male gamete generation;GO:0032355//response to estradiol;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0006950//response to stress gi|821394158|ref|XP_004270033.2|/0/PREDICTED: LOW QUALITY PROTEIN: somatostatin receptor type 1 [Orcinus orca] 225518 2601 0.01 0.04 2 Up 0.13651322 Prdm6 PR domain containing 6 K16459|1|3e-65|253|oaa:100076110|centrosomal protein CEP120;K04462|2|5e-31|139|myd:102766636|ecotropic virus integration site 1 protein - - - - 73608 1372 0.01 0.043333333 2.115477217 Up 0.13651322 Marveld3 MARVEL (membrane-associating) domain containing 3 - GO:0016020//membrane;GO:0043296//apical junction complex;GO:0043296//apical junction complex - GO:0034330;GO:0034330 gi|255708417|ref|NP_997612.2|/2.22311e-141/MARVEL domain-containing protein 3 isoform b [Mus musculus] 56538 1285 0.043333333 0.01 -2.115477217 Down 0.13651322 Klk11 kallikrein related-peptidase 11 K09620|1|6e-146|519|mmu:56538|kallikrein 11 [EC:3.4.21.-] - GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process gi|293651560|ref|NP_001170844.1|/5.14436e-145/kallikrein-11 isoform 1 precursor [Mus musculus] 70924 1463 0.043333333 0.01 -2.115477217 Down 0.13651322 4921511C10Rik RIKEN cDNA 4921511C10 gene - - - - "gi|148683518|gb|EDL15465.1|/1.20434e-31/mCG1032401, partial [Mus musculus]" 208666 2948 0.04 0.01 -2 Down 0.13651322 Diras1 "DIRAS family, GTP-binding RAS-like 1" "K07840|1|7e-107|391|cge:100765547|DIRAS family, GTP-binding Ras-like 1" GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process gi|344247042|gb|EGW03146.1|/4.21036e-107/GTP-binding protein Di-Ras1 [Cricetulus griseus] 78257 2520 0.01 0.04 2 Up 0.13651322 Lrrc9 leucine rich repeat containing 9 K16606|1|3e-24|117|apla:101795673|leucine-rich repeat-containing protein 49 - - - gi|218505686|ref|NP_084346.2|/0/leucine-rich repeat-containing protein 9 isoform 2 [Mus musculus] 100416830 1098 0.01 0.043333333 2.115477217 Up 0.13651322 Zfp572 zinc finger protein 572 K09230|1|1e-31|93.6|shr:100932558|SCAN domain-containing zinc finger protein - - - - 69117 1341 0.043333333 0.01 -2.115477217 Down 0.13651322 Adh6a alcohol dehydrogenase 6A (class V) K13951|1|4e-130|467|tgu:100222320|alcohol dehydrogenase 1/7 [EC:1.1.1.1] - - - gi|124286789|ref|NP_081221.1|/0/alcohol dehydrogenase 6A (class V) [Mus musculus] 74075 1462 0.04 0.01 -2 Down 0.13651322 Syce1 synaptonemal complex central element protein 1 K19534|1|2e-147|524|mmu:74075|synaptonemal complex central element protein 1 GO:0000795//synaptonemal complex GO:0043168//anion binding GO:0007129//synapsis gi|219555720|ref|NP_001137237.1|/1.92171e-146/synaptonemal complex central element protein 1 [Mus musculus] 67341 1157 0.01 0.043333333 2.115477217 Up 0.13651322 Ascl4 achaete-scute family bHLH transcription factor 4 K09067|1|5e-65|250|mmu:67341|achaete-scute complex protein - - - - 53324 2551 0.043333333 0.01 -2.115477217 Down 0.13651322 Nptx2 neuronal pentraxin 2 K11453|1|9e-119|430|amj:102562598|chromobox protein 6;K17495|5|1e-31|140|sko:100374227|CUB and sushi domain-containing protein - GO:0043169//cation binding GO:0007267//cell-cell signaling gi|7949098|ref|NP_058069.1|/0/neuronal pentraxin-2 precursor [Mus musculus] 100042946 318 0.01 0.043333333 2.115477217 Up 0.13651322 Gm14475 predicted gene 14475 K11251|1|7e-32|137|mmu:100042929|histone H2A GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0003676//nucleic acid binding GO:0044260;GO:0090304 gi|161333850|ref|NP_001104507.1|/6.67087e-31/histone cluster 2 family member [Mus musculus] 319433 1402 0.01 0.043333333 2.115477217 Up 0.13651322 Serpine3 "serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3" K16643|1|3e-44|182|pbi:103065925|glia-derived nexin - - - "gi|148704136|gb|EDL36083.1|/0/mCG10067, isoform CRA_b, partial [Mus musculus]" 320500 2276 0.01 0.043333333 2.115477217 Up 0.13651322 Tmem215 transmembrane protein 215 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|260274390|ref|NP_796149.2|/6.66072e-118/transmembrane protein 215 [Mus musculus] 100503184 1366 0.043333333 0.01 -2.115477217 Down 0.13651322 Gm19583 "predicted gene, 19583" - - - - "gi|148705935|gb|EDL37882.1|/1.1702e-41/mCG1046406, partial [Mus musculus]" 100041311 1306 0.01 0.043333333 2.115477217 Up 0.13651322 Gm11978 predicted gene 11978 K11837|1|1e-10|70.5|bfo:BRAFLDRAFT_121867|ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle - - gi|134053873|ref|NP_898911.2|/9.88747e-25/SCAN domain containing 3 [Mus musculus] 11495 2594 0.01 0.04 2 Up 0.13651322 Adam2 a disintegrin and metallopeptidase domain 2 K06833|1|0.0|1477|mmu:11495|disintegrin and metalloproteinase domain-containing protein 2 [EC:3.4.24.-] GO:0031224//intrinsic component of membrane;GO:0044464 GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0019538//protein metabolic process;GO:0022610;GO:0007632//visual behavior;GO:0048232//male gamete generation gi|116089327|ref|NP_033748.2|/0/disintegrin and metalloproteinase domain-containing protein 2 precursor [Mus musculus] 58188 1455 0.043333333 0.01 -2.115477217 Down 0.13651322 Vstm2b V-set and transmembrane domain containing 2B K03538|1|8e-33|144|tgu:100231396|ribonuclease P protein subunit POP4 [EC:3.1.26.5] - - - gi|10946730|ref|NP_067362.1|/3.7807e-94/V-set and transmembrane domain-containing protein 2B precursor [Mus musculus] 74472 1430 0.043333333 0.01 -2.115477217 Down 0.13651322 4933433C11Rik sperm tail PG rich repeat containing 3 - - - - gi|198278494|ref|NP_083237.1|/0/uncharacterized protein C9orf173 homolog [Mus musculus] 329496 3469 0.01 0.04 2 Up 0.13651322 Gm13986 predicted gene 13986 - - - - - 18302 2716 0.04 0.01 -2 Down 0.13651322 Oit3 oncoprotein induced transcript 3 K18274|1|8e-46|188|ecb:100051746|uromodulin;K19899|3|1e-45|187|mdo:100026204|pancreatic secretory granule membrane major glycoprotein GP2 GO:0012505//endomembrane system GO:0046872//metal ion binding - gi|27545185|ref|NP_035089.1|/0/oncoprotein-induced transcript 3 protein precursor [Mus musculus] 20132 1407 0.04 0.01 -2 Down 0.13651322 Rrh retinal pigment epithelium derived rhodopsin homolog K04253|1|0.0|649|mmu:20132|visual pigment-like receptor peropsin GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0050953//sensory perception of light stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0006464//cellular protein modification process gi|6677821|ref|NP_033128.1|/0/visual pigment-like receptor peropsin [Mus musculus] 73647 2346 0.01 0.04 2 Up 0.13651322 Capn9 calpain 9 K08578|1|0.0|1363|mmu:73647|calpain-9 [EC:3.4.22.-] GO:0044464 GO:0046872//metal ion binding;GO:0004197//cysteine-type endopeptidase activity GO:0019538//protein metabolic process;GO:0044707 gi|251823797|ref|NP_076198.2|/0/calpain-9 [Mus musculus] 100503584 2240 0.01 0.043333333 2.115477217 Up 0.13651322 Zfp534 zinc finger protein 534 K09228|1|0.0|1252|mmu:626316|KRAB domain-containing zinc finger protein - - - gi|187608657|ref|NP_001120660.1|/0/zinc finger protein 534 [Mus musculus] 100042931 318 0.01 0.043333333 2.115477217 Up 0.13651322 Gm14476 predicted gene 14476 K11251|1|7e-32|137|mmu:100042929|histone H2A GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0003676//nucleic acid binding GO:0044260;GO:0090304 gi|161333850|ref|NP_001104507.1|/6.67087e-31/histone cluster 2 family member [Mus musculus] 170733 1195 0.01 0.043333333 2.115477217 Up 0.13651322 Klra17 "killer cell lectin-like receptor, subfamily A, member 17" K17515|1|2e-13|79.3|cmy:102931345|C-type lectin domain family 9 member A;K17517|2|7e-13|77.4|myb:102251819|C-type lectin domain family 12 member B - - - "gi|568940920|ref|XP_006505727.1|/8.71097e-152/PREDICTED: killer cell lectin-like receptor, subfamily A, member 17 isoform X1 [Mus musculus]" 70843 1489 0.01 0.04 2 Up 0.13651322 Krt28 keratin 28 "K07604|1|0.0|790|mmu:70843|type I keratin, acidic" GO:0044424;GO:0043234//protein complex - - "gi|198278448|ref|NP_081850.1|/0/keratin, type I cytoskeletal 28 [Mus musculus]" 242285 1379 0.043333333 0.01 -2.115477217 Down 0.13651322 Sdr16c5 "short chain dehydrogenase/reductase family 16C, member 5" K15734|1|2e-167|590|mmu:242285|all-trans-retinol dehydrogenase (NAD+) [EC:1.1.1.105] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0036094//small molecule binding" GO:0001523//retinoid metabolic process;GO:0007601//visual perception;GO:0008283//cell proliferation gi|32526863|ref|NP_871789.1|/2.00419e-166/epidermal retinol dehydrogenase 2 [Mus musculus] 381933 1161 0.01 0.043333333 2.115477217 Up 0.13651322 6430531B16Rik RIKEN cDNA 6430531B16 gene K06540|1|2e-15|85.9|lve:103070000|disintegrin and metalloproteinase domain-containing protein 8 [EC:3.4.24.-] - - - gi|85701983|ref|NP_001028637.1|/2.73733e-179/uncharacterized protein LOC381933 [Mus musculus] 790913 1461 0.01 0.04 2 Up 0.13651322 Gm11413 predicted gene 11413 - - - - "gi|148699080|gb|EDL31027.1|/1.05505e-27/mCG144799, partial [Mus musculus]" 71153 1526 0.04 0.01 -2 Down 0.13651322 4933417O13Rik RIKEN cDNA 4933417O13 gene - - - - "gi|148686259|gb|EDL18206.1|/6.71097e-49/mCG145278, partial [Mus musculus]" 277468 2701 0.01 0.043333333 2.115477217 Up 0.13651322 Slc39a12 "solute carrier family 39 (zinc transporter), member 12" "K14718|1|0.0|1284|mmu:277468|solute carrier family 39 (zinc transporter), member 12" GO:0031224//intrinsic component of membrane GO:0008324//cation transmembrane transporter activity GO:0006812//cation transport;GO:0044763 gi|59858551|ref|NP_001012305.1|/0/zinc transporter ZIP12 precursor [Mus musculus] 66601 1366 0.043333333 0.01 -2.115477217 Down 0.13651322 Tmigd1 transmembrane and immunoglobulin domain containing 1 K06767|1|9e-13|77.4|pbi:103055779|Down syndrome cell adhesion molecule GO:0031224//intrinsic component of membrane - - gi|568975265|ref|XP_006534012.1|/1.29193e-149/PREDICTED: transmembrane and immunoglobulin domain-containing protein 1 isoform X4 [Mus musculus] 70941 2356 0.01 0.04 2 Up 0.13651322 4921539E11Rik RIKEN cDNA 4921539E11 gene - - - - gi|254588039|ref|NP_081888.1|/0/uncharacterized protein C1orf141 homolog isoform 1 [Mus musculus] 210762 1453 0.043333333 0.01 -2.115477217 Down 0.13651322 Ppp1r36 "protein phosphatase 1, regulatory subunit 36" K17575|1|0.0|751|mmu:210762|protein phosphatase 1 regulatory subunit 36 - GO:0019899//enzyme binding GO:0010921//regulation of phosphatase activity gi|251823783|ref|NP_001156575.1|/0/protein phosphatase 1 regulatory subunit 36 [Mus musculus] 231253 1454 0.04 0.01 -2 Down 0.13651322 9130230L23Rik RIKEN cDNA 9130230L23 gene - - - - - 14767 1218 0.01 0.04 2 Up 0.13651322 Nmur1 neuromedin U receptor 1 K05052|1|0.0|795|mmu:14767|neuromedin U receptor 1 GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0008188//neuropeptide receptor activity;GO:0008188//neuropeptide receptor activity GO:0010863//positive regulation of phospholipase C activity;GO:0007267//cell-cell signaling;GO:0019932//second-messenger-mediated signaling;GO:0015698//inorganic anion transport;GO:0070838//divalent metal ion transport;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006936//muscle contraction;GO:0010863//positive regulation of phospholipase C activity;GO:0007267//cell-cell signaling;GO:0019932//second-messenger-mediated signaling;GO:0015698//inorganic anion transport;GO:0070838//divalent metal ion transport;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006936//muscle contraction gi|984698622|ref|NP_001306156.1|/0/neuromedin-U receptor 1 isoform 1 [Mus musculus] 74635 1418 0.01 0.04 2 Up 0.13651322 4930425O10Rik RIKEN cDNA 4930425O10 gene - - - - "gi|148680141|gb|EDL12088.1|/1.14869e-39/mCG55273, partial [Mus musculus]" 620592 1416 0.01 0.04 2 Up 0.13651322 Tmem28 transmembrane protein 28 - GO:0031224//intrinsic component of membrane - - gi|124486869|ref|NP_001074752.1|/0/transmembrane protein FAM155B [Mus musculus] 229588 1470 0.01 0.04 2 Up 0.13651322 Gm128 predicted gene 128 - - - - gi|67625729|ref|NP_001020012.1|/1.69338e-142/protein MENT precursor [Mus musculus] 77383 2279 0.01 0.04 2 Up 0.13651322 C030029H02Rik RIKEN cDNA C030029H02 gene - - - - "gi|148685866|gb|EDL17813.1|/6.37621e-44/mCG144668, partial [Mus musculus]" 276920 1353 0.01 0.043333333 2.115477217 Up 0.13651322 Ccdc42 coiled-coil domain containing 42 K08501|1|1e-16|90.5|tgu:100217832|syntaxin 8;K11498|2|7e-07|57.8|dvi:Dvir_GJ13256|centromeric protein E - - - - 218030 2403 0.01 0.043333333 2.115477217 Up 0.13651322 Pou6f2 "POU domain, class 6, transcription factor 2" "K09368|1|0.0|704|mmu:218030|POU domain transcription factor, class 6" - - - - 433315 1432 0.01 0.04 2 Up 0.13651322 Gm13749 predicted gene 13749 - - - - gi|74217401|dbj|BAC38306.2|/2.04921e-52/unnamed protein product [Mus musculus] 212541 3249 0.01 0.04 2 Up 0.13651322 Rho rhodopsin K04250|1|0.0|679|mmu:212541|rhodopsin GO:0031224//intrinsic component of membrane;GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005789//endoplasmic reticulum membrane GO:0005501//retinoid binding;GO:0043169//cation binding;GO:0004888//transmembrane signaling receptor activity GO:0043010//camera-type eye development;GO:0050953//sensory perception of light stimulus;GO:0007602//phototransduction;GO:0006464//cellular protein modification process;GO:0007186//G-protein coupled receptor signaling pathway gi|21717805|ref|NP_663358.1|/0/rhodopsin [Mus musculus] 668101 1496 0.04 0.01 -2 Down 0.13651322 Sirpb1b signal-regulatory protein beta 1B K06551|1|0.0|702|mmu:668101|signal-regulatory protein alpha/beta1/gamma GO:0016020//membrane - GO:0006909//phagocytosis;GO:0007165//signal transduction gi|292781772|ref|NP_001166931.1|/0/signal-regulatory protein beta 1B [Mus musculus] 11827 1416 0.01 0.04 2 Up 0.13651322 Aqp2 aquaporin 2 K09865|1|7e-133|476|mmu:11827|aquaporin-2 GO:0032991//macromolecular complex;GO:0012506//vesicle membrane;GO:0030133//transport vesicle;GO:0030135//coated vesicle;GO:0031301//integral component of organelle membrane;GO:0000323//lytic vacuole;GO:0005783//endoplasmic reticulum;GO:0044459;GO:0010008//endosome membrane GO:0005372//water transmembrane transporter activity;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0015144//carbohydrate transmembrane transporter activity;GO:0022829//wide pore channel activity GO:0044703;GO:0046689//response to mercury ion;GO:0008643//carbohydrate transport;GO:0001656//metanephros development;GO:0009414//response to water deprivation;GO:0008154//actin polymerization or depolymerization;GO:0012501//programmed cell death;GO:0006816//calcium ion transport;GO:0003014//renal system process;GO:0048878//chemical homeostasis;GO:0043434//response to peptide hormone;GO:0006970//response to osmotic stress;GO:0046688//response to copper ion;GO:0019725//cellular homeostasis;GO:0002237//response to molecule of bacterial origin;GO:0042044//fluid transport gi|452120|gb|AAA41478.1|/2.39762e-138/unknown [Rattus norvegicus] 195564 3627 0.01 0.043333333 2.115477217 Up 0.13651322 Skint3 selection and upkeep of intraepithelial T cells 3 K06712|1|3e-58|228|myb:102252384|butyrophilin;K17270|2|7e-48|194|myd:107184767|myelin-oligodendrocyte glycoprotein GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|29243928|ref|NP_808246.1|/0/selection and upkeep of intraepithelial T-cells protein 3 isoform b precursor [Mus musculus] 18857 1364 0.01 0.043333333 2.115477217 Up 0.13651322 Pmp2 peripheral myelin protein 2 "K08753|1|5e-47|191|aam:106484618|fatty acid-binding protein 4, adipocyte" GO:0044424 GO:0032934//sterol binding GO:0051234//establishment of localization;GO:0016043//cellular component organization gi|71892436|ref|NP_001025476.1|/5.55525e-68/myelin P2 protein [Mus musculus] 94346 1282 0.01 0.043333333 2.115477217 Up 0.13651322 Tmem40 transmembrane protein 40 - - - - gi|755517575|ref|XP_011239812.1|/2.67944e-75/PREDICTED: transmembrane protein 40 isoform X3 [Mus musculus] 26439 2547 0.043333333 0.01 -2.115477217 Down 0.13651322 Psg19 pregnancy specific glycoprotein 19 K06499|1|1e-124|449|mmu:384557|carcinoembryonic antigen-related cell adhesion molecule - - - - 381738 2485 0.043333333 0.01 -2.115477217 Down 0.13651322 Drc1 dynein regulatory complex subunit 1 K19754|1|0.0|1224|mmu:381738|dynein regulatry complex protein 1 - - GO:0043623//cellular protein complex assembly;GO:0001539//cilium or flagellum-dependent cell motility gi|85701985|ref|NP_001028632.1|/0/dynein regulatory complex protein 1 [Mus musculus] 107626 1191 0.01 0.043333333 2.115477217 Up 0.13651322 Asmt acetylserotonin O-methyltransferase K00543|1|3e-171|603|mmu:107626|acetylserotonin N-methyltransferase [EC:2.1.1.4] - GO:0008171//O-methyltransferase activity;GO:0042802//identical protein binding GO:0051093//negative regulation of developmental process;GO:0030186//melatonin metabolic process gi|819231728|ref|NP_001295417.1|/8.31279e-171/acetylserotonin O-methyltransferase isoform 2 [Mus musculus] 216622 3274 0.04 0.01 -2 Down 0.13651322 4931440F15Rik RIKEN cDNA 4931440F15 gene K10349|1|1e-95|354|tru:101062979|Fem-1 homolog b GO:0044424 GO:0031862 GO:0006954//inflammatory response;GO:0031396//regulation of protein ubiquitination;GO:0043405//regulation of MAP kinase activity gi|34850070|ref|NP_789799.1|/0/protein fem-1 homolog A-B [Mus musculus] 74662 1433 0.04 0.01 -2 Down 0.13651322 4930448K20Rik glyceraldehyde-3-phosphate dehydrogenase pseudogene K00134|1|2e-95|226|rno:24383|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0015631//tubulin binding" GO:0007010//cytoskeleton organization;GO:0070997//neuron death;GO:0031647//regulation of protein stability;GO:0012501//programmed cell death;GO:0006412//translation;GO:0006007//glucose catabolic process;GO:0018119//peptidyl-cysteine S-nitrosylation;GO:0044710;GO:1901698//response to nitrogen compound;GO:0034341//response to interferon-gamma;GO:0032502//developmental process gi|55153885|gb|AAH85315.1|/8.50658e-95/Glyceraldehyde-3-phosphate dehydrogenase [Mus musculus] 232680 1354 0.01 0.043333333 2.115477217 Up 0.13651322 Cpa2 "carboxypeptidase A2, pancreatic" K01298|1|0.0|828|mmu:232680|carboxypeptidase A2 [EC:3.4.17.15] - - - - 75010 1446 0.01 0.04 2 Up 0.13651322 Tmbim7 transmembrane BAX inhibitor motif containing 7 K06890|1|8e-47|190|obi:106883014|uncharacterized protein GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|305855122|ref|NP_083430.1|/4.70741e-113/transmembrane BAX inhibitor motif containing 7 isoform a [Mus musculus] 14840 1235 0.01 0.04 2 Up 0.13651322 Gsg1 germ cell associated 1 K11167|1|2e-13|79.7|nle:100587094|dehydrogenase/reductase SDR family member 7C [EC:1.1.-.-] GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane GO:0019899//enzyme binding;GO:0019899//enzyme binding;GO:0019899//enzyme binding - gi|123317841|ref|NP_001074021.1|/0/germ cell-specific gene 1 protein isoform a [Mus musculus] 328258 1498 0.04 0.01 -2 Down 0.13651322 Slc25a48 "solute carrier family 25, member 48" "K15124|1|8e-162|572|mmu:328258|solute carrier family 25, member 48" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763 gi|254692847|ref|NP_808477.2|/6.36986e-161/solute carrier family 25 member 48 [Mus musculus] 22135 2265 0.01 0.043333333 2.115477217 Up 0.13651322 Tgoln2 trans-golgi network protein 2 K04490|1|4e-11|72.8|aam:106497459|transcription factor 7-like 1 - - - - 17136 2427 0.01 0.043333333 2.115477217 Up 0.13651322 Mag myelin-associated glycoprotein K06771|1|0.0|1158|rno:29409|myelin associated glycoprotein GO:0031224//intrinsic component of membrane;GO:0033267;GO:0043218//compact myelin - - gi|568944963|ref|XP_006539653.1|/0/PREDICTED: myelin-associated glycoprotein isoform X2 [Mus musculus] 71082 1520 0.04 0.01 -2 Down 0.13651322 4933416M07Rik RIKEN cDNA 4933416M07 gene K12484|1|4e-26|122|mmu:75767|Rab11 family-interacting protein 1/2/5 - - - - 223780 1300 0.01 0.043333333 2.115477217 Up 0.13651322 Adm2 adrenomedullin 2 - - - - - 329271 3337 0.01 0.043333333 2.115477217 Up 0.13651322 C230024C17Rik RIKEN cDNA C230024C17 gene - - - - - 67356 1187 0.01 0.043333333 2.115477217 Up 0.13651322 Tmco5 transmembrane and coiled-coil domains 5 - GO:0031224//intrinsic component of membrane - - "gi|148695941|gb|EDL27888.1|/2.84554e-150/transmembrane and coiled-coil domains 5, isoform CRA_b, partial [Mus musculus]" 16596 1534 0.04 0.01 -2 Down 0.13651322 Klf1 Kruppel-like factor 1 (erythroid) K09204|1|0.0|665|mmu:16596|krueppel-like factor 1 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding GO:0048469//cell maturation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043009//chordate embryonic development;GO:0030218//erythrocyte differentiation;GO:0016568//chromatin modification gi|225543580|ref|NP_034765.2|/0/Krueppel-like factor 1 [Mus musculus] 269902 2592 0.043333333 0.01 -2.115477217 Down 0.13651322 Vmn2r57 "vomeronasal 2, receptor 57" K04613|1|0.0|1335|mmu:637873|vomeronasal 2 receptor;K04612|2|0.0|1177|cge:100763896|calcium-sensing receptor - - - "gi|157278032|ref|NP_808432.2|/0/vomeronasal 2, receptor 57 precursor [Mus musculus]" 12617 3192 1.11 1.203333333 0.11647666 Up 0.136456805 Cenpc1 centromere protein C1 K11497|1|0.0|1657|mmu:12617|centromere protein C "GO:0000794//condensed nuclear chromosome;GO:0000775//chromosome, centromeric region" GO:0003676//nucleic acid binding GO:0034508//centromere complex assembly;GO:0000087//mitotic M phase gi|164698406|ref|NP_031709.2|/0/centromere protein C [Mus musculus] 20822 8736 1.14 1.05 -0.118644496 Down 0.136456805 Trove2 "TROVE domain family, member 2" K11089|1|0.0|1073|mmu:20822|60 kDa SS-A/Ro ribonucleoprotein GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex GO:0003676//nucleic acid binding GO:0048858//cell projection morphogenesis gi|7305523|ref|NP_038863.1|/0/60 kDa SS-A/Ro ribonucleoprotein [Mus musculus] 319758 8000 1.016666667 1.103333333 0.118021974 Up 0.136456805 Rfx7 "regulatory factor X, 7" K08061|1|2e-64|251|cmy:102932684|regulatory factor X 5 - - - gi|88703055|ref|NP_001028708.1|/0/DNA-binding protein RFX7 [Mus musculus] 76184 3615.78 1.163333333 1.07 -0.120653739 Down 0.136456805 Abca6 "ATP-binding cassette, sub-family A (ABC1), member 6" "K05649|1|0.0|703|mmu:76184|ATP-binding cassette, subfamily A (ABC1), member 6" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0051234//establishment of localization;GO:0051234//establishment of localization;GO:0051234//establishment of localization gi|262118234|ref|NP_001160028.1|/0/ATP-binding cassette sub-family A member 6 isoform 2 [Mus musculus] 59005 634 31.77666667 32.49333333 0.032175955 Up 0.136447403 Trappc2l trafficking protein particle complex 2-like K20301|1|3e-76|286|ngi:103740003|trafficking protein particle complex subunit 2 GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle - GO:0016482//cytosolic transport gi|675682493|ref|XP_003805818.2|/2.60557e-75/PREDICTED: trafficking protein particle complex subunit 2-like protein isoform X2 [Pan paniscus] 227095 1838 30.50333333 29.78333333 -0.034461677 Down 0.136447403 Hibch 3-hydroxyisobutyryl-Coenzyme A hydrolase K05605|1|0.0|728|mmu:227095|3-hydroxyisobutyryl-CoA hydrolase [EC:3.1.2.4] - - - - 22017 2715 1.646666667 1.756666667 0.09329192 Up 0.136428598 Tpmt thiopurine methyltransferase K00569|1|8e-129|464|mmu:22017|thiopurine S-methyltransferase [EC:2.1.1.67] GO:0044424 GO:0008172//S-methyltransferase activity GO:0008152//metabolic process;GO:0048545//response to steroid hormone gi|568982501|ref|XP_006516988.1|/3.41838e-140/PREDICTED: thiopurine S-methyltransferase isoform X6 [Mus musculus] 23886 1084 1.763333333 1.656666667 -0.090021871 Down 0.136428598 Gdf15 growth differentiation factor 15 K05504|1|1e-130|468|mmu:23886|growth differentiation factor 15 GO:0044421 GO:0005102//receptor binding - gi|170784848|ref|NP_035949.2|/1.04852e-129/growth/differentiation factor 15 precursor [Mus musculus] 65257 3225 1.72 1.613333333 -0.092364018 Down 0.136428598 Asb3 ankyrin repeat and SOCS box-containing 3 K10325|1|0.0|1037|mmu:65257|ankyrin repeat and SOCS box protein 3 - - - gi|114205426|ref|NP_076395.2|/0/ankyrin repeat and SOCS box protein 3 [Mus musculus] 71492 2598 1.736666667 1.85 0.091204399 Up 0.136428598 Bbs7 Bardet-Biedl syndrome 7 (human) K16749|1|0.0|1382|mmu:71492|Bardet-Biedl syndrome 7 protein GO:0005815//microtubule organizing center;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane - GO:0030154//cell differentiation;GO:0007417//central nervous system development;GO:0007166//cell surface receptor signaling pathway;GO:0033036;GO:0048736 "gi|148703141|gb|EDL35088.1|/0/Bardet-Biedl syndrome 7, isoform CRA_f, partial [Mus musculus]" 106248 2838 1.85 1.963333333 0.085779863 Up 0.136428598 Qtrtd1 queuine tRNA-ribosyltransferase domain containing 1 K15407|1|0.0|707|mmu:106248|queuine tRNA-ribosyltransferase subunit QTRTD1 [EC:2.4.2.29] GO:0043231//intracellular membrane-bounded organelle "GO:0016763//transferase activity, transferring pentosyl groups;GO:0046914//transition metal ion binding" GO:0006400//tRNA modification gi|54144622|ref|NP_083404.2|/0/queuine tRNA-ribosyltransferase subunit QTRTD1 [Mus musculus] 107182 8509 1.733333333 1.626666667 -0.091630475 Down 0.136428598 Btaf1 B-TFIID TATA-box binding protein associated factor 1 K15192|1|0.0|3444|mmu:107182|TATA-binding protein-associated factor [EC:3.6.4.-] - - - - 791294 1506 0.203333333 0.156666667 -0.376148486 Down 0.136409794 Gm9958 predicted gene 9958 - - - - gi|148673376|gb|EDL05323.1|/3.6395e-39/mCG147145 [Mus musculus] 64707 4136 0.153333333 0.2 0.38332864 Up 0.136409794 Suv39h2 suppressor of variegation 3-9 homolog 2 (Drosophila) K11419|1|0.0|732|mmu:64707|histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43] GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin GO:0046914//transition metal ion binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0046914//transition metal ion binding;GO:0018024//histone-lysine N-methyltransferase activity "GO:0048869//cellular developmental process;GO:0034968//histone lysine methylation;GO:0007126//meiotic nuclear division;GO:0006351//transcription, DNA-templated;GO:0048869//cellular developmental process;GO:0034968//histone lysine methylation;GO:0006351//transcription, DNA-templated" gi|31543790|ref|NP_073561.2|/0/histone-lysine N-methyltransferase SUV39H2 [Mus musculus] 433107 663 0.156666667 0.203333333 0.376148486 Up 0.136409794 Esp6 exocrine gland secreted peptide 6 - GO:0044421 GO:0005102//receptor binding GO:0045924//regulation of female receptivity gi|294712521|ref|NP_001171000.1|/2.54978e-71/exocrine gland-secreting peptide 6 precursor [Mus musculus] 16430 2697 11.7 11.40666667 -0.036631271 Down 0.136409794 Stt3a "STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)" K07151|1|0.0|1449|cge:100751391|dolichyl-diphosphooligosaccharide--protein glycosyltransferase [EC:2.4.99.18] GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane GO:0004576//oligosaccharyl transferase activity GO:0006487//protein N-linked glycosylation gi|568958903|ref|XP_006510101.1|/0/PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A isoform X1 [Mus musculus] 53791 3199 0.216666667 0.166666667 -0.378511623 Down 0.136409794 Tlr5 toll-like receptor 5 K10168|1|0.0|1607|mmu:53791|toll-like receptor 5 - - - - 319247 1197 0.203333333 0.156666667 -0.376148486 Down 0.136409794 9530080O11Rik RIKEN cDNA 9530080O11 gene - - - - - 70730 1133 0.353333333 0.416666667 0.23786383 Up 0.136353379 6330409D20Rik RIKEN cDNA 6330409D20 gene - - - - "gi|148676625|gb|EDL08572.1|/1.49738e-81/mCG145914, partial [Mus musculus]" 13723 2622 0.353333333 0.416666667 0.23786383 Up 0.136353379 Emb embigin K06535|1|1e-10|71.6|pss:102461411|basigin GO:0031224//intrinsic component of membrane - - gi|226437629|ref|NP_034460.3|/2.4215e-167/embigin precursor [Mus musculus] 331547 3290 0.31 0.366666667 0.242200902 Up 0.136353379 A230072E10Rik RIKEN cDNA A230072E10 gene K08867|1|3e-59|233|mmu:279561|WNK lysine deficient protein kinase [EC:2.7.11.1] - - - - 20286 5958 36.74333333 36.03 -0.028283861 Down 0.13631577 Zc3h7b zinc finger CCCH type containing 7B K17766|1|9e-11|73.2|ptg:102954436|mitochondrial import receptor subunit TOM34 - - - gi|755551252|ref|XP_011243828.1|/0/PREDICTED: zinc finger CCCH domain-containing protein 7B isoform X1 [Mus musculus] 74018 6074.88 2.133333333 2.016666667 -0.081136763 Down 0.136306367 Als2 amyotrophic lateral sclerosis 2 (juvenile) K04575|1|0.0|3197|mmu:74018|amyotrophic lateral sclerosis 2 protein GO:0032991//macromolecular complex;GO:0031252//cell leading edge;GO:0044327//dendritic spine head;GO:0005815//microtubule organizing center;GO:0044297//cell body;GO:0005768//endosome;GO:0032991//macromolecular complex;GO:0031252//cell leading edge;GO:0044327//dendritic spine head;GO:0005815//microtubule organizing center;GO:0044297//cell body;GO:0005768//endosome;GO:0032991//macromolecular complex;GO:0031252//cell leading edge;GO:0044327//dendritic spine head;GO:0005815//microtubule organizing center;GO:0044297//cell body;GO:0005768//endosome GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0017048//Rho GTPase binding;GO:0042802//identical protein binding;GO:0030295//protein kinase activator activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0017048//Rho GTPase binding;GO:0042802//identical protein binding;GO:0030295//protein kinase activator activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0017048//Rho GTPase binding;GO:0042802//identical protein binding;GO:0030295//protein kinase activator activity GO:0006996//organelle organization;GO:0043009//chordate embryonic development;GO:0002209//behavioral defense response;GO:0031175//neuron projection development;GO:0044708//single-organism behavior;GO:0007270//neuron-neuron synaptic transmission;GO:0048741//skeletal muscle fiber development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007034//vacuolar transport;GO:0051259//protein oligomerization;GO:0032535//regulation of cellular component size;GO:0033036;GO:0045860//positive regulation of protein kinase activity;GO:0006996//organelle organization;GO:0043009//chordate embryonic development;GO:0002209//behavioral defense response;GO:0031175//neuron projection development;GO:0044708//single-organism behavior;GO:0007270//neuron-neuron synaptic transmission;GO:0048741//skeletal muscle fiber development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007034//vacuolar transport;GO:0051259//protein oligomerization;GO:0032535//regulation of cellular component size;GO:0033036;GO:0045860//positive regulation of protein kinase activity;GO:0006996//organelle organization;GO:0043009//chordate embryonic development;GO:0002209//behavioral defense response;GO:0031175//neuron projection development;GO:0044708//single-organism behavior;GO:0007270//neuron-neuron synaptic transmission;GO:0048741//skeletal muscle fiber development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007034//vacuolar transport;GO:0051259//protein oligomerization;GO:0032535//regulation of cellular component size;GO:0033036;GO:0045860//positive regulation of protein kinase activity "gi|148667706|gb|EDL00123.1|/0/amyotrophic lateral sclerosis 2 (juvenile) homolog (human), isoform CRA_a, partial [Mus musculus]" 73068 3344 2.173333333 2.296666667 0.079632018 Up 0.136306367 Fut11 fucosyltransferase 11 K11257|1|0.0|870|mmu:73068|galactoside 3-L-fucosyltransferase 11 [EC:2.4.1.-] GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane GO:0008417//fucosyltransferase activity GO:0006464//cellular protein modification process;GO:0070085//glycosylation "gi|58037305|ref|NP_082704.1|/0/alpha-(1,3)-fucosyltransferase 11 precursor [Mus musculus]" 216238 7836 2.29 2.173333333 -0.075438135 Down 0.136306367 Eea1 early endosome antigen 1 K12478|1|0.0|2211|mmu:216238|early endosome antigen 1 GO:0005768//endosome;GO:0043234//protein complex;GO:0019898//extrinsic component of membrane GO:0042802//identical protein binding;GO:0035091//phosphatidylinositol binding;GO:0046914//transition metal ion binding GO:0016192//vesicle-mediated transport gi|50053824|ref|NP_001001932.1|/0/early endosome antigen 1 [Mus musculus] 71640 3416.67 2.076666667 2.193333333 0.078855421 Up 0.136306367 Zfp949 zinc finger protein 949 K09228|1|0.0|1294|mmu:71640|KRAB domain-containing zinc finger protein - GO:0043169//cation binding;GO:0043169//cation binding - gi|219283262|ref|NP_001136415.1|/0/uncharacterized protein LOC71640 [Mus musculus] 56220 4680 2.106666667 2.23 0.082081652 Up 0.136306367 Zfp386 zinc finger protein 386 (Kruppel-like) K09228|1|0.0|1256|mmu:56220|KRAB domain-containing zinc finger protein GO:0044464;GO:0044464;GO:0044464 GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding "GO:0048232//male gamete generation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048232//male gamete generation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048232//male gamete generation;GO:0045892//negative regulation of transcription, DNA-templated" gi|60360596|dbj|BAD90318.1|/0/mKIAA4205 protein [Mus musculus] 234413 2718 2.213333333 2.336666667 0.078231203 Up 0.136306367 Zfp961 zinc finger protein 961 K09228|1|0.0|930|mmu:234413|KRAB domain-containing zinc finger protein - - - gi|257196138|ref|NP_001158053.1|/0/uncharacterized protein LOC234413 [Mus musculus] 242570 4006 2.203333333 2.326666667 0.078576765 Up 0.136306367 Raver2 "ribonucleoprotein, PTB-binding 2" K11219|1|4e-64|249|fch:102058589|non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2];K13208|2|4e-08|63.9|xma:102222278|ELAV like protein 2/3/4 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding - gi|33942106|ref|NP_898845.1|/0/ribonucleoprotein PTB-binding 2 [Mus musculus] 24127 10266.14 2.3 2.423333333 0.075359002 Up 0.136306367 Xrn1 5'-3' exoribonuclease 1 K12618|1|0.0|3233|mmu:24127|5'-3' exoribonuclease 1 [EC:3.1.13.-] - - - - 217232 5780.35 2.15 2.03 -0.082856932 Down 0.136306367 Cdc27 cell division cycle 27 K03350|1|0.0|1295|mmu:217232|anaphase-promoting complex subunit 3 GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen;GO:0005819//spindle;GO:0000152//nuclear ubiquitin ligase complex;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0000152//nuclear ubiquitin ligase complex;GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen;GO:0005819//spindle;GO:0000152//nuclear ubiquitin ligase complex;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0000152//nuclear ubiquitin ligase complex GO:0019902//phosphatase binding;GO:0019902//phosphatase binding;GO:0019902//phosphatase binding;GO:0019902//phosphatase binding GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0007067//mitotic nuclear division;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0007067//mitotic nuclear division;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0007067//mitotic nuclear division;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0007067//mitotic nuclear division gi|553727148|ref|NP_001272919.1|/0/cell division cycle protein 27 homolog isoform 4 [Mus musculus] 330319 4177.61 35.93 35.23333333 -0.028247964 Down 0.136212343 Wipf3 "WAS/WASL interacting protein family, member 3" K19475|1|3e-134|482|mmu:330319|WAS/WASL-interacting protein - GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding - gi|268607520|ref|NP_001161332.1|/1.16313e-161/WAS/WASL-interacting protein family member 3 isoform a [Mus musculus] 320135 1141 0.173333333 0.223333333 0.365649472 Up 0.136212343 BC049715 cDNA sequence BC049715 - - - - gi|119392079|ref|NP_848891.2|/2.87979e-133/uncharacterized protein C12orf60 homolog [Mus musculus] 233912 3852 5.976666667 6.173333333 0.04670861 Up 0.136174734 Armc5 armadillo repeat containing 5 - - - - gi|47847378|dbj|BAD21361.1|/0/mFLJ00019 protein [Mus musculus] 72141 2499 5.43 5.633333333 0.053036643 Up 0.136174734 Adpgk ADP-dependent glucokinase K08074|1|0.0|922|mmu:72141|ADP-dependent glucokinase [EC:2.7.1.147] - GO:0043169//cation binding;GO:0016301//kinase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006007//glucose catabolic process "gi|148694017|gb|EDL25964.1|/0/ADP-dependent glucokinase, isoform CRA_b, partial [Mus musculus]" 75669 4884 6.373333333 6.173333333 -0.045998425 Down 0.136174734 Pik3r4 "phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150" "K08333|1|0.0|2687|mmu:75669|phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]" GO:0005768//endosome GO:0004672//protein kinase activity;GO:0032550 - gi|124486789|ref|NP_001074778.1|/0/phosphoinositide 3-kinase regulatory subunit 4 [Mus musculus] 84036 4042 5.34 5.143333333 -0.054136086 Down 0.136174734 Kcnn1 "potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1" K04942|1|0.0|947|mmu:84036|potassium intermediate/small conductance calcium-activated channel subfamily N member 1 - - - - 14761 1140 5.133333333 5.33 0.054239588 Up 0.136174734 Gpr27 G protein-coupled receptor 27 K04301|1|6e-128|459|rno:65275|G protein-coupled receptor 27 GO:0016020//membrane - GO:0007154//cell communication gi|12831217|ref|NP_075587.1|/5.28279e-127/probable G-protein coupled receptor 27 [Rattus norvegicus] 100715 1873 5.443333333 5.243333333 -0.05400612 Down 0.136174734 Papd4 PAP associated domain containing 4 K14079|1|0.0|950|mmu:100715|poly(A) RNA polymerase GLD2 [EC:2.7.7.19] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0032550;GO:0070566//adenylyltransferase activity GO:0031123//RNA 3'-end processing;GO:0000956//nuclear-transcribed mRNA catabolic process gi|19527122|ref|NP_598666.1|/0/poly(A) RNA polymerase GLD2 [Mus musculus] 17997 3542 5.743333333 5.94 0.048574635 Up 0.136174734 Nedd1 "neural precursor cell expressed, developmentally down-regulated gene 1" K16547|1|0.0|1272|mmu:17997|protein NEDD1 GO:0005819//spindle;GO:0000242//pericentriolar material - GO:0031109//microtubule polymerization or depolymerization;GO:0032880//regulation of protein localization;GO:0044772//mitotic cell cycle phase transition;GO:0000087//mitotic M phase gi|568966904|ref|XP_006513397.1|/0/PREDICTED: protein NEDD1 isoform X1 [Mus musculus] 70345 1523 1.343333333 1.44 0.100251474 Up 0.13611832 0610038B21Rik RIKEN cDNA 0610038B21 gene K13736|1|2e-22|109|mmu:78514|Rho GTPase-activating protein 10 GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0008289//lipid binding GO:0006996//organelle organization;GO:0006915//apoptotic process;GO:0007264//small GTPase mediated signal transduction gi|148678896|gb|EDL10843.1|/4.69266e-26/mCG147357 [Mus musculus] 243833 3850 1.36 1.456666667 0.099064128 Up 0.13611832 Zfp128 zinc finger protein 128 K09228|1|0.0|1199|mmu:243833|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding "GO:0006351//transcription, DNA-templated;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway" gi|24418923|ref|NP_722497.1|/0/zinc finger protein 8 [Mus musculus] 67200 2546.02 1.343333333 1.44 0.100251474 Up 0.13611832 Ccdc77 coiled-coil domain containing 77 K16757|1|3e-113|307|mmu:67200|coiled-coil domain-containing protein 77 GO:0005815//microtubule organizing center;GO:0005815//microtubule organizing center - - gi|755517193|ref|XP_011239738.1|/3.63427e-175/PREDICTED: coiled-coil domain-containing protein 77 isoform X4 [Mus musculus] 269997 2684 1.413333333 1.516666667 0.101802281 Up 0.13611832 Zfp747 zinc finger protein 747 K09228|1|0.0|884|mmu:269997|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|30425352|ref|NP_780769.1|/0/zinc finger protein 747 [Mus musculus] 227674 3328 1.333333333 1.43 0.100977648 Up 0.13611832 Ddx31 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 31 K14806|1|0.0|1359|mmu:227674|ATP-dependent RNA helicase DDX31/DBP7 [EC:3.6.4.13] - - - - 14664 3272 1.553333333 1.453333333 -0.09600182 Down 0.13611832 Slc6a9 "solute carrier family 6 (neurotransmitter transporter, glycine), member 9" "K05038|1|0.0|1275|mmu:14664|solute carrier family 6 (neurotransmitter transporter, amino acid) member 5/7/9/14" GO:0016021//integral component of membrane GO:0005488//binding;GO:0005343//organic acid:sodium symporter activity;GO:0005326//neurotransmitter transporter activity GO:0046942//carboxylic acid transport;GO:0006812//cation transport "gi|148698593|gb|EDL30540.1|/0/solute carrier family 6 (neurotransmitter transporter, glycine), member 9, isoform CRA_a, partial [Mus musculus]" 66707 1455 0.243333333 0.19 -0.356934545 Down 0.13608071 Nkapl NFKB activating protein-like K09229|1|7e-67|257|oas:105603790|KRAB and SCAN domains-containing zinc finger protein - - - gi|254553396|ref|NP_079995.2|/4.77152e-97/NKAP-like protein [Mus musculus] 15002 2670 0.163333333 0.21 0.362570079 Up 0.13608071 H2-Ob "histocompatibility 2, O region beta locus" "K06752|1|3e-145|518|mmu:15002|major histocompatibility complex, class II" GO:0042611;GO:0031224//intrinsic component of membrane;GO:0000323//lytic vacuole - GO:0002376//immune system process "gi|29788774|ref|NP_034519.2|/2.25121e-144/histocompatibility 2, O region beta locus precursor [Mus musculus]" 623796 2231 0.186666667 0.24 0.362570079 Up 0.13608071 Gm12504 prothymosin alpha pseudogene - - - - "gi|795575070|ref|XP_011722227.1|/1.54351e-10/PREDICTED: prothymosin alpha-like, partial [Macaca nemestrina]" 80290 4068.74 35.89666667 36.58666667 0.027468098 Up 0.136061905 Gpr146 G protein-coupled receptor 146 K08431|1|1e-178|630|mmu:80290|G protein-coupled receptor 146 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway gi|31981402|ref|NP_084534.2|/8.72226e-178/probable G-protein coupled receptor 146 isoform 1 [Mus musculus] 66593 1939 36.06666667 36.76 0.027470673 Up 0.136061905 Diablo "diablo, IAP-binding mitochondrial protein" K10522|1|6e-128|460|mmu:66593|diablo - - - - 12331 2754.25 28.60666667 29.3 0.034549264 Up 0.136061905 Cap1 "CAP, adenylate cyclase-associated protein 1 (yeast)" K17261|1|0.0|873|mmu:12331|adenylyl cyclase-associated protein GO:0016020//membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0016477//cell migration;GO:0007010//cytoskeleton organization;GO:0032989;GO:0006897//endocytosis;GO:0016477//cell migration;GO:0007010//cytoskeleton organization;GO:0032989;GO:0006897//endocytosis "gi|148698452|gb|EDL30399.1|/0/CAP, adenylate cyclase-associated protein 1 (yeast), isoform CRA_b, partial [Mus musculus]" 16985 1907.95 29.79333333 29.11666667 -0.033144342 Down 0.135902065 Lsp1 lymphocyte specific 1 K14957|1|1e-140|503|mmu:16985|lymphocyte-specific protein 1 GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane;GO:0016020//membrane GO:0060089;GO:0060089;GO:0060089;GO:0060089;GO:0060089;GO:0060089 GO:0006950//response to stress;GO:0042221//response to chemical;GO:0012501//programmed cell death;GO:0006996//organelle organization;GO:0007154//cell communication;GO:0006950//response to stress;GO:0042221//response to chemical;GO:0012501//programmed cell death;GO:0006996//organelle organization;GO:0007154//cell communication;GO:0006950//response to stress;GO:0042221//response to chemical;GO:0012501//programmed cell death;GO:0006996//organelle organization;GO:0007154//cell communication;GO:0006950//response to stress;GO:0042221//response to chemical;GO:0012501//programmed cell death;GO:0006996//organelle organization;GO:0007154//cell communication;GO:0006950//response to stress;GO:0042221//response to chemical;GO:0012501//programmed cell death;GO:0006996//organelle organization;GO:0007154//cell communication;GO:0006950//response to stress;GO:0042221//response to chemical;GO:0012501//programmed cell death;GO:0006996//organelle organization;GO:0007154//cell communication gi|11225264|ref|NP_062264.1|/1.7385e-149/lymphocyte-specific protein 1 isoform 2 [Mus musculus] 320508 4981 0.73 0.806666667 0.144076178 Up 0.135864455 Cachd1 cache domain containing 1 K10798|1|1e-68|265|cin:100186084|poly [ADP-ribose] polymerase [EC:2.4.2.30];K04859|2|1e-25|122|phi:102113307|voltage-dependent calcium channel alpha-2/delta-2 GO:0031224//intrinsic component of membrane - GO:0070838//divalent metal ion transport gi|39930563|ref|NP_932154.1|/0/VWFA and cache domain-containing protein 1 precursor [Mus musculus] 30947 3159 0.766666667 0.846666667 0.143194636 Up 0.135864455 Adat1 "adenosine deaminase, tRNA-specific 1" K15440|1|0.0|1020|mmu:30947|tRNA-specific adenosine deaminase 1 [EC:3.5.4.34] - GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0004000//adenosine deaminase activity GO:0006399//tRNA metabolic process;GO:0010467//gene expression gi|7304859|ref|NP_038953.1|/0/tRNA-specific adenosine deaminase 1 [Mus musculus] 21844 6368.71 0.74 0.816666667 0.142222073 Up 0.135864455 Tiam1 T cell lymphoma invasion and metastasis 1 K05731|1|0.0|2956|mmu:21844|T-lymphoma invasion and metastasis-inducing protein 1 GO:0016020//membrane;GO:0030054//cell junction;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044464;GO:0030054//cell junction;GO:0016020//membrane;GO:0030054//cell junction;GO:0044444//cytoplasmic part GO:0004871//signal transducer activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005102//receptor binding;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005102//receptor binding;GO:0008289//lipid binding;GO:0004871//signal transducer activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005102//receptor binding;GO:0008289//lipid binding GO:0012501//programmed cell death;GO:0007409//axonogenesis;GO:0010975//regulation of neuron projection development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007409//axonogenesis;GO:0010975//regulation of neuron projection development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0012501//programmed cell death;GO:0007409//axonogenesis;GO:0010975//regulation of neuron projection development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|225543222|ref|NP_033410.2|/0/T-lymphoma invasion and metastasis-inducing protein 1 isoform 1 [Mus musculus] 66410 1486 11.37 11.09 -0.035972889 Down 0.135808041 Mterf3 mitochondrial transcription termination factor 3 "K15032|1|0.0|756|mmu:66410|mTERF domain-containing protein, mitochondrial" GO:0043231//intracellular membrane-bounded organelle GO:0000975//regulatory region DNA binding "GO:0006351//transcription, DNA-templated" "gi|171906591|ref|NP_079823.2|/0/transcription termination factor 3, mitochondrial precursor [Mus musculus]" 228361 5206.2 9.423333333 9.143333333 -0.043517261 Down 0.135808041 Ambra1 autophagy/beclin 1 regulator 1 K17985|1|0.0|2295|mmu:228361|activating molecule in BECN1-regulated autophagy protein 1 GO:0031982//vesicle - GO:0008283//cell proliferation;GO:0007399//nervous system development;GO:0044248;GO:0006915//apoptotic process;GO:0048869//cellular developmental process "gi|148695629|gb|EDL27576.1|/0/RIKEN cDNA D030051N19, isoform CRA_a [Mus musculus]" 79560 2155 11.12 11.40333333 0.036298815 Up 0.135808041 Ublcp1 ubiquitin-like domain containing CTD phosphatase 1 K17618|1|2e-165|585|mmu:79560|ubiquitin-like domain-containing CTD phosphatase 1 [EC:3.1.3.16] GO:0031981//nuclear lumen GO:0016791//phosphatase activity - gi|46575895|ref|NP_077795.2|/1.50882e-164/ubiquitin-like domain-containing CTD phosphatase 1 [Mus musculus] 26363 1956 9.636666667 9.916666667 0.04132106 Up 0.135808041 Btd biotinidase K01435|1|0.0|1092|mmu:26363|biotinidase [EC:3.5.1.12] GO:0043025//neuronal cell body;GO:0031981//nuclear lumen "GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0006790//sulfur compound metabolic process gi|13384648|ref|NP_079571.1|/0/biotinidase precursor [Mus musculus] 19248 3190 9.506666667 9.223333333 -0.043651338 Down 0.135808041 Ptpn12 "protein tyrosine phosphatase, non-receptor type 12" K18024|1|0.0|1433|mmu:19248|tyrosine-protein phosphatase non-receptor type 12/18/22 [EC:3.1.3.48] GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0015629//actin cytoskeleton GO:0004725//protein tyrosine phosphatase activity;GO:0019904//protein domain specific binding GO:0009888//tissue development;GO:0006470//protein dephosphorylation gi|34328195|ref|NP_035333.2|/0/tyrosine-protein phosphatase non-receptor type 12 [Mus musculus] 15248 3288.39 11.65666667 11.37333333 -0.035500149 Down 0.135808041 Hic1 hypermethylated in cancer 1 "K08583|1|6e-54|216|chx:102175325|calpain, small subunit 1;K09228|2|6e-28|129|gja:107122447|KRAB domain-containing zinc finger protein" GO:0031981//nuclear lumen;GO:0043232;GO:0031981//nuclear lumen;GO:0043232 GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0019899//enzyme binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0019899//enzyme binding GO:0006974//cellular response to DNA damage stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0035556//intracellular signal transduction;GO:0006974//cellular response to DNA damage stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0035556//intracellular signal transduction gi|148228529|ref|NP_001091673.1|/0/hypermethylated in cancer 1 protein isoform 2 [Mus musculus] 216001 2358 9.296666667 9.013333333 -0.044652783 Down 0.135808041 Micu1 mitochondrial calcium uptake 1 "K09518|1|6e-21|105|aam:106492651|DnaJ homolog subfamily B member 12;K20028|2|7e-11|72.0|oaa:100078401|palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225];K15105|3|9e-09|65.1|cmk:103176447|solute carrier family 25 (mitochondrial aspartate/glutamate transporter), member 12/13" GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031301//integral component of organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031301//integral component of organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031301//integral component of organelle membrane GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0070588//calcium ion transmembrane transport;GO:0006874//cellular calcium ion homeostasis;GO:0070588//calcium ion transmembrane transport;GO:0006874//cellular calcium ion homeostasis;GO:0070588//calcium ion transmembrane transport;GO:0006874//cellular calcium ion homeostasis "gi|148700251|gb|EDL32198.1|/0/calcium binding atopy-related autoantigen 1, isoform CRA_b, partial [Mus musculus]" 15257 7926.36 10.75333333 11.03666667 0.037520572 Up 0.135808041 Hipk1 homeodomain interacting protein kinase 1 K08826|1|0.0|1982|mmu:15257|homeodomain interacting protein kinase [EC:2.7.11.1] GO:0016604//nuclear body;GO:0016604//nuclear body GO:0032550;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0004672//protein kinase activity;GO:0003676//nucleic acid binding;GO:0032550;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0004672//protein kinase activity;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0051099//positive regulation of binding;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0008283//cell proliferation;GO:0006796//phosphate-containing compound metabolic process;GO:0003002//regionalization;GO:0031076//embryonic camera-type eye development;GO:0030154//cell differentiation;GO:0006464//cellular protein modification process;GO:0003407//neural retina development;GO:0048598//embryonic morphogenesis;GO:0002089//lens morphogenesis in camera-type eye;GO:0030097//hemopoiesis;GO:0001525//angiogenesis;GO:0006351//transcription, DNA-templated;GO:0051099//positive regulation of binding;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0008283//cell proliferation;GO:0006796//phosphate-containing compound metabolic process;GO:0003002//regionalization;GO:0031076//embryonic camera-type eye development;GO:0030154//cell differentiation;GO:0006464//cellular protein modification process;GO:0003407//neural retina development;GO:0048598//embryonic morphogenesis;GO:0002089//lens morphogenesis in camera-type eye" gi|5305333|gb|AAD41593.1|AF071071_1/0/protein kinase Myak-S [Mus musculus] 104418 3762.87 31.15666667 31.81666667 0.030241804 Up 0.135610591 Dgkz diacylglycerol kinase zeta K00901|1|0.0|1745|mmu:104418|diacylglycerol kinase (ATP) [EC:2.7.1.107] GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0031252//cell leading edge;GO:0043231//intracellular membrane-bounded organelle;GO:0031252//cell leading edge;GO:0016020//membrane GO:0016301//kinase activity;GO:0032550;GO:0005515//protein binding;GO:0043169//cation binding;GO:0030234//enzyme regulator activity;GO:0043169//cation binding;GO:0032550;GO:0030234//enzyme regulator activity;GO:0005515//protein binding;GO:0016301//kinase activity GO:0000278//mitotic cell cycle;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007265//Ras protein signal transduction;GO:0007599//hemostasis;GO:0016310//phosphorylation;GO:0044773//mitotic DNA damage checkpoint;GO:0048870//cell motility;GO:0044092//negative regulation of molecular function;GO:0001775//cell activation;GO:0000278//mitotic cell cycle;GO:0007265//Ras protein signal transduction;GO:0044092//negative regulation of molecular function;GO:0044773//mitotic DNA damage checkpoint;GO:0016310//phosphorylation;GO:0007186//G-protein coupled receptor signaling pathway gi|262205333|ref|NP_001160069.1|/0/diacylglycerol kinase zeta isoform 1 [Mus musculus] 12946 1674 28.15333333 28.81666667 0.033597717 Up 0.135610591 Cr1l complement component (3b/4b) receptor 1-like K04005|1|0.0|778|mmu:12946|complement receptor related protein;K04011|4|4e-101|371|hsa:1378|complement component (3b/4b) receptor 1 GO:0031224//intrinsic component of membrane;GO:0009986//cell surface - GO:0002698;GO:0044703;GO:0006091//generation of precursor metabolites and energy;GO:0044699;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0002673//regulation of acute inflammatory response;GO:0032501//multicellular organismal process;GO:0032502//developmental process gi|52426750|ref|NP_038527.2|/0/complement component receptor 1-like protein [Mus musculus] 12995 4208 32.62666667 33.28333333 0.028748326 Up 0.135610591 Csnk2a1 "casein kinase 2, alpha 1 polypeptide" K03097|1|0.0|738|mmu:12995|casein kinase II subunit alpha [EC:2.7.11.1] GO:0016020//membrane;GO:0070822//Sin3-type complex;GO:0044444//cytoplasmic part GO:0032550;GO:0004672//protein kinase activity;GO:0031072//heat shock protein binding;GO:0019208//phosphatase regulator activity "GO:0006351//transcription, DNA-templated;GO:0006457//protein folding;GO:0016055//Wnt signaling pathway;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0006468//protein phosphorylation;GO:0006935//chemotaxis;GO:0016049//cell growth;GO:0009896;GO:0007093//mitotic cell cycle checkpoint" gi|1262300|gb|AAA96795.1|/0/casein kinase II alpha subunit [Mus musculus] 214685 2547 0.54 0.613333333 0.183711953 Up 0.135572981 Chadl chondroadherin-like K06248|1|7e-57|224|myd:102768490|chondroadherin - - - - 15410 3313 0.496666667 0.563333333 0.181710916 Up 0.135572981 Hoxb3 homeobox B3 K09303|1|0.0|689|mmu:15410|homeobox protein HoxA/B/D3 - GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding "GO:0035270//endocrine system development;GO:0003002//regionalization;GO:0022008//neurogenesis;GO:0030097//hemopoiesis;GO:0021563//glossopharyngeal nerve development;GO:0001501//skeletal system development;GO:0048562//embryonic organ morphogenesis;GO:0030902//hindbrain development;GO:0006351//transcription, DNA-templated;GO:0035270//endocrine system development;GO:0003002//regionalization;GO:0022008//neurogenesis;GO:0030097//hemopoiesis;GO:0021563//glossopharyngeal nerve development;GO:0001501//skeletal system development;GO:0048562//embryonic organ morphogenesis;GO:0030902//hindbrain development;GO:0006351//transcription, DNA-templated" gi|120300900|ref|NP_001073338.1|/0/homeobox protein Hox-B3 [Mus musculus] 18227 3172 0.593333333 0.523333333 -0.181112682 Down 0.135572981 Nr4a2 "nuclear receptor subfamily 4, group A, member 2" K08558|1|0.0|1090|pale:102878015|nuclear receptor subfamily 4 group A member 2 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003677//DNA binding" GO:0007585//respiratory gaseous exchange;GO:0014075//response to amine;GO:0048469//cell maturation;GO:0007626//locomotory behavior;GO:0006366//transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0009755//hormone-mediated signaling pathway;GO:0009636//response to toxic substance;GO:0042069//regulation of catecholamine metabolic process;GO:0042417//dopamine metabolic process;GO:0044093;GO:0006950//response to stress;GO:0021538//epithalamus development;GO:0016477//cell migration;GO:0021955//central nervous system neuron axonogenesis;GO:0007585//respiratory gaseous exchange;GO:0014075//response to amine;GO:0048469//cell maturation;GO:0007626//locomotory behavior;GO:0006366//transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0009755//hormone-mediated signaling pathway;GO:0009636//response to toxic substance;GO:0042069//regulation of catecholamine metabolic process;GO:0042417//dopamine metabolic process;GO:0044093;GO:0006950//response to stress;GO:0021538//epithalamus development;GO:0016477//cell migration;GO:0021955//central nervous system neuron axonogenesis gi|530370485|ref|XP_005246678.1|/0/PREDICTED: nuclear receptor subfamily 4 group A member 2 isoform X1 [Homo sapiens] 545260 1722 0.54 0.61 0.175849835 Up 0.135572981 Arsi arylsulfatase i K12375|1|0.0|1119|mmu:545260|arylsulfatase I/J [EC:3.1.6.-] GO:0044432 GO:0008484//sulfuric ester hydrolase activity;GO:0043169//cation binding GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006664//glycolipid metabolic process gi|84370328|ref|NP_001033588.1|/0/arylsulfatase I precursor [Mus musculus] 69522 508 0.616666667 0.543333333 -0.182653306 Down 0.135572981 2310002D06Rik RIKEN cDNA 2310002D06 gene - - - - - 67620 3420 0.526666667 0.596666667 0.180035029 Up 0.135572981 Lrp2bp Lrp2 binding protein K14026|1|3e-12|77.0|cfo:105251818|SEL1 protein - - - "gi|148703618|gb|EDL35565.1|/0/Lrp2 binding protein, isoform CRA_b [Mus musculus]" 98303 2192.54 0.39 0.333333333 -0.22650853 Down 0.135554177 D630023F18Rik RIKEN cDNA D630023F18 gene - - - - gi|30424962|ref|NP_780502.1|/1.42284e-117/uncharacterized protein C2orf80 homolog isoform 1 [Mus musculus] 22218 1230 29.21333333 28.56 -0.032631004 Down 0.135516567 Sumo1 small ubiquitin-like modifier 1 K12160|1|3e-65|239|ecb:100067107|small ubiquitin-related modifier GO:0043005//neuron projection;GO:0016604//nuclear body;GO:0005635//nuclear envelope GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity "GO:0006351//transcription, DNA-templated;GO:0006461//protein complex assembly;GO:0034504//protein localization to nucleus;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0051100//negative regulation of binding;GO:0006259//DNA metabolic process;GO:0048856//anatomical structure development;GO:0031331;GO:0032446//protein modification by small protein conjugation;GO:0030575//nuclear body organization" gi|594115840|ref|XP_006080600.1|/2.39131e-65/PREDICTED: uncharacterized protein LOC102390768 [Bubalus bubalis] 27362 1865 31.32333333 30.67 -0.030409581 Down 0.135516567 Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 K09515|1|1e-116|423|mmu:27362|DnaJ homolog subfamily B member 9 - - - - 19167 2374 28.54666667 27.89333333 -0.033401944 Down 0.135516567 Psma3 "proteasome (prosome, macropain) subunit, alpha type 3" K02727|1|1e-131|408|ocu:100338517|20S proteasome subunit alpha 7 [EC:3.4.25.1] - - - - 22402 5022 0.233333333 0.183333333 -0.347923303 Down 0.135497762 Wisp1 WNT1 inducible signaling pathway protein 1 K06827|1|2e-87|327|lcm:102363650|connective tissue growth factor GO:0044421;GO:0044424 GO:0019838//growth factor binding GO:0007166//cell surface receptor signaling pathway;GO:0016049//cell growth;GO:0022610 "gi|148697435|gb|EDL29382.1|/0/WNT1 inducible signaling pathway protein 1, isoform CRA_d, partial [Mus musculus]" 245884 1203 0.246666667 0.193333333 -0.351472371 Down 0.135497762 Fam71f2 "family with sequence similarity 71, member F2" - - - - gi|162138899|ref|NP_001094956.1|/1.35764e-144/protein FAM71F2 [Mus musculus] 20211 2067 0.23 0.18 -0.353636955 Down 0.135497762 Saa4 serum amyloid A 4 K17310|1|6e-73|278|mmu:20211|serum amyloid A protein GO:0034358//plasma lipoprotein particle - GO:0002526//acute inflammatory response gi|6755398|ref|NP_035446.1|/4.92066e-72/serum amyloid A-4 protein precursor [Mus musculus] 98258 4596 9.1 8.83 -0.043453107 Down 0.135309715 Txndc9 thioredoxin domain containing 9 - GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle - GO:0019725//cellular homeostasis "gi|148704684|gb|EDL36631.1|/1.3845e-123/mCG7607, partial [Mus musculus]" 50492 2585 9.586666667 9.313333333 -0.041731655 Down 0.135309715 Thop1 thimet oligopeptidase 1 K01392|1|0.0|1353|mmu:50492|thimet oligopeptidase [EC:3.4.24.15] GO:0044424 GO:0033218//amide binding;GO:0004175//endopeptidase activity;GO:0043169//cation binding GO:0035556//intracellular signal transduction;GO:0019538//protein metabolic process;GO:0043603//cellular amide metabolic process gi|239916005|ref|NP_073144.3|/0/thimet oligopeptidase [Mus musculus] 14773 3182 9.916666667 10.18333333 0.038282712 Up 0.135309715 Grk5 G protein-coupled receptor kinase 5 K08291|1|0.0|1091|mmu:14773|G protein-coupled receptor kinase [EC:2.7.11.16] - - - - 102607 5541 9.886666667 10.16 0.039344305 Up 0.135309715 Snx19 sorting nexin 19 K17930|1|0.0|1739|mmu:102607|sorting nexin-19 - - - - 14594 3562.39 9.096666667 9.363333333 0.04168423 Up 0.135309715 Ggta1 "glycoprotein galactosyltransferase alpha 1, 3" K00743|1|0.0|817|mmu:14594|N-acetyllactosaminide 3-alpha-galactosyltransferase [EC:2.4.1.87] GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0035250//UDP-galactosyltransferase activity;GO:0043169//cation binding;GO:0035250//UDP-galactosyltransferase activity;GO:0043169//cation binding;GO:0035250//UDP-galactosyltransferase activity;GO:0043169//cation binding;GO:0035250//UDP-galactosyltransferase activity GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process "gi|224922808|ref|NP_034413.2|/0/N-acetyllactosaminide alpha-1,3-galactosyltransferase isoform 1 [Mus musculus]" 72183 1879 8.916666667 9.183333333 0.042513427 Up 0.135309715 Snx6 sorting nexin 6 K17920|1|0.0|775|rro:104664905|sorting nexin-5/6/32 GO:0012506//vesicle membrane;GO:0005769//early endosome GO:0005543//phospholipid binding;GO:0042802//identical protein binding "GO:0006351//transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0007176//regulation of epidermal growth factor-activated receptor activity" gi|724798402|ref|XP_010364893.1|/0/PREDICTED: sorting nexin-6 isoform X1 [Rhinopithecus roxellana] 59044 1952.3 27.08 27.70666667 0.033005415 Up 0.135262703 Rnf130 ring finger protein 130 K15701|1|0.0|713|rno:652955|E3 ubiquitin-protein ligase RNF130 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0012501//programmed cell death;GO:0012501//programmed cell death;GO:0012501//programmed cell death gi|83320103|ref|NP_001032747.1|/0/E3 ubiquitin-protein ligase RNF130 precursor [Rattus norvegicus] 14430 2118.25 26.68 27.29666667 0.032966121 Up 0.135149874 Galt galactose-1-phosphate uridyl transferase K00965|1|0.0|743|rno:298003|UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0048029//monosaccharide binding;GO:0046914//transition metal ion binding;GO:0070569//uridylyltransferase activity;GO:0048029//monosaccharide binding;GO:0046914//transition metal ion binding;GO:0070569//uridylyltransferase activity GO:0006011//UDP-glucose metabolic process;GO:0019318//hexose metabolic process;GO:0006011//UDP-glucose metabolic process;GO:0019318//hexose metabolic process gi|918628264|ref|XP_013378474.1|/1.99418e-112/PREDICTED: galactose-1-phosphate uridylyltransferase isoform X2 [Chinchilla lanigera] 75799 1844 0.19 0.24 0.337034987 Up 0.135112264 4930444P10Rik RIKEN cDNA 4930444P10 gene - - - - gi|568905505|ref|XP_006495645.1|/7.01846e-75/PREDICTED: putative uncharacterized protein C8orf89 homolog isoform X2 [Mus musculus] 268297 4745 0.2 0.253333333 0.341036918 Up 0.135112264 Scml4 sex comb on midleg-like 4 (Drosophila) K11466|1|0.0|773|mmu:268297|sex comb on midleg-like protein 4 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|568965433|ref|XP_006512813.1|/0/PREDICTED: sex comb on midleg-like protein 4 isoform X1 [Mus musculus] 67801 1889 0.256666667 0.203333333 -0.336049203 Down 0.135112264 Pllp plasma membrane proteolipid - GO:0031224//intrinsic component of membrane;GO:0043209//myelin sheath - GO:0044765//single-organism transport;GO:0008366//axon ensheathment;GO:0006950//response to stress gi|20279132|ref|NP_080661.1|/7.47939e-80/plasmolipin [Mus musculus] 67466 2859 5.146666667 5.34 0.053201395 Up 0.135084057 Pdcl phosducin-like K08327|1|4e-53|212|lcm:102351161|phosducin - GO:0005515//protein binding GO:0050953//sensory perception of light stimulus;GO:0042026//protein refolding "gi|148676757|gb|EDL08704.1|/6.42719e-137/phosducin-like, isoform CRA_a, partial [Mus musculus]" 67285 1884 5.68 5.866666667 0.046650093 Up 0.135084057 Cwc27 CWC27 spliceosome-associated protein K12737|1|0.0|783|mmu:67285|peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8] - - - - 15931 4988 5.64 5.45 -0.049438933 Down 0.135084057 Ids iduronate 2-sulfatase K01136|1|0.0|1139|mmu:15931|iduronate 2-sulfatase [EC:3.1.6.13] GO:0000323//lytic vacuole GO:0008484//sulfuric ester hydrolase activity;GO:0043169//cation binding - gi|84781812|ref|NP_034628.2|/0/iduronate 2-sulfatase precursor [Mus musculus] 98496 2667 4.916666667 5.103333333 0.053759328 Up 0.135084057 Pid1 phosphotyrosine interaction domain containing 1 - GO:0043231//intracellular membrane-bounded organelle - GO:0070741//response to interleukin-6;GO:0008284//positive regulation of cell proliferation;GO:0042391//regulation of membrane potential;GO:0051129;GO:0006754//ATP biosynthetic process;GO:0072593//reactive oxygen species metabolic process;GO:1901990//regulation of mitotic cell cycle phase transition;GO:0006366//transcription from RNA polymerase II promoter;GO:0046325//negative regulation of glucose import;GO:0070542//response to fatty acid;GO:0034612//response to tumor necrosis factor;GO:0008286//insulin receptor signaling pathway;GO:0090296//regulation of mitochondrial DNA replication gi|74191343|dbj|BAE30254.1|/1.76897e-165/unnamed protein product [Mus musculus] 217827 3710 5.403333333 5.213333333 -0.051643578 Down 0.135084057 Nrde2 "nrde-2 necessary for RNA interference, domain containing" - - - - gi|594140517|ref|NP_001277232.1|/0/protein NRDE2 homolog isoform a [Mus musculus] 140500 4438 5.273333333 5.086666667 -0.051994638 Down 0.135084057 Acap3 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 3" "K12489|1|0.0|1333|mmu:140500|Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein" - - - "gi|46402197|ref|NP_997106.1|/0/arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 [Mus musculus]" 67865 875 5.603333333 5.796666667 0.048938208 Up 0.135084057 Rgs10 regulator of G-protein signalling 10 K16449|1|5e-83|309|mmu:67865|regulator of G-protein signaling - - - - 66869 3237.42 5.79 5.976666667 0.045777734 Up 0.135084057 Zfp869 zinc finger protein 869 K09228|1|0.0|1083|mmu:66869|KRAB domain-containing zinc finger protein - - - "gi|148696799|gb|EDL28746.1|/0/mCG23322, isoform CRA_a, partial [Mus musculus]" 71998 1827 5.816666667 5.623333333 -0.048767063 Down 0.135084057 Slc25a35 "solute carrier family 25, member 35" "K15117|1|7e-162|573|mmu:71998|solute carrier family 25, member 34/35" GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0051234//establishment of localization gi|21312550|ref|NP_082324.1|/6.32116e-161/solute carrier family 25 member 35 [Mus musculus] 66262 4539 2.703333333 2.576666667 -0.0692335 Down 0.135008838 Ing5 "inhibitor of growth family, member 5" K11345|1|4e-120|436|mmu:66262|inhibitor of growth protein 5 GO:0070775 GO:0046914//transition metal ion binding;GO:0042393//histone binding "GO:0006351//transcription, DNA-templated;GO:0040007//growth;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0006259//DNA metabolic process;GO:0000084//mitotic S phase;GO:0016573//histone acetylation" gi|21313552|ref|NP_079730.1|/3.47766e-119/inhibitor of growth protein 5 [Mus musculus] 70568 5646 2.756666667 2.623333333 -0.071523694 Down 0.135008838 Cpne3 copine III K19906|1|6e-12|77.0|sko:100376714|synaptotagmin-6;K06491|2|1e-10|72.8|cin:100183448|neural cell adhesion molecule;K19902|3|1e-09|69.3|pss:102458891|synaptotagmin-2;K11348|4|1e-09|69.3|apla:101800649|bromodomain and PHD finger-containing protein 1;K15290|5|4e-09|67.8|amj:102562511|synaptotagmin-1 GO:0044444//cytoplasmic part - GO:0006464//cellular protein modification process gi|60360050|dbj|BAD90244.1|/0/mKIAA0636 protein [Mus musculus] 100616095 1500 2.73 2.856666667 0.065431752 Up 0.135008838 Snhg18 small nucleolar RNA host gene 18 - - - - gi|148676924|gb|EDL08871.1|/1.63584e-15/mCG147260 [Mus musculus] 268980 3965 2.706666667 2.833333333 0.065983114 Up 0.135008838 Strn "striatin, calmodulin binding protein" K17608|1|0.0|1351|mmu:268980|striatin 1/3/4 - - - gi|2828301|emb|CAA11545.1|/0/striatin [Mus musculus] 326622 5174 2.4 2.526666667 0.074200942 Up 0.135008838 Upf2 UPF2 regulator of nonsense transcripts homolog (yeast) K14327|1|0.0|2049|mmu:326622|regulator of nonsense transcripts 2 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - GO:0009887//organ morphogenesis;GO:0035966//response to topologically incorrect protein gi|124487283|ref|NP_001074601.1|/0/regulator of nonsense transcripts 2 [Mus musculus] 52615 4449 2.886666667 2.756666667 -0.066479696 Down 0.135008838 Suz12 suppressor of zeste 12 homolog (Drosophila) K11463|1|0.0|1367|mmu:52615|polycomb protein SUZ12 GO:0031519//PcG protein complex;GO:0000803//sex chromosome;GO:0031519//PcG protein complex;GO:0000803//sex chromosome GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0008276//protein methyltransferase activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0008276//protein methyltransferase activity;GO:0003677//DNA binding "GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0016567//protein ubiquitination;GO:0030154//cell differentiation;GO:0006479//protein methylation;GO:0006325//chromatin organization;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0016567//protein ubiquitination;GO:0030154//cell differentiation;GO:0006479//protein methylation;GO:0006325//chromatin organization" "gi|148683670|gb|EDL15617.1|/0/suppressor of zeste 12 homolog (Drosophila), isoform CRA_c, partial [Mus musculus]" 12488 5427 2.576666667 2.706666667 0.071011313 Up 0.135008838 Cd2ap CD2-associated protein K13738|1|0.0|932|mmu:12488|CD2-associated protein "GO:0031981//nuclear lumen;GO:0031252//cell leading edge;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005884//actin filament;GO:0016020//membrane" GO:0005126//cytokine receptor binding;GO:0050839//cell adhesion molecule binding;GO:0019904//protein domain specific binding GO:0006996//organelle organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0048870//cell motility;GO:0007155//cell adhesion;GO:0006898//receptor-mediated endocytosis gi|125987599|ref|NP_033977.3|/0/CD2-associated protein [Mus musculus] 214855 5696.34 2.566666667 2.7 0.073063462 Up 0.135008838 Arid5a AT rich interactive domain 5A (MRF1-like) - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter "gi|148682529|gb|EDL14476.1|/0/AT rich interactive domain 5A (Mrf1 like), isoform CRA_a, partial [Mus musculus]" 232449 1688 2.63 2.763333333 0.071346801 Up 0.135008838 Dera deoxyribose-phosphate aldolase (putative) K01619|1|7e-180|632|mmu:232449|deoxyribose-phosphate aldolase [EC:4.1.2.4] - - - - 72993 6961 2.6 2.726666667 0.068626719 Up 0.135008838 Appl1 "adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1" K08733|1|0.0|1288|mmu:72993|DCC-interacting protein 13 alpha GO:0000118//histone deacetylase complex;GO:0005769//early endosome;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0008289//lipid binding;GO:0019901//protein kinase binding GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0051128//regulation of cellular component organization;GO:0010827//regulation of glucose transport gi|21699066|ref|NP_660256.1|/0/DCC-interacting protein 13-alpha [Mus musculus] 16348 5668.42 2.47 2.596666667 0.072149786 Up 0.135008838 Invs inversin K19626|1|0.0|1835|rno:313228|inversin GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0005856//cytoskeleton GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0030178//negative regulation of Wnt signaling pathway;GO:0035050//embryonic heart tube development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0035050//embryonic heart tube development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0035050//embryonic heart tube development gi|568926105|ref|XP_006537695.1|/0/PREDICTED: inversin isoform X7 [Mus musculus] 71336 1047 2.593333333 2.723333333 0.070565923 Up 0.135008838 Rbks ribokinase K00852|1|1e-160|567|mmu:71336|ribokinase [EC:2.7.1.15] - "GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032550" GO:0019321;GO:0006796//phosphate-containing compound metabolic process gi|23397419|ref|NP_694876.1|/1.20552e-159/ribokinase [Mus musculus] 11564 3712 25.24333333 25.85 0.034261853 Up 0.134999436 Adsl adenylosuccinate lyase K01756|1|0.0|969|mmu:11564|adenylosuccinate lyase [EC:4.3.2.2] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0016842 GO:0051259//protein oligomerization;GO:0006188//IMP biosynthetic process;GO:0031667//response to nutrient levels;GO:0045333//cellular respiration;GO:0014823//response to activity;GO:0006167//AMP biosynthetic process;GO:0009112;GO:0006950//response to stress gi|29788764|ref|NP_033764.2|/0/adenylosuccinate lyase [Mus musculus] 102466888 127 3.733333333 3.88 0.055592326 Up 0.134980631 Mir8099-2 microRNA 8099-2 - - - - - 170716 1731 3.903333333 4.056666667 0.055588092 Up 0.134980631 Cyp4f13 "cytochrome P450, family 4, subfamily f, polypeptide 13" "K17726|1|0.0|1060|mmu:170716|leukotriene-B4 20-monooxygenase / phylloquinone omega-hydroxylase [EC:1.14.13.30 1.14.13.194];K00490|5|0.0|895|cge:100754807|cytochrome P450, family 4, subfamily F [EC:1.14.14.1]" GO:0031090//organelle membrane "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0006952//defense response;GO:0006690//icosanoid metabolic process "gi|20373155|ref|NP_570952.1|/0/cytochrome P450, family 4, subfamily f, polypeptide 13 [Mus musculus]" 56291 4258 3.556666667 3.706666667 0.059596612 Up 0.134980631 Styx serine/threonine/tyrosine interaction protein K18042|1|3e-125|452|mmu:56291|serine/threonine/tyrosine-interacting protein GO:0044424 - GO:0048232//male gamete generation gi|46852143|ref|NP_062611.2|/2.56772e-124/serine/threonine/tyrosine-interacting protein [Mus musculus] 16854 1406 3.363333333 3.516666667 0.064316824 Up 0.134980631 Lgals3 "lectin, galactose binding, soluble 3" K06831|1|5e-81|265|rno:83781|galectin-3 GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031012//extracellular matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031012//extracellular matrix GO:0005515//protein binding;GO:0005515//protein binding GO:0043062//extracellular structure organization;GO:0048731//system development;GO:0006396//RNA processing;GO:0043062//extracellular structure organization;GO:0048731//system development;GO:0006396//RNA processing gi|559812781|gb|AHB20285.1|/1.37432e-81/lectin galactoside-binding soluble 3 protein [Rattus norvegicus] 22317 3129.27 3.873333333 3.723333333 -0.056980883 Down 0.134980631 Vamp1 vesicle-associated membrane protein 1 K08510|1|3e-39|166|tup:102480035|vesicle-associated membrane protein 1 GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane;GO:0008021//synaptic vesicle;GO:0030139//endocytic vesicle;GO:0042995//cell projection;GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane;GO:0008021//synaptic vesicle;GO:0030139//endocytic vesicle;GO:0042995//cell projection GO:0005488//binding;GO:0005488//binding GO:0006810//transport;GO:0001505//regulation of neurotransmitter levels;GO:0006810//transport;GO:0001505//regulation of neurotransmitter levels gi|74186948|dbj|BAE20518.1|/4.64965e-68/unnamed protein product [Mus musculus] 102465890 127 3.733333333 3.88 0.055592326 Up 0.134980631 Mir8099-1 microRNA 8099-1 - - - - - 665378 1621 3.35 3.503333333 0.064567168 Up 0.134980631 Gm7609 predicted pseudogene 7609 K15413|1|6e-24|114|mmu:20684|nuclear autoantigen Sp-100 - - - gi|568907745|ref|XP_006496584.1|/3.75013e-162/PREDICTED: component of Sp100-rs-like isoform X2 [Mus musculus] 109333 6207 3.873333333 3.72 -0.058273042 Down 0.134980631 Pkn2 protein kinase N2 K06071|1|0.0|1677|mmu:109333|protein kinase N [EC:2.7.11.13] - - - - 217109 2613 3.596666667 3.75 0.060230137 Up 0.134980631 Utp18 UTP18 small subunit processome component K14553|1|0.0|965|mmu:217109|U3 small nucleolar RNA-associated protein 18 GO:0043231//intracellular membrane-bounded organelle - GO:0042254//ribosome biogenesis gi|61656180|ref|NP_001013393.1|/0/U3 small nucleolar RNA-associated protein 18 homolog [Mus musculus] 72179 3203 0.403333333 0.346666667 -0.218423519 Down 0.13489601 Fbxl2 F-box and leucine-rich repeat protein 2 K10268|1|0.0|866|mmu:72179|F-box and leucine-rich repeat protein 2/20 GO:0044424 GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity GO:0019941//modification-dependent protein catabolic process;GO:0016567//protein ubiquitination gi|30519963|ref|NP_848739.1|/0/F-box/LRR-repeat protein 2 [Mus musculus] 243300 3517 0.426666667 0.366666667 -0.218640286 Down 0.13489601 Nyap1 neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1 K17481|1|3e-21|107|amj:102566129|myosin XVI GO:0044464 - GO:0031175//neuron projection development;GO:0048015//phosphatidylinositol-mediated signaling "gi|148687294|gb|EDL19241.1|/0/RIKEN cDNA 6430598A04, isoform CRA_a, partial [Mus musculus]" 12481 1144 0.393333333 0.456666667 0.215389034 Up 0.13489601 Cd2 CD2 antigen K06449|1|2e-159|563|mmu:12481|CD2 antigen GO:0009986//cell surface;GO:0044459;GO:0031225//anchored component of membrane;GO:0032991//macromolecular complex GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0019900//kinase binding GO:0046649//lymphocyte activation;GO:0007155//cell adhesion gi|7304949|ref|NP_038514.1|/1.99735e-158/T-cell surface antigen CD2 precursor [Mus musculus] 71690 2163 0.416666667 0.356666667 -0.224317298 Down 0.13489601 Esm1 endothelial cell-specific molecule 1 K08785|1|4e-07|59.3|acs:100560592|HtrA serine peptidase 3 [EC:3.4.21.-];K08784|2|1e-06|58.2|xma:102219577|HtrA serine peptidase 1 [EC:3.4.21.-];K08786|3|1e-06|57.8|bta:514946|HtrA serine peptidase 4 [EC:3.4.21.-] - - - - 414124 1296 0.21 0.263333333 0.326500825 Up 0.134773779 F730035M05Rik RIKEN cDNA F730035M05 gene - GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0046872//metal ion binding GO:0032446//protein modification by small protein conjugation "gi|148704738|gb|EDL36685.1|/4.01533e-12/survivor of motor neuron protein interacting protein 1, isoform CRA_a, partial [Mus musculus]" 235533 2746 0.203333333 0.253333333 0.317190176 Up 0.134773779 Gk5 glycerol kinase 5 (putative) K19583|1|0.0|986|mmu:235533|putative glycerol kinase 5 [EC:2.7.1.30] - GO:0016301//kinase activity;GO:0032550 GO:0019400;GO:0006796//phosphate-containing compound metabolic process "gi|148689003|gb|EDL20950.1|/0/RIKEN cDNA C330018K18, isoform CRA_c, partial [Mus musculus]" 244723 1525 0.26 0.206666667 -0.331205908 Down 0.134773779 Olfm2 olfactomedin 2 K04594|1|3e-52|208|amj:102563130|latrophilin 3 GO:0008328//ionotropic glutamate receptor complex - - gi|148747133|ref|NP_776138.2|/0/noelin-2 precursor [Mus musculus] 22712 2536 0.183333333 0.23 0.327164743 Up 0.134773779 Zfp54 zinc finger protein 54 K09228|1|0.0|1260|mmu:22712|KRAB domain-containing zinc finger protein GO:0005622//intracellular GO:0043169//cation binding - gi|40796097|gb|AAR91691.1|/0/zinc finger protein 54 [Mus musculus] 240913 3673 0.213333333 0.266666667 0.321928095 Up 0.134773779 Adamts4 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4" K07764|1|0.0|1652|mmu:240913|a disintegrin and metalloproteinase with thrombospondin motifs 4 [EC:3.4.24.82] GO:0044421;GO:0031012//extracellular matrix GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|27370274|ref|NP_766433.1|/0/A disintegrin and metalloproteinase with thrombospondin motifs 4 [Mus musculus] 223918 2454 10.13 10.39333333 0.037024253 Up 0.13469856 Spryd3 SPRY domain containing 3 K08844|1|2e-07|60.5|crg:105342840|leucine-rich repeat kinase 2 [EC:2.7.11.1] - - - gi|635065538|ref|XP_008001558.1|/0/PREDICTED: SPRY domain-containing protein 3 [Chlorocebus sabaeus] 54160 4016 9.746666667 10.00666667 0.037980666 Up 0.13469856 Copg2 "coatomer protein complex, subunit gamma 2" K17267|1|0.0|1650|mmu:54160|coatomer subunit gamma - - - - 67618 2870 8.466666667 8.21 -0.044411869 Down 0.13469856 Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase K06133|1|5e-110|219|chx:102190336|4'-phosphopantetheinyl transferase [EC:2.7.8.-] GO:0044444//cytoplasmic part "GO:0046872//metal ion binding;GO:0016780//phosphotransferase activity, for other substituted phosphate groups" GO:0006766//vitamin metabolic process;GO:0006575//cellular modified amino acid metabolic process;GO:0006631//fatty acid metabolic process;GO:0043170 gi|227496837|ref|NP_080552.3|/9.52899e-173/L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase [Mus musculus] 30938 3110 0.6 0.533333333 -0.169925001 Down 0.134679755 Fgd3 "FYVE, RhoGEF and PH domain containing 3" "K05722|1|0.0|1382|mmu:30938|FYVE, RhoGEF and PH domain containing 3" GO:0043232 GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0043169//cation binding;GO:0008289//lipid binding GO:0007266//Rho protein signal transduction;GO:0030031//cell projection assembly "gi|85719309|ref|NP_056574.2|/0/FYVE, RhoGEF and PH domain-containing protein 3 [Mus musculus]" 93960 4314 0.523333333 0.59 0.172984801 Up 0.134679755 Nkd1 naked cuticle 1 homolog (Drosophila) K03213|1|0.0|745|mmu:93960|naked cuticle GO:0016020//membrane;GO:0008287//protein serine/threonine phosphatase complex;GO:0044424;GO:0044424;GO:0016020//membrane GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0043169//cation binding;GO:0019904//protein domain specific binding GO:0051093//negative regulation of developmental process;GO:0030178//negative regulation of Wnt signaling pathway;GO:1901229;GO:0014807//regulation of somitogenesis;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:2000052//positive regulation of non-canonical Wnt signaling pathway;GO:0061061//muscle structure development;GO:0009896;GO:1901229;GO:2000052//positive regulation of non-canonical Wnt signaling pathway;GO:0048869//cellular developmental process;GO:0009896;GO:0030178//negative regulation of Wnt signaling pathway;GO:0051093//negative regulation of developmental process;GO:0048232//male gamete generation "gi|148679110|gb|EDL11057.1|/0/naked cuticle 1 homolog (Drosophila), partial [Mus musculus]" 171281 2594 0.646666667 0.576666667 -0.165284615 Down 0.134679755 Acot3 acyl-CoA thioesterase 3 K01068|1|0.0|785|mmu:171281|acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2] GO:0042579//microbody GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity GO:0006732;GO:0006631//fatty acid metabolic process gi|19527406|ref|NP_599007.1|/0/acyl-coenzyme A thioesterase 3 [Mus musculus] 233058 3334 0.676666667 0.603333333 -0.16549003 Down 0.134679755 Zfp420 zinc finger protein 420 K09228|1|0.0|1252|mmu:233058|KRAB domain-containing zinc finger protein - - - gi|254911025|ref|NP_766328.2|/0/zinc finger protein 420 [Mus musculus] 244650 7854 0.55 0.62 0.172836597 Up 0.134679755 Phlpp2 PH domain and leucine rich repeat protein phosphatase 2 K16340|1|0.0|2362|mmu:244650|PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16] GO:0001750//photoreceptor outer segment GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity GO:0006464//cellular protein modification process gi|295054247|ref|NP_001116066.2|/0/PH domain leucine-rich repeat-containing protein phosphatase 2 [Mus musculus] 110147 3956.01 25.14666667 24.56 -0.034056615 Down 0.13466095 Ehmt2 euchromatic histone lysine N-methyltransferase 2 K11420|1|0.0|2085|mmu:110147|euchromatic histone-lysine N-methyltransferase [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0018024//histone-lysine N-methyltransferase activity GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0032776//DNA methylation on cytosine;GO:0018022//peptidyl-lysine methylation;GO:0007128//meiotic prophase I;GO:0007281//germ cell development;GO:0007129//synapsis;GO:0034968//histone lysine methylation;GO:0006260//DNA replication;GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0032776//DNA methylation on cytosine;GO:0018022//peptidyl-lysine methylation;GO:0007128//meiotic prophase I;GO:0007281//germ cell development;GO:0007129//synapsis;GO:0034968//histone lysine methylation;GO:0006260//DNA replication;GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0032776//DNA methylation on cytosine;GO:0018022//peptidyl-lysine methylation;GO:0007128//meiotic prophase I;GO:0007281//germ cell development;GO:0007129//synapsis;GO:0034968//histone lysine methylation;GO:0006260//DNA replication;GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0032776//DNA methylation on cytosine;GO:0018022//peptidyl-lysine methylation;GO:0007128//meiotic prophase I;GO:0007281//germ cell development;GO:0007129//synapsis;GO:0034968//histone lysine methylation;GO:0006260//DNA replication gi|557440749|ref|NP_001273502.1|/0/histone-lysine N-methyltransferase EHMT2 isoform c [Mus musculus] 105239 3861.6 28.11 28.7 0.029967283 Up 0.13466095 Rnf44 ring finger protein 44 K19041|1|0.0|667|cge:100750465|E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27] - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - gi|568982880|ref|XP_006517083.1|/0/PREDICTED: RING finger protein 44 isoform X5 [Mus musculus] 68332 987 33.13333333 33.72666667 0.025606387 Up 0.13466095 Sdhaf1 succinate dehydrogenase complex assembly factor 1 K18167|1|1e-51|206|mmu:68332|succinate dehydrogenase assembly factor 1 - - - - 18518 1518 29.32666667 28.74666667 -0.028818423 Down 0.134519914 Igbp1 immunoglobulin (CD79A) binding protein 1 K17606|1|2e-161|571|mmu:18518|immunoglobulin-binding protein 1 GO:0044424 GO:0019901//protein kinase binding;GO:0019888//protein phosphatase regulator activity GO:0032872//regulation of stress-activated MAPK cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0046649//lymphocyte activation;GO:0006915//apoptotic process;GO:0034097//response to cytokine;GO:0006470//protein dephosphorylation;GO:0007018//microtubule-based movement gi|304555605|ref|NP_032810.4|/1.4472e-160/immunoglobulin-binding protein 1 [Mus musculus] 170750 2521 25.67333333 26.25 0.0320468 Up 0.134519914 Xpnpep1 "X-prolyl aminopeptidase (aminopeptidase P) 1, soluble" K01262|1|0.0|1358|mmu:170750|Xaa-Pro aminopeptidase [EC:3.4.11.9] GO:0044444//cytoplasmic part GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0004177//aminopeptidase activity GO:0019538//protein metabolic process;GO:0043171//peptide catabolic process gi|406855427|ref|NP_573479.3|/0/xaa-Pro aminopeptidase 1 [Mus musculus] 20239 4505 25.39666667 24.81333333 -0.0335236 Down 0.134519914 Atxn2 ataxin 2 K03006|1|9e-06|56.2|isc:IscW_ISCW004627|DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0044444//cytoplasmic part GO:0070851//growth factor receptor binding;GO:0019904//protein domain specific binding GO:0031175//neuron projection development;GO:0035264//multicellular organism growth;GO:0042592//homeostatic process;GO:0021533//cell differentiation in hindbrain;GO:0022618//ribonucleoprotein complex assembly;GO:0050877//neurological system process gi|124244104|ref|NP_033151.2|/0/ataxin-2 [Mus musculus] 93670 1248 0.046666667 0.086666667 0.893084796 Up 0.134482305 Tac4 tachykinin 4 K05241|1|7e-60|233|mmu:93670|tachykinin 4 - GO:0005515//protein binding GO:0002279;GO:0046541//saliva secretion;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008015//blood circulation gi|16716383|ref|NP_444323.1|/5.39923e-59/tachykinin-4 precursor [Mus musculus] 78593 3913 0.043333333 0.08 0.884522783 Up 0.134482305 Nrip3 nuclear receptor interacting protein 3 K13215|1|2e-34|151|amj:102565976|nuclear receptor-interacting protein 2 - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|10181148|ref|NP_065635.1|/1.19971e-120/nuclear receptor-interacting protein 3 [Mus musculus] 75285 1034 0.096666667 0.053333333 -0.857980995 Down 0.134482305 4930556N13Rik RIKEN cDNA 4930556N13 gene - - - - - 14176 2449 0.04 0.076666667 0.938599455 Up 0.134482305 Fgf5 fibroblast growth factor 5 K04358|1|1e-89|204|mmu:14176|fibroblast growth factor - GO:0070851//growth factor receptor binding;GO:0005123//death receptor binding;GO:0070851//growth factor receptor binding;GO:0005123//death receptor binding GO:0048522;GO:0030154//cell differentiation;GO:0008283//cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048522;GO:0030154//cell differentiation;GO:0008283//cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|6753854|ref|NP_034333.1|/9.98872e-89/fibroblast growth factor 5 isoform 1 precursor [Mus musculus] 72160 2517 0.043333333 0.08 0.884522783 Up 0.134482305 Tmem163 transmembrane protein 163 - GO:0005769//early endosome;GO:0030672//synaptic vesicle membrane;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding - gi|478499378|ref|XP_004424015.1|/3.77545e-129/PREDICTED: transmembrane protein 163 [Ceratotherium simum simum] 328577 1161 0.08 0.043333333 -0.884522783 Down 0.134482305 7530416G11Rik RIKEN cDNA 7530416G11 gene - - - - gi|366039985|ref|NP_001243001.1|/7.9278e-94/uncharacterized protein LOC328577 [Mus musculus] 278240 1323 0.08 0.043333333 -0.884522783 Down 0.134482305 Spin2c "spindlin family, member 2C" - - - GO:0019953//sexual reproduction;GO:0044763 gi|52851393|ref|NP_001005370.1|/1.73492e-135/spindlin-2C [Mus musculus] 15234 2453.04 0.043333333 0.08 0.884522783 Up 0.134482305 Hgf hepatocyte growth factor K05460|1|1e-117|367|mcf:102133907|hepatocyte growth factor GO:0044421;GO:0044421;GO:0044421;GO:0044421 GO:0004175//endopeptidase activity;GO:0046983//protein dimerization activity;GO:0070851//growth factor receptor binding;GO:0004175//endopeptidase activity;GO:0046983//protein dimerization activity;GO:0070851//growth factor receptor binding;GO:0004175//endopeptidase activity;GO:0046983//protein dimerization activity;GO:0070851//growth factor receptor binding;GO:0004175//endopeptidase activity;GO:0046983//protein dimerization activity;GO:0070851//growth factor receptor binding GO:0006915//apoptotic process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032989;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010823//negative regulation of mitochondrion organization;GO:0043069//negative regulation of programmed cell death;GO:0009967//positive regulation of signal transduction;GO:0016477//cell migration;GO:0001934//positive regulation of protein phosphorylation;GO:0035728//response to hepatocyte growth factor;GO:0006935//chemotaxis;GO:0008283//cell proliferation;GO:0009887//organ morphogenesis;GO:0060638//mesenchymal-epithelial cell signaling;GO:0006915//apoptotic process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032989;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010823//negative regulation of mitochondrion organization;GO:0043069//negative regulation of programmed cell death;GO:0009967//positive regulation of signal transduction;GO:0016477//cell migration;GO:0001934//positive regulation of protein phosphorylation;GO:0035728//response to hepatocyte growth factor;GO:0006935//chemotaxis;GO:0008283//cell proliferation;GO:0009887//organ morphogenesis;GO:0060638//mesenchymal-epithelial cell signaling;GO:0006915//apoptotic process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032989;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010823//negative regulation of mitochondrion organization;GO:0043069//negative regulation of programmed cell death;GO:0009967//positive regulation of signal transduction;GO:0016477//cell migration;GO:0001934//positive regulation of protein phosphorylation;GO:0035728//response to hepatocyte growth factor;GO:0006935//chemotaxis;GO:0008283//cell proliferation;GO:0009887//organ morphogenesis;GO:0060638//mesenchymal-epithelial cell signaling;GO:0006915//apoptotic process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0032989;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010823//negative regulation of mitochondrion organization;GO:0043069//negative regulation of programmed cell death;GO:0009967//positive regulation of signal transduction;GO:0016477//cell migration;GO:0001934//positive regulation of protein phosphorylation;GO:0035728//response to hepatocyte growth factor;GO:0006935//chemotaxis;GO:0008283//cell proliferation;GO:0009887//organ morphogenesis;GO:0060638//mesenchymal-epithelial cell signaling gi|755510865|ref|XP_011248050.1|/0/PREDICTED: hepatocyte growth factor isoform X2 [Mus musculus] 224912 1160 0.05 0.09 0.847996907 Up 0.134482305 Crb3 crumbs family member 3 K06090|1|2e-49|199|mmu:224912|crumbs 3 - - - - 210044 4211 0.093333333 0.05 -0.900464326 Down 0.134482305 Adcy2 adenylate cyclase 2 K08042|1|0.0|2067|mmu:210044|adenylate cyclase 2 [EC:4.6.1.1] GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0044424;GO:0031224//intrinsic component of membrane GO:0032550;GO:0046983//protein dimerization activity;GO:0004016//adenylate cyclase activity;GO:0043169//cation binding;GO:0032403//protein complex binding;GO:0019899//enzyme binding GO:0015980//energy derivation by oxidation of organic compounds;GO:0007267//cell-cell signaling;GO:0038127//ERBB signaling pathway;GO:0045762//positive regulation of adenylate cyclase activity;GO:0033762//response to glucagon;GO:0032147//activation of protein kinase activity;GO:0010863//positive regulation of phospholipase C activity;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0042044//fluid transport gi|124244092|ref|NP_705762.2|/0/adenylate cyclase type 2 [Mus musculus] 12971 1256 0.046666667 0.086666667 0.893084796 Up 0.134482305 Crym "crystallin, mu" K18258|1|2e-174|614|mmu:12971|thiomorpholine-carboxylate dehydrogenase [EC:1.5.1.25] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0016020//membrane "GO:0042562//hormone binding;GO:0003712//transcription cofactor activity;GO:0016646//oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0000166//nucleotide binding" GO:0006575//cellular modified amino acid metabolic process;GO:0050954//sensory perception of mechanical stimulus;GO:0009914//hormone transport;GO:0009719;GO:0014070//response to organic cyclic compound "gi|582045024|pdb|4BV8|A/2.28392e-174/Chain A, Crystal Structure Of The Apo Form Of Mouse Mu-crystallin." 15209 1144 0.05 0.093333333 0.900464326 Up 0.134482305 Hesx1 homeobox gene expressed in ES cells K09354|1|1e-106|388|mmu:15209|homeobox protein expressed in ES cells 1 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding "GO:0007417//central nervous system development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0007423//sensory organ development;GO:0006351//transcription, DNA-templated" "gi|148692776|gb|EDL24723.1|/3.11741e-119/homeobox gene expressed in ES cells, partial [Mus musculus]" 66769 1214 0.086666667 0.046666667 -0.893084796 Down 0.134482305 4933427E11Rik RIKEN cDNA 4933427E11 gene - - - - - 13924 6080 0.04 0.076666667 0.938599455 Up 0.134482305 Ptprv "protein tyrosine phosphatase, receptor type, V" K18036|1|0.0|3330|mmu:13924|receptor-type tyrosine-protein phosphatase V [EC:3.1.3.48] GO:0031224//intrinsic component of membrane GO:0004721//phosphoprotein phosphatase activity "GO:0048771//tissue remodeling;GO:0032868//response to insulin;GO:0033500//carbohydrate homeostasis;GO:0016042//lipid catabolic process;GO:0008283//cell proliferation;GO:0050796//regulation of insulin secretion;GO:0006796//phosphate-containing compound metabolic process;GO:0044773//mitotic DNA damage checkpoint;GO:0012502//induction of programmed cell death;GO:0006464//cellular protein modification process;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0044767//single-organism developmental process" gi|158303304|ref|NP_031981.3|/0/receptor-type tyrosine-protein phosphatase V precursor [Mus musculus] 12516 1052 0.053333333 0.096666667 0.857980995 Up 0.134482305 Cd7 CD7 antigen K06457|1|2e-105|384|mmu:12516|CD7 antigen GO:0031224//intrinsic component of membrane - GO:0001894//tissue homeostasis gi|6806905|ref|NP_033984.1|/1.45437e-104/T-cell antigen CD7 precursor [Mus musculus] 230828 5825 0.09 0.046666667 -0.94753258 Down 0.134482305 Il22ra1 "interleukin 22 receptor, alpha 1" K05138|1|0.0|1181|mmu:230828|interleukin 22 receptor alpha 1 - - - - 12563 8185 0.046666667 0.086666667 0.893084796 Up 0.134482305 Cdh6 cadherin 6 "K06798|1|0.0|1539|mmu:12563|cadherin 6, type 2, K-cadherin" - - - - 75311 1237 0.086666667 0.046666667 -0.893084796 Down 0.134482305 4930550C14Rik RIKEN cDNA 4930550C14 gene - - - - "gi|148693847|gb|EDL25794.1|/0/RIKEN cDNA 4930550C14, isoform CRA_a, partial [Mus musculus]" 432860 2385 0.043333333 0.083333333 0.943416472 Up 0.134482305 B020004C17Rik RIKEN cDNA B020004C17 gene - - - - gi|365906277|ref|NP_001242989.1|/2.0471e-117/uncharacterized protein LOC432860 [Mus musculus] 11676 2681 0.043333333 0.08 0.884522783 Up 0.134482305 Aldoc "aldolase C, fructose-bisphosphate" "K01623|1|0.0|728|mmu:11676|fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection GO:0016832//aldehyde-lyase activity;GO:0005515//protein binding;GO:0016832//aldehyde-lyase activity;GO:0005515//protein binding GO:0006007//glucose catabolic process;GO:0012501//programmed cell death;GO:0009719;GO:0051260//protein homooligomerization;GO:0009887//organ morphogenesis;GO:0051262//protein tetramerization;GO:0006796//phosphate-containing compound metabolic process;GO:0010033//response to organic substance;GO:0006007//glucose catabolic process;GO:0012501//programmed cell death;GO:0051260//protein homooligomerization;GO:0044767//single-organism developmental process;GO:0051262//protein tetramerization;GO:0006796//phosphate-containing compound metabolic process gi|60687506|ref|NP_033787.2|/0/fructose-bisphosphate aldolase C [Mus musculus] 231932 1289 0.083333333 0.043333333 -0.943416472 Down 0.134482305 Gimap7 "GTPase, IMAP family member 7" - - - - "gi|22122705|ref|NP_666279.1|/1.35228e-161/GTPase, IMAP family member 7 [Mus musculus]" 640543 2133 0.05 0.09 0.847996907 Up 0.134482305 Tgm7 transglutaminase 7 K05623|1|0.0|1449|mmu:640543|transglutaminase 7 [EC:2.3.2.13] - "GO:0016755//transferase activity, transferring amino-acyl groups;GO:0043169//cation binding" GO:0006464//cellular protein modification process gi|238018142|ref|NP_001153896.1|/0/protein-glutamine gamma-glutamyltransferase Z [Mus musculus] 244421 3930 1.17 1.083333333 -0.111031312 Down 0.134435293 Lonrf1 LON peptidase N-terminal domain and ring finger 1 K12015|1|2e-08|65.1|xtr:100327256|tripartite motif-containing protein 39 [EC:2.3.2.27];K10667|2|5e-08|63.5|api:100169173|E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27];K15697|3|8e-08|62.8|xma:102231845|RING finger protein 114 [EC:2.3.2.27] - - - gi|124487241|ref|NP_001074619.1|/0/LON peptidase N-terminal domain and RING finger protein 1 [Mus musculus] 70933 2258 1.223333333 1.316666667 0.10607259 Up 0.134435293 4931402G19Rik RIKEN cDNA 4931402G19 gene K12317|1|8e-15|85.1|mmu:76051|neutral alpha-glucosidase C [EC:3.2.1.20] - - - "gi|148696048|gb|EDL27995.1|/2.90752e-65/mCG146020, partial [Mus musculus]" 67556 7569 1.083333333 1.17 0.111031312 Up 0.134435293 Pigm "phosphatidylinositol glycan anchor biosynthesis, class M" "K05284|1|0.0|762|mmu:67556|phosphatidylinositol glycan, class M [EC:2.4.1.-]" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0016757//transferase activity, transferring glycosyl groups" GO:0006497//protein lipidation gi|19920329|ref|NP_080510.1|/0/GPI mannosyltransferase 1 [Mus musculus] 12367 2607.47 1.23 1.14 -0.109624491 Down 0.134435293 Casp3 caspase 3 K02187|1|1e-159|566|mmu:12367|caspase 3 [EC:3.4.22.56] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0016004//phospholipase activator activity;GO:0004175//endopeptidase activity;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0005488//binding;GO:0016004//phospholipase activator activity;GO:0004175//endopeptidase activity;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0005488//binding "GO:0043065//positive regulation of apoptotic process;GO:0009636//response to toxic substance;GO:0044093;GO:0002260//lymphocyte homeostasis;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0050954//sensory perception of mechanical stimulus;GO:0021543//pallium development;GO:0000737//DNA catabolic process, endonucleolytic;GO:0031960//response to corticosteroid;GO:0009416//response to light stimulus;GO:0012502//induction of programmed cell death;GO:0044708//single-organism behavior;GO:0097191//extrinsic apoptotic signaling pathway;GO:0010212//response to ionizing radiation;GO:0042130//negative regulation of T cell proliferation;GO:0000302//response to reactive oxygen species;GO:0030888//regulation of B cell proliferation;GO:0002237//response to molecule of bacterial origin;GO:0001101//response to acid chemical;GO:0043627//response to estrogen;GO:0010038//response to metal ion;GO:0008637//apoptotic mitochondrial changes;GO:0033554//cellular response to stress;GO:0070997//neuron death;GO:0009746;GO:0051604//protein maturation;GO:0030262//apoptotic nuclear changes;GO:0009913//epidermal cell differentiation;GO:0009611//response to wounding;GO:0043065//positive regulation of apoptotic process;GO:0009636//response to toxic substance;GO:0044093;GO:0002260//lymphocyte homeostasis;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0050954//sensory perception of mechanical stimulus;GO:0021543//pallium development;GO:0000737//DNA catabolic process, endonucleolytic;GO:0031960//response to corticosteroid;GO:0009416//response to light stimulus;GO:0012502//induction of programmed cell death;GO:0044708//single-organism behavior;GO:0097191//extrinsic apoptotic signaling pathway;GO:0010212//response to ionizing radiation;GO:0042130//negative regulation of T cell proliferation;GO:0000302//response to reactive oxygen species;GO:0030888//regulation of B cell proliferation;GO:0002237//response to molecule of bacterial origin;GO:0001101//response to acid chemical;GO:0043627//response to estrogen;GO:0010038//response to metal ion;GO:0008637//apoptotic mitochondrial changes;GO:0033554//cellular response to stress;GO:0070997//neuron death;GO:0009746;GO:0051604//protein maturation;GO:0030262//apoptotic nuclear changes;GO:0009913//epidermal cell differentiation;GO:0009611//response to wounding" gi|6753284|ref|NP_033940.1|/9.15928e-159/caspase-3 [Mus musculus] 545389 6930 1.216666667 1.31 0.106632848 Up 0.134435293 Cep170 centrosomal protein 170 K16463|1|0.0|2730|mmu:545389|centrosomal protein CEP170 - - - gi|157278527|ref|NP_001093107.2|/0/centrosomal protein of 170 kDa [Mus musculus] 74351 2814 27.34 26.76666667 -0.030575756 Down 0.134331867 Ddx23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 K12858|1|0.0|1243|rno:300208|ATP-dependent RNA helicase DDX23/PRP28 [EC:3.6.4.13] GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex "GO:0042623//ATPase activity, coupled;GO:0032550" - gi|261337192|ref|NP_001100263.2|/0/probable ATP-dependent RNA helicase DDX23 [Rattus norvegicus] 70350 1855 0.806666667 0.883333333 0.130985312 Up 0.134303659 Basp1 "brain abundant, membrane attached signal protein 1" - - - - gi|344246100|gb|EGW02204.1|/2.2365e-20/hypothetical protein I79_011772 [Cricetulus griseus] 329795 3456 0.933333333 0.85 -0.13492958 Down 0.134303659 Tmem67 transmembrane protein 67 K19348|1|0.0|1935|mmu:329795|meckelin - - - gi|568926871|ref|XP_006538071.1|/0/PREDICTED: meckelin isoform X2 [Mus musculus] 20493 1506 0.953333333 0.87 -0.13196534 Down 0.134303659 Slc10a1 "solute carrier family 10 (sodium/bile acid cotransporter family), member 1" "K14341|1|4e-167|590|mmu:20493|solute carrier family 10 (sodium/bile acid cotransporter), member 1" GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane GO:0005319//lipid transporter activity;GO:0005343//organic acid:sodium symporter activity;GO:0005319//lipid transporter activity;GO:0005343//organic acid:sodium symporter activity GO:0015718//monocarboxylic acid transport;GO:0030001//metal ion transport;GO:0015718//monocarboxylic acid transport;GO:0030001//metal ion transport gi|6755528|ref|NP_035517.1|/2.43546e-168/sodium/bile acid cotransporter isoform 2 [Mus musculus] 93724 5080 0.903333333 0.826666667 -0.127952731 Down 0.134303659 Pcdhga12 "protocadherin gamma subfamily A, 12" K16495|1|0.0|1646|mmu:93724|protocadherin gamma subfamily A GO:0031224//intrinsic component of membrane;GO:0030054//cell junction GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion "gi|18087775|ref|NP_291073.1|/0/protocadherin gamma subfamily A, 12 [Mus musculus]" 15441 4804.57 27.19666667 26.63333333 -0.030196837 Down 0.13422844 Hp1bp3 "heterochromatin protein 1, binding protein 3" K11275|1|2e-08|65.1|aec:105154284|histone H1/5 - - - - 19346 3243 28.01666667 27.45333333 -0.029303989 Down 0.13422844 Rab6a "RAB6A, member RAS oncogene family" K07895|1|1e-122|443|pon:100441942|Ras-related protein Rab-6C;K07893|4|3e-121|439|fab:101820518|Ras-related protein Rab-6A GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0044444//cytoplasmic part;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0012505//endomembrane system;GO:0044444//cytoplasmic part GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008047//enzyme activator activity;GO:0019899//enzyme binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0008047//enzyme activator activity;GO:0019899//enzyme binding "GO:0043462//regulation of ATPase activity;GO:0042221//response to chemical;GO:0015031//protein transport;GO:0009154//purine ribonucleotide catabolic process;GO:0033365//protein localization to organelle;GO:0006479//protein methylation;GO:0046605//regulation of centrosome cycle;GO:0035556//intracellular signal transduction;GO:0007265//Ras protein signal transduction;GO:0043462//regulation of ATPase activity;GO:0042221//response to chemical;GO:0015031//protein transport;GO:0009154//purine ribonucleotide catabolic process;GO:0000301//retrograde transport, vesicle recycling within Golgi;GO:0033365//protein localization to organelle;GO:0006479//protein methylation;GO:0046605//regulation of centrosome cycle" gi|625251293|ref|XP_007616961.1|/9.06754e-135/PREDICTED: LOW QUALITY PROTEIN: ras-related protein Rab-6A isoform X2 [Cricetulus griseus] 76900 1498 25.28666667 25.85 0.03178741 Up 0.13422844 Ssbp4 single stranded DNA binding protein 4 - GO:0043231//intracellular membrane-bounded organelle - - gi|12805361|gb|AAH02150.1|/0/Single stranded DNA binding protein 4 [Mus musculus] 71886 1409.52 31.25333333 30.70666667 -0.025458159 Down 0.1340686 2310002L09Rik RIKEN cDNA 2310002L09 gene - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - "gi|148699109|gb|EDL31056.1|/5.62875e-107/RIKEN cDNA 2310002L09, isoform CRA_a, partial [Mus musculus]" 12527 1306 24.62333333 25.17333333 0.031870187 Up 0.1340686 Cd9 CD9 antigen K06460|1|3e-110|400|mmu:12527|CD9 antigen GO:0031224//intrinsic component of membrane;GO:0044459;GO:0009986//cell surface GO:0005488//binding GO:0007417//central nervous system development;GO:0007043//cell-cell junction assembly;GO:0022610;GO:0021782//glial cell development;GO:0008283//cell proliferation;GO:0006950//response to stress;GO:0007338//single fertilization gi|6680894|ref|NP_031683.1|/2.72323e-109/CD9 antigen [Mus musculus] 74117 2625.17 30.92666667 31.47666667 0.025431424 Up 0.1340686 Actr3 ARP3 actin-related protein 3 K18584|1|0.0|850|cge:100759010|actin-related protein 3 GO:0030055//cell-substrate junction;GO:0015629//actin cytoskeleton;GO:0031252//cell leading edge;GO:0012505//endomembrane system;GO:0045202//synapse;GO:0030055//cell-substrate junction;GO:0015629//actin cytoskeleton;GO:0031252//cell leading edge;GO:0012505//endomembrane system;GO:0045202//synapse;GO:0030055//cell-substrate junction;GO:0015629//actin cytoskeleton;GO:0031252//cell leading edge;GO:0012505//endomembrane system;GO:0045202//synapse GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0032550;GO:0008092//cytoskeletal protein binding GO:0045010//actin nucleation;GO:0010033//response to organic substance;GO:0031038//myosin II filament organization;GO:0009636//response to toxic substance;GO:0031346//positive regulation of cell projection organization;GO:0010591//regulation of lamellipodium assembly;GO:0048858//cell projection morphogenesis;GO:0030182//neuron differentiation;GO:0045010//actin nucleation;GO:0010033//response to organic substance;GO:0031038//myosin II filament organization;GO:0009636//response to toxic substance;GO:0031346//positive regulation of cell projection organization;GO:0010591//regulation of lamellipodium assembly;GO:0048858//cell projection morphogenesis;GO:0030182//neuron differentiation;GO:0045010//actin nucleation;GO:0010033//response to organic substance;GO:0031038//myosin II filament organization;GO:0009636//response to toxic substance;GO:0031346//positive regulation of cell projection organization;GO:0010591//regulation of lamellipodium assembly;GO:0048858//cell projection morphogenesis;GO:0030182//neuron differentiation gi|23956222|ref|NP_076224.1|/0/actin-related protein 3 [Mus musculus] 73649 5208 0.053333333 0.093333333 0.807354922 Up 0.134021588 Cybrd1 cytochrome b reductase 1 K08370|1|6e-146|521|mmu:73649|cytochrome b reductase 1 [EC:1.16.5.1] GO:0005903//brush border;GO:0031224//intrinsic component of membrane "GO:0043169//cation binding;GO:0016723//oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor" GO:0051234//establishment of localization;GO:0044710;GO:0010038//response to metal ion;GO:0006091//generation of precursor metabolites and energy gi|167000071|ref|NP_082869.2|/5.5959e-145/cytochrome b reductase 1 [Mus musculus] 226922 6935 0.046666667 0.083333333 0.836501268 Up 0.134021588 Kcnq5 "potassium voltage-gated channel, subfamily Q, member 5" K04930|1|0.0|1676|mmu:226922|potassium voltage-gated channel KQT-like subfamily member 5 - - - gi|882938967|ref|NP_001297406.1|/0/potassium voltage-gated channel subfamily KQT member 5 isoform 3 [Mus musculus] 16513 5407 0.056666667 0.1 0.819427754 Up 0.134021588 Kcnj10 "potassium inwardly-rectifying channel, subfamily J, member 10" K05003|1|0.0|717|mmu:16513|potassium inwardly-rectifying channel subfamily J member 10 GO:0016021//integral component of membrane;GO:0043234//protein complex;GO:0042995//cell projection;GO:0044459 GO:0032550;GO:0005515//protein binding;GO:0005242//inward rectifier potassium channel activity GO:0055065//metal ion homeostasis;GO:0014003//oligodendrocyte development;GO:0050953//sensory perception of light stimulus;GO:0048168//regulation of neuronal synaptic plasticity;GO:0015813//L-glutamate transport;GO:0071805//potassium ion transmembrane transport;GO:0021545//cranial nerve development;GO:0009416//response to light stimulus;GO:0031960//response to corticosteroid;GO:0019233//sensory perception of pain;GO:0051260//protein homooligomerization;GO:0042391//regulation of membrane potential;GO:0006952//defense response;GO:0051933;GO:0008344//adult locomotory behavior "gi|71534081|gb|AAH99932.1|/0/Kcnj10 protein, partial [Mus musculus]" 442846 1808 0.093333333 0.053333333 -0.807354922 Down 0.134021588 A530050N04Rik RIKEN cDNA A530050N04 gene - - - - "gi|148677827|gb|EDL09774.1|/1.87073e-43/mCG144594, partial [Mus musculus]" 100504591 1082 0.053333333 0.093333333 0.807354922 Up 0.134021588 Gm15987 predicted gene 15987 - - - - "gi|148667488|gb|EDK99904.1|/2.50281e-06/mCG132537, partial [Mus musculus]" 226564 1787 0.093333333 0.053333333 -0.807354922 Down 0.134021588 Fmo4 flavin containing monooxygenase 4 K00485|1|0.0|1119|mmu:226564|dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8] GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane "GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0000166//nucleotide binding" GO:0044237//cellular metabolic process;GO:0044710 gi|568910710|ref|XP_006496836.1|/0/PREDICTED: dimethylaniline monooxygenase [N-oxide-forming] 4 isoform X2 [Mus musculus] 17528 1916 0.056666667 0.1 0.819427754 Up 0.134021588 Mpz myelin protein zero K06770|1|2e-120|435|cfr:102505921|myelin protein zero - - - - 20473 3680 0.083333333 0.046666667 -0.836501268 Down 0.134021588 Six3 sine oculis-related homeobox 3 K19473|1|4e-154|548|hgl:101698303|homeobox protein SIX3/6 GO:0043231//intracellular membrane-bounded organelle "GO:0005515//protein binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0030900//forebrain development;GO:0006886//intracellular protein transport;GO:0007622//rhythmic behavior;GO:0009952//anterior/posterior pattern specification;GO:0002089//lens morphogenesis in camera-type eye gi|1143519|emb|CAA62379.1|/2.10143e-157/SIX3 protein [Mus musculus] 94180 2775 0.053333333 0.093333333 0.807354922 Up 0.134021588 Acsbg1 acyl-CoA synthetase bubblegum family member 1 K15013|1|0.0|1455|mmu:94180|long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3] GO:0042579//microbody;GO:0031982//vesicle GO:0032550;GO:0015645//fatty acid ligase activity GO:0006631//fatty acid metabolic process;GO:0008585//female gonad development;GO:0031960//response to corticosteroid gi|37360022|dbj|BAC97989.1|/0/mKIAA0631 protein [Mus musculus] 622486 2331 0.093333333 0.053333333 -0.807354922 Down 0.134021588 Smok3c sperm motility kinase 3C K08798|1|3e-141|504|cge:100775051|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|894216221|ref|NP_001297632.1|/0/sperm motility kinase 3C [Mus musculus] 269643 4066 0.056666667 0.1 0.819427754 Up 0.134021588 Ppp2r2c "protein phosphatase 2, regulatory subunit B, gamma" K04354|1|0.0|927|oas:101102148|serine/threonine-protein phosphatase 2A regulatory subunit B GO:0008287//protein serine/threonine phosphatase complex GO:0019888//protein phosphatase regulator activity GO:0007154//cell communication "gi|965943289|ref|XP_004010034.2|/0/PREDICTED: protein phosphatase 2, regulatory subunit B, gamma isoform X2 [Ovis aries]" 330958 1205 0.046666667 0.083333333 0.836501268 Up 0.134021588 A730043L09Rik RIKEN cDNA A730043L09 gene - - - - - 278679 2227 0.046666667 0.083333333 0.836501268 Up 0.134021588 Apol7b apolipoprotein L 7b K14480|1|2e-133|479|mmu:278679|apolipoprotein L - - - gi|55153913|gb|AAH85284.1|/1.59003e-132/Apolipoprotein L 7b [Mus musculus] 30056 920.84 8.816666667 8.566666667 -0.041499363 Down 0.134012185 Timm9 translocase of inner mitochondrial membrane 9 K17777|1|3e-45|184|mmu:30056|mitochondrial import inner membrane translocase subunit TIM9 GO:0019866//organelle inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0019866//organelle inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0019866//organelle inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0019866//organelle inner membrane;GO:0005758//mitochondrial intermembrane space GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding GO:0050954//sensory perception of mechanical stimulus;GO:0006626//protein targeting to mitochondrion;GO:0019538//protein metabolic process;GO:0050954//sensory perception of mechanical stimulus;GO:0006626//protein targeting to mitochondrion;GO:0019538//protein metabolic process;GO:0050954//sensory perception of mechanical stimulus;GO:0006626//protein targeting to mitochondrion;GO:0019538//protein metabolic process;GO:0050954//sensory perception of mechanical stimulus;GO:0006626//protein targeting to mitochondrion;GO:0019538//protein metabolic process "gi|148704610|gb|EDL36557.1|/4.88179e-53/translocase of inner mitochondrial membrane 9 homolog (yeast), isoform CRA_b, partial [Mus musculus]" 52120 2679 9.456666667 9.206666667 -0.038652831 Down 0.134012185 Hgsnat heparan-alpha-glucosaminide N-acetyltransferase K10532|1|0.0|1143|mmu:52120|heparan-alpha-glucosaminide N-acetyltransferase [EC:2.3.1.78] GO:0005764//lysosome;GO:0031224//intrinsic component of membrane GO:0008080//N-acetyltransferase activity GO:0006461//protein complex assembly;GO:0007034//vacuolar transport gi|115292433|ref|NP_084160.1|/0/heparan-alpha-glucosaminide N-acetyltransferase [Mus musculus] 76485 2127.23 8.596666667 8.343333333 -0.043153482 Down 0.134012185 Glt8d1 glycosyltransferase 8 domain containing 1 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0016740//transferase activity;GO:0016740//transferase activity - gi|260763885|ref|NP_083902.2|/0/glycosyltransferase 8 domain-containing protein 1 [Mus musculus] 57230 2086 8.73 8.48 -0.041917389 Down 0.134012185 Sap30bp SAP30 binding protein - GO:0005856//cytoskeleton;GO:0031981//nuclear lumen GO:0005488//binding "GO:0012502//induction of programmed cell death;GO:0006351//transcription, DNA-templated" gi|562832888|ref|XP_006145868.1|/3.98694e-123/PREDICTED: SAP30-binding protein isoform X1 [Tupaia chinensis] 100434 3102 8.61 8.356666667 -0.043085647 Down 0.134012185 Slc44a1 "solute carrier family 44, member 1" "K06515|1|0.0|1189|mmu:100434|solute carrier family 44 (choline transporter-like protein), member 1" GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane GO:0015651//quaternary ammonium group transmembrane transporter activity;GO:0015651//quaternary ammonium group transmembrane transporter activity GO:0044763;GO:0006812//cation transport;GO:0044763;GO:0006812//cation transport "gi|148670334|gb|EDL02281.1|/0/solute carrier family 44, member 1, partial [Mus musculus]" 27281 2915 8.63 8.88 0.041199117 Up 0.134012185 Hrasls HRAS-like suppressor K16817|1|8e-36|155|pale:102884995|HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4] GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0042579//microbody GO:0016298//lipase activity GO:0006629//lipid metabolic process;GO:0006996//organelle organization;GO:0018904;GO:0007264//small GTPase mediated signal transduction gi|568995484|ref|XP_006522266.1|/4.93045e-92/PREDICTED: phospholipid-metabolizing enzyme A-C1 isoform X2 [Mus musculus] 69024 1554 9.86 10.11333333 0.036599033 Up 0.134012185 Snx15 sorting nexin 15 K17927|1|3e-158|560|mmu:69024|sorting nexin-15 GO:0012506//vesicle membrane;GO:0031981//nuclear lumen GO:0005543//phospholipid binding GO:0044763;GO:0045184//establishment of protein localization gi|30794430|ref|NP_081188.1|/2.61839e-157/sorting nexin-15 [Mus musculus] 55960 1606 10.18 9.933333333 -0.035387731 Down 0.134012185 Ebag9 estrogen receptor-binding fragment-associated gene 9 - "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031224//intrinsic component of membrane" - GO:0012501//programmed cell death gi|585197232|ref|XP_006749674.1|/1.12748e-110/PREDICTED: receptor-binding cancer antigen expressed on SiSo cells-like isoform X1 [Leptonychotes weddellii] 237403 3456 5.063333333 5.24 0.049479348 Up 0.133918162 Lingo3 leucine rich repeat and Ig domain containing 3 K16360|1|2e-37|160|xtr:100124949|netrin-G3 ligand;K16351|2|2e-36|157|xma:102227794|netrin-G2 ligand - - - "gi|148699538|gb|EDL31485.1|/0/mCG55384, partial [Mus musculus]" 71776 1840 4.81 4.99 0.053002922 Up 0.133918162 Tha1 threonine aldolase 1 K01620|1|0.0|739|mmu:71776|threonine aldolase [EC:4.1.2.48] - - - gi|213512208|ref|NP_082195.2|/0/threonine aldolase 1 [Mus musculus] 231327 4008 5.226666667 5.046666667 -0.050560354 Down 0.133918162 Ppat phosphoribosyl pyrophosphate amidotransferase K00764|1|0.0|1028|mmu:231327|amidophosphoribosyltransferase [EC:2.4.2.14] GO:0044444//cytoplasmic part "GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding;GO:0016763//transferase activity, transferring pentosyl groups" GO:0006541//glutamine metabolic process;GO:0032868//response to insulin;GO:0044772//mitotic cell cycle phase transition;GO:0007589//body fluid secretion;GO:0006188//IMP biosynthetic process;GO:0006144//purine nucleobase metabolic process;GO:0007565//female pregnancy;GO:0042493//response to drug;GO:0009887//organ morphogenesis;GO:0051260//protein homooligomerization gi|74195118|dbj|BAE28301.1|/0/unnamed protein product [Mus musculus] 76779 1595 5.65 5.47 -0.046710035 Down 0.133918162 Cluap1 clusterin associated protein 1 K19684|1|1e-175|618|mmu:76779|clusterin-associated protein 1 GO:0043231//intracellular membrane-bounded organelle - - gi|39930457|ref|NP_084014.1|/1.09817e-174/clusterin-associated protein 1 [Mus musculus] 216618 1523 5.456666667 5.633333333 0.045968925 Up 0.133918162 Cfap36 cilia and flagella associated protein 36 K16742|1|7e-06|54.7|mze:101480557|ADP-ribosylation factor-like protein 2-binding protein - - - - 320011 9045 5.406666667 5.59 0.048108869 Up 0.133918162 Uggt1 UDP-glucose glycoprotein glucosyltransferase 1 K11718|1|0.0|2959|mmu:320011|UDP-glucose:glycoprotein glucosyltransferase [EC:2.4.1.-] GO:0044432 GO:0035251//UDP-glucosyltransferase activity;GO:0005515//protein binding GO:0006458//'de novo' protein folding;GO:0006487//protein N-linked glycosylation "gi|148682526|gb|EDL14473.1|/0/UDP-glucose ceramide glucosyltransferase-like 1, isoform CRA_a, partial [Mus musculus]" 100101806 2516 25.25333333 25.79333333 0.030524398 Up 0.133861747 Srp54c signal recognition particle 54C K03106|1|0.0|963|mmu:100101806|signal recognition particle subunit SRP54 [EC:3.6.5.4] GO:0048500//signal recognition particle;GO:0016604//nuclear body GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0003723//RNA binding;GO:0005048//signal sequence binding GO:0042221//response to chemical;GO:0010467//gene expression;GO:0009154//purine ribonucleotide catabolic process;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0019538//protein metabolic process gi|26354843|dbj|BAC41048.1|/0/unnamed protein product [Mus musculus] 65114 3169 26.51 25.97 -0.029690656 Down 0.133861747 Vps35 VPS35 retromer complex component K18468|1|0.0|1471|mmu:65114|vacuolar protein sorting-associated protein 35 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport gi|13928670|ref|NP_075373.1|/0/vacuolar protein sorting-associated protein 35 [Mus musculus] 83383 2113 1.873333333 1.766666667 -0.084577771 Down 0.133598481 Tfap4 transcription factor AP4 K09108|1|5e-144|486|ocu:100337937|transcription factor AP-4 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0042802//identical protein binding;GO:0019899//enzyme binding" "GO:0006351//transcription, DNA-templated;GO:0071385//cellular response to glucocorticoid stimulus;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0051100//negative regulation of binding;GO:0032897//negative regulation of viral transcription;GO:0007050//cell cycle arrest;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0065003;GO:0000084//mitotic S phase;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0043921" gi|655889180|ref|XP_008247816.1|/4.09075e-143/PREDICTED: LOW QUALITY PROTEIN: transcription factor AP-4 [Oryctolagus cuniculus] 23947 5916 1.893333333 2.006666667 0.083872557 Up 0.133598481 Mid2 midline 2 K10647|1|0.0|1410|ocu:100358558|midline 2 [EC:2.3.2.27] - - - gi|294862469|sp|Q9QUS6.2|TRIM1_MOUSE/0/RecName: Full=Probable E3 ubiquitin-protein ligase MID2; AltName: Full=Midline defect 2; AltName: Full=Midline-2; AltName: Full=Tripartite motif-containing protein 1 218232 4429 1.823333333 1.933333333 0.084512067 Up 0.133598481 Ptpdc1 protein tyrosine phosphatase domain containing 1 K18078|1|0.0|1495|mmu:218232|protein tyrosine phosphatase domain-containing protein 1 [EC:3.1.3.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity GO:0048858//cell projection morphogenesis;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0048858//cell projection morphogenesis;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|74210171|dbj|BAE21357.1|/0/unnamed protein product [Mus musculus] 71991 2107 1.886666667 2 0.084160448 Up 0.133598481 Ercc8 "excision repaiross-complementing rodent repair deficiency, complementation group 8" K10570|1|0.0|811|mmu:71991|DNA excision repair protein ERCC-8 GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0034399//nuclear periphery GO:0005515//protein binding GO:0006289//nucleotide-excision repair;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010212//response to ionizing radiation;GO:0009416//response to light stimulus;GO:0016567//protein ubiquitination gi|110625789|ref|NP_082318.2|/0/DNA excision repair protein ERCC-8 [Mus musculus] 107476 9054 1.95 2.06 0.079170213 Up 0.133598481 Acaca acetyl-Coenzyme A carboxylase alpha K11262|1|0.0|4551|mmu:107476|acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0032550;GO:0016421//CoA carboxylase activity;GO:0043169//cation binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0019842//vitamin binding;GO:0019899//enzyme binding" GO:0015937//coenzyme A biosynthetic process;GO:0010033//response to organic substance;GO:0048878//chemical homeostasis;GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0051260//protein homooligomerization;GO:0019538//protein metabolic process;GO:0048871//multicellular organismal homeostasis gi|568971082|ref|XP_006532016.1|/0/PREDICTED: acetyl-CoA carboxylase 1 isoform X3 [Mus musculus] 100043772 6546 0.06 0.1 0.736965594 Up 0.133589078 Zfp850 zinc finger protein 850 K09228|1|0.0|1441|mmu:100043772|KRAB domain-containing zinc finger protein - - - gi|363807379|ref|NP_001241880.1|/0/zinc finger protein 850 [Mus musculus] 244209 990 0.056666667 0.096666667 0.770518154 Up 0.133589078 Cyp2r1 "cytochrome P450, family 2, subfamily r, polypeptide 1" K07419|1|2e-115|417|rno:361631|vitamin D 25-hydroxylase [EC:1.14.14.24] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0070643;GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0070643" GO:0006066//alcohol metabolic process;GO:0006066//alcohol metabolic process gi|568950651|ref|XP_006507904.1|/2.37867e-138/PREDICTED: vitamin D 25-hydroxylase isoform X4 [Mus musculus] 140493 7617 0.05 0.086666667 0.793549123 Up 0.133589078 Kcnn3 "potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3" K04944|1|0.0|1152|mmu:140493|potassium intermediate/small conductance calcium-activated channel subfamily N member 3 - - - - 243339 2734 0.1 0.06 -0.736965594 Down 0.133589078 Tmem130 transmembrane protein 130 K17304|1|2e-06|57.8|ocu:100347477|melanocyte protein PMEL GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|46048368|ref|NP_808403.2|/0/transmembrane protein 130 precursor [Mus musculus] 71643 7064 0.05 0.086666667 0.793549123 Up 0.133589078 Zgrf1 "zinc finger, GRF-type containing 1" K14326|1|2e-48|198|tsp:Tsp_11650|regulator of nonsense transcripts 1 [EC:3.6.4.-] - - - gi|247494016|ref|NP_932114.2|/0/protein ZGRF1 [Mus musculus] 100043387 1621 0.05 0.086666667 0.793549123 Up 0.133589078 Gm14305 predicted gene 14305 K09228|1|0.0|1083|mmu:100043915|KRAB domain-containing zinc finger protein - - - "gi|123858410|emb|CAM27978.1|/0/novel KRAB box and zinc finger, C2H2 type domain containing protein [Mus musculus]" 212712 5299 0.05 0.086666667 0.793549123 Up 0.133589078 Satb2 special AT-rich sequence binding protein 2 K19774|1|2e-17|95.1|obi:106881402|homeobox domain-containing protein GO:0000785//chromatin;GO:0034399//nuclear periphery;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0001501//skeletal system development;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0048562//embryonic organ morphogenesis;GO:0010033//response to organic substance;GO:0016568//chromatin modification;GO:0016477//cell migration gi|62088332|dbj|BAD92613.1|/0/SATB family member 2 variant [Homo sapiens] 20558 3958 0.056666667 0.096666667 0.770518154 Up 0.133589078 Slfn4 schlafen 4 - - - - gi|84490391|ref|NP_035540.2|/0/schlafen 4 [Mus musculus] 100188919 2124 0.05 0.086666667 0.793549123 Up 0.133589078 Israa immune system released activating agent - - - - - 263764 5799 0.053333333 0.09 0.754887502 Up 0.133589078 Creg2 cellular repressor of E1A-stimulated genes 2 K15704|1|1e-21|109|asn:106723329|E3 ubiquitin-protein ligase RNF149 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity;GO:0032553//ribonucleotide binding GO:0044710 gi|26337933|dbj|BAC32652.1|/2.45966e-149/unnamed protein product [Mus musculus] 18000 3221.08 28.65 28.12666667 -0.026596552 Down 0.133457445 2-Sep septin 2 K16942|1|0.0|681|mmu:18000|septin 2 "GO:0032156//septin cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0005819//spindle;GO:0000775//chromosome, centromeric region;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part;GO:0032156//septin cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0005819//spindle;GO:0000775//chromosome, centromeric region;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part;GO:0032156//septin cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0005819//spindle;GO:0000775//chromosome, centromeric region;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part" GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity GO:0007166//cell surface receptor signaling pathway;GO:0015813//L-glutamate transport;GO:0030030//cell projection organization;GO:0008104//protein localization;GO:0043623//cellular protein complex assembly;GO:0009154//purine ribonucleotide catabolic process;GO:0019222//regulation of metabolic process;GO:0010927;GO:0000087//mitotic M phase;GO:0007166//cell surface receptor signaling pathway;GO:0015813//L-glutamate transport;GO:0030030//cell projection organization;GO:0008104//protein localization;GO:0043623//cellular protein complex assembly;GO:0009154//purine ribonucleotide catabolic process;GO:0019222//regulation of metabolic process;GO:0010927;GO:0000087//mitotic M phase;GO:0007166//cell surface receptor signaling pathway;GO:0015813//L-glutamate transport;GO:0030030//cell projection organization;GO:0008104//protein localization;GO:0043623//cellular protein complex assembly;GO:0009154//purine ribonucleotide catabolic process;GO:0019222//regulation of metabolic process;GO:0010927;GO:0000087//mitotic M phase gi|755493895|ref|XP_011246236.1|/0/PREDICTED: septin-2 isoform X2 [Mus musculus] 320845 1405 1.736666667 1.633333333 -0.088501623 Down 0.133335214 A230056P14Rik RIKEN cDNA A230056P14 gene K19364|1|2e-74|282|ecb:100146592|magnesium transporter NIPA1 - - - - 208518 2576 1.473333333 1.57 0.09168069 Up 0.133335214 Cep78 centrosomal protein 78 K16765|1|0.0|1444|mmu:208518|centrosomal protein CEP78 GO:0005815//microtubule organizing center - - gi|48976076|ref|NP_932136.2|/0/centrosomal protein of 78 kDa [Mus musculus] 22690 4161 1.686666667 1.59 -0.085148119 Down 0.133335214 Zfp28 zinc finger protein 28 K09228|1|0.0|1683|mmu:22690|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|50510925|dbj|BAD32448.1|/0/mKIAA1431 protein [Mus musculus] 72267 3878 1.636666667 1.536666667 -0.090956274 Down 0.133335214 Lrrc8e "leucine rich repeat containing 8 family, member E" K19613|1|2e-24|118|bfo:BRAFLDRAFT_214464|leucine-rich repeat protein SHOC2;K16175|5|1e-22|112|hst:105184576|protein scribble - - - gi|251823957|ref|NP_082451.2|/0/volume-regulated anion channel subunit LRRC8E [Mus musculus] 71566 2929 1.533333333 1.633333333 0.091147888 Up 0.133335214 Clmp CXADR-like membrane protein K06789|1|4e-162|574|mmu:71566|adipocyte-specific adhesion molecule GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex;GO:0005874//microtubule - - gi|31542035|ref|NP_598494.2|/3.84462e-161/CXADR-like membrane protein precursor [Mus musculus] 224523 3174 1.656666667 1.556666667 -0.089823302 Down 0.133335214 4732491K20Rik RIKEN cDNA 4732491K20 gene - - - - - 52392 2738 1.456666667 1.553333333 0.092696675 Up 0.133335214 D1Ertd622e "DNA segment, Chr 1, ERATO Doi 622, expressed" - GO:0031513//nonmotile primary cilium - GO:0045184//establishment of protein localization;GO:0016043//cellular component organization "gi|148707957|gb|EDL39904.1|/4.69094e-121/DNA segment, Chr 1, ERATO Doi 622, expressed, isoform CRA_b, partial [Mus musculus]" 19057 2046.88 22.99333333 22.48333333 -0.032359686 Down 0.133325811 Ppp3cc "protein phosphatase 3, catalytic subunit, gamma isoform" K04348|1|0.0|981|mmu:19057|serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16] - - - - 232679 1836 8.47 8.233333333 -0.040885334 Down 0.13324119 Zc3hc1 "zinc finger, C3HC type 1" - GO:0005635//nuclear envelope GO:0046914//transition metal ion binding;GO:0019900//kinase binding GO:0006915//apoptotic process;GO:0000087//mitotic M phase gi|902763246|ref|NP_001298015.1|/0/nuclear-interacting partner of ALK isoform 1 [Mus musculus] 26558 2445 8.316666667 8.073333333 -0.042840951 Down 0.13324119 Homer3 homer scaffolding protein 3 K15010|1|1e-164|582|mmu:26558|homer - - - - 109978 2384 8.15 8.39 0.041870751 Up 0.13324119 Art4 ADP-ribosyltransferase 4 K06717|1|2e-156|555|mmu:109978|ADP-ribosyltransferase 4 [EC:2.4.2.31] GO:0031224//intrinsic component of membrane "GO:0016763//transferase activity, transferring pentosyl groups" GO:0006486//protein glycosylation gi|13386130|ref|NP_080915.1|/1.44788e-155/ecto-ADP-ribosyltransferase 4 precursor [Mus musculus] 382864 2835 8.323333333 8.083333333 -0.042211074 Down 0.13324119 Colq collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase K12261|1|4e-105|385|cfa:608697|2-hydroxyacyl-CoA lyase 1 [EC:4.1.-.-];K09577|2|4e-42|176|tru:101063589|FK506-binding protein 14 [EC:5.2.1.8] GO:0044420//extracellular matrix component;GO:0005578//proteinaceous extracellular matrix GO:0005539//glycosaminoglycan binding - gi|164519041|ref|NP_034067.2|/7.48159e-154/acetylcholinesterase collagenic tail peptide precursor [Mus musculus] 320640 3997 0.406666667 0.47 0.208814015 Up 0.133109557 Skint4 selection and upkeep of intraepithelial T cells 4 K06712|1|5e-61|239|myb:102252384|butyrophilin;K17270|3|1e-47|194|myd:107184767|myelin-oligodendrocyte glycoprotein GO:0031224//intrinsic component of membrane - - gi|240255629|ref|NP_848901.2|/0/selection and upkeep of intraepithelial T-cells protein 4 [Mus musculus] 67815 2529 0.406666667 0.47 0.208814015 Up 0.133109557 Sec14l2 SEC14-like lipid binding 2 K17981|1|3e-161|571|fch:102055515|mitochondrial fission process protein 1;K16302|2|8e-154|546|tru:101066937|metal transporter CNNM;K01019|3|8e-29|131|umr:103681122|galactosylceramide sulfotransferase [EC:2.8.2.11];K12850|4|2e-17|94.0|tsp:Tsp_07066|pre-mRNA-splicing factor 38B;K19625|5|5e-11|72.8|phi:102114476|retinaldehyde-binding protein 1 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0030234//enzyme regulator activity;GO:0016740//transferase activity "GO:0044093;GO:0051234//establishment of localization;GO:0006351//transcription, DNA-templated;GO:0006695//cholesterol biosynthetic process" gi|21362309|ref|NP_653103.1|/0/SEC14-like protein 2 [Mus musculus] 338351 6153 0.47 0.406666667 -0.208814015 Down 0.133109557 Akap17b A kinase (PRKA) anchor protein 17B "K13169|1|0.0|1657|mmu:338351|splicing factor, arginine/serine-rich 17" - - - gi|126432546|ref|NP_001075425.1|/0/A-kinase anchor protein 17B [Mus musculus] 73610 2391 0.45 0.39 -0.206450877 Down 0.133109557 Zfp433 zinc finger protein 433 K09228|1|0.0|848|mmu:666584|KRAB domain-containing zinc finger protein - - - - 74407 2818 0.283333333 0.23 -0.300866479 Down 0.133100154 Ttc25 tetratricopeptide repeat domain 25 "K01121|1|7e-56|221|shr:100923172|2',3'-cyclic-nucleotide 3'-phosphodiesterase [EC:3.1.4.37];K15837|2|4e-08|63.2|cmk:103174762|G-protein signaling modulator 2;K09527|3|5e-08|62.8|phu:Phum_PHUM462210|DnaJ homolog subfamily C member 7;K09553|4|7e-08|62.4|obi:106868995|stress-induced-phosphoprotein 1" - - - gi|124358957|ref|NP_083194.2|/0/tetratricopeptide repeat protein 25 [Mus musculus] 100503471 993 0.25 0.203333333 -0.298081353 Down 0.133100154 Gm15867 predicted gene 15867 - - - - - 19088 3358 0.246666667 0.2 -0.30256277 Down 0.133100154 Prkar2b "protein kinase, cAMP dependent regulatory, type II beta" K04739|1|0.0|775|mmu:19088|cAMP-dependent protein kinase regulator GO:0005815//microtubule organizing center;GO:0044425;GO:0043234//protein complex;GO:0019866//organelle inner membrane;GO:0044444//cytoplasmic part "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0044389//ubiquitin-like protein ligase binding;GO:0051018//protein kinase A binding;GO:0030551//cyclic nucleotide binding;GO:0019887//protein kinase regulator activity" GO:0009653//anatomical structure morphogenesis;GO:0007611//learning or memory;GO:0010243//response to organonitrogen compound;GO:0007154//cell communication;GO:0001932//regulation of protein phosphorylation;GO:0042493//response to drug;GO:0032787//monocarboxylic acid metabolic process "gi|148704952|gb|EDL36899.1|/0/protein kinase, cAMP dependent regulatory, type II beta, isoform CRA_b, partial [Mus musculus]" 83771 3514 0.286666667 0.233333333 -0.296981738 Down 0.133100154 Tas1r3 "taste receptor, type 1, member 3" K04626|1|0.0|1632|mmu:83771|taste receptor type 1 member 3 GO:0016021//integral component of membrane GO:0005488//binding;GO:0008527//taste receptor activity GO:0050912//detection of chemical stimulus involved in sensory perception of taste;GO:0007166//cell surface receptor signaling pathway gi|13994201|ref|NP_114078.1|/0/taste receptor type 1 member 3 precursor [Mus musculus] 16646 4022 22.32333333 21.82666667 -0.032460646 Down 0.133081349 Kpna1 karyopherin (importin) alpha 1 K15042|1|0.0|987|mmu:16646|importin subunit alpha-1 GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle GO:0022892//substrate-specific transporter activity GO:0006606//protein import into nucleus gi|31543047|ref|NP_032491.2|/0/importin subunit alpha-5 [Mus musculus] 74320 2645.84 24.30666667 24.80666667 0.029375829 Up 0.133081349 Wdr33 WD repeat domain 33 K15542|1|0.0|1191|mmu:74320|polyadenylation factor subunit 2 GO:0005578//proteinaceous extracellular matrix;GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix;GO:0005578//proteinaceous extracellular matrix;GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle - GO:0048232//male gamete generation;GO:0006396//RNA processing;GO:0006281//DNA repair;GO:0006396//RNA processing;GO:0048232//male gamete generation;GO:0006396//RNA processing;GO:0006281//DNA repair gi|284005132|ref|NP_001164437.1|/0/pre-mRNA 3' end processing protein WDR33 isoform 4 [Mus musculus] 16373 2349 20.34666667 20.84333333 0.034793555 Up 0.133081349 Irx3 Iroquois related homeobox 3 K19383|1|5e-09|65.9|soc:105204813|homeobox protein TGIF1;K19553|2|2e-08|64.3|tru:101063546|homeobox protein TGIF2 GO:0044424;GO:0044424 - GO:0030182//neuron differentiation;GO:0030182//neuron differentiation gi|359465568|ref|NP_001240751.1|/3.11798e-134/iroquois-class homeodomain protein IRX-3 isoform 1 [Mus musculus] 69227 3575 23.89333333 23.39 -0.030716275 Down 0.133081349 Selt selenoprotein T - - - - - 13427 2536.72 24.79 25.28333333 0.028428408 Up 0.132836887 Dync1i2 dynein cytoplasmic 1 intermediate chain 2 "K10415|1|0.0|1093|mmu:13427|dynein intermediate chain, cytosolic" GO:0005815//microtubule organizing center;GO:0030286//dynein complex;GO:0005815//microtubule organizing center;GO:0030286//dynein complex;GO:0005815//microtubule organizing center;GO:0030286//dynein complex;GO:0005815//microtubule organizing center;GO:0030286//dynein complex;GO:0005815//microtubule organizing center;GO:0030286//dynein complex;GO:0005815//microtubule organizing center;GO:0030286//dynein complex;GO:0005815//microtubule organizing center;GO:0030286//dynein complex;GO:0005815//microtubule organizing center;GO:0030286//dynein complex GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0051234//establishment of localization;GO:0006928//movement of cell or subcellular component;GO:0051234//establishment of localization;GO:0006928//movement of cell or subcellular component;GO:0051234//establishment of localization;GO:0006928//movement of cell or subcellular component;GO:0051234//establishment of localization;GO:0006928//movement of cell or subcellular component;GO:0051234//establishment of localization;GO:0006928//movement of cell or subcellular component;GO:0051234//establishment of localization;GO:0006928//movement of cell or subcellular component;GO:0051234//establishment of localization;GO:0006928//movement of cell or subcellular component;GO:0051234//establishment of localization;GO:0006928//movement of cell or subcellular component gi|311893380|ref|NP_001185804.1|/0/cytoplasmic dynein 1 intermediate chain 2 isoform 4 [Mus musculus] 15115 1999 23.63333333 24.12333333 0.029606144 Up 0.132836887 Hars histidyl-tRNA synthetase K01892|1|0.0|949|mmu:15115|histidyl-tRNA synthetase [EC:6.1.1.21] GO:0044424 GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550 GO:0006418//tRNA aminoacylation for protein translation "gi|251823891|ref|NP_032240.3|/0/histidine--tRNA ligase, cytoplasmic [Mus musculus]" 27406 3288 23.25666667 23.74333333 0.029878157 Up 0.132836887 Abcf3 "ATP-binding cassette, sub-family F (GCN20), member 3" "K06158|1|0.0|1251|mmu:27406|ATP-binding cassette, subfamily F, member 3" - GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0009154//purine ribonucleotide catabolic process;GO:0002252 gi|29789050|ref|NP_038880.1|/0/ATP-binding cassette sub-family F member 3 [Mus musculus] 320506 3046 0.096666667 0.06 -0.688055994 Down 0.132827485 Lmbrd2 LMBR1 domain containing 2 - GO:0031224//intrinsic component of membrane - - gi|31559855|ref|NP_796152.2|/0/LMBR1 domain-containing protein 2 [Mus musculus] 241624 3143 0.063333333 0.103333333 0.706268797 Up 0.132827485 Exd1 exonuclease 3'-5' domain containing 1 K18740|1|0.0|1088|mmu:241624|exonuclease 3'-5' domain-containing protein 1 GO:0044464 GO:0004527//exonuclease activity GO:0006725//cellular aromatic compound metabolic process gi|27370298|ref|NP_766445.1|/0/exonuclease 3'-5' domain-containing protein 1 [Mus musculus] 20344 3438 0.11 0.066666667 -0.722466024 Down 0.132827485 Selp "selectin, platelet" "K06496|1|0.0|1614|mmu:20344|selectin, platele" GO:0031981//nuclear lumen;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0030667//secretory granule membrane;GO:0044421 GO:0005515//protein binding;GO:0031406//carboxylic acid binding;GO:0005539//glycosaminoglycan binding;GO:0008289//lipid binding;GO:0048029//monosaccharide binding GO:0033622//integrin activation;GO:0010543//regulation of platelet activation;GO:0001568//blood vessel development;GO:0002685//regulation of leukocyte migration;GO:0009967//positive regulation of signal transduction;GO:0007159//leukocyte cell-cell adhesion;GO:0070741//response to interleukin-6;GO:0002237//response to molecule of bacterial origin;GO:0002684//positive regulation of immune system process;GO:0006952//defense response gi|193566|gb|AAA37712.1|/0/granule membrane protein 140 [Mus musculus] 320226 4525 0.063333333 0.103333333 0.706268797 Up 0.132827485 Ccdc171 coiled-coil domain containing 171 K20283|1|5e-27|126|mde:101892550|golgin subfamily A member 4;K11499|3|3e-24|117|pps:100992856|centromere protein F - - - gi|124486602|ref|NP_001074481.1|/0/coiled-coil domain-containing protein 171 [Mus musculus] 50505 6703 3.196666667 3.336666667 0.061839254 Up 0.13280868 Ercc4 "excision repair cross-complementing rodent repair deficiency, complementation group 4" K10848|1|0.0|1787|mmu:50505|DNA excision repair protein ERCC-4 [EC:3.1.-.-] "GO:0000781//chromosome, telomeric region;GO:0005667//transcription factor complex;GO:0000109//nucleotide-excision repair complex" GO:0001091;GO:0004519//endonuclease activity;GO:0043566//structure-specific DNA binding "GO:0000725//recombinational repair;GO:0009411//response to UV;GO:0033683//nucleotide-excision repair, DNA incision;GO:0000723//telomere maintenance" gi|241666402|ref|NP_056584.2|/0/DNA repair endonuclease XPF [Mus musculus] 72873 2190 3.196666667 3.34 0.063279788 Up 0.13280868 Bbof1 basal body orientation factor 1 K20478|1|1e-12|77.8|mde:101889747|golgin subfamily B member 1;K16464|2|2e-08|63.5|phd:102332616|centrosomal protein CEP250;K12478|4|5e-08|62.4|bta:516259|early endosome antigen 1 - - - - 381990 3227 3.42 3.28 -0.06030051 Down 0.13280868 Zbtb2 zinc finger and BTB domain containing 2 K10489|1|0.0|999|mmu:381990|zinc finger and BTB domain-containing protein 2 - - - gi|226423893|ref|NP_001028638.2|/0/zinc finger and BTB domain-containing protein 2 [Mus musculus] 11936 569 3.556666667 3.413333333 -0.059344461 Down 0.13280868 Fxyd2 FXYD domain-containing ion transport regulator 2 K01538|1|6e-27|123|mmu:11936|sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2) GO:0043227//membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0043227//membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0043227//membrane-bounded organelle;GO:0005887//integral component of plasma membrane GO:0005488//binding;GO:0008556//potassium-transporting ATPase activity;GO:0005488//binding;GO:0008556//potassium-transporting ATPase activity;GO:0005488//binding;GO:0008556//potassium-transporting ATPase activity GO:0008283//cell proliferation;GO:0030001//metal ion transport;GO:0008283//cell proliferation;GO:0030001//metal ion transport;GO:0008283//cell proliferation;GO:0030001//metal ion transport gi|16554570|ref|NP_031529.2|/2.67408e-32/sodium/potassium-transporting ATPase subunit gamma isoform a [Mus musculus] 272465 1161 3.47 3.61 0.057063174 Up 0.13280868 Tmem255b transmembrane protein 255B K00909|1|8e-62|239|tru:101076509|rhodopsin kinase [EC:2.7.11.14] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|58476269|gb|AAH89620.1|/0/Fam70b protein, partial [Mus musculus]" 269514 2601.87 3.303333333 3.44 0.058486008 Up 0.13280868 Fbxl4 F-box and leucine-rich repeat protein 4 K10270|1|0.0|1269|mmu:269514|F-box and leucine-rich repeat protein 4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - "gi|149045530|gb|EDL98530.1|/0/F-box and leucine-rich repeat protein 4 (predicted), isoform CRA_b [Rattus norvegicus]" 12799 2333 4.976666667 4.806666667 -0.050143001 Down 0.132761668 Cnp "2',3'-cyclic nucleotide 3' phosphodiesterase" "K01121|1|0.0|850|mmu:12799|2',3'-cyclic-nucleotide 3'-phosphodiesterase [EC:3.1.4.37]" GO:0015630//microtubule cytoskeleton;GO:0031966//mitochondrial membrane;GO:0043209//myelin sheath;GO:0048770;GO:0019866//organelle inner membrane;GO:0042995//cell projection;GO:0044421;GO:0015630//microtubule cytoskeleton;GO:0031966//mitochondrial membrane;GO:0043209//myelin sheath;GO:0048770;GO:0019866//organelle inner membrane;GO:0042995//cell projection;GO:0044421 GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0004112//cyclic-nucleotide phosphodiesterase activity;GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding;GO:0004112//cyclic-nucleotide phosphodiesterase activity GO:0044260;GO:0007626//locomotory behavior;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007420//brain development;GO:0009166//nucleotide catabolic process;GO:0002237//response to molecule of bacterial origin;GO:0006839//mitochondrial transport;GO:0044260;GO:0007626//locomotory behavior;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007420//brain development;GO:0009166//nucleotide catabolic process;GO:0002237//response to molecule of bacterial origin;GO:0006839//mitochondrial transport "gi|226423907|ref|NP_034053.2|/0/2',3'-cyclic-nucleotide 3'-phosphodiesterase isoform 2 [Mus musculus]" 53885 2300.97 4.6 4.773333333 0.053363226 Up 0.132761668 Nphp1 nephronophthisis 1 (juvenile) homolog (human) K19657|1|0.0|1208|mmu:53885|nephrocystin-1 GO:0043296//apical junction complex;GO:0043232;GO:0031513//nonmotile primary cilium;GO:0043296//apical junction complex;GO:0043232;GO:0031513//nonmotile primary cilium;GO:0043296//apical junction complex;GO:0043232;GO:0031513//nonmotile primary cilium - GO:0048869//cellular developmental process;GO:0043010//camera-type eye development;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0016043//cellular component organization;GO:0008104//protein localization;GO:0048869//cellular developmental process;GO:0043010//camera-type eye development;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0016043//cellular component organization;GO:0008104//protein localization;GO:0048869//cellular developmental process;GO:0043010//camera-type eye development;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0016043//cellular component organization;GO:0008104//protein localization gi|597436953|ref|NP_001277942.1|/0/nephrocystin-1 isoform c [Mus musculus] 56468 4460 5.096666667 5.263333333 0.046422764 Up 0.132761668 Socs5 suppressor of cytokine signaling 5 K04698|1|0.0|1048|mmu:56468|suppressor of cytokine signaling 5 GO:0044424 GO:0070851//growth factor receptor binding;GO:0004857//enzyme inhibitor activity GO:0040007//growth;GO:0045064//T-helper 2 cell differentiation;GO:0045063//T-helper 1 cell differentiation;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0031331;GO:0032446//protein modification by small protein conjugation gi|34328249|ref|NP_062628.2|/0/suppressor of cytokine signaling 5 [Mus musculus] 230484 3608 4.493333333 4.663333333 0.053575466 Up 0.132761668 Usp1 ubiquitin specific peptidase 1 K11832|1|0.0|1521|mmu:230484|ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle GO:0016790//thiolester hydrolase activity;GO:0019783//ubiquitin-like protein-specific protease activity GO:0006281//DNA repair;GO:0009416//response to light stimulus;GO:0019941//modification-dependent protein catabolic process;GO:0016579//protein deubiquitination "gi|148698950|gb|EDL30897.1|/0/ubiquitin specific peptidase 1, isoform CRA_c, partial [Mus musculus]" 57444 1037.16 4.423333333 4.593333333 0.054407517 Up 0.132761668 Isg20 interferon-stimulated protein K12579|1|3e-91|337|rno:293052|interferon-stimulated gene 20 kDa protein [EC:3.1.13.1] GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0008296//3'-5'-exodeoxyribonuclease activity;GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0008296//3'-5'-exodeoxyribonuclease activity;GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0008296//3'-5'-exodeoxyribonuclease activity;GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0008296//3'-5'-exodeoxyribonuclease activity GO:0006952//defense response;GO:0051707//response to other organism;GO:0016070//RNA metabolic process;GO:0006308//DNA catabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0042254//ribosome biogenesis;GO:0002252;GO:0006952//defense response;GO:0051707//response to other organism;GO:0016070//RNA metabolic process;GO:0006308//DNA catabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0042254//ribosome biogenesis;GO:0002252;GO:0006952//defense response;GO:0051707//response to other organism;GO:0016070//RNA metabolic process;GO:0006308//DNA catabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0042254//ribosome biogenesis;GO:0002252;GO:0006952//defense response;GO:0051707//response to other organism;GO:0016070//RNA metabolic process;GO:0006308//DNA catabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0042254//ribosome biogenesis;GO:0002252 gi|15805028|ref|NP_065608.2|/1.10153e-99/interferon-stimulated gene 20 kDa protein isoform b [Mus musculus] 72007 6875 5.203333333 5.376666667 0.047275901 Up 0.132761668 Fndc3b fibronectin type III domain containing 3B K12567|1|2e-60|238|sko:102801380|titin [EC:2.7.11.1] GO:0031224//intrinsic component of membrane - GO:0045444//fat cell differentiation gi|170932548|ref|NP_775274.2|/0/fibronectin type III domain-containing protein 3B [Mus musculus] 231872 1194.15 27.83666667 27.35666667 -0.025094012 Down 0.132714656 Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 K15438|1|2e-148|527|mmu:231872|aminoacyl tRNA synthase complex-interacting multifunctional protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0016876//ligase activity, forming aminoacyl-tRNA and related compounds;GO:0016876//ligase activity, forming aminoacyl-tRNA and related compounds" GO:0012501//programmed cell death;GO:0060487//lung epithelial cell differentiation;GO:0016567//protein ubiquitination;GO:0010467//gene expression;GO:0008283//cell proliferation;GO:0012501//programmed cell death;GO:0060487//lung epithelial cell differentiation;GO:0016567//protein ubiquitination;GO:0010467//gene expression;GO:0008283//cell proliferation gi|22122695|ref|NP_666277.1|/3.17846e-150/aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform 2 [Mus musculus] 216974 1529 0.26 0.213333333 -0.285402219 Down 0.132695852 Proca1 protein interacting with cyclin A1 - - - - gi|189037413|sp|B0QZF7.1|PRCA1_MOUSE/1.47163e-112/RecName: Full=Protein PROCA1 226551 6308 1.263333333 1.353333333 0.099281879 Up 0.13264884 Suco SUN domain containing ossification factor - GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane - GO:0034103//regulation of tissue remodeling;GO:0001649//osteoblast differentiation;GO:0010557//positive regulation of macromolecule biosynthetic process gi|254692970|ref|NP_766233.2|/0/SUN domain-containing ossification factor precursor [Mus musculus] 60322 2248 1.346666667 1.253333333 -0.103622631 Down 0.13264884 Chst7 carbohydrate (N-acetylglucosamino) sulfotransferase 7 K04743|1|0.0|809|mmu:60322|chondroitin 6-sulfotransferase 7 [EC:2.8.2.17] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system GO:0034481//chondroitin sulfotransferase activity GO:0006024//glycosaminoglycan biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0005975//carbohydrate metabolic process;GO:1901071 gi|11096336|ref|NP_068361.1|/0/carbohydrate sulfotransferase 7 precursor [Mus musculus] 19716 890 2.73 2.606666667 -0.066694844 Down 0.132620633 Bex1 brain expressed X-linked 1 K12465|1|7e-06|53.5|chx:102171412|nerve growth factor receptor-associated protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005488//binding GO:0006366//transcription from RNA polymerase II promoter;GO:0007405//neuroblast proliferation;GO:0006915//apoptotic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044093;GO:0007049//cell cycle;GO:0030182//neuron differentiation gi|47059482|ref|NP_033078.2|/2.23702e-57/protein BEX1 [Mus musculus] 214498 7110 2.5 2.383333333 -0.068947354 Down 0.132620633 Cdc73 "cell division cycle 73, Paf1/RNA polymerase II complex component" K15175|1|0.0|1009|lve:103069324|parafibromin - - - - 27059 6414 2.59 2.71 0.065340754 Up 0.132620633 Sh3d19 SH3 domain protein D19 K20045|1|4e-30|137|lve:103074694|intersectin - - - gi|755503927|ref|XP_011238437.1|/0/PREDICTED: SH3 domain-containing protein 19 isoform X2 [Mus musculus] 22035 4944 2.4 2.283333333 -0.071892918 Down 0.132620633 Tnfsf10 "tumor necrosis factor (ligand) superfamily, member 10" K04721|1|3e-156|556|mmu:22035|tumor necrosis factor ligand superfamily member 10 - - - - 219181 9416 2.54 2.42 -0.069821449 Down 0.132620633 Akap11 A kinase (PRKA) anchor protein 11 K16527|1|0.0|3302|mmu:219181|A-kinase anchor protein 11 GO:0016020//membrane;GO:0042579//microbody;GO:0032991//macromolecular complex GO:0051018//protein kinase A binding;GO:0030234//enzyme regulator activity GO:0016310//phosphorylation gi|256818808|ref|NP_001157975.1|/0/A-kinase anchor protein 11 [Mus musculus] 14809 3861 2.51 2.393333333 -0.068666021 Down 0.132620633 Grik5 "glutamate receptor, ionotropic, kainate 5 (gamma 2)" "K05205|1|0.0|1801|mcf:102121997|glutamate receptor, ionotropic kainate 5" - - - - 66923 8117 2.626666667 2.51 -0.065545765 Down 0.132620633 Pbrm1 polybromo 1 K11757|1|0.0|2834|mmu:66923|protein polybromo-1 - - - gi|568988497|ref|XP_006519472.1|/0/PREDICTED: protein polybromo-1 isoform X5 [Mus musculus] 68259 4090 1.023333333 0.943333333 -0.117436603 Down 0.132498402 Ift80 intraflagellar transport 80 K19678|1|0.0|1527|mmu:68259|intraflagellar transport protein 80 GO:0005815//microtubule organizing center;GO:0005930//axoneme - GO:0001503//ossification;GO:0048858//cell projection morphogenesis;GO:0007166//cell surface receptor signaling pathway gi|28076907|ref|NP_080917.1|/0/intraflagellar transport protein 80 homolog [Mus musculus] 100038356 3118 1.03 0.95 -0.116644919 Down 0.132498402 Gm15612 predicted gene 15612 K06818|1|1e-22|111|rno:297433|podocalyxin-like 2 - - - - 232855 2772 0.946666667 1.03 0.121715908 Up 0.132498402 Zfp772 zinc finger protein 772 K09228|1|0.0|877|mmu:232855|KRAB domain-containing zinc finger protein - - - gi|110625910|ref|NP_663552.2|/0/zinc finger protein 419 [Mus musculus] 272322 2547 0.69 0.62 -0.154328146 Down 0.132470194 Arntl2 aryl hydrocarbon receptor nuclear translocator-like 2 K09099|1|0.0|1092|mmu:272322|aryl hydrocarbon receptor nuclear translocator-like protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003676//nucleic acid binding;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding GO:0048511//rhythmic process;GO:0007154//cell communication;GO:0006366//transcription from RNA polymerase II promoter;GO:0048511//rhythmic process;GO:0007154//cell communication;GO:0006366//transcription from RNA polymerase II promoter;GO:0048511//rhythmic process;GO:0007154//cell communication;GO:0006366//transcription from RNA polymerase II promoter;GO:0048511//rhythmic process;GO:0007154//cell communication;GO:0006366//transcription from RNA polymerase II promoter gi|26986633|ref|NP_758513.1|/0/aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform 1 [Mus musculus] 89867 4364 0.706666667 0.636666667 -0.150491627 Down 0.132470194 Sec16b SEC16 homolog B (S. cerevisiae) K20353|1|0.0|1845|mmu:89867|COPII coat assembly protein SEC16 GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane - GO:0007031//peroxisome organization;GO:0006901//vesicle coating;GO:0033365//protein localization to organelle;GO:0032527//protein exit from endoplasmic reticulum;GO:0010467//gene expression;GO:0007031//peroxisome organization;GO:0006901//vesicle coating;GO:0033365//protein localization to organelle;GO:0032527//protein exit from endoplasmic reticulum;GO:0010467//gene expression;GO:0007031//peroxisome organization;GO:0006901//vesicle coating;GO:0033365//protein localization to organelle;GO:0032527//protein exit from endoplasmic reticulum;GO:0010467//gene expression gi|50511189|dbj|BAD32580.1|/0/mKIAA1928 protein [Mus musculus] 26564 3987 0.69 0.623333333 -0.146592498 Down 0.132470194 Ror2 receptor tyrosine kinase-like orphan receptor 2 K05123|1|0.0|1697|mmu:26564|receptor tyrosine kinase-like orphan receptor 2 [EC:2.7.10.1] GO:0016021//integral component of membrane GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0001664//G-protein coupled receptor binding "GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0016337//single organismal cell-cell adhesion;GO:0006796//phosphate-containing compound metabolic process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0035567//non-canonical Wnt signaling pathway;GO:0048869//cellular developmental process;GO:0042471//ear morphogenesis;GO:0006464//cellular protein modification process;GO:0035112//genitalia morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0016477//cell migration;GO:0030177//positive regulation of Wnt signaling pathway;GO:0051403//stress-activated MAPK cascade" gi|47271533|ref|NP_038874.3|/0/tyrosine-protein kinase transmembrane receptor ROR2 precursor [Mus musculus] 100038602 712 0.733333333 0.66 -0.152003093 Down 0.132470194 Gm10865 predicted gene 10865 - - - - - 219151 3405 0.69 0.763333333 0.145716831 Up 0.132470194 Scara3 "scavenger receptor class A, member 3" K10062|1|2e-49|201|lcm:102347627|collectin sub-family member 12 GO:0031224//intrinsic component of membrane;GO:0005578//proteinaceous extracellular matrix;GO:0043231//intracellular membrane-bounded organelle - - gi|27369868|ref|NP_766192.1|/0/scavenger receptor class A member 3 [Mus musculus] 13972 3567 0.66 0.73 0.14543044 Up 0.132470194 Gnb1l "guanine nucleotide binding protein (G protein), beta polypeptide 1-like" K14963|1|1e-11|75.1|bfo:BRAFLDRAFT_281422|COMPASS component SWD3;K03130|3|7e-11|72.8|nvi:100122129|transcription initiation factor TFIID subunit 5;K19760|5|2e-10|71.6|mdo:100021179|dynein assembly factor with WDR repeat domains 1 GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424 - GO:0051705;GO:0051705;GO:0051705;GO:0051705;GO:0051705;GO:0051705 gi|625250089|ref|XP_007616351.1|/1.71789e-162/PREDICTED: guanine nucleotide-binding protein subunit beta-like protein 1 isoform X2 [Cricetulus griseus] 108073 4181 0.116666667 0.073333333 -0.669851398 Down 0.132432585 Grm7 "glutamate receptor, metabotropic 7" K04608|1|0.0|1762|mmu:108073|metabotropic glutamate receptor 6/7/8 GO:0031224//intrinsic component of membrane;GO:0033267;GO:0032991//macromolecular complex;GO:0005783//endoplasmic reticulum;GO:0042734//presynaptic membrane;GO:0030425//dendrite;GO:0044297//cell body GO:0010854;GO:0046872//metal ion binding;GO:0005262//calcium channel activity;GO:0042802//identical protein binding;GO:0019904//protein domain specific binding;GO:0001640//adenylate cyclase inhibiting G-protein coupled glutamate receptor activity;GO:0016597//amino acid binding;GO:0016247//channel regulator activity GO:0007631//feeding behavior;GO:0002209//behavioral defense response;GO:0050954//sensory perception of mechanical stimulus;GO:0010941//regulation of cell death;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0007613//memory;GO:0014047//glutamate secretion;GO:0007606//sensory perception of chemical stimulus;GO:0007612//learning;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0006816//calcium ion transport gi|60460877|ref|NP_796302.2|/0/metabotropic glutamate receptor 7 precursor [Mus musculus] 20388 1492 0.063333333 0.1 0.658963082 Up 0.132432585 Sftpb surfactant associated protein B K12382|1|1e-40|170|lcm:102349682|saposin GO:0042599//lamellar body;GO:0000323//lytic vacuole;GO:0005770//late endosome;GO:0044421 - GO:0034614//cellular response to reactive oxygen species;GO:0033273//response to vitamin;GO:0009746;GO:0006643//membrane lipid metabolic process;GO:0048511//rhythmic process;GO:0042592//homeostatic process;GO:0031960//response to corticosteroid;GO:0002237//response to molecule of bacterial origin;GO:0034097//response to cytokine;GO:0044707;GO:0009612//response to mechanical stimulus gi|530678024|ref|NP_001269000.1|/0/pulmonary surfactant-associated protein B isoform 2 precursor [Mus musculus] 100042056 4486 0.073333333 0.116666667 0.669851398 Up 0.132432585 9130019P16Rik RIKEN cDNA 9130019P16 gene - - - - - 100415915 1852 0.063333333 0.1 0.658963082 Up 0.132432585 A530072M11Rik RIKEN cDNA gene A530072M11 - - - - - 74890 942 0.063333333 0.1 0.658963082 Up 0.132432585 Morn3 MORN repeat containing 3 K19755|1|2e-23|111|nvi:100119363|radial spoke head protein 1 - - - gi|110626066|ref|NP_083388.1|/1.37885e-148/MORN repeat-containing protein 3 [Mus musculus] 69371 1268 0.116666667 0.073333333 -0.669851398 Down 0.132432585 Smco2 single-pass membrane protein with coiled-coil domains 2 - GO:0031224//intrinsic component of membrane - - gi|755518919|ref|XP_011239933.1|/0/PREDICTED: single-pass membrane and coiled-coil domain-containing protein 2 isoform X1 [Mus musculus] 228026 5202 25.66 26.12 0.025633726 Up 0.132310354 Pdk1 "pyruvate dehydrogenase kinase, isoenzyme 1" K12077|1|0.0|821|mmu:228026|pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2] GO:0043234//protein complex;GO:0044429 GO:0032550;GO:0004672//protein kinase activity;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity GO:0006979//response to oxidative stress;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0006006//glucose metabolic process "gi|110625975|ref|NP_766253.2|/0/pyruvate dehydrogenase kinase, isozyme 1 precursor [Mus musculus]" 260302 3703 7.64 7.413333333 -0.043450256 Down 0.132263342 Gga3 "golgi associated, gamma adaptin ear containing, ARF binding protein 3" K12404|1|0.0|1162|mmu:260302|ADP-ribosylation factor-binding protein GGA - - - "gi|148702555|gb|EDL34502.1|/0/golgi associated, gamma adaptin ear containing, ARF binding protein 3, isoform CRA_a, partial [Mus musculus]" 14768 4440.2 7.933333333 8.163333333 0.0412312 Up 0.132263342 Lancl1 LanC (bacterial lantibiotic synthetase component C)-like 1 K17509|1|2e-51|207|cqu:CpipJ_CPIJ006058|pyruvate dehydrogenase phosphatase regulatory subunit;K19522|2|3e-41|173|chx:102176212|membrane transport protein XK GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane GO:0070325//lipoprotein particle receptor binding;GO:0046914//transition metal ion binding;GO:0004888//transmembrane signaling receptor activity;GO:0019904//protein domain specific binding;GO:0072341//modified amino acid binding;GO:0070325//lipoprotein particle receptor binding;GO:0046914//transition metal ion binding;GO:0004888//transmembrane signaling receptor activity;GO:0019904//protein domain specific binding;GO:0072341//modified amino acid binding;GO:0070325//lipoprotein particle receptor binding;GO:0046914//transition metal ion binding;GO:0004888//transmembrane signaling receptor activity;GO:0019904//protein domain specific binding;GO:0072341//modified amino acid binding GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway "gi|148667829|gb|EDL00246.1|/0/LanC (bacterial lantibiotic synthetase component C)-like 1, isoform CRA_b, partial [Mus musculus]" 52513 3287 8.066666667 8.3 0.041138695 Up 0.132263342 Ddx56 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 K14810|1|0.0|975|mmu:52513|ATP-dependent RNA helicase DDX56/DBP9 [EC:3.6.4.13] GO:0031981//nuclear lumen "GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity" GO:0042254//ribosome biogenesis gi|21312650|ref|NP_080814.1|/0/probable ATP-dependent RNA helicase DDX56 [Mus musculus] 74145 3879 8.856666667 9.086666667 0.036987334 Up 0.132263342 F13a1 "coagulation factor XIII, A1 subunit" K03917|1|0.0|1472|mmu:74145|coagulation factor XIII A1 polypeptide [EC:2.3.2.13] GO:0044424;GO:0044424 "GO:0043169//cation binding;GO:0016755//transferase activity, transferring amino-acyl groups;GO:0043169//cation binding;GO:0016755//transferase activity, transferring amino-acyl groups" GO:0007599//hemostasis;GO:0009611//response to wounding;GO:0006464//cellular protein modification process;GO:0007599//hemostasis;GO:0009611//response to wounding;GO:0006464//cellular protein modification process "gi|148708973|gb|EDL40919.1|/0/coagulation factor XIII, A1 subunit, isoform CRA_c, partial [Mus musculus]" 224023 2633 9.236666667 9.47 0.035992121 Up 0.132263342 Klhl22 kelch-like 22 K10459|1|0.0|1305|mmu:224023|kelch-like protein 22 - - - - 101612 1905 7.773333333 7.54 -0.043968859 Down 0.132263342 Grwd1 glutamate-rich WD repeat containing 1 K14848|1|0.0|890|mmu:101612|ribosome assembly protein RRB1 GO:0031981//nuclear lumen - - gi|163937861|ref|NP_700468.2|/0/glutamate-rich WD repeat-containing protein 1 [Mus musculus] 234378 3021.69 7.453333333 7.683333333 0.043846562 Up 0.132263342 Klhl26 kelch-like 26 K10463|1|0.0|1122|mmu:234378|kelch-like protein 26 - - - "gi|148696872|gb|EDL28819.1|/0/kelch-like 26 (Drosophila), isoform CRA_c, partial [Mus musculus]" 52837 5162 8.29 8.52 0.039481329 Up 0.132263342 Tmx4 thioredoxin-related transmembrane protein 4 K16458|1|2e-26|124|hmg:100199716|centrosomal protein CEP104;K09585|2|3e-09|68.2|pxy:105386433|thioredoxin domain-containing protein 10 [EC:5.3.4.1];K13984|4|3e-07|61.2|tca:660338|thioredoxin domain-containing protein 5;K09582|5|5e-07|60.5|loa:LOAG_03754|protein disulfide-isomerase A4 [EC:5.3.4.1] GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy;GO:0019725//cellular homeostasis gi|37360266|dbj|BAC98111.1|/1.31232e-162/mKIAA1162 protein [Mus musculus] 13537 1630 0.216666667 0.263333333 0.281412935 Up 0.132235135 Dusp2 dual specificity phosphatase 2 K04459|1|1e-153|545|mmu:13537|dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] - - - gi|46560573|ref|NP_034220.2|/1.21841e-152/dual specificity protein phosphatase 2 [Mus musculus] 17865 3702 0.303333333 0.25 -0.27897595 Down 0.132235135 Mybl2 myeloblastosis oncogene-like 2 K09421|1|0.0|1289|mmu:17865|myb-related protein GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0007052//mitotic spindle organization;GO:0006351//transcription, DNA-templated" gi|6678974|ref|NP_032678.1|/0/myb-related protein B [Mus musculus] 319997 1936 0.303333333 0.25 -0.27897595 Down 0.132235135 A630001G21Rik RIKEN cDNA A630001G21 gene K15413|1|2e-26|123|pale:102897738|nuclear autoantigen Sp-100 - - - "gi|148708311|gb|EDL40258.1|/5.08795e-124/mCG8524, isoform CRA_a, partial [Mus musculus]" 239833 4111 0.236666667 0.286666667 0.276517635 Up 0.132235135 Lmln leishmanolysin-like (metallopeptidase M8 family) K13539|1|0.0|1269|mmu:239833|leishmanolysin-like peptidase [EC:3.4.24.-] GO:0044424 GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0019538//protein metabolic process;GO:0022610;GO:0000087//mitotic M phase "gi|148665419|gb|EDK97835.1|/0/leishmanolysin-like (metallopeptidase M8 family), isoform CRA_c, partial [Mus musculus]" 70753 2219 0.25 0.303333333 0.27897595 Up 0.132235135 6330415B21Rik RIKEN cDNA 6330415B21 gene - - - - gi|74226601|dbj|BAE23951.1|/1.55373e-79/unnamed protein product [Mus musculus] 16323 1529 0.396666667 0.456666667 0.20321432 Up 0.132197525 Inhba inhibin beta-A "K04667|1|0.0|795|mmu:16323|inhibin, beta" GO:0048180;GO:0043511 GO:0070697//activin receptor binding;GO:0042277//peptide binding;GO:0046983//protein dimerization activity GO:0032277//negative regulation of gonadotropin secretion;GO:0032924//activin receptor signaling pathway;GO:0001553//luteinization;GO:0001707//mesoderm formation;GO:0051726//regulation of cell cycle;GO:0016049//cell growth;GO:0044772//mitotic cell cycle phase transition;GO:0008544//epidermis development;GO:0001934//positive regulation of protein phosphorylation;GO:0012502//induction of programmed cell death;GO:0042036//negative regulation of cytokine biosynthetic process;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0036315//cellular response to sterol;GO:0043010//camera-type eye development;GO:0032278;GO:0030183//B cell differentiation;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0020027//hemoglobin metabolic process;GO:0006950//response to stress;GO:0030218//erythrocyte differentiation;GO:0032354//response to follicle-stimulating hormone;GO:0030728//ovulation;GO:0009887//organ morphogenesis gi|966933071|ref|XP_014989160.1|/0/PREDICTED: inhibin beta A chain isoform X1 [Macaca mulatta] 19266 9127 0.49 0.426666667 -0.199672345 Down 0.132197525 Ptprd "protein tyrosine phosphatase, receptor type, D" K06777|1|0.0|2964|mmu:19266|receptor-type tyrosine-protein phosphatase delta [EC:3.1.3.48] GO:0031224//intrinsic component of membrane GO:0005515//protein binding;GO:0004721//phosphoprotein phosphatase activity GO:0006470//protein dephosphorylation;GO:0016337//single organismal cell-cell adhesion;GO:0007416//synapse assembly;GO:0031346//positive regulation of cell projection organization;GO:0030154//cell differentiation gi|90403603|ref|NP_035341.2|/0/receptor-type tyrosine-protein phosphatase delta precursor [Mus musculus] 14048 4312.68 0.413333333 0.473333333 0.195550809 Up 0.132197525 Eya1 EYA transcriptional coactivator and phosphatase 1 K15616|1|0.0|974|mmu:14048|eyes absent homolog 1 [EC:3.1.3.48] - - - - 28250 3847 0.113333333 0.073333333 -0.628031223 Down 0.132112904 Slco1a4 "solute carrier organic anion transporter family, member 1a4" "K03460|1|0.0|1308|mmu:28250|solute carrier organic anion transporter family, member 1A" GO:0016021//integral component of membrane;GO:0005903//brush border;GO:0044459 GO:0015291//secondary active transmembrane transporter activity;GO:0046943//carboxylic acid transmembrane transporter activity;GO:0005319//lipid transporter activity GO:0048545//response to steroid hormone;GO:0009914//hormone transport;GO:0009887//organ morphogenesis;GO:0080184//response to phenylpropanoid;GO:0015718//monocarboxylic acid transport;GO:0022600//digestive system process gi|13507614|ref|NP_109612.1|/0/solute carrier organic anion transporter family member 1A4 [Mus musculus] 26887 2000 0.08 0.123333333 0.624490865 Up 0.132112904 Chst4 carbohydrate (chondroitin 6/keratan) sulfotransferase 4 K04746|1|0.0|744|mmu:26887|carbohydrate 6-sulfotransferase 4 [EC:2.8.2.-] - - - - 14807 8860 0.073333333 0.11 0.584962501 Up 0.132112904 Grik3 "glutamate receptor, ionotropic, kainate 3" "K05203|1|0.0|1802|mmu:14807|glutamate receptor, ionotropic kainate 3" GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0033267;GO:0097060//synaptic membrane;GO:0043025//neuronal cell body GO:0005488//binding;GO:0004970//ionotropic glutamate receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity "GO:0035249//synaptic transmission, glutamatergic;GO:0007215//glutamate receptor signaling pathway;GO:0044765//single-organism transport;GO:0006873//cellular ion homeostasis;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway" "gi|124487364|ref|NP_001074566.1|/0/glutamate receptor ionotropic, kainate 3 precursor [Mus musculus]" 12467 1817 0.086666667 0.13 0.584962501 Up 0.132112904 Cct6b "chaperonin containing Tcp1, subunit 6b (zeta)" K09498|1|0.0|990|mmu:12467|T-complex protein 1 subunit zeta GO:0043234//protein complex;GO:0044424;GO:0043234//protein complex;GO:0044424 GO:0005515//protein binding;GO:0032550;GO:0005515//protein binding;GO:0032550 GO:0044267//cellular protein metabolic process;GO:0044267//cellular protein metabolic process gi|226693361|ref|NP_033969.2|/0/T-complex protein 1 subunit zeta-2 isoform 1 [Mus musculus] 226419 2072 0.073333333 0.113333333 0.628031223 Up 0.132112904 Dyrk3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 K18669|1|0.0|1110|mmu:226419|dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding GO:0006464//cellular protein modification process;GO:0030099//myeloid cell differentiation;GO:0006796//phosphate-containing compound metabolic process gi|21704000|ref|NP_663483.1|/0/dual specificity tyrosine-phosphorylation-regulated kinase 3 [Mus musculus] 226518 4548 0.073333333 0.11 0.584962501 Up 0.132112904 Nmnat2 nicotinamide nucleotide adenylyltransferase 2 K06210|1|2e-172|609|mmu:226518|nicotinamide mononucleotide adenylyltransferase [EC:2.7.7.1 2.7.7.18] - - - - 71111 2690 0.113333333 0.073333333 -0.628031223 Down 0.132112904 Gpr39 G protein-coupled receptor 39 K08412|1|0.0|891|mmu:71111|G protein-coupled receptor 39 GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0033500//carbohydrate homeostasis;GO:0001696//gastric acid secretion;GO:0010043//response to zinc ion;GO:0006629//lipid metabolic process;GO:0007631//feeding behavior;GO:0035482//gastric motility;GO:0055092//sterol homeostasis;GO:0032024//positive regulation of insulin secretion gi|226442795|ref|NP_081953.2|/0/G-protein coupled receptor 39 [Mus musculus] 11890 1366 0.073333333 0.113333333 0.628031223 Up 0.132112904 Asgr2 asialoglycoprotein receptor 2 K10064|1|1e-130|468|mmu:11890|asialoglycoprotein receptor 2 GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0048878//chemical homeostasis;GO:0019538//protein metabolic process;GO:0010608//posttranscriptional regulation of gene expression;GO:0001503//ossification gi|6680734|ref|NP_031519.1|/1.69975e-157/asialoglycoprotein receptor 2 isoform a [Mus musculus] 637515 4131 0.07 0.106666667 0.607682577 Up 0.132112904 Nlrp1b "NLR family, pyrin domain containing 1B" "K12798|1|0.0|2353|mmu:637515|NACHT, LRR and PYD domains-containing protein 1" GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043234//protein complex GO:0032550;GO:0005515//protein binding;GO:0032550;GO:0005515//protein binding GO:0070997//neuron death;GO:1901652//response to peptide;GO:0006915//apoptotic process;GO:0032731//positive regulation of interleukin-1 beta production;GO:0012502//induction of programmed cell death;GO:0006952//defense response;GO:0070997//neuron death;GO:1901652//response to peptide;GO:0006915//apoptotic process;GO:0032731//positive regulation of interleukin-1 beta production;GO:0012502//induction of programmed cell death;GO:0006952//defense response "gi|241666419|ref|NP_001155886.1|/0/NLR family, pyrin domain containing 1B isoform 3 [Mus musculus]" 329941 4331 0.083333333 0.126666667 0.604071324 Up 0.132112904 Col8a2 "collagen, type VIII, alpha 2" "K19479|1|1e-46|191|gja:107108602|collagen, type X, alpha" - - GO:0044699 "gi|148698346|gb|EDL30293.1|/5.31302e-101/procollagen, type VIII, alpha 2 [Mus musculus]" 67171 2718 23.09 22.64333333 -0.02818182 Down 0.13205649 Dram2 DNA-damage regulated autophagy modulator 2 - GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane - GO:0012502//induction of programmed cell death;GO:0012502//induction of programmed cell death;GO:0012502//induction of programmed cell death;GO:0012502//induction of programmed cell death "gi|148669930|gb|EDL01877.1|/2.73607e-163/transmembrane protein 77, isoform CRA_c, partial [Mus musculus]" 21407 949 21.67 21.21666667 -0.03050114 Down 0.13205649 Tcf15 transcription factor 15 K09070|1|1e-82|308|rno:296272|transcription factor 15 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0005515//protein binding "GO:0007498//mesoderm development;GO:0003002//regionalization;GO:0050905//neuromuscular process;GO:0007423//sensory organ development;GO:0008544//epidermis development;GO:0009887//organ morphogenesis;GO:0001501//skeletal system development;GO:0006351//transcription, DNA-templated;GO:0007631//feeding behavior" gi|568916160|ref|XP_006499163.1|/8.28259e-85/PREDICTED: transcription factor 15 isoform X1 [Mus musculus] 93842 4163.8 0.24 0.29 0.273018494 Up 0.131906051 Igsf9 "immunoglobulin superfamily, member 9" K19511|1|3e-28|130|cin:100185463|peroxidase [EC:1.11.1.7];K17341|4|4e-27|127|clv:102096075|hemicentin GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane - GO:0031175//neuron projection development;GO:0031175//neuron projection development "gi|148707064|gb|EDL39011.1|/0/immunoglobulin superfamily, member 9, isoform CRA_a, partial [Mus musculus]" 79456 3922 0.32 0.266666667 -0.263034406 Down 0.13178382 Recql4 RecQ protein-like 4 K10730|1|0.0|2368|mmu:79456|ATP-dependent DNA helicase Q4 [EC:3.6.4.12] - - - - 71270 1693 0.326666667 0.273333333 -0.257157839 Down 0.13178382 4933438K21Rik RIKEN cDNA 4933438K21 gene - GO:0043005//neuron projection;GO:0044421 GO:0032934//sterol binding;GO:0042802//identical protein binding;GO:0071813//lipoprotein particle binding GO:0009611//response to wounding;GO:0010742//macrophage derived foam cell differentiation;GO:0051592//response to calcium ion;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0043623//cellular protein complex assembly;GO:0097305//response to alcohol;GO:0010976//positive regulation of neuron projection development;GO:0010883//regulation of lipid storage gi|1791243|gb|AAB41224.1|/1.48412e-47/ORF2 [Rattus norvegicus] 320484 3677 0.236666667 0.283333333 0.259643817 Up 0.13178382 Rasal3 RAS protein activator like 3 K17634|1|0.0|1848|mmu:320484|RAS protein activator-like 3 GO:0044464 GO:0008289//lipid binding GO:0007264//small GTPase mediated signal transduction gi|130502228|ref|NP_848900.2|/0/RAS protein activator like-3 [Mus musculus] 15437 1683 0.233333333 0.28 0.263034406 Up 0.13178382 Hoxd8 homeobox D8 K09308|1|2e-74|282|mmu:15437|homeobox protein HoxB/C/D8 - - - gi|112807184|ref|NP_032302.2|/5.31557e-119/homeobox protein Hox-D8 isoform a [Mus musculus] 74185 2988 19.08333333 19.52666667 0.0331325 Up 0.131736808 Gbe1 "glucan (1,4-alpha-), branching enzyme 1" "K00700|1|0.0|1457|mmu:74185|1,4-alpha-glucan branching enzyme [EC:2.4.1.18]" GO:0044444//cytoplasmic part "GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0043167//ion binding;GO:0016758//transferase activity, transferring hexosyl groups" GO:0005977//glycogen metabolic process;GO:0019318//hexose metabolic process "gi|17975508|ref|NP_083079.1|/0/1,4-alpha-glucan-branching enzyme [Mus musculus]" 20256 1970 0.523333333 0.46 -0.186096292 Down 0.131642785 Clec11a "C-type lectin domain family 11, member a" K17521|1|2e-149|532|mmu:20256|C-type lectin domain family 11 member A GO:0005815//microtubule organizing center GO:0005102//receptor binding GO:0008283//cell proliferation gi|6677869|ref|NP_033157.1|/1.35914e-148/C-type lectin domain family 11 member A precursor [Mus musculus] 110962 4046 19.16333333 18.73333333 -0.0327409 Down 0.131473542 Mbd6 methyl-CpG binding domain protein 6 K03652|1|6e-41|172|chx:102185136|DNA-3-methyladenine glycosylase [EC:3.2.2.21] - - - gi|70778938|ref|NP_149063.2|/1.05941e-103/methyl-CpG-binding domain protein 6 [Mus musculus] 215951 2530 20.76 21.19333333 0.029804072 Up 0.131473542 Lace1 lactation elevated 1 K18798|1|0.0|902|mmu:215951|peroxisome-assembly ATPase [EC:3.6.4.7] GO:0043231//intracellular membrane-bounded organelle GO:0032550 - gi|144922663|ref|NP_665686.2|/0/lactation elevated protein 1 [Mus musculus] 26416 3433.34 24.27333333 23.84333333 -0.025786299 Down 0.131473542 Mapk14 mitogen-activated protein kinase 14 K04441|1|5e-173|611|ngi:103739660|p38 MAP kinase [EC:2.7.11.24] GO:0031981//nuclear lumen;GO:0005829//cytosol;GO:0005819//spindle;GO:0031981//nuclear lumen;GO:0005829//cytosol;GO:0005819//spindle;GO:0000785//chromatin;GO:0031981//nuclear lumen;GO:0005829//cytosol;GO:0005819//spindle;GO:0000785//chromatin "GO:0008134//transcription factor binding;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0032550;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0032550;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0032550;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding" "GO:0001775//cell activation;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0042692//muscle cell differentiation;GO:0010595//positive regulation of endothelial cell migration;GO:0019318//hexose metabolic process;GO:0032989;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0014706//striated muscle tissue development;GO:0072593//reactive oxygen species metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0010212//response to ionizing radiation;GO:0007599//hemostasis;GO:0006606//protein import into nucleus;GO:0007264//small GTPase mediated signal transduction;GO:0002237//response to molecule of bacterial origin;GO:1901652//response to peptide;GO:0006366//transcription from RNA polymerase II promoter;GO:0071363//cellular response to growth factor stimulus;GO:0002573//myeloid leukocyte differentiation;GO:0009746;GO:0090398//cellular senescence;GO:0030218//erythrocyte differentiation;GO:0000165//MAPK cascade;GO:0012501//programmed cell death;GO:0006468//protein phosphorylation;GO:0006355//regulation of transcription, DNA-templated;GO:0048255//mRNA stabilization;GO:0006631//fatty acid metabolic process;GO:0001775//cell activation;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0010595//positive regulation of endothelial cell migration;GO:0019318//hexose metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016358//dendrite development;GO:0008016//regulation of heart contraction;GO:0072593//reactive oxygen species metabolic process;GO:0007005//mitochondrion organization;GO:0051592//response to calcium ion;GO:0006974//cellular response to DNA damage stimulus;GO:0010212//response to ionizing radiation;GO:0007599//hemostasis;GO:0006606//protein import into nucleus;GO:0007264//small GTPase mediated signal transduction;GO:0002237//response to molecule of bacterial origin;GO:1901652//response to peptide;GO:0006366//transcription from RNA polymerase II promoter;GO:0071363//cellular response to growth factor stimulus;GO:0055003//cardiac myofibril assembly;GO:0002573//myeloid leukocyte differentiation;GO:0009746;GO:0090398//cellular senescence;GO:0030218//erythrocyte differentiation;GO:0000165//MAPK cascade;GO:0012501//programmed cell death;GO:0006468//protein phosphorylation;GO:0006355//regulation of transcription, DNA-templated;GO:0048255//mRNA stabilization;GO:0006631//fatty acid metabolic process;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0010595//positive regulation of endothelial cell migration;GO:0019318//hexose metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016358//dendrite development;GO:0008016//regulation of heart contraction;GO:0072593//reactive oxygen species metabolic process;GO:0007005//mitochondrion organization;GO:0051592//response to calcium ion;GO:0006974//cellular response to DNA damage stimulus;GO:0010212//response to ionizing radiation;GO:0006606//protein import into nucleus;GO:0002237//response to molecule of bacterial origin;GO:1901652//response to peptide;GO:0006366//transcription from RNA polymerase II promoter;GO:0071363//cellular response to growth factor stimulus;GO:0055003//cardiac myofibril assembly;GO:0002573//myeloid leukocyte differentiation;GO:0009746;GO:0090398//cellular senescence;GO:0030218//erythrocyte differentiation;GO:0000165//MAPK cascade;GO:0012501//programmed cell death;GO:0006468//protein phosphorylation;GO:0006631//fatty acid metabolic process" "gi|148690640|gb|EDL22587.1|/7.36663e-174/mitogen activated protein kinase 14, isoform CRA_d, partial [Mus musculus]" 72562 574 18.06333333 18.49666667 0.034201156 Up 0.131473542 Pcbd2 pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 K01724|1|1e-62|240|mmu:72562|4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0016836//hydro-lyase activity "GO:0044710;GO:0009108//coenzyme biosynthetic process;GO:0051260//protein homooligomerization;GO:0006351//transcription, DNA-templated" gi|52421794|ref|NP_082557.1|/9.59131e-62/pterin-4-alpha-carbinolamine dehydratase 2 [Mus musculus] 17766 939 4.45 4.29 -0.052827688 Down 0.131398323 Nudt1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 K17816|1|1e-69|265|mmu:17766|8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56] GO:0031982//vesicle;GO:0005635//nuclear envelope;GO:0044429 GO:0043169//cation binding;GO:0047429//nucleoside-triphosphate diphosphatase activity;GO:0003723//RNA binding GO:0009155;GO:0006259//DNA metabolic process;GO:0009154//purine ribonucleotide catabolic process "gi|6678950|ref|NP_032663.1|/1.06803e-68/7,8-dihydro-8-oxoguanine triphosphatase precursor [Mus musculus]" 105670 3578.06 4.62 4.78 0.049117767 Up 0.131398323 Rcbtb2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 K11494|1|0.0|1097|mmu:105670|RCC1 and BTB domain-containing protein - - - "gi|148703915|gb|EDL35862.1|/0/regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2, isoform CRA_b, partial [Mus musculus]" 74120 3242 4.623333333 4.466666667 -0.049734787 Down 0.131398323 Zfp263 zinc finger protein 263 K09229|1|0.0|1374|mmu:74120|KRAB and SCAN domains-containing zinc finger protein - - - gi|188219539|ref|NP_683726.2|/0/zinc finger protein 263 [Mus musculus] 78832 5808 5.006666667 4.843333333 -0.04785011 Down 0.131398323 Cacul1 "CDK2 associated, cullin domain 1" K16449|1|2e-56|224|bfo:BRAFLDRAFT_84869|regulator of G-protein signaling;K03869|2|1e-06|59.3|hmg:100202538|cullin 3 GO:0000151//ubiquitin ligase complex;GO:0000151//ubiquitin ligase complex GO:0019900//kinase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0019900//kinase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0019900//kinase binding GO:0044763;GO:0019941//modification-dependent protein catabolic process;GO:0001934//positive regulation of protein phosphorylation;GO:0008283//cell proliferation;GO:0044772//mitotic cell cycle phase transition;GO:0019941//modification-dependent protein catabolic process;GO:0001934//positive regulation of protein phosphorylation;GO:0008283//cell proliferation;GO:0044772//mitotic cell cycle phase transition;GO:0001934//positive regulation of protein phosphorylation;GO:0008283//cell proliferation gi|285402250|ref|NP_001165568.1|/1.07215e-117/CDK2-associated and cullin domain-containing protein 1 isoform 3 [Mus musculus] 50873 2182.88 5.003333333 4.843333333 -0.046889274 Down 0.131398323 Park2 "Parkinson disease (autosomal recessive, juvenile) 2, parkin" K04556|1|0.0|994|mmu:50873|parkin [EC:2.3.2.27] - - - - 76719 5510 7.086666667 7.31 0.044764215 Up 0.131351311 Kansl1 KAT8 regulatory NSL complex subunit 1 K18400|1|0.0|1835|mmu:76719|KAT8 regulatory NSL complex subunit 1 GO:0044665//MLL1/2 complex - GO:0043967//histone H4 acetylation gi|124486668|ref|NP_001074514.1|/0/KAT8 regulatory NSL complex subunit 1 [Mus musculus] 11432 4669 8.343333333 8.566666667 0.038110068 Up 0.131351311 Acp2 "acid phosphatase 2, lysosomal" K14410|1|0.0|848|mmu:11432|lysosomal acid phosphatase [EC:3.1.3.2] GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0031982//vesicle;GO:0042995//cell projection GO:0045309//protein phosphorylated amino acid binding;GO:0016791//phosphatase activity GO:0012501//programmed cell death;GO:0048731//system development;GO:0007267//cell-cell signaling;GO:0042221//response to chemical;GO:0006796//phosphate-containing compound metabolic process;GO:0007033//vacuole organization gi|29150253|ref|NP_031413.1|/0/lysosomal acid phosphatase precursor [Mus musculus] 66637 1147 8.966666667 9.19 0.035493095 Up 0.131351311 Tsen15 tRNA splicing endonuclease subunit 15 K15324|1|4e-94|347|mmu:66637|tRNA-splicing endonuclease subunit Sen15 GO:0031981//nuclear lumen - GO:0006399//tRNA metabolic process;GO:0006396//RNA processing gi|228008361|ref|NP_079953.2|/2.93818e-93/tRNA-splicing endonuclease subunit Sen15 [Mus musculus] 71008 1325 0.01 0.036666667 1.874469118 Up 0.131247884 4933401D09Rik RIKEN cDNA 4933401D09 gene - - - - "gi|148688508|gb|EDL20455.1|/7.30999e-09/mCG1033804, partial [Mus musculus]" 53876 471 0.01 0.036666667 1.874469118 Up 0.131247884 Ear3 "eosinophil-associated, ribonuclease A family, member 3" K01168|1|5e-43|174|rno:474169|pancreatic ribonuclease [EC:3.1.27.5];K10787|2|9e-40|164|rno:100361866|eosinophil cationic protein [EC:3.1.27.-] GO:0044424 "GO:0016892//endoribonuclease activity, producing 3'-phosphomonoesters;GO:0097159//organic cyclic compound binding" GO:0042221//response to chemical gi|8393283|ref|NP_059084.1|/3.79475e-74/eosinophil cationic-type ribonuclease 3 precursor [Mus musculus] 100503583 4572 0.01 0.036666667 1.874469118 Up 0.131247884 Fsbp fibrinogen silencer binding protein K10877|1|2e-130|470|ptg:102965968|DNA repair and recombination protein RAD54B [EC:3.6.4.-] GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding "GO:0006351//transcription, DNA-templated" gi|371502134|ref|NP_001243071.1|/5.01939e-150/fibrinogen silencer-binding protein [Mus musculus] 93746 1324 0.01 0.036666667 1.874469118 Up 0.131247884 Gprc5d "G protein-coupled receptor, family C, group 5, member D" K04621|1|3e-167|590|mmu:93746|G protein-coupled receptor family C group 5 member D GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0030216//keratinocyte differentiation;GO:0042303//molting cycle;GO:0007154//cell communication;GO:0030216//keratinocyte differentiation;GO:0042303//molting cycle;GO:0007154//cell communication gi|329663832|ref|NP_001192325.1|/2.65936e-166/G-protein coupled receptor family C group 5 member D isoform 1 [Mus musculus] 677296 1914 0.01 0.036666667 1.874469118 Up 0.131247884 Fcrl6 Fc receptor-like 6 K17273|1|4e-154|547|mmu:677296|Fc receptor-like protein 6 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0019902//phosphatase binding - gi|257900497|ref|NP_001158197.1|/3.00892e-153/Fc receptor-like protein 6 precursor [Mus musculus] 384701 1638 0.01 0.036666667 1.874469118 Up 0.131247884 Usp17ld ubiquitin specific peptidase 17-like D K11845|1|0.0|1070|mmu:384701|ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12] - GO:0019783//ubiquitin-like protein-specific protease activity GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process gi|112983634|ref|NP_001001559.2|/0/deubiquitinating enzyme 2a [Mus musculus] 102639566 1745 0.036666667 0.01 -1.874469118 Down 0.131247884 Ptgs2os2 "prostaglandin-endoperoxide synthase 2, opposite strand 2" - - - - - 109272 3924 0.01 0.036666667 1.874469118 Up 0.131247884 Mybpc1 "myosin binding protein C, slow-type" "K12557|1|0.0|2153|mmu:109272|myosin-binding protein C, slow-type" GO:0043232;GO:0043232 - GO:0003012//muscle system process;GO:0003012//muscle system process "gi|40254303|ref|NP_780627.2|/0/myosin-binding protein C, slow-type isoform 2 [Mus musculus]" 78073 1341 0.01 0.036666667 1.874469118 Up 0.131247884 6720468P15Rik RIKEN cDNA 6720468P15 gene - - - - - 545758 1380 0.01 0.036666667 1.874469118 Up 0.131247884 Gm5868 predicted gene 5868 "K14344|1|7e-66|246|mmu:231290|solute carrier family 10 (sodium/bile acid cotransporter), member 4" GO:0031224//intrinsic component of membrane GO:0005343//organic acid:sodium symporter activity GO:0030001//metal ion transport gi|85701520|ref|NP_001019318.1|/1.25021e-67/uncharacterized protein LOC545758 [Mus musculus] 432839 1601 0.01 0.036666667 1.874469118 Up 0.131247884 Gprin2 G protein regulated inducer of neurite outgrowth 2 - - - - gi|225690522|ref|NP_899032.2|/0/G protein-regulated inducer of neurite outgrowth 2 [Mus musculus] 22772 2967 0.036666667 0.01 -1.874469118 Down 0.131247884 Zic2 zinc finger protein of the cerebellum 2 K06235|1|0.0|699|rno:361096|zinc finger protein ZIC 2 - - - gi|325197128|ref|NP_001101862.2|/0/zinc finger protein ZIC 2 [Rattus norvegicus] 114230 1586 0.036666667 0.01 -1.874469118 Down 0.131247884 Aipl1 aryl hydrocarbon receptor-interacting protein-like 1 K17767|1|4e-176|620|mmu:114230|AH receptor-interacting protein GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding GO:0001894//tissue homeostasis;GO:0018342//protein prenylation;GO:0006915//apoptotic process;GO:0007602//phototransduction;GO:0030799 gi|568971177|ref|XP_006532060.1|/1.28709e-175/PREDICTED: aryl-hydrocarbon-interacting protein-like 1 isoform X2 [Mus musculus] 78826 2827 0.01 0.036666667 1.874469118 Up 0.131247884 P2ry10 "purinergic receptor P2Y, G-protein coupled 10" "K04274|1|0.0|641|mmu:78826|purinergic receptor P2Y, G protein-coupled, 10" GO:0031224//intrinsic component of membrane GO:0001608 GO:0035588 gi|27369579|ref|NP_766023.1|/0/putative P2Y purinoceptor 10 [Mus musculus] 66811 1592 0.036666667 0.01 -1.874469118 Down 0.131247884 Duoxa2 dual oxidase maturation factor 2 K17232|1|4e-142|507|mmu:66811|dual oxidase maturation factor 2 GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0045184//establishment of protein localization gi|13385246|ref|NP_080053.1|/3.55633e-141/dual oxidase maturation factor 2 [Mus musculus] 74667 1548 0.01 0.036666667 1.874469118 Up 0.131247884 4930434J06Rik RIKEN cDNA 4930434J06 gene - - - - - 71206 1673 0.036666667 0.01 -1.874469118 Down 0.131247884 Katnal2 katanin p60 subunit A-like 2 K07767|1|0.0|815|mmu:71206|katanin p60 ATPase-containing subunit A1 [EC:3.6.4.3] - - - - 69329 1716 0.036666667 0.01 -1.874469118 Down 0.131247884 Cfap206 cilia and flagella associated protein 206 - - - - - 433966 1715 0.01 0.036666667 1.874469118 Up 0.131247884 5730422E09Rik RIKEN cDNA 5730422E09 gene - - - - - 11298 1370 0.01 0.036666667 1.874469118 Up 0.131247884 Aanat arylalkylamine N-acetyltransferase K00669|1|6e-113|410|mmu:11298|arylalkylamine N-acetyltransferase [EC:2.3.1.87] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0008080//N-acetyltransferase activity;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0005515//protein binding GO:0009648//photoperiodism;GO:0010038//response to metal ion;GO:0006473//protein acetylation;GO:0048511//rhythmic process;GO:0043434//response to peptide hormone;GO:0051384//response to glucocorticoid;GO:0030186//melatonin metabolic process;GO:0051591//response to cAMP;GO:0034694//response to prostaglandin;GO:0009648//photoperiodism;GO:0010038//response to metal ion;GO:0006473//protein acetylation;GO:0048511//rhythmic process;GO:0043434//response to peptide hormone;GO:0051384//response to glucocorticoid;GO:0030186//melatonin metabolic process;GO:0051591//response to cAMP;GO:0034694//response to prostaglandin gi|755537084|ref|XP_011246971.1|/1.44439e-125/PREDICTED: serotonin N-acetyltransferase isoform X1 [Mus musculus] 541610 2727 0.01 0.036666667 1.874469118 Up 0.131247884 Trcg1 taste receptor cell gene 1 - - - - gi|153791210|ref|NP_001014420.2|/0/taste receptor cell protein 1 precursor [Mus musculus] 66765 1401 0.01 0.036666667 1.874469118 Up 0.131247884 4933411K16Rik RIKEN cDNA 4933411K16 gene - - - - gi|21313338|ref|NP_080028.1|/1.30244e-128/uncharacterized protein C10orf62 homolog [Mus musculus] 503845 471 0.01 0.036666667 1.874469118 Up 0.131247884 Ear12 "eosinophil-associated, ribonuclease A family, member 12" K01168|1|9e-43|174|rno:474169|pancreatic ribonuclease [EC:3.1.27.5];K10787|2|1e-38|160|rno:100361866|eosinophil cationic protein [EC:3.1.27.-] GO:0044424 "GO:0016892//endoribonuclease activity, producing 3'-phosphomonoesters;GO:0097159//organic cyclic compound binding" GO:0042221//response to chemical "gi|61097919|ref|NP_001012784.1|/6.47287e-74/eosinophil-associated, ribonuclease A family, member 12 precursor [Mus musculus]" 214766 1685 0.01 0.036666667 1.874469118 Up 0.131247884 Mmp21 matrix metallopeptidase 21 K08000|1|0.0|1147|mmu:214766|matrix metalloproteinase-21 [EC:3.4.24.-] - "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0019538//protein metabolic process gi|23308683|ref|NP_694423.1|/0/matrix metalloproteinase-21 isoform 1 precursor [Mus musculus] 105590 2751 0.01 0.036666667 1.874469118 Up 0.131247884 Zfp957 zinc finger protein 957 K19749|1|4e-28|129|lve:103083270|retinoic acid-induced protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006366//transcription from RNA polymerase II promoter gi|85701614|ref|NP_001028387.1|/0/uncharacterized protein LOC105590 [Mus musculus] 17962 1395 0.01 0.036666667 1.874469118 Up 0.131247884 Nat3 N-acetyltransferase 3 K00622|1|3e-165|583|mmu:17962|arylamine N-acetyltransferase [EC:2.3.1.5] GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0015171//amino acid transmembrane transporter activity;GO:0008080//N-acetyltransferase activity;GO:0045182//translation regulator activity GO:0006412//translation;GO:0044767//single-organism developmental process;GO:0014070//response to organic cyclic compound;GO:0006865//amino acid transport gi|148696765|gb|EDL28712.1|/0/N-acetyltransferase 3 [Mus musculus] 78465 1440 0.01 0.036666667 1.874469118 Up 0.131247884 Ccdc190 coiled-coil domain containing 190 - - - - - 22141 5941 0.036666667 0.01 -1.874469118 Down 0.131247884 Tub tubby candidate gene K19600|1|4e-118|429|cmy:102935323|tubby-related protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0004930//G-protein coupled receptor activity GO:0043010//camera-type eye development;GO:0009583//detection of light stimulus;GO:0050954//sensory perception of mechanical stimulus;GO:0006909//phagocytosis;GO:0009719;GO:0043170;GO:0007166//cell surface receptor signaling pathway gi|11230782|ref|NP_068685.1|/0/tubby protein [Mus musculus] 13490 1455 0.01 0.036666667 1.874469118 Up 0.131247884 Drd3 dopamine receptor D3 K04146|1|0.0|806|mmu:13490|dopamine receptor D3 - - - - 74426 1756 0.036666667 0.01 -1.874469118 Down 0.131247884 4933402D24Rik RIKEN cDNA 4933402D24 gene - - - - gi|371877755|ref|NP_001243087.1|/9.74449e-95/uncharacterized protein LOC74426 [Mus musculus] 231699 1715 0.01 0.036666667 1.874469118 Up 0.131247884 Oas1e 2'-5' oligoadenylate synthetase 1E K14216|1|5e-104|380|cge:100770794|2'-5'-oligoadenylate synthetase [EC:2.7.7.84] GO:0044424 GO:0032550;GO:0003723//RNA binding;GO:0030234//enzyme regulator activity;GO:0070566//adenylyltransferase activity GO:0008585//female gonad development;GO:0043086//negative regulation of catalytic activity;GO:0002252 gi|254540058|ref|NP_660211.2|/0/2'-5' oligoadenylate synthetase 1E [Mus musculus] 240239 1633 0.036666667 0.01 -1.874469118 Down 0.131247884 Gpr151 G protein-coupled receptor 151 K08435|1|0.0|766|mmu:240239|G protein-coupled receptor 151 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|33859815|ref|NP_853521.1|/0/probable G-protein coupled receptor 151 protein [Mus musculus] 252830 1336 0.01 0.036666667 1.874469118 Up 0.131247884 Obox6 oocyte specific homeobox 6 K10164|1|1e-10|70.1|chx:102178711|homeobox protein Nanog;K09337|2|7e-10|67.8|mcc:717550|cone-rod homeobox protein;K18490|4|2e-09|66.6|mze:101479009|homeobox protein OTX2 GO:0043231//intracellular membrane-bounded organelle - - gi|124517672|ref|NP_663756.2|/0/oocyte specific homeobox 6 [Mus musculus] 22164 1609 0.01 0.036666667 1.874469118 Up 0.131247884 Tnfsf4 "tumor necrosis factor (ligand) superfamily, member 4" K05469|1|2e-111|405|mmu:22164|tumor necrosis factor ligand superfamily member 4 - - - - 14622 1704 0.01 0.036666667 1.874469118 Up 0.131247884 Gjb5 "gap junction protein, beta 5" "K07624|1|2e-152|541|mmu:14622|gap junction protein, beta 5" GO:0005921//gap junction;GO:0031224//intrinsic component of membrane - GO:0060706//cell differentiation involved in embryonic placenta development;GO:0048598//embryonic morphogenesis;GO:0009888//tissue development gi|6753996|ref|NP_034421.1|/1.85651e-151/gap junction beta-5 protein [Mus musculus] 16675 1570 0.01 0.036666667 1.874469118 Up 0.131247884 Krt27 keratin 27 "K07604|1|0.0|741|mmu:16675|type I keratin, acidic" - - - - 101202684 1684 0.036666667 0.01 -1.874469118 Down 0.131247884 Uchl1os "ubiquitin carboxy-terminal hydrolase L1, opposite strand" - - - - - 11470 1513 0.01 0.036666667 1.874469118 Up 0.131247884 Actl7a actin-like 7a K05692|1|1e-91|339|cmk:103183476|actin beta/gamma 1 GO:0032991//macromolecular complex;GO:0005929//cilium;GO:0043073//germ cell nucleus;GO:0043232 - - gi|6752956|ref|NP_033741.1|/0/actin-like protein 7A [Mus musculus] 68775 1567 0.036666667 0.01 -1.874469118 Down 0.131247884 Atp6v1c2 "ATPase, H+ transporting, lysosomal V1 subunit C2" K02148|1|0.0|811|mmu:68775|V-type H+-transporting ATPase subunit C GO:0033176//proton-transporting V-type ATPase complex;GO:0033176//proton-transporting V-type ATPase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0019829//cation-transporting ATPase activity "GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient" gi|227499977|ref|NP_001153104.1|/0/V-type proton ATPase subunit C 2 isoform 1 [Mus musculus] 69195 1613 0.01 0.036666667 1.874469118 Up 0.131247884 Tmem121 transmembrane protein 121 - GO:0031224//intrinsic component of membrane - - gi|148686608|gb|EDL18555.1|/3.04438e-164/transmembrane protein 121 [Mus musculus] 76406 1613 0.01 0.036666667 1.874469118 Up 0.131247884 1700019B03Rik RIKEN cDNA 1700019B03 gene - - - - gi|568953577|ref|XP_006508984.1|/0/PREDICTED: uncharacterized protein C19orf45 homolog isoform X1 [Mus musculus] 319752 2058 0.036666667 0.01 -1.874469118 Down 0.131247884 B230209E15Rik RIKEN cDNA B230209E15 gene - - - - - 328136 3160 0.036666667 0.01 -1.874469118 Down 0.131247884 Gm805 predicted gene 805 - - - - - 78801 3093 0.01 0.036666667 1.874469118 Up 0.131247884 Ak7 adenylate kinase 7 K00939|1|0.0|1279|mmu:78801|adenylate kinase [EC:2.7.4.3] - - - gi|254675166|ref|NP_084463.1|/0/adenylate kinase 7 [Mus musculus] 74489 2295 0.04 0.013333333 -1.584962501 Down 0.131247884 5430421F17Rik RIKEN cDNA 5430421F17 gene - - - - - 14473 1812 0.036666667 0.01 -1.874469118 Down 0.131247884 Gc group specific component K12258|1|0.0|970|mmu:14473|vitamin D-binding protein GO:0043005//neuron projection;GO:0044444//cytoplasmic part;GO:0044421 GO:0008092//cytoskeletal protein binding;GO:0005496//steroid binding;GO:0005215//transporter activity GO:0044703;GO:0006066//alcohol metabolic process;GO:0043627//response to estrogen;GO:0007589//body fluid secretion;GO:0009991//response to extracellular stimulus gi|51172612|ref|NP_032122.1|/0/vitamin D-binding protein precursor [Mus musculus] 67596 1694 0.036666667 0.01 -1.874469118 Down 0.131247884 Tespa1 "thymocyte expressed, positive selection associated 1" - GO:0043234//protein complex;GO:0044424 - GO:0043623//cellular protein complex assembly;GO:0033077//T cell differentiation in thymus;GO:0050852//T cell receptor signaling pathway gi|166197692|ref|NP_899087.2|/0/protein TESPA1 [Mus musculus] 75927 1618 0.036666667 0.01 -1.874469118 Down 0.131247884 Pitpnm2os1 "phosphatidylinositol transfer protein, membrane-associated 2, opposite strand 1" - - - - - 100043665 1724 0.036666667 0.01 -1.874469118 Down 0.131247884 Gm10662 predicted gene 10662 K08798|1|6e-102|374|cge:100768554|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] - - - - 382097 1337 0.01 0.036666667 1.874469118 Up 0.131247884 Gm1123 predicted gene 1123 K06788|1|1e-87|326|ngi:103742954|coxsackievirus and adenovirus receptor GO:0031224//intrinsic component of membrane - - gi|124249111|ref|NP_001074245.1|/0/coxsackie adenovirus receptor-like precursor [Mus musculus] 104943 2684 0.01 0.036666667 1.874469118 Up 0.131247884 Fam110c "family with sequence similarity 110, member C" - GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0015631//tubulin binding GO:0016477//cell migration;GO:0030031//cell projection assembly gi|31560095|ref|NP_082104.2|/3.22928e-175/protein FAM110C [Mus musculus] 407788 1575 0.036666667 0.01 -1.874469118 Down 0.131247884 BC051142 cDNA sequence BC051142 - - - - gi|569000893|ref|XP_006524631.1|/2.52791e-127/PREDICTED: uncharacterized protein C6orf10 homolog isoform X21 [Mus musculus] 13426 2658 0.01 0.036666667 1.874469118 Up 0.131247884 Dync1i1 dynein cytoplasmic 1 intermediate chain 1 "K10415|1|0.0|1145|mmu:13426|dynein intermediate chain, cytosolic" "GO:0030286//dynein complex;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0000775//chromosome, centromeric region;GO:0030286//dynein complex;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0000775//chromosome, centromeric region;GO:0030286//dynein complex;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0000775//chromosome, centromeric region;GO:0030286//dynein complex;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0000775//chromosome, centromeric region;GO:0030286//dynein complex;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0000775//chromosome, centromeric region" GO:0015631//tubulin binding;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0003774//motor activity GO:0051234//establishment of localization;GO:0006928//movement of cell or subcellular component;GO:0051648//vesicle localization;GO:0051234//establishment of localization;GO:0006928//movement of cell or subcellular component;GO:0051648//vesicle localization;GO:0051234//establishment of localization;GO:0006928//movement of cell or subcellular component;GO:0051648//vesicle localization;GO:0051234//establishment of localization;GO:0006928//movement of cell or subcellular component;GO:0051648//vesicle localization;GO:0051234//establishment of localization;GO:0006928//movement of cell or subcellular component;GO:0051648//vesicle localization gi|300388150|ref|NP_001177955.1|/0/cytoplasmic dynein 1 intermediate chain 1 isoform 3 [Mus musculus] 232941 1631 0.01 0.036666667 1.874469118 Up 0.131247884 Ppm1n "protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)" K19790|1|0.0|680|mmu:232941|protein phosphatase 1N [EC:3.1.3.16] - GO:0046914//transition metal ion binding;GO:0016791//phosphatase activity - "gi|148691187|gb|EDL23134.1|/0/expressed sequence C79127, partial [Mus musculus]" 378425 4329 0.036666667 0.01 -1.874469118 Down 0.131247884 Nlrp12 "NLR family, pyrin domain containing 12" "K12800|1|0.0|819|oaa:100087792|NACHT, LRR and PYD domains-containing protein 3" - - - - 106557 1463 0.01 0.036666667 1.874469118 Up 0.131247884 Ldhal6b lactate dehydrogenase A-like 6B K00016|1|0.0|763|mmu:106557|L-lactate dehydrogenase [EC:1.1.1.27] GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity GO:0044710;GO:0006007//glucose catabolic process gi|30425048|ref|NP_780558.1|/0/L-lactate dehydrogenase A-like 6B [Mus musculus] 78933 1659 0.036666667 0.01 -1.874469118 Down 0.131247884 Agbl4 ATP/GTP binding protein-like 4 K05840|1|1e-68|263|myb:102243447|dopamine receptor D5;K04257|2|1e-10|70.9|shr:100920260|olfactory receptor - - - - 240817 1659 0.01 0.036666667 1.874469118 Up 0.131247884 Teddm2 transmembrane epididymal family member 2 - - - - gi|113865983|ref|NP_839974.2|/5.24827e-151/epididymal protein e9-2 [Mus musculus] 77018 6753 0.013333333 0.043333333 1.700439718 Up 0.131247884 Col25a1 "collagen, type XXV, alpha 1" "K16617|1|1e-37|162|lcm:102359040|collagen, type XIII, alpha" - - - gi|350276174|ref|NP_001231881.1|/5.18952e-176/collagen alpha-1(XXV) chain isoform 3 [Mus musculus] 66065 1365 0.01 0.036666667 1.874469118 Up 0.131247884 Hsd17b14 hydroxysteroid (17-beta) dehydrogenase 14 K00826|1|7e-87|323|ocu:100358400|branched-chain amino acid aminotransferase [EC:2.6.1.42];K08683|2|2e-26|122|crg:105349048|3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178] GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part "GO:0036094//small molecule binding;GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0008202//steroid metabolic process gi|295054257|ref|NP_079606.3|/3.77986e-141/17-beta-hydroxysteroid dehydrogenase 14 [Mus musculus] 100038577 1696 0.01 0.036666667 1.874469118 Up 0.131247884 Gm10790 predicted gene 10790 - - - - gi|74149242|dbj|BAE22407.1|/4.98787e-64/unnamed protein product [Mus musculus] 109332 3849 0.01 0.036666667 1.874469118 Up 0.131247884 Cdcp1 CUB domain containing protein 1 K06732|1|0.0|1535|mmu:109332|CUB domain-containing protein 1 GO:0031224//intrinsic component of membrane - - gi|61098143|ref|NP_598735.2|/0/CUB domain-containing protein 1 precursor [Mus musculus] 70835 1343 0.036666667 0.01 -1.874469118 Down 0.131247884 Prss22 "protease, serine 22" K09626|1|3e-176|620|mmu:70835|brain-specific serine protease 4 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|755558957|ref|XP_006524968.2|/0/PREDICTED: brain-specific serine protease 4 isoform X1 [Mus musculus] 380669 5420 0.013333333 0.04 1.584962501 Up 0.131247884 Lin28b lin-28 homolog B (C. elegans) K18754|1|4e-160|569|mmu:380669|protein lin-28 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0010586//miRNA metabolic process;GO:0006351//transcription, DNA-templated" gi|78042603|ref|NP_001026942.1|/3.19186e-159/protein lin-28 homolog B [Mus musculus] 100503468 1781 0.723333333 0.656666667 -0.139499413 Down 0.131182068 Gm14023 predicted gene 14023 K04383|1|2e-35|152|mmu:16175|interleukin 1 alpha GO:0044444//cytoplasmic part;GO:0044421 GO:0005126//cytokine receptor binding;GO:0046914//transition metal ion binding GO:0006915//apoptotic process;GO:0042094//interleukin-2 biosynthetic process;GO:0050663//cytokine secretion;GO:0019233//sensory perception of pain;GO:0043410//positive regulation of MAPK cascade;GO:0006953//acute-phase response;GO:0007254//JNK cascade;GO:0001819//positive regulation of cytokine production;GO:0010212//response to ionizing radiation;GO:0032872//regulation of stress-activated MAPK cascade;GO:0009408//response to heat;GO:0030216//keratinocyte differentiation;GO:0000302//response to reactive oxygen species;GO:0002237//response to molecule of bacterial origin;GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway;GO:0010038//response to metal ion;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0033273//response to vitamin;GO:0006694//steroid biosynthetic process;GO:0007067//mitotic nuclear division;GO:0009719 "gi|148696288|gb|EDL28235.1|/1.27576e-41/mCG146023, partial [Mus musculus]" 434377 4732 0.703333333 0.776666667 0.143086956 Up 0.131182068 Zfp560 zinc finger protein 560 K09228|1|0.0|1573|mmu:434377|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|75677614|ref|NP_001004190.2|/0/zinc finger protein 778 [Mus musculus] 66570 1217.04 0.716666667 0.79 0.140550399 Up 0.131182068 Cenpm centromere protein M K11505|1|3e-72|204|mmu:66570|centromere protein M GO:0000776//kinetochore;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0000776//kinetochore;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0000776//kinetochore;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - GO:0007067//mitotic nuclear division;GO:0007067//mitotic nuclear division;GO:0007067//mitotic nuclear division gi|13385104|ref|NP_079915.1|/5.89686e-95/centromere protein M isoform 1 [Mus musculus] 381644 5334 0.67 0.736666667 0.136850868 Up 0.131182068 Cep135 centrosomal protein 135 K16461|1|0.0|2034|mmu:381644|centrosomal protein CEP135 GO:0005813//centrosome GO:0005515//protein binding GO:0051297//centrosome organization "gi|148705959|gb|EDL37906.1|/0/centrosomal protein 135, isoform CRA_a, partial [Mus musculus]" 74008 3292 0.65 0.716666667 0.140862536 Up 0.131182068 Arsg arylsulfatase G K12381|1|0.0|1098|mmu:74008|arylsulfatase G [EC:3.1.6.-] GO:0044421;GO:0000323//lytic vacuole;GO:0044432;GO:0044421;GO:0000323//lytic vacuole GO:0008484//sulfuric ester hydrolase activity;GO:0043169//cation binding;GO:0008484//sulfuric ester hydrolase activity;GO:0043169//cation binding GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006664//glycolipid metabolic process;GO:0044237//cellular metabolic process "gi|148702415|gb|EDL34362.1|/0/arylsulfatase G, partial [Mus musculus]" 333088 4905 0.733333333 0.666666667 -0.137503524 Down 0.131182068 Kcp kielin/chordin-like protein K18273|1|1e-59|235|ola:101166587|alpha-tectorin - - - gi|568939712|ref|XP_006505194.1|/0/PREDICTED: kielin/chordin-like protein isoform X3 [Mus musculus] 268480 4163 0.693333333 0.763333333 0.13876407 Up 0.131182068 Rapgefl1 Rap guanine nucleotide exchange factor (GEF)-like 1 K04351|1|3e-110|403|myd:102765492|Rap guanine nucleotide exchange factor 4 GO:0044464 - GO:0035556//intracellular signal transduction gi|124257963|ref|NP_001074394.1|/0/rap guanine nucleotide exchange factor-like 1 [Mus musculus] 104416 3406 20.65 21.07333333 0.029276753 Up 0.131144458 Bap1 Brca1 associated protein 1 K08588|1|0.0|1311|mmu:104416|ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12] GO:0031519//PcG protein complex GO:0005488//binding;GO:0016790//thiolester hydrolase activity;GO:0019783//ubiquitin-like protein-specific protease activity GO:0007049//cell cycle;GO:0019941//modification-dependent protein catabolic process;GO:0035521 "gi|148692855|gb|EDL24802.1|/0/Brca1 associated protein 1, isoform CRA_a, partial [Mus musculus]" 70300 1715 18.14333333 18.56666667 0.033275292 Up 0.131144458 Fuz fuzzy planar cell polarity protein K12617|1|1e-46|190|bfo:BRAFLDRAFT_119484|DNA topoisomerase 2-associated protein PAT1 - - - - 16418 1495 18.37666667 18.79666667 0.032601742 Up 0.131144458 Eif6 eukaryotic translation initiation factor 6 K03264|1|7e-136|486|mmu:16418|translation initiation factor 6 - - - - 319455 3267 0.116666667 0.08 -0.544320516 Down 0.130899996 Pld5 "phospholipase D family, member 5" K16861|1|0.0|1060|mmu:319455|inactive phospholipase D5 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|880927737|ref|XP_012974586.1|/0/PREDICTED: inactive phospholipase D5 isoform X1 [Mesocricetus auratus] 16522 2668.27 0.083333333 0.12 0.526068812 Up 0.130899996 Kcnj6 "potassium inwardly-rectifying channel, subfamily J, member 6" K05000|1|0.0|818|rno:25743|potassium inwardly-rectifying channel subfamily J member 6 GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0043025//neuronal cell body;GO:0005887//integral component of plasma membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0043025//neuronal cell body;GO:0005887//integral component of plasma membrane GO:0005242//inward rectifier potassium channel activity;GO:0005488//binding;GO:0005242//inward rectifier potassium channel activity;GO:0005242//inward rectifier potassium channel activity;GO:0005242//inward rectifier potassium channel activity;GO:0005488//binding GO:0007267//cell-cell signaling;GO:0006575//cellular modified amino acid metabolic process;GO:0030001//metal ion transport;GO:0043278//response to morphine;GO:0009628//response to abiotic stimulus;GO:0034220//ion transmembrane transport;GO:0006575//cellular modified amino acid metabolic process;GO:0009628//response to abiotic stimulus;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0043278//response to morphine;GO:0006575//cellular modified amino acid metabolic process;GO:0009628//response to abiotic stimulus;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0043278//response to morphine;GO:0007267//cell-cell signaling;GO:0006575//cellular modified amino acid metabolic process;GO:0030001//metal ion transport;GO:0043278//response to morphine;GO:0009628//response to abiotic stimulus;GO:0034220//ion transmembrane transport gi|71051591|ref|NP_001020756.1|/0/G protein-activated inward rectifier potassium channel 2 isoform Girk2B [Mus musculus] 70458 1357 0.076666667 0.113333333 0.563900885 Up 0.130899996 2610318N02Rik RIKEN cDNA 2610318N02 gene K01047|1|9e-26|120|cmy:102931760|secretory phospholipase A2 [EC:3.1.1.4];K10598|2|4e-25|118|oas:101115735|peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8];K19384|4|7e-10|67.8|hmg:101237445|transmembrane protein 17 - - - gi|71274188|ref|NP_899110.2|/3.74328e-141/uncharacterized protein LOC70458 [Mus musculus] 54390 1201 0.09 0.13 0.530514717 Up 0.130899996 Sit1 suppression inducing transmembrane adaptor 1 - GO:0016021//integral component of membrane;GO:0031981//nuclear lumen GO:0019904//protein domain specific binding;GO:0019899//enzyme binding GO:0042110//T cell activation;GO:0007154//cell communication gi|227330568|ref|NP_062309.2|/2.87051e-94/signaling threshold-regulating transmembrane adapter 1 [Mus musculus] 30936 2060 0.096666667 0.14 0.534336428 Up 0.130899996 Slc46a2 "solute carrier family 46, member 2" "K14614|1|0.0|916|mmu:30936|MFS transporter, PCFT/HCP family, solute carrier family 46 (thymic stromal cotransporter), member 2" GO:0031224//intrinsic component of membrane;GO:0044464 - GO:0070229//negative regulation of lymphocyte apoptotic process;GO:0002260//lymphocyte homeostasis;GO:0030217//T cell differentiation;GO:0051234//establishment of localization gi|225543517|ref|NP_066395.3|/0/thymic stromal cotransporter protein [Mus musculus] 107934 11558 0.12 0.083333333 -0.526068812 Down 0.130899996 Celsr3 "cadherin, EGF LAG seven-pass G-type receptor 3" K04602|1|0.0|5914|mmu:107934|cadherin EGF LAG seven-pass G-type receptor 3 - - - - 231668 4054 2.75 2.876666667 0.06496644 Up 0.130768363 Vsig10 V-set and immunoglobulin domain containing 10 K18656|1|5e-21|106|cge:100759427|ATP-dependent RNA helicase DDX25 [EC:3.6.4.13];K17341|2|8e-16|89.4|cin:100186133|hemicentin - - - gi|148664203|ref|NP_001028483.2|/0/V-set and immunoglobulin domain-containing protein 10 precursor [Mus musculus] 99010 1920 3.156666667 3.286666667 0.058223221 Up 0.130768363 Lpcat4 lysophosphatidylcholine acyltransferase 4 K13512|1|0.0|947|mmu:99010|lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0046872//metal ion binding;GO:0016740//transferase activity GO:0006641//triglyceride metabolic process;GO:0046470//phosphatidylcholine metabolic process;GO:0006658//phosphatidylserine metabolic process;GO:0046473//phosphatidic acid metabolic process;GO:0046471//phosphatidylglycerol metabolic process gi|46402175|ref|NP_997089.1|/0/lysophospholipid acyltransferase LPCAT4 [Mus musculus] 104871 1975 2.986666667 3.116666667 0.061467633 Up 0.130768363 Spata7 spermatogenesis associated 7 K19655|1|3e-169|597|mmu:104871|spermatogenesis-associated protein 7 - - GO:0050953//sensory perception of light stimulus gi|575771740|ref|NP_001276502.1|/0/spermatogenesis-associated protein 7 homolog isoform 3 [Mus musculus] 11443 2151 3.253333333 3.38 0.055104599 Up 0.130768363 Chrnb1 "cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)" K04812|1|0.0|907|mmu:11443|nicotinic acetylcholine receptor beta-1 GO:0097060//synaptic membrane;GO:0005887//integral component of plasma membrane GO:0004888//transmembrane signaling receptor activity;GO:0042165//neurotransmitter binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0003012//muscle system process;GO:0006811//ion transport;GO:0006873//cellular ion homeostasis;GO:0007268//chemical synaptic transmission;GO:0055002//striated muscle cell development;GO:0030534//adult behavior gi|160358782|ref|NP_033731.3|/0/acetylcholine receptor subunit beta precursor [Mus musculus] 77065 5370 3.306666667 3.176666667 -0.057863906 Down 0.130768363 Ints7 integrator complex subunit 7 K13144|1|0.0|1761|mmu:77065|integrator complex subunit 7 "GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0043232;GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0043232;GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0043232" GO:0005488//binding GO:0010212//response to ionizing radiation;GO:0016073//snRNA metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0033554//cellular response to stress;GO:0010212//response to ionizing radiation;GO:0016073//snRNA metabolic process;GO:0033554//cellular response to stress;GO:0010212//response to ionizing radiation;GO:0016073//snRNA metabolic process "gi|148681040|gb|EDL12987.1|/0/integrator complex subunit 7, isoform CRA_d, partial [Mus musculus]" 231464 8564.1 2.993333333 2.863333333 -0.064057314 Down 0.130768363 Cnot6l "CCR4-NOT transcription complex, subunit 6-like" K12603|1|0.0|1065|mmu:231464|CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044424 GO:0043169//cation binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0043169//cation binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0043169//cation binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0043169//cation binding;GO:0000175//3'-5'-exoribonuclease activity "GO:0006396//RNA processing;GO:0050779//RNA destabilization;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0008283//cell proliferation;GO:0006396//RNA processing;GO:0050779//RNA destabilization;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0008283//cell proliferation;GO:0006396//RNA processing;GO:0050779//RNA destabilization;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0008283//cell proliferation;GO:0006396//RNA processing;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0050779//RNA destabilization;GO:0008283//cell proliferation" "gi|148688416|gb|EDL20363.1|/0/CCR4-NOT transcription complex, subunit 6-like, isoform CRA_b, partial [Mus musculus]" 624759 2832 3.05 3.18 0.060217523 Up 0.130768363 Gm20752 "predicted gene, 20752" K04676|1|6e-37|136|cge:100762264|mothers against decapentaplegic homolog 1;K00653|3|4e-12|73.2|tup:102478103|chromodomain protein Y [EC:2.3.1.48];K08798|5|6e-07|59.3|cge:103164003|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] - - - - 20403 6001 3.01 2.883333333 -0.062025855 Down 0.130768363 Itsn2 intersectin 2 K20045|1|0.0|641|mmu:20403|intersectin GO:0044424;GO:0044424;GO:0044424 GO:0046872//metal ion binding;GO:0008289//lipid binding;GO:0046872//metal ion binding;GO:0008289//lipid binding;GO:0046872//metal ion binding;GO:0008289//lipid binding GO:0007266//Rho protein signal transduction;GO:0016192//vesicle-mediated transport;GO:0007266//Rho protein signal transduction;GO:0016192//vesicle-mediated transport;GO:0007266//Rho protein signal transduction;GO:0016192//vesicle-mediated transport gi|568977611|ref|XP_006515088.1|/0/PREDICTED: intersectin-2 isoform X2 [Mus musculus] 56452 1578.35 2.756666667 2.883333333 0.064812803 Up 0.130768363 Orc6 "origin recognition complex, subunit 6" K02608|1|2e-99|266|rno:291927|origin recognition complex subunit 6 GO:0043231//intracellular membrane-bounded organelle;GO:0000808//origin recognition complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000808//origin recognition complex;GO:0000808//origin recognition complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0006260//DNA replication;GO:0006260//DNA replication;GO:0044772//mitotic cell cycle phase transition;GO:0006260//DNA replication;GO:0051320 gi|255069719|ref|NP_062690.2|/2.596e-115/origin recognition complex subunit 6 isoform a [Mus musculus] 246746 1864 1.046666667 1.13 0.110520714 Up 0.130711949 Cd300lf CD300 molecule like family member F K20395|1|2e-131|471|mmu:246746|CO300B/D/F antigen GO:0016020//membrane;GO:0031224//intrinsic component of membrane - GO:0002573//myeloid leukocyte differentiation;GO:0002573//myeloid leukocyte differentiation gi|83699402|ref|NP_663609.2|/1.6683e-132/CMRF35-like molecule 1 isoform 2 precursor [Mus musculus] 211660 4378 1.086666667 1.006666667 -0.110323415 Down 0.130711949 Cspp1 centrosome and spindle pole associated protein 1 K16771|1|0.0|1996|mmu:211660|centrosome and spindle pole-associated protein 1 GO:0005815//microtubule organizing center;GO:0005819//spindle GO:0005488//binding GO:0032467//positive regulation of cytokinesis gi|124301210|ref|NP_080769.3|/0/centrosome and spindle pole associated protein 1 [Mus musculus] 258334 981 1.033333333 1.116666667 0.11189288 Up 0.130711949 Olfr1396 olfactory receptor 1396 K04257|1|3e-179|629|mmu:258334|olfactory receptor - - - - 56368 1782 1.11 1.026666667 -0.112591826 Down 0.130711949 Cyb561d2 cytochrome b-561 domain containing 2 K08371|1|7e-91|337|mmu:56368|cytochrome b-561 domain containing protein 2 GO:0016020//membrane - - gi|625193514|ref|XP_007639286.1|/4.17855e-93/PREDICTED: cytochrome b561 domain-containing protein 2 isoform X1 [Cricetulus griseus] 11994 9071.88 0.103333333 0.146666667 0.505235308 Up 0.130655534 Pcdh15 protocadherin 15 K16500|1|0.0|3448|mmu:11994|protocadherin-15 - - - - 245684 5374 0.123333333 0.086666667 -0.509013647 Down 0.130655534 Cnksr2 connector enhancer of kinase suppressor of Ras 2 K17536|1|0.0|1792|mmu:245684|connector enhancer of kinase suppressor of Ras 2 GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0042995//cell projection;GO:0044424;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0042995//cell projection;GO:0044424 "GO:0008289//lipid binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019900//kinase binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019900//kinase binding" GO:0035556//intracellular signal transduction;GO:0006796//phosphate-containing compound metabolic process;GO:0035556//intracellular signal transduction;GO:0006796//phosphate-containing compound metabolic process gi|28972455|dbj|BAC65681.1|/0/mKIAA0902 protein [Mus musculus] 228550 1808 0.143333333 0.1 -0.519374159 Down 0.130655534 Itpka "inositol 1,4,5-trisphosphate 3-kinase A" K00911|1|0.0|780|mmu:228550|1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127] - - - gi|22122643|ref|NP_666237.1|/0/inositol-trisphosphate 3-kinase A [Mus musculus] 100502920 1230 0.086666667 0.123333333 0.509013647 Up 0.130655534 Gm16998 "predicted gene, 16998" - - - - - 12287 9693.21 0.123333333 0.086666667 -0.509013647 Down 0.130655534 Cacna1b "calcium channel, voltage-dependent, N type, alpha 1B subunit" K04849|1|0.0|4026|mmu:12287|voltage-dependent calcium channel N type alpha-1B GO:0034704//calcium channel complex;GO:0044297//cell body;GO:0030425//dendrite;GO:0033267;GO:0034704//calcium channel complex;GO:0044297//cell body;GO:0030425//dendrite;GO:0033267 GO:0005245//voltage-gated calcium channel activity;GO:0032550;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005245//voltage-gated calcium channel activity;GO:0032550;GO:0005515//protein binding;GO:0046872//metal ion binding GO:0033555//multicellular organismal response to stress;GO:0007269//neurotransmitter secretion;GO:0008015//blood circulation;GO:0044057;GO:0048545//response to steroid hormone;GO:0007600//sensory perception;GO:0097305//response to alcohol;GO:0070588//calcium ion transmembrane transport;GO:0044708//single-organism behavior;GO:0033555//multicellular organismal response to stress;GO:0007269//neurotransmitter secretion;GO:0008015//blood circulation;GO:0044057;GO:0048545//response to steroid hormone;GO:0007600//sensory perception;GO:0097305//response to alcohol;GO:0070588//calcium ion transmembrane transport;GO:0044708//single-organism behavior gi|110225366|ref|NP_031605.2|/0/voltage-dependent N-type calcium channel subunit alpha-1B isoform 2 [Mus musculus] 17687 2697 0.123333333 0.086666667 -0.509013647 Down 0.130655534 Msh5 mutS homolog 5 K08741|1|0.0|1117|mmu:17687|DNA mismatch repair protein MSH5 - - - gi|81906991|sp|Q9QUM7.1|MSH5_MOUSE/0/RecName: Full=MutS protein homolog 5 72275 522 1.79 1.89 0.078426647 Up 0.130636729 2200002D01Rik RIKEN cDNA 2200002D01 gene - - - - - 20438 2002 1.723333333 1.82 0.078736671 Up 0.130636729 Siah1b seven in absentia 1B K04506|1|9e-168|592|mmu:20438|E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27] GO:0016020//membrane;GO:0043234//protein complex;GO:0005768//endosome;GO:0016020//membrane;GO:0043234//protein complex;GO:0005768//endosome;GO:0016020//membrane;GO:0043234//protein complex;GO:0005768//endosome GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity GO:0048731//system development;GO:0070997//neuron death;GO:0031647//regulation of protein stability;GO:0097193//intrinsic apoptotic signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0006935//chemotaxis;GO:0048232//male gamete generation;GO:0048731//system development;GO:0070997//neuron death;GO:0031647//regulation of protein stability;GO:0097193//intrinsic apoptotic signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0006935//chemotaxis;GO:0048232//male gamete generation;GO:0048731//system development;GO:0070997//neuron death;GO:0031647//regulation of protein stability;GO:0097193//intrinsic apoptotic signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0006935//chemotaxis;GO:0048232//male gamete generation gi|6677949|ref|NP_033199.1|/8.64085e-167/E3 ubiquitin-protein ligase SIAH1B [Mus musculus] 104859 7793 1.77 1.673333333 -0.081024497 Down 0.130636729 Tecpr2 tectonin beta-propeller repeat containing 2 K20191|1|1e-25|122|lgi:LOTGIDRAFT_152916|Hermansky-Pudlak syndrome 5 protein - - - gi|37359890|dbj|BAC97923.1|/0/mKIAA0297 protein [Mus musculus] 70834 7094.72 16.28 16.67666667 0.034730252 Up 0.130617925 Spag9 sperm associated antigen 9 K20317|1|0.0|2341|mmu:70834|c-Jun-amino-terminal kinase-interacting protein 4 GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0051019//mitogen-activated protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0051019//mitogen-activated protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0051019//mitogen-activated protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0051019//mitogen-activated protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0051019//mitogen-activated protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0051019//mitogen-activated protein kinase binding;GO:0008092//cytoskeletal protein binding GO:0032091//negative regulation of protein binding;GO:0016192//vesicle-mediated transport;GO:0051259//protein oligomerization;GO:0042692//muscle cell differentiation;GO:0016477//cell migration;GO:0000187//activation of MAPK activity;GO:0030182//neuron differentiation;GO:0032091//negative regulation of protein binding;GO:0016192//vesicle-mediated transport;GO:0051259//protein oligomerization;GO:0042692//muscle cell differentiation;GO:0016477//cell migration;GO:0000187//activation of MAPK activity;GO:0030182//neuron differentiation;GO:0032091//negative regulation of protein binding;GO:0016192//vesicle-mediated transport;GO:0051259//protein oligomerization;GO:0042692//muscle cell differentiation;GO:0016477//cell migration;GO:0000187//activation of MAPK activity;GO:0030182//neuron differentiation;GO:0032091//negative regulation of protein binding;GO:0016192//vesicle-mediated transport;GO:0051259//protein oligomerization;GO:0042692//muscle cell differentiation;GO:0016477//cell migration;GO:0000187//activation of MAPK activity;GO:0030182//neuron differentiation;GO:0032091//negative regulation of protein binding;GO:0016192//vesicle-mediated transport;GO:0051259//protein oligomerization;GO:0042692//muscle cell differentiation;GO:0016477//cell migration;GO:0000187//activation of MAPK activity;GO:0030182//neuron differentiation;GO:0032091//negative regulation of protein binding;GO:0016192//vesicle-mediated transport;GO:0051259//protein oligomerization;GO:0042692//muscle cell differentiation;GO:0016477//cell migration;GO:0000187//activation of MAPK activity;GO:0030182//neuron differentiation gi|70887772|ref|NP_081845.2|/0/C-Jun-amino-terminal kinase-interacting protein 4 isoform 1 [Mus musculus] 23849 4217 17.18333333 16.78 -0.034267211 Down 0.130617925 Klf6 Kruppel-like factor 6 K09207|1|6e-149|531|mmu:23849|krueppel-like factor 6/7 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0043566//structure-specific DNA binding GO:0034614//cellular response to reactive oxygen species;GO:0009611//response to wounding;GO:0014070//response to organic cyclic compound;GO:0007166//cell surface receptor signaling pathway;GO:0071417//cellular response to organonitrogen compound;GO:0006366//transcription from RNA polymerase II promoter gi|84794649|ref|NP_035933.2|/5.62214e-148/Krueppel-like factor 6 [Mus musculus] 75462 1340 17.72 17.31666667 -0.033217355 Down 0.130617925 1700001C19Rik RIKEN cDNA 1700001C19 gene - - - - gi|58037411|ref|NP_083572.1|/1.3525e-111/uncharacterized protein LOC75462 isoform 1 [Mus musculus] 68292 4236 17.66333333 17.26 -0.033325162 Down 0.130617925 Stt3b "STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)" K07151|1|0.0|1561|mmu:68292|dolichyl-diphosphooligosaccharide--protein glycosyltransferase [EC:2.4.99.18] - - - - 239857 9553 0.09 0.126666667 0.493040011 Up 0.130373463 Cadm2 cell adhesion molecule 2 K06782|1|0.0|780|mmu:239857|cell adhesion molecule 2 GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0043025//neuronal cell body;GO:0044424;GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0043025//neuronal cell body;GO:0044424 - GO:0007417//central nervous system development;GO:0045216//cell-cell junction organization;GO:0022607//cellular component assembly;GO:0022610;GO:0007417//central nervous system development;GO:0045216//cell-cell junction organization;GO:0022607//cellular component assembly;GO:0022610 gi|225543375|ref|NP_848836.2|/0/cell adhesion molecule 2 isoform 1 precursor [Mus musculus] 18846 6964 0.14 0.1 -0.485426827 Down 0.130373463 Plxna3 plexin A3 K06820|1|0.0|3719|mmu:18846|plexin A GO:0044464;GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007010//cytoskeleton organization;GO:0021543//pallium development;GO:0007154//cell communication;GO:0006935//chemotaxis;GO:0021859//pyramidal neuron differentiation;GO:0030517//negative regulation of axon extension gi|124286839|ref|NP_032909.2|/0/plexin-A3 precursor [Mus musculus] 74456 1745 0.09 0.126666667 0.493040011 Up 0.130373463 4933424G05Rik RIKEN cDNA 4933424G05 gene - - - - - 243168 1730 0.126666667 0.09 -0.493040011 Down 0.130373463 Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 K15734|1|7e-66|254|crg:105330579|all-trans-retinol dehydrogenase (NAD+) [EC:1.1.1.105] - GO:0036094//small molecule binding;GO:0003824//catalytic activity;GO:0036094//small molecule binding;GO:0003824//catalytic activity GO:0044710;GO:0044710 gi|254553342|ref|NP_001156958.1|/2.13878e-167/17-beta-hydroxysteroid dehydrogenase 13 isoform 1 precursor [Mus musculus] 16150 3706.2 7.076666667 7.29 0.042848849 Up 0.130279439 Ikbkb inhibitor of kappaB kinase beta K07209|1|0.0|1451|mmu:16150|inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0005887//integral component of plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0005887//integral component of plasma membrane GO:0032550;GO:0046983//protein dimerization activity;GO:0004674//protein serine/threonine kinase activity;GO:0019900//kinase binding;GO:0032550;GO:0046983//protein dimerization activity;GO:0004674//protein serine/threonine kinase activity;GO:0019900//kinase binding GO:0006941//striated muscle contraction;GO:0042221//response to chemical;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006468//protein phosphorylation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002260//lymphocyte homeostasis;GO:0002028//regulation of sodium ion transport;GO:0006941//striated muscle contraction;GO:0042221//response to chemical;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006468//protein phosphorylation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002260//lymphocyte homeostasis;GO:0002028//regulation of sodium ion transport "gi|148700933|gb|EDL32880.1|/0/inhibitor of kappaB kinase beta, isoform CRA_a, partial [Mus musculus]" 252966 2945 7.456666667 7.243333333 -0.041877082 Down 0.130279439 Cables2 CDK5 and Abl enzyme substrate 2 K09528|1|5e-22|109|cbr:CBG04113|DnaJ homolog subfamily C member 8 - GO:0019887//protein kinase regulator activity GO:0007049//cell cycle;GO:0050794//regulation of cellular process gi|21908044|gb|AAL12171.1|/0/ik3-2 [Mus musculus] 20933 1985.4 8.013333333 8.22 0.036735904 Up 0.130279439 Med22 mediator complex subunit 22 K15139|1|2e-62|244|ngi:103742804|mediator of RNA polymerase II transcription subunit 22 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043234//protein complex "GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" GO:0006366//transcription from RNA polymerase II promoter gi|117940043|ref|NP_001071147.1|/6.34709e-80/mediator of RNA polymerase II transcription subunit 22 [Rattus norvegicus] 214663 1964 7.493333333 7.706666667 0.040499362 Up 0.130279439 Slc25a29 "solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29" "K15109|1|3e-152|541|mmu:214663|solute carrier family 25 (mitochondrial carnitine/acylcarnitine transporter), member 20/29" GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane GO:0022891//substrate-specific transmembrane transporter activity GO:0044763;GO:0051181//cofactor transport gi|31044469|ref|NP_851845.1|/2.91437e-151/mitochondrial basic amino acids transporter [Mus musculus] 233724 3619 8.646666667 8.433333333 -0.036041095 Down 0.130279439 Tmem41b transmembrane protein 41B - GO:0031224//intrinsic component of membrane - - gi|85662379|ref|NP_705745.3|/1.68365e-153/transmembrane protein 41B [Mus musculus] 27054 2799.09 8.366666667 8.16 -0.036083806 Down 0.130279439 Sec23b "SEC23 homolog B, COPII coat complex component" K14006|1|0.0|1512|mmu:27054|protein transport protein SEC23 GO:0012507//ER to Golgi transport vesicle membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0012507//ER to Golgi transport vesicle membrane GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0016482//cytosolic transport;GO:0015031//protein transport;GO:0016482//cytosolic transport;GO:0015031//protein transport;GO:0016482//cytosolic transport;GO:0015031//protein transport;GO:0016482//cytosolic transport;GO:0015031//protein transport;GO:0016482//cytosolic transport;GO:0015031//protein transport gi|31980969|ref|NP_062761.2|/0/protein transport protein Sec23B isoform 1 [Mus musculus] 68298 4527 6.793333333 6.586666667 -0.044571105 Down 0.130279439 Ncapd2 "non-SMC condensin I complex, subunit D2" K06677|1|0.0|2575|mmu:68298|condensin complex subunit 1 GO:0031981//nuclear lumen;GO:0000796//condensin complex GO:0005515//protein binding GO:0000070//mitotic sister chromatid segregation gi|37359800|dbj|BAC97878.1|/0/mKIAA0159 protein [Mus musculus] 76626 6505 21.36333333 20.97666667 -0.026351327 Down 0.130251232 Msi2 musashi RNA-binding protein 2 K14411|1|3e-179|632|mmu:76626|RNA-binding protein Musashi GO:0030529//intracellular ribonucleoprotein complex;GO:0030529//intracellular ribonucleoprotein complex GO:0008187//poly-pyrimidine tract binding;GO:0008187//poly-pyrimidine tract binding GO:0048468//cell development;GO:0048468//cell development gi|17157989|ref|NP_473384.1|/2.85733e-178/RNA-binding protein Musashi homolog 2 isoform 1 [Mus musculus] 19822 3002.41 16.53333333 16.14 -0.034737041 Down 0.130251232 Rnf4 ring finger protein 4 - GO:0016604//nuclear body;GO:0005856//cytoskeleton;GO:0016604//nuclear body;GO:0005856//cytoskeleton;GO:0016604//nuclear body;GO:0005856//cytoskeleton GO:0046914//transition metal ion binding;GO:0032183//SUMO binding;GO:0035258//steroid hormone receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0003682//chromatin binding;GO:0008134//transcription factor binding;GO:0046914//transition metal ion binding;GO:0032183//SUMO binding;GO:0035258//steroid hormone receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0003682//chromatin binding;GO:0008134//transcription factor binding;GO:0046914//transition metal ion binding;GO:0032183//SUMO binding;GO:0035258//steroid hormone receptor binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0003682//chromatin binding;GO:0008134//transcription factor binding GO:0000209//protein polyubiquitination;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0043254//regulation of protein complex assembly;GO:0000209//protein polyubiquitination;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0043254//regulation of protein complex assembly;GO:0000209//protein polyubiquitination;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0043254//regulation of protein complex assembly gi|74216801|dbj|BAE26531.1|/1.15488e-104/unnamed protein product [Mus musculus] 269800 3175.93 15.99 16.38 0.034765418 Up 0.130251232 Zfp384 zinc finger protein 384 K09228|1|2e-58|230|ecb:100629395|KRAB domain-containing zinc finger protein GO:0031981//nuclear lumen;GO:0005924//cell-substrate adherens junction GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0019904//protein domain specific binding GO:0009306//protein secretion;GO:0051169//nuclear transport;GO:0006366//transcription from RNA polymerase II promoter gi|126352391|ref|NP_780766.3|/0/zinc finger protein 384 isoform 1 [Mus musculus] 433801 3512 0.47 0.533333333 0.182376742 Up 0.130241829 Gm13212 predicted gene 13212 K09228|1|0.0|1318|mmu:102632968|KRAB domain-containing zinc finger protein - - - gi|755509826|ref|XP_011248589.1|/0/PREDICTED: uncharacterized protein LOC433801 isoform X1 [Mus musculus] 75796 8087 0.476666667 0.42 -0.182591413 Down 0.130241829 Cdyl2 "chromodomain protein, Y chromosome-like 2" K00653|1|0.0|1009|mmu:75796|chromodomain protein Y [EC:2.3.1.48] GO:0043231//intracellular membrane-bounded organelle GO:0042393//histone binding - gi|21313084|ref|NP_083717.1|/0/chromodomain Y-like protein 2 [Mus musculus] 414093 7840 0.34 0.286666667 -0.246160587 Down 0.13016661 A830082N09Rik RIKEN cDNA A830082N09 gene "K03847|1|5e-06|57.8|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - gi|148672931|gb|EDL04878.1|/3.63218e-18/mCG147136 [Mus musculus] 244585 6969 0.32 0.27 -0.245112498 Down 0.13016661 Rpgrip1l Rpgrip1-like K16550|1|0.0|2354|mmu:244585|protein fantom GO:0005815//microtubule organizing center;GO:0043296//apical junction complex GO:0031862 GO:0007186//G-protein coupled receptor signaling pathway;GO:0007507//heart development;GO:0009855//determination of bilateral symmetry;GO:0030326//embryonic limb morphogenesis;GO:0003002//regionalization;GO:0001654//eye development;GO:0007224//smoothened signaling pathway;GO:0048858//cell projection morphogenesis;GO:0022037//metencephalon development;GO:0021988//olfactory lobe development;GO:0010927 gi|145976944|ref|NP_775607.2|/0/protein fantom [Mus musculus] 232984 1748.94 2.41 2.296666667 -0.069491664 Down 0.130147805 B3gnt8 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8" "K09665|1|0.0|770|mmu:232984|beta-1,3-N-acetylglucosaminyltransferase 8 [EC:2.4.1.-]" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity GO:0006464//cellular protein modification process;GO:0006023;GO:0006464//cellular protein modification process;GO:0006023 "gi|22122729|ref|NP_666296.1|/0/UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 [Mus musculus]" 235559 5112 2.48 2.366666667 -0.067483597 Down 0.130147805 Topbp1 topoisomerase (DNA) II binding protein 1 K10728|1|0.0|2968|mmu:235559|topoisomerase (DNA) II binding protein 1 GO:0016604//nuclear body;GO:0043232;GO:0043073//germ cell nucleus GO:0003676//nucleic acid binding GO:0009314//response to radiation;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress gi|37359872|dbj|BAC97914.1|/0/mKIAA0259 protein [Mus musculus] 72569 1419 2.076666667 2.186666667 0.074463652 Up 0.130147805 Bbs5 Bardet-Biedl syndrome 5 (human) K16748|1|0.0|681|mmu:72569|Bardet-Biedl syndrome 5 protein GO:0005815//microtubule organizing center;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:1901981//phosphatidylinositol phosphate binding GO:0010927 "gi|148695091|gb|EDL27038.1|/0/Bardet-Biedl syndrome 5 (human), isoform CRA_b [Mus musculus]" 72133 4120.51 2.433333333 2.546666667 0.065676174 Up 0.130147805 Trub1 TruB pseudouridine (psi) synthase family member 1 K03177|1|5e-102|375|mmu:72133|tRNA pseudouridine55 synthase [EC:5.4.99.25] - GO:0016866//intramolecular transferase activity;GO:0003676//nucleic acid binding;GO:0016866//intramolecular transferase activity;GO:0003676//nucleic acid binding GO:0006399//tRNA metabolic process;GO:0010467//gene expression;GO:0009451//RNA modification;GO:0006399//tRNA metabolic process;GO:0010467//gene expression gi|268607501|ref|NP_084115.2|/1.99707e-108/probable tRNA pseudouridine synthase 1 isoform 2 [Mus musculus] 78611 2579 2.166666667 2.276666667 0.07144586 Up 0.130147805 Btbd19 BTB (POZ) domain containing 19 K08862|1|2e-55|219|cfr:102506528|polo-like kinase 3 [EC:2.7.11.21];K10481|2|2e-11|73.9|bmy:Bm1_21645|BTB/POZ domain-containing protein 9 - - - - 24074 3302 2.063333333 2.17 0.072718134 Up 0.130147805 Taf7 TATA-box binding protein associated factor 7 K03132|1|2e-150|536|mmu:24074|transcription initiation factor TFIID subunit 7 GO:0008023//transcription elongation factor complex;GO:0044665//MLL1/2 complex;GO:0005667//transcription factor complex GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0019899//enzyme binding;GO:0008134//transcription factor binding GO:0006366//transcription from RNA polymerase II promoter;GO:0001933//negative regulation of protein phosphorylation;GO:0006812//cation transport;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0016573//histone acetylation gi|28461141|ref|NP_786964.1|/1.73887e-149/transcription initiation factor TFIID subunit 7 [Mus musculus] 72823 8409 2.37 2.483333333 0.067390866 Up 0.130147805 Pard3b par-3 family cell polarity regulator beta K04237|1|7e-169|598|hgl:101705735|partitioning defective protein 3 - - - gi|163310767|ref|NP_001074519.2|/0/partitioning defective 3 homolog B [Mus musculus] 18015 11847 2.276666667 2.39 0.07008754 Up 0.130147805 Nf1 neurofibromatosis 1 K08052|1|0.0|5601|mmu:18015|neurofibromin 1 - - - gi|34878892|ref|NP_035027.1|/0/neurofibromin [Mus musculus] 381867 2018 2.126666667 2.02 -0.07423863 Down 0.130147805 Ovol3 ovo like zinc finger 3 K09216|1|1e-113|413|mmu:381867|ovo - - - gi|577019530|ref|NP_001276746.1|/9.49196e-113/putative transcription factor ovo-like protein 3 [Mus musculus] 22720 3955.04 2.19 2.083333333 -0.072037181 Down 0.130147805 Zfp62 zinc finger protein 62 K09228|1|0.0|959|ggo:101153126|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|67763830|ref|NP_033588.2|/0/zinc finger protein 62 isoform 1 [Mus musculus] 215474 5740.64 2.23 2.12 -0.072979445 Down 0.130147805 Sec22c "SEC22 homolog C, vesicle trafficking protein" K08520|1|2e-173|613|mmu:215474|SEC22 vesicle trafficking protein A/C GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0045184//establishment of protein localization;GO:0006810//transport;GO:0045184//establishment of protein localization;GO:0006810//transport gi|257096012|ref|NP_848792.2|/1.58414e-172/vesicle-trafficking protein SEC22c [Mus musculus] 210998 5621 2.323333333 2.216666667 -0.067804315 Down 0.130147805 Fam91a1 "family with sequence similarity 91, member A1" - - - - - 110920 4141.19 2.35 2.46 0.065997559 Up 0.130147805 Hspa13 "heat shock protein 70 family, member 13" K09491|1|0.0|872|mmu:110920|stress 70 protein chaperone microsome-associated 60kDa protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0032550 - gi|30089677|ref|NP_084477.1|/0/heat shock 70 kDa protein 13 precursor [Mus musculus] 22034 5985 2.406666667 2.52 0.066387397 Up 0.130147805 Traf6 TNF receptor-associated factor 6 K03175|1|0.0|1025|mmu:22034|TNF receptor-associated factor 6 [EC:2.3.2.27] GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0005887//integral component of plasma membrane;GO:0005635//nuclear envelope;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0005887//integral component of plasma membrane;GO:0005635//nuclear envelope;GO:0044444//cytoplasmic part GO:0019787//ubiquitin-like protein transferase activity;GO:0060089;GO:0019901//protein kinase binding;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0060089;GO:0019901//protein kinase binding;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding GO:0042090;GO:0014020;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0001894//tissue homeostasis;GO:0002833;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0002369//T cell cytokine production;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002637//regulation of immunoglobulin production;GO:0050851//antigen receptor-mediated signaling pathway;GO:0032147//activation of protein kinase activity;GO:0043406//positive regulation of MAP kinase activity;GO:0019221//cytokine-mediated signaling pathway;GO:0042476//odontogenesis;GO:0048771//tissue remodeling;GO:0001819//positive regulation of cytokine production;GO:0051403//stress-activated MAPK cascade;GO:0001773//myeloid dendritic cell activation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0065003;GO:0042098//T cell proliferation;GO:0000209//protein polyubiquitination;GO:0002478;GO:0043388//positive regulation of DNA binding;GO:0042090;GO:0014020;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0001894//tissue homeostasis;GO:0002833;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0002369//T cell cytokine production;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002637//regulation of immunoglobulin production;GO:0050851//antigen receptor-mediated signaling pathway;GO:0032147//activation of protein kinase activity;GO:0043406//positive regulation of MAP kinase activity;GO:0019221//cytokine-mediated signaling pathway;GO:0042476//odontogenesis;GO:0048771//tissue remodeling;GO:0001819//positive regulation of cytokine production;GO:0051403//stress-activated MAPK cascade;GO:0001773//myeloid dendritic cell activation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0065003;GO:0042098//T cell proliferation;GO:0000209//protein polyubiquitination;GO:0002478;GO:0043388//positive regulation of DNA binding gi|38348246|ref|NP_033450.2|/0/TNF receptor-associated factor 6 [Mus musculus] 319236 3735.99 2.306666667 2.196666667 -0.070493573 Down 0.130147805 Trim12c tripartite motif-containing 12C K10648|1|0.0|1000|mmu:319236|tripartite motif-containing protein 5 [EC:2.3.2.27] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002831;GO:0051259//protein oligomerization;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0000165//MAPK cascade;GO:0002758//innate immune response-activating signal transduction;GO:0000209//protein polyubiquitination;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002831;GO:0051259//protein oligomerization;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0000165//MAPK cascade;GO:0002758//innate immune response-activating signal transduction gi|225579155|ref|NP_783608.3|/0/tripartite motif-containing 12C [Mus musculus] 76820 4799 1.45 1.36 -0.092446249 Down 0.130129001 Fam49a "family with sequence similarity 49, member A" - GO:0044464;GO:0044464 - - "gi|148666026|gb|EDK98442.1|/0/DNA segment, Chr 12, ERATO Doi 553, expressed, isoform CRA_b, partial [Mus musculus]" 74945 629 1.42 1.513333333 0.091838867 Up 0.130129001 Acss2os "acyl-CoA synthetase short-chain family member 2, opposite strand" K01895|1|4e-15|83.2|rno:311569|acetyl-CoA synthetase [EC:6.2.1.1] GO:0044424 GO:0032550;GO:0016405//CoA-ligase activity GO:0019541//propionate metabolic process;GO:0006084//acetyl-CoA metabolic process;GO:0006083//acetate metabolic process "gi|148674181|gb|EDL06128.1|/4.14265e-41/mCG140915, partial [Mus musculus]" 229675 6727 1.386666667 1.48 0.093976148 Up 0.130129001 Rsbn1 "rosbin, round spermatid basic protein 1" K18024|1|0.0|911|phi:102108239|tyrosine-protein phosphatase non-receptor type 12/18/22 [EC:3.1.3.48] GO:0043231//intracellular membrane-bounded organelle - - gi|67906201|ref|NP_766272.2|/0/round spermatid basic protein 1 [Mus musculus] 68910 1679.27 4.343333333 4.193333333 -0.050705162 Down 0.130063184 Zfp467 zinc finger protein 467 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|146134355|ref|NP_065614.2|/0/zinc finger protein 467 isoform a [Mus musculus] 71834 4998 4.626666667 4.773333333 0.045023925 Up 0.130063184 Zbtb43 zinc finger and BTB domain containing 43 K10514|1|0.0|978|rno:311872|zinc finger and BTB domain-containing protein 43 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|71037383|ref|NP_082223.2|/0/zinc finger and BTB domain-containing protein 43 isoform a [Mus musculus] 229445 3468 4.263333333 4.416666667 0.050976095 Up 0.130063184 Ctso cathepsin O K01374|1|2e-175|619|mmu:229445|cathepsin O [EC:3.4.22.42] GO:0000323//lytic vacuole "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process gi|29244082|ref|NP_808330.1|/1.64634e-174/cathepsin O preproprotein [Mus musculus] 239667 8311.6 4.213333333 4.066666667 -0.051115316 Down 0.130063184 Dip2b disco interacting protein 2 homolog B - - - - - 74187 3425 4.433333333 4.583333333 0.048005373 Up 0.130063184 Katnb1 katanin p80 (WD40-containing) subunit B 1 K18643|1|0.0|1203|mmu:74187|katanin p80 WD40 repeat-containing subunit B1 GO:0043005//neuron projection;GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0044297//cell body;GO:0005819//spindle;GO:0005875//microtubule associated complex "GO:0046983//protein dimerization activity;GO:0015631//tubulin binding;GO:0042623//ATPase activity, coupled" GO:0010975//regulation of neuron projection development;GO:0008219//cell death;GO:0007019//microtubule depolymerization;GO:0000087//mitotic M phase gi|84095201|ref|NP_083081.2|/0/katanin p80 WD40 repeat-containing subunit B1 [Mus musculus] 75234 2532 17.56333333 17.94666667 0.03114923 Up 0.12996916 Rnf19b ring finger protein 19B K11973|1|0.0|1227|mmu:75234|E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.27] - - - gi|244790053|ref|NP_083495.1|/0/E3 ubiquitin-protein ligase RNF19B [Mus musculus] 26965 3171 20.11333333 20.49 0.026767789 Up 0.12996916 Cul1 cullin 1 K03347|1|0.0|1510|cmy:102932876|cullin 1 GO:0031981//nuclear lumen;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0044444//cytoplasmic part GO:0044389//ubiquitin-like protein ligase binding GO:0009653//anatomical structure morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0012501//programmed cell death;GO:0008283//cell proliferation;GO:0051320;GO:0051318;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0035556//intracellular signal transduction gi|537257109|gb|ERE89248.1|/0/cullin-1 [Cricetulus griseus] 56036 2442 16.55 16.92666667 0.032466677 Up 0.12996916 Ccnl2 cyclin L2 K15188|1|2e-21|107|pale:102891304|cyclin T GO:0043231//intracellular membrane-bounded organelle GO:0019900//kinase binding "GO:0006351//transcription, DNA-templated" gi|46592877|ref|NP_997561.1|/0/cyclin-L2 [Mus musculus] 100504104 642 17.71666667 18.1 0.030882506 Up 0.12996916 Gm16062 predicted gene 16062 - - - - gi|74201367|dbj|BAE26130.1|/1.10493e-52/unnamed protein product [Mus musculus] 27222 3485 0.156666667 0.113333333 -0.46712601 Down 0.129856332 Atp1a4 "ATPase, Na+/K+ transporting, alpha 4 polypeptide" K01539|1|0.0|1955|mmu:27222|sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9] GO:0005887//integral component of plasma membrane GO:0032550;GO:0008556//potassium-transporting ATPase activity;GO:0043169//cation binding "GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0030001//metal ion transport;GO:0006885//regulation of pH;GO:0009152//purine ribonucleotide biosynthetic process;GO:0048870//cell motility;GO:0048232//male gamete generation;GO:0006873//cellular ion homeostasis" gi|226958351|ref|NP_038762.1|/0/sodium/potassium-transporting ATPase subunit alpha-4 [Mus musculus] 623726 2156 0.096666667 0.133333333 0.4639471 Up 0.129856332 A430085M09Rik RIKEN cDNA A430085M09 gene K04613|1|6e-07|58.9|rno:297590|vomeronasal 2 receptor - - - - 21418 3235 0.093333333 0.13 0.478047297 Up 0.129856332 Tfap2a "transcription factor AP-2, alpha" K09176|1|0.0|758|myb:102247322|transcription factor AP-2 alpha/beta GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part "GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0042802//identical protein binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding" "GO:0043065//positive regulation of apoptotic process;GO:0030326//embryonic limb morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0014020;GO:0002064//epithelial cell development;GO:0030282//bone mineralization;GO:0021879//forebrain neuron differentiation;GO:0002072//optic cup morphogenesis involved in camera-type eye development;GO:0001656//metanephros development;GO:0050954//sensory perception of mechanical stimulus;GO:0034505//tooth mineralization;GO:0042471//ear morphogenesis;GO:0021603;GO:0072593//reactive oxygen species metabolic process;GO:0016477//cell migration;GO:0008544//epidermis development;GO:0002089//lens morphogenesis in camera-type eye;GO:0003007//heart morphogenesis;GO:0002237//response to molecule of bacterial origin;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0030198//extracellular matrix organization;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0048483//autonomic nervous system development;GO:0010171//body morphogenesis;GO:0010039//response to iron ion;GO:0003407//neural retina development;GO:0014031//mesenchymal cell development;GO:0043065//positive regulation of apoptotic process;GO:0030326//embryonic limb morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0014020;GO:0002064//epithelial cell development;GO:0030282//bone mineralization;GO:0021879//forebrain neuron differentiation;GO:0002072//optic cup morphogenesis involved in camera-type eye development;GO:0001656//metanephros development;GO:0050954//sensory perception of mechanical stimulus;GO:0034505//tooth mineralization;GO:0042471//ear morphogenesis;GO:0021603;GO:0072593//reactive oxygen species metabolic process;GO:0016477//cell migration;GO:0008544//epidermis development;GO:0002089//lens morphogenesis in camera-type eye;GO:0003007//heart morphogenesis;GO:0002237//response to molecule of bacterial origin;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0030198//extracellular matrix organization;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0048483//autonomic nervous system development;GO:0010171//body morphogenesis;GO:0010039//response to iron ion;GO:0003407//neural retina development;GO:0014031//mesenchymal cell development;GO:0043065//positive regulation of apoptotic process;GO:0030326//embryonic limb morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0014020;GO:0002064//epithelial cell development;GO:0030282//bone mineralization;GO:0021879//forebrain neuron differentiation;GO:0002072//optic cup morphogenesis involved in camera-type eye development;GO:0001656//metanephros development;GO:0050954//sensory perception of mechanical stimulus;GO:0034505//tooth mineralization;GO:0042471//ear morphogenesis;GO:0021603;GO:0072593//reactive oxygen species metabolic process;GO:0016477//cell migration;GO:0008544//epidermis development;GO:0002089//lens morphogenesis in camera-type eye;GO:0003007//heart morphogenesis;GO:0002237//response to molecule of bacterial origin;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0030198//extracellular matrix organization;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0048483//autonomic nervous system development;GO:0010171//body morphogenesis;GO:0010039//response to iron ion;GO:0003407//neural retina development;GO:0014031//mesenchymal cell development" gi|821465656|ref|XP_003760241.2|/0/PREDICTED: transcription factor AP-2-alpha isoform X1 [Sarcophilus harrisii] 72813 2825 0.156666667 0.113333333 -0.46712601 Down 0.129856332 2810454H06Rik RIKEN cDNA 2810454H06 gene - - - - - 72415 3609 0.11 0.153333333 0.479167837 Up 0.129856332 Sgol1 shugoshin-like 1 (S. pombe) K11580|1|0.0|1000|mmu:72415|shugoshin-like 1 "GO:0005815//microtubule organizing center;GO:0008278//cohesin complex;GO:0000794//condensed nuclear chromosome;GO:0000775//chromosome, centromeric region;GO:0044444//cytoplasmic part;GO:0005819//spindle" GO:0005488//binding GO:0007059//chromosome segregation;GO:0051297//centrosome organization;GO:0007067//mitotic nuclear division gi|13386294|ref|NP_082508.1|/0/shugoshin-like 1 [Mus musculus] 71099 1243 0.116666667 0.16 0.455679484 Up 0.129856332 Tssk4 testis-specific serine kinase 4 K08811|1|7e-165|582|mmu:71099|testis-specific serine kinase [EC:2.7.11.1] GO:0030141//secretory granule;GO:0030141//secretory granule;GO:0030141//secretory granule GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding GO:0048869//cellular developmental process;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006464//cellular protein modification process;GO:0048232//male gamete generation;GO:0006796//phosphate-containing compound metabolic process;GO:0048869//cellular developmental process;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006464//cellular protein modification process;GO:0048232//male gamete generation;GO:0006796//phosphate-containing compound metabolic process;GO:0048869//cellular developmental process;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006464//cellular protein modification process;GO:0048232//male gamete generation;GO:0006796//phosphate-containing compound metabolic process gi|21312834|ref|NP_081949.1|/2.18868e-177/testis-specific serine/threonine-protein kinase 4 isoform 1 [Mus musculus] 17386 2675 0.093333333 0.13 0.478047297 Up 0.129856332 Mmp13 matrix metallopeptidase 13 K07994|1|0.0|986|mmu:17386|matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-] GO:0005911//cell-cell junction;GO:0000323//lytic vacuole;GO:0005581//collagen trimer GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0070325//lipoprotein particle receptor binding GO:0001501//skeletal system development;GO:0009605//response to external stimulus;GO:0006898//receptor-mediated endocytosis;GO:0008585//female gonad development;GO:0006518//peptide metabolic process;GO:0001503//ossification;GO:0030326//embryonic limb morphogenesis;GO:0048545//response to steroid hormone;GO:0006950//response to stress;GO:0032963//collagen metabolic process;GO:0019538//protein metabolic process gi|6678896|ref|NP_032633.1|/0/collagenase 3 preproprotein [Mus musculus] 227933 3992 0.093333333 0.13 0.478047297 Up 0.129856332 Ccdc148 coiled-coil domain containing 148 - - - - gi|148694999|gb|EDL26946.1|/0/mCG50587 [Mus musculus] 237877 7272 0.156666667 0.113333333 -0.46712601 Down 0.129856332 Atad5 "ATPase family, AAA domain containing 5" K10754|1|4e-14|84.7|cel:CELE_C54G10.2|replication factor C subunit 1 GO:0043231//intracellular membrane-bounded organelle GO:0016462//pyrophosphatase activity;GO:0032550 GO:0033554//cellular response to stress gi|71143102|ref|NP_001025027.1|/0/ATPase family AAA domain-containing protein 5 [Mus musculus] 623273 1170 0.096666667 0.133333333 0.4639471 Up 0.129856332 Alms1-ps2 "Alstrom syndrome 1, pseudogene 2" K16741|1|2e-141|504|mmu:236266|alstrom syndrome protein 1 - - - gi|50510453|dbj|BAD32212.1|/5.8323e-145/mKIAA0328 protein [Mus musculus] 71213 2871 0.103333333 0.143333333 0.472068444 Up 0.129856332 Cage1 cancer antigen 1 K16308|1|1e-08|64.7|ola:101170523|citron Rho-interacting kinase [EC:2.7.11.1];K10406|2|4e-08|63.2|spu:100892079|kinesin family member C2/C3;K10352|4|4e-08|63.2|ocu:100302407|myosin heavy chain - - - gi|269995961|ref|NP_082000.2|/0/cancer-associated gene 1 protein homolog [Mus musculus] 13807 2776.33 0.733333333 0.8 0.125530882 Up 0.129790515 Eno2 "enolase 2, gamma neuronal" K01689|1|7e-116|421|mmu:13807|enolase [EC:4.2.1.11] GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043025//neuronal cell body;GO:0042995//cell projection;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0044424;GO:0016020//membrane GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0016836//hydro-lyase activity;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0016836//hydro-lyase activity GO:0044710;GO:0006007//glucose catabolic process;GO:0006007//glucose catabolic process;GO:0002164//larval development;GO:0035264//multicellular organism growth;GO:0010259//multicellular organism aging;GO:0040009//regulation of growth rate;GO:0006897//endocytosis;GO:0048806//genitalia development;GO:0009790//embryo development gi|7305027|ref|NP_038537.1|/0/gamma-enolase isoform 1 [Mus musculus] 66598 1611 0.773333333 0.846666667 0.130703692 Up 0.129790515 3110001I22Rik - - - - - gi|21313406|ref|NP_079929.1|/2.263e-151/uncharacterized protein LOC66598 [Mus musculus] 21929 4437 0.856666667 0.783333333 -0.129107603 Down 0.129790515 Tnfaip3 "tumor necrosis factor, alpha-induced protein 3" "K11859|1|0.0|1561|mmu:21929|tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]" GO:0000323//lytic vacuole;GO:0000323//lytic vacuole GO:0016790//thiolester hydrolase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0003676//nucleic acid binding;GO:0032182//ubiquitin-like protein binding;GO:0046914//transition metal ion binding;GO:0019899//enzyme binding;GO:0016790//thiolester hydrolase activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0003676//nucleic acid binding;GO:0032182//ubiquitin-like protein binding;GO:0046914//transition metal ion binding;GO:0019899//enzyme binding GO:0002467//germinal center formation;GO:0006914//autophagy;GO:0002507//tolerance induction;GO:0016579//protein deubiquitination;GO:0032611//interleukin-1 beta production;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0070425;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0050679//positive regulation of epithelial cell proliferation;GO:0009896;GO:0002313//mature B cell differentiation involved in immune response;GO:0002432//granuloma formation;GO:0002377//immunoglobulin production;GO:0008285//negative regulation of cell proliferation;GO:1901652//response to peptide;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043066//negative regulation of apoptotic process;GO:0001818//negative regulation of cytokine production;GO:0000209//protein polyubiquitination;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0022408//negative regulation of cell-cell adhesion;GO:0032496//response to lipopolysaccharide;GO:0002467//germinal center formation;GO:0006914//autophagy;GO:0002507//tolerance induction;GO:0016579//protein deubiquitination;GO:0032611//interleukin-1 beta production;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0070425;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0050679//positive regulation of epithelial cell proliferation;GO:0009896;GO:0002313//mature B cell differentiation involved in immune response;GO:0002432//granuloma formation;GO:0002377//immunoglobulin production;GO:0008285//negative regulation of cell proliferation;GO:1901652//response to peptide;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043066//negative regulation of apoptotic process;GO:0001818//negative regulation of cytokine production;GO:0000209//protein polyubiquitination;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0022408//negative regulation of cell-cell adhesion;GO:0032496//response to lipopolysaccharide gi|261862305|ref|NP_001159874.1|/0/tumor necrosis factor alpha-induced protein 3 isoform 2 [Mus musculus] 71599 3775 0.81 0.883333333 0.125036046 Up 0.129790515 Senp8 SUMO/sentrin specific peptidase 8 K08597|1|4e-126|455|mmu:71599|sentrin-specific protease 8 [EC:3.4.22.68] - GO:0019783//ubiquitin-like protein-specific protease activity;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0019783//ubiquitin-like protein-specific protease activity GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process;GO:0019538//protein metabolic process "gi|148694035|gb|EDL25982.1|/1.88116e-150/SUMO/sentrin specific peptidase 8, isoform CRA_b, partial [Mus musculus]" 319940 2474 0.136666667 0.1 -0.450661409 Down 0.129640077 Sorbs2os "sorbin and SH3 domain containing 2, opposite strand" - - - - - 102634101 1025 0.1 0.136666667 0.450661409 Up 0.129640077 Gm31763 "predicted gene, 31763" - - - - - 57342 4450 16.91333333 16.54666667 -0.031620404 Down 0.12961187 Parva "parvin, alpha" K06275|1|0.0|673|mmu:57342|parvin GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0016020//membrane GO:0008092//cytoskeletal protein binding GO:0001525//angiogenesis;GO:0016337//single organismal cell-cell adhesion;GO:0048858//cell projection morphogenesis;GO:0051259//protein oligomerization;GO:0022604//regulation of cell morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0007010//cytoskeleton organization;GO:0042221//response to chemical;GO:0014909//smooth muscle cell migration;GO:0030048//actin filament-based movement;GO:0000904//cell morphogenesis involved in differentiation gi|31982526|ref|NP_065631.3|/0/alpha-parvin [Mus musculus] 66314 3576.95 15.33666667 14.97 -0.034910734 Down 0.12961187 Tpd52l2 tumor protein D52-like 2 - GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0042802//identical protein binding;GO:0042802//identical protein binding;GO:0042802//identical protein binding;GO:0042802//identical protein binding;GO:0042802//identical protein binding;GO:0042802//identical protein binding;GO:0042802//identical protein binding;GO:0042802//identical protein binding - "gi|148675473|gb|EDL07420.1|/5.20441e-80/tumor protein D52-like 2, isoform CRA_b [Mus musculus]" 225655 2167 0.273333333 0.323333333 0.242360838 Up 0.12961187 Slmo1 slowmo homolog 1 (Drosophila) - - - - - 100502985 1966 0.273333333 0.323333333 0.242360838 Up 0.12961187 Gm10814 predicted gene 10814 K01367|1|1e-17|94.4|mmu:12333|calpain-1 [EC:3.4.22.52] GO:0016020//membrane;GO:0044424 GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004197//cysteine-type endopeptidase activity GO:0009057//macromolecule catabolic process;GO:0016485//protein processing "gi|148701245|gb|EDL33192.1|/9.4426e-17/calpain 1, isoform CRA_a [Mus musculus]" 18557 3061 16.70333333 17.07 0.031327021 Up 0.12961187 Cdk18 cyclin-dependent kinase 18 K15596|1|0.0|896|mmu:18557|cyclin-dependent kinase 18 [EC:2.7.11.22] - GO:0004674//protein serine/threonine kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|6679233|ref|NP_032821.1|/0/cyclin-dependent kinase 18 [Mus musculus] 78739 785 0.26 0.306666667 0.238159737 Up 0.12961187 9530062K07Rik RIKEN cDNA 9530062K07 gene - - - - - 629016 4641 0.306666667 0.26 -0.238159737 Down 0.12961187 Zfp953 zinc finger protein 953 K09228|1|0.0|657|mmu:629016|KRAB domain-containing zinc finger protein - - - gi|84579895|ref|NP_001033740.1|/0/zinc finger protein 953 [Mus musculus] 259279 3663 6.886666667 6.686666667 -0.042518648 Down 0.129452029 Tubgcp3 "tubulin, gamma complex associated protein 3" K16570|1|0.0|1691|mmu:259279|gamma-tubulin complex component 3 GO:0044444//cytoplasmic part;GO:0005813//centrosome;GO:0000922//spindle pole GO:0015631//tubulin binding;GO:0005198//structural molecule activity GO:0000226//microtubule cytoskeleton organization;GO:0044772//mitotic cell cycle phase transition;GO:0009566//fertilization gi|39930567|ref|NP_932148.1|/0/gamma-tubulin complex component 3 [Mus musculus] 80750 6469 7.493333333 7.296666667 -0.038370081 Down 0.129452029 N4bp1 NEDD4 binding protein 1 K18668|1|5e-45|187|bfo:BRAFLDRAFT_74489|ribonuclease ZC3H12 [EC:3.1.-.-] - - - gi|50510547|dbj|BAD32259.1|/0/mKIAA0615 protein [Mus musculus] 100316678 80 7.916666667 8.116666667 0.035994259 Up 0.129452029 Mir1902 microRNA 1902 - - - - - 226691 3496 6.27 6.466666667 0.044556804 Up 0.129452029 AI607873 expressed sequence AI607873 K12971|1|2e-42|177|mmu:26388|interferon-activable protein 202;K12966|5|4e-40|169|ecb:100057148|absent in melanoma 2 - - - gi|325995159|ref|NP_001191839.1|/0/uncharacterized protein LOC226691 [Mus musculus] 67894 2366 6.493333333 6.693333333 0.043765592 Up 0.129452029 Fam45a "family with sequence similarity 45, member A" - - - - gi|569007744|ref|XP_006527372.1|/0/PREDICTED: protein FAM45A isoform X2 [Mus musculus] 18111 1249 0.166666667 0.123333333 -0.434402824 Down 0.129433224 Nnat neuronatin - - - GO:0007417//central nervous system development;GO:0050796//regulation of insulin secretion;GO:0009746;GO:0008104//protein localization;GO:0007417//central nervous system development;GO:0050796//regulation of insulin secretion;GO:0009746;GO:0008104//protein localization "gi|148674292|gb|EDL06239.1|/1.60758e-54/neuronatin, isoform CRA_c, partial [Mus musculus]" 16995 1392 0.106666667 0.143333333 0.426264755 Up 0.129433224 Ltb4r1 leukotriene B4 receptor 1 K04296|1|1e-155|552|mmu:16995|leukotriene B4 receptor 1 GO:0031224//intrinsic component of membrane GO:0004974//leukotriene receptor activity GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway gi|568986948|ref|XP_006518729.1|/3.02862e-178/PREDICTED: leukotriene B4 receptor 1 isoform X1 [Mus musculus] 320679 934 0.11 0.146666667 0.415037499 Up 0.129433224 Samd12 sterile alpha motif domain containing 12 K00901|1|8e-06|53.5|nvi:100120935|diacylglycerol kinase (ATP) [EC:2.7.1.107] - - - gi|28893263|ref|NP_796199.1|/6.61983e-87/sterile alpha motif domain-containing protein 12 [Mus musculus] 15465 3637 0.106666667 0.143333333 0.426264755 Up 0.129433224 Hrh1 histamine receptor H1 K04149|1|0.0|954|mmu:15465|histamine receptor H1 - - - - 74071 1534 0.13 0.173333333 0.415037499 Up 0.129433224 Ifltd1 lamin tail domain containing 1 K12641|1|3e-14|82.4|tru:101077373|lamin A/C GO:0012505//endomembrane system;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0044699 gi|568944265|ref|XP_006507048.1|/0/PREDICTED: lamin tail domain-containing protein 1 isoform X1 [Mus musculus] 16975 6890.32 0.14 0.103333333 -0.438121112 Down 0.129433224 Lrp8 "low density lipoprotein receptor-related protein 8, apolipoprotein e receptor" K20052|1|0.0|1649|ecb:100060928|low-density lipoprotein receptor-related protein 8 - - - "gi|148698822|gb|EDL30769.1|/0/low density lipoprotein receptor-related protein 8, apolipoprotein e receptor [Mus musculus]" 54561 2861 0.103333333 0.14 0.438121112 Up 0.129433224 Nap1l3 nucleosome assembly protein 1-like 3 K11281|1|0.0|766|mmu:54561|nucleosome assembly protein 1-like 3 GO:0044424 - - gi|148701507|gb|EDL33454.1|/0/nucleosome assembly protein 1-like 3 [Mus musculus] 212518 3172 0.153333333 0.113333333 -0.436099115 Down 0.129433224 Sprn shadow of prion protein - - - - gi|34147163|ref|NP_898970.1|/5.35508e-23/shadow of prion protein precursor [Mus musculus] 52463 13986 0.173333333 0.13 -0.415037499 Down 0.129433224 Tet1 tet methylcytosine dioxygenase 1 K13097|1|0.0|3779|mmu:52463|methylcytosine dioxygenase [EC:1.14.11.-] - GO:0005488//binding;GO:0005488//binding GO:0009987//cellular process;GO:0009987//cellular process gi|241896976|ref|NP_081660.1|/0/methylcytosine dioxygenase TET1 isoform 2 [Mus musculus] 54672 2454 0.52 0.583333333 0.165808893 Up 0.129423822 Adgrg3 adhesion G protein-coupled receptor G3 K08452|1|0.0|1019|mmu:54672|G protein-coupled receptor 97 - - - gi|148679209|gb|EDL11156.1|/0/G protein-coupled receptor 97 [Mus musculus] 69069 1473 0.473333333 0.533333333 0.172180975 Up 0.129423822 1810011H11Rik RIKEN cDNA 1810011H11 gene - - - - "gi|148692898|gb|EDL24845.1|/6.19645e-52/mCG6353, isoform CRA_c [Mus musculus]" 78180 464 0.57 0.506666667 -0.169925001 Down 0.129423822 4930522O17Rik RIKEN cDNA 4930522O17 gene - - - - - 245695 4063 0.52 0.463333333 -0.166461146 Down 0.129423822 Tceanc transcription elongation factor A (SII) N-terminal and central domain containing K03145|1|1e-26|125|dgr:Dgri_GH10818|transcription elongation factor S-II GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0006354//DNA-templated transcription, elongation;GO:0006366//transcription from RNA polymerase II promoter" gi|145699116|ref|NP_001007578.2|/0/transcription elongation factor A N-terminal and central domain-containing protein [Mus musculus] 70951 1903 0.46 0.516666667 0.167599948 Up 0.129423822 Spata1 spermatogenesis associated 1 K12310|1|8e-24|114|mmu:74245|Di-N-acetylchitobiase [EC:3.2.1.-] - - - gi|21311949|ref|NP_081893.1|/0/spermatogenesis-associated protein 1 [Mus musculus] 29870 2707 0.486666667 0.546666667 0.167727446 Up 0.129423822 Gtse1 G two S phase expressed protein 1 K10129|1|0.0|1184|mmu:29870|G-2 and S-phase expressed protein 1 GO:0015630//microtubule cytoskeleton - - "gi|148672472|gb|EDL04419.1|/0/G two S phase expressed protein 1, isoform CRA_b, partial [Mus musculus]" 54120 1286 1.203333333 1.12 -0.103537604 Down 0.129075934 Gipc2 "GIPC PDZ domain containing family, member 2" K20056|1|3e-162|573|mmu:54120|PDZ domain-containing protein GIPC GO:0044424 - - gi|8394258|ref|NP_058563.1|/2.29851e-161/PDZ domain-containing protein GIPC2 [Mus musculus] 13865 2432 1.276666667 1.193333333 -0.097384805 Down 0.129075934 Nr2f1 "nuclear receptor subfamily 2, group F, member 1" K08547|1|0.0|712|mmu:13865|COUP transcription factor 1 GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0010975//regulation of neuron projection development;GO:0007420//brain development;GO:0016477//cell migration gi|111185902|ref|NP_034281.2|/0/COUP transcription factor 1 [Mus musculus] 11629 875 1.16 1.243333333 0.100088324 Up 0.129075934 Aif1 allograft inflammatory factor 1 K18617|1|1e-77|291|mmu:11629|allograft inflammatory factor 1 GO:0015629//actin cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044444//cytoplasmic part;GO:0043025//neuronal cell body;GO:0001726//ruffle GO:0046872//metal ion binding;GO:0003779//actin binding GO:0010467//gene expression;GO:0001932//regulation of protein phosphorylation;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0009628//response to abiotic stimulus;GO:0006809//nitric oxide biosynthetic process;GO:0030031//cell projection assembly;GO:0014911//positive regulation of smooth muscle cell migration;GO:0034341//response to interferon-gamma;GO:0072678//T cell migration;GO:0031960//response to corticosteroid;GO:0007265//Ras protein signal transduction;GO:0014912//negative regulation of smooth muscle cell migration;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0014738;GO:0042116//macrophage activation;GO:0008285//negative regulation of cell proliferation;GO:1901992//positive regulation of mitotic cell cycle phase transition;GO:0042098//T cell proliferation;GO:0009611//response to wounding;GO:0006909//phagocytosis;GO:0008154//actin polymerization or depolymerization gi|9506379|ref|NP_062340.1|/9.43447e-77/allograft inflammatory factor 1 [Mus musculus] 70325 2258 1.186666667 1.27 0.097913757 Up 0.129075934 Pigw "phosphatidylinositol glycan anchor biosynthesis, class W" "K05283|1|0.0|939|mmu:70325|phosphatidylinositol glycan, class W [EC:2.3.-.-]" GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane GO:0016740//transferase activity;GO:0016740//transferase activity GO:0006497//protein lipidation;GO:0006497//protein lipidation gi|117647259|ref|NP_081664.2|/0/phosphatidylinositol-glycan biosynthesis class W protein [Mus musculus] 106389 1773.04 1.233333333 1.153333333 -0.096753233 Down 0.129075934 Eaf2 ELL associated factor 2 K15186|1|2e-93|346|mmu:106389|ELL-associated factor GO:0008023//transcription elongation factor complex;GO:0016604//nuclear body;GO:0005654//nucleoplasm;GO:0008023//transcription elongation factor complex;GO:0016604//nuclear body - "GO:0006351//transcription, DNA-templated;GO:0012502//induction of programmed cell death;GO:0050680//negative regulation of epithelial cell proliferation;GO:0016049//cell growth;GO:0006351//transcription, DNA-templated;GO:0012502//induction of programmed cell death;GO:0050680//negative regulation of epithelial cell proliferation;GO:0016049//cell growth;GO:0006351//transcription, DNA-templated;GO:0012502//induction of programmed cell death;GO:0050680//negative regulation of epithelial cell proliferation;GO:0016049//cell growth" gi|31559524|dbj|BAC77525.1|/1.2697e-55/FESTA [Mus musculus] 243834 4316 1.073333333 1.15 0.099535674 Up 0.129075934 Zfp324 zinc finger protein 324 K09228|1|0.0|1177|mmu:243834|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - "gi|148706142|gb|EDL38089.1|/0/zinc finger protein 324, partial [Mus musculus]" 102635290 2532 0.29 0.34 0.229481846 Up 0.128897288 Ttc39aos1 Ttc39a opposite strand RNA 1 - - - - - 218311 2712 0.316666667 0.27 -0.230005605 Down 0.128897288 Zfp455 zinc finger protein 455 K09228|1|0.0|965|mmu:218311|KRAB domain-containing zinc finger protein - GO:0046872//metal ion binding "GO:0006351//transcription, DNA-templated;GO:0003006//developmental process involved in reproduction" gi|114842385|ref|NP_001041669.1|/0/zinc finger protein 455 [Mus musculus] 15182 2004 14.68333333 15.03 0.033665491 Up 0.128850276 Hdac2 histone deacetylase 2 K06067|1|0.0|858|mmu:15182|histone deacetylase 1/2 [EC:3.5.1.98] GO:0070822//Sin3-type complex;GO:0031519//PcG protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0044212//transcription regulatory region DNA binding;GO:0003682//chromatin binding;GO:0017136//NAD-dependent histone deacetylase activity GO:0030326//embryonic limb morphogenesis;GO:0006915//apoptotic process;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0044093;GO:0022603//regulation of anatomical structure morphogenesis;GO:0045687//positive regulation of glial cell differentiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0021543//pallium development;GO:0014070//response to organic cyclic compound;GO:0051726//regulation of cell cycle;GO:0001942//hair follicle development;GO:0006508//proteolysis;GO:0042476//odontogenesis;GO:0055001//muscle cell development;GO:0010975//regulation of neuron projection development;GO:0016575//histone deacetylation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0009408//response to heat;GO:0007599//hemostasis;GO:0030178//negative regulation of Wnt signaling pathway;GO:0043010//camera-type eye development;GO:0008285//negative regulation of cell proliferation;GO:0044092//negative regulation of molecular function;GO:0006366//transcription from RNA polymerase II promoter;GO:0010558;GO:0031399//regulation of protein modification process gi|171846760|gb|AAI61939.1|/0/Hdac2 protein [Rattus norvegicus] 56088 1017 17.29 17.64333333 0.029185284 Up 0.128850276 Psmg1 "proteasome (prosome, macropain) assembly chaperone 1" K11875|1|2e-161|570|mmu:56088|proteasome assembly chaperone 1 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0043623//cellular protein complex assembly gi|9506555|ref|NP_062410.1|/1.35855e-160/proteasome assembly chaperone 1 [Mus musculus] 20975 5779.88 15.67 15.31666667 -0.032902819 Down 0.128850276 Synj2 synaptojanin 2 K20279|1|0.0|2172|rno:84018|synaptojanin [EC:3.1.3.36] GO:0005874//microtubule;GO:0005741//mitochondrial outer membrane;GO:0001726//ruffle;GO:0033267;GO:0005874//microtubule;GO:0005741//mitochondrial outer membrane;GO:0001726//ruffle;GO:0033267;GO:0005874//microtubule;GO:0005741//mitochondrial outer membrane;GO:0001726//ruffle;GO:0033267;GO:0005874//microtubule;GO:0005741//mitochondrial outer membrane;GO:0001726//ruffle;GO:0033267;GO:0005874//microtubule;GO:0005741//mitochondrial outer membrane;GO:0001726//ruffle;GO:0033267 GO:0046030//inositol trisphosphate phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0036094//small molecule binding;GO:0046030//inositol trisphosphate phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0036094//small molecule binding;GO:0046030//inositol trisphosphate phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0036094//small molecule binding;GO:0046030//inositol trisphosphate phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0036094//small molecule binding;GO:0046030//inositol trisphosphate phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0036094//small molecule binding GO:0007417//central nervous system development;GO:0048311//mitochondrion distribution;GO:0046488//phosphatidylinositol metabolic process;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0007417//central nervous system development;GO:0048311//mitochondrion distribution;GO:0046488//phosphatidylinositol metabolic process;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0007417//central nervous system development;GO:0048311//mitochondrion distribution;GO:0046488//phosphatidylinositol metabolic process;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0007417//central nervous system development;GO:0048311//mitochondrion distribution;GO:0046488//phosphatidylinositol metabolic process;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0007417//central nervous system development;GO:0048311//mitochondrion distribution;GO:0046488//phosphatidylinositol metabolic process;GO:0046838//phosphorylated carbohydrate dephosphorylation gi|568997951|ref|XP_006523268.1|/0/PREDICTED: synaptojanin-2 isoform X4 [Mus musculus] 67812 4093 15.14666667 14.79666667 -0.033728126 Down 0.128850276 Ubxn4 UBX domain protein 4 - GO:0012505//endomembrane system;GO:0016020//membrane;GO:0031981//nuclear lumen GO:0005488//binding GO:0035966//response to topologically incorrect protein gi|85861252|ref|NP_080666.2|/0/UBX domain-containing protein 4 [Mus musculus] 68556 1811 19.22333333 18.87 -0.026764099 Down 0.128850276 Uckl1 uridine-cytidine kinase 1-like 1 K00876|1|0.0|1029|mmu:68556|uridine kinase [EC:2.7.1.48] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0019206//nucleoside kinase activity GO:0006222//UMP biosynthetic process;GO:0006241//CTP biosynthetic process gi|31541796|ref|NP_081041.2|/0/uridine-cytidine kinase-like 1 [Mus musculus] 57837 2055 15.44 15.79 0.032338419 Up 0.128850276 Eral1 Era (G-protein)-like 1 (E. coli) - GO:0019866//organelle inner membrane;GO:0044429 GO:0032550;GO:0003723//RNA binding;GO:0043021//ribonucleoprotein complex binding GO:0022618//ribonucleoprotein complex assembly "gi|165377197|ref|NP_071708.2|/0/GTPase Era, mitochondrial [Mus musculus]" 67422 3110 14.69 14.34333333 -0.034454056 Down 0.128850276 Dhdds dehydrodolichyl diphosphate synthase "K11778|1|0.0|654|mmu:67422|ditrans,polycis-polyprenyl diphosphate synthase [EC:2.5.1.87]" GO:0043231//intracellular membrane-bounded organelle GO:0016740//transferase activity - "gi|148698093|gb|EDL30040.1|/0/dehydrodolichyl diphosphate synthase, isoform CRA_a, partial [Mus musculus]" 208449 3418.17 19.50666667 19.85666667 0.02565619 Up 0.128850276 Sgms1 sphingomyelin synthase 1 K04714|1|0.0|867|mmu:208449|shingomyelin synthase [EC:2.7.8.27] GO:0031228//intrinsic component of Golgi membrane;GO:0031985//Golgi cisterna;GO:0031228//intrinsic component of Golgi membrane;GO:0031985//Golgi cisterna;GO:0031228//intrinsic component of Golgi membrane;GO:0031985//Golgi cisterna "GO:0016780//phosphotransferase activity, for other substituted phosphate groups;GO:0016780//phosphotransferase activity, for other substituted phosphate groups;GO:0016780//phosphotransferase activity, for other substituted phosphate groups" GO:0032496//response to lipopolysaccharide;GO:0010467//gene expression;GO:0040007//growth;GO:0006915//apoptotic process;GO:0034612//response to tumor necrosis factor;GO:0006684//sphingomyelin metabolic process;GO:0006952//defense response;GO:0032496//response to lipopolysaccharide;GO:0010467//gene expression;GO:0040007//growth;GO:0006915//apoptotic process;GO:0034612//response to tumor necrosis factor;GO:0006684//sphingomyelin metabolic process;GO:0006952//defense response;GO:0032496//response to lipopolysaccharide;GO:0010467//gene expression;GO:0040007//growth;GO:0006915//apoptotic process;GO:0034612//response to tumor necrosis factor;GO:0006684//sphingomyelin metabolic process;GO:0006952//defense response gi|55741833|ref|NP_659041.3|/0/phosphatidylcholine:ceramide cholinephosphotransferase 1 [Mus musculus] 320165 6789.31 14.37666667 14.72666667 0.034701703 Up 0.128850276 Tacc1 "transforming, acidic coiled-coil containing protein 1" K14281|1|3e-171|606|mmu:320165|transforming acidic coiled-coil-containing protein 1 GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0005515//protein binding;GO:0005515//protein binding GO:0007017//microtubule-based process;GO:0021543//pallium development;GO:0021846//cell proliferation in forebrain;GO:0007010//cytoskeleton organization;GO:0007017//microtubule-based process;GO:0021543//pallium development;GO:0021846//cell proliferation in forebrain gi|40556391|ref|NP_955355.1|/0/transforming acidic coiled-coil-containing protein 1 short isoform [Mus musculus] 14376 3937.25 18.51333333 18.86 0.026765 Up 0.128850276 Ganab alpha glucosidase 2 alpha neutral subunit "K05546|1|0.0|1869|mmu:14376|alpha 1,3-glucosidase [EC:3.2.1.84]" GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle "GO:0005488//binding;GO:0004558//alpha-1,4-glucosidase activity;GO:0005488//binding;GO:0004558//alpha-1,4-glucosidase activity" GO:0006487//protein N-linked glycosylation;GO:0006487//protein N-linked glycosylation "gi|148701451|gb|EDL33398.1|/0/alpha glucosidase 2 alpha neutral subunit, isoform CRA_a, partial [Mus musculus]" 76563 1970 17.1 17.45 0.029230711 Up 0.128850276 Qrsl1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 K02433|1|0.0|1016|mmu:76563|aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] - - - - 209354 2012 14.85666667 15.21 0.033909693 Up 0.128850276 Eif2b1 "eukaryotic translation initiation factor 2B, subunit 1 (alpha)" K03239|1|1e-151|539|mmu:209354|translation initiation factor eIF-2B subunit alpha - - - - 20842 6010 2.726666667 2.843333333 0.060444898 Up 0.128615217 Stag1 stromal antigen 1 K06671|1|0.0|2302|mmu:20842|cohesin complex subunit SA-1/2 GO:0043231//intracellular membrane-bounded organelle;GO:0043232 - GO:0000087//mitotic M phase gi|507946583|ref|XP_004682233.1|/0/PREDICTED: cohesin subunit SA-1 isoform X1 [Condylura cristata] 66371 1790 3.106666667 2.986666667 -0.056831223 Down 0.128615217 Chmp4c charged multivesicular body protein 4C K12194|1|2e-83|312|mmu:66371|charged multivesicular body protein 4 GO:0005768//endosome - GO:0051234//establishment of localization gi|148673213|gb|EDL05160.1|/1.00127e-94/RIKEN cDNA 2310010I16 [Mus musculus] 68511 1434 2.683333333 2.806666667 0.06483145 Up 0.128615217 Dcdc2c doublecortin domain containing 2C - - - GO:0007165//signal transduction gi|322510020|sp|Q9D1B8.2|DCD2C_MOUSE/9.13376e-103/RecName: Full=Doublecortin domain-containing protein 2C 70832 2068 2.836666667 2.96 0.061400545 Up 0.128615217 4921504A21Rik RIKEN cDNA 4921504A21 gene K17780|1|5e-25|85.9|ocu:100346423|mitochondrial import inner membrane translocase subunit TIM8 GO:0019866//organelle inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0019866//organelle inner membrane;GO:0005758//mitochondrial intermembrane space GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0050954//sensory perception of mechanical stimulus;GO:0006605//protein targeting;GO:0019538//protein metabolic process;GO:0050954//sensory perception of mechanical stimulus;GO:0006605//protein targeting;GO:0019538//protein metabolic process gi|672017954|ref|XP_008773878.1|/2.94447e-39/PREDICTED: uncharacterized protein LOC102547160 [Rattus norvegicus] 268930 2039 3.023333333 2.906666667 -0.056774416 Down 0.128615217 Pkmyt1 "protein kinase, membrane associated tyrosine/threonine 1" K06633|1|0.0|983|mmu:268930|membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity GO:0044763;GO:0006464//cellular protein modification process;GO:0010921//regulation of phosphatase activity "gi|148690317|gb|EDL22264.1|/0/protein kinase, membrane associated tyrosine/threonine 1, isoform CRA_a, partial [Mus musculus]" 230936 3128 2.956666667 2.84 -0.058080674 Down 0.128615217 Phf13 PHD finger protein 13 "K06158|1|5e-27|126|fch:102049818|ATP-binding cassette, subfamily F, member 3;K09189|3|3e-06|57.4|hst:105191765|histone-lysine N-methyltransferase MLL5 [EC:2.1.1.43]" GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0042393//histone binding GO:0006325//chromatin organization;GO:0000070//mitotic sister chromatid segregation gi|164565405|ref|NP_766293.2|/9.56988e-150/PHD finger protein 13 [Mus musculus] 234686 3951 7.346666667 7.16 -0.037130231 Down 0.128568205 Fhod1 formin homology 2 domain containing 1 K02184|1|1e-21|108|phu:Phum_PHUM602670|formin 2;K05741|2|6e-21|106|mde:105261990|diaphanous 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043232 - GO:0032233//positive regulation of actin filament bundle assembly;GO:0006366//transcription from RNA polymerase II promoter gi|269973931|ref|NP_808367.2|/0/FH1/FH2 domain-containing protein 1 [Mus musculus] 15468 2072.46 6.743333333 6.55 -0.041967007 Down 0.128568205 Prmt2 protein arginine N-methyltransferase 2 K11435|1|0.0|450|mmu:15468|type I protein arginine methyltransferase [EC:2.1.1.319] - - - - 69792 1019 6.423333333 6.233333333 -0.043318302 Down 0.128568205 Med6 mediator complex subunit 6 K15128|1|1e-129|464|cge:100762349|mediator of RNA polymerase II transcription subunit 6 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter gi|158564080|sp|Q921D4.2|MED6_MOUSE/3.28037e-130/RecName: Full=Mediator of RNA polymerase II transcription subunit 6; AltName: Full=Mediator complex subunit 6 56876 2943 7.156666667 7.35 0.038456465 Up 0.128568205 Nsmf NMDA receptor synaptonuclear signaling and neuronal migration factor - - - - - 320174 2305 0.346666667 0.296666667 -0.224706287 Down 0.128502388 A830082K12Rik RIKEN cDNA A830082K12 gene K08547|1|3e-24|116|ptg:102957955|COUP transcription factor 1;K08548|3|3e-16|89.7|lcm:102366416|COUP transcription factor 2 - - - - 109676 5949.25 14.5 14.16333333 -0.033892057 Down 0.12838956 Ank2 "ankyrin 2, brain" K10380|1|0.0|6115|cge:100757830|ankyrin GO:0044291//cell-cell contact zone;GO:0097060//synaptic membrane;GO:0016021//integral component of membrane;GO:0031672//A band;GO:0031674//I band;GO:0042383//sarcolemma;GO:0044459 GO:0008092//cytoskeletal protein binding;GO:0016247//channel regulator activity;GO:0019900//kinase binding GO:0002027//regulation of heart rate;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0031647//regulation of protein stability;GO:0007009//plasma membrane organization;GO:0006612//protein targeting to membrane;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0006915//apoptotic process;GO:0003230//cardiac atrium development;GO:0060306//regulation of membrane repolarization;GO:0086065//cell communication involved in cardiac conduction;GO:0019722//calcium-mediated signaling;GO:0006813//potassium ion transport;GO:0033365//protein localization to organelle gi|568921592|ref|XP_006500968.1|/0/PREDICTED: ankyrin-2 isoform X34 [Mus musculus] 22687 2984 15.05 14.71 -0.03296624 Down 0.12838956 Zpr1 ZPR1 zinc finger K06874|1|0.0|842|mmu:22687|zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - gi|6756053|ref|NP_035882.1|/0/zinc finger protein ZPR1 [Mus musculus] 70153 2822 15.55666667 15.9 0.031493799 Up 0.12838956 2210016F16Rik RIKEN cDNA 2210016F16 gene - - - - gi|254675232|ref|NP_081611.1|/3.54895e-172/UPF0553 protein C9orf64 homolog [Mus musculus] 67465 4916 16.76333333 17.1 0.028687272 Up 0.12838956 Sf3a1 "splicing factor 3a, subunit 1" K12825|1|0.0|1134|mmu:67465|splicing factor 3A subunit 1 GO:0005681//spliceosomal complex GO:0003676//nucleic acid binding GO:0000377 gi|165932270|ref|NP_080451.4|/0/splicing factor 3A subunit 1 [Mus musculus] 74343 2647 17.24333333 17.58 0.02789638 Up 0.12838956 Crtc2 CREB regulated transcription coactivator 2 K16333|1|0.0|1016|mmu:74343|CREB-regulated transcription coactivator 2 GO:0031981//nuclear lumen - GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006006//glucose metabolic process;GO:0033500//carbohydrate homeostasis gi|58037361|ref|NP_083157.1|/0/CREB-regulated transcription coactivator 2 [Mus musculus] 19016 1977.67 15.72333333 15.38666667 -0.031226377 Down 0.12838956 Pparg peroxisome proliferator activated receptor gamma K08530|1|0.0|987|mmu:19016|peroxisome proliferator-activated receptor gamma GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0042974//retinoic acid receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0003713//transcription coactivator activity;GO:0038023//signaling receptor activity;GO:0050542;GO:0046914//transition metal ion binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0042974//retinoic acid receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0003713//transcription coactivator activity;GO:0038023//signaling receptor activity;GO:0050542;GO:0046914//transition metal ion binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0042974//retinoic acid receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0003713//transcription coactivator activity;GO:0038023//signaling receptor activity;GO:0050542;GO:0046914//transition metal ion binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0042974//retinoic acid receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0003713//transcription coactivator activity;GO:0038023//signaling receptor activity;GO:0050542;GO:0046914//transition metal ion binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding" GO:0021700//developmental maturation;GO:0019395//fatty acid oxidation;GO:0032868//response to insulin;GO:0006915//apoptotic process;GO:0044093;GO:0045687//positive regulation of glial cell differentiation;GO:0015031//protein transport;GO:0016049//cell growth;GO:0010742//macrophage derived foam cell differentiation;GO:0055094//response to lipoprotein particle;GO:0032799//low-density lipoprotein receptor particle metabolic process;GO:0012502//induction of programmed cell death;GO:0045444//fat cell differentiation;GO:0002526//acute inflammatory response;GO:0010226//response to lithium ion;GO:0033500//carbohydrate homeostasis;GO:0010878//cholesterol storage;GO:0030522//intracellular receptor signaling pathway;GO:0051348//negative regulation of transferase activity;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0048545//response to steroid hormone;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0033273//response to vitamin;GO:0008015//blood circulation;GO:0002573//myeloid leukocyte differentiation;GO:0010558;GO:0014074//response to purine-containing compound;GO:0010888//negative regulation of lipid storage;GO:0009887//organ morphogenesis;GO:0015908//fatty acid transport;GO:0001816//cytokine production;GO:0021700//developmental maturation;GO:0019395//fatty acid oxidation;GO:0032868//response to insulin;GO:0006915//apoptotic process;GO:0044093;GO:0045687//positive regulation of glial cell differentiation;GO:0015031//protein transport;GO:0016049//cell growth;GO:0010742//macrophage derived foam cell differentiation;GO:0055094//response to lipoprotein particle;GO:0032799//low-density lipoprotein receptor particle metabolic process;GO:0012502//induction of programmed cell death;GO:0045444//fat cell differentiation;GO:0002526//acute inflammatory response;GO:0010226//response to lithium ion;GO:0033500//carbohydrate homeostasis;GO:0010878//cholesterol storage;GO:0030522//intracellular receptor signaling pathway;GO:0051348//negative regulation of transferase activity;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0048545//response to steroid hormone;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0033273//response to vitamin;GO:0008015//blood circulation;GO:0002573//myeloid leukocyte differentiation;GO:0010558;GO:0014074//response to purine-containing compound;GO:0010888//negative regulation of lipid storage;GO:0009887//organ morphogenesis;GO:0015908//fatty acid transport;GO:0001816//cytokine production;GO:0021700//developmental maturation;GO:0019395//fatty acid oxidation;GO:0032868//response to insulin;GO:0006915//apoptotic process;GO:0044093;GO:0045687//positive regulation of glial cell differentiation;GO:0015031//protein transport;GO:0016049//cell growth;GO:0010742//macrophage derived foam cell differentiation;GO:0055094//response to lipoprotein particle;GO:0032799//low-density lipoprotein receptor particle metabolic process;GO:0012502//induction of programmed cell death;GO:0045444//fat cell differentiation;GO:0002526//acute inflammatory response;GO:0010226//response to lithium ion;GO:0033500//carbohydrate homeostasis;GO:0010878//cholesterol storage;GO:0030522//intracellular receptor signaling pathway;GO:0051348//negative regulation of transferase activity;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0048545//response to steroid hormone;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0033273//response to vitamin;GO:0008015//blood circulation;GO:0002573//myeloid leukocyte differentiation;GO:0010558;GO:0014074//response to purine-containing compound;GO:0010888//negative regulation of lipid storage;GO:0009887//organ morphogenesis;GO:0015908//fatty acid transport;GO:0001816//cytokine production;GO:0021700//developmental maturation;GO:0019395//fatty acid oxidation;GO:0032868//response to insulin;GO:0006915//apoptotic process;GO:0044093;GO:0045687//positive regulation of glial cell differentiation;GO:0015031//protein transport;GO:0016049//cell growth;GO:0010742//macrophage derived foam cell differentiation;GO:0055094//response to lipoprotein particle;GO:0032799//low-density lipoprotein receptor particle metabolic process;GO:0012502//induction of programmed cell death;GO:0045444//fat cell differentiation;GO:0002526//acute inflammatory response;GO:0010226//response to lithium ion;GO:0033500//carbohydrate homeostasis;GO:0010878//cholesterol storage;GO:0030522//intracellular receptor signaling pathway;GO:0051348//negative regulation of transferase activity;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0048545//response to steroid hormone;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0033273//response to vitamin;GO:0008015//blood circulation;GO:0002573//myeloid leukocyte differentiation;GO:0010558;GO:0014074//response to purine-containing compound;GO:0010888//negative regulation of lipid storage;GO:0009887//organ morphogenesis;GO:0015908//fatty acid transport;GO:0001816//cytokine production gi|187960103|ref|NP_035276.2|/0/peroxisome proliferator-activated receptor gamma isoform 2 [Mus musculus] 238673 3490 4.22 4.08 -0.048673847 Down 0.128210914 Zfp367 zinc finger protein 367 K09229|1|5e-17|93.2|ocu:100352727|KRAB and SCAN domains-containing zinc finger protein GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006366//transcription from RNA polymerase II promoter gi|30425244|ref|NP_780703.1|/1.67108e-150/zinc finger protein 367 [Mus musculus] 20502 4180 4.163333333 4.3 0.046597589 Up 0.128210914 Slc16a2 "solute carrier family 16 (monocarboxylic acid transporters), member 2" "K08231|1|0.0|862|mmu:20502|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 2" GO:0016021//integral component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0046943//carboxylic acid transmembrane transporter activity GO:0044763;GO:0009914//hormone transport;GO:0046942//carboxylic acid transport gi|112421075|ref|NP_033223.2|/0/monocarboxylate transporter 8 [Mus musculus] 78334 5798.89 4.26 4.12 -0.048209093 Down 0.128210914 Cdk19 cyclin-dependent kinase 19 K02208|1|0.0|730|pps:100977722|cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23] - GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0032550 GO:0044763;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0044763;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0044763;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0044763;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|28972574|dbj|BAC65703.1|/0/mKIAA1028 protein [Mus musculus] 54342 2536 3.886666667 3.75 -0.051642787 Down 0.128210914 Gnpnat1 glucosamine-phosphate N-acetyltransferase 1 K00621|1|4e-90|335|mmu:54342|glucosamine-phosphate N-acetyltransferase [EC:2.3.1.4] GO:0005768//endosome;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0008080//N-acetyltransferase activity;GO:0030246//carbohydrate binding GO:1901071;GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0044767//single-organism developmental process;GO:0006487//protein N-linked glycosylation gi|9506761|ref|NP_062298.1|/3.3195e-89/glucosamine 6-phosphate N-acetyltransferase [Mus musculus] 17129 6585 4.03 4.166666667 0.04811385 Up 0.128210914 Smad5 SMAD family member 5 K16790|1|0.0|779|mmu:17129|mothers against decapentaplegic homolog 5 GO:0031981//nuclear lumen;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0044389//ubiquitin-like protein ligase binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005072//transforming growth factor beta receptor, cytoplasmic mediator activity;GO:0043169//cation binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005072//transforming growth factor beta receptor, cytoplasmic mediator activity;GO:0043169//cation binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005072//transforming growth factor beta receptor, cytoplasmic mediator activity;GO:0043169//cation binding" GO:0001501//skeletal system development;GO:0071363//cellular response to growth factor stimulus;GO:0006941//striated muscle contraction;GO:0001649//osteoblast differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0003006//developmental process involved in reproduction;GO:0014070//response to organic cyclic compound;GO:0009790//embryo development;GO:0030099//myeloid cell differentiation;GO:0006464//cellular protein modification process;GO:0035295//tube development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0001501//skeletal system development;GO:0071363//cellular response to growth factor stimulus;GO:0006941//striated muscle contraction;GO:0001649//osteoblast differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0003006//developmental process involved in reproduction;GO:0014070//response to organic cyclic compound;GO:0009790//embryo development;GO:0030099//myeloid cell differentiation;GO:0006464//cellular protein modification process;GO:0035295//tube development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0001501//skeletal system development;GO:0071363//cellular response to growth factor stimulus;GO:0006941//striated muscle contraction;GO:0001649//osteoblast differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0003006//developmental process involved in reproduction;GO:0014070//response to organic cyclic compound;GO:0009790//embryo development;GO:0030099//myeloid cell differentiation;GO:0006464//cellular protein modification process;GO:0035295//tube development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048646//anatomical structure formation involved in morphogenesis gi|1763543|gb|AAB39737.1|/0/Smad5 [Mus musculus] 218210 6021 4.376666667 4.24 -0.045768246 Down 0.128210914 Nup153 nucleoporin 153 K14296|1|0.0|2399|mmu:218210|nuclear pore complex protein Nup153 - - - - 72162 4975 3.77 3.91 0.052604084 Up 0.128210914 Dhx36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 K14442|1|0.0|1922|mmu:72162|ATP-dependent RNA helicase DHX36 [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle "GO:0003723//RNA binding;GO:0042623//ATPase activity, coupled;GO:0032550" GO:0051707//response to other organism;GO:0043331//response to dsRNA gi|240848573|ref|NP_082412.2|/0/ATP-dependent RNA helicase DHX36 [Mus musculus] 11727 816 4.023333333 4.166666667 0.050502419 Up 0.128210914 Ang "angiogenin, ribonuclease, RNase A family, 5" K16631|1|6e-70|266|mmu:11727|angiogenin [EC:3.1.27.-] - - - - 170749 5710 4.31 4.453333333 0.047197733 Up 0.128210914 Mtmr4 myotubularin related protein 4 K18082|1|0.0|2424|mmu:170749|myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95] GO:0005769//early endosome GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity GO:0006470//protein dephosphorylation;GO:0046474//glycerophospholipid biosynthetic process;GO:0007179//transforming growth factor beta receptor signaling pathway gi|18875368|ref|NP_573478.1|/0/myotubularin-related protein 4 [Mus musculus] 213582 6218 0.183333333 0.14 -0.389042291 Down 0.128201512 Map9 microtubule-associated protein 9 K10434|1|0.0|949|mmu:213582|microtubule-associated protein 9 - - - gi|124486997|ref|NP_001074699.1|/0/microtubule-associated protein 9 [Mus musculus] 242248 2869 0.113333333 0.15 0.404390255 Up 0.128201512 Bank1 B cell scaffold protein with ankyrin repeats 1 K12230|1|3e-17|93.6|lcm:102346297|phosphoinositide 3-kinase adapter protein 1 - GO:0019900//kinase binding;GO:0019900//kinase binding GO:0006875//cellular metal ion homeostasis;GO:0046649//lymphocyte activation;GO:0006875//cellular metal ion homeostasis;GO:0046649//lymphocyte activation gi|28628260|gb|AAO13613.1|/0/AVIEF [Mus musculus] 213522 3019 0.116666667 0.153333333 0.394278939 Up 0.128201512 Plekhg6 "pleckstrin homology domain containing, family G (with RhoGef domain) member 6" K19464|1|3e-116|422|mgp:100547291|pleckstrin homology domain-containing family G member 5 - - - "gi|148667413|gb|EDK99829.1|/0/pleckstrin homology domain containing, family G (with RhoGef domain) member 6, isoform CRA_a [Mus musculus]" 623781 3067 0.113333333 0.15 0.404390255 Up 0.128201512 Gm14137 predicted gene 14137 - GO:0043231//intracellular membrane-bounded organelle - - "gi|85986613|ref|NP_001034312.1|/1.78892e-100/uncharacterized protein C15orf62 homolog, mitochondrial [Mus musculus]" 71803 1367 0.183333333 0.14 -0.389042291 Down 0.128201512 Slc25a18 "solute carrier family 25 (mitochondrial carrier), member 18" "K15107|1|7e-180|632|mmu:71803|solute carrier family 25 (mitochondrial glutamate transporter), member 18/22" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0051234//establishment of localization;GO:0044763 gi|124486670|ref|NP_001074517.1|/5.96507e-179/mitochondrial glutamate carrier 2 [Mus musculus] 70385 2526 0.136666667 0.18 0.397335498 Up 0.128201512 Spdl1 spindle apparatus coiled-coil protein 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005819//spindle;GO:0000777//condensed chromosome kinetochore GO:0005488//binding GO:0000070//mitotic sister chromatid segregation;GO:0040001//establishment of mitotic spindle localization;GO:0034502//protein localization to chromosome gi|13879388|gb|AAH06674.1|/0/Coiled-coil domain containing 99 [Mus musculus] 12190 10940 0.133333333 0.176666667 0.40599236 Up 0.128201512 Brca2 "breast cancer 2, early onset" K08775|1|0.0|6329|mmu:12190|breast cancer 2 susceptibility protein - - - "gi|148673933|gb|EDL05880.1|/0/breast cancer 2, partial [Mus musculus]" 210710 2129 0.89 0.82 -0.118181426 Down 0.1281545 Gab3 growth factor receptor bound protein 2-associated protein 3 K09593|1|5e-45|185|xla:734248|GRB2-associated-binding protein 1;K08091|2|1e-42|177|shr:100928367|growth factor receptor bound protein 2-associated protein 2 - GO:0008289//lipid binding GO:0002573//myeloid leukocyte differentiation gi|31712032|ref|NP_853615.1|/0/GRB2-associated-binding protein 3 [Mus musculus] 68531 853 0.536666667 0.6 0.160936218 Up 0.128088683 1110020A21Rik RIKEN cDNA 1110020A21 gene - - - - - 329436 1780 0.52 0.58 0.157541277 Up 0.128088683 Gm14461 predicted gene 14461 - - - - gi|29244428|ref|NP_808511.1|/1.31114e-54/uncharacterized protein LOC329436 precursor [Mus musculus] 545471 2706 0.56 0.5 -0.163498732 Down 0.128088683 Zfp345 zinc finger protein 345 K09228|1|0.0|1237|mmu:545471|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|166197704|ref|NP_001030072.2|/0/zinc finger protein 345 [Mus musculus] 16847 5571 0.5 0.56 0.163498732 Up 0.128088683 Lepr leptin receptor K05062|1|0.0|2324|mmu:16847|leptin receptor GO:0016021//integral component of membrane;GO:0044421;GO:0016021//integral component of membrane;GO:0044421;GO:0016021//integral component of membrane;GO:0044421 GO:0004930//G-protein coupled receptor activity;GO:0042277//peptide binding;GO:0004930//G-protein coupled receptor activity;GO:0042277//peptide binding;GO:0004930//G-protein coupled receptor activity;GO:0042277//peptide binding GO:0044703;GO:0043086//negative regulation of catalytic activity;GO:0016125//sterol metabolic process;GO:0044237//cellular metabolic process;GO:0008585//female gonad development;GO:0048545//response to steroid hormone;GO:0019221//cytokine-mediated signaling pathway;GO:0000165//MAPK cascade;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0031667//response to nutrient levels;GO:0044703;GO:0043086//negative regulation of catalytic activity;GO:0016125//sterol metabolic process;GO:0044237//cellular metabolic process;GO:0008585//female gonad development;GO:0048545//response to steroid hormone;GO:0019221//cytokine-mediated signaling pathway;GO:0000165//MAPK cascade;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0031667//response to nutrient levels;GO:0044703;GO:0043086//negative regulation of catalytic activity;GO:0016125//sterol metabolic process;GO:0044237//cellular metabolic process;GO:0008585//female gonad development;GO:0048545//response to steroid hormone;GO:0019221//cytokine-mediated signaling pathway;GO:0000165//MAPK cascade;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0031667//response to nutrient levels "gi|148698917|gb|EDL30864.1|/0/leptin receptor, isoform CRA_b, partial [Mus musculus]" 100169889 865 0.523333333 0.583333333 0.156590363 Up 0.128088683 Peg3os Peg3 opposite strand K09230|1|4e-15|84.3|rno:103691034|SCAN domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0006139//nucleobase-containing compound metabolic process;GO:0010467//gene expression;GO:0012501//programmed cell death;GO:0040007//growth gi|758818575|ref|NP_001291745.1|/2.90857e-14/paternally-expressed gene 3 protein [Rattus norvegicus] 237886 3856 0.12 0.156666667 0.38466385 Up 0.128013464 Slfn9 schlafen 9 K04613|1|8e-10|69.3|rno:297590|vomeronasal 2 receptor GO:0044464 - - gi|116089296|ref|NP_766384.2|/0/schlafen 9 [Mus musculus] 75854 852 0.123333333 0.16 0.375509135 Up 0.128013464 4930579J19Rik RIKEN cDNA 4930579J19 gene - - - - - 353328 8553 0.12 0.156666667 0.38466385 Up 0.128013464 Muc6 "mucin 6, gastric" K13908|1|0.0|868|ecb:100147340|mucin-5B - - - gi|32171192|ref|NP_859418.1|/0/mucin-6 precursor [Mus musculus] 59040 4250.36 17.29 17.61666667 0.027003102 Up 0.128013464 Rhot1 ras homolog family member T1 "K07870|1|0.0|1287|mmu:59040|Ras homolog gene family, member T1" GO:0031306//intrinsic component of mitochondrial outer membrane;GO:0031306//intrinsic component of mitochondrial outer membrane GO:0046914//transition metal ion binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0046872//metal ion binding "GO:0032481//positive regulation of type I interferon production;GO:0042592//homeostatic process;GO:0012501//programmed cell death;GO:0034643//establishment of mitochondrion localization, microtubule-mediated;GO:0009154//purine ribonucleotide catabolic process;GO:0031347//regulation of defense response;GO:0035556//intracellular signal transduction;GO:0042592//homeostatic process;GO:0012501//programmed cell death;GO:0034643//establishment of mitochondrion localization, microtubule-mediated;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction" "gi|148683685|gb|EDL15632.1|/0/ras homolog gene family, member T1, isoform CRA_c, partial [Mus musculus]" 66468 2605 0.12 0.156666667 0.38466385 Up 0.128013464 Ska1 spindle and kinetochore associated complex subunit 1 - GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0000777//condensed chromosome kinetochore;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0000777//condensed chromosome kinetochore GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0031109//microtubule polymerization or depolymerization;GO:0007067//mitotic nuclear division;GO:0031109//microtubule polymerization or depolymerization;GO:0007067//mitotic nuclear division gi|256355203|ref|NP_079857.3|/3.48697e-142/spindle and kinetochore-associated protein 1 [Mus musculus] 271457 2364 17.41 17.74333333 0.027360863 Up 0.128013464 Rab5a "RAB5A, member RAS oncogene family" K07887|1|6e-119|431|mmu:271457|Ras-related protein Rab-5A GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0031252//cell leading edge;GO:0048770;GO:0030667//secretory granule membrane;GO:0044425;GO:0005856//cytoskeleton;GO:0005769//early endosome;GO:0030136//clathrin-coated vesicle GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0017076//purine nucleotide binding GO:0046847//filopodium assembly;GO:0048731//system development;GO:0014909//smooth muscle cell migration;GO:0048168//regulation of neuronal synaptic plasticity;GO:0006887//exocytosis;GO:0008284//positive regulation of cell proliferation;GO:0031623//receptor internalization;GO:0045184//establishment of protein localization;GO:0048869//cellular developmental process;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction gi|13385374|ref|NP_080163.1|/5.34319e-118/ras-related protein Rab-5A [Mus musculus] 22632 2324 14.09666667 14.43 0.03371724 Up 0.128013464 Yy1 YY1 transcription factor K09201|1|4e-156|554|mmu:22632|transcription factor YY GO:0016020//membrane;GO:0034399//nuclear periphery;GO:0043234//protein complex;GO:0000790//nuclear chromatin "GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0003712//transcription cofactor activity;GO:0000217//DNA secondary structure binding;GO:0000975//regulatory region DNA binding" GO:0033036;GO:0008202//steroid metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0000725//recombinational repair;GO:0043010//camera-type eye development;GO:0009411//response to UV;GO:0003002//regionalization;GO:0006996//organelle organization;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0034694//response to prostaglandin gi|31982421|ref|NP_033563.2|/3.13884e-155/transcriptional repressor protein YY1 [Mus musculus] 52036 4906.15 18.64666667 18.97333333 0.025055408 Up 0.128013464 Ppp6r3 "protein phosphatase 6, regulatory subunit 3" K15501|1|0.0|1601|mmu:52036|serine/threonine-protein phosphatase 6 regulatory subunit 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0010921//regulation of phosphatase activity gi|255918186|ref|NP_083275.1|/0/serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform 1 [Mus musculus] 12848 3304.64 16.27 15.93666667 -0.029864346 Down 0.128013464 Cops2 COP9 signalosome subunit 2 K12176|1|0.0|831|clv:102088645|COP9 signalosome complex subunit 2 - - - - 74061 1434 0.176666667 0.136666667 -0.37036845 Down 0.127816014 4933404K08Rik RIKEN cDNA 4933404K08 gene - - - - "gi|148700632|gb|EDL32579.1|/1.73476e-51/mCG144850, partial [Mus musculus]" 100044193 2514 0.153333333 0.196666667 0.359081093 Up 0.127816014 Gm20939 "predicted gene, 20939" K09228|1|0.0|788|mmu:102632383|KRAB domain-containing zinc finger protein - - - gi|402232750|ref|NP_001019902.2|/0/uncharacterized protein LOC100044193 [Mus musculus] 268890 2467 0.176666667 0.136666667 -0.37036845 Down 0.127816014 Lsamp limbic system-associated membrane protein K06772|1|4e-172|607|mmu:268890|limbic system-associated membrane protein GO:0031224//intrinsic component of membrane - GO:0022610 gi|30425330|ref|NP_780757.1|/3.34544e-171/limbic system-associated membrane protein precursor [Mus musculus] 73673 883 0.126666667 0.163333333 0.366782331 Up 0.127816014 Rec114 REC114 meiotic recombination protein - - - GO:0022403;GO:0006259//DNA metabolic process gi|259906436|ref|NP_082874.1|/3.81858e-134/meiotic recombination protein REC114 [Mus musculus] 56527 4922 0.153333333 0.196666667 0.359081093 Up 0.127816014 Mast1 microtubule associated serine/threonine kinase 1 K08789|1|0.0|2654|mmu:56527|microtubule-associated serine/threonine kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0016020//membrane GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding GO:0006996//organelle organization;GO:0035556//intracellular signal transduction;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process gi|125628634|ref|NP_064329.2|/0/microtubule-associated serine/threonine-protein kinase 1 [Mus musculus] 102448 3860 0.15 0.193333333 0.366127899 Up 0.127816014 Xylb xylulokinase homolog (H. influenzae) K00854|1|0.0|782|mmu:102448|xylulokinase [EC:2.7.1.17] - "GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0032550;GO:0016773//phosphotransferase activity, alcohol group as acceptor" GO:0019321;GO:0006796//phosphate-containing compound metabolic process;GO:0005975//carbohydrate metabolic process gi|84794607|ref|NP_001028381.1|/0/xylulose kinase isoform 1 [Mus musculus] 69568 4812.84 6.276666667 6.456666667 0.040790954 Up 0.127590357 Vkorc1l1 "vitamin K epoxide reductase complex, subunit 1-like 1" K05357|1|5e-95|352|rno:399684|vitamin-K-epoxide reductase (warfarin-sensitive) [EC:1.17.4.4] GO:0016020//membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0006775;GO:0006775;GO:0006775 gi|556503385|ref|NP_001273311.1|/1.8039e-65/vitamin K epoxide reductase complex subunit 1-like protein 1 isoform 3 [Mus musculus] 76022 7546 6.546666667 6.366666667 -0.040222291 Down 0.127590357 Gon4l gon-4-like (C.elegans) K15196|1|5e-27|127|mze:101481634|transcription factor IIIB 90 kDa subunit;K17408|2|3e-12|78.6|asn:102387036|small subunit ribosomal protein S29;K08451|5|8e-10|70.5|aqu:100635280|G protein-coupled receptor 64 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0030098//lymphocyte differentiation;GO:0006351//transcription, DNA-templated;GO:0030098//lymphocyte differentiation;GO:0006351//transcription, DNA-templated" gi|226443057|ref|NP_081665.2|/0/GON-4-like protein isoform 2 [Mus musculus] 72699 1987 6.023333333 5.846666667 -0.042947758 Down 0.127590357 Lime1 Lck interacting transmembrane adaptor 1 - GO:0019814;GO:0031224//intrinsic component of membrane GO:0019900//kinase binding GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0043408//regulation of MAPK cascade;GO:0042348//NF-kappaB import into nucleus;GO:0010522//regulation of calcium ion transport into cytosol gi|12963783|ref|NP_076173.1|/1.29616e-122/lck-interacting transmembrane adapter 1 precursor [Mus musculus] 329559 4610 7.286666667 7.47 0.035849248 Up 0.127590357 Zfp335 zinc finger protein 335 K09228|1|3e-46|190|gja:107107226|KRAB domain-containing zinc finger protein - - - - 21780 3918 6.723333333 6.903333333 0.03811647 Up 0.127590357 Tfam "transcription factor A, mitochondrial" "K11830|1|4e-122|442|mmu:21780|transcription factor A, mitochondrial" GO:0043234//protein complex;GO:0005759//mitochondrial matrix GO:0044212//transcription regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding "GO:0000959//mitochondrial RNA metabolic process;GO:0006261//DNA-dependent DNA replication;GO:0007005//mitochondrion organization;GO:0006352//DNA-templated transcription, initiation" "gi|6678303|ref|NP_033386.1|/3.15988e-121/transcription factor A, mitochondrial precursor [Mus musculus]" 14815 6345 6.203333333 6.38 0.040512774 Up 0.127590357 Nr3c1 "nuclear receptor subfamily 3, group C, member 1" K05771|1|0.0|1459|mmu:14815|glucocorticoid receptor GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0044327//dendritic spine head;GO:0044444//cytoplasmic part GO:0008289//lipid binding;GO:0005102//receptor binding;GO:0003712//transcription cofactor activity;GO:0003707//steroid hormone receptor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0043566//structure-specific DNA binding;GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0031072//heat shock protein binding GO:0043065//positive regulation of apoptotic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0031958;GO:0033145//positive regulation of intracellular steroid hormone receptor signaling pathway;GO:0009628//response to abiotic stimulus;GO:0043434//response to peptide hormone;GO:0048167//regulation of synaptic plasticity;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0006704//glucocorticoid biosynthetic process;GO:0051094//positive regulation of developmental process;GO:0014047//glutamate secretion;GO:0035270//endocrine system development;GO:0032026//response to magnesium ion;GO:0060443//mammary gland morphogenesis;GO:0071385//cellular response to glucocorticoid stimulus;GO:0048511//rhythmic process;GO:0043114//regulation of vascular permeability;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006338//chromatin remodeling;GO:0030323//respiratory tube development;GO:0006094//gluconeogenesis;GO:0043401//steroid hormone mediated signaling pathway gi|121247453|ref|NP_032199.3|/0/glucocorticoid receptor [Mus musculus] 68961 1644 15.70333333 16.02333333 0.029103471 Up 0.127580955 Phkg2 "phosphorylase kinase, gamma 2 (testis)" K00871|1|0.0|796|mmu:68961|phosphorylase kinase gamma subunit [EC:2.7.11.19] GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0032550;GO:0005515//protein binding;GO:0004683//calmodulin-dependent protein kinase activity GO:0005980//glycogen catabolic process;GO:0019318//hexose metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process "gi|188035881|ref|NP_081164.2|/0/phosphorylase b kinase gamma catalytic chain, liver/testis isoform [Mus musculus]" 66245 1488 15.59333333 15.91666667 0.029608871 Up 0.127580955 Hspbp1 "HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1" K09562|1|4e-147|523|rro:104674762|hsp70-interacting protein - - - - 75660 998 14.18666667 14.50333333 0.031848866 Up 0.127580955 Lin37 lin-37 homolog (C. elegans) - - - - gi|21313004|ref|NP_083653.1|/7.29378e-127/protein lin-37 homolog isoform 1 [Mus musculus] 68776 1220 13.97333333 14.29 0.0323297 Up 0.127580955 Taf11 TATA-box binding protein associated factor 11 K03135|1|2e-86|321|mmu:68776|transcription initiation factor TFIID subunit 11 GO:0005667//transcription factor complex GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity;GO:0008134//transcription factor binding GO:0043921;GO:0006366//transcription from RNA polymerase II promoter gi|30794436|ref|NP_081112.1|/1.90864e-85/transcription initiation factor TFIID subunit 11 [Mus musculus] 216395 1393 17.67333333 17.35666667 -0.026084263 Down 0.127580955 Tmem5 transmembrane protein 5 - GO:0016021//integral component of membrane - - gi|23346449|ref|NP_694699.1|/0/transmembrane protein 5 [Mus musculus] 230234 4299 1.526666667 1.613333333 0.079659449 Up 0.12756215 Fam206a "family with sequence similarity 206, member A" K09596|1|2e-08|65.1|smm:Smp_154770|signal peptide peptidase-like 2A [EC:3.4.23.-] - - - - 223881 2203 1.563333333 1.653333333 0.080752198 Up 0.12756215 Rnd1 Rho family GTPase 1 K07531|1|1e-118|429|mmu:223881|Rho family GTPase 1 GO:0016020//membrane;GO:0070161;GO:0043232;GO:0044444//cytoplasmic part GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity GO:0007155//cell adhesion;GO:0042551//neuron maturation;GO:0030036//actin cytoskeleton organization;GO:0006935//chemotaxis;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction gi|27369880|ref|NP_766200.1|/1.0913e-117/rho-related GTP-binding protein Rho6 precursor [Mus musculus] 74328 568 1.453333333 1.54 0.083564717 Up 0.12756215 1700047E10Rik RIKEN cDNA 1700047E10 gene - GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane "GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006644//phospholipid metabolic process;GO:0046165 gi|755550121|ref|XP_011243610.1|/3.49246e-32/PREDICTED: disks large homolog 5-like [Mus musculus] 76775 3568 1.766666667 1.673333333 -0.078304995 Down 0.12756215 Slc10a7 "solute carrier family 10 (sodium/bile acid cotransporter family), member 7" "K14347|1|1e-158|563|mmu:76775|solute carrier family 10 (sodium/bile acid cotransporter), member 7" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport;GO:0030001//metal ion transport "gi|148678912|gb|EDL10859.1|/6.21602e-131/RIKEN cDNA 2410193C02, isoform CRA_a, partial [Mus musculus]" 329540 5631 1.613333333 1.523333333 -0.082812882 Down 0.12756215 Nol4l nucleolar protein 4-like - - - - gi|197245335|ref|NP_001127772.1|/0/nucleolar protein 4-like isoform 2 [Mus musculus] 242838 2951 0.053333333 0.02 -1.415037499 Down 0.127468126 Lrrd1 leucine rich repeats and death domain containing 1 K19613|1|6e-53|212|bfo:BRAFLDRAFT_214464|leucine-rich repeat protein SHOC2 - - - gi|161086957|ref|NP_766467.2|/0/leucine-rich repeat and death domain-containing protein 1 [Mus musculus] 140557 4056 0.02 0.05 1.321928095 Up 0.127468126 Smc1b structural maintenance of chromosomes 1B K06636|1|0.0|2316|mmu:140557|structural maintenance of chromosome 1 GO:0000798//nuclear cohesin complex;GO:0000795//synaptonemal complex GO:0032550;GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process;GO:0051276//chromosome organization;GO:0007059//chromosome segregation;GO:0022403 gi|17978290|ref|NP_536718.1|/0/structural maintenance of chromosomes protein 1B [Mus musculus] 170638 4652 0.016666667 0.043333333 1.378511623 Up 0.127468126 Hpcal4 hippocalcin-like 4 K19936|1|3e-99|366|lcm:102352665|visinin-like protein 1 - - - gi|953846243|ref|XP_001503492.2|/2.24972e-105/PREDICTED: hippocalcin-like protein 4 [Equus caballus] 116911 4221 0.046666667 0.016666667 -1.485426827 Down 0.127468126 Cts8-ps "cathepsin 8, pseudogene" K01365|1|5e-53|122|cge:100772033|cathepsin L [EC:3.4.22.15] - - - gi|564390208|ref|XP_225128.7|/6.30694e-62/PREDICTED: LOW QUALITY PROTEIN: cathepsin M isoform X2 [Rattus norvegicus] 622645 3213 0.053333333 0.02 -1.415037499 Down 0.127468126 Tmem200c transmembrane protein 200C - - - - gi|331284197|ref|NP_001193590.1|/0/transmembrane protein 200C [Mus musculus] 18183 3992.62 0.05 0.02 -1.321928095 Down 0.127468126 Nrg3 neuregulin 3 K05457|1|0.0|1107|mmu:18183|neuregulin 3 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005102//receptor binding;GO:0005102//receptor binding;GO:0005102//receptor binding GO:0035556//intracellular signal transduction;GO:0060592//mammary gland formation;GO:0035556//intracellular signal transduction;GO:0060592//mammary gland formation;GO:0035556//intracellular signal transduction;GO:0060592//mammary gland formation "gi|6679128|ref|NP_032760.1|/0/pro-neuregulin-3, membrane-bound isoform isoform 1 [Mus musculus]" 18675 6265 0.016666667 0.043333333 1.378511623 Up 0.127468126 Phex "phosphate regulating endopeptidase homolog, X-linked" K08636|1|0.0|1495|mmu:18675|phosphate-regulating neutral endopeptidase [EC:3.4.24.-] GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0044444//cytoplasmic part GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity GO:0048731//system development;GO:0009888//tissue development;GO:0001503//ossification;GO:0006793//phosphorus metabolic process;GO:0007154//cell communication;GO:0036211//protein modification process gi|6755050|ref|NP_035207.1|/0/metalloendopeptidase homolog PEX [Mus musculus] 20495 4660 0.046666667 0.016666667 -1.485426827 Down 0.127468126 Slc12a1 "solute carrier family 12, member 1" "K14425|1|0.0|2021|mmu:20495|solute carrier family 12 (sodium/potassium/chloride transporter), member 1" GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459 GO:0005488//binding;GO:0046873//metal ion transmembrane transporter activity;GO:0015377//cation:chloride symporter activity;GO:0005488//binding;GO:0046873//metal ion transmembrane transporter activity;GO:0015377//cation:chloride symporter activity GO:0044763;GO:0003096//renal sodium ion transport;GO:0035828;GO:0042592//homeostatic process;GO:0044767//single-organism developmental process;GO:0015698//inorganic anion transport;GO:0044763;GO:0003096//renal sodium ion transport;GO:0035828;GO:0042592//homeostatic process;GO:0044767//single-organism developmental process;GO:0015698//inorganic anion transport gi|119226231|ref|NP_899197.2|/0/solute carrier family 12 member 1 isoform A [Mus musculus] 244281 7252 0.046666667 0.016666667 -1.485426827 Down 0.127468126 Myo16 myosin XVI K17481|1|0.0|2946|mmu:244281|myosin XVI - - - - 622124 3515 0.043333333 0.016666667 -1.378511623 Down 0.127468126 Gm20750 "predicted gene, 20750" - - - - gi|148703282|gb|EDL35229.1|/3.92734e-19/mCG148192 [Mus musculus] 12677 3234 0.02 0.053333333 1.415037499 Up 0.127468126 Vsx2 visual system homeobox 2 K09336|1|2e-172|609|cfa:490780|visual system homeobox protein 2 GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0003407//neural retina development;GO:0050953//sensory perception of light stimulus;GO:0030154//cell differentiation;GO:0009653//anatomical structure morphogenesis;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0003407//neural retina development;GO:0030154//cell differentiation;GO:0009653//anatomical structure morphogenesis;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter gi|6671750|ref|NP_031727.1|/3.8933e-162/visual system homeobox 2 isoform 2 [Mus musculus] 12951 2903 0.583333333 0.646666667 0.14870173 Up 0.127449321 Crx cone-rod homeobox K09337|1|2e-129|439|rro:104673377|cone-rod homeobox protein GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0030275//LRR domain binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0030275//LRR domain binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0009653//anatomical structure morphogenesis;GO:0048511//rhythmic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0043010//camera-type eye development;GO:0045666//positive regulation of neuron differentiation;GO:0009653//anatomical structure morphogenesis;GO:0048511//rhythmic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0043010//camera-type eye development;GO:0045666//positive regulation of neuron differentiation gi|164519071|ref|NP_001106801.1|/1.45685e-136/cone-rod homeobox protein isoform 2 [Mus musculus] 19696 2584 0.573333333 0.516666667 -0.150140349 Down 0.127449321 Rel reticuloendotheliosis oncogene K09254|1|0.0|1157|mmu:19696|c-Rel proto-oncogene protein GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0060548//negative regulation of cell death;GO:0042090" gi|112181204|ref|NP_033070.2|/0/proto-oncogene c-Rel [Mus musculus] 385674 5942 0.5 0.556666667 0.154885602 Up 0.127449321 Zfp174 zinc finger protein 174 K09230|1|0.0|829|mmu:385674|SCAN domain-containing zinc finger protein - - - gi|124487047|ref|NP_001074686.1|/0/zinc finger protein 174 [Mus musculus] 100515 6816 0.513333333 0.57 0.151065974 Up 0.127449321 Zfp518b zinc finger protein 518B K09228|1|2e-12|79.0|bfo:BRAFLDRAFT_66686|KRAB domain-containing zinc finger protein - - - gi|295444872|ref|NP_001074613.2|/0/zinc finger protein 518B [Mus musculus] 67886 7823 1.996666667 2.1 0.072795826 Up 0.127439919 Camsap2 "calmodulin regulated spectrin-associated protein family, member 2" K17493|1|0.0|2514|mmu:67886|calmodulin-regulated spectrin-associated protein GO:0015630//microtubule cytoskeleton GO:0015631//tubulin binding - gi|124486889|ref|NP_001074829.1|/0/calmodulin-regulated spectrin-associated protein 2 [Mus musculus] 102443350 3169 2.166666667 2.27 0.06721508 Up 0.127439919 Xndc1 Xrcc1 N-terminal domain containing 1 K04965|1|8e-138|494|cge:100689218|transient receptor potential cation channel subfamily C member 2 - - - gi|557878583|ref|NP_001273618.1|/0/XRCC1 N-terminal domain-related [Mus musculus] 72326 1898 2.086666667 2.19 0.069730713 Up 0.127439919 2500004C02Rik RIKEN cDNA 2500004C02 gene K11471|1|1e-09|67.8|cge:100761070|additional sex combs-like protein GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0043169//cation binding;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006644//phospholipid metabolic process;GO:0046165 "gi|148674077|gb|EDL06024.1|/1.87071e-30/mCG140752, isoform CRA_b, partial [Mus musculus]" 209558 2815 2.096666667 2.2 0.069406007 Up 0.127439919 Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 K01513|1|0.0|1800|mmu:209558|ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9] GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0001871;GO:0038024//cargo receptor activity;GO:0004527//exonuclease activity;GO:0004551//nucleotide diphosphatase activity GO:0002376//immune system process;GO:0051145//smooth muscle cell differentiation;GO:0015698//inorganic anion transport;GO:0009141//nucleoside triphosphate metabolic process "gi|148672841|gb|EDL04788.1|/0/ectonucleotide pyrophosphatase/phosphodiesterase 3, partial [Mus musculus]" 12530 3643 2.026666667 2.123333333 0.067222049 Up 0.127439919 Cdc25a cell division cycle 25A K06645|1|0.0|998|mmu:12530|M-phase inducer phosphatase 1 [EC:3.1.3.48] GO:0043231//intracellular membrane-bounded organelle GO:0004721//phosphoprotein phosphatase activity;GO:0019900//kinase binding GO:0006464//cellular protein modification process;GO:0009411//response to UV;GO:0000087//mitotic M phase gi|92373436|ref|NP_031684.3|/0/M-phase inducer phosphatase 1 [Mus musculus] 81701 1154 2.053333333 1.953333333 -0.072029686 Down 0.127439919 Egfl8 EGF-like domain 8 K06824|1|3e-14|82.0|bfo:BRAFLDRAFT_123314|nephronectin - GO:0046872//metal ion binding - gi|226342953|ref|NP_690886.3|/2.15099e-176/epidermal growth factor-like protein 8 precursor [Mus musculus] 77305 4313 13.42333333 13.11 -0.034075286 Down 0.127270676 Wdr82 WD repeat domain containing 82 K14962|1|1e-177|627|pale:102898949|COMPASS component SWD2 GO:0035097//histone methyltransferase complex;GO:0044427;GO:0008287//protein serine/threonine phosphatase complex GO:0008092//cytoskeletal protein binding;GO:0018024//histone-lysine N-methyltransferase activity GO:0034968//histone lysine methylation gi|926720695|ref|XP_005695941.2|/1.00841e-176/PREDICTED: WD repeat-containing protein 82 [Capra hircus] 16889 2991 16.7 17.01333333 0.026817726 Up 0.127270676 Lipa lysosomal acid lipase A K01052|1|0.0|799|mmu:16889|lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] GO:0000323//lytic vacuole;GO:0000323//lytic vacuole GO:0052689//carboxylic ester hydrolase activity;GO:0052689//carboxylic ester hydrolase activity GO:0006952//defense response;GO:0030323//respiratory tube development;GO:0006629//lipid metabolic process;GO:0006066//alcohol metabolic process;GO:0001894//tissue homeostasis;GO:0032787//monocarboxylic acid metabolic process;GO:0032989;GO:0006952//defense response;GO:0030323//respiratory tube development;GO:0006629//lipid metabolic process;GO:0006066//alcohol metabolic process;GO:0001894//tissue homeostasis;GO:0032787//monocarboxylic acid metabolic process;GO:0032989 gi|161760651|ref|NP_067435.3|/0/lysosomal acid lipase/cholesteryl ester hydrolase precursor [Mus musculus] 380755 1213 14.03666667 14.35 0.031850362 Up 0.127270676 Lsmem1 leucine-rich single-pass membrane protein 1 - GO:0031224//intrinsic component of membrane - - gi|625197900|ref|XP_007641032.1|/1.32391e-54/PREDICTED: leucine-rich single-pass membrane protein 1 isoform X2 [Cricetulus griseus] 107652 3085.24 15.52 15.21333333 -0.028792267 Down 0.127270676 Uap1 UDP-N-acetylglucosamine pyrophosphorylase 1 K00972|1|0.0|1050|mmu:107652|UDP-N-acetylglucosamine/UDP-N-acetylgalactosamine diphosphorylase [EC:2.7.7.23 2.7.7.83] - - - - 223754 3248 14.6 14.91333333 0.030634387 Up 0.127270676 Tbc1d22a "TBC1 domain family, member 22a" K20360|1|0.0|1012|mmu:223754|TBC1 domain family member 2 GO:0044464 GO:0042802//identical protein binding - gi|74178361|dbj|BAE32447.1|/0/unnamed protein product [Mus musculus] 269831 2490 12.94333333 13.25333333 0.03414605 Up 0.127270676 Tspan12 tetraspanin 12 K17355|1|2e-173|612|mmu:269831|tetraspanin-12 GO:0016021//integral component of membrane GO:0004888//transmembrane signaling receptor activity GO:0003407//neural retina development;GO:0001525//angiogenesis;GO:0007165//signal transduction gi|918630920|ref|XP_013358742.1|/5.98928e-175/PREDICTED: tetraspanin-12 [Chinchilla lanigera] 19070 2822.79 13.41 13.72333333 0.033321711 Up 0.127270676 Mob4 "MOB family member 4, phocein" "K06685|1|2e-06|57.8|pxy:105387850|MOB kinase activator 1;K03847|2|3e-06|38.5|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" GO:0000139//Golgi membrane "GO:0043169//cation binding;GO:0019899//enzyme binding;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006796//phosphate-containing compound metabolic process;GO:0016192//vesicle-mediated transport gi|641711232|ref|XP_008144777.1|/3.20117e-125/PREDICTED: uncharacterized protein LOC103290627 [Eptesicus fuscus] 11792 1307 16.20666667 15.89333333 -0.028165658 Down 0.127270676 Apex1 apurinic/apyrimidinic endonuclease 1 K10771|1|6e-168|592|mmu:11792|AP endonuclease 1 [EC:4.2.99.18] GO:0005815//microtubule organizing center;GO:0016604//nuclear body;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0016835//carbon-oxygen lyase activity;GO:0042578//phosphoric ester hydrolase activity;GO:0003712//transcription cofactor activity;GO:0004527//exonuclease activity;GO:0043169//cation binding;GO:0003677//DNA binding;GO:0004520//endodeoxyribonuclease activity;GO:0003682//chromatin binding;GO:0008134//transcription factor binding "GO:0006351//transcription, DNA-templated;GO:0014909//smooth muscle cell migration;GO:0034614//cellular response to reactive oxygen species;GO:0043487//regulation of RNA stability;GO:0044710;GO:0019725//cellular homeostasis;GO:0000084//mitotic S phase;GO:0051591//response to cAMP;GO:0035510;GO:0044767//single-organism developmental process;GO:0032870//cellular response to hormone stimulus;GO:0006281//DNA repair" gi|6753086|ref|NP_033817.1|/4.89987e-167/DNA-(apurinic or apyrimidinic site) lyase [Mus musculus] 19092 4696 0.056666667 0.026666667 -1.087462841 Down 0.127176652 Prkg2 "protein kinase, cGMP-dependent, type II" K19477|1|0.0|1536|mmu:19092|cGMP-dependent protein kinase 2 [EC:2.7.11.12] GO:0044459;GO:0044444//cytoplasmic part GO:0032550;GO:0030551//cyclic nucleotide binding;GO:0004690//cyclic nucleotide-dependent protein kinase activity GO:0044710;GO:0006464//cellular protein modification process;GO:0007623//circadian rhythm;GO:0006796//phosphate-containing compound metabolic process;GO:0006807//nitrogen compound metabolic process;GO:0007599//hemostasis;GO:0007154//cell communication;GO:0032768 gi|188219585|ref|NP_032952.3|/0/cGMP-dependent protein kinase 2 [Mus musculus] 14729 2215 0.03 0.06 1 Up 0.127176652 Gp5 glycoprotein 5 (platelet) K06260|1|0.0|991|mmu:14729|platelet glycoprotein V GO:0031224//intrinsic component of membrane;GO:0044464 GO:0005515//protein binding GO:0031589//cell-substrate adhesion;GO:0010543//regulation of platelet activation gi|31982322|ref|NP_032174.2|/0/platelet glycoprotein V precursor [Mus musculus] 17952 6705 0.026666667 0.056666667 1.087462841 Up 0.127176652 Naip6 "NLR family, apoptosis inhibitory protein 6" K12807|1|0.0|2801|mmu:17952|baculoviral IAP repeat-containing protein 1 - - - - 18996 3801 0.033333333 0.066666667 1 Up 0.127176652 Pou4f1 "POU domain, class 4, transcription factor 1" "K09366|1|4e-90|336|ocu:100344822|POU domain transcription factor, class 4" GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding" GO:0019230//proprioception;GO:0006366//transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0001708//cell fate specification;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007422//peripheral nervous system development;GO:0021545//cranial nerve development;GO:0007631//feeding behavior;GO:0021538//epithalamus development;GO:0016477//cell migration "gi|156938250|ref|NP_035273.3|/3.09251e-89/POU domain, class 4, transcription factor 1 [Mus musculus]" 270757 2328 0.053333333 0.026666667 -1 Down 0.127176652 Bpifc BPI fold containing family C K14415|1|2e-84|316|clv:102087886|tRNA-splicing ligase RtcB [EC:6.5.1.3];K05399|2|3e-42|176|mdo:100032863|lipopolysaccharide-binding protein;K08761|5|2e-39|166|lcm:102350400|phospholipid transfer protein - GO:0005488//binding - "gi|148689482|gb|EDL21429.1|/0/bactericidal/permeability-increasing protein-like 2, partial [Mus musculus]" 50878 4246 0.06 0.03 -1 Down 0.127176652 Stag3 stromal antigen 3 K13055|1|0.0|2189|mmu:50878|cohesin complex subunit SA-3 - - - - 100504235 3401 0.02 0.046666667 1.222392421 Up 0.127176652 Gm20125 "predicted gene, 20125" - - - - - 12941 5206 0.033333333 0.066666667 1 Up 0.127176652 Pcdha5 protocadherin alpha 5 K16493|1|0.0|1763|mmu:12941|protocadherin alpha GO:0016021//integral component of membrane GO:0046872//metal ion binding GO:0048731//system development;GO:0016337//single organismal cell-cell adhesion gi|20137002|ref|NP_034089.1|/0/protocadherin alpha-5 precursor [Mus musculus] 100102 3512 0.06 0.03 -1 Down 0.127176652 Pcsk9 proprotein convertase subtilisin/kexin type 9 K13050|1|0.0|1309|mmu:100102|proprotein convertase subtilisin/kexin type 9 [EC:3.4.21.-] - - - - 11989 2277 0.026666667 0.06 1.169925001 Up 0.127176652 Slc7a3 "solute carrier family 7 (cationic amino acid transporter, y+ system), member 3" "K13865|1|0.0|1032|mmu:11989|solute carrier family 7 (cationic amino acid transporter), member 3" GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0015171//amino acid transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity GO:0006865//amino acid transport;GO:0009966//regulation of signal transduction;GO:0006812//cation transport;GO:0006865//amino acid transport;GO:0009966//regulation of signal transduction;GO:0006812//cation transport gi|6671600|ref|NP_031541.1|/0/cationic amino acid transporter 3 [Mus musculus] 100043034 3998 0.03 0.06 1 Up 0.127176652 Rex2 reduced expression 2 K09228|1|0.0|1375|mmu:667666|KRAB domain-containing zinc finger protein - - - - 64450 2971 0.066666667 0.033333333 -1 Down 0.127176652 Gpr85 G protein-coupled receptor 85 K04302|1|0.0|720|ecb:100055809|G protein-coupled receptor 85 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|11560065|ref|NP_071590.1|/0/probable G-protein coupled receptor 85 [Rattus norvegicus] 382221 2148 0.053333333 0.026666667 -1 Down 0.127176652 Gm1141 predicted gene 1141 - - - - - 14581 2650 0.023333333 0.053333333 1.192645078 Up 0.127176652 Gfi1 growth factor independent 1 K09223|1|0.0|797|mmu:14581|growth factor independent 1 GO:0034399//nuclear periphery;GO:0043234//protein complex;GO:0044451;GO:0034399//nuclear periphery;GO:0043234//protein complex;GO:0044451 GO:0000975//regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0000975//regulatory region DNA binding;GO:0046914//transition metal ion binding GO:0032769//negative regulation of monooxygenase activity;GO:0000082//G1/S transition of mitotic cell cycle;GO:0009612//response to mechanical stimulus;GO:0044764;GO:0001708//cell fate specification;GO:0042471//ear morphogenesis;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0010975//regulation of neuron projection development;GO:0006366//transcription from RNA polymerase II promoter;GO:0002224//toll-like receptor signaling pathway;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0010894//negative regulation of steroid biosynthetic process;GO:0060113//inner ear receptor cell differentiation;GO:0032496//response to lipopolysaccharide;GO:0032769//negative regulation of monooxygenase activity;GO:0000082//G1/S transition of mitotic cell cycle;GO:0009612//response to mechanical stimulus;GO:0044764;GO:0001708//cell fate specification;GO:0042471//ear morphogenesis;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0010975//regulation of neuron projection development;GO:0006366//transcription from RNA polymerase II promoter;GO:0002224//toll-like receptor signaling pathway;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0010894//negative regulation of steroid biosynthetic process;GO:0060113//inner ear receptor cell differentiation;GO:0032496//response to lipopolysaccharide gi|390407652|ref|NP_001254550.1|/0/zinc finger protein Gfi-1 isoform 2 [Mus musculus] 100038525 872 0.026666667 0.056666667 1.087462841 Up 0.127176652 Gm10804 predicted gene 10804 - - - - "gi|148695679|gb|EDL27626.1|/5.37134e-40/mCG1040646, isoform CRA_a, partial [Mus musculus]" 320916 4332 0.06 0.03 -1 Down 0.127176652 Wscd2 WSC domain containing 2 K04730|1|3e-12|77.4|api:100159492|interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1];K00771|4|1e-11|75.5|mde:101891944|protein xylosyltransferase [EC:2.4.2.26] GO:0031224//intrinsic component of membrane - - gi|227496084|ref|NP_796266.2|/0/WSC domain-containing protein 2 [Mus musculus] 78784 2534 0.026666667 0.06 1.169925001 Up 0.127176652 Celf3 "CUGBP, Elav-like family member 3" K13207|1|0.0|744|ocu:100328677|CUG-BP- and ETR3-like factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0003723//RNA binding;GO:0003676//nucleic acid binding "GO:0048870//cell motility;GO:0048232//male gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0048870//cell motility;GO:0048232//male gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0048870//cell motility;GO:0048232//male gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0048870//cell motility;GO:0048232//male gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0048870//cell motility;GO:0048232//male gamete generation;GO:0000380//alternative mRNA splicing, via spliceosome" "gi|148706791|gb|EDL38738.1|/0/trinucleotide repeat containing 4, isoform CRA_d, partial [Mus musculus]" 232714 6488 0.02 0.046666667 1.222392421 Up 0.127176652 Mgam maltase-glucoamylase K12047|1|0.0|3618|mmu:232714|maltase-glucoamylase [EC:3.2.1.20 3.2.1.3] GO:0044459;GO:0031224//intrinsic component of membrane "GO:0005488//binding;GO:0004558//alpha-1,4-glucosidase activity" GO:0005982//starch metabolic process;GO:0044710;GO:0007586//digestion "gi|283483997|ref|NP_001164474.1|/0/maltase-glucoamylase, intestinal [Mus musculus]" 71818 2283 0.026666667 0.06 1.169925001 Up 0.127176652 3200001D21Rik RIKEN cDNA 3200001D21 gene - - - - - 23966 13186 0.053333333 0.023333333 -1.192645078 Down 0.127176652 Tenm4 teneurin transmembrane protein 4 K06252|1|5e-50|204|ngi:103724414|tenascin - - - gi|755522640|ref|XP_011240091.1|/0/PREDICTED: teneurin-4 isoform X3 [Mus musculus] 79235 5349 0.023333333 0.053333333 1.192645078 Up 0.127176652 Lrat lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) K00678|1|5e-108|395|mmu:79235|phosphatidylcholine-retinol O-acyltransferase [EC:2.3.1.135] GO:0031224//intrinsic component of membrane;GO:0005770//late endosome;GO:0031090//organelle membrane;GO:0005783//endoplasmic reticulum GO:0005501//retinoid binding;GO:0008374//O-acyltransferase activity GO:0001523//retinoid metabolic process;GO:0050953//sensory perception of light stimulus;GO:0046470//phosphatidylcholine metabolic process;GO:0007275//multicellular organism development gi|12963753|ref|NP_076113.1|/4.76605e-107/lecithin retinol acyltransferase [Mus musculus] 72832 2616 0.026666667 0.053333333 1 Up 0.127176652 Crtac1 cartilage acidic protein 1 K17307|1|4e-10|69.7|mze:101469880|fibulin 1/2 GO:0031012//extracellular matrix - - "gi|148709942|gb|EDL41888.1|/0/cartilage acidic protein 1, isoform CRA_a, partial [Mus musculus]" 16536 8301 0.05 0.023333333 -1.099535674 Down 0.127176652 Kcnq2 "potassium voltage-gated channel, subfamily Q, member 2" K04927|1|0.0|1604|mmu:16536|potassium voltage-gated channel KQT-like subfamily member 2 GO:0032991//macromolecular complex;GO:0033267;GO:0005887//integral component of plasma membrane;GO:0032991//macromolecular complex;GO:0033267;GO:0005887//integral component of plasma membrane GO:0008092//cytoskeletal protein binding;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0008092//cytoskeletal protein binding;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity GO:0042391//regulation of membrane potential;GO:0007154//cell communication;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0042391//regulation of membrane potential;GO:0007154//cell communication;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|725798567|ref|NP_001289817.1|/0/potassium voltage-gated channel subfamily KQT member 2 isoform 13 [Mus musculus] 72927 3103 0.05 0.023333333 -1.099535674 Down 0.127176652 Hepacam hepatocyte cell adhesion molecule K06499|1|2e-15|87.4|xma:102231054|carcinoembryonic antigen-related cell adhesion molecule - - - - 27413 4899 0.063333333 0.03 -1.078002512 Down 0.127176652 Abcb11 "ATP-binding cassette, sub-family B (MDR/TAP), member 11" "K05664|1|0.0|2568|mmu:27413|ATP-binding cassette, subfamily B (MDR/TAP), member 11" - - - gi|120432047|ref|NP_066302.2|/0/bile salt export pump [Mus musculus] 73100 2841 0.02 0.046666667 1.222392421 Up 0.127176652 2900092D14Rik RIKEN cDNA 2900092D14 gene - - - - "gi|148664508|gb|EDK96924.1|/2.75864e-31/mCG145686, partial [Mus musculus]" 239081 3212 0.023333333 0.05 1.099535674 Up 0.127176652 Tlr11 toll-like receptor 11 K14142|1|0.0|1687|mmu:239081|toll-like receptor 11 GO:0031224//intrinsic component of membrane - GO:0051707//response to other organism;GO:0006952//defense response;GO:0007154//cell communication gi|408684413|ref|NP_991388.2|/0/toll-like receptor 11 [Mus musculus] 60597 3553 0.03 0.063333333 1.078002512 Up 0.127176652 Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 K04435|1|0.0|1190|mmu:60597|mitogen-activated protein kinase 8 interacting protein 2 GO:0032991//macromolecular complex;GO:0044327//dendritic spine head;GO:0044297//cell body;GO:0044424 GO:0008092//cytoskeletal protein binding;GO:0019887//protein kinase regulator activity;GO:0019900//kinase binding "GO:0001934//positive regulation of protein phosphorylation;GO:0016358//dendrite development;GO:0032872//regulation of stress-activated MAPK cascade;GO:0051705;GO:0007618//mating;GO:0007612//learning;GO:0002209//behavioral defense response;GO:0035249//synaptic transmission, glutamatergic;GO:0007254//JNK cascade;GO:0051899//membrane depolarization;GO:0010469//regulation of receptor activity" gi|257096008|ref|NP_068740.3|/0/C-Jun-amino-terminal kinase-interacting protein 2 [Mus musculus] 114602 1783 0.06 0.03 -1 Down 0.127176652 Zmynd10 "zinc finger, MYND domain containing 10" K17656|1|2e-06|56.6|mze:101480763|mitochondrial splicing suppressor protein 51 GO:0044424 GO:0046914//transition metal ion binding - gi|31982595|ref|NP_444483.2|/0/zinc finger MYND domain-containing protein 10 [Mus musculus] 381845 3257 0.03 0.063333333 1.078002512 Up 0.127176652 Rnf225 ring finger protein 225 K05692|1|6e-06|56.2|pps:103784606|actin beta/gamma 1;K11997|2|8e-06|55.8|nvi:100123158|tripartite motif-containing protein 2/3 - - - - 214292 2918 0.023333333 0.05 1.099535674 Up 0.127176652 Syna syncytin a "K04257|1|2e-15|87.8|tup:102483054|olfactory receptor;K10279|2|5e-11|72.8|fpg:101911127|F-box and leucine-rich repeat protein 13;K14684|4|5e-09|66.2|ngi:103726559|solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41" - - - - 12773 2787 0.056666667 0.023333333 -1.280107919 Down 0.127176652 Ccr4 chemokine (C-C motif) receptor 4 K04179|1|0.0|676|mmu:12773|C-C chemokine receptor type 4 - - - - 14401 7568 0.06 0.026666667 -1.169925001 Down 0.127176652 Gabrb2 "gamma-aminobutyric acid (GABA) A receptor, subunit beta 2" K05181|1|0.0|900|rno:25451|gamma-aminobutyric acid receptor subunit beta GO:0044444//cytoplasmic part;GO:0097060//synaptic membrane;GO:0034702//ion channel complex GO:0005253//anion channel activity;GO:0005488//binding;GO:0005230//extracellular ligand-gated ion channel activity;GO:0016917//GABA receptor activity GO:0050954//sensory perception of mechanical stimulus;GO:0021675//nerve development;GO:0015698//inorganic anion transport;GO:0007270//neuron-neuron synaptic transmission;GO:0048666//neuron development;GO:0007186//G-protein coupled receptor signaling pathway gi|4503865|ref|NP_000804.1|/0/gamma-aminobutyric acid receptor subunit beta-2 isoform 2 precursor [Homo sapiens] 50765 3455 0.02 0.046666667 1.222392421 Up 0.127176652 Tfr2 transferrin receptor 2 K06503|1|6e-158|561|xtr:101734813|transferrin receptor GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424 GO:0016787//hydrolase activity;GO:0016787//hydrolase activity;GO:0016787//hydrolase activity;GO:0016787//hydrolase activity GO:0019538//protein metabolic process;GO:0006875//cellular metal ion homeostasis;GO:0019538//protein metabolic process;GO:0006875//cellular metal ion homeostasis;GO:0019538//protein metabolic process;GO:0006875//cellular metal ion homeostasis;GO:0019538//protein metabolic process;GO:0006875//cellular metal ion homeostasis gi|755514641|ref|XP_006504654.2|/0/PREDICTED: transferrin receptor protein 2 isoform X2 [Mus musculus] 74435 2650 0.023333333 0.053333333 1.192645078 Up 0.127176652 Lrriq3 leucine-rich repeats and IQ motif containing 3 K16606|1|2e-08|63.9|bom:102270936|leucine-rich repeat-containing protein 49 - - - gi|110347523|ref|NP_083214.2|/0/leucine-rich repeat and IQ domain-containing protein 3 [Mus musculus] 381293 8338 0.033333333 0.066666667 1 Up 0.127176652 Kif14 kinesin family member 14 K17915|1|0.0|3239|mmu:381293|kinesin family member 14 - - - gi|562902155|ref|NP_001274108.1|/0/kinesin-like protein KIF14 [Mus musculus] 268934 3231 0.03 0.063333333 1.078002512 Up 0.127176652 Grm4 "glutamate receptor, metabotropic 4" K04607|1|0.0|1623|mmu:268934|metabotropic glutamate receptor 4 GO:0031982//vesicle;GO:0042734//presynaptic membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0033267;GO:0031982//vesicle;GO:0042734//presynaptic membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0033267 GO:0005515//protein binding;GO:0001640//adenylate cyclase inhibiting G-protein coupled glutamate receptor activity;GO:0005515//protein binding;GO:0001640//adenylate cyclase inhibiting G-protein coupled glutamate receptor activity GO:0007270//neuron-neuron synaptic transmission;GO:0042981//regulation of apoptotic process;GO:0007611//learning or memory;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0030030//cell projection organization;GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade;GO:0015812//gamma-aminobutyric acid transport;GO:0007270//neuron-neuron synaptic transmission;GO:0042981//regulation of apoptotic process;GO:0007611//learning or memory;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0030030//cell projection organization;GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade;GO:0015812//gamma-aminobutyric acid transport gi|62945392|ref|NP_001013403.1|/0/metabotropic glutamate receptor 4 isoform 2 precursor [Mus musculus] 665306 2847 0.023333333 0.05 1.099535674 Up 0.127176652 3930402G23Rik RIKEN cDNA 3930402G23 gene - - - - gi|148690105|gb|EDL22052.1|/7.21068e-64/mCG17325 [Mus musculus] 215798 6505 0.173333333 0.136666667 -0.342887714 Down 0.126979202 Adgrg6 adhesion G protein-coupled receptor G6 K08463|1|0.0|2132|mmu:215798|G protein-coupled receptor 126 GO:0031224//intrinsic component of membrane;GO:0044464 GO:0004888//transmembrane signaling receptor activity GO:0007186//G-protein coupled receptor signaling pathway gi|50428577|ref|NP_001002268.1|/0/G-protein coupled receptor 126 precursor [Mus musculus] 71545 1047 0.15 0.19 0.341036918 Up 0.126979202 9030625G05Rik RIKEN cDNA 9030625G05 gene - - - - gi|148677562|gb|EDL09509.1|/1.09069e-27/mCG1033558 [Mus musculus] 70988 1094 0.136666667 0.173333333 0.342887714 Up 0.126979202 4931428L18Rik RIKEN cDNA 4931428L18 gene - - GO:0016211 GO:0006541//glutamine metabolic process "gi|148682479|gb|EDL14426.1|/6.19151e-53/RIKEN cDNA 4931428L18, isoform CRA_a [Mus musculus]" 56030 6563 13.34 13.64 0.032084978 Up 0.126922788 Tmem131 transmembrane protein 131 - - - - gi|119372306|ref|NP_061360.2|/0/transmembrane protein 131 [Mus musculus] 107829 2235 12.87666667 13.17666667 0.033226278 Up 0.126922788 Thoc5 THO complex 5 K13174|1|0.0|1342|mmu:107829|THO complex subunit 5 GO:0005856//cytoskeleton;GO:0031981//nuclear lumen;GO:0000346//transcription export complex GO:0003676//nucleic acid binding GO:0006396//RNA processing;GO:0035162//embryonic hemopoiesis;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0006406//mRNA export from nucleus gi|27369587|ref|NP_766026.1|/0/THO complex subunit 5 homolog [Mus musculus] 14461 3258 15.80333333 15.5 -0.027960677 Down 0.126922788 Gata2 GATA binding protein 2 K17894|1|0.0|873|mmu:14461|GATA-binding protein 2 GO:0031981//nuclear lumen;GO:0032991//macromolecular complex "GO:0019904//protein domain specific binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0046914//transition metal ion binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding" GO:0021700//developmental maturation;GO:0030219//megakaryocyte differentiation;GO:0001894//tissue homeostasis;GO:0001701//in utero embryonic development;GO:0042471//ear morphogenesis;GO:0030222//eosinophil differentiation;GO:0021536//diencephalon development;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0045444//fat cell differentiation;GO:0007219//Notch signaling pathway;GO:0007599//hemostasis;GO:0048839//inner ear development;GO:0021953//central nervous system neuron differentiation;GO:0045165//cell fate commitment;GO:0016573//histone acetylation;GO:0008285//negative regulation of cell proliferation;GO:0021515//cell differentiation in spinal cord;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0030218//erythrocyte differentiation;GO:0019827//stem cell population maintenance;GO:0006909//phagocytosis gi|226530726|ref|NP_032116.4|/0/endothelial transcription factor GATA-2 [Mus musculus] 19211 8229 13.44 13.14333333 -0.032201928 Down 0.126922788 Pten phosphatase and tensin homolog "K01110|1|0.0|887|hgl:101714930|phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]" - - - "gi|880854222|ref|XP_005063745.2|/0/PREDICTED: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, partial [Mesocricetus auratus]" 68226 2551 13.14 12.84333333 -0.03294559 Down 0.126922788 Efcab2 EF-hand calcium binding domain 2 K02183|1|3e-19|100|umr:103657204|calmodulin - GO:0046872//metal ion binding - gi|13386110|ref|NP_080902.1|/4.08705e-87/EF-hand calcium-binding domain-containing protein 2 [Mus musculus] 16549 4001 16.33666667 16.64 0.026541787 Up 0.126922788 Khsrp KH-type splicing regulatory protein K13210|1|0.0|941|mmu:16549|far upstream element-binding protein - - - "gi|148706278|gb|EDL38225.1|/0/mCG140911, isoform CRA_b, partial [Mus musculus]" 27274 2494 0.343333333 0.396666667 0.208317236 Up 0.126875776 Zfp354b zinc finger protein 354B K09228|1|0.0|1254|mmu:27274|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|7305545|ref|NP_038772.1|/0/zinc finger protein 354B [Mus musculus] 238722 1629 0.363333333 0.313333333 -0.213595473 Down 0.126875776 Zfp72 zinc finger protein 72 K09228|1|0.0|688|cge:100755363|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|568983357|ref|XP_006517311.1|/0/PREDICTED: zinc finger protein 72 isoform X2 [Mus musculus] 52033 1663 0.323333333 0.373333333 0.20744208 Up 0.126875776 Pbk PDZ binding kinase K08865|1|0.0|645|mmu:52033|PDZ-binding kinase [EC:2.7.12.2] - - - - 16408 5219.57 0.346666667 0.4 0.206450877 Up 0.126875776 Itgal integrin alpha L K05718|1|0.0|2193|mmu:16408|integrin alpha L GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane GO:0043169//cation binding;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0046983//protein dimerization activity GO:0016337//single organismal cell-cell adhesion;GO:0002286//T cell activation involved in immune response;GO:0007166//cell surface receptor signaling pathway;GO:0042098//T cell proliferation;GO:0019722//calcium-mediated signaling;GO:0016337//single organismal cell-cell adhesion;GO:0002286//T cell activation involved in immune response;GO:0007166//cell surface receptor signaling pathway;GO:0042098//T cell proliferation;GO:0019722//calcium-mediated signaling;GO:0016337//single organismal cell-cell adhesion;GO:0002286//T cell activation involved in immune response;GO:0007166//cell surface receptor signaling pathway;GO:0042098//T cell proliferation;GO:0019722//calcium-mediated signaling;GO:0016337//single organismal cell-cell adhesion;GO:0002286//T cell activation involved in immune response;GO:0007166//cell surface receptor signaling pathway;GO:0042098//T cell proliferation;GO:0019722//calcium-mediated signaling gi|359751460|ref|NP_001240803.1|/0/integrin alpha-L isoform 4 precursor [Mus musculus] 17175 3061 1.23 1.306666667 0.087232838 Up 0.126847569 Masp2 mannan-binding lectin serine peptidase 2 K03993|1|1e-107|391|mmu:17175|mannan-binding lectin serine protease 2 [EC:3.4.21.104] - GO:0046872//metal ion binding;GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004175//endopeptidase activity;GO:0005515//protein binding GO:0019538//protein metabolic process;GO:0006952//defense response;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0019538//protein metabolic process;GO:0006952//defense response;GO:0002455//humoral immune response mediated by circulating immunoglobulin gi|54112422|ref|NP_001003893.1|/0/mannan-binding lectin serine protease 2 isoform 1 precursor [Mus musculus] 18861 3273 1.266666667 1.346666667 0.088355874 Up 0.126847569 Pms2 postmeiotic segregation increased 2 (S. cerevisiae) K10858|1|0.0|1680|mmu:18861|DNA mismatch repair protein PMS2 GO:0032300//mismatch repair complex;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0032135//DNA insertion or deletion binding;GO:0004518//nuclease activity GO:0006281//DNA repair;GO:0002566//somatic diversification of immune receptors via somatic mutation;GO:0022403;GO:0002562 gi|121583910|ref|NP_032912.2|/0/mismatch repair endonuclease PMS2 [Mus musculus] 218268 1757 1.266666667 1.19 -0.090075344 Down 0.126847569 Eif4e1b eukaryotic translation initiation factor 4E family member 1B K03259|1|2e-126|455|mmu:218268|translation initiation factor 4E GO:0044424;GO:0044424;GO:0044424;GO:0034518//RNA cap binding complex;GO:0044424;GO:0034518//RNA cap binding complex;GO:0044424;GO:0044424;GO:0034518//RNA cap binding complex;GO:0044424 "GO:0008135//translation factor activity, RNA binding;GO:0008135//translation factor activity, RNA binding;GO:0008135//translation factor activity, RNA binding;GO:0008135//translation factor activity, RNA binding;GO:0008135//translation factor activity, RNA binding;GO:0008135//translation factor activity, RNA binding;GO:0008135//translation factor activity, RNA binding" GO:0006412//translation;GO:0006412//translation;GO:0006412//translation;GO:0006412//translation;GO:0006412//translation;GO:0006412//translation;GO:0006412//translation gi|555290071|ref|NP_001273107.1|/7.93474e-127/eukaryotic translation initiation factor 4E type 1B isoform 3 [Mus musculus] 613254 389 1.246666667 1.17 -0.09156724 Down 0.126847569 AA465934 expressed sequence AA465934 - - - - - 26410 2507 1.286666667 1.366666667 0.087023062 Up 0.126847569 Map3k8 mitogen-activated protein kinase kinase kinase 8 K04415|1|0.0|949|mmu:26410|mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25] GO:0044444//cytoplasmic part GO:0032550;GO:0046872//metal ion binding;GO:0004702//receptor signaling protein serine/threonine kinase activity GO:0006468//protein phosphorylation;GO:0031294//lymphocyte costimulation gi|6678798|ref|NP_031772.1|/0/mitogen-activated protein kinase kinase kinase 8 [Mus musculus] 74729 1617 1.383333333 1.303333333 -0.085942729 Down 0.126847569 Setmar SET domain without mariner transposase fusion K11433|1|2e-175|618|mmu:74729|histone-lysine N-methyltransferase SETMAR [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043229//intracellular organelle GO:0046914//transition metal ion binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0004518//nuclease activity "GO:0007050//cell cycle arrest;GO:0006310//DNA recombination;GO:0010639;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0000738//DNA catabolic process, exonucleolytic" gi|241982732|ref|NP_848478.2|/2.54593e-167/histone-lysine N-methyltransferase SETMAR isoform 1 [Mus musculus] 76872 3912 0.193333333 0.153333333 -0.334419039 Down 0.126819361 Ccdc116 coiled-coil domain containing 116 - - - - gi|257196215|ref|NP_084055.2|/0/coiled-coil domain-containing protein 116 [Mus musculus] 382018 7983 0.216666667 0.173333333 -0.321928095 Down 0.126819361 Unc13a unc-13 homolog A (C. elegans) K15293|1|0.0|3163|mmu:382018|protein unc-13 A/B/C GO:0032991//macromolecular complex;GO:0097060//synaptic membrane;GO:0044424;GO:0042995//cell projection GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0019905//syntaxin binding GO:0007270//neuron-neuron synaptic transmission;GO:0048741//skeletal muscle fiber development;GO:0048168//regulation of neuronal synaptic plasticity;GO:0006904//vesicle docking involved in exocytosis;GO:0006518//peptide metabolic process;GO:0016050//vesicle organization;GO:0007165//signal transduction;GO:0021675//nerve development;GO:0016079//synaptic vesicle exocytosis gi|283837783|ref|NP_001025044.2|/0/protein unc-13 homolog A [Mus musculus] 328287 5099 0.156666667 0.196666667 0.328054198 Up 0.126819361 Gm20554 "predicted gene, 20554" - - - - - 22351 2915 0.156666667 0.196666667 0.328054198 Up 0.126819361 Vill villin-like K05761|1|0.0|763|fab:101815837|villin 1 - - GO:0030835//negative regulation of actin filament depolymerization;GO:0030835//negative regulation of actin filament depolymerization gi|257096031|ref|NP_001158039.1|/0/villin-like protein isoform 1 [Mus musculus] 13421 3702 0.173333333 0.216666667 0.321928095 Up 0.126819361 Dnase1l3 deoxyribonuclease 1-like 3 K11995|1|2e-171|606|mmu:13421|deoxyribonuclease-1-like protein [EC:3.1.21.-] GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0004520//endodeoxyribonuclease activity "GO:0012501//programmed cell death;GO:0000737//DNA catabolic process, endonucleolytic" gi|84490435|ref|NP_031896.3|/1.55465e-170/deoxyribonuclease gamma precursor [Mus musculus] 268958 2575 0.193333333 0.153333333 -0.334419039 Down 0.126819361 Capn11 calpain 11 K08580|1|0.0|1492|mmu:268958|calpain-11 [EC:3.4.22.-] GO:0030141//secretory granule GO:0046872//metal ion binding;GO:0004197//cysteine-type endopeptidase activity GO:0019538//protein metabolic process gi|62000644|ref|NP_001013789.1|/0/calpain-11 [Mus musculus] 16977 1458 0.203333333 0.163333333 -0.316027493 Down 0.126819361 Lrrc23 leucine rich repeat containing 23 "K14696|1|2e-28|129|smm:Smp_162450|solute carrier family 30 (zinc transporter), member 9;K17550|2|5e-22|108|cbr:CBG03304|protein phosphatase 1 regulatory subunit 7" - - - gi|568940908|ref|XP_006505721.1|/5.18179e-168/PREDICTED: leucine-rich repeat-containing protein 23 isoform X2 [Mus musculus] 73893 1285 0.193333333 0.153333333 -0.334419039 Down 0.126819361 Tmem202 transmembrane protein 202 - GO:0031224//intrinsic component of membrane - - gi|30409994|ref|NP_848475.1|/1.64904e-143/transmembrane protein 202 [Mus musculus] 210146 6159 6.903333333 7.073333333 0.035097103 Up 0.126715935 Irgq "immunity-related GTPase family, Q" - - - - "gi|148692383|gb|EDL24330.1|/0/immunity-related GTPase family, Q, isoform CRA_a, partial [Mus musculus]" 224481 1360 6.95 6.783333333 -0.035018589 Down 0.126715935 Tfb1m "transcription factor B1, mitochondrial" "K15266|1|0.0|678|mmu:224481|dimethyladenosine transferase 1, mitochondrial [EC:2.1.1.-]" GO:0005759//mitochondrial matrix GO:0008649//rRNA methyltransferase activity;GO:0008170//N-methyltransferase activity;GO:0003676//nucleic acid binding "GO:0042254//ribosome biogenesis;GO:0006351//transcription, DNA-templated" "gi|22122569|ref|NP_666186.1|/0/dimethyladenosine transferase 1, mitochondrial [Mus musculus]" 70097 7183 5.853333333 5.686666667 -0.041675198 Down 0.126715935 Sash1 SAM and SH3 domain containing 1 - - - - gi|112821670|ref|NP_780364.3|/0/SAM and SH3 domain-containing protein 1 [Mus musculus] 72947 1896 6.036666667 5.87 -0.040391637 Down 0.126715935 Phykpl 5-phosphohydroxy-L-lysine phospholyase K18202|1|0.0|921|mmu:72947|5-phosphonooxy-L-lysine phospho-lyase [EC:4.2.3.134] GO:0043231//intracellular membrane-bounded organelle "GO:0016769//transferase activity, transferring nitrogenous groups;GO:0043168//anion binding" - gi|28077015|ref|NP_082674.1|/0/5-phosphohydroxy-L-lysine phospho-lyase [Mus musculus] 228545 4054 5.996666667 6.17 0.041109709 Up 0.126715935 Vps18 VPS18 CORVET/HOPS core subunit K20181|1|0.0|1909|mmu:228545|vacuolar protein sorting-associated protein 18 GO:0005768//endosome;GO:0000323//lytic vacuole;GO:0005774//vacuolar membrane;GO:0015629//actin cytoskeleton GO:0043169//cation binding;GO:0008092//cytoskeletal protein binding GO:0007033//vacuole organization;GO:0015031//protein transport gi|254675217|ref|NP_758473.3|/0/vacuolar protein sorting-associated protein 18 homolog [Mus musculus] 217258 5629 5.5 5.666666667 0.043068722 Up 0.126715935 Abca8a "ATP-binding cassette, sub-family A (ABC1), member 8a" "K05650|1|0.0|2972|mmu:217258|ATP-binding cassette, subfamily A (ABC1), member 8" GO:0031224//intrinsic component of membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0051234//establishment of localization gi|568973397|ref|XP_006533124.1|/0/PREDICTED: ATP-binding cassette sub-family A member 8-A isoform X2 [Mus musculus] 14450 3329 14.77333333 15.06 0.027726389 Up 0.126518485 Gart phosphoribosylglycinamide formyltransferase K11787|1|0.0|1916|mmu:14450|phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1] GO:0044424 "GO:0016882//cyclo-ligase activity;GO:0032550;GO:0016742//hydroxymethyl-, formyl- and related transferase activity;GO:0043169//cation binding" GO:0042221//response to chemical;GO:0006767//water-soluble vitamin metabolic process;GO:0009396//folic acid-containing compound biosynthetic process;GO:0006188//IMP biosynthetic process;GO:0006144//purine nucleobase metabolic process;GO:0021543//pallium development;GO:0009069//serine family amino acid metabolic process;GO:0022037//metencephalon development gi|93102415|ref|NP_034386.2|/0/trifunctional purine biosynthetic protein adenosine-3 [Mus musculus] 18226 3746 13.36666667 13.65333333 0.030613479 Up 0.126518485 Nup62 nucleoporin 62 K14306|1|4e-139|498|mmu:18226|nuclear pore complex protein Nup62 - - - - 51797 2726 13.66 13.36666667 -0.031317748 Down 0.126518485 Ctps cytidine 5'-triphosphate synthase K01937|1|0.0|1090|cge:100689101|CTP synthase [EC:6.3.4.2] - "GO:0032550;GO:0016879//ligase activity, forming carbon-nitrogen bonds" GO:0009209;GO:0006220//pyrimidine nucleotide metabolic process;GO:0009064//glutamine family amino acid metabolic process gi|625196919|ref|XP_007640658.1|/0/PREDICTED: CTP synthase 1 isoform X1 [Cricetulus griseus] 74498 3483 12.87333333 13.16 0.031773826 Up 0.126518485 Gorasp1 golgi reassembly stacking protein 1 - GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - GO:0045184//establishment of protein localization;GO:0007067//mitotic nuclear division "gi|148677250|gb|EDL09197.1|/0/golgi reassembly stacking protein 1, isoform CRA_a, partial [Mus musculus]" 68083 1753 16.24 15.95 -0.025995209 Down 0.126518485 Pak1ip1 PAK1 interacting protein 1 K14830|1|0.0|781|mmu:68083|protein MAK11 GO:0016020//membrane;GO:0031981//nuclear lumen - GO:0007165//signal transduction gi|17529977|gb|AAL40652.1|AF386076_1/0/p21-activated protein kinase-interacting protein 1 [Mus musculus] 22646 2004 0.89 0.823333333 -0.1123287 Down 0.126471473 Zfp105 zinc finger protein 105 K09228|1|0.0|874|ecb:100630888|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0048232//male gamete generation;GO:0032526//response to retinoic acid;GO:0006351//transcription, DNA-templated" gi|113374173|ref|NP_033570.2|/0/zinc finger protein 35 [Mus musculus] 68074 2439 0.933333333 0.866666667 -0.106915204 Down 0.126471473 A930013F10Rik RIKEN cDNA A930013F10 gene - - - - "gi|148700937|gb|EDL32884.1|/2.78908e-61/mCG145511, partial [Mus musculus]" 12614 11050 0.99 0.92 -0.105794664 Down 0.126471473 Celsr1 "cadherin, EGF LAG seven-pass G-type receptor 1" K04600|1|0.0|5481|mmu:12614|cadherin EGF LAG seven-pass G-type receptor 1 - - - - 110784 4087 0.943333333 0.873333333 -0.111235241 Down 0.126471473 Nr3c2 "nuclear receptor subfamily 3, group C, member 2" K08555|1|0.0|1732|mmu:110784|mineralocorticoid receptor GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0046914//transition metal ion binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0008289//lipid binding;GO:0043566//structure-specific DNA binding" "GO:0006351//transcription, DNA-templated;GO:0009755//hormone-mediated signaling pathway;GO:0008283//cell proliferation;GO:0031958;GO:0006875//cellular metal ion homeostasis;GO:0003008" gi|144227212|ref|NP_001077375.1|/0/mineralocorticoid receptor [Mus musculus] 27276 1925.2 1 0.926666667 -0.109877618 Down 0.126471473 Plekhb1 "pleckstrin homology domain containing, family B (evectins) member 1" - GO:0031513//nonmotile primary cilium;GO:0031224//intrinsic component of membrane;GO:0031513//nonmotile primary cilium;GO:0031224//intrinsic component of membrane;GO:0031513//nonmotile primary cilium;GO:0031224//intrinsic component of membrane;GO:0031513//nonmotile primary cilium;GO:0031224//intrinsic component of membrane;GO:0031513//nonmotile primary cilium;GO:0031224//intrinsic component of membrane;GO:0031513//nonmotile primary cilium;GO:0031224//intrinsic component of membrane;GO:0031513//nonmotile primary cilium;GO:0031224//intrinsic component of membrane;GO:0031513//nonmotile primary cilium;GO:0031224//intrinsic component of membrane GO:0042802//identical protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0060089;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0008289//lipid binding GO:0032502//developmental process;GO:0030154//cell differentiation;GO:0007165//signal transduction;GO:0032502//developmental process;GO:0032502//developmental process;GO:0032502//developmental process;GO:0032502//developmental process;GO:0032502//developmental process;GO:0032502//developmental process gi|533129791|ref|XP_005379999.1|/1.37401e-129/PREDICTED: pleckstrin homology domain-containing family B member 1 isoform X1 [Chinchilla lanigera] 217366 2476 3.793333333 3.666666667 -0.048997034 Down 0.126405656 Lrrc45 leucine rich repeat containing 45 K12175|1|0.0|641|myb:102249210|COP9 signalosome complex subunit 1;K18626|2|6e-14|82.4|myd:102770051|trichohyalin GO:0005815//microtubule organizing center - - gi|564375702|ref|XP_006247986.1|/0/PREDICTED: leucine-rich repeat-containing protein 45 isoform X1 [Rattus norvegicus] 70829 7272 2.483333333 2.59 0.060674173 Up 0.126405656 Ccdc93 coiled-coil domain containing 93 K20478|1|3e-07|61.6|ola:101162333|golgin subfamily B member 1;K10352|3|6e-07|60.8|bom:102264614|myosin heavy chain - - - "gi|148707840|gb|EDL39787.1|/0/coiled-coil domain containing 93, isoform CRA_b, partial [Mus musculus]" 15512 2595 3.38 3.506666667 0.053077052 Up 0.126405656 Hspa2 heat shock protein 2 K03283|1|0.0|1139|mmu:15512|heat shock 70kDa protein 1/8 GO:0043073//germ cell nucleus;GO:0000794//condensed nuclear chromosome;GO:0005891//voltage-gated calcium channel complex;GO:0043073//germ cell nucleus;GO:0000794//condensed nuclear chromosome;GO:0005891//voltage-gated calcium channel complex GO:0032550;GO:0008289//lipid binding;GO:0032550;GO:0008289//lipid binding GO:0007127//meiosis I;GO:0031660//regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle;GO:0022411;GO:0050896//response to stimulus;GO:0007281//germ cell development;GO:0007127//meiosis I;GO:0031660//regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle;GO:0022411;GO:0050896//response to stimulus;GO:0007281//germ cell development gi|880895163|ref|XP_012970791.1|/0/PREDICTED: heat shock-related 70 kDa protein 2 [Mesocricetus auratus] 209630 5995.26 3.853333333 3.98 0.046661439 Up 0.126405656 Frmd4a FERM domain containing 4A K05763|1|3e-35|154|ola:101173478|moesin;K05762|2|1e-34|152|xma:102227279|radixin - - - gi|295389922|ref|NP_766063.3|/0/FERM domain-containing protein 4A isoform 1 [Mus musculus] 56794 2618 2.963333333 2.85 -0.056258999 Down 0.126405656 Hacl1 2-hydroxyacyl-CoA lyase 1 K12261|1|0.0|1148|mmu:56794|2-hydroxyacyl-CoA lyase 1 [EC:4.1.-.-] GO:0042579//microbody GO:0019842//vitamin binding;GO:0043169//cation binding;GO:0016829//lyase activity;GO:0005515//protein binding GO:0009062//fatty acid catabolic process;GO:0006461//protein complex assembly "gi|148692868|gb|EDL24815.1|/0/2-hydroxyacyl-CoA lyase 1, partial [Mus musculus]" 216853 1896 3.923333333 4.05 0.045841993 Up 0.126405656 Wrap53 "WD repeat containing, antisense to Trp53" K16745|1|3e-61|238|der:Dere_GG23638|B9 domain-containing protein 2;K15361|3|2e-30|136|tsp:Tsp_10938|WD repeat-containing protein 48;K03130|4|2e-14|83.6|chx:102176868|transcription initiation factor TFIID subunit 5 GO:0016604//nuclear body;GO:0030529//intracellular ribonucleoprotein complex GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process;GO:0051347//positive regulation of transferase activity gi|21450205|ref|NP_659073.1|/0/telomerase Cajal body protein 1 [Mus musculus] 11736 8034 3.75 3.623333333 -0.049573061 Down 0.126405656 Ankfy1 ankyrin repeat and FYVE domain containing 1 K20129|1|0.0|2216|mmu:11736|rabankyrin-5 GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding GO:0016192//vesicle-mediated transport gi|85702366|ref|NP_033801.4|/0/rabankyrin-5 [Mus musculus] 68867 3556 3.693333333 3.826666667 0.051164761 Up 0.126405656 Rnf122 ring finger protein 122 K15699|1|8e-89|331|mmu:68867|RING finger protein 122 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - "gi|148700833|gb|EDL32780.1|/5.0212e-110/ring finger protein 122, isoform CRA_b, partial [Mus musculus]" 72572 2075 3.8 3.926666667 0.047305715 Up 0.126405656 Spats2 "spermatogenesis associated, serine-rich 2" - GO:0044424 - - "gi|148672194|gb|EDL04141.1|/0/spermatogenesis associated, serine-rich 2, isoform CRA_a, partial [Mus musculus]" 72096 1097 2.773333333 2.663333333 -0.058388025 Down 0.126405656 Mettl10 methyltransferase like 10 - - - - - 74111 4008 4.046666667 3.92 -0.045880361 Down 0.126405656 Rbm19 RNA binding motif protein 19 K14787|1|0.0|1643|mmu:74111|multiple RNA-binding domain-containing protein 1 GO:0043232;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0036094//small molecule binding GO:0009790//embryo development gi|30794154|ref|NP_083038.1|/0/probable RNA-binding protein 19 [Mus musculus] 18974 1695 0.54 0.596666667 0.143965774 Up 0.126321035 Pole2 "polymerase (DNA directed), epsilon 2 (p59 subunit)" K02325|1|0.0|1069|mmu:18974|DNA polymerase epsilon subunit 2 [EC:2.7.7.7] - - - gi|33468927|ref|NP_035263.1|/0/DNA polymerase epsilon subunit 2 [Mus musculus] 100040792 677 0.7 0.636666667 -0.13681669 Down 0.126321035 Gm11627 predicted gene 11627 - - - - "gi|148702192|gb|EDL34139.1|/8.3978e-25/mCG21374, isoform CRA_a [Mus musculus]" 74464 5397 0.573333333 0.63 0.13597767 Up 0.126321035 Zswim5 zinc finger SWIM-type containing 5 - - - - gi|28972770|dbj|BAC65801.1|/0/mKIAA1511 protein [Mus musculus] 74246 1537 0.543333333 0.6 0.143124942 Up 0.126321035 Gale "galactose-4-epimerase, UDP" K01784|1|0.0|707|mmu:74246|UDP-glucose 4-epimerase [EC:5.1.3.2] - "GO:0042802//identical protein binding;GO:0036094//small molecule binding;GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0048037//cofactor binding" GO:0006012//galactose metabolic process "gi|148698014|gb|EDL29961.1|/0/galactose-4-epimerase, UDP, isoform CRA_b, partial [Mus musculus]" 72821 4562 0.393333333 0.343333333 -0.196142522 Down 0.126132987 Scn2b "sodium channel, voltage-gated, type II, beta" K04846|1|6e-105|385|mmu:72821|voltage-gated sodium channel type II beta GO:0005887//integral component of plasma membrane GO:0005488//binding;GO:0016247//channel regulator activity;GO:0005248//voltage-gated sodium channel activity GO:0002027//regulation of heart rate;GO:0006941//striated muscle contraction;GO:0048731//system development;GO:0003254//regulation of membrane depolarization;GO:0002028//regulation of sodium ion transport;GO:0017085//response to insecticide;GO:0086001//cardiac muscle cell action potential;GO:0034220//ion transmembrane transport gi|472391630|ref|XP_004415103.1|/1.92571e-109/PREDICTED: sodium channel subunit beta-2 [Odobenus rosmarus divergens] 233020 2415 0.406666667 0.353333333 -0.202816883 Down 0.126132987 Hipk4 homeodomain interacting protein kinase 4 K08826|1|0.0|1194|mmu:233020|homeodomain interacting protein kinase [EC:2.7.11.1] GO:0044424 GO:0004672//protein kinase activity;GO:0032550 GO:0006464//cellular protein modification process gi|161333817|ref|NP_001028487.2|/0/homeodomain-interacting protein kinase 4 [Mus musculus] 70393 1504 0.306666667 0.353333333 0.204358499 Up 0.126132987 2210416O15Rik RIKEN cDNA 2210416O15 gene "K19719|1|3e-07|59.3|aga:AgaP_AGAP011620|collagen, type II, alpha;K16628|2|1e-06|57.4|cjc:100385760|collagen, type VII, alpha;K06236|3|1e-06|57.0|xla:380515|collagen, type I, alpha;K19720|4|1e-06|57.0|mdo:100028423|collagen, type III, alpha" - - - gi|823392689|ref|XP_012411404.1|/1.81888e-14/PREDICTED: collagen alpha-1(I) chain-like [Trichechus manatus latirostris] 56643 3123 0.41 0.356666667 -0.201047519 Down 0.126132987 Slc15a1 "solute carrier family 15 (oligopeptide transporter), member 1" "K14206|1|0.0|1367|mmu:56643|solute carrier family 15 (oligopeptide transporter), member 1" GO:0031224//intrinsic component of membrane GO:0015322;GO:0016247//channel regulator activity GO:0006857//oligopeptide transport;GO:0045184//establishment of protein localization;GO:0006865//amino acid transport gi|119392092|ref|NP_444309.2|/0/solute carrier family 15 member 1 [Mus musculus] 103149 3042 0.35 0.403333333 0.20461772 Up 0.126132987 Upb1 "ureidopropionase, beta" K01431|1|0.0|811|mmu:103149|beta-ureidopropionase [EC:3.5.1.6] GO:0044424 "GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0046914//transition metal ion binding" GO:0008652//cellular amino acid biosynthetic process;GO:0007275//multicellular organism development gi|19527212|ref|NP_598756.1|/0/beta-ureidopropionase [Mus musculus] 109624 4035 12.48 12.19666667 -0.033131019 Down 0.126076573 Cald1 caldesmon 1 K12327|1|1e-93|347|mmu:109624|caldesmon GO:0044297//cell body;GO:0030864//cortical actin cytoskeleton;GO:0044327//dendritic spine head;GO:0016020//membrane GO:0008092//cytoskeletal protein binding GO:0044703;GO:0043393//regulation of protein binding;GO:0007015//actin filament organization;GO:0006937//regulation of muscle contraction gi|564346265|ref|XP_006236322.1|/1.16566e-110/PREDICTED: non-muscle caldesmon isoform X1 [Rattus norvegicus] 67789 1737 14.65333333 14.93 0.02698528 Up 0.126076573 Dalrd3 DALR anticodon binding domain containing 3 - GO:0044424 GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550 GO:0006418//tRNA aminoacylation for protein translation gi|110611931|ref|NP_080654.3|/0/DALR anticodon-binding domain-containing protein 3 [Mus musculus] 71990 3956 13.96333333 13.68333333 -0.029223662 Down 0.126076573 Ddx54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 K14808|1|0.0|1541|mmu:71990|ATP-dependent RNA helicase DDX54/DBP10 [EC:3.6.4.13] GO:0031981//nuclear lumen "GO:0032550;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0035258//steroid hormone receptor binding;GO:0003724//RNA helicase activity" "GO:0006351//transcription, DNA-templated" gi|28076989|ref|NP_082317.1|/0/ATP-dependent RNA helicase DDX54 [Mus musculus] 76650 2828 12.05333333 11.77333333 -0.033909335 Down 0.126076573 Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) K12260|1|8e-55|218|mmu:76650|sulfiredoxin [EC:1.8.98.2] GO:0044444//cytoplasmic part GO:0016209//antioxidant activity;GO:0016491//oxidoreductase activity;GO:0003676//nucleic acid binding;GO:0032550 GO:0006950//response to stress;GO:0044710 gi|402747081|ref|NP_083964.2|/6.71367e-54/sulfiredoxin-1 [Mus musculus] 76299 2647 14.10666667 14.38666667 0.028355237 Up 0.126076573 Erp44 endoplasmic reticulum protein 44 K17264|1|0.0|785|mmu:76299|endoplasmic reticulum resident protein 44 GO:0044432;GO:0031090//organelle membrane "GO:0016862//intramolecular oxidoreductase activity, interconverting keto- and enol-groups;GO:0005488//binding" GO:0044267//cellular protein metabolic process;GO:0035966//response to topologically incorrect protein;GO:0019725//cellular homeostasis gi|50510531|dbj|BAD32251.1|/0/mKIAA0573 protein [Mus musculus] 433759 1971 15.07666667 15.34666667 0.025607838 Up 0.125766294 Hdac1 histone deacetylase 1 K06067|1|0.0|819|oas:100820752|histone deacetylase 1/2 [EC:3.5.1.98] GO:0070822//Sin3-type complex;GO:0044444//cytoplasmic part;GO:0044297//cell body GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0044212//transcription regulatory region DNA binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0017136//NAD-dependent histone deacetylase activity;GO:0019899//enzyme binding GO:0030326//embryonic limb morphogenesis;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0030521//androgen receptor signaling pathway;GO:0045687//positive regulation of glial cell differentiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0021543//pallium development;GO:0051726//regulation of cell cycle;GO:0001942//hair follicle development;GO:0042476//odontogenesis;GO:0006979//response to oxidative stress;GO:0010830//regulation of myotube differentiation;GO:0016575//histone deacetylation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0007599//hemostasis;GO:0030178//negative regulation of Wnt signaling pathway;GO:0043010//camera-type eye development;GO:0042221//response to chemical;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0032897//negative regulation of viral transcription gi|82697313|ref|NP_001032521.1|/0/histone deacetylase 1 [Bos taurus] 231050 2541 11.28666667 11.01666667 -0.034931702 Down 0.125766294 Galnt11 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 K00710|1|0.0|1268|mmu:231050|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008376//acetylgalactosaminyltransferase activity GO:0006464//cellular protein modification process gi|21450297|ref|NP_659157.1|/0/polypeptide N-acetylgalactosaminyltransferase 11 [Mus musculus] 23917 2471.83 15.17333333 15.44333333 0.025446125 Up 0.125766294 Impdh1 inosine 5'-phosphate dehydrogenase 1 K00088|1|0.0|1008|mmu:23917|IMP dehydrogenase [EC:1.1.1.205] GO:0043231//intracellular membrane-bounded organelle "GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0009152//purine ribonucleotide biosynthetic process;GO:0032943//mononuclear cell proliferation "gi|148681842|gb|EDL13789.1|/0/inosine 5'-phosphate dehydrogenase 1, isoform CRA_b, partial [Mus musculus]" 50908 2920.95 13.44666667 13.18 -0.028898213 Down 0.125766294 C1s1 "complement component 1, s subcomponent 1" "K01331|1|0.0|1386|mmu:50908|complement component 1, s subcomponent [EC:3.4.21.42]" GO:0031012//extracellular matrix;GO:0031012//extracellular matrix GO:0004175//endopeptidase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004175//endopeptidase activity;GO:0046872//metal ion binding;GO:0005515//protein binding GO:0006952//defense response;GO:0046683//response to organophosphorus;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0019538//protein metabolic process;GO:0030154//cell differentiation;GO:0006952//defense response;GO:0046683//response to organophosphorus;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0019538//protein metabolic process;GO:0030154//cell differentiation gi|148277054|ref|NP_659187.2|/0/complement C1s-A subcomponent precursor [Mus musculus] 64296 1985 14.08 13.80666667 -0.028282281 Down 0.125766294 Abhd8 abhydrolase domain containing 8 K13701|1|0.0|744|mmu:64296|abhydrolase domain-containing protein 8 - GO:0003824//catalytic activity - gi|257153457|ref|NP_071864.2|/0/protein ABHD8 [Mus musculus] 328035 1257 0.4 0.35 -0.192645078 Down 0.125728685 Fads6 "fatty acid desaturase domain family, member 6" K12419|1|0.0|665|mmu:328035|fatty acid desaturase 6 [EC:1.14.19.-] GO:0031224//intrinsic component of membrane GO:0003824//catalytic activity GO:0006631//fatty acid metabolic process gi|267844885|ref|NP_828874.3|/0/fatty acid desaturase 6 [Mus musculus] 271813 3462 0.326666667 0.373333333 0.192645078 Up 0.125728685 Agbl2 ATP/GTP binding protein-like 2 K05840|1|2e-19|100|myb:102243447|dopamine receptor D5;K04257|2|4e-14|83.6|shr:100920260|olfactory receptor GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0008235//metalloexopeptidase activity GO:0019538//protein metabolic process gi|160420289|ref|NP_848870.2|/0/cytosolic carboxypeptidase 2 [Mus musculus] 17171 4639 0.33 0.376666667 0.190822342 Up 0.125728685 Mas1 MAS1 oncogene K04303|1|4e-168|595|mmu:17171|MAS1 oncogene - - - - 116939 4649 0.356666667 0.406666667 0.189270351 Up 0.125728685 Pnpla3 patatin-like phospholipase domain containing 3 K13534|1|0.0|785|mmu:116939|patatin-like phospholipase domain-containing protein 3 [EC:3.1.1.3 2.3.1.-] GO:0031224//intrinsic component of membrane GO:0016411//acylglycerol O-acyltransferase activity;GO:0016298//lipase activity;GO:0052689//carboxylic ester hydrolase activity GO:0006641//triglyceride metabolic process gi|144226245|ref|NP_473429.2|/0/patatin-like phospholipase domain-containing protein 3 [Mus musculus] 58172 5575.34 5.41 5.566666667 0.041185103 Up 0.125578247 Sertad2 SERTA domain containing 2 - - GO:0005488//binding;GO:0005488//binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|568970389|ref|XP_006514828.1|/2.8745e-142/PREDICTED: SERTA domain-containing protein 2 isoform X2 [Mus musculus] 74125 4598.86 6.6 6.763333333 0.035268435 Up 0.125578247 Armc8 armadillo repeat containing 8 - - - - gi|260763999|ref|NP_001159610.1|/0/armadillo repeat-containing protein 8 isoform 2 [Mus musculus] 109019 2596.69 5.7 5.856666667 0.039117866 Up 0.125578247 Nabp1 nucleic acid binding protein 1 "K15280|1|2e-26|123|tca:660868|solute carrier family 35, member C2" - - - - 227699 5670 5.853333333 6.013333333 0.038906494 Up 0.125578247 Nup188 nucleoporin 188 K14311|1|0.0|3241|mmu:227699|nuclear pore complex protein Nup188 GO:0005635//nuclear envelope - GO:0050658//RNA transport;GO:0045184//establishment of protein localization gi|37359810|dbj|BAC97883.1|/0/mKIAA0169 protein [Mus musculus] 229715 5574.02 6.296666667 6.136666667 -0.037133075 Down 0.125578247 Amigo1 adhesion molecule with Ig like domain 1 K19511|1|1e-15|87.4|cmy:102931973|peroxidase [EC:1.11.1.7] - - - - 69399 9789 5.78 5.623333333 -0.039643925 Down 0.125578247 1700025G04Rik RIKEN cDNA 1700025G04 gene - - - - gi|37574070|ref|NP_932107.1|/1.49845e-61/uncharacterized protein C1orf21 homolog [Mus musculus] 67842 3828 5.963333333 5.8 -0.040066081 Down 0.125578247 Nop9 NOP9 nucleolar protein K14790|1|0.0|999|mmu:67842|nucleolar protein 9 - - - gi|169646352|ref|NP_080679.3|/0/nucleolar protein 9 [Mus musculus] 235293 2249 5.156666667 5 -0.044510696 Down 0.125578247 Sc5d sterol-C5-desaturase K00227|1|5e-174|613|mmu:235293|Delta7-sterol 5-desaturase [EC:1.14.19.20] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0046996 GO:0006695//cholesterol biosynthetic process;GO:0006631//fatty acid metabolic process gi|27777693|ref|NP_766357.1|/4.18495e-173/lathosterol oxidase [Mus musculus] 101631 2481.18 5.69 5.846666667 0.039185689 Up 0.125578247 Pwwp2b PWWP domain containing 2B K17398|1|4e-09|66.6|lcm:102358591|DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37] - - - gi|109733388|gb|AAI16670.1|/0/PWWP domain containing 2B [Mus musculus] 67471 3057 6.333333333 6.17 -0.037694523 Down 0.125578247 Gpatch1 G patch domain containing 1 K13123|1|0.0|1443|mmu:67471|G patch domain-containing protein 1 GO:0005681//spliceosomal complex GO:0097159//organic cyclic compound binding - gi|13385692|ref|NP_080457.1|/0/G patch domain-containing protein 1 [Mus musculus] 233878 3808.5 5.173333333 5.016666667 -0.044365071 Down 0.125578247 Sez6l2 seizure related 6 homolog like 2 K10362|1|0.0|699|gfr:102036530|myosin XVIII;K17495|2|3e-58|230|myb:102260673|CUB and sushi domain-containing protein GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane - - gi|357588419|ref|NP_001239495.1|/0/seizure 6-like protein 2 isoform 2 precursor [Mus musculus] 14365 12742 0.16 0.196666667 0.297680549 Up 0.125409004 Fzd3 frizzled class receptor 3 K02329|1|0.0|1358|mmu:14365|frizzled 3 - - - - 22137 2711 0.21 0.17 -0.304854582 Down 0.125409004 Ttk Ttk protein kinase K08866|1|0.0|1382|mmu:22137|serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1] - GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0032550;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|568961257|ref|XP_006511122.1|/0/PREDICTED: dual specificity protein kinase TTK isoform X2 [Mus musculus] 100125339 1649 0.206666667 0.166666667 -0.310340121 Down 0.125409004 A230020J21Rik RIKEN cDNA A230020J21 gene "K08220|1|1e-117|426|mmu:226844|MFS transporter, FLVCR family, feline leukemia virus subgroup C receptor-related protein" - - - - 108077 3972 11.73 11.99 0.031628645 Up 0.12531498 Skiv2l superkiller viralicidic activity 2-like (S. cerevisiae) K12599|1|0.0|2274|mmu:108077|antiviral helicase SKI2 [EC:3.6.4.-] GO:0043234//protein complex "GO:0042623//ATPase activity, coupled;GO:0032550" - "gi|148694814|gb|EDL26761.1|/0/mCG15924, isoform CRA_i, partial [Mus musculus]" 19731 3887 10.89 11.15333333 0.034470991 Up 0.12531498 Rgl1 "ral guanine nucleotide dissociation stimulator,-like 1" K17635|1|0.0|1352|mmu:19731|ral guanine nucleotide dissociation stimulator-like 1 GO:0044444//cytoplasmic part GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0006629//lipid metabolic process;GO:0007264//small GTPase mediated signal transduction gi|31543584|ref|NP_058542.2|/0/ral guanine nucleotide dissociation stimulator-like 1 [Mus musculus] 627352 1710 11.46666667 11.73 0.032756949 Up 0.12531498 Morf4l1b mortality factor 4 like 1B K11339|1|0.0|664|mmu:627352|mortality factor 4-like protein 1 - - - - 16998 5209 14.58666667 14.84333333 0.025164874 Up 0.12531498 Ltbp3 latent transforming growth factor beta binding protein 3 K08023|1|0.0|2452|mmu:16998|latent transforming growth factor beta binding protein 2/3/4 - - - gi|124487415|ref|NP_032546.2|/0/latent-transforming growth factor beta-binding protein 3 precursor [Mus musculus] 228714 3622.27 13.30666667 13.56333333 0.02756256 Up 0.12531498 Csrp2bp cysteine and glycine-rich protein 2 binding protein K18188|1|1e-97|360|ola:101162815|protein PET117 - GO:0016407//acetyltransferase activity - gi|262231838|ref|NP_852082.2|/0/cysteine-rich protein 2-binding protein isoform 1 [Mus musculus] 54616 5995 12.56333333 12.82 0.029176968 Up 0.12531498 Extl3 exostoses (multiple)-like 3 "K02370|1|0.0|1857|mmu:54616|alpha-1,4-N-acetylglucosaminyltransferase EXTL3 [EC:2.4.1.223 2.4.1.224]" GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane "GO:0043169//cation binding;GO:0016757//transferase activity, transferring glycosyl groups" GO:0016049//cell growth gi|60360330|dbj|BAD90409.1|/0/mKIAA0519 protein [Mus musculus] 74104 3043 14.08 13.82 -0.026889718 Down 0.12531498 Abcb6 "ATP-binding cassette, sub-family B (MDR/TAP), member 6" "K05661|1|0.0|1568|mmu:74104|ATP-binding cassette, subfamily B (MDR/TAP), member 6" - - - - 242553 4801 0.216666667 0.176666667 -0.294447358 Down 0.125126932 Kank4 KN motif and ankyrin repeat domains 4 K15503|1|4e-15|87.4|aqu:100635111|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B GO:0044424 - GO:0032232//negative regulation of actin filament bundle assembly gi|40254257|ref|NP_766460.2|/0/KN motif and ankyrin repeat domain-containing protein 4 [Mus musculus] 70809 2404 0.163333333 0.2 0.292180751 Up 0.125126932 Clec2g "C-type lectin domain family 2, member g" K10072|1|3e-49|199|cge:100762568|C-type lectin domain family 2 member D - - - - 382111 3874 0.176666667 0.216666667 0.294447358 Up 0.125126932 Susd5 sushi domain containing 5 - - - GO:0022610 gi|160333452|ref|NP_001094980.1|/0/sushi domain-containing protein 5 precursor [Mus musculus] 21684 2725 0.22 0.18 -0.289506617 Down 0.125126932 Tectb tectorin beta K18273|1|5e-17|92.8|xtr:100490936|alpha-tectorin;K19899|5|2e-16|90.5|hgl:101709061|pancreatic secretory granule membrane major glycoprotein GP2 GO:0031224//intrinsic component of membrane;GO:0031012//extracellular matrix GO:0005198//structural molecule activity GO:0050954//sensory perception of mechanical stimulus gi|7363457|ref|NP_033374.2|/0/beta-tectorin precursor [Mus musculus] 66901 2398 0.163333333 0.2 0.292180751 Up 0.125126932 Proz "protein Z, vitamin K-dependent plasma glycoprotein" K01314|1|5e-61|238|cmk:103185526|coagulation factor X [EC:3.4.21.6] GO:0044432;GO:0044431//Golgi apparatus part GO:0046872//metal ion binding;GO:0004175//endopeptidase activity GO:0007599//hemostasis;GO:0018200//peptidyl-glutamic acid modification gi|13385306|ref|NP_080110.1|/0/vitamin K-dependent protein Z precursor [Mus musculus] 330217 3162 0.236666667 0.193333333 -0.291766124 Down 0.125126932 Gal3st4 galactose-3-O-sulfotransferase 4 K09677|1|0.0|904|mmu:330217|galactose-3-O-sulfotransferase 4 [EC:2.8.2.-] - GO:0008146//sulfotransferase activity - gi|84370027|ref|NP_001028588.1|/0/galactose-3-O-sulfotransferase 4 [Mus musculus] 16196 3211 0.166666667 0.203333333 0.286881148 Up 0.125126932 Il7 interleukin 7 K05431|1|2e-75|286|cge:100756443|interleukin 7 - - - - 215928 3264.52 0.96 1.026666667 0.096861539 Up 0.125042311 Mfsd4b5 major facilitator superfamily domain containing 4B5 "K08175|1|3e-57|226|rno:337920|MFS transporter, FHS family, Na+ dependent glucose transporter 1" - - - - 12484 1825 1.026666667 0.96 -0.096861539 Down 0.125042311 Cd24a CD24a antigen K06469|1|9e-14|81.3|mmu:12484|CD24 antigen GO:0009986//cell surface;GO:0031090//organelle membrane;GO:0046658//anchored component of plasma membrane;GO:0005902//microvillus GO:0019900//kinase binding;GO:0030295//protein kinase activator activity GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0033627//cell adhesion mediated by integrin;GO:0044710;GO:0043405//regulation of MAP kinase activity;GO:0007268//chemical synaptic transmission;GO:0007405//neuroblast proliferation;GO:0048870//cell motility;GO:0001783//B cell apoptotic process;GO:0055092//sterol homeostasis;GO:0022409//positive regulation of cell-cell adhesion;GO:0072160//nephron tubule epithelial cell differentiation;GO:0002437//inflammatory response to antigenic stimulus;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0010975//regulation of neuron projection development;GO:0061318;GO:0006897//endocytosis;GO:0030888//regulation of B cell proliferation;GO:0034102;GO:0031334//positive regulation of protein complex assembly;GO:0048545//response to steroid hormone;GO:0072311;GO:0002424;GO:0019722//calcium-mediated signaling;GO:0032595;GO:0001777//T cell homeostatic proliferation;GO:0032907//transforming growth factor beta3 production;GO:0002327//immature B cell differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0032599;GO:0031294//lymphocyte costimulation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0042102//positive regulation of T cell proliferation;GO:0010721//negative regulation of cell development gi|51442|emb|CAA39843.1|/7.38917e-49/HSA-C [Mus musculus] 210622 2855 0.95 1.016666667 0.097847323 Up 0.125042311 Pamr1 peptidase domain containing associated with muscle regeneration 1 K03992|1|4e-46|189|bfo:BRAFLDRAFT_91518|mannan-binding lectin serine protease 1 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|224994201|ref|NP_776110.3|/0/inactive serine protease PAMR1 precursor [Mus musculus] 270163 11974 1.01 0.943333333 -0.098515741 Down 0.125042311 Myo9a myosin IXa K10360|1|0.0|4908|mmu:270163|myosin IX GO:0031224//intrinsic component of membrane;GO:0015629//actin cytoskeleton GO:0008047//enzyme activator activity;GO:0043169//cation binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0007165//signal transduction gi|241896922|ref|NP_766606.2|/0/unconventional myosin-IXa [Mus musculus] 210105 4993 0.676666667 0.74 0.129079949 Up 0.125032908 Zfp719 zinc finger protein 719 K09228|1|0.0|1560|mmu:210105|KRAB domain-containing zinc finger protein - - - gi|255003815|ref|NP_766070.1|/0/zinc finger protein 719 [Mus musculus] 17918 11684 0.68 0.623333333 -0.125530882 Down 0.125032908 Myo5a myosin VA K10357|1|0.0|3571|mmu:17918|myosin V - - - "gi|148694358|gb|EDL26305.1|/0/myosin Va, isoform CRA_a, partial [Mus musculus]" 12829 7808 0.756666667 0.693333333 -0.126108769 Down 0.125032908 Col4a4 "collagen, type IV, alpha 4" "K06237|1|0.0|817|mmu:12829|collagen, type IV, alpha" GO:0044420//extracellular matrix component;GO:0005578//proteinaceous extracellular matrix - - gi|34328045|ref|NP_031761.1|/0/collagen alpha-4(IV) chain precursor [Mus musculus] 211134 1800 0.716666667 0.653333333 -0.133483005 Down 0.125032908 Lzts1 "leucine zipper, putative tumor suppressor 1" - GO:0031981//nuclear lumen;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0044459 GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding GO:0006383//transcription from RNA polymerase III promoter;GO:0010507//negative regulation of autophagy;GO:0010769//regulation of cell morphogenesis involved in differentiation;GO:0050804//modulation of synaptic transmission gi|269784743|ref|NP_955396.2|/0/leucine zipper putative tumor suppressor 1 [Mus musculus] 243937 4411 0.61 0.666666667 0.128156351 Up 0.125032908 Zfp536 zinc finger protein 536 K09228|1|9e-32|142|gja:107115679|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0044212//transcription regulatory region DNA binding;GO:0046914//transition metal ion binding "GO:0009968//negative regulation of signal transduction;GO:0006351//transcription, DNA-templated;GO:0030182//neuron differentiation" gi|27369509|ref|NP_759017.1|/0/zinc finger protein 536 [Mus musculus] 100041677 2729 0.673333333 0.616666667 -0.126830022 Down 0.125032908 Gm13157 zinc finger protein 984 K09228|1|0.0|1191|mmu:100041677|KRAB domain-containing zinc finger protein - - - gi|187608663|ref|NP_001120661.1|/0/uncharacterized protein LOC100041677 [Mus musculus] 75538 849 0.673333333 0.613333333 -0.134649527 Down 0.125032908 Fam71e1 "family with sequence similarity 71, member E1" - - - - gi|564297423|ref|XP_006223323.1|/1.16854e-99/PREDICTED: protein FAM71E1 isoform X1 [Rattus norvegicus] 320662 2534 0.72 0.656666667 -0.132835683 Down 0.125032908 Casc1 cancer susceptibility candidate 1 K17580|1|0.0|1304|mmu:320662|cancer susceptibility candidate protein 1 GO:0005874//microtubule GO:0015631//tubulin binding GO:0006928//movement of cell or subcellular component "gi|148678732|gb|EDL10679.1|/0/cancer susceptibility candidate 1, isoform CRA_d, partial [Mus musculus]" 230761 2882 12.96 13.21333333 0.027928744 Up 0.124873068 Zfp362 zinc finger protein 362 K09228|1|2e-41|173|sko:100371350|KRAB domain-containing zinc finger protein GO:0044464 GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding - gi|124487369|ref|NP_001074567.1|/0/zinc finger protein 362 [Mus musculus] 18033 4128 12.7 12.45 -0.028682755 Down 0.124873068 Nfkb1 "nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105" K02580|1|0.0|1779|mmu:18033|nuclear factor NF-kappa-B p105 subunit GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0001071//nucleic acid binding transcription factor activity;GO:0043566//structure-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0042802//identical protein binding GO:0006954//inflammatory response;GO:0032769//negative regulation of monooxygenase activity;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0010883//regulation of lipid storage;GO:0070555//response to interleukin-1;GO:0006915//apoptotic process;GO:0048534//hematopoietic or lymphoid organ development;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0009612//response to mechanical stimulus;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0050851//antigen receptor-mediated signaling pathway;GO:0010742//macrophage derived foam cell differentiation;GO:0030301//cholesterol transport;GO:0042036//negative regulation of cytokine biosynthetic process;GO:0001819//positive regulation of cytokine production;GO:0010038//response to metal ion;GO:0033619//membrane protein proteolysis;GO:0006366//transcription from RNA polymerase II promoter;GO:0010894//negative regulation of steroid biosynthetic process;GO:0051707//response to other organism gi|117606364|ref|NP_032715.2|/0/nuclear factor NF-kappa-B p105 subunit [Mus musculus] 74270 4157 14.06 14.31333333 0.025763096 Up 0.124873068 Usp20 ubiquitin specific peptidase 20 K11848|1|0.0|1764|mmu:74270|ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12] GO:0044444//cytoplasmic part GO:0016790//thiolester hydrolase activity;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0005102//receptor binding GO:0016192//vesicle-mediated transport;GO:0019941//modification-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0007186//G-protein coupled receptor signaling pathway gi|50510751|dbj|BAD32361.1|/0/mKIAA1003 protein [Mus musculus] 19401 3215.89 11.19 11.43666667 0.031456589 Up 0.124873068 Rara "retinoic acid receptor, alpha" K08527|1|0.0|797|mmu:19401|retinoic acid receptor alpha GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0031981//nuclear lumen;GO:0043005//neuron projection;GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0044297//cell body "GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0030371//translation repressor activity;GO:0003712//transcription cofactor activity;GO:0003729//mRNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003682//chromatin binding;GO:0019901//protein kinase binding;GO:0005501//retinoid binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0019207//kinase regulator activity;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0030371//translation repressor activity;GO:0003712//transcription cofactor activity;GO:0003729//mRNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003682//chromatin binding;GO:0019901//protein kinase binding;GO:0005501//retinoid binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0019207//kinase regulator activity;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0030371//translation repressor activity;GO:0003712//transcription cofactor activity;GO:0003729//mRNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003682//chromatin binding;GO:0019901//protein kinase binding;GO:0005501//retinoid binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0019207//kinase regulator activity;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0030371//translation repressor activity;GO:0003712//transcription cofactor activity;GO:0003729//mRNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003682//chromatin binding;GO:0019901//protein kinase binding;GO:0005501//retinoid binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0019207//kinase regulator activity" GO:0055007//cardiac muscle cell differentiation;GO:0050804//modulation of synaptic transmission;GO:0006915//apoptotic process;GO:0044093;GO:0035295//tube development;GO:0008406//gonad development;GO:0048232//male gamete generation;GO:0045064//T-helper 2 cell differentiation;GO:0021543//pallium development;GO:0051726//regulation of cell cycle;GO:0042552//myelination;GO:0043410//positive regulation of MAPK cascade;GO:0006413//translational initiation;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0001819//positive regulation of cytokine production;GO:0043550//regulation of lipid kinase activity;GO:0030182//neuron differentiation;GO:0003416//endochondral bone growth;GO:0043627//response to estrogen;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0044703;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006464//cellular protein modification process;GO:0033273//response to vitamin;GO:0001818//negative regulation of cytokine production;GO:0097305//response to alcohol;GO:0001655//urogenital system development;GO:0032526//response to retinoic acid;GO:0032496//response to lipopolysaccharide;GO:0006909//phagocytosis;GO:0055007//cardiac muscle cell differentiation;GO:0050804//modulation of synaptic transmission;GO:0006915//apoptotic process;GO:0044093;GO:0035295//tube development;GO:0008406//gonad development;GO:0048232//male gamete generation;GO:0045064//T-helper 2 cell differentiation;GO:0051726//regulation of cell cycle;GO:0042552//myelination;GO:0043410//positive regulation of MAPK cascade;GO:0006413//translational initiation;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0001819//positive regulation of cytokine production;GO:0030182//neuron differentiation;GO:0003416//endochondral bone growth;GO:0043627//response to estrogen;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0006464//cellular protein modification process;GO:0001818//negative regulation of cytokine production;GO:0097305//response to alcohol;GO:0032526//response to retinoic acid;GO:0032496//response to lipopolysaccharide;GO:0006909//phagocytosis;GO:0055007//cardiac muscle cell differentiation;GO:0050804//modulation of synaptic transmission;GO:0006915//apoptotic process;GO:0044093;GO:0035295//tube development;GO:0008406//gonad development;GO:0048232//male gamete generation;GO:0045064//T-helper 2 cell differentiation;GO:0051726//regulation of cell cycle;GO:0042552//myelination;GO:0043410//positive regulation of MAPK cascade;GO:0006413//translational initiation;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0001819//positive regulation of cytokine production;GO:0030182//neuron differentiation;GO:0003416//endochondral bone growth;GO:0043627//response to estrogen;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0006464//cellular protein modification process;GO:0001818//negative regulation of cytokine production;GO:0097305//response to alcohol;GO:0032526//response to retinoic acid;GO:0032496//response to lipopolysaccharide;GO:0006909//phagocytosis;GO:0055007//cardiac muscle cell differentiation;GO:0050804//modulation of synaptic transmission;GO:0006915//apoptotic process;GO:0044093;GO:0035295//tube development;GO:0008406//gonad development;GO:0048232//male gamete generation;GO:0045064//T-helper 2 cell differentiation;GO:0051726//regulation of cell cycle;GO:0042552//myelination;GO:0043410//positive regulation of MAPK cascade;GO:0006413//translational initiation;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0001819//positive regulation of cytokine production;GO:0030182//neuron differentiation;GO:0003416//endochondral bone growth;GO:0043627//response to estrogen;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0006464//cellular protein modification process;GO:0001818//negative regulation of cytokine production;GO:0097305//response to alcohol;GO:0032526//response to retinoic acid;GO:0032496//response to lipopolysaccharide;GO:0006909//phagocytosis "gi|148684228|gb|EDL16175.1|/0/retinoic acid receptor, alpha [Mus musculus]" 76477 1866 11.05 10.79666667 -0.033460402 Down 0.124873068 Pcolce2 procollagen C-endopeptidase enhancer 2 K14616|1|4e-40|168|crg:105327358|cubilin - - - gi|22095011|ref|NP_083896.1|/0/procollagen C-endopeptidase enhancer 2 precursor [Mus musculus] 72307 1232 12.07 12.31666667 0.029186188 Up 0.124873068 2510002D24Rik RIKEN cDNA 2510002D24 gene - - - - gi|148665120|gb|EDK97536.1|/2.99651e-78/mCG126591 [Mus musculus] 233033 4391 13.29 13.04333333 -0.027028495 Down 0.124873068 Samd4b sterile alpha motif domain containing 4B K05734|1|3e-06|57.8|fch:102047228|p21-activated kinase 4 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated" "gi|148692189|gb|EDL24136.1|/0/sterile alpha motif domain containing 4B, isoform CRA_a, partial [Mus musculus]" 66317 1256.02 12.19 12.44333333 0.029674882 Up 0.124873068 Wdr61 WD repeat domain 61 K12602|1|1e-171|605|cjc:100415315|WD repeat-containing protein 61 GO:0000785//chromatin;GO:0008023//transcription elongation factor complex;GO:0000785//chromatin;GO:0008023//transcription elongation factor complex;GO:0000785//chromatin;GO:0008023//transcription elongation factor complex GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0031062//positive regulation of histone methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0030099//myeloid cell differentiation;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0007166//cell surface receptor signaling pathway;GO:0031062//positive regulation of histone methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0030099//myeloid cell differentiation;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0007166//cell surface receptor signaling pathway;GO:0031062//positive regulation of histone methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0030099//myeloid cell differentiation;GO:0006368//transcription elongation from RNA polymerase II promoter "gi|148693879|gb|EDL25826.1|/1.53366e-175/WD repeat domain 61, isoform CRA_a, partial [Mus musculus]" 27756 890 11.63333333 11.38333333 -0.031341458 Down 0.124873068 Lsm2 "LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated" K12621|1|6e-63|243|rno:684148|U6 snRNA-associated Sm-like protein LSm2 - - - - 382423 3607 10.56666667 10.31666667 -0.034543431 Down 0.124873068 Atxn7l3b ataxin 7-like 3B K11363|1|2e-22|111|cge:100754412|SAGA-associated factor 11 - - - gi|113930747|ref|NP_001028646.2|/7.75926e-50/putative ataxin-7-like protein 3B [Mus musculus] 227619 3748 11.89 11.64333333 -0.030244573 Down 0.124873068 Man1b1 "mannosidase, alpha, class 1B, member 1" "K01230|1|0.0|1249|mmu:227619|mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding;GO:0015924//mannosyl-oligosaccharide mannosidase activity GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process "gi|71534295|ref|NP_001025154.1|/0/endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase [Mus musculus]" 17897 898 6459.433333 6541.243333 0.018157276 Up 0.124854263 Myl3 "myosin, light polypeptide 3" K12749|1|2e-86|320|mmu:17897|myosin light chain 3 GO:0015629//actin cytoskeleton;GO:0030017//sarcomere GO:0017111//nucleoside-triphosphatase activity;GO:0046872//metal ion binding;GO:0003779//actin binding GO:0006941//striated muscle contraction;GO:0008016//regulation of heart contraction;GO:0003208//cardiac ventricle morphogenesis;GO:0014706//striated muscle tissue development;GO:0006937//regulation of muscle contraction "gi|148677054|gb|EDL09001.1|/1.97921e-85/myosin, light polypeptide 3, isoform CRA_a, partial [Mus musculus]" 11947 1879 3566.233333 3625.38 0.023731122 Up 0.124844861 Atp5b "ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit" K02133|1|0.0|919|mmu:11947|F-type H+-transporting ATPase subunit beta [EC:3.6.3.14] "GO:0005759//mitochondrial matrix;GO:0000275//mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)" GO:0042287//MHC protein binding;GO:0032550;GO:0019829//cation-transporting ATPase activity;GO:0038024//cargo receptor activity;GO:0046872//metal ion binding "GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0006929//substrate-dependent cell migration;GO:0022900//electron transport chain;GO:0006754//ATP biosynthetic process;GO:0006897//endocytosis;GO:0009154//purine ribonucleotide catabolic process;GO:0030641//regulation of cellular pH;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0006839//mitochondrial transport" "gi|31980648|ref|NP_058054.2|/0/ATP synthase subunit beta, mitochondrial precursor [Mus musculus]" 11938 4365.9 3645.486667 3587.5 -0.023132593 Down 0.124844861 Atp2a2 "ATPase, Ca++ transporting, cardiac muscle, slow twitch 2" "K05853|1|0.0|2035|mmu:11938|Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]" GO:0032991//macromolecular complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0032991//macromolecular complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0032991//macromolecular complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane GO:0032550;GO:0046872//metal ion binding;GO:0005388//calcium-transporting ATPase activity;GO:0001664//G-protein coupled receptor binding;GO:0032550;GO:0046872//metal ion binding;GO:0005388//calcium-transporting ATPase activity;GO:0001664//G-protein coupled receptor binding;GO:0032550;GO:0046872//metal ion binding;GO:0005388//calcium-transporting ATPase activity;GO:0001664//G-protein coupled receptor binding GO:0002027//regulation of heart rate;GO:0009888//tissue development;GO:0007599//hemostasis;GO:0006816//calcium ion transport;GO:0090075//relaxation of muscle;GO:0006936//muscle contraction;GO:0022610;GO:0007165//signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0042391//regulation of membrane potential;GO:0009725//response to hormone;GO:0006875//cellular metal ion homeostasis;GO:0002027//regulation of heart rate;GO:0009888//tissue development;GO:0007599//hemostasis;GO:0006816//calcium ion transport;GO:0090075//relaxation of muscle;GO:0006936//muscle contraction;GO:0022610;GO:0007165//signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0042391//regulation of membrane potential;GO:0009725//response to hormone;GO:0006875//cellular metal ion homeostasis;GO:0002027//regulation of heart rate;GO:0009888//tissue development;GO:0007599//hemostasis;GO:0006816//calcium ion transport;GO:0090075//relaxation of muscle;GO:0006936//muscle contraction;GO:0022610;GO:0007165//signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0042391//regulation of membrane potential;GO:0009725//response to hormone;GO:0006875//cellular metal ion homeostasis gi|158635979|ref|NP_001103610.1|/0/sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform b [Mus musculus] 71679 574 1422.543333 1442.58 0.020178727 Up 0.124779044 Atp5h "ATP synthase, H+ transporting, mitochondrial F0 complex, subunit D" K02138|1|3e-90|332|mmu:71679|F-type H+-transporting ATPase subunit d "GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain" GO:0017111//nucleoside-triphosphatase activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0009154//purine ribonucleotide catabolic process "gi|21313679|ref|NP_082138.1|/1.84972e-89/ATP synthase subunit d, mitochondrial [Mus musculus]" 231125 3980 0.246666667 0.203333333 -0.278716028 Down 0.124666215 Zfyve28 "zinc finger, FYVE domain containing 28" K17603|1|5e-93|345|bmor:101744058|zinc finger FYVE domain-containing protein 1;K18082|4|2e-16|91.3|isc:IscW_ISCW014883|myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95] - - - - 225743 7321 0.186666667 0.226666667 0.280107919 Up 0.124666215 Rnf165 ring finger protein 165 K17821|1|0.0|677|mmu:225743|RING finger protein 165 - - - - 66123 768 0.2 0.243333333 0.282933963 Up 0.124666215 1110006O24Rik RIKEN cDNA 1110006O24 gene - - - - "gi|148687900|gb|EDL19847.1|/8.46435e-41/RIKEN cDNA 1110006O24, partial [Mus musculus]" 245622 8308 0.173333333 0.21 0.276840205 Up 0.124666215 Fam199x "family with sequence similarity 199, X-linked" - - - - "gi|148691944|gb|EDL23891.1|/0/cDNA sequence BC031748, partial [Mus musculus]" 27103 5113.82 1.883333333 1.973333333 0.067346308 Up 0.124666215 Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 K16196|1|0.0|3022|mmu:27103|eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1] - - - gi|295317391|ref|NP_001171277.1|/0/eIF-2-alpha kinase GCN2 isoform 2 [Mus musculus] 215193 5548 1.776666667 1.87 0.073865238 Up 0.124666215 Diexf digestive organ expansion factor homolog (zebrafish) K14774|1|0.0|1367|mmu:215193|U3 small nucleolar RNA-associated protein 25 GO:0031981//nuclear lumen - GO:0032502//developmental process gi|56790942|ref|NP_663390.2|/0/digestive organ expansion factor homolog [Mus musculus] 317757 1943 1.656666667 1.743333333 0.073565095 Up 0.124666215 Gimap5 "GTPase, IMAP family member 5" - GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane GO:0032550 "GO:0006915//apoptotic process;GO:0048871//multicellular organismal homeostasis;GO:0002260//lymphocyte homeostasis;GO:0006809//nitric oxide biosynthetic process;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0002361//CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0042391//regulation of membrane potential;GO:0010522//regulation of calcium ion transport into cytosol;GO:0009895;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0002370;GO:0000002//mitochondrial genome maintenance;GO:0042492//gamma-delta T cell differentiation;GO:0001773//myeloid dendritic cell activation;GO:0006839//mitochondrial transport;GO:0001818//negative regulation of cytokine production" gi|568942086|ref|XP_006506291.1|/6.80889e-169/PREDICTED: GTPase IMAP family member 5 isoform X2 [Mus musculus] 320271 10705 0.2 0.243333333 0.282933963 Up 0.124666215 Scai suppressor of cancer cell invasion K15498|1|4e-81|307|tru:101070162|serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0003712//transcription cofactor activity "GO:0016477//cell migration;GO:0006351//transcription, DNA-templated;GO:0007266//Rho protein signal transduction" gi|86198339|ref|NP_848893.2|/0/protein SCAI [Mus musculus] 12291 8159 1.883333333 1.79 -0.073328779 Down 0.124666215 Cacna1g "calcium channel, voltage-dependent, T type, alpha 1G subunit" K04854|1|0.0|3708|mmu:12291|voltage-dependent calcium channel T type alpha-1G - - - gi|163914402|ref|NP_033913.2|/0/voltage-dependent T-type calcium channel subunit alpha-1G isoform a [Mus musculus] 77920 743 0.223333333 0.183333333 -0.284729477 Down 0.124666215 A330102I10Rik RIKEN cDNA A330102I10 gene - - - - - 232313 1826 0.243333333 0.2 -0.282933963 Down 0.124666215 Gxylt2 glucoside xylosyltransferase 2 "K13676|1|0.0|786|mmu:232313|UDP-xylose:glucoside alpha-1,3-xylosyltransferase [EC:2.4.2.-]" GO:0031224//intrinsic component of membrane GO:0008194//UDP-glycosyltransferase activity GO:0006493//protein O-linked glycosylation gi|38348470|ref|NP_941014.1|/0/glucoside xylosyltransferase 2 precursor [Mus musculus] 216835 4447 1.836666667 1.746666667 -0.072485507 Down 0.124666215 Usp43 ubiquitin specific peptidase 43 K11856|1|0.0|2027|mmu:216835|ubiquitin carboxyl-terminal hydrolase 43 [EC:3.4.19.12] - - - gi|123314452|ref|NP_776115.2|/0/ubiquitin carboxyl-terminal hydrolase 43 isoform 1 [Mus musculus] 71951 2513 0.203333333 0.246666667 0.278716028 Up 0.124666215 Gpc2 glypican 2 (cerebroglycan) K08108|1|0.0|939|mmu:71951|glypican 2 GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0031012//extracellular matrix;GO:0044431//Golgi apparatus part;GO:0044421 GO:0043168//anion binding GO:0044238//primary metabolic process;GO:0006026;GO:0006790//sulfur compound metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0030154//cell differentiation;GO:0006023 "gi|148687250|gb|EDL19197.1|/0/glypican 2 (cerebroglycan), isoform CRA_d, partial [Mus musculus]" 407785 527.42 652.99 642.29 -0.023836063 Down 0.124553387 Ndufs6 NADH dehydrogenase (ubiquinone) Fe-S protein 6 K03939|1|2e-63|243|mmu:407785|NADH dehydrogenase (ubiquinone) Fe-S protein 6 GO:0005746//mitochondrial respiratory chain;GO:0005746//mitochondrial respiratory chain - GO:0048731//system development;GO:0022900//electron transport chain;GO:0032787//monocarboxylic acid metabolic process;GO:0040007//growth;GO:0003012//muscle system process;GO:0007005//mitochondrion organization;GO:0051234//establishment of localization;GO:0048731//system development;GO:0022900//electron transport chain;GO:0032787//monocarboxylic acid metabolic process;GO:0040007//growth;GO:0003012//muscle system process;GO:0007005//mitochondrion organization;GO:0051234//establishment of localization "gi|56711244|ref|NP_035018.1|/1.46173e-62/NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial precursor [Mus musculus]" 27425 529 766.4566667 776.22 0.018261378 Up 0.12452518 Atp5l "ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G" K02140|1|5e-53|208|mmu:27425|F-type H+-transporting ATPase subunit g GO:0005743//mitochondrial inner membrane GO:0017111//nucleoside-triphosphatase activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006754//ATP biosynthetic process;GO:0009154//purine ribonucleotide catabolic process;GO:0006811//ion transport gi|12841973|dbj|BAB25423.1|/1.32948e-61/unnamed protein product [Mus musculus] 319670 10136 1.45 1.373333333 -0.078371064 Down 0.124496972 Eml5 echinoderm microtubule associated protein like 5 K18597|1|0.0|3916|mmu:319670|echinoderm microtubule-associated protein-like 5 - - - gi|124487111|ref|NP_001074660.1|/0/echinoderm microtubule-associated protein-like 5 [Mus musculus] 70620 5881.99 1.603333333 1.52 -0.07700307 Down 0.124496972 Ube2v2 ubiquitin-conjugating enzyme E2 variant 2 K10704|1|6e-47|193|hgl:101706436|ubiquitin-conjugating enzyme E2 variant GO:0043231//intracellular membrane-bounded organelle;GO:0031371//ubiquitin conjugating enzyme complex "GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0005488//binding" "GO:0043066//negative regulation of apoptotic process;GO:0010975//regulation of neuron projection development;GO:0016567//protein ubiquitination;GO:0031331;GO:0000738//DNA catabolic process, exonucleolytic;GO:0006301//postreplication repair;GO:0007416//synapse assembly" gi|507625712|ref|XP_004697820.1|/1.33272e-54/PREDICTED: ubiquitin-conjugating enzyme E2 variant 2 [Echinops telfairi] 235050 3238 1.43 1.353333333 -0.07949792 Down 0.124496972 Zfp810 zinc finger protein 810 K09228|1|0.0|1002|mmu:235050|KRAB domain-containing zinc finger protein - GO:0043169//cation binding GO:0045165//cell fate commitment;GO:0022612//gland morphogenesis;GO:0030324//lung development "gi|148693322|gb|EDL25269.1|/0/cDNA sequence BC005471, isoform CRA_a, partial [Mus musculus]" 17218 3417 1.48 1.56 0.075948853 Up 0.124496972 Mcm5 minichromosome maintenance complex component 5 K02209|1|0.0|1452|mmu:17218|DNA replication licensing factor MCM5 [EC:3.6.4.12] GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0032550;GO:0003676//nucleic acid binding;GO:0004386//helicase activity;GO:0032550;GO:0003676//nucleic acid binding;GO:0004386//helicase activity GO:0044772//mitotic cell cycle phase transition;GO:0006261//DNA-dependent DNA replication;GO:0051320;GO:0032392//DNA geometric change;GO:0044772//mitotic cell cycle phase transition;GO:0006261//DNA-dependent DNA replication;GO:0051320;GO:0032392//DNA geometric change gi|112293273|ref|NP_032592.2|/0/DNA replication licensing factor MCM5 [Mus musculus] 170761 2181 1.456666667 1.376666667 -0.081491498 Down 0.124496972 Pdzd3 PDZ domain containing 3 K13358|1|2e-32|143|hgl:101719159|Na(+)/H(+) exchange regulatory cofactor NHE-RF2 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding GO:0031280 gi|153791851|ref|NP_573489.2|/0/Na(+)/H(+) exchange regulatory cofactor NHE-RF4 [Mus musculus] 27221 3308 1.42 1.343333333 -0.080073592 Down 0.124496972 Chaf1a "chromatin assembly factor 1, subunit A (p150)" K10750|1|0.0|849|mmu:27221|chromatin assembly factor 1 subunit A GO:0070603//SWI/SNF superfamily-type complex GO:0019904//protein domain specific binding "GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006333//chromatin assembly or disassembly;GO:0006351//transcription, DNA-templated" gi|74145400|dbj|BAE36149.1|/0/unnamed protein product [Mus musculus] 69605 8692 1.46 1.54 0.076961982 Up 0.124496972 Lnp ER junction formation factor 1 - - - - - 213236 1490 1.366666667 1.446666667 0.082071133 Up 0.124496972 Dnd1 DND microRNA-mediated repression inhibitor 1 K13161|1|2e-22|109|mze:101483948|heterogeneous nuclear ribonucleoprotein R;K13160|5|5e-22|108|xma:102222439|heterogeneous nuclear ribonucleoprotein Q - - - - 319277 5863 1.4 1.323333333 -0.081250321 Down 0.124496972 A230046K03Rik RIKEN cDNA A230046K03 gene K18465|1|0.0|2163|mmu:319277|WASH complex subunit 7 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0044765//single-organism transport gi|126090572|ref|NP_001028547.2|/0/WASH complex subunit 7 [Mus musculus] 12858 707 776.6 767.73 -0.016572683 Down 0.124468765 Cox5a cytochrome c oxidase subunit Va K02264|1|6e-63|242|rno:252934|cytochrome c oxidase subunit 5a GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0015002//heme-copper terminal oxidase activity GO:0044710 "gi|686745375|ref|XP_002824834.2|/3.38373e-62/PREDICTED: cytochrome c oxidase subunit 5A, mitochondrial-like [Pongo abelii]" 66576 562 827.4933333 818.6466667 -0.01550678 Down 0.124468765 Uqcrh ubiquinol-cytochrome c reductase hinge protein K00416|1|3e-42|172|mmu:66576|ubiquinol-cytochrome c reductase subunit 6 GO:0005746//mitochondrial respiratory chain GO:0015078//hydrogen ion transmembrane transporter activity;GO:0005515//protein binding GO:0051259//protein oligomerization;GO:0022904//respiratory electron transport chain;GO:0051234//establishment of localization "gi|21539599|ref|NP_079917.1|/2.28373e-41/cytochrome b-c1 complex subunit 6, mitochondrial [Mus musculus]" 109135 5133 3.456666667 3.58 0.050578099 Up 0.124449961 Plekha5 "pleckstrin homology domain containing, family A member 5" K17536|1|4e-13|80.9|mze:101484241|connector enhancer of kinase suppressor of Ras 2 - - - gi|110835706|ref|NP_659169.3|/0/pleckstrin homology domain-containing family A member 5 [Mus musculus] 100504184 399 0.403333333 0.356666667 -0.177396251 Down 0.124449961 Gm16336 predicted gene 16336 "K12337|1|2e-06|53.1|cge:100757809|inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate" - - - - 170460 2500 3.656666667 3.536666667 -0.048138869 Down 0.124449961 Stard5 StAR-related lipid transfer (START) domain containing 5 "K16931|1|3e-12|76.6|bacu:103013722|steroidogenic acute regulatory protein, mitochondrial" - GO:0015248//sterol transporter activity;GO:0005488//binding GO:0051234//establishment of localization;GO:0010876//lipid localization gi|11992399|gb|AAG41056.1|/1.6003e-128/StAR-related protein 1-4E [Mus musculus] 72745 2689.87 3.82 3.7 -0.046047368 Down 0.124449961 Tmem161b transmembrane protein 161B - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|568983685|ref|XP_006517465.1|/0/PREDICTED: transmembrane protein 161B isoform X1 [Mus musculus] 53334 4265 6.363333333 6.21 -0.035189428 Down 0.124449961 Gosr1 golgi SNAP receptor complex member 1 K08495|1|1e-137|494|mmu:53334|golgi SNAP receptor complex member 1 GO:0031985//Golgi cisterna;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane GO:0005515//protein binding GO:0048193//Golgi vesicle transport;GO:0016482//cytosolic transport;GO:0045184//establishment of protein localization gi|31542904|ref|NP_058090.2|/1.00744e-136/Golgi SNAP receptor complex member 1 [Mus musculus] 14011 5643.91 3.366666667 3.483333333 0.049147649 Up 0.124449961 Etv6 ets variant 6 K03211|1|0.0|1008|mmu:14011|ETS translocation variant 6/7 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding "GO:0048869//cellular developmental process;GO:0006351//transcription, DNA-templated;GO:0048869//cellular developmental process;GO:0006351//transcription, DNA-templated" gi|84370337|ref|NP_031987.3|/0/transcription factor ETV6 isoform 1 [Mus musculus] 17345 10098 0.416666667 0.366666667 -0.184424571 Down 0.124449961 Mki67 antigen identified by monoclonal antibody Ki 67 K17582|1|0.0|5999|mmu:17345|antigen KI-67 GO:0044446;GO:0005634//nucleus GO:0005515//protein binding GO:0044699 gi|169234624|ref|NP_001074586.2|/0/antigen KI-67 [Mus musculus] 12009 3589 5.353333333 5.206666667 -0.040077439 Down 0.124449961 Cep131 centrosomal protein 131 K16540|1|0.0|1506|mmu:12009|5-azacytidine-induced protein 1 - - GO:0048232//male gamete generation;GO:0032502//developmental process gi|294345409|ref|NP_033864.3|/0/centrosomal protein of 131 kDa [Mus musculus] 106564 1440 5.706666667 5.856666667 0.03743149 Up 0.124449961 Ppcs phosphopantothenoylcysteine synthetase K01922|1|2e-140|501|mmu:106564|phosphopantothenate-cysteine ligase [EC:6.3.2.5] - GO:0016881//acid-amino acid ligase activity - gi|76096364|ref|NP_080770.2|/1.30262e-139/phosphopantothenate--cysteine ligase [Mus musculus] 170767 2185 6.206666667 6.36 0.035208098 Up 0.124449961 Rfxap regulatory factor X-associated protein K08063|1|1e-67|260|mmu:170767|regulatory factor X-associated protein GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated" gi|18875392|ref|NP_573494.1|/1.13142e-66/regulatory factor X-associated protein [Mus musculus] 57914 1410.7 5.03 5.18 0.042393698 Up 0.124449961 Crlf2 cytokine receptor-like factor 2 K05078|1|2e-149|531|mmu:57914|thymic stromal-derived lymphopoietin receptor GO:0016020//membrane - - gi|893553963|ref|NP_001297623.1|/8.01292e-161/cytokine receptor-like factor 2 isoform 3 [Mus musculus] 72500 1572 3.233333333 3.113333333 -0.054562197 Down 0.124449961 Ier5l immediate early response 5-like - - - - gi|26329649|dbj|BAC28563.1|/7.82331e-132/unnamed protein product [Mus musculus] 73212 1481 3.34 3.216666667 -0.054281661 Down 0.124449961 3110082I17Rik RIKEN cDNA 3110082I17 gene - - - - gi|12852007|dbj|BAB29235.1|/2.19349e-87/unnamed protein product [Mus musculus] 108123 3496 6.173333333 6.02 -0.036286206 Down 0.124449961 Napg N-ethylmaleimide sensitive fusion protein attachment protein gamma K10600|1|1e-41|175|hmg:100197482|U-box domain-containing protein 5;K15296|2|3e-09|67.4|hro:HELRODRAFT_157419|alpha-soluble NSF attachment protein GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0065003;GO:0048193//Golgi vesicle transport;GO:0031647//regulation of protein stability;GO:0015031//protein transport gi|110625902|ref|NP_082293.1|/1.01012e-163/gamma-soluble NSF attachment protein [Mus musculus] 68194 454 561.49 568.5466667 0.018018442 Up 0.124402949 Ndufb4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4 K03960|1|2e-70|265|mmu:68194|NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4 GO:0005746//mitochondrial respiratory chain - GO:0006950//response to stress gi|21314826|ref|NP_080886.1|/1.62033e-69/NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 [Mus musculus] 109361 3607 0.193333333 0.233333333 0.271302022 Up 0.124402949 D730005E14Rik RIKEN cDNA D730005E14 gene - - - - gi|74180681|dbj|BAE25568.1|/4.25765e-48/unnamed protein product [Mus musculus] 77739 7839 0.246666667 0.206666667 -0.255257055 Down 0.124402949 Adamtsl1 ADAMTS-like 1 K08627|1|4e-88|330|xtr:100485801|a disintegrin and metalloproteinase with thrombospondin motifs 13 [EC:3.4.24.87] - - - gi|161353491|ref|NP_084243.3|/0/ADAMTS-like protein 1 precursor [Mus musculus] 207921 2886 0.223333333 0.186666667 -0.258734268 Down 0.124402949 Fam228b "family with sequence similarity 228, member B" - - - - gi|139948413|ref|NP_780640.2|/6.28741e-132/protein FAM228B [Mus musculus] 216456 2380 0.18 0.216666667 0.267480311 Up 0.124402949 Gls2 "glutaminase 2 (liver, mitochondrial)" K01425|1|0.0|945|mmu:216456|glutaminase [EC:3.5.1.2] GO:0044429;GO:0044429 "GO:0005488//binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0005488//binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0006915//apoptotic process;GO:0009064//glutamine family amino acid metabolic process;GO:0001505//regulation of neurotransmitter levels;GO:0006835//dicarboxylic acid transport;GO:0006915//apoptotic process;GO:0009064//glutamine family amino acid metabolic process;GO:0001505//regulation of neurotransmitter levels;GO:0006835//dicarboxylic acid transport gi|60359874|dbj|BAD90156.1|/0/mKIAA4146 protein [Mus musculus] 243910 2010 0.22 0.183333333 -0.263034406 Down 0.124402949 Nfkbid "nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta" K14214|1|0.0|742|cge:100772746|NF-kappa-B inhibitor delta - - - gi|880945070|ref|XP_005081875.2|/0/PREDICTED: NF-kappa-B inhibitor delta [Mesocricetus auratus] 269209 5329 0.18 0.216666667 0.267480311 Up 0.124402949 Stk36 serine/threonine kinase 36 K06228|1|0.0|2207|mmu:269209|fused [EC:2.7.11.1] - - - "gi|148667927|gb|EDL00344.1|/0/serine/threonine kinase 36 (fused homolog, Drosophila), isoform CRA_c, partial [Mus musculus]" 70178 2252 12.21333333 11.97 -0.02903385 Down 0.124337132 Abhd17c abhydrolase domain containing 17C K06889|1|9e-16|88.2|pxy:105384212|uncharacterized protein - GO:0003824//catalytic activity - gi|532029592|ref|XP_005357748.1|/7.1836e-157/PREDICTED: alpha/beta hydrolase domain-containing protein 17C [Microtus ochrogaster] 56455 2037 11.71666667 11.95666667 0.029253056 Up 0.124337132 Dynll1 dynein light chain LC8-type 1 K10418|1|6e-51|204|phd:102338635|dynein light chain LC8-type "GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0000775//chromosome, centromeric region;GO:0030286//dynein complex;GO:0044444//cytoplasmic part" GO:0017111//nucleoside-triphosphatase activity;GO:0042802//identical protein binding;GO:0030234//enzyme regulator activity "GO:0051234//establishment of localization;GO:0007010//cytoskeleton organization;GO:0006351//transcription, DNA-templated;GO:0044772//mitotic cell cycle phase transition;GO:0012501//programmed cell death;GO:0006928//movement of cell or subcellular component;GO:0016310//phosphorylation;GO:0006809//nitric oxide biosynthetic process;GO:0044092//negative regulation of molecular function;GO:0001505//regulation of neurotransmitter levels;GO:0007276//gamete generation;GO:0019222//regulation of metabolic process;GO:0002478;GO:0032502//developmental process" "gi|537236584|gb|ERE85696.1|/6.06715e-53/dynein light chain 1, cytoplasmic-like protein [Cricetulus griseus]" 20720 2071 13.15 12.91 -0.026573799 Down 0.124337132 Serpine2 "serine (or cysteine) peptidase inhibitor, clade E, member 2" K16643|1|0.0|786|mmu:20720|glia-derived nexin - - - gi|6678099|ref|NP_033281.1|/0/glia-derived nexin precursor [Mus musculus] 243846 2127.64 11.73333333 11.97 0.028810224 Up 0.124337132 Ccdc9 coiled-coil domain containing 9 - - - - gi|210147499|ref|NP_001129943.1|/0/coiled-coil domain-containing protein 9 isoform 1 [Mus musculus] 67130 560 388.6166667 382.6266667 -0.022410351 Down 0.124318327 Ndufa6 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (B14)" K03950|1|5e-62|238|mmu:67130|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6 GO:0005746//mitochondrial respiratory chain - GO:0051234//establishment of localization;GO:0006950//response to stress;GO:0006091//generation of precursor metabolites and energy gi|13385492|ref|NP_080263.1|/3.38893e-61/NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 [Mus musculus] 72900 1540 265.82 270.4366667 0.024841115 Up 0.124139682 Ndufv2 NADH dehydrogenase (ubiquinone) flavoprotein 2 K03943|1|2e-134|482|mmu:72900|NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3] - - - - 74166 2109 341.3733333 336.8766667 -0.01912986 Down 0.12409267 Tmem38a transmembrane protein 38A - GO:0005789//endoplasmic reticulum membrane;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane GO:0005227//calcium activated cation channel activity GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|21362331|ref|NP_653117.1|/1.33462e-165/trimeric intracellular cation channel type A [Mus musculus] 70257 365 424.31 428.7566667 0.015040424 Up 0.124083268 2010107E04Rik RIKEN cDNA 2010107E04 gene K18193|1|5e-28|124|mmu:70257|6.8 kDa mitochondrial proteolipid GO:0005743//mitochondrial inner membrane;GO:0031224//intrinsic component of membrane - - gi|21312554|ref|NP_081636.1|/4.48092e-27/6.8 kDa mitochondrial proteolipid [Mus musculus] 67914 1693 341.1966667 345.53 0.018207423 Up 0.12405506 Coq9 coenzyme Q9 K18587|1|7e-133|476|mmu:67914|ubiquinone biosynthesis protein COQ9 - - - - 77519 6294.01 2.323333333 2.223333333 -0.063471895 Down 0.123885817 Zfp266 zinc finger protein 266 K09228|1|0.0|1285|mmu:77519|KRAB domain-containing zinc finger protein - GO:0043169//cation binding;GO:0043169//cation binding - gi|203097452|ref|NP_001075954.1|/0/zinc finger protein 426-like [Mus musculus] 100503041 3927 2.436666667 2.336666667 -0.060456962 Down 0.123885817 Pdzd7 PDZ domain containing 7 K16175|1|2e-15|88.2|tca:659629|protein scribble;K06095|3|2e-15|88.2|sko:100371024|multiple PDZ domain protein;K12076|5|1e-14|85.5|tad:TRIADDRAFT_63520|disks large protein 1 GO:0043231//intracellular membrane-bounded organelle - - gi|305682586|ref|NP_001182194.1|/0/PDZ domain-containing protein 7 [Mus musculus] 68453 826 206.4 209.84 0.023846742 Up 0.123885817 Gpihbp1 GPI-anchored HDL-binding protein 1 K20001|1|4e-118|426|mmu:68453|glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 GO:0034358//plasma lipoprotein particle;GO:0009986//cell surface;GO:0046658//anchored component of plasma membrane GO:0071813//lipoprotein particle binding;GO:0008565//protein transporter activity;GO:0019899//enzyme binding GO:0016192//vesicle-mediated transport;GO:0055092//sterol homeostasis;GO:0010986;GO:0010243//response to organonitrogen compound;GO:0051004;GO:0055090//acylglycerol homeostasis;GO:0015918//sterol transport;GO:0031647//regulation of protein stability;GO:0034613//cellular protein localization;GO:0051130//positive regulation of cellular component organization;GO:0015031//protein transport gi|58037121|ref|NP_081006.1|/2.86557e-117/glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 precursor [Mus musculus] 17126 8770.89 2.403333333 2.306666667 -0.059227222 Down 0.123885817 Smad2 SMAD family member 2 K04500|1|0.0|872|mmu:17126|mothers against decapentaplegic homolog 2/3 - - - gi|524953051|ref|XP_005076516.1|/0/PREDICTED: mothers against decapentaplegic homolog 2 isoform X2 [Mesocricetus auratus] 66756 4539 2.426666667 2.526666667 0.058259398 Up 0.123885817 Cfap97 cilia and flagella associated protein 97 - - - - gi|37360380|dbj|BAC98168.1|/0/mKIAA1430 protein [Mus musculus] 20238 10474 2.343333333 2.446666667 0.062255374 Up 0.123885817 Atxn1 ataxin 1 "K14718|1|8e-29|134|bfo:BRAFLDRAFT_68432|solute carrier family 39 (zinc transporter), member 12" - - - - 327872 3376 0.453333333 0.403333333 -0.168599604 Down 0.123725977 Gm12018 predicted gene 12018 K04534|1|2e-16|69.7|lcm:102363494|guanine nucleotide-binding protein G(o) subunit alpha;K11290|3|5e-12|68.2|rno:317165|template-activating factor I;K11650|5|6e-09|66.2|xtr:100495941|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D - - - - 192140 3216 0.44 0.39 -0.1740294 Down 0.123725977 Tmc2 transmembrane channel-like gene family 2 K10877|1|3e-30|137|tsp:Tsp_10860|DNA repair and recombination protein RAD54B [EC:3.6.4.-] - - - - 15478 3933 0.38 0.426666667 0.167109986 Up 0.123725977 Hs3st3a1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 K07809|1|1e-178|630|mmu:15478|[heparan sulfate]-glucosamine 3-sulfotransferase 3 [EC:2.8.2.30] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0034483//heparan sulfate sulfotransferase activity - gi|30725857|ref|NP_849201.1|/8.22425e-178/heparan sulfate glucosamine 3-O-sulfotransferase 3A1 [Mus musculus] 69697 4303.18 0.486666667 0.433333333 -0.167456746 Down 0.123725977 Camsap3 "calmodulin regulated spectrin-associated protein family, member 3" K17493|1|0.0|1887|mmu:69697|calmodulin-regulated spectrin-associated protein GO:0015630//microtubule cytoskeleton;GO:0005913//cell-cell adherens junction;GO:0015630//microtubule cytoskeleton;GO:0005913//cell-cell adherens junction GO:0008017//microtubule binding;GO:0008017//microtubule binding GO:0016337//single organismal cell-cell adhesion;GO:0045217//cell-cell junction maintenance;GO:0000226//microtubule cytoskeleton organization;GO:0010921//regulation of phosphatase activity;GO:0016337//single organismal cell-cell adhesion;GO:0045217//cell-cell junction maintenance;GO:0000226//microtubule cytoskeleton organization;GO:0010921//regulation of phosphatase activity "gi|148689975|gb|EDL21922.1|/0/RIKEN cDNA 2310057J16, isoform CRA_b, partial [Mus musculus]" 67230 7933 0.406666667 0.456666667 0.167294745 Up 0.123725977 Zfp329 zinc finger protein 329 K09228|1|3e-145|520|cfr:106728490|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|12850536|dbj|BAB28761.1|/0/unnamed protein product [Mus musculus] 30853 1530.43 168.3266667 171.2033333 0.024447042 Up 0.123669563 Mlf2 myeloid leukemia factor 2 K15622|1|9e-41|170|xla:496153|myeloid leukemia factor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0006950//response to stress;GO:0006950//response to stress gi|625280369|ref|XP_007631839.1|/3.26328e-128/PREDICTED: myeloid leukemia factor 2 isoform X2 [Cricetulus griseus] 219158 3705 10.32 10.09333333 -0.032040266 Down 0.123669563 Ccar2 cell cycle activator and apoptosis regulator 2 - - - - "gi|148703976|gb|EDL35923.1|/0/mCG3854, isoform CRA_a, partial [Mus musculus]" 54645 3015.61 11.92 12.14666667 0.027176223 Up 0.123669563 Gripap1 GRIP1 associated protein 1 K02433|1|1e-34|151|crg:105322865|aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7];K10448|2|9e-19|98.6|hro:HELRODRAFT_194422|kelch-like protein 10;K20478|3|8e-18|95.5|spu:576978|golgin subfamily B member 1 - - - gi|594190856|ref|NP_001277384.1|/0/GRIP1-associated protein 1 isoform 1 [Mus musculus] 17346 2605.71 9.723333333 9.956666667 0.034211851 Up 0.123669563 Mknk1 MAP kinase-interacting serine/threonine kinase 1 K04372|1|0.0|721|mmu:17346|MAP kinase interacting serine/threonine kinase [EC:2.7.11.1] - GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity GO:0006412//translation;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0006412//translation;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0006412//translation;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction gi|880892706|ref|XP_012970390.1|/0/PREDICTED: MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1 [Mesocricetus auratus] 14694 1254 202.2233333 199.6666667 -0.018355968 Down 0.123575539 Rack1 receptor for activated C kinase 1 K14753|1|0.0|677|nle:100586801|guanine nucleotide-binding protein subunit beta-2-like 1 protein GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0043025//neuronal cell body;GO:0044391//ribosomal subunit GO:0016505//peptidase activator activity involved in apoptotic process;GO:0005102//receptor binding;GO:0016248//channel inhibitor activity;GO:0019902//phosphatase binding;GO:0019904//protein domain specific binding;GO:0019901//protein kinase binding;GO:0004860//protein kinase inhibitor activity GO:0007369//gastrulation;GO:0016055//Wnt signaling pathway;GO:0008104//protein localization;GO:0016049//cell growth;GO:0097193//intrinsic apoptotic signaling pathway;GO:0016477//cell migration;GO:0006469//negative regulation of protein kinase activity;GO:0032461//positive regulation of protein oligomerization;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0007049//cell cycle;GO:0007186//G-protein coupled receptor signaling pathway;GO:0043087//regulation of GTPase activity;GO:0031331;GO:0006412//translation;GO:0006909//phagocytosis gi|820973213|ref|XP_003279626.2|/0/PREDICTED: guanine nucleotide-binding protein subunit beta-2-like 1 isoform X1 [Nomascus leucogenys] 100073351 2867 0.77 0.706666667 -0.123828587 Down 0.123528527 Yy2 Yy2 transcription factor K09201|1|0.0|787|mmu:100073351|transcription factor YY - - - gi|148922953|ref|NP_001092193.1|/0/transcription factor YY2 [Mus musculus] 13805 3444.29 165.95 168.4933333 0.021942881 Up 0.123528527 Eng endoglin K06526|1|0.0|1229|mmu:13805|endoglin GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0072562//blood microparticle;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0072562//blood microparticle;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0072562//blood microparticle GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0048029//monosaccharide binding;GO:0005160//transforming growth factor beta receptor binding;GO:0097367//carbohydrate derivative binding;GO:0042802//identical protein binding;GO:0019838//growth factor binding;GO:0005057//receptor signaling protein activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0048029//monosaccharide binding;GO:0005160//transforming growth factor beta receptor binding;GO:0097367//carbohydrate derivative binding;GO:0042802//identical protein binding;GO:0019838//growth factor binding;GO:0005057//receptor signaling protein activity;GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0048029//monosaccharide binding;GO:0005160//transforming growth factor beta receptor binding;GO:0097367//carbohydrate derivative binding;GO:0042802//identical protein binding;GO:0019838//growth factor binding;GO:0005057//receptor signaling protein activity GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0003272//endocardial cushion formation;GO:0032769//negative regulation of monooxygenase activity;GO:0001935//endothelial cell proliferation;GO:0022411;GO:0001933//negative regulation of protein phosphorylation;GO:0007569//cell aging;GO:0016477//cell migration;GO:0001666//response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0060537//muscle tissue development;GO:0006935//chemotaxis;GO:0022610;GO:0003073//regulation of systemic arterial blood pressure;GO:0030198//extracellular matrix organization;GO:0001570//vasculogenesis;GO:0048545//response to steroid hormone;GO:0003143//embryonic heart tube morphogenesis;GO:0001525//angiogenesis;GO:0009611//response to wounding;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0003272//endocardial cushion formation;GO:0032769//negative regulation of monooxygenase activity;GO:0001935//endothelial cell proliferation;GO:0022411;GO:0001933//negative regulation of protein phosphorylation;GO:0007569//cell aging;GO:0016477//cell migration;GO:0001666//response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0060537//muscle tissue development;GO:0006935//chemotaxis;GO:0022610;GO:0003073//regulation of systemic arterial blood pressure;GO:0030198//extracellular matrix organization;GO:0001570//vasculogenesis;GO:0048545//response to steroid hormone;GO:0003143//embryonic heart tube morphogenesis;GO:0001525//angiogenesis;GO:0009611//response to wounding;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0003272//endocardial cushion formation;GO:0032769//negative regulation of monooxygenase activity;GO:0001935//endothelial cell proliferation;GO:0022411;GO:0001933//negative regulation of protein phosphorylation;GO:0007569//cell aging;GO:0016477//cell migration;GO:0001666//response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0060537//muscle tissue development;GO:0006935//chemotaxis;GO:0022610;GO:0003073//regulation of systemic arterial blood pressure;GO:0030198//extracellular matrix organization;GO:0001570//vasculogenesis;GO:0048545//response to steroid hormone;GO:0003143//embryonic heart tube morphogenesis;GO:0001525//angiogenesis;GO:0009611//response to wounding gi|226437649|ref|NP_001139820.1|/0/endoglin isoform 3 precursor [Mus musculus] 17178 524 0.696666667 0.64 -0.122396631 Down 0.123528527 Fxyd3 FXYD domain-containing ion transport regulator 3 K13361|1|7e-38|158|mmu:17178|FXYD domain-containing ion transport regulator 3 GO:0031090//organelle membrane;GO:0034702//ion channel complex GO:0005253//anion channel activity;GO:0019899//enzyme binding GO:0015698//inorganic anion transport;GO:0019222//regulation of metabolic process gi|6678814|ref|NP_032583.1|/4.74742e-37/FXYD domain-containing ion transport regulator 3 precursor [Mus musculus] 71063 5630 0.713333333 0.776666667 0.122719158 Up 0.123528527 Zfp597 zinc finger protein 597 K09228|1|0.0|830|mmu:71063|KRAB domain-containing zinc finger protein - - - gi|84370272|ref|NP_001028331.2|/0/zinc finger protein 597 [Mus musculus] 11931 2590 159.6866667 161.7933333 0.018908306 Up 0.12330287 Atp1b1 "ATPase, Na+/K+ transporting, beta 1 polypeptide" K01540|1|6e-160|567|mmu:11931|sodium/potassium-transporting ATPase subunit beta GO:0005887//integral component of plasma membrane GO:0005488//binding;GO:0008556//potassium-transporting ATPase activity GO:0044763;GO:0002376//immune system process;GO:0007599//hemostasis;GO:0030001//metal ion transport;GO:0001701//in utero embryonic development;GO:0006950//response to stress gi|6753138|ref|NP_033851.1|/5.32481e-159/sodium/potassium-transporting ATPase subunit beta-1 [Mus musculus] 110454 961.74 158.0266667 155.92 -0.019362035 Down 0.12330287 Ly6a "lymphocyte antigen 6 complex, locus A" K06846|1|1e-58|229|mmu:110454|lymphocyte antigen 6 complex locus protein D/E/G6/H GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane - - "gi|148697524|gb|EDL29471.1|/3.3529e-63/lymphocyte antigen 6 complex, locus A, isoform CRA_b, partial [Mus musculus]" 20916 2108 166.9433333 168.9966667 0.017636308 Up 0.123284065 Sucla2 "succinate-Coenzyme A ligase, ADP-forming, beta subunit" K01900|1|0.0|879|mmu:20916|succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0004774//succinate-CoA ligase activity;GO:0032550 GO:0009060//aerobic respiration;GO:0006637//acyl-CoA metabolic process;GO:0043648//dicarboxylic acid metabolic process "gi|46849708|ref|NP_035636.1|/0/succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial precursor [Mus musculus]" 269344 1745 0.033333333 0.06 0.847996907 Up 0.123246455 Ell3 elongation factor RNA polymerase II-like 3 K15183|1|0.0|717|mmu:269344|RNA polymerase II elongation factor ELL GO:0031981//nuclear lumen;GO:0043234//protein complex GO:0044212//transcription regulatory region DNA binding "GO:0006366//transcription from RNA polymerase II promoter;GO:0001837//epithelial to mesenchymal transition;GO:0009968//negative regulation of signal transduction;GO:0010720//positive regulation of cell development;GO:0006915//apoptotic process;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0008284//positive regulation of cell proliferation" gi|35901198|ref|NP_666085.2|/0/RNA polymerase II elongation factor ELL3 [Mus musculus] 66805 1971 0.03 0.056666667 0.91753784 Up 0.123246455 Tspan1 tetraspanin 1 K17348|1|2e-112|409|mmu:66805|tetraspanin-1 GO:0005764//lysosome;GO:0031224//intrinsic component of membrane - - gi|19526840|ref|NP_598442.1|/1.33132e-111/tetraspanin-1 [Mus musculus] 69121 1478 0.04 0.07 0.807354922 Up 0.123246455 Chrdl2 chordin-like 2 K17280|1|0.0|891|mmu:69121|chordin-like protein 2 - GO:0005488//binding;GO:0005488//binding GO:0048869//cellular developmental process;GO:0030509//BMP signaling pathway;GO:0001501//skeletal system development;GO:0048869//cellular developmental process;GO:0030509//BMP signaling pathway;GO:0001501//skeletal system development gi|604723321|ref|NP_001278249.1|/0/chordin-like protein 2 isoform 1 [Mus musculus] 353204 2052 0.056666667 0.03 -0.91753784 Down 0.123246455 Aldoart1 "aldolase 1 A, retrogene 1" "K01623|1|0.0|807|mmu:353204|fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0005856//cytoskeleton GO:0005515//protein binding;GO:0016832//aldehyde-lyase activity;GO:0048029//monosaccharide binding GO:0022604//regulation of cell morphogenesis;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006007//glucose catabolic process;GO:0006936//muscle contraction;GO:0019725//cellular homeostasis gi|312922382|ref|NP_001186199.1|/0/aldolase 1 A retrogene 1 [Mus musculus] 67656 1427 0.073333333 0.04 -0.874469118 Down 0.123246455 4930548H24Rik RIKEN cDNA 4930548H24 gene K19603|1|6e-14|81.3|asn:102378924|mitogen-activated protein kinase 15 [EC:2.7.11.24];K16464|2|4e-10|68.6|ptg:102970946|centrosomal protein CEP250;K20283|3|2e-09|66.6|dmo:Dmoj_GI20507|golgin subfamily A member 4;K16767|4|2e-09|66.6|fch:102049593|centrosomal protein CEP112 - - - gi|21312838|ref|NP_080572.1|/0/uncharacterized protein LOC67656 [Mus musculus] 432516 3353 0.036666667 0.07 0.932885804 Up 0.123246455 Myo1a myosin IA K10356|1|0.0|2015|mmu:432516|myosin I GO:0043005//neuron projection;GO:0044297//cell body;GO:0005884//actin filament;GO:0016323//basolateral plasma membrane GO:0008092//cytoskeletal protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0051640//organelle localization;GO:0050954//sensory perception of mechanical stimulus;GO:0051017//actin filament bundle assembly;GO:0008104//protein localization;GO:0030031//cell projection assembly gi|124487037|ref|NP_001074688.1|/0/unconventional myosin-Ia [Mus musculus] 28194 1618 0.066666667 0.036666667 -0.862496476 Down 0.123246455 Apon apolipoprotein N - - - - gi|19527214|ref|NP_598757.1|/5.8112e-139/apolipoprotein N precursor [Mus musculus] 16691 1805 0.033333333 0.06 0.847996907 Up 0.123246455 Krt8 keratin 8 "K07605|1|0.0|776|xla:100037087|type II keratin, basic" GO:0031674//I band;GO:0034399//nuclear periphery;GO:0005882//intermediate filament;GO:0005886//plasma membrane GO:0005515//protein binding GO:0012501//programmed cell death;GO:0030239//myofibril assembly;GO:0019221//cytokine-mediated signaling pathway;GO:0001892//embryonic placenta development;GO:0006950//response to stress;GO:0009607//response to biotic stimulus "gi|114145561|ref|NP_112447.2|/0/keratin, type II cytoskeletal 8 [Mus musculus]" 74041 3450 0.043333333 0.076666667 0.823122238 Up 0.123246455 Ddias DNA damage-induced apoptosis suppressor - GO:0043231//intracellular membrane-bounded organelle - GO:0009411//response to UV;GO:0010332//response to gamma radiation;GO:0007050//cell cycle arrest;GO:0048534//hematopoietic or lymphoid organ development;GO:0033194//response to hydroperoxide;GO:0033554//cellular response to stress;GO:0034097//response to cytokine;GO:0007281//germ cell development;GO:0043066//negative regulation of apoptotic process gi|124430773|ref|NP_001074464.1|/0/DNA damage-induced apoptosis suppressor protein [Mus musculus] 209601 2009 0.056666667 0.03 -0.91753784 Down 0.123246455 Erich3 glutamate rich 3 - - - - gi|148877986|gb|AAI45841.1|/0/4922501L14Rik protein [Mus musculus] 80910 1611 0.066666667 0.036666667 -0.862496476 Down 0.123246455 Gpr84 G protein-coupled receptor 84 K08421|1|0.0|711|mmu:80910|G protein-coupled receptor 84 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|568993661|ref|XP_006521617.1|/0/PREDICTED: G-protein coupled receptor 84 isoform X1 [Mus musculus] 71263 2302 0.056666667 0.03 -0.91753784 Down 0.123246455 Mro maestro - GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - - gi|569004517|ref|XP_006526313.1|/2.54842e-167/PREDICTED: protein maestro isoform X2 [Mus musculus] 68678 1761 0.063333333 0.033333333 -0.925999419 Down 0.123246455 Smtnl1 smoothelin-like 1 K10314|1|9e-37|157|bacu:103002192|F-box protein 39;K19948|2|1e-18|97.1|hmg:100202236|MICAL-like protein;K05699|3|2e-18|96.7|hro:HELRODRAFT_93275|actinin alpha - - - - 230822 1448 0.073333333 0.04 -0.874469118 Down 0.123246455 Ncmap noncompact myelin associated protein - GO:0016021//integral component of membrane;GO:0033267;GO:0043218//compact myelin;GO:0016021//integral component of membrane;GO:0033267;GO:0043218//compact myelin;GO:0016021//integral component of membrane;GO:0033267;GO:0043218//compact myelin;GO:0016021//integral component of membrane;GO:0033267;GO:0043218//compact myelin;GO:0016021//integral component of membrane;GO:0033267;GO:0043218//compact myelin;GO:0016021//integral component of membrane;GO:0033267;GO:0043218//compact myelin GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0031641//regulation of myelination;GO:0022011//myelination in peripheral nervous system;GO:0031641//regulation of myelination;GO:0022011//myelination in peripheral nervous system;GO:0031641//regulation of myelination;GO:0022011//myelination in peripheral nervous system;GO:0031641//regulation of myelination;GO:0022011//myelination in peripheral nervous system;GO:0031641//regulation of myelination;GO:0022011//myelination in peripheral nervous system;GO:0031641//regulation of myelination;GO:0022011//myelination in peripheral nervous system "gi|148698035|gb|EDL29982.1|/2.49749e-48/RIKEN cDNA A330049M08, isoform CRA_b [Mus musculus]" 242259 4098 0.07 0.036666667 -0.932885804 Down 0.123246455 Slc44a5 "solute carrier family 44, member 5" "K15377|1|0.0|1385|mmu:242259|solute carrier family 44 (choline transporter-like protein), member 2/4/5" GO:0031224//intrinsic component of membrane - - gi|134053957|ref|NP_001074732.1|/0/choline transporter-like protein 5 [Mus musculus] 320495 4060.84 0.06 0.033333333 -0.847996907 Down 0.123246455 Ipcef1 interaction protein for cytohesin exchange factors 1 K17536|1|9e-52|208|cmk:103186444|connector enhancer of kinase suppressor of Ras 2 GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0005515//protein binding;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0005515//protein binding - gi|74182011|dbj|BAE34075.1|/0/unnamed protein product [Mus musculus] 268288 1892 0.056666667 0.03 -0.91753784 Down 0.123246455 Samd3 sterile alpha motif domain containing 3 - - - - gi|568965414|ref|XP_006512804.1|/0/PREDICTED: sterile alpha motif domain-containing protein 3 isoform X1 [Mus musculus] 219148 4252 0.03 0.056666667 0.91753784 Up 0.123246455 Fam167a "family with sequence similarity 167, member A" - - - - - 11447 3003 0.036666667 0.066666667 0.862496476 Up 0.123246455 Chrnd "cholinergic receptor, nicotinic, delta polypeptide" K04816|1|0.0|951|mmu:11447|nicotinic acetylcholine receptor delta GO:0097060//synaptic membrane;GO:0005887//integral component of plasma membrane GO:0042165//neurotransmitter binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0006811//ion transport;GO:0050879//multicellular organismal movement;GO:0007519//skeletal muscle tissue development;GO:0006873//cellular ion homeostasis gi|110225335|ref|NP_067611.2|/0/acetylcholine receptor subunit delta precursor [Mus musculus] 19142 2607 0.043333333 0.076666667 0.823122238 Up 0.123246455 Prss12 "protease, serine 12 neurotrypsin (motopsin)" K09624|1|0.0|1520|mmu:19142|neurotrypsin [EC:3.4.21.-] GO:0031982//vesicle;GO:0033267;GO:0044420//extracellular matrix component;GO:0016020//membrane GO:0004175//endopeptidase activity;GO:0038024//cargo receptor activity GO:0016485//protein processing;GO:0016192//vesicle-mediated transport gi|6679485|ref|NP_032965.1|/0/neurotrypsin precursor [Mus musculus] 14799 5382 0.073333333 0.04 -0.874469118 Down 0.123246455 Gria1 "glutamate receptor, ionotropic, AMPA1 (alpha 1)" K05197|1|0.0|1679|mmu:14799|glutamate receptor 1 GO:0030313//cell envelope;GO:0008328//ionotropic glutamate receptor complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0044297//cell body;GO:0032589//neuron projection membrane;GO:0031090//organelle membrane;GO:0005768//endosome;GO:0030136//clathrin-coated vesicle;GO:0030313//cell envelope;GO:0008328//ionotropic glutamate receptor complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0044297//cell body;GO:0032589//neuron projection membrane;GO:0031090//organelle membrane;GO:0005768//endosome;GO:0030136//clathrin-coated vesicle;GO:0030313//cell envelope;GO:0008328//ionotropic glutamate receptor complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0044297//cell body;GO:0032589//neuron projection membrane;GO:0031090//organelle membrane;GO:0005768//endosome;GO:0030136//clathrin-coated vesicle GO:0051020//GTPase binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004970//ionotropic glutamate receptor activity;GO:0017022//myosin binding;GO:0031690//adrenergic receptor binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0019900//kinase binding;GO:0051020//GTPase binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004970//ionotropic glutamate receptor activity;GO:0017022//myosin binding;GO:0031690//adrenergic receptor binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0019900//kinase binding;GO:0051020//GTPase binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004970//ionotropic glutamate receptor activity;GO:0017022//myosin binding;GO:0031690//adrenergic receptor binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0019900//kinase binding GO:0070848//response to growth factor;GO:0014075//response to amine;GO:0007270//neuron-neuron synaptic transmission;GO:0001508//action potential;GO:0007417//central nervous system development;GO:0007613//memory;GO:0006898//receptor-mediated endocytosis;GO:0009636//response to toxic substance;GO:0043627//response to estrogen;GO:0010038//response to metal ion;GO:0044765//single-organism transport;GO:0009628//response to abiotic stimulus;GO:0043200//response to amino acid;GO:0050804//modulation of synaptic transmission;GO:0043331//response to dsRNA;GO:0007215//glutamate receptor signaling pathway;GO:0032870//cellular response to hormone stimulus;GO:0070848//response to growth factor;GO:0014075//response to amine;GO:0007270//neuron-neuron synaptic transmission;GO:0001508//action potential;GO:0007417//central nervous system development;GO:0007613//memory;GO:0006898//receptor-mediated endocytosis;GO:0009636//response to toxic substance;GO:0043627//response to estrogen;GO:0010038//response to metal ion;GO:0044765//single-organism transport;GO:0009628//response to abiotic stimulus;GO:0043200//response to amino acid;GO:0050804//modulation of synaptic transmission;GO:0043331//response to dsRNA;GO:0007215//glutamate receptor signaling pathway;GO:0032870//cellular response to hormone stimulus;GO:0070848//response to growth factor;GO:0014075//response to amine;GO:0007270//neuron-neuron synaptic transmission;GO:0001508//action potential;GO:0007417//central nervous system development;GO:0007613//memory;GO:0006898//receptor-mediated endocytosis;GO:0009636//response to toxic substance;GO:0043627//response to estrogen;GO:0010038//response to metal ion;GO:0044765//single-organism transport;GO:0009628//response to abiotic stimulus;GO:0043200//response to amino acid;GO:0050804//modulation of synaptic transmission;GO:0043331//response to dsRNA;GO:0007215//glutamate receptor signaling pathway;GO:0032870//cellular response to hormone stimulus gi|227246|prf||1617121A/0/Glu receptor 1 667118 5007 0.07 0.04 -0.807354922 Down 0.123246455 Zbed6 "zinc finger, BED type containing 6" "K14312|1|1e-12|79.3|hmg:100212106|nuclear pore complex protein Nup155;K16547|2|1e-08|65.9|hmg:100209833|protein NEDD1;K14864|3|8e-08|63.2|aqu:100636976|tRNA (cytidine32/guanosine34-2'-O)-methyltransferase [EC:2.1.1.205];K06496|4|8e-08|63.2|lcm:102355208|selectin, platele" - - - - 19051 1738 0.06 0.033333333 -0.847996907 Down 0.123246455 Ppp1r17 "protein phosphatase 1, regulatory subunit 17" K08067|1|4e-87|324|mmu:19051|protein phosphatase 1 regulatory subunit 17 GO:0044444//cytoplasmic part GO:0004864//protein phosphatase inhibitor activity GO:0035556//intracellular signal transduction;GO:0006464//cellular protein modification process;GO:0007399//nervous system development;GO:0035303//regulation of dephosphorylation;GO:0044092//negative regulation of molecular function gi|6755148|ref|NP_035283.1|/3.66894e-86/protein phosphatase 1 regulatory subunit 17 [Mus musculus] 12661 7751 0.07 0.04 -0.807354922 Down 0.123246455 Chl1 cell adhesion molecule L1-like K06758|1|0.0|2394|mmu:12661|L1 cell adhesion molecule like protein - - - - 229333 2789 0.036666667 0.07 0.932885804 Up 0.123246455 C130079G13Rik RIKEN cDNA C130079G13 gene K14350|1|0.0|645|rno:295073|arylacetamide deacetylase-like 2 [EC:3.1.1.-] - - - gi|148703421|gb|EDL35368.1|/0/mCG132335 [Mus musculus] 633285 3586 0.056666667 0.03 -0.91753784 Down 0.123246455 Rbm46 RNA binding motif protein 46 K13161|1|2e-87|327|amj:102557895|heterogeneous nuclear ribonucleoprotein R - - - gi|461496486|ref|NP_001264099.1|/0/probable RNA-binding protein 46 [Mus musculus] 71981 1621 0.066666667 0.036666667 -0.862496476 Down 0.123246455 Tdrd12 tudor domain containing 12 K18409|1|0.0|835|mmu:71981|ATP-dependent RNA helicase TDRD12 [EC:3.6.4.13] - - - gi|62485058|dbj|BAD95488.1|/0/ES cell associated transcript 8 [Mus musculus] 19328 2010 108.9866667 110.88 0.024847515 Up 0.123096017 Rab12 "RAB12, member RAS oncogene family" K07907|1|6e-117|424|mmu:19328|Ras-related protein Rab-12 "GO:0005764//lysosome;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0012505//endomembrane system;GO:0010008//endosome membrane" GO:0032550 GO:0035556//intracellular signal transduction;GO:0007041//lysosomal transport;GO:0045184//establishment of protein localization;GO:0030163//protein catabolic process gi|106507168|ref|NP_077768.2|/5.34653e-116/ras-related protein Rab-12 [Mus musculus] 69659 879 1.116666667 1.05 -0.088809267 Down 0.123049005 2310069G16Rik RIKEN cDNA 2310069G16 gene - GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0019905//syntaxin binding;GO:0015631//tubulin binding GO:0050796//regulation of insulin secretion "gi|148676787|gb|EDL08734.1|/8.49182e-25/mCG146092, partial [Mus musculus]" 13178 3057 1.073333333 1.14 0.086935637 Up 0.123049005 Dck deoxycytidine kinase K00893|1|2e-150|535|mmu:13178|deoxycitidine kinase [EC:2.7.1.74] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0032550;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0001884;GO:0019136//deoxynucleoside kinase activity GO:0009117//nucleotide metabolic process;GO:0046125 gi|6681141|ref|NP_031858.1|/2.07679e-149/deoxycytidine kinase [Mus musculus] 13384 2860 1.11 1.043333333 -0.08935952 Down 0.123049005 Mpp3 "membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)" K06091|1|5e-99|365|crg:105335272|MAGUK p55 subfamily member 5 GO:0044464;GO:0016021//integral component of membrane "GO:0019904//protein domain specific binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0006796//phosphate-containing compound metabolic process;GO:0007154//cell communication gi|118026923|ref|NP_031889.2|/0/MAGUK p55 subfamily member 3 [Mus musculus] 625585 1927 1.03 1.096666667 0.090480746 Up 0.123049005 Gm6602 predicted gene 6602 K11290|1|4e-09|65.9|rno:317165|template-activating factor I - - - "gi|148670062|gb|EDL02009.1|/8.26574e-34/mCG144525, partial [Mus musculus]" 73078 1596 120.5433333 118.7466667 -0.021664849 Down 0.1230302 Pmpcb peptidase (mitochondrial processing) beta K17732|1|0.0|961|mmu:73078|mitochondrial-processing peptidase subunit beta [EC:3.4.24.64] GO:0019866//organelle inner membrane;GO:0044429 GO:0043169//cation binding;GO:0004175//endopeptidase activity GO:0006626//protein targeting to mitochondrion;GO:0019538//protein metabolic process gi|95113671|ref|NP_082707.1|/0/mitochondrial-processing peptidase subunit beta precursor [Mus musculus] 23936 3952 115.3633333 113.6266667 -0.0218833 Down 0.122964384 Lynx1 Ly6/neurotoxin 1 K06846|1|2e-26|124|oaa:100082309|lymphocyte antigen 6 complex locus protein D/E/G6/H GO:0016020//membrane;GO:0042995//cell projection GO:0016248//channel inhibitor activity;GO:0030547//receptor inhibitor activity GO:0007268//chemical synaptic transmission gi|7106349|ref|NP_035968.1|/7.49858e-54/ly-6/neurotoxin-like protein 1 precursor [Mus musculus] 231580 4798 11.20333333 10.98666667 -0.0281743 Down 0.122917372 Gak cyclin G associated kinase K08855|1|0.0|2453|mmu:231580|cyclin G-associated kinase [EC:2.7.11.1] GO:0005924//cell-substrate adherens junction;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005924//cell-substrate adherens junction;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0005924//cell-substrate adherens junction;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0032550;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0032550;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0032550 GO:0044763;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0044763;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0044763;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process "gi|148688156|gb|EDL20103.1|/0/cyclin G associated kinase, isoform CRA_e, partial [Mus musculus]" 20334 4108 10.76666667 10.99 0.029619722 Up 0.122917372 Sec23a "SEC23 homolog A, COPII coat complex component" K14006|1|0.0|1560|rno:58817|protein transport protein SEC23 GO:0012507//ER to Golgi transport vesicle membrane GO:0046914//transition metal ion binding GO:0016482//cytosolic transport;GO:0015031//protein transport gi|67906177|ref|NP_033173.2|/0/protein transport protein Sec23A [Mus musculus] 217951 3707 0.193333333 0.23 0.250543462 Up 0.122917372 Tmem196 transmembrane protein 196 - GO:0031224//intrinsic component of membrane - - gi|537170289|gb|ERE74106.1|/5.50423e-75/transmembrane protein [Cricetulus griseus] 27267 3063.6 9.54 9.763333333 0.033384521 Up 0.122917372 Cars cysteinyl-tRNA synthetase K01883|1|0.0|1597|mmu:27267|cysteinyl-tRNA synthetase [EC:6.1.1.16] - - - "gi|148747198|ref|NP_038770.3|/0/cysteine--tRNA ligase, cytoplasmic isoform 1 [Mus musculus]" 71517 3578 9.51 9.733333333 0.033488622 Up 0.122917372 9030624J02Rik RIKEN cDNA 9030624J02 gene - GO:0031224//intrinsic component of membrane - - gi|270047485|ref|NP_082091.3|/0/UPF0505 protein C16orf62 homolog [Mus musculus] 226517 5856.57 11.39 11.16666667 -0.028569152 Down 0.122917372 Smg7 "Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)" K14409|1|0.0|1883|mmu:226517|protein SMG7 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0019903//protein phosphatase binding;GO:0019903//protein phosphatase binding;GO:0019903//protein phosphatase binding - gi|53828718|ref|NP_001005507.1|/0/protein SMG7 isoform 3 [Mus musculus] 269019 3765 0.196666667 0.233333333 0.246639968 Up 0.122917372 Stk32a serine/threonine kinase 32A K08793|1|0.0|759|mmu:269019|serine/threonine kinase 32 [EC:2.7.11.1] - GO:0043169//cation binding;GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|30520199|ref|NP_848864.1|/0/serine/threonine-protein kinase 32A [Mus musculus] 74088 1513 0.196666667 0.233333333 0.246639968 Up 0.122917372 Them7 thioesterase superfamily member 7 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|21311853|ref|NP_083023.1|/3.03583e-118/uncharacterized protein LOC74088 isoform 1 [Mus musculus] 215194 2625 11.91333333 12.13666667 0.026795106 Up 0.122917372 Kri1 KRI1 homolog K14786|1|0.0|1106|mmu:215194|protein KRI1 - - - - 11964 3946 4.57 4.43 -0.044887467 Down 0.122842153 Atp6v1a "ATPase, H+ transporting, lysosomal V1 subunit A" K02145|1|0.0|1198|mmu:11964|V-type H+-transporting ATPase subunit A [EC:3.6.3.14] GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0033176//proton-transporting V-type ATPase complex;GO:0042995//cell projection;GO:0044444//cytoplasmic part GO:0032550;GO:0019829//cation-transporting ATPase activity "GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0009150//purine ribonucleotide metabolic process" gi|31560731|ref|NP_031534.2|/0/V-type proton ATPase catalytic subunit A [Mus musculus] 27410 6514.57 5.013333333 4.87 -0.041848389 Down 0.122842153 Abca3 "ATP-binding cassette, sub-family A (ABC1), member 3" "K05643|1|0.0|3197|mmu:27410|ATP-binding cassette, subfamily A (ABC1), member 3" GO:0031224//intrinsic component of membrane;GO:0097232//lamellar body membrane;GO:0031224//intrinsic component of membrane;GO:0097232//lamellar body membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0009154//purine ribonucleotide catabolic process;GO:0051234//establishment of localization;GO:0009154//purine ribonucleotide catabolic process;GO:0051234//establishment of localization "gi|148690365|gb|EDL22312.1|/0/ATP-binding cassette, sub-family A (ABC1), member 3, isoform CRA_b, partial [Mus musculus]" 68327 1224 5.283333333 5.42 0.036844417 Up 0.122842153 Tsr3 TSR3 20S rRNA accumulation K09140|1|7e-162|572|mmu:68327|pre-rRNA-processing protein TSR3 - - GO:0042254//ribosome biogenesis;GO:0042254//ribosome biogenesis "gi|148669247|gb|EDL01194.1|/6.8582e-176/RIKEN cDNA 0610007P22, isoform CRA_a, partial [Mus musculus]" 68713 699.15 4.863333333 5.006666667 0.04190493 Up 0.122842153 Ifitm1 interferon induced transmembrane protein 1 K19831|1|3e-46|186|mmu:68713|interferon induced transmembrane protein 1;K06566|3|2e-37|157|mmu:74482|interferon induced transmembrane protein GO:0005770//late endosome;GO:0031224//intrinsic component of membrane;GO:0005770//late endosome;GO:0031224//intrinsic component of membrane - GO:0046718//viral entry into host cell;GO:0001649//osteoblast differentiation;GO:0051707//response to other organism;GO:0019079//viral genome replication;GO:0008283//cell proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0002252;GO:0009952//anterior/posterior pattern specification;GO:0006952//defense response;GO:0016477//cell migration;GO:0046718//viral entry into host cell;GO:0001649//osteoblast differentiation;GO:0051707//response to other organism;GO:0019079//viral genome replication;GO:0008283//cell proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0002252;GO:0009952//anterior/posterior pattern specification;GO:0006952//defense response;GO:0016477//cell migration gi|163310729|ref|NP_081096.3|/2.51098e-45/interferon-induced transmembrane protein 1 [Mus musculus] 328977 5512 4.97 4.826666667 -0.042218655 Down 0.122842153 Zfp532 zinc finger protein 532 K19325|1|0.0|1012|amj:102558899|zinc finger protein 592 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|46402263|ref|NP_997138.1|/0/zinc finger protein 532 [Mus musculus] 14696 2751 4.963333333 4.826666667 -0.040282151 Down 0.122842153 Gnb4 "guanine nucleotide binding protein (G protein), beta 4" K04538|1|0.0|670|mmu:14696|guanine nucleotide-binding protein subunit beta-4 GO:0044464;GO:0016020//membrane GO:0060089 GO:0033762//response to glucagon;GO:0007166//cell surface receptor signaling pathway;GO:0015980//energy derivation by oxidation of organic compounds gi|31542899|ref|NP_038559.2|/0/guanine nucleotide-binding protein subunit beta-4 [Mus musculus] 20841 3013 4.566666667 4.426666667 -0.044920747 Down 0.122842153 Zfp143 zinc finger protein 143 K09228|1|4e-55|219|mmu:100043915|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|852785822|ref|XP_012884256.1|/0/PREDICTED: zinc finger protein 143 isoform X2 [Dipodomys ordii] 71728 4474 4.533333333 4.673333333 0.043879698 Up 0.122842153 Stk11ip serine/threonine kinase 11 interacting protein - GO:0044424 GO:0019900//kinase binding GO:0033036 gi|169808413|ref|NP_082162.3|/0/serine/threonine-protein kinase 11-interacting protein [Mus musculus] 381511 4198 5.63 5.773333333 0.036269602 Up 0.122842153 Pdp1 pyruvate dehyrogenase phosphatase catalytic subunit 1 K01102|1|0.0|1191|cge:100761381|pyruvate dehydrogenase phosphatase [EC:3.1.3.43] GO:0044429;GO:0044429;GO:0044429;GO:0044429;GO:0044429 GO:0046872//metal ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding GO:0006470//protein dephosphorylation;GO:0044093;GO:0006470//protein dephosphorylation;GO:0044093;GO:0006470//protein dephosphorylation;GO:0044093;GO:0006470//protein dephosphorylation;GO:0044093;GO:0006470//protein dephosphorylation;GO:0044093 "gi|564350402|ref|XP_006237969.1|/0/PREDICTED: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial isoform X2 [Rattus norvegicus]" 227656 2354 5.52 5.656666667 0.035283892 Up 0.122842153 Rexo4 "REX4, 3'-5' exonuclease" K18327|1|0.0|704|mmu:227656|RNA exonuclease 4 [EC:3.1.-.-] GO:0031981//nuclear lumen GO:0004518//nuclease activity - gi|76563952|ref|NP_997117.2|/0/RNA exonuclease 4 [Mus musculus] 100561 2720 5.116666667 5.26 0.03985855 Up 0.122842153 Slc15a4 "solute carrier family 15, member 4" "K14638|1|0.0|868|mmu:100561|solute carrier family 15 (peptide/histidine transporter), member 3/4" GO:0016020//membrane GO:0008324//cation transmembrane transporter activity GO:0015833//peptide transport;GO:0006812//cation transport gi|19527112|ref|NP_598656.1|/0/solute carrier family 15 member 4 [Mus musculus] 66508 1201 106.4133333 108.07 0.022287161 Up 0.12283275 Lamtor1 "late endosomal/lysosomal adaptor, MAPK and MTOR activator 1" K20397|1|2e-85|318|cge:100750343|ragulator complex protein LAMTOR1 GO:0005764//lysosome;GO:0031902//late endosome membrane;GO:0044425 GO:0030695//GTPase regulator activity;GO:0005515//protein binding GO:0051640//organelle localization;GO:0040007//growth;GO:0001881//receptor recycling;GO:0007033//vacuole organization;GO:0019218//regulation of steroid metabolic process;GO:0000165//MAPK cascade;GO:0009967//positive regulation of signal transduction;GO:0008104//protein localization;GO:0043200//response to amino acid;GO:0032374//regulation of cholesterol transport;GO:0055092//sterol homeostasis gi|242332593|ref|NP_079881.2|/2.06193e-84/ragulator complex protein LAMTOR1 [Mus musculus] 14707 535 131.4666667 133.13 0.018138659 Up 0.12283275 Gng5 "guanine nucleotide binding protein (G protein), gamma 5" K04542|1|2e-23|110|pale:102879439|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 GO:0043231//intracellular membrane-bounded organelle;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane GO:0017111//nucleoside-triphosphatase activity;GO:0060089 GO:0007166//cell surface receptor signaling pathway;GO:0015980//energy derivation by oxidation of organic compounds;GO:0007267//cell-cell signaling;GO:0033762//response to glucagon;GO:0009154//purine ribonucleotide catabolic process gi|71089955|gb|AAZ23832.1|/1.18492e-22/guanine nucleotide binding protein gamma 5 [Rattus norvegicus] 78923 3882 0.063333333 0.036666667 -0.788495895 Down 0.122813946 Chsy3 chondroitin sulfate synthase 3 K13499|1|0.0|1595|mmu:78923|chondroitin sulfate synthase [EC:2.4.1.175 2.4.1.226] GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane GO:0015020//glucuronosyltransferase activity;GO:0043169//cation binding;GO:0008376//acetylgalactosaminyltransferase activity - gi|60360176|dbj|BAD90307.1|/0/mKIAA4168 protein [Mus musculus] 14806 4785 0.04 0.066666667 0.736965594 Up 0.122813946 Grik2 "glutamate receptor, ionotropic, kainate 2 (beta 2)" "K05202|1|0.0|1770|mmu:14806|glutamate receptor, ionotropic kainate 2" GO:0008328//ionotropic glutamate receptor complex;GO:0097060//synaptic membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0033267;GO:0008328//ionotropic glutamate receptor complex;GO:0097060//synaptic membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0033267 GO:0044389//ubiquitin-like protein ligase binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004970//ionotropic glutamate receptor activity;GO:0044390//ubiquitin-like protein conjugating enzyme binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004970//ionotropic glutamate receptor activity;GO:0044390//ubiquitin-like protein conjugating enzyme binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding "GO:0060078//regulation of postsynaptic membrane potential;GO:0070997//neuron death;GO:0001508//action potential;GO:0043066//negative regulation of apoptotic process;GO:0048168//regulation of neuronal synaptic plasticity;GO:0072657//protein localization to membrane;GO:0015031//protein transport;GO:0002209//behavioral defense response;GO:0035249//synaptic transmission, glutamatergic;GO:0007254//JNK cascade;GO:0051899//membrane depolarization;GO:0043065//positive regulation of apoptotic process;GO:0044765//single-organism transport;GO:0031338//regulation of vesicle fusion;GO:0007215//glutamate receptor signaling pathway;GO:0006875//cellular metal ion homeostasis;GO:0060078//regulation of postsynaptic membrane potential;GO:0070997//neuron death;GO:0001508//action potential;GO:0043066//negative regulation of apoptotic process;GO:0048168//regulation of neuronal synaptic plasticity;GO:0072657//protein localization to membrane;GO:0015031//protein transport;GO:0002209//behavioral defense response;GO:0035249//synaptic transmission, glutamatergic;GO:0007254//JNK cascade;GO:0051899//membrane depolarization;GO:0043065//positive regulation of apoptotic process;GO:0044765//single-organism transport;GO:0031338//regulation of vesicle fusion;GO:0007215//glutamate receptor signaling pathway;GO:0006875//cellular metal ion homeostasis" "gi|163659881|ref|NP_001104738.1|/0/glutamate receptor ionotropic, kainate 2 isoform 1 precursor [Mus musculus]" 72555 4796 0.05 0.083333333 0.736965594 Up 0.122813946 Shisa9 shisa family member 9 - - - - - 545649 1462 0.08 0.046666667 -0.777607579 Down 0.122813946 Gm13276 predicted gene 13276 K05414|1|7e-38|160|cge:100763520|interferon alpha GO:0044421 GO:0005102//receptor binding GO:0007166//cell surface receptor signaling pathway;GO:0030098//lymphocyte differentiation;GO:0002252;GO:0007049//cell cycle;GO:0012501//programmed cell death gi|148238094|ref|NP_001079001.1|/4.19497e-101/interferon zeta-like precursor [Mus musculus] 17059 2632 0.04 0.066666667 0.736965594 Up 0.122813946 Klrb1c killer cell lectin-like receptor subfamily B member 1C K06543|1|1e-160|569|mmu:17059|killer cell lectin-like receptor subfamily B GO:0009986//cell surface;GO:0016021//integral component of membrane GO:0042802//identical protein binding GO:0046649//lymphocyte activation;GO:0001912//positive regulation of leukocyte mediated cytotoxicity gi|229577432|ref|NP_001153376.1|/6.88075e-162/killer cell lectin-like receptor subfamily B member 1C isoform 1 [Mus musculus] 269610 9375 0.046666667 0.08 0.777607579 Up 0.122813946 Chd5 chromodomain helicase DNA binding protein 5 K14435|1|0.0|3191|mmu:269610|chromodomain-helicase-DNA-binding protein 5 [EC:3.6.4.12] - - - gi|124487025|ref|NP_001074845.1|/0/chromodomain-helicase-DNA-binding protein 5 isoform 1 [Mus musculus] 66729 1514 0.063333333 0.036666667 -0.788495895 Down 0.122813946 Ankrd61 ankyrin repeat domain 61 K10380|1|5e-21|105|dsi:Dsimw501_GD27865|ankyrin - - - "gi|148687089|gb|EDL19036.1|/0/RIKEN cDNA 4921520G13, isoform CRA_b, partial [Mus musculus]" 385354 4647 0.063333333 0.036666667 -0.788495895 Down 0.122813946 Frmd7 FERM domain containing 7 "K17477|1|6e-108|395|gfr:102032840|FERM, RhoGEF and pleckstrin domain-containing protein 1" GO:0043005//neuron projection;GO:0043232;GO:0044297//cell body - GO:0031175//neuron projection development gi|298358799|ref|NP_001177261.1|/0/FERM domain-containing protein 7 [Mus musculus] 68753 1287 0.043333333 0.073333333 0.7589919 Up 0.122813946 Mybphl myosin binding protein H-like "K12568|1|7e-108|393|tgu:100220915|myosin-binding protein C, cardiac-type" - - - gi|74316017|ref|NP_081107.1|/0/myosin-binding protein H-like [Mus musculus] 71854 1681 0.036666667 0.063333333 0.788495895 Up 0.122813946 Dpep3 dipeptidase 3 K01273|1|0.0|886|mmu:71854|membrane dipeptidase [EC:3.4.13.19] GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0008238//exopeptidase activity;GO:0008237//metallopeptidase activity GO:0019538//protein metabolic process;GO:0007126//meiotic nuclear division gi|21313683|ref|NP_082236.1|/0/dipeptidase 3 precursor [Mus musculus] 75345 3977 0.04 0.066666667 0.736965594 Up 0.122813946 Slamf7 SLAM family member 7 K06733|1|0.0|671|mmu:75345|SLAM family member 7 GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0030101//natural killer cell activation "gi|148707114|gb|EDL39061.1|/0/SLAM family member 7, isoform CRA_b, partial [Mus musculus]" 75243 1267 0.046666667 0.08 0.777607579 Up 0.122813946 4930549C15Rik RIKEN cDNA 4930549C15 gene - - - - - 386753 2995 0.083333333 0.05 -0.736965594 Down 0.122813946 Dbpht2 DNA binding protein with his-thr domain - - - - gi|38524610|ref|NP_942566.1|/4.21493e-54/DNA binding protein with his-thr domain [Mus musculus] 208677 2283 0.066666667 0.04 -0.736965594 Down 0.122813946 Creb3l3 cAMP responsive element binding protein 3-like 3 K09048|1|0.0|911|mmu:208677|cyclic AMP-responsive element-binding protein 3 GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0031090//organelle membrane GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0035966//response to topologically incorrect protein" gi|21703728|ref|NP_663340.1|/0/cyclic AMP-responsive element-binding protein 3-like protein 3 [Mus musculus] 211651 4780 0.04 0.066666667 0.736965594 Up 0.122813946 Fancd2 "Fanconi anemia, complementation group D2" K10891|1|0.0|2581|mmu:211651|fanconi anemia group D2 protein GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome - GO:0007127//meiosis I;GO:0006259//DNA metabolic process;GO:0032502//developmental process;GO:0033554//cellular response to stress;GO:0010212//response to ionizing radiation;GO:0019953//sexual reproduction gi|282721083|ref|NP_001028416.2|/0/Fanconi anemia group D2 protein homolog [Mus musculus] 17123 1420 0.04 0.066666667 0.736965594 Up 0.122813946 Madcam1 mucosal vascular addressin cell adhesion molecule 1 K06779|1|0.0|721|mmu:17123|mucosal vascular addressin cell adhesion molecule 1 GO:0031224//intrinsic component of membrane - GO:0002376//immune system process;GO:0007155//cell adhesion;GO:0044767//single-organism developmental process;GO:0009913//epidermal cell differentiation gi|145386541|ref|NP_038619.2|/0/mucosal addressin cell adhesion molecule 1 precursor [Mus musculus] 108078 2957 0.05 0.083333333 0.736965594 Up 0.122813946 Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 K08763|1|7e-76|288|mmu:108078|oxidised low-density lipoprotein receptor 1 GO:0016020//membrane;GO:0019898//extrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0019898//extrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0030228//lipoprotein particle receptor activity;GO:0005488//binding;GO:0030228//lipoprotein particle receptor activity;GO:0005488//binding;GO:0030228//lipoprotein particle receptor activity GO:0019538//protein metabolic process;GO:0016337//single organismal cell-cell adhesion;GO:0006952//defense response;GO:0000302//response to reactive oxygen species;GO:0019538//protein metabolic process;GO:0016337//single organismal cell-cell adhesion;GO:0006952//defense response;GO:0000302//response to reactive oxygen species;GO:0019538//protein metabolic process;GO:0016337//single organismal cell-cell adhesion;GO:0006952//defense response;GO:0000302//response to reactive oxygen species gi|666875863|ref|NP_001288025.1|/1.61693e-82/oxidized low-density lipoprotein receptor 1 isoform 2 [Mus musculus] 68725 2578 0.043333333 0.073333333 0.7589919 Up 0.122813946 1110032F04Rik RIKEN cDNA 1110032F04 gene K19928|1|1e-06|58.2|xma:102216634|zona pellucida sperm-binding protein 3 - - - gi|269847632|ref|NP_001161468.1|/1.16767e-73/uncharacterized membrane protein C3orf80 homolog precursor [Mus musculus] 19353 2284 114.5333333 116.09 0.019476168 Up 0.122691715 Rac1 RAS-related C3 botulinum substrate 1 K04392|1|4e-96|355|dre:327204|Ras-related C3 botulinum toxin substrate 1 GO:0019898//extrinsic component of membrane;GO:0012505//endomembrane system;GO:0044459;GO:0048770;GO:0001726//ruffle GO:0019900//kinase binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017016//Ras GTPase binding "GO:0021843;GO:0050688//regulation of defense response to virus;GO:0051641//cellular localization;GO:0001894//tissue homeostasis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044764;GO:0016358//dendrite development;GO:0035567//non-canonical Wnt signaling pathway;GO:0006911//phagocytosis, engulfment;GO:0001667//ameboidal-type cell migration;GO:0006970//response to osmotic stress;GO:0006898//receptor-mediated endocytosis;GO:0000904//cell morphogenesis involved in differentiation;GO:0030595//leukocyte chemotaxis;GO:0042743//hydrogen peroxide metabolic process;GO:0007599//hemostasis;GO:0010591//regulation of lamellipodium assembly;GO:0000768//syncytium formation by plasma membrane fusion;GO:0031589//cell-substrate adhesion;GO:0006260//DNA replication;GO:0042472//inner ear morphogenesis;GO:0034330;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0030041//actin filament polymerization;GO:0007266//Rho protein signal transduction;GO:0001818//negative regulation of cytokine production;GO:0012501//programmed cell death;GO:0021795//cerebral cortex cell migration;GO:0031294//lymphocyte costimulation" "gi|147906150|ref|NP_001089332.1|/3.57403e-95/ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) [Xenopus laevis]" 21854 917 133.08 131.56 -0.016572858 Down 0.122663507 Timm17a translocase of inner mitochondrial membrane 17a K17795|1|4e-64|247|mmu:21854|mitochondrial import inner membrane translocase subunit TIM17 GO:0031304//intrinsic component of mitochondrial inner membrane GO:0005515//protein binding GO:0006605//protein targeting;GO:0019538//protein metabolic process gi|33468943|ref|NP_035720.1|/2.88665e-63/mitochondrial import inner membrane translocase subunit Tim17-A [Mus musculus] 67958 7736 3.246666667 3.36 0.049501961 Up 0.122560081 U2surp U2 snRNP-associated SURP domain containing K12842|1|0.0|1443|umr:103681545|U2-associated protein SR140 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding GO:0010467//gene expression;GO:0010467//gene expression gi|171460908|ref|NP_080752.2|/0/U2 snRNP-associated SURP motif-containing protein isoform 2 [Mus musculus] 70425 4394 3.36 3.246666667 -0.049501961 Down 0.122560081 Csnk1g3 "casein kinase 1, gamma 3" "K08958|1|0.0|809|mmu:70425|casein kinase 1, gamma [EC:2.7.11.1]" GO:0044424 GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0033218//amide binding GO:0006468//protein phosphorylation;GO:0007166//cell surface receptor signaling pathway gi|113462019|ref|NP_690022.2|/0/casein kinase I isoform gamma-3 [Mus musculus] 56454 3521 2.95 3.063333333 0.054387406 Up 0.122560081 Aldh18a1 "aldehyde dehydrogenase 18 family, member A1" K12657|1|0.0|1515|mmu:56454|delta-1-pyrroline-5-carboxylate synthetase [EC:2.7.2.11 1.2.1.41] GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane "GO:0032550;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016774//phosphotransferase activity, carboxyl group as acceptor;GO:0032550;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016774//phosphotransferase activity, carboxyl group as acceptor" GO:0006591//ornithine metabolic process;GO:0006560//proline metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0000052//citrulline metabolic process;GO:0006591//ornithine metabolic process;GO:0006560//proline metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0000052//citrulline metabolic process "gi|148709892|gb|EDL41838.1|/0/aldehyde dehydrogenase 18 family, member A1, isoform CRA_b, partial [Mus musculus]" 71175 10393.85 2.936666667 3.043333333 0.051472841 Up 0.122560081 Nipbl Nipped-B homolog (Drosophila) K06672|1|0.0|4694|mmu:71175|cohesin loading factor subunit SCC2 - - - - 53322 1703 3.55 3.663333333 0.045337956 Up 0.122560081 Nucb2 nucleobindin 2 K20371|1|0.0|772|mmu:53322|nucleobindin GO:0031965//nuclear membrane;GO:0031985//Golgi cisterna GO:0046872//metal ion binding;GO:0032813//tumor necrosis factor receptor superfamily binding GO:0006875//cellular metal ion homeostasis gi|194440700|ref|NP_001123951.1|/0/nucleobindin-2 precursor [Mus musculus] 75880 1006 3.046666667 3.16 0.052692894 Up 0.122560081 4930592A05Rik RIKEN cDNA 4930592A05 gene K01302|1|5e-15|84.3|mmu:54381|carboxypeptidase Q [EC:3.4.17.-] - - - - 233405 2595 3.266666667 3.376666667 0.04778052 Up 0.122560081 Vps33b vacuolar protein sorting 33B K20182|1|0.0|1194|pps:100974373|vacuolar protein sorting-associated protein 33;K16732|5|2e-150|536|apla:101789962|protein regulator of cytokinesis 1 GO:0005764//lysosome;GO:0030141//secretory granule;GO:0005774//vacuolar membrane;GO:0005770//late endosome GO:0019905//syntaxin binding GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0051875//pigment granule localization;GO:0033363//secretory granule organization gi|158937308|ref|NP_835171.2|/0/vacuolar protein sorting-associated protein 33B [Mus musculus] 20677 2969 3.4 3.51 0.045936284 Up 0.122560081 Sox4 SRY (sex determining region Y)-box 4 K09268|1|3e-136|488|mmu:20677|transcription factor SOX4/11/12 (SOX group C) GO:0043231//intracellular membrane-bounded organelle "GO:0001104//RNA polymerase II transcription cofactor activity;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000976//transcription regulatory region sequence-specific DNA binding" GO:0031016//pancreas development;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030098//lymphocyte differentiation;GO:0001678//cellular glucose homeostasis;GO:0003207//cardiac chamber formation;GO:0001822//kidney development;GO:0002320//lymphoid progenitor cell differentiation;GO:0003174//mitral valve development;GO:0010001//glial cell differentiation;GO:0030182//neuron differentiation;GO:0003281//ventricular septum development;GO:0008219//cell death;GO:0001838//embryonic epithelial tube formation;GO:0003284//septum primum development;GO:0021515//cell differentiation in spinal cord;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0048483//autonomic nervous system development;GO:0044267//cellular protein metabolic process;GO:0050796//regulation of insulin secretion;GO:0006950//response to stress;GO:0019827//stem cell population maintenance;GO:0031647//regulation of protein stability;GO:0003208//cardiac ventricle morphogenesis gi|56118239|ref|NP_033264.2|/2.82167e-135/transcription factor SOX-4 [Mus musculus] 104681 4160 3.306666667 3.196666667 -0.048809305 Down 0.122560081 Slc16a6 "solute carrier family 16 (monocarboxylic acid transporters), member 6" "K08183|1|0.0|959|mmu:104681|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 6" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763 gi|71067107|ref|NP_001025013.1|/0/monocarboxylate transporter 7 isoform a [Mus musculus] 17701 1931 2.976666667 2.866666667 -0.054323516 Down 0.122560081 Msx1 msh homeobox 1 K09341|1|7e-113|410|mmu:17701|homeobox protein MSX GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle "GO:0005515//protein binding;GO:0003677//DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding" GO:0030326//embryonic limb morphogenesis;GO:0003272//endocardial cushion formation;GO:0001501//skeletal system development;GO:0043009//chordate embryonic development;GO:0043392//negative regulation of DNA binding;GO:0033365//protein localization to organelle;GO:0016049//cell growth;GO:0042471//ear morphogenesis;GO:0042476//odontogenesis;GO:0000904//cell morphogenesis involved in differentiation;GO:0021536//diencephalon development;GO:0030509//BMP signaling pathway;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0051146//striated muscle cell differentiation;GO:0008283//cell proliferation;GO:0003002//regionalization;GO:0035094//response to nicotine;GO:0030879//mammary gland development;GO:0031647//regulation of protein stability;GO:0035878//nail development gi|9247217|gb|AAB31962.2|/7.83882e-132/homeobox protein [Mus sp.] 14070 2490 3.266666667 3.38 0.049203998 Up 0.122560081 F8a factor 8-associated gene A K20135|1|8e-133|477|mmu:14070|factor VIII intron 22 protein GO:0043231//intracellular membrane-bounded organelle - - gi|26328899|dbj|BAC28188.1|/1.0251e-140/unnamed protein product [Mus musculus] 21912 1791 122.21 120.79 -0.016861319 Down 0.122550679 Tspan7 tetraspanin 7 K06571|1|2e-143|511|mmu:21912|tetraspanin-7 - - - - 22781 3580 0.286666667 0.243333333 -0.236440196 Down 0.122522472 Ikzf4 IKAROS family zinc finger 4 K09220|1|0.0|1164|mmu:22781|IKAROS family zinc finger protein - - - gi|122114637|ref|NP_035902.2|/0/zinc finger protein Eos [Mus musculus] 100310809 2002 0.24 0.203333333 -0.239187664 Down 0.122522472 Gm10509 zinc finger protein 51 pseudogene K09228|1|0.0|1147|rno:499056|KRAB domain-containing zinc finger protein - - - gi|564296535|ref|XP_006223010.1|/0/PREDICTED: zinc finger protein 420-like isoform X1 [Rattus norvegicus] 14343 2492.57 0.24 0.203333333 -0.239187664 Down 0.122522472 Fut1 fucosyltransferase 1 K00718|1|0.0|710|rno:81919|galactoside 2-L-fucosyltransferase 1/2 [EC:2.4.1.69] GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane "GO:0031127//alpha-(1,2)-fucosyltransferase activity;GO:0031127//alpha-(1,2)-fucosyltransferase activity" GO:0070085//glycosylation;GO:0070085//glycosylation gi|49355810|ref|NP_032077.2|/0/galactoside 2-alpha-L-fucosyltransferase 1 isoform 1 [Mus musculus] 69804 868 90.29333333 91.69666667 0.022249818 Up 0.122522472 Tmem147 transmembrane protein 147 K06129|1|3e-17|91.3|tsp:Tsp_08042|lysophospholipase III [EC:3.1.1.5] GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle - - "gi|148692044|gb|EDL23991.1|/3.04213e-136/transmembrane protein 147, isoform CRA_a, partial [Mus musculus]" 67414 4531 81.63 80.23 -0.02495766 Down 0.122522472 Mfn1 mitofusin 1 K06030|1|0.0|1370|mmu:67414|mitofusin [EC:3.6.5.-] GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0009154//purine ribonucleotide catabolic process;GO:0032502//developmental process gi|60360220|dbj|BAD90354.1|/0/mKIAA4032 protein [Mus musculus] 30057 527 85.88 84.49333333 -0.023484676 Down 0.122503667 Timm8b translocase of inner mitochondrial membrane 8B K17780|1|9e-44|177|cfr:102521927|mitochondrial import inner membrane translocase subunit TIM8 GO:0019866//organelle inner membrane;GO:0005758//mitochondrial intermembrane space GO:0046914//transition metal ion binding GO:0050954//sensory perception of mechanical stimulus;GO:0006605//protein targeting;GO:0019538//protein metabolic process gi|743745169|ref|XP_010967219.1|/5.7748e-43/PREDICTED: mitochondrial import inner membrane translocase subunit Tim8 B [Camelus bactrianus] 76133 1088 0.413333333 0.463333333 0.164744762 Up 0.122456655 6230400D17Rik RIKEN cDNA 6230400D17 gene - - - - - 170459 2985 0.443333333 0.496666667 0.163886085 Up 0.122456655 Stard4 StAR-related lipid transfer (START) domain containing 4 "K16931|1|9e-09|65.5|cmy:102929435|steroidogenic acute regulatory protein, mitochondrial" - GO:0005488//binding GO:0051234//establishment of localization;GO:0010876//lipid localization gi|19526998|ref|NP_598535.1|/1.1551e-128/stAR-related lipid transfer protein 4 [Mus musculus] 100504195 2397 0.51 0.456666667 -0.15935576 Down 0.122456655 Micalcl MICAL C-terminal like K19947|1|3e-174|614|ecb:100055978|protein-methionine sulfoxide oxidase MICAL [EC:1.14.13.-] GO:0044424 GO:0019901//protein kinase binding GO:0048232//male gamete generation;GO:0048869//cellular developmental process "gi|148685083|gb|EDL17030.1|/0/mCG13320, isoform CRA_b [Mus musculus]" 108800 9896 0.5 0.446666667 -0.1627295 Down 0.122456655 Ston2 stonin 2 K20067|1|0.0|1713|mmu:108800|stonin-1/2 GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex - GO:0007267//cell-cell signaling;GO:0006897//endocytosis;GO:0015031//protein transport "gi|148687000|gb|EDL18947.1|/0/stonin 2, isoform CRA_a, partial [Mus musculus]" 100019 17959 0.446666667 0.4 -0.159198595 Down 0.122456655 Mdn1 midasin AAA ATPase 1 K14572|1|0.0|1.043e+04|mmu:100019|midasin GO:0031981//nuclear lumen GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding GO:0009154//purine ribonucleotide catabolic process;GO:0065003 gi|124487133|ref|NP_001074861.1|/0/midasin [Mus musculus] 22255 2109 0.043333333 0.07 0.691877705 Up 0.122447253 Uncx UNC homeobox K09328|1|0.0|666|mmu:22255|homeobox protein Unc-4 - - GO:0021772//olfactory bulb development;GO:0021510//spinal cord development;GO:0030154//cell differentiation;GO:0010467//gene expression;GO:0008283//cell proliferation gi|7305613|ref|NP_038730.1|/0/homeobox protein unc-4 homolog [Mus musculus] 23970 3708.58 77.41666667 78.76 0.02481892 Up 0.122447253 Pacsin2 protein kinase C and casein kinase substrate in neurons 2 K20123|1|0.0|896|mmu:23970|protein kinase C and casein kinase substrate in neurons protein GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006796//phosphate-containing compound metabolic process;GO:0007154//cell communication;GO:0006897//endocytosis;GO:0006796//phosphate-containing compound metabolic process;GO:0007154//cell communication;GO:0006897//endocytosis;GO:0006796//phosphate-containing compound metabolic process;GO:0007154//cell communication;GO:0006897//endocytosis gi|7106381|ref|NP_035992.1|/0/protein kinase C and casein kinase substrate in neurons protein 2 [Mus musculus] 13349 1158 0.05 0.08 0.678071905 Up 0.122447253 Ackr1 atypical chemokine receptor 1 (Duffy blood group) K06574|1|7e-173|608|mmu:13349|Duffy blood group glycoprotein GO:0031224//intrinsic component of membrane GO:0019956//chemokine binding;GO:0004888//transmembrane signaling receptor activity GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway;GO:0001817//regulation of cytokine production gi|130502090|ref|NP_034175.2|/5.52835e-172/atypical chemokine receptor 1 [Mus musculus] 14685 2222 0.05 0.08 0.678071905 Up 0.122447253 Gnat1 "guanine nucleotide binding protein, alpha transducing 1" K04631|1|0.0|670|pale:102898169|guanine nucleotide-binding protein G(t) subunit alpha 1/2 - - - gi|742171392|ref|XP_010850131.1|/0/PREDICTED: guanine nucleotide-binding protein G(t) subunit alpha-1 isoform X1 [Bison bison bison] 234542 1923 0.076666667 0.046666667 -0.716207034 Down 0.122447253 Rtbdn retbindin K13649|1|2e-10|70.1|mgp:100547944|folate receptor - - - gi|21450337|ref|NP_659178.1|/4.53439e-141/retbindin precursor [Mus musculus] 241263 7143 0.08 0.05 -0.678071905 Down 0.122447253 Gpr158 G protein-coupled receptor 158 K08469|1|0.0|2289|mmu:241263|G protein-coupled receptor 158 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0007009//plasma membrane organization gi|52350563|ref|NP_001004761.1|/0/probable G-protein coupled receptor 158 precursor [Mus musculus] 57014 2411 0.07 0.043333333 -0.691877705 Down 0.122447253 Htr3b 5-hydroxytryptamine (serotonin) receptor 3B K04819|1|0.0|852|mmu:57014|5-hydroxytryptamine receptor 3 GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0044297//cell body;GO:0097060//synaptic membrane GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0008227//G-protein coupled amine receptor activity GO:0070848//response to growth factor;GO:0006811//ion transport;GO:0007186//G-protein coupled receptor signaling pathway gi|9938026|ref|NP_064670.1|/0/5-hydroxytryptamine receptor 3B precursor [Mus musculus] 107766 1252 0.046666667 0.076666667 0.716207034 Up 0.122447253 Haao "3-hydroxyanthranilate 3,4-dioxygenase" "K00452|1|6e-168|592|mmu:107766|3-hydroxyanthranilate 3,4-dioxygenase [EC:1.13.11.6]" GO:0005740//mitochondrial envelope "GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0005506//iron ion binding" GO:0010038//response to metal ion;GO:0043648//dicarboxylic acid metabolic process;GO:0019725//cellular homeostasis;GO:0019359//nicotinamide nucleotide biosynthetic process "gi|17921976|ref|NP_079601.1|/4.57884e-167/3-hydroxyanthranilate 3,4-dioxygenase [Mus musculus]" 328837 2350 0.05 0.08 0.678071905 Up 0.122447253 C330011F03Rik RIKEN cDNA C330011F03 gene - - - - gi|148691703|gb|EDL23650.1|/4.27594e-59/mCG147801 [Mus musculus] 329387 2674 0.086666667 0.053333333 -0.700439718 Down 0.122447253 C230014O12Rik RIKEN cDNA C230014O12 gene - - - - - 239410 3350 0.05 0.08 0.678071905 Up 0.122447253 A930017M01Rik "Smg-5 homolog, nonsense mediated mRNA decay factor pseudogene" K11125|1|0.0|1473|ngi:103748743|protein SMG5 - - - "gi|148676785|gb|EDL08732.1|/0/RIKEN cDNA A930017M01, isoform CRA_a [Mus musculus]" 18155 2101 0.046666667 0.076666667 0.716207034 Up 0.122447253 Pnoc prepronociceptin K18832|1|8e-07|58.5|xma:102232977|proenkephalin A - - GO:0007186//G-protein coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007267//cell-cell signaling "gi|148704076|gb|EDL36023.1|/7.41894e-87/prepronociceptin, isoform CRA_a, partial [Mus musculus]" 68790 2714 0.046666667 0.076666667 0.716207034 Up 0.122447253 Fendrr Foxf1 adjacent non-coding developmental regulatory RNA - - - - - 75858 1083 0.053333333 0.086666667 0.700439718 Up 0.122447253 Speer4cos "spermatogenesis associated glutamate (E)-rich protein 4C, opposite strand transcript" - - - - - 14183 5223 0.05 0.08 0.678071905 Up 0.122447253 Fgfr2 fibroblast growth factor receptor 2 K05093|1|0.0|1374|cfa:415125|fibroblast growth factor receptor 2 [EC:2.7.10.1] GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0044444//cytoplasmic part;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0044444//cytoplasmic part;GO:0016021//integral component of membrane GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0042802//identical protein binding;GO:0019838//growth factor binding;GO:0005539//glycosaminoglycan binding;GO:0032550;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0042802//identical protein binding;GO:0019838//growth factor binding;GO:0005539//glycosaminoglycan binding;GO:0032550 GO:0007067//mitotic nuclear division;GO:0035264//multicellular organism growth;GO:0060442//branching involved in prostate gland morphogenesis;GO:0001942//hair follicle development;GO:0051145//smooth muscle cell differentiation;GO:0060445//branching involved in salivary gland morphogenesis;GO:0002067//glandular epithelial cell differentiation;GO:0021761//limbic system development;GO:0051726//regulation of cell cycle;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0003208//cardiac ventricle morphogenesis;GO:0033687//osteoblast proliferation;GO:0012501//programmed cell death;GO:0060363//cranial suture morphogenesis;GO:0006468//protein phosphorylation;GO:0007224//smoothened signaling pathway;GO:0010463//mesenchymal cell proliferation;GO:0048546//digestive tract morphogenesis;GO:0042471//ear morphogenesis;GO:0001649//osteoblast differentiation;GO:0048741//skeletal muscle fiber development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0021869//forebrain ventricular zone progenitor cell division;GO:0048704//embryonic skeletal system morphogenesis;GO:0045165//cell fate commitment;GO:0003151//outflow tract morphogenesis;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0030177//positive regulation of Wnt signaling pathway;GO:0016192//vesicle-mediated transport;GO:0043410//positive regulation of MAPK cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0010517//regulation of phospholipase activity;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0021859//pyramidal neuron differentiation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0007067//mitotic nuclear division;GO:0035264//multicellular organism growth;GO:0060442//branching involved in prostate gland morphogenesis;GO:0001942//hair follicle development;GO:0051145//smooth muscle cell differentiation;GO:0060445//branching involved in salivary gland morphogenesis;GO:0002067//glandular epithelial cell differentiation;GO:0021761//limbic system development;GO:0051726//regulation of cell cycle;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0003208//cardiac ventricle morphogenesis;GO:0033687//osteoblast proliferation;GO:0012501//programmed cell death;GO:0060363//cranial suture morphogenesis;GO:0006468//protein phosphorylation;GO:0007224//smoothened signaling pathway;GO:0010463//mesenchymal cell proliferation;GO:0048546//digestive tract morphogenesis;GO:0042471//ear morphogenesis;GO:0001649//osteoblast differentiation;GO:0048741//skeletal muscle fiber development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0021869//forebrain ventricular zone progenitor cell division;GO:0048704//embryonic skeletal system morphogenesis;GO:0045165//cell fate commitment;GO:0003151//outflow tract morphogenesis;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0030177//positive regulation of Wnt signaling pathway;GO:0016192//vesicle-mediated transport;GO:0043410//positive regulation of MAPK cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0010517//regulation of phospholipase activity;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0021859//pyramidal neuron differentiation;GO:0050679//positive regulation of epithelial cell proliferation gi|116089355|ref|NP_963895.2|/0/fibroblast growth factor receptor 2 isoform IIIb [Mus musculus] 15978 1210 0.046666667 0.076666667 0.716207034 Up 0.122447253 Ifng interferon gamma K04687|1|2e-76|288|mmu:15978|interferon gamma - - - - 15394 2271 0.046666667 0.076666667 0.716207034 Up 0.122447253 Hoxa1 homeobox A1 K09301|1|3e-157|558|pps:100980226|homeobox protein HoxA/B/D1 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0007411//axon guidance;GO:0021598;GO:0006366//transcription from RNA polymerase II promoter;GO:0007632//visual behavior;GO:0021546//rhombomere development;GO:0021548//pons development;GO:0003002//regionalization;GO:0050954//sensory perception of mechanical stimulus;GO:0021604;GO:0042471//ear morphogenesis;GO:0048514//blood vessel morphogenesis;GO:0048646//anatomical structure formation involved in morphogenesis "gi|742184669|ref|XP_010853715.1|/7.039e-71/PREDICTED: homeobox protein Hox-A1, partial [Bison bison bison]" 19252 1952 81.68 82.95 0.022259115 Up 0.122372034 Dusp1 dual specificity phosphatase 1 K04459|1|0.0|731|mmu:19252|dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] - - - gi|7305423|ref|NP_038670.1|/0/dual specificity protein phosphatase 1 [Mus musculus] 17999 5494 76.35333333 77.54333333 0.022311611 Up 0.122183986 Nedd4 "neural precursor cell expressed, developmentally down-regulated 4" K10591|1|0.0|1770|mmu:17999|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] - - - gi|1374782|dbj|BAA12803.1|/0/Nedd4 [Mus musculus] 18583 6038.13 9.09 9.296666667 0.032433234 Up 0.122155779 Pde7a phosphodiesterase 7A "K18436|1|0.0|896|mcf:101926015|high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]" GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part "GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity" GO:0046058//cAMP metabolic process;GO:0007154//cell communication;GO:0046058//cAMP metabolic process;GO:0007154//cell communication "gi|170295857|ref|NP_001116231.1|/0/high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A isoform 2 [Mus musculus]" 66459 5410 11.77 11.97666667 0.025112114 Up 0.122155779 Pyurf Pigy upstream reading frame "K11001|1|5e-27|127|nle:100585255|phosphatidylinositol glycan anchor biosynthesis, class Y" GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0031090//organelle membrane - GO:0006497//protein lipidation "gi|148672796|gb|EDL04743.1|/7.10165e-42/phosphatidylinositol glycan anchor biosynthesis, class Y, isoform CRA_b, partial [Mus musculus]" 66671 1976 9.94 10.15 0.030161971 Up 0.122155779 Ccnh cyclin H K06634|1|4e-175|617|mmu:66671|cyclin H GO:0005667//transcription factor complex "GO:0004674//protein serine/threonine kinase activity;GO:0019887//protein kinase regulator activity;GO:0042623//ATPase activity, coupled;GO:0019900//kinase binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0044772//mitotic cell cycle phase transition;GO:0006397//mRNA processing;GO:0044764;GO:0051320;GO:0006796//phosphate-containing compound metabolic process;GO:0051318;GO:0006289//nucleotide-excision repair;GO:0051726//regulation of cell cycle;GO:0006464//cellular protein modification process;GO:0006360//transcription from RNA polymerase I promoter gi|12963599|ref|NP_075732.1|/3.22522e-174/cyclin-H [Mus musculus] 68015 2297 77.74 78.90333333 0.021429142 Up 0.122108767 Trap1 TNF receptor-associated protein 1 K09488|1|0.0|1381|mmu:68015|TNF receptor-associated protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0032550 GO:0006979//response to oxidative stress;GO:0044267//cellular protein metabolic process "gi|148664808|gb|EDK97224.1|/0/TNF receptor-associated protein 1, partial [Mus musculus]" 26893 1094 95.60666667 94.44666667 -0.017611341 Down 0.122108767 Cops6 COP9 signalosome subunit 6 K12179|1|5e-164|579|mmu:26893|COP9 signalosome complex subunit 6 - - - - 215476 10546 0.726666667 0.783333333 0.108332622 Up 0.122061755 Prr14l proline rich 14-like - - - - gi|258679492|ref|NP_919321.2|/0/protein PRR14L [Mus musculus] 208194 3870 0.846666667 0.783333333 -0.11216774 Down 0.122061755 Exog "endo/exonuclease (5'-3'), endonuclease G-like" "K15050|1|0.0|676|mmu:208194|nuclease EXOG, mitochondrial" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0004518//nuclease activity;GO:0097159//organic cyclic compound binding;GO:0043169//cation binding;GO:0004518//nuclease activity;GO:0097159//organic cyclic compound binding - "gi|287327708|ref|NP_001165607.1|/0/nuclease EXOG, mitochondrial isoform 1 precursor [Mus musculus]" 209131 7507 0.823333333 0.886666667 0.106915204 Up 0.122061755 Snx30 sorting nexin family member 30 K17921|1|0.0|813|mmu:209131|sorting nexin-7/30 - - - - 77994 3151 0.83 0.77 -0.108252891 Down 0.122061755 Mir99ahg Mir99a and Mirlet7c-1 host gene (non-protein coding) - - - - - 19683 3208 0.053333333 0.08 0.584962501 Up 0.122052352 Rdh16 retinol dehydrogenase 16 K11154|1|0.0|640|mmu:19683|retinol dehydrogenase 16 [EC:1.1.1.-] GO:0044432;GO:0016021//integral component of membrane "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0036094//small molecule binding" GO:0002138//retinoic acid biosynthetic process gi|6677697|ref|NP_033066.1|/0/retinol dehydrogenase 16 [Mus musculus] 384214 1262 0.046666667 0.073333333 0.652076697 Up 0.122052352 Ephx4 epoxide hydrolase 4 "K08059|1|2e-49|199|bfo:BRAFLDRAFT_126371|interferon, gamma-inducible protein 30;K08726|2|4e-38|161|rro:104673945|soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]" - - - "gi|148688219|gb|EDL20166.1|/0/abhydrolase domain containing 7, partial [Mus musculus]" 229672 1993 0.1 0.066666667 -0.584962501 Down 0.122052352 Bcl2l15 BCLl2-like 15 - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - - gi|219281865|ref|NP_001136432.1|/2.31826e-87/bcl-2-like protein 15 isoform 2 [Mus musculus] 65254 5077 0.086666667 0.056666667 -0.612976877 Down 0.122052352 Dpysl5 dihydropyrimidinase-like 5 K07529|1|0.0|1143|mmu:65254|dihydropyrimidinase-like 5 GO:0032991//macromolecular complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044424 "GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds" GO:0006935//chemotaxis;GO:0006206//pyrimidine nucleobase metabolic process;GO:0030154//cell differentiation "gi|148705344|gb|EDL37291.1|/0/dihydropyrimidinase-like 5, isoform CRA_c, partial [Mus musculus]" 241612 5104 0.05 0.076666667 0.61667136 Up 0.122052352 Slc5a12 "solute carrier family 5 (sodium/glucose cotransporter), member 12" "K14388|1|0.0|1167|mmu:241612|solute carrier family 5 (sodium-coupled monocarboxylate transporter), member 8/12" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0030001//metal ion transport;GO:0044763;GO:0030001//metal ion transport;GO:0044763 gi|51491856|ref|NP_001003915.1|/0/sodium-coupled monocarboxylate transporter 2 isoform 1 [Mus musculus] 11831 2060 0.056666667 0.09 0.667424661 Up 0.122052352 Aqp6 aquaporin 6 K09868|1|2e-150|535|mmu:11831|aquaporin-6 GO:0016021//integral component of membrane;GO:0030133//transport vesicle GO:0015103//inorganic anion transmembrane transporter activity;GO:0005372//water transmembrane transporter activity;GO:0022829//wide pore channel activity;GO:0005216//ion channel activity GO:0044763;GO:0009887//organ morphogenesis;GO:0015698//inorganic anion transport;GO:0042044//fluid transport gi|28201966|ref|NP_780296.1|/1.7005e-149/aquaporin-6 [Mus musculus] 320975 1710 0.09 0.06 -0.584962501 Down 0.122052352 D330050G23Rik RIKEN cDNA D330050G23 gene - - - - "gi|148695944|gb|EDL27891.1|/4.59706e-33/mCG144765, partial [Mus musculus]" 626693 1546 0.066666667 0.1 0.584962501 Up 0.122052352 Gm15713 predicted gene 15713 - - - - - 238257 3282 0.056666667 0.086666667 0.612976877 Up 0.122052352 Tmem30b transmembrane protein 30B - - - - - 83453 4190 0.086666667 0.056666667 -0.612976877 Down 0.122052352 Chrdl1 chordin-like 1 K17280|1|3e-86|323|phi:102111340|chordin-like protein 2 - - GO:0001654//eye development;GO:0045165//cell fate commitment;GO:0001654//eye development;GO:0045165//cell fate commitment gi|625243530|ref|XP_007613006.1|/0/PREDICTED: chordin-like protein 1 isoform X8 [Cricetulus griseus] 73671 2060 0.073333333 0.046666667 -0.652076697 Down 0.122052352 Sult6b1 "sulfotransferase family, cytosolic, 6B, member 1" K01025|1|5e-45|185|bfo:BRAFLDRAFT_238281| GO:0044424 "GO:0016782//transferase activity, transferring sulfur-containing groups" - gi|254692894|ref|NP_001157097.1|/3.63541e-176/sulfotransferase 6B1 [Mus musculus] 64385 2051.01 0.076666667 0.05 -0.61667136 Down 0.122052352 Cyp4f14 "cytochrome P450, family 4, subfamily f, polypeptide 14" K17726|1|0.0|1048|mmu:64385|leukotriene-B4 20-monooxygenase / phylloquinone omega-hydroxylase [EC:1.14.13.30 1.14.13.194] GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0050542;GO:0046906//tetrapyrrole binding;GO:0052870//tocopherol omega-hydroxylase activity;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0050542;GO:0046906//tetrapyrrole binding;GO:0052870//tocopherol omega-hydroxylase activity;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0050542;GO:0046906//tetrapyrrole binding;GO:0052870//tocopherol omega-hydroxylase activity;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0050542;GO:0046906//tetrapyrrole binding;GO:0052870//tocopherol omega-hydroxylase activity;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0050542;GO:0046906//tetrapyrrole binding;GO:0052870//tocopherol omega-hydroxylase activity;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0042221//response to chemical;GO:0001676//long-chain fatty acid metabolic process;GO:0042221//response to chemical;GO:0001676//long-chain fatty acid metabolic process;GO:0042221//response to chemical;GO:0001676//long-chain fatty acid metabolic process;GO:0042221//response to chemical;GO:0001676//long-chain fatty acid metabolic process;GO:0042221//response to chemical;GO:0001676//long-chain fatty acid metabolic process gi|569001333|ref|XP_006524844.1|/0/PREDICTED: leukotriene-B4 omega-hydroxylase 3 isoform X2 [Mus musculus] 235048 3597 0.096666667 0.063333333 -0.610053482 Down 0.122052352 Zfp599 zinc finger protein 599 K09228|1|0.0|1173|mmu:235048|KRAB domain-containing zinc finger protein - - - "gi|148693320|gb|EDL25267.1|/0/cDNA sequence BC050092, isoform CRA_a, partial [Mus musculus]" 22599 3287 0.09 0.06 -0.584962501 Down 0.122052352 Slc6a20b "solute carrier family 6 (neurotransmitter transporter), member 20B" "K05048|1|0.0|1254|mmu:22599|solute carrier family 6 (neurotransmitter transporter, amino acid/orphan) member 15/16/17/18/20" GO:0044459;GO:0016021//integral component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0046943//carboxylic acid transmembrane transporter activity GO:0006865//amino acid transport;GO:0006812//cation transport gi|31981421|ref|NP_035861.2|/0/sodium- and chloride-dependent transporter XTRP3B [Mus musculus] 74062 1121 0.053333333 0.08 0.584962501 Up 0.122052352 Speer8-ps1 "spermatogenesis associated glutamate (E)-rich protein 8, pseudogene 1" - - - - - 235628 1595 0.083333333 0.053333333 -0.64385619 Down 0.122052352 Prss42 "protease, serine 42" K09629|1|5e-53|211|mmu:353130|serine protease 33 [EC:3.4.21.-];K09628|3|1e-52|209|gja:107119119|serine protease 27 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|23346527|ref|NP_694739.1|/0/serine protease 42 precursor [Mus musculus] 279499 3007 0.083333333 0.053333333 -0.64385619 Down 0.122052352 Kctd19 potassium channel tetramerisation domain containing 19 "K03849|1|9e-06|55.5|cmk:103177229|alpha-1,3-glucosyltransferase [EC:2.4.1.265]" - - GO:0051259//protein oligomerization;GO:0051259//protein oligomerization gi|29244318|ref|NP_808459.1|/0/BTB/POZ domain-containing protein KCTD19 isoform 1 [Mus musculus] 68680 912 101.7033333 100.61 -0.015593257 Down 0.121995938 Fitm1 fat storage-inducing transmembrane protein 1 K11801|1|2e-26|122|asn:102385236|WD repeat-containing protein 23 GO:0031227//intrinsic component of endoplasmic reticulum membrane - GO:0010884//positive regulation of lipid storage;GO:0006996//organelle organization "gi|23272977|gb|AAH37188.1|/1.58203e-138/1110028A07Rik protein, partial [Mus musculus]" 16480 5009 97.88333333 98.96666667 0.015879455 Up 0.121958329 Jup junction plakoglobin K10056|1|0.0|1363|mmu:16480|junction plakoglobin - - - gi|28395018|ref|NP_034723.1|/0/junction plakoglobin [Mus musculus] 12632 2940 74.76333333 73.69 -0.02086204 Down 0.121939524 Cfl2 "cofilin 2, muscle" K05765|1|4e-85|318|rno:366624|cofilin GO:0005856//cytoskeleton;GO:0034399//nuclear periphery GO:0008092//cytoskeletal protein binding GO:0008154//actin polymerization or depolymerization "gi|148704795|gb|EDL36742.1|/3.82084e-84/cofilin 2, muscle, isoform CRA_b, partial [Mus musculus]" 108030 5845 0.546666667 0.493333333 -0.148098639 Down 0.121930121 Lin7a lin-7 homolog A (C. elegans) K19931|1|2e-75|252|cmk:103185342|protein lin-7 GO:0043296//apical junction complex;GO:0044459;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0044459;GO:0045202//synapse GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding GO:0016192//vesicle-mediated transport;GO:0045184//establishment of protein localization;GO:0001505//regulation of neurotransmitter levels;GO:0043583//ear development;GO:0065003;GO:0016192//vesicle-mediated transport;GO:0001505//regulation of neurotransmitter levels;GO:0043583//ear development;GO:0065003 gi|632971039|ref|XP_007901976.1|/1.61696e-74/PREDICTED: protein lin-7 homolog A isoform X1 [Callorhinchus milii] 218973 4190 0.21 0.246666667 0.232173442 Up 0.121930121 Wdhd1 WD repeat and HMG-box DNA binding protein 1 K11274|1|0.0|2094|mmu:218973|chromosome transmission fidelity protein 4 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0019899//enzyme binding GO:0070827//chromatin maintenance;GO:0010467//gene expression gi|40254224|ref|NP_766186.2|/0/WD repeat and HMG-box DNA-binding protein 1 [Mus musculus] 74413 5665 0.21 0.246666667 0.232173442 Up 0.121930121 Tc2n "tandem C2 domains, nuclear" K17287|1|0.0|851|mmu:74413|tandem C2 domains nuclear protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|21312724|ref|NP_083200.1|/0/tandem C2 domains nuclear protein [Mus musculus] 18612 2334 0.27 0.23 -0.231325546 Down 0.121930121 Etv4 ets variant 4 K15592|1|0.0|995|mmu:18612|ets translocation variant 4 - - - - 216859 2482 0.276666667 0.236666667 -0.225292312 Down 0.121930121 Acap1 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 1" "K12489|1|0.0|1280|mmu:216859|Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein" - GO:0046914//transition metal ion binding;GO:0060089;GO:0008289//lipid binding;GO:0003824//catalytic activity GO:0006629//lipid metabolic process;GO:0045184//establishment of protein localization;GO:0032012//regulation of ARF protein signal transduction "gi|27881415|ref|NP_722483.2|/0/arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 [Mus musculus]" 70422 5922 0.503333333 0.453333333 -0.150941898 Down 0.121930121 Ints2 integrator complex subunit 2 K13139|1|0.0|2277|mmu:70422|integrator complex subunit 2 "GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0031224//intrinsic component of membrane" - GO:0016073//snRNA metabolic process "gi|148683836|gb|EDL15783.1|/0/integrator complex subunit 2, isoform CRA_b, partial [Mus musculus]" 75259 2086.9 0.48 0.533333333 0.152003093 Up 0.121930121 4930556M19Rik RIKEN cDNA 4930556M19 gene - - - - - 667214 3863 0.296666667 0.253333333 -0.227805918 Down 0.121930121 9930111J21Rik1 RIKEN cDNA 9930111J21 gene 1 K17072|1|0.0|1059|mmu:432555|interferon gamma inducible protein 47 - GO:0016787//hydrolase activity GO:0006950//response to stress gi|167931392|ref|NP_001108151.1|/0/interferon-inducible GTPase family member [Mus musculus] 11484 1537 0.45 0.5 0.152003093 Up 0.121930121 Aspa aspartoacylase K01437|1|2e-175|618|mmu:11484|aspartoacylase [EC:3.5.1.15] GO:0043231//intracellular membrane-bounded organelle "GO:0043169//cation binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0045687//positive regulation of glial cell differentiation;GO:0032787//monocarboxylic acid metabolic process;GO:0014003//oligodendrocyte development gi|31560279|ref|NP_075602.2|/1.36329e-174/aspartoacylase [Mus musculus] 208164 1528 0.256666667 0.3 0.225066556 Up 0.121930121 Fam180a "family with sequence similarity 180, member A" - - - - gi|27734066|ref|NP_775551.1|/1.064e-70/protein FAM180A precursor [Mus musculus] 75729 5187 0.466666667 0.42 -0.152003093 Down 0.121930121 Fam227a "family with sequence similarity 227, member A" - - - - gi|256000814|ref|NP_083683.1|/0/protein FAM227A [Mus musculus] 93739 996 72.08333333 73.12 0.020600343 Up 0.121836098 Gabarapl2 gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2 K08341|1|1e-62|242|acs:100558896|GABA(A) receptor-associated protein GO:0005774//vacuolar membrane;GO:0031982//vesicle;GO:0012505//endomembrane system GO:0019899//enzyme binding;GO:0005102//receptor binding;GO:0015631//tubulin binding GO:0043462//regulation of ATPase activity;GO:0045184//establishment of protein localization;GO:0009895;GO:0048193//Golgi vesicle transport gi|637353612|ref|XP_003227447.2|/1.0673e-61/PREDICTED: gamma-aminobutyric acid receptor-associated protein-like 2 [Anolis carolinensis] 74011 2687 1.533333333 1.61 0.070389328 Up 0.121732671 Slc25a27 "solute carrier family 25, member 27" "K15112|1|0.0|652|mmu:74011|solute carrier family 25 (mitochondrial uncoupling protein), member 27" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0019866//organelle inner membrane - GO:0051560//mitochondrial calcium ion homeostasis;GO:0006915//apoptotic process;GO:0045837//negative regulation of membrane potential;GO:0043583//ear development;GO:0008283//cell proliferation;GO:0010827//regulation of glucose transport;GO:0044237//cellular metabolic process gi|21312006|ref|NP_082987.1|/0/mitochondrial uncoupling protein 4 [Mus musculus] 68729 5637 1.793333333 1.876666667 0.06552875 Up 0.121732671 Trim37 tripartite motif-containing 37 K10608|1|0.0|1699|mmu:68729|tripartite motif-containing protein 37 [EC:2.3.2.27] - - - - 320301 3304 1.483333333 1.56 0.072703194 Up 0.121732671 E530011L22Rik RIKEN cDNA E530011L22 gene - - - - gi|149018180|gb|EDL76821.1|/2.29056e-08/rCG62930 [Rattus norvegicus] 12416 3770 1.77 1.69 -0.066726114 Down 0.121732671 Cbx2 chromobox 2 K11451|1|0.0|822|mmu:12416|chromobox protein 2 - - - - 69806 2721 1.556666667 1.633333333 0.069359199 Up 0.121732671 Slc39a11 "solute carrier family 39 (metal ion transporter), member 11" "K14717|1|3e-153|545|mmu:69806|solute carrier family 39 (zinc transporter), member 11" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0008324//cation transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity GO:0000041//transition metal ion transport;GO:0044763;GO:0000041//transition metal ion transport;GO:0044763 gi|262073041|ref|NP_081492.4|/1.87201e-154/zinc transporter ZIP11 isoform 2 [Mus musculus] 102466970 123 1.646666667 1.563333333 -0.074923119 Down 0.121732671 Mir1957b microRNA 1957b - - - - - 75302 8902 1.676666667 1.76 0.06997953 Up 0.121732671 Asxl2 additional sex combs like 2 (Drosophila) K11471|1|0.0|2324|mmu:75302|additional sex combs-like protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0005102//receptor binding;GO:0043169//cation binding;GO:0005102//receptor binding GO:0009967//positive regulation of signal transduction;GO:0006366//transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0009967//positive regulation of signal transduction;GO:0006366//transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation gi|153792093|ref|NP_766009.2|/0/putative Polycomb group protein ASXL2 isoform 2 [Mus musculus] 19335 4209 1.563333333 1.643333333 0.071999724 Up 0.121732671 Rab23 "RAB23, member RAS oncogene family" K06234|1|3e-130|469|mmu:19335|Ras-related protein Rab-23 GO:0016020//membrane;GO:0005773//vacuole;GO:0030139//endocytic vesicle;GO:0016020//membrane;GO:0005773//vacuole;GO:0030139//endocytic vesicle GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0048731//system development;GO:0030326//embryonic limb morphogenesis;GO:0042308//negative regulation of protein import into nucleus;GO:0007224//smoothened signaling pathway;GO:0009154//purine ribonucleotide catabolic process;GO:0006508//proteolysis;GO:0009953//dorsal/ventral pattern formation;GO:0006952//defense response;GO:0035556//intracellular signal transduction;GO:0048731//system development;GO:0030326//embryonic limb morphogenesis;GO:0042308//negative regulation of protein import into nucleus;GO:0007224//smoothened signaling pathway;GO:0009154//purine ribonucleotide catabolic process;GO:0006508//proteolysis;GO:0009953//dorsal/ventral pattern formation;GO:0006952//defense response;GO:0035556//intracellular signal transduction "gi|148682490|gb|EDL14437.1|/4.444e-145/RAB23, member RAS oncogene family, isoform CRA_b, partial [Mus musculus]" 381695 8998 1.723333333 1.806666667 0.068128571 Up 0.121732671 N4bp2l2 NEDD4 binding protein 2-like 2 K15720|1|1e-42|179|cmk:103175864|NEDD4-binding protein 2 [EC:3.-.-.-] GO:0043231//intracellular membrane-bounded organelle - GO:0001701//in utero embryonic development gi|158186629|ref|NP_958757.2|/0/NEDD4-binding protein 2-like 2 [Mus musculus] 76251 5589 1.53 1.453333333 -0.074166019 Down 0.121732671 Ercc6l2 "excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2" K20098|1|0.0|2672|rno:361197|DNA excision repair protein ERCC-6-like 2 [EC:3.6.4.-] - - - gi|169790814|ref|NP_001013626.2|/0/DNA excision repair protein ERCC-6-like 2 isoform 1 [Mus musculus] 380718 2365 1.686666667 1.61 -0.067114196 Down 0.121732671 Mks1 "Meckel syndrome, type 1" K19332|1|0.0|1069|mmu:380718|Meckel syndrome type 1 protein GO:0005815//microtubule organizing center;GO:0035869//ciliary transition zone - GO:0048858//cell projection morphogenesis;GO:0060562//epithelial tube morphogenesis;GO:0010927 gi|148747585|ref|NP_001034773.2|/0/Meckel syndrome type 1 protein homolog [Mus musculus] 17768 2070 1.573333333 1.496666667 -0.072071415 Down 0.121732671 Mthfd2 "methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase" "K13403|1|5e-179|630|mmu:17768|methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]" - - - "gi|6678952|ref|NP_032664.1|/3.91304e-178/bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial precursor [Mus musculus]" 102774 2542 1.566666667 1.646666667 0.071850285 Up 0.121732671 Bbs4 Bardet-Biedl syndrome 4 (human) K16531|1|0.0|912|mmu:102774|Bardet-Biedl syndrome 4 protein GO:0031090//organelle membrane;GO:0043234//protein complex;GO:0072372//primary cilium;GO:0005813//centrosome GO:0015631//tubulin binding;GO:0003774//motor activity GO:0014020;GO:0010467//gene expression;GO:0001894//tissue homeostasis;GO:0007601//visual perception;GO:0032099//negative regulation of appetite;GO:0042384//cilium assembly;GO:0021543//pallium development;GO:0031175//neuron projection development;GO:0072393//microtubule anchoring at microtubule organizing center;GO:0035264//multicellular organism growth;GO:0006629//lipid metabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0060295;GO:0007606//sensory perception of chemical stimulus;GO:0021544//subpallium development;GO:0003073//regulation of systemic arterial blood pressure;GO:0000910//cytokinesis;GO:0007281//germ cell development;GO:0042462//eye photoreceptor cell development;GO:0034504//protein localization to nucleus;GO:0031023//microtubule organizing center organization;GO:0009725//response to hormone "gi|59808034|gb|AAH89507.1|/0/Bbs4 protein, partial [Mus musculus]" 54403 7450.48 1.64 1.716666667 0.065914117 Up 0.121732671 Slc4a4 "solute carrier family 4 (anion exchanger), member 4" "K13575|1|0.0|2010|mmu:54403|solute carrier family 4 (sodium bicarbonate cotransporter), member 4" GO:0044459;GO:0016021//integral component of membrane;GO:0044459;GO:0016021//integral component of membrane;GO:0044459;GO:0016021//integral component of membrane GO:0015081//sodium ion transmembrane transporter activity;GO:0005488//binding;GO:0015301//anion:anion antiporter activity;GO:0015081//sodium ion transmembrane transporter activity;GO:0015081//sodium ion transmembrane transporter activity;GO:0005488//binding;GO:0015301//anion:anion antiporter activity GO:0055067;GO:0015711//organic anion transport;GO:0006814//sodium ion transport;GO:0055067;GO:0015711//organic anion transport;GO:0030001//metal ion transport;GO:0055067;GO:0015711//organic anion transport;GO:0006814//sodium ion transport gi|308210768|ref|NP_001184076.1|/0/electrogenic sodium bicarbonate cotransporter 1 isoform c [Mus musculus] 227525 3756.13 1.666666667 1.746666667 0.067638717 Up 0.121732671 Dclre1c DNA cross-link repair 1C K10887|1|0.0|780|mmu:227525|DNA cross-link repair 1C protein [EC:3.1.-.-] - - - - 216799 4021 0.28 0.24 -0.222392421 Down 0.121657452 Nlrp3 "NLR family, pyrin domain containing 3" "K12800|1|0.0|1960|mmu:216799|NACHT, LRR and PYD domains-containing protein 3" GO:0044424;GO:0043234//protein complex GO:0032550 GO:0032496//response to lipopolysaccharide;GO:0002526//acute inflammatory response;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0032731//positive regulation of interleukin-1 beta production;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0002252;GO:0032691//negative regulation of interleukin-1 beta production "gi|22003870|ref|NP_665826.1|/0/NACHT, LRR and PYD domains-containing protein 3 [Mus musculus]" 13124 1950 0.26 0.303333333 0.222392421 Up 0.121657452 Cyp8b1 "cytochrome P450, family 8, subfamily b, polypeptide 1" K07431|1|0.0|928|mmu:13124|sterol 12-alpha-hydroxylase [EC:1.14.18.8 1.14.13.96] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0008395//steroid hydroxylase activity" GO:0044710 gi|227497652|ref|NP_034142.3|/0/7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase [Mus musculus] 19363 1858 0.286666667 0.246666667 -0.216811389 Down 0.121657452 Rad51b RAD51 paralog B K10869|1|0.0|649|rno:500679|RAD51-like protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen "GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled" GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0007127//meiosis I;GO:0007599//hemostasis gi|568979145|ref|XP_006515688.1|/0/PREDICTED: DNA repair protein RAD51 homolog 2 isoform X10 [Mus musculus] 319478 5619 0.303333333 0.26 -0.222392421 Down 0.121657452 Cxxc4 CXXC finger 4 K03344|1|4e-142|509|mmu:319478|Dvl-binding protein IDAX - - - gi|365812519|ref|NP_001004367.2|/3.12333e-141/CXXC-type zinc finger protein 4 [Mus musculus] 19046 4024 64.67333333 65.67666667 0.022209937 Up 0.121638648 Ppp1cb "protein phosphatase 1, catalytic subunit, beta isoform" K06269|1|0.0|672|gja:107124492|serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] GO:0008287//protein serine/threonine phosphatase complex;GO:0035097//histone methyltransferase complex;GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0019900//kinase binding;GO:0004722//protein serine/threonine phosphatase activity GO:0005980//glycogen catabolic process;GO:0007155//cell adhesion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0005978//glycogen biosynthetic process;GO:0006464//cellular protein modification process;GO:0006641//triglyceride metabolic process "gi|50513466|pdb|1S70|A/0/Chain A, Complex Between Protein Ser/thr Phosphatase-1 (delta) And The Myosin Phosphatase Targeting Subunit 1 (mypt1)" 231413 2533.87 74.13333333 75.07666667 0.018242215 Up 0.121460002 Grsf1 G-rich RNA sequence binding factor 1 K12898|1|3e-73|279|xtr:100151736|heterogeneous nuclear ribonucleoprotein F/H GO:0043231//intracellular membrane-bounded organelle GO:0036094//small molecule binding GO:0003002//regionalization;GO:0002009//morphogenesis of an epithelium gi|674032416|ref|XP_008827734.1|/0/PREDICTED: G-rich sequence factor 1 [Nannospalax galili] 232440 1827 9.863333333 9.666666667 -0.029056796 Down 0.1214506 H2afj "H2A histone family, member J" K11251|1|2e-64|249|rno:690795|histone H2A - - - - 76478 1685.38 9.216666667 9.413333333 0.030460608 Up 0.1214506 Haus8 "4HAUS augmin-like complex, subunit 8" K16591|1|4e-164|580|mmu:76478|HAUS augmin-like complex subunit 8 GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex - GO:0006461//protein complex assembly;GO:0031023//microtubule organizing center organization;GO:0000087//mitotic M phase;GO:0006461//protein complex assembly;GO:0031023//microtubule organizing center organization;GO:0000087//mitotic M phase gi|251823893|ref|NP_083897.2|/1.44715e-164/HAUS augmin-like complex subunit 8 isoform 2 [Mus musculus] 230082 4522 9.98 9.776666667 -0.02969715 Down 0.1214506 Nol6 nucleolar protein family 6 (RNA-associated) K14544|1|0.0|2288|mmu:230082|U3 small nucleolar RNA-associated protein 22 - - - gi|118026904|ref|NP_631982.2|/0/nucleolar protein 6 [Mus musculus] 11735 7656.29 10.16 10.35666667 0.027659339 Up 0.1214506 Ank3 "ankyrin 3, epithelial" K10380|1|0.0|1412|ngi:103746555|ankyrin GO:0044291//cell-cell contact zone;GO:0097060//synaptic membrane;GO:0000323//lytic vacuole;GO:0031674//I band;GO:0033267;GO:0005783//endoplasmic reticulum;GO:0044459;GO:0044291//cell-cell contact zone;GO:0097060//synaptic membrane;GO:0000323//lytic vacuole;GO:0031674//I band;GO:0033267;GO:0005783//endoplasmic reticulum;GO:0044459;GO:0044291//cell-cell contact zone;GO:0097060//synaptic membrane;GO:0000323//lytic vacuole;GO:0031674//I band;GO:0033267;GO:0005783//endoplasmic reticulum;GO:0044459;GO:0044291//cell-cell contact zone;GO:0097060//synaptic membrane;GO:0000323//lytic vacuole;GO:0031674//I band;GO:0033267;GO:0005783//endoplasmic reticulum;GO:0044459;GO:0044291//cell-cell contact zone;GO:0097060//synaptic membrane;GO:0000323//lytic vacuole;GO:0031674//I band;GO:0033267;GO:0005783//endoplasmic reticulum;GO:0044459;GO:0044291//cell-cell contact zone;GO:0097060//synaptic membrane;GO:0000323//lytic vacuole;GO:0031674//I band;GO:0033267;GO:0005783//endoplasmic reticulum;GO:0044459;GO:0044291//cell-cell contact zone;GO:0097060//synaptic membrane;GO:0000323//lytic vacuole;GO:0031674//I band;GO:0033267;GO:0005783//endoplasmic reticulum;GO:0044459;GO:0044291//cell-cell contact zone;GO:0097060//synaptic membrane;GO:0000323//lytic vacuole;GO:0031674//I band;GO:0033267;GO:0005783//endoplasmic reticulum;GO:0044459;GO:0044291//cell-cell contact zone;GO:0097060//synaptic membrane;GO:0000323//lytic vacuole;GO:0031674//I band;GO:0033267;GO:0005783//endoplasmic reticulum;GO:0044459 GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity;GO:0005488//binding GO:0072658;GO:0001508//action potential;GO:0007009//plasma membrane organization;GO:0090313;GO:0022607//cellular component assembly;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0022409//positive regulation of cell-cell adhesion;GO:0006935//chemotaxis;GO:0010644//cell communication by electrical coupling;GO:0072658;GO:0001508//action potential;GO:0007009//plasma membrane organization;GO:0090313;GO:0022607//cellular component assembly;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0022409//positive regulation of cell-cell adhesion;GO:0006935//chemotaxis;GO:0010644//cell communication by electrical coupling;GO:0072658;GO:0001508//action potential;GO:0007009//plasma membrane organization;GO:0090313;GO:0022607//cellular component assembly;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0022409//positive regulation of cell-cell adhesion;GO:0006935//chemotaxis;GO:0010644//cell communication by electrical coupling;GO:0072658;GO:0001508//action potential;GO:0007009//plasma membrane organization;GO:0090313;GO:0022607//cellular component assembly;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0022409//positive regulation of cell-cell adhesion;GO:0006935//chemotaxis;GO:0010644//cell communication by electrical coupling;GO:0072658;GO:0001508//action potential;GO:0007009//plasma membrane organization;GO:0090313;GO:0022607//cellular component assembly;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0022409//positive regulation of cell-cell adhesion;GO:0006935//chemotaxis;GO:0010644//cell communication by electrical coupling;GO:0072658;GO:0001508//action potential;GO:0007009//plasma membrane organization;GO:0090313;GO:0022607//cellular component assembly;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0022409//positive regulation of cell-cell adhesion;GO:0006935//chemotaxis;GO:0010644//cell communication by electrical coupling;GO:0072658;GO:0001508//action potential;GO:0007009//plasma membrane organization;GO:0090313;GO:0022607//cellular component assembly;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0022409//positive regulation of cell-cell adhesion;GO:0006935//chemotaxis;GO:0010644//cell communication by electrical coupling;GO:0072658;GO:0001508//action potential;GO:0007009//plasma membrane organization;GO:0090313;GO:0022607//cellular component assembly;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0022409//positive regulation of cell-cell adhesion;GO:0006935//chemotaxis;GO:0010644//cell communication by electrical coupling;GO:0072658;GO:0001508//action potential;GO:0007009//plasma membrane organization;GO:0090313;GO:0022607//cellular component assembly;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0022409//positive regulation of cell-cell adhesion;GO:0006935//chemotaxis;GO:0010644//cell communication by electrical coupling gi|116256503|ref|NP_733791.2|/0/ankyrin-3 isoform e [Mus musculus] 66201 1343 11.82333333 11.62 -0.025026761 Down 0.1214506 Vta1 vesicle (multivesicular body) trafficking 1 K12199|1|2e-153|544|mmu:66201|vacuolar protein sorting-associated protein VTA1 GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding GO:0044765//single-organism transport;GO:0044763;GO:0045184//establishment of protein localization gi|27754140|ref|NP_079694.2|/1.59357e-152/vacuolar protein sorting-associated protein VTA1 homolog [Mus musculus] 67845 2265 10.59666667 10.4 -0.027026987 Down 0.1214506 Rnf115 ring finger protein 115 K11982|1|5e-176|620|mmu:67845|E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27] GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0016567//protein ubiquitination gi|170172564|ref|NP_080682.3|/4.51602e-175/E3 ubiquitin-protein ligase RNF115 [Mus musculus] 75422 947.96 10.71 10.91 0.026692622 Up 0.1214506 Mettl5 methyltransferase like 5 K07579|1|9e-47|155|dme:Dmel_CG9666|putative methylase - GO:0016741;GO:0016741 GO:0008152//metabolic process;GO:0008152//metabolic process gi|166795289|ref|NP_083556.2|/2.48278e-108/methyltransferase-like protein 5 [Mus musculus] 77031 4537.6 8.813333333 9.016666667 0.032906417 Up 0.1214506 Slc9a8 "solute carrier family 9 (sodium/hydrogen exchanger), member 8" "K14724|1|0.0|365|cmk:103172846|solute carrier family 9 (sodium/hydrogen exchanger), member 8" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005451//monovalent cation:proton antiporter activity;GO:0005451//monovalent cation:proton antiporter activity;GO:0005451//monovalent cation:proton antiporter activity;GO:0005451//monovalent cation:proton antiporter activity GO:0006814//sodium ion transport;GO:0006818//hydrogen transport;GO:0030641//regulation of cellular pH;GO:0006814//sodium ion transport;GO:0006818//hydrogen transport;GO:0030641//regulation of cellular pH;GO:0006814//sodium ion transport;GO:0006818//hydrogen transport;GO:0030641//regulation of cellular pH;GO:0006814//sodium ion transport;GO:0006818//hydrogen transport;GO:0030641//regulation of cellular pH gi|625198493|ref|XP_007641284.1|/0/PREDICTED: sodium/hydrogen exchanger 8 isoform X1 [Cricetulus griseus] 226139 4798 10.63666667 10.43666667 -0.0273851 Down 0.1214506 Cox15 cytochrome c oxidase assembly protein 15 K02259|1|0.0|806|mmu:226139|cytochrome c oxidase assembly protein subunit 15 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane GO:0015002//heme-copper terminal oxidase activity GO:0006783//heme biosynthetic process;GO:0043623//cellular protein complex assembly gi|31541932|ref|NP_659123.2|/0/cytochrome c oxidase assembly protein COX15 homolog [Mus musculus] 73137 4801 9.173333333 9.376666667 0.031629083 Up 0.1214506 Prrc1 proline-rich coiled-coil 1 - GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding - gi|110625811|ref|NP_082723.2|/0/protein PRRC1 [Mus musculus] 30877 1935 8.81 8.613333333 -0.032570355 Down 0.1214506 Gnl3 guanine nucleotide binding protein-like 3 (nucleolar) K14538|1|0.0|937|mmu:30877|nuclear GTP-binding protein GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0032550;GO:0032550 GO:0008283//cell proliferation;GO:0008283//cell proliferation "gi|148692838|gb|EDL24785.1|/0/guanine nucleotide binding protein-like 3 (nucleolar), isoform CRA_a, partial [Mus musculus]" 114255 2604 10.15333333 10.35 0.027677327 Up 0.1214506 Dok4 docking protein 4 K14752|1|8e-14|82.0|pbi:103059880|docking protein 1;K20234|5|1e-12|78.2|phi:102113335|docking protein 2 - "GO:0004871//signal transducer activity;GO:0008289//lipid binding;GO:0005102//receptor binding;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0048731//system development;GO:0006796//phosphate-containing compound metabolic process;GO:0007167//enzyme linked receptor protein signaling pathway gi|16716573|ref|NP_444476.1|/0/docking protein 4 [Mus musculus] 69085 1544 8.046666667 8.243333333 0.034836564 Up 0.1214506 Zcchc9 "zinc finger, CCHC domain containing 9" K17578|1|9e-153|542|mmu:69085|zinc finger CCHC domain-containing protein 9 - GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0010921//regulation of phosphatase activity "gi|19353581|gb|AAH24496.1|/3.28541e-152/Zinc finger, CCHC domain containing 9 [Mus musculus]" 66264 856 9.363333333 9.56 0.0299884 Up 0.1214506 Ccdc28b coiled coil domain containing 28B - GO:0005815//microtubule organizing center - GO:0010927 gi|664725951|ref|XP_008520121.1|/9.90144e-92/PREDICTED: coiled-coil domain-containing protein 28B [Equus przewalskii] 16924 2582.7 8.213333333 8.016666667 -0.034965362 Down 0.1214506 Lnx1 ligand of numb-protein X 1 K10692|1|0.0|1198|mmu:16924|ligand of Numb protein X 1/2 [EC:2.3.2.27] GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding;GO:0003824//catalytic activity GO:0019941//modification-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0051259//protein oligomerization;GO:0019941//modification-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0051259//protein oligomerization;GO:0019941//modification-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0051259//protein oligomerization;GO:0019941//modification-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0051259//protein oligomerization;GO:0019941//modification-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0051259//protein oligomerization gi|227330612|ref|NP_034857.3|/0/E3 ubiquitin-protein ligase LNX isoform 2 precursor [Mus musculus] 18679 5955.71 10.27333333 10.47666667 0.02827541 Up 0.1214506 Phka1 phosphorylase kinase alpha 1 K07190|1|0.0|2233|mmu:18679|phosphorylase kinase alpha/beta subunit GO:0043234//protein complex;GO:0016020//membrane;GO:0043234//protein complex;GO:0016020//membrane "GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0005515//protein binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0005515//protein binding;GO:0004683//calmodulin-dependent protein kinase activity" GO:0006073//cellular glucan metabolic process;GO:0006468//protein phosphorylation;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006073//cellular glucan metabolic process;GO:0006468//protein phosphorylation;GO:0006656//phosphatidylcholine biosynthetic process "gi|153945788|ref|NP_766609.2|/0/phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform 2 [Mus musculus]" 20648 2115 87.84333333 88.77 0.015139397 Up 0.121422393 Snta1 "syntrophin, acidic 1" K12196|1|8e-86|320|pps:100979126|vacuolar protein-sorting-associated protein 4;K00431|2|8e-22|108|ola:101156451|thyroid peroxidase [EC:1.11.1.8];K14548|3|1e-15|87.4|tgu:100229140|U3 small nucleolar RNA-associated protein 4;K12076|4|1e-09|67.8|bfo:BRAFLDRAFT_255838|disks large protein 1 - - - "gi|148674121|gb|EDL06068.1|/0/syntrophin, acidic 1, isoform CRA_a, partial [Mus musculus]" 57753 3977 2.14 2.046666667 -0.064334642 Down 0.121394186 Noc3l NOC3 like DNA replication regulator K14834|1|0.0|1415|mmu:57753|nucleolar complex protein 3 GO:0016604//nuclear body - GO:0030154//cell differentiation gi|188497644|ref|NP_067290.2|/0/nucleolar complex protein 3 homolog [Mus musculus] 69709 4013 2.173333333 2.26 0.056413309 Up 0.121394186 Ptrhd1 peptidyl-tRNA hydrolase domain containing 1 "K04794|1|1e-24|119|xla:779309|peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29];K14394|2|4e-13|80.5|cbr:CBG13912|low molecular weight phosphotyrosine protein phosphatase [EC:3.1.3.2 3.1.3.48]" GO:0044424 GO:0003824//catalytic activity GO:0044710 "gi|148709196|gb|EDL41142.1|/4.8501e-157/RIKEN cDNA 4833439L19, isoform CRA_c, partial [Mus musculus]" 243308 3157 2.163333333 2.25 0.056669024 Up 0.121394186 A430033K04Rik RIKEN cDNA A430033K04 gene K09228|1|0.0|1453|mmu:243308|KRAB domain-containing zinc finger protein - - - gi|163914377|ref|NP_898846.2|/0/uncharacterized protein LOC243308 [Mus musculus] 98711 2295 2.043333333 2.13 0.059928857 Up 0.121394186 Rdh10 retinol dehydrogenase 10 (all-trans) K11151|1|0.0|637|mmu:98711|retinol dehydrogenase 10 [EC:1.1.1.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane GO:0008106//alcohol dehydrogenase (NADP+) activity;GO:0036094//small molecule binding GO:0001523//retinoid metabolic process;GO:0001822//kidney development;GO:0043010//camera-type eye development;GO:0050953//sensory perception of light stimulus;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0030326//embryonic limb morphogenesis;GO:0043009//chordate embryonic development;GO:0014031//mesenchymal cell development;GO:0016102//diterpenoid biosynthetic process;GO:0016331//morphogenesis of embryonic epithelium gi|25141231|ref|NP_598593.1|/4.73188e-180/retinol dehydrogenase 10 [Mus musculus] 28071 2324 2.28 2.373333333 0.057880916 Up 0.121394186 Twistnb twist basic helix-loop-helix transcription factor 1 neighbor K03004|1|8e-154|546|mmu:28071|DNA-directed RNA polymerase I subunit RPA43 - - - - 74393 3548 2.143333333 2.233333333 0.059342358 Up 0.121394186 Map10 microtubule-associated protein 10 - GO:0005874//microtubule;GO:0000922//spindle pole;GO:0051233//spindle midzone GO:0015631//tubulin binding GO:0000910//cytokinesis;GO:0051255//spindle midzone assembly gi|33859726|ref|NP_083184.1|/0/microtubule-associated protein 10 [Mus musculus] 66865 3125 52.91666667 53.82666667 0.0245989 Up 0.121356576 Pmpca peptidase (mitochondrial processing) alpha K01412|1|0.0|963|mmu:66865|mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64] GO:0019866//organelle inner membrane;GO:0044429 GO:0043169//cation binding;GO:0004175//endopeptidase activity GO:0006605//protein targeting;GO:0019538//protein metabolic process gi|27502349|ref|NP_775272.1|/0/mitochondrial-processing peptidase subunit alpha precursor [Mus musculus] 67839 3271.8 77.10333333 76.20666667 -0.01687602 Down 0.121328369 Gpsm1 "G-protein signalling modulator 1 (AGS3-like, C. elegans)" K15839|1|0.0|1324|mmu:67839|G-protein signaling modulator 1 GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031090//organelle membrane GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0048869//cellular developmental process;GO:0048731//system development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0007186//G-protein coupled receptor signaling pathway "gi|148676352|gb|EDL08299.1|/0/G-protein signalling modulator 1 (AGS3-like, C. elegans), isoform CRA_c, partial [Mus musculus]" 100121 3656.21 4.646666667 4.78 0.040814463 Up 0.121309564 Tdrd7 tudor domain containing 7 K18405|1|0.0|2157|mmu:100121|tudor domain-containing protein 1/4/6/7 GO:0035770//ribonucleoprotein granule;GO:0044429;GO:0035770//ribonucleoprotein granule;GO:0044429 GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0005515//protein binding GO:0048869//cellular developmental process;GO:0010468//regulation of gene expression;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0002088//lens development in camera-type eye;GO:0048869//cellular developmental process;GO:0010468//regulation of gene expression;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction;GO:0002088//lens development in camera-type eye gi|594191009|ref|NP_001277404.1|/0/tudor domain-containing protein 7 isoform 1 [Mus musculus] 75089 6446 4.8 4.67 -0.039611856 Down 0.121309564 Uhrf1bp1l UHRF1 (ICBP90) binding protein 1-like K19526|1|7e-06|57.0|hmg:100199203|vacuolar protein sorting-associated protein 13B - - - gi|26006205|dbj|BAC41445.1|/0/mKIAA0701 protein [Mus musculus] 74551 3400 5.136666667 5.27 0.036970506 Up 0.121309564 Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) K01596|1|0.0|1345|mmu:74551|phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] - - - "gi|148704343|gb|EDL36290.1|/0/phosphoenolpyruvate carboxykinase 2 (mitochondrial), isoform CRA_b, partial [Mus musculus]" 78651 3778.09 5.163333333 5.033333333 -0.036788595 Down 0.121309564 Lsm6 "LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated" K12625|1|8e-39|165|lcm:102367496|U6 snRNA-associated Sm-like protein LSm6 - - - - 74142 2970 61.89666667 62.77 0.020213491 Up 0.121243747 Lonp1 "lon peptidase 1, mitochondrial" K08675|1|0.0|1733|mmu:74142|Lon-like ATP-dependent protease [EC:3.4.21.-] - - - "gi|148706233|gb|EDL38180.1|/0/protease, serine, 15, isoform CRA_b, partial [Mus musculus]" 98758 2281.83 63.50666667 64.37666667 0.01962983 Up 0.121243747 Hnrnpf heterogeneous nuclear ribonucleoprotein F K12898|1|0.0|796|rno:64200|heterogeneous nuclear ribonucleoprotein F/H GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0008134//transcription factor binding;GO:0036094//small molecule binding;GO:0003723//RNA binding;GO:0008134//transcription factor binding;GO:0036094//small molecule binding;GO:0003723//RNA binding;GO:0008134//transcription factor binding;GO:0036094//small molecule binding;GO:0003723//RNA binding;GO:0008134//transcription factor binding;GO:0036094//small molecule binding;GO:0003723//RNA binding;GO:0008134//transcription factor binding;GO:0036094//small molecule binding;GO:0003723//RNA binding;GO:0008134//transcription factor binding;GO:0036094//small molecule binding;GO:0003723//RNA binding;GO:0008134//transcription factor binding;GO:0036094//small molecule binding GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377;GO:0000377 gi|26345420|dbj|BAC36361.1|/0/unnamed protein product [Mus musculus] 17436 3257.77 49.06666667 49.92333333 0.024970999 Up 0.121187333 Me1 "malic enzyme 1, NADP(+)-dependent, cytosolic" K00029|1|0.0|1038|mmu:17436|malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0004470//malic enzyme activity;GO:0000166//nucleotide binding;GO:0046914//transition metal ion binding;GO:0004470//malic enzyme activity;GO:0000166//nucleotide binding GO:0009719;GO:0043648//dicarboxylic acid metabolic process;GO:0051259//protein oligomerization;GO:0009719;GO:0043648//dicarboxylic acid metabolic process;GO:0051259//protein oligomerization gi|312147392|ref|NP_001185862.1|/0/NADP-dependent malic enzyme isoform 2 [Mus musculus] 226594 2663.22 63.63 64.46666667 0.018846267 Up 0.121112114 Rcsd1 RCSD domain containing 1 K18615|1|0.0|776|mmu:226594|CapZ-interacting protein - - - - 17076 5172 0.066666667 0.096666667 0.5360529 Up 0.12101809 Ly75 lymphocyte antigen 75 K06559|1|0.0|3613|mmu:17076|lymphocyte antigen 75 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0016192//vesicle-mediated transport gi|148747179|ref|NP_038853.2|/0/lymphocyte antigen 75 precursor [Mus musculus] 50905 2061 0.096666667 0.066666667 -0.5360529 Down 0.12101809 Il17rb interleukin 17 receptor B K05165|1|0.0|971|mmu:50905|interleukin 17 receptor B GO:0016021//integral component of membrane;GO:0044424 - GO:0007166//cell surface receptor signaling pathway "gi|148692799|gb|EDL24746.1|/0/interleukin 17 receptor B, isoform CRA_b, partial [Mus musculus]" 68947 2397 0.066666667 0.096666667 0.5360529 Up 0.12101809 Chst8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 K09672|1|0.0|793|mmu:68947|carbohydrate 4-sulfotransferase 8 [EC:2.8.2.-] GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008146//sulfotransferase activity GO:0006029//proteoglycan metabolic process;GO:0016485//protein processing;GO:0009058//biosynthetic process;GO:0007399//nervous system development;GO:0044723 gi|255522962|ref|NP_780349.3|/0/carbohydrate sulfotransferase 8 [Mus musculus] 192136 1727 0.06 0.086666667 0.530514717 Up 0.12101809 Sugct succinyl-CoA glutarate-CoA transferase K18703|1|0.0|842|mmu:192136|succinate---hydroxymethylglutarate CoA-transferase [EC:2.8.3.13] GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity - gi|261399886|ref|NP_619595.3|/0/succinate--hydroxymethylglutarate CoA-transferase [Mus musculus] 381413 3911 0.1 0.07 -0.514573173 Down 0.12101809 Gpr176 G protein-coupled receptor 176 K08442|1|0.0|988|mmu:381413|G protein-coupled receptor 176 GO:0016021//integral component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling gi|148695958|gb|EDL27905.1|/0/G protein-coupled receptor 176 [Mus musculus] 58182 4073 0.086666667 0.06 -0.530514717 Down 0.12101809 Prokr1 prokineticin receptor 1 K08379|1|0.0|718|mmu:58182|prokineticin receptor 1 GO:0031224//intrinsic component of membrane GO:0008188//neuropeptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0001568//blood vessel development;GO:0048511//rhythmic process;GO:0006915//apoptotic process gi|40254343|ref|NP_067356.2|/0/prokineticin receptor 1 [Mus musculus] 70433 5217 0.073333333 0.106666667 0.540568381 Up 0.12101809 Draxin dorsal inhibitory axon guidance protein - - - GO:0021515//cell differentiation in spinal cord;GO:0007420//brain development;GO:0006935//chemotaxis;GO:0030178//negative regulation of Wnt signaling pathway gi|568931882|ref|XP_006539233.1|/1.73076e-170/PREDICTED: draxin isoform X1 [Mus musculus] 73293 1800 0.083333333 0.056666667 -0.556393349 Down 0.12101809 Ccdc103 coiled-coil domain containing 103 - GO:0043231//intracellular membrane-bounded organelle GO:0042802//identical protein binding GO:0007018//microtubule-based movement;GO:0007368//determination of left/right symmetry;GO:0070286//axonemal dynein complex assembly gi|58037317|ref|NP_082768.1|/1.60553e-100/coiled-coil domain-containing protein 103 [Mus musculus] 68509 1492 0.07 0.1 0.514573173 Up 0.12101809 Ptx4 pentraxin 4 K05016|1|3e-25|119|apla:101803337|chloride channel 7;K17495|2|1e-23|113|tca:103312732|CUB and sushi domain-containing protein - - - gi|254540103|ref|NP_081023.1|/0/pentraxin-4 isoform 1 precursor [Mus musculus] 408059 1683 0.063333333 0.09 0.506959989 Up 0.12101809 BC049352 cDNA sequence BC049352 - - - - "gi|148693695|gb|EDL25642.1|/3.95267e-45/mCG145425, partial [Mus musculus]" 320377 1538 0.066666667 0.096666667 0.5360529 Up 0.12101809 9330175E14Rik RIKEN cDNA 9330175E14 gene - - - - - 18705 3549 0.056666667 0.083333333 0.556393349 Up 0.12101809 Pik3c2g "phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide" K00923|1|0.0|1332|mmu:18705|phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154] GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0016020//membrane GO:0032550;GO:0005543//phospholipid binding;GO:0016307//phosphatidylinositol phosphate kinase activity GO:0046488//phosphatidylinositol metabolic process;GO:0048017//inositol lipid-mediated signaling;GO:0042221//response to chemical gi|158508506|ref|NP_035214.2|/0/phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform 2 [Mus musculus] 242584 3793 0.103333333 0.07 -0.561878888 Down 0.12101809 Wdr78 WD repeat domain 78 "K10409|1|4e-59|233|tgu:100223289|dynein intermediate chain 1, axonemal" - - - gi|334688818|ref|NP_666366.4|/0/WD repeat-containing protein 78 [Mus musculus] 666661 8431 0.06 0.086666667 0.530514717 Up 0.12101809 Gm8221 apolipoprotein L 7c pseudogene K14480|1|8e-99|366|mmu:108956|apolipoprotein L - - - "gi|148697697|gb|EDL29644.1|/4.82566e-109/mCG1032535, partial [Mus musculus]" 16147 2476 0.063333333 0.09 0.506959989 Up 0.12101809 Ihh Indian hedgehog K11989|1|0.0|762|mmu:16147|indian hedgehog - - - - 74076 1633 0.09 0.063333333 -0.506959989 Down 0.12101809 4933406C10Rik RIKEN cDNA 4933406C10 gene - - - - - 170786 1484 0.07 0.103333333 0.561878888 Up 0.12101809 Cd209a CD209a antigen K06563|1|1e-131|472|mmu:170786|CD209 antigen GO:0031224//intrinsic component of membrane;GO:0044464 GO:0043169//cation binding GO:0042098//T cell proliferation;GO:0016192//vesicle-mediated transport gi|18875404|ref|NP_573501.1|/1.15509e-130/CD209 antigen-like protein A [Mus musculus] 217316 3020 0.093333333 0.063333333 -0.559427409 Down 0.12101809 Slc16a5 "solute carrier family 16 (monocarboxylic acid transporters), member 5" "K08182|1|0.0|909|mmu:217316|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 5" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0051234//establishment of localization;GO:0044763 gi|124286852|ref|NP_001074403.1|/0/monocarboxylate transporter 6 [Mus musculus] 68544 934 59.82666667 60.64333333 0.019560372 Up 0.120971078 2310036O22Rik RIKEN cDNA 2310036O22 gene - - - - gi|625197103|ref|XP_003501959.2|/3.92618e-47/PREDICTED: uncharacterized protein C19orf43 homolog isoform X1 [Cricetulus griseus] 67851 898 76.19 75.38333333 -0.015356065 Down 0.120942871 1700021F05Rik RIKEN cDNA 1700021F05 gene K12662|1|2e-08|62.0|smm:Smp_169060|U4/U6 small nuclear ribonucleoprotein PRP4 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding - gi|13385904|ref|NP_080687.1|/2.84474e-100/uncharacterized protein C6orf203 homolog [Mus musculus] 66532 982 0.566666667 0.513333333 -0.142604395 Down 0.120914664 Rep15 RAB15 effector protein K20243|1|8e-131|468|mmu:66532|Rab15 effector protein GO:0005769//early endosome - - gi|13385078|ref|NP_079896.1|/6.82566e-130/rab15 effector protein [Mus musculus] 71819 3439 0.513333333 0.466666667 -0.137503524 Down 0.120914664 Kif23 kinesin family member 23 K17387|1|0.0|1808|mmu:71819|kinesin family member 23 - - - gi|256985168|ref|NP_077207.3|/0/kinesin-like protein KIF23 [Mus musculus] 74732 2146 0.543333333 0.596666667 0.135087623 Up 0.120914664 Stx11 syntaxin 11 K08487|1|5e-150|534|mmu:74732|syntaxin 11 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0015031//protein transport;GO:0015031//protein transport;GO:0015031//protein transport gi|254675350|ref|NP_083351.1|/3.97497e-149/syntaxin-11 [Mus musculus] 380674 3648 0.51 0.563333333 0.143491594 Up 0.120914664 Rdh18-ps "retinol dehydrogenase 18, pseudogene" K11154|1|2e-141|380|mmu:103142|retinol dehydrogenase 16 [EC:1.1.1.-] - - - - 71445 3732 0.473333333 0.523333333 0.144873629 Up 0.120914664 5530601H04Rik RIKEN cDNA 5530601H04 gene - - - - - 22701 3553 0.52 0.473333333 -0.135655099 Down 0.120914664 Zfp41 zinc finger protein 41 K09228|1|2e-60|237|myb:102248423|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated" gi|148697534|gb|EDL29481.1|/1.98831e-82/mCG22117 [Mus musculus] 52028 5646 1.34 1.27 -0.077404504 Down 0.120905262 Bbs1 Bardet-Biedl syndrome 1 (human) K16746|1|0.0|1071|mmu:52028|Bardet-Biedl syndrome 1 protein GO:0043234//protein complex;GO:0031090//organelle membrane;GO:0044424 GO:0005488//binding GO:0001894//tissue homeostasis;GO:0007601//visual perception;GO:0042384//cilium assembly;GO:0006886//intracellular protein transport gi|148701131|gb|EDL33078.1|/0/mCG8379 [Mus musculus] 231214 5463 1.33 1.26 -0.078002512 Down 0.120905262 Cc2d2a coiled-coil and C2 domain containing 2A K19352|1|0.0|2951|mmu:231214|coiled-coil and C2 domain-containing protein 2A - - - - 18817 2214 1.286666667 1.216666667 -0.080704384 Down 0.120905262 Plk1 polo-like kinase 1 K06631|1|0.0|1057|mmu:18817|polo-like kinase 1 [EC:2.7.11.21] - - - - 78070 2809.11 1.226666667 1.16 -0.08061846 Down 0.120905262 Cpt1c carnitine palmitoyltransferase 1c "K19524|1|0.0|1566|mmu:78070|carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]" GO:0031966//mitochondrial membrane;GO:0008328//ionotropic glutamate receptor complex;GO:0031966//mitochondrial membrane;GO:0008328//ionotropic glutamate receptor complex GO:0016740//transferase activity;GO:0016740//transferase activity GO:0009062//fatty acid catabolic process;GO:0006577//amino-acid betaine metabolic process;GO:0009062//fatty acid catabolic process;GO:0006577//amino-acid betaine metabolic process "gi|24211027|ref|NP_710146.1|/0/carnitine O-palmitoyltransferase 1, brain isoform [Mus musculus]" 214133 9199 1.183333333 1.116666667 -0.083657929 Down 0.120905262 Tet2 tet methylcytosine dioxygenase 2 K13097|1|3e-132|477|lcm:102366582|methylcytosine dioxygenase [EC:1.14.11.-] - - - gi|157057152|ref|NP_001035490.2|/0/methylcytosine dioxygenase TET2 [Mus musculus] 20393 2499.8 75.66 76.46333333 0.015237318 Up 0.120895859 Sgk1 serum/glucocorticoid regulated kinase 1 K13302|1|0.0|819|mmu:20393|serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection;GO:0044444//cytoplasmic part GO:0032550;GO:0004672//protein kinase activity;GO:0005543//phospholipid binding;GO:0016247//channel regulator activity;GO:0004672//protein kinase activity;GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0005543//phospholipid binding;GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0019901//protein kinase binding "GO:0007613//memory;GO:0003096//renal sodium ion transport;GO:0006355//regulation of transcription, DNA-templated;GO:0008015//blood circulation;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0001696//gastric acid secretion;GO:0032409;GO:0006464//cellular protein modification process;GO:0016049//cell growth;GO:0033554//cellular response to stress;GO:0016477//cell migration;GO:0032868//response to insulin;GO:0002028//regulation of sodium ion transport;GO:0006915//apoptotic process;GO:0031175//neuron projection development;GO:0008104//protein localization;GO:0016049//cell growth;GO:0007613//memory;GO:0031346//positive regulation of cell projection organization;GO:0007049//cell cycle;GO:0031111//negative regulation of microtubule polymerization or depolymerization;GO:0033554//cellular response to stress;GO:0007632//visual behavior;GO:0043401//steroid hormone mediated signaling pathway;GO:0006875//cellular metal ion homeostasis;GO:0006468//protein phosphorylation;GO:0032868//response to insulin;GO:0002028//regulation of sodium ion transport;GO:0006915//apoptotic process;GO:0031175//neuron projection development;GO:0008104//protein localization;GO:0016049//cell growth;GO:0007613//memory;GO:0031346//positive regulation of cell projection organization;GO:0007049//cell cycle;GO:0031111//negative regulation of microtubule polymerization or depolymerization;GO:0033554//cellular response to stress;GO:0007632//visual behavior;GO:0043401//steroid hormone mediated signaling pathway;GO:0006875//cellular metal ion homeostasis;GO:0006468//protein phosphorylation;GO:0032868//response to insulin;GO:0002028//regulation of sodium ion transport;GO:0006915//apoptotic process;GO:0031175//neuron projection development;GO:0008104//protein localization;GO:0016049//cell growth;GO:0007613//memory;GO:0031346//positive regulation of cell projection organization;GO:0007049//cell cycle;GO:0031111//negative regulation of microtubule polymerization or depolymerization;GO:0033554//cellular response to stress;GO:0007632//visual behavior;GO:0043401//steroid hormone mediated signaling pathway;GO:0006875//cellular metal ion homeostasis;GO:0006468//protein phosphorylation;GO:0032868//response to insulin;GO:0002028//regulation of sodium ion transport;GO:0006915//apoptotic process;GO:0031175//neuron projection development;GO:0008104//protein localization;GO:0016049//cell growth;GO:0007613//memory;GO:0031346//positive regulation of cell projection organization;GO:0007049//cell cycle;GO:0031111//negative regulation of microtubule polymerization or depolymerization;GO:0033554//cellular response to stress;GO:0007632//visual behavior;GO:0043401//steroid hormone mediated signaling pathway;GO:0006875//cellular metal ion homeostasis;GO:0006468//protein phosphorylation" gi|257796265|ref|NP_001155317.2|/0/serine/threonine-protein kinase Sgk1 isoform a [Mus musculus] 18824 1178 65.60666667 64.81 -0.017625989 Down 0.120895859 Plp2 proteolipid protein 2 - - - - - 71738 3338 0.88 0.82 -0.101879614 Down 0.12082064 Mamdc2 MAM domain containing 2 K18762|1|5e-35|152|ecb:100146768|zygote arrest protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix GO:0097367//carbohydrate derivative binding GO:0018149//peptide cross-linking gi|33469047|ref|NP_777282.1|/0/MAM domain-containing protein 2 precursor [Mus musculus] 218343 5381 0.876666667 0.94 0.100632363 Up 0.12082064 Ttc37 tetratricopeptide repeat domain 37 K12600|1|0.0|3033|mmu:218343|superkiller protein 3 - - - gi|124486883|ref|NP_001074821.1|/0/tetratricopeptide repeat protein 37 [Mus musculus] 11783 6497 0.84 0.903333333 0.104869118 Up 0.12082064 Apaf1 apoptotic peptidase activating factor 1 K02084|1|0.0|2520|mmu:11783|apoptotic protease-activating factor GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0016504//peptidase activator activity;GO:0032550;GO:0005515//protein binding;GO:0016504//peptidase activator activity;GO:0032550;GO:0005515//protein binding;GO:0016504//peptidase activator activity;GO:0032550;GO:0005515//protein binding "GO:0070997//neuron death;GO:0071363//cellular response to growth factor stimulus;GO:0014020;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007420//brain development;GO:0051259//protein oligomerization;GO:0012502//induction of programmed cell death;GO:0048869//cellular developmental process;GO:0010658;GO:0006950//response to stress;GO:0031667//response to nutrient levels;GO:0070997//neuron death;GO:0071363//cellular response to growth factor stimulus;GO:0014020;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007420//brain development;GO:0051259//protein oligomerization;GO:0012502//induction of programmed cell death;GO:0048869//cellular developmental process;GO:0010658;GO:0006950//response to stress;GO:0031667//response to nutrient levels;GO:0070997//neuron death;GO:0071363//cellular response to growth factor stimulus;GO:0014020;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007420//brain development;GO:0051259//protein oligomerization;GO:0012502//induction of programmed cell death;GO:0048869//cellular developmental process;GO:0010658;GO:0006950//response to stress;GO:0031667//response to nutrient levels" gi|60360324|dbj|BAD90406.1|/0/mKIAA0413 protein [Mus musculus] 319651 7130 0.923333333 0.86 -0.102514911 Down 0.12082064 Usp37 ubiquitin specific peptidase 37 K11850|1|0.0|1740|mmu:319651|ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12] - GO:0019783//ubiquitin-like protein-specific protease activity;GO:0004175//endopeptidase activity;GO:0016790//thiolester hydrolase activity;GO:0019900//kinase binding GO:0016579//protein deubiquitination;GO:0019941//modification-dependent protein catabolic process;GO:0000087//mitotic M phase gi|893570402|ref|NP_001297591.1|/0/ubiquitin carboxyl-terminal hydrolase 37 isoform 2 [Mus musculus] 72634 2665 0.846666667 0.79 -0.099941438 Down 0.12082064 Tdrkh tudor and KH domain containing protein K18406|1|0.0|1016|mmu:72634|tudor domain-containing protein 2 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding - "gi|148706782|gb|EDL38729.1|/0/mCG5013, isoform CRA_b, partial [Mus musculus]" 68144 6021 0.856666667 0.92 0.102899908 Up 0.12082064 5031426D15Rik RIKEN cDNA 5031426D15 gene - - - - "gi|148701441|gb|EDL33388.1|/4.11197e-14/mCG1045525, partial [Mus musculus]" 20650 4423 0.89 0.83 -0.100694 Down 0.12082064 Sntb2 "syntrophin, basic 2" K12196|1|0.0|695|pps:100979126|vacuolar protein-sorting-associated protein 4;K00431|2|2e-18|98.2|ola:101156451|thyroid peroxidase [EC:1.11.1.8];K14548|3|4e-15|87.0|tgu:100229140|U3 small nucleolar RNA-associated protein 4;K12076|4|4e-10|70.5|acs:100556749|disks large protein 1 GO:0043234//protein complex;GO:0030133//transport vesicle;GO:0015630//microtubule cytoskeleton GO:0008289//lipid binding;GO:0008092//cytoskeletal protein binding - gi|6678059|ref|NP_033255.1|/0/beta-2-syntrophin [Mus musculus] 54720 2270.12 54.17666667 54.94333333 0.020272808 Up 0.120783031 Rcan1 regulator of calcineurin 1 K17901|1|2e-104|382|mmu:54720|calcipressin-1 GO:0044424;GO:0043231//intracellular membrane-bounded organelle GO:0019903//protein phosphatase binding GO:0048545//response to steroid hormone;GO:0019932//second-messenger-mediated signaling;GO:0051145//smooth muscle cell differentiation;GO:0007519//skeletal muscle tissue development;GO:0010921//regulation of phosphatase activity;GO:0048545//response to steroid hormone;GO:0019932//second-messenger-mediated signaling;GO:0051145//smooth muscle cell differentiation;GO:0007519//skeletal muscle tissue development;GO:0009605//response to external stimulus;GO:0010921//regulation of phosphatase activity gi|125656176|ref|NP_001075018.1|/8.73814e-121/calcipressin-1 isoform 1 [Mus musculus] 17698 3840 64.71333333 63.94333333 -0.017269038 Down 0.120783031 Msn moesin K05763|1|0.0|969|mmu:17698|moesin - - - - 216792 4027 7.9 8.086666667 0.033692491 Up 0.120736019 Iba57 "IBA57 homolog, iron-sulfur cluster assembly" "K03847|1|2e-06|58.2|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - - 230757 2852.79 9.413333333 9.606666667 0.029330247 Up 0.120736019 5730409E04Rik RIKEN cDNA 5730409E04Rik gene - - - - "gi|148698334|gb|EDL30281.1|/4.95459e-105/mCG120695, isoform CRA_b, partial [Mus musculus]" 76654 2219 0.116666667 0.083333333 -0.485426827 Down 0.120736019 Upp2 uridine phosphorylase 2 K00757|1|4e-173|610|mmu:76654|uridine phosphorylase [EC:2.4.2.3] GO:0005882//intermediate filament;GO:0044444//cytoplasmic part;GO:0005882//intermediate filament;GO:0044444//cytoplasmic part;GO:0005882//intermediate filament "GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups;GO:0016763//transferase activity, transferring pentosyl groups" GO:0009117//nucleotide metabolic process;GO:0006222//UMP biosynthetic process;GO:0009112;GO:0008655//pyrimidine-containing compound salvage;GO:0006222//UMP biosynthetic process;GO:0009112;GO:0008655//pyrimidine-containing compound salvage gi|568914454|ref|XP_006498469.1|/2.73047e-177/PREDICTED: uridine phosphorylase 2 isoform X4 [Mus musculus] 71890 1249 8.826666667 9.02 0.031258717 Up 0.120736019 Mad2l2 MAD2 mitotic arrest deficient-like 2 K13728|1|1e-113|412|mmu:71890|mitotic spindle assembly checkpoint protein MAD2B GO:0031981//nuclear lumen;GO:0042575;GO:0000152//nuclear ubiquitin ligase complex;GO:0015630//microtubule cytoskeleton;GO:0031981//nuclear lumen;GO:0042575;GO:0000152//nuclear ubiquitin ligase complex;GO:0015630//microtubule cytoskeleton GO:0001085//RNA polymerase II transcription factor binding;GO:0019901//protein kinase binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0019901//protein kinase binding "GO:0045892//negative regulation of transcription, DNA-templated;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0006281//DNA repair;GO:0042770//signal transduction in response to DNA damage;GO:0033633//negative regulation of cell-cell adhesion mediated by integrin;GO:0043392//negative regulation of DNA binding;GO:0016049//cell growth;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0009895;GO:0001837//epithelial to mesenchymal transition;GO:0001934//positive regulation of protein phosphorylation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0030036//actin cytoskeleton organization;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0006281//DNA repair;GO:0042770//signal transduction in response to DNA damage;GO:0033633//negative regulation of cell-cell adhesion mediated by integrin;GO:0043392//negative regulation of DNA binding;GO:0016049//cell growth;GO:0031145//anaphase-promoting complex-dependent catabolic process;GO:0009895;GO:0001837//epithelial to mesenchymal transition;GO:0001934//positive regulation of protein phosphorylation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0030036//actin cytoskeleton organization" gi|126090494|ref|NP_082261.2|/1.16023e-116/mitotic spindle assembly checkpoint protein MAD2B [Mus musculus] 228012 4050 8.636666667 8.446666667 -0.032092491 Down 0.120736019 Tlk1 tousled-like kinase 1 K08864|1|0.0|1377|mmu:228012|tousled-like kinase [EC:2.7.11.1] - - - gi|224994273|ref|NP_766252.2|/0/serine/threonine-protein kinase tousled-like 1 [Mus musculus] 102216272 990 8.33 8.143333333 -0.032697038 Down 0.120736019 Ak6 adenylate kinase 6 K18532|1|1e-98|361|mmu:102216272|adenylate kinase [EC:2.7.4.3] GO:0044665//MLL1/2 complex;GO:0070461//SAGA-type complex;GO:0005667//transcription factor complex;GO:0016604//nuclear body;GO:0030529//intracellular ribonucleoprotein complex "GO:0032550;GO:0003712//transcription cofactor activity;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding;GO:0000975//regulatory region DNA binding;GO:0008134//transcription factor binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0008080//N-acetyltransferase activity" GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0006796//phosphate-containing compound metabolic process;GO:0031330;GO:0034097//response to cytokine;GO:0016049//cell growth;GO:0016573//histone acetylation gi|56753653|gb|AAW25029.1|/3.15968e-98/unknown [Schistosoma japonicum] 110809 5422.5 10.68666667 10.5 -0.025422597 Down 0.120736019 Srsf1 serine/arginine-rich splicing factor 1 "K12890|1|3e-80|284|ngi:103741791|splicing factor, arginine/serine-rich 1/9" GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0005681//spliceosomal complex;GO:0016604//nuclear body GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding GO:0006941//striated muscle contraction;GO:0043009//chordate embryonic development;GO:0006376//mRNA splice site selection;GO:0006405//RNA export from nucleus;GO:0006366//transcription from RNA polymerase II promoter;GO:0006941//striated muscle contraction;GO:0043009//chordate embryonic development;GO:0006376//mRNA splice site selection;GO:0006405//RNA export from nucleus;GO:0006366//transcription from RNA polymerase II promoter gi|179074|gb|AAA35564.1|/2.55178e-102/alternative [Homo sapiens] 72049 1906 0.116666667 0.083333333 -0.485426827 Down 0.120736019 Tnfrsf13c "tumor necrosis factor receptor superfamily, member 13c" K05151|1|2e-70|269|mmu:72049|tumor necrosis factor receptor superfamily member 13C GO:0031224//intrinsic component of membrane;GO:0009986//cell surface - GO:0002467//germinal center formation;GO:0030888//regulation of B cell proliferation;GO:0042095//interferon-gamma biosynthetic process;GO:0042098//T cell proliferation;GO:0031294//lymphocyte costimulation gi|16306481|ref|NP_082351.1|/1.57511e-69/tumor necrosis factor receptor superfamily member 13C [Mus musculus] 68080 1425 9.536666667 9.723333333 0.027965889 Up 0.120736019 Gpn3 GPN-loop GTPase 3 K06883|1|1e-163|578|mmu:68080|uncharacterized protein GO:0032991//macromolecular complex GO:0032550 - gi|664706725|ref|XP_008506621.1|/7.49265e-164/PREDICTED: GPN-loop GTPase 3 [Equus przewalskii] 11426 17499.89 9.163333333 9.35 0.029093864 Up 0.120736019 Macf1 microtubule-actin crosslinking factor 1 K19827|1|0.0|6940|mmu:11426|microtuble-actin crosslinking factor 1 - - - gi|312433955|ref|NP_001186065.1|/0/microtubule-actin cross-linking factor 1 isoform 1 [Mus musculus] 19878 8012 8.506666667 8.313333333 -0.033166864 Down 0.120736019 Rock2 Rho-associated coiled-coil containing protein kinase 2 K17388|1|0.0|2400|mmu:19878|Rho-associated protein kinase 2 [EC:2.7.11.1] GO:0016020//membrane;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0000922//spindle pole GO:0032550;GO:0004672//protein kinase activity;GO:0017016//Ras GTPase binding;GO:0043169//cation binding;GO:0008289//lipid binding GO:0007098//centrosome cycle;GO:0001525//angiogenesis;GO:0007265//Ras protein signal transduction;GO:0014020;GO:0010638//positive regulation of organelle organization;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0030216//keratinocyte differentiation gi|134949013|ref|NP_033098.2|/0/rho-associated protein kinase 2 [Mus musculus] 18142 2091 0.093333333 0.066666667 -0.485426827 Down 0.120736019 Npas1 neuronal PAS domain protein 1 K09098|1|0.0|927|mmu:18142|neuronal PAS domain-containing protein 1/3 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0060089;GO:0005515//protein binding "GO:0050896//response to stimulus;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication" gi|6679100|ref|NP_032744.1|/0/neuronal PAS domain-containing protein 1 [Mus musculus] 218271 2291.94 8.073333333 8.26 0.032977322 Up 0.120736019 B4galt7 "xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)" K00733|1|2e-159|565|mmu:218271|xylosylprotein 4-beta-galactosyltransferase [EC:2.4.1.133] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0035250//UDP-galactosyltransferase activity;GO:0043169//cation binding;GO:0035250//UDP-galactosyltransferase activity GO:0008285//negative regulation of cell proliferation;GO:0006023;GO:0030198//extracellular matrix organization;GO:0009100//glycoprotein metabolic process;GO:0008285//negative regulation of cell proliferation;GO:0006023;GO:0030198//extracellular matrix organization;GO:0009100//glycoprotein metabolic process "gi|148709272|gb|EDL41218.1|/3.61783e-145/xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I), isoform CRA_b, partial [Mus musculus]" 72692 3050 7.913333333 8.1 0.033636379 Up 0.120736019 Hnrnpll heterogeneous nuclear ribonucleoprotein L-like K13159|1|0.0|958|mmu:72692|heterogeneous nuclear ribonucleoprotein L - - - - 14573 3449 0.093333333 0.066666667 -0.485426827 Down 0.120736019 Gdnf glial cell line derived neurotrophic factor K05452|1|7e-101|372|mmu:14573|glial cell derived neurotrophic factor GO:0043234//protein complex;GO:0044421;GO:0043234//protein complex;GO:0044421;GO:0043234//protein complex;GO:0044421;GO:0043234//protein complex;GO:0044421 GO:0005126//cytokine receptor binding;GO:0042802//identical protein binding;GO:0070851//growth factor receptor binding;GO:0005126//cytokine receptor binding;GO:0042802//identical protein binding;GO:0070851//growth factor receptor binding;GO:0005126//cytokine receptor binding;GO:0042802//identical protein binding;GO:0070851//growth factor receptor binding;GO:0005126//cytokine receptor binding;GO:0042802//identical protein binding;GO:0070851//growth factor receptor binding "GO:0014046;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0045995//regulation of embryonic development;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0008406//gonad development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0007420//brain development;GO:0051094//positive regulation of developmental process;GO:0001667//ameboidal-type cell migration;GO:0014821;GO:0006935//chemotaxis;GO:0003156//regulation of organ formation;GO:0007626//locomotory behavior;GO:0043488//regulation of mRNA stability;GO:0043010//camera-type eye development;GO:0032225//regulation of synaptic transmission, dopaminergic;GO:0071385//cellular response to glucocorticoid stimulus;GO:0001838//embryonic epithelial tube formation;GO:0006366//transcription from RNA polymerase II promoter;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0048483//autonomic nervous system development;GO:0032768;GO:0007422//peripheral nervous system development;GO:0006950//response to stress;GO:0043066//negative regulation of apoptotic process;GO:0030030//cell projection organization;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0045995//regulation of embryonic development;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0008406//gonad development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0007420//brain development;GO:0051094//positive regulation of developmental process;GO:0001667//ameboidal-type cell migration;GO:0014821;GO:0003156//regulation of organ formation;GO:0043488//regulation of mRNA stability;GO:0043010//camera-type eye development;GO:0032225//regulation of synaptic transmission, dopaminergic;GO:0071385//cellular response to glucocorticoid stimulus;GO:0001838//embryonic epithelial tube formation;GO:0006366//transcription from RNA polymerase II promoter;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0048483//autonomic nervous system development;GO:0032768;GO:0007422//peripheral nervous system development;GO:0006950//response to stress;GO:0043066//negative regulation of apoptotic process;GO:0030030//cell projection organization;GO:0014046;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0048754//branching morphogenesis of an epithelial tube;GO:0051094//positive regulation of developmental process;GO:0001667//ameboidal-type cell migration;GO:0014821;GO:0006935//chemotaxis;GO:0003156//regulation of organ formation;GO:0007626//locomotory behavior;GO:0043488//regulation of mRNA stability;GO:0032225//regulation of synaptic transmission, dopaminergic;GO:0001838//embryonic epithelial tube formation;GO:0006366//transcription from RNA polymerase II promoter;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0048483//autonomic nervous system development;GO:0032768;GO:0007422//peripheral nervous system development;GO:0006950//response to stress;GO:0043066//negative regulation of apoptotic process;GO:0030030//cell projection organization;GO:0014046;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0045995//regulation of embryonic development;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0008406//gonad development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0007420//brain development;GO:0051094//positive regulation of developmental process;GO:0001667//ameboidal-type cell migration;GO:0014821;GO:0006935//chemotaxis;GO:0003156//regulation of organ formation;GO:0007626//locomotory behavior;GO:0043488//regulation of mRNA stability;GO:0043010//camera-type eye development;GO:0032225//regulation of synaptic transmission, dopaminergic;GO:0071385//cellular response to glucocorticoid stimulus;GO:0001838//embryonic epithelial tube formation;GO:0006366//transcription from RNA polymerase II promoter;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0048483//autonomic nervous system development;GO:0032768;GO:0007422//peripheral nervous system development;GO:0006950//response to stress;GO:0043066//negative regulation of apoptotic process;GO:0030030//cell projection organization" gi|672349283|ref|NP_001288262.1|/2.32934e-105/glial cell line-derived neurotrophic factor isoform 3 [Mus musculus] 50786 4313 0.066666667 0.093333333 0.485426827 Up 0.120736019 Hs6st2 heparan sulfate 6-O-sulfotransferase 2 K08102|1|0.0|845|rno:302489|heparan sulfate 6-O-sulfotransferase HS6ST2 [EC:2.8.2.-] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0003824//catalytic activity;GO:0003824//catalytic activity - "gi|28502977|gb|AAH47151.1|/0/Hs6st2 protein, partial [Mus musculus]" 240641 5563 0.103333333 0.073333333 -0.494764692 Down 0.120736019 Kif20b kinesin family member 20B K10402|1|0.0|3323|mmu:240641|kinesin family member 20 GO:0031981//nuclear lumen;GO:0005815//microtubule organizing center GO:0032550;GO:0019904//protein domain specific binding;GO:0003774//motor activity GO:0006928//movement of cell or subcellular component;GO:0009154//purine ribonucleotide catabolic process;GO:0000087//mitotic M phase gi|133505571|ref|NP_898867.1|/0/kinesin-like protein KIF20B [Mus musculus] 20750 1423 0.073333333 0.103333333 0.494764692 Up 0.120736019 Spp1 secreted phosphoprotein 1 K06250|1|8e-134|479|mmu:20750|secreted phosphoprotein 1 GO:0031982//vesicle;GO:0044421;GO:0044444//cytoplasmic part;GO:0031982//vesicle;GO:0044421;GO:0044444//cytoplasmic part;GO:0031982//vesicle;GO:0044421;GO:0044444//cytoplasmic part;GO:0031982//vesicle;GO:0044421;GO:0044444//cytoplasmic part;GO:0031982//vesicle;GO:0044421;GO:0044444//cytoplasmic part GO:0005102//receptor binding;GO:0005102//receptor binding;GO:0005102//receptor binding;GO:0005102//receptor binding;GO:0005102//receptor binding GO:0009888//tissue development;GO:0032846;GO:0048671//negative regulation of collateral sprouting;GO:0006915//apoptotic process;GO:0001503//ossification;GO:0010810//regulation of cell-substrate adhesion;GO:0014070//response to organic cyclic compound;GO:0009725//response to hormone;GO:0006952//defense response;GO:0030595//leukocyte chemotaxis;GO:0009888//tissue development;GO:0032846;GO:0048671//negative regulation of collateral sprouting;GO:0006915//apoptotic process;GO:0001503//ossification;GO:0010810//regulation of cell-substrate adhesion;GO:0014070//response to organic cyclic compound;GO:0009725//response to hormone;GO:0006952//defense response;GO:0030595//leukocyte chemotaxis;GO:0009888//tissue development;GO:0032846;GO:0048671//negative regulation of collateral sprouting;GO:0006915//apoptotic process;GO:0001503//ossification;GO:0010810//regulation of cell-substrate adhesion;GO:0014070//response to organic cyclic compound;GO:0009725//response to hormone;GO:0006952//defense response;GO:0030595//leukocyte chemotaxis;GO:0009888//tissue development;GO:0032846;GO:0048671//negative regulation of collateral sprouting;GO:0006915//apoptotic process;GO:0001503//ossification;GO:0010810//regulation of cell-substrate adhesion;GO:0014070//response to organic cyclic compound;GO:0009725//response to hormone;GO:0006952//defense response;GO:0030595//leukocyte chemotaxis;GO:0009888//tissue development;GO:0032846;GO:0048671//negative regulation of collateral sprouting;GO:0006915//apoptotic process;GO:0001503//ossification;GO:0010810//regulation of cell-substrate adhesion;GO:0014070//response to organic cyclic compound;GO:0009725//response to hormone;GO:0006952//defense response;GO:0030595//leukocyte chemotaxis gi|323668333|ref|NP_001191130.1|/2.18858e-139/osteopontin isoform 1 [Mus musculus] 75689 753 10.7 10.89 0.025393157 Up 0.120736019 Higd1b "HIG1 domain family, member 1B" - GO:0031224//intrinsic component of membrane - - gi|18252786|ref|NP_543122.1|/3.63833e-49/HIG1 domain family member 1B [Mus musculus] 76218 1585 0.066666667 0.093333333 0.485426827 Up 0.120736019 6430710C18Rik RIKEN cDNA 6430710C18 gene "K10408|1|2e-06|55.5|mze:101486364|dynein heavy chain, axonemal" - - - "gi|148695168|gb|EDL27115.1|/1.70548e-10/mCG21769, isoform CRA_a [Mus musculus]" 241633 5529 0.103333333 0.073333333 -0.494764692 Down 0.120736019 Atp8b4 "ATPase, class I, type 8B, member 4" K01530|1|0.0|2255|mmu:241633|phospholipid-translocating ATPase [EC:3.6.3.1] GO:0031224//intrinsic component of membrane GO:0005548//phospholipid transporter activity;GO:0046872//metal ion binding;GO:0008324//cation transmembrane transporter activity;GO:0032550 - gi|157671921|ref|NP_001074413.2|/0/probable phospholipid-transporting ATPase IM [Mus musculus] 58887 3161.7 10.64333333 10.83333333 0.025527165 Up 0.120736019 Repin1 replication initiator 1 K09228|1|1e-111|407|pss:106731266|KRAB domain-containing zinc finger protein GO:0005840//ribosome;GO:0005635//nuclear envelope;GO:0005840//ribosome;GO:0005635//nuclear envelope;GO:0005840//ribosome;GO:0005635//nuclear envelope;GO:0005840//ribosome;GO:0005635//nuclear envelope GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0032368//regulation of lipid transport;GO:0006259//DNA metabolic process;GO:0046324//regulation of glucose import;GO:0032368//regulation of lipid transport;GO:0006259//DNA metabolic process;GO:0046324//regulation of glucose import;GO:0032368//regulation of lipid transport;GO:0006259//DNA metabolic process;GO:0046324//regulation of glucose import;GO:0032368//regulation of lipid transport;GO:0006259//DNA metabolic process;GO:0046324//regulation of glucose import gi|347658946|ref|NP_001073373.2|/0/replication initiator 1 isoform d [Mus musculus] 83397 6262 8.273333333 8.08 -0.034113417 Down 0.120736019 Akap12 A kinase (PRKA) anchor protein (gravin) 12 K16528|1|0.0|2570|mmu:83397|A-kinase anchor protein 12 GO:0016020//membrane;GO:0043232 "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019899//enzyme binding;GO:0032947//protein complex scaffold" GO:0006886//intracellular protein transport;GO:0006171//cAMP biosynthetic process;GO:0010737//protein kinase A signaling gi|13626040|ref|NP_112462.1|/0/A-kinase anchor protein 12 [Mus musculus] 76937 585 0.066666667 0.093333333 0.485426827 Up 0.120736019 2810429I04Rik RIKEN cDNA 2810429I04 gene - - - - - 13897 2073 0.093333333 0.066666667 -0.485426827 Down 0.120736019 Ces1e carboxylesterase 1E K01044|1|0.0|1071|mmu:13897|carboxylesterase 1 [EC:3.1.1.1] GO:0044432 GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity - "gi|148679150|gb|EDL11097.1|/0/esterase 22, partial [Mus musculus]" 22385 6446 9.453333333 9.643333333 0.028708791 Up 0.120736019 Baz1b "bromodomain adjacent to zinc finger domain, 1B" K11658|1|0.0|2409|mmu:22385|bromodomain adjacent to zinc finger domain protein 1B "GO:0000775//chromosome, centromeric region;GO:0070603//SWI/SNF superfamily-type complex;GO:0005657//replication fork" GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0032550;GO:0030546//receptor activator activity;GO:0004713//protein tyrosine kinase activity;GO:0008134//transcription factor binding "GO:0006351//transcription, DNA-templated;GO:0006337//nucleosome disassembly;GO:0006468//protein phosphorylation;GO:0006338//chromatin remodeling;GO:0009887//organ morphogenesis;GO:0006281//DNA repair" gi|170295818|ref|NP_035844.2|/0/tyrosine-protein kinase BAZ1B [Mus musculus] 74192 1271 51.94333333 51.18333333 -0.021264492 Down 0.120726616 Arpc5l "actin related protein 2/3 complex, subunit 5-like" "K05754|1|6e-75|283|pps:100991419|actin related protein 2/3 complex, subunit 5" GO:0043232 GO:0008092//cytoskeletal protein binding GO:0008064//regulation of actin polymerization or depolymerization gi|694937047|ref|XP_520252.3|/4.66708e-74/PREDICTED: actin-related protein 2/3 complex subunit 5-like protein [Pan troglodytes] 14688 3134.36 49.61333333 48.86 -0.022074026 Down 0.120689007 Gnb1 "guanine nucleotide binding protein (G protein), beta 1" K04536|1|0.0|671|myd:102764577|guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 GO:0001750//photoreceptor outer segment;GO:0043005//neuron projection;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0001750//photoreceptor outer segment;GO:0043005//neuron projection;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0001750//photoreceptor outer segment;GO:0043005//neuron projection;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane GO:0017111//nucleoside-triphosphatase activity;GO:0031701//angiotensin receptor binding;GO:0019899//enzyme binding;GO:0017111//nucleoside-triphosphatase activity;GO:0031701//angiotensin receptor binding;GO:0019899//enzyme binding;GO:0017111//nucleoside-triphosphatase activity;GO:0031701//angiotensin receptor binding;GO:0019899//enzyme binding GO:0015980//energy derivation by oxidation of organic compounds;GO:0007599//hemostasis;GO:0007267//cell-cell signaling;GO:0043010//camera-type eye development;GO:0071407//cellular response to organic cyclic compound;GO:0033762//response to glucagon;GO:0034695//response to prostaglandin E;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007264//small GTPase mediated signal transduction;GO:0001666//response to hypoxia;GO:0009154//purine ribonucleotide catabolic process;GO:0010658;GO:0001775//cell activation;GO:0007606//sensory perception of chemical stimulus;GO:0015980//energy derivation by oxidation of organic compounds;GO:0007599//hemostasis;GO:0007267//cell-cell signaling;GO:0043010//camera-type eye development;GO:0071407//cellular response to organic cyclic compound;GO:0033762//response to glucagon;GO:0034695//response to prostaglandin E;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007264//small GTPase mediated signal transduction;GO:0001666//response to hypoxia;GO:0009154//purine ribonucleotide catabolic process;GO:0010658;GO:0001775//cell activation;GO:0007606//sensory perception of chemical stimulus;GO:0015980//energy derivation by oxidation of organic compounds;GO:0007599//hemostasis;GO:0007267//cell-cell signaling;GO:0043010//camera-type eye development;GO:0071407//cellular response to organic cyclic compound;GO:0033762//response to glucagon;GO:0034695//response to prostaglandin E;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007264//small GTPase mediated signal transduction;GO:0001666//response to hypoxia;GO:0009154//purine ribonucleotide catabolic process;GO:0010658;GO:0001775//cell activation;GO:0007606//sensory perception of chemical stimulus "gi|148683063|gb|EDL15010.1|/0/guanine nucleotide binding protein, beta 1, isoform CRA_a, partial [Mus musculus]" 68087 1714 43.47333333 44.21 0.024242015 Up 0.120604385 Dcakd dephospho-CoA kinase domain containing K00859|1|5e-38|161|cbr:CBG10005|dephospho-CoA kinase [EC:2.7.1.24];K02318|3|1e-28|130|obi:106882755|phosphopantetheine adenylyltransferase / dephospho-CoA kinase [EC:2.7.7.3 2.7.1.24] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0016301//kinase activity GO:0009108//coenzyme biosynthetic process;GO:0006796//phosphate-containing compound metabolic process gi|880883747|ref|XP_012968925.1|/2.91171e-128/PREDICTED: dephospho-CoA kinase domain-containing protein isoform X1 [Mesocricetus auratus] 53599 2830 49.54 48.82 -0.021121573 Down 0.120510361 Cd164 CD164 antigen K06546|1|4e-73|279|mmu:53599|CD164 antigen GO:0000323//lytic vacuole;GO:0016020//membrane - GO:0016337//single organismal cell-cell adhesion gi|8393787|ref|NP_058594.1|/3.20489e-72/sialomucin core protein 24 precursor [Mus musculus] 53895 1207 61.26666667 61.98333333 0.016777981 Up 0.120510361 Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit "K01358|1|1e-134|481|mmu:53895|ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]" GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004175//endopeptidase activity;GO:0005515//protein binding GO:0051259//protein oligomerization;GO:0019538//protein metabolic process "gi|8393156|ref|NP_059089.1|/1.08664e-133/ATP-dependent Clp protease proteolytic subunit, mitochondrial precursor [Mus musculus]" 76960 2952 0.07 0.096666667 0.465663572 Up 0.120444545 Bcas1 breast carcinoma amplified sequence 1 K07436|1|1e-25|121|tgu:100226727|vitamin D3 24-hydroxylase [EC:1.14.15.16];K13172|2|1e-05|55.5|lcm:102356501|serine/arginine repetitive matrix protein 2 - - - gi|568918829|ref|XP_006500445.1|/0/PREDICTED: breast carcinoma-amplified sequence 1 homolog isoform X2 [Mus musculus] 403175 3459 0.086666667 0.12 0.469485283 Up 0.120444545 Tigd4 tigger transposable element derived 4 K11496|1|1e-49|201|oaa:100077513|centromere protein B;K19326|4|2e-42|177|lcm:102349340|nesprin-1 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding - gi|46402305|ref|NP_997161.1|/0/tigger transposable element-derived protein 4 [Mus musculus] 14675 3383 0.086666667 0.12 0.469485283 Up 0.120444545 Gna14 "guanine nucleotide binding protein, alpha 14" K04636|1|0.0|707|mmu:14675|guanine nucleotide-binding protein subunit alpha-14 GO:0031234//extrinsic component of cytoplasmic side of plasma membrane GO:0017111//nucleoside-triphosphatase activity;GO:0043169//cation binding;GO:0032550;GO:0060089;GO:0032403//protein complex binding;GO:0005102//receptor binding;GO:0017076//purine nucleotide binding "GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger" gi|160298199|ref|NP_032163.3|/0/guanine nucleotide-binding protein subunit alpha-14 [Mus musculus] 100504377 3997 0.086666667 0.12 0.469485283 Up 0.120444545 Gm20199 "predicted gene, 20199" - - - - gi|74187902|dbj|BAE37095.1|/8.17162e-32/unnamed protein product [Mus musculus] 207839 5711.49 0.086666667 0.12 0.469485283 Up 0.120444545 Galnt6 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 K00710|1|0.0|1229|mmu:207839|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0008376//acetylgalactosaminyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity GO:0006493//protein O-linked glycosylation;GO:0006493//protein O-linked glycosylation;GO:0006493//protein O-linked glycosylation gi|240120031|ref|NP_766039.2|/0/polypeptide N-acetylgalactosaminyltransferase 6 [Mus musculus] 100127433 5442 0.11 0.08 -0.459431619 Down 0.120444545 Gm11532 predicted gene 11532 K09196|1|0.0|693|mmu:83395|transcription factor Sp6 - - - - 21685 4228.65 48.69666667 49.40666667 0.020882703 Up 0.120416338 Tef thyrotroph embryonic factor K09058|1|3e-121|439|myb:102259516|thyrotrophic embryonic factor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0043566//structure-specific DNA binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0043566//structure-specific DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter gi|8394435|ref|NP_059072.1|/1.84598e-122/thyrotroph embryonic factor isoform 1 [Mus musculus] 435766 3042 43.16333333 42.45333333 -0.023928448 Down 0.120416338 Tnni3k TNNI3 interacting kinase K17535|1|0.0|1639|mmu:435766|serine/threonine-protein kinase TNNI3K [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0008092//cytoskeletal protein binding;GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|260166668|ref|NP_796040.3|/0/serine/threonine-protein kinase TNNI3K [Mus musculus] 66340 670 57.70333333 58.40333333 0.017396051 Up 0.120350521 Psenen presenilin enhancer gamma secretase subunit K06170|1|4e-61|236|ptg:102961369|presenilin enhancer 2 - - - - 69634 1257 65.43333333 64.73333333 -0.015516972 Down 0.120350521 Clybl citrate lyase beta like K11390|1|0.0|665|mmu:69634|citrate lyase subunit beta-like protein [EC:4.1.-.-] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0016833//oxo-acid-lyase activity;GO:0043169//cation binding GO:0044237//cellular metabolic process "gi|256220113|ref|NP_083832.2|/0/citrate lyase subunit beta-like protein, mitochondrial precursor [Mus musculus]" 225994 1637 2.933333333 2.83 -0.05173897 Down 0.120341119 Nmrk1 nicotinamide riboside kinase 1 K10524|1|1e-111|406|mmu:225994|nicotinamide/nicotinate riboside kinase [EC:2.7.1.22 2.7.1.173] - GO:0043169//cation binding;GO:0032550;GO:0016301//kinase activity GO:0019359//nicotinamide nucleotide biosynthetic process gi|21703978|ref|NP_663472.1|/8.87816e-111/nicotinamide riboside kinase 1 [Mus musculus] 218138 1510 2.833333333 2.933333333 0.050040682 Up 0.120341119 Gmds "GDP-mannose 4, 6-dehydratase" "K01711|1|0.0|760|mmu:218138|GDPmannose 4,6-dehydratase [EC:4.2.1.47]" GO:0044424 GO:0043168//anion binding;GO:0036094//small molecule binding;GO:0048037//cofactor binding;GO:0016836//hydro-lyase activity GO:0042350//GDP-L-fucose biosynthetic process;GO:0007166//cell surface receptor signaling pathway "gi|22122523|ref|NP_666153.1|/0/GDP-mannose 4,6 dehydratase [Mus musculus]" 67448 6963 2.963333333 2.863333333 -0.049525288 Down 0.120341119 Plxdc2 plexin domain containing 2 - GO:0031224//intrinsic component of membrane GO:0005488//binding - gi|31543855|ref|NP_080438.2|/0/plexin domain-containing protein 2 precursor [Mus musculus] 68815 2563 3.113333333 3.213333333 0.045610597 Up 0.120341119 Btbd10 BTB (POZ) domain containing 10 K10482|1|0.0|804|mmu:68815|BTB/POZ domain-containing protein 10 GO:0031981//nuclear lumen - - gi|30794234|ref|NP_598461.1|/0/BTB/POZ domain-containing protein 10 [Mus musculus] 78658 5519 2.696666667 2.596666667 -0.054516374 Down 0.120341119 Ncapd3 "non-SMC condensin II complex, subunit D3" K11491|1|0.0|2751|mmu:78658|condensin-2 complex subunit D3 GO:0000794//condensed nuclear chromosome;GO:0005720//nuclear heterochromatin;GO:0001674//female germ cell nucleus GO:0042393//histone binding GO:0000070//mitotic sister chromatid segregation gi|161016797|ref|NP_835214.2|/0/condensin-2 complex subunit D3 [Mus musculus] 56697 3879 3.116666667 3.22 0.047056824 Up 0.120341119 Akap10 A kinase (PRKA) anchor protein 10 K16526|1|0.0|1316|mmu:56697|A-kinase anchor protein 10 - - - "gi|40807354|ref|NP_064305.2|/0/A-kinase anchor protein 10, mitochondrial precursor [Mus musculus]" 100532 3240 3.103333333 3.006666667 -0.045653734 Down 0.120341119 Rell1 RELT-like 1 K05156|1|1e-19|101|cfa:485200|tumor necrosis factor receptor superfamily member 19-like GO:0005856//cytoskeleton;GO:0031224//intrinsic component of membrane - - gi|110625912|ref|NP_666035.2|/8.77315e-130/RELT-like protein 1 precursor [Mus musculus] 12330 4290.35 52.07 52.75666667 0.018901007 Up 0.120247095 Canx calnexin K08054|1|0.0|1038|mmu:12330|calnexin GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0044297//cell body;GO:0031090//organelle membrane;GO:0030529//intracellular ribonucleoprotein complex;GO:0048770;GO:0005783//endoplasmic reticulum;GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0044297//cell body;GO:0031090//organelle membrane;GO:0030529//intracellular ribonucleoprotein complex;GO:0048770;GO:0005783//endoplasmic reticulum;GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0044297//cell body;GO:0031090//organelle membrane;GO:0030529//intracellular ribonucleoprotein complex;GO:0048770;GO:0005783//endoplasmic reticulum GO:0046872//metal ion binding;GO:0035254//glutamate receptor binding;GO:0046872//metal ion binding;GO:0035254//glutamate receptor binding;GO:0046872//metal ion binding;GO:0035254//glutamate receptor binding GO:0006457//protein folding;GO:0044767//single-organism developmental process;GO:0006898//receptor-mediated endocytosis;GO:0006457//protein folding;GO:0044767//single-organism developmental process;GO:0006898//receptor-mediated endocytosis;GO:0006457//protein folding;GO:0044767//single-organism developmental process;GO:0006898//receptor-mediated endocytosis gi|6671664|ref|NP_031623.1|/0/calnexin precursor [Mus musculus] 70230 1092 0.096666667 0.13 0.427421224 Up 0.12022829 3300002P13Rik RIKEN cDNA 3300002P13 gene - - - - - 68283 2173 0.113333333 0.083333333 -0.443606651 Down 0.12022829 9530077C05Rik RIKEN cDNA 9530077C05 gene - - - - - 84112 1571 0.126666667 0.093333333 -0.440572591 Down 0.12022829 Sucnr1 succinate receptor 1 K10042|1|0.0|640|mmu:84112|succinate receptor 1 GO:0031224//intrinsic component of membrane GO:0001608 GO:0035588 gi|254692932|ref|NP_115776.2|/0/succinate receptor 1 [Mus musculus] 53868 1060 0.096666667 0.13 0.427421224 Up 0.12022829 Rab25 "RAB25, member RAS oncogene family" K07906|1|4e-116|420|mmu:53868|Ras-related protein Rab-25 GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0031143//pseudopodium;GO:0016020//membrane GO:0032550 GO:0035556//intracellular signal transduction;GO:0030030//cell projection organization;GO:0045184//establishment of protein localization;GO:0008283//cell proliferation gi|31980838|ref|NP_058595.2|/3.16895e-115/ras-related protein Rab-25 [Mus musculus] 16574 6867 0.126666667 0.093333333 -0.440572591 Down 0.12022829 Kif5c kinesin family member 5C K10396|1|0.0|1712|mmu:16574|kinesin family member 5 GO:0005875//microtubule associated complex;GO:0042995//cell projection GO:0005102//receptor binding GO:0007411//axon guidance gi|26006171|dbj|BAC41428.1|/0/mKIAA0531 protein [Mus musculus] 110350 13972 0.103333333 0.076666667 -0.430634354 Down 0.12022829 Dync2h1 dynein cytoplasmic 2 heavy chain 1 "K10414|1|0.0|8359|mmu:110350|dynein heavy chain 2, cytosolic" GO:0016020//membrane;GO:0072372//primary cilium;GO:0005875//microtubule associated complex;GO:0005930//axoneme GO:0032550;GO:0003774//motor activity GO:0051604//protein maturation;GO:0035108//limb morphogenesis;GO:0009855//determination of bilateral symmetry;GO:0022607//cellular component assembly;GO:0048870//cell motility;GO:0003002//regionalization;GO:0006996//organelle organization;GO:0007420//brain development;GO:0008104//protein localization;GO:0048858//cell projection morphogenesis;GO:0010927;GO:0021515//cell differentiation in spinal cord gi|72534792|ref|NP_084127.2|/0/cytoplasmic dynein 2 heavy chain 1 [Mus musculus] 14260 11632.24 0.1 0.073333333 -0.447458977 Down 0.12022829 Fmn1 formin 1 K10367|1|3e-55|221|mmu:14260|formin 1 - - - gi|550544203|ref|NP_001272388.1|/2.3837e-54/formin-1 isoform 4 [Mus musculus] 100039062 3025 0.08 0.106666667 0.415037499 Up 0.12022829 Gm2027 nuclear assembly factor 1 homolog pseudogene K14763|1|6e-149|531|mmu:234344|H/ACA ribonucleoprotein complex non-core subunit NAF1 GO:0005815//microtubule organizing center;GO:0030529//intracellular ribonucleoprotein complex GO:0003723//RNA binding GO:0042254//ribosome biogenesis;GO:0016070//RNA metabolic process gi|148696755|gb|EDL28702.1|/1.55172e-155/mCG52162 [Mus musculus] 100041576 7912 0.073333333 0.1 0.447458977 Up 0.12022829 Gm3414 predicted gene 3414 - - - - gi|755511408|ref|XP_011239013.1|/0/PREDICTED: ligand-dependent nuclear receptor corepressor-like protein isoform X4 [Mus musculus] 554327 1885 0.103333333 0.076666667 -0.430634354 Down 0.12022829 2610042L04Rik RIKEN cDNA 2610042L04 gene "K03844|1|5e-20|102|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - gi|755546841|ref|XP_011243026.1|/1.10477e-101/PREDICTED: predicted gene 3264 isoform X1 [Mus musculus] 246086 4705 0.113333333 0.083333333 -0.443606651 Down 0.12022829 Onecut3 "one cut domain, family member 3" "K08026|1|5e-81|306|phi:102109738|one cut domain, family member 1, hepatocyte nuclear factor 6" GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity GO:0031016//pancreas development;GO:0006366//transcription from RNA polymerase II promoter gi|40538836|ref|NP_631972.2|/5.54809e-144/one cut domain family member 3 [Mus musculus] 241447 3930 0.273333333 0.236666667 -0.207804885 Down 0.120209485 Cers6 ceramide synthase 6 K04710|1|0.0|725|mmu:241447|ceramide synthetase [EC:2.3.1.24] GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0005635//nuclear envelope GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0016410//N-acyltransferase activity "GO:0006796//phosphate-containing compound metabolic process;GO:0006672//ceramide metabolic process;GO:0006351//transcription, DNA-templated" gi|27370296|ref|NP_766444.1|/0/ceramide synthase 6 [Mus musculus] 59058 3207 0.29 0.25 -0.214124805 Down 0.120209485 Bhlhe22 "basic helix-loop-helix family, member e22" K09086|1|8e-125|451|mmu:59058|class B basic helix-loop-helix protein 4/5 GO:0043231//intracellular membrane-bounded organelle GO:0042802//identical protein binding "GO:0003407//neural retina development;GO:0021537//telencephalon development;GO:0021952//central nervous system projection neuron axonogenesis;GO:0006351//transcription, DNA-templated" gi|170295816|ref|NP_067535.3|/7.1081e-124/class E basic helix-loop-helix protein 22 [Mus musculus] 209707 5382.14 0.323333333 0.28 -0.207595419 Down 0.120209485 Lcorl ligand dependent nuclear receptor corepressor-like K06678|1|3e-12|78.2|mmu:54392|condensin complex subunit 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter gi|537253133|gb|ERE88688.1|/0/ligand-dependent nuclear receptor corepressor-like protein [Cricetulus griseus] 207683 3430 0.326666667 0.283333333 -0.205318908 Down 0.120209485 Igsf11 "immunoglobulin superfamily, member 11" "K06791|1|0.0|729|mmu:207683|immunoglobulin superfamily, member 11" GO:0031224//intrinsic component of membrane - GO:0022610;GO:0040007//growth gi|40254205|ref|NP_733548.2|/0/immunoglobulin superfamily member 11 precursor [Mus musculus] 67261 2033 0.313333333 0.27 -0.214738849 Down 0.120209485 2900005J15Rik RIKEN cDNA 2900005J15 gene - - - - gi|148671135|gb|EDL03082.1|/2.16472e-64/mCG142216 [Mus musculus] 434198 1820 0.27 0.233333333 -0.210566986 Down 0.120209485 B130024G19Rik RIKEN cDNA B130024G19 gene - - - - - 381270 4217 0.276666667 0.24 -0.20511443 Down 0.120209485 4-Mar membrane-associated ring finger (C3HC4) 4 K10659|1|0.0|649|mmu:381270|E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27] GO:0044431//Golgi apparatus part;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity - gi|28972736|dbj|BAC65784.1|/0/mKIAA1399 protein [Mus musculus] 321022 3628.42 46.22 46.9 0.021070663 Up 0.120162473 Cdv3 carnitine deficiency-associated gene expressed in ventricle 3 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|28461294|ref|NP_787027.1|/1.68507e-67/protein CDV3 isoform b [Mus musculus] 59092 2099 40.15666667 39.49333333 -0.024030379 Down 0.119983828 Pcbp4 poly(rC) binding protein 4 K13162|1|0.0|693|rro:104663725|poly(rC)-binding protein 2/3/4 - - - - 70999 3275 8.36 8.176666667 -0.031990114 Down 0.119983828 Naa40 "N(alpha)-acetyltransferase 40, NatD catalytic subunit" - - GO:0016407//acetyltransferase activity - gi|12855273|dbj|BAB30275.1|/1.15568e-125/unnamed protein product [Mus musculus] 52715 2307 7.613333333 7.436666667 -0.033872137 Down 0.119983828 Ccdc43 coiled-coil domain containing 43 - - - - gi|13385406|ref|NP_080194.1|/2.86431e-92/coiled-coil domain-containing protein 43 [Mus musculus] 20729 4463.56 8.97 9.146666667 0.028138091 Up 0.119983828 Spin1 spindlin 1 - - - - - 27355 4274 7.85 7.673333333 -0.032839226 Down 0.119983828 Pald1 "phosphatase domain containing, paladin 1" - GO:0044424 - - gi|187951755|gb|AAI37696.1|/0/X99384 protein [Mus musculus] 66894 4319 8.59 8.413333333 -0.029980627 Down 0.119983828 Wwp2 WW domain containing E3 ubiquitin protein ligase 2 K05630|1|0.0|1683|mmu:66894|atrophin-1 interacting protein 2 (WW domain containing E3 ubiquitin protein ligase 2) [EC:2.3.2.26] - - - gi|13385304|ref|NP_080106.1|/0/NEDD4-like E3 ubiquitin-protein ligase WWP2 [Mus musculus] 66993 1743 49.20666667 48.55333333 -0.019283445 Down 0.119918011 Smarcd3 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3" K11650|1|0.0|832|ocu:100345769|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0090544//BAF-type complex GO:0051427//hormone receptor binding;GO:0003713//transcription coactivator activity GO:0003128//heart field specification;GO:0006366//transcription from RNA polymerase II promoter;GO:0034728//nucleosome organization;GO:0007405//neuroblast proliferation;GO:0003211//cardiac ventricle formation;GO:0006629//lipid metabolic process;GO:0051098//regulation of binding;GO:0016568//chromatin modification gi|77404373|ref|NP_080167.3|/0/SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 [Mus musculus] 68682 3471.99 39.41 40.05666667 0.023480622 Up 0.119918011 Slc44a2 "solute carrier family 44, member 2" "K15377|1|0.0|1287|mmu:68682|solute carrier family 44 (choline transporter-like protein), member 2/4/5" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0060089;GO:0060089 GO:0051234//establishment of localization;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0051234//establishment of localization;GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|312596932|ref|NP_001186115.1|/0/choline transporter-like protein 2 isoform 1 [Mus musculus] 270672 4348 54.83333333 54.18 -0.017292785 Down 0.119918011 Map3k15 mitogen-activated protein kinase kinase kinase 15 K13986|1|0.0|2426|mmu:270672|mitogen-activated protein kinase kinase kinase 15 [EC:2.7.11.25] - GO:0043169//cation binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|282847404|ref|NP_001156557.2|/0/mitogen-activated protein kinase kinase kinase 15 [Mus musculus] 107260 1677 47.79 47.15333333 -0.019349007 Down 0.119842792 Otub1 "OTU domain, ubiquitin aldehyde binding 1" K09602|1|4e-146|520|hgl:101706271|ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12] GO:0044424 GO:0008238//exopeptidase activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0019783//ubiquitin-like protein-specific protease activity;GO:0032182//ubiquitin-like protein binding GO:0006302//double-strand break repair;GO:0033183;GO:0016579//protein deubiquitination gi|635012684|ref|XP_007992591.1|/3.80748e-149/PREDICTED: ubiquitin thioesterase OTUB1 [Chlorocebus sabaeus] 66928 769 43.04666667 43.68 0.02107133 Up 0.119786378 Tmem261 transmembrane protein 261 - GO:0031224//intrinsic component of membrane - - gi|13385326|ref|NP_080125.1|/8.12832e-36/transmembrane protein 261 [Mus musculus] 22377 1336.75 39.26666667 39.9 0.023083613 Up 0.119786378 Wbp1 WW domain binding protein 1 - - GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding - gi|145046224|ref|NP_001077392.1|/4.16194e-96/WW domain-binding protein 1 isoform 3 [Mus musculus] 16162 1900 0.546666667 0.5 -0.128733314 Down 0.119758171 Il12rb2 "interleukin 12 receptor, beta 2" K05064|1|0.0|1565|rno:171334|interleukin 12 receptor beta-2 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane GO:0019900//kinase binding;GO:0019900//kinase binding;GO:0019955//cytokine binding;GO:0004896//cytokine receptor activity GO:0002237//response to molecule of bacterial origin;GO:0006468//protein phosphorylation;GO:0001819//positive regulation of cytokine production;GO:0006468//protein phosphorylation;GO:0001819//positive regulation of cytokine production;GO:0019221//cytokine-mediated signaling pathway;GO:0002237//response to molecule of bacterial origin;GO:0008283//cell proliferation gi|6680401|ref|NP_032380.1|/0/interleukin-12 receptor subunit beta-2 isoform 1 precursor [Mus musculus] 21936 817 0.536666667 0.49 -0.131244533 Down 0.119758171 Tnfrsf18 "tumor necrosis factor receptor superfamily, member 18" K05154|1|6e-142|505|mmu:21936|tumor necrosis factor receptor superfamily member 18 GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0009986//cell surface - GO:0012501//programmed cell death;GO:0012501//programmed cell death "gi|148683124|gb|EDL15071.1|/0/tumor necrosis factor receptor superfamily, member 18, isoform CRA_c, partial [Mus musculus]" 319508 3625 0.556666667 0.51 -0.12631645 Down 0.119758171 Syt15 synaptotagmin XV K19914|1|0.0|831|mmu:319508|synaptotagmin-15 GO:0030136//clathrin-coated vesicle;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|31542579|ref|NP_852682.1|/0/synaptotagmin-15 isoform a [Mus musculus] 16784 2997.72 41.42333333 40.80666667 -0.021638784 Down 0.119758171 Lamp2 lysosomal-associated membrane protein 2 K06528|1|0.0|739|mmu:16784|lysosomal-associated membrane protein 1/2 GO:0030667//secretory granule membrane;GO:0005770//late endosome;GO:0030666//endocytic vesicle membrane;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0030667//secretory granule membrane;GO:0005770//late endosome;GO:0030666//endocytic vesicle membrane;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0030667//secretory granule membrane;GO:0005770//late endosome;GO:0030666//endocytic vesicle membrane;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane - - gi|594190997|ref|NP_001277414.1|/0/lysosome-associated membrane glycoprotein 2 isoform 3 precursor [Mus musculus] 237759 5665 0.533333333 0.583333333 0.129283017 Up 0.119758171 Col23a1 "collagen, type XXIII, alpha 1" "K16617|1|2e-31|142|lcm:102359040|collagen, type XIII, alpha" GO:0044464;GO:0005576//extracellular region - - "gi|119574218|gb|EAW53833.1|/1.24905e-128/collagen, type XXIII, alpha 1, isoform CRA_a [Homo sapiens]" 27376 4000 4.11 3.986666667 -0.04395541 Down 0.119645342 Slc25a10 "solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10" "K13577|1|2e-160|570|mmu:27376|solute carrier family 25 (mitochondrial dicarboxylate transporter), member 10" GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0019866//organelle inner membrane;GO:0005740//mitochondrial envelope GO:0015103//inorganic anion transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0015556//C4-dicarboxylate transmembrane transporter activity GO:0015743//malate transport;GO:0044763;GO:0015744//succinate transport;GO:0006817//phosphate ion transport gi|254826790|ref|NP_038798.2|/1.34423e-159/mitochondrial dicarboxylate carrier [Mus musculus] 16543 3435 4.356666667 4.48 0.040273997 Up 0.119645342 Mdfic MyoD family inhibitor domain containing - GO:0031981//nuclear lumen GO:0008134//transcription factor binding "GO:0006351//transcription, DNA-templated;GO:0016055//Wnt signaling pathway;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006606//protein import into nucleus;GO:0000187//activation of MAPK activity" gi|74192518|dbj|BAE43047.1|/3.5251e-161/unnamed protein product [Mus musculus] 320727 5359 4.186666667 4.063333333 -0.043138338 Down 0.119645342 Ipo8 importin 8 K18755|1|0.0|1894|mmu:320727|importin-8 GO:0005635//nuclear envelope GO:0022892//substrate-specific transporter activity GO:0015031//protein transport gi|124487445|ref|NP_001074582.1|/0/importin-8 [Mus musculus] 66528 956 4.533333333 4.41 -0.03979359 Down 0.119645342 Smim5 small integral membrane protein 5 - GO:0031224//intrinsic component of membrane - - "gi|148702585|gb|EDL34532.1|/1.45392e-44/RIKEN cDNA 2210020M01, isoform CRA_a, partial [Mus musculus]" 102058 7427 4.236666667 4.353333333 0.039190867 Up 0.119645342 Exoc8 exocyst complex component 8 K19986|1|0.0|1253|mmu:102058|exocyst complex component 8 - - - - 99696 4915 3.686666667 3.803333333 0.044947406 Up 0.119645342 Ankrd50 ankyrin repeat domain 50 - - - - gi|37360632|dbj|BAC98294.1|/4.89541e-167/mKIAA1223 splice variant 1 [Mus musculus] 71602 4944 4.753333333 4.873333333 0.03596933 Up 0.119645342 Myo1e myosin IE K10356|1|0.0|2128|mmu:71602|myosin I GO:0032991//macromolecular complex;GO:0070161;GO:0015629//actin cytoskeleton;GO:0030139//endocytic vesicle GO:0032550;GO:0005543//phospholipid binding;GO:0003779//actin binding;GO:0016887//ATPase activity GO:0030198//extracellular matrix organization;GO:0009791//post-embryonic development;GO:0048534//hematopoietic or lymphoid organ development;GO:0043009//chordate embryonic development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016192//vesicle-mediated transport;GO:0097205//renal filtration;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0008152//metabolic process gi|68299824|ref|NP_851417.2|/0/unconventional myosin-Ie [Mus musculus] 69774 1687 3.863333333 3.983333333 0.044130052 Up 0.119645342 Ms4a6b "membrane-spanning 4-domains, subfamily A, member 6B" "K08090|1|1e-15|87.4|tup:102468334|membrane-spanning 4-domains, subfamily A, member 2" GO:0031224//intrinsic component of membrane - - gi|31982630|ref|NP_081485.2|/6.58828e-133/membrane-spanning 4-domains subfamily A member 6B [Mus musculus] 18117 4933 4.31 4.193333333 -0.039590353 Down 0.119645342 Emc8 ER membrane protein complex subunit 8 K06697|1|2e-16|92.0|oaa:100073774|proteasome activator subunit 2 (PA28 beta) GO:0030176//integral component of endoplasmic reticulum membrane - - gi|6754870|ref|NP_035056.1|/2.02216e-120/ER membrane protein complex subunit 8 [Mus musculus] 234723 1796 3.903333333 3.786666667 -0.043778241 Down 0.119645342 Txnl4b thioredoxin-like 4B "K12859|1|3e-24|115|mze:101486010|U5 snRNP protein, DIM1 family" GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex - GO:0008283//cell proliferation;GO:0006396//RNA processing;GO:0000087//mitotic M phase gi|160333183|ref|NP_783577.2|/7.73647e-79/thioredoxin-like protein 4B [Mus musculus] 328133 5247 4.673333333 4.55 -0.038585398 Down 0.119645342 Slc39a9 "solute carrier family 39 (zinc transporter), member 9" "K14715|1|6e-134|482|mmu:328133|solute carrier family 39 (zinc transporter), member 9" GO:0031224//intrinsic component of membrane GO:0008324//cation transmembrane transporter activity GO:0000041//transition metal ion transport;GO:0044763 gi|254939687|ref|NP_080520.2|/4.95409e-133/zinc transporter ZIP9 [Mus musculus] 237459 3643 4.353333333 4.47 0.03815434 Up 0.119645342 Cdk17 cyclin-dependent kinase 17 K15595|1|0.0|1055|oas:101122426|cyclin-dependent kinase 17 [EC:2.7.11.22] - GO:0004674//protein serine/threonine kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|568967519|ref|XP_006513689.1|/0/PREDICTED: cyclin-dependent kinase 17 isoform X3 [Mus musculus] 218914 6371 3.87 3.753333333 -0.044161145 Down 0.119645342 Wapl WAPL cohesin release factor K10615|1|5e-26|124|aqu:105315497|E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26] GO:0000794//condensed nuclear chromosome;GO:0000794//condensed nuclear chromosome - GO:0006260//DNA replication;GO:0035561//regulation of chromatin binding;GO:0007063//regulation of sister chromatid cohesion;GO:0000087//mitotic M phase;GO:0034502//protein localization to chromosome;GO:0042221//response to chemical;GO:0006260//DNA replication;GO:0035561//regulation of chromatin binding;GO:0007063//regulation of sister chromatid cohesion;GO:0000087//mitotic M phase;GO:0034502//protein localization to chromosome;GO:0042221//response to chemical gi|37359874|dbj|BAC97915.1|/0/mKIAA0261 protein [Mus musculus] 104445 2542 39.35333333 39.95 0.021709662 Up 0.119626537 Cdc42ep1 CDC42 effector protein (Rho GTPase binding) 1 - - - - - 101056408 1697 39.59 40.18666667 0.021580849 Up 0.119626537 Gm15816 predicted gene 15816 K10380|1|3e-34|108|ecb:100055459|ankyrin GO:0097060//synaptic membrane;GO:0031672//A band;GO:0032589//neuron projection membrane;GO:0031674//I band;GO:0005856//cytoskeleton;GO:0005783//endoplasmic reticulum "GO:0030674//protein binding, bridging;GO:0008092//cytoskeletal protein binding;GO:0019899//enzyme binding" GO:0016482//cytosolic transport;GO:0006778//porphyrin-containing compound metabolic process;GO:0006612//protein targeting to membrane;GO:0007154//cell communication;GO:0006996//organelle organization;GO:0006812//cation transport;GO:0030218//erythrocyte differentiation "gi|148700924|gb|EDL32871.1|/2.4187e-143/mCG146299, partial [Mus musculus]" 83767 2572 0.27 0.31 0.199308808 Up 0.119532513 Wasf1 "WAS protein family, member 1" "K05753|1|1e-173|613|mmu:83767|WAS protein family, member 1" GO:0005856//cytoskeleton;GO:0031966//mitochondrial membrane;GO:0031252//cell leading edge GO:0008092//cytoskeletal protein binding GO:0048858//cell projection morphogenesis;GO:0008154//actin polymerization or depolymerization;GO:0065003 gi|16877274|gb|AAH16896.1|/8.37866e-173/WASP family 1 [Mus musculus] 240034 4209 0.283333333 0.246666667 -0.199937571 Down 0.119532513 Zfp760 zinc finger protein 760 K09228|1|0.0|1465|mmu:240034|KRAB domain-containing zinc finger protein - - - gi|238550167|ref|NP_001008501.2|/0/zinc finger protein 760 [Mus musculus] 71106 3387 0.25 0.286666667 0.197446064 Up 0.119532513 4933413J09Rik RIKEN cDNA 4933413J09 gene - - - - gi|295916792|gb|ADG59723.1|/9.34513e-90/germ cell specific protein [Mus musculus] 76421 3096 0.253333333 0.29 0.195015982 Up 0.119532513 1700028K03Rik RIKEN cDNA 1700028K03 gene - - - - gi|33286440|ref|NP_877422.1|/2.4424e-94/uncharacterized protein C1orf146 homolog isoform 1 [Mus musculus] 233060 2193 0.31 0.27 -0.199308808 Down 0.119532513 Zfp382 zinc finger protein 382 K09228|1|0.0|1189|mmu:233060|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|124486594|ref|NP_001074476.1|/0/zinc finger protein 382 [Mus musculus] 21452 2059.75 51.08 50.49333333 -0.016665605 Down 0.119504306 Tcn2 transcobalamin 2 K14619|1|0.0|813|mmu:21452|transcobalamin-2 - - - gi|7657639|ref|NP_056564.1|/0/transcobalamin-2 precursor [Mus musculus] 226971 3195.82 49.10333333 48.51 -0.017538784 Down 0.119504306 Plekhb2 "pleckstrin homology domain containing, family B (evectins) member 2" K10591|1|3e-06|57.0|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] GO:0043231//intracellular membrane-bounded organelle GO:0008289//lipid binding - "gi|149046403|gb|EDL99296.1|/3.38089e-88/pleckstrin homology domain containing, family B (evectins) member 2 (predicted), isoform CRA_a [Rattus norvegicus]" 68572 734 55.75 56.33333333 0.015017036 Up 0.119447892 Ict1 immature colon carcinoma transcript 1 K15033|1|2e-84|313|mmu:68572|peptidyl-tRNA hydrolase ICT1 [EC:3.1.1.29] GO:0043231//intracellular membrane-bounded organelle;GO:0000315//organellar large ribosomal subunit GO:0003747//translation release factor activity;GO:0052689//carboxylic ester hydrolase activity GO:0006415//translational termination "gi|19387848|ref|NP_081005.1|/1.63617e-83/peptidyl-tRNA hydrolase ICT1, mitochondrial [Mus musculus]" 74287 3251 48.94666667 48.36333333 -0.017296931 Down 0.119447892 Kcmf1 potassium channel modulatory factor 1 K15697|1|3e-12|77.0|dre:414843|RING finger protein 114 [EC:2.3.2.27] - GO:0046872//metal ion binding GO:0032446//protein modification by small protein conjugation gi|189491869|ref|NP_001121664.1|/1.26056e-160/E3 ubiquitin-protein ligase KCMF1 [Rattus norvegicus] 22110 2696 41.34 41.90666667 0.019641383 Up 0.119363271 Tspyl1 "testis-specific protein, Y-encoded-like 1" K11284|1|0.0|721|mmu:22110|TSPY-like 1 GO:0031981//nuclear lumen - GO:0034728//nucleosome organization gi|6678445|ref|NP_033459.1|/0/testis-specific Y-encoded-like protein 1 [Mus musculus] 74383 3944.02 53.10666667 53.68 0.015491693 Up 0.119363271 Ubap2l ubiquitin-associated protein 2-like - - GO:0022892//substrate-specific transporter activity;GO:0022892//substrate-specific transporter activity;GO:0022892//substrate-specific transporter activity GO:0035036//sperm-egg recognition;GO:0035036//sperm-egg recognition;GO:0035036//sperm-egg recognition;GO:0035036//sperm-egg recognition;GO:0035036//sperm-egg recognition;GO:0035036//sperm-egg recognition;GO:0035036//sperm-egg recognition;GO:0035036//sperm-egg recognition gi|33239421|ref|NP_082751.1|/0/ubiquitin-associated protein 2-like isoform 1 [Mus musculus] 229593 2723.61 7.78 7.946666667 0.030579675 Up 0.119335063 Golph3l golgi phosphoprotein 3-like K15620|1|4e-130|468|rno:310669|golgi phosphoprotein 3 GO:0000139//Golgi membrane;GO:0000139//Golgi membrane;GO:0000139//Golgi membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - gi|295054280|ref|NP_001171140.1|/1.60086e-150/Golgi phosphoprotein 3-like isoform 2 [Mus musculus] 21915 927.92 10.08333333 9.91 -0.025015679 Down 0.119335063 Dtymk deoxythymidylate kinase K00943|1|5e-38|159|mmu:21915|dTMP kinase [EC:2.7.4.9] GO:0005740//mitochondrial envelope;GO:0005740//mitochondrial envelope "GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0032550;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0070848//response to growth factor;GO:0009212//pyrimidine deoxyribonucleoside triphosphate biosynthetic process;GO:0009197;GO:0048545//response to steroid hormone;GO:0010038//response to metal ion;GO:0042692//muscle cell differentiation;GO:0009123;GO:0009117//nucleotide metabolic process;GO:0009197;GO:0009117//nucleotide metabolic process;GO:0070848//response to growth factor;GO:0009212//pyrimidine deoxyribonucleoside triphosphate biosynthetic process gi|1836042|gb|AAB46838.1|/4.0109e-37/thymidylate kinase [Mus sp.] 70470 4532.44 9.106666667 9.276666667 0.026683425 Up 0.119335063 Rprd1b regulation of nuclear pre-mRNA domain containing 1B K15559|1|6e-158|561|pale:102892704|regulator of Ty1 transposition protein 103 - - - - 71715 3246.93 7.41 7.58 0.032724306 Up 0.119335063 Dhx35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 K13117|1|0.0|1264|rno:362260|ATP-dependent RNA helicase DDX35 [EC:3.6.4.13] GO:0005681//spliceosomal complex "GO:0042623//ATPase activity, coupled;GO:0032550;GO:0032550;GO:0042623//ATPase activity, coupled" - gi|21919420|ref|NP_665685.1|/0/probable ATP-dependent RNA helicase DHX35 isoform a [Mus musculus] 170760 3487 7.41 7.58 0.032724306 Up 0.119335063 Acbd3 acyl-Coenzyme A binding domain containing 3 - GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane - GO:0006629//lipid metabolic process "gi|148681200|gb|EDL13147.1|/1.94391e-82/acyl-Coenzyme A binding domain containing 3, isoform CRA_a, partial [Mus musculus]" 68979 3168 7.12 6.953333333 -0.034172489 Down 0.119335063 Nol11 nucleolar protein 11 K20478|1|2e-12|77.8|sko:100372617|golgin subfamily B member 1 GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen - - gi|238550124|ref|NP_598463.2|/0/nucleolar protein 11 isoform 1 [Mus musculus] 239170 4051 8.833333333 9.003333333 0.02750128 Up 0.119335063 Fam160b2 "family with sequence similarity 160, member B2" - - - - gi|257196165|ref|NP_919326.1|/0/protein FAM160B2 [Mus musculus] 433426 2409 0.266666667 0.303333333 0.185866545 Up 0.119297454 Gm13490 predicted gene 13490 - - - - gi|148694947|gb|EDL26894.1|/8.04803e-37/mCG1051061 [Mus musculus] 50762 1268.21 37.66 38.22 0.021294778 Up 0.119297454 Fbxo6 F-box protein 6 K10100|1|4e-171|603|mmu:50762|F-box protein 6 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006259//DNA metabolic process;GO:0032446//protein modification by small protein conjugation;GO:0033554//cellular response to stress;GO:0009100//glycoprotein metabolic process;GO:0035966//response to topologically incorrect protein;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006259//DNA metabolic process;GO:0032446//protein modification by small protein conjugation;GO:0033554//cellular response to stress;GO:0009100//glycoprotein metabolic process;GO:0035966//response to topologically incorrect protein;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006259//DNA metabolic process;GO:0032446//protein modification by small protein conjugation;GO:0033554//cellular response to stress;GO:0009100//glycoprotein metabolic process;GO:0035966//response to topologically incorrect protein;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006259//DNA metabolic process;GO:0032446//protein modification by small protein conjugation;GO:0033554//cellular response to stress;GO:0009100//glycoprotein metabolic process;GO:0035966//response to topologically incorrect protein;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006259//DNA metabolic process;GO:0032446//protein modification by small protein conjugation;GO:0033554//cellular response to stress;GO:0009100//glycoprotein metabolic process;GO:0035966//response to topologically incorrect protein "gi|148682859|gb|EDL14806.1|/1.15327e-172/F-box only protein 6b, isoform CRA_b, partial [Mus musculus]" 328830 1716 0.323333333 0.283333333 -0.190521906 Down 0.119297454 A530064D06Rik RIKEN cDNA A530064D06 gene K14362|1|3e-26|122|mmu:58217|triggering receptor expressed on myeloid cells 1;K06742|3|7e-20|101|cge:100771904|natural cytotoxicity triggering receptor 2 - - - - 78052 586 0.36 0.316666667 -0.185031894 Down 0.119297454 Tmem190 transmembrane protein 190 K20317|1|1e-07|58.5|asn:102377268|c-Jun-amino-terminal kinase-interacting protein 4 GO:0031224//intrinsic component of membrane GO:0005515//protein binding - gi|254675164|ref|NP_084304.1|/6.60506e-77/transmembrane protein 190 precursor [Mus musculus] 50876 9893 0.33 0.29 -0.186413124 Down 0.119297454 Tmod2 tropomodulin 2 K10370|1|0.0|646|mmu:50876|tropomodulin - - - - 67026 1581.79 32.93 32.37666667 -0.024448051 Down 0.119212832 Thap4 THAP domain containing 4 K09228|1|1e-13|81.3|pbi:103049051|KRAB domain-containing zinc finger protein;K16855|4|3e-10|69.7|api:100166838|U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64] - GO:0003676//nucleic acid binding;GO:0043169//cation binding - gi|672066179|ref|XP_008765602.1|/2.78581e-93/PREDICTED: THAP domain-containing protein 4 isoform X1 [Rattus norvegicus] 214922 2334 0.126666667 0.096666667 -0.389946518 Down 0.11916582 Slc39a2 "solute carrier family 39 (zinc transporter), member 2" "K14709|1|1e-144|516|mmu:214922|solute carrier family 39 (zinc transporter), member 1/2/3" GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0046915//transition metal ion transmembrane transporter activity GO:0006829//zinc II ion transport gi|225543187|ref|NP_001034765.2|/1.24312e-143/zinc transporter ZIP2 [Mus musculus] 13639 1596 0.123333333 0.093333333 -0.402098444 Down 0.11916582 Efna4 ephrin A4 K05462|1|2e-112|408|mmu:13639|ephrin-A GO:0031224//intrinsic component of membrane GO:0005102//receptor binding - gi|110835739|ref|NP_031936.2|/1.73046e-111/ephrin-A4 precursor [Mus musculus] 14191 3353 0.103333333 0.136666667 0.403355694 Up 0.11916582 Fgr "FGR proto-oncogene, Src family tyrosine kinase" K08891|1|0.0|1072|mmu:14191|tyrosine-protein kinase Fgr [EC:2.7.10.2] - - - - 67733 2738 0.873333333 0.93 0.09069831 Up 0.119100004 Itgb3bp integrin beta 3 binding protein (beta3-endonexin) K11510|1|2e-92|343|mmu:67733|centromere protein R "GO:0031981//nuclear lumen;GO:0000775//chromosome, centromeric region" - "GO:0012501//programmed cell death;GO:0000087//mitotic M phase;GO:0007166//cell surface receptor signaling pathway;GO:0006351//transcription, DNA-templated" gi|13385850|ref|NP_080624.1|/1.7386e-91/centromere protein R [Mus musculus] 103268 2208.45 0.966666667 1.026666667 0.086877451 Up 0.119100004 Cep57l1 centrosomal protein 57-like 1 K16762|1|0.0|659|rno:294519|centrosomal protein CEP57 GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0000226//microtubule cytoskeleton organization;GO:0000226//microtubule cytoskeleton organization;GO:0000226//microtubule cytoskeleton organization;GO:0000226//microtubule cytoskeleton organization "gi|148673040|gb|EDL04987.1|/0/RIKEN cDNA 2410017P07, isoform CRA_b, partial [Mus musculus]" 668923 7164 0.896666667 0.953333333 0.088408974 Up 0.119100004 Zfp442 zinc finger protein 442 K09228|1|0.0|1463|mmu:668923|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|889029083|ref|NP_001297574.1|/0/zinc finger protein 442 [Mus musculus] 244556 2359 0.923333333 0.98 0.085930179 Up 0.119100004 Zfp791 zinc finger protein 791 K09228|1|0.0|1142|mmu:244556|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|83627693|ref|NP_001032834.1|/0/zinc finger protein 791 [Mus musculus] 12763 9370.86 1.006666667 0.946666667 -0.08865762 Down 0.119100004 Cmah cytidine monophospho-N-acetylneuraminic acid hydroxylase K08080|1|0.0|1225|mmu:12763|CMP-N-acetylneuraminate monooxygenase [EC:1.14.18.2] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0043169//cation binding;GO:0016716//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen;GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding;GO:0016716//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen;GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding;GO:0016716//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen;GO:0051536//iron-sulfur cluster binding;GO:0043169//cation binding;GO:0016716//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen;GO:0051536//iron-sulfur cluster binding" GO:0051234//establishment of localization;GO:0009225//nucleotide-sugar metabolic process;GO:0006040//amino sugar metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization;GO:0009225//nucleotide-sugar metabolic process;GO:0006040//amino sugar metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization;GO:0009225//nucleotide-sugar metabolic process;GO:0006040//amino sugar metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0051234//establishment of localization;GO:0009225//nucleotide-sugar metabolic process;GO:0006091//generation of precursor metabolites and energy "gi|148700555|gb|EDL32502.1|/0/cytidine monophospho-N-acetylneuraminic acid hydroxylase, isoform CRA_c, partial [Mus musculus]" 54126 4506.35 37.98 37.44333333 -0.020531031 Down 0.119081199 Arhgef7 Rho guanine nucleotide exchange factor (GEF7) K13710|1|0.0|1286|lve:103085980|Rho guanine nucleotide exchange factor 7 GO:0032991//macromolecular complex;GO:0044297//cell body;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0042995//cell projection;GO:0044444//cytoplasmic part GO:0030695//GTPase regulator activity;GO:0008289//lipid binding;GO:0019900//kinase binding GO:0048731//system development;GO:0043087//regulation of GTPase activity;GO:0007266//Rho protein signal transduction;GO:0006915//apoptotic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0030031//cell projection assembly gi|125987791|sp|Q9ES28.2|ARHG7_MOUSE/0/RecName: Full=Rho guanine nucleotide exchange factor 7; AltName: Full=Beta-Pix; AltName: Full=PAK-interacting exchange factor beta; AltName: Full=p85SPR 100503962 936 0.113333333 0.146666667 0.371968777 Up 0.11896837 Gm16701 "predicted gene, 16701" - - - - - 14238 2366 0.146666667 0.113333333 -0.371968777 Down 0.11896837 Foxf2 forkhead box F2 K09399|1|2e-149|532|mmu:14238|forkhead box protein F - - - gi|2661754|emb|CAA72972.1|/1.30597e-148/lun [Mus musculus] 20269 9560 0.146666667 0.113333333 -0.371968777 Down 0.11896837 Scn3a "sodium channel, voltage-gated, type III, alpha" K04836|1|0.0|3331|mmu:20269|voltage-gated sodium channel type III alpha - - - - 270091 2431 0.116666667 0.15 0.362570079 Up 0.11896837 Lrrc36 leucine rich repeat containing 36 K16594|1|0.0|1197|mmu:270091|leucine-rich repeat-containing protein 36 - - - gi|85701864|ref|NP_001028543.1|/0/leucine-rich repeat-containing protein 36 isoform 3 [Mus musculus] 319849 1909 0.106666667 0.136666667 0.357552005 Up 0.11896837 Plxna4os1 "plexin A4, opposite strand 1" - - - - gi|148681759|gb|EDL13706.1|/1.30927e-23/mCG147464 [Mus musculus] 67703 3701 0.103333333 0.133333333 0.367731785 Up 0.11896837 Kirrel3 kin of IRRE like 3 (Drosophila) K18273|1|2e-69|267|asn:102383405|alpha-tectorin;K14319|3|3e-32|144|bfo:BRAFLDRAFT_126584|Ran GTPase-activating protein 1;K16680|4|4e-26|123|dpe:Dper_GL18842|echinoid GO:0030425//dendrite;GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0031224//intrinsic component of membrane GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding;GO:0019904//protein domain specific binding GO:0021730//trigeminal sensory nucleus development;GO:0048534//hematopoietic or lymphoid organ development;GO:0021730//trigeminal sensory nucleus development;GO:0048534//hematopoietic or lymphoid organ development;GO:0021730//trigeminal sensory nucleus development;GO:0016477//cell migration;GO:0048534//hematopoietic or lymphoid organ development;GO:0021730//trigeminal sensory nucleus development;GO:0016477//cell migration;GO:0048534//hematopoietic or lymphoid organ development;GO:0021730//trigeminal sensory nucleus development;GO:0016477//cell migration;GO:0048534//hematopoietic or lymphoid organ development gi|29824425|ref|NP_080600.1|/0/kin of IRRE-like protein 3 isoform B precursor [Mus musculus] 12944 1698 0.093333333 0.12 0.362570079 Up 0.11896837 Crp "C-reactive protein, pentraxin-related" K16143|1|2e-129|465|mmu:12944| GO:0043005//neuron projection;GO:0044421 GO:0032934//sterol binding;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0071813//lipoprotein particle binding GO:0010742//macrophage derived foam cell differentiation;GO:0002526//acute inflammatory response;GO:0051592//response to calcium ion;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0043623//cellular protein complex assembly;GO:0010976//positive regulation of neuron projection development;GO:0010883//regulation of lipid storage gi|162138926|ref|NP_031794.3|/1.68683e-128/C-reactive protein precursor [Mus musculus] 66084 1849 34.55 34.03333333 -0.02173725 Down 0.118846139 Rmnd1 required for meiotic nuclear division 1 homolog K01920|1|2e-57|226|aec:105145173|glutathione synthase [EC:6.3.2.3] GO:0043231//intracellular membrane-bounded organelle - GO:0010467//gene expression gi|226423886|ref|NP_079619.4|/0/required for meiotic nuclear division protein 1 homolog [Mus musculus] 17684 1980 41.68 41.17 -0.017761829 Down 0.118780323 Cited2 "Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2" - GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0019904//protein domain specific binding;GO:0019899//enzyme binding GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0003206//cardiac chamber morphogenesis;GO:0014020;GO:0006915//apoptotic process;GO:0008406//gonad development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0001893//maternal placenta development;GO:0016337//single organismal cell-cell adhesion;GO:0001825//blastocyst formation;GO:0051726//regulation of cell cycle;GO:0051094//positive regulation of developmental process;GO:0009967//positive regulation of signal transduction;GO:0016477//cell migration;GO:0003140//determination of left/right asymmetry in lateral mesoderm;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0009798//axis specification;GO:0035270//endocrine system development;GO:0009605//response to external stimulus;GO:0007568//aging;GO:0003281//ventricular septum development;GO:0048844//artery morphogenesis;GO:0002088//lens development in camera-type eye;GO:0031076//embryonic camera-type eye development;GO:0048545//response to steroid hormone;GO:0003143//embryonic heart tube morphogenesis;GO:0002573//myeloid leukocyte differentiation;GO:0048645//organ formation;GO:0030218//erythrocyte differentiation;GO:0014032//neural crest cell development;GO:0007519//skeletal muscle tissue development gi|675654626|ref|XP_008993415.1|/1.52514e-123/PREDICTED: cbp/p300-interacting transactivator 2 [Callithrix jacchus] 381314 3540 33.85 34.35666667 0.021434237 Up 0.118780323 Iars2 "isoleucine-tRNA synthetase 2, mitochondrial" K01870|1|0.0|2013|mmu:381314|isoleucyl-tRNA synthetase [EC:6.1.1.5] GO:0044429 GO:0032550;GO:0052689//carboxylic ester hydrolase activity;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation "gi|38490690|ref|NP_941055.1|/0/isoleucine--tRNA ligase, mitochondrial precursor [Mus musculus]" 80289 3139 2.02 2.1 0.056034035 Up 0.118733311 Lysmd3 "LysM, putative peptidoglycan-binding, domain containing 3" - GO:0031224//intrinsic component of membrane - GO:0044036 gi|13385022|ref|NP_084533.1|/4.15049e-169/lysM and putative peptidoglycan-binding domain-containing protein 3 [Mus musculus] 74043 4091.99 1.986666667 1.903333333 -0.061821585 Down 0.118733311 Pex26 peroxisomal biogenesis factor 26 K13340|1|1e-131|474|mmu:74043|peroxin-26 GO:0031231//intrinsic component of peroxisomal membrane;GO:0031224//intrinsic component of membrane;GO:0005777//peroxisome;GO:0031231//intrinsic component of peroxisomal membrane GO:0019899//enzyme binding;GO:0019899//enzyme binding;GO:0019899//enzyme binding GO:0006625//protein targeting to peroxisome;GO:0006625//protein targeting to peroxisome;GO:0006625//protein targeting to peroxisome gi|755571577|ref|NP_001291703.1|/3.92163e-60/peroxisome assembly protein 26 isoform 3 [Mus musculus] 104910 1609 1.876666667 1.956666667 0.060225581 Up 0.118733311 Slc25a47 "solute carrier family 25, member 47" "K15123|1|2e-144|515|mmu:104910|solute carrier family 25, member 45/47" GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane - GO:0044763 "gi|32822820|gb|AAH55027.1|/2.94799e-151/AI132487 protein, partial [Mus musculus]" 233805 5618 1.873333333 1.956666667 0.062790373 Up 0.118733311 Dcun1d3 "DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)" K17823|1|4e-178|629|mmu:233805|DCN1-like protein 3 GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0009411//response to UV;GO:0000084//mitotic S phase;GO:0016049//cell growth;GO:0010212//response to ionizing radiation;GO:0006915//apoptotic process;GO:0009411//response to UV;GO:0000084//mitotic S phase;GO:0016049//cell growth;GO:0010212//response to ionizing radiation;GO:0006915//apoptotic process gi|27734156|ref|NP_775584.1|/3.53029e-177/DCN1-like protein 3 [Mus musculus] 67158 2810 1.75 1.83 0.064488726 Up 0.118733311 Sft2d3 SFT2 domain containing 3 - - - - gi|12848307|dbj|BAB27904.1|/6.47308e-96/unnamed protein product [Mus musculus] 105372 4071 1.903333333 1.823333333 -0.061949913 Down 0.118733311 Utp15 UTP15 small subunit processome component K14549|1|0.0|1016|mmu:105372|U3 small nucleolar RNA-associated protein 15 GO:0031981//nuclear lumen - GO:0042254//ribosome biogenesis gi|30725776|ref|NP_849249.1|/0/U3 small nucleolar RNA-associated protein 15 homolog [Mus musculus] 19011 2404 1.95 1.87 -0.060435854 Down 0.118733311 Endou "endonuclease, polyU-specific" K14648|1|0.0|885|mmu:19011|poly(U)-specific endoribonuclease [EC:3.1.-.-] GO:0044424;GO:0044424 "GO:0004519//endonuclease activity;GO:0043169//cation binding;GO:0038024//cargo receptor activity;GO:0001871;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0004519//endonuclease activity;GO:0043169//cation binding;GO:0038024//cargo receptor activity;GO:0001871;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0002376//immune system process;GO:0019538//protein metabolic process;GO:0002376//immune system process gi|274317467|ref|NP_001162164.1|/0/poly(U)-specific endoribonuclease isoform 2 precursor [Mus musculus] 50790 5047.64 1.913333333 1.836666667 -0.058998418 Down 0.118733311 Acsl4 acyl-CoA synthetase long-chain family member 4 K01897|1|0.0|1447|mmu:50790|long-chain acyl-CoA synthetase [EC:6.2.1.3] GO:0042579//microbody;GO:0044297//cell body;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0042579//microbody;GO:0044297//cell body;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0042579//microbody;GO:0044297//cell body;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane GO:0016878//acid-thiol ligase activity;GO:0032550;GO:0015645//fatty acid ligase activity;GO:0016878//acid-thiol ligase activity;GO:0032550;GO:0015645//fatty acid ligase activity;GO:0016878//acid-thiol ligase activity;GO:0032550;GO:0015645//fatty acid ligase activity GO:0016358//dendrite development;GO:0006639//acylglycerol metabolic process;GO:0007565//female pregnancy;GO:0006631//fatty acid metabolic process;GO:0032304//negative regulation of icosanoid secretion;GO:0016049//cell growth;GO:0016358//dendrite development;GO:0006639//acylglycerol metabolic process;GO:0034097//response to cytokine;GO:0007565//female pregnancy;GO:0006631//fatty acid metabolic process;GO:0032304//negative regulation of icosanoid secretion;GO:0016049//cell growth;GO:0031667//response to nutrient levels;GO:0016358//dendrite development;GO:0006639//acylglycerol metabolic process;GO:0034097//response to cytokine;GO:0007565//female pregnancy;GO:0006631//fatty acid metabolic process;GO:0032304//negative regulation of icosanoid secretion;GO:0016049//cell growth;GO:0031667//response to nutrient levels "gi|148682802|gb|EDL14749.1|/0/acyl-CoA synthetase long-chain family member 4, isoform CRA_b, partial [Mus musculus]" 109275 2381 2.156666667 2.073333333 -0.056851132 Down 0.118733311 Actr5 ARP5 actin-related protein 5 K11672|1|0.0|1038|mmu:109275|actin-related protein 5 - - - gi|408360318|sp|Q80US4.3|ARP5_MOUSE/0/RecName: Full=Actin-related protein 5 18646 2054 0.153333333 0.12 -0.353636955 Down 0.118648689 Prf1 perforin 1 (pore forming protein) K07818|1|0.0|1144|mmu:18646|perforin 1 GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0044440;GO:0031982//vesicle;GO:0044421 GO:0046872//metal ion binding;GO:0015267//channel activity GO:0012501//programmed cell death;GO:0002347//response to tumor cell;GO:0097305//response to alcohol;GO:0051259//protein oligomerization;GO:0048511//rhythmic process;GO:0002252 gi|225735600|ref|NP_035203.3|/0/perforin-1 precursor [Mus musculus] 14027 6398 0.14 0.11 -0.347923303 Down 0.118648689 Evpl envoplakin K10383|1|0.0|3239|mmu:14027|envoplakin GO:0005856//cytoskeleton GO:0005515//protein binding GO:0030216//keratinocyte differentiation;GO:0006464//cellular protein modification process gi|111185907|ref|NP_079552.3|/0/envoplakin [Mus musculus] 100503427 3977 0.096666667 0.123333333 0.351472371 Up 0.118648689 Gm10390 predicted gene 10390 K14787|1|2e-23|114|mmu:74111|multiple RNA-binding domain-containing protein 1 - - - - 72301 5921 0.11 0.14 0.347923303 Up 0.118648689 1810041L15Rik RIKEN cDNA 1810041L15 gene - GO:0031224//intrinsic component of membrane - - "gi|148672505|gb|EDL04452.1|/2.23546e-97/mCG141069, partial [Mus musculus]" 77569 6063.84 32.76 33.26333333 0.021997392 Up 0.118582873 Limch1 LIM and calponin homology domains 1 K06084|1|7e-78|296|ptr:452604|F-box protein 20 - - - gi|371122487|ref|NP_001243051.1|/0/LIM and calponin homology domains-containing protein 1 isoform 2 [Mus musculus] 60321 2722 43.52 44.02 0.016480589 Up 0.118582873 Wbp11 WW domain binding protein 11 K12866|1|9e-159|563|mmu:60321|WW domain-binding protein 11 GO:0016604//nuclear body GO:0019904//protein domain specific binding;GO:0019888//protein phosphatase regulator activity GO:0019222//regulation of metabolic process;GO:0042254//ribosome biogenesis;GO:0006396//RNA processing gi|74192857|dbj|BAE34938.1|/0/unnamed protein product [Mus musculus] 77407 2181 29.76333333 30.26333333 0.024034791 Up 0.118582873 Rab35 "RAB35, member RAS oncogene family" K07876|1|2e-92|343|cjo:107321241|Ras-related protein Rab-35 GO:0048770;GO:0030139//endocytic vesicle;GO:0012505//endomembrane system;GO:0044421;GO:0044459 GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0043168//anion binding GO:0044765//single-organism transport;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction gi|612014742|ref|XP_007490396.1|/9.17547e-93/PREDICTED: LOW QUALITY PROTEIN: ras-related protein Rab-35 [Monodelphis domestica] 15111 2235 44.40666667 44.91 0.016260441 Up 0.118582873 Hand2 heart and neural crest derivatives expressed transcript 2 K18486|1|2e-83|312|ngi:103745219|heart-and neural crest derivatives-expressed protein 2 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin "GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding;GO:0042802//identical protein binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding" GO:0030326//embryonic limb morphogenesis;GO:0048534//hematopoietic or lymphoid organ development;GO:0007631//feeding behavior;GO:0043009//chordate embryonic development;GO:0007423//sensory organ development;GO:0014070//response to organic cyclic compound;GO:0051100//negative regulation of binding;GO:0042476//odontogenesis;GO:0001649//osteoblast differentiation;GO:0048844//artery morphogenesis;GO:0048666//neuron development;GO:0003211//cardiac ventricle formation;GO:0006366//transcription from RNA polymerase II promoter;GO:0003143//embryonic heart tube morphogenesis;GO:0048483//autonomic nervous system development;GO:0010659//cardiac muscle cell apoptotic process;GO:0003264//regulation of cardioblast proliferation;GO:0007368//determination of left/right symmetry;GO:0001755//neural crest cell migration;GO:0071527;GO:0032526//response to retinoic acid;GO:0042421//norepinephrine biosynthetic process;GO:0043388//positive regulation of DNA binding gi|829796090|ref|XP_012626135.1|/5.56951e-85/PREDICTED: heart- and neural crest derivatives-expressed protein 2 [Microcebus murinus] 103284 2102 7.013333333 7.17 0.03187282 Up 0.118488849 Zc3h10 zinc finger CCCH type containing 10 K14943|1|3e-07|60.1|isc:IscW_ISCW014804|muscleblind - GO:0046872//metal ion binding - "gi|148692634|gb|EDL24581.1|/0/zinc finger CCCH type containing 10, partial [Mus musculus]" 74204 4531.75 7.03 6.873333333 -0.032514762 Down 0.118488849 Xpo6 exportin 6 "K15001|1|1e-16|92.0|dpe:Dper_GL20168|cytochrome P450, family 4 [EC:1.14.-.-]" GO:0005635//nuclear envelope;GO:0016020//membrane;GO:0031981//nuclear lumen;GO:0005635//nuclear envelope;GO:0016020//membrane;GO:0031981//nuclear lumen GO:0022892//substrate-specific transporter activity;GO:0022892//substrate-specific transporter activity GO:0006886//intracellular protein transport;GO:0006886//intracellular protein transport gi|37537529|ref|NP_083092.2|/0/exportin-6 isoform 2 [Mus musculus] 623230 1370 7.78 7.616666667 -0.030610396 Down 0.118488849 Tmem200b transmembrane protein 200B "K19721|1|3e-34|148|pps:103783253|collagen, type V/XI/XXIV/XXVII, alpha" - - - gi|318067976|ref|NP_001188296.1|/3.46977e-102/transmembrane protein 200B [Mus musculus] 227624 3173 41.17 40.68 -0.017273769 Down 0.118488849 Rabl6 "RAB, member RAS oncogene family-like 6" - GO:0043231//intracellular membrane-bounded organelle GO:0032550 GO:0035556//intracellular signal transduction "gi|35193107|gb|AAH58585.1|/0/B230208H17Rik protein, partial [Mus musculus]" 68107 2228 7.116666667 7.273333333 0.031415032 Up 0.118488849 Cntd1 cyclin N-terminal domain containing 1 - - - - gi|32527717|gb|AAP86260.1|/4.13604e-173/Ac2-059 [Rattus norvegicus] 72039 2992 31.51 31.01666667 -0.022766105 Down 0.118488849 Mccc1 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) K01968|1|0.0|1346|mmu:72039|3-methylcrotonyl-CoA carboxylase alpha subunit [EC:6.4.1.4] GO:0019866//organelle inner membrane;GO:0044429 "GO:0043169//cation binding;GO:0032550;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0016421//CoA carboxylase activity" GO:0006551//leucine metabolic process "gi|186700620|ref|NP_076133.3|/0/methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial [Mus musculus]" 15950 4167.79 8.333333333 8.496666667 0.028003278 Up 0.118488849 Ifi203 interferon activated gene 203 K12971|1|2e-47|194|mmu:26388|interferon-activable protein 202;K12966|5|2e-36|158|ngi:103740252|absent in melanoma 2 - - GO:0035456//response to interferon-beta;GO:0035456//response to interferon-beta gi|703491576|ref|NP_001289580.1|/0/interferon-activable protein 203 isoform 3 [Mus musculus] 72355 991.06 9.013333333 9.176666667 0.025909458 Up 0.118488849 Cdpf1 "cysteine rich, DPF motif domain containing 1" - - - - gi|194733721|ref|NP_001124168.1|/8.91662e-64/cysteine-rich DPF motif domain-containing protein 1 [Rattus norvegicus] 14208 2165 28.76666667 29.26 0.024531711 Up 0.118488849 Ppm1g "protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform" K17499|1|0.0|924|mmu:14208|protein phosphatase 1G [EC:3.1.3.16] GO:0031981//nuclear lumen GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity GO:0006470//protein dephosphorylation;GO:0022402//cell cycle process gi|6679793|ref|NP_032040.1|/0/protein phosphatase 1G [Mus musculus] 266692 3503.24 9.343333333 9.18 -0.025443185 Down 0.118488849 Cpne1 copine I K11348|1|5e-11|73.2|apla:101800649|bromodomain and PHD finger-containing protein 1;K19906|2|2e-10|71.2|sko:100376714|synaptotagmin-6;K06491|3|2e-08|64.7|cin:100183448|neural cell adhesion molecule;K19909|4|3e-07|60.5|crg:105318275|synaptotagmin-9;K17632|5|1e-06|58.9|tup:102492287|RAS protein activator-like 1 - GO:0005543//phospholipid binding;GO:0005543//phospholipid binding - gi|25141330|ref|NP_733467.1|/0/copine-1 [Mus musculus] 13056 2474 8.71 8.546666667 -0.027310863 Down 0.118488849 Cyb561 cytochrome b-561 K08360|1|4e-115|418|mmu:13056|cytochrome b-561 [EC:1.16.5.1] GO:0031982//vesicle;GO:0031224//intrinsic component of membrane "GO:0043169//cation binding;GO:0016723//oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor" GO:0051234//establishment of localization;GO:0044710;GO:0006091//generation of precursor metabolites and energy "gi|148702301|gb|EDL34248.1|/2.47427e-119/cytochrome b-561, isoform CRA_b [Mus musculus]" 71701 2704 8.083333333 8.243333333 0.028277492 Up 0.118488849 Pnpt1 polyribonucleotide nucleotidyltransferase 1 K00962|1|0.0|1388|mmu:71701|polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] GO:0016020//membrane;GO:0000177//cytoplasmic exosome (RNase complex);GO:0005740//mitochondrial envelope GO:0016779//nucleotidyltransferase activity;GO:0070717//poly-purine tract binding;GO:0008187//poly-pyrimidine tract binding;GO:0008408//3'-5' exonuclease activity GO:0071047//polyadenylation-dependent mRNA catabolic process;GO:0000963//mitochondrial RNA processing;GO:0040007//growth;GO:0035927//RNA import into mitochondrion;GO:0043467//regulation of generation of precursor metabolites and energy;GO:0010587//miRNA catabolic process;GO:0007050//cell cycle arrest;GO:0006402//mRNA catabolic process;GO:0000957//mitochondrial RNA catabolic process;GO:0080135//regulation of cellular response to stress;GO:0051260//protein homooligomerization;GO:0006979//response to oxidative stress;GO:0006378//mRNA polyadenylation;GO:0035456//response to interferon-beta "gi|25188204|ref|NP_082145.1|/0/polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor [Mus musculus]" 12526 1416 1.39 1.323333333 -0.070908376 Down 0.118423032 Cd8b1 "CD8 antigen, beta chain 1" "K06459|1|5e-96|353|mmu:12526|CD8B antigen, beta polypeptide" GO:0009986//cell surface;GO:0031224//intrinsic component of membrane - - gi|6753358|ref|NP_033988.1|/4.29474e-95/T-cell surface glycoprotein CD8 beta chain precursor [Mus musculus] 320507 1190 1.343333333 1.413333333 0.073284426 Up 0.118423032 D930015M05Rik RIKEN cDNA D930015M05 gene K02295|1|6e-21|104|mmu:12953|cryptochrome - - - - 52202 3445 1.35 1.416666667 0.069540933 Up 0.118423032 Rbm34 RNA binding motif protein 34 K14837|1|0.0|669|mmu:52202|nucleolar protein 12 GO:0031981//nuclear lumen GO:0003676//nucleic acid binding - gi|42794007|ref|NP_766350.2|/0/RNA-binding protein 34 [Mus musculus] 68404 1622 1.43 1.5 0.068947354 Up 0.118423032 Nrn1 neuritin 1 K05726|1|1e-15|87.4|lcm:102355909|breast cancer anti-estrogen resistance 1 GO:0008328//ionotropic glutamate receptor complex - GO:0048667//cell morphogenesis involved in neuron differentiation gi|23956286|ref|NP_705757.1|/5.96272e-59/neuritin precursor [Mus musculus] 240064 6025 1.41 1.48 0.069902013 Up 0.118423032 Zfp799 zinc finger protein 799 K09228|1|0.0|1255|rno:494339|KRAB domain-containing zinc finger protein - GO:0043169//cation binding;GO:0043169//cation binding - gi|148539915|ref|NP_796333.3|/0/zinc finger protein 799 isoform 1 [Mus musculus] 329260 8072 1.473333333 1.406666667 -0.066803371 Down 0.118423032 Dennd1b DENN/MADD domain containing 1B K20160|1|0.0|1451|mmu:329260|DENN domain-containing protein 1 GO:0031982//vesicle;GO:0044424;GO:0031982//vesicle;GO:0044424 GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0019222//regulation of metabolic process;GO:0045184//establishment of protein localization;GO:0019222//regulation of metabolic process;GO:0045184//establishment of protein localization gi|262073029|ref|NP_001159973.1|/0/DENN domain-containing protein 1B isoform 1 [Mus musculus] 22758 4435 1.333333333 1.403333333 0.073820233 Up 0.118423032 Zscan12 zinc finger and SCAN domain containing 12 K09230|1|0.0|1009|mmu:22758|SCAN domain-containing zinc finger protein - - - - 230753 4350 29.03666667 28.56 -0.023879866 Down 0.11841363 Thrap3 thyroid hormone receptor associated protein 3 K13112|1|0.0|1041|xla:100505427|thyroid hormone receptor-associated protein 3 GO:0031981//nuclear lumen;GO:0043234//protein complex "GO:0003712//transcription cofactor activity;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0008134//transcription factor binding" "GO:0006366//transcription from RNA polymerase II promoter;GO:0043488//regulation of mRNA stability;GO:0006402//mRNA catabolic process;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0030518//intracellular steroid hormone receptor signaling pathway" gi|347300437|ref|NP_001184195.1|/0/thyroid hormone receptor-associated protein 3 [Xenopus laevis] 245368 4658 0.646666667 0.596666667 -0.116097065 Down 0.11841363 Zfp300 zinc finger protein 300 K09228|1|0.0|1320|mmu:245368|KRAB domain-containing zinc finger protein - - - gi|569008758|ref|XP_006527690.1|/0/PREDICTED: zinc finger protein 300 isoform X1 [Mus musculus] 27028 4573 0.66 0.606666667 -0.12156198 Down 0.11841363 Ermap erythroblast membrane-associated protein K06712|1|0.0|1079|mmu:27028|butyrophilin GO:0031982//vesicle;GO:0044424;GO:0031224//intrinsic component of membrane - - "gi|148698520|gb|EDL30467.1|/0/erythroblast membrane-associated protein, isoform CRA_a, partial [Mus musculus]" 75869 3594 0.586666667 0.636666667 0.117997209 Up 0.11841363 Arl5b ADP-ribosylation factor-like 5B K07950|1|6e-100|368|bacu:103009662|ADP-ribosylation factor-like protein 5B GO:0044464 GO:0032550 GO:0035556//intracellular signal transduction gi|27229225|ref|NP_083742.2|/5.27392e-99/ADP-ribosylation factor-like protein 5B [Mus musculus] 76669 1110 0.61 0.663333333 0.120924782 Up 0.11841363 1700128F08Rik U1-snRNP binding protein homolog pseudogene K13155|1|6e-28|127|cge:100772584|U11/U12 small nuclear ribonucleoprotein 35 kDa protein - - - - 13024 1368.28 30.56 31.04333333 0.022638934 Up 0.11841363 Ctla2a cytotoxic T lymphocyte-associated protein 2 alpha K01365|1|4e-30|135|cge:100756494|cathepsin L [EC:3.4.22.15];K09601|3|4e-24|115|rno:498688|cathepsin R [EC:3.4.22.-] GO:0043005//neuron projection;GO:0043005//neuron projection GO:0005488//binding;GO:0005488//binding GO:0006954//inflammatory response;GO:0045066//regulatory T cell differentiation;GO:0010466//negative regulation of peptidase activity;GO:0016485//protein processing;GO:0006954//inflammatory response;GO:0045066//regulatory T cell differentiation;GO:0010466//negative regulation of peptidase activity;GO:0016485//protein processing gi|224809480|ref|NP_031822.2|/2.25321e-74/protein CTLA-2-alpha isoform a precursor [Mus musculus] 57028 2018 0.623333333 0.573333333 -0.120629705 Down 0.11841363 Pdxp "pyridoxal (pyridoxine, vitamin B6) phosphatase" K07758|1|8e-133|476|mmu:57028|pyridoxal phosphatase [EC:3.1.3.74] GO:0030027//lamellipodium;GO:0016020//membrane;GO:0032155;GO:0001726//ruffle;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0016791//phosphatase activity;GO:0043169//cation binding GO:0033198//response to ATP;GO:0007067//mitotic nuclear division;GO:0006464//cellular protein modification process;GO:0030042//actin filament depolymerization;GO:0000910//cytokinesis gi|47059486|ref|NP_064667.2|/6.99057e-132/pyridoxal phosphate phosphatase [Mus musculus] 381967 1474 0.6 0.553333333 -0.116813665 Down 0.11841363 Gm26705 "predicted gene, 26705" - - - - "gi|148684427|gb|EDL16374.1|/1.7503e-38/mCG145257, partial [Mus musculus]" 230673 3588 31.63 31.15 -0.022061393 Down 0.11841363 Ipo13 importin 13 K15436|1|0.0|1561|tgu:100222227|transportin-3 GO:0031074//nucleocytoplasmic shuttling complex;GO:0005635//nuclear envelope GO:0035258//steroid hormone receptor binding;GO:0022892//substrate-specific transporter activity GO:0006886//intracellular protein transport gi|39104529|dbj|BAC98010.2|/0/mKIAA0724 protein [Mus musculus] 12411 2458.01 0.1 0.126666667 0.341036918 Up 0.118394825 Cbs cystathionine beta-synthase K01697|1|0.0|1064|mmu:12411|cystathionine beta-synthase [EC:4.2.1.22] GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0044389//ubiquitin-like protein ligase binding;GO:0016597//amino acid binding;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0016836//hydro-lyase activity;GO:0046906//tetrapyrrole binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0016597//amino acid binding;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0016836//hydro-lyase activity;GO:0046906//tetrapyrrole binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0016597//amino acid binding;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0016836//hydro-lyase activity;GO:0046906//tetrapyrrole binding GO:0009653//anatomical structure morphogenesis;GO:0006563//L-serine metabolic process;GO:0003018;GO:0048771//tissue remodeling;GO:0030799;GO:0009093//cysteine catabolic process;GO:0006915//apoptotic process;GO:0007565//female pregnancy;GO:0036075;GO:0014070//response to organic cyclic compound;GO:0001666//response to hypoxia;GO:0043405//regulation of MAP kinase activity;GO:0019344//cysteine biosynthetic process;GO:0009991//response to extracellular stimulus;GO:0044767//single-organism developmental process;GO:0072593//reactive oxygen species metabolic process;GO:0009653//anatomical structure morphogenesis;GO:0006563//L-serine metabolic process;GO:0003018;GO:0048771//tissue remodeling;GO:0030799;GO:0009093//cysteine catabolic process;GO:0006915//apoptotic process;GO:0007565//female pregnancy;GO:0036075;GO:0014070//response to organic cyclic compound;GO:0001666//response to hypoxia;GO:0043405//regulation of MAP kinase activity;GO:0019344//cysteine biosynthetic process;GO:0009991//response to extracellular stimulus;GO:0044767//single-organism developmental process;GO:0072593//reactive oxygen species metabolic process;GO:0009653//anatomical structure morphogenesis;GO:0006563//L-serine metabolic process;GO:0003018;GO:0048771//tissue remodeling;GO:0030799;GO:0009093//cysteine catabolic process;GO:0006915//apoptotic process;GO:0007565//female pregnancy;GO:0036075;GO:0014070//response to organic cyclic compound;GO:0001666//response to hypoxia;GO:0043405//regulation of MAP kinase activity;GO:0019344//cysteine biosynthetic process;GO:0009991//response to extracellular stimulus;GO:0044767//single-organism developmental process;GO:0072593//reactive oxygen species metabolic process "gi|148708402|gb|EDL40349.1|/0/cystathionine beta-synthase, isoform CRA_c, partial [Mus musculus]" 100504404 887 0.12 0.15 0.321928095 Up 0.118394825 H2-Ea-ps "histocompatibility 2, class II antigen E alpha, pseudogene" "K06752|1|8e-135|481|mmu:100504404|major histocompatibility complex, class II" - - - - 56619 2519 0.103333333 0.13 0.331205908 Up 0.118394825 Clec4e "C-type lectin domain family 4, member e" K10059|1|1e-119|433|mmu:56619|C-type lectin domain family 4 member E GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0050663//cytokine secretion;GO:0002376//immune system process gi|9910162|ref|NP_064332.1|/1.15963e-118/C-type lectin domain family 4 member E [Mus musculus] 18121 1922 0.16 0.126666667 -0.337034987 Down 0.118394825 Nog noggin K04658|1|5e-106|387|pale:102878199|noggin GO:0044421 GO:0042802//identical protein binding GO:0030326//embryonic limb morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0014020;GO:0001704//formation of primary germ layer;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0007498//mesoderm development;GO:0007411//axon guidance;GO:0042471//ear morphogenesis;GO:0030903//notochord development;GO:0001933//negative regulation of protein phosphorylation;GO:0045686//negative regulation of glial cell differentiation;GO:0016477//cell migration;GO:0090184//positive regulation of kidney development;GO:0021536//diencephalon development;GO:0030509//BMP signaling pathway;GO:0001649//osteoblast differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0001840//neural plate development;GO:0008285//negative regulation of cell proliferation;GO:0003002//regionalization;GO:0040036//regulation of fibroblast growth factor receptor signaling pathway;GO:0019827//stem cell population maintenance;GO:0009611//response to wounding;GO:0060300//regulation of cytokine activity gi|958766021|ref|XP_014716547.1|/4.00934e-105/PREDICTED: noggin [Equus asinus] 58801 2654 0.133333333 0.166666667 0.321928095 Up 0.118394825 Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 K10131|1|6e-52|208|mmu:58801|phorbol-12-myristate-13-acetate-induced protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding "GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0008637//apoptotic mitochondrial changes;GO:0045837//negative regulation of membrane potential;GO:0022411;GO:0010822//positive regulation of mitochondrion organization;GO:0097193//intrinsic apoptotic signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0014070//response to organic cyclic compound;GO:0001666//response to hypoxia;GO:0031334//positive regulation of protein complex assembly;GO:0043065//positive regulation of apoptotic process;GO:0006006//glucose metabolic process;GO:0012502//induction of programmed cell death;GO:0002260//lymphocyte homeostasis;GO:0009416//response to light stimulus;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0010212//response to ionizing radiation;GO:0009267//cellular response to starvation;GO:0006839//mitochondrial transport" gi|10946832|ref|NP_067426.1|/4.94934e-51/phorbol-12-myristate-13-acetate-induced protein 1 [Mus musculus] 272382 2786 0.106666667 0.133333333 0.321928095 Up 0.118394825 Spib Spi-B transcription factor (Spi-1/PU.1 related) K09439|1|3e-127|458|mmu:272382|transcription factor Spi-B GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0002573//myeloid leukocyte differentiation;GO:0006351//transcription, DNA-templated" gi|61969658|ref|NP_063919.1|/2.89908e-126/transcription factor Spi-B [Mus musculus] 286942 3433 0.103333333 0.13 0.331205908 Up 0.118394825 Kif19a kinesin family member 19A K10401|1|0.0|1824|mmu:286942|kinesin family member 18/19 GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0003777//microtubule motor activity;GO:0032550 GO:0007019//microtubule depolymerization;GO:0006928//movement of cell or subcellular component gi|156616322|ref|NP_001096085.1|/0/kinesin-like protein KIF19 [Mus musculus] 237887 3516 0.1 0.126666667 0.341036918 Up 0.118394825 Slfn10-ps "schlafen 10, pseudogene" - - - - - 215085 4973 0.1 0.126666667 0.341036918 Up 0.118394825 Slc35f1 "solute carrier family 35, member F1" "K15287|1|0.0|765|mmu:215085|solute carrier family 35, member F1/2" GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization gi|40254332|ref|NP_848790.2|/0/solute carrier family 35 member F1 [Mus musculus] 67552 1911 0.033333333 0.01 -1.736965594 Down 0.118385423 H2afy3 "H2A histone family, member Y3" K11251|1|3e-141|442|ecb:100063355|histone H2A GO:0000228//nuclear chromosome;GO:0000785//chromatin GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity "GO:0040029//regulation of gene expression, epigenetic;GO:0034728//nucleosome organization" gi|194205965|ref|XP_001503760.2|/2.80614e-140/PREDICTED: core histone macro-H2A.2 isoform X2 [Equus caballus] 228592 1925 0.03 0.01 -1.584962501 Down 0.118385423 F830045P16Rik RIKEN cDNA F830045P16 gene K06551|1|6e-32|141|aam:106493210|signal-regulatory protein alpha/beta1/gamma - - - gi|29244066|ref|NP_808321.1|/0/uncharacterized protein LOC228592 [Mus musculus] 654818 2052 0.01 0.03 1.584962501 Up 0.118385423 Smco3 single-pass membrane protein with coiled-coil domains 3 - GO:0031224//intrinsic component of membrane - - "gi|148678626|gb|EDL10573.1|/8.48645e-117/mCG147354, isoform CRA_b, partial [Mus musculus]" 22409 1977 0.03 0.01 -1.584962501 Down 0.118385423 Wnt10a "wingless-type MMTV integration site family, member 10A" "K01357|1|0.0|768|mmu:22409|wingless-type MMTV integration site family, member 10" GO:0031012//extracellular matrix GO:0005515//protein binding GO:0007423//sensory organ development;GO:0007166//cell surface receptor signaling pathway;GO:0010467//gene expression;GO:0048732//gland development;GO:0001942//hair follicle development;GO:0048762//mesenchymal cell differentiation;GO:0042475//odontogenesis of dentin-containing tooth gi|884876431|ref|XP_003464056.2|/0/PREDICTED: protein Wnt-10a [Cavia porcellus] 78767 2069 0.03 0.01 -1.584962501 Down 0.118385423 Efcab11 EF-hand calcium binding domain 11 K02183|1|5e-10|68.9|nve:NEMVE_v1g220271|calmodulin;K16465|2|5e-10|68.9|pxy:105392517|centrin-1 - GO:0043169//cation binding - gi|60687414|ref|NP_084448.1|/1.02127e-85/EF-hand calcium-binding domain-containing protein 11 [Mus musculus] 320974 3475 0.01 0.033333333 1.736965594 Up 0.118385423 Lrrn4 leucine rich repeat neuronal 4 K13023|1|1e-17|95.1|asn:102370171|carboxypeptidase N regulatory subunit;K16351|2|1e-16|91.7|bfo:BRAFLDRAFT_88426|netrin-G2 ligand - - - gi|31542179|ref|NP_796277.2|/0/leucine-rich repeat neuronal protein 4 precursor [Mus musculus] 101533 1475 0.01 0.033333333 1.736965594 Up 0.118385423 Klk9 kallikrein related-peptidase 9 K09618|1|1e-141|505|mmu:101533|kallikrein 9 [EC:3.4.21.-] - - - - 622037 2678 0.01 0.033333333 1.736965594 Up 0.118385423 B930092H01Rik RIKEN cDNA B930092H01 gene - - - - "gi|148694062|gb|EDL26009.1|/1.54539e-60/mCG145422, partial [Mus musculus]" 791422 2220 0.03 0.01 -1.584962501 Down 0.118385423 Gm11426 predicted gene 11426 - - - - - 75811 1835 0.033333333 0.01 -1.736965594 Down 0.118385423 Saxo1 stablizer of axonemal microtubules 1 K08622|1|6e-21|105|mcf:102132317|a disintegrin and metalloproteinase with thrombospondin motifs 7 [EC:3.4.24.-] - - - - 12560 4034.15 0.01 0.03 1.584962501 Up 0.118385423 Cdh3 cadherin 3 "K06796|1|0.0|1494|mmu:12560|cadherin 3, type 1, P-cadherin" GO:0005911//cell-cell junction;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0005911//cell-cell junction;GO:0031224//intrinsic component of membrane;GO:0044424 GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion;GO:0009611//response to wounding;GO:0042221//response to chemical;GO:0016337//single organismal cell-cell adhesion;GO:0009611//response to wounding;GO:0042221//response to chemical gi|83715978|ref|NP_001032898.1|/0/cadherin-3 isoform a preproprotein [Mus musculus] 14563 2317 0.03 0.01 -1.584962501 Down 0.118385423 Gdf5 growth differentiation factor 5 K04664|1|0.0|889|mmu:14563|growth differentiation factor 5 GO:0044421 GO:0005102//receptor binding GO:0006915//apoptotic process;GO:0002062//chondrocyte differentiation;GO:0035264//multicellular organism growth;GO:0008285//negative regulation of cell proliferation;GO:0035108//limb morphogenesis gi|224922797|ref|NP_032135.2|/0/growth/differentiation factor 5 precursor [Mus musculus] 69165 1916 0.01 0.03 1.584962501 Up 0.118385423 Cd209b CD209b antigen K06563|1|6e-163|577|mmu:69165|CD209 antigen GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface GO:0043169//cation binding;GO:0048029//monosaccharide binding;GO:0001871;GO:0043169//cation binding;GO:0048029//monosaccharide binding;GO:0001871;GO:0043169//cation binding;GO:0048029//monosaccharide binding;GO:0001871;GO:0043169//cation binding;GO:0048029//monosaccharide binding;GO:0001871 GO:0001878//response to yeast;GO:0006909//phagocytosis;GO:0009581;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0001878//response to yeast;GO:0006909//phagocytosis;GO:0009581;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0001878//response to yeast;GO:0006909//phagocytosis;GO:0009581;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0001878//response to yeast;GO:0006909//phagocytosis;GO:0009581;GO:0042108//positive regulation of cytokine biosynthetic process "gi|148669308|gb|EDL01255.1|/1.45947e-177/CD209b antigen, isoform CRA_c, partial [Mus musculus]" 545288 1707 0.01 0.033333333 1.736965594 Up 0.118385423 Cyp2c67 "cytochrome P450, family 2, subfamily c, polypeptide 67" "K07413|1|0.0|917|mmu:13099|cytochrome P450, family 2, subfamily C [EC:1.14.14.1]" GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0044710 "gi|67010061|ref|NP_001019890.1|/0/cytochrome P450, family 2, subfamily c, polypeptide 67 precursor [Mus musculus]" 319701 2117 0.01 0.03 1.584962501 Up 0.118385423 Fbxo48 F-box protein 48 - - - - gi|28892819|ref|NP_795956.1|/3.15175e-82/F-box only protein 48 [Mus musculus] 74466 1883 0.033333333 0.01 -1.736965594 Down 0.118385423 4933427G17Rik major facilitator superfamily domain containing 13B - - - - gi|318056062|ref|NP_083231.1|/0/uncharacterized protein LOC74466 [Mus musculus] 18356 1930 0.01 0.033333333 1.736965594 Up 0.118385423 Olfr56 olfactory receptor 56 K04257|1|5e-151|537|mmu:18356|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|81915762|sp|Q8VGD6.1|OLF56_MOUSE/1.41488e-150/RecName: Full=Olfactory receptor 56; AltName: Full=Olfactory receptor 276-1; AltName: Full=Olfactory receptor F7; AltName: Full=Olfactory receptor G3; AltName: Full=Olfactory receptor I-G7 381489 2277 0.03 0.01 -1.584962501 Down 0.118385423 Rxfp1 relaxin/insulin-like family peptide receptor 1 K04306|1|0.0|1554|mmu:381489|relaxin family peptide receptor 1 GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0004888//transmembrane signaling receptor activity GO:0030324//lung development;GO:0043062//extracellular structure organization;GO:0048869//cellular developmental process;GO:0044703;GO:0009653//anatomical structure morphogenesis;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway gi|47059055|ref|NP_997617.1|/0/relaxin receptor 1 precursor [Mus musculus] 393082 1808 0.033333333 0.01 -1.736965594 Down 0.118385423 Mettl7a2 methyltransferase like 7A2 K07755|1|3e-06|56.2|cin:100181209|arsenite methyltransferase [EC:2.1.1.137] - - - gi|61098178|ref|NP_955771.2|/2.91146e-142/methyltransferase like 7A2 [Mus musculus] 328957 1840 0.033333333 0.01 -1.736965594 Down 0.118385423 9330117O12Rik RIKEN cDNA 9330117O12 gene - - - - "gi|148677948|gb|EDL09895.1|/6.17811e-47/mCG145139, partial [Mus musculus]" 15431 3366 0.033333333 0.01 -1.736965594 Down 0.118385423 Hoxd11 homeobox D11 K09296|1|8e-60|235|cfr:106730285|homeobox protein HoxA/C/D11 - - GO:0002062//chondrocyte differentiation;GO:0001822//kidney development;GO:0040007//growth;GO:0045597//positive regulation of cell differentiation;GO:0003156//regulation of organ formation;GO:0030326//embryonic limb morphogenesis;GO:0003002//regionalization;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048704//embryonic skeletal system morphogenesis gi|6680257|ref|NP_032299.1|/2.54598e-102/homeobox protein Hox-D11 [Mus musculus] 625785 2588 0.01 0.03 1.584962501 Up 0.118385423 Gm6623 akirin 1 pseudogene - GO:0005635//nuclear envelope;GO:0031981//nuclear lumen - - gi|31982645|ref|NP_075912.2|/8.0607e-59/akirin-1 [Mus musculus] 78482 1703 0.033333333 0.01 -1.736965594 Down 0.118385423 1700123L14Rik nucleoporin 50 pseudogene K14295|1|3e-157|557|cge:103160839|nuclear pore complex protein Nup50 GO:0005635//nuclear envelope - GO:0050658//RNA transport;GO:0045184//establishment of protein localization;GO:0001838//embryonic epithelial tube formation gi|74199957|dbj|BAE20790.1|/0/unnamed protein product [Mus musculus] 11650 2113 0.03 0.01 -1.584962501 Down 0.118385423 Alppl2 "alkaline phosphatase, placental-like 2" K01077|1|0.0|956|mmu:11650|alkaline phosphatase [EC:3.1.3.1] GO:0031224//intrinsic component of membrane;GO:0043292//contractile fiber GO:0043169//cation binding;GO:0016791//phosphatase activity GO:0006796//phosphate-containing compound metabolic process "gi|124244098|ref|NP_031459.3|/0/alkaline phosphatase, placental-like precursor [Mus musculus]" 621603 2161 0.01 0.033333333 1.736965594 Up 0.118385423 Aldh3b2 "aldehyde dehydrogenase 3 family, member B2" K00129|1|0.0|967|mmu:621603|aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5] - - - "gi|294460012|ref|NP_001170909.1|/0/aldehyde dehydrogenase 3 family, member B2 [Mus musculus]" 320026 1836 0.033333333 0.01 -1.736965594 Down 0.118385423 A330076H08Rik RIKEN cDNA A330076H08 gene - - - - "gi|148682829|gb|EDL14776.1|/1.28267e-44/mCG140291, isoform CRA_a, partial [Mus musculus]" 70594 1834 0.01 0.03 1.584962501 Up 0.118385423 5730460C07Rik RIKEN cDNA 5730460C07 gene - - - - - 17147 2322 0.03 0.01 -1.584962501 Down 0.118385423 Mageb3 "melanoma antigen, family B, 3" K12464|1|2e-35|153|ngi:103745664|melanoma-associated antigen D1 - - - - 320606 1892 0.01 0.033333333 1.736965594 Up 0.118385423 3632454L22Rik RIKEN cDNA 3632454L22 gene - - - - gi|74223419|dbj|BAE21583.1|/3.5377e-42/unnamed protein product [Mus musculus] 69097 1780 0.01 0.033333333 1.736965594 Up 0.118385423 Trim15 tripartite motif-containing 15 K12005|1|1e-154|549|mmu:69097|tripartite motif-containing protein 15 GO:0044464 GO:0046872//metal ion binding;GO:0046914//transition metal ion binding - gi|295424126|ref|NP_001171343.1|/5.92289e-156/tripartite motif-containing protein 15 isoform 1 [Mus musculus] 76652 1892 0.033333333 0.01 -1.736965594 Down 0.118385423 Actrt3 actin related protein T3 "K10354|1|4e-126|454|amj:102562188|actin, alpha skeletal muscle;K05692|3|9e-126|453|cmy:102943914|actin beta/gamma 1" GO:0043073//germ cell nucleus;GO:0043232 GO:0005488//binding - gi|58037457|ref|NP_083966.1|/0/actin-related protein T3 [Mus musculus] 100043188 2247 0.03 0.01 -1.584962501 Down 0.118385423 Gm10696 predicted gene 10696 K10523|1|1e-121|440|cge:100763306|speckle-type POZ protein - - - gi|225735602|ref|NP_001139579.1|/0/TD and POZ domain containing-like [Mus musculus] 75721 3643 0.033333333 0.01 -1.736965594 Down 0.118385423 4932414N04Rik RIKEN cDNA 4932414N04 gene K17299|1|2e-17|94.4|shr:100920140|POTE ankyrin domain family protein;K10421|5|4e-07|60.5|acs:100566771|CAP-Gly domain-containing linker protein 1 - - - "gi|148695076|gb|EDL27023.1|/0/RIKEN cDNA 4932414N04, partial [Mus musculus]" 545291 2175 0.01 0.03 1.584962501 Up 0.118385423 Hpse2 heparanase 2 K07965|1|0.0|1087|mmu:545291|heparanase 2 [EC:3.2.1.-] - - - - 13394 1820 0.01 0.033333333 1.736965594 Up 0.118385423 Dlx4 distal-less homeobox 4 K09314|1|4e-112|407|mmu:13394|homeobox protein DLX1/4/6 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|74203119|dbj|BAE26247.1|/3.50185e-111/unnamed protein product [Mus musculus] 100043072 1851 0.033333333 0.01 -1.736965594 Down 0.118385423 A230070E04Rik RIKEN cDNA A230070E04 gene K04573|1|2e-158|561|mmu:18040|neurofilament medium polypeptide (neurofilament 3) - - - - 18377 2226 0.03 0.01 -1.584962501 Down 0.118385423 Omg oligodendrocyte myelin glycoprotein K16666|1|0.0|822|mmu:18377|oligodendrocyte myelin glycoprotein GO:0031224//intrinsic component of membrane;GO:0044464 GO:0042802//identical protein binding GO:0022610;GO:0033554//cellular response to stress;GO:0014003//oligodendrocyte development;GO:0048670//regulation of collateral sprouting gi|226874869|ref|NP_062282.2|/0/oligodendrocyte-myelin glycoprotein precursor [Mus musculus] 67373 2142 0.03 0.01 -1.584962501 Down 0.118385423 2210010C04Rik RIKEN cDNA 2210010C04 gene K01312|1|3e-140|501|mmu:67373|trypsin [EC:3.4.21.4] GO:0044421 GO:0004175//endopeptidase activity;GO:0043169//cation binding GO:0019538//protein metabolic process;GO:0044707 gi|71043961|ref|NP_075822.3|/2.17846e-139/trypsinogen 7 precursor [Mus musculus] 239849 1700 0.01 0.03 1.584962501 Up 0.118385423 Cd200r4 CD200 receptor 4 K06531|1|3e-11|72.8|xma:102231310|poliovirus receptor-related protein 2;K06592|4|2e-10|69.7|ola:101160012|poliovirus receptor-related protein 3 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0005488//binding - gi|46402237|ref|NP_997127.1|/5.75735e-153/cell surface glycoprotein CD200 receptor 4 precursor [Mus musculus] 442829 2030 0.03 0.01 -1.584962501 Down 0.118385423 Ccin calicin K10449|1|4e-43|179|sko:100375441|kelch-like protein 11;K10450|2|2e-35|153|bfo:BRAFLDRAFT_64963|kelch-like protein 12;K10443|4|1e-28|130|sko:102808558|kelch-like protein 2/3;K10461|5|4e-28|129|sko:100377360|kelch-like protein 24/35 GO:0033011//perinuclear theca - GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|50582595|ref|NP_001002787.1|/0/calicin [Mus musculus] 622474 2331 0.033333333 0.01 -1.736965594 Down 0.118385423 Smok3b sperm motility kinase 3B K08798|1|3e-143|511|cge:100775051|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|89941468|ref|NP_001034978.1|/0/sperm motility kinase 3 [Mus musculus] 73324 2152 0.01 0.03 1.584962501 Up 0.118385423 Clhc1 clathrin heavy chain linker domain containing 1 K04646|1|3e-11|73.2|crg:105340059|clathrin heavy chain - - - gi|254588118|ref|NP_001156993.1|/0/clathrin heavy chain linker domain-containing protein 1 isoform 2 [Mus musculus] 628877 2363 0.03 0.01 -1.584962501 Down 0.118385423 Gm29685 "predicted gene, 29685" - - - - - 432613 1932 0.033333333 0.01 -1.736965594 Down 0.118385423 Trim80 tripartite motif-containing 80 K12023|1|0.0|880|mdo:100027651|tripartite motif-containing protein 47;K12006|3|7e-70|267|lcm:102362819|tripartite motif-containing protein 16 - GO:0043169//cation binding - gi|85702085|ref|NP_001028947.1|/0/tripartite motif protein 47-like [Mus musculus] 226565 1870 0.01 0.03 1.584962501 Up 0.118385423 Fmo6 flavin containing monooxygenase 6 K00485|1|0.0|1038|mmu:226565|dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8] - - - gi|295842425|ref|NP_001171509.1|/0/flavin containing monooxygenase 6 [Mus musculus] 93877 2319 0.03 0.01 -1.584962501 Down 0.118385423 Pcdhb6 protocadherin beta 6 K16494|1|0.0|1453|mmu:93877|protocadherin beta - - - - 384619 2210 0.01 0.03 1.584962501 Up 0.118385423 Ccdc155 coiled-coil domain containing 155 "K12337|1|3e-10|69.7|cmk:103189090|inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate;K16469|2|6e-10|68.9|cmk:103187449|rootletin;K20478|4|2e-09|67.4|sko:100376626|golgin subfamily B member 1" GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding;GO:0004721//phosphoprotein phosphatase activity GO:0006464//cellular protein modification process gi|237512934|ref|NP_958762.2|/0/protein KASH5 [Mus musculus] 67935 1893 0.01 0.033333333 1.736965594 Up 0.118385423 Ces5a carboxylesterase 5A K15743|1|0.0|1063|mmu:67935|carboxylesterase 3/5 [EC:3.1.1.1] - - - gi|51556221|ref|NP_001003951.1|/0/carboxylesterase 5A precursor [Mus musculus] 320038 4247 0.01 0.033333333 1.736965594 Up 0.118385423 Dlx6os1 "distal-less homeobox 6, opposite strand 1" - - - - - 234669 1912 0.01 0.03 1.584962501 Up 0.118385423 Ces2b carboxyesterase 2B K03927|1|0.0|1108|mmu:234669|carboxylesterase 2 [EC:3.1.1.1 3.1.1.84 3.1.1.56] GO:0043227//membrane-bounded organelle GO:0052689//carboxylic ester hydrolase activity - gi|37718991|ref|NP_937814.1|/0/carboxyesterase 2B precursor [Mus musculus] 329639 1805 0.01 0.033333333 1.736965594 Up 0.118385423 Gm2447 predicted gene 2447 - - - - "gi|148703281|gb|EDL35228.1|/2.19478e-73/mCG125822, isoform CRA_c [Mus musculus]" 58227 4136 0.03 0.01 -1.584962501 Down 0.118385423 Fam184b "family with sequence similarity 184, member B" K16808|1|3e-20|103|pale:102891874|nuclear mitotic apparatus protein 1 - - - gi|188219653|ref|NP_067391.3|/0/protein FAM184B [Mus musculus] 332934 1505 0.01 0.033333333 1.736965594 Up 0.118385423 Zmynd12 "zinc finger, MYND domain containing 12" - - GO:0046914//transition metal ion binding - gi|225543354|ref|NP_001014900.2|/0/zinc finger MYND domain-containing protein 12 [Mus musculus] 100038859 948 0.033333333 0.01 -1.736965594 Down 0.118385423 Olfr55 olfactory receptor 55 K04257|1|5e-156|552|mmu:100038859|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007154//cell communication gi|154091001|ref|NP_035128.2|/4.47651e-155/olfactory receptor 55 [Mus musculus] 12425 2929 0.01 0.033333333 1.736965594 Up 0.118385423 Cckar cholecystokinin A receptor K04194|1|0.0|747|rno:24889|cholecystokinin A receptor GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0033267 GO:0008188//neuropeptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0090273//regulation of somatostatin secretion;GO:0007589//body fluid secretion;GO:0006816//calcium ion transport;GO:0030036//actin cytoskeleton organization;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007420//brain development;GO:0009628//response to abiotic stimulus;GO:0002021//response to dietary excess;GO:0009887//organ morphogenesis;GO:0031960//response to corticosteroid;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0006813//potassium ion transport;GO:0002237//response to molecule of bacterial origin;GO:0022600//digestive system process;GO:0016477//cell migration;GO:0031667//response to nutrient levels gi|672076328|ref|XP_008768410.1|/0/PREDICTED: cholecystokinin receptor type A isoform X1 [Rattus norvegicus] 17075 2061 0.03 0.01 -1.584962501 Down 0.118385423 Epcam epithelial cell adhesion molecule K06737|1|3e-153|544|mmu:17075|tumor-associated calcium signal transducer 1 GO:0043296//apical junction complex;GO:0044459;GO:0031224//intrinsic component of membrane - GO:0035295//tube development;GO:0008283//cell proliferation "gi|148706687|gb|EDL38634.1|/2.80297e-152/tumor-associated calcium signal transducer 1, partial [Mus musculus]" 625321 1890 0.033333333 0.01 -1.736965594 Down 0.118385423 Trim30e-ps1 "tripartite motif-containing 30E, pseudogene 1" K10648|1|3e-83|269|mmu:209387|tripartite motif-containing protein 5 [EC:2.3.2.27] - - - - 76728 1631 0.01 0.033333333 1.736965594 Up 0.118385423 1700123J17Rik RIKEN cDNA 1700123J17 gene - - - - - 75288 1881 0.01 0.03 1.584962501 Up 0.118385423 Slc35f4 "solute carrier family 35, member F4" "K15288|1|0.0|858|mmu:75288|solute carrier family 35, member F3/4" GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization gi|58037407|ref|NP_083514.1|/0/solute carrier family 35 member F4 [Mus musculus] 14403 1896 0.01 0.033333333 1.736965594 Up 0.118385423 Gabrd "gamma-aminobutyric acid (GABA) A receptor, subunit delta" K05184|1|0.0|754|mmu:14403|gamma-aminobutyric acid receptor subunit delta GO:0034702//ion channel complex;GO:0097060//synaptic membrane GO:0015276//ligand-gated ion channel activity;GO:0005253//anion channel activity GO:0015698//inorganic anion transport;GO:0007267//cell-cell signaling gi|160707923|ref|NP_032098.2|/0/gamma-aminobutyric acid receptor subunit delta precursor [Mus musculus] 215095 2261 0.03 0.01 -1.584962501 Down 0.118385423 Astl astacin-like metalloendopeptidase (M12 family) K08778|1|0.0|814|mmu:215095|astacin-like metalloendopeptidase [EC:3.4.-.-] - - - - 328643 4548 0.03 0.01 -1.584962501 Down 0.118385423 Vwa5b2 von Willebrand factor A domain containing 5B2 K10798|1|1e-12|77.8|aqu:100633591|poly [ADP-ribose] polymerase [EC:2.4.2.30];K18466|2|3e-08|63.2|smm:Smp_073130.1|vacuolar protein sorting-associated protein 26 - - - gi|222352132|ref|NP_001138425.1|/0/von Willebrand factor A domain-containing protein 5B2 isoform 1 [Mus musculus] 58866 1943 0.033333333 0.01 -1.736965594 Down 0.118385423 Treh trehalase (brush-border membrane glycoprotein) "K01194|1|0.0|1125|mmu:58866|alpha,alpha-trehalase [EC:3.2.1.28]" GO:0031224//intrinsic component of membrane;GO:0042995//cell projection;GO:0031224//intrinsic component of membrane;GO:0042995//cell projection;GO:0031224//intrinsic component of membrane;GO:0042995//cell projection GO:0015927//trehalase activity;GO:0015927//trehalase activity;GO:0015927//trehalase activity GO:0009653//anatomical structure morphogenesis;GO:0005984//disaccharide metabolic process;GO:0009653//anatomical structure morphogenesis;GO:0005984//disaccharide metabolic process;GO:0009653//anatomical structure morphogenesis;GO:0005984//disaccharide metabolic process "gi|148693662|gb|EDL25609.1|/0/trehalase (brush-border membrane glycoprotein), isoform CRA_b, partial [Mus musculus]" 433485 2073 0.03 0.01 -1.584962501 Down 0.118385423 Syndig1 synapse differentiation inducing 1 - GO:0016021//integral component of membrane;GO:0005769//early endosome;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0012505//endomembrane system GO:0042802//identical protein binding;GO:0005102//receptor binding GO:0050896//response to stimulus;GO:0007416//synapse assembly;GO:0097090//presynaptic membrane organization;GO:0015031//protein transport gi|147903397|ref|NP_001078990.1|/5.1822e-130/synapse differentiation-inducing gene protein 1 [Mus musculus] 231832 1859 0.033333333 0.01 -1.736965594 Down 0.118385423 Tmem184a transmembrane protein 184a K14360|1|4e-12|75.9|sko:100372211|organic solute transporter subunit alpha GO:0005769//early endosome;GO:0031224//intrinsic component of membrane;GO:0005769//early endosome;GO:0031224//intrinsic component of membrane - GO:0008104//protein localization;GO:0046903//secretion;GO:0007275//multicellular organism development;GO:0008104//protein localization;GO:0046903//secretion;GO:0007275//multicellular organism development gi|238859633|ref|NP_001155020.1|/0/transmembrane protein 184A isoform 1 [Mus musculus] 114479 2943 0.01 0.033333333 1.736965594 Up 0.118385423 Slc5a5 "solute carrier family 5 (sodium iodide symporter), member 5" "K14385|1|0.0|1181|mmu:114479|solute carrier family 5 (sodium/iodide cotransporter), member 5" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0015103//inorganic anion transmembrane transporter activity;GO:0015373 GO:0006814//sodium ion transport;GO:0015698//inorganic anion transport;GO:0032870//cellular response to hormone stimulus;GO:0042403//thyroid hormone metabolic process;GO:0051591//response to cAMP gi|162138897|ref|NP_444478.2|/0/sodium/iodide cotransporter [Mus musculus] 30051 1824 0.033333333 0.01 -1.736965594 Down 0.118385423 Spdef SAM pointed domain containing ets transcription factor K09442|1|0.0|681|mmu:30051|SAM pointed domain-containing ETS transcription factor GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0010453//regulation of cell fate commitment;GO:0002066//columnar/cuboidal epithelial cell development;GO:0006915//apoptotic process;GO:0060481//lobar bronchus epithelium development "gi|148690600|gb|EDL22547.1|/0/SAM pointed domain containing ets transcription factor, isoform CRA_a, partial [Mus musculus]" 20997 2046 0.03 0.01 -1.584962501 Down 0.118385423 T brachyury K10172|1|0.0|882|mmu:20997|brachyury protein GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle "GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding" GO:0001501//skeletal system development;GO:0007338//single fertilization;GO:0014020;GO:0048568//embryonic organ development;GO:0001840//neural plate development;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0016055//Wnt signaling pathway;GO:0003256//regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0008283//cell proliferation;GO:0000578//embryonic axis specification;GO:0009887//organ morphogenesis;GO:0007368//determination of left/right symmetry;GO:0009952//anterior/posterior pattern specification;GO:0001707//mesoderm formation gi|6678203|ref|NP_033335.1|/0/brachyury protein [Mus musculus] 58176 1912 0.033333333 0.01 -1.736965594 Down 0.118385423 Rhbg Rhesus blood group-associated B glycoprotein K06580|1|0.0|662|mmu:58176|ammonium transporter Rh GO:0005856//cytoskeleton;GO:0016021//integral component of membrane;GO:0044459;GO:0031982//vesicle;GO:0031225//anchored component of membrane GO:0008092//cytoskeletal protein binding;GO:0008509//anion transmembrane transporter activity GO:0044763;GO:0015696//ammonium transport gi|31981136|ref|NP_067350.2|/0/ammonium transporter Rh type B precursor [Mus musculus] 11876 1837 0.033333333 0.01 -1.736965594 Down 0.118385423 Artn artemin K05452|1|7e-10|68.6|tru:101076675|glial cell derived neurotrophic factor GO:0044421;GO:0044421;GO:0044421 GO:0070851//growth factor receptor binding;GO:0070851//growth factor receptor binding;GO:0070851//growth factor receptor binding GO:0050927//positive regulation of positive chemotaxis;GO:0007399//nervous system development;GO:0072676//lymphocyte migration;GO:0009653//anatomical structure morphogenesis;GO:0050927//positive regulation of positive chemotaxis;GO:0007399//nervous system development;GO:0072676//lymphocyte migration;GO:0009653//anatomical structure morphogenesis;GO:0050927//positive regulation of positive chemotaxis;GO:0007399//nervous system development;GO:0072676//lymphocyte migration;GO:0009653//anatomical structure morphogenesis gi|545746341|ref|NP_001271121.1|/9.43277e-94/artemin isoform 2 precursor [Mus musculus] 12023 1791 0.01 0.033333333 1.736965594 Up 0.118385423 Barx2 BarH-like homeobox 2 K09361|1|1e-132|476|mmu:12023|BarH-like homeobox GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0016337//single organismal cell-cell adhesion;GO:0035914//skeletal muscle cell differentiation;GO:0022405//hair cycle process "gi|148693402|gb|EDL25349.1|/4.8779e-158/BarH-like homeobox 2, isoform CRA_a, partial [Mus musculus]" 15450 1779 0.01 0.033333333 1.736965594 Up 0.118385423 Lipc "lipase, hepatic" K01046|1|0.0|1046|mmu:15450|triacylglycerol lipase [EC:3.1.1.3] GO:0034358//plasma lipoprotein particle;GO:0005768//endosome;GO:0042995//cell projection;GO:0034358//plasma lipoprotein particle;GO:0005768//endosome;GO:0042995//cell projection;GO:0034358//plasma lipoprotein particle;GO:0005768//endosome;GO:0042995//cell projection GO:0005515//protein binding;GO:0004620//phospholipase activity;GO:0016740//transferase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0071813//lipoprotein particle binding;GO:0043168//anion binding;GO:0005539//glycosaminoglycan binding;GO:0005515//protein binding;GO:0004620//phospholipase activity;GO:0016740//transferase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0071813//lipoprotein particle binding;GO:0043168//anion binding;GO:0005539//glycosaminoglycan binding;GO:0005515//protein binding;GO:0004620//phospholipase activity;GO:0016740//transferase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0071813//lipoprotein particle binding;GO:0043168//anion binding;GO:0005539//glycosaminoglycan binding GO:0034370//triglyceride-rich lipoprotein particle remodeling;GO:0048511//rhythmic process;GO:0016125//sterol metabolic process;GO:0006575//cellular modified amino acid metabolic process;GO:0040007//growth;GO:0006461//protein complex assembly;GO:0055090//acylglycerol homeostasis;GO:0006650//glycerophospholipid metabolic process;GO:0016070//RNA metabolic process;GO:0006631//fatty acid metabolic process;GO:0010038//response to metal ion;GO:0001101//response to acid chemical;GO:0071830;GO:0031960//response to corticosteroid;GO:0009991//response to extracellular stimulus;GO:0044767//single-organism developmental process;GO:0006641//triglyceride metabolic process;GO:0030166//proteoglycan biosynthetic process;GO:0055092//sterol homeostasis;GO:0015918//sterol transport;GO:0034370//triglyceride-rich lipoprotein particle remodeling;GO:0048511//rhythmic process;GO:0016125//sterol metabolic process;GO:0006575//cellular modified amino acid metabolic process;GO:0040007//growth;GO:0006461//protein complex assembly;GO:0055090//acylglycerol homeostasis;GO:0006650//glycerophospholipid metabolic process;GO:0016070//RNA metabolic process;GO:0006631//fatty acid metabolic process;GO:0010038//response to metal ion;GO:0001101//response to acid chemical;GO:0071830;GO:0031960//response to corticosteroid;GO:0009991//response to extracellular stimulus;GO:0044767//single-organism developmental process;GO:0006641//triglyceride metabolic process;GO:0030166//proteoglycan biosynthetic process;GO:0055092//sterol homeostasis;GO:0015918//sterol transport;GO:0034370//triglyceride-rich lipoprotein particle remodeling;GO:0048511//rhythmic process;GO:0016125//sterol metabolic process;GO:0006575//cellular modified amino acid metabolic process;GO:0040007//growth;GO:0006461//protein complex assembly;GO:0055090//acylglycerol homeostasis;GO:0006650//glycerophospholipid metabolic process;GO:0016070//RNA metabolic process;GO:0006631//fatty acid metabolic process;GO:0010038//response to metal ion;GO:0001101//response to acid chemical;GO:0071830;GO:0031960//response to corticosteroid;GO:0009991//response to extracellular stimulus;GO:0044767//single-organism developmental process;GO:0006641//triglyceride metabolic process;GO:0030166//proteoglycan biosynthetic process;GO:0055092//sterol homeostasis;GO:0015918//sterol transport gi|31982278|ref|NP_032306.2|/0/hepatic triacylglycerol lipase precursor [Mus musculus] 625243 2107 0.01 0.03 1.584962501 Up 0.118385423 Gm6567 predicted gene 6567 - - - - - 212989 1971 0.03 0.01 -1.584962501 Down 0.118385423 Best2 bestrophin 2 K13879|1|0.0|832|mmu:212989|bestrophin-2 GO:0043231//intracellular membrane-bounded organelle;GO:0034702//ion channel complex;GO:0043231//intracellular membrane-bounded organelle;GO:0034702//ion channel complex GO:0005253//anion channel activity;GO:0005253//anion channel activity GO:0015698//inorganic anion transport;GO:0007606//sensory perception of chemical stimulus;GO:0042391//regulation of membrane potential;GO:0015698//inorganic anion transport;GO:0007606//sensory perception of chemical stimulus;GO:0042391//regulation of membrane potential "gi|148679037|gb|EDL10984.1|/0/vitelliform macular dystrophy 2-like protein 1, isoform CRA_b, partial [Mus musculus]" 67537 1879 0.033333333 0.01 -1.736965594 Down 0.118385423 Glipr1l2 GLI pathogenesis-related 1 like 2 K19919|1|1e-25|120|bfo:BRAFLDRAFT_90683|cysteine-rich secretory protein;K20412|2|4e-25|119|nle:100600537|peptidase inhibitor 16 GO:0031224//intrinsic component of membrane - - gi|74148291|dbj|BAE36300.1|/1.41405e-163/unnamed protein product [Mus musculus] 226243 2119 0.01 0.03 1.584962501 Up 0.118385423 Habp2 hyaluronic acid binding protein 2 K08648|1|0.0|1111|mmu:226243|hyaluronan binding protein 2 [EC:3.4.21.-] - GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|22122613|ref|NP_666213.1|/0/hyaluronan-binding protein 2 precursor [Mus musculus] 14378 1846 0.033333333 0.01 -1.736965594 Down 0.118385423 G6pc2 "glucose-6-phosphatase, catalytic, 2" K01084|1|0.0|710|mmu:14378|glucose-6-phosphatase [EC:3.1.3.9] - - - - 433374 1588 0.01 0.033333333 1.736965594 Up 0.118385423 Gm20743 "predicted gene, 20743" - - - - - 21943 2243 0.03 0.01 -1.584962501 Down 0.118385423 Tnfsf11 "tumor necrosis factor (ligand) superfamily, member 11" K05473|1|9e-168|593|mmu:21943|tumor necrosis factor ligand superfamily member 11 GO:0016021//integral component of membrane;GO:0044424;GO:0044421 GO:0032813//tumor necrosis factor receptor superfamily binding GO:0001894//tissue homeostasis;GO:0009628//response to abiotic stimulus;GO:0031622//positive regulation of fever generation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0050673//epithelial cell proliferation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0046887//positive regulation of hormone secretion;GO:0022409//positive regulation of cell-cell adhesion;GO:0055065//metal ion homeostasis;GO:0009653//anatomical structure morphogenesis;GO:0030595//leukocyte chemotaxis;GO:0007254//JNK cascade;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0070661//leukocyte proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0051259//protein oligomerization;GO:0000187//activation of MAPK activity;GO:0042110//T cell activation gi|114842415|ref|NP_035743.2|/7.61896e-167/tumor necrosis factor ligand superfamily member 11 [Mus musculus] 77596 3504 0.033333333 0.01 -1.736965594 Down 0.118385423 Adgrf1 adhesion G protein-coupled receptor F1 K08453|1|0.0|1550|mmu:77596|G protein-coupled receptor 110 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007186//G-protein coupled receptor signaling pathway gi|569002046|ref|XP_006525183.1|/0/PREDICTED: G-protein coupled receptor 110 isoform X1 [Mus musculus] 241589 10124 0.03 0.01 -1.584962501 Down 0.118385423 D430041D05Rik RIKEN cDNA D430041D05 gene - - - - gi|124358961|ref|NP_001028519.2|/0/UPF0606 protein KIAA1549L homolog [Mus musculus] 432436 2206 0.01 0.03 1.584962501 Up 0.118385423 Gm5420 predicted gene 5420 - - - - "gi|148671464|gb|EDL03411.1|/3.82753e-54/hypothetical protein LOC432436, partial [Mus musculus]" 272643 1995 0.01 0.03 1.584962501 Up 0.118385423 Prss43 "protease, serine 43" K09628|1|2e-41|172|pbi:103054953|serine protease 27 [EC:3.4.21.-];K08664|2|2e-41|172|acs:100551951|prostasin [EC:3.4.21.-];K09625|3|2e-40|170|ggo:101149961|testisin [EC:3.4.21.-];K09634|4|2e-40|169|xtr:100490444|transmembrane protease serine 3 [EC:3.4.21.-] - - - "gi|41054966|ref|NP_955765.1|/0/protease, serine 43 precursor [Mus musculus]" 381538 4346 0.03 0.01 -1.584962501 Down 0.118385423 Mroh7 maestro heat-like repeat family member 7 K09093|1|1e-08|65.5|clv:102095043|aryl hydrocarbon receptor;K10770|2|2e-07|62.0|nle:100604945|alkylated DNA repair protein alkB homolog 8 [EC:1.14.11.- 2.1.1.229] GO:0031224//intrinsic component of membrane - - gi|187608579|ref|NP_001119959.1|/0/maestro heat-like repeat-containing protein family member 7 [Mus musculus] 76627 1876 0.01 0.03 1.584962501 Up 0.118385423 Prr30 proline rich 30 - - - - gi|147906142|ref|NP_083956.1|/0/proline-rich protein 30 [Mus musculus] 14608 3460 0.01 0.03 1.584962501 Up 0.118385423 Gpr83 G protein-coupled receptor 83 K04210|1|0.0|763|mmu:14608|G protein-coupled receptor 83 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0008188//neuropeptide receptor activity;GO:0008188//neuropeptide receptor activity GO:0031960//response to corticosteroid;GO:0007166//cell surface receptor signaling pathway;GO:0031960//response to corticosteroid;GO:0007166//cell surface receptor signaling pathway gi|6753988|ref|NP_034417.1|/0/probable G-protein coupled receptor 83 isoform 1 precursor [Mus musculus] 105418 1492 0.01 0.033333333 1.736965594 Up 0.118385423 E330034G19Rik RIKEN cDNA E330034G19 gene "K03844|1|4e-16|88.6|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131];K06267|3|1e-07|60.5|oaa:100079090|hyaluronan-mediated motility receptor;K16540|4|2e-07|60.1|tca:661736|5-azacytidine-induced protein 1;K09228|5|2e-06|56.2|fca:105261299|KRAB domain-containing zinc finger protein" - - - - 100039953 1877 0.01 0.033333333 1.736965594 Up 0.118385423 Gfy golgi-associated olfactory signaling regulator K10955|1|2e-13|80.1|myb:102241796|intestinal mucin-2 - - - - 74363 2166 0.01 0.03 1.584962501 Up 0.118385423 4931430N09Rik RIKEN cDNA 4931430N09 gene - - - - "gi|148667189|gb|EDK99605.1|/8.54814e-83/mCG1037092, partial [Mus musculus]" 12647 2810 0.033333333 0.01 -1.736965594 Down 0.118385423 Chat choline acetyltransferase K00623|1|0.0|1243|mmu:12647|choline O-acetyltransferase [EC:2.3.1.6] GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0044297//cell body;GO:0005737//cytoplasm GO:0043169//cation binding;GO:0016413//O-acetyltransferase activity GO:0008344//adult locomotory behavior;GO:0007528//neuromuscular junction development;GO:0007611//learning or memory;GO:0031175//neuron projection development;GO:0060024//rhythmic synaptic transmission;GO:0042136//neurotransmitter biosynthetic process gi|45476575|ref|NP_034021.1|/0/choline O-acetyltransferase [Mus musculus] 546024 2138 0.01 0.03 1.584962501 Up 0.118385423 Crxos "cone-rod homeobox, opposite strand" K18491|1|4e-06|45.1|pon:100443010|homeobox protein ESX1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|74138274|dbj|BAE28773.1|/8.09114e-92/unnamed protein product [Mus musculus] 320272 2212 0.01 0.03 1.584962501 Up 0.118385423 9330162B11Rik RIKEN cDNA 9330162B11 gene - - - - "gi|148681095|gb|EDL13042.1|/1.67368e-41/mCG1029224, partial [Mus musculus]" 209837 1878 0.01 0.033333333 1.736965594 Up 0.118385423 Slc38a5 "solute carrier family 38, member 5" "K14992|1|0.0|761|mmu:209837|solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 5" - - - - 790912 2187 0.01 0.03 1.584962501 Up 0.118385423 Rab11fip4os1 "RAB11 family interacting protein 4 (class II), opposite strand 1" - - - - - 69706 1501 0.01 0.033333333 1.736965594 Up 0.118385423 Lrr1 leucine rich repeat protein 1 K10348|1|0.0|796|mmu:69706|LRR-repeat protein 1 - - - "gi|148704681|gb|EDL36628.1|/0/mCG7609, isoform CRA_b, partial [Mus musculus]" 14802 2338 0.03 0.01 -1.584962501 Down 0.118385423 Gria4 "glutamate receptor, ionotropic, AMPA4 (alpha 4)" K05200|1|0.0|1758|pale:102887651|glutamate receptor 4 GO:0044297//cell body;GO:0033267;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0008328//ionotropic glutamate receptor complex;GO:0044297//cell body;GO:0033267;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0008328//ionotropic glutamate receptor complex;GO:0044297//cell body;GO:0033267;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0008328//ionotropic glutamate receptor complex GO:0005488//binding;GO:0004970//ionotropic glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0005488//binding;GO:0004970//ionotropic glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0005488//binding;GO:0004970//ionotropic glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity "GO:0009636//response to toxic substance;GO:0035249//synaptic transmission, glutamatergic;GO:0007215//glutamate receptor signaling pathway;GO:0044765//single-organism transport;GO:0009636//response to toxic substance;GO:0035249//synaptic transmission, glutamatergic;GO:0007215//glutamate receptor signaling pathway;GO:0044765//single-organism transport;GO:0009636//response to toxic substance;GO:0035249//synaptic transmission, glutamatergic;GO:0007215//glutamate receptor signaling pathway" gi|940757567|ref|XP_006098893.2|/0/PREDICTED: glutamate receptor 4 isoform X1 [Myotis lucifugus] 78919 2081 0.01 0.03 1.584962501 Up 0.118385423 Fndc8 fibronectin type III domain containing 8 K12018|1|8e-11|71.6|lcm:102350171|tripartite motif-containing protein 42 - - - gi|113931164|ref|NP_084500.1|/4.36046e-169/fibronectin type III domain-containing protein 8 [Mus musculus] 381417 3740 0.033333333 0.01 -1.736965594 Down 0.118385423 Gm14085 predicted gene 14085 K11536|1|0.0|1142|mmu:269346|pyrimidine nucleoside transport protein GO:0031224//intrinsic component of membrane GO:0036094//small molecule binding;GO:0005337//nucleoside transmembrane transporter activity GO:0072530//purine-containing compound transmembrane transport;GO:0001894//tissue homeostasis;GO:0034613//cellular protein localization "gi|147901770|ref|NP_001078987.1|/0/solute carrier family 28 (sodium-coupled nucleoside transporter), member 2-like [Mus musculus] " 11657 2076 0.03 0.01 -1.584962501 Down 0.118385423 Alb albumin K16141|1|0.0|1256|mmu:11657|serum albumin - - - - 328505 1802 0.01 0.033333333 1.736965594 Up 0.118385423 Skint7 selection and upkeep of intraepithelial T cells 7 K06712|1|6e-71|271|myd:102760529|butyrophilin GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|218505807|ref|NP_001136247.1|/0/selection and upkeep of intraepithelial T-cells protein 7 isoform 1 precursor [Mus musculus] 228094 1759 0.033333333 0.01 -1.736965594 Down 0.118385423 Cerkl ceramide kinase-like K19602|1|0.0|957|mmu:228094|ceramide kinase-like protein - - - - 241850 1775 0.01 0.03 1.584962501 Up 0.118385423 Abhd16b abhydrolase domain containing 16B - - GO:0003824//catalytic activity - gi|34147236|ref|NP_899004.1|/0/protein ABHD16B [Mus musculus] 626410 1827 0.033333333 0.01 -1.736965594 Down 0.118385423 Gm20755 "predicted gene, 20755" - - - - "gi|148703177|gb|EDL35124.1|/1.77411e-54/mCG145533, partial [Mus musculus]" 22625 3936 0.03 0.01 -1.584962501 Down 0.118385423 Map3k19 mitogen-activated protein kinase kinase kinase 19 K17533|1|0.0|2560|mmu:22625|mitogen-activated protein kinase kinase kinase 19 [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|568908673|ref|XP_006529459.1|/0/PREDICTED: mitogen-activated protein kinase kinase kinase 19 isoform X1 [Mus musculus] 380728 3784 0.01 0.03 1.584962501 Up 0.118385423 Kcnh4 "potassium voltage-gated channel, subfamily H (eag-related), member 4" K04907|1|0.0|1791|mmu:380728|potassium voltage-gated channel Eag-related subfamily H member 4 GO:0031224//intrinsic component of membrane GO:0004673//protein histidine kinase activity;GO:0005267//potassium channel activity "GO:0044765//single-organism transport;GO:0006351//transcription, DNA-templated" gi|124487121|ref|NP_001074663.1|/0/potassium voltage-gated channel subfamily H member 4 [Mus musculus] 15377 2039 0.03 0.01 -1.584962501 Down 0.118385423 Foxa3 forkhead box A3 "K08038|1|8e-155|550|mmu:15377|forkhead box protein A3, hepatocyte nuclear factor 3-gamma" - - - gi|6679831|ref|NP_032286.1|/6.58457e-154/hepatocyte nuclear factor 3-gamma [Mus musculus] 100418235 2163 0.01 0.03 1.584962501 Up 0.118385423 C130030K03Rik "proteasome (prosome, macropain) subunit, alpha type 6 pseudogene" K02730|1|8e-58|102|xla:495277|20S proteasome subunit alpha 1 [EC:3.4.25.1] GO:0034399//nuclear periphery;GO:0005839//proteasome core complex;GO:0030016//myofibril;GO:0030529//intracellular ribonucleoprotein complex "GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0003676//nucleic acid binding;GO:0008134//transcription factor binding" "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0014706//striated muscle tissue development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0044764;GO:0051320;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0006954//inflammatory response;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|403263938|ref|XP_003924255.1|/2.81508e-58/PREDICTED: proteasome subunit alpha type-6 [Saimiri boliviensis boliviensis] 71522 1841 0.01 0.033333333 1.736965594 Up 0.118385423 Ggt6 gamma-glutamyltransferase 6 K00681|1|0.0|678|mmu:71522|gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] - GO:0016740//transferase activity - gi|117647222|ref|NP_082095.2|/0/gamma-glutamyltransferase 6 [Mus musculus] 53626 3038 0.01 0.03 1.584962501 Up 0.118385423 Insm1 insulinoma-associated 1 K09228|1|3e-08|63.5|ptg:102953474|KRAB domain-containing zinc finger protein;K09229|3|3e-07|60.5|nle:100598957|KRAB and SCAN domains-containing zinc finger protein GO:0031981//nuclear lumen GO:0005488//binding GO:0035270//endocrine system development;GO:0048869//cellular developmental process;GO:0031016//pancreas development gi|70778863|ref|NP_058585.2|/0/insulinoma-associated protein 1 [Mus musculus] 625342 1981 0.03 0.01 -1.584962501 Down 0.118385423 Gm13315 lactate dehydrogenase A pseudogene K00016|1|8e-141|321|mmu:16828|L-lactate dehydrogenase [EC:1.1.1.27] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0004457//lactate dehydrogenase activity;GO:0019899//enzyme binding;GO:0000166//nucleotide binding GO:0006007//glucose catabolic process;GO:0006915//apoptotic process;GO:0032787//monocarboxylic acid metabolic process;GO:0046496//nicotinamide nucleotide metabolic process;GO:0007154//cell communication gi|257743039|ref|NP_001129541.2|/1.86772e-142/L-lactate dehydrogenase A chain isoform 2 [Mus musculus] 17940 5361 0.01 0.033333333 1.736965594 Up 0.118385423 Naip1 "NLR family, apoptosis inhibitory protein 1" K12807|1|0.0|2764|mmu:17940|baculoviral IAP repeat-containing protein 1 GO:0043234//protein complex;GO:0044459;GO:0044424 GO:0043169//cation binding;GO:0032550;GO:0016462//pyrophosphatase activity;GO:0004869//cysteine-type endopeptidase inhibitor activity GO:0043627//response to estrogen;GO:0042742//defense response to bacterium;GO:0006915//apoptotic process;GO:0051346//negative regulation of hydrolase activity;GO:0009581 gi|114431262|ref|NP_032696.2|/0/baculoviral IAP repeat-containing protein 1a [Mus musculus] 117586 1823 0.033333333 0.01 -1.736965594 Down 0.118385423 A1bg alpha-1-B glycoprotein K06512|1|2e-25|120|myb:102262946|leukocyte immunoglobulin-like receptor - - - - 380684 4004 0.03 0.01 -1.584962501 Down 0.118385423 Nefh "neurofilament, heavy polypeptide" K04574|1|0.0|1260|mmu:380684|neurofilament heavy polypeptide - - - gi|124286811|ref|NP_035034.2|/0/neurofilament heavy polypeptide [Mus musculus] 20957 3437 0.01 0.03 1.584962501 Up 0.118385423 Sycp1 synaptonemal complex protein 1 K19533|1|0.0|1707|mmu:20957|synaptonemal complex protein 1 GO:0043073//germ cell nucleus;GO:0000795//synaptonemal complex GO:0003676//nucleic acid binding GO:0008104//protein localization;GO:0007129//synapsis "gi|735904|gb|AAA64514.1|/0/testicular protein, partial [Mus musculus]" 72082 1989 0.01 0.03 1.584962501 Up 0.118385423 Cyp2c55 "cytochrome P450, family 2, subfamily c, polypeptide 55" "K07413|1|0.0|964|mmu:72082|cytochrome P450, family 2, subfamily C [EC:1.14.14.1];K17720|5|0.0|778|mcc:701855|cytochrome P450, family 2, subfamily C, polypeptide 18 [EC:1.14.14.1]" GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0033695;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0008395//steroid hydroxylase activity" GO:0019752//carboxylic acid metabolic process;GO:0055114//oxidation-reduction process;GO:0043603//cellular amide metabolic process;GO:0006721//terpenoid metabolic process;GO:0042493//response to drug;GO:0017144//drug metabolic process gi|13386282|ref|NP_082365.1|/0/cytochrome P450 2C55 precursor [Mus musculus] 230558 3542 0.01 0.03 1.584962501 Up 0.118385423 C8a "complement component 8, alpha polypeptide" K03997|1|0.0|1222|mmu:230558|complement component 8 subunit alpha - - - - 219170 2238 0.03 0.01 -1.584962501 Down 0.118385423 Fam216b "family with sequence similarity 216, member B" - - - - gi|29244020|ref|NP_808297.1|/8.34185e-73/protein FAM216B [Mus musculus] 11440 2921 0.01 0.033333333 1.736965594 Up 0.118385423 Chrna6 "cholinergic receptor, nicotinic, alpha polypeptide 6" K04808|1|0.0|993|mmu:11440|nicotinic acetylcholine receptor alpha-6 GO:0097060//synaptic membrane;GO:0005887//integral component of plasma membrane GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0007267//cell-cell signaling;GO:0051259//protein oligomerization;GO:0006811//ion transport;GO:0010646//regulation of cell communication;GO:0042391//regulation of membrane potential gi|31542395|ref|NP_067344.2|/0/neuronal acetylcholine receptor subunit alpha-6 precursor [Mus musculus] 319951 1864 0.01 0.03 1.584962501 Up 0.118385423 A230001M10Rik RIKEN cDNA A230001M10 gene - - - - - 70086 1745 0.01 0.033333333 1.736965594 Up 0.118385423 Cysltr2 cysteinyl leukotriene receptor 2 K04323|1|3e-177|624|mmu:70086|cysteinyl leukotriene receptor 2 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004974//leukotriene receptor activity;GO:0004974//leukotriene receptor activity GO:0001525//angiogenesis;GO:0043410//positive regulation of MAPK cascade;GO:0008219//cell death;GO:0007166//cell surface receptor signaling pathway;GO:0001525//angiogenesis;GO:0043410//positive regulation of MAPK cascade;GO:0008219//cell death;GO:0007166//cell surface receptor signaling pathway gi|242397434|ref|NP_598481.2|/3.06833e-176/cysteinyl leukotriene receptor 2 [Mus musculus] 71830 2139 0.03 0.01 -1.584962501 Down 0.118385423 Pdilt "protein disulfide isomerase-like, testis expressed" K20354|1|0.0|1018|mmu:71830|protein disulfide-isomerase-like protein of the testis - - - - 71304 2075 0.03 0.01 -1.584962501 Down 0.118385423 Wbscr25 Williams Beuren syndrome chromosome region 25 (human) K03006|1|7e-13|78.6|fab:101818944|DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] - - - gi|29465660|gb|AAL91077.1|/1.40405e-151/Williams-Beuren syndrome critical region protein 25 [Mus musculus] 14262 2048 0.01 0.03 1.584962501 Up 0.118385423 Fmo3 flavin containing monooxygenase 3 K00485|1|0.0|1025|mmu:14262|dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8] - - - - 12740 1827 0.01 0.03 1.584962501 Up 0.118385423 Cldn4 claudin 4 K06087|1|1e-109|399|mmu:12740|claudin - - - - 242707 1954 0.01 0.03 1.584962501 Up 0.118385423 Lactbl1 "lactamase, beta-like 1" K00012|1|1e-17|94.4|bacu:103011302|UDPglucose 6-dehydrogenase [EC:1.1.1.22] - - - gi|343098431|ref|NP_001230191.1|/0/putative beta-lactamase-like 1 [Mus musculus] 110648 3338 0.033333333 0.01 -1.736965594 Down 0.118385423 Lmx1a LIM homeobox transcription factor 1 alpha K09371|1|0.0|718|mmu:110648|LIM homeobox transcription factor 1 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0022037//metencephalon development;GO:0006935//chemotaxis;GO:0021766//hippocampus development;GO:0006351//transcription, DNA-templated;GO:0030182//neuron differentiation" gi|17298670|ref|NP_387501.1|/0/LIM homeobox transcription factor 1-alpha [Mus musculus] 72000 2047 0.01 0.03 1.584962501 Up 0.118385423 Lmntd2 lamin tail domain containing 2 - - - - gi|113931154|ref|NP_082326.1|/0/lamin tail domain-containing protein 2 [Mus musculus] 13483 4531 0.01 0.033333333 1.736965594 Up 0.118385423 Dpp6 dipeptidylpeptidase 6 K01278|1|2e-131|473|bfo:BRAFLDRAFT_66877|dipeptidyl-peptidase 4 [EC:3.4.14.5] GO:0044297//cell body;GO:0005887//integral component of plasma membrane;GO:0044297//cell body;GO:0005887//integral component of plasma membrane;GO:0044297//cell body;GO:0005887//integral component of plasma membrane;GO:0044297//cell body;GO:0005887//integral component of plasma membrane "GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0008238//exopeptidase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0001508//action potential;GO:0006813//potassium ion transport;GO:0019538//protein metabolic process;GO:0001508//action potential;GO:0006813//potassium ion transport;GO:0019538//protein metabolic process;GO:0001508//action potential;GO:0006813//potassium ion transport;GO:0019538//protein metabolic process;GO:0001508//action potential;GO:0006813//potassium ion transport;GO:0019538//protein metabolic process gi|312032384|ref|NP_001185815.1|/0/dipeptidyl aminopeptidase-like protein 6 isoform 4 [Mus musculus] 100043092 1594 0.01 0.03 1.584962501 Up 0.118385423 Gm4224 predicted gene 4224 - - - - gi|148677539|gb|EDL09486.1|/3.13259e-12/mCG147332 [Mus musculus] 215446 3467 0.033333333 0.01 -1.736965594 Down 0.118385423 Entpd3 ectonucleoside triphosphate diphosphohydrolase 3 K01510|1|0.0|991|mmu:215446|apyrase [EC:3.6.1.5] GO:0016020//membrane GO:0008252//nucleotidase activity;GO:0016462//pyrophosphatase activity GO:0009141//nucleoside triphosphate metabolic process;GO:0009132//nucleoside diphosphate metabolic process gi|255683318|ref|NP_848791.2|/0/ectonucleoside triphosphate diphosphohydrolase 3 [Mus musculus] 330164 1838 0.01 0.03 1.584962501 Up 0.118385423 C130026L21Rik RIKEN cDNA C130026L21 gene - - - - - 75860 1496 0.01 0.033333333 1.736965594 Up 0.118385423 Tex26 testis expressed 26 - - - - "gi|148673919|gb|EDL05866.1|/7.76336e-159/mCG144571, partial [Mus musculus]" 100038860 948 0.033333333 0.01 -1.736965594 Down 0.118385423 Olfr239 olfactory receptor 239 K04257|1|5e-156|552|mmu:100038860|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007154//cell communication gi|255069790|ref|NP_997058.2|/4.47651e-155/olfactory receptor 239 [Mus musculus] 70894 1744 0.033333333 0.01 -1.736965594 Down 0.118385423 Efcab3 EF-hand calcium binding domain 3 K18626|1|2e-08|63.5|cmk:103191497|trichohyalin - GO:0046872//metal ion binding - gi|755539710|ref|XP_011247563.1|/0/PREDICTED: EF-hand calcium-binding domain-containing protein 3 isoform X2 [Mus musculus] 628416 2018 0.01 0.03 1.584962501 Up 0.118385423 Gm6878 predicted gene 6878 - - - - gi|85702332|ref|NP_001033020.1|/8.72563e-58/uncharacterized protein LOC628416 [Mus musculus] 14415 1605 0.01 0.033333333 1.736965594 Up 0.118385423 Gad1 glutamate decarboxylase 1 K01580|1|0.0|1191|mmu:14415|glutamate decarboxylase [EC:4.1.1.15] - - - - 13710 1940 0.01 0.03 1.584962501 Up 0.118385423 Elf3 E74-like factor 3 K09429|1|0.0|687|mmu:13710|E74-like factor 3 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0048771//tissue remodeling;GO:0006366//transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0043062//extracellular structure organization;GO:0006952//defense response;GO:0001701//in utero embryonic development;GO:0048771//tissue remodeling;GO:0006366//transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0043062//extracellular structure organization;GO:0006952//defense response;GO:0001701//in utero embryonic development gi|568908113|ref|XP_006529187.1|/0/PREDICTED: ETS-related transcription factor Elf-3 isoform X1 [Mus musculus] 244698 5261 0.01 0.03 1.584962501 Up 0.118385423 Hephl1 hephaestin-like 1 K14735|1|0.0|1298|ccw:104691273|hephaestin [EC:1.16.3.1] - - - gi|258679416|ref|NP_001158269.1|/0/hephaestin-like protein 1 precursor [Mus musculus] 414068 1661 0.01 0.03 1.584962501 Up 0.118385423 Bach2os "BTB and CNC homology 2, opposite strand" K09042|1|2e-38|163|rno:313125|transcription regulator BACH - - - gi|148673561|gb|EDL05508.1|/2.75229e-75/mCG1050952 [Mus musculus] 435145 1804 0.033333333 0.01 -1.736965594 Down 0.118385423 Shisa8 shisa family member 8 - - - - gi|333108269|ref|NP_001193950.1|/5.1637e-115/putative protein shisa-8 precursor [Mus musculus] 18096 1808 0.01 0.03 1.584962501 Up 0.118385423 Nkx6-1 NK6 homeobox 1 K08030|1|1e-101|372|rno:65193|homeobox protein Nkx-6.1 GO:0031981//nuclear lumen GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding GO:0007166//cell surface receptor signaling pathway;GO:0009732;GO:0006366//transcription from RNA polymerase II promoter;GO:0021520//spinal cord motor neuron cell fate specification;GO:0021521//ventral spinal cord interneuron specification;GO:0010720//positive regulation of cell development;GO:0050796//regulation of insulin secretion;GO:0034097//response to cytokine;GO:0014070//response to organic cyclic compound;GO:0044093;GO:0010001//glial cell differentiation;GO:0003323//type B pancreatic cell development;GO:0032870//cellular response to hormone stimulus "gi|148688314|gb|EDL20261.1|/1.23749e-100/NK6 transcription factor related, locus 1 (Drosophila), partial [Mus musculus]" 21869 2265 0.01 0.033333333 1.736965594 Up 0.118385423 Nkx2-1 NK2 homeobox 1 K09342|1|4e-116|421|mmu:21869|homeobox protein Nkx-2.1 GO:0031981//nuclear lumen;GO:0043234//protein complex "GO:0000975//regulatory region DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding" GO:0060487//lung epithelial cell differentiation;GO:0045137//development of primary sexual characteristics;GO:0045168//cell-cell signaling involved in cell fate commitment;GO:0021879//forebrain neuron differentiation;GO:0006796//phosphate-containing compound metabolic process;GO:0021987//cerebral cortex development;GO:0009653//anatomical structure morphogenesis;GO:0016477//cell migration;GO:0022601//menstrual cycle phase;GO:0021536//diencephalon development;GO:0035270//endocrine system development;GO:0006935//chemotaxis;GO:0044708//single-organism behavior;GO:0050794//regulation of cellular process;GO:0002237//response to molecule of bacterial origin;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0009953//dorsal/ventral pattern formation;GO:0006366//transcription from RNA polymerase II promoter;GO:0021895//cerebral cortex neuron differentiation;GO:0006972//hyperosmotic response;GO:0097305//response to alcohol gi|35505463|gb|AAH57607.1|/3.07367e-115/NK2 homeobox 1 [Mus musculus] 18566 1972 0.01 0.03 1.584962501 Up 0.118385423 Pdcd1 programmed cell death 1 K06744|1|4e-164|580|mmu:18566|programmed cell death protein 1 - - - - 70881 1838 0.01 0.03 1.584962501 Up 0.118385423 Nt5c1b "5'-nucleotidase, cytosolic IB" K01081|1|0.0|1092|mmu:70881|5'-nucleotidase [EC:3.1.3.5] GO:0044444//cytoplasmic part GO:0008252//nucleotidase activity;GO:0046872//metal ion binding;GO:0036094//small molecule binding GO:0006753//nucleoside phosphate metabolic process;GO:0046128 "gi|13774963|gb|AAK39109.1|AF356186_1/0/autoimmune infertility-related protein, partial [Mus musculus]" 226720 1789 0.01 0.03 1.584962501 Up 0.118385423 Becn2 beclin 2 K08334|1|1e-136|489|cge:100751252|beclin 1 - - - gi|595582285|ref|NP_001277621.1|/0/beclin-2 [Mus musculus] 66716 1868 0.033333333 0.01 -1.736965594 Down 0.118385423 Ccer1 coiled-coil glutamate-rich protein 1 - - - - - 50930 1869 0.033333333 0.01 -1.736965594 Down 0.118385423 Tnfsf14 "tumor necrosis factor (ligand) superfamily, member 14" K05477|1|6e-124|447|mmu:50930|tumor necrosis factor ligand superfamily member 14 - - - - 234988 2155 0.03 0.01 -1.584962501 Down 0.118385423 Mbd3l2 methyl-CpG binding domain protein 3-like 2 K11591|1|8e-09|65.1|lcm:102354135|methyl-CpG-binding domain protein 3 - - - gi|255522833|ref|NP_659183.3|/2.20803e-123/methyl-CpG binding domain protein 3-like 2 [Mus musculus] 14051 4099 0.01 0.03 1.584962501 Up 0.118385423 Eya4 EYA transcriptional coactivator and phosphatase 4 K17622|1|0.0|1100|mmu:14051|eyes absent homolog 4 [EC:3.1.3.48] - - - - 234329 3633 0.03 0.01 -1.584962501 Down 0.118385423 Trim60 tripartite motif-containing 60 K12029|1|0.0|951|mmu:234329|tripartite motif-containing protein 60/61 - GO:0046914//transition metal ion binding - gi|24233550|ref|NP_694737.1|/0/tripartite motif-containing protein 60 [Mus musculus] 100039753 1796 0.01 0.03 1.584962501 Up 0.118385423 Gm20815 "predicted gene, 20815" - - - - gi|295148165|ref|NP_001017394.2|/1.26051e-121/spermiogenesis specific transcript on the Y family member [Mus musculus] 100039045 3342 0.03 0.01 -1.584962501 Down 0.118385423 Gm10471 predicted gene 10471 - - - - "gi|148668757|gb|EDL01004.1|/3.61458e-110/mCG129471, partial [Mus musculus]" 11441 2091 0.03 0.01 -1.584962501 Down 0.118385423 Chrna7 "cholinergic receptor, nicotinic, alpha polypeptide 7" K04809|1|0.0|976|mmu:11441|nicotinic acetylcholine receptor alpha-7 - - - - 74556 1798 0.01 0.033333333 1.736965594 Up 0.118385423 Themis3 thymocyte selection associated family member 3 - - - - gi|268370023|ref|NP_083274.1|/0/protein THEMIS3 [Mus musculus] 666919 2081 0.03 0.01 -1.584962501 Down 0.118385423 Gm8363 "non-SMC condensin II complex, subunit H2 pseudogene" K11490|1|0.0|325|mmu:52683|condensin-2 complex subunit H2 - - GO:0030217//T cell differentiation gi|169646203|ref|NP_001108604.1|/0/condensin-2 complex subunit H2 isoform a [Mus musculus] 71979 1814 0.01 0.03 1.584962501 Up 0.118385423 Prr23a3 "proline rich 23A, member 3" - - - - gi|197927238|ref|NP_082309.1|/1.67988e-97/proline-rich protein 23A3 [Mus musculus] 332937 2117 0.01 0.03 1.584962501 Up 0.118385423 Tfap2e "transcription factor AP-2, epsilon" K09179|1|0.0|669|mmu:332937|transcription factor AP-2 epsilon GO:0043231//intracellular membrane-bounded organelle GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity GO:0006366//transcription from RNA polymerase II promoter gi|120444920|ref|NP_945198.2|/0/transcription factor AP-2-epsilon [Mus musculus] 625167 1694 0.01 0.03 1.584962501 Up 0.118385423 Gm6559 predicted gene 6559 - - - - - 619326 1898 0.01 0.03 1.584962501 Up 0.118385423 9130409I23Rik RIKEN cDNA 9130409I23 gene K04712|1|9e-174|612|mmu:619326|sphingolipid Delta-4 desaturase [EC:1.14.-.-] GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0031090//organelle membrane GO:0016491//oxidoreductase activity GO:0006633//fatty acid biosynthetic process;GO:0006665//sphingolipid metabolic process;GO:0006796//phosphate-containing compound metabolic process gi|74203569|dbj|BAE23057.1|/0/unnamed protein product [Mus musculus] 18703 3849 0.033333333 0.01 -1.736965594 Down 0.118385423 Pigr polymeric immunoglobulin receptor K13073|1|0.0|1456|mmu:18703|polymeric immunoglobulin receptor "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031224//intrinsic component of membrane;GO:0010008//endosome membrane" - - gi|31981570|ref|NP_035212.2|/0/polymeric immunoglobulin receptor precursor [Mus musculus] 70948 2228 0.01 0.033333333 1.736965594 Up 0.118385423 Wdr20rt "WD repeat domain 20, retrogene" K06100|1|1e-97|360|aam:106490508|symplekin;K12602|5|2e-11|73.9|api:100164117|WD repeat-containing protein 61 - - - gi|21735451|ref|NP_081890.1|/0/WD repeat-containing protein 20 [Mus musculus] 17172 2259 0.03 0.01 -1.584962501 Down 0.118385423 Ascl1 achaete-scute family bHLH transcription factor 1 K09067|1|3e-82|308|mmu:17172|achaete-scute complex protein - - - - 11448 1599 0.01 0.033333333 1.736965594 Up 0.118385423 Chrne "cholinergic receptor, nicotinic, epsilon polypeptide" K04817|1|0.0|919|mmu:11448|nicotinic acetylcholine receptor epsilon GO:0031224//intrinsic component of membrane;GO:0097060//synaptic membrane GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0044765//single-organism transport;GO:0006873//cellular ion homeostasis gi|6752950|ref|NP_033733.1|/0/acetylcholine receptor subunit epsilon precursor [Mus musculus] 245128 3466 0.01 0.033333333 1.736965594 Up 0.118385423 AU018091 expressed sequence AU018091 "K13865|1|0.0|1055|rno:292543|solute carrier family 7 (cationic amino acid transporter), member 3" GO:0031224//intrinsic component of membrane - - gi|261823948|ref|NP_001004153.2|/0/cationic amino acid transporter 5 [Mus musculus] 17339 2183 0.01 0.03 1.584962501 Up 0.118385423 Mip major intrinsic protein of lens fiber K09863|1|5e-133|477|mmu:17339|aquaporin-0 - - - - 18378 2168 0.01 0.03 1.584962501 Up 0.118385423 Omp olfactory marker protein K08574|1|9e-77|290|myb:102240924|calpain-5 [EC:3.4.22.-] GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0044297//cell body GO:0060089;GO:0033218//amide binding GO:0007606//sensory perception of chemical stimulus;GO:0007399//nervous system development;GO:0007154//cell communication gi|537195894|gb|ERE78208.1|/3.58309e-89/olfactory marker protein [Cricetulus griseus] 330450 3397 2.6 2.693333333 0.050881169 Up 0.118253789 Far2 fatty acyl CoA reductase 2 K13356|1|0.0|1014|mmu:330450|alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84] GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0044439 "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0036094//small molecule binding" GO:0006633//fatty acid biosynthetic process;GO:0035337 gi|30520289|ref|NP_848912.1|/0/fatty acyl-CoA reductase 2 [Mus musculus] 212398 2176 2.326666667 2.416666667 0.054753959 Up 0.118253789 Frat2 frequently rearranged in advanced T cell lymphomas 2 K03096|1|2e-67|259|mmu:212398|frequently rearranged in advanced T-cell lymphomas 2;K03069|3|2e-49|199|mmu:14296|frequently rearranged in advanced T-cell lymphomas 1 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0006886//intracellular protein transport gi|29243970|ref|NP_808271.1|/1.46999e-66/GSK-3-binding protein FRAT2 [Mus musculus] 77652 3755 2.35 2.44 0.054220391 Up 0.118253789 Zfp955a zinc finger protein 955A K09228|1|1e-172|610|ngi:103736473|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|40254149|ref|NP_084228.2|/0/zinc finger protein 883A [Mus musculus] 319638 2716 2.793333333 2.706666667 -0.045470517 Down 0.118253789 Nt5dc1 5'-nucleotidase domain containing 1 K01794|1|2e-130|469|pss:102445811|chondroitin-glucuronate 5-epimerase [EC:5.1.3.19];K13702|2|2e-55|220|xtr:100135182|abhydrolase domain-containing protein 10 [EC:3.1.1.93];K01081|3|1e-18|98.2|cbr:CBG02038|5'-nucleotidase [EC:3.1.3.5] - GO:0043169//cation binding;GO:0003824//catalytic activity - gi|110626010|ref|NP_795942.2|/0/5'-nucleotidase domain-containing protein 1 [Mus musculus] 78697 3907 2.71 2.803333333 0.048850448 Up 0.118253789 Pus7 pseudouridylate synthase 7 K06176|1|0.0|1265|mmu:78697|tRNA pseudouridine13 synthase [EC:5.4.99.27] - - - - 107197 847 33.54333333 34.00333333 0.019650118 Up 0.118159765 Uqcc3 ubiquinol-cytochrome c reductase complex assembly factor 3 - - "GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006796//phosphate-containing compound metabolic process gi|237858808|ref|NP_001153828.1|/8.13697e-30/ubiquinol-cytochrome-c reductase complex assembly factor 3 precursor [Mus musculus] 72749 4239 0.31 0.273333333 -0.181606806 Down 0.118103351 Tonsl "tonsoku-like, DNA repair protein" K09257|1|0.0|2326|mmu:72749|NF-kappa-B inhibitor-like protein 2 GO:0008023//transcription elongation factor complex;GO:0005657//replication fork GO:0005515//protein binding GO:0000725//recombinational repair gi|187608797|ref|NP_898914.3|/0/tonsoku-like protein [Mus musculus] 215243 2142 0.3 0.34 0.180572246 Up 0.118103351 Traf3ip3 TRAF3 interacting protein 3 K15680|1|1e-29|134|tgu:100222111|corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146] - - - - 791338 1686 0.363333333 0.32 -0.183221824 Down 0.118103351 Gm10190 predicted gene 10190 K10591|1|5e-06|55.5|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] - - - "gi|148706577|gb|EDL38524.1|/2.98463e-93/mCG17908, isoform CRA_c [Mus musculus]" 620016 1006 31.17333333 30.72666667 -0.020821162 Down 0.118009327 Gm12669 glutaredoxin 3 pseudogene K15216|1|3e-37|158|tsp:Tsp_09255|RNA polymerase I-specific transcription initiation factor RRN3;K07390|3|2e-22|108|loa:LOAG_09509|monothiol glutaredoxin GO:0031674//I band GO:0043169//cation binding;GO:0051540;GO:0019901//protein kinase binding;GO:0015036//disulfide oxidoreductase activity GO:0003300//cardiac muscle hypertrophy;GO:0008016//regulation of heart contraction;GO:0044710;GO:0019725//cellular homeostasis gi|31981269|ref|NP_075629.2|/1.92509e-174/glutaredoxin-3 [Mus musculus] 108037 2303.14 26.99333333 27.44666667 0.024027806 Up 0.118009327 Shmt2 serine hydroxymethyltransferase 2 (mitochondrial) K00600|1|0.0|977|rno:299857|glycine hydroxymethyltransferase [EC:2.1.2.1] GO:0005856//cytoskeleton;GO:0019866//organelle inner membrane;GO:0005759//mitochondrial matrix;GO:0005740//mitochondrial envelope;GO:0005856//cytoskeleton;GO:0019866//organelle inner membrane;GO:0005759//mitochondrial matrix;GO:0005740//mitochondrial envelope "GO:0016742//hydroxymethyl-, formyl- and related transferase activity;GO:0031406//carboxylic acid binding;GO:0005515//protein binding;GO:0004793//threonine aldolase activity;GO:0016742//hydroxymethyl-, formyl- and related transferase activity;GO:0031406//carboxylic acid binding;GO:0005515//protein binding;GO:0004793//threonine aldolase activity" GO:0051260//protein homooligomerization;GO:0006730//one-carbon metabolic process;GO:0006545//glycine biosynthetic process;GO:0006563//L-serine metabolic process;GO:0008283//cell proliferation;GO:0051260//protein homooligomerization;GO:0006730//one-carbon metabolic process;GO:0006545//glycine biosynthetic process;GO:0006563//L-serine metabolic process;GO:0008283//cell proliferation "gi|148692564|gb|EDL24511.1|/0/serine hydroxymethyl transferase 2 (mitochondrial), isoform CRA_b, partial [Mus musculus]" 69548 4861 4.386666667 4.496666667 0.035730859 Up 0.117952913 2310015A10Rik RIKEN cDNA 2310015A10 gene - - - - "gi|148670710|gb|EDL02657.1|/9.84027e-19/mCG63843, isoform CRA_b [Mus musculus]" 93730 3438 4.006666667 3.9 -0.038928366 Down 0.117952913 Lztfl1 leucine zipper transcription factor-like 1 K19400|1|3e-145|519|mmu:93730|leucine zipper transcription factor-like protein 1 GO:0044424 GO:0005515//protein binding GO:0033365//protein localization to organelle gi|15277319|ref|NP_201579.1|/2.29553e-144/leucine zipper transcription factor-like protein 1 [Mus musculus] 69181 2137 3.82 3.713333333 -0.040857811 Down 0.117952913 Dyrk2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 K18669|1|0.0|1186|mmu:69181|dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1] GO:0031981//nuclear lumen;GO:0043234//protein complex GO:0032182//ubiquitin-like protein binding;GO:0046914//transition metal ion binding;GO:0032550;GO:0004672//protein kinase activity GO:0007166//cell surface receptor signaling pathway;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006468//protein phosphorylation;GO:0005978//glycogen biosynthetic process gi|67846105|ref|NP_001014412.1|/0/dual specificity tyrosine-phosphorylation-regulated kinase 2 [Mus musculus] 79362 6015.53 3.826666667 3.72 -0.040785615 Down 0.117952913 Bhlhe41 "basic helix-loop-helix family, member e41" K03730|1|2e-166|590|mmu:79362|class B basic helix-loop-helix protein 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043234//protein complex "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0019899//enzyme binding;GO:0043425//bHLH transcription factor binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0019899//enzyme binding;GO:0043425//bHLH transcription factor binding" "GO:0009605//response to external stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0010830//regulation of myotube differentiation;GO:0007623//circadian rhythm;GO:0006366//transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0010830//regulation of myotube differentiation;GO:0007623//circadian rhythm" gi|13277378|ref|NP_077789.1|/3.63462e-159/class E basic helix-loop-helix protein 41 isoform 1 [Mus musculus] 12830 6503 4.296666667 4.19 -0.036267614 Down 0.117952913 Col4a5 "collagen, type IV, alpha 5" "K06237|1|3e-161|573|mmu:12830|collagen, type IV, alpha" GO:0005604//basement membrane;GO:0005604//basement membrane - - gi|74224660|dbj|BAE37876.1|/2.60929e-160/unnamed protein product [Mus musculus] 69179 3754 3.766666667 3.656666667 -0.042759247 Down 0.117952913 Tmem110 transmembrane protein 110 K20179|1|5e-52|209|tsp:Tsp_09249|vacuolar protein sorting-associated protein 11 - - - - 215335 5280 3.59 3.48 -0.044896538 Down 0.117952913 Slc36a1 "solute carrier family 36 (proton/amino acid symporter), member 1" K14209|1|0.0|739|mmu:215335|solute carrier family 36 (proton-coupled amino acid transporter) GO:0031224//intrinsic component of membrane;GO:0005764//lysosome GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0005416//cation:amino acid symporter activity GO:0006818//hydrogen transport;GO:0003333//amino acid transmembrane transport;GO:0006812//cation transport;GO:0015807//L-amino acid transport gi|145207965|ref|NP_694779.3|/0/proton-coupled amino acid transporter 1 [Mus musculus] 17257 10452 4.426666667 4.54 0.036471557 Up 0.117952913 Mecp2 methyl CpG binding protein 2 K11588|1|2e-163|580|mmu:17257|methyl CpG binding protein 2 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0044444//cytoplasmic part GO:0003690//double-stranded DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0043565//sequence-specific DNA binding;GO:0000217//DNA secondary structure binding;GO:0003690//double-stranded DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0003682//chromatin binding;GO:0003723//RNA binding;GO:0043565//sequence-specific DNA binding;GO:0000217//DNA secondary structure binding "GO:0008202//steroid metabolic process;GO:0016571//histone methylation;GO:0046471//phosphatidylglycerol metabolic process;GO:0044106;GO:0048167//regulation of synaptic plasticity;GO:0007416//synapse assembly;GO:0022037//metencephalon development;GO:0051899//membrane depolarization;GO:0002209//behavioral defense response;GO:0031175//neuron projection development;GO:0019751//polyol metabolic process;GO:0007613//memory;GO:0006351//transcription, DNA-templated;GO:0051705;GO:0007600//sensory perception;GO:0016458//gene silencing;GO:0009605//response to external stimulus;GO:0032940//secretion by cell;GO:0007626//locomotory behavior;GO:0003073//regulation of systemic arterial blood pressure;GO:0022904//respiratory electron transport chain;GO:0009064//glutamine family amino acid metabolic process;GO:0016573//histone acetylation;GO:0008283//cell proliferation;GO:0007632//visual behavior;GO:0043066//negative regulation of apoptotic process;GO:0050905//neuromuscular process;GO:0033036;GO:0048469//cell maturation;GO:0040029//regulation of gene expression, epigenetic;GO:0008202//steroid metabolic process;GO:0016571//histone methylation;GO:0046471//phosphatidylglycerol metabolic process;GO:0044106;GO:0048167//regulation of synaptic plasticity;GO:0007416//synapse assembly;GO:0022037//metencephalon development;GO:0051899//membrane depolarization;GO:0002209//behavioral defense response;GO:0031175//neuron projection development;GO:0019751//polyol metabolic process;GO:0007613//memory;GO:0006351//transcription, DNA-templated;GO:0051705;GO:0007600//sensory perception;GO:0016458//gene silencing;GO:0009605//response to external stimulus;GO:0032940//secretion by cell;GO:0007626//locomotory behavior;GO:0003073//regulation of systemic arterial blood pressure;GO:0022904//respiratory electron transport chain;GO:0009064//glutamine family amino acid metabolic process;GO:0016573//histone acetylation;GO:0008283//cell proliferation;GO:0007632//visual behavior;GO:0043066//negative regulation of apoptotic process;GO:0050905//neuromuscular process;GO:0033036;GO:0048469//cell maturation;GO:0040029//regulation of gene expression, epigenetic" gi|126517469|ref|NP_001075448.1|/3.36095e-160/methyl-CpG-binding protein 2 isoform 1 [Mus musculus] 328186 3772 26.32333333 26.76 0.023735926 Up 0.117830682 Gm10336 predicted gene 10336 - - - - gi|26338159|dbj|BAC32765.1|/2.62098e-56/unnamed protein product [Mus musculus] 13859 3082.45 29.90666667 29.48 -0.020730595 Down 0.117642634 Eps15l1 epidermal growth factor receptor pathway substrate 15-like 1 K12472|1|0.0|1447|mmu:13859|epidermal growth factor receptor substrate 15 GO:0012505//endomembrane system;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0043169//cation binding GO:0016192//vesicle-mediated transport;GO:0016192//vesicle-mediated transport gi|170784834|ref|NP_031970.2|/0/epidermal growth factor receptor substrate 15-like 1 isoform a [Mus musculus] 54401 2775 40 39.57333333 -0.015471409 Down 0.117642634 Ywhab "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide" K16197|1|2e-125|452|mmu:54401|14-3-3 protein beta/theta/zeta GO:0043234//protein complex;GO:0048770 GO:0003712//transcription cofactor activity;GO:0016491//oxidoreductase activity;GO:0019899//enzyme binding;GO:0016597//amino acid binding "GO:0044710;GO:0044093;GO:0006470//protein dephosphorylation;GO:0006351//transcription, DNA-templated;GO:0006935//chemotaxis;GO:0006886//intracellular protein transport;GO:0007264//small GTPase mediated signal transduction;GO:0051259//protein oligomerization;GO:0038127//ERBB signaling pathway;GO:0032507//maintenance of protein location in cell;GO:0012501//programmed cell death;GO:0006468//protein phosphorylation" gi|676275909|gb|KFO30241.1|/7.10387e-125/14-3-3 protein beta/alpha [Fukomys damarensis] 80880 2634 34.20666667 34.63333333 0.017883724 Up 0.117642634 Kank3 KN motif and ankyrin repeat domains 3 K15503|1|4e-18|96.3|aqu:100635111|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B GO:0044424 - GO:0032232//negative regulation of actin filament bundle assembly gi|13507632|ref|NP_109622.1|/0/KN motif and ankyrin repeat domain-containing protein 3 [Mus musculus] 231151 3791 7.126666667 7.28 0.030711003 Up 0.117623829 Tada2b transcriptional adaptor 2B K15127|1|0.0|705|rno:289717|transcriptional adapter 2-beta GO:0070461//SAGA-type complex GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|281427139|ref|NP_001163926.1|/0/transcriptional adapter 2-beta [Rattus norvegicus] 71617 2896 8.53 8.383333333 -0.025021747 Down 0.117623829 9130011E15Rik RIKEN cDNA 9130011E15 gene K17598|1|3e-15|87.0|smm:Smp_149780|synaptotagmin-like protein GO:0031224//intrinsic component of membrane - - gi|139947660|ref|NP_938038.2|/0/UPF0668 protein C10orf76 homolog [Mus musculus] 268859 4134.14 8.21 8.363333333 0.026695843 Up 0.117623829 Rbfox1 "RNA binding protein, fox-1 homolog (C. elegans) 1" K14946|1|0.0|654|mmu:268859|RNA binding protein fox-1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding GO:0050905//neuromuscular process;GO:0050657;GO:0008380//RNA splicing;GO:0008380//RNA splicing;GO:0050905//neuromuscular process gi|66792808|ref|NP_067452.2|/0/RNA binding protein fox-1 homolog 1 isoform gamma [Mus musculus] 76551 5511 7.903333333 7.756666667 -0.027024452 Down 0.117623829 Ccdc6 coiled-coil domain containing 6 K09288|1|1e-167|593|mmu:76551|coiled-coil domain-containing protein 6 GO:0043232 GO:0019904//protein domain specific binding - gi|589932624|ref|XP_006979106.1|/1.23211e-166/PREDICTED: coiled-coil domain-containing protein 6 [Peromyscus maniculatus bairdii] 209018 5027 6.756666667 6.61 -0.031661411 Down 0.117623829 Vps8 VPS8 CORVET complex subunit K20178|1|0.0|2716|mmu:209018|vacuolar protein sorting-associated protein 8 - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - "gi|148665188|gb|EDK97604.1|/0/mCG141781, isoform CRA_b, partial [Mus musculus]" 20912 2406 6.216666667 6.363333333 0.033641472 Up 0.117623829 Stxbp3 syntaxin binding protein 3 K15301|1|0.0|1193|mmu:20912|syntaxin-binding protein 3 - - - - 75416 2702 7.04 6.886666667 -0.03176958 Down 0.117623829 Nop14 NOP14 nucleolar protein K14766|1|0.0|1447|mmu:75416|nucleolar protein 14 GO:0031981//nuclear lumen;GO:0030686//90S preribosome GO:0003723//RNA binding "GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)" "gi|148705517|gb|EDL37464.1|/0/RIKEN cDNA 2610033H07, isoform CRA_b, partial [Mus musculus]" 13340 2490 6.58 6.733333333 0.033233303 Up 0.117623829 Slc29a2 "solute carrier family 29 (nucleoside transporters), member 2" "K15014|1|0.0|668|mmu:13340|solute carrier family 29 (equilibrative nucleoside transporter), member 1/2/3" GO:0016021//integral component of membrane;GO:0044459 GO:0015932//nucleobase-containing compound transmembrane transporter activity GO:0044763;GO:0015864//pyrimidine nucleoside transport;GO:0007589//body fluid secretion;GO:0015855//pyrimidine nucleobase transport;GO:0006863//purine nucleobase transport;GO:0032868//response to insulin gi|194248086|ref|NP_031880.2|/0/equilibrative nucleoside transporter 2 [Mus musculus] 215632 4700 0.32 0.36 0.169925001 Up 0.117482794 Psd4 pleckstrin and Sec7 domain containing 4 K12494|1|0.0|1812|mmu:215632|PH and SEC7 domain-containing protein GO:0016020//membrane GO:0008289//lipid binding GO:0032011//ARF protein signal transduction gi|29243984|ref|NP_808279.1|/0/PH and SEC7 domain-containing protein 4 [Mus musculus] 68355 826 0.39 0.346666667 -0.169925001 Down 0.117482794 2010204K13Rik RIKEN cDNA 2010204K13 gene - - - - - 319909 2965 0.33 0.37 0.165059246 Up 0.117482794 Ism1 "isthmin 1, angiogenesis inhibitor" K16857|1|5e-06|56.2|cfa:487486|thrombospondin 1 - - - - 72373 876 0.286666667 0.323333333 0.173648087 Up 0.117482794 Psca prostate stem cell antigen K06846|1|3e-11|71.2|mgp:104910461|lymphocyte antigen 6 complex locus protein D/E/G6/H - - - gi|21312316|ref|NP_082492.1|/3.85709e-54/prostate stem cell antigen precursor [Mus musculus] 235106 1808 0.383333333 0.34 -0.173064709 Down 0.117482794 Ntm neurotrimin K06774|1|0.0|671|mmu:235106|neurotrimin GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0008037//cell recognition gi|31982044|ref|NP_758494.2|/0/neurotrimin precursor [Mus musculus] 15183 2005 32.78333333 32.36666667 -0.018453757 Down 0.117435782 Hdac3 histone deacetylase 3 K11404|1|0.0|904|ngi:103736071|histone deacetylase 3 [EC:3.5.1.98] GO:0031981//nuclear lumen;GO:0044427;GO:0005819//spindle GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0003682//chromatin binding;GO:0019899//enzyme binding GO:0000278//mitotic cell cycle;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0006461//protein complex assembly;GO:0016575//histone deacetylation;GO:0006915//apoptotic process;GO:0010830//regulation of myotube differentiation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007254//JNK cascade;GO:0051726//regulation of cell cycle;GO:0006629//lipid metabolic process;GO:0035264//multicellular organism growth;GO:0007623//circadian rhythm "gi|440892173|gb|ELR45488.1|/0/histone deacetylase 3, partial [Bos mutus]" 384309 3637 1.15 1.086666667 -0.081724397 Down 0.117266539 Trim56 tripartite motif-containing 56 K12026|1|0.0|1310|mmu:384309|tripartite motif-containing protein 56 [EC:2.3.2.27] GO:0044424 GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0032606//type I interferon production;GO:0006952//defense response;GO:0002252;GO:0000209//protein polyubiquitination;GO:0034097//response to cytokine gi|41235779|ref|NP_958761.1|/0/E3 ubiquitin-protein ligase TRIM56 [Mus musculus] 16498 3575.61 1.183333333 1.12 -0.079357792 Down 0.117266539 Kcnab2 "potassium voltage-gated channel, shaker-related subfamily, beta member 2" "K04883|1|0.0|739|rno:29738|potassium voltage-gated channel Shaker-related subfamily A, beta member 2" GO:0031224//intrinsic component of membrane;GO:0033267;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0033267;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0033267;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0033267;GO:0044424 GO:0005488//binding;GO:0016247//channel regulator activity;GO:0005267//potassium channel activity;GO:0016247//channel regulator activity;GO:0005267//potassium channel activity;GO:0016247//channel regulator activity;GO:0005267//potassium channel activity;GO:0005488//binding;GO:0016247//channel regulator activity;GO:0005267//potassium channel activity GO:0007267//cell-cell signaling;GO:0051259//protein oligomerization;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0007267//cell-cell signaling;GO:0051259//protein oligomerization;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0007267//cell-cell signaling;GO:0051259//protein oligomerization;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0007267//cell-cell signaling;GO:0051259//protein oligomerization;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|358030291|ref|NP_001239583.1|/0/voltage-gated potassium channel subunit beta-2 isoform 2 [Mus musculus] 240041 6549.82 0.953333333 1.01 0.083302647 Up 0.117266539 Zfp945 zinc finger protein 945 K09228|1|0.0|941|cge:100763047|KRAB domain-containing zinc finger protein - GO:0043169//cation binding;GO:0043169//cation binding - gi|159110675|ref|NP_001103724.1|/0/uncharacterized protein LOC240041 isoform a [Mus musculus] 269473 7175 1.04 1.1 0.080919995 Up 0.117266539 Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 K19511|1|1e-53|215|clv:102088601|peroxidase [EC:1.11.1.7] GO:0044424;GO:0031224//intrinsic component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane - - "gi|148675623|gb|EDL07570.1|/0/leucine-rich repeats and immunoglobulin-like domains 2, isoform CRA_b, partial [Mus musculus]" 382793 6275 1.1 1.043333333 -0.076303367 Down 0.117266539 Mtx3 metaxin 3 K17776|1|4e-165|585|mmu:382793|metaxin - - - gi|242397501|ref|NP_001156417.1|/3.85217e-164/metaxin-3 [Mus musculus] 66897 3911 1.183333333 1.123333333 -0.075070433 Down 0.117266539 Naa16 "N(alpha)-acetyltransferase 16, NatA auxiliary subunit" K00670|1|0.0|1665|mmu:66897|peptide alpha-N-acetyltransferase [EC:2.3.1.88] - GO:0003824//catalytic activity - "gi|21313242|ref|NP_080108.1|/0/N-alpha-acetyltransferase 16, NatA auxiliary subunit [Mus musculus]" 93699 4498 0.616666667 0.57 -0.113528946 Down 0.117200722 Pcdhgb1 "protocadherin gamma subfamily B, 1" K16496|1|0.0|1711|mmu:93699|protocadherin gamma subfamily B GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|148747543|ref|NP_291052.3|/0/protocadherin gamma-B1 precursor [Mus musculus] 75079 2985 0.693333333 0.643333333 -0.107982681 Down 0.117200722 Zbtb49 zinc finger and BTB domain containing 49 K10500|1|6e-80|301|gja:107111606|zinc finger and BTB domain-containing protein 17 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|58037397|ref|NP_083438.1|/0/zinc finger and BTB domain-containing protein 49 [Mus musculus] 433586 6514 0.653333333 0.706666667 0.11321061 Up 0.117200722 Maml3 mastermind like 3 (Drosophila) K06061|1|0.0|1785|mmu:433586|mastermind GO:0005654//nucleoplasm GO:0003712//transcription cofactor activity GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter gi|205277330|ref|NP_001004176.2|/0/mastermind-like protein 3 [Mus musculus] 57810 7236 0.573333333 0.62 0.112894056 Up 0.117200722 Cdon cell adhesion molecule-related/down-regulated by oncogenes K20033|1|0.0|2511|mmu:57810|cell adhesion molecule-related/down-regulated by oncogenes - - - - 73569 3331 0.723333333 0.67 -0.110499541 Down 0.117200722 Vgll3 vestigial like family member 3 - GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated" gi|254750654|ref|NP_082848.1|/3.77416e-160/transcription cofactor vestigial-like protein 3 [Mus musculus] 226654 551 0.65 0.603333333 -0.107484427 Down 0.117200722 Tstd1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 K06089|1|1e-26|120|asn:102383480|junctional adhesion molecule 1;K01011|2|8e-14|78.6|dme:Dmel_CG12279|thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] - GO:0003824//catalytic activity - "gi|148707134|gb|EDL39081.1|/4.15622e-77/mCG8648, isoform CRA_b, partial [Mus musculus]" 22427 6273 0.66 0.613333333 -0.105794664 Down 0.117200722 Wrn Werner syndrome homolog (human) K10900|1|0.0|2701|mmu:22427|werner syndrome ATP-dependent helicase [EC:3.6.4.12] GO:0031981//nuclear lumen;GO:0005815//microtubule organizing center;GO:0031981//nuclear lumen;GO:0005815//microtubule organizing center GO:0046914//transition metal ion binding;GO:0032550;GO:0004527//exonuclease activity;GO:0042802//identical protein binding;GO:0000217//DNA secondary structure binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0046914//transition metal ion binding;GO:0032550;GO:0004527//exonuclease activity;GO:0042802//identical protein binding;GO:0000217//DNA secondary structure binding;GO:0004003//ATP-dependent DNA helicase activity GO:0010332//response to gamma radiation;GO:0043085//positive regulation of catalytic activity;GO:0007275//multicellular organism development;GO:0007569//cell aging;GO:0006915//apoptotic process;GO:0009411//response to UV;GO:0040008//regulation of growth;GO:0044765//single-organism transport;GO:0009154//purine ribonucleotide catabolic process;GO:0032392//DNA geometric change;GO:0006281//DNA repair;GO:0010332//response to gamma radiation;GO:0043085//positive regulation of catalytic activity;GO:0007275//multicellular organism development;GO:0007569//cell aging;GO:0006915//apoptotic process;GO:0009411//response to UV;GO:0040008//regulation of growth;GO:0044765//single-organism transport;GO:0009154//purine ribonucleotide catabolic process;GO:0032392//DNA geometric change;GO:0006281//DNA repair gi|170763502|ref|NP_035851.3|/0/Werner syndrome ATP-dependent helicase homolog [Mus musculus] 331474 4330 0.676666667 0.73 0.109451142 Up 0.117200722 Rgag4 retrotransposon gag domain containing 4 - - - - gi|60360096|dbj|BAD90267.1|/0/mKIAA2001 protein [Mus musculus] 74763 2422.18 29.76 29.35666667 -0.019686361 Down 0.117097296 Naa60 "N(alpha)-acetyltransferase 60, NatF catalytic subunit" K17807|1|3e-38|163|tsp:Tsp_10027|mitochondrial translocator assembly and maintenance protein 41;K11067|2|8e-16|88.6|ngi:103738424|N-acetylglutamate synthase [EC:2.3.1.1];K14021|3|3e-06|57.0|smm:Smp_131280|Bcl-2 homologous antagonist/killer GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system GO:0034212//peptide N-acetyltransferase activity;GO:0004402//histone acetyltransferase activity;GO:0034212//peptide N-acetyltransferase activity;GO:0004402//histone acetyltransferase activity GO:0034728//nucleosome organization;GO:0016573//histone acetylation;GO:0006474//N-terminal protein amino acid acetylation;GO:0034728//nucleosome organization;GO:0016573//histone acetylation;GO:0006474//N-terminal protein amino acid acetylation gi|21312874|ref|NP_083366.1|/3.75104e-116/N-alpha-acetyltransferase 60 isoform 1 [Mus musculus] 26413 3795.7 35.85333333 36.25333333 0.016006396 Up 0.117097296 Mapk1 mitogen-activated protein kinase 1 K04371|1|0.0|687|rno:116590|mitogen-activated protein kinase 1/3 [EC:2.7.11.24] - - - "gi|148665020|gb|EDK97436.1|/0/mitogen activated protein kinase 1, isoform CRA_b, partial [Mus musculus]" 21927 3698.97 29.65 30.05 0.019332886 Up 0.117097296 Tnfaip1 "tumor necrosis factor, alpha-induced protein 1 (endothelial)" K15074|1|0.0|641|mmu:21927|BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein GO:0031981//nuclear lumen;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031981//nuclear lumen;GO:0031461//cullin-RING ubiquitin ligase complex GO:0017048//Rho GTPase binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0017048//Rho GTPase binding;GO:0019787//ubiquitin-like protein transferase activity "GO:0006351//transcription, DNA-templated;GO:0007266//Rho protein signal transduction;GO:0007275//multicellular organism development;GO:0012501//programmed cell death;GO:0051017//actin filament bundle assembly;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0048870//cell motility;GO:0051259//protein oligomerization;GO:0002376//immune system process;GO:0032446//protein modification by small protein conjugation;GO:0006260//DNA replication;GO:0006351//transcription, DNA-templated;GO:0007266//Rho protein signal transduction;GO:0007275//multicellular organism development;GO:0012501//programmed cell death;GO:0051017//actin filament bundle assembly;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0048870//cell motility;GO:0051259//protein oligomerization;GO:0002376//immune system process;GO:0032446//protein modification by small protein conjugation;GO:0006260//DNA replication" "gi|148683641|gb|EDL15588.1|/0/tumor necrosis factor, alpha-induced protein 1 (endothelial), isoform CRA_a, partial [Mus musculus]" 18767 3683 33.96 33.55666667 -0.017237045 Down 0.117097296 Pkia "protein kinase inhibitor, alpha" K15985|1|3e-39|167|rro:104665838|cAMP-dependent protein kinase inhibitor alpha GO:0043231//intracellular membrane-bounded organelle "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0030291//protein serine/threonine kinase inhibitor activity" GO:0006366//transcription from RNA polymerase II promoter;GO:0006469//negative regulation of protein kinase activity;GO:0006606//protein import into nucleus;GO:0000086//G2/M transition of mitotic cell cycle gi|568920571|ref|XP_006530119.1|/1.83573e-38/PREDICTED: cAMP-dependent protein kinase inhibitor alpha isoform X1 [Mus musculus] 108121 907 28.35666667 28.76 0.020375722 Up 0.117097296 U2af1 U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1 K12836|1|5e-90|333|pbi:103055544|splicing factor U2AF 35 kDa subunit GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0005681//spliceosomal complex;GO:0016604//nuclear body GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding GO:0000377;GO:0006405//RNA export from nucleus;GO:0006397//mRNA processing;GO:0006366//transcription from RNA polymerase II promoter;GO:0000377;GO:0006405//RNA export from nucleus;GO:0006397//mRNA processing;GO:0006366//transcription from RNA polymerase II promoter gi|829810149|ref|XP_012629014.1|/3.00671e-89/PREDICTED: splicing factor U2AF 35 kDa subunit [Microcebus murinus] 72575 2707 0.18 0.146666667 -0.295455884 Down 0.117087893 C430049B03Rik RIKEN cDNA C430049B03 gene - - - - - 76798 3358 0.116666667 0.143333333 0.296981738 Up 0.117087893 Srrm4os "serine/arginine repetitive matrix 4, opposite strand" - - - - "gi|148687879|gb|EDL19826.1|/6.89844e-69/mCG145325, isoform CRA_a, partial [Mus musculus]" 320664 3665.38 0.11 0.136666667 0.313157885 Up 0.117087893 Cass4 Cas scaffolding protein family member 4 K16832|1|3e-51|206|cmk:103187050|enhancer of filamentation 1 GO:0043232;GO:0043232;GO:0043232 - GO:0022610;GO:0022610;GO:0022610 gi|449310776|ref|NP_001263352.1|/0/cas scaffolding protein family member 4 isoform 4 [Mus musculus] 21983 3509 0.176666667 0.143333333 -0.3016557 Down 0.117087893 Tpbg trophoblast glycoprotein K01315|1|3e-19|100|bfo:BRAFLDRAFT_71581|plasminogen [EC:3.4.21.7];K16661|2|6e-18|96.3|aml:100472519|reticulon-4 receptor-like 2;K16351|3|5e-17|93.2|bfo:BRAFLDRAFT_88426|netrin-G2 ligand;K06260|4|2e-16|90.9|oaa:100080952|platelet glycoprotein V GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - - gi|913491397|ref|XP_013201801.1|/0/PREDICTED: trophoblast glycoprotein isoform X1 [Microtus ochrogaster] 68764 2953 0.113333333 0.14 0.304854582 Up 0.117087893 Cdhr3 cadherin-related family member 3 K16503|1|0.0|1528|mmu:68764|cadherin-related family member 3 GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|67846107|ref|NP_001019649.1|/0/cadherin-related family member 3 precursor [Mus musculus] 77022 1275 0.153333333 0.123333333 -0.31410859 Down 0.117087893 2700099C18Rik "NDC80 homolog, kinetochore complex component pseudogene" K11547|1|2e-60|235|ocu:100349582|kinetochore protein NDC80 - - - - 112415 4628 0.16 0.13 -0.299560282 Down 0.117087893 C030039L03Rik zinc finger protein 607B K09228|1|0.0|1375|mmu:112415|KRAB domain-containing zinc finger protein - - - - 18802 2981 0.136666667 0.17 0.314873337 Up 0.117087893 Plcd4 "phospholipase C, delta 4" "K05857|1|0.0|1560|mmu:18802|phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]" GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0004629//phospholipase C activity;GO:0046872//metal ion binding;GO:0060089;GO:0008289//lipid binding;GO:0004629//phospholipase C activity;GO:0046872//metal ion binding;GO:0060089;GO:0008289//lipid binding GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0007338//single fertilization;GO:0006629//lipid metabolic process;GO:0007165//signal transduction;GO:0007338//single fertilization "gi|125347171|ref|NP_683739.2|/0/1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform 2 [Mus musculus]" 20343 2213 0.176666667 0.143333333 -0.3016557 Down 0.117087893 Sell "selectin, lymphocyte" "K06495|1|0.0|820|mmu:20343|selectin, lymphocyte" GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0009986//cell surface GO:0008289//lipid binding;GO:0019899//enzyme binding;GO:0019899//enzyme binding;GO:0046625//sphingolipid binding;GO:0005539//glycosaminoglycan binding GO:0022610;GO:0046683//response to organophosphorus;GO:0006915//apoptotic process;GO:0070542//response to fatty acid;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0006950//response to stress;GO:0022610;GO:0046683//response to organophosphorus;GO:0006915//apoptotic process;GO:0070542//response to fatty acid;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0007599//hemostasis;GO:0006950//response to stress gi|6755454|ref|NP_035476.1|/0/L-selectin isoform 1 precursor [Mus musculus] 407810 4155 0.11 0.136666667 0.313157885 Up 0.117087893 BC046251 cDNA sequence BC046251 - - - - - 13371 6432 0.143333333 0.116666667 -0.296981738 Down 0.117087893 Dio2 "deiodinase, iodothyronine, type II" K17904|1|9e-148|528|mmu:13371|type II thyroxine 5'-deiodinase [EC:1.21.99.4] - - - - 626275 2364 0.146666667 0.12 -0.289506617 Down 0.116928053 A930012L18Rik RIKEN cDNA A930012L18 gene - - - - - 28240 7292 0.166666667 0.136666667 -0.286304185 Down 0.116928053 Trpm2 "transient receptor potential cation channel, subfamily M, member 2" K04977|1|0.0|2801|mmu:28240|transient receptor potential cation channel subfamily M member 2 [EC:3.6.1.13] GO:0031224//intrinsic component of membrane GO:0022890//inorganic cation transmembrane transporter activity;GO:0016462//pyrophosphatase activity;GO:0005261//cation channel activity GO:0044763;GO:0006979//response to oxidative stress;GO:0006816//calcium ion transport;GO:0006828//manganese ion transport;GO:0006814//sodium ion transport gi|261878536|ref|NP_612174.2|/0/transient receptor potential cation channel subfamily M member 2 [Mus musculus] 18483 2584.04 33.37333333 32.98666667 -0.016812791 Down 0.116852834 Palm paralemmin K16519|1|1e-164|582|mmu:18483|A-kinase anchor protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0030175//filopodium;GO:0016021//integral component of membrane;GO:0032589//neuron projection membrane;GO:0030175//filopodium;GO:0044424;GO:0032589//neuron projection membrane GO:0050780//dopamine receptor binding;GO:0050780//dopamine receptor binding GO:0051094//positive regulation of developmental process;GO:0022604//regulation of cell morphogenesis;GO:0051602//response to electrical stimulus;GO:0031346//positive regulation of cell projection organization;GO:0006612//protein targeting to membrane;GO:0007212//dopamine receptor signaling pathway;GO:0006996//organelle organization;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0007399//nervous system development;GO:0051094//positive regulation of developmental process;GO:0022604//regulation of cell morphogenesis;GO:0051602//response to electrical stimulus;GO:0031346//positive regulation of cell projection organization;GO:0006612//protein targeting to membrane;GO:0007212//dopamine receptor signaling pathway;GO:0006996//organelle organization;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0007399//nervous system development gi|239985639|ref|NP_075617.3|/0/paralemmin-1 isoform 1 [Mus musculus] 70661 6296 36.33 35.94 -0.015570957 Down 0.116852834 Sik3 SIK family kinase 3 K19009|1|0.0|2436|mmu:70661|serine/threonine-protein kinase SIK3 [EC:2.7.11.1] - - - - 24017 2612.64 31.64666667 31.25333333 -0.01804348 Down 0.116852834 Rnf13 ring finger protein 13 K15692|1|4e-124|446|mmu:24017|E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27] GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0019866//organelle inner membrane;GO:0005770//late endosome;GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0005770//late endosome;GO:0044446;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0019866//organelle inner membrane;GO:0005770//late endosome;GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0019866//organelle inner membrane;GO:0005770//late endosome;GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0019866//organelle inner membrane;GO:0005770//late endosome GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0016567//protein ubiquitination;GO:0016567//protein ubiquitination;GO:0016567//protein ubiquitination;GO:0016567//protein ubiquitination;GO:0016567//protein ubiquitination gi|6755338|ref|NP_036013.1|/6.0981e-128/E3 ubiquitin-protein ligase RNF13 isoform b precursor [Mus musculus] 232227 6427.03 28.19333333 28.58666667 0.019988345 Up 0.116852834 Iqsec1 IQ motif and Sec7 domain 1 K12495|1|0.0|1525|ngi:103730369|IQ motif and SEC7 domain-containing protein - - - gi|197304784|ref|NP_001127856.1|/0/IQ motif and SEC7 domain-containing protein 1 isoform b [Mus musculus] 27967 3820 23.79666667 24.18333333 0.023253612 Up 0.116852834 Cherp calcium homeostasis endoplasmic reticulum protein K12841|1|0.0|1009|mmu:27967|calcium homeostasis endoplasmic reticulum protein GO:0005789//endoplasmic reticulum membrane GO:0005515//protein binding GO:0051283//negative regulation of sequestering of calcium ion;GO:0008283//cell proliferation;GO:0042993//positive regulation of transcription factor import into nucleus "gi|148678853|gb|EDL10800.1|/0/calcium homeostasis endoplasmic reticulum protein, isoform CRA_a, partial [Mus musculus]" 72061 2247.31 27.64 27.26333333 -0.019795653 Down 0.116692993 2010111I01Rik RIKEN cDNA 2010111I01 gene K09606|1|1e-70|270|mmu:72061|aminopeptidase O [EC:3.4.11.-] - - - - 22319 2115 31.98666667 31.60333333 -0.017393924 Down 0.116692993 Vamp3 vesicle-associated membrane protein 3 K13505|1|4e-42|175|rno:29528|vesicle-associated membrane protein 3 GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0044459;GO:0030136//clathrin-coated vesicle;GO:0005768//endosome;GO:0042995//cell projection GO:0019905//syntaxin binding GO:0006887//exocytosis;GO:0001881//receptor recycling;GO:0006886//intracellular protein transport;GO:0065003;GO:0000904//cell morphogenesis involved in differentiation gi|6678553|ref|NP_033524.1|/3.52531e-41/vesicle-associated membrane protein 3 [Mus musculus] 22350 3070 26.15 25.76666667 -0.021305033 Down 0.116692993 Ezr ezrin K08007|1|0.0|1039|mmu:22350|villin 2 (ezrin) GO:0031981//nuclear lumen;GO:0005815//microtubule organizing center;GO:0015629//actin cytoskeleton;GO:0005902//microvillus;GO:0001726//ruffle;GO:0005924//cell-substrate adherens junction;GO:0042383//sarcolemma;GO:0031254//cell trailing edge;GO:0097386//glial cell projection;GO:0060187//cell pole;GO:0044459;GO:0044444//cytoplasmic part GO:0003779//actin binding GO:0022604//regulation of cell morphogenesis;GO:0016337//single organismal cell-cell adhesion;GO:0022406//membrane docking;GO:0007015//actin filament organization;GO:0061245//establishment or maintenance of bipolar cell polarity;GO:0030031//cell projection assembly;GO:0006935//chemotaxis;GO:0030154//cell differentiation gi|83921618|ref|NP_033536.2|/0/ezrin [Mus musculus] 70489 887 0.126666667 0.153333333 0.275634443 Up 0.116645981 5730405O15Rik RIKEN cDNA 5730405O15 gene - - - - "gi|148703753|gb|EDL35700.1|/5.69147e-37/mCG145547, partial [Mus musculus]" 234695 2504 0.156666667 0.19 0.278301162 Up 0.116645981 Rltpr "RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing" K20493|1|0.0|1074|mmu:234695|leucine-rich repeat-containing protein 16 - - - gi|755526655|ref|XP_011246660.1|/0/PREDICTED: leucine-rich repeat-containing protein 16C isoform X1 [Mus musculus] 15220 2821 0.126666667 0.153333333 0.275634443 Up 0.116645981 Foxq1 forkhead box Q1 K09410|1|1e-125|453|mmu:15220|forkhead box protein Q - - - gi|6716870|gb|AAC12973.2|/9.47023e-125/fork head transcription factor [Mus musculus] 209586 3977 25.82 26.18666667 0.020343428 Up 0.116476739 Nudcd3 NudC domain containing 3 K04515|1|2e-40|171|ccw:104683185|calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] - - - gi|30424587|ref|NP_776109.1|/0/nudC domain-containing protein 3 [Mus musculus] 72055 4587.42 31.06333333 31.43333333 0.01708262 Up 0.116476739 Slc38a10 "solute carrier family 38, member 10" "K14996|1|0.0|1946|mmu:72055|solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 10" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0030001//metal ion transport;GO:0046942//carboxylic acid transport;GO:0001501//skeletal system development;GO:0030001//metal ion transport;GO:0046942//carboxylic acid transport;GO:0001501//skeletal system development "gi|148702782|gb|EDL34729.1|/0/RIKEN cDNA 1810073N04, isoform CRA_a [Mus musculus]" 68112 2029.77 24 24.37333333 0.022269164 Up 0.116476739 Sdccag3 serologically defined colon cancer antigen 3 - GO:0044424;GO:0044424;GO:0044424 - - "gi|148676361|gb|EDL08308.1|/0/mCG18732, isoform CRA_b, partial [Mus musculus]" 70223 2661.75 33.01 33.37666667 0.015936741 Up 0.116476739 Nars asparaginyl-tRNA synthetase K01893|1|0.0|1114|mmu:70223|asparaginyl-tRNA synthetase [EC:6.1.1.22] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation "gi|219276601|ref|NP_001136422.1|/0/asparagine--tRNA ligase, cytoplasmic isoform 1 [Mus musculus]" 66094 487 31.76666667 32.13666667 0.016706582 Up 0.116476739 Lsm7 "LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated" K12626|1|5e-44|178|mmu:66094|U6 snRNA-associated Sm-like protein LSm7 - - - - 225849 2708 21.88666667 21.51666667 -0.024597654 Down 0.116476739 Ppp2r5b "protein phosphatase 2, regulatory subunit B', beta" K11584|1|0.0|787|mmu:225849|serine/threonine-protein phosphatase 2A regulatory subunit B' GO:0008287//protein serine/threonine phosphatase complex;GO:0044444//cytoplasmic part GO:0019888//protein phosphatase regulator activity;GO:0005488//binding GO:0070848//response to growth factor;GO:0006366//transcription from RNA polymerase II promoter;GO:0006461//protein complex assembly;GO:0010975//regulation of neuron projection development;GO:0007050//cell cycle arrest;GO:0001932//regulation of protein phosphorylation;GO:0009967//positive regulation of signal transduction;GO:0044093;GO:0010948//negative regulation of cell cycle process;GO:0030968//endoplasmic reticulum unfolded protein response gi|74186833|dbj|BAE20490.1|/0/unnamed protein product [Mus musculus] 17427 1837 0.16 0.133333333 -0.263034406 Down 0.116457934 Mns1 meiosis-specific nuclear structural protein 1 K12875|1|1e-19|100|dre:368893|apoptotic chromatin condensation inducer in the nucleus GO:0012505//endomembrane system;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0022403 "gi|148694304|gb|EDL26251.1|/0/meiosis-specific nuclear structural protein 1, isoform CRA_b, partial [Mus musculus]" 20497 3297.08 0.163333333 0.196666667 0.267933205 Up 0.116457934 Slc12a3 "solute carrier family 12, member 3" "K14426|1|0.0|1967|mmu:20497|solute carrier family 12 (sodium/chloride transporter), member 3" GO:0043226//organelle;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0043226//organelle;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0046873//metal ion transmembrane transporter activity;GO:0015377//cation:chloride symporter activity;GO:0046873//metal ion transmembrane transporter activity;GO:0015377//cation:chloride symporter activity GO:0015698//inorganic anion transport;GO:0044763;GO:0003096//renal sodium ion transport;GO:0015698//inorganic anion transport;GO:0044763;GO:0003096//renal sodium ion transport "gi|148679176|gb|EDL11123.1|/0/solute carrier family 12, member 3, isoform CRA_a, partial [Mus musculus]" 386463 2678 0.163333333 0.136666667 -0.257157839 Down 0.116457934 Cdsn corneodesmosin - - - - gi|569000843|ref|XP_006524606.1|/1.46251e-135/PREDICTED: corneodesmosin isoform X1 [Mus musculus] 408065 4079 0.193333333 0.16 -0.273018494 Down 0.116457934 Zfp456 zinc finger protein 456 K09228|1|0.0|997|mmu:408065|KRAB domain-containing zinc finger protein - GO:0046872//metal ion binding "GO:0006351//transcription, DNA-templated;GO:0003006//developmental process involved in reproduction" gi|123702020|ref|NP_001001186.3|/0/zinc finger protein 456 [Mus musculus] 237353 5796 0.196666667 0.163333333 -0.267933205 Down 0.116457934 Sh3rf3 SH3 domain containing ring finger 3 K12171|1|0.0|1489|mmu:237353|E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27] - - - "gi|148700264|gb|EDL32211.1|/0/RIKEN cDNA 4831416G18, isoform CRA_b, partial [Mus musculus]" 242705 4566.08 0.15 0.18 0.263034406 Up 0.116457934 E2f2 E2F transcription factor 2 K09389|1|0.0|790|mmu:242705|transcription factor E2F2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding "GO:0012501//programmed cell death;GO:0007049//cell cycle;GO:0006351//transcription, DNA-templated;GO:0012501//programmed cell death;GO:0007049//cell cycle;GO:0006351//transcription, DNA-templated" "gi|148697999|gb|EDL29946.1|/1.24366e-117/E2F transcription factor 2, isoform CRA_a, partial [Mus musculus]" 654824 921 6.583333333 6.44 -0.031757559 Down 0.116382715 Ankrd37 ankyrin repeat domain 37 K08803|1|3e-06|54.7|aqu:100633578|death-associated protein kinase [EC:2.7.11.1] - - - - 71523 1079.16 8.113333333 7.97 -0.025715038 Down 0.116382715 8430429K09Rik RIKEN cDNA 8430429K09 gene "K03847|1|1e-06|57.4|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - "gi|148708474|gb|EDL40421.1|/2.56128e-71/RIKEN cDNA 8430429K09, partial [Mus musculus]" 11991 6750.31 7.576666667 7.716666667 0.026414509 Up 0.116382715 Hnrnpd heterogeneous nuclear ribonucleoprotein D K13044|1|2e-117|427|bta:527471|heterogeneous nuclear ribonucleoprotein A/B/D GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0043565//sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003723//RNA binding;GO:0043565//sequence-specific DNA binding;GO:0036094//small molecule binding "GO:0043488//regulation of mRNA stability;GO:0006351//transcription, DNA-templated;GO:0000377;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-templated;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0043488//regulation of mRNA stability;GO:0051169//nuclear transport;GO:0006351//transcription, DNA-templated" gi|3747052|gb|AAC77437.1|/9.18088e-131/estrogen response element binding protein [Saguinus oedipus] 20466 5088.74 7.51 7.37 -0.027148288 Down 0.116382715 Sin3a "transcriptional regulator, SIN3A (yeast)" K11644|1|0.0|2273|mmu:20466|paired amphipathic helix protein Sin3a "GO:0070822//Sin3-type complex;GO:0000775//chromosome, centromeric region;GO:0070822//Sin3-type complex;GO:0000775//chromosome, centromeric region;GO:0070822//Sin3-type complex;GO:0000775//chromosome, centromeric region" GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0019213//deacetylase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0019213//deacetylase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0019213//deacetylase activity GO:0050691//regulation of defense response to virus by host;GO:0009636//response to toxic substance;GO:0006915//apoptotic process;GO:0035601//protein deacylation;GO:0002253//activation of immune response;GO:0043009//chordate embryonic development;GO:0043392//negative regulation of DNA binding;GO:0008104//protein localization;GO:0001678//cellular glucose homeostasis;GO:0006259//DNA metabolic process;GO:0006342//chromatin silencing;GO:0006366//transcription from RNA polymerase II promoter;GO:0000086//G2/M transition of mitotic cell cycle;GO:0035067//negative regulation of histone acetylation;GO:0034599//cellular response to oxidative stress;GO:0009719;GO:0050691//regulation of defense response to virus by host;GO:0009636//response to toxic substance;GO:0006915//apoptotic process;GO:0035601//protein deacylation;GO:0002253//activation of immune response;GO:0043009//chordate embryonic development;GO:0043392//negative regulation of DNA binding;GO:0008104//protein localization;GO:0001678//cellular glucose homeostasis;GO:0006259//DNA metabolic process;GO:0006342//chromatin silencing;GO:0006366//transcription from RNA polymerase II promoter;GO:0000086//G2/M transition of mitotic cell cycle;GO:0035067//negative regulation of histone acetylation;GO:0034599//cellular response to oxidative stress;GO:0009719;GO:0050691//regulation of defense response to virus by host;GO:0009636//response to toxic substance;GO:0006915//apoptotic process;GO:0035601//protein deacylation;GO:0002253//activation of immune response;GO:0043009//chordate embryonic development;GO:0043392//negative regulation of DNA binding;GO:0008104//protein localization;GO:0001678//cellular glucose homeostasis;GO:0006259//DNA metabolic process;GO:0006342//chromatin silencing;GO:0006366//transcription from RNA polymerase II promoter;GO:0000086//G2/M transition of mitotic cell cycle;GO:0035067//negative regulation of histone acetylation;GO:0034599//cellular response to oxidative stress;GO:0009719 gi|60359996|dbj|BAD90217.1|/0/mKIAA4126 protein [Mus musculus] 12802 3906 0.353333333 0.316666667 -0.158064846 Down 0.116345105 Cnr2 cannabinoid receptor 2 (macrophage) K04278|1|0.0|675|mmu:12802|cannabinoid receptor 2 (macrophage) GO:0031224//intrinsic component of membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body GO:0004930//G-protein coupled receptor activity "GO:0001508//action potential;GO:0007600//sensory perception;GO:0006954//inflammatory response;GO:0002695//negative regulation of leukocyte activation;GO:0032769//negative regulation of monooxygenase activity;GO:0002237//response to molecule of bacterial origin;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0007186//G-protein coupled receptor signaling pathway" gi|157012011|ref|NP_034054.3|/0/cannabinoid receptor 2 [Mus musculus] 432769 2436 0.34 0.38 0.160464672 Up 0.116345105 Zfp708 zinc finger protein 708 K09228|1|0.0|1130|mmu:432769|KRAB domain-containing zinc finger protein - - - gi|133892592|ref|NP_001012325.2|/0/zinc finger protein 708 isoform a [Mus musculus] 378435 1080 0.32 0.356666667 0.156504486 Up 0.116345105 Mafa "v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)" K07595|1|2e-89|331|mmu:378435|transcription factor MAFA GO:0043231//intracellular membrane-bounded organelle GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity GO:0009746;GO:0019932//second-messenger-mediated signaling;GO:0030072//peptide hormone secretion;GO:0006366//transcription from RNA polymerase II promoter gi|34996509|ref|NP_919331.1|/2.00049e-88/transcription factor MafA [Mus musculus] 320981 3065 0.38 0.34 -0.160464672 Down 0.116345105 Enpp6 ectonucleotide pyrophosphatase/phosphodiesterase 6 K08743|1|0.0|905|mmu:320981|ectonucleotide pyrophosphatase/phosphodiesterase family member 6 [EC:3.1.4.-] GO:0031224//intrinsic component of membrane GO:0008081//phosphoric diester hydrolase activity GO:0006629//lipid metabolic process;GO:0042439//ethanolamine-containing compound metabolic process gi|28893409|ref|NP_796278.1|/0/ectonucleotide pyrophosphatase/phosphodiesterase family member 6 precursor [Mus musculus] 791383 1417 0.35 0.39 0.156119202 Up 0.116345105 Gm9962 predicted gene 9962 K05175|1|1e-21|107|mmu:110886|gamma-aminobutyric acid receptor subunit alpha GO:0043005//neuron projection;GO:0097060//synaptic membrane;GO:0043025//neuronal cell body;GO:0034702//ion channel complex GO:0005253//anion channel activity;GO:0005102//receptor binding;GO:0016917//GABA receptor activity;GO:0015276//ligand-gated ion channel activity GO:0007267//cell-cell signaling;GO:0050954//sensory perception of mechanical stimulus;GO:0007612//learning;GO:0021675//nerve development;GO:0015698//inorganic anion transport;GO:0048666//neuron development;GO:0002209//behavioral defense response;GO:0007186//G-protein coupled receptor signaling pathway "gi|148689915|gb|EDL21862.1|/4.31146e-71/mCG146224, partial [Mus musculus]" 12402 5083 0.316666667 0.353333333 0.158064846 Up 0.116345105 Cbl Casitas B-lineage lymphoma K04707|1|0.0|1727|mmu:12402|E3 ubiquitin-protein ligase CBL [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0005901//caveola GO:0046914//transition metal ion binding;GO:0060089;GO:0005102//receptor binding;GO:0019904//protein domain specific binding;GO:0019787//ubiquitin-like protein transferase activity GO:0009967//positive regulation of signal transduction;GO:0006915//apoptotic process;GO:0032446//protein modification by small protein conjugation gi|80978932|ref|NP_031645.2|/0/E3 ubiquitin-protein ligase CBL [Mus musculus] 108961 3705 0.406666667 0.363333333 -0.162553013 Down 0.116345105 E2f8 E2F transcription factor 8 K09391|1|0.0|1683|mmu:108961|transcription factor E2F7/8 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0042802//identical protein binding GO:0000278//mitotic cell cycle;GO:0001525//angiogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0032875//regulation of DNA endoreduplication;GO:0001889//liver development;GO:0000910//cytokinesis "gi|148691021|gb|EDL22968.1|/0/E2F transcription factor 8, partial [Mus musculus]" 210027 2784 0.756666667 0.706666667 -0.098628033 Down 0.116147655 Slc35f3 "solute carrier family 35, member F3" "K15288|1|0.0|708|mmu:210027|solute carrier family 35, member F3/4" GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization "gi|148679862|gb|EDL11809.1|/0/solute carrier family 35, member F3, isoform CRA_a, partial [Mus musculus]" 52855 3545.35 0.633333333 0.68 0.102569734 Up 0.116147655 Lair1 leukocyte-associated Ig-like receptor 1 K06725|1|1e-120|437|mmu:52855|leukocyte-associated Ig-like receptor GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148699259|gb|EDL31206.1|/1.32802e-126/leukocyte-associated Ig-like receptor 1, isoform CRA_b, partial [Mus musculus]" 19893 3171.16 0.833333333 0.78 -0.095419565 Down 0.116147655 Rpgr retinitis pigmentosa GTPase regulator K19607|1|1e-142|509|mmu:19893|X-linked retinitis pigmentosa GTPase regulator GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0005488//binding;GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0005488//binding GO:0010927;GO:0050953//sensory perception of light stimulus;GO:0001754//eye photoreceptor cell differentiation;GO:0010927;GO:0050953//sensory perception of light stimulus;GO:0001754//eye photoreceptor cell differentiation;GO:0010927;GO:0050953//sensory perception of light stimulus;GO:0001754//eye photoreceptor cell differentiation;GO:0010927;GO:0050953//sensory perception of light stimulus;GO:0001754//eye photoreceptor cell differentiation;GO:0010927;GO:0050953//sensory perception of light stimulus;GO:0001754//eye photoreceptor cell differentiation;GO:0010927;GO:0050953//sensory perception of light stimulus;GO:0001754//eye photoreceptor cell differentiation gi|6755348|ref|NP_035415.1|/0/X-linked retinitis pigmentosa GTPase regulator isoform 3 [Mus musculus] 22184 2971.76 3.81 3.913333333 0.038607005 Up 0.116110046 Zrsr2 "zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2" - GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0036002//pre-mRNA binding;GO:0046914//transition metal ion binding;GO:0036002//pre-mRNA binding "GO:0000398//mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome" "gi|49117387|gb|AAH65693.1|/1.40763e-68/Zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2 [Mus musculus]" 79202 4173 3.52 3.416666667 -0.042985925 Down 0.116110046 Tnfrsf22 "tumor necrosis factor receptor superfamily, member 22" K05158|1|8e-80|301|mmu:79202|tumor necrosis factor receptor superfamily member 22;K05159|2|4e-63|246|mmu:79201|tumor necrosis factor receptor superfamily member 23;K04722|4|1e-24|118|mze:101465040|tumor necrosis factor receptor superfamily member 10;K05161|5|7e-23|112|mmu:244237|tumor necrosis factor receptor superfamily member 26 GO:0016020//membrane GO:0005515//protein binding GO:0006915//apoptotic process "gi|82793635|ref|XP_728120.1|/4.0291e-146/RNase H, partial [Plasmodium yoelii yoelii 17XNL] " 26419 5709.21 3.686666667 3.786666667 0.038611449 Up 0.116110046 Mapk8 mitogen-activated protein kinase 8 K04440|1|0.0|773|hgl:101715259|c-Jun N-terminal kinase [EC:2.7.11.24] GO:0031981//nuclear lumen;GO:0030424//axon;GO:0030425//dendrite;GO:0044444//cytoplasmic part;GO:0043025//neuronal cell body;GO:0031981//nuclear lumen;GO:0030424//axon;GO:0030425//dendrite;GO:0044444//cytoplasmic part;GO:0043025//neuronal cell body;GO:0031981//nuclear lumen;GO:0030424//axon;GO:0030425//dendrite;GO:0044444//cytoplasmic part;GO:0043025//neuronal cell body GO:0030234//enzyme regulator activity;GO:0032550;GO:0019899//enzyme binding;GO:0016909//SAP kinase activity;GO:0030234//enzyme regulator activity;GO:0032550;GO:0019899//enzyme binding;GO:0016909//SAP kinase activity;GO:0030234//enzyme regulator activity;GO:0032550;GO:0019899//enzyme binding;GO:0016909//SAP kinase activity "GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006915//apoptotic process;GO:0009612//response to mechanical stimulus;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008104//protein localization;GO:0051094//positive regulation of developmental process;GO:0009967//positive regulation of signal transduction;GO:0016477//cell migration;GO:0009416//response to light stimulus;GO:0016575//histone deacetylation;GO:0051403//stress-activated MAPK cascade;GO:0031112;GO:0000302//response to reactive oxygen species;GO:0043393//regulation of protein binding;GO:0006260//DNA replication;GO:0009953//dorsal/ventral pattern formation;GO:0010038//response to metal ion;GO:0030030//cell projection organization;GO:0006468//protein phosphorylation;GO:0006355//regulation of transcription, DNA-templated;GO:0051345//positive regulation of hydrolase activity;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006915//apoptotic process;GO:0009612//response to mechanical stimulus;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008104//protein localization;GO:0051094//positive regulation of developmental process;GO:0009967//positive regulation of signal transduction;GO:0016477//cell migration;GO:0009416//response to light stimulus;GO:0016575//histone deacetylation;GO:0051403//stress-activated MAPK cascade;GO:0031112;GO:0000302//response to reactive oxygen species;GO:0043393//regulation of protein binding;GO:0006260//DNA replication;GO:0009953//dorsal/ventral pattern formation;GO:0010038//response to metal ion;GO:0030030//cell projection organization;GO:0006468//protein phosphorylation;GO:0006355//regulation of transcription, DNA-templated;GO:0051345//positive regulation of hydrolase activity;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006915//apoptotic process;GO:0009612//response to mechanical stimulus;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008104//protein localization;GO:0051094//positive regulation of developmental process;GO:0009967//positive regulation of signal transduction;GO:0016477//cell migration;GO:0009416//response to light stimulus;GO:0016575//histone deacetylation;GO:0051403//stress-activated MAPK cascade;GO:0031112;GO:0000302//response to reactive oxygen species;GO:0043393//regulation of protein binding;GO:0006260//DNA replication;GO:0009953//dorsal/ventral pattern formation;GO:0010038//response to metal ion;GO:0030030//cell projection organization;GO:0006468//protein phosphorylation;GO:0006355//regulation of transcription, DNA-templated;GO:0051345//positive regulation of hydrolase activity" "gi|148692907|gb|EDL24854.1|/0/mitogen activated protein kinase 8, isoform CRA_c, partial [Mus musculus]" 18166 3007 4.143333333 4.04 -0.036436598 Down 0.116110046 Npy1r neuropeptide Y receptor Y1 K04204|1|0.0|705|mmu:18166|neuropeptide Y receptor type 1 GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0030136//clathrin-coated vesicle GO:0004983//neuropeptide Y receptor activity GO:0003007//heart morphogenesis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0046879//hormone secretion;GO:0043627//response to estrogen;GO:0019229//regulation of vasoconstriction;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0019318//hexose metabolic process;GO:0014821;GO:0007600//sensory perception;GO:0035264//multicellular organism growth;GO:0044708//single-organism behavior gi|6754882|ref|NP_035064.1|/0/neuropeptide Y receptor type 1 [Mus musculus] 333639 3346 3.306666667 3.21 -0.042804323 Down 0.116110046 Mamld1 mastermind-like domain containing 1 K19512|1|0.0|1095|mmu:333639|mastermind-like domain-containing protein 1 - - "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|365777435|ref|NP_001074823.2|/0/mastermind-like domain-containing protein 1 isoform 1 [Mus musculus] 240442 4188 3.366666667 3.263333333 -0.044974528 Down 0.116110046 Adnp2 ADNP homeobox 2 K09228|1|9e-07|59.3|pxy:105388020|KRAB domain-containing zinc finger protein;K03006|2|6e-06|56.6|cmk:103184043|DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] GO:0044464 GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity GO:0030154//cell differentiation;GO:0006979//response to oxidative stress;GO:0016049//cell growth;GO:0008219//cell death;GO:0032526//response to retinoic acid gi|26006219|dbj|BAC41452.1|/0/mKIAA0863 protein [Mus musculus] 12835 9024 3.48 3.376666667 -0.043487538 Down 0.116110046 Col6a3 "collagen, type VI, alpha 3" "K06238|1|0.0|2467|mmu:12835|collagen, type VI, alpha" GO:0005578//proteinaceous extracellular matrix;GO:0005886//plasma membrane GO:0004866//endopeptidase inhibitor activity GO:0009746 "gi|148708135|gb|EDL40082.1|/0/mCG12867, isoform CRA_a [Mus musculus]" 67369 2100 3.94 3.836666667 -0.038342202 Down 0.116110046 Qpctl glutaminyl-peptide cyclotransferase-like K00683|1|0.0|728|mmu:67369|glutaminyl-peptide cyclotransferase [EC:2.3.2.5] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0046914//transition metal ion binding;GO:0016787//hydrolase activity;GO:0016755//transferase activity, transferring amino-acyl groups" GO:0018199 gi|31560195|ref|NP_080387.2|/0/glutaminyl-peptide cyclotransferase-like protein [Mus musculus] 69581 3367 3.433333333 3.536666667 0.042780319 Up 0.116110046 Rhou ras homolog family member U "K07865|1|2e-117|426|mmu:69581|Ras homolog gene family, member U" GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0005924//cell-substrate adherens junction;GO:0012505//endomembrane system;GO:0044444//cytoplasmic part GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0043169//cation binding GO:0007010//cytoskeleton organization;GO:0007265//Ras protein signal transduction;GO:0022604//regulation of cell morphogenesis;GO:0044772//mitotic cell cycle phase transition;GO:0009154//purine ribonucleotide catabolic process gi|19923060|ref|NP_598716.1|/1.51871e-116/rho-related GTP-binding protein RhoU [Mus musculus] 66234 1824 3.706666667 3.803333333 0.037142004 Up 0.116110046 Msmo1 methylsterol monoxygenase 1 K07750|1|1e-179|632|mmu:66234|methylsterol monooxygenase [EC:1.14.13.72] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane "GO:0046914//transition metal ion binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen" GO:0006631//fatty acid metabolic process;GO:0006694//steroid biosynthetic process;GO:0008203//cholesterol metabolic process gi|13384836|ref|NP_079712.1|/1.14416e-178/methylsterol monooxygenase 1 [Mus musculus] 69274 4627 3.21 3.306666667 0.042804323 Up 0.116110046 Ctdspl "CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like" K15731|1|8e-158|561|mmu:69274|carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16] GO:0043231//intracellular membrane-bounded organelle GO:0016791//phosphatase activity;GO:0043169//cation binding - "gi|148677300|gb|EDL09247.1|/7.32105e-157/CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like, partial [Mus musculus]" 235300 3500 3.373333333 3.27 -0.044884248 Down 0.116110046 Tmem136 transmembrane protein 136 - GO:0031224//intrinsic component of membrane - - "gi|148693601|gb|EDL25548.1|/1.61588e-161/mCG1534, partial [Mus musculus]" 17385 2089.99 3.516666667 3.42 -0.040212268 Down 0.116110046 Mmp11 matrix metallopeptidase 11 K07993|1|0.0|985|mmu:17385|matrix metalloproteinase-11 (stromelysin 3) [EC:3.4.24.-] GO:0031012//extracellular matrix;GO:0031012//extracellular matrix GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding GO:0019538//protein metabolic process;GO:0032963//collagen metabolic process;GO:0019538//protein metabolic process;GO:0032963//collagen metabolic process gi|6678894|ref|NP_032632.1|/0/stromelysin-3 preproprotein [Mus musculus] 194952 4435.86 3.383333333 3.48 0.040641984 Up 0.116110046 Jmjd4 jumonji domain containing 4 K17500|1|3e-66|256|smm:Smp_147870|integrin-linked kinase-associated serine/threonine phosphatase 2C [EC:3.1.3.16];K11323|2|4e-20|103|dwi:Dwil_GK14253|histone arginine demethylase JMJD6 [EC:1.14.11.-] - - - gi|30520031|ref|NP_848774.1|/0/jmjC domain-containing protein 4 isoform 1 [Mus musculus] 94191 4375 3.943333333 4.043333333 0.036129477 Up 0.116110046 Adarb2 "adenosine deaminase, RNA-specific, B2" K13194|1|0.0|1255|mmu:94191|double stranded RNA-specific editase B [EC:3.5.-.-] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0043169//cation binding;GO:0003723//RNA binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0043169//cation binding;GO:0003723//RNA binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0043169//cation binding;GO:0003723//RNA binding;GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines" GO:0006396//RNA processing;GO:0006396//RNA processing;GO:0006396//RNA processing gi|31542106|ref|NP_443209.2|/0/double-stranded RNA-specific editase B2 isoform 1 [Mus musculus] 64291 2905.29 25.97666667 25.63 -0.019382837 Down 0.115997217 Osbpl1a oxysterol binding protein-like 1A K20174|1|0.0|989|mmu:64291|oxysterol-binding protein-related protein 1/2 GO:0005768//endosome;GO:0005768//endosome;GO:0005768//endosome;GO:0005768//endosome;GO:0005768//endosome;GO:0005764//lysosome;GO:0031981//nuclear lumen;GO:0005768//endosome;GO:0005768//endosome GO:0032934//sterol binding;GO:0032934//sterol binding;GO:0032934//sterol binding;GO:0032934//sterol binding;GO:0032934//sterol binding;GO:0032934//sterol binding;GO:0032934//sterol binding GO:0051234//establishment of localization;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0010876//lipid localization;GO:0006810//transport;GO:0002478;GO:0016125//sterol metabolic process;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0010876//lipid localization gi|357394760|ref|NP_001239418.1|/0/oxysterol-binding protein-related protein 1 isoform 2 [Mus musculus] 16456 2482 23.02333333 22.67333333 -0.022100218 Down 0.115997217 F11r F11 receptor K06089|1|3e-157|558|mmu:16456|junctional adhesion molecule 1 GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane - GO:0030154//cell differentiation;GO:0022610 "gi|148707131|gb|EDL39078.1|/1.19875e-168/F11 receptor, partial [Mus musculus]" 98766 3450 24.15666667 24.50666667 0.020752872 Up 0.115997217 Ubac1 ubiquitin associated domain containing 1 K12174|1|0.0|682|mmu:98766|Kip1 ubiquitination-promoting complex protein 2 GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0032446//protein modification by small protein conjugation gi|260447056|ref|NP_598596.2|/0/ubiquitin-associated domain-containing protein 1 [Mus musculus] 78774 1561 0.38 0.343333333 -0.146389487 Down 0.1159314 Cfap61 cilia and flagella associated protein 61 K06756|1|1e-57|226|bfo:BRAFLDRAFT_120092|neuronal cell adhesion molecule - - - gi|110630012|ref|NP_780489.2|/1.00305e-156/cilia- and flagella-associated protein 61 [Mus musculus] 332359 2147 0.36 0.4 0.152003093 Up 0.1159314 Tigd3 tigger transposable element derived 3 K11496|1|7e-34|148|ngi:103743119|centromere protein B GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding - "gi|148701235|gb|EDL33182.1|/0/tigger transposable element derived 3, isoform CRA_a, partial [Mus musculus]" 246229 3571 2.316666667 2.396666667 0.048978793 Up 0.115874986 Bivm "basic, immunoglobulin-like variable motif containing" K10846|1|0.0|848|ngi:103751657|DNA excision repair protein ERCC-5 GO:0043231//intracellular membrane-bounded organelle - - gi|568906399|ref|XP_006496061.1|/0/PREDICTED: basic immunoglobulin-like variable motif-containing protein isoform X2 [Mus musculus] 28042 6769 2.27 2.19 -0.051761428 Down 0.115874986 Ept1 ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific) K00993|1|0.0|717|mmu:28042|ethanolaminephosphotransferase [EC:2.7.8.1] - - - - 54338 6487 2.61 2.693333333 0.045342985 Up 0.115874986 Slc23a2 "solute carrier family 23 (nucleobase transporters), member 2" "K14611|1|0.0|1164|mmu:54338|solute carrier family 23 (nucleobase transporter), member 1/2" GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0044424 GO:0015370//solute:sodium symporter activity;GO:0051183//vitamin transporter activity;GO:0015145//monosaccharide transmembrane transporter activity GO:0006814//sodium ion transport;GO:0015882//L-ascorbic acid transport;GO:0044763;GO:0005996//monosaccharide metabolic process;GO:0006950//response to stress gi|42741688|ref|NP_061294.2|/0/solute carrier family 23 member 2 [Mus musculus] 97487 7734 2.596666667 2.68 0.045572173 Up 0.115874986 Cmtm4 CKLF-like MARVEL transmembrane domain containing 4 - GO:0031224//intrinsic component of membrane;GO:0044421 GO:0005102//receptor binding GO:0042221//response to chemical gi|27312023|ref|NP_705810.2|/1.46636e-104/CKLF-like MARVEL transmembrane domain-containing protein 4 [Mus musculus] 22661 9431 2.373333333 2.293333333 -0.049468676 Down 0.115874986 Zfp148 zinc finger protein 148 K09228|1|1e-29|136|gja:107122611|KRAB domain-containing zinc finger protein GO:0031981//nuclear lumen GO:0044212//transcription regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0043566//structure-specific DNA binding GO:0019953//sexual reproduction;GO:0065003;GO:0006366//transcription from RNA polymerase II promoter gi|6756049|ref|NP_035879.1|/0/zinc finger protein 148 [Mus musculus] 77044 9029 2.37 2.45 0.04789469 Up 0.115874986 Arid2 "AT rich interactive domain 2 (ARID, RFX-like)" K11765|1|0.0|3273|mmu:77044|AT-rich interactive domain-containing protein 2 GO:0044464 GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated;GO:0034728//nucleosome organization" gi|262231796|ref|NP_780460.3|/0/AT-rich interactive domain-containing protein 2 [Mus musculus] 243864 1120 2.223333333 2.3 0.0489096 Up 0.115874986 Mill2 MHC I like leukocyte 2 K07985|1|4e-39|164|mcc:100141395|MHC class I-related protein - - - - 53614 4450 2.21 2.133333333 -0.050936965 Down 0.115874986 Reck reversion-inducing-cysteine-rich protein with kazal motifs K17461|1|0.0|1891|mmu:53614|reversion-inducing-cysteine-rich protein with kazal motifs GO:0031224//intrinsic component of membrane GO:0004866//endopeptidase inhibitor activity GO:0043062//extracellular structure organization;GO:0010466//negative regulation of peptidase activity;GO:0001568//blood vessel development gi|172072643|ref|NP_057887.2|/0/reversion-inducing cysteine-rich protein with Kazal motifs precursor [Mus musculus] 20128 3771 2.69 2.606666667 -0.045400066 Down 0.115874986 Trim30a tripartite motif-containing 30A K10648|1|0.0|669|rno:499223|tripartite motif-containing protein 5 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated;GO:0001818//negative regulation of cytokine production;GO:0002224//toll-like receptor signaling pathway;GO:0031333//negative regulation of protein complex assembly;GO:0016567//protein ubiquitination;GO:0072593//reactive oxygen species metabolic process;GO:0009896" gi|12407363|gb|AAG53470.1|/0/tripartite motif protein [Mus musculus] 214552 5504 2.516666667 2.436666667 -0.046605238 Down 0.115874986 Cep164 centrosomal protein 164 K16462|1|0.0|1868|mmu:214552|centrosomal protein CEP164 GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0044446 - - gi|160420304|ref|NP_001074842.2|/0/centrosomal protein of 164 kDa [Mus musculus] 381903 2002 2.146666667 2.223333333 0.050626073 Up 0.115874986 Alg8 "asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase)" "K03849|1|0.0|971|mmu:381903|alpha-1,3-glucosyltransferase [EC:2.4.1.265]" GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0000030//mannosyltransferase activity GO:0006486//protein glycosylation "gi|38512072|gb|AAH61244.1|/0/Asparagine-linked glycosylation 8 homolog (yeast, alpha-1,3-glucosyltransferase) [Mus musculus]" 68475 864 20.84 21.17666667 0.023120241 Up 0.115780962 Ssna1 SS nuclear autoantigen 1 K16780|1|4e-53|210|ngi:103732601|sjoegren syndrome nuclear autoantigen 1 GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005515//protein binding GO:0007224//smoothened signaling pathway;GO:0044772//mitotic cell cycle phase transition;GO:0010970//transport along microtubule gi|26382599|dbj|BAB22733.2|/2.28291e-67/unnamed protein product [Mus musculus] 12499 4947.11 26.64 26.3 -0.018531283 Down 0.115780962 Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 K01511|1|0.0|865|mmu:12499|ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0017110//nucleoside-diphosphatase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0017110//nucleoside-diphosphatase activity GO:0006007//glucose catabolic process;GO:0040007//growth;GO:0009966//regulation of signal transduction;GO:0006486//protein glycosylation;GO:0006458//'de novo' protein folding;GO:0009150//purine ribonucleotide metabolic process;GO:0006007//glucose catabolic process;GO:0040007//growth;GO:0009966//regulation of signal transduction;GO:0006486//protein glycosylation;GO:0006458//'de novo' protein folding;GO:0009150//purine ribonucleotide metabolic process;GO:0006007//glucose catabolic process;GO:0040007//growth;GO:0009966//regulation of signal transduction;GO:0006486//protein glycosylation;GO:0006458//'de novo' protein folding;GO:0009150//purine ribonucleotide metabolic process;GO:0006007//glucose catabolic process;GO:0040007//growth;GO:0009966//regulation of signal transduction;GO:0006486//protein glycosylation;GO:0006458//'de novo' protein folding;GO:0009150//purine ribonucleotide metabolic process "gi|148670847|gb|EDL02794.1|/0/ectonucleoside triphosphate diphosphohydrolase 5, isoform CRA_c, partial [Mus musculus]" 66849 4098 26.69666667 27.03333333 0.018079795 Up 0.115780962 Ppp1r2 "protein phosphatase 1, regulatory (inhibitor) subunit 2" K16833|1|5e-95|352|mmu:66849|protein phosphatase inhibitor 2 - GO:0019212//phosphatase inhibitor activity GO:0010921//regulation of phosphatase activity;GO:0006073//cellular glucan metabolic process;GO:0007165//signal transduction;GO:0044092//negative regulation of molecular function gi|18859587|ref|NP_080076.1|/4.5249e-94/protein phosphatase inhibitor 2 [Mus musculus] 67087 2686 19.55666667 19.89333333 0.024624544 Up 0.115780962 Ctnnbip1 catenin beta interacting protein 1 K04493|1|7e-45|159|ggo:101147518|Beta-catenin-interacting protein 1 (Inhibitor of beta-catenin and Tcf-4) - - - gi|826345313|ref|XP_012518023.1|/4.95857e-40/PREDICTED: beta-catenin-interacting protein 1 isoform X1 [Propithecus coquereli] 226026 5748.19 1.686666667 1.753333333 0.055925415 Up 0.115743353 Smc5 structural maintenance of chromosomes 5 K20478|1|4e-14|84.3|dre:557772|golgin subfamily B member 1 GO:0044427;GO:0016604//nuclear body;GO:0000793//condensed chromosome;GO:0044427;GO:0016604//nuclear body;GO:0000793//condensed chromosome;GO:0044427;GO:0016604//nuclear body;GO:0000793//condensed chromosome GO:0032550;GO:0032550;GO:0032550 GO:0000725//recombinational repair;GO:0007569//cell aging;GO:0034088//maintenance of mitotic sister chromatid cohesion;GO:0000723//telomere maintenance;GO:0007091//metaphase/anaphase transition of mitotic cell cycle;GO:0000725//recombinational repair;GO:0007569//cell aging;GO:0034088//maintenance of mitotic sister chromatid cohesion;GO:0000723//telomere maintenance;GO:0007091//metaphase/anaphase transition of mitotic cell cycle;GO:0000725//recombinational repair;GO:0007569//cell aging;GO:0034088//maintenance of mitotic sister chromatid cohesion;GO:0000723//telomere maintenance;GO:0007091//metaphase/anaphase transition of mitotic cell cycle "gi|148709653|gb|EDL41599.1|/0/mCG5312, isoform CRA_b, partial [Mus musculus]" 103768 1777 1.736666667 1.666666667 -0.059355278 Down 0.115743353 Tubg2 "tubulin, gamma 2" K10389|1|0.0|843|ocu:100351097|tubulin gamma GO:0005874//microtubule;GO:0005813//centrosome;GO:0005819//spindle GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0009154//purine ribonucleotide catabolic process;GO:0044763;GO:0043623//cellular protein complex assembly gi|655871442|ref|XP_002719451.2|/0/PREDICTED: LOW QUALITY PROTEIN: tubulin gamma-2 chain-like [Oryctolagus cuniculus] 54004 8456 1.766666667 1.693333333 -0.061163863 Down 0.115743353 Diaph2 diaphanous related formin 2 K05741|1|0.0|993|mmu:54004|diaphanous 2 - GO:0017016//Ras GTPase binding GO:0007292//female gamete generation;GO:0048869//cellular developmental process;GO:0008154//actin polymerization or depolymerization gi|189491671|ref|NP_766081.1|/0/protein diaphanous homolog 2 [Mus musculus] 170755 5398 1.916666667 1.843333333 -0.056282476 Down 0.115743353 Sgk3 serum/glucocorticoid regulated kinase 3 K13304|1|0.0|1018|mmu:170755|serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1] GO:0031982//vesicle;GO:0005768//endosome;GO:0031982//vesicle;GO:0005768//endosome;GO:0031982//vesicle;GO:0005768//endosome GO:0032550;GO:0004672//protein kinase activity;GO:0005543//phospholipid binding;GO:0016247//channel regulator activity;GO:0032550;GO:0004672//protein kinase activity;GO:0005543//phospholipid binding;GO:0016247//channel regulator activity;GO:0032550;GO:0004672//protein kinase activity;GO:0005543//phospholipid binding;GO:0016247//channel regulator activity "GO:0006355//regulation of transcription, DNA-templated;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0006796//phosphate-containing compound metabolic process;GO:0050896//response to stimulus;GO:0006464//cellular protein modification process;GO:0016049//cell growth;GO:0016477//cell migration;GO:0006355//regulation of transcription, DNA-templated;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0006796//phosphate-containing compound metabolic process;GO:0050896//response to stimulus;GO:0006464//cellular protein modification process;GO:0016049//cell growth;GO:0016477//cell migration;GO:0006355//regulation of transcription, DNA-templated;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0006796//phosphate-containing compound metabolic process;GO:0050896//response to stimulus;GO:0006464//cellular protein modification process;GO:0016049//cell growth;GO:0016477//cell migration" gi|18959280|ref|NP_573483.1|/0/serine/threonine-protein kinase Sgk3 [Mus musculus] 102124 1307 1.633333333 1.566666667 -0.060120992 Down 0.115743353 Enkd1 enkurin domain containing 1 K08396|1|2e-08|62.8|cfa:485410|Mas-related G protein-coupled receptor member X GO:0005874//microtubule - - gi|38142470|ref|NP_938041.1|/9.21934e-174/enkurin domain-containing protein 1 [Mus musculus] 194268 2942 1.773333333 1.703333333 -0.058102955 Down 0.115743353 9930104L06Rik RIKEN cDNA 9930104L06 gene - - - - gi|114145557|ref|NP_808241.2|/6.93937e-102/uncharacterized protein C1orf109 homolog [Mus musculus] 102294 2930 1.94 1.866666667 -0.055592326 Down 0.115743353 Cyp4v3 "cytochrome P450, family 4, subfamily v, polypeptide 3" "K07427|1|0.0|969|mmu:102294|cytochrome P450, family 4, subfamily V" GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016491//oxidoreductase activity GO:0050953//sensory perception of light stimulus;GO:0019395//fatty acid oxidation gi|19527190|ref|NP_598730.1|/0/cytochrome P450 4V2 [Mus musculus] 246103 6870 1.63 1.696666667 0.057831191 Up 0.115743353 Atxn7 ataxin 7 K11318|1|0.0|1311|mmu:246103|ataxin-7 - - - - 73635 1461 19.31333333 18.98333333 -0.024863843 Down 0.115508293 Ptges3l prostaglandin E synthase 3 (cytosolic)-like K07050|1|7e-59|230|fab:101821562|misacylated tRNA(Ala) deacylase [EC:3.1.1.-] - - - gi|914903135|ref|XP_013212436.1|/3.36539e-76/PREDICTED: LOW QUALITY PROTEIN: putative protein PTGES3L [Ictidomys tridecemlineatus] 107508 4850 20.59333333 20.27 -0.022831281 Down 0.115263831 Eprs glutamyl-prolyl-tRNA synthetase K14163|1|0.0|2902|mmu:107508|bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15] - - - gi|82617575|ref|NP_084011.1|/0/bifunctional glutamate/proline--tRNA ligase [Mus musculus] 217365 4685 27.79333333 27.47 -0.016881961 Down 0.115263831 Nploc4 "NPL4 homolog, ubiquitin recognition factor" K14015|1|0.0|1221|mmu:217365|nuclear protein localization protein 4 homolog GO:0005789//endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0032182//ubiquitin-like protein binding;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0032182//ubiquitin-like protein binding GO:0006996//organelle organization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006996//organelle organization;GO:0006511//ubiquitin-dependent protein catabolic process gi|37360414|dbj|BAC98185.1|/0/mKIAA1499 protein [Mus musculus] 19062 2660 19.16 18.83666667 -0.024553873 Down 0.115263831 Inpp5k inositol polyphosphate 5-phosphatase K "K01106|1|0.0|931|mmu:19062|inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56]" GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0001726//ruffle;GO:0016020//membrane GO:0008528//G-protein coupled peptide receptor activity;GO:0034594//phosphatidylinositol trisphosphate phosphatase activity;GO:0046030//inositol trisphosphate phosphatase activity;GO:0052743 "GO:0005978//glycogen biosynthetic process;GO:0043405//regulation of MAP kinase activity;GO:0035809;GO:0030031//cell projection assembly;GO:0032232//negative regulation of actin filament bundle assembly;GO:0006351//transcription, DNA-templated;GO:0001933//negative regulation of protein phosphorylation;GO:0090313;GO:0046488//phosphatidylinositol metabolic process;GO:0070849//response to epidermal growth factor;GO:0033500//carbohydrate homeostasis;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0051348//negative regulation of transferase activity;GO:0010827//regulation of glucose transport;GO:0051591//response to cAMP;GO:0045071//negative regulation of viral genome replication;GO:0006816//calcium ion transport;GO:0034612//response to tumor necrosis factor;GO:0032897//negative regulation of viral transcription;GO:0008286//insulin receptor signaling pathway;GO:0003097//renal water transport" gi|6679449|ref|NP_032942.1|/0/inositol polyphosphate 5-phosphatase K [Mus musculus] 21399 2726.99 19.03 19.34666667 0.023809457 Up 0.115263831 Tcea1 transcription elongation factor A (SII) 1 K03145|1|4e-151|538|cjc:100409444|transcription elongation factor S-II GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0046914//transition metal ion binding;GO:0008135//translation factor activity, RNA binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding" "GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006412//translation;GO:0044764;GO:0006289//nucleotide-excision repair;GO:0030099//myeloid cell differentiation;GO:0006354//DNA-templated transcription, elongation;GO:0006354//DNA-templated transcription, elongation;GO:0030099//myeloid cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006354//DNA-templated transcription, elongation;GO:0030099//myeloid cell differentiation;GO:0006366//transcription from RNA polymerase II promoter" gi|229094714|ref|NP_001153223.1|/2.26544e-157/transcription elongation factor A protein 1 isoform 1 [Mus musculus] 68117 1346.18 29.67333333 29.35333333 -0.015642657 Down 0.115263831 Apool apolipoprotein O-like - - - - - 20462 2135 18.86 19.18 0.024273044 Up 0.115263831 Tra2b transformer 2 beta homolog (Drosophila) K12897|1|7e-61|226|ocu:100353793|transformer-2 protein GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding "GO:0006979//response to oxidative stress;GO:0000380//alternative mRNA splicing, via spliceosome" gi|655853685|ref|XP_008264802.1|/5.81861e-60/PREDICTED: LOW QUALITY PROTEIN: transformer-2 protein homolog beta [Oryctolagus cuniculus] 80385 1661 28.64666667 28.33 -0.016036675 Down 0.115263831 Tusc2 tumor suppressor candidate 2 K09850|1|5e-24|115|fch:102049227|Ras association domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle - GO:0006952//defense response;GO:0030098//lymphocyte differentiation;GO:0032602//chemokine production;GO:0042391//regulation of membrane potential;GO:0031323//regulation of cellular metabolic process;GO:0021700//developmental maturation gi|940781628|ref|XP_006108255.2|/4.89216e-48/PREDICTED: tumor suppressor candidate 2 [Myotis lucifugus] 244654 4733 19.57666667 19.9 0.023633294 Up 0.115263831 Mtss1l metastasis suppressor 1-like K20128|1|0.0|1116|mmu:244654|metastasis suppressor protein 1 - "GO:0030674//protein binding, bridging;GO:0019904//protein domain specific binding;GO:0030674//protein binding, bridging;GO:0019904//protein domain specific binding" GO:0030031//cell projection assembly;GO:0007154//cell communication;GO:0030031//cell projection assembly;GO:0007154//cell communication gi|38348492|ref|NP_941027.1|/0/MTSS1-like protein isoform 1 [Mus musculus] 76686 3300 5.51 5.383333333 -0.03355256 Down 0.115226221 Clip3 CAP-GLY domain containing linker protein 3 K10423|1|0.0|938|rno:308493|CAP-Gly domain-containing linker protein 3/4 GO:0005802//trans-Golgi network;GO:0044425;GO:0005769//early endosome;GO:0010008//endosome membrane GO:0043208//glycosphingolipid binding;GO:0015631//tubulin binding GO:0018231;GO:0051130//positive regulation of cellular component organization;GO:0010827//regulation of glucose transport;GO:0015031//protein transport;GO:0006915//apoptotic process;GO:0044085;GO:0001932//regulation of protein phosphorylation;GO:0006897//endocytosis;GO:0030154//cell differentiation;GO:0031111//negative regulation of microtubule polymerization or depolymerization gi|958686651|ref|XP_014693788.1|/0/PREDICTED: CAP-Gly domain-containing linker protein 3 isoform X1 [Equus asinus] 72008 1941 7.116666667 6.99 -0.025909208 Down 0.115226221 Zfyve19 "zinc finger, FYVE domain containing 19" K12182|1|2e-07|60.5|sko:100378364|hepatocyte growth factor-regulated tyrosine kinase substrate - GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - "gi|148695995|gb|EDL27942.1|/0/zinc finger, FYVE domain containing 19, isoform CRA_a, partial [Mus musculus]" 231003 3014 6.526666667 6.653333333 0.027730956 Up 0.115226221 Klhl17 kelch-like 17 K10454|1|0.0|1140|rno:246757|kelch-like protein 17 (actinfilin) GO:0005856//cytoskeleton;GO:0044297//cell body;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane GO:0003779//actin binding;GO:0019904//protein domain specific binding GO:0007417//central nervous system development;GO:0032446//protein modification by small protein conjugation;GO:0007010//cytoskeleton organization gi|21728394|ref|NP_663704.1|/0/kelch-like protein 17 [Rattus norvegicus] 20448 3874.2 6.676666667 6.546666667 -0.028367491 Down 0.115226221 St6galnac4 "ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4" "K03374|1|3e-151|539|mmu:20448|N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7D) [EC:2.4.99.7]" GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane GO:0008373//sialyltransferase activity;GO:0008373//sialyltransferase activity GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process "gi|21759447|sp|Q9R2B6.1|SIA7D_MOUSE/6.23481e-169/RecName: Full=Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase; AltName: Full=NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase; AltName: Full=ST6GalNAc IV; Short=ST6GalNAcIV; AltName: Full=Sialyltransferase 7D; Short=SIAT7-D" 72102 6445 6.186666667 6.313333333 0.02923962 Up 0.115226221 Dusp11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) K14165|1|1e-178|630|mmu:72102|atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] GO:0043231//intracellular membrane-bounded organelle GO:0004721//phosphoprotein phosphatase activity GO:0010467//gene expression;GO:0006470//protein dephosphorylation gi|294459958|ref|NP_082375.4|/1.07498e-177/RNA/RNP complex-1-interacting phosphatase [Mus musculus] 74198 2580.2 6.03 6.163333333 0.031552817 Up 0.115226221 Dtx2 "deltex 2, E3 ubiquitin ligase" K06058|1|0.0|1190|mmu:74198|deltex [EC:2.3.2.27] - - - - 277396 4621 6.926666667 6.793333333 -0.028041603 Down 0.115226221 Klhl23 kelch-like 23 K10460|1|0.0|1170|mmu:277396|kelch-like protein 23 - - - "gi|148695100|gb|EDL27047.1|/0/kelch-like 23 (Drosophila), isoform CRA_a, partial [Mus musculus]" 236794 4920 5.356666667 5.483333333 0.033717655 Up 0.115226221 Slc9a6 "solute carrier family 9 (sodium/hydrogen exchanger), member 6" "K12041|1|0.0|1275|mmu:236794|solute carrier family 9 (sodium/hydrogen exchanger), member 6/7" GO:0031224//intrinsic component of membrane;GO:0005769//early endosome;GO:0010008//endosome membrane GO:0005451//monovalent cation:proton antiporter activity GO:0044763;GO:0055067;GO:0030001//metal ion transport "gi|148710204|gb|EDL42150.1|/0/solute carrier family 9 (sodium/hydrogen exchanger), isoform 6, isoform CRA_b, partial [Mus musculus]" 20908 3159.91 6.07 5.943333333 -0.030424219 Down 0.115226221 Stx3 syntaxin 3 K08486|1|4e-142|508|rno:81802|syntaxin 1B/2/3 GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0030141//secretory granule;GO:0043234//protein complex;GO:0043005//neuron projection;GO:0044459;GO:0005766;GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0030141//secretory granule;GO:0043234//protein complex;GO:0043005//neuron projection;GO:0044459;GO:0005766;GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0030141//secretory granule;GO:0043234//protein complex;GO:0043005//neuron projection;GO:0044459;GO:0005766;GO:0031224//intrinsic component of membrane;GO:0030054//cell junction;GO:0030141//secretory granule;GO:0043234//protein complex;GO:0043005//neuron projection;GO:0044459;GO:0005766 GO:0050542;GO:0005515//protein binding;GO:0050542;GO:0005515//protein binding;GO:0050542;GO:0005515//protein binding;GO:0050542;GO:0005515//protein binding GO:0006979//response to oxidative stress;GO:0030030//cell projection organization;GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport;GO:0006979//response to oxidative stress;GO:0030030//cell projection organization;GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport;GO:0006979//response to oxidative stress;GO:0030030//cell projection organization;GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport;GO:0006979//response to oxidative stress;GO:0030030//cell projection organization;GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport gi|70778802|ref|NP_001020478.1|/4.68389e-138/syntaxin-3 isoform B [Mus musculus] 18933 4878.4 6.653333333 6.52 -0.02920535 Down 0.115226221 Prrx1 paired related homeobox 1 K09329|1|7e-124|448|lve:103073867|paired mesoderm homeobox protein GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0019904//protein domain specific binding;GO:0003677//DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0035108//limb morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0007224//smoothened signaling pathway;GO:0042471//ear morphogenesis;GO:0048514//blood vessel morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0035108//limb morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0007224//smoothened signaling pathway;GO:0042471//ear morphogenesis;GO:0048514//blood vessel morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0035108//limb morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0007224//smoothened signaling pathway;GO:0042471//ear morphogenesis;GO:0048514//blood vessel morphogenesis;GO:0048704//embryonic skeletal system morphogenesis gi|989911078|ref|XP_015441751.1|/2.68417e-107/PREDICTED: paired mesoderm homeobox protein 1 isoform X2 [Pteropus alecto] 56070 4403.83 5.693333333 5.56 -0.034188686 Down 0.115226221 Tcerg1 transcription elongation regulator 1 (CA150) K12824|1|0.0|870|mmu:56070|transcription elongation regulator 1 GO:0034399//nuclear periphery;GO:0034399//nuclear periphery GO:0001085//RNA polymerase II transcription factor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0001104//RNA polymerase II transcription cofactor activity "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|913501014|ref|XP_013205008.1|/0/PREDICTED: transcription elongation regulator 1 isoform X3 [Microtus ochrogaster] 74038 4240.58 5.853333333 5.726666667 -0.031562808 Down 0.115226221 Brip1os "BRCA1 interacting protein C-terminal helicase 1, opposite strand" K15164|1|6e-46|117|mmu:327987|mediator of RNA polymerase II transcription subunit 13 - - - - 112403 1447 6.42 6.553333333 0.029655618 Up 0.115226221 Dxo decapping exoribonuclease K14845|1|0.0|810|mmu:112403|RAT1-interacting protein - GO:0043169//cation binding;GO:0043169//cation binding - gi|254939704|ref|NP_291091.2|/0/decapping and exoribonuclease protein [Mus musculus] 78655 2434 23.43 23.73666667 0.018760398 Up 0.115094588 Eif3j1 "eukaryotic translation initiation factor 3, subunit J1" K03245|1|7e-83|311|mmu:78655|translation initiation factor 3 subunit J - - - gi|124244040|ref|NP_653128.2|/6.37565e-82/eukaryotic translation initiation factor 3 subunit J [Mus musculus] 100504616 2973 0.19 0.16 -0.247927513 Down 0.115094588 Gm15910 predicted gene 15910 - - - - - 67163 3270 21.85 21.53666667 -0.020838305 Down 0.115094588 Ccdc47 coiled-coil domain containing 47 - GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0006984//ER-nucleus signaling pathway;GO:0055065//metal ion homeostasis;GO:0007275//multicellular organism development "gi|148702331|gb|EDL34278.1|/0/mCG3218, isoform CRA_b, partial [Mus musculus]" 66659 1756 19.88 20.19 0.022323154 Up 0.115094588 Acp6 "acid phosphatase 6, lysophosphatidic" K14395|1|0.0|825|mmu:66659|lysophosphatidic acid phosphatase type 6 [EC:3.1.3.2] GO:0043231//intracellular membrane-bounded organelle GO:0016791//phosphatase activity - gi|66773165|ref|NP_062774.2|/0/lysophosphatidic acid phosphatase type 6 precursor [Mus musculus] 194590 7698 0.17 0.143333333 -0.246160587 Down 0.115094588 Reps2 RALBP1 associated Eps domain containing protein 2 K20068|1|0.0|1013|mmu:194590|RalBP1-associated Eps domain-containing protein GO:0044424;GO:0044424 GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0006897//endocytosis;GO:0006897//endocytosis gi|84490401|ref|NP_839987.2|/0/ralBP1-associated Eps domain-containing protein 2 isoform 1 [Mus musculus] 68879 3071 20.66666667 20.36 -0.021568153 Down 0.115094588 Prpf6 pre-mRNA splicing factor 6 K12855|1|0.0|1739|mmu:68879|pre-mRNA-processing factor 6 - - - - 103784 3431 29.81 30.12333333 0.015085047 Up 0.115094588 Wdr92 WD repeat domain 92 K14841|1|3e-06|57.4|tad:TRIADDRAFT_57177|ribosome biogenesis protein NSA1;K13175|2|3e-06|57.4|spu:580431|THO complex subunit 6 - GO:0042393//histone binding GO:0016571//histone methylation;GO:0012501//programmed cell death gi|148708735|gb|EDL40682.1|/0/mCG1050441 [Mus musculus] 71914 3776 26.95666667 26.65 -0.016506578 Down 0.115094588 Antxr2 anthrax toxin receptor 2 "K16628|1|9e-09|65.9|ola:101170175|collagen, type VII, alpha;K06238|2|1e-08|65.5|mze:105940696|collagen, type VI, alpha" GO:0031224//intrinsic component of membrane GO:0043169//cation binding GO:0000003//reproduction gi|50355939|ref|NP_598499.1|/0/anthrax toxin receptor 2 precursor [Mus musculus] 83672 1504 0.156666667 0.186666667 0.25276607 Up 0.115094588 Sytl3 synaptotagmin-like 3 K17598|1|0.0|947|mmu:83672|synaptotagmin-like protein GO:0019898//extrinsic component of membrane;GO:0019898//extrinsic component of membrane;GO:0019898//extrinsic component of membrane GO:0046914//transition metal ion binding;GO:0017016//Ras GTPase binding;GO:0005543//phospholipid binding;GO:0046914//transition metal ion binding;GO:0017016//Ras GTPase binding;GO:0005543//phospholipid binding;GO:0046914//transition metal ion binding;GO:0017016//Ras GTPase binding;GO:0005543//phospholipid binding GO:0016192//vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0015031//protein transport gi|13878233|ref|NP_113572.1|/0/synaptotagmin-like protein 3 isoform a [Mus musculus] 106298 3607 23.57666667 23.26333333 -0.01930193 Down 0.115094588 Rrn3 RRN3 RNA polymerase I transcription factor homolog (yeast) K15216|1|0.0|1188|mmu:106298|RNA polymerase I-specific transcription initiation factor RRN3 GO:0031981//nuclear lumen GO:0019899//enzyme binding "GO:0006915//apoptotic process;GO:0006355//regulation of transcription, DNA-templated;GO:0022613//ribonucleoprotein complex biogenesis;GO:0006360//transcription from RNA polymerase I promoter;GO:0042592//homeostatic process;GO:0006997//nucleus organization" gi|87299630|ref|NP_001034610.1|/0/RNA polymerase I-specific transcription initiation factor RRN3 [Mus musculus] 240754 2273 0.173333333 0.206666667 0.253756592 Up 0.115094588 Lax1 lymphocyte transmembrane adaptor 1 "K05850|1|3e-08|41.6|ocu:103351001|Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0019904//protein domain specific binding;GO:0019900//kinase binding;GO:0019904//protein domain specific binding;GO:0019900//kinase binding GO:0043407//negative regulation of MAP kinase activity;GO:0002377//immunoglobulin production;GO:0042110//T cell activation;GO:0002429//immune response-activating cell surface receptor signaling pathway;GO:0043407//negative regulation of MAP kinase activity;GO:0002377//immunoglobulin production;GO:0042110//T cell activation;GO:0002429//immune response-activating cell surface receptor signaling pathway "gi|148707691|gb|EDL39638.1|/0/lymphocyte transmembrane adaptor 1, isoform CRA_b, partial [Mus musculus]" 14724 1847 0.213333333 0.18 -0.245112498 Down 0.115094588 Gp1bb "glycoprotein Ib, beta polypeptide" K06262|1|1e-64|250|mmu:14724|platelet glycoprotein Ib beta chain GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0005488//binding;GO:0005488//binding GO:0022610;GO:0001775//cell activation;GO:0072376//protein activation cascade;GO:0007599//hemostasis;GO:0022610;GO:0001775//cell activation;GO:0072376//protein activation cascade;GO:0007599//hemostasis gi|826323860|ref|XP_012510403.1|/3.01291e-69/PREDICTED: LOW QUALITY PROTEIN: platelet glycoprotein Ib beta chain [Propithecus coquereli] 74487 1509 1.206666667 1.15 -0.069393335 Down 0.115019369 5430405H02Rik RIKEN cDNA 5430405H02 gene K19553|1|5e-34|148|mmu:228839|homeobox protein TGIF2 - - - - 100503044 1654.98 1.156666667 1.1 -0.072469638 Down 0.115019369 A730020M07Rik RIKEN cDNA A730020M07 gene - - - - - 329506 6737 1.253333333 1.193333333 -0.070773074 Down 0.115019369 Ctdspl2 "CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2" K17616|1|0.0|901|mmu:329506|CTD small phosphatase-like protein 2 [EC:3.1.3.-] - GO:0016791//phosphatase activity;GO:0016791//phosphatase activity;GO:0016791//phosphatase activity GO:0006796//phosphate-containing compound metabolic process "gi|148696132|gb|EDL28079.1|/0/CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2, isoform CRA_a, partial [Mus musculus]" 101831 1788 1.14 1.2 0.074000581 Up 0.115019369 Faap24 Fanconi anemia core complex associated protein 24 K10898|1|7e-120|433|mmu:101831|fanconi anemia-associated protein GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress gi|30519993|ref|NP_848758.1|/5.81628e-119/Fanconi anemia core complex-associated protein 24 [Mus musculus] 67120 9572 1.096666667 1.153333333 0.072684454 Up 0.115019369 Ttc14 tetratricopeptide repeat domain 14 K13619|1|2e-22|112|aqu:105315597|phospholipase DDHD1 [EC:3.1.1.-] - GO:0005488//binding;GO:0003676//nucleic acid binding;GO:0005488//binding;GO:0003676//nucleic acid binding - gi|26334203|dbj|BAC30819.1|/0/unnamed protein product [Mus musculus] 18551 2514 1.173333333 1.23 0.068045387 Up 0.115019369 Pcsk4 proprotein convertase subtilisin/kexin type 4 K08671|1|0.0|1234|mmu:18551|proprotein convertase subtilisin/kexin type 4 [EC:3.4.21.-] - - - gi|33469095|ref|NP_032819.1|/0/proprotein convertase subtilisin/kexin type 4 precursor [Mus musculus] 71481 4795 0.386666667 0.35 -0.143735477 Down 0.115009967 Alpk1 alpha-kinase 1 K08868|1|0.0|2288|mmu:71481|alpha-kinase - - - gi|254553408|ref|NP_082084.1|/0/alpha-protein kinase 1 [Mus musculus] 68616 1081 0.42 0.463333333 0.141661149 Up 0.115009967 Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 K04371|1|7e-46|186|asn:102375250|mitogen-activated protein kinase 1/3 [EC:2.7.11.24];K19179|2|3e-11|72.0|cel:CELE_T12B3.3|glycerophosphoinositol glycerophosphodiesterase [EC:3.1.4.44] GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0008081//phosphoric diester hydrolase activity GO:0019400 gi|110431346|ref|NP_077190.2|/2.30358e-177/glycerophosphodiester phosphodiesterase domain-containing protein 3 [Mus musculus] 241226 5782 0.433333333 0.393333333 -0.139724764 Down 0.115009967 Itga8 integrin alpha 8 K06584|1|0.0|2086|mmu:241226|integrin alpha 8 GO:0044327//dendritic spine head;GO:0032589//neuron projection membrane;GO:0008305//integrin complex;GO:0043025//neuronal cell body GO:0043169//cation binding GO:0007417//central nervous system development;GO:0007611//learning or memory;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001822//kidney development;GO:0060537//muscle tissue development;GO:0008104//protein localization;GO:0031589//cell-substrate adhesion;GO:0048869//cellular developmental process;GO:0042471//ear morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043062//extracellular structure organization gi|47717127|ref|NP_001001309.1|/0/integrin alpha-8 precursor [Mus musculus] 20196 732 28.25666667 27.96 -0.015226926 Down 0.114859528 S100a13 S100 calcium binding protein A13 - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0044421 GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0019838//growth factor binding GO:0002279;GO:0022604//regulation of cell morphogenesis;GO:0045184//establishment of protein localization;GO:0032610//interleukin-1 alpha production;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0008283//cell proliferation gi|347582617|ref|NP_033139.2|/1.17528e-73/protein S100-A13 [Mus musculus] 52432 2079 26.51 26.81 0.016234549 Up 0.114859528 Ppp2r2d "protein phosphatase 2, regulatory subunit B, delta" K04354|1|0.0|872|mmu:52432|serine/threonine-protein phosphatase 2A regulatory subunit B GO:0008287//protein serine/threonine phosphatase complex;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen GO:0016791//phosphatase activity;GO:0019888//protein phosphatase regulator activity GO:0007154//cell communication;GO:0000087//mitotic M phase gi|22726177|ref|NP_080667.1|/0/serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform [Mus musculus] 381760 1201.21 18.43666667 18.13333333 -0.023933691 Down 0.114859528 Ssbp1 single-stranded DNA binding protein 1 K03111|1|2e-76|289|cge:100772064|single-strand DNA-binding protein GO:0032991//macromolecular complex;GO:0005759//mitochondrial matrix;GO:0005759//mitochondrial matrix;GO:0032991//macromolecular complex;GO:0005759//mitochondrial matrix;GO:0032991//macromolecular complex;GO:0005759//mitochondrial matrix GO:0036094//small molecule binding;GO:0043566//structure-specific DNA binding;GO:0043566//structure-specific DNA binding;GO:0036094//small molecule binding;GO:0043566//structure-specific DNA binding;GO:0036094//small molecule binding;GO:0043566//structure-specific DNA binding GO:0051095;GO:0006259//DNA metabolic process;GO:0007005//mitochondrion organization;GO:0010467//gene expression;GO:0051095;GO:0006259//DNA metabolic process;GO:0007005//mitochondrion organization;GO:0051095;GO:0006259//DNA metabolic process;GO:0007005//mitochondrion organization;GO:0010467//gene expression;GO:0051095;GO:0006259//DNA metabolic process;GO:0007005//mitochondrion organization;GO:0010467//gene expression "gi|47058964|ref|NP_082634.1|/4.34346e-80/single-stranded DNA-binding protein, mitochondrial isoform 2 [Mus musculus]" 13204 3058.14 20.96 20.66 -0.020798463 Down 0.114859528 Dhx15 DEAH (Asp-Glu-Ala-His) box polypeptide 15 K12820|1|0.0|963|ggo:101141726|pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15/PRP43 [EC:3.6.4.13] - - - - 16993 2059.54 17.49333333 17.79333333 0.024531586 Up 0.114859528 Lta4h leukotriene A4 hydrolase K01254|1|0.0|928|pon:100171657|leukotriene-A4 hydrolase [EC:3.3.2.6] GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0016803 GO:0006518//peptide metabolic process;GO:0010038//response to metal ion;GO:0009725//response to hormone;GO:0060487//lung epithelial cell differentiation;GO:0006690//icosanoid metabolic process;GO:0019538//protein metabolic process;GO:0006636//unsaturated fatty acid biosynthetic process gi|116734870|ref|NP_032543.2|/0/leukotriene A-4 hydrolase isoform 1 [Mus musculus] 15485 1317 0.186666667 0.22 0.237039197 Up 0.114850126 Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 K00044|1|0.0|682|mmu:15485|17beta-estradiol 17-dehydrogenase [EC:1.1.1.62] GO:0044444//cytoplasmic part "GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0036094//small molecule binding" GO:0010038//response to metal ion;GO:0001501//skeletal system development;GO:0006702//androgen biosynthetic process gi|6754248|ref|NP_034605.1|/0/estradiol 17-beta-dehydrogenase 1 [Mus musculus] 259302 8887 0.173333333 0.146666667 -0.2410081 Down 0.114850126 Srgap3 SLIT-ROBO Rho GTPase activating protein 3 K07526|1|0.0|2008|mmu:259302|SLIT-ROBO Rho GTPase activating protein GO:0044444//cytoplasmic part GO:0008047//enzyme activator activity;GO:0005488//binding GO:0007264//small GTPase mediated signal transduction gi|154090967|ref|NP_536696.4|/0/SLIT-ROBO Rho GTPase-activating protein 3 [Mus musculus] 240869 3883 0.186666667 0.22 0.237039197 Up 0.114850126 Zbtb37 zinc finger and BTB domain containing 37 K10509|1|0.0|1021|mmu:240869|zinc finger and BTB domain-containing protein 37 GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding - gi|27734134|ref|NP_775600.1|/0/zinc finger and BTB domain-containing protein 37 [Mus musculus] 53972 2764 0.193333333 0.163333333 -0.243271151 Down 0.114850126 Ngef neuronal guanine nucleotide exchange factor K07525|1|0.0|1127|mmu:53972|neuronal guanine nucleotide exchange factor GO:0043005//neuron projection;GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0044424 GO:0005102//receptor binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0005102//receptor binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding GO:0048731//system development;GO:0007266//Rho protein signal transduction;GO:0012501//programmed cell death;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048869//cellular developmental process;GO:0031345//negative regulation of cell projection organization;GO:0048731//system development;GO:0007266//Rho protein signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048869//cellular developmental process;GO:0031345//negative regulation of cell projection organization gi|162417959|ref|NP_063920.2|/0/ephexin-1 isoform 2 [Mus musculus] 109254 2440 0.75 0.796666667 0.087085617 Up 0.114624469 Adtrp androgen dependent TFPI regulating protein - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|568982317|ref|XP_006516898.1|/1.14892e-150/PREDICTED: androgen-dependent TFPI-regulating protein isoform X1 [Mus musculus] 319262 4227 0.73 0.776666667 0.089399085 Up 0.114624469 Fchsd1 FCH and double SH3 domains 1 K20125|1|0.0|1128|mmu:319262|F-BAR and double SH3 domains protein - - - - 54631 5661 0.746666667 0.7 -0.093109404 Down 0.114624469 Nphs1 "nephrosis 1, nephrin" K11394|1|0.0|717|ssc:100524089|hydroxyproline oxidase [EC:1.5.-.-];K17341|4|3e-38|164|rno:686132|hemicentin GO:0032991//macromolecular complex;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0036056 GO:0042805//actinin binding GO:0007588//excretion;GO:0030198//extracellular matrix organization;GO:0014706//striated muscle tissue development;GO:0030041//actin filament polymerization;GO:0000768//syncytium formation by plasma membrane fusion;GO:0022610;GO:0097205//renal filtration;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0051403//stress-activated MAPK cascade gi|120586997|ref|NP_062332.2|/0/nephrin precursor [Mus musculus] 246727 4718 0.82 0.87 0.085391491 Up 0.114624469 Oas3 2'-5' oligoadenylate synthetase 3 K14216|1|0.0|2284|mmu:246727|2'-5'-oligoadenylate synthetase [EC:2.7.7.84] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0032550;GO:0003723//RNA binding;GO:0070566//adenylyltransferase activity GO:0019079//viral genome replication;GO:0006952//defense response;GO:0051707//response to other organism;GO:0032069;GO:0019221//cytokine-mediated signaling pathway;GO:0002252 gi|21644585|ref|NP_660261.1|/0/2'-5'-oligoadenylate synthase 3 [Mus musculus] 70676 2976 0.806666667 0.86 0.092364018 Up 0.114624469 Gulp1 "GULP, engulfment adaptor PTB domain containing 1" K11322|1|2e-44|183|api:100158774|enhancer of polycomb-like protein;K12474|2|2e-17|94.0|mdo:100014014|low density lipoprotein receptor adapter protein 1 GO:0044424 - GO:0012501//programmed cell death;GO:0006909//phagocytosis;GO:0010876//lipid localization gi|164518895|ref|NP_082726.2|/1.06367e-174/PTB domain-containing engulfment adapter protein 1 [Mus musculus] 320997 2618 0.026666667 0.01 -1.415037499 Down 0.114605664 Cyp4f39 "cytochrome P450, family 4, subfamily f, polypeptide 39" "K00490|1|0.0|1044|mmu:320997|cytochrome P450, family 4, subfamily F [EC:1.14.14.1];K17731|2|0.0|998|cge:100772743|cytochrome P450, family 4, subfamily F, polypeptide 22" - GO:0046914//transition metal ion binding;GO:0016491//oxidoreductase activity;GO:0046906//tetrapyrrole binding GO:0044710 "gi|28893407|ref|NP_796281.1|/0/cytochrome P450, family 2, subfamily E, polypeptide 2 homolog [Mus musculus]" 11595 7355 0.036666667 0.016666667 -1.137503524 Down 0.114605664 Acan aggrecan K06792|1|0.0|3856|mmu:11595|aggrecan 1 GO:0005578//proteinaceous extracellular matrix;GO:0044420//extracellular matrix component GO:0046872//metal ion binding;GO:0005198//structural molecule activity GO:0006029//proteoglycan metabolic process;GO:0016477//cell migration;GO:0007417//central nervous system development;GO:0009746;GO:0002062//chondrocyte differentiation;GO:0070848//response to growth factor;GO:0009268//response to pH;GO:0030198//extracellular matrix organization;GO:0009605//response to external stimulus gi|116875858|ref|NP_031450.2|/0/aggrecan core protein precursor [Mus musculus] 12821 5428 0.04 0.016666667 -1.263034406 Down 0.114605664 Col17a1 "collagen, type XVII, alpha 1" "K07603|1|0.0|1462|mmu:12821|collagen, type XVII, alpha" GO:0030055//cell-substrate junction;GO:0005576//extracellular region;GO:0030055//cell-substrate junction;GO:0005576//extracellular region - - gi|226423931|ref|NP_031758.2|/0/collagen alpha-1(XVII) chain isoform 2 [Mus musculus] 77631 2540 0.01 0.026666667 1.415037499 Up 0.114605664 4930554H23Rik RIKEN cDNA 4930554H23 gene - - - - - 328795 2953 0.023333333 0.046666667 1 Up 0.114605664 Ubash3a "ubiquitin associated and SH3 domain containing, A" K18993|1|0.0|1206|mmu:328795|ubiquitin-associated and SH3 domain-containing protein [EC:3.1.3.48] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - GO:0050852//T cell receptor signaling pathway gi|165905557|ref|NP_808491.2|/0/ubiquitin-associated and SH3 domain-containing protein A [Mus musculus] 19771 2138 0.01 0.026666667 1.415037499 Up 0.114605664 Rlbp1 retinaldehyde binding protein 1 K19625|1|6e-163|577|mmu:19771|retinaldehyde-binding protein 1 GO:0044424;GO:0044424 GO:0016918//retinal binding;GO:0016918//retinal binding GO:0051234//establishment of localization;GO:0050953//sensory perception of light stimulus;GO:0051234//establishment of localization;GO:0050953//sensory perception of light stimulus gi|10181110|ref|NP_065624.1|/5.51783e-162/retinaldehyde-binding protein 1 [Mus musculus] 209590 2488 0.01 0.026666667 1.415037499 Up 0.114605664 Il23r interleukin 23 receptor K05065|1|0.0|1354|mmu:209590|interleukin 23 receptor GO:0005887//integral component of plasma membrane GO:0005126//cytokine receptor binding;GO:0004896//cytokine receptor activity;GO:0019955//cytokine binding GO:0050691//regulation of defense response to virus by host;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0019221//cytokine-mediated signaling pathway;GO:0042742//defense response to bacterium;GO:0046635//positive regulation of alpha-beta T cell activation;GO:0001819//positive regulation of cytokine production;GO:0042504;GO:0001787//natural killer cell proliferation;GO:0002237//response to molecule of bacterial origin;GO:0010534//regulation of activation of JAK2 kinase activity;GO:0010455//positive regulation of cell fate commitment;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0002824;GO:0001818//negative regulation of cytokine production;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0042102//positive regulation of T cell proliferation gi|239052137|ref|NP_653131.2|/0/interleukin-23 receptor [Mus musculus] 70859 2519 0.01 0.026666667 1.415037499 Up 0.114605664 Lrrc63 leucine rich repeat containing 63 K19613|1|2e-14|84.3|spu:593857|leucine-rich repeat protein SHOC2;K16175|4|8e-13|78.6|hro:HELRODRAFT_192304|protein scribble - - - gi|267844854|ref|NP_081857.1|/0/leucine-rich repeat-containing protein 63 [Mus musculus] 20675 2086 0.01 0.026666667 1.415037499 Up 0.114605664 Sox3 SRY (sex determining region Y)-box 3 K09267|1|1e-121|439|mmu:20675|transcription factor SOX1/3/14/21 (SOX group B) - - GO:0044767//single-organism developmental process;GO:0007399//nervous system development;GO:0048513//animal organ development;GO:0003006//developmental process involved in reproduction gi|156766077|ref|NP_033263.2|/9.88643e-121/transcription factor SOX-3 [Mus musculus] 226245 2385 0.046666667 0.023333333 -1 Down 0.114605664 Plekhs1 "pleckstrin homology domain containing, family S member 1" K04397|1|1e-31|141|cmy:102934687|caspase 7 [EC:3.4.22.60];K20231|2|2e-06|57.0|dwi:Dwil_GK12654|protein daughter of sevenless - - - "gi|148669812|gb|EDL01759.1|/0/RIKEN cDNA 9930023K05, isoform CRA_c, partial [Mus musculus]" 26927 2520 0.01 0.026666667 1.415037499 Up 0.114605664 Foxl2 forkhead box L2 K09405|1|2e-108|396|mmu:26927|forkhead box protein L - - - gi|22779928|ref|NP_036150.1|/1.57321e-107/forkhead box protein L2 [Mus musculus] 26358 2060 0.026666667 0.01 -1.415037499 Down 0.114605664 Aldh1a7 "aldehyde dehydrogenase family 1, subfamily A7" K07249|1|0.0|983|mmu:26358|retinal dehydrogenase [EC:1.2.1.36] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0004029//aldehyde dehydrogenase (NAD) activity GO:0048562//embryonic organ morphogenesis;GO:0007612//learning;GO:0043627//response to estrogen;GO:0022602//ovulation cycle process;GO:0006915//apoptotic process;GO:0002138//retinoic acid biosynthetic process;GO:0048565//digestive tract development;GO:0097305//response to alcohol;GO:0016331//morphogenesis of embryonic epithelium;GO:0006950//response to stress;GO:0051260//protein homooligomerization;GO:0006067//ethanol metabolic process "gi|7106242|ref|NP_036051.1|/0/aldehyde dehydrogenase, cytosolic 1 [Mus musculus]" 330737 2553 0.026666667 0.01 -1.415037499 Down 0.114605664 5430403N17Rik RIKEN cDNA 5430403N17 gene - - - - - 233424 4316 0.04 0.016666667 -1.263034406 Down 0.114605664 Tmc3 transmembrane channel-like gene family 3 K10877|1|1e-42|178|tsp:Tsp_10860|DNA repair and recombination protein RAD54B [EC:3.6.4.-] GO:0031224//intrinsic component of membrane - - gi|110665719|ref|NP_808363.3|/0/transmembrane channel-like protein 3 [Mus musculus] 331480 2177 0.01 0.026666667 1.415037499 Up 0.114605664 Gm5126 predicted pseudogene 5126 - - - - gi|686766615|ref|XP_002831839.3|/1.69596e-26/PREDICTED: uncharacterized protein LOC100462467 [Pongo abelii] 791381 1935 0.01 0.026666667 1.415037499 Up 0.114605664 Gm15413 predicted gene 15413 - - - - gi|26346178|dbj|BAC36740.1|/5.90472e-64/unnamed protein product [Mus musculus] 100048658 2209 0.01 0.026666667 1.415037499 Up 0.114605664 Ddx43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 K17043|1|0.0|1181|mmu:100048658|ATP-dependent RNA helicase DDX43 [EC:3.6.4.13] - - - gi|300795358|ref|NP_001177973.1|/0/probable ATP-dependent RNA helicase DDX43 [Mus musculus] 74561 2236 0.01 0.026666667 1.415037499 Up 0.114605664 Nkx6-3 NK6 homeobox 3 K09351|1|3e-152|541|mmu:74561|homeobox protein Nkx-6.3 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated" gi|198278517|ref|NP_083278.1|/2.61755e-151/homeobox protein Nkx-6.3 [Mus musculus] 12173 4663 0.01 0.026666667 1.415037499 Up 0.114605664 Bnc1 basonuclin 1 - GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0009888//tissue development;GO:0006996//organelle organization;GO:0009611//response to wounding;GO:0006360//transcription from RNA polymerase I promoter;GO:0008284//positive regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter gi|148762976|ref|NP_031588.2|/0/zinc finger protein basonuclin-1 [Mus musculus] 330355 12652 0.04 0.016666667 -1.263034406 Down 0.114605664 Dnah6 "dynein, axonemal, heavy chain 6" "K10408|1|0.0|8036|mmu:330355|dynein heavy chain, axonemal" - - - "gi|257467659|ref|NP_001158141.1|/0/dynein heavy chain 6, axonemal [Mus musculus]" 17882 6083 0.026666667 0.01 -1.415037499 Down 0.114605664 Myh2 "myosin, heavy polypeptide 2, skeletal muscle, adult" K10352|1|0.0|3358|mmu:17882|myosin heavy chain GO:0031981//nuclear lumen;GO:0005924//cell-substrate adherens junction;GO:0016460//myosin II complex;GO:0030017//sarcomere GO:0008092//cytoskeletal protein binding;GO:0032550 GO:0050896//response to stimulus;GO:0031033//myosin filament organization;GO:0007009//plasma membrane organization;GO:0003012//muscle system process gi|205830428|ref|NP_001034634.2|/0/myosin-2 [Mus musculus] 329972 2513 0.01 0.026666667 1.415037499 Up 0.114605664 Spata21 spermatogenesis associated 21 K18626|1|6e-06|55.8|cmk:103191497|trichohyalin - GO:0046872//metal ion binding - gi|29244468|ref|NP_808535.1|/0/spermatogenesis-associated protein 21 [Mus musculus] 319888 3431 0.02 0.043333333 1.115477217 Up 0.114605664 Oacyl O-acyltransferase like - - - - gi|28892903|ref|NP_796002.1|/0/O-acyltransferase like precursor [Mus musculus] 12622 1742 0.016666667 0.04 1.263034406 Up 0.114605664 Cer1 "cerberus 1, DAN family BMP antagonist" K01645|1|1e-152|542|mmu:12622|cerberus 1 - - - - 381204 2238 0.026666667 0.01 -1.415037499 Down 0.114605664 Naaladl1 N-acetylated alpha-linked acidic dipeptidase-like 1 K01301|1|0.0|1360|mmu:381204|N-acetylated-alpha-linked acidic dipeptidase [EC:3.4.17.21] GO:0044459;GO:0031224//intrinsic component of membrane GO:0008238//exopeptidase activity;GO:0043169//cation binding GO:0019538//protein metabolic process gi|57222282|ref|NP_001009546.1|/0/N-acetylated-alpha-linked acidic dipeptidase-like protein [Mus musculus] 21667 1948 0.01 0.026666667 1.415037499 Up 0.114605664 Tdgf1 teratocarcinoma-derived growth factor 1 - GO:0031224//intrinsic component of membrane;GO:0019898//extrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044444//cytoplasmic part;GO:0044421 GO:0070697//activin receptor binding;GO:0038023//signaling receptor activity GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001952//regulation of cell-matrix adhesion;GO:0070741//response to interleukin-6;GO:0006915//apoptotic process;GO:0016055//Wnt signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0048732//gland development;GO:0043009//chordate embryonic development;GO:0032924//activin receptor signaling pathway;GO:0034341//response to interferon-gamma;GO:0035051//cardiocyte differentiation;GO:0001934//positive regulation of protein phosphorylation;GO:0035728//response to hepatocyte growth factor;GO:0070849//response to epidermal growth factor;GO:0010594//regulation of endothelial cell migration;GO:0000578//embryonic axis specification;GO:0006366//transcription from RNA polymerase II promoter;GO:0038127//ERBB signaling pathway;GO:0002040//sprouting angiogenesis;GO:0048598//embryonic morphogenesis;GO:0034612//response to tumor necrosis factor gi|134053945|ref|NP_035692.2|/1.36231e-92/teratocarcinoma-derived growth factor precursor [Mus musculus] 381246 1926 0.01 0.026666667 1.415037499 Up 0.114605664 Xkr9 X-linked Kx blood group related 9 K01128|1|6e-19|98.6|clv:102091645|sphingomyelin phosphodiesterase acid-like 3 [EC:3.1.4.-] - - - - 73895 2282 0.01 0.026666667 1.415037499 Up 0.114605664 4930431P03Rik RIKEN cDNA 4930431P03 gene - - - - - 20674 2480 0.026666667 0.01 -1.415037499 Down 0.114605664 Sox2 SRY (sex determining region Y)-box 2 K16796|1|3e-153|491|ggo:101130724|transcription factor SOX2 (SOX group B) GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0044212//transcription regulatory region DNA binding;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding" GO:0006915//apoptotic process;GO:0048754//branching morphogenesis of an epithelial tube;GO:0046546//development of primary male sexual characteristics;GO:0007405//neuroblast proliferation;GO:0050954//sensory perception of mechanical stimulus;GO:0021543//pallium development;GO:0001708//cell fate specification;GO:0022402//cell cycle process;GO:0042471//ear morphogenesis;GO:0050957//equilibrioception;GO:0002089//lens morphogenesis in camera-type eye;GO:0033993//response to lipid;GO:0001649//osteoblast differentiation;GO:0007219//Notch signaling pathway;GO:0021872//forebrain generation of neurons;GO:0010001//glial cell differentiation;GO:0030182//neuron differentiation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0021983//pituitary gland development;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030855//epithelial cell differentiation;GO:0043584//nose development;GO:0006950//response to stress;GO:0051276//chromosome organization;GO:0000165//MAPK cascade;GO:0019827//stem cell population maintenance;GO:0030324//lung development gi|426343024|ref|XP_004038119.1|/2.78618e-152/PREDICTED: transcription factor SOX-2 [Gorilla gorilla gorilla] 19668 2456 0.026666667 0.01 -1.415037499 Down 0.114605664 Rbpjl recombination signal binding protein for immunoglobulin kappa J region-like K06053|1|0.0|1041|mmu:19668|recombining binding protein suppressor of hairless GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0003676//nucleic acid binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding" GO:0006366//transcription from RNA polymerase II promoter gi|6677689|ref|NP_033062.1|/0/recombining binding protein suppressor of hairless-like protein [Mus musculus] 227717 2925 0.023333333 0.046666667 1 Up 0.114605664 Qrfp pyroglutamylated RFamide peptide - - - - - 63859 3587 0.016666667 0.04 1.263034406 Up 0.114605664 Impg1 interphotoreceptor matrix proteoglycan 1 K19016|1|0.0|1506|mmu:63859|interphotoreceptor matrix proteoglycan 1 GO:0031012//extracellular matrix GO:0005198//structural molecule activity GO:0050953//sensory perception of light stimulus "gi|148694492|gb|EDL26439.1|/0/interphotoreceptor matrix proteoglycan 1, isoform CRA_c, partial [Mus musculus]" 12788 2750 0.026666667 0.01 -1.415037499 Down 0.114605664 Cnga1 cyclic nucleotide gated channel alpha 1 K04948|1|0.0|1218|mmu:12788|cyclic nucleotide gated channel alpha 1 GO:0001750//photoreceptor outer segment;GO:0033267;GO:0034703//cation channel complex GO:0030551//cyclic nucleotide binding;GO:0005221//intracellular cyclic nucleotide activated cation channel activity GO:0050953//sensory perception of light stimulus;GO:0006874//cellular calcium ion homeostasis;GO:0044765//single-organism transport;GO:0048232//male gamete generation;GO:0042391//regulation of membrane potential gi|568933714|ref|XP_006503772.1|/0/PREDICTED: cGMP-gated cation channel alpha-1 isoform X1 [Mus musculus] 227326 2550 0.026666667 0.01 -1.415037499 Down 0.114605664 Gpr55 G protein-coupled receptor 55 K08413|1|0.0|645|mmu:227326|G protein-coupled receptor 55 - - - gi|755494164|ref|XP_011246287.1|/0/PREDICTED: G-protein coupled receptor 55 isoform X2 [Mus musculus] 246048 2530 0.026666667 0.01 -1.415037499 Down 0.114605664 Chodl chondrolectin K10078|1|5e-137|491|mmu:246048|chondrolectin GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane GO:0005539//glycosaminoglycan binding GO:0048513//animal organ development "gi|148665884|gb|EDK98300.1|/8.00278e-152/chondrolectin, isoform CRA_b, partial [Mus musculus]" 77055 2312 0.01 0.026666667 1.415037499 Up 0.114605664 Krt76 keratin 76 "K07605|1|0.0|677|mmu:77055|type II keratin, basic" GO:0005882//intermediate filament - GO:0044763 "gi|148672072|gb|EDL04019.1|/0/mCG144546, partial [Mus musculus]" 244595 1980 0.01 0.026666667 1.415037499 Up 0.114605664 Ces1a carboxylesterase 1A K01044|1|0.0|863|ocu:100009551|carboxylesterase 1 [EC:3.1.1.1] - - - gi|283135142|ref|NP_001013786.2|/0/carboxylesterase 1-like precursor [Mus musculus] 107065 5673 0.016666667 0.04 1.263034406 Up 0.114605664 Lrrtm2 leucine rich repeat transmembrane neuronal 2 K16665|1|0.0|1032|mmu:107065|leucine-rich repeat transmembrane neuronal protein 1/2 - - - - 16392 2526 0.026666667 0.01 -1.415037499 Down 0.114605664 Isl1 "ISL1 transcription factor, LIM/homeodomain" K09370|1|0.0|725|pale:102896694|insulin gene enhancer protein ISL-1 GO:0043231//intracellular membrane-bounded organelle GO:0035258//steroid hormone receptor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0046914//transition metal ion binding;GO:0000976//transcription regulatory region sequence-specific DNA binding GO:0006954//inflammatory response;GO:0021522//spinal cord motor neuron differentiation;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0032610//interleukin-1 alpha production;GO:0001709//cell fate determination;GO:0007411//axon guidance;GO:0032611//interleukin-1 beta production;GO:0043009//chordate embryonic development;GO:0032091//negative regulation of protein binding;GO:0051384//response to glucocorticoid;GO:0001708//cell fate specification;GO:0001667//ameboidal-type cell migration;GO:0003128//heart field specification;GO:0010002//cardioblast differentiation;GO:0021536//diencephalon development;GO:0021545//cranial nerve development;GO:0003151//outflow tract morphogenesis;GO:0001819//positive regulation of cytokine production;GO:0030178//negative regulation of Wnt signaling pathway;GO:0003209//cardiac atrium morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0051099//positive regulation of binding;GO:0050796//regulation of insulin secretion;GO:0043066//negative regulation of apoptotic process;GO:0003264//regulation of cardioblast proliferation;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0036301;GO:0003208//cardiac ventricle morphogenesis "gi|440908077|gb|ELR58138.1|/0/Insulin enhancer protein ISL-1, partial [Bos mutus]" 244757 3698 0.02 0.04 1 Up 0.114605664 Glb1l2 "galactosidase, beta 1-like 2" K12309|1|3e-108|396|sko:100373531|beta-galactosidase [EC:3.2.1.23] - GO:0015925//galactosidase activity GO:0044238//primary metabolic process gi|895798791|ref|NP_001297697.1|/0/beta-galactosidase-1-like protein 2 isoform 2 precursor [Mus musculus] 15206 2521 0.026666667 0.01 -1.415037499 Down 0.114605664 Hes2 hairy and enhancer of split 2 (Drosophila) K09087|1|3e-61|239|mmu:15206|hairy and enhancer of split 2/6/7 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0043566//structure-specific DNA binding;GO:0005515//protein binding;GO:0043566//structure-specific DNA binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|61098067|ref|NP_032262.2|/1.88441e-60/transcription factor HES-2 [Mus musculus] 330721 2404 0.026666667 0.01 -1.415037499 Down 0.114605664 Nek5 NIMA (never in mitosis gene a)-related expressed kinase 5 K08857|1|0.0|1259|mmu:330721|NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] - - - - 106722 2382 0.01 0.026666667 1.415037499 Up 0.114605664 G6b immunoreceptor tyrosine-based inhibitory motif (ITIM) containing platelet receptor - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005539//glycosaminoglycan binding;GO:0005539//glycosaminoglycan binding - gi|85701726|ref|NP_001028393.1|/2.97112e-94/protein G6b isoform 2 precursor [Mus musculus] 320684 2288 0.026666667 0.01 -1.415037499 Down 0.114605664 9630028H03Rik RIKEN cDNA 9630028H03 gene - - - - - 18459 2586 0.026666667 0.01 -1.415037499 Down 0.114605664 Pabpc2 "poly(A) binding protein, cytoplasmic 2" K13126|1|0.0|1165|mmu:18459|polyadenylate-binding protein - - - - 237310 2468 0.01 0.026666667 1.415037499 Up 0.114605664 Il22ra2 "interleukin 22 receptor, alpha 2" K05139|1|4e-129|464|mmu:237310|interleukin 22 receptor alpha 2 GO:0044444//cytoplasmic part GO:0019955//cytokine binding;GO:0004896//cytokine receptor activity GO:0042503//tyrosine phosphorylation of Stat3 protein "gi|148671504|gb|EDL03451.1|/2.42909e-129/interleukin 22 receptor, alpha 2, partial [Mus musculus]" 244694 2662 0.026666667 0.01 -1.415037499 Down 0.114605664 Kdm4d lysine (K)-specific demethylase 4D K06709|1|0.0|985|mmu:244694|jumonji domain-containing protein 2 [EC:1.14.11.-] - - - - 69761 2493 0.026666667 0.01 -1.415037499 Down 0.114605664 1600015I10Rik RIKEN cDNA 1600015I10 gene K11182|1|0.0|908|ngi:103745358|diamine oxidase [EC:1.4.3.22] - "GO:0048037//cofactor binding;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor" GO:1901564 gi|253735769|ref|NP_001074742.2|/0/diamine oxidase-like protein 1 precursor [Mus musculus] 73940 2055 0.01 0.026666667 1.415037499 Up 0.114605664 Hapln2 hyaluronan and proteoglycan link protein 2 K06851|1|0.0|690|mmu:73940|hyaluronan and proteoglycan link protein 2 GO:0031012//extracellular matrix - GO:0022610 gi|15042971|ref|NP_071314.1|/0/hyaluronan and proteoglycan link protein 2 precursor [Mus musculus] 626596 4008 0.01 0.026666667 1.415037499 Up 0.114605664 Rgs22 regulator of G-protein signalling 22 K16449|1|0.0|1574|ecb:100061011|regulator of G-protein signaling - - GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway gi|307691211|ref|NP_001182677.1|/0/regulator of G-protein signaling 22 [Mus musculus] 21337 2258 0.01 0.026666667 1.415037499 Up 0.114605664 Tacr2 tachykinin receptor 2 K04223|1|0.0|727|mmu:21337|tachykinin receptor 2 GO:0031224//intrinsic component of membrane GO:0004995//tachykinin receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007612//learning;GO:0032275//luteinizing hormone secretion;GO:0045987//positive regulation of smooth muscle contraction;GO:0014821;GO:0030072//peptide hormone secretion;GO:0006811//ion transport;GO:0043114//regulation of vascular permeability;GO:0001956//positive regulation of neurotransmitter secretion gi|258613887|ref|NP_033340.3|/0/substance-K receptor [Mus musculus] 13982 6218 0.03 0.013333333 -1.169925001 Down 0.114605664 Esr1 estrogen receptor 1 (alpha) K08550|1|0.0|1013|mmu:13982|estrogen receptor alpha GO:0033267;GO:0032991//macromolecular complex;GO:0042383//sarcolemma;GO:0005739//mitochondrion;GO:0043025//neuronal cell body;GO:0033267;GO:0032991//macromolecular complex;GO:0042383//sarcolemma;GO:0005739//mitochondrion;GO:0043025//neuronal cell body;GO:0033267;GO:0032991//macromolecular complex;GO:0042383//sarcolemma;GO:0005739//mitochondrion;GO:0043025//neuronal cell body;GO:0033267;GO:0032991//macromolecular complex;GO:0042383//sarcolemma;GO:0005739//mitochondrion;GO:0043025//neuronal cell body;GO:0033267;GO:0032991//macromolecular complex;GO:0042383//sarcolemma;GO:0005739//mitochondrion;GO:0043025//neuronal cell body "GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0008289//lipid binding;GO:0003707//steroid hormone receptor activity;GO:0046914//transition metal ion binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0035256//G-protein coupled glutamate receptor binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0008289//lipid binding;GO:0003707//steroid hormone receptor activity;GO:0046914//transition metal ion binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0035256//G-protein coupled glutamate receptor binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0008289//lipid binding;GO:0003707//steroid hormone receptor activity;GO:0046914//transition metal ion binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0035256//G-protein coupled glutamate receptor binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0008289//lipid binding;GO:0003707//steroid hormone receptor activity;GO:0046914//transition metal ion binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0035256//G-protein coupled glutamate receptor binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0008289//lipid binding;GO:0003707//steroid hormone receptor activity;GO:0046914//transition metal ion binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0035256//G-protein coupled glutamate receptor binding" GO:0008202//steroid metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0001541//ovarian follicle development;GO:0006809//nitric oxide biosynthetic process;GO:0043410//positive regulation of MAPK cascade;GO:0001649//osteoblast differentiation;GO:0040007//growth;GO:0042981//regulation of apoptotic process;GO:0060442//branching involved in prostate gland morphogenesis;GO:0030540//female genitalia development;GO:0030522//intracellular receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0043627//response to estrogen;GO:0044092//negative regulation of molecular function;GO:0060548//negative regulation of cell death;GO:0006366//transcription from RNA polymerase II promoter;GO:0030855//epithelial cell differentiation;GO:0009755//hormone-mediated signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0033598//mammary gland epithelial cell proliferation;GO:0007067//mitotic nuclear division;GO:0032770//positive regulation of monooxygenase activity;GO:0008202//steroid metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0001541//ovarian follicle development;GO:0006809//nitric oxide biosynthetic process;GO:0043410//positive regulation of MAPK cascade;GO:0001649//osteoblast differentiation;GO:0040007//growth;GO:0042981//regulation of apoptotic process;GO:0060442//branching involved in prostate gland morphogenesis;GO:0030540//female genitalia development;GO:0030522//intracellular receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0043627//response to estrogen;GO:0044092//negative regulation of molecular function;GO:0060548//negative regulation of cell death;GO:0006366//transcription from RNA polymerase II promoter;GO:0030855//epithelial cell differentiation;GO:0009755//hormone-mediated signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0033598//mammary gland epithelial cell proliferation;GO:0007067//mitotic nuclear division;GO:0032770//positive regulation of monooxygenase activity;GO:0008202//steroid metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0001541//ovarian follicle development;GO:0006809//nitric oxide biosynthetic process;GO:0043410//positive regulation of MAPK cascade;GO:0001649//osteoblast differentiation;GO:0040007//growth;GO:0042981//regulation of apoptotic process;GO:0060442//branching involved in prostate gland morphogenesis;GO:0030540//female genitalia development;GO:0030522//intracellular receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0043627//response to estrogen;GO:0044092//negative regulation of molecular function;GO:0060548//negative regulation of cell death;GO:0006366//transcription from RNA polymerase II promoter;GO:0030855//epithelial cell differentiation;GO:0009755//hormone-mediated signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0033598//mammary gland epithelial cell proliferation;GO:0007067//mitotic nuclear division;GO:0032770//positive regulation of monooxygenase activity;GO:0008202//steroid metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0001541//ovarian follicle development;GO:0006809//nitric oxide biosynthetic process;GO:0043410//positive regulation of MAPK cascade;GO:0001649//osteoblast differentiation;GO:0040007//growth;GO:0042981//regulation of apoptotic process;GO:0060442//branching involved in prostate gland morphogenesis;GO:0030540//female genitalia development;GO:0030522//intracellular receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0043627//response to estrogen;GO:0044092//negative regulation of molecular function;GO:0060548//negative regulation of cell death;GO:0006366//transcription from RNA polymerase II promoter;GO:0030855//epithelial cell differentiation;GO:0009755//hormone-mediated signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0033598//mammary gland epithelial cell proliferation;GO:0007067//mitotic nuclear division;GO:0032770//positive regulation of monooxygenase activity;GO:0008202//steroid metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0001541//ovarian follicle development;GO:0006809//nitric oxide biosynthetic process;GO:0043410//positive regulation of MAPK cascade;GO:0001649//osteoblast differentiation;GO:0040007//growth;GO:0042981//regulation of apoptotic process;GO:0060442//branching involved in prostate gland morphogenesis;GO:0030540//female genitalia development;GO:0030522//intracellular receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0043627//response to estrogen;GO:0044092//negative regulation of molecular function;GO:0060548//negative regulation of cell death;GO:0006366//transcription from RNA polymerase II promoter;GO:0030855//epithelial cell differentiation;GO:0009755//hormone-mediated signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0033598//mammary gland epithelial cell proliferation;GO:0007067//mitotic nuclear division;GO:0032770//positive regulation of monooxygenase activity gi|700274125|ref|NP_001289462.1|/0/estrogen receptor isoform 2 [Mus musculus] 70129 2345 0.026666667 0.01 -1.415037499 Down 0.114605664 Slc44a4 "solute carrier family 44, member 4" "K15377|1|0.0|1113|mmu:70129|solute carrier family 44 (choline transporter-like protein), member 2/4/5" GO:0031224//intrinsic component of membrane - - gi|12963733|ref|NP_076046.1|/0/choline transporter-like protein 4 [Mus musculus] 14067 7433 0.013333333 0.03 1.169925001 Up 0.114605664 F5 coagulation factor V K03902|1|0.0|4113|mmu:14067|coagulation factor V (labile factor) GO:0031091//platelet alpha granule;GO:0016020//membrane;GO:0044421 GO:0046914//transition metal ion binding GO:0022610;GO:0001775//cell activation;GO:0006887//exocytosis;GO:0007599//hemostasis;GO:0003013//circulatory system process gi|6679731|ref|NP_032002.1|/0/coagulation factor V preproprotein [Mus musculus] 12570 2704 0.026666667 0.01 -1.415037499 Down 0.114605664 Cdk5r2 "cyclin-dependent kinase 5, regulatory subunit 2 (p39)" K19929|1|1e-138|496|mmu:12570|cyclin-dependent kinase 5 activator 2 GO:0044424 GO:0005515//protein binding;GO:0043539//protein serine/threonine kinase activator activity GO:0021586//pons maturation;GO:0017156//calcium ion regulated exocytosis;GO:0021543//pallium development;GO:0051726//regulation of cell cycle;GO:0045860//positive regulation of protein kinase activity;GO:0048646//anatomical structure formation involved in morphogenesis gi|116875854|ref|NP_034002.2|/1.21096e-137/cyclin-dependent kinase 5 activator 2 [Mus musculus] 100504399 3815 0.033333333 0.016666667 -1 Down 0.114605664 C130021I20Rik Riken cDNA C130021I20 gene - - - - - 83398 4333 0.026666667 0.01 -1.415037499 Down 0.114605664 Ndst3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 K02578|1|0.0|988|mmu:83398|heparan sulfate N-deacetylase/N-sulfotransferase NDST3 [EC:3.1.1.- 2.8.2.-] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0034483//heparan sulfate sulfotransferase activity;GO:0016787//hydrolase activity;GO:0034483//heparan sulfate sulfotransferase activity;GO:0016787//hydrolase activity;GO:0034483//heparan sulfate sulfotransferase activity;GO:0016787//hydrolase activity - gi|71043953|ref|NP_112463.2|/0/bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 isoform 1 [Mus musculus] 329872 9307 0.016666667 0.033333333 1 Up 0.114605664 Frem1 Fras1 related extracellular matrix protein 1 K08115|1|2e-62|245|pss:102456884|chondroitin sulfate proteoglycan 4 GO:0031224//intrinsic component of membrane;GO:0005578//proteinaceous extracellular matrix;GO:0031224//intrinsic component of membrane;GO:0005578//proteinaceous extracellular matrix GO:0043169//cation binding;GO:0043169//cation binding GO:0031589//cell-substrate adhesion;GO:0009653//anatomical structure morphogenesis;GO:0031589//cell-substrate adhesion;GO:0009653//anatomical structure morphogenesis gi|52138540|ref|NP_808531.2|/0/FRAS1-related extracellular matrix protein 1 isoform 1 precursor [Mus musculus] 665037 2459 0.026666667 0.01 -1.415037499 Down 0.114605664 Gm7457 predicted gene 7457 - - - - - 319871 2446 0.01 0.026666667 1.415037499 Up 0.114605664 4732490B19Rik RIKEN cDNA 4732490B19 gene - - - - gi|148669137|gb|EDL01138.1|/2.53995e-54/mCG146991 [Mus musculus] 74052 4182 0.02 0.04 1 Up 0.114605664 Ttc21a tetratricopeptide repeat domain 21A K19673|1|0.0|1585|amj:102575395|tetratricopeptide repeat protein 21B - - - gi|225543311|ref|NP_083011.2|/0/tetratricopeptide repeat protein 21A [Mus musculus] 102502 3697 0.01 0.026666667 1.415037499 Up 0.114605664 Pls1 plastin 1 (I-isoform) K17275|1|0.0|1210|mmu:102502|plastin-1 - - - - 54713 2304 0.01 0.026666667 1.415037499 Up 0.114605664 Fezf2 Fez family zinc finger 2 K09228|1|2e-48|196|cjc:100404260|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0007409//axonogenesis;GO:0021766//hippocampus development;GO:0008283//cell proliferation;GO:0021830//interneuron migration from the subpallium to the cortex;GO:0021953//central nervous system neuron differentiation;GO:0006935//chemotaxis;GO:0009952//anterior/posterior pattern specification;GO:0044708//single-organism behavior "gi|148688660|gb|EDL20607.1|/0/zinc finger protein 312, isoform CRA_a, partial [Mus musculus]" 100861755 1196 0.026666667 0.01 -1.415037499 Down 0.114605664 Gm21190 "predicted gene, 21190" - - - - "gi|882939011|ref|NP_001297378.1|/1.77567e-112/predicted gene, 21190 [Mus musculus]" 207911 2205 0.01 0.026666667 1.415037499 Up 0.114605664 Mchr1 melanin-concentrating hormone receptor 1 K04320|1|0.0|663|ocu:100358734|melanin-concentrating hormone receptor 1 - - - gi|34098567|sp|Q8JZL2.2|MCHR1_MOUSE/0/RecName: Full=Melanin-concentrating hormone receptor 1; Short=MCH receptor 1; Short=MCH-R1; Short=MCHR-1; AltName: Full=G-protein coupled receptor 24; AltName: Full=MCH-1R; Short=MCH1R; Short=MCHR; AltName: Full=SLC-1; AltName: Full=Somatostatin receptor-like protein 17433 3286 0.02 0.043333333 1.115477217 Up 0.114605664 Mobp myelin-associated oligodendrocytic basic protein - GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen GO:0005198//structural molecule activity;GO:0005198//structural molecule activity;GO:0005198//structural molecule activity GO:0048731//system development;GO:0048731//system development;GO:0048731//system development "gi|148677232|gb|EDL09179.1|/2.02404e-86/myelin-associated oligodendrocytic basic protein, isoform CRA_c, partial [Mus musculus]" 17954 2606 0.026666667 0.01 -1.415037499 Down 0.114605664 Nap1l2 nucleosome assembly protein 1-like 2 K11280|1|0.0|773|mmu:17954|nucleosome assembly protein 1-like 2 - - GO:0034728//nucleosome organization gi|255958176|ref|NP_032697.2|/0/nucleosome assembly protein 1-like 2 [Mus musculus] 241989 5218 0.016666667 0.04 1.263034406 Up 0.114605664 Pabpc4l "poly(A) binding protein, cytoplasmic 4-like" K13126|1|0.0|729|mmu:241989|polyadenylate-binding protein - GO:0003676//nucleic acid binding - gi|168229272|ref|NP_001094949.1|/0/polyadenylate-binding protein 4-like [Mus musculus] 74855 2833 0.023333333 0.046666667 1 Up 0.114605664 Fam228a "family with sequence similarity 228, member A" - - - - gi|58037391|ref|NP_083383.1|/9.71378e-170/protein FAM228A [Mus musculus] 104940697 2190 0.01 0.026666667 1.415037499 Up 0.114605664 Dalir DNMT1 associated long intergenic non-coding RNA - - - - gi|148690630|gb|EDL22577.1|/3.84799e-06/mCG147769 [Mus musculus] 226356 2511 0.01 0.026666667 1.415037499 Up 0.114605664 Cfap221 cilia and flagella associated protein 221 K17570|1|3e-06|56.6|phu:Phum_PHUM363890|hydrocephalus-inducing protein GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding GO:0048858//cell projection morphogenesis gi|169234918|ref|NP_001108546.1|/0/cilia- and flagella-associated protein 221 [Mus musculus] 383491 2593 0.026666667 0.01 -1.415037499 Down 0.114605664 Prdm14 PR domain containing 14 K12463|1|4e-43|179|sko:102803465|PR domain zinc finger protein 4;K09228|4|6e-41|172|spu:105436471|KRAB domain-containing zinc finger protein - - - gi|163838627|ref|NP_001074678.2|/0/PR domain zinc finger protein 14 [Mus musculus] 50525 2483 0.01 0.026666667 1.415037499 Up 0.114605664 Spag6 sperm associated antigen 6-like K15043|1|2e-17|93.6|nve:NEMVE_v1g195115|importin subunit alpha-2 - - - - 320118 2556 0.01 0.026666667 1.415037499 Up 0.114605664 Fbxl13 F-box and leucine-rich repeat protein 13 K10279|1|0.0|1488|mmu:320118|F-box and leucine-rich repeat protein 13 - - - gi|161333858|ref|NP_796050.2|/0/F-box/LRR-repeat protein 13 isoform b [Mus musculus] 228366 2348 0.026666667 0.01 -1.415037499 Down 0.114605664 Gyltl1b glycosyltransferase-like 1B K09668|1|0.0|1198|mmu:228366|glycosyltransferase-like protein LARGE - - - - 75740 2519 0.026666667 0.01 -1.415037499 Down 0.114605664 Egfem1 EGF-like and EMI domain containing 1 K06825|1|4e-52|209|sko:100374579|fibrillin 1 - - - gi|268370051|ref|NP_083688.1|/0/EGF-like and EMI domain-containing protein 1 isoform a precursor [Mus musculus] 21960 5395 0.04 0.016666667 -1.263034406 Down 0.114605664 Tnr tenascin R K06252|1|0.0|2767|mmu:21960|tenascin GO:0031981//nuclear lumen;GO:0044425;GO:0044420//extracellular matrix component GO:0008289//lipid binding "GO:0007626//locomotory behavior;GO:0007612//learning;GO:0016337//single organismal cell-cell adhesion;GO:0048167//regulation of synaptic plasticity;GO:0007162//negative regulation of cell adhesion;GO:0035249//synaptic transmission, glutamatergic;GO:0010647//positive regulation of cell communication;GO:0030517//negative regulation of axon extension;GO:0043062//extracellular structure organization;GO:0021537//telencephalon development;GO:0050905//neuromuscular process" gi|226958549|ref|NP_071707.2|/0/tenascin-R precursor [Mus musculus] 12728 4170 0.02 0.04 1 Up 0.114605664 Clcn5 "chloride channel, voltage-sensitive 5" K05012|1|0.0|1449|cge:100754025|chloride channel 3/4/5 - - - gi|344313157|ref|NP_001230691.1|/0/H(+)/Cl(-) exchange transporter 5 isoform 2 [Mus musculus] 72780 2411 0.01 0.026666667 1.415037499 Up 0.114605664 Rspo3 R-spondin 3 K19471|1|6e-61|238|lcm:102349873|R-spondin-1 - GO:0001664//G-protein coupled receptor binding;GO:0005539//glycosaminoglycan binding GO:0048598//embryonic morphogenesis;GO:0016055//Wnt signaling pathway gi|269973856|ref|NP_082627.3|/1.53702e-112/R-spondin-3 precursor [Mus musculus] 434065 2304 0.01 0.026666667 1.415037499 Up 0.114605664 Gm1965 predicted gene 1965 - - - - - 442827 4105 0.01 0.026666667 1.415037499 Up 0.114605664 Rab44 "RAB44, member RAS oncogene family" K17199|1|1e-66|258|gga:100859805|Ras and EF-hand domain-containing protein GO:0016020//membrane GO:0032550 GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization gi|569000943|ref|XP_006524656.1|/0/PREDICTED: ras-related protein Rab-44 isoform X3 [Mus musculus] 433486 2672 0.026666667 0.01 -1.415037499 Down 0.114605664 Gm14151 predicted gene 14151 K08798|1|3e-106|389|ngi:103739892|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|148235545|ref|NP_001091446.1|/0/sperm motility kinase X [Mus musculus] 319555 7732 0.02 0.04 1 Up 0.114605664 Nwd1 NACHT and WD repeat domain containing 1 K11127|1|7e-24|117|aqu:100639414|telomerase protein component 1;K11887|2|7e-24|117|ame:409686|proteasomal ATPase-associated factor 1 - - - - 94109 14278 0.036666667 0.016666667 -1.137503524 Down 0.114605664 Csmd1 CUB and Sushi multiple domains 1 K17495|1|0.0|7427|mmu:94109|CUB and sushi domain-containing protein - - - gi|124248566|ref|NP_444401.2|/0/CUB and sushi domain-containing protein 1 precursor [Mus musculus] 64705 2471 0.026666667 0.01 -1.415037499 Down 0.114605664 Dpys dihydropyrimidinase K01464|1|0.0|1058|mmu:64705|dihydropyrimidinase [EC:3.5.2.2] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part "GO:0046914//transition metal ion binding;GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0002061;GO:0031406//carboxylic acid binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0002061;GO:0031406//carboxylic acid binding;GO:0005515//protein binding" GO:0051260//protein homooligomerization;GO:0006520//cellular amino acid metabolic process;GO:0006208//pyrimidine nucleobase catabolic process;GO:0051260//protein homooligomerization;GO:0006520//cellular amino acid metabolic process;GO:0006208//pyrimidine nucleobase catabolic process gi|257095996|ref|NP_073559.3|/0/dihydropyrimidinase [Mus musculus] 435864 2547 0.026666667 0.01 -1.415037499 Down 0.114605664 Vmn2r9 "vomeronasal 2, receptor 9" K04613|1|0.0|1412|mmu:211223|vomeronasal 2 receptor - - - "gi|157277962|ref|NP_001098091.1|/0/vomeronasal 2, receptor 9 precursor [Mus musculus]" 16160 2505 0.026666667 0.01 -1.415037499 Down 0.114605664 Il12b interleukin 12b K05425|1|0.0|678|mmu:16160|interleukin 12B GO:0005615//extracellular space;GO:0044424 GO:0019972//interleukin-12 binding;GO:0005126//cytokine receptor binding;GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0046983//protein dimerization activity GO:0050691//regulation of defense response to virus by host;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0002294;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0048870//cell motility;GO:0001562//response to protozoan;GO:0022402//cell cycle process;GO:0034341//response to interferon-gamma;GO:0002437//inflammatory response to antigenic stimulus;GO:0042742//defense response to bacterium;GO:0002420;GO:0007600//sensory perception;GO:0009411//response to UV;GO:0010661;GO:0046635//positive regulation of alpha-beta T cell activation;GO:0001819//positive regulation of cytokine production;GO:0001866//NK T cell proliferation;GO:0042504;GO:0001787//natural killer cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0007155//cell adhesion;GO:0010534//regulation of activation of JAK2 kinase activity;GO:0044126;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0002824;GO:0001818//negative regulation of cytokine production;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0032496//response to lipopolysaccharide;GO:0042102//positive regulation of T cell proliferation gi|735997434|ref|NP_001290173.1|/0/interleukin-12 subunit beta precursor [Mus musculus] 12733 2405 0.026666667 0.01 -1.415037499 Down 0.114605664 Clcnka "chloride channel, voltage-sensitive Ka" K05017|1|0.0|1256|mmu:12733|chloride channel Ka;K05018|5|0.0|1094|ptg:102964811|chloride channel Kb GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0034702//ion channel complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0034702//ion channel complex GO:0005488//binding;GO:0005254//chloride channel activity;GO:0005488//binding;GO:0005254//chloride channel activity GO:0010038//response to metal ion;GO:0046903//secretion;GO:0009628//response to abiotic stimulus;GO:0015698//inorganic anion transport;GO:0001822//kidney development;GO:0034220//ion transmembrane transport;GO:0006950//response to stress;GO:0010038//response to metal ion;GO:0046903//secretion;GO:0009628//response to abiotic stimulus;GO:0015698//inorganic anion transport;GO:0001822//kidney development;GO:0034220//ion transmembrane transport;GO:0006950//response to stress gi|226423866|ref|NP_077723.3|/0/chloride channel protein ClC-Ka [Mus musculus] 14377 2274 0.026666667 0.01 -1.415037499 Down 0.114605664 G6pc "glucose-6-phosphatase, catalytic" K01084|1|0.0|655|mmu:14377|glucose-6-phosphatase [EC:3.1.3.9] - - - - 74446 2245 0.026666667 0.01 -1.415037499 Down 0.114605664 Slc9b1 "solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1" - GO:0031224//intrinsic component of membrane GO:0015078//hydrogen ion transmembrane transporter activity GO:0006811//ion transport;GO:0044763 gi|167234369|ref|NP_083222.2|/0/sodium/hydrogen exchanger 9B1 [Mus musculus] 280635 3447 0.02 0.04 1 Up 0.114605664 Emilin3 elastin microfibril interfacer 3 K13999|1|2e-07|61.2|tru:101075696|cytoskeleton-associated protein 4;K20478|2|2e-06|57.8|nvi:100121192|golgin subfamily B member 1;K14000|4|7e-06|56.2|bom:102282581|ribosome-binding protein 1;K16469|5|9e-06|55.8|bacu:103011813|rootletin GO:0044424;GO:0031012//extracellular matrix;GO:0044424;GO:0031012//extracellular matrix - - gi|599045616|ref|NP_001278074.1|/0/EMILIN-3 isoform b precursor [Mus musculus] 72040 2143 0.01 0.026666667 1.415037499 Up 0.114605664 Cdhr5 cadherin-related family member 5 K16505|1|0.0|855|mmu:72040|cadherin-related family member 5 GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion;GO:0016337//single organismal cell-cell adhesion gi|167004347|ref|NP_001107794.1|/0/cadherin-related family member 5 isoform 1 precursor [Mus musculus] 100504717 1912 0.01 0.026666667 1.415037499 Up 0.114605664 Gm12709 predicted gene 12709 K20065|1|1e-24|117|shr:100913865|SH3-containing GRB2-like protein 3-interacting protein 1 GO:0030128//clathrin coat of endocytic vesicle GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0015631//tubulin binding GO:0006898//receptor-mediated endocytosis "gi|148698905|gb|EDL30852.1|/9.33943e-38/mCG146032, partial [Mus musculus]" 330921 2215 0.026666667 0.01 -1.415037499 Down 0.114605664 Pate2 prostate and testis expressed 2 - GO:0044421 - - gi|85701929|ref|NP_001028593.1|/1.00835e-62/prostate and testis expressed protein 2 precursor [Mus musculus] 232386 2496 0.026666667 0.01 -1.415037499 Down 0.114605664 Gm38404 "predicted gene, 38404" - - - - - 433944 1352 0.01 0.026666667 1.415037499 Up 0.114605664 Tbx3os2 "T-box 3, opposite strand 2" - - - - - 83560 4776 0.016666667 0.04 1.263034406 Up 0.114605664 Tex14 testis expressed gene 14 K17540|1|0.0|2863|mmu:83560|inactive serine/threonine-protein kinase TEX14 "GO:0000775//chromosome, centromeric region;GO:0044421;GO:0000775//chromosome, centromeric region;GO:0044421" GO:0016301//kinase activity;GO:0032550;GO:0019900//kinase binding;GO:0016301//kinase activity;GO:0032550;GO:0019900//kinase binding GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0043393//regulation of protein binding;GO:0007126//meiotic nuclear division;GO:0000070//mitotic sister chromatid segregation;GO:0006464//cellular protein modification process;GO:0043062//extracellular structure organization;GO:0000910//cytokinesis;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0043393//regulation of protein binding;GO:0007126//meiotic nuclear division;GO:0000070//mitotic sister chromatid segregation;GO:0006464//cellular protein modification process;GO:0043062//extracellular structure organization;GO:0000910//cytokinesis gi|313151212|ref|NP_001186222.1|/0/inactive serine/threonine-protein kinase TEX14 isoform a [Mus musculus] 635702 9713 0.04 0.016666667 -1.263034406 Down 0.114605664 Naaladl2 N-acetylated alpha-linked acidic dipeptidase-like 2 K01301|1|0.0|1412|rno:499583|N-acetylated-alpha-linked acidic dipeptidase [EC:3.4.17.21] - - - - 209195 3743 0.01 0.026666667 1.415037499 Up 0.114605664 Clic6 chloride intracellular channel 6 K05026|1|0.0|883|mmu:209195|chloride intracellular channel protein 6 GO:0016021//integral component of membrane;GO:0044464 GO:0042802//identical protein binding;GO:0050780//dopamine receptor binding;GO:0005254//chloride channel activity GO:0006811//ion transport gi|27369633|ref|NP_766057.1|/0/chloride intracellular channel protein 6 [Mus musculus] 19824 2249 0.026666667 0.01 -1.415037499 Down 0.114605664 Trim10 tripartite motif-containing 10 K12002|1|0.0|956|mmu:19824|tripartite motif-containing protein 10 GO:0044424 GO:0046914//transition metal ion binding GO:0030099//myeloid cell differentiation gi|255069792|ref|NP_035410.2|/0/tripartite motif-containing protein 10 [Mus musculus] 667742 10742 0.01 0.026666667 1.415037499 Up 0.114605664 Piezo2 piezo-type mechanosensitive ion channel component 2 - - - - - 18025 2544 0.026666667 0.01 -1.415037499 Down 0.114605664 Nfe2l3 "nuclear factor, erythroid derived 2, like 3" K09040|1|0.0|1145|mmu:18025|nuclear factor erythroid 2-related factor 1/3 GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated" gi|6754834|ref|NP_035033.1|/0/nuclear factor erythroid 2-related factor 3 [Mus musculus] 13122 4172 0.026666667 0.01 -1.415037499 Down 0.114605664 Cyp7a1 "cytochrome P450, family 7, subfamily a, polypeptide 1" K00489|1|0.0|1023|mmu:13122|cholesterol 7alpha-monooxygenase [EC:1.14.14.23] GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0008395//steroid hydroxylase activity GO:0055092//sterol homeostasis;GO:0006699//bile acid biosynthetic process;GO:0036315//cellular response to sterol;GO:0001678//cellular glucose homeostasis;GO:0008203//cholesterol metabolic process gi|31542445|ref|NP_031850.2|/0/cholesterol 7-alpha-monooxygenase [Mus musculus] 668612 2565 0.026666667 0.01 -1.415037499 Down 0.114605664 Gm9268 predicted gene 9268 K04613|1|0.0|1256|mmu:637873|vomeronasal 2 receptor;K04612|2|0.0|1103|cge:100763896|calcium-sensing receptor - - - gi|157311598|ref|NP_001098531.1|/0/predicted gene 9268 precursor [Mus musculus] 625029 2595 0.01 0.026666667 1.415037499 Up 0.114605664 Vmn2r83 "vomeronasal 2, receptor 83" K04613|1|0.0|1252|mmu:216144|vomeronasal 2 receptor;K04612|2|0.0|942|cge:100763896|calcium-sensing receptor GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway "gi|157151740|ref|NP_001098007.1|/0/vomeronasal 2, receptor 83 precursor [Mus musculus]" 12613 2080 0.01 0.026666667 1.415037499 Up 0.114605664 Cel carboxyl ester lipase K12298|1|0.0|1134|mmu:12613|bile salt-stimulated lipase [EC:3.1.1.3 3.1.1.13] - - - - 16678 2462 0.01 0.026666667 1.415037499 Up 0.114605664 Krt1 keratin 1 "K07605|1|0.0|672|mmu:16678|type II keratin, basic" GO:0005882//intermediate filament;GO:0016020//membrane GO:0005488//binding GO:0006956//complement activation "gi|126116585|ref|NP_032499.2|/0/keratin, type II cytoskeletal 1 [Mus musculus]" 74342 2536 0.01 0.026666667 1.415037499 Up 0.114605664 Lrrtm1 leucine rich repeat transmembrane neuronal 1 K16665|1|0.0|987|mmu:74342|leucine-rich repeat transmembrane neuronal protein 1/2 GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0097060//synaptic membrane - GO:0008104//protein localization;GO:0050896//response to stimulus;GO:0016043//cellular component organization gi|27753993|ref|NP_083156.2|/0/leucine-rich repeat transmembrane neuronal protein 1 precursor [Mus musculus] 66696 2695 0.026666667 0.01 -1.415037499 Down 0.114605664 Snx31 sorting nexin 31 K17937|1|0.0|899|mmu:66696|sorting nexin-31 - GO:0005543//phospholipid binding GO:0045184//establishment of protein localization;GO:0044763 gi|31981209|ref|NP_079988.3|/0/sorting nexin-31 [Mus musculus] 244885 2759 0.023333333 0.046666667 1 Up 0.114605664 Sh2d7 SH2 domain containing 7 K08273|1|7e-06|55.8|chx:102172854|SH2 domain protein 2A - - - "gi|148693868|gb|EDL25815.1|/0/RIKEN cDNA 4933412E14, partial [Mus musculus]" 23925 2524 0.026666667 0.01 -1.415037499 Down 0.114605664 Kel Kell blood group K06577|1|0.0|1381|mmu:23925|Kell blood group glycoprotein [EC:3.4.24.-] - - - - 18071 2506 0.01 0.026666667 1.415037499 Up 0.114605664 Nhlh1 nescient helix loop helix 1 K09075|1|2e-28|130|mmu:18071|nescient helix-loop-helix protein - - GO:0044699;GO:0032502//developmental process gi|6754852|ref|NP_035046.1|/1.59843e-27/helix-loop-helix protein 1 [Mus musculus] 13393 2606 0.01 0.026666667 1.415037499 Up 0.114605664 Dlx3 distal-less homeobox 3 K09315|1|5e-147|524|mmu:13393|homeobox protein DLX3 GO:0043231//intracellular membrane-bounded organelle "GO:0044212//transcription regulatory region DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding" "GO:0042476//odontogenesis;GO:0001944//vasculature development;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated" gi|6753648|ref|NP_034185.1|/3.98592e-146/homeobox protein DLX-3 [Mus musculus] 100042894 2430 0.01 0.026666667 1.415037499 Up 0.114605664 Vmn2r46 "vomeronasal 2, receptor 46" K04613|1|0.0|1584|mmu:76229|vomeronasal 2 receptor GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway "gi|157311643|ref|NP_001098546.1|/0/vomeronasal 2, receptor 46 precursor [Mus musculus]" 628693 898 0.156666667 0.183333333 0.226770862 Up 0.114436421 Gm6904 predicted gene 6904 K18494|1|2e-58|228|mmu:107303348|histone-lysine N-methyltransferase SETDB2 [EC:2.1.1.43];K09186|5|6e-13|77.0|acs:100560745|histone-lysine N-methyltransferase MLL1 [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - gi|256223775|ref|NP_001157801.1|/5.16035e-118/PHD finger protein 11 family member [Mus musculus] 213696 1559 0.223333333 0.19 -0.233199176 Down 0.114436421 Duoxa1 dual oxidase maturation factor 1 K17233|1|1e-175|619|mmu:213696|dual oxidase maturation factor 1 - - - - 78803 4035 0.173333333 0.203333333 0.230297619 Up 0.114436421 Fbxo43 F-box protein 43 K10318|1|0.0|1176|mmu:78803|F-box protein 43 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding GO:0007126//meiotic nuclear division;GO:0032446//protein modification by small protein conjugation;GO:0009895 gi|568990719|ref|XP_006520259.1|/0/PREDICTED: F-box only protein 43 isoform X2 [Mus musculus] 69908 3320 0.18 0.153333333 -0.231325546 Down 0.114436421 Rab3b "RAB3B, member RAS oncogene family" K06108|1|3e-122|442|mmu:69908|Ras-related protein Rab-3B GO:0016020//membrane;GO:0030136//clathrin-coated vesicle GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0006887//exocytosis;GO:0045184//establishment of protein localization;GO:0009154//purine ribonucleotide catabolic process;GO:0006479//protein methylation;GO:0035556//intracellular signal transduction "gi|148698775|gb|EDL30722.1|/9.04992e-122/RAB3B, member RAS oncogene family, isoform CRA_b, partial [Mus musculus]" 270624 4176 0.173333333 0.203333333 0.230297619 Up 0.114436421 Spin4 "spindlin family, member 4" - - - GO:0019953//sexual reproduction gi|30520207|ref|NP_848868.1|/3.50636e-126/spindlin-4 [Mus musculus] 100040322 1898 0.203333333 0.173333333 -0.230297619 Down 0.114436421 3830408C21Rik RIKEN cDNA 3830408C21 gene - - - - - 231842 2685 0.223333333 0.19 -0.233199176 Down 0.114436421 Amz1 archaelysin family metallopeptidase 1 K06974|1|0.0|958|mmu:231842|archaemetzincin [EC:3.4.-.-] - "GO:0043169//cation binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process gi|27734160|ref|NP_775581.1|/0/archaemetzincin-1 [Mus musculus] 208111 5011 0.2 0.17 -0.234465254 Down 0.114436421 9830147E19Rik zinc finger protein 976 K09228|1|0.0|992|cge:103163817|KRAB domain-containing zinc finger protein - - - gi|334724445|ref|NP_001229317.1|/0/zinc finger protein-like [Mus musculus] 50927 2869.09 3.82 3.726666667 -0.035686856 Down 0.1143518 Nasp nuclear autoantigenic sperm protein (histone-binding) K11291|1|4e-148|527|mmu:50927|nuclear autoantigenic sperm protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0031072//heat shock protein binding;GO:0031072//heat shock protein binding;GO:0031072//heat shock protein binding GO:0006259//DNA metabolic process;GO:0045184//establishment of protein localization;GO:0034728//nucleosome organization;GO:0001701//in utero embryonic development;GO:0006259//DNA metabolic process;GO:0051234//establishment of localization;GO:0034728//nucleosome organization;GO:0001701//in utero embryonic development;GO:0006259//DNA metabolic process;GO:0051234//establishment of localization;GO:0034728//nucleosome organization "gi|148698650|gb|EDL30597.1|/0/nuclear autoantigenic sperm protein (histone-binding), isoform CRA_b, partial [Mus musculus]" 319636 6982.13 3.466666667 3.38 -0.036525876 Down 0.1143518 Fsd1l fibronectin type III and SPRY domain containing 1-like K10654|1|2e-07|60.8|pss:102453692|tripartite motif-containing protein 55;K10655|2|6e-07|58.9|cjc:100413206|tripartite motif-containing protein 63 [EC:2.3.2.27] GO:0044464 - - gi|305632826|ref|NP_001182213.1|/0/FSD1-like protein isoform 1 [Mus musculus] 232946 1850 3.776666667 3.87 0.035220111 Up 0.1143518 Bloc1s3 "biogenesis of lysosomal organelles complex-1, subunit 3" K20186|1|1e-44|183|mmu:232946|biogenesis of lysosome-related organelles complex 1 subunit 3 "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0031082" GO:0005488//binding GO:0007423//sensory organ development;GO:0007599//hemostasis;GO:0048753//pigment granule organization;GO:0032401//establishment of melanosome localization;GO:0048489//synaptic vesicle transport;GO:0033363//secretory granule organization;GO:0030030//cell projection organization;GO:0043485//endosome to pigment granule transport;GO:0048193//Golgi vesicle transport;GO:0008088//axo-dendritic transport;GO:0001775//cell activation "gi|148691202|gb|EDL23149.1|/1.86784e-51/biogenesis of lysosome-related organelles complex-1, subunit 3, partial [Mus musculus]" 225160 3855 3.463333333 3.556666667 0.038364522 Up 0.1143518 Thoc1 THO complex 1 K12878|1|0.0|1217|mmu:225160|THO complex subunit 1 GO:0000346//transcription export complex GO:0003676//nucleic acid binding "GO:0006396//RNA processing;GO:0006915//apoptotic process;GO:0006354//DNA-templated transcription, elongation;GO:0006406//mRNA export from nucleus;GO:0007154//cell communication" gi|23956332|ref|NP_705780.1|/0/THO complex subunit 1 [Mus musculus] 328099 4010 3 3.09 0.042644337 Up 0.1143518 Prps1l3 phosphoribosyl pyrophosphate synthetase 1-like 3 K00948|1|6e-178|627|mmu:328099|ribose-phosphate pyrophosphokinase [EC:2.7.6.1] GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0032550;GO:0016778;GO:0046872//metal ion binding;GO:0042802//identical protein binding GO:0006220//pyrimidine nucleotide metabolic process;GO:0009124//nucleoside monophosphate biosynthetic process;GO:0009152//purine ribonucleotide biosynthetic process;GO:0044283//small molecule biosynthetic process;GO:0009887//organ morphogenesis;GO:0009113//purine nucleobase biosynthetic process "gi|440900332|gb|ELR51492.1|/2.44464e-177/Ribose-phosphate pyrophosphokinase 1, partial [Bos mutus]" 13866 4998 3.35 3.263333333 -0.037814736 Down 0.1143518 Erbb2 erb-b2 receptor tyrosine kinase 2 K05083|1|0.0|2392|mmu:13866|receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1] - - - - 319885 2545 3.063333333 3.153333333 0.041775322 Up 0.1143518 Zcchc7 "zinc finger, CCHC domain containing 7" K12597|1|0.0|962|mmu:319885|protein AIR1/2 GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding - gi|169646700|ref|NP_613056.2|/0/zinc finger CCHC domain-containing protein 7 [Mus musculus] 17869 2396 3.453333333 3.366666667 -0.03666871 Down 0.1143518 Myc myelocytomatosis oncogene K04377|1|0.0|650|rno:24577|Myc proto-oncogene protein GO:0044451;GO:0015630//microtubule cytoskeleton;GO:0043005//neuron projection;GO:0032991//macromolecular complex;GO:0044451;GO:0015630//microtubule cytoskeleton;GO:0043005//neuron projection;GO:0032991//macromolecular complex;GO:0044451;GO:0015630//microtubule cytoskeleton;GO:0043005//neuron projection;GO:0032991//macromolecular complex;GO:0044451;GO:0015630//microtubule cytoskeleton;GO:0043005//neuron projection;GO:0032991//macromolecular complex GO:0008134//transcription factor binding;GO:0043566//structure-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0043566//structure-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0043566//structure-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0043566//structure-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding "GO:0000737//DNA catabolic process, endonucleolytic;GO:0000085//mitotic G2 phase;GO:0060070//canonical Wnt signaling pathway;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0009743//response to carbohydrate;GO:0021536//diencephalon development;GO:0006875//cellular metal ion homeostasis;GO:0070555//response to interleukin-1;GO:0045838//positive regulation of membrane potential;GO:0001501//skeletal system development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0007006//mitochondrial membrane organization;GO:0051726//regulation of cell cycle;GO:0001783//B cell apoptotic process;GO:0035879//plasma membrane lactate transport;GO:0010212//response to ionizing radiation;GO:0008637//apoptotic mitochondrial changes;GO:0050877//neurological system process;GO:0008285//negative regulation of cell proliferation;GO:0016568//chromatin modification;GO:0006754//ATP biosynthetic process;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006974//cellular response to DNA damage stimulus;GO:0042471//ear morphogenesis;GO:0031325//positive regulation of cellular metabolic process;GO:0007519//skeletal muscle tissue development;GO:0010829//negative regulation of glucose transport;GO:0043393//regulation of protein binding;GO:0043627//response to estrogen;GO:0009967//positive regulation of signal transduction;GO:0009411//response to UV;GO:0010383;GO:0010243//response to organonitrogen compound;GO:0000723//telomere maintenance;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0019048//modulation by virus of host morphology or physiology;GO:0042493//response to drug;GO:0051604//protein maturation;GO:0006119//oxidative phosphorylation;GO:0044093;GO:0009698//phenylpropanoid metabolic process;GO:0006096//glycolytic process;GO:0000737//DNA catabolic process, endonucleolytic;GO:0000085//mitotic G2 phase;GO:0060070//canonical Wnt signaling pathway;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0009743//response to carbohydrate;GO:0021536//diencephalon development;GO:0006875//cellular metal ion homeostasis;GO:0070555//response to interleukin-1;GO:0045838//positive regulation of membrane potential;GO:0001501//skeletal system development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0007006//mitochondrial membrane organization;GO:0051726//regulation of cell cycle;GO:0001783//B cell apoptotic process;GO:0035879//plasma membrane lactate transport;GO:0010212//response to ionizing radiation;GO:0008637//apoptotic mitochondrial changes;GO:0050877//neurological system process;GO:0008285//negative regulation of cell proliferation;GO:0016568//chromatin modification;GO:0006754//ATP biosynthetic process;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006974//cellular response to DNA damage stimulus;GO:0042471//ear morphogenesis;GO:0031325//positive regulation of cellular metabolic process;GO:0007519//skeletal muscle tissue development;GO:0010829//negative regulation of glucose transport;GO:0043393//regulation of protein binding;GO:0043627//response to estrogen;GO:0009967//positive regulation of signal transduction;GO:0009411//response to UV;GO:0010383;GO:0010243//response to organonitrogen compound;GO:0000723//telomere maintenance;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0019048//modulation by virus of host morphology or physiology;GO:0042493//response to drug;GO:0051604//protein maturation;GO:0006119//oxidative phosphorylation;GO:0044093;GO:0009698//phenylpropanoid metabolic process;GO:0006096//glycolytic process;GO:0000737//DNA catabolic process, endonucleolytic;GO:0000085//mitotic G2 phase;GO:0060070//canonical Wnt signaling pathway;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0009743//response to carbohydrate;GO:0021536//diencephalon development;GO:0006875//cellular metal ion homeostasis;GO:0070555//response to interleukin-1;GO:0045838//positive regulation of membrane potential;GO:0001501//skeletal system development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0007006//mitochondrial membrane organization;GO:0051726//regulation of cell cycle;GO:0001783//B cell apoptotic process;GO:0035879//plasma membrane lactate transport;GO:0010212//response to ionizing radiation;GO:0008637//apoptotic mitochondrial changes;GO:0050877//neurological system process;GO:0008285//negative regulation of cell proliferation;GO:0016568//chromatin modification;GO:0006754//ATP biosynthetic process;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006974//cellular response to DNA damage stimulus;GO:0042471//ear morphogenesis;GO:0031325//positive regulation of cellular metabolic process;GO:0007519//skeletal muscle tissue development;GO:0010829//negative regulation of glucose transport;GO:0043393//regulation of protein binding;GO:0043627//response to estrogen;GO:0009967//positive regulation of signal transduction;GO:0009411//response to UV;GO:0010383;GO:0010243//response to organonitrogen compound;GO:0000723//telomere maintenance;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0019048//modulation by virus of host morphology or physiology;GO:0042493//response to drug;GO:0051604//protein maturation;GO:0006119//oxidative phosphorylation;GO:0044093;GO:0009698//phenylpropanoid metabolic process;GO:0006096//glycolytic process;GO:0000737//DNA catabolic process, endonucleolytic;GO:0000085//mitotic G2 phase;GO:0060070//canonical Wnt signaling pathway;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0009743//response to carbohydrate;GO:0021536//diencephalon development;GO:0006875//cellular metal ion homeostasis;GO:0070555//response to interleukin-1;GO:0045838//positive regulation of membrane potential;GO:0001501//skeletal system development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0007006//mitochondrial membrane organization;GO:0051726//regulation of cell cycle;GO:0001783//B cell apoptotic process;GO:0035879//plasma membrane lactate transport;GO:0010212//response to ionizing radiation;GO:0008637//apoptotic mitochondrial changes;GO:0050877//neurological system process;GO:0008285//negative regulation of cell proliferation;GO:0016568//chromatin modification;GO:0006754//ATP biosynthetic process;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006974//cellular response to DNA damage stimulus;GO:0042471//ear morphogenesis;GO:0031325//positive regulation of cellular metabolic process;GO:0007519//skeletal muscle tissue development;GO:0010829//negative regulation of glucose transport;GO:0043393//regulation of protein binding;GO:0043627//response to estrogen;GO:0009967//positive regulation of signal transduction;GO:0009411//response to UV;GO:0010383;GO:0010243//response to organonitrogen compound;GO:0000723//telomere maintenance;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0019048//modulation by virus of host morphology or physiology;GO:0042493//response to drug;GO:0051604//protein maturation;GO:0006119//oxidative phosphorylation;GO:0044093;GO:0009698//phenylpropanoid metabolic process;GO:0006096//glycolytic process" gi|293629267|ref|NP_001170824.1|/0/myc proto-oncogene protein isoform c [Mus musculus] 13360 2845 2.97 3.063333333 0.04463943 Up 0.1143518 Dhcr7 7-dehydrocholesterol reductase K00213|1|0.0|947|mmu:13360|7-dehydrocholesterol reductase [EC:1.3.1.21] GO:0031224//intrinsic component of membrane;GO:0031965//nuclear membrane "GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor" GO:0030323//respiratory tube development;GO:0048869//cellular developmental process;GO:0040007//growth;GO:0001944//vasculature development;GO:0008283//cell proliferation;GO:0006695//cholesterol biosynthetic process gi|755524052|ref|XP_006508539.2|/0/PREDICTED: 7-dehydrocholesterol reductase isoform X2 [Mus musculus] 14057 2811 3.423333333 3.51 0.036069255 Up 0.1143518 Sfxn1 sideroflexin 1 K03351|1|2e-95|353|smm:Smp_136960|anaphase-promoting complex subunit 4;K02542|2|2e-15|87.8|pxy:105395647|DNA replication licensing factor MCM6 [EC:3.6.4.12] GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0005740//mitochondrial envelope GO:0015075//ion transmembrane transporter activity GO:0055080//cation homeostasis;GO:0000041//transition metal ion transport;GO:0030099//myeloid cell differentiation gi|15147224|ref|NP_081600.1|/7.62866e-167/sideroflexin-1 [Mus musculus] 230767 2213 3.6 3.693333333 0.036926569 Up 0.1143518 Iqcc IQ motif containing C - - - - gi|124126983|ref|NP_932143.2|/0/IQ domain-containing protein C [Mus musculus] 52440 3307 20.76 20.47666667 -0.019825561 Down 0.114332995 Tax1bp1 Tax1 (human T cell leukemia virus type I) binding protein 1 K20282|1|5e-19|99.8|crg:105342939|GRIP and coiled-coil domain-containing protein 2;K16464|5|2e-18|97.4|ola:101166347|centrosomal protein CEP250 GO:0044464 GO:0046914//transition metal ion binding;GO:0019899//enzyme binding;GO:0032182//ubiquitin-like protein binding GO:0006915//apoptotic process;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity gi|256773241|ref|NP_080092.2|/0/tax1-binding protein 1 homolog [Mus musculus] 15926 2270 24.54666667 24.82666667 0.016363446 Up 0.114332995 Idh1 "isocitrate dehydrogenase 1 (NADP+), soluble" K00031|1|0.0|798|mmu:15926|isocitrate dehydrogenase [EC:1.1.1.42] GO:0042579//microbody;GO:0042579//microbody GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0004448//isocitrate dehydrogenase activity;GO:0000166//nucleotide binding GO:0009725//response to hormone;GO:0043648//dicarboxylic acid metabolic process;GO:0006790//sulfur compound metabolic process;GO:0044262//cellular carbohydrate metabolic process;GO:0072350//tricarboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0008406//gonad development;GO:0006950//response to stress;GO:0009725//response to hormone;GO:0043648//dicarboxylic acid metabolic process;GO:0006790//sulfur compound metabolic process;GO:0044262//cellular carbohydrate metabolic process;GO:0072350//tricarboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0008406//gonad development;GO:0006950//response to stress gi|26352311|dbj|BAC39792.1|/0/unnamed protein product [Mus musculus] 23989 3427 26.43333333 26.71333333 0.015201644 Up 0.114332995 Med24 mediator complex subunit 24 K15167|1|0.0|1874|mmu:23989|mediator of RNA polymerase II transcription subunit 24 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0003712//transcription cofactor activity;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0008134//transcription factor binding;GO:0008080//N-acetyltransferase activity" GO:0006366//transcription from RNA polymerase II promoter;GO:0016570//histone modification;GO:0051259//protein oligomerization;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0032502//developmental process "gi|148684214|gb|EDL16161.1|/0/thyroid hormone receptor associated protein 4, isoform CRA_a, partial [Mus musculus]" 319727 2711 0.216666667 0.186666667 -0.215012891 Down 0.114267178 A330035P11Rik RIKEN cDNA A330035P11 gene - - - - - 17444 5428.47 0.16 0.186666667 0.222392421 Up 0.114267178 Grap2 GRB2-related adaptor protein 2 K07366|1|6e-172|608|mmu:17444|GRB2-related adaptor protein 2 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - - gi|6754722|ref|NP_034945.1|/4.79935e-171/GRB2-related adaptor protein 2 [Mus musculus] 320632 6740 16.19 16.46 0.02386135 Up 0.114126142 Snrnp200 small nuclear ribonucleoprotein 200 (U5) K12854|1|0.0|4036|mmu:320632|pre-mRNA-splicing helicase BRR2 [EC:3.6.4.13] GO:0030532//small nuclear ribonucleoprotein complex;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen "GO:0032550;GO:0042623//ATPase activity, coupled;GO:0003724//RNA helicase activity" GO:0000245//spliceosomal complex assembly "gi|148696230|gb|EDL28177.1|/0/activating signal cointegrator 1 complex subunit 3-like 1, isoform CRA_c, partial [Mus musculus]" 94186 3918.6 18.08 18.35333333 0.021647431 Up 0.114126142 Strn3 "striatin, calmodulin binding protein 3" K17608|1|0.0|1390|mmu:94186|striatin 1/3/4 - - - - 12229 2535 0.386666667 0.423333333 0.130703692 Up 0.113891083 Btk Bruton agammaglobulinemia tyrosine kinase K07370|1|0.0|1298|mmu:12229|Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2] GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0044425;GO:0044444//cytoplasmic part GO:0004713//protein tyrosine kinase activity;GO:0008289//lipid binding;GO:0032550;GO:0005515//protein binding;GO:0043169//cation binding;GO:0043168//anion binding GO:0021700//developmental maturation;GO:0009888//tissue development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0019932//second-messenger-mediated signaling;GO:0050851//antigen receptor-mediated signaling pathway;GO:0002441;GO:0001783//B cell apoptotic process;GO:0006979//response to oxidative stress;GO:0030183//B cell differentiation;GO:0002368//B cell cytokine production;GO:0002224//toll-like receptor signaling pathway;GO:0006468//protein phosphorylation gi|795281004|ref|XP_011820173.1|/0/PREDICTED: tyrosine-protein kinase BTK isoform X1 [Mandrillus leucophaeus] 212965 1631 0.416666667 0.38 -0.13289427 Down 0.113891083 BC024386 cDNA sequence BC023486 "K03847|1|2e-08|63.2|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - - 26568 2290 0.47 0.513333333 0.127235188 Up 0.113891083 Slc27a3 "solute carrier family 27 (fatty acid transporter), member 3" "K08772|1|0.0|1183|mmu:26568|solute carrier family 27 (fatty acid transporter), member 3 [EC:6.2.1.-]" - - - - 76829 1774 0.42 0.46 0.131244533 Up 0.113891083 Dok5 docking protein 5 K14752|1|1e-14|84.3|pbi:103059880|docking protein 1 - "GO:0004871//signal transducer activity;GO:0008289//lipid binding;GO:0005102//receptor binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0004871//signal transducer activity;GO:0008289//lipid binding;GO:0005102//receptor binding;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0048731//system development;GO:0006796//phosphate-containing compound metabolic process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0048731//system development;GO:0006796//phosphate-containing compound metabolic process;GO:0007167//enzyme linked receptor protein signaling pathway gi|255069730|ref|NP_084037.3|/5.48048e-178/docking protein 5 isoform 1 [Mus musculus] 270152 2472 0.376666667 0.413333333 0.134017348 Up 0.113891083 Amica1 "adhesion molecule, interacts with CXADR antigen 1" "K06539|1|3e-09|66.6|ngi:103749236|poliovirus receptor;K06522|2|4e-08|63.2|cmk:103180165|immunoglobulin superfamily, member 2/3;K06788|4|6e-06|55.8|phi:102101898|coxsackievirus and adenovirus receptor;K19511|5|7e-06|55.5|acs:100555993|peroxidase [EC:1.11.1.7]" - - - gi|160333187|ref|NP_001005421.3|/0/junctional adhesion molecule-like precursor [Mus musculus] 15203 4444.56 0.456666667 0.5 0.130786608 Up 0.113891083 Heph hephaestin K14735|1|0.0|1646|mmu:15203|hephaestin [EC:1.16.3.1] GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0003824//catalytic activity GO:0030099//myeloid cell differentiation;GO:0044710;GO:0000041//transition metal ion transport;GO:0006875//cellular metal ion homeostasis;GO:0030099//myeloid cell differentiation;GO:0055080//cation homeostasis;GO:0000041//transition metal ion transport;GO:0030099//myeloid cell differentiation;GO:0044710;GO:0000041//transition metal ion transport;GO:0006875//cellular metal ion homeostasis;GO:0030099//myeloid cell differentiation;GO:0044710;GO:0000041//transition metal ion transport;GO:0006875//cellular metal ion homeostasis "gi|148682267|gb|EDL14214.1|/0/hephaestin, isoform CRA_a, partial [Mus musculus]" 77744 2293 0.383333333 0.42 0.131789873 Up 0.113891083 Bora "bora, aurora kinase A activator" K16831|1|0.0|960|mmu:77744|protein aurora borealis - GO:0019900//kinase binding GO:0008104//protein localization;GO:0007052//mitotic spindle organization;GO:0007067//mitotic nuclear division "gi|148668129|gb|EDL00459.1|/0/RIKEN cDNA 6720463M24, isoform CRA_d, partial [Mus musculus]" 58242 2649 0.51 0.466666667 -0.128104826 Down 0.113891083 Nudt11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 K07766|1|5e-67|258|ngi:103730283|diphosphoinositol-polyphosphate diphosphatase [EC:3.6.1.52] GO:0044424 GO:0052842//inositol diphosphate pentakisphosphate diphosphatase activity;GO:0052841//inositol bisdiphosphate tetrakisphosphate diphosphatase activity;GO:0043169//cation binding - gi|674041730|ref|XP_008826692.1|/4.1591e-66/PREDICTED: diphosphoinositol polyphosphate phosphohydrolase 3-alpha isoform X1 [Nannospalax galili] 27215 3523.31 15.10333333 15.36 0.024311226 Up 0.113862876 Azi2 5-azacytidine induced gene 2 K12651|1|0.0|820|mmu:27215|5-azacytidine-induced protein 2 GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle - - "gi|148677311|gb|EDL09258.1|/0/5-azacytidine induced gene 2, isoform CRA_b, partial [Mus musculus]" 13728 4523.11 18.05666667 18.32 0.020887913 Up 0.113862876 Mark2 MAP/microtubule affinity regulating kinase 2 K08798|1|0.0|1482|mmu:13728|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] - - - - 16865 1982.64 19.63333333 19.37333333 -0.019232931 Down 0.113862876 Eif2d eukaryotic translation initiation factor 2D K15027|1|0.0|1030|mmu:16865|translation initiation factor 2D GO:0044424;GO:0044424 "GO:0008135//translation factor activity, RNA binding;GO:0008135//translation factor activity, RNA binding" GO:0006412//translation;GO:0006412//translation "gi|148707770|gb|EDL39717.1|/0/ligatin, isoform CRA_c, partial [Mus musculus]" 67472 2854.51 18.06666667 18.32333333 0.020351628 Up 0.113862876 Mtfr1 mitochondrial fission regulator 1 K13087|1|4e-23|98.2|gga:421691|bcl2 associated transcription factor 1 GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0007005//mitochondrion organization;GO:0045333//cellular respiration;GO:0007005//mitochondrion organization;GO:0045333//cellular respiration;GO:0007005//mitochondrion organization;GO:0045333//cellular respiration;GO:0007005//mitochondrion organization;GO:0045333//cellular respiration gi|22267450|ref|NP_080458.1|/1.71499e-174/mitochondrial fission regulator 1 [Mus musculus] 15312 1200 22.47666667 22.22 -0.01656928 Down 0.113862876 Hmgn1 high mobility group nucleosomal binding domain 1 K11299|1|3e-21|105|mmu:15312|high-mobility group nucleosome-binding domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0009411//response to UV;GO:0006289//nucleotide-excision repair;GO:0051276//chromosome organization;GO:0050793//regulation of developmental process;GO:0031077//post-embryonic camera-type eye development;GO:0042127//regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter "gi|119630061|gb|EAX09656.1|/1.22635e-27/high-mobility group nucleosome binding domain 1, isoform CRA_g [Homo sapiens]" 11798 5936.15 5.37 5.25 -0.032604665 Down 0.113834668 Xiap X-linked inhibitor of apoptosis K04725|1|0.0|1017|mmu:11798|E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27] GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0019787//ubiquitin-like protein transferase activity GO:0032446//protein modification by small protein conjugation;GO:0033554//cellular response to stress;GO:0030177//positive regulation of Wnt signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0033554//cellular response to stress;GO:0030177//positive regulation of Wnt signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0033554//cellular response to stress;GO:0030177//positive regulation of Wnt signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0032446//protein modification by small protein conjugation;GO:0033554//cellular response to stress;GO:0030177//positive regulation of Wnt signaling pathway;GO:0043066//negative regulation of apoptotic process gi|755564846|ref|XP_011249278.1|/1.45634e-109/PREDICTED: E3 ubiquitin-protein ligase XIAP isoform X2 [Mus musculus] 26432 3703.22 5.276666667 5.4 0.033332558 Up 0.113834668 Plod2 "procollagen lysine, 2-oxoglutarate 5-dioxygenase 2" "K13645|1|0.0|1466|mmu:26432|procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 [EC:1.14.11.4]" GO:0005789//endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane "GO:0070815//peptidyl-lysine 5-dioxygenase activity;GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0070815//peptidyl-lysine 5-dioxygenase activity;GO:0046914//transition metal ion binding;GO:0019842//vitamin binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0009725//response to hormone;GO:0006950//response to stress;GO:0009725//response to hormone;GO:0006950//response to stress "gi|218931167|ref|NP_001136388.1|/0/procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 isoform 1 precursor [Mus musculus]" 98956 3856 6.463333333 6.34 -0.027795557 Down 0.113834668 Nat10 N-acetyltransferase 10 K14521|1|0.0|1703|mmu:98956|N-acetyltransferase 10 [EC:2.3.1.-] GO:0031981//nuclear lumen GO:0016407//acetyltransferase activity;GO:0032550 - gi|23346561|ref|NP_694766.1|/0/RNA cytidine acetyltransferase [Mus musculus] 386612 1461 5.59 5.466666667 -0.032186874 Down 0.113834668 Thoc6 THO complex 6 K13175|1|0.0|642|mmu:386612|THO complex subunit 6 GO:0000346//transcription export complex GO:0003676//nucleic acid binding GO:0006396//RNA processing;GO:0006406//mRNA export from nucleus gi|56605680|ref|NP_001008425.1|/0/THO complex subunit 6 homolog [Mus musculus] 22235 2461 5.236666667 5.116666667 -0.033444525 Down 0.113834668 Ugdh UDP-glucose dehydrogenase K00012|1|0.0|990|mmu:22235|UDPglucose 6-dehydrogenase [EC:1.1.1.22] GO:0044444//cytoplasmic part "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding" GO:0007369//gastrulation;GO:0009226//nucleotide-sugar biosynthetic process;GO:0006023 gi|6678499|ref|NP_033492.1|/0/UDP-glucose 6-dehydrogenase [Mus musculus] 26900 4640 5.203333333 5.323333333 0.032893775 Up 0.113834668 Ddx3y "DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked" K17642|1|0.0|1120|mmu:26900|ATP-dependent RNA helicase DDX3Y [EC:3.6.4.13];K11594|3|0.0|1048|umr:103680200|ATP-dependent RNA helicase DDX3X [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle "GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0032550" - gi|25141235|ref|NP_036138.1|/0/ATP-dependent RNA helicase DDX3Y [Mus musculus] 382450 3785 5.936666667 6.056666667 0.028870903 Up 0.113834668 Gm5177 glyceraldehyde-3-phosphate dehydrogenase pseudogene K00134|1|1e-143|273|mmu:14433|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] - - - - 22343 4137 5.153333333 5.033333333 -0.03399177 Down 0.113834668 Lin7c lin-7 homolog C (C. elegans) K19931|1|3e-97|359|chx:102180517|protein lin-7 GO:0043296//apical junction complex;GO:0044459;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane GO:0019904//protein domain specific binding GO:0016192//vesicle-mediated transport;GO:0045184//establishment of protein localization;GO:0001505//regulation of neurotransmitter levels gi|926710268|ref|XP_013825279.1|/2.86466e-96/PREDICTED: protein lin-7 homolog C [Capra hircus] 93762 4658 5.47 5.353333333 -0.031103346 Down 0.113834668 Smarca5 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5" K11654|1|0.0|1865|mmu:93762|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-] GO:0031010//ISWI-type complex;GO:0005694//chromosome GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding;GO:0003682//chromatin binding GO:0007275//multicellular organism development;GO:0034728//nucleosome organization;GO:0006342//chromatin silencing;GO:0006338//chromatin remodeling;GO:0009154//purine ribonucleotide catabolic process;GO:0006281//DNA repair gi|40254124|ref|NP_444354.2|/0/SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [Mus musculus] 17423 3907 5.2 5.323333333 0.033818284 Up 0.113834668 Ndst2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 K02577|1|0.0|1722|mmu:17423|heparan sulfate N-deacetylase/N-sulfotransferase NDST2 [EC:3.1.1.- 2.8.2.-] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system GO:0034483//heparan sulfate sulfotransferase activity;GO:0016787//hydrolase activity GO:0006024//glycosaminoglycan biosynthetic process;GO:0030166//proteoglycan biosynthetic process;GO:0001991//regulation of systemic arterial blood pressure by circulatory renin-angiotensin gi|113195688|ref|NP_034941.2|/0/bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 [Mus musculus] 347722 9581 5.973333333 5.853333333 -0.029277793 Down 0.113834668 Agap1 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 1" "K12491|1|0.0|1598|mmu:347722|Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3" GO:0044424;GO:0044424 GO:0046914//transition metal ion binding;GO:0032550;GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0046914//transition metal ion binding;GO:0032550;GO:0008047//enzyme activator activity;GO:0008289//lipid binding GO:0032012//regulation of ARF protein signal transduction;GO:0045184//establishment of protein localization;GO:0032012//regulation of ARF protein signal transduction;GO:0045184//establishment of protein localization "gi|80978937|ref|NP_001032213.1|/0/arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform 2 [Mus musculus]" 93671 4452.36 6.296666667 6.413333333 0.026486097 Up 0.113834668 Cd163 CD163 antigen K06545|1|0.0|2286|mmu:93671|CD163 antigen GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0038024//cargo receptor activity;GO:0038024//cargo receptor activity GO:0002526//acute inflammatory response;GO:0002526//acute inflammatory response gi|281371423|ref|NP_001163866.1|/0/scavenger receptor cysteine-rich type 1 protein M130 isoform 1 precursor [Mus musculus] 12747 2015.01 20.63 20.37666667 -0.017825755 Down 0.113609011 Clk1 CDC-like kinase 1 K08823|1|0.0|676|mmu:12747|CDC-like kinase [EC:2.7.12.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity GO:0006468//protein phosphorylation;GO:0008380//RNA splicing;GO:0006468//protein phosphorylation;GO:0008380//RNA splicing;GO:0006468//protein phosphorylation;GO:0008380//RNA splicing gi|111038135|ref|NP_001036099.1|/0/dual specificity protein kinase CLK1 [Mus musculus] 67300 6178 22.07333333 22.32 0.016032517 Up 0.113609011 Cltc "clathrin, heavy polypeptide (Hc)" K04646|1|0.0|3300|lve:103070798|clathrin heavy chain GO:0030117//membrane coat;GO:0005802//trans-Golgi network;GO:0015630//microtubule cytoskeleton;GO:0012510//trans-Golgi network transport vesicle membrane;GO:0005905//clathrin-coated pit;GO:0048770;GO:0042383//sarcolemma GO:0033218//amide binding;GO:0008092//cytoskeletal protein binding GO:0006898//receptor-mediated endocytosis;GO:0007052//mitotic spindle organization;GO:0015031//protein transport;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048193//Golgi vesicle transport;GO:0006935//chemotaxis;GO:0002478;GO:0000087//mitotic M phase gi|602727413|ref|XP_007449155.1|/0/PREDICTED: clathrin heavy chain 1 [Lipotes vexillifer] 70266 1944 23.26666667 23.01666667 -0.015585622 Down 0.113609011 Ccbl1 kynurenine aminotransferase 1 K00816|1|0.0|877|mmu:70266|kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64] GO:0031981//nuclear lumen;GO:0044429 GO:0043168//anion binding;GO:0070546;GO:0042802//identical protein binding;GO:0036137;GO:0070548;GO:0016846//carbon-sulfur lyase activity GO:0006575//cellular modified amino acid metabolic process;GO:0019439//aromatic compound catabolic process "gi|148676501|gb|EDL08448.1|/0/cysteine conjugate-beta lyase 1, isoform CRA_c, partial [Mus musculus]" 22200 2049.45 21.53333333 21.78666667 0.016873819 Up 0.113609011 Uba3 ubiquitin-like modifier activating enzyme 3 K10686|1|0.0|902|mmu:22200|ubiquitin-activating enzyme E1 C [EC:6.2.1.45] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0008641//small protein activating enzyme activity;GO:0032550;GO:0005102//receptor binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0046983//protein dimerization activity;GO:0008641//small protein activating enzyme activity;GO:0032550;GO:0005102//receptor binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0046983//protein dimerization activity;GO:0008641//small protein activating enzyme activity;GO:0032550;GO:0005102//receptor binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0046983//protein dimerization activity;GO:0008641//small protein activating enzyme activity;GO:0032550;GO:0005102//receptor binding;GO:0016879//ligase activity, forming carbon-nitrogen bonds;GO:0046983//protein dimerization activity" "GO:0000278//mitotic cell cycle;GO:0032446//protein modification by small protein conjugation;GO:0006351//transcription, DNA-templated;GO:0000278//mitotic cell cycle;GO:0032446//protein modification by small protein conjugation;GO:0006351//transcription, DNA-templated;GO:0000278//mitotic cell cycle;GO:0032446//protein modification by small protein conjugation;GO:0006351//transcription, DNA-templated;GO:0000278//mitotic cell cycle;GO:0032446//protein modification by small protein conjugation;GO:0006351//transcription, DNA-templated" gi|686661126|ref|NP_001288787.1|/0/NEDD8-activating enzyme E1 catalytic subunit isoform 4 [Mus musculus] 18028 8982.96 18.51333333 18.76333333 0.019351471 Up 0.113609011 Nfib nuclear factor I/B K09169|1|0.0|804|myd:102772342|nuclear factor I/B GO:0043231//intracellular membrane-bounded organelle;GO:0030424//axon;GO:0043231//intracellular membrane-bounded organelle;GO:0030424//axon;GO:0031981//nuclear lumen;GO:0030424//axon;GO:0043231//intracellular membrane-bounded organelle;GO:0030424//axon "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0043566//structure-specific DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0043566//structure-specific DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0043566//structure-specific DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0043566//structure-specific DNA binding" GO:0007411//axon guidance;GO:0006366//transcription from RNA polymerase II promoter;GO:0060916//mesenchymal cell proliferation involved in lung development;GO:0021730//trigeminal sensory nucleus development;GO:0060487//lung epithelial cell differentiation;GO:0051100//negative regulation of binding;GO:0006259//DNA metabolic process;GO:0050680//negative regulation of epithelial cell proliferation;GO:0021537//telencephalon development;GO:0007411//axon guidance;GO:0006366//transcription from RNA polymerase II promoter;GO:0060916//mesenchymal cell proliferation involved in lung development;GO:0021730//trigeminal sensory nucleus development;GO:0060487//lung epithelial cell differentiation;GO:0051100//negative regulation of binding;GO:0006259//DNA metabolic process;GO:0050680//negative regulation of epithelial cell proliferation;GO:0021537//telencephalon development;GO:0007411//axon guidance;GO:0006366//transcription from RNA polymerase II promoter;GO:0060916//mesenchymal cell proliferation involved in lung development;GO:0021730//trigeminal sensory nucleus development;GO:0060487//lung epithelial cell differentiation;GO:0051100//negative regulation of binding;GO:0006259//DNA metabolic process;GO:0050680//negative regulation of epithelial cell proliferation;GO:0021537//telencephalon development;GO:0007606//sensory perception of chemical stimulus;GO:0007411//axon guidance;GO:0006366//transcription from RNA polymerase II promoter;GO:0060916//mesenchymal cell proliferation involved in lung development;GO:0021730//trigeminal sensory nucleus development;GO:0060487//lung epithelial cell differentiation;GO:0051100//negative regulation of binding;GO:0006259//DNA metabolic process;GO:0050680//negative regulation of epithelial cell proliferation;GO:0021537//telencephalon development gi|163965420|ref|NP_001106680.1|/0/nuclear factor 1 B-type isoform 1 [Mus musculus] 114896 4288 19.86666667 19.61666667 -0.018269915 Down 0.113609011 Afg3l1 AFG3-like AAA ATPase 1 K08956|1|0.0|968|mmu:114896|AFG3 family protein [EC:3.4.24.-] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle "GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0032550;GO:0046914//transition metal ion binding;GO:0016462//pyrophosphatase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0032550;GO:0046914//transition metal ion binding;GO:0016462//pyrophosphatase activity" GO:0007007//inner mitochondrial membrane organization;GO:0009057//macromolecule catabolic process;GO:0016485//protein processing;GO:0007007//inner mitochondrial membrane organization;GO:0009057//macromolecule catabolic process;GO:0016485//protein processing gi|66792806|ref|NP_473411.2|/0/AFG3-like protein 1 [Mus musculus] 433182 1791 19.29 19.53666667 0.018331193 Up 0.113609011 Eno1b "enolase 1B, retrotransposed" K01689|1|0.0|858|xla:100037034|enolase [EC:4.2.1.11] GO:0031988//membrane-bounded vesicle;GO:0044424;GO:0043234//protein complex;GO:0019898//extrinsic component of membrane;GO:0042995//cell projection GO:0046983//protein dimerization activity;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0016836//hydro-lyase activity "GO:0006351//transcription, DNA-templated;GO:0051707//response to other organism;GO:0006007//glucose catabolic process;GO:0001101//response to acid chemical;GO:0044093;GO:0016049//cell growth" "gi|70794816|ref|NP_001020559.1|/0/enolase 1B, retrotransposed [Mus musculus]" 224250 2143 15.71 15.46 -0.023142861 Down 0.113609011 Cldnd1 claudin domain containing 1 - GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane - - gi|356995848|ref|NP_001239379.1|/2.08239e-161/claudin domain-containing protein 1 isoform 2 [Mus musculus] 544817 4061.31 14.59666667 14.85 0.024823982 Up 0.113609011 Arhgap27 Rho GTPase activating protein 27 K01556|1|3e-68|263|xtr:100485536|kynureninase [EC:3.7.1.3];K20315|2|1e-33|148|aec:105149722|Rho GTPase-activating protein 21/23 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0019904//protein domain specific binding;GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0008289//lipid binding GO:0006897//endocytosis;GO:0006897//endocytosis;GO:0006897//endocytosis gi|187952861|gb|AAI38294.1|/2.13056e-130/5730442P18Rik protein [Mus musculus] 11428 4319 13.77666667 14.01333333 0.024573306 Up 0.113251721 Aco1 aconitase 1 K01681|1|0.0|1722|mmu:11428|aconitate hydratase [EC:4.2.1.3] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0003729//mRNA binding;GO:0051536//iron-sulfur cluster binding;GO:0003994//aconitate hydratase activity GO:0006412//translation;GO:0010039//response to iron ion;GO:0006875//cellular metal ion homeostasis;GO:0072350//tricarboxylic acid metabolic process;GO:0009060//aerobic respiration;GO:0007275//multicellular organism development;GO:0022600//digestive system process gi|110347487|ref|NP_031412.2|/0/cytoplasmic aconitate hydratase [Mus musculus] 241919 8869 2.08 2.013333333 -0.04699748 Down 0.113185904 Slc7a14 "solute carrier family 7 (cationic amino acid transporter, y+ system), member 14" "K13871|1|0.0|1321|mmu:241919|solute carrier family 7 (cationic amino acid transporter), member 14" GO:0031224//intrinsic component of membrane GO:0046943//carboxylic acid transmembrane transporter activity GO:0010921//regulation of phosphatase activity;GO:0006865//amino acid transport gi|50511019|dbj|BAD32495.1|/0/mKIAA1613 protein [Mus musculus] 116940 4389 2.026666667 2.1 0.051280505 Up 0.113185904 Tgs1 trimethylguanosine synthase 1 K14292|1|0.0|1643|mmu:116940|trimethylguanosine synthase [EC:2.1.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0008173//RNA methyltransferase activity;GO:0005488//binding "GO:0001510//RNA methylation;GO:0036260;GO:0006351//transcription, DNA-templated" gi|227496324|ref|NP_473430.3|/0/trimethylguanosine synthase [Mus musculus] 68067 1168 2.173333333 2.246666667 0.047876627 Up 0.113185904 3010026O09Rik RIKEN cDNA 3010026O09 gene - - - - gi|238550122|ref|NP_080819.2|/0/UPF0544 protein C5orf45 homolog [Mus musculus] 72584 5020 2.353333333 2.28 -0.045671858 Down 0.113185904 Cul4b cullin 4B K10609|1|0.0|1613|mmu:72584|cullin 4 GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0080008//Cul4-RING E3 ubiquitin ligase complex GO:0044389//ubiquitin-like protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding GO:0000084//mitotic S phase;GO:0006259//DNA metabolic process;GO:0009896;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process;GO:0000084//mitotic S phase;GO:0006259//DNA metabolic process;GO:0009896;GO:0033554//cellular response to stress;GO:0019941//modification-dependent protein catabolic process gi|158635985|ref|NP_001103612.1|/0/cullin-4B [Mus musculus] 328274 3331 1.886666667 1.816666667 -0.054545823 Down 0.113185904 Zfp459 zinc finger protein 459 K09228|1|9e-162|573|mmu:328274|KRAB domain-containing zinc finger protein - GO:0043169//cation binding "GO:0006351//transcription, DNA-templated;GO:0003006//developmental process involved in reproduction" gi|568983426|ref|XP_006517344.1|/1.28981e-176/PREDICTED: zinc finger protein 459 isoform X2 [Mus musculus] 237465 3655 2.136666667 2.07 -0.045731088 Down 0.113185904 Ccdc38 coiled-coil domain containing 38 - - - - gi|31541988|ref|NP_780697.2|/0/coiled-coil domain-containing protein 38 [Mus musculus] 14369 4840 2.083333333 2.013333333 -0.04930764 Down 0.113185904 Fzd7 frizzled class receptor 7 K02432|1|0.0|1270|ocu:103348917|frizzled 1/7 - - - - 72145 14277 2.21 2.283333333 0.047095118 Up 0.113185904 Wdfy3 WD repeat and FYVE domain containing 3 K18953|1|1e-84|320|bfo:BRAFLDRAFT_100614|factor associated with neutral sphingomyelinase activation GO:0044424 GO:0035091//phosphatidylinositol binding;GO:0043169//cation binding;GO:0016740//transferase activity - gi|39930599|ref|NP_766470.2|/0/WD repeat and FYVE domain-containing protein 3 [Mus musculus] 73473 9623 2.04 1.97 -0.050373523 Down 0.113185904 Iws1 IWS1 homolog (S. cerevisiae) K17498|1|0.0|1189|mmu:73473|transcription factor SPN1 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0010467//gene expression "gi|148664636|gb|EDK97052.1|/0/IWS1 homolog (S. cerevisiae), isoform CRA_b, partial [Mus musculus]" 50784 1604 1.006666667 0.953333333 -0.078533403 Down 0.113054271 Plpp2 phospholipid phosphatase 2 K01080|1|1e-140|502|mmu:50784|phosphatidate phosphatase [EC:3.1.3.4] - - - - 100141474 1425 1.01 0.956666667 -0.078267057 Down 0.113054271 4933428G20Rik RIKEN cDNA 4933428G20 gene K20315|1|3e-37|158|mmu:58996|Rho GTPase-activating protein 21/23 - - - "gi|148684134|gb|EDL16081.1|/1.15039e-55/mCG146189, partial [Mus musculus]" 53321 5360 0.89 0.84 -0.083416008 Down 0.113054271 Cntnap1 contactin associated protein-like 1 K07379|1|0.0|2680|mmu:53321|contactin associated protein 1 GO:0033267;GO:0005887//integral component of plasma membrane GO:0019904//protein domain specific binding GO:0008366//axon ensheathment;GO:0007043//cell-cell junction assembly;GO:0050905//neuromuscular process;GO:0006996//organelle organization;GO:0022610;GO:0031175//neuron projection development;GO:0034613//cellular protein localization;GO:0010970//transport along microtubule "gi|148671949|gb|EDL03896.1|/0/contactin associated protein 1, isoform CRA_a, partial [Mus musculus]" 78798 5125 0.906666667 0.96 0.08246216 Up 0.113054271 Eml4 echinoderm microtubule associated protein like 4 K15420|1|0.0|1865|mmu:78798|echinoderm microtubule-associated protein-like 4 GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton;GO:0015630//microtubule cytoskeleton - - gi|167234435|ref|NP_001107833.1|/0/echinoderm microtubule-associated protein-like 4 isoform 1 [Mus musculus] 100043314 963 0.863333333 0.913333333 0.081223795 Up 0.113054271 Tigit T cell immunoreceptor with Ig and ITIM domains K16350|1|6e-131|469|mmu:100043314|T-cell immunoreceptor with Ig and ITIM domains - - - - 69862 2302 0.85 0.803333333 -0.081464101 Down 0.113054271 1810064F22Rik RIKEN cDNA 1810064F22 gene "K10279|1|5e-18|95.9|fpg:101911127|F-box and leucine-rich repeat protein 13;K14684|2|5e-17|72.4|ngi:103726559|solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41" - - - - 100526505 88 0.986666667 0.936666667 -0.075027045 Down 0.113054271 Mir3101 microRNA 3101 - - - - - 231474 1375 0.9 0.853333333 -0.076815597 Down 0.113054271 Paqr3 progestin and adipoQ receptor family member III K07297|1|2e-31|139|cqu:CpipJ_CPIJ002779|adiponectin receptor GO:0031224//intrinsic component of membrane - - gi|38259216|ref|NP_940814.1|/3.53089e-179/progestin and adipoQ receptor family member 3 [Mus musculus] 17229 1088 0.873333333 0.923333333 0.080319165 Up 0.113054271 Tpsb2 tryptase beta 2 K01340|1|3e-160|566|mmu:17229|tryptase [EC:3.4.21.59] GO:0044421 GO:0004175//endopeptidase activity;GO:0005539//glycosaminoglycan binding GO:0043062//extracellular structure organization;GO:0019538//protein metabolic process;GO:0006952//defense response;GO:0022411 gi|130496076|ref|NP_034911.3|/2.8551e-159/tryptase beta-2 precursor [Mus musculus] 17309 4682 0.85 0.9 0.08246216 Up 0.113054271 Mgat3 mannoside acetylglucosaminyltransferase 3 "K00737|1|0.0|1073|mmu:17309|beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.144]" GO:0031224//intrinsic component of membrane GO:0008375//acetylglucosaminyltransferase activity GO:0006486//protein glycosylation "gi|568991591|ref|XP_006520616.1|/0/PREDICTED: beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase isoform X2 [Mus musculus]" 27015 4226 0.963333333 0.913333333 -0.0768936 Down 0.113054271 Polk "polymerase (DNA directed), kappa" K03511|1|0.0|1662|mmu:27015|DNA polymerase kappa [EC:2.7.7.7] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003677//DNA binding;GO:0034061//DNA polymerase activity GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress gi|6753636|ref|NP_036178.1|/0/DNA polymerase kappa [Mus musculus] 213011 2765 0.25 0.216666667 -0.206450877 Down 0.112950844 Zfp583 zinc finger protein 583 K09228|1|0.0|1160|mmu:213011|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|85701750|ref|NP_001028421.1|/0/zinc finger protein 583 [Mus musculus] 60530 2964 0.173333333 0.2 0.206450877 Up 0.112950844 Fignl1 fidgetin-like 1 K13254|1|4e-93|345|pss:102457579|spastin [EC:3.6.4.3] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0032550;GO:0016462//pyrophosphatase activity;GO:0043169//cation binding;GO:0032550;GO:0016462//pyrophosphatase activity;GO:0043169//cation binding;GO:0032550;GO:0016462//pyrophosphatase activity GO:0001503//ossification;GO:0007049//cell cycle;GO:0006915//apoptotic process;GO:0008283//cell proliferation;GO:0009150//purine ribonucleotide metabolic process;GO:0001503//ossification;GO:0007049//cell cycle;GO:0006915//apoptotic process;GO:0008283//cell proliferation;GO:0009150//purine ribonucleotide metabolic process;GO:0001503//ossification;GO:0007049//cell cycle;GO:0006915//apoptotic process;GO:0008283//cell proliferation;GO:0009150//purine ribonucleotide metabolic process gi|568970393|ref|XP_006514830.1|/0/PREDICTED: fidgetin-like protein 1 isoform X2 [Mus musculus] 71950 2004 0.19 0.22 0.211504105 Up 0.112950844 Nanog Nanog homeobox K10164|1|5e-152|540|mmu:71950|homeobox protein Nanog GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding GO:0000278//mitotic cell cycle;GO:0048333//mesodermal cell differentiation;GO:0010453//regulation of cell fate commitment;GO:0008283//cell proliferation;GO:0051301//cell division;GO:0019827//stem cell population maintenance;GO:0001714//endodermal cell fate specification;GO:0033993//response to lipid;GO:0030509//BMP signaling pathway;GO:0000278//mitotic cell cycle;GO:0048333//mesodermal cell differentiation;GO:0010453//regulation of cell fate commitment;GO:0008283//cell proliferation;GO:0051301//cell division;GO:0019827//stem cell population maintenance;GO:0001714//endodermal cell fate specification;GO:0033993//response to lipid;GO:0030509//BMP signaling pathway;GO:0000278//mitotic cell cycle;GO:0048333//mesodermal cell differentiation;GO:0010453//regulation of cell fate commitment;GO:0008283//cell proliferation;GO:0051301//cell division;GO:0019827//stem cell population maintenance;GO:0001714//endodermal cell fate specification;GO:0033993//response to lipid;GO:0030509//BMP signaling pathway;GO:0000278//mitotic cell cycle;GO:0048333//mesodermal cell differentiation;GO:0010453//regulation of cell fate commitment;GO:0008283//cell proliferation;GO:0051301//cell division;GO:0019827//stem cell population maintenance;GO:0001714//endodermal cell fate specification;GO:0033993//response to lipid;GO:0030509//BMP signaling pathway gi|755517372|ref|XP_011239773.1|/2.19587e-158/PREDICTED: homeobox protein NANOG isoform X2 [Mus musculus] 71970 2492 0.193333333 0.223333333 0.208108195 Up 0.112950844 Zbed5 "zinc finger, BED type containing 5" K09228|1|8e-51|204|gja:107122456|KRAB domain-containing zinc finger protein;K11837|2|3e-21|106|bfo:BRAFLDRAFT_121867|ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12];K00933|3|4e-18|96.3|pss:102459236|creatine kinase [EC:2.7.3.2];K04257|4|7e-18|95.5|cmy:102941531|olfactory receptor;K09503|5|2e-11|74.3|pss:102449121|DnaJ homolog subfamily A member 2 - - - - 13363 4239 0.196666667 0.17 -0.210217707 Down 0.112950844 Dhh desert hedgehog K11990|1|0.0|666|mmu:13363|desert hedgehog GO:0016020//membrane GO:0046914//transition metal ion binding;GO:0005102//receptor binding;GO:0016787//hydrolase activity GO:0008366//axon ensheathment;GO:0007049//cell cycle;GO:0043627//response to estrogen;GO:0030908//protein splicing;GO:0007166//cell surface receptor signaling pathway;GO:0007281//germ cell development;GO:0006694//steroid biosynthetic process gi|6681181|ref|NP_031883.1|/0/desert hedgehog protein precursor [Mus musculus] 72230 3839 0.19 0.22 0.211504105 Up 0.112950844 Zfp558 zinc finger protein 558 K09228|1|0.0|864|mmu:72230|KRAB domain-containing zinc finger protein - - - gi|254692890|ref|NP_083211.1|/0/zinc finger protein 558 [Mus musculus] 20833 2839.45 21.65333333 21.88 0.015023606 Up 0.112838016 Ssrp1 structure specific recognition protein 1 K09272|1|0.0|1112|mmu:20833|structure-specific recognition protein 1 GO:0031981//nuclear lumen;GO:0043232;GO:0031981//nuclear lumen;GO:0043232 GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006351//transcription, DNA-templated;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006351//transcription, DNA-templated" gi|564341677|ref|XP_006234539.1|/0/PREDICTED: FACT complex subunit SSRP1 isoform X2 [Rattus norvegicus] 64010 2524 13.83333333 14.06666667 0.024131662 Up 0.112838016 Sav1 salvador family WW domain containing 1 K16686|1|0.0|774|mmu:64010|scaffold protein salvador GO:0043231//intracellular membrane-bounded organelle - GO:0051239;GO:0003281//ventricular septum development;GO:0035556//intracellular signal transduction;GO:0006915//apoptotic process;GO:0009913//epidermal cell differentiation;GO:0035265//organ growth;GO:0002065;GO:0008285//negative regulation of cell proliferation gi|11528514|ref|NP_071311.1|/0/protein salvador homolog 1 [Mus musculus] 218693 4610.65 16.35333333 16.12333333 -0.020434696 Down 0.112838016 Paip1 polyadenylate binding protein-interacting protein 1 K14322|1|0.0|781|mmu:218693|polyadenylate-binding protein-interacting protein 1 GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part "GO:0090079//translation regulator activity, nucleic acid binding;GO:0090079//translation regulator activity, nucleic acid binding" "GO:0006412//translation;GO:0043488//regulation of mRNA stability;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006412//translation;GO:0043488//regulation of mRNA stability;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" gi|21703908|ref|NP_663432.1|/0/polyadenylate-binding protein-interacting protein 1 isoform 1 [Mus musculus] 77697 3021 15.92333333 15.69666667 -0.020684154 Down 0.112838016 Mmab methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human) K00798|1|2e-110|403|mmu:77697|cob(I)alamin adenosyltransferase [EC:2.5.1.17] GO:0043231//intracellular membrane-bounded organelle "GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0032550" - "gi|21313396|ref|NP_084232.1|/1.5864e-109/cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial precursor [Mus musculus]" 230654 3146 13.35333333 13.58666667 0.02499163 Up 0.112838016 Lrrc41 leucine rich repeat containing 41 K10347|1|0.0|1326|mmu:230654|leucine-rich repeat-containing protein 41 - - - gi|819231695|ref|NP_705741.3|/0/leucine-rich repeat-containing protein 41 [Mus musculus] 58249 1227.72 20.82666667 20.59333333 -0.016254583 Down 0.112838016 Fibp fibroblast growth factor (acidic) intracellular binding protein - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0019838//growth factor binding;GO:0019838//growth factor binding GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|675702695|ref|XP_002755590.2|/0/PREDICTED: acidic fibroblast growth factor intracellular-binding protein isoform X2 [Callithrix jacchus] 56491 6969 21.64333333 21.41333333 -0.015413317 Down 0.112838016 Vapb "vesicle-associated membrane protein, associated protein B and C" K10707|1|1e-122|445|mmu:56491|vesicle-associated membrane protein-associated protein B GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0015631//tubulin binding GO:0006665//sphingolipid metabolic process;GO:0019079//viral genome replication;GO:0006796//phosphate-containing compound metabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0006875//cellular metal ion homeostasis gi|31543940|ref|NP_062780.2|/9.06736e-122/vesicle-associated membrane protein-associated protein B [Mus musculus] 16923 4285.84 17.17333333 17.40666667 0.019469864 Up 0.112838016 Sh2b3 SH2B adaptor protein 3 K12459|1|0.0|1023|mmu:16923|SH2B adaptor protein 1/3 - GO:0008289//lipid binding;GO:0005515//protein binding;GO:0043168//anion binding;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0043168//anion binding;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0043168//anion binding;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0043168//anion binding GO:0030097//hemopoiesis;GO:0007165//signal transduction;GO:0048869//cellular developmental process;GO:0030097//hemopoiesis;GO:0007165//signal transduction;GO:0048869//cellular developmental process;GO:0030097//hemopoiesis;GO:0007165//signal transduction;GO:0048869//cellular developmental process;GO:0030097//hemopoiesis;GO:0007165//signal transduction;GO:0048869//cellular developmental process "gi|149063392|gb|EDM13715.1|/0/rCG21617, isoform CRA_b [Rattus norvegicus]" 16590 5189 0.503333333 0.546666667 0.119147265 Up 0.112734589 Kit kit oncogene K05091|1|0.0|1844|mmu:16590|proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1] GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0030141//secretory granule;GO:0044421;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0030141//secretory granule;GO:0044421 GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032550;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0019899//enzyme binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032550;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0019899//enzyme binding GO:0010467//gene expression;GO:0030219//megakaryocyte differentiation;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0043405//regulation of MAP kinase activity;GO:0044093;GO:0002279;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048232//male gamete generation;GO:0006952//defense response;GO:0050931//pigment cell differentiation;GO:0002244//hematopoietic progenitor cell differentiation;GO:0032870//cellular response to hormone stimulus;GO:0090136//epithelial cell-cell adhesion;GO:0019221//cytokine-mediated signaling pathway;GO:0030595//leukocyte chemotaxis;GO:0031269//pseudopodium assembly;GO:0007219//Notch signaling pathway;GO:0002768//immune response-regulating cell surface receptor signaling pathway;GO:0006664//glycolipid metabolic process;GO:0061082;GO:0030183//B cell differentiation;GO:0007281//germ cell development;GO:0048522;GO:0008283//cell proliferation;GO:0008585//female gonad development;GO:0010631//epithelial cell migration;GO:0022604//regulation of cell morphogenesis;GO:0007632//visual behavior;GO:0002573//myeloid leukocyte differentiation;GO:0030036//actin cytoskeleton organization;GO:0017145//stem cell division;GO:0019827//stem cell population maintenance;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0012501//programmed cell death;GO:0010467//gene expression;GO:0030219//megakaryocyte differentiation;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0043405//regulation of MAP kinase activity;GO:0044093;GO:0002279;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048232//male gamete generation;GO:0006952//defense response;GO:0050931//pigment cell differentiation;GO:0002244//hematopoietic progenitor cell differentiation;GO:0032870//cellular response to hormone stimulus;GO:0090136//epithelial cell-cell adhesion;GO:0019221//cytokine-mediated signaling pathway;GO:0030595//leukocyte chemotaxis;GO:0031269//pseudopodium assembly;GO:0007219//Notch signaling pathway;GO:0002768//immune response-regulating cell surface receptor signaling pathway;GO:0006664//glycolipid metabolic process;GO:0061082;GO:0030183//B cell differentiation;GO:0007281//germ cell development;GO:0048522;GO:0008283//cell proliferation;GO:0008585//female gonad development;GO:0010631//epithelial cell migration;GO:0022604//regulation of cell morphogenesis;GO:0007632//visual behavior;GO:0002573//myeloid leukocyte differentiation;GO:0030036//actin cytoskeleton organization;GO:0017145//stem cell division;GO:0019827//stem cell population maintenance;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0012501//programmed cell death gi|170650719|ref|NP_066922.2|/0/mast/stem cell growth factor receptor Kit isoform 2 precursor [Mus musculus] 382118 2228 0.526666667 0.483333333 -0.123871658 Down 0.112734589 Zkscan7 zinc finger with KRAB and SCAN domains 7 K09230|1|0.0|1506|mmu:382118|SCAN domain-containing zinc finger protein;K09229|3|0.0|1064|cge:100764643|KRAB and SCAN domains-containing zinc finger protein - - - - 381678 2271 0.43 0.466666667 0.118055762 Up 0.112734589 Zcwpw1 "zinc finger, CW type with PWWP domain 1" K10362|1|2e-13|80.5|obi:106883030|myosin XVIII;K11424|2|1e-10|71.2|ngi:103741129|histone-lysine N-methyltransferase NSD2 [EC:2.1.1.43];K11425|4|3e-10|69.7|xma:102222572|histone-lysine N-methyltransferase NSD3 [EC:2.1.1.43] - GO:0046914//transition metal ion binding - gi|254553414|ref|NP_001005426.2|/0/zinc finger CW-type PWWP domain protein 1 [Mus musculus] 269152 7422 0.476666667 0.44 -0.115477217 Down 0.112734589 Kif26b kinesin family member 26B K10404|1|0.0|3446|mmu:269152|kinesin family member 26 - - - gi|239582737|ref|NP_001155137.1|/0/kinesin-like protein KIF26B [Mus musculus] 18973 7167 0.553333333 0.51 -0.117651589 Down 0.112734589 Pole "polymerase (DNA directed), epsilon" K02324|1|0.0|4478|mmu:18973|DNA polymerase epsilon subunit 1 [EC:2.7.7.7] GO:0000109//nucleotide-excision repair complex GO:0051536//iron-sulfur cluster binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0034061//DNA polymerase activity;GO:0036094//small molecule binding GO:0006281//DNA repair gi|195947387|ref|NP_035262.2|/0/DNA polymerase epsilon catalytic subunit A [Mus musculus] 100039436 3482 0.446666667 0.486666667 0.123735368 Up 0.112734589 Mageb16-ps1 "melanoma antigen family B, 16, pseudogene 1" K12464|1|4e-33|121|myd:102767390|melanoma-associated antigen D1 - - - gi|148682773|gb|EDL14720.1|/1.46164e-163/mCG60797 [Mus musculus] 106369 2879 0.456666667 0.42 -0.120752159 Down 0.112734589 Ypel1 yippee-like 1 (Drosophila) K04371|1|2e-06|57.4|asn:102375250|mitogen-activated protein kinase 1/3 [EC:2.7.11.24] - - GO:0042552//myelination gi|597517962|ref|NP_001277976.1|/4.44646e-112/protein yippee-like 1 isoform 1 [Mus musculus] 12934 4451 5.103333333 4.99 -0.032400061 Down 0.112602956 Dpysl2 dihydropyrimidinase-like 2 K07528|1|0.0|1115|rno:25416|dihydropyrimidinase-like 2 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0033267;GO:0044444//cytoplasmic part "GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0019900//kinase binding" GO:0014047//glutamate secretion;GO:0048638//regulation of developmental growth;GO:0006996//organelle organization;GO:0016192//vesicle-mediated transport;GO:0014070//response to organic cyclic compound;GO:0021988//olfactory lobe development;GO:0006206//pyrimidine nucleobase metabolic process;GO:0030182//neuron differentiation gi|40254595|ref|NP_034085.2|/0/dihydropyrimidinase-related protein 2 [Mus musculus] 103844 1109.31 5.803333333 5.69 -0.028453145 Down 0.112602956 Inca1 "inhibitor of CDK, cyclin A1 interacting protein 1" - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0006915//apoptotic process;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0008283//cell proliferation gi|47523979|ref|NP_998894.1|/4.48376e-119/protein INCA1 isoform 1 [Mus musculus] 72469 3031 5.86 5.973333333 0.027635567 Up 0.112602956 Plcd3 "phospholipase C, delta 3" "K05857|1|0.0|1450|mmu:72469|phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]" - - - gi|50511207|dbj|BAD32589.1|/0/mKIAA1964 protein [Mus musculus] 102644 2388 6.016666667 6.13 0.026922643 Up 0.112602956 Oaf out at first homolog "K09364|1|7e-27|125|umr:103662302|POU domain transcription factor, class 2" - - - "gi|148693603|gb|EDL25550.1|/6.77796e-137/DNA segment, Chr 9, University of California at Los Angeles 1, isoform CRA_a, partial [Mus musculus]" 14391 2718.9 4.823333333 4.71 -0.034303456 Down 0.112602956 Gabpb1 "GA repeat binding protein, beta 1" "K09454|1|7e-45|183|lcm:102353599|GA-binding protein transcription factor, beta" GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0000975//regulatory region DNA binding;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0046983//protein dimerization activity GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter "gi|148696213|gb|EDL28160.1|/2.58719e-180/GA repeat binding protein, beta 1, isoform CRA_b, partial [Mus musculus]" 407800 3626 5.81 5.7 -0.027576244 Down 0.112602956 Ecm2 "extracellular matrix protein 2, female organ and adipocyte specific" K08119|1|0.0|1226|mmu:407800|extracellular matrix protein 2 GO:0005578//proteinaceous extracellular matrix GO:0005518//collagen binding;GO:0005539//glycosaminoglycan binding GO:0043062//extracellular structure organization;GO:0010810//regulation of cell-substrate adhesion "gi|148709136|gb|EDL41082.1|/0/extracellular matrix protein 2, female organ and adipocyte specific, isoform CRA_b, partial [Mus musculus]" 105000 5792 1.386666667 1.45 0.064431873 Up 0.112593554 Dnal1 "dynein, axonemal, light chain 1" "K10411|1|3e-103|380|mmu:105000|dynein light chain 1, axonemal" - - - "gi|148670816|gb|EDL02763.1|/5.92975e-103/RIKEN cDNA 1700010H15, isoform CRA_a, partial [Mus musculus]" 11307 5821 1.466666667 1.406666667 -0.060260525 Down 0.112593554 Abcg1 "ATP-binding cassette, sub-family G (WHITE), member 1" "K05679|1|0.0|1202|mmu:11307|ATP-binding cassette, subfamily G (WHITE), member 1" - - - - 170772 5621.65 1.26 1.316666667 0.063466419 Up 0.112593554 Glcci1 glucocorticoid induced transcript 1 K10292|1|1e-123|253|mmu:67141|F-box protein 5 GO:0044424;GO:0044424;GO:0044424 - - "gi|148681984|gb|EDL13931.1|/7.48429e-172/mCG2776, isoform CRA_d, partial [Mus musculus]" 218100 4844 1.3 1.243333333 -0.064298493 Down 0.112593554 Zfp322a zinc finger protein 322A K09228|1|1e-99|368|tup:102475152|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|27369830|ref|NP_766174.1|/0/zinc finger protein 322 [Mus musculus] 240084 2676 1.236666667 1.293333333 0.064637466 Up 0.112593554 Cchcr1 coiled-coil alpha-helical rod protein 1 K16760|1|0.0|1169|mmu:240084|coiled-coil alpha-helical rod protein 1 GO:0043231//intracellular membrane-bounded organelle - GO:0006886//intracellular protein transport;GO:0048869//cellular developmental process "gi|148691273|gb|EDL23220.1|/0/coiled-coil alpha-helical rod protein 1, isoform CRA_b [Mus musculus]" 56839 4285 1.393333333 1.333333333 -0.063502942 Down 0.112593554 Lgi1 "leucine-rich repeat LGI family, member 1" K19999|1|0.0|846|lcm:102367021|leucine-rich repeat LGI family member 3 - - - gi|532017014|ref|XP_005352263.1|/0/PREDICTED: leucine-rich glioma-inactivated protein 1 [Microtus ochrogaster] 209003 1743 1.596666667 1.66 0.056120086 Up 0.112593554 Rbmx2 "RNA binding motif protein, X-linked 2" "K13107|1|4e-117|424|mmu:209003|RNA-binding motif protein, X-linked 2" - GO:0003676//nucleic acid binding - "gi|27734072|ref|NP_775552.1|/3.4102e-116/RNA-binding motif protein, X-linked 2 [Mus musculus]" 98376 2559.01 1.25 1.306666667 0.063963059 Up 0.112593554 Gorab "golgin, RAB6-interacting" K19748|1|1e-174|355|mmu:98376|RAB6-interacting golgin - - - - 67664 1334 1.553333333 1.493333333 -0.056831223 Down 0.112593554 Rnf125 ring finger protein 125 K12170|1|5e-92|340|rno:361296|E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27] GO:0044464 GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0032446//protein modification by small protein conjugation gi|73917575|sp|Q9D9R0.3|RN125_MOUSE/2.56013e-94/RecName: Full=E3 ubiquitin-protein ligase RNF125; AltName: Full=RING finger protein 125 327900 3056 1.39 1.453333333 0.064280751 Up 0.112593554 Ubtd2 ubiquitin domain containing 2 - GO:0031981//nuclear lumen - - gi|40254263|ref|NP_776145.2|/1.8257e-129/ubiquitin domain-containing protein 2 [Mus musculus] 77341 892 1.506666667 1.57 0.059404287 Up 0.112593554 9530026F06Rik RIKEN cDNA 9530026F06 gene - - - - "gi|148667745|gb|EDL00162.1|/1.32606e-41/mCG144499, partial [Mus musculus]" 27204 6861.37 0.21 0.183333333 -0.19592021 Down 0.112546542 Syn3 synapsin III K19941|1|1e-106|390|mmu:27204|synapsin GO:0008021//synaptic vesicle;GO:0008021//synaptic vesicle GO:0032550;GO:0032550 GO:0001505//regulation of neurotransmitter levels;GO:0001505//regulation of neurotransmitter levels gi|20514282|gb|AAM22969.1|/0/SYN3 [Mus musculus] 93717 4717 0.206666667 0.236666667 0.195550809 Up 0.112546542 Pcdhga9 "protocadherin gamma subfamily A, 9" K16495|1|0.0|1719|mmu:93717|protocadherin gamma subfamily A GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|18087769|ref|NP_291070.1|/0/protocadherin gamma-A9 precursor [Mus musculus] 20603 3377 15.01333333 14.79 -0.021622274 Down 0.112405506 Sms spermine synthase K00802|1|0.0|687|mmu:20603|spermine synthase [EC:2.5.1.22] GO:0044444//cytoplasmic part "GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups" GO:0006596//polyamine biosynthetic process;GO:0000096//sulfur amino acid metabolic process gi|118600998|ref|NP_033240.3|/0/spermine synthase [Mus musculus] 22323 2266.38 20.19 20.40666667 0.015399633 Up 0.112405506 Vasp vasodilator-stimulated phosphoprotein K06274|1|3e-75|285|mmu:22323|vasodilator-stimulated phosphoprotein GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0042995//cell projection;GO:0044424;GO:0016020//membrane;GO:0043232;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0042995//cell projection;GO:0016020//membrane;GO:0043232;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0042995//cell projection;GO:0016020//membrane;GO:0043232;GO:0031252//cell leading edge;GO:0005924//cell-substrate adherens junction;GO:0042995//cell projection;GO:0016020//membrane GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding GO:0006935//chemotaxis;GO:0030036//actin cytoskeleton organization;GO:0071822;GO:0007015//actin filament organization;GO:0051260//protein homooligomerization;GO:0006935//chemotaxis;GO:0007015//actin filament organization;GO:0051260//protein homooligomerization;GO:0006935//chemotaxis;GO:0007015//actin filament organization;GO:0051260//protein homooligomerization;GO:0006935//chemotaxis gi|74152357|dbj|BAE33933.1|/1.0003e-73/unnamed protein product [Mus musculus] 66072 3116 19.04333333 19.26666667 0.016820963 Up 0.112405506 Sdhaf2 succinate dehydrogenase complex assembly factor 2 K18168|1|1e-81|307|mmu:66072|succinate dehydrogenase assembly factor 2 GO:0031981//nuclear lumen - GO:0018065//protein-cofactor linkage;GO:0022904//respiratory electron transport chain "gi|148709410|gb|EDL41356.1|/8.21597e-85/RIKEN cDNA 0610038F07, isoform CRA_a, partial [Mus musculus]" 68626 2781 16.80333333 17.02666667 0.019048571 Up 0.112405506 Elac2 elaC ribonuclease Z 2 K00784|1|0.0|1621|mmu:68626|ribonuclease Z [EC:3.1.26.11] - - - - 223453 1481 14.15 14.37 0.022258009 Up 0.112405506 Dap death-associated protein - - GO:0019904//protein domain specific binding GO:0009267//cellular response to starvation;GO:0006915//apoptotic process;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0007165//signal transduction;GO:0006914//autophagy gi|22122539|ref|NP_666169.1|/4.78583e-52/death-associated protein 1 [Mus musculus] 67533 4893 12.97 12.75333333 -0.024304107 Down 0.112405506 Ppfibp1 "PTPRF interacting protein, binding protein 1 (liprin beta 1)" K19533|1|5e-10|70.5|nle:100592558|synaptonemal complex protein 1;K06267|2|6e-10|70.1|aqu:100640767|hyaluronan-mediated motility receptor;K11498|5|2e-09|68.6|spu:576192|centromeric protein E - - - gi|50510851|dbj|BAD32411.1|/0/mKIAA1230 protein [Mus musculus] 70790 9773 13.44666667 13.23 -0.023435522 Down 0.112405506 Ubr5 ubiquitin protein ligase E3 component n-recognin 5 K10593|1|0.0|4460|mmu:70790|E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26] - - - gi|163310753|ref|NP_001106192.1|/0/E3 ubiquitin-protein ligase UBR5 isoform 2 [Mus musculus] 29857 1905 15.04 15.26333333 0.021265497 Up 0.112405506 Mapk12 mitogen-activated protein kinase 12 K04441|1|0.0|740|mmu:29857|p38 MAP kinase [EC:2.7.11.24] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0046872//metal ion binding;GO:0004702//receptor signaling protein serine/threonine kinase activity "GO:0006468//protein phosphorylation;GO:0051726//regulation of cell cycle;GO:0042692//muscle cell differentiation;GO:0007165//signal transduction;GO:0006351//transcription, DNA-templated" gi|7305253|ref|NP_038899.1|/0/mitogen-activated protein kinase 12 [Mus musculus] 68778 2938 19.17 18.95 -0.016652489 Down 0.112405506 Gucd1 guanylyl cyclase domain containing 1 - - - - "gi|355563527|gb|EHH20089.1|/2.27541e-145/hypothetical protein EGK_02875, partial [Macaca mulatta]" 16363 2484 13.65 13.43333333 -0.023083613 Down 0.112405506 Irf2 interferon regulatory factor 2 K10153|1|0.0|674|mmu:16363|interferon regulatory factor 2 GO:0031981//nuclear lumen;GO:0005924//cell-substrate adherens junction GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated" gi|755525367|ref|XP_011240477.1|/0/PREDICTED: interferon regulatory factor 2 isoform X2 [Mus musculus] 100040724 1315 0.19 0.216666667 0.189477799 Up 0.112405506 Mirg miRNA containing gene - - - - "gi|148686739|gb|EDL18686.1|/4.96475e-42/mCG146212, partial [Mus musculus]" 223753 4562 15.10333333 14.88 -0.021492464 Down 0.112405506 Cerk ceramide kinase K04715|1|0.0|1016|mmu:223753|ceramide kinase [EC:2.7.1.138] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0001727//lipid kinase activity;GO:0046872//metal ion binding;GO:0008289//lipid binding GO:0006664//glycolipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0016310//phosphorylation;GO:0007186//G-protein coupled receptor signaling pathway gi|62899061|ref|NP_663450.3|/0/ceramide kinase [Mus musculus] 78177 5104 0.22 0.193333333 -0.186413124 Down 0.112405506 Ninl ninein-like K16477|1|0.0|2631|mmu:78177|ninein-like protein - - - gi|568918878|ref|XP_006500469.1|/0/PREDICTED: ninein-like protein isoform X1 [Mus musculus] 56795 1048 2.753333333 2.676666667 -0.040741794 Down 0.11226447 Arl10 ADP-ribosylation factor-like 10 K07958|1|2e-88|328|mmu:56795|ADP-ribosylation factor-like protein 10 GO:0044464 GO:0032550 GO:0035556//intracellular signal transduction gi|564390516|ref|XP_006253691.1|/1.43078e-89/PREDICTED: ADP-ribosylation factor-like protein 10 isoform X1 [Rattus norvegicus] 227449 6024.02 3.006666667 2.93 -0.037264268 Down 0.11226447 Zcchc2 "zinc finger, CCHC domain containing 2" K11722|1|2e-22|111|chx:102188667|bromodomain-containing protein 4 GO:0044424;GO:0044424 GO:0046914//transition metal ion binding;GO:0005543//phospholipid binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0005543//phospholipid binding;GO:0097159//organic cyclic compound binding GO:0044763;GO:0044763 gi|50511081|dbj|BAD32526.1|/0/mKIAA1744 protein [Mus musculus] 547127 4710 2.936666667 2.86 -0.038164371 Down 0.11226447 Tmem181b-ps "transmembrane protein 181B, pseudogene" - - - - - 53858 2104 2.89 2.813333333 -0.038788995 Down 0.11226447 Rwdd2b RWD domain containing 2B - - - - gi|119360352|ref|NP_058620.2|/1.01819e-165/RWD domain-containing protein 2B [Mus musculus] 75678 2934 2.626666667 2.55 -0.042735882 Down 0.11226447 Ippk "inositol 1,3,4,5,6-pentakisphosphate 2-kinase" K10572|1|0.0|1005|mmu:75678|inositol-pentakisphosphate 2-kinase [EC:2.7.1.158] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016301//kinase activity;GO:0032550;GO:0016301//kinase activity;GO:0032550;GO:0016301//kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006020//inositol metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006020//inositol metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0006020//inositol metabolic process "gi|148709131|gb|EDL41077.1|/0/inositol 1,3,4,5,6-pentakisphosphate 2-kinase, isoform CRA_b, partial [Mus musculus]" 13614 2143 2.856666667 2.933333333 0.038208319 Up 0.11226447 Edn1 endothelin 1 K16366|1|8e-78|294|mmu:13614|endothelin-1 GO:0044421;GO:0044424 GO:0031705//bombesin receptor binding GO:0007067//mitotic nuclear division;GO:0019233//sensory perception of pain;GO:0002790//peptide secretion;GO:0045214//sarcomere organization;GO:0014821;GO:0002237//response to molecule of bacterial origin;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0006950//response to stress;GO:0070555//response to interleukin-1;GO:0001501//skeletal system development;GO:0043406//positive regulation of MAP kinase activity;GO:0031324//negative regulation of cellular metabolic process;GO:0060024//rhythmic synaptic transmission;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0046879//hormone secretion;GO:0008284//positive regulation of cell proliferation;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0001990//regulation of systemic arterial blood pressure by hormone;GO:0042044//fluid transport;GO:0043009//chordate embryonic development;GO:0006801//superoxide metabolic process;GO:0014031//mesenchymal cell development;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0006693//prostaglandin metabolic process;GO:0003002//regionalization;GO:0003300//cardiac muscle hypertrophy;GO:0042391//regulation of membrane potential;GO:0006171//cAMP biosynthetic process;GO:0007567//parturition;GO:0048545//response to steroid hormone;GO:0042471//ear morphogenesis;GO:0010558;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008645//hexose transport;GO:0042476//odontogenesis;GO:0002027//regulation of heart rate;GO:0051353//positive regulation of oxidoreductase activity;GO:0040007//growth;GO:0001101//response to acid chemical;GO:0034612//response to tumor necrosis factor;GO:0019932//second-messenger-mediated signaling;GO:0035813//regulation of renal sodium excretion;GO:0014820//tonic smooth muscle contraction;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0008361//regulation of cell size;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0035809;GO:0042310//vasoconstriction "gi|148709037|gb|EDL40983.1|/1.64202e-78/endothelin 1, partial [Mus musculus]" 69930 4190 2.816666667 2.893333333 0.038743701 Up 0.11226447 Zfp715 zinc finger protein 715 K09228|1|0.0|1885|mmu:69930|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - "gi|148690699|gb|EDL22646.1|/0/zinc finger protein 715, isoform CRA_d, partial [Mus musculus]" 74055 9525 3.09 3.006666667 -0.039441905 Down 0.11226447 Plce1 "phospholipase C, epsilon 1" "K05860|1|0.0|4325|mmu:74055|phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]" GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0004629//phospholipase C activity;GO:0030695//GTPase regulator activity;GO:0060089;GO:0046872//metal ion binding;GO:0031267//small GTPase binding GO:0007186//G-protein coupled receptor signaling pathway;GO:0007265//Ras protein signal transduction;GO:0001932//regulation of protein phosphorylation;GO:0006629//lipid metabolic process;GO:0044767//single-organism developmental process "gi|134053943|ref|NP_062534.2|/0/1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 [Mus musculus]" 67306 3361 3.15 3.07 -0.037113173 Down 0.11226447 Zc2hc1a "zinc finger, C2HC-type containing 1A" K00234|1|2e-18|97.8|cfo:105251968|succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1] - GO:0043169//cation binding - gi|27502351|ref|NP_775273.1|/1.76555e-165/zinc finger C2HC domain-containing protein 1A [Mus musculus] 331401 7631 2.75 2.673333333 -0.040791883 Down 0.11226447 Thoc2 THO complex 2 K12879|1|0.0|2694|mmu:331401|THO complex subunit 2 GO:0000346//transcription export complex GO:0003676//nucleic acid binding GO:0006396//RNA processing;GO:0006406//mRNA export from nucleus gi|125656163|ref|NP_001028594.1|/0/THO complex subunit 2 [Mus musculus] 67501 7003.39 3.09 3.166666667 0.035358175 Up 0.11226447 Ccdc50 coiled-coil domain containing 50 - GO:0044424;GO:0044424;GO:0044424 - - gi|71043975|ref|NP_080478.2|/1.44822e-143/coiled-coil domain-containing protein 50 isoform 1 [Mus musculus] 109168 6426.94 3.096666667 3.016666667 -0.037760804 Down 0.11226447 Atl3 atlastin GTPase 3 K17339|1|0.0|1027|mmu:109168|atlastin [EC:3.6.5.-] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0006996//organelle organization;GO:0051259//protein oligomerization;GO:0016482//cytosolic transport;GO:0051259//protein oligomerization;GO:0006996//organelle organization gi|569006247|ref|XP_006526667.1|/0/PREDICTED: atlastin-3 isoform X1 [Mus musculus] 64144 3627 14.48 14.69333333 0.021100121 Up 0.111878973 Mllt1 "myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1" K15187|1|0.0|912|mmu:64144|YEATS domain-containing protein 1/3 GO:0031981//nuclear lumen - GO:0001933//negative regulation of protein phosphorylation "gi|148706265|gb|EDL38212.1|/0/myeloid/lymphoid or mixed lineage-leukemia translocation to 1 homolog (Drosophila), isoform CRA_a, partial [Mus musculus]" 236848 1989 12.78 12.99333333 0.023883754 Up 0.111878973 BC023829 transmembrane protein 185A K00547|1|1e-14|84.3|smm:Smp_147610|homocysteine S-methyltransferase [EC:2.1.1.10] GO:0031224//intrinsic component of membrane - - gi|85701820|ref|NP_001028500.1|/1.61324e-173/transmembrane protein 185A [Mus musculus] 54601 3162 20.05666667 20.26666667 0.015026967 Up 0.111878973 Foxo4 forkhead box O4 K12358|1|0.0|938|mmu:54601|forkhead box protein O4 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0031572//G2 DNA damage checkpoint;GO:0006355//regulation of transcription, DNA-templated;GO:0008283//cell proliferation;GO:0048513//animal organ development;GO:0051318;GO:0030154//cell differentiation;GO:0044767//single-organism developmental process" gi|9055158|ref|NP_061259.1|/0/forkhead box protein O4 [Mus musculus] 72057 1665 17.36 17.15333333 -0.017277991 Down 0.111878973 Phf10 PHD finger protein 10 K11305|1|6e-30|134|tad:TRIADDRAFT_55230|histone acetyltransferase MYST3 [EC:2.3.1.48];K13196|2|5e-29|131|mdo:100017164|zinc finger protein ubi-d4 GO:0090544//BAF-type complex GO:0046914//transition metal ion binding "GO:0048731//system development;GO:0006351//transcription, DNA-templated" gi|341942257|sp|Q9D8M7.4|PHF10_MOUSE/0/RecName: Full=PHD finger protein 10; AltName: Full=BRG1-associated factor 45a; Short=BAF45a 76890 1499 18.64 18.42666667 -0.016606745 Down 0.111878973 Memo1 mediator of cell motility 1 K06990|1|2e-176|621|hgl:101709217|MEMO1 family protein GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle GO:0033218//amide binding GO:0007017//microtubule-based process gi|918608340|ref|XP_013373062.1|/5.73464e-178/PREDICTED: protein MEMO1 [Chinchilla lanigera] 67063 2983 18.39333333 18.18666667 -0.016301812 Down 0.111878973 Tmem246 transmembrane protein 246 K12613|1|1e-14|84.7|bfo:BRAFLDRAFT_98536|mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] GO:0031224//intrinsic component of membrane - - gi|31560202|ref|NP_080220.2|/0/transmembrane protein 246 [Mus musculus] 59001 617 12.68333333 12.47666667 -0.023701405 Down 0.111878973 Pole3 "polymerase (DNA directed), epsilon 3 (p17 subunit)" K02326|1|3e-41|170|pale:102880775|DNA polymerase epsilon subunit 3 [EC:2.7.7.7] GO:0000123//histone acetyltransferase complex;GO:0000109//nucleotide-excision repair complex GO:0003677//DNA binding;GO:0034061//DNA polymerase activity;GO:0046983//protein dimerization activity GO:0006259//DNA metabolic process;GO:0016573//histone acetylation gi|958798036|ref|XP_014683500.1|/1.94484e-40/PREDICTED: DNA polymerase epsilon subunit 3 [Equus asinus] 24132 3079 0.603333333 0.56 -0.107528464 Down 0.111662718 Zfp53 zinc finger protein 53 K09228|1|0.0|1394|mmu:24132|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|7305637|ref|NP_038871.1|/0/zinc finger protein 53 [Mus musculus] 66779 1364 0.543333333 0.503333333 -0.110323415 Down 0.111662718 4933432I09Rik RIKEN cDNA 4933432I09 gene K04954|1|5e-06|55.1|mdo:100012531|hyperpolarization activated cyclic nucleotide-gated potassium channel 1 - - - - 69563 446 0.586666667 0.543333333 -0.110703464 Down 0.111662718 Mrln myoregulin - - - - - 320563 3896 0.53 0.573333333 0.113381799 Up 0.111662718 Islr2 immunoglobulin superfamily containing leucine-rich repeat 2 K16357|1|2e-25|121|bfo:BRAFLDRAFT_84652|leucine-rich repeat and fibronectin type-III domain-containing protein 4;K06838|2|5e-23|113|mze:101467001|slit 1 GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464 - GO:0048731//system development;GO:0030307//positive regulation of cell growth;GO:0048731//system development;GO:0030307//positive regulation of cell growth;GO:0048731//system development;GO:0030307//positive regulation of cell growth;GO:0048731//system development;GO:0030307//positive regulation of cell growth;GO:0048731//system development;GO:0030307//positive regulation of cell growth;GO:0048731//system development;GO:0030307//positive regulation of cell growth;GO:0048731//system development;GO:0030307//positive regulation of cell growth;GO:0048731//system development;GO:0030307//positive regulation of cell growth gi|238859603|ref|NP_001155007.1|/0/immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform a [Mus musculus] 104099 5783.53 14.23333333 14.03 -0.02075856 Down 0.111418256 Itga9 integrin alpha 9 K06585|1|0.0|1984|mmu:104099|integrin alpha 9 - - - gi|74137943|dbj|BAE24106.1|/0/unnamed protein product [Mus musculus] 23790 3436 14.12333333 14.32666667 0.020622354 Up 0.111418256 Coro1c "coronin, actin binding protein 1C" K13886|1|0.0|968|mmu:23790|coronin-1B/1C/6 - - - gi|635067979|ref|XP_008002778.1|/0/PREDICTED: coronin-1C isoform X1 [Chlorocebus sabaeus] 26987 3110.64 16.52666667 16.33 -0.01727098 Down 0.111418256 Eif4e2 eukaryotic translation initiation factor 4E member 2 K03259|1|7e-133|478|acs:100563485|translation initiation factor 4E - - - - 16201 3649.56 13.83666667 13.64 -0.020652787 Down 0.111418256 Ilf3 interleukin enhancer binding factor 3 K13090|1|0.0|1107|rno:84472|interleukin enhancer-binding factor 3 GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding "GO:0008213;GO:0006351//transcription, DNA-templated;GO:0008213;GO:0006351//transcription, DNA-templated;GO:0008213;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0008213;GO:0006351//transcription, DNA-templated;GO:0008213;GO:0006351//transcription, DNA-templated" "gi|148693240|gb|EDL25187.1|/0/interleukin enhancer binding factor 3, isoform CRA_d, partial [Mus musculus]" 109552 2405.21 19.24333333 19.04 -0.015325246 Down 0.111418256 Sri sorcin "K08585|1|7e-28|128|tad:TRIADDRAFT_63582|calpain, invertebrate [EC:3.4.22.-]" GO:0031674//I band;GO:0030667//secretory granule membrane;GO:0005783//endoplasmic reticulum;GO:0031674//I band;GO:0030667//secretory granule membrane;GO:0005783//endoplasmic reticulum GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity GO:0002027//regulation of heart rate;GO:0032970//regulation of actin filament-based process;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0010649//regulation of cell communication by electrical coupling;GO:0090257//regulation of muscle system process;GO:0002027//regulation of heart rate;GO:0032970//regulation of actin filament-based process;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0010649//regulation of cell communication by electrical coupling;GO:0090257//regulation of muscle system process gi|12843188|dbj|BAB25891.1|/9.5118e-94/unnamed protein product [Mus musculus] 20174 1675 17.55 17.74666667 0.01607704 Up 0.111418256 Ruvbl2 RuvB-like protein 2 K11338|1|0.0|877|bacu:103020265|RuvB-like protein 2 [EC:3.6.4.12] GO:0034399//nuclear periphery;GO:0044665//MLL1/2 complex;GO:0043189//H4/H2A histone acetyltransferase complex;GO:0000790//nuclear chromatin GO:0032550;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0004003//ATP-dependent DNA helicase activity "GO:0006351//transcription, DNA-templated;GO:0040007//growth;GO:0009411//response to UV;GO:0009154//purine ribonucleotide catabolic process;GO:0033554//cellular response to stress;GO:0016573//histone acetylation;GO:0032392//DNA geometric change" gi|594629505|ref|XP_007168328.1|/0/PREDICTED: ruvB-like 2 [Balaenoptera acutorostrata scammoni] 30954 782 17.97666667 18.18 0.016226666 Up 0.111418256 Siva1 "SIVA1, apoptosis-inducing factor" - GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0046914//transition metal ion binding;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0004872//receptor activity GO:0012502//induction of programmed cell death;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043029//T cell homeostasis;GO:0043029//T cell homeostasis;GO:0051707//response to other organism;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0012502//induction of programmed cell death gi|240120126|ref|NP_038957.2|/1.08699e-99/apoptosis regulatory protein Siva isoform 1 [Mus musculus] 72716 1644 0.22 0.25 0.184424571 Up 0.111305427 2810047C21Rik1 RIKEN cDNA 2810047C21 gene 1 K09228|1|7e-113|224|mmu:232855|KRAB domain-containing zinc finger protein - - - - 73887 1185 0.26 0.23 -0.176877762 Down 0.111305427 4930417O22Rik RIKEN cDNA 4930417O22 gene - - - - - 100502624 1160 0.2 0.226666667 0.180572246 Up 0.111305427 Gm13483 predicted gene 13483 - - - - gi|148694943|gb|EDL26890.1|/3.20009e-20/mCG1040423 [Mus musculus] 70450 3967 0.233333333 0.206666667 -0.175086707 Down 0.111305427 Unc13d unc-13 homolog D (C. elegans) K19728|1|0.0|2026|mmu:70450|protein unc-13 D GO:0000323//lytic vacuole;GO:0030133//transport vesicle;GO:0005768//endosome GO:0005488//binding GO:0002886;GO:0002323//natural killer cell activation involved in immune response;GO:0006887//exocytosis;GO:0006897//endocytosis;GO:0002460//adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains gi|62243588|ref|NP_001009573.2|/0/protein unc-13 homolog D [Mus musculus] 22414 3573 0.29 0.256666667 -0.176156955 Down 0.111305427 Wnt2b "wingless-type MMTV integration site family, member 2B" "K00182|1|0.0|751|mmu:22414|wingless-type MMTV integration site family, member 2" GO:0005576//extracellular region;GO:0031012//extracellular matrix GO:0005515//protein binding GO:0008283//cell proliferation;GO:0008406//gonad development;GO:0001759//organ induction;GO:0030177//positive regulation of Wnt signaling pathway gi|31543958|ref|NP_033546.2|/0/protein Wnt-2b [Mus musculus] 619715 2163 0.226666667 0.256666667 0.179323699 Up 0.111305427 Gm6093 predicted gene 6093 - - - - - 80718 7217.35 0.28 0.246666667 -0.182864057 Down 0.111305427 Rab27b "RAB27B, member RAS oncogene family" K07886|1|2e-122|444|mmu:80718|Ras-related protein Rab-27B GO:0005771//multivesicular body;GO:0044459;GO:0030667//secretory granule membrane;GO:0005798//Golgi-associated vesicle;GO:0005771//multivesicular body;GO:0044459;GO:0030667//secretory granule membrane;GO:0005798//Golgi-associated vesicle;GO:0005771//multivesicular body;GO:0044459;GO:0030667//secretory granule membrane;GO:0005798//Golgi-associated vesicle;GO:0005771//multivesicular body;GO:0044459;GO:0030667//secretory granule membrane;GO:0005798//Golgi-associated vesicle GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization;GO:0006887//exocytosis "gi|146386539|pdb|2IEZ|A/9.05732e-109/Chain A, Crystal Structure Of Mouse Rab27b Bound To Gdp In Monoclinic Space Group" 104806 7775 0.223333333 0.196666667 -0.183446141 Down 0.111305427 Fancm "Fanconi anemia, complementation group M" K10896|1|0.0|3751|mmu:104806|fanconi anemia group M protein GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0005488//binding GO:0007131//reciprocal meiotic recombination;GO:0006974//cellular response to DNA damage stimulus gi|54112418|ref|NP_849243.2|/0/Fanconi anemia group M protein homolog [Mus musculus] 12393 5707 0.223333333 0.253333333 0.181838323 Up 0.111305427 Runx2 runt related transcription factor 2 K09278|1|1e-171|607|bta:536911|runt-related transcription factor 2 GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0043234//protein complex GO:0032550;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0008134//transcription factor binding;GO:0032550;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0008134//transcription factor binding GO:0002062//chondrocyte differentiation;GO:0001649//osteoblast differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0008283//cell proliferation;GO:0030326//embryonic limb morphogenesis;GO:0021700//developmental maturation;GO:0036075;GO:0007224//smoothened signaling pathway;GO:0042475//odontogenesis of dentin-containing tooth;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030098//lymphocyte differentiation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0048704//embryonic skeletal system morphogenesis;GO:0002062//chondrocyte differentiation;GO:0001649//osteoblast differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0008283//cell proliferation;GO:0030326//embryonic limb morphogenesis;GO:0021700//developmental maturation;GO:0036075;GO:0007224//smoothened signaling pathway;GO:0042475//odontogenesis of dentin-containing tooth;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030098//lymphocyte differentiation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0048704//embryonic skeletal system morphogenesis gi|410110932|ref|NP_001258559.1|/0/runt-related transcription factor 2 isoform 3 [Mus musculus] 19065 1903 0.033333333 0.056666667 0.765534746 Up 0.111296025 Npy4r neuropeptide Y receptor Y4 K04206|1|0.0|743|mmu:19065|neuropeptide Y receptor type 4 GO:0031224//intrinsic component of membrane GO:0033218//amide binding;GO:0004983//neuropeptide Y receptor activity GO:0007267//cell-cell signaling;GO:0007186//G-protein coupled receptor signaling pathway gi|157057097|ref|NP_032945.3|/0/neuropeptide Y receptor type 4 [Mus musculus] 353282 7826 0.04 0.023333333 -0.777607579 Down 0.111296025 Sfmbt2 Scm-like with four mbt domains 2 K11465|1|8e-26|123|pale:102897921|sex comb on midleg-like protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|311771732|ref|NP_001185737.1|/0/scm-like with four MBT domains protein 2 isoform 2 [Mus musculus] 207495 2072 0.053333333 0.03 -0.830074999 Down 0.111296025 Baiap2l2 BAI1-associated protein 2-like 2 K20127|1|0.0|853|mmu:207495|BAI1-associated protein 2-like protein GO:0005911//cell-cell junction;GO:0012505//endomembrane system;GO:0031982//vesicle;GO:0030118//clathrin coat "GO:0030674//protein binding, bridging;GO:0019904//protein domain specific binding" GO:0030031//cell projection assembly;GO:0007154//cell communication gi|29243932|ref|NP_808248.1|/0/brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 [Mus musculus] 76982 3187 0.023333333 0.043333333 0.893084796 Up 0.111296025 3110035E14Rik RIKEN cDNA 3110035E14 gene - - - - gi|30409966|ref|NP_848486.1|/2.44693e-92/uncharacterized protein C8orf46 homolog [Mus musculus] 12686 1879 0.056666667 0.033333333 -0.765534746 Down 0.111296025 Elovl3 "elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3" K10248|1|2e-150|535|mmu:12686|elongation of very long chain fatty acids protein 3 [EC:2.3.1.199] GO:0031224//intrinsic component of membrane GO:0003824//catalytic activity "GO:0019368//fatty acid elongation, unsaturated fatty acid;GO:0000038//very long-chain fatty acid metabolic process" gi|6671752|ref|NP_031729.1|/1.98232e-149/elongation of very long chain fatty acids protein 3 [Mus musculus] 217341 2162 0.05 0.03 -0.736965594 Down 0.111296025 Qrich2 glutamine rich 2 K10421|1|5e-06|55.8|hst:105188449|CAP-Gly domain-containing linker protein 1 - - - gi|755538365|ref|XP_011247261.1|/0/PREDICTED: glutamine-rich protein 2 isoform X7 [Mus musculus] 72169 2830 0.04 0.023333333 -0.777607579 Down 0.111296025 Trim29 tripartite motif-containing 29 K12010|1|0.0|1100|mmu:72169|tripartite motif-containing protein 29 - - - gi|160333881|ref|NP_076144.2|/0/tripartite motif-containing protein 29 [Mus musculus] 209334 3302 0.033333333 0.056666667 0.765534746 Up 0.111296025 Gen1 "GEN1, Holliday junction 5' flap endonuclease" K15338|1|0.0|1830|mmu:209334|flap endonuclease GEN [EC:3.1.-.-] - - - - 271047 2070 0.026666667 0.05 0.906890596 Up 0.111296025 Serpina3b "serine (or cysteine) peptidase inhibitor, clade A, member 3B" "K04525|1|0.0|838|mmu:271047|serpin peptidase inhibitor, clade A" - - - gi|27370538|ref|NP_766612.1|/0/serine protease inhibitor A3B precursor [Mus musculus] 54373 2152 0.03 0.05 0.736965594 Up 0.111296025 Prss16 "protease, serine 16 (thymus)" K09649|1|0.0|922|mmu:54373|thymus-specific serine protease [EC:3.4.-.-] GO:0031982//vesicle;GO:0000323//lytic vacuole "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process gi|9506995|ref|NP_062302.1|/0/thymus-specific serine protease precursor [Mus musculus] 27218 2688 0.04 0.023333333 -0.777607579 Down 0.111296025 Slamf1 signaling lymphocytic activation molecule family member 1 K06536|1|0.0|692|mmu:27218|signaling lymphocytic activation molecule family member 1 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0045321//leukocyte activation gi|29336066|ref|NP_038758.2|/0/signaling lymphocytic activation molecule precursor [Mus musculus] 108105 4548 0.05 0.03 -0.736965594 Down 0.111296025 B3gnt5 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5" "K03766|1|0.0|790|mmu:108105|beta-1,3-N-acetylglucosaminyltransferase 5 [EC:2.4.1.206]" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity GO:0006464//cellular protein modification process;GO:0007399//nervous system development;GO:0006665//sphingolipid metabolic process;GO:0006464//cellular protein modification process;GO:0007399//nervous system development;GO:0006665//sphingolipid metabolic process;GO:0006464//cellular protein modification process;GO:0007399//nervous system development;GO:0006665//sphingolipid metabolic process "gi|31542177|ref|NP_473393.2|/0/lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase [Mus musculus]" 74691 4809 0.023333333 0.043333333 0.893084796 Up 0.111296025 Tdrd9 tudor domain containing 9 K18408|1|0.0|2678|mmu:74691|ATP-dependent RNA helicase TDRD9 [EC:3.6.4.13] - - - gi|171472542|dbj|BAG15992.1|/0/tudor domain containing 9 [Mus musculus] 383563 1960 0.03 0.05 0.736965594 Up 0.111296025 Gpr25 G protein-coupled receptor 25 K08405|1|1e-156|556|mmu:383563|G protein-coupled receptor 25 GO:0016021//integral component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|148707604|gb|EDL39551.1|/8.73728e-156/mCG1047431 [Mus musculus] 268902 8047 0.023333333 0.04 0.777607579 Up 0.111296025 Robo2 roundabout guidance receptor 2 "K06754|1|0.0|2680|mmu:268902|roundabout, axon guidance receptor 2" GO:0031224//intrinsic component of membrane;GO:0032589//neuron projection membrane GO:0004888//transmembrane signaling receptor activity;GO:0046983//protein dimerization activity GO:0035295//tube development;GO:0016337//single organismal cell-cell adhesion;GO:0021889//olfactory bulb interneuron differentiation;GO:0050919//negative chemotaxis;GO:0016198//axon choice point recognition gi|110815826|ref|NP_780758.3|/0/roundabout homolog 2 precursor [Mus musculus] 16870 2234 0.05 0.03 -0.736965594 Down 0.111296025 Lhx2 LIM homeobox protein 2 K09373|1|0.0|671|rno:296706|LIM homeobox protein 2/9 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000989//transcription factor activity, transcription factor binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000989//transcription factor activity, transcription factor binding;GO:0003677//DNA binding" GO:0014020;GO:0006366//transcription from RNA polymerase II promoter;GO:0030900//forebrain development;GO:0043392//negative regulation of DNA binding;GO:0003002//regionalization;GO:0006935//chemotaxis;GO:0030154//cell differentiation;GO:0014020;GO:0006366//transcription from RNA polymerase II promoter;GO:0030900//forebrain development;GO:0043392//negative regulation of DNA binding;GO:0003002//regionalization;GO:0006935//chemotaxis;GO:0030154//cell differentiation gi|537147058|gb|ERE70394.1|/5.80432e-167/LIM/homeobox protein Lhx2-like protein [Cricetulus griseus] 319695 4573 0.026666667 0.046666667 0.807354922 Up 0.111296025 Ankar ankyrin and armadillo repeat containing "K15043|1|3e-10|71.2|mze:101480423|importin subunit alpha-2;K15502|2|5e-09|67.0|hmg:100215811|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A;K10380|3|1e-08|65.9|mde:101900112|ankyrin;K09255|4|1e-08|65.5|hst:105192416|Rel/ankyrin family, other;K10056|5|1e-08|65.5|xla:398496|junction plakoglobin" GO:0031224//intrinsic component of membrane - - gi|258613912|ref|NP_795954.2|/0/ankyrin and armadillo repeat-containing protein [Mus musculus] 99296 2637.01 0.04 0.023333333 -0.777607579 Down 0.111296025 Hrh3 histamine receptor H3 K04151|1|0.0|662|mmu:99296|histamine receptor H3 GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0016021//integral component of membrane;GO:0042995//cell projection GO:0008227//G-protein coupled amine receptor activity;GO:0005488//binding;GO:0008227//G-protein coupled amine receptor activity;GO:0005488//binding GO:0014047//glutamate secretion;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007417//central nervous system development;GO:0007611//learning or memory;GO:0010033//response to organic substance;GO:0048243//norepinephrine secretion;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0008284//positive regulation of cell proliferation;GO:0001505//regulation of neurotransmitter levels;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0007631//feeding behavior;GO:0014051//gamma-aminobutyric acid secretion;GO:0001820//serotonin secretion;GO:0008217//regulation of blood pressure;GO:0014047//glutamate secretion;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007417//central nervous system development;GO:0007611//learning or memory;GO:0010033//response to organic substance;GO:0048243//norepinephrine secretion;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0008284//positive regulation of cell proliferation;GO:0001505//regulation of neurotransmitter levels;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0007631//feeding behavior;GO:0014051//gamma-aminobutyric acid secretion;GO:0001820//serotonin secretion;GO:0008217//regulation of blood pressure gi|194725057|dbj|BAG66249.1|/0/histamine receptor H3 [Mus musculus] 66995 2804 0.023333333 0.04 0.777607579 Up 0.111296025 Zcchc18 "zinc finger, CCHC domain containing 18" - - GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148691941|gb|EDL23888.1|/0/zinc finger, CCHC domain containing 18, isoform CRA_a, partial [Mus musculus]" 329623 2199 0.05 0.026666667 -0.906890596 Down 0.111296025 Gm11548 predicted gene 11548 - - - - "gi|148703129|gb|EDL35076.1|/3.56194e-60/mCG144901, partial [Mus musculus]" 331392 1975 0.03 0.053333333 0.830074999 Up 0.111296025 Gm5124 nucleolar and coiled-body phosphoprotein 1 pseudogene - GO:0016604//nuclear body GO:0005515//protein binding;GO:0030515//snoRNA binding;GO:0005048//signal sequence binding "GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0016074//snoRNA metabolic process;GO:0006997//nucleus organization;GO:0006950//response to stress;GO:0006606//protein import into nucleus" gi|148668397|gb|EDL00721.1|/2.83353e-45/mCG117708 [Mus musculus] 328783 2628 0.04 0.023333333 -0.777607579 Down 0.111296025 Mslnl mesothelin-like K01069|1|7e-31|138|mgp:100548105|hydroxyacylglutathione hydrolase [EC:3.1.2.6] GO:0031224//intrinsic component of membrane - GO:0022610 "gi|148690496|gb|EDL22443.1|/0/cDNA sequence BC052484, isoform CRA_b, partial [Mus musculus]" 80334 2188 0.05 0.03 -0.736965594 Down 0.111296025 Kcnip4 Kv channel interacting protein 4 K16575|1|3e-85|318|aam:106493806|centractin;K19932|2|1e-43|181|cin:100183109|neuronal calcium sensor 1 GO:0043005//neuron projection;GO:0044297//cell body;GO:0016020//membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0016020//membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0016020//membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0016020//membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0016020//membrane GO:0046872//metal ion binding;GO:0005261//cation channel activity;GO:0046872//metal ion binding;GO:0005261//cation channel activity;GO:0046872//metal ion binding;GO:0005261//cation channel activity;GO:0046872//metal ion binding;GO:0005261//cation channel activity;GO:0046872//metal ion binding;GO:0005261//cation channel activity GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|31077142|ref|NP_852030.1|/4.19771e-139/Kv channel-interacting protein 4 [Rattus norvegicus] 57775 7476 0.03 0.05 0.736965594 Up 0.111296025 Usp29 ubiquitin specific peptidase 29 K11850|1|0.0|1628|mmu:57775|ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12] - "GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019941//modification-dependent protein catabolic process gi|755519943|ref|XP_011248964.1|/0/PREDICTED: ubiquitin carboxyl-terminal hydrolase 29 isoform X1 [Mus musculus] 70417 7514 0.026666667 0.05 0.906890596 Up 0.111296025 Megf10 multiple EGF-like-domains 10 K02258|1|3e-155|553|hmg:100209451|cytochrome c oxidase assembly protein subunit 11 GO:0031224//intrinsic component of membrane;GO:0044459 - "GO:0006910//phagocytosis, recognition;GO:0016337//single organismal cell-cell adhesion;GO:0001775//cell activation;GO:0042692//muscle cell differentiation;GO:0007519//skeletal muscle tissue development;GO:0008283//cell proliferation" gi|50233828|ref|NP_001001979.1|/0/multiple epidermal growth factor-like domains protein 10 precursor [Mus musculus] 18163 5959 0.02 0.036666667 0.874469118 Up 0.111296025 Ctnnd2 "catenin (cadherin associated protein), delta 2" "K05690|1|3e-118|430|amj:102573160|catenin (cadherin-associated protein), delta 1" GO:0043231//intracellular membrane-bounded organelle;GO:0044327//dendritic spine head - "GO:0022610;GO:0050804//modulation of synaptic transmission;GO:0007611//learning or memory;GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|112363090|ref|NP_032755.2|/0/catenin delta-2 [Mus musculus] 94222 2086 0.053333333 0.03 -0.830074999 Down 0.111296025 Olig3 oligodendrocyte transcription factor 3 K09085|1|2e-112|409|rno:293012|class B basic helix-loop-helix protein 1/6/7 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0005515//protein binding "GO:0006351//transcription, DNA-templated" gi|157820277|ref|NP_001099739.1|/1.43091e-111/oligodendrocyte transcription factor 3 [Rattus norvegicus] 626359 2285 0.05 0.026666667 -0.906890596 Down 0.111296025 Wdr93 WD repeat domain 93 - - - - gi|83776569|ref|NP_001033016.1|/0/WD repeat-containing protein 93 [Mus musculus] 13909 1915 0.033333333 0.056666667 0.765534746 Up 0.111296025 Ces3b carboxylesterase 3B K15743|1|0.0|1003|mmu:13909|carboxylesterase 3/5 [EC:3.1.1.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0052689//carboxylic ester hydrolase activity;GO:0052689//carboxylic ester hydrolase activity - gi|226874914|ref|NP_653094.2|/0/carboxylesterase 3B isoform 1 precursor [Mus musculus] 105120 4106.06 0.03 0.05 0.736965594 Up 0.111296025 AI197445 expressed sequence AI197445 - - - - - 225152 2661 0.043333333 0.023333333 -0.893084796 Down 0.111296025 Gjd4 "gap junction protein, delta 4" K07630|1|2e-168|595|mmu:225152|Gap junction delta-4 protein - - - - 217682 3527 0.023333333 0.04 0.777607579 Up 0.111296025 Plekhd1 "pleckstrin homology domain containing, family D (with coiled-coil domains) member 1" - - GO:0008289//lipid binding - gi|294610655|ref|NP_001170974.1|/0/pleckstrin homology domain-containing family D member 1 [Mus musculus] 100038460 2102 0.053333333 0.03 -0.830074999 Down 0.111296025 Gm10677 predicted gene 10677 K06781|1|6e-23|112|pale:102880418|cell adhesion molecule 1 - - - gi|74193441|dbj|BAE20665.1|/5.41437e-42/unnamed protein product [Mus musculus] 233231 4185 0.023333333 0.043333333 0.893084796 Up 0.111296025 Mrgprb1 "MAS-related GPR, member B1" K08396|1|3e-134|483|mmu:243978|Mas-related G protein-coupled receptor member X GO:0031224//intrinsic component of membrane GO:0042277//peptide binding;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|154240718|ref|NP_991379.3|/0/mas-related G-protein coupled receptor member B1 [Mus musculus] 100502861 2656 0.043333333 0.023333333 -0.893084796 Down 0.111296025 Ccdc13 coiled-coil domain containing 13 K10352|1|1e-13|81.3|mze:101475480|myosin heavy chain - - - gi|304555596|ref|NP_082660.1|/0/coiled-coil domain-containing protein 13 [Mus musculus] 16398 4235 0.04 0.023333333 -0.777607579 Down 0.111296025 Itga2 integrin alpha 2 K06481|1|0.0|2219|mmu:16398|integrin alpha 2 GO:0009986//cell surface;GO:0033267;GO:0019867//outer membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0044444//cytoplasmic part;GO:0005924//cell-substrate adherens junction GO:0005102//receptor binding;GO:0043169//cation binding;GO:0046983//protein dimerization activity "GO:0006954//inflammatory response;GO:0050918//positive chemotaxis;GO:0008284//positive regulation of cell proliferation;GO:0032092//positive regulation of protein binding;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010647//positive regulation of cell communication;GO:0043588//skin development;GO:0008104//protein localization;GO:0006911//phagocytosis, engulfment;GO:0019233//sensory perception of pain;GO:0006970//response to osmotic stress;GO:0002684//positive regulation of immune system process;GO:0010692;GO:0007166//cell surface receptor signaling pathway;GO:0006939//smooth muscle contraction;GO:0007155//cell adhesion;GO:0010631//epithelial cell migration;GO:0014909//smooth muscle cell migration;GO:0006412//translation;GO:0030030//cell projection organization" gi|473099|emb|CAA82877.1|/0/VLA-2 homologue [Mus musculus] 330406 2961 0.036666667 0.02 -0.874469118 Down 0.111296025 B4galnt3 "beta-1,4-N-acetyl-galactosaminyl transferase 3" "K09656|1|0.0|1925|mmu:330406|beta-1,4-N-acetylgalactosaminyltransferase 3 [EC:2.4.1.244]" GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane GO:0008376//acetylgalactosaminyltransferase activity - "gi|38566700|ref|NP_942585.1|/0/beta-1,4-N-acetylgalactosaminyltransferase 3 [Mus musculus]" 239731 5848 0.02 0.036666667 0.874469118 Up 0.111296025 Rimbp3 RIMS binding protein 3 K19922|1|8e-119|432|phd:102318292|peripheral-type benzodiazepine receptor-associated protein 1 GO:0043231//intracellular membrane-bounded organelle - - gi|191252808|ref|NP_001028510.2|/0/RIMS-binding protein 3 [Mus musculus] 75323 2052 0.053333333 0.03 -0.830074999 Down 0.111296025 4930558J18Rik RIKEN cDNA 4930558J18 gene - - - - "gi|148667630|gb|EDL00047.1|/7.59471e-33/mCG1035637, partial [Mus musculus]" 12167 5183 0.023333333 0.043333333 0.893084796 Up 0.111296025 Bmpr1b "bone morphogenetic protein receptor, type 1B" K13578|1|0.0|1014|ocu:100351275|bone morphogenetic protein receptor type-1B [EC:2.7.11.30] GO:0043005//neuron projection;GO:0044297//cell body;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0031224//intrinsic component of membrane GO:0032550;GO:0005515//protein binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0043169//cation binding;GO:0032550;GO:0005515//protein binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0043169//cation binding;GO:0032550;GO:0005515//protein binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0043169//cation binding;GO:0032550;GO:0005515//protein binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0043169//cation binding;GO:0032550;GO:0005515//protein binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0043169//cation binding GO:0001501//skeletal system development;GO:0007411//axon guidance;GO:0035107//appendage morphogenesis;GO:0001649//osteoblast differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043010//camera-type eye development;GO:0006694//steroid biosynthetic process;GO:0016337//single organismal cell-cell adhesion;GO:0001547//antral ovarian follicle growth;GO:0006796//phosphate-containing compound metabolic process;GO:0003002//regionalization;GO:0030282//bone mineralization;GO:0006464//cellular protein modification process;GO:0006952//defense response;GO:0001501//skeletal system development;GO:0007411//axon guidance;GO:0035107//appendage morphogenesis;GO:0001649//osteoblast differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043010//camera-type eye development;GO:0006694//steroid biosynthetic process;GO:0016337//single organismal cell-cell adhesion;GO:0001547//antral ovarian follicle growth;GO:0006796//phosphate-containing compound metabolic process;GO:0003002//regionalization;GO:0030282//bone mineralization;GO:0006464//cellular protein modification process;GO:0006952//defense response;GO:0001501//skeletal system development;GO:0007411//axon guidance;GO:0035107//appendage morphogenesis;GO:0001649//osteoblast differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043010//camera-type eye development;GO:0006694//steroid biosynthetic process;GO:0016337//single organismal cell-cell adhesion;GO:0001547//antral ovarian follicle growth;GO:0006796//phosphate-containing compound metabolic process;GO:0003002//regionalization;GO:0030282//bone mineralization;GO:0006464//cellular protein modification process;GO:0006952//defense response;GO:0001501//skeletal system development;GO:0007411//axon guidance;GO:0035107//appendage morphogenesis;GO:0001649//osteoblast differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043010//camera-type eye development;GO:0006694//steroid biosynthetic process;GO:0016337//single organismal cell-cell adhesion;GO:0001547//antral ovarian follicle growth;GO:0006796//phosphate-containing compound metabolic process;GO:0003002//regionalization;GO:0030282//bone mineralization;GO:0006464//cellular protein modification process;GO:0006952//defense response;GO:0001501//skeletal system development;GO:0007411//axon guidance;GO:0035107//appendage morphogenesis;GO:0001649//osteoblast differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043010//camera-type eye development;GO:0006694//steroid biosynthetic process;GO:0016337//single organismal cell-cell adhesion;GO:0001547//antral ovarian follicle growth;GO:0006796//phosphate-containing compound metabolic process;GO:0003002//regionalization;GO:0030282//bone mineralization;GO:0006464//cellular protein modification process;GO:0006952//defense response gi|537271995|gb|ERE92093.1|/0/bone morphogenetic protein receptor type-1B [Cricetulus griseus] 227357 5442 0.04 0.023333333 -0.777607579 Down 0.111296025 Espnl espin-like K18441|1|7e-34|149|aqu:100641148|cytohesin - - - gi|85701794|ref|NP_001028464.1|/0/espin-like protein [Mus musculus] 210045 3274 0.02 0.036666667 0.874469118 Up 0.111296025 Nlrp4b "NLR family, pyrin domain containing 4B" "K19409|1|3e-105|386|bom:102272683|NACHT, LRR and PYD domains-containing protein 2/7" - GO:0032550 GO:0006950//response to stress "gi|27369660|ref|NP_766069.1|/0/NACHT, LRR and PYD domains-containing protein 4B [Mus musculus]" 242891 1967 0.033333333 0.056666667 0.765534746 Up 0.111296025 Cct8l1 "chaperonin containing TCP1, subunit 8 (theta)-like 1" K09500|1|2e-72|276|amj:102574263|T-complex protein 1 subunit theta GO:0044424 GO:0005515//protein binding;GO:0032550 GO:0044267//cellular protein metabolic process "gi|29747973|gb|AAH50797.1|/0/Gene model 443, (NCBI) [Mus musculus] " 23968 3304 0.02 0.036666667 0.874469118 Up 0.111296025 Nlrp5 "NLR family, pyrin domain containing 5" "K19409|1|1e-135|486|ecb:100055187|NACHT, LRR and PYD domains-containing protein 2/7" GO:0032991//macromolecular complex;GO:0044448;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0044448;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0044448;GO:0031981//nuclear lumen GO:0032550;GO:0032550;GO:0032550 GO:0010608//posttranscriptional regulation of gene expression;GO:0043009//chordate embryonic development;GO:0006461//protein complex assembly;GO:0019953//sexual reproduction;GO:0009653//anatomical structure morphogenesis;GO:0010608//posttranscriptional regulation of gene expression;GO:0043009//chordate embryonic development;GO:0006461//protein complex assembly;GO:0019953//sexual reproduction;GO:0009653//anatomical structure morphogenesis;GO:0010608//posttranscriptional regulation of gene expression;GO:0043009//chordate embryonic development;GO:0006461//protein complex assembly;GO:0019953//sexual reproduction;GO:0009653//anatomical structure morphogenesis "gi|803378417|ref|NP_001292786.1|/0/NACHT, LRR and PYD domains-containing protein 5 isoform c [Mus musculus]" 434797 2861 0.023333333 0.04 0.777607579 Up 0.111296025 Gm5640 predicted gene 5640 - - - - gi|150010625|ref|NP_001092772.1|/0/melanoma associated antigen (mutated) 1-like [Mus musculus] 17167 1985 0.033333333 0.056666667 0.765534746 Up 0.111296025 Marco macrophage receptor with collagenous structure K13884|1|0.0|739|mmu:17167|macrophage receptor with collagenous structure GO:0031224//intrinsic component of membrane GO:0004872//receptor activity GO:0006952//defense response;GO:0006909//phagocytosis gi|6754640|ref|NP_034896.1|/0/macrophage receptor MARCO [Mus musculus] 14417 5625 0.94 0.893333333 -0.073462162 Down 0.111098575 Gad2 glutamic acid decarboxylase 2 K01580|1|0.0|1176|mmu:14417|glutamate decarboxylase [EC:4.1.1.15] GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0008021//synaptic vesicle;GO:0097060//synaptic membrane GO:0046983//protein dimerization activity;GO:0016597//amino acid binding;GO:0016831//carboxy-lyase activity GO:0006105//succinate metabolic process;GO:0042133//neurotransmitter metabolic process;GO:0042221//response to chemical gi|124517709|ref|NP_032104.2|/0/glutamate decarboxylase 2 [Mus musculus] 20660 6938 0.976666667 1.023333333 0.067337991 Up 0.111098575 Sorl1 "sortilin-related receptor, LDLR class A repeats-containing" K04550|1|1e-133|481|cjo:107325839|low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor) GO:0034358//plasma lipoprotein particle;GO:0016021//integral component of membrane;GO:0044297//cell body GO:0071813//lipoprotein particle binding;GO:0038023//signaling receptor activity GO:0048870//cell motility;GO:0016125//sterol metabolic process;GO:0006897//endocytosis gi|110625645|ref|NP_035566.2|/0/sortilin-related receptor precursor [Mus musculus] 71544 5404 1.06 1.113333333 0.070821337 Up 0.111098575 Arhgap42 Rho GTPase activating protein 42 K20071|1|1e-177|627|mze:101480767|Rho GTPase-activating protein 26 GO:0044464 "GO:0030674//protein binding, bridging;GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0019904//protein domain specific binding" GO:0043087//regulation of GTPase activity;GO:0007154//cell communication;GO:0030031//cell projection assembly gi|198278482|ref|NP_082099.1|/0/rho GTPase-activating protein 42 [Mus musculus] 241075 8562 1.006666667 0.96 -0.068479738 Down 0.111098575 Plekhm3 "pleckstrin homology domain containing, family M, member 3" K19330|1|3e-41|174|ame:413668|run domain Beclin-1 interacting and cysteine-rich containing protein - GO:0008289//lipid binding;GO:0043169//cation binding GO:0007165//signal transduction "gi|148667794|gb|EDL00211.1|/0/mCG123132, isoform CRA_b, partial [Mus musculus]" 78506 3268 1.146666667 1.093333333 -0.06871275 Down 0.111098575 Micu3 "mitochondrial calcium uptake family, member 3" K20028|1|6e-43|179|oaa:100078401|palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225] - - - "gi|255003807|ref|NP_084386.1|/0/calcium uptake protein 3, mitochondrial [Mus musculus]" 227746 1858 5.733333333 5.836666667 0.025770519 Up 0.111070367 Rabepk Rab9 effector protein with kelch motifs K20285|1|0.0|763|mmu:227746|Rab9 effector protein with kelch motifs GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|31559945|ref|NP_663497.2|/0/rab9 effector protein with kelch motifs [Mus musculus] 227731 3195 5.376666667 5.273333333 -0.027996839 Down 0.111070367 Slc25a25 "solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25" "K14684|1|0.0|999|hgl:101712492|solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41" GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding;GO:0043169//cation binding;GO:0043169//cation binding;GO:0043169//cation binding GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763 gi|594542563|ref|NP_001277487.1|/0/calcium-binding mitochondrial carrier protein SCaMC-2 isoform 4 [Mus musculus] 217370 2429.63 4.42 4.52 0.032276403 Up 0.111070367 BC017643 cDNA sequence BC017643 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|361050365|ref|NP_001241664.1|/1.98221e-101/uncharacterized protein C17orf62 homolog isoform 3 [Mus musculus] 57247 4877 4.473333333 4.573333333 0.03189581 Up 0.111070367 Zfp276 zinc finger protein (C2H2 type) 276 K10888|1|7e-36|156|mmu:14087|fanconi anemia group A protein;K04961|4|3e-33|147|ocu:103351584|ryanodine receptor 1 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding - gi|165377130|ref|NP_065243.2|/0/zinc finger protein 276 [Mus musculus] 74108 2902 5.42 5.516666667 0.02550396 Up 0.111070367 Parn poly(A)-specific ribonuclease (deadenylation nuclease) K01148|1|0.0|1097|mmu:74108|poly(A)-specific ribonuclease [EC:3.1.13.4] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0019900//kinase binding;GO:0000175//3'-5'-exoribonuclease activity "GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" "gi|148664948|gb|EDK97364.1|/0/poly(A)-specific ribonuclease (deadenylation nuclease), isoform CRA_c, partial [Mus musculus]" 235626 8350 4.786666667 4.886666667 0.029829354 Up 0.111070367 Setd2 SET domain containing 2 K11423|1|0.0|4454|mmu:235626|histone-lysine N-methyltransferase SETD2 [EC:2.1.1.43] - - - gi|197927225|ref|NP_001074809.2|/0/histone-lysine N-methyltransferase SETD2 [Mus musculus] 98386 3568 5.43 5.533333333 0.027196638 Up 0.111070367 Lbr lamin B receptor K19532|1|0.0|1064|mmu:98386|lamin-B receptor GO:0019866//organelle inner membrane;GO:0005635//nuclear envelope;GO:0031224//intrinsic component of membrane;GO:0034399//nuclear periphery "GO:0019904//protein domain specific binding;GO:0003676//nucleic acid binding;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors" GO:0044710 "gi|148681171|gb|EDL13118.1|/0/lamin B receptor, partial [Mus musculus]" 245847 1463 5.403333333 5.306666667 -0.026043755 Down 0.111070367 Amdhd2 amidohydrolase domain containing 2 K01443|1|0.0|825|mmu:245847|N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25] - "GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0043169//cation binding" GO:1901071;GO:0006054//N-acetylneuraminate metabolic process;GO:0044238//primary metabolic process gi|22477714|gb|AAH37005.1|/0/Amidohydrolase domain containing 2 [Mus musculus] 66691 5966 4.503333333 4.403333333 -0.032397208 Down 0.111070367 Gapvd1 GTPase activating protein and VPS9 domains 1 K20131|1|7e-19|100|tru:101073601|Rab5 GDP/GTP exchange factor GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0008047//enzyme activator activity;GO:0005515//protein binding;GO:0030695//GTPase regulator activity GO:0019222//regulation of metabolic process;GO:0016192//vesicle-mediated transport;GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport gi|40254514|ref|NP_079985.2|/0/GTPase-activating protein and VPS9 domain-containing protein 1 [Mus musculus] 12695 6050.92 5.44 5.343333333 -0.025866632 Down 0.111070367 Inadl InaD-like (Drosophila) K06092|1|0.0|3456|mmu:12695|InaD-like protein GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part;GO:0043296//apical junction complex;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part;GO:0043296//apical junction complex;GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part;GO:0043296//apical junction complex;GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part;GO:0043296//apical junction complex - - gi|55769578|ref|NP_766284.2|/0/inaD-like protein isoform 1 [Mus musculus] 11536 1694 4.516666667 4.416666667 -0.032300492 Down 0.111070367 Gpr182 G protein-coupled receptor 182 K04242|1|0.0|762|mmu:11536|adrenomedullin receptor GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0006950//response to stress gi|117606339|ref|NP_031438.2|/0/G-protein coupled receptor 182 [Mus musculus] 20947 4056 4.276666667 4.18 -0.032983822 Down 0.111070367 Swap70 SWA-70 protein K20072|1|0.0|985|mmu:20947|switch-associated protein 70 GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0032550;GO:0008289//lipid binding GO:0002204//somatic recombination of immunoglobulin genes involved in immune response gi|50510565|dbj|BAD32268.1|/0/mKIAA0640 protein [Mus musculus] 328370 2384 4.626666667 4.723333333 0.02983219 Up 0.111070367 Rft1 RFT1 homolog K06316|1|0.0|994|mmu:328370|oligosaccharide translocation protein RFT1 GO:0031224//intrinsic component of membrane GO:0022892//substrate-specific transporter activity GO:0010876//lipid localization;GO:0044765//single-organism transport;GO:0006487//protein N-linked glycosylation gi|87299621|ref|NP_808483.2|/0/protein RFT1 homolog [Mus musculus] 74450 4266 5.85 5.746666667 -0.025711256 Down 0.111070367 Pank2 pantothenate kinase 2 K09680|1|0.0|709|mmu:74450|type II pantothenate kinase [EC:2.7.1.33] GO:0043231//intracellular membrane-bounded organelle "GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006796//phosphate-containing compound metabolic process "gi|148696370|gb|EDL28317.1|/0/pantothenate kinase 2 (Hallervorden-Spatz syndrome), isoform CRA_a, partial [Mus musculus]" 216742 6281 5.463333333 5.566666667 0.027032248 Up 0.111070367 Fnip1 folliculin interacting protein 1 K20400|1|0.0|2253|mmu:216742|folliculin-interacting protein 1 - - - - 234138 2772.86 5.146666667 5.046666667 -0.028307547 Down 0.111070367 Tti2 TELO2 interacting protein 2 K11585|1|4e-21|107|phu:Phum_PHUM259320|chromobox protein 1;K06704|2|4e-14|84.0|aqu:100638224|disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81] - - - gi|316983174|ref|NP_001186917.1|/0/TELO2-interacting protein 2 isoform b [Mus musculus] 224143 2915.36 4.556666667 4.456666667 -0.032013778 Down 0.111070367 Poglut1 protein O-glucosyltransferase 1 K13667|1|0.0|819|mmu:224143|protein glucosyltransferase [EC:2.4.1.-] GO:0044432;GO:0044432 "GO:0016758//transferase activity, transferring hexosyl groups;GO:0008194//UDP-glycosyltransferase activity;GO:0016758//transferase activity, transferring hexosyl groups;GO:0008194//UDP-glycosyltransferase activity" GO:0048731//system development;GO:0007219//Notch signaling pathway;GO:0006486//protein glycosylation;GO:0048731//system development;GO:0007219//Notch signaling pathway;GO:0006486//protein glycosylation gi|27369505|ref|NP_759012.1|/0/protein O-glucosyltransferase 1 isoform 1 precursor [Mus musculus] 232811 2239.67 5.836666667 5.94 0.025318253 Up 0.111070367 Suv420h2 suppressor of variegation 4-20 homolog 2 (Drosophila) K11429|1|0.0|849|mmu:232811|histone-lysine N-methyltransferase SUV420H [EC:2.1.1.43] GO:0000794//condensed nuclear chromosome;GO:0000794//condensed nuclear chromosome GO:0018024//histone-lysine N-methyltransferase activity;GO:0018024//histone-lysine N-methyltransferase activity "GO:0034968//histone lysine methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0006351//transcription, DNA-templated;GO:0034968//histone lysine methylation;GO:0018023//peptidyl-lysine trimethylation;GO:0006351//transcription, DNA-templated" gi|169234795|ref|NP_666289.2|/0/histone-lysine N-methyltransferase SUV420H2 [Mus musculus] 232430 2536 5.003333333 5.106666667 0.02949232 Up 0.111070367 Crebl2 cAMP responsive element binding protein-like 2 - GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0001934//positive regulation of protein phosphorylation;GO:0006351//transcription, DNA-templated;GO:0031647//regulation of protein stability;GO:0008610//lipid biosynthetic process;GO:0045444//fat cell differentiation;GO:0010828//positive regulation of glucose transport" gi|755516639|ref|XP_011239626.1|/3.96393e-76/PREDICTED: cAMP-responsive element-binding protein-like 2 isoform X1 [Mus musculus] 216033 3622.34 5.616666667 5.72 0.026300961 Up 0.111070367 Ctnna3 "catenin (cadherin associated protein), alpha 3" K05691|1|0.0|1588|mmu:216033|catenin alpha GO:0005856//cytoskeleton;GO:0031252//cell leading edge;GO:0005913//cell-cell adherens junction;GO:0005856//cytoskeleton;GO:0031252//cell leading edge;GO:0005913//cell-cell adherens junction;GO:0005856//cytoskeleton;GO:0031252//cell leading edge;GO:0005913//cell-cell adherens junction GO:0050839//cell adhesion molecule binding;GO:0050839//cell adhesion molecule binding;GO:0050839//cell adhesion molecule binding GO:0007155//cell adhesion;GO:0007155//cell adhesion;GO:0007155//cell adhesion gi|256985152|ref|NP_001157991.1|/0/catenin alpha-3 isoform 2 [Mus musculus] 78394 3180 4.09 4.19 0.034849401 Up 0.111070367 Ddx52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 K14779|1|0.0|1068|mmu:78394|ATP-dependent RNA helicase DDX52/ROK1 [EC:3.6.4.13] GO:0031981//nuclear lumen "GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0004386//helicase activity" GO:0042254//ribosome biogenesis gi|74177868|dbj|BAE39019.1|/0/unnamed protein product [Mus musculus] 19255 2040.09 5.313333333 5.416666667 0.027788089 Up 0.111070367 Ptpn2 "protein tyrosine phosphatase, non-receptor type 2" K18026|1|0.0|769|mmu:19255|tyrosine-protein phosphatase non-receptor type 2 [EC:3.1.3.48] GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen GO:0004725//protein tyrosine phosphatase activity;GO:0005488//binding;GO:0004725//protein tyrosine phosphatase activity GO:0006464//cellular protein modification process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0006470//protein dephosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001959//regulation of cytokine-mediated signaling pathway gi|187608416|ref|NP_001120649.1|/0/tyrosine-protein phosphatase non-receptor type 2 isoform b [Mus musculus] 224139 11025 4.84 4.74 -0.030119988 Down 0.111070367 Golgb1 "golgi autoantigen, golgin subfamily b, macrogolgin 1" K20478|1|0.0|5278|mmu:224139|golgin subfamily B member 1 GO:0043231//intracellular membrane-bounded organelle - - gi|226958601|ref|NP_084311.1|/0/golgin subfamily B member 1 [Mus musculus] 213541 4078 5.776666667 5.676666667 -0.025193219 Down 0.111070367 Ythdf2 YTH domain family 2 K20102|1|0.0|1053|mmu:213541|YTH domain-containing family protein - - GO:0006955//immune response gi|225543110|ref|NP_663368.3|/0/YTH domain-containing family protein 2 [Mus musculus] 20588 5684 5.52 5.616666667 0.025045919 Up 0.111070367 Smarcc1 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1" K11649|1|0.0|1677|mmu:20588|SWI/SNF related-matrix-associated actin-dependent regulator of chromatin subfamily C GO:0031981//nuclear lumen;GO:0090544//BAF-type complex GO:0005515//protein binding;GO:0003676//nucleic acid binding GO:0009653//anatomical structure morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0034728//nucleosome organization;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016568//chromatin modification "gi|148677078|gb|EDL09025.1|/0/SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1, isoform CRA_b, partial [Mus musculus]" 18706 8917 3.94 4.036666667 0.03496883 Up 0.111070367 Pik3ca "phosphatidylinositol 3-kinase, catalytic, alpha polypeptide" "K00922|1|0.0|2200|mmu:18706|phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]" GO:0005942//phosphatidylinositol 3-kinase complex;GO:0031252//cell leading edge GO:0032550;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0019887//protein kinase regulator activity;GO:0052742 GO:0001934//positive regulation of protein phosphorylation;GO:0044028;GO:0043066//negative regulation of apoptotic process;GO:0048017//inositol lipid-mediated signaling;GO:0019318//hexose metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0035264//multicellular organism growth "gi|365813404|pdb|4A55|A/0/Chain A, Crystal Structure Of P110alpha In Complex With Ish2 Of P85alpha And The Inhibitor Pik-108" 230073 4943 4.19 4.29 0.034027404 Up 0.111070367 Ddx58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 K12646|1|0.0|1782|mmu:230073|ATP-dependent RNA helicase DDX58 [EC:3.6.3.14] GO:0016020//membrane;GO:0043296//apical junction complex;GO:0001726//ruffle;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part "GO:0046914//transition metal ion binding;GO:0032550;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0042623//ATPase activity, coupled;GO:0043566//structure-specific DNA binding" GO:0032481//positive regulation of type I interferon production;GO:0006366//transcription from RNA polymerase II promoter;GO:0001818//negative regulation of cytokine production;GO:0050691//regulation of defense response to virus by host;GO:0039528//cytoplasmic pattern recognition receptor signaling pathway in response to virus;GO:0044093;GO:0043331//response to dsRNA;GO:0016477//cell migration;GO:0042307//positive regulation of protein import into nucleus gi|153945886|ref|NP_766277.3|/0/probable ATP-dependent RNA helicase DDX58 [Mus musculus] 98752 1658 0.036666667 0.06 0.710493383 Up 0.110929332 Fcrla Fc receptor-like A K17273|1|3e-39|165|ggo:101142925|Fc receptor-like protein 6;K06498|4|6e-38|161|umr:103667577|high affinity immunoglobulin gamma Fc receptor I GO:0044424;GO:0044424;GO:0044424 - GO:0048869//cellular developmental process;GO:0048869//cellular developmental process;GO:0048869//cellular developmental process gi|237649052|ref|NP_001153687.1|/1.22065e-166/Fc receptor-like A isoform 1 precursor [Mus musculus] 18419 10043 0.033333333 0.05 0.584962501 Up 0.110929332 Otog otogelin K03900|1|0.0|650|ptg:102965421|von Willebrand factor GO:0031012//extracellular matrix;GO:0044444//cytoplasmic part;GO:0016020//membrane "GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds" GO:0007599//hemostasis;GO:0019566//arabinose metabolic process;GO:0050954//sensory perception of mechanical stimulus;GO:0022610;GO:0007626//locomotory behavior gi|190358487|ref|NP_038652.2|/0/otogelin precursor [Mus musculus] 100504265 5940 0.036666667 0.06 0.710493383 Up 0.110929332 Gm20139 "predicted gene, 20139" - - - - "gi|148671508|gb|EDL03455.1|/3.68874e-42/mCG144972, partial [Mus musculus]" 545975 3251 0.033333333 0.053333333 0.678071905 Up 0.110929332 Cers3 ceramide synthase 3 K04710|1|0.0|806|mmu:545975|ceramide synthetase [EC:2.3.1.24] - - - - 26459 2336 0.026666667 0.043333333 0.700439718 Up 0.110929332 Slc27a5 "solute carrier family 27 (fatty acid transporter), member 5" "K08748|1|0.0|1311|mmu:26459|solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7]" GO:0032991//macromolecular complex;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0016323//basolateral plasma membrane GO:0032550;GO:0015645//fatty acid ligase activity;GO:0016878//acid-thiol ligase activity;GO:0005515//protein binding;GO:0005319//lipid transporter activity GO:0044249//cellular biosynthetic process;GO:0006631//fatty acid metabolic process;GO:0006641//triglyceride metabolic process;GO:0006694//steroid biosynthetic process;GO:0015909//long-chain fatty acid transport gi|228008365|ref|NP_033538.2|/0/bile acyl-CoA synthetase precursor [Mus musculus] 14812 7515 0.06 0.04 -0.584962501 Down 0.110929332 Grin2b "glutamate receptor, ionotropic, NMDA2B (epsilon 2)" "K05210|1|0.0|2939|mmu:14812|glutamate receptor ionotropic, NMDA 2B" GO:0033267;GO:0044420//extracellular matrix component;GO:0008328//ionotropic glutamate receptor complex;GO:0044327//dendritic spine head;GO:0030136//clathrin-coated vesicle;GO:0030313//cell envelope;GO:0031674//I band;GO:0097060//synaptic membrane GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0005261//cation channel activity;GO:0004970//ionotropic glutamate receptor activity;GO:0005126//cytokine receptor binding;GO:0050780//dopamine receptor binding;GO:0035254//glutamate receptor binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0016597//amino acid binding GO:0009636//response to toxic substance;GO:0033555//multicellular organismal response to stress;GO:0009628//response to abiotic stimulus;GO:0043434//response to peptide hormone;GO:0007631//feeding behavior;GO:0009607//response to biotic stimulus;GO:0014075//response to amine;GO:0007215//glutamate receptor signaling pathway;GO:0043009//chordate embryonic development;GO:0051899//membrane depolarization;GO:0002209//behavioral defense response;GO:0021543//pallium development;GO:0007613//memory;GO:0019233//sensory perception of pain;GO:0072657//protein localization to membrane;GO:0043331//response to dsRNA;GO:0043200//response to amino acid;GO:0033993//response to lipid;GO:0014047//glutamate secretion;GO:0007612//learning;GO:0010042//response to manganese ion;GO:0070848//response to growth factor;GO:0008219//cell death;GO:0009267//cellular response to starvation;GO:0000165//MAPK cascade;GO:0006816//calcium ion transport;GO:0097305//response to alcohol;GO:0048168//regulation of neuronal synaptic plasticity "gi|117168299|ref|NP_032197.3|/0/glutamate receptor ionotropic, NMDA 2B precursor [Mus musculus]" 211712 5454 0.066666667 0.043333333 -0.621488377 Down 0.110929332 Pcdh9 protocadherin 9 K16498|1|0.0|1941|cfa:476942|protocadherin delta 1 - - - gi|422744224|ref|NP_001258728.1|/0/protocadherin-9 isoform c [Mus musculus] 320354 2894 0.05 0.033333333 -0.584962501 Down 0.110929332 Grin1os "glutamate receptor, ionotropic, NMDA1 (zeta 1), opposite strand" "K05208|1|1e-110|114|hgl:101720185|glutamate receptor ionotropic, NMDA 1" - - - gi|528768645|gb|EPY88304.1|/1.0773e-110/glutamate [NMDA] receptor subunit zeta-1 precursor [Camelus ferus] 320178 1518 0.043333333 0.066666667 0.621488377 Up 0.110929332 4921529L05Rik RIKEN cDNA 4921529L05 gene - - - - "gi|148666280|gb|EDK98696.1|/1.0377e-41/mCG144842, partial [Mus musculus]" 329160 3728 0.033333333 0.053333333 0.678071905 Up 0.110929332 9130024F11Rik RIKEN cDNA 9130024F11 gene - - - - gi|829921641|ref|XP_012594318.1|/1.58309e-21/PREDICTED: uncharacterized protein LOC105856900 [Microcebus murinus] 13070 1774 0.033333333 0.053333333 0.678071905 Up 0.110929332 Cyp11a1 "cytochrome P450, family 11, subfamily a, polypeptide 1" K00498|1|0.0|1046|mmu:13070|cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6] GO:0005743//mitochondrial inner membrane;GO:0043025//neuronal cell body GO:0046914//transition metal ion binding;GO:0032934//sterol binding;GO:0008395//steroid hydroxylase activity;GO:0046906//tetrapyrrole binding GO:0050755//chemokine metabolic process;GO:0071363//cellular response to growth factor stimulus;GO:0032496//response to lipopolysaccharide;GO:0016125//sterol metabolic process;GO:0006700//C21-steroid hormone biosynthetic process;GO:0046677//response to antibiotic;GO:0007618//mating;GO:0006702//androgen biosynthetic process;GO:0008406//gonad development;GO:0042537//benzene-containing compound metabolic process;GO:0000302//response to reactive oxygen species;GO:0051384//response to glucocorticoid;GO:0021543//pallium development;GO:0007565//female pregnancy;GO:0006970//response to osmotic stress;GO:0034612//response to tumor necrosis factor;GO:0007422//peripheral nervous system development;GO:0033273//response to vitamin;GO:0030154//cell differentiation;GO:0051591//response to cAMP;GO:0046686//response to cadmium ion;GO:0022037//metencephalon development;GO:0010212//response to ionizing radiation;GO:0033594//response to hydroxyisoflavone;GO:0070555//response to interleukin-1;GO:0032870//cellular response to hormone stimulus;GO:0032354//response to follicle-stimulating hormone "gi|148747566|ref|NP_062753.3|/0/cholesterol side-chain cleavage enzyme, mitochondrial precursor [Mus musculus]" 12231 3454 0.03 0.046666667 0.637429921 Up 0.110929332 Btn1a1 "butyrophilin, subfamily 1, member A1" K06712|1|0.0|1032|mmu:12231|butyrophilin - - - - 110835 2738 0.036666667 0.06 0.710493383 Up 0.110929332 Chrna5 "cholinergic receptor, nicotinic, alpha polypeptide 5" K04807|1|0.0|862|mmu:110835|nicotinic acetylcholine receptor alpha-5 GO:0043005//neuron projection;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0005887//integral component of plasma membrane GO:0004888//transmembrane signaling receptor activity;GO:0042165//neurotransmitter binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0044765//single-organism transport;GO:0014070//response to organic cyclic compound;GO:0030534//adult behavior gi|46559780|ref|NP_789814.2|/0/neuronal acetylcholine receptor subunit alpha-5 [Mus musculus] 100504720 2554 0.043333333 0.026666667 -0.700439718 Down 0.110929332 2310002F09Rik RIKEN cDNA 2310002F09 gene - - - - "gi|148690727|gb|EDL22674.1|/3.62737e-43/mCG1048654, partial [Mus musculus]" 17200 1608 0.04 0.06 0.584962501 Up 0.110929332 Mc2r melanocortin 2 receptor K04200|1|1e-152|542|mmu:17200|melanocortin 2 receptor GO:0016021//integral component of membrane;GO:0044424;GO:0016021//integral component of membrane;GO:0044424;GO:0016021//integral component of membrane;GO:0044424;GO:0016021//integral component of membrane;GO:0044424 GO:0005488//binding;GO:0004977//melanocortin receptor activity;GO:0005488//binding;GO:0004977//melanocortin receptor activity;GO:0005488//binding;GO:0004977//melanocortin receptor activity;GO:0005488//binding;GO:0004977//melanocortin receptor activity GO:0006171//cAMP biosynthetic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006171//cAMP biosynthetic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006171//cAMP biosynthetic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006171//cAMP biosynthetic process;GO:0007186//G-protein coupled receptor signaling pathway gi|6678820|ref|NP_032586.1|/1.01061e-151/adrenocorticotropic hormone receptor [Mus musculus] 75953 3076 0.033333333 0.05 0.584962501 Up 0.110929332 Samd7 sterile alpha motif domain containing 7 K11457|1|9e-15|85.5|mze:101474417|polyhomeotic-like protein 2;K11456|5|1e-13|81.6|crg:105318098|polyhomeotic-like protein 1 - - - gi|254039607|ref|NP_083765.2|/0/sterile alpha motif domain-containing protein 7 [Mus musculus] 100303738 3954 0.03 0.046666667 0.637429921 Up 0.110929332 D030025P21Rik RIKEN cDNA D030025P21 gene K08023|1|2e-83|314|mmu:16997|latent transforming growth factor beta binding protein 2/3/4 GO:0044421;GO:0031988//membrane-bounded vesicle GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway "gi|148670883|gb|EDL02830.1|/1.3114e-82/latent transforming growth factor beta binding protein 2, isoform CRA_b [Mus musculus]" 16407 3813 0.043333333 0.066666667 0.621488377 Up 0.110929332 Itgae "integrin alpha E, epithelial-associated" K06524|1|0.0|2003|mmu:16407|integrin alpha E GO:0009986//cell surface;GO:0009986//cell surface - GO:0022610;GO:0022610 gi|27370456|ref|NP_766532.1|/0/integrin alpha-E isoform 2 precursor [Mus musculus] 11418 2643 0.026666667 0.043333333 0.700439718 Up 0.110929332 Asic2 acid-sensing (proton-gated) ion channel 2 K04828|1|0.0|1066|ptr:748244|acid-sensing ion channel 2 GO:0044297//cell body;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0044297//cell body;GO:0016021//integral component of membrane;GO:0030425//dendrite GO:0005272//sodium channel activity;GO:0005488//binding;GO:0005272//sodium channel activity;GO:0005488//binding GO:0042221//response to chemical;GO:0009605//response to external stimulus;GO:0007267//cell-cell signaling;GO:0050909//sensory perception of taste;GO:0006915//apoptotic process;GO:0042310//vasoconstriction;GO:0050954//sensory perception of mechanical stimulus;GO:0008104//protein localization;GO:0007165//signal transduction;GO:0034220//ion transmembrane transport;GO:0001976//neurological system process involved in regulation of systemic arterial blood pressure;GO:0006873//cellular ion homeostasis;GO:0006814//sodium ion transport;GO:0007416//synapse assembly;GO:0042221//response to chemical;GO:0009605//response to external stimulus;GO:0050909//sensory perception of taste;GO:0006915//apoptotic process;GO:0042310//vasoconstriction;GO:0050954//sensory perception of mechanical stimulus;GO:0008104//protein localization;GO:0007165//signal transduction;GO:0034220//ion transmembrane transport;GO:0001976//neurological system process involved in regulation of systemic arterial blood pressure;GO:0006873//cellular ion homeostasis;GO:0006814//sodium ion transport;GO:0007416//synapse assembly gi|77404288|ref|NP_001029185.1|/0/acid-sensing ion channel 2 isoform MDEG1 [Mus musculus] 70720 1850 0.033333333 0.053333333 0.678071905 Up 0.110929332 6330407A03Rik RIKEN cDNA 6330407A03 gene - - - - gi|12857712|dbj|BAB31087.1|/1.4839e-71/unnamed protein product [Mus musculus] 78249 2977 0.04 0.06 0.584962501 Up 0.110929332 Adgrf4 adhesion G protein-coupled receptor F4 K08457|1|0.0|1171|mmu:78249|G protein-coupled receptor 115 - - - gi|251823792|ref|NP_084343.1|/0/adhesion G protein-coupled receptor F4 precursor [Mus musculus] 117229 2402 0.043333333 0.026666667 -0.700439718 Down 0.110929332 Stk33 serine/threonine kinase 33 K08813|1|0.0|885|mmu:117229|serine/threonine kinase 33 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity;GO:0032550 GO:0006468//protein phosphorylation gi|242118010|ref|NP_473444.1|/0/serine/threonine-protein kinase 33 [Mus musculus] 624582 5159 0.03 0.046666667 0.637429921 Up 0.110929332 Morf4l1-ps1 "mortality factor 4 like 1, pseudogene 1" K11339|1|0.0|663|ecb:100059897|mortality factor 4-like protein 1 - - - - 21419 6132 0.033333333 0.05 0.584962501 Up 0.110929332 Tfap2b transcription factor AP-2 beta K09176|1|0.0|800|mmu:21419|transcription factor AP-2 alpha/beta GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0042802//identical protein binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0046983//protein dimerization activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity" "GO:0043065//positive regulation of apoptotic process;GO:0072080//nephron tubule development;GO:0035809;GO:0019318//hexose metabolic process;GO:0001656//metanephros development;GO:0055065//metal ion homeostasis;GO:0030073//insulin secretion;GO:0008544//epidermis development;GO:0030509//BMP signaling pathway;GO:0035904//aorta development;GO:0033500//carbohydrate homeostasis;GO:0072506;GO:0048844//artery morphogenesis;GO:0030154//cell differentiation;GO:0008283//cell proliferation;GO:0048483//autonomic nervous system development;GO:0035108//limb morphogenesis;GO:0003407//neural retina development;GO:0055082//cellular chemical homeostasis;GO:0006351//transcription, DNA-templated" gi|568905315|ref|XP_006495555.1|/0/PREDICTED: transcription factor AP-2-beta isoform X2 [Mus musculus] 319984 4489 0.033333333 0.053333333 0.678071905 Up 0.110929332 Jph4 junctophilin 4 K19530|1|0.0|992|mmu:319984|junctophilin GO:0031224//intrinsic component of membrane;GO:0030425//dendrite;GO:0033017//sarcoplasmic reticulum membrane - GO:0050905//neuromuscular process;GO:0050804//modulation of synaptic transmission;GO:1901019//regulation of calcium ion transmembrane transporter activity;GO:0007611//learning or memory;GO:0007204//positive regulation of cytosolic calcium ion concentration gi|31982212|ref|NP_796023.2|/0/junctophilin-4 [Mus musculus] 72090 2306 0.026666667 0.043333333 0.700439718 Up 0.110929332 Entpd8 ectonucleoside triphosphate diphosphohydrolase 8 K01510|1|0.0|1014|mmu:72090|apyrase [EC:3.6.1.5] GO:0031224//intrinsic component of membrane GO:0016462//pyrophosphatase activity;GO:0032550 GO:0009123;GO:0009132//nucleoside diphosphate metabolic process "gi|148676252|gb|EDL08199.1|/0/mCG20282, isoform CRA_a, partial [Mus musculus]" 56485 3096 0.036666667 0.06 0.710493383 Up 0.110929332 Slc2a5 "solute carrier family 2 (facilitated glucose transporter), member 5" "K08143|1|0.0|919|mmu:56485|MFS transporter, SP family, solute carrier family 2 (facilitated glucose/fructose transporter), member 5" GO:0031224//intrinsic component of membrane GO:0015149//hexose transmembrane transporter activity GO:0044763;GO:0008645//hexose transport;GO:0044710;GO:0044238//primary metabolic process "gi|31543728|ref|NP_062715.2|/0/solute carrier family 2, facilitated glucose transporter member 5 [Mus musculus]" 235435 2187 0.03 0.046666667 0.637429921 Up 0.110929332 Lctl lactase-like K01229|1|6e-137|490|bfo:BRAFLDRAFT_105101|lactase-phlorizin hydrolase [EC:3.2.1.108 3.2.1.62] GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle "GO:0016798//hydrolase activity, acting on glycosyl bonds" GO:0044238//primary metabolic process gi|22003882|ref|NP_665834.1|/0/lactase-like protein precursor [Mus musculus] 320343 3495 0.033333333 0.053333333 0.678071905 Up 0.110929332 Lypd6 LY6/PLAUR domain containing 6 K08576|1|2e-12|77.8|bfo:BRAFLDRAFT_132644|calpain-7 [EC:3.4.22.-] - - - gi|28893103|ref|NP_796113.1|/9.65386e-90/ly6/PLAUR domain-containing protein 6 precursor [Mus musculus] 77595 5681 0.063333333 0.04 -0.662965013 Down 0.110929332 Nup210l nucleoporin 210-like K14314|1|0.0|3706|mmu:77595|nuclear pore complex protein Nup210 GO:0031224//intrinsic component of membrane - - gi|254675162|ref|NP_084213.1|/0/nuclear pore membrane glycoprotein 210-like precursor [Mus musculus] 100270707 1901 0.033333333 0.053333333 0.678071905 Up 0.110929332 Gm14379 predicted gene 14379 K11366|1|4e-12|62.0|ssc:100515460|ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12] - - - - 12353 1380 0.043333333 0.066666667 0.621488377 Up 0.110929332 Car6 carbonic anhydrase 6 K01672|1|3e-177|623|mmu:12353|carbonic anhydrase [EC:4.2.1.1] GO:0044424;GO:0044421 GO:0046914//transition metal ion binding;GO:0016836//hydro-lyase activity GO:0044237//cellular metabolic process "gi|29612611|gb|AAH49973.1|/3.29589e-177/Car6 protein, partial [Mus musculus]" 56734 1530 0.04 0.06 0.584962501 Up 0.110929332 Tulp2 tubby-like protein 2 K19600|1|6e-94|347|cmy:102935323|tubby-related protein 1 GO:0044424;GO:0044424;GO:0044424 GO:0042578//phosphoric ester hydrolase activity;GO:0042578//phosphoric ester hydrolase activity;GO:0042578//phosphoric ester hydrolase activity - "gi|148690916|gb|EDL22863.1|/0/tubby-like protein 2, isoform CRA_b, partial [Mus musculus]" 211482 2661 0.06 0.036666667 -0.710493383 Down 0.110929332 Efhb "EF hand domain family, member B" - - GO:0043169//cation binding - gi|255003729|ref|NP_766085.2|/0/EF-hand domain-containing family member B [Mus musculus] 52372 2224.01 0.046666667 0.03 -0.637429921 Down 0.110929332 D6Ertd527e "DNA segment, Chr 6, ERATO Doi 527, expressed" - - - - gi|269308207|ref|NP_001161410.1|/1.99515e-34/mucin-21 isoform b [Mus musculus] 625424 2261 0.043333333 0.026666667 -0.700439718 Down 0.110929332 Gm6583 predicted gene 6583 K18730|1|1e-06|58.2|sko:100376891|PERQ amino acid-rich with GYF domain-containing protein;K11515|2|9e-06|55.1|phd:102340686|inner centromere protein - - - gi|254540148|ref|NP_001034317.2|/0/uncharacterized protein LOC625424 [Mus musculus] 13193 9000 0.05 0.033333333 -0.584962501 Down 0.110929332 Dcx doublecortin K16579|1|0.0|709|ngi:103750015|neuronal migration protein doublecortin GO:0015630//microtubule cytoskeleton;GO:0043005//neuron projection;GO:0044444//cytoplasmic part GO:0019900//kinase binding;GO:0015631//tubulin binding GO:0016477//cell migration;GO:0016358//dendrite development;GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0021955//central nervous system neuron axonogenesis gi|672088293|ref|XP_008771670.1|/0/PREDICTED: neuronal migration protein doublecortin isoform X5 [Rattus norvegicus] 14412 2150 0.07 0.046666667 -0.584962501 Down 0.110929332 Slc6a13 "solute carrier family 6 (neurotransmitter transporter, GABA), member 13" "K05039|1|0.0|1223|mmu:14412|solute carrier family 6 (neurotransmitter transporter, GABA) member 6/8/11/12/13" GO:0016021//integral component of membrane GO:0005488//binding;GO:0005283//sodium:amino acid symporter activity GO:0044765//single-organism transport gi|568940660|ref|XP_006505600.1|/0/PREDICTED: sodium- and chloride-dependent GABA transporter 2 isoform X1 [Mus musculus] 101202 2236 0.026666667 0.043333333 0.700439718 Up 0.110929332 Hepacam2 HEPACAM family member 2 K06499|1|1e-18|97.8|dre:100319064|carcinoembryonic antigen-related cell adhesion molecule GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0031023//microtubule organizing center organization;GO:0007067//mitotic nuclear division gi|30725744|ref|NP_849230.1|/0/HEPACAM family member 2 precursor [Mus musculus] 12482 2057 0.033333333 0.053333333 0.678071905 Up 0.110929332 Ms4a1 "membrane-spanning 4-domains, subfamily A, member 1" "K06466|1|6e-139|497|mmu:12482|membrane-spanning 4-domains, subfamily A, member 1" GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0031981//nuclear lumen - GO:0046649//lymphocyte activation gi|6671710|ref|NP_031667.1|/5.12241e-138/B-lymphocyte antigen CD20 [Mus musculus] 16918 3323 0.06 0.04 -0.584962501 Down 0.110929332 Mycl v-myc avian myelocytomatosis viral oncogene lung carcinoma derived K09110|1|1e-168|596|ngi:103735135|L-myc proto-oncogene protein - GO:0005515//protein binding;GO:0005515//protein binding - gi|734703994|ref|NP_001290050.1|/1.79601e-178/protein L-Myc isoform 2 [Mus musculus] 16161 2873 0.04 0.063333333 0.662965013 Up 0.110929332 Il12rb1 "interleukin 12 receptor, beta 1" K05063|1|0.0|1547|mmu:16161|interleukin 12 receptor beta-1 - - - gi|159110576|ref|NP_032379.2|/0/interleukin-12 receptor subunit beta-1 precursor [Mus musculus] 14347 1756 0.033333333 0.053333333 0.678071905 Up 0.110929332 Fut7 fucosyltransferase 7 "K07635|1|0.0|653|mmu:14347|galactoside alpha-1,3-fucosyltransferase 7 [EC:2.4.1.-]" GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0016758//transferase activity, transferring hexosyl groups;GO:0016758//transferase activity, transferring hexosyl groups;GO:0016758//transferase activity, transferring hexosyl groups;GO:0016758//transferase activity, transferring hexosyl groups;GO:0016758//transferase activity, transferring hexosyl groups;GO:0016758//transferase activity, transferring hexosyl groups;GO:0016758//transferase activity, transferring hexosyl groups" GO:0002252;GO:0006464//cellular protein modification process;GO:0070085//glycosylation;GO:0002252;GO:0006464//cellular protein modification process;GO:0070085//glycosylation;GO:0002252;GO:0006464//cellular protein modification process;GO:0070085//glycosylation;GO:0002252;GO:0006464//cellular protein modification process;GO:0070085//glycosylation;GO:0002252;GO:0006464//cellular protein modification process;GO:0070085//glycosylation;GO:0002252;GO:0006464//cellular protein modification process;GO:0070085//glycosylation;GO:0002252;GO:0006464//cellular protein modification process;GO:0070085//glycosylation "gi|755497180|ref|XP_011237324.1|/0/PREDICTED: alpha-(1,3)-fucosyltransferase 7 isoform X2 [Mus musculus]" 22361 2416 0.063333333 0.04 -0.662965013 Down 0.110929332 Vnn1 vanin 1 K08069|1|0.0|1055|mmu:22361|pantetheine hydrolase [EC:3.5.1.92] GO:0031224//intrinsic component of membrane;GO:0044421 "GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0035091//phosphatidylinositol binding" GO:0006575//cellular modified amino acid metabolic process;GO:0006954//inflammatory response;GO:0006915//apoptotic process;GO:0007155//cell adhesion;GO:0033077//T cell differentiation in thymus gi|251823855|ref|NP_035834.2|/0/pantetheinase precursor [Mus musculus] 14375 2113 11.28 11.09333333 -0.024074135 Down 0.110919929 Xrcc6 X-ray repair complementing defective repair in Chinese hamster cells 6 K10884|1|0.0|1149|mmu:14375|ATP-dependent DNA helicase 2 subunit 1 GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0043232 GO:0016835//carbon-oxygen lyase activity;GO:0032550;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0000975//regulatory region DNA binding;GO:0003690//double-stranded DNA binding;GO:0003678//DNA helicase activity GO:0002562;GO:0010165//response to X-ray;GO:0000726;GO:0007417//central nervous system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0010720//positive regulation of cell development;GO:0042538//hyperosmotic salinity response "gi|148672589|gb|EDL04536.1|/0/X-ray repair complementing defective repair in Chinese hamster cells 6, isoform CRA_a, partial [Mus musculus]" 100198 4698.93 13.59666667 13.40333333 -0.020661171 Down 0.110919929 H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) K13937|1|0.0|1567|mmu:100198|hexose-6-phosphate dehydrogenase [EC:1.1.1.47 3.1.1.31] - - - - 55988 2195.61 11.27333333 11.08666667 -0.024088491 Down 0.110919929 Snx12 sorting nexin 12 K17918|1|2e-109|397|cge:100756869|sorting nexin-3/12 - - - "gi|149042204|gb|EDL95911.1|/1.41523e-116/rCG36369, isoform CRA_b [Rattus norvegicus]" 13521 3863 0.27 0.24 -0.169925001 Down 0.110835308 Slc26a2 "solute carrier family 26 (sulfate transporter), member 2" "K14701|1|0.0|1352|mmu:13521|solute carrier family 26 (sulfate anion transporter), member 2" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity GO:0044763;GO:0015698//inorganic anion transport gi|6681233|ref|NP_031911.1|/0/sulfate transporter [Mus musculus] 320581 2243 0.22 0.246666667 0.165059246 Up 0.110835308 Idi2 isopentenyl-diphosphate delta isomerase 2 K01823|1|1e-111|406|mmu:320581|isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2] - - - - 665119 2337 0.236666667 0.266666667 0.172180975 Up 0.110835308 Sec14l5 SEC14-like lipid binding 5 K16302|1|6e-39|165|tru:101066937|metal transporter CNNM;K17981|2|1e-29|134|fch:102055515|mitochondrial fission process protein 1;K19625|3|9e-06|55.1|xtr:448050|retinaldehyde-binding protein 1 GO:0044464;GO:0031224//intrinsic component of membrane - - gi|189181692|ref|NP_001121197.1|/0/SEC14-like protein 5 [Mus musculus] 207686 3245 0.24 0.213333333 -0.169925001 Down 0.110835308 Cfap69 cilia and flagella associated protein 69 K01277|1|8e-19|99.0|aqu:100641989|dipeptidyl-peptidase III [EC:3.4.14.4] - - - gi|27369597|ref|NP_766035.1|/0/cilia- and flagella-associated protein 69 [Mus musculus] 70592 1735 0.26 0.293333333 0.1740294 Up 0.110835308 5730480H06Rik RIKEN cDNA 5730480H06 gene - - - - - 22688 11407 0.65 0.606666667 -0.099535674 Down 0.110769491 Zfp26 zinc finger protein 26 K09228|1|0.0|2012|mmu:22688|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|219281822|ref|NP_035883.2|/0/zinc finger protein 26 [Mus musculus] 435518 2342 0.636666667 0.593333333 -0.101695397 Down 0.110769491 Pdxk-ps "pyridoxal (pyridoxine, vitamin B6) kinase, pseudogene" K00868|1|7e-99|193|cge:100751202|pyridoxine kinase [EC:2.7.1.35] - - - - 16576 4522.21 0.593333333 0.553333333 -0.100694 Down 0.110769491 Kif7 kinesin family member 7 K18806|1|0.0|2191|mmu:16576|kinesin family member 7 GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0032550;GO:0003774//motor activity;GO:0032550;GO:0003774//motor activity GO:0007224//smoothened signaling pathway;GO:0006928//movement of cell or subcellular component;GO:0007224//smoothened signaling pathway;GO:0006928//movement of cell or subcellular component gi|601983875|ref|NP_001278151.1|/0/kinesin-like protein KIF7 isoform 1 [Mus musculus] 231002 2210 0.583333333 0.543333333 -0.102482958 Down 0.110769491 Plekhn1 "pleckstrin homology domain containing, family N member 1" K13710|1|9e-11|71.6|ptg:102952488|Rho guanine nucleotide exchange factor 7 - - - gi|289666803|ref|NP_001008234.2|/0/probable pleckstrin homology domain-containing family N member 1 [Mus musculus] 12984 4570.34 0.573333333 0.533333333 -0.10433666 Down 0.110769491 Csf2rb2 "colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)" K04738|1|0.0|1670|mmu:12984|cytokine receptor common subunit beta GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding GO:0002237//response to molecule of bacterial origin;GO:0007166//cell surface receptor signaling pathway;GO:0002237//response to molecule of bacterial origin;GO:0007166//cell surface receptor signaling pathway "gi|148697721|gb|EDL29668.1|/0/mCG13356, isoform CRA_a [Mus musculus]" 219103 4385 0.623333333 0.58 -0.103950964 Down 0.110769491 Cenpj centromere protein J K11502|1|0.0|2379|mmu:219103|centromere protein J - - - gi|225543405|ref|NP_001014996.2|/0/centromere protein J [Mus musculus] 170823 2001 0.593333333 0.636666667 0.101695397 Up 0.110769491 Glmn "glomulin, FKBP associated protein" - GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0080008//Cul4-RING E3 ubiquitin ligase complex GO:0044389//ubiquitin-like protein ligase binding;GO:0055104;GO:0070851//growth factor receptor binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0055104;GO:0070851//growth factor receptor binding GO:0014020;GO:0050663//cytokine secretion;GO:0010468//regulation of gene expression;GO:0016310//phosphorylation;GO:0042094//interleukin-2 biosynthetic process;GO:0016567//protein ubiquitination;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0061136//regulation of proteasomal protein catabolic process;GO:0042098//T cell proliferation;GO:0014020;GO:0050663//cytokine secretion;GO:0010468//regulation of gene expression;GO:0016310//phosphorylation;GO:0042094//interleukin-2 biosynthetic process;GO:0016567//protein ubiquitination;GO:0007165//signal transduction;GO:0030154//cell differentiation;GO:0061136//regulation of proteasomal protein catabolic process;GO:0042098//T cell proliferation gi|239985596|ref|NP_573511.2|/0/glomulin isoform a [Mus musculus] 67102 5927 0.606666667 0.566666667 -0.098403704 Down 0.110769491 D16Ertd472e "DNA segment, Chr 16, ERATO Doi 472, expressed" - - - - gi|165972317|ref|NP_080243.3|/1.92002e-165/protein EURL homolog [Mus musculus] 67161 3020 0.586666667 0.626666667 0.095157233 Up 0.110769491 Sclt1 sodium channel and clathrin linker 1 K06102|1|3e-24|117|fca:101100990|cingulin GO:0005815//microtubule organizing center;GO:0030118//clathrin coat GO:0005515//protein binding;GO:0016247//channel regulator activity GO:0045161//neuronal ion channel clustering gi|124487197|ref|NP_001074880.1|/0/sodium channel and clathrin linker 1 [Mus musculus] 76866 1661 0.51 0.546666667 0.100164162 Up 0.110769491 Morn1 MORN repeat containing 1 K19755|1|6e-24|114|tad:TRIADDRAFT_63914|radial spoke head protein 1 - - - gi|124487378|ref|NP_001074569.1|/0/MORN repeat-containing protein 1 [Mus musculus] 69480 4793 0.646666667 0.603333333 -0.100066955 Down 0.110769491 Ttc9 tetratricopeptide repeat domain 9 K05864|1|1e-09|69.3|tru:101066949|peptidyl-prolyl isomerase D [EC:5.2.1.8];K20097|2|1e-09|68.9|bfo:BRAFLDRAFT_225521|FK506-binding protein-like;K09572|3|5e-09|67.0|obi:106883682|FK506-binding protein 6 [EC:5.2.1.8];K09574|4|2e-08|65.5|sko:100378510|FK506-binding protein 8 [EC:5.2.1.8] - - - - 217265 8339 0.5 0.536666667 0.102098188 Up 0.110769491 Abca5 "ATP-binding cassette, sub-family A (ABC1), member 5" "K05648|1|0.0|3095|mmu:217265|ATP-binding cassette, subfamily A (ABC1), member 5" GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0005770//late endosome GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0030301//cholesterol transport;GO:0010742//macrophage derived foam cell differentiation;GO:0034369//plasma lipoprotein particle remodeling gi|146134400|ref|NP_671752.2|/0/ATP-binding cassette sub-family A member 5 [Mus musculus] 14788 2676 0.663333333 0.62 -0.097465809 Down 0.110769491 Gpr162 G protein-coupled receptor 162 K08440|1|0.0|840|mmu:14788|G protein-coupled receptor 162 GO:0016020//membrane GO:0004871//signal transducer activity GO:0007165//signal transduction gi|7305103|ref|NP_038561.1|/0/probable G-protein coupled receptor 162 [Mus musculus] 69668 1721 11.13666667 10.95666667 -0.023508526 Down 0.11048742 Ccdc115 coiled-coil domain containing 115 - GO:0000323//lytic vacuole - - gi|58037169|ref|NP_081435.1|/4.26375e-95/coiled-coil domain-containing protein 115 [Mus musculus] 20708 1859 16.18333333 16.00333333 -0.01613636 Down 0.11048742 Serpinb6b "serine (or cysteine) peptidase inhibitor, clade B, member 6b" K13963|1|0.0|713|mmu:20708|serpin B - - - "gi|15826844|ref|NP_035584.1|/0/serine (or cysteine) proteinase inhibitor, clade B, member 6b [Mus musculus]" 83435 3007 11.55666667 11.37333333 -0.02307019 Down 0.11048742 Plekha3 "pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3" K20313|1|5e-154|548|mmu:83435|pleckstrin homology domain-containing family A member 3 GO:0043231//intracellular membrane-bounded organelle GO:0035091//phosphatidylinositol binding - gi|13752585|ref|NP_112546.1|/3.97997e-153/pleckstrin homology domain-containing family A member 3 [Mus musculus] 99543 1736 13.54 13.36333333 -0.018947822 Down 0.11048742 Olfml3 olfactomedin-like 3 K19909|1|6e-57|224|ngi:103748885|synaptotagmin-9;K04593|3|5e-28|128|mze:101471113|latrophilin 2;K04592|4|1e-27|127|ngi:103751849|latrophilin 1 - - GO:0032502//developmental process gi|86439989|ref|NP_598620.2|/0/olfactomedin-like protein 3 precursor [Mus musculus] 217218 3704.39 12.39666667 12.21666667 -0.02110155 Down 0.11048742 Atxn7l3 ataxin 7-like 3 K11363|1|2e-158|563|cge:100754412|SAGA-associated factor 11 - - - gi|913515982|ref|XP_013209897.1|/1.5093e-157/PREDICTED: ataxin-7-like protein 3 isoform X3 [Microtus ochrogaster] 103583 4227.61 16.44 16.61666667 0.015420705 Up 0.11048742 Fbxw11 F-box and WD-40 domain protein 11 K03362|1|0.0|1080|ecb:100069972|F-box and WD-40 domain protein 1/11 - - - - 11863 4348.61 15.67666667 15.5 -0.016350616 Down 0.11048742 Arnt aryl hydrocarbon receptor nuclear translocator K09097|1|0.0|1464|mmu:11863|aryl hydrocarbon receptor nuclear translocator GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0005102//receptor binding;GO:0038023//signaling receptor activity;GO:0003712//transcription cofactor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0005102//receptor binding;GO:0038023//signaling receptor activity;GO:0003712//transcription cofactor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003677//DNA binding" GO:0010556;GO:0006366//transcription from RNA polymerase II promoter;GO:0031328//positive regulation of cellular biosynthetic process;GO:0001819//positive regulation of cytokine production;GO:0007165//signal transduction;GO:0048869//cellular developmental process;GO:0016925//protein sumoylation;GO:0034599//cellular response to oxidative stress;GO:0001701//in utero embryonic development;GO:0010556;GO:0006366//transcription from RNA polymerase II promoter;GO:0031328//positive regulation of cellular biosynthetic process;GO:0001819//positive regulation of cytokine production;GO:0007165//signal transduction;GO:0048869//cellular developmental process;GO:0016925//protein sumoylation;GO:0034599//cellular response to oxidative stress;GO:0001701//in utero embryonic development gi|83627702|ref|NP_033839.2|/0/aryl hydrocarbon receptor nuclear translocator isoform b [Mus musculus] 20405 2089 10.63666667 10.46 -0.024163256 Down 0.11048742 Sh3gl1 SH3-domain GRB2-like 1 K11247|1|7e-144|422|ola:101164792|endophilin-A GO:0005769//early endosome GO:0019899//enzyme binding GO:0016192//vesicle-mediated transport gi|7305485|ref|NP_038692.1|/0/endophilin-A2 isoform 1 [Mus musculus] 68449 3614 10.85333333 11.03666667 0.024166311 Up 0.11048742 Tbc1d10b "TBC1 domain family, member 10b" K19944|1|0.0|1137|mmu:68449|TBC1 domain family member 10 - - - "gi|148685561|gb|EDL17508.1|/0/TBC1 domain family, member 10b, partial [Mus musculus]" 67031 1402 11.15333333 10.97666667 -0.023034933 Down 0.11048742 Upf3a UPF3 regulator of nonsense transcripts homolog A (yeast) K14328|1|0.0|677|mmu:67031|regulator of nonsense transcripts 3 GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0005488//binding GO:0006412//translation;GO:0006810//transport;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0035966//response to topologically incorrect protein gi|21313164|ref|NP_080200.1|/0/regulator of nonsense transcripts 3A [Mus musculus] 18130 5019 1.813333333 1.876666667 0.049528271 Up 0.110374591 Ints6 integrator complex subunit 6 K13143|1|0.0|1798|mmu:18130|integrator complex subunit 6 "GO:0005856//cytoskeleton;GO:0016591//DNA-directed RNA polymerase II, holoenzyme" - GO:0016073//snRNA metabolic process gi|51467749|ref|NP_032741.2|/0/integrator complex subunit 6 [Mus musculus] 13368 2073 1.673333333 1.736666667 0.053596008 Up 0.110374591 Dffb "DNA fragmentation factor, beta subunit" "K02311|1|0.0|679|mmu:13368|DNA fragmentation factor, 40 kD, beta subunit [EC:3.-.-.-]" GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin "GO:0003676//nucleic acid binding;GO:0016763//transferase activity, transferring pentosyl groups;GO:0005515//protein binding;GO:0004518//nuclease activity" "GO:0012502//induction of programmed cell death;GO:0030261//chromosome condensation;GO:0000737//DNA catabolic process, endonucleolytic" gi|160948620|ref|NP_031885.3|/0/DNA fragmentation factor subunit beta [Mus musculus] 11480 5681 1.85 1.79 -0.047565683 Down 0.110374591 Acvr2a activin receptor IIA K04670|1|0.0|966|ocu:100008631|activin receptor type-2A [EC:2.7.11.30] GO:0043234//protein complex;GO:0005887//integral component of plasma membrane;GO:0044424 GO:0017002//activin-activated receptor activity;GO:0032403//protein complex binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0043169//cation binding GO:0007369//gastrulation;GO:0001501//skeletal system development;GO:0030282//bone mineralization;GO:0008406//gonad development;GO:0032924//activin receptor signaling pathway;GO:0048232//male gamete generation;GO:0001934//positive regulation of protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0001649//osteoblast differentiation;GO:0032278;GO:0042221//response to chemical;GO:0008283//cell proliferation;GO:0032768;GO:0003002//regionalization;GO:0030218//erythrocyte differentiation;GO:0009855//determination of bilateral symmetry;GO:0007320//insemination "gi|281353901|gb|EFB29485.1|/0/hypothetical protein PANDA_012344, partial [Ailuropoda melanoleuca]" 67728 2526 1.74 1.796666667 0.046235466 Up 0.110374591 Dph2 DPH2 homolog K17866|1|0.0|935|mmu:67728|diphthamide biosynthesis protein 2 - - - - 22401 7784 1.82 1.763333333 -0.045633229 Down 0.110374591 Zmat3 zinc finger matrin type 3 "K10137|1|6e-165|585|mmu:22401|zinc finger, matrin type 3" GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0012502//induction of programmed cell death;GO:0016049//cell growth;GO:0033554//cellular response to stress;GO:0045184//establishment of protein localization gi|101943566|ref|NP_033543.2|/4.82341e-164/zinc finger matrin-type protein 3 [Mus musculus] 329003 7713.12 1.833333333 1.77 -0.050719758 Down 0.110374591 Zfp516 zinc finger protein 516 K09228|1|6e-28|130|bfo:BRAFLDRAFT_80523|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|33942118|ref|NP_898854.1|/0/zinc finger protein 516 [Mus musculus] 229227 15883 1.73 1.67 -0.050923935 Down 0.110374591 4932438A13Rik RIKEN cDNA 4932438A13 gene K05741|1|1e-115|422|isc:IscW_ISCW017338|diaphanous 2 - - - gi|225543434|ref|NP_766267.2|/0/uncharacterized protein KIAA1109 [Mus musculus] 668215 2662 1.736666667 1.673333333 -0.053596008 Down 0.110374591 1500017E21Rik RIKEN cDNA 1500017E21 gene - - - - "gi|148709827|gb|EDL41773.1|/1.50326e-31/mCG146175, partial [Mus musculus]" 329096 3200 1.636666667 1.7 0.054774223 Up 0.110374591 Gm17644 "predicted gene, 17644" K04613|1|7e-09|65.9|rno:297590|vomeronasal 2 receptor - - - gi|68070859|ref|XP_677343.1|/9.41479e-68/hypothetical protein [Plasmodium berghei strain ANKA] [Plasmodium berghei ANKA] 69962 1475 1.816666667 1.753333333 -0.05119343 Down 0.110374591 Mettl18 methyltransferase like 18 - GO:0044424 GO:0008168//methyltransferase activity GO:0008213 gi|31980620|ref|NP_081555.2|/0/histidine protein methyltransferase 1 homolog [Mus musculus] 434756 1792 0.036666667 0.053333333 0.540568381 Up 0.110130129 Akap14 A kinase (PRKA) anchor protein 14 K16530|1|2e-106|389|mmu:434756|A-kinase anchor protein 14 GO:0005929//cilium "GO:0005515//protein binding;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006796//phosphate-containing compound metabolic process;GO:0048232//male gamete generation gi|148697046|gb|EDL28993.1|/1.65026e-105/mCG116474 [Mus musculus] 77577 1819 0.036666667 0.053333333 0.540568381 Up 0.110130129 Spns3 spinster homolog 3 "K20225|1|2e-115|419|acs:103282837|capicua transcriptional repressor;K08202|2|9e-06|54.7|bfo:BRAFLDRAFT_226384|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 4/5" GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763;GO:0010876//lipid localization gi|58037493|ref|NP_084208.1|/0/protein spinster homolog 3 [Mus musculus] 15233 1619 0.04 0.056666667 0.502500341 Up 0.110130129 Hgd "homogentisate 1, 2-dioxygenase" "K00451|1|0.0|823|mmu:15233|homogentisate 1,2-dioxygenase [EC:1.13.11.5]" - "GO:0043169//cation binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen" GO:0006558//L-phenylalanine metabolic process;GO:0006570//tyrosine metabolic process "gi|148665546|gb|EDK97962.1|/0/homogentisate 1, 2-dioxygenase, isoform CRA_b, partial [Mus musculus]" 22776 3528 0.053333333 0.076666667 0.523561956 Up 0.110130129 Zim1 "zinc finger, imprinted 1" K09228|1|0.0|1108|mmu:22776|KRAB domain-containing zinc finger protein GO:0044464 GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" "gi|148699378|gb|EDL31325.1|/0/zinc finger, imprinted 1, isoform CRA_a, partial [Mus musculus]" 239606 6541 0.036666667 0.053333333 0.540568381 Up 0.110130129 Slc2a13 "solute carrier family 2 (facilitated glucose transporter), member 13" "K08150|1|0.0|1089|mmu:239606|MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13" GO:0031224//intrinsic component of membrane GO:0022857//transmembrane transporter activity GO:0044763 gi|203099104|ref|NP_001028805.2|/0/proton myo-inositol cotransporter [Mus musculus] 13497 6983 0.046666667 0.066666667 0.514573173 Up 0.110130129 Drp2 dystrophin related protein 2 K10366|1|0.0|971|lcm:102348135|dystrophin GO:0043005//neuron projection;GO:0016020//membrane;GO:0043232 GO:0046914//transition metal ion binding GO:0016043//cellular component organization "gi|148688453|gb|EDL20400.1|/0/dystrophin related protein 2, isoform CRA_b, partial [Mus musculus]" 320772 9813 0.063333333 0.043333333 -0.547487795 Down 0.110130129 Mdga2 MAM domain containing glycosylphosphatidylinositol anchor 2 K17341|1|7e-35|154|dre:565032|hemicentin - - - gi|74200521|dbj|BAE23453.1|/0/unnamed protein product [Mus musculus] 381113 2931 0.07 0.05 -0.485426827 Down 0.110130129 Cdkl4 cyclin-dependent kinase-like 4 K08824|1|0.0|667|mmu:381113|cyclin-dependent kinase-like [EC:2.7.11.22] GO:0044424 GO:0004674//protein serine/threonine kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|84370314|ref|NP_001028615.1|/0/cyclin-dependent kinase-like 4 [Mus musculus] 381347 4066 0.04 0.056666667 0.502500341 Up 0.110130129 4930412O13Rik RIKEN cDNA 4930412O13 gene - - - - - 19217 3768 0.07 0.05 -0.485426827 Down 0.110130129 Ptger2 prostaglandin E receptor 2 (subtype EP2) K04259|1|3e-127|459|mmu:19217|prostaglandin E receptor 2 GO:0016021//integral component of membrane GO:0004955//prostaglandin receptor activity GO:0034695//response to prostaglandin E;GO:0002237//response to molecule of bacterial origin;GO:0008283//cell proliferation;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway gi|6679529|ref|NP_032990.1|/2.39813e-126/prostaglandin E2 receptor EP2 subtype [Mus musculus] 320225 3566 0.053333333 0.076666667 0.523561956 Up 0.110130129 Catsperg1 catsper channel auxiliary subunit gamma 1 K16894|1|0.0|2056|mmu:76718|cation channel sperm-associated protein subunit gamma GO:0005929//cilium;GO:0005891//voltage-gated calcium channel complex - GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|568945966|ref|XP_006540142.1|/0/PREDICTED: cation channel sperm-associated protein subunit gamma 1 isoform X5 [Mus musculus] 26361 4148 0.073333333 0.05 -0.552541023 Down 0.110130129 Avpr1b arginine vasopressin receptor 1B K04227|1|0.0|795|mmu:26361|arginine vasopressin receptor 1B - - - - 234404 2785 0.073333333 0.05 -0.552541023 Down 0.110130129 Nxnl1 nucleoredoxin-like 1 K17609|1|4e-25|119|mdo:100025089|nucleoredoxin [EC:1.8.1.8] GO:0043231//intracellular membrane-bounded organelle - - gi|21704204|ref|NP_663573.1|/3.56036e-108/nucleoredoxin-like protein 1 [Mus musculus] 74513 5646 0.08 0.056666667 -0.497499659 Down 0.110130129 Neto2 neuropilin (NRP) and tolloid (TLL)-like 2 K14616|1|6e-30|136|rro:104655345|cubilin GO:0031224//intrinsic component of membrane - - gi|124486763|ref|NP_001074793.1|/0/neuropilin and tolloid-like protein 2 [Mus musculus] 100502932 2940 0.053333333 0.076666667 0.523561956 Up 0.110130129 Gm13544 predicted gene 13544 K13568|1|4e-25|119|ngi:103741051|activin receptor type-1C [EC:2.7.11.30] - - - - 503610 2847 13.15 12.98333333 -0.018401972 Down 0.110111324 Zdhhc18 "zinc finger, DHHC domain containing 18" K16675|1|2e-172|608|mmu:503610|palmitoyltransferase ZDHHC9/14/18 [EC:2.3.1.225] GO:0031224//intrinsic component of membrane "GO:0046914//transition metal ion binding;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups" GO:0008104//protein localization gi|114326532|ref|NP_001017968.2|/1.77921e-171/palmitoyltransferase ZDHHC18 [Mus musculus] 72198 3309 10.39 10.22333333 -0.023329988 Down 0.110111324 Skiv2l2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) K12598|1|0.0|1907|mmu:72198|ATP-dependent RNA helicase DOB1 [EC:3.6.4.13] GO:0043234//protein complex;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen "GO:0032550;GO:0042623//ATPase activity, coupled" GO:0000377;GO:0006364//rRNA processing gi|21312352|ref|NP_082427.1|/0/superkiller viralicidic activity 2-like 2 [Mus musculus] 268996 3061.2 11.66 11.83333333 0.021288735 Up 0.110111324 Ss18 "synovial sarcoma translocation, Chromosome 18" K15623|1|4e-139|498|mmu:268996|protein SSXT GO:0005874//microtubule;GO:0005874//microtubule;GO:0005874//microtubule;GO:0005874//microtubule GO:0003713//transcription coactivator activity;GO:0005488//binding;GO:0003713//transcription coactivator activity;GO:0003713//transcription coactivator activity;GO:0005488//binding;GO:0003713//transcription coactivator activity GO:0035556//intracellular signal transduction;GO:0006996//organelle organization;GO:0032989;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0035556//intracellular signal transduction;GO:0006996//organelle organization;GO:0032989;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0035556//intracellular signal transduction;GO:0006996//organelle organization;GO:0032989;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter;GO:0035556//intracellular signal transduction;GO:0006996//organelle organization;GO:0032989;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0042221//response to chemical;GO:0006366//transcription from RNA polymerase II promoter gi|238624174|ref|NP_001154842.1|/9.47259e-104/protein SSXT isoform 3 [Mus musculus] 11746 2003 13.87 14.04 0.017575148 Up 0.110111324 Anxa4 annexin A4 K17093|1|3e-177|624|mmu:11746|annexin A4 GO:0044424 GO:0046872//metal ion binding;GO:0005543//phospholipid binding;GO:0055102//lipase inhibitor activity GO:0050817//coagulation;GO:0016192//vesicle-mediated transport;GO:0006915//apoptotic process;GO:0007154//cell communication gi|161016799|ref|NP_038499.2|/2.68505e-176/annexin A4 [Mus musculus] 320938 3971 15.69666667 15.87 0.015843906 Up 0.110111324 Tnpo3 transportin 3 K15436|1|0.0|1758|mmu:320938|transportin-3 GO:0031981//nuclear lumen GO:0005488//binding GO:0006606//protein import into nucleus gi|54312056|ref|NP_796270.2|/0/transportin-3 [Mus musculus] 72421 2634 10.16666667 10.33333333 0.023458973 Up 0.110111324 Ttc30b tetratricopeptide repeat domain 30B K19683|1|0.0|1230|mmu:72421|tetratricopeptide repeat protein 30 - - - - 76687 3482 10.28 10.44666667 0.023202415 Up 0.110111324 Spcs3 signal peptidase complex subunit 3 homolog (S. cerevisiae) K12948|1|5e-99|365|chx:102172511|signal peptidase complex subunit 3 [EC:3.4.-.-] GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane GO:0016787//hydrolase activity GO:0030073//insulin secretion;GO:0015980//energy derivation by oxidation of organic compounds;GO:0006613//cotranslational protein targeting to membrane;GO:0016485//protein processing gi|926725527|ref|XP_013830814.1|/4.30626e-98/PREDICTED: signal peptidase complex subunit 3 [Capra hircus] 12305 3757.51 12.24333333 12.41333333 0.019894177 Up 0.110111324 Ddr1 "discoidin domain receptor family, member 1" K05124|1|0.0|1553|mmu:12305|discoidin domain receptor family member 1 [EC:2.7.10.1] GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459 GO:0032550;GO:0005515//protein binding;GO:0043169//cation binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032550;GO:0005515//protein binding;GO:0043169//cation binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032550;GO:0005515//protein binding;GO:0043169//cation binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032550;GO:0005515//protein binding;GO:0043169//cation binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity GO:0044703;GO:0007423//sensory organ development;GO:0008544//epidermis development;GO:0022617//extracellular matrix disassembly;GO:0007160//cell-matrix adhesion;GO:0007589//body fluid secretion;GO:0008283//cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0009887//organ morphogenesis;GO:0048754//branching morphogenesis of an epithelial tube;GO:0016049//cell growth;GO:0014812//muscle cell migration;GO:0044703;GO:0007423//sensory organ development;GO:0008544//epidermis development;GO:0022617//extracellular matrix disassembly;GO:0007160//cell-matrix adhesion;GO:0007589//body fluid secretion;GO:0008283//cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0009887//organ morphogenesis;GO:0048754//branching morphogenesis of an epithelial tube;GO:0016049//cell growth;GO:0014812//muscle cell migration;GO:0044703;GO:0007423//sensory organ development;GO:0008544//epidermis development;GO:0022617//extracellular matrix disassembly;GO:0007160//cell-matrix adhesion;GO:0007589//body fluid secretion;GO:0008283//cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0009887//organ morphogenesis;GO:0048754//branching morphogenesis of an epithelial tube;GO:0016049//cell growth;GO:0014812//muscle cell migration;GO:0044703;GO:0007423//sensory organ development;GO:0008544//epidermis development;GO:0022617//extracellular matrix disassembly;GO:0007160//cell-matrix adhesion;GO:0007589//body fluid secretion;GO:0008283//cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0009887//organ morphogenesis;GO:0048754//branching morphogenesis of an epithelial tube;GO:0016049//cell growth;GO:0014812//muscle cell migration "gi|148691279|gb|EDL23226.1|/0/discoidin domain receptor family, member 1, isoform CRA_a, partial [Mus musculus]" 140491 7120 10.73666667 10.91 0.023104942 Up 0.110111324 Ppp1r3a "protein phosphatase 1, regulatory (inhibitor) subunit 3A" K07189|1|0.0|2094|mmu:140491|protein phosphatase 1 regulatory subunit 3A/B/C/D/E GO:0031224//intrinsic component of membrane - GO:0006073//cellular glucan metabolic process;GO:0006796//phosphate-containing compound metabolic process gi|13569343|gb|AAK31072.1|/0/type 1 protein phosphatase targeting subunit RGL/GM [Mus musculus] 50995 2524 15.95666667 16.13 0.015587133 Up 0.110111324 Uba2 ubiquitin-like modifier activating enzyme 2 K10685|1|0.0|1235|mmu:50995|ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45] GO:0043231//intracellular membrane-bounded organelle GO:0008641//small protein activating enzyme activity;GO:0043169//cation binding;GO:0046983//protein dimerization activity;GO:0032550 GO:0032446//protein modification by small protein conjugation gi|7709986|ref|NP_057891.1|/0/SUMO-activating enzyme subunit 2 [Mus musculus] 69149 2339.75 2.383333333 2.316666667 -0.040930264 Down 0.109923277 Kbtbd3 kelch repeat and BTB (POZ) domain containing 3 K10471|1|0.0|1224|mmu:69149|kelch repeat and BTB domain-containing protein 3 - - - "gi|148677382|gb|EDL09329.1|/0/kelch repeat and BTB (POZ) domain containing 3, isoform CRA_b, partial [Mus musculus]" 108853 2621 2.28 2.35 0.043626932 Up 0.109923277 Mtrf1l mitochondrial translational release factor 1-like K02835|1|0.0|739|mmu:108853|peptide chain release factor 1 GO:0043231//intracellular membrane-bounded organelle GO:0003747//translation release factor activity GO:0006412//translation "gi|30425080|ref|NP_780583.1|/0/peptide chain release factor 1-like, mitochondrial precursor [Mus musculus]" 211948 3551 2.526666667 2.596666667 0.03942548 Up 0.109923277 Pde12 phosphodiesterase 12 "K19612|1|0.0|1182|mmu:211948|2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]" GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity - "gi|40538842|ref|NP_848783.3|/0/2',5'-phosphodiesterase 12 [Mus musculus]" 381835 3152 2.606666667 2.54 -0.03737761 Down 0.109923277 Sbk3 "SH3 domain binding kinase family, member 3" K08858|1|2e-133|479|mmu:381835|serine/threonine-protein kinase SBK [EC:2.7.11.1] - - - gi|565683209|sp|P0C5K0.2|SBK3_MOUSE/8.77409e-135/RecName: Full=Uncharacterized serine/threonine-protein kinase SBK3; AltName: Full=SH3-binding domain kinase family member 3; AltName: Full=Sugen kinase 110 105504 4659 2.916666667 2.846666667 -0.035046947 Down 0.109923277 Exoc5 exocyst complex component 5 K19984|1|0.0|1375|mmu:105504|exocyst complex component 5 GO:0044444//cytoplasmic part GO:0005515//protein binding GO:0048193//Golgi vesicle transport;GO:0045184//establishment of protein localization gi|46402177|ref|NP_997097.1|/0/exocyst complex component 5 [Mus musculus] 12396 6076 2.726666667 2.66 -0.035712097 Down 0.109923277 Cbfa2t2 "core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)" "K10053|1|0.0|697|oaa:100073405|runt-related transcription factor 1; translocated to, 1" GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity;GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity;GO:0046914//transition metal ion binding GO:0010556;GO:0010975//regulation of neuron projection development;GO:0006366//transcription from RNA polymerase II promoter;GO:0010556;GO:0010975//regulation of neuron projection development;GO:0006366//transcription from RNA polymerase II promoter;GO:0010556;GO:0010975//regulation of neuron projection development;GO:0006366//transcription from RNA polymerase II promoter "gi|148674125|gb|EDL06072.1|/0/core-binding factor, runt domain, alpha subunit 2, translocated to, 2 homolog (human), isoform CRA_a, partial [Mus musculus]" 217430 1928 2.713333333 2.78 0.035018589 Up 0.109923277 Pqlc3 PQ loop repeat containing - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|238550113|ref|NP_766162.2|/3.18973e-102/PQ-loop repeat-containing protein 3 isoform 1 precursor [Mus musculus] 22589 10244 2.8 2.73 -0.036525876 Down 0.109923277 Atrx alpha thalassemia/mental retardation syndrome X-linked K10779|1|0.0|3968|mmu:22589|transcriptional regulator ATRX [EC:3.6.4.12] - - - - 272538 4409 2.536666667 2.603333333 0.037426095 Up 0.109923277 Tango6 transport and golgi organization 6 K14548|1|2e-09|68.2|aam:106487434|U3 small nucleolar RNA-associated protein 4 GO:0031224//intrinsic component of membrane - - "gi|148679428|gb|EDL11375.1|/0/expressed sequence AW413431, isoform CRA_b, partial [Mus musculus]" 102631730 729 2.836666667 2.766666667 -0.036047795 Down 0.109923277 4930512M02Rik RIKEN cDNA 4930512M02 gene K04613|1|2e-10|68.2|rno:297590|vomeronasal 2 receptor;K08760|2|1e-06|55.8|hgl:101724709|apolipoprotein A-IV;K06102|3|2e-06|54.7|ecb:100059886|cingulin - - - - 381305 11011 2.88 2.81 -0.035498681 Down 0.109923277 Rc3h1 RING CCCH (C3H) domains 1 K15690|1|0.0|2014|mmu:381305|RING finger and CCCH-type zinc finger domain-containing protein GO:0035770//ribonucleoprotein granule GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0003729//mRNA binding GO:0002467//germinal center formation;GO:0022618//ribonucleoprotein complex assembly;GO:0042130//negative regulation of T cell proliferation;GO:0043487//regulation of RNA stability;GO:0030888//regulation of B cell proliferation;GO:0006402//mRNA catabolic process;GO:0002698;GO:0050852//T cell receptor signaling pathway gi|50511255|dbj|BAD32613.1|/0/mKIAA2025 protein [Mus musculus] 74470 3632 0.23 0.256666667 0.158262084 Up 0.10985746 Cep72 centrosomal protein 72 K16532|1|0.0|1180|mmu:74470|centrosomal protein CEP72 GO:0005815//microtubule organizing center GO:0005515//protein binding GO:0034629//cellular protein complex localization;GO:0000226//microtubule cytoskeleton organization gi|187960077|ref|NP_083235.3|/0/centrosomal protein of 72 kDa [Mus musculus] 77996 2302 0.256666667 0.23 -0.158262084 Down 0.10985746 Cutal cutA divalent cation tolerance homolog-like K03926|1|1e-50|156|cge:100756214|periplasmic divalent cation tolerance protein - - - "gi|148676684|gb|EDL08631.1|/3.84061e-84/RIKEN cDNA D730039F16, isoform CRA_a, partial [Mus musculus]" 66717 3584 0.26 0.29 0.157541277 Up 0.10985746 Ccdc96 coiled-coil domain containing 96 K20478|1|1e-11|75.5|mze:101467868|golgin subfamily B member 1;K18626|2|3e-10|70.9|shr:100933589|trichohyalin;K12875|4|6e-10|69.7|dre:368893|apoptotic chromatin condensation inducer in the nucleus - - - gi|13385186|ref|NP_080001.1|/0/coiled-coil domain-containing protein 96 [Mus musculus] 30944 5367 0.263333333 0.293333333 0.15565087 Up 0.10985746 Zfp354c zinc finger protein 354C K09228|1|0.0|1194|mmu:30944|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|60360270|dbj|BAD90379.1|/0/mKIAA4218 protein [Mus musculus] 338370 7115 0.083333333 0.06 -0.473931188 Down 0.109838655 Nalcn "sodium leak channel, non-selective" K04851|1|1e-66|259|lcm:102360815|voltage-dependent calcium channel L type alpha-1D;K04849|4|8e-60|236|cin:100184382|voltage-dependent calcium channel N type alpha-1B GO:0031224//intrinsic component of membrane GO:0005261//cation channel activity - gi|755548470|ref|XP_011243398.1|/0/PREDICTED: sodium leak channel non-selective protein isoform X4 [Mus musculus] 225872 3292 0.06 0.043333333 -0.469485283 Down 0.109838655 Npas4 neuronal PAS domain protein 4 K09100|1|4e-19|100|fch:102056379|single-minded GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003676//nucleic acid binding;GO:0060089;GO:0046983//protein dimerization activity GO:0007154//cell communication;GO:0006366//transcription from RNA polymerase II promoter gi|24233564|ref|NP_705781.1|/0/neuronal PAS domain-containing protein 4 [Mus musculus] 21463 1764 0.06 0.08 0.415037499 Up 0.109838655 Tcp11 t-complex protein 11 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|148277069|ref|NP_001079024.1|/0/T-complex protein 11 isoform 2 [Mus musculus] 237761 3644 0.066666667 0.09 0.432959407 Up 0.109838655 Sowaha sosondowah ankyrin repeat domain family member A K20369|1|4e-23|113|cjc:100409338|ER-derived vesicles protein;K18625|2|1e-11|75.1|umr:103663965|protein Shroom;K08803|3|1e-08|65.5|bfo:BRAFLDRAFT_93229|death-associated protein kinase [EC:2.7.11.1];K10380|4|5e-07|60.1|mze:101474584|ankyrin;K06694|5|5e-07|60.1|amj:102576751|26S proteasome non-ATPase regulatory subunit 10 - - - gi|125628646|ref|NP_898996.2|/0/ankyrin repeat domain-containing protein SOWAHA precursor [Mus musculus] 258783 1960 0.056666667 0.076666667 0.436099115 Up 0.109838655 Olfr920 olfactory receptor 920 K04257|1|1e-175|619|mmu:258783|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|257467599|ref|NP_666998.2|/1.0976e-174/olfactory receptor 920 [Mus musculus] 77323 2312 0.043333333 0.06 0.469485283 Up 0.109838655 9430041J12Rik RIKEN cDNA 9430041J12 gene K17540|1|2e-08|45.4|ssc:100737915|inactive serine/threonine-protein kinase TEX14 GO:0030175//filopodium;GO:0043005//neuron projection;GO:0005789//endoplasmic reticulum membrane;GO:0034702//ion channel complex GO:0005253//anion channel activity;GO:0046872//metal ion binding GO:0000087//mitotic M phase;GO:0007155//cell adhesion;GO:0015698//inorganic anion transport;GO:0030031//cell projection assembly "gi|148699265|gb|EDL31212.1|/1.06503e-62/mCG145494, isoform CRA_b, partial [Mus musculus]" 230459 4374 0.076666667 0.056666667 -0.436099115 Down 0.109838655 Cyp2j13 "cytochrome P450, family 2, subfamily j, polypeptide 13" "K07418|1|0.0|917|mmu:230459|cytochrome P450, family 2, subfamily J [EC:1.14.14.1]" GO:0031090//organelle membrane "GO:0046906//tetrapyrrole binding;GO:0016653//oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor;GO:0046914//transition metal ion binding;GO:0008392//arachidonic acid epoxygenase activity;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0019369//arachidonic acid metabolic process;GO:0010033//response to organic substance "gi|84370264|ref|NP_663523.2|/0/cytochrome P450, family 2, subfamily j, polypeptide 13 [Mus musculus]" 14787 2249 0.05 0.066666667 0.415037499 Up 0.109838655 Rhpn1 "rhophilin, Rho GTPase binding protein 1" "K01770|1|2e-28|130|aqu:105312342|2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12];K18040|2|3e-21|106|bmor:101736631|tyrosine-protein phosphatase non-receptor type 23 [EC:3.1.3.48]" - - GO:0019222//regulation of metabolic process;GO:0007154//cell communication;GO:0019222//regulation of metabolic process;GO:0007154//cell communication gi|254540051|ref|NP_032190.2|/0/rhophilin-1 isoform 2 [Mus musculus] 20400 824 0.09 0.066666667 -0.432959407 Down 0.109838655 Sh2d1a SH2 domain containing 1A K07990|1|8e-50|125|mmu:20400|SH2 domain protein 1A - - - - 72693 2206 0.05 0.066666667 0.415037499 Up 0.109838655 Zcchc12 "zinc finger, CCHC domain containing 12" - GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0003713//transcription coactivator activity;GO:0032182//ubiquitin-like protein binding "GO:0044093;GO:0006351//transcription, DNA-templated;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway" gi|21312230|ref|NP_082601.1|/0/zinc finger CCHC domain-containing protein 12 [Mus musculus] 102639268 2741 0.05 0.066666667 0.415037499 Up 0.109838655 Gm13830 predicted gene 13830 - - - - - 232785 4415 0.046666667 0.063333333 0.440572591 Up 0.109838655 Zfp783 zinc finger protein 783 K09228|1|3e-82|280|ngi:103734725|KRAB domain-containing zinc finger protein - - - - 106648 2157 0.053333333 0.073333333 0.459431619 Up 0.109838655 Cyp4f15 "cytochrome P450, family 4, subfamily f, polypeptide 15" "K00490|1|0.0|1023|mmu:106648|cytochrome P450, family 4, subfamily F [EC:1.14.14.1];K17726|3|0.0|882|cge:100755384|leukotriene-B4 20-monooxygenase / phylloquinone omega-hydroxylase [EC:1.14.13.30 1.14.13.194]" GO:0031090//organelle membrane "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0044710 "gi|148708351|gb|EDL40298.1|/0/cytochrome P450, family 4, subfamily f, polypeptide 15, isoform CRA_b, partial [Mus musculus]" 12507 2069 0.093333333 0.07 -0.415037499 Down 0.109838655 Cd5 CD5 antigen K06455|1|0.0|893|mmu:12507|CD5 antigen GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0038024//cargo receptor activity GO:0007165//signal transduction;GO:0031294//lymphocyte costimulation gi|126517489|ref|NP_031676.3|/0/T-cell surface glycoprotein CD5 precursor [Mus musculus] 78772 2555 0.06 0.083333333 0.473931188 Up 0.109838655 Hhipl2 hedgehog interacting protein-like 2 K15212|1|0.0|1204|ssc:100517774|TATA box-binding protein-associated factor RNA polymerase I subunit A;K06231|2|7e-75|285|phi:102114672|hedgehog interacting protein - "GO:0048037//cofactor binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0048037//cofactor binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors" - gi|261245037|ref|NP_084451.2|/0/HHIP-like protein 2 isoform 1 precursor [Mus musculus] 100554 1212 0.063333333 0.046666667 -0.440572591 Down 0.109838655 AA792892 expressed sequence AA792892 K10308|1|4e-12|75.1|myd:102753733|F-box protein 31 - - - gi|153791366|ref|NP_849225.2|/3.844e-163/uncharacterized protein LOC100554 [Mus musculus] 29859 2446 0.043333333 0.06 0.469485283 Up 0.109838655 Sult4a1 "sulfotransferase family 4A, member 1" K11823|1|8e-170|600|ngi:103743434|sulfotransferase 4A1 [EC:2.8.2.-] GO:0044444//cytoplasmic part "GO:0016782//transferase activity, transferring sulfur-containing groups" GO:0006790//sulfur compound metabolic process;GO:0006629//lipid metabolic process gi|674071606|ref|XP_008842948.1|/6.90278e-169/PREDICTED: sulfotransferase 4A1 [Nannospalax galili] 70918 2367 0.053333333 0.073333333 0.459431619 Up 0.109838655 Nsun7 "NOL1/NOP2/Sun domain family, member 7" K15264|1|2e-20|104|lcm:102350490|putative methyltransferase [EC:2.1.1.-] - GO:0003824//catalytic activity;GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process gi|725503323|ref|NP_001289762.1|/0/putative methyltransferase NSUN7 isoform 1 [Mus musculus] 73549 1702 0.08 0.06 -0.415037499 Down 0.109838655 1700110I01Rik RIKEN cDNA 1700110I01 gene K00901|1|1e-18|97.1|rno:361076|diacylglycerol kinase (ATP) [EC:2.7.1.107] - - - - 14071 2621 0.06 0.043333333 -0.469485283 Down 0.109838655 F9 coagulation factor IX K01321|1|0.0|972|mmu:14071|coagulation factor IX (Christmas factor) [EC:3.4.21.22] - GO:0046872//metal ion binding;GO:0004175//endopeptidase activity;GO:0046872//metal ion binding;GO:0004175//endopeptidase activity GO:0007599//hemostasis;GO:0019538//protein metabolic process;GO:0007599//hemostasis;GO:0019538//protein metabolic process gi|802084014|ref|NP_001292726.1|/0/coagulation factor IX isoform 2 [Mus musculus] 74405 2570 0.043333333 0.06 0.469485283 Up 0.109838655 Efhc2 EF-hand domain (C-terminal) containing 2 - - GO:0046872//metal ion binding - gi|262050574|ref|NP_083192.2|/0/EF-hand domain-containing family member C2 [Mus musculus] 414081 3631 0.053333333 0.073333333 0.459431619 Up 0.109838655 5330413P13Rik RIKEN cDNA 5330413P13 gene - - - - - 73072 4657 0.083333333 0.06 -0.473931188 Down 0.109838655 Prr36 proline rich 36 K14000|1|2e-10|72.0|tru:101065193|ribosome-binding protein 1;K19941|3|4e-09|67.4|mdo:100017646|synapsin;K16882|4|7e-09|66.6|lve:103085058|protein piccolo;K13908|5|2e-08|65.1|mcc:720912|mucin-5B - - - gi|161016770|ref|NP_997086.2|/0/putative uncharacterized protein FLJ22184 [Mus musculus] 223838 6119 0.076666667 0.056666667 -0.436099115 Down 0.109838655 Adamts20 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20" K09609|1|0.0|1012|mmu:223838|a disintegrin and metalloproteinase with thrombospondin motifs 20 [EC:3.4.24.-] - - - gi|259155423|ref|NP_001158258.1|/0/A disintegrin and metalloproteinase with thrombospondin motifs 20 isoform 3 precursor [Mus musculus] 26971 2437 0.063333333 0.046666667 -0.440572591 Down 0.109838655 Pla2g2f "phospholipase A2, group IIF" K01047|1|5e-116|421|mmu:26971|secretory phospholipase A2 [EC:3.1.1.4] - GO:0046872//metal ion binding;GO:0003824//catalytic activity GO:0006796//phosphate-containing compound metabolic process;GO:0006629//lipid metabolic process gi|672054638|ref|XP_008762511.1|/1.18853e-120/PREDICTED: group IIF secretory phospholipase A2 isoform X1 [Rattus norvegicus] 77531 7121.9 0.076666667 0.056666667 -0.436099115 Down 0.109838655 Anks1b ankyrin repeat and sterile alpha motif domain containing 1B K11322|1|6e-12|77.4|api:100158774|enhancer of polycomb-like protein;K12474|2|2e-08|65.9|shr:100934252|low density lipoprotein receptor adapter protein 1;K06057|3|2e-08|65.9|oas:101120009|numb;K12475|4|2e-08|65.5|xma:102218895|disabled homolog 2 GO:0044327//dendritic spine head;GO:0016604//nuclear body;GO:0097060//synaptic membrane;GO:0044327//dendritic spine head;GO:0016604//nuclear body;GO:0097060//synaptic membrane GO:0005102//receptor binding;GO:0005102//receptor binding - gi|294345388|ref|NP_001121558.2|/0/ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform 1 [Mus musculus] 18193 12784 4.75 4.84 0.027079534 Up 0.109688217 Nsd1 nuclear receptor-binding SET-domain protein 1 K15588|1|0.0|5237|mmu:18193|histone-lysine N-methyltransferase NSD1 [EC:2.1.1.43] - - - "gi|118918400|ref|NP_032765.3|/0/histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific [Mus musculus] " 100855 4316.07 4.136666667 4.05 -0.030546802 Down 0.109688217 Tbc1d14 "TBC1 domain family, member 14" K20167|1|0.0|840|mmu:100855|TBC1 domain family member 14 GO:0005773//vacuole;GO:0005773//vacuole;GO:0005773//vacuole GO:0019900//kinase binding;GO:0019900//kinase binding;GO:0019900//kinase binding GO:0000045//autophagosome assembly;GO:0000045//autophagosome assembly;GO:0000045//autophagosome assembly gi|164565375|ref|NP_001106833.1|/0/TBC1 domain family member 14 isoform a [Mus musculus] 74326 7901.85 4.313333333 4.226666667 -0.029282872 Down 0.109688217 Hnrnpr heterogeneous nuclear ribonucleoprotein R K13161|1|0.0|719|ecb:100071619|heterogeneous nuclear ribonucleoprotein R - - - - 268880 3111 4.286666667 4.373333333 0.028877077 Up 0.109688217 Xxylt1 xyloside xylosyltransferase 1 K09668|1|2e-14|84.7|cge:100750932|glycosyltransferase-like protein LARGE - - - gi|74178412|dbj|BAE32468.1|/0/unnamed protein product [Mus musculus] 16210 3432 4.176666667 4.09 -0.030251166 Down 0.109688217 Impact "impact, RWD domain protein" K11971|1|2e-06|58.2|tru:101076972|E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.27] - GO:0005488//binding GO:0006413//translational initiation gi|10863157|gb|AAG23916.1|/5.81222e-156/imprinted and ancient [Mus musculus] 192232 2852 4.016666667 4.11 0.033139653 Up 0.109688217 Hps4 Hermansky-Pudlak syndrome 4 K20194|1|0.0|1264|mmu:192232|Hermansky-Pudlak syndrome 4 protein - - - - 69606 2042 4.466666667 4.376666667 -0.029366084 Down 0.109688217 Mtfmt mitochondrial methionyl-tRNA formyltransferase K00604|1|0.0|771|mmu:69606|methionyl-tRNA formyltransferase [EC:2.1.2.9] GO:0043231//intracellular membrane-bounded organelle GO:0016741 - "gi|148694146|gb|EDL26093.1|/0/mitochondrial methionyl-tRNA formyltransferase, isoform CRA_a [Mus musculus]" 72587 4628 4.613333333 4.526666667 -0.027360463 Down 0.109688217 Pan3 PAN3 poly(A) specific ribonuclease subunit K12572|1|0.0|1422|mmu:72587|PAB-dependent poly(A)-specific ribonuclease subunit 3 - - - gi|270265830|ref|NP_082567.3|/0/PAB-dependent poly(A)-specific ribonuclease subunit PAN3 [Mus musculus] 109689 7097.13 5.193333333 5.103333333 -0.025220951 Down 0.109688217 Arrb1 "arrestin, beta 1" K04439|1|0.0|665|mmu:109689|beta-arrestin GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0097060//synaptic membrane;GO:0044327//dendritic spine head;GO:0044427;GO:0012506//vesicle membrane;GO:0005764//lysosome;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0097060//synaptic membrane;GO:0044327//dendritic spine head;GO:0044427;GO:0012506//vesicle membrane;GO:0005764//lysosome "GO:0019901//protein kinase binding;GO:0030674//protein binding, bridging;GO:0032403//protein complex binding;GO:0035258//steroid hormone receptor binding;GO:0051219//phosphoprotein binding;GO:0031893;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0008047//enzyme activator activity;GO:0031690//adrenergic receptor binding;GO:0008080//N-acetyltransferase activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0000975//regulatory region DNA binding;GO:0019901//protein kinase binding;GO:0030674//protein binding, bridging;GO:0032403//protein complex binding;GO:0035258//steroid hormone receptor binding;GO:0051219//phosphoprotein binding;GO:0031893;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0008047//enzyme activator activity;GO:0031690//adrenergic receptor binding;GO:0008080//N-acetyltransferase activity;GO:0044389//ubiquitin-like protein ligase binding;GO:0000975//regulatory region DNA binding" "GO:0048193//Golgi vesicle transport;GO:0001934//positive regulation of protein phosphorylation;GO:0001541//ovarian follicle development;GO:0016567//protein ubiquitination;GO:0035066//positive regulation of histone acetylation;GO:0007266//Rho protein signal transduction;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0006198//cAMP catabolic process;GO:0001775//cell activation;GO:0001818//negative regulation of cytokine production;GO:0032024//positive regulation of insulin secretion;GO:0006171//cAMP biosynthetic process;GO:0043087//regulation of GTPase activity;GO:0050954//sensory perception of mechanical stimulus;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0043393//regulation of protein binding;GO:0010661;GO:0045184//establishment of protein localization;GO:0043410//positive regulation of MAPK cascade;GO:0051017//actin filament bundle assembly;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0006366//transcription from RNA polymerase II promoter;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007599//hemostasis;GO:0048193//Golgi vesicle transport;GO:0001934//positive regulation of protein phosphorylation;GO:0001541//ovarian follicle development;GO:0016567//protein ubiquitination;GO:0035066//positive regulation of histone acetylation;GO:0007266//Rho protein signal transduction;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0006198//cAMP catabolic process;GO:0001775//cell activation;GO:0001818//negative regulation of cytokine production;GO:0032024//positive regulation of insulin secretion;GO:0006171//cAMP biosynthetic process;GO:0043087//regulation of GTPase activity;GO:0050954//sensory perception of mechanical stimulus;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0043393//regulation of protein binding;GO:0010661;GO:0045184//establishment of protein localization;GO:0043410//positive regulation of MAPK cascade;GO:0051017//actin filament bundle assembly;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0006366//transcription from RNA polymerase II promoter;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007599//hemostasis" gi|30089688|ref|NP_835738.1|/0/beta-arrestin-1 isoform B [Mus musculus] 226539 3621 4.896666667 4.81 -0.025763096 Down 0.109688217 Dars2 aspartyl-tRNA synthetase 2 (mitochondrial) K01876|1|0.0|1310|mmu:226539|aspartyl-tRNA synthetase [EC:6.1.1.12] GO:0044429 GO:0032550;GO:0042802//identical protein binding;GO:0004812//aminoacyl-tRNA ligase activity GO:0006412//translation;GO:0006399//tRNA metabolic process "gi|27369928|ref|NP_766232.1|/0/aspartate--tRNA ligase, mitochondrial precursor [Mus musculus]" 217882 6640 4.056666667 3.966666667 -0.032367595 Down 0.109688217 Cep170b centrosomal protein 170B K16463|1|0.0|2736|mmu:217882|centrosomal protein CEP170 - - - gi|28972129|dbj|BAC65518.1|/0/mKIAA0284 protein [Mus musculus] 16336 587 4.713333333 4.62 -0.028854863 Down 0.109688217 Insl3 insulin-like 3 K05255|1|2e-58|227|mmu:16336|relaxin GO:0044421;GO:0044444//cytoplasmic part GO:0005102//receptor binding;GO:0019899//enzyme binding GO:0008283//cell proliferation;GO:0008406//gonad development;GO:0006915//apoptotic process;GO:0043009//chordate embryonic development;GO:0006171//cAMP biosynthetic process;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway gi|56119092|ref|NP_038592.3|/1.17132e-57/insulin-like 3 precursor [Mus musculus] 59079 6460.23 4.363333333 4.453333333 0.029454911 Up 0.109688217 Erbb2ip Erbb2 interacting protein K12796|1|0.0|2637|mmu:59079|erbb2-interacting protein GO:0030055//cell-substrate junction;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0030055//cell-substrate junction;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0030055//cell-substrate junction;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0030055//cell-substrate junction;GO:0044459;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0006886//intracellular protein transport;GO:0006886//intracellular protein transport;GO:0006886//intracellular protein transport;GO:0006886//intracellular protein transport gi|575403049|ref|NP_001276403.1|/0/protein LAP2 isoform 4 [Mus musculus] 100503790 1619 4.173333333 4.083333333 -0.031452813 Down 0.109688217 Gm19897 "predicted gene, 19897" K11412|1|5e-13|78.6|mmu:64383|NAD-dependent deacetylase sirtuin 2 [EC:3.5.1.-] - - - - 67064 2529 10.68 10.83666667 0.021009408 Up 0.109584791 Chmp1b charged multivesicular body protein 1B K12197|1|5e-83|311|mmu:67064|charged multivesicular body protein 1 - - - - 12496 1937 9.96 10.12333333 0.02346676 Up 0.109584791 Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 K01509|1|0.0|920|mmu:12496|adenosinetriphosphatase [EC:3.6.1.3] GO:0031224//intrinsic component of membrane;GO:0005604//basement membrane GO:0032550;GO:0016462//pyrophosphatase activity GO:0001775//cell activation;GO:0009137;GO:0007166//cell surface receptor signaling pathway gi|161484610|ref|NP_033979.2|/0/ectonucleoside triphosphate diphosphohydrolase 2 precursor [Mus musculus] 19261 3884.44 10.01333333 9.856666667 -0.022750569 Down 0.109584791 Sirpa signal-regulatory protein alpha K06551|1|9e-54|214|mmu:19261|signal-regulatory protein alpha/beta1/gamma GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0051219//phosphoprotein binding;GO:0019904//protein domain specific binding;GO:0051219//phosphoprotein binding;GO:0019904//protein domain specific binding;GO:0051219//phosphoprotein binding;GO:0019904//protein domain specific binding;GO:0051219//phosphoprotein binding;GO:0019904//protein domain specific binding;GO:0051219//phosphoprotein binding;GO:0019904//protein domain specific binding;GO:0051219//phosphoprotein binding GO:0006909//phagocytosis;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0031589//cell-substrate adhesion;GO:0006909//phagocytosis;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0031589//cell-substrate adhesion;GO:0006909//phagocytosis;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0031589//cell-substrate adhesion;GO:0006909//phagocytosis;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0031589//cell-substrate adhesion;GO:0006909//phagocytosis;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0031589//cell-substrate adhesion;GO:0006909//phagocytosis;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0031589//cell-substrate adhesion gi|597436921|ref|NP_001277950.1|/4.15073e-130/tyrosine-protein phosphatase non-receptor type substrate 1 isoform 4 precursor [Mus musculus] 77573 4114 10.76 10.6 -0.021613813 Down 0.109584791 Vps33a VPS33A CORVET/HOPS core subunit K20182|1|0.0|1122|mmu:77573|vacuolar protein sorting-associated protein 33 GO:0005764//lysosome;GO:0005774//vacuolar membrane;GO:0031982//vesicle;GO:0005770//late endosome GO:0005515//protein binding GO:0012502//induction of programmed cell death;GO:0048066//developmental pigmentation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0006915//apoptotic process;GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0051875//pigment granule localization gi|254588041|ref|NP_084205.3|/0/vacuolar protein sorting-associated protein 33A [Mus musculus] 16773 9734 10.64333333 10.48666667 -0.021393882 Down 0.109584791 Lama2 "laminin, alpha 2" "K05637|1|0.0|6245|mmu:16773|laminin, alpha 1/2" GO:0043256//laminin complex;GO:0030425//dendrite;GO:0005886//plasma membrane - "GO:0016477//cell migration;GO:0006935//chemotaxis;GO:0007271//synaptic transmission, cholinergic;GO:0007155//cell adhesion;GO:0009790//embryo development" gi|117647249|ref|NP_032507.2|/0/laminin subunit alpha-2 precursor [Mus musculus] 66049 1392 15.08666667 15.25 0.015535159 Up 0.109584791 Rogdi rogdi homolog K16938|1|2e-116|421|cge:100771793|septin 3/9/12;K19367|2|9e-18|94.0|hro:HELRODRAFT_190950|maspardin GO:0012505//endomembrane system - GO:0008283//cell proliferation;GO:0048534//hematopoietic or lymphoid organ development "gi|148664857|gb|EDK97273.1|/8.84557e-154/rogdi homolog (Drosophila), isoform CRA_b, partial [Mus musculus]" 70083 1363 15.05333333 14.89 -0.015739231 Down 0.109584791 Metrn "meteorin, glial cell differentiation regulator" K00901|1|2e-34|149|bfo:BRAFLDRAFT_118688|diacylglycerol kinase (ATP) [EC:2.7.1.107] GO:0044421 - GO:0007409//axonogenesis "gi|14250503|gb|AAH08695.1|/1.08762e-156/Metrn protein, partial [Mus musculus]" 319263 5235 9.43 9.593333333 0.024774415 Up 0.109584791 Pcmtd1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 K00573|1|8e-16|89.7|tca:659715|protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] GO:0044424 GO:0008757//S-adenosylmethionine-dependent methyltransferase activity GO:0036211//protein modification process gi|411146649|ref|NP_001244274.1|/6.16092e-176/protein-L-isoaspartate O-methyltransferase domain-containing protein 1 [Rattus norvegicus] 27224 4592 13.62 13.46 -0.017048293 Down 0.109584791 Tceb3 "transcription elongation factor B (SIII), polypeptide 3" "K15076|1|0.0|1319|mmu:27224|transcription elongation factor B, polypeptide 3" GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0031981//nuclear lumen "GO:0008135//translation factor activity, RNA binding;GO:0043566//structure-specific DNA binding" GO:0044764;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006366//transcription from RNA polymerase II promoter gi|31543847|ref|NP_038764.2|/0/transcription elongation factor B polypeptide 3 [Mus musculus] 67148 1423 14.29 14.12666667 -0.016584829 Down 0.109584791 Fam103a1 "family with sequence similarity 103, member A1" K18708|1|2e-51|205|mmu:67148|RNMT-activating mini protein GO:0034518//RNA cap binding complex;GO:0043231//intracellular membrane-bounded organelle - GO:0006370//7-methylguanosine mRNA capping gi|21313122|ref|NP_080273.1|/1.89482e-50/RNMT-activating mini protein [Mus musculus] 16939 1799 0.306666667 0.34 0.148863386 Up 0.109537779 Lor loricrin K10385|1|2e-06|56.6|ptr:737452|loricrin - - - gi|594055011|ref|XP_006051749.1|/3.79699e-09/PREDICTED: loricrin [Bubalus bubalis] 69640 4786 0.296666667 0.33 0.153623189 Up 0.109537779 Fam83g "family with sequence similarity 83, member G" K16805|1|4e-54|216|mdo:100032771|protein FAM83D - - - gi|117647255|ref|NP_848733.2|/0/protein FAM83G [Mus musculus] 74377 2867 0.296666667 0.266666667 -0.153805336 Down 0.109537779 Hsf2bp heat shock transcription factor 2 binding protein K16493|1|8e-36|155|ngi:103736091|protocadherin alpha GO:0044444//cytoplasmic part - GO:0050896//response to stimulus gi|254675341|ref|NP_083178.1|/3.73383e-177/heat shock factor 2-binding protein [Mus musculus] 215627 3288 0.336666667 0.303333333 -0.150416843 Down 0.109537779 Zbtb8b zinc finger and BTB domain containing 8b K10495|1|0.0|950|mmu:215627|zinc finger and BTB domain-containing protein 8 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|568928752|ref|XP_006502989.1|/0/PREDICTED: zinc finger and BTB domain-containing protein 8B isoform X1 [Mus musculus] 30806 4477 0.336666667 0.303333333 -0.150416843 Down 0.109537779 Adamts8 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8" K08623|1|0.0|1759|mmu:30806|a disintegrin and metalloproteinase with thrombospondin motifs 8 [EC:3.4.24.-] - - - - 100040766 7502 0.303333333 0.273333333 -0.150242636 Down 0.109537779 Mroh2a maestro heat-like repeat family member 2A - - - - gi|527317377|ref|NP_001268395.1|/0/maestro heat-like repeat-containing protein family member 2A [Mus musculus] 101565 5024 0.34 0.306666667 -0.148863386 Down 0.109537779 Ccp110 centriolar coiled coil protein 110 K16453|1|0.0|1813|mmu:101565|centrosomal protein CEP110 - - - - 22355 3403 0.663333333 0.706666667 0.091295834 Up 0.109500169 Vipr2 vasoactive intestinal peptide receptor 2 K04590|1|0.0|902|mmu:22355|vasoactive intestinal peptide receptor 2 GO:0031224//intrinsic component of membrane GO:0004930//G-protein coupled receptor activity GO:0008285//negative regulation of cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0045762//positive regulation of adenylate cyclase activity gi|6678575|ref|NP_033537.1|/0/vasoactive intestinal polypeptide receptor 2 precursor [Mus musculus] 100233208 4747 0.573333333 0.61 0.089435084 Up 0.109500169 Gm10778 predicted gene 10778 K09228|1|0.0|1100|mmu:100233208|KRAB domain-containing zinc finger protein GO:0044464 GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" "gi|34785742|gb|AAH57364.1|/0/EG210583 protein, partial [Mus musculus]" 213556 6886 0.743333333 0.7 -0.086654382 Down 0.109500169 Plekhh2 "pleckstrin homology domain containing, family H (with MyTH4 domain) member 2" "K10417|1|2e-73|281|bom:102275591|dynein light intermediate chain 2, cytosolic;K12559|2|4e-33|147|nve:NEMVE_v1g162932|myosin X;K10359|3|8e-33|146|aqu:100639733|myosin VII" GO:0031224//intrinsic component of membrane;GO:0031252//cell leading edge;GO:0043232 GO:0008289//lipid binding - gi|188497685|ref|NP_808274.2|/0/pleckstrin homology domain-containing family H member 2 [Mus musculus] 234912 1592 0.59 0.553333333 -0.092566119 Down 0.109500169 9230110C19Rik RIKEN cDNA 9230110C19 gene - - - - gi|39841033|ref|NP_950182.1|/4.78428e-154/uncharacterized protein C11orf70 homolog [Mus musculus] 224440 1827 0.586666667 0.623333333 0.087462841 Up 0.109500169 Setd4 SET domain containing 4 K19199|1|4e-21|105|obi:106881421|histone-lysine N-methyltransferase SETD3 [EC:2.1.1.43] - - - gi|172073177|ref|NP_663457.2|/0/SET domain-containing protein 4 [Mus musculus] 234366 5077.45 11.76666667 11.92 0.018678553 Up 0.10903005 Gatad2a GATA zinc finger domain containing 2A K10310|1|2e-19|102|nvi:100122742|F-box protein 33 GO:0000118//histone deacetylase complex;GO:0000118//histone deacetylase complex;GO:0000118//histone deacetylase complex GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding "GO:0008219//cell death;GO:0016331//morphogenesis of embryonic epithelium;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0043009//chordate embryonic development;GO:0010171//body morphogenesis;GO:0001944//vasculature development;GO:0006351//transcription, DNA-templated;GO:0008219//cell death;GO:0016331//morphogenesis of embryonic epithelium;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0043009//chordate embryonic development;GO:0010171//body morphogenesis;GO:0001944//vasculature development;GO:0006351//transcription, DNA-templated;GO:0008219//cell death;GO:0016331//morphogenesis of embryonic epithelium;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0043009//chordate embryonic development;GO:0010171//body morphogenesis;GO:0001944//vasculature development;GO:0006351//transcription, DNA-templated" "gi|148696823|gb|EDL28770.1|/0/GATA zinc finger domain containing 2A, isoform CRA_a, partial [Mus musculus]" 67484 2689 9.263333333 9.116666667 -0.023025002 Down 0.10903005 Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 K10260|1|3e-06|57.0|bfo:BRAFLDRAFT_63751|F-box and WD-40 domain protein 7 - - GO:0006259//DNA metabolic process gi|50511063|dbj|BAD32517.1|/0/mKIAA1706 protein [Mus musculus] 329154 6156 1.173333333 1.223333333 0.060204634 Up 0.10903005 Ankrd44 ankyrin repeat domain 44 K15503|1|0.0|2001|mmu:329154|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B - GO:0005488//binding - gi|304376297|ref|NP_001074902.2|/0/serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B [Mus musculus] 12293 7400.01 12.17666667 12.03 -0.01748261 Down 0.10903005 Cacna2d1 "calcium channel, voltage-dependent, alpha2/delta subunit 1" K04858|1|0.0|2140|rno:25399|voltage-dependent calcium channel alpha-2/delta-1 GO:0034704//calcium channel complex;GO:0042383//sarcolemma;GO:0005783//endoplasmic reticulum;GO:0034704//calcium channel complex;GO:0042383//sarcolemma;GO:0005783//endoplasmic reticulum;GO:0034704//calcium channel complex;GO:0042383//sarcolemma;GO:0005783//endoplasmic reticulum;GO:0034704//calcium channel complex;GO:0042383//sarcolemma;GO:0005783//endoplasmic reticulum;GO:0034704//calcium channel complex;GO:0042383//sarcolemma;GO:0005783//endoplasmic reticulum GO:0043169//cation binding;GO:0005262//calcium channel activity;GO:0043169//cation binding;GO:0005262//calcium channel activity;GO:0043169//cation binding;GO:0005262//calcium channel activity;GO:0043169//cation binding;GO:0005262//calcium channel activity;GO:0043169//cation binding;GO:0005262//calcium channel activity GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport gi|161086896|ref|NP_001104313.1|/0/voltage-dependent calcium channel subunit alpha-2/delta-1 isoform a preproprotein [Mus musculus] 78246 1941.67 13.40666667 13.56 0.016406598 Up 0.10903005 Phf23 PHD finger protein 23 "K06158|1|3e-21|106|fch:102049818|ATP-binding cassette, subfamily F, member 3" - GO:0046872//metal ion binding - gi|987941535|ref|XP_006761686.2|/1.17665e-155/PREDICTED: PHD finger protein 23 [Myotis davidii] 225289 5375 1.09 1.136666667 0.060481104 Up 0.10903005 AW554918 expressed sequence AW554918 "K17563|1|6e-08|63.5|ocu:100347311|coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial" - - - gi|169234750|ref|NP_001028704.2|/0/protein hinderin [Mus musculus] 18080 8915.09 1.166666667 1.22 0.064488726 Up 0.10903005 Nin ninein K16476|1|0.0|3450|mmu:18080|ninein GO:0005813//centrosome GO:0005488//binding GO:0051640//organelle localization;GO:0000226//microtubule cytoskeleton organization "gi|148704640|gb|EDL36587.1|/0/ninein, isoform CRA_b, partial [Mus musculus]" 170776 1569 1.286666667 1.233333333 -0.061075577 Down 0.10903005 Cd209c CD209c antigen K06563|1|5e-108|394|mmu:170776|CD209 antigen - GO:0043169//cation binding - gi|18777733|ref|NP_570973.1|/4.29619e-107/CD209 antigen-like protein C [Mus musculus] 66461 1322 13.10666667 12.95333333 -0.016977421 Down 0.10903005 Ptpmt1 "protein tyrosine phosphatase, mitochondrial 1" K14165|1|6e-149|529|mmu:66461|atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] - - - gi|23956130|ref|NP_079852.1|/5.18197e-148/phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [Mus musculus] 229055 7464 1.146666667 1.196666667 0.061575279 Up 0.10903005 Zbtb10 zinc finger and BTB domain containing 10 K10497|1|0.0|1398|mmu:229055|zinc finger and BTB domain-containing protein 10 - GO:0005488//binding "GO:0006351//transcription, DNA-templated" gi|242397505|ref|NP_808328.2|/0/zinc finger and BTB domain-containing protein 10 [Mus musculus] 14236 5101 1.15 1.2 0.061400545 Up 0.10903005 Foxn2 forkhead box N2 K09407|1|0.0|818|mmu:14236|forkhead box protein N - - - gi|163965351|ref|NP_851305.2|/0/forkhead box protein N2 [Mus musculus] 80902 3877 1.2 1.246666667 0.055041364 Up 0.10903005 Zfp202 zinc finger protein 202 K09229|1|0.0|1341|mmu:80902|KRAB and SCAN domains-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0044764;GO:0006351//transcription, DNA-templated" gi|257796269|ref|NP_109638.2|/0/zinc finger protein 202 [Mus musculus] 140780 6585 1.076666667 1.123333333 0.061214426 Up 0.10903005 Bmp2k BMP2 inducible kinase K08854|1|0.0|970|mmu:140780|BMP2 inducible kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004672//protein kinase activity;GO:0030234//enzyme regulator activity GO:0019222//regulation of metabolic process;GO:0006464//cellular protein modification process;GO:0030278//regulation of ossification;GO:0006796//phosphate-containing compound metabolic process gi|18129622|ref|NP_542439.1|/0/BMP-2-inducible protein kinase [Mus musculus] 75841 4348 10.81333333 10.66 -0.020603881 Down 0.10903005 Rnf139 ring finger protein 139 K15703|1|0.0|1301|mmu:75841|E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0006412//translation;GO:0016567//protein ubiquitination;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0016485//protein processing;GO:0008283//cell proliferation gi|30424858|ref|NP_780435.1|/0/E3 ubiquitin-protein ligase RNF139 [Mus musculus] 77963 4252 1.176666667 1.23 0.063952633 Up 0.10903005 Hook1 hook microtubule tethering protein 1 K16612|1|0.0|1246|mmu:77963|protein HOOK1 - - - - 14586 3487 1.103333333 1.056666667 -0.062348377 Down 0.10903005 Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 K19895|1|3e-120|436|cmk:103188960|GDNF family receptor alpha 1 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004896//cytokine receptor activity;GO:0004896//cytokine receptor activity;GO:0004896//cytokine receptor activity GO:0048731//system development;GO:0001933//negative regulation of protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048731//system development;GO:0001933//negative regulation of protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048731//system development;GO:0001933//negative regulation of protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway "gi|148703928|gb|EDL35875.1|/0/glial cell line derived neurotrophic factor family receptor alpha 2, isoform CRA_a, partial [Mus musculus]" 54698 1936 0.053333333 0.07 0.392317423 Up 0.10899244 Crtam cytotoxic and regulatory T cell molecule K16361|1|4e-175|617|mmu:54698|cytotoxic and regulatory T-cell molecule GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0005515//protein binding;GO:0005515//protein binding GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0050663//cytokine secretion;GO:0002420;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0050663//cytokine secretion;GO:0002420 gi|530339637|ref|NP_001268883.1|/8.28734e-175/cytotoxic and regulatory T-cell molecule isoform 1 precursor [Mus musculus] 71908 1851 0.106666667 0.083333333 -0.35614381 Down 0.10899244 Cldn23 claudin 23 K06087|1|2e-138|495|mmu:71908|claudin - - - - 15484 1874 0.083333333 0.106666667 0.35614381 Up 0.10899244 Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 K00071|1|0.0|674|mmu:15484|corticosteroid 11-beta-dehydrogenase isozyme 2 [EC:1.1.1.-] GO:0043231//intracellular membrane-bounded organelle "GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0008289//lipid binding;GO:0000166//nucleotide binding" GO:0044703;GO:0001977;GO:0031667//response to nutrient levels;GO:0043434//response to peptide hormone;GO:0031960//response to corticosteroid;GO:0008202//steroid metabolic process gi|133778913|ref|NP_032315.2|/0/corticosteroid 11-beta-dehydrogenase isozyme 2 [Mus musculus] 12316 9866 0.09 0.07 -0.362570079 Down 0.10899244 Aspm "asp (abnormal spindle)-like, microcephaly associated (Drosophila)" K16743|1|0.0|5996|mmu:12316|abnormal spindle-like microcephaly-associated protein - - - gi|87298845|ref|NP_033921.3|/0/abnormal spindle-like microcephaly-associated protein homolog [Mus musculus] 269589 1940 0.056666667 0.073333333 0.371968777 Up 0.10899244 Sytl1 synaptotagmin-like 1 K17598|1|0.0|931|mmu:269589|synaptotagmin-like protein - - - - 327743 1418 0.073333333 0.096666667 0.398549376 Up 0.10899244 Wisp3 WNT1 inducible signaling pathway protein 3 K06827|1|6e-68|260|xma:102235918|connective tissue growth factor GO:0044421 GO:0019838//growth factor binding;GO:0005102//receptor binding GO:0016049//cell growth;GO:0007154//cell communication gi|188497673|ref|NP_001120848.1|/0/WNT1-inducible-signaling pathway protein 3 precursor [Mus musculus] 547347 1633 0.066666667 0.086666667 0.378511623 Up 0.10899244 Gm6034 predicted gene 6034 "K06751|1|2e-51|120|cge:100753528|major histocompatibility complex, class I" - - - gi|294661840|ref|NP_001030081.2|/1.21649e-51/H2-GS14-2 antigen [Mus musculus] 319469 3154 0.08 0.103333333 0.36923381 Up 0.10899244 A230056J06Rik RIKEN cDNA A230056J06 gene - - - - gi|148709333|gb|EDL41279.1|/7.93059e-27/mCG148433 [Mus musculus] 68891 2733 0.053333333 0.07 0.392317423 Up 0.10899244 Cd177 CD177 antigen K06552|1|0.0|1627|mmu:68891|CD177 antigen GO:0031224//intrinsic component of membrane - - gi|34328436|ref|NP_081138.2|/0/CD177 antigen precursor [Mus musculus] 12630 2073 0.073333333 0.096666667 0.398549376 Up 0.10899244 Cfi complement component factor i K01333|1|0.0|1224|mmu:12630|complement factor I [EC:3.4.21.45] GO:0044421 GO:0004175//endopeptidase activity;GO:0043169//cation binding;GO:0038024//cargo receptor activity GO:0019538//protein metabolic process;GO:0006952//defense response;GO:0002455//humoral immune response mediated by circulating immunoglobulin gi|110347406|ref|NP_031712.2|/0/complement factor I precursor [Mus musculus] 70377 1336 0.08 0.103333333 0.36923381 Up 0.10899244 Derl3 "Der1-like domain family, member 3" K13989|1|8e-88|326|mmu:70377|Derlin-2/3 GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0005488//binding GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006984//ER-nucleus signaling pathway;GO:0006487//protein N-linked glycosylation gi|568968466|ref|XP_006514142.1|/8.55108e-90/PREDICTED: derlin-3 isoform X1 [Mus musculus] 192190 12750 0.096666667 0.073333333 -0.398549376 Down 0.10899244 Pkhd1l1 polycystic kidney and hepatic disease 1-like 1 K19865|1|0.0|788|cmy:102931988|fibrocystin - - - - 211147 1391 0.076666667 0.1 0.38332864 Up 0.10899244 11-Mar membrane-associated ring finger (C3HC4) 11 K10659|1|0.0|689|mmu:211147|E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27] - - - gi|193794868|ref|NP_808265.2|/0/E3 ubiquitin-protein ligase MARCH11 isoform 1 [Mus musculus] 73472 1949 0.103333333 0.08 -0.36923381 Down 0.10899244 Spata18 spermatogenesis associated 18 - GO:0031966//mitochondrial membrane;GO:0005930//axoneme - GO:0048869//cellular developmental process;GO:0000422//mitophagy;GO:0033554//cellular response to stress;GO:0048232//male gamete generation;GO:0007005//mitochondrion organization gi|226442916|ref|NP_848474.2|/0/mitochondria-eating protein [Mus musculus] 16492 4844 0.073333333 0.056666667 -0.371968777 Down 0.10899244 Kcna4 "potassium voltage-gated channel, shaker-related subfamily, member 4" K04877|1|0.0|946|mmu:16492|potassium voltage-gated channel Shaker-related subfamily A member 4 - - - gi|31543026|ref|NP_067250.2|/0/potassium voltage-gated channel subfamily A member 4 [Mus musculus] 18413 1907 0.08 0.103333333 0.36923381 Up 0.10899244 Osm oncostatin M K05418|1|4e-97|358|mmu:18413|oncostatin M - - - - 21816 2755 0.076666667 0.1 0.38332864 Up 0.10899244 Tgm1 "transglutaminase 1, K polypeptide" K05619|1|0.0|1422|mmu:21816|transglutaminase 1 [EC:2.3.2.13] GO:0005911//cell-cell junction;GO:0044425;GO:0005911//cell-cell junction;GO:0044425;GO:0005911//cell-cell junction;GO:0044425 "GO:0043169//cation binding;GO:0016755//transferase activity, transferring amino-acyl groups;GO:0043169//cation binding;GO:0016755//transferase activity, transferring amino-acyl groups;GO:0043169//cation binding;GO:0016755//transferase activity, transferring amino-acyl groups" GO:0030216//keratinocyte differentiation;GO:0009653//anatomical structure morphogenesis;GO:0006464//cellular protein modification process;GO:0030216//keratinocyte differentiation;GO:0009653//anatomical structure morphogenesis;GO:0006464//cellular protein modification process;GO:0030216//keratinocyte differentiation;GO:0009653//anatomical structure morphogenesis;GO:0006464//cellular protein modification process gi|239787887|ref|NP_064368.3|/0/protein-glutamine gamma-glutamyltransferase K [Mus musculus] 245595 4330 0.056666667 0.073333333 0.371968777 Up 0.10899244 Zfp711 zinc finger protein 711 K09228|1|5e-65|253|sko:100371350|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated" gi|125347348|ref|NP_808415.2|/0/zinc finger protein 711 [Mus musculus] 210853 2659 0.263333333 0.29 0.139162748 Up 0.108682162 Zfp947 zinc finger protein 947 K09228|1|0.0|951|mmu:210853|KRAB domain-containing zinc finger protein - - - - 74365 7392 0.323333333 0.356666667 0.141554144 Up 0.108682162 Lonrf3 LON peptidase N-terminal domain and ring finger 3 K09553|1|5e-11|74.3|pxy:105381760|stress-induced-phosphoprotein 1 - "GO:0046914//transition metal ion binding;GO:0042623//ATPase activity, coupled" GO:0019538//protein metabolic process gi|71043955|ref|NP_083170.1|/0/LON peptidase N-terminal domain and RING finger protein 3 [Mus musculus] 100039863 712 0.28 0.253333333 -0.144389909 Down 0.108682162 Gm13306 predicted gene 13306 K16598|1|4e-44|178|mmu:100861978|C-C motif chemokine 27 - GO:0005125//cytokine activity;GO:0005125//cytokine activity;GO:0005125//cytokine activity GO:0002376//immune system process;GO:0002376//immune system process;GO:0002376//immune system process "gi|148673427|gb|EDL05374.1|/1.55485e-67/chemokine (C-C motif) ligand 27, isoform CRA_a [Mus musculus]" 235386 5103 0.32 0.29 -0.142019005 Down 0.108682162 Hykk hydroxylysine kinase 1 K18201|1|0.0|720|mmu:235386|hydroxylysine kinase [EC:2.7.1.81] - - - "gi|148693886|gb|EDL25833.1|/0/RIKEN cDNA C630028N24, isoform CRA_a [Mus musculus]" 381524 2033 0.283333333 0.256666667 -0.142604395 Down 0.108682162 AI427809 expressed sequence AI427809 - - - - "gi|148670335|gb|EDL02282.1|/1.63966e-46/mCG1041362, partial [Mus musculus]" 195046 4806 0.253333333 0.28 0.144389909 Up 0.108682162 Nlrp1a "NLR family, pyrin domain containing 1A" "K12798|1|0.0|2246|mmu:195046|NACHT, LRR and PYD domains-containing protein 1" - - - - 100039939 712 0.28 0.253333333 -0.144389909 Down 0.108682162 Gm2506 predicted gene 2506 K16598|1|1e-67|258|mmu:20301|C-C motif chemokine 27 - GO:0005125//cytokine activity;GO:0005125//cytokine activity GO:0002376//immune system process;GO:0002376//immune system process "gi|148673428|gb|EDL05375.1|/3.48808e-43/chemokine (C-C motif) ligand 27, isoform CRA_b [Mus musculus]" 100861978 712 0.28 0.253333333 -0.144389909 Down 0.108682162 LOC100861978 c-C motif chemokine 27-like K16598|1|4e-44|178|mmu:100861978|C-C motif chemokine 27 - GO:0005125//cytokine activity;GO:0005125//cytokine activity;GO:0005125//cytokine activity GO:0002376//immune system process;GO:0002376//immune system process;GO:0002376//immune system process "gi|148673427|gb|EDL05374.1|/1.55485e-67/chemokine (C-C motif) ligand 27, isoform CRA_a [Mus musculus]" 100040048 712 0.28 0.253333333 -0.144389909 Down 0.108682162 Ccl27b chemokine (C-C motif) ligand 27b K16598|1|4e-90|332|mmu:20301|C-C motif chemokine 27 - GO:0005125//cytokine activity;GO:0005125//cytokine activity;GO:0005125//cytokine activity GO:0002376//immune system process;GO:0002376//immune system process;GO:0002376//immune system process gi|114431222|ref|NP_001041644.1|/3.24633e-89/C-C motif chemokine 27 isoform 1 [Mus musculus] 209966 2854 0.29 0.32 0.142019005 Up 0.108682162 Pgbd5 piggyBac transposable element derived 5 "K00914|1|1e-13|81.6|tsp:Tsp_00889|phosphatidylinositol 3-kinase [EC:2.7.1.137];K05673|2|2e-07|60.8|cfo:105251729|ATP-binding cassette, subfamily C (CFTR/MRP), member 4" - - - gi|568956402|ref|XP_006530867.1|/0/PREDICTED: piggyBac transposable element-derived protein 5 isoform X1 [Mus musculus] 100502982 2009 0.27 0.296666667 0.135883428 Up 0.108682162 BC037704 cDNA sequence BC037704 - - - - - 80749 2584 0.08 0.063333333 -0.337034987 Down 0.108672759 Lrfn1 leucine rich repeat and fibronectin type III domain containing 1 K16354|1|0.0|797|mmu:80749|leucine-rich repeat and fibronectin type-III domain-containing protein 1 GO:0044327//dendritic spine head;GO:0031224//intrinsic component of membrane;GO:0097060//synaptic membrane;GO:0044327//dendritic spine head;GO:0031224//intrinsic component of membrane;GO:0097060//synaptic membrane - - gi|213512339|ref|NP_085039.2|/0/leucine-rich repeat and fibronectin type III domain-containing protein 1 isoform 2 precursor [Mus musculus] 404337 936 0.073333333 0.093333333 0.347923303 Up 0.108672759 Olfr1383 olfactory receptor 1383 K04257|1|7e-180|631|mmu:404337|olfactory receptor GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007608//sensory perception of smell gi|46430596|ref|NP_997457.1|/5.67326e-179/olfactory receptor 1383 [Mus musculus] 70887 1247 0.093333333 0.073333333 -0.347923303 Down 0.108672759 Dmrtc1a DMRT-like family C1a K19494|1|1e-89|271|mmu:70887|doublesex- and mab-3-related transcription factor 8 - - "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|269995936|ref|NP_001033705.2|/1.23557e-88/doublesex- and mab-3-related transcription factor C1 isoform c [Mus musculus] 319803 3687 0.08 0.063333333 -0.337034987 Down 0.108672759 A430090L17Rik RIKEN cDNA A430090L17 gene - - - - - 20614 2135 0.076666667 0.06 -0.353636955 Down 0.108672759 Snap25 synaptosomal-associated protein 25 K18211|1|4e-112|408|aam:106490461|synaptosomal-associated protein 25 GO:0043231//intracellular membrane-bounded organelle;GO:0030426//growth cone;GO:0044297//cell body;GO:0031252//cell leading edge;GO:0005856//cytoskeleton;GO:0031082;GO:0005887//integral component of plasma membrane;GO:0031201//SNARE complex;GO:0043231//intracellular membrane-bounded organelle;GO:0030426//growth cone;GO:0044297//cell body;GO:0031252//cell leading edge;GO:0005856//cytoskeleton;GO:0031082;GO:0005887//integral component of plasma membrane;GO:0031201//SNARE complex GO:0005267//potassium channel activity;GO:0008092//cytoskeletal protein binding;GO:0019905//syntaxin binding;GO:0005267//potassium channel activity;GO:0008092//cytoskeletal protein binding;GO:0019905//syntaxin binding GO:0015980//energy derivation by oxidation of organic compounds;GO:0007613//memory;GO:0006835//dicarboxylic acid transport;GO:0007269//neurotransmitter secretion;GO:0006904//vesicle docking involved in exocytosis;GO:0050796//regulation of insulin secretion;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007416//synapse assembly;GO:0015980//energy derivation by oxidation of organic compounds;GO:0007613//memory;GO:0006835//dicarboxylic acid transport;GO:0007269//neurotransmitter secretion;GO:0006904//vesicle docking involved in exocytosis;GO:0050796//regulation of insulin secretion;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007416//synapse assembly gi|537150989|gb|ERE71497.1|/2.18588e-115/synaptosomal-associated protein 25 [Cricetulus griseus] 19894 3918 0.066666667 0.083333333 0.321928095 Up 0.108672759 Rph3a rabphilin 3A K19938|1|0.0|1239|mmu:19894|rabphilin-3A GO:0032991//macromolecular complex;GO:0008021//synaptic vesicle;GO:0042995//cell projection;GO:0044425;GO:0032991//macromolecular complex;GO:0008021//synaptic vesicle;GO:0042995//cell projection;GO:0044425;GO:0032991//macromolecular complex;GO:0008021//synaptic vesicle;GO:0042995//cell projection;GO:0044425 GO:0043168//anion binding;GO:0017016//Ras GTPase binding;GO:0046914//transition metal ion binding;GO:0005543//phospholipid binding;GO:0043168//anion binding;GO:0017016//Ras GTPase binding;GO:0046914//transition metal ion binding;GO:0005543//phospholipid binding;GO:0043168//anion binding;GO:0017016//Ras GTPase binding;GO:0046914//transition metal ion binding;GO:0005543//phospholipid binding GO:0007417//central nervous system development;GO:0015031//protein transport;GO:0007417//central nervous system development;GO:0015031//protein transport;GO:0007417//central nervous system development;GO:0015031//protein transport gi|16945962|ref|NP_035416.1|/0/rabphilin-3A [Mus musculus] 69291 6017 0.08 0.1 0.321928095 Up 0.108672759 1700001L05Rik RIKEN cDNA 1700001L05 gene - - - - - 629499 3462 0.06 0.076666667 0.353636955 Up 0.108672759 Mroh8 maestro heat-like repeat family member 8 - - - - gi|160333434|ref|NP_001034646.2|/0/protein MROH8 [Mus musculus] 12836 9222 0.073333333 0.093333333 0.347923303 Up 0.108672759 Col7a1 "collagen, type VII, alpha 1" "K16628|1|0.0|2429|mmu:12836|collagen, type VII, alpha" - - - gi|568963457|ref|XP_006512000.1|/0/PREDICTED: collagen alpha-1(VII) chain isoform X3 [Mus musculus] 72647 1827 0.06 0.076666667 0.353636955 Up 0.108672759 2700089I24Rik RIKEN cDNA 2700089I24 gene - - - - - 67576 1950 0.076666667 0.096666667 0.334419039 Up 0.108672759 4930429B21Rik RIKEN cDNA 4930429B21 gene - - - - gi|148703041|gb|EDL34988.1|/4.26445e-70/RIKEN cDNA 4930429B21 [Mus musculus] 320707 6748 0.093333333 0.073333333 -0.347923303 Down 0.108672759 Atp2b3 "ATPase, Ca++ transporting, plasma membrane 3" "K05850|1|0.0|2122|ngi:103731188|Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]" GO:0031224//intrinsic component of membrane GO:0032550;GO:0003824//catalytic activity;GO:0019904//protein domain specific binding - "gi|148697949|gb|EDL29896.1|/0/ATPase, Ca++ transporting, plasma membrane 3, isoform CRA_b, partial [Mus musculus]" 102636083 1435 0.08 0.063333333 -0.337034987 Down 0.108672759 Mannr Mecom adjacent non-protein coding RNA - - - - - 140494 3300 0.083333333 0.066666667 -0.321928095 Down 0.108672759 Atp6v0a4 "ATPase, H+ transporting, lysosomal V0 subunit A4" K02154|1|0.0|1521|mmu:140494|V-type H+-transporting ATPase subunit a GO:0031224//intrinsic component of membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0005903//brush border;GO:0044459 GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0019899//enzyme binding "GO:0050954//sensory perception of mechanical stimulus;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0055067" gi|171543866|ref|NP_536715.3|/0/V-type proton ATPase 116 kDa subunit a isoform 4 [Mus musculus] 140810 11078 0.79 0.833333333 0.077041036 Up 0.108174433 Ttbk2 tau tubulin kinase 2 K08815|1|0.0|2242|mmu:140810|tau tubulin kinase [EC:2.7.11.26] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0004672//protein kinase activity;GO:0004672//protein kinase activity;GO:0004672//protein kinase activity GO:0006468//protein phosphorylation;GO:0006468//protein phosphorylation;GO:0006468//protein phosphorylation gi|67906805|ref|NP_542966.2|/0/tau-tubulin kinase 2 isoform 1 [Mus musculus] 98736 4362 0.663333333 0.626666667 -0.082035769 Down 0.108174433 1700034H15Rik RIKEN cDNA 1700034H15 gene "K14688|1|7e-39|166|rno:58976|solute carrier family 30 (zinc transporter), member 1" - - - - 66435 6514 0.716666667 0.676666667 -0.082856932 Down 0.108174433 Uggt2 UDP-glucose glycoprotein glucosyltransferase 2 K11718|1|0.0|2798|mmu:66435|UDP-glucose:glycoprotein glucosyltransferase [EC:2.4.1.-] - - - gi|158749642|ref|NP_001074721.2|/0/UDP-glucose:glycoprotein glucosyltransferase 2 precursor [Mus musculus] 330097 543 0.763333333 0.72 -0.084316286 Down 0.108174433 Gm5108 predicted gene 5108 - - - - gi|371874406|ref|NP_001243113.1|/4.25553e-50/uncharacterized protein LOC330097 [Mus musculus] 228876 5033 0.746666667 0.786666667 0.075288127 Up 0.108174433 Zfp334 zinc finger protein 334 K09228|1|0.0|1439|mmu:228876|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|162287397|ref|NP_848498.2|/0/zinc finger protein 334 [Mus musculus] 78610 3438 9.163333333 9.023333333 -0.022212019 Down 0.108127421 Uvrag UV radiation resistance associated gene "K01384|1|7e-21|105|tsp:Tsp_04250|wingless-type MMTV integration site family, member 11" GO:0005768//endosome;GO:0000323//lytic vacuole;GO:0032991//macromolecular complex GO:0019904//protein domain specific binding GO:0006259//DNA metabolic process;GO:0006914//autophagy gi|26335507|dbj|BAC31454.1|/0/unnamed protein product [Mus musculus] 106766 1574.5 12.2 12.33666667 0.016071487 Up 0.108127421 Stap2 signal transducing adaptor family member 2 - GO:0016020//membrane;GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0031981//nuclear lumen GO:0008289//lipid binding;GO:0008289//lipid binding - gi|22122357|ref|NP_666046.1|/0/signal-transducing adaptor protein 2 [Mus musculus] 677289 2245 9.123333333 8.983333333 -0.022310162 Down 0.108127421 Prr33 proline rich 33 - - - - - 99683 4702 9.136666667 9.276666667 0.021938581 Up 0.108127421 Sec24b "Sec24 related gene family, member B (S. cerevisiae)" K14007|1|0.0|2049|mmu:99683|protein transport protein SEC24 - - GO:0045184//establishment of protein localization gi|46402179|ref|NP_997092.1|/0/protein transport protein Sec24B [Mus musculus] 70047 2271.64 8.583333333 8.72 0.022790109 Up 0.108127421 Trnt1 "tRNA nucleotidyl transferase, CCA-adding, 1" K00974|1|3e-114|415|mmu:70047|tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0003723//RNA binding;GO:0070566//adenylyltransferase activity;GO:0032550;GO:0003723//RNA binding;GO:0070566//adenylyltransferase activity;GO:0032550;GO:0003723//RNA binding;GO:0070566//adenylyltransferase activity GO:0042780//tRNA 3'-end processing;GO:0042780//tRNA 3'-end processing;GO:0042780//tRNA 3'-end processing "gi|148666981|gb|EDK99397.1|/0/tRNA nucleotidyl transferase, CCA-adding, 1, isoform CRA_b, partial [Mus musculus]" 104725 1363 9.93 10.06666667 0.019720426 Up 0.108127421 Sptssa "serine palmitoyltransferase, small subunit A" - GO:0031211//endoplasmic reticulum palmitoyltransferase complex;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0016454//C-palmitoyltransferase activity GO:0006665//sphingolipid metabolic process gi|194038782|ref|XP_001926508.1|/7.81675e-30/PREDICTED: serine palmitoyltransferase small subunit A [Sus scrofa] 71365 1773 11.16 11.3 0.017985745 Up 0.108127421 Pdss2 "prenyl (solanesyl) diphosphate synthase, subunit 2" K12505|1|5e-167|590|mmu:71365|decaprenyl-diphosphate synthase subunit 2 [EC:2.5.1.91] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0046983//protein dimerization activity;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0046983//protein dimerization activity" GO:0006743//ubiquinone metabolic process;GO:0051262//protein tetramerization;GO:0006720//isoprenoid metabolic process;GO:0044707;GO:0006743//ubiquinone metabolic process;GO:0051262//protein tetramerization;GO:0006720//isoprenoid metabolic process;GO:0044707 gi|269973903|ref|NP_082048.2|/0/decaprenyl-diphosphate synthase subunit 2 isoform 1 [Mus musculus] 56095 2865 11.08666667 10.94666667 -0.018334042 Down 0.108127421 Ftsj3 FtsJ RNA methyltransferase homolog 3 (E. coli) K14857|1|0.0|1281|mmu:56095|AdoMet-dependent rRNA methyltransferase SPB1 [EC:2.1.1.-] - - - - 16331 4839.72 4.406666667 4.323333333 -0.027543697 Down 0.107939373 Inpp5d inositol polyphosphate-5-phosphatase D "K03084|1|0.0|1763|mmu:16331|phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]" GO:0016020//membrane;GO:0015629//actin cytoskeleton;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0015629//actin cytoskeleton;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0015629//actin cytoskeleton;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0015629//actin cytoskeleton;GO:0044444//cytoplasmic part GO:0046030//inositol trisphosphate phosphatase activity;GO:0016312//inositol bisphosphate phosphatase activity;GO:0019904//protein domain specific binding;GO:0052866//phosphatidylinositol phosphate phosphatase activity;GO:0046030//inositol trisphosphate phosphatase activity;GO:0016312//inositol bisphosphate phosphatase activity;GO:0019904//protein domain specific binding;GO:0052866//phosphatidylinositol phosphate phosphatase activity;GO:0046030//inositol trisphosphate phosphatase activity;GO:0016312//inositol bisphosphate phosphatase activity;GO:0019904//protein domain specific binding;GO:0052866//phosphatidylinositol phosphate phosphatase activity;GO:0046030//inositol trisphosphate phosphatase activity;GO:0016312//inositol bisphosphate phosphatase activity;GO:0019904//protein domain specific binding;GO:0052866//phosphatidylinositol phosphate phosphatase activity GO:0002683//negative regulation of immune system process;GO:0030223//neutrophil differentiation;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0030183//B cell differentiation;GO:0019724//B cell mediated immunity;GO:0010259//multicellular organism aging;GO:0006915//apoptotic process;GO:0030888//regulation of B cell proliferation;GO:0046488//phosphatidylinositol metabolic process;GO:0007165//signal transduction;GO:0030218//erythrocyte differentiation;GO:0032845;GO:0042036//negative regulation of cytokine biosynthetic process;GO:0002683//negative regulation of immune system process;GO:0030223//neutrophil differentiation;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0030183//B cell differentiation;GO:0019724//B cell mediated immunity;GO:0010259//multicellular organism aging;GO:0006915//apoptotic process;GO:0030888//regulation of B cell proliferation;GO:0046488//phosphatidylinositol metabolic process;GO:0007165//signal transduction;GO:0030218//erythrocyte differentiation;GO:0032845;GO:0042036//negative regulation of cytokine biosynthetic process;GO:0002683//negative regulation of immune system process;GO:0030223//neutrophil differentiation;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0030183//B cell differentiation;GO:0019724//B cell mediated immunity;GO:0010259//multicellular organism aging;GO:0006915//apoptotic process;GO:0030888//regulation of B cell proliferation;GO:0046488//phosphatidylinositol metabolic process;GO:0007165//signal transduction;GO:0030218//erythrocyte differentiation;GO:0032845;GO:0042036//negative regulation of cytokine biosynthetic process;GO:0002683//negative regulation of immune system process;GO:0030223//neutrophil differentiation;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0030183//B cell differentiation;GO:0019724//B cell mediated immunity;GO:0010259//multicellular organism aging;GO:0006915//apoptotic process;GO:0030888//regulation of B cell proliferation;GO:0046488//phosphatidylinositol metabolic process;GO:0007165//signal transduction;GO:0030218//erythrocyte differentiation;GO:0032845;GO:0042036//negative regulation of cytokine biosynthetic process "gi|148708208|gb|EDL40155.1|/0/inositol polyphosphate-5-phosphatase D, isoform CRA_g, partial [Mus musculus]" 12877 3123 4.516666667 4.436666667 -0.02578228 Down 0.107939373 Cpeb1 cytoplasmic polyadenylation element binding protein 1 K02602|1|0.0|1081|mmu:12877|cytoplasmic polyadenylation element-binding protein GO:0035770//ribonucleoprotein granule;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0005819//spindle;GO:0035770//ribonucleoprotein granule;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0005819//spindle;GO:0035770//ribonucleoprotein granule;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0005819//spindle GO:0003723//RNA binding;GO:0036094//small molecule binding;GO:0003723//RNA binding;GO:0036094//small molecule binding;GO:0003723//RNA binding;GO:0036094//small molecule binding GO:0006412//translation;GO:0006396//RNA processing;GO:0048167//regulation of synaptic plasticity;GO:0007129//synapsis;GO:0006412//translation;GO:0006396//RNA processing;GO:0048167//regulation of synaptic plasticity;GO:0007129//synapsis;GO:0006412//translation;GO:0006396//RNA processing;GO:0048167//regulation of synaptic plasticity;GO:0007129//synapsis gi|6681003|ref|NP_031781.1|/0/cytoplasmic polyadenylation element-binding protein 1 isoform 2 [Mus musculus] 69577 2362 3.266666667 3.343333333 0.033467952 Up 0.107939373 Fastkd3 FAST kinase domains 3 K08290|1|5e-22|108|ngi:103745309|Fas-activated serine/threonine kinase [EC:2.7.11.8] - GO:0016301//kinase activity - gi|568983598|ref|XP_006517427.1|/0/PREDICTED: FAST kinase domain-containing protein 3 isoform X2 [Mus musculus] 217203 2301 3.433333333 3.516666667 0.034598662 Up 0.107939373 Tmem106a transmembrane protein 106A - GO:0031224//intrinsic component of membrane - - gi|74204009|dbj|BAE29006.1|/1.93131e-155/unnamed protein product [Mus musculus] 97031 2825 4.54 4.456666667 -0.026727238 Down 0.107939373 Tprn taperin K17559|1|1e-20|105|cmy:102942334|phostensin GO:0005902//microvillus GO:0019899//enzyme binding GO:0050954//sensory perception of mechanical stimulus gi|190014629|ref|NP_780495.2|/0/taperin [Mus musculus] 105886298 844.61 4.653333333 4.57 -0.02607037 Down 0.107939373 Cmc4 C-x(9)-C motif containing 4 K16837|1|8e-26|120|fab:101807139|mature T-cell proliferation-1 type B1 - - - gi|6754760|ref|NP_034969.1|/6.63377e-33/cx9C motif-containing protein 4 [Mus musculus] 67973 2202 3.73 3.81 0.030615367 Up 0.107939373 Mphosph10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) K14559|1|0.0|946|mmu:67973|U3 small nucleolar RNA-associated protein MPP10 GO:0031981//nuclear lumen;GO:0030529//intracellular ribonucleoprotein complex GO:0005488//binding GO:0008380//RNA splicing;GO:0010921//regulation of phosphatase activity gi|68303650|ref|NP_080759.2|/0/U3 small nucleolar ribonucleoprotein protein MPP10 [Mus musculus] 231855 3817 3.54 3.616666667 0.030911277 Up 0.107939373 Ap5z1 "adaptor-related protein complex 5, zeta 1 subunit" K19025|1|0.0|1447|mmu:231855|AP-5 complex subunit zeta-1 GO:0043231//intracellular membrane-bounded organelle - GO:0044765//single-organism transport;GO:0006259//DNA metabolic process;GO:0045184//establishment of protein localization;GO:0033554//cellular response to stress gi|82546849|ref|NP_766313.2|/0/AP-5 complex subunit zeta-1 [Mus musculus] 108735 5526 4.756666667 4.673333333 -0.025498985 Down 0.107939373 Sft2d2 SFT2 domain containing 2 K10184|1|1e-38|165|fch:102055408|T-box protein 19 GO:0031224//intrinsic component of membrane - GO:0006810//transport;GO:0045184//establishment of protein localization gi|21704008|ref|NP_663487.1|/1.00214e-83/vesicle transport protein SFT2B [Mus musculus] 68262 1910 3.54 3.46 -0.032977322 Down 0.107939373 Agpat4 "1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)" K13523|1|0.0|795|mmu:68262|lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-] GO:0031224//intrinsic component of membrane GO:0016411//acylglycerol O-acyltransferase activity GO:0046341//CDP-diacylglycerol metabolic process gi|564325169|ref|XP_006227918.1|/0/PREDICTED: 1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X2 [Rattus norvegicus] 17764 7631 3.6 3.516666667 -0.033788313 Down 0.107939373 Mtf1 metal response element binding transcription factor 1 K09228|1|4e-40|171|ola:105355511|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0044212//transcription regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0019899//enzyme binding GO:0010038//response to metal ion;GO:0006950//response to stress;GO:0006366//transcription from RNA polymerase II promoter gi|188528620|ref|NP_032662.3|/0/metal regulatory transcription factor 1 [Mus musculus] 212986 3680 3.326666667 3.25 -0.033637597 Down 0.107939373 Scfd2 Sec1 family domain containing 2 - - - GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0045184//establishment of protein localization;GO:0006887//exocytosis gi|31982305|ref|NP_848787.2|/0/sec1 family domain-containing protein 2 isoform b [Mus musculus] 217304 2880 0.343333333 0.313333333 -0.131911676 Down 0.107704314 Cd300lb CD300 molecule like family member B K20395|1|5e-147|524|mmu:217304|CO300B/D/F antigen - - - - 24084 1500 0.33 0.36 0.125530882 Up 0.107704314 Tekt2 tektin 2 K18629|1|0.0|788|mmu:24084|tektin-2 GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton - GO:0048870//cell motility;GO:0016043//cellular component organization gi|148225693|ref|NP_036032.2|/0/tektin-2 [Mus musculus] 210104 3381 0.366666667 0.4 0.125530882 Up 0.107704314 Zfp658 zinc finger protein 658 K09228|1|0.0|1907|mmu:210104|KRAB domain-containing zinc finger protein - - - - 69434 542 0.386666667 0.353333333 -0.130060541 Down 0.107704314 Snhg10 small nucleolar RNA host gene 10 - - - - gi|148686828|gb|EDL18775.1|/9.03688e-29/mCG147636 [Mus musculus] 72608 782 0.356666667 0.39 0.128897733 Up 0.107704314 2700069I18Rik RIKEN cDNA 2700069I18 gene - - - - - 330463 4817.68 0.303333333 0.276666667 -0.132755209 Down 0.107704314 Zfp78 zinc finger protein 78 K09228|1|0.0|946|mmu:330463|KRAB domain-containing zinc finger protein - GO:0043169//cation binding;GO:0043169//cation binding;GO:0043169//cation binding - gi|68448539|ref|NP_001020334.1|/0/zinc finger protein 471 isoform 1 [Mus musculus] 17702 2162 0.33 0.36 0.125530882 Up 0.107704314 Msx2 msh homeobox 2 K09341|1|3e-136|488|mmu:17702|homeobox protein MSX GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle "GO:0000988//transcription factor activity, protein binding;GO:0005515//protein binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding" "GO:0030326//embryonic limb morphogenesis;GO:0003272//endocardial cushion formation;GO:0006915//apoptotic process;GO:0048754//branching morphogenesis of an epithelial tube;GO:0043392//negative regulation of DNA binding;GO:0034505//tooth mineralization;GO:0002062//chondrocyte differentiation;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0044319//wound healing, spreading of cells;GO:0030509//BMP signaling pathway;GO:0003151//outflow tract morphogenesis;GO:0045444//fat cell differentiation;GO:0001649//osteoblast differentiation;GO:0060363//cranial suture morphogenesis;GO:0070848//response to growth factor;GO:0030216//keratinocyte differentiation;GO:0060350//endochondral bone morphogenesis;GO:0008283//cell proliferation;GO:0003002//regionalization;GO:0032355//response to estradiol;GO:0030879//mammary gland development;GO:0042637//catagen;GO:0035878//nail development" "gi|148709179|gb|EDL41125.1|/2.97398e-144/homeobox, msh-like 2, partial [Mus musculus]" 70645 1557 0.32 0.35 0.129283017 Up 0.107704314 Oip5 Opa interacting protein 5 K11565|1|2e-136|488|mmu:70645|opa-interacting protein 5 GO:0044427;GO:0016604//nuclear body - GO:0000087//mitotic M phase gi|111120325|ref|NP_001036118.1|/1.65597e-135/protein Mis18-beta [Mus musculus] 100113398 1413 0.356666667 0.39 0.128897733 Up 0.107704314 Adat3 "adenosine deaminase, tRNA-specific 3" K15442|1|6e-179|629|mmu:100113398|tRNA-specific adenosine deaminase 3 - GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0006399//tRNA metabolic process gi|154759286|ref|NP_001094076.1|/5.26352e-178/probable inactive tRNA-specific adenosine deaminase-like protein 3 [Mus musculus] 71924 2929 0.316666667 0.346666667 0.13058411 Up 0.107704314 Tube1 epsilon-tubulin 1 K10391|1|0.0|917|mmu:71924|tubulin epsilon GO:0032991//macromolecular complex;GO:0005813//centrosome GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005198//structural molecule activity GO:0031023//microtubule organizing center organization;GO:0009154//purine ribonucleotide catabolic process;GO:0022402//cell cycle process;GO:0043623//cellular protein complex assembly gi|58037275|ref|NP_082282.1|/0/tubulin epsilon chain [Mus musculus] 19660 672 0.086666667 0.07 -0.308122295 Down 0.107582083 Rbp2 "retinol binding protein 2, cellular" K14622|1|1e-75|284|mmu:19660|retinol binding protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005501//retinoid binding GO:0051234//establishment of localization;GO:0001523//retinoid metabolic process;GO:0009888//tissue development gi|344244364|gb|EGW00468.1|/4.06479e-80/Retinol-binding protein 2 [Cricetulus griseus] 72640 5776 0.103333333 0.126666667 0.293731203 Up 0.107582083 Mex3a mex3 RNA binding family member A K15686|1|0.0|778|mmu:72640|RNA-binding protein MEX3 [EC:2.3.2.27] - - - gi|308193357|ref|NP_001025061.2|/0/RNA-binding protein MEX3A [Mus musculus] 270049 5103 0.073333333 0.09 0.295455884 Up 0.107582083 Galntl6 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6 K00710|1|0.0|1293|cfa:486063|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0006464//cellular protein modification process gi|880909835|ref|XP_005075214.2|/0/PREDICTED: polypeptide N-acetylgalactosaminyltransferase-like 6 [Mesocricetus auratus] 74189 4861 0.09 0.11 0.289506617 Up 0.107582083 Phactr3 phosphatase and actin regulator 3 K17594|1|0.0|921|mmu:74189|phosphatase and actin regulator 3 - - - - 382253 3246 0.12 0.096666667 -0.311944006 Down 0.107582083 Cdkl5 cyclin-dependent kinase-like 5 K08824|1|0.0|1816|mmu:382253|cyclin-dependent kinase-like [EC:2.7.11.22] GO:0043231//intracellular membrane-bounded organelle GO:0004674//protein serine/threonine kinase activity;GO:0032550 GO:0006468//protein phosphorylation gi|124244037|ref|NP_001019795.1|/0/cyclin-dependent kinase-like 5 [Mus musculus] 243753 2172 0.07 0.086666667 0.308122295 Up 0.107582083 2010107G12Rik solute carrier family 23 member 4 "K14611|1|0.0|765|cge:100762656|solute carrier family 23 (nucleobase transporter), member 1/2" - - GO:0044763 gi|625214262|ref|XP_007647699.1|/0/PREDICTED: solute carrier family 23 member 2-like [Cricetulus griseus] 12035 7849 0.106666667 0.13 0.285402219 Up 0.107582083 Bcat1 "branched chain aminotransferase 1, cytosolic" K00826|1|0.0|796|mmu:12035|branched-chain amino acid aminotransferase [EC:2.6.1.42] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0004084//branched-chain-amino-acid transaminase activity;GO:0005515//protein binding;GO:0004084//branched-chain-amino-acid transaminase activity GO:0008652//cellular amino acid biosynthetic process;GO:0009063//cellular amino acid catabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0009063//cellular amino acid catabolic process "gi|66792792|ref|NP_001019639.1|/0/branched-chain-amino-acid aminotransferase, cytosolic isoform 1 [Mus musculus] " 229302 1417 0.106666667 0.13 0.285402219 Up 0.107582083 Tm4sf4 transmembrane 4 superfamily member 4 - GO:0031224//intrinsic component of membrane - GO:0009888//tissue development gi|260099688|ref|NP_663514.2|/7.84503e-89/transmembrane 4 L6 family member 4 [Mus musculus] 69528 2971 0.1 0.123333333 0.30256277 Up 0.107582083 1700030J22Rik RIKEN cDNA 1700030J22 gene - - - - gi|58037165|ref|NP_081379.1|/0/uncharacterized protein C16orf46 homolog [Mus musculus] 328424 1798 0.083333333 0.103333333 0.310340121 Up 0.107582083 Kcnrg potassium channel regulator "K03849|1|5e-14|82.0|cmk:103177229|alpha-1,3-glucosyltransferase [EC:2.4.1.265];K11835|2|2e-08|63.5|sko:100377510|ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.4.19.12];K20131|3|3e-08|62.8|cmy:102940364|Rab5 GDP/GTP exchange factor;K15074|4|4e-08|62.4|cbr:CBG18386|BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein" GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0005515//protein binding GO:0051259//protein oligomerization;GO:0051259//protein oligomerization gi|84993724|ref|NP_001034194.1|/9.98122e-143/potassium channel regulatory protein isoform 1 [Mus musculus] 16506 3815 0.103333333 0.083333333 -0.310340121 Down 0.107582083 Kcnd1 "potassium voltage-gated channel, Shal-related family, member 1" K04891|1|0.0|1126|mmu:16506|potassium voltage-gated channel Shal-related subfamily D member 1 GO:0044297//cell body;GO:0005887//integral component of plasma membrane GO:0043169//cation binding;GO:0005267//potassium channel activity GO:0051259//protein oligomerization;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|6680526|ref|NP_032449.1|/0/potassium voltage-gated channel subfamily D member 1 precursor [Mus musculus] 246791 1603 0.11 0.09 -0.289506617 Down 0.107582083 Obox3 oocyte specific homeobox 3 K09314|1|6e-10|61.2|ola:101161018|homeobox protein DLX1/4/6;K09325|3|9e-10|67.8|mmu:195333|homeobox protein goosecoid-like;K09312|4|1e-09|67.4|shr:100934389|homeobox protein CDX;K09337|5|2e-09|66.2|mcc:717550|cone-rod homeobox protein GO:0043231//intracellular membrane-bounded organelle - - gi|188528635|ref|NP_663753.3|/0/oocyte specific homeobox 3 [Mus musculus] 327987 11787 2.003333333 1.946666667 -0.041396622 Down 0.107450449 Med13 mediator complex subunit 13 K15164|1|0.0|3992|mmu:327987|mediator of RNA polymerase II transcription subunit 13 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter gi|124286862|ref|NP_001074400.1|/0/mediator of RNA polymerase II transcription subunit 13 [Mus musculus] 268567 3904 2.383333333 2.323333333 -0.036784586 Down 0.107450449 Tmem229b transmembrane protein 229B - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|564356483|ref|XP_006240338.1|/7.5472e-99/PREDICTED: transmembrane protein 229B isoform X3 [Rattus norvegicus] 67417 6544 2.206666667 2.27 0.040823581 Up 0.107450449 Ears2 "glutamyl-tRNA synthetase 2, mitochondrial" K01885|1|0.0|1012|mmu:67417|glutamyl-tRNA synthetase [EC:6.1.1.17] - - - - 106794 5045.08 2.283333333 2.343333333 0.037420701 Up 0.107450449 Dhx57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 K13026|1|0.0|2435|mmu:106794|ATP-dependent RNA helicase DHX57 [EC:3.6.4.13] - - - gi|40787832|gb|AAH65169.1|/0/Dhx57 protein [Mus musculus] 329502 4477 2.033333333 1.973333333 -0.043212067 Down 0.107450449 Pla2g4e "phospholipase A2, group IVE" K16342|1|0.0|1738|mmu:329502|cytosolic phospholipase A2 [EC:3.1.1.4] GO:0000323//lytic vacuole GO:0043169//cation binding;GO:0004620//phospholipase activity GO:0006644//phospholipid metabolic process gi|63999319|ref|NP_808513.2|/0/cytosolic phospholipase A2 epsilon [Mus musculus] 72836 3499 2.323333333 2.26 -0.039873383 Down 0.107450449 Pot1b protection of telomeres 1B K11109|1|0.0|1242|mmu:72836|protection of telomeres protein 1 - - - gi|76677917|ref|NP_082646.1|/0/protection of telomeres 1B [Mus musculus] 66824 2135 2.146666667 2.203333333 0.037589583 Up 0.107450449 Pycard PYD and CARD domain containing K12799|1|3e-93|345|mmu:66824|apoptosis-associated speck-like protein containing a CARD GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0044297//cell body GO:0016504//peptidase activator activity;GO:0004175//endopeptidase activity;GO:0042802//identical protein binding;GO:0019904//protein domain specific binding;GO:0019899//enzyme binding GO:0010822//positive regulation of mitochondrion organization;GO:0050691//regulation of defense response to virus by host;GO:0010608//posttranscriptional regulation of gene expression;GO:0070555//response to interleukin-1;GO:0002253//activation of immune response;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0072331//signal transduction by p53 class mediator;GO:0002250//adaptive immune response;GO:0072678//T cell migration;GO:0043410//positive regulation of MAPK cascade;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0042742//defense response to bacterium;GO:0032675//regulation of interleukin-6 production;GO:0012502//induction of programmed cell death;GO:0007254//JNK cascade;GO:0006469//negative regulation of protein kinase activity;GO:0097191//extrinsic apoptotic signaling pathway;GO:0032722//positive regulation of chemokine production;GO:0010950//positive regulation of endopeptidase activity;GO:0006907//pinocytosis;GO:0001773//myeloid dendritic cell activation;GO:0050715//positive regulation of cytokine secretion;GO:0032480//negative regulation of type I interferon production;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0032731//positive regulation of interleukin-1 beta production;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0030041//actin filament polymerization;GO:0002495//antigen processing and presentation of peptide antigen via MHC class II;GO:0034612//response to tumor necrosis factor;GO:0032496//response to lipopolysaccharide;GO:0006909//phagocytosis;GO:0042102//positive regulation of T cell proliferation gi|165377185|ref|NP_075747.3|/2.60013e-92/apoptosis-associated speck-like protein containing a CARD [Mus musculus] 474156 2804 2.46 2.396666667 -0.037629046 Down 0.107450449 Zbtb9 zinc finger and BTB domain containing 9 K10496|1|0.0|797|mmu:474156|zinc finger and BTB domain-containing protein 9 GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|54400753|ref|NP_001005916.1|/0/zinc finger and BTB domain-containing protein 9 [Mus musculus] 269181 7172 2.27 2.206666667 -0.040823581 Down 0.107450449 Mgat4a "mannoside acetylglucosaminyltransferase 4, isoenzyme A" "K00738|1|0.0|1043|mmu:269181|alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B [EC:2.4.1.145]" - - - - 320790 11306 2.063333333 2.12 0.039087356 Up 0.107450449 Chd7 chromodomain helicase DNA binding protein 7 K14437|1|0.0|3897|mmu:320790|chromodomain-helicase-DNA-binding protein 7 [EC:3.6.4.12] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0043010//camera-type eye development;GO:0007507//heart development;GO:0030326//embryonic limb morphogenesis;GO:0030252//growth hormone secretion;GO:0043009//chordate embryonic development;GO:0050954//sensory perception of mechanical stimulus;GO:0021675//nerve development;GO:0042471//ear morphogenesis;GO:0035239//tube morphogenesis;GO:0046545//development of primary female sexual characteristics;GO:0048514//blood vessel morphogenesis;GO:0030098//lymphocyte differentiation;GO:0035264//multicellular organism growth;GO:0003013//circulatory system process;GO:0006325//chromatin organization;GO:0008344//adult locomotory behavior" gi|460838688|ref|NP_001264078.1|/0/chromodomain-helicase-DNA-binding protein 7 [Mus musculus] 18771 4328.32 2.636666667 2.573333333 -0.035076847 Down 0.107450449 Pknox1 Pbx/knotted 1 homeobox K16670|1|3e-53|213|bfo:BRAFLDRAFT_114749|homeobox protein Meis2;K15613|3|5e-53|213|xtr:100488182|homeobox protein Meis1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0046983//protein dimerization activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0046983//protein dimerization activity" GO:0030098//lymphocyte differentiation;GO:0001654//eye development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030099//myeloid cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030098//lymphocyte differentiation;GO:0001654//eye development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030099//myeloid cell differentiation;GO:0006366//transcription from RNA polymerase II promoter gi|34368580|ref|NP_057879.2|/0/homeobox protein PKNOX1 [Mus musculus] 22648 3916 1.883333333 1.94 0.042768286 Up 0.107450449 Zfp11 zinc finger protein 11 K09228|1|0.0|1415|mmu:22648|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - "gi|148687565|gb|EDL19512.1|/0/zinc finger protein 11, partial [Mus musculus]" 74385 3165 2.25 2.186666667 -0.041191687 Down 0.107450449 Ap5m1 "adaptor-related protein complex 5, mu 1 subunit" K19023|1|0.0|951|mmu:74385|AP-5 complex subunit mu-1 GO:0005770//late endosome;GO:0005764//lysosome;GO:0030119//AP-type membrane coat adaptor complex - GO:0044765//single-organism transport;GO:0015031//protein transport gi|225543139|ref|NP_653118.3|/0/AP-5 complex subunit mu-1 [Mus musculus] 668208 2850 0.083333333 0.1 0.263034406 Up 0.107300011 Gm13288 predicted gene 13288 K05414|1|1e-37|160|cge:100763520|interferon alpha GO:0044421 GO:0005102//receptor binding GO:0007166//cell surface receptor signaling pathway;GO:0030098//lymphocyte differentiation;GO:0002252;GO:0007049//cell cycle;GO:0012501//programmed cell death gi|149588682|ref|NP_001092311.1|/4.32956e-101/interferon zeta-like precursor [Mus musculus] 108052 3615 0.1 0.12 0.263034406 Up 0.107300011 Slc14a1 "solute carrier family 14 (urea transporter), member 1" K08716|1|0.0|691|mmu:108052|solute carrier family 14 (urea transporter) GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane GO:0042887;GO:0042887;GO:0042887 GO:0044763;GO:0015840//urea transport;GO:0042044//fluid transport;GO:0044763;GO:0015840//urea transport;GO:0042044//fluid transport;GO:0044763;GO:0015840//urea transport;GO:0042044//fluid transport gi|283945614|ref|NP_001164481.1|/0/urea transporter 1 isoform a [Mus musculus] 238988 6083 0.123333333 0.103333333 -0.255257055 Down 0.107300011 Erc2 ELKS/RAB6-interacting/CAST family member 2 K19878|1|0.0|1623|mmu:238988|ELKS/RAB6-interacting/CAST family member 2 GO:0044327//dendritic spine head;GO:0033267;GO:0043232;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0032991//macromolecular complex GO:0019904//protein domain specific binding - gi|37360977|ref|NP_808482.2|/0/ERC protein 2 [Mus musculus] 380660 2130 0.113333333 0.093333333 -0.280107919 Down 0.107300011 Acss3 acyl-CoA synthetase short-chain family member 3 K01908|1|0.0|989|mmu:380660|propionyl-CoA synthetase [EC:6.2.1.17] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016405//CoA-ligase activity;GO:0032550;GO:0016405//CoA-ligase activity;GO:0032550 - "gi|218563741|ref|NP_941038.2|/0/acyl-CoA synthetase short-chain family member 3, mitochondrial isoform 2 [Mus musculus]" 245038 3498 0.096666667 0.116666667 0.271302022 Up 0.107300011 Dclk3 doublecortin-like kinase 3 K17530|1|0.0|1425|mmu:245038|doublecortin-like kinase 3 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007165//signal transduction gi|238776837|ref|NP_766516.2|/0/serine/threonine-protein kinase DCLK3 [Mus musculus] 26877 5222 0.103333333 0.123333333 0.255257055 Up 0.107300011 B3galt1 "UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1" "K07819|1|0.0|682|ptg:102949445|beta-1,3-galactosyltransferase 1 [EC:2.4.1.-]" GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0035250//UDP-galactosyltransferase activity GO:0006464//cellular protein modification process;GO:0030258//lipid modification;GO:0009311//oligosaccharide metabolic process "gi|585161461|ref|XP_006732944.1|/0/PREDICTED: beta-1,3-galactosyltransferase 1 [Leptonychotes weddellii]" 212377 4482 0.12 0.143333333 0.256339753 Up 0.107300011 Mms22l "MMS22-like, DNA repair protein" - GO:0005657//replication fork;GO:0043231//intracellular membrane-bounded organelle - GO:0006259//DNA metabolic process;GO:0006974//cellular response to DNA damage stimulus gi|253970429|ref|NP_955761.2|/0/protein MMS22-like [Mus musculus] 211323 2103 0.116666667 0.096666667 -0.271302022 Down 0.107300011 Nrg1 neuregulin 1 K05455|1|0.0|1038|mmu:211323|neuregulin 1 GO:0043005//neuron projection;GO:0044459;GO:0016021//integral component of membrane;GO:0044424;GO:0045202//synapse;GO:0044421 "GO:0005102//receptor binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0030295//protein kinase activator activity" "GO:0055007//cardiac muscle cell differentiation;GO:0003157//endocardium development;GO:0008284//positive regulation of cell proliferation;GO:0007268//chemical synaptic transmission;GO:0032989;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008645//hexose transport;GO:0048870//cell motility;GO:0016049//cell growth;GO:0006351//transcription, DNA-templated;GO:0046903//secretion;GO:0009895;GO:0010002//cardioblast differentiation;GO:0007265//Ras protein signal transduction;GO:0044708//single-organism behavior;GO:0010001//glial cell differentiation;GO:0008366//axon ensheathment;GO:0030182//neuron differentiation;GO:0043393//regulation of protein binding;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0043241//protein complex disassembly;GO:0007155//cell adhesion;GO:0010659//cardiac muscle cell apoptotic process;GO:0008015//blood circulation;GO:0045860//positive regulation of protein kinase activity;GO:0009611//response to wounding" "gi|124377986|ref|NP_848706.2|/0/pro-neuregulin-1, membrane-bound isoform [Mus musculus]" 78473 2142 0.093333333 0.113333333 0.280107919 Up 0.107300011 Skap1 src family associated phosphoprotein 1 K17699|1|1e-175|619|mmu:78473|src kinase associated phosphoprotein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0019900//kinase binding;GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0019900//kinase binding;GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0019900//kinase binding;GO:0008289//lipid binding;GO:0019904//protein domain specific binding GO:0050851//antigen receptor-mediated signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006366//transcription from RNA polymerase II promoter gi|295444856|ref|NP_001171369.1|/0/src kinase-associated phosphoprotein 1 isoform 2 [Mus musculus] 100009664 2398 0.08 0.096666667 0.273018494 Up 0.107300011 F630206G17Rik RIKEN cDNA F630206G17 gene - - - - - 71988 2899 0.116666667 0.096666667 -0.271302022 Down 0.107300011 Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 K11268|1|0.0|1105|mmu:71988|N-acetyltransferase [EC:2.3.1.-] - - - - 20511 11527.17 0.14 0.116666667 -0.263034406 Down 0.107300011 Slc1a2 "solute carrier family 1 (glial high affinity glutamate transporter), member 2" "K05613|1|0.0|936|mmu:20511|solute carrier family 1 (glial high affinity glutamate transporter), member 2" - - - - 107815 4881 0.096666667 0.08 -0.273018494 Down 0.107300011 Scml2 sex comb on midleg-like 2 (Drosophila) K11465|1|0.0|1418|mmu:107815|sex comb on midleg-like protein 2 - - - - 238463 3122 0.096666667 0.08 -0.273018494 Down 0.107300011 Tubal3 "tubulin, alpha-like 3" K07374|1|0.0|877|mmu:238463|tubulin alpha GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005198//structural molecule activity GO:0009154//purine ribonucleotide catabolic process;GO:0044763;GO:0043623//cellular protein complex assembly gi|224809300|ref|NP_001029051.2|/0/tubulin alpha chain-like 3 [Mus musculus] 13605 4002 0.12 0.143333333 0.256339753 Up 0.107300011 Ect2 ect2 oncogene "K01634|1|1e-73|281|tsp:Tsp_06755|sphinganine-1-phosphate aldolase [EC:4.1.2.27];K10728|3|2e-31|140|bfo:BRAFLDRAFT_82314|topoisomerase (DNA) II binding protein 1;K05720|5|2e-28|130|hst:105185175|FYVE, RhoGEF and PH domain containing 1" GO:0043296//apical junction complex;GO:0032155;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0043296//apical junction complex;GO:0032155;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0044444//cytoplasmic part;GO:0043296//apical junction complex;GO:0032155;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0044444//cytoplasmic part GO:0008289//lipid binding;GO:0060089;GO:0008047//enzyme activator activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0042802//identical protein binding;GO:0017016//Ras GTPase binding;GO:0008289//lipid binding;GO:0060089;GO:0008047//enzyme activator activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0042802//identical protein binding;GO:0017016//Ras GTPase binding;GO:0008289//lipid binding;GO:0060089;GO:0008047//enzyme activator activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0042802//identical protein binding;GO:0017016//Ras GTPase binding GO:0034614//cellular response to reactive oxygen species;GO:0006915//apoptotic process;GO:0032989;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0051592//response to calcium ion;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0010212//response to ionizing radiation;GO:0030182//neuron differentiation;GO:0006606//protein import into nucleus;GO:0007043//cell-cell junction assembly;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0051259//protein oligomerization;GO:0045860//positive regulation of protein kinase activity;GO:0032467//positive regulation of cytokinesis;GO:0034614//cellular response to reactive oxygen species;GO:0006915//apoptotic process;GO:0032989;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0051592//response to calcium ion;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0010212//response to ionizing radiation;GO:0030182//neuron differentiation;GO:0006606//protein import into nucleus;GO:0007043//cell-cell junction assembly;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0051259//protein oligomerization;GO:0045860//positive regulation of protein kinase activity;GO:0032467//positive regulation of cytokinesis;GO:0034614//cellular response to reactive oxygen species;GO:0006915//apoptotic process;GO:0032989;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0051592//response to calcium ion;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0010212//response to ionizing radiation;GO:0030182//neuron differentiation;GO:0006606//protein import into nucleus;GO:0007043//cell-cell junction assembly;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0051259//protein oligomerization;GO:0045860//positive regulation of protein kinase activity;GO:0032467//positive regulation of cytokinesis gi|60360116|dbj|BAD90277.1|/0/mKIAA4037 protein [Mus musculus] 52614 3491 0.08 0.096666667 0.273018494 Up 0.107300011 Adgre4 adhesion G protein-coupled receptor E4 "K08445|1|0.0|1349|mmu:52614|egf-like module containing, mucin-like, hormone receptor-like 4" GO:0031224//intrinsic component of membrane;GO:0044464 GO:0046872//metal ion binding;GO:0004888//transmembrane signaling receptor activity GO:0007186//G-protein coupled receptor signaling pathway gi|225690579|ref|NP_631877.2|/0/adhesion G protein-coupled receptor E4 precursor [Mus musculus] 228421 3487 0.096666667 0.116666667 0.271302022 Up 0.107300011 Kif18a kinesin family member 18A K10401|1|0.0|1706|mmu:228421|kinesin family member 18/19 - - - - 22598 4037 0.113333333 0.093333333 -0.280107919 Down 0.107300011 Slc6a18 "solute carrier family 6 (neurotransmitter transporter), member 18" "K05048|1|0.0|1238|mmu:22598|solute carrier family 6 (neurotransmitter transporter, amino acid/orphan) member 15/16/17/18/20" GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity GO:0006970//response to osmotic stress;GO:0046942//carboxylic acid transport;GO:0006970//response to osmotic stress;GO:0046942//carboxylic acid transport;GO:0006970//response to osmotic stress;GO:0046942//carboxylic acid transport;GO:0006970//response to osmotic stress;GO:0046942//carboxylic acid transport;GO:0006970//response to osmotic stress;GO:0046942//carboxylic acid transport gi|209862996|ref|NP_001129559.1|/0/sodium-dependent neutral amino acid transporter B(0)AT3 isoform 2 [Mus musculus] 11671 3193 11.73 11.6 -0.016078208 Down 0.107224792 Aldh3a2 "aldehyde dehydrogenase family 3, subfamily A2" K00128|1|0.0|903|mmu:11671|aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane;GO:0042579//microbody;GO:0005789//endoplasmic reticulum membrane "GO:0004029//aldehyde dehydrogenase (NAD) activity;GO:0016899//oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor" GO:0009888//tissue development;GO:0007399//nervous system development;GO:0034308;GO:0006721//terpenoid metabolic process;GO:0006081//cellular aldehyde metabolic process gi|564372361|ref|XP_006246591.1|/0/PREDICTED: fatty aldehyde dehydrogenase isoform X1 [Rattus norvegicus] 52846 3205 9.48 9.35 -0.019920694 Down 0.107224792 Cnot11 "CCR4-NOT transcription complex, subunit 11" K08740|1|3e-45|186|smm:Smp_172620|DNA mismatch repair protein MSH4 GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0005488//binding "GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0044699" gi|26553441|ref|NP_082319.1|/0/CCR4-NOT transcription complex subunit 11 [Mus musculus] 18475 4241 7.78 7.913333333 0.024515374 Up 0.107224792 Pafah1b2 "platelet-activating factor acetylhydrolase, isoform 1b, subunit 2" K16795|1|2e-130|469|rno:64189|platelet-activating factor acetylhydrolase IB subunit beta/gamma [EC:3.1.1.47] - - - - 80280 2269 10.39666667 10.52333333 0.017470708 Up 0.107224792 Cdk5rap3 CDK5 regulatory subunit associated protein 3 K20349|1|3e-95|352|nvi:100117556|p24 family protein gamma-3 - - - - 76952 3778.43 10.80666667 10.67333333 -0.017910783 Down 0.107224792 Nt5c2 "5'-nucleotidase, cytosolic II" K01081|1|0.0|1147|rno:100363253|5'-nucleotidase [EC:3.1.3.5] GO:0044424;GO:0044424;GO:0044444//cytoplasmic part;GO:0044424 "GO:0008252//nucleotidase activity;GO:0043169//cation binding;GO:0008252//nucleotidase activity;GO:0043169//cation binding;GO:0043169//cation binding;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0008252//nucleotidase activity;GO:0036094//small molecule binding;GO:0008252//nucleotidase activity;GO:0043169//cation binding" GO:0046128;GO:0009150//purine ribonucleotide metabolic process;GO:0046128;GO:0009150//purine ribonucleotide metabolic process;GO:0046128;GO:0009112;GO:0009150//purine ribonucleotide metabolic process;GO:0046128;GO:0009150//purine ribonucleotide metabolic process gi|256665234|ref|NP_001157835.1|/0/cytosolic purine 5'-nucleotidase isoform 1 [Mus musculus] 54723 3549 11.52 11.65333333 0.016601967 Up 0.107224792 Tfip11 tuftelin interacting protein 11 K13103|1|0.0|1588|mmu:54723|tuftelin-interacting protein 11 GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0031012//extracellular matrix GO:0003676//nucleic acid binding "GO:0043062//extracellular structure organization;GO:0048869//cellular developmental process;GO:0009888//tissue development;GO:0006396//RNA processing;GO:0006351//transcription, DNA-templated" gi|10190660|ref|NP_061253.2|/0/tuftelin-interacting protein 11 [Mus musculus] 68440 1417 9.136666667 9.006666667 -0.020674654 Down 0.107224792 Dusp23 dual specificity phosphatase 23 K14165|1|8e-73|276|mmu:68440|atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen GO:0004721//phosphoprotein phosphatase activity GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|55926215|ref|NP_081001.1|/6.65163e-72/dual specificity protein phosphatase 23 [Mus musculus] 70900 3142 9.446666667 9.58 0.020220304 Up 0.107224792 4921517D22Rik RIKEN cDNA 4921517D22 gene K11253|1|1e-31|123|ggo:101140048|histone H3 - - - "gi|148709339|gb|EDL41285.1|/1.52934e-163/RIKEN cDNA 4921517D22, partial [Mus musculus]" 224432 4193 7.693333333 7.82 0.023559789 Up 0.107224792 Scaf4 SR-related CTD-associated factor 4 "K13167|1|7e-145|518|mmu:224432|splicing factor, arginine/serine-rich 15" - - - "gi|148665971|gb|EDK98387.1|/6.82862e-146/mCG129573, isoform CRA_b, partial [Mus musculus]" 23827 2182 8.493333333 8.62 0.021356998 Up 0.107224792 Bpnt1 bisphosphate 3'-nucleotidase 1 "K01082|1|3e-175|617|mmu:23827|3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]" - GO:0016312//inositol bisphosphate phosphatase activity;GO:0008252//nucleotidase activity;GO:0043169//cation binding GO:0046488//phosphatidylinositol metabolic process "gi|39652626|ref|NP_035924.2|/2.79173e-174/3'(2'),5'-bisphosphate nucleotidase 1 [Mus musculus]" 72195 2692 8.34 8.47 0.022314586 Up 0.107224792 Supt7l suppressor of Ty 7-like K11316|1|0.0|717|mmu:72195|STAGA complex 65 subunit gamma GO:0070461//SAGA-type complex GO:0003712//transcription cofactor activity;GO:0008080//N-acetyltransferase activity "GO:0034504//protein localization to nucleus;GO:0006351//transcription, DNA-templated;GO:0016573//histone acetylation" gi|58037285|ref|NP_082426.1|/0/STAGA complex 65 subunit gamma [Mus musculus] 50497 1874.83 10.47333333 10.6 0.017343585 Up 0.107224792 Hspa14 heat shock protein 14 K09230|1|9e-19|99.4|ptg:102968956|SCAN domain-containing zinc finger protein GO:0044444//cytoplasmic part;GO:0030529//intracellular ribonucleoprotein complex;GO:0044444//cytoplasmic part GO:0032550;GO:0032550 GO:0006458//'de novo' protein folding;GO:0050896//response to stimulus gi|755496830|ref|XP_011237283.1|/0/PREDICTED: heat shock 70 kDa protein 14 isoform X2 [Mus musculus] 11778 5823 8.876666667 9.003333333 0.020441211 Up 0.107224792 Ap3s2 "adaptor-related protein complex 3, sigma 2 subunit" K12399|1|6e-105|385|fca:101082825|AP-3 complex subunit sigma GO:0043231//intracellular membrane-bounded organelle;GO:0030119//AP-type membrane coat adaptor complex;GO:0012506//vesicle membrane GO:0022892//substrate-specific transporter activity GO:0008088//axo-dendritic transport;GO:0048489//synaptic vesicle transport;GO:0015031//protein transport gi|26350839|dbj|BAC39056.1|/3.57805e-140/unnamed protein product [Mus musculus] 230648 4320 8.206666667 8.336666667 0.022674296 Up 0.107224792 Efcab14 EF-hand calcium binding domain 14 K14570|1|1e-11|75.9|isc:IscW_ISCW008155|RNA exonuclease 1 [EC:3.1.-.-];K20358|2|3e-07|60.8|cfa:480708|golgin subfamily A member 2;K20478|3|1e-06|59.3|gfr:102032680|golgin subfamily B member 1;K16808|4|1e-06|58.9|xma:102230200|nuclear mitotic apparatus protein 1;K20282|5|2e-06|58.5|phi:102110179|GRIP and coiled-coil domain-containing protein 2 - GO:0046872//metal ion binding - gi|40254242|ref|NP_766286.2|/0/EF-hand calcium-binding domain-containing protein 14 [Mus musculus] 73062 2675 11.17666667 11.04333333 -0.01731428 Down 0.107224792 Ppp1r16a "protein phosphatase 1, regulatory (inhibitor) subunit 16A" K17458|1|0.0|1007|mmu:73062|protein phosphatase 1 regulatory subunit 16A GO:0044444//cytoplasmic part;GO:0016020//membrane - - gi|39930481|ref|NP_203535.1|/0/protein phosphatase 1 regulatory subunit 16A [Mus musculus] 494448 5449 9.003333333 8.876666667 -0.020441211 Down 0.107224792 Cbx6 chromobox 6 K11453|1|1e-172|610|mmu:494448|chromobox protein 6 - - - - 22289 5935 1.41 1.363333333 -0.04855682 Down 0.107102561 Kdm6a lysine (K)-specific demethylase 6A K11447|1|0.0|2651|mmu:22289|histone demethylase [EC:1.14.11.-] GO:0043231//intracellular membrane-bounded organelle;GO:0034708;GO:0043231//intracellular membrane-bounded organelle;GO:0034708 "GO:0043169//cation binding;GO:0032452//histone demethylase activity;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0032452//histone demethylase activity;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0043169//cation binding" GO:0014020;GO:0016055//Wnt signaling pathway;GO:0044710;GO:0003008;GO:0006325//chromatin organization;GO:0030903//notochord development;GO:0000578//embryonic axis specification;GO:0001707//mesoderm formation;GO:0014020;GO:0016055//Wnt signaling pathway;GO:0030903//notochord development;GO:0044710;GO:0000578//embryonic axis specification;GO:0001707//mesoderm formation;GO:0034968//histone lysine methylation;GO:0003008 gi|882938999|ref|NP_001297373.1|/0/lysine-specific demethylase 6A isoform 2 [Mus musculus] 243725 9547 1.24 1.286666667 0.053298226 Up 0.107102561 Ppp1r9a "protein phosphatase 1, regulatory (inhibitor) subunit 9A" K17551|1|0.0|1999|mmu:243725|neurabin GO:0030425//dendrite;GO:0015629//actin cytoskeleton GO:0008092//cytoskeletal protein binding GO:0048869//cellular developmental process;GO:0048731//system development;GO:0030030//cell projection organization;GO:0019932//second-messenger-mediated signaling;GO:0030036//actin cytoskeleton organization gi|31711997|ref|NP_853626.1|/0/neurabin-1 [Mus musculus] 19085 2632.18 1.493333333 1.543333333 0.047513461 Up 0.107102561 Prkar1b "protein kinase, cAMP dependent regulatory, type I beta" K04739|1|0.0|765|mmu:19085|cAMP-dependent protein kinase regulator GO:0016020//membrane;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0030551//cyclic nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0030551//cyclic nucleotide binding;GO:0019887//protein kinase regulator activity" GO:0009653//anatomical structure morphogenesis;GO:0015980//energy derivation by oxidation of organic compounds;GO:0007599//hemostasis;GO:0038127//ERBB signaling pathway;GO:0033762//response to glucagon;GO:0032147//activation of protein kinase activity;GO:0010863//positive regulation of phospholipase C activity;GO:0030073//insulin secretion;GO:0044708//single-organism behavior;GO:0042044//fluid transport;GO:0009653//anatomical structure morphogenesis;GO:0015980//energy derivation by oxidation of organic compounds;GO:0007599//hemostasis;GO:0038127//ERBB signaling pathway;GO:0033762//response to glucagon;GO:0032147//activation of protein kinase activity;GO:0010863//positive regulation of phospholipase C activity;GO:0030073//insulin secretion;GO:0044708//single-organism behavior;GO:0042044//fluid transport gi|254675178|ref|NP_032949.3|/0/cAMP-dependent protein kinase type I-beta regulatory subunit [Mus musculus] 269955 2340 1.44 1.39 -0.050983929 Down 0.107102561 Rccd1 RCC1 domain containing 1 K19607|1|2e-20|103|hmg:100213911|X-linked retinitis pigmentosa GTPase regulator;K10615|2|3e-20|103|smm:Smp_142890|E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26];K10614|3|5e-20|102|cmk:103184503|E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26] - - - gi|289666776|ref|NP_775621.2|/0/RCC1 domain-containing protein 1 [Mus musculus] 77805 4540 1.44 1.386666667 -0.054447784 Down 0.107102561 Esco1 establishment of sister chromatid cohesion N-acetyltransferase 1 K11268|1|0.0|1541|mmu:77805|N-acetyltransferase [EC:2.3.1.-] - - - - 72350 4482 1.383333333 1.433333333 0.051225323 Up 0.107102561 Zc2hc1c "zinc finger, C2HC-type containing 1C" K00234|1|2e-11|74.7|cfo:105251968|succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1] - GO:0043169//cation binding - gi|268370213|ref|NP_766002.2|/0/zinc finger C2HC domain-containing protein 1C [Mus musculus] 22764 6944 1.426666667 1.473333333 0.046435573 Up 0.107102561 Zfx zinc finger protein X-linked K09228|1|2e-70|271|bfo:BRAFLDRAFT_114614|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0050896//response to stimulus;GO:0040007//growth;GO:0042592//homeostatic process;GO:0048232//male gamete generation;GO:0007281//germ cell development;GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organism development;GO:0050896//response to stimulus;GO:0040007//growth;GO:0042592//homeostatic process;GO:0048232//male gamete generation;GO:0007281//germ cell development;GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organism development" gi|569010000|ref|XP_006528028.1|/0/PREDICTED: zinc finger X-chromosomal protein isoform X2 [Mus musculus] 83433 1091 1.57 1.62 0.045229254 Up 0.107102561 Trem2 triggering receptor expressed on myeloid cells 2 K14378|1|7e-103|376|mmu:83433|triggering receptor expressed on myeloid cells 2 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0038023//signaling receptor activity;GO:0038023//signaling receptor activity GO:0007154//cell communication;GO:0007154//cell communication gi|440918700|ref|NP_001259007.1|/1.21359e-112/triggering receptor expressed on myeloid cells 2 isoform 2 precursor [Mus musculus] 353326 5235 1.726666667 1.673333333 -0.045264734 Down 0.107102561 Rtl1 retrotransposon-like 1 K10798|1|2e-44|184|dre:558045|poly [ADP-ribose] polymerase [EC:2.4.2.30];K04612|2|9e-18|96.3|mze:101472134|calcium-sensing receptor;K02184|3|2e-17|95.5|ocu:100356313|formin 2 GO:0031224//intrinsic component of membrane - GO:0032502//developmental process gi|46309585|ref|NP_908998.1|/0/retrotransposon-like protein 1 [Mus musculus] 20585 4723.7 1.43 1.483333333 0.052827688 Up 0.107102561 Hltf helicase-like transcription factor K15711|1|0.0|1961|mmu:20585|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:3.6.4.- 2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0003676//nucleic acid binding GO:0006366//transcription from RNA polymerase II promoter;GO:0009154//purine ribonucleotide catabolic process;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0009154//purine ribonucleotide catabolic process;GO:0006325//chromatin organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0009154//purine ribonucleotide catabolic process;GO:0006325//chromatin organization gi|67763824|ref|NP_033236.2|/0/helicase-like transcription factor [Mus musculus] 320879 1954 0.403333333 0.37 -0.124447371 Down 0.106792283 B230217O12Rik RIKEN cDNA B230217O12 gene - - - - - 72898 1604 0.336666667 0.31 -0.119052672 Down 0.106792283 Asphd2 aspartate beta-hydroxylase domain containing 2 K00476|1|3e-25|119|sko:100369952|aspartate beta-hydroxylase [EC:1.14.11.16] GO:0031227//intrinsic component of endoplasmic reticulum membrane "GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0006464//cellular protein modification process;GO:0044710 gi|55926229|ref|NP_082662.1|/0/aspartate beta-hydroxylase domain-containing protein 2 [Mus musculus] 320106 1606 0.343333333 0.316666667 -0.116644919 Down 0.106792283 Slc38a11 "solute carrier family 38, member 11" "K14997|1|0.0|870|mmu:320106|solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 11" - - - gi|114205381|ref|NP_796048.2|/0/putative sodium-coupled neutral amino acid transporter 11 [Mus musculus] 70472 5683 0.363333333 0.333333333 -0.124328135 Down 0.106792283 Atad2 "ATPase family, AAA domain containing 2" K13525|1|2e-54|218|hro:HELRODRAFT_65100|transitional endoplasmic reticulum ATPase GO:0031981//nuclear lumen GO:0017111//nucleoside-triphosphatase activity;GO:0032550 "GO:0006351//transcription, DNA-templated" gi|91199557|ref|NP_081711.2|/0/ATPase family AAA domain-containing protein 2 [Mus musculus] 329371 4020 0.39 0.423333333 0.118319967 Up 0.106792283 Dbhos "dopamine beta hydroxylase, opposite strand" - - GO:0017111//nucleoside-triphosphatase activity;GO:0032550 - "gi|148676412|gb|EDL08359.1|/5.79614e-86/mCG145106, partial [Mus musculus]" 211001 2850 0.726666667 0.69 -0.074697367 Down 0.106604235 8030423F21Rik RIKEN cDNA 8030423F21 gene - - - - - 67138 5279 0.76 0.8 0.074000581 Up 0.106604235 Herc6 hect domain and RLD 6 K10615|1|2e-178|630|cmk:103184502|E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26];K10614|4|8e-178|627|acs:100563151|E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26] - - - gi|60097906|ref|NP_080268.1|/0/E3 ISG15--protein ligase Herc6 [Mus musculus] 93695 3798 0.783333333 0.746666667 -0.069162025 Down 0.106604235 Gpnmb glycoprotein (transmembrane) nmb K17304|1|1e-43|181|lcm:102365525|melanocyte protein PMEL GO:0048770;GO:0016021//integral component of membrane GO:0005539//glycosaminoglycan binding;GO:0005102//receptor binding GO:0001503//ossification;GO:0022610 gi|74192694|dbj|BAE34867.1|/0/unnamed protein product [Mus musculus] 242702 5578 0.833333333 0.873333333 0.067638717 Up 0.106604235 Myom3 "myomesin family, member 3" K12567|1|2e-72|278|dre:100001684|titin [EC:2.7.11.1] - - - - 22063 4472 0.923333333 0.88 -0.069348047 Down 0.106604235 Trpc1 "transient receptor potential cation channel, subfamily C, member 1" K04964|1|0.0|1482|mmu:22063|transient receptor potential cation channel subfamily C member 1 - - - gi|940725786|ref|XP_014308703.1|/0/PREDICTED: short transient receptor potential channel 1 [Myotis lucifugus] 320817 8102 0.733333333 0.696666667 -0.074000581 Down 0.106604235 Atad2b "ATPase family, AAA domain containing 2B" K14575|1|6e-56|223|pbi:103053380|AAA family ATPase;K13525|5|2e-55|221|xtr:448177|transitional endoplasmic reticulum ATPase - GO:0042393//histone binding;GO:0032550;GO:0016462//pyrophosphatase activity - gi|153791220|ref|NP_001093098.1|/0/ATPase family AAA domain-containing protein 2B [Mus musculus] 56868 2179 0.77 0.81 0.073063462 Up 0.106604235 Psg23 pregnancy-specific glycoprotein 23 K06499|1|6e-121|437|mmu:384557|carcinoembryonic antigen-related cell adhesion molecule - GO:0005515//protein binding GO:0001525//angiogenesis;GO:0044703;GO:0038044;GO:0002376//immune system process;GO:0010467//gene expression;GO:0009690//cytokinin metabolic process;GO:0032653 gi|19549329|ref|NP_064657.2|/0/pregnancy-specific glycoprotein 23 [Mus musculus] 330914 9969 0.726666667 0.763333333 0.071019463 Up 0.106604235 Arhgap32 Rho GTPase activating protein 32 K17933|1|2e-130|471|gja:107108176|Rho GTPase-activating protein 33 GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0097060//synaptic membrane GO:0005543//phospholipid binding GO:0007265//Ras protein signal transduction gi|307344692|ref|NP_001182561.1|/0/rho GTPase-activating protein 32 isoform 1 [Mus musculus] 67475 4255 0.863333333 0.903333333 0.065340754 Up 0.106604235 Ero1lb ERO1-like beta (S. cerevisiae) K10976|1|0.0|881|mmu:67475|ERO1-like protein beta [EC:1.8.4.-] - - - - 384763 3671 0.85 0.89 0.066342495 Up 0.106604235 Zfp667 zinc finger protein 667 K09228|1|0.0|1222|mmu:384763|KRAB domain-containing zinc finger protein GO:0005622//intracellular GO:0046872//metal ion binding "GO:0006351//transcription, DNA-templated" gi|67972433|ref|NP_001020099.1|/0/zinc finger protein 667 [Mus musculus] 67936 1499 8.783333333 8.66 -0.020401531 Down 0.106312761 Wdr55 WD repeat domain 55 K16482|1|2e-15|86.3|lcm:102352521|centriolar protein POC1 GO:0031981//nuclear lumen - GO:0042254//ribosome biogenesis gi|27229061|ref|NP_080740.2|/0/WD repeat-containing protein 55 [Mus musculus] 110593 7569.87 11.22666667 11.11 -0.015070821 Down 0.106312761 Prdm2 "PR domain containing 2, with ZNF domain" K11432|1|0.0|2539|mmu:110593|PR domain zinc finger protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0043627//response to estrogen;GO:0006351//transcription, DNA-templated;GO:0043627//response to estrogen;GO:0006351//transcription, DNA-templated" gi|373838731|ref|NP_001243309.1|/0/PR domain zinc finger protein 2 isoform b [Mus musculus] 13872 2673 8.88 8.76 -0.019628807 Down 0.106312761 Ercc3 "excision repair cross-complementing rodent repair deficiency, complementation group 3" K10843|1|0.0|1475|mmu:13872|DNA excision repair protein ERCC-3 [EC:3.6.4.12] GO:0005667//transcription factor complex "GO:0032550;GO:0005515//protein binding;GO:0033218//amide binding;GO:0032558//adenyl deoxyribonucleotide binding;GO:0003676//nucleic acid binding;GO:0004674//protein serine/threonine kinase activity;GO:0042623//ATPase activity, coupled;GO:0003678//DNA helicase activity" GO:0033036;GO:0006366//transcription from RNA polymerase II promoter;GO:0009913//epidermal cell differentiation;GO:0009411//response to UV;GO:0006289//nucleotide-excision repair;GO:0022402//cell cycle process;GO:0012502//induction of programmed cell death;GO:0006464//cellular protein modification process;GO:0009154//purine ribonucleotide catabolic process;GO:0071103//DNA conformation change gi|19526800|ref|NP_598419.1|/0/TFIIH basal transcription factor complex helicase XPB subunit [Mus musculus] 228869 3151 9.026666667 8.903333333 -0.019847763 Down 0.106312761 Ncoa5 nuclear receptor coactivator 5 K19756|1|4e-20|103|hro:HELRODRAFT_193795|radial spoke head protein 4A - - - gi|148674494|gb|EDL06441.1|/0/nuclear receptor coactivator 5 [Mus musculus] 66204 677 7.566666667 7.45 -0.022417466 Down 0.106312761 Acyp1 "acylphosphatase 1, erythrocyte (common) type" K01512|1|3e-51|203|mmu:66204|acylphosphatase [EC:3.6.1.7] - "GO:0016818//hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides" - "gi|148670916|gb|EDL02863.1|/1.3651e-75/acylphosphatase 1, erythrocyte (common) type, isoform CRA_c, partial [Mus musculus]" 98710 2005 6.73 6.846666667 0.024795271 Up 0.106312761 Rabif RAB interacting factor K19952|1|5e-68|261|mmu:98710|guanine nucleotide exchange factor - GO:0046914//transition metal ion binding;GO:0030695//GTPase regulator activity GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization gi|21704004|ref|NP_663485.1|/4.5807e-67/guanine nucleotide exchange factor MSS4 [Mus musculus] 445007 2181 7.866666667 7.99 0.022443049 Up 0.106312761 Nup85 nucleoporin 85 K14304|1|0.0|1279|mmu:445007|nuclear pore complex protein Nup85 "GO:0005643//nuclear pore;GO:0000775//chromosome, centromeric region;GO:0005819//spindle" - GO:0050658//RNA transport;GO:0045184//establishment of protein localization;GO:0030595//leukocyte chemotaxis;GO:0030031//cell projection assembly gi|12856972|dbj|BAB30848.1|/0/unnamed protein product [Mus musculus] 66082 2018 8.756666667 8.88 0.020177882 Up 0.106312761 Abhd6 abhydrolase domain containing 6 K13700|1|0.0|685|mmu:66082|abhydrolase domain-containing protein 6 [EC:3.1.1.23] - - - - 625360 1678 0.093333333 0.11 0.237039197 Up 0.106124713 BC147527 cDNA sequence BC147527 - - - - "gi|85702324|ref|NP_001033014.1|/1.09068e-95/2-cell-stage, variable group, member 3-like [Mus musculus]" 27389 1071 0.11 0.13 0.2410081 Up 0.106124713 Dusp13 dual specificity phosphatase 13 K14165|1|8e-138|492|rno:100909469|atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] - - - gi|821024030|ref|XP_012358348.1|/0/PREDICTED: dual specificity protein phosphatase 13 isoform X1 [Nomascus leucogenys] 242914 2249 0.13 0.11 -0.2410081 Down 0.106124713 Gm4961 kinesin superfamily protein 2C pseudogene K10393|1|2e-178|440|mmu:73804|kinesin family member 2/24 - - - - 328833 4509 0.146666667 0.123333333 -0.249978253 Down 0.106124713 Treml2 triggering receptor expressed on myeloid cells-like 2 K14364|1|2e-172|610|mmu:328833|trem-like transcript 2 protein GO:0044464;GO:0031224//intrinsic component of membrane - GO:0046649//lymphocyte activation gi|133908636|ref|NP_001028577.2|/1.33659e-171/trem-like transcript 2 protein precursor [Mus musculus] 193452 2730 0.146666667 0.123333333 -0.249978253 Down 0.106124713 Zfp184 zinc finger protein 184 (Kruppel-like) K09228|1|0.0|1577|mmu:193452|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|33942078|ref|NP_898835.1|/0/zinc finger protein 184 [Mus musculus] 12517 1482.65 3.693333333 3.766666667 0.028364891 Up 0.106011885 Cd72 CD72 antigen K06504|1|0.0|638|mmu:12517|CD72 antigen GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0031224//intrinsic component of membrane;GO:0016021//integral component of membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - gi|160333097|ref|NP_031680.2|/0/B-cell differentiation antigen CD72 isoform 2 [Mus musculus] 68642 1028 3.266666667 3.336666667 0.03058832 Up 0.106011885 Tmem216 transmembrane protein 216 K19385|1|5e-63|243|mmu:68642|transmembrane protein 216 - - - gi|821125788|ref|XP_012384803.1|/3.06856e-67/PREDICTED: transmembrane protein 216 isoform X2 [Dasypus novemcinctus] 269529 4655 3.303333333 3.233333333 -0.03090031 Down 0.106011885 Fbxo10 F-box protein 10 K10296|1|0.0|1867|mmu:269529|F-box protein 10 - - - "gi|32451765|gb|AAH54731.1|/0/Fbxo10 protein, partial [Mus musculus]" 17248 7107 3.59 3.663333333 0.029173136 Up 0.106011885 Mdm4 transformed mouse 3T3 cell double minute 4 K10127|1|0.0|942|mmu:17248|protein Mdm4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0009895;GO:0007050//cell cycle arrest;GO:0001666//response to hypoxia;GO:0065003;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0009895;GO:0007050//cell cycle arrest;GO:0001666//response to hypoxia;GO:0065003;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0009895;GO:0007050//cell cycle arrest;GO:0001666//response to hypoxia;GO:0065003;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0009895;GO:0007050//cell cycle arrest;GO:0001666//response to hypoxia;GO:0065003;GO:0006366//transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0009895;GO:0007050//cell cycle arrest;GO:0001666//response to hypoxia;GO:0065003 gi|723428419|ref|NP_001289730.1|/0/protein Mdm4 isoform 1 [Mus musculus] 18536 8398 2.883333333 2.95 0.032977322 Up 0.106011885 Pcm1 pericentriolar material 1 K16537|1|0.0|3539|mmu:18536|pericentriolar material 1 protein GO:0005813//centrosome;GO:0072372//primary cilium;GO:0005635//nuclear envelope GO:0005488//binding GO:0044380//protein localization to cytoskeleton;GO:0021846//cell proliferation in forebrain;GO:0031023//microtubule organizing center organization;GO:0010927;GO:0072393//microtubule anchoring at microtubule organizing center;GO:0019827//stem cell population maintenance;GO:0010721//negative regulation of cell development gi|170763496|ref|NP_076151.2|/0/pericentriolar material 1 protein [Mus musculus] 213391 6370 3.736666667 3.666666667 -0.027282754 Down 0.106011885 Rassf4 Ras association (RalGDS/AF-6) domain family member 4 K09851|1|1e-148|531|mmu:213391|Ras association domain-containing protein 2/4 - - GO:0007154//cell communication gi|38174483|gb|AAH60709.1|/8.76436e-148/Ras association (RalGDS/AF-6) domain family member 4 [Mus musculus] 14682 5634 3.81 3.883333333 0.027504551 Up 0.106011885 Gnaq "guanine nucleotide binding protein, alpha q polypeptide" K04634|1|0.0|675|hgl:101715420|guanine nucleotide-binding protein G(q) subunit alpha - - - gi|193502|gb|AAA63306.1|/0/G alpha q subunit [Mus musculus] 12593 3480.08 2.893333333 2.826666667 -0.033630778 Down 0.106011885 Cdyl "chromodomain protein, Y chromosome-like" K00653|1|0.0|1150|mmu:12593|chromodomain protein Y [EC:2.3.1.48] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0042393//histone binding;GO:0008080//N-acetyltransferase activity;GO:0042393//histone binding;GO:0008080//N-acetyltransferase activity "GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated" gi|6753398|ref|NP_034011.1|/0/chromodomain Y-like protein isoform 1 [Mus musculus] 320595 6359 2.97 3.036666667 0.032025622 Up 0.106011885 Phf8 PHD finger protein 8 K19415|1|0.0|1414|cge:100756628|lysine-specific demethylase PHF8 [EC:1.14.11.27] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0032452//histone demethylase activity;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0032452//histone demethylase activity;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0070076//histone lysine demethylation;GO:0000183//chromatin silencing at rDNA;GO:0006360//transcription from RNA polymerase I promoter;GO:0070076//histone lysine demethylation;GO:0000183//chromatin silencing at rDNA;GO:0007417//central nervous system development;GO:0044772//mitotic cell cycle phase transition;GO:0006360//transcription from RNA polymerase I promoter gi|164518891|ref|NP_001106825.1|/0/histone lysine demethylase PHF8 isoform b [Mus musculus] 237898 6978 3.233333333 3.3 0.029443778 Up 0.106011885 Usp32 ubiquitin specific peptidase 32 K11837|1|0.0|3218|mmu:237898|ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle "GO:0046872//metal ion binding;GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process gi|126032299|ref|NP_001025105.1|/0/ubiquitin carboxyl-terminal hydrolase 32 [Mus musculus] 58238 1853 3.373333333 3.306666667 -0.028797264 Down 0.106011885 Fam181b "family with sequence similarity 181, member B" - - - - gi|120587013|ref|NP_067402.2|/0/protein FAM181B [Mus musculus] 269774 19321.39 3.3 3.226666667 -0.032421478 Down 0.106011885 Aak1 AP2 associated kinase 1 K08853|1|0.0|802|mmu:269774|AP2-associated kinase [EC:2.7.11.1] - - - gi|40789031|dbj|BAA83000.2|/0/KIAA1048 protein [Homo sapiens] 242481 8213 0.33 0.356666667 0.112110366 Up 0.105936666 Palm2 paralemmin 2 K16519|1|0.0|702|mmu:242481|A-kinase anchor protein 2 - - - gi|27777697|ref|NP_766456.1|/0/paralemmin-2 [Mus musculus] 78748 3497 0.403333333 0.436666667 0.114559764 Up 0.105936666 Rassf10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 K09856|1|0.0|834|mmu:78748|Ras association domain-containing protein 9/10 GO:0005737//cytoplasm;GO:0044430;GO:0015630//microtubule cytoskeleton - GO:0007154//cell communication gi|26338081|dbj|BAC32726.1|/0/unnamed protein product [Mus musculus] 624866 2361.66 0.443333333 0.41 -0.11276793 Down 0.105936666 Lekr1 "leucine, glutamate and lysine rich 1" - - - - "gi|262263415|ref|NP_001160131.1|/0/leucine-, glutamate- and lysine-rich protein 1 isoform 1 [Mus musculus] " 100532730 872 0.406666667 0.376666667 -0.110558375 Down 0.105936666 C230037L18Rik RIKEN cDNA C230037L18 gene - - - - - 74092 1349 0.373333333 0.403333333 0.111508315 Up 0.105936666 Tbc1d22bos "TBC1 domain family, member 22B, opposite strand" K20360|1|2e-17|92.8|myd:102757952|TBC1 domain family member 2 GO:0044464 - - "gi|148690678|gb|EDL22625.1|/1.82786e-47/mCG21152, partial [Mus musculus]" 19296 2805 0.376666667 0.35 -0.105933445 Down 0.105936666 Pvt1 plasmacytoma variant translocation 1 - - - - - 80838 745 0.14 0.12 -0.222392421 Down 0.105711008 Hist1h1a "histone cluster 1, H1a" K11275|1|1e-28|129|mmu:80838|histone H1/5 GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0003676//nucleic acid binding GO:0048232//male gamete generation;GO:0034728//nucleosome organization gi|21426823|ref|NP_085112.1|/7.74633e-28/histone H1.1 [Mus musculus] 29861 2278 0.113333333 0.133333333 0.234465254 Up 0.105711008 Dpf1 "D4, zinc and double PHD fingers family 1" K13196|1|0.0|785|mcc:719503|zinc finger protein ubi-d4 GO:0090544//BAF-type complex GO:0046914//transition metal ion binding "GO:0048731//system development;GO:0006351//transcription, DNA-templated" gi|7305309|ref|NP_038902.1|/0/zinc finger protein neuro-d4 [Mus musculus] 215303 2467 0.096666667 0.113333333 0.229481846 Up 0.105711008 Camk1g calcium/calmodulin-dependent protein kinase I gamma K08794|1|0.0|943|mmu:215303|calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0042995//cell projection;GO:0016020//membrane GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding GO:0019932//second-messenger-mediated signaling;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process gi|21450191|ref|NP_659066.1|/0/calcium/calmodulin-dependent protein kinase type 1G [Mus musculus] 11553 3214 0.136666667 0.116666667 -0.228268988 Down 0.105711008 Adra2c "adrenergic receptor, alpha 2c" K04140|1|0.0|694|mmu:11553|adrenergic receptor alpha-2C GO:0033267;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane GO:0004936//alpha-adrenergic receptor activity;GO:0031690//adrenergic receptor binding;GO:0042802//identical protein binding;GO:1901338;GO:0046983//protein dimerization activity GO:0001775//cell activation;GO:0045986//negative regulation of smooth muscle contraction;GO:0019229//regulation of vasoconstriction;GO:0015980//energy derivation by oxidation of organic compounds;GO:0019233//sensory perception of pain;GO:0030073//insulin secretion;GO:0014060;GO:0030182//neuron differentiation;GO:0007599//hemostasis;GO:0044703;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0000187//activation of MAPK activity;GO:0014061//regulation of norepinephrine secretion gi|156766088|ref|NP_031444.2|/0/alpha-2C adrenergic receptor [Mus musculus] 214112 3295 0.116666667 0.1 -0.222392421 Down 0.105711008 Nipal4 NIPA-like domain containing 4 K19364|1|6e-60|235|chx:102186911|magnesium transporter NIPA1 GO:0031224//intrinsic component of membrane GO:0046873//metal ion transmembrane transporter activity GO:0070838//divalent metal ion transport gi|27369726|ref|NP_766112.1|/0/magnesium transporter NIPA4 [Mus musculus] 258463 936 0.113333333 0.096666667 -0.229481846 Down 0.105711008 Olfr1393 olfactory receptor 1393 K04257|1|2e-158|560|mmu:258463|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|33238936|ref|NP_666682.1|/1.60623e-157/olfactory receptor 1393 [Mus musculus] 70375 3439 0.143333333 0.123333333 -0.216811389 Down 0.105711008 Ica1l islet cell autoantigen 1-like K19864|1|0.0|795|mmu:70375|islet cell autoantigen 1-like protein - - - - 240047 3564 0.096666667 0.113333333 0.229481846 Up 0.105711008 Mmp25 matrix metallopeptidase 25 K08003|1|0.0|745|mmu:240047|matrix metalloproteinase-25 (membrane-inserted) [EC:3.4.24.-] GO:0031012//extracellular matrix;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464 "GO:0008047//enzyme activator activity;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0008047//enzyme activator activity;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0006952//defense response;GO:0051345//positive regulation of hydrolase activity;GO:0044767//single-organism developmental process;GO:0019538//protein metabolic process;GO:0051345//positive regulation of hydrolase activity;GO:0044767//single-organism developmental process gi|75677470|ref|NP_001028511.1|/0/matrix metalloproteinase-25 isoform 1 precursor [Mus musculus] 319387 5812 0.156666667 0.133333333 -0.232660757 Down 0.105711008 Adgrl3 adhesion G protein-coupled receptor L3 K04594|1|0.0|2890|mmu:319387|latrophilin 3 GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity GO:0007186//G-protein coupled receptor signaling pathway gi|58037543|ref|NP_941991.1|/0/adhesion G protein-coupled receptor L3 precursor [Mus musculus] 67991 6385.8 7.57 7.683333333 0.021439045 Up 0.10540073 Nacc2 "nucleus accumbens associated 2, BEN and BTB (POZ) domain containing" K10486|1|0.0|1112|mmu:67991|BTB/POZ domain-containing protein 14 GO:0000118//histone deacetylase complex;GO:0000118//histone deacetylase complex "GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0042802//identical protein binding;GO:0019899//enzyme binding;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000989//transcription factor activity, transcription factor binding;GO:0042802//identical protein binding;GO:0019899//enzyme binding" GO:0031503//protein complex localization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006476//protein deacetylation;GO:0006974//cellular response to DNA damage stimulus;GO:0008283//cell proliferation;GO:0031503//protein complex localization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006476//protein deacetylation;GO:0006974//cellular response to DNA damage stimulus;GO:0008283//cell proliferation gi|80861477|ref|NP_001032175.1|/0/nucleus accumbens-associated protein 2 isoform 2 [Mus musculus] 109359 2895 9.096666667 8.983333333 -0.018087122 Down 0.10540073 Fam175b "family with sequence similarity 175, member B" - - - - - 75516 1000 10.11333333 10.22 0.015136611 Up 0.10540073 Ttc32 tetratricopeptide repeat domain 32 K09667|1|2e-06|55.5|tad:TRIADDRAFT_56833|protein O-GlcNAc transferase [EC:2.4.1.255] - - - - 26895 2231 6.153333333 6.26 0.02479451 Up 0.10540073 Cops7b COP9 signalosome subunit 7B K12180|1|3e-169|537|rno:363273|COP9 signalosome complex subunit 7 - - - - 94045 2293 10.28333333 10.17666667 -0.0150429 Down 0.10540073 P2rx5 "purinergic receptor P2X, ligand-gated ion channel, 5" K05219|1|0.0|884|mmu:94045|P2X purinoceptor 5 - - - gi|238624118|ref|NP_201578.2|/0/P2X purinoceptor 5 [Mus musculus] 69737 4562 7.423333333 7.533333333 0.021221215 Up 0.10540073 Ttl tubulin tyrosine ligase K06047|1|0.0|736|mmu:69737|tubulin---tyrosine ligase [EC:6.3.2.25] GO:0015630//microtubule cytoskeleton GO:0032550;GO:0016881//acid-amino acid ligase activity GO:0048638//regulation of developmental growth;GO:0007010//cytoskeleton organization;GO:0036211//protein modification process gi|28076929|ref|NP_081468.1|/0/tubulin--tyrosine ligase [Mus musculus] 192187 7995 10.26 10.15 -0.015551004 Down 0.10540073 Stab1 stabilin 1 K19020|1|0.0|5404|mmu:192187|stabilin-1 GO:0016021//integral component of membrane;GO:0044424 GO:0071813//lipoprotein particle binding;GO:0038024//cargo receptor activity;GO:0005539//glycosaminoglycan binding GO:0006952//defense response;GO:0001525//angiogenesis;GO:0022610;GO:0007154//cell communication gi|154240684|ref|NP_619613.2|/0/stabilin-1 precursor [Mus musculus] 27052 2923 0.423333333 0.453333333 0.098778154 Up 0.105231487 Aoah acyloxyacyl hydrolase K01065|1|0.0|1173|mmu:27052|acyloxyacyl hydrolase [EC:3.1.1.77] - GO:0052689//carboxylic ester hydrolase activity;GO:0052689//carboxylic ester hydrolase activity GO:0006954//inflammatory response;GO:0044255//cellular lipid metabolic process;GO:0006954//inflammatory response;GO:0044255//cellular lipid metabolic process gi|6753064|ref|NP_036184.1|/0/acyloxyacyl hydrolase isoform 1 preproprotein [Mus musculus] 72371 4096.22 0.45 0.483333333 0.103093493 Up 0.105231487 2210408I21Rik RIKEN cDNA 2210408I21 gene - - - - gi|224589075|ref|NP_001139148.1|/0/uncharacterized protein KIAA0825 homolog isoform 1 [Mus musculus] 78878 4292.02 0.413333333 0.443333333 0.101086125 Up 0.105231487 Ftx "Ftx transcript, Xist regulator (non-protein coding)" - - - - - 54357 2966 0.416666667 0.39 -0.095419565 Down 0.105231487 Epb41l4b erythrocyte membrane protein band 4.1 like 4b K06107|1|3e-74|283|fab:101821182|erythrocyte membrane protein band 4.1 GO:0044425;GO:0043232 GO:0005515//protein binding GO:0030036//actin cytoskeleton organization gi|169234799|ref|NP_062300.2|/0/band 4.1-like protein 4B [Mus musculus] 20264 6413.42 0.456666667 0.49 0.101640262 Up 0.105231487 Scn10a "sodium channel, voltage-gated, type X, alpha" K04842|1|0.0|3565|mmu:20264|voltage-gated sodium channel type X alpha - - - - 102941 2630 0.413333333 0.443333333 0.101086125 Up 0.105231487 B630019K06Rik novel protein similar to F-box and leucine-rich repeat protein 17 (Fbxl17) K10283|1|2e-60|236|mmu:50758|F-box and leucine-rich repeat protein 17 - - - gi|33416495|gb|AAH55780.1|/1.7012e-128/RIKEN cDNA B630019K06 gene [Mus musculus] 30049 3470 0.486666667 0.453333333 -0.102361718 Down 0.105231487 Scd3 stearoyl-coenzyme A desaturase 3 K00507|1|0.0|714|mmu:30049|stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1] GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0046914//transition metal ion binding;GO:0016215//acyl-CoA desaturase activity GO:0006631//fatty acid metabolic process;GO:0010872//regulation of cholesterol esterification;GO:0042742//defense response to bacterium;GO:0044126;GO:0045444//fat cell differentiation gi|13277368|ref|NP_077770.1|/0/acyl-CoA desaturase 3 [Mus musculus] 380921 3967 0.383333333 0.356666667 -0.104023065 Down 0.105231487 Dgkh "diacylglycerol kinase, eta" K00901|1|0.0|1170|mmu:380921|diacylglycerol kinase (ATP) [EC:2.7.1.107] - - - - 433091 4483 0.416666667 0.39 -0.095419565 Down 0.105231487 Pnpla1 patatin-like phospholipase domain containing 1 K16813|1|0.0|1106|mmu:433091|patatin-like phospholipase domain-containing protein 1 [EC:3.1.1.-] - GO:0003824//catalytic activity GO:0006629//lipid metabolic process gi|85702232|ref|NP_001030057.1|/0/patatin-like phospholipase domain-containing protein 1 [Mus musculus] 71101 7343 0.39 0.363333333 -0.102180395 Down 0.105231487 Uvssa UV stimulated scaffold protein A - - - - - 13116 2146 0.39 0.416666667 0.095419565 Up 0.105231487 Cyp46a1 "cytochrome P450, family 46, subfamily a, polypeptide 1" K07440|1|0.0|928|mmu:13116|cholesterol 24-hydroxylase [EC:1.14.14.25] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen" GO:0016125//sterol metabolic process "gi|148686768|gb|EDL18715.1|/0/cytochrome P450, family 46, subfamily a, polypeptide 1, isoform CRA_a, partial [Mus musculus]" 72054 1702 0.436666667 0.466666667 0.095860015 Up 0.105231487 Cyp4f18 "cytochrome P450, family 4, subfamily f, polypeptide 18" K17726|1|0.0|1035|mmu:72054|leukotriene-B4 20-monooxygenase / phylloquinone omega-hydroxylase [EC:1.14.13.30 1.14.13.194] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0044459 GO:0052870//tocopherol omega-hydroxylase activity;GO:0046914//transition metal ion binding;GO:0016713;GO:0046906//tetrapyrrole binding;GO:0016900;GO:0008391//arachidonic acid monooxygenase activity GO:0032303;GO:0055065//metal ion homeostasis;GO:0042362//fat-soluble vitamin biosynthetic process;GO:0036100;GO:0001977;GO:0007596//blood coagulation;GO:0019369//arachidonic acid metabolic process gi|251823870|ref|NP_077764.2|/0/leukotriene-B(4) omega-hydroxylase 2 precursor [Mus musculus] 105203 8356 0.483333333 0.516666667 0.096215315 Up 0.105231487 Fam208b "family with sequence similarity 208, member B" - - - - gi|60360466|dbj|BAD90477.1|/0/mKIAA2006 protein [Mus musculus] 217217 1362 0.433333333 0.463333333 0.09657326 Up 0.105231487 Asb16 ankyrin repeat and SOCS box-containing 16 K10338|1|0.0|848|mmu:217217|ankyrin repeat and SOCS box protein 16 - - GO:0007165//signal transduction gi|22507369|ref|NP_683755.1|/0/ankyrin repeat and SOCS box protein 16 [Mus musculus] 11429 2785 1521.906667 1506.533333 -0.014647292 Down 0.105024634 Aco2 "aconitase 2, mitochondrial" K01681|1|0.0|1559|ocu:100352714|aconitate hydratase [EC:4.2.1.3] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0051536//iron-sulfur cluster binding;GO:0003994//aconitate hydratase activity GO:0009060//aerobic respiration;GO:0072350//tricarboxylic acid metabolic process "gi|958777144|ref|XP_014719872.1|/0/PREDICTED: aconitate hydratase, mitochondrial [Equus asinus]" 12857 759.99 1681.153333 1690.793333 0.008249014 Up 0.104958818 Cox4i1 cytochrome c oxidase subunit IV isoform 1 K02263|1|1e-94|347|mmu:12857|cytochrome c oxidase subunit 4 GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0044710;GO:0031667//response to nutrient levels;GO:0044710;GO:0031667//response to nutrient levels "gi|148679695|gb|EDL11642.1|/7.5149e-101/cytochrome c oxidase subunit IV isoform 1, isoform CRA_a, partial [Mus musculus]" 17992 492 1389.6 1398.83 0.009550983 Up 0.104940013 Ndufa4 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4" K03948|1|5e-43|175|rno:681024|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4 GO:0005746//mitochondrial respiratory chain GO:0015002//heme-copper terminal oxidase activity GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy gi|33563266|ref|NP_035016.1|/2.97513e-42/cytochrome c oxidase subunit NDUFA4 [Mus musculus] 17448 1297 959.7533333 968.3833333 0.012914584 Up 0.10493061 Mdh2 "malate dehydrogenase 2, NAD (mitochondrial)" K00026|1|3e-171|603|mmu:17448|malate dehydrogenase [EC:1.1.1.37] GO:0031981//nuclear lumen;GO:0019866//organelle inner membrane;GO:0044429 GO:0016615//malate dehydrogenase activity;GO:0005515//protein binding GO:0043648//dicarboxylic acid metabolic process;GO:0006473//protein acetylation;GO:0005975//carbohydrate metabolic process;GO:0009060//aerobic respiration;GO:0019674//NAD metabolic process "gi|31982186|ref|NP_032643.2|/2.74715e-170/malate dehydrogenase, mitochondrial precursor [Mus musculus]" 329427 2707 1.04 1 -0.056583528 Down 0.104921208 Chn1os3 "chimerin 1, opposite strand 3" - - GO:0005102//receptor binding GO:0007411//axon guidance;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|537152034|gb|ERE71961.1|/2.447e-13/cyclic AMP-dependent transcription factor ATF-2 isoform 1 [Cricetulus griseus] 240726 8526 0.936666667 0.9 -0.057610723 Down 0.104921208 Slco5a1 "solute carrier organic anion transporter family, member 5A1" "K14356|1|0.0|1574|mmu:240726|solute carrier organic anion transporter family, member 5A" - - - gi|124378011|ref|NP_766429.2|/0/solute carrier organic anion transporter family member 5A1 [Mus musculus] 19124 1504 0.926666667 0.89 -0.058245141 Down 0.104921208 Procr "protein C receptor, endothelial" "K06557|1|2e-119|432|mmu:19124|protein C receptor, endothelial (EPCR)" GO:0005815//microtubule organizing center;GO:0031224//intrinsic component of membrane GO:0005515//protein binding GO:0007599//hemostasis;GO:0050817//coagulation;GO:0002376//immune system process gi|251823822|ref|NP_035301.2|/1.3513e-118/endothelial protein C receptor precursor [Mus musculus] 100861615 1991 0.883333333 0.846666667 -0.061163863 Down 0.104921208 LOC100861615 alpha takusan-like "K03844|1|1e-18|97.8|cge:100765573|alpha-1,2-mannosyltransferase [EC:2.4.1.131]" - - - gi|755546841|ref|XP_011243026.1|/1.41932e-122/PREDICTED: predicted gene 3264 isoform X1 [Mus musculus] 78445 878 0.876666667 0.913333333 0.059113094 Up 0.104921208 C330013E15Rik RIKEN cDNA C330013E15 gene - - - - - 268747 4620 0.976666667 1.016666667 0.057908578 Up 0.104921208 Lrrc16b leucine rich repeat containing 16B K20493|1|0.0|2334|mmu:268747|leucine-rich repeat-containing protein 16 - - - gi|66912205|ref|NP_001019816.1|/0/leucine-rich repeat-containing protein 16B [Mus musculus] 67724 3303 0.876666667 0.913333333 0.059113094 Up 0.104921208 Pop1 "processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)" K01164|1|0.0|1979|mmu:67724|ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5] GO:0005732//small nucleolar ribonucleoprotein complex;GO:0030681//multimeric ribonuclease P complex;GO:0005732//small nucleolar ribonucleoprotein complex;GO:0030681//multimeric ribonuclease P complex GO:0004549//tRNA-specific ribonuclease activity;GO:0005488//binding;GO:0004549//tRNA-specific ribonuclease activity GO:0008033//tRNA processing;GO:0008033//tRNA processing gi|23097256|ref|NP_690854.1|/0/ribonucleases P/MRP protein subunit POP1 isoform 1 [Mus musculus] 11957 593.28 713.67 707.42 -0.012690121 Down 0.104902403 Atp5j "ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F" K02131|1|2e-48|193|mmu:11957|F-type H+-transporting ATPase subunit 6 "GO:0005743//mitochondrial inner membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0005743//mitochondrial inner membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0005743//mitochondrial inner membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0005743//mitochondrial inner membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0005743//mitochondrial inner membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain" GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0009154//purine ribonucleotide catabolic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0009154//purine ribonucleotide catabolic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0009154//purine ribonucleotide catabolic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0009154//purine ribonucleotide catabolic process;GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0009154//purine ribonucleotide catabolic process "gi|148665899|gb|EDK98315.1|/1.30978e-56/ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F, isoform CRA_b, partial [Mus musculus]" 66477 370 1196.223333 1189.876667 -0.007674721 Down 0.104902403 Usmg5 upregulated during skeletal muscle growth 5 K18194|1|1e-26|120|mmu:66477|up-regulated during skeletal muscle growth protein 5 GO:0005743//mitochondrial inner membrane;GO:0031224//intrinsic component of membrane - - gi|9843791|emb|CAC03620.1|/2.53254e-30/stretch regulated skeletal muscle protein [Mus musculus] 11958 356 715.9533333 710.65 -0.010726356 Down 0.104874196 Atp5k "ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit E" K02129|1|1e-24|113|mmu:11958|F-type H+-transporting ATPase subunit e "GO:0005743//mitochondrial inner membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain" GO:0017111//nucleoside-triphosphatase activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity GO:0006818//hydrogen transport;GO:0006754//ATP biosynthetic process;GO:0009154//purine ribonucleotide catabolic process "gi|83715998|ref|NP_031533.2|/1.35871e-23/ATP synthase subunit e, mitochondrial [Mus musculus]" 15464 2443 611.2266667 606.5633333 -0.011049197 Down 0.104836587 Hrc histidine rich calcium binding protein "K06706|1|1e-49|200|ocu:103347265|CD248 antigen, endosialin;K19991|2|6e-06|55.8|asn:102376578|chromogranin-B" GO:0005789//endoplasmic reticulum membrane GO:0019899//enzyme binding GO:0055065//metal ion homeostasis gi|133778931|ref|NP_034603.2|/0/sarcoplasmic reticulum histidine-rich calcium-binding protein precursor [Mus musculus] 14467 2115 334.3466667 331.6566667 -0.011654208 Down 0.104639136 Gbas glioblastoma amplified sequence K02D10.1;|1|4e-47|192|cel:CELE_K02D10.1|Putative NipSnap protein K02D10.1;K19269|1|4e-47|192|cel:CELE_K02D10.1|phosphoglycolate phosphatase [EC:3.1.3.18 3.1.3.48];K13174|3|2e-15|87.0|aam:106485346|THO complex subunit 5 GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane GO:0005488//binding GO:0009152//purine ribonucleotide biosynthetic process;GO:0006091//generation of precursor metabolites and energy;GO:0051348//negative regulation of transferase activity gi|160298168|ref|NP_032121.3|/2.52048e-156/protein NipSnap homolog 2 [Mus musculus] 14718 2065 687.61 690.38 0.005800145 Up 0.104639136 Got1 "glutamic-oxaloacetic transaminase 1, soluble" "K14454|1|0.0|844|mmu:14718|aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]" GO:0000323//lytic vacuole;GO:0033267 GO:0043168//anion binding;GO:0016831//carboxy-lyase activity;GO:0070546 GO:0006071//glycerol metabolic process;GO:0032868//response to insulin;GO:0009064//glutamine family amino acid metabolic process;GO:0006531//aspartate metabolic process;GO:0055081//anion homeostasis;GO:0031960//response to corticosteroid;GO:0006103//2-oxoglutarate metabolic process "gi|160298209|ref|NP_034454.2|/0/aspartate aminotransferase, cytoplasmic [Mus musculus]" 232406 2612 0.15 0.173333333 0.208586622 Up 0.104592125 BC035044 cDNA sequence BC035044 - - - - gi|363807246|ref|NP_001241875.1|/1.26872e-75/uncharacterized protein LOC232406 isoform 1 [Mus musculus] 210297 3616 0.15 0.13 -0.206450877 Down 0.104592125 Lrch2 leucine-rich repeats and calponin homology (CH) domain containing 2 K19613|1|1e-18|98.6|bfo:BRAFLDRAFT_214464|leucine-rich repeat protein SHOC2 - - - gi|124487175|ref|NP_001074642.1|/0/leucine-rich repeat and calponin homology domain-containing protein 2 [Mus musculus] 15006 2044 0.106666667 0.123333333 0.209453366 Up 0.104592125 H2-Q1 "histocompatibility 2, Q region locus 1" "K06751|1|0.0|664|mmu:15006|major histocompatibility complex, class I" GO:0031224//intrinsic component of membrane;GO:0042611;GO:0009986//cell surface GO:0005515//protein binding GO:0002484;GO:0002664//regulation of T cell tolerance induction;GO:0009581;GO:0001817//regulation of cytokine production "gi|160333390|ref|NP_034520.2|/0/histocompatibility 2, Q region locus 1 precursor [Mus musculus]" 22410 2272 0.106666667 0.123333333 0.209453366 Up 0.104592125 Wnt10b "wingless-type MMTV integration site family, member 10B" "K01357|1|0.0|704|mmu:22410|wingless-type MMTV integration site family, member 10" - - - gi|532078357|ref|XP_005324955.1|/0/PREDICTED: protein Wnt-10b [Ictidomys tridecemlineatus] 74023 3650 0.106666667 0.123333333 0.209453366 Up 0.104592125 Rd3 retinal degeneration 3 - - - GO:0043010//camera-type eye development;GO:0043010//camera-type eye development;GO:0043010//camera-type eye development "gi|148681027|gb|EDL12974.1|/3.71951e-148/RIKEN cDNA 3322402L07, isoform CRA_b, partial [Mus musculus]" 74424 3774 0.15 0.173333333 0.208586622 Up 0.104592125 Tmc5 transmembrane channel-like gene family 5 K10877|1|5e-12|76.3|tsp:Tsp_10860|DNA repair and recombination protein RAD54B [EC:3.6.4.-] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148685186|gb|EDL17133.1|/0/transmembrane channel-like gene family 5, isoform CRA_a [Mus musculus]" 77132 1334 0.123333333 0.106666667 -0.209453366 Down 0.104592125 2810433D01Rik RIKEN cDNA 2810433D01 gene - - - - - 192651 3006 0.13 0.15 0.206450877 Up 0.104592125 Zfp286 zinc finger protein 286 K09228|1|0.0|1092|mmu:192651|KRAB domain-containing zinc finger protein - - - gi|31543186|ref|NP_620399.3|/0/zinc finger protein 286A [Mus musculus] 20728 1266 0.13 0.15 0.206450877 Up 0.104592125 Spic Spi-C transcription factor (Spi-1/PU.1 related) K09440|1|5e-130|466|mmu:20728|transcription factor Spi-C GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006366//transcription from RNA polymerase II promoter gi|165932335|ref|NP_035591.3|/3.85933e-129/transcription factor Spi-C [Mus musculus] 12759 1832 515.7466667 517.93 0.006094534 Up 0.104554515 Clu clusterin K17252|1|0.0|852|mmu:12759|clusterin - - - - 22065 3694 1.9 1.953333333 0.039938745 Up 0.104516905 Trpc3 "transient receptor potential cation channel, subfamily C, member 3" K04966|1|0.0|1668|mmu:22065|transient receptor potential cation channel subfamily C member 3 GO:0031224//intrinsic component of membrane GO:0043168//anion binding;GO:0005261//cation channel activity GO:0010038//response to metal ion;GO:0046683//response to organophosphorus;GO:0010522//regulation of calcium ion transport into cytosol gi|170650611|ref|NP_062383.2|/0/short transient receptor potential channel 3 [Mus musculus] 66812 2767 1.816666667 1.87 0.041744541 Up 0.104516905 Ppcdc phosphopantothenoylcysteine decarboxylase K01598|1|2e-104|382|mmu:66812|phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36] - GO:0016831//carboxy-lyase activity GO:0009108//coenzyme biosynthetic process gi|28849879|ref|NP_789801.1|/2.00606e-103/phosphopantothenoylcysteine decarboxylase [Mus musculus] 110902 3527 1.766666667 1.82 0.042908591 Up 0.104516905 Chrna2 "cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)" K04804|1|0.0|997|mmu:110902|nicotinic acetylcholine receptor alpha-2 GO:0097060//synaptic membrane;GO:0005887//integral component of plasma membrane GO:0004888//transmembrane signaling receptor activity;GO:0042165//neurotransmitter binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0051259//protein oligomerization;GO:0044765//single-organism transport;GO:0007154//cell communication "gi|149030324|gb|EDL85380.1|/0/cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), isoform CRA_b [Rattus norvegicus]" 68187 6467 1.986666667 2.036666667 0.035860049 Up 0.104516905 Fam135a "family with sequence similarity 135, member A" - - - - gi|229577388|ref|NP_080880.4|/0/protein FAM135A [Mus musculus] 227446 5423.99 1.73 1.783333333 0.043804353 Up 0.104516905 2310035C23Rik RIKEN cDNA 2310035C23 gene - - - - gi|170014746|ref|NP_083625.1|/0/lisH domain and HEAT repeat-containing protein KIAA1468 isoform 2 [Mus musculus] 100038712 2612 1.703333333 1.753333333 0.041739508 Up 0.104516905 Gm10516 predicted gene 10516 - - - - gi|74216356|dbj|BAE25119.1|/1.27462e-59/unnamed protein product [Mus musculus] 71069 9382.46 1.843333333 1.796666667 -0.036994207 Down 0.104516905 Stox2 storkhead box 2 - - - GO:0007275//multicellular organism development;GO:0007275//multicellular organism development;GO:0007275//multicellular organism development gi|166851842|ref|NP_001107783.1|/0/storkhead-box protein 2 isoform 1 [Mus musculus] 277939 7813 1.656666667 1.61 -0.041222663 Down 0.104516905 C2cd3 C2 calcium-dependent domain containing 3 K16751|1|0.0|4360|mmu:277939|C2 domain-containing protein 3 - - - gi|125347500|ref|NP_001017985.2|/0/C2 domain-containing protein 3 [Mus musculus] 233168 2791.84 1.633333333 1.683333333 0.043501639 Up 0.104516905 AI987944 expressed sequence AI987944 K09228|1|0.0|852|mmu:233168|KRAB domain-containing zinc finger protein - - - - 74735 3204 2.023333333 1.97 -0.038538386 Down 0.104516905 Trim14 tripartite motif-containing 14 K12004|1|0.0|824|mmu:74735|tripartite motif-containing protein 14 - - - - 66202 3361 1.893333333 1.946666667 0.040077439 Up 0.104516905 1110059G10Rik RIKEN cDNA 1110059G10 gene K10400|1|2e-10|71.2|shr:105750752|kinesin family member 15 - - - gi|31541808|ref|NP_079695.2|/7.86443e-81/uncharacterized protein KIAA1143 homolog [Mus musculus] 75712 1190 1.523333333 1.57 0.043532895 Up 0.104516905 Tmem14a transmembrane protein 14A - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|568905499|ref|XP_006495642.1|/1.62824e-75/PREDICTED: transmembrane protein 14A isoform X1 [Mus musculus] 12180 3364.66 242.8233333 240.9233333 -0.011332935 Down 0.104432284 Smyd1 SET and MYND domain containing 1 K11426|1|0.0|978|mmu:12180|SET and MYND domain-containing protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity "GO:0006351//transcription, DNA-templated;GO:0045445//myoblast differentiation;GO:0010830//regulation of myotube differentiation;GO:0016568//chromatin modification;GO:0006351//transcription, DNA-templated;GO:0045445//myoblast differentiation;GO:0010830//regulation of myotube differentiation;GO:0016568//chromatin modification" gi|236461142|ref|NP_033892.2|/0/histone-lysine N-methyltransferase Smyd1 isoform 2 [Mus musculus] 93887 5278 0.113333333 0.13 0.197939378 Up 0.104394674 Pcdhb16 protocadherin beta 16 K16494|1|0.0|1473|mmu:93887|protocadherin beta - - - - 73314 1210 0.13 0.113333333 -0.197939378 Down 0.104394674 Lrrc69 leucine rich repeat containing 69 K18342|1|3e-40|168|umr:103661421|OTU domain-containing protein 6 [EC:3.4.19.12];K16175|2|2e-20|102|mgp:100544129|protein scribble - - - gi|568927465|ref|XP_006538358.1|/1.45396e-178/PREDICTED: leucine-rich repeat-containing protein 69 isoform X1 [Mus musculus] 16572 6334 0.16 0.183333333 0.196397213 Up 0.104394674 Kif5a kinesin family member 5A K10396|1|0.0|1826|mmu:16572|kinesin family member 5 GO:0005875//microtubule associated complex;GO:0030424//axon;GO:0044297//cell body;GO:0044444//cytoplasmic part;GO:0005875//microtubule associated complex;GO:0030424//axon;GO:0044297//cell body;GO:0044444//cytoplasmic part GO:0032550;GO:0003774//motor activity;GO:0015631//tubulin binding;GO:0032550;GO:0003774//motor activity;GO:0015631//tubulin binding GO:0007267//cell-cell signaling;GO:0002478;GO:0006928//movement of cell or subcellular component;GO:0007599//hemostasis;GO:0007267//cell-cell signaling;GO:0002478;GO:0006928//movement of cell or subcellular component;GO:0007599//hemostasis gi|60360518|dbj|BAD90503.1|/0/mKIAA4086 protein [Mus musculus] 20420 1548 0.19 0.166666667 -0.189033824 Down 0.104394674 Shd src homology 2 domain-containing transforming protein D K19862|1|3e-09|65.9|hmg:100201881|NCK adaptor protein 2;K07293|3|1e-08|63.9|hmg:100210713|tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48];K06619|4|2e-08|63.5|dwi:Dwil_GK20085|abelson tyrosine-protein kinase 1 [EC:2.7.10.2] - - - gi|6677939|ref|NP_033194.1|/0/SH2 domain-containing adapter protein D isoform 2 [Mus musculus] 330149 1438 0.163333333 0.143333333 -0.188445089 Down 0.104394674 Hfm1 "HFM1, ATP-dependent DNA helicase homolog" K15271|1|0.0|2826|mmu:330149|ATP-dependent DNA helicase HFM1/MER3 [EC:3.6.4.12] - - - - 595136 540 356.3233333 358.1566667 0.007403837 Up 0.104394674 Ndufs5 NADH dehydrogenase (ubiquinone) Fe-S protein 5 K03938|1|2e-59|230|mmu:595136|NADH dehydrogenase (ubiquinone) Fe-S protein 5 GO:0005746//mitochondrial respiratory chain - GO:0010257//NADH dehydrogenase complex assembly;GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy "gi|148698428|gb|EDL30375.1|/5.49124e-63/mCG5769, isoform CRA_b, partial [Mus musculus]" 13828 3920 0.143333333 0.163333333 0.188445089 Up 0.104394674 Epb42 erythrocyte membrane protein band 4.2 K05622|1|0.0|961|aml:100468973|transglutaminase 5 [EC:2.3.2.13];K05625|2|4e-106|389|cjo:107323089|transglutaminase 2 [EC:2.3.2.13] - - - - 77630 3119 0.193333333 0.17 -0.185555653 Down 0.104394674 Prdm8 PR domain containing 8 K16660|1|5e-23|112|dgr:Dgri_GH14523|reticulon-4 receptor-like 1;K12463|2|1e-06|58.5|tru:101079614|PR domain zinc finger protein 4 GO:0043231//intracellular membrane-bounded organelle;GO:0034708 GO:0018024//histone-lysine N-methyltransferase activity;GO:0003712//transcription cofactor activity;GO:0046872//metal ion binding "GO:0006351//transcription, DNA-templated;GO:0021952//central nervous system projection neuron axonogenesis;GO:0034968//histone lysine methylation" gi|110347527|ref|NP_084223.2|/0/PR domain zinc finger protein 8 [Mus musculus] 16922 1474 427.3566667 429.1066667 0.005895687 Up 0.10437587 Phyh phytanoyl-CoA hydroxylase K00477|1|0.0|703|mmu:16922|phytanoyl-CoA hydroxylase [EC:1.14.11.18] GO:0042579//microbody "GO:0043169//cation binding;GO:0019842//vitamin binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0009062//fatty acid catabolic process "gi|6754564|ref|NP_034856.1|/0/phytanoyl-CoA dioxygenase, peroxisomal precursor [Mus musculus]" 269966 6458.1 6.37 6.466666667 0.021728874 Up 0.104244236 Nup98 nucleoporin 98 K14297|1|0.0|1873|mmu:269966|nuclear pore complex protein Nup98-Nup96 "GO:0031981//nuclear lumen;GO:0005643//nuclear pore;GO:0000775//chromosome, centromeric region;GO:0016234//inclusion body;GO:0031981//nuclear lumen;GO:0005643//nuclear pore;GO:0000775//chromosome, centromeric region;GO:0016234//inclusion body;GO:0031981//nuclear lumen;GO:0005643//nuclear pore;GO:0016234//inclusion body;GO:0031981//nuclear lumen;GO:0005643//nuclear pore;GO:0000775//chromosome, centromeric region;GO:0016234//inclusion body" GO:0033218//amide binding;GO:0005198//structural molecule activity;GO:0033218//amide binding;GO:0005198//structural molecule activity;GO:0033218//amide binding;GO:0005198//structural molecule activity;GO:0033218//amide binding;GO:0005198//structural molecule activity GO:0006999//nuclear pore organization;GO:0006259//DNA metabolic process;GO:0050658//RNA transport;GO:0006999//nuclear pore organization;GO:0006259//DNA metabolic process;GO:0050658//RNA transport;GO:0006999//nuclear pore organization;GO:0006259//DNA metabolic process;GO:0006999//nuclear pore organization;GO:0006259//DNA metabolic process;GO:0050658//RNA transport "gi|148684636|gb|EDL16583.1|/0/nucleoporin 98, isoform CRA_b, partial [Mus musculus]" 78252 3368 0.42 0.446666667 0.088809267 Up 0.104244236 Nxpe2 "neurexophilin and PC-esterase domain family, member 2" "K02324|1|1e-26|125|sko:100367259|DNA polymerase epsilon subunit 1 [EC:2.7.7.7];K15010|2|4e-23|113|xma:102227992|homer;K07422|3|2e-11|74.7|bfo:BRAFLDRAFT_72966|cytochrome P450, family 2, subfamily U, polypeptide 1" GO:0031224//intrinsic component of membrane - - gi|160333214|ref|NP_084345.2|/0/NXPE family member 2 [Mus musculus] 68178 6797.25 7.123333333 7.02 -0.021081472 Down 0.104244236 Cgnl1 cingulin-like 1 K06102|1|4e-134|483|pss:102453795|cingulin GO:0043296//apical junction complex;GO:0015629//actin cytoskeleton GO:0017111//nucleoside-triphosphatase activity - gi|56550079|ref|NP_080875.3|/0/cingulin-like protein 1 [Mus musculus] 56546 2470 0.46 0.49 0.091147888 Up 0.104244236 Sec1 secretory blood group 1 K00718|1|0.0|815|mmu:56546|galactoside 2-L-fucosyltransferase 1/2 [EC:2.4.1.69] GO:0031224//intrinsic component of membrane "GO:0031127//alpha-(1,2)-fucosyltransferase activity" GO:0006464//cellular protein modification process;GO:0070085//glycosylation gi|409191586|ref|NP_001258507.1|/0/galactoside 2-alpha-L-fucosyltransferase 3 [Mus musculus] 232187 2507 6.41 6.51 0.022333187 Up 0.104244236 Smyd5 SET and MYND domain containing 5 K11426|1|4e-08|63.2|nve:NEMVE_v1g214071|SET and MYND domain-containing protein - GO:0043169//cation binding - gi|154689581|ref|NP_659167.2|/0/SET and MYND domain-containing protein 5 [Mus musculus] 224674 3362 7.013333333 7.11 0.019749261 Up 0.104244236 Slc37a1 "solute carrier family 37 (glycerol-3-phosphate transporter), member 1" "K13783|1|0.0|1033|mmu:224674|MFS transporter, OPA family, solute carrier family 37 (glycerol-3-phosphate transporter), member 1/2" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763 gi|23346457|ref|NP_694702.1|/0/glycerol-3-phosphate transporter [Mus musculus] 74522 4787.86 6.216666667 6.316666667 0.023022218 Up 0.104244236 Morc2a microrchidia 2A - - GO:0046914//transition metal ion binding - gi|50510669|dbj|BAD32320.1|/0/mKIAA0852 protein [Mus musculus] 17079 2326 0.423333333 0.396666667 -0.093866923 Down 0.104244236 Cd180 CD180 antigen K06555|1|0.0|1179|mmu:17079|CD180 antigen GO:0031224//intrinsic component of membrane - GO:0006952//defense response;GO:0002833;GO:0032496//response to lipopolysaccharide gi|117320545|ref|NP_032559.2|/0/CD180 antigen precursor [Mus musculus] 109032 1924.6 6.473333333 6.573333333 0.022116351 Up 0.104244236 Sp110 Sp110 nuclear body protein K15413|1|3e-24|116|phd:102344064|nuclear autoantigen Sp-100 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - "GO:0012502//induction of programmed cell death;GO:0006952//defense response;GO:0051707//response to other organism;GO:0006351//transcription, DNA-templated;GO:0012502//induction of programmed cell death;GO:0006952//defense response;GO:0051707//response to other organism;GO:0006351//transcription, DNA-templated" gi|133893022|ref|NP_780606.3|/0/sp110 nuclear body protein [Mus musculus] 66306 4475 6.116666667 6.013333333 -0.024580724 Down 0.104244236 Fam53c "family with sequence similarity 53, member C" K15601|1|1e-09|68.9|chx:102184056|lysine-specific demethylase 3 [EC:1.14.11.-];K18710|2|4e-06|57.4|asn:102384143|histone RNA hairpin-binding protein - - - "gi|148664700|gb|EDK97116.1|/1.19535e-180/RIKEN cDNA 2810012G03, isoform CRA_b, partial [Mus musculus]" 27354 2491 8.546666667 8.446666667 -0.016979737 Down 0.104244236 Nbn nibrin K10867|1|0.0|1463|mmu:27354|nijmegen breakage syndrome protein 1 "GO:0031981//nuclear lumen;GO:0000781//chromosome, telomeric region;GO:0016234//inclusion body;GO:0043234//protein complex" GO:0005515//protein binding;GO:0003677//DNA binding;GO:0003678//DNA helicase activity GO:0001934//positive regulation of protein phosphorylation;GO:0042221//response to chemical;GO:0007127//meiosis I;GO:0042127//regulation of cell proliferation;GO:0012501//programmed cell death;GO:0031572//G2 DNA damage checkpoint;GO:0043549//regulation of kinase activity;GO:0001824//blastocyst development;GO:0002204//somatic recombination of immunoglobulin genes involved in immune response;GO:0050905//neuromuscular process;GO:0032392//DNA geometric change;GO:0006281//DNA repair;GO:0030182//neuron differentiation gi|145386524|ref|NP_038780.3|/0/nibrin [Mus musculus] 212999 4866 7.926666667 8.026666667 0.018086677 Up 0.104244236 Tnpo2 "transportin 2 (importin 3, karyopherin beta 2b)" K18727|1|0.0|1724|ngi:103751888|transportin-2 GO:0005635//nuclear envelope;GO:0005635//nuclear envelope GO:0005048//signal sequence binding;GO:0022892//substrate-specific transporter activity;GO:0005048//signal sequence binding;GO:0022892//substrate-specific transporter activity GO:0015031//protein transport;GO:0015031//protein transport gi|694973160|ref|XP_009433054.1|/0/PREDICTED: transportin-2 isoform X3 [Pan troglodytes] 227715 1635 6.076666667 6.176666667 0.02354832 Up 0.104244236 Exosc2 exosome component 2 K03679|1|4e-163|577|mmu:227715|exosome complex component RRP4 GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding GO:0016049//cell growth;GO:0042254//ribosome biogenesis gi|21450259|ref|NP_659135.1|/3.79784e-162/exosome complex component RRP4 [Mus musculus] 320088 3135 0.413333333 0.44 0.090197809 Up 0.104244236 C030034L19Rik RIKEN cDNA C030034L19 gene - - - - - 64380 1723 0.473333333 0.503333333 0.08865762 Up 0.104244236 Ms4a4c "membrane-spanning 4-domains, subfamily A, member 4C" "K19928|1|2e-18|96.7|clv:102089886|zona pellucida sperm-binding protein 3;K08090|4|1e-10|70.9|bacu:103020959|membrane-spanning 4-domains, subfamily A, member 2" GO:0031224//intrinsic component of membrane - - "gi|13386406|ref|NP_083775.1|/7.73466e-121/membrane-spanning 4-domains, subfamily A, member 4C [Mus musculus]" 235330 3630 8.373333333 8.47 0.016559911 Up 0.104244236 Ttc12 tetratricopeptide repeat domain 12 K09553|1|8e-15|85.9|dmo:Dmoj_GI17037|stress-induced-phosphoprotein 1 - - - gi|27370132|ref|NP_766358.1|/0/tetratricopeptide repeat protein 12 [Mus musculus] 76500 1842 6.653333333 6.75 0.020810187 Up 0.104244236 Ip6k2 inositol hexaphosphate kinase 2 K07756|1|0.0|870|mmu:76500|inositol-hexakisphosphate 5-kinase [EC:2.7.4.21] - GO:0051766//inositol trisphosphate kinase activity - gi|225903432|ref|NP_083910.2|/0/inositol hexakisphosphate kinase 2 [Mus musculus] 97961 1993 6.113333333 6.21 0.022634035 Up 0.104244236 Nol12 nucleolar protein 12 K14851|1|5e-72|275|mmu:97961|ribosomal RNA-processing protein 17 GO:0031981//nuclear lumen GO:0003723//RNA binding - gi|31542287|ref|NP_598561.2|/3.97274e-71/nucleolar protein 12 [Mus musculus] 66075 1432 287.33 288.82 0.007462016 Up 0.104225432 Chchd3 coiled-coil-helix-coiled-coil-helix domain containing 3 "K17563|1|2e-109|398|mmu:66075|coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial" - - - - 59091 4229.69 190.2833333 191.7 0.010701134 Up 0.104169017 Jph2 junctophilin 2 K19530|1|0.0|915|mmu:59091|junctophilin GO:0033017//sarcoplasmic reticulum membrane;GO:0031674//I band;GO:0033017//sarcoplasmic reticulum membrane;GO:0031674//I band GO:0005262//calcium channel activity;GO:0005488//binding;GO:0005262//calcium channel activity;GO:0005488//binding GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0016202//regulation of striated muscle tissue development;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0016202//regulation of striated muscle tissue development gi|10947010|ref|NP_067541.1|/0/junctophilin-2 [Mus musculus] 233870 1718 172.9333333 174.1033333 0.009727846 Up 0.104009177 Tufm "Tu translation elongation factor, mitochondrial" K02358|1|0.0|822|mmu:233870|elongation factor Tu GO:0019866//organelle inner membrane;GO:0005759//mitochondrial matrix;GO:0019866//organelle inner membrane;GO:0005759//mitochondrial matrix "GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008135//translation factor activity, RNA binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008135//translation factor activity, RNA binding" GO:0006412//translation;GO:0006412//translation "gi|27370092|ref|NP_766333.1|/0/elongation factor Tu, mitochondrial isoform 1 [Mus musculus]" 56873 4949 2.453333333 2.396666667 -0.033713996 Down 0.103999774 Lmbr1 limb region 1 K00858|1|8e-16|89.7|smm:Smp_126160|NAD+ kinase [EC:2.7.1.23] GO:0031224//intrinsic component of membrane - GO:0030326//embryonic limb morphogenesis gi|45598379|ref|NP_064691.2|/0/limb region 1 protein [Mus musculus] 20539 3513 2.65 2.706666667 0.030524867 Up 0.103999774 Slc7a5 "solute carrier family 7 (cationic amino acid transporter, y+ system), member 5" "K13780|1|0.0|864|mmu:20539|solute carrier family 7 (L-type amino acid transporter), member 5" GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0003823//antigen binding;GO:0015171//amino acid transmembrane transporter activity GO:0048731//system development;GO:0006865//amino acid transport;GO:0048869//cellular developmental process gi|4519256|dbj|BAA75520.1|/0/4F2/CD98 light chain [Mus musculus] 100504703 329 2.66 2.723333333 0.033947332 Up 0.103999774 A730063M14Rik RIKEN cDNA A730063M14 gene - - - - - 110524 4612 3.013333333 3.073333333 0.028443978 Up 0.103999774 Dgkq "diacylglycerol kinase, theta" K00901|1|0.0|1824|mmu:110524|diacylglycerol kinase (ATP) [EC:2.7.1.107] GO:0016604//nuclear body;GO:0043232;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0043169//cation binding;GO:0032550;GO:0019899//enzyme binding;GO:0016301//kinase activity;GO:0008134//transcription factor binding GO:0046683//response to organophosphorus;GO:0006796//phosphate-containing compound metabolic process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0007186//G-protein coupled receptor signaling pathway gi|39841023|ref|NP_950176.1|/0/diacylglycerol kinase theta [Mus musculus] 20678 7079 2.856666667 2.793333333 -0.03234496 Down 0.103999774 Sox5 SRY (sex determining region Y)-box 5 K09269|1|0.0|1127|oas:101115356|transcription factor SOX5/6/13 (SOX group D) GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding GO:0071363//cellular response to growth factor stimulus;GO:0051094//positive regulation of developmental process;GO:0002062//chondrocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007417//central nervous system development;GO:0045664//regulation of neuron differentiation;GO:0072497;GO:0071363//cellular response to growth factor stimulus;GO:0051094//positive regulation of developmental process;GO:0002062//chondrocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007417//central nervous system development;GO:0045664//regulation of neuron differentiation;GO:0072497;GO:0071363//cellular response to growth factor stimulus;GO:0051094//positive regulation of developmental process;GO:0002062//chondrocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007417//central nervous system development;GO:0045664//regulation of neuron differentiation;GO:0072497 gi|165932306|ref|NP_035574.2|/0/transcription factor SOX-5 isoform a [Mus musculus] 320816 2356 2.943333333 2.886666667 -0.028046413 Down 0.103999774 Ankrd16 ankyrin repeat domain 16 K10380|1|1e-29|134|ola:101172448|ankyrin - - - gi|241982810|ref|NP_796242.2|/0/ankyrin repeat domain-containing protein 16 [Mus musculus] 226016 2475 2.373333333 2.316666667 -0.034864263 Down 0.103999774 Abhd17b abhydrolase domain containing 17B K06889|1|9e-15|85.1|pxy:105384212|uncharacterized protein - GO:0003824//catalytic activity - gi|852755311|ref|XP_012873944.1|/2.86888e-146/PREDICTED: alpha/beta hydrolase domain-containing protein 17B [Dipodomys ordii] 232933 2010 3.216666667 3.276666667 0.026662474 Up 0.103999774 Ccdc61 coiled-coil domain containing 61 K16755|1|0.0|650|mmu:232933|coiled-coil domain-containing protein 61 - - - "gi|148691146|gb|EDL23093.1|/0/RIKEN cDNA C530028I08, isoform CRA_b [Mus musculus]" 80744 3407.03 2.746666667 2.803333333 0.029461463 Up 0.103999774 Cwc22 CWC22 spliceosome-associated protein K13100|1|0.0|1307|mmu:80744|pre-mRNA-splicing factor CWC22 - - - - 21888 4535.02 2.466666667 2.41 -0.033529624 Down 0.103999774 Tle4 transducin-like enhancer of split 4 K04497|1|0.0|1104|dre:30206|groucho GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle "GO:0003712//transcription cofactor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003712//transcription cofactor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003712//transcription cofactor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003712//transcription cofactor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0008134//transcription factor binding" GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter gi|965920364|ref|XP_014948655.1|/0/PREDICTED: transducin-like enhancer protein 4 isoform X6 [Ovis aries] 319822 3517 2.49 2.433333333 -0.033211779 Down 0.103999774 Smyd4 SET and MYND domain containing 4 K11426|1|2e-76|290|isc:IscW_ISCW000409|SET and MYND domain-containing protein - GO:0046914//transition metal ion binding - "gi|148680855|gb|EDL12802.1|/0/SET and MYND domain containing 4, isoform CRA_b, partial [Mus musculus]" 76561 2171 2.873333333 2.93 0.028175296 Up 0.103999774 Snx7 sorting nexin 7 K17921|1|0.0|774|ngi:103734645|sorting nexin-7/30 GO:0031982//vesicle GO:0005543//phospholipid binding GO:0045184//establishment of protein localization;GO:0044763 gi|297747317|ref|NP_083931.2|/0/sorting nexin-7 isoform 1 [Mus musculus] 56177 2204.16 2.853333333 2.796666667 -0.028939986 Down 0.103999774 Olfm1 olfactomedin 1 K04593|1|1e-54|217|mmu:99633|latrophilin 2 GO:0044421;GO:0008328//ionotropic glutamate receptor complex;GO:0044421;GO:0008328//ionotropic glutamate receptor complex;GO:0044421;GO:0008328//ionotropic glutamate receptor complex;GO:0044421;GO:0008328//ionotropic glutamate receptor complex GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0006461//protein complex assembly;GO:0048731//system development;GO:0006461//protein complex assembly;GO:0032502//developmental process;GO:0006461//protein complex assembly;GO:0048731//system development;GO:0006461//protein complex assembly;GO:0048731//system development gi|84370357|ref|NP_062371.2|/0/noelin isoform a precursor [Mus musculus] 75216 4826 2.993333333 3.05 0.027056298 Up 0.103999774 Cep128 centrosomal protein 128 K16460|1|0.0|1848|mmu:75216|centrosomal protein CEP128 GO:0005813//centrosome - - gi|160333189|ref|NP_861536.3|/0/centrosomal protein of 128 kDa [Mus musculus] 76804 4207 2.676666667 2.616666667 -0.032707334 Down 0.103999774 Kdm4c lysine (K)-specific demethylase 4C K06709|1|0.0|2119|mmu:76804|jumonji domain-containing protein 2 [EC:1.14.11.-] GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin "GO:0032452//histone demethylase activity;GO:0046914//transition metal ion binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0035258//steroid hormone receptor binding;GO:0032452//histone demethylase activity;GO:0046914//transition metal ion binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0035258//steroid hormone receptor binding" GO:0070076//histone lysine demethylation;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0070076//histone lysine demethylation;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter gi|50510631|dbj|BAD32301.1|/0/mKIAA0780 protein [Mus musculus] 94246 5984.16 2.786666667 2.846666667 0.030733128 Up 0.103999774 Arid4b AT rich interactive domain 4B (RBP1-like) K19195|1|0.0|1789|mmu:94246|AT-rich interactive domain-containing protein 4B GO:0005622//intracellular;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0040029//regulation of gene expression, epigenetic;GO:0018023//peptidyl-lysine trimethylation;GO:0006351//transcription, DNA-templated;GO:0040029//regulation of gene expression, epigenetic;GO:0018023//peptidyl-lysine trimethylation;GO:0006351//transcription, DNA-templated" gi|37694072|ref|NP_919238.1|/0/AT-rich interactive domain-containing protein 4B isoform 1 [Mus musculus] 269523 3315 165.1766667 164.02 -0.010138159 Down 0.103990372 Vcp valosin containing protein K13525|1|0.0|1454|pale:102890980|transitional endoplasmic reticulum ATPase GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0044427 GO:0043130//ubiquitin binding;GO:0019902//phosphatase binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0006915//apoptotic process;GO:0006301//postreplication repair;GO:0070841;GO:0016482//cytosolic transport;GO:0009154//purine ribonucleotide catabolic process;GO:0032446//protein modification by small protein conjugation;GO:0006984//ER-nucleus signaling pathway;GO:0006886//intracellular protein transport;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031331;GO:0051259//protein oligomerization;GO:0006487//protein N-linked glycosylation "gi|148670554|gb|EDL02501.1|/0/valosin containing protein, isoform CRA_b, partial [Mus musculus]" 110446 3373 157.7166667 158.8466667 0.010299691 Up 0.103971567 Acat1 acetyl-Coenzyme A acetyltransferase 1 K00626|1|0.0|731|mmu:110446|acetyl-CoA C-acetyltransferase [EC:2.3.1.9] GO:0019866//organelle inner membrane;GO:0042579//microbody;GO:0044429 GO:0043169//cation binding;GO:0003988//acetyl-CoA C-acyltransferase activity;GO:0042802//identical protein binding;GO:0048037//cofactor binding GO:0007417//central nervous system development;GO:0051259//protein oligomerization;GO:0009719;GO:0072019//proximal convoluted tubule development;GO:0006950//response to stress;GO:0010033//response to organic substance "gi|21450129|ref|NP_659033.1|/0/acetyl-CoA acetyltransferase, mitochondrial precursor [Mus musculus]" 20867 2173 79.71 80.52 0.014586444 Up 0.103576667 Stip1 stress-induced phosphoprotein 1 K09553|1|0.0|1027|mmu:20867|stress-induced-phosphoprotein 1 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle GO:0031072//heat shock protein binding - gi|14389431|ref|NP_058017.1|/0/stress-induced-phosphoprotein 1 [Mus musculus] 69875 2661 84 83.19333333 -0.013921405 Down 0.103576667 Ndufa11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 11 K03956|1|4e-78|295|mmu:69875|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11 GO:0031224//intrinsic component of membrane;GO:0005746//mitochondrial respiratory chain - GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy gi|226437665|ref|NP_081520.1|/3.09117e-77/NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 [Mus musculus] 19052 1930 122.92 122.12 -0.009420177 Down 0.10354846 Ppp2ca "protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform" K04382|1|0.0|653|ngi:103729809|serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle;GO:0008287//protein serine/threonine phosphatase complex;GO:0044444//cytoplasmic part;GO:0044427;GO:0016020//membrane GO:0004672//protein kinase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding;GO:0046983//protein dimerization activity "GO:0022403;GO:0009894;GO:0016055//Wnt signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006396//RNA processing;GO:0006665//sphingolipid metabolic process;GO:0016049//cell growth;GO:0006351//transcription, DNA-templated;GO:0001837//epithelial to mesenchymal transition;GO:0012502//induction of programmed cell death;GO:0043407//negative regulation of MAP kinase activity;GO:0042221//response to chemical;GO:0006260//DNA replication;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0007155//cell adhesion;GO:0051291//protein heterooligomerization;GO:0045860//positive regulation of protein kinase activity;GO:0042503//tyrosine phosphorylation of Stat3 protein" "gi|491668487|pdb|4I5L|C/0/Chain C, Structural Mechanism Of Trimeric Pp2a Holoenzyme Involving Pr70: Insight For Cdc6 Dephosphorylation" 66117 441 79.61333333 78.82 -0.014448319 Down 0.103529655 1110001J03Rik formation of mitochondrial complex V assembly factor 1 K13212|1|2e-41|169|hsa:100996928|RNA-binding protein Luc7-like 2 GO:0043231//intracellular membrane-bounded organelle - - gi|13384728|ref|NP_079639.1|/2.61909e-59/UPF0562 protein C7orf55 homolog [Mus musculus] 68460 1129 103.9366667 103.1633333 -0.010774402 Down 0.10351085 Dhrs7c dehydrogenase/reductase (SDR family) member 7C K11167|1|5e-165|582|mmu:68460|dehydrogenase/reductase SDR family member 7C [EC:1.1.-.-] - - - - 53379 2266.39 87.88333333 88.60666667 0.011825659 Up 0.103416827 Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 K13158|1|1e-102|376|pss:102456185|heterogeneous nuclear ribonucleoprotein A2/B1 GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen GO:0036002//pre-mRNA binding;GO:0003697//single-stranded DNA binding;GO:0036094//small molecule binding;GO:0036002//pre-mRNA binding;GO:0003697//single-stranded DNA binding;GO:0036094//small molecule binding;GO:0036002//pre-mRNA binding;GO:0003697//single-stranded DNA binding;GO:0036094//small molecule binding "GO:0050657;GO:0000398//mRNA splicing, via spliceosome;GO:0050657;GO:0000398//mRNA splicing, via spliceosome;GO:0050657;GO:0000398//mRNA splicing, via spliceosome" "gi|148666221|gb|EDK98637.1|/2.87687e-113/mCG119114, isoform CRA_a, partial [Mus musculus]" 75957 2339 0.17 0.15 -0.180572246 Down 0.103369815 Mir17hg Mir17 host gene (non-protein coding) - - - - "gi|148668220|gb|EDL00550.1|/1.20576e-29/mCG1042649, partial [Mus musculus]" 96935 2035 0.173333333 0.153333333 -0.176877762 Down 0.103369815 Susd4 sushi domain containing 4 K17495|1|1e-24|117|mdo:100022943|CUB and sushi domain-containing protein GO:0031224//intrinsic component of membrane - - "gi|148681153|gb|EDL13100.1|/0/sushi domain containing 4, isoform CRA_a, partial [Mus musculus]" 100039684 719 0.143333333 0.126666667 -0.178337241 Down 0.103369815 5031434O11Rik RIKEN cDNA 5031434O11 gene - - - - - 104601 2944 0.17 0.15 -0.180572246 Down 0.103369815 Mycbpap MYCBP associated protein - GO:0019898//extrinsic component of membrane;GO:0044424 - GO:0050954//sensory perception of mechanical stimulus;GO:0007267//cell-cell signaling;GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|168229259|ref|NP_733771.2|/0/MYCBP-associated protein [Mus musculus] 67289 837 0.196666667 0.173333333 -0.182203331 Down 0.103369815 3110021A11Rik RIKEN cDNA 3110021A11 gene - - - - gi|12851709|dbj|BAB29140.1|/2.79304e-51/unnamed protein product [Mus musculus] 75732 1668 0.15 0.17 0.180572246 Up 0.103369815 Iqcd IQ motif containing D K10397|1|3e-13|79.3|cin:100184728|kinesin family member 6/9;K20283|2|7e-07|58.2|aam:106489000|golgin subfamily A member 4;K20358|3|3e-06|56.2|lcm:102354675|golgin subfamily A member 2 - - - "gi|148687816|gb|EDL19763.1|/0/IQ motif containing D, isoform CRA_b, partial [Mus musculus]" 381337 909 0.173333333 0.153333333 -0.176877762 Down 0.103369815 Fam178b "family with sequence similarity 178, member B" - - - - gi|186659514|ref|NP_001119518.1|/0/protein FAM178B isoform A [Mus musculus] 78806 2380 0.146666667 0.166666667 0.184424571 Up 0.103369815 Stpg1 sperm tail PG rich repeat containing 1 - GO:0043231//intracellular membrane-bounded organelle - GO:0012501//programmed cell death gi|21313496|ref|NP_084465.1|/0/O(6)-methylguanine-induced apoptosis 2 [Mus musculus] 245841 787 5.756666667 5.663333333 -0.02358223 Down 0.103322803 Polr2h polymerase (RNA) II (DNA directed) polypeptide H "K03016|1|5e-85|307|nle:100582655|DNA-directed RNA polymerases I, II, and III subunit RPABC3" "GO:0016591//DNA-directed RNA polymerase II, holoenzyme" GO:0046914//transition metal ion binding;GO:0016301//kinase activity;GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity GO:0006383//transcription from RNA polymerase III promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006397//mRNA processing;GO:0044764;GO:0006289//nucleotide-excision repair;GO:0000377;GO:0006464//cellular protein modification process;GO:0006360//transcription from RNA polymerase I promoter "gi|332214985|ref|XP_003256616.1|/3.93008e-84/PREDICTED: DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1 [Nomascus leucogenys]" 56392 4075 7.083333333 6.993333333 -0.018448163 Down 0.103322803 Shoc2 soc-2 (suppressor of clear) homolog (C. elegans) K19613|1|0.0|912|mmu:56392|leucine-rich repeat protein SHOC2 GO:0008287//protein serine/threonine phosphatase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0008287//protein serine/threonine phosphatase complex;GO:0043231//intracellular membrane-bounded organelle GO:0019902//phosphatase binding;GO:0019208//phosphatase regulator activity;GO:0019902//phosphatase binding;GO:0019208//phosphatase regulator activity GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007265//Ras protein signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007265//Ras protein signal transduction gi|31543701|ref|NP_062632.2|/0/leucine-rich repeat protein SHOC-2 [Mus musculus] 78783 4752.06 7.876666667 7.963333333 0.015787224 Up 0.103322803 Brpf1 "bromodomain and PHD finger containing, 1" K11348|1|0.0|2090|mmu:78783|bromodomain and PHD finger-containing protein 1 GO:0070775;GO:0070775;GO:0070775;GO:0070775 GO:0043169//cation binding;GO:0043169//cation binding;GO:0043169//cation binding;GO:0043169//cation binding "GO:0006351//transcription, DNA-templated;GO:0016573//histone acetylation;GO:0006351//transcription, DNA-templated;GO:0016573//histone acetylation;GO:0006351//transcription, DNA-templated;GO:0016573//histone acetylation;GO:0006351//transcription, DNA-templated;GO:0016573//histone acetylation" gi|530788314|ref|NP_001269055.1|/0/peregrin isoform 1 [Mus musculus] 18514 6317.97 6.576666667 6.67 0.020330211 Up 0.103322803 Pbx1 pre B cell leukemia homeobox 1 K09355|1|0.0|598|ecb:100058426|pre-B-cell leukemia transcription factor 1 GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003677//DNA binding GO:0001501//skeletal system development;GO:0030097//hemopoiesis;GO:0008202//steroid metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0003006//developmental process involved in reproduction;GO:0008283//cell proliferation;GO:0035108//limb morphogenesis;GO:0001503//ossification;GO:0003002//regionalization;GO:0044092//negative regulation of molecular function;GO:0009790//embryo development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0035270//endocrine system development;GO:0000086//G2/M transition of mitotic cell cycle;GO:0030182//neuron differentiation;GO:0001501//skeletal system development;GO:0030097//hemopoiesis;GO:0008202//steroid metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0003006//developmental process involved in reproduction;GO:0008283//cell proliferation;GO:0035108//limb morphogenesis;GO:0001503//ossification;GO:0003002//regionalization;GO:0044092//negative regulation of molecular function;GO:0009790//embryo development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0035270//endocrine system development;GO:0000086//G2/M transition of mitotic cell cycle;GO:0030182//neuron differentiation;GO:0001501//skeletal system development;GO:0030097//hemopoiesis;GO:0008202//steroid metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0003006//developmental process involved in reproduction;GO:0008283//cell proliferation;GO:0035108//limb morphogenesis;GO:0001503//ossification;GO:0003002//regionalization;GO:0044092//negative regulation of molecular function;GO:0009790//embryo development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0035270//endocrine system development;GO:0000086//G2/M transition of mitotic cell cycle;GO:0030182//neuron differentiation;GO:0001501//skeletal system development;GO:0030097//hemopoiesis;GO:0008202//steroid metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0003006//developmental process involved in reproduction;GO:0008283//cell proliferation;GO:0035108//limb morphogenesis;GO:0001503//ossification;GO:0003002//regionalization;GO:0044092//negative regulation of molecular function;GO:0009790//embryo development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0035270//endocrine system development;GO:0000086//G2/M transition of mitotic cell cycle;GO:0030182//neuron differentiation gi|149755772|ref|XP_001493290.1|/0/PREDICTED: pre-B-cell leukemia transcription factor 1 isoform X1 [Equus caballus] 18554 3878.35 8.36 8.453333333 0.016017397 Up 0.103322803 Pcsk7 proprotein convertase subtilisin/kexin type 7 K08673|1|0.0|1532|mmu:18554|proprotein convertase subtilisin/kexin type 7 [EC:3.4.21.-] - - - "gi|148693717|gb|EDL25664.1|/0/proprotein convertase subtilisin/kexin type 7, isoform CRA_a, partial [Mus musculus]" 66420 1022 74.74333333 75.44 0.013384771 Up 0.103322803 Polr2e polymerase (RNA) II (DNA directed) polypeptide E "K03013|1|2e-116|421|ngi:103737342|DNA-directed RNA polymerases I, II, and III subunit RPABC1" "GO:0016591//DNA-directed RNA polymerase II, holoenzyme" GO:0016301//kinase activity;GO:0003676//nucleic acid binding;GO:0034062//RNA polymerase activity GO:0006383//transcription from RNA polymerase III promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006397//mRNA processing;GO:0006289//nucleotide-excision repair;GO:0000377;GO:0006464//cellular protein modification process "gi|124249077|ref|NP_079830.2|/1.75636e-115/DNA-directed RNA polymerases I, II, and III subunit RPABC1 [Mus musculus]" 13418 5336.31 6.813333333 6.906666667 0.019628807 Up 0.103322803 Dnajc1 DnaJ heat shock protein family (Hsp40) member C1 K09521|1|0.0|874|mmu:13418|DnaJ homolog subfamily C member 1 - - - - 16475 3503 5.05 4.963333333 -0.02497404 Down 0.103322803 Ajuba ajuba LIM protein K16682|1|0.0|933|mmu:16475|LIM domain-containing protein GO:0031252//cell leading edge;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0005924//cell-substrate adherens junction GO:0003712//transcription cofactor activity;GO:0046914//transition metal ion binding;GO:0003779//actin binding "GO:0006461//protein complex assembly;GO:0043405//regulation of MAP kinase activity;GO:0030031//cell projection assembly;GO:0016337//single organismal cell-cell adhesion;GO:0008104//protein localization;GO:0044319//wound healing, spreading of cells;GO:0006650//glycerophospholipid metabolic process;GO:0035195//gene silencing by miRNA;GO:0009968//negative regulation of signal transduction;GO:0009891;GO:0006366//transcription from RNA polymerase II promoter;GO:0080135//regulation of cellular response to stress;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007044//cell-substrate junction assembly" gi|31981662|ref|NP_034720.2|/0/LIM domain-containing protein ajuba [Mus musculus] 14390 5004 6.816666667 6.73 -0.018459932 Down 0.103322803 Gabpa "GA repeat binding protein, alpha" "K09441|1|0.0|874|mmu:14390|GA-binding protein transcription factor, alpha" GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle "GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0046983//protein dimerization activity" GO:0006366//transcription from RNA polymerase II promoter;GO:0030219//megakaryocyte differentiation;GO:0043009//chordate embryonic development gi|34328119|ref|NP_032091.2|/0/GA-binding protein alpha chain [Mus musculus] 30932 1665 5.866666667 5.773333333 -0.023136499 Down 0.103322803 Zfp330 zinc finger protein 330 - GO:0044427;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding - gi|21704208|ref|NP_663575.1|/1.79988e-167/zinc finger protein 330 [Mus musculus] 76742 5586.77 5.246666667 5.16 -0.024030069 Down 0.103322803 Snx27 sorting nexin family member 27 K17936|1|0.0|1023|mmu:76742|sorting nexin-27 GO:0005768//endosome;GO:0031981//nuclear lumen;GO:0005768//endosome;GO:0031981//nuclear lumen GO:0005543//phospholipid binding;GO:0005543//phospholipid binding GO:0007041//lysosomal transport;GO:0048731//system development;GO:0045184//establishment of protein localization;GO:0042221//response to chemical;GO:0007154//cell communication;GO:0007041//lysosomal transport;GO:0048731//system development;GO:0045184//establishment of protein localization;GO:0042221//response to chemical;GO:0007154//cell communication gi|126722910|ref|NP_083997.1|/0/sorting nexin-27 isoform 2 [Mus musculus] 27280 1483 7.036666667 7.13 0.019009904 Up 0.103322803 Phlda3 "pleckstrin homology like domain, family A, member 3" - GO:0043227//membrane-bounded organelle;GO:0044424;GO:0016020//membrane GO:1901981//phosphatidylinositol phosphate binding;GO:0043168//anion binding GO:0012502//induction of programmed cell death;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0032502//developmental process gi|966922758|ref|XP_014975878.1|/7.37049e-69/PREDICTED: pleckstrin homology-like domain family A member 3 [Macaca mulatta] 16151 6814.06 5.146666667 5.06 -0.024500962 Down 0.103322803 Ikbkg inhibitor of kappaB kinase gamma K07210|1|0.0|669|mmu:16151|inhibitor of nuclear factor kappa-B kinase subunit gamma GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0046983//protein dimerization activity;GO:0043169//cation binding" GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032147//activation of protein kinase activity;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002260//lymphocyte homeostasis;GO:0033554//cellular response to stress;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032147//activation of protein kinase activity;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002260//lymphocyte homeostasis;GO:0033554//cellular response to stress;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032147//activation of protein kinase activity;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002260//lymphocyte homeostasis;GO:0033554//cellular response to stress;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032147//activation of protein kinase activity;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002260//lymphocyte homeostasis;GO:0033554//cellular response to stress;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032147//activation of protein kinase activity;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002260//lymphocyte homeostasis;GO:0033554//cellular response to stress;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032147//activation of protein kinase activity;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002260//lymphocyte homeostasis;GO:0033554//cellular response to stress;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032147//activation of protein kinase activity;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002260//lymphocyte homeostasis;GO:0033554//cellular response to stress gi|209862941|ref|NP_001129539.1|/0/NF-kappa-B essential modulator isoform 3 [Mus musculus] 66884 2407 5.373333333 5.283333333 -0.024368904 Down 0.103322803 Appbp2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 K19360|1|1e-12|78.2|cmk:103180824|nephrocystin-3 GO:0012506//vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0015631//tubulin binding;GO:0003774//motor activity GO:0015031//protein transport gi|148683813|gb|EDL15760.1|/0/amyloid beta precursor protein (cytoplasmic tail) binding protein 2 [Mus musculus] 11977 8196.06 1.22 1.263333333 0.0503542 Up 0.103294596 Atp7a "ATPase, Cu++ transporting, alpha polypeptide" K17686|1|0.0|2763|mmu:11977|Cu+-exporting ATPase [EC:3.6.3.54] GO:0031224//intrinsic component of membrane;GO:0005903//brush border;GO:0044459;GO:0005798//Golgi-associated vesicle;GO:0044297//cell body;GO:0005768//endosome;GO:0031224//intrinsic component of membrane;GO:0005903//brush border;GO:0044459;GO:0005798//Golgi-associated vesicle;GO:0044297//cell body;GO:0005768//endosome GO:0043682//copper-transporting ATPase activity;GO:0016531//copper chaperone activity;GO:0032550;GO:0005515//protein binding;GO:0043682//copper-transporting ATPase activity;GO:0016531//copper chaperone activity;GO:0032550;GO:0005515//protein binding GO:0010467//gene expression;GO:0009636//response to toxic substance;GO:0021859//pyramidal neuron differentiation;GO:0002294;GO:0035434//copper ion transmembrane transport;GO:0001501//skeletal system development;GO:0042415//norepinephrine metabolic process;GO:0030003//cellular cation homeostasis;GO:0043009//chordate embryonic development;GO:0043085//positive regulation of catalytic activity;GO:0009072//aromatic amino acid family metabolic process;GO:0016358//dendrite development;GO:0085029//extracellular matrix assembly;GO:0001942//hair follicle development;GO:0006586;GO:0007589//body fluid secretion;GO:0009154//purine ribonucleotide catabolic process;GO:0009101//glycoprotein biosynthetic process;GO:0048771//tissue remodeling;GO:0044708//single-organism behavior;GO:0006801//superoxide metabolic process;GO:0018193//peptidyl-amino acid modification;GO:0021533//cell differentiation in hindbrain;GO:0006119//oxidative phosphorylation;GO:0021953//central nervous system neuron differentiation;GO:0008637//apoptotic mitochondrial changes;GO:0035108//limb morphogenesis;GO:0043086//negative regulation of catalytic activity;GO:0010039//response to iron ion;GO:0043066//negative regulation of apoptotic process;GO:0030324//lung development;GO:0001944//vasculature development;GO:0010467//gene expression;GO:0009636//response to toxic substance;GO:0021859//pyramidal neuron differentiation;GO:0002294;GO:0035434//copper ion transmembrane transport;GO:0001501//skeletal system development;GO:0042415//norepinephrine metabolic process;GO:0030003//cellular cation homeostasis;GO:0043009//chordate embryonic development;GO:0043085//positive regulation of catalytic activity;GO:0009072//aromatic amino acid family metabolic process;GO:0016358//dendrite development;GO:0085029//extracellular matrix assembly;GO:0001942//hair follicle development;GO:0006586;GO:0007589//body fluid secretion;GO:0009154//purine ribonucleotide catabolic process;GO:0009101//glycoprotein biosynthetic process;GO:0048771//tissue remodeling;GO:0044708//single-organism behavior;GO:0006801//superoxide metabolic process;GO:0018193//peptidyl-amino acid modification;GO:0021533//cell differentiation in hindbrain;GO:0006119//oxidative phosphorylation;GO:0021953//central nervous system neuron differentiation;GO:0008637//apoptotic mitochondrial changes;GO:0035108//limb morphogenesis;GO:0043086//negative regulation of catalytic activity;GO:0010039//response to iron ion;GO:0043066//negative regulation of apoptotic process;GO:0030324//lung development;GO:0001944//vasculature development "gi|148682115|gb|EDL14062.1|/0/ATPase, Cu++ transporting, alpha polypeptide, isoform CRA_b, partial [Mus musculus]" 18600 4758 0.95 0.986666667 0.054635257 Up 0.103294596 Padi2 "peptidyl arginine deiminase, type II" K01481|1|0.0|1373|mmu:18600|protein-arginine deiminase [EC:3.5.3.15] GO:0044424 "GO:0046872//metal ion binding;GO:0016813//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines" GO:0018195//peptidyl-arginine modification gi|171906557|ref|NP_032838.2|/0/protein-arginine deiminase type-2 [Mus musculus] 93737 3143 1.356666667 1.4 0.045360533 Up 0.103294596 Pard6g par-6 family cell polarity regulator gamma K06093|1|0.0|703|mmu:93737|partitioning defective protein 6 GO:0016020//membrane;GO:0032991//macromolecular complex;GO:0043296//apical junction complex - GO:0044763 gi|238550190|ref|NP_444347.3|/0/partitioning defective 6 homolog gamma [Mus musculus] 71163 5329 1.143333333 1.183333333 0.049610448 Up 0.103294596 Zfp626 zinc finger protein 626 K09228|1|0.0|1456|mmu:71163|KRAB domain-containing zinc finger protein - - - gi|825706152|ref|NP_081979.1|/0/zinc finger protein 626 [Mus musculus] 51869 8502 1 0.963333333 -0.053893008 Down 0.103294596 Rif1 replication timing regulatory factor 1 K11138|1|0.0|4351|mmu:51869|telomere-associated protein RIF1 GO:0045120//pronucleus;GO:0043232 GO:0005488//binding GO:0032502//developmental process;GO:0033554//cellular response to stress gi|146231944|ref|NP_780447.4|/0/telomere-associated protein RIF1 [Mus musculus] 12489 2568.01 1.236666667 1.28 0.049687124 Up 0.103294596 Cd33 CD33 antigen K06473|1|2e-144|515|mmu:12489|CD33 antigen;K06549|4|1e-75|287|ngi:103743781|sialic acid binding Ig-like lectin 5/14 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane - GO:0022610;GO:0022610 gi|161484603|ref|NP_001104528.1|/0/myeloid cell surface antigen CD33 isoform 1 precursor [Mus musculus] 71226 1061 1.096666667 1.136666667 0.051684155 Up 0.103294596 4933433G19Rik RIKEN cDNA 4933433G19 gene - - - - "gi|148678381|gb|EDL10328.1|/1.10698e-59/mCG146107, partial [Mus musculus]" 12724 3670 1.25 1.29 0.045442971 Up 0.103294596 Clcn2 "chloride channel, voltage-sensitive 2" K05011|1|0.0|1614|mmu:12724|chloride channel 2 GO:0043005//neuron projection;GO:0005856//cytoskeleton;GO:0043025//neuronal cell body;GO:0034702//ion channel complex GO:0005254//chloride channel activity GO:0030323//respiratory tube development;GO:0043010//camera-type eye development;GO:0015698//inorganic anion transport;GO:0007431//salivary gland development;GO:0034220//ion transmembrane transport "gi|148665174|gb|EDK97590.1|/0/chloride channel 2, partial [Mus musculus]" 108011 6524 1.296666667 1.256666667 -0.045205632 Down 0.103294596 Ap4e1 "adaptor-related protein complex AP-4, epsilon 1" K12400|1|0.0|2093|mmu:108011|AP-4 complex subunit epsilon-1 - - - - 434310 2395 1.02 1.056666667 0.050951187 Up 0.103294596 AY512931 cDNA sequence AY512931 - - - - - 100049077 723 1.066666667 1.106666667 0.053111336 Up 0.103294596 LOC100049077 uncharacterized LOC100049077 - GO:0043234//protein complex GO:0017111//nucleoside-triphosphatase activity;GO:0043566//structure-specific DNA binding GO:0009154//purine ribonucleotide catabolic process;GO:0031647//regulation of protein stability gi|148693287|gb|EDL25234.1|/1.74478e-74/mCG147882 [Mus musculus] 414115 1734 1.23 1.19 -0.047696742 Down 0.103294596 D330050I16Rik RIKEN cDNA D330050I16 gene - - - - "gi|148701171|gb|EDL33118.1|/3.84991e-19/mCG140513, partial [Mus musculus]" 216976 3245 0.15 0.133333333 -0.169925001 Down 0.103172365 BC030499 cDNA sequence BC030499 K17529|1|0.0|748|mmu:216976|uncharacterized serine/threonine-protein kinase SgK494 [EC:2.7.11.1] - - - - 72080 3305 0.163333333 0.183333333 0.166649869 Up 0.103172365 Sapcd2 suppressor APC domain containing 2 - GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - - gi|124487325|ref|NP_001074554.1|/0/suppressor APC domain-containing protein 2 isoform a [Mus musculus] 19726 9146 0.136666667 0.153333333 0.166009951 Up 0.103172365 Rfx3 "regulatory factor X, 3 (influences HLA class II expression)" K09173|1|0.0|1307|mmu:19726|regulatory factor X 1/2/3 GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0000785//chromatin;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0010720//positive regulation of cell development;GO:0009855//determination of bilateral symmetry;GO:0021700//developmental maturation;GO:0030073//insulin secretion;GO:0001539//cilium or flagellum-dependent cell motility;GO:0003323//type B pancreatic cell development;GO:0010927;GO:0003351//epithelial cilium movement;GO:0006366//transcription from RNA polymerase II promoter;GO:0010720//positive regulation of cell development;GO:0009855//determination of bilateral symmetry;GO:0021700//developmental maturation;GO:0030073//insulin secretion;GO:0001539//cilium or flagellum-dependent cell motility;GO:0003323//type B pancreatic cell development;GO:0010927;GO:0003351//epithelial cilium movement gi|829738084|ref|XP_012593007.1|/0/PREDICTED: transcription factor RFX3 isoform X5 [Microcebus murinus] 20681 2999 0.163333333 0.183333333 0.166649869 Up 0.103172365 Sox8 SRY (sex determining region Y)-box 8 K09270|1|0.0|679|mmu:20681|transcription factor SOX7/8/10/18 (SOX group E/F) GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0005515//protein binding;GO:0003677//DNA binding GO:0045665//negative regulation of neuron differentiation;GO:0021700//developmental maturation;GO:0001763//morphogenesis of a branching structure;GO:0045445//myoblast differentiation;GO:0006915//apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0008406//gonad development;GO:0043009//chordate embryonic development;GO:0072079//nephron tubule formation;GO:0048232//male gamete generation;GO:0051094//positive regulation of developmental process;GO:0001667//ameboidal-type cell migration;GO:0001503//ossification;GO:0060219//camera-type eye photoreceptor cell differentiation;GO:0007417//central nervous system development;GO:0065008//regulation of biological quality;GO:0006366//transcription from RNA polymerase II promoter;GO:0048483//autonomic nervous system development;GO:0014013//regulation of gliogenesis;GO:0031128//developmental induction;GO:0021781//glial cell fate commitment;GO:0007519//skeletal muscle tissue development gi|33563276|ref|NP_035577.1|/0/transcription factor SOX-8 [Mus musculus] 13395 1328 0.15 0.133333333 -0.169925001 Down 0.103172365 Dlx5 distal-less homeobox 5 K18489|1|1e-148|297|mmu:13395|homeobox protein DLX5 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0001071//nucleic acid binding transcription factor activity;GO:0019904//protein domain specific binding;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0019904//protein domain specific binding;GO:0000975//regulatory region DNA binding GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0035108//limb morphogenesis;GO:0043584//nose development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0008284//positive regulation of cell proliferation;GO:0036075;GO:0006935//chemotaxis;GO:0042471//ear morphogenesis;GO:0030177//positive regulation of Wnt signaling pathway;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0035108//limb morphogenesis;GO:0043584//nose development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0008284//positive regulation of cell proliferation;GO:0036075;GO:0006935//chemotaxis;GO:0042471//ear morphogenesis;GO:0030177//positive regulation of Wnt signaling pathway gi|38524596|ref|NP_034186.2|/1.17539e-147/homeobox protein DLX-5 isoform 1 [Mus musculus] 102632192 2345 0.19 0.213333333 0.167109986 Up 0.103172365 Gm30332 "predicted gene, 30332" - - - - - 83945 2581.76 87.80666667 88.45666667 0.010640398 Up 0.10315356 Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 K09504|1|0.0|904|mmu:83945|DnaJ homolog subfamily A member 3 - - - - 19241 670 185.1766667 185.8266667 0.005055225 Up 0.10315356 Tmsb4x "thymosin, beta 4, X chromosome" "K05764|1|7e-22|105|cjc:100399195|thymosin, beta 4" GO:0031091//platelet alpha granule;GO:0043232 GO:0008092//cytoskeletal protein binding "GO:0006351//transcription, DNA-templated;GO:0007599//hemostasis;GO:0014909//smooth muscle cell migration;GO:0006887//exocytosis;GO:0001775//cell activation;GO:0030837//negative regulation of actin filament polymerization;GO:0051145//smooth muscle cell differentiation" "gi|207318|gb|AAA42246.1|/8.51532e-22/thymosin beta-4 precursor, partial [Rattus norvegicus]" 100503353 3382 0.556666667 0.59 0.083901258 Up 0.103134755 Gm14440 predicted gene 14440 K09228|1|2e-168|550|gja:107106186|KRAB domain-containing zinc finger protein - - - - 330554 3475 0.466666667 0.44 -0.084888898 Down 0.103134755 Fan1 FANCD2/FANCI-associated nuclease 1 K15363|1|0.0|2039|mmu:330554|fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1] - - - gi|257467664|ref|NP_808561.2|/0/fanconi-associated nuclease 1 [Mus musculus] 102466779 115 0.65 0.616666667 -0.075948853 Down 0.103134755 Mir6981 microRNA 6981 - - - - - 241113 2835 0.643333333 0.61 -0.076757199 Down 0.103134755 Prkag3 "protein kinase, AMP-activated, gamma 3 non-catatlytic subunit" "K07200|1|0.0|944|mmu:241113|5'-AMP-activated protein kinase, regulatory gamma subunit" GO:0043234//protein complex GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0019900//kinase binding GO:0006631//fatty acid metabolic process;GO:0008645//hexose transport;GO:0005977//glycogen metabolic process "gi|148667932|gb|EDL00349.1|/0/protein kinase, AMP-activated, gamma 3 non-catatlytic subunit, isoform CRA_a, partial [Mus musculus]" 75665 1853 0.583333333 0.616666667 0.080170349 Up 0.103134755 Ccdc64 coiled-coil domain containing 64 K16756|1|0.0|834|mmu:75665|coiled-coil domain-containing protein 64 GO:0005815//microtubule organizing center GO:0017016//Ras GTPase binding;GO:0008092//cytoskeletal protein binding GO:0048731//system development;GO:0016482//cytosolic transport;GO:0030030//cell projection organization gi|124248514|ref|NP_001074277.1|/0/bicaudal D-related protein 1 [Mus musculus] 99526 4014 0.496666667 0.47 -0.079617168 Down 0.103134755 Usp53 ubiquitin specific peptidase 53 "K14206|1|1e-30|138|dpe:Dper_GL26826|solute carrier family 15 (oligopeptide transporter), member 1" - GO:0016790//thiolester hydrolase activity GO:0019941//modification-dependent protein catabolic process gi|33469031|ref|NP_598618.1|/0/inactive ubiquitin carboxyl-terminal hydrolase 53 [Mus musculus] 75379 880 0.466666667 0.44 -0.084888898 Down 0.103134755 4930599N23Rik RIKEN cDNA 4930599N23 gene K11445|1|1e-22|109|mmu:338523|lysine-specific demethylase 7A [EC:1.14.11.-] - - - - 16202 1762.51 70.09333333 70.73333333 0.013113016 Up 0.103097145 Ilk integrin linked kinase K06272|1|0.0|941|rno:170922|integrin-linked kinase [EC:2.7.11.1] GO:0033267;GO:0032991//macromolecular complex;GO:0031252//cell leading edge;GO:0032432//actin filament bundle;GO:0030425//dendrite;GO:0030016//myofibril;GO:0044297//cell body;GO:0016020//membrane;GO:0005924//cell-substrate adherens junction;GO:0033267;GO:0032991//macromolecular complex;GO:0031252//cell leading edge;GO:0032432//actin filament bundle;GO:0030425//dendrite;GO:0030016//myofibril;GO:0044297//cell body;GO:0016020//membrane;GO:0005924//cell-substrate adherens junction GO:0004672//protein kinase activity;GO:0060089;GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0004672//protein kinase activity;GO:0060089;GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0032550;GO:0019904//protein domain specific binding GO:0001952//regulation of cell-matrix adhesion;GO:0030177//positive regulation of Wnt signaling pathway;GO:0045445//myoblast differentiation;GO:0043405//regulation of MAP kinase activity;GO:0048754//branching morphogenesis of an epithelial tube;GO:0014044//Schwann cell development;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0022402//cell cycle process;GO:0010927;GO:0031346//positive regulation of cell projection organization;GO:0001933//negative regulation of protein phosphorylation;GO:0007409//axonogenesis;GO:0030509//BMP signaling pathway;GO:0001649//osteoblast differentiation;GO:0007568//aging;GO:0030307//positive regulation of cell growth;GO:0030198//extracellular matrix organization;GO:0008285//negative regulation of cell proliferation;GO:0010659//cardiac muscle cell apoptotic process;GO:0051259//protein oligomerization;GO:0030036//actin cytoskeleton organization;GO:0014909//smooth muscle cell migration;GO:0043066//negative regulation of apoptotic process;GO:0001952//regulation of cell-matrix adhesion;GO:0030177//positive regulation of Wnt signaling pathway;GO:0045445//myoblast differentiation;GO:0043405//regulation of MAP kinase activity;GO:0048754//branching morphogenesis of an epithelial tube;GO:0014044//Schwann cell development;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0022402//cell cycle process;GO:0010927;GO:0031346//positive regulation of cell projection organization;GO:0001933//negative regulation of protein phosphorylation;GO:0007409//axonogenesis;GO:0030509//BMP signaling pathway;GO:0001649//osteoblast differentiation;GO:0007568//aging;GO:0030307//positive regulation of cell growth;GO:0030198//extracellular matrix organization;GO:0008285//negative regulation of cell proliferation;GO:0010659//cardiac muscle cell apoptotic process;GO:0051259//protein oligomerization;GO:0030036//actin cytoskeleton organization;GO:0014909//smooth muscle cell migration;GO:0043066//negative regulation of apoptotic process gi|831211528|ref|XP_012658219.1|/0/PREDICTED: integrin-linked protein kinase isoform X1 [Otolemur garnettii] 66077 1209 60.37 61 0.014977442 Up 0.103078341 Aurkaip1 aurora kinase A interacting protein 1 K16830|1|2e-112|408|mmu:66077|aurora kinase A-interacting protein GO:0031981//nuclear lumen "GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0006508//proteolysis gi|13384706|ref|NP_079614.1|/1.52687e-111/aurora kinase A-interacting protein [Mus musculus] 15081 1993 62.65 62.08333333 -0.01310849 Down 0.102909098 H3f3b "H3 histone, family 3B" K11253|1|8e-77|290|lve:103081391|histone H3 - - - - 18081 1132 86.43333333 85.86 -0.009601628 Down 0.102909098 Ninj1 ninjurin 1 - GO:0016020//membrane - - "gi|148709118|gb|EDL41064.1|/1.61099e-59/ninjurin 1, isoform CRA_c, partial [Mus musculus]" 69662 1252 134.3066667 133.7733333 -0.005740364 Down 0.102796269 2310061I04Rik RIKEN cDNA 2310061I04 gene - GO:0043231//intracellular membrane-bounded organelle - - gi|158262037|ref|NP_001028802.1|/8.44194e-129/uncharacterized protein C6orf136 homolog [Mus musculus] 21401 1247 119.8066667 119.2733333 -0.006436662 Down 0.102796269 Tcea3 "transcription elongation factor A (SII), 3" K03145|1|1e-91|339|mdo:100024162|transcription elongation factor S-II GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0008135//translation factor activity, RNA binding" "GO:0006412//translation;GO:0006354//DNA-templated transcription, elongation;GO:0006366//transcription from RNA polymerase II promoter" gi|32189438|ref|NP_035672.1|/1.25031e-164/transcription elongation factor A protein 3 [Mus musculus] 18148 1407.2 64.00333333 63.47666667 -0.011920673 Down 0.102796269 Npm1 nucleophosmin 1 K11276|1|6e-134|479|rno:25498|nucleophosmin 1 GO:0016604//nuclear body;GO:0000922//spindle pole;GO:0044452//nucleolar part;GO:0005815//microtubule organizing center;GO:0044391//ribosomal subunit;GO:0016604//nuclear body;GO:0000922//spindle pole;GO:0044452//nucleolar part;GO:0005815//microtubule organizing center;GO:0044391//ribosomal subunit;GO:0016604//nuclear body;GO:0000922//spindle pole;GO:0044452//nucleolar part;GO:0005815//microtubule organizing center;GO:0044391//ribosomal subunit GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0003723//RNA binding;GO:0043021//ribonucleoprotein complex binding;GO:0046983//protein dimerization activity;GO:0043168//anion binding;GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0003723//RNA binding;GO:0043021//ribonucleoprotein complex binding;GO:0046983//protein dimerization activity;GO:0043168//anion binding;GO:0003712//transcription cofactor activity;GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0003723//RNA binding;GO:0043021//ribonucleoprotein complex binding;GO:0046983//protein dimerization activity;GO:0043168//anion binding "GO:0019725//cellular homeostasis;GO:0046605//regulation of centrosome cycle;GO:0000054//ribosomal subunit export from nucleus;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0060700//regulation of ribonuclease activity;GO:0010638//positive regulation of organelle organization;GO:0010639;GO:0032070;GO:0001934//positive regulation of protein phosphorylation;GO:0040007//growth;GO:0007568//aging;GO:0042981//regulation of apoptotic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006260//DNA replication;GO:0009891;GO:0008283//cell proliferation;GO:0007099//centriole replication;GO:0000398//mRNA splicing, via spliceosome;GO:0051259//protein oligomerization;GO:0033036;GO:0031647//regulation of protein stability;GO:0034728//nucleosome organization;GO:0019725//cellular homeostasis;GO:0046605//regulation of centrosome cycle;GO:0000054//ribosomal subunit export from nucleus;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0060700//regulation of ribonuclease activity;GO:0010638//positive regulation of organelle organization;GO:0010639;GO:0032070;GO:0001934//positive regulation of protein phosphorylation;GO:0040007//growth;GO:0007568//aging;GO:0042981//regulation of apoptotic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006260//DNA replication;GO:0009891;GO:0008283//cell proliferation;GO:0007099//centriole replication;GO:0000398//mRNA splicing, via spliceosome;GO:0051259//protein oligomerization;GO:0033036;GO:0031647//regulation of protein stability;GO:0034728//nucleosome organization;GO:0019725//cellular homeostasis;GO:0046605//regulation of centrosome cycle;GO:0000054//ribosomal subunit export from nucleus;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0060700//regulation of ribonuclease activity;GO:0010638//positive regulation of organelle organization;GO:0010639;GO:0032070;GO:0001934//positive regulation of protein phosphorylation;GO:0040007//growth;GO:0007568//aging;GO:0042981//regulation of apoptotic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006260//DNA replication;GO:0009891;GO:0008283//cell proliferation;GO:0007099//centriole replication;GO:0000398//mRNA splicing, via spliceosome;GO:0051259//protein oligomerization;GO:0033036;GO:0031647//regulation of protein stability;GO:0034728//nucleosome organization" gi|672066794|ref|XP_008765768.1|/2.71614e-137/PREDICTED: nucleophosmin isoform X1 [Rattus norvegicus] 69010 430 144.58 145.1 0.005179524 Up 0.102730452 Anapc13 anaphase promoting complex subunit 13 K12456|1|9e-40|163|phd:102337957|anaphase-promoting complex subunit 13 GO:0000152//nuclear ubiquitin ligase complex - GO:0000209//protein polyubiquitination;GO:0000087//mitotic M phase gi|926684112|ref|XP_005675606.2|/8.84696e-39/PREDICTED: anaphase-promoting complex subunit 13 isoform X1 [Capra hircus] 56407 3219 57.71666667 57.2 -0.012972835 Down 0.102730452 Trpc4ap "transient receptor potential cation channel, subfamily C, member 4 associated protein" K11796|1|0.0|1405|mmu:56407|Trpc4-associated protein GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0080008//Cul4-RING E3 ubiquitin ligase complex GO:0019899//enzyme binding;GO:0019899//enzyme binding GO:0019941//modification-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation;GO:0019941//modification-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation gi|60359890|dbj|BAD90164.1|/0/mFLJ00177 protein [Mus musculus] 56248 2776 59.35 59.87333333 0.012665562 Up 0.102730452 Ak3 adenylate kinase 3 K00944|1|1e-126|456|mmu:56248|nucleoside-triphosphate--adenylate kinase [EC:2.7.4.10] GO:0005740//mitochondrial envelope "GO:0032550;GO:0005515//protein binding;GO:0019205//nucleobase-containing compound kinase activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0009151;GO:0006754//ATP biosynthetic process;GO:0051259//protein oligomerization;GO:0009208;GO:0022037//metencephalon development;GO:0021988//olfactory lobe development;GO:0006950//response to stress "gi|23956104|ref|NP_067274.1|/1.09739e-125/GTP:AMP phosphotransferase AK3, mitochondrial [Mus musculus]" 14387 3536.72 79.42666667 79.94333333 0.009354271 Up 0.102730452 Gaa "glucosidase, alpha, acid" K12316|1|0.0|1883|mmu:14387|lysosomal alpha-glucosidase [EC:3.2.1.20] - - - - 11640 3759.93 56.51 55.99666667 -0.013165239 Down 0.10272105 Akap1 A kinase (PRKA) anchor protein 1 "K16518|1|0.0|1571|mmu:11640|A-kinase anchor protein 1, mitochondrial" GO:0097060//synaptic membrane;GO:0005743//mitochondrial inner membrane;GO:0031224//intrinsic component of membrane "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0051018//protein kinase A binding;GO:0019903//protein phosphatase binding;GO:0015631//tubulin binding;GO:0019900//kinase binding" GO:0042992//negative regulation of transcription factor import into nucleus;GO:0032868//response to insulin;GO:0003300//cardiac muscle hypertrophy;GO:0006470//protein dephosphorylation "gi|110347477|ref|NP_001036006.1|/0/A-kinase anchor protein 1, mitochondrial [Mus musculus]" 14712 2984 106.52 106.02 -0.006787888 Down 0.102636429 Gnpat glyceronephosphate O-acyltransferase K00649|1|0.0|1268|mmu:14712|glyceronephosphate O-acyltransferase [EC:2.3.1.42] GO:0044439 GO:0005515//protein binding;GO:0016413//O-acetyltransferase activity;GO:0047617//acyl-CoA hydrolase activity GO:0009653//anatomical structure morphogenesis;GO:0007043//cell-cell junction assembly;GO:0046485//ether lipid metabolic process;GO:0008366//axon ensheathment;GO:0006950//response to stress;GO:0033993//response to lipid;GO:0006644//phospholipid metabolic process;GO:0031667//response to nutrient levels gi|160298207|ref|NP_034452.3|/0/dihydroxyacetone phosphate acyltransferase [Mus musculus] 246703 905 62.25333333 62.75333333 0.011541006 Up 0.102636429 Apoa1bp apolipoprotein A-I binding protein K17759|1|2e-153|543|mmu:246703|NAD(P)H-hydrate epimerase [EC:5.1.99.6] GO:0044421;GO:0043231//intracellular membrane-bounded organelle GO:0042802//identical protein binding;GO:0016854//racemase and epimerase activity;GO:0043169//cation binding GO:0051260//protein homooligomerization gi|21553309|ref|NP_659146.1|/1.45568e-152/NAD(P)H-hydrate epimerase precursor [Mus musculus] 68581 3526 47.70333333 47.21333333 -0.014895737 Down 0.102580014 Tmed10 transmembrane emp24-like trafficking protein 10 (yeast) K20352|1|3e-107|392|mmu:68581|p24 family protein delta-1 GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0030133//transport vesicle;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0030667//secretory granule membrane;GO:0048770;GO:0005798//Golgi-associated vesicle GO:0005515//protein binding GO:0006903//vesicle targeting;GO:0010243//response to organonitrogen compound;GO:0006887//exocytosis;GO:0048194//Golgi vesicle budding;GO:0006461//protein complex assembly;GO:0044767//single-organism developmental process;GO:0042987//amyloid precursor protein catabolic process;GO:0015031//protein transport gi|625199217|ref|XP_007641584.1|/2.55035e-114/PREDICTED: transmembrane emp24 domain-containing protein 10 isoform X1 [Cricetulus griseus] 209039 4707 103.3733333 102.89 -0.006761297 Down 0.102542405 Tns2 tensin 2 K18080|1|0.0|2856|mmu:209039|tensin - - - - 170736 3705 70.12666667 69.65333333 -0.009770758 Down 0.102495393 Parvb "parvin, beta" K06275|1|0.0|655|mmu:170736|parvin - - - - 69556 1408 60.96 61.42666667 0.011002194 Up 0.102495393 Bod1 biorientation of chromosomes in cell division 1 - "GO:0000775//chromosome, centromeric region;GO:0015630//microtubule cytoskeleton" - GO:0000087//mitotic M phase gi|404351667|ref|NP_001013876.2|/1.627e-62/biorientation of chromosomes in cell division protein 1 [Rattus norvegicus] 19035 979 57.13333333 57.59666667 0.011652616 Up 0.102420174 Ppib peptidylprolyl isomerase B K03768|1|4e-111|403|mmu:19035|peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] GO:0044432;GO:0048770 GO:0033218//amide binding;GO:0003824//catalytic activity GO:0046907//intracellular transport;GO:0044267//cellular protein metabolic process gi|71774133|ref|NP_035279.2|/3.52185e-110/peptidyl-prolyl cis-trans isomerase B precursor [Mus musculus] 26417 1772 61.48666667 61.94 0.010597786 Up 0.102373162 Mapk3 mitogen-activated protein kinase 3 K04371|1|0.0|713|mmu:26417|mitogen-activated protein kinase 1/3 [EC:2.7.11.24] GO:0005856//cytoskeleton;GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0044459;GO:0042995//cell projection;GO:0005768//endosome;GO:0005924//cell-substrate adherens junction GO:0045309//protein phosphorylated amino acid binding;GO:0032550;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0019899//enzyme binding "GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007010//cytoskeleton organization;GO:0001501//skeletal system development;GO:0009612//response to mechanical stimulus;GO:0001676//long-chain fatty acid metabolic process;GO:0032091//negative regulation of protein binding;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0043331//response to dsRNA;GO:0043410//positive regulation of MAPK cascade;GO:0009653//anatomical structure morphogenesis;GO:0019221//cytokine-mediated signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:0007600//sensory perception;GO:0001934//positive regulation of protein phosphorylation;GO:0002237//response to molecule of bacterial origin;GO:0016573//histone acetylation;GO:0033554//cellular response to stress;GO:0006366//transcription from RNA polymerase II promoter;GO:0032386//regulation of intracellular transport;GO:0033043//regulation of organelle organization;GO:0065003;GO:0006412//translation;GO:0012501//programmed cell death;GO:0009719;GO:0006355//regulation of transcription, DNA-templated" "gi|148685478|gb|EDL17425.1|/0/mCG22417, isoform CRA_b, partial [Mus musculus]" 110197 5521 0.186666667 0.166666667 -0.163498732 Down 0.102307345 Dgkg "diacylglycerol kinase, gamma" K00901|1|0.0|1609|mmu:110197|diacylglycerol kinase (ATP) [EC:2.7.1.107] GO:0044424;GO:0016020//membrane GO:0032550;GO:0046872//metal ion binding;GO:0016301//kinase activity GO:0006796//phosphate-containing compound metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030182//neuron differentiation gi|60360000|dbj|BAD90219.1|/0/mKIAA4131 protein [Mus musculus] 18478 2152 0.16 0.143333333 -0.158697746 Down 0.102307345 Pah phenylalanine hydroxylase K00500|1|0.0|895|mmu:18478|phenylalanine-4-hydroxylase [EC:1.14.16.1] - "GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0031406//carboxylic acid binding" GO:0006558//L-phenylalanine metabolic process;GO:0006570//tyrosine metabolic process;GO:0006464//cellular protein modification process;GO:0006732 gi|171543886|ref|NP_032803.2|/0/phenylalanine-4-hydroxylase [Mus musculus] 76044 6604 0.186666667 0.166666667 -0.163498732 Down 0.102307345 Ncapg2 "non-SMC condensin II complex, subunit G2" K11492|1|0.0|2241|mmu:76044|condensin-2 complex subunit G2 - - - gi|91208439|ref|NP_598523.3|/0/condensin-2 complex subunit G2 [Mus musculus] 100502734 2493 0.163333333 0.146666667 -0.155278225 Down 0.102307345 Gm16023 predicted gene 16023 "K15284|1|8e-27|125|mmu:320541|solute carrier family 35, member E2" - - - gi|28893193|ref|NP_796160.1|/6.67637e-26/solute carrier family 35 member E2 [Mus musculus] 71751 6709 0.16 0.143333333 -0.158697746 Down 0.102307345 Map3k13 mitogen-activated protein kinase kinase kinase 13 K04422|1|0.0|1600|mmu:71751|mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25] GO:0044424;GO:0043234//protein complex GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0032550;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0019900//kinase binding GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006468//protein phosphorylation;GO:0051403//stress-activated MAPK cascade gi|95113638|ref|NP_766409.2|/0/mitogen-activated protein kinase kinase kinase 13 [Mus musculus] 241688 6831 0.163333333 0.146666667 -0.155278225 Down 0.102307345 Dzank1 double zinc ribbon and ankyrin repeat domains 1 K17094|1|3e-18|98.2|crg:105344100|annexin A6;K17095|2|1e-16|92.8|sko:100376156|annexin A7/11;K18266|3|1e-14|53.5|cmk:103190398|protein NDRG1 GO:0044464 GO:0046914//transition metal ion binding - gi|124378024|ref|NP_766447.2|/0/double zinc ribbon and ankyrin repeat-containing protein 1 [Mus musculus] 330286 10986 0.223333333 0.2 -0.159198595 Down 0.102307345 D630045J12Rik RIKEN cDNA D630045J12 gene K16145|1|5e-08|65.1|tup:102484214| - - - gi|257467657|ref|NP_918950.2|/0/UPF0606 protein KIAA1549 precursor [Mus musculus] 70839 2338 0.166666667 0.186666667 0.163498732 Up 0.102307345 P2ry12 "purinergic receptor P2Y, G-protein coupled 12" "K04298|1|6e-170|600|mmu:70839|purinergic receptor P2Y, G protein-coupled, 12" GO:0043231//intracellular membrane-bounded organelle;GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane;GO:0009986//cell surface GO:0045028//G-protein coupled purinergic nucleotide receptor activity "GO:0035588;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0030168//platelet activation;GO:0006816//calcium ion transport;GO:0016043//cellular component organization;GO:0030154//cell differentiation;GO:0034220//ion transmembrane transport;GO:0014061//regulation of norepinephrine secretion;GO:0016477//cell migration" gi|169790983|ref|NP_081847.3|/5.02001e-169/P2Y purinoceptor 12 [Mus musculus] 347740 4930 48.67 49.09666667 0.012592304 Up 0.102232126 2900097C17Rik RIKEN cDNA 2900097C17 gene - - - - gi|26381879|dbj|BAC25475.1|/2.8879e-42/unnamed protein product [Mus musculus] 268527 7868 0.176666667 0.196666667 0.154722595 Up 0.102156907 Greb1 gene regulated by estrogen in breast cancer protein - - - - gi|154090987|ref|NP_056579.2|/0/protein GREB1 isoform 1 [Mus musculus] 217826 3061 0.18 0.2 0.152003093 Up 0.102156907 Kcnk13 "potassium channel, subfamily K, member 13" K04922|1|0.0|783|mmu:217826|potassium channel subfamily K member 13 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005261//cation channel activity;GO:0005261//cation channel activity;GO:0005261//cation channel activity GO:0034220//ion transmembrane transport;GO:0007267//cell-cell signaling;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0007267//cell-cell signaling;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0007267//cell-cell signaling;GO:0030001//metal ion transport gi|22122525|ref|NP_666149.1|/0/potassium channel subfamily K member 13 [Mus musculus] 268973 3838 0.173333333 0.156666667 -0.145850866 Down 0.102156907 Nlrc4 "NLR family, CARD domain containing 4" K12805|1|0.0|2013|mmu:268973|NLR family CARD domain-containing protein 4 GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0032550;GO:0046872//metal ion binding;GO:0042802//identical protein binding GO:0002253//activation of immune response;GO:0032611//interleukin-1 beta production;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0051259//protein oligomerization;GO:0030522//intracellular receptor signaling pathway;GO:0006952//defense response;GO:0009581 gi|77736546|ref|NP_001028539.1|/0/NLR family CARD domain-containing protein 4 [Mus musculus] 624367 1599 0.183333333 0.203333333 0.149377624 Up 0.102156907 Gm6498 glyceraldehyde-3-phosphate dehydrogenase pseudogene K00134|1|3e-127|370|shr:100916552|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0000166//nucleotide binding;GO:0015631//tubulin binding" GO:0006007//glucose catabolic process;GO:0012501//programmed cell death;GO:0070997//neuron death;GO:0044710;GO:0007010//cytoskeleton organization;GO:0031647//regulation of protein stability;GO:0018119//peptidyl-cysteine S-nitrosylation gi|821100513|ref|XP_012384730.1|/1.52179e-127/PREDICTED: LOW QUALITY PROTEIN: glyceraldehyde-3-phosphate dehydrogenase [Dasypus novemcinctus] 81879 9285 0.233333333 0.21 -0.152003093 Down 0.102156907 Tfcp2l1 transcription factor CP2-like 1 K09275|1|0.0|935|mmu:81879|transcription factor CP2 and related proteins GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0040007//growth;GO:0010259//multicellular organism aging;GO:0032989;GO:0006351//transcription, DNA-templated;GO:0035272//exocrine system development;GO:0002064//epithelial cell development" gi|134053939|ref|NP_076244.2|/0/transcription factor CP2-like protein 1 [Mus musculus] 72585 6159 0.18 0.2 0.152003093 Up 0.102156907 Lypd1 Ly6/Plaur domain containing 1 K08412|1|3e-85|320|mmu:71111|G protein-coupled receptor 39 - - - - 237979 6604 0.24 0.216666667 -0.147557188 Down 0.102156907 Sdk2 sidekick cell adhesion molecule 2 K16353|1|0.0|4204|mmu:237979|protein sidekick GO:0031224//intrinsic component of membrane - GO:0022610 gi|40254254|ref|NP_766388.2|/0/protein sidekick-2 precursor [Mus musculus] 73804 2792 0.203333333 0.183333333 -0.149377624 Down 0.102156907 Kif2c kinesin family member 2C K10393|1|0.0|1348|mmu:73804|kinesin family member 2/24 GO:0043231//intracellular membrane-bounded organelle;GO:0005874//microtubule;GO:0000776//kinetochore;GO:0043231//intracellular membrane-bounded organelle;GO:0005874//microtubule;GO:0000776//kinetochore GO:0008017//microtubule binding;GO:0032550;GO:0003774//motor activity;GO:0008017//microtubule binding;GO:0032550;GO:0003774//motor activity GO:0031109//microtubule polymerization or depolymerization;GO:0007059//chromosome segregation;GO:0000087//mitotic M phase;GO:0006928//movement of cell or subcellular component;GO:0031109//microtubule polymerization or depolymerization;GO:0007059//chromosome segregation;GO:0000087//mitotic M phase;GO:0006928//movement of cell or subcellular component gi|227430340|ref|NP_608301.3|/0/kinesin-like protein KIF2C isoform 1 [Mus musculus] 66433 688.8 80.42 80.83666667 0.007455497 Up 0.102109895 Chchd7 coiled-coil-helix-coiled-coil-helix domain containing 7 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0005740//mitochondrial envelope;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity;GO:0015002//heme-copper terminal oxidase activity - gi|31088924|ref|NP_852056.1|/1.8635e-44/coiled-coil-helix-coiled-coil-helix domain-containing protein 7 [Mus musculus] 18595 6553 4.683333333 4.606666667 -0.023812515 Down 0.102044078 Pdgfra "platelet derived growth factor receptor, alpha polypeptide" K04363|1|0.0|2064|mmu:18595|platelet-derived growth factor receptor alpha [EC:2.7.10.1] GO:0009986//cell surface;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane GO:0032550;GO:0042802//identical protein binding;GO:0005017//platelet-derived growth factor-activated receptor activity;GO:0019838//growth factor binding;GO:0070851//growth factor receptor binding;GO:0032550;GO:0042802//identical protein binding;GO:0005017//platelet-derived growth factor-activated receptor activity;GO:0019838//growth factor binding;GO:0070851//growth factor receptor binding GO:0008202//steroid metabolic process;GO:0048704//embryonic skeletal system morphogenesis;GO:0010543//regulation of platelet activation;GO:0008284//positive regulation of cell proliferation;GO:0048017//inositol lipid-mediated signaling;GO:0046546//development of primary male sexual characteristics;GO:0030239//myofibril assembly;GO:0043062//extracellular structure organization;GO:0010518//positive regulation of phospholipase activity;GO:0048546//digestive tract morphogenesis;GO:0072104//glomerular capillary formation;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0016477//cell migration;GO:0042476//odontogenesis;GO:0022008//neurogenesis;GO:0043200//response to amino acid;GO:0035270//endocrine system development;GO:0006935//chemotaxis;GO:0043627//response to estrogen;GO:0006260//DNA replication;GO:0036119//response to platelet-derived growth factor;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0008585//female gonad development;GO:0030323//respiratory tube development;GO:0043583//ear development;GO:0072497;GO:0006468//protein phosphorylation;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0008202//steroid metabolic process;GO:0048704//embryonic skeletal system morphogenesis;GO:0010543//regulation of platelet activation;GO:0008284//positive regulation of cell proliferation;GO:0048017//inositol lipid-mediated signaling;GO:0046546//development of primary male sexual characteristics;GO:0030239//myofibril assembly;GO:0043062//extracellular structure organization;GO:0010518//positive regulation of phospholipase activity;GO:0048546//digestive tract morphogenesis;GO:0072104//glomerular capillary formation;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0016477//cell migration;GO:0042476//odontogenesis;GO:0022008//neurogenesis;GO:0043200//response to amino acid;GO:0035270//endocrine system development;GO:0006935//chemotaxis;GO:0043627//response to estrogen;GO:0006260//DNA replication;GO:0036119//response to platelet-derived growth factor;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0008585//female gonad development;GO:0030323//respiratory tube development;GO:0043583//ear development;GO:0072497;GO:0006468//protein phosphorylation;GO:0051480//regulation of cytosolic calcium ion concentration "gi|148705936|gb|EDL37883.1|/0/platelet derived growth factor receptor, alpha polypeptide, isoform CRA_a, partial [Mus musculus]" 66482 4277 4.913333333 4.833333333 -0.023683624 Down 0.102044078 Exoc2 exocyst complex component 2 K17637|1|0.0|1756|mmu:66482|exocyst complex component 2 GO:0043234//protein complex;GO:0016020//membrane GO:0017016//Ras GTPase binding GO:0045184//establishment of protein localization;GO:0006887//exocytosis gi|21313438|ref|NP_079864.1|/0/exocyst complex component 2 [Mus musculus] 63873 3247 5.603333333 5.526666667 -0.019875718 Down 0.102044078 Trpv4 "transient receptor potential cation channel, subfamily V, member 4" K04973|1|0.0|1654|mmu:63873|transient receptor potential cation channel subfamily V member 4 GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0005874//microtubule;GO:0001726//ruffle;GO:0005924//cell-substrate adherens junction;GO:0031224//intrinsic component of membrane GO:0032550;GO:0019901//protein kinase binding;GO:0005261//cation channel activity;GO:0003779//actin binding;GO:0019904//protein domain specific binding;GO:0015631//tubulin binding;GO:0004888//transmembrane signaling receptor activity GO:0010975//regulation of neuron projection development;GO:0006972//hyperosmotic response;GO:0030036//actin cytoskeleton organization;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0034329//cell junction assembly;GO:0006971//hypotonic response;GO:0007165//signal transduction;GO:0030865//cortical cytoskeleton organization;GO:0030072//peptide hormone secretion;GO:0007019//microtubule depolymerization;GO:0070588//calcium ion transmembrane transport gi|269784723|ref|NP_071300.2|/0/transient receptor potential cation channel subfamily V member 4 [Mus musculus] 75725 3548.6 6.75 6.833333333 0.017702002 Up 0.102044078 Phf14 PHD finger protein 14 K11347|1|1e-30|138|mze:101474021|protein Jade-1;K05175|2|3e-30|137|ocu:100339376|gamma-aminobutyric acid receptor subunit alpha - GO:0046914//transition metal ion binding - gi|270288744|ref|NP_083680.2|/0/PHD finger protein 14 isoform 2 [Mus musculus] 223690 1894 5.016666667 5.093333333 0.021881056 Up 0.102044078 Ankrd54 ankyrin repeat domain 54 K18441|1|2e-15|87.0|aqu:100641148|cytohesin GO:0043231//intracellular membrane-bounded organelle GO:0019207//kinase regulator activity;GO:0005515//protein binding GO:0001932//regulation of protein phosphorylation;GO:0030218//erythrocyte differentiation;GO:0051169//nuclear transport gi|74150642|dbj|BAE25471.1|/3.08444e-170/unnamed protein product [Mus musculus] 12675 3483 5.543333333 5.466666667 -0.020092354 Down 0.102044078 Chuk conserved helix-loop-helix ubiquitous kinase K04467|1|0.0|1430|mmu:12675|inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10] GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0005887//integral component of plasma membrane;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0005887//integral component of plasma membrane;GO:0044444//cytoplasmic part GO:0032550;GO:0046983//protein dimerization activity;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0046983//protein dimerization activity;GO:0004674//protein serine/threonine kinase activity GO:0007265//Ras protein signal transduction;GO:0007589//body fluid secretion;GO:0002573//myeloid leukocyte differentiation;GO:0050673//epithelial cell proliferation;GO:0042476//odontogenesis;GO:0002009//morphogenesis of an epithelium;GO:0006468//protein phosphorylation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0042692//muscle cell differentiation;GO:0002237//response to molecule of bacterial origin;GO:0007265//Ras protein signal transduction;GO:0007589//body fluid secretion;GO:0002573//myeloid leukocyte differentiation;GO:0050673//epithelial cell proliferation;GO:0042476//odontogenesis;GO:0002009//morphogenesis of an epithelium;GO:0006468//protein phosphorylation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0042692//muscle cell differentiation;GO:0002237//response to molecule of bacterial origin gi|242332488|ref|NP_031726.2|/0/inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 [Mus musculus] 77128 7455 4.926666667 5.01 0.02419874 Up 0.102044078 Crebrf CREB3 regulatory factor - GO:0044451 GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0035966//response to topologically incorrect protein;GO:0009968//negative regulation of signal transduction;GO:0015031//protein transport;GO:0032386//regulation of intracellular transport;GO:0033554//cellular response to stress;GO:0009896 gi|30794196|ref|NP_084146.1|/0/CREB3 regulatory factor [Mus musculus] 71943 2093 6.873333333 6.79 -0.017598352 Down 0.102044078 Tom1l1 target of myb1-like 1 (chicken) K12404|1|1e-15|80.1|dre:100334661|ADP-ribosylation factor-binding protein GGA GO:0000323//lytic vacuole;GO:0031090//organelle membrane;GO:0044431//Golgi apparatus part GO:0019904//protein domain specific binding;GO:0032182//ubiquitin-like protein binding;GO:0019887//protein kinase regulator activity GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0015031//protein transport gi|25091359|sp|Q923U0.1|TM1L1_MOUSE/0/RecName: Full=TOM1-like protein 1; AltName: Full=Src-activating and signaling molecule protein; AltName: Full=Target of Myb-like protein 1 22757 3750.73 6.42 6.496666667 0.017126387 Up 0.102044078 Zkscan5 zinc finger with KRAB and SCAN domains 5 K09229|1|0.0|1692|mmu:22757|KRAB and SCAN domains-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0044764;GO:0006351//transcription, DNA-templated;GO:0044764;GO:0006351//transcription, DNA-templated" "gi|148687041|gb|EDL18988.1|/0/zinc finger protein 95, isoform CRA_b, partial [Mus musculus]" 72552 3183 6.636666667 6.713333333 0.016570462 Up 0.102044078 Hsdl1 hydroxysteroid dehydrogenase like 1 K10251|1|5e-64|249|sko:100371713|17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330] GO:0043231//intracellular membrane-bounded organelle GO:0036094//small molecule binding;GO:0003824//catalytic activity GO:0044710 gi|568957625|ref|XP_006531457.1|/0/PREDICTED: inactive hydroxysteroid dehydrogenase-like protein 1 isoform X3 [Mus musculus] 21843 4292 6.76 6.676666667 -0.017895231 Down 0.102044078 Tial1 Tia1 cytotoxic granule-associated RNA binding protein-like 1 K13201|1|0.0|760|rno:361655|nucleolysin TIA-1/TIAR GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule GO:0036094//small molecule binding;GO:0003723//RNA binding GO:0008283//cell proliferation;GO:0003006//developmental process involved in reproduction;GO:0012501//programmed cell death;GO:0051301//cell division gi|6678349|ref|NP_033409.1|/0/nucleolysin TIAR [Mus musculus] 209683 10702 5.493333333 5.576666667 0.021721203 Up 0.102044078 Ttc28 tetratricopeptide repeat domain 28 K15837|1|8e-53|213|clv:102087986|G-protein signaling modulator 2 - - - gi|390407654|ref|NP_001254551.1|/0/tetratricopeptide repeat protein 28 [Mus musculus] 21339 2430 7.6 7.52 -0.015266757 Down 0.102044078 Taf1a "TATA-box binding protein associated factor, RNA polymerase I, A" K15212|1|0.0|905|mmu:21339|TATA box-binding protein-associated factor RNA polymerase I subunit A GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|10946860|ref|NP_067441.1|/0/TATA box-binding protein-associated factor RNA polymerase I subunit A isoform 1 [Mus musculus] 54721 4822 5.77 5.853333333 0.02068712 Up 0.102044078 Tyk2 tyrosine kinase 2 K11219|1|0.0|2435|mmu:54721|non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2] GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0032550;GO:0005126//cytokine receptor binding;GO:0004713//protein tyrosine kinase activity;GO:0031701//angiotensin receptor binding;GO:0032550;GO:0005126//cytokine receptor binding;GO:0004713//protein tyrosine kinase activity;GO:0031701//angiotensin receptor binding GO:0035556//intracellular signal transduction;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0035556//intracellular signal transduction;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process gi|133922607|ref|NP_061263.2|/0/non-receptor tyrosine-protein kinase TYK2 isoform 2 [Mus musculus] 16582 3318.91 53.67 53.26333333 -0.01097317 Down 0.102006469 Kifc3 kinesin family member C3 K10406|1|0.0|1552|mmu:16582|kinesin family member C2/C3 GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0005913//cell-cell adherens junction GO:0003777//microtubule motor activity;GO:0032550 GO:0006996//organelle organization;GO:0016337//single organismal cell-cell adhesion;GO:0045217//cell-cell junction maintenance;GO:0006928//movement of cell or subcellular component gi|568956236|ref|XP_006530786.1|/0/PREDICTED: kinesin-like protein KIFC3 isoform X5 [Mus musculus] 19744 1521 44.37 44.77666667 0.01316258 Up 0.102006469 Rheb Ras homolog enriched in brain K07208|1|2e-97|358|ngi:103745322|Ras homolog enriched in brain GO:0043005//neuron projection;GO:0016020//membrane;GO:0044297//cell body;GO:0044444//cytoplasmic part;GO:0030529//intracellular ribonucleoprotein complex GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0043169//cation binding;GO:0019900//kinase binding GO:0048167//regulation of synaptic plasticity;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009967//positive regulation of signal transduction;GO:0022402//cell cycle process;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction gi|28626508|ref|NP_444305.2|/1.4743e-96/GTP-binding protein Rheb precursor [Mus musculus] 52468 4792.86 56.10666667 56.50666667 0.010248883 Up 0.101950055 Ctdsp2 "CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2" K15731|1|7e-73|278|mmu:52468|carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16] GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen GO:0043169//cation binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0043169//cation binding;GO:0004722//protein serine/threonine phosphatase activity GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0006796//phosphate-containing compound metabolic process gi|164698411|ref|NP_001106941.1|/9.39761e-147/carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 isoform a [Mus musculus] 140577 4444 0.56 0.586666667 0.067114196 Up 0.101874835 Ankrd6 ankyrin repeat domain 6 K15503|1|5e-35|153|aag:AaeL_AAEL014668|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0030178//negative regulation of Wnt signaling pathway;GO:2000052//positive regulation of non-canonical Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:2000052//positive regulation of non-canonical Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:2000052//positive regulation of non-canonical Wnt signaling pathway gi|50510725|dbj|BAD32348.1|/0/mKIAA0957 protein [Mus musculus] 20555 1881 0.55 0.576666667 0.068306013 Up 0.101874835 Slfn1 schlafen 1 - GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001932//regulation of protein phosphorylation;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0042098//T cell proliferation gi|6755568|ref|NP_035537.1|/0/schlafen 1 [Mus musculus] 77125 2534 0.636666667 0.666666667 0.066427362 Up 0.101874835 Il33 interleukin 33 K12967|1|9e-151|536|mmu:77125|interleukin 33 "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0043232;GO:0044421;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0043232;GO:0044421" GO:0005102//receptor binding;GO:0005102//receptor binding GO:0032722//positive regulation of chemokine production;GO:0006366//transcription from RNA polymerase II promoter;GO:0001818//negative regulation of cytokine production;GO:0048305//immunoglobulin secretion;GO:0002696//positive regulation of leukocyte activation;GO:0002823;GO:0006954//inflammatory response;GO:0002828//regulation of type 2 immune response;GO:0032722//positive regulation of chemokine production;GO:0006366//transcription from RNA polymerase II promoter;GO:0001818//negative regulation of cytokine production;GO:0048305//immunoglobulin secretion;GO:0002696//positive regulation of leukocyte activation;GO:0002823;GO:0006954//inflammatory response;GO:0002828//regulation of type 2 immune response gi|257900486|ref|NP_598536.2|/7.5012e-150/interleukin-33 precursor [Mus musculus] 72119 4161.17 0.67 0.636666667 -0.073622863 Down 0.101874835 Tpx2 "TPX2, microtubule-associated" K16812|1|0.0|1378|mmu:72119|targeting protein for Xklp2 GO:0005819//spindle;GO:0005819//spindle;GO:0005819//spindle;GO:0005819//spindle;GO:0005819//spindle GO:0019900//kinase binding;GO:0019900//kinase binding;GO:0019900//kinase binding;GO:0019900//kinase binding;GO:0019900//kinase binding GO:0012501//programmed cell death;GO:0000087//mitotic M phase;GO:0007052//mitotic spindle organization;GO:0006461//protein complex assembly;GO:0045860//positive regulation of protein kinase activity;GO:0012501//programmed cell death;GO:0000087//mitotic M phase;GO:0007052//mitotic spindle organization;GO:0006461//protein complex assembly;GO:0045860//positive regulation of protein kinase activity;GO:0012501//programmed cell death;GO:0000087//mitotic M phase;GO:0007052//mitotic spindle organization;GO:0006461//protein complex assembly;GO:0045860//positive regulation of protein kinase activity;GO:0012501//programmed cell death;GO:0000087//mitotic M phase;GO:0007052//mitotic spindle organization;GO:0006461//protein complex assembly;GO:0045860//positive regulation of protein kinase activity;GO:0012501//programmed cell death;GO:0000087//mitotic M phase;GO:0007052//mitotic spindle organization;GO:0006461//protein complex assembly;GO:0045860//positive regulation of protein kinase activity "gi|148674048|gb|EDL05995.1|/0/TPX2, microtubule-associated protein homolog (Xenopus laevis), isoform CRA_b, partial [Mus musculus]" 75698 3463 0.526666667 0.553333333 0.071258683 Up 0.101874835 Fam35a "family with sequence similarity 35, member A" - - - - gi|122891876|ref|NP_083665.2|/0/protein FAM35A [Mus musculus] 76229 1609 0.626666667 0.596666667 -0.070773074 Down 0.101874835 Vmn2r29 "vomeronasal 2, receptor 29" K04613|1|0.0|1678|mmu:76229|vomeronasal 2 receptor GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway "gi|164698709|ref|NP_001106939.1|/1.44662e-65/vomeronasal 2, receptor 29 precursor [Mus musculus]" 73467 3008 0.653333333 0.623333333 -0.067815384 Down 0.101874835 1700066M21Rik RIKEN cDNA 1700066M21 gene - - - - gi|256355005|ref|NP_082822.1|/0/UPF0565 protein C2orf69 homolog precursor [Mus musculus] 100502766 2330 0.673333333 0.706666667 0.069708972 Up 0.101874835 Kifc1 kinesin family member C1 K10405|1|0.0|1180|mmu:100502766|kinesin family member C1 GO:0015630//microtubule cytoskeleton;GO:0005768//endosome GO:0032550;GO:0003774//motor activity GO:0000087//mitotic M phase;GO:0006928//movement of cell or subcellular component gi|305678350|ref|NP_001182227.1|/0/kinesin-like protein KIFC1 [Mus musculus] 192897 6160 0.553333333 0.526666667 -0.071258683 Down 0.101874835 Itgb4 integrin beta 4 K06525|1|0.0|3425|mmu:192897|integrin beta 4 GO:0030055//cell-substrate junction;GO:0044444//cytoplasmic part;GO:0016323//basolateral plasma membrane;GO:0005578//proteinaceous extracellular matrix;GO:0005887//integral component of plasma membrane;GO:0030055//cell-substrate junction;GO:0044444//cytoplasmic part;GO:0016323//basolateral plasma membrane;GO:0005578//proteinaceous extracellular matrix;GO:0005887//integral component of plasma membrane GO:0005515//protein binding;GO:0005515//protein binding GO:0007044//cell-substrate junction assembly;GO:0007166//cell surface receptor signaling pathway;GO:0006928//movement of cell or subcellular component;GO:0032502//developmental process;GO:0006950//response to stress;GO:0031589//cell-substrate adhesion;GO:0030031//cell projection assembly;GO:0007044//cell-substrate junction assembly;GO:0007166//cell surface receptor signaling pathway;GO:0006928//movement of cell or subcellular component;GO:0032502//developmental process;GO:0006950//response to stress;GO:0031589//cell-substrate adhesion;GO:0030031//cell projection assembly gi|110735428|ref|NP_598424.2|/0/integrin beta-4 isoform 2 precursor [Mus musculus] 55984 3466 0.543333333 0.516666667 -0.072603749 Down 0.101874835 Camkk1 "calcium/calmodulin-dependent protein kinase kinase 1, alpha" K07359|1|0.0|1022|mmu:55984|calcium/calmodulin-dependent protein kinase kinase [EC:2.7.11.17] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding GO:0045860//positive regulation of protein kinase activity gi|133922603|ref|NP_061371.2|/0/calcium/calmodulin-dependent protein kinase kinase 1 [Mus musculus] 170744 4377.79 0.603333333 0.576666667 -0.065217659 Down 0.101874835 Tlr8 toll-like receptor 8 K10170|1|0.0|2009|mmu:170744|toll-like receptor 8 - - - - 68465 3963 40.94666667 41.33666667 0.013676045 Up 0.101865433 Adipor2 adiponectin receptor 2 K07297|1|0.0|792|mmu:68465|adiponectin receptor GO:0031224//intrinsic component of membrane GO:0046983//protein dimerization activity GO:0006631//fatty acid metabolic process;GO:0044703;GO:0016049//cell growth;GO:0031667//response to nutrient levels;GO:0044767//single-organism developmental process;GO:0010828//positive regulation of glucose transport;GO:0007165//signal transduction gi|39841016|ref|NP_932102.2|/0/adiponectin receptor protein 2 [Mus musculus] 224647 3779.22 68.51666667 68.14 -0.007953019 Down 0.101799616 D17Wsu92e "DNA segment, Chr 17, Wayne State University 92, expressed" K17987|1|5e-11|73.2|crg:105321000|next to BRCA1 gene 1 protein - - - - 67615 3312 53.17666667 53.55666667 0.010272825 Up 0.101799616 Ube2r2 ubiquitin-conjugating enzyme E2R 2 K02207|1|8e-110|401|pale:102898351|ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0019787//ubiquitin-like protein transferase activity GO:0006511//ubiquitin-dependent protein catabolic process;GO:0009968//negative regulation of signal transduction;GO:0000209//protein polyubiquitination gi|942076437|ref|XP_005903088.2|/6.70596e-109/PREDICTED: ubiquitin-conjugating enzyme E2 R2 [Bos mutus] 230857 4856 38.72 39.10333333 0.014212642 Up 0.101799616 Ece1 endothelin converting enzyme 1 K01415|1|0.0|1510|mmu:230857|endothelin-converting enzyme [EC:3.4.24.71] GO:0030141//secretory granule;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0005768//endosome GO:0004175//endopeptidase activity;GO:0042802//identical protein binding;GO:0043169//cation binding GO:0007186//G-protein coupled receptor signaling pathway;GO:0007423//sensory organ development;GO:0001881//receptor recycling;GO:0012501//programmed cell death;GO:0030326//embryonic limb morphogenesis;GO:0043009//chordate embryonic development;GO:0016485//protein processing;GO:0034754;GO:0010813//neuropeptide catabolic process;GO:0002002//regulation of angiotensin levels in blood gi|67810530|gb|AAY81996.1|/0/endothelin-converting enzyme-1d [Mus musculus] 66096 900 36.35666667 35.99 -0.014623831 Down 0.101686788 Lamtor4 "late endosomal/lysosomal adaptor, MAPK and MTOR activator 4" K20399|1|1e-48|195|ssc:100526100|ragulator complex protein LAMTOR4 GO:0000323//lytic vacuole;GO:0031902//late endosome membrane - GO:0009967//positive regulation of signal transduction;GO:0032535//regulation of cellular component size;GO:0072665//protein localization to vacuole;GO:0043200//response to amino acid "gi|148687256|gb|EDL19203.1|/1.99303e-61/mCG7441, isoform CRA_a, partial [Mus musculus]" 66855 3008.92 77.34666667 77.71333333 0.006823026 Up 0.101686788 Tcf25 transcription factor 25 (basic helix-loop-helix) "K14206|1|6e-46|189|bmor:101737920|solute carrier family 15 (oligopeptide transporter), member 1" GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148679789|gb|EDL11736.1|/0/transcription factor 25 (basic helix-loop-helix), isoform CRA_b, partial [Mus musculus]" 53419 4774 43.41 43.77 0.011914961 Up 0.101592764 Corin corin K09614|1|0.0|2204|mmu:53419|corin [EC:3.4.21.-] GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane GO:0004175//endopeptidase activity;GO:0008236//serine-type peptidase activity;GO:0038024//cargo receptor activity;GO:0004175//endopeptidase activity;GO:0008236//serine-type peptidase activity;GO:0038024//cargo receptor activity GO:0044703;GO:0001990//regulation of systemic arterial blood pressure by hormone;GO:0035812;GO:0030154//cell differentiation;GO:0016485//protein processing;GO:0044703;GO:0001990//regulation of systemic arterial blood pressure by hormone;GO:0035812;GO:0030154//cell differentiation;GO:0016485//protein processing gi|170295825|ref|NP_058565.2|/0/atrial natriuretic peptide-converting enzyme isoform 1 [Mus musculus] 11490 2921.67 55.00666667 55.37 0.009498042 Up 0.101592764 Adam15 a disintegrin and metallopeptidase domain 15 (metargidin) K06836|1|0.0|1501|mmu:11490|disintegrin and metalloproteinase domain-containing protein 15 [EC:3.4.24.-] GO:0031224//intrinsic component of membrane;GO:0070161;GO:0030141//secretory granule;GO:0031224//intrinsic component of membrane;GO:0070161;GO:0030141//secretory granule GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding GO:0001837//epithelial to mesenchymal transition;GO:0019538//protein metabolic process;GO:0007155//cell adhesion;GO:0032963//collagen metabolic process;GO:0001837//epithelial to mesenchymal transition;GO:0019538//protein metabolic process;GO:0007155//cell adhesion;GO:0032963//collagen metabolic process "gi|148683260|gb|EDL15207.1|/0/a disintegrin and metallopeptidase domain 15 (metargidin), isoform CRA_a, partial [Mus musculus]" 214597 4244.84 35.97333333 35.61666667 -0.014375345 Down 0.101592764 Sidt2 "SID1 transmembrane family, member 2" - GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane GO:0051032;GO:0051032 GO:0044765//single-organism transport;GO:0035194//posttranscriptional gene silencing by RNA;GO:0044765//single-organism transport;GO:0035194//posttranscriptional gene silencing by RNA "gi|148693723|gb|EDL25670.1|/0/SID1 transmembrane family, member 2, isoform CRA_c, partial [Mus musculus]" 70315 1736 2.41 2.363333333 -0.02821002 Down 0.101573959 Hdac8 histone deacetylase 8 K11405|1|0.0|775|fca:101096383|histone deacetylase 8 [EC:3.5.1.98] - - - - 13666 4519 2.623333333 2.576666667 -0.025895222 Down 0.101573959 Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 K08860|1|0.0|1889|rno:29702|eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1] - - - - 621976 7170 2.206666667 2.256666667 0.032324617 Up 0.101573959 Tmem170b transmembrane protein 170B - GO:0031224//intrinsic component of membrane - - gi|254675263|ref|NP_001157044.1|/1.24146e-65/transmembrane protein 170B [Mus musculus] 225895 2203 3.02 2.966666667 -0.025705714 Down 0.101573959 Taf6l TATA-box binding protein associated factor 6 like K03131|1|0.0|1220|mmu:225895|transcription initiation factor TFIID subunit 6 GO:0070461//SAGA-type complex;GO:0070461//SAGA-type complex GO:0008080//N-acetyltransferase activity;GO:0046983//protein dimerization activity;GO:0008080//N-acetyltransferase activity;GO:0046983//protein dimerization activity "GO:0006355//regulation of transcription, DNA-templated;GO:0016573//histone acetylation;GO:0006355//regulation of transcription, DNA-templated;GO:0016573//histone acetylation" "gi|148701423|gb|EDL33370.1|/0/TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, isoform CRA_b, partial [Mus musculus]" 327744 1664 2.223333333 2.173333333 -0.032814797 Down 0.101573959 E130307A14Rik RIKEN cDNA E130307A14 gene - - - - - 59036 3709.83 2.136666667 2.183333333 0.03117055 Up 0.101573959 Dact1 dishevelled-binding antagonist of beta-catenin 1 - - - - - 68431 1365 2.91 2.856666667 -0.02668645 Down 0.101573959 Fbxl15 F-box and leucine-rich repeat protein 15 K10281|1|7e-159|562|mmu:68431|F-box and leucine-rich repeat protein 15 GO:0031461//cullin-RING ubiquitin ligase complex GO:0019787//ubiquitin-like protein transferase activity GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0003002//regionalization;GO:0001503//ossification;GO:0032446//protein modification by small protein conjugation;GO:0044772//mitotic cell cycle phase transition;GO:0030509//BMP signaling pathway gi|140970874|ref|NP_598455.2|/5.78577e-158/F-box/LRR-repeat protein 15 [Mus musculus] 237988 3700 2.88 2.83 -0.025266759 Down 0.101573959 Cdr2l cerebellar degeneration-related protein 2-like - - - - - 19130 4148 2.726666667 2.676666667 -0.026700855 Down 0.101573959 Prox1 prospero homeobox 1 K20211|1|0.0|1314|mmu:19130|prospero homeobox 1 GO:0043231//intracellular membrane-bounded organelle "GO:0005102//receptor binding;GO:0003712//transcription cofactor activity;GO:0019904//protein domain specific binding;GO:0000975//regulatory region DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding" GO:0021766//hippocampus development;GO:0007015//actin filament organization;GO:0001935//endothelial cell proliferation;GO:0003160//endocardium morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0021879//forebrain neuron differentiation;GO:0019079//viral genome replication;GO:0035909//aorta morphogenesis;GO:0000084//mitotic S phase;GO:0060838//lymphatic endothelial cell fate commitment;GO:0090068//positive regulation of cell cycle process;GO:0000904//cell morphogenesis involved in differentiation;GO:0045214//sarcomere organization;GO:0046622//positive regulation of organ growth;GO:0072575;GO:0003281//ventricular septum development;GO:0003209//cardiac atrium morphogenesis;GO:0010594//regulation of endothelial cell migration;GO:0002088//lens development in camera-type eye;GO:0021533//cell differentiation in hindbrain;GO:0044092//negative regulation of molecular function;GO:0006366//transcription from RNA polymerase II promoter;GO:0055003//cardiac myofibril assembly;GO:0043583//ear development;GO:0019827//stem cell population maintenance;GO:0006699//bile acid biosynthetic process;GO:0003208//cardiac ventricle morphogenesis gi|466035766|ref|XP_004275294.1|/0/PREDICTED: prospero homeobox protein 1 [Orcinus orca] 20272 7333 2.116666667 2.07 -0.032163323 Down 0.101573959 Scn7a "sodium channel, voltage-gated, type VII, alpha" K04839|1|0.0|3229|mmu:20272|voltage-gated sodium channel type VII alpha GO:0005887//integral component of plasma membrane GO:0005272//sodium channel activity GO:0030001//metal ion transport gi|157058300|ref|NP_033161.2|/0/sodium channel protein type 7 subunit alpha [Mus musculus] 242418 7226 2.416666667 2.363333333 -0.032195368 Down 0.101573959 Dcaf10 DDB1 and CUL4 associated factor 10 K11802|1|0.0|922|mmu:242418|WD repeat-containing protein 32 GO:0031461//cullin-RING ubiquitin ligase complex - - gi|110815804|ref|NP_694807.2|/0/DDB1- and CUL4-associated factor 10 [Mus musculus] 22411 2888.15 2.256666667 2.21 -0.030146963 Down 0.101573959 Wnt11 "wingless-type MMTV integration site family, member 11" "K01384|1|5e-103|213|mgp:100544486|wingless-type MMTV integration site family, member 11" GO:0044424;GO:0005576//extracellular region;GO:0031012//extracellular matrix GO:0005515//protein binding;GO:0000975//regulatory region DNA binding;GO:0019887//protein kinase regulator activity "GO:0006915//apoptotic process;GO:0016049//cell growth;GO:0006351//transcription, DNA-templated;GO:0001503//ossification;GO:0016477//cell migration;GO:0032906;GO:0001934//positive regulation of protein phosphorylation;GO:0003281//ventricular septum development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0003007//heart morphogenesis;GO:0030154//cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0032233//positive regulation of actin filament bundle assembly;GO:0007043//cell-cell junction assembly;GO:0048514//blood vessel morphogenesis;GO:0034613//cellular protein localization;GO:0001818//negative regulation of cytokine production" gi|6678589|ref|NP_033545.1|/0/protein Wnt-11 isoform a precursor [Mus musculus] 229584 7630.71 2.62 2.666666667 0.025470688 Up 0.101573959 Pogz pogo transposable element with ZNF domain K08776|1|3e-25|121|cmk:103185706|puromycin-sensitive aminopeptidase [EC:3.4.11.-];K10500|2|4e-15|88.2|cge:100754046|zinc finger and BTB domain-containing protein 17 GO:0031981//nuclear lumen;GO:0043232;GO:0031981//nuclear lumen;GO:0043232 GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0000070//mitotic sister chromatid segregation;GO:0034508//centromere complex assembly;GO:0000070//mitotic sister chromatid segregation;GO:0034508//centromere complex assembly gi|260099684|ref|NP_766271.2|/0/pogo transposable element with ZNF domain isoform 1 [Mus musculus] 69663 4874 1.976666667 2.023333333 0.033664412 Up 0.101573959 Ddx51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 K14807|1|0.0|1198|mmu:69663|ATP-dependent RNA helicase DDX51/DBP6 [EC:3.6.4.13] GO:0031981//nuclear lumen "GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled" GO:0042254//ribosome biogenesis gi|40538825|ref|NP_081432.2|/0/ATP-dependent RNA helicase DDX51 [Mus musculus] 66120 799 2.426666667 2.373333333 -0.032061209 Down 0.101573959 Fkbp11 FK506 binding protein 11 K09576|1|3e-86|320|mmu:66120|FK506-binding protein 11 [EC:5.2.1.8] - - - gi|15277331|ref|NP_077131.2|/2.70666e-85/peptidyl-prolyl cis-trans isomerase FKBP11 precursor [Mus musculus] 237847 3308 2.306666667 2.36 0.032977322 Up 0.101573959 Rtn4rl1 reticulon 4 receptor-like 1 K16660|1|0.0|863|mmu:237847|reticulon-4 receptor-like 1 GO:0009986//cell surface;GO:0031225//anchored component of membrane - GO:0007409//axonogenesis;GO:0007165//signal transduction gi|29244160|ref|NP_808376.1|/0/reticulon-4 receptor-like 1 precursor [Mus musculus] 100986 12105 2.506666667 2.56 0.030373649 Up 0.101573959 Akap9 A kinase (PRKA) anchor protein (yotiao) 9 K16551|1|0.0|6420|mmu:100986|A-kinase anchor protein 9 - - - "gi|148682679|gb|EDL14626.1|/0/A kinase (PRKA) anchor protein (yotiao) 9, isoform CRA_b, partial [Mus musculus]" 12807 3868.9 2.63 2.68 0.027170201 Up 0.101573959 Hps3 Hermansky-Pudlak syndrome 3 K20190|1|0.0|1106|mmu:12807|Hermansky-Pudlak syndrome 3 protein - - - - 235504 3241 2.513333333 2.566666667 0.030293922 Up 0.101573959 Slc17a5 "solute carrier family 17 (anion/sugar transporter), member 5" "K12301|1|0.0|984|mmu:235504|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 5" GO:0005764//lysosome;GO:0016021//integral component of membrane;GO:0008021//synaptic vesicle;GO:0005764//lysosome;GO:0016021//integral component of membrane;GO:0008021//synaptic vesicle GO:0005402//cation:sugar symporter activity;GO:0046943//carboxylic acid transmembrane transporter activity;GO:0005402//cation:sugar symporter activity;GO:0046943//carboxylic acid transmembrane transporter activity GO:0044763;GO:0046942//carboxylic acid transport;GO:0044763;GO:0046942//carboxylic acid transport gi|27370146|ref|NP_766361.1|/0/sialin isoform a [Mus musculus] 12267 4299 2.693333333 2.64 -0.028854863 Down 0.101573959 C3ar1 complement component 3a receptor 1 K04009|1|0.0|857|mmu:12267|C3a anaphylatoxin chemotactic receptor GO:0031224//intrinsic component of membrane GO:0004942//anaphylatoxin receptor activity;GO:0001848//complement binding GO:0001525//angiogenesis;GO:0002461;GO:0008015//blood circulation;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0001819//positive regulation of cytokine production;GO:0002429//immune response-activating cell surface receptor signaling pathway gi|6753224|ref|NP_033909.1|/0/C3a anaphylatoxin chemotactic receptor [Mus musculus] 15574 4652.44 2.33 2.376666667 0.028609621 Up 0.101573959 Hus1 HUS1 checkpoint clamp component K10903|1|8e-144|514|mmu:15574|HUS1 checkpoint protein - - - - 242585 2893 2.29 2.236666667 -0.033997333 Down 0.101573959 Slc35d1 "solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1" K15281|1|3e-170|602|mmu:242585|solute carrier family 35 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system GO:0005338//nucleotide-sugar transmembrane transporter activity GO:0006024//glycosaminoglycan biosynthetic process;GO:0001501//skeletal system development;GO:0044765//single-organism transport gi|29244214|ref|NP_808400.1|/2.21865e-169/UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter [Mus musculus] 320799 4499 2.263333333 2.213333333 -0.032228333 Down 0.101573959 Zhx3 zinc fingers and homeoboxes 3 K09378|1|8e-07|59.7|xma:102224631|AT-binding transcription factor 1 GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0003712//transcription cofactor activity;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity "GO:0001649//osteoblast differentiation;GO:0006351//transcription, DNA-templated" gi|40254321|ref|NP_796237.2|/0/zinc fingers and homeoboxes protein 3 [Mus musculus] 210126 15669 2.433333333 2.486666667 0.031279166 Up 0.101573959 Lpp LIM domain containing preferred translocation partner in lipoma K16676|1|0.0|881|mmu:210126|lipoma-prefererred partner GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0005924//cell-substrate adherens junction;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0022610;GO:0022610;GO:0022610 gi|225543157|ref|NP_848780.3|/0/lipoma-preferred partner homolog isoform 1 [Mus musculus] 14312 4380.62 35.78333333 36.13 0.013909469 Up 0.101461131 Brd2 bromodomain containing 2 K08871|1|0.0|1004|mmu:14312|bromodomain-containing protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0042393//histone binding;GO:0042393//histone binding;GO:0042393//histone binding GO:0034728//nucleosome organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0034728//nucleosome organization;GO:0006366//transcription from RNA polymerase II promoter;GO:0034728//nucleosome organization;GO:0006366//transcription from RNA polymerase II promoter gi|71067345|ref|NP_034368.2|/0/bromodomain-containing protein 2 [Mus musculus] 320405 4663 0.23 0.253333333 0.139403057 Up 0.101432923 Cadps2 Ca2+-dependent activator protein for secretion 2 K19933|1|0.0|2334|mmu:320405|calcium-dependent secretion activator GO:0030136//clathrin-coated vesicle;GO:0097060//synaptic membrane;GO:0030136//clathrin-coated vesicle;GO:0097060//synaptic membrane;GO:0030136//clathrin-coated vesicle;GO:0097060//synaptic membrane;GO:0030136//clathrin-coated vesicle;GO:0097060//synaptic membrane;GO:0030136//clathrin-coated vesicle;GO:0097060//synaptic membrane;GO:0030136//clathrin-coated vesicle;GO:0097060//synaptic membrane;GO:0030136//clathrin-coated vesicle;GO:0097060//synaptic membrane GO:0043169//cation binding;GO:0008289//lipid binding;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0008289//lipid binding;GO:0043169//cation binding;GO:0008289//lipid binding GO:0016079//synaptic vesicle exocytosis;GO:0045184//establishment of protein localization;GO:0016079//synaptic vesicle exocytosis;GO:0045184//establishment of protein localization;GO:0016079//synaptic vesicle exocytosis;GO:0045184//establishment of protein localization;GO:0016079//synaptic vesicle exocytosis;GO:0045184//establishment of protein localization;GO:0016079//synaptic vesicle exocytosis;GO:0045184//establishment of protein localization;GO:0016079//synaptic vesicle exocytosis;GO:0016079//synaptic vesicle exocytosis;GO:0045184//establishment of protein localization gi|355390345|ref|NP_001239037.1|/0/calcium-dependent secretion activator 2 isoform 5 [Mus musculus] 12075 2414 0.25 0.226666667 -0.141355849 Down 0.101432923 Bfsp1 "beaded filament structural protein 1, in lens-CP94" K10378|1|0.0|1131|mmu:12075|filensin GO:0005856//cytoskeleton;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0005488//binding;GO:0005198//structural molecule activity;GO:0005488//binding;GO:0005198//structural molecule activity GO:0048468//cell development;GO:0021700//developmental maturation;GO:0048468//cell development;GO:0021700//developmental maturation gi|66792790|ref|NP_033881.2|/0/filensin isoform b [Mus musculus] 327799 2946 0.2 0.22 0.137503524 Up 0.101432923 Usp44 ubiquitin specific peptidase 44 K11834|1|0.0|772|mmu:327799|ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12] - - - gi|332205971|ref|NP_001193780.1|/0/ubiquitin carboxyl-terminal hydrolase 44 isoform 1 [Mus musculus] 104174 3792 0.246666667 0.223333333 -0.143364175 Down 0.101432923 Gldc glycine decarboxylase K00281|1|0.0|1875|mmu:104174|glycine dehydrogenase [EC:1.4.4.2] GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle GO:0042802//identical protein binding;GO:0016597//amino acid binding;GO:0016642 GO:0006546//glycine catabolic process "gi|148709755|gb|EDL41701.1|/0/glycine decarboxylase, isoform CRA_d, partial [Mus musculus]" 68014 2784 0.193333333 0.213333333 0.142019005 Up 0.101432923 Zwilch zwilch kinetochore protein K11579|1|0.0|1163|mmu:68014|protein zwilch "GO:0000775//chromosome, centromeric region" - GO:0000075//cell cycle checkpoint;GO:0000087//mitotic M phase gi|257153357|ref|NP_080783.3|/0/protein zwilch homolog [Mus musculus] 74927 720 0.233333333 0.256666667 0.137503524 Up 0.101432923 Pmis2 "Pmis2, sperm specific protein" - - - - - 14687 2435 0.22 0.2 -0.137503524 Down 0.101432923 Gnaz "guanine nucleotide binding protein, alpha z subunit" K04535|1|0.0|666|cge:100767381|guanine nucleotide-binding protein G(z) subunit alpha - - - gi|880886727|ref|XP_005070823.2|/0/PREDICTED: guanine nucleotide-binding protein G(z) subunit alpha [Mesocricetus auratus] 245902 3525 0.203333333 0.223333333 0.135351853 Up 0.101432923 Ccdc15 coiled-coil domain containing 15 K16752|1|0.0|1504|mmu:245902|coiled-coil domain-containing protein 15 - - - gi|124487469|ref|NP_001074898.1|/0/coiled-coil domain-containing protein 15 [Mus musculus] 19826 1815.57 49.98666667 50.33 0.009875273 Up 0.101367107 Rnps1 ribonucleic acid binding protein S1 K14325|1|2e-43|179|shr:100919922|RNA-binding protein with serine-rich domain 1 GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body GO:0003729//mRNA binding;GO:0036094//small molecule binding;GO:0003729//mRNA binding;GO:0036094//small molecule binding;GO:0003729//mRNA binding;GO:0036094//small molecule binding GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006396//RNA processing;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006396//RNA processing;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006396//RNA processing gi|940782404|ref|XP_014306004.1|/1.15702e-50/PREDICTED: LOW QUALITY PROTEIN: RNA-binding protein with serine-rich domain 1-like [Myotis lucifugus] 94184 3788.28 42.62666667 42.96333333 0.011349687 Up 0.101367107 Pdxdc1 pyridoxal-dependent decarboxylase domain containing 1 K01580|1|9e-13|79.0|crg:105321902|glutamate decarboxylase [EC:4.1.1.15];K01594|2|7e-10|69.3|dgr:Dgri_GH16827|sulfinoalanine decarboxylase [EC:4.1.1.29];K18966|3|3e-09|67.4|ngi:103744638|sulfinoalanine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.29 4.1.1.11] - - - "gi|148664964|gb|EDK97380.1|/0/mCG129810, isoform CRA_b, partial [Mus musculus]" 18032 5624.29 62.64 62.30333333 -0.007774861 Down 0.101367107 Nfix nuclear factor I/X K09171|1|0.0|735|rno:81524|nuclear factor I/X GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003676//nucleic acid binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding" GO:0006259//DNA metabolic process;GO:0021695//cerebellar cortex development;GO:0021533//cell differentiation in hindbrain;GO:0006366//transcription from RNA polymerase II promoter;GO:0006259//DNA metabolic process;GO:0021695//cerebellar cortex development;GO:0021533//cell differentiation in hindbrain;GO:0006366//transcription from RNA polymerase II promoter;GO:0006259//DNA metabolic process;GO:0021695//cerebellar cortex development;GO:0021533//cell differentiation in hindbrain;GO:0006366//transcription from RNA polymerase II promoter gi|56549649|ref|NP_002492.2|/0/nuclear factor 1 X-type isoform 2 [Homo sapiens] 78541 2168.11 52.32666667 51.99333333 -0.009219708 Down 0.10126368 Asb8 ankyrin repeat and SOCS box-containing 8 K10330|1|2e-160|568|mmu:78541|ankyrin repeat and SOCS box protein 8 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation;GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation;GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation gi|282397100|ref|NP_084397.3|/1.47172e-159/ankyrin repeat and SOCS box protein 8 [Mus musculus] 68592 1276 49.16666667 48.83333333 -0.00981429 Down 0.10126368 Syf2 "SYF2 homolog, RNA splicing factor (S. cerevisiae)" K12868|1|5e-116|420|mmu:68592|pre-mRNA-splicing factor SYF2 GO:0005681//spliceosomal complex - GO:0043009//chordate embryonic development;GO:0048598//embryonic morphogenesis;GO:0006396//RNA processing gi|21312064|ref|NP_081056.1|/4.20255e-115/pre-mRNA-splicing factor SYF2 [Mus musculus] 19042 2789 57.74333333 57.41333333 -0.008268573 Down 0.10126368 Ppm1a "protein phosphatase 1A, magnesium dependent, alpha isoform" K04457|1|0.0|787|cge:100773654|protein phosphatase 1A [EC:3.1.3.16] GO:0034704//calcium channel complex;GO:0043231//intracellular membrane-bounded organelle;GO:0042995//cell projection GO:0046914//transition metal ion binding;GO:0060089;GO:0004723//calcium-dependent protein serine/threonine phosphatase activity;GO:0046332//SMAD binding "GO:0006351//transcription, DNA-templated;GO:0007183//SMAD protein complex assembly;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006470//protein dephosphorylation" "gi|148704578|gb|EDL36525.1|/0/protein phosphatase 1A, magnesium dependent, alpha isoform, isoform CRA_c, partial [Mus musculus]" 14154 6834 70.45 70.13666667 -0.00643084 Down 0.101132047 Fem1a feminization 1 homolog a (C. elegans) K10349|1|6e-96|356|tru:101062979|Fem-1 homolog b GO:0044424 GO:0031862 GO:0006954//inflammatory response;GO:0031396//regulation of protein ubiquitination;GO:0043405//regulation of MAP kinase activity gi|74199401|dbj|BAE33219.1|/0/unnamed protein product [Mus musculus] 69702 1451 31.66 31.97333333 0.014207903 Up 0.101132047 Ndufaf1 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1" K18159|1|0.0|674|mmu:69702|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1 GO:0043231//intracellular membrane-bounded organelle GO:0050136//NADH dehydrogenase (quinone) activity GO:0044710 "gi|31980802|ref|NP_081451.3|/0/complex I intermediate-associated protein 30, mitochondrial [Mus musculus] " 383619 2541 1.523333333 1.566666667 0.040466592 Up 0.101085035 Aim2 absent in melanoma 2 K12966|1|8e-179|630|mmu:383619|absent in melanoma 2 GO:0043231//intracellular membrane-bounded organelle;GO:0005737//cytoplasm;GO:0043234//protein complex GO:0005515//protein binding;GO:0043566//structure-specific DNA binding GO:0002253//activation of immune response;GO:0012501//programmed cell death;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0050691//regulation of defense response to virus by host;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0019221//cytokine-mediated signaling pathway;GO:0032731//positive regulation of interleukin-1 beta production;GO:0031334//positive regulation of protein complex assembly;GO:0042493//response to drug;GO:0010950//positive regulation of endopeptidase activity;GO:0035456//response to interferon-beta gi|162461985|ref|NP_001013801.2|/6.52948e-178/interferon-inducible protein AIM2 [Mus musculus] 241915 10925 1.373333333 1.416666667 0.044818504 Up 0.101085035 Phc3 polyhomeotic-like 3 (Drosophila) K11458|1|0.0|1119|mmu:241915|polyhomeotic-like protein 3 GO:0031519//PcG protein complex;GO:0031519//PcG protein complex;GO:0031519//PcG protein complex;GO:0031519//PcG protein complex GO:0005488//binding;GO:0005488//binding;GO:0005488//binding;GO:0005488//binding - gi|260099711|ref|NP_001159426.1|/0/polyhomeotic-like protein 3 isoform 1 [Mus musculus] 227195 13491.41 1.496666667 1.536666667 0.038051306 Up 0.101085035 Ino80d INO80 complex subunit D K11668|1|0.0|1598|rno:316440|INO80 complex subunit D GO:0043231//intracellular membrane-bounded organelle - "GO:0006259//DNA metabolic process;GO:0006351//transcription, DNA-templated" gi|167830449|ref|NP_001108081.1|/0/INO80 complex subunit D isoform 1 [Mus musculus] 67689 1915 1.506666667 1.463333333 -0.042101833 Down 0.101085035 Aldh3b1 "aldehyde dehydrogenase 3 family, member B1" K00129|1|0.0|937|mmu:67689|aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5] GO:0044444//cytoplasmic part "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor" GO:0006979//response to oxidative stress;GO:0006067//ethanol metabolic process;GO:0006081//cellular aldehyde metabolic process gi|34328288|ref|NP_080592.2|/0/aldehyde dehydrogenase family 3 member B1 [Mus musculus] 20855 3743 1.363333333 1.326666667 -0.039332412 Down 0.101085035 Stc1 stanniocalcin 1 - GO:0044459;GO:0044424;GO:0044421 GO:0005102//receptor binding GO:0001666//response to hypoxia;GO:0030002//cellular anion homeostasis;GO:0031667//response to nutrient levels;GO:0001893//maternal placenta development;GO:0006875//cellular metal ion homeostasis;GO:0051384//response to glucocorticoid;GO:0007165//signal transduction;GO:0051591//response to cAMP gi|134053908|ref|NP_033311.3|/4.33867e-128/stanniocalcin-1 precursor [Mus musculus] 244238 3777 1.256666667 1.22 -0.042720875 Down 0.101085035 Mrgpre "MAS-related GPR, member E" K08393|1|3e-141|505|mmu:244238|Mas-related G protein-coupled receptor member E GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|30425312|ref|NP_780743.1|/2.9259e-140/mas-related G-protein coupled receptor member E [Mus musculus] 216345 6956 1.213333333 1.176666667 -0.044270267 Down 0.101085035 Zfc3h1 "zinc finger, C3H1-type containing" - - - - gi|90991706|ref|NP_001028433.2|/0/zinc finger C3H1 domain-containing protein [Mus musculus] 74753 1558 1.363333333 1.326666667 -0.039332412 Down 0.101085035 Trmo tRNA methyltransferase O K01669|1|7e-11|71.2|dme:Dmel_CG18853|deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] - GO:0003824//catalytic activity - gi|110626025|ref|NP_083362.1|/0/tRNA (adenine(37)-N6)-methyltransferase [Mus musculus] 94227 6946 1.476666667 1.44 -0.036275386 Down 0.101085035 Pi15 peptidase inhibitor 15 K19919|1|2e-78|298|gga:415818|cysteine-rich secretory protein - GO:0004857//enzyme inhibitor activity GO:0051346//negative regulation of hydrolase activity gi|225690632|ref|NP_444421.2|/6.62544e-157/peptidase inhibitor 15 precursor [Mus musculus] 80978 1809 1.786666667 1.743333333 -0.035422054 Down 0.101085035 Mrgprh "MAS-related GPR, member H" K04303|1|2e-79|299|shr:100926668|MAS1 oncogene GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|13507682|ref|NP_109651.1|/1.53309e-167/mas-related G-protein coupled receptor member H [Mus musculus] 102466781 70 1.436666667 1.4 -0.037298541 Down 0.101085035 Mir6991 microRNA 6991 - - - - - 74044 4555 1.16 1.196666667 0.044896538 Up 0.101085035 Ttf2 "transcription termination factor, RNA polymerase II" K15173|1|0.0|2063|mmu:74044|transcription termination factor 2 [EC:3.6.4.-] GO:0043231//intracellular membrane-bounded organelle;GO:0030529//intracellular ribonucleoprotein complex "GO:0032550;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042623//ATPase activity, coupled" "GO:0006396//RNA processing;GO:0006351//transcription, DNA-templated" gi|254692909|ref|NP_001013044.2|/0/transcription termination factor 2 [Mus musculus] 14107 14627 1.386666667 1.346666667 -0.042228235 Down 0.101085035 Fat1 FAT atypical cadherin 1 K16506|1|0.0|8879|mmu:14107|protocadherin Fat 1/2/3 - - - - 67072 4451.03 31.5 31.79666667 0.013523703 Up 0.101038023 Cdc37l1 cell division cycle 37-like 1 K09554|1|2e-54|218|fch:102058416|cell division cycle protein 37;K11219|5|1e-53|215|apla:101795689|non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2] GO:0044424;GO:0044424;GO:0044424;GO:0044424 - - "gi|148709720|gb|EDL41666.1|/2.49107e-164/cell division cycle 37 homolog (S. cerevisiae)-like 1, isoform CRA_c, partial [Mus musculus]" 83701 3030.52 30.91333333 31.21666667 0.014087268 Up 0.101038023 Srrt serrate RNA effector molecule homolog (Arabidopsis) K07378|1|6e-14|82.8|fch:102045900|neuroligin GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0005488//binding;GO:0005488//binding;GO:0005488//binding "GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0019827//stem cell population maintenance;GO:0006351//transcription, DNA-templated;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0019827//stem cell population maintenance;GO:0006351//transcription, DNA-templated;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0019827//stem cell population maintenance;GO:0006351//transcription, DNA-templated" gi|158186670|ref|NP_001103379.1|/0/serrate RNA effector molecule homolog isoform 2 [Mus musculus] 69077 1743 52.7 52.99333333 0.008007915 Up 0.100934597 Psmd11 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 11" K03036|1|0.0|778|mmu:69077|26S proteasome regulatory subunit N6 GO:0031981//nuclear lumen;GO:0000502//proteasome complex;GO:0044444//cytoplasmic part - "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0006915//apoptotic process;GO:0044764;GO:0051320;GO:0016070//RNA metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0030154//cell differentiation;GO:0043623//cellular protein complex assembly;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|564373438|ref|XP_006247049.1|/0/PREDICTED: 26S proteasome non-ATPase regulatory subunit 11 isoform X1 [Rattus norvegicus] 245688 2272 59.23666667 59.51333333 0.006722465 Up 0.100812366 Rbbp7 retinoblastoma binding protein 7 K11659|1|0.0|892|mmu:245688|histone-binding protein RBBP7 GO:0000118//histone deacetylase complex;GO:0031519//PcG protein complex GO:0005488//binding GO:0010286//heat acclimation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006259//DNA metabolic process;GO:0016049//cell growth;GO:0043486//histone exchange;GO:0032502//developmental process gi|157909799|ref|NP_033057.3|/0/histone-binding protein RBBP7 [Mus musculus] 21846 3883 57.45333333 57.17 -0.007132307 Down 0.100812366 Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 K05120|1|0.0|2272|mmu:21846|tyrosine kinase receptor 1 [EC:2.7.10.1] GO:0031224//intrinsic component of membrane GO:0032550;GO:0004713//protein tyrosine kinase activity GO:0033993//response to lipid;GO:0016477//cell migration;GO:0001525//angiogenesis;GO:0043009//chordate embryonic development;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007154//cell communication gi|144446133|ref|NP_035717.2|/0/tyrosine-protein kinase receptor Tie-1 precursor [Mus musculus] 22225 3215.03 37.76666667 37.48666667 -0.010735909 Down 0.100812366 Usp5 ubiquitin specific peptidase 5 (isopeptidase T) K11836|1|0.0|1644|mmu:22225|ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12] - - - - 11975 4001.55 46.86333333 46.58666667 -0.008542468 Down 0.100812366 Atp6v0a1 "ATPase, H+ transporting, lysosomal V0 subunit A1" K02154|1|0.0|1623|rno:29757|V-type H+-transporting ATPase subunit a GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0033176//proton-transporting V-type ATPase complex;GO:0012506//vesicle membrane;GO:0048770 GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0019899//enzyme binding "GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient" gi|12025532|ref|NP_058616.1|/0/V-type proton ATPase 116 kDa subunit a isoform 1 isoform 1 [Mus musculus] 71472 4725.59 38.92333333 38.64666667 -0.010291281 Down 0.100812366 Usp19 ubiquitin specific peptidase 19 K11847|1|0.0|2434|mmu:71472|ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12] - - - - 56692 1263 44.42 44.7 0.009065439 Up 0.100812366 Lamtor3 "late endosomal/lysosomal adaptor, MAPK and MTOR activator 3" K04370|1|2e-61|239|mmu:56692|ragulator complex protein LAMTOR3 GO:0031902//late endosome membrane GO:0008047//enzyme activator activity;GO:0030695//GTPase regulator activity;GO:0005515//protein binding GO:0009967//positive regulation of signal transduction;GO:0043200//response to amino acid;GO:0008104//protein localization gi|9910452|ref|NP_064304.1|/1.30407e-60/ragulator complex protein LAMTOR3 [Mus musculus] 208151 7964 0.01 0.02 1 Up 0.100784159 Tmem132b transmembrane protein 132B K17599|1|0.0|2066|mmu:208151|transmembrane protein 132 - - - gi|298493223|ref|NP_001177281.1|/0/transmembrane protein 132B precursor [Mus musculus] 74129 2979 0.01 0.023333333 1.222392421 Up 0.100784159 Dmgdh dimethylglycine dehydrogenase precursor K00315|1|0.0|1731|mmu:74129|dimethylglycine dehydrogenase [EC:1.5.8.4] GO:0043231//intracellular membrane-bounded organelle GO:0019842//vitamin binding;GO:0046997;GO:0000166//nucleotide binding;GO:0008168//methyltransferase activity GO:0006544//glycine metabolic process;GO:0019695//choline metabolic process;GO:0006577//amino-acid betaine metabolic process "gi|21311901|ref|NP_083048.1|/0/dimethylglycine dehydrogenase, mitochondrial precursor [Mus musculus]" 100043213 3449 0.01 0.02 1 Up 0.100784159 5330434G04Rik RIKEN cDNA 5330434G04 gene - - - - - 27219 3068 0.023333333 0.01 -1.222392421 Down 0.100784159 Sgk2 serum/glucocorticoid regulated kinase 2 K13303|1|2e-176|622|mmu:27219|serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1] - - - - 227157 2422 0.01 0.023333333 1.222392421 Up 0.100784159 Mpp4 "membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)" K06091|1|3e-80|302|crg:105335272|MAGUK p55 subfamily member 5 GO:0044424;GO:0097060//synaptic membrane;GO:0044424;GO:0097060//synaptic membrane - GO:0008104//protein localization;GO:0008104//protein localization gi|258547158|ref|NP_001158154.1|/0/MAGUK p55 subfamily member 4 isoform 1 [Mus musculus] 11687 2414 0.01 0.023333333 1.222392421 Up 0.100784159 Alox15 arachidonate 15-lipoxygenase K00460|1|0.0|1296|mmu:11687|arachidonate 15-lipoxygenase [EC:1.13.11.33] GO:0031981//nuclear lumen;GO:0005886//plasma membrane;GO:0044444//cytoplasmic part "GO:0046914//transition metal ion binding;GO:0008200//ion channel inhibitor activity;GO:0016853//isomerase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0016803" GO:0006636//unsaturated fatty acid biosynthetic process;GO:0006884//cell volume homeostasis;GO:0001676//long-chain fatty acid metabolic process;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0001503//ossification;GO:0006690//icosanoid metabolic process;GO:0022409//positive regulation of cell-cell adhesion;GO:0016049//cell growth;GO:0006873//cellular ion homeostasis;GO:0006952//defense response gi|568971264|ref|XP_006532099.1|/0/PREDICTED: arachidonate 15-lipoxygenase isoform X1 [Mus musculus] 16512 3583 0.02 0.01 -1 Down 0.100784159 Kcnh3 "potassium voltage-gated channel, subfamily H (eag-related), member 3" K04906|1|0.0|1863|mmu:16512|potassium voltage-gated channel Eag-related subfamily H member 3 GO:0031224//intrinsic component of membrane GO:0060089;GO:0005267//potassium channel activity "GO:0007165//signal transduction;GO:0006351//transcription, DNA-templated;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport" gi|168693667|ref|NP_034731.3|/0/potassium voltage-gated channel subfamily H member 3 [Mus musculus] 272790 2338 0.01 0.023333333 1.222392421 Up 0.100784159 Magee2 "melanoma antigen, family E, 2" K12464|1|1e-31|140|ecb:100147318|melanoma-associated antigen D1 - - - - 627984 3457 0.02 0.01 -1 Down 0.100784159 Nlrp1c-ps "NLR family, pyrin domain containing 1C, pseudogene" "K12798|1|0.0|1613|mmu:195046|NACHT, LRR and PYD domains-containing protein 1" - - - - 14126 2429 0.01 0.023333333 1.222392421 Up 0.100784159 Ms4a2 "membrane-spanning 4-domains, subfamily A, member 2" "K08090|1|3e-92|342|mmu:14126|membrane-spanning 4-domains, subfamily A, member 2" GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0032997;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0032997;GO:0016021//integral component of membrane;GO:0044459;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0032997 GO:0019904//protein domain specific binding;GO:0019763//immunoglobulin receptor activity;GO:0019865//immunoglobulin binding;GO:0019900//kinase binding;GO:0019904//protein domain specific binding;GO:0019763//immunoglobulin receptor activity;GO:0019865//immunoglobulin binding;GO:0019900//kinase binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0019763//immunoglobulin receptor activity;GO:0019865//immunoglobulin binding;GO:0019900//kinase binding GO:0007186//G-protein coupled receptor signaling pathway;GO:0010863//positive regulation of phospholipase C activity;GO:0001816//cytokine production;GO:0010522//regulation of calcium ion transport into cytosol;GO:0006952//defense response;GO:0033008;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010863//positive regulation of phospholipase C activity;GO:0001816//cytokine production;GO:0010522//regulation of calcium ion transport into cytosol;GO:0006952//defense response;GO:0033008;GO:0051649//establishment of localization in cell;GO:0044765//single-organism transport;GO:0007165//signal transduction;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010863//positive regulation of phospholipase C activity;GO:0001816//cytokine production;GO:0010522//regulation of calcium ion transport into cytosol;GO:0006952//defense response;GO:0033008 gi|444741652|ref|NP_001263258.1|/2.27126e-63/high affinity immunoglobulin epsilon receptor subunit beta isoform c [Mus musculus] 239739 3343 0.02 0.01 -1 Down 0.100784159 Lamp3 lysosomal-associated membrane protein 3 K06562|1|0.0|735|mmu:239739|lysosomal-associated membrane protein 3;K05864|3|1e-157|263|mmu:67738|peptidyl-prolyl isomerase D [EC:5.2.1.8] GO:0031981//nuclear lumen;GO:0005764//lysosome;GO:0031224//intrinsic component of membrane;GO:0005856//cytoskeleton;GO:0097232//lamellar body membrane GO:0033218//amide binding;GO:0005527//macrolide binding;GO:0031072//heat shock protein binding;GO:0035258//steroid hormone receptor binding;GO:0016859//cis-trans isomerase activity GO:0006457//protein folding;GO:0018208//peptidyl-proline modification;GO:0006366//transcription from RNA polymerase II promoter;GO:0009306//protein secretion;GO:0019079//viral genome replication;GO:0006915//apoptotic process;GO:0006996//organelle organization;GO:0065003;GO:0034644//cellular response to UV;GO:0006950//response to stress;GO:0042391//regulation of membrane potential gi|118601015|ref|NP_796330.2|/0/lysosome-associated membrane glycoprotein 3 precursor [Mus musculus] 100101919 12282 0.01 0.02 1 Up 0.100784159 Dnah7c "dynein, axonemal, heavy chain 7C" "K10408|1|0.0|7772|mmu:100101919|dynein heavy chain, axonemal" - - - "gi|878293351|ref|NP_001297264.1|/0/dynein, axonemal, heavy chain 7C [Mus musculus]" 74004 5987 0.026666667 0.013333333 -1 Down 0.100784159 Jakmip3 janus kinase and microtubule interacting protein 3 K20478|1|6e-74|283|sko:100376626|golgin subfamily B member 1;K10388|3|1e-11|75.9|hgl:101703656|plectin;K11499|4|5e-10|70.9|tup:102487040|centromere protein F;K10352|5|8e-10|70.1|aag:AaeL_AAEL001411|myosin heavy chain - GO:0019899//enzyme binding - gi|60360524|dbj|BAD90506.1|/0/mKIAA4091 protein [Mus musculus] 225631 13407 0.023333333 0.01 -1.222392421 Down 0.100784159 Onecut2 "one cut domain, family member 2" "K08026|1|3e-131|474|cjo:107325678|one cut domain, family member 1, hepatocyte nuclear factor 6" GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0048666//neuron development;GO:0031016//pancreas development;GO:0007160//cell-matrix adhesion;GO:0006366//transcription from RNA polymerase II promoter;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0030855//epithelial cell differentiation;GO:0010927;GO:0016477//cell migration gi|119220568|ref|NP_919244.2|/0/one cut domain family member 2 [Mus musculus] 70893 2465 0.01 0.023333333 1.222392421 Up 0.100784159 Glb1l3 "galactosidase, beta 1 like 3" K12309|1|1e-101|373|chx:102178493|beta-galactosidase [EC:3.2.1.23] - GO:0015925//galactosidase activity GO:0044238//primary metabolic process "gi|148693363|gb|EDL25310.1|/0/mCG125130, isoform CRA_b, partial [Mus musculus]" 74020 3670 0.01 0.02 1 Up 0.100784159 Cpne4 copine IV K06491|1|3e-08|63.9|cin:100183448|neural cell adhesion molecule;K19663|2|6e-07|59.7|xtr:100496779|classical protein kinase C gamma type [EC:2.7.11.13] - - - "gi|148689145|gb|EDL21092.1|/0/copine IV, isoform CRA_a, partial [Mus musculus]" 320747 2943 0.01 0.023333333 1.222392421 Up 0.100784159 Lingo4 leucine rich repeat and Ig domain containing 4 K16360|1|2e-33|147|mgp:100539692|netrin-G3 ligand;K13023|3|6e-32|142|bfo:BRAFLDRAFT_89744|carboxypeptidase N regulatory subunit;K16351|4|1e-31|141|sko:100378039|netrin-G2 ligand GO:0031224//intrinsic component of membrane - - gi|29789433|ref|NP_796224.1|/0/leucine-rich repeat and immunoglobulin-like domain containing-NOGO receptor-interacting protein 4 [Mus musculus] 58205 3415 0.02 0.01 -1 Down 0.100784159 Pdcd1lg2 programmed cell death 1 ligand 2 K06708|1|8e-131|471|mmu:58205|programmed cell death 1 ligand 2 GO:0031224//intrinsic component of membrane - GO:0042098//T cell proliferation "gi|148709736|gb|EDL41682.1|/5.80382e-140/programmed cell death 1 ligand 2, isoform CRA_a, partial [Mus musculus]" 227327 2608 0.01 0.023333333 1.222392421 Up 0.100784159 B3gnt7 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7" "K09664|1|0.0|803|mmu:227327|beta-1,3-N-acetylglucosaminyltransferase 7 [EC:2.4.1.-]" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system "GO:0016758//transferase activity, transferring hexosyl groups;GO:0008194//UDP-glycosyltransferase activity" GO:0006024//glycosaminoglycan biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0006493//protein O-linked glycosylation "gi|227496327|ref|NP_660257.2|/0/UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 [Mus musculus]" 258019 2672 0.023333333 0.01 -1.222392421 Down 0.100784159 Olfr212 olfactory receptor 212 K04257|1|0.0|650|mmu:258019|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007154//cell communication gi|58801366|ref|NP_001011800.1|/0/olfactory receptor 212 [Mus musculus] 100039691 3337 0.02 0.01 -1 Down 0.100784159 Lncenc1 "long non-coding RNA, embryonic stem cells expressed 1" K09228|1|3e-10|70.5|pbi:103063693|KRAB domain-containing zinc finger protein - - - gi|156392445|ref|XP_001636059.1|/3.62233e-17/predicted protein [Nematostella vectensis] 14804 3024 0.01 0.02 1 Up 0.100784159 Grid2 "glutamate receptor, ionotropic, delta 2" K05207|1|0.0|1976|mmu:14804|glutamate receptor delta-2 subunit GO:0030313//cell envelope;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0005887//integral component of plasma membrane GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0019904//protein domain specific binding GO:0001964//startle response;GO:0007270//neuron-neuron synaptic transmission;GO:0042981//regulation of apoptotic process;GO:0031175//neuron projection development;GO:0051899//membrane depolarization;GO:0008104//protein localization;GO:0044765//single-organism transport;GO:0007215//glutamate receptor signaling pathway "gi|6680091|ref|NP_032193.1|/0/glutamate receptor ionotropic, delta-2 precursor [Mus musculus]" 408191 3748 0.01 0.02 1 Up 0.100784159 Gm5415 predicted gene 5415 K03345|1|0.0|938|mmu:408191|sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68] - GO:0016787//hydrolase activity GO:0006915//apoptotic process;GO:0019538//protein metabolic process gi|256017236|ref|NP_001157758.1|/0/sentrin 14 [Mus musculus] 18013 3137 0.023333333 0.01 -1.222392421 Down 0.100784159 Neurod2 neurogenic differentiation 2 K09078|1|9e-172|607|mmu:18013|neurogenic differentiation factor 2 GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0046983//protein dimerization activity;GO:0044212//transcription regulatory region DNA binding "GO:0006351//transcription, DNA-templated;GO:0051094//positive regulation of developmental process;GO:0051602//response to electrical stimulus;GO:0051093//negative regulation of developmental process;GO:0007612//learning;GO:0051592//response to calcium ion;GO:0048167//regulation of synaptic plasticity;GO:0021549//cerebellum development;GO:0044093;GO:0032446//protein modification by small protein conjugation;GO:0019722//calcium-mediated signaling;GO:0030182//neuron differentiation" gi|3309511|gb|AAC26057.1|/7.55551e-171/NeuroD2 [Mus musculus] 211924 4088 0.02 0.01 -1 Down 0.100784159 Dsg1c desmoglein 1 gamma K07596|1|0.0|1712|mmu:211924|desmoglein 1 - - - - 66722 3589 0.02 0.01 -1 Down 0.100784159 Spag16 sperm associated antigen 16 K19760|1|9e-37|157|tad:TRIADDRAFT_49686|dynein assembly factor with WDR repeat domains 1 - - - - 60505 3090 0.01 0.023333333 1.222392421 Up 0.100784159 Il21 interleukin 21 K05434|1|9e-71|271|mmu:60505|interleukin 21 GO:0044421;GO:0044421 GO:0005126//cytokine receptor binding;GO:0005126//cytokine receptor binding GO:0030183//B cell differentiation;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0002370;GO:0042095//interferon-gamma biosynthetic process;GO:0030888//regulation of B cell proliferation;GO:0021700//developmental maturation;GO:0001819//positive regulation of cytokine production;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0001779//natural killer cell differentiation;GO:0042098//T cell proliferation;GO:0030183//B cell differentiation;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0002370;GO:0042095//interferon-gamma biosynthetic process;GO:0030888//regulation of B cell proliferation;GO:0021700//developmental maturation;GO:0001819//positive regulation of cytokine production;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0001779//natural killer cell differentiation;GO:0042098//T cell proliferation gi|11140821|ref|NP_068554.1|/7.38966e-70/interleukin-21 isoform 2 precursor [Mus musculus] 54483 3094 0.01 0.023333333 1.222392421 Up 0.100784159 Mefv Mediterranean fever K12803|1|0.0|1491|mmu:54483|pyrin GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding GO:0010950//positive regulation of endopeptidase activity;GO:0032682//negative regulation of chemokine production;GO:0006954//inflammatory response;GO:0032611//interleukin-1 beta production;GO:0010950//positive regulation of endopeptidase activity;GO:0032682//negative regulation of chemokine production;GO:0006954//inflammatory response;GO:0032611//interleukin-1 beta production;GO:0010950//positive regulation of endopeptidase activity;GO:0032682//negative regulation of chemokine production;GO:0006954//inflammatory response;GO:0032611//interleukin-1 beta production gi|241666417|ref|NP_062326.2|/0/pyrin isoform 3 [Mus musculus] 214111 5244 0.023333333 0.01 -1.222392421 Down 0.100784159 Slc24a1 "solute carrier family 24 (sodium/potassium/calcium exchanger), member 1" "K13749|1|0.0|1359|mmu:214111|solute carrier family 24 (sodium/potassium/calcium exchanger), member 1" GO:0031224//intrinsic component of membrane GO:0015081//sodium ion transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0006816//calcium ion transport "gi|148694126|gb|EDL26073.1|/0/solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 [Mus musculus]" 574403 5371 0.01 0.023333333 1.222392421 Up 0.100784159 Fam196b "family with sequence similarity 196, member B" - - - - - 20445 2396 0.01 0.023333333 1.222392421 Up 0.100784159 St6galnac1 "ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1" "K03479|1|0.0|1005|mmu:20445|alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7A) [EC:2.4.99.3]" GO:0031228//intrinsic component of Golgi membrane GO:0008373//sialyltransferase activity GO:0006464//cellular protein modification process;GO:0009311//oligosaccharide metabolic process "gi|126116572|ref|NP_035501.2|/0/alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 [Mus musculus]" 100042437 921 0.023333333 0.01 -1.222392421 Down 0.100784159 Vmn1r79 vomeronasal 1 receptor 79 K04614|1|1e-176|620|mmu:100042437|vomeronasal1 receptor GO:0016021//integral component of membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0010033//response to organic substance gi|295424084|ref|NP_001160307.1|/9.72142e-176/vomeronasal 1 receptor 79 [Mus musculus] 272031 3762 0.01 0.02 1 Up 0.100784159 Plppr1 phospholipid phosphatase related 1 K19581|1|0.0|657|mmu:272031|lipid phosphate phosphatase-related protein type 1/2/5 GO:0031224//intrinsic component of membrane - GO:0048731//system development gi|60360644|dbj|BAD90332.1|/0/mKIAA4247 protein [Mus musculus] 70882 2956 0.023333333 0.01 -1.222392421 Down 0.100784159 Armc3 armadillo repeat containing 3 K08332|1|8e-09|65.5|aam:106497924|vacuolar protein 8;K15043|3|7e-08|62.4|mze:101480423|importin subunit alpha-2 - - - gi|409168302|ref|NP_001258492.1|/0/armadillo repeat-containing protein 3 isoform 2 [Mus musculus] 83770 3060 0.023333333 0.01 -1.222392421 Down 0.100784159 Tas1r2 "taste receptor, type 1, member 2" K04625|1|0.0|1682|mmu:83770|taste receptor type 1 member 2 GO:0031224//intrinsic component of membrane GO:0004930//G-protein coupled receptor activity;GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0050909//sensory perception of taste gi|13994203|ref|NP_114079.1|/0/taste receptor type 1 member 2 precursor [Mus musculus] 210719 3201 0.023333333 0.01 -1.222392421 Down 0.100784159 Mkx mohawk homeobox K19383|1|7e-09|65.9|lve:103089964|homeobox protein TGIF1;K19553|4|4e-08|63.5|crg:105320634|homeobox protein TGIF2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0003677//DNA binding;GO:0003700//transcription factor activity, sequence-specific DNA binding;GO:0008134//transcription factor binding" "GO:0035989//tendon development;GO:0006351//transcription, DNA-templated;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0030198//extracellular matrix organization;GO:0045445//myoblast differentiation;GO:0048646//anatomical structure formation involved in morphogenesis" "gi|148691080|gb|EDL23027.1|/0/mohawk, partial [Mus musculus]" 12738 3079 0.01 0.023333333 1.222392421 Up 0.100784159 Cldn2 claudin 2 K06087|1|7e-105|384|mmu:12738|claudin GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex GO:0005515//protein binding GO:0016337//single organismal cell-cell adhesion gi|7710004|ref|NP_057884.1|/5.96879e-104/claudin-2 [Mus musculus] 319818 3354 0.02 0.01 -1 Down 0.100784159 A930011G23Rik RIKEN cDNA A930011G23 gene - - - - "gi|148688369|gb|EDL20316.1|/2.13505e-78/mCG144685, partial [Mus musculus]" 26946 3547.04 0.02 0.01 -1 Down 0.100784159 Trpc7 "transient receptor potential cation channel, subfamily C, member 7" K04970|1|0.0|1614|mcc:712863|transient receptor potential cation channel subfamily C member 7 GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0005261//cation channel activity;GO:0005261//cation channel activity;GO:0005261//cation channel activity GO:0044763;GO:0006816//calcium ion transport;GO:0000041//transition metal ion transport;GO:0044763;GO:0006816//calcium ion transport;GO:0000041//transition metal ion transport;GO:0044763;GO:0006816//calcium ion transport;GO:0000041//transition metal ion transport gi|966948818|ref|XP_014996393.1|/0/PREDICTED: short transient receptor potential channel 7 [Macaca mulatta] 74403 3611 0.01 0.02 1 Up 0.100784159 4933400F21Rik RIKEN cDNA 4933400F21 gene - - - - - 15569 3741 0.02 0.01 -1 Down 0.100784159 Elavl2 "ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)" K13208|1|0.0|731|rno:286973|ELAV like protein 2/3/4 - GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding - gi|46592818|ref|NP_997568.1|/0/ELAV-like protein 2 isoform 1 [Mus musculus] 22671 3029 0.01 0.023333333 1.222392421 Up 0.100784159 Rnf112 ring finger protein 112 K17339|1|1e-15|88.6|lcm:102345442|atlastin [EC:3.6.5.-] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 - gi|20127402|ref|NP_033574.2|/0/RING finger protein 112 isoform 1 [Mus musculus] 71753 3206 0.023333333 0.01 -1.222392421 Down 0.100784159 Tmprss6 transmembrane serine protease 6 K09637|1|0.0|1571|mmu:71753|transmembrane protease serine 6 [EC:3.4.21.-] GO:0031224//intrinsic component of membrane GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0030195//negative regulation of blood coagulation;GO:0055080//cation homeostasis gi|125656152|ref|NP_082178.2|/0/transmembrane protease serine 6 [Mus musculus] 18171 2417 0.01 0.023333333 1.222392421 Up 0.100784159 Nr1i2 "nuclear receptor subfamily 1, group I, member 2" K08540|1|0.0|880|mmu:18171|pregnane X receptor GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003677//DNA binding" "GO:0006351//transcription, DNA-templated;GO:0015893//drug transport;GO:0009755//hormone-mediated signaling pathway;GO:0006351//transcription, DNA-templated;GO:0015893//drug transport;GO:0009755//hormone-mediated signaling pathway" gi|148536879|ref|NP_001091874.1|/0/nuclear receptor subfamily 1 group I member 2 isoform 2 [Mus musculus] 244859 2686 0.01 0.023333333 1.222392421 Up 0.100784159 Ankk1 ankyrin repeat and kinase domain containing 1 K16289|1|0.0|1513|mmu:244859|ankyrin repeat and protein kinase domain-containing protein 1 [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|27370420|ref|NP_766510.1|/0/ankyrin repeat and protein kinase domain-containing protein 1 [Mus musculus] 67470 3048 0.01 0.023333333 1.222392421 Up 0.100784159 Abcg8 "ATP-binding cassette, sub-family G (WHITE), member 8" "K05684|1|0.0|1241|mmu:67470|ATP-binding cassette, subfamily G (WHITE), member 8 (sterolin 2)" GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex;GO:0044459 GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0015248//sterol transporter activity;GO:0046983//protein dimerization activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0015248//sterol transporter activity;GO:0046983//protein dimerization activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0015248//sterol transporter activity;GO:0046983//protein dimerization activity GO:0042221//response to chemical;GO:0030299//intestinal cholesterol absorption;GO:0032372;GO:0009154//purine ribonucleotide catabolic process;GO:0055092//sterol homeostasis;GO:0031667//response to nutrient levels;GO:0042221//response to chemical;GO:0030299//intestinal cholesterol absorption;GO:0032372;GO:0009154//purine ribonucleotide catabolic process;GO:0055092//sterol homeostasis;GO:0031667//response to nutrient levels;GO:0042221//response to chemical;GO:0030299//intestinal cholesterol absorption;GO:0032372;GO:0009154//purine ribonucleotide catabolic process;GO:0055092//sterol homeostasis;GO:0031667//response to nutrient levels gi|31322262|gb|AAO45096.1|/0/ATP-binding cassette sub-family G member 8 [Mus musculus] 18383 2818 0.023333333 0.01 -1.222392421 Down 0.100784159 Tnfrsf11b "tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)" K05148|1|0.0|819|mmu:18383|tumor necrosis factor receptor superfamily member 11B GO:0031012//extracellular matrix;GO:0044421 GO:0005102//receptor binding GO:0012501//programmed cell death;GO:0043062//extracellular structure organization;GO:0010038//response to metal ion;GO:0042475//odontogenesis of dentin-containing tooth;GO:0048545//response to steroid hormone;GO:0031667//response to nutrient levels;GO:0007154//cell communication;GO:0032845 gi|113930716|ref|NP_032790.3|/0/tumor necrosis factor receptor superfamily member 11B precursor [Mus musculus] 78390 3311 0.01 0.02 1 Up 0.100784159 Pla2g4d "phospholipase A2, group IVD" K16342|1|0.0|1621|mmu:78390|cytosolic phospholipase A2 [EC:3.1.1.4] GO:0031982//vesicle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0043169//cation binding;GO:0004620//phospholipase activity GO:0046488//phosphatidylinositol metabolic process;GO:0046470//phosphatidylcholine metabolic process;GO:0006658//phosphatidylserine metabolic process;GO:0046473//phosphatidic acid metabolic process;GO:0046471//phosphatidylglycerol metabolic process gi|67906183|ref|NP_001019308.1|/0/cytosolic phospholipase A2 delta [Mus musculus] 270120 18468 0.013333333 0.026666667 1 Up 0.100784159 Fat3 FAT atypical cadherin 3 K16506|1|0.0|8779|mmu:270120|protocadherin Fat 1/2/3 - - - - 213527 2414 0.01 0.023333333 1.222392421 Up 0.100784159 Pth2r parathyroid hormone 2 receptor K04586|1|0.0|1077|mmu:213527|parathyroid hormone receptor 2 GO:0031224//intrinsic component of membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway gi|29293832|ref|NP_644676.1|/0/parathyroid hormone 2 receptor precursor [Mus musculus] 21752 3426 0.01 0.02 1 Up 0.100784159 Tert telomerase reverse transcriptase K11126|1|0.0|2174|mmu:21752|telomerase reverse transcriptase [EC:2.7.7.49] GO:0016604//nuclear body;GO:0043232;GO:0030529//intracellular ribonucleoprotein complex GO:0043169//cation binding;GO:0003723//RNA binding;GO:0003720//telomerase activity;GO:0042802//identical protein binding GO:0006278//RNA-dependent DNA biosynthetic process;GO:0006915//apoptotic process;GO:0007569//cell aging gi|6678291|ref|NP_033380.1|/0/telomerase reverse transcriptase [Mus musculus] 237553 5722 0.023333333 0.01 -1.222392421 Down 0.100784159 Trhde TRH-degrading enzyme K01306|1|0.0|2021|mmu:237553|pyroglutamyl-peptidase II [EC:3.4.19.6] GO:0031224//intrinsic component of membrane "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process "gi|148689814|gb|EDL21761.1|/0/TRH-degrading enzyme, isoform CRA_b [Mus musculus]" 140477 4054 0.02 0.01 -1 Down 0.100784159 Dmbx1 diencephalon/mesencephalon homeobox 1 K01530|1|3e-24|117|cmy:102942998|phospholipid-translocating ATPase [EC:3.6.3.1];K04138|2|1e-22|112|bfo:BRAFLDRAFT_68140|adrenergic receptor alpha-2A;K09324|3|1e-16|92.0|bfo:BRAFLDRAFT_116854|homeobox protein goosecoid;K09329|4|3e-16|90.9|bfo:BRAFLDRAFT_204029|paired mesoderm homeobox protein;K09336|5|4e-16|90.5|cjo:107315150|visual system homeobox protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity "GO:0007626//locomotory behavior;GO:0006351//transcription, DNA-templated;GO:0007631//feeding behavior;GO:0007626//locomotory behavior;GO:0006351//transcription, DNA-templated;GO:0007631//feeding behavior" gi|21623544|dbj|BAC00919.1|/3.59312e-144/PaxB [Mus musculus] 72258 7022 0.02 0.01 -1 Down 0.100784159 Kcnk10 "potassium channel, subfamily K, member 10" K04920|1|0.0|846|mmu:72258|potassium channel subfamily K member 10 - - - - 212516 2551 0.01 0.023333333 1.222392421 Up 0.100784159 Efcab12 EF-hand calcium binding domain 12 K02912|1|3e-78|296|shr:100915837|large subunit ribosomal protein L32e - GO:0046872//metal ion binding - gi|160333243|ref|NP_001103976.1|/0/EF-hand calcium-binding domain-containing protein 12 [Mus musculus] 270028 3142 0.023333333 0.01 -1.222392421 Down 0.100784159 Fam155a "family with sequence similarity 155, member A" - GO:0031224//intrinsic component of membrane - - gi|27734096|ref|NP_775622.1|/0/transmembrane protein FAM155A [Mus musculus] 245555 10891 0.01 0.02 1 Up 0.100784159 C77370 expressed sequence C77370 K02350|1|1e-28|133|oas:101110067|DNA polymerase zeta [EC:2.7.7.7] - - - - 106347 2910 0.01 0.023333333 1.222392421 Up 0.100784159 Ildr1 immunoglobulin-like domain containing receptor 1 - - - - - 100045792 2900 0.01 0.023333333 1.222392421 Up 0.100784159 Ect2l epithelial cell transforming sequence 2 oncogene-like K10299|1|7e-41|172|cmy:102940327|F-box protein 16 - - - gi|303523272|ref|NP_001181965.1|/0/epithelial cell-transforming sequence 2 oncogene-like [Mus musculus] 20464 7355 0.013333333 0.026666667 1 Up 0.100784159 Sim1 single-minded homolog 1 (Drosophila) K09100|1|0.0|1498|mmu:20464|single-minded GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity "GO:0035295//tube development;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication" gi|153945860|ref|NP_035506.2|/0/single-minded homolog 1 [Mus musculus] 329207 3851 0.02 0.01 -1 Down 0.100784159 Rbm44 RNA binding motif protein 44 - GO:0044424;GO:0044421 GO:0003676//nucleic acid binding;GO:0042802//identical protein binding - gi|85701905|ref|NP_001028580.1|/0/RNA-binding protein 44 [Mus musculus] 16769 3478 0.01 0.02 1 Up 0.100784159 Dsg4 desmoglein 4 K07599|1|0.0|1986|mmu:16769|desmoglein 4 GO:0031224//intrinsic component of membrane;GO:0005911//cell-cell junction GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion;GO:0022405//hair cycle process;GO:0009913//epidermal cell differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway gi|31621307|ref|NP_853543.1|/0/desmoglein-4 preproprotein [Mus musculus] 330917 3346 0.023333333 0.01 -1.222392421 Down 0.100784159 Gm27162 predicted gene 27162 - - - - - 381229 3345 0.02 0.01 -1 Down 0.100784159 Cfap58 cilia and flagella associated protein 58 K20478|1|3e-27|127|dre:557772|golgin subfamily B member 1 - - - - 83557 3480 0.01 0.02 1 Up 0.100784159 Lin28a lin-28 homolog A (C. elegans) K18754|1|9e-106|387|mmu:83557|protein lin-28 GO:0031981//nuclear lumen;GO:0035770//ribonucleoprotein granule GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003723//RNA binding "GO:0006351//transcription, DNA-templated;GO:0006412//translation;GO:0003006//developmental process involved in reproduction;GO:0010586//miRNA metabolic process;GO:0010001//glial cell differentiation;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0030182//neuron differentiation" gi|22003878|ref|NP_665832.1|/8.10244e-105/protein lin-28 homolog A [Mus musculus] 218624 3680 0.02 0.01 -1 Down 0.100784159 Il31ra interleukin 31 receptor A K05060|1|1e-67|261|cmk:103177817|interleukin 6 signal transducer - - GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0002573//myeloid leukocyte differentiation;GO:0008283//cell proliferation gi|568984405|ref|XP_006517682.1|/0/PREDICTED: interleukin-31 receptor subunit alpha isoform X2 [Mus musculus] 100286843 3174 0.01 0.023333333 1.222392421 Up 0.100784159 Gm16325 predicted gene 16325 K09512|1|6e-30|135|mgp:100546860|DnaJ homolog subfamily B member 6;K09509|4|3e-29|133|mcf:102124732|DnaJ homolog subfamily B member 3 - - - - 83563 4133 0.02 0.01 -1 Down 0.100784159 Usp26 ubiquitin specific peptidase 26 K11850|1|0.0|1587|mmu:83563|ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0070646//protein modification by small protein removal;GO:0019941//modification-dependent protein catabolic process "gi|148697162|gb|EDL29109.1|/0/ubiquitin specific peptidase 26, partial [Mus musculus]" 268451 3145 0.023333333 0.01 -1.222392421 Down 0.100784159 Rab11fip4 RAB11 family interacting protein 4 (class II) K12485|1|0.0|1156|mmu:268451|Rab11 family-interacting protein 3/4 "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0032155;GO:0010008//endosome membrane" GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0017016//Ras GTPase binding GO:0051234//establishment of localization;GO:0044763 gi|28202067|ref|NP_780752.1|/0/rab11 family-interacting protein 4 [Mus musculus] 75328 2679 0.023333333 0.01 -1.222392421 Down 0.100784159 4930563D23Rik RIKEN cDNA 4930563D23 gene - - - - gi|30794180|ref|NP_083528.1|/3.71054e-147/uncharacterized protein C21orf140 homolog [Mus musculus] 229722 3326 0.02 0.01 -1 Down 0.100784159 5330417C22Rik RIKEN cDNA 5330417C22 gene K04659|1|1e-08|65.5|crg:105319080|thrombospondin 2/3/4/5 - - - gi|568922649|ref|XP_006501474.1|/0/PREDICTED: UPF0577 protein KIAA1324 isoform X2 [Mus musculus] 20190 15362 0.01 0.02 1 Up 0.100784159 Ryr1 "ryanodine receptor 1, skeletal muscle" K04961|1|0.0|8764|mmu:20190|ryanodine receptor 1 GO:0032991//macromolecular complex;GO:0005789//endoplasmic reticulum membrane;GO:0016528//sarcoplasm;GO:0042383//sarcolemma;GO:0031224//intrinsic component of membrane;GO:0030017//sarcomere GO:0046872//metal ion binding;GO:0019899//enzyme binding GO:0003007//heart morphogenesis;GO:0008544//epidermis development;GO:0006936//muscle contraction;GO:0001503//ossification;GO:0007519//skeletal muscle tissue development;GO:0051209//release of sequestered calcium ion into cytosol;GO:0031000//response to caffeine gi|145046267|ref|NP_033135.2|/0/ryanodine receptor 1 [Mus musculus] 237831 3285 0.01 0.02 1 Up 0.100784159 Slc13a5 "solute carrier family 13 (sodium-dependent citrate transporter), member 5" "K14445|1|0.0|1066|mmu:237831|solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5" GO:0044459;GO:0031224//intrinsic component of membrane GO:0015556//C4-dicarboxylate transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0015142//tricarboxylic acid transmembrane transporter activity GO:0015744//succinate transport;GO:0044763;GO:0006842//tricarboxylic acid transport;GO:0030001//metal ion transport gi|51921291|ref|NP_001004148.1|/0/solute carrier family 13 member 5 [Mus musculus] 14175 3030 0.01 0.023333333 1.222392421 Up 0.100784159 Fgf4 fibroblast growth factor 4 K04358|1|9e-86|321|mmu:14175|fibroblast growth factor GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0070851//growth factor receptor binding GO:0006366//transcription from RNA polymerase II promoter;GO:0097094//craniofacial suture morphogenesis;GO:0008283//cell proliferation;GO:0042476//odontogenesis;GO:0006915//apoptotic process;GO:0030326//embryonic limb morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:0030154//cell differentiation;GO:0043410//positive regulation of MAPK cascade gi|66955870|ref|NP_034332.2|/7.94675e-85/fibroblast growth factor 4 precursor [Mus musculus] 230590 2289 0.01 0.023333333 1.222392421 Up 0.100784159 Zyg11a "zyg-11 family member A, cell cycle regulator" K10350|1|0.0|1396|mmu:230590|Zyg-11 protein homolog - - - gi|269308195|ref|NP_001161408.1|/0/protein zyg-11 homolog A [Mus musculus] 116837 3900 0.01 0.02 1 Up 0.100784159 Rims1 regulating synaptic membrane exocytosis 1 K15291|1|0.0|2399|mmu:116837|regulating synaptic membrane exocytosis protein 1 - - - - 327766 5123 0.023333333 0.01 -1.222392421 Down 0.100784159 Tmem26 transmembrane protein 26 - GO:0031224//intrinsic component of membrane - - gi|74180704|dbj|BAE25574.1|/4.60727e-176/unnamed protein product [Mus musculus] 54418 6461 0.026666667 0.013333333 -1 Down 0.100784159 Fmn2 formin 2 K02184|1|0.0|1353|mmu:54418|formin 2 GO:0005856//cytoskeleton;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part - GO:0001666//response to hypoxia;GO:0012501//programmed cell death;GO:0033554//cellular response to stress;GO:0007010//cytoskeleton organization;GO:0007292//female gamete generation;GO:0007143//female meiotic division;GO:0007127//meiosis I;GO:0009895;GO:0032502//developmental process gi|160707879|ref|NP_062318.2|/0/formin-2 [Mus musculus] 75761 2292 0.01 0.023333333 1.222392421 Up 0.100784159 Apol7a apolipoprotein L 7a K14480|1|3e-113|412|mmu:75761|apolipoprotein L - - - gi|257467561|ref|NP_083695.2|/2.4717e-112/apolipoprotein L 7a [Mus musculus] 15218 3270.02 0.023333333 0.01 -1.222392421 Down 0.100784159 Foxn1 forkhead box N1 K09407|1|0.0|1132|mmu:15218|forkhead box protein N - - - gi|568971739|ref|XP_006532328.1|/0/PREDICTED: forkhead box protein N1 isoform X3 [Mus musculus] 75870 2985 0.01 0.023333333 1.222392421 Up 0.100784159 Tcam1 testicular cell adhesion molecule 1 K06769|1|1e-94|350|mdo:100013186|intercellular adhesion molecule 5 GO:0016021//integral component of membrane - GO:0007155//cell adhesion gi|568976203|ref|XP_006534461.1|/0/PREDICTED: testicular cell adhesion molecule 1 isoform X2 [Mus musculus] 18431 3120 0.01 0.023333333 1.222392421 Up 0.100784159 Oca2 oculocutaneous albinism II "K14444|1|2e-06|58.2|chx:102168419|solute carrier family 13 (sodium/sulfate cotransporter), member 1/4" GO:0031224//intrinsic component of membrane;GO:0030659//cytoplasmic vesicle membrane GO:0015103//inorganic anion transmembrane transporter activity GO:0050931//pigment cell differentiation;GO:0015698//inorganic anion transport;GO:0006582//melanin metabolic process;GO:0007281//germ cell development gi|11230776|ref|NP_068679.1|/0/P protein [Mus musculus] 218103 2974 0.023333333 0.01 -1.222392421 Down 0.100784159 Slc17a2 "solute carrier family 17 (sodium phosphate), member 2" "K12300|1|0.0|731|cge:100755263|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 1/2/3/4" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0030001//metal ion transport;GO:0044763 gi|81871946|sp|Q5SZA1.1|NPT3_MOUSE/0/RecName: Full=Sodium-dependent phosphate transport protein 3; AltName: Full=Na(+)/PI cotransporter 3; AltName: Full=Sodium/phosphate cotransporter 3; AltName: Full=Solute carrier family 17 member 2 241877 3923 0.02 0.01 -1 Down 0.100784159 Slc10a5 "solute carrier family 10 (sodium/bile acid cotransporter family), member 5" "K14343|1|0.0|760|mmu:241877|solute carrier family 10 (sodium/bile acid cotransporter), member 3/5" GO:0031224//intrinsic component of membrane GO:0005343//organic acid:sodium symporter activity GO:0030001//metal ion transport gi|58082065|ref|NP_001010834.1|/0/sodium/bile acid cotransporter 5 precursor [Mus musculus] 320616 3188 0.02 0.01 -1 Down 0.100784159 B130006D01Rik RIKEN cDNA B130006D01 gene - - - - gi|26336847|dbj|BAC32107.1|/4.20759e-68/unnamed protein product [Mus musculus] 381983 4863.09 0.023333333 0.01 -1.222392421 Down 0.100784159 Lmtk3 lemur tyrosine kinase 3 K08899|1|0.0|1263|rno:691056|lemur tyrosine kinase 3 [EC:2.7.10.1] GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464 GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550 GO:0010921//regulation of phosphatase activity;GO:0006464//cellular protein modification process;GO:0010921//regulation of phosphatase activity;GO:0006464//cellular protein modification process;GO:0010921//regulation of phosphatase activity;GO:0006464//cellular protein modification process gi|568948028|ref|XP_006541024.1|/0/PREDICTED: serine/threonine-protein kinase LMTK3 isoform X3 [Mus musculus] 73254 4682 0.023333333 0.01 -1.222392421 Down 0.100784159 Ccdc18 coiled-coil domain containing 18 K20478|1|2e-52|211|dre:557772|golgin subfamily B member 1 - - - gi|58037313|ref|NP_082757.1|/0/coiled-coil domain-containing protein 18 [Mus musculus] 15405 3056 0.01 0.02 1 Up 0.100784159 Hoxa9 homeobox A9 K09294|1|8e-125|451|mmu:15405|homeobox protein HoxA/B/C/D9 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding "GO:0003002//regionalization;GO:0001775//cell activation;GO:0048732//gland development;GO:0001501//skeletal system development;GO:0030099//myeloid cell differentiation;GO:0006351//transcription, DNA-templated;GO:0030326//embryonic limb morphogenesis;GO:0003002//regionalization;GO:0001775//cell activation;GO:0048732//gland development;GO:0001501//skeletal system development;GO:0030099//myeloid cell differentiation;GO:0006351//transcription, DNA-templated;GO:0030326//embryonic limb morphogenesis" gi|469832273|ref|NP_001264167.1|/4.9374e-151/homeobox protein Hox-A9 isoform 2 [Mus musculus] 76670 3551 0.02 0.01 -1 Down 0.100784159 Cfap70 cilia and flagella associated protein 70 - - - - gi|254692940|ref|NP_083974.1|/0/tetratricopeptide repeat protein 18 isoform 3 [Mus musculus] 54652 6075 0.023333333 0.01 -1.222392421 Down 0.100784159 Cacna1f "calcium channel, voltage-dependent, alpha 1F subunit" K04853|1|0.0|3515|mmu:54652|voltage-dependent calcium channel L type alpha-1F GO:0034704//calcium channel complex;GO:0043025//neuronal cell body GO:0005245//voltage-gated calcium channel activity;GO:0043169//cation binding GO:0016358//dendrite development;GO:0043010//camera-type eye development;GO:0006816//calcium ion transport;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0007601//visual perception;GO:0034220//ion transmembrane transport;GO:0001505//regulation of neurotransmitter levels;GO:0006875//cellular metal ion homeostasis gi|115648151|ref|NP_062528.2|/0/voltage-dependent L-type calcium channel subunit alpha-1F [Mus musculus] 381759 2886 0.023333333 0.01 -1.222392421 Down 0.100784159 Wee2 WEE1 homolog 2 (S. pombe) K06632|1|0.0|1101|mmu:381759|wee1-like protein kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0046872//metal ion binding;GO:0004713//protein tyrosine kinase activity GO:0007135//meiosis II;GO:0001775//cell activation;GO:0000087//mitotic M phase;GO:0006464//cellular protein modification process;GO:0007127//meiosis I;GO:0006796//phosphate-containing compound metabolic process;GO:0006997//nucleus organization;GO:0010721//negative regulation of cell development "gi|148681638|gb|EDL13585.1|/0/cDNA sequence BC052883, isoform CRA_b, partial [Mus musculus]" 242253 3082 0.023333333 0.01 -1.222392421 Down 0.100784159 Wdr63 WD repeat domain 63 "K17770|1|6e-146|521|smm:Smp_136210|mitochondrial import receptor subunit TOM20;K11143|2|2e-26|124|nve:NEMVE_v1g186877|dynein intermediate chain 2, axonemal" - - - gi|197927139|ref|NP_766452.2|/0/WD repeat-containing protein 63 [Mus musculus] 64654 2702 0.023333333 0.01 -1.222392421 Down 0.100784159 Fgf23 fibroblast growth factor 23 K04358|1|3e-132|475|mmu:64654|fibroblast growth factor GO:0044421 GO:0005104//fibroblast growth factor receptor binding "GO:0006351//transcription, DNA-templated;GO:0001649//osteoblast differentiation;GO:0006793//phosphorus metabolic process;GO:0046879//hormone secretion;GO:0006066//alcohol metabolic process;GO:0030279//negative regulation of ossification;GO:0010979;GO:0072502;GO:0006817//phosphate ion transport;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0006706//steroid catabolic process" gi|12083589|ref|NP_073148.1|/2.88512e-131/fibroblast growth factor 23 precursor [Mus musculus] 23937 2703 0.01 0.023333333 1.222392421 Up 0.100784159 Mab21l2 mab-21-like 2 (C. elegans) K17834|1|7e-16|89.0|cge:100758179|cyclic GMP-AMP synthase [EC:2.7.7.86] GO:0043231//intracellular membrane-bounded organelle - GO:0009790//embryo development;GO:0010171//body morphogenesis;GO:0008283//cell proliferation;GO:0001654//eye development gi|521036477|gb|EPQ18255.1|/0/Protein mab-21-like 1 [Myotis brandtii] 16846 3257 0.02 0.01 -1 Down 0.100784159 Lep leptin K05424|1|2e-79|300|mmu:16846|leptin GO:0044421 GO:0051427//hormone receptor binding GO:0006915//apoptotic process;GO:0019229//regulation of vasoconstriction;GO:0007631//feeding behavior;GO:0032275//luteinizing hormone secretion;GO:0030282//bone mineralization;GO:0006868//glutamine transport;GO:0070091//glucagon secretion;GO:0015980//energy derivation by oxidation of organic compounds;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0007159//leukocyte cell-cell adhesion;GO:0014070//response to organic cyclic compound;GO:0040014//regulation of multicellular organism growth;GO:0016125//sterol metabolic process;GO:0009967//positive regulation of signal transduction;GO:0072593//reactive oxygen species metabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0030073//insulin secretion;GO:0032096//negative regulation of response to food;GO:0035733//hepatic stellate cell activation;GO:0007262//STAT protein import into nucleus;GO:0045927//positive regulation of growth;GO:0030099//myeloid cell differentiation;GO:0006071//glycerol metabolic process;GO:0033591//response to L-ascorbic acid;GO:0032278;GO:0030299//intestinal cholesterol absorption;GO:0048511//rhythmic process;GO:0021953//central nervous system neuron differentiation;GO:0044703;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0008585//female gonad development;GO:0019216//regulation of lipid metabolic process;GO:0006094//gluconeogenesis;GO:0006950//response to stress;GO:0051093//negative regulation of developmental process;GO:0000165//MAPK cascade;GO:0006694//steroid biosynthetic process;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0014897;GO:0032526//response to retinoic acid;GO:0008286//insulin receptor signaling pathway;GO:0001816//cytokine production;GO:0006631//fatty acid metabolic process gi|6678678|ref|NP_032519.1|/1.58048e-78/leptin precursor [Mus musculus] 83379 3439 0.02 0.01 -1 Down 0.100784159 Klb klotho beta K14756|1|0.0|899|cmk:103177202|klotho [EC:3.2.1.31] GO:0031224//intrinsic component of membrane "GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0019838//growth factor binding" GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0008283//cell proliferation;GO:0044238//primary metabolic process gi|13626032|ref|NP_112457.1|/0/beta-klotho [Mus musculus] 381058 2666 0.01 0.023333333 1.222392421 Up 0.100784159 Unc93a unc-93 homolog A (C. elegans) K16600|1|5e-166|587|gga:421566|tubulin polyglutamylase TTLL2 [EC:6.-.-.-];K02835|2|1e-11|75.1|cin:100181435|peptide chain release factor 1 GO:0031224//intrinsic component of membrane - - gi|40445395|ref|NP_954860.1|/0/protein unc-93 homolog A [Mus musculus] 319196 2723 0.01 0.023333333 1.222392421 Up 0.100784159 Ankef1 ankyrin repeat and EF-hand domain containing 1 K10799|1|1e-21|108|ame:413032|tankyrase [EC:2.4.2.30] - GO:0046872//metal ion binding - gi|28316764|ref|NP_783598.1|/0/ankyrin repeat and EF-hand domain-containing protein 1 [Mus musculus] 19374 3393 0.01 0.02 1 Up 0.100784159 Rag2 recombination activating gene 2 K10988|1|0.0|1103|mmu:19374|recombination-activating protein 2 GO:0043231//intracellular membrane-bounded organelle GO:0043168//anion binding;GO:0042393//histone binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0005543//phospholipid binding GO:0002329//pre-B cell differentiation;GO:0035265//organ growth;GO:0030217//T cell differentiation;GO:0002562;GO:0006325//chromatin organization;GO:0042100//B cell proliferation gi|6677661|ref|NP_033046.1|/0/V(D)J recombination-activating protein 2 [Mus musculus] 381476 2818 0.01 0.023333333 1.222392421 Up 0.100784159 Stpg2 sperm tail PG rich repeat containing 2 - - - - gi|568923099|ref|XP_006501691.1|/0/PREDICTED: sperm-tail PG-rich repeat-containing protein 2 isoform X2 [Mus musculus] 15567 2747 0.01 0.023333333 1.222392421 Up 0.100784159 Slc6a4 "solute carrier family 6 (neurotransmitter transporter, serotonin), member 4" "K05037|1|0.0|1244|mmu:15567|solute carrier family 6 (neurotransmitter transporter, serotonin) member 4" GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0031090//organelle membrane;GO:0042995//cell projection;GO:0044444//cytoplasmic part GO:0008144//drug binding;GO:0003779//actin binding;GO:0017016//Ras GTPase binding;GO:0005328//neurotransmitter:sodium symporter activity;GO:0042802//identical protein binding;GO:0005275//amine transmembrane transporter activity;GO:0019905//syntaxin binding "GO:0021536//diencephalon development;GO:0048511//rhythmic process;GO:0051705;GO:0007611//learning or memory;GO:0010467//gene expression;GO:0015695//organic cation transport;GO:0035265//organ growth;GO:0032526//response to retinoic acid;GO:0007320//insemination;GO:0001963//synaptic transmission, dopaminergic;GO:0043627//response to estrogen;GO:0051259//protein oligomerization;GO:0051726//regulation of cell cycle;GO:0070305//response to cGMP;GO:0009887//organ morphogenesis;GO:0001504//neurotransmitter uptake;GO:0050880//regulation of blood vessel size;GO:0021930//cerebellar granule cell precursor proliferation;GO:0031667//response to nutrient levels;GO:0030182//neuron differentiation" gi|195972807|ref|NP_034614.2|/0/sodium-dependent serotonin transporter [Mus musculus] 226604 3012 0.01 0.023333333 1.222392421 Up 0.100784159 Gm4847 predicted gene 4847 K00485|1|0.0|1079|mmu:226604|dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8] GO:0043231//intracellular membrane-bounded organelle "GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen" GO:0044710 gi|256221898|ref|NP_001157784.1|/0/flavin-containing monooxygenase 12 [Mus musculus] 27206 6604 0.026666667 0.013333333 -1 Down 0.100784159 Nrk Nik related kinase K16313|1|0.0|2450|mmu:27206|Nik-related protein kinase [EC:2.7.11.1] - GO:0032550;GO:0030695//GTPase regulator activity;GO:0004672//protein kinase activity GO:0044703;GO:0048638//regulation of developmental growth;GO:0000186//activation of MAPKK activity;GO:0008283//cell proliferation gi|225543267|ref|NP_038752.2|/0/nik-related protein kinase [Mus musculus] 20277 2694.04 0.01 0.023333333 1.222392421 Up 0.100784159 Scnn1b "sodium channel, nonvoltage-gated 1 beta" K04825|1|0.0|1282|mmu:20277|amiloride-sensitive sodium channel subunit beta GO:0044459;GO:0009986//cell surface;GO:0034703//cation channel complex;GO:0044459;GO:0009986//cell surface;GO:0034703//cation channel complex;GO:0044459;GO:0009986//cell surface;GO:0034703//cation channel complex GO:0019904//protein domain specific binding;GO:0005272//sodium channel activity;GO:0019904//protein domain specific binding;GO:0005272//sodium channel activity;GO:0019904//protein domain specific binding;GO:0005272//sodium channel activity "GO:0006814//sodium ion transport;GO:0007606//sensory perception of chemical stimulus;GO:0044319//wound healing, spreading of cells;GO:0006814//sodium ion transport;GO:0007606//sensory perception of chemical stimulus;GO:0044319//wound healing, spreading of cells;GO:0006814//sodium ion transport;GO:0007606//sensory perception of chemical stimulus;GO:0044319//wound healing, spreading of cells" gi|6755412|ref|NP_035455.1|/0/amiloride-sensitive sodium channel subunit beta [Mus musculus] 330890 2637 0.01 0.023333333 1.222392421 Up 0.100784159 Piwil4 piwi-like RNA-mediated gene silencing 4 K02156|1|0.0|1744|mmu:330890|aubergine GO:0043231//intracellular membrane-bounded organelle;GO:0043186//P granule GO:0003723//RNA binding GO:0006412//translation;GO:0048869//cellular developmental process;GO:0016458//gene silencing;GO:0022403;GO:0048232//male gamete generation;GO:0034660//ncRNA metabolic process;GO:0006306//DNA methylation gi|52138556|ref|NP_808573.2|/0/piwi-like protein 4 [Mus musculus] 399570 2388 0.01 0.023333333 1.222392421 Up 0.100784159 Kank4os "KN motif and ankyrin repeat domains 4, opposite strand" - - - - - 75590 2714 0.023333333 0.01 -1.222392421 Down 0.100784159 Dusp9 dual specificity phosphatase 9 K18498|1|5e-142|508|mmu:75590|dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48] - - - "gi|148697947|gb|EDL29894.1|/4.03801e-141/dual specificity phosphatase 9, isoform CRA_c [Mus musculus]" 109904 3671 0.02 0.01 -1 Down 0.100784159 Mcf2 mcf.2 transforming sequence K01530|1|0.0|1343|tup:102501475|phospholipid-translocating ATPase [EC:3.6.3.1];K08810|2|8e-50|202|cmk:103183938|triple functional domain protein [EC:2.7.11.1] - GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0005488//binding;GO:0030695//GTPase regulator activity GO:0019222//regulation of metabolic process;GO:0031175//neuron projection development;GO:0019222//regulation of metabolic process;GO:0031175//neuron projection development;GO:0019222//regulation of metabolic process;GO:0031175//neuron projection development gi|576080548|ref|NP_001276659.1|/0/proto-oncogene DBL isoform 3 [Mus musculus] 217843 8870 0.023333333 0.01 -1.222392421 Down 0.100784159 Unc79 unc-79 homolog (C. elegans) - GO:0031224//intrinsic component of membrane - GO:0040007//growth;GO:0030534//adult behavior gi|313661493|ref|NP_001074486.2|/0/protein unc-79 homolog [Mus musculus] 211187 3408 0.02 0.01 -1 Down 0.100784159 Lrtm2 leucine-rich repeats and transmembrane domains 2 K06839|1|1e-19|101|sko:102806385|slit 2 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148667192|gb|EDK99608.1|/4.96717e-174/expressed sequence AI841794, partial [Mus musculus]" 100041581 2794 0.01 0.023333333 1.222392421 Up 0.100784159 Zkscan16 zinc finger with KRAB and SCAN domains 16 K09229|1|0.0|1522|mmu:100041581|KRAB and SCAN domains-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0010467//gene expression;GO:0044764 gi|150010617|ref|NP_001092793.1|/0/zinc finger protein 483 [Mus musculus] 237930 3223 0.01 0.023333333 1.222392421 Up 0.100784159 Ttll6 "tubulin tyrosine ligase-like family, member 6" K16582|1|0.0|1587|mmu:237930|tubulin polyglutamylase TTLL6/13 [EC:6.-.-.-] GO:0043231//intracellular membrane-bounded organelle GO:0016881//acid-amino acid ligase activity;GO:0008092//cytoskeletal protein binding GO:0007017//microtubule-based process;GO:0018200//peptidyl-glutamic acid modification gi|282847336|ref|NP_766387.2|/0/tubulin polyglutamylase TTLL6 [Mus musculus] 239789 4179 0.02 0.01 -1 Down 0.100784159 Gmnc geminin coiled-coil domain containing - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding GO:0006259//DNA metabolic process;GO:0044763;GO:0006259//DNA metabolic process;GO:0044763;GO:0006259//DNA metabolic process;GO:0044763 gi|71274117|ref|NP_001013783.1|/0/geminin coiled-coil domain-containing protein 1 isoform 1 [Mus musculus] 242594 3069 0.01 0.02 1 Up 0.100784159 1700024P16Rik RIKEN cDNA 1700024P16 gene K17698|1|2e-12|77.8|amj:102558591|FYN binding protein - - - gi|244790089|ref|NP_001156452.1|/0/uncharacterized protein C1orf168 homolog isoform b [Mus musculus] 268755 4054 0.02 0.01 -1 Down 0.100784159 Mir124a-1hg Mir124-1 host gene (non-protein coding) - - - - - 54003 3168 0.01 0.023333333 1.222392421 Up 0.100784159 Nell2 NEL-like 2 K01482|1|9e-58|228|xma:102227700|dimethylargininase [EC:3.5.3.18];K17307|3|5e-47|192|tad:TRIADDRAFT_53733|fibulin 1/2 GO:0044421;GO:0043005//neuron projection;GO:0043025//neuronal cell body;GO:0044424 GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding GO:0051260//protein homooligomerization;GO:0040007//growth gi|576067787|ref|NP_001276582.1|/0/protein kinase C-binding protein NELL2 precursor [Mus musculus] 93690 3860 0.01 0.02 1 Up 0.100784159 Gpr45 G protein-coupled receptor 45 K08409|1|0.0|704|mmu:93690|G protein-coupled receptor 45 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|532034304|ref|XP_005360056.1|/0/PREDICTED: probable G-protein coupled receptor 45 [Microtus ochrogaster] 241116 5718 0.01 0.02 1 Up 0.100784159 Ccdc108 coiled-coil domain containing 108 K17570|1|1e-08|65.9|asn:102388673|hydrocephalus-inducing protein GO:0031224//intrinsic component of membrane - - gi|87162476|ref|NP_001034584.1|/0/coiled-coil domain-containing protein 108 [Mus musculus] 208982 3615 0.01 0.02 1 Up 0.100784159 Hmgcll1 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1 K01640|1|0.0|684|mmu:208982|hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4] GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0016833//oxo-acid-lyase activity GO:0044249//cellular biosynthetic process "gi|33239379|ref|NP_776092.1|/0/3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic [Mus musculus]" 326623 5828 0.023333333 0.01 -1.222392421 Down 0.100784159 Tnfsf15 "tumor necrosis factor (ligand) superfamily, member 15" K05478|1|5e-153|545|mmu:326623|tumor necrosis factor ligand superfamily member 15 - - - - 229714 3157 0.01 0.02 1 Up 0.100784159 Gpr61 G protein-coupled receptor 61 K08414|1|0.0|728|cge:100772674|G protein-coupled receptor 61 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|625275780|ref|XP_007629503.1|/0/PREDICTED: LOW QUALITY PROTEIN: probable G-protein coupled receptor 61 [Cricetulus griseus] 116810 2970 0.023333333 0.01 -1.222392421 Down 0.100784159 Foxn4 forkhead box N4 K09407|1|0.0|993|mmu:116810|forkhead box protein N GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006355//regulation of transcription, DNA-templated;GO:0030182//neuron differentiation" gi|91598891|ref|NP_683737.2|/0/forkhead box protein N4 [Mus musculus] 331491 3658 0.01 0.02 1 Up 0.100784159 Fnd3c2 fibronectin type III domain containing 3C2 K12567|1|5e-36|156|spu:590007|titin [EC:2.7.11.1] - - - gi|257196223|ref|NP_001028596.2|/0/fibronectin type III domain containing 3C2 [Mus musculus] 20309 2127 0.01 0.023333333 1.222392421 Up 0.100784159 Cxcl15 chemokine (C-X-C motif) ligand 15 K10034|1|7e-93|344|mmu:20309|C-X-C motif chemokine 15;K10030|2|6e-17|92.0|fca:102901398|interleukin 8 GO:0044421 GO:0005125//cytokine activity;GO:0045236//CXCR chemokine receptor binding GO:0006952//defense response;GO:0048534//hematopoietic or lymphoid organ development;GO:0022402//cell cycle process;GO:0033554//cellular response to stress;GO:0050927//positive regulation of positive chemotaxis;GO:0007155//cell adhesion;GO:0045069//regulation of viral genome replication;GO:0006898//receptor-mediated endocytosis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0030595//leukocyte chemotaxis gi|6755436|ref|NP_035469.1|/5.76151e-92/C-X-C motif chemokine 15 precursor [Mus musculus] 170677 4364 0.01 0.023333333 1.222392421 Up 0.100784159 Cdhr1 cadherin-related family member 1 K16501|1|0.0|1568|mmu:170677|cadherin-related family member 1 GO:0016021//integral component of membrane;GO:0001750//photoreceptor outer segment GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion;GO:0007601//visual perception "gi|148692950|gb|EDL24897.1|/0/protocadherin 21, partial [Mus musculus]" 76718 3957 0.02 0.01 -1 Down 0.100784159 Catsperg2 catsper channel auxiliary subunit gamma 2 K16894|1|0.0|2286|mmu:76718|cation channel sperm-associated protein subunit gamma GO:0005929//cilium;GO:0005891//voltage-gated calcium channel complex - GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|157951745|ref|NP_083990.2|/0/cation channel sperm-associated protein subunit gamma 2 precursor [Mus musculus] 70884 2691 0.01 0.023333333 1.222392421 Up 0.100784159 Ccdc81 coiled-coil domain containing 81 K04257|1|3e-28|130|aam:106488039|olfactory receptor;K14165|2|2e-18|97.1|mgp:100544144|atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48];K12484|3|4e-07|59.7|ola:101164078|Rab11 family-interacting protein 1/2/5;K10358|4|2e-06|57.8|cin:100186550|myosin VI;K16307|5|3e-06|57.0|nle:100601314|serine/threonine-protein kinase MRCK [EC:2.7.11.1] - - - gi|244790085|ref|NP_001156451.1|/0/coiled-coil domain-containing protein 81 [Mus musculus] 170729 4010 0.02 0.01 -1 Down 0.100784159 Scrt1 scratch family zinc finger 1 K09219|1|2e-80|304|ngi:103735254|scratch GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated" gi|982264581|ref|XP_015310311.1|/1.37928e-79/PREDICTED: transcriptional repressor scratch 1 [Macaca fascicularis] 20465 3670 0.01 0.02 1 Up 0.100784159 Sim2 single-minded homolog 2 (Drosophila) K09100|1|0.0|1168|mmu:20465|single-minded GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity GO:0030323//respiratory tube development;GO:0048869//cellular developmental process;GO:0007154//cell communication;GO:0006366//transcription from RNA polymerase II promoter;GO:0009790//embryo development gi|119226237|ref|NP_035507.2|/0/single-minded homolog 2 [Mus musculus] 17879 6058 0.026666667 0.013333333 -1 Down 0.100784159 Myh1 "myosin, heavy polypeptide 1, skeletal muscle, adult" K10352|1|0.0|3297|mmu:17879|myosin heavy chain GO:0030017//sarcomere;GO:0016460//myosin II complex;GO:0044291//cell-cell contact zone GO:0008092//cytoskeletal protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0003012//muscle system process gi|82524274|ref|NP_109604.1|/0/myosin-1 [Mus musculus] 235604 3031 0.023333333 0.01 -1.222392421 Down 0.100784159 Camkv CaM kinase-like vesicle-associated K08812|1|0.0|858|mmu:235604|CaM kinase-like vesicle-associated [EC:2.7.11.-] GO:0012506//vesicle membrane GO:0016301//kinase activity;GO:0005515//protein binding;GO:0032550 GO:0006464//cellular protein modification process "gi|148689290|gb|EDL21237.1|/0/CaM kinase-like vesicle-associated, partial [Mus musculus]" 13409 4073 0.01 0.02 1 Up 0.100784159 Tmc1 transmembrane channel-like gene family 1 K10877|1|1e-33|148|tsp:Tsp_10860|DNA repair and recombination protein RAD54B [EC:3.6.4.-] GO:0009986//cell surface;GO:0032421//stereocilium bundle;GO:0031224//intrinsic component of membrane - GO:0050877//neurological system process;GO:0060004//reflex;GO:0042491//auditory receptor cell differentiation gi|20127392|ref|NP_083229.1|/0/transmembrane channel-like protein 1 [Mus musculus] 72395 3543 0.01 0.02 1 Up 0.100784159 2610028E06Rik RIKEN cDNA 2610028E06 gene - - - - - 243911 3122 0.01 0.02 1 Up 0.100784159 Kirrel2 kin of IRRE like 2 (Drosophila) K18273|1|5e-79|298|asn:102383405|alpha-tectorin;K17341|3|3e-34|150|cfa:491293|hemicentin GO:0036056;GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0007155//cell adhesion "gi|148692073|gb|EDL24020.1|/0/kin of IRRE like 2 (Drosophila), isoform CRA_a, partial [Mus musculus]" 319200 2497 0.01 0.023333333 1.222392421 Up 0.100784159 Gpr82 G protein-coupled receptor 82 K08420|1|3e-168|594|mmu:319200|G protein-coupled receptor 82 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|28316782|ref|NP_783600.1|/2.97449e-167/probable G-protein coupled receptor 82 [Mus musculus] 791361 2842 0.023333333 0.01 -1.222392421 Down 0.100784159 Gm16497 predicted gene 16497 - - - - gi|40556843|gb|AAR87779.1|/4.26134e-32/unknown [Mus musculus] 17885 6149 0.026666667 0.013333333 -1 Down 0.100784159 Myh8 "myosin, heavy polypeptide 8, skeletal muscle, perinatal" K10352|1|0.0|3368|mmu:17885|myosin heavy chain - - - - 103098 3563 0.01 0.02 1 Up 0.100784159 Slc6a15 "solute carrier family 6 (neurotransmitter transporter), member 15" "K05048|1|0.0|1359|mmu:103098|solute carrier family 6 (neurotransmitter transporter, amino acid/orphan) member 15/16/17/18/20" GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0005326//neurotransmitter transporter activity;GO:0005283//sodium:amino acid symporter activity;GO:0005326//neurotransmitter transporter activity;GO:0005283//sodium:amino acid symporter activity GO:0006814//sodium ion transport;GO:0003333//amino acid transmembrane transport;GO:0006814//sodium ion transport;GO:0003333//amino acid transmembrane transport gi|28202019|ref|NP_780537.1|/0/sodium-dependent neutral amino acid transporter B(0)AT2 [Mus musculus] 436240 3208 0.02 0.01 -1 Down 0.100784159 Foxr2 forkhead box R2 K09407|1|1e-18|98.6|rno:288736|forkhead box protein N GO:0043231//intracellular membrane-bounded organelle "GO:0003677//DNA binding;GO:0003700//transcription factor activity, sequence-specific DNA binding" "GO:0048856//anatomical structure development;GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organism development" gi|77861897|ref|NP_001030066.1|/4.24753e-177/forkhead box protein R2 [Mus musculus] 21683 7326 0.01 0.02 1 Up 0.100784159 Tecta tectorin alpha K18273|1|0.0|4543|mmu:21683|alpha-tectorin - - - - 241636 2965 0.023333333 0.01 -1.222392421 Down 0.100784159 Tgm6 transglutaminase 6 K05624|1|0.0|1305|rno:296152|transglutaminase 6 [EC:2.3.2.13] - "GO:0016755//transferase activity, transferring amino-acyl groups;GO:0043169//cation binding;GO:0016755//transferase activity, transferring amino-acyl groups;GO:0043169//cation binding;GO:0016755//transferase activity, transferring amino-acyl groups;GO:0043169//cation binding;GO:0016755//transferase activity, transferring amino-acyl groups;GO:0043169//cation binding" - gi|29244202|ref|NP_808394.1|/0/protein-glutamine gamma-glutamyltransferase 6 isoform 1 [Mus musculus] 12155 3086 0.01 0.023333333 1.222392421 Up 0.100784159 Bmp15 bone morphogenetic protein 15 K05498|1|0.0|786|mmu:12155|growth differentiation factor 9/9B - - - - 76206 3194 0.023333333 0.01 -1.222392421 Down 0.100784159 Gpr165 G protein-coupled receptor 165 K04210|1|0.0|743|ocu:100339518|G protein-coupled receptor 83 - - - - 17480 2701 0.01 0.023333333 1.222392421 Up 0.100784159 Mpl myeloproliferative leukemia virus oncogene K05082|1|0.0|1272|mmu:17480|thrombopoietin receptor GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0042592//homeostatic process;GO:0001817//regulation of cytokine production;GO:0042592//homeostatic process;GO:0001817//regulation of cytokine production;GO:0042592//homeostatic process;GO:0001817//regulation of cytokine production;GO:0042592//homeostatic process;GO:0001817//regulation of cytokine production gi|550822317|ref|NP_001272425.1|/0/thrombopoietin receptor isoform 3 precursor [Mus musculus] 381112 3278 0.01 0.02 1 Up 0.100784159 Arhgef33 Rho guanine nucleotide exchange factor (GEF) 33 K16727|1|5e-06|56.6|mcf:102130017|Rho guanine nucleotide exchange factor 10;K08878|2|6e-06|56.2|nve:NEMVE_v1g239294|breakpoint cluster region protein [EC:2.7.11.1] - - - gi|224282176|ref|NP_001138924.1|/0/rho guanine nucleotide exchange factor 33 [Mus musculus] 210274 5913 0.026666667 0.013333333 -1 Down 0.100784159 Shank2 SH3/ankyrin domain gene 2 K15009|1|0.0|2437|mmu:210274|SH3 and multiple ankyrin repeat domains protein GO:0044297//cell body;GO:0031090//organelle membrane;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0005882//intermediate filament;GO:0005887//integral component of plasma membrane;GO:0044297//cell body;GO:0031090//organelle membrane;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0005882//intermediate filament;GO:0005887//integral component of plasma membrane GO:0035254//glutamate receptor binding;GO:0019904//protein domain specific binding;GO:0035254//glutamate receptor binding;GO:0019904//protein domain specific binding GO:0007417//central nervous system development;GO:0007417//central nervous system development gi|164607122|ref|NP_001074839.2|/0/SH3 and multiple ankyrin repeat domains protein 2 isoform a [Mus musculus] 170484 3124 0.023333333 0.01 -1.222392421 Down 0.100784159 Nphs2 "nephrosis 2, podocin" K18268|1|2e-173|612|mmu:170484|podocin - - - - 14406 3911 0.02 0.01 -1 Down 0.100784159 Gabrg2 "gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2" K05186|1|0.0|907|rno:29709|gmma-aminobutyric acid receptor subunit gamma GO:0032589//neuron projection membrane;GO:0097060//synaptic membrane;GO:0044424;GO:0034702//ion channel complex;GO:0032589//neuron projection membrane;GO:0097060//synaptic membrane;GO:0044424;GO:0034702//ion channel complex GO:0030594//neurotransmitter receptor activity;GO:0005253//anion channel activity;GO:0005488//binding;GO:0005230//extracellular ligand-gated ion channel activity;GO:0016917//GABA receptor activity;GO:0030594//neurotransmitter receptor activity;GO:0005253//anion channel activity;GO:0005488//binding;GO:0005230//extracellular ligand-gated ion channel activity;GO:0016917//GABA receptor activity GO:0015698//inorganic anion transport;GO:0007270//neuron-neuron synaptic transmission;GO:0007275//multicellular organism development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0015698//inorganic anion transport;GO:0007270//neuron-neuron synaptic transmission;GO:0007275//multicellular organism development;GO:0007186//G-protein coupled receptor signaling pathway gi|444741657|ref|NP_803127.3|/0/gamma-aminobutyric acid receptor subunit gamma-2 isoform 2 precursor [Mus musculus] 269053 3939 0.02 0.01 -1 Down 0.100784159 Gpr152 G protein-coupled receptor 152 K08436|1|0.0|823|mmu:269053|G protein-coupled receptor 152 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|46195446|ref|NP_996856.1|/0/probable G-protein coupled receptor 152 [Mus musculus] 329480 3267 0.02 0.01 -1 Down 0.100784159 Wt1os "Wilms tumor 1 homolog, opposite strand" - - - - - 195434 3695 0.01 0.02 1 Up 0.100784159 Utp14b UTP14B small subunit processome component K14567|1|0.0|1403|mmu:195434|U3 small nucleolar RNA-associated protein 14 GO:0030684//preribosome;GO:0005634//nucleus;GO:0030684//preribosome;GO:0005634//nucleus GO:0005488//binding;GO:0005488//binding GO:0048869//cellular developmental process;GO:0022403;GO:0042254//ribosome biogenesis;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0022403;GO:0042254//ribosome biogenesis;GO:0048232//male gamete generation gi|75992943|ref|NP_001001981.2|/0/U3 small nucleolar RNA-associated protein 14 homolog B [Mus musculus] 140498 3317 0.01 0.02 1 Up 0.100784159 Rxfp2 relaxin/insulin-like family peptide receptor 2 K04307|1|0.0|1334|mmu:140498|relaxin family peptide receptor 2 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004930//G-protein coupled receptor activity;GO:0042277//peptide binding;GO:0004930//G-protein coupled receptor activity;GO:0042277//peptide binding;GO:0004930//G-protein coupled receptor activity;GO:0042277//peptide binding GO:0008283//cell proliferation;GO:0008406//gonad development;GO:0006915//apoptotic process;GO:0006171//cAMP biosynthetic process;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0008406//gonad development;GO:0006915//apoptotic process;GO:0006171//cAMP biosynthetic process;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0008406//gonad development;GO:0006915//apoptotic process;GO:0006171//cAMP biosynthetic process;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway gi|575771784|ref|NP_001276495.1|/0/relaxin receptor 2 isoform 3 precursor [Mus musculus] 14425 3684 0.01 0.02 1 Up 0.100784159 Galnt3 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 K00710|1|0.0|1309|mmu:14425|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding;GO:0008376//acetylgalactosaminyltransferase activity GO:0006493//protein O-linked glycosylation gi|162951828|ref|NP_056551.2|/0/polypeptide N-acetylgalactosaminyltransferase 3 [Mus musculus] 100312476 921 0.023333333 0.01 -1.222392421 Down 0.100784159 Vmn1r238 "vomeronasal 1 receptor, 238" K04614|1|5e-173|608|mmu:100042437|vomeronasal1 receptor GO:0016021//integral component of membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0010033//response to organic substance "gi|285394352|ref|NP_001161011.1|/7.44343e-176/vomeronasal 1 receptor, 238 [Mus musculus]" 22348 2805 0.01 0.02 1 Up 0.100784159 Slc32a1 "solute carrier family 32 (GABA vesicular transporter), member 1" K15015|1|0.0|1009|mmu:22348|solute carrier family 32 (vesicular inhibitory amino acid transporter) GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0045202//synapse;GO:0030136//clathrin-coated vesicle;GO:0060187//cell pole;GO:0012506//vesicle membrane;GO:0043679//axon terminus GO:0005280//hydrogen:amino acid symporter activity GO:0006814//sodium ion transport;GO:0006818//hydrogen transport;GO:0044767//single-organism developmental process;GO:0006865//amino acid transport gi|125490380|ref|NP_033534.2|/0/vesicular inhibitory amino acid transporter [Mus musculus] 213765 3731 0.02 0.01 -1 Down 0.100784159 Nutm1 "NUT midline carcinoma, family member 1" - GO:0043231//intracellular membrane-bounded organelle - - gi|27369728|ref|NP_766109.1|/0/NUT family member 1 [Mus musculus] 70061 2863 0.01 0.023333333 1.222392421 Up 0.100784159 Sdr9c7 "4short chain dehydrogenase/reductase family 9C, member 7" K13369|1|7e-99|364|amj:102571332|17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239];K11154|2|8e-98|361|mdo:100011050|retinol dehydrogenase 16 [EC:1.1.1.-] GO:0044424 "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0044710 gi|28076941|ref|NP_081577.1|/8.29739e-177/short-chain dehydrogenase/reductase family 9C member 7 [Mus musculus] 353346 3433 0.01 0.02 1 Up 0.100784159 Gpr141 G protein-coupled receptor 141 K08429|1|8e-140|501|mmu:353346|G protein-coupled receptor 141 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|282165829|ref|NP_861419.3|/6.46257e-139/probable G-protein coupled receptor 141 [Mus musculus] 11551 3818 0.02 0.01 -1 Down 0.100784159 Adra2a "adrenergic receptor, alpha 2a" K04138|1|0.0|778|mmu:11551|adrenergic receptor alpha-2A GO:0043234//protein complex;GO:0044459;GO:0016021//integral component of membrane;GO:0044424 GO:0004936//alpha-adrenergic receptor activity;GO:0031690//adrenergic receptor binding;GO:0019900//kinase binding;GO:0032403//protein complex binding;GO:0042802//identical protein binding;GO:1901338;GO:0046983//protein dimerization activity GO:0006954//inflammatory response;GO:0001775//cell activation;GO:0033555//multicellular organismal response to stress;GO:0045986//negative regulation of smooth muscle contraction;GO:0007010//cytoskeleton organization;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0015980//energy derivation by oxidation of organic compounds;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0022600//digestive system process;GO:0042311//vasodilation;GO:0006509//membrane protein ectodomain proteolysis;GO:0009895;GO:0006259//DNA metabolic process;GO:0016477//cell migration;GO:0017156//calcium ion regulated exocytosis;GO:0007265//Ras protein signal transduction;GO:0014060;GO:0007599//hemostasis;GO:0044703;GO:0006813//potassium ion transport;GO:0008283//cell proliferation;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0032413//negative regulation of ion transmembrane transporter activity;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0050796//regulation of insulin secretion;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0006816//calcium ion transport;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0009725//response to hormone;GO:0014061//regulation of norepinephrine secretion;GO:0050951//sensory perception of temperature stimulus;GO:0001816//cytokine production gi|194353957|ref|NP_031443.4|/0/alpha-2A adrenergic receptor [Mus musculus] 252864 3121 0.01 0.023333333 1.222392421 Up 0.100784159 Dusp15 dual specificity phosphatase-like 15 K14165|1|7e-116|421|mmu:252864|atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] - - - gi|21919414|ref|NP_665687.1|/3.37413e-57/dual specificity protein phosphatase 15 isoform 2 [Mus musculus] 12745 4001 0.01 0.02 1 Up 0.100784159 Clgn calmegin K09551|1|0.0|1214|mmu:12745|calmegin - - - - 215378 2760 0.023333333 0.01 -1.222392421 Down 0.100784159 Brinp3 bone morphogenetic protein/retinoic acid inducible neural specific 3 - GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body - GO:0048731//system development;GO:0051726//regulation of cell cycle;GO:0048731//system development;GO:0051726//regulation of cell cycle gi|224809594|ref|NP_705767.3|/0/BMP/retinoic acid-inducible neural-specific protein 3 precursor [Mus musculus] 75973 3182 0.01 0.023333333 1.222392421 Up 0.100784159 Ccdc162 coiled-coil domain containing 162 K20283|1|3e-09|67.4|amj:102575628|golgin subfamily A member 4;K16464|4|7e-09|65.9|tup:102467969|centrosomal protein CEP250 - - - gi|568965753|ref|XP_006512962.1|/0/PREDICTED: coiled-coil domain containing 162 isoform X3 [Mus musculus] 69952 2876 0.01 0.02 1 Up 0.100784159 Tunar Tcl1 upstream neural differentiation associated RNA - - - - "gi|148686816|gb|EDL18763.1|/1.48487e-32/mCG53020, isoform CRA_b [Mus musculus]" 381260 3615 0.02 0.01 -1 Down 0.100784159 Gm973 predicted gene 973 - - - - gi|124244085|ref|NP_001013793.2|/0/uncharacterized protein KIAA2012 homolog [Mus musculus] 268756 2265 0.01 0.023333333 1.222392421 Up 0.100784159 Gulo gulonolactone (L-) oxidase K00103|1|0.0|885|mmu:268756|L-gulonolactone oxidase [EC:1.1.3.8] - - - - 628422 2589 0.01 0.023333333 1.222392421 Up 0.100784159 Vmn2r58 "vomeronasal 2, receptor 58" K04613|1|0.0|1488|mmu:637873|vomeronasal 2 receptor;K04612|2|0.0|1134|cge:100763896|calcium-sensing receptor - - - gi|157311584|ref|NP_001098525.1|/0/vomeronasal receptor Vmn2r58 precursor [Mus musculus] 71584 2614 0.023333333 0.01 -1.222392421 Down 0.100784159 Gdpd2 glycerophosphodiester phosphodiesterase domain containing 2 K01124|1|0.0|885|mmu:71584|glycerophosphoinositol inositolphosphodiesterase [EC:3.1.4.43] GO:0043232;GO:0031224//intrinsic component of membrane;GO:0043232;GO:0031224//intrinsic component of membrane GO:0043169//cation binding;GO:0008081//phosphoric diester hydrolase activity;GO:0043169//cation binding;GO:0008081//phosphoric diester hydrolase activity GO:0019400;GO:0019400 "gi|148682222|gb|EDL14169.1|/0/glycerophosphodiester phosphodiesterase domain containing 2, isoform CRA_a, partial [Mus musculus]" 432478 3454 0.02 0.01 -1 Down 0.100784159 Tmprss9 "transmembrane protease, serine 9" K09640|1|0.0|2155|mmu:432478|transmembrane protease serine 9 [EC:3.4.21.-] GO:0016021//integral component of membrane GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|755534803|ref|XP_006513908.2|/0/PREDICTED: transmembrane protease serine 9 isoform X4 [Mus musculus] 320614 2816 0.023333333 0.01 -1.222392421 Down 0.100784159 A330033J07Rik RIKEN cDNA A330033J07 gene - - - - "gi|148709101|gb|EDL41047.1|/3.90692e-62/mCG146154, partial [Mus musculus]" 21405 3203 0.01 0.02 1 Up 0.100784159 Hnf1a HNF1 homeobox A "K08036|1|0.0|1095|mmu:21405|transcription factor 1, hepatocyte nuclear factor 1-alpha" GO:0043234//protein complex;GO:0031513//nonmotile primary cilium;GO:0005634//nucleus "GO:0043566//structure-specific DNA binding;GO:0042802//identical protein binding;GO:0000975//regulatory region DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0046983//protein dimerization activity" GO:0031016//pancreas development;GO:0001894//tissue homeostasis;GO:0001701//in utero embryonic development;GO:0016055//Wnt signaling pathway;GO:0003006//developmental process involved in reproduction;GO:0015718//monocarboxylic acid transport;GO:0001707//mesoderm formation;GO:0015758//glucose transport;GO:0016125//sterol metabolic process;GO:0030301//cholesterol transport;GO:0030073//insulin secretion;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0010646//regulation of cell communication;GO:0033500//carbohydrate homeostasis;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0035564//regulation of kidney size;GO:0035108//limb morphogenesis;GO:0009746;GO:0006950//response to stress;GO:0006694//steroid biosynthetic process;GO:0016568//chromatin modification;GO:0006631//fatty acid metabolic process gi|166295202|ref|NP_033353.2|/0/hepatocyte nuclear factor 1-alpha [Mus musculus] 434412 3796 0.023333333 0.01 -1.222392421 Down 0.100784159 Gm20745 "predicted gene, 20745" - - - - - 20745 4665.01 0.01 0.023333333 1.222392421 Up 0.100784159 Spock1 "sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1" "K08136|1|1e-170|603|mmu:20745|sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican)" GO:0045202//synapse;GO:0033267;GO:0031012//extracellular matrix;GO:0005737//cytoplasm;GO:0044421;GO:0045202//synapse;GO:0033267;GO:0031012//extracellular matrix;GO:0005737//cytoplasm;GO:0044421;GO:0045202//synapse;GO:0033267;GO:0031012//extracellular matrix;GO:0005737//cytoplasm;GO:0044421;GO:0045202//synapse;GO:0033267;GO:0031012//extracellular matrix;GO:0005737//cytoplasm;GO:0044421;GO:0045202//synapse;GO:0033267;GO:0031012//extracellular matrix;GO:0005737//cytoplasm;GO:0044421 GO:0004866//endopeptidase inhibitor activity;GO:0046872//metal ion binding;GO:0004866//endopeptidase inhibitor activity;GO:0046872//metal ion binding;GO:0004866//endopeptidase inhibitor activity;GO:0046872//metal ion binding;GO:0004866//endopeptidase inhibitor activity;GO:0046872//metal ion binding;GO:0004866//endopeptidase inhibitor activity;GO:0046872//metal ion binding GO:0007417//central nervous system development;GO:0007162//negative regulation of cell adhesion;GO:0010466//negative regulation of peptidase activity;GO:0010975//regulation of neuron projection development;GO:0007154//cell communication;GO:0007162//negative regulation of cell adhesion;GO:0010466//negative regulation of peptidase activity;GO:0010975//regulation of neuron projection development;GO:0007154//cell communication;GO:0007162//negative regulation of cell adhesion;GO:0010466//negative regulation of peptidase activity;GO:0010975//regulation of neuron projection development;GO:0007154//cell communication;GO:0007162//negative regulation of cell adhesion;GO:0010466//negative regulation of peptidase activity;GO:0010975//regulation of neuron projection development;GO:0007154//cell communication;GO:0007162//negative regulation of cell adhesion;GO:0010466//negative regulation of peptidase activity;GO:0010975//regulation of neuron projection development;GO:0007154//cell communication gi|262050583|ref|NP_001159936.1|/0/testican-1 isoform 4 precursor [Mus musculus] 56544 2739 0.01 0.023333333 1.222392421 Up 0.100784159 Vmn2r1 "vomeronasal 2, receptor 1" K04613|1|0.0|1756|mmu:56544|vomeronasal 2 receptor GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0010033//response to organic substance gi|114145503|ref|NP_064302.2|/0/vomeronasal type-2 receptor 1 precursor [Mus musculus] 320256 5263 0.023333333 0.01 -1.222392421 Down 0.100784159 Dlec1 deleted in lung and esophageal cancer 1 K17570|1|9e-20|102|cjc:100396866|hydrocephalus-inducing protein - - - gi|226371688|ref|NP_796091.2|/0/deleted in lung and esophageal cancer protein 1 homolog [Mus musculus] 329064 3321 0.02 0.01 -1 Down 0.100784159 Pkd2l1 polycystic kidney disease 2-like 1 K04990|1|0.0|1430|mmu:329064|polycystin 2L1 GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0046872//metal ion binding;GO:0051393//alpha-actinin binding;GO:0005227//calcium activated cation channel activity;GO:0008527//taste receptor activity GO:0006814//sodium ion transport;GO:0010447//response to acidic pH;GO:0034220//ion transmembrane transport gi|225543361|ref|NP_852087.2|/0/polycystic kidney disease 2-like 1 protein [Mus musculus] 225600 4230 0.01 0.023333333 1.222392421 Up 0.100784159 Pde6a "phosphodiesterase 6A, cGMP-specific, rod, alpha" "K08718|1|0.0|1593|mmu:225600|rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha [EC:3.1.4.35]" GO:0016020//membrane "GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity" GO:0043010//camera-type eye development;GO:0050953//sensory perception of light stimulus;GO:0006874//cellular calcium ion homeostasis;GO:0007154//cell communication;GO:0009150//purine ribonucleotide metabolic process "gi|22122583|ref|NP_666198.1|/0/rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha [Mus musculus]" 100040591 3056 0.01 0.02 1 Up 0.100784159 Kcnj13 "potassium inwardly-rectifying channel, subfamily J, member 13" K05006|1|0.0|702|mmu:100040591|potassium inwardly-rectifying channel subfamily J member 13 - - - - 329716 1065 0.01 0.023333333 1.222392421 Up 0.100784159 BC107364 cDNA sequence BC107364 - - - - gi|371874231|ref|NP_001243109.1|/1.00106e-80/uncharacterized protein LOC329716 isoform 1 [Mus musculus] 56622 2920 0.01 0.02 1 Up 0.100784159 Adam21 a disintegrin and metallopeptidase domain 21 K08610|1|0.0|1526|mmu:56622|disintegrin and metalloproteinase domain-containing protein 21 [EC:3.4.24.-] - - - - 14545 3954 0.02 0.01 -1 Down 0.100784159 Gdap1 ganglioside-induced differentiation-associated-protein 1 K00799|1|6e-06|56.6|bfo:BRAFLDRAFT_75372|glutathione S-transferase [EC:2.5.1.18] GO:0031306//intrinsic component of mitochondrial outer membrane - GO:0033993//response to lipid;GO:0006605//protein targeting;GO:0007005//mitochondrion organization gi|74143411|dbj|BAE28787.1|/0/unnamed protein product [Mus musculus] 668620 3112 0.01 0.023333333 1.222392421 Up 0.100784159 Zfp936 zinc finger protein 936 K09228|1|0.0|1001|mmu:668620|KRAB domain-containing zinc finger protein - - - - 15223 2599 0.01 0.023333333 1.222392421 Up 0.100784159 Foxj1 forkhead box J1 K09402|1|0.0|697|mmu:15223|forkhead box protein J1 - - - gi|226693376|ref|NP_032266.3|/0/forkhead box protein J1 [Mus musculus] 114671 1771 0.02 0.01 -1 Down 0.100784159 4930444G20Rik RIKEN cDNA 4930444G20 gene K03345|1|0.0|989|mmu:114671|sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68] - GO:0008233//peptidase activity GO:0006915//apoptotic process;GO:0019538//protein metabolic process gi|163965379|ref|NP_444494.1|/0/SUMO/sentrin specific peptidase-like [Mus musculus] 17884 6037 0.02 0.01 -1 Down 0.100784159 Myh4 "myosin, heavy polypeptide 4, skeletal muscle" K10352|1|0.0|3368|mmu:17884|myosin heavy chain GO:0031981//nuclear lumen;GO:0005924//cell-substrate adherens junction;GO:0044291//cell-cell contact zone;GO:0016460//myosin II complex;GO:0030017//sarcomere GO:0008092//cytoskeletal protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0050896//response to stimulus;GO:0003012//muscle system process gi|67189167|ref|NP_034985.2|/0/myosin-4 [Mus musculus] 81018 3001 36.63333333 36.36333333 -0.010672527 Down 0.100737147 Rnf114 ring finger protein 114 K15697|1|6e-125|451|mmu:81018|RING finger protein 114 [EC:2.3.2.27] GO:0044464 GO:0046914//transition metal ion binding GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|27229275|ref|NP_109668.2|/5.05789e-124/E3 ubiquitin-protein ligase RNF114 [Mus musculus] 11767 1964 41.31 41.04666667 -0.009225992 Down 0.100643123 Ap1m1 "adaptor-related protein complex AP-1, mu subunit 1" K12393|1|0.0|849|mmu:11767|AP-1 complex subunit mu GO:0005764//lysosome;GO:0030136//clathrin-coated vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0012506//vesicle membrane;GO:0005802//trans-Golgi network GO:0005488//binding GO:0002478;GO:0043485//endosome to pigment granule transport;GO:0048753//pigment granule organization;GO:0048193//Golgi vesicle transport;GO:0050688//regulation of defense response to virus;GO:0015031//protein transport gi|431921951|gb|ELK19124.1|/0/AP-1 complex subunit mu-1 [Pteropus alecto] 27058 1388 26.64333333 26.90333333 0.014010346 Up 0.100643123 Srp9 signal recognition particle 9 K03109|1|2e-42|175|mmu:27058|signal recognition particle subunit SRP9 GO:0048500//signal recognition particle;GO:0030867//rough endoplasmic reticulum membrane GO:0003723//RNA binding;GO:0043021//ribonucleoprotein complex binding GO:0006414//translational elongation;GO:0006613//cotranslational protein targeting to membrane gi|6755662|ref|NP_036188.1|/2.0292e-41/signal recognition particle 9 kDa protein [Mus musculus] 19047 2379 56.67333333 56.41666667 -0.006548631 Down 0.100643123 Ppp1cc "protein phosphatase 1, catalytic subunit, gamma isoform" K06269|1|0.0|672|bacu:103017316|serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] GO:0031966//mitochondrial membrane;GO:0008287//protein serine/threonine phosphatase complex;GO:0032155;GO:0030425//dendrite;GO:0000776//kinetochore;GO:0035097//histone methyltransferase complex;GO:0016604//nuclear body GO:0004721//phosphoprotein phosphatase activity;GO:0043169//cation binding;GO:0019900//kinase binding GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006913//nucleocytoplasmic transport;GO:0006073//cellular glucan metabolic process;GO:0007067//mitotic nuclear division;GO:0030154//cell differentiation;GO:0006464//cellular protein modification process;GO:0006641//triglyceride metabolic process;GO:0048646//anatomical structure formation involved in morphogenesis gi|744611726|ref|XP_010994159.1|/0/PREDICTED: serine/threonine-protein phosphatase PP1-gamma catalytic subunit [Camelus dromedarius] 224105 5741 6.823333333 6.75 -0.015589194 Down 0.100614916 Pak2 p21 protein (Cdc42/Rac)-activated kinase 2 K04410|1|0.0|960|rno:100910732|p21-activated kinase 2 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0032550;GO:0030295//protein kinase activator activity;GO:0004672//protein kinase activity;GO:0019900//kinase binding GO:0040007//growth;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045860//positive regulation of protein kinase activity;GO:0097191//extrinsic apoptotic signaling pathway gi|532000789|ref|XP_005344887.1|/0/PREDICTED: serine/threonine-protein kinase PAK 2 [Microtus ochrogaster] 20397 4100.81 6.583333333 6.51 -0.016160704 Down 0.100614916 Sgpl1 sphingosine phosphate lyase 1 K01634|1|0.0|1126|mmu:20397|sphinganine-1-phosphate aldolase [EC:4.1.2.27] - - - - 50996 2471 5.836666667 5.91 0.018013452 Up 0.100614916 Pdcd7 programmed cell death 7 - - - GO:0012502//induction of programmed cell death;GO:0031960//response to corticosteroid gi|148271093|ref|NP_057897.2|/1.17757e-99/programmed cell death protein 7 [Mus musculus] 224024 3356 4.016666667 3.95 -0.024146087 Down 0.100614916 Scarf2 "scavenger receptor class F, member 2" K06709|1|2e-63|246|crg:105346814|jumonji domain-containing protein 2 [EC:1.14.11.-] - - - - 217344 3713 5.283333333 5.353333333 0.018989052 Up 0.100614916 Rhbdf2 rhomboid 5 homolog 2 K02857|1|8e-10|69.3|aec:105149114|rhomboid-related protein 1/2/3 [EC:3.4.21.105] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0004175//endopeptidase activity;GO:0005515//protein binding GO:0009306//protein secretion;GO:0019538//protein metabolic process;GO:0009306//protein secretion;GO:0019538//protein metabolic process gi|264681541|ref|NP_766160.2|/0/inactive rhomboid protein 2 [Mus musculus] 18223 2733 4.59 4.663333333 0.022867403 Up 0.100614916 Numbl numb-like K06057|1|0.0|901|ggo:101149149|numb GO:0044424 - GO:0021846//cell proliferation in forebrain;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0031346//positive regulation of cell projection organization;GO:0045216//cell-cell junction organization;GO:0010720//positive regulation of cell development;GO:0043170;GO:0007166//cell surface receptor signaling pathway;GO:0021537//telencephalon development gi|426388801|ref|XP_004060821.1|/0/PREDICTED: numb-like protein [Gorilla gorilla gorilla] 108687 2294 4.89 4.823333333 -0.019803949 Down 0.100614916 Edem2 "ER degradation enhancer, mannosidase alpha-like 2" "K10085|1|0.0|1086|mmu:108687|ER degradation enhancer, mannosidase alpha-like 2" - GO:0046872//metal ion binding;GO:0015924//mannosyl-oligosaccharide mannosidase activity - gi|254540029|ref|NP_663512.2|/0/ER degradation-enhancing alpha-mannosidase-like protein 2 precursor [Mus musculus] 328949 7843 4 4.066666667 0.023846742 Up 0.100614916 Mcc mutated in colorectal cancers - GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0046872//metal ion binding;GO:0005488//binding GO:0010631//epithelial cell migration;GO:0030178//negative regulation of Wnt signaling pathway;GO:0008285//negative regulation of cell proliferation gi|145699114|ref|NP_001078842.1|/0/colorectal mutant cancer protein isoform 1 [Mus musculus] 433864 3542 5.8 5.87 0.017307603 Up 0.100614916 Nom1 nucleolar protein with MIF4G domain 1 K17583|1|0.0|1368|mmu:433864|nucleolar MIF4G domain-containing protein 1 - - - gi|134288861|ref|NP_001028629.2|/0/nucleolar MIF4G domain-containing protein 1 [Mus musculus] 66861 4054 6.92 6.993333333 0.015208234 Up 0.100614916 Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 K09530|1|0.0|1623|mmu:66861|DnaJ homolog subfamily C member 10 - - - - 239559 2132.19 5.073333333 5.006666667 -0.019083546 Down 0.100614916 A4galt "alpha 1,4-galactosyltransferase" K01988|1|0.0|690|mmu:239559|lactosylceramide 4-alpha-galactosyltransferase [EC:2.4.1.228] GO:0044431//Golgi apparatus part;GO:0031224//intrinsic component of membrane;GO:0044431//Golgi apparatus part;GO:0031224//intrinsic component of membrane GO:0035250//UDP-galactosyltransferase activity;GO:0035250//UDP-galactosyltransferase activity GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process gi|564361254|ref|XP_006242177.1|/0/PREDICTED: lactosylceramide 4-alpha-galactosyltransferase isoform X2 [Rattus norvegicus] 234736 4443 5.61 5.676666667 0.017043258 Up 0.100614916 Rfwd3 ring finger and WD repeat domain 3 K15691|1|0.0|1515|mmu:234736|E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0019787//ubiquitin-like protein transferase activity GO:0006259//DNA metabolic process;GO:0009314//response to radiation;GO:0044773//mitotic DNA damage checkpoint;GO:0032446//protein modification by small protein conjugation gi|31542200|ref|NP_666330.2|/0/E3 ubiquitin-protein ligase RFWD3 [Mus musculus] 12168 11094 4.51 4.436666667 -0.023651268 Down 0.100614916 Bmpr2 "bone morphogenetic protein receptor, type II (serine/threonine kinase)" K04671|1|0.0|1863|mmu:12168|bone morphogenetic protein receptor type-2 [EC:2.7.11.30] GO:0043005//neuron projection;GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane;GO:0044424;GO:0044297//cell body GO:0004675//transmembrane receptor protein serine/threonine kinase activity;GO:0032550;GO:0005515//protein binding;GO:0043169//cation binding GO:0001935//endothelial cell proliferation;GO:0001704//formation of primary germ layer;GO:0019229//regulation of vasoconstriction;GO:0030282//bone mineralization;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001945//lymph vessel development;GO:0016049//cell growth;GO:0051053//negative regulation of DNA metabolic process;GO:0001934//positive regulation of protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0048771//tissue remodeling;GO:0001649//osteoblast differentiation;GO:0003073//regulation of systemic arterial blood pressure;GO:0010594//regulation of endothelial cell migration;GO:0043010//camera-type eye development;GO:0007417//central nervous system development;GO:0033554//cellular response to stress;GO:0010631//epithelial cell migration;GO:0003002//regionalization;GO:0001568//blood vessel development;GO:0030324//lung development gi|6680804|ref|NP_031587.1|/0/bone morphogenetic protein receptor type-2 precursor [Mus musculus] 14590 1340 5.786666667 5.856666667 0.017347244 Up 0.100614916 Ggh gamma-glutamyl hydrolase K01307|1|8e-173|608|mmu:14590|gamma-glutamyl hydrolase [EC:3.4.19.9] - - - - 58230 2096 4.463333333 4.396666667 -0.021711396 Down 0.100614916 Rnf8 ring finger protein 8 K10667|1|0.0|901|mmu:58230|E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0042802//identical protein binding;GO:0019787//ubiquitin-like protein transferase activity GO:0000209//protein polyubiquitination;GO:0000726;GO:0033522//histone H2A ubiquitination;GO:0034728//nucleosome organization;GO:0006414//translational elongation;GO:0007281//germ cell development;GO:0009314//response to radiation;GO:0019941//modification-dependent protein catabolic process;GO:0000087//mitotic M phase;GO:0002204//somatic recombination of immunoglobulin genes involved in immune response gi|50510567|dbj|BAD32269.1|/0/mKIAA0646 protein [Mus musculus] 70561 4060.48 5.273333333 5.34 0.018124548 Up 0.100614916 Txndc16 thioredoxin domain containing 16 "K18042|1|0.0|743|mgp:100543409|serine/threonine/tyrosine-interacting protein;K08056|2|6e-09|66.6|xtr:394954|protein disulfide isomerase family A, member 3 [EC:5.3.4.1]" - - GO:0019725//cellular homeostasis;GO:0019725//cellular homeostasis gi|50510891|dbj|BAD32431.1|/0/mKIAA1344 protein [Mus musculus] 209456 4377 4.316666667 4.386666667 0.023207391 Up 0.100614916 Trp53bp2 transformation related protein 53 binding protein 2 K16823|1|0.0|2024|mmu:209456|apoptosis-stimulating of p53 protein 2 - - - gi|112799851|ref|NP_775554.2|/0/apoptosis-stimulating of p53 protein 2 [Mus musculus] 71972 5786.43 4.09 4.02 -0.024905342 Down 0.100614916 Dnmbp dynamin binding protein "K12365|1|2e-20|105|amj:102575045|phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein" GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005488//binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005488//binding GO:0007266//Rho protein signal transduction;GO:0007266//Rho protein signal transduction gi|36796741|ref|NP_082305.1|/0/dynamin-binding protein isoform 1 [Mus musculus] 68023 1547 29.75 29.50333333 -0.012011707 Down 0.100577306 Pdf peptide deformylase (mitochondrial) K01462|1|4e-122|441|mmu:68023|peptide deformylase [EC:3.5.1.88] - - - "gi|255003823|ref|NP_080789.2|/3.0074e-121/peptide deformylase, mitochondrial [Mus musculus]" 106264 1471 30.27666667 30.53 0.01202121 Up 0.100577306 0610012G03Rik RIKEN cDNA 0610012G03 gene - - - - gi|74222238|dbj|BAE26926.1|/8.68663e-38/unnamed protein product [Mus musculus] 51810 3670 37.16 36.91 -0.009738764 Down 0.100577306 Hnrnpu heterogeneous nuclear ribonucleoprotein U K12888|1|0.0|899|mmu:51810|heterogeneous nuclear ribonucleoprotein U GO:0043234//protein complex;GO:0005681//spliceosomal complex GO:0032550;GO:0003676//nucleic acid binding GO:0006396//RNA processing;GO:0048255//mRNA stabilization;GO:0051234//establishment of localization "gi|148681230|gb|EDL13177.1|/0/heterogeneous nuclear ribonucleoprotein U, isoform CRA_b [Mus musculus]" 20216 2557 0.176666667 0.193333333 0.130060541 Up 0.100549099 Acsm3 acyl-CoA synthetase medium-chain family member 3 K01896|1|0.0|1195|mmu:20216|medium-chain acyl-CoA synthetase [EC:6.2.1.2] GO:0044429;GO:0044429;GO:0044429 GO:0043169//cation binding;GO:0032550;GO:0016878//acid-thiol ligase activity;GO:0043169//cation binding;GO:0032550;GO:0016878//acid-thiol ligase activity;GO:0043169//cation binding;GO:0032550;GO:0016878//acid-thiol ligase activity GO:0006631//fatty acid metabolic process;GO:0006631//fatty acid metabolic process;GO:0006631//fatty acid metabolic process "gi|148685235|gb|EDL17182.1|/0/acyl-CoA synthetase medium-chain family member 3, isoform CRA_b, partial [Mus musculus]" 11784 3283 0.276666667 0.253333333 -0.127111918 Down 0.100549099 Apba2 "amyloid beta (A4) precursor protein-binding, family A, member 2" K20055|1|0.0|1432|mmu:11784|amyloid beta A4 precursor protein-binding family A member 2 GO:0016020//membrane;GO:0016020//membrane GO:0043168//anion binding;GO:0043168//anion binding GO:0007267//cell-cell signaling;GO:0045184//establishment of protein localization;GO:0043009//chordate embryonic development;GO:0040007//growth;GO:0006887//exocytosis;GO:0044708//single-organism behavior;GO:0010467//gene expression;GO:0007267//cell-cell signaling;GO:0045184//establishment of protein localization;GO:0043009//chordate embryonic development;GO:0040007//growth;GO:0006887//exocytosis;GO:0044708//single-organism behavior;GO:0010467//gene expression gi|39930317|ref|NP_031487.1|/0/amyloid beta A4 precursor protein-binding family A member 2 [Mus musculus] 16364 4683 0.216666667 0.236666667 0.127379306 Up 0.100549099 Irf4 interferon regulatory factor 4 K09445|1|0.0|960|mmu:16364|interferon regulatory factor 4 GO:0043231//intracellular membrane-bounded organelle GO:0008276//protein methyltransferase activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001067 GO:0051099//positive regulation of binding;GO:0006366//transcription from RNA polymerase II promoter;GO:0042091;GO:0001562//response to protozoan;GO:0042097;GO:0008213;GO:0002295//T-helper cell lineage commitment;GO:0002224//toll-like receptor signaling pathway;GO:0042094//interleukin-2 biosynthetic process;GO:0001773//myeloid dendritic cell activation;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0016573//histone acetylation "gi|148700431|gb|EDL32378.1|/0/interferon regulatory factor 4, isoform CRA_a, partial [Mus musculus]" 633947 1700 0.176666667 0.193333333 0.130060541 Up 0.100549099 Gm6225 predicted gene 6225 - - - - gi|74177823|dbj|BAE39001.1|/2.41459e-42/unnamed protein product [Mus musculus] 12289 8701 0.173333333 0.19 0.132450296 Up 0.100549099 Cacna1d "calcium channel, voltage-dependent, L type, alpha 1D subunit" K04851|1|0.0|3768|cge:100772497|voltage-dependent calcium channel L type alpha-1D GO:0034704//calcium channel complex GO:0005262//calcium channel activity GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport gi|134288900|ref|NP_083257.2|/0/voltage-dependent L-type calcium channel subunit alpha-1D isoform 1 [Mus musculus] 18726 2281 0.183333333 0.2 0.125530882 Up 0.100549099 Lilra6 "leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6" K06512|1|0.0|893|mmu:18726|leukocyte immunoglobulin-like receptor - - - - 271375 1750 0.2 0.183333333 -0.125530882 Down 0.100549099 Cd200r2 Cd200 receptor 2 K06531|1|9e-11|71.2|tru:101078311|poliovirus receptor-related protein 2;K11290|2|2e-09|54.7|rno:317165|template-activating factor I GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0005488//binding - gi|45504373|ref|NP_996258.1|/1.69633e-131/cell surface glycoprotein CD200 receptor 2 precursor [Mus musculus] 66240 1446 0.173333333 0.19 0.132450296 Up 0.100549099 Kcne1l "potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene" K04895|1|1e-56|223|mmu:66240|potassium voltage-gated channel Isk-related subfamily E member 1-like GO:0031224//intrinsic component of membrane - GO:0044765//single-organism transport gi|26380608|dbj|BAC25441.1|/5.66561e-82/unnamed protein product [Mus musculus] 228598 2687 0.2 0.183333333 -0.125530882 Down 0.100549099 Ebf4 early B cell factor 4 K09103|1|0.0|1055|mmu:228598|early B-cell factor GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0005515//protein binding "GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|160333394|ref|NP_001103983.1|/0/transcription factor COE4 [Mus musculus] 78134 4237 0.186666667 0.17 -0.13492958 Down 0.100549099 Lpar4 lysophosphatidic acid receptor 4 K04275|1|0.0|742|lve:103078023|lysophosphatidic acid receptor 4 GO:0031224//intrinsic component of membrane GO:0001608;GO:0005488//binding GO:0035588 gi|602708252|ref|XP_007464390.1|/0/PREDICTED: lysophosphatidic acid receptor 4 isoform X1 [Lipotes vexillifer] 77583 2020 0.17 0.186666667 0.13492958 Up 0.100549099 Notum notum pectinacetylesterase homolog (Drosophila) K19882|1|0.0|904|mmu:77583|O-palmitoleoyl-L-serine hydrolase [EC:3.1.1.98] - - - gi|148702837|gb|EDL34784.1|/0/mCG2125 [Mus musculus] 70713 2444 0.686666667 0.716666667 0.061692322 Up 0.100464478 Gpr137c G protein-coupled receptor 137C - - - - gi|198278421|ref|NP_081794.2|/9.63204e-171/integral membrane protein GPR137C [Mus musculus] 12014 8493 0.68 0.71 0.062284278 Up 0.100464478 Bach2 "BTB and CNC homology, basic leucine zipper transcription factor 2" K09042|1|0.0|1570|mmu:12014|transcription regulator BACH - - - - 60344 9817 0.61 0.636666667 0.06172899 Up 0.100464478 Fign fidgetin K13254|1|2e-64|251|phu:Phum_PHUM514830|spastin [EC:3.6.4.3] GO:0034399//nuclear periphery;GO:0034399//nuclear periphery;GO:0034399//nuclear periphery GO:0005515//protein binding;GO:0016462//pyrophosphatase activity;GO:0032550;GO:0005515//protein binding;GO:0016462//pyrophosphatase activity;GO:0032550;GO:0005515//protein binding;GO:0016462//pyrophosphatase activity;GO:0032550 GO:0044708//single-organism behavior;GO:0044708//single-organism behavior;GO:0044708//single-organism behavior "gi|148695049|gb|EDL26996.1|/0/fidgetin, isoform CRA_b, partial [Mus musculus]" 20877 1981 0.743333333 0.773333333 0.057081095 Up 0.100464478 Aurkb aurora kinase B K11479|1|0.0|699|mmu:20877|aurora kinase B [EC:2.7.11.1] - - - - 243897 955.67 0.65 0.623333333 -0.060435854 Down 0.100464478 Ggn gametogenetin - GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0012505//endomembrane system;GO:0031982//vesicle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen GO:0005515//protein binding;GO:0005515//protein binding GO:0044699;GO:0033036;GO:0065003;GO:0033036;GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|123173829|ref|NP_874353.2|/0/gametogenetin isoform 1 [Mus musculus] 17392 1801 0.68 0.653333333 -0.057715498 Down 0.100464478 Mmp3 matrix metallopeptidase 3 "K01394|1|0.0|956|mmu:17392|matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]" GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0031012//extracellular matrix;GO:0044421 GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0005515//protein binding GO:0016477//cell migration;GO:0043062//extracellular structure organization;GO:0044703;GO:0031668//cellular response to extracellular stimulus;GO:0043627//response to estrogen;GO:0022411;GO:0009611//response to wounding;GO:0019538//protein metabolic process;GO:0032963//collagen metabolic process;GO:0002237//response to molecule of bacterial origin;GO:0070555//response to interleukin-1;GO:0043200//response to amino acid gi|6754714|ref|NP_034939.1|/0/stromelysin-1 preproprotein [Mus musculus] 270906 3827 0.65 0.623333333 -0.060435854 Down 0.100464478 Prr11 proline rich 11 K18734|1|1e-51|207|fch:102052155|protein SMG8 - - - gi|30425358|ref|NP_780772.1|/1.09095e-142/proline-rich protein 11 [Mus musculus] 100340 1925 0.69 0.663333333 -0.056862337 Down 0.100464478 Smpdl3b "sphingomyelin phosphodiesterase, acid-like 3B" K01128|1|0.0|931|mmu:100340|sphingomyelin phosphodiesterase acid-like 3 [EC:3.1.4.-] GO:0044421 GO:0004620//phospholipase activity GO:0006684//sphingomyelin metabolic process gi|19527104|ref|NP_598649.1|/0/acid sphingomyelinase-like phosphodiesterase 3b precursor [Mus musculus] 67492 2796 0.776666667 0.743333333 -0.063286245 Down 0.100464478 Zfand4 "zinc finger, AN1-type domain 4" K12163|1|0.0|971|mmu:67492|AN1-type zinc finger and ubiquitin domain-containing protein 1 - GO:0043169//cation binding;GO:0043169//cation binding - gi|827447177|ref|NP_001296375.1|/0/AN1-type zinc finger protein 4 isoform 3 [Mus musculus] 76510 3099.36 28.90666667 28.66333333 -0.012195862 Down 0.100455075 Trappc9 trafficking protein particle complex 9 K20306|1|0.0|2267|mmu:76510|trafficking protein particle complex subunit 9 GO:0043231//intracellular membrane-bounded organelle - GO:0048869//cellular developmental process gi|257467582|ref|NP_001158115.1|/0/trafficking protein particle complex subunit 9 isoform 5 [Mus musculus] 17256 941.81 36.36333333 36.60666667 0.009621957 Up 0.100455075 Mea1 male enhanced antigen 1 - GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424 - GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|472235310|ref|NP_001264238.1|/1.26416e-78/male-enhanced antigen 1 isoform a [Mus musculus] 23828 1607 40.16666667 40.40666667 0.008594601 Up 0.100455075 Bves blood vessel epicardial substance - - - - - 54473 3705 26.99666667 26.75666667 -0.012882889 Down 0.100455075 Tollip toll interacting protein K05402|1|1e-124|451|mmu:54473|toll-interacting protein GO:0044444//cytoplasmic part;GO:0044451 GO:0044389//ubiquitin-like protein ligase binding;GO:0005102//receptor binding;GO:0044390//ubiquitin-like protein conjugating enzyme binding;GO:0032182//ubiquitin-like protein binding GO:0006952//defense response;GO:0016925//protein sumoylation;GO:0006796//phosphate-containing compound metabolic process;GO:0007154//cell communication gi|13591860|ref|NP_076253.1|/8.36672e-124/toll-interacting protein [Mus musculus] 12454 2632 25.33 25.57 0.013605084 Up 0.100455075 Ccnk cyclin K K15188|1|2e-34|150|myd:102767544|cyclin T - - - gi|990026782|ref|XP_015455074.1|/1.53011e-153/PREDICTED: cyclin-K [Pteropus alecto] 71514 2654.68 24.01666667 24.26 0.014543621 Up 0.100455075 Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) "K13219|1|2e-159|565|ngi:103733300|splicing factor, proline- and glutamine-rich" GO:0016604//nuclear body;GO:0034399//nuclear periphery GO:0003676//nucleic acid binding "GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter" "gi|148698320|gb|EDL30267.1|/1.99729e-162/mCG1050219, partial [Mus musculus]" 16004 8948 23.64333333 23.88 0.01436939 Up 0.100455075 Igf2r insulin-like growth factor 2 receptor K06564|1|0.0|4900|mmu:16004|insulin-like growth factor 2 receptor GO:0030117//membrane coat;GO:0000323//lytic vacuole;GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope;GO:0005768//endosome;GO:0005798//Golgi-associated vesicle;GO:0044421 GO:0005501//retinoid binding;GO:0005520//insulin-like growth factor binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0048029//monosaccharide binding GO:0007166//cell surface receptor signaling pathway;GO:0006915//apoptotic process;GO:0045184//establishment of protein localization;GO:0009887//organ morphogenesis;GO:0048232//male gamete generation;GO:0033993//response to lipid "gi|148670103|gb|EDL02050.1|/0/insulin-like growth factor 2 receptor, isoform CRA_b, partial [Mus musculus]" 68598 1410 52.08 51.85333333 -0.006292714 Down 0.100238821 Dnajc8 DnaJ heat shock protein family (Hsp40) member C8 K09528|1|1e-123|445|cjc:100397182|DnaJ homolog subfamily C member 8 - - - - 14661 3158 46.52666667 46.75666667 0.007114251 Up 0.100238821 Glud1 glutamate dehydrogenase 1 K00261|1|0.0|1068|mmu:14661|glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] GO:0019866//organelle inner membrane;GO:0044429 "GO:0032550;GO:0005515//protein binding;GO:0016597//amino acid binding;GO:0016639//oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor" GO:0007613//memory;GO:0050796//regulation of insulin secretion;GO:0010038//response to metal ion;GO:0006536//glutamate metabolic process "gi|6680027|ref|NP_032159.1|/0/glutamate dehydrogenase 1, mitochondrial precursor [Mus musculus]" 270210 6353 34.04666667 33.81666667 -0.009779099 Down 0.100238821 Zfp651 zinc finger protein 651 K10518|1|0.0|1300|mmu:270210|zinc finger and BTB domain-containing protein 47 - - - gi|262263345|ref|NP_001160116.1|/0/zinc finger and BTB domain-containing protein 47 [Mus musculus] 14766 3555 59.23 59.46333333 0.005672252 Up 0.100238821 Adgrg1 adhesion G protein-coupled receptor G1 K08450|1|0.0|1305|mmu:14766|G protein-coupled receptor 56 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007417//central nervous system development;GO:0022610;GO:0007186//G-protein coupled receptor signaling pathway gi|568956152|ref|XP_006530744.1|/0/PREDICTED: G-protein coupled receptor 56 isoform X3 [Mus musculus] 98193 3760 57.49666667 57.26333333 -0.005866666 Down 0.100238821 Dcaf8 DDB1 and CUL4 associated factor 8 K11804|1|0.0|1102|mmu:98193|WD repeat-containing protein 42A GO:0031461//cullin-RING ubiquitin ligase complex - - gi|23956326|ref|NP_705783.1|/0/DDB1- and CUL4-associated factor 8 [Mus musculus] 100226 2320 21.72333333 21.94666667 0.014756341 Up 0.100069578 Stx12 syntaxin 12 K13813|1|5e-127|457|mmu:100226|syntaxin 12/13 - - - gi|74204132|dbj|BAE39831.1|/3.99195e-126/unnamed protein product [Mus musculus] 53598 966 47.81666667 48.03333333 0.006522367 Up 0.100069578 Dctn3 dynactin 3 K10425|1|2e-97|357|mmu:53598|dynactin 3 "GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0044444//cytoplasmic part;GO:0000775//chromosome, centromeric region;GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0044444//cytoplasmic part;GO:0000775//chromosome, centromeric region" - GO:0000087//mitotic M phase;GO:0000087//mitotic M phase gi|227116275|ref|NP_001153037.1|/4.91707e-81/dynactin subunit 3 isoform B [Mus musculus] 27979 2966 56.09 55.87 -0.005669763 Down 0.100069578 Eif3b "eukaryotic translation initiation factor 3, subunit B" K03253|1|0.0|1448|mmu:27979|translation initiation factor 3 subunit B GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0008135//translation factor activity, RNA binding;GO:0036094//small molecule binding;GO:0005515//protein binding" GO:0006413//translational initiation gi|29789343|ref|NP_598677.1|/0/eukaryotic translation initiation factor 3 subunit B [Mus musculus] 207728 4107.16 38.01 38.23 0.008326175 Up 0.100069578 Pde2a "phosphodiesterase 2A, cGMP-stimulated" "K18283|1|0.0|1771|mmu:207728|cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]" GO:0043005//neuron projection;GO:0044425;GO:0044429;GO:0097060//synaptic membrane;GO:0043005//neuron projection;GO:0044425;GO:0044429;GO:0097060//synaptic membrane;GO:0043005//neuron projection;GO:0044425;GO:0044429;GO:0097060//synaptic membrane;GO:0043005//neuron projection;GO:0044425;GO:0044429;GO:0097060//synaptic membrane;GO:0043005//neuron projection;GO:0044425;GO:0044429;GO:0097060//synaptic membrane "GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0030551//cyclic nucleotide binding;GO:0042802//identical protein binding;GO:0019904//protein domain specific binding;GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0030551//cyclic nucleotide binding;GO:0042802//identical protein binding;GO:0019904//protein domain specific binding;GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0030551//cyclic nucleotide binding;GO:0042802//identical protein binding;GO:0019904//protein domain specific binding;GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0030551//cyclic nucleotide binding;GO:0042802//identical protein binding;GO:0019904//protein domain specific binding;GO:0043169//cation binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0030551//cyclic nucleotide binding;GO:0042802//identical protein binding;GO:0019904//protein domain specific binding;GO:0043169//cation binding" "GO:0006954//inflammatory response;GO:0071345//cellular response to cytokine stimulus;GO:0009612//response to mechanical stimulus;GO:0070305//response to cGMP;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0001885//endothelial cell development;GO:0036005;GO:0009154//purine ribonucleotide catabolic process;GO:0000060//protein import into nucleus, translocation;GO:0043114//regulation of vascular permeability;GO:0006366//transcription from RNA polymerase II promoter;GO:0071363//cellular response to growth factor stimulus;GO:0002573//myeloid leukocyte differentiation;GO:0042493//response to drug;GO:0006171//cAMP biosynthetic process;GO:0006954//inflammatory response;GO:0071345//cellular response to cytokine stimulus;GO:0009612//response to mechanical stimulus;GO:0070305//response to cGMP;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0001885//endothelial cell development;GO:0036005;GO:0009154//purine ribonucleotide catabolic process;GO:0000060//protein import into nucleus, translocation;GO:0043114//regulation of vascular permeability;GO:0006366//transcription from RNA polymerase II promoter;GO:0071363//cellular response to growth factor stimulus;GO:0002573//myeloid leukocyte differentiation;GO:0042493//response to drug;GO:0006171//cAMP biosynthetic process;GO:0006954//inflammatory response;GO:0071345//cellular response to cytokine stimulus;GO:0009612//response to mechanical stimulus;GO:0070305//response to cGMP;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0001885//endothelial cell development;GO:0036005;GO:0009154//purine ribonucleotide catabolic process;GO:0000060//protein import into nucleus, translocation;GO:0043114//regulation of vascular permeability;GO:0006366//transcription from RNA polymerase II promoter;GO:0071363//cellular response to growth factor stimulus;GO:0002573//myeloid leukocyte differentiation;GO:0042493//response to drug;GO:0006171//cAMP biosynthetic process;GO:0006954//inflammatory response;GO:0071345//cellular response to cytokine stimulus;GO:0009612//response to mechanical stimulus;GO:0070305//response to cGMP;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0001885//endothelial cell development;GO:0036005;GO:0009154//purine ribonucleotide catabolic process;GO:0000060//protein import into nucleus, translocation;GO:0043114//regulation of vascular permeability;GO:0006366//transcription from RNA polymerase II promoter;GO:0071363//cellular response to growth factor stimulus;GO:0002573//myeloid leukocyte differentiation;GO:0042493//response to drug;GO:0006171//cAMP biosynthetic process;GO:0006954//inflammatory response;GO:0071345//cellular response to cytokine stimulus;GO:0009612//response to mechanical stimulus;GO:0070305//response to cGMP;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0001885//endothelial cell development;GO:0036005;GO:0009154//purine ribonucleotide catabolic process;GO:0000060//protein import into nucleus, translocation;GO:0043114//regulation of vascular permeability;GO:0006366//transcription from RNA polymerase II promoter;GO:0071363//cellular response to growth factor stimulus;GO:0002573//myeloid leukocyte differentiation;GO:0042493//response to drug;GO:0006171//cAMP biosynthetic process" "gi|344217719|ref|NP_001230687.1|/0/cGMP-dependent 3',5'-cyclic phosphodiesterase isoform 5 [Mus musculus]" 22652 2565 0.21 0.193333333 -0.119298928 Down 0.099806311 Mkrn3 "makorin, ring finger protein, 3" K15687|1|0.0|880|mmu:22652|E3 ubiquitin-protein ligase makorin [EC:2.3.2.27] GO:0032991//macromolecular complex GO:0046914//transition metal ion binding;GO:0003824//catalytic activity - gi|61675708|ref|NP_035876.2|/0/probable E3 ubiquitin-protein ligase makorin-3 [Mus musculus] 227632 6002 0.19 0.206666667 0.121306296 Up 0.099806311 Kcnt1 "potassium channel, subfamily T, member 1" K04946|1|0.0|2315|mmu:227632|potassium channel subfamily T member 1 GO:0031224//intrinsic component of membrane GO:0005267//potassium channel activity GO:0030001//metal ion transport gi|73611942|ref|NP_780671.2|/0/potassium channel subfamily T member 1 isoform 1 [Mus musculus] 69034 645 0.246666667 0.226666667 -0.121990524 Down 0.099806311 Nupr1l nuclear protein transcriptional regulator 1 like "K15626|1|1e-08|61.6|cmk:103188442|nuclear protein, 1" - - - gi|12840957|dbj|BAB25026.1|/5.35979e-48/unnamed protein product [Mus musculus] 15227 2425 0.223333333 0.243333333 0.123735368 Up 0.099806311 Foxf1 forkhead box F1 K09399|1|8e-170|600|rno:687536|forkhead box protein F - - - gi|564321593|ref|XP_001079002.3|/6.84031e-169/PREDICTED: forkhead box protein F1 isoform X1 [Rattus norvegicus] 93732 2448 0.253333333 0.233333333 -0.118644496 Down 0.099806311 Acox2 "acyl-Coenzyme A oxidase 2, branched chain" "K10214|1|0.0|1389|mmu:93732|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase [EC:1.17.99.3]" GO:0042579//microbody;GO:0042579//microbody "GO:0008289//lipid binding;GO:0016725;GO:0005515//protein binding;GO:0016634//oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor;GO:0000166//nucleotide binding;GO:0008289//lipid binding;GO:0016725;GO:0005515//protein binding;GO:0016634//oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor;GO:0000166//nucleotide binding" GO:0009062//fatty acid catabolic process;GO:0009062//fatty acid catabolic process "gi|148688641|gb|EDL20588.1|/0/acyl-Coenzyme A oxidase 2, branched chain, isoform CRA_c, partial [Mus musculus]" 27643 2328.8 43.56 43.35333333 -0.006861031 Down 0.099759299 Ubl4a ubiquitin-like 4A K00036|1|2e-29|133|bacu:103016715|glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] GO:0072379;GO:0072379 - GO:0051234//establishment of localization;GO:0045048//protein insertion into ER membrane;GO:0051234//establishment of localization;GO:0045048//protein insertion into ER membrane gi|51773475|emb|CAF25307.1|/6.94899e-78/ubiquitin-like protein GDX [Mus musculus] 12391 1172 48.31 48.52333333 0.006356808 Up 0.099759299 Cav3 caveolin 3 K12959|1|2e-85|318|mmu:12391|caveolin 3 GO:0031224//intrinsic component of membrane;GO:0005783//endoplasmic reticulum;GO:0043234//protein complex;GO:0012505//endomembrane system;GO:0044459;GO:0042383//sarcolemma;GO:0045202//synapse;GO:0031674//I band GO:0015631//tubulin binding;GO:0019899//enzyme binding;GO:0016247//channel regulator activity GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0003206//cardiac chamber morphogenesis;GO:0032769//negative regulation of monooxygenase activity;GO:0006639//acylglycerol metabolic process;GO:0002028//regulation of sodium ion transport;GO:0003009//skeletal muscle contraction;GO:0043405//regulation of MAP kinase activity;GO:0007009//plasma membrane organization;GO:0055092//sterol homeostasis;GO:0008016//regulation of heart contraction;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0001933//negative regulation of protein phosphorylation;GO:0010469//regulation of receptor activity;GO:0045214//sarcomere organization;GO:0010830//regulation of myotube differentiation;GO:0040007//growth;GO:0032872//regulation of stress-activated MAPK cascade;GO:0033500//carbohydrate homeostasis;GO:0031112;GO:0032412//regulation of ion transmembrane transporter activity;GO:0000768//syncytium formation by plasma membrane fusion;GO:0006942//regulation of striated muscle contraction;GO:0008361//regulation of cell size;GO:0003254//regulation of membrane depolarization;GO:0060306//regulation of membrane repolarization;GO:0008283//cell proliferation;GO:0001765//membrane raft assembly;GO:0016192//vesicle-mediated transport;GO:0090150//establishment of protein localization to membrane;GO:0006816//calcium ion transport;GO:0051640//organelle localization;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0060444//branching involved in mammary gland duct morphogenesis gi|635120445|ref|XP_007983286.1|/2.44007e-88/PREDICTED: caveolin-3 [Chlorocebus sabaeus] 239706 1347 27.55 27.76333333 0.011128473 Up 0.099759299 Mettl22 methyltransferase like 22 K17536|1|5e-39|164|shr:100930168|connector enhancer of kinase suppressor of Ras 2;K00884|2|5e-06|55.1|bmy:Bm1_35310|N-acetylglucosamine kinase [EC:2.7.1.59] - GO:0016741 GO:0008152//metabolic process gi|22122829|ref|NP_666359.1|/0/methyltransferase-like protein 22 [Mus musculus] 50493 3366.65 20.25 20.45666667 0.014649175 Up 0.099759299 Txnrd1 thioredoxin reductase 1 K00384|1|0.0|997|mmu:50493|thioredoxin reductase (NADPH) [EC:1.8.1.9] GO:0031981//nuclear lumen;GO:0044297//cell body;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body;GO:0044444//cytoplasmic part "GO:0046914//transition metal ion binding;GO:0000166//nucleotide binding;GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor;GO:0042802//identical protein binding;GO:0016209//antioxidant activity;GO:0046914//transition metal ion binding;GO:0000166//nucleotide binding;GO:0050664//oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor;GO:0042802//identical protein binding;GO:0016209//antioxidant activity" GO:0009611//response to wounding;GO:0042743//hydrogen peroxide metabolic process;GO:0018941;GO:0051259//protein oligomerization;GO:0046688//response to copper ion;GO:0019725//cellular homeostasis;GO:0006790//sulfur compound metabolic process;GO:0001887//selenium compound metabolic process;GO:0044281//small molecule metabolic process;GO:0008219//cell death;GO:0006725//cellular aromatic compound metabolic process;GO:0055114//oxidation-reduction process;GO:0033554//cellular response to stress;GO:0001704//formation of primary germ layer;GO:0042743//hydrogen peroxide metabolic process;GO:0051259//protein oligomerization;GO:0019725//cellular homeostasis;GO:0001887//selenium compound metabolic process;GO:0008219//cell death;GO:0006725//cellular aromatic compound metabolic process;GO:0006950//response to stress;GO:0055114//oxidation-reduction process;GO:0048598//embryonic morphogenesis "gi|110224447|ref|NP_001035988.1|/0/thioredoxin reductase 1, cytoplasmic isoform 1 [Mus musculus]" 72972 5716.02 20.71666667 20.91333333 0.013631138 Up 0.099561849 Ccser2 coiled-coil serine rich 2 - GO:0005856//cytoskeleton;GO:0005856//cytoskeleton GO:0015631//tubulin binding;GO:0015631//tubulin binding - gi|80861474|ref|NP_081321.1|/0/serine-rich coiled-coil domain-containing protein 2 isoform 1 [Mus musculus] 229279 3968.84 23.13333333 23.33666667 0.012625344 Up 0.099561849 Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 K12741|1|3e-106|389|pale:102891644|heterogeneous nuclear ribonucleoprotein A1/A3 GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0042995//cell projection;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0042995//cell projection;GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0042995//cell projection GO:0003723//RNA binding;GO:0051032;GO:0036094//small molecule binding;GO:0003723//RNA binding;GO:0051032;GO:0036094//small molecule binding;GO:0003723//RNA binding;GO:0051032;GO:0036094//small molecule binding GO:0050658//RNA transport;GO:0000377;GO:0050658//RNA transport;GO:0000377;GO:0006396//RNA processing;GO:0050658//RNA transport gi|585645604|ref|XP_006882199.1|/8.37577e-109/PREDICTED: heterogeneous nuclear ribonucleoprotein A3-like [Elephantulus edwardii] 11771 3416.33 37.77333333 37.97333333 0.007618545 Up 0.099561849 Ap2a1 "adaptor-related protein complex 2, alpha 1 subunit" K11824|1|0.0|1733|mmu:11771|AP-2 complex subunit alpha "GO:0012505//endomembrane system;GO:0044459;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0030119//AP-type membrane coat adaptor complex;GO:0012505//endomembrane system;GO:0044459;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0030119//AP-type membrane coat adaptor complex" GO:0005515//protein binding;GO:0022892//substrate-specific transporter activity;GO:0005515//protein binding;GO:0022892//substrate-specific transporter activity GO:0016192//vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0015031//protein transport "gi|148690825|gb|EDL22772.1|/0/adaptor protein complex AP-2, alpha 1 subunit, partial [Mus musculus]" 53605 2042.38 41.76333333 41.95666667 0.0066632 Up 0.099345594 Nap1l1 nucleosome assembly protein 1-like 1 K11279|1|5e-119|432|ocu:100346784|nucleosome assembly protein 1-like 1 - - - gi|226443026|ref|NP_001140179.1|/1.12418e-120/nucleosome assembly protein 1-like 1 isoform 1 precursor [Mus musculus] 217124 4345 27.14666667 27.34 0.010238182 Up 0.099345594 Ppp1r9b "protein phosphatase 1, regulatory subunit 9B" K17551|1|0.0|1199|mmu:217124|neurabin GO:0031981//nuclear lumen;GO:0016020//membrane;GO:0070161;GO:0015629//actin cytoskeleton;GO:0008287//protein serine/threonine phosphatase complex;GO:0030425//dendrite;GO:0001726//ruffle GO:0008092//cytoskeletal protein binding;GO:0019903//protein phosphatase binding;GO:0019212//phosphatase inhibitor activity GO:0001558//regulation of cell growth;GO:0008283//cell proliferation;GO:0031175//neuron projection development;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0006396//RNA processing;GO:0043278//response to morphine;GO:0006468//protein phosphorylation;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0030031//cell projection assembly;GO:0022402//cell cycle process;GO:0007346//regulation of mitotic cell cycle;GO:0019932//second-messenger-mediated signaling gi|50053703|ref|NP_758465.2|/0/neurabin-2 [Mus musculus] 13726 1601 28.73333333 28.92 0.009342184 Up 0.099345594 Emd emerin K12569|1|2e-110|402|mmu:13726|emerin GO:0034399//nuclear periphery;GO:0031965//nuclear membrane;GO:0015630//microtubule cytoskeleton;GO:0031224//intrinsic component of membrane;GO:0019866//organelle inner membrane GO:0015631//tubulin binding GO:0070848//response to growth factor;GO:0006998//nuclear envelope organization;GO:0006611//protein export from nucleus;GO:0008285//negative regulation of cell proliferation;GO:0030111//regulation of Wnt signaling pathway;GO:0007519//skeletal muscle tissue development;GO:0035411//catenin import into nucleus gi|6679641|ref|NP_031953.1|/1.62387e-109/emerin [Mus musculus] 12933 2968 0.263333333 0.283333333 0.105610188 Up 0.099176351 Crmp1 collapsin response mediator protein 1 K07528|1|0.0|847|phi:102107688|dihydropyrimidinase-like 2 GO:0015630//microtubule cytoskeleton;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043227//membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0043005//neuron projection;GO:0044297//cell body;GO:0043227//membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0005515//protein binding;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0005515//protein binding" GO:0048731//system development;GO:0006935//chemotaxis;GO:0006206//pyrimidine nucleobase metabolic process;GO:0006935//chemotaxis;GO:0006206//pyrimidine nucleobase metabolic process;GO:0030182//neuron differentiation gi|40068507|ref|NP_031791.3|/0/dihydropyrimidinase-related protein 1 isoform 2 [Mus musculus] 73430 5159 0.313333333 0.29 -0.111645356 Down 0.099176351 1700049G17Rik zinc finger protein 974 K09228|1|0.0|1213|mmu:338354|KRAB domain-containing zinc finger protein - - - gi|223462786|gb|AAI41374.1|/0/1700049G17Rik protein [Mus musculus] 234889 13727 0.253333333 0.273333333 0.109624491 Up 0.099176351 Gucy1a2 "guanylate cyclase 1, soluble, alpha 2" K12318|1|0.0|1300|mmu:234889|guanylate cyclase soluble subunit alpha [EC:4.6.1.2] - - - - 19158 2527 21.87 22.05333333 0.012043513 Up 0.099166949 Cyth2 cytohesin 2 K18441|1|0.0|876|chx:102183630|cytohesin GO:0016020//membrane;GO:0044424 GO:0008289//lipid binding GO:0007155//cell adhesion;GO:0032011//ARF protein signal transduction gi|829994740|ref|XP_012609820.1|/0/PREDICTED: cytohesin-2 isoform X1 [Microcebus murinus] 76302 2300 18.93666667 18.75333333 -0.01403535 Down 0.099166949 Pcnp PEST proteolytic signal containing nuclear protein - GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0006511//ubiquitin-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation gi|984086452|ref|XP_015334054.1|/1.382e-62/PREDICTED: PEST proteolytic signal-containing nuclear protein isoform X1 [Marmota marmota marmota] 68041 2056.41 34.24666667 34.42666667 0.007562927 Up 0.099166949 Mid1ip1 Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) - - - - - 241296 4254 41.21 41.03333333 -0.006198108 Down 0.099166949 Lrrc8a leucine rich repeat containing 8A K16175|1|1e-29|135|cin:100183941|protein scribble;K19613|5|2e-28|131|bfo:BRAFLDRAFT_214464|leucine-rich repeat protein SHOC2 GO:0031224//intrinsic component of membrane - GO:0002327//immature B cell differentiation gi|29244192|ref|NP_808393.1|/0/volume-regulated anion channel subunit LRRC8A [Mus musculus] 76832 1643 0.93 0.896666667 -0.052658949 Down 0.09909173 Hyls1 hydrolethalus syndrome 1 K16472|1|2e-168|594|mmu:76832|hydrolethalus syndrome protein 1 GO:0005815//microtubule organizing center - - gi|227499246|ref|NP_084038.1|/1.76892e-167/hydrolethalus syndrome protein 1 homolog [Mus musculus] 414116 586 0.883333333 0.853333333 -0.049848549 Down 0.09909173 D630024D03Rik RIKEN cDNA D630024D03 gene - - - - "gi|148691830|gb|EDL23777.1|/9.81831e-36/mCG144732, partial [Mus musculus]" 212153 3643 0.91 0.94 0.046794211 Up 0.09909173 Ccdc191 coiled-coil domain containing 191 K11423|1|4e-08|63.5|dgr:Dgri_GH16034|histone-lysine N-methyltransferase SETD2 [EC:2.1.1.43];K16807|2|4e-08|63.5|clv:102086090|MAP7 domain-containing protein 3 - - - - 332579 1611 0.986666667 1.02 0.047934477 Up 0.09909173 Card9 "caspase recruitment domain family, member 9" K12794|1|0.0|1018|mmu:332579|caspase recruitment domain-containing protein 9 GO:0044424 GO:0019904//protein domain specific binding;GO:0042802//identical protein binding GO:0032872//regulation of stress-activated MAPK cascade;GO:0032675//regulation of interleukin-6 production;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0042742//defense response to bacterium;GO:1901652//response to peptide;GO:0006915//apoptotic process;GO:0032663;GO:0007254//JNK cascade;GO:0001819//positive regulation of cytokine production;GO:0002252;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0031349//positive regulation of defense response;GO:0043331//response to dsRNA;GO:0002237//response to molecule of bacterial origin;GO:0032680//regulation of tumor necrosis factor production gi|147904864|ref|NP_001032836.1|/0/caspase recruitment domain-containing protein 9 [Mus musculus] 16469 5529 0.83 0.856666667 0.045622617 Up 0.09909173 Jrk jerky K09229|1|3e-55|221|acs:100561333|KRAB and SCAN domains-containing zinc finger protein;K19326|2|3e-50|204|lcm:102349340|nesprin-1;K05164|3|4e-45|187|lcm:102357679|interleukin 17 receptor;K11496|4|5e-19|100|oaa:100077513|centromere protein B - - - - 212898 4243 1.083333333 1.05 -0.04508789 Down 0.09909173 Dse dermatan sulfate epimerase K01794|1|0.0|1887|mmu:212898|chondroitin-glucuronate 5-epimerase [EC:5.1.3.19] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives" GO:0006024//glycosaminoglycan biosynthetic process gi|74142284|dbj|BAE31905.1|/0/unnamed protein product [Mus musculus] 241627 4246 0.896666667 0.926666667 0.04747871 Up 0.09909173 Wdr76 WD repeat domain 76 K10140|1|1e-11|75.5|gja:107123208|DNA damage-binding protein 2 - - - gi|206558258|sp|A6PWY4.1|WDR76_MOUSE/0/RecName: Full=WD repeat-containing protein 76 72568 3176.16 0.866666667 0.836666667 -0.050824259 Down 0.09909173 Lin9 lin-9 homolog (C. elegans) - - - - gi|636526391|ref|NP_001096652.2|/0/protein lin-9 homolog [Mus musculus] 67607 3833 0.983333333 1.016666667 0.048094288 Up 0.09909173 Zfp788 zinc finger protein 788 K09228|1|0.0|1806|mmu:67607|KRAB domain-containing zinc finger protein - - - gi|148680492|gb|EDL12439.1|/0/RIKEN cDNA 2810426N06 [Mus musculus] 78937 6691 0.72 0.693333333 -0.054447784 Down 0.09909173 Avl9 AVL9 homolog (S. cerevisiase) - GO:0031224//intrinsic component of membrane;GO:0005768//endosome - GO:0048870//cell motility gi|28972113|dbj|BAC65510.1|/0/mKIAA0241 protein [Mus musculus] 20744 16348 0.703333333 0.73 0.053687871 Up 0.09909173 Strbp spermatid perinuclear RNA binding protein K13200|1|0.0|1193|mmu:20744|spermatid perinuclear RNA-binding protein GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding GO:0009612//response to mechanical stimulus;GO:0007281//germ cell development;GO:0048232//male gamete generation gi|114842377|ref|NP_033287.2|/0/spermatid perinuclear RNA-binding protein [Mus musculus] 14063 2773 0.83 0.856666667 0.045622617 Up 0.09909173 F2rl1 coagulation factor II (thrombin) receptor-like 1 K04234|1|0.0|748|mmu:14063|coagulation factor II (thrombin) receptor-like 1 GO:0042995//cell projection;GO:0016021//integral component of membrane GO:0008528//G-protein coupled peptide receptor activity;GO:0032403//protein complex binding "GO:0002687//positive regulation of leukocyte migration;GO:0050918//positive chemotaxis;GO:0032609//interferon-gamma production;GO:0072567;GO:0032613//interleukin-10 production;GO:0032611//interleukin-1 beta production;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0001885//endothelial cell development;GO:0006911//phagocytosis, engulfment;GO:0042311//vasodilation;GO:0007596//blood coagulation;GO:0002374//cytokine secretion involved in immune response;GO:0003093//regulation of glomerular filtration;GO:0043410//positive regulation of MAPK cascade;GO:0070945//neutrophil mediated killing of gram-negative bacterium;GO:0002285;GO:0032675//regulation of interleukin-6 production;GO:0002274;GO:0007254//JNK cascade;GO:0031269//pseudopodium assembly;GO:0032682//negative regulation of chemokine production;GO:0050715//positive regulation of cytokine secretion;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030042//actin filament depolymerization;GO:0097028//dendritic cell differentiation;GO:0002696//positive regulation of leukocyte activation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0051480//regulation of cytosolic calcium ion concentration" gi|171542817|ref|NP_032000.3|/0/proteinase-activated receptor 2 precursor [Mus musculus] 269397 4395 0.813333333 0.843333333 0.052256237 Up 0.09909173 Ss18l1 synovial sarcoma translocation gene on chromosome 18-like 1 K15623|1|2e-81|307|lve:103080497|protein SSXT "GO:0000794//condensed nuclear chromosome;GO:0000775//chromosome, centromeric region;GO:0044451" - "GO:0010975//regulation of neuron projection development;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" gi|50510593|dbj|BAD32282.1|/6.73617e-144/mKIAA0693 protein [Mus musculus] 67430 2618 0.746666667 0.773333333 0.050626073 Up 0.09909173 4921536K21Rik RIKEN cDNA 4921536K21 gene - - - - gi|13385654|ref|NP_080426.1|/5.32049e-90/uncharacterized protein C5orf52 homolog [Mus musculus] 626848 1866.89 3.876666667 3.82 -0.021244053 Down 0.099072925 Etohi1 zinc finger protein 971 K09228|1|3e-29|131|mmu:664987|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|755502181|ref|XP_011248138.1|/1.19137e-41/PREDICTED: zinc finger protein 431-like [Mus musculus] 53625 2699 4.953333333 4.89 -0.018565245 Down 0.099072925 B3gnt2 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2" "K00741|1|0.0|824|mmu:53625|N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.149]" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane "GO:0016758//transferase activity, transferring hexosyl groups;GO:0016758//transferase activity, transferring hexosyl groups" GO:0007606//sensory perception of chemical stimulus;GO:0006935//chemotaxis;GO:0006464//cellular protein modification process;GO:0007606//sensory perception of chemical stimulus;GO:0006935//chemotaxis;GO:0006464//cellular protein modification process "gi|31542175|ref|NP_058584.3|/0/N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 [Mus musculus]" 67292 3292.02 3.82 3.763333333 -0.021561558 Down 0.099072925 Pigc "phosphatidylinositol glycan anchor biosynthesis, class C" "K03859|1|1e-160|570|mmu:67292|phosphatidylinositol glycan, class C" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0031090//organelle membrane GO:0008375//acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity GO:0006497//protein lipidation;GO:0006497//protein lipidation "gi|148707359|gb|EDL39306.1|/1.04562e-162/phosphatidylinositol glycan anchor biosynthesis, class C, isoform CRA_a, partial [Mus musculus]" 72512 2179 4.22 4.283333333 0.021490955 Up 0.099072925 Tmem173 transmembrane protein 173 K12654|1|0.0|672|mmu:72512|transmembrane protein 173 GO:0042579//microbody;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0042579//microbody;GO:0031966//mitochondrial membrane;GO:0044425;GO:0042579//microbody;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane GO:0044389//ubiquitin-like protein ligase binding;GO:0030551//cyclic nucleotide binding;GO:0042802//identical protein binding;GO:0019900//kinase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0030551//cyclic nucleotide binding;GO:0042802//identical protein binding;GO:0019900//kinase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0030551//cyclic nucleotide binding;GO:0042802//identical protein binding;GO:0019900//kinase binding "GO:0006366//transcription from RNA polymerase II promoter;GO:0012501//programmed cell death;GO:0043393//regulation of protein binding;GO:0032606//type I interferon production;GO:0050691//regulation of defense response to virus by host;GO:0000060//protein import into nucleus, translocation;GO:0043330//response to exogenous dsRNA;GO:0042307//positive regulation of protein import into nucleus;GO:0035456//response to interferon-beta;GO:0006366//transcription from RNA polymerase II promoter;GO:0043393//regulation of protein binding;GO:0032606//type I interferon production;GO:0050691//regulation of defense response to virus by host;GO:0000060//protein import into nucleus, translocation;GO:0043330//response to exogenous dsRNA;GO:0042307//positive regulation of protein import into nucleus;GO:0035456//response to interferon-beta;GO:0006366//transcription from RNA polymerase II promoter;GO:0012501//programmed cell death;GO:0043393//regulation of protein binding;GO:0032606//type I interferon production;GO:0050691//regulation of defense response to virus by host;GO:0000060//protein import into nucleus, translocation;GO:0043330//response to exogenous dsRNA;GO:0042307//positive regulation of protein import into nucleus;GO:0035456//response to interferon-beta" "gi|148664727|gb|EDK97143.1|/0/mCG121990, isoform CRA_b, partial [Mus musculus]" 223989 7765 3.743333333 3.806666667 0.024204723 Up 0.099072925 Marf1 meiosis arrest female 1 K17573|1|0.0|3288|mmu:223989|meiosis arrest female protein 1 GO:0042579//microbody GO:0003676//nucleic acid binding;GO:0036094//small molecule binding GO:0048869//cellular developmental process;GO:0007126//meiotic nuclear division;GO:0007292//female gamete generation;GO:0010467//gene expression;GO:0010921//regulation of phosphatase activity gi|124487213|ref|NP_001074623.1|/0/meiosis arrest female protein 1 [Mus musculus] 14859 1422.33 4.75 4.813333333 0.019108823 Up 0.099072925 Gsta3 "glutathione S-transferase, alpha 3" K00799|1|2e-122|441|mmu:14859|glutathione S-transferase [EC:2.5.1.18] GO:0044424;GO:0044424 "GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups" - gi|31981724|ref|NP_034486.2|/2.15208e-121/glutathione S-transferase A3 isoform a [Mus musculus] 57316 2957 4.33 4.273333333 -0.019005169 Down 0.099072925 C1d C1D nuclear receptor co-repressor K12592|1|2e-73|280|mmu:57316|exosome complex protein LRP1 GO:0000178//exosome (RNase complex);GO:0031981//nuclear lumen GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0005102//receptor binding "GO:0012501//programmed cell death;GO:0006364//rRNA processing;GO:0006351//transcription, DNA-templated" gi|31542251|ref|NP_065583.2|/1.98115e-72/nuclear nucleic acid-binding protein C1D [Mus musculus] 100043147 1984 4.413333333 4.35 -0.020853315 Down 0.099072925 Gm4262 predicted gene 4262 "K04257|1|1e-12|77.4|mmu:259023|olfactory receptor;K06751|2|2e-12|77.0|mmu:100529082|major histocompatibility complex, class I;K10738|3|5e-12|75.5|hro:HELRODRAFT_74084|DNA helicase MCM9 [EC:3.6.4.12];K14306|4|1e-11|74.3|hro:HELRODRAFT_84833|nuclear pore complex protein Nup62" - - - "gi|148664918|gb|EDK97334.1|/2.31547e-71/mCG144827, partial [Mus musculus]" 72480 3916 5.096666667 5.153333333 0.015951913 Up 0.099072925 Tspyl4 TSPY-like 4 K11287|1|0.0|700|mmu:72480|TSPY-like 4 GO:0043231//intracellular membrane-bounded organelle - GO:0034728//nucleosome organization gi|28077077|ref|NP_084479.1|/0/testis-specific Y-encoded-like protein 4 [Mus musculus] 72400 1351 3.82 3.76 -0.022839976 Down 0.099072925 Pinx1 "PIN2/TERF1 interacting, telomerase inhibitor 1" K11135|1|6e-147|523|mmu:72400|Pin2-interacting protein X1 GO:0015630//microtubule cytoskeleton;GO:0031981//nuclear lumen;GO:0000776//kinetochore GO:0003723//RNA binding GO:0000070//mitotic sister chromatid segregation;GO:0006278//RNA-dependent DNA biosynthetic process gi|18129616|ref|NP_082504.1|/5.01459e-146/PIN2/TERF1-interacting telomerase inhibitor 1 [Mus musculus] 66213 2389.06 4.356666667 4.413333333 0.018643981 Up 0.099072925 Med7 mediator complex subunit 7 K15148|1|5e-116|421|mmu:66213|mediator of RNA polymerase II transcription subunit 7 GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen "GO:0005488//binding;GO:0003712//transcription cofactor activity;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0005488//binding;GO:0003712//transcription cofactor activity;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0005488//binding;GO:0003712//transcription cofactor activity;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0005488//binding;GO:0003712//transcription cofactor activity;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter;GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter;GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter;GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter gi|157266302|ref|NP_079702.3|/4.28172e-115/mediator of RNA polymerase II transcription subunit 7 [Mus musculus] 14104 9938 4.103333333 4.163333333 0.020942715 Up 0.099072925 Fasn fatty acid synthase "K00665|1|0.0|4764|mmu:14104|fatty acid synthase, animal type [EC:2.3.1.85]" GO:0048770;GO:0016020//membrane GO:0043168//anion binding;GO:0016297//acyl-[acyl-carrier-protein] hydrolase activity;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0019171//3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity GO:0006631//fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0070670//response to interleukin-4 "gi|148702861|gb|EDL34808.1|/0/fatty acid synthase, isoform CRA_a, partial [Mus musculus]" 23971 2663.97 5.703333333 5.763333333 0.015098109 Up 0.099072925 Papss1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 K13811|1|0.0|1255|mmu:23971|3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25] GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part GO:0032550;GO:0004779//sulfate adenylyltransferase activity;GO:0016301//kinase activity;GO:0032550;GO:0004779//sulfate adenylyltransferase activity;GO:0016301//kinase activity;GO:0032550;GO:0004779//sulfate adenylyltransferase activity;GO:0016301//kinase activity;GO:0032550;GO:0004779//sulfate adenylyltransferase activity;GO:0016301//kinase activity GO:0048731//system development;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0048731//system development;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0048731//system development;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0048731//system development;GO:0009152//purine ribonucleotide biosynthetic process;GO:0006790//sulfur compound metabolic process gi|545552192|ref|XP_851070.2|/0/PREDICTED: bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 isoform X1 [Canis lupus familiaris] 384569 8372 3.663333333 3.603333333 -0.023824863 Down 0.099072925 Nova2 neuro-oncological ventral antigen 2 K14944|1|9e-132|475|chx:102191643|RNA-binding protein Nova GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding - gi|119577801|gb|EAW57397.1|/1.33771e-135/neuro-oncological ventral antigen 2 [Homo sapiens] 19339 1487.37 42.13333333 42.30333333 0.005809289 Up 0.099007108 Rab3a "RAB3A, member RAS oncogene family" K07882|1|3e-124|447|pale:102880383|Ras-related protein Rab-3A GO:0032991//macromolecular complex;GO:0030665//clathrin-coated vesicle membrane;GO:0030658//transport vesicle membrane;GO:0030141//secretory granule;GO:0032991//macromolecular complex;GO:0030665//clathrin-coated vesicle membrane;GO:0030658//transport vesicle membrane;GO:0030141//secretory granule GO:0008047//enzyme activator activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0019899//enzyme binding;GO:0008047//enzyme activator activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0019899//enzyme binding GO:0009628//response to abiotic stimulus;GO:0050954//sensory perception of mechanical stimulus;GO:0006887//exocytosis;GO:0043954//cellular component maintenance;GO:0001505//regulation of neurotransmitter levels;GO:0043462//regulation of ATPase activity;GO:0009154//purine ribonucleotide catabolic process;GO:0007265//Ras protein signal transduction;GO:0045184//establishment of protein localization;GO:0031338//regulation of vesicle fusion;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0030323//respiratory tube development;GO:0006835//dicarboxylic acid transport;GO:0009628//response to abiotic stimulus;GO:0050954//sensory perception of mechanical stimulus;GO:0006887//exocytosis;GO:0043954//cellular component maintenance;GO:0001505//regulation of neurotransmitter levels;GO:0043462//regulation of ATPase activity;GO:0009154//purine ribonucleotide catabolic process;GO:0007265//Ras protein signal transduction;GO:0045184//establishment of protein localization;GO:0031338//regulation of vesicle fusion;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0030323//respiratory tube development;GO:0006835//dicarboxylic acid transport gi|635037060|ref|XP_007993972.1|/8.61552e-126/PREDICTED: ras-related protein Rab-3A [Chlorocebus sabaeus] 56724 1171 19.64333333 19.81333333 0.01243185 Up 0.099007108 Cript cysteine-rich PDZ-binding protein K19619|1|4e-31|137|smm:Smp_132860|tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-] GO:0044327//dendritic spine head;GO:0044297//cell body;GO:0044424 GO:0019904//protein domain specific binding GO:0008104//protein localization;GO:0000226//microtubule cytoskeleton organization gi|9845244|ref|NP_063972.1|/7.34358e-55/cysteine-rich PDZ-binding protein [Rattus norvegicus] 72170 1245 16.99666667 17.16666667 0.014358094 Up 0.099007108 Chchd4 coiled-coil-helix-coiled-coil-helix domain containing 4 K17782|1|1e-68|263|mmu:72170|mitochondrial intermembrane space import and assembly protein 40 GO:0005740//mitochondrial envelope GO:0015036//disulfide oxidoreductase activity GO:0006626//protein targeting to mitochondrion;GO:0006458//'de novo' protein folding gi|19527144|ref|NP_598689.1|/8.30222e-68/mitochondrial intermembrane space import and assembly protein 40 [Mus musculus] 70078 1811 19.83 20.00333333 0.012555752 Up 0.099007108 Nol7 nucleolar protein 7 K11415|1|3e-13|79.3|clv:102093099|NAD-dependent deacetylase sirtuin 5 [EC:3.5.1.-] GO:0005634//nucleus - - "gi|148709048|gb|EDL40994.1|/2.05854e-79/nucleolar protein 7, isoform CRA_c, partial [Mus musculus]" 68036 4485 24.95333333 25.12666667 0.009986747 Up 0.099007108 Zfp706 zinc finger protein 706 "K04257|1|2e-12|78.6|mmu:259023|olfactory receptor;K06751|2|5e-12|77.0|mmu:100529082|major histocompatibility complex, class I" GO:0044464 GO:0046914//transition metal ion binding - "gi|148664918|gb|EDK97334.1|/1.99424e-34/mCG144827, partial [Mus musculus]" 66679 1755 17.19 17.35 0.013366118 Up 0.098734439 Rae1 ribonucleic acid export 1 K14298|1|0.0|741|chx:102169026|mRNA export factor GO:0043231//intracellular membrane-bounded organelle - GO:0014070//response to organic cyclic compound gi|548490388|ref|XP_005688372.1|/0/PREDICTED: mRNA export factor isoform X1 [Capra hircus] 243078 2373 27.34666667 27.18333333 -0.008642615 Down 0.098734439 Tecrl "trans-2,3-enoyl-CoA reductase-like" K10258|1|3e-96|355|phi:106628096|very-long-chain enoyl-CoA reductase [EC:1.3.1.93] GO:0044424;GO:0031224//intrinsic component of membrane GO:0016491//oxidoreductase activity GO:0044710;GO:0044238//primary metabolic process "gi|254540076|ref|NP_722496.2|/0/trans-2,3-enoyl-CoA reductase-like [Mus musculus]" 14360 3540.79 18.81 18.65 -0.012324218 Down 0.098734439 Fyn Fyn proto-oncogene K05703|1|0.0|1064|cfr:102506492|tyrosine-protein kinase Fyn [EC:2.7.10.2] GO:0016020//membrane;GO:0044327//dendritic spine head;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0044327//dendritic spine head;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0044327//dendritic spine head;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0032550;GO:0051427//hormone receptor binding;GO:0004713//protein tyrosine kinase activity;GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding;GO:0032550;GO:0051427//hormone receptor binding;GO:0004713//protein tyrosine kinase activity;GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding;GO:0004713//protein tyrosine kinase activity;GO:0051427//hormone receptor binding;GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding GO:0016358//dendrite development;GO:0022604//regulation of cell morphogenesis;GO:0010467//gene expression;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0050851//antigen receptor-mediated signaling pathway;GO:0010975//regulation of neuron projection development;GO:0009895;GO:0007420//brain development;GO:0006468//protein phosphorylation;GO:0097305//response to alcohol;GO:0019233//sensory perception of pain;GO:0008366//axon ensheathment;GO:0016477//cell migration;GO:0042098//T cell proliferation;GO:0016358//dendrite development;GO:0022604//regulation of cell morphogenesis;GO:0010467//gene expression;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0050851//antigen receptor-mediated signaling pathway;GO:0010975//regulation of neuron projection development;GO:0009895;GO:0007420//brain development;GO:0006468//protein phosphorylation;GO:0097305//response to alcohol;GO:0019233//sensory perception of pain;GO:0008366//axon ensheathment;GO:0016477//cell migration;GO:0042098//T cell proliferation;GO:0010467//gene expression;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0050688//regulation of defense response to virus;GO:0007215//glutamate receptor signaling pathway;GO:0007420//brain development;GO:0050851//antigen receptor-mediated signaling pathway;GO:0016358//dendrite development;GO:0070838//divalent metal ion transport;GO:0019233//sensory perception of pain;GO:0032870//cellular response to hormone stimulus;GO:0007611//learning or memory;GO:0009895;GO:0016477//cell migration;GO:0006935//chemotaxis;GO:0010975//regulation of neuron projection development;GO:0070848//response to growth factor;GO:0007599//hemostasis;GO:0035556//intracellular signal transduction;GO:0022604//regulation of cell morphogenesis;GO:0042098//T cell proliferation;GO:0097305//response to alcohol;GO:0006468//protein phosphorylation;GO:0031294//lymphocyte costimulation gi|880897894|ref|XP_012971238.1|/0/PREDICTED: tyrosine-protein kinase Fyn isoform X1 [Mesocricetus auratus] 627828 1604 23.74 23.89666667 0.009489456 Up 0.098734439 Gm6793 heterogeneous nuclear ribonucleoprotein A3 pseudogene K12741|1|6e-107|390|chx:102172646|heterogeneous nuclear ribonucleoprotein A1/A3 GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen;GO:0042995//cell projection GO:0003723//RNA binding;GO:0051032;GO:0036094//small molecule binding GO:0006396//RNA processing;GO:0050658//RNA transport gi|585645604|ref|XP_006882199.1|/5.59561e-110/PREDICTED: heterogeneous nuclear ribonucleoprotein A3-like [Elephantulus edwardii] 20226 3649.08 30.26333333 30.10333333 -0.007647656 Down 0.098734439 Sars seryl-aminoacyl-tRNA synthetase K01875|1|0.0|964|ocu:100339002|seryl-tRNA synthetase [EC:6.1.1.11] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity;GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation;GO:0006418//tRNA aminoacylation for protein translation "gi|33468931|ref|NP_035449.1|/0/serine--tRNA ligase, cytoplasmic isoform 1 [Mus musculus]" 108958 3409.93 31.65 31.49 -0.007311742 Down 0.098734439 Fam73b "family with sequence similarity 73, member B" - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0001501//skeletal system development;GO:0001501//skeletal system development gi|74178322|dbj|BAE32434.1|/0/unnamed protein product [Mus musculus] 19732 2967 17.06 16.9 -0.0135944 Down 0.098734439 Rgl2 ral guanine nucleotide dissociation stimulator-like 2 K17636|1|0.0|1181|mmu:19732|ral guanine nucleotide dissociation stimulator-like 2 GO:0044464 - GO:0007264//small GTPase mediated signal transduction gi|46195800|ref|NP_033085.2|/0/ral guanine nucleotide dissociation stimulator-like 2 [Mus musculus] 13653 3072 20.95333333 21.11666667 0.011202347 Up 0.098734439 Egr1 early growth response 1 K09203|1|0.0|810|mmu:13653|early growth response protein 1 GO:0043231//intracellular membrane-bounded organelle "GO:0046872//metal ion binding;GO:0043566//structure-specific DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0019899//enzyme binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding" GO:0043065//positive regulation of apoptotic process;GO:0016925//protein sumoylation;GO:0071407//cellular response to organic cyclic compound;GO:0030098//lymphocyte differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0043434//response to peptide hormone;GO:0010332//response to gamma radiation;GO:0019221//cytokine-mediated signaling pathway;GO:0044708//single-organism behavior;GO:0030178//negative regulation of Wnt signaling pathway;GO:0072126//positive regulation of glomerular mesangial cell proliferation;GO:0071417//cellular response to organonitrogen compound;GO:0006366//transcription from RNA polymerase II promoter;GO:0009746;GO:0007519//skeletal muscle tissue development;GO:0048168//regulation of neuronal synaptic plasticity gi|1325982|gb|AAB00468.1|/0/zinc finger protein [Mus musculus] 270166 2869.17 25.98666667 26.15 0.009039357 Up 0.098734439 Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit K03544|1|0.0|1068|mmu:270166|ATP-dependent Clp protease ATP-binding subunit ClpX GO:0031981//nuclear lumen;GO:0005759//mitochondrial matrix;GO:0019866//organelle inner membrane;GO:0031981//nuclear lumen;GO:0005759//mitochondrial matrix;GO:0019866//organelle inner membrane "GO:0032550;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0043169//cation binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0043169//cation binding;GO:0042623//ATPase activity, coupled" GO:0044267//cellular protein metabolic process;GO:0051345//positive regulation of hydrolase activity;GO:0009154//purine ribonucleotide catabolic process;GO:0006508//proteolysis;GO:0044267//cellular protein metabolic process;GO:0051345//positive regulation of hydrolase activity;GO:0009154//purine ribonucleotide catabolic process;GO:0006508//proteolysis "gi|113205069|ref|NP_001037854.1|/0/ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial isoform 2 [Mus musculus]" 105242579 1667 0.343333333 0.32 -0.101538026 Down 0.098640415 LOC105242579 uncharacterized LOC105242579 - - - - - 13380 2245 0.24 0.256666667 0.096861539 Up 0.098640415 Dkk1 dickkopf WNT signaling pathway inhibitor 1 K02165|1|3e-151|538|mmu:13380|dickkopf - - - - 245527 4753 0.283333333 0.303333333 0.098403704 Up 0.098640415 Eda2r ectodysplasin A2 receptor K05163|1|5e-164|582|mmu:245527|tumor necrosis factor receptor superfamily member 27 - - - - 319765 3902 2.426666667 2.47 0.025535092 Up 0.098593403 Igf2bp2 insulin-like growth factor 2 mRNA binding protein 2 K17392|1|0.0|1090|mmu:319765|insulin-like growth factor 2 mRNA-binding protein 2 GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle GO:0003729//mRNA binding;GO:0036094//small molecule binding GO:0006412//translation "gi|148665207|gb|EDK97623.1|/0/insulin-like growth factor 2 mRNA binding protein 2, isoform CRA_d, partial [Mus musculus]" 243906 3491 1.64 1.68 0.034765418 Up 0.098593403 Zfp14 zinc finger protein 14 K09228|1|0.0|1078|mmu:243906|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|60360420|dbj|BAD90454.1|/0/mKIAA1559 protein [Mus musculus] 26399 2064 2.096666667 2.14 0.02951328 Up 0.098593403 Map2k6 mitogen-activated protein kinase kinase 6 K04433|1|0.0|657|mmu:26399|mitogen-activated protein kinase kinase 6 [EC:2.7.12.2] GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0032550;GO:0004672//protein kinase activity;GO:0019900//kinase binding "GO:0006351//transcription, DNA-templated;GO:0006941//striated muscle contraction;GO:0042221//response to chemical;GO:0006915//apoptotic process;GO:0006468//protein phosphorylation" gi|507673141|ref|XP_004709231.1|/0/PREDICTED: dual specificity mitogen-activated protein kinase kinase 6 [Echinops telfairi] 12818 6465 1.886666667 1.843333333 -0.033522573 Down 0.098593403 Col14a1 "collagen, type XIV, alpha 1" "K08133|1|0.0|2774|mmu:12818|collagen, type XIV, alpha" GO:0005578//proteinaceous extracellular matrix - GO:0022610;GO:0001894//tissue homeostasis;GO:0001558//regulation of cell growth;GO:0030198//extracellular matrix organization "gi|148697327|gb|EDL29274.1|/0/procollagen, type XIV, alpha 1, isoform CRA_c, partial [Mus musculus]" 70673 8433.6 1.836666667 1.796666667 -0.031767046 Down 0.098593403 Prdm16 PR domain containing 16 K04462|1|0.0|1025|oas:101121055|ecotropic virus integration site 1 protein GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0007423//sensory organ development;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0043467//regulation of generation of precursor metabolites and energy;GO:0045444//fat cell differentiation;GO:0019827//stem cell population maintenance;GO:0007399//nervous system development;GO:0006351//transcription, DNA-templated;GO:0007423//sensory organ development;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0043467//regulation of generation of precursor metabolites and energy;GO:0045444//fat cell differentiation;GO:0019827//stem cell population maintenance;GO:0007399//nervous system development;GO:0006351//transcription, DNA-templated;GO:0007423//sensory organ development;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0043467//regulation of generation of precursor metabolites and energy;GO:0045444//fat cell differentiation;GO:0019827//stem cell population maintenance;GO:0007399//nervous system development;GO:0006351//transcription, DNA-templated;GO:0007423//sensory organ development;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0043467//regulation of generation of precursor metabolites and energy;GO:0045444//fat cell differentiation;GO:0019827//stem cell population maintenance;GO:0007399//nervous system development" gi|295789156|ref|NP_001171466.1|/0/PR domain zinc finger protein 16 isoform 2 [Mus musculus] 70297 6528 2.01 2.053333333 0.030772349 Up 0.098593403 Gcc2 GRIP and coiled-coil domain containing 2 K20282|1|0.0|3052|mmu:70297|GRIP and coiled-coil domain-containing protein 2 - - - - 320615 9124 1.956666667 1.996666667 0.0291955 Up 0.098593403 Dopey1 dopey family member 1 K19476|1|3e-55|221|tsp:Tsp_05230|vacuolar protein sorting-associated protein IST1;K01836|4|3e-07|62.4|mmu:109785|phosphoacetylglucosamine mutase [EC:5.4.2.3] - - - gi|190194414|ref|NP_796182.2|/0/protein dopey-1 [Mus musculus] 14745 3451 2.323333333 2.366666667 0.026660369 Up 0.098593403 Lpar1 lysophosphatidic acid receptor 1 K04289|1|0.0|719|rno:116744|lysophosphatidic acid receptor 1 "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0030425//dendrite;GO:0031224//intrinsic component of membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0030425//dendrite;GO:0031224//intrinsic component of membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0030425//dendrite;GO:0031224//intrinsic component of membrane" GO:0019904//protein domain specific binding;GO:0008289//lipid binding;GO:0045125//bioactive lipid receptor activity;GO:0019904//protein domain specific binding;GO:0008289//lipid binding;GO:0045125//bioactive lipid receptor activity;GO:0019904//protein domain specific binding;GO:0008289//lipid binding;GO:0045125//bioactive lipid receptor activity GO:0051094//positive regulation of developmental process;GO:0007266//Rho protein signal transduction;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0070887//cellular response to chemical stimulus;GO:0010975//regulation of neuron projection development;GO:0006915//apoptotic process;GO:0006468//protein phosphorylation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0000165//MAPK cascade;GO:0030031//cell projection assembly;GO:0008366//axon ensheathment;GO:0014911//positive regulation of smooth muscle cell migration;GO:0051094//positive regulation of developmental process;GO:0007266//Rho protein signal transduction;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0070887//cellular response to chemical stimulus;GO:0010975//regulation of neuron projection development;GO:0006915//apoptotic process;GO:0006468//protein phosphorylation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0000165//MAPK cascade;GO:0030031//cell projection assembly;GO:0008366//axon ensheathment;GO:0014911//positive regulation of smooth muscle cell migration;GO:0051094//positive regulation of developmental process;GO:0007266//Rho protein signal transduction;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0070887//cellular response to chemical stimulus;GO:0010975//regulation of neuron projection development;GO:0006915//apoptotic process;GO:0006468//protein phosphorylation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0000165//MAPK cascade;GO:0030031//cell projection assembly;GO:0008366//axon ensheathment;GO:0014911//positive regulation of smooth muscle cell migration "gi|148670279|gb|EDL02226.1|/0/endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2, isoform CRA_a, partial [Mus musculus]" 213054 8606 2.123333333 2.166666667 0.029146346 Up 0.098593403 Gabpb2 "GA repeat binding protein, beta 2" "K09454|1|0.0|674|mmu:213054|GA-binding protein transcription factor, beta" - GO:0000975//regulatory region DNA binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter "gi|148706839|gb|EDL38786.1|/0/GA repeat binding protein, beta 2, isoform CRA_b, partial [Mus musculus]" 270669 4799 2.21 2.25 0.025878632 Up 0.098593403 Mbtps2 "membrane-bound transcription factor peptidase, site 2" K07765|1|0.0|947|mmu:270669|S2P endopeptidase [EC:3.4.24.85] GO:0031224//intrinsic component of membrane;GO:0044424 GO:0004175//endopeptidase activity;GO:0043169//cation binding GO:0019538//protein metabolic process;GO:0016125//sterol metabolic process gi|26986629|ref|NP_758511.1|/0/membrane-bound transcription factor site-2 protease [Mus musculus] 13446 2557 1.993333333 2.03 0.026296744 Up 0.098593403 Doc2a "double C2, alpha" K19916|1|1e-170|602|mmu:13446|double C2-like domain-containing protein alpha GO:0000323//lytic vacuole;GO:0008021//synaptic vesicle - GO:0017156//calcium ion regulated exocytosis gi|33859540|ref|NP_034199.1|/1.12598e-169/double C2-like domain-containing protein alpha [Mus musculus] 16439 11800.64 2.2 2.24 0.025995209 Up 0.098593403 Itpr2 "inositol 1,4,5-triphosphate receptor 2" "K04959|1|0.0|5093|mmu:16439|inositol 1,4,5-triphosphate receptor type 2" GO:0043005//neuron projection;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane GO:0005262//calcium channel activity;GO:0005217//intracellular ligand-gated ion channel activity;GO:0005543//phospholipid binding;GO:0046872//metal ion binding;GO:0043168//anion binding;GO:0005262//calcium channel activity;GO:0005217//intracellular ligand-gated ion channel activity;GO:0005543//phospholipid binding;GO:0046872//metal ion binding;GO:0043168//anion binding GO:0015980//energy derivation by oxidation of organic compounds;GO:0007599//hemostasis;GO:0038127//ERBB signaling pathway;GO:0045471//response to ethanol;GO:0006816//calcium ion transport;GO:0010863//positive regulation of phospholipase C activity;GO:0001666//response to hypoxia;GO:0030073//insulin secretion;GO:0051591//response to cAMP;GO:0001775//cell activation;GO:0019932//second-messenger-mediated signaling;GO:0015980//energy derivation by oxidation of organic compounds;GO:0007599//hemostasis;GO:0038127//ERBB signaling pathway;GO:0045471//response to ethanol;GO:0006816//calcium ion transport;GO:0010863//positive regulation of phospholipase C activity;GO:0001666//response to hypoxia;GO:0030073//insulin secretion;GO:0051591//response to cAMP;GO:0001775//cell activation;GO:0019932//second-messenger-mediated signaling "gi|60593032|ref|NP_064307.2|/0/inositol 1,4,5-trisphosphate receptor type 2 isoform 1 [Mus musculus]" 20592 5471 1.72 1.76 0.033166864 Up 0.098593403 Kdm5d lysine (K)-specific demethylase 5D K11446|1|0.0|2942|mmu:20592|histone demethylase JARID1 [EC:1.14.11.-] GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0032452//histone demethylase activity;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0070076//histone lysine demethylation gi|33859626|ref|NP_035549.1|/0/lysine-specific demethylase 5D [Mus musculus] 67897 5018 1.91 1.87 -0.030534368 Down 0.098593403 Rnmt RNA (guanine-7-) methyltransferase K00565|1|0.0|753|mmu:67897|mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56] GO:0034518//RNA cap binding complex;GO:0031981//nuclear lumen;GO:0034518//RNA cap binding complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0008170//N-methyltransferase activity;GO:0003676//nucleic acid binding;GO:0008170//N-methyltransferase activity GO:0001510//RNA methylation;GO:0006397//mRNA processing;GO:0001510//RNA methylation;GO:0006397//mRNA processing gi|283945577|ref|NP_001164424.1|/0/mRNA cap guanine-N7 methyltransferase isoform 2 [Mus musculus] 240614 4867 1.93 1.973333333 0.032033828 Up 0.098593403 Ranbp6 RAN binding protein 6 K20222|1|0.0|1748|cjc:100404460|importin-5 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0045184//establishment of protein localization gi|53850664|ref|NP_808389.2|/0/ran-binding protein 6 [Mus musculus] 209645 3837 1.903333333 1.943333333 0.030005138 Up 0.098593403 Bend7 BEN domain containing 7 - - - - gi|298676447|ref|NP_001177329.1|/0/BEN domain-containing protein 7 isoform 2 [Mus musculus] 217995 6776 1.936666667 1.896666667 -0.030109511 Down 0.098593403 Heatr1 HEAT repeat containing 1 K14550|1|0.0|4111|mmu:217995|U3 small nucleolar RNA-associated protein 10 GO:0032991//macromolecular complex;GO:0031981//nuclear lumen GO:0005488//binding GO:0042254//ribosome biogenesis gi|46519149|ref|NP_659084.3|/0/HEAT repeat-containing protein 1 [Mus musculus] 240595 5092 1.746666667 1.71 -0.030607986 Down 0.098593403 Kcnv2 "potassium channel, subfamily V, member 2" K04935|1|0.0|1036|mmu:240595|potassium channel subfamily V member 2 GO:0005887//integral component of plasma membrane GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity GO:0051259//protein oligomerization;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|34147232|ref|NP_899002.1|/0/potassium voltage-gated channel subfamily V member 2 [Mus musculus] 74239 4359 1.84 1.88 0.031026896 Up 0.098593403 Iqce IQ motif containing E - GO:0043231//intracellular membrane-bounded organelle - - "gi|148687166|gb|EDL19113.1|/0/IQ motif containing E, isoform CRA_c, partial [Mus musculus]" 18129 10506 2.086666667 2.043333333 -0.030275583 Down 0.098593403 Notch2 notch 2 K02599|1|0.0|5101|mmu:18129|Notch GO:0031981//nuclear lumen;GO:0016021//integral component of membrane;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0046872//metal ion binding;GO:0008134//transcription factor binding GO:0007265//Ras protein signal transduction;GO:0007219//Notch signaling pathway;GO:0048771//tissue remodeling;GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0001568//blood vessel development;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0006955//immune response;GO:0045165//cell fate commitment;GO:0008283//cell proliferation;GO:0035108//limb morphogenesis;GO:0044267//cellular protein metabolic process;GO:0003177;GO:0006915//apoptotic process;GO:0009855//determination of bilateral symmetry;GO:0003209//cardiac atrium morphogenesis;GO:0043009//chordate embryonic development;GO:0003143//embryonic heart tube morphogenesis;GO:0009798//axis specification;GO:0022402//cell cycle process;GO:0012502//induction of programmed cell death;GO:0006954//inflammatory response;GO:0032633//interleukin-4 production gi|134288853|ref|NP_035058.2|/0/neurogenic locus notch homolog protein 2 precursor [Mus musculus] 269870 4856.85 1.586666667 1.623333333 0.032960199 Up 0.098593403 Zfp446 zinc finger protein 446 K09229|1|2e-124|450|rno:102552463|KRAB and SCAN domains-containing zinc finger protein - GO:0043169//cation binding;GO:0043169//cation binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|270483736|ref|NP_001162034.1|/5.26326e-145/zinc finger protein 446 isoform 3 [Mus musculus] 105246278 4107.49 1.793333333 1.753333333 -0.032543373 Down 0.098593403 B230354K17Rik RIKEN cDNA B230354K17 gene - - - - - 16798 7222 1.893333333 1.933333333 0.030161971 Up 0.098593403 Lats1 large tumor suppressor K08791|1|0.0|2012|mmu:16798|serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1] GO:0005819//spindle GO:0032550;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0019900//kinase binding GO:0001934//positive regulation of protein phosphorylation;GO:0006461//protein complex assembly;GO:0009913//epidermal cell differentiation;GO:0032507//maintenance of protein location in cell;GO:0008064//regulation of actin polymerization or depolymerization;GO:0030178//negative regulation of Wnt signaling pathway;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007059//chromosome segregation;GO:0000087//mitotic M phase;GO:0035556//intracellular signal transduction gi|161484646|ref|NP_034820.1|/0/serine/threonine-protein kinase LATS1 [Mus musculus] 108657 3056 39.13666667 39.28333333 0.005396468 Up 0.098433563 Rnpepl1 arginyl aminopeptidase (aminopeptidase B)-like 1 K09605|1|0.0|1403|mmu:108657|arginyl aminopeptidase-like 1 [EC:3.4.11.-] - - - gi|318065085|ref|NP_852070.3|/0/arginyl aminopeptidase-like 1 [Mus musculus] 20442 5784 15.45 15.3 -0.014075185 Down 0.098433563 St3gal1 "ST3 beta-galactoside alpha-2,3-sialyltransferase 1" "K00780|1|0.0|642|mmu:20442|beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A) [EC:2.4.99.4]" GO:0031228//intrinsic component of Golgi membrane GO:0008373//sialyltransferase activity GO:0006024//glycosaminoglycan biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0006493//protein O-linked glycosylation "gi|6677957|ref|NP_033203.1|/0/CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 [Mus musculus]" 101437 2962 17.23 17.38333333 0.01278205 Up 0.098433563 Dhx32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 K18994|1|0.0|1261|mmu:101437|pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 - gi|17978827|gb|AAL47579.1|/0/helicase DDX32 [Mus musculus] 16011 5854 24.16333333 24.31 0.008730405 Up 0.098433563 Igfbp5 insulin-like growth factor binding protein 5 K10138|1|2e-60|238|cjc:100393906|insulin-like growth factor-binding protein 3 GO:0005615//extracellular space GO:0005520//insulin-like growth factor binding GO:0014909//smooth muscle cell migration;GO:0001649//osteoblast differentiation;GO:0048771//tissue remodeling;GO:0033500//carbohydrate homeostasis;GO:0006412//translation;GO:0009968//negative regulation of signal transduction;GO:0001942//hair follicle development;GO:0008285//negative regulation of cell proliferation;GO:0007519//skeletal muscle tissue development;GO:0006006//glucose metabolic process;GO:0051591//response to cAMP;GO:0042692//muscle cell differentiation;GO:0016049//cell growth "gi|148667878|gb|EDL00295.1|/0/insulin-like growth factor binding protein 5, isoform CRA_b, partial [Mus musculus]" 117150 3374 17.34666667 17.49333333 0.012146758 Up 0.098433563 Pip4k2c "phosphatidylinositol-5-phosphate 4-kinase, type II, gamma" K00920|1|0.0|655|ngi:103742907|1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149] GO:0031981//nuclear lumen GO:0032550;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0005515//protein binding GO:0046474//glycerophospholipid biosynthetic process gi|674070361|ref|XP_008842284.1|/0/PREDICTED: phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X1 [Nannospalax galili] 14465 3194 21.67666667 21.82666667 0.009948898 Up 0.098433563 Gata6 GATA binding protein 6 K17897|1|0.0|893|mmu:14465|GATA-binding protein 6 GO:0031981//nuclear lumen;GO:0043234//protein complex "GO:0046872//metal ion binding;GO:0019900//kinase binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0043566//structure-specific DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding" GO:0002065;GO:0032905;GO:0006915//apoptotic process;GO:0060487//lung epithelial cell differentiation;GO:0008284//positive regulation of cell proliferation;GO:0042692//muscle cell differentiation;GO:0001709//cell fate determination;GO:0008406//gonad development;GO:0043009//chordate embryonic development;GO:0003299;GO:0006796//phosphate-containing compound metabolic process;GO:0035051//cardiocyte differentiation;GO:0032870//cellular response to hormone stimulus;GO:0001666//response to hypoxia;GO:0032906;GO:0030509//BMP signaling pathway;GO:0003151//outflow tract morphogenesis;GO:0007599//hemostasis;GO:0007050//cell cycle arrest;GO:0048545//response to steroid hormone;GO:0001525//angiogenesis;GO:0071363//cellular response to growth factor stimulus gi|46909571|ref|NP_034388.2|/0/transcription factor GATA-6 [Mus musculus] 17160 3434 17.24333333 17.09666667 -0.01232362 Down 0.098433563 Man2b2 "mannosidase 2, alpha B2" K12312|1|0.0|2020|mmu:17160|epididymis-specific alpha-mannosidase [EC:3.2.1.24] GO:0000323//lytic vacuole GO:0046914//transition metal ion binding;GO:0015923//mannosidase activity GO:0019318//hexose metabolic process gi|227330625|ref|NP_032576.2|/0/epididymis-specific alpha-mannosidase precursor [Mus musculus] 233871 3764 32.05333333 31.90333333 -0.006767227 Down 0.098433563 Atxn2l ataxin 2-like K05628|1|4e-07|40.4|lcm:102351359|arginine-glutamic acid dipeptide repeats protein;K19878|4|7e-06|47.8|dre:572002|ELKS/RAB6-interacting/CAST family member 2 GO:0016604//nuclear body;GO:0035770//ribonucleoprotein granule - GO:0033962//cytoplasmic mRNA processing body assembly "gi|148685437|gb|EDL17384.1|/0/ataxin 2-like, isoform CRA_f, partial [Mus musculus]" 66588 1880 14.92 15.07333333 0.014750956 Up 0.098433563 Cmpk1 cytidine monophosphate (UMP-CMP) kinase 1 K13800|1|2e-117|425|mmu:66588|UMP-CMP kinase [EC:2.7.4.- 2.7.4.14] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0032550;GO:0009041//uridylate kinase activity;GO:0019206//nucleoside kinase activity GO:0009197;GO:0042537//benzene-containing compound metabolic process;GO:0042698//ovulation cycle;GO:0006221//pyrimidine nucleotide biosynthetic process;GO:0009174;GO:0009194 gi|165377065|ref|NP_079923.3|/1.69377e-116/UMP-CMP kinase [Mus musculus] 77975 2237 26.38333333 26.53 0.007997826 Up 0.098433563 Tmem50b transmembrane protein 50B - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - "gi|148671875|gb|EDL03822.1|/2.33454e-91/transmembrane protein 50B, isoform CRA_a, partial [Mus musculus]" 12576 2405 17.38 17.23333333 -0.012226302 Down 0.098433563 Cdkn1b cyclin-dependent kinase inhibitor 1B K06624|1|2e-112|409|mmu:12576|cyclin-dependent kinase inhibitor 1B - - - - 26949 2732 19.53666667 19.67666667 0.010301504 Up 0.098057467 Vat1 vesicle amine transport 1 K00344|1|1e-25|121|cge:100768247|NADPH2:quinone reductase [EC:1.6.5.5] GO:0031224//intrinsic component of membrane;GO:0031966//mitochondrial membrane GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0003824//catalytic activity GO:0044710;GO:0008053//mitochondrial fusion gi|74193292|dbj|BAE32958.1|/0/unnamed protein product [Mus musculus] 67070 2724 19.17 19.03 -0.010574775 Down 0.098057467 Lsm14a LSM14A mRNA processing body assembly factor K18749|1|0.0|650|mmu:67070|protein LSM14 - - - - 105513 2706 19.48 19.34333333 -0.010157249 Down 0.098057467 Chmp7 charged multivesicular body protein 7 K15053|1|0.0|737|tup:102497867|charged multivesicular body protein 7 GO:0010008//endosome membrane GO:0022892//substrate-specific transporter activity GO:0045184//establishment of protein localization;GO:0007034//vacuolar transport gi|562821651|ref|XP_006140727.1|/0/PREDICTED: charged multivesicular body protein 7 [Tupaia chinensis] 76936 2474.29 25 25.14333333 0.00824783 Up 0.098057467 Hnrnpm heterogeneous nuclear ribonucleoprotein M K12887|1|0.0|1170|mmu:76936|heterogeneous nuclear ribonucleoprotein M GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0034399//nuclear periphery;GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0034399//nuclear periphery GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding "GO:0000398//mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome" gi|60360010|dbj|BAD90224.1|/0/mKIAA4193 protein [Mus musculus] 20187 3265.29 15.37 15.22666667 -0.013517015 Down 0.098057467 Ryk receptor-like tyrosine kinase K05128|1|0.0|931|mmu:20187|RYK receptor-like tyrosine kinase [EC:2.7.10.1] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0001664//G-protein coupled receptor binding;GO:0004888//transmembrane signaling receptor activity;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0001664//G-protein coupled receptor binding;GO:0004888//transmembrane signaling receptor activity;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0001664//G-protein coupled receptor binding;GO:0004888//transmembrane signaling receptor activity GO:0001501//skeletal system development;GO:0007411//axon guidance;GO:0007166//cell surface receptor signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0000165//MAPK cascade;GO:0006464//cellular protein modification process;GO:0030517//negative regulation of axon extension;GO:0021537//telencephalon development;GO:0001501//skeletal system development;GO:0007411//axon guidance;GO:0007166//cell surface receptor signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0000165//MAPK cascade;GO:0006464//cellular protein modification process;GO:0030517//negative regulation of axon extension;GO:0021537//telencephalon development;GO:0001501//skeletal system development;GO:0007411//axon guidance;GO:0007166//cell surface receptor signaling pathway;GO:0006796//phosphate-containing compound metabolic process;GO:0000165//MAPK cascade;GO:0006464//cellular protein modification process;GO:0030517//negative regulation of axon extension;GO:0021537//telencephalon development gi|110681700|ref|NP_038677.3|/0/tyrosine-protein kinase RYK isoform 1 precursor [Mus musculus] 381269 2493 14.11333333 14.25 0.013903151 Up 0.098057467 Mreg melanoregulin - GO:0044459 - GO:0050931//pigment cell differentiation;GO:0022405//hair cycle process gi|53749212|ref|NP_001005423.1|/1.77797e-95/melanoregulin [Mus musculus] 22134 5025 18.29 18.43333333 0.011261905 Up 0.098057467 Tgoln1 trans-golgi network protein K04490|1|2e-10|71.6|aam:106497459|transcription factor 7-like 1 GO:0005798//Golgi-associated vesicle;GO:0016020//membrane GO:0005488//binding - gi|6678459|ref|NP_033469.1|/3.48474e-144/trans-Golgi network integral membrane protein 1 precursor [Mus musculus] 71767 1920.1 17.71333333 17.57 -0.011721536 Down 0.098057467 Tysnd1 trypsin domain containing 1 K13908|1|9e-06|55.1|mcc:720912|mucin-5B GO:0042579//microbody;GO:0042579//microbody;GO:0042579//microbody;GO:0042579//microbody GO:0004175//endopeptidase activity;GO:0019899//enzyme binding;GO:0004175//endopeptidase activity;GO:0019899//enzyme binding;GO:0004175//endopeptidase activity;GO:0019899//enzyme binding;GO:0004175//endopeptidase activity;GO:0019899//enzyme binding GO:0051259//protein oligomerization;GO:0051604//protein maturation;GO:0006635//fatty acid beta-oxidation;GO:0051259//protein oligomerization;GO:0051604//protein maturation;GO:0006635//fatty acid beta-oxidation;GO:0051259//protein oligomerization;GO:0051604//protein maturation;GO:0006635//fatty acid beta-oxidation;GO:0051259//protein oligomerization;GO:0051604//protein maturation;GO:0006635//fatty acid beta-oxidation gi|254675122|ref|NP_082188.1|/0/peroxisomal leader peptide-processing protease isoform a [Mus musculus] 17939 1913 15.84 15.98 0.012695073 Up 0.098057467 Naga "N-acetyl galactosaminidase, alpha" K01204|1|0.0|834|mmu:17939|alpha-N-acetylgalactosaminidase [EC:3.2.1.49] - - - gi|19547877|gb|AAL87527.1|/0/alpha-N-acetyl-galactosaminidase [Mus musculus] 212085 588 0.263333333 0.246666667 -0.094327383 Down 0.097991651 Trim52 tripartite motif-containing 52 K12025|1|8e-122|441|mmu:212085|tripartite motif-containing protein 52 - - - gi|148668196|gb|EDL00526.1|/4.11911e-121/mCG1042451 [Mus musculus] 16565 9119 0.26 0.276666667 0.089637212 Up 0.097991651 Kif21b kinesin family member 21B K10395|1|0.0|2754|mmu:16565|kinesin family member 4/21/27 - - - - 474332 7928 0.32 0.34 0.087462841 Up 0.097991651 Dnm3os "dynamin 3, opposite strand" - - - - gi|51890509|dbj|BAD42838.1|/1.0143e-84/hypothetical protein [Mus musculus] 100151693 1338 0.256666667 0.273333333 0.090765464 Up 0.097991651 Gm10364 glyceraldehyde-3-phosphate dehydrogenase pseudogene K00134|1|1e-133|293|mmu:14433|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] - - - - 545192 4645 0.273333333 0.29 0.085391491 Up 0.097991651 Baiap3 BAI1-associated protein 3 K15621|1|0.0|2072|mmu:545192|BAI1-associated protein 3 - - - gi|253795532|ref|NP_001156742.1|/0/BAI1-associated protein 3 [Mus musculus] 434197 2831 0.363333333 0.386666667 0.08979667 Up 0.097991651 Fam169b "family with sequence similarity 169, member B" K12869|1|4e-75|285|gfr:102042741|crooked neck - - - gi|62000668|ref|NP_001013833.1|/0/protein FAM169B [Mus musculus] 195733 3487 0.343333333 0.323333333 -0.086587685 Down 0.097991651 Grhl1 grainyhead-like 1 (Drosophila) K09275|1|0.0|993|mmu:195733|transcription factor CP2 and related proteins GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0006629//lipid metabolic process;GO:0006351//transcription, DNA-templated;GO:0032502//developmental process;GO:0032502//developmental process;GO:0010467//gene expression" gi|20502767|gb|AAM22617.1|AF411211_1/0/p61 MGR [Mus musculus] 70891 1891 0.29 0.273333333 -0.085391491 Down 0.097991651 Spdya "speedy/RINGO cell cycle regulator family, member A" K08694|1|8e-162|572|mmu:70891|speedy - - - - 20714 1652 0.35 0.373333333 0.093109404 Up 0.097991651 Serpina3k "serine (or cysteine) peptidase inhibitor, clade A, member 3K" "K04525|1|0.0|745|mmu:20714|serpin peptidase inhibitor, clade A" - - - gi|148747546|ref|NP_035588.2|/0/serine protease inhibitor A3K precursor [Mus musculus] 93716 4730 0.383333333 0.36 -0.090602549 Down 0.097991651 Pcdhga8 "protocadherin gamma subfamily A, 8" K16495|1|0.0|1711|mmu:93716|protocadherin gamma subfamily A GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|60360120|dbj|BAD90279.1|/0/mKIAA0327 protein [Mus musculus] 100503085 2142 0.323333333 0.343333333 0.086587685 Up 0.097991651 Klhl3 kelch-like 3 K10443|1|0.0|1267|mmu:100503085|kelch-like protein 2/3 - - - gi|303519514|ref|NP_001182004.1|/0/kelch-like protein 3 [Mus musculus] 319998 2199 0.266666667 0.283333333 0.087462841 Up 0.097991651 Tmem198 transmembrane protein 198 - - - - gi|28892951|ref|NP_796030.1|/5.60814e-106/transmembrane protein 198 [Mus musculus] 56216 1574 0.25 0.266666667 0.093109404 Up 0.097991651 Stx1b syntaxin 1B K08486|1|4e-134|480|shr:100929548|syntaxin 1B/2/3 GO:0016021//integral component of membrane GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0005515//protein binding GO:0007267//cell-cell signaling;GO:0006887//exocytosis;GO:0015031//protein transport gi|6981600|ref|NP_036832.1|/3.50875e-133/syntaxin-1B [Rattus norvegicus] 18616 6624 0.263333333 0.28 0.088536675 Up 0.097991651 Peg3 paternally expressed 3 K09230|1|0.0|2875|mmu:18616|SCAN domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0006139//nucleobase-containing compound metabolic process;GO:0010467//gene expression;GO:0012501//programmed cell death;GO:0040007//growth gi|33438255|dbj|BAC65520.2|/0/mKIAA0287 protein [Mus musculus] 78403 1344 0.263333333 0.28 0.088536675 Up 0.097991651 2900041M22Rik RIKEN cDNA 2900041M22 gene - - - - - 12121 9591 0.313333333 0.333333333 0.089267338 Up 0.097991651 Bicd1 bicaudal D homolog 1 (Drosophila) K18739|1|0.0|1448|mmu:12121|protein bicaudal D GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0033648;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0033648;GO:0044444//cytoplasmic part "GO:0030674//protein binding, bridging;GO:0008092//cytoskeletal protein binding;GO:0017016//Ras GTPase binding;GO:0001664//G-protein coupled receptor binding;GO:0030674//protein binding, bridging;GO:0008092//cytoskeletal protein binding;GO:0017016//Ras GTPase binding;GO:0001664//G-protein coupled receptor binding" GO:0006898//receptor-mediated endocytosis;GO:0022618//ribonucleoprotein complex assembly;GO:0010519//negative regulation of phospholipase activity;GO:0044764;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0072384//organelle transport along microtubule;GO:0034453//microtubule anchoring;GO:0006898//receptor-mediated endocytosis;GO:0022618//ribonucleoprotein complex assembly;GO:0010519//negative regulation of phospholipase activity;GO:0044764;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0072384//organelle transport along microtubule;GO:0034453//microtubule anchoring gi|60360152|dbj|BAD90295.1|/0/mKIAA4125 protein [Mus musculus] 20983 3901 0.01 0.016666667 0.736965594 Up 0.097916432 Syt4 synaptotagmin IV K19904|1|0.0|791|mmu:20983|synaptotagmin-4 GO:0031224//intrinsic component of membrane;GO:0030141//secretory granule;GO:0008021//synaptic vesicle;GO:0042995//cell projection GO:0046872//metal ion binding;GO:0000149//SNARE binding;GO:0005543//phospholipid binding GO:0006906//vesicle fusion;GO:0017156//calcium ion regulated exocytosis;GO:0001505//regulation of neurotransmitter levels gi|60359940|dbj|BAD90189.1|/0/mKIAA1342 protein [Mus musculus] 80883 2190 0.016666667 0.026666667 0.678071905 Up 0.097916432 Ntng1 netrin G1 K07522|1|0.0|914|bacu:103019703|netrin-G1 - - - - 384059 3174 0.023333333 0.036666667 0.652076697 Up 0.097916432 Tlr12 toll-like receptor 12 K18807|1|0.0|1534|mmu:384059|toll-like receptor 12 GO:0031224//intrinsic component of membrane - GO:0045087//innate immune response;GO:0007165//signal transduction gi|45430001|ref|NP_991392.1|/0/toll-like receptor 12 precursor [Mus musculus] 13488 3543 0.02 0.033333333 0.736965594 Up 0.097916432 Drd1 dopamine receptor D1 K04144|1|0.0|848|mmu:13488|dopamine receptor D1 GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0044297//cell body;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0044297//cell body GO:0043169//cation binding;GO:0046983//protein dimerization activity;GO:0004952//dopamine neurotransmitter receptor activity;GO:0043169//cation binding;GO:0046983//protein dimerization activity;GO:0004952//dopamine neurotransmitter receptor activity "GO:0042754//negative regulation of circadian rhythm;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0021766//hippocampus development;GO:0071407//cellular response to organic cyclic compound;GO:0046475//glycerophospholipid catabolic process;GO:0032868//response to insulin;GO:0001964//startle response;GO:0048871//multicellular organismal homeostasis;GO:0007631//feeding behavior;GO:0014075//response to amine;GO:0019932//second-messenger-mediated signaling;GO:0021782//glial cell development;GO:0002209//behavioral defense response;GO:0015758//glucose transport;GO:0001508//action potential;GO:0045762//positive regulation of adenylate cyclase activity;GO:0035249//synaptic transmission, glutamatergic;GO:0001933//negative regulation of protein phosphorylation;GO:0014821;GO:0007618//mating;GO:0021544//subpallium development;GO:0008344//adult locomotory behavior;GO:0006886//intracellular protein transport;GO:0046958//nonassociative learning;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0021830//interneuron migration from the subpallium to the cortex;GO:0007632//visual behavior;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0042310//vasoconstriction;GO:0042069//regulation of catecholamine metabolic process;GO:0048168//regulation of neuronal synaptic plasticity;GO:0042754//negative regulation of circadian rhythm;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0021766//hippocampus development;GO:0071407//cellular response to organic cyclic compound;GO:0046475//glycerophospholipid catabolic process;GO:0032868//response to insulin;GO:0001964//startle response;GO:0048871//multicellular organismal homeostasis;GO:0007631//feeding behavior;GO:0014075//response to amine;GO:0019932//second-messenger-mediated signaling;GO:0021782//glial cell development;GO:0002209//behavioral defense response;GO:0015758//glucose transport;GO:0001508//action potential;GO:0045762//positive regulation of adenylate cyclase activity;GO:0035249//synaptic transmission, glutamatergic;GO:0001933//negative regulation of protein phosphorylation;GO:0014821;GO:0007618//mating;GO:0021544//subpallium development;GO:0008344//adult locomotory behavior;GO:0006886//intracellular protein transport;GO:0046958//nonassociative learning;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0021830//interneuron migration from the subpallium to the cortex;GO:0007632//visual behavior;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0042310//vasoconstriction;GO:0042069//regulation of catecholamine metabolic process;GO:0048168//regulation of neuronal synaptic plasticity" gi|33859542|ref|NP_034206.1|/0/D(1A) dopamine receptor [Mus musculus] 235379 4649 0.016666667 0.01 -0.736965594 Down 0.097916432 Gldn gliomedin K16364|1|0.0|944|mmu:235379|GLDN; gliomedin - - - - 22239 3599 0.01 0.016666667 0.736965594 Up 0.097916432 Ugt8a UDP galactosyltransferase 8A K04628|1|0.0|1102|mmu:22239|2-hydroxyacylsphingosine 1-beta-galactosyltransferase [EC:2.4.1.45] GO:0031224//intrinsic component of membrane GO:0035251//UDP-glucosyltransferase activity;GO:0035250//UDP-galactosyltransferase activity GO:0008366//axon ensheathment;GO:0007043//cell-cell junction assembly;GO:0006996//organelle organization;GO:0031175//neuron projection development;GO:0006681//galactosylceramide metabolic process;GO:0034613//cellular protein localization;GO:0010970//transport along microtubule gi|31543926|ref|NP_035804.2|/0/2-hydroxyacylsphingosine 1-beta-galactosyltransferase precursor [Mus musculus] 100043757 9807 0.016666667 0.01 -0.736965594 Down 0.097916432 Zfp831 zinc finger protein 831 K09239|1|2e-45|189|ocu:100338658|human immunodeficiency virus type I enhancer-binding protein - - - gi|150010581|ref|NP_001092798.1|/0/zinc finger protein 831 [Mus musculus] 330671 3105 0.036666667 0.023333333 -0.652076697 Down 0.097916432 B4galnt4 "beta-1,4-N-acetyl-galactosaminyl transferase 4" "K09657|1|0.0|1837|mmu:330671|beta-1,4-N-acetylgalactosaminyltransferase 4 [EC:2.4.1.244]" - - - - 241201 4846 0.016666667 0.01 -0.736965594 Down 0.097916432 Cdh7 "cadherin 7, type 2" "K06799|1|0.0|1413|mmu:241201|cadherin 7, type 2" - - - - 13799 3537 0.02 0.033333333 0.736965594 Up 0.097916432 En2 engrailed 2 K09319|1|6e-119|431|mmu:13799|homeobox protein engrailed GO:0043231//intracellular membrane-bounded organelle - GO:0007420//brain development;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter gi|6753752|ref|NP_034264.1|/4.98525e-118/homeobox protein engrailed-2 [Mus musculus] 634882 4374 0.016666667 0.01 -0.736965594 Down 0.097916432 Itih5l-ps "inter-alpha (globulin) inhibitor H5-like, pseudogene" K19015|1|1e-99|368|ocu:100009345|inter-alpha-trypsin inhibitor heavy chain H2 - - - gi|568904141|ref|XP_006544683.1|/0/PREDICTED: LOW QUALITY PROTEIN: inter-alpha-trypsin inhibitor heavy chain H6 [Mus musculus] 67928 5384 0.016666667 0.01 -0.736965594 Down 0.097916432 Abca14 "ATP-binding cassette, sub-family A (ABC1), member 14" "K05643|1|0.0|1490|mdo:100013281|ATP-binding cassette, subfamily A (ABC1), member 3" - - - "gi|157057142|ref|NP_080734.3|/0/ATP-binding cassette, sub-family A (ABC1), member 14 [Mus musculus] " 210417 6283 0.03 0.02 -0.584962501 Down 0.097916432 Thsd7b "thrombospondin, type I, domain containing 7B" K08624|1|3e-53|214|sko:100370521|a disintegrin and metalloproteinase with thrombospondin motifs 9 [EC:3.4.24.-] GO:0031224//intrinsic component of membrane - - gi|40254219|ref|NP_766073.2|/0/thrombospondin type-1 domain-containing protein 7B precursor [Mus musculus] 210162 4584 0.03 0.016666667 -0.847996907 Down 0.097916432 Zkscan2 zinc finger with KRAB and SCAN domains 2 K09229|1|0.0|1882|mmu:210162|KRAB and SCAN domains-containing zinc finger protein - - - gi|124486745|ref|NP_001074798.1|/0/zinc finger protein with KRAB and SCAN domains 2 [Mus musculus] 230806 4781 0.016666667 0.01 -0.736965594 Down 0.097916432 Aim1l absent in melanoma 1-like K16810|1|1e-20|105|bacu:103015945|TBCC domain-containing protein 1 - - - gi|568930994|ref|XP_006538811.1|/0/PREDICTED: absent in melanoma 1-like protein isoform X2 [Mus musculus] 14580 2600 0.023333333 0.036666667 0.652076697 Up 0.097916432 Gfap glial fibrillary acidic protein K05640|1|0.0|801|mmu:14580|glial fibrillary acidic protein GO:0044424;GO:0043234//protein complex;GO:0097386//glial cell projection;GO:0044424;GO:0043234//protein complex;GO:0097386//glial cell projection GO:0005198//structural molecule activity;GO:0019899//enzyme binding;GO:0005198//structural molecule activity;GO:0019899//enzyme binding GO:0048167//regulation of synaptic plasticity;GO:0010975//regulation of neuron projection development;GO:0045104//intermediate filament cytoskeleton organization;GO:0010624;GO:0008284//positive regulation of cell proliferation;GO:0001504//neurotransmitter uptake;GO:0033554//cellular response to stress;GO:0043062//extracellular structure organization;GO:0021782//glial cell development;GO:0048708//astrocyte differentiation;GO:0048167//regulation of synaptic plasticity;GO:0010975//regulation of neuron projection development;GO:0045104//intermediate filament cytoskeleton organization;GO:0010624;GO:0008284//positive regulation of cell proliferation;GO:0001504//neurotransmitter uptake;GO:0033554//cellular response to stress;GO:0043062//extracellular structure organization;GO:0021782//glial cell development;GO:0048708//astrocyte differentiation gi|84000448|ref|NP_034407.2|/0/glial fibrillary acidic protein isoform 2 [Mus musculus] 100503759 3604 0.02 0.03 0.584962501 Up 0.097916432 Gm5084 predicted gene 5084 - - - - "gi|148709350|gb|EDL41296.1|/1.27479e-60/hypothetical protein A030007L22, partial [Mus musculus]" 230735 5186 0.016666667 0.01 -0.736965594 Down 0.097916432 Epha10 Eph receptor A10 K08897|1|0.0|1761|mcc:100426059|Eph receptor A10 [EC:2.7.10.1] GO:0016021//integral component of membrane GO:0032550;GO:0005003//ephrin receptor activity GO:0006464//cellular protein modification process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006796//phosphate-containing compound metabolic process gi|374093225|ref|NP_001243361.1|/0/ephrin type-A receptor 10 isoform 1 precursor [Mus musculus] 627488 1217 0.016666667 0.01 -0.736965594 Down 0.097916432 Gm6763 predicted gene 6763 K12881|1|1e-129|465|mmu:100043292|THO complex subunit 4 GO:0005681//spliceosomal complex GO:0043566//structure-specific DNA binding GO:0006406//mRNA export from nucleus gi|397174787|ref|NP_001257571.1|/1.94041e-130/RNA and export factor-binding protein 2-like [Mus musculus] 627872 12272 0.01 0.016666667 0.736965594 Up 0.097916432 Dnah7a "dynein, axonemal, heavy chain 7A" "K10408|1|0.0|7802|mmu:627872|dynein heavy chain, axonemal" - - - "gi|354983491|ref|NP_001238999.1|/0/dynein, axonemal, heavy chain 7A [Mus musculus]" 667692 1217 0.016666667 0.01 -0.736965594 Down 0.097916432 Gm8764 predicted gene 8764 K12881|1|1e-129|465|mmu:100043292|THO complex subunit 4 GO:0005681//spliceosomal complex GO:0043566//structure-specific DNA binding GO:0006406//mRNA export from nucleus gi|397174787|ref|NP_001257571.1|/1.94041e-130/RNA and export factor-binding protein 2-like [Mus musculus] 94229 5421.22 0.01 0.016666667 0.736965594 Up 0.097916432 Slc4a10 "solute carrier family 4, sodium bicarbonate cotransporter-like, member 10" "K13861|1|0.0|2039|ngi:103744089|solute carrier family 4 (sodium bicarbonate transporter), member 10" GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459 GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity;GO:0015301//anion:anion antiporter activity GO:0006464//cellular protein modification process;GO:0055067;GO:0030001//metal ion transport;GO:0006464//cellular protein modification process;GO:0055067;GO:0030001//metal ion transport;GO:0006464//cellular protein modification process;GO:0055067;GO:0030001//metal ion transport;GO:0006464//cellular protein modification process;GO:0055067;GO:0030001//metal ion transport;GO:0006464//cellular protein modification process;GO:0055067;GO:0030001//metal ion transport;GO:0006464//cellular protein modification process;GO:0055067;GO:0030001//metal ion transport;GO:0006464//cellular protein modification process;GO:0055067;GO:0030001//metal ion transport gi|334688860|ref|NP_001229311.1|/0/sodium-driven chloride bicarbonate exchanger isoform 6 [Mus musculus] 75050 4462 0.01 0.016666667 0.736965594 Up 0.097916432 Kif27 kinesin family member 27 K10395|1|0.0|2583|mmu:75050|kinesin family member 4/21/27 GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton GO:0032550;GO:0003774//motor activity GO:0003341//cilium movement;GO:0007420//brain development;GO:0010927 gi|32401469|ref|NP_780423.2|/0/kinesin-like protein KIF27 [Mus musculus] 105439 2757 0.026666667 0.04 0.584962501 Up 0.097916432 Slain1 "SLAIN motif family, member 1" K16580|1|0.0|692|mmu:105439|SLAIN motif-containing protein 1/2 - - - gi|51491882|ref|NP_932131.2|/0/SLAIN motif-containing protein 1 [Mus musculus] 94047 4885 0.016666667 0.01 -0.736965594 Down 0.097916432 Cecr6 "cat eye syndrome chromosome region, candidate 6" - - - - gi|15808998|ref|NP_291045.1|/2.60051e-136/cat eye syndrome critical region protein 6 homolog [Mus musculus] 258513 3915 0.026666667 0.016666667 -0.678071905 Down 0.097916432 Olfr536 olfactory receptor 536 K04257|1|6e-163|578|mmu:258513|olfactory receptor GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007608//sensory perception of smell "gi|148685987|gb|EDL17934.1|/4.49589e-168/olfactory receptor 536, partial [Mus musculus]" 245450 7754 0.013333333 0.02 0.584962501 Up 0.097916432 Slitrk2 "SLIT and NTRK-like family, member 2" K06850|1|4e-21|107|dre:80354|slit 3 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0048667//cell morphogenesis involved in neuron differentiation gi|238637334|ref|NP_942563.2|/0/SLIT and NTRK-like protein 2 precursor [Mus musculus] 545861 4643 0.016666667 0.01 -0.736965594 Down 0.097916432 Gm5878 predicted gene 5878 K08798|1|8e-34|92.8|cge:100762996|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] - - - gi|133778971|ref|NP_001030074.2|/2.60446e-53/uncharacterized protein LOC545861 [Mus musculus] 241727 4543 0.01 0.016666667 0.736965594 Up 0.097916432 Snph syntaphilin K02599|1|3e-60|237|chx:102177020|Notch - - - - 333564 4830 0.01 0.016666667 0.736965594 Up 0.097916432 Fndc3c1 fibronectin type III domain containing 3C1 K12567|1|6e-40|169|sko:100367089|titin [EC:2.7.11.1] GO:0031224//intrinsic component of membrane - - gi|56090556|ref|NP_001007581.1|/0/fibronectin type III domain containing protein 3C1 [Mus musculus] 269109 4648 0.016666667 0.01 -0.736965594 Down 0.097916432 Dpp10 dipeptidylpeptidase 10 K01278|1|4e-133|479|obi:106877900|dipeptidyl-peptidase 4 [EC:3.4.14.5] - - - - 632671 2385 0.026666667 0.04 0.584962501 Up 0.097916432 Vmn2r18 "vomeronasal 2, receptor 18" K04613|1|0.0|1568|mmu:632671|vomeronasal 2 receptor;K04612|2|0.0|741|cge:100756752|calcium-sensing receptor - - - "gi|156938267|ref|NP_001096052.1|/0/vomeronasal 2, receptor 18 [Mus musculus]" 78212 3261 0.033333333 0.02 -0.736965594 Down 0.097916432 Rbm46os "RNA binding motif protein 46, opposite strand" - - - - "gi|148683479|gb|EDL15426.1|/3.31139e-52/mCG1032384, partial [Mus musculus]" 76389 4491 0.01 0.016666667 0.736965594 Up 0.097916432 Ankrd36 ankyrin repeat domain 36 K17299|1|0.0|2785|mmu:76389|POTE ankyrin domain family protein - - - gi|125628652|ref|NP_076305.2|/0/ankyrin repeat domain 36 [Mus musculus] 14786 2413 0.026666667 0.04 0.584962501 Up 0.097916432 Grb7 growth factor receptor bound protein 7 K20064|1|5e-157|557|lcm:102352775|growth factor receptor-bound protein 10 GO:0035770//ribonucleoprotein granule;GO:0005924//cell-substrate adherens junction;GO:0044444//cytoplasmic part;GO:0016020//membrane "GO:0030674//protein binding, bridging;GO:0019900//kinase binding;GO:0005543//phospholipid binding" GO:0016477//cell migration;GO:0006412//translation;GO:0022618//ribonucleoprotein complex assembly;GO:0007154//cell communication gi|6754066|ref|NP_034476.1|/0/growth factor receptor-bound protein 7 [Mus musculus] 30060 4133 0.016666667 0.01 -0.736965594 Down 0.097916432 Mfi2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 K06569|1|0.0|1464|mmu:30060|melanoma-associated antigen p97 GO:0031224//intrinsic component of membrane GO:0005506//iron ion binding GO:0000041//transition metal ion transport;GO:0006875//cellular metal ion homeostasis gi|13994140|ref|NP_038928.1|/0/melanotransferrin precursor [Mus musculus] 268491 4577 0.026666667 0.016666667 -0.678071905 Down 0.097916432 Meioc meiosis specific with coiled-coil domain - - - - gi|189011710|ref|NP_001121048.1|/0/meiosis-specific coiled-coil domain-containing protein MEIOC [Mus musculus] 225004 5085 0.023333333 0.013333333 -0.807354922 Down 0.097916432 BC027072 cDNA sequence BC027072 - GO:0043231//intracellular membrane-bounded organelle - GO:0050953//sensory perception of light stimulus gi|40254190|ref|NP_666194.2|/0/uncharacterized protein C2orf71 homolog [Mus musculus] 100861668 2514 0.026666667 0.016666667 -0.678071905 Down 0.097916432 Gm21119 "predicted gene, 21119" K17299|1|0.0|644|mmu:100861668|POTE ankyrin domain family protein - - - gi|395627657|ref|NP_001257482.1|/0/ankyrin repeat domain-containing protein 7-like [Mus musculus] 380701 2377 0.026666667 0.04 0.584962501 Up 0.097916432 Slc47a2 "solute carrier family 47, member 2" "K03327|1|0.0|995|mmu:380701|multidrug resistance protein, MATE family" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0015893//drug transport;GO:0044763 gi|85702045|ref|NP_001028714.1|/0/multidrug and toxin extrusion protein 2 [Mus musculus] 21990 4270 0.01 0.016666667 0.736965594 Up 0.097916432 Tph1 tryptophan hydroxylase 1 K00502|1|0.0|907|mmu:21990|tryptophan 5-monooxygenase [EC:1.14.16.4] GO:0042995//cell projection;GO:0044424;GO:0042995//cell projection;GO:0044424;GO:0042995//cell projection;GO:0044424 "GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen;GO:0046914//transition metal ion binding;GO:0031406//carboxylic acid binding;GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen;GO:0046914//transition metal ion binding;GO:0031406//carboxylic acid binding;GO:0016714//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen;GO:0046914//transition metal ion binding;GO:0031406//carboxylic acid binding" GO:0001503//ossification;GO:0042428//serotonin metabolic process;GO:0048771//tissue remodeling;GO:0048511//rhythmic process;GO:0006568//tryptophan metabolic process;GO:0044767//single-organism developmental process;GO:0006950//response to stress;GO:0001503//ossification;GO:0042428//serotonin metabolic process;GO:0048771//tissue remodeling;GO:0048511//rhythmic process;GO:0006568//tryptophan metabolic process;GO:0044767//single-organism developmental process;GO:0006950//response to stress;GO:0001503//ossification;GO:0042428//serotonin metabolic process;GO:0048771//tissue remodeling;GO:0048511//rhythmic process;GO:0006568//tryptophan metabolic process;GO:0044767//single-organism developmental process;GO:0006950//response to stress gi|444909167|ref|NP_001263301.1|/9.6148e-83/tryptophan 5-hydroxylase 1 isoform 2 [Mus musculus] 210108 5007 0.01 0.016666667 0.736965594 Up 0.097916432 D130043K22Rik RIKEN cDNA D130043K22 gene K15619|1|2e-10|71.6|cmy:102932118|Kunitz-type protease inhibitor 1 GO:0031224//intrinsic component of membrane;GO:0005769//early endosome - GO:0016477//cell migration;GO:0010977//negative regulation of neuron projection development gi|124486676|ref|NP_001074520.1|/0/dyslexia-associated protein KIAA0319 homolog precursor [Mus musculus] 246313 4533 0.016666667 0.01 -0.736965594 Down 0.097916432 Prokr2 prokineticin receptor 2 K08380|1|0.0|765|rno:192649|prokineticin receptor 2 GO:0031224//intrinsic component of membrane GO:0008188//neuropeptide receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0048511//rhythmic process "gi|149023368|gb|EDL80262.1|/0/prokineticin receptor 2, isoform CRA_a [Rattus norvegicus]" 270711 3714 0.01 0.016666667 0.736965594 Up 0.097916432 Fam26d "family with sequence similarity 26, member D" K19739|1|8e-31|139|amj:102576951|calcium homeostasis modulator protein 2 GO:0031224//intrinsic component of membrane - - gi|26324706|dbj|BAC26107.1|/1.2765e-172/unnamed protein product [Mus musculus] 56087 14038 0.01 0.016666667 0.736965594 Up 0.097916432 Dnah10 "dynein, axonemal, heavy chain 10" "K10408|1|0.0|8828|mmu:56087|dynein heavy chain, axonemal" - - - "gi|254692843|ref|NP_062409.1|/0/dynein heavy chain 10, axonemal [Mus musculus]" 20273 11241 0.016666667 0.01 -0.736965594 Down 0.097916432 Scn8a "sodium channel, voltage-gated, type VIII, alpha" K04840|1|0.0|3398|mmu:20273|voltage-gated sodium channel type VIII alpha - - - - 22062 4468 0.01 0.016666667 0.736965594 Up 0.097916432 Trp73 transformation related protein 73 K10148|1|0.0|1279|mmu:22062|tumor protein p73 - - - gi|537222658|gb|ERE82728.1|/0/tumor protein [Cricetulus griseus] 231014 4627 0.016666667 0.01 -0.736965594 Down 0.097916432 9330182L06Rik RIKEN cDNA 9330182L06 gene K17495|1|2e-07|61.6|bfo:BRAFLDRAFT_118457|CUB and sushi domain-containing protein GO:0031224//intrinsic component of membrane - - "gi|148682749|gb|EDL14696.1|/0/RIKEN cDNA 9330182L06, isoform CRA_c, partial [Mus musculus]" 12824 4944 0.016666667 0.01 -0.736965594 Down 0.097916432 Col2a1 "collagen, type II, alpha 1" "K19719|1|6e-155|551|mmu:12824|collagen, type II, alpha" - - - - 18423 2842 0.026666667 0.04 0.584962501 Up 0.097916432 Otx1 orthodenticle homeobox 1 K09326|1|8e-113|410|mmu:18423|homeobox protein OTX1 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0003002//regionalization;GO:0042471//ear morphogenesis;GO:0030902//hindbrain development;GO:0006366//transcription from RNA polymerase II promoter gi|25168269|ref|NP_035153.1|/7.09317e-112/homeobox protein OTX1 [Mus musculus] 637004 2670 0.023333333 0.036666667 0.652076697 Up 0.097916432 Vmn2r3 "vomeronasal 2, receptor 3" K04613|1|0.0|1427|rno:295090|vomeronasal 2 receptor GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0010033//response to organic substance "gi|157277944|ref|NP_001098084.1|/0/vomeronasal 2, receptor 3 [Mus musculus]" 320158 4206 0.016666667 0.026666667 0.678071905 Up 0.097916432 Zmat4 "zinc finger, matrin type 4" "K10137|1|3e-09|67.4|pbi:103050289|zinc finger, matrin type 3" GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding - gi|568954134|ref|XP_006509202.1|/9.96132e-121/PREDICTED: zinc finger matrin-type protein 4 isoform X2 [Mus musculus] 327814 6451.27 0.033333333 0.02 -0.736965594 Down 0.097916432 Ppfia2 "protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2" K20283|1|4e-16|91.3|mde:101892550|golgin subfamily A member 4 - - - - 70737 5015 0.016666667 0.01 -0.736965594 Down 0.097916432 Cgn cingulin K06102|1|0.0|1866|mmu:70737|cingulin GO:0043296//apical junction complex;GO:0043296//apical junction complex GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway gi|50510881|dbj|BAD32426.1|/0/mKIAA1319 protein [Mus musculus] 14811 4512 0.01 0.016666667 0.736965594 Up 0.097916432 Grin2a "glutamate receptor, ionotropic, NMDA2A (epsilon 1)" "K05209|1|0.0|2949|mmu:14811|glutamate receptor ionotropic, NMDA 2A" GO:0033267;GO:0008328//ionotropic glutamate receptor complex;GO:0044327//dendritic spine head;GO:0030136//clathrin-coated vesicle;GO:0030313//cell envelope;GO:0097060//synaptic membrane GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0005102//receptor binding;GO:0019900//kinase binding;GO:0005261//cation channel activity;GO:0004970//ionotropic glutamate receptor activity;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0016597//amino acid binding;GO:0005244//voltage-gated ion channel activity GO:0009636//response to toxic substance;GO:0006915//apoptotic process;GO:0009607//response to biotic stimulus;GO:0014075//response to amine;GO:0007215//glutamate receptor signaling pathway;GO:0051899//membrane depolarization;GO:0021543//pallium development;GO:0019233//sensory perception of pain;GO:0043331//response to dsRNA;GO:0007611//learning or memory;GO:0009895;GO:0010043//response to zinc ion;GO:0043200//response to amino acid;GO:0033993//response to lipid;GO:0009605//response to external stimulus;GO:0032026//response to magnesium ion;GO:0010042//response to manganese ion;GO:0070848//response to growth factor;GO:0006584//catecholamine metabolic process;GO:0007632//visual behavior;GO:0051259//protein oligomerization;GO:0040011//locomotion;GO:0006950//response to stress;GO:0033036;GO:0045838//positive regulation of membrane potential;GO:0006816//calcium ion transport;GO:0042430//indole-containing compound metabolic process;GO:0097305//response to alcohol;GO:0048168//regulation of neuronal synaptic plasticity "gi|41680705|ref|NP_032196.2|/0/glutamate receptor ionotropic, NMDA 2A precursor [Mus musculus]" 171211 8103 0.013333333 0.02 0.584962501 Up 0.097916432 Edaradd EDAR (ectodysplasin-A receptor)-associated death domain - GO:0044424 GO:0032813//tumor necrosis factor receptor superfamily binding GO:0042476//odontogenesis;GO:0008544//epidermis development;GO:0048732//gland development;GO:0048869//cellular developmental process gi|127139913|ref|NP_598398.3|/1.93952e-115/ectodysplasin-A receptor-associated adapter protein isoform 1 [Mus musculus] 20538 6073 0.036666667 0.023333333 -0.652076697 Down 0.097916432 Slc6a2 "solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2" "K05035|1|0.0|1201|mmu:20538|solute carrier family 6 (neurotransmitter transporter, noradrenalin) member 2" GO:0016021//integral component of membrane;GO:0042995//cell projection GO:0005328//neurotransmitter:sodium symporter activity;GO:0008504//monoamine transmembrane transporter activity;GO:0015631//tubulin binding GO:0051937;GO:0007267//cell-cell signaling;GO:0042221//response to chemical;GO:0033555//multicellular organismal response to stress gi|568956380|ref|XP_006530856.1|/0/PREDICTED: sodium-dependent noradrenaline transporter isoform X1 [Mus musculus] 76464 6525 0.013333333 0.02 0.584962501 Up 0.097916432 Casc5 cancer susceptibility candidate 5 K11542|1|0.0|3967|mmu:76464|protein CASC5 - - - gi|125628638|ref|NP_083893.2|/0/protein CASC5 [Mus musculus] 14829 2582 0.016666667 0.01 -0.736965594 Down 0.097916432 Grpr gastrin releasing peptide receptor K04169|1|0.0|721|mmu:14829|gastrin-releasing peptide receptor GO:0031224//intrinsic component of membrane GO:0008188//neuropeptide receptor activity;GO:0042277//peptide binding GO:0051705;GO:0044708//single-organism behavior;GO:0008283//cell proliferation;GO:0007267//cell-cell signaling;GO:0007186//G-protein coupled receptor signaling pathway gi|6680111|ref|NP_032203.1|/0/gastrin-releasing peptide receptor [Mus musculus] 12550 4447 0.01 0.016666667 0.736965594 Up 0.097916432 Cdh1 cadherin 1 "K05689|1|0.0|1559|mmu:12550|cadherin 1, type 1, E-cadherin" - - - - 170711 3461 0.02 0.033333333 0.736965594 Up 0.097916432 Otud7a OTU domain containing 7A K11860|1|0.0|1415|mmu:170711|OTU domain-containing protein 7 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process gi|18700018|ref|NP_570950.1|/0/OTU domain-containing protein 7A [Mus musculus] 242819 3700 0.02 0.03 0.584962501 Up 0.097916432 Rundc3b RUN domain containing 3B "K05659|1|1e-45|188|oas:101122517|ATP-binding cassette, subfamily B (MDR/TAP), member 4 [EC:3.6.3.44];K12482|3|3e-24|117|mze:101470260|RUN and FYVE domain-containing protein 1" - - - gi|39930589|ref|NP_941022.1|/0/RUN domain-containing protein 3B [Mus musculus] 258693 4361 0.01 0.016666667 0.736965594 Up 0.097916432 Olfr1443 olfactory receptor 1443 K04257|1|1e-153|547|mmu:258693|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|22129441|ref|NP_666909.1|/1.02812e-152/olfactory receptor 1443 [Mus musculus] 666060 4827 0.03 0.016666667 -0.847996907 Down 0.097916432 Frmpd1 FERM and PDZ domain containing 1 K05725|1|5e-15|87.0|lgi:LOTGIDRAFT_120690|focal adhesion kinase 1 [EC:2.7.10.2];K00940|4|2e-10|71.6|hmg:100201058|nucleoside-diphosphate kinase [EC:2.7.4.6] GO:0016020//membrane;GO:0043232 - GO:0007154//cell communication gi|124487185|ref|NP_001074641.1|/0/FERM and PDZ domain-containing protein 1 [Mus musculus] 319767 6926 0.02 0.033333333 0.736965594 Up 0.097916432 Atp10b "ATPase, class V, type 10B" K01530|1|0.0|2830|mmu:319767|phospholipid-translocating ATPase [EC:3.6.3.1] - - - gi|125628644|ref|NP_795973.2|/0/probable phospholipid-transporting ATPase VB [Mus musculus] 11519 8006 0.026666667 0.016666667 -0.678071905 Down 0.097916432 Add2 adducin 2 (beta) K18622|1|0.0|1067|mmu:11519|adducin GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0015629//actin cytoskeleton;GO:0016020//membrane GO:0043169//cation binding;GO:0042802//identical protein binding;GO:0003779//actin binding;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0042802//identical protein binding;GO:0003779//actin binding;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0042802//identical protein binding;GO:0003779//actin binding;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0042802//identical protein binding;GO:0003779//actin binding;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0042802//identical protein binding;GO:0003779//actin binding;GO:0046983//protein dimerization activity;GO:0005198//structural molecule activity;GO:0043169//cation binding;GO:0042802//identical protein binding;GO:0003779//actin binding;GO:0046983//protein dimerization activity;GO:0005198//structural molecule activity GO:0048534//hematopoietic or lymphoid organ development;GO:0043393//regulation of protein binding;GO:0044765//single-organism transport;GO:0051693//actin filament capping;GO:0048534//hematopoietic or lymphoid organ development;GO:0043393//regulation of protein binding;GO:0044765//single-organism transport;GO:0051693//actin filament capping;GO:0048534//hematopoietic or lymphoid organ development;GO:0043393//regulation of protein binding;GO:0044765//single-organism transport;GO:0051693//actin filament capping;GO:0048534//hematopoietic or lymphoid organ development;GO:0043393//regulation of protein binding;GO:0044765//single-organism transport;GO:0051693//actin filament capping;GO:0048534//hematopoietic or lymphoid organ development;GO:0043393//regulation of protein binding;GO:0044765//single-organism transport;GO:0051693//actin filament capping;GO:0048534//hematopoietic or lymphoid organ development;GO:0043393//regulation of protein binding;GO:0044765//single-organism transport;GO:0051693//actin filament capping gi|31560504|ref|NP_038486.2|/0/beta-adducin isoform 1 [Mus musculus] 100313531 4345 0.01 0.016666667 0.736965594 Up 0.097916432 Nkx2-2os "NK2 homeobox 2, opposite strand" K08029|1|1e-45|188|aam:106499582|homeobox protein Nkx-2.2 GO:0031981//nuclear lumen GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding GO:0007166//cell surface receptor signaling pathway;GO:0048664//neuron fate determination;GO:0021529//spinal cord oligodendrocyte cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0003312;GO:0003310//pancreatic A cell differentiation;GO:0001708//cell fate specification;GO:0045687//positive regulation of glial cell differentiation;GO:0003309//type B pancreatic cell differentiation;GO:0044093;GO:0021782//glial cell development "gi|148696575|gb|EDL28522.1|/1.04738e-72/mCG146261, partial [Mus musculus]" 14763 3205 0.023333333 0.036666667 0.652076697 Up 0.097916432 Gpr37 G protein-coupled receptor 37 K04243|1|0.0|1112|mmu:14763|G protein-coupled receptor 37 (endothelin receptor type B-like) GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|160298211|ref|NP_034468.2|/0/prosaposin receptor GPR37 precursor [Mus musculus] 71775 2275 0.026666667 0.04 0.584962501 Up 0.097916432 1300017J02Rik RIKEN cDNA 1300017J02 gene K14736|1|0.0|1415|mmu:71775|transferrin - GO:0005506//iron ion binding GO:0000041//transition metal ion transport;GO:0044092//negative regulation of molecular function;GO:0006875//cellular metal ion homeostasis gi|21313642|ref|NP_082194.1|/0/inhibitor of carbonic anhydrase precursor [Mus musculus] 224224 6992 0.023333333 0.036666667 0.652076697 Up 0.097916432 Impg2 interphotoreceptor matrix proteoglycan 2 K19017|1|0.0|2299|mmu:224224|interphotoreceptor matrix proteoglycan 2 GO:0031224//intrinsic component of membrane;GO:0031012//extracellular matrix GO:0005539//glycosaminoglycan binding - "gi|148665738|gb|EDK98154.1|/0/interphotoreceptor matrix proteoglycan 2, isoform CRA_a [Mus musculus]" 239134 2672 0.023333333 0.036666667 0.652076697 Up 0.097916432 Gucy1b2 "guanylate cyclase 1, soluble, beta 2" K12319|1|0.0|1608|mmu:239134|guanylate cyclase soluble subunit beta [EC:4.6.1.2] - - - gi|324120991|ref|NP_001191269.1|/0/guanylate cyclase soluble subunit beta-2 isoform 2 [Mus musculus] 432879 2982 0.026666667 0.04 0.584962501 Up 0.097916432 Kbtbd6 kelch repeat and BTB (POZ) domain containing 6 K10474|1|0.0|912|mmu:432879|kelch repeat and BTB domain-containing protein 6/7 - - - - 330790 3576 0.02 0.033333333 0.736965594 Up 0.097916432 Hapln4 hyaluronan and proteoglycan link protein 4 K06853|1|0.0|650|mmu:330790|hyaluronan and proteoglycan link protein 4 GO:0031012//extracellular matrix - GO:0022610 "gi|148696832|gb|EDL28779.1|/0/hyaluronan and proteoglycan link protein 4, partial [Mus musculus]" 238662 4281 0.016666667 0.01 -0.736965594 Down 0.097916432 Spata31d1b "spermatogenesis associated 31 subfamily D, member 1B" - - - - gi|263197426|ref|NP_001161065.1|/0/uncharacterized protein LOC238662 [Mus musculus] 320277 4247 0.01 0.016666667 0.736965594 Up 0.097916432 Spef2 sperm flagellar 2 - - - - - 74002 4548 0.01 0.016666667 0.736965594 Up 0.097916432 Psd2 pleckstrin and Sec7 domain containing 2 K12494|1|0.0|1303|mmu:74002|PH and SEC7 domain-containing protein - - - gi|575771869|ref|NP_001276531.1|/0/PH and SEC7 domain-containing protein 2 isoform 2 [Mus musculus] 320696 3636 0.01 0.016666667 0.736965594 Up 0.097916432 Ccdc158 coiled-coil domain containing 158 K16464|1|4e-33|146|aam:106499931|centrosomal protein CEP250 - - - gi|28893281|ref|NP_796204.1|/0/coiled-coil domain-containing protein 158 [Mus musculus] 338372 10619 0.026666667 0.04 0.584962501 Up 0.097916432 Map3k9 mitogen-activated protein kinase kinase kinase 9 K04417|1|0.0|1077|mmu:338372|mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25] - - - - 231296 3116 0.023333333 0.036666667 0.652076697 Up 0.097916432 Lrrc66 leucine rich repeat containing 66 K13023|1|8e-11|72.4|oas:101106297|carboxypeptidase N regulatory subunit GO:0031224//intrinsic component of membrane - - gi|23956358|ref|NP_705796.1|/0/leucine-rich repeat-containing protein 66 [Mus musculus] 73936 2630 0.023333333 0.036666667 0.652076697 Up 0.097916432 Ccdc175 coiled-coil domain containing 175 K20283|1|8e-19|98.6|myd:102761577|golgin subfamily A member 4;K20478|4|2e-17|94.4|mde:101889747|golgin subfamily B member 1 - - - gi|256542283|ref|NP_082963.1|/0/coiled-coil domain-containing protein 175 [Mus musculus] 22095 4332 0.016666667 0.01 -0.736965594 Down 0.097916432 Tshr thyroid stimulating hormone receptor K04249|1|0.0|1438|mmu:22095|thyroid stimulating hormone receptor GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0016500//protein-hormone receptor activity;GO:0016500//protein-hormone receptor activity GO:0030098//lymphocyte differentiation;GO:0035264//multicellular organism growth;GO:0007626//locomotory behavior;GO:0040011//locomotion;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0030098//lymphocyte differentiation;GO:0035264//multicellular organism growth;GO:0007626//locomotory behavior;GO:0040011//locomotion;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway gi|62990176|ref|NP_035778.3|/0/thyrotropin receptor isoform 1 precursor [Mus musculus] 13512 4138 0.02 0.013333333 -0.584962501 Down 0.097916432 Dsg3 desmoglein 3 K07598|1|0.0|1845|mmu:13512|desmoglein 3 - - - - 73884 12571 0.01 0.016666667 0.736965594 Up 0.097916432 Zdbf2 "zinc finger, DBF-type containing 2" K06837|1|1e-15|90.5|clv:102086400|disintegrin and metalloproteinase domain-containing protein 23 [EC:3.4.24.-] - - - gi|255982598|ref|NP_082949.1|/0/DBF4-type zinc finger-containing protein 2 homolog isoform 1 [Mus musculus] 80979 4378 0.03 0.016666667 -0.847996907 Down 0.097916432 Slc26a5 "solute carrier family 26, member 5" "K14703|1|0.0|1370|mmu:80979|solute carrier family 26, member 5" GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459 GO:0008092//cytoskeletal protein binding;GO:0015103//inorganic anion transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0008092//cytoskeletal protein binding;GO:0015103//inorganic anion transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0008092//cytoskeletal protein binding;GO:0015103//inorganic anion transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0050954//sensory perception of mechanical stimulus;GO:0022604//regulation of cell morphogenesis;GO:0015698//inorganic anion transport;GO:0006873//cellular ion homeostasis;GO:0050954//sensory perception of mechanical stimulus;GO:0022604//regulation of cell morphogenesis;GO:0015698//inorganic anion transport;GO:0006873//cellular ion homeostasis;GO:0050954//sensory perception of mechanical stimulus;GO:0022604//regulation of cell morphogenesis;GO:0015698//inorganic anion transport;GO:0006873//cellular ion homeostasis gi|28933459|ref|NP_109652.3|/0/prestin isoform 1 [Mus musculus] 20451 6306 0.016666667 0.03 0.847996907 Up 0.097916432 St8sia3 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3" "K06613|1|0.0|757|tup:102500062|alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8C) [EC:2.4.99.-]" GO:0031228//intrinsic component of Golgi membrane GO:0008373//sialyltransferase activity GO:0001573//ganglioside metabolic process;GO:0006487//protein N-linked glycosylation "gi|62087572|dbj|BAD92233.1|/0/ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 variant [Homo sapiens]" 329844 3387 0.01 0.016666667 0.736965594 Up 0.097916432 C630028M04Rik RIKEN cDNA C630028M04 gene - - - - "gi|148702471|gb|EDL34418.1|/4.44739e-07/mCG1042149, partial [Mus musculus]" 83674 5056 0.023333333 0.013333333 -0.807354922 Down 0.097916432 Cnnm1 cyclin M1 K16302|1|0.0|1550|mmu:83674|metal transporter CNNM - - - gi|157412265|ref|NP_113573.2|/0/metal transporter CNNM1 [Mus musculus] 70638 4790 0.016666667 0.01 -0.736965594 Down 0.097916432 Fam189a1 "family with sequence similarity 189, member A1" - - - - gi|166795260|ref|NP_898910.2|/0/protein FAM189A1 [Mus musculus] 15378 4363 0.01 0.016666667 0.736965594 Up 0.097916432 Hnf4a "hepatic nuclear factor 4, alpha" K07292|1|0.0|858|mmu:15378|hepatocyte nuclear factor 4-alpha GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle "GO:0047617//acyl-CoA hydrolase activity;GO:0008289//lipid binding;GO:0008134//transcription factor binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0000975//regulatory region DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0046914//transition metal ion binding;GO:0047617//acyl-CoA hydrolase activity;GO:0008289//lipid binding;GO:0008134//transcription factor binding;GO:0038023//signaling receptor activity;GO:0042802//identical protein binding;GO:0000975//regulatory region DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0046914//transition metal ion binding" "GO:0006633//fatty acid biosynthetic process;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0007369//gastrulation;GO:0032846;GO:0003006//developmental process involved in reproduction;GO:0016049//cell growth;GO:0055090//acylglycerol homeostasis;GO:0001933//negative regulation of protein phosphorylation;GO:0030073//insulin secretion;GO:0048869//cellular developmental process;GO:0000060//protein import into nucleus, translocation;GO:0007599//hemostasis;GO:0033500//carbohydrate homeostasis;GO:0000278//mitotic cell cycle;GO:0046683//response to organophosphorus;GO:0044092//negative regulation of molecular function;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0034330;GO:0009755//hormone-mediated signaling pathway;GO:0006732;GO:1901605;GO:0009746;GO:0006094//gluconeogenesis;GO:0030033//microvillus assembly;GO:0006633//fatty acid biosynthetic process;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0007369//gastrulation;GO:0032846;GO:0003006//developmental process involved in reproduction;GO:0016049//cell growth;GO:0055090//acylglycerol homeostasis;GO:0001933//negative regulation of protein phosphorylation;GO:0030073//insulin secretion;GO:0048869//cellular developmental process;GO:0000060//protein import into nucleus, translocation;GO:0007599//hemostasis;GO:0033500//carbohydrate homeostasis;GO:0000278//mitotic cell cycle;GO:0044092//negative regulation of molecular function;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0034330;GO:0009755//hormone-mediated signaling pathway;GO:0006732;GO:1901605;GO:0009746;GO:0006094//gluconeogenesis;GO:0030033//microvillus assembly" gi|667294675|ref|XP_008578997.1|/0/PREDICTED: hepatocyte nuclear factor 4-alpha isoform X3 [Galeopterus variegatus] 100861880 1217 0.016666667 0.01 -0.736965594 Down 0.097916432 Gm21293 "predicted gene, 21293" K12881|1|1e-129|465|mmu:100043292|THO complex subunit 4 GO:0005681//spliceosomal complex GO:0043566//structure-specific DNA binding GO:0006406//mRNA export from nucleus gi|397174787|ref|NP_001257571.1|/1.94041e-130/RNA and export factor-binding protein 2-like [Mus musculus] 19023 2274 0.026666667 0.04 0.584962501 Up 0.097916432 Ppef2 "protein phosphatase, EF hand calcium-binding domain 2" K13807|1|0.0|1513|mmu:19023|serine/threonine-protein phosphatase with EF-hands [EC:3.1.3.16] GO:0031513//nonmotile primary cilium GO:0031072//heat shock protein binding;GO:0046914//transition metal ion binding;GO:0019901//protein kinase binding;GO:0004721//phosphoprotein phosphatase activity GO:0050953//sensory perception of light stimulus;GO:0001933//negative regulation of protein phosphorylation;GO:0043405//regulation of MAP kinase activity gi|6755140|ref|NP_035278.1|/0/serine/threonine-protein phosphatase with EF-hands 2 [Mus musculus] 80976 3751 0.02 0.033333333 0.736965594 Up 0.097916432 Syt13 synaptotagmin XIII K19913|1|0.0|703|mmu:80976|synaptotagmin-13 "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0016021//integral component of membrane" - GO:0006810//transport gi|14140242|ref|NP_109650.1|/0/synaptotagmin-13 [Mus musculus] 13109 3651 0.02 0.03 0.584962501 Up 0.097916432 Cyp2j5 "cytochrome P450, family 2, subfamily j, polypeptide 5" "K07418|1|0.0|987|mmu:13109|cytochrome P450, family 2, subfamily J [EC:1.14.14.1]" GO:0043231//intracellular membrane-bounded organelle "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0008392//arachidonic acid epoxygenase activity;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0016653//oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor" GO:0019369//arachidonic acid metabolic process;GO:0010033//response to organic substance gi|6753586|ref|NP_034137.1|/0/cytochrome P450 2J5 [Mus musculus] 241656 4773 0.016666667 0.01 -0.736965594 Down 0.097916432 Pak7 p21 protein (Cdc42/Rac)-activated kinase 7 K05736|1|0.0|1420|mmu:241656|p21-activated kinase 7 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004672//protein kinase activity GO:0006915//apoptotic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process gi|568917008|ref|XP_006499571.1|/0/PREDICTED: serine/threonine-protein kinase PAK 7 isoform X2 [Mus musculus] 242653 4236 0.01 0.016666667 0.736965594 Up 0.097916432 Cldn19 claudin 19 K06087|1|2e-125|450|mmu:242653|claudin GO:0043296//apical junction complex;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043296//apical junction complex;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0050877//neurological system process;GO:0007043//cell-cell junction assembly;GO:0050877//neurological system process;GO:0007043//cell-cell junction assembly gi|84370229|ref|NP_001033679.1|/1.61425e-124/claudin-19 isoform 1 [Mus musculus] 381522 5081 0.023333333 0.013333333 -0.807354922 Down 0.097916432 Ccdc180 coiled-coil domain containing 180 K00722|1|3e-47|194|mgp:100540036|globoside alpha-N-acetylgalactosaminyltransferase [EC:2.4.1.88];K20283|2|2e-08|65.5|cmy:102947438|golgin subfamily A member 4;K20478|3|4e-08|64.3|pbi:103068168|golgin subfamily B member 1;K10402|4|2e-07|62.0|ola:101173808|kinesin family member 20 - - - gi|295789102|ref|NP_941062.2|/0/coiled-coil domain-containing protein 180 [Mus musculus] 72393 4632 0.03 0.016666667 -0.847996907 Down 0.097916432 Faim2 Fas apoptotic inhibitory molecule 2 K07607|1|1e-153|547|ssc:100152434|peripherin;K06890|2|7e-69|265|bom:102271112|uncharacterized protein GO:0031224//intrinsic component of membrane;GO:0097060//synaptic membrane;GO:0031224//intrinsic component of membrane;GO:0097060//synaptic membrane - GO:0042981//regulation of apoptotic process;GO:0021533//cell differentiation in hindbrain;GO:0021695//cerebellar cortex development;GO:0042981//regulation of apoptotic process;GO:0021533//cell differentiation in hindbrain;GO:0021695//cerebellar cortex development gi|37360156|dbj|BAC98056.1|/2.70922e-167/mKIAA0950 protein [Mus musculus] 100861891 1217 0.016666667 0.01 -0.736965594 Down 0.097916432 Gm21304 "predicted gene, 21304" K12881|1|1e-129|465|mmu:100043292|THO complex subunit 4 GO:0005681//spliceosomal complex GO:0043566//structure-specific DNA binding GO:0006406//mRNA export from nucleus gi|397174787|ref|NP_001257571.1|/1.94041e-130/RNA and export factor-binding protein 2-like [Mus musculus] 71355 7135.05 0.016666667 0.01 -0.736965594 Down 0.097916432 Col24a1 "collagen, type XXIV, alpha 1" "K19721|1|0.0|2288|mmu:71355|collagen, type V/XI/XXIV/XXVII, alpha" - - - - 241159 4524 0.01 0.016666667 0.736965594 Up 0.097916432 Neu4 sialidase 4 K12357|1|0.0|978|mmu:241159|sialidase-2/3/4 [EC:3.2.1.18] GO:0031090//organelle membrane;GO:0000323//lytic vacuole GO:0004308//exo-alpha-sialidase activity - gi|894216196|ref|NP_001297698.1|/0/sialidase-4 isoform 1 [Mus musculus] 27062 5475.23 0.016666667 0.01 -0.736965594 Down 0.097916432 Cadps Ca2+-dependent secretion activator K19933|1|0.0|2385|aml:100471007|calcium-dependent secretion activator - - - gi|28972638|dbj|BAC65735.1|/0/mKIAA1121 protein [Mus musculus] 72077 4301 0.01 0.016666667 0.736965594 Up 0.097916432 Gcnt3 "glucosaminyl (N-acetyl) transferase 3, mucin type" "K09662|1|0.0|880|mmu:72077|N-acetylglucosaminyltransferase 3, mucin type [EC:2.4.1.-]" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0008375//acetylglucosaminyltransferase activity GO:0002381//immunoglobulin production involved in immunoglobulin mediated immune response;GO:0006486//protein glycosylation;GO:0001822//kidney development;GO:0009653//anatomical structure morphogenesis;GO:0022600//digestive system process "gi|124430729|ref|NP_082363.2|/0/beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 [Mus musculus]" 231470 15848 0.02 0.013333333 -0.584962501 Down 0.097916432 Fras1 Fraser extracellular matrix complex subunit 1 K08654|1|4e-107|394|cjo:107306216|proprotein convertase subtilisin/kexin type 5 [EC:3.4.21.-] - - - - 65112 4531 14.46666667 14.59333333 0.012576912 Up 0.097596751 Pmepa1 "prostate transmembrane protein, androgen induced 1" - - - - - 22214 4642.13 21.09666667 21.23 0.009089304 Up 0.097596751 Ube2h ubiquitin-conjugating enzyme E2H K10576|1|1e-77|295|phi:102108185|ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23] - GO:0019787//ubiquitin-like protein transferase activity;GO:0032550;GO:0019787//ubiquitin-like protein transferase activity;GO:0032550 GO:0019941//modification-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0019941//modification-dependent protein catabolic process;GO:0000209//protein polyubiquitination gi|585168963|ref|XP_006736538.1|/5.48082e-89/PREDICTED: ubiquitin-conjugating enzyme E2 H-like [Leptonychotes weddellii] 76987 2305.03 21.25 21.11666667 -0.009080723 Down 0.097596751 Hdhd2 haloacid dehalogenase-like hydrolase domain containing 2 K11725|1|9e-46|187|xma:102230340|phospholysine phosphohistidine inorganic pyrophosphate phosphatase [EC:3.6.1.1 3.1.3.-] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0043169//cation binding;GO:0003824//catalytic activity GO:0006915//apoptotic process;GO:0006915//apoptotic process gi|85861235|ref|NP_001034291.1|/1.09433e-58/haloacid dehalogenase-like hydrolase domain-containing protein 2 isoform 2 [Mus musculus] 98314 3266.14 17.17666667 17.04666667 -0.010960432 Down 0.097596751 D2hgdh D-2-hydroxyglutarate dehydrogenase K00102|1|6e-43|179|tup:102470164|D-lactate dehydrogenase (cytochrome) [EC:1.1.2.4] - "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding" GO:0019538//protein metabolic process;GO:0010038//response to metal ion;GO:0019538//protein metabolic process;GO:0010038//response to metal ion "gi|568909861|ref|XP_006530031.1|/0/PREDICTED: D-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X1 [Mus musculus]" 68350 3732 20.60666667 20.47333333 -0.009365142 Down 0.097596751 Mul1 mitochondrial ubiquitin ligase activator of NFKB 1 K15688|1|0.0|652|mmu:68350|E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27] GO:0042579//microbody;GO:0031306//intrinsic component of mitochondrial outer membrane GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0060089;GO:0019787//ubiquitin-like protein transferase activity GO:0051640//organelle localization;GO:0031647//regulation of protein stability;GO:0006915//apoptotic process;GO:0010822//positive regulation of mitochondrion organization;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0012502//induction of programmed cell death;GO:0008053//mitochondrial fusion;GO:0016925//protein sumoylation;GO:0016049//cell growth;GO:0000187//activation of MAPK activity gi|31541787|ref|NP_080965.2|/0/mitochondrial ubiquitin ligase activator of NFKB 1 [Mus musculus] 54636 1600.24 20.99333333 21.12666667 0.009133902 Up 0.097596751 Wdr45 WD repeat domain 45 K14810|1|7e-86|320|tsp:Tsp_06600|ATP-dependent RNA helicase DDX56/DBP9 [EC:3.6.4.13];K17908|2|4e-30|135|aqu:100634321|autophagy-related protein 18 - - - "gi|148701965|gb|EDL33912.1|/0/WD repeat domain 45, isoform CRA_b, partial [Mus musculus]" 71732 3194 13.13333333 13.26 0.013847646 Up 0.097596751 Vps11 "VPS11, CORVET/HOPS core subunit" K20179|1|0.0|1857|mmu:71732|vacuolar protein sorting-associated protein 11 "GO:0005768//endosome;GO:0000323//lytic vacuole;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005774//vacuolar membrane;GO:0015629//actin cytoskeleton" GO:0046914//transition metal ion binding GO:0015031//protein transport gi|58037259|ref|NP_082165.1|/0/vacuolar protein sorting-associated protein 11 homolog [Mus musculus] 320181 4864 0.023333333 0.016666667 -0.485426827 Down 0.097493324 Fndc7 fibronectin type III domain containing 7 "K06252|1|2e-11|75.1|spu:576745|tenascin;K18034|3|4e-11|73.9|xtr:101733801|receptor-type tyrosine-protein phosphatase H [EC:3.1.3.48];K16628|4|2e-09|68.2|chx:102188543|collagen, type VII, alpha" - - - gi|260166644|ref|NP_001159437.1|/0/fibronectin type III domain-containing protein 7 isoform 2 precursor [Mus musculus] 271711 2815 0.023333333 0.033333333 0.514573173 Up 0.097493324 Tmem169 transmembrane protein 169 - GO:0031224//intrinsic component of membrane - - gi|30425360|ref|NP_780773.1|/7.69171e-143/transmembrane protein 169 [Mus musculus] 12032 2685 0.026666667 0.036666667 0.459431619 Up 0.097493324 Bcan brevican K06795|1|0.0|1671|mmu:12032|brevican GO:0044421;GO:0043005//neuron projection;GO:0031012//extracellular matrix;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0043005//neuron projection;GO:0031012//extracellular matrix;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding GO:0022610;GO:0021543//pallium development;GO:0048167//regulation of synaptic plasticity;GO:0022610;GO:0021543//pallium development;GO:0048167//regulation of synaptic plasticity gi|157951688|ref|NP_031555.2|/0/brevican core protein isoform 1 precursor [Mus musculus] 13164 2913 0.036666667 0.05 0.447458977 Up 0.097493324 Dazl deleted in azoospermia-like K13126|1|2e-07|61.2|rno:291615|polyadenylate-binding protein;K14411|2|5e-07|59.7|cqu:CpipJ_CPIJ015262|RNA-binding protein Musashi GO:0030529//intracellular ribonucleoprotein complex "GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0036094//small molecule binding;GO:0090079//translation regulator activity, nucleic acid binding" GO:0006413//translational initiation;GO:0048869//cellular developmental process;GO:0007126//meiotic nuclear division;GO:0007292//female gamete generation;GO:0048232//male gamete generation;GO:0003006//developmental process involved in reproduction gi|188497665|ref|NP_034151.3|/7.89613e-146/deleted in azoospermia-like isoform 1 [Mus musculus] 319776 3335 0.023333333 0.033333333 0.514573173 Up 0.097493324 Tmem72 transmembrane protein 72 - GO:0031224//intrinsic component of membrane - - gi|26340664|dbj|BAC33994.1|/1.44906e-127/unnamed protein product [Mus musculus] 19649 4726 0.016666667 0.023333333 0.485426827 Up 0.097493324 Robo3 roundabout guidance receptor 3 "K06755|1|0.0|2327|mmu:19649|roundabout, axon guidance receptor 3" - - - gi|258645167|ref|NP_001158239.1|/0/roundabout homolog 3 [Mus musculus] 56379 3073 0.033333333 0.023333333 -0.514573173 Down 0.097493324 Kcnj1 "potassium inwardly-rectifying channel, subfamily J, member 1" K04995|1|0.0|744|cge:100766584|potassium inwardly-rectifying channel subfamily J member 1 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0032550;GO:0031420;GO:0005242//inward rectifier potassium channel activity;GO:0033218//amide binding;GO:0032550;GO:0031420;GO:0005242//inward rectifier potassium channel activity;GO:0033218//amide binding GO:0048731//system development;GO:1901979//regulation of inward rectifier potassium channel activity;GO:0003096//renal sodium ion transport;GO:0044767//single-organism developmental process;GO:0048871//multicellular organismal homeostasis;GO:0048731//system development;GO:1901979//regulation of inward rectifier potassium channel activity;GO:0003096//renal sodium ion transport;GO:0044767//single-organism developmental process;GO:0048871//multicellular organismal homeostasis gi|270265896|ref|NP_001161826.1|/0/ATP-sensitive inward rectifier potassium channel 1 isoform 1 [Mus musculus] 239766 3120 0.023333333 0.033333333 0.514573173 Up 0.097493324 Rtp1 receptor transporter protein 1 - GO:0044464;GO:0031224//intrinsic component of membrane GO:0001664//G-protein coupled receptor binding - gi|537188965|gb|ERE76764.1|/6.36785e-162/receptor-transporting protein 1 [Cricetulus griseus] 116838 7278 0.02 0.026666667 0.415037499 Up 0.097493324 Rims2 regulating synaptic membrane exocytosis 2 K15297|1|1e-131|474|pale:102888591|regulating synaptic membrane exocytosis protein 2 GO:0032991//macromolecular complex;GO:0042995//cell projection;GO:0032991//macromolecular complex;GO:0042995//cell projection;GO:0032991//macromolecular complex;GO:0042995//cell projection;GO:0032991//macromolecular complex;GO:0097060//synaptic membrane GO:0043169//cation binding;GO:0017016//Ras GTPase binding;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0017016//Ras GTPase binding;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0017016//Ras GTPase binding;GO:0046983//protein dimerization activity;GO:0043169//cation binding;GO:0017016//Ras GTPase binding;GO:0046983//protein dimerization activity GO:0016079//synaptic vesicle exocytosis;GO:0006873//cellular ion homeostasis;GO:0030072//peptide hormone secretion;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0015031//protein transport;GO:0016079//synaptic vesicle exocytosis;GO:0006873//cellular ion homeostasis;GO:0030072//peptide hormone secretion;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0015031//protein transport;GO:0016079//synaptic vesicle exocytosis;GO:0006873//cellular ion homeostasis;GO:0030072//peptide hormone secretion;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0015031//protein transport;GO:0016079//synaptic vesicle exocytosis;GO:0006873//cellular ion homeostasis;GO:0030072//peptide hormone secretion;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0015031//protein transport "gi|148676834|gb|EDL08781.1|/0/regulating synaptic membrane exocytosis 2, isoform CRA_b, partial [Mus musculus]" 12789 3099 0.023333333 0.033333333 0.514573173 Up 0.097493324 Cnga2 cyclic nucleotide gated channel alpha 2 K04949|1|0.0|1205|mmu:12789|cyclic nucleotide gated channel alpha 2 GO:0043025//neuronal cell body;GO:0034703//cation channel complex GO:0030551//cyclic nucleotide binding;GO:0005221//intracellular cyclic nucleotide activated cation channel activity;GO:0005267//potassium channel activity GO:0007606//sensory perception of chemical stimulus;GO:0051260//protein homooligomerization;GO:0051262//protein tetramerization;GO:0042391//regulation of membrane potential;GO:0030001//metal ion transport gi|31982859|ref|NP_031750.2|/0/cyclic nucleotide-gated olfactory channel [Mus musculus] 216377 2357 0.03 0.043333333 0.530514717 Up 0.097493324 Gm38403 "predicted gene, 38403" - - - - - 208869 9067 0.016666667 0.023333333 0.485426827 Up 0.097493324 Dock3 dedicator of cyto-kinesis 3 K05727|1|0.0|3802|mmu:208869|dedicator of cytokinesis protein 3 GO:0044424 GO:0019904//protein domain specific binding GO:0035556//intracellular signal transduction gi|148277096|ref|NP_700462.2|/0/dedicator of cytokinesis protein 3 [Mus musculus] 102871 3738 0.02 0.026666667 0.415037499 Up 0.097493324 D330045A20Rik RIKEN cDNA D330045A20 gene - - - - gi|30425010|ref|NP_780535.1|/0/uncharacterized protein CXorf57 homolog [Mus musculus] 18526 4241 0.023333333 0.016666667 -0.485426827 Down 0.097493324 Pcdh10 protocadherin 10 K16499|1|0.0|1617|mmu:18526|protocadherin delta 2 GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane - GO:0016337//single organismal cell-cell adhesion;GO:0016337//single organismal cell-cell adhesion;GO:0016337//single organismal cell-cell adhesion;GO:0016337//single organismal cell-cell adhesion gi|28972738|dbj|BAC65785.1|/0/mKIAA1400 protein [Mus musculus] 268816 2242 0.03 0.043333333 0.530514717 Up 0.097493324 Mroh5 maestro heat-like repeat family member 5 - - - - gi|85701862|ref|NP_001028537.1|/0/maestro heat-like repeat family member 5 [Mus musculus] 442834 8311 0.026666667 0.02 -0.415037499 Down 0.097493324 D830031N03Rik RIKEN cDNA D830031N03 gene K19827|1|0.0|1444|cge:100770726|microtuble-actin crosslinking factor 1 - - - - 80892 13874 0.026666667 0.02 -0.415037499 Down 0.097493324 Zfhx4 zinc finger homeodomain 4 K09380|1|0.0|6201|mmu:80892|zinc finger homeobox protein 4 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated" gi|125656178|ref|NP_109633.2|/0/zinc finger homeobox protein 4 [Mus musculus] 56072 2755 0.033333333 0.023333333 -0.514573173 Down 0.097493324 Lgals12 "lectin, galactose binding, soluble 12" K10095|1|0.0|654|mmu:56072|galectin-12 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0012501//programmed cell death gi|26351723|dbj|BAC39498.1|/0/unnamed protein product [Mus musculus] 546118 2639 0.023333333 0.033333333 0.514573173 Up 0.097493324 Ubtfl1 "upstream binding transcription factor, RNA polymerase I-like 1" K09273|1|2e-50|203|bacu:103003014|upstream-binding transcription factor - - - - 12769 4324 0.05 0.036666667 -0.447458977 Down 0.097493324 Ccr9 chemokine (C-C motif) receptor 9 K04184|1|0.0|712|mmu:12769|C-C chemokine receptor type 9 GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0004950//chemokine receptor activity;GO:0005488//binding;GO:0004950//chemokine receptor activity;GO:0005488//binding GO:0006952//defense response;GO:0019221//cytokine-mediated signaling pathway;GO:0002376//immune system process;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0006952//defense response;GO:0019221//cytokine-mediated signaling pathway;GO:0002376//immune system process;GO:0051480//regulation of cytosolic calcium ion concentration gi|6753462|ref|NP_034043.1|/0/C-C chemokine receptor type 9 [Mus musculus] 17831 7368 0.016666667 0.023333333 0.485426827 Up 0.097493324 Muc2 mucin 2 K10955|1|0.0|2633|mmu:17831|intestinal mucin-2 - - - gi|410442543|ref|NP_076055.3|/0/mucin-2 precursor [Mus musculus] 433171 2712 0.026666667 0.036666667 0.459431619 Up 0.097493324 Gm10549 predicted gene 10549 - - - - - 214704 3651 0.03 0.04 0.415037499 Up 0.097493324 Iqub IQ motif and ubiquitin domain containing - GO:0005929//cilium;GO:0030141//secretory granule GO:0005488//binding GO:0048858//cell projection morphogenesis gi|255683447|ref|NP_766123.2|/0/IQ and ubiquitin-like domain-containing protein [Mus musculus] 56013 6965 0.033333333 0.046666667 0.485426827 Up 0.097493324 Srcin1 SRC kinase signaling inhibitor 1 K19930|1|0.0|2003|mmu:56013|SRC kinase signaling inhibitor 1 - - - gi|116089329|ref|NP_061361.2|/0/SRC kinase signaling inhibitor 1 [Mus musculus] 433022 7352 0.016666667 0.023333333 0.485426827 Up 0.097493324 Plcxd2 "phosphatidylinositol-specific phospholipase C, X domain containing 2" - - - - gi|197333710|ref|NP_001127952.1|/0/PI-PLC X domain-containing protein 2 [Mus musculus] 241639 5255 0.036666667 0.05 0.447458977 Up 0.097493324 Fermt1 fermitin family member 1 K17082|1|0.0|1268|mmu:241639|kindlin 1 - - - - 18530 3712 0.02 0.026666667 0.415037499 Up 0.097493324 Pcdh8 protocadherin 8 K16499|1|0.0|1648|rno:64865|protocadherin delta 2 GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0097060//synaptic membrane;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0097060//synaptic membrane GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion;GO:0007613//memory;GO:0007267//cell-cell signaling;GO:0009952//anterior/posterior pattern specification;GO:0002009//morphogenesis of an epithelium;GO:0016337//single organismal cell-cell adhesion;GO:0007613//memory;GO:0007267//cell-cell signaling;GO:0009952//anterior/posterior pattern specification;GO:0002009//morphogenesis of an epithelium gi|112181162|ref|NP_067518.2|/0/protocadherin-8 isoform 1 precursor [Mus musculus] 320127 4598 0.043333333 0.03 -0.530514717 Down 0.097493324 Dgki "diacylglycerol kinase, iota" K00901|1|0.0|1924|mmu:320127|diacylglycerol kinase (ATP) [EC:2.7.1.107] - - - gi|124487071|ref|NP_001074675.1|/0/diacylglycerol kinase iota [Mus musculus] 239167 3001 0.023333333 0.033333333 0.514573173 Up 0.097493324 Synb syncytin b "K04257|1|5e-17|92.8|tup:102483054|olfactory receptor;K14684|2|3e-13|80.5|ngi:103726559|solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41;K10279|3|1e-12|78.2|fpg:101911127|F-box and leucine-rich repeat protein 13" GO:0036338 - - "gi|148703999|gb|EDL35946.1|/0/RIKEN cDNA D930020E02, partial [Mus musculus]" 69457 3067 0.05 0.036666667 -0.447458977 Down 0.097493324 Tmem45a2 transmembrane protein 45A2 - - - - - 100270744 3520 0.02 0.026666667 0.415037499 Up 0.097493324 Btbd18 BTB (POZ) domain containing 18 K10443|1|4e-11|73.6|crg:105338741|kelch-like protein 2/3;K10516|3|2e-10|71.2|bacu:103004388|zinc finger and BTB domain-containing protein 45 - - - gi|223029434|ref|NP_001138572.1|/0/BTB/POZ domain-containing protein 18 [Mus musculus] 226781 5836 0.023333333 0.016666667 -0.485426827 Down 0.097493324 Slc30a10 "solute carrier family 30, member 10" "K14697|1|0.0|823|mmu:226781|solute carrier family 30 (zinc transporter), member 10" GO:0031224//intrinsic component of membrane GO:0015075//ion transmembrane transporter activity GO:0000041//transition metal ion transport;GO:0044763 gi|84794621|ref|NP_001028458.1|/0/zinc transporter 10 [Mus musculus] 497097 3652 0.03 0.043333333 0.530514717 Up 0.097493324 Xkr4 X-linked Kx blood group related 4 K01128|1|6e-29|132|clv:102091645|sphingomyelin phosphodiesterase acid-like 3 [EC:3.1.4.-];K19522|2|2e-14|84.3|cge:100762544|membrane transport protein XK - - - - 210673 3710 0.03 0.04 0.415037499 Up 0.097493324 Prrt3 proline-rich transmembrane protein 3 - - - - gi|576067852|ref|NP_001276629.1|/0/proline-rich transmembrane protein 3 isoform a precursor [Mus musculus] 231201 2881 0.05 0.036666667 -0.447458977 Down 0.097493324 AF366264 cDNA sequence AF366264 K03345|1|0.0|1032|mmu:231201|sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68] - GO:0008233//peptidase activity GO:0006915//apoptotic process;GO:0019538//protein metabolic process gi|159032049|ref|NP_694733.3|/0/SUMO-1 specific protease 4 [Mus musculus] 53978 5701 0.036666667 0.026666667 -0.459431619 Down 0.097493324 Lpar2 lysophosphatidic acid receptor 2 K04291|1|8e-164|581|mmu:53978|lysophosphatidic acid receptor 2 "GO:0031224//intrinsic component of membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0045125//bioactive lipid receptor activity;GO:0019904//protein domain specific binding GO:0006468//protein phosphorylation;GO:0007166//cell surface receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0000165//MAPK cascade gi|40254539|ref|NP_064412.2|/6.56914e-163/lysophosphatidic acid receptor 2 [Mus musculus] 381284 7429 0.023333333 0.033333333 0.514573173 Up 0.097493324 Crocc2 "ciliary rootlet coiled-coil, rootletin family member 2" K16469|1|0.0|833|shr:100925514|rootletin - - - "gi|880806933|ref|NP_001297357.1|/0/ciliary rootlet coiled-coil, rootletin family member 2 [Mus musculus]" 78088 3900 0.03 0.04 0.415037499 Up 0.097493324 Sowahb sosondowah ankyrin repeat domain family member B - - - - - 320558 5688 0.016666667 0.023333333 0.485426827 Up 0.097493324 Sycp2 synaptonemal complex protein 2 K19529|1|0.0|2794|mmu:320558|synaptonemal complex protein 2 GO:0000795//synaptonemal complex GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity GO:0012501//programmed cell death;GO:0019953//sexual reproduction;GO:0007129//synapsis;GO:0030539//male genitalia development;GO:0009653//anatomical structure morphogenesis gi|109689713|ref|NP_796165.2|/0/synaptonemal complex protein 2 [Mus musculus] 26909 5506 0.033333333 0.023333333 -0.514573173 Down 0.097493324 Exo1 exonuclease 1 K10746|1|0.0|1661|mmu:26909|exonuclease 1 [EC:3.1.-.-] GO:0043231//intracellular membrane-bounded organelle GO:0008409//5'-3' exonuclease activity;GO:0043169//cation binding;GO:0004520//endodeoxyribonuclease activity;GO:0003677//DNA binding;GO:0008309//double-stranded DNA exodeoxyribonuclease activity;GO:0008297//single-stranded DNA exodeoxyribonuclease activity GO:0006281//DNA repair;GO:0002566//somatic diversification of immune receptors via somatic mutation;GO:0002204//somatic recombination of immunoglobulin genes involved in immune response;GO:0022403 gi|31560511|ref|NP_036142.2|/0/exonuclease 1 [Mus musculus] 74362 7862 0.016666667 0.023333333 0.485426827 Up 0.097493324 Spag17 sperm associated antigen 17 - GO:0015630//microtubule cytoskeleton;GO:0031514//motile cilium - - gi|162287182|ref|NP_083168.3|/0/sperm-associated antigen 17 [Mus musculus] 52504 4343 1.1 1.066666667 -0.044394119 Down 0.097314679 Cenpo centromere protein O K11507|1|7e-170|601|mmu:52504|centromere protein O "GO:0000775//chromosome, centromeric region;GO:0043231//intracellular membrane-bounded organelle" - GO:0044763 gi|29336049|ref|NP_598807.2|/5.97179e-169/centromere protein O [Mus musculus] 67263 5473 1.08 1.113333333 0.04385429 Up 0.097314679 Zswim6 zinc finger SWIM-type containing 6 - - GO:0046914//transition metal ion binding GO:0031175//neuron projection development;GO:0001764//neuron migration gi|210147530|ref|NP_663431.2|/0/zinc finger SWIM domain-containing protein 6 [Mus musculus] 16597 5742 1.023333333 0.993333333 -0.042926325 Down 0.097314679 Klf12 Kruppel-like factor 12 K09205|1|0.0|644|mmu:16597|krueppel-like factor 8/12 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006366//transcription from RNA polymerase II promoter gi|46048263|ref|NP_034766.2|/0/Krueppel-like factor 12 [Mus musculus] 245670 2308 1.09 1.06 -0.04026387 Down 0.097314679 Rragb Ras-related GTP binding B K16185|1|0.0|722|rno:117043|Ras-related GTP-binding protein A/B - - - - 233335 6047.8 1.006666667 1.033333333 0.037719666 Up 0.097314679 Synm "synemin, intermediate filament protein" K10376|1|0.0|2002|mmu:233335|desmuslin GO:0043234//protein complex;GO:0045111//intermediate filament cytoskeleton;GO:0030016//myofibril;GO:0070161;GO:0043234//protein complex;GO:0045111//intermediate filament cytoskeleton;GO:0030016//myofibril;GO:0070161;GO:0043234//protein complex;GO:0045111//intermediate filament cytoskeleton;GO:0030016//myofibril;GO:0070161 GO:0008092//cytoskeletal protein binding;GO:0032403//protein complex binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0032403//protein complex binding;GO:0005198//structural molecule activity;GO:0008092//cytoskeletal protein binding;GO:0032403//protein complex binding;GO:0005198//structural molecule activity - gi|153791809|ref|NP_964001.2|/0/synemin isoform H [Mus musculus] 12774 2926 1.293333333 1.26 -0.037670418 Down 0.097314679 Ccr5 chemokine (C-C motif) receptor 5 K04180|1|0.0|682|mmu:12774|C-C chemokine receptor type 5 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0019957//C-C chemokine binding;GO:0019900//kinase binding;GO:0008092//cytoskeletal protein binding;GO:0004950//chemokine receptor activity GO:0010467//gene expression;GO:0001660//fever generation;GO:0007420//brain development;GO:0019932//second-messenger-mediated signaling;GO:0016337//single organismal cell-cell adhesion;GO:0009314//response to radiation;GO:0019221//cytokine-mediated signaling pathway;GO:0016477//cell migration;GO:0030182//neuron differentiation;GO:0036314;GO:0002376//immune system process;GO:0032731//positive regulation of interleukin-1 beta production;GO:0008285//negative regulation of cell proliferation;GO:0051209//release of sequestered calcium ion into cytosol;GO:0030308//negative regulation of cell growth;GO:0006171//cAMP biosynthetic process;GO:0032496//response to lipopolysaccharide;GO:2000107//negative regulation of leukocyte apoptotic process gi|31542356|ref|NP_034047.2|/0/C-C chemokine receptor type 5 [Mus musculus] 17082 5308 1.17 1.2 0.036525876 Up 0.097314679 Il1rl1 interleukin 1 receptor-like 1 K05171|1|0.0|684|mmu:17082|interleukin 1 receptor-like 1 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0044421;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0044421 GO:0004896//cytokine receptor activity;GO:0004896//cytokine receptor activity;GO:0019955//cytokine binding;GO:0004896//cytokine receptor activity GO:0032722//positive regulation of chemokine production;GO:0001818//negative regulation of cytokine production;GO:0008283//cell proliferation;GO:0002696//positive regulation of leukocyte activation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002823;GO:0006954//inflammatory response;GO:0032722//positive regulation of chemokine production;GO:0001818//negative regulation of cytokine production;GO:0008283//cell proliferation;GO:0002696//positive regulation of leukocyte activation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002823;GO:0006954//inflammatory response;GO:0032722//positive regulation of chemokine production;GO:0001818//negative regulation of cytokine production;GO:0008283//cell proliferation;GO:0002696//positive regulation of leukocyte activation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0002823;GO:0006954//inflammatory response gi|190847349|ref|NP_034873.2|/0/interleukin-1 receptor-like 1 isoform b precursor [Mus musculus] 14265 4426 1.24 1.273333333 0.038270017 Up 0.097314679 Fmr1 fragile X mental retardation syndrome 1 K15516|1|0.0|1126|nle:100606926|fragile X mental retardation protein GO:0043231//intracellular membrane-bounded organelle;GO:0030425//dendrite;GO:0035770//ribonucleoprotein granule;GO:0034518//RNA cap binding complex;GO:0005840//ribosome;GO:0030425//dendrite;GO:0031981//nuclear lumen;GO:0035770//ribonucleoprotein granule;GO:0034518//RNA cap binding complex GO:0005488//binding;GO:0003723//RNA binding GO:0006413//translational initiation;GO:0050658//RNA transport;GO:0007399//nervous system development;GO:0006413//translational initiation;GO:0050658//RNA transport;GO:0007399//nervous system development gi|594150368|ref|NP_001277353.1|/0/fragile X mental retardation protein 1 homolog isoform 2 [Mus musculus] 233064 4744 1.033333333 1.003333333 -0.042504729 Down 0.097314679 Wdr62 WD repeat domain 62 K17917|1|2e-46|191|pxy:105395501|sorting nexin-1/2;K18598|2|1e-21|108|hmg:100207255|echinoderm microtubule-associated protein-like 6 - - - gi|254911023|ref|NP_666298.3|/0/WD repeat-containing protein 62 [Mus musculus] 12442 1541 0.993333333 0.963333333 -0.044242838 Down 0.097314679 Ccnb2 cyclin B2 K05868|1|0.0|773|mmu:12442|cyclin B GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0019900//kinase binding GO:0048534//hematopoietic or lymphoid organ development;GO:0002260//lymphocyte homeostasis;GO:0051726//regulation of cell cycle;GO:0044772//mitotic cell cycle phase transition;GO:0043009//chordate embryonic development;GO:0000087//mitotic M phase gi|86198318|ref|NP_031656.2|/0/G2/mitotic-specific cyclin-B2 [Mus musculus] 100038608 3468 1.096666667 1.126666667 0.038935663 Up 0.097314679 Gm10389 predicted gene 10389 K09228|1|2e-07|61.6|rno:102551340|KRAB domain-containing zinc finger protein;K10591|2|6e-07|59.7|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] - - - - 104348 4032 0.906666667 0.88 -0.043068722 Down 0.097314679 Zfp120 zinc finger protein 120 K09228|1|4e-176|622|cge:100763889|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0005622//intracellular GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|564343476|ref|XP_006235251.1|/0/PREDICTED: zinc finger protein 120 isoform X2 [Rattus norvegicus] 26422 10998 1.003333333 0.976666667 -0.038862822 Down 0.097314679 Nbea neurobeachin K18953|1|3e-95|354|nve:NEMVE_v1g161851|factor associated with neutral sphingomyelinase activation - - - - 12572 7612 3.13 3.076666667 -0.02479451 Down 0.09723946 Cdk7 cyclin-dependent kinase 7 K02202|1|0.0|702|mmu:12572|cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] - - - gi|160333726|ref|NP_034004.2|/0/cyclin-dependent kinase 7 [Mus musculus] 72144 4065 3.846666667 3.793333333 -0.020142666 Down 0.09723946 Slc37a3 "solute carrier family 37 (glycerol-3-phosphate transporter), member 3" "K03447|1|0.0|974|mmu:72144|MFS transporter, OPA family, solute carrier family 37 (glycerol-3-phosphate transporter), member 3" GO:0031224//intrinsic component of membrane - GO:0044765//single-organism transport;GO:0044763 "gi|148681666|gb|EDL13613.1|/0/solute carrier family 37 (glycerol-3-phosphate transporter), member 3, isoform CRA_b, partial [Mus musculus]" 16907 3389 3.173333333 3.126666667 -0.021373651 Down 0.09723946 Lmnb2 lamin B2 K07611|1|0.0|912|mmu:16907|lamin B GO:0031967;GO:0012505//endomembrane system;GO:0005882//intermediate filament;GO:0016020//membrane;GO:0034399//nuclear periphery - - gi|27503473|gb|AAH42430.1|/0/Lamin B2 [Mus musculus] 244349 9126 3.15 3.1 -0.023083613 Down 0.09723946 Kat6a K(lysine) acetyltransferase 6A K11305|1|0.0|3234|mmu:244349|histone acetyltransferase MYST3 [EC:2.3.1.48] GO:0016604//nuclear body;GO:0070775 GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0008080//N-acetyltransferase activity "GO:0030097//hemopoiesis;GO:0006351//transcription, DNA-templated;GO:0034728//nucleosome organization;GO:0007569//cell aging;GO:0035904//aorta development;GO:0019827//stem cell population maintenance;GO:0044092//negative regulation of molecular function;GO:0009887//organ morphogenesis;GO:0016573//histone acetylation" gi|124487239|ref|NP_001074618.1|/0/histone acetyltransferase KAT6A [Mus musculus] 68046 1032 4.723333333 4.776666667 0.016198851 Up 0.09723946 2700062C07Rik RIKEN cDNA 2700062C07 gene - - - - gi|13386028|ref|NP_080805.1|/1.92332e-101/UPF0711 protein C18orf21 homolog [Mus musculus] 80877 9900 3.793333333 3.846666667 0.020142666 Up 0.09723946 Lrba LPS-responsive beige-like anchor K18953|1|1e-87|328|bfo:BRAFLDRAFT_100614|factor associated with neutral sphingomyelinase activation GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane - GO:0044765//single-organism transport;GO:0007154//cell communication;GO:0044765//single-organism transport;GO:0007154//cell communication;GO:0044765//single-organism transport;GO:0007154//cell communication gi|117956399|ref|NP_109620.2|/0/lipopolysaccharide-responsive and beige-like anchor protein isoform alpha [Mus musculus] 14933 4382.87 4.25 4.303333333 0.017991754 Up 0.09723946 Gk glycerol kinase K00864|1|0.0|1092|mmu:14933|glycerol kinase [EC:2.7.1.30] GO:0031966//mitochondrial membrane;GO:0031966//mitochondrial membrane GO:0032550;GO:0005515//protein binding;GO:0016301//kinase activity;GO:0032550;GO:0005515//protein binding;GO:0016301//kinase activity GO:0097305//response to alcohol;GO:0006071//glycerol metabolic process;GO:0006072//glycerol-3-phosphate metabolic process;GO:0006639//acylglycerol metabolic process;GO:0006950//response to stress;GO:0097305//response to alcohol;GO:0006072//glycerol-3-phosphate metabolic process;GO:0019400;GO:0006639//acylglycerol metabolic process gi|659066186|ref|NP_001281067.1|/0/glycerol kinase isoform 3 [Mus musculus] 114741 4491 4.3 4.246666667 -0.018005788 Down 0.09723946 Supt16 suppressor of Ty 16 K04494|1|0.0|1640|aam:106498857|chromodomain helicase DNA binding protein 8 [EC:3.6.4.12];K06100|4|3e-15|87.8|gfr:102044438|symplekin GO:0043232 - "GO:0006259//DNA metabolic process;GO:0006351//transcription, DNA-templated;GO:0033554//cellular response to stress" gi|926702009|ref|XP_005685420.2|/0/PREDICTED: FACT complex subunit SPT16 [Capra hircus] 11990 8740 3.303333333 3.353333333 0.021673343 Up 0.09723946 Atrn attractin "K10895|1|2e-53|215|aqu:100636243|fanconi anemia group I protein;K05636|3|1e-16|93.2|mze:101481347|laminin, beta 1;K06243|5|3e-15|88.6|cjo:107319878|laminin, beta 2" GO:0016021//integral component of membrane;GO:0044424;GO:0044421 GO:0005488//binding GO:0022037//metencephalon development;GO:0006952//defense response;GO:0008366//axon ensheathment;GO:0035264//multicellular organism growth gi|87299635|ref|NP_033860.2|/0/attractin precursor [Mus musculus] 109079 5329 3.296666667 3.246666667 -0.022048749 Down 0.09723946 Sephs1 selenophosphate synthetase 1 "K01008|1|0.0|792|mmu:109079|selenide, water dikinase [EC:2.7.9.3]" - GO:0016301//kinase activity;GO:0032550 GO:0036211//protein modification process;GO:0006796//phosphate-containing compound metabolic process "gi|148676002|gb|EDL07949.1|/0/selenophosphate synthetase 1, isoform CRA_b, partial [Mus musculus]" 244666 2116 4.19 4.14 -0.017319476 Down 0.09723946 Sprtn SprT-like N-terminal domain K08049|1|1e-62|243|dse:Dsec_GM19503|adenylate cyclase 9 [EC:4.6.1.1] GO:0043232 GO:0031593//polyubiquitin binding;GO:0043169//cation binding GO:0006301//postreplication repair;GO:0009416//response to light stimulus;GO:0016567//protein ubiquitination gi|162138940|ref|NP_001104611.1|/0/sprT-like domain-containing protein Spartan [Mus musculus] 233315 5205 3.436666667 3.486666667 0.020838519 Up 0.09723946 Mtmr10 myotubularin related protein 10 K18085|1|0.0|1498|mmu:233315|myotubularin-related protein 10/11/12 - GO:0042578//phosphoric ester hydrolase activity GO:0006796//phosphate-containing compound metabolic process gi|124028523|ref|NP_766330.2|/0/myotubularin-related protein 10 [Mus musculus] 70354 6797 3.056666667 3.11 0.024955347 Up 0.09723946 Secisbp2l SECIS binding protein 2-like K19539|1|1e-90|338|fab:101821034|selenocysteine insertion sequence-binding protein 2 - - - gi|50510425|dbj|BAD32198.1|/0/mKIAA0256 protein [Mus musculus] 93689 3942 3.103333333 3.053333333 -0.023433569 Down 0.09723946 Lmod1 leiomodin 1 (smooth muscle) K10370|1|2e-31|140|pbi:103059461|tropomodulin - - - gi|134948541|ref|NP_444336.2|/0/leiomodin-1 [Mus musculus] 29815 3316 2.726666667 2.773333333 0.024482685 Up 0.09723946 Bcar3 breast cancer anti-estrogen resistance 3 K07527|1|3e-12|77.0|cmk:103188558|tyrosine-protein kinase Fes/Fps [EC:2.7.10.2];K08889|2|2e-11|74.3|tru:101074039|tyrosine-protein kinase Fer [EC:2.7.10.2] GO:0044464 GO:0030695//GTPase regulator activity GO:0042221//response to chemical;GO:0035556//intracellular signal transduction gi|7304925|ref|NP_038895.1|/0/breast cancer anti-estrogen resistance protein 3 [Mus musculus] 98403 3860.6 2.82 2.773333333 -0.024074135 Down 0.09723946 Zfp451 zinc finger protein 451 K09228|1|1e-15|89.0|sko:100378647|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|29789329|ref|NP_598578.1|/0/zinc finger protein 451 isoform 1 [Mus musculus] 233812 4842 3.38 3.43 0.02118533 Up 0.09723946 BC030336 cDNA sequence BC030336 K18328|1|5e-49|199|ame:551497|lariat debranching enzyme [EC:3.1.-.-] - - - gi|657801905|ref|XP_008328052.1|/2.52393e-91/PREDICTED: uncharacterized protein C16orf52 homolog [Cynoglossus semilaevis] 55935 4691 5.15 5.096666667 -0.015018431 Down 0.09723946 Fnbp4 formin binding protein 4 - - - - gi|9055220|ref|NP_061298.1|/0/formin-binding protein 4 [Mus musculus] 15446 1719 3.993333333 4.046666667 0.019140513 Up 0.09723946 Hpgd hydroxyprostaglandin dehydrogenase 15 (NAD) K00069|1|3e-150|534|mmu:15446|15-hydroxyprostaglandin dehydrogenase (NAD) [EC:1.1.1.141] GO:0031981//nuclear lumen "GO:0043168//anion binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0004955//prostaglandin receptor activity" GO:0022602//ovulation cycle process;GO:0044703;GO:0048844//artery morphogenesis;GO:0051726//regulation of cell cycle;GO:0006692;GO:0007292//female gamete generation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway gi|124486706|ref|NP_032304.2|/2.2965e-149/15-hydroxyprostaglandin dehydrogenase [NAD(+)] [Mus musculus] 103836 1887 2.993333333 2.943333333 -0.024302007 Down 0.09723946 Zfp692 zinc finger protein 692 K04961|1|3e-54|215|ocu:103351584|ryanodine receptor 1;K09228|2|3e-24|116|obi:106868814|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|100817070|ref|NP_001035776.1|/0/zinc finger protein 692 [Mus musculus] 72175 3051 3.926666667 3.876666667 -0.018488442 Down 0.09723946 Mfsd8 major facilitator superfamily domain containing 8 "K12307|1|0.0|939|mmu:72175|MFS transporter, ceroid-lipofuscinosis neuronal protein 7" GO:0031224//intrinsic component of membrane;GO:0000323//lytic vacuole - GO:0051234//establishment of localization;GO:0044763 gi|31541926|ref|NP_082416.2|/0/major facilitator superfamily domain-containing protein 8 [Mus musculus] 19365 1689.75 4.736666667 4.686666667 -0.01530996 Down 0.09723946 Rad52 "RAD52 homolog, DNA repair protein" K10873|1|0.0|785|mmu:19365|DNA repair and recombination protein RAD52 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress "gi|148667210|gb|EDK99626.1|/0/RAD52 homolog (S. cerevisiae), isoform CRA_f, partial [Mus musculus]" 50527 4435 4.49 4.44 -0.016155768 Down 0.09723946 Ero1l ERO1-like (S. cerevisiae) K10950|1|0.0|924|mmu:50527|ERO1-like protein alpha [EC:1.8.4.-] - - - - 74133 3236 4.543333333 4.49 -0.017035711 Down 0.09723946 Smg8 "smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans)" K18734|1|0.0|1888|mmu:74133|protein SMG8 - - GO:0001932//regulation of protein phosphorylation gi|23956216|ref|NP_077224.1|/0/protein SMG8 [Mus musculus] 140630 6067 4.66 4.606666667 -0.016606745 Down 0.09723946 Ube4a ubiquitination factor E4A K10596|1|0.0|2026|mmu:140630|ubiquitin conjugation factor E4 A [EC:2.3.2.27] GO:0043234//protein complex;GO:0044424 GO:0005488//binding;GO:0004842//ubiquitin-protein transferase activity GO:0019941//modification-dependent protein catabolic process;GO:0016567//protein ubiquitination gi|50510371|dbj|BAD32171.1|/0/mKIAA0126 protein [Mus musculus] 93685 6050 0.413333333 0.39 -0.083831591 Down 0.09720185 Entpd7 ectonucleoside triphosphate diphosphohydrolase 7 K14643|1|0.0|1154|mmu:93685|ectonucleoside triphosphate diphosphohydrolase 7 [EC:3.6.1.-] GO:0031224//intrinsic component of membrane;GO:0012506//vesicle membrane GO:0016462//pyrophosphatase activity GO:0009134//nucleoside diphosphate catabolic process;GO:0009143//nucleoside triphosphate catabolic process gi|82617566|ref|NP_444333.3|/0/ectonucleoside triphosphate diphosphohydrolase 7 [Mus musculus] 13436 4092 0.433333333 0.456666667 0.07566427 Up 0.09720185 Dnmt3b DNA methyltransferase 3B K17399|1|0.0|1361|mmu:13436|DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37] GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin GO:0003712//transcription cofactor activity;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0043169//cation binding;GO:0003712//transcription cofactor activity;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0043169//cation binding;GO:0003712//transcription cofactor activity;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0043169//cation binding;GO:0003712//transcription cofactor activity;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0043169//cation binding;GO:0003712//transcription cofactor activity;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0043169//cation binding;GO:0003712//transcription cofactor activity;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0043169//cation binding;GO:0003712//transcription cofactor activity;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0043169//cation binding;GO:0003712//transcription cofactor activity;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0043169//cation binding;GO:0003712//transcription cofactor activity;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0043169//cation binding GO:0006366//transcription from RNA polymerase II promoter;GO:0031062//positive regulation of histone methylation;GO:0006342//chromatin silencing;GO:0032776//DNA methylation on cytosine;GO:0008104//protein localization;GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0009314//response to radiation;GO:0031061//negative regulation of histone methylation;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031062//positive regulation of histone methylation;GO:0006342//chromatin silencing;GO:0032776//DNA methylation on cytosine;GO:0008104//protein localization;GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0009314//response to radiation;GO:0031061//negative regulation of histone methylation;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031062//positive regulation of histone methylation;GO:0006342//chromatin silencing;GO:0032776//DNA methylation on cytosine;GO:0008104//protein localization;GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0031061//negative regulation of histone methylation;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031062//positive regulation of histone methylation;GO:0006342//chromatin silencing;GO:0032776//DNA methylation on cytosine;GO:0008104//protein localization;GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0031061//negative regulation of histone methylation;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031062//positive regulation of histone methylation;GO:0006342//chromatin silencing;GO:0032776//DNA methylation on cytosine;GO:0008104//protein localization;GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0009314//response to radiation;GO:0031061//negative regulation of histone methylation;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031062//positive regulation of histone methylation;GO:0006342//chromatin silencing;GO:0032776//DNA methylation on cytosine;GO:0008104//protein localization;GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0009314//response to radiation;GO:0031061//negative regulation of histone methylation;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031062//positive regulation of histone methylation;GO:0006342//chromatin silencing;GO:0032776//DNA methylation on cytosine;GO:0008104//protein localization;GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0009314//response to radiation;GO:0031061//negative regulation of histone methylation;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031062//positive regulation of histone methylation;GO:0006342//chromatin silencing;GO:0032776//DNA methylation on cytosine;GO:0008104//protein localization;GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0031061//negative regulation of histone methylation;GO:0030182//neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0031062//positive regulation of histone methylation;GO:0006342//chromatin silencing;GO:0032776//DNA methylation on cytosine;GO:0008104//protein localization;GO:0006790//sulfur compound metabolic process;GO:0043200//response to amino acid;GO:0031061//negative regulation of histone methylation;GO:0030182//neuron differentiation gi|568915295|ref|XP_006498749.1|/0/PREDICTED: DNA (cytosine-5)-methyltransferase 3B isoform X5 [Mus musculus] 216867 1773 0.363333333 0.383333333 0.077305726 Up 0.09720185 Slc16a11 "solute carrier family 16 (monocarboxylic acid transporters), member 11" "K08188|1|1e-118|429|mmu:216867|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 11" - - - gi|197246084|gb|AAI69003.1|/8.2855e-126/Slc16a11 protein [Rattus norvegicus] 12803 1205 0.366666667 0.346666667 -0.080919995 Down 0.09720185 Cntf ciliary neurotrophic factor K05420|1|2e-109|398|mmu:12803|ciliary neurotrophic factor GO:0043005//neuron projection;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0044421 GO:0005126//cytokine receptor binding GO:0001775//cell activation;GO:0045665//negative regulation of neuron differentiation;GO:0031103//axon regeneration;GO:0042391//regulation of membrane potential;GO:0016049//cell growth;GO:0009967//positive regulation of signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0046879//hormone secretion;GO:0008283//cell proliferation;GO:0051259//protein oligomerization;GO:0043066//negative regulation of apoptotic process;GO:0000165//MAPK cascade;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0009887//organ morphogenesis gi|25952141|ref|NP_740756.1|/1.57394e-108/ciliary neurotrophic factor [Mus musculus] 16840 1462 0.37 0.35 -0.080170349 Down 0.09720185 Lect1 leukocyte cell derived chemotaxin 1 - GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464 - GO:0001525//angiogenesis;GO:0001503//ossification;GO:0009968//negative regulation of signal transduction;GO:0001885//endothelial cell development;GO:0001501//skeletal system development;GO:0001935//endothelial cell proliferation;GO:0001525//angiogenesis;GO:0001503//ossification;GO:0009968//negative regulation of signal transduction;GO:0001885//endothelial cell development;GO:0001501//skeletal system development;GO:0001935//endothelial cell proliferation gi|893571730|ref|NP_001297584.1|/0/leukocyte cell-derived chemotaxin 1 isoform 1 [Mus musculus] 21367 9535 0.42 0.443333333 0.078002512 Up 0.09720185 Cntn2 contactin 2 K06760|1|0.0|2023|mmu:21367|contactin 2 GO:0044297//cell body;GO:0033267;GO:0005887//integral component of plasma membrane GO:0005515//protein binding GO:0007010//cytoskeleton organization;GO:0034613//cellular protein localization;GO:0014003//oligodendrocyte development;GO:0007611//learning or memory;GO:0006898//receptor-mediated endocytosis;GO:0001973//adenosine receptor signaling pathway;GO:0007409//axonogenesis;GO:0048167//regulation of synaptic plasticity;GO:0021830//interneuron migration from the subpallium to the cortex;GO:0032536//regulation of cell projection size;GO:0016485//protein processing;GO:0031589//cell-substrate adhesion;GO:0045685//regulation of glial cell differentiation;GO:0045184//establishment of protein localization;GO:0006935//chemotaxis;GO:0045161//neuronal ion channel clustering;GO:0008344//adult locomotory behavior gi|54607084|ref|NP_796103.2|/0/contactin-2 precursor [Mus musculus] 216227 3854 0.356666667 0.376666667 0.078711976 Up 0.09720185 Slc17a8 "solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8" "K12302|1|0.0|1206|mmu:216227|MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8" GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle;GO:0042995//cell projection GO:0015291//secondary active transmembrane transporter activity;GO:0005310//dicarboxylic acid transmembrane transporter activity GO:0044763;GO:0050954//sensory perception of mechanical stimulus;GO:0006835//dicarboxylic acid transport;GO:0030001//metal ion transport;GO:0006865//amino acid transport gi|33695072|ref|NP_892004.1|/0/vesicular glutamate transporter 3 isoform 1 [Mus musculus] 14345 3664 0.293333333 0.31 0.079727192 Up 0.09720185 Fut4 fucosyltransferase 4 "K07632|1|0.0|913|mmu:14345|galactoside alpha-1,3-fucosyltransferase 4 [EC:2.4.1.-]" - - - - 21908 2030 0.296666667 0.313333333 0.078855421 Up 0.09720185 Tlx1 "T cell leukemia, homeobox 1" K09340|1|6e-112|403|cjc:100388140|T-cell leukemia homeobox protein 1 - GO:0046983//protein dimerization activity GO:0048534//hematopoietic or lymphoid organ development;GO:0009887//organ morphogenesis;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter gi|675710970|ref|XP_002756582.2|/5.30397e-111/PREDICTED: T-cell leukemia homeobox protein 1 isoform X2 [Callithrix jacchus] 20416 3211.84 16.45 16.57 0.010486019 Up 0.097164241 Shc1 src homology 2 domain-containing transforming protein C1 K06279|1|0.0|939|mmu:20416|SHC-transforming protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0031090//organelle membrane GO:0005167;GO:0070851//growth factor receptor binding;GO:0045309//protein phosphorylated amino acid binding;GO:0005167;GO:0070851//growth factor receptor binding;GO:0045309//protein phosphorylated amino acid binding GO:0007155//cell adhesion;GO:0040007//growth;GO:0019229//regulation of vasoconstriction;GO:0000302//response to reactive oxygen species;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0043434//response to peptide hormone;GO:0008284//positive regulation of cell proliferation;GO:0030030//cell projection organization;GO:0006468//protein phosphorylation;GO:0009887//organ morphogenesis;GO:0030154//cell differentiation;GO:0031960//response to corticosteroid;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0006260//DNA replication;GO:0007155//cell adhesion;GO:0040007//growth;GO:0019229//regulation of vasoconstriction;GO:0000302//response to reactive oxygen species;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0043434//response to peptide hormone;GO:0008284//positive regulation of cell proliferation;GO:0030030//cell projection organization;GO:0006468//protein phosphorylation;GO:0009887//organ morphogenesis;GO:0030154//cell differentiation;GO:0031960//response to corticosteroid;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0006260//DNA replication gi|164664522|ref|NP_001106802.1|/0/SHC-transforming protein 1 isoform a [Mus musculus] 67390 1492 15.90666667 15.78666667 -0.010924962 Down 0.097164241 Rnmtl1 RNA methyltransferase like 1 K20095|1|0.0|848|mmu:67390|16S rRNA (guanosine(1370)-2'-O)-methyltransferase [EC:2.1.1.-] GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity GO:0010467//gene expression "gi|166197675|ref|NP_899086.2|/0/rRNA methyltransferase 3, mitochondrial [Mus musculus]" 67678 631 29.49666667 29.38 -0.005717533 Down 0.097164241 Lsm3 "LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated" K12622|1|1e-37|157|pale:102895065|U6 snRNA-associated Sm-like protein LSm3 - - - - 227700 1844.33 29.92 30.03666667 0.005614543 Up 0.097164241 Sh3glb2 SH3-domain GRB2-like endophilin B2 K11248|1|1e-160|568|ssc:100156344|endophilin-B GO:0044424;GO:0044424 GO:0005515//protein binding;GO:0005515//protein binding GO:0044763;GO:0044763 gi|755497434|ref|XP_011237379.1|/2.5952e-166/PREDICTED: endophilin-B2 isoform X5 [Mus musculus] 64436 3992.12 25.05333333 25.17 0.00670265 Up 0.097164241 Inpp5e inositol polyphosphate-5-phosphatase E K20278|1|0.0|1244|mmu:64436|inositol polyphosphate 5-phosphatase INPP5E [EC:3.1.3.36] GO:0000139//Golgi membrane;GO:0043232;GO:0005930//axoneme;GO:0000139//Golgi membrane;GO:0043232;GO:0005930//axoneme;GO:0000139//Golgi membrane;GO:0043232;GO:0005930//axoneme GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0046030//inositol trisphosphate phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0046030//inositol trisphosphate phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0046030//inositol trisphosphate phosphatase activity GO:0046488//phosphatidylinositol metabolic process;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0010975//regulation of neuron projection development;GO:0046488//phosphatidylinositol metabolic process;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0010975//regulation of neuron projection development;GO:0046488//phosphatidylinositol metabolic process;GO:0046838//phosphorylated carbohydrate dephosphorylation;GO:0010975//regulation of neuron projection development gi|14916467|ref|NP_149125.1|/0/72 kDa inositol polyphosphate 5-phosphatase isoform a [Mus musculus] 26398 3654.88 15.48333333 15.36 -0.01153788 Down 0.097164241 Map2k4 mitogen-activated protein kinase kinase 4 K04430|1|0.0|752|hgl:101705822|mitogen-activated protein kinase kinase 4 [EC:2.7.12.2] - - - - 192191 3013 13.09 13.21 0.013165369 Up 0.097164241 Med9 mediator complex subunit 9 K15149|1|7e-46|188|mmu:192191|mediator of RNA polymerase II transcription subunit 9 - - - gi|31981674|ref|NP_619616.2|/6.13653e-45/mediator of RNA polymerase II transcription subunit 9 [Mus musculus] 70120 1587 12.71333333 12.83666667 0.013928279 Up 0.097164241 Yars2 tyrosyl-tRNA synthetase 2 (mitochondrial) K01866|1|0.0|594|mmu:70120|tyrosyl-tRNA synthetase [EC:6.1.1.1] GO:0044429;GO:0044429 GO:0032550;GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0016597//amino acid binding;GO:0032550;GO:0003676//nucleic acid binding;GO:0042802//identical protein binding;GO:0004812//aminoacyl-tRNA ligase activity;GO:0016597//amino acid binding GO:0000959//mitochondrial RNA metabolic process;GO:0006418//tRNA aminoacylation for protein translation;GO:0000959//mitochondrial RNA metabolic process;GO:0006418//tRNA aminoacylation for protein translation "gi|148664996|gb|EDK97412.1|/0/tyrosyl-tRNA synthetase 2 (mitochondrial), isoform CRA_a [Mus musculus]" 105246 2447.37 12.69666667 12.81333333 0.013196048 Up 0.097164241 Brd9 bromodomain containing 9 K11723|1|0.0|909|mmu:105246|bromodomain-containing protein 7/9 - GO:0042393//histone binding;GO:0042393//histone binding "GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" gi|564324966|ref|XP_006227849.1|/0/PREDICTED: bromodomain-containing protein 9 isoform X3 [Rattus norvegicus] 22294 833 26.69 26.81 0.006471914 Up 0.097164241 Uxt ubiquitously expressed transcript - GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003779//actin binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0015631//tubulin binding "GO:0031023//microtubule organizing center organization;GO:0044267//cellular protein metabolic process;GO:0034643//establishment of mitochondrion localization, microtubule-mediated;GO:0006366//transcription from RNA polymerase II promoter" gi|8928448|sp|Q9WTZ0.1|UXT_MOUSE/1.32365e-69/RecName: Full=Protein UXT; AltName: Full=Ubiquitously expressed transcript protein 13661 4387 0.033333333 0.026666667 -0.321928095 Down 0.09684456 Ehf ets homologous factor K17102|1|3e-180|635|mmu:13661|ETS homologous factor GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated" "gi|148695743|gb|EDL27690.1|/0/ets homologous factor, isoform CRA_d, partial [Mus musculus]" 100040599 2514 0.043333333 0.033333333 -0.378511623 Down 0.09684456 Gm15319 predicted gene 15319 K17299|1|0.0|643|mmu:100040599|POTE ankyrin domain family protein - - - gi|294345444|ref|NP_001170879.1|/0/testis-specific gene with ankyrin repeats and PEST domain-like [Mus musculus] 74087 2134 0.03 0.023333333 -0.362570079 Down 0.09684456 Slc7a13 "solute carrier family 7, (cationic amino acid transporter, y+ system) member 13" "K13870|1|0.0|949|mmu:74087|solute carrier family 7 (L-type amino acid transporter), member 13" GO:0031224//intrinsic component of membrane GO:0046943//carboxylic acid transmembrane transporter activity GO:0046942//carboxylic acid transport gi|20270204|ref|NP_083022.1|/0/solute carrier family 7 member 13 [Mus musculus] 12891 2021 0.033333333 0.026666667 -0.321928095 Down 0.09684456 Cpne6 copine VI K11348|1|1e-09|68.2|apla:101800649|bromodomain and PHD finger-containing protein 1 - - - - 329641 3086 0.036666667 0.046666667 0.347923303 Up 0.09684456 Sertm1 serine rich and transmembrane domain containing 1 - - - - "gi|148703340|gb|EDL35287.1|/2.65589e-27/RIKEN cDNA 6030405A18, isoform CRA_a, partial [Mus musculus]" 16591 5124 0.026666667 0.033333333 0.321928095 Up 0.09684456 Kl klotho K14756|1|0.0|1912|mmu:16591|klotho [EC:3.2.1.31] GO:0031224//intrinsic component of membrane "GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0070851//growth factor receptor binding;GO:0019838//growth factor binding" GO:0044238//primary metabolic process;GO:0055065//metal ion homeostasis;GO:0044767//single-organism developmental process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0030282//bone mineralization;GO:0015980//energy derivation by oxidation of organic compounds "gi|148673938|gb|EDL05885.1|/0/klotho, isoform CRA_a, partial [Mus musculus]" 110876 8690 0.023333333 0.03 0.362570079 Up 0.09684456 Scn2a1 "sodium channel, voltage-gated, type II, alpha 1" K04834|1|0.0|3481|mmu:110876|voltage-gated sodium channel type II alpha - - - - 232409 2271 0.046666667 0.06 0.362570079 Up 0.09684456 Clec2e "C-type lectin domain family 2, member e" K10071|1|2e-81|302|mmu:94071|C-type lectin domain family 2 member B;K10072|4|4e-75|285|cge:100761404|C-type lectin domain family 2 member D GO:0016021//integral component of membrane GO:0005102//receptor binding GO:0006952//defense response;GO:0007154//cell communication gi|130488531|ref|NP_705726.3|/7.35218e-117/C-type lectin domain family 2 member E [Mus musculus] 320571 4474 0.023333333 0.03 0.362570079 Up 0.09684456 Atp8b5 "ATPase, class I, type 8B, member 5" K01530|1|0.0|1499|lcm:102350213|phospholipid-translocating ATPase [EC:3.6.3.1] - - - - 100038627 3164 0.023333333 0.03 0.362570079 Up 0.09684456 F630042J09Rik RIKEN cDNA F630042J09 gene - - - - - 21942 1999 0.033333333 0.026666667 -0.321928095 Down 0.09684456 Tnfrsf9 "tumor necrosis factor receptor superfamily, member 9" K05146|1|1e-135|486|mmu:21942|tumor necrosis factor receptor superfamily member 9 GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0044421 GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0050710//negative regulation of cytokine secretion;GO:0051260//protein homooligomerization;GO:0008283//cell proliferation;GO:0050710//negative regulation of cytokine secretion;GO:0051260//protein homooligomerization;GO:0008283//cell proliferation;GO:0050710//negative regulation of cytokine secretion;GO:0051260//protein homooligomerization;GO:0008283//cell proliferation gi|117422435|ref|NP_001070976.1|/4.48089e-123/tumor necrosis factor receptor superfamily member 9 isoform 2 precursor [Mus musculus] 71395 2928 0.05 0.063333333 0.341036918 Up 0.09684456 5430419D17Rik RIKEN cDNA 5430419D17 gene K13912|1|0.0|1680|mmu:71395|deleted in malignant brain tumors 1 protein - - - "gi|148685749|gb|EDL17696.1|/0/RIKEN cDNA 5430419D17, partial [Mus musculus]" 272636 4491 0.03 0.023333333 -0.362570079 Down 0.09684456 Esyt3 extended synaptotagmin-like protein 3 K19513|1|2e-19|101|tsp:Tsp_01622|protein CLEC16A;K17598|2|2e-15|88.2|tru:101063659|synaptotagmin-like protein GO:0031224//intrinsic component of membrane - - gi|60360572|dbj|BAD90311.1|/0/mKIAA4186 protein [Mus musculus] 13075 2373 0.05 0.04 -0.321928095 Down 0.09684456 Cyp19a1 "cytochrome P450, family 19, subfamily a, polypeptide 1" K07434|1|0.0|969|mmu:13075|aromatase [EC:1.14.14.14] GO:0044297//cell body;GO:0030425//dendrite;GO:0033267;GO:0030136//clathrin-coated vesicle "GO:0046914//transition metal ion binding;GO:0046906//tetrapyrrole binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0001501//skeletal system development;GO:0071363//cellular response to growth factor stimulus;GO:0021536//diencephalon development;GO:0008207//C21-steroid hormone metabolic process;GO:0002573//myeloid leukocyte differentiation;GO:0006694//steroid biosynthetic process;GO:0014072//response to isoquinoline alkaloid;GO:0043627//response to estrogen;GO:0008406//gonad development;GO:0042537//benzene-containing compound metabolic process;GO:0021543//pallium development;GO:0010038//response to metal ion;GO:0007268//chemical synaptic transmission;GO:0009314//response to radiation;GO:0033554//cellular response to stress;GO:0035270//endocrine system development;GO:0032870//cellular response to hormone stimulus;GO:0001678//cellular glucose homeostasis;GO:0032354//response to follicle-stimulating hormone gi|6681099|ref|NP_031836.1|/0/aromatase [Mus musculus] 330577 2788 0.026666667 0.033333333 0.321928095 Up 0.09684456 Saxo2 stablizer of axonemal microtubules 2 K08622|1|2e-27|127|mcf:102132317|a disintegrin and metalloproteinase with thrombospondin motifs 7 [EC:3.4.24.-] - - - gi|134288850|ref|NP_808562.3|/0/stabilizer of axonemal microtubules 2 [Mus musculus] 235415 2859 0.03 0.023333333 -0.362570079 Down 0.09684456 Cplx3 complexin 3 K15295|1|2e-67|260|rno:501005|complexin-3/4 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0000149//SNARE binding;GO:0005215//transporter activity GO:0006887//exocytosis;GO:0007269//neurotransmitter secretion;GO:0030072//peptide hormone secretion gi|22122785|ref|NP_666335.1|/1.56009e-66/complexin-3 precursor [Mus musculus] 212391 4663 0.043333333 0.033333333 -0.378511623 Down 0.09684456 Lcor ligand dependent nuclear receptor corepressor "K20015|1|6e-08|63.5|crg:105346628|ecdysone-induced protein 93F, isoform B" - - - gi|37360548|dbj|BAC98252.1|/0/mKIAA1795 protein [Mus musculus] 18430 4568 0.033333333 0.043333333 0.378511623 Up 0.09684456 Oxtr oxytocin receptor K04229|1|0.0|686|mmu:18430|oxytocin receptor GO:0005911//cell-cell junction;GO:0031224//intrinsic component of membrane;GO:0042995//cell projection;GO:0044459 GO:0008528//G-protein coupled peptide receptor activity;GO:0042277//peptide binding "GO:0014075//response to amine;GO:0007166//cell surface receptor signaling pathway;GO:0051705;GO:0007611//learning or memory;GO:0060746//parental behavior;GO:0007320//insemination;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0043084//penile erection;GO:0043627//response to estrogen;GO:0030900//forebrain development;GO:0022602//ovulation cycle process;GO:0001696//gastric acid secretion;GO:0035249//synaptic transmission, glutamatergic;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0045987//positive regulation of smooth muscle contraction;GO:0000165//MAPK cascade;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0007567//parturition;GO:0014061//regulation of norepinephrine secretion;GO:0008217//regulation of blood pressure;GO:0007416//synapse assembly" gi|1902964|dbj|BAA18995.1|/0/oxytocin receptor [Mus sp.] 216453 1889 0.043333333 0.033333333 -0.378511623 Down 0.09684456 Rdh19 retinol dehydrogenase 19 K11154|1|6e-164|580|mmu:19683|retinol dehydrogenase 16 [EC:1.1.1.-] GO:0044432;GO:0016021//integral component of membrane "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0042802//identical protein binding;GO:0036094//small molecule binding" GO:0002138//retinoic acid biosynthetic process gi|117320520|ref|NP_671755.2|/1.67307e-180/retinol dehydrogenase similar protein 2 precursor [Mus musculus] 208628 6961 0.053333333 0.066666667 0.321928095 Up 0.09684456 Kntc1 kinetochore associated 1 K11577|1|0.0|4177|mmu:208628|kinetochore-associated protein 1 - - - gi|50510395|dbj|BAD32183.1|/0/mKIAA0166 protein [Mus musculus] 99686 2164 0.06 0.046666667 -0.362570079 Down 0.09684456 AI606473 expressed sequence AI606473 - - - - - 378776 4233 0.043333333 0.033333333 -0.378511623 Down 0.09684456 Pcsk2os1 "proprotein convertase subtilisin/kexin type 2, opposite strand 1" K01360|1|1e-27|129|mmu:18549|proprotein convertase subtilisin/kexin type 2 [EC:3.4.21.94] - - - - 14402 5516 0.033333333 0.043333333 0.378511623 Up 0.09684456 Gabrb3 "gamma-aminobutyric acid (GABA) A receptor, subunit beta 3" K05181|1|0.0|917|pon:100171629|gamma-aminobutyric acid receptor subunit beta GO:0033267;GO:0097060//synaptic membrane;GO:0034702//ion channel complex GO:0005253//anion channel activity;GO:0032403//protein complex binding;GO:0015276//ligand-gated ion channel activity GO:0050954//sensory perception of mechanical stimulus;GO:0021675//nerve development;GO:0015698//inorganic anion transport;GO:0007270//neuron-neuron synaptic transmission;GO:0048666//neuron development;GO:0007186//G-protein coupled receptor signaling pathway gi|84662774|ref|NP_001033790.1|/0/gamma-aminobutyric acid receptor subunit beta-3 isoform b precursor [Mus musculus] 211612 6489 0.023333333 0.03 0.362570079 Up 0.09684456 Ptchd1 patched domain containing 1 K12385|1|7e-25|120|lgi:LOTGIDRAFT_199271|Niemann-Pick C1 protein;K14461|5|7e-22|110|ola:101160914|Niemann-Pick C1-like protein 1 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0050877//neurological system process;GO:0007166//cell surface receptor signaling pathway gi|148271102|ref|NP_001087219.1|/0/patched domain-containing protein 1 [Mus musculus] 245403 2881 0.06 0.046666667 -0.362570079 Down 0.09684456 Dcaf12l2 DDB1 and CUL4 associated factor 12-like 2 K11803|1|1e-150|536|bacu:103004398|WD repeat-containing protein 40A - - - gi|30425322|ref|NP_780748.1|/0/DDB1- and CUL4-associated factor 12-like protein 2 [Mus musculus] 18039 2014 0.033333333 0.026666667 -0.321928095 Down 0.09684456 Nefl "neurofilament, light polypeptide" K04572|1|0.0|685|mmu:18039|neurofilament light polypeptide GO:0043005//neuron projection;GO:0005882//intermediate filament GO:0005198//structural molecule activity;GO:0019899//enzyme binding GO:0043066//negative regulation of apoptotic process;GO:0032536//regulation of cell projection size;GO:0051384//response to glucocorticoid;GO:0031103//axon regeneration;GO:0045110//intermediate filament bundle assembly;GO:0043623//cellular protein complex assembly;GO:0008088//axo-dendritic transport;GO:0050905//neuromuscular process gi|984126115|ref|XP_015354881.1|/0/PREDICTED: neurofilament light polypeptide [Marmota marmota marmota] 100093700 3835 0.033333333 0.026666667 -0.321928095 Down 0.09684456 Gm10400 predicted gene 10400 - - - - gi|74228624|dbj|BAE25383.1|/8.38006e-26/unnamed protein product [Mus musculus] 68203 4348 0.04 0.05 0.321928095 Up 0.09684456 Diras2 "DIRAS family, GTP-binding RAS-like 2" "K07841|1|1e-97|361|rno:291006|DIRAS family, GTP-binding Ras-like 2" GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process gi|71725385|ref|NP_001019645.1|/1.04173e-96/GTP-binding protein Di-Ras2 [Mus musculus] 667666 4248 0.023333333 0.03 0.362570079 Up 0.09684456 Zfp600 zinc finger protein 600 K09228|1|0.0|1756|mmu:102632968|KRAB domain-containing zinc finger protein - - - - 207742 4336 0.04 0.05 0.321928095 Up 0.09684456 Rnf43 ring finger protein 43 K15694|1|0.0|1460|mmu:207742|RING finger protein 43 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane GO:0046914//transition metal ion binding;GO:0001664//G-protein coupled receptor binding;GO:0003824//catalytic activity GO:0030178//negative regulation of Wnt signaling pathway;GO:0016567//protein ubiquitination;GO:0008283//cell proliferation gi|167830481|ref|NP_766036.2|/0/E3 ubiquitin-protein ligase RNF43 precursor [Mus musculus] 446101 2631 0.046666667 0.036666667 -0.347923303 Down 0.09684456 Xrra1 X-ray radiation resistance associated 1 K18809|1|8e-06|55.5|cfo:105250921|protein toll;K18808|2|8e-06|55.5|xtr:100485706|toll-like receptor 13 GO:0043231//intracellular membrane-bounded organelle - GO:0010212//response to ionizing radiation gi|256000811|ref|NP_001157730.1|/0/X-ray radiation resistance-associated protein 1 [Mus musculus] 218476 5107 0.033333333 0.026666667 -0.321928095 Down 0.09684456 Gcnt4 "glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)" "K09663|1|0.0|835|mmu:218476|beta-1,6-N-acetylglucosaminyltransferase 4 [EC:2.4.1.-]" - - - - 207667 3597 0.036666667 0.046666667 0.347923303 Up 0.09684456 Skor1 SKI family transcriptional corepressor 1 K18499|1|5e-28|129|cmk:103185104|Ski-like protein - - - - 226143 1964 0.036666667 0.046666667 0.347923303 Up 0.09684456 Cyp2c44 "cytochrome P450, family 2, subfamily c, polypeptide 44" "K07413|1|0.0|815|mmu:226143|cytochrome P450, family 2, subfamily C [EC:1.14.14.1]" - - - - 70426 1774 0.043333333 0.033333333 -0.378511623 Down 0.09684456 Tekt5 tektin 5 K18632|1|0.0|845|mmu:70426|tektin-5 GO:0015630//microtubule cytoskeleton - - gi|597436962|ref|NP_001277930.1|/0/tektin-5 isoform 1 [Mus musculus] 218581 2530 0.06 0.046666667 -0.362570079 Down 0.09684456 Depdc1b DEP domain containing 1B - GO:0044444//cytoplasmic part GO:0008047//enzyme activator activity GO:0043087//regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction "gi|148686496|gb|EDL18443.1|/0/DEP domain containing 1B, isoform CRA_a, partial [Mus musculus]" 18164 5284 0.033333333 0.043333333 0.378511623 Up 0.09684456 Nptx1 neuronal pentraxin 1 K11453|1|8e-112|408|amj:102562598|chromobox protein 6;K17495|4|3e-33|147|rro:104664140|CUB and sushi domain-containing protein "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0042995//cell projection;GO:0016020//membrane" GO:0043169//cation binding GO:0001678//cellular glucose homeostasis;GO:0044765//single-organism transport;GO:0035864//response to potassium ion;GO:0007409//axonogenesis;GO:0000266//mitochondrial fission gi|6679120|ref|NP_032756.1|/0/neuronal pentraxin-1 precursor [Mus musculus] 381801 2646 17.86333333 17.97 0.008589094 Up 0.096656512 Tatdn2 TatD DNase domain containing 2 K03424|1|0.0|1325|mmu:381801|TatD DNase family protein [EC:3.1.21.-] - - - gi|153791422|ref|NP_001028635.2|/0/putative deoxyribonuclease TATDN2 [Mus musculus] 12842 5946 31.65666667 31.54666667 -0.00502178 Down 0.096656512 Col1a1 "collagen, type I, alpha 1" "K06236|1|5e-151|539|mmu:12842|collagen, type I, alpha" - - - - 12325 3685.55 14.27 14.16 -0.011164069 Down 0.096656512 Camk2g calcium/calmodulin-dependent protein kinase II gamma K04515|1|0.0|1021|tup:102503259|calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] GO:0031981//nuclear lumen;GO:0005789//endoplasmic reticulum membrane;GO:0030139//endocytic vesicle;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0005789//endoplasmic reticulum membrane;GO:0030139//endocytic vesicle;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0005789//endoplasmic reticulum membrane;GO:0030139//endocytic vesicle;GO:0043234//protein complex GO:0032550;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0032550;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0032550;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0004722//protein serine/threonine phosphatase activity GO:0048731//system development;GO:0044772//mitotic cell cycle phase transition;GO:0043501//skeletal muscle adaptation;GO:0006816//calcium ion transport;GO:0019221//cytokine-mediated signaling pathway;GO:0006468//protein phosphorylation;GO:0030072//peptide hormone secretion;GO:0048869//cellular developmental process;GO:0006950//response to stress;GO:0048731//system development;GO:0044772//mitotic cell cycle phase transition;GO:0043501//skeletal muscle adaptation;GO:0006816//calcium ion transport;GO:0019221//cytokine-mediated signaling pathway;GO:0006468//protein phosphorylation;GO:0030072//peptide hormone secretion;GO:0048869//cellular developmental process;GO:0006950//response to stress;GO:0048731//system development;GO:0044772//mitotic cell cycle phase transition;GO:0043501//skeletal muscle adaptation;GO:0006816//calcium ion transport;GO:0019221//cytokine-mediated signaling pathway;GO:0006468//protein phosphorylation;GO:0030072//peptide hormone secretion;GO:0048869//cellular developmental process;GO:0006950//response to stress gi|75991700|ref|NP_848712.2|/0/calcium/calmodulin-dependent protein kinase type II subunit gamma isoform 1 [Mus musculus] 68043 836 20.77 20.88 0.007620496 Up 0.096656512 Eef1akmt1 eukaryotic translation elongation factor 1 alpha lysine methyltransferase 1 - - - - - 11607 2284 16.37666667 16.48333333 0.009366282 Up 0.096656512 Agtr1a "angiotensin II receptor, type 1a" K04166|1|6e-172|607|mmu:11607|angiotensin II receptor type 1 - - - - 72722 2817 16.69333333 16.80666667 0.009761556 Up 0.096656512 Fam98a "family with sequence similarity 98, member A" K15434|1|5e-88|328|lcm:102347700|protein FAM98B - - - gi|532050432|ref|XP_005367982.1|/0/PREDICTED: protein FAM98A [Microtus ochrogaster] 56786 1685 23.60333333 23.71666667 0.00691064 Up 0.096656512 Tmem9b "TMEM9 domain family, member B" - GO:0031224//intrinsic component of membrane GO:0060089 GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|10092671|ref|NP_064434.1|/6.6645e-85/transmembrane protein 9B precursor [Mus musculus] 13864 2218 18.09333333 17.98333333 -0.008797761 Down 0.096656512 Nr2f6 "nuclear receptor subfamily 2, group F, member 6" K08549|1|0.0|638|mmu:13864|nuclear receptor subfamily 2 group F member 6 GO:0031981//nuclear lumen "GO:0046914//transition metal ion binding;GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0003677//DNA binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0009648//photoperiodism;GO:0019233//sensory perception of pain;GO:0030182//neuron differentiation gi|74145119|dbj|BAE27426.1|/2.03756e-180/unnamed protein product [Mus musculus] 229707 3248 12.22333333 12.33 0.012535034 Up 0.096656512 Strip1 striatin interacting protein 1 K19603|1|2e-10|71.2|smm:Smp_133500|mitogen-activated protein kinase 15 [EC:2.7.11.24] GO:0043231//intracellular membrane-bounded organelle - GO:0000902//cell morphogenesis;GO:0030036//actin cytoskeleton organization gi|672016215|ref|XP_001068288.3|/0/PREDICTED: striatin-interacting protein 1 [Rattus norvegicus] 67205 953 15.94 15.83333333 -0.009686617 Down 0.096656512 Utp11l "UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)" K14769|1|3e-132|473|mmu:67205|U3 small nucleolar RNA-associated protein 11 GO:0031981//nuclear lumen;GO:0030684//preribosome;GO:0044421 GO:0005488//binding GO:0012502//induction of programmed cell death;GO:0048731//system development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0042254//ribosome biogenesis gi|13385534|ref|NP_080307.1|/2.6578e-131/probable U3 small nucleolar RNA-associated protein 11 [Mus musculus] 20768 2206 15.16 15.05333333 -0.010186768 Down 0.096656512 Sephs2 selenophosphate synthetase 2 "K01008|1|0.0|708|mmu:20768|selenide, water dikinase [EC:2.7.9.3]" - GO:0016301//kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0009070//serine family amino acid biosynthetic process "gi|15011843|ref|NP_033292.2|/0/selenide, water dikinase 2 [Mus musculus]" 16551 4850 0.483333333 0.506666667 0.068018423 Up 0.096383843 Kif11 kinesin family member 11 K10398|1|0.0|1986|mmu:16551|kinesin family member 11 GO:0005819//spindle GO:0032550;GO:0019900//kinase binding;GO:0003774//motor activity;GO:0015631//tubulin binding GO:0007052//mitotic spindle organization;GO:0007067//mitotic nuclear division;GO:0006928//movement of cell or subcellular component "gi|148709842|gb|EDL41788.1|/0/kinesin family member 11, isoform CRA_b, partial [Mus musculus]" 67547 3383 0.433333333 0.453333333 0.065095028 Up 0.096383843 Slc39a8 "solute carrier family 39 (metal ion transporter), member 8" "K14714|1|0.0|889|mmu:67547|solute carrier family 39 (zinc transporter), member 8" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0008324//cation transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity;GO:0008324//cation transmembrane transporter activity GO:0000041//transition metal ion transport;GO:0044763;GO:0000041//transition metal ion transport;GO:0044763;GO:0000041//transition metal ion transport;GO:0044763 "gi|148680189|gb|EDL12136.1|/0/solute carrier family 39 (metal ion transporter), member 8, isoform CRA_a, partial [Mus musculus]" 77762 821 0.363333333 0.346666667 -0.067744607 Down 0.096383843 9930111H07Rik RIKEN cDNA 9930111H07 gene - - - - gi|148708310|gb|EDL40257.1|/5.27788e-31/mCG145600 [Mus musculus] 60361 1282 0.33 0.346666667 0.071083098 Up 0.096383843 Ms4a4b "membrane-spanning 4-domains, subfamily A, member 4B" K19928|1|1e-15|87.0|clv:102089886|zona pellucida sperm-binding protein 3 GO:0016020//membrane - - "gi|11096338|ref|NP_068364.1|/3.69476e-111/membrane-spanning 4-domains, subfamily A, member 4B [Mus musculus]" 18711 11255 0.466666667 0.49 0.070389328 Up 0.096383843 Pikfyve "phosphoinositide kinase, FYVE finger containing" K00921|1|0.0|3804|mmu:18711|1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150] - - - gi|50510739|dbj|BAD32355.1|/0/mKIAA0981 protein [Mus musculus] 19699 11696 0.343333333 0.36 0.068386975 Up 0.096383843 Reln reelin K06249|1|0.0|7111|mmu:19699|reelin [EC:3.4.21.-] GO:0043005//neuron projection;GO:0044424;GO:0043025//neuronal cell body;GO:0044421;GO:0031012//extracellular matrix;GO:0043005//neuron projection;GO:0044424;GO:0043025//neuronal cell body;GO:0044421;GO:0031012//extracellular matrix "GO:0004672//protein kinase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070325//lipoprotein particle receptor binding;GO:0043169//cation binding;GO:0004672//protein kinase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0070325//lipoprotein particle receptor binding;GO:0043169//cation binding" "GO:0021766//hippocampus development;GO:0009636//response to toxic substance;GO:0000902//cell morphogenesis;GO:0033555//multicellular organismal response to stress;GO:0009628//response to abiotic stimulus;GO:0021510//spinal cord development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:0051094//positive regulation of developmental process;GO:0007613//memory;GO:0009967//positive regulation of signal transduction;GO:0051705;GO:0031346//positive regulation of cell projection organization;GO:0035249//synaptic transmission, glutamatergic;GO:0010469//regulation of receptor activity;GO:0048565//digestive tract development;GO:0021536//diencephalon development;GO:0006935//chemotaxis;GO:0010975//regulation of neuron projection development;GO:0007612//learning;GO:0022610;GO:0007264//small GTPase mediated signal transduction;GO:0001101//response to acid chemical;GO:0071385//cellular response to glucocorticoid stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0010038//response to metal ion;GO:0035418//protein localization to synapse;GO:0003002//regionalization;GO:0072578//neurotransmitter-gated ion channel clustering;GO:0045838//positive regulation of membrane potential;GO:0045860//positive regulation of protein kinase activity;GO:0097305//response to alcohol;GO:0009611//response to wounding;GO:0021795//cerebral cortex cell migration;GO:0006575//cellular modified amino acid metabolic process;GO:0021766//hippocampus development;GO:0009636//response to toxic substance;GO:0000902//cell morphogenesis;GO:0033555//multicellular organismal response to stress;GO:0009628//response to abiotic stimulus;GO:0021510//spinal cord development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:0051094//positive regulation of developmental process;GO:0007613//memory;GO:0009967//positive regulation of signal transduction;GO:0051705;GO:0031346//positive regulation of cell projection organization;GO:0035249//synaptic transmission, glutamatergic;GO:0010469//regulation of receptor activity;GO:0048565//digestive tract development;GO:0021536//diencephalon development;GO:0006935//chemotaxis;GO:0010975//regulation of neuron projection development;GO:0007612//learning;GO:0022610;GO:0007264//small GTPase mediated signal transduction;GO:0001101//response to acid chemical;GO:0071385//cellular response to glucocorticoid stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0010038//response to metal ion;GO:0035418//protein localization to synapse;GO:0003002//regionalization;GO:0072578//neurotransmitter-gated ion channel clustering;GO:0045838//positive regulation of membrane potential;GO:0045860//positive regulation of protein kinase activity;GO:0097305//response to alcohol;GO:0009611//response to wounding;GO:0021795//cerebral cortex cell migration;GO:0006575//cellular modified amino acid metabolic process" gi|882939033|ref|NP_001297393.1|/0/reelin isoform 2 precursor [Mus musculus] 14396 3727 0.316666667 0.333333333 0.074000581 Up 0.096383843 Gabra3 "gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3" K05175|1|0.0|913|mmu:14396|gamma-aminobutyric acid receptor subunit alpha GO:0097060//synaptic membrane;GO:0034702//ion channel complex GO:0005253//anion channel activity;GO:0005488//binding;GO:0016917//GABA receptor activity;GO:0015276//ligand-gated ion channel activity GO:0007267//cell-cell signaling;GO:0015698//inorganic anion transport;GO:0007186//G-protein coupled receptor signaling pathway "gi|149027091|gb|EDL82833.1|/0/gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 3 [Rattus norvegicus]" 242681 735 0.486666667 0.463333333 -0.070883486 Down 0.096383843 Rab42 "RAB42, member RAS oncogene family" K07929|1|7e-122|438|mmu:242681|Ras-related protein Rab-42 - GO:0032550 - gi|112293053|dbj|BAF02904.1|/5.75225e-121/Rab43 [Mus musculus] 12828 8609 0.43 0.41 -0.06871275 Down 0.096383843 Col4a3 "collagen, type IV, alpha 3" "K06237|1|0.0|1160|mmu:12828|collagen, type IV, alpha" GO:0005576//extracellular region - GO:0048731//system development;GO:0044763;GO:0050794//regulation of cellular process;GO:0044767//single-organism developmental process gi|145699101|ref|NP_031760.2|/0/collagen alpha-3(IV) chain precursor [Mus musculus] 23984 7717 0.353333333 0.336666667 -0.069708972 Down 0.096383843 Pde10a phosphodiesterase 10A "K18438|1|0.0|1593|ngi:103735734|cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]" GO:0043025//neuronal cell body;GO:0044424;GO:0043025//neuronal cell body;GO:0044424 "GO:0043169//cation binding;GO:0030551//cyclic nucleotide binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0043169//cation binding;GO:0030551//cyclic nucleotide binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity" GO:0009154//purine ribonucleotide catabolic process;GO:0046058//cAMP metabolic process;GO:0009154//purine ribonucleotide catabolic process;GO:0046058//cAMP metabolic process "gi|595582115|ref|NP_001277636.1|/0/cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform 1 [Mus musculus]" 72713 2208 0.443333333 0.466666667 0.074000581 Up 0.096383843 Angptl1 angiopoietin-like 1 K05467|1|9e-56|221|oas:101107460|angiopoietin 4;K05465|2|6e-55|218|ocu:100342781|angiopoietin 1 GO:0044421 - GO:0007167//enzyme linked receptor protein signaling pathway gi|66792796|ref|NP_082609.2|/0/angiopoietin-related protein 1 precursor [Mus musculus] 18082 1874 0.366666667 0.35 -0.067114196 Down 0.096383843 Nipsnap1 nipsnap homolog 1 (C. elegans) K02D10.1;|1|5e-47|191|cel:CELE_K02D10.1|Putative NipSnap protein K02D10.1;K19269|1|5e-47|191|cel:CELE_K02D10.1|phosphoglycolate phosphatase [EC:3.1.3.18 3.1.3.48];K13174|3|1e-17|94.0|aam:106485346|THO complex subunit 5 GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0007600//sensory perception gi|6679066|ref|NP_032724.1|/4.22995e-168/protein NipSnap homolog 1 [Mus musculus] 240638 3870 0.486666667 0.51 0.067563284 Up 0.096383843 Slc16a12 "solute carrier family 16 (monocarboxylic acid transporters), member 12" "K11810|1|0.0|984|mmu:240638|MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 12" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0051234//establishment of localization;GO:0044763 gi|27370260|ref|NP_766426.1|/0/monocarboxylate transporter 12 [Mus musculus] 26367 3261.14 0.066666667 0.08 0.263034406 Up 0.096073564 Ceacam2 carcinoembryonic antigen-related cell adhesion molecule 2 K06499|1|5e-110|402|mmu:26367|carcinoembryonic antigen-related cell adhesion molecule - - - - 638580 718 0.076666667 0.063333333 -0.275634443 Down 0.096073564 Gm7244 predicted gene 7244 - GO:0031981//nuclear lumen - - gi|197304760|ref|NP_001095067.1|/2.23925e-66/uncharacterized protein LOC638580 [Mus musculus] 240058 4366 0.033333333 0.04 0.263034406 Up 0.096073564 Cpne5 copine V K11348|1|1e-33|145|apla:101800649|bromodomain and PHD finger-containing protein 1;K06491|3|8e-09|66.2|cin:100183448|neural cell adhesion molecule;K15290|4|2e-08|65.1|cel:CELE_F31E8.2|synaptotagmin-1;K19910|5|2e-08|64.7|ame:724220|synaptotagmin-10 GO:0044297//cell body;GO:0042995//cell projection - - gi|23346611|ref|NP_694806.1|/0/copine-5 [Mus musculus] 110326 2814 0.04 0.033333333 -0.263034406 Down 0.096073564 Tas1r1 "taste receptor, type 1, member 1" K04624|1|0.0|1628|mmu:110326|taste receptor type 1 member 1 GO:0031224//intrinsic component of membrane GO:0004930//G-protein coupled receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0050909//sensory perception of taste gi|13994192|ref|NP_114073.1|/0/taste receptor type 1 member 1 precursor [Mus musculus] 83558 3250 0.056666667 0.046666667 -0.280107919 Down 0.096073564 Tex11 testis expressed gene 11 - - - - - 353188 2247 0.05 0.06 0.263034406 Up 0.096073564 Adam32 a disintegrin and metallopeptidase domain 32 K16070|1|0.0|1471|mmu:353188|disintegrin and metalloproteinase domain-containing protein 32 [EC:3.4.24.-] - - - gi|656214619|ref|NP_001280622.1|/0/disintegrin and metalloproteinase domain-containing protein 32 isoform 2 precursor [Mus musculus] 13840 4213 0.03 0.036666667 0.289506617 Up 0.096073564 Epha6 Eph receptor A6 K05107|1|0.0|2100|mmu:13840|Eph receptor A6 [EC:2.7.10.1] GO:0016021//integral component of membrane GO:0032550;GO:0004714//transmembrane receptor protein tyrosine kinase activity GO:0006464//cellular protein modification process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006796//phosphate-containing compound metabolic process gi|145312274|ref|NP_031964.2|/0/ephrin type-A receptor 6 [Mus musculus] 320040 2701 0.056666667 0.07 0.304854582 Up 0.096073564 Rnf222 ring finger protein 222 K12026|1|6e-06|55.8|crg:105327122|tripartite motif-containing protein 56 [EC:2.3.2.27] GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding - gi|116089300|ref|NP_796034.2|/2.39325e-85/RING finger protein 222 [Mus musculus] 214321 2511 0.076666667 0.063333333 -0.275634443 Down 0.096073564 Gm4787 predicted gene 4787 K16069|1|3e-130|468|cfa:100687448|disintegrin and metalloproteinase domain-containing protein 29 [EC:3.4.24.-];K08609|4|2e-128|462|myd:102756663|disintegrin and metalloproteinase domain-containing protein 20 [EC:3.4.24.-] - - - - 75424 3695 0.043333333 0.053333333 0.299560282 Up 0.096073564 Zfp820 zinc finger protein 820 K09228|1|0.0|702|mmu:102632968|KRAB domain-containing zinc finger protein - - - gi|569001926|ref|XP_006525129.1|/0/PREDICTED: zinc finger protein 820 isoform X2 [Mus musculus] 14472 2126 0.056666667 0.07 0.304854582 Up 0.096073564 Gbx2 gastrulation brain homeobox 2 K09321|1|1e-170|602|mmu:14472|homeobox protein GBX GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0001525//angiogenesis;GO:0006351//transcription, DNA-templated;GO:0021536//diencephalon development;GO:0030917//midbrain-hindbrain boundary development;GO:0001667//ameboidal-type cell migration;GO:0021924//cell proliferation in external granule layer;GO:0021546//rhombomere development;GO:0021879//forebrain neuron differentiation;GO:0006935//chemotaxis;GO:0042471//ear morphogenesis;GO:0022037//metencephalon development" gi|524964733|ref|XP_005082278.1|/8.98752e-170/PREDICTED: homeobox protein GBX-2 [Mesocricetus auratus] 57340 3903 0.046666667 0.056666667 0.280107919 Up 0.096073564 Jph3 junctophilin 3 K19530|1|0.0|1270|mmu:57340|junctophilin GO:0031224//intrinsic component of membrane;GO:0016528//sarcoplasm;GO:0031090//organelle membrane GO:0005262//calcium channel activity GO:0050905//neuromuscular process;GO:1901019//regulation of calcium ion transmembrane transporter activity;GO:0007611//learning or memory;GO:0048167//regulation of synaptic plasticity gi|26350053|dbj|BAC38666.1|/0/unnamed protein product [Mus musculus] 229687 1605 0.04 0.033333333 -0.263034406 Down 0.096073564 Chil5 chitinase-like 5 K01183|1|0.0|671|cge:100750633|chitinase [EC:3.2.1.14] GO:0044424;GO:0044421 "GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0019899//enzyme binding;GO:0097367//carbohydrate derivative binding" GO:0012501//programmed cell death;GO:0051707//response to other organism;GO:0006954//inflammatory response;GO:0006026;GO:0002376//immune system process;GO:0042221//response to chemical;GO:0032722//positive regulation of chemokine production;GO:0005976//polysaccharide metabolic process;GO:0006030//chitin metabolic process gi|124249101|ref|NP_001074285.1|/0/chitinase like precursor [Mus musculus] 100134990 799 0.08 0.066666667 -0.263034406 Down 0.096073564 Gm12060 selenoprotein K pseudogene - - - - gi|344252869|gb|EGW08973.1|/3.60121e-21/Selenoprotein K [Cricetulus griseus] 382044 1965 0.033333333 0.04 0.263034406 Up 0.096073564 Ces1b carboxylesterase 1B K01044|1|0.0|911|mmu:13884|carboxylesterase 1 [EC:3.1.1.1] GO:0044421;GO:0044432 GO:0052689//carboxylic ester hydrolase activity - gi|124487013|ref|NP_001074841.1|/0/carboxylesterase 1B precursor [Mus musculus] 320775 1689 0.036666667 0.03 -0.289506617 Down 0.096073564 B230319C09Rik RIKEN cDNA B230319C09 gene - - - - "gi|148666665|gb|EDK99081.1|/1.40284e-66/mCG144880, partial [Mus musculus]" 78016 3807 0.03 0.036666667 0.289506617 Up 0.096073564 Ccdc150 coiled-coil domain containing 150 K15201|1|0.0|817|ssc:100154260|general transcription factor 3C polypeptide 3 (transcription factor C subunit 4);K20478|3|2e-46|191|dre:557772|golgin subfamily B member 1 - - - gi|229577139|ref|NP_084301.2|/0/coiled-coil domain-containing protein 150 [Mus musculus] 212124 8215 0.03 0.036666667 0.289506617 Up 0.096073564 Cfap46 cilia and flagella associated protein 46 - - - - - 22068 3235 0.03 0.036666667 0.289506617 Up 0.096073564 Trpc6 "transient receptor potential cation channel, subfamily C, member 6" K04969|1|0.0|706|mmu:22068|transient receptor potential cation channel subfamily C member 6 GO:0031224//intrinsic component of membrane;GO:0036056;GO:0031224//intrinsic component of membrane;GO:0036056;GO:0031224//intrinsic component of membrane;GO:0036056 GO:0005262//calcium channel activity;GO:0043168//anion binding;GO:0043168//anion binding;GO:0005262//calcium channel activity;GO:0043168//anion binding;GO:0005262//calcium channel activity GO:0007599//hemostasis;GO:0032411//positive regulation of transporter activity;GO:0006816//calcium ion transport;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0006935//chemotaxis;GO:0001775//cell activation;GO:0032411//positive regulation of transporter activity;GO:0006816//calcium ion transport;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0032411//positive regulation of transporter activity;GO:0006816//calcium ion transport;GO:0051480//regulation of cytosolic calcium ion concentration gi|530719558|ref|NP_001269015.1|/0/short transient receptor potential channel 6 isoform 2 [Mus musculus] 237625 2642 0.08 0.066666667 -0.263034406 Down 0.096073564 Pla2g3 "phospholipase A2, group III" K01047|1|0.0|1007|mmu:237625|secretory phospholipase A2 [EC:3.1.1.4] GO:0005813//centrosome - GO:0048858//cell projection morphogenesis gi|145207955|ref|NP_766379.2|/0/group 3 secretory phospholipase A2 precursor [Mus musculus] 12163 2366 0.046666667 0.056666667 0.280107919 Up 0.096073564 Bmp8a bone morphogenetic protein 8a K16622|1|0.0|670|mmu:12163|bone morphogenetic protein 8 GO:0044421;GO:0044421 GO:0005102//receptor binding;GO:0005102//receptor binding GO:0001501//skeletal system development;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0003006//developmental process involved in reproduction;GO:0048232//male gamete generation;GO:0048869//cellular developmental process;GO:0001501//skeletal system development;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0003006//developmental process involved in reproduction;GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|74192193|dbj|BAE34297.1|/0/unnamed protein product [Mus musculus] 320492 6181 0.063333333 0.076666667 0.275634443 Up 0.096073564 A830018L16Rik RIKEN cDNA A830018L16 gene - - GO:0019887//protein kinase regulator activity GO:0007154//cell communication gi|882939052|ref|NP_001297380.1|/0/uncharacterized protein C8orf34 homolog isoform 5 [Mus musculus] 66809 1948 0.06 0.05 -0.263034406 Down 0.096073564 Krt20 keratin 20 "K07604|1|0.0|736|mmu:66809|type I keratin, acidic" - - - - 58178 4396 0.046666667 0.056666667 0.280107919 Up 0.096073564 Sorcs1 sortilin-related VPS10 domain containing receptor 1 K12388|1|3e-64|251|mze:101465533|sortilin - - - - 12669 6209 0.07 0.056666667 -0.304854582 Down 0.096073564 Chrm1 "cholinergic receptor, muscarinic 1, CNS" K04129|1|0.0|767|ptg:102964850|muscarinic acetylcholine receptor M1 GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0016021//integral component of membrane;GO:0033267;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0016021//integral component of membrane;GO:0033267 GO:0008227//G-protein coupled amine receptor activity;GO:0004629//phospholipase C activity;GO:0005488//binding;GO:0008227//G-protein coupled amine receptor activity;GO:0004629//phospholipase C activity;GO:0005488//binding GO:0048731//system development;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0032388//positive regulation of intracellular transport;GO:0040011//locomotion;GO:0008283//cell proliferation;GO:0051899//membrane depolarization;GO:0007268//chemical synaptic transmission;GO:0036211//protein modification process;GO:0006811//ion transport;GO:0010517//regulation of phospholipase activity;GO:0048731//system development;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0032388//positive regulation of intracellular transport;GO:0040011//locomotion;GO:0008283//cell proliferation;GO:0051899//membrane depolarization;GO:0007268//chemical synaptic transmission;GO:0036211//protein modification process;GO:0006811//ion transport;GO:0010517//regulation of phospholipase activity gi|987420345|ref|XP_015397455.1|/0/PREDICTED: muscarinic acetylcholine receptor M1 [Panthera tigris altaica] 66011 5002 0.06 0.073333333 0.289506617 Up 0.096073564 Ranbp17 RAN binding protein 17 K18460|1|0.0|1499|lcm:102367484|exportin-7 GO:0005635//nuclear envelope;GO:0005635//nuclear envelope GO:0017016//Ras GTPase binding;GO:0022892//substrate-specific transporter activity;GO:0017016//Ras GTPase binding;GO:0022892//substrate-specific transporter activity GO:0050658//RNA transport;GO:0051169//nuclear transport;GO:0015031//protein transport;GO:0050658//RNA transport;GO:0051169//nuclear transport;GO:0015031//protein transport gi|13249349|ref|NP_075635.1|/0/ran-binding protein 17 [Mus musculus] 66890 4315 28.83666667 28.73666667 -0.005011683 Down 0.096035955 Lman2 "lectin, mannose-binding 2" "K10082|1|1e-175|620|mmu:66890|lectin, mannose-binding 2" GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0043169//cation binding GO:0045184//establishment of protein localization gi|34328278|ref|NP_080104.2|/9.43841e-175/vesicular integral-membrane protein VIP36 precursor [Mus musculus] 229285 3676.7 12.09 11.99 -0.011982586 Down 0.096035955 Spg20 "spastic paraplegia 20, spartin (Troyer syndrome) homolog (human)" K19366|1|0.0|1162|mmu:229285|spartin GO:0031966//mitochondrial membrane;GO:0031966//mitochondrial membrane;GO:0031966//mitochondrial membrane GO:0044389//ubiquitin-like protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0044389//ubiquitin-like protein ligase binding GO:0048669//collateral sprouting in absence of injury;GO:0048513//animal organ development;GO:0006996//organelle organization;GO:0050877//neurological system process;GO:0042391//regulation of membrane potential;GO:0030509//BMP signaling pathway;GO:0048669//collateral sprouting in absence of injury;GO:0048513//animal organ development;GO:0006996//organelle organization;GO:0050877//neurological system process;GO:0042391//regulation of membrane potential;GO:0030509//BMP signaling pathway;GO:0048669//collateral sprouting in absence of injury;GO:0048513//animal organ development;GO:0006996//organelle organization;GO:0050877//neurological system process;GO:0042391//regulation of membrane potential;GO:0030509//BMP signaling pathway gi|37360006|dbj|BAC97981.1|/0/mKIAA0610 protein [Mus musculus] 319197 2884 10.45666667 10.55333333 0.013275726 Up 0.096035955 Gpr4 G protein-coupled receptor 4 K04312|1|0.0|709|mmu:319197|G protein-coupled receptor 4 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|28316758|ref|NP_783599.1|/0/G-protein coupled receptor 4 [Mus musculus] 68970 3454 11.91666667 12.01666667 0.012056018 Up 0.096035955 Dcaf12 DDB1 and CUL4 associated factor 12 K11803|1|0.0|941|mmu:68970|WD repeat-containing protein 40A GO:0005815//microtubule organizing center;GO:0031461//cullin-RING ubiquitin ligase complex - GO:0032446//protein modification by small protein conjugation gi|50511163|dbj|BAD32567.1|/0/mKIAA1892 protein [Mus musculus] 209446 3158.33 10.40666667 10.30333333 -0.014396883 Down 0.096035955 Tfe3 transcription factor E3 K09105|1|0.0|637|mmu:209446|transcription factor E3 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0000975//regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity GO:0006955//immune response;GO:0007155//cell adhesion;GO:0002761//regulation of myeloid leukocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0002761//regulation of myeloid leukocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0002761//regulation of myeloid leukocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0002761//regulation of myeloid leukocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0002761//regulation of myeloid leukocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0007155//cell adhesion;GO:0002761//regulation of myeloid leukocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter gi|407728587|ref|NP_001258419.1|/4.44175e-180/transcription factor E3 isoform c [Mus musculus] 216233 2204.57 19.86333333 19.96666667 0.007485756 Up 0.096035955 Socs2 suppressor of cytokine signaling 2 K04695|1|8e-109|373|chx:102178979|suppressor of cytokine signaling 2 - GO:0005126//cytokine receptor binding;GO:0005126//cytokine receptor binding;GO:0005126//cytokine receptor binding;GO:0005126//cytokine receptor binding GO:0043627//response to estrogen;GO:0032446//protein modification by small protein conjugation;GO:0035264//multicellular organism growth;GO:0007259//JAK-STAT cascade;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044767//single-organism developmental process;GO:0007589//body fluid secretion;GO:0030182//neuron differentiation;GO:0043627//response to estrogen;GO:0032446//protein modification by small protein conjugation;GO:0035264//multicellular organism growth;GO:0007259//JAK-STAT cascade;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044767//single-organism developmental process;GO:0007589//body fluid secretion;GO:0030182//neuron differentiation;GO:0043627//response to estrogen;GO:0032446//protein modification by small protein conjugation;GO:0035264//multicellular organism growth;GO:0007259//JAK-STAT cascade;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044767//single-organism developmental process;GO:0007589//body fluid secretion;GO:0030182//neuron differentiation;GO:0043627//response to estrogen;GO:0032446//protein modification by small protein conjugation;GO:0035264//multicellular organism growth;GO:0007259//JAK-STAT cascade;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0044767//single-organism developmental process;GO:0007589//body fluid secretion;GO:0030182//neuron differentiation gi|488509226|ref|XP_004446793.1|/6.48193e-112/PREDICTED: suppressor of cytokine signaling 2 isoform X1 [Dasypus novemcinctus] 76425 4427.53 16.8 16.70333333 -0.008325196 Down 0.096035955 Gid8 GID complex subunit 8 - - - - - 73826 3249 10.45 10.55333333 0.014195812 Up 0.096035955 Poldip3 "polymerase (DNA-directed), delta interacting protein 3" K12881|1|7e-07|59.3|mde:101895626|THO complex subunit 4 GO:0043234//protein complex;GO:0016604//nuclear body GO:0003676//nucleic acid binding;GO:0036094//small molecule binding GO:0006412//translation gi|60359854|dbj|BAD90146.1|/0/mKIAA1649 protein [Mus musculus] 66682 2072 19.22 19.31666667 0.007237824 Up 0.096035955 Trappc5 trafficking protein particle complex 5 K20280|1|7e-89|330|umr:103681741|trafficking protein particle complex subunit 5 GO:0005801//cis-Golgi network - GO:0006810//transport "gi|148690000|gb|EDL21947.1|/5.0427e-109/trafficking protein particle complex 5, partial [Mus musculus]" 65961 1610 17.23666667 17.14 -0.008113695 Down 0.096035955 Utp3 UTP3 small subunit processome component K14767|1|1e-161|572|mmu:65961|U3 small nucleolar RNA-associated protein 3 GO:0031981//nuclear lumen - GO:0007417//central nervous system development gi|12061569|gb|AAF80256.2|AF155362_1/1.1941e-160/charged amino acid rich leucine zipper factor-1 [Mus musculus] 214932 1925 10.24 10.14333333 -0.013683882 Down 0.096035955 Cecr5 "cat eye syndrome chromosome region, candidate 5" - GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity - gi|21450187|ref|NP_659064.1|/0/cat eye syndrome critical region protein 5 homolog precursor [Mus musculus] 15932 4430 9.27 9.366666667 0.014966386 Up 0.096035955 Idua "iduronidase, alpha-L-" K01217|1|0.0|1150|mmu:15932|L-iduronidase [EC:3.2.1.76] - - - gi|575403054|ref|NP_766585.1|/0/alpha-L-iduronidase isoform 2 precursor [Mus musculus] 60532 2632.63 15.60333333 15.70666667 0.009522774 Up 0.096035955 Wtap Wilms tumour 1-associating protein - GO:0005635//nuclear envelope;GO:0031981//nuclear lumen - GO:0044763;GO:0032502//developmental process;GO:0006396//RNA processing "gi|148670075|gb|EDL02022.1|/2.19823e-90/mCG16685, isoform CRA_c [Mus musculus]" 69207 3082.45 17.08333333 16.98666667 -0.008186727 Down 0.096035955 Srsf11 serine/arginine-rich splicing factor 11 "K12899|1|2e-81|306|mmu:69207|splicing factor, arginine/serine-rich 11" GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - - gi|148222073|ref|NP_001087221.1|/2.69789e-88/serine/arginine-rich splicing factor 11 isoform 2 [Mus musculus] 18457 3494 10.31 10.21 -0.014061466 Down 0.096035955 Bloc1s6 "biogenesis of lysosomal organelles complex-1, subunit 6, pallidin" K20188|1|5e-69|265|mmu:18457|biogenesis of lysosome-related organelles complex 1 subunit 6 "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0044425;GO:0031082" GO:0003779//actin binding;GO:0042802//identical protein binding GO:0007599//hemostasis;GO:0045597//positive regulation of cell differentiation;GO:0032401//establishment of melanosome localization;GO:0030101//natural killer cell activation;GO:0009306//protein secretion;GO:0006887//exocytosis;GO:0048489//synaptic vesicle transport;GO:0030030//cell projection organization;GO:0043485//endosome to pigment granule transport;GO:0008088//axo-dendritic transport gi|9790039|ref|NP_062762.1|/4.66219e-68/biogenesis of lysosome-related organelles complex 1 subunit 6 [Mus musculus] 68693 5726 16.67333333 16.77333333 0.008626865 Up 0.096035955 Hnrnpul2 heterogeneous nuclear ribonucleoprotein U-like 2 K12888|1|1e-125|454|ssc:100515571|heterogeneous nuclear ribonucleoprotein U GO:0043231//intracellular membrane-bounded organelle - - gi|124487099|ref|NP_001074665.1|/0/heterogeneous nuclear ribonucleoprotein U-like protein 2 [Mus musculus] 75007 2846.1 12.74 12.64666667 -0.0106081 Down 0.095490616 Fam63a "family with sequence similarity 63, member A" - - - - gi|300934856|ref|NP_955769.1|/0/protein FAM63A isoform 1 [Mus musculus] 68991 1478 19.09333333 19.18333333 0.006784436 Up 0.095490616 Ssu72 Ssu72 RNA polymerase II CTD phosphatase homolog (yeast) K15544|1|3e-111|404|mmu:68991|RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16] GO:0043231//intracellular membrane-bounded organelle GO:0004722//protein serine/threonine phosphatase activity GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0031124//mRNA 3'-end processing gi|172088095|ref|NP_081175.2|/2.25175e-110/RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [Mus musculus] 83965 2516.64 9.113333333 9.2 0.013655024 Up 0.095490616 Enpp5 ectonucleotide pyrophosphatase/phosphodiesterase 5 K18398|1|0.0|994|mmu:83965|ectonucleotide pyrophosphatase/phosphodiesterase family member 5 [EC:3.1.-.-] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0044763;GO:0044763 gi|14030779|ref|NP_114392.1|/0/ectonucleotide pyrophosphatase/phosphodiesterase family member 5 precursor [Mus musculus] 74080 2160 11.00333333 11.09666667 0.012185732 Up 0.095490616 Nmnat3 nicotinamide nucleotide adenylyltransferase 3 K06210|1|2e-140|502|mmu:74080|nicotinamide mononucleotide adenylyltransferase [EC:2.7.7.1 2.7.7.18] - - - - 230126 2762 11.66 11.75333333 0.011502185 Up 0.095490616 Shb src homology 2 domain-containing transforming protein B K19862|1|2e-09|67.4|hmg:100201881|NCK adaptor protein 2;K04352|2|2e-07|61.2|crg:105329469|Ras GTPase-activating protein 1;K06619|3|2e-07|60.8|sko:100374571|abelson tyrosine-protein kinase 1 [EC:2.7.10.2] - - GO:0048731//system development;GO:0044763;GO:0044767//single-organism developmental process;GO:0002376//immune system process "gi|37747535|gb|AAH58986.1|/0/Shb protein, partial [Mus musculus]" 269378 2560 11.53333333 11.62 0.010800532 Up 0.095490616 Ahcy S-adenosylhomocysteine hydrolase K01251|1|0.0|863|mmu:11615|adenosylhomocysteinase [EC:3.3.1.1] GO:0042995//cell projection;GO:0048770 GO:0016802;GO:0046914//transition metal ion binding;GO:0017076//purine nucleotide binding;GO:0005515//protein binding GO:0042219//cellular modified amino acid catabolic process;GO:0002437//inflammatory response to antigenic stimulus;GO:0031667//response to nutrient levels;GO:0048512//circadian behavior "gi|148674161|gb|EDL06108.1|/0/mCG21063, isoform CRA_b, partial [Mus musculus]" 234594 8369.34 11.45333333 11.54333333 0.011292351 Up 0.095490616 Cnot1 "CCR4-NOT transcription complex, subunit 1" K12604|1|0.0|4412|mmu:234594|CCR4-NOT transcription complex subunit 1 GO:0035770//ribonucleoprotein granule;GO:0043234//protein complex;GO:0044439;GO:0035770//ribonucleoprotein granule;GO:0043234//protein complex;GO:0044439;GO:0035770//ribonucleoprotein granule;GO:0043234//protein complex;GO:0044439 GO:0035258//steroid hormone receptor binding;GO:0008134//transcription factor binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0035258//steroid hormone receptor binding;GO:0008134//transcription factor binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0035258//steroid hormone receptor binding;GO:0008134//transcription factor binding;GO:0000175//3'-5'-exoribonuclease activity "GO:0006351//transcription, DNA-templated;GO:0061014//positive regulation of mRNA catabolic process;GO:0009968//negative regulation of signal transduction;GO:0051239;GO:0010603//regulation of cytoplasmic mRNA processing body assembly;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006351//transcription, DNA-templated;GO:0061014//positive regulation of mRNA catabolic process;GO:0009968//negative regulation of signal transduction;GO:0051239;GO:0010603//regulation of cytoplasmic mRNA processing body assembly;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006351//transcription, DNA-templated;GO:0061014//positive regulation of mRNA catabolic process;GO:0009968//negative regulation of signal transduction;GO:0051239;GO:0010603//regulation of cytoplasmic mRNA processing body assembly;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening" gi|327315392|ref|NP_001192155.1|/0/CCR4-NOT transcription complex subunit 1 isoform 3 [Mus musculus] 14105 3077.36 9.593333333 9.5 -0.014104673 Down 0.095490616 Srsf10 serine/arginine-rich splicing factor 10 K12900|1|2e-61|240|bacu:102999791|FUS-interacting serine-arginine-rich protein 1 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding GO:0000245//spliceosomal complex assembly;GO:0016482//cytosolic transport;GO:0000245//spliceosomal complex assembly;GO:0016482//cytosolic transport;GO:0000245//spliceosomal complex assembly;GO:0016482//cytosolic transport;GO:0000245//spliceosomal complex assembly;GO:0046907//intracellular transport gi|5730079|ref|NP_006616.1|/1.57588e-60/serine/arginine-rich splicing factor 10 isoform 1 [Homo sapiens] 66948 2865 12.57666667 12.66666667 0.010287318 Up 0.095490616 Acad8 "acyl-Coenzyme A dehydrogenase family, member 8" K11538|1|0.0|828|mmu:66948|isobutyryl-CoA dehydrogenase [EC:1.3.99.-] GO:0043231//intracellular membrane-bounded organelle GO:0016491//oxidoreductase activity;GO:0000166//nucleotide binding GO:0009063//cellular amino acid catabolic process "gi|118403322|ref|NP_080138.2|/0/isobutyryl-CoA dehydrogenase, mitochondrial precursor [Mus musculus]" 66810 2079 16.80666667 16.71333333 -0.008034122 Down 0.095490616 Rbm22 RNA binding motif protein 22 K12872|1|0.0|742|pale:102890856|pre-mRNA-splicing factor RBM22/SLT11 GO:0005681//spliceosomal complex;GO:0031981//nuclear lumen GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0005215//transporter activity;GO:0036094//small molecule binding "GO:0006606//protein import into nucleus;GO:0000398//mRNA splicing, via spliceosome;GO:0032388//positive regulation of intracellular transport;GO:0006950//response to stress" gi|821411665|ref|XP_012392391.1|/0/PREDICTED: pre-mRNA-splicing factor RBM22 isoform X1 [Orcinus orca] 22042 4920 9.06 8.97 -0.014403065 Down 0.095490616 Tfrc transferrin receptor K06503|1|0.0|1524|mmu:22042|transferrin receptor GO:0009986//cell surface;GO:0048770;GO:0031224//intrinsic component of membrane;GO:0012505//endomembrane system;GO:0010008//endosome membrane GO:0038024//cargo receptor activity;GO:0016787//hydrolase activity;GO:0022890//inorganic cation transmembrane transporter activity;GO:0031072//heat shock protein binding GO:0032846;GO:0002526//acute inflammatory response;GO:0002573//myeloid leukocyte differentiation;GO:0006826//iron ion transport;GO:0016192//vesicle-mediated transport;GO:0010038//response to metal ion;GO:0033993//response to lipid;GO:0031667//response to nutrient levels;GO:0006875//cellular metal ion homeostasis;GO:0019538//protein metabolic process gi|11596855|ref|NP_035768.1|/0/transferrin receptor protein 1 [Mus musculus] 14615 2009.05 10.64333333 10.73666667 0.012596108 Up 0.095490616 Gjc1 "gap junction protein, gamma 1" "K07616|1|0.0|704|cge:100689357|gap junction protein, alpha 7" GO:0031224//intrinsic component of membrane;GO:0005921//gap junction;GO:0031224//intrinsic component of membrane;GO:0005921//gap junction;GO:0031224//intrinsic component of membrane;GO:0005921//gap junction GO:0005488//binding;GO:0022829//wide pore channel activity;GO:0015075//ion transmembrane transporter activity;GO:0005488//binding;GO:0022829//wide pore channel activity;GO:0015075//ion transmembrane transporter activity;GO:0005488//binding;GO:0022829//wide pore channel activity;GO:0015075//ion transmembrane transporter activity GO:0007267//cell-cell signaling;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0050953//sensory perception of light stimulus;GO:0007507//heart development;GO:0006811//ion transport;GO:0030154//cell differentiation;GO:0007267//cell-cell signaling;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0050953//sensory perception of light stimulus;GO:0007507//heart development;GO:0006811//ion transport;GO:0030154//cell differentiation;GO:0007267//cell-cell signaling;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0050953//sensory perception of light stimulus;GO:0007507//heart development;GO:0006811//ion transport;GO:0030154//cell differentiation gi|6680007|ref|NP_032148.1|/0/gap junction gamma-1 protein [Mus musculus] 67040 4444.31 21.81333333 21.90333333 0.005940194 Up 0.095490616 Ddx17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 K13178|1|0.0|1126|aml:100482324|ATP-dependent RNA helicase DDX17 [EC:3.6.4.13] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle "GO:0032550;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0004386//helicase activity;GO:0035258//steroid hormone receptor binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0004386//helicase activity;GO:0035258//steroid hormone receptor binding;GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0004386//helicase activity;GO:0035258//steroid hormone receptor binding;GO:0042623//ATPase activity, coupled;GO:1901363//heterocyclic compound binding;GO:0003712//transcription cofactor activity;GO:0016787//hydrolase activity;GO:0035258//steroid hormone receptor binding;GO:0097159//organic cyclic compound binding" GO:0006366//transcription from RNA polymerase II promoter;GO:0035914//skeletal muscle cell differentiation;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0035914//skeletal muscle cell differentiation;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0035914//skeletal muscle cell differentiation;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0035914//skeletal muscle cell differentiation;GO:0030520//intracellular estrogen receptor signaling pathway gi|731199320|ref|XP_010611222.1|/1.17335e-96/PREDICTED: LOW QUALITY PROTEIN: probable ATP-dependent RNA helicase DDX17 [Fukomys damarensis] 319934 7163 8.39 8.303333333 -0.014980195 Down 0.095490616 Sbf2 SET binding factor 2 K18061|1|0.0|3649|mmu:319934|myotubularin-related protein 5/13 - GO:0042802//identical protein binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0042578//phosphoric ester hydrolase activity;GO:0005543//phospholipid binding;GO:0019899//enzyme binding GO:0051259//protein oligomerization gi|256355198|ref|NP_796298.2|/0/myotubularin-related protein 13 [Mus musculus] 72046 5197.79 18.67666667 18.76666667 0.00693543 Up 0.095490616 Urgcp upregulator of cell proliferation K06551|1|8e-91|338|xtr:101733039|signal-regulatory protein alpha/beta1/gamma;K12797|2|1e-54|218|mdo:100018349|caspase recruitment domain-containing protein 6 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0032550 GO:0044763;GO:0044763 gi|117938770|ref|NP_848738.2|/0/up-regulator of cell proliferation isoform 1 [Mus musculus] 66233 1543 14.97666667 15.06333333 0.008324495 Up 0.095490616 Dmap1 DNA methyltransferase 1-associated protein 1 K11324|1|0.0|729|mmu:66233|DNA methyltransferase 1-associated protein 1 GO:0044427;GO:0043189//H4/H2A histone acetyltransferase complex GO:0003712//transcription cofactor activity;GO:0016741;GO:0001085//RNA polymerase II transcription factor binding GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0006259//DNA metabolic process;GO:0016573//histone acetylation;GO:0042307//positive regulation of protein import into nucleus gi|444721414|gb|ELW62151.1|/0/DNA methyltransferase 1-associated protein 1 [Tupaia chinensis] 67955 1951 15.24333333 15.15666667 -0.008225915 Down 0.095490616 Sugt1 "SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)" K12795|1|7e-180|633|mmu:67955|suppressor of G2 allele of SKP1 - - - - 20181 5168.26 24.73333333 24.64666667 -0.005064143 Down 0.095490616 Rxra retinoid X receptor alpha K08524|1|0.0|839|mmu:20181|retinoid X receptor alpha GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0000785//chromatin GO:0003708//retinoic acid receptor activity;GO:0008134//transcription factor binding;GO:0043566//structure-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003682//chromatin binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity;GO:0003708//retinoic acid receptor activity;GO:0008134//transcription factor binding;GO:0043566//structure-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003682//chromatin binding;GO:0046914//transition metal ion binding;GO:0046983//protein dimerization activity GO:0055007//cardiac muscle cell differentiation;GO:0032868//response to insulin;GO:0006915//apoptotic process;GO:0010035//response to inorganic substance;GO:0043009//chordate embryonic development;GO:0006952//defense response;GO:0042552//myelination;GO:0031960//response to corticosteroid;GO:0048565//digestive tract development;GO:0007409//axonogenesis;GO:0060442//branching involved in prostate gland morphogenesis;GO:0030522//intracellular receptor signaling pathway;GO:0001890//placenta development;GO:0006366//transcription from RNA polymerase II promoter;GO:0002067//glandular epithelial cell differentiation;GO:0009755//hormone-mediated signaling pathway;GO:0001525//angiogenesis;GO:0033273//response to vitamin;GO:0014855;GO:0097305//response to alcohol;GO:0003208//cardiac ventricle morphogenesis;GO:0055007//cardiac muscle cell differentiation;GO:0032868//response to insulin;GO:0006915//apoptotic process;GO:0010035//response to inorganic substance;GO:0043009//chordate embryonic development;GO:0006952//defense response;GO:0042552//myelination;GO:0031960//response to corticosteroid;GO:0048565//digestive tract development;GO:0007409//axonogenesis;GO:0060442//branching involved in prostate gland morphogenesis;GO:0030522//intracellular receptor signaling pathway;GO:0001890//placenta development;GO:0006366//transcription from RNA polymerase II promoter;GO:0002067//glandular epithelial cell differentiation;GO:0009755//hormone-mediated signaling pathway;GO:0001525//angiogenesis;GO:0033273//response to vitamin;GO:0014855;GO:0097305//response to alcohol;GO:0003208//cardiac ventricle morphogenesis gi|6755384|ref|NP_035435.1|/0/retinoic acid receptor RXR-alpha isoform 1 [Mus musculus] 102791 1800.12 18.86 18.77 -0.006901026 Down 0.095490616 Tcta T cell leukemia translocation altered gene - - - - - 215789 8328.32 8.64 8.726666667 0.014399379 Up 0.095490616 Phactr2 phosphatase and actin regulator 2 K17585|1|2e-78|298|gga:421667|phosphatase and actin regulator 4 - - - gi|84781783|ref|NP_001028429.1|/0/phosphatase and actin regulator 2 isoform D [Mus musculus] 11517 6262 1.163333333 1.19 0.032697038 Up 0.095311971 Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 K04587|1|0.0|963|mmu:11517|pituitary adenylate cyclase-activating polypeptide type I receptor GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0042995//cell projection;GO:0005783//endoplasmic reticulum;GO:0044459;GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0042995//cell projection;GO:0005783//endoplasmic reticulum;GO:0044459 GO:0004930//G-protein coupled receptor activity;GO:0031267//small GTPase binding;GO:0042277//peptide binding;GO:0004930//G-protein coupled receptor activity;GO:0031267//small GTPase binding;GO:0042277//peptide binding GO:0007166//cell surface receptor signaling pathway;GO:0010676;GO:0045137//development of primary sexual characteristics;GO:0043627//response to estrogen;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0010863//positive regulation of phospholipase C activity;GO:0006171//cAMP biosynthetic process;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0008219//cell death;GO:0097305//response to alcohol;GO:0010522//regulation of calcium ion transport into cytosol;GO:0006950//response to stress;GO:0007166//cell surface receptor signaling pathway;GO:0010676;GO:0045137//development of primary sexual characteristics;GO:0043627//response to estrogen;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0010863//positive regulation of phospholipase C activity;GO:0006171//cAMP biosynthetic process;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0008219//cell death;GO:0097305//response to alcohol;GO:0010522//regulation of calcium ion transport into cytosol;GO:0006950//response to stress gi|70780370|ref|NP_001020543.1|/0/pituitary adenylate cyclase-activating polypeptide type I receptor isoform 2 precursor [Mus musculus] 236069 774 0.396666667 0.413333333 0.059378547 Up 0.095311971 Gm13238 carnitine deficiency-associated gene expressed in ventricle 3 pseudogene - GO:0043231//intracellular membrane-bounded organelle - - gi|38328181|gb|AAH62156.1|/7.17063e-96/Cdv3 protein [Mus musculus] 242557 3108.32 1.32 1.346666667 0.028854863 Up 0.095311971 Atg4c "autophagy related 4C, cysteine peptidase" K08342|1|0.0|941|mmu:242557|cysteine protease ATG4 [EC:3.4.22.-] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0004175//endopeptidase activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process;GO:0006605//protein targeting;GO:0044248;GO:0007033//vacuole organization;GO:0019538//protein metabolic process;GO:0006605//protein targeting;GO:0044248;GO:0007033//vacuole organization "gi|148698945|gb|EDL30892.1|/0/autophagy-related 4C (yeast), isoform CRA_b, partial [Mus musculus]" 268932 6190 0.406666667 0.423333333 0.057947349 Up 0.095311971 Caskin1 CASK interacting protein 1 K14459|1|1e-47|191|apla:101799820|hexosaminidase [EC:3.2.1.52];K15503|4|4e-33|147|aag:AaeL_AAEL014668|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B GO:0044424 GO:0005515//protein binding GO:0007154//cell communication gi|161168996|ref|NP_082213.2|/0/caskin-1 [Mus musculus] 69028 1229 1.713333333 1.683333333 -0.025484972 Down 0.095311971 Mitd1 "MIT, microtubule interacting and transport, domain containing 1" - GO:0005770//late endosome;GO:0044425 - GO:0045184//establishment of protein localization;GO:0000920//cell separation after cytokinesis gi|12837824|dbj|BAB23964.1|/1.99824e-143/unnamed protein product [Mus musculus] 233893 2471 1.61 1.58 -0.02713613 Down 0.095311971 Zfp764 zinc finger protein 764 K09228|1|0.0|738|mmu:105243102|KRAB domain-containing zinc finger protein - - - gi|268370257|ref|NP_666315.3|/0/zinc finger protein 764 isoform 1 [Mus musculus] 240660 3471 1.626666667 1.596666667 -0.026855492 Down 0.095311971 Slc35g1 "solute carrier family 35, member G1" - GO:0031224//intrinsic component of membrane - - gi|30425262|ref|NP_780716.1|/5.85363e-180/solute carrier family 35 member G1 [Mus musculus] 12648 7918 1.676666667 1.71 0.028400426 Up 0.095311971 Chd1 chromodomain helicase DNA binding protein 1 K11367|1|0.0|2787|mmu:12648|chromodomain-helicase-DNA-binding protein 1 [EC:3.6.4.12] GO:0043231//intracellular membrane-bounded organelle GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0042393//histone binding;GO:0003676//nucleic acid binding "GO:0016568//chromatin modification;GO:0006351//transcription, DNA-templated" gi|455015|gb|AAB08486.1|/0/DNA-binding protein [Mus musculus] 23885 2967 1.343333333 1.316666667 -0.028927185 Down 0.095311971 Gmcl1 "germ cell-less, spermatogenesis associated 1" K10485|1|0.0|1001|mmu:23885|BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1) - - - - 72128 4229 1.556666667 1.586666667 0.027539024 Up 0.095311971 2610008E11Rik RIKEN cDNA 2610008E11 gene K09228|1|0.0|1469|mmu:72128|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|140971855|ref|NP_001004362.2|/0/uncharacterized protein LOC72128 [Mus musculus] 74039 3888.48 1.45 1.48 0.029544276 Up 0.095311971 Nfam1 Nfat activating molecule with ITAM motif 1 - GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464 GO:0038023//signaling receptor activity;GO:0038023//signaling receptor activity;GO:0038023//signaling receptor activity;GO:0038023//signaling receptor activity;GO:0038023//signaling receptor activity GO:0050853//B cell receptor signaling pathway;GO:0044093;GO:0030183//B cell differentiation;GO:0050853//B cell receptor signaling pathway;GO:0044093;GO:0030183//B cell differentiation;GO:0050853//B cell receptor signaling pathway;GO:0044093;GO:0030183//B cell differentiation;GO:0050853//B cell receptor signaling pathway;GO:0044093;GO:0030183//B cell differentiation;GO:0050853//B cell receptor signaling pathway;GO:0044093;GO:0030183//B cell differentiation gi|27229169|ref|NP_083004.1|/9.26187e-126/NFAT activation molecule 1 isoform d [Mus musculus] 17957 3693 0.523333333 0.503333333 -0.05621601 Down 0.095311971 Napb N-ethylmaleimide sensitive fusion protein attachment protein beta K15296|1|1e-140|504|gga:100858304|alpha-soluble NSF attachment protein GO:0031201//SNARE complex GO:0000149//SNARE binding GO:0007270//neuron-neuron synaptic transmission;GO:0016082//synaptic vesicle priming;GO:0015031//protein transport gi|29789104|ref|NP_062606.1|/1.1909e-162/beta-soluble NSF attachment protein [Mus musculus] 73390 2140 0.59 0.613333333 0.055956406 Up 0.095311971 Msl3l2 male-specific lethal 3-like 2 (Drosophila) K18403|1|2e-138|495|mmu:73390|male-specific lethal 3 GO:0005634//nucleus GO:0005488//binding "GO:0016568//chromatin modification;GO:0006351//transcription, DNA-templated" gi|255652855|ref|NP_001157305.1|/2.03536e-137/male-specific lethal 3-like 2 [Mus musculus] 100038514 896 0.45 0.47 0.062735755 Up 0.095311971 Gm11837 predicted gene 11837 - - - - gi|755505878|ref|XP_011248190.1|/1.28069e-68/PREDICTED: uncharacterized protein C8orf88 homolog isoform X2 [Mus musculus] 245350 1680 0.51 0.49 -0.057715498 Down 0.095311971 AA414768 expressed sequence AA414768 K10582|1|0.0|653|mmu:245350|ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23] - - - - 14462 3257 0.42 0.403333333 -0.058416686 Down 0.095311971 Gata3 GATA binding protein 3 K17895|1|0.0|706|mmu:14462|GATA-binding protein 3 GO:0031981//nuclear lumen;GO:0000785//chromatin "GO:0003712//transcription cofactor activity;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0046872//metal ion binding;GO:0005126//cytokine receptor binding;GO:0019904//protein domain specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding" "GO:0061209;GO:0006590//thyroid hormone generation;GO:0033598//mammary gland epithelial cell proliferation;GO:0040013//negative regulation of locomotion;GO:0050900//leukocyte migration;GO:0070670//response to interleukin-4;GO:0048483//autonomic nervous system development;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0002573//myeloid leukocyte differentiation;GO:0003382//epithelial cell morphogenesis;GO:0003176//aortic valve development;GO:0045444//fat cell differentiation;GO:0050851//antigen receptor-mediated signaling pathway;GO:0097305//response to alcohol;GO:0043066//negative regulation of apoptotic process;GO:0010594//regulation of endothelial cell migration;GO:0051726//regulation of cell cycle;GO:0008406//gonad development;GO:0006935//chemotaxis;GO:0043010//camera-type eye development;GO:0003208//cardiac ventricle morphogenesis;GO:0006954//inflammatory response;GO:0060986;GO:0043009//chordate embryonic development;GO:0010212//response to ionizing radiation;GO:0002320//lymphoid progenitor cell differentiation;GO:0051707//response to other organism;GO:0001819//positive regulation of cytokine production;GO:0001818//negative regulation of cytokine production;GO:0001838//embryonic epithelial tube formation;GO:0032633//interleukin-4 production;GO:0031060//regulation of histone methylation;GO:0048545//response to steroid hormone;GO:0042092//type 2 immune response;GO:0033077//T cell differentiation in thymus;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0042471//ear morphogenesis;GO:0035270//endocrine system development;GO:0042592//homeostatic process;GO:0001656//metanephros development;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048799;GO:0032609//interferon-gamma production;GO:0045165//cell fate commitment;GO:0040007//growth;GO:0042415//norepinephrine metabolic process;GO:0035455//response to interferon-alpha;GO:0034612//response to tumor necrosis factor;GO:0050715//positive regulation of cytokine secretion;GO:0051094//positive regulation of developmental process;GO:0072160//nephron tubule epithelial cell differentiation;GO:0043388//positive regulation of DNA binding;GO:0006366//transcription from RNA polymerase II promoter;GO:0043367//CD4-positive, alpha-beta T cell differentiation;GO:0002456//T cell mediated immunity" gi|6679951|ref|NP_032117.1|/0/trans-acting T-cell-specific transcription factor GATA-3 [Mus musculus] 54711 5407 1.733333333 1.7 -0.028014376 Down 0.095311971 Plagl2 pleiomorphic adenoma gene-like 2 K19486|1|0.0|870|pps:100974632|zinc finger protein PLAGL2 GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0003677//DNA binding" GO:0012502//induction of programmed cell death;GO:0034377//plasma lipoprotein particle assembly;GO:0007275//multicellular organism development;GO:0006366//transcription from RNA polymerase II promoter gi|296481295|tpg|DAA23410.1|/0/TPA: pleiomorphic adenoma gene-like 2 [Bos taurus] 53883 10543 1.55 1.58 0.027656343 Up 0.095311971 Celsr2 "cadherin, EGF LAG seven-pass G-type receptor 2" K04601|1|0.0|5472|mmu:53883|cadherin EGF LAG seven-pass G-type receptor 2 - - - - 17948 4782 0.463333333 0.483333333 0.060968017 Up 0.095311971 Naip2 "NLR family, apoptosis inhibitory protein 2" K12807|1|0.0|2870|mmu:17948|baculoviral IAP repeat-containing protein 1 GO:0043234//protein complex;GO:0044459;GO:0044424;GO:0043234//protein complex;GO:0044459;GO:0044424 GO:0043169//cation binding;GO:0032550;GO:0016462//pyrophosphatase activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0043169//cation binding;GO:0032550;GO:0016462//pyrophosphatase activity;GO:0004869//cysteine-type endopeptidase inhibitor activity GO:0006952//defense response;GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0051346//negative regulation of hydrolase activity;GO:0009581;GO:0006952//defense response;GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0051346//negative regulation of hydrolase activity;GO:0009581 gi|187133241|ref|NP_035002.2|/0/baculoviral IAP repeat-containing protein 1b [Mus musculus] 226610 4768.37 1.56 1.526666667 -0.031160931 Down 0.095311971 Fam78b "family with sequence similarity 78, member B" - - - - gi|63003925|ref|NP_780670.2|/5.13313e-150/protein FAM78B [Mus musculus] 74032 2835 1.493333333 1.463333333 -0.029277793 Down 0.095311971 Sdr42e1 "short chain dehydrogenase/reductase family 42E, member 1" K07748|1|3e-43|179|xma:102221009|sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) [EC:1.1.1.170] GO:0031224//intrinsic component of membrane "GO:0033764//steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0008202//steroid metabolic process gi|21311981|ref|NP_083001.1|/0/short-chain dehydrogenase/reductase family 42E member 1 [Mus musculus] 383348 1365 0.043333333 0.036666667 -0.2410081 Down 0.095255557 Kctd16 potassium channel tetramerisation domain containing 16 "K03849|1|2e-16|89.4|cmk:103177229|alpha-1,3-glucosyltransferase [EC:2.4.1.265];K15074|2|1e-09|67.0|tad:TRIADDRAFT_4579|BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein;K20131|3|1e-09|67.0|cmy:102940364|Rab5 GDP/GTP exchange factor;K11835|4|6e-09|64.7|sko:100377510|ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.4.19.12]" - - - gi|247494171|ref|NP_080411.1|/0/BTB/POZ domain-containing protein KCTD16 [Mus musculus] 13848 3756.06 0.053333333 0.063333333 0.247927513 Up 0.095255557 Ephb6 Eph receptor B6 K05114|1|0.0|1837|mmu:13848|Eph receptor B6 [EC:2.7.10.1] GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0032550;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0032550;GO:0004714//transmembrane receptor protein tyrosine kinase activity GO:0060986;GO:0055065//metal ion homeostasis;GO:0006464//cellular protein modification process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0060986;GO:0055065//metal ion homeostasis;GO:0006464//cellular protein modification process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway "gi|148681559|gb|EDL13506.1|/0/Eph receptor B6, isoform CRA_a, partial [Mus musculus]" 14119 10480 0.04 0.046666667 0.222392421 Up 0.095255557 Fbn2 fibrillin 2 K06825|1|0.0|4609|lcm:102349374|fibrillin 1 GO:0031012//extracellular matrix GO:0046872//metal ion binding;GO:0005198//structural molecule activity GO:0048705//skeletal system morphogenesis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030282//bone mineralization;GO:0035108//limb morphogenesis;GO:0001649//osteoblast differentiation gi|118136302|ref|NP_034311.2|/0/fibrillin-2 precursor [Mus musculus] 330324 3151 0.066666667 0.056666667 -0.234465254 Down 0.095255557 6430584L05Rik RIKEN cDNA 6430584L05 gene - - - - - 56069 692 0.083333333 0.07 -0.251538767 Down 0.095255557 Il17b interleukin 17B K05490|1|1e-78|294|mmu:56069|interleukin 17B GO:0044421 GO:0005102//receptor binding GO:0030595//leukocyte chemotaxis;GO:0006952//defense response;GO:0001819//positive regulation of cytokine production gi|537235386|gb|ERE85210.1|/2.4551e-83/interleukin-17B-like protein [Cricetulus griseus] 75495 690 0.083333333 0.07 -0.251538767 Down 0.095255557 Morn5 MORN repeat containing 5 K19755|1|2e-08|61.2|tru:101064816|radial spoke head protein 1 - - - gi|58037413|ref|NP_083585.1|/3.05101e-102/MORN repeat-containing protein 5 [Mus musculus] 667736 1390 0.043333333 0.036666667 -0.2410081 Down 0.095255557 Gm8787 predicted gene 8787 "K12491|1|4e-46|188|clv:102091913|Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3" - - - gi|150010641|ref|NP_001092780.1|/0/uncharacterized protein LOC667736 [Mus musculus] 353504 1280 0.086666667 0.073333333 -0.2410081 Down 0.095255557 Dio3os "deiodinase, iodothyronine type III, opposite strand" - - - - - 13612 5328 0.036666667 0.043333333 0.2410081 Up 0.095255557 Edil3 EGF-like repeats and discoidin I-like domains 3 K17253|1|2e-164|583|dre:558580|lactadherin GO:0031988//membrane-bounded vesicle;GO:0031988//membrane-bounded vesicle GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0005102//receptor binding GO:0010810//regulation of cell-substrate adhesion;GO:0032502//developmental process;GO:0010810//regulation of cell-substrate adhesion;GO:0032502//developmental process gi|83921564|ref|NP_001033076.1|/0/EGF-like repeat and discoidin I-like domain-containing protein 3 isoform a precursor [Mus musculus] 75276 3041.06 0.063333333 0.053333333 -0.247927513 Down 0.095255557 Ppp1r1c "protein phosphatase 1, regulatory (inhibitor) subunit 1C" K17549|1|3e-24|116|mmu:75276|protein phosphatase 1 regulatory subunit 1C GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424 - GO:1901992//positive regulation of mitotic cell cycle phase transition;GO:0016049//cell growth;GO:0044092//negative regulation of molecular function;GO:0007154//cell communication;GO:1901992//positive regulation of mitotic cell cycle phase transition;GO:0016049//cell growth;GO:0044092//negative regulation of molecular function;GO:0007154//cell communication;GO:1901992//positive regulation of mitotic cell cycle phase transition;GO:0016049//cell growth;GO:0044092//negative regulation of molecular function;GO:0007154//cell communication;GO:1901992//positive regulation of mitotic cell cycle phase transition;GO:0016049//cell growth;GO:0044092//negative regulation of molecular function;GO:0007154//cell communication;GO:1901992//positive regulation of mitotic cell cycle phase transition;GO:0016049//cell growth;GO:0044092//negative regulation of molecular function;GO:0007154//cell communication gi|595582350|ref|NP_001277673.1|/3.01654e-28/protein phosphatase 1 regulatory subunit 1C isoform c [Mus musculus] 18436 2441 0.08 0.093333333 0.222392421 Up 0.095255557 P2rx1 "purinergic receptor P2X, ligand-gated ion channel, 1" K05215|1|0.0|828|mmu:18436|P2X purinoceptor 1 - - - gi|158711719|ref|NP_032797.3|/0/P2X purinoceptor 1 [Mus musculus] 269954 3010 0.053333333 0.063333333 0.247927513 Up 0.095255557 Ttll13 "tubulin tyrosine ligase-like family, member 13" K16582|1|0.0|1489|mmu:269954|tubulin polyglutamylase TTLL6/13 [EC:6.-.-.-] - GO:0016881//acid-amino acid ligase activity;GO:0032550 GO:0036211//protein modification process gi|119392072|ref|NP_808433.2|/0/tubulin polyglutamylase TTLL13 [Mus musculus] 93892 2712 0.083333333 0.07 -0.251538767 Down 0.095255557 Pcdhb21 protocadherin beta 21 K16494|1|0.0|1370|mmu:93892|protocadherin beta - - - - 100039596 3766 0.08 0.093333333 0.222392421 Up 0.095255557 Tcf24 transcription factor 24 K09072|1|6e-11|61.6|lve:103078287|musculin (activated B-cell factor-1) - - - gi|549806786|ref|NP_001272354.1|/3.53593e-53/transcription factor 24 [Mus musculus] 72431 1952 0.08 0.093333333 0.222392421 Up 0.095255557 Ceacam18 carcinoembryonic antigen-related cell adhesion molecule 18 K06499|1|0.0|780|mmu:72431|carcinoembryonic antigen-related cell adhesion molecule GO:0031224//intrinsic component of membrane - - gi|58037299|ref|NP_082512.1|/0/carcinoembryonic antigen-related cell adhesion molecule 18 precursor [Mus musculus] 76649 586 0.093333333 0.08 -0.222392421 Down 0.095255557 1700119H24Rik RIKEN cDNA 1700119H24 gene - - - - "gi|148665452|gb|EDK97868.1|/2.44803e-47/mCG144812, partial [Mus musculus]" 320454 2872 0.073333333 0.086666667 0.2410081 Up 0.095255557 Tmprss11g "transmembrane protease, serine 11g" K18769|1|0.0|808|mmu:320454|transmembrane protease serine 11G [EC:3.4.21.-] GO:0016021//integral component of membrane GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|188536038|ref|NP_796136.2|/0/transmembrane protease serine 11G [Mus musculus] 100504164 1130 0.093333333 0.08 -0.222392421 Down 0.095255557 Cmtm1 CKLF-like MARVEL transmembrane domain containing 1 K17582|1|2e-16|89.0|xtr:779458|antigen KI-67 - - - gi|340545536|ref|NP_871790.2|/1.5637e-147/CKLF-like MARVEL transmembrane domain-containing protein 1 [Mus musculus] 19225 4460 0.09 0.076666667 -0.231325546 Down 0.095255557 Ptgs2 prostaglandin-endoperoxide synthase 2 K11987|1|0.0|1207|mmu:19225|prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1] - - - - 16878 4015 0.076666667 0.09 0.231325546 Up 0.095255557 Lif leukemia inhibitory factor K05419|1|2e-105|386|mmu:16878|leukemia inhibitory factor - - - - 244810 4293 0.046666667 0.04 -0.222392421 Down 0.095255557 AW551984 expressed sequence AW551984 K18466|1|5e-64|249|smm:Smp_073130.2|vacuolar protein sorting-associated protein 26;K10798|3|6e-63|246|aqu:100633591|poly [ADP-ribose] polymerase [EC:2.4.2.30] - - GO:0055007//cardiac muscle cell differentiation;GO:0055007//cardiac muscle cell differentiation "gi|148693542|gb|EDL25489.1|/0/expressed sequence AW551984, isoform CRA_a, partial [Mus musculus]" 224661 3674 0.043333333 0.036666667 -0.2410081 Down 0.095255557 Slc26a8 "solute carrier family 26, member 8" "K14705|1|0.0|1684|mmu:224661|solute carrier family 26 (testis anion transporter), member 8" - - - - 328263 3732 0.053333333 0.063333333 0.247927513 Up 0.095255557 A530065N20Rik RIKEN cDNA A530046M15 gene - - - - - 18386 4021 0.04 0.046666667 0.222392421 Up 0.095255557 Oprd1 "opioid receptor, delta 1" K04213|1|1e-161|573|mmu:18386|delta-type opioid receptor GO:0031224//intrinsic component of membrane;GO:0043226//organelle;GO:0033267;GO:0032589//neuron projection membrane;GO:0097060//synaptic membrane;GO:0044424 GO:0004985//opioid receptor activity GO:0006606//protein import into nucleus;GO:0070848//response to growth factor;GO:0019233//sensory perception of pain;GO:0007626//locomotory behavior;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0006816//calcium ion transport gi|124244064|ref|NP_038650.3|/9.35652e-161/delta-type opioid receptor [Mus musculus] 13389 2163 0.07 0.083333333 0.251538767 Up 0.095255557 Dll3 delta-like 3 (Drosophila) K06051|1|0.0|1092|mmu:13389|delta GO:0031224//intrinsic component of membrane GO:0005102//receptor binding GO:0007498//mesoderm development;GO:0045686//negative regulation of glial cell differentiation;GO:0009952//anterior/posterior pattern specification;GO:0043009//chordate embryonic development;GO:0010720//positive regulation of cell development;GO:0007219//Notch signaling pathway;GO:0045165//cell fate commitment gi|116292184|ref|NP_031892.2|/0/delta-like protein 3 precursor [Mus musculus] 18985 2566 0.08 0.093333333 0.222392421 Up 0.095255557 Pou2af1 "POU domain, class 2, associating factor 1" K14214|1|3e-28|129|cmk:103187707|NF-kappa-B inhibitor delta GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|6755128|ref|NP_035266.1|/4.79522e-136/POU domain class 2-associating factor 1 [Mus musculus] 230824 2798 0.093333333 0.08 -0.222392421 Down 0.095255557 Grhl3 grainyhead-like 3 (Drosophila) K09275|1|0.0|1208|mmu:230824|transcription factor CP2 and related proteins - - - - 242748 8689 0.043333333 0.036666667 -0.2410081 Down 0.095255557 Ptchd2 patched domain containing 2 K18730|1|7e-122|442|bfo:BRAFLDRAFT_118428|PERQ amino acid-rich with GYF domain-containing protein - - - gi|134053935|ref|NP_001076811.1|/0/patched domain-containing protein 2 [Mus musculus] 329278 5825 0.043333333 0.036666667 -0.2410081 Down 0.095255557 Tnn tenascin N K06252|1|0.0|3108|mmu:329278|tenascin GO:0031012//extracellular matrix;GO:0044464 GO:0005515//protein binding GO:0048870//cell motility;GO:0031589//cell-substrate adhesion;GO:0040007//growth;GO:0048667//cell morphogenesis involved in neuron differentiation gi|224922775|ref|NP_808507.2|/0/tenascin-N precursor [Mus musculus] 319819 3402 0.036666667 0.043333333 0.2410081 Up 0.095255557 4932435O22Rik RIKEN cDNA 4932435O22 gene - - - - gi|148702486|gb|EDL34433.1|/1.23534e-65/RIKEN cDNA 4932435O22 [Mus musculus] 108723 4112 0.056666667 0.066666667 0.234465254 Up 0.095255557 Card11 "caspase recruitment domain family, member 11" K07367|1|0.0|2109|mmu:108723|caspase recruitment domain-containing protein 11 GO:0044425;GO:0043235//receptor complex;GO:0044444//cytoplasmic part "GO:0019904//protein domain specific binding;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0030183//B cell differentiation;GO:0050851//antigen receptor-mediated signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0030888//regulation of B cell proliferation;GO:0042094//interleukin-2 biosynthetic process;GO:0031294//lymphocyte costimulation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0033077//T cell differentiation in thymus;GO:0042098//T cell proliferation gi|47847424|dbj|BAD21384.1|/0/mFLJ00120 protein [Mus musculus] 75040 693 0.083333333 0.07 -0.251538767 Down 0.095255557 Efcab10 EF-hand calcium binding domain 10 - - GO:0046872//metal ion binding;GO:0019887//protein kinase regulator activity GO:0007154//cell communication gi|242247071|ref|NP_083428.1|/1.54493e-69/EF-hand calcium-binding domain-containing protein 10 [Mus musculus] 56720 1646 0.07 0.06 -0.222392421 Down 0.095255557 Tdo2 "tryptophan 2,3-dioxygenase" "K00453|1|0.0|796|mmu:56720|tryptophan 2,3-dioxygenase [EC:1.13.11.11]" - "GO:0046906//tetrapyrrole binding;GO:0046914//transition metal ion binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0031406//carboxylic acid binding" GO:0006084//acetyl-CoA metabolic process;GO:0006569//tryptophan catabolic process "gi|31982697|ref|NP_064295.2|/0/tryptophan 2,3-dioxygenase [Mus musculus]" 258508 918 0.063333333 0.053333333 -0.247927513 Down 0.095255557 Olfr99 olfactory receptor 99 K04257|1|1e-149|531|mmu:258508|olfactory receptor GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007608//sensory perception of smell gi|33239262|ref|NP_666726.1|/1.00693e-148/olfactory receptor 99 [Mus musculus] 14528 2764 2.726666667 2.69 -0.01953217 Down 0.095001692 Gch1 GTP cyclohydrolase 1 K01495|1|6e-127|457|mmu:14528|GTP cyclohydrolase I [EC:3.5.4.16] GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0031982//vesicle;GO:0005635//nuclear envelope;GO:0044444//cytoplasmic part GO:0048037//cofactor binding;GO:0046914//transition metal ion binding;GO:0032550;GO:0003933//GTP cyclohydrolase activity;GO:0042802//identical protein binding GO:0033555//multicellular organismal response to stress;GO:0032770//positive regulation of monooxygenase activity;GO:0009396//folic acid-containing compound biosynthetic process;GO:0042417//dopamine metabolic process;GO:0051066//dihydrobiopterin metabolic process;GO:0034097//response to cytokine;GO:0051259//protein oligomerization;GO:0012502//induction of programmed cell death;GO:0009154//purine ribonucleotide catabolic process;GO:0002237//response to molecule of bacterial origin;GO:0050880//regulation of blood vessel size;GO:0008217//regulation of blood pressure;GO:0050905//neuromuscular process gi|6679967|ref|NP_032128.1|/4.90047e-126/GTP cyclohydrolase 1 precursor [Mus musculus] 193736 1835 3.02 3.056666667 0.017410684 Up 0.095001692 Zbtb12 zinc finger and BTB domain containing 12 K10499|1|0.0|679|mmu:193736|zinc finger and BTB domain-containing protein 12 - GO:0046872//metal ion binding - gi|767939465|ref|XP_011512685.1|/0/PREDICTED: zinc finger and BTB domain-containing protein 12 isoform X1 [Homo sapiens] 321007 5540 2.833333333 2.873333333 0.020225028 Up 0.095001692 Serac1 serine active site containing 1 - GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane GO:0016787//hydrolase activity;GO:0016787//hydrolase activity GO:0006644//phospholipid metabolic process;GO:0043062//extracellular structure organization;GO:0006664//glycolipid metabolic process;GO:0015031//protein transport;GO:0006644//phospholipid metabolic process;GO:0043062//extracellular structure organization;GO:0006664//glycolipid metabolic process;GO:0015031//protein transport gi|161169010|ref|NP_001104487.1|/0/protein SERAC1 isoform 3 [Mus musculus] 192654 2721 4.113333333 4.07 -0.015279194 Down 0.095001692 Pla2g15 "phospholipase A2, group XV" K06129|1|0.0|820|mmu:192654|lysophospholipase III [EC:3.1.1.5] GO:0000323//lytic vacuole "GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0008289//lipid binding;GO:0004623//phospholipase A2 activity" GO:0006631//fatty acid metabolic process;GO:0006650//glycerophospholipid metabolic process;GO:0006665//sphingolipid metabolic process gi|19527008|ref|NP_598553.1|/0/group XV phospholipase A2 precursor [Mus musculus] 268294 2751.6 3.253333333 3.216666667 -0.016352205 Down 0.095001692 Zbtb24 zinc finger and BTB domain containing 24 K10503|1|0.0|1415|mmu:268294|zinc finger and BTB domain-containing protein 24 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|31542230|ref|NP_700447.2|/0/zinc finger and BTB domain-containing protein 24 isoform 1 [Mus musculus] 18805 4962.87 2.77 2.81 0.020684154 Up 0.095001692 Pld1 phospholipase D1 K01115|1|0.0|2045|mmu:18805|phospholipase D1/2 [EC:3.1.4.4] GO:0005795//Golgi stack;GO:0031252//cell leading edge;GO:0005770//late endosome;GO:0031090//organelle membrane;GO:0012505//endomembrane system;GO:0005795//Golgi stack;GO:0031252//cell leading edge;GO:0005770//late endosome;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0004620//phospholipase activity;GO:0005543//phospholipid binding;GO:0004620//phospholipase activity;GO:0005543//phospholipid binding GO:0016477//cell migration;GO:0009725//response to hormone;GO:0042742//defense response to bacterium;GO:0046473//phosphatidic acid metabolic process;GO:0016477//cell migration;GO:0009725//response to hormone;GO:0042742//defense response to bacterium;GO:0046473//phosphatidic acid metabolic process gi|47059071|ref|NP_032901.2|/0/phospholipase D1 [Mus musculus] 98845 3079 2.14 2.103333333 -0.024933292 Down 0.095001692 Eps8l2 EPS8-like 2 K17277|1|0.0|1396|mmu:98845|epidermal growth factor receptor kinase substrate 8 GO:0044424 GO:0003779//actin binding GO:0007265//Ras protein signal transduction "gi|148686108|gb|EDL18055.1|/0/EPS8-like 2, isoform CRA_d, partial [Mus musculus]" 233789 15553 2.543333333 2.506666667 -0.020950395 Down 0.095001692 Smg1 "SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)" K08873|1|0.0|6653|mmu:233789|serine/threonine-protein kinase SMG1 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle "GO:0032550;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0050896//response to stimulus;GO:0006468//protein phosphorylation gi|73532758|ref|NP_001026984.1|/0/serine/threonine-protein kinase SMG1 [Mus musculus] 238247 5780 2.77 2.806666667 0.018971756 Up 0.095001692 Arid4a AT rich interactive domain 4A (RBP1-like) K19194|1|0.0|1877|mmu:238247|AT-rich interactive domain-containing protein 4A - - - gi|124487105|ref|NP_001074664.1|/0/AT-rich interactive domain-containing protein 4A [Mus musculus] 12916 2217.81 3.153333333 3.11 -0.019963102 Down 0.095001692 Crem cAMP responsive element modulator K09052|1|1e-102|376|fca:101094681|cAMP response element modulator GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006664//glycolipid metabolic process;GO:0048232//male gamete generation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030522//intracellular receptor signaling pathway;GO:0019318//hexose metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0007623//circadian rhythm;GO:0006664//glycolipid metabolic process;GO:0048232//male gamete generation;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0006366//transcription from RNA polymerase II promoter;GO:0030522//intracellular receptor signaling pathway;GO:0019318//hexose metabolic process;GO:0032787//monocarboxylic acid metabolic process;GO:0007623//circadian rhythm;GO:0006664//glycolipid metabolic process;GO:0048232//male gamete generation;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0006366//transcription from RNA polymerase II promoter;GO:0006664//glycolipid metabolic process;GO:0048232//male gamete generation;GO:0006366//transcription from RNA polymerase II promoter gi|408357979|ref|NP_001104324.2|/3.85897e-53/cAMP-responsive element modulator isoform 10 [Mus musculus] 71382 4507.52 2.24 2.203333333 -0.023810961 Down 0.095001692 Pex1 peroxisomal biogenesis factor 1 K13338|1|0.0|2320|mmu:71382|peroxin-1 GO:0031981//nuclear lumen;GO:0044439;GO:0031981//nuclear lumen;GO:0044439 GO:0032550;GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0032550;GO:0016887//ATPase activity;GO:0005515//protein binding GO:0006625//protein targeting to peroxisome;GO:0007017//microtubule-based process;GO:0006625//protein targeting to peroxisome;GO:0007017//microtubule-based process gi|61657895|ref|NP_082053.1|/0/peroxisome biogenesis factor 1 isoform 2 [Mus musculus] 65246 15118 4.183333333 4.14 -0.015022191 Down 0.095001692 Xpo7 exportin 7 K18460|1|0.0|2165|cjc:100389347|exportin-7 GO:0005635//nuclear envelope GO:0017016//Ras GTPase binding;GO:0022892//substrate-specific transporter activity GO:0050658//RNA transport;GO:0051169//nuclear transport;GO:0006886//intracellular protein transport gi|675714002|ref|XP_008977430.1|/0/PREDICTED: LOW QUALITY PROTEIN: exportin-7 [Callithrix jacchus] 22782 5230 3.673333333 3.633333333 -0.015796089 Down 0.095001692 Slc30a1 "solute carrier family 30 (zinc transporter), member 1" "K14688|1|0.0|813|mmu:22782|solute carrier family 30 (zinc transporter), member 1" GO:0042383//sarcolemma;GO:0031224//intrinsic component of membrane GO:0046915//transition metal ion transmembrane transporter activity;GO:0005246//calcium channel regulator activity GO:0015691//cadmium ion transport;GO:0072503;GO:0007269//neurotransmitter secretion;GO:0034766//negative regulation of ion transmembrane transport;GO:0071578//zinc II ion transmembrane import;GO:0009636//response to toxic substance;GO:0043009//chordate embryonic development;GO:0070588//calcium ion transmembrane transport;GO:0006875//cellular metal ion homeostasis gi|6678017|ref|NP_033605.1|/0/zinc transporter 1 [Mus musculus] 229780 3159 3.593333333 3.55 -0.017503748 Down 0.095001692 Trmt13 tRNA methyltransferase 13 K15446|1|0.0|989|mmu:229780|tRNA:m4X modification enzyme [EC:2.1.1.225] - GO:0016741;GO:0043169//cation binding GO:0006399//tRNA metabolic process gi|124430711|ref|NP_084292.1|/0/tRNA:m(4)X modification enzyme TRM13 homolog [Mus musculus] 320302 2737 3.37 3.333333333 -0.015782997 Down 0.095001692 Glt28d2 glycosyltransferase 28 domain containing 2 "K07432|1|6e-89|331|mmu:320302|beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141]" GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0008375//acetylglucosaminyltransferase activity GO:0030258//lipid modification;GO:0006487//protein N-linked glycosylation gi|260166652|ref|NP_796104.2|/5.23478e-88/glycosyltransferase 28 domain containing 1-like [Mus musculus] 52840 3706 4.073333333 4.116666667 0.015266757 Up 0.095001692 Dbndd2 dysbindin (dystrobrevin binding protein 1) domain containing 2 K20189|1|7e-16|89.4|cmy:102937626|dysbindin - - GO:0001933//negative regulation of protein phosphorylation;GO:0001933//negative regulation of protein phosphorylation;GO:0001933//negative regulation of protein phosphorylation;GO:0001933//negative regulation of protein phosphorylation "gi|148674447|gb|EDL06394.1|/4.70289e-47/dysbindin (dystrobrevin binding protein 1) domain containing 2, isoform CRA_d, partial [Mus musculus]" 101185 3153 3.24 3.196666667 -0.019425499 Down 0.095001692 Pot1a protection of telomeres 1A K11109|1|0.0|1269|mmu:101185|protection of telomeres protein 1 GO:0000782//telomere cap complex;GO:0043231//intracellular membrane-bounded organelle GO:0003697//single-stranded DNA binding;GO:0043565//sequence-specific DNA binding;GO:0019899//enzyme binding;GO:0004857//enzyme inhibitor activity GO:0051095;GO:0022616//DNA strand elongation;GO:0051348//negative regulation of transferase activity;GO:0051347//positive regulation of transferase activity;GO:0007004//telomere maintenance via telomerase;GO:0032392//DNA geometric change gi|19527150|ref|NP_598692.1|/0/protection of telomeres protein 1 [Mus musculus] 230161 5048 3.533333333 3.496666667 -0.015049587 Down 0.095001692 Acnat1 acyl-coenzyme A amino acid N-acyltransferase 1 K00659|1|3e-158|562|ocu:100350872|bile acid-CoA:amino acid N-acyltransferase [EC:2.3.1.65 3.1.2.2] GO:0042579//microbody "GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0016788//hydrolase activity, acting on ester bonds" GO:0006732;GO:0032787//monocarboxylic acid metabolic process;GO:0044238//primary metabolic process gi|257096024|ref|NP_001158037.1|/0/acyl-coenzyme A amino acid N-acyltransferase 1 [Mus musculus] 320150 4563 2.756666667 2.716666667 -0.02108727 Down 0.095001692 Zdhhc17 "zinc finger, DHHC domain containing 17" K20032|1|0.0|1291|lve:103082811|palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225] GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane GO:0046914//transition metal ion binding;GO:0060089;GO:0016409//palmitoyltransferase activity;GO:0046873//metal ion transmembrane transporter activity GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006497//protein lipidation;GO:0070838//divalent metal ion transport;GO:0015031//protein transport gi|817344043|ref|XP_012297503.1|/0/PREDICTED: palmitoyltransferase ZDHHC17 [Aotus nancymaae] 75316 1244.65 2.753333333 2.713333333 -0.021112987 Down 0.095001692 Taf1d "TATA-box binding protein associated factor, RNA polymerase I, D" K15215|1|8e-130|466|mmu:75316|TATA box-binding protein-associated factor RNA polymerase I subunit D GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148693075|gb|EDL25022.1|/1.45825e-131/mCG22663, isoform CRA_c, partial [Mus musculus]" 114674 3468 3.523333333 3.566666667 0.01763542 Up 0.095001692 Gtf2ird2 GTF2I repeat domain containing 2 K09228|1|4e-118|429|gja:107122456|KRAB domain-containing zinc finger protein;K03121|2|1e-104|384|oas:101113297|transcription initiation factor TFII-I GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|16716603|ref|NP_444496.1|/0/general transcription factor II-I repeat domain-containing protein 2 [Mus musculus] 54153 2842.56 3.433333333 3.393333333 -0.016906776 Down 0.095001692 Rasa4 RAS p21 protein activator 4 K17630|1|0.0|1558|mmu:54153|Ras GTPase-activating protein 4 - - - gi|84993718|ref|NP_001034192.1|/0/ras GTPase-activating protein 4 isoform 2 [Mus musculus] 75292 5295.24 3.04 3.076666667 0.017296823 Up 0.095001692 Prkd3 protein kinase D3 K06070|1|0.0|1632|mmu:75292|protein kinase D [EC:2.7.11.13] GO:0044424;GO:0044424;GO:0044424 GO:0043169//cation binding;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032550;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007165//signal transduction;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007165//signal transduction;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0007165//signal transduction "gi|148706531|gb|EDL38478.1|/0/protein kinase C, nu, isoform CRA_c, partial [Mus musculus]" 77579 7783 3.486666667 3.523333333 0.015092525 Up 0.095001692 Myh10 "myosin, heavy polypeptide 10, non-muscle" K10352|1|0.0|3245|mmu:77579|myosin heavy chain GO:0032432//actin filament bundle;GO:0032155;GO:0045202//synapse;GO:0030425//dendrite;GO:0016459//myosin complex;GO:0044444//cytoplasmic part;GO:0015630//microtubule cytoskeleton;GO:0044297//cell body;GO:0016020//membrane "GO:0042623//ATPase activity, coupled;GO:0032550;GO:0003774//motor activity;GO:0003779//actin binding" GO:0030239//myofibril assembly;GO:0043009//chordate embryonic development;GO:0007009//plasma membrane organization;GO:0021537//telencephalon development;GO:0009154//purine ribonucleotide catabolic process;GO:0021591//ventricular system development;GO:0006935//chemotaxis;GO:0040023//establishment of nucleus localization;GO:0043010//camera-type eye development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0021695//cerebellar cortex development;GO:0022604//regulation of cell morphogenesis;GO:0006929//substrate-dependent cell migration;GO:0016192//vesicle-mediated transport;GO:0050905//neuromuscular process;GO:0030030//cell projection organization gi|755540019|ref|XP_011247615.1|/0/PREDICTED: myosin-10 isoform X2 [Mus musculus] 66408 5567.69 2.87 2.833333333 -0.018550396 Down 0.095001692 Aptx aprataxin K10863|1|0.0|598|mmu:66408|aprataxin [EC:3.-.-.-] GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0031981//nuclear lumen;GO:0000785//chromatin GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0035312//5'-3' exodeoxyribonuclease activity;GO:0005515//protein binding;GO:0043566//structure-specific DNA binding;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0035312//5'-3' exodeoxyribonuclease activity;GO:0005515//protein binding;GO:0043566//structure-specific DNA binding;GO:0003723//RNA binding;GO:0046914//transition metal ion binding;GO:0035312//5'-3' exodeoxyribonuclease activity;GO:0005515//protein binding;GO:0043566//structure-specific DNA binding GO:0010608//posttranscriptional regulation of gene expression;GO:0006281//DNA repair;GO:0000302//response to reactive oxygen species;GO:0010608//posttranscriptional regulation of gene expression;GO:0006281//DNA repair;GO:0000302//response to reactive oxygen species;GO:0010608//posttranscriptional regulation of gene expression;GO:0006281//DNA repair;GO:0000302//response to reactive oxygen species gi|32526865|ref|NP_079821.3|/0/aprataxin isoform a [Mus musculus] 73852 3432.03 2.683333333 2.64 -0.023488353 Down 0.095001692 D3Ertd751e "DNA segment, Chr 3, ERATO Doi 751, expressed" - - - - "gi|148703230|gb|EDL35177.1|/1.98334e-114/DNA segment, Chr 3, ERATO Doi 751, expressed, isoform CRA_c [Mus musculus]" 244141 3770 2.92 2.956666667 0.018003235 Up 0.095001692 Nars2 asparaginyl-tRNA synthetase 2 (mitochondrial)(putative) K01893|1|0.0|929|mmu:244141|asparaginyl-tRNA synthetase [EC:6.1.1.22] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004812//aminoacyl-tRNA ligase activity GO:0006418//tRNA aminoacylation for protein translation "gi|157951696|ref|NP_705819.3|/0/probable asparagine--tRNA ligase, mitochondrial precursor [Mus musculus]" 16409 4679.99 2.376666667 2.34 -0.022431046 Down 0.095001692 Itgam integrin alpha M K06461|1|0.0|2232|mmu:16409|integrin alpha M GO:0043231//intracellular membrane-bounded organelle;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane GO:0043169//cation binding;GO:0043168//anion binding;GO:0046983//protein dimerization activity;GO:0005539//glycosaminoglycan binding;GO:0043169//cation binding;GO:0043168//anion binding;GO:0046983//protein dimerization activity;GO:0005539//glycosaminoglycan binding GO:0016337//single organismal cell-cell adhesion;GO:0014004//microglia differentiation;GO:0007166//cell surface receptor signaling pathway;GO:0042098//T cell proliferation;GO:0030595//leukocyte chemotaxis;GO:0016337//single organismal cell-cell adhesion;GO:0014004//microglia differentiation;GO:0007166//cell surface receptor signaling pathway;GO:0042098//T cell proliferation;GO:0030595//leukocyte chemotaxis gi|132626295|ref|NP_032427.2|/0/integrin alpha-M isoform 2 precursor [Mus musculus] 212627 1791.53 2.99 3.033333333 0.02075856 Up 0.095001692 Prpsap2 phosphoribosyl pyrophosphate synthetase-associated protein 2 K00948|1|3e-68|262|tad:TRIADDRAFT_25357|ribose-phosphate pyrophosphokinase [EC:2.7.6.1] GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex GO:0046872//metal ion binding;GO:0016778;GO:0046872//metal ion binding;GO:0016778;GO:0046872//metal ion binding;GO:0016778;GO:0046872//metal ion binding;GO:0016778 GO:0001501//skeletal system development;GO:0009117//nucleotide metabolic process;GO:0001501//skeletal system development;GO:0009117//nucleotide metabolic process;GO:0001501//skeletal system development;GO:0009117//nucleotide metabolic process;GO:0001501//skeletal system development;GO:0009117//nucleotide metabolic process gi|821012724|ref|XP_012356701.1|/1.48306e-180/PREDICTED: phosphoribosyl pyrophosphate synthase-associated protein 2 isoform X1 [Nomascus leucogenys] 56324 4124 4.043333333 4.086666667 0.015379429 Up 0.095001692 Stam2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 K04705|1|0.0|1014|mmu:56324|signal transducing adaptor molecule GO:0031981//nuclear lumen;GO:0005769//early endosome GO:0005488//binding GO:0044765//single-organism transport;GO:0015031//protein transport;GO:0007173//epidermal growth factor receptor signaling pathway gi|9789975|ref|NP_062641.1|/0/signal transducing adapter molecule 2 [Mus musculus] 72560 2690 2.91 2.953333333 0.021325045 Up 0.095001692 Naalad2 N-acetylated alpha-linked acidic dipeptidase 2 K01301|1|0.0|1501|mmu:72560|N-acetylated-alpha-linked acidic dipeptidase [EC:3.4.17.21] GO:0031224//intrinsic component of membrane "GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0043169//cation binding;GO:0008238//exopeptidase activity" GO:0019538//protein metabolic process;GO:0042133//neurotransmitter metabolic process "gi|148693094|gb|EDL25041.1|/0/N-acetylated alpha-linked acidic dipeptidase 2, isoform CRA_a [Mus musculus]" 12505 4409 2.953333333 2.913333333 -0.019673419 Down 0.095001692 Cd44 CD44 antigen K06256|1|0.0|684|cge:100750640|CD44 antigen GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0009986//cell surface;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0044459 GO:0005539//glycosaminoglycan binding;GO:0019900//kinase binding;GO:0038023//signaling receptor activity;GO:0015929//hexosaminidase activity;GO:0070851//growth factor receptor binding;GO:0005539//glycosaminoglycan binding;GO:0019900//kinase binding;GO:0038023//signaling receptor activity;GO:0015929//hexosaminidase activity;GO:0070851//growth factor receptor binding;GO:0005539//glycosaminoglycan binding;GO:0019900//kinase binding;GO:0038023//signaling receptor activity;GO:0015929//hexosaminidase activity;GO:0070851//growth factor receptor binding;GO:0005539//glycosaminoglycan binding;GO:0019900//kinase binding;GO:0038023//signaling receptor activity;GO:0015929//hexosaminidase activity;GO:0070851//growth factor receptor binding "GO:0010467//gene expression;GO:0006954//inflammatory response;GO:0070486//leukocyte aggregation;GO:0002901;GO:0001501//skeletal system development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006027//glycosaminoglycan catabolic process;GO:0048870//cell motility;GO:0043410//positive regulation of MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0000768//syncytium formation by plasma membrane fusion;GO:0007166//cell surface receptor signaling pathway;GO:0001781//neutrophil apoptotic process;GO:0071363//cellular response to growth factor stimulus;GO:0034112//positive regulation of homotypic cell-cell adhesion;GO:0033273//response to vitamin;GO:0060740//prostate gland epithelium morphogenesis;GO:0001568//blood vessel development;GO:0030030//cell projection organization;GO:0010467//gene expression;GO:0006954//inflammatory response;GO:0070486//leukocyte aggregation;GO:0002901;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006027//glycosaminoglycan catabolic process;GO:0048870//cell motility;GO:0002250//adaptive immune response;GO:0043410//positive regulation of MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0000768//syncytium formation by plasma membrane fusion;GO:0007166//cell surface receptor signaling pathway;GO:0001781//neutrophil apoptotic process;GO:0071363//cellular response to growth factor stimulus;GO:0034112//positive regulation of homotypic cell-cell adhesion;GO:0060740//prostate gland epithelium morphogenesis;GO:0030030//cell projection organization;GO:0010467//gene expression;GO:0006954//inflammatory response;GO:0070486//leukocyte aggregation;GO:0002901;GO:0001501//skeletal system development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006027//glycosaminoglycan catabolic process;GO:0048870//cell motility;GO:0002250//adaptive immune response;GO:0043410//positive regulation of MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0000768//syncytium formation by plasma membrane fusion;GO:0007166//cell surface receptor signaling pathway;GO:0001781//neutrophil apoptotic process;GO:0071363//cellular response to growth factor stimulus;GO:0034112//positive regulation of homotypic cell-cell adhesion;GO:0033273//response to vitamin;GO:0060740//prostate gland epithelium morphogenesis;GO:0001568//blood vessel development;GO:0030030//cell projection organization;GO:0010467//gene expression;GO:0006954//inflammatory response;GO:0070486//leukocyte aggregation;GO:0002901;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006027//glycosaminoglycan catabolic process;GO:0048870//cell motility;GO:0002250//adaptive immune response;GO:0043410//positive regulation of MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0000768//syncytium formation by plasma membrane fusion;GO:0007166//cell surface receptor signaling pathway;GO:0001781//neutrophil apoptotic process;GO:0071363//cellular response to growth factor stimulus;GO:0034112//positive regulation of homotypic cell-cell adhesion;GO:0060740//prostate gland epithelium morphogenesis;GO:0030030//cell projection organization" gi|85540471|ref|NP_033981.2|/0/CD44 antigen isoform a precursor [Mus musculus] 234344 2990 2.9 2.856666667 -0.021720197 Down 0.095001692 Naf1 nuclear assembly factor 1 ribonucleoprotein K14763|1|0.0|655|mmu:234344|H/ACA ribonucleoprotein complex non-core subunit NAF1 GO:0005815//microtubule organizing center;GO:0030529//intracellular ribonucleoprotein complex GO:0003723//RNA binding GO:0042254//ribosome biogenesis;GO:0016070//RNA metabolic process gi|254675189|ref|NP_001157036.1|/0/H/ACA ribonucleoprotein complex non-core subunit NAF1 [Mus musculus] 100043468 3236 3.973333333 4.016666667 0.015648911 Up 0.095001692 Zfp955b zinc finger protein 955B K09228|1|3e-175|613|ngi:103736473|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - "gi|219279780|ref|NP_001136429.1|/0/zinc finger protein 422, related sequence 1-like [Mus musculus]" 235431 3626 14.78666667 14.70666667 -0.007826575 Down 0.09479484 Coro2b "coronin, actin binding protein, 2B" K13887|1|0.0|983|mmu:235431|coronin-2 - - - gi|148528987|ref|NP_780693.2|/0/coronin-2B [Mus musculus] 15505 3478 13.36666667 13.29 -0.008298631 Down 0.09479484 Hsph1 heat shock 105kDa/110kDa protein 1 K09485|1|0.0|1636|mmu:15505|heat shock protein 110kDa - - - - 93706 4687 11.54333333 11.46333333 -0.010033272 Down 0.09479484 Pcdhgc3 "protocadherin gamma subfamily C, 3" K16497|1|0.0|1765|mmu:93706|protocadherin gamma subfamily C GO:0031224//intrinsic component of membrane;GO:0030054//cell junction GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion "gi|18087747|ref|NP_291059.1|/0/protocadherin gamma subfamily C, 3 precursor [Mus musculus]" 56508 4109.06 9.013333333 9.093333333 0.012748493 Up 0.09479484 Rapgef4 Rap guanine nucleotide exchange factor (GEF) 4 K04351|1|6e-95|352|shr:100933298|Rap guanine nucleotide exchange factor 4 GO:0031513//nonmotile primary cilium;GO:0030425//dendrite;GO:0043234//protein complex;GO:0044459;GO:0044444//cytoplasmic part;GO:0045202//synapse;GO:0031513//nonmotile primary cilium;GO:0030425//dendrite;GO:0043234//protein complex;GO:0044459;GO:0044444//cytoplasmic part;GO:0045202//synapse;GO:0031513//nonmotile primary cilium;GO:0030425//dendrite;GO:0043234//protein complex;GO:0044459;GO:0044444//cytoplasmic part;GO:0045202//synapse;GO:0031513//nonmotile primary cilium;GO:0030425//dendrite;GO:0043234//protein complex;GO:0044459;GO:0044444//cytoplasmic part;GO:0045202//synapse GO:0031267//small GTPase binding;GO:0030551//cyclic nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0031267//small GTPase binding;GO:0030551//cyclic nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0031267//small GTPase binding;GO:0030551//cyclic nucleotide binding;GO:0019887//protein kinase regulator activity;GO:0031267//small GTPase binding;GO:0030551//cyclic nucleotide binding;GO:0019887//protein kinase regulator activity GO:0014909//smooth muscle cell migration;GO:0010975//regulation of neuron projection development;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0006887//exocytosis;GO:0007264//small GTPase mediated signal transduction;GO:0006468//protein phosphorylation;GO:0030072//peptide hormone secretion;GO:0007268//chemical synaptic transmission;GO:0019222//regulation of metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0015980//energy derivation by oxidation of organic compounds;GO:0007599//hemostasis;GO:0014909//smooth muscle cell migration;GO:0010975//regulation of neuron projection development;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0006887//exocytosis;GO:0007264//small GTPase mediated signal transduction;GO:0006468//protein phosphorylation;GO:0030073//insulin secretion;GO:0007268//chemical synaptic transmission;GO:0019222//regulation of metabolic process;GO:0001775//cell activation;GO:0014909//smooth muscle cell migration;GO:0010975//regulation of neuron projection development;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0006887//exocytosis;GO:0007264//small GTPase mediated signal transduction;GO:0006468//protein phosphorylation;GO:0030072//peptide hormone secretion;GO:0007268//chemical synaptic transmission;GO:0019222//regulation of metabolic process;GO:0014909//smooth muscle cell migration;GO:0010975//regulation of neuron projection development;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0006887//exocytosis;GO:0007264//small GTPase mediated signal transduction;GO:0006468//protein phosphorylation;GO:0030072//peptide hormone secretion;GO:0007268//chemical synaptic transmission;GO:0019222//regulation of metabolic process gi|60359974|dbj|BAD90206.1|/0/mKIAA4040 protein [Mus musculus] 107358 6144 11.00666667 11.08666667 0.010448048 Up 0.09479484 Tm9sf3 transmembrane 9 superfamily member 3 K17087|1|0.0|1082|rno:309475|transmembrane 9 superfamily member 3 GO:0031224//intrinsic component of membrane - - gi|60359970|dbj|BAD90204.1|/0/mKIAA4036 protein [Mus musculus] 77938 5164.44 8.4 8.48 0.013674937 Up 0.09479484 Fam53b "family with sequence similarity 53, member B" - - - - gi|31542068|ref|NP_780477.2|/0/protein FAM53B [Mus musculus] 18739 4242.4 10.05333333 9.976666667 -0.01104415 Down 0.09479484 Pitpnm1 "phosphatidylinositol transfer protein, membrane-associated 1" K00469|1|5e-12|77.0|pss:102444630|inositol oxygenase [EC:1.13.99.1];K16545|2|8e-12|76.3|lcm:102359704|phospholipase DDHD2 [EC:3.1.1.-] GO:0000139//Golgi membrane;GO:0032155;GO:0000139//Golgi membrane;GO:0032155 GO:0043169//cation binding;GO:0043169//cation binding GO:0045184//establishment of protein localization;GO:0045184//establishment of protein localization gi|6679339|ref|NP_032877.1|/0/membrane-associated phosphatidylinositol transfer protein 1 [Mus musculus] 68493 3632 12.46333333 12.38666667 -0.008901969 Down 0.09479484 Ndufaf4 "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4" K18161|1|4e-93|345|mmu:68493|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 GO:0005740//mitochondrial envelope GO:0005515//protein binding GO:0010257//NADH dehydrogenase complex assembly;GO:0008283//cell proliferation;GO:0006915//apoptotic process gi|21624617|ref|NP_081018.1|/3.70642e-92/NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 [Mus musculus] 15587 1872 20.30666667 20.22666667 -0.005694856 Down 0.09479484 Hyal2 hyaluronoglucosaminidase 2 K01197|1|0.0|998|mmu:15587|hyaluronoglucosaminidase [EC:3.2.1.35] "GO:0000323//lytic vacuole;GO:0046658//anchored component of plasma membrane;GO:0012505//endomembrane system;GO:0042995//cell projection;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0005102//receptor binding;GO:0004872//receptor activity;GO:0005539//glycosaminoglycan binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0015929//hexosaminidase activity;GO:0019838//growth factor binding;GO:0030292//protein tyrosine kinase inhibitor activity GO:0006954//inflammatory response;GO:0009636//response to toxic substance;GO:0030097//hemopoiesis;GO:0070555//response to interleukin-1;GO:0006915//apoptotic process;GO:0043405//regulation of MAP kinase activity;GO:0048871//multicellular organismal homeostasis;GO:0001501//skeletal system development;GO:0035809;GO:0006027//glycosaminoglycan catabolic process;GO:0010761//fibroblast migration;GO:0016049//cell growth;GO:0032675//regulation of interleukin-6 production;GO:0002274;GO:0006979//response to oxidative stress;GO:0010224//response to UV-B;GO:0006469//negative regulation of protein kinase activity;GO:0006606//protein import into nucleus;GO:0050715//positive regulation of cytokine secretion;GO:0002252;GO:0006366//transcription from RNA polymerase II promoter;GO:0071363//cellular response to growth factor stimulus;GO:0046718//viral entry into host cell;GO:0051707//response to other organism;GO:0034612//response to tumor necrosis factor;GO:0003097//renal water transport gi|45331202|ref|NP_034619.2|/0/hyaluronidase-2 precursor [Mus musculus] 67889 2549.83 12.74333333 12.82666667 0.009403599 Up 0.09479484 Rbm18 RNA binding motif protein 18 - - GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding;GO:0036094//small molecule binding;GO:0003676//nucleic acid binding - gi|227500539|ref|NP_001153107.1|/1.26397e-85/probable RNA-binding protein 18 isoform 2 [Mus musculus] 67495 2864 13.23666667 13.16 -0.008380371 Down 0.09479484 Tmem167b transmembrane protein 167B K09532|1|1e-11|75.1|cbr:CBG03468|DnaJ homolog subfamily C member 12 GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|190360731|ref|NP_001121975.1|/2.69263e-34/protein kish-B precursor [Bos taurus] 17342 4797.91 9.733333333 9.816666667 0.012299265 Up 0.09479484 Mitf microphthalmia-associated transcription factor K09455|1|0.0|765|mmu:17342|microphthalmia-associated transcription factor GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle "GO:0005515//protein binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0003676//nucleic acid binding" GO:0007166//cell surface receptor signaling pathway;GO:0048771//tissue remodeling;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0001654//eye development;GO:0065003;GO:0050931//pigment cell differentiation;GO:0002761//regulation of myeloid leukocyte differentiation;GO:0007166//cell surface receptor signaling pathway;GO:0048771//tissue remodeling;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0001654//eye development;GO:0065003;GO:0050931//pigment cell differentiation;GO:0002761//regulation of myeloid leukocyte differentiation gi|163965354|ref|NP_001106669.1|/0/microphthalmia-associated transcription factor isoform 1 [Mus musculus] 21981 4355 17.52666667 17.60333333 0.006296999 Up 0.09479484 Ppp1r13b "protein phosphatase 1, regulatory (inhibitor) subunit 13B" K17554|1|0.0|1969|mmu:21981|apoptosis-stimulating of p53 protein 1 GO:0044424 - GO:0012502//induction of programmed cell death gi|45592936|ref|NP_035755.1|/0/apoptosis-stimulating of p53 protein 1 [Mus musculus] 75751 3611 20.89666667 20.97666667 0.005512613 Up 0.09479484 Ipo4 importin 4 K20221|1|0.0|1767|mmu:75751|importin-4 GO:0005635//nuclear envelope GO:0022892//substrate-specific transporter activity GO:0015031//protein transport gi|19745156|ref|NP_077229.4|/0/importin-4 [Mus musculus] 12913 1582 17.23666667 17.32 0.006958126 Up 0.09479484 Creb3 cAMP responsive element binding protein 3 K09048|1|4e-172|607|mmu:12913|cyclic AMP-responsive element-binding protein 3 GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0044451;GO:0044297//cell body GO:0001071//nucleic acid binding transcription factor activity;GO:0048020//CCR chemokine receptor binding;GO:0003713//transcription coactivator activity;GO:0042802//identical protein binding;GO:0000976//transcription regulatory region sequence-specific DNA binding GO:0050691//regulation of defense response to virus by host;GO:0016049//cell growth;GO:0019042;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0044092//negative regulation of molecular function;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006816//calcium ion transport;GO:0050927//positive regulation of positive chemotaxis;GO:0051345//positive regulation of hydrolase activity gi|12805263|gb|AAH02094.1|/3.26345e-171/CAMP responsive element binding protein 3 [Mus musculus] 227526 3013 9.033333333 8.956666667 -0.01229653 Down 0.09479484 Cdnf cerebral dopamine neurotrophic factor K13190|1|6e-50|202|fca:101090926|RNA-binding protein 15 - GO:0005102//receptor binding - "gi|148675989|gb|EDL07936.1|/3.89542e-116/arginine-rich, mutated in early stage tumors-like 1, partial [Mus musculus]" 70796 2054 14.88333333 14.96666667 0.00805527 Up 0.09479484 Zdhhc1 "zinc finger, DHHC domain containing 1" K20027|1|0.0|737|mmu:70796|palmitoyltransferase ZDHHC1/11 [EC:2.3.1.225] GO:0016020//membrane "GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0046872//metal ion binding" GO:0006497//protein lipidation "gi|148679336|gb|EDL11283.1|/0/zinc finger, DHHC domain containing 1, isoform CRA_a, partial [Mus musculus]" 26374 5056 14.55333333 14.63 0.00758014 Up 0.09479484 Rfwd2 ring finger and WD repeat domain 2 K10143|1|0.0|1246|mmu:26374|E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003824//catalytic activity - gi|26024211|ref|NP_036061.1|/0/E3 ubiquitin-protein ligase RFWD2 [Mus musculus] 320808 5707 9.423333333 9.506666667 0.012702099 Up 0.09479484 Dcaf5 DDB1 and CUL4 associated factor 5 K11800|1|0.0|1690|mmu:320808|WD repeat-containing protein 22 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle - - "gi|148670715|gb|EDL02662.1|/0/WD repeat domain 22, isoform CRA_b, partial [Mus musculus]" 67983 1615 10.65666667 10.73333333 0.010341944 Up 0.09479484 Pdzd9 PDZ domain containing 9 - - - - gi|92373388|ref|NP_001035226.1|/4.29867e-134/PDZ domain-containing protein 9 isoform 1 [Mus musculus] 279029 2198 0.05 0.043333333 -0.206450877 Down 0.094503366 Stkld1 serine/threonine kinase-like domain containing 1 K17546|1|0.0|1220|mmu:279029|probable inactive protein kinase-like protein SgK071 - - - "gi|148676401|gb|EDL08348.1|/0/gene model 711, (NCBI), isoform CRA_b, partial [Mus musculus]" 242915 3832 0.053333333 0.046666667 -0.192645078 Down 0.094503366 Gareml "GRB2 associated, regulator of MAPK1-like" - - - - gi|268832229|ref|NP_001161351.1|/0/GRB2-associated and regulator of MAPK protein 2 [Mus musculus] 109342 2261 0.07 0.08 0.192645078 Up 0.094503366 Slc5a10 "solute carrier family 5 (sodium/glucose cotransporter), member 10" "K14390|1|0.0|977|mmu:109342|solute carrier family 5 (sodium/glucose cotransporter), member 10" GO:0031224//intrinsic component of membrane - GO:0030001//metal ion transport;GO:0044763 gi|84794617|ref|NP_001028399.1|/0/sodium/glucose cotransporter 5 [Mus musculus] 170788 4702 0.083333333 0.096666667 0.214124805 Up 0.094503366 Crb1 "crumbs family member 1, photoreceptor morphogenesis associated" K16681|1|0.0|3028|mmu:170788|protein crumbs - - - - 217845 1093 0.053333333 0.046666667 -0.192645078 Down 0.094503366 Ifi27l2b "interferon, alpha-inducible protein 27 like 2B" - - - - gi|21703896|ref|NP_663424.1|/2.07071e-32/interferon alpha-inducible protein 27-like protein 2B precursor [Mus musculus] 67753 1164 0.043333333 0.05 0.206450877 Up 0.094503366 Eqtn "equatorin, sperm acrosome associated" K19920|1|2e-163|577|mmu:67753|equatorin GO:0002080//acrosomal membrane;GO:0031224//intrinsic component of membrane;GO:0005768//endosome;GO:0002080//acrosomal membrane;GO:0031224//intrinsic component of membrane;GO:0005768//endosome GO:0005488//binding;GO:0005488//binding GO:0007340//acrosome reaction;GO:0007340//acrosome reaction gi|594591524|ref|NP_001277552.1|/2.77426e-147/equatorin isoform 2 precursor [Mus musculus] 12404 2345 0.086666667 0.1 0.206450877 Up 0.094503366 Cbln1 cerebellin 1 precursor protein K18744|1|1e-19|101|cjc:100398860|caprin-2 - GO:0042802//identical protein binding GO:0007416//synapse assembly;GO:0007267//cell-cell signaling;GO:0015031//protein transport gi|617555739|ref|XP_007538640.1|/6.71103e-105/PREDICTED: cerebellin-1 [Erinaceus europaeus] 11864 6073 0.08 0.07 -0.192645078 Down 0.094503366 Arnt2 aryl hydrocarbon receptor nuclear translocator 2 K15589|1|0.0|1226|mmu:11864|aryl hydrocarbon receptor nuclear translocator 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005102//receptor binding;GO:0060089;GO:0001071//nucleic acid binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003676//nucleic acid binding GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0043009//chordate embryonic development;GO:0007154//cell communication;GO:0006950//response to stress;GO:0007399//nervous system development gi|459215027|ref|NP_031514.3|/0/aryl hydrocarbon receptor nuclear translocator 2 [Mus musculus] 18212 7049 0.066666667 0.076666667 0.201633861 Up 0.094503366 Ntrk2 "neurotrophic tyrosine kinase, receptor, type 2" K04360|1|0.0|924|mmu:18212|neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1] GO:0031090//organelle membrane;GO:0033267;GO:0043231//intracellular membrane-bounded organelle;GO:0044327//dendritic spine head;GO:0016021//integral component of membrane;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0031090//organelle membrane;GO:0033267;GO:0043231//intracellular membrane-bounded organelle;GO:0044327//dendritic spine head;GO:0016021//integral component of membrane;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0031090//organelle membrane;GO:0033267;GO:0043231//intracellular membrane-bounded organelle;GO:0044327//dendritic spine head;GO:0016021//integral component of membrane;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0097060//synaptic membrane GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0032550;GO:0043121//neurotrophin binding;GO:0042802//identical protein binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0032550;GO:0043121//neurotrophin binding;GO:0042802//identical protein binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005102//receptor binding;GO:0032550;GO:0043121//neurotrophin binding;GO:0042802//identical protein binding "GO:0010467//gene expression;GO:0048167//regulation of synaptic plasticity;GO:0009612//response to mechanical stimulus;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0021543//pallium development;GO:0007613//memory;GO:0009967//positive regulation of signal transduction;GO:0045762//positive regulation of adenylate cyclase activity;GO:0035249//synaptic transmission, glutamatergic;GO:0016477//cell migration;GO:0007409//axonogenesis;GO:0010975//regulation of neuron projection development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048741//skeletal muscle fiber development;GO:0021953//central nervous system neuron differentiation;GO:0042462//eye photoreceptor cell development;GO:0008283//cell proliferation;GO:0019722//calcium-mediated signaling;GO:0006835//dicarboxylic acid transport;GO:0043066//negative regulation of apoptotic process;GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0007269//neurotransmitter secretion;GO:0010467//gene expression;GO:0048167//regulation of synaptic plasticity;GO:0009612//response to mechanical stimulus;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0021543//pallium development;GO:0007613//memory;GO:0009967//positive regulation of signal transduction;GO:0035249//synaptic transmission, glutamatergic;GO:0016477//cell migration;GO:0007409//axonogenesis;GO:0010975//regulation of neuron projection development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048741//skeletal muscle fiber development;GO:0021953//central nervous system neuron differentiation;GO:0042462//eye photoreceptor cell development;GO:0008283//cell proliferation;GO:0019722//calcium-mediated signaling;GO:0006835//dicarboxylic acid transport;GO:0043066//negative regulation of apoptotic process;GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0007269//neurotransmitter secretion;GO:0010467//gene expression;GO:0048167//regulation of synaptic plasticity;GO:0009612//response to mechanical stimulus;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0021543//pallium development;GO:0007613//memory;GO:0009967//positive regulation of signal transduction;GO:0045762//positive regulation of adenylate cyclase activity;GO:0035249//synaptic transmission, glutamatergic;GO:0016477//cell migration;GO:0007409//axonogenesis;GO:0010975//regulation of neuron projection development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0048741//skeletal muscle fiber development;GO:0021953//central nervous system neuron differentiation;GO:0042462//eye photoreceptor cell development;GO:0008283//cell proliferation;GO:0019722//calcium-mediated signaling;GO:0006835//dicarboxylic acid transport;GO:0043066//negative regulation of apoptotic process;GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0007269//neurotransmitter secretion" gi|68215970|ref|NP_001020245.1|/0/BDNF/NT-3 growth factors receptor isoform a precursor [Mus musculus] 328829 3583 0.043333333 0.05 0.206450877 Up 0.094503366 9830107B12Rik RIKEN cDNA 9830107B12 gene K06742|1|6e-19|91.3|cge:100771904|natural cytotoxicity triggering receptor 2;K14364|5|3e-13|80.9|fca:101090615|trem-like transcript 2 protein - - - - 320214 2765 0.053333333 0.046666667 -0.192645078 Down 0.094503366 Maats1 "MYCBP-associated, testis expressed 1" - - - - "gi|148665557|gb|EDK97973.1|/0/mCG129098, isoform CRA_b, partial [Mus musculus]" 18101 1173 0.05 0.043333333 -0.206450877 Down 0.094503366 Nmbr neuromedin B receptor K04168|1|0.0|765|mmu:18101|neuromedin B receptor GO:0016021//integral component of membrane;GO:0044424 GO:0008188//neuropeptide receptor activity GO:0007186//G-protein coupled receptor signaling pathway gi|6679076|ref|NP_032729.1|/0/neuromedin-B receptor [Mus musculus] 69941 713 0.076666667 0.066666667 -0.201633861 Down 0.094503366 2810408I11Rik RIKEN cDNA 2810408I11 gene - - - - "gi|564311715|ref|XP_006226931.1|/2.27665e-18/PREDICTED: cyclin-Y-like protein 1 isoform X1, partial [Rattus norvegicus]" 242667 3900 0.09 0.103333333 0.199308808 Up 0.094503366 Dlgap3 "discs, large (Drosophila) homolog-associated protein 3" "K15008|1|5e-127|458|gja:107118007|discs, large-associated protein 1" GO:0044456;GO:0044297//cell body;GO:0043197//dendritic spine;GO:0008328//ionotropic glutamate receptor complex;GO:0044456;GO:0044297//cell body;GO:0043197//dendritic spine;GO:0008328//ionotropic glutamate receptor complex GO:0042277//peptide binding;GO:0019904//protein domain specific binding;GO:0042277//peptide binding;GO:0019904//protein domain specific binding GO:0065003;GO:0065003 gi|443906724|ref|NP_775161.2|/0/disks large-associated protein 3 isoform 1 [Rattus norvegicus] 15043 2178 0.093333333 0.106666667 0.192645078 Up 0.094503366 H2-T3 "histocompatibility 2, T region locus 3" "K06751|1|0.0|776|mmu:15043|major histocompatibility complex, class I" - - - "gi|242332523|ref|NP_032234.3|/0/H-2 class I histocompatibility antigen, TLA(B) alpha chain precursor [Mus musculus]" 171170 8582 0.09 0.103333333 0.199308808 Up 0.094503366 Mbnl3 muscleblind-like 3 (Drosophila) K14943|1|0.0|684|mmu:171170|muscleblind GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0008380//RNA splicing;GO:0045445//myoblast differentiation;GO:0008380//RNA splicing;GO:0045445//myoblast differentiation gi|569009184|ref|XP_006541502.1|/3.70214e-157/PREDICTED: muscleblind-like protein 3 isoform X4 [Mus musculus] 328657 982 0.11 0.096666667 -0.186413124 Down 0.094503366 Gm1968 predicted gene 1968 - - - - - 320557 4537 0.1 0.086666667 -0.206450877 Down 0.094503366 Fam169a "family with sequence similarity 169, member A" K12869|1|1e-51|208|gfr:102042741|crooked neck GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|50510687|dbj|BAD32329.1|/0/mKIAA0888 protein [Mus musculus] 242800 3218 0.063333333 0.073333333 0.211504105 Up 0.094503366 Ttc34 tetratricopeptide repeat domain 34 - - - - gi|568931236|ref|XP_006538925.1|/0/PREDICTED: tetratricopeptide repeat protein 34 isoform X1 [Mus musculus] 73456 1493 0.106666667 0.093333333 -0.192645078 Down 0.094503366 Izumo1 izumo sperm-egg fusion 1 - GO:0001669//acrosomal vesicle;GO:0031224//intrinsic component of membrane GO:0042802//identical protein binding GO:0022610;GO:0007338//single fertilization gi|568948568|ref|XP_006541285.1|/0/PREDICTED: izumo sperm-egg fusion protein 1 isoform X1 [Mus musculus] 71436 3984 0.053333333 0.046666667 -0.192645078 Down 0.094503366 Flrt3 fibronectin leucine rich transmembrane protein 3 K16362|1|0.0|1217|mmu:71436|leucine-rich repeat transmembrane protein FLRT GO:0016021//integral component of membrane;GO:0031012//extracellular matrix;GO:0016021//integral component of membrane;GO:0031012//extracellular matrix GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0005515//protein binding - gi|37360402|dbj|BAC98179.1|/0/mKIAA1469 protein [Mus musculus] 625018 5369 0.063333333 0.073333333 0.211504105 Up 0.094503366 C4a complement component 4A (Rodgers blood group) K03989|1|0.0|3205|mmu:12268|complement component 4 GO:0044421 - GO:0019724//B cell mediated immunity gi|126215532|ref|NP_035543.2|/0/sex-limited protein precursor [Mus musculus] 433215 569 0.096666667 0.083333333 -0.214124805 Down 0.094503366 BC048609 transmembrane protein 262 - - - - gi|162417998|ref|NP_001104787.1|/5.52431e-62/transmembrane protein 262 [Mus musculus] 12189 6648 0.073333333 0.063333333 -0.211504105 Down 0.094503366 Brca1 "breast cancer 1, early onset" K10605|1|0.0|3555|mmu:12189|breast cancer type 1 susceptibility protein [EC:2.3.2.27] GO:0000931//gamma-tubulin large complex;GO:0031252//cell leading edge;GO:0005884//actin filament;GO:0000228//nuclear chromosome;GO:0044429;GO:0000152//nuclear ubiquitin ligase complex;GO:0016020//membrane;GO:0005924//cell-substrate adherens junction GO:0019787//ubiquitin-like protein transferase activity;GO:0008092//cytoskeletal protein binding;GO:0000975//regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0044389//ubiquitin-like protein ligase binding "GO:0006633//fatty acid biosynthetic process;GO:0071407//cellular response to organic cyclic compound;GO:0006915//apoptotic process;GO:0006281//DNA repair;GO:0006306//DNA methylation;GO:0031061//negative regulation of histone methylation;GO:0031667//response to nutrient levels;GO:0009314//response to radiation;GO:0007549//dosage compensation;GO:0000904//cell morphogenesis involved in differentiation;GO:0040012//regulation of locomotion;GO:0035066//positive regulation of histone acetylation;GO:0000077//DNA damage checkpoint;GO:0031062//positive regulation of histone methylation;GO:0006383//transcription from RNA polymerase III promoter;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0009792//embryo development ending in birth or egg hatching;GO:0007050//cell cycle arrest;GO:0043627//response to estrogen;GO:0007417//central nervous system development;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007099//centriole replication;GO:0000209//protein polyubiquitination;GO:0043984//histone H4-K16 acetylation" gi|161016835|ref|NP_033894.3|/0/breast cancer type 1 susceptibility protein homolog [Mus musculus] 231858 3727 0.723333333 0.7 -0.047305715 Down 0.094268306 Radil Ras association and DIL domains K14376|1|1e-166|590|myb:102258567|poly(A) polymerase [EC:2.7.7.19] - - GO:0022610;GO:0007154//cell communication;GO:0032502//developmental process gi|894216207|ref|NP_001297681.1|/0/ras-associating and dilute domain-containing protein isoform 3 [Mus musculus] 74982 838 0.52 0.536666667 0.045514659 Up 0.094268306 1700100I10Rik RIKEN cDNA 1700100I10 gene - - - - - 101544 2741 0.43 0.446666667 0.054861935 Up 0.094268306 Zfp575 zinc finger protein 575 K09228|1|1e-29|134|myb:102256930|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|85701718|ref|NP_001028377.1|/9.46436e-122/zinc finger protein 575 [Mus musculus] 100042165 5181 0.693333333 0.716666667 0.047753131 Up 0.094268306 BC005561 cDNA sequence BC005561 K12879|1|0.0|2694|cge:100755241|THO complex subunit 2 - - - gi|262205179|ref|NP_001160053.1|/0/cDNA sequence BC005561 [Mus musculus] 59033 11811 0.66 0.636666667 -0.051927792 Down 0.094268306 Slc4a8 "solute carrier family 4 (anion exchanger), member 8" "K13859|1|0.0|2114|mmu:59033|solute carrier family 4 (sodium bicarbonate cotransporter), member 8" GO:0031224//intrinsic component of membrane GO:0015301//anion:anion antiporter activity GO:0030001//metal ion transport gi|50510613|dbj|BAD32292.1|/0/mKIAA0739 protein [Mus musculus] 245865 1502 0.463333333 0.48 0.050983929 Up 0.094268306 Spag4 sperm associated antigen 4 K19347|1|4e-40|168|pss:102452375|SUN domain-containing protein 1/2 GO:0015630//microtubule cytoskeleton;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding - gi|151301071|ref|NP_631890.3|/0/sperm-associated antigen 4 protein [Mus musculus] 217194 2436 0.463333333 0.446666667 -0.052851882 Down 0.094268306 Klhl11 kelch-like 11 K10449|1|0.0|1417|mmu:217194|kelch-like protein 11 - - - gi|27369800|ref|NP_766153.1|/0/kelch-like protein 11 precursor [Mus musculus] 59083 1600 0.616666667 0.64 0.05358104 Up 0.094268306 Fetub fetuin beta K03898|1|4e-14|82.0|mgp:104912678|kininogen GO:0044421;GO:0044421;GO:0044421 GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity - "gi|148665226|gb|EDK97642.1|/0/fetuin beta, isoform CRA_a, partial [Mus musculus]" 70799 8125 0.536666667 0.52 -0.045514659 Down 0.094268306 Cep192 centrosomal protein 192 K16725|1|0.0|4827|mmu:70799|centrosomal protein CEP192 - - - gi|255003835|ref|NP_081832.1|/0/centrosomal protein of 192 kDa [Mus musculus] 72137 2081.48 7.516666667 7.446666667 -0.013498248 Down 0.093976833 Wdsub1 "WD repeat, SAM and U-box domain containing 1" K12602|1|1e-25|120|dsi:Dsimw501_GD18659|WD repeat-containing protein 61 - GO:0019787//ubiquitin-like protein transferase activity;GO:0019787//ubiquitin-like protein transferase activity GO:0032446//protein modification by small protein conjugation;GO:0032446//protein modification by small protein conjugation "gi|30048137|gb|AAH50792.1|/0/Wdsub1 protein, partial [Mus musculus]" 193116 3696.75 10.71666667 10.78666667 0.00939287 Up 0.093976833 Slu7 SLU7 splicing factor homolog (S. cerevisiae) K12819|1|0.0|1021|mmu:193116|pre-mRNA-processing factor SLU7 - - - - 18201 3518 17.77 17.69666667 -0.005966041 Down 0.093976833 Nsmaf neutral sphingomyelinase (N-SMase) activation associated factor K18953|1|0.0|1862|mmu:18201|factor associated with neutral sphingomyelinase activation GO:0044424 GO:0005488//binding;GO:0004871//signal transducer activity;GO:0016004//phospholipase activator activity GO:0006665//sphingolipid metabolic process;GO:0012502//induction of programmed cell death;GO:0044093;GO:0007154//cell communication gi|171906555|ref|NP_035075.2|/0/protein FAN [Mus musculus] 74781 3913 14.07333333 14.00333333 -0.007193793 Down 0.093976833 Wipi2 "WD repeat domain, phosphoinositide interacting 2" K17908|1|0.0|890|mmu:74781|autophagy-related protein 18 - - - gi|30409972|ref|NP_848485.1|/0/WD repeat domain phosphoinositide-interacting protein 2 [Mus musculus] 108067 1579.07 9.633333333 9.706666667 0.010940863 Up 0.093976833 Eif2b3 "eukaryotic translation initiation factor 2B, subunit 3" K03241|1|0.0|722|mmu:108067|translation initiation factor eIF-2B subunit gamma GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0030695//GTPase regulator activity;GO:0008135//translation factor activity, RNA binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0030695//GTPase regulator activity;GO:0008135//translation factor activity, RNA binding" GO:0009725//response to hormone;GO:0009746;GO:0032055//negative regulation of translation in response to stress;GO:0021782//glial cell development;GO:0009725//response to hormone;GO:0009746;GO:0032055//negative regulation of translation in response to stress;GO:0021782//glial cell development gi|110626005|ref|NP_780344.2|/0/translation initiation factor eIF-2B subunit gamma isoform 2 [Mus musculus] 74105 4891 11.83333333 11.9 0.00810505 Up 0.093976833 Gga2 "golgi associated, gamma adaptin ear containing, ARF binding protein 2" K12404|1|0.0|1041|mmu:74105|ADP-ribosylation factor-binding protein GGA GO:0030135//coated vesicle;GO:0005794//Golgi apparatus;GO:0031090//organelle membrane;GO:0030119//AP-type membrane coat adaptor complex GO:0031267//small GTPase binding GO:0015031//protein transport gi|37360224|dbj|BAC98090.1|/0/mKIAA1080 protein [Mus musculus] 108097 4278 7.13 7.203333333 0.01476259 Up 0.093976833 Prkab2 "protein kinase, AMP-activated, beta 2 non-catalytic subunit" "K07199|1|8e-139|498|mmu:108097|5'-AMP-activated protein kinase, regulatory beta subunit" GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0044459;GO:0044444//cytoplasmic part GO:0004674//protein serine/threonine kinase activity;GO:0019900//kinase binding GO:0015980//energy derivation by oxidation of organic compounds;GO:0006796//phosphate-containing compound metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0003333//amino acid transmembrane transport;GO:0022402//cell cycle process;GO:0006464//cellular protein modification process;GO:0019217//regulation of fatty acid metabolic process gi|72384347|ref|NP_892042.2|/7.00429e-138/5'-AMP-activated protein kinase subunit beta-2 [Mus musculus] 215201 3214.22 18.75333333 18.82333333 0.005375079 Up 0.093976833 Trmt2b TRM2 tRNA methyltransferase 2B K15331|1|0.0|1015|mmu:215201|tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35] - GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0008168//methyltransferase activity GO:0006399//tRNA metabolic process;GO:0006399//tRNA metabolic process;GO:0008152//metabolic process gi|269784758|ref|NP_001161467.1|/2.08681e-70/tRNA (uracil(54)-C(5))-methyltransferase homolog isoform b [Mus musculus] 14231 898 17.30333333 17.23666667 -0.005569183 Down 0.093976833 Fkbp7 FK506 binding protein 7 K09573|1|4e-126|452|mmu:14231|FK506-binding protein 7 [EC:5.2.1.8] GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0003824//catalytic activity GO:0044267//cellular protein metabolic process gi|6806909|ref|NP_034352.1|/3.33709e-125/peptidyl-prolyl cis-trans isomerase FKBP7 precursor [Mus musculus] 71949 2050 13.18666667 13.11333333 -0.008045468 Down 0.093976833 Cers5 ceramide synthase 5 K04710|1|0.0|742|mmu:71949|ceramide synthetase [EC:2.3.1.24] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0016410//N-acyltransferase activity "GO:0006672//ceramide metabolic process;GO:0006351//transcription, DNA-templated" gi|21312638|ref|NP_082291.1|/0/ceramide synthase 5 [Mus musculus] 66921 3003 8.206666667 8.273333333 0.011672354 Up 0.093976833 Prpf38b PRP38 pre-mRNA processing factor 38 (yeast) domain containing B K12850|1|6e-95|351|fca:101096333|pre-mRNA-splicing factor 38B - - - gi|73959951|ref|XP_854693.1|/5.45426e-94/PREDICTED: pre-mRNA-splicing factor 38B [Canis lupus familiaris] 13405 5576.35 9.113333333 9.043333333 -0.011124195 Down 0.093976833 Dmd "dystrophin, muscular dystrophy" K10366|1|0.0|6828|mmu:13405|dystrophin - - - - 232816 3544 7.806666667 7.736666667 -0.012994553 Down 0.093976833 Zfp628 zinc finger protein 628 K09228|1|3e-136|489|ccw:104685348|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated" gi|148276994|ref|NP_739565.2|/0/zinc finger protein 628 [Mus musculus] 270086 5317.35 7.68 7.613333333 -0.012578066 Down 0.093976833 Ogfod1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 "K05291|1|1e-36|159|aga:AgaP_AGAP002933|phosphatidylinositol glycan, class S" GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0019842//vitamin binding;GO:0043169//cation binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0019842//vitamin binding;GO:0043169//cation binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0044710;GO:0044710 gi|147901538|ref|NP_808435.3|/0/prolyl 3-hydroxylase OGFOD1 isoform 1 [Mus musculus] 69048 3193 7.376666667 7.31 -0.013097639 Down 0.093976833 Slc30a5 "solute carrier family 30 (zinc transporter), member 5" "K14692|1|0.0|1298|mmu:69048|solute carrier family 30 (zinc transporter), member 5/7" GO:0030141//secretory granule;GO:0016021//integral component of membrane;GO:0031981//nuclear lumen;GO:0044459;GO:0012505//endomembrane system GO:0046914//transition metal ion binding;GO:0046915//transition metal ion transmembrane transporter activity GO:0010038//response to metal ion;GO:0006829//zinc II ion transport;GO:0072503;GO:0015992//proton transport gi|67763826|ref|NP_075023.2|/0/zinc transporter 5 [Mus musculus] 77040 3195.11 13.18333333 13.25333333 0.007640062 Up 0.093976833 Atg16l1 autophagy related 16-like 1 (S. cerevisiae) "K17890|1|0.0|1069|mmu:77040|autophagy-related protein 16, animal type" GO:0005774//vacuolar membrane;GO:0005774//vacuolar membrane;GO:0005774//vacuolar membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0045184//establishment of protein localization;GO:0044248;GO:0045184//establishment of protein localization;GO:0044248;GO:0045184//establishment of protein localization;GO:0044248 gi|27777650|ref|NP_084122.2|/0/autophagy-related protein 16-1 isoform 2 [Mus musculus] 328801 1162.48 11.23 11.29666667 0.008539208 Up 0.093976833 Zfp414 zinc finger protein 414 K19994|1|3e-81|252|ssc:100514337|PML-RARA-regulated adapter molecule 1;K09194|3|3e-06|55.5|sko:102802378|transcription factor Sp4;K10485|4|6e-06|54.3|myd:102773583|BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1) GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|34850068|ref|NP_080988.1|/2.80653e-136/zinc finger protein 414 [Mus musculus] 72068 2775.44 11.37 11.43666667 0.008434371 Up 0.093976833 Cnot2 "CCR4-NOT transcription complex, subunit 2" K12605|1|0.0|870|pale:102887297|CCR4-NOT transcription complex subunit 2 - - - gi|752413362|ref|XP_011226967.1|/0/PREDICTED: CCR4-NOT transcription complex subunit 2 isoform X1 [Ailuropoda melanoleuca] 67998 3112.02 16.47666667 16.55 0.006406811 Up 0.093976833 Fam134c "family with sequence similarity 134, member C" K14816|1|1e-44|184|tgu:100229493|pre-60S factor REI1 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148671940|gb|EDL03887.1|/0/RIKEN cDNA 1300010M03, isoform CRA_c, partial [Mus musculus]" 19055 4858.36 8.033333333 8.1 0.011923167 Up 0.093976833 Ppp3ca "protein phosphatase 3, catalytic subunit, alpha isoform" K04348|1|0.0|1018|chx:102176770|serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16] GO:0031981//nuclear lumen;GO:0008287//protein serine/threonine phosphatase complex;GO:0031674//I band;GO:0031981//nuclear lumen;GO:0008287//protein serine/threonine phosphatase complex;GO:0031674//I band GO:0046872//metal ion binding;GO:0004723//calcium-dependent protein serine/threonine phosphatase activity;GO:0046983//protein dimerization activity;GO:0046872//metal ion binding;GO:0004723//calcium-dependent protein serine/threonine phosphatase activity;GO:0046983//protein dimerization activity GO:0014075//response to amine;GO:0007268//chemical synaptic transmission;GO:0051899//membrane depolarization;GO:0070838//divalent metal ion transport;GO:0006796//phosphate-containing compound metabolic process;GO:0001678//cellular glucose homeostasis;GO:0014733//regulation of skeletal muscle adaptation;GO:0044772//mitotic cell cycle phase transition;GO:0017156//calcium ion regulated exocytosis;GO:0006886//intracellular protein transport;GO:0010038//response to metal ion;GO:0006366//transcription from RNA polymerase II promoter;GO:0006464//cellular protein modification process;GO:0019722//calcium-mediated signaling;GO:0046649//lymphocyte activation;GO:0050796//regulation of insulin secretion;GO:0042493//response to drug;GO:0007519//skeletal muscle tissue development;GO:0014075//response to amine;GO:0007268//chemical synaptic transmission;GO:0051899//membrane depolarization;GO:0070838//divalent metal ion transport;GO:0006796//phosphate-containing compound metabolic process;GO:0001678//cellular glucose homeostasis;GO:0014733//regulation of skeletal muscle adaptation;GO:0044772//mitotic cell cycle phase transition;GO:0017156//calcium ion regulated exocytosis;GO:0006886//intracellular protein transport;GO:0010038//response to metal ion;GO:0006366//transcription from RNA polymerase II promoter;GO:0006464//cellular protein modification process;GO:0019722//calcium-mediated signaling;GO:0046649//lymphocyte activation;GO:0050796//regulation of insulin secretion;GO:0042493//response to drug;GO:0007519//skeletal muscle tissue development gi|926693529|ref|XP_013819948.1|/0/PREDICTED: serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform [Capra hircus] 101489 2967 8.33 8.4 0.012072832 Up 0.093976833 Ric8a RIC8 guanine nucleotide exchange factor A - GO:0016020//membrane;GO:0044444//cytoplasmic part GO:0030695//GTPase regulator activity;GO:0005515//protein binding;GO:0008047//enzyme activator activity GO:0048731//system development;GO:0043087//regulation of GTPase activity;GO:0007369//gastrulation;GO:0030198//extracellular matrix organization;GO:0001667//ameboidal-type cell migration;GO:0007632//visual behavior;GO:0043009//chordate embryonic development;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway gi|16716495|ref|NP_444424.1|/0/synembryn-A [Mus musculus] 229603 8043 7.92 7.85 -0.012807776 Down 0.093976833 Otud7b OTU domain containing 7B K11860|1|0.0|1453|mmu:229603|OTU domain-containing protein 7 [EC:3.4.19.12] GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding;GO:0016790//thiolester hydrolase activity;GO:0046914//transition metal ion binding GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0016579//protein deubiquitination;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0016579//protein deubiquitination gi|625189275|ref|XP_007629105.1|/0/PREDICTED: OTU domain-containing protein 7B isoform X1 [Cricetulus griseus] 18972 1634 17.02333333 17.09 0.005638839 Up 0.093976833 Pold2 "polymerase (DNA directed), delta 2, regulatory subunit" K02328|1|0.0|869|cge:100762815|DNA polymerase delta subunit 2 GO:0043231//intracellular membrane-bounded organelle GO:0034061//DNA polymerase activity GO:0006260//DNA replication gi|589919945|ref|XP_006973050.1|/0/PREDICTED: DNA polymerase delta subunit 2 [Peromyscus maniculatus bairdii] 217480 5544 0.08 0.09 0.169925001 Up 0.093685359 Dgkb "diacylglycerol kinase, beta" K00901|1|0.0|1659|mmu:217480|diacylglycerol kinase (ATP) [EC:2.7.1.107] GO:0016020//membrane;GO:0044424 GO:0046872//metal ion binding;GO:0016301//kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0007186//G-protein coupled receptor signaling pathway gi|83816899|ref|NP_848796.2|/0/diacylglycerol kinase beta [Mus musculus] 238021 1718 0.09 0.08 -0.169925001 Down 0.093685359 Fscn2 fascin actin-bundling protein 2 K17455|1|0.0|1011|mmu:238021|fascin 1/2 - - - - 320095 1882 0.073333333 0.083333333 0.184424571 Up 0.093685359 6430550D23Rik RIKEN cDNA 6430550D23 gene - - - - "gi|148674211|gb|EDL06158.1|/5.76726e-67/mCG58586, isoform CRA_a, partial [Mus musculus]" 93886 2795 0.06 0.053333333 -0.169925001 Down 0.093685359 Pcdhb15 protocadherin beta 15 K16494|1|0.0|1497|mmu:93886|protocadherin beta GO:0031224//intrinsic component of membrane - GO:0022610 gi|18087793|ref|NP_444370.1|/0/protocadherin beta-7 [Mus musculus] 26464 1811 0.06 0.053333333 -0.169925001 Down 0.093685359 Vnn3 vanin 3 K08069|1|0.0|998|mmu:26464|pantetheine hydrolase [EC:3.5.1.92] - - - "gi|148672823|gb|EDL04770.1|/0/vanin 3, partial [Mus musculus]" 14853 2508 0.1 0.113333333 0.180572246 Up 0.093685359 Gspt2 G1 to S phase transition 2 K03267|1|0.0|1165|mmu:14853|peptide chain release factor subunit 3 - - - - 432582 4002 0.073333333 0.083333333 0.184424571 Up 0.093685359 Ccdc92b coiled-coil domain containing 92B K16452|1|2e-95|353|mmu:432582|coiled-coil domain-containing protein 92 - - - - 232370 4007 0.053333333 0.06 0.169925001 Up 0.093685359 Clstn3 calsyntenin 3 K16494|1|7e-10|69.7|mgp:100538867|protocadherin beta;K16507|3|1e-09|68.9|api:100167672|protocadherin-16/23;K04600|4|1e-09|68.9|soc:105193015|cadherin EGF LAG seven-pass G-type receptor 1 - - - - 319634 4654 0.06 0.053333333 -0.169925001 Down 0.093685359 Efcab5 EF-hand calcium binding domain 5 K17498|1|2e-18|98.2|phu:Phum_PHUM465390|transcription factor SPN1;K19538|5|2e-14|85.1|ssc:100153380|retinitis pigmentosa 1 - - - gi|568974380|ref|XP_006533586.1|/0/PREDICTED: EF-hand calcium-binding domain-containing protein 5 isoform X2 [Mus musculus] 329078 5023 0.05 0.056666667 0.180572246 Up 0.093685359 Emx2os Emx2 opposite strand/antisense transcript (non-protein coding) K10591|1|1e-05|56.2|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] - - - - 77771 10266 0.05 0.056666667 0.180572246 Up 0.093685359 Csrnp3 cysteine-serine-rich nuclear protein 3 K17494|1|0.0|980|mmu:77771|cysteine/serine-rich nuclear protein - - - - 71724 4360 0.05 0.056666667 0.180572246 Up 0.093685359 Aox3 aldehyde oxidase 3 K00157|1|0.0|2586|mmu:71724|aldehyde oxidase [EC:1.2.3.1] - GO:0051536//iron-sulfur cluster binding;GO:0046914//transition metal ion binding GO:0044710 gi|114205420|ref|NP_076106.2|/0/aldehyde oxidase 3 [Mus musculus] 213956 3010 0.053333333 0.06 0.169925001 Up 0.093685359 Fam83f "family with sequence similarity 83, member F" K16805|1|6e-50|202|xtr:100496367|protein FAM83D - - - gi|156564376|ref|NP_666098.2|/0/protein FAM83F [Mus musculus] 664702 1795 0.06 0.053333333 -0.169925001 Down 0.093685359 A530088E08Rik RIKEN cDNA A530088E08 gene K17634|1|6e-61|238|mmu:320484|RAS protein activator-like 3 GO:0044464 GO:0008289//lipid binding GO:0007264//small GTPase mediated signal transduction "gi|148708368|gb|EDL40315.1|/1.45566e-85/mCG125477, isoform CRA_c, partial [Mus musculus]" 75863 1239 0.123333333 0.11 -0.165059246 Down 0.093685359 Clec4g "C-type lectin domain family 4, member g" K10061|1|3e-153|543|mmu:75863|C-type lectin superfamily 4 member G - - - - 71301 938 0.06 0.053333333 -0.169925001 Down 0.093685359 4930593A02Rik RIKEN cDNA 4930593A02 gene - - - - - 66627 1548 9.68 9.74 0.008914725 Up 0.093187032 Ogfod2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 "K13645|1|8e-08|61.2|pbi:103054432|procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 [EC:1.14.11.4]" - "GO:0046914//transition metal ion binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0019842//vitamin binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen" GO:0044710 gi|21313390|ref|NP_079947.1|/3.75328e-172/2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 [Mus musculus] 18799 2674.59 10.77666667 10.84 0.00845375 Up 0.093187032 Plcd1 "phospholipase C, delta 1" "K05857|1|0.0|899|mmu:18799|phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]" GO:0044425;GO:0005740//mitochondrial envelope;GO:0044425;GO:0005740//mitochondrial envelope;GO:0044425;GO:0005740//mitochondrial envelope GO:0004629//phospholipase C activity;GO:0005515//protein binding;GO:0060089;GO:0046872//metal ion binding;GO:0043168//anion binding;GO:0008289//lipid binding;GO:0004629//phospholipase C activity;GO:0005515//protein binding;GO:0060089;GO:0046872//metal ion binding;GO:0043168//anion binding;GO:0008289//lipid binding;GO:0004629//phospholipase C activity;GO:0005515//protein binding;GO:0060089;GO:0046872//metal ion binding;GO:0043168//anion binding;GO:0008289//lipid binding GO:0032959//inositol trisphosphate biosynthetic process;GO:0048568//embryonic organ development;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0006629//lipid metabolic process;GO:0010038//response to metal ion;GO:0006950//response to stress;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0034694//response to prostaglandin;GO:0014061//regulation of norepinephrine secretion;GO:0032959//inositol trisphosphate biosynthetic process;GO:0048568//embryonic organ development;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0006629//lipid metabolic process;GO:0010038//response to metal ion;GO:0006950//response to stress;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0034694//response to prostaglandin;GO:0014061//regulation of norepinephrine secretion;GO:0032959//inositol trisphosphate biosynthetic process;GO:0048568//embryonic organ development;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0006629//lipid metabolic process;GO:0010038//response to metal ion;GO:0006950//response to stress;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0034694//response to prostaglandin;GO:0014061//regulation of norepinephrine secretion "gi|9790167|ref|NP_062650.1|/0/1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 2 [Mus musculus]" 94185 3626 5.78 5.723333333 -0.014213859 Down 0.093187032 Tnfrsf21 "tumor necrosis factor receptor superfamily, member 21" K05157|1|0.0|1243|mmu:94185|tumor necrosis factor receptor superfamily member 21 GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane - GO:0070997//neuron death;GO:0007154//cell communication "gi|16741137|gb|AAH16420.1|/0/Tumor necrosis factor receptor superfamily, member 21 [Mus musculus]" 12412 1274 11.24666667 11.31 0.008101456 Up 0.093187032 Cbx1 chromobox 1 K11585|1|2e-89|331|cjc:100405723|chromobox protein 1 "GO:0015630//microtubule cytoskeleton;GO:0000790//nuclear chromatin;GO:0045120//pronucleus;GO:0000775//chromosome, centromeric region" GO:0005515//protein binding "GO:0006351//transcription, DNA-templated" gi|675660465|ref|XP_002748531.2|/1.95877e-88/PREDICTED: chromobox protein homolog 1 [Callithrix jacchus] 110012 1101 11.93333333 11.99666667 0.007636515 Up 0.093187032 Tpgs1 tubulin polyglutamylase complex subunit 1 K16581|1|3e-151|536|mmu:110012|tubulin polyglutamylase complex subunit 1 GO:0005815//microtubule organizing center;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0070739//protein-glutamic acid ligase activity;GO:0015631//tubulin binding;GO:0019887//protein kinase regulator activity GO:0048869//cellular developmental process;GO:0051640//organelle localization;GO:0007267//cell-cell signaling;GO:0048232//male gamete generation;GO:0018200//peptidyl-glutamic acid modification;GO:0003006//developmental process involved in reproduction;GO:0044707 gi|22507341|ref|NP_683736.1|/2.47791e-150/tubulin polyglutamylase complex subunit 1 [Mus musculus] 50850 4694.78 6.526666667 6.586666667 0.013202182 Up 0.093187032 Spast spastin K13254|1|0.0|987|mmu:50850|spastin [EC:3.6.4.3] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0031982//vesicle;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0031982//vesicle "GO:0032550;GO:0042623//ATPase activity, coupled;GO:0015631//tubulin binding;GO:0032550;GO:0042623//ATPase activity, coupled;GO:0015631//tubulin binding" GO:0048869//cellular developmental process;GO:0048731//system development;GO:0051259//protein oligomerization;GO:0000920//cell separation after cytokinesis;GO:0000226//microtubule cytoskeleton organization;GO:0016482//cytosolic transport;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0051259//protein oligomerization;GO:0000920//cell separation after cytokinesis;GO:0000226//microtubule cytoskeleton organization;GO:0016482//cytosolic transport gi|28279482|gb|AAH46286.1|/0/Spastin [Mus musculus] 269338 4362 11.38333333 11.32333333 -0.00762436 Down 0.093187032 Vps39 VPS39 HOPS complex subunit K20183|1|0.0|1643|mmu:269338|Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39 GO:0005770//late endosome;GO:0005764//lysosome;GO:0005774//vacuolar membrane;GO:0000323//lytic vacuole;GO:0005774//vacuolar membrane;GO:0000323//lytic vacuole;GO:0005774//vacuolar membrane GO:0005488//binding;GO:0030695//GTPase regulator activity;GO:0005488//binding;GO:0005488//binding GO:0015031//protein transport;GO:0015031//protein transport;GO:0015031//protein transport gi|568917195|ref|XP_006499661.1|/0/PREDICTED: vam6/Vps39-like protein isoform X1 [Mus musculus] 66690 2878 9.946666667 10.01 0.009156939 Up 0.093187032 Tmem186 transmembrane protein 186 - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|27228988|ref|NP_079984.2|/1.00364e-121/transmembrane protein 186 [Mus musculus] 329908 10601 7.103333333 7.163333333 0.01213489 Up 0.093187032 Usp24 ubiquitin specific peptidase 24 K11840|1|0.0|4787|mmu:329908|ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12] - "GO:0016790//thiolester hydrolase activity;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019941//modification-dependent protein catabolic process gi|260064007|ref|NP_899048.2|/0/ubiquitin carboxyl-terminal hydrolase 24 [Mus musculus] 12874 9152 6.916666667 6.98 0.013150106 Up 0.093187032 Cpd carboxypeptidase D K07752|1|0.0|2550|mmu:12874|carboxypeptidase D [EC:3.4.17.22] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding;GO:0004180//carboxypeptidase activity GO:0070669//response to interleukin-2;GO:0019538//protein metabolic process gi|150378501|ref|NP_031780.2|/0/carboxypeptidase D precursor [Mus musculus] 26420 4677 10.97333333 10.91333333 -0.007910014 Down 0.093187032 Mapk9 mitogen-activated protein kinase 9 K04440|1|0.0|769|ngi:103749366|c-Jun N-terminal kinase [EC:2.7.11.24] GO:0031981//nuclear lumen;GO:0005829//cytosol;GO:0031981//nuclear lumen;GO:0005829//cytosol;GO:0031981//nuclear lumen;GO:0005829//cytosol;GO:0031981//nuclear lumen;GO:0005829//cytosol GO:0016505//peptidase activator activity involved in apoptotic process;GO:0032550;GO:0019901//protein kinase binding;GO:0016909//SAP kinase activity;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0032550;GO:0019901//protein kinase binding;GO:0016909//SAP kinase activity;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0032550;GO:0019901//protein kinase binding;GO:0016909//SAP kinase activity;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0032550;GO:0019901//protein kinase binding;GO:0016909//SAP kinase activity "GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0070555//response to interleukin-1;GO:0001932//regulation of protein phosphorylation;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006809//nitric oxide biosynthetic process;GO:0010243//response to organonitrogen compound;GO:0016567//protein ubiquitination;GO:0009967//positive regulation of signal transduction;GO:0010742//macrophage derived foam cell differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0009411//response to UV;GO:0032305//positive regulation of icosanoid secretion;GO:0007254//JNK cascade;GO:0009605//response to external stimulus;GO:0001516//prostaglandin biosynthetic process;GO:0001819//positive regulation of cytokine production;GO:0007399//nervous system development;GO:0006605//protein targeting;GO:0070848//response to growth factor;GO:0007166//cell surface receptor signaling pathway;GO:0010038//response to metal ion;GO:0008637//apoptotic mitochondrial changes;GO:0030030//cell projection organization;GO:0034612//response to tumor necrosis factor;GO:0032496//response to lipopolysaccharide;GO:0006355//regulation of transcription, DNA-templated;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0070555//response to interleukin-1;GO:0001932//regulation of protein phosphorylation;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006809//nitric oxide biosynthetic process;GO:0010243//response to organonitrogen compound;GO:0016567//protein ubiquitination;GO:0009967//positive regulation of signal transduction;GO:0010742//macrophage derived foam cell differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0009411//response to UV;GO:0032305//positive regulation of icosanoid secretion;GO:0007254//JNK cascade;GO:0009605//response to external stimulus;GO:0001516//prostaglandin biosynthetic process;GO:0001819//positive regulation of cytokine production;GO:0007399//nervous system development;GO:0006605//protein targeting;GO:0070848//response to growth factor;GO:0007166//cell surface receptor signaling pathway;GO:0010038//response to metal ion;GO:0008637//apoptotic mitochondrial changes;GO:0030030//cell projection organization;GO:0034612//response to tumor necrosis factor;GO:0032496//response to lipopolysaccharide;GO:0006355//regulation of transcription, DNA-templated;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0070555//response to interleukin-1;GO:0001932//regulation of protein phosphorylation;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006809//nitric oxide biosynthetic process;GO:0010243//response to organonitrogen compound;GO:0016567//protein ubiquitination;GO:0009967//positive regulation of signal transduction;GO:0010742//macrophage derived foam cell differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0009411//response to UV;GO:0032305//positive regulation of icosanoid secretion;GO:0007254//JNK cascade;GO:0009605//response to external stimulus;GO:0001516//prostaglandin biosynthetic process;GO:0001819//positive regulation of cytokine production;GO:0007399//nervous system development;GO:0006605//protein targeting;GO:0070848//response to growth factor;GO:0007166//cell surface receptor signaling pathway;GO:0010038//response to metal ion;GO:0008637//apoptotic mitochondrial changes;GO:0030030//cell projection organization;GO:0034612//response to tumor necrosis factor;GO:0032496//response to lipopolysaccharide;GO:0006355//regulation of transcription, DNA-templated;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0070555//response to interleukin-1;GO:0001932//regulation of protein phosphorylation;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006809//nitric oxide biosynthetic process;GO:0010243//response to organonitrogen compound;GO:0016567//protein ubiquitination;GO:0009967//positive regulation of signal transduction;GO:0010742//macrophage derived foam cell differentiation;GO:0000904//cell morphogenesis involved in differentiation;GO:0009411//response to UV;GO:0032305//positive regulation of icosanoid secretion;GO:0007254//JNK cascade;GO:0009605//response to external stimulus;GO:0001516//prostaglandin biosynthetic process;GO:0001819//positive regulation of cytokine production;GO:0007399//nervous system development;GO:0006605//protein targeting;GO:0070848//response to growth factor;GO:0007166//cell surface receptor signaling pathway;GO:0010038//response to metal ion;GO:0008637//apoptotic mitochondrial changes;GO:0030030//cell projection organization;GO:0034612//response to tumor necrosis factor;GO:0032496//response to lipopolysaccharide;GO:0006355//regulation of transcription, DNA-templated" gi|254750733|ref|NP_001157143.1|/0/mitogen-activated protein kinase 9 isoform beta2 [Mus musculus] 20352 3946 7.153333333 7.09 -0.012830043 Down 0.093187032 Sema4b "sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B" K06521|1|0.0|1555|mmu:20352|semaphorin 4 GO:0031224//intrinsic component of membrane - GO:0048731//system development;GO:0048869//cellular developmental process gi|50511083|dbj|BAD32527.1|/0/mKIAA1745 protein [Mus musculus] 263406 4955 6.67 6.613333333 -0.012309142 Down 0.093187032 Plekhg3 "pleckstrin homology domain containing, family G (with RhoGef domain) member 3" K05769|1|5e-32|143|nve:NEMVE_v1g92887|Rho guanine nucleotide exchange factor 4 - - - gi|568979672|ref|XP_006515943.1|/0/PREDICTED: pleckstrin homology domain-containing family G member 3 isoform X10 [Mus musculus] 67075 4216.54 6.62 6.56 -0.013135402 Down 0.093187032 Magt1 magnesium transporter 1 K19478|1|0.0|663|mmu:67075|magnesium transporter 1 GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031224//intrinsic component of membrane GO:0046873//metal ion transmembrane transporter activity;GO:0046873//metal ion transmembrane transporter activity GO:0050877//neurological system process;GO:0070838//divalent metal ion transport;GO:0019725//cellular homeostasis;GO:0050877//neurological system process;GO:0070838//divalent metal ion transport;GO:0019725//cellular homeostasis gi|298676496|ref|NP_080228.4|/0/magnesium transporter protein 1 [Mus musculus] 56637 8298 6.876666667 6.82 -0.011937676 Down 0.093187032 Gsk3b glycogen synthase kinase 3 beta K03083|1|0.0|775|tup:102476038|glycogen synthase kinase 3 beta [EC:2.7.11.26] GO:0031981//nuclear lumen;GO:0044425;GO:0043234//protein complex;GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0030425//dendrite GO:0051018//protein kinase A binding;GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0008092//cytoskeletal protein binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0004672//protein kinase activity;GO:0035254//glutamate receptor binding;GO:0032550 GO:0007017//microtubule-based process;GO:0051348//negative regulation of transferase activity;GO:0006984//ER-nucleus signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0006461//protein complex assembly;GO:0048017//inositol lipid-mediated signaling;GO:0005978//glycogen biosynthetic process;GO:0009612//response to mechanical stimulus;GO:0038127//ERBB signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0007163//establishment or maintenance of cell polarity;GO:0072698;GO:0009896;GO:0006935//chemotaxis;GO:0001952//regulation of cell-matrix adhesion;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0045597//positive regulation of cell differentiation;GO:0022402//cell cycle process;GO:0006611//protein export from nucleus;GO:0031345//negative regulation of cell projection organization;GO:0006996//organelle organization;GO:0010721//negative regulation of cell development;GO:0043393//regulation of protein binding;GO:0044026//DNA hypermethylation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0000768//syncytium formation by plasma membrane fusion;GO:0048511//rhythmic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0010038//response to metal ion;GO:0021987//cerebral cortex development;GO:0012502//induction of programmed cell death;GO:0048167//regulation of synaptic plasticity;GO:0043405//regulation of MAP kinase activity;GO:0035914//skeletal muscle cell differentiation;GO:0048870//cell motility gi|562876529|ref|XP_006166047.1|/0/PREDICTED: glycogen synthase kinase-3 beta isoform X2 [Tupaia chinensis] 69456 1550 6.66 6.716666667 0.012223256 Up 0.093187032 Commd10 COMM domain containing 10 - - - - gi|569004463|ref|XP_006526287.1|/8.54296e-102/PREDICTED: COMM domain-containing protein 10 isoform X1 [Mus musculus] 50793 6310.49 5.7 5.643333333 -0.014414352 Down 0.093187032 Orc3 "origin recognition complex, subunit 3" K02605|1|0.0|1359|mmu:50793|origin recognition complex subunit 3 GO:0043231//intracellular membrane-bounded organelle;GO:0000808//origin recognition complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000808//origin recognition complex GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process;GO:0006259//DNA metabolic process gi|227116263|ref|NP_001153035.1|/0/origin recognition complex subunit 3 isoform 2 [Mus musculus] 219022 1952.15 5.54 5.596666667 0.014681848 Up 0.093187032 Ttc5 tetratricopeptide repeat domain 5 - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006366//transcription from RNA polymerase II promoter;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0006366//transcription from RNA polymerase II promoter gi|124358948|ref|NP_001074418.1|/0/tetratricopeptide repeat protein 5 isoform a [Mus musculus] 73827 2366 5.496666667 5.44 -0.014950341 Down 0.093187032 Tmem198b transmembrane protein 198b "K03847|1|4e-06|56.2|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - gi|30017375|ref|NP_835167.1|/4.66651e-130/uncharacterized protein LOC73827 [Mus musculus] 234076 4533 7.093333333 7.153333333 0.012151925 Up 0.093187032 Tmco3 transmembrane and coiled-coil domains 3 K10591|1|7e-06|56.6|cge:100755507|E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0015078//hydrogen ion transmembrane transporter activity GO:0006811//ion transport;GO:0044763 gi|26986589|ref|NP_758486.1|/0/transmembrane and coiled-coil domain-containing protein 3 precursor [Mus musculus] 19272 6177 5.96 5.903333333 -0.013782524 Down 0.093187032 Ptprk "protein tyrosine phosphatase, receptor type, K" K06776|1|0.0|2856|mmu:19272|receptor-type tyrosine-protein phosphatase kappa [EC:3.1.3.48] GO:0031513//nonmotile primary cilium;GO:0043005//neuron projection;GO:0070161;GO:0044297//cell body;GO:0016021//integral component of membrane;GO:0031252//cell leading edge GO:0004725//protein tyrosine phosphatase activity;GO:0019900//kinase binding "GO:0006351//transcription, DNA-templated;GO:0034613//cellular protein localization;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0000302//response to reactive oxygen species;GO:0009411//response to UV;GO:0008285//negative regulation of cell proliferation;GO:0007044//cell-substrate junction assembly;GO:0022610;GO:0030030//cell projection organization;GO:0051726//regulation of cell cycle;GO:0006470//protein dephosphorylation;GO:0016477//cell migration" gi|6679561|ref|NP_033009.1|/0/receptor-type tyrosine-protein phosphatase kappa precursor [Mus musculus] 11800 3760.16 10.68333333 10.62 -0.00857809 Down 0.093187032 Api5 apoptosis inhibitor 5 - - - - - 100037258 5190 8.143333333 8.203333333 0.010590794 Up 0.093187032 Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 K09523|1|0.0|927|mmu:100037258|DnaJ homolog subfamily C member 3 - - - - 217116 2606 0.063333333 0.056666667 -0.160464672 Down 0.092970777 Spata20 spermatogenesis associated 20 - - - GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|46485467|ref|NP_659076.2|/0/spermatogenesis-associated protein 20 [Mus musculus] 70370 2922 0.056666667 0.063333333 0.160464672 Up 0.092970777 Fbln7 fibulin 7 K17342|1|0.0|857|mmu:70370|fibulin 7 GO:0031012//extracellular matrix GO:0005539//glycosaminoglycan binding GO:0022610 "gi|148696273|gb|EDL28220.1|/0/RIKEN cDNA 1600015H20, isoform CRA_a, partial [Mus musculus]" 105244662 2003 0.136666667 0.123333333 -0.148098639 Down 0.092970777 Cyp4x1os "cytochrome P450, family 4, subfamily x, polypeptide 1, opposite strand" "K11290|1|9e-13|60.8|rno:317165|template-activating factor I;K07428|3|2e-11|73.9|mmu:81906|cytochrome P450, family 4, subfamily X [EC:1.14.14.1]" - - - - 74054 3970 0.12 0.133333333 0.152003093 Up 0.092970777 4931406B18Rik RIKEN cDNA 4931406B18 gene K06773|1|1e-84|318|mcc:719890|opioid binding protein/cell adhesion molecule-like;K06549|4|5e-16|90.1|mdo:100028318|sialic acid binding Ig-like lectin 5/14 - - - "gi|148690716|gb|EDL22663.1|/0/RIKEN cDNA 4931406B18, partial [Mus musculus]" 545253 2187 0.093333333 0.103333333 0.146841388 Up 0.092970777 Gm5820 predicted gene 5820 - - - - gi|85702103|ref|NP_001028961.1|/2.52927e-66/uncharacterized protein LOC545253 [Mus musculus] 69591 1054 0.1 0.09 -0.152003093 Down 0.092970777 Mdrl mitochondrial dynamic related lncRNA - - - - - 233066 1105 0.093333333 0.083333333 -0.163498732 Down 0.092970777 Syne4 "spectrin repeat containing, nuclear envelope family member 4" K19346|1|4e-07|58.5|tru:101078404|nesprin-2 GO:0031301//integral component of organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031301//integral component of organelle membrane;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0005515//protein binding GO:0030859//polarized epithelial cell differentiation;GO:0030859//polarized epithelial cell differentiation gi|23956370|ref|NP_705805.1|/5.88248e-171/nesprin-4 isoform 1 [Mus musculus] 12298 7717 0.06 0.066666667 0.152003093 Up 0.092970777 Cacnb4 "calcium channel, voltage-dependent, beta 4 subunit" K04865|1|0.0|858|rno:58942|voltage-dependent calcium channel beta-4 GO:0034704//calcium channel complex;GO:0044459;GO:0044444//cytoplasmic part;GO:0034704//calcium channel complex;GO:0044459;GO:0044444//cytoplasmic part;GO:0034704//calcium channel complex;GO:0034704//calcium channel complex;GO:0034704//calcium channel complex;GO:0044459;GO:0044444//cytoplasmic part GO:0005245//voltage-gated calcium channel activity;GO:0019900//kinase binding;GO:0005245//voltage-gated calcium channel activity;GO:0019900//kinase binding;GO:0005245//voltage-gated calcium channel activity;GO:0019900//kinase binding;GO:0005245//voltage-gated calcium channel activity;GO:0019900//kinase binding;GO:0005245//voltage-gated calcium channel activity;GO:0019900//kinase binding GO:0007186//G-protein coupled receptor signaling pathway;GO:0007270//neuron-neuron synaptic transmission;GO:0048741//skeletal muscle fiber development;GO:0009150//purine ribonucleotide metabolic process;GO:0006816//calcium ion transport;GO:0050851//antigen receptor-mediated signaling pathway;GO:0048537//mucosal-associated lymphoid tissue development;GO:0007601//visual perception;GO:0006935//chemotaxis;GO:0034220//ion transmembrane transport;GO:0030098//lymphocyte differentiation;GO:0042391//regulation of membrane potential;GO:0015812//gamma-aminobutyric acid transport;GO:0006875//cellular metal ion homeostasis;GO:0008344//adult locomotory behavior;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007270//neuron-neuron synaptic transmission;GO:0048741//skeletal muscle fiber development;GO:0009150//purine ribonucleotide metabolic process;GO:0006816//calcium ion transport;GO:0050851//antigen receptor-mediated signaling pathway;GO:0048537//mucosal-associated lymphoid tissue development;GO:0007601//visual perception;GO:0006935//chemotaxis;GO:0034220//ion transmembrane transport;GO:0030098//lymphocyte differentiation;GO:0042391//regulation of membrane potential;GO:0015812//gamma-aminobutyric acid transport;GO:0006875//cellular metal ion homeostasis;GO:0008344//adult locomotory behavior;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007270//neuron-neuron synaptic transmission;GO:0048741//skeletal muscle fiber development;GO:0009150//purine ribonucleotide metabolic process;GO:0006816//calcium ion transport;GO:0050851//antigen receptor-mediated signaling pathway;GO:0048537//mucosal-associated lymphoid tissue development;GO:0007601//visual perception;GO:0034220//ion transmembrane transport;GO:0030098//lymphocyte differentiation;GO:0015812//gamma-aminobutyric acid transport;GO:0006875//cellular metal ion homeostasis;GO:0008344//adult locomotory behavior;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007270//neuron-neuron synaptic transmission;GO:0048741//skeletal muscle fiber development;GO:0009150//purine ribonucleotide metabolic process;GO:0006816//calcium ion transport;GO:0050851//antigen receptor-mediated signaling pathway;GO:0048537//mucosal-associated lymphoid tissue development;GO:0007601//visual perception;GO:0034220//ion transmembrane transport;GO:0030098//lymphocyte differentiation;GO:0015812//gamma-aminobutyric acid transport;GO:0006875//cellular metal ion homeostasis;GO:0008344//adult locomotory behavior;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007270//neuron-neuron synaptic transmission;GO:0048741//skeletal muscle fiber development;GO:0009150//purine ribonucleotide metabolic process;GO:0006816//calcium ion transport;GO:0050851//antigen receptor-mediated signaling pathway;GO:0048537//mucosal-associated lymphoid tissue development;GO:0007601//visual perception;GO:0006935//chemotaxis;GO:0034220//ion transmembrane transport;GO:0030098//lymphocyte differentiation;GO:0042391//regulation of membrane potential;GO:0015812//gamma-aminobutyric acid transport;GO:0006875//cellular metal ion homeostasis;GO:0008344//adult locomotory behavior gi|74177350|dbj|BAE34578.1|/0/unnamed protein product [Mus musculus] 100041433 2953 0.093333333 0.083333333 -0.163498732 Down 0.092970777 Gm13247 zinc finger protein 981 K09228|1|0.0|1035|mmu:102632968|KRAB domain-containing zinc finger protein - - - gi|295293068|ref|NP_001171238.1|/0/reduced expression 2 [Mus musculus] 271508 2362 0.083333333 0.093333333 0.163498732 Up 0.092970777 4933408B17Rik RIKEN cDNA 4933408B17 gene K11321|1|1e-126|456|mmu:271508|bromodomain-containing protein 8 - - - gi|283484014|ref|NP_808441.2|/1.18758e-125/uncharacterized protein LOC271508 [Mus musculus] 67666 1433 0.136666667 0.123333333 -0.148098639 Down 0.092970777 Hapln3 hyaluronan and proteoglycan link protein 3 K06852|1|0.0|727|mmu:67666|hyaluronan and proteoglycan link protein 3 GO:0031012//extracellular matrix - GO:0022610 gi|564328981|ref|XP_006229459.1|/0/PREDICTED: hyaluronan and proteoglycan link protein 3 isoform X1 [Rattus norvegicus] 54215 2458 0.086666667 0.096666667 0.157541277 Up 0.092970777 Cd160 CD160 antigen K06542|1|3e-105|385|mmu:54215|CD160 antigen GO:0031225//anchored component of membrane;GO:0031225//anchored component of membrane;GO:0031225//anchored component of membrane GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0004888//transmembrane signaling receptor activity GO:0042742//defense response to bacterium;GO:0042742//defense response to bacterium;GO:0042742//defense response to bacterium gi|254553382|ref|NP_001156969.1|/9.64263e-78/CD160 antigen isoform b precursor [Mus musculus] 71864 2395 0.083333333 0.093333333 0.163498732 Up 0.092970777 Fam217a "family with sequence similarity 217, member A" - - - - gi|568982056|ref|XP_006516846.1|/0/PREDICTED: protein FAM217A isoform X2 [Mus musculus] 19743 2316 0.09 0.1 0.152003093 Up 0.092970777 Rhag Rhesus blood group-associated A glycoprotein K06580|1|0.0|806|mmu:19743|ammonium transporter Rh GO:0031224//intrinsic component of membrane GO:0008092//cytoskeletal protein binding;GO:0008509//anion transmembrane transporter activity GO:0050801//ion homeostasis;GO:0015696//ammonium transport;GO:0015669 gi|6755322|ref|NP_035399.1|/0/ammonium transporter Rh type A precursor [Mus musculus] 670558 2817 0.103333333 0.093333333 -0.146841388 Down 0.092970777 H60c histocompatibility 60c - GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0031225//anchored component of membrane GO:0005102//receptor binding GO:0001819//positive regulation of cytokine production;GO:0030101//natural killer cell activation;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0014070//response to organic cyclic compound;GO:0002696//positive regulation of leukocyte activation;GO:0006809//nitric oxide biosynthetic process gi|568964756|ref|XP_006512548.1|/1.77323e-139/PREDICTED: histocompatibility 60c isoform X1 [Mus musculus] 17864 4804 0.063333333 0.056666667 -0.160464672 Down 0.092970777 Mybl1 myeloblastosis oncogene-like 1 K09421|1|0.0|1451|mmu:17864|myb-related protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148682340|gb|EDL14287.1|/0/myeloblastosis oncogene-like 1, isoform CRA_a, partial [Mus musculus]" 245446 3935 0.093333333 0.103333333 0.146841388 Up 0.092970777 Slitrk4 "SLIT and NTRK-like family, member 4" K06838|1|5e-29|133|xtr:100036682|slit 1;K06839|5|2e-28|131|bmor:101736444|slit 2 GO:0031224//intrinsic component of membrane - GO:0048667//cell morphogenesis involved in neuron differentiation "gi|148710252|gb|EDL42198.1|/0/SLIT and NTRK-like family, member 4, isoform CRA_b [Mus musculus]" 105892 870 0.063333333 0.056666667 -0.160464672 Down 0.092970777 9030619P08Rik lymphocyte antigen 6 complex pseudogene K06846|1|1e-24|75.1|mmu:546644|lymphocyte antigen 6 complex locus protein D/E/G6/H GO:0044425;GO:0009986//cell surface - - gi|148697528|gb|EDL29475.1|/1.3143e-47/mCG22120 [Mus musculus] 74051 10392.61 0.096666667 0.086666667 -0.157541277 Down 0.092970777 Steap2 six transmembrane epithelial antigen of prostate 2 K14738|1|0.0|935|mmu:74051|metalloreductase STEAP2 [EC:1.16.1.-] GO:0005768//endosome;GO:0031228//intrinsic component of Golgi membrane;GO:0005798//Golgi-associated vesicle;GO:0005768//endosome;GO:0031228//intrinsic component of Golgi membrane;GO:0005798//Golgi-associated vesicle;GO:0005768//endosome;GO:0031228//intrinsic component of Golgi membrane;GO:0005798//Golgi-associated vesicle;GO:0005768//endosome;GO:0031228//intrinsic component of Golgi membrane;GO:0005798//Golgi-associated vesicle;GO:0005768//endosome;GO:0031228//intrinsic component of Golgi membrane;GO:0005798//Golgi-associated vesicle;GO:0005768//endosome;GO:0031228//intrinsic component of Golgi membrane;GO:0005798//Golgi-associated vesicle GO:0043169//cation binding;GO:0036094//small molecule binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0036094//small molecule binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0036094//small molecule binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0036094//small molecule binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0036094//small molecule binding;GO:0003824//catalytic activity;GO:0043169//cation binding;GO:0003824//catalytic activity GO:0044710;GO:0006892//post-Golgi vesicle-mediated transport;GO:0009719;GO:0055080//cation homeostasis;GO:0006091//generation of precursor metabolites and energy;GO:0006887//exocytosis;GO:0044710;GO:0006892//post-Golgi vesicle-mediated transport;GO:0009719;GO:0055080//cation homeostasis;GO:0006091//generation of precursor metabolites and energy;GO:0006887//exocytosis;GO:0044710;GO:0006892//post-Golgi vesicle-mediated transport;GO:0009719;GO:0055080//cation homeostasis;GO:0006091//generation of precursor metabolites and energy;GO:0006887//exocytosis;GO:0044710;GO:0006892//post-Golgi vesicle-mediated transport;GO:0009719;GO:0055080//cation homeostasis;GO:0006091//generation of precursor metabolites and energy;GO:0006887//exocytosis;GO:0044710;GO:0006892//post-Golgi vesicle-mediated transport;GO:0009719;GO:0055080//cation homeostasis;GO:0006091//generation of precursor metabolites and energy;GO:0006887//exocytosis;GO:0044710;GO:0006892//post-Golgi vesicle-mediated transport;GO:0009719;GO:0055080//cation homeostasis;GO:0006091//generation of precursor metabolites and energy;GO:0006887//exocytosis gi|550822105|ref|NP_001272400.1|/0/metalloreductase STEAP2 isoform 2 [Mus musculus] 16559 3098 0.066666667 0.06 -0.152003093 Down 0.092970777 Kif17 kinesin family member 17 K20198|1|0.0|996|cmy:102933995|kinesin family member 17 GO:0005875//microtubule associated complex GO:0003774//motor activity;GO:0032550 GO:0006928//movement of cell or subcellular component;GO:0045184//establishment of protein localization;GO:0006810//transport gi|13487898|ref|NP_034753.1|/0/kinesin-like protein KIF17 isoform 1 [Mus musculus] 259051 2912 0.09 0.1 0.152003093 Up 0.092970777 Olfr658 olfactory receptor 658 K04257|1|9e-174|613|mmu:259051|olfactory receptor GO:0016020//membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|22128853|ref|NP_667260.1|/7.42313e-173/olfactory receptor 658 [Mus musculus] 381404 2580 0.1 0.09 -0.152003093 Down 0.092970777 Pabpc1l "poly(A) binding protein, cytoplasmic 1-like" K13126|1|0.0|1174|mmu:381404|polyadenylate-binding protein - - - - 235582 4090 0.666666667 0.646666667 -0.043943348 Down 0.092923765 Glyctk glycerate kinase K15788|1|0.0|917|mmu:235582|glycerate kinase [EC:2.7.1.31] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0016301//kinase activity;GO:0032550;GO:0016301//kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|88759352|ref|NP_001034675.1|/0/glycerate kinase [Mus musculus] 266815 2489 0.773333333 0.753333333 -0.037802033 Down 0.092923765 Mill1 MHC I like leukocyte 1 "K06751|1|8e-40|168|ssc:100626428|major histocompatibility complex, class I" - - - - 319545 2892 0.54 0.556666667 0.04385429 Up 0.092923765 D430020J02Rik RIKEN cDNA D430020J02 gene "K10279|1|2e-26|124|fpg:101911127|F-box and leucine-rich repeat protein 13;K14684|3|7e-22|108|ngi:103726559|solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41;K14702|4|2e-14|84.0|cmy:102932003|solute carrier family 26 (sodium-independent chloride/iodide transporter), member 4;K04257|5|6e-12|75.9|tup:102483054|olfactory receptor" - - - gi|672059154|ref|XP_008763709.1|/0/PREDICTED: MLV-related proviral Env polyprotein-like [Rattus norvegicus] 72180 2770 0.836666667 0.86 0.039683701 Up 0.092923765 Zfp661 zinc finger protein 661 K09228|1|0.0|902|mmu:72180|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148696250|gb|EDL28197.1|/0/zinc finger protein 661, isoform CRA_a, partial [Mus musculus]" 622665 2003 0.813333333 0.793333333 -0.035919574 Down 0.092923765 Ccdc17 coiled-coil domain containing 17 K16806|1|6e-06|55.5|bfo:BRAFLDRAFT_125888|MAP7 domain-containing protein 1 - - - gi|85702302|ref|NP_001033005.1|/0/coiled-coil domain-containing protein 17 [Mus musculus] 269642 6529 0.6 0.583333333 -0.040641984 Down 0.092923765 Nat8l N-acetyltransferase 8-like K18309|1|2e-124|450|mmu:269642|aspartate N-acetyltransferase [EC:2.3.1.17] GO:0005740//mitochondrial envelope;GO:0005789//endoplasmic reticulum membrane GO:0008080//N-acetyltransferase activity GO:0043270//positive regulation of ion transport gi|134288912|ref|NP_001001985.3|/2.01151e-123/N-acetylaspartate synthetase [Mus musculus] 22715 2525.39 0.543333333 0.526666667 -0.044947406 Down 0.092923765 Zfp57 zinc finger protein 57 K09228|1|0.0|821|mmu:22715|KRAB domain-containing zinc finger protein GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin;GO:0000790//nuclear chromatin GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding GO:0007399//nervous system development;GO:0006306//DNA methylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007399//nervous system development;GO:0006306//DNA methylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007399//nervous system development;GO:0006306//DNA methylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007399//nervous system development;GO:0006306//DNA methylation;GO:0006366//transcription from RNA polymerase II promoter gi|62000700|ref|NP_001013767.1|/0/zinc finger protein 57 isoform 1 [Mus musculus] 108907 2861 0.553333333 0.57 0.042813084 Up 0.092923765 Nusap1 nucleolar and spindle associated protein 1 K11565|1|9e-22|108|mmu:70645|opa-interacting protein 5 GO:0031981//nuclear lumen;GO:0005819//spindle;GO:0031981//nuclear lumen;GO:0005819//spindle GO:0003676//nucleic acid binding;GO:0015631//tubulin binding;GO:0015631//tubulin binding GO:0007010//cytoskeleton organization;GO:0000087//mitotic M phase;GO:0007010//cytoskeleton organization;GO:0000087//mitotic M phase gi|111118996|ref|NP_001036117.1|/0/nucleolar and spindle-associated protein 1 isoform b [Mus musculus] 71567 3873 0.843333333 0.82 -0.040479069 Down 0.092923765 Mcm9 minichromosome maintenance 9 homologous recombination repair factor K10738|1|0.0|2020|mmu:71567|DNA helicase MCM9 [EC:3.6.4.12] GO:0043231//intracellular membrane-bounded organelle;GO:0042555//MCM complex GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0003676//nucleic acid binding GO:0007276//gamete generation;GO:0000725//recombinational repair gi|86439953|ref|NP_082106.2|/0/DNA helicase MCM9 [Mus musculus] 52850 3012 0.72 0.74 0.039528364 Up 0.092923765 Sgsm1 small G protein signaling modulator 1 K20168|1|3e-32|144|aag:AaeL_AAEL007848|TBC1 domain family member 15 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|828747244|ref|NP_001296455.1|/0/small G protein signaling modulator 1 isoform d [Mus musculus] 20688 9017 0.85 0.873333333 0.039069565 Up 0.092923765 Sp4 trans-acting transcription factor 4 K09194|1|0.0|981|mmu:20688|transcription factor Sp4 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity GO:0044057;GO:0006366//transcription from RNA polymerase II promoter;GO:0044057;GO:0006366//transcription from RNA polymerase II promoter "gi|148701533|gb|EDL33480.1|/0/trans-acting transcription factor 4, partial [Mus musculus]" 218820 4251 0.616666667 0.6 -0.039528364 Down 0.092923765 Zfp503 zinc finger protein 503 - - - - gi|33186868|ref|NP_663434.2|/0/zinc finger protein 503 [Mus musculus] 66775 2089 0.636666667 0.62 -0.038270017 Down 0.092923765 Hacd4 3-hydroxyacyl-CoA dehydratase 4 K10703|1|3e-123|445|mmu:66775|very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134] - - - - 212919 4266 0.756666667 0.736666667 -0.038645928 Down 0.092923765 Kctd7 potassium channel tetramerisation domain containing 7 K20131|1|1e-164|583|bacu:103015608|Rab5 GDP/GTP exchange factor GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0046914//transition metal ion binding GO:0051259//protein oligomerization gi|27369698|ref|NP_766097.1|/1.54112e-169/BTB/POZ domain-containing protein KCTD7 [Mus musculus] 269695 4398 0.896666667 0.92 0.037062094 Up 0.092923765 Rnft2 "ring finger protein, transmembrane 2" K10264|1|0.0|781|cfa:611303|F-box and WD-40 domain protein 8;K12838|2|4e-34|150|api:100160417|poly(U)-binding-splicing factor PUF60;K12012|3|2e-06|58.2|mze:106675796|tripartite motif-containing protein 35;K12031|4|5e-06|57.0|cfa:609505|tripartite motif-containing protein 65 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - "gi|148687849|gb|EDL19796.1|/0/transmembrane protein 118, isoform CRA_b [Mus musculus]" 66724 6381 0.686666667 0.666666667 -0.042644337 Down 0.092923765 Tab3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 K12793|1|0.0|1192|mmu:66724|TAK1-binding protein 3 - "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0046914//transition metal ion binding" GO:0006796//phosphate-containing compound metabolic process gi|60360252|dbj|BAD90370.1|/0/mKIAA4135 protein [Mus musculus] 22342 746 0.75 0.773333333 0.044199804 Up 0.092923765 Lin7b lin-7 homolog B (C. elegans) K19931|1|3e-102|373|mmu:22342|protein lin-7 GO:0043296//apical junction complex;GO:0044459;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane GO:0005515//protein binding GO:0016192//vesicle-mediated transport;GO:0045184//establishment of protein localization;GO:0001505//regulation of neurotransmitter levels;GO:0034329//cell junction assembly gi|6755971|ref|NP_035828.1|/2.35828e-101/protein lin-7 homolog B [Mus musculus] 66337 731 2.513333333 2.54 0.015226474 Up 0.092434841 Fam229b "family with sequence similarity 229, member B" - - - - gi|537235612|gb|ERE85265.1|/7.08644e-35/hypothetical protein H671_2g5373 [Cricetulus griseus] 74349 10873.01 2.02 2.053333333 0.023612557 Up 0.092434841 Fam160a2 "family with sequence similarity 160, member A2" - GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex;GO:0043234//protein complex - GO:0007041//lysosomal transport;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport;GO:0007033//vacuole organization;GO:0007041//lysosomal transport;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport;GO:0007033//vacuole organization;GO:0007041//lysosomal transport;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport;GO:0007033//vacuole organization;GO:0007041//lysosomal transport;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport;GO:0007033//vacuole organization gi|334358881|ref|NP_001229294.1|/0/FTS and Hook-interacting protein isoform c [Mus musculus] 269585 5446 2.636666667 2.603333333 -0.018355146 Down 0.092434841 Zscan20 zinc finger and SCAN domains 20 K09230|1|0.0|2133|mmu:269585|SCAN domain-containing zinc finger protein - - - gi|169234960|ref|NP_808426.2|/0/zinc finger and SCAN domain-containing protein 20 [Mus musculus] 380694 2709 1.646666667 1.673333333 0.023176322 Up 0.092434841 Ccnjl cyclin J-like K06627|1|5e-09|66.2|hmg:100206919|cyclin A;K13983|3|8e-09|65.5|dpe:Dper_GL13251|putative helicase MOV10L1 [EC:3.6.4.13];K05868|4|2e-07|60.8|crg:105326680|cyclin B GO:0043231//intracellular membrane-bounded organelle - - gi|113865891|ref|NP_001038995.1|/0/cyclin-J-like protein [Mus musculus] 57440 3658 2.333333333 2.363333333 0.018430705 Up 0.092434841 Ehd3 EH-domain containing 3 K12476|1|0.0|1004|mmu:57440|EH domain-containing protein 3 - - - - 338364 3050 2.123333333 2.156666667 0.02247234 Up 0.092434841 Trim65 tripartite motif-containing 65 K12031|1|0.0|906|mmu:338364|tripartite motif-containing protein 65 - - - gi|164518923|ref|NP_848917.2|/0/tripartite motif-containing protein 65 [Mus musculus] 67050 4262 2.256666667 2.226666667 -0.019307731 Down 0.092434841 Nkap NFKB activating protein K09229|1|4e-58|229|oas:105603790|KRAB and SCAN domains-containing zinc finger protein - - - - 68708 1650 2.253333333 2.226666667 -0.017175144 Down 0.092434841 Rabl2 "RAB, member RAS oncogene family-like 2" K07931|1|8e-123|443|mmu:68708|Rab-like protein 2 - - - "gi|148672384|gb|EDL04331.1|/4.27082e-137/RAB, member of RAS oncogene family-like 2A, isoform CRA_b [Mus musculus]" 11838 3056.06 1.996666667 1.97 -0.019397873 Down 0.092434841 Arc activity regulated cytoskeletal-associated protein K15867|1|0.0|823|mmu:11838|activity-regulated cytoskeleton-associated protein GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0031982//vesicle;GO:0044444//cytoplasmic part;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005856//cytoskeleton;GO:0031982//vesicle;GO:0044444//cytoplasmic part;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane GO:0005488//binding;GO:0005488//binding GO:0016192//vesicle-mediated transport;GO:0003002//regionalization;GO:0009888//tissue development;GO:0006996//organelle organization;GO:0048870//cell motility;GO:0000902//cell morphogenesis;GO:0007611//learning or memory;GO:0048167//regulation of synaptic plasticity;GO:0016192//vesicle-mediated transport;GO:0003002//regionalization;GO:0009888//tissue development;GO:0006996//organelle organization;GO:0048870//cell motility;GO:0000902//cell morphogenesis;GO:0007611//learning or memory;GO:0048167//regulation of synaptic plasticity gi|9055166|ref|NP_061260.1|/0/activity-regulated cytoskeleton-associated protein [Mus musculus] 100272219 1696 1.95 1.98 0.022026306 Up 0.092434841 AA543186 expressed sequence AA543186 - - - - gi|148676285|gb|EDL08232.1|/4.88709e-11/mCG1030131 [Mus musculus] 18393 3550.52 2.61 2.64 0.016488123 Up 0.092434841 Orc2 "origin recognition complex, subunit 2" K02604|1|0.0|1034|mmu:18393|origin recognition complex subunit 2 GO:0000808//origin recognition complex;GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0000777//condensed chromosome kinetochore;GO:0000808//origin recognition complex;GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0000777//condensed chromosome kinetochore;GO:0000808//origin recognition complex;GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0000777//condensed chromosome kinetochore GO:0043565//sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding GO:0006259//DNA metabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0051320;GO:0006366//transcription from RNA polymerase II promoter;GO:0006259//DNA metabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0051320;GO:0006366//transcription from RNA polymerase II promoter;GO:0006259//DNA metabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0051320;GO:0006366//transcription from RNA polymerase II promoter gi|70909306|ref|NP_001020549.1|/0/origin recognition complex subunit 2 isoform B [Mus musculus] 271981 6578 2.28 2.246666667 -0.021247734 Down 0.092434841 Tbck TBC1 domain containing kinase K17544|1|0.0|1757|mmu:271981|TBC domain-containing protein kinase-like protein GO:0044464 GO:0016301//kinase activity;GO:0032550 GO:0006464//cellular protein modification process gi|254553514|ref|NP_001156927.1|/0/TBC domain-containing protein kinase-like protein [Mus musculus] 83602 5691 2.936666667 2.903333333 -0.0164693 Down 0.092434841 Gtf2a1 "general transcription factor II A, 1" K03122|1|8e-110|402|mmu:83602|transcription initiation factor TFIIA large subunit GO:0005667//transcription factor complex;GO:0005667//transcription factor complex GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity;GO:0008134//transcription factor binding;GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity;GO:0008134//transcription factor binding GO:0006366//transcription from RNA polymerase II promoter;GO:0044764;GO:0006366//transcription from RNA polymerase II promoter "gi|148687003|gb|EDL18950.1|/7.12112e-109/general transcription factor II A, 1, isoform CRA_a, partial [Mus musculus]" 104001 1718.3 2.06 2.026666667 -0.023535514 Down 0.092434841 Rtn1 reticulon 1 K08288|1|1e-56|224|chx:102186405|protein kinase C substrate 80K-H;K09029|2|1e-07|62.0|fpg:101920606|protein FosB GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0060089;GO:0005488//binding;GO:0060089;GO:0005488//binding;GO:0060089;GO:0005488//binding GO:0030154//cell differentiation;GO:0030154//cell differentiation;GO:0007154//cell communication;GO:0030154//cell differentiation;GO:0007154//cell communication;GO:0030154//cell differentiation;GO:0007154//cell communication "gi|148704589|gb|EDL36536.1|/0/reticulon 1, isoform CRA_b, partial [Mus musculus]" 270627 8033 2.13 2.16 0.020177882 Up 0.092434841 Taf1 TATA-box binding protein associated factor 1 K03125|1|0.0|3142|mmu:270627|transcription initiation factor TFIID subunit 1 GO:0044665//MLL1/2 complex;GO:0005667//transcription factor complex GO:0042393//histone binding;GO:0032550;GO:0003712//transcription cofactor activity;GO:0004672//protein kinase activity;GO:0003676//nucleic acid binding;GO:0008134//transcription factor binding;GO:0008080//N-acetyltransferase activity GO:0006366//transcription from RNA polymerase II promoter;GO:0016570//histone modification;GO:0051318;GO:0006468//protein phosphorylation;GO:0031331 gi|595582247|ref|NP_001277658.1|/0/transcription initiation factor TFIID subunit 1 [Mus musculus] 64933 3405 1.693333333 1.72 0.022542569 Up 0.092434841 Ap3m2 "adaptor-related protein complex 3, mu 2 subunit" K12398|1|0.0|818|mmu:64933|AP-3 complex subunit mu GO:0030119//AP-type membrane coat adaptor complex;GO:0012506//vesicle membrane;GO:0030119//AP-type membrane coat adaptor complex;GO:0012506//vesicle membrane - GO:0008088//axo-dendritic transport;GO:0048489//synaptic vesicle transport;GO:0001505//regulation of neurotransmitter levels;GO:0015031//protein transport;GO:0008088//axo-dendritic transport;GO:0048489//synaptic vesicle transport;GO:0001505//regulation of neurotransmitter levels;GO:0015031//protein transport gi|537273592|gb|ERE92476.1|/0/AP-3 complex subunit mu-2 [Cricetulus griseus] 71609 1385 2.406666667 2.376666667 -0.01809676 Down 0.092434841 Tradd TNFRSF1A-associated via death domain K03171|1|6e-153|543|mmu:71609|tumor necrosis factor receptor type 1-associated DEATH domain protein GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043232;GO:0044425 GO:0019899//enzyme binding;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0019904//protein domain specific binding GO:0012502//induction of programmed cell death;GO:0051259//protein oligomerization;GO:0006915//apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0001942//hair follicle development;GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|75677522|ref|NP_001028333.1|/4.8231e-152/tumor necrosis factor receptor type 1-associated DEATH domain protein [Mus musculus] 622283 2019 1.806666667 1.833333333 0.021138767 Up 0.092434841 Gm6307 Mir1a-1 and Mir133a-2 host gene - - - - "gi|148675219|gb|EDL07166.1|/2.25001e-13/mCG1028420, partial [Mus musculus]" 72033 8829 2.746666667 2.78 0.017403046 Up 0.092434841 Tsc22d2 "TSC22 domain family, member 2" - - - - gi|148703386|gb|EDL35333.1|/1.41104e-135/mCG8104 [Mus musculus] 246694 4729 1.81 1.836666667 0.021100121 Up 0.092434841 Hps5 Hermansky-Pudlak syndrome 5 K20191|1|0.0|2041|mmu:246694|Hermansky-Pudlak syndrome 5 protein - - - - 18715 2054 2.31 2.336666667 0.016559092 Up 0.092434841 Pim2 proviral integration site 2 K08806|1|0.0|637|mmu:18715|proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1] - GO:0032550;GO:0004672//protein kinase activity "GO:0006351//transcription, DNA-templated;GO:0031647//regulation of protein stability;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0006796//phosphate-containing compound metabolic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006464//cellular protein modification process;GO:0006914//autophagy" gi|765067|gb|AAA98923.1|/4.13435e-180/protein-serine/threonine kinase [Mus musculus] 378466 1651.91 2.343333333 2.37 0.016324871 Up 0.092434841 Gm10033 predicted gene 10033 - - - - - 20449 8995 0.066666667 0.073333333 0.137503524 Up 0.092406634 St8sia1 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1" "K03371|1|0.0|739|mmu:20449|alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8A) [EC:2.4.99.8]" GO:0031228//intrinsic component of Golgi membrane GO:0008373//sialyltransferase activity GO:0006687//glycosphingolipid metabolic process;GO:0009408//response to heat;GO:0006464//cellular protein modification process;GO:0008283//cell proliferation "gi|70980543|ref|NP_035504.2|/0/alpha-N-acetylneuraminide alpha-2,8-sialyltransferase [Mus musculus]" 22349 3117 0.07 0.063333333 -0.144389909 Down 0.092406634 Vil1 villin 1 K05761|1|0.0|1599|mmu:22349|villin 1 GO:0015629//actin cytoskeleton;GO:0030175//filopodium;GO:0031252//cell leading edge GO:0036041//long-chain fatty acid binding;GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0004869//cysteine-type endopeptidase inhibitor activity GO:0035728//response to hepatocyte growth factor;GO:0022604//regulation of cell morphogenesis;GO:0010631//epithelial cell migration;GO:0038127//ERBB signaling pathway;GO:0030835//negative regulation of actin filament depolymerization;GO:0051017//actin filament bundle assembly;GO:0051707//response to other organism;GO:0006915//apoptotic process;GO:0042060//wound healing;GO:0070849//response to epidermal growth factor gi|755492322|ref|XP_011236780.1|/0/PREDICTED: villin-1 isoform X1 [Mus musculus] 18406 774 0.07 0.063333333 -0.144389909 Down 0.092406634 Orm2 orosomucoid 2 K17308|1|1e-83|311|mmu:18405|alpha-1-acid glycoprotein 1 GO:0044421 GO:0005488//binding GO:0002526//acute inflammatory response;GO:0002437//inflammatory response to antigenic stimulus;GO:0060416//response to growth hormone;GO:0009887//organ morphogenesis;GO:0051384//response to glucocorticoid;GO:0002237//response to molecule of bacterial origin;GO:0032526//response to retinoic acid;GO:0051234//establishment of localization gi|6754950|ref|NP_035146.1|/1.68847e-105/alpha-1-acid glycoprotein 2 precursor [Mus musculus] 106059 4356.13 0.1 0.11 0.137503524 Up 0.092406634 A430088P11Rik RIKEN cDNA A430088P11 gene - - - - - 75571 1053 0.143333333 0.13 -0.140862536 Down 0.092406634 Spata9 spermatogenesis associated 9 K08766|1|2e-25|118|amj:102569149|carnitine O-palmitoyltransferase 2 [EC:2.3.1.21] GO:0031224//intrinsic component of membrane - GO:0048232//male gamete generation;GO:0048869//cellular developmental process gi|21735467|ref|NP_083619.1|/4.63536e-135/spermatogenesis-associated protein 9 [Mus musculus] 109280 1455 0.073333333 0.066666667 -0.137503524 Down 0.092406634 Slc22a13b-ps "solute carrier family 22 (organic cation transporter), member 13b, pseudogene" "K08209|1|2e-106|388|mmu:102570|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 13" GO:0031224//intrinsic component of membrane GO:0005215//transporter activity - "gi|148677285|gb|EDL09232.1|/8.63546e-123/mCG21878, isoform CRA_c, partial [Mus musculus]" 14255 3664 0.106666667 0.096666667 -0.142019005 Down 0.092406634 Flt3 FMS-like tyrosine kinase 3 K05092|1|0.0|2007|mmu:14255|fms-related tyrosine kinase 3 [EC:2.7.10.1] GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0035258//steroid hormone receptor binding;GO:0004888//transmembrane signaling receptor activity GO:0030183//B cell differentiation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0034097//response to cytokine;GO:0006468//protein phosphorylation;GO:0002320//lymphoid progenitor cell differentiation;GO:0032943//mononuclear cell proliferation "gi|148673886|gb|EDL05833.1|/0/FMS-like tyrosine kinase 3, isoform CRA_b, partial [Mus musculus]" 209540 4142 0.07 0.063333333 -0.144389909 Down 0.092406634 Rgag1 retrotransposon gag domain containing 1 K13908|1|2e-30|138|ngi:103751114|mucin-5B - - - gi|590122005|ref|NP_001035524.2|/0/retrotransposon gag domain-containing protein 1 [Mus musculus] 77779 2317 0.106666667 0.096666667 -0.142019005 Down 0.092406634 A930007I19Rik RIKEN cDNA A930007I19 gene - - - - - 74521 3683 0.066666667 0.073333333 0.137503524 Up 0.092406634 Ppp4r4 "protein phosphatase 4, regulatory subunit 4" K15426|1|0.0|1654|mmu:74521|serine/threonine-protein phosphatase 4 regulatory subunit 4 GO:0043234//protein complex;GO:0044424 GO:0005488//binding;GO:0019208//phosphatase regulator activity GO:0010923//negative regulation of phosphatase activity;GO:0043666//regulation of phosphoprotein phosphatase activity "gi|148686877|gb|EDL18824.1|/0/RIKEN cDNA 8430415E04, isoform CRA_a, partial [Mus musculus]" 93881 2842 0.073333333 0.066666667 -0.137503524 Down 0.092406634 Pcdhb10 protocadherin beta 10 K16494|1|0.0|1509|mmu:93881|protocadherin beta GO:0031224//intrinsic component of membrane - GO:0022610 gi|18087783|ref|NP_444365.1|/0/protocadherin beta 10 precursor [Mus musculus] 242505 5183 0.143333333 0.13 -0.140862536 Down 0.092406634 Rasef RAS and EF hand domain containing K17199|1|0.0|1187|mmu:242505|Ras and EF-hand domain-containing protein GO:0044424 GO:0046872//metal ion binding;GO:0032550 GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization gi|62945396|ref|NP_001017427.1|/0/ras and EF-hand domain-containing protein homolog [Mus musculus] 170741 1020 0.126666667 0.14 0.144389909 Up 0.092406634 Pilrb1 paired immunoglobin-like type 2 receptor beta 1 K15411|1|7e-86|319|mmu:231805|paired immunoglobulin-like type 2 receptor alpha GO:0031224//intrinsic component of membrane GO:0042287//MHC protein binding GO:0002762//negative regulation of myeloid leukocyte differentiation gi|755514600|ref|XP_011239235.1|/2.96823e-147/PREDICTED: paired immunoglobulin-like type 2 receptor beta isoform X1 [Mus musculus] 17381 3607 0.1 0.11 0.137503524 Up 0.092406634 Mmp12 matrix metallopeptidase 12 K01413|1|0.0|880|mmu:17381|matrix metalloproteinase-12 (macrophage elastase) [EC:3.4.24.65] GO:0031012//extracellular matrix;GO:0031012//extracellular matrix;GO:0031012//extracellular matrix "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides;GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" "GO:0019538//protein metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0044319//wound healing, spreading of cells;GO:0042221//response to chemical;GO:0019538//protein metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0044319//wound healing, spreading of cells;GO:0042221//response to chemical;GO:0019538//protein metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0044319//wound healing, spreading of cells;GO:0042221//response to chemical" gi|74213223|dbj|BAE41743.1|/0/unnamed protein product [Mus musculus] 73297 2345 0.096666667 0.106666667 0.142019005 Up 0.092406634 1700034I23Rik FUN14 domain containing 2 pseudogene K17986|1|9e-46|187|clv:102091908|FUN14 domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle - - gi|109730699|gb|AAI17740.1|/3.13189e-86/RIKEN cDNA 1700034I23 gene [Mus musculus] 69566 1547 0.126666667 0.14 0.144389909 Up 0.092406634 2310016D03Rik RIKEN cDNA 2310016D03 gene - - - - - 22390 3419 6.453333333 6.503333333 0.011134825 Up 0.092199782 Wee1 WEE 1 homolog 1 (S. pombe) K06632|1|0.0|1126|mmu:22390|wee1-like protein kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0046872//metal ion binding;GO:0004713//protein tyrosine kinase activity GO:0006468//protein phosphorylation;GO:0007163//establishment or maintenance of cell polarity;GO:0031175//neuron projection development;GO:0007010//cytoskeleton organization;GO:0000087//mitotic M phase gi|31543956|ref|NP_033542.2|/0/wee1-like protein kinase [Mus musculus] 11877 4489.82 6.206666667 6.256666667 0.011575577 Up 0.092199782 Arvcf armadillo repeat gene deleted in velo-cardio-facial syndrome "K05690|1|0.0|726|aam:106489138|catenin (cadherin-associated protein), delta 1" GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0016337//single organismal cell-cell adhesion;GO:0016337//single organismal cell-cell adhesion;GO:0016337//single organismal cell-cell adhesion;GO:0016337//single organismal cell-cell adhesion;GO:0016337//single organismal cell-cell adhesion;GO:0016337//single organismal cell-cell adhesion gi|433809348|ref|NP_001258960.1|/0/armadillo repeat protein deleted in velo-cardio-facial syndrome homolog isoform 3 [Mus musculus] 71711 2004 12.17666667 12.13 -0.005539703 Down 0.092199782 Mus81 MUS81 structure-specific endonuclease subunit K08991|1|0.0|1073|mmu:71711|crossover junction endonuclease MUS81 [EC:3.1.22.-] GO:0031981//nuclear lumen "GO:0043169//cation binding;GO:0016889//endodeoxyribonuclease activity, producing 3'-phosphomonoesters" GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress gi|170016083|ref|NP_082153.3|/0/crossover junction endonuclease MUS81 [Mus musculus] 213326 3429.48 5.263333333 5.31 0.012735096 Up 0.092199782 Scyl2 SCY1-like 2 (S. cerevisiae) K17541|1|0.0|1687|mmu:213326|SCY1-like protein 2 - - - - 66607 1480 8.17 8.216666667 0.008217162 Up 0.092199782 Ms4a4d "membrane-spanning 4-domains, subfamily A, member 4D" "K19928|1|8e-12|74.3|clv:102089886|zona pellucida sperm-binding protein 3;K06466|4|1e-06|57.0|ecb:100059000|membrane-spanning 4-domains, subfamily A, member 1" GO:0031224//intrinsic component of membrane - - "gi|148709484|gb|EDL41430.1|/1.3637e-123/mCG12900, partial [Mus musculus]" 68770 4839 11.48 11.43333333 -0.005876566 Down 0.092199782 Phtf2 putative homeodomain transcription factor 2 - GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" "gi|148671275|gb|EDL03222.1|/0/putative homeodomain transcription factor 2, isoform CRA_a [Mus musculus]" 214669 3370.64 5.133333333 5.086666667 -0.013175389 Down 0.092199782 L3mbtl2 l(3)mbt-like 2 (Drosophila) K11465|1|7e-31|138|tup:102500909|sex comb on midleg-like protein 2;K11461|5|3e-30|136|bfo:BRAFLDRAFT_273612|polycomb protein SCMH1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0042393//histone binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0046872//metal ion binding;GO:0042393//histone binding;GO:0046914//transition metal ion binding;GO:0042393//histone binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" "gi|148672621|gb|EDL04568.1|/0/l(3)mbt-like 2 (Drosophila), isoform CRA_d, partial [Mus musculus]" 234135 5696.69 5.996666667 5.946666667 -0.012079571 Down 0.092199782 Whsc1l1 Wolf-Hirschhorn syndrome candidate 1-like 1 (human) K11425|1|0.0|2619|cge:100773097|histone-lysine N-methyltransferase NSD3 [EC:2.1.1.43] GO:0043232 GO:0046914//transition metal ion binding;GO:0016279//protein-lysine N-methyltransferase activity "GO:0006351//transcription, DNA-templated;GO:0016571//histone methylation" gi|48958537|ref|NP_001001735.1|/0/histone-lysine N-methyltransferase NSD3 isoform 1 [Mus musculus] 269593 7529 5.946666667 5.896666667 -0.012181567 Down 0.092199782 Luzp1 leucine zipper protein 1 K10352|1|3e-10|72.0|lcm:102355626|myosin heavy chain;K17751|2|4e-10|71.2|gja:107118586|myosin heavy chain 6/7;K12478|5|3e-09|68.6|ola:101175647|early endosome antigen 1 GO:0043231//intracellular membrane-bounded organelle - GO:0001842//neural fold formation;GO:0001568//blood vessel development;GO:0003231//cardiac ventricle development gi|119433663|ref|NP_077772.2|/0/leucine zipper protein 1 [Mus musculus] 69237 2579 10.28 10.23 -0.007034119 Down 0.092199782 Gtpbp4 GTP binding protein 4 K06943|1|0.0|1043|mmu:69237|nucleolar GTP-binding protein GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0032091//negative regulation of protein binding;GO:0031647//regulation of protein stability;GO:0022613//ribonucleoprotein complex biogenesis;GO:0008283//cell proliferation;GO:0007162//negative regulation of cell adhesion;GO:0016567//protein ubiquitination;GO:0009154//purine ribonucleotide catabolic process;GO:0016477//cell migration;GO:0006260//DNA replication gi|31560110|ref|NP_081276.2|/0/nucleolar GTP-binding protein 1 [Mus musculus] 51885 4278 5.846666667 5.896666667 0.0122853 Up 0.092199782 Tubgcp4 "tubulin, gamma complex associated protein 4" K16571|1|0.0|1215|mmu:51885|gamma-tubulin complex component 4 GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005815//microtubule organizing center;GO:0005819//spindle - - "gi|148696094|gb|EDL28041.1|/0/DNA segment, Chr 2, ERATO Doi 435, expressed, isoform CRA_c, partial [Mus musculus]" 263876 3996 5.47 5.416666667 -0.014135521 Down 0.092199782 Spata2 spermatogenesis associated 2 K17595|1|0.0|928|mmu:263876|spermatogenesis-associated protein 2 GO:0044424 - - "gi|148674567|gb|EDL06514.1|/0/spermatogenesis associated 2, partial [Mus musculus]" 16518 5468 8.66 8.613333333 -0.007795361 Down 0.092199782 Kcnj2 "potassium inwardly-rectifying channel, subfamily J, member 2" K04996|1|0.0|867|mmu:16518|potassium inwardly-rectifying channel subfamily J member 2 GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0044297//cell body GO:0005249//voltage-gated potassium channel activity;GO:0005515//protein binding GO:0001508//action potential;GO:0070838//divalent metal ion transport;GO:0034220//ion transmembrane transport gi|431908827|gb|ELK12419.1|/0/Inward rectifier potassium channel 2 [Pteropus alecto] 67920 1857 6.82 6.873333333 0.011238188 Up 0.092199782 Mak16 MAK16 homolog K14831|1|9e-113|410|mmu:67920|protein MAK16 - - - gi|148700830|gb|EDL32777.1|/7.25626e-112/RNA binding motif protein 13 [Mus musculus] 71713 3370 7.493333333 7.543333333 0.009594549 Up 0.092199782 Cdc40 cell division cycle 40 K12816|1|0.0|1089|mmu:71713|pre-mRNA-processing factor 17 - - - - 72193 7724 6.603333333 6.653333333 0.01088284 Up 0.092199782 Scaf11 SR-related CTD-associated factor 11 K17586|1|5e-25|120|cjc:100410983|PHD and RING finger domain-containing protein 1 - - - "gi|148672294|gb|EDL04241.1|/0/splicing factor, arginine/serine-rich 2, interacting protein, isoform CRA_a, partial [Mus musculus]" 218793 1410 6.07 6.12 0.011835136 Up 0.092199782 Ube2e2 ubiquitin-conjugating enzyme E2E 2 K20217|1|9e-96|353|cge:100766861|ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23] - GO:0019787//ubiquitin-like protein transferase activity;GO:0032550 GO:0000209//protein polyubiquitination gi|568985412|ref|XP_006518073.1|/2.50237e-95/PREDICTED: ubiquitin-conjugating enzyme E2 E2 isoform X2 [Mus musculus] 71997 2232 5.33 5.28 -0.013597603 Down 0.092199782 Smg9 "smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)" K18735|1|0.0|882|mmu:71997|protein SMG9 GO:0044464 GO:0005515//protein binding GO:0000956//nuclear-transcribed mRNA catabolic process gi|21312548|ref|NP_082323.1|/0/protein SMG9 [Mus musculus] 13486 3080 6.69 6.636666667 -0.011547396 Down 0.092199782 Dr1 down-regulator of transcription 1 K08065|1|3e-12|77.0|xtr:100135753|nuclear transcription Y subunit beta GO:0000123//histone acetyltransferase complex GO:0003712//transcription cofactor activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity;GO:0008134//transcription factor binding GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter gi|149709587|ref|XP_001491698.1|/1.03239e-55/PREDICTED: protein Dr1 [Equus caballus] 67630 6997 10.19666667 10.14666667 -0.007091748 Down 0.092199782 Samd8 sterile alpha motif domain containing 8 K04714|1|3e-87|327|bfo:BRAFLDRAFT_104157|shingomyelin synthase [EC:2.7.8.27] GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0003824//catalytic activity GO:0006684//sphingomyelin metabolic process;GO:0046513//ceramide biosynthetic process gi|21312864|ref|NP_080559.1|/0/sphingomyelin synthase-related protein 1 [Mus musculus] 320184 8592 7.76 7.806666667 0.008650018 Up 0.092199782 Lrrc58 leucine rich repeat containing 58 K05692|1|5e-158|233|umr:103665813|actin beta/gamma 1 - - - "gi|671002440|ref|XP_008692076.1|/4.32543e-157/PREDICTED: LOW QUALITY PROTEIN: actin, cytoplasmic 2 [Ursus maritimus]" 19821 3028 5.063333333 5.013333333 -0.014317303 Down 0.092199782 Rnf2 ring finger protein 2 K10695|1|0.0|675|mmu:19821|E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27] GO:0044665//MLL1/2 complex;GO:0031519//PcG protein complex;GO:0000803//sex chromosome GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding;GO:0019787//ubiquitin-like protein transferase activity GO:0010390//histone monoubiquitination;GO:0007369//gastrulation;GO:0006366//transcription from RNA polymerase II promoter;GO:0009798//axis specification;GO:0007049//cell cycle "gi|148707518|gb|EDL39465.1|/0/ring finger protein 2, isoform CRA_a, partial [Mus musculus]" 212442 1889 10.73666667 10.78333333 0.006257051 Up 0.092199782 Lactb2 "lactamase, beta 2" K17725|1|1e-07|60.8|hro:HELRODRAFT_115427|sulfur dioxygenase [EC:1.13.11.18];K01069|2|6e-07|58.5|ame:552568|hydroxyacylglutathione hydrolase [EC:3.1.2.6] GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity;GO:0043169//cation binding - gi|21703764|ref|NP_663356.1|/9.85406e-165/beta-lactamase-like protein 2 [Mus musculus] 75221 2683 10.42 10.47 0.006906165 Up 0.092199782 Dpp3 dipeptidylpeptidase 3 K01277|1|0.0|1471|mmu:75221|dipeptidyl-peptidase III [EC:3.4.14.4] GO:0016020//membrane;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity GO:0019538//protein metabolic process gi|244791124|ref|NP_598564.2|/0/dipeptidyl peptidase 3 [Mus musculus] 114585 2126 11.68 11.73 0.006162739 Up 0.092199782 D17H6S53E "DNA segment, Chr 17, human D6S53E" - - - - gi|51591905|ref|NP_258438.1|/1.48832e-156/uncharacterized protein C6orf47 homolog [Mus musculus] 234875 3049 5.956666667 5.903333333 -0.012975422 Down 0.092199782 Ttc13 tetratricopeptide repeat domain 13 K09667|1|7e-07|59.3|hgl:101710902|protein O-GlcNAc transferase [EC:2.4.1.255] - - - gi|124249339|ref|NP_663582.2|/0/tetratricopeptide repeat protein 13 precursor [Mus musculus] 67972 7130 4.913333333 4.963333333 0.014607229 Up 0.092199782 Atp2b1 "ATPase, Ca++ transporting, plasma membrane 1" "K05850|1|0.0|2206|mmu:67972|Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]" GO:0016021//integral component of membrane;GO:0032589//neuron projection membrane;GO:0043025//neuronal cell body GO:0043169//cation binding;GO:0032550;GO:0008324//cation transmembrane transporter activity;GO:0019904//protein domain specific binding;GO:0003824//catalytic activity GO:0044763;GO:0007599//hemostasis;GO:0070838//divalent metal ion transport gi|62234487|ref|NP_080758.1|/0/plasma membrane calcium-transporting ATPase 1 [Mus musculus] 52588 2598.92 7.566666667 7.62 0.010133106 Up 0.092199782 Tspan14 tetraspanin 14 K17296|1|3e-142|508|cge:100758665|tetraspanin-14 - - - - 73178 4348 9.156666667 9.106666667 -0.007899427 Down 0.092199782 Wasl Wiskott-Aldrich syndrome-like (human) K05747|1|6e-147|525|mmu:73178|Wiskott-Aldrich syndrome protein GO:0043231//intracellular membrane-bounded organelle;GO:0031252//cell leading edge;GO:0030864//cortical actin cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0031252//cell leading edge;GO:0030864//cortical actin cytoskeleton GO:0030695//GTPase regulator activity;GO:0008092//cytoskeletal protein binding;GO:0030695//GTPase regulator activity;GO:0008092//cytoskeletal protein binding "GO:0031503//protein complex localization;GO:0006351//transcription, DNA-templated;GO:0051707//response to other organism;GO:0007009//plasma membrane organization;GO:0031346//positive regulation of cell projection organization;GO:0007015//actin filament organization;GO:0065003;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0022402//cell cycle process;GO:0031503//protein complex localization;GO:0006351//transcription, DNA-templated;GO:0051707//response to other organism;GO:0007009//plasma membrane organization;GO:0031346//positive regulation of cell projection organization;GO:0007015//actin filament organization;GO:0065003;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0022402//cell cycle process" gi|268370042|ref|NP_001161217.1|/2.30535e-108/neural Wiskott-Aldrich syndrome protein isoform 2 [Mus musculus] 67446 1491 8.36 8.406666667 0.008030928 Up 0.092199782 Dusp28 dual specificity phosphatase 28 K14165|1|2e-80|302|mmu:67446|atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] - - - gi|29171320|ref|NP_780327.1|/1.59667e-79/dual specificity phosphatase 28 [Mus musculus] 93871 4219.59 7.856666667 7.906666667 0.009152251 Up 0.092199782 Brwd1 bromodomain and WD repeat domain containing 1 K11798|1|4e-53|212|ssc:100625737|bromodomain and WD repeat domain containing protein 1/3 GO:0031981//nuclear lumen - GO:0006996//organelle organization;GO:0022604//regulation of cell morphogenesis;GO:0006366//transcription from RNA polymerase II promoter gi|157057182|ref|NP_001096649.1|/0/bromodomain and WD repeat-containing protein 1 isoform B [Mus musculus] 50789 4265 10.92333333 10.97666667 0.007026839 Up 0.092199782 Fbxl3 F-box and leucine-rich repeat protein 3 K10269|1|0.0|848|mmu:50789|F-box and leucine-rich repeat protein 3 GO:0031461//cullin-RING ubiquitin ligase complex;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0019787//ubiquitin-like protein transferase activity GO:0007623//circadian rhythm;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process gi|6456096|gb|AAF09131.1|/0/leucine-rich repeat-containing F-box protein FBL3a [Mus musculus] 319880 5493.89 12.28666667 12.24 -0.005490012 Down 0.092199782 Tmcc3 transmembrane and coiled coil domains 3 K16288|1|9e-95|352|oaa:100076390|receptor-interacting serine/threonine-protein kinase 5 [EC:2.7.11.1] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148689636|gb|EDL21583.1|/0/transmembrane and coiled coil domains 3, isoform CRA_c [Mus musculus]" 69608 3881 12.31666667 12.27 -0.005476615 Down 0.092199782 Sec24d "Sec24 related gene family, member D (S. cerevisiae)" K14007|1|0.0|1793|mmu:69608|protein transport protein SEC24 - - GO:0045184//establishment of protein localization gi|46560565|ref|NP_081411.2|/0/protein transport protein Sec24D [Mus musculus] 70024 3510 0.116666667 0.106666667 -0.129283017 Down 0.091814284 Mcm10 minichromosome maintenance 10 replication initiation factor K10736|1|0.0|1509|mmu:70024|minichromosome maintenance protein 10 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0003676//nucleic acid binding;GO:0043169//cation binding;GO:0003676//nucleic acid binding GO:0006259//DNA metabolic process;GO:0006259//DNA metabolic process gi|755496861|ref|XP_006497595.2|/0/PREDICTED: protein MCM10 homolog isoform X2 [Mus musculus] 17183 2243 0.153333333 0.14 -0.131244533 Down 0.091814284 Matn4 matrilin 4 K19467|1|4e-91|338|cfa:482985|matrilin-3 - - GO:0009611//response to wounding;GO:0009611//response to wounding gi|224967060|ref|NP_038620.2|/0/matrilin-4 precursor [Mus musculus] 231238 4532 0.12 0.11 -0.125530882 Down 0.091814284 Sel1l3 sel-1 suppressor of lin-12-like 3 (C. elegans) K14026|1|4e-34|150|crg:105345138|SEL1 protein GO:0031224//intrinsic component of membrane - - gi|28972381|dbj|BAC65644.1|/0/mKIAA0746 protein [Mus musculus] 18988 2522 0.116666667 0.106666667 -0.129283017 Down 0.091814284 Pou2f3 "POU domain, class 2, transcription factor 3" "K09364|1|5e-180|634|mmu:18988|POU domain transcription factor, class 2" GO:0031981//nuclear lumen;GO:0043234//protein complex GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0009611//response to wounding;GO:0006366//transcription from RNA polymerase II promoter;GO:0009913//epidermal cell differentiation;GO:0032897//negative regulation of viral transcription "gi|119226249|ref|NP_035269.2|/4.48277e-179/POU domain, class 2, transcription factor 3 [Mus musculus]" 171209 1830 0.16 0.146666667 -0.125530882 Down 0.091814284 Asic3 acid-sensing (proton-gated) ion channel 3 K04830|1|0.0|1056|mmu:171209|acid-sensing ion channel 3 GO:0016021//integral component of membrane;GO:0044424 GO:0042927;GO:0019904//protein domain specific binding;GO:0005272//sodium channel activity GO:0006814//sodium ion transport;GO:0007606//sensory perception of chemical stimulus;GO:0050954//sensory perception of mechanical stimulus;GO:0019233//sensory perception of pain;GO:0042221//response to chemical;GO:0016048//detection of temperature stimulus;GO:0006950//response to stress gi|882939029|ref|NP_001297403.1|/0/acid-sensing ion channel 3 isoform 2 [Mus musculus] 73332 2723 0.14 0.153333333 0.131244533 Up 0.091814284 Ccdc30 coiled-coil domain containing 30 K16464|1|3e-14|84.0|lcm:102351703|centrosomal protein CEP250;K20478|2|5e-14|83.2|dre:557772|golgin subfamily B member 1 - - - gi|117676405|ref|NP_083562.1|/0/coiled-coil domain-containing protein 30 isoform a [Mus musculus] 239436 1906 0.07 0.076666667 0.131244533 Up 0.091814284 Slc30a8 "solute carrier family 30 (zinc transporter), member 8" "K14695|1|0.0|685|mmu:239436|solute carrier family 30 (zinc transporter), member 8" "GO:0031224//intrinsic component of membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle" GO:0042802//identical protein binding;GO:0015075//ion transmembrane transporter activity GO:0016192//vesicle-mediated transport;GO:0050796//regulation of insulin secretion;GO:0006829//zinc II ion transport;GO:0009746;GO:0032119//sequestering of zinc ion;GO:0033500//carbohydrate homeostasis gi|27370218|ref|NP_766404.1|/0/zinc transporter 8 [Mus musculus] 241128 2862 0.103333333 0.113333333 0.133266531 Up 0.091814284 Fam124b "family with sequence similarity 124, member B" - - - - gi|27734128|ref|NP_775601.1|/0/protein FAM124B [Mus musculus] 100039027 794 0.136666667 0.15 0.134301092 Up 0.091814284 Gm2011 predicted gene 2011 - - - - gi|12844839|dbj|BAB26518.1|/1.02037e-84/unnamed protein product [Mus musculus] 14012 3216 0.14 0.153333333 0.131244533 Up 0.091814284 Mpzl2 myelin protein zero-like 2 K06770|1|4e-23|113|xma:102233566|myelin protein zero GO:0031224//intrinsic component of membrane - GO:0030217//T cell differentiation;GO:0007155//cell adhesion gi|31542623|ref|NP_031988.2|/4.64899e-107/myelin protein zero-like protein 2 precursor [Mus musculus] 102423 2100 0.87 0.89 0.032789935 Up 0.091551017 Hinfp histone H4 transcription factor K09228|1|2e-29|133|lgi:LOTGIDRAFT_168313|KRAB domain-containing zinc finger protein GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding "GO:0006351//transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0006259//DNA metabolic process;GO:0043009//chordate embryonic development;GO:0008104//protein localization;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042692//muscle cell differentiation" gi|568958620|ref|XP_006509960.1|/0/PREDICTED: histone H4 transcription factor isoform X4 [Mus musculus] 12479 1845 1.146666667 1.17 0.029062466 Up 0.091551017 Cd1d1 CD1d1 antigen K06448|1|0.0|656|mmu:12479|CD1 antigen GO:0000323//lytic vacuole;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0005768//endosome GO:0030882//lipid antigen binding;GO:0005102//receptor binding GO:0001865//NK T cell differentiation;GO:0046635//positive regulation of alpha-beta T cell activation;GO:0019884//antigen processing and presentation of exogenous antigen;GO:0042097;GO:0042095//interferon-gamma biosynthetic process;GO:0042094//interleukin-2 biosynthetic process;GO:0043368//positive T cell selection;GO:0019883//antigen processing and presentation of endogenous antigen;GO:0006952//defense response;GO:0042098//T cell proliferation gi|161484595|ref|NP_031665.2|/0/antigen-presenting glycoprotein CD1d1 precursor [Mus musculus] 70640 8643 1.026666667 1.006666667 -0.028381801 Down 0.091551017 Dcp2 decapping mRNA 2 K12613|1|0.0|810|mmu:70640|mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] - - - - 246747 665 1.09 1.07 -0.026717338 Down 0.091551017 Adig adipogenin - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0045444//fat cell differentiation "gi|148674324|gb|EDL06271.1|/1.62737e-49/cDNA sequence BC054059, isoform CRA_b, partial [Mus musculus]" 319493 2970 1.033333333 1.01 -0.032950422 Down 0.091551017 A430078G23Rik RIKEN cDNA A430078G23 gene "K04257|1|7e-11|72.4|mmu:259023|olfactory receptor;K06751|2|7e-11|72.4|mmu:100529082|major histocompatibility complex, class I" - - - gi|283837884|ref|NP_001028550.2|/0/uncharacterized protein LOC319493 [Mus musculus] 74190 3276 1.046666667 1.026666667 -0.027834208 Down 0.091551017 Exoc3l4 exocyst complex component 3-like 4 K06110|1|9e-58|228|lcm:102360701|exocyst complex component 3;K19988|3|4e-33|146|mmu:74463|exocyst complex component 3-like protein 2 - - GO:0016192//vesicle-mediated transport;GO:0016192//vesicle-mediated transport;GO:0016192//vesicle-mediated transport;GO:0016192//vesicle-mediated transport "gi|148686688|gb|EDL18635.1|/0/RIKEN cDNA 1200009I06, isoform CRA_b, partial [Mus musculus]" 72507 4879.45 1.216666667 1.24 0.027406157 Up 0.091551017 Dzip1l DAZ interacting protein 1-like K16470|1|0.0|1249|mmu:72507|zinc finger protein DZIP1 GO:0005813//centrosome;GO:0005813//centrosome GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0010927;GO:0010927 gi|568962130|ref|XP_006511535.1|/0/PREDICTED: zinc finger protein DZIP1L isoform X2 [Mus musculus] 213332 781 0.92 0.936666667 0.025901863 Up 0.091551017 Mfsd4b4 major facilitator superfamily domain containing 4B4 "K08175|1|3e-89|330|rno:499462|MFS transporter, FHS family, Na+ dependent glucose transporter 1" - - - - 100978 3671 1.066666667 1.086666667 0.026800059 Up 0.091551017 Nfxl1 "nuclear transcription factor, X-box binding-like 1" K15683|1|0.0|1744|mmu:100978|NF-X1-type zinc finger protein NFXL1 - - - gi|124301201|ref|NP_598682.2|/0/NF-X1-type zinc finger protein NFXL1 [Mus musculus] 50524 4771 0.943333333 0.923333333 -0.030916077 Down 0.091551017 Sall2 sal-like 2 (Drosophila) K19871|1|0.0|1565|mmu:50524|sal-like protein GO:0000118//histone deacetylase complex GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding "GO:0007399//nervous system development;GO:0006351//transcription, DNA-templated" gi|26006149|dbj|BAC41417.1|/0/mKIAA0360 protein [Mus musculus] 67694 2157 0.82 0.84 0.034765418 Up 0.091551017 Ift74 intraflagellar transport 74 K19679|1|0.0|1000|mmu:67694|intraflagellar transport protein 74 GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding;GO:0005488//binding GO:0033627//cell adhesion mediated by integrin;GO:0006366//transcription from RNA polymerase II promoter;GO:0033627//cell adhesion mediated by integrin;GO:0006366//transcription from RNA polymerase II promoter gi|151101194|ref|NP_080595.2|/0/intraflagellar transport protein 74 homolog isoform 1 [Mus musculus] 269702 7760 0.766666667 0.783333333 0.031026896 Up 0.091551017 Mphosph9 M-phase phosphoprotein 9 K16775|1|0.0|1992|mmu:269702|M-phase phosphoprotein 9 GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043232 - - gi|482661637|ref|NP_001264796.1|/0/M-phase phosphoprotein 9 isoform a [Mus musculus] 66222 1931 1.036666667 1.016666667 -0.028105338 Down 0.091551017 Serpinb1a "serine (or cysteine) peptidase inhibitor, clade B, member 1a" K13963|1|0.0|715|mmu:66222|serpin B - - - gi|114158675|ref|NP_079705.2|/0/leukocyte elastase inhibitor A [Mus musculus] 381560 4238 1.026666667 1.05 0.032421478 Up 0.091551017 Xkr8 X-linked Kx blood group related 8 "K01128|1|2e-56|224|clv:102091645|sphingomyelin phosphodiesterase acid-like 3 [EC:3.1.4.-];K03847|2|1e-06|43.9|cge:100770096|alpha-1,6-mannosyltransferase [EC:2.4.1.260]" - - - - 20356 10809 0.68 0.696666667 0.03493379 Up 0.091551017 Sema5a "sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A" K06841|1|0.0|2127|mmu:20356|semaphorin 5 GO:0031224//intrinsic component of membrane GO:0004888//transmembrane signaling receptor activity GO:0048869//cellular developmental process;GO:0001525//angiogenesis;GO:0006935//chemotaxis;GO:0060562//epithelial tube morphogenesis;GO:0007154//cell communication gi|119226253|ref|NP_033180.2|/0/semaphorin-5A precursor [Mus musculus] 667977 1357 0.87 0.886666667 0.027376439 Up 0.091551017 Gm8909 predicted gene 8909 "K06751|1|0.0|701|mmu:667977|major histocompatibility complex, class I" GO:0044459;GO:0009986//cell surface GO:0005515//protein binding GO:0002484;GO:0002664//regulation of T cell tolerance induction;GO:0009581;GO:0001817//regulation of cytokine production gi|326320033|ref|NP_001074501.2|/0/uncharacterized protein LOC667977 precursor [Mus musculus] 53374 6129 0.84 0.82 -0.034765418 Down 0.091551017 Chst3 carbohydrate (chondroitin 6/keratan) sulfotransferase 3 K01020|1|0.0|870|mmu:53374|chondroitin 6-sulfotransferase 3 [EC:2.8.2.17] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0034481//chondroitin sulfotransferase activity GO:0006024//glycosaminoglycan biosynthetic process;GO:0044238//primary metabolic process;GO:0002260//lymphocyte homeostasis;GO:0006928//movement of cell or subcellular component;GO:0044237//cellular metabolic process gi|256985176|ref|NP_058083.2|/0/carbohydrate sulfotransferase 3 [Mus musculus] 68567 1266 0.81 0.826666667 0.029383807 Up 0.091551017 Cgref1 cell growth regulator with EF hand domain 1 K20364|1|2e-07|59.3|tad:TRIADDRAFT_59230|multiple coagulation factor deficiency protein 2 - GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0022402//cell cycle process;GO:0022610;GO:0016049//cell growth;GO:0022402//cell cycle process;GO:0022610;GO:0016049//cell growth gi|236467129|ref|NP_081046.1|/1.40331e-150/cell growth regulator with EF hand domain protein 1 isoform 1 [Mus musculus] 331004 3492 1.07 1.09 0.026717338 Up 0.091551017 Slc9a9 "solute carrier family 9 (sodium/hydrogen exchanger), member 9" "K14725|1|0.0|1120|mmu:331004|solute carrier family 9 (sodium/hydrogen exchanger), member 9" GO:0005770//late endosome;GO:0031224//intrinsic component of membrane GO:0005451//monovalent cation:proton antiporter activity GO:0044763;GO:0055067;GO:0006814//sodium ion transport "gi|148688985|gb|EDL20932.1|/0/solute carrier family 9 (sodium/hydrogen exchanger), isoform 9, isoform CRA_c, partial [Mus musculus]" 58894 6137 1.163333333 1.143333333 -0.02501846 Down 0.091551017 Zfp862-ps "zinc finger protein 862, pseudogene" K09228|1|6e-13|80.5|cmy:102944908|KRAB domain-containing zinc finger protein - - - "gi|859854232|ref|XP_012918639.1|/0/PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 862, partial [Mustela putorius furo]" 75906 3950 0.16 0.173333333 0.115477217 Up 0.091409982 Fam184a "family with sequence similarity 184, member A" K20478|1|9e-33|145|sko:100376626|golgin subfamily B member 1 - - - gi|124487475|ref|NP_001074897.1|/0/protein FAM184A [Mus musculus] 624219 887 0.173333333 0.16 -0.115477217 Down 0.091409982 Angptl8 angiopoietin-like 8 K08767|1|8e-08|60.1|phi:102104848|angiopoietin-like 4 - - - - 269582 5011 0.173333333 0.16 -0.115477217 Down 0.091409982 Clspn claspin - - - - "gi|148698336|gb|EDL30283.1|/0/claspin homolog (Xenopus laevis), isoform CRA_b, partial [Mus musculus]" 243312 3835 0.113333333 0.123333333 0.121990524 Up 0.091409982 Elfn1 "leucine rich repeat and fibronectin type III, extracellular 1" K17567|1|0.0|1347|mmu:243312|protein phosphatase 1 regulatory subunit 28 GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0045202//synapse GO:0019899//enzyme binding GO:0010921//regulation of phosphatase activity;GO:0016043//cellular component organization;GO:0044092//negative regulation of molecular function gi|30425288|ref|NP_780731.1|/0/protein ELFN1 precursor [Mus musculus] 12235 4334.19 0.083333333 0.076666667 -0.120294234 Down 0.091409982 Bub1 "BUB1, mitotic checkpoint serine/threonine kinase" K02178|1|0.0|2102|mmu:12235|checkpoint serine/threonine-protein kinase [EC:2.7.11.1] - - - - 207227 11821 0.076666667 0.083333333 0.120294234 Up 0.091409982 Stxbp5l syntaxin binding protein 5-like K08518|1|0.0|2282|mmu:207227|syntaxin-binding protein 5 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0000149//SNARE binding;GO:0000149//SNARE binding;GO:0000149//SNARE binding;GO:0000149//SNARE binding GO:0050796//regulation of insulin secretion;GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0033500//carbohydrate homeostasis;GO:0050796//regulation of insulin secretion;GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0033500//carbohydrate homeostasis;GO:0050796//regulation of insulin secretion;GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0033500//carbohydrate homeostasis;GO:0050796//regulation of insulin secretion;GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0033500//carbohydrate homeostasis gi|167830462|ref|NP_001108084.1|/0/syntaxin-binding protein 5-like isoform b [Mus musculus] 66985 1530 0.16 0.173333333 0.115477217 Up 0.091409982 Rassf7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 K09855|1|2e-141|504|mmu:66985|Ras association domain-containing protein 7/8 - - - gi|118403310|ref|NP_080162.3|/1.66821e-140/ras association domain-containing protein 7 [Mus musculus] 56846 1810 0.113333333 0.123333333 0.121990524 Up 0.091409982 Necab3 N-terminal EF-hand calcium binding protein 3 - GO:0031985//Golgi cisterna;GO:0031090//organelle membrane GO:0046872//metal ion binding GO:0010559//regulation of glycoprotein biosynthetic process gi|148922939|ref|NP_067521.2|/0/N-terminal EF-hand calcium-binding protein 3 [Mus musculus] 69700 6128 0.166666667 0.153333333 -0.120294234 Down 0.091409982 Col22a1 "collagen, type XXII, alpha 1" "K16630|1|0.0|1119|mmu:69700|collagen, type XXII, alpha" - - - gi|254692857|ref|NP_081450.1|/0/collagen alpha-1(XXII) chain precursor [Mus musculus] 100503969 691 0.083333333 0.076666667 -0.120294234 Down 0.091409982 1810008I18Rik RIKEN cDNA 1810008I18 gene - - - - - 101786 1815 0.113333333 0.123333333 0.121990524 Up 0.091409982 A730082K24Rik RIKEN cDNA A730082K24 gene - - - - gi|148685136|gb|EDL17083.1|/9.94778e-10/mCG147577 [Mus musculus] 381232 5292 0.126666667 0.116666667 -0.118644496 Down 0.091409982 Mirt1 myocardial infarction associated transcript 1 - - - - "gi|148669754|gb|EDL01701.1|/2.80015e-59/mCG140387, isoform CRA_b [Mus musculus]" 207798 3276 0.116666667 0.126666667 0.118644496 Up 0.091409982 Gramd1c GRAM domain containing 1C - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|755553295|ref|XP_006521960.2|/0/PREDICTED: GRAM domain-containing protein 1C isoform X5 [Mus musculus] 51811 2400 0.083333333 0.076666667 -0.120294234 Down 0.091409982 Clec4f "C-type lectin domain family 4, member f" K10060|1|0.0|1056|mmu:51811|C-type lectin domain family 4 member F GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0016192//vesicle-mediated transport gi|31560464|ref|NP_058031.2|/0/C-type lectin domain family 4 member F [Mus musculus] 217593 2166 0.083333333 0.09 0.111031312 Up 0.091005679 Slc25a21 "solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21" "K15110|1|2e-169|598|mmu:217593|solute carrier family 25 (mitochondrial 2-oxodicarboxylate transporter), member 21" GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - GO:0051234//establishment of localization;GO:0051234//establishment of localization gi|269784687|ref|NP_766165.2|/1.66535e-168/mitochondrial 2-oxodicarboxylate carrier isoform 1 [Mus musculus] 270109 7254 0.09 0.083333333 -0.111031312 Down 0.091005679 Pcnx2 pecanex homolog 2 - - - - gi|126352572|ref|NP_780770.2|/0/pecanex-like protein 2 [Mus musculus] 54427 1129 0.133333333 0.123333333 -0.112474729 Down 0.091005679 Dnmt3l DNA (cytosine-5-)-methyltransferase 3-like K17400|1|0.0|787|mmu:54427|DNA (cytosine-5)-methyltransferase 3-like GO:0000790//nuclear chromatin;GO:0044444//cytoplasmic part;GO:0000790//nuclear chromatin;GO:0044444//cytoplasmic part;GO:0000790//nuclear chromatin;GO:0044444//cytoplasmic part;GO:0000790//nuclear chromatin;GO:0044444//cytoplasmic part;GO:0000790//nuclear chromatin;GO:0044444//cytoplasmic part;GO:0000790//nuclear chromatin;GO:0044444//cytoplasmic part GO:0043169//cation binding;GO:0016741;GO:0030234//enzyme regulator activity;GO:0005515//protein binding;GO:0043169//cation binding;GO:0016741;GO:0030234//enzyme regulator activity;GO:0005515//protein binding;GO:0043169//cation binding;GO:0016741;GO:0030234//enzyme regulator activity;GO:0005515//protein binding;GO:0043169//cation binding;GO:0016741;GO:0030234//enzyme regulator activity;GO:0005515//protein binding;GO:0043169//cation binding;GO:0016741;GO:0030234//enzyme regulator activity;GO:0005515//protein binding;GO:0043169//cation binding;GO:0016741;GO:0030234//enzyme regulator activity;GO:0005515//protein binding "GO:0043009//chordate embryonic development;GO:0044093;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0043009//chordate embryonic development;GO:0044093;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0043009//chordate embryonic development;GO:0044093;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0043009//chordate embryonic development;GO:0044093;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0043009//chordate embryonic development;GO:0044093;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0043009//chordate embryonic development;GO:0044093;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated" "gi|148699801|gb|EDL31748.1|/9.0455e-79/DNA (cytosine-5-)-methyltransferase 3-like, isoform CRA_a, partial [Mus musculus]" 15399 1775 0.14 0.13 -0.106915204 Down 0.091005679 Hoxa2 homeobox A2 K09302|1|4e-163|577|mmu:15399|homeobox protein HoxA/B2 GO:0031981//nuclear lumen GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0007411//axon guidance;GO:0001649//osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0045165//cell fate commitment;GO:0003002//regionalization;GO:0042471//ear morphogenesis;GO:0021569//rhombomere 3 development gi|488599464|ref|XP_004484860.1|/1.95376e-167/PREDICTED: homeobox protein Hox-A2 [Dasypus novemcinctus] 245537 3899 0.176666667 0.163333333 -0.11321061 Down 0.091005679 Nlgn3 neuroligin 3 K07378|1|0.0|1602|mmu:245537|neuroligin "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0045202//synapse" GO:0005515//protein binding "GO:0060078//regulation of postsynaptic membrane potential;GO:0051705;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:0007409//axonogenesis;GO:0045838//positive regulation of membrane potential;GO:0016337//single organismal cell-cell adhesion;GO:0007632//visual behavior;GO:0035249//synaptic transmission, glutamatergic;GO:0050807//regulation of synapse organization;GO:0010469//regulation of receptor activity;GO:0006897//endocytosis;GO:0001941//postsynaptic membrane organization;GO:0050804//modulation of synaptic transmission;GO:0048814//regulation of dendrite morphogenesis;GO:0007416//synapse assembly" gi|50510949|dbj|BAD32460.1|/0/mKIAA1480 protein [Mus musculus] 78603 1178 0.09 0.083333333 -0.111031312 Down 0.091005679 B230216N24Rik RIKEN cDNA B230216N24 gene - - - - "gi|148707948|gb|EDL39895.1|/6.74274e-32/mCG146138, partial [Mus musculus]" 69352 4936 0.126666667 0.136666667 0.109624491 Up 0.091005679 Necab1 N-terminal EF-hand calcium binding protein 1 - GO:0031981//nuclear lumen GO:0043169//cation binding - gi|568927338|ref|XP_006538297.1|/8.97845e-161/PREDICTED: N-terminal EF-hand calcium-binding protein 1 isoform X1 [Mus musculus] 233549 1787 0.14 0.13 -0.106915204 Down 0.091005679 Mogat2 monoacylglycerol O-acyltransferase 2 K14457|1|0.0|690|mmu:233549|2-acylglycerol O-acyltransferase 2 [EC:2.3.1.22] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0016411//acylglycerol O-acyltransferase activity GO:0022600//digestive system process;GO:0019400;GO:0006641//triglyceride metabolic process;GO:0046339//diacylglycerol metabolic process gi|28974982|ref|NP_803231.1|/0/2-acylglycerol O-acyltransferase 2 [Mus musculus] 22685 2648 0.093333333 0.086666667 -0.106915204 Down 0.091005679 Zfp239 zinc finger protein 239 K09228|1|1e-88|312|ptg:102948562|KRAB domain-containing zinc finger protein - - - gi|672050947|ref|XP_008761490.1|/2.44916e-138/PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 239 isoform X2 [Rattus norvegicus] 320116 2263 0.13 0.14 0.106915204 Up 0.091005679 Fndc9 fibronectin type III domain containing 9 K06252|1|4e-06|56.2|oaa:100084981|tenascin GO:0031224//intrinsic component of membrane - - "gi|148701878|gb|EDL33825.1|/3.25065e-135/mCG51652, partial [Mus musculus]" 170439 5951 0.086666667 0.093333333 0.106915204 Up 0.091005679 Elovl6 "ELOVL family member 6, elongation of long chain fatty acids (yeast)" K10203|1|4e-156|556|mmu:170439|elongation of very long chain fatty acids protein 6 [EC:2.3.1.199] GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0004312//fatty acid synthase activity;GO:0005488//binding "GO:0035336//long-chain fatty-acyl-CoA metabolic process;GO:0006641//triglyceride metabolic process;GO:0019368//fatty acid elongation, unsaturated fatty acid;GO:0001676//long-chain fatty acid metabolic process" gi|18496985|ref|NP_569717.1|/3.086e-155/elongation of very long chain fatty acids protein 6 [Mus musculus] 11692 1775 10.99 10.95 -0.005260516 Down 0.090789424 Gfer "growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration)" K17783|1|1e-102|376|mmu:11692|mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2];K10382|4|2e-85|319|mmu:13518|dystonin GO:0005740//mitochondrial envelope "GO:0015036//disulfide oxidoreductase activity;GO:0005102//receptor binding;GO:0016670//oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor;GO:0000166//nucleotide binding" GO:0044710 "gi|148690406|gb|EDL22353.1|/7.56332e-103/mCG12842, isoform CRA_a, partial [Mus musculus]" 69710 5086.11 6.373333333 6.33 -0.009842618 Down 0.090789424 Arap1 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1" "K18439|1|0.0|1512|mmu:69710|Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1" GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031982//vesicle GO:0046914//transition metal ion binding;GO:0031701//angiotensin receptor binding;GO:0043168//anion binding;GO:0008289//lipid binding;GO:0046914//transition metal ion binding;GO:0031701//angiotensin receptor binding;GO:0043168//anion binding;GO:0008289//lipid binding;GO:0046914//transition metal ion binding;GO:0031701//angiotensin receptor binding;GO:0043168//anion binding;GO:0008289//lipid binding GO:0022604//regulation of cell morphogenesis;GO:0006928//movement of cell or subcellular component;GO:0031346//positive regulation of cell projection organization;GO:0032232//negative regulation of actin filament bundle assembly;GO:0032012//regulation of ARF protein signal transduction;GO:0022604//regulation of cell morphogenesis;GO:0006928//movement of cell or subcellular component;GO:0031346//positive regulation of cell projection organization;GO:0032232//negative regulation of actin filament bundle assembly;GO:0032012//regulation of ARF protein signal transduction;GO:0022604//regulation of cell morphogenesis;GO:0006928//movement of cell or subcellular component;GO:0031346//positive regulation of cell projection organization;GO:0032232//negative regulation of actin filament bundle assembly;GO:0032012//regulation of ARF protein signal transduction "gi|568951383|ref|XP_006508259.1|/0/PREDICTED: arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X6 [Mus musculus]" 108857 8251 5.576666667 5.613333333 0.009454693 Up 0.090789424 Ankhd1 ankyrin repeat and KH domain containing 1 K16726|1|0.0|4366|mmu:108857|ankyrin repeat domain-containing protein 17 - - - - 98732 7003 4.826666667 4.786666667 -0.012005853 Down 0.090789424 Rab3gap2 RAB3 GTPase activating protein subunit 2 K19937|1|0.0|2672|mmu:98732|Rab3 GTPase-activating protein non-catalytic subunit - - - gi|255003810|ref|NP_001157226.1|/0/rab3 GTPase-activating protein non-catalytic subunit [Mus musculus] 225876 7268 7.526666667 7.566666667 0.007646811 Up 0.090789424 Kdm2a lysine (K)-specific demethylase 2A K10276|1|0.0|2158|mmu:225876|F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27] GO:0031981//nuclear lumen;GO:0000785//chromatin "GO:0016741;GO:0046914//transition metal ion binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0043565//sequence-specific DNA binding" "GO:0070076//histone lysine demethylation;GO:0006351//transcription, DNA-templated" gi|100818178|ref|NP_001001984.2|/0/lysine-specific demethylase 2A [Mus musculus] 13860 4109.06 4.35 4.313333333 -0.012212189 Down 0.090789424 Eps8 epidermal growth factor receptor pathway substrate 8 K17277|1|0.0|1402|mmu:13860|epidermal growth factor receptor kinase substrate 8 GO:0044327//dendritic spine head;GO:0008328//ionotropic glutamate receptor complex;GO:0044327//dendritic spine head;GO:0008328//ionotropic glutamate receptor complex;GO:0044327//dendritic spine head;GO:0008328//ionotropic glutamate receptor complex;GO:0044327//dendritic spine head;GO:0008328//ionotropic glutamate receptor complex;GO:0044327//dendritic spine head;GO:0008328//ionotropic glutamate receptor complex - GO:0007015//actin filament organization;GO:0030534//adult behavior;GO:0007626//locomotory behavior;GO:0007015//actin filament organization;GO:0030534//adult behavior;GO:0007626//locomotory behavior;GO:0007015//actin filament organization;GO:0030534//adult behavior;GO:0007626//locomotory behavior;GO:0007015//actin filament organization;GO:0030534//adult behavior;GO:0007626//locomotory behavior;GO:0007015//actin filament organization;GO:0030534//adult behavior;GO:0007626//locomotory behavior gi|409264628|ref|NP_001258516.1|/0/epidermal growth factor receptor kinase substrate 8 isoform 2 [Mus musculus] 14674 6217 4.646666667 4.603333333 -0.013517242 Down 0.090789424 Gna13 "guanine nucleotide binding protein, alpha 13" K04639|1|0.0|756|mmu:14674|guanine nucleotide-binding protein subunit alpha-13 - - - "gi|148702406|gb|EDL34353.1|/0/guanine nucleotide binding protein, alpha 13, isoform CRA_a, partial [Mus musculus]" 408067 3792 4.536666667 4.5 -0.01170766 Down 0.090789424 Zfp874b zinc finger protein 874b K09228|1|0.0|962|mmu:408067|KRAB domain-containing zinc finger protein - - - gi|115647917|ref|NP_001070259.1|/0/zinc finger protein 874b [Mus musculus] 320487 7761 4.236666667 4.196666667 -0.013685747 Down 0.090789424 Heatr5a HEAT repeat containing 5A - - - - "gi|148704826|gb|EDL36773.1|/0/RIKEN cDNA D930036F22, isoform CRA_a, partial [Mus musculus]" 192976 2047 4.05 4.013333333 -0.013120922 Down 0.090789424 Lrrc75a leucine rich repeat containing 75A - - - - gi|38524604|ref|NP_942561.1|/5.97533e-163/leucine-rich repeat-containing protein 75A [Mus musculus] 26428 3750.26 5.063333333 5.023333333 -0.011442453 Down 0.090789424 Orc4 "origin recognition complex, subunit 4" K02606|1|3e-65|251|mmu:26428|origin recognition complex subunit 4 GO:0043231//intracellular membrane-bounded organelle;GO:0000808//origin recognition complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000808//origin recognition complex;GO:0043231//intracellular membrane-bounded organelle;GO:0000808//origin recognition complex GO:0032550;GO:0043565//sequence-specific DNA binding;GO:0016462//pyrophosphatase activity;GO:0032550;GO:0043565//sequence-specific DNA binding;GO:0016462//pyrophosphatase activity;GO:0032550;GO:0043565//sequence-specific DNA binding;GO:0016462//pyrophosphatase activity GO:0006259//DNA metabolic process;GO:0006259//DNA metabolic process;GO:0006259//DNA metabolic process gi|124286818|ref|NP_036088.3|/0/origin recognition complex subunit 4 isoform 1 [Mus musculus] 74895 1938 4.966666667 4.923333333 -0.012642505 Down 0.090789424 Ccdc181 coiled-coil domain containing 181 - GO:0031981//nuclear lumen - - gi|229577050|ref|NP_083391.2|/0/coiled-coil domain-containing protein 181 [Mus musculus] 381218 2152 7.453333333 7.49 0.007079936 Up 0.090789424 4430402I18Rik RIKEN cDNA 4430402I18 gene K12172|1|3e-33|146|cin:100180766|E3 SUMO-protein ligase RanBP2;K13172|2|2e-07|60.8|lgi:LOTGIDRAFT_157663|serine/arginine repetitive matrix protein 2 - - - gi|569007433|ref|XP_006527221.1|/0/PREDICTED: spermatogenesis associated 6-like protein isoform X5 [Mus musculus] 264064 2586 5.013333333 4.97 -0.012524309 Down 0.090789424 Cdk8 cyclin-dependent kinase 8 K02208|1|0.0|888|mmu:264064|cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23] GO:0031981//nuclear lumen;GO:0043234//protein complex GO:0032550;GO:0004674//protein serine/threonine kinase activity GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process gi|31652272|ref|NP_705827.2|/0/cyclin-dependent kinase 8 [Mus musculus] 56089 1221 6.993333333 7.036666667 0.008911901 Up 0.090789424 Ramp3 receptor (calcitonin) activity modifying protein 3 K08449|1|7e-69|263|mmu:56089|receptor activity modifying protein 3 GO:0016021//integral component of membrane;GO:0000323//lytic vacuole;GO:0043234//protein complex GO:0038023//signaling receptor activity;GO:0046983//protein dimerization activity;GO:0022892//substrate-specific transporter activity "GO:0006351//transcription, DNA-templated;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001881//receptor recycling;GO:0006898//receptor-mediated endocytosis;GO:0007009//plasma membrane organization;GO:0015031//protein transport;GO:0070838//divalent metal ion transport" gi|9507031|ref|NP_062384.1|/6.16844e-68/receptor activity-modifying protein 3 precursor [Mus musculus] 77578 6102 9.496666667 9.536666667 0.006063876 Up 0.090789424 Bcl9 B cell CLL/lymphoma 9 "K11647|1|5e-10|70.9|cfo:105251812|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-];K19720|2|7e-09|48.1|aml:100472350|collagen, type III, alpha" GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding GO:0016055//Wnt signaling pathway;GO:0019827//stem cell population maintenance;GO:0014902//myotube differentiation;GO:0006366//transcription from RNA polymerase II promoter gi|537265448|gb|ERE90869.1|/0/B-cell CLL/lymphoma 9 protein [Cricetulus griseus] 269003 4015 11.28 11.23666667 -0.005552941 Down 0.090789424 Sap130 Sin3A associated protein K19192|1|0.0|1692|mmu:269003|histone deacetylase complex subunit SAP130 - - - "gi|148664619|gb|EDK97035.1|/0/Sin3A associated protein, 130kDa, isoform CRA_c, partial [Mus musculus]" 219132 2696 4.663333333 4.7 0.0112992 Up 0.090789424 Phf11d PHD finger protein 11D K18494|1|9e-130|467|mmu:107303348|histone-lysine N-methyltransferase SETDB2 [EC:2.1.1.43];K14959|5|3e-12|77.0|amj:102571979|histone-lysine N-methyltransferase MLL4 [EC:2.1.1.43] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|259530879|sp|A6H5X4.1|PHF11_MOUSE/0/RecName: Full=PHD finger protein 11; AltName: Full=PHD finger protein 11-like; AltName: Full=PHD finger protein 11D 21826 5922 5.133333333 5.09 -0.012230289 Down 0.090789424 Thbs2 thrombospondin 2 K04659|1|0.0|2293|mmu:21826|thrombospondin 2/3/4/5 GO:0005578//proteinaceous extracellular matrix GO:0005539//glycosaminoglycan binding GO:0001525//angiogenesis;GO:0022610;GO:0007416//synapse assembly gi|239787900|ref|NP_035711.2|/0/thrombospondin-2 precursor [Mus musculus] 14628 3009 9.566666667 9.53 -0.005540117 Down 0.090789424 Ostm1 osteopetrosis associated transmembrane protein 1 - GO:0005764//lysosome;GO:0016020//membrane - GO:0002573//myeloid leukocyte differentiation gi|27369545|ref|NP_766004.1|/4.272e-139/osteopetrosis-associated transmembrane protein 1 precursor [Mus musculus] 20534 2445 6.736666667 6.776666667 0.008540893 Up 0.090789424 Slc4a1ap "solute carrier family 4 (anion exchanger), member 1, adaptor protein" K10147|1|6e-93|344|soc:105198940|protein phosphatase 1D [EC:3.1.3.16];K06091|2|2e-75|286|tsp:Tsp_03061|MAGUK p55 subfamily member 5;K13216|3|8e-13|78.6|obi:106875745|nuclear inhibitor of protein phosphatase 1 [EC:3.1.4.-] - - - gi|155722992|ref|NP_033232.2|/0/kanadaptin [Mus musculus] 230908 7299.31 7.096666667 7.14 0.00878253 Up 0.090789424 Tardbp TAR DNA binding protein K03993|1|3e-139|499|mmu:17175|mannan-binding lectin serine protease 2 [EC:3.4.21.104] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003729//mRNA binding;GO:0043566//structure-specific DNA binding;GO:0003729//mRNA binding;GO:0043566//structure-specific DNA binding;GO:0003729//mRNA binding;GO:0043566//structure-specific DNA binding;GO:0003729//mRNA binding;GO:0043566//structure-specific DNA binding;GO:0003729//mRNA binding;GO:0043566//structure-specific DNA binding "GO:0006396//RNA processing;GO:0032897//negative regulation of viral transcription;GO:0048255//mRNA stabilization;GO:0006351//transcription, DNA-templated;GO:0006396//RNA processing;GO:0032897//negative regulation of viral transcription;GO:0048255//mRNA stabilization;GO:0006351//transcription, DNA-templated;GO:0006396//RNA processing;GO:0032897//negative regulation of viral transcription;GO:0048255//mRNA stabilization;GO:0006351//transcription, DNA-templated;GO:0006396//RNA processing;GO:0032897//negative regulation of viral transcription;GO:0048255//mRNA stabilization;GO:0006351//transcription, DNA-templated;GO:0006396//RNA processing;GO:0032897//negative regulation of viral transcription;GO:0048255//mRNA stabilization;GO:0006351//transcription, DNA-templated" gi|56682931|ref|NP_001003899.1|/1.19967e-168/TAR DNA-binding protein 43 isoform 3 [Mus musculus] 28018 4831 5.65 5.606666667 -0.011107568 Down 0.090789424 Ubfd1 ubiquitin family domain containing 1 - - - - gi|77917602|ref|NP_613055.2|/8.73269e-177/ubiquitin domain-containing protein UBFD1 [Mus musculus] 15902 1289 6.906666667 6.943333333 0.007638836 Up 0.090789424 Id2 inhibitor of DNA binding 2 K17693|1|5e-71|270|rro:104675219|DNA-binding protein inhibitor ID2 GO:0031981//nuclear lumen;GO:0032991//macromolecular complex;GO:0044444//cytoplasmic part;GO:0044427 GO:0046983//protein dimerization activity GO:0060644//mammary gland epithelial cell differentiation;GO:0021700//developmental maturation;GO:0003164;GO:0008284//positive regulation of cell proliferation;GO:0021988//olfactory lobe development;GO:0050673//epithelial cell proliferation;GO:0045687//positive regulation of glial cell differentiation;GO:0021782//glial cell development;GO:0048546//digestive tract morphogenesis;GO:0051100//negative regulation of binding;GO:0008217//regulation of blood pressure;GO:0001822//kidney development;GO:0006629//lipid metabolic process;GO:0007569//cell aging;GO:0045686//negative regulation of glial cell differentiation;GO:1901990//regulation of mitotic cell cycle phase transition;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0045444//fat cell differentiation;GO:0001649//osteoblast differentiation;GO:0009605//response to external stimulus;GO:0010226//response to lithium ion;GO:0030182//neuron differentiation;GO:0007050//cell cycle arrest;GO:0030183//B cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0030218//erythrocyte differentiation;GO:0048537//mucosal-associated lymphoid tissue development gi|109791|pir||A41689/2.16918e-76/DNA-binding protein inhibitor Id-2 - mouse 226252 5630 4.126666667 4.09 -0.012876066 Down 0.090789424 Fam160b1 "family with sequence similarity 160, member B1" - - - - "gi|148669833|gb|EDL01780.1|/0/expressed sequence AI450540, isoform CRA_a [Mus musculus]" 67326 1267.47 8.353333333 8.313333333 -0.006924949 Down 0.090789424 1700037H04Rik RIKEN cDNA 1700037H04 gene - - - - - 15473 1011 3.626666667 3.59 -0.014660307 Down 0.090789424 Rida reactive intermediate imine deaminase A homolog K06927|1|6e-10|67.4|tru:101077017|diphthine-ammonia ligase [EC:6.3.1.14] GO:0042579//microbody;GO:0031981//nuclear lumen GO:0004518//nuclease activity - "gi|148676899|gb|EDL08846.1|/7.33508e-82/heat-responsive protein 12, partial [Mus musculus]" 80898 4014 7.063333333 7.1 0.007469843 Up 0.090789424 Erap1 endoplasmic reticulum aminopeptidase 1 K09604|1|0.0|1769|mmu:80898|adipocyte-derived leucine aminopeptidase [EC:3.4.11.-] GO:0031224//intrinsic component of membrane;GO:0044432;GO:0031090//organelle membrane GO:0046914//transition metal ion binding;GO:0008238//exopeptidase activity;GO:0008237//metallopeptidase activity;GO:0032813//tumor necrosis factor receptor superfamily binding GO:0051707//response to other organism;GO:0001525//angiogenesis;GO:0002376//immune system process;GO:0033619//membrane protein proteolysis gi|13507656|ref|NP_109636.1|/0/endoplasmic reticulum aminopeptidase 1 precursor [Mus musculus] 50817 3288 3.91 3.946666667 0.013466068 Up 0.090789424 Capn15 calpain 15 K08582|1|0.0|1956|mmu:50817|calpain-15 [EC:3.4.22.-] GO:0044464 "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process gi|7657601|ref|NP_056645.1|/0/calpain-15 [Mus musculus] 107477 1681 0.1 0.093333333 -0.099535674 Down 0.090638986 Guca1b guanylate cyclase activator 1B K08328|1|2e-113|412|mmu:107477|guanylate cyclase activator 1 GO:0044464;GO:0016020//membrane GO:0030250//guanylate cyclase activator activity;GO:0046872//metal ion binding GO:0031281//positive regulation of cyclase activity;GO:0050953//sensory perception of light stimulus;GO:0007165//signal transduction;GO:0030826//regulation of cGMP biosynthetic process gi|22122571|ref|NP_666191.1|/1.67896e-112/guanylyl cyclase-activating protein 2 [Mus musculus] 70113 1075 0.19 0.176666667 -0.10496956 Down 0.090638986 Odf3b outer dense fiber of sperm tails 3B - - - - gi|61316404|ref|NP_001013040.1|/1.14593e-136/outer dense fiber protein 3B [Mus musculus] 72518 2416 0.096666667 0.103333333 0.096215315 Up 0.090638986 2610307P16Rik RIKEN cDNA 2610307P16 gene - - - - - 11489 7675 0.15 0.14 -0.099535674 Down 0.090638986 Adam12 a disintegrin and metallopeptidase domain 12 (meltrin alpha) K06835|1|0.0|1772|mmu:11489|disintegrin and metalloproteinase domain-containing protein 12 [EC:3.4.24.-] GO:0031224//intrinsic component of membrane "GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0022610 gi|117606341|ref|NP_031426.2|/0/disintegrin and metalloproteinase domain-containing protein 12 precursor [Mus musculus] 235402 3321 0.146666667 0.156666667 0.095157233 Up 0.090638986 Lingo1 leucine rich repeat and Ig domain containing 1 K15235|1|3e-40|170|fpg:101911799|josephin [EC:3.4.19.12];K16360|2|3e-40|170|phi:102108664|netrin-G3 ligand - GO:0070851//growth factor receptor binding GO:0045686//negative regulation of glial cell differentiation;GO:0021953//central nervous system neuron differentiation;GO:0030030//cell projection organization gi|568961311|ref|XP_006511149.1|/0/PREDICTED: leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform X2 [Mus musculus] 73696 951 0.15 0.14 -0.099535674 Down 0.090638986 Platr9 pluripotency associated transcript 9 - - - - "gi|148673513|gb|EDL05460.1|/4.2019e-28/mCG1043129, partial [Mus musculus]" 100503498 1319 0.19 0.203333333 0.097847323 Up 0.090638986 Gm16675 "predicted gene, 16675" - - - - - 72958 3274 0.143333333 0.133333333 -0.10433666 Down 0.090638986 Zfp493 zinc finger protein 493 K09228|1|0.0|809|mmu:212569|KRAB domain-containing zinc finger protein - - - gi|38049077|tpg|DAA01863.1|/0/TPA_exp: regulator of sex-limitation candidate 12 [Mus musculus] 67580 1249 0.1 0.093333333 -0.099535674 Down 0.090638986 Lrrc18 leucine rich repeat containing 18 K10130|1|3e-21|105|lcm:102348313|leucine-rich repeats and death domain-containing protein GO:0044424;GO:0044424 - - "gi|148692902|gb|EDL24849.1|/2.07049e-151/leucine rich repeat containing 18, partial [Mus musculus]" 12659 2525 0.156666667 0.146666667 -0.095157233 Down 0.090638986 Ovgp1 oviductal glycoprotein 1 K17526|1|0.0|998|mmu:12659|oviduct-specific glycoprotein "GO:0016023//cytoplasmic, membrane-bounded vesicle" "GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds" GO:0009566//fertilization;GO:0044238//primary metabolic process;GO:0006026 gi|33468849|ref|NP_031722.1|/0/oviduct-specific glycoprotein precursor [Mus musculus] 100036537 1275 0.156666667 0.146666667 -0.095157233 Down 0.090638986 Gm11149 predicted gene 11149 K06491|1|1e-22|110|hgl:101707044|neural cell adhesion molecule - - - - 22420 2068 0.186666667 0.2 0.099535674 Up 0.090638986 Wnt6 "wingless-type MMTV integration site family, member 6" "K00445|1|1e-180|635|mmu:22420|wingless-type MMTV integration site family, member 6" GO:0044464;GO:0031012//extracellular matrix GO:0005515//protein binding "GO:0006351//transcription, DNA-templated;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0034505//tooth mineralization;GO:0007389//pattern specification process;GO:0048754//branching morphogenesis of an epithelial tube;GO:0061326//renal tubule development;GO:0001838//embryonic epithelial tube formation" gi|34328158|ref|NP_033552.2|/1.21191e-179/protein Wnt-6 precursor [Mus musculus] 100039801 663 0.09 0.096666667 0.103093493 Up 0.090638986 Cldn24 claudin 24 K06087|1|1e-70|267|mmu:100039801|claudin - - - gi|148703667|gb|EDL35614.1|/1.08401e-69/mCG51871 [Mus musculus] 269224 5119 0.093333333 0.1 0.099535674 Up 0.090638986 Pask PAS domain containing serine/threonine kinase K08801|1|0.0|2635|mmu:269224|PAS domain containing serine/threonine kinase [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0060089;GO:0004672//protein kinase activity;GO:0005543//phospholipid binding GO:0007585//respiratory gaseous exchange;GO:0032844//regulation of homeostatic process;GO:0006468//protein phosphorylation;GO:0005978//glycogen biosynthetic process;GO:0070091//glucagon secretion gi|37359790|dbj|BAC97873.1|/0/mKIAA0135 protein [Mus musculus] 216049 4279 0.196666667 0.183333333 -0.101283336 Down 0.090638986 Zfp365 zinc finger protein 365 K16737|1|0.0|774|mmu:216049|protein ZNF365 - - - - 20349 6877 0.09 0.096666667 0.103093493 Up 0.090638986 Sema3e "sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E" K06840|1|0.0|1545|mmu:20349|semaphorin 3 GO:0044421 - GO:0001525//angiogenesis;GO:0022604//regulation of cell morphogenesis;GO:0031532//actin cytoskeleton reorganization;GO:0006935//chemotaxis;GO:0007166//cell surface receptor signaling pathway;GO:0001952//regulation of cell-matrix adhesion gi|113199777|ref|NP_035478.2|/0/semaphorin-3E precursor [Mus musculus] 14715 2265 0.146666667 0.156666667 0.095157233 Up 0.090638986 Gnrhr gonadotropin releasing hormone receptor K04280|1|2e-108|264|pon:100437372|gonadotropin-releasing hormone receptor GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0016500//protein-hormone receptor activity;GO:0005488//binding;GO:0016500//protein-hormone receptor activity;GO:0005488//binding;GO:0016500//protein-hormone receptor activity GO:0071375//cellular response to peptide hormone stimulus;GO:0008283//cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0071375//cellular response to peptide hormone stimulus;GO:0008283//cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0071375//cellular response to peptide hormone stimulus;GO:0008283//cell proliferation;GO:0007166//cell surface receptor signaling pathway gi|893571074|ref|NP_001297582.1|/3.97985e-134/gonadotropin-releasing hormone receptor isoform 3 [Mus musculus] 19888 3047 0.096666667 0.103333333 0.096215315 Up 0.090638986 Rp1 retinitis pigmentosa 1 (human) K19538|1|7e-139|497|mmu:19888|retinitis pigmentosa 1 GO:0015630//microtubule cytoskeleton;GO:0031513//nonmotile primary cilium;GO:0005930//axoneme GO:0015631//tubulin binding GO:0043010//camera-type eye development;GO:0001578//microtubule bundle formation;GO:0009416//response to light stimulus;GO:0042462//eye photoreceptor cell development;GO:0007601//visual perception;GO:0007165//signal transduction gi|307548909|ref|NP_001182591.1|/8.39271e-151/oxygen-regulated protein 1 isoform 2 [Mus musculus] 74559 5453 0.133333333 0.143333333 0.10433666 Up 0.090638986 Elovl7 "ELOVL family member 7, elongation of long chain fatty acids (yeast)" K10250|1|1e-169|600|mmu:74559|elongation of very long chain fatty acids protein 7 [EC:2.3.1.199] GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane GO:0003824//catalytic activity "GO:0019368//fatty acid elongation, unsaturated fatty acid;GO:0000038//very long-chain fatty acid metabolic process" gi|148540000|ref|NP_083277.3|/1.3015e-168/elongation of very long chain fatty acids protein 7 [Mus musculus] 215493 3390 0.133333333 0.143333333 0.10433666 Up 0.090638986 A3galt2 "alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase)" K00743|1|2e-77|293|pbi:103058654|N-acetyllactosaminide 3-alpha-galactosyltransferase [EC:2.4.1.87] GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0035250//UDP-galactosyltransferase activity GO:0006687//glycosphingolipid metabolic process;GO:0006464//cellular protein modification process "gi|57528488|ref|NP_001009819.1|/0/alpha-1,3-galactosyltransferase 2 [Mus musculus]" 78303 462 0.226666667 0.213333333 -0.087462841 Down 0.090328707 Hist3h2ba "histone cluster 3, H2ba" K11252|1|5e-56|218|ngi:103729051|histone H2B - - - - 434223 8675.05 0.16 0.17 0.087462841 Up 0.090328707 Gm1966 predicted gene 1966 K06551|1|6e-75|286|xtr:101733039|signal-regulatory protein alpha/beta1/gamma;K12797|2|6e-20|104|myb:102249258|caspase recruitment domain-containing protein 6 - - - gi|467087326|ref|NP_001264108.1|/0/predicted gene 1966 [Mus musculus] 80515 1779 0.163333333 0.153333333 -0.091147888 Down 0.090328707 Chd3os "chromodomain helicase DNA binding protein 3, opposite strand" - - - - - 20706 1930 0.106666667 0.1 -0.093109404 Down 0.090328707 Serpinb9b "serine (or cysteine) peptidase inhibitor, clade B, member 9b" K13963|1|0.0|729|mmu:20706|serpin B - - - "gi|15826842|ref|NP_035582.1|/0/serine (or cysteine) proteinase inhibitor, clade B, member 9b [Mus musculus]" 223473 3825 0.113333333 0.106666667 -0.087462841 Down 0.090328707 Nipal2 NIPA-like domain containing 2 K19364|1|5e-18|96.7|cmk:103177121|magnesium transporter NIPA1 GO:0031224//intrinsic component of membrane GO:0046873//metal ion transmembrane transporter activity GO:0070838//divalent metal ion transport gi|47059032|ref|NP_663444.2|/0/NIPA-like protein 2 [Mus musculus] 193286 883 0.173333333 0.163333333 -0.085729874 Down 0.090328707 BC049762 cDNA sequence BC049762 - - - - "gi|148701725|gb|EDL33672.1|/1.19491e-103/cDNA sequence BC049762, isoform CRA_a, partial [Mus musculus]" 109202 1907 0.156666667 0.166666667 0.089267338 Up 0.090328707 A930024E05Rik RIKEN cDNA A930024E05 gene - - - - - 65086 2494 0.16 0.15 -0.093109404 Down 0.090328707 Lpar3 lysophosphatidic acid receptor 3 K04294|1|0.0|674|mmu:65086|lysophosphatidic acid receptor 3 GO:0043227//membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0005515//protein binding;GO:0008289//lipid binding;GO:0045125//bioactive lipid receptor activity GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0006816//calcium ion transport;GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade;GO:0030031//cell projection assembly gi|12667796|ref|NP_075359.1|/0/lysophosphatidic acid receptor 3 [Mus musculus] 56533 8121 0.106666667 0.1 -0.093109404 Down 0.090328707 Rgs17 regulator of G-protein signaling 17 K16449|1|2e-100|371|cge:100770397|regulator of G-protein signaling - - - gi|240120077|ref|NP_001155294.1|/3.80445e-103/regulator of G-protein signaling 17 isoform 1 [Mus musculus] 212539 1231 0.17 0.16 -0.087462841 Down 0.090328707 Gm266 predicted gene 266 K07839|1|1e-46|189|shr:100922336|Ras-related protein Rap-2C;K07837|3|4e-46|187|cmk:103177969|Ras-related protein Rap-2A - - - - 14411 2563 0.113333333 0.106666667 -0.087462841 Down 0.090328707 Slc6a12 "solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12" "K05039|1|0.0|1234|mmu:14411|solute carrier family 6 (neurotransmitter transporter, GABA) member 6/8/11/12/13" GO:0016021//integral component of membrane GO:0005283//sodium:amino acid symporter activity GO:0044765//single-organism transport;GO:0006972//hyperosmotic response;GO:0042221//response to chemical;GO:0006884//cell volume homeostasis gi|92110009|ref|NP_598422.2|/0/sodium- and chloride-dependent betaine transporter [Mus musculus] 226075 7524 0.11 0.103333333 -0.090197809 Down 0.090328707 Glis3 GLIS family zinc finger 3 K09232|1|0.0|1471|ngi:103740987|zinc finger protein GLIS1/3 GO:0005634//nucleus;GO:0005634//nucleus GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter gi|56749063|sp|Q6XP49.2|GLIS3_MOUSE/0/RecName: Full=Zinc finger protein GLIS3; AltName: Full=GLI-similar 3 236285 3920 0.163333333 0.153333333 -0.091147888 Down 0.090328707 Lancl3 LanC lantibiotic synthetase component C-like 3 (bacterial) K19522|1|0.0|697|chx:102176212|membrane transport protein XK - - - gi|803327634|ref|XP_012021978.1|/0/PREDICTED: lanC-like protein 3 isoform X2 [Ovis aries musimon] 57746 4913 0.166666667 0.156666667 -0.089267338 Down 0.090328707 Piwil2 piwi-like RNA-mediated gene silencing 2 K02156|1|0.0|1855|mmu:57746|aubergine GO:0043186//P granule GO:0003723//RNA binding GO:0007127//meiosis I;GO:0016458//gene silencing;GO:0006412//translation;GO:0019827//stem cell population maintenance;GO:0006306//DNA methylation;GO:0034660//ncRNA metabolic process;GO:0007292//female gamete generation;GO:0048232//male gamete generation gi|568988326|ref|XP_006519391.1|/0/PREDICTED: piwi-like protein 2 isoform X2 [Mus musculus] 100044236 2001 0.123333333 0.116666667 -0.080170349 Down 0.089764564 Copg2os2 "coatomer protein complex, subunit gamma 2, opposite strand 2" - - - - - 16425 3139 0.11 0.116666667 0.084888898 Up 0.089764564 Itih2 "inter-alpha trypsin inhibitor, heavy chain 2" K19015|1|0.0|1860|mmu:16425|inter-alpha-trypsin inhibitor heavy chain H2 - GO:0004866//endopeptidase inhibitor activity GO:0030203//glycosaminoglycan metabolic process;GO:0051346//negative regulation of hydrolase activity gi|226874935|ref|NP_034712.2|/0/inter-alpha-trypsin inhibitor heavy chain H2 precursor [Mus musculus] 53623 5213 0.116666667 0.11 -0.084888898 Down 0.089764564 Gria3 "glutamate receptor, ionotropic, AMPA3 (alpha 3)" K05199|1|0.0|1673|ngi:103734852|glutamate receptor 3 GO:0030139//endocytic vesicle;GO:0097060//synaptic membrane;GO:0008328//ionotropic glutamate receptor complex;GO:0031224//intrinsic component of membrane;GO:0097060//synaptic membrane;GO:0031224//intrinsic component of membrane;GO:0097060//synaptic membrane GO:0004970//ionotropic glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0007267//cell-cell signaling;GO:0007166//cell surface receptor signaling pathway;GO:0051234//establishment of localization;GO:0044765//single-organism transport;GO:0007215//glutamate receptor signaling pathway;GO:0044765//single-organism transport;GO:0007215//glutamate receptor signaling pathway gi|60360568|dbj|BAD90527.1|/0/mKIAA4184 protein [Mus musculus] 245945 4705 0.113333333 0.12 0.08246216 Up 0.089764564 Rbm47 RNA binding motif protein 47 K13161|1|2e-88|330|amj:102557895|heterogeneous nuclear ribonucleoprotein R - - - - 54139 4140 0.176666667 0.186666667 0.079434467 Up 0.089764564 Irf6 interferon regulatory factor 6 K10154|1|0.0|932|mmu:54139|interferon regulatory factor 6 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0001071//nucleic acid binding transcription factor activity;GO:0001067 "GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0009913//epidermal cell differentiation;GO:0019221//cytokine-mediated signaling pathway;GO:0022402//cell cycle process;GO:0030855//epithelial cell differentiation" gi|114145467|ref|NP_058547.2|/0/interferon regulatory factor 6 [Mus musculus] 16499 2537 0.173333333 0.183333333 0.080919995 Up 0.089764564 Kcnab3 "potassium voltage-gated channel, shaker-related subfamily, beta member 3" "K04884|1|0.0|691|mmu:16499|potassium voltage-gated channel Shaker-related subfamily A, beta member 3" GO:0031224//intrinsic component of membrane;GO:0044424 GO:0005267//potassium channel activity GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|226823214|ref|NP_034729.3|/0/voltage-gated potassium channel subunit beta-3 [Mus musculus] 619331 2336 0.186666667 0.176666667 -0.079434467 Down 0.089764564 Zfp551 zinc fingr protein 551 K09228|1|0.0|1480|mmu:619331|KRAB domain-containing zinc finger protein - - - gi|162287258|ref|NP_001028992.2|/0/zinc finger protein 551 [Mus musculus] 211936 3944 0.236666667 0.223333333 -0.083657929 Down 0.089764564 Ccdc73 coiled-coil domain containing 73 K17785|1|4e-12|77.0|hmg:100206620|mitofilin;K20478|3|2e-10|71.6|xtr:100495258|golgin subfamily B member 1;K12478|4|3e-10|70.9|pss:102454242|early endosome antigen 1;K20283|5|3e-10|70.9|gfr:102031748|golgin subfamily A member 4 - - - gi|167900444|ref|NP_808268.2|/0/coiled-coil domain-containing protein 73 [Mus musculus] 20472 2108 0.123333333 0.116666667 -0.080170349 Down 0.089764564 Six2 sine oculis-related homeobox 2 K19472|1|6e-126|454|rno:366542|homeobox protein SIX2 GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0009888//tissue development;GO:0006366//transcription from RNA polymerase II promoter;GO:0001708//cell fate specification;GO:0006886//intracellular protein transport;GO:0042471//ear morphogenesis;GO:0048704//embryonic skeletal system morphogenesis gi|586455308|ref|XP_006839478.1|/5.1307e-125/PREDICTED: homeobox protein SIX2 [Chrysochloris asiatica] 224813 1384 0.253333333 0.24 -0.078002512 Down 0.089764564 Lrrc73 leucine rich repeat containing 73 "K12800|1|1e-07|60.1|cmk:103172555|NACHT, LRR and PYD domains-containing protein 3;K16634|2|2e-07|59.7|cge:100773448|ribonuclease inhibitor;K08060|3|3e-06|55.8|cmk:103186082|class II, major histocompatibility complex, transactivator;K17576|4|8e-06|54.3|cin:100186281|protein phosphatase 1 regulatory subunit 37" - - - gi|674042805|ref|XP_008827289.1|/8.22696e-152/PREDICTED: leucine-rich repeat-containing protein 73 [Nannospalax galili] 93707 5047 0.123333333 0.116666667 -0.080170349 Down 0.089764564 Pcdhgc4 "protocadherin gamma subfamily C, 4" K16497|1|0.0|1788|mmu:93707|protocadherin gamma subfamily C - - - gi|18087749|ref|NP_291060.1|/0/protocadherin gamma-C4 [Mus musculus] 102634753 1068 0.236666667 0.223333333 -0.083657929 Down 0.089764564 Gm12440 predicted gene 12440 - - - - - 319930 3361 0.233333333 0.22 -0.084888898 Down 0.089764564 Ceacam19 carcinoembryonic antigen-related cell adhesion molecule 19 K16825|1|4e-121|438|mmu:319930|carcinoembryonic antigen-related cell adhesion molecule 19 - - - gi|28892919|ref|NP_796010.1|/3.85808e-120/carcinoembryonic antigen-related cell adhesion molecule 19 precursor [Mus musculus] 19197 474 0.123333333 0.116666667 -0.080170349 Down 0.089764564 Pspn persephin K05452|1|8e-10|64.7|amj:102566602|glial cell derived neurotrophic factor GO:0044421 GO:0005102//receptor binding GO:0048754//branching morphogenesis of an epithelial tube gi|247269886|ref|NP_032980.2|/3.79384e-66/persephin precursor [Mus musculus] 78906 2427 0.123333333 0.116666667 -0.080170349 Down 0.089764564 Misp mitotic spindle positioning K16519|1|3e-14|83.2|gga:420097|A-kinase anchor protein 2 - - - gi|21313526|ref|NP_084494.1|/0/mitotic interactor and substrate of PLK1 [Mus musculus] 12816 11719 0.116666667 0.11 -0.084888898 Down 0.089764564 Col12a1 "collagen, type XII, alpha 1" "K08132|1|0.0|5478|mmu:12816|collagen, type XII, alpha" - - - gi|594140550|ref|NP_001277237.1|/0/collagen alpha-1(XII) chain precursor [Mus musculus] 75823 1858 0.113333333 0.12 0.08246216 Up 0.089764564 Fam227b "family with sequence similarity 227, member B" - - - - gi|568918758|ref|XP_006500411.1|/0/PREDICTED: protein FAM227B isoform X1 [Mus musculus] 13175 5764.75 0.19 0.18 -0.078002512 Down 0.089764564 Dclk1 doublecortin-like kinase 1 K08805|1|0.0|778|mmu:13175|doublecortin-like kinase 1/2 [EC:2.7.11.1] GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0032550;GO:0004672//protein kinase activity;GO:0004871//signal transducer activity;GO:0032550;GO:0004672//protein kinase activity;GO:0004871//signal transducer activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity;GO:0032550;GO:0004672//protein kinase activity GO:0016477//cell migration;GO:0051707//response to other organism;GO:0016358//dendrite development;GO:0007420//brain development;GO:0006464//cellular protein modification process;GO:0044765//single-organism transport;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction;GO:0021955//central nervous system neuron axonogenesis;GO:0016477//cell migration;GO:0051707//response to other organism;GO:0016358//dendrite development;GO:0007420//brain development;GO:0006464//cellular protein modification process;GO:0044765//single-organism transport;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction;GO:0021955//central nervous system neuron axonogenesis;GO:0016477//cell migration;GO:0051707//response to other organism;GO:0016358//dendrite development;GO:0007420//brain development;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction;GO:0021955//central nervous system neuron axonogenesis;GO:0016477//cell migration;GO:0051707//response to other organism;GO:0016358//dendrite development;GO:0007420//brain development;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction;GO:0021955//central nervous system neuron axonogenesis;GO:0016477//cell migration;GO:0051707//response to other organism;GO:0016358//dendrite development;GO:0007420//brain development;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction;GO:0021955//central nervous system neuron axonogenesis gi|26006151|dbj|BAC41418.1|/0/mKIAA0369 protein [Mus musculus] 77836 461 0.126666667 0.12 -0.078002512 Down 0.089764564 Mlana melan-A K17303|1|6e-46|184|mmu:77836|melanoma antigen recognized by T-cells 1 GO:0031090//organelle membrane;GO:0048770;GO:0016021//integral component of membrane GO:0005488//binding - gi|110625785|ref|NP_084269.1|/4.72337e-45/melanoma antigen recognized by T-cells 1 [Mus musculus] 654472 1742 0.223333333 0.236666667 0.083657929 Up 0.089764564 Gm12070 glyceraldehyde-3-phosphate dehydrogenase pseudogene K00134|1|0.0|668|mmu:14433|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] - - - - 19879 3433.57 0.186666667 0.196666667 0.075288127 Up 0.089764564 Slc22a8 "solute carrier family 22 (organic anion transporter), member 8" "K08205|1|0.0|966|mmu:19879|MFS transporter, OCT family, solute carrier family 22 (organic anion transporter), member 8" GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane GO:0015301//anion:anion antiporter activity;GO:0015101//organic cation transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0015101//organic cation transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0015101//organic cation transmembrane transporter activity GO:0042939//tripeptide transport;GO:0044763;GO:0010243//response to organonitrogen compound;GO:0006811//ion transport;GO:0042939//tripeptide transport;GO:0044763;GO:0010243//response to organonitrogen compound;GO:0006811//ion transport;GO:0042939//tripeptide transport;GO:0044763;GO:0010243//response to organonitrogen compound;GO:0006811//ion transport gi|257467527|ref|NP_112471.3|/0/solute carrier family 22 member 8 [Mus musculus] 320840 5002 0.22 0.233333333 0.084888898 Up 0.089764564 Negr1 neuronal growth regulator 1 K06775|1|8e-172|606|mmu:320840|neuronal growth regulator 1 GO:0044297//cell body;GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0044297//cell body;GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding GO:0022610;GO:0022610 gi|84875493|ref|NP_001034183.1|/0/neuronal growth regulator 1 isoform a precursor [Mus musculus] 94216 6648 0.116666667 0.11 -0.084888898 Down 0.089764564 Col4a6 "collagen, type IV, alpha 6" "K06237|1|0.0|2297|mmu:94216|collagen, type IV, alpha" - - - gi|176866126|ref|NP_444415.2|/0/collagen alpha-6(IV) chain precursor [Mus musculus] 211378 2638 0.123333333 0.116666667 -0.080170349 Down 0.089764564 6720489N17Rik RIKEN cDNA 6720489N17 gene K09228|1|0.0|660|mmu:380850|KRAB domain-containing zinc finger protein - - - gi|242332534|ref|NP_001156382.1|/0/uncharacterized protein LOC100041979 [Mus musculus] 224014 8324 1.963333333 1.986666667 0.017044697 Up 0.089454286 Fgd4 "FYVE, RhoGEF and PH domain containing 4" "K05723|1|0.0|1549|mmu:224014|FYVE, RhoGEF and PH domain containing 4" GO:0031252//cell leading edge;GO:0005856//cytoskeleton;GO:0042995//cell projection;GO:0031252//cell leading edge;GO:0005856//cytoskeleton;GO:0042995//cell projection;GO:0031252//cell leading edge;GO:0005856//cytoskeleton;GO:0042995//cell projection GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0003779//actin binding;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0003779//actin binding;GO:0043169//cation binding;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0003779//actin binding;GO:0043169//cation binding;GO:0008289//lipid binding GO:0007266//Rho protein signal transduction;GO:0022604//regulation of cell morphogenesis;GO:0030031//cell projection assembly;GO:0000187//activation of MAPK activity;GO:0007266//Rho protein signal transduction;GO:0022604//regulation of cell morphogenesis;GO:0030031//cell projection assembly;GO:0000187//activation of MAPK activity;GO:0007266//Rho protein signal transduction;GO:0022604//regulation of cell morphogenesis;GO:0030031//cell projection assembly;GO:0000187//activation of MAPK activity "gi|568995104|ref|XP_006522086.1|/0/PREDICTED: FYVE, RhoGEF and PH domain-containing protein 4 isoform X2 [Mus musculus]" 57908 11314.01 1.373333333 1.35 -0.024722429 Down 0.089454286 Zfp318 zinc finger protein 318 - - - - gi|157823950|ref|NP_997554.2|/0/zinc finger protein 318 isoform 1 [Mus musculus] 71310 5864 1.22 1.236666667 0.019575538 Up 0.089454286 Tbc1d9 "TBC1 domain family, member 9" K19951|1|0.0|1707|mmu:71310|TBC1 domain family member 9 - - - - 11434 1378 1.426666667 1.45 0.023404604 Up 0.089454286 Acr acrosin prepropeptide K01317|1|0.0|677|mmu:11434|acrosin [EC:3.4.21.10] GO:0001669//acrosomal vesicle;GO:0032991//macromolecular complex;GO:0001669//acrosomal vesicle;GO:0032991//macromolecular complex;GO:0001669//acrosomal vesicle;GO:0032991//macromolecular complex;GO:0001669//acrosomal vesicle;GO:0032991//macromolecular complex;GO:0001669//acrosomal vesicle;GO:0032991//macromolecular complex "GO:0004175//endopeptidase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0048029//monosaccharide binding;GO:0004175//endopeptidase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0048029//monosaccharide binding;GO:0004175//endopeptidase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0048029//monosaccharide binding;GO:0004175//endopeptidase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0048029//monosaccharide binding;GO:0004175//endopeptidase activity;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0048029//monosaccharide binding" GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0045762//positive regulation of adenylate cyclase activity;GO:0035036//sperm-egg recognition;GO:0009725//response to hormone;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0045762//positive regulation of adenylate cyclase activity;GO:0035036//sperm-egg recognition;GO:0009725//response to hormone;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0045762//positive regulation of adenylate cyclase activity;GO:0035036//sperm-egg recognition;GO:0009725//response to hormone;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0045762//positive regulation of adenylate cyclase activity;GO:0035036//sperm-egg recognition;GO:0009725//response to hormone;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0045762//positive regulation of adenylate cyclase activity;GO:0035036//sperm-egg recognition;GO:0009725//response to hormone gi|7304853|ref|NP_038483.1|/0/acrosin isoform 1 precursor [Mus musculus] 100503272 563.95 1.026666667 1.01 -0.023612557 Down 0.089454286 Gm11423 predicted gene 11423 - - - - gi|149053628|gb|EDM05445.1|/5.15718e-07/rCG33773 [Rattus norvegicus] 212198 2657 1.776666667 1.753333333 -0.019072733 Down 0.089454286 Wdr25 WD repeat domain 25 K12816|1|4e-38|162|aga:AgaP_AGAP008925|pre-mRNA-processing factor 17 - - - gi|226958523|ref|NP_808270.2|/0/WD repeat-containing protein 25 [Mus musculus] 320713 7420 1.203333333 1.22 0.019844811 Up 0.089454286 Mysm1 "myb-like, SWIRM and MPN domains 1" K11865|1|0.0|1594|mmu:320713|protein MYSM1 - - - - 69544 1806 1.57 1.586666667 0.015234514 Up 0.089454286 Wdr5b WD repeat domain 5B K14963|1|1e-177|625|mmu:69544|COMPASS component SWD3 - - - - 68010 5040 1.413333333 1.393333333 -0.020561322 Down 0.089454286 Bambi BMP and activin membrane-bound inhibitor K10162|1|9e-140|501|mmu:68010|BMP and activin membrane-bound inhibitor GO:0044424;GO:0031224//intrinsic component of membrane GO:0001664//G-protein coupled receptor binding "GO:0006351//transcription, DNA-templated;GO:0022604//regulation of cell morphogenesis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001837//epithelial to mesenchymal transition;GO:0043393//regulation of protein binding;GO:0008283//cell proliferation;GO:0048870//cell motility;GO:0035411//catenin import into nucleus;GO:0030177//positive regulation of Wnt signaling pathway" gi|33468995|ref|NP_080781.1|/7.54404e-139/BMP and activin membrane-bound inhibitor homolog precursor [Mus musculus] 244879 7347 1.296666667 1.28 -0.018663844 Down 0.089454286 Npat nuclear protein in the AT region K11321|1|8e-06|57.0|tad:TRIADDRAFT_58588|bromodomain-containing protein 8 - - - "gi|148693850|gb|EDL25797.1|/0/mCG5643, isoform CRA_a, partial [Mus musculus]" 67028 5842 1.286666667 1.303333333 0.01856776 Up 0.089454286 2610002M06Rik RIKEN cDNA 2610002M06 gene K12197|1|1e-81|308|ngi:103725346|charged multivesicular body protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding GO:0045184//establishment of protein localization;GO:0044763 gi|27229022|ref|NP_080197.2|/1.09864e-80/charged multivesicular body protein 1b-2 [Mus musculus] 245020 1596 1.546666667 1.566666667 0.018535951 Up 0.089454286 Slc35g2 "solute carrier family 35, member G2" - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|160333448|ref|NP_001094953.1|/0/solute carrier family 35 member G2 [Mus musculus] 109263 6585 1.813333333 1.793333333 -0.016000479 Down 0.089454286 Rlf rearranged L-myc fusion sequence K09229|1|4e-17|94.4|rro:104681430|KRAB and SCAN domains-containing zinc finger protein - - - gi|124486604|ref|NP_001074482.1|/0/zinc finger protein Rlf [Mus musculus] 26888 2424.19 1.36 1.38 0.021061616 Up 0.089454286 Clec4a2 "C-type lectin domain family 4, member a2" K10057|1|4e-128|461|mmu:26888|C-type lectin domain family 4 member A;K17514|5|1e-74|284|mmu:69810|C-type lectin domain family 6 member A - - - - 59056 4317 1.853333333 1.876666667 0.018050039 Up 0.089454286 Evc Ellis van Creveld gene syndrome K19605|1|0.0|1565|mmu:59056|ellis van creveld syndrome protein 1 GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle - GO:0007224//smoothened signaling pathway;GO:0001501//skeletal system development;GO:0048513//animal organ development gi|269784715|ref|NP_067267.2|/0/ellis-van Creveld syndrome protein homolog [Mus musculus] 333883 796 1.423333333 1.443333333 0.020130955 Up 0.089454286 Cd59b CD59b antigen K04008|1|4e-66|253|mmu:333883|CD59 antigen GO:0046658//anchored component of plasma membrane;GO:0043209//myelin sheath;GO:0009986//cell surface;GO:0044421 - GO:0001525//angiogenesis;GO:0019835//cytolysis;GO:0001818//negative regulation of cytokine production;GO:0009968//negative regulation of signal transduction;GO:0006915//apoptotic process;GO:0001905;GO:0002698;GO:0002673//regulation of acute inflammatory response;GO:0042098//T cell proliferation gi|568917609|ref|XP_006499864.1|/2.30198e-68/PREDICTED: CD59B glycoprotein isoform X2 [Mus musculus] 102465606 80 1.09 1.106666667 0.021892606 Up 0.089454286 Mir6973b microRNA 6973b - - - - - 14234 2739 1.233333333 1.253333333 0.023207391 Up 0.089454286 Foxc2 forkhead box C2 K09396|1|0.0|784|mmu:14234|forkhead box protein C - - - gi|159032068|ref|NP_038547.2|/0/forkhead box protein C2 [Mus musculus] 57745 3507 1.156666667 1.14 -0.020939338 Down 0.089454286 Zfp112 zinc finger protein 112 K09228|1|0.0|1875|mmu:57745|KRAB domain-containing zinc finger protein - - - gi|113865973|ref|NP_067282.2|/0/zinc finger protein 112 [Mus musculus] 56306 2640 1.003333333 0.986666667 -0.024166311 Down 0.089454286 Fam60a "family with sequence similarity 60, member A" - - - - gi|1575505|gb|AAB09547.1|/1.04656e-132/Tera [Mus musculus] 70945 4633.22 1.233333333 1.25 0.019365325 Up 0.089454286 Mmrn1 multimerin 1 K11499|1|3e-15|87.8|myd:102773103|centromere protein F;K20478|3|8e-15|86.3|asn:102374600|golgin subfamily B member 1 - - - gi|254588077|ref|NP_001156979.1|/0/multimerin-1 isoform b precursor [Mus musculus] 100125931 3781 1.59 1.613333333 0.021017781 Up 0.089454286 Phtf1os "putative homeodomain transcription factor 1, opposite strand" - - - - gi|26341994|dbj|BAC34659.1|/3.33626e-56/unnamed protein product [Mus musculus] 76794 888 1.443333333 1.46 0.016563845 Up 0.089454286 Man2c1os "mannosidase, alpha, class 2C, member 1, opposite strand" K01191|1|6e-21|103|cge:100761822|alpha-mannosidase [EC:3.2.1.24] - - - - 27494 6974 1.543333333 1.52 -0.021978369 Down 0.089454286 Amot angiomotin K16819|1|0.0|1468|mmu:27494|angiomotin - - - gi|590121980|ref|NP_695231.3|/0/angiomotin isoform 1 [Mus musculus] 68628 1866 1.533333333 1.51 -0.022122811 Down 0.089454286 Fbxw9 F-box and WD-40 domain protein 9 K10265|1|0.0|868|mmu:68628|F-box and WD-40 domain protein 9 - - - gi|124248556|ref|NP_081067.2|/0/F-box/WD repeat-containing protein 9 [Mus musculus] 13998 8061 1.03 1.013333333 -0.023535514 Down 0.089454286 Fgd6 "FYVE, RhoGEF and PH domain containing 6" "K05724|1|0.0|2559|mmu:13998|FYVE, RhoGEF and PH domain containing 5/6" - - - - 12363 1443 1.513333333 1.493333333 -0.019193565 Down 0.089454286 Casp4 "caspase 4, apoptosis-related cysteine peptidase" K12808|1|0.0|765|mmu:12363|caspase 11 [EC:3.4.22.64];K04394|2|0.0|683|rno:114555|caspase 4 [EC:3.4.22.57] GO:0032991//macromolecular complex;GO:0044297//cell body;GO:0042995//cell projection GO:0004175//endopeptidase activity;GO:0005515//protein binding GO:0012502//induction of programmed cell death;GO:0006952//defense response;GO:0006915//apoptotic process;GO:0019538//protein metabolic process gi|157951738|ref|NP_031635.2|/0/caspase-4 precursor [Mus musculus] 70930 4651.13 2.056666667 2.033333333 -0.016461247 Down 0.089454286 Nol8 nucleolar protein 8 - GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0016049//cell growth;GO:0006259//DNA metabolic process;GO:0042254//ribosome biogenesis;GO:0016049//cell growth;GO:0006259//DNA metabolic process;GO:0042254//ribosome biogenesis;GO:0016049//cell growth;GO:0006259//DNA metabolic process;GO:0042254//ribosome biogenesis gi|406353182|ref|NP_001258326.1|/0/nucleolar protein 8 [Mus musculus] 17951 5368 1.216666667 1.233333333 0.019628807 Up 0.089454286 Naip5 "NLR family, apoptosis inhibitory protein 5" K12807|1|0.0|2749|mmu:17951|baculoviral IAP repeat-containing protein 1 GO:0043234//protein complex;GO:0044464 GO:0043169//cation binding;GO:0032550 GO:0042742//defense response to bacterium;GO:0009581;GO:0012501//programmed cell death gi|124107602|ref|NP_035000.2|/0/baculoviral IAP repeat-containing protein 1e [Mus musculus] 269788 4782 0.13 0.136666667 0.072149786 Up 0.089294445 Lhfpl4 lipoma HMGIC fusion partner-like protein 4 - GO:0031224//intrinsic component of membrane - - gi|60360114|dbj|BAD90276.1|/1.029e-145/mKIAA4027 protein [Mus musculus] 319552 1536 0.133333333 0.14 0.070389328 Up 0.089294445 Spx spexin hormone - GO:0031981//nuclear lumen - - gi|393715075|ref|NP_001229274.1|/3.72166e-39/spexin precursor [Mus musculus] 114304 4565 0.256666667 0.27 0.073063462 Up 0.089294445 Slc28a3 "solute carrier family 28 (sodium-coupled nucleoside transporter), member 3" K11536|1|0.0|1322|mmu:114304|pyrimidine nucleoside transport protein GO:0016021//integral component of membrane GO:0005345//purine nucleobase transmembrane transporter activity;GO:0005415//nucleoside:sodium symporter activity;GO:0036094//small molecule binding GO:0006814//sodium ion transport;GO:0015851//nucleobase transport;GO:0001894//tissue homeostasis;GO:0015858//nucleoside transport;GO:0072530//purine-containing compound transmembrane transport gi|91598783|ref|NP_071712.3|/0/solute carrier family 28 member 3 [Mus musculus] 56811 3705 0.133333333 0.126666667 -0.074000581 Down 0.089294445 Dkk2 dickkopf WNT signaling pathway inhibitor 2 K02165|1|6e-157|558|mmu:56811|dickkopf - - - - 22787 2200 0.2 0.21 0.070389328 Up 0.089294445 Zp2 zona pellucida glycoprotein 2 K19927|1|0.0|1391|mmu:22787|zona pellucida sperm-binding protein 2 "GO:0031224//intrinsic component of membrane;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005770//late endosome;GO:0031012//extracellular matrix" GO:0019899//enzyme binding GO:0035036//sperm-egg recognition;GO:0007340//acrosome reaction;GO:0007343//egg activation;GO:0000041//transition metal ion transport;GO:0015031//protein transport gi|6756081|ref|NP_035905.1|/0/zona pellucida sperm-binding protein 2 precursor [Mus musculus] 211232 2779 0.206666667 0.216666667 0.068171503 Up 0.089294445 Cpne9 copine family member IX K11348|1|9e-35|148|apla:101800649|bromodomain and PHD finger-containing protein 1;K06491|3|7e-10|68.9|cin:100183448|neural cell adhesion molecule;K19902|4|2e-08|64.3|dre:559637|synaptotagmin-2;K19906|5|2e-07|61.2|sko:100376714|synaptotagmin-6 - - - gi|589994471|ref|XP_006997872.1|/0/PREDICTED: copine-9-like [Peromyscus maniculatus bairdii] 59012 3083 0.193333333 0.203333333 0.072756342 Up 0.089294445 Moxd1 "monooxygenase, DBH-like 1" "K15266|1|8e-104|381|bfo:BRAFLDRAFT_125270|dimethyladenosine transferase 1, mitochondrial [EC:2.1.1.-];K00503|3|2e-82|310|xtr:100492247|dopamine beta-monooxygenase [EC:1.14.17.1]" GO:0031090//organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane "GO:0046914//transition metal ion binding;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen" GO:0009712//catechol-containing compound metabolic process gi|31981183|ref|NP_067484.2|/0/DBH-like monooxygenase protein 1 precursor [Mus musculus] 66949 2920 0.286666667 0.273333333 -0.06871275 Down 0.089294445 Trim59 tripartite motif-containing 59 K12028|1|0.0|785|mmu:66949|tripartite motif-containing protein 59 GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|170295836|ref|NP_080139.3|/0/tripartite motif-containing protein 59 [Mus musculus] 207819 4594 0.286666667 0.273333333 -0.06871275 Down 0.089294445 4930539E08Rik RIKEN cDNA 4930539E08 gene - - - - "gi|148690646|gb|EDL22593.1|/0/RIKEN cDNA 4930539E08, isoform CRA_a, partial [Mus musculus]" 619314 1938 0.143333333 0.136666667 -0.06871275 Down 0.089294445 B020014A21Rik RIKEN cDNA B020014A21 gene K07986|1|6e-08|62.0|cge:103161647|UL16 binding protein - - - - 15438 2100 0.146666667 0.14 -0.067114196 Down 0.089294445 Hoxd9 homeobox D9 K09294|1|2e-107|392|mmu:15438|homeobox protein HoxA/B/C/D9 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity GO:0003002//regionalization;GO:0048732//gland development;GO:0001501//skeletal system development;GO:0007626//locomotory behavior;GO:0048562//embryonic organ morphogenesis;GO:0014706//striated muscle tissue development;GO:0048666//neuron development;GO:0006366//transcription from RNA polymerase II promoter;GO:0030326//embryonic limb morphogenesis gi|7305153|ref|NP_038583.1|/1.82337e-106/homeobox protein Hox-D9 [Mus musculus] 170676 6677 0.213333333 0.223333333 0.06608919 Up 0.089294445 Peg10 paternally expressed 10 "K10798|1|7e-15|87.0|dre:558045|poly [ADP-ribose] polymerase [EC:2.4.2.30];K08103|2|7e-09|67.0|ola:101158495|heparan sulfate 6-O-sulfotransferase HS6ST3 [EC:2.8.2.-];K18438|3|7e-07|60.5|gja:107119131|cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]" - - - gi|98985814|ref|NP_570947.2|/0/retrotransposon-derived protein PEG10 isoform 1 [Mus musculus] 71740 3509 0.253333333 0.266666667 0.074000581 Up 0.089294445 Pvrl4 nectin cell adhesion molecule 4 K06593|1|0.0|923|mmu:71740|poliovirus receptor-related 4 GO:0070161;GO:0031224//intrinsic component of membrane;GO:0070161;GO:0031224//intrinsic component of membrane - GO:0007155//cell adhesion;GO:0007155//cell adhesion gi|74196108|dbj|BAE32972.1|/0/unnamed protein product [Mus musculus] 78834 2486 3.603333333 3.636666667 0.013284579 Up 0.089012374 Zfp623 zinc finger protein 623 K09228|1|0.0|1063|mmu:78834|KRAB domain-containing zinc finger protein GO:0005622//intracellular GO:0005488//binding "GO:0006351//transcription, DNA-templated" gi|50510555|dbj|BAD32263.1|/0/mKIAA0628 protein [Mus musculus] 52635 5556 5.536666667 5.563333333 0.006931881 Up 0.089012374 Esyt2 extended synaptotagmin-like protein 2 K19513|1|6e-28|130|tsp:Tsp_01622|protein CLEC16A;K00923|2|2e-16|92.0|aqu:100639364|phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154];K17598|3|6e-15|87.0|mze:101481813|synaptotagmin-like protein;K19917|5|6e-14|83.6|nve:NEMVE_v1g206051|double C2-like domain-containing protein beta GO:0031224//intrinsic component of membrane - - gi|67782360|ref|NP_083007.2|/0/extended synaptotagmin-2 [Mus musculus] 71968 2382.98 3.56 3.59 0.012106603 Up 0.089012374 Wdr73 WD repeat domain 73 - - - - gi|254910981|ref|NP_082302.2|/0/WD repeat-containing protein 73 [Mus musculus] 140740 6058 6.72 6.686666667 -0.007174033 Down 0.089012374 Sec63 SEC63-like (S. cerevisiae) K09540|1|0.0|1374|mmu:140740|translocation protein SEC63 - - - - 68044 1330 5.816666667 5.843333333 0.00659896 Up 0.089012374 Chac2 "ChaC, cation transport regulator 2" K07232|1|5e-45|184|mdo:100032070|cation transport protein ChaC - - - gi|594591588|ref|NP_001277596.1|/7.10007e-94/putative glutathione-specific gamma-glutamylcyclotransferase 2 isoform 2 [Mus musculus] 69487 2732 6.52 6.55 0.006622942 Up 0.089012374 Ndufaf5 "NADH dehydrogenase (ubiquinone) complex I, assembly factor 5" K18162|1|0.0|677|mmu:69487|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 [EC:2.1.1.-] GO:0005743//mitochondrial inner membrane GO:0016741 GO:0010257//NADH dehydrogenase complex assembly;GO:0008152//metabolic process gi|166295190|ref|NP_081369.2|/0/NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 precursor [Mus musculus] 67948 4932 4.876666667 4.843333333 -0.009895067 Down 0.089012374 Fbxo28 F-box protein 28 K10306|1|1e-146|524|mmu:67948|F-box protein 28 - - - gi|74189538|dbj|BAE36778.1|/1.06481e-145/unnamed protein product [Mus musculus] 55948 1616 3.086666667 3.113333333 0.012410356 Up 0.089012374 Sfn stratifin K06644|1|8e-133|476|cjc:100408657|stratifin - - - - 212127 4322 4.72 4.693333333 -0.008173931 Down 0.089012374 Proser1 proline and serine rich 1 "K06568|1|3e-11|74.3|myb:102251906|mucin 1, transmembrane;K13909|5|4e-11|73.9|rro:104678567|mucin-7" - - - gi|30795245|ref|NP_775558.2|/0/proline and serine-rich protein 1 [Mus musculus] 71448 1151.73 7.303333333 7.336666667 0.006569661 Up 0.089012374 Tmem80 transmembrane protein 80 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|568952488|ref|XP_006536314.1|/3.11827e-54/PREDICTED: transmembrane protein 80 isoform X3 [Mus musculus] 320634 5198 3.833333333 3.863333333 0.011246705 Up 0.089012374 Ocrl oculocerebrorenal syndrome of Lowe K01099|1|0.0|1786|mmu:320634|inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36] GO:0031513//nonmotile primary cilium;GO:0030666//endocytic vesicle membrane;GO:0044431//Golgi apparatus part;GO:0030135//coated vesicle;GO:0005769//early endosome GO:0034593//phosphatidylinositol bisphosphate phosphatase activity;GO:0017048//Rho GTPase binding GO:0046474//glycerophospholipid biosynthetic process;GO:0043009//chordate embryonic development;GO:0046488//phosphatidylinositol metabolic process;GO:0010927 gi|46195807|ref|NP_796189.2|/0/inositol polyphosphate 5-phosphatase OCRL-1 [Mus musculus] 210029 2468 5.44 5.466666667 0.007054758 Up 0.089012374 Metrnl "meteorin, glial cell differentiation regulator-like" K00901|1|4e-43|179|bfo:BRAFLDRAFT_118688|diacylglycerol kinase (ATP) [EC:2.7.1.107] - - - gi|21450153|ref|NP_659046.1|/1.51093e-155/meteorin-like protein precursor [Mus musculus] 66296 3096.84 6.103333333 6.13 0.006289689 Up 0.089012374 Haus2 "HAUS augmin-like complex, subunit 2" K16585|1|4e-123|445|mmu:66296|HAUS augmin-like complex subunit 2 GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex;GO:0005815//microtubule organizing center;GO:0005875//microtubule associated complex - GO:0006461//protein complex assembly;GO:0031023//microtubule organizing center organization;GO:0000087//mitotic M phase;GO:0006461//protein complex assembly;GO:0031023//microtubule organizing center organization;GO:0000087//mitotic M phase;GO:0006461//protein complex assembly;GO:0031023//microtubule organizing center organization;GO:0000087//mitotic M phase gi|392339420|ref|XP_003753808.1|/1.69966e-94/PREDICTED: HAUS augmin-like complex subunit 2 isoform X1 [Rattus norvegicus] 67890 4887 5.25 5.28 0.008220507 Up 0.089012374 Ufm1 ubiquitin-fold modifier 1 K12162|1|4e-40|170|chx:102171888|ubiquitin-fold modifier 1 GO:0043231//intracellular membrane-bounded organelle - GO:0032446//protein modification by small protein conjugation gi|545541681|ref|XP_534489.3|/5.39506e-41/PREDICTED: ubiquitin-fold modifier 1 isoform X1 [Canis lupus familiaris] 329877 7793 3.356666667 3.383333333 0.011416044 Up 0.089012374 Dennd4c DENN/MADD domain containing 4C K20163|1|0.0|3537|mmu:329877|DENN domain-containing protein 4 GO:0012505//endomembrane system;GO:0031982//vesicle;GO:0016020//membrane;GO:0044424 GO:0005088//Ras guanyl-nucleotide exchange factor activity GO:0045184//establishment of protein localization gi|300863147|ref|NP_908976.1|/0/DENN domain-containing protein 4C [Mus musculus] 68304 3644 3.673333333 3.703333333 0.011734593 Up 0.089012374 Kdelc2 KDEL (Lys-Asp-Glu-Leu) containing 2 K13667|1|2e-34|150|crg:105327429|protein glucosyltransferase [EC:2.4.1.-] GO:0044432 - - gi|47078285|ref|NP_997610.1|/0/KDEL motif-containing protein 2 precursor [Mus musculus] 71718 3477.11 3.753333333 3.723333333 -0.011577642 Down 0.089012374 Telo2 telomere maintenance 2 K11137|1|0.0|1580|mmu:71718|telomere length regulation protein GO:0043234//protein complex;GO:0043232;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043232;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding;GO:0005515//protein binding GO:0009966//regulation of signal transduction;GO:0009966//regulation of signal transduction gi|12835850|dbj|BAB23388.1|/0/unnamed protein product [Mus musculus] 103135 4395.2 4.95 4.98 0.008717217 Up 0.089012374 Pan2 PAN2 poly(A) specific ribonuclease subunit K12571|1|0.0|2333|mmu:103135|PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule;GO:0043231//intracellular membrane-bounded organelle;GO:0035770//ribonucleoprotein granule GO:0016790//thiolester hydrolase activity;GO:0097159//organic cyclic compound binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0016790//thiolester hydrolase activity;GO:0097159//organic cyclic compound binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0016790//thiolester hydrolase activity;GO:0097159//organic cyclic compound binding;GO:0000175//3'-5'-exoribonuclease activity "GO:0019941//modification-dependent protein catabolic process;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0019941//modification-dependent protein catabolic process;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0019941//modification-dependent protein catabolic process;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" gi|356640190|ref|NP_001239256.1|/0/PAB-dependent poly(A)-specific ribonuclease subunit PAN2 isoform 3 [Mus musculus] 83815 1442 3.013333333 3.04 0.012711052 Up 0.089012374 Cenpq centromere protein Q K11509|1|6e-137|489|mmu:83815|centromere protein Q GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0005694//chromosome - GO:0007067//mitotic nuclear division;GO:0043486//histone exchange gi|13994186|ref|NP_114069.1|/5.13779e-136/centromere protein Q [Mus musculus] 74479 2542.43 3.576666667 3.55 -0.010796646 Down 0.089012374 Snx11 sorting nexin 11 K17924|1|4e-120|435|mmu:74479|sorting nexin-10/11 - GO:0005543//phospholipid binding;GO:0005543//phospholipid binding GO:0045184//establishment of protein localization;GO:0044763;GO:0045184//establishment of protein localization;GO:0044763 gi|22094999|ref|NP_083241.1|/3.05609e-119/sorting nexin-11 [Mus musculus] 140579 4600 6.953333333 6.986666667 0.006899559 Up 0.089012374 Elmo2 engulfment and cell motility 2 K18985|1|0.0|1395|cge:100769563|engulfment and cell motility protein 2 GO:0043232;GO:0044444//cytoplasmic part;GO:0043232;GO:0044444//cytoplasmic part;GO:0043232;GO:0044444//cytoplasmic part;GO:0043232;GO:0044444//cytoplasmic part GO:0019904//protein domain specific binding;GO:0005102//receptor binding;GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0005102//receptor binding;GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0005102//receptor binding;GO:0008289//lipid binding;GO:0019904//protein domain specific binding;GO:0005102//receptor binding GO:0006935//chemotaxis;GO:0012501//programmed cell death;GO:0006897//endocytosis;GO:0006935//chemotaxis;GO:0012501//programmed cell death;GO:0006897//endocytosis;GO:0006935//chemotaxis;GO:0012501//programmed cell death;GO:0006897//endocytosis;GO:0006935//chemotaxis;GO:0012501//programmed cell death;GO:0006897//endocytosis gi|46877043|ref|NP_525026.2|/0/engulfment and cell motility protein 2 isoform 3 [Mus musculus] 67249 2688 6 5.97 -0.007231569 Down 0.089012374 Tbc1d19 "TBC1 domain family, member 19" - GO:0044464 - - "gi|148705735|gb|EDL37682.1|/0/TBC1 domain family, member 19, isoform CRA_a [Mus musculus]" 217119 3424 6.003333333 5.976666667 -0.006422693 Down 0.089012374 Xylt2 xylosyltransferase II K00771|1|0.0|1658|mmu:217119|protein xylosyltransferase [EC:2.4.2.26] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0035252//UDP-xylosyltransferase activity GO:0006024//glycosaminoglycan biosynthetic process;GO:0030166//proteoglycan biosynthetic process gi|165932343|ref|NP_665827.2|/0/xylosyltransferase 2 [Mus musculus] 69562 7052.54 5.16 5.186666667 0.007436589 Up 0.089012374 Cdk13 cyclin-dependent kinase 13 K08819|1|0.0|1618|pps:100987832|cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23] GO:0016604//nuclear body;GO:0000307//cyclin-dependent protein kinase holoenzyme complex GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity "GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0048534//hematopoietic or lymphoid organ development;GO:0007067//mitotic nuclear division;GO:0000398//mRNA splicing, via spliceosome" gi|124486698|ref|NP_001074527.1|/0/cyclin-dependent kinase 13 isoform 1 [Mus musculus] 234362 2464 3.143333333 3.113333333 -0.013835221 Down 0.089012374 Zfp868 zinc finger protein 868 K09228|1|0.0|888|mmu:234362|KRAB domain-containing zinc finger protein GO:0044464;GO:0044464 GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148696795|gb|EDL28742.1|/0/mCG58990, isoform CRA_a, partial [Mus musculus]" 100039257 1447 6.63 6.603333333 -0.005814396 Down 0.089012374 Tmem254b transmembrane protein 254b - GO:0043231//intracellular membrane-bounded organelle - GO:0002761//regulation of myeloid leukocyte differentiation;GO:0044710 gi|21313632|ref|NP_079587.1|/2.90185e-70/transmembrane protein 254 isoform 2 [Mus musculus] 67647 4035 8.216666667 8.186666667 -0.005277086 Down 0.089012374 4930523C07Rik RIKEN cDNA 4930523C07 gene - - - - "gi|148707399|gb|EDL39346.1|/6.12307e-63/mCG145053, isoform CRA_b, partial [Mus musculus]" 12370 2461.33 4.476666667 4.443333333 -0.010782524 Down 0.089012374 Casp8 caspase 8 K04398|1|0.0|952|mmu:12370|caspase 8 [EC:3.4.22.61] GO:0031981//nuclear lumen;GO:0005815//microtubule organizing center;GO:0042995//cell projection;GO:0030686//90S preribosome;GO:0031264//death-inducing signaling complex;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0005815//microtubule organizing center;GO:0042995//cell projection;GO:0030686//90S preribosome;GO:0031264//death-inducing signaling complex;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0005815//microtubule organizing center;GO:0042995//cell projection;GO:0030686//90S preribosome;GO:0031264//death-inducing signaling complex;GO:0044444//cytoplasmic part GO:0004175//endopeptidase activity;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0019899//enzyme binding;GO:0004175//endopeptidase activity;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0019899//enzyme binding;GO:0004175//endopeptidase activity;GO:0032813//tumor necrosis factor receptor superfamily binding;GO:0019899//enzyme binding GO:0007166//cell surface receptor signaling pathway;GO:0009612//response to mechanical stimulus;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0009636//response to toxic substance;GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0034097//response to cytokine;GO:0051259//protein oligomerization;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010038//response to metal ion;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0097305//response to alcohol;GO:0006950//response to stress;GO:0006508//proteolysis;GO:0002237//response to molecule of bacterial origin;GO:0001838//embryonic epithelial tube formation;GO:0007166//cell surface receptor signaling pathway;GO:0009612//response to mechanical stimulus;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0009636//response to toxic substance;GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0034097//response to cytokine;GO:0051259//protein oligomerization;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010038//response to metal ion;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0097305//response to alcohol;GO:0006950//response to stress;GO:0006508//proteolysis;GO:0002237//response to molecule of bacterial origin;GO:0001838//embryonic epithelial tube formation;GO:0007166//cell surface receptor signaling pathway;GO:0009612//response to mechanical stimulus;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0009636//response to toxic substance;GO:0043627//response to estrogen;GO:0006915//apoptotic process;GO:0034097//response to cytokine;GO:0051259//protein oligomerization;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0010038//response to metal ion;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0097305//response to alcohol;GO:0006950//response to stress;GO:0006508//proteolysis;GO:0002237//response to molecule of bacterial origin;GO:0001838//embryonic epithelial tube formation gi|485050304|ref|NP_001264855.1|/0/caspase-8 isoform 2 [Mus musculus] 225523 4572 6.666666667 6.7 0.007195501 Up 0.089012374 Cep120 centrosomal protein 120 K16459|1|0.0|1771|mmu:225523|centrosomal protein CEP120 - - - "gi|148677957|gb|EDL09904.1|/0/expressed sequence AU016693, isoform CRA_c, partial [Mus musculus]" 243272 10071 4.76 4.793333333 0.010067696 Up 0.089012374 Sbno1 strawberry notch homolog 1 (Drosophila) - - - "GO:0006351//transcription, DNA-templated" gi|124487087|ref|NP_001074672.1|/0/protein strawberry notch homolog 1 [Mus musculus] 26562 3701 9.376666667 9.343333333 -0.005137808 Down 0.089012374 Ncdn neurochondrin K09179|1|3e-06|57.4|mcc:100428085|transcription factor AP-2 epsilon GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0044297//cell body;GO:0044444//cytoplasmic part - GO:0001894//tissue homeostasis;GO:0030030//cell projection organization;GO:0048167//regulation of synaptic plasticity gi|172072590|ref|NP_036116.3|/0/neurochondrin [Mus musculus] 18786 6815 6.863333333 6.83 -0.007023846 Down 0.089012374 Plaa "phospholipase A2, activating protein" K14018|1|0.0|1590|mmu:18786|phospholipase A-2-activating protein GO:0031988//membrane-bounded vesicle GO:0016004//phospholipase activator activity GO:0006952//defense response;GO:0044093 "gi|148698991|gb|EDL30938.1|/0/phospholipase A2, activating protein, isoform CRA_c, partial [Mus musculus]" 140559 2280 6.71 6.68 -0.006464664 Down 0.089012374 Igsf8 "immunoglobulin superfamily, member 8" "K06730|1|0.0|1138|mmu:140559|immunoglobulin superfamily, member 8" - - - - 70238 4468 4.076666667 4.106666667 0.010577852 Up 0.089012374 Rnf168 ring finger protein 168 K11997|1|7e-06|56.6|bfo:BRAFLDRAFT_79377|tripartite motif-containing protein 2/3;K12015|2|7e-06|56.6|dre:100137104|tripartite motif-containing protein 39 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0043234//protein complex GO:0031593//polyubiquitin binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0003682//chromatin binding GO:0000209//protein polyubiquitination;GO:0010390//histone monoubiquitination;GO:0033522//histone H2A ubiquitination;GO:0006414//translational elongation;GO:0009314//response to radiation;GO:0019941//modification-dependent protein catabolic process;GO:0002204//somatic recombination of immunoglobulin genes involved in immune response;GO:0006281//DNA repair "gi|148665366|gb|EDK97782.1|/0/ring finger protein 168, isoform CRA_b, partial [Mus musculus]" 213439 5211 0.313333333 0.3 -0.062735755 Down 0.088598669 Gpr174 G protein-coupled receptor 174 K08391|1|0.0|694|mmu:213439|G protein-coupled receptor 174 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0001608;GO:0001608;GO:0001608 GO:0035588;GO:0035588;GO:0035588 gi|569009929|ref|XP_006527994.1|/0/PREDICTED: probable G-protein coupled receptor 174 isoform X1 [Mus musculus] 12525 3099 0.316666667 0.303333333 -0.062060968 Down 0.088598669 Cd8a "CD8 antigen, alpha chain" "K06458|1|2e-128|463|mmu:12525|CD8A antigen, alpha polypeptide" GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface GO:0019900//kinase binding;GO:0042802//identical protein binding;GO:0019900//kinase binding;GO:0042802//identical protein binding GO:0006952//defense response;GO:0030217//T cell differentiation;GO:0002449;GO:0019722//calcium-mediated signaling;GO:0006952//defense response;GO:0030217//T cell differentiation;GO:0002449;GO:0019722//calcium-mediated signaling gi|124487437|ref|NP_001074579.1|/9.43474e-116/T-cell surface glycoprotein CD8 alpha chain isoform 1 precursor [Mus musculus] 353208 1779 0.153333333 0.16 0.061400545 Up 0.088598669 Zfp931 zinc finger protein 931 K09228|1|0.0|582|mmu:626832|KRAB domain-containing zinc finger protein - - - "gi|150010536|ref|NP_001092778.1|/0/KRAB box and zinc finger, C2H2 type domain containing isoform 1 [Mus musculus]" 100504375 2884 0.24 0.23 -0.061400545 Down 0.088598669 Gm15880 predicted gene 15880 - - - - - 381334 2846 0.173333333 0.166666667 -0.056583528 Down 0.088598669 Gal3st2 galactose-3-O-sulfotransferase 2 K09675|1|0.0|724|mmu:381334|galactose-3-O-sulfotransferase 2 [EC:2.8.2.-] - GO:0008146//sulfotransferase activity GO:0006790//sulfur compound metabolic process gi|224922779|ref|NP_955398.3|/0/galactose-3-O-sulfotransferase 2 [Mus musculus] 114654 605 0.176666667 0.17 -0.055495113 Down 0.088598669 Ly6g6d "lymphocyte antigen 6 complex, locus G6D" K06846|1|7e-68|258|mmu:114654|lymphocyte antigen 6 complex locus protein D/E/G6/H GO:0031224//intrinsic component of membrane;GO:0044464 - - gi|15638950|ref|NP_258439.1|/5.11991e-67/lymphocyte antigen 6 complex locus protein G6d precursor [Mus musculus] 106763 6959 0.166666667 0.173333333 0.056583528 Up 0.088598669 Ttbk1 tau tubulin kinase 1 K08815|1|0.0|2012|mmu:106763|tau tubulin kinase [EC:2.7.11.26] - - - gi|242247093|ref|NP_001156336.1|/0/tau-tubulin kinase 1 [Mus musculus] 11899 7217 0.17 0.176666667 0.055495113 Up 0.088598669 Astn1 astrotactin 1 K14480|1|2e-08|65.5|oas:105606035|apolipoprotein L;K17307|2|2e-06|58.9|dse:Dsec_GM14855|fibulin 1/2 GO:0009986//cell surface;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0009986//cell surface;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding GO:0016337//single organismal cell-cell adhesion;GO:0044708//single-organism behavior;GO:0016477//cell migration;GO:0016337//single organismal cell-cell adhesion;GO:0044708//single-organism behavior;GO:0016477//cell migration gi|46488926|ref|NP_031521.2|/0/astrotactin-1 isoform 2 precursor [Mus musculus] 19419 5155 0.153333333 0.146666667 -0.064130337 Down 0.088598669 Rasgrp1 RAS guanyl releasing protein 1 K04350|1|0.0|1587|mmu:19419|RAS guanyl-releasing protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0046872//metal ion binding GO:0002279;GO:0051648//vesicle localization;GO:0044707;GO:0048869//cellular developmental process;GO:0006954//inflammatory response gi|7242201|ref|NP_035376.1|/0/RAS guanyl-releasing protein 1 [Mus musculus] 623121 2635 0.17 0.163333333 -0.057715498 Down 0.088598669 Pydc4 pyrin domain containing 4 - - - - gi|293629249|ref|NP_001170820.1|/3.12647e-61/uncharacterized protein LOC623121 [Mus musculus] 72446 4159 0.226666667 0.236666667 0.062284278 Up 0.088598669 Prr5l proline rich 5 like K20411|1|1e-51|208|cjo:107317477|proline-rich protein 5 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - - gi|568918526|ref|XP_006500299.1|/0/PREDICTED: proline-rich protein 5-like isoform X2 [Mus musculus] 83925 10026.58 0.303333333 0.29 -0.064851144 Down 0.088598669 Trps1 trichorhinophalangeal syndrome I (human) K09220|1|1e-15|90.5|spu:100892885|IKAROS family zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0002062//chondrocyte differentiation;GO:0006351//transcription, DNA-templated;GO:0002062//chondrocyte differentiation;GO:0006351//transcription, DNA-templated;GO:0002062//chondrocyte differentiation;GO:0006351//transcription, DNA-templated" gi|882157900|ref|NP_001297410.1|/0/zinc finger transcription factor Trps1 isoform 1 [Mus musculus] 224044 2735 0.32 0.306666667 -0.061400545 Down 0.088598669 Cyp2ab1 "cytochrome P450, family 2, subfamily ab, polypeptide 1" "K17857|1|4e-163|578|mmu:224044|cytochrome P450, family 2, subfamily P" - - - "gi|148665147|gb|EDK97563.1|/0/hypothetical protein F730023N20, isoform CRA_a [Mus musculus]" 22779 9457 0.243333333 0.233333333 -0.060541542 Down 0.088598669 Ikzf2 IKAROS family zinc finger 2 K09220|1|0.0|1089|cge:100760184|IKAROS family zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0046983//protein dimerization activity GO:0006366//transcription from RNA polymerase II promoter gi|354477266|ref|XP_003500843.1|/0/PREDICTED: zinc finger protein Helios isoform X2 [Cricetulus griseus] 236690 3635 0.31 0.296666667 -0.06342538 Down 0.088598669 Nyx nyctalopin K08129|1|0.0|705|mmu:236690|nyctalopin GO:0044464 - GO:0050953//sensory perception of light stimulus gi|27734150|ref|NP_775591.1|/0/nyctalopin precursor [Mus musculus] 18209 4912 0.223333333 0.233333333 0.063193826 Up 0.088598669 Ntn3 netrin 3 K06844|1|0.0|1000|mmu:18209|netrin 3 GO:0043231//intracellular membrane-bounded organelle;GO:0031012//extracellular matrix GO:0005515//protein binding GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006935//chemotaxis gi|6754904|ref|NP_035077.1|/0/netrin-3 precursor [Mus musculus] 381924 3975 0.176666667 0.17 -0.055495113 Down 0.088598669 Itgad "integrin, alpha D" K06594|1|0.0|2360|mmu:381924|integrin alpha D GO:0005887//integral component of plasma membrane GO:0043169//cation binding;GO:0046983//protein dimerization activity GO:0007166//cell surface receptor signaling pathway;GO:0042098//T cell proliferation;GO:0022610 gi|294997269|ref|NP_001025043.3|/0/integrin alpha-D precursor [Mus musculus] 218314 3909 0.193333333 0.2 0.0489096 Up 0.087912295 Zfp595 zinc finger protein 595 K09228|1|0.0|1367|mmu:218314|KRAB domain-containing zinc finger protein - GO:0046872//metal ion binding - "gi|148678369|gb|EDL10316.1|/0/mCG144600, partial [Mus musculus]" 58186 2560 0.276666667 0.286666667 0.051225323 Up 0.087912295 Rad18 RAD18 E3 ubiquitin protein ligase K10627|1|0.0|892|mmu:58186|E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0000803//sex chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0000803//sex chromosome GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0043130//ubiquitin binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003824//catalytic activity;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0043130//ubiquitin binding;GO:0044389//ubiquitin-like protein ligase binding;GO:0003824//catalytic activity GO:0009416//response to light stimulus;GO:0033554//cellular response to stress;GO:0000018//regulation of DNA recombination;GO:0048232//male gamete generation;GO:0009416//response to light stimulus;GO:0033554//cellular response to stress;GO:0000018//regulation of DNA recombination;GO:0048232//male gamete generation gi|267844908|ref|NP_067360.2|/0/E3 ubiquitin-protein ligase RAD18 isoform 2 [Mus musculus] 67752 1458 0.203333333 0.196666667 -0.048094288 Down 0.087912295 Ppp1r32 "protein phosphatase 1, regulatory subunit 32" K17571|1|0.0|893|mmu:67752|protein phosphatase 1 regulatory subunit 32 - GO:0019899//enzyme binding - "gi|148709409|gb|EDL41355.1|/0/RIKEN cDNA 4930579J09, isoform CRA_b, partial [Mus musculus]" 16494 5853 0.356666667 0.343333333 -0.054966459 Down 0.087912295 Kcna6 "potassium voltage-gated channel, shaker-related, subfamily, member 6" K04879|1|0.0|822|mmu:16494|potassium voltage-gated channel Shaker-related subfamily A member 6 GO:0005887//integral component of plasma membrane GO:0005267//potassium channel activity GO:0051259//protein oligomerization;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|7305201|ref|NP_038596.1|/0/potassium voltage-gated channel subfamily A member 6 [Mus musculus] 70100 2917 0.353333333 0.366666667 0.053439259 Up 0.087912295 2310015D24Rik RIKEN cDNA 2310015D24 gene - - - - gi|74203772|dbj|BAE23109.1|/8.77453e-65/unnamed protein product [Mus musculus] 17756 5445 0.313333333 0.303333333 -0.046794211 Down 0.087912295 Map2 microtubule-associated protein 2 K10430|1|0.0|657|cge:100756420|microtubule-associated protein 2 GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton;GO:0030425//dendrite;GO:0031981//nuclear lumen;GO:0044297//cell body;GO:0005783//endoplasmic reticulum GO:0001948//glycoprotein binding;GO:0015631//tubulin binding GO:0006468//protein phosphorylation;GO:0016358//dendrite development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0043627//response to estrogen;GO:0021953//central nervous system neuron differentiation gi|890810631|ref|NP_001297563.1|/0/microtubule-associated protein 2 isoform 3 [Mus musculus] 432770 2981 0.356666667 0.37 0.05294888 Up 0.087912295 Rslcan18 regulator of sex-limitation candidate 18 K09228|1|0.0|667|cge:100752468|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|365812506|ref|NP_001242981.1|/0/regulator of sex-limitation candidate 18 [Mus musculus] 233781 3070 0.19 0.183333333 -0.051530301 Down 0.087912295 Xylt1 xylosyltransferase 1 K00771|1|0.0|1776|mmu:233781|protein xylosyltransferase [EC:2.4.2.26] - - - - 64706 7842 0.413333333 0.4 -0.047305715 Down 0.087912295 Scube1 "signal peptide, CUB domain, EGF-like 1" K06825|1|2e-91|341|sko:100374579|fibrillin 1 - - - - 237711 8080 0.356666667 0.37 0.05294888 Up 0.087912295 Eml6 echinoderm microtubule associated protein like 6 K18598|1|0.0|3891|mmu:237711|echinoderm microtubule-associated protein-like 6 GO:0015630//microtubule cytoskeleton - - gi|127140886|ref|NP_666128.2|/0/echinoderm microtubule-associated protein-like 6 [Mus musculus] 12545 2851 0.373333333 0.386666667 0.050626073 Up 0.087912295 Cdc7 cell division cycle 7 (S. cerevisiae) K02214|1|0.0|1130|mmu:12545|cell division control protein 7 [EC:2.7.11.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity;GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity;GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity;GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity GO:0010564//regulation of cell cycle process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0008283//cell proliferation;GO:0010564//regulation of cell cycle process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0008283//cell proliferation;GO:0010564//regulation of cell cycle process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0008283//cell proliferation;GO:0010564//regulation of cell cycle process;GO:0006464//cellular protein modification process;GO:0006796//phosphate-containing compound metabolic process;GO:0008283//cell proliferation "gi|148688225|gb|EDL20172.1|/0/cell division cycle 7 (S. cerevisiae), isoform CRA_b, partial [Mus musculus]" 18602 2640 0.176666667 0.183333333 0.053439259 Up 0.087912295 Padi4 "peptidyl arginine deiminase, type IV" K01481|1|0.0|1328|mmu:18602|protein-arginine deiminase [EC:3.5.3.15] GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding "GO:0018195//peptidyl-arginine modification;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" gi|156938252|ref|NP_035191.2|/0/protein-arginine deiminase type-4 [Mus musculus] 23859 5933 0.186666667 0.18 -0.05246742 Down 0.087912295 Dlg2 "discs, large homolog 2 (Drosophila)" K12075|1|0.0|880|hgl:101712252|discs large protein 2/3 GO:0044297//cell body;GO:0033267;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0044424 GO:0019902//phosphatase binding;GO:0046983//protein dimerization activity;GO:0019904//protein domain specific binding GO:0072657//protein localization to membrane;GO:0007600//sensory perception;GO:0007267//cell-cell signaling;GO:0010921//regulation of phosphatase activity gi|26333445|dbj|BAC30440.1|/0/unnamed protein product [Mus musculus] 16369 2337 0.4 0.386666667 -0.0489096 Down 0.087912295 Irs3 insulin receptor substrate 3 K17445|1|0.0|965|mmu:16369|insulin receptor substrate 3 GO:0016020//membrane;GO:0044444//cytoplasmic part;GO:0043227//membrane-bounded organelle GO:0005515//protein binding - gi|33468905|ref|NP_034701.1|/0/insulin receptor substrate 3 [Mus musculus] 109222 1411 0.276666667 0.266666667 -0.053111336 Down 0.087912295 Rarres1 retinoic acid receptor responder (tazarotene induced) 1 - - - - gi|26346258|dbj|BAC36780.1|/2.70326e-174/unnamed protein product [Mus musculus] 114714 2954 0.3 0.31 0.047305715 Up 0.087912295 Rad51c RAD51 paralog C K10870|1|0.0|654|mmu:114714|RAD51-like protein 2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0044444//cytoplasmic part "GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0016889//endodeoxyribonuclease activity, producing 3'-phosphomonoesters;GO:0032550;GO:0003676//nucleic acid binding;GO:0042623//ATPase activity, coupled;GO:0016889//endodeoxyribonuclease activity, producing 3'-phosphomonoesters" GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0007059//chromosome segregation;GO:0007143//female meiotic division;GO:0007127//meiosis I;GO:0048232//male gamete generation;GO:0006259//DNA metabolic process;GO:0033554//cellular response to stress;GO:0007059//chromosome segregation;GO:0007143//female meiotic division;GO:0007127//meiosis I;GO:0048232//male gamete generation gi|16716605|ref|NP_444499.1|/0/DNA repair protein RAD51 homolog 3 isoform 2 [Mus musculus] 26942 3270 0.27 0.263333333 -0.036069255 Down 0.087075482 Spag1 sperm associated antigen 1 K19870|1|0.0|1765|mmu:26942|sperm-associated antigen 1 GO:0044424 GO:0003824//catalytic activity;GO:0032550 GO:0009566//fertilization "gi|148676879|gb|EDL08826.1|/0/sperm associated antigen 1, isoform CRA_b, partial [Mus musculus]" 246102 7280 0.353333333 0.343333333 -0.041419927 Down 0.087075482 Rttn rotatin K16484|1|0.0|4081|mmu:246102|rotatin - - - gi|37704389|ref|NP_780751.2|/0/rotatin [Mus musculus] 54635 3512 0.463333333 0.45 -0.042125476 Down 0.087075482 Pdgfc "platelet-derived growth factor, C polypeptide" K05450|1|0.0|642|mmu:54635|platelet derived growth factor C/D GO:0043231//intracellular membrane-bounded organelle;GO:0044421 GO:0070851//growth factor receptor binding;GO:0042802//identical protein binding GO:0009653//anatomical structure morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0001932//regulation of protein phosphorylation;GO:0043200//response to amino acid;GO:0006260//DNA replication gi|10242385|ref|NP_064355.1|/0/platelet-derived growth factor C precursor [Mus musculus] 71912 1116 0.316666667 0.326666667 0.044854236 Up 0.087075482 Jsrp1 junctional sarcoplasmic reticulum protein 1 - GO:0005783//endoplasmic reticulum GO:0005488//binding GO:1901019//regulation of calcium ion transmembrane transporter activity gi|326807033|ref|NP_082277.2|/2.7388e-96/junctional sarcoplasmic reticulum protein 1 [Mus musculus] 100862015 1240 0.213333333 0.22 0.044394119 Up 0.087075482 Gm11236 predicted gene 11236 - - - - - 545370 18316 0.366666667 0.376666667 0.038819249 Up 0.087075482 Hmcn1 hemicentin 1 K17341|1|0.0|1.133e+04|mmu:545370|hemicentin - - - gi|154689979|ref|NP_001019891.2|/0/hemicentin-1 precursor [Mus musculus] 15401 1528 0.353333333 0.363333333 0.04026387 Up 0.087075482 Hoxa4 homeobox A4 K09304|1|5e-81|304|mmu:15401|homeobox protein HoxA/B/C/D4 GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0003002//regionalization;GO:0048562//embryonic organ morphogenesis;GO:0006351//transcription, DNA-templated" gi|46275810|ref|NP_032291.1|/4.3217e-80/homeobox protein Hox-A4 [Mus musculus] 23792 6271 0.353333333 0.343333333 -0.041419927 Down 0.087075482 Adam23 a disintegrin and metallopeptidase domain 23 K06837|1|0.0|1601|mmu:23792|disintegrin and metalloproteinase domain-containing protein 23 [EC:3.4.24.-] - - - - 243328 2942 0.483333333 0.47 -0.040357738 Down 0.087075482 Slc29a4 "solute carrier family 29 (nucleoside transporters), member 4" "K03323|1|0.0|995|mmu:243328|solute carrier family 29 (equilibrative nucleoside transporter), member 4" GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization gi|22122849|ref|NP_666369.1|/0/equilibrative nucleoside transporter 4 [Mus musculus] 381352 3990 0.466666667 0.453333333 -0.041820176 Down 0.087075482 Mamdc4 MAM domain containing 4 K18762|1|9e-87|325|ecb:100146768|zygote arrest protein 1 - - - - 404710 5676 0.476666667 0.463333333 -0.040930264 Down 0.087075482 Iqgap3 IQ motif containing GTPase activating protein 3 K05767|1|0.0|2908|mmu:404710|Ras GTPase-activating-like protein IQGAP2/3 - - - gi|118344446|ref|NP_001028656.1|/0/ras GTPase-activating-like protein IQGAP3 [Mus musculus] 73761 1010 0.263333333 0.256666667 -0.036994207 Down 0.087075482 4833415N18Rik RIKEN cDNA 4833415N18 gene - - - - - 353499 2346 0.376666667 0.386666667 0.037802033 Up 0.087075482 Tmc4 transmembrane channel-like gene family 4 K13516|1|1e-23|114|cge:100766440|lysophospholipid acyltransferase 7 [EC:2.3.1.-];K10877|2|6e-07|58.9|tsp:Tsp_10860|DNA repair and recombination protein RAD54B [EC:3.6.4.-] GO:0031224//intrinsic component of membrane - - gi|116063552|ref|NP_861541.2|/0/transmembrane channel-like protein 4 [Mus musculus] 319783 2973 0.366666667 0.356666667 -0.039892727 Down 0.087075482 A730056A06Rik RIKEN cDNA A730056A06 gene - - - - - 227659 1993 0.226666667 0.22 -0.043068722 Down 0.087075482 Slc2a6 "solute carrier family 2 (facilitated glucose transporter), member 6" "K08144|1|0.0|824|cge:100769228|MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 6" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0015149//hexose transmembrane transporter activity GO:0044765//single-organism transport;GO:0008645//hexose transport;GO:0044763 "gi|153945872|ref|NP_766247.2|/0/solute carrier family 2, facilitated glucose transporter member 6 isoform 1 [Mus musculus]" 100996933 4916 0.523333333 0.536666667 0.036296129 Up 0.087075482 Lincred1 long intergenic non-protein coding RNA of erythroid differentiation 1 - - - - - 228139 4190 0.27 0.263333333 -0.036069255 Down 0.087075482 P2rx3 "purinergic receptor P2X, ligand-gated ion channel, 3" K05217|1|0.0|812|mmu:228139|P2X purinoceptor 3 - - - - 100302498 128 0.53 0.516666667 -0.03675855 Down 0.087075482 Snora21 "small nucleolar RNA, H/ACA box 21" - - - - - 24050 4731 0.256666667 0.263333333 0.036994207 Up 0.087075482 3-Sep septin 3 K16938|1|0.0|703|cfa:481227|septin 3/9/12 GO:0032156//septin cytoskeleton;GO:0044444//cytoplasmic part;GO:0097060//synaptic membrane;GO:0042995//cell projection GO:0032550 GO:0044763 gi|4106549|gb|AAD02884.1|/0/neuronal-specific septin 3 [Mus musculus] 14676 1974 0.38 0.39 0.037474705 Up 0.087075482 Gna15 "guanine nucleotide binding protein, alpha 15" K04637|1|0.0|716|mmu:14676|guanine nucleotide-binding protein subunit alpha-15 - - - gi|6754010|ref|NP_034434.1|/0/guanine nucleotide-binding protein subunit alpha-15 [Mus musculus] 12265 5167 0.213333333 0.22 0.044394119 Up 0.087075482 Ciita class II transactivator "K08060|1|0.0|2004|mmu:12265|class II, major histocompatibility complex, transactivator" GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body GO:0032550;GO:0000975//regulatory region DNA binding;GO:0008134//transcription factor binding;GO:0032550;GO:0000975//regulatory region DNA binding;GO:0008134//transcription factor binding;GO:0032550;GO:0000975//regulatory region DNA binding;GO:0008134//transcription factor binding;GO:0032550;GO:0000975//regulatory region DNA binding;GO:0008134//transcription factor binding;GO:0032550;GO:0000975//regulatory region DNA binding;GO:0008134//transcription factor binding GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0009636//response to toxic substance;GO:0034341//response to interferon-gamma;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0009636//response to toxic substance;GO:0034341//response to interferon-gamma;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0009636//response to toxic substance;GO:0034341//response to interferon-gamma;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0009636//response to toxic substance;GO:0034341//response to interferon-gamma;GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0009636//response to toxic substance;GO:0034341//response to interferon-gamma gi|344217728|ref|NP_001230690.1|/0/MHC class II transactivator isoform 3 [Mus musculus] 19650 4462.01 0.503333333 0.516666667 0.037719666 Up 0.087075482 Rbl1 retinoblastoma-like 1 (p107) K04681|1|0.0|2055|mmu:19650|retinoblastoma-like protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005515//protein binding "GO:0019216//regulation of lipid metabolic process;GO:0007049//cell cycle;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" gi|213417872|ref|NP_001132988.1|/0/retinoblastoma-like protein 1 isoform 2 [Mus musculus] 100038363 2796 0.523333333 0.536666667 0.036296129 Up 0.087075482 F630028O10Rik RIKEN cDNA F630028O10 gene - - - - gi|148682272|gb|EDL14219.1|/2.70653e-31/mCG147482 [Mus musculus] 22003 1211.73 9588.886667 9603.083333 0.002134379 Up 0.087037873 Tpm1 "tropomyosin 1, alpha" K10373|1|1e-112|409|pale:102887701|tropomyosin 1 GO:0043005//neuron projection;GO:0005865//striated muscle thin filament;GO:0005884//actin filament;GO:0032432//actin filament bundle;GO:0032155;GO:0001726//ruffle;GO:0043005//neuron projection;GO:0005865//striated muscle thin filament;GO:0005884//actin filament;GO:0032432//actin filament bundle;GO:0032155;GO:0001726//ruffle;GO:0043005//neuron projection;GO:0005865//striated muscle thin filament;GO:0005884//actin filament;GO:0032432//actin filament bundle;GO:0032155;GO:0001726//ruffle;GO:0043005//neuron projection;GO:0005865//striated muscle thin filament;GO:0005884//actin filament;GO:0032432//actin filament bundle;GO:0032155;GO:0001726//ruffle;GO:0043005//neuron projection;GO:0005865//striated muscle thin filament;GO:0005884//actin filament;GO:0032432//actin filament bundle;GO:0032155;GO:0001726//ruffle;GO:0043005//neuron projection;GO:0005865//striated muscle thin filament;GO:0005884//actin filament;GO:0032432//actin filament bundle;GO:0032155;GO:0001726//ruffle;GO:0043005//neuron projection;GO:0005865//striated muscle thin filament;GO:0005884//actin filament;GO:0032432//actin filament bundle;GO:0032155;GO:0001726//ruffle;GO:0043005//neuron projection;GO:0005865//striated muscle thin filament;GO:0005884//actin filament;GO:0032432//actin filament bundle;GO:0032155;GO:0001726//ruffle;GO:0043005//neuron projection;GO:0005865//striated muscle thin filament;GO:0005884//actin filament;GO:0032432//actin filament bundle;GO:0032155;GO:0001726//ruffle;GO:0005865//striated muscle thin filament;GO:0005884//actin filament;GO:0032432//actin filament bundle;GO:0001726//ruffle GO:0005198//structural molecule activity;GO:0042802//identical protein binding;GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0042802//identical protein binding;GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0042802//identical protein binding;GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0042802//identical protein binding;GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0042802//identical protein binding;GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0042802//identical protein binding;GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0042802//identical protein binding;GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0042802//identical protein binding;GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0042802//identical protein binding;GO:0003779//actin binding;GO:0005198//structural molecule activity;GO:0042802//identical protein binding;GO:0003779//actin binding GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0030239//myofibril assembly;GO:0043462//regulation of ATPase activity;GO:0016477//cell migration;GO:0006941//striated muscle contraction;GO:0000302//response to reactive oxygen species;GO:0032233//positive regulation of actin filament bundle assembly;GO:0007155//cell adhesion;GO:0030835//negative regulation of actin filament depolymerization;GO:0030030//cell projection organization;GO:0003208//cardiac ventricle morphogenesis;GO:0009611//response to wounding;GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0030239//myofibril assembly;GO:0043009//chordate embryonic development;GO:0043462//regulation of ATPase activity;GO:0016477//cell migration;GO:0006941//striated muscle contraction;GO:0000302//response to reactive oxygen species;GO:0032233//positive regulation of actin filament bundle assembly;GO:0007155//cell adhesion;GO:0030835//negative regulation of actin filament depolymerization;GO:0030030//cell projection organization;GO:0003208//cardiac ventricle morphogenesis;GO:0009611//response to wounding;GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0030239//myofibril assembly;GO:0043009//chordate embryonic development;GO:0043462//regulation of ATPase activity;GO:0016477//cell migration;GO:0006941//striated muscle contraction;GO:0000302//response to reactive oxygen species;GO:0032233//positive regulation of actin filament bundle assembly;GO:0007155//cell adhesion;GO:0030835//negative regulation of actin filament depolymerization;GO:0030030//cell projection organization;GO:0003208//cardiac ventricle morphogenesis;GO:0009611//response to wounding;GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0030239//myofibril assembly;GO:0043009//chordate embryonic development;GO:0043462//regulation of ATPase activity;GO:0016477//cell migration;GO:0006941//striated muscle contraction;GO:0000302//response to reactive oxygen species;GO:0032233//positive regulation of actin filament bundle assembly;GO:0007155//cell adhesion;GO:0030835//negative regulation of actin filament depolymerization;GO:0030030//cell projection organization;GO:0003208//cardiac ventricle morphogenesis;GO:0009611//response to wounding;GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0030239//myofibril assembly;GO:0043009//chordate embryonic development;GO:0043462//regulation of ATPase activity;GO:0016477//cell migration;GO:0006941//striated muscle contraction;GO:0000302//response to reactive oxygen species;GO:0032233//positive regulation of actin filament bundle assembly;GO:0007155//cell adhesion;GO:0030835//negative regulation of actin filament depolymerization;GO:0030030//cell projection organization;GO:0003208//cardiac ventricle morphogenesis;GO:0009611//response to wounding;GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0030239//myofibril assembly;GO:0043009//chordate embryonic development;GO:0043462//regulation of ATPase activity;GO:0016477//cell migration;GO:0006941//striated muscle contraction;GO:0000302//response to reactive oxygen species;GO:0032233//positive regulation of actin filament bundle assembly;GO:0007155//cell adhesion;GO:0030835//negative regulation of actin filament depolymerization;GO:0030030//cell projection organization;GO:0003208//cardiac ventricle morphogenesis;GO:0009611//response to wounding;GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0030239//myofibril assembly;GO:0043462//regulation of ATPase activity;GO:0016477//cell migration;GO:0006941//striated muscle contraction;GO:0000302//response to reactive oxygen species;GO:0032233//positive regulation of actin filament bundle assembly;GO:0007155//cell adhesion;GO:0030835//negative regulation of actin filament depolymerization;GO:0030030//cell projection organization;GO:0003208//cardiac ventricle morphogenesis;GO:0009611//response to wounding;GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0030239//myofibril assembly;GO:0043462//regulation of ATPase activity;GO:0016477//cell migration;GO:0006941//striated muscle contraction;GO:0000302//response to reactive oxygen species;GO:0032233//positive regulation of actin filament bundle assembly;GO:0007155//cell adhesion;GO:0030835//negative regulation of actin filament depolymerization;GO:0030030//cell projection organization;GO:0003208//cardiac ventricle morphogenesis;GO:0009611//response to wounding;GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0030239//myofibril assembly;GO:0043009//chordate embryonic development;GO:0043462//regulation of ATPase activity;GO:0016477//cell migration;GO:0006941//striated muscle contraction;GO:0000302//response to reactive oxygen species;GO:0032233//positive regulation of actin filament bundle assembly;GO:0007155//cell adhesion;GO:0030835//negative regulation of actin filament depolymerization;GO:0030030//cell projection organization;GO:0003208//cardiac ventricle morphogenesis;GO:0009611//response to wounding;GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0030239//myofibril assembly;GO:0009790//embryo development;GO:0043462//regulation of ATPase activity;GO:0016477//cell migration;GO:0006941//striated muscle contraction;GO:0000302//response to reactive oxygen species;GO:0032233//positive regulation of actin filament bundle assembly;GO:0007155//cell adhesion;GO:0030835//negative regulation of actin filament depolymerization;GO:0030030//cell projection organization;GO:0003208//cardiac ventricle morphogenesis;GO:0009611//response to wounding gi|256000796|ref|NP_001157728.1|/3.34961e-104/tropomyosin alpha-1 chain isoform Tpm1.12br [Mus musculus] 21954 854 5845.683333 5848.48 0.000690043 Up 0.087009666 Tnni3 "troponin I, cardiac 3" "K12044|1|5e-88|326|mmu:21954|troponin I, cardiac muscle" GO:0005865//striated muscle thin filament GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding;GO:0019900//kinase binding;GO:0005246//calcium channel regulator activity GO:0006941//striated muscle contraction;GO:0043462//regulation of ATPase activity;GO:0006937//regulation of muscle contraction;GO:0003208//cardiac ventricle morphogenesis;GO:0001976//neurological system process involved in regulation of systemic arterial blood pressure;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0003015//heart process;GO:0006875//cellular metal ion homeostasis "gi|6678393|ref|NP_033432.1|/4.3049e-87/troponin I, cardiac muscle [Mus musculus]" 66218 651 821.5433333 824.22 0.004692798 Up 0.087009666 Ndufb9 "NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9" K03965|1|3e-109|396|mmu:66218|NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9 GO:0005746//mitochondrial respiratory chain - GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy gi|29789148|ref|NP_075661.1|/1.90192e-108/NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 [Mus musculus] 68337 1454 883.4933333 881.2433333 -0.00367881 Down 0.087000263 Crip2 cysteine rich protein 2 K09377|1|8e-33|144|nve:NEMVE_v1g52979|cysteine and glycine-rich protein GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding GO:0008283//cell proliferation;GO:0048534//hematopoietic or lymphoid organ development gi|589950860|ref|XP_006988081.1|/1.9181e-122/PREDICTED: cysteine-rich protein 2 [Peromyscus maniculatus bairdii] 78560 5520 3.96 3.943333333 -0.006084762 Down 0.086962654 Adgra2 adhesion G protein-coupled receptor A2 K08461|1|0.0|2430|mmu:78560|G protein-coupled receptor 124 GO:0031224//intrinsic component of membrane;GO:0044464 GO:0004888//transmembrane signaling receptor activity GO:0001525//angiogenesis;GO:0009968//negative regulation of signal transduction;GO:0006935//chemotaxis;GO:0060284//regulation of cell development;GO:0007399//nervous system development;GO:0010594//regulation of endothelial cell migration;GO:0007186//G-protein coupled receptor signaling pathway gi|300934759|ref|NP_473385.2|/0/G-protein coupled receptor 124 precursor [Mus musculus] 100038595 2322 2.213333333 2.23 0.010822969 Up 0.086962654 Gm16287 predicted gene 16287 - - - - gi|74187885|dbj|BAE24563.1|/6.2886e-55/unnamed protein product [Mus musculus] 320737 551 4.72 4.7 -0.006126103 Down 0.086962654 4732416N19Rik RIKEN cDNA 4732416N19 gene - - - - - 238831 2367 1.64 1.623333333 -0.014736543 Down 0.086962654 Ppwd1 peptidylprolyl isomerase domain and WD repeat containing 1 K12736|1|0.0|1300|mmu:238831|peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC:5.2.1.8] GO:0005681//spliceosomal complex GO:0016859//cis-trans isomerase activity GO:0000377;GO:0018208//peptidyl-proline modification "gi|148686551|gb|EDL18498.1|/0/peptidylprolyl isomerase domain and WD repeat containing 1, partial [Mus musculus]" 13809 4208 2.676666667 2.66 -0.009011241 Down 0.086962654 Enpep glutamyl aminopeptidase K11141|1|0.0|1854|mmu:13809|glutamyl aminopeptidase [EC:3.4.11.7] GO:0031224//intrinsic component of membrane;GO:0031988//membrane-bounded vesicle;GO:0044459;GO:0009986//cell surface;GO:0042995//cell projection;GO:0012505//endomembrane system GO:0046914//transition metal ion binding;GO:0004177//aminopeptidase activity;GO:0033218//amide binding GO:0001990//regulation of systemic arterial blood pressure by hormone;GO:0048870//cell motility;GO:0019538//protein metabolic process;GO:0044237//cellular metabolic process gi|6679653|ref|NP_031960.1|/0/glutamyl aminopeptidase [Mus musculus] 399609 3439.93 3.393333333 3.376666667 -0.007103387 Down 0.086962654 C130046K22Rik RIKEN cDNA C130046K22 gene - - - - gi|148677539|gb|EDL09486.1|/1.77333e-19/mCG147332 [Mus musculus] 15476 1685 3.436666667 3.413333333 -0.009828617 Down 0.086962654 Hs3st1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 K01024|1|9e-175|615|mmu:15476|[heparan sulfate]-glucosamine 3-sulfotransferase 1 [EC:2.8.2.23] GO:0044431//Golgi apparatus part GO:0034483//heparan sulfate sulfotransferase activity - gi|6754246|ref|NP_034604.1|/7.67424e-174/heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor [Mus musculus] 14256 1075 3.626666667 3.61 -0.006645314 Down 0.086962654 Flt3l FMS-like tyrosine kinase 3 ligand K05454|1|1e-103|307|mmu:14256|fms-related tyrosine kinase 3 ligand GO:0031224//intrinsic component of membrane;GO:0009897//external side of plasma membrane;GO:0044421;GO:0031224//intrinsic component of membrane;GO:0009897//external side of plasma membrane;GO:0044421 "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0042802//identical protein binding;GO:0005102//receptor binding" GO:0001779//natural killer cell differentiation;GO:0006796//phosphate-containing compound metabolic process;GO:0008283//cell proliferation;GO:0001779//natural killer cell differentiation;GO:0006796//phosphate-containing compound metabolic process;GO:0008283//cell proliferation gi|568947293|ref|XP_006540672.1|/1.71634e-124/PREDICTED: fms-related tyrosine kinase 3 ligand isoform X2 [Mus musculus] 142980 4327 2.263333333 2.286666667 0.014797002 Up 0.086962654 Tlr3 toll-like receptor 3 K05401|1|0.0|1692|mmu:142980|toll-like receptor 3 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0038023//signaling receptor activity;GO:0003723//RNA binding GO:0006954//inflammatory response;GO:0042095//interferon-gamma biosynthetic process;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0035456//response to interferon-beta;GO:0006915//apoptotic process;GO:0032481//positive regulation of type I interferon production;GO:0008406//gonad development;GO:0009612//response to mechanical stimulus;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0034341//response to interferon-gamma;GO:0043330//response to exogenous dsRNA;GO:0007254//JNK cascade;GO:0052166;GO:0002252;GO:0001774//microglial cell activation;GO:0006366//transcription from RNA polymerase II promoter;GO:0002224//toll-like receptor signaling pathway;GO:0042493//response to drug;GO:0006468//protein phosphorylation;GO:0042033//chemokine biosynthetic process;GO:0042345//regulation of NF-kappaB import into nucleus "gi|148703601|gb|EDL35548.1|/0/toll-like receptor 3, isoform CRA_a, partial [Mus musculus]" 216795 3318 2.103333333 2.083333333 -0.013783815 Down 0.086962654 Wnt9a "wingless-type MMTV integration site family, member 9A" "K01064|1|0.0|658|mmu:216795|wingless-type MMTV integration site family, member 9" - - - gi|21314846|ref|NP_647459.1|/0/protein Wnt-9a precursor [Mus musculus] 77462 1342.27 3.963333333 3.98 0.006054122 Up 0.086962654 Tmem116 transmembrane protein 116 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|239052203|ref|NP_001155099.1|/0/transmembrane protein 116 isoform 1 [Mus musculus] 213499 5943 3.853333333 3.873333333 0.007468671 Up 0.086962654 Fbxo42 F-box protein 42 K10317|1|0.0|1348|mmu:213499|F-box protein 42 - - - gi|40254217|ref|NP_766106.2|/0/F-box only protein 42 [Mus musculus] 13836 3948 4.613333333 4.596666667 -0.005221486 Down 0.086962654 Epha2 Eph receptor A2 K05103|1|0.0|1886|mmu:13836|Eph receptor A2 [EC:2.7.10.1] - - - - 68691 4628 3.063333333 3.04 -0.011031037 Down 0.086962654 Kansl1l KAT8 regulatory NSL complex subunit 1-like K18400|1|1e-60|238|mdo:103092583|KAT8 regulatory NSL complex subunit 1 - - - gi|170172570|ref|NP_001116210.1|/0/KAT8 regulatory NSL complex subunit 1-like protein isoform 1 [Mus musculus] 14679 3294 4.163333333 4.183333333 0.006913887 Up 0.086962654 Gnai3 "guanine nucleotide binding protein (G protein), alpha inhibiting 3" K04630|1|0.0|673|mmu:14679|guanine nucleotide-binding protein G(i) subunit alpha - - - "gi|148670001|gb|EDL01948.1|/0/guanine nucleotide binding protein, alpha inhibiting 3, isoform CRA_a, partial [Mus musculus]" 68018 5308.02 4.883333333 4.906666667 0.006877007 Up 0.086962654 Col4a3bp "collagen, type IV, alpha 3 (Goodpasture antigen) binding protein" K08283|1|0.0|1168|fca:101099355|collagen type IV alpha-3-binding protein GO:0031981//nuclear lumen;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0031090//organelle membrane;GO:0044444//cytoplasmic part GO:0016301//kinase activity;GO:0046624//sphingolipid transporter activity;GO:0046625//sphingolipid binding;GO:1901981//phosphatidylinositol phosphate binding;GO:0016301//kinase activity;GO:0046624//sphingolipid transporter activity;GO:0046625//sphingolipid binding;GO:1901981//phosphatidylinositol phosphate binding GO:0003012//muscle system process;GO:0032365//intracellular lipid transport;GO:0006665//sphingolipid metabolic process;GO:0048878//chemical homeostasis;GO:0006796//phosphate-containing compound metabolic process;GO:0043009//chordate embryonic development;GO:0007154//cell communication;GO:0009887//organ morphogenesis;GO:0006464//cellular protein modification process;GO:0002376//immune system process;GO:0007005//mitochondrion organization;GO:0033554//cellular response to stress;GO:0003012//muscle system process;GO:0032365//intracellular lipid transport;GO:0006665//sphingolipid metabolic process;GO:0048878//chemical homeostasis;GO:0006796//phosphate-containing compound metabolic process;GO:0043009//chordate embryonic development;GO:0007154//cell communication;GO:0009887//organ morphogenesis;GO:0006464//cellular protein modification process;GO:0002376//immune system process;GO:0007005//mitochondrion organization;GO:0033554//cellular response to stress gi|586974999|ref|XP_006927856.1|/0/PREDICTED: collagen type IV alpha-3-binding protein isoform X1 [Felis catus] 67153 1457 3.78 3.803333333 0.008878151 Up 0.086962654 Rnaseh2b "ribonuclease H2, subunit B" K10744|1|8e-151|536|mmu:67153|ribonuclease H2 subunit B GO:0043234//protein complex;GO:0031981//nuclear lumen - GO:0016070//RNA metabolic process "gi|312208160|pdb|3P5J|B/6.34505e-150/Chain B, The Structure Of The Human Rnase H2 Complex Defines Key Interaction Interfaces Relevant To Enzyme Function And Human Disease" 77809 1756 3.976666667 4 0.008440363 Up 0.086962654 Lrrc42 leucine rich repeat containing 42 - - - - gi|33859742|ref|NP_084261.1|/0/leucine-rich repeat-containing protein 42 [Mus musculus] 66799 3075.12 4.513333333 4.536666667 0.007439328 Up 0.086962654 Ube2w ubiquitin-conjugating enzyme E2W (putative) K10688|1|9e-66|181|mmu:66799|ubiquitin-conjugating enzyme E2 W [EC:2.3.2.25] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0032550;GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0032550;GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0032550;GO:0044389//ubiquitin-like protein ligase binding;GO:0019787//ubiquitin-like protein transferase activity GO:0035967//cellular response to topologically incorrect protein;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006259//DNA metabolic process;GO:0000209//protein polyubiquitination;GO:0035967//cellular response to topologically incorrect protein;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006259//DNA metabolic process;GO:0000209//protein polyubiquitination;GO:0035967//cellular response to topologically incorrect protein;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006259//DNA metabolic process;GO:0000209//protein polyubiquitination;GO:0035967//cellular response to topologically incorrect protein;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006259//DNA metabolic process;GO:0000209//protein polyubiquitination gi|401891882|ref|NP_080049.2|/1.19434e-91/ubiquitin-conjugating enzyme E2 W isoform 1 [Mus musculus] 329659 1541 4.49 4.466666667 -0.00751685 Down 0.086962654 E130311K13Rik RIKEN cDNA E130311K13 gene K02970|1|1e-14|84.0|tsp:Tsp_11893|small subunit ribosomal protein S21;K17081|2|3e-12|75.9|loa:LOAG_08798|prohibitin 2 GO:0031224//intrinsic component of membrane GO:0097159//organic cyclic compound binding - gi|29244450|ref|NP_808524.1|/4.70931e-167/protein C3orf33 homolog [Mus musculus] 237221 1919.56 2.66 2.683333333 0.012600037 Up 0.086962654 Gemin8 gem (nuclear organelle) associated protein 8 K13136|1|3e-117|424|mmu:237221|gem associated protein 8 GO:0043234//protein complex;GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0030529//intracellular ribonucleoprotein complex;GO:0031981//nuclear lumen - GO:0006396//RNA processing;GO:0006396//RNA processing;GO:0006396//RNA processing "gi|148686487|gb|EDL18434.1|/2.01337e-124/mCG49489, partial [Mus musculus]" 27078 816 3.49 3.47 -0.008291374 Down 0.086962654 B9d1 B9 protein domain 1 K16744|1|1e-117|424|mmu:27078|B9 domain-containing protein 1 GO:0005815//microtubule organizing center;GO:0035869//ciliary transition zone;GO:0005930//axoneme GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity GO:0001654//eye development;GO:0048858//cell projection morphogenesis;GO:0010927;GO:0007507//heart development;GO:0007166//cell surface receptor signaling pathway;GO:0030154//cell differentiation;GO:0008104//protein localization;GO:0030326//embryonic limb morphogenesis gi|7305039|ref|NP_038745.1|/1.06756e-116/B9 domain-containing protein 1 precursor [Mus musculus] 243813 1690 2.346666667 2.366666667 0.012243596 Up 0.086962654 Leng9 leukocyte receptor cluster (LRC) member 9 K19663|1|2e-27|126|cjo:107307120|classical protein kinase C gamma type [EC:2.7.11.13];K10669|2|2e-23|112|cin:100175594|2'-phosphotransferase [EC:2.7.1.160] GO:0044464 GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0044260 gi|30425300|ref|NP_780738.1|/0/leukocyte receptor cluster member 9 [Mus musculus] 210135 3924 5.37 5.346666667 -0.006282352 Down 0.086962654 Zfp180 zinc finger protein 180 K09228|1|0.0|1220|mmu:210135|KRAB domain-containing zinc finger protein GO:0044464;GO:0044464;GO:0044464;GO:0044464;GO:0044464;GO:0044464 GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - "gi|148692409|gb|EDL24356.1|/0/zinc finger protein 180, isoform CRA_a, partial [Mus musculus]" 12366 3545 2.536666667 2.556666667 0.011330124 Up 0.086962654 Casp2 caspase 2 K02186|1|0.0|900|mmu:12366|caspase 2 [EC:3.4.22.55] GO:0043231//intracellular membrane-bounded organelle GO:0004175//endopeptidase activity;GO:0005515//protein binding "GO:0012502//induction of programmed cell death;GO:0007417//central nervous system development;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0043065//positive regulation of apoptotic process;GO:0051604//protein maturation;GO:0044767//single-organism developmental process;GO:0009612//response to mechanical stimulus" gi|6680848|ref|NP_031636.1|/0/caspase-2 precursor [Mus musculus] 217030 7112 5.466666667 5.486666667 0.005268521 Up 0.086962654 Synrg "synergin, gamma" K20045|1|7e-07|60.5|mze:101467790|intersectin;K12472|2|5e-06|57.8|aag:AaeL_AAEL007950|epidermal growth factor receptor substrate 15 GO:0012510//trans-Golgi network transport vesicle membrane GO:0046872//metal ion binding GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport gi|34996507|ref|NP_919322.1|/0/synergin gamma [Mus musculus] 329679 7095 2.503333333 2.523333333 0.011480392 Up 0.086962654 Fnip2 folliculin interacting protein 2 K20401|1|0.0|2003|mmu:329679|folliculin-interacting protein 2 GO:0044424 - GO:0001934//positive regulation of protein phosphorylation;GO:0006974//cellular response to DNA damage stimulus gi|244790458|ref|NP_001156471.1|/0/folliculin-interacting protein 2 [Mus musculus] 242747 4283 1.883333333 1.866666667 -0.01282404 Down 0.086962654 Zfp933 zinc finger protein 933 K09228|1|0.0|1028|mmu:242747|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|38348488|ref|NP_941021.1|/0/uncharacterized protein LOC242747 [Mus musculus] 109685 1830 2.64 2.656666667 0.009079294 Up 0.086962654 Hyal3 hyaluronoglucosaminidase 3 K01197|1|0.0|884|mmu:109685|hyaluronoglucosaminidase [EC:3.2.1.35] - - - gi|254939507|ref|NP_821139.2|/0/hyaluronidase-3 precursor [Mus musculus] 216856 5034 4.563333333 4.58 0.005259558 Up 0.086962654 Nlgn2 neuroligin 2 K07378|1|0.0|1352|mmu:216856|neuroligin - - - gi|50510903|dbj|BAD32437.1|/0/mKIAA1366 protein [Mus musculus] 319817 8962 2.816666667 2.8 -0.008562014 Down 0.086962654 Rc3h2 ring finger and CCCH-type zinc finger domains 2 K15690|1|0.0|2105|mmu:319817|RING finger and CCCH-type zinc finger domain-containing protein - - - - 232334 1327 4.486666667 4.466666667 -0.006445409 Down 0.086962654 Vgll4 vestigial like family member 4 - GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated" gi|29244116|ref|NP_808351.1|/3.05855e-148/transcription cofactor vestigial-like protein 4 [Mus musculus] 100504467 1456.65 3.016666667 3.04 0.011116032 Up 0.086962654 Gm16596 "predicted gene, 16596" K18595|1|7e-20|101|mmu:68519|echinoderm microtubule-associated protein-like 1/2 - - - - 24082 1267 4.013333333 4.033333333 0.007171655 Up 0.086962654 Map2k3os "mitogen-activated protein kinase kinase 3, opposite strand" - - - - - 269113 2332 4.383333333 4.366666667 -0.005495988 Down 0.086962654 Nup54 nucleoporin 54 K14308|1|0.0|791|mmu:269113|nuclear pore complex protein Nup54 GO:0005635//nuclear envelope GO:0005488//binding GO:0050658//RNA transport;GO:0051169//nuclear transport;GO:0006886//intracellular protein transport gi|39930543|ref|NP_899248.1|/0/nuclear pore complex protein Nup54 [Mus musculus] 272428 2505 3.716666667 3.7 -0.006484034 Down 0.086962654 Acsm5 acyl-CoA synthetase medium-chain family member 5 K01896|1|0.0|1177|mmu:272428|medium-chain acyl-CoA synthetase [EC:6.2.1.2] GO:0044429 GO:0043169//cation binding;GO:0016878//acid-thiol ligase activity;GO:0032550 GO:0032787//monocarboxylic acid metabolic process;GO:0044238//primary metabolic process "gi|148685218|gb|EDL17165.1|/0/mCG5785, isoform CRA_b [Mus musculus]" 18516 2775.75 4.776666667 4.793333333 0.005025066 Up 0.086962654 Pbx3 pre B cell leukemia homeobox 3 K15610|1|0.0|755|rno:311876|pre-B-cell leukemia transcription factor 3 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0021510//spinal cord development;GO:0007626//locomotory behavior;GO:0007386//compartment pattern specification;GO:0006351//transcription, DNA-templated;GO:0050877//neurological system process;GO:0030182//neuron differentiation;GO:0021510//spinal cord development;GO:0007626//locomotory behavior;GO:0007386//compartment pattern specification;GO:0006351//transcription, DNA-templated;GO:0050877//neurological system process;GO:0030182//neuron differentiation" gi|114053107|ref|NP_001039918.1|/7.95325e-169/pre-B-cell leukemia transcription factor 3 [Bos taurus] 70779 2182 3.636666667 3.616666667 -0.007956059 Down 0.086962654 Prdm5 PR domain containing 5 K09228|1|1e-98|363|gja:107115679|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0044212//transcription regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0008134//transcription factor binding "GO:0034968//histone lysine methylation;GO:0006476//protein deacetylation;GO:0007049//cell cycle;GO:0006351//transcription, DNA-templated" gi|124286828|ref|NP_081823.2|/0/PR domain zinc finger protein 5 [Mus musculus] 17475 7443.05 5.193333333 5.17 -0.006496547 Down 0.086962654 Mpdz multiple PDZ domain protein K06095|1|0.0|3616|mmu:17475|multiple PDZ domain protein - - - - 57773 3906 1.996666667 1.976666667 -0.014523898 Down 0.086962654 Wdr4 WD repeat domain 4 K15443|1|0.0|886|mmu:57773|tRNA (guanine-N(7)-)-methyltransferase subunit TRM82 GO:0031981//nuclear lumen - GO:0001510//RNA methylation;GO:0008033//tRNA processing gi|255308863|ref|NP_067297.2|/0/tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 [Mus musculus] 17252 1574 2.336666667 2.356666667 0.012295771 Up 0.086962654 Rdh11 retinol dehydrogenase 11 K11152|1|2e-161|571|mmu:17252|retinol dehydrogenase 11 [EC:1.1.1.300] GO:0031224//intrinsic component of membrane;GO:0001750//photoreceptor outer segment GO:0036094//small molecule binding;GO:0008106//alcohol dehydrogenase (NADP+) activity GO:0016056//rhodopsin mediated signaling pathway;GO:0001523//retinoid metabolic process gi|6630624|dbj|BAA88521.1|/6.42219e-171/M42C60 [Mus musculus] 71148 4631 4.83 4.81 -0.005986295 Down 0.086962654 Mier1 MEIR1 treanscription regulator K11660|1|1e-09|69.3|ola:101156685|metastasis-associated protein MTA GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0005488//binding;GO:0060089;GO:0005488//binding;GO:0060089;GO:0005488//binding;GO:0060089;GO:0005488//binding;GO:0060089;GO:0003676//nucleic acid binding;GO:0060089 GO:0006342//chromatin silencing;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006342//chromatin silencing;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006342//chromatin silencing;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006342//chromatin silencing;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006342//chromatin silencing;GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|568929753|ref|XP_006503462.1|/0/PREDICTED: mesoderm induction early response protein 1 isoform X3 [Mus musculus] 50877 3341 2.306666667 2.283333333 -0.01466805 Down 0.086962654 Neu3 neuraminidase 3 K12357|1|0.0|885|mmu:50877|sialidase-2/3/4 [EC:3.2.1.18] GO:0016020//membrane GO:0004308//exo-alpha-sialidase activity GO:0044238//primary metabolic process gi|7710068|ref|NP_057929.1|/0/sialidase-3 [Mus musculus] 20683 7818 4.143333333 4.166666667 0.008101798 Up 0.086962654 Sp1 trans-acting transcription factor 1 K04684|1|0.0|1107|mmu:20683|transcription factor Sp1 GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0043566//structure-specific DNA binding;GO:0019899//enzyme binding" GO:0001501//skeletal system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007565//female pregnancy;GO:0030323//respiratory tube development;GO:0030218//erythrocyte differentiation;GO:0031076//embryonic camera-type eye development;GO:0001825//blastocyst formation;GO:0043921 gi|119226255|ref|NP_038700.2|/0/transcription factor Sp1 [Mus musculus] 353170 3814.19 2.103333333 2.123333333 0.013653367 Up 0.086962654 Txlng taxilin gamma K06106|1|3e-09|67.0|smm:Smp_164620|cortactin GO:0044444//cytoplasmic part;GO:0005635//nuclear envelope GO:0000149//SNARE binding;GO:0046983//protein dimerization activity "GO:0051726//regulation of cell cycle;GO:0030278//regulation of ossification;GO:0006351//transcription, DNA-templated" gi|595763530|ref|NP_001277706.1|/1.16175e-100/gamma-taxilin isoform 3 [Mus musculus] 19212 3706 2.66 2.676666667 0.009011241 Up 0.086962654 Pter phosphotriesterase related K07048|1|0.0|713|mmu:19212|phosphotriesterase-related protein - GO:0016787//hydrolase activity;GO:0046914//transition metal ion binding;GO:0016787//hydrolase activity;GO:0046914//transition metal ion binding;GO:0016787//hydrolase activity;GO:0046914//transition metal ion binding GO:0008152//metabolic process;GO:0008152//metabolic process;GO:0008152//metabolic process gi|767806534|ref|NP_001292366.1|/0/phosphotriesterase-related protein isoform 1 [Mus musculus] 11951 803.92 1257.013333 1257.933333 0.001055513 Up 0.086915642 Atp5g1 "ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)" K02128|1|9e-55|215|mmu:11951|F-type H+-transporting ATPase subunit c "GO:0031224//intrinsic component of membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0005743//mitochondrial inner membrane;GO:0031224//intrinsic component of membrane;GO:0033177//proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0005743//mitochondrial inner membrane" GO:0005488//binding;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0005488//binding;GO:0015077//monovalent inorganic cation transmembrane transporter activity "GO:0097305//response to alcohol;GO:0006754//ATP biosynthetic process;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0097305//response to alcohol;GO:0006754//ATP biosynthetic process;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient" "gi|31982497|ref|NP_031532.2|/7.3033e-54/ATP synthase F(0) complex subunit C1, mitochondrial [Mus musculus]" 56376 2128.93 280.9266667 279.9733333 -0.004904156 Down 0.086915642 Pdlim5 PDZ and LIM domain 5 K19867|1|3e-88|330|lcm:102345562|LIM domain-binding protein 3 GO:0005856//cytoskeleton;GO:0031674//I band;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0031674//I band;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0031674//I band;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0005856//cytoskeleton;GO:0031674//I band;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0031674//I band;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0031674//I band;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0031674//I band;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0031674//I band;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0031674//I band;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane GO:0008092//cytoskeletal protein binding;GO:0032947//protein complex scaffold;GO:0046914//transition metal ion binding;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0046914//transition metal ion binding;GO:0019901//protein kinase binding GO:0007416//synapse assembly;GO:0048814//regulation of dendrite morphogenesis;GO:0007416//synapse assembly;GO:0048814//regulation of dendrite morphogenesis;GO:0007416//synapse assembly;GO:0048814//regulation of dendrite morphogenesis;GO:0007416//synapse assembly;GO:0048814//regulation of dendrite morphogenesis;GO:0007416//synapse assembly;GO:0048814//regulation of dendrite morphogenesis;GO:0007416//synapse assembly;GO:0048814//regulation of dendrite morphogenesis;GO:0007416//synapse assembly;GO:0048814//regulation of dendrite morphogenesis;GO:0007416//synapse assembly;GO:0048814//regulation of dendrite morphogenesis;GO:0007416//synapse assembly;GO:0048814//regulation of dendrite morphogenesis gi|300069043|ref|NP_001177786.1|/5.29311e-124/PDZ and LIM domain protein 5 isoform ENH3a [Mus musculus] 66046 999 360.76 359.87 -0.003563546 Down 0.086906239 Ndufb5 "NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5" K03961|1|4e-106|386|mmu:66046|NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5 - - - - 227197 2714.83 206.5733333 207.23 0.004578844 Up 0.086821618 Ndufs1 NADH dehydrogenase (ubiquinone) Fe-S protein 1 K03934|1|0.0|1447|mmu:227197|NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3] - - - "gi|229892316|ref|NP_663493.2|/0/NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial precursor [Mus musculus]" 26549 1316 168.3666667 168.8866667 0.004448893 Up 0.086784008 Itgb1bp2 integrin beta 1 binding protein 2 K16735|1|0.0|671|mmu:26549|integrin beta-1-binding protein 2 GO:0031674//I band GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding GO:0007166//cell surface receptor signaling pathway gi|7305191|ref|NP_038740.1|/0/integrin beta-1-binding protein 2 [Mus musculus] 63954 595 152.5133333 153.0066667 0.00465914 Up 0.086774606 Rbp7 "retinol binding protein 7, cellular" K06210|1|6e-59|228|gja:107107374|nicotinamide mononucleotide adenylyltransferase [EC:2.7.7.1 2.7.7.18];K14622|2|2e-48|193|gfr:102039428|retinol binding protein 2 GO:0044424 GO:0005501//retinoid binding GO:0051234//establishment of localization gi|11968156|ref|NP_071303.1|/1.88719e-74/retinoid-binding protein 7 [Mus musculus] 66270 2930.89 141.41 141.0733333 -0.00343884 Down 0.08663357 Fam134b "family with sequence similarity 134, member B" K14816|1|3e-117|426|tgu:100229493|pre-60S factor REI1 GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding GO:0006979//response to oxidative stress;GO:0007254//JNK cascade;GO:0007600//sensory perception;GO:0006915//apoptotic process;GO:0043549//regulation of kinase activity;GO:0006979//response to oxidative stress;GO:0007254//JNK cascade;GO:0007600//sensory perception;GO:0006915//apoptotic process;GO:0043549//regulation of kinase activity;GO:0006979//response to oxidative stress;GO:0007254//JNK cascade;GO:0007600//sensory perception;GO:0006915//apoptotic process;GO:0043549//regulation of kinase activity;GO:0006979//response to oxidative stress;GO:0007254//JNK cascade;GO:0007600//sensory perception;GO:0006915//apoptotic process;GO:0043549//regulation of kinase activity;GO:0006979//response to oxidative stress;GO:0007254//JNK cascade;GO:0007600//sensory perception;GO:0006915//apoptotic process;GO:0043549//regulation of kinase activity;GO:0006979//response to oxidative stress;GO:0007254//JNK cascade;GO:0007600//sensory perception;GO:0006915//apoptotic process;GO:0043549//regulation of kinase activity gi|474451729|ref|NP_001264246.1|/1.01817e-171/reticulophagy receptor Fam134b isoform 4 [Mus musculus] 17237 3290.07 93.42666667 93.12333333 -0.004691695 Down 0.086586558 Mgrn1 "mahogunin, ring finger 1" K10604|1|0.0|965|mmu:17237|E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27] GO:0005768//endosome;GO:0016020//membrane;GO:0005768//endosome;GO:0016020//membrane GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0007041//lysosomal transport;GO:0009968//negative regulation of signal transduction;GO:0016567//protein ubiquitination;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007041//lysosomal transport;GO:0009968//negative regulation of signal transduction;GO:0016567//protein ubiquitination;GO:0007186//G-protein coupled receptor signaling pathway gi|568994708|ref|XP_006521896.1|/0/PREDICTED: E3 ubiquitin-protein ligase MGRN1 isoform X3 [Mus musculus] 56451 1407 295.4133333 295.7 0.001399301 Up 0.086577156 Suclg1 "succinate-CoA ligase, GDP-forming, alpha subunit" K01899|1|4e-147|523|mmu:56451|succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5] GO:0019866//organelle inner membrane;GO:0030062//mitochondrial tricarboxylic acid cycle enzyme complex "GO:0004774//succinate-CoA ligase activity;GO:0046912//transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer;GO:0032550;GO:0046983//protein dimerization activity" GO:0043648//dicarboxylic acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0009060//aerobic respiration "gi|15029739|gb|AAH11087.1|/3.0953e-146/Succinate-CoA ligase, GDP-forming, alpha subunit [Mus musculus]" 11844 933 88.20333333 87.93 -0.00447771 Down 0.086548949 Arf5 ADP-ribosylation factor 5 K07940|1|2e-99|364|pale:102897918|ADP-ribosylation factor 5 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0006810//transport;GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0045184//establishment of protein localization gi|351705750|gb|EHB08669.1|/4.91476e-120/ADP-ribosylation factor 5 [Heterocephalus glaber] 625249 975.68 622.6766667 622.9366667 0.000602275 Up 0.086539546 Gpx4 glutathione peroxidase 4 K05361|1|1e-101|371|rno:29328|phospholipid-hydroperoxide glutathione peroxidase [EC:1.11.1.12] GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0044444//cytoplasmic part;GO:0012505//endomembrane system "GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0004601//peroxidase activity;GO:0072341//modified amino acid binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0004601//peroxidase activity;GO:0072341//modified amino acid binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0004601//peroxidase activity;GO:0072341//modified amino acid binding" GO:0044710;GO:0006954//inflammatory response;GO:0043627//response to estrogen;GO:0051276//chromosome organization;GO:0006790//sulfur compound metabolic process;GO:0044767//single-organism developmental process;GO:0048232//male gamete generation;GO:0042743//hydrogen peroxide metabolic process;GO:0044710;GO:0006954//inflammatory response;GO:0043627//response to estrogen;GO:0051276//chromosome organization;GO:0006790//sulfur compound metabolic process;GO:0044767//single-organism developmental process;GO:0048232//male gamete generation;GO:0042743//hydrogen peroxide metabolic process;GO:0044710;GO:0006954//inflammatory response;GO:0043627//response to estrogen;GO:0051276//chromosome organization;GO:0006790//sulfur compound metabolic process;GO:0044767//single-organism developmental process;GO:0048232//male gamete generation;GO:0042743//hydrogen peroxide metabolic process "gi|149034605|gb|EDL89342.1|/1.7446e-63/glutathione peroxidase 4, isoform CRA_c, partial [Rattus norvegicus]" 68953 927 84.25333333 84.45666667 0.003477543 Up 0.086398511 Chmp2a charged multivesicular body protein 2A K12191|1|4e-84|313|hgl:101722413|charged multivesicular body protein 2A GO:0005768//endosome GO:0005515//protein binding GO:0044765//single-organism transport;GO:0044763 gi|513010335|ref|XP_004866581.1|/3.35984e-83/PREDICTED: charged multivesicular body protein 2a isoform X1 [Heterocephalus glaber] 110611 6308.41 144.9 144.6966667 -0.002025908 Down 0.086398511 Hdlbp high density lipoprotein (HDL) binding protein K18756|1|1e-11|75.9|apla:101800706|protein bicaudal C GO:0034358//plasma lipoprotein particle;GO:0043231//intracellular membrane-bounded organelle;GO:0034358//plasma lipoprotein particle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0016125//sterol metabolic process;GO:0010876//lipid localization;GO:0051234//establishment of localization;GO:0016125//sterol metabolic process "gi|148708011|gb|EDL39958.1|/0/high density lipoprotein (HDL) binding protein, isoform CRA_h [Mus musculus]" 11651 2707 111.9933333 112.1833333 0.002445501 Up 0.086389108 Akt1 thymoma viral proto-oncogene 1 K04456|1|0.0|986|mmu:11651|RAC serine/threonine-protein kinase [EC:2.7.11.1] - - - - 224727 3808.61 95.84333333 95.66666667 -0.002661753 Down 0.086389108 Bag6 BCL2-associated athanogene 6 K10839|1|7e-06|56.2|hst:105192520|UV excision repair protein RAD23 GO:0043231//intracellular membrane-bounded organelle;GO:0072379;GO:0043231//intracellular membrane-bounded organelle;GO:0072379 GO:0043021//ribonucleoprotein complex binding;GO:0043130//ubiquitin binding;GO:0031072//heat shock protein binding;GO:0032403//protein complex binding;GO:0043021//ribonucleoprotein complex binding;GO:0043130//ubiquitin binding;GO:0031072//heat shock protein binding;GO:0032403//protein complex binding GO:0007417//central nervous system development;GO:0031647//regulation of protein stability;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006475//internal protein amino acid acetylation;GO:0031330;GO:0034976//response to endoplasmic reticulum stress;GO:0030323//respiratory tube development;GO:0048232//male gamete generation;GO:0045048//protein insertion into ER membrane;GO:0048002//antigen processing and presentation of peptide antigen;GO:0019941//modification-dependent protein catabolic process;GO:0007129//synapsis;GO:0007417//central nervous system development;GO:0031647//regulation of protein stability;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006475//internal protein amino acid acetylation;GO:0031330;GO:0034976//response to endoplasmic reticulum stress;GO:0030323//respiratory tube development;GO:0048232//male gamete generation;GO:0045048//protein insertion into ER membrane;GO:0048002//antigen processing and presentation of peptide antigen;GO:0019941//modification-dependent protein catabolic process;GO:0007129//synapsis gi|568999963|ref|XP_006524179.1|/0/PREDICTED: large proline-rich protein BAG6 isoform X6 [Mus musculus] 68316 957.41 116.3166667 116.51 0.002395955 Up 0.086389108 Apoo apolipoprotein O - - - - - 66915 458 71.88666667 72.08 0.003874803 Up 0.086389108 Myeov2 myeloma overexpressed 2 - - - - "gi|148708051|gb|EDL39998.1|/1.24615e-18/mCG20113, isoform CRA_b [Mus musculus]" 11820 3306.24 81.13 81.31 0.003197306 Up 0.086389108 App amyloid beta (A4) precursor protein K04520|1|0.0|755|cge:100689222|amyloid beta A4 protein GO:0031224//intrinsic component of membrane;GO:0031982//vesicle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0005819//spindle;GO:0030425//dendrite;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0031982//vesicle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0005819//spindle;GO:0030425//dendrite;GO:0044444//cytoplasmic part;GO:0031224//intrinsic component of membrane;GO:0031982//vesicle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0045202//synapse;GO:0005819//spindle;GO:0030425//dendrite;GO:0044444//cytoplasmic part GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0008047//enzyme activator activity;GO:0019904//protein domain specific binding;GO:0003676//nucleic acid binding;GO:0004866//endopeptidase inhibitor activity;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0008047//enzyme activator activity;GO:0019904//protein domain specific binding;GO:0003676//nucleic acid binding;GO:0004866//endopeptidase inhibitor activity;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0005539//glycosaminoglycan binding;GO:0008047//enzyme activator activity;GO:0019904//protein domain specific binding;GO:0003676//nucleic acid binding;GO:0004866//endopeptidase inhibitor activity GO:0016198//axon choice point recognition;GO:0007631//feeding behavior;GO:0007215//glutamate receptor signaling pathway;GO:0007416//synapse assembly;GO:0007268//chemical synaptic transmission;GO:0042551//neuron maturation;GO:0007420//brain development;GO:0043062//extracellular structure organization;GO:0016125//sterol metabolic process;GO:0035264//multicellular organism growth;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0010469//regulation of receptor activity;GO:0007618//mating;GO:0048668//collateral sprouting;GO:0010970//transport along microtubule;GO:0012502//induction of programmed cell death;GO:0022610;GO:0007626//locomotory behavior;GO:0051098//regulation of binding;GO:0006366//transcription from RNA polymerase II promoter;GO:0006464//cellular protein modification process;GO:0007632//visual behavior;GO:0070997//neuron death;GO:0016192//vesicle-mediated transport;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006950//response to stress;GO:0006412//translation;GO:0050905//neuromuscular process;GO:0031124//mRNA 3'-end processing;GO:0051345//positive regulation of hydrolase activity;GO:0016198//axon choice point recognition;GO:0007631//feeding behavior;GO:0007215//glutamate receptor signaling pathway;GO:0007416//synapse assembly;GO:0007268//chemical synaptic transmission;GO:0042551//neuron maturation;GO:0007420//brain development;GO:0043062//extracellular structure organization;GO:0016125//sterol metabolic process;GO:0035264//multicellular organism growth;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0010469//regulation of receptor activity;GO:0007618//mating;GO:0048668//collateral sprouting;GO:0010970//transport along microtubule;GO:0012502//induction of programmed cell death;GO:0022610;GO:0007626//locomotory behavior;GO:0051346//negative regulation of hydrolase activity;GO:0051098//regulation of binding;GO:0006366//transcription from RNA polymerase II promoter;GO:0006464//cellular protein modification process;GO:0007632//visual behavior;GO:0070997//neuron death;GO:0016192//vesicle-mediated transport;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006950//response to stress;GO:0006412//translation;GO:0050905//neuromuscular process;GO:0031124//mRNA 3'-end processing;GO:0051345//positive regulation of hydrolase activity;GO:0016198//axon choice point recognition;GO:0007631//feeding behavior;GO:0007215//glutamate receptor signaling pathway;GO:0007416//synapse assembly;GO:0007268//chemical synaptic transmission;GO:0042551//neuron maturation;GO:0007420//brain development;GO:0043062//extracellular structure organization;GO:0016125//sterol metabolic process;GO:0035264//multicellular organism growth;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0010469//regulation of receptor activity;GO:0007618//mating;GO:0048668//collateral sprouting;GO:0010970//transport along microtubule;GO:0012502//induction of programmed cell death;GO:0022610;GO:0007626//locomotory behavior;GO:0051098//regulation of binding;GO:0006366//transcription from RNA polymerase II promoter;GO:0006464//cellular protein modification process;GO:0007632//visual behavior;GO:0070997//neuron death;GO:0016192//vesicle-mediated transport;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006950//response to stress;GO:0006412//translation;GO:0050905//neuromuscular process;GO:0031124//mRNA 3'-end processing;GO:0051345//positive regulation of hydrolase activity "gi|13529548|gb|AAH05490.1|/0/App protein, partial [Mus musculus]" 68196 1178 90.86666667 91.04666667 0.002855043 Up 0.086389108 Hsbp1 heat shock factor binding protein 1 K19765|1|1e-34|149|mmu:68196|heat shock factor-binding protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043232 GO:0003712//transcription cofactor activity GO:0050896//response to stimulus;GO:0003012//muscle system process;GO:0006366//transcription from RNA polymerase II promoter gi|21311873|ref|NP_077181.1|/1.22882e-33/heat shock factor-binding protein 1 [Mus musculus] 19349 2175.05 211.26 211.0933333 -0.001138616 Down 0.086342096 Rab7 "RAB7, member RAS oncogene family" K07897|1|4e-115|418|shr:100923936|Ras-related protein Rab-7A GO:0042599//lamellar body;GO:0030666//endocytic vesicle membrane;GO:0005764//lysosome;GO:0048770;GO:0005768//endosome;GO:0042599//lamellar body;GO:0030666//endocytic vesicle membrane;GO:0005764//lysosome;GO:0048770;GO:0005768//endosome;GO:0042599//lamellar body;GO:0030666//endocytic vesicle membrane;GO:0005764//lysosome;GO:0048770;GO:0005768//endosome;GO:0042599//lamellar body;GO:0030666//endocytic vesicle membrane;GO:0005764//lysosome;GO:0048770;GO:0005768//endosome;GO:0042599//lamellar body;GO:0030666//endocytic vesicle membrane;GO:0005764//lysosome;GO:0048770;GO:0005768//endosome GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0017048//Rho GTPase binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0017048//Rho GTPase binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0017048//Rho GTPase binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0017048//Rho GTPase binding;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0017048//Rho GTPase binding GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0006623//protein targeting to vacuole;GO:0006906//vesicle fusion;GO:0007041//lysosomal transport;GO:0051452//intracellular pH reduction;GO:0009154//purine ribonucleotide catabolic process;GO:0002478;GO:0035556//intracellular signal transduction;GO:0001894//tissue homeostasis;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0006623//protein targeting to vacuole;GO:0006906//vesicle fusion;GO:0007041//lysosomal transport;GO:0051452//intracellular pH reduction;GO:0009154//purine ribonucleotide catabolic process;GO:0002478;GO:0035556//intracellular signal transduction;GO:0001894//tissue homeostasis;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0006623//protein targeting to vacuole;GO:0006906//vesicle fusion;GO:0007041//lysosomal transport;GO:0051452//intracellular pH reduction;GO:0009154//purine ribonucleotide catabolic process;GO:0002478;GO:0035556//intracellular signal transduction;GO:0001894//tissue homeostasis;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0006623//protein targeting to vacuole;GO:0006906//vesicle fusion;GO:0007041//lysosomal transport;GO:0051452//intracellular pH reduction;GO:0009154//purine ribonucleotide catabolic process;GO:0002478;GO:0035556//intracellular signal transduction;GO:0001894//tissue homeostasis;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0006623//protein targeting to vacuole;GO:0006906//vesicle fusion;GO:0007041//lysosomal transport;GO:0051452//intracellular pH reduction;GO:0009154//purine ribonucleotide catabolic process;GO:0002478;GO:0035556//intracellular signal transduction;GO:0001894//tissue homeostasis gi|34147513|ref|NP_004628.4|/3.01836e-114/ras-related protein Rab-7a [Homo sapiens] 20022 586 62.28666667 62.13 -0.003633313 Down 0.086313889 Polr2j polymerase (RNA) II (DNA directed) polypeptide J K03008|1|5e-61|235|gja:107107714|DNA-directed RNA polymerase II subunit RPB11 "GO:0016591//DNA-directed RNA polymerase II, holoenzyme" GO:0016301//kinase activity;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0034062//RNA polymerase activity GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006397//mRNA processing;GO:0044764;GO:0006289//nucleotide-excision repair;GO:0000377;GO:0006464//cellular protein modification process gi|528764275|gb|EPY83934.1|/4.52008e-62/ras GTPase-activating protein 4 isoform 1 [Camelus ferus] 107566 2014.16 47.97666667 47.81333333 -0.004919938 Down 0.086313889 Arl2bp ADP-ribosylation factor-like 2 binding protein K16742|1|3e-80|301|mmu:107566|ADP-ribosylation factor-like protein 2-binding protein GO:0005815//microtubule organizing center;GO:0005740//mitochondrial envelope;GO:0005815//microtubule organizing center;GO:0005740//mitochondrial envelope GO:0008047//enzyme activator activity;GO:0005488//binding;GO:0003712//transcription cofactor activity;GO:0030695//GTPase regulator activity;GO:0008047//enzyme activator activity;GO:0005488//binding;GO:0003712//transcription cofactor activity;GO:0030695//GTPase regulator activity GO:0019222//regulation of metabolic process;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0034504//protein localization to nucleus;GO:0019222//regulation of metabolic process;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0034504//protein localization to nucleus "gi|148679192|gb|EDL11139.1|/9.11702e-74/ADP-ribosylation factor-like 2 binding protein, isoform CRA_a, partial [Mus musculus]" 17227 990 0.76 0.746666667 -0.025535092 Down 0.086295084 Mcpt4 mast cell protease 4 K01329|1|1e-106|388|cge:100756053|chymase [EC:3.4.21.39];K08661|3|4e-95|350|mmu:17224|mast cell peptidase 1 [EC:3.4.21.-];K08662|4|3e-93|343|rno:29266|mast cell peptidase 2 [EC:3.4.21.-] GO:0044464 GO:0005539//glycosaminoglycan binding;GO:0033218//amide binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|11559289|dbj|BAB18732.1|/8.52518e-128/myonase [Mus musculus] 381306 2930 0.42 0.43 0.033947332 Up 0.086295084 BC055324 cDNA sequence BC055324 - - - - gi|568910994|ref|XP_006496974.1|/0/PREDICTED: uncharacterized protein C1orf112 homolog isoform X3 [Mus musculus] 414101 3595 0.533333333 0.543333333 0.026800059 Up 0.086295084 E130317F20Rik RIKEN cDNA E130317F20 gene - - - - - 214763 4090 0.583333333 0.596666667 0.032604665 Up 0.086295084 Mb21d1 Mab-21 domain containing 1 K17834|1|0.0|459|mmu:214763|cyclic GMP-AMP synthase [EC:2.7.7.86] - - - - 20845 4007 0.75 0.736666667 -0.025878632 Down 0.086295084 Star steroidogenic acute regulatory protein "K16931|1|7e-161|571|mmu:20845|steroidogenic acute regulatory protein, mitochondrial" GO:0042995//cell projection;GO:0005743//mitochondrial inner membrane;GO:0044297//cell body GO:0032934//sterol binding;GO:0015248//sterol transporter activity GO:0010467//gene expression;GO:0010720//positive regulation of cell development;GO:0006805//xenobiotic metabolic process;GO:0032868//response to insulin;GO:0048167//regulation of synaptic plasticity;GO:0008406//gonad development;GO:0001678//cellular glucose homeostasis;GO:0034341//response to interferon-gamma;GO:0031667//response to nutrient levels;GO:0009314//response to radiation;GO:0016125//sterol metabolic process;GO:0071870//cellular response to catecholamine stimulus;GO:0043279//response to alkaloid;GO:0030301//cholesterol transport;GO:0060416//response to growth hormone;GO:0006702//androgen biosynthetic process;GO:0046677//response to antibiotic;GO:0022410//circadian sleep/wake cycle process;GO:0000302//response to reactive oxygen species;GO:0034699//response to luteinizing hormone;GO:0071385//cellular response to glucocorticoid stimulus;GO:0050755//chemokine metabolic process;GO:0006721//terpenoid metabolic process;GO:0007417//central nervous system development;GO:0051591//response to cAMP;GO:0071363//cellular response to growth factor stimulus;GO:0042537//benzene-containing compound metabolic process;GO:0046686//response to cadmium ion;GO:0043066//negative regulation of apoptotic process;GO:0032354//response to follicle-stimulating hormone;GO:0097305//response to alcohol;GO:0035455//response to interferon-alpha;GO:0032496//response to lipopolysaccharide;GO:0006700//C21-steroid hormone biosynthetic process "gi|31543776|ref|NP_035615.2|/6.04423e-160/steroidogenic acute regulatory protein, mitochondrial precursor [Mus musculus]" 72789 6450 0.55 0.563333333 0.034557222 Up 0.086295084 Veph1 ventricular zone expressed PH domain-containing 1 K09566|1|6e-43|180|pxy:105383147|peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8] GO:0016020//membrane - - gi|148683584|gb|EDL15531.1|/0/ventricular zone expressed PH domain homolog 1 (zebrafish) [Mus musculus] 230809 4639 0.596666667 0.583333333 -0.032604665 Down 0.086295084 Pdik1l PDLIM1 interacting kinase 1 like K17539|1|0.0|694|ocu:100346897|serine/threonine-protein kinase PDIK1L [EC:2.7.11.1] - - - "gi|148698073|gb|EDL30020.1|/0/PDLIM1 interacting kinase 1 like, isoform CRA_b, partial [Mus musculus]" 22337 4354 0.313333333 0.306666667 -0.031026896 Down 0.086295084 Vdr vitamin D receptor K08539|1|0.0|801|mmu:22337|vitamin D3 receptor GO:0000790//nuclear chromatin;GO:0042383//sarcolemma;GO:0044444//cytoplasmic part "GO:0004879//RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding;GO:0005496//steroid binding;GO:0042974//retinoic acid receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0046914//transition metal ion binding" GO:0022603//regulation of anatomical structure morphogenesis;GO:0032989;GO:0001893//maternal placenta development;GO:0022600//digestive system process;GO:0007589//body fluid secretion;GO:0030216//keratinocyte differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0043627//response to estrogen;GO:0010038//response to metal ion;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0032768;GO:0010979;GO:0006816//calcium ion transport;GO:0006875//cellular metal ion homeostasis gi|31543944|ref|NP_033530.2|/0/vitamin D3 receptor [Mus musculus] 105988 6630 0.283333333 0.276666667 -0.034351505 Down 0.086295084 Espl1 "extra spindle pole bodies 1, separase" K02365|1|0.0|3994|mmu:105988|separase [EC:3.4.22.49] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0007127//meiosis I;GO:0019538//protein metabolic process;GO:0000819//sister chromatid segregation;GO:0007051//spindle organization "gi|148672045|gb|EDL03992.1|/0/extra spindle poles-like 1 (S. cerevisiae), isoform CRA_b, partial [Mus musculus]" 70291 2539 0.49 0.5 0.029146346 Up 0.086295084 Mkrn2os "makorin, ring finger protein 2, opposite strand" - - - - gi|160333472|ref|NP_001094901.1|/7.57537e-126/MKRN2 opposite strand protein [Mus musculus] 320440 7977 0.48 0.49 0.029747343 Up 0.086295084 9530091C08Rik RIKEN cDNA 9530091C08 gene - - - - gi|26338105|dbj|BAC32738.1|/8.42886e-55/unnamed protein product [Mus musculus] 68743 5421 0.34 0.333333333 -0.028569152 Down 0.086295084 Anln "anillin, actin binding protein" K18621|1|0.0|1983|mmu:68743|actin-binding protein anillin - - - "gi|148693327|gb|EDL25274.1|/0/anillin, actin binding protein (scraps homolog, Drosophila), isoform CRA_b, partial [Mus musculus]" 242466 10514 0.31 0.316666667 0.030696797 Up 0.086295084 Zfp462 zinc finger protein 462 K09228|1|9e-41|173|cmk:103178353|KRAB domain-containing zinc finger protein - - - gi|114431238|ref|NP_766455.2|/0/zinc finger protein 462 [Mus musculus] 18986 12906 0.633333333 0.62 -0.030696797 Down 0.086295084 Pou2f1 "POU domain, class 2, transcription factor 1" "K09364|1|5e-147|526|mmu:18986|POU domain transcription factor, class 2" GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0003677//DNA binding;GO:0003677//DNA binding;GO:0003677//DNA binding;GO:0003677//DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0043584//nose development;GO:0002089//lens morphogenesis in camera-type eye;GO:0006366//transcription from RNA polymerase II promoter;GO:0043584//nose development;GO:0002089//lens morphogenesis in camera-type eye;GO:0006366//transcription from RNA polymerase II promoter;GO:0043584//nose development;GO:0002089//lens morphogenesis in camera-type eye;GO:0006366//transcription from RNA polymerase II promoter;GO:0043584//nose development;GO:0002089//lens morphogenesis in camera-type eye "gi|114431252|ref|NP_035267.2|/1.30496e-153/POU domain, class 2, transcription factor 1 isoform A [Mus musculus] " 14221 2446 0.323333333 0.33 0.029443778 Up 0.086295084 Fjx1 four jointed box 1 (Drosophila) K16674|1|0.0|804|mmu:14221|four-jointed box protein 1 GO:0044421 - - gi|47059108|ref|NP_034348.2|/0/four-jointed box protein 1 precursor [Mus musculus] 319535 5920 0.326666667 0.333333333 0.029146346 Up 0.086295084 Zfp182 zinc finger protein 182 K09228|1|0.0|1333|mmu:319535|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148668403|gb|EDL00727.1|/0/zinc finger protein 182, isoform CRA_a [Mus musculus]" 277973 5222 0.543333333 0.556666667 0.034976138 Up 0.086295084 Slc9a5 "solute carrier family 9 (sodium/hydrogen exchanger), member 5" "K14723|1|0.0|1470|mmu:277973|solute carrier family 9 (sodium/hydrogen exchanger), member 5" GO:0031224//intrinsic component of membrane GO:0005451//monovalent cation:proton antiporter activity GO:0044763;GO:0055067;GO:0006818//hydrogen transport;GO:0006814//sodium ion transport gi|124486739|ref|NP_001074801.1|/0/sodium/hydrogen exchanger 5 precursor [Mus musculus] 100316839 120 0.58 0.566666667 -0.03355256 Down 0.086295084 Mir1191 microRNA 1191 - - - - - 319562 3406 0.373333333 0.366666667 -0.025995209 Down 0.086295084 9630028B13Rik RIKEN cDNA 9630028B13 gene "K14697|1|9e-56|221|phd:102321434|solute carrier family 30 (zinc transporter), member 10" - - - - 373864 7635 0.48 0.49 0.029747343 Up 0.086295084 Col27a1 "collagen, type XXVII, alpha 1" "K19721|1|0.0|1614|mmu:373864|collagen, type V/XI/XXIV/XXVII, alpha" - - - - 21778 4317 0.473333333 0.463333333 -0.030806047 Down 0.086295084 Tex9 testis expressed gene 9 K10352|1|6e-11|73.2|myb:102241398|myosin heavy chain - - - "gi|148694311|gb|EDL26258.1|/0/testis expressed gene 9, isoform CRA_e [Mus musculus]" 28015 2258.94 137.2733333 137.1233333 -0.00157731 Down 0.08627628 Polr2m polymerase (RNA) II (DNA directed) polypeptide M - GO:0044297//cell body;GO:0012505//endomembrane system;GO:0044451;GO:0044297//cell body;GO:0012505//endomembrane system;GO:0044451 GO:0034062//RNA polymerase activity;GO:0034062//RNA polymerase activity GO:0051643//endoplasmic reticulum localization;GO:0010467//gene expression;GO:0051643//endoplasmic reticulum localization;GO:0010467//gene expression gi|30519919|ref|NP_848717.1|/3.04529e-147/DNA-directed RNA polymerase II subunit GRINL1A isoform 1 [Mus musculus] 75687 4152 41.85 41.71333333 -0.004719019 Down 0.086229268 Fam65a "family with sequence similarity 65, member A" K10385|1|3e-07|60.8|rno:502541|loricrin GO:0044424 - - gi|28972878|dbj|BAC65855.1|/0/mKIAA1930 protein [Mus musculus] 15469 1347.59 41.98 42.12 0.00480327 Up 0.086229268 Prmt1 protein arginine N-methyltransferase 1 K11434|1|0.0|675|rno:60421|type I protein arginine methyltransferase [EC:2.1.1.319] - - - - 208263 4302 45.36666667 45.49666667 0.004128188 Up 0.086154049 Tor1aip1 torsin A interacting protein 1 - GO:0012505//endomembrane system;GO:0031967;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0019866//organelle inner membrane;GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0044763;GO:0006998//nuclear envelope organization;GO:0033365//protein localization to organelle gi|229608944|ref|NP_659040.2|/0/torsin-1A-interacting protein 1 isoform 2 [Mus musculus] 26396 2387 50.67333333 50.80333333 0.003696425 Up 0.086154049 Map2k2 mitogen-activated protein kinase kinase 2 K04369|1|0.0|736|mmu:26396|mitogen-activated protein kinase kinase 2 [EC:2.7.12.2] GO:0015630//microtubule cytoskeleton;GO:0005924//cell-substrate adherens junction;GO:0005768//endosome;GO:0044439;GO:0044459 GO:0032550;GO:0030295//protein kinase activator activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0019904//protein domain specific binding GO:0033043//regulation of organelle organization;GO:0040017//positive regulation of locomotion;GO:0043408//regulation of MAPK cascade;GO:0018105//peptidyl-serine phosphorylation;GO:0045860//positive regulation of protein kinase activity;GO:0032386//regulation of intracellular transport gi|31560267|ref|NP_075627.2|/0/dual specificity mitogen-activated protein kinase kinase 2 [Mus musculus] 19043 2934.55 38.88 38.76 -0.004459648 Down 0.086069427 Ppm1b "protein phosphatase 1B, magnesium dependent, beta isoform" K04461|1|0.0|791|mmu:19043|protein phosphatase 1B [EC:3.1.3.16] - GO:0004721//phosphoprotein phosphatase activity;GO:0046914//transition metal ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0046914//transition metal ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0046914//transition metal ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0046914//transition metal ion binding GO:0006470//protein dephosphorylation;GO:0006470//protein dephosphorylation;GO:0006470//protein dephosphorylation;GO:0006470//protein dephosphorylation "gi|148706646|gb|EDL38593.1|/0/mCG15599, isoform CRA_e, partial [Mus musculus]" 11737 2105 56.76333333 56.87333333 0.002793051 Up 0.085928391 Anp32a "acidic (leucine-rich) nuclear phosphoprotein 32 family, member A" K18646|1|3e-72|275|mmu:11737|acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D - - - - 69113 1247 31.28666667 31.2 -0.004001931 Down 0.085777953 Alkbh3 "alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase" K10860|1|1e-171|604|mmu:69113|alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 [EC:1.14.11.-] - - - - 225363 3718 30.18333333 30.27666667 0.004454239 Up 0.085777953 Etf1 eukaryotic translation termination factor 1 K03265|1|0.0|870|acs:100566787|peptide chain release factor subunit 1 GO:0044444//cytoplasmic part GO:0003747//translation release factor activity;GO:0043021//ribonucleoprotein complex binding GO:0008213;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006415//translational termination gi|560964464|ref|XP_006204645.1|/0/PREDICTED: eukaryotic peptide chain release factor subunit 1 [Vicugna pacos] 15452 1349 29.08 28.99333333 -0.004306061 Down 0.085777953 Hprt hypoxanthine guanine phosphoribosyl transferase K00760|1|2e-122|441|mmu:15452|hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] - - - gi|96975138|ref|NP_038584.2|/1.91256e-121/hypoxanthine-guanine phosphoribosyltransferase [Mus musculus] 14673 1880 81.31333333 81.23333333 -0.001420092 Down 0.085618113 Gna12 "guanine nucleotide binding protein, alpha 12" K04346|1|0.0|667|mmu:14673|guanine nucleotide-binding protein subunit alpha-12 - - - gi|6754006|ref|NP_034432.1|/0/guanine nucleotide-binding protein subunit alpha-12 [Mus musculus] 11430 3992 101.4433333 101.5233333 0.001137286 Up 0.085618113 Acox1 "acyl-Coenzyme A oxidase 1, palmitoyl" K00232|1|0.0|1271|mmu:11430|acyl-CoA oxidase [EC:1.3.3.6] GO:0044439;GO:0044439 GO:0003997//acyl-CoA oxidase activity;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0050660//flavin adenine dinucleotide binding;GO:0003997//acyl-CoA oxidase activity;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0050660//flavin adenine dinucleotide binding GO:0007031//peroxisome organization;GO:0006692;GO:0048878//chemical homeostasis;GO:0048232//male gamete generation;GO:0006635//fatty acid beta-oxidation;GO:0032846;GO:0007031//peroxisome organization;GO:0006692;GO:0048878//chemical homeostasis;GO:0048232//male gamete generation;GO:0006635//fatty acid beta-oxidation;GO:0032846 gi|66793429|ref|NP_056544.2|/0/peroxisomal acyl-coenzyme A oxidase 1 isoform 1 [Mus musculus] 13518 17939.92 23.16333333 23.08333333 -0.00499131 Down 0.085618113 Dst dystonin K10382|1|0.0|1.363e+04|mmu:13518|dystonin GO:0044291//cell-cell contact zone;GO:0032432//actin filament bundle;GO:0044432;GO:0031672//A band;GO:0045111//intermediate filament cytoskeleton;GO:0005874//microtubule;GO:0031674//I band;GO:0005924//cell-substrate adherens junction;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0030424//axon;GO:0012505//endomembrane system;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0030055//cell-substrate junction;GO:0016323//basolateral plasma membrane;GO:0031672//A band;GO:0045111//intermediate filament cytoskeleton;GO:0005874//microtubule;GO:0031674//I band;GO:0031224//intrinsic component of membrane;GO:0005578//proteinaceous extracellular matrix;GO:0031090//organelle membrane;GO:0030424//axon;GO:0012505//endomembrane system GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0008017//microtubule binding;GO:0042802//identical protein binding;GO:0005102//receptor binding;GO:0032550;GO:0008017//microtubule binding;GO:0015405;GO:0042802//identical protein binding GO:0007163//establishment or maintenance of cell polarity;GO:0031109//microtubule polymerization or depolymerization;GO:0007044//cell-substrate junction assembly;GO:0022610;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0022402//cell cycle process;GO:0008088//axo-dendritic transport;GO:0006950//response to stress;GO:0007166//cell surface receptor signaling pathway;GO:0007163//establishment or maintenance of cell polarity;GO:0031109//microtubule polymerization or depolymerization;GO:0007044//cell-substrate junction assembly;GO:0022610;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0022402//cell cycle process;GO:0008088//axo-dendritic transport;GO:0006950//response to stress gi|111154076|ref|NP_604443.2|/0/dystonin isoform 2 [Mus musculus] 68514 2310 32.83666667 32.76 -0.003372326 Down 0.085618113 Micu2 mitochondrial calcium uptake 2 "K20028|1|2e-20|103|oaa:100078401|palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225];K15105|2|7e-09|65.5|soc:105193077|solute carrier family 25 (mitochondrial aspartate/glutamate transporter), member 12/13" GO:0043231//intracellular membrane-bounded organelle GO:0046872//metal ion binding - gi|74191139|dbj|BAE39401.1|/0/unnamed protein product [Mus musculus] 20719 1470.4 47.28 47.35666667 0.002337501 Up 0.085618113 Serpinb6a "serine (or cysteine) peptidase inhibitor, clade B, member 6a" K13963|1|0.0|724|mmu:20719|serpin B - - - "gi|148708925|gb|EDL40871.1|/0/serine (or cysteine) peptidase inhibitor, clade B, member 6a, isoform CRA_b, partial [Mus musculus]" 622404 814 27.23 27.15 -0.004244784 Down 0.085618113 Ccdc107 coiled-coil domain containing 107 - GO:0031224//intrinsic component of membrane - - gi|85702296|ref|NP_001033002.1|/2.37827e-116/coiled-coil domain-containing protein 107 precursor [Mus musculus] 12537 2589 25.59666667 25.67333333 0.004314675 Up 0.085618113 Cdk11b cyclin-dependent kinase 11B K08818|1|0.0|840|mmu:12537|cell division cycle 2-like [EC:2.7.11.22] GO:0043231//intracellular membrane-bounded organelle GO:0032550;GO:0004674//protein serine/threonine kinase activity GO:0012501//programmed cell death;GO:0006464//cellular protein modification process;GO:0007067//mitotic nuclear division;GO:0006796//phosphate-containing compound metabolic process;GO:0006397//mRNA processing;GO:0001701//in utero embryonic development "gi|148683072|gb|EDL15019.1|/0/cell division cycle 2-like 1, isoform CRA_c, partial [Mus musculus]" 15488 2685 50.87 50.94333333 0.002078267 Up 0.085420663 Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 "K12405|1|0.0|1390|mmu:15488|3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.35 4.2.1.107 4.2.1.119]" - - - - 69757 2213 24.51 24.43666667 -0.004322979 Down 0.085420663 Leng1 leukocyte receptor cluster (LRC) member 1 K12580|1|4e-18|95.9|ptr:456279|CCR4-NOT transcription complex subunit 3 - - - gi|21312402|ref|NP_081479.1|/4.81352e-81/leukocyte receptor cluster member 1 homolog [Mus musculus] 19330 3670 21.85 21.91666667 0.004395114 Up 0.085420663 Rab18 "RAB18, member RAS oncogene family" K07910|1|2e-114|417|mmu:19330|Ras-related protein Rab-18 GO:0044464;GO:0016020//membrane;GO:0044464;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0016192//vesicle-mediated transport;GO:0007417//central nervous system development;GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0007423//sensory organ development;GO:0045184//establishment of protein localization;GO:0016192//vesicle-mediated transport;GO:0007417//central nervous system development;GO:0035556//intracellular signal transduction;GO:0009154//purine ribonucleotide catabolic process;GO:0007423//sensory organ development;GO:0045184//establishment of protein localization gi|510936915|ref|NP_001265376.1|/4.42201e-117/ras-related protein Rab-18 isoform 1 [Mus musculus] 19205 3098.52 25.57 25.50333333 -0.003766338 Down 0.085420663 Ptbp1 polypyrimidine tract binding protein 1 K13218|1|0.0|912|mmu:19205|polypyrimidine tract-binding protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0036094//small molecule binding;GO:0043566//structure-specific DNA binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0036094//small molecule binding;GO:0043566//structure-specific DNA binding;GO:0003723//RNA binding;GO:0004518//nuclease activity;GO:0036094//small molecule binding;GO:0043566//structure-specific DNA binding "GO:0042692//muscle cell differentiation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0042692//muscle cell differentiation;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0042692//muscle cell differentiation;GO:0000380//alternative mRNA splicing, via spliceosome" gi|116517301|ref|NP_001070831.1|/0/polypyrimidine tract-binding protein 1 isoform 1 [Mus musculus] 245305 1264 0.386666667 0.393333333 0.024662054 Up 0.085317236 B230307C23Rik RIKEN cDNA B230307C23 gene K09228|1|5e-42|174|mmu:630579|KRAB domain-containing zinc finger protein - - - - 70419 1523 0.426666667 0.433333333 0.022367813 Up 0.085317236 2810408A11Rik RIKEN cDNA 2810408A11 gene K16833|1|5e-31|131|cjc:103793080|protein phosphatase inhibitor 2 - - GO:0050794//regulation of cellular process gi|568975725|ref|XP_006534234.1|/0/PREDICTED: protein phosphatase inhibitor 2-like isoform X1 [Mus musculus] 68617 7238 0.75 0.76 0.019108823 Up 0.085317236 Mtcl1 microtubule crosslinking factor 1 K01895|1|2e-66|258|apla:101803542|acetyl-CoA synthetase [EC:6.2.1.1];K20283|2|2e-09|68.9|mde:101892550|golgin subfamily A member 4;K10352|3|5e-09|67.8|asn:106722932|myosin heavy chain;K10388|4|8e-09|67.0|dre:100321011|plectin - - - gi|166235131|ref|NP_766551.3|/0/microtubule cross-linking factor 1 isoform 2 [Mus musculus] 329735 5428 0.733333333 0.723333333 -0.019808481 Down 0.085317236 4933431E20Rik RIKEN cDNA 4933431E20 gene K17277|1|3e-30|137|mmu:99662|epidermal growth factor receptor kinase substrate 8 - - - - 16180 4388.08 0.783333333 0.796666667 0.024349861 Up 0.085317236 Il1rap interleukin 1 receptor accessory protein K04723|1|0.0|1215|cge:100771447|interleukin 1 receptor accessory protein GO:0032991//macromolecular complex;GO:0016021//integral component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0044424;GO:0032991//macromolecular complex;GO:0016021//integral component of membrane;GO:0044424;GO:0031224//intrinsic component of membrane;GO:0032991//macromolecular complex;GO:0044424 GO:0005126//cytokine receptor binding;GO:0004896//cytokine receptor activity;GO:0019838//growth factor binding;GO:0005126//cytokine receptor binding;GO:0004896//cytokine receptor activity;GO:0019838//growth factor binding;GO:0005126//cytokine receptor binding;GO:0004896//cytokine receptor activity;GO:0019838//growth factor binding;GO:0004896//cytokine receptor activity;GO:0005126//cytokine receptor binding;GO:0019838//growth factor binding GO:0006952//defense response;GO:0032623//interleukin-2 production;GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway;GO:0065003;GO:0006952//defense response;GO:0032623//interleukin-2 production;GO:0007166//cell surface receptor signaling pathway;GO:0006952//defense response;GO:0032623//interleukin-2 production;GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway;GO:0065003;GO:0032623//interleukin-2 production;GO:0007166//cell surface receptor signaling pathway gi|74197313|dbj|BAE43382.1|/0/unnamed protein product [Mus musculus] 319982 3567 0.606666667 0.613333333 0.015767316 Up 0.085317236 5930430L01Rik RIKEN cDNA 5930430L01 gene - - - - gi|148673909|gb|EDL05856.1|/2.07883e-19/mCG147171 [Mus musculus] 330938 5627 1.26 1.273333333 0.015186404 Up 0.085317236 Dixdc1 DIX domain containing 1 K02353|1|2e-12|78.6|hmg:100205784|segment polarity protein dishevelled - - - gi|901694072|ref|NP_001297998.1|/0/dixin isoform 2 [Mus musculus] 11481 10594 0.926666667 0.913333333 -0.02090899 Down 0.085317236 Acvr2b activin receptor IIB K13596|1|0.0|1046|mmu:11481|activin receptor type-2B [EC:2.7.11.30] - - - - 387247 103 0.716666667 0.726666667 0.019991475 Up 0.085317236 Mirlet7d microRNA let7d - - - - - 212285 7363 0.6 0.59 -0.024247546 Down 0.085317236 Arap2 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2" "K18440|1|0.0|3355|mmu:212285|Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2" - - - "gi|189458894|ref|NP_848494.2|/0/arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 [Mus musculus] " 100628594 86 0.96 0.95 -0.015106892 Down 0.085317236 Mir3572 microRNA 3572 - - - - - 18762 4311 0.73 0.74 0.019628807 Up 0.085317236 Prkcz "protein kinase C, zeta" K18952|1|0.0|1226|mmu:18762|atypical protein kinase C zeta type [EC:2.7.11.13] GO:0043296//apical junction complex;GO:0034399//nuclear periphery;GO:0005884//actin filament;GO:0012505//endomembrane system;GO:0044459;GO:0043209//myelin sheath;GO:0044448;GO:0043296//apical junction complex;GO:0034399//nuclear periphery;GO:0005884//actin filament;GO:0012505//endomembrane system;GO:0044459;GO:0043209//myelin sheath;GO:0044448 GO:0004674//protein serine/threonine kinase activity;GO:0019900//kinase binding;GO:0032550;GO:0046914//transition metal ion binding;GO:0016247//channel regulator activity;GO:0004674//protein serine/threonine kinase activity;GO:0019900//kinase binding;GO:0032550;GO:0046914//transition metal ion binding;GO:0016247//channel regulator activity GO:0001952//regulation of cell-matrix adhesion;GO:0002726//positive regulation of T cell cytokine production;GO:0006915//apoptotic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0048167//regulation of synaptic plasticity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0010828//positive regulation of glucose transport;GO:0032147//activation of protein kinase activity;GO:0048870//cell motility;GO:0010518//positive regulation of phospholipase activity;GO:0007009//plasma membrane organization;GO:0045064//T-helper 2 cell differentiation;GO:0006952//defense response;GO:0007613//memory;GO:0043410//positive regulation of MAPK cascade;GO:0007163//establishment or maintenance of cell polarity;GO:0001933//negative regulation of protein phosphorylation;GO:0007599//hemostasis;GO:0050715//positive regulation of cytokine secretion;GO:0051648//vesicle localization;GO:0008283//cell proliferation;GO:0043086//negative regulation of catalytic activity;GO:0051259//protein oligomerization;GO:0030036//actin cytoskeleton organization;GO:0045838//positive regulation of membrane potential;GO:0008286//insulin receptor signaling pathway;GO:0001952//regulation of cell-matrix adhesion;GO:0002726//positive regulation of T cell cytokine production;GO:0006915//apoptotic process;GO:0048167//regulation of synaptic plasticity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0010828//positive regulation of glucose transport;GO:0032147//activation of protein kinase activity;GO:0048870//cell motility;GO:0010518//positive regulation of phospholipase activity;GO:0007009//plasma membrane organization;GO:0045064//T-helper 2 cell differentiation;GO:0006952//defense response;GO:0007613//memory;GO:0043410//positive regulation of MAPK cascade;GO:0007163//establishment or maintenance of cell polarity;GO:0001933//negative regulation of protein phosphorylation;GO:0050715//positive regulation of cytokine secretion;GO:0051648//vesicle localization;GO:0008283//cell proliferation;GO:0043086//negative regulation of catalytic activity;GO:0051259//protein oligomerization;GO:0030036//actin cytoskeleton organization;GO:0045838//positive regulation of membrane potential;GO:0008286//insulin receptor signaling pathway gi|568930805|ref|XP_006538718.1|/0/PREDICTED: protein kinase C zeta type isoform X3 [Mus musculus] 77533 2747 0.483333333 0.49 0.019763255 Up 0.085317236 C030034I22Rik RIKEN cDNA C030034I22 gene - - - - gi|74138355|dbj|BAE38036.1|/4.35947e-42/unnamed protein product [Mus musculus] 212728 5060 0.626666667 0.636666667 0.022839976 Up 0.085317236 Gm17296 TAR RNA binding protein 1 - - - - gi|229577450|ref|NP_001153379.1|/0/probable methyltransferase TARBP1 [Mus musculus] 245638 5907 0.61 0.603333333 -0.015853951 Down 0.085317236 Tbc1d8b "TBC1 domain family, member 8B" K19951|1|0.0|1788|oaa:100082358|TBC1 domain family member 9 GO:0044464 GO:0046872//metal ion binding - gi|125630636|ref|NP_001074968.1|/0/TBC1 domain family member 8B [Mus musculus] 382019 5651 0.72 0.73 0.019899557 Up 0.085317236 Zfp882 zinc finger protein 882 K09228|1|0.0|991|ngi:103734776|KRAB domain-containing zinc finger protein - - - gi|262263349|ref|NP_001160117.1|/0/zinc finger protein 882 [Mus musculus] 69627 1315 1.046666667 1.033333333 -0.018496344 Down 0.085317236 Fam89a "family with sequence similarity 89, member A" - - - - "gi|148679834|gb|EDL11781.1|/3.76627e-74/mCG51212, partial [Mus musculus]" 73420 2719 0.896666667 0.883333333 -0.021613813 Down 0.085317236 Ccsap "centriole, cilia and spindle associated protein" "K16454|1|3e-111|405|mmu:73420|centriole, cilia and spindle-associated protein" GO:0031513//nonmotile primary cilium;GO:0043005//neuron projection;GO:0005930//axoneme;GO:0005813//centrosome - GO:0032502//developmental process "gi|110625952|ref|NP_082812.1|/2.16397e-110/centriole, cilia and spindle-associated protein [Mus musculus]" 319352 2075 0.643333333 0.636666667 -0.015028209 Down 0.085317236 Pianp PILR alpha associated neural protein - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|149049445|gb|EDM01899.1|/1.34732e-101/similar to RIKEN cDNA C530028O21 gene, isoform CRA_a [Rattus norvegicus]" 60364 2336 1.013333333 1.026666667 0.018859027 Up 0.085317236 Donson downstream neighbor of SON - GO:0043231//intracellular membrane-bounded organelle - GO:0032502//developmental process "gi|148671867|gb|EDL03814.1|/0/downstream neighbor of SON, isoform CRA_a, partial [Mus musculus]" 74637 2781 0.85 0.84 -0.017073513 Down 0.085317236 Shpk sedoheptulokinase K11214|1|0.0|928|mmu:74637|sedoheptulokinase [EC:2.7.1.14] - - - - 68214 1305 0.576666667 0.586666667 0.024803391 Up 0.085317236 Gsto2 glutathione S-transferase omega 2 K00799|1|9e-150|532|mmu:68214|glutathione S-transferase [EC:2.5.1.18] GO:0044424;GO:0044424 GO:0030614;GO:0015038//glutathione disulfide oxidoreductase activity;GO:0030614;GO:0015038//glutathione disulfide oxidoreductase activity GO:0005996//monosaccharide metabolic process;GO:0044237//cellular metabolic process;GO:0046685//response to arsenic-containing substance;GO:0044710;GO:0005996//monosaccharide metabolic process;GO:0044237//cellular metabolic process;GO:0046685//response to arsenic-containing substance;GO:0044710 "gi|148710100|gb|EDL42046.1|/3.66329e-156/glutathione S-transferase omega 2, isoform CRA_c, partial [Mus musculus]" 209378 7942 0.88 0.89 0.016301812 Up 0.085317236 Itih5 inter-alpha (globulin) inhibitor H5 K19015|1|7e-145|519|cmk:103187925|inter-alpha-trypsin inhibitor heavy chain H2 - - - - 66808 2268 1.28 1.266666667 -0.015106892 Down 0.085317236 9030624G23Rik RIKEN cDNA 9030624G23 gene K19695|1|9e-36|141|cmk:103172717|neurocalcin delta - - - gi|374532832|ref|NP_001243418.1|/4.63272e-87/uncharacterized protein LOC66808 [Mus musculus] 72828 3243 0.62 0.626666667 0.015430041 Up 0.085317236 Ubash3b "ubiquitin associated and SH3 domain containing, B" K18993|1|0.0|1293|mmu:72828|ubiquitin-associated and SH3 domain-containing protein [EC:3.1.3.48] GO:0043231//intracellular membrane-bounded organelle GO:0004721//phosphoprotein phosphatase activity GO:0001933//negative regulation of protein phosphorylation;GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0010522//regulation of calcium ion transport into cytosol;GO:0006470//protein dephosphorylation gi|28849905|ref|NP_789830.1|/0/ubiquitin-associated and SH3 domain-containing protein B [Mus musculus] 68318 5185 0.406666667 0.413333333 0.023458973 Up 0.085317236 Aph1c "aph1 homolog C, gamma secretase subunit" K06172|1|7e-135|485|mmu:68318|anterior pharynx defective 1 - - - - 668489 1288 0.666666667 0.676666667 0.021479727 Up 0.085317236 Gm9199 glycine cleavage system protein H (aminomethyl carrier) pseudogene K02437|1|6e-48|112|rro:104671642|glycine cleavage system H protein - - - "gi|676265087|gb|KFO21352.1|/8.52144e-48/Glycine cleavage system H protein, mitochondrial [Fukomys damarensis]" 72834 1365 0.62 0.61 -0.023458973 Down 0.085317236 2810468N07Rik RIKEN cDNA 2810468N07 gene - - - - - 245026 7098 0.446666667 0.44 -0.021695071 Down 0.085317236 Col6a6 "collagen, type VI, alpha 6" "K06238|1|0.0|2277|mmu:245026|collagen, type VI, alpha" - - - - 224419 1652 0.956666667 0.97 0.019968416 Up 0.085317236 Map3k7cl Map3k7 C-terminal like K04427|1|2e-29|132|cmk:103183630|mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25] - - - gi|7717312|emb|CAB90434.1|/5.86763e-86/TGF-beta-activated kinase like [Homo sapiens] 245000 8074 0.736666667 0.726666667 -0.019718235 Down 0.085317236 Atr ataxia telangiectasia and Rad3 related K06640|1|0.0|5151|mmu:245000|serine/threonine-protein kinase ATR [EC:2.7.11.1] GO:0000803//sex chromosome GO:0004672//protein kinase activity;GO:0032404 "GO:0042221//response to chemical;GO:0010332//response to gamma radiation;GO:0007569//cell aging;GO:0009411//response to UV;GO:0006468//protein phosphorylation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0051098//regulation of binding;GO:0006260//DNA replication" gi|189339266|ref|NP_063917.1|/0/serine/threonine-protein kinase ATR [Mus musculus] 69993 3086.86 0.926666667 0.94 0.02061028 Up 0.085317236 Chn2 chimerin 2 "K02649|1|7e-37|158|spu:588766|phosphoinositide-3-kinase, regulatory subunit;K10360|3|8e-33|145|tca:656579|myosin IX;K13736|4|8e-33|145|xma:102217709|Rho GTPase-activating protein 10" GO:0044464;GO:0044464 GO:0043169//cation binding GO:0007165//signal transduction;GO:0043087//regulation of GTPase activity;GO:0007165//signal transduction gi|902763299|ref|NP_001298062.1|/2.03249e-164/beta-chimaerin isoform 3 [Mus musculus] 102465150 117 0.593333333 0.586666667 -0.016301812 Down 0.085317236 Mir6244 microRNA 6244 K18668|1|1e-16|87.0|mmu:244871|ribonuclease ZC3H12 [EC:3.1.-.-] - GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding - "gi|148693839|gb|EDL25786.1|/1.06455e-15/mCG4830, partial [Mus musculus]" 12448 3026 0.83 0.84 0.017277991 Up 0.085317236 Ccne2 cyclin E2 K06626|1|0.0|781|mmu:12448|cyclin E GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0019900//kinase binding;GO:0019887//protein kinase regulator activity;GO:0019900//kinase binding;GO:0019887//protein kinase regulator activity;GO:0019900//kinase binding;GO:0019887//protein kinase regulator activity GO:0006259//DNA metabolic process;GO:0051726//regulation of cell cycle;GO:0044772//mitotic cell cycle phase transition;GO:0006259//DNA metabolic process;GO:0051726//regulation of cell cycle;GO:0044772//mitotic cell cycle phase transition;GO:0006259//DNA metabolic process;GO:0051726//regulation of cell cycle;GO:0044772//mitotic cell cycle phase transition gi|6753312|ref|NP_033960.1|/0/G1/S-specific cyclin-E2 isoform 2 [Mus musculus] 77219 3124.42 69.09333333 69.03333333 -0.001253367 Down 0.08525142 Ptgr2 prostaglandin reductase 2 K13949|1|0.0|662|mmu:77219|prostaglandin reductase 2 [EC:1.3.1.48] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0006692;GO:0006692;GO:0006692 "gi|148670827|gb|EDL02774.1|/0/zinc binding alcohol dehydrogenase, domain containing 1, isoform CRA_e, partial [Mus musculus]" 15275 4156.19 106.86 106.9166667 0.000764842 Up 0.08525142 Hk1 hexokinase 1 K00844|1|0.0|1775|mmu:15275|hexokinase [EC:2.7.1.1] - - - gi|225735584|ref|NP_001139572.1|/0/hexokinase-1 isoform HK1 [Mus musculus] 234384 955 18.64666667 18.71 0.004891805 Up 0.08525142 Mpv17l2 MPV17 mitochondrial membrane protein-like 2 K13348|1|1e-117|424|mmu:234384|protein Mpv17 GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle - - gi|34147205|ref|NP_898993.1|/1.09023e-116/mpv17-like protein 2 [Mus musculus] 66626 3898 40.36333333 40.30333333 -0.002146158 Down 0.08525142 Cdip1 cell death inducing Trp53 target 1 K00510|1|1e-26|95.9|mmu:15369|heme oxygenase (biliverdin-producing) [EC:1.14.14.18] GO:0043231//intracellular membrane-bounded organelle - GO:0019221//cytokine-mediated signaling pathway;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0012502//induction of programmed cell death gi|31542001|ref|NP_079946.2|/3.40251e-75/cell death-inducing p53-target protein 1 [Mus musculus] 17188 2385 28.04666667 27.98333333 -0.003261493 Down 0.08525142 Maz MYC-associated zinc finger protein (purine-binding transcription factor) K17559|1|3e-68|262|chx:102182741|phostensin;K03252|2|8e-40|168|aam:106489419|translation initiation factor 3 subunit C;K09228|4|1e-30|137|obi:106879556|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle "GO:0046914//transition metal ion binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//transcription factor activity, sequence-specific DNA binding" GO:0006366//transcription from RNA polymerase II promoter "gi|119600409|gb|EAW80003.1|/1.67992e-137/MYC-associated zinc finger protein (purine-binding transcription factor), isoform CRA_i [Homo sapiens]" 216874 4604.56 27.07 27.13333333 0.003371406 Up 0.08525142 Camta2 calmodulin binding transcription activator 2 K15706|1|2e-11|75.1|cmy:102942880|E3 ubiquitin-protein ligase RNF167 [EC:2.3.2.27];K16743|2|6e-07|60.1|pale:102878272|abnormal spindle-like microcephaly-associated protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0019899//enzyme binding;GO:0019899//enzyme binding;GO:0019899//enzyme binding;GO:0019899//enzyme binding GO:0003299;GO:0006366//transcription from RNA polymerase II promoter;GO:0003299;GO:0006366//transcription from RNA polymerase II promoter;GO:0003299;GO:0006366//transcription from RNA polymerase II promoter;GO:0003299;GO:0006366//transcription from RNA polymerase II promoter "gi|148680657|gb|EDL12604.1|/0/calmodulin binding transcription activator 2, isoform CRA_b, partial [Mus musculus]" 16341 1541 44.48 44.54333333 0.002052736 Up 0.08525142 Eif3e "eukaryotic translation initiation factor 3, subunit E" K03250|1|0.0|903|myd:102765635|translation initiation factor 3 subunit E GO:0043234//protein complex;GO:0044427;GO:0016604//nuclear body;GO:0044444//cytoplasmic part "GO:0008135//translation factor activity, RNA binding;GO:0005515//protein binding" GO:0006413//translational initiation;GO:0000956//nuclear-transcribed mRNA catabolic process gi|987926417|ref|XP_006753964.2|/0/PREDICTED: eukaryotic translation initiation factor 3 subunit E [Myotis davidii] 67210 2547 43.12 43.06 -0.002008859 Down 0.08525142 Gatad1 GATA zinc finger domain containing 1 - GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity - gi|655837570|ref|XP_002713853.2|/6.9033e-111/PREDICTED: GATA zinc finger domain-containing protein 1 [Oryctolagus cuniculus] 56395 2177 15.94 15.99 0.004518309 Up 0.085025763 Tmem115 transmembrane protein 115 K04859|1|1e-94|350|clv:102096453|voltage-dependent calcium channel alpha-2/delta-2 - - - - 67105 1315 18.45 18.4 -0.00391505 Down 0.085025763 Timm21 tranlocase of inner mitochondrial membrane 21 K17796|1|2e-129|464|mmu:67105|mitochondrial import inner membrane translocase subunit TIM21 GO:0031224//intrinsic component of membrane;GO:0005743//mitochondrial inner membrane - GO:0010257//NADH dehydrogenase complex assembly;GO:0006626//protein targeting to mitochondrion;GO:0008535//respiratory chain complex IV assembly gi|21313128|ref|NP_080245.1|/1.55156e-128/mitochondrial import inner membrane translocase subunit Tim21 [Mus musculus] 102339 2754.64 31.47 31.42333333 -0.002140951 Down 0.085025763 Cog4 component of oligomeric golgi complex 4 K20291|1|0.0|1443|mmu:102339|conserved oligomeric Golgi complex subunit 4 GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle - GO:0048193//Golgi vesicle transport;GO:0045184//establishment of protein localization;GO:0043623//cellular protein complex assembly;GO:0006996//organelle organization "gi|148679526|gb|EDL11473.1|/0/component of oligomeric golgi complex 4, isoform CRA_a, partial [Mus musculus]" 67739 2526 42.45 42.50333333 0.001811436 Up 0.085025763 Slc48a1 "solute carrier family 48 (heme transporter), member 1" "K15380|1|3e-67|259|mmu:67739|solute carrier family 48 (heme transporter), member 1" GO:0000323//lytic vacuole;GO:0031090//organelle membrane;GO:0031224//intrinsic component of membrane GO:0051184 GO:0051181//cofactor transport gi|74219814|dbj|BAE40496.1|/1.43035e-100/unnamed protein product [Mus musculus] 58521 2559 14.61333333 14.56666667 -0.004614519 Down 0.085025763 Eid1 EP300 interacting inhibitor of differentiation 1 K17449|1|7e-10|68.9|myd:102762219|SHC-transforming protein 4 - - - - 98053 1720 20.86333333 20.81333333 -0.003461639 Down 0.085025763 Gtf2f1 "general transcription factor IIF, polypeptide 1" K03138|1|0.0|648|mmu:98053|transcription initiation factor TFIIF subunit alpha GO:0005667//transcription factor complex GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0008047//enzyme activator activity GO:0006366//transcription from RNA polymerase II promoter;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0051707//response to other organism;GO:0006397//mRNA processing;GO:0044764;GO:0044093;GO:0000377 gi|20270031|ref|NP_598562.1|/0/general transcription factor IIF subunit 1 [Mus musculus] 76524 2136 18.95333333 18.9 -0.004065364 Down 0.085025763 Cln6 "ceroid-lipofuscinosis, neuronal 6" K12359|1|5e-171|603|mmu:76524|ceroid-lipofuscinosis neuronal protein 6 GO:0031224//intrinsic component of membrane;GO:0044432;GO:0031090//organelle membrane GO:0042802//identical protein binding GO:0006022;GO:0050953//sensory perception of light stimulus;GO:0007626//locomotory behavior;GO:0006508//proteolysis;GO:0016125//sterol metabolic process;GO:0009057//macromolecule catabolic process;GO:0006672//ceramide metabolic process;GO:0035751//regulation of lysosomal lumen pH gi|75677520|ref|NP_001028347.1|/4.05601e-170/ceroid-lipofuscinosis neuronal protein 6 [Mus musculus] 21928 3590 19.80666667 19.76 -0.003403158 Down 0.085025763 Tnfaip2 "tumor necrosis factor, alpha-induced protein 2" K19989|1|0.0|1213|mmu:21928|tumor necrosis factor alpha-induced protein 2 - - GO:0048646//anatomical structure formation involved in morphogenesis;GO:0016192//vesicle-mediated transport;GO:0048869//cellular developmental process gi|194394239|ref|NP_033422.2|/0/tumor necrosis factor alpha-induced protein 2 [Mus musculus] 66192 760 17.86 17.80666667 -0.004314605 Down 0.085025763 Lage3 "L antigen family, member 3" K15902|1|1e-80|301|mmu:66192|EKC/KEOPS complex subunit PCC1/LAGE3 - - - gi|13384798|ref|NP_079686.1|/9.11659e-80/EKC/KEOPS complex subunit Lage3 [Mus musculus] 20163 1607 26.70333333 26.74 0.001979623 Up 0.084649667 Rsu1 Ras suppressor protein 1 K16175|1|1e-25|120|phu:Phum_PHUM127710|protein scribble - - - - 76479 2125 18.14 18.17666667 0.002913199 Up 0.084649667 Smndc1 survival motor neuron domain containing 1 K12839|1|3e-113|411|mmu:76479|survival of motor neuron-related-splicing factor 30 GO:0016604//nuclear body;GO:0030529//intracellular ribonucleoprotein complex GO:0003676//nucleic acid binding GO:0012502//induction of programmed cell death;GO:0008380//RNA splicing "gi|148669751|gb|EDL01698.1|/1.9584e-124/survival motor neuron domain containing 1, isoform CRA_b, partial [Mus musculus]" 56705 3064 19.82 19.78333333 -0.002671433 Down 0.084649667 Ranbp9 RAN binding protein 9 K13177|1|3e-09|67.0|loa:LOAG_08173|ATP-dependent RNA helicase DDX1 [EC:3.6.4.13];K12169|2|5e-09|66.2|aec:105154204|Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0044444//cytoplasmic part GO:0017016//Ras GTPase binding GO:0006935//chemotaxis;GO:0000226//microtubule cytoskeleton organization;GO:0065003 gi|62287487|sp|P69566.1|RANB9_MOUSE/0/RecName: Full=Ran-binding protein 9; Short=RanBP9; AltName: Full=B-cell antigen receptor Ig beta-associated protein 1; Short=IBAP-1; AltName: Full=Ran-binding protein M; Short=RanBPM 19651 4863.58 11.96333333 11.92666667 -0.004428536 Down 0.084649667 Rbl2 retinoblastoma-like 2 K16332|1|0.0|1997|mmu:19651|retinoblastoma-like protein 2 GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0019216//regulation of lipid metabolic process;GO:0051318;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization;GO:0019216//regulation of lipid metabolic process;GO:0051318;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization;GO:0019216//regulation of lipid metabolic process;GO:0051318;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization" gi|170932488|ref|NP_035380.3|/0/retinoblastoma-like protein 2 isoform 1 [Mus musculus] 74026 4358 23.76666667 23.73 -0.002227475 Down 0.084649667 Msl1 male-specific lethal 1 homolog (Drosophila) K13163|1|0.0|850|mmu:74026|male-specific lethal 1 - - - - 80288 5341 23.54 23.57666667 0.00224544 Up 0.084649667 Bcl9l B cell CLL/lymphoma 9-like K15157|1|3e-08|64.7|der:Dere_GG24724|mediator of RNA polymerase II transcription subunit 15;K03006|2|4e-08|64.3|rro:104669448|DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding GO:0006366//transcription from RNA polymerase II promoter;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0001837//epithelial to mesenchymal transition;GO:0019827//stem cell population maintenance;GO:0007519//skeletal muscle tissue development gi|564363348|ref|XP_006242986.1|/0/PREDICTED: B-cell CLL/lymphoma 9-like protein isoform X2 [Rattus norvegicus] 76233 1257 18.74666667 18.79 0.003330973 Up 0.084649667 Dnttip1 "deoxynucleotidyltransferase, terminal, interacting protein 1" K08707|1|1e-161|572|mmu:76233|deoxynucleotidyltransferase terminal-interacting protein 1 GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity;GO:0042802//identical protein binding;GO:0030234//enzyme regulator activity GO:0044093 gi|19526976|ref|NP_598524.1|/8.45658e-161/deoxynucleotidyltransferase terminal-interacting protein 1 [Mus musculus] 83485 1369.63 14.26666667 14.22666667 -0.00405062 Down 0.084649667 Ngrn "neugrin, neurite outgrowth associated" K16582|1|3e-10|69.3|cmy:102940882|tubulin polyglutamylase TTLL6/13 [EC:6.-.-.-] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0048731//system development;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0048869//cellular developmental process gi|254028156|ref|NP_113552.3|/1.90286e-150/neugrin precursor [Mus musculus] 228607 2989.83 46.28 46.24333333 -0.00114347 Down 0.084649667 Mavs mitochondrial antiviral signaling protein K12648|1|0.0|906|mmu:228607|mitochondrial antiviral-signaling protein GO:0031224//intrinsic component of membrane;GO:0044439;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0044439;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0044439;GO:0031966//mitochondrial membrane;GO:0031224//intrinsic component of membrane;GO:0044439;GO:0031966//mitochondrial membrane GO:0060089;GO:0019900//kinase binding;GO:0019904//protein domain specific binding;GO:0060089;GO:0019900//kinase binding;GO:0019904//protein domain specific binding;GO:0060089;GO:0019900//kinase binding;GO:0019904//protein domain specific binding;GO:0060089;GO:0019900//kinase binding;GO:0019904//protein domain specific binding "GO:0050691//regulation of defense response to virus by host;GO:0001932//regulation of protein phosphorylation;GO:0044093;GO:0032481//positive regulation of type I interferon production;GO:0019079//viral genome replication;GO:0043330//response to exogenous dsRNA;GO:0042307//positive regulation of protein import into nucleus;GO:0000060//protein import into nucleus, translocation;GO:0032722//positive regulation of chemokine production;GO:0006366//transcription from RNA polymerase II promoter;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0033043//regulation of organelle organization;GO:0039528//cytoplasmic pattern recognition receptor signaling pathway in response to virus;GO:0050691//regulation of defense response to virus by host;GO:0001932//regulation of protein phosphorylation;GO:0044093;GO:0032481//positive regulation of type I interferon production;GO:0019079//viral genome replication;GO:0043330//response to exogenous dsRNA;GO:0042307//positive regulation of protein import into nucleus;GO:0000060//protein import into nucleus, translocation;GO:0032722//positive regulation of chemokine production;GO:0006366//transcription from RNA polymerase II promoter;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0033043//regulation of organelle organization;GO:0039528//cytoplasmic pattern recognition receptor signaling pathway in response to virus;GO:0050691//regulation of defense response to virus by host;GO:0001932//regulation of protein phosphorylation;GO:0044093;GO:0032481//positive regulation of type I interferon production;GO:0019079//viral genome replication;GO:0043330//response to exogenous dsRNA;GO:0042307//positive regulation of protein import into nucleus;GO:0000060//protein import into nucleus, translocation;GO:0032722//positive regulation of chemokine production;GO:0006366//transcription from RNA polymerase II promoter;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0033043//regulation of organelle organization;GO:0039528//cytoplasmic pattern recognition receptor signaling pathway in response to virus;GO:0050691//regulation of defense response to virus by host;GO:0001932//regulation of protein phosphorylation;GO:0044093;GO:0032481//positive regulation of type I interferon production;GO:0019079//viral genome replication;GO:0043330//response to exogenous dsRNA;GO:0042307//positive regulation of protein import into nucleus;GO:0000060//protein import into nucleus, translocation;GO:0032722//positive regulation of chemokine production;GO:0006366//transcription from RNA polymerase II promoter;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0033043//regulation of organelle organization;GO:0039528//cytoplasmic pattern recognition receptor signaling pathway in response to virus" "gi|148696369|gb|EDL28316.1|/0/RIKEN cDNA D430028G21, isoform CRA_b, partial [Mus musculus]" 109264 4370 24.82666667 24.78666667 -0.002326303 Down 0.084649667 Me3 "malic enzyme 3, NADP(+)-dependent, mitochondrial" K00029|1|0.0|1193|mmu:109264|malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] GO:0044429 GO:0043169//cation binding;GO:0004470//malic enzyme activity;GO:0000166//nucleotide binding GO:0045333//cellular respiration;GO:0032787//monocarboxylic acid metabolic process;GO:0043648//dicarboxylic acid metabolic process "gi|225579045|ref|NP_852072.2|/0/NADP-dependent malic enzyme, mitochondrial [Mus musculus]" 76722 1516 1861.2 1861.24 3.10E-05 Up 0.084649667 Ckmt2 "creatine kinase, mitochondrial 2" K00933|1|0.0|857|rno:688698|creatine kinase [EC:2.7.3.2] GO:0043231//intracellular membrane-bounded organelle;GO:0030016//myofibril;GO:0019866//organelle inner membrane GO:0032550;GO:0016301//kinase activity GO:0006603//phosphocreatine metabolic process gi|537215227|gb|ERE81679.1|/0/creatine kinase S-type [Cricetulus griseus] 110960 2636 12.73666667 12.69333333 -0.004916779 Down 0.084649667 Tars threonyl-tRNA synthetase K01868|1|0.0|1437|mmu:110960|threonyl-tRNA synthetase [EC:6.1.1.3] - - - - 22680 2470.72 34.77666667 34.82 0.001796546 Up 0.084649667 Zfp207 zinc finger protein 207 - - - - "gi|148683690|gb|EDL15637.1|/6.29417e-63/zinc finger protein 207, isoform CRA_b, partial [Mus musculus]" 54485 3451 11.82 11.78333333 -0.004482321 Down 0.084649667 Dll4 delta-like 4 (Drosophila) K06051|1|0.0|1426|mmu:54485|delta GO:0016021//integral component of membrane GO:0046872//metal ion binding;GO:0005102//receptor binding GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0001525//angiogenesis;GO:0010596//negative regulation of endothelial cell migration;GO:0022008//neurogenesis;GO:0048771//tissue remodeling;GO:0002011//morphogenesis of an epithelial sheet;GO:0007219//Notch signaling pathway;GO:0035907//dorsal aorta development gi|244799228|ref|NP_062327.2|/0/delta-like protein 4 precursor [Mus musculus] 228983 2745 22.52 22.48 -0.002564792 Down 0.084649667 Osbpl2 oxysterol binding protein-like 2 K20174|1|0.0|901|mmu:228983|oxysterol-binding protein-related protein 1/2 - GO:0032934//sterol binding GO:0051234//establishment of localization;GO:0010876//lipid localization gi|110625879|ref|NP_653083.2|/0/oxysterol-binding protein-related protein 2 [Mus musculus] 51788 1069 20.97333333 21.00333333 0.002062139 Up 0.08418895 H2afz "H2A histone family, member Z" K11251|1|9e-38|159|gja:107114477|histone H2A - - - - 142688 2280.81 7.843333333 7.816666667 -0.004913398 Down 0.08418895 Asb13 ankyrin repeat and SOCS box-containing 13 K10335|1|2e-149|532|mmu:142688|ankyrin repeat and SOCS box protein 13 - GO:0005488//binding GO:0007165//signal transduction;GO:0032446//protein modification by small protein conjugation;GO:0007165//signal transduction gi|850311636|ref|XP_012862695.1|/6.2734e-35/PREDICTED: ankyrin repeat and SOCS box protein 13 [Echinops telfairi] 19165 2017 10.56333333 10.59 0.00363743 Up 0.08418895 Psen2 presenilin 2 K04522|1|0.0|768|mmu:19165|presenilin 2 [EC:3.4.23.-] - - - gi|190684661|ref|NP_035313.2|/0/presenilin-2 [Mus musculus] 67515 1832 12.93666667 12.90666667 -0.003349481 Down 0.08418895 Ttc33 tetratricopeptide repeat domain 33 K02433|1|2e-14|83.2|tsp:Tsp_08794|aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7];K09560|2|4e-07|59.3|soc:105198105|suppressor of tumorigenicity protein 13;K16365|4|2e-06|56.6|aga:AgaP_AGAP003052|small glutamine-rich tetratricopeptide repeat-containing protein alpha - - - gi|21312920|ref|NP_080489.1|/1.57464e-135/tetratricopeptide repeat protein 33 [Mus musculus] 67892 780 11.21666667 11.24333333 0.003425814 Up 0.08418895 Coa6 cytochrome c oxidase assembly factor 6 K18179|1|2e-46|187|rno:102556031|cytochrome c oxidase assembly factor 6 GO:0043231//intracellular membrane-bounded organelle GO:0015002//heme-copper terminal oxidase activity - gi|564321710|ref|XP_002725487.2|/1.5416e-45/PREDICTED: uncharacterized protein LOC102556031 isoform X1 [Rattus norvegicus] 17965 1762 14.9 14.87333333 -0.002584318 Down 0.08418895 Nbl1 "neuroblastoma, suppression of tumorigenicity 1" K19558|1|6e-70|267|chx:102168874|neuroblastoma suppressor of tumorigenicity 1 - GO:0019955//cytokine binding GO:0030514//negative regulation of BMP signaling pathway;GO:0002689//negative regulation of leukocyte chemotaxis;GO:0031175//neuron projection development;GO:0009953//dorsal/ventral pattern formation gi|926686539|ref|XP_013830169.1|/5.42136e-69/PREDICTED: neuroblastoma suppressor of tumorigenicity 1 [Capra hircus] 66922 2289 16.32333333 16.35333333 0.002649038 Up 0.08418895 Rras2 related RAS viral (r-ras) oncogene 2 K07830|1|3e-107|392|chx:102190712|Ras-related protein R-Ras2 GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0016477//cell migration;GO:0009154//purine ribonucleotide catabolic process;GO:0007264//small GTPase mediated signal transduction gi|21361416|ref|NP_036382.2|/2.6426e-106/ras-related protein R-Ras2 isoform a [Homo sapiens] 80907 2031 9.936666667 9.906666667 -0.004362259 Down 0.08418895 Lactb "lactamase, beta" "K17382|1|0.0|973|mmu:80907|serine beta-lactamase-like protein LACTB, mitochondrial" GO:0043231//intracellular membrane-bounded organelle GO:0003824//catalytic activity - "gi|13507666|ref|NP_109642.1|/0/serine beta-lactamase-like protein LACTB, mitochondrial precursor [Mus musculus]" 19294 2109.16 24.01666667 24.04333333 0.001600993 Up 0.08418895 Pvrl2 nectin cell adhesion molecule 2 K06531|1|0.0|866|mmu:19294|poliovirus receptor-related protein 2 GO:0005913//cell-cell adherens junction;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0005913//cell-cell adherens junction;GO:0044464;GO:0031224//intrinsic component of membrane GO:0042802//identical protein binding;GO:0042802//identical protein binding GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0046718//viral entry into host cell;GO:0032989;GO:0051646//mitochondrion localization;GO:0016337//single organismal cell-cell adhesion;GO:0002420;GO:0019062//virion attachment to host cell;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0002696//positive regulation of leukocyte activation;GO:0030030//cell projection organization;GO:0006997//nucleus organization;GO:0007281//germ cell development;GO:0002714;GO:0007005//mitochondrion organization;GO:0051702//interaction with symbiont;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0046718//viral entry into host cell;GO:0032989;GO:0051646//mitochondrion localization;GO:0016337//single organismal cell-cell adhesion;GO:0002420;GO:0019062//virion attachment to host cell;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0002696//positive regulation of leukocyte activation;GO:0030030//cell projection organization;GO:0006997//nucleus organization;GO:0007281//germ cell development;GO:0002714;GO:0007005//mitochondrion organization;GO:0051702//interaction with symbiont gi|228480275|ref|NP_001153196.1|/0/nectin-2 isoform 2 precursor [Mus musculus] 192174 2971 14.13333333 14.16333333 0.003059079 Up 0.08418895 Rwdd4a RWD domain containing 4A - - - - - 76608 4582 10.03666667 10.00333333 -0.004799389 Down 0.08418895 Hectd3 HECT domain containing 3 K12233|1|0.0|1666|mmu:76608|E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26] GO:0044444//cytoplasmic part GO:0000149//SNARE binding;GO:0019787//ubiquitin-like protein transferase activity GO:0036211//protein modification process;GO:0006511//ubiquitin-dependent protein catabolic process "gi|148698628|gb|EDL30575.1|/0/HECT domain containing 3, isoform CRA_b, partial [Mus musculus]" 66251 2618 7.786666667 7.76 -0.004949216 Down 0.08418895 Arfgap3 ADP-ribosylation factor GTPase activating protein 3 K12493|1|0.0|961|mmu:66251|ADP-ribosylation factor GTPase-activating protein 2/3 GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0046914//transition metal ion binding GO:0015031//protein transport;GO:0032012//regulation of ARF protein signal transduction gi|30841021|ref|NP_079721.2|/0/ADP-ribosylation factor GTPase-activating protein 3 [Mus musculus] 68048 2504 17.00333333 17.03 0.002260835 Up 0.08418895 Aen apoptosis enhancing nuclease K18340|1|2e-174|615|mmu:68048|apoptosis-enhancing nuclease [EC:3.1.-.-] GO:0031981//nuclear lumen;GO:0031981//nuclear lumen GO:0004518//nuclease activity;GO:0097159//organic cyclic compound binding;GO:0004518//nuclease activity;GO:0097159//organic cyclic compound binding GO:0009314//response to radiation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0009314//response to radiation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage gi|26327783|dbj|BAC27632.1|/0/unnamed protein product [Mus musculus] 214742 3213.78 10.16333333 10.19 0.003780402 Up 0.08418895 Rcor3 REST corepressor 3 K11829|1|2e-141|505|gga:428911|REST corepressor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|590122011|ref|NP_659063.3|/0/REST corepressor 3 isoform a [Mus musculus] 101540 3476.02 13.88 13.91333333 0.003460532 Up 0.08418895 Prkd2 protein kinase D2 K06070|1|0.0|1580|mmu:101540|protein kinase D [EC:2.7.11.13] GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0004674//protein serine/threonine kinase activity;GO:0008289//lipid binding;GO:0032550;GO:0043169//cation binding;GO:0004674//protein serine/threonine kinase activity;GO:0008289//lipid binding;GO:0032550;GO:0043169//cation binding GO:0001935//endothelial cell proliferation;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010595//positive regulation of endothelial cell migration;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0043410//positive regulation of MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0001819//positive regulation of cytokine production;GO:0003159;GO:0050852//T cell receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0007155//cell adhesion;GO:0001525//angiogenesis;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0038089//positive regulation of cell migration by vascular endothelial growth factor signaling pathway;GO:0090045//positive regulation of deacetylase activity;GO:0001935//endothelial cell proliferation;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0010595//positive regulation of endothelial cell migration;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0043410//positive regulation of MAPK cascade;GO:0001934//positive regulation of protein phosphorylation;GO:0001819//positive regulation of cytokine production;GO:0003159;GO:0050852//T cell receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0007155//cell adhesion;GO:0001525//angiogenesis;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0038089//positive regulation of cell migration by vascular endothelial growth factor signaling pathway;GO:0090045//positive regulation of deacetylase activity "gi|148710129|gb|EDL42075.1|/0/protein kinase D2, isoform CRA_a, partial [Mus musculus]" 170728 2981 31.62333333 31.59666667 -0.001217079 Down 0.08418895 Rtn4ip1 reticulon 4 interacting protein 1 K00344|1|1e-19|101|myd:102760205|NADPH2:quinone reductase [EC:1.6.5.5] - - - "gi|31543608|ref|NP_570962.2|/0/reticulon-4-interacting protein 1, mitochondrial precursor [Mus musculus]" 69957 2253 14.1 14.07 -0.003072834 Down 0.08418895 Cdc16 CDC16 cell division cycle 16 K03353|1|0.0|1271|mmu:69957|anaphase-promoting complex subunit 6 GO:0005815//microtubule organizing center;GO:0000152//nuclear ubiquitin ligase complex;GO:0005819//spindle - GO:0000209//protein polyubiquitination;GO:0000087//mitotic M phase gi|68448515|ref|NP_081552.2|/0/cell division cycle protein 16 homolog [Mus musculus] 68115 1325 17.77666667 17.74666667 -0.002436757 Down 0.08418895 9430016H08Rik RIKEN cDNA 9430016H08 gene - GO:0043231//intracellular membrane-bounded organelle - - "gi|148667637|gb|EDL00054.1|/1.73895e-127/mCG113908, partial [Mus musculus]" 69257 5679.59 11.09 11.11666667 0.003464895 Up 0.08418895 Elf2 E74-like factor 2 K09428|1|0.0|995|mmu:69257|E74-like factor 1/2/4 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter gi|597517979|ref|NP_001277991.1|/0/ETS-related transcription factor Elf-2 isoform 3 [Mus musculus] 319760 2844.54 1.563333333 1.57 0.006139137 Up 0.084010305 D130020L05Rik RIKEN cDNA D130020L05 gene K17491|1|2e-19|100|xtr:100485426|protein phosphatase 4 regulatory subunit 3 - - - gi|26327485|dbj|BAC27486.1|/4.04791e-84/unnamed protein product [Mus musculus] 279653 10165 0.776666667 0.783333333 0.012330802 Up 0.084010305 Pcdh19 protocadherin 19 K16499|1|0.0|2067|mmu:279653|protocadherin delta 2 GO:0016020//membrane GO:0046872//metal ion binding GO:0016337//single organismal cell-cell adhesion gi|157426849|ref|NP_001098715.1|/0/protocadherin-19 isoform a precursor [Mus musculus] 117606 4428 2.436666667 2.426666667 -0.005932956 Down 0.084010305 Boc biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein K20020|1|0.0|2127|mmu:117606|brother of CDO GO:0044297//cell body;GO:0030426//growth cone - GO:0006935//chemotaxis;GO:0007166//cell surface receptor signaling pathway;GO:0045445//myoblast differentiation;GO:0016043//cellular component organization gi|27777681|ref|NP_766094.1|/0/brother of CDO precursor [Mus musculus] 434350 2548 0.796666667 0.79 -0.012123559 Down 0.084010305 9430091E24Rik RIKEN cDNA 9430091E24 gene K17509|1|8e-11|72.0|pon:100458247|pyruvate dehydrogenase phosphatase regulatory subunit - - - - 22709 2578 1.563333333 1.553333333 -0.009257968 Down 0.084010305 Zfp51 zinc finger protein 51 K09228|1|0.0|1666|mmu:22709|KRAB domain-containing zinc finger protein - - - gi|124269710|ref|NP_033584.3|/0/zinc finger protein 51 [Mus musculus] 74386 3580.2 2.376666667 2.366666667 -0.006083052 Down 0.084010305 Rmi1 RecQ mediated genome instability 1 K10990|1|0.0|1165|mmu:74386|RecQ-mediated genome instability protein 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle - GO:0006259//DNA metabolic process;GO:0006259//DNA metabolic process;GO:0006259//DNA metabolic process gi|270265788|ref|NP_083180.3|/0/recQ-mediated genome instability protein 1 [Mus musculus] 216965 12411 3.333333333 3.32 -0.005782353 Down 0.084010305 Taok1 TAO kinase 1 K04429|1|0.0|1827|mmu:216965|thousand and one amino acid protein kinase [EC:2.7.11.1] GO:0044424 GO:0032550;GO:0004672//protein kinase activity;GO:0019887//protein kinase regulator activity;GO:0019900//kinase binding GO:0001934//positive regulation of protein phosphorylation;GO:0032872//regulation of stress-activated MAPK cascade;GO:0007010//cytoskeleton organization;GO:0012501//programmed cell death;GO:0006259//DNA metabolic process;GO:0007254//JNK cascade;GO:0000077//DNA damage checkpoint gi|124358959|ref|NP_659074.2|/0/serine/threonine-protein kinase TAO1 [Mus musculus] 100502700 733 1.453333333 1.466666667 0.013175389 Up 0.084010305 AV039307 expressed sequence AV039307 K10625|1|1e-29|131|mmu:22222|E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27] - - - gi|12838906|dbj|BAB24370.1|/2.60603e-55/unnamed protein product [Mus musculus] 78908 7330 2.1 2.11 0.006853671 Up 0.084010305 Igsf3 "immunoglobulin superfamily, member 3" "K06522|1|0.0|2327|mmu:78908|immunoglobulin superfamily, member 2/3" GO:0031224//intrinsic component of membrane - - gi|37359966|dbj|BAC97961.1|/0/mKIAA0466 protein [Mus musculus] 19099 3120.91 2.763333333 2.776666667 0.006944394 Up 0.084010305 Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 K04434|1|0.0|1186|mmu:19099|mitogen-activated protein kinase 8 interacting protein 1 GO:0030426//growth cone;GO:0031090//organelle membrane;GO:0030424//axon;GO:0005740//mitochondrial envelope;GO:0030426//growth cone;GO:0031090//organelle membrane;GO:0030424//axon;GO:0005740//mitochondrial envelope;GO:0030426//growth cone;GO:0031090//organelle membrane;GO:0030424//axon;GO:0005740//mitochondrial envelope "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0032947//protein complex scaffold;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0032947//protein complex scaffold;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0019901//protein kinase binding;GO:0008092//cytoskeletal protein binding;GO:0032947//protein complex scaffold" "GO:0006351//transcription, DNA-templated;GO:0006810//transport;GO:0043407//negative regulation of MAP kinase activity;GO:0006915//apoptotic process;GO:0007254//JNK cascade;GO:0006351//transcription, DNA-templated;GO:0006810//transport;GO:0043407//negative regulation of MAP kinase activity;GO:0006915//apoptotic process;GO:0007254//JNK cascade;GO:0006351//transcription, DNA-templated;GO:0006810//transport;GO:0043407//negative regulation of MAP kinase activity;GO:0006915//apoptotic process;GO:0007254//JNK cascade" gi|320461744|ref|NP_001189374.1|/0/C-Jun-amino-terminal kinase-interacting protein 1 isoform 2 [Mus musculus] 226098 4774 0.706666667 0.7 -0.013674937 Down 0.084010305 Hectd2 HECT domain containing 2 K12232|1|0.0|1374|mmu:226098|E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26] GO:0044464;GO:0044464 GO:0019787//ubiquitin-like protein transferase activity;GO:0019787//ubiquitin-like protein transferase activity GO:0032446//protein modification by small protein conjugation;GO:0032446//protein modification by small protein conjugation gi|254939513|ref|NP_766225.2|/0/probable E3 ubiquitin-protein ligase HECTD2 isoform 2 [Mus musculus] 66926 2820 3.613333333 3.6 -0.005333444 Down 0.084010305 Trmt6 tRNA methyltransferase 6 K03256|1|0.0|877|mmu:66926|tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit GO:0043231//intracellular membrane-bounded organelle "GO:0016741;GO:0008135//translation factor activity, RNA binding" GO:0006413//translational initiation;GO:0006399//tRNA metabolic process gi|37360264|dbj|BAC98110.1|/0/mKIAA1153 protein [Mus musculus] 74352 5711 1.716666667 1.73 0.011162106 Up 0.084010305 Zfp84 zinc finger protein 84 K09228|1|0.0|1196|mmu:74352|KRAB domain-containing zinc finger protein - - - gi|29789231|ref|NP_076239.1|/0/zinc finger protein 84 [Mus musculus] 17156 7960 2.263333333 2.273333333 0.006360165 Up 0.084010305 Man1a2 "mannosidase, alpha, class 1A, member 2" "K01230|1|0.0|1150|mmu:17156|mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]" GO:0031224//intrinsic component of membrane;GO:0031981//nuclear lumen;GO:0012505//endomembrane system GO:0046872//metal ion binding;GO:0015924//mannosyl-oligosaccharide mannosidase activity GO:0030324//lung development;GO:0006487//protein N-linked glycosylation "gi|6754620|ref|NP_034893.1|/0/mannosyl-oligosaccharide 1,2-alpha-mannosidase IB [Mus musculus]" 20911 2703 2.633333333 2.643333333 0.005468213 Up 0.084010305 Stxbp2 syntaxin binding protein 2 K15300|1|0.0|1101|mmu:20911|syntaxin-binding protein 2 GO:0030141//secretory granule;GO:0043234//protein complex;GO:0044459;GO:0005766;GO:0031252//cell leading edge GO:0019905//syntaxin binding GO:0002886;GO:0001906//cell killing;GO:0002283//neutrophil activation involved in immune response;GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0009268//response to pH gi|6755688|ref|NP_035633.1|/0/syntaxin-binding protein 2 [Mus musculus] 68146 3541 2.303333333 2.313333333 0.006249952 Up 0.084010305 Arl13b ADP-ribosylation factor-like 13B K07962|1|0.0|657|mmu:68146|ADP-ribosylation factor-like protein 13B GO:0043231//intracellular membrane-bounded organelle GO:0032550 GO:0003002//regionalization;GO:0035556//intracellular signal transduction;GO:0009855//determination of bilateral symmetry gi|255683326|ref|NP_080853.3|/0/ADP-ribosylation factor-like protein 13B [Mus musculus] 72391 773 0.813333333 0.82 0.011777168 Up 0.084010305 Cdkn3 cyclin-dependent kinase inhibitor 3 K14167|1|3e-106|386|mmu:72391|cyclin-dependent kinase inhibitor 3 [EC:3.1.3.16 3.1.3.48] GO:0044444//cytoplasmic part GO:0005488//binding;GO:0004721//phosphoprotein phosphatase activity GO:0006470//protein dephosphorylation;GO:0022402//cell cycle process "gi|148688772|gb|EDL20719.1|/2.51723e-109/mCG4635, isoform CRA_c, partial [Mus musculus]" 108829 8442.04 2.026666667 2.013333333 -0.009522774 Down 0.084010305 Jmjd1c jumonji domain containing 1C K11449|1|0.0|4256|rno:171120|jumonji domain-containing protein 1C [EC:1.14.11.-] - - - gi|226531205|ref|NP_997104.2|/0/probable JmjC domain-containing histone demethylation protein 2C isoform 1 [Mus musculus] 26757 2646 2.74 2.753333333 0.007003388 Up 0.084010305 Dpysl4 dihydropyrimidinase-like 4 K07528|1|0.0|895|amj:106736762|dihydropyrimidinase-like 2 GO:0044424 "GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0005515//protein binding" GO:0030182//neuron differentiation;GO:0006206//pyrimidine nucleobase metabolic process gi|188219524|ref|NP_036123.3|/0/dihydropyrimidinase-related protein 4 [Mus musculus] 71306 6223.22 0.963333333 0.97 0.00994966 Up 0.084010305 Mfap3l microfibrillar-associated protein 3-like K06756|1|4e-06|57.8|api:100168201|neuronal cell adhesion molecule GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - "gi|148696688|gb|EDL28635.1|/3.18826e-152/microfibrillar-associated protein 3-like, isoform CRA_a, partial [Mus musculus]" 14726 1800 2.206666667 2.193333333 -0.008743633 Down 0.084010305 Pdpn podoplanin K16778|1|1e-67|259|mmu:14726|podoplanin GO:0031252//cell leading edge;GO:0042995//cell projection;GO:0044459;GO:0031252//cell leading edge;GO:0031224//intrinsic component of membrane;GO:0042995//cell projection;GO:0044459 GO:0005372//water transmembrane transporter activity;GO:0046943//carboxylic acid transmembrane transporter activity;GO:0051183//vitamin transporter activity;GO:0005372//water transmembrane transporter activity;GO:0046943//carboxylic acid transmembrane transporter activity;GO:0051183//vitamin transporter activity GO:0030324//lung development;GO:0010543//regulation of platelet activation;GO:0007155//cell adhesion;GO:0006835//dicarboxylic acid transport;GO:0006692;GO:0000902//cell morphogenesis;GO:0007154//cell communication;GO:0006952//defense response;GO:0016477//cell migration;GO:0042044//fluid transport;GO:0030324//lung development;GO:0022604//regulation of cell morphogenesis;GO:0010543//regulation of platelet activation;GO:0007155//cell adhesion;GO:0006835//dicarboxylic acid transport;GO:0006692;GO:0007154//cell communication;GO:0006952//defense response;GO:0016477//cell migration;GO:0042044//fluid transport gi|200165|gb|AAA39866.1|/1.06077e-62/OTS-8 [Mus musculus] 108943 3935 0.753333333 0.746666667 -0.01282404 Down 0.084010305 Trmt10a tRNA methyltransferase 10A K15445|1|7e-163|577|mmu:108943|tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221] - GO:0016741 GO:0008152//metabolic process gi|568921466|ref|XP_006500905.1|/4.38115e-163/PREDICTED: tRNA methyltransferase 10 homolog A isoform X2 [Mus musculus] 12667 3292 1.46 1.47 0.009847786 Up 0.084010305 Chrd chordin K04657|1|0.0|1744|mmu:12667|chordin GO:0044421;GO:0044421 GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding;GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding GO:0001649//osteoblast differentiation;GO:0007155//cell adhesion;GO:0021914//negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning;GO:0008284//positive regulation of cell proliferation;GO:0007420//brain development;GO:0030509//BMP signaling pathway;GO:0016477//cell migration;GO:0001704//formation of primary germ layer;GO:0001649//osteoblast differentiation;GO:0007155//cell adhesion;GO:0021914//negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning;GO:0008284//positive regulation of cell proliferation;GO:0007420//brain development;GO:0030509//BMP signaling pathway;GO:0016477//cell migration;GO:0001704//formation of primary germ layer gi|6753418|ref|NP_034023.1|/0/chordin isoform 1 precursor [Mus musculus] 56380 3807 1.236666667 1.246666667 0.011619083 Up 0.084010305 Arid3b AT rich interactive domain 3B (BRIGHT-like) K14829|1|2e-60|237|clv:102091091|pre-rRNA-processing protein IPI3;K11653|4|8e-21|105|crg:105347668|AT-rich interactive domain-containing protein 1 GO:0043231//intracellular membrane-bounded organelle - "GO:0006351//transcription, DNA-templated;GO:0032502//developmental process" gi|9790033|ref|NP_062663.1|/0/AT-rich interactive domain-containing protein 3B [Mus musculus] 22160 1665 0.743333333 0.736666667 -0.012997341 Down 0.084010305 Twist1 twist basic helix-loop-helix transcription factor 1 K09069|1|3e-51|205|mmu:22160|twist - - - - 242083 3962 3.7 3.713333333 0.005189556 Up 0.084010305 Ppm1l protein phosphatase 1 (formerly 2C)-like K17506|1|0.0|720|mmu:242083|protein phosphatase 1L [EC:3.1.3.16] GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane GO:0043169//cation binding;GO:0004721//phosphoprotein phosphatase activity GO:0007167//enzyme linked receptor protein signaling pathway;GO:0006464//cellular protein modification process;GO:0006665//sphingolipid metabolic process;GO:0006796//phosphate-containing compound metabolic process gi|66392585|ref|NP_848841.2|/0/protein phosphatase 1L [Mus musculus] 667250 978 1.513333333 1.5 -0.012767296 Down 0.084010305 Gm12657 predicted gene 12657 K11253|1|1e-71|272|cge:100761813|histone H3 - - - - 12297 2709.21 2.696666667 2.71 0.00711565 Up 0.084010305 Cacnb3 "calcium channel, voltage-dependent, beta 3 subunit" K04864|1|0.0|905|mmu:12297|voltage-dependent calcium channel beta-3 GO:0034704//calcium channel complex;GO:0044459;GO:0044444//cytoplasmic part;GO:0034704//calcium channel complex;GO:0044459;GO:0034704//calcium channel complex GO:0005245//voltage-gated calcium channel activity;GO:0019900//kinase binding;GO:0019900//kinase binding;GO:0005245//voltage-gated calcium channel activity GO:0007267//cell-cell signaling;GO:0006816//calcium ion transport;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006935//chemotaxis;GO:0034220//ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006816//calcium ion transport;GO:0050851//antigen receptor-mediated signaling pathway;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport gi|555943815|ref|NP_001273155.1|/0/voltage-dependent L-type calcium channel subunit beta-3 isoform 3 [Mus musculus] 77810 799 1.77 1.776666667 0.005423672 Up 0.084010305 A930015D03Rik RIKEN cDNA A930015D03 gene K02991|1|7e-14|61.2|nle:105738245|small subunit ribosomal protein S6e - - - - 100504262 1661 0.763333333 0.756666667 -0.012655301 Down 0.084010305 A730020E08Rik RIKEN cDNA A730020E08 gene - - - - "gi|68062078|ref|XP_673041.1|/1.75621e-13/hypothetical protein [Plasmodium berghei strain ANKA], partial [Plasmodium berghei ANKA]" 140484 5618 3.443333333 3.43 -0.005597272 Down 0.084010305 Pofut1 protein O-fucosyltransferase 1 K03691|1|0.0|781|mmu:140484|peptide-O-fucosyltransferase [EC:2.4.1.221] GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane GO:0008417//fucosyltransferase activity "GO:0048731//system development;GO:0019318//hexose metabolic process;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0044767//single-organism developmental process;GO:0007166//cell surface receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006493//protein O-linked glycosylation" gi|84794593|ref|NP_536711.3|/0/GDP-fucose protein O-fucosyltransferase 1 precursor [Mus musculus] 11303 10260 2.21 2.196666667 -0.008730405 Down 0.084010305 Abca1 "ATP-binding cassette, sub-family A (ABC1), member 1" "K05641|1|0.0|4380|mmu:11303|ATP-binding cassette, subfamily A (ABC1), member 1" GO:0030139//endocytic vesicle;GO:0034358//plasma lipoprotein particle;GO:0016021//integral component of membrane GO:0015405;GO:0000149//SNARE binding;GO:0015075//ion transmembrane transporter activity;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0004888//transmembrane signaling receptor activity;GO:0034185//apolipoprotein binding;GO:0015248//sterol transporter activity;GO:0051020//GTPase binding GO:0007033//vacuole organization;GO:0033363//secretory granule organization;GO:0032611//interleukin-1 beta production;GO:0015914//phospholipid transport;GO:0055092//sterol homeostasis;GO:0016125//sterol metabolic process;GO:0055094//response to lipoprotein particle;GO:0046903//secretion;GO:0034377//plasma lipoprotein particle assembly;GO:0034645//cellular macromolecule biosynthetic process;GO:0007166//cell surface receptor signaling pathway;GO:0032488//Cdc42 protein signal transduction;GO:0006464//cellular protein modification process;GO:0010874//regulation of cholesterol efflux;GO:0006171//cAMP biosynthetic process;GO:0032526//response to retinoic acid;GO:0032496//response to lipopolysaccharide;GO:0006909//phagocytosis gi|90568038|ref|NP_038482.3|/0/ATP-binding cassette sub-family A member 1 [Mus musculus] 319613 3054 1.813333333 1.8 -0.010647244 Down 0.084010305 Sybu syntabulin (syntaxin-interacting) K02599|1|3e-129|465|chx:102177020|Notch - - - - 207806 12622 1.476666667 1.486666667 0.009737011 Up 0.084010305 Usf3 upstream transcription factor family member 3 K10955|1|4e-09|68.9|asn:102388355|intestinal mucin-2;K17452|4|6e-07|61.6|mde:101896765|zinc finger protein AEBP2;K09106|5|1e-06|60.5|hst:105190845|upstream stimulatory factor - - - - 207375 7709 1.796666667 1.783333333 -0.010746381 Down 0.084010305 Fam120c "family with sequence similarity 120, member C" K08845|1|2e-12|79.3|gja:107120717|A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] - - - gi|126723307|ref|NP_932773.2|/0/constitutive coactivator of PPAR-gamma-like protein 2 [Mus musculus] 74568 2007 2.583333333 2.596666667 0.007427018 Up 0.084010305 Mlkl mixed lineage kinase domain-like K08849|1|0.0|907|mmu:74568|mixed lineage kinase domain-like [EC:2.7.11.1] - GO:0016740//transferase activity;GO:0032550;GO:0016740//transferase activity;GO:0032550 GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process "gi|544191853|pdb|4BTF|A/0/Chain A, Structure Of Mlkl" 56297 1512 2.206666667 2.22 0.00869096 Up 0.084010305 Arl6 ADP-ribosylation factor-like 6 K07951|1|8e-93|343|mmu:56297|ADP-ribosylation factor-like protein 6 GO:0043232;GO:0016020//membrane GO:0043169//cation binding;GO:0032550 GO:0007264//small GTPase mediated signal transduction;GO:0010927;GO:0007166//cell surface receptor signaling pathway;GO:0006486//protein glycosylation "gi|431892469|gb|ELK02907.1|/1.67276e-92/Ephrin type-A receptor 6, partial [Pteropus alecto]" 218613 5277 1.326666667 1.34 0.014427071 Up 0.084010305 Mier3 MIER family member 3 K11660|1|1e-14|85.9|cin:778679|metastasis-associated protein MTA GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|156231044|ref|NP_766181.2|/0/mesoderm induction early response protein 3 [Mus musculus] 16194 3374 2.323333333 2.333333333 0.006196266 Up 0.084010305 Il6ra "interleukin 6 receptor, alpha" K05055|1|0.0|830|mmu:16194|interleukin 6 receptor GO:0043025//neuronal cell body;GO:0044421;GO:0005887//integral component of plasma membrane;GO:0043025//neuronal cell body;GO:0044421;GO:0005887//integral component of plasma membrane GO:0019838//growth factor binding;GO:0005126//cytokine receptor binding;GO:0004896//cytokine receptor activity;GO:0042802//identical protein binding;GO:0019955//cytokine binding;GO:0019838//growth factor binding;GO:0005126//cytokine receptor binding;GO:0004896//cytokine receptor activity;GO:0042802//identical protein binding;GO:0019955//cytokine binding GO:0031016//pancreas development;GO:0040007//growth;GO:0010533;GO:0001818//negative regulation of cytokine production;GO:0010558;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0046683//response to organophosphorus;GO:0042742//defense response to bacterium;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0006915//apoptotic process;GO:0019221//cytokine-mediated signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0008284//positive regulation of cell proliferation;GO:0000165//MAPK cascade;GO:0097305//response to alcohol;GO:0031960//response to corticosteroid;GO:0010212//response to ionizing radiation;GO:0002237//response to molecule of bacterial origin;GO:0031016//pancreas development;GO:0040007//growth;GO:0010533;GO:0001818//negative regulation of cytokine production;GO:0010558;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0046683//response to organophosphorus;GO:0042742//defense response to bacterium;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0006915//apoptotic process;GO:0019221//cytokine-mediated signaling pathway;GO:0001819//positive regulation of cytokine production;GO:0008284//positive regulation of cell proliferation;GO:0000165//MAPK cascade;GO:0097305//response to alcohol;GO:0031960//response to corticosteroid;GO:0010212//response to ionizing radiation;GO:0002237//response to molecule of bacterial origin gi|893567041|ref|NP_001297605.1|/0/interleukin-6 receptor subunit alpha isoform 2 precursor [Mus musculus] 277360 6530 2.063333333 2.053333333 -0.007009059 Down 0.084010305 Prex1 "phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1" "K12365|1|0.0|3088|mmu:277360|phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein" - - - "gi|124517734|ref|NP_808450.2|/0/phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein [Mus musculus]" 80905 2580 2.483333333 2.493333333 0.005797845 Up 0.084010305 Polh "polymerase (DNA directed), eta (RAD 30 related)" K03509|1|0.0|1201|mmu:80905|DNA polymerase eta [EC:2.7.7.7] GO:0031981//nuclear lumen GO:0043169//cation binding;GO:0003677//DNA binding;GO:0034061//DNA polymerase activity GO:0009411//response to UV;GO:0006281//DNA repair gi|17105328|ref|NP_109640.1|/0/DNA polymerase eta [Mus musculus] 103468 3092 2.863333333 2.873333333 0.005029738 Up 0.084010305 Nup107 nucleoporin 107 K14301|1|0.0|1794|mmu:103468|nuclear pore complex protein Nup107 GO:0031981//nuclear lumen;GO:0005643//nuclear pore;GO:0000776//kinetochore GO:0005215//transporter activity;GO:0005198//structural molecule activity GO:0006999//nuclear pore organization;GO:0045184//establishment of protein localization;GO:0006405//RNA export from nucleus gi|29789351|ref|NP_598771.1|/0/nuclear pore complex protein Nup107 [Mus musculus] 14025 3098.34 0.993333333 1 0.00965017 Up 0.084010305 Bcl11a B cell CLL/lymphoma 11A (zinc finger protein) K09228|1|3e-11|73.9|lve:103085761|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0044451;GO:0044451;GO:0044451 GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity;GO:0046983//protein dimerization activity;GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity;GO:0046983//protein dimerization activity "GO:0030307//positive regulation of cell growth;GO:0006366//transcription from RNA polymerase II promoter;GO:0032460//negative regulation of protein oligomerization;GO:0030308//negative regulation of cell growth;GO:0032446//protein modification by small protein conjugation;GO:0010977//negative regulation of neuron projection development;GO:0030098//lymphocyte differentiation;GO:0030307//positive regulation of cell growth;GO:0006366//transcription from RNA polymerase II promoter;GO:0032460//negative regulation of protein oligomerization;GO:0030308//negative regulation of cell growth;GO:0032446//protein modification by small protein conjugation;GO:0010977//negative regulation of neuron projection development;GO:0030098//lymphocyte differentiation;GO:0030307//positive regulation of cell growth;GO:0006366//transcription from RNA polymerase II promoter;GO:0032460//negative regulation of protein oligomerization;GO:0030308//negative regulation of cell growth;GO:0032446//protein modification by small protein conjugation;GO:0010977//negative regulation of neuron projection development;GO:0030098//lymphocyte differentiation;GO:0006351//transcription, DNA-templated;GO:0030307//positive regulation of cell growth;GO:0030308//negative regulation of cell growth;GO:0032446//protein modification by small protein conjugation;GO:0010977//negative regulation of neuron projection development;GO:0030098//lymphocyte differentiation" gi|558101720|ref|XP_006083372.1|/5.6484e-149/PREDICTED: B-cell lymphoma/leukemia 11A isoform X5 [Myotis lucifugus] 54446 13389 2.556666667 2.566666667 0.005631868 Up 0.084010305 Nfat5 nuclear factor of activated T cells 5 K17335|1|0.0|2025|mmu:54446|nuclear factor of activated T-cells 5 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0001071//nucleic acid binding transcription factor activity GO:0033173//calcineurin-NFAT signaling cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0033173//calcineurin-NFAT signaling cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0033173//calcineurin-NFAT signaling cascade;GO:0006366//transcription from RNA polymerase II promoter gi|163937838|ref|NP_598718.2|/0/nuclear factor of activated T-cells 5 isoform a [Mus musculus] 68328 1548 2.816666667 2.83 0.006813212 Up 0.084010305 Rab13 "RAB13, member RAS oncogene family" K06109|1|2e-85|318|mmu:68328|Ras-related protein Rab-13 GO:0012506//vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0019898//extrinsic component of membrane;GO:0012506//vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0043296//apical junction complex;GO:0019898//extrinsic component of membrane GO:0032550;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0017111//nucleoside-triphosphatase activity GO:0015031//protein transport;GO:0022610;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction;GO:0015031//protein transport;GO:0022610;GO:0009154//purine ribonucleotide catabolic process;GO:0035556//intracellular signal transduction gi|21311975|ref|NP_080953.1|/1.99348e-84/ras-related protein Rab-13 isoform 1 [Mus musculus] 50781 3357 0.783333333 0.776666667 -0.012330802 Down 0.084010305 Dkk3 dickkopf WNT signaling pathway inhibitor 3 K02165|1|7e-10|69.3|cjo:107315640|dickkopf - - - - 12524 2539 1.08 1.09 0.013296823 Up 0.084010305 Cd86 CD86 antigen K05413|1|2e-157|559|mmu:12524|CD86 antigen GO:0043227//membrane-bounded organelle;GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0005515//protein binding GO:0032496//response to lipopolysaccharide;GO:0042102//positive regulation of T cell proliferation;GO:0034097//response to cytokine;GO:0010038//response to metal ion;GO:0002286//T cell activation involved in immune response;GO:0002221//pattern recognition receptor signaling pathway;GO:0044767//single-organism developmental process;GO:0001773//myeloid dendritic cell activation;GO:0002665 gi|161484599|ref|NP_062261.3|/1.41342e-156/T-lymphocyte activation antigen CD86 precursor [Mus musculus] 216560 2443 0.96 0.953333333 -0.010053665 Down 0.084010305 Wdpcp WD repeat containing planar cell polarity effector - GO:0044459;GO:0043232;GO:0044444//cytoplasmic part;GO:0005930//axoneme - GO:0048858//cell projection morphogenesis;GO:0008360//regulation of cell shape;GO:0007010//cytoskeleton organization;GO:0008104//protein localization gi|568970124|ref|XP_006514701.1|/0/PREDICTED: WD repeat-containing and planar cell polarity effector protein fritz homolog isoform X3 [Mus musculus] 72269 833 0.796666667 0.79 -0.012123559 Down 0.084010305 Cda cytidine deaminase K01489|1|4e-80|300|mmu:72269|cytidine deaminase [EC:3.5.4.5] GO:0044444//cytoplasmic part "GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0036094//small molecule binding" GO:0016049//cell growth;GO:0051260//protein homooligomerization;GO:0006216//cytidine catabolic process;GO:0006140 gi|58037289|ref|NP_082452.1|/3.1432e-79/cytidine deaminase [Mus musculus] 76338 2770 2.6 2.613333333 0.00737953 Up 0.084010305 Rab2b "RAB2B, member RAS oncogene family" K07878|1|5e-121|438|mmu:76338|Ras-related protein Rab-2B GO:0043231//intracellular membrane-bounded organelle;GO:0031090//organelle membrane;GO:0012505//endomembrane system GO:0032550 GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization;GO:0006887//exocytosis gi|30525051|ref|NP_766189.1|/4.02859e-120/ras-related protein Rab-2B [Mus musculus] 26896 5747.45 6.54 6.56 0.004405179 Up 0.08343676 Med14 mediator complex subunit 14 K15156|1|0.0|2559|mmu:26896|mediator of RNA polymerase II transcription subunit 14 GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0031981//nuclear lumen "GO:0008134//transcription factor binding;GO:0003713//transcription coactivator activity;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0008134//transcription factor binding;GO:0003713//transcription coactivator activity;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0032502//developmental process;GO:0006366//transcription from RNA polymerase II promoter gi|115270972|ref|NP_036135.3|/0/mediator of RNA polymerase II transcription subunit 14 isoform b [Mus musculus] 544752 4881.55 7.32 7.34 0.003936415 Up 0.08343676 Tug1 taurine upregulated gene 1 - - - - - 16801 3377.29 27.33666667 27.32 -0.000879853 Down 0.08343676 Arhgef1 Rho guanine nucleotide exchange factor (GEF) 1 K12330|1|0.0|1597|mmu:16801|Rho guanine nucleotide exchange factor 1 GO:0044424;GO:0044424;GO:0044424;GO:0044424;GO:0044424 GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity;GO:0008289//lipid binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0008047//enzyme activator activity;GO:0008289//lipid binding GO:0007266//Rho protein signal transduction;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0007266//Rho protein signal transduction;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0007266//Rho protein signal transduction;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0007266//Rho protein signal transduction;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0007266//Rho protein signal transduction;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway "gi|148692358|gb|EDL24305.1|/0/Rho guanine nucleotide exchange factor (GEF) 1, isoform CRA_d, partial [Mus musculus]" 67772 8190 5.86 5.876666667 0.004097404 Up 0.08343676 Chd8 chromodomain helicase DNA binding protein 8 K04494|1|0.0|4299|mmu:67772|chromodomain helicase DNA binding protein 8 [EC:3.6.4.12] GO:0044665//MLL1/2 complex "GO:0042393//histone binding;GO:0032550;GO:0003676//nucleic acid binding;GO:0004386//helicase activity;GO:0019904//protein domain specific binding;GO:0042623//ATPase activity, coupled" GO:0006383//transcription from RNA polymerase III promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0006915//apoptotic process;GO:0043009//chordate embryonic development;GO:0006338//chromatin remodeling;GO:0032392//DNA geometric change gi|119392064|ref|NP_963999.2|/0/chromodomain-helicase-DNA-binding protein 8 [Mus musculus] 17133 1954.96 15.47333333 15.45 -0.002177184 Down 0.08343676 Maff "v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)" K09037|1|2e-48|196|mmu:17133|transcription factor MAFF/G/K - GO:0003677//DNA binding "GO:0009913//epidermal cell differentiation;GO:0007519//skeletal muscle tissue development;GO:0006351//transcription, DNA-templated" gi|672060207|ref|XP_006242091.2|/6.60059e-84/PREDICTED: transcription factor MafF isoform X1 [Rattus norvegicus] 20684 2659.88 17.83 17.84666667 0.001347935 Up 0.08343676 Sp100 nuclear antigen Sp100 K15413|1|0.0|906|mmu:20684|nuclear autoantigen Sp-100 - - - - 72399 3737 13.83 13.85 0.00208482 Up 0.08343676 Brap BRCA1 associated protein K10632|1|0.0|1113|mmu:72399|BRCA1-associated protein [EC:2.3.2.27] GO:0044424;GO:0044424;GO:0044424 GO:0005048//signal sequence binding;GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0005048//signal sequence binding;GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0005048//signal sequence binding;GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0019787//ubiquitin-like protein transferase activity GO:0007264//small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction gi|575501688|ref|NP_001276473.1|/0/BRCA1-associated protein isoform 3 [Mus musculus] 20441 2470.3 48.44 48.41666667 -0.000695107 Down 0.08343676 St3gal3 "ST3 beta-galactoside alpha-2,3-sialyltransferase 3" "K00781|1|0.0|689|mmu:20441|N-acetyllactosaminide alpha-2,3-sialyltransferase (sialyltransferase 6) [EC:2.4.99.6]" GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane GO:0008373//sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0008373//sialyltransferase activity;GO:0008373//sialyltransferase activity GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process;GO:0006464//cellular protein modification process "gi|532054785|ref|XP_005370111.1|/0/PREDICTED: CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase [Microtus ochrogaster]" 223739 5032 8.55 8.566666667 0.002809534 Up 0.08343676 5031439G07Rik RIKEN cDNA 5031439G07 gene - - - - gi|85701776|ref|NP_001028445.1|/0/uncharacterized protein KIAA0930 homolog [Mus musculus] 76740 5210 10.26333333 10.28 0.002340898 Up 0.08343676 Efr3a EFR3 homolog A - - - - - 69188 7258 9.776666667 9.76 -0.002461517 Down 0.08343676 Kmt2e lysine (K)-specific methyltransferase 2E K09189|1|0.0|3114|mmu:69188|histone-lysine N-methyltransferase MLL5 [EC:2.1.1.43] - - - gi|262527254|ref|NP_081260.1|/0/histone-lysine N-methyltransferase 2E [Mus musculus] 77853 4899 5.066666667 5.083333333 0.004737919 Up 0.08343676 Msl2 male-specific lethal 2 homolog (Drosophila) K13164|1|0.0|1050|mmu:77853|male-specific lethal 2 - - - - 13831 3814.35 8.426666667 8.41 -0.002856257 Down 0.08343676 Epc1 enhancer of polycomb homolog 1 (Drosophila) K11322|1|0.0|1311|mmu:13831|enhancer of polycomb-like protein GO:0005635//nuclear envelope;GO:0035267//NuA4 histone acetyltransferase complex;GO:0005635//nuclear envelope;GO:0035267//NuA4 histone acetyltransferase complex;GO:0005635//nuclear envelope;GO:0035267//NuA4 histone acetyltransferase complex GO:0008080//N-acetyltransferase activity;GO:0008080//N-acetyltransferase activity;GO:0008080//N-acetyltransferase activity GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0010629//negative regulation of gene expression;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0010629//negative regulation of gene expression;GO:0016573//histone acetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0040007//growth;GO:0010629//negative regulation of gene expression;GO:0016573//histone acetylation gi|6679655|ref|NP_031961.1|/0/enhancer of polycomb homolog 1 isoform 1 [Mus musculus] 384061 2718 297.09 297.1133333 0.000113304 Up 0.08343676 Fndc5 fibronectin type III domain containing 5 - GO:0044439;GO:0031224//intrinsic component of membrane GO:0005102//receptor binding GO:0014823//response to activity;GO:0045600//positive regulation of fat cell differentiation "gi|148698266|gb|EDL30213.1|/1.95269e-119/fibronectin type III domain containing 5, isoform CRA_a, partial [Mus musculus]" 68828 2038 14.75666667 14.77666667 0.001953989 Up 0.08343676 Sync syncoilin K10377|1|0.0|816|mmu:68828|syncoilin 1 GO:0043234//protein complex;GO:0005886//plasma membrane;GO:0045202//synapse;GO:0031674//I band GO:0005488//binding GO:0044763 gi|47059478|ref|NP_075974.3|/0/syncoilin [Mus musculus] 69802 2259 7.986666667 8.003333333 0.003007495 Up 0.08343676 Cox11 cytochrome c oxidase assembly protein 11 K02258|1|3e-155|551|mmu:69802|cytochrome c oxidase assembly protein subunit 11 GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding - "gi|39841021|ref|NP_950173.1|/2.56776e-154/cytochrome c oxidase assembly protein COX11, mitochondrial [Mus musculus]" 18949 3469 7.613333333 7.596666667 -0.003161726 Down 0.08343676 Pnn pinin K13114|1|0.0|726|mmu:18949|pinin GO:0043234//protein complex;GO:0005681//spliceosomal complex;GO:0016604//nuclear body;GO:0005911//cell-cell junction;GO:0016020//membrane - GO:0000377;GO:0007155//cell adhesion "gi|148704736|gb|EDL36683.1|/0/pinin, partial [Mus musculus]" 75723 8951 11.19333333 11.17 -0.003010544 Down 0.08343676 Amotl1 angiomotin-like 1 K06104|1|0.0|1605|mmu:75723|angiomotin like 1 GO:0043296//apical junction complex;GO:0044459;GO:0031982//vesicle;GO:0031252//cell leading edge GO:0005515//protein binding GO:0035556//intracellular signal transduction;GO:0010595//positive regulation of endothelial cell migration;GO:0007166//cell surface receptor signaling pathway gi|124487107|ref|NP_001074864.1|/0/angiomotin-like protein 1 [Mus musculus] 19024 3757.14 8.033333333 8.053333333 0.003587308 Up 0.08343676 Ppfibp2 "PTPRF interacting protein, binding protein 2 (liprin beta 2)" - - GO:0003824//catalytic activity;GO:0003824//catalytic activity GO:0006259//DNA metabolic process;GO:0006259//DNA metabolic process gi|568949833|ref|XP_006507506.1|/0/PREDICTED: liprin-beta-2 isoform X1 [Mus musculus] 66776 2866 13.96 13.93666667 -0.002413399 Down 0.08343676 Pisd-ps3 "phosphatidylserine decarboxylase, pseudogene 3" K01613|1|2e-142|280|myd:102754521|phosphatidylserine decarboxylase [EC:4.1.1.65] - - - "gi|148705450|gb|EDL37397.1|/1.12113e-155/mCG2531, isoform CRA_a [Mus musculus]" 57275 668 9.383333333 9.366666667 -0.002564792 Down 0.08343676 Lenep lens epithelial protein - GO:0044424 - - gi|10048454|ref|NP_065263.1|/7.19195e-29/lens epithelial cell protein LEP503 [Mus musculus] 108079 8201 12.25666667 12.23666667 -0.002356062 Down 0.08343676 Prkaa2 "protein kinase, AMP-activated, alpha 2 catalytic subunit" "K07198|1|0.0|1079|mmu:108079|5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]" - - - - 230379 3393.08 23.55 23.57333333 0.001428714 Up 0.08343676 Acer2 alkaline ceramidase 2 K01441|1|1e-165|587|mmu:230379|alkaline ceramidase [EC:3.5.1.23] GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane;GO:0031228//intrinsic component of Golgi membrane "GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0016811//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds" GO:0006670//sphingosine metabolic process;GO:0008283//cell proliferation;GO:0007162//negative regulation of cell adhesion;GO:0006915//apoptotic process;GO:0060051//negative regulation of protein glycosylation;GO:0033993//response to lipid;GO:0006670//sphingosine metabolic process;GO:0008283//cell proliferation;GO:0007162//negative regulation of cell adhesion;GO:0006915//apoptotic process;GO:0060051//negative regulation of protein glycosylation;GO:0033993//response to lipid;GO:0006670//sphingosine metabolic process;GO:0008283//cell proliferation;GO:0007162//negative regulation of cell adhesion;GO:0006915//apoptotic process;GO:0060051//negative regulation of protein glycosylation;GO:0033993//response to lipid gi|21314858|ref|NP_647467.1|/1.12487e-164/alkaline ceramidase 2 isoform 1 [Mus musculus] 17354 5002.87 5.643333333 5.626666667 -0.004267069 Down 0.08343676 Mllt10 "myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10" K05175|1|2e-58|231|ocu:100339376|gamma-aminobutyric acid receptor subunit alpha;K11348|3|1e-24|119|sko:100372837|bromodomain and PHD finger-containing protein 1 - GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding;GO:0046872//metal ion binding GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter gi|47271507|ref|NP_034934.2|/0/protein AF-10 isoform 1 [Mus musculus] 244216 1230 11.82666667 11.85 0.00284355 Up 0.08343676 Zfp771 zinc finger protein 771 K09228|1|6e-88|327|asn:102387496|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|880856389|ref|XP_005064424.2|/1.00017e-166/PREDICTED: zinc finger protein 771 [Mesocricetus auratus] 72026 1520 5.146666667 5.13 -0.004679521 Down 0.08343676 Trmu tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase K00566|1|0.0|849|mmu:72026|tRNA-specific 2-thiouridylase [EC:2.8.1.-] GO:0043231//intracellular membrane-bounded organelle "GO:0008175//tRNA methyltransferase activity;GO:0016782//transferase activity, transferring sulfur-containing groups;GO:0003723//RNA binding;GO:0032550" GO:0006399//tRNA metabolic process gi|21312518|ref|NP_082339.1|/0/mitochondrial tRNA-specific 2-thiouridylase 1 [Mus musculus] 56041 3914 11.26333333 11.24 -0.002991814 Down 0.08343676 Uso1 USO1 vesicle docking factor K00876|1|9e-28|129|hmg:100214619|uridine kinase [EC:2.7.1.48];K04443|2|2e-09|67.8|tup:102483974|mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1];K20282|3|9e-07|59.3|cjo:107306467|GRIP and coiled-coil domain-containing protein 2 GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0022892//substrate-specific transporter activity GO:0048193//Golgi vesicle transport;GO:0006906//vesicle fusion;GO:0015031//protein transport gi|23956096|ref|NP_062363.1|/0/general vesicular transport factor p115 [Mus musculus] 170719 3229.9 13.57333333 13.59 0.001770395 Up 0.08343676 Oxr1 oxidation resistance 1 K12587|1|3e-41|174|bfo:BRAFLDRAFT_124886|exosome complex component MTR3;K19607|3|1e-09|68.9|xma:102223795|X-linked retinitis pigmentosa GTPase regulator;K17498|4|1e-06|58.9|aam:106484470|transcription factor SPN1;K14000|5|2e-06|58.5|ola:101165419|ribosome-binding protein 1 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen - GO:0006950//response to stress;GO:0044036;GO:0006950//response to stress;GO:0044036;GO:0006950//response to stress;GO:0044036;GO:0044036;GO:0044036 gi|194328708|ref|NP_001123638.1|/0/oxidation resistance protein 1 isoform E [Mus musculus] 66422 648 22.88 22.90333333 0.00147053 Up 0.08343676 Dctpp1 dCTP pyrophosphatase 1 K16904|1|1e-84|314|mmu:66422|dCTP diphosphatase [EC:3.6.1.12] GO:0044444//cytoplasmic part GO:0019103//pyrimidine nucleotide binding;GO:0046872//metal ion binding;GO:0047429//nucleoside-triphosphate diphosphatase activity GO:0051260//protein homooligomerization;GO:0009141//nucleoside triphosphate metabolic process gi|12963573|ref|NP_075692.1|/9.38622e-84/dCTP pyrophosphatase 1 [Mus musculus] 671535 3361.58 6.703333333 6.723333333 0.004298002 Up 0.08343676 Parp10 "poly (ADP-ribose) polymerase family, member 10" K15261|1|0.0|1659|mmu:671535|poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30] GO:0044424;GO:0044424 - GO:0008285//negative regulation of cell proliferation;GO:0006471//protein ADP-ribosylation;GO:0001672//regulation of chromatin assembly or disassembly;GO:0008285//negative regulation of cell proliferation;GO:0006471//protein ADP-ribosylation;GO:0001672//regulation of chromatin assembly or disassembly gi|254675288|ref|NP_001157047.1|/0/poly [ADP-ribose] polymerase 10 [Mus musculus] 11909 4044.72 8.116666667 8.093333333 -0.004153351 Down 0.08343676 Atf2 activating transcription factor 2 K04450|1|0.0|742|umr:103659593|cyclic AMP-dependent transcription factor ATF-2 GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0031981//nuclear lumen;GO:0031981//nuclear lumen "GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003713//transcription coactivator activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0019900//kinase binding;GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003713//transcription coactivator activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0019900//kinase binding;GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003713//transcription coactivator activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0019900//kinase binding;GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0046983//protein dimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0003713//transcription coactivator activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0019900//kinase binding;GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0046983//protein dimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0003713//transcription coactivator activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0019900//kinase binding;GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003713//transcription coactivator activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0019900//kinase binding;GO:0046914//transition metal ion binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003713//transcription coactivator activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0019900//kinase binding" "GO:0003007//heart morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0000165//MAPK cascade;GO:0030154//cell differentiation;GO:0032906;GO:0003007//heart morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0000165//MAPK cascade;GO:0030154//cell differentiation;GO:0032906;GO:0003007//heart morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0000165//MAPK cascade;GO:0030154//cell differentiation;GO:0032906;GO:0003007//heart morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0006950//response to stress;GO:0032906;GO:0003007//heart morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0006950//response to stress;GO:0032906;GO:0003007//heart morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0000165//MAPK cascade;GO:0030154//cell differentiation;GO:0032906;GO:0003007//heart morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0000165//MAPK cascade;GO:0030154//cell differentiation;GO:0032906" gi|545555287|ref|XP_005640391.1|/0/PREDICTED: cyclic AMP-dependent transcription factor ATF-2 isoform X1 [Canis lupus familiaris] 107650 3786 10.52333333 10.5 -0.003202432 Down 0.08343676 Pi4kb "phosphatidylinositol 4-kinase, catalytic, beta polypeptide" K19801|1|0.0|1003|cge:100770133|phosphatidylinositol 4-kinase B [EC:2.7.1.67] GO:0031966//mitochondrial membrane;GO:0031966//mitochondrial membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031966//mitochondrial membrane GO:0032550;GO:0052742;GO:0032550;GO:0052742;GO:0032550;GO:0052742 GO:0046488//phosphatidylinositol metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0048017//inositol lipid-mediated signaling;GO:0046488//phosphatidylinositol metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0048017//inositol lipid-mediated signaling;GO:0006897//endocytosis;GO:0046488//phosphatidylinositol metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0048017//inositol lipid-mediated signaling gi|537264899|gb|ERE90758.1|/0/phosphatidylinositol 4-kinase beta isoform 2 [Cricetulus griseus] 12475 1681 6.916666667 6.936666667 0.004165629 Up 0.08343676 Cd14 CD14 antigen K04391|1|0.0|707|mmu:12475|CD14 antigen GO:0016021//integral component of membrane;GO:0044464;GO:0044421 GO:0008289//lipid binding GO:0006952//defense response;GO:0010038//response to metal ion;GO:0097305//response to alcohol;GO:0001819//positive regulation of cytokine production;GO:0050663//cytokine secretion;GO:0034097//response to cytokine;GO:0006897//endocytosis;GO:0032496//response to lipopolysaccharide;GO:0070391 gi|6753332|ref|NP_033971.1|/0/monocyte differentiation antigen CD14 precursor [Mus musculus] 18008 6143 5.356666667 5.363333333 0.001794397 Up 0.08221445 Nes nestin K07609|1|0.0|3216|mmu:18008|nestin GO:0043234//protein complex;GO:0005856//cytoskeleton GO:0032403//protein complex binding;GO:0048020//CCR chemokine receptor binding GO:0009314//response to radiation;GO:0007417//central nervous system development;GO:0043010//camera-type eye development;GO:0043393//regulation of protein binding;GO:0044092//negative regulation of molecular function;GO:0006915//apoptotic process;GO:0000902//cell morphogenesis;GO:0030842;GO:0042221//response to chemical;GO:0009991//response to extracellular stimulus;GO:0030154//cell differentiation;GO:0008284//positive regulation of cell proliferation "gi|148683377|gb|EDL15324.1|/0/nestin, isoform CRA_a, partial [Mus musculus]" 19054 4479.65 10.08 10.09333333 0.001907066 Up 0.08221445 Ppp2r3d "protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta" K11583|1|2e-149|533|mmu:19054|serine/threonine-protein phosphatase 2A regulatory subunit B'' - GO:0046872//metal ion binding;GO:0019888//protein phosphatase regulator activity;GO:0046872//metal ion binding;GO:0019888//protein phosphatase regulator activity;GO:0046872//metal ion binding;GO:0019888//protein phosphatase regulator activity;GO:0046872//metal ion binding;GO:0019888//protein phosphatase regulator activity GO:0019222//regulation of metabolic process;GO:0008283//cell proliferation;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0006464//cellular protein modification process;GO:0019222//regulation of metabolic process;GO:0008283//cell proliferation;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0006464//cellular protein modification process;GO:0019222//regulation of metabolic process;GO:0008283//cell proliferation;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0006464//cellular protein modification process;GO:0019222//regulation of metabolic process;GO:0008283//cell proliferation;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0006464//cellular protein modification process gi|74226247|dbj|BAE25309.1|/2.07105e-175/unnamed protein product [Mus musculus] 30839 2359 56.10666667 56.11666667 0.000257111 Up 0.08221445 Fbxw5 F-box and WD-40 domain protein 5 K10263|1|0.0|1152|mmu:30839|F-box and WD-40 domain protein 5 GO:0031461//cullin-RING ubiquitin ligase complex GO:0019900//kinase binding GO:0007098//centrosome cycle;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032446//protein modification by small protein conjugation gi|7305047|ref|NP_038936.1|/0/F-box/WD repeat-containing protein 5 [Mus musculus] 66151 1149.92 47.09 47.07666667 -0.000408551 Down 0.08221445 Prr13 proline rich 13 - - - - "gi|148672032|gb|EDL03979.1|/7.86476e-11/proline rich 13, isoform CRA_b, partial [Mus musculus]" 545539 1464 9.526666667 9.513333333 -0.002020582 Down 0.08221445 Gm15417 predicted gene 15417 - - - - - 67014 2159 11.8 11.80666667 0.000814852 Up 0.08221445 Mina myc induced nuclear antigen K16914|1|4e-54|215|dre:560815|bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [EC:1.14.11.- 1.14.11.27] GO:0043234//protein complex;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part "GO:0043169//cation binding;GO:0016701//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" "GO:0044710;GO:0022613//ribonucleoprotein complex biogenesis;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation" gi|256355182|ref|NP_080186.3|/0/bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA [Mus musculus] 68099 1920 7.876666667 7.883333333 0.001220554 Up 0.08221445 Fam92a "family with sequence similarity 92, member A" K15421|1|2e-49|199|nvi:100123748|secretion-regulating guanine nucleotide exchange factor;K10837|2|5e-37|158|hmg:100200454|O-phosphoseryl-tRNA(Sec) kinase [EC:2.7.1.164];K02258|3|2e-09|67.0|smm:Smp_141470|cytochrome c oxidase assembly protein subunit 11 - - - gi|894216159|ref|NP_001297672.1|/0/protein FAM92A1 isoform 2 [Mus musculus] 227743 3280.81 17.36 17.35 -0.000831285 Down 0.08221445 Mapkap1 mitogen-activated protein kinase associated protein 1 K20410|1|0.0|1000|mmu:227743|target of rapamycin complex 2 subunit MAPKAP1 GO:0016020//membrane;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0031982//vesicle;GO:0043231//intracellular membrane-bounded organelle "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0016772//transferase activity, transferring phosphorus-containing groups" GO:0050896//response to stimulus;GO:0006796//phosphate-containing compound metabolic process;GO:0050896//response to stimulus;GO:0006796//phosphate-containing compound metabolic process;GO:0050896//response to stimulus;GO:0006796//phosphate-containing compound metabolic process gi|28893485|ref|NP_796319.1|/0/target of rapamycin complex 2 subunit MAPKAP1 isoform a [Mus musculus] 26450 2183 7.2 7.213333333 0.002669187 Up 0.08221445 Rbbp9 retinoblastoma binding protein 9 K07002|1|4e-100|368|mmu:26450|uncharacterized protein - - - - 17391 4306 4.693333333 4.7 0.002047829 Up 0.08221445 Mmp24 matrix metallopeptidase 24 K08002|1|0.0|1028|mmu:17391|matrix metalloproteinase-24 (membrane-inserted) [EC:3.4.24.-] GO:0031012//extracellular matrix;GO:0016021//integral component of membrane GO:0008233//peptidase activity;GO:0046914//transition metal ion binding;GO:0030234//enzyme regulator activity GO:0019538//protein metabolic process;GO:0044093 gi|5689227|dbj|BAA82966.1|/0/membrane-type-5 matrix metalloproteinase [Mus musculus] 16413 1874 15.17333333 15.18 0.000633734 Up 0.08221445 Itgb1bp1 integrin beta 1 binding protein 1 K20058|1|5e-83|311|mmu:16413|integrin beta-1-binding protein 1 GO:0031252//cell leading edge;GO:0044444//cytoplasmic part GO:0005102//receptor binding GO:0007166//cell surface receptor signaling pathway;GO:0031589//cell-substrate adhesion "gi|148702079|gb|EDL34026.1|/4.63609e-82/integrin beta 1 binding protein 1, isoform CRA_a, partial [Mus musculus]" 245474 2803 8.013333333 8.006666667 -0.001200745 Down 0.08221445 Dkc1 "dyskeratosis congenita 1, dyskerin" K11131|1|0.0|889|mmu:245474|H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-] - - - gi|9931991|emb|CAC04528.1|/0/DYSKERIN [Mus musculus] 208372 1404 4.136666667 4.13 -0.002326928 Down 0.08221445 Asb18 ankyrin repeat and SOCS box-containing 18 K10340|1|0.0|853|mmu:208372|ankyrin repeat and SOCS box protein 18 - - GO:0007165//signal transduction gi|21040227|ref|NP_631891.1|/0/ankyrin repeat and SOCS box protein 18 [Mus musculus] 80904 2030 21.98 21.99333333 0.000874891 Up 0.08221445 Dtx3 "deltex 3, E3 ubiquitin ligase" K06058|1|6e-158|560|rno:500847|deltex [EC:2.3.2.27] - - - - 67039 4244 14.12666667 14.14 0.001361033 Up 0.08221445 Rbm25 RNA binding motif protein 25 K12822|1|5e-143|491|hgl:101716537|RNA-binding protein 25 GO:0016604//nuclear body GO:0003723//RNA binding "GO:0012501//programmed cell death;GO:0000380//alternative mRNA splicing, via spliceosome" gi|512949724|ref|XP_004837307.1|/4.50686e-142/PREDICTED: RNA-binding protein 25 isoform X1 [Heterocephalus glaber] 225875 2930 4.13 4.136666667 0.002326928 Up 0.08221445 Lrfn4 leucine rich repeat and fibronectin type III domain containing 4 K16357|1|0.0|1078|mmu:225875|leucine-rich repeat and fibronectin type-III domain-containing protein 4 GO:0031224//intrinsic component of membrane - - gi|31559904|ref|NP_700437.2|/0/leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor [Mus musculus] 20184 2697 5.013333333 5 -0.003842066 Down 0.08221445 Uimc1 ubiquitin interaction motif containing 1 - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0031593//polyubiquitin binding;GO:0042974//retinoic acid receptor binding;GO:0031593//polyubiquitin binding;GO:0042974//retinoic acid receptor binding;GO:0031593//polyubiquitin binding;GO:0042974//retinoic acid receptor binding "GO:0006351//transcription, DNA-templated;GO:0000077//DNA damage checkpoint;GO:0016578//histone deubiquitination;GO:0009314//response to radiation;GO:0006281//DNA repair;GO:0006351//transcription, DNA-templated;GO:0000077//DNA damage checkpoint;GO:0016578//histone deubiquitination;GO:0009314//response to radiation;GO:0006281//DNA repair;GO:0006351//transcription, DNA-templated;GO:0000077//DNA damage checkpoint;GO:0016578//histone deubiquitination;GO:0009314//response to radiation;GO:0006281//DNA repair" gi|229462765|sp|Q5U5Q9.2|UIMC1_MOUSE/0/RecName: Full=BRCA1-A complex subunit RAP80; AltName: Full=Receptor-associated protein 80; AltName: Full=Ubiquitin interaction motif-containing protein 1 231600 3180 4.253333333 4.26 0.002259507 Up 0.08221445 Chfr checkpoint with forkhead and ring finger domains K10644|1|0.0|961|cge:100771287|E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27] GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body;GO:0016604//nuclear body GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046914//transition metal ion binding;GO:0036094//small molecule binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0046872//metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0000075//cell cycle checkpoint;GO:0019941//modification-dependent protein catabolic process;GO:0000087//mitotic M phase;GO:0016567//protein ubiquitination;GO:0000075//cell cycle checkpoint;GO:0019941//modification-dependent protein catabolic process;GO:0000087//mitotic M phase;GO:0016567//protein ubiquitination;GO:0000075//cell cycle checkpoint;GO:0019941//modification-dependent protein catabolic process;GO:0000087//mitotic M phase;GO:0016567//protein ubiquitination;GO:0000075//cell cycle checkpoint;GO:0019941//modification-dependent protein catabolic process;GO:0000087//mitotic M phase;GO:0016567//protein ubiquitination;GO:0000278//mitotic cell cycle;GO:0000075//cell cycle checkpoint;GO:0019941//modification-dependent protein catabolic process;GO:0016567//protein ubiquitination gi|575771762|ref|NP_001276507.1|/0/E3 ubiquitin-protein ligase CHFR isoform 3 [Mus musculus] 76547 1576 6.893333333 6.906666667 0.002787817 Up 0.08221445 Tmem101 transmembrane protein 101 - GO:0031224//intrinsic component of membrane GO:0060089 GO:0007249//I-kappaB kinase/NF-kappaB signaling gi|262118243|ref|NP_083925.2|/3.39174e-144/transmembrane protein 101 [Mus musculus] 228889 2592 8.883333333 8.893333333 0.001623134 Up 0.08221445 Ddx27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 K13181|1|0.0|1149|mmu:228889|ATP-dependent RNA helicase DDX27 [EC:3.6.4.13] GO:0043231//intracellular membrane-bounded organelle "GO:0042623//ATPase activity, coupled;GO:0032550" - gi|124249330|ref|NP_694705.2|/0/probable ATP-dependent RNA helicase DDX27 [Mus musculus] 11492 6057.28 4.446666667 4.433333333 -0.004332421 Down 0.08221445 Adam19 a disintegrin and metallopeptidase domain 19 (meltrin beta) K08608|1|0.0|1703|mmu:11492|disintegrin and metalloproteinase domain-containing protein 19 [EC:3.4.24.-] GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding;GO:0004175//endopeptidase activity;GO:0046914//transition metal ion binding;GO:0019904//protein domain specific binding GO:0007166//cell surface receptor signaling pathway;GO:0033619//membrane protein proteolysis;GO:0044767//single-organism developmental process;GO:0007166//cell surface receptor signaling pathway;GO:0033619//membrane protein proteolysis;GO:0044767//single-organism developmental process;GO:0007166//cell surface receptor signaling pathway;GO:0033619//membrane protein proteolysis;GO:0044767//single-organism developmental process gi|6752966|ref|NP_033746.1|/0/disintegrin and metalloproteinase domain-containing protein 19 isoform 1 preproprotein [Mus musculus] 230700 4738.16 8.443333333 8.456666667 0.002276442 Up 0.08221445 Foxj3 forkhead box J3 K09403|1|0.0|962|mmu:230700|forkhead box protein J2/3 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|27370018|ref|NP_766287.1|/0/forkhead box protein J3 isoform 1 [Mus musculus] 66892 2513 25.3 25.31 0.000570123 Up 0.08221445 Eif4e3 eukaryotic translation initiation factor 4E member 3 K03259|1|1e-49|201|cin:100187540|translation initiation factor 4E GO:0034518//RNA cap binding complex;GO:0044444//cytoplasmic part "GO:0008135//translation factor activity, RNA binding" GO:0007166//cell surface receptor signaling pathway;GO:0006412//translation gi|13385302|ref|NP_080105.1|/1.2021e-99/eukaryotic translation initiation factor 4E type 3 [Mus musculus] 77037 992 14.24666667 14.25666667 0.001012299 Up 0.08221445 Mrap melanocortin 2 receptor accessory protein - GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0031779//melanocortin receptor binding GO:0034613//cellular protein localization;GO:0006171//cAMP biosynthetic process;GO:0045444//fat cell differentiation gi|27229245|ref|NP_084120.1|/2.00218e-60/melanocortin-2 receptor accessory protein [Mus musculus] 328561 1986 2.236666667 2.23 -0.004306556 Down 0.08221445 Apol10b apolipoprotein L 10B K14480|1|1e-159|566|mmu:328561|apolipoprotein L - - - - 73192 5989 5.99 5.996666667 0.001604778 Up 0.08221445 Xpot "exportin, tRNA (nuclear export receptor for tRNAs)" K14288|1|0.0|1865|mmu:73192|exportin-T - - - gi|124486686|ref|NP_001074525.1|/0/exportin-T [Mus musculus] 66614 1646.74 10.26 10.27333333 0.00187363 Up 0.08221445 Gpatch4 G patch domain containing 4 K11135|1|7e-09|64.7|ola:101168834|Pin2-interacting protein X1 - GO:0097159//organic cyclic compound binding;GO:0097159//organic cyclic compound binding - gi|160948592|ref|NP_079939.3|/0/G patch domain-containing protein 4 [Mus musculus] 15461 2181.98 26.89333333 26.88 -0.000715445 Down 0.08221445 Hras Harvey rat sarcoma virus oncogene K02833|1|2e-98|362|ngi:103751075|GTPase HRas GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0005515//protein binding GO:0000075//cell cycle checkpoint;GO:0043405//regulation of MAP kinase activity;GO:0008284//positive regulation of cell proliferation;GO:0042692//muscle cell differentiation;GO:0031532//actin cytoskeleton reorganization;GO:0051705;GO:0031346//positive regulation of cell projection organization;GO:0043410//positive regulation of MAPK cascade;GO:0009653//anatomical structure morphogenesis;GO:0010586//miRNA metabolic process;GO:0007569//cell aging;GO:0016477//cell migration;GO:0012502//induction of programmed cell death;GO:0007254//JNK cascade;GO:0016601//Rac protein signal transduction;GO:0006935//chemotaxis;GO:0007599//hemostasis;GO:0006260//DNA replication;GO:0002376//immune system process;GO:0006366//transcription from RNA polymerase II promoter;GO:0007632//visual behavior;GO:0051259//protein oligomerization;GO:0016192//vesicle-mediated transport;GO:0038127//ERBB signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0048168//regulation of neuronal synaptic plasticity;GO:0000075//cell cycle checkpoint;GO:0043405//regulation of MAP kinase activity;GO:0008284//positive regulation of cell proliferation;GO:0042692//muscle cell differentiation;GO:0031532//actin cytoskeleton reorganization;GO:0051705;GO:0031346//positive regulation of cell projection organization;GO:0043410//positive regulation of MAPK cascade;GO:0009653//anatomical structure morphogenesis;GO:0010586//miRNA metabolic process;GO:0007569//cell aging;GO:0016477//cell migration;GO:0012502//induction of programmed cell death;GO:0007254//JNK cascade;GO:0016601//Rac protein signal transduction;GO:0006935//chemotaxis;GO:0007599//hemostasis;GO:0006260//DNA replication;GO:0002376//immune system process;GO:0006366//transcription from RNA polymerase II promoter;GO:0007632//visual behavior;GO:0051259//protein oligomerization;GO:0016192//vesicle-mediated transport;GO:0038127//ERBB signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0048168//regulation of neuronal synaptic plasticity;GO:0000075//cell cycle checkpoint;GO:0043405//regulation of MAP kinase activity;GO:0008284//positive regulation of cell proliferation;GO:0042692//muscle cell differentiation;GO:0031532//actin cytoskeleton reorganization;GO:0051705;GO:0031346//positive regulation of cell projection organization;GO:0043410//positive regulation of MAPK cascade;GO:0009653//anatomical structure morphogenesis;GO:0010586//miRNA metabolic process;GO:0007569//cell aging;GO:0016477//cell migration;GO:0012502//induction of programmed cell death;GO:0007254//JNK cascade;GO:0016601//Rac protein signal transduction;GO:0006935//chemotaxis;GO:0007599//hemostasis;GO:0006260//DNA replication;GO:0002376//immune system process;GO:0006366//transcription from RNA polymerase II promoter;GO:0007632//visual behavior;GO:0051259//protein oligomerization;GO:0016192//vesicle-mediated transport;GO:0038127//ERBB signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0048168//regulation of neuronal synaptic plasticity gi|55778655|gb|AAH86608.1|/5.04924e-99/Hras protein [Rattus norvegicus] 214425 4153 7.173333333 7.163333333 -0.002012595 Down 0.08221445 Cilp "cartilage intermediate layer protein, nucleotide pyrophosphohydrolase" K19031|1|6e-14|83.2|ola:105358350|cell migration-inducing and hyaluronan-binding protein [EC:3.2.1.35];K05141|5|6e-12|76.6|gja:107124770|tumor necrosis factor receptor superfamily member 1B GO:0044421;GO:0031012//extracellular matrix - GO:0009968//negative regulation of signal transduction gi|27734196|ref|NP_775561.1|/0/cartilage intermediate layer protein 1 precursor [Mus musculus] 67619 1647 15.76 15.77 0.000915125 Up 0.08221445 Nob1 NIN1/RPN12 binding protein 1 homolog K11883|1|0.0|761|mmu:67619|RNA-binding protein NOB1 GO:0043231//intracellular membrane-bounded organelle GO:0043169//cation binding - gi|30794454|ref|NP_080553.1|/0/RNA-binding protein NOB1 [Mus musculus] 27060 2753.11 5.4 5.39 -0.002674134 Down 0.08221445 Tcirg1 "T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3" K02154|1|0.0|1349|mmu:27060|V-type H+-transporting ATPase subunit a GO:0044459;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0044459;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0044459;GO:0016471//vacuolar proton-transporting V-type ATPase complex GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity;GO:0015077//monovalent inorganic cation transmembrane transporter activity "GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient;GO:0015988//energy coupled proton transmembrane transport, against electrochemical gradient" gi|209863008|ref|NP_001129563.1|/0/V-type proton ATPase 116 kDa subunit a isoform 3 [Mus musculus] 67655 3700 4.86 4.85 -0.002971567 Down 0.08221445 Ctdp1 "CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1" K15732|1|0.0|1709|mmu:67655|RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16] GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005819//spindle GO:0005488//binding;GO:0004722//protein serine/threonine phosphatase activity GO:0006464//cellular protein modification process;GO:0000087//mitotic M phase "gi|148677459|gb|EDL09406.1|/0/CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1, isoform CRA_c, partial [Mus musculus]" 68142 6296 3.236666667 3.23 -0.00297463 Down 0.08221445 Ino80 INO80 complex subunit K11665|1|0.0|2492|mmu:68142|DNA helicase INO80 [EC:3.6.4.12] - - - - 11479 3277 6.146666667 6.16 0.003126101 Up 0.08221445 Acvr1b "activin A receptor, type 1B" K13567|1|0.0|937|mmu:11479|activin receptor type-1B [EC:2.7.11.30] GO:0044464;GO:0016021//integral component of membrane GO:0017002//activin-activated receptor activity;GO:0032403//protein complex binding;GO:0032550;GO:0043169//cation binding;GO:0044389//ubiquitin-like protein ligase binding GO:0045137//development of primary sexual characteristics;GO:0043009//chordate embryonic development;GO:0032924//activin receptor signaling pathway;GO:0016049//cell growth;GO:0044772//mitotic cell cycle phase transition;GO:0008544//epidermis development;GO:0001934//positive regulation of protein phosphorylation;GO:0012502//induction of programmed cell death;GO:0007399//nervous system development;GO:0030335//positive regulation of cell migration;GO:0006366//transcription from RNA polymerase II promoter;GO:0030218//erythrocyte differentiation gi|6680630|ref|NP_031421.1|/0/activin receptor type-1B precursor [Mus musculus] 101240 2759 4.1 4.11 0.003514484 Up 0.08221445 Wdr91 WD repeat domain 91 K16482|1|1e-10|71.2|bfo:BRAFLDRAFT_205723|centriolar protein POC1;K12602|4|2e-08|63.9|xla:444484|WD repeat-containing protein 61 - - - - 238330 4112 16.86333333 16.85 -0.001141147 Down 0.08221445 Irf2bpl interferon regulatory factor 2 binding protein-like K04498|1|0.0|937|chx:102187824|E1A/CREB-binding protein [EC:2.3.1.48];K11318|2|9e-66|255|ocu:103350931|ataxin-7;K11412|4|1e-24|118|aam:106491452|NAD-dependent deacetylase sirtuin 2 [EC:3.5.1.-] - - - gi|50511149|dbj|BAD32560.1|/0/mKIAA1865 protein [Mus musculus] 67980 1867 4.176666667 4.186666667 0.00345005 Up 0.08221445 Gnpda2 glucosamine-6-phosphate deaminase 2 K02564|1|3e-161|571|mmu:67980|glucosamine-6-phosphate deaminase [EC:3.5.99.6] GO:0044424 GO:0003824//catalytic activity GO:0044238//primary metabolic process;GO:1901071 "gi|148705856|gb|EDL37803.1|/9.0889e-163/mCG10526, isoform CRA_b, partial [Mus musculus]" 68295 3447 9.413333333 9.42 0.001021377 Up 0.08221445 Aar2 AAR2 splicing factor homolog K13205|1|0.0|778|mmu:68295|A1 cistron-splicing factor AAR2 - - - - 108911 3790 6.67 6.66 -0.002164584 Down 0.08221445 Rcc2 regulator of chromosome condensation 2 K10615|1|3e-31|140|crg:105340402|E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26];K10614|5|3e-31|140|mze:106675917|E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26] GO:0044427;GO:0044444//cytoplasmic part;GO:0031981//nuclear lumen;GO:0015630//microtubule cytoskeleton - GO:0007067//mitotic nuclear division gi|33239431|ref|NP_776292.1|/0/protein RCC2 [Mus musculus] 58184 3285 6.593333333 6.583333333 -0.002189773 Down 0.08221445 Rqcd1 "CCR4-NOT transcription complex, subunit 9" K12606|1|3e-158|562|acs:100565877|CCR4-NOT transcription complex subunit 9 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0035770//ribonucleoprotein granule;GO:0044444//cytoplasmic part GO:0005488//binding "GO:0030520//intracellular estrogen receptor signaling pathway;GO:0044093;GO:0007166//cell surface receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0003006//developmental process involved in reproduction" gi|4885579|ref|NP_005435.1|/2.25382e-157/cell differentiation protein RCD1 homolog isoform 2 [Homo sapiens] 70310 2850.61 14.01333333 14.02333333 0.001029149 Up 0.08221445 Plscr3 phospholipid scramblase 3 K08885|1|6e-40|110|mmu:83813|non-receptor tyrosine-protein kinase TNK1 [EC:2.7.10.2] GO:0031224//intrinsic component of membrane;GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane;GO:0005740//mitochondrial envelope;GO:0031224//intrinsic component of membrane;GO:0005740//mitochondrial envelope GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0019904//protein domain specific binding;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0019904//protein domain specific binding;GO:0046872//metal ion binding;GO:0005548//phospholipid transporter activity;GO:0019904//protein domain specific binding GO:0012501//programmed cell death;GO:0055092//sterol homeostasis;GO:0007009//plasma membrane organization;GO:0032496//response to lipopolysaccharide;GO:0033500//carbohydrate homeostasis;GO:0012501//programmed cell death;GO:0055092//sterol homeostasis;GO:0007009//plasma membrane organization;GO:0032496//response to lipopolysaccharide;GO:0033500//carbohydrate homeostasis;GO:0012501//programmed cell death;GO:0055092//sterol homeostasis;GO:0007009//plasma membrane organization;GO:0032496//response to lipopolysaccharide;GO:0033500//carbohydrate homeostasis gi|74196739|dbj|BAE43107.1|/1.44028e-117/unnamed protein product [Mus musculus] 13169 2357 15.18333333 15.17333333 -0.000950496 Down 0.08221445 Dbnl drebrin-like K20520|1|0.0|709|mmu:13169|drebrin-like protein GO:0043232;GO:0031252//cell leading edge;GO:0044444//cytoplasmic part;GO:0044327//dendritic spine head;GO:0043232;GO:0031252//cell leading edge;GO:0044444//cytoplasmic part;GO:0044327//dendritic spine head;GO:0043232;GO:0031252//cell leading edge;GO:0044444//cytoplasmic part;GO:0044327//dendritic spine head GO:0003779//actin binding;GO:0003779//actin binding;GO:0003779//actin binding GO:0016192//vesicle-mediated transport;GO:0007265//Ras protein signal transduction;GO:0051693//actin filament capping;GO:0016192//vesicle-mediated transport;GO:0007265//Ras protein signal transduction;GO:0051693//actin filament capping;GO:0016192//vesicle-mediated transport;GO:0007265//Ras protein signal transduction;GO:0051693//actin filament capping "gi|148708608|gb|EDL40555.1|/0/drebrin-like, isoform CRA_b, partial [Mus musculus]" 622675 7625 4.446666667 4.44 -0.002164584 Down 0.08221445 Zfp827 zinc finger protein 827 K09228|1|5e-36|100|bfo:BRAFLDRAFT_250821|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|659928147|ref|NP_001281208.1|/0/zinc finger protein 827 isoform 2 [Mus musculus] 68564 10399 2.966666667 2.973333333 0.003238374 Up 0.08221445 Nufip2 nuclear fragile X mental retardation protein interacting protein 2 - GO:0005840//ribosome;GO:0043231//intracellular membrane-bounded organelle - - gi|28972720|dbj|BAC65776.1|/0/mKIAA1321 protein [Mus musculus] 22158 3401 5.59 5.603333333 0.003437036 Up 0.08221445 Tulp3 tubby-like protein 3 K19600|1|4e-117|425|cmy:102935323|tubby-related protein 1 GO:0005929//cilium;GO:0016020//membrane;GO:0005930//axoneme GO:0005543//phospholipid binding GO:0014020;GO:0007224//smoothened signaling pathway;GO:0043010//camera-type eye development;GO:0021513//spinal cord dorsal/ventral patterning;GO:0009887//organ morphogenesis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030326//embryonic limb morphogenesis gi|6755905|ref|NP_035787.1|/0/tubby-related protein 3 [Mus musculus] 19724 4179 9.633333333 9.62 -0.001998193 Down 0.08221445 Rfx1 "regulatory factor X, 1 (influences HLA class II expression)" K09173|1|0.0|1388|mmu:19724|regulatory factor X 1/2/3 - - "GO:0006351//transcription, DNA-templated" gi|239916007|ref|NP_033081.3|/0/MHC class II regulatory factor RFX1 [Mus musculus] 231225 3508 7.616666667 7.626666667 0.001892887 Up 0.08221445 Tapt1 transmembrane anterior posterior transformation 1 - GO:0031224//intrinsic component of membrane GO:0004930//G-protein coupled receptor activity GO:0043009//chordate embryonic development;GO:0001501//skeletal system development gi|71143116|ref|NP_776125.2|/0/transmembrane anterior posterior transformation protein 1 [Mus musculus] 67123 2715.81 22.33333333 22.34 0.000430591 Up 0.08221445 Ubap1 ubiquitin-associated protein 1 - - - - gi|26326367|dbj|BAC26927.1|/0/unnamed protein product [Mus musculus] 65102 2161 6.076666667 6.086666667 0.002372204 Up 0.08221445 Nif3l1 Ngg1 interacting factor 3-like 1 (S. pombe) - - - - - 76527 1758.49 5.783333333 5.77 -0.003329938 Down 0.08221445 Il34 interleukin 34 - GO:0044421;GO:0044421 GO:0005126//cytokine receptor binding;GO:0005126//cytokine receptor binding GO:0006952//defense response;GO:0008283//cell proliferation;GO:0001932//regulation of protein phosphorylation;GO:0006952//defense response;GO:0008283//cell proliferation;GO:0001932//regulation of protein phosphorylation "gi|148679522|gb|EDL11469.1|/4.72546e-158/RIKEN cDNA 2010004A03, isoform CRA_a, partial [Mus musculus]" 52892 4280 6.066666667 6.08 0.003167279 Up 0.08221445 Sco1 SCO1 cytochrome c oxidase assembly protein K07152|1|9e-138|494|mmu:52892|protein SCO1/2 GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding GO:0043623//cellular protein complex assembly;GO:0030003//cellular cation homeostasis;GO:0000041//transition metal ion transport gi|74228413|dbj|BAE24044.1|/7.74414e-137/unnamed protein product [Mus musculus] 66971 1970 5.986666667 5.976666667 -0.002411862 Down 0.08221445 Cdk5rap1 CDK5 regulatory subunit associated protein 1 K15865|1|1e-29|134|pxy:105385289|threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5] GO:0044424 GO:0043169//cation binding;GO:0051536//iron-sulfur cluster binding;GO:0019207//kinase regulator activity;GO:0005515//protein binding;GO:0003824//catalytic activity GO:0007417//central nervous system development;GO:0008033//tRNA processing;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0030182//neuron differentiation gi|13385358|ref|NP_080152.1|/0/CDK5 regulatory subunit-associated protein 1 [Mus musculus] 100044509 1075 3.816666667 3.806666667 -0.003784948 Down 0.08221445 Tgfbr3l "transforming growth factor, beta receptor III-like" "K05843|1|6e-19|97.4|cmy:102932544|transforming growth factor, beta receptor III" - - - gi|305410856|ref|NP_001182187.1|/8.89703e-89/transforming growth factor-beta receptor type 3-like protein precursor [Mus musculus] 22601 4185.3 20.36 20.35333333 -0.000472473 Down 0.08221445 Yap1 yes-associated protein 1 K16687|1|0.0|776|mmu:22601|transcriptional coactivator YAP1 GO:0031981//nuclear lumen;GO:0043234//protein complex;GO:0044444//cytoplasmic part;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0000975//regulatory region DNA binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0000975//regulatory region DNA binding GO:0003007//heart morphogenesis;GO:0042127//regulation of cell proliferation;GO:0048568//embryonic organ development;GO:0010332//response to gamma radiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0035265//organ growth;GO:0007498//mesoderm development;GO:0009913//epidermal cell differentiation;GO:0006915//apoptotic process;GO:0019827//stem cell population maintenance;GO:0030855//epithelial cell differentiation;GO:0033554//cellular response to stress;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030177//positive regulation of Wnt signaling pathway;GO:0035556//intracellular signal transduction;GO:0003007//heart morphogenesis;GO:0042127//regulation of cell proliferation;GO:0048568//embryonic organ development;GO:0010332//response to gamma radiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0035265//organ growth;GO:0007498//mesoderm development;GO:0009913//epidermal cell differentiation;GO:0006915//apoptotic process;GO:0019827//stem cell population maintenance;GO:0006468//protein phosphorylation;GO:0030855//epithelial cell differentiation;GO:0033554//cellular response to stress;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0030177//positive regulation of Wnt signaling pathway;GO:0035556//intracellular signal transduction gi|283945493|ref|NP_001164618.1|/0/transcriptional coactivator YAP1 isoform 1 [Mus musculus] 12211 15787 2.986666667 2.98 -0.003223901 Down 0.08221445 Birc6 baculoviral IAP repeat-containing 6 K10586|1|0.0|8539|mmu:12211|baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23] - - - gi|568998727|ref|XP_006523586.1|/0/PREDICTED: baculoviral IAP repeat-containing protein 6 isoform X6 [Mus musculus] 26443 997 92.37666667 92.36333333 -0.000208249 Down 0.08221445 Psma6 "proteasome (prosome, macropain) subunit, alpha type 6" K02730|1|9e-139|495|mmu:26443|20S proteasome subunit alpha 1 [EC:3.4.25.1] GO:0034399//nuclear periphery;GO:0005839//proteasome core complex;GO:0035770//ribonucleoprotein granule;GO:0030016//myofibril GO:0004175//endopeptidase activity;GO:0003676//nucleic acid binding;GO:0043168//anion binding;GO:0008134//transcription factor binding "GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044772//mitotic cell cycle phase transition;GO:0014706//striated muscle tissue development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006915//apoptotic process;GO:0044764;GO:0051320;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006520//cellular amino acid metabolic process;GO:0006954//inflammatory response;GO:0030330//DNA damage response, signal transduction by p53 class mediator" gi|890820674|ref|NP_001297512.1|/4.26633e-126/proteasome subunit alpha type-6 [Mus musculus] 78938 3072.56 5.41 5.42 0.002664258 Up 0.08221445 Fbxo34 F-box protein 34 K10311|1|0.0|1425|mmu:78938|F-box protein 34 - - - "gi|148688805|gb|EDL20752.1|/0/mCG113192, isoform CRA_b [Mus musculus]" 93895 2188 2.12 2.126666667 0.004529658 Up 0.08221445 Msx1os msh homeobox 1 opposite strand K09341|1|2e-48|196|pale:102888440|homeobox protein MSX GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle "GO:0005515//protein binding;GO:0003677//DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding" GO:0030326//embryonic limb morphogenesis;GO:0003272//endocardial cushion formation;GO:0001501//skeletal system development;GO:0007420//brain development;GO:0043009//chordate embryonic development;GO:0043392//negative regulation of DNA binding;GO:0033365//protein localization to organelle;GO:0016049//cell growth;GO:0042471//ear morphogenesis;GO:0042476//odontogenesis;GO:0000904//cell morphogenesis involved in differentiation;GO:0030509//BMP signaling pathway;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0051146//striated muscle cell differentiation;GO:0008283//cell proliferation;GO:0003002//regionalization;GO:0030879//mammary gland development;GO:0031647//regulation of protein stability;GO:0035878//nail development gi|9247217|gb|AAB31962.2|/8.71815e-71/homeobox protein [Mus sp.] 17222 8967 5.666666667 5.66 -0.001698287 Down 0.08221445 Anapc1 anaphase promoting complex subunit 1 K03348|1|0.0|3780|mmu:17222|anaphase-promoting complex subunit 1 GO:0031981//nuclear lumen;GO:0000152//nuclear ubiquitin ligase complex;GO:0044444//cytoplasmic part - GO:0000209//protein polyubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045841//negative regulation of mitotic metaphase/anaphase transition;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle gi|228008323|ref|NP_032595.2|/0/anaphase-promoting complex subunit 1 [Mus musculus] 66220 1152 2.906666667 2.896666667 -0.004971958 Down 0.08221445 Zdhhc12 "zinc finger, DHHC domain containing 12" K18932|1|7e-77|290|mmu:66220|palmitoyltransferase [EC:2.3.1.225] - - - gi|83649755|ref|NP_079704.2|/1.78103e-88/probable palmitoyltransferase ZDHHC12 isoform a [Mus musculus] 56706 2161 6.963333333 6.976666667 0.002759819 Up 0.08221445 Ccnl1 cyclin L1 K15188|1|7e-21|105|cmk:103180382|cyclin T GO:0016604//nuclear body GO:0005515//protein binding "GO:0050794//regulation of cellular process;GO:0006351//transcription, DNA-templated" "gi|148683588|gb|EDL15535.1|/0/mCG8564, isoform CRA_b, partial [Mus musculus]" 74347 2574 8.146666667 8.14 -0.001181085 Down 0.08221445 Tldc1 TBC/LysM associated domain containing 1 K12587|1|2e-08|63.9|bfo:BRAFLDRAFT_124886|exosome complex component MTR3 - - - gi|28077021|ref|NP_083159.1|/0/TLD domain-containing protein 1 [Mus musculus] 53618 2572.17 9.883333333 9.873333333 -0.001460464 Down 0.08221445 Fut8 fucosyltransferase 8 K00717|1|0.0|793|mmu:53618|glycoprotein 6-alpha-L-fucosyltransferase [EC:2.4.1.68] GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane GO:0046921//alpha-(1->6)-fucosyltransferase activity;GO:0019904//protein domain specific binding;GO:0046921//alpha-(1->6)-fucosyltransferase activity;GO:0019904//protein domain specific binding;GO:0046921//alpha-(1->6)-fucosyltransferase activity;GO:0019904//protein domain specific binding;GO:0046921//alpha-(1->6)-fucosyltransferase activity;GO:0019904//protein domain specific binding;GO:0046921//alpha-(1->6)-fucosyltransferase activity;GO:0019904//protein domain specific binding GO:0048870//cell motility;GO:0006486//protein glycosylation;GO:0036065//fucosylation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0044707;GO:0048870//cell motility;GO:0006486//protein glycosylation;GO:0036065//fucosylation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0044707;GO:0048870//cell motility;GO:0006486//protein glycosylation;GO:0036065//fucosylation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0044707;GO:0048870//cell motility;GO:0006486//protein glycosylation;GO:0036065//fucosylation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0044707;GO:0048870//cell motility;GO:0006486//protein glycosylation;GO:0036065//fucosylation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0044707 "gi|148704495|gb|EDL36442.1|/0/fucosyltransferase 8, isoform CRA_b, partial [Mus musculus]" 26441 1096 63.70333333 63.69 -0.000301993 Down 0.08221445 Psma4 "proteasome (prosome, macropain) subunit, alpha type 4" K02728|1|6e-122|439|pale:102878197|20S proteasome subunit alpha 3 [EC:3.4.25.1] GO:0005839//proteasome core complex;GO:0043231//intracellular membrane-bounded organelle GO:0004175//endopeptidase activity GO:0019941//modification-dependent protein catabolic process gi|987952702|ref|XP_015421661.1|/5.33602e-121/PREDICTED: proteasome subunit alpha type-4 [Myotis davidii] 83814 8163 3.746666667 3.756666667 0.00384548 Up 0.08221445 Nedd4l "neural precursor cell expressed, developmentally down-regulated gene 4-like" K13305|1|0.0|1738|mmu:83814|E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26] GO:0044464;GO:0031981//nuclear lumen;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0008200//ion channel inhibitor activity;GO:0019787//ubiquitin-like protein transferase activity;GO:0008200//ion channel inhibitor activity;GO:0005488//binding GO:0070830//bicellular tight junction assembly;GO:0010035//response to inorganic substance;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0009896;GO:0002028//regulation of sodium ion transport;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:0006970//response to osmotic stress;GO:0016567//protein ubiquitination;GO:0006873//cellular ion homeostasis;GO:0006366//transcription from RNA polymerase II promoter;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0003073//regulation of systemic arterial blood pressure;GO:0009894;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006970//response to osmotic stress;GO:0006897//endocytosis;GO:0070830//bicellular tight junction assembly;GO:0010035//response to inorganic substance;GO:0032446//protein modification by small protein conjugation;GO:0002028//regulation of sodium ion transport;GO:0006875//cellular metal ion homeostasis "gi|148677748|gb|EDL09695.1|/0/neural precursor cell expressed, developmentally down-regulated gene 4-like, isoform CRA_b [Mus musculus]" 22691 2302 4.526666667 4.516666667 -0.003190628 Down 0.08221445 Zscan2 zinc finger and SCAN domain containing 2 K09230|1|0.0|1273|mmu:22691|SCAN domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0048869//cellular developmental process;GO:0044764;GO:0048232//male gamete generation;GO:0006351//transcription, DNA-templated" gi|6677607|ref|NP_033579.1|/0/zinc finger and SCAN domain-containing protein 2 [Mus musculus] 170756 2780.71 5.76 5.75 -0.002506856 Down 0.08221445 Slc8b1 "solute carrier family 8 (sodium/lithium/calcium exchanger), member B1" "K13754|1|0.0|819|mmu:170756|solute carrier family 24 (sodium/potassium/calcium exchanger), member 6" GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031301//integral component of organelle membrane;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031301//integral component of organelle membrane;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0031301//integral component of organelle membrane;GO:0005886//plasma membrane GO:0015081//sodium ion transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0015081//sodium ion transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0015081//sodium ion transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0006814//sodium ion transport;GO:0006816//calcium ion transport;GO:0030073//insulin secretion;GO:0033500//carbohydrate homeostasis;GO:0006814//sodium ion transport;GO:0006816//calcium ion transport;GO:0030073//insulin secretion;GO:0033500//carbohydrate homeostasis;GO:0006814//sodium ion transport;GO:0006816//calcium ion transport;GO:0030073//insulin secretion;GO:0033500//carbohydrate homeostasis "gi|170650649|ref|NP_573484.2|/0/sodium/potassium/calcium exchanger 6, mitochondrial isoform 1 precursor [Mus musculus]" 80913 5952.52 12.37666667 12.36333333 -0.001555047 Down 0.08221445 Pum2 pumilio RNA-binding family member 2 K17943|1|0.0|1583|mmu:80913|pumilio RNA-binding family GO:0043005//neuron projection;GO:0044444//cytoplasmic part;GO:0035770//ribonucleoprotein granule;GO:0044297//cell body;GO:0043005//neuron projection;GO:0044444//cytoplasmic part;GO:0035770//ribonucleoprotein granule;GO:0044297//cell body GO:0005488//binding;GO:0005488//binding GO:0006412//translation;GO:0022618//ribonucleoprotein complex assembly;GO:0006412//translation;GO:0022618//ribonucleoprotein complex assembly gi|887214451|ref|NP_001297448.1|/0/pumilio homolog 2 isoform 4 [Mus musculus] 66398 998 6.503333333 6.49 -0.002960894 Down 0.08221445 Commd5 COMM domain containing 5 K09228|1|2e-88|328|ngi:103735297|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle - GO:0022402//cell cycle process;GO:0030154//cell differentiation "gi|148697676|gb|EDL29623.1|/1.62488e-126/COMM domain containing 5, isoform CRA_a, partial [Mus musculus]" 68550 1302 9.75 9.756666667 0.000986121 Up 0.08221445 Tefm "transcription elongation factor, mitochondrial" "K17658|1|0.0|724|mmu:68550|transcription elongation factor, mitochondrial" GO:0032991//macromolecular complex;GO:0005759//mitochondrial matrix "GO:0030234//enzyme regulator activity;GO:0016889//endodeoxyribonuclease activity, producing 3'-phosphomonoesters" "GO:0000959//mitochondrial RNA metabolic process;GO:0019222//regulation of metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006261//DNA-dependent DNA replication;GO:0006351//transcription, DNA-templated" "gi|134053922|ref|NP_899098.2|/0/transcription elongation factor, mitochondrial [Mus musculus]" 78656 4632.37 5.22 5.206666667 -0.003689759 Down 0.08221445 Brd8 bromodomain containing 8 K11321|1|0.0|1468|umr:103663790|bromodomain-containing protein 8 - - - gi|185134208|ref|NP_084423.2|/0/bromodomain-containing protein 8 isoform 1 [Mus musculus] 80884 2103 7.573333333 7.563333333 -0.001906226 Down 0.08221445 Maged2 "melanoma antigen, family D, 2" K12464|1|4e-90|335|cge:100768434|melanoma-associated antigen D1 - - - gi|12659136|gb|AAK01204.1|/0/mage-d2 [Mus musculus] 235132 8882 2.85 2.853333333 0.001686377 Up 0.080089511 Zbtb44 zinc finger and BTB domain containing 44 K10515|1|0.0|829|mmu:235132|zinc finger and BTB domain-containing protein 44 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" "gi|148693388|gb|EDL25335.1|/0/BTB (POZ) domain containing 15, isoform CRA_a, partial [Mus musculus]" 320297 2807 0.023333333 0.023333333 0 - 0.080089511 A830009L08Rik RIKEN cDNA A830009L08 gene - - - - - 328963 3083 0.033333333 0.036666667 0.137503524 Up 0.080089511 G630071F17Rik RIKEN cDNA G630071F17 gene - - - - - 217138 1410 0.04 0.04 0 - 0.080089511 Prr15l proline rich 15-like K02864|1|2e-21|106|mze:101483881|large subunit ribosomal protein L10 - - - gi|26352600|dbj|BAC39930.1|/6.52631e-80/unnamed protein product [Mus musculus] 71373 2224 0.03 0.026666667 -0.169925001 Down 0.080089511 Prr16 proline rich 16 - - - - gi|124487027|ref|NP_001074693.1|/7.40776e-114/protein Largen [Mus musculus] 100041062 549 0.01 0.013333333 0.415037499 Up 0.080089511 Gm13286 predicted gene 13286 K05414|1|1e-36|154|cge:100763520|interferon alpha GO:0044421 GO:0005102//receptor binding GO:0007166//cell surface receptor signaling pathway;GO:0030098//lymphocyte differentiation;GO:0002252;GO:0007049//cell cycle;GO:0012501//programmed cell death gi|341926237|ref|NP_001230079.1|/5.95996e-100/interferon zeta-like precursor [Mus musculus] 239611 22806 0.01 0.01 0 - 0.080089511 Muc19 mucin 19 K10955|1|0.0|951|cmk:103189554|intestinal mucin-2;K13908|5|0.0|839|clv:102093782|mucin-5B GO:0044431//Golgi apparatus part - GO:0006493//protein O-linked glycosylation gi|48374047|ref|NP_997126.2|/0/mucin-19 precursor [Mus musculus] 227059 5003 1.48 1.476666667 -0.003252978 Down 0.080089511 Slc39a10 "solute carrier family 39 (zinc transporter), member 10" "K14716|1|0.0|1384|mmu:227059|solute carrier family 39 (zinc transporter), member 10" GO:0031224//intrinsic component of membrane GO:0008324//cation transmembrane transporter activity GO:0000041//transition metal ion transport;GO:0044763 gi|568906264|ref|XP_006495995.1|/0/PREDICTED: zinc transporter ZIP10 isoform X2 [Mus musculus] 100504350 2543 0.026666667 0.023333333 -0.192645078 Down 0.080089511 Gm14169 predicted gene 14169 - - - - - 110789 19328 0.01 0.013333333 0.415037499 Up 0.080089511 Adgrv1 adhesion G protein-coupled receptor V1 K18263|1|0.0|1.218e+04|mmu:110789|G-protein coupled receptor 98 - - - - 18491 11027 0.033333333 0.033333333 0 - 0.080089511 Pappa pregnancy-associated plasma protein A K07762|1|0.0|3240|mmu:18491|pappalysin-1 [EC:3.4.24.79] - - - - 16772 9518 0.01 0.013333333 0.415037499 Up 0.080089511 Lama1 "laminin, alpha 1" "K05637|1|0.0|6084|mmu:16772|laminin, alpha 1/2" GO:0030054//cell junction;GO:0043256//laminin complex GO:0046625//sphingolipid binding;GO:0005515//protein binding;GO:0005198//structural molecule activity GO:0016477//cell migration;GO:0048514//blood vessel morphogenesis;GO:0043010//camera-type eye development;GO:0030030//cell projection organization;GO:0007435//salivary gland morphogenesis;GO:0048754//branching morphogenesis of an epithelial tube;GO:0030859//polarized epithelial cell differentiation;GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0009790//embryo development gi|117168301|ref|NP_032506.2|/0/laminin subunit alpha-1 precursor [Mus musculus] 330599 3050 0.16 0.16 0 - 0.080089511 Gm16938 "predicted gene, 16938" - - - - - 76571 1667 0.153333333 0.153333333 -3.20E-16 Down 0.080089511 Styxl1 serine/threonine/tyrosine interacting-like 1 K18047|1|4e-166|587|mmu:76571|serine/threonine/tyrosine-interacting-like protein 1 - GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004721//phosphoprotein phosphatase activity GO:0007165//signal transduction "gi|148687405|gb|EDL19352.1|/5.24972e-167/serine/threonine/tyrosine interacting-like 1, isoform CRA_a, partial [Mus musculus]" 74970 1030 0.053333333 0.05 -0.093109404 Down 0.080089511 4930483O08Rik RIKEN cDNA 4930483O08 gene - - - - "gi|148685815|gb|EDL17762.1|/2.01289e-42/mCG144662, partial [Mus musculus]" 94217 14743 0.01 0.01 0 - 0.080089511 Lrp1b low density lipoprotein-related protein 1B (deleted in tumors) K20049|1|0.0|9362|mmu:94217|low-density lipoprotein receptor-related protein 1B GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding;GO:0030228//lipoprotein particle receptor activity GO:0006897//endocytosis;GO:0045184//establishment of protein localization gi|568914579|ref|XP_006498522.1|/0/PREDICTED: low-density lipoprotein receptor-related protein 1B isoform X1 [Mus musculus] 211961 11697 0.016666667 0.016666667 0 - 0.080089511 Asxl3 additional sex combs like 3 (Drosophila) K11471|1|0.0|3927|mmu:211961|additional sex combs-like protein - - - gi|569003464|ref|XP_006525804.1|/0/PREDICTED: putative Polycomb group protein ASXL3 isoform X4 [Mus musculus] 245671 4457 0.03 0.026666667 -0.169925001 Down 0.080089511 Klf8 Kruppel-like factor 8 K09205|1|0.0|650|mmu:245671|krueppel-like factor 8/12 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|569012000|ref|XP_006528915.1|/0/PREDICTED: Krueppel-like factor 8 isoform X2 [Mus musculus] 78229 460 0.12 0.12 0 - 0.080089511 4930596I21Rik RIKEN cDNA 4930596I21 gene - - - - "gi|148707587|gb|EDL39534.1|/2.78844e-21/mCG1047697, partial [Mus musculus]" 319781 4414 0.016666667 0.016666667 0 - 0.080089511 9530051G07Rik RIKEN cDNA 9530051G07 gene - - - - "gi|148699413|gb|EDL31360.1|/2.37747e-56/mCG144811, partial [Mus musculus]" 18198 3330 0.033333333 0.036666667 0.137503524 Up 0.080089511 Musk "muscle, skeletal, receptor tyrosine kinase" "K05129|1|0.0|917|mmu:18198|muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]" GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0097060//synaptic membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0097060//synaptic membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0097060//synaptic membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0097060//synaptic membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0097060//synaptic membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0097060//synaptic membrane GO:0004713//protein tyrosine kinase activity;GO:0019900//kinase binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0004713//protein tyrosine kinase activity;GO:0019900//kinase binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0004713//protein tyrosine kinase activity;GO:0019900//kinase binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0004713//protein tyrosine kinase activity;GO:0019900//kinase binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0004713//protein tyrosine kinase activity;GO:0019900//kinase binding;GO:0032550;GO:0019904//protein domain specific binding;GO:0004713//protein tyrosine kinase activity;GO:0019900//kinase binding;GO:0032550;GO:0019904//protein domain specific binding "GO:0043065//positive regulation of apoptotic process;GO:0001941//postsynaptic membrane organization;GO:0009628//response to abiotic stimulus;GO:0048167//regulation of synaptic plasticity;GO:0006351//transcription, DNA-templated;GO:0072657//protein localization to membrane;GO:0007611//learning or memory;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0007271//synaptic transmission, cholinergic;GO:0001934//positive regulation of protein phosphorylation;GO:0018344//protein geranylgeranylation;GO:0014823//response to activity;GO:0043010//camera-type eye development;GO:0009611//response to wounding;GO:0043065//positive regulation of apoptotic process;GO:0001941//postsynaptic membrane organization;GO:0009628//response to abiotic stimulus;GO:0048167//regulation of synaptic plasticity;GO:0006351//transcription, DNA-templated;GO:0072657//protein localization to membrane;GO:0007611//learning or memory;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0007271//synaptic transmission, cholinergic;GO:0001934//positive regulation of protein phosphorylation;GO:0018344//protein geranylgeranylation;GO:0014823//response to activity;GO:0043010//camera-type eye development;GO:0009611//response to wounding;GO:0043065//positive regulation of apoptotic process;GO:0001941//postsynaptic membrane organization;GO:0009628//response to abiotic stimulus;GO:0048167//regulation of synaptic plasticity;GO:0006351//transcription, DNA-templated;GO:0072657//protein localization to membrane;GO:0007611//learning or memory;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0007271//synaptic transmission, cholinergic;GO:0001934//positive regulation of protein phosphorylation;GO:0018344//protein geranylgeranylation;GO:0014823//response to activity;GO:0043010//camera-type eye development;GO:0009611//response to wounding;GO:0043065//positive regulation of apoptotic process;GO:0001941//postsynaptic membrane organization;GO:0009628//response to abiotic stimulus;GO:0048167//regulation of synaptic plasticity;GO:0006351//transcription, DNA-templated;GO:0072657//protein localization to membrane;GO:0007611//learning or memory;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0007271//synaptic transmission, cholinergic;GO:0001934//positive regulation of protein phosphorylation;GO:0018344//protein geranylgeranylation;GO:0014823//response to activity;GO:0043010//camera-type eye development;GO:0009611//response to wounding;GO:0043065//positive regulation of apoptotic process;GO:0001941//postsynaptic membrane organization;GO:0009628//response to abiotic stimulus;GO:0048167//regulation of synaptic plasticity;GO:0006351//transcription, DNA-templated;GO:0072657//protein localization to membrane;GO:0007611//learning or memory;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0007271//synaptic transmission, cholinergic;GO:0001934//positive regulation of protein phosphorylation;GO:0018344//protein geranylgeranylation;GO:0014823//response to activity;GO:0043010//camera-type eye development;GO:0009611//response to wounding;GO:0043065//positive regulation of apoptotic process;GO:0001941//postsynaptic membrane organization;GO:0009628//response to abiotic stimulus;GO:0048167//regulation of synaptic plasticity;GO:0006351//transcription, DNA-templated;GO:0072657//protein localization to membrane;GO:0007611//learning or memory;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0007271//synaptic transmission, cholinergic;GO:0001934//positive regulation of protein phosphorylation;GO:0018344//protein geranylgeranylation;GO:0014823//response to activity;GO:0043010//camera-type eye development;GO:0009611//response to wounding" "gi|82533049|ref|NP_001032207.1|/0/muscle, skeletal receptor tyrosine-protein kinase isoform 5 [Mus musculus]" 239096 2728 0.13 0.126666667 -0.037474705 Down 0.080089511 Cdh24 cadherin-like 24 K06814|1|0.0|1319|mmu:239096|cadherin-like 24 GO:0031224//intrinsic component of membrane;GO:0030054//cell junction GO:0046872//metal ion binding;GO:0005515//protein binding GO:0016337//single organismal cell-cell adhesion gi|41054976|ref|NP_955764.1|/0/cadherin-24 precursor [Mus musculus] 269275 8666 0.01 0.013333333 0.415037499 Up 0.080089511 Acvr1c "activin A receptor, type IC" K13568|1|0.0|958|mmu:269275|activin receptor type-1C [EC:2.7.11.30] GO:0005887//integral component of plasma membrane;GO:0044424;GO:0005887//integral component of plasma membrane GO:0032550;GO:0005515//protein binding;GO:0043169//cation binding;GO:0017002//activin-activated receptor activity;GO:0032550;GO:0070696//transmembrane receptor protein serine/threonine kinase binding;GO:0043169//cation binding;GO:0017002//activin-activated receptor activity;GO:0032403//protein complex binding GO:0030336//negative regulation of cell migration;GO:0006915//apoptotic process;GO:0050796//regulation of insulin secretion;GO:0008285//negative regulation of cell proliferation;GO:0043434//response to peptide hormone;GO:0048869//cellular developmental process;GO:0006464//cellular protein modification process;GO:0009746;GO:0040014//regulation of multicellular organism growth;GO:0010876//lipid localization;GO:0032924//activin receptor signaling pathway;GO:0030336//negative regulation of cell migration;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006915//apoptotic process;GO:0050796//regulation of insulin secretion;GO:0009855//determination of bilateral symmetry;GO:0006796//phosphate-containing compound metabolic process;GO:0008285//negative regulation of cell proliferation;GO:0021543//pallium development;GO:0043434//response to peptide hormone;GO:0048869//cellular developmental process;GO:0006464//cellular protein modification process;GO:0009746;GO:0022037//metencephalon development;GO:0001832//blastocyst growth;GO:0040014//regulation of multicellular organism growth;GO:0010876//lipid localization;GO:0032924//activin receptor signaling pathway gi|568913788|ref|XP_006498149.1|/0/PREDICTED: activin receptor type-1C isoform X2 [Mus musculus] 242425 3998 0.02 0.02 0 - 0.080089511 Gabbr2 "gamma-aminobutyric acid (GABA) B receptor, 2" K04615|1|0.0|1726|mmu:242425|gamma-aminobutyric acid type B receptor GO:0097060//synaptic membrane;GO:0016021//integral component of membrane;GO:0044424;GO:0042995//cell projection GO:0004930//G-protein coupled receptor activity GO:0007186//G-protein coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0030818//negative regulation of cAMP biosynthetic process gi|589921623|ref|XP_006973743.1|/0/PREDICTED: gamma-aminobutyric acid type B receptor subunit 2 [Peromyscus maniculatus bairdii] 66797 7002 0.013333333 0.01 -0.415037499 Down 0.080089511 Cntnap2 contactin associated protein-like 2 K07380|1|4e-89|332|mmu:66797|contactin associated protein-like 2 GO:0043231//intracellular membrane-bounded organelle;GO:0033267;GO:0032589//neuron projection membrane;GO:0005887//integral component of plasma membrane GO:0005515//protein binding GO:0022610;GO:0030030//cell projection organization;GO:0021987//cerebral cortex development;GO:0021544//subpallium development;GO:0034613//cellular protein localization;GO:0021536//diencephalon development;GO:0044704//single-organism reproductive behavior gi|37360128|dbj|BAC98042.1|/0/mKIAA0868 protein [Mus musculus] 23850 8602 0.016666667 0.013333333 -0.321928095 Down 0.080089511 Pappa2 pappalysin 2 K08647|1|0.0|3719|mmu:23850|pappalysin-2 [EC:3.4.24.-] - - - gi|145699121|ref|NP_001078845.1|/0/pappalysin-2 precursor [Mus musculus] 320363 1892 0.033333333 0.033333333 0 - 0.080089511 D030045P18Rik RIKEN cDNA D030045P18 gene - - - - - 69206 1558 0.036666667 0.036666667 0 - 0.080089511 2010016I18Rik RIKEN cDNA 2010016I18 gene - - - - gi|74150076|dbj|BAE24354.1|/1.03578e-36/unnamed protein product [Mus musculus] 70357 2005 0.146666667 0.146666667 0 - 0.080089511 Kcnip1 Kv channel-interacting protein 1 K16575|1|5e-76|288|aam:106493806|centractin;K19932|2|1e-43|181|aqu:100635568|neuronal calcium sensor 1 GO:0043005//neuron projection;GO:0044297//cell body;GO:0034703//cation channel complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0034703//cation channel complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0034703//cation channel complex;GO:0043005//neuron projection;GO:0044297//cell body;GO:0034703//cation channel complex GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0016247//channel regulator activity;GO:0005261//cation channel activity;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0016247//channel regulator activity;GO:0005261//cation channel activity;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0016247//channel regulator activity;GO:0005261//cation channel activity;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity;GO:0016247//channel regulator activity;GO:0005261//cation channel activity GO:0001508//action potential;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0001508//action potential;GO:0007267//cell-cell signaling;GO:0009593//detection of chemical stimulus;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0001508//action potential;GO:0007267//cell-cell signaling;GO:0009593//detection of chemical stimulus;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0001508//action potential;GO:0007267//cell-cell signaling;GO:0009593//detection of chemical stimulus;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|676280256|gb|KFO34145.1|/3.23739e-113/Kv channel-interacting protein 1 [Fukomys damarensis] 279561 10259 0.01 0.01 0 - 0.080089511 Wnk3 WNK lysine deficient protein kinase 3 K08867|1|0.0|3160|mmu:279561|WNK lysine deficient protein kinase [EC:2.7.11.1] - - - - 13417 14583 0.023333333 0.026666667 0.192645078 Up 0.080089511 Dnah8 "dynein, axonemal, heavy chain 8" "K10408|1|0.0|9061|mmu:13417|dynein heavy chain, axonemal" - - - "gi|153792273|ref|NP_038839.2|/0/dynein heavy chain 8, axonemal [Mus musculus]" 237868 5044 0.06 0.063333333 0.078002512 Up 0.080089511 Sarm1 sterile alpha and HEAT/Armadillo motif containing 1 - GO:0015630//microtubule cytoskeleton;GO:0005741//mitochondrial outer membrane;GO:0015630//microtubule cytoskeleton;GO:0005741//mitochondrial outer membrane - GO:0006952//defense response;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0009746;GO:0006915//apoptotic process;GO:0007154//cell communication;GO:0006952//defense response;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0009746;GO:0006915//apoptotic process;GO:0007154//cell communication gi|50510513|dbj|BAD32242.1|/0/mKIAA0524 protein [Mus musculus] 14171 1687 0.036666667 0.033333333 -0.137503524 Down 0.080089511 Fgf17 fibroblast growth factor 17 K04358|1|1e-109|384|fca:101090606|fibroblast growth factor GO:0044421 GO:0005104//fibroblast growth factor receptor binding GO:0048731//system development;GO:0008283//cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway gi|586983375|ref|XP_003984765.2|/8.62234e-109/PREDICTED: fibroblast growth factor 17 isoform X1 [Felis catus] 56318 2667 0.026666667 0.023333333 -0.192645078 Down 0.080089511 Acpp "acid phosphatase, prostate" K19283|1|0.0|689|mmu:56318|prostatic aicd phosphatase [EC:3.1.3.2 3.1.3.5] "GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0005795//Golgi stack;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005770//late endosome;GO:0042995//cell projection;GO:0031224//intrinsic component of membrane;GO:0005764//lysosome;GO:0005795//Golgi stack;GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0005770//late endosome;GO:0042995//cell projection" GO:0043169//cation binding;GO:0042802//identical protein binding;GO:0008252//nucleotidase activity;GO:0043169//cation binding;GO:0042802//identical protein binding;GO:0008252//nucleotidase activity GO:0046128;GO:0006753//nucleoside phosphate metabolic process;GO:0009112;GO:0046128;GO:0006753//nucleoside phosphate metabolic process;GO:0009112 "gi|148689143|gb|EDL21090.1|/0/acid phosphatase, prostate, isoform CRA_b, partial [Mus musculus]" 100764 1620.31 7.076666667 7.076666667 -1.60E-16 Down 0.080089511 Rita1 RBPJ interacting and tubulin associated 1 - GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle;GO:0005815//microtubule organizing center;GO:0043231//intracellular membrane-bounded organelle GO:0008092//cytoskeletal protein binding;GO:0008092//cytoskeletal protein binding GO:0006913//nucleocytoplasmic transport;GO:0007219//Notch signaling pathway;GO:0007399//nervous system development;GO:0006913//nucleocytoplasmic transport;GO:0007219//Notch signaling pathway;GO:0007399//nervous system development "gi|148687813|gb|EDL19760.1|/6.2446e-144/RIKEN cDNA 1110008J03, isoform CRA_a, partial [Mus musculus]" 241489 2848 0.036666667 0.04 0.125530882 Up 0.080089511 Pde11a phosphodiesterase 11A "K13298|1|0.0|1792|mmu:241489|dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]" GO:0044444//cytoplasmic part;GO:0043025//neuronal cell body "GO:0043169//cation binding;GO:0030551//cyclic nucleotide binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity" GO:0009154//purine ribonucleotide catabolic process;GO:0007599//hemostasis;GO:0046058//cAMP metabolic process;GO:0007154//cell communication "gi|124486646|ref|NP_001074502.1|/0/dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [Mus musculus]" 225997 6520 0.013333333 0.013333333 0 - 0.080089511 Trpm6 "transient receptor potential cation channel, subfamily M, member 6" K04981|1|0.0|3865|mmu:225997|transient receptor potential cation channel subfamily M member 6 [EC:2.7.11.1] GO:0031224//intrinsic component of membrane;GO:0005903//brush border;GO:0044459 GO:0043169//cation binding;GO:0032550;GO:0004672//protein kinase activity;GO:0005261//cation channel activity GO:0044763;GO:0006464//cellular protein modification process;GO:0042221//response to chemical;GO:0006816//calcium ion transport;GO:0006796//phosphate-containing compound metabolic process gi|23510305|ref|NP_700466.1|/0/transient receptor potential cation channel subfamily M member 6 [Mus musculus] 16470 3183 0.11 0.113333333 0.043068722 Up 0.080089511 Ush1g Usher syndrome 1G K12460|1|1e-13|81.6|mdo:100032130|ankyrin repeat-rich membrane spanning protein;K15502|4|6e-13|79.3|spu:755512|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A GO:0005856//cytoskeleton;GO:0016020//membrane GO:0042802//identical protein binding GO:0042471//ear morphogenesis;GO:0050954//sensory perception of mechanical stimulus;GO:0007601//visual perception;GO:0042490//mechanoreceptor differentiation gi|28436077|dbj|BAC57426.1|/0/Jackson shaker [Mus musculus] 13839 7789 0.013333333 0.01 -0.415037499 Down 0.080089511 Epha5 Eph receptor A5 K05106|1|0.0|1651|mmu:13839|Eph receptor A5 [EC:2.7.10.1] - - - - 84653 964 0.106666667 0.103333333 -0.04580369 Down 0.080089511 Hes7 hairy and enhancer of split 7 (Drosophila) K09087|1|3e-91|337|mmu:84653|hairy and enhancer of split 2/6/7 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding;GO:0005515//protein binding "GO:0048731//system development;GO:0009888//tissue development;GO:0009952//anterior/posterior pattern specification;GO:0007166//cell surface receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis" gi|61098129|ref|NP_149030.2|/2.30882e-90/transcription factor HES-7 [Mus musculus] 16876 4551 0.053333333 0.05 -0.093109404 Down 0.080089511 Lhx9 LIM homeobox protein 9 K09373|1|0.0|648|cfa:490257|LIM homeobox protein 2/9 GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0006351//transcription, DNA-templated;GO:0008406//gonad development;GO:0007411//axon guidance;GO:0006351//transcription, DNA-templated;GO:0008406//gonad development;GO:0006351//transcription, DNA-templated;GO:0008406//gonad development" gi|110611159|ref|NP_001036042.1|/0/LIM/homeobox protein Lhx9 isoform c [Mus musculus] 75305 1737 0.033333333 0.03 -0.152003093 Down 0.080089511 Ankrd53 ankyrin repeat domain 53 K15503|1|1e-14|84.0|aag:AaeL_AAEL014668|serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B - - - gi|268370084|ref|NP_083521.2|/0/ankyrin repeat domain-containing protein 53 [Mus musculus] 74734 4960 0.143333333 0.143333333 0 - 0.080089511 Rhoh ras homolog family member H "K07873|1|2e-104|384|mmu:74734|Ras homolog gene family, member H" GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0044444//cytoplasmic part GO:0032550;GO:0017016//Ras GTPase binding;GO:0004857//enzyme inhibitor activity "GO:0006351//transcription, DNA-templated;GO:0002274;GO:0016310//phosphorylation;GO:0007264//small GTPase mediated signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0044092//negative regulation of molecular function;GO:0030098//lymphocyte differentiation" gi|124487389|ref|NP_001074574.1|/1.73138e-103/rho-related GTP-binding protein RhoH precursor [Mus musculus] 76843 4221 0.07 0.07 0 - 0.080089511 Dtl denticleless E3 ubiquitin protein ligase K11790|1|0.0|1274|rno:305073|denticleless - - - "gi|148681042|gb|EDL12989.1|/0/denticleless homolog (Drosophila), isoform CRA_b, partial [Mus musculus]" 20755 3547 0.02 0.023333333 0.222392421 Up 0.080089511 Sprr2a1 small proline-rich protein 2A1 K02889|1|2e-41|87.0|oas:101115288|large subunit ribosomal protein L21e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression "gi|148704804|gb|EDL36751.1|/2.02759e-41/mCG12076, partial [Mus musculus]" 13011 986 0.06 0.056666667 -0.08246216 Down 0.080089511 Cst7 cystatin F (leukocystatin) K13903|1|2e-79|298|mmu:13011|cystatin-F - GO:0004866//endopeptidase inhibitor activity GO:0051346//negative regulation of hydrolase activity gi|3986155|dbj|BAA34940.1|/5.51803e-95/murine CMAP [Mus musculus] 50528 3175 0.023333333 0.02 -0.222392421 Down 0.080089511 Tmprss2 "transmembrane protease, serine 2" K09633|1|0.0|972|mmu:50528|transmembrane protease serine 2 [EC:3.4.21.-] GO:0044424;GO:0031224//intrinsic component of membrane GO:0038024//cargo receptor activity;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|34328226|ref|NP_056590.2|/0/transmembrane protease serine 2 [Mus musculus] 100503197 2624 0.12 0.12 -1.60E-16 Down 0.080089511 Gm19589 "predicted gene, 19589" - - - - "gi|148708161|gb|EDL40108.1|/7.24433e-71/mCG145606, partial [Mus musculus]" 23845 3745 0.156666667 0.153333333 -0.031026896 Down 0.080089511 Clec5a "C-type lectin domain family 5, member a" K10073|1|2e-91|340|mmu:23845|C-type lectin domain family 5 member A GO:0016021//integral component of membrane;GO:0044464;GO:0016021//integral component of membrane;GO:0044464 GO:0005488//binding;GO:0004872//receptor activity;GO:0005488//binding;GO:0004872//receptor activity GO:0006952//defense response;GO:0051707//response to other organism;GO:0006915//apoptotic process;GO:0050663//cytokine secretion;GO:0001649//osteoblast differentiation;GO:0007154//cell communication;GO:0006952//defense response;GO:0051707//response to other organism;GO:0006915//apoptotic process;GO:0050663//cytokine secretion;GO:0001649//osteoblast differentiation;GO:0007154//cell communication gi|84370376|ref|NP_001033693.1|/5.45019e-110/C-type lectin domain family 5 member A isoform 1 [Mus musculus] 140486 8382 0.01 0.013333333 0.415037499 Up 0.080089511 Igf2bp1 insulin-like growth factor 2 mRNA binding protein 1 K17391|1|0.0|1104|mmu:140486|insulin-like growth factor 2 mRNA-binding protein 1 GO:0043234//protein complex;GO:0030425//dendrite;GO:0031981//nuclear lumen;GO:0035770//ribonucleoprotein granule;GO:0031252//cell leading edge;GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0003729//mRNA binding;GO:0036094//small molecule binding GO:0006412//translation;GO:0033554//cellular response to stress;GO:0048255//mRNA stabilization;GO:0033036;GO:0001817//regulation of cytokine production gi|6753518|ref|NP_034081.1|/0/insulin-like growth factor 2 mRNA-binding protein 1 [Mus musculus] 623312 1622 0.923333333 0.926666667 0.005198907 Up 0.080089511 Gm6416 predicted gene 6416 - - - - - 100216455 3018 0.023333333 0.02 -0.222392421 Down 0.080089511 Gm14124 predicted gene 14124 K09228|1|0.0|1022|cge:100770581|KRAB domain-containing zinc finger protein - - - gi|215490123|ref|NP_001135882.1|/0/zinc finger protein family member [Mus musculus] 50917 2545.16 3.606666667 3.603333333 -0.001333976 Down 0.080089511 Galns galactosamine (N-acetyl)-6-sulfate sulfatase K01132|1|0.0|1016|mmu:50917|N-acetylgalactosamine-6-sulfatase [EC:3.1.6.4] GO:0000323//lytic vacuole;GO:0000323//lytic vacuole GO:0008484//sulfuric ester hydrolase activity;GO:0043169//cation binding;GO:0008484//sulfuric ester hydrolase activity;GO:0043169//cation binding - "gi|148679746|gb|EDL11693.1|/0/galactosamine (N-acetyl)-6-sulfate sulfatase, isoform CRA_a, partial [Mus musculus]" 319487 2793 0.023333333 0.02 -0.222392421 Down 0.080089511 A230028O05Rik RIKEN cDNA A230028O05 gene - - - - "gi|148665264|gb|EDK97680.1|/2.42786e-56/mCG144830, partial [Mus musculus]" 75280 1603 0.036666667 0.033333333 -0.137503524 Down 0.080089511 4930554G24Rik RIKEN cDNA 4930554G24 gene - - - - - 327956 672 0.08 0.08 0 - 0.080089511 Vmo1 vitelline membrane outer layer 1 homolog (chicken) K02738|1|4e-12|73.6|fch:102054319|20S proteasome subunit beta 1 [EC:3.4.25.1] - - GO:0035803//egg coat formation gi|61888888|ref|NP_001013625.1|/3.52805e-108/vitelline membrane outer layer protein 1 homolog precursor [Mus musculus] 217733 3369 0.02 0.02 0 - 0.080089511 Tmem63c transmembrane protein 63c K10165|1|6e-22|109|cjc:100414962|nucleotide-binding oligomerization domain-containing protein 2 GO:0031224//intrinsic component of membrane - - gi|27369826|ref|NP_766171.1|/0/calcium permeable stress-gated cation channel 1 [Mus musculus] 12374 7645 0.013333333 0.016666667 0.321928095 Up 0.080089511 Casr calcium-sensing receptor K04612|1|0.0|1922|mmu:12374|calcium-sensing receptor - - - - 108837 5679 4.253333333 4.256666667 0.001130196 Up 0.080089511 Ibtk inhibitor of Bruton agammaglobulinemia tyrosine kinase K10523|1|1e-14|86.3|bmor:101745828|speckle-type POZ protein;K10481|4|2e-13|82.0|dwi:Dwil_GK22423|BTB/POZ domain-containing protein 9;K10457|5|9e-13|79.7|crg:105341714|kelch-like protein 20 GO:0031981//nuclear lumen GO:0004860//protein kinase inhibitor activity;GO:0019900//kinase binding GO:0006469//negative regulation of protein kinase activity;GO:0051283//negative regulation of sequestering of calcium ion gi|124486857|ref|NP_001074751.1|/0/inhibitor of Bruton tyrosine kinase [Mus musculus] 15572 3763 0.02 0.02 0 - 0.080089511 Elavl4 "ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)" K13208|1|0.0|700|mdo:100021505|ELAV like protein 2/3/4 - GO:0036094//small molecule binding;GO:0003723//RNA binding;GO:0036094//small molecule binding;GO:0003723//RNA binding - "gi|611985946|ref|XP_007480256.1|/0/PREDICTED: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 isoform X1 [Monodelphis domestica]" 54422 3391 0.02 0.02 0 - 0.080089511 Barhl1 BarH-like 1 (Drosophila) K09360|1|1e-155|553|rno:117232|BarH-like GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle "GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0003677//DNA binding;GO:0000982//transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0003677//DNA binding" GO:0016477//cell migration;GO:0050954//sensory perception of mechanical stimulus;GO:0007420//brain development;GO:0043066//negative regulation of apoptotic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0016477//cell migration;GO:0050954//sensory perception of mechanical stimulus;GO:0007420//brain development;GO:0043066//negative regulation of apoptotic process;GO:0006366//transcription from RNA polymerase II promoter "gi|148676454|gb|EDL08401.1|/3.98727e-157/BarH-like 1 (Drosophila), isoform CRA_b, partial [Mus musculus]" 228432 6026 0.016666667 0.013333333 -0.321928095 Down 0.080089511 Ano3 anoctamin 3 K19498|1|0.0|1920|mmu:228432|anoctamin-3 GO:0034702//ion channel complex GO:0005254//chloride channel activity GO:0015698//inorganic anion transport gi|189409057|ref|NP_001121575.1|/0/anoctamin-3 [Mus musculus] 432870 2156 0.696666667 0.693333333 -0.006919414 Down 0.080089511 Gm5464 predicted gene 5464 - - - - gi|85702228|ref|NP_001030053.1|/5.502e-82/uncharacterized protein LOC432870 [Mus musculus] 13176 10325 0.01 0.01 0 - 0.080089511 Dcc deleted in colorectal carcinoma K06765|1|0.0|2788|mmu:13176|deleted in colorectal carcinoma GO:0030426//growth cone;GO:0031224//intrinsic component of membrane;GO:0044444//cytoplasmic part GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0004888//transmembrane signaling receptor activity GO:0007411//axon guidance;GO:0014075//response to amine;GO:0007166//cell surface receptor signaling pathway;GO:0006915//apoptotic process;GO:0030308//negative regulation of cell growth;GO:0012502//induction of programmed cell death;GO:0010977//negative regulation of neuron projection development;GO:0021952//central nervous system projection neuron axonogenesis;GO:0043410//positive regulation of MAPK cascade;GO:0016477//cell migration gi|117168295|ref|NP_031857.2|/0/netrin receptor DCC precursor [Mus musculus] 68279 2496 0.063333333 0.06 -0.078002512 Down 0.080089511 Mcoln2 mucolipin 2 K04993|1|0.0|1087|mmu:68279|mucolipin 2 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0044765//single-organism transport;GO:0044765//single-organism transport gi|21389327|ref|NP_080932.2|/0/mucolipin-2 isoform 1 [Mus musculus] 319642 3761 0.086666667 0.086666667 0 - 0.080089511 Rab9b "RAB9B, member RAS oncogene family" K07900|1|8e-114|414|mmu:319642|Ras-related protein Rab-9B GO:0030666//endocytic vesicle membrane GO:0032550 GO:0035556//intracellular signal transduction;GO:0006892//post-Golgi vesicle-mediated transport;GO:0045184//establishment of protein localization gi|28892801|ref|NP_795945.1|/6.76164e-113/ras-related protein Rab-9B [Mus musculus] 17116 2793 0.036666667 0.036666667 0 - 0.080089511 Mab21l1 mab-21-like 1 (C. elegans) K17834|1|4e-17|93.2|cge:100758179|cyclic GMP-AMP synthase [EC:2.7.7.86] GO:0043231//intracellular membrane-bounded organelle - GO:0009790//embryo development;GO:0008283//cell proliferation;GO:0001654//eye development gi|727020071|ref|XP_010398626.1|/0/PREDICTED: protein mab-21-like 1 [Corvus cornix cornix] 17968 4893 0.013333333 0.016666667 0.321928095 Up 0.080089511 Ncam2 neural cell adhesion molecule 2 K06491|1|0.0|1345|mmu:17968|neural cell adhesion molecule GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0031224//intrinsic component of membrane - GO:0022610;GO:0022610;GO:0007606//sensory perception of chemical stimulus gi|6754920|ref|NP_035084.1|/0/neural cell adhesion molecule 2 isoform b precursor [Mus musculus] 243548 7861.49 0.986666667 0.983333333 -0.004882221 Down 0.080089511 Prickle2 prickle planar cell polarity protein 2 K04511|1|0.0|1588|mmu:243548|prickle GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding GO:0030030//cell projection organization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0030030//cell projection organization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0030030//cell projection organization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0030030//cell projection organization;GO:0035088//establishment or maintenance of apical/basal cell polarity gi|755516743|ref|XP_011239654.1|/0/PREDICTED: prickle-like protein 2 isoform X2 [Mus musculus] 245596 4114 0.02 0.016666667 -0.263034406 Down 0.080089511 Hdx highly divergent homeobox - GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0001071//nucleic acid binding transcription factor activity "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|148682069|gb|EDL14016.1|/0/mCG1030964 [Mus musculus] 408022 3813 0.463333333 0.466666667 0.010341944 Up 0.080089511 Primpol primase and polymerase (DNA-directed) K11513|1|3e-12|77.4|mmu:71876|centromere protein U - - GO:0006259//DNA metabolic process gi|47564100|ref|NP_001001184.1|/0/DNA-directed primase/polymerase protein [Mus musculus] 69739 970 0.056666667 0.056666667 0 - 0.080089511 2410004I01Rik RIKEN cDNA 2410004I01 gene - - - - - 19223 1751 7.433333333 7.433333333 0 - 0.080089511 Ptgis prostaglandin I2 (prostacyclin) synthase K01831|1|0.0|959|mmu:19223|prostacyclin synthase [EC:5.3.99.4] GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0031090//organelle membrane;GO:0044421;GO:0044459 GO:0046914//transition metal ion binding;GO:0016491//oxidoreductase activity;GO:0046906//tetrapyrrole binding;GO:0016860//intramolecular oxidoreductase activity GO:0001525//angiogenesis;GO:0006693//prostaglandin metabolic process;GO:0006915//apoptotic process;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0006809//nitric oxide biosynthetic process;GO:0009967//positive regulation of signal transduction;GO:0001666//response to hypoxia;GO:0006954//inflammatory response;GO:0070741//response to interleukin-6;GO:0070555//response to interleukin-1 gi|6679535|ref|NP_032994.1|/0/prostacyclin synthase precursor [Mus musculus] 219134 3164 0.19 0.19 0 - 0.080089511 Shisa2 shisa family member 2 - GO:0031224//intrinsic component of membrane - GO:0032502//developmental process gi|21703918|ref|NP_663438.1|/6.73241e-143/protein shisa-2 homolog precursor [Mus musculus] 69926 14889 0.143333333 0.14 -0.033947332 Down 0.080089511 Dnah17 "dynein, axonemal, heavy chain 17" "K10408|1|0.0|8597|mmu:69926|dynein heavy chain, axonemal" - - - "gi|283837762|ref|NP_001161218.1|/0/dynein heavy chain 17, axonemal [Mus musculus]" 385658 6430 0.256666667 0.253333333 -0.018859027 Down 0.080089511 Nxpe3 "neurexophilin and PC-esterase domain family, member 3" "K15010|1|7e-44|183|xma:102227992|homer;K02324|2|6e-27|127|sko:100367259|DNA polymerase epsilon subunit 1 [EC:2.7.7.7];K07422|3|5e-21|107|bfo:BRAFLDRAFT_72966|cytochrome P450, family 2, subfamily U, polypeptide 1;K14306|4|4e-06|57.8|hro:HELRODRAFT_84833|nuclear pore complex protein Nup62" - - - gi|197333803|ref|NP_001127929.1|/0/NXPE family member 3 [Mus musculus] 380785 2728 0.326666667 0.323333333 -0.014797002 Down 0.080089511 Begain brain-enriched guanylate kinase-associated K06105|1|6e-47|192|ola:101170119|tight junction protein 4 (peripheral) GO:0044297//cell body;GO:0043005//neuron projection;GO:0044424 GO:0042802//identical protein binding - gi|253683505|ref|NP_001156647.1|/0/brain-enriched guanylate kinase-associated protein [Mus musculus] 240322 4666 0.106666667 0.103333333 -0.04580369 Down 0.080089511 Adamts19 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19" K08633|1|0.0|2227|mmu:240322|a disintegrin and metalloproteinase with thrombospondin motifs 19 [EC:3.4.24.-] GO:0031012//extracellular matrix "GO:0046914//transition metal ion binding;GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019538//protein metabolic process;GO:0007166//cell surface receptor signaling pathway gi|28202057|ref|NP_780715.1|/0/A disintegrin and metalloproteinase with thrombospondin motifs 19 precursor [Mus musculus] 380768 4399 0.023333333 0.023333333 0 - 0.080089511 Ccdc177 coiled-coil domain containing 177 - - - - - 11471 1424 0.043333333 0.04 -0.115477217 Down 0.080089511 Actl7b actin-like 7b K05692|1|4e-87|324|cmk:103183476|actin beta/gamma 1 GO:0043232 - - gi|146198843|ref|NP_079547.2|/0/actin-like protein 7B [Mus musculus] 100043688 3723 0.04 0.036666667 -0.125530882 Down 0.080089511 Amy2a2 amylase 2a2 K01176|1|0.0|1090|mmu:100043688|alpha-amylase [EC:3.2.1.1] GO:0044421 GO:0046872//metal ion binding;GO:0043168//anion binding;GO:0016160//amylase activity GO:0005975//carbohydrate metabolic process "gi|148680466|gb|EDL12413.1|/0/mCG11265, isoform CRA_a, partial [Mus musculus]" 320635 2724 2.57 2.57 0 - 0.080089511 Cyb5r2 cytochrome b5 reductase 2 K00326|1|3e-156|555|mmu:320635|cytochrome-b5 reductase [EC:1.6.2.2] GO:0043231//intracellular membrane-bounded organelle "GO:0016653//oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor" GO:0006694//steroid biosynthetic process gi|568950867|ref|XP_006508010.1|/0/PREDICTED: NADH-cytochrome b5 reductase 2 isoform X2 [Mus musculus] 239556 9833 0.013333333 0.01 -0.415037499 Down 0.080089511 Cacna1i "calcium channel, voltage-dependent, alpha 1I subunit" K04856|1|0.0|3385|mmu:239556|voltage-dependent calcium channel T type alpha-1I - - - gi|157057194|ref|NP_001037773.2|/0/voltage-dependent T-type calcium channel subunit alpha-1I [Mus musculus] 381371 643 0.09 0.086666667 -0.054447784 Down 0.080089511 Platr26 pluripotency associated transcript 26 - - - - gi|40556863|gb|AAR87789.1|/5.57607e-65/unknown [Mus musculus] 57385 4434 0.036666667 0.036666667 0 - 0.080089511 P2ry4 "pyrimidinergic receptor P2Y, G-protein coupled, 4" "K04271|1|0.0|720|mmu:57385|purinergic receptor P2Y, G protein-coupled, 4" GO:0031224//intrinsic component of membrane;GO:0044459 GO:0032550;GO:0015065//uridine nucleotide receptor activity;GO:0000166//nucleotide binding GO:0006821//chloride transport;GO:0035588 gi|10181172|ref|NP_065646.1|/0/P2Y purinoceptor 4 [Mus musculus] 12569 4166 0.173333333 0.17 -0.028014376 Down 0.080089511 Cdk5r1 "cyclin-dependent kinase 5, regulatory subunit 1 (p35)" K11716|1|5e-148|528|rno:116671|cyclin-dependent kinase 5 activator 1 GO:0043232;GO:0044327//dendritic spine head;GO:0045202//synapse;GO:0044444//cytoplasmic part;GO:0019908//nuclear cyclin-dependent protein kinase holoenzyme complex;GO:0044297//cell body;GO:0016020//membrane GO:0004674//protein serine/threonine kinase activity;GO:0005102//receptor binding;GO:0046872//metal ion binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0019900//kinase binding;GO:0050839//cell adhesion molecule binding "GO:0048814//regulation of dendrite morphogenesis;GO:0043065//positive regulation of apoptotic process;GO:0007215//glutamate receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0006351//transcription, DNA-templated;GO:0090313;GO:0007409//axonogenesis;GO:0006935//chemotaxis;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0000226//microtubule cytoskeleton organization;GO:0042501//serine phosphorylation of STAT protein;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030308//negative regulation of cell growth;GO:0045860//positive regulation of protein kinase activity;GO:0021586//pons maturation;GO:0021795//cerebral cortex cell migration" gi|6753384|ref|NP_034001.1|/4.6947e-147/cyclin-dependent kinase 5 activator 1 [Mus musculus] 547431 2563 0.043333333 0.04 -0.115477217 Down 0.080089511 Btnl2 butyrophilin-like 2 K06712|1|6e-51|205|oaa:100090424|butyrophilin GO:0031224//intrinsic component of membrane - - gi|83721945|ref|NP_524574.1|/0/butyrophilin-like protein 2 [Mus musculus] 243659 3378 0.01 0.01 0 - 0.080089511 Styk1 serine/threonine/tyrosine kinase 1 K17510|1|0.0|788|mmu:243659|tyrosine-protein kinase STYK1 [EC:2.7.10.2] GO:0016020//membrane GO:0032550 - gi|27370362|ref|NP_766479.1|/0/tyrosine-protein kinase STYK1 [Mus musculus] 72522 2518.09 2.423333333 2.42 -0.001985816 Down 0.080089511 Atxn7l2 ataxin 7-like 2 K11318|1|0.0|1291|mmu:72522|ataxin-7 - - - gi|575501658|ref|NP_001276474.1|/0/ataxin-7-like protein 2 isoform 1 [Mus musculus] 233987 2361 1.34 1.343333333 0.003584337 Up 0.080089511 Zfp958 zinc finger protein 958 K09228|1|0.0|1034|mmu:233987|KRAB domain-containing zinc finger protein - GO:0046872//metal ion binding - gi|21704192|ref|NP_663566.1|/0/zinc finger protein 878 [Mus musculus] 23920 5102 0.01 0.013333333 0.415037499 Up 0.080089511 Insrr insulin receptor-related receptor K05086|1|0.0|2629|mmu:23920|insulin receptor-related receptor [EC:2.7.10.1] GO:0031224//intrinsic component of membrane GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding GO:0006468//protein phosphorylation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0010446//response to alkaline pH;GO:0030036//actin cytoskeleton organization;GO:0007275//multicellular organism development gi|160333073|ref|NP_035962.2|/0/insulin receptor-related protein precursor [Mus musculus] 244864 1786 2.543333333 2.54 -0.001892059 Down 0.080089511 Layn layilin K10077|1|0.0|744|mmu:244864|layilin GO:0031224//intrinsic component of membrane;GO:0005924//cell-substrate adherens junction;GO:0031252//cell leading edge GO:0005539//glycosaminoglycan binding - gi|226958426|ref|NP_001028706.1|/0/layilin precursor [Mus musculus] 20666 8451 0.01 0.013333333 0.415037499 Up 0.080089511 Sox11 SRY (sex determining region Y)-box 11 K09268|1|4e-139|499|mmu:20666|transcription factor SOX4/11/12 (SOX group C) - - - - 244144 3982 0.433333333 0.43 -0.011140558 Down 0.080089511 Usp35 ubiquitin specific peptidase 35 K11854|1|0.0|1812|mmu:244144|ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12] - "GO:0070011//peptidase activity, acting on L-amino acid peptides" GO:0019941//modification-dependent protein catabolic process gi|294459917|ref|NP_001170883.1|/0/ubiquitin carboxyl-terminal hydrolase 35 [Mus musculus] 15563 5576 0.01 0.013333333 0.415037499 Up 0.080089511 Htr5a 5-hydroxytryptamine (serotonin) receptor 5A K04161|1|0.0|662|mmu:15563|5-hydroxytryptamine receptor 5 GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body;GO:0005783//endoplasmic reticulum GO:0008227//G-protein coupled amine receptor activity GO:0021543//pallium development;GO:0043627//response to estrogen;GO:0046058//cAMP metabolic process;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0007186//G-protein coupled receptor signaling pathway gi|84370345|ref|NP_032340.2|/0/5-hydroxytryptamine receptor 5A [Mus musculus] 20910 3891.76 7.68 7.68 -1.60E-16 Down 0.080089511 Stxbp1 syntaxin binding protein 1 K15292|1|0.0|1063|hgl:101726395|syntaxin-binding protein 1 GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0030141//secretory granule;GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0030141//secretory granule GO:0019900//kinase binding;GO:0019905//syntaxin binding;GO:0019900//kinase binding;GO:0019905//syntaxin binding "GO:0016082//synaptic vesicle priming;GO:0015980//energy derivation by oxidation of organic compounds;GO:0030168//platelet activation;GO:0043066//negative regulation of apoptotic process;GO:0031647//regulation of protein stability;GO:0006835//dicarboxylic acid transport;GO:0017156//calcium ion regulated exocytosis;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0048167//regulation of synaptic plasticity;GO:0016050//vesicle organization;GO:0030073//insulin secretion;GO:0045184//establishment of protein localization;GO:0016082//synaptic vesicle priming;GO:0015980//energy derivation by oxidation of organic compounds;GO:0030168//platelet activation;GO:0043066//negative regulation of apoptotic process;GO:0031647//regulation of protein stability;GO:0006835//dicarboxylic acid transport;GO:0017156//calcium ion regulated exocytosis;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0048167//regulation of synaptic plasticity;GO:0016050//vesicle organization;GO:0030073//insulin secretion;GO:0045184//establishment of protein localization" "gi|148676634|gb|EDL08581.1|/0/syntaxin binding protein 1, isoform CRA_b, partial [Mus musculus]" 109198 1801 0.033333333 0.03 -0.152003093 Down 0.080089511 6030407O03Rik RIKEN cDNA 6030407O03 gene - - - - - 627214 4637 0.353333333 0.353333333 0 - 0.080089511 Fam196a "family with sequence similarity 196, member A" - - - - gi|219689092|ref|NP_001137274.1|/0/protein FAM196A [Mus musculus] 77875 1114 0.05 0.05 0 - 0.080089511 Cyp4f41-ps "cytochrome P450, family 4, subfamily f, polypeptide 41 pseudogene" - - - - - 14633 6708 0.376666667 0.376666667 0 - 0.080089511 Gli2 GLI-Kruppel family member GLI2 K16798|1|0.0|2855|mmu:14633|zinc finger protein GLI2 - - - - 331493 1809 0.033333333 0.03 -0.152003093 Down 0.080089511 Gm5127 predicted gene 5127 K04275|1|8e-09|64.7|mze:101469114|lysophosphatidic acid receptor 4;K10042|2|4e-06|55.8|lcm:102351849|succinate receptor 1 - - - "gi|148682101|gb|EDL14048.1|/1.07657e-120/mCG144646, partial [Mus musculus]" 330369 6513.04 0.013333333 0.01 -0.415037499 Down 0.080089511 Fbxo41 F-box protein 41 K10316|1|0.0|1285|mmu:330369|F-box protein 41 - - - - 78808 9074 1.553333333 1.556666667 0.003092595 Up 0.080089511 Stxbp5 syntaxin binding protein 5 (tomosyn) K08518|1|0.0|2120|mmu:78808|syntaxin-binding protein 5 - - - - 100043247 914 0.013333333 0.01 -0.415037499 Down 0.080089511 Gm4312 predicted gene 4312 K12881|1|1e-103|378|mmu:100043292|THO complex subunit 4 GO:0043234//protein complex;GO:0005681//spliceosomal complex GO:0043566//structure-specific DNA binding GO:0006406//mRNA export from nucleus gi|262263336|ref|NP_001160109.1|/3.5709e-114/uncharacterized protein LOC100043224 [Mus musculus] 12290 12697 0.01 0.01 0 - 0.080089511 Cacna1e "calcium channel, voltage-dependent, R type, alpha 1E subunit" K04852|1|0.0|3789|mmu:12290|voltage-dependent calcium channel R type alpha-1E - - - gi|568908063|ref|XP_006529162.1|/0/PREDICTED: voltage-dependent R-type calcium channel subunit alpha-1E isoform X10 [Mus musculus] 94090 4458 0.016666667 0.016666667 0 - 0.080089511 Trim9 tripartite motif-containing 9 K10649|1|0.0|1505|mmu:94090|tripartite motif-containing protein 9/67 - - - - 16517 3650.66 0.236666667 0.233333333 -0.020464103 Down 0.080089511 Kcnj16 "potassium inwardly-rectifying channel, subfamily J, member 16" K05009|1|0.0|827|mmu:16517|potassium inwardly-rectifying channel subfamily J member 16 GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity;GO:0005488//binding;GO:0005249//voltage-gated potassium channel activity GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|130505929|ref|NP_034734.3|/0/inward rectifier potassium channel 16 [Mus musculus] 66641 2798 7.576666667 7.576666667 -1.60E-16 Down 0.080089511 Sike1 suppressor of IKBKE 1 K12656|1|2e-96|356|mmu:66641|suppressor of IKK-epsilon GO:0044424;GO:0005924//cell-substrate adherens junction;GO:0043227//membrane-bounded organelle - - gi|13385140|ref|NP_079955.1|/2.03683e-95/suppressor of IKBKE 1 [Mus musculus] 71046 1124 0.093333333 0.093333333 0 - 0.080089511 4933405L10Rik RIKEN cDNA 4933405L10 gene - - - - gi|198278507|ref|NP_081931.1|/7.50422e-118/uncharacterized protein C16orf86 homolog [Mus musculus] 244713 4050 3.516666667 3.513333333 -0.001368132 Down 0.080089511 Zfp317 zinc finger protein 317 K09228|1|0.0|1296|mmu:244713|KRAB domain-containing zinc finger protein GO:0044464 GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|257153396|ref|NP_766506.4|/0/zinc finger protein 317 [Mus musculus] 331374 7172 0.013333333 0.013333333 0 - 0.080089511 Dgkk diacylglycerol kinase kappa K00901|1|0.0|2125|mmu:331374|diacylglycerol kinase (ATP) [EC:2.7.1.107] - - - gi|189491687|ref|NP_808582.3|/0/diacylglycerol kinase kappa [Mus musculus] 18507 1208 0.05 0.046666667 -0.099535674 Down 0.080089511 Pax5 paired box 5 K09383|1|0.0|676|mmu:18507|paired box protein 5 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0001071//nucleic acid binding transcription factor activity;GO:0003676//nucleic acid binding GO:0009653//anatomical structure morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0007519//skeletal muscle tissue development;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0031061//negative regulation of histone methylation gi|6679213|ref|NP_032808.1|/0/paired box protein Pax-5 [Mus musculus] 407812 3909 0.053333333 0.056666667 0.087462841 Up 0.080089511 Zfp941 zinc finger protein 941 K09228|1|1e-161|573|hgl:101723100|KRAB domain-containing zinc finger protein - GO:0043169//cation binding - gi|142383655|ref|NP_001001180.2|/0/uncharacterized protein LOC407812 [Mus musculus] 71265 1266 0.046666667 0.043333333 -0.106915204 Down 0.080089511 4933431G14Rik RIKEN cDNA 4933431G14 gene - - - - - 328354 1921 0.106666667 0.103333333 -0.04580369 Down 0.080089511 Gm5087 predicted gene 5087 - - - - - 223917 2113 0.03 0.03 0 - 0.080089511 Krt79 keratin 79 "K07605|1|0.0|794|mmu:223917|type II keratin, basic" GO:0005882//intermediate filament - - "gi|148672069|gb|EDL04016.1|/0/cDNA sequence BC031593, partial [Mus musculus]" 23956 1588 0.04 0.036666667 -0.125530882 Down 0.080089511 Neu2 neuraminidase 2 K12357|1|0.0|790|mmu:23956|sialidase-2/3/4 [EC:3.2.1.18] GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part;GO:0044444//cytoplasmic part GO:0004308//exo-alpha-sialidase activity;GO:0004308//exo-alpha-sialidase activity;GO:0004308//exo-alpha-sialidase activity;GO:0004308//exo-alpha-sialidase activity GO:0010830//regulation of myotube differentiation;GO:0097305//response to alcohol;GO:0045445//myoblast differentiation;GO:0010830//regulation of myotube differentiation;GO:0097305//response to alcohol;GO:0045445//myoblast differentiation;GO:0010830//regulation of myotube differentiation;GO:0097305//response to alcohol;GO:0045445//myoblast differentiation;GO:0010830//regulation of myotube differentiation;GO:0097305//response to alcohol;GO:0045445//myoblast differentiation gi|237512993|ref|NP_001153637.1|/0/sialidase-2 isoform 3 [Mus musculus] 20450 5376 0.063333333 0.066666667 0.074000581 Up 0.080089511 St8sia2 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2" "K06612|1|0.0|726|mmu:20450|alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8B) [EC:2.4.99.-]" GO:0031228//intrinsic component of Golgi membrane GO:0031406//carboxylic acid binding;GO:0008373//sialyltransferase activity GO:0048731//system development;GO:0006935//chemotaxis;GO:0001573//ganglioside metabolic process;GO:0006487//protein N-linked glycosylation "gi|164698489|ref|NP_033207.2|/0/alpha-2,8-sialyltransferase 8B precursor [Mus musculus]" 270893 4415 0.03 0.033333333 0.152003093 Up 0.080089511 Tmem132e transmembrane protein 132E K17599|1|0.0|1741|mmu:270893|transmembrane protein 132 GO:0031224//intrinsic component of membrane - - gi|750321368|ref|NP_001291368.1|/0/transmembrane protein 132E precursor [Mus musculus] 13842 4732 0.016666667 0.016666667 0 - 0.080089511 Epha8 Eph receptor A8 K05109|1|0.0|1922|mmu:13842|Eph receptor A8 [EC:2.7.10.1] GO:0016021//integral component of membrane;GO:0005769//early endosome;GO:0042995//cell projection GO:0032550;GO:0005003//ephrin receptor activity GO:0030155//regulation of cell adhesion;GO:0042551//neuron maturation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0030030//cell projection organization;GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade;GO:0006935//chemotaxis;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0016477//cell migration gi|154240697|ref|NP_031965.2|/0/ephrin type-A receptor 8 precursor [Mus musculus] 12902 6207 0.013333333 0.01 -0.415037499 Down 0.080089511 Cr2 complement receptor 2 K04012|1|0.0|2228|mmu:12902|complement receptor type 2 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity GO:0046649//lymphocyte activation;GO:0006952//defense response;GO:0002455//humoral immune response mediated by circulating immunoglobulin "gi|148680981|gb|EDL12928.1|/0/complement receptor 2, partial [Mus musculus]" 12057 2420 0.043333333 0.04 -0.115477217 Down 0.080089511 Opn1sw "opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)" K04252|1|0.0|686|mmu:12057|short wavelength-sensitive opsin GO:0031224//intrinsic component of membrane;GO:0033267;GO:0031513//nonmotile primary cilium GO:0004888//transmembrane signaling receptor activity GO:0050953//sensory perception of light stimulus;GO:0006464//cellular protein modification process;GO:0007166//cell surface receptor signaling pathway gi|6680776|ref|NP_031564.1|/0/short-wave-sensitive opsin 1 [Mus musculus] 15571 5027 0.13 0.126666667 -0.037474705 Down 0.080089511 Elavl3 "ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)" K13208|1|1e-180|637|rno:282824|ELAV like protein 2/3/4 - GO:0036094//small molecule binding;GO:0003723//RNA binding GO:0048731//system development;GO:0048869//cellular developmental process gi|27229298|ref|NP_758827.1|/1.14744e-179/ELAV-like protein 3 [Rattus norvegicus] 546049 1621 0.386666667 0.383333333 -0.012490944 Down 0.080089511 C330021F23Rik RIKEN cDNA C330021F23 gene K02973|1|2e-73|278|ptg:102972452|small subunit ribosomal protein S23e GO:0015935//small ribosomal subunit GO:0005488//binding;GO:0005198//structural molecule activity GO:0006412//translation;GO:0019080;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006613//cotranslational protein targeting to membrane gi|586975096|ref|XP_003981174.2|/2.11094e-72/PREDICTED: 40S ribosomal protein S23 [Felis catus] 74255 3273 13.58 13.58 0 - 0.080089511 Smu1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) K13111|1|0.0|1028|pale:102879000|WD40 repeat-containing protein SMU1 GO:0043231//intracellular membrane-bounded organelle - - gi|84370185|ref|NP_001033662.1|/0/WD40 repeat-containing protein SMU1 [Bos taurus] 381628 3108 0.023333333 0.02 -0.222392421 Down 0.080089511 Adgrf3 adhesion G protein-coupled receptor F3 K08456|1|0.0|1879|mmu:381628|G protein-coupled receptor 113 - - - gi|117553629|ref|NP_001014416.2|/0/adhesion G-protein coupled receptor F3 precursor [Mus musculus] 100039148 2914 0.05 0.046666667 -0.099535674 Down 0.080089511 Gm12128 predicted gene 12128 - - - - - 75266 596 0.09 0.093333333 0.05246742 Up 0.080089511 Tomm20l translocase of outer mitochondrial membrane 20 homolog (yeast)-like K17770|1|3e-73|276|mmu:75266|mitochondrial import receptor subunit TOM20 GO:0031224//intrinsic component of membrane;GO:0005741//mitochondrial outer membrane - GO:0006886//intracellular protein transport gi|259089421|ref|NP_083503.1|/2.30693e-72/TOMM20-like protein 1 [Mus musculus] 666422 1660 0.013333333 0.01 -0.415037499 Down 0.080089511 Gm8096 3-phosphoglycerate dehydrogenase pseudogene K00058|1|0.0|444|mmu:236539|D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95] GO:0044444//cytoplasmic part "GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding" GO:0007417//central nervous system development;GO:0007049//cell cycle;GO:0030030//cell projection organization;GO:0006790//sulfur compound metabolic process;GO:0009064//glutamine family amino acid metabolic process;GO:0010001//glial cell differentiation;GO:0008652//cellular amino acid biosynthetic process;GO:0006563//L-serine metabolic process;GO:0010467//gene expression;GO:0009066 gi|52353955|ref|NP_058662.2|/0/D-3-phosphoglycerate dehydrogenase [Mus musculus] 101434 1391 0.073333333 0.076666667 0.064130337 Up 0.080089511 Ceacam15 carcinoembryonic antigen-related cell adhesion molecule 15 K06499|1|8e-54|213|cge:103159444|carcinoembryonic antigen-related cell adhesion molecule - - - gi|189409173|ref|NP_780524.1|/1.3742e-130/CEA-related cell adhesion molecule 15 [Mus musculus] 319504 7362 0.086666667 0.09 0.054447784 Up 0.080089511 Nrcam neuronal cell adhesion molecule K06756|1|0.0|2312|cge:100763077|neuronal cell adhesion molecule GO:0031224//intrinsic component of membrane;GO:0033267 GO:0008092//cytoskeletal protein binding GO:0007411//axon guidance;GO:0045161//neuronal ion channel clustering;GO:0007155//cell adhesion;GO:0033036;GO:0050877//neurological system process gi|28972161|dbj|BAC65534.1|/0/mKIAA0343 protein [Mus musculus] 234865 5808 3.953333333 3.956666667 0.001215925 Up 0.080089511 Nup133 nucleoporin 133 K14300|1|0.0|2189|mmu:234865|nuclear pore complex protein Nup133 - - - gi|283806543|ref|NP_758492.2|/0/nuclear pore complex protein Nup133 [Mus musculus] 54156 2700 0.063333333 0.063333333 0 - 0.080089511 Egfl6 "EGF-like-domain, multiple 6" K06824|1|7e-114|414|lcm:102363603|nephronectin GO:0005578//proteinaceous extracellular matrix - GO:0043062//extracellular structure organization;GO:0010810//regulation of cell-substrate adhesion;GO:0048869//cellular developmental process gi|9506563|ref|NP_062270.1|/0/epidermal growth factor-like protein 6 precursor [Mus musculus] 15109 2776 0.023333333 0.023333333 0 - 0.080089511 Hal histidine ammonia lyase K01745|1|0.0|1275|mmu:15109|histidine ammonia-lyase [EC:4.3.1.3] - - - - 64337 438 0.243333333 0.24 -0.019899557 Down 0.080089511 Gng13 "guanine nucleotide binding protein (G protein), gamma 13" K04547|1|9e-40|163|cge:100774382|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 GO:0031234//extrinsic component of cytoplasmic side of plasma membrane GO:0060089 GO:0007606//sensory perception of chemical stimulus;GO:0007186//G-protein coupled receptor signaling pathway gi|344248288|gb|EGW04392.1|/8.80317e-39/Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [Cricetulus griseus] 381142 2247 0.03 0.026666667 -0.169925001 Down 0.080089511 Arl14epl ADP-ribosylation factor-like 14 effector protein-like - - - - gi|85701959|ref|NP_001028618.1|/1.02012e-86/ARL14 effector protein-like [Mus musculus] 328234 3456 0.02 0.02 0 - 0.080089511 Rnf182 ring finger protein 182 K11983|1|1e-110|404|mmu:328234|E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27] GO:0043227//membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0044424 GO:0046914//transition metal ion binding;GO:0019787//ubiquitin-like protein transferase activity GO:0032446//protein modification by small protein conjugation gi|34147266|ref|NP_899027.1|/1.08385e-109/E3 ubiquitin-protein ligase RNF182 [Mus musculus] 233332 6043 0.256666667 0.26 0.018615678 Up 0.080089511 Adamts17 "a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17" K08631|1|0.0|2315|mmu:233332|a disintegrin and metalloproteinase with thrombospondin motifs 17 [EC:3.4.24.-] - - - - 74992 895 0.063333333 0.06 -0.078002512 Down 0.080089511 4930487H11Rik RIKEN cDNA 4930487H11 gene - - - - - 100502841 9672 1.316666667 1.313333333 -0.003657024 Down 0.080089511 Epg5 ectopic P-granules autophagy protein 5 homolog (C. elegans) - - - GO:0044248 gi|307344699|ref|NP_001182562.1|/0/ectopic P granules protein 5 homolog [Mus musculus] 327954 13704 0.076666667 0.073333333 -0.064130337 Down 0.080089511 Dnah2 "dynein, axonemal, heavy chain 2" "K10408|1|0.0|8777|mmu:327954|dynein heavy chain, axonemal" GO:0030286//dynein complex;GO:0043231//intracellular membrane-bounded organelle GO:0003774//motor activity;GO:0032550 GO:0048870//cell motility "gi|124486773|ref|NP_001074799.1|/0/dynein heavy chain 2, axonemal [Mus musculus]" 102075 4167 0.05 0.046666667 -0.099535674 Down 0.080089511 Plekhg4 "pleckstrin homology domain containing, family G (with RhoGef domain) member 4" K18655|1|2e-56|224|tsp:Tsp_05574|ATP-dependent RNA helicase DDX19/DBP5 [EC:3.6.4.13];K08810|2|9e-42|175|xtr:100170157|triple functional domain protein [EC:2.7.11.1];K15048|5|4e-40|170|gja:107125643|kalirin [EC:2.7.11.1] - - - gi|124487489|ref|NP_001074802.1|/0/puratrophin-1 [Mus musculus] 74213 4105 1.42 1.416666667 -0.003390589 Down 0.080089511 Rbm26 RNA binding motif protein 26 K13192|1|0.0|1346|mmu:74213|RNA-binding protein 26 - - - "gi|148668185|gb|EDL00515.1|/0/RNA binding motif protein 26, isoform CRA_a, partial [Mus musculus]" 140474 11277 0.016666667 0.013333333 -0.321928095 Down 0.080089511 Muc4 mucin 4 K06825|1|3e-77|295|bfo:BRAFLDRAFT_129967|fibrillin 1;K17307|3|1e-63|249|tad:TRIADDRAFT_53733|fibulin 1/2;K10955|4|6e-30|76.3|mze:101471083|intestinal mucin-2 GO:0044459;GO:0005576//extracellular region;GO:0044424 GO:0005515//protein binding GO:0048519;GO:0048583;GO:0007155//cell adhesion;GO:0050794//regulation of cellular process gi|167736365|ref|NP_536705.3|/0/mucin-4 precursor [Mus musculus] 233079 1906 0.033333333 0.033333333 0 - 0.080089511 Ffar2 free fatty acid receptor 2 K04328|1|3e-178|627|mmu:233079|free fatty acid receptor 2 GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity;GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity;GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity;GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity;GO:0005488//binding;GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway gi|22122727|ref|NP_666299.1|/2.27381e-177/free fatty acid receptor 2 [Mus musculus] 67304 1154 1 1.003333333 0.004800986 Up 0.080089511 3110070M22Rik RIKEN cDNA 3110070M22 gene - - - - "gi|148686395|gb|EDL18342.1|/2.54228e-60/mCG114444, partial [Mus musculus]" 102954 1772 0.13 0.126666667 -0.037474705 Down 0.080089511 Nudt10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 K07766|1|3e-67|258|ngi:103730283|diphosphoinositol-polyphosphate diphosphatase [EC:3.6.1.52] GO:0044424 GO:0052842//inositol diphosphate pentakisphosphate diphosphatase activity;GO:0052841//inositol bisdiphosphate tetrakisphosphate diphosphatase activity;GO:0043169//cation binding - gi|61555249|gb|AAX46684.1|/6.43288e-78/nudix (nucleoside diphosphate linked moiety X)-type motif 11 [Bos taurus] 71247 1163 0.05 0.05 0 - 0.080089511 4933438B17Rik RIKEN cDNA 4933438B17 gene - - - - - 320069 2414 0.026666667 0.023333333 -0.192645078 Down 0.080089511 3830432H09Rik RIKEN cDNA 3830432H09 gene - - - - - 229694 5547 0.023333333 0.02 -0.222392421 Down 0.080089511 AI504432 expressed sequence AI504432 - - - - gi|26333071|dbj|BAC30253.1|/8.58346e-59/unnamed protein product [Mus musculus] 64931 1239 0.05 0.046666667 -0.099535674 Down 0.080089511 Izumo1r "IZUMO1 receptor, JUNO" K13649|1|5e-98|360|mmu:64931|folate receptor - GO:0051183//vitamin transporter activity;GO:0051183//vitamin transporter activity GO:0044763;GO:0006835//dicarboxylic acid transport;GO:0044763;GO:0006835//dicarboxylic acid transport gi|12584982|ref|NP_075026.1|/7.27987e-150/sperm-egg fusion protein Juno isoform 1 precursor [Mus musculus] 229949 3103 0.023333333 0.023333333 0 - 0.080089511 Ak5 adenylate kinase 5 K00939|1|0.0|1123|mmu:229949|adenylate kinase [EC:2.7.4.3] GO:0005815//microtubule organizing center;GO:0044444//cytoplasmic part "GO:0032550;GO:0019205//nucleobase-containing compound kinase activity;GO:0019887//protein kinase regulator activity;GO:0016776//phosphotransferase activity, phosphate group as acceptor" GO:0009152//purine ribonucleotide biosynthetic process;GO:0009153;GO:0007154//cell communication;GO:0006221//pyrimidine nucleotide biosynthetic process gi|124486887|ref|NP_001074746.1|/0/adenylate kinase isoenzyme 5 [Mus musculus] 621239 2141 0.186666667 0.186666667 0 - 0.080089511 Nhlrc4 NHL repeat containing 4 "K03860|1|7e-39|164|shr:100929130|phosphatidylinositol glycan, class Q;K11997|4|8e-14|81.6|bfo:BRAFLDRAFT_84218|tripartite motif-containing protein 2/3" - - - gi|148690529|gb|EDL22476.1|/1.89519e-159/mCG48762 [Mus musculus] 67112 489 0.11 0.11 0 - 0.080089511 Fgf22 fibroblast growth factor 22 K04358|1|2e-77|289|mmu:67112|fibroblast growth factor GO:0031981//nuclear lumen GO:0005102//receptor binding - gi|12963627|ref|NP_075793.1|/1.05056e-76/fibroblast growth factor 22 precursor [Mus musculus] 216393 3427 0.02 0.02 0 - 0.080089511 D930020B18Rik RIKEN cDNA D930020B18 gene - - - - gi|167621420|ref|NP_796309.3|/0/uncharacterized protein C12orf56 homolog [Mus musculus] 67640 1262 0.04 0.04 0 - 0.080089511 4930465K10Rik RIKEN cDNA 4930465K10 gene - - - - "gi|38174301|gb|AAH61021.1|/1.39652e-54/4930465K10Rik protein, partial [Mus musculus]" 768252 3732 0.05 0.053333333 0.093109404 Up 0.080089511 Foxl2os "forkhead box L2, opposite strand" - - - - - 100039211 1537 0.04 0.036666667 -0.125530882 Down 0.080089511 Gm10649 predicted gene 10649 - - - - gi|74187986|dbj|BAE37121.1|/3.61309e-26/unnamed protein product [Mus musculus] 244071 3369 0.023333333 0.02 -0.222392421 Down 0.080089511 Agbl1 ATP/GTP binding protein-like 1 K04257|1|5e-24|116|shr:100920260|olfactory receptor;K05840|2|2e-18|97.8|myb:102243447|dopamine receptor D5 GO:0044424 GO:0008235//metalloexopeptidase activity;GO:0046914//transition metal ion binding;GO:0008092//cytoskeletal protein binding GO:0035608//protein deglutamylation;GO:0018410 gi|312839828|ref|NP_001186153.1|/0/cytosolic carboxypeptidase 4 [Mus musculus] 50500 2978 0.286666667 0.29 0.016678741 Up 0.080089511 Ttpa tocopherol (alpha) transfer protein K19625|1|1e-29|134|cmk:103188381|retinaldehyde-binding protein 1 - - - - 27386 5879 0.02 0.016666667 -0.263034406 Down 0.080089511 Npas3 neuronal PAS domain protein 3 K09098|1|0.0|1507|mmu:27386|neuronal PAS domain-containing protein 1/3 GO:0043231//intracellular membrane-bounded organelle GO:0060089;GO:0005515//protein binding "GO:0060746//parental behavior;GO:0051705;GO:0044708//single-organism behavior;GO:0006351//transcription, DNA-templated;GO:0007154//cell communication" gi|154090947|ref|NP_038808.2|/0/neuronal PAS domain-containing protein 3 [Mus musculus] 329942 13555 0.02 0.02 0 - 0.080089511 Csmd2 CUB and Sushi multiple domains 2 K17495|1|0.0|7391|mmu:329942|CUB and sushi domain-containing protein - - - - 71601 2897 0.023333333 0.023333333 0 - 0.080089511 Ceacam20 carcinoembryonic antigen-related cell adhesion molecule 20 K06499|1|0.0|1083|mmu:71601|carcinoembryonic antigen-related cell adhesion molecule - - - - 552913 1662 0.243333333 0.24 -0.019899557 Down 0.080089511 Gm14634 predicted gene 14634 - - - - - 94190 7018 0.846666667 0.85 0.00566875 Up 0.080089511 Ophn1 oligophrenin 1 K20071|1|2e-174|617|ssc:100520606|Rho GTPase-activating protein 26 GO:0005856//cytoskeleton;GO:0030425//dendrite;GO:0033267 "GO:0008092//cytoskeletal protein binding;GO:0030674//protein binding, bridging;GO:0008289//lipid binding;GO:0035254//glutamate receptor binding;GO:0019904//protein domain specific binding" "GO:0035249//synaptic transmission, glutamatergic;GO:0048731//system development;GO:0007010//cytoskeleton organization;GO:0006897//endocytosis;GO:0030031//cell projection assembly" "gi|148682255|gb|EDL14202.1|/4.01024e-47/oligophrenin 1, isoform CRA_b, partial [Mus musculus]" 54712 7059 0.17 0.173333333 0.028014376 Up 0.080089511 Plxnc1 plexin C1 K06572|1|0.0|3000|mmu:54712|plexin C GO:0044464;GO:0031224//intrinsic component of membrane - GO:0007154//cell communication;GO:0032502//developmental process gi|9055376|ref|NP_061267.1|/0/plexin-C1 precursor [Mus musculus] 50928 1374 0.043333333 0.043333333 0 - 0.080089511 Klrg1 "killer cell lectin-like receptor subfamily G, member 1" K10076|1|3e-110|400|mmu:50928|killer cell lectin-like receptor subfamily G member 1 GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0006952//defense response;GO:0007165//signal transduction gi|8850225|ref|NP_058666.1|/2.93996e-109/killer cell lectin-like receptor subfamily G member 1 [Mus musculus] 100503021 1861 0.05 0.05 0 - 0.080089511 Gm19510 "predicted gene, 19510" - - - - - 57738 4007 1.34 1.336666667 -0.003593265 Down 0.080089511 Slc15a2 "solute carrier family 15 (H+/peptide transporter), member 2" "K14637|1|3e-138|493|mmu:57738|solute carrier family 15 (oligopeptide transporter), member 2" GO:0016021//integral component of membrane;GO:0016021//integral component of membrane GO:0019534//toxin transporter activity;GO:0015198//oligopeptide transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0019534//toxin transporter activity;GO:0015198//oligopeptide transporter activity;GO:0015291//secondary active transmembrane transporter activity GO:0015893//drug transport;GO:0006857//oligopeptide transport;GO:0045184//establishment of protein localization;GO:0015893//drug transport;GO:0006857//oligopeptide transport;GO:0045184//establishment of protein localization gi|225543357|ref|NP_067276.2|/0/solute carrier family 15 member 2 isoform 1 [Mus musculus] 236643 6557 0.01 0.01 0 - 0.080089511 Sytl5 synaptotagmin-like 5 K17598|1|0.0|1357|mmu:236643|synaptotagmin-like protein - GO:0043169//cation binding;GO:0017016//Ras GTPase binding;GO:0043169//cation binding;GO:0017016//Ras GTPase binding GO:0016192//vesicle-mediated transport;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0015031//protein transport "gi|148703722|gb|EDL35669.1|/0/synaptotagmin-like 5, isoform CRA_b, partial [Mus musculus]" 380683 3928 0.073333333 0.076666667 0.064130337 Up 0.080089511 Sec14l3 SEC14-like lipid binding 3 K17981|1|7e-142|508|fch:102055515|mitochondrial fission process protein 1;K16302|2|3e-140|502|tru:101066937|metal transporter CNNM;K01019|3|5e-29|133|umr:103681122|galactosylceramide sulfotransferase [EC:2.8.2.11];K12850|4|2e-13|81.3|tsp:Tsp_07066|pre-mRNA-splicing factor 38B;K19625|5|4e-10|70.5|pbi:103062952|retinaldehyde-binding protein 1 GO:0044464;GO:0031224//intrinsic component of membrane GO:0005488//binding - gi|71480138|ref|NP_001025108.1|/0/SEC14-like protein 3 [Mus musculus] 102688 2179 0.496666667 0.496666667 0 - 0.080089511 AU023762 expressed sequence AU023762 - - - - - 16524 3270 0.03 0.033333333 0.152003093 Up 0.080089511 Kcnj9 "potassium inwardly-rectifying channel, subfamily J, member 9" K05002|1|0.0|692|mmu:16524|potassium inwardly-rectifying channel subfamily J member 9 GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005242//inward rectifier potassium channel activity GO:0007267//cell-cell signaling;GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|675715442|ref|XP_008962539.1|/0/PREDICTED: G protein-activated inward rectifier potassium channel 3 isoform X1 [Pan paniscus] 217674 1614 0.036666667 0.033333333 -0.137503524 Down 0.080089511 Gphb5 glycoprotein hormone beta 5 K08521|1|2e-14|83.2|xma:102231029|luteinizing hormone beta polypeptide - - - - 16528 1757 0.06 0.056666667 -0.08246216 Down 0.080089511 Kcnk4 "potassium channel, subfamily K, member 4" K04915|1|3e-171|604|mmu:16528|potassium channel subfamily K member 4 GO:0016020//membrane GO:0005261//cation channel activity GO:0034220//ion transmembrane transport;GO:0030001//metal ion transport gi|569006483|ref|XP_006526781.1|/8.07857e-174/PREDICTED: potassium channel subfamily K member 4 isoform X4 [Mus musculus] 328440 997 0.056666667 0.056666667 0 - 0.080089511 Npm2 nucleophosmin/nucleoplasmin 2 K11277|1|2e-91|337|mmu:328440|nucleophosmin 2 GO:0031981//nuclear lumen;GO:0000785//chromatin;GO:0000229 GO:0005515//protein binding;GO:0097159//organic cyclic compound binding GO:0007275//multicellular organism development;GO:0003006//developmental process involved in reproduction;GO:0009566//fertilization;GO:0051259//protein oligomerization;GO:0007126//meiotic nuclear division;GO:0044093;GO:0007346//regulation of mitotic cell cycle;GO:0016568//chromatin modification;GO:0006260//DNA replication gi|254675203|ref|NP_851990.2|/1.86656e-90/nucleoplasmin-2 [Mus musculus] 320210 2935 0.27 0.273333333 0.017702002 Up 0.080089511 A230077H06Rik RIKEN cDNA A230077H06 gene - - - - - 329178 13533 0.01 0.01 0 - 0.080089511 Unc80 "unc-80, NALCN activator" - GO:0031224//intrinsic component of membrane - - gi|254939708|ref|NP_780719.2|/0/protein unc-80 homolog [Mus musculus] 74053 5219 0.036666667 0.033333333 -0.137503524 Down 0.080089511 Grip1 glutamate receptor interacting protein 1 K20251|1|0.0|1821|mmu:74053|glutamate receptor-interacting protein GO:0005768//endosome;GO:0044327//dendritic spine head;GO:0031982//vesicle;GO:0031090//organelle membrane;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0044425;GO:0005768//endosome;GO:0031982//vesicle;GO:0043005//neuron projection;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0044425;GO:0005768//endosome;GO:0031982//vesicle;GO:0043005//neuron projection;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0044425;GO:0005768//endosome;GO:0031982//vesicle;GO:0043005//neuron projection;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0044425;GO:0005768//endosome;GO:0044327//dendritic spine head;GO:0031982//vesicle;GO:0031090//organelle membrane;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0044425;GO:0005768//endosome;GO:0044327//dendritic spine head;GO:0031982//vesicle;GO:0031090//organelle membrane;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0044425 GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding;GO:0005515//protein binding GO:0048731//system development;GO:0045184//establishment of protein localization;GO:0048731//system development;GO:0045184//establishment of protein localization;GO:0048731//system development;GO:0045184//establishment of protein localization;GO:0048731//system development;GO:0045184//establishment of protein localization;GO:0048731//system development;GO:0045184//establishment of protein localization;GO:0048731//system development;GO:0045184//establishment of protein localization gi|568968795|ref|XP_006514300.1|/0/PREDICTED: glutamate receptor-interacting protein 1 isoform X7 [Mus musculus] 11997 1248 0.05 0.046666667 -0.099535674 Down 0.080089511 Akr1b7 "aldo-keto reductase family 1, member B7" K00011|1|2e-172|607|mmu:11997|aldehyde reductase [EC:1.1.1.21] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005501//retinoid binding;GO:0043168//anion binding;GO:0008106//alcohol dehydrogenase (NADP+) activity GO:0030647;GO:0006066//alcohol metabolic process;GO:0001523//retinoid metabolic process;GO:0016107 gi|160415215|ref|NP_033861.2|/1.7964e-171/aldose reductase-related protein 1 [Mus musculus] 330627 9129 0.033333333 0.03 -0.152003093 Down 0.080089511 Trim66 tripartite motif-containing 66 K12032|1|0.0|2251|mmu:330627|tripartite motif-containing protein 66 GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0043231//intracellular membrane-bounded organelle;GO:0044427;GO:0043231//intracellular membrane-bounded organelle;GO:0044427 GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding;GO:0046914//transition metal ion binding;GO:0042802//identical protein binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|284004881|ref|NP_001164383.1|/0/tripartite motif-containing protein 66 isoform 1 [Mus musculus] 110637 3488 0.02 0.02 0 - 0.080089511 Grik4 "glutamate receptor, ionotropic, kainate 4" "K05204|1|0.0|1868|mmu:110637|glutamate receptor, ionotropic kainate 4" GO:0043231//intracellular membrane-bounded organelle;GO:0033267;GO:0097060//synaptic membrane;GO:0043025//neuronal cell body;GO:0008328//ionotropic glutamate receptor complex GO:0004970//ionotropic glutamate receptor activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity GO:0007215//glutamate receptor signaling pathway;GO:0048545//response to steroid hormone;GO:0007267//cell-cell signaling;GO:0044765//single-organism transport "gi|304766513|ref|NP_780690.2|/0/glutamate receptor ionotropic, kainate 4 precursor [Mus musculus]" 14616 6989 0.02 0.023333333 0.222392421 Up 0.080089511 Gja8 "gap junction protein, alpha 8" "K07617|1|0.0|775|mmu:14616|gap junction protein, alpha 8" GO:0005921//gap junction;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0022829//wide pore channel activity GO:0043010//camera-type eye development;GO:0051259//protein oligomerization;GO:0007154//cell communication gi|6680009|ref|NP_032149.1|/0/gap junction alpha-8 protein [Mus musculus] 16177 4774.37 3.113333333 3.11 -0.001545469 Down 0.080089511 Il1r1 "interleukin 1 receptor, type I" K04386|1|0.0|1189|mmu:16177|interleukin 1 receptor type I GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0044327//dendritic spine head;GO:0044421;GO:0032991//macromolecular complex;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0044327//dendritic spine head;GO:0044421 GO:0004908//interleukin-1 receptor activity;GO:0070851//growth factor receptor binding;GO:0019899//enzyme binding;GO:0035254//glutamate receptor binding;GO:0004908//interleukin-1 receptor activity;GO:0070851//growth factor receptor binding;GO:0019899//enzyme binding;GO:0035254//glutamate receptor binding GO:0006952//defense response;GO:0000302//response to reactive oxygen species;GO:0001678//cellular glucose homeostasis;GO:0007292//female gamete generation;GO:0019221//cytokine-mediated signaling pathway;GO:0002376//immune system process;GO:0006952//defense response;GO:0000302//response to reactive oxygen species;GO:0001678//cellular glucose homeostasis;GO:0007292//female gamete generation;GO:0019221//cytokine-mediated signaling pathway;GO:0002376//immune system process gi|6680417|ref|NP_032388.1|/0/interleukin-1 receptor type 1 isoform 1 precursor [Mus musculus] 665194 1519 0.04 0.036666667 -0.125530882 Down 0.080089511 Gm7538 predicted gene 7538 - - - - - 23873 1032 2.716666667 2.72 0.001769093 Up 0.080089511 Faim Fas apoptotic inhibitory molecule - - - GO:0010720//positive regulation of cell development;GO:0006915//apoptotic process;GO:0010720//positive regulation of cell development;GO:0006915//apoptotic process gi|171184430|ref|NP_001116323.1|/4.57782e-103/fas apoptotic inhibitory molecule 1 Faim-L [Mus musculus] 105242658 253 0.223333333 0.226666667 0.021373651 Up 0.080089511 Hotairm1 "Hoxa transcript antisense RNA, myeloid-specific 1" - - - - - 26437 2126 0.053333333 0.05 -0.093109404 Down 0.080089511 Psg17 pregnancy specific glycoprotein 17 K06499|1|2e-117|426|mmu:384557|carcinoembryonic antigen-related cell adhesion molecule - GO:0005515//protein binding GO:0001525//angiogenesis;GO:0044703;GO:0038044;GO:0002376//immune system process;GO:0010467//gene expression;GO:0009690//cytokinin metabolic process;GO:0032653 gi|6679495|ref|NP_031703.1|/0/pregnancy specific glycoprotein 17 [Mus musculus] 21417 5806 7.166666667 7.163333333 -0.000671177 Down 0.080089511 Zeb1 zinc finger E-box binding homeobox 1 K09299|1|0.0|1840|mmu:21417|zinc finger homeobox protein 1/2 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0043566//structure-specific DNA binding GO:0001501//skeletal system development;GO:0010463//mesenchymal cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0048562//embryonic organ morphogenesis;GO:0033077//T cell differentiation in thymus;GO:0031076//embryonic camera-type eye development;GO:0043200//response to amino acid;GO:0035239//tube morphogenesis;GO:0030855//epithelial cell differentiation;GO:0051145//smooth muscle cell differentiation;GO:0030182//neuron differentiation gi|6756073|ref|NP_035676.1|/0/zinc finger E-box-binding homeobox 1 [Mus musculus] 271844 3125 0.023333333 0.023333333 0 - 0.080089511 Pla2g4f "phospholipase A2, group IVF" K16342|1|0.0|1699|mmu:271844|cytosolic phospholipase A2 [EC:3.1.1.4] GO:0001726//ruffle;GO:0000323//lytic vacuole GO:0043169//cation binding;GO:0004623//phospholipase A2 activity GO:0006644//phospholipid metabolic process;GO:0046677//response to antibiotic;GO:0014070//response to organic cyclic compound;GO:0015909//long-chain fatty acid transport gi|67972423|ref|NP_001019316.1|/0/cytosolic phospholipase A2 zeta [Mus musculus] 327978 5989 10.10666667 10.11 0.000475744 Up 0.080089511 Slfn5 schlafen 5 - GO:0043231//intracellular membrane-bounded organelle GO:0032550 GO:0048869//cellular developmental process "gi|148683739|gb|EDL15686.1|/0/schlafen 5, isoform CRA_a, partial [Mus musculus]" 790911 3627 0.013333333 0.016666667 0.321928095 Up 0.080089511 Slc13a2os "solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2, opposite strand" "K14445|1|4e-51|206|mmu:20500|solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity GO:0030001//metal ion transport;GO:0044763 "gi|148683622|gb|EDL15569.1|/1.49294e-117/mCG146185, partial [Mus musculus]" 14658 2979 0.023333333 0.023333333 0 - 0.080089511 Glrb "glycine receptor, beta subunit" K05196|1|0.0|879|mmu:14658|glycine receptor beta GO:0097060//synaptic membrane;GO:0034702//ion channel complex;GO:0097060//synaptic membrane;GO:0034702//ion channel complex GO:0005253//anion channel activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0016597//amino acid binding;GO:0005253//anion channel activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0016597//amino acid binding GO:0048731//system development;GO:0007338//single fertilization;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007270//neuron-neuron synaptic transmission;GO:0015698//inorganic anion transport;GO:0050953//sensory perception of light stimulus;GO:0060004//reflex;GO:0051259//protein oligomerization;GO:0006873//cellular ion homeostasis;GO:0008344//adult locomotory behavior;GO:0048731//system development;GO:0007338//single fertilization;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007270//neuron-neuron synaptic transmission;GO:0015698//inorganic anion transport;GO:0050953//sensory perception of light stimulus;GO:0060004//reflex;GO:0051259//protein oligomerization;GO:0006873//cellular ion homeostasis;GO:0008344//adult locomotory behavior gi|31981754|ref|NP_034428.2|/0/glycine receptor subunit beta isoform 1 precursor [Mus musculus] 16634 1303 0.046666667 0.046666667 0 - 0.080089511 Klra3 "killer cell lectin-like receptor, subfamily A, member 3" K10074|1|1e-14|83.2|ocu:100339146|C-type lectin domain family 7 member A;K10069|2|3e-14|82.0|myb:106725970|C-type lectin domain family 1 member A;K17517|3|2e-13|79.7|ocu:100342539|C-type lectin domain family 12 member B GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0051707//response to other organism;GO:0022610;GO:0051707//response to other organism;GO:0022610;GO:0051707//response to other organism;GO:0022610 gi|133922593|ref|NP_034778.2|/2.60121e-152/killer cell lectin-like receptor 3 [Mus musculus] 72826 3672 2.046666667 2.046666667 0 - 0.080089511 Fam76b "family with sequence similarity 76, member B" K20394|1|4e-106|389|fab:101820249|sestrin 2 GO:0043231//intracellular membrane-bounded organelle - - gi|28849885|ref|NP_789806.1|/3.3312e-157/protein FAM76B [Mus musculus] 12810 2484 0.043333333 0.04 -0.115477217 Down 0.080089511 Coch cochlin "K06238|1|3e-47|192|lcm:102347619|collagen, type VI, alpha" - - - - 667572 1206 0.046666667 0.046666667 0 - 0.080089511 Gm8709 glyceraldehyde-3-phosphate dehydrogenase pseudogene K00134|1|4e-146|285|mmu:14433|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] GO:0032991//macromolecular complex;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031988//membrane-bounded vesicle;GO:0005856//cytoskeleton;GO:0044444//cytoplasmic part "GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0000166//nucleotide binding;GO:0016769//transferase activity, transferring nitrogenous groups;GO:0015631//tubulin binding" GO:0007010//cytoskeleton organization;GO:0070997//neuron death;GO:0031647//regulation of protein stability;GO:0012501//programmed cell death;GO:0006412//translation;GO:0006007//glucose catabolic process;GO:0018119//peptidyl-cysteine S-nitrosylation;GO:0044710;GO:1901698//response to nitrogen compound;GO:0034341//response to interferon-gamma;GO:0032502//developmental process gi|576080555|ref|NP_001276655.1|/3.51298e-148/glyceraldehyde-3-phosphate dehydrogenase isoform 1 [Mus musculus] 67295 8500 0.07 0.07 0 - 0.080089511 Rab3c "RAB3C, member RAS oncogene family" K07883|1|3e-119|434|mmu:67295|Ras-related protein Rab-3C GO:0030136//clathrin-coated vesicle;GO:0016020//membrane GO:0032550 GO:0035556//intracellular signal transduction;GO:0045184//establishment of protein localization;GO:0006887//exocytosis;GO:0001505//regulation of neurotransmitter levels gi|537215752|gb|ERE81765.1|/2.40366e-131/ras-related protein Rab-3C-like protein [Cricetulus griseus] 15558 2971 0.023333333 0.023333333 0 - 0.080089511 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A K04157|1|0.0|907|mmu:15558|5-hydroxytryptamine receptor 2 GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0044444//cytoplasmic part GO:0004629//phospholipase C activity;GO:0008227//G-protein coupled amine receptor activity;GO:0005515//protein binding;GO:0043176//amine binding;GO:0043169//cation binding "GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019229//regulation of vasoconstriction;GO:0043405//regulation of MAP kinase activity;GO:0048871//multicellular organismal homeostasis;GO:0046474//glycerophospholipid biosynthetic process;GO:0035249//synaptic transmission, glutamatergic;GO:0007611//learning or memory;GO:0007600//sensory perception;GO:0048015//phosphatidylinositol-mediated signaling;GO:0006936//muscle contraction;GO:0032959//inositol trisphosphate biosynthetic process;GO:0042221//response to chemical;GO:0051283//negative regulation of sequestering of calcium ion;GO:0006813//potassium ion transport;GO:0008283//cell proliferation;GO:0046889//positive regulation of lipid biosynthetic process;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0044767//single-organism developmental process" gi|27753985|ref|NP_766400.1|/0/5-hydroxytryptamine receptor 2A [Mus musculus] 54392 3698 0.123333333 0.126666667 0.038474148 Up 0.080089511 Ncapg "non-SMC condensin I complex, subunit G" K06678|1|0.0|1886|mmu:54392|condensin complex subunit 3 - - - gi|169234780|ref|NP_062311.1|/0/condensin complex subunit 3 [Mus musculus] 63830 83437 0.8 0.803333333 0.005998741 Up 0.080089511 Kcnq1ot1 KCNQ1 overlapping transcript 1 K19941|1|5e-52|214|lcm:102351696|synapsin;K04534|4|2e-37|122|lcm:102363494|guanine nucleotide-binding protein G(o) subunit alpha - - - - 76071 2382 0.026666667 0.026666667 0 - 0.080089511 Jakmip1 janus kinase and microtubule interacting protein 1 K20478|1|2e-61|240|sko:100376626|golgin subfamily B member 1;K10362|2|1e-10|71.6|ocu:100343337|myosin XVIII GO:0044425;GO:0032991//macromolecular complex;GO:0015630//microtubule cytoskeleton GO:0003676//nucleic acid binding;GO:0015631//tubulin binding;GO:0005102//receptor binding;GO:0019899//enzyme binding GO:0045184//establishment of protein localization gi|148705573|gb|EDL37520.1|/0/janus kinase and microtubule interacting protein 1 [Mus musculus] 227058 12318 0.033333333 0.033333333 0 - 0.080089511 Dnah7b "dynein, axonemal, heavy chain 7B" "K10408|1|0.0|7910|mmu:227058|dynein heavy chain, axonemal" - - - "gi|237874196|ref|NP_001153858.1|/0/dynein, axonemal, heavy chain 7B [Mus musculus]" 19152 983 0.056666667 0.056666667 0 - 0.080089511 Prtn3 proteinase 3 K01350|1|3e-139|496|mmu:19152|myeloblastin [EC:3.4.21.76];K01334|4|2e-110|400|ngi:103737401|component factor D [EC:3.4.21.46] GO:0044444//cytoplasmic part;GO:0016020//membrane GO:0004175//endopeptidase activity;GO:0005515//protein binding GO:0006909//phagocytosis;GO:0097028//dendritic cell differentiation;GO:0019538//protein metabolic process;GO:0032963//collagen metabolic process gi|31981542|ref|NP_035308.2|/2.35323e-138/myeloblastin precursor [Mus musculus] 269198 12108 0.7 0.696666667 -0.006886386 Down 0.080089511 Nbeal1 neurobeachin like 1 K18953|1|8e-97|360|nve:NEMVE_v1g161851|factor associated with neutral sphingomyelinase activation - - - gi|153791557|ref|NP_775620.2|/0/neurobeachin-like protein 1 [Mus musculus] 226413 6174 0.016666667 0.013333333 -0.321928095 Down 0.080089511 Lct lactase K01229|1|0.0|3922|mmu:226413|lactase-phlorizin hydrolase [EC:3.2.1.108 3.2.1.62] GO:0044459;GO:0031224//intrinsic component of membrane;GO:0042995//cell projection "GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds" GO:0048545//response to steroid hormone;GO:0031667//response to nutrient levels;GO:0097305//response to alcohol;GO:0006950//response to stress;GO:0010039//response to iron ion;GO:0044238//primary metabolic process;GO:0034285 gi|124487297|ref|NP_001074547.1|/0/lactase-phlorizin hydrolase preproprotein [Mus musculus] 330166 8716 0.013333333 0.013333333 0 - 0.080089511 Miat myocardial infarction associated transcript (non-protein coding) - - - - - 14858 855 0.326666667 0.326666667 3.20E-16 Up 0.080089511 Gsta2 "glutathione S-transferase, alpha 2 (Yc2)" K00799|1|4e-116|419|mmu:14858|glutathione S-transferase [EC:2.5.1.18] GO:0031965//nuclear membrane;GO:0044444//cytoplasmic part "GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0072341//modified amino acid binding" GO:0006805//xenobiotic metabolic process;GO:0044767//single-organism developmental process gi|50263046|ref|NP_032208.2|/2.8609e-115/glutathione S-transferase A2 [Mus musculus] 76157 2629 0.026666667 0.023333333 -0.192645078 Down 0.080089511 Slc35d3 "solute carrier family 35, member D3" K15281|1|0.0|696|mmu:76157|solute carrier family 35 GO:0031224//intrinsic component of membrane - GO:0044765//single-organism transport gi|58037439|ref|NP_083805.1|/0/solute carrier family 35 member D3 [Mus musculus] 100504608 699 0.083333333 0.08 -0.058893689 Down 0.080089511 Mettl21b methyltransferase like 21B K02357|1|9e-106|384|pale:102895576|elongation factor Ts GO:0044464;GO:0031224//intrinsic component of membrane GO:0016741 - gi|326381089|ref|NP_001191965.1|/2.67025e-133/protein-lysine methyltransferase METTL21B [Mus musculus] 237029 3634 0.056666667 0.06 0.08246216 Up 0.080089511 4932411N23Rik RIKEN cDNA 4932411N23 gene K15225|1|2e-23|114|spu:100891604|transcription termination factor 1 - - - - 329509 1266 0.196666667 0.196666667 0 - 0.080089511 1810024B03Rik RIKEN cDNA 1810024B03 gene K19008|1|5e-81|254|cge:100770044|serine/threonine-protein kinase SIK1 [EC:2.7.11.1];K08798|3|2e-55|157|ngi:103733278|MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] - GO:0004672//protein kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process gi|38348502|ref|NP_941032.1|/1.12811e-112/uncharacterized protein LOC329509 [Mus musculus] 77767 3550 0.02 0.016666667 -0.263034406 Down 0.080089511 Ermn "ermin, ERM-like protein" K00710|1|3e-59|233|ssc:100627600|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0033267;GO:0043232;GO:0044297//cell body GO:0003779//actin binding GO:0022604//regulation of cell morphogenesis;GO:0030030//cell projection organization;GO:0030036//actin cytoskeleton organization gi|60360374|dbj|BAD90431.1|/1.1072e-141/mKIAA1189 protein [Mus musculus] 606736 4515 0.04 0.04 0 - 0.080089511 C920009B18Rik RIKEN cDNA C920009B18 gene K11290|1|3e-07|61.2|rno:317165|template-activating factor I - - - - 66991 1233 0.046666667 0.046666667 0 - 0.080089511 Khdc3 "KH domain containing 3, subcortical maternal complex member" K13911|1|2e-19|100|pon:100444154|basic salivary proline-rich protein 1/2;K10385|5|2e-17|93.6|mdo:100019077|loricrin - - - - 17910 7953 0.013333333 0.013333333 0 - 0.080089511 Myo15 myosin XV K10361|1|0.0|4502|mmu:17910|myosin XV GO:0015629//actin cytoskeleton;GO:0005902//microvillus;GO:0015629//actin cytoskeleton;GO:0005902//microvillus GO:0008092//cytoskeletal protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550;GO:0008092//cytoskeletal protein binding;GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0042471//ear morphogenesis;GO:0050954//sensory perception of mechanical stimulus;GO:0044708//single-organism behavior;GO:0042471//ear morphogenesis;GO:0050954//sensory perception of mechanical stimulus;GO:0044708//single-organism behavior gi|157041248|ref|NP_001096641.1|/0/unconventional myosin-XV isoform 3 [Mus musculus] 217262 6268 1.716666667 1.716666667 0 - 0.080089511 Abca9 "ATP-binding cassette, sub-family A (ABC1), member 9" "K05651|1|0.0|2911|mmu:217262|ATP-binding cassette, subfamily A (ABC1), member 9" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0009154//purine ribonucleotide catabolic process;GO:0051234//establishment of localization gi|153792543|ref|NP_671753.2|/0/ATP-binding cassette sub-family A member 9 [Mus musculus] 329152 11179 1.46 1.463333333 0.00329007 Up 0.080089511 Hecw2 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2" K12168|1|1e-159|564|mmu:329152|E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26] - - - gi|49457861|ref|NP_001001883.1|/0/E3 ubiquitin-protein ligase HECW2 isoform 1 [Mus musculus] 239759 3721 0.013333333 0.016666667 0.321928095 Up 0.080089511 Liph "lipase, member H" K19404|1|0.0|930|mmu:239759|phosphatidic acid-selective phospholipase A1 [EC:3.1.1.-] GO:0016020//membrane;GO:0044421;GO:0016020//membrane;GO:0044421;GO:0016020//membrane;GO:0044421;GO:0016020//membrane;GO:0044421 GO:0005539//glycosaminoglycan binding;GO:0016298//lipase activity;GO:0005539//glycosaminoglycan binding;GO:0016298//lipase activity;GO:0005539//glycosaminoglycan binding;GO:0016298//lipase activity;GO:0005539//glycosaminoglycan binding;GO:0016298//lipase activity GO:0006629//lipid metabolic process;GO:0006629//lipid metabolic process;GO:0006629//lipid metabolic process;GO:0006629//lipid metabolic process "gi|148665200|gb|EDK97616.1|/0/lipase, member H, isoform CRA_d, partial [Mus musculus]" 224907 2321 10.98333333 10.98666667 0.000437777 Up 0.080089511 Dus3l dihydrouridine synthase 3-like (S. cerevisiae) K05544|1|0.0|1278|mmu:224907|tRNA-dihydrouridine synthase 3 [EC:1.3.1.89] - "GO:0046914//transition metal ion binding;GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0000166//nucleotide binding" GO:0006399//tRNA metabolic process;GO:0044710 gi|255003775|ref|NP_659107.2|/0/tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like [Mus musculus] 68054 3690 0.043333333 0.043333333 0 - 0.080089511 Serpina12 "serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12" "K04525|1|0.0|803|mmu:68054|serpin peptidase inhibitor, clade A" - - - gi|13386038|ref|NP_080811.1|/0/serpin A12 precursor [Mus musculus] 328906 2977 0.246666667 0.25 0.019365325 Up 0.080089511 Gm15328 predicted gene 15328 - - - - - 227325 3664 0.02 0.02 0 - 0.080089511 Dner delta/notch-like EGF repeat containing K02599|1|1e-89|334|tca:661022|Notch GO:0031224//intrinsic component of membrane;GO:0043005//neuron projection;GO:0044297//cell body;GO:0005768//endosome GO:0046872//metal ion binding;GO:0005102//receptor binding;GO:0038023//signaling receptor activity GO:0016477//cell migration;GO:0016192//vesicle-mediated transport;GO:0044267//cellular protein metabolic process;GO:0007519//skeletal muscle tissue development;GO:0007399//nervous system development;GO:0007166//cell surface receptor signaling pathway;GO:0030154//cell differentiation gi|23097346|ref|NP_690879.1|/0/delta and Notch-like epidermal growth factor-related receptor precursor [Mus musculus] 100303744 3547 0.02 0.023333333 0.222392421 Up 0.080089511 Sprr2a2 small proline-rich protein 2A2 K02889|1|2e-41|87.0|oas:101115288|large subunit ribosomal protein L21e GO:0015934//large ribosomal subunit GO:0005198//structural molecule activity GO:0010467//gene expression "gi|148704804|gb|EDL36751.1|/2.02759e-41/mCG12076, partial [Mus musculus]" 18549 4766 0.016666667 0.016666667 0 - 0.080089511 Pcsk2 proprotein convertase subtilisin/kexin type 2 K01360|1|0.0|1289|mmu:18549|proprotein convertase subtilisin/kexin type 2 [EC:3.4.21.94] - - - gi|74179798|dbj|BAE36477.1|/0/unnamed protein product [Mus musculus] 320163 2987 0.036666667 0.033333333 -0.137503524 Down 0.080089511 4930525G20Rik RIKEN cDNA 4930525G20 gene - - - - "gi|148678336|gb|EDL10283.1|/1.39816e-49/mCG145153, partial [Mus musculus]" 22157 2012 0.033333333 0.03 -0.152003093 Down 0.080089511 Tulp1 tubby like protein 1 K19600|1|0.0|853|mmu:22157|tubby-related protein 1 GO:0044424;GO:0016020//membrane GO:0043168//anion binding;GO:0004930//G-protein coupled receptor activity;GO:0003779//actin binding GO:0043010//camera-type eye development;GO:0009583//detection of light stimulus;GO:0006909//phagocytosis;GO:0031175//neuron projection development;GO:0007601//visual perception;GO:0007166//cell surface receptor signaling pathway;GO:0001754//eye photoreceptor cell differentiation "gi|148690627|gb|EDL22574.1|/0/tubby like protein 1, isoform CRA_a, partial [Mus musculus]" 100503043 9014 0.486666667 0.49 0.009847786 Up 0.080089511 Armcx4 "armadillo repeat containing, X-linked 4" K11657|1|2e-12|79.3|obi:106877384|remodeling and spacing factor 1;K10385|2|2e-09|69.7|rno:502541|loricrin;K14000|5|2e-09|69.7|mmu:81910|ribosome-binding protein 1 - - - gi|363989837|ref|NP_001189429.2|/0/armadillo repeat-containing X-linked protein 4 [Mus musculus] 16531 6020 0.046666667 0.046666667 0 - 0.080089511 Kcnma1 "potassium large conductance calcium-activated channel, subfamily M, alpha member 1" K04936|1|0.0|2215|cjc:100402638|potassium large conductance calcium-activated channel subfamily M alpha member 1 GO:0009986//cell surface;GO:0031090//organelle membrane;GO:0033267;GO:0032991//macromolecular complex;GO:0042734//presynaptic membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0009986//cell surface;GO:0033267;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0031090//organelle membrane;GO:0033267;GO:0032991//macromolecular complex;GO:0042734//presynaptic membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane;GO:0044444//cytoplasmic part;GO:0044297//cell body GO:0036094//small molecule binding;GO:0042802//identical protein binding;GO:0015269//calcium-activated potassium channel activity;GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding;GO:0015269//calcium-activated potassium channel activity;GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding;GO:0036094//small molecule binding;GO:0036094//small molecule binding;GO:0042802//identical protein binding;GO:0015269//calcium-activated potassium channel activity;GO:0008092//cytoskeletal protein binding;GO:0043169//cation binding GO:0021700//developmental maturation;GO:0006915//apoptotic process;GO:0009628//response to abiotic stimulus;GO:0050954//sensory perception of mechanical stimulus;GO:0006884//cell volume homeostasis;GO:0042311//vasodilation;GO:0001508//action potential;GO:0030001//metal ion transport;GO:0051260//protein homooligomerization;GO:0007589//body fluid secretion;GO:0010565//regulation of cellular ketone metabolic process;GO:0034220//ion transmembrane transport;GO:0008344//adult locomotory behavior;GO:0048511//rhythmic process;GO:0010038//response to metal ion;GO:0048545//response to steroid hormone;GO:0007267//cell-cell signaling;GO:0003014//renal system process;GO:0060004//reflex;GO:0006950//response to stress;GO:0050905//neuromuscular process;GO:0006875//cellular metal ion homeostasis;GO:0060113//inner ear receptor cell differentiation;GO:0014832//urinary bladder smooth muscle contraction;GO:0007599//hemostasis;GO:0007267//cell-cell signaling;GO:0010565//regulation of cellular ketone metabolic process;GO:0001508//action potential;GO:0030001//metal ion transport;GO:0006884//cell volume homeostasis;GO:0007589//body fluid secretion;GO:0060113//inner ear receptor cell differentiation;GO:0010033//response to organic substance;GO:0003014//renal system process;GO:0006915//apoptotic process;GO:0042311//vasodilation;GO:0021700//developmental maturation;GO:0060004//reflex;GO:0050954//sensory perception of mechanical stimulus;GO:0051259//protein oligomerization;GO:0010038//response to metal ion;GO:0006950//response to stress;GO:0014832//urinary bladder smooth muscle contraction;GO:0006875//cellular metal ion homeostasis;GO:0050905//neuromuscular process;GO:0008344//adult locomotory behavior;GO:0021700//developmental maturation;GO:0006915//apoptotic process;GO:0009628//response to abiotic stimulus;GO:0050954//sensory perception of mechanical stimulus;GO:0006884//cell volume homeostasis;GO:0042311//vasodilation;GO:0001508//action potential;GO:0030001//metal ion transport;GO:0051260//protein homooligomerization;GO:0007589//body fluid secretion;GO:0010565//regulation of cellular ketone metabolic process;GO:0034220//ion transmembrane transport;GO:0008344//adult locomotory behavior;GO:0048511//rhythmic process;GO:0010038//response to metal ion;GO:0048545//response to steroid hormone;GO:0007267//cell-cell signaling;GO:0003014//renal system process;GO:0060004//reflex;GO:0006950//response to stress;GO:0050905//neuromuscular process;GO:0006875//cellular metal ion homeostasis;GO:0060113//inner ear receptor cell differentiation;GO:0014832//urinary bladder smooth muscle contraction gi|358438073|ref|NP_001240303.1|/0/calcium-activated potassium channel subunit alpha-1 isoform 18 [Mus musculus] 13813 3674 0.116666667 0.113333333 -0.041820176 Down 0.080089511 Eomes eomesodermin K10173|1|0.0|1113|mmu:13813|eomesodermin protein - - - - 83762 6862 0.01 0.013333333 0.415037499 Up 0.080089511 Otof otoferlin K19949|1|0.0|3687|mmu:83762|otoferlin GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle;GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle;GO:0031224//intrinsic component of membrane;GO:0008021//synaptic vesicle GO:0005488//binding;GO:0005488//binding;GO:0005488//binding GO:0050954//sensory perception of mechanical stimulus;GO:0006887//exocytosis;GO:0050954//sensory perception of mechanical stimulus;GO:0006887//exocytosis;GO:0050954//sensory perception of mechanical stimulus;GO:0006887//exocytosis gi|556695426|ref|NP_001273350.1|/0/otoferlin isoform 3 [Mus musculus] 13508 7481 0.013333333 0.01 -0.415037499 Down 0.080089511 Dscam Down syndrome cell adhesion molecule K06767|1|0.0|3861|mmu:13508|Down syndrome cell adhesion molecule GO:0043005//neuron projection;GO:0016021//integral component of membrane GO:0005488//binding GO:0016358//dendrite development;GO:0007155//cell adhesion;GO:0008038//neuron recognition;GO:0016310//phosphorylation;GO:0009886//post-embryonic morphogenesis;GO:0045773//positive regulation of axon extension;GO:0044708//single-organism behavior gi|13626028|ref|NP_112451.1|/0/Down syndrome cell adhesion molecule homolog precursor [Mus musculus] 26945 1217 0.086666667 0.086666667 0 - 0.080089511 Tpsg1 tryptase gamma 1 K09615|1|3e-166|587|mmu:26945|tryptase gamma 1 [EC:3.4.21.-] GO:0016021//integral component of membrane GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|255683445|ref|NP_036164.2|/2.42632e-165/tryptase gamma precursor [Mus musculus] 545055 947 0.013333333 0.01 -0.415037499 Down 0.080089511 Cma2 "chymase 2, mast cell" K01329|1|5e-90|333|cge:100756053|chymase [EC:3.4.21.39];K08661|2|4e-89|330|mmu:17224|mast cell peptidase 1 [EC:3.4.21.-];K08662|4|1e-85|318|rno:29266|mast cell peptidase 2 [EC:3.4.21.-] GO:0044464 GO:0005539//glycosaminoglycan binding;GO:0033218//amide binding;GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|67010053|ref|NP_001019885.1|/3.66651e-133/mast cell protease 10 precursor [Mus musculus] 18488 5183 0.06 0.063333333 0.078002512 Up 0.080089511 Cntn3 contactin 3 K06761|1|0.0|2019|mmu:18488|contactin 3 GO:0031225//anchored component of membrane - GO:0048731//system development;GO:0007155//cell adhesion gi|117938277|ref|NP_032805.2|/0/contactin-3 precursor [Mus musculus] 237213 2775 0.023333333 0.023333333 0 - 0.080089511 Glra2 "glycine receptor, alpha 2 subunit" K05194|1|0.0|831|mmu:237213|glycine receptor alpha-2 GO:0097060//synaptic membrane;GO:0034702//ion channel complex GO:0005253//anion channel activity;GO:0016597//amino acid binding;GO:0005237//inhibitory extracellular ligand-gated ion channel activity GO:0007399//nervous system development;GO:0015698//inorganic anion transport;GO:0007186//G-protein coupled receptor signaling pathway "gi|148708798|gb|EDL40745.1|/0/glycine receptor, alpha 2 subunit, isoform CRA_a, partial [Mus musculus]" 20670 1156 0.05 0.05 0 - 0.080089511 Sox15 SRY (sex determining region Y)-box 15 K09271|1|2e-114|414|mmu:20670|transcription factor SOX15/30 GO:0043231//intracellular membrane-bounded organelle GO:0003676//nucleic acid binding GO:0045445//myoblast differentiation;GO:0014706//striated muscle tissue development;GO:0042246//tissue regeneration;GO:0006366//transcription from RNA polymerase II promoter gi|22094091|ref|NP_033261.1|/1.52383e-113/protein SOX-15 [Mus musculus] 93873 2789 0.023333333 0.02 -0.222392421 Down 0.080089511 Pcdhb2 protocadherin beta 2 K16494|1|0.0|1443|mmu:93873|protocadherin beta GO:0031224//intrinsic component of membrane - GO:0016337//single organismal cell-cell adhesion gi|16716427|ref|NP_444357.1|/0/protocadherin beta-2 [Mus musculus] 12263 2644 0.413333333 0.413333333 0 - 0.080089511 C2 complement component 2 (within H-2S) K01332|1|0.0|1493|mmu:12263|complement component 2 [EC:3.4.21.43] - - - - 319574 627 0.163333333 0.163333333 -3.20E-16 Down 0.080089511 Gm20735 "predicted gene, 20735" - - - - - 239188 3549 0.26 0.26 0 - 0.080089511 Enox1 ecto-NOX disulfide-thiol exchanger 1 - GO:0016020//membrane GO:0003824//catalytic activity;GO:0097159//organic cyclic compound binding GO:0044710;GO:0051234//establishment of localization;GO:0006091//generation of precursor metabolites and energy gi|672028764|ref|XP_008768296.1|/0/PREDICTED: ecto-NOX disulfide-thiol exchanger 1 isoform X3 [Rattus norvegicus] 270599 1040 0.053333333 0.053333333 0 - 0.080089511 Gm648 predicted gene 648 K13180|1|1e-26|122|lve:103070659|ATP-dependent RNA helicase DDX26B [EC:3.6.4.-] - - - gi|755565444|ref|XP_011245900.1|/1.68979e-121/PREDICTED: uncharacterized protein LOC270599 isoform X2 [Mus musculus] 237542 7128.46 4.886666667 4.89 0.000983768 Up 0.080089511 Osbpl8 oxysterol binding protein-like 8 K20464|1|0.0|1688|mmu:237542|oxysterol-binding protein-related protein 5/8 - GO:0032934//sterol binding;GO:0032934//sterol binding GO:0010888//negative regulation of lipid storage;GO:0051234//establishment of localization;GO:0030154//cell differentiation;GO:0010888//negative regulation of lipid storage;GO:0051234//establishment of localization;GO:0030154//cell differentiation gi|51243034|ref|NP_780698.2|/0/oxysterol-binding protein-related protein 8 isoform a [Mus musculus] 13411 14072 0.013333333 0.01 -0.415037499 Down 0.080089511 Dnah11 "dynein, axonemal, heavy chain 11" "K10408|1|0.0|8685|mmu:13411|dynein heavy chain, axonemal" - - - "gi|393794754|ref|NP_034190.3|/0/dynein heavy chain 11, axonemal [Mus musculus]" 15425 1592 0.063333333 0.066666667 0.074000581 Up 0.080089511 Hoxc6 homeobox C6 K09306|1|3e-115|418|pale:102887961|homeobox protein HoxA/B/C6 GO:0043231//intracellular membrane-bounded organelle GO:0003712//transcription cofactor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding GO:0003002//regionalization;GO:0001501//skeletal system development;GO:0006366//transcription from RNA polymerase II promoter gi|4758554|ref|NP_004494.1|/2.17262e-114/homeobox protein Hox-C6 isoform 1 [Homo sapiens] 545655 549 0.01 0.013333333 0.415037499 Up 0.080089511 Gm13287 predicted gene 13287 K05414|1|1e-38|160|cge:100763520|interferon alpha GO:0044421 GO:0005102//receptor binding GO:0007166//cell surface receptor signaling pathway;GO:0030098//lymphocyte differentiation;GO:0002252;GO:0007049//cell cycle;GO:0012501//programmed cell death gi|239050335|ref|NP_001155080.1|/2.85832e-102/interferon zeta-like precursor [Mus musculus] 171463 8220 1.33 1.326666667 -0.003620316 Down 0.080089511 Il17rd interleukin 17 receptor D K05167|1|0.0|1417|mmu:171463|interleukin 17 receptor D GO:0012505//endomembrane system;GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding - gi|24025662|ref|NP_602319.1|/0/interleukin-17 receptor D precursor [Mus musculus] 13835 3273 0.426666667 0.43 0.011227255 Up 0.080089511 Epha1 Eph receptor A1 K05102|1|0.0|1855|mmu:13835|Eph receptor A1 [EC:2.7.10.1] GO:0016021//integral component of membrane GO:0019900//kinase binding;GO:0005003//ephrin receptor activity;GO:0032550 GO:0001952//regulation of cell-matrix adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001933//negative regulation of protein phosphorylation;GO:0016477//cell migration;GO:0000904//cell morphogenesis involved in differentiation;GO:0008283//cell proliferation;GO:0032233//positive regulation of actin filament bundle assembly;GO:0001525//angiogenesis gi|31980651|ref|NP_076069.2|/0/ephrin type-A receptor 1 precursor [Mus musculus] 244416 4229 4.183333333 4.18 -0.001150016 Down 0.080089511 Ppp1r3b "protein phosphatase 1, regulatory (inhibitor) subunit 3B" K07189|1|6e-165|584|mmu:244416|protein phosphatase 1 regulatory subunit 3A/B/C/D/E GO:0043227//membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0016791//phosphatase activity;GO:0005515//protein binding;GO:0019208//phosphatase regulator activity GO:0005980//glycogen catabolic process;GO:0019222//regulation of metabolic process;GO:0005978//glycogen biosynthetic process "gi|37805233|gb|AAH60261.1|/7.57001e-169/Ppp1r3b protein, partial [Mus musculus]" 240479 2153 0.03 0.026666667 -0.169925001 Down 0.080089511 Fam69c "family with sequence similarity 69, member C" K18660|1|2e-14|83.6|isc:IscW_ISCW011807|malonyl-CoA/methylmalonyl-CoA synthetase [EC:6.2.1.-] - - - gi|569005321|ref|XP_006526536.1|/4.6903e-166/PREDICTED: protein FAM69C isoform X4 [Mus musculus] 16963 502 0.11 0.106666667 -0.044394119 Down 0.080089511 Xcl1 chemokine (C motif) ligand 1 K05507|1|3e-42|172|mmu:16963|C motif chemokine 1/2 GO:0044421 GO:0005125//cytokine activity;GO:0042802//identical protein binding;GO:0001664//G-protein coupled receptor binding "GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0006954//inflammatory response;GO:0072679//thymocyte migration;GO:0070670//response to interleukin-4;GO:0002726//positive regulation of T cell cytokine production;GO:0031349//positive regulation of defense response;GO:0006351//transcription, DNA-templated;GO:0035711//T-helper 1 cell activation;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0002418//immune response to tumor cell;GO:0035739;GO:0002426//immunoglobulin production in mucosal tissue;GO:0051283//negative regulation of sequestering of calcium ion;GO:0044092//negative regulation of molecular function;GO:0035747//natural killer cell chemotaxis;GO:0007154//cell communication;GO:0071363//cellular response to growth factor stimulus;GO:0035740//CD8-positive, alpha-beta T cell proliferation;GO:0001818//negative regulation of cytokine production;GO:0051707//response to other organism" gi|6678712|ref|NP_032536.1|/2.04186e-41/lymphotactin precursor [Mus musculus] 100043684 3723 0.04 0.036666667 -0.125530882 Down 0.080089511 Amy2a4 amylase 2a4 K01176|1|0.0|1090|mmu:100043688|alpha-amylase [EC:3.2.1.1] GO:0044421 GO:0046872//metal ion binding;GO:0043168//anion binding;GO:0016160//amylase activity GO:0005975//carbohydrate metabolic process "gi|148680466|gb|EDL12413.1|/0/mCG11265, isoform CRA_a, partial [Mus musculus]" 244646 6576 0.943333333 0.94 -0.00510689 Down 0.080089511 Pkd1l3 polycystic kidney disease 1 like 3 K04989|1|0.0|3486|mmu:244646|polycystin 1L3 GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464;GO:0031224//intrinsic component of membrane;GO:0044464 GO:0046872//metal ion binding;GO:0005216//ion channel activity;GO:0008527//taste receptor activity;GO:0046872//metal ion binding;GO:0005216//ion channel activity;GO:0008527//taste receptor activity;GO:0046872//metal ion binding;GO:0005216//ion channel activity;GO:0008527//taste receptor activity GO:0006811//ion transport;GO:0010447//response to acidic pH;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006811//ion transport;GO:0010447//response to acidic pH;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006811//ion transport;GO:0010447//response to acidic pH;GO:0007186//G-protein coupled receptor signaling pathway gi|115583681|ref|NP_001034789.2|/0/polycystic kidney disease protein 1-like 3 isoform a precursor [Mus musculus] 14186 3146 0.1 0.1 0 - 0.080089511 Fgfr4 fibroblast growth factor receptor 4 K05095|1|0.0|1439|mmu:14186|fibroblast growth factor receptor 4 [EC:2.7.10.1] GO:0031981//nuclear lumen;GO:0030054//cell junction;GO:0016021//integral component of membrane GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005539//glycosaminoglycan binding;GO:0032550;GO:0019838//growth factor binding GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0043085//positive regulation of catalytic activity;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048870//cell motility;GO:0032844//regulation of homeostatic process;GO:0043410//positive regulation of MAPK cascade;GO:0006508//proteolysis;GO:0060428//lung epithelium development;GO:0003156//regulation of organ formation;GO:0033500//carbohydrate homeostasis;GO:0072506;GO:0022617//extracellular matrix disassembly;GO:0008283//cell proliferation;GO:0006699//bile acid biosynthetic process;GO:0006468//protein phosphorylation gi|112293260|ref|NP_032037.2|/0/fibroblast growth factor receptor 4 precursor [Mus musculus] 107751 1550 0.063333333 0.063333333 0 - 0.080089511 Prrxl1 paired related homeobox protein-like 1 K09452|1|1e-25|120|mcf:102136734|homeobox protein aristaless-related GO:0043231//intracellular membrane-bounded organelle GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding "GO:0007600//sensory perception;GO:0021510//spinal cord development;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0021545//cranial nerve development;GO:0006935//chemotaxis;GO:0009266//response to temperature stimulus;GO:0006351//transcription, DNA-templated" gi|49169835|ref|NP_001001796.1|/2.23639e-116/dorsal root ganglia homeobox protein [Mus musculus] 12369 2350 5.043333333 5.043333333 0 - 0.080089511 Casp7 caspase 7 K04397|1|8e-170|600|mmu:12369|caspase 7 [EC:3.4.22.60] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0004175//endopeptidase activity GO:0012502//induction of programmed cell death;GO:0009416//response to light stimulus;GO:0043065//positive regulation of apoptotic process;GO:0051604//protein maturation;GO:0044767//single-organism developmental process gi|1894917|gb|AAC53068.1|/0/Lice2 cysteine protease [Mus musculus] 218865 5450 0.056666667 0.06 0.08246216 Up 0.080089511 Chdh choline dehydrogenase K00108|1|0.0|1245|mmu:218865|choline dehydrogenase [EC:1.1.99.1] GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0019866//organelle inner membrane "GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding;GO:0016614//oxidoreductase activity, acting on CH-OH group of donors;GO:0000166//nucleotide binding" GO:0019695//choline metabolic process;GO:0019695//choline metabolic process;GO:0019695//choline metabolic process "gi|148692803|gb|EDL24750.1|/0/choline dehydrogenase, partial [Mus musculus]" 108956 2044 0.03 0.026666667 -0.169925001 Down 0.080089511 Apol7c apolipoprotein L 7c K14480|1|4e-128|461|mmu:108956|apolipoprotein L - - - gi|30425100|ref|NP_780600.1|/3.09163e-127/apolipoprotein L 7c [Mus musculus] 14536 5874.36 0.28 0.283333333 0.017073513 Up 0.080089511 Nr6a1 "nuclear receptor subfamily 6, group A, member 1" K08561|1|0.0|902|hgl:101718322|germ cell nuclear factor GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0046914//transition metal ion binding;GO:0038023//signaling receptor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0042802//identical protein binding;GO:0003677//DNA binding GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0048869//cellular developmental process;GO:0048232//male gamete generation;GO:0006366//transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0048869//cellular developmental process;GO:0048232//male gamete generation gi|227116318|ref|NP_001153021.1|/0/nuclear receptor subfamily 6 group A member 1 isoform 3 [Mus musculus] 72669 1280 0.043333333 0.046666667 0.106915204 Up 0.080089511 2810032G03Rik RIKEN cDNA 2810032G03 gene - - - - - 639910 1427 0.043333333 0.043333333 0 - 0.080089511 Gm20767 "predicted gene, 20767" - - - - "gi|393532990|ref|NP_001034737.2|/1.03163e-96/2-cell-stage, variable group, member 1-like [Mus musculus] " 107372 2595 0.043333333 0.04 -0.115477217 Down 0.080089511 C030016D13Rik RIKEN cDNA C030016D13 gene - - - - gi|26338926|dbj|BAC33134.1|/7.92821e-62/unnamed protein product [Mus musculus] 67874 1460 0.04 0.04 0 - 0.080089511 Rprm "reprimo, TP53 dependent G2 arrest mediator candidate" "K10128|1|2e-54|215|mmu:67874|reprimo, TP53-dependent G2 arrest mediator candidate" GO:0044424;GO:0031224//intrinsic component of membrane - GO:0022402//cell cycle process;GO:0000278//mitotic cell cycle gi|12963661|ref|NP_075885.1|/1.90383e-53/protein reprimo [Mus musculus] 622924 1142 0.05 0.05 0 - 0.080089511 Gm6370 predicted gene 6370 K08732|1|4e-18|94.7|ptg:102965767|ral guanine nucleotide dissociation stimulator - - - gi|340805832|ref|NP_001230039.1|/1.16331e-166/predicted gene 6370 [Mus musculus] 240396 4080 3.123333333 3.126666667 0.001538875 Up 0.080089511 Mex3c mex3 RNA binding family member C K15686|1|0.0|816|mmu:240396|RNA-binding protein MEX3 [EC:2.3.2.27] GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0003824//catalytic activity - gi|158508713|ref|NP_001034303.3|/0/RNA-binding E3 ubiquitin-protein ligase MEX3C [Mus musculus] 57749 3944 0.03 0.026666667 -0.169925001 Down 0.080089511 Piwil1 piwi-like RNA-mediated gene silencing 1 K02156|1|0.0|1637|rno:363912|aubergine GO:0035770//ribonucleoprotein granule;GO:0034518//RNA cap binding complex GO:0003723//RNA binding GO:0006412//translation;GO:0016458//gene silencing;GO:0022403;GO:0048232//male gamete generation;GO:0034660//ncRNA metabolic process;GO:0007281//germ cell development "gi|148687585|gb|EDL19532.1|/0/piwi-like homolog 1 (Drosophila), isoform CRA_a, partial [Mus musculus]" 619312 2733 0.153333333 0.153333333 0 - 0.080089511 G730013B05Rik RIKEN cDNA G730013B05 gene - - - - - 16153 1306 0.043333333 0.043333333 0 - 0.080089511 Il10 interleukin 10 K05443|1|4e-93|344|mmu:16153|interleukin 10 - - - - 210801 9220 0.016666667 0.02 0.263034406 Up 0.080089511 Unc5d unc-5 netrin receptor D K07521|1|0.0|1887|mmu:210801|netrin receptor unc-5 GO:0044464;GO:0031224//intrinsic component of membrane - GO:0012501//programmed cell death;GO:0007154//cell communication;GO:0032502//developmental process gi|23346575|ref|NP_694775.1|/0/netrin receptor UNC5D precursor [Mus musculus] 242443 7667 0.013333333 0.01 -0.415037499 Down 0.080089511 Grin3a "glutamate receptor ionotropic, NMDA3A" "K05213|1|0.0|2140|rno:191573|glutamate receptor ionotropic, NMDA 3A" GO:0030313//cell envelope;GO:0008328//ionotropic glutamate receptor complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0044297//cell body;GO:0030313//cell envelope;GO:0008328//ionotropic glutamate receptor complex;GO:0044327//dendritic spine head;GO:0097060//synaptic membrane;GO:0044297//cell body GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004970//ionotropic glutamate receptor activity;GO:0016597//amino acid binding;GO:0005261//cation channel activity;GO:0019903//protein phosphatase binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0004970//ionotropic glutamate receptor activity;GO:0016597//amino acid binding;GO:0005261//cation channel activity;GO:0019903//protein phosphatase binding GO:0001964//startle response;GO:0006816//calcium ion transport;GO:0031175//neuron projection development;GO:0097305//response to alcohol;GO:0007215//glutamate receptor signaling pathway;GO:0001964//startle response;GO:0006816//calcium ion transport;GO:0031175//neuron projection development;GO:0097305//response to alcohol;GO:0007215//glutamate receptor signaling pathway "gi|166158134|ref|NP_001028523.1|/0/glutamate receptor ionotropic, NMDA 3A isoform 2 precursor [Mus musculus]" 319684 1636 0.093333333 0.096666667 0.050626073 Up 0.080089511 5031425F14Rik RIKEN cDNA 5031425F14 gene K13191|1|1e-10|70.5|pss:102459762|RNA-binding protein 16 - - - "gi|148674536|gb|EDL06483.1|/1.22499e-27/mCG1027940, partial [Mus musculus]" 277328 4263 0.02 0.016666667 -0.263034406 Down 0.080089511 Trpa1 "transient receptor potential cation channel, subfamily A, member 1" K04984|1|0.0|2283|mmu:277328|transient receptor potential cation channel subfamily A member 1 GO:0031224//intrinsic component of membrane;GO:0043232 GO:0005261//cation channel activity GO:0044763;GO:0000302//response to reactive oxygen species;GO:0019233//sensory perception of pain;GO:0050951//sensory perception of temperature stimulus;GO:0006816//calcium ion transport;GO:0033555//multicellular organismal response to stress "gi|148682385|gb|EDL14332.1|/0/transient receptor potential cation channel, subfamily A, member 1, isoform CRA_b, partial [Mus musculus]" 57349 1098 0.47 0.47 0 - 0.080089511 Ppbp pro-platelet basic protein K10029|1|1e-46|189|mmu:57349|platelet basic protein - - GO:0050896//response to stimulus;GO:0001775//cell activation;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0002376//immune system process gi|12963823|ref|NP_076274.1|/9.61763e-46/platelet basic protein precursor [Mus musculus] 217143 9276 0.016666667 0.013333333 -0.321928095 Down 0.080089511 Gpr179 G protein-coupled receptor 179 K08469|1|0.0|785|cmk:103185747|G protein-coupled receptor 158 - - - - 72315 1278 0.153333333 0.156666667 0.031026896 Up 0.080089511 Ccdc74a coiled-coil domain containing 74A K12353|1|2e-06|55.8|chx:102169580|sphingomyelin phosphodiesterase 4 [EC:3.1.4.12] - - - "gi|148665059|gb|EDK97475.1|/0/mCG131852, isoform CRA_c, partial [Mus musculus]" 319482 7922 0.01 0.013333333 0.415037499 Up 0.080089511 9530053A07Rik RIKEN cDNA 9530053A07 gene K18273|1|0.0|940|ola:101166341|alpha-tectorin - - - gi|257467625|ref|NP_001158127.1|/0/Fc fragment of IgG binding protein-like precursor [Mus musculus] 52389 4777 0.04 0.04 0 - 0.080089511 Adgra1 adhesion G protein-coupled receptor A1 K08460|1|0.0|1045|mmu:52389|G protein-coupled receptor 123 GO:0031224//intrinsic component of membrane - - gi|33991715|gb|AAH56493.1|/0/Gpr123 protein [Mus musculus] 20613 1633 3.143333333 3.143333333 3.20E-16 Up 0.080089511 Snai1 snail family zinc finger 1 K05707|1|3e-139|497|mmu:20613|snail 1 - - - - 237636 4571 0.14 0.14 -3.20E-16 Down 0.080089511 Npc1l1 NPC1-like 1 K14461|1|0.0|2357|mmu:237636|Niemann-Pick C1-like protein 1 GO:0031224//intrinsic component of membrane;GO:0005903//brush border;GO:0044459 GO:0004888//transmembrane signaling receptor activity;GO:0017016//Ras GTPase binding;GO:0017022//myosin binding GO:0055092//sterol homeostasis;GO:0030301//cholesterol transport;GO:0019538//protein metabolic process;GO:0042221//response to chemical;GO:0008203//cholesterol metabolic process gi|253970442|ref|NP_997125.2|/0/Niemann-Pick C1-like protein 1 precursor [Mus musculus] 235631 1455 0.043333333 0.04 -0.115477217 Down 0.080089511 Prss50 "protease, serine 50" K09629|1|9e-40|167|bta:528784|serine protease 33 [EC:3.4.21.-] GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle GO:0004175//endopeptidase activity GO:0019538//protein metabolic process gi|31981922|ref|NP_666339.2|/0/probable threonine protease PRSS50 precursor [Mus musculus] 12309 480 0.113333333 0.113333333 0 - 0.080089511 S100g S100 calcium binding protein G K14734|1|9e-38|157|mmu:12309|S100 calcium binding protein G GO:0044459 GO:0046872//metal ion binding;GO:0005496//steroid binding - gi|7106263|ref|NP_033919.1|/6.27937e-37/protein S100-G [Mus musculus] 19281 12126.6 0.033333333 0.036666667 0.137503524 Up 0.080089511 Ptprt "protein tyrosine phosphatase, receptor type, T" K13297|1|0.0|2761|mmu:19281|receptor-type tyrosine-protein phosphatase T [EC:3.1.3.48] - - - - 195208 6894 0.03 0.026666667 -0.169925001 Down 0.080089511 Dcdc2a doublecortin domain containing 2a K08805|1|2e-20|103|ola:101167140|doublecortin-like kinase 1/2 [EC:2.7.11.1];K16579|3|1e-19|100|bacu:103012693|neuronal migration protein doublecortin - - GO:0016358//dendrite development;GO:0006952//defense response;GO:0016477//cell migration;GO:0007165//signal transduction;GO:0016358//dendrite development;GO:0016477//cell migration;GO:0007165//signal transduction gi|307344655|ref|NP_001182546.1|/0/doublecortin domain-containing protein 2 isoform 2 [Mus musculus] 27405 3034 0.036666667 0.033333333 -0.137503524 Down 0.080089511 Abcg3 "ATP-binding cassette, sub-family G (WHITE), member 3" "K05682|1|0.0|1259|mmu:27405|ATP-binding cassette, subfamily G (WHITE), member 3;K05681|3|0.0|962|cge:100774296|ATP-binding cassette, subfamily G (WHITE), member 2" GO:0031224//intrinsic component of membrane GO:0017111//nucleoside-triphosphatase activity;GO:0032550 GO:0051234//establishment of localization gi|755512486|ref|XP_011247753.1|/0/PREDICTED: ATP-binding cassette sub-family G member 3 isoform X2 [Mus musculus] 246190 3673 0.02 0.016666667 -0.263034406 Down 0.080089511 Otoa otoancorin - GO:0044459;GO:0031224//intrinsic component of membrane;GO:0031012//extracellular matrix - GO:0050954//sensory perception of mechanical stimulus gi|21314862|ref|NP_647471.1|/0/otoancorin precursor [Mus musculus] 320051 9601 0.013333333 0.01 -0.415037499 Down 0.080089511 Exph5 exophilin 5 K17598|1|1e-09|70.1|aam:106482665|synaptotagmin-like protein GO:0043231//intracellular membrane-bounded organelle GO:0017016//Ras GTPase binding GO:0006887//exocytosis;GO:0009306//protein secretion gi|257796249|ref|NP_789816.2|/0/exophilin-5 [Mus musculus] 209032 6538 0.27 0.273333333 0.017702002 Up 0.080089511 Zc3hav1l "zinc finger CCCH-type, antiviral 1-like" K15259|1|4e-56|224|oaa:100089554|poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30] - GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding - gi|27369640|ref|NP_766055.1|/1.0232e-159/zinc finger CCCH-type antiviral protein 1-like [Mus musculus] 18626 4662.99 41.64333333 41.64333333 0 - 0.080089511 Per1 period circadian clock 1 K02633|1|0.0|1543|mmu:18626|period circadian protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding GO:0007623//circadian rhythm;GO:0006366//transcription from RNA polymerase II promoter;GO:0007623//circadian rhythm;GO:0006366//transcription from RNA polymerase II promoter gi|226823277|ref|NP_035195.2|/0/period circadian protein homolog 1 [Mus musculus] 140476 5757 0.016666667 0.013333333 -0.321928095 Down 0.080089511 Strc stereocilin - GO:0032421//stereocilium bundle;GO:0031513//nonmotile primary cilium - GO:0050954//sensory perception of mechanical stimulus;GO:0002093//auditory receptor cell morphogenesis gi|120300985|ref|NP_536707.2|/0/stereocilin precursor [Mus musculus] 18389 2386 0.026666667 0.026666667 0 - 0.080089511 Oprl1 opioid receptor-like 1 K04216|1|4e-64|248|mmu:18389|nociceptin receptor GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0016021//integral component of membrane;GO:0016021//integral component of membrane;GO:0031224//intrinsic component of membrane;GO:0016020//membrane GO:0004985//opioid receptor activity;GO:0004985//opioid receptor activity;GO:0004985//opioid receptor activity;GO:0004985//opioid receptor activity;GO:0004985//opioid receptor activity;GO:0004985//opioid receptor activity;GO:0004985//opioid receptor activity GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007186//G-protein coupled receptor signaling pathway;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007186//G-protein coupled receptor signaling pathway;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007186//G-protein coupled receptor signaling pathway;GO:0050877//neurological system process;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0050877//neurological system process;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007186//G-protein coupled receptor signaling pathway;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0007165//signal transduction gi|974380264|ref|NP_001305848.1|/1.13704e-178/nociceptin receptor isoform 1x [Mus musculus] 232813 5956 0.01 0.013333333 0.415037499 Up 0.080089511 Shisa7 shisa family member 7 K10583|1|3e-41|174|shr:100927511|ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23] - - - gi|594009839|ref|NP_001277220.1|/0/protein shisa-7 isoform 2 precursor [Mus musculus] 110893 4964 0.03 0.03 3.20E-16 Up 0.080089511 Slc8a3 "solute carrier family 8 (sodium/calcium exchanger), member 3" K05849|1|0.0|1797|mmu:110893|solute carrier family 8 (sodium/calcium exchanger) - - - - 239845 4600 0.03 0.033333333 0.152003093 Up 0.080089511 Gpr156 G protein-coupled receptor 156 K04617|1|0.0|1236|mmu:239845|gamma-aminobutyric acid type B receptor-like GO:0016020//membrane;GO:0045202//synapse GO:0004930//G-protein coupled receptor activity GO:0007165//signal transduction gi|40254201|ref|NP_700443.2|/0/probable G-protein coupled receptor 156 [Mus musculus] 70054 2371 0.043333333 0.04 -0.115477217 Down 0.080089511 Ccdc89 coiled-coil domain containing 89 K12484|1|5e-13|79.3|ola:101164078|Rab11 family-interacting protein 1/2/5;K11498|3|8e-13|78.6|asn:102371243|centromeric protein E;K18626|5|8e-13|78.6|myd:102770051|trichohyalin GO:0043231//intracellular membrane-bounded organelle - - gi|226437669|ref|NP_081574.1|/0/coiled-coil domain-containing protein 89 [Mus musculus] 434203 2846 0.036666667 0.036666667 0 - 0.080089511 Slc28a1 "solute carrier family 28 (sodium-coupled nucleoside transporter), member 1" K11536|1|0.0|1160|mmu:434203|pyrimidine nucleoside transport protein GO:0044459;GO:0016021//integral component of membrane GO:0036094//small molecule binding;GO:0005337//nucleoside transmembrane transporter activity;GO:0005345//purine nucleobase transmembrane transporter activity GO:0006725//cellular aromatic compound metabolic process;GO:0015851//nucleobase transport;GO:0055085//transmembrane transport;GO:0015931//nucleobase-containing compound transport gi|227908843|ref|NP_001004184.2|/0/sodium/nucleoside cotransporter 1 [Mus musculus] 100503565 4892 0.286666667 0.29 0.016678741 Up 0.080089511 Gm9926 predicted gene 9926 - - - - gi|148677716|gb|EDL09663.1|/6.56895e-55/mCG147289 [Mus musculus] 100042198 2872 0.023333333 0.02 -0.222392421 Down 0.080089511 Gm3716 predicted gene 3716 - - - - - 16401 9833 0.726666667 0.726666667 0 - 0.080089511 Itga4 integrin alpha 4 K06483|1|0.0|2050|mmu:16401|integrin alpha 4 GO:0009986//cell surface;GO:0005887//integral component of plasma membrane GO:0043169//cation binding;GO:0005515//protein binding GO:0030098//lymphocyte differentiation;GO:0009888//tissue development;GO:0016337//single organismal cell-cell adhesion;GO:0048870//cell motility;GO:0002682//regulation of immune system process;GO:0048771//tissue remodeling;GO:0007166//cell surface receptor signaling pathway;GO:0007599//hemostasis;GO:0031589//cell-substrate adhesion gi|114326554|ref|NP_034706.3|/0/integrin alpha-4 precursor [Mus musculus] 100126242 945 0.436666667 0.44 0.010971118 Up 0.080089511 Frs3os "fibroblast growth factor receptor substrate 3, opposite strand" K12461|1|2e-17|92.4|lcm:102354082|fibroblast growth factor receptor substrate 2 - - - - 677156 2642 0.03 0.03 0 - 0.080089511 Cyp4f37 "cytochrome P450, family 4, subfamily f, polypeptide 37" "K00490|1|0.0|973|mmu:70101|cytochrome P450, family 4, subfamily F [EC:1.14.14.1];K17726|3|0.0|900|cge:100773326|leukotriene-B4 20-monooxygenase / phylloquinone omega-hydroxylase [EC:1.14.13.30 1.14.13.194]" GO:0031090//organelle membrane "GO:0046906//tetrapyrrole binding;GO:0043169//cation binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen" GO:0006952//defense response;GO:0006690//icosanoid metabolic process "gi|154147571|ref|NP_001093657.1|/0/cytochrome P450, family 4, subfamily f, polypeptide 37 [Mus musculus]" 241197 3314 0.046666667 0.046666667 0 - 0.080089511 Serpinb10 "serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10" K13963|1|0.0|694|rno:266775|serpin B - - - gi|68566084|sp|Q8K1K6.1|SPB10_MOUSE/0/RecName: Full=Serpin B10 22283 15891 0.01 0.01 0 - 0.080089511 Ush2a Usher syndrome 2A K19636|1|0.0|1.053e+04|mmu:22283|usherin GO:0043232;GO:0031528//microvillus membrane;GO:0005578//proteinaceous extracellular matrix;GO:0002141//stereocilia ankle link GO:0008092//cytoskeletal protein binding GO:0045596//negative regulation of cell differentiation;GO:0050954//sensory perception of mechanical stimulus;GO:0009913//epidermal cell differentiation;GO:0042490//mechanoreceptor differentiation;GO:0007601//visual perception gi|145699097|ref|NP_067383.3|/0/usherin precursor [Mus musculus] 77058 1725 0.063333333 0.063333333 0 - 0.080089511 Ccdc183 coiled-coil domain containing 183 - - - - gi|254675160|ref|NP_084135.1|/0/coiled-coil domain-containing protein 183 [Mus musculus] 114871 1979 0.04 0.04 0 - 0.080089511 Psg28 pregnancy-specific glycoprotein 28 K06499|1|6e-120|434|rno:24926|carcinoembryonic antigen-related cell adhesion molecule - GO:0005515//protein binding GO:0001525//angiogenesis;GO:0044703;GO:0038044;GO:0002376//immune system process;GO:0010467//gene expression;GO:0009690//cytokinin metabolic process;GO:0032653 "gi|148691133|gb|EDL23080.1|/0/mCG146231, partial [Mus musculus]" 381798 3395 0.02 0.02 0 - 0.080089511 4930590J08Rik RIKEN cDNA 4930590J08 gene - GO:0031224//intrinsic component of membrane - - gi|38348570|ref|NP_941070.1|/0/uncharacterized protein C3orf20 homolog [Mus musculus] 320429 10553 0.01 0.01 0 - 0.080089511 Trank1 tetratricopeptide repeat and ankyrin repeat containing 1 - - - - gi|257467634|ref|NP_001158131.1|/0/TPR and ankyrin repeat-containing protein 1 [Mus musculus] 56707 7013.64 0.506666667 0.506666667 -3.20E-16 Down 0.080089511 Zfp111 zinc finger protein 111 K09228|1|0.0|1464|mmu:56707|KRAB domain-containing zinc finger protein - - - - 76710 1027 0.15 0.146666667 -0.032421478 Down 0.080089511 2210406O10Rik RIKEN cDNA 2210406O10 gene - - - - gi|12843270|dbj|BAB25920.1|/6.28263e-44/unnamed protein product [Mus musculus] 269629 2933 0.023333333 0.023333333 0 - 0.080089511 Lhfpl3 lipoma HMGIC fusion partner-like 3 - GO:0031224//intrinsic component of membrane;GO:0044459 - GO:0002093//auditory receptor cell morphogenesis gi|225007634|ref|NP_084266.1|/6.66598e-113/lipoma HMGIC fusion partner-like 3 protein isoform 1 [Mus musculus] 52705 4990 5.693333333 5.696666667 0.000844422 Up 0.080089511 Krr1 "KRR1, small subunit (SSU) processome component, homolog (yeast)" K06961|1|1e-164|583|mmu:52705|ribosomal RNA assembly protein GO:0032991//macromolecular complex;GO:0031981//nuclear lumen GO:0003676//nucleic acid binding GO:0042254//ribosome biogenesis gi|74147291|dbj|BAE27537.1|/2.18884e-177/unnamed protein product [Mus musculus] 329780 3451 0.02 0.02 0 - 0.080089511 9330178D15Rik RIKEN cDNA 9330178D15 gene - - - - "gi|148679927|gb|EDL11874.1|/1.48437e-50/mCG144625, partial [Mus musculus]" 68528 975 0.11 0.11 0 - 0.080089511 Smim6 small integral membrane protein 6 - - - - gi|244790378|ref|NP_001156470.1|/2.65638e-09/small integral membrane protein 6 [Mus musculus] 72125 2340 0.026666667 0.026666667 0 - 0.080089511 Amer2 APC membrane recruitment 2 K19407|1|7e-42|175|cmk:103178660|APC membrane recruitment protein 1 - - - gi|257900443|ref|NP_001158177.1|/0/APC membrane recruitment protein 2 isoform 2 [Mus musculus] 432940 1491 13.89 13.89333333 0.000346178 Up 0.080089511 Otulin OTU deubiquitinase with linear linkage specificity K18343|1|0.0|658|mmu:432940|ubiquitin thioesterase otulin [EC:3.4.19.12] - - - - 22097 4306 0.116666667 0.12 0.040641984 Up 0.080089511 Tsix "X (inactive)-specific transcript, opposite strand" - - - - "gi|148682157|gb|EDL14104.1|/1.08296e-37/mCG59677, partial [Mus musculus]" 329727 4997 0.526666667 0.53 0.009102207 Up 0.080089511 Dennd2c DENN/MADD domain containing 2C K20161|1|0.0|1840|mmu:329727|DENN domain-containing protein 2 - GO:0005088//Ras guanyl-nucleotide exchange factor activity - gi|238814338|ref|NP_808525.2|/0/DENN domain-containing protein 2C [Mus musculus] 60367 5422 0.186666667 0.183333333 -0.025995209 Down 0.080089511 Il1rapl2 interleukin 1 receptor accessory protein-like 2 K05170|1|0.0|1312|mmu:60367|interleukin 1 receptor accessory protein-like - - - - 18191 6529 0.01 0.013333333 0.415037499 Up 0.080089511 Nrxn3 neurexin III K07377|1|0.0|950|hgl:101698786|neurexin - - - gi|355390244|ref|NP_001185516.2|/0/neurexin 3 isoform 1 precursor [Mus musculus] 225256 5952 0.013333333 0.016666667 0.321928095 Up 0.080089511 Dsg1b desmoglein 1 beta K07596|1|0.0|1881|mmu:225256|desmoglein 1 - - - - 104079 2093 0.163333333 0.166666667 0.029146346 Up 0.080089511 Nxph3 neurexophilin 3 K16658|1|1e-166|540|ptr:104002950|neurexophilin-3 - GO:0005515//protein binding GO:0007186//G-protein coupled receptor signaling pathway gi|694968847|ref|XP_009431218.1|/8.7258e-166/PREDICTED: neurexophilin-3 [Pan troglodytes] 83454 2319 0.026666667 0.023333333 -0.192645078 Down 0.080089511 Nxf2 nuclear RNA export factor 2 K14284|1|0.0|1338|mmu:83454|nuclear RNA export factor GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle GO:0003723//RNA binding;GO:0003723//RNA binding;GO:0003723//RNA binding GO:0006406//mRNA export from nucleus;GO:0006406//mRNA export from nucleus;GO:0006406//mRNA export from nucleus gi|576080539|ref|NP_001276664.1|/0/nuclear RNA export factor 5 isoform 1 [Mus musculus] 245827 14423 0.016666667 0.02 0.263034406 Up 0.080089511 Fat2 FAT atypical cadherin 2 K16506|1|0.0|8564|mmu:245827|protocadherin Fat 1/2/3 - - - - 232156 5141 0.01 0.013333333 0.415037499 Up 0.080089511 Slc4a5 "solute carrier family 4, sodium bicarbonate cotransporter, member 5" "K13857|1|0.0|1859|mmu:232156|solute carrier family 4 (sodium bicarbonate cotransporter), member 5" GO:0044459;GO:0031224//intrinsic component of membrane GO:0015081//sodium ion transmembrane transporter activity;GO:0015301//anion:anion antiporter activity GO:0044763;GO:0055067;GO:0015711//organic anion transport;GO:0030001//metal ion transport gi|568941538|ref|XP_006506030.1|/0/PREDICTED: electrogenic sodium bicarbonate cotransporter 4 isoform X5 [Mus musculus] 18260 3192 0.17 0.166666667 -0.028569152 Down 0.080089511 Ocln occludin K06088|1|0.0|990|mmu:18260|occludin GO:0043296//apical junction complex;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0044444//cytoplasmic part GO:0005488//binding;GO:0008172//S-methyltransferase activity GO:0012501//programmed cell death;GO:0022411;GO:0006790//sulfur compound metabolic process;GO:0034330;GO:0065003 "gi|148668486|gb|EDL00805.1|/0/occludin, isoform CRA_b, partial [Mus musculus]" 246700 414 0.13 0.133333333 0.036525876 Up 0.080089511 Defb19 defensin beta 19 - - - GO:0006952//defense response "gi|148674027|gb|EDL05974.1|/1.24999e-45/defensin beta 19, partial [Mus musculus]" 21897 2721 0.376666667 0.373333333 -0.01282404 Down 0.080089511 Tlr1 toll-like receptor 1 K05398|1|0.0|1525|mmu:21897|toll-like receptor 1 GO:0030139//endocytic vesicle;GO:0031224//intrinsic component of membrane;GO:0043235//receptor complex;GO:0030139//endocytic vesicle;GO:0031224//intrinsic component of membrane;GO:0043235//receptor complex GO:0071723//lipopeptide binding;GO:0038023//signaling receptor activity;GO:0046983//protein dimerization activity;GO:0071723//lipopeptide binding;GO:0038023//signaling receptor activity;GO:0046983//protein dimerization activity GO:0002274;GO:0071221//cellular response to bacterial lipopeptide;GO:0032147//activation of protein kinase activity;GO:0007154//cell communication;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0006952//defense response;GO:0070340;GO:0002274;GO:0071221//cellular response to bacterial lipopeptide;GO:0032147//activation of protein kinase activity;GO:0007154//cell communication;GO:0042108//positive regulation of cytokine biosynthetic process;GO:0006952//defense response;GO:0070340 gi|13507603|ref|NP_109607.1|/0/toll-like receptor 1 precursor [Mus musculus] 74222 1689 0.036666667 0.033333333 -0.137503524 Down 0.080089511 14-Sep septin 14 K16941|1|0.0|769|mmu:74222|septin 14 GO:0032156//septin cytoskeleton GO:0032550 GO:0044763 gi|160333377|ref|NP_083102.1|/0/septin-14 [Mus musculus] 22635 16481 0.01 0.01 0 - 0.080089511 Zan zonadhesin K18273|1|2e-169|601|ola:101166341|alpha-tectorin GO:0031224//intrinsic component of membrane GO:0005488//binding GO:0022610;GO:0007339//binding of sperm to zona pellucida gi|256665241|ref|NP_035871.2|/0/zonadhesin precursor [Mus musculus] 14918 3633 0.02 0.02 0 - 0.080089511 Gucy2d guanylate cyclase 2d K12321|1|0.0|2109|mmu:14918|guanylate cyclase 2D/E [EC:4.6.1.2] - - - - 68591 2884 2.643333333 2.64 -0.001820436 Down 0.080089511 Mocos molybdenum cofactor sulfurase K15631|1|0.0|1759|mmu:68591|molybdenum cofactor sulfurtransferase [EC:2.8.1.9] - GO:0046914//transition metal ion binding;GO:0043168//anion binding;GO:0003824//catalytic activity GO:0009108//coenzyme biosynthetic process gi|110625679|ref|NP_081055.1|/0/molybdenum cofactor sulfurase [Mus musculus] 76131 2502 0.083333333 0.08 -0.058893689 Down 0.080089511 Depdc1a DEP domain containing 1a - GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0008047//enzyme activator activity;GO:0005488//binding;GO:0008047//enzyme activator activity;GO:0005488//binding;GO:0008047//enzyme activator activity;GO:0005488//binding "GO:0007165//signal transduction;GO:0006351//transcription, DNA-templated;GO:0007165//signal transduction;GO:0006351//transcription, DNA-templated;GO:0007165//signal transduction;GO:0006351//transcription, DNA-templated" gi|285401940|ref|NP_001165564.1|/0/DEP domain-containing protein 1A isoform 3 [Mus musculus] 14106 1366 0.11 0.11 0 - 0.080089511 Foxh1 forkhead box H1 K09400|1|0.0|772|mmu:14106|forkhead box protein H GO:0005667//transcription factor complex "GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0035258//steroid hormone receptor binding;GO:0000975//regulatory region DNA binding;GO:0046332//SMAD binding" GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0003128//heart field specification;GO:0006366//transcription from RNA polymerase II promoter;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0007498//mesoderm development;GO:0030521//androgen receptor signaling pathway;GO:0009855//determination of bilateral symmetry;GO:0035904//aorta development;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0003143//embryonic heart tube morphogenesis;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0009952//anterior/posterior pattern specification gi|6679845|ref|NP_032015.1|/0/forkhead box protein H1 [Mus musculus] 225579 2598 0.043333333 0.04 -0.115477217 Down 0.080089511 Slc27a6 "solute carrier family 27 (fatty acid transporter), member 6" "K08749|1|0.0|1247|mmu:225579|solute carrier family 27 (fatty acid transporter), member 6" - GO:0015645//fatty acid ligase activity - "gi|148677904|gb|EDL09851.1|/0/mCG12542, partial [Mus musculus]" 207607 4979 0.016666667 0.013333333 -0.321928095 Down 0.080089511 Ccdc40 coiled-coil domain containing 40 K20478|1|1e-27|129|dre:557772|golgin subfamily B member 1 GO:0043231//intracellular membrane-bounded organelle - GO:0030323//respiratory tube development;GO:0001889//liver development;GO:0043623//cellular protein complex assembly;GO:0001539//cilium or flagellum-dependent cell motility;GO:0007368//determination of left/right symmetry;GO:0003352//regulation of cilium movement;GO:0003351//epithelial cilium movement "gi|148702741|gb|EDL34688.1|/0/coiled-coil domain containing 40, isoform CRA_a [Mus musculus]" 18789 4518 14.97666667 14.98 0.000321063 Up 0.080089511 Papola poly (A) polymerase alpha K14376|1|0.0|1255|mmu:18789|poly(A) polymerase [EC:2.7.7.19] - - - gi|21914853|ref|NP_035242.1|/0/poly(A) polymerase alpha [Mus musculus] 240873 2064 0.05 0.053333333 0.093109404 Up 0.080089511 Tnfsf18 "tumor necrosis factor (ligand) superfamily, member 18" K05479|1|4e-84|315|mmu:240873|tumor necrosis factor ligand superfamily member 18 - - - - 319955 8422 0.62 0.616666667 -0.007777351 Down 0.080089511 Ercc6 "excision repair cross-complementing rodent repair deficiency, complementation group 6" K10841|1|0.0|2755|mmu:319955|DNA excision repair protein ERCC-6 GO:0031981//nuclear lumen;GO:0043234//protein complex "GO:0032550;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0004386//helicase activity;GO:0042623//ATPase activity, coupled" "GO:0000186//activation of MAPKK activity;GO:0000302//response to reactive oxygen species;GO:0009411//response to UV;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0006289//nucleotide-excision repair;GO:0007601//visual perception;GO:0010212//response to ionizing radiation;GO:0000187//activation of MAPK activity" gi|124487019|ref|NP_001074690.1|/0/DNA excision repair protein ERCC-6 [Mus musculus] 56863 1443 0.04 0.04 0 - 0.080089511 Cldn9 claudin 9 K06087|1|2e-80|302|cge:100769504|claudin GO:0043296//apical junction complex;GO:0016020//membrane GO:0005515//protein binding GO:0016337//single organismal cell-cell adhesion;GO:0007043//cell-cell junction assembly gi|58865348|ref|NP_001011889.1|/1.51934e-79/claudin-9 [Rattus norvegicus] 72022 2568 0.026666667 0.026666667 0 - 0.080089511 Slc35f2 "solute carrier family 35, member F2" "K15287|1|0.0|674|mmu:72022|solute carrier family 35, member F1/2" - - - gi|160333206|ref|NP_082336.3|/0/solute carrier family 35 member F2 [Mus musculus] 414128 1795 0.356666667 0.356666667 0 - 0.080089511 G630064G18Rik RIKEN cDNA G630064G18 gene - - - - gi|148703535|gb|EDL35482.1|/1.25246e-28/mCG148209 [Mus musculus] 320019 2994 0.023333333 0.023333333 0 - 0.080089511 Ptgs2os "prostaglandin-endoperoxide synthase 2, opposite strand" - - - - - 67077 781 0.133333333 0.13 -0.036525876 Down 0.080089511 Tex40 testis expressed 40 K04915|1|4e-24|114|pale:102898989|potassium channel subfamily K member 4 GO:0031224//intrinsic component of membrane GO:0005261//cation channel activity GO:0034220//ion transmembrane transport;GO:0048232//male gamete generation;GO:0030001//metal ion transport;GO:0048869//cellular developmental process gi|95772156|ref|NP_001034583.1|/4.53965e-90/testis-expressed sequence 40 protein [Mus musculus] 12217 15953 0.333333333 0.333333333 0 - 0.080089511 Bsn bassoon K16882|1|8e-153|546|lcm:102355172|protein piccolo GO:0005856//cytoskeleton;GO:0043005//neuron projection;GO:0044456;GO:0031981//nuclear lumen GO:0043169//cation binding GO:0006996//organelle organization "gi|148689323|gb|EDL21270.1|/0/bassoon, partial [Mus musculus]" 103712 1626 0.036666667 0.036666667 0 - 0.080089511 6330403K07Rik RIKEN cDNA 6330403K07 gene "K12798|1|2e-07|60.1|bacu:102999016|NACHT, LRR and PYD domains-containing protein 1" - - - gi|40548844|gb|AAR87485.1|/1.93645e-33/UGS148 protein [Mus musculus] 67573 5444.31 0.25 0.253333333 0.019108823 Up 0.080089511 Loxl4 lysyl oxidase-like 4 K00280|1|0.0|1498|mmu:67573|lysyl oxidase-like protein 2/3/4 [EC:1.4.3.-] - - - gi|569007721|ref|XP_006527361.1|/0/PREDICTED: lysyl oxidase homolog 4 isoform X2 [Mus musculus] 56471 1328 0.113333333 0.113333333 0 - 0.080089511 Stmn4 stathmin-like 4 K04381|1|3e-49|198|gja:107110808|stathmin GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle - GO:0031109//microtubule polymerization or depolymerization;GO:0031109//microtubule polymerization or depolymerization;GO:0031109//microtubule polymerization or depolymerization "gi|148704048|gb|EDL35995.1|/1.34529e-103/stathmin-like 4, isoform CRA_c, partial [Mus musculus]" 622976 2801 0.023333333 0.023333333 0 - 0.080089511 Gm6377 predicted gene 6377 - - - - gi|85702300|ref|NP_001033006.1|/1.20892e-172/uncharacterized protein LOC622976 [Mus musculus] 269116 9406 0.013333333 0.013333333 0 - 0.080089511 Nfasc neurofascin K06757|1|0.0|2250|cge:100752815|neurofascin - - - gi|755494365|ref|XP_011246320.1|/0/PREDICTED: neurofascin isoform X14 [Mus musculus] 26913 4267 0.05 0.053333333 0.093109404 Up 0.080089511 Gprin1 G protein-regulated inducer of neurite outgrowth 1 K11657|1|9e-11|72.8|obi:106877384|remodeling and spacing factor 1;K10955|3|6e-10|70.1|aam:106496918|intestinal mucin-2 - - - - 229933 3921 0.02 0.02 0 - 0.080089511 Clca2 chloride channel accessory 2 K05028|1|0.0|1821|mmu:229933|calcium-activated chloride channel regulator 2 GO:0031224//intrinsic component of membrane GO:0005253//anion channel activity GO:0015698//inorganic anion transport;GO:0022610 gi|30520101|ref|NP_848812.1|/0/calcium-activated chloride channel regulator 2 precursor [Mus musculus] 244882 2225 0.05 0.05 0 - 0.080089511 Tnfaip8l3 "tumor necrosis factor, alpha-induced protein 8-like 3" - - - - gi|880879841|ref|XP_005069605.2|/6.05993e-116/PREDICTED: LOW QUALITY PROTEIN: tumor necrosis factor alpha-induced protein 8-like protein 3 [Mesocricetus auratus] 214593 4554 0.03 0.03 3.20E-16 Up 0.080089511 Duox2 dual oxidase 2 K13411|1|0.0|2962|mmu:214593|dual oxidase [EC:1.6.3.1 1.11.1.-] - - - - 381107 2591 0.026666667 0.026666667 0 - 0.080089511 Tmem232 transmembrane protein 232 - GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - - gi|113374162|ref|NP_001008973.2|/0/transmembrane protein 232 isoform a [Mus musculus] 108151 6521 0.073333333 0.073333333 0 - 0.080089511 Sema3d "sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D" K06840|1|0.0|1576|mmu:108151|semaphorin 3 - - GO:0048731//system development;GO:0048869//cellular developmental process "gi|148706749|gb|EDL38696.1|/0/sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D, isoform CRA_c, partial [Mus musculus]" 192734 4601 0.15 0.146666667 -0.032421478 Down 0.080089511 Lrrc75b leucine rich repeat containing 75B - - - - "gi|148699963|gb|EDL31910.1|/1.75267e-118/expressed sequence AI646023, isoform CRA_a, partial [Mus musculus]" 235472 8764 0.016666667 0.013333333 -0.321928095 Down 0.080089511 Prtg protogenin K06765|1|2e-80|305|mze:101477310|deleted in colorectal carcinoma;K06766|3|1e-79|302|dre:266983|neogenin - - - - 237858 3237 4.006666667 4.006666667 0 - 0.080089511 Tusc5 tumor suppressor candidate 5 - GO:0031224//intrinsic component of membrane - GO:0050896//response to stimulus "gi|148680918|gb|EDL12865.1|/3.07176e-66/tumor suppressor candidate 5, partial [Mus musculus]" 545551 2228 0.046666667 0.043333333 -0.106915204 Down 0.080089511 BC021767 cingulin pseudogene K06102|1|3e-132|474|mmu:70737|cingulin - - - - 24060 2039 3.31 3.31 0 - 0.080089511 Slc35a1 "solute carrier family 35 (CMP-sialic acid transporter), member 1" "K15272|1|0.0|647|mmu:24060|solute carrier family 35 (UDP-sugar transporter), member A1/2/3" GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane GO:0015215//nucleotide transmembrane transporter activity;GO:0005402//cation:sugar symporter activity GO:0006862//nucleotide transport gi|225543514|ref|NP_036025.2|/0/CMP-sialic acid transporter [Mus musculus] 64176 5341 0.11 0.113333333 0.043068722 Up 0.080089511 Sv2b synaptic vesicle glycoprotein 2 b "K06258|1|0.0|1342|mmu:64176|MFS transporter, VNT family, synaptic vesicle glycoprotein 2" GO:0008021//synaptic vesicle;GO:0031224//intrinsic component of membrane;GO:0030141//secretory granule;GO:0008021//synaptic vesicle;GO:0031224//intrinsic component of membrane;GO:0030141//secretory granule GO:0005215//transporter activity;GO:0005215//transporter activity GO:0044765//single-organism transport;GO:0007267//cell-cell signaling;GO:0044765//single-organism transport;GO:0007267//cell-cell signaling gi|533133321|ref|XP_005381650.1|/0/PREDICTED: synaptic vesicle glycoprotein 2B [Chinchilla lanigera] 212892 3650 0.03 0.03 0 - 0.080089511 Rsph4a radial spoke head 4 homolog A (Chlamydomonas) K19756|1|0.0|1202|mmu:212892|radial spoke head protein 4A GO:0043232;GO:0043231//intracellular membrane-bounded organelle - - gi|242397427|ref|NP_001156429.1|/0/radial spoke head protein 4 homolog A [Mus musculus] 67381 1304 15.43 15.42666667 -0.000311698 Down 0.080089511 Med4 mediator complex subunit 4 K15146|1|2e-124|448|mmu:67381|mediator of RNA polymerase II transcription subunit 4 GO:0043234//protein complex;GO:0031981//nuclear lumen "GO:0008134//transcription factor binding;GO:0003713//transcription coactivator activity;GO:0001076//transcription factor activity, RNA polymerase II transcription factor binding" GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter gi|74216864|dbj|BAE26554.1|/1.21675e-125/unnamed protein product [Mus musculus] 210940 4331 0.016666667 0.016666667 0 - 0.080089511 4931408C20Rik RIKEN cDNA 4931408C20 gene - - - - gi|237757316|ref|NP_001028936.2|/0/uncharacterized protein LOC210940 [Mus musculus] 240816 3640 0.02 0.02 0 - 0.080089511 Rgsl1 regulator of G-protein signaling like 1 - - - - gi|568909041|ref|XP_006529637.1|/0/PREDICTED: regulator of G-protein signaling protein-like isoform X1 [Mus musculus] 12823 10542 0.01 0.01 0 - 0.080089511 Col19a1 "collagen, type XIX, alpha 1" "K16630|1|5e-45|187|lcm:102347006|collagen, type XXII, alpha" - - GO:0043062//extracellular structure organization;GO:0014706//striated muscle tissue development gi|568905676|ref|XP_006495706.1|/0/PREDICTED: collagen alpha-1(XIX) chain isoform X3 [Mus musculus] 21925 705 0.146666667 0.143333333 -0.033166864 Down 0.080089511 Tnnc2 "troponin C2, fast" "K12042|1|4e-74|279|mmu:21925|troponin C, skeletal muscle" GO:0005865//striated muscle thin filament GO:0046872//metal ion binding;GO:0008092//cytoskeletal protein binding GO:0006941//striated muscle contraction "gi|955517176|ref|XP_014642906.1|/2.42707e-73/PREDICTED: troponin C, skeletal muscle isoform X1 [Ceratotherium simum simum]" 100502868 5487 0.076666667 0.08 0.061400545 Up 0.080089511 Gm20597 "predicted gene, 20597" - - - - "gi|148673140|gb|EDL05087.1|/3.11465e-61/mCG145022, partial [Mus musculus]" 19283 8068 0.04 0.04 0 - 0.080089511 Ptprz1 "protein tyrosine phosphatase, receptor type Z, polypeptide 1" K08114|1|0.0|4061|rno:25613|receptor-type tyrosine-protein phosphatase zeta [EC:3.1.3.48] - - - gi|901694078|ref|NP_001297993.1|/0/receptor-type tyrosine-protein phosphatase zeta isoform 4 precursor [Mus musculus] 72685 5139 0.033333333 0.03 -0.152003093 Down 0.080089511 Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 K09526|1|0.0|1666|mmu:72685|DnaJ homolog subfamily C member 6 - - - - 382053 1908 0.033333333 0.033333333 0 - 0.080089511 Ces3a carboxylesterase 3A K15743|1|0.0|1040|mmu:382053|carboxylesterase 3/5 [EC:3.1.1.1] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0052689//carboxylic ester hydrolase activity;GO:0052689//carboxylic ester hydrolase activity - gi|257743054|ref|NP_001158153.1|/0/carboxylesterase 3A isoform 2 precursor [Mus musculus] 20753 807 0.13 0.126666667 -0.037474705 Down 0.080089511 Sprr1a small proline-rich protein 1A K15601|1|2e-17|91.7|bfo:BRAFLDRAFT_124949|lysine-specific demethylase 3 [EC:1.14.11.-] GO:0044424 GO:0005515//protein binding;GO:0005198//structural molecule activity GO:0030216//keratinocyte differentiation;GO:0006464//cellular protein modification process gi|6678115|ref|NP_033290.1|/9.33963e-65/cornifin-A [Mus musculus] 434285 1764 0.033333333 0.033333333 0 - 0.080089511 BB014433 expressed sequence BB014433 K03345|1|1e-29|133|mdo:103099737|sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68];K03006|3|6e-28|128|api:100166173|DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6];K16522|4|3e-26|122|ngi:103749266|A-kinase anchor protein 5 - - - gi|223459972|gb|AAI39041.1|/0/Expressed sequence BB014433 [Mus musculus] 14302 4669 0.2 0.196666667 -0.024247546 Down 0.080089511 Frk fyn-related kinase K08892|1|0.0|1037|mmu:14302|fyn-related kinase [EC:2.7.10.2] GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane GO:0004713//protein tyrosine kinase activity;GO:0032550;GO:0004713//protein tyrosine kinase activity;GO:0032550 GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0048869//cellular developmental process;GO:0006796//phosphate-containing compound metabolic process;GO:0006464//cellular protein modification process;GO:0048869//cellular developmental process "gi|148672946|gb|EDL04893.1|/0/fyn-related kinase, isoform CRA_b, partial [Mus musculus]" 72219 4281 0.016666667 0.016666667 0 - 0.080089511 Spata31d1a "spermatogenesis associated 31 subfamily D, member 1A" K13172|1|3e-06|57.8|ngi:103744014|serine/arginine repetitive matrix protein 2 - - - gi|140970996|ref|NP_082433.2|/0/spermatogenesis-associated protein 31D1 [Mus musculus] 100043224 914 0.013333333 0.01 -0.415037499 Down 0.080089511 Gm4301 predicted gene 4301 K12881|1|1e-103|378|mmu:100043292|THO complex subunit 4 GO:0043234//protein complex;GO:0005681//spliceosomal complex GO:0043566//structure-specific DNA binding GO:0006406//mRNA export from nucleus gi|262263336|ref|NP_001160109.1|/3.5709e-114/uncharacterized protein LOC100043224 [Mus musculus] 260315 7782 0.136666667 0.136666667 0 - 0.080089511 Nav3 neuron navigator 3 K19483|1|0.0|2089|ola:101159237|neuron navigator 2 [EC:3.6.4.12] - - - gi|124486648|ref|NP_001074504.1|/0/neuron navigator 3 [Mus musculus] 100043686 3723 0.04 0.036666667 -0.125530882 Down 0.080089511 Amy2a3 amylase 2a3 K01176|1|0.0|1090|mmu:100043688|alpha-amylase [EC:3.2.1.1] GO:0044421 GO:0046872//metal ion binding;GO:0043168//anion binding;GO:0016160//amylase activity GO:0005975//carbohydrate metabolic process "gi|148680466|gb|EDL12413.1|/0/mCG11265, isoform CRA_a, partial [Mus musculus]" 66116 1027 1.086666667 1.09 0.004418671 Up 0.080089511 Nat8f1 N-acetyltransferase 8 (GCN5-related) family member 1 K18309|1|3e-24|115|dre:564754|aspartate N-acetyltransferase [EC:2.3.1.17];K20180|4|2e-22|108|mgp:100538837|vacuolar protein sorting-associated protein 16 GO:0019866//organelle inner membrane;GO:0031224//intrinsic component of membrane GO:0016407//acetyltransferase activity GO:0048598//embryonic morphogenesis gi|227498710|ref|NP_075649.2|/4.49939e-111/probable N-acetyltransferase CML1 [Mus musculus] 320111 3277 0.023333333 0.02 -0.222392421 Down 0.080089511 Prr18 proline rich 18 - - - - gi|255308901|ref|NP_848889.3|/1.34929e-128/proline-rich protein 18 [Mus musculus] 27412 2640 0.186666667 0.183333333 -0.025995209 Down 0.080089511 Peg12 paternally expressed 12 K03069|1|2e-96|356|mmu:27412|frequently rearranged in advanced T-cell lymphomas 1 GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding GO:0007166//cell surface receptor signaling pathway;GO:0006886//intracellular protein transport gi|7305067|ref|NP_038816.1|/1.90628e-95/paternally expressed 12 [Mus musculus] 71461 4255 1.13 1.133333333 0.004249473 Up 0.080089511 Ptk7 PTK7 protein tyrosine kinase 7 K05127|1|0.0|2122|mmu:71461|PTK7 protein tyrosine kinase 7 [EC:2.7.10.1] GO:0031224//intrinsic component of membrane;GO:0030054//cell junction GO:0032550;GO:0004713//protein tyrosine kinase activity "GO:0030324//lung development;GO:0009611//response to wounding;GO:0014020;GO:0060560//developmental growth involved in morphogenesis;GO:0032526//response to retinoic acid;GO:0010975//regulation of neuron projection development;GO:0048870//cell motility;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0030036//actin cytoskeleton organization;GO:0022610;GO:0006464//cellular protein modification process;GO:0030859//polarized epithelial cell differentiation" "gi|148691564|gb|EDL23511.1|/0/PTK7 protein tyrosine kinase 7, isoform CRA_a, partial [Mus musculus]" 11775 3816 0.02 0.016666667 -0.263034406 Down 0.080089511 Ap3b2 "adaptor-related protein complex 3, beta 2 subunit" K12397|1|0.0|1320|mmu:11775|AP-3 complex subunit beta GO:0031981//nuclear lumen;GO:0030119//AP-type membrane coat adaptor complex;GO:0031982//vesicle - GO:0008088//axo-dendritic transport;GO:0048489//synaptic vesicle transport;GO:0015031//protein transport gi|74144160|dbj|BAE22164.1|/0/unnamed protein product [Mus musculus] 18020 3388 1.353333333 1.353333333 0 - 0.080089511 Nfatc2ip "nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein" - GO:0043231//intracellular membrane-bounded organelle GO:0005488//binding "GO:0006351//transcription, DNA-templated;GO:0044707" gi|12838793|dbj|BAB24331.1|/9.57325e-171/unnamed protein product [Mus musculus] 240332 3362 0.023333333 0.02 -0.222392421 Down 0.080089511 Slc6a7 "solute carrier family 6 (neurotransmitter transporter, L-proline), member 7" "K05038|1|0.0|1172|mmu:240332|solute carrier family 6 (neurotransmitter transporter, amino acid) member 5/7/9/14" GO:0031224//intrinsic component of membrane GO:0008324//cation transmembrane transporter activity;GO:0015291//secondary active transmembrane transporter activity;GO:0005326//neurotransmitter transporter activity GO:0003333//amino acid transmembrane transport;GO:0006812//cation transport "gi|148677845|gb|EDL09792.1|/0/solute carrier family 6 (neurotransmitter transporter, L-proline), member 7, isoform CRA_b, partial [Mus musculus]" 18505 3376 0.063333333 0.06 -0.078002512 Down 0.080089511 Pax3 paired box 3 K09381|1|0.0|935|mmu:18505|paired box protein 3/7 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex;GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex "GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0000981//RNA polymerase II transcription factor activity, sequence-specific DNA binding;GO:0019904//protein domain specific binding;GO:0003677//DNA binding" GO:0014020;GO:0010092//specification of organ identity;GO:0006366//transcription from RNA polymerase II promoter;GO:0012501//programmed cell death;GO:0001667//ameboidal-type cell migration;GO:0008283//cell proliferation;GO:0050954//sensory perception of mechanical stimulus;GO:0021515//cell differentiation in spinal cord;GO:0030182//neuron differentiation;GO:0014020;GO:0010092//specification of organ identity;GO:0006366//transcription from RNA polymerase II promoter;GO:0012501//programmed cell death;GO:0001667//ameboidal-type cell migration;GO:0008283//cell proliferation;GO:0050954//sensory perception of mechanical stimulus;GO:0021515//cell differentiation in spinal cord;GO:0030182//neuron differentiation gi|226958472|ref|NP_032807.3|/0/paired box protein Pax-3 isoform a [Mus musculus] 23985 3083 0.023333333 0.023333333 0 - 0.080089511 Slc26a4 "solute carrier family 26, member 4" "K14702|1|0.0|1294|mmu:23985|solute carrier family 26 (sodium-independent chloride/iodide transporter), member 4" GO:0044459;GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity GO:0015698//inorganic anion transport;GO:0008104//protein localization;GO:0044763;GO:0055067;GO:0009653//anatomical structure morphogenesis "gi|148704964|gb|EDL36911.1|/0/solute carrier family 26, member 4, partial [Mus musculus]" 12653 2733 0.073333333 0.07 -0.067114196 Down 0.080089511 Chgb chromogranin B K19991|1|0.0|1033|mmu:12653|chromogranin-B "GO:0016023//cytoplasmic, membrane-bounded vesicle" - - gi|6680934|ref|NP_031720.1|/0/secretogranin-1 precursor [Mus musculus] 170812 494 0.11 0.11 0 - 0.080089511 Ahsp alpha hemoglobin stabilizing protein - - GO:0005515//protein binding GO:0030099//myeloid cell differentiation;GO:0044267//cellular protein metabolic process;GO:0031647//regulation of protein stability gi|18875418|ref|NP_573508.1|/5.4094e-52/alpha-hemoglobin-stabilizing protein [Mus musculus] 78420 658 0.16 0.156666667 -0.030373649 Down 0.080089511 Bcas3os2 breast carcinoma amplified sequence 3 opposite strand 2 - - - - - 619327 3502 0.02 0.02 0 - 0.080089511 G630093K05Rik RIKEN cDNA G630093K05 gene - - - - gi|74196599|dbj|BAE34410.1|/1.36494e-19/unnamed protein product [Mus musculus] 11906 16439 1.086666667 1.083333333 -0.004432246 Down 0.080089511 Zfhx3 zinc finger homeobox 3 K09378|1|0.0|5228|mmu:11906|AT-binding transcription factor 1 GO:0043231//intracellular membrane-bounded organelle;GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0005515//protein binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000975//regulatory region DNA binding "GO:0006351//transcription, DNA-templated;GO:0045445//myoblast differentiation;GO:0048513//animal organ development" gi|148679469|gb|EDL11416.1|/0/AT motif binding factor 1 [Mus musculus] 21689 1408 0.04 0.036666667 -0.125530882 Down 0.080089511 Tekt1 tektin 1 K18628|1|0.0|821|mmu:21689|tektin-1 GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton - GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization;GO:0007010//cytoskeleton organization gi|117956379|ref|NP_035699.2|/0/tektin-1 [Mus musculus] 232827 3404 0.02 0.02 0 - 0.080089511 Nlrp2 "NLR family, pyrin domain containing 2" "K19409|1|0.0|2082|mmu:232827|NACHT, LRR and PYD domains-containing protein 2/7" - GO:0019904//protein domain specific binding GO:0006915//apoptotic process;GO:0032731//positive regulation of interleukin-1 beta production "gi|148699347|gb|EDL31294.1|/0/NACHT, leucine rich repeat and PYD containing 2, isoform CRA_b, partial [Mus musculus]" 54371 6256 0.533333333 0.53 -0.00904514 Down 0.080089511 Chst2 carbohydrate sulfotransferase 2 K04745|1|0.0|807|mmu:54371|carbohydrate 6-sulfotransferase 2 [EC:2.8.2.-] GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane GO:0008146//sulfotransferase activity GO:0006952//defense response;GO:0006024//glycosaminoglycan biosynthetic process;GO:0044238//primary metabolic process;GO:0006790//sulfur compound metabolic process;GO:1901071;GO:0032502//developmental process gi|148688988|gb|EDL20935.1|/0/carbohydrate sulfotransferase 2 [Mus musculus] 230678 1879 0.033333333 0.033333333 0 - 0.080089511 Tmem125 transmembrane protein 125 - - - - gi|157952196|ref|NP_001101437.2|/1.25933e-95/transmembrane protein 125 [Rattus norvegicus] 329483 3949 0.03 0.026666667 -0.169925001 Down 0.080089511 Gm14015 predicted gene 14015 - - - - - 628870 6984 0.01 0.013333333 0.415037499 Up 0.080089511 Otogl otogelin-like K03900|1|0.0|646|lcm:102356867|von Willebrand factor - "GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds" GO:0019566//arabinose metabolic process gi|294774587|ref|NP_001171038.1|/0/otogelin-like protein precursor [Mus musculus] 320152 3969 0.076666667 0.08 0.061400545 Up 0.080089511 4930412C18Rik RIKEN cDNA 4930412C18 gene - - - - "gi|148673719|gb|EDL05666.1|/4.71702e-56/mCG145028, partial [Mus musculus]" 27878 2159 3.43 3.433333333 0.001401355 Up 0.080089511 Tada1 transcriptional adaptor 1 K11317|1|8e-177|623|mmu:27878|transcriptional adapter 1 GO:0070461//SAGA-type complex GO:0003712//transcription cofactor activity;GO:0008080//N-acetyltransferase activity "GO:0006351//transcription, DNA-templated;GO:0016573//histone acetylation" gi|21313610|ref|NP_084521.1|/6.55264e-176/transcriptional adapter 1 [Mus musculus] 83555 2128 0.05 0.046666667 -0.099535674 Down 0.080089511 Tex13 testis expressed gene 13 - - - - gi|13878205|ref|NP_113558.1|/9.21488e-90/testis-expressed sequence 13B protein [Mus musculus] 208439 7048 0.123333333 0.126666667 0.038474148 Up 0.080089511 Klhl29 kelch-like 29 K10465|1|0.0|1588|mcf:102145809|kelch-like protein 29 - - - gi|28972876|dbj|BAC65854.1|/0/mKIAA1921 protein [Mus musculus] 170472 4001 2.84 2.84 0 - 0.080089511 Recql5 RecQ protein-like 5 K10902|1|0.0|1908|mmu:170472|ATP-dependent DNA helicase Q5 [EC:3.6.4.12] GO:0044451 GO:0003824//catalytic activity;GO:0032550 GO:0007166//cell surface receptor signaling pathway gi|18485510|ref|NP_569721.1|/0/ATP-dependent DNA helicase Q5 [Mus musculus] 73246 1959 0.033333333 0.03 -0.152003093 Down 0.080089511 Rassf6 Ras association (RalGDS/AF-6) domain family member 6 K09854|1|0.0|642|mmu:73246|Ras association domain-containing protein 6 - - GO:0006915//apoptotic process;GO:0007154//cell communication;GO:0006915//apoptotic process;GO:0007154//cell communication "gi|211830477|gb|AAH39934.2|/0/Rassf6 protein, partial [Mus musculus]" 74337 2449 0.106666667 0.106666667 0 - 0.080089511 Palm3 paralemmin 3 K04573|1|2e-10|70.9|xla:397994|neurofilament medium polypeptide (neurofilament 3);K04572|2|1e-09|68.2|dre:793912|neurofilament light polypeptide;K19607|3|4e-09|66.2|fch:102057669|X-linked retinitis pigmentosa GTPase regulator GO:0044424;GO:0016020//membrane GO:0032550 GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0002237//response to molecule of bacterial origin gi|124430707|ref|NP_083153.1|/0/paralemmin-3 [Mus musculus] 193034 3587 0.046666667 0.05 0.099535674 Up 0.080089511 Trpv1 "transient receptor potential cation channel, subfamily V, member 1" K05222|1|0.0|1654|mmu:193034|transient receptor potential cation channel subfamily V member 1 GO:0009986//cell surface;GO:0031224//intrinsic component of membrane;GO:0032589//neuron projection membrane;GO:0044444//cytoplasmic part;GO:0044297//cell body;GO:0097060//synaptic membrane GO:0004697//protein kinase C activity;GO:0005261//cation channel activity;GO:0032550;GO:0005515//protein binding;GO:0016247//channel regulator activity GO:0033555//multicellular organismal response to stress;GO:0006915//apoptotic process;GO:0048871//multicellular organismal homeostasis;GO:0006809//nitric oxide biosynthetic process;GO:0019233//sensory perception of pain;GO:0002021//response to dietary excess;GO:0009266//response to temperature stimulus;GO:0006953//acute-phase response;GO:0022405//hair cycle process;GO:0044708//single-organism behavior;GO:0001696//gastric acid secretion;GO:0070848//response to growth factor;GO:0042116//macrophage activation;GO:0006464//cellular protein modification process;GO:0006835//dicarboxylic acid transport;GO:0006816//calcium ion transport;GO:0009725//response to hormone;GO:0014832//urinary bladder smooth muscle contraction;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0050951//sensory perception of temperature stimulus;GO:0010721//negative regulation of cell development gi|755537770|ref|XP_006532643.2|/0/PREDICTED: transient receptor potential cation channel subfamily V member 1 isoform X1 [Mus musculus] 241324 6393 0.01 0.013333333 0.415037499 Up 0.080089511 Crb2 crumbs family member 2 K16681|1|0.0|2595|mmu:241324|protein crumbs - - - - 20379 1780 0.036666667 0.033333333 -0.137503524 Down 0.080089511 Sfrp4 secreted frizzled-related protein 4 K02185|1|8e-174|612|mmu:20379|secreted frizzled-related protein 4 GO:0043231//intracellular membrane-bounded organelle;GO:0044421 GO:0005515//protein binding GO:0002090//regulation of receptor internalization;GO:0010467//gene expression;GO:0072506;GO:0008283//cell proliferation;GO:0009913//epidermal cell differentiation;GO:0006915//apoptotic process;GO:0007254//JNK cascade;GO:0030178//negative regulation of Wnt signaling pathway;GO:0044092//negative regulation of molecular function;GO:0044767//single-organism developmental process;GO:0030177//positive regulation of Wnt signaling pathway;GO:0043271//negative regulation of ion transport gi|7710094|ref|NP_057896.1|/6.96412e-173/secreted frizzled-related sequence protein 4 precursor [Mus musculus] 214944 6030 0.19 0.193333333 0.025090981 Up 0.080089511 Mob3b MOB kinase activator 3B K06685|1|3e-80|303|cel:CELE_T12B3.4|MOB kinase activator 1 - "GO:0016772//transferase activity, transferring phosphorus-containing groups;GO:0043169//cation binding" GO:0006796//phosphate-containing compound metabolic process gi|30017359|ref|NP_835162.1|/3.05444e-126/MOB kinase activator 3B [Mus musculus] 233879 518 0.106666667 0.103333333 -0.04580369 Down 0.080089511 Asphd1 aspartate beta-hydroxylase domain containing 1 K00476|1|6e-21|102|tad:TRIADDRAFT_31864|aspartate beta-hydroxylase [EC:1.14.11.16] GO:0031227//intrinsic component of endoplasmic reticulum membrane - - gi|744612662|ref|XP_010994481.1|/4.47442e-77/PREDICTED: aspartate beta-hydroxylase domain-containing protein 1 [Camelus dromedarius] 231830 3346 1.796666667 1.8 0.002674134 Up 0.080089511 Micall2 MICAL-like 2 K19948|1|0.0|1546|mmu:231830|MICAL-like protein GO:0043296//apical junction complex;GO:0015629//actin cytoskeleton GO:0043169//cation binding GO:0016192//vesicle-mediated transport "gi|148687191|gb|EDL19138.1|/0/RIKEN cDNA A930021H16, isoform CRA_a [Mus musculus]" 381651 759 0.073333333 0.07 -0.067114196 Down 0.080089511 Gm1045 predicted gene 1045 - - - - - 228801 1653 0.063333333 0.063333333 0 - 0.080089511 Bpifb1 "BPI fold containing family B, member 1" - GO:0044421;GO:0044421 GO:0005488//binding;GO:0005488//binding - gi|59939910|ref|NP_700467.2|/0/BPI fold-containing family B member 1 isoform 2 precursor [Mus musculus] 269615 5598 0.033333333 0.036666667 0.137503524 Up 0.080089511 Plch2 "phospholipase C, eta 2" "K19006|1|0.0|2649|mmu:269615|phosphatidylinositol phospholipase C, eta [EC:3.1.4.11]" GO:0016020//membrane;GO:0044424 GO:0060089;GO:0046872//metal ion binding;GO:0042578//phosphoric ester hydrolase activity;GO:0008289//lipid binding;GO:0004620//phospholipase activity GO:0007165//signal transduction;GO:0006650//glycerophospholipid metabolic process "gi|164565357|ref|NP_001106831.1|/0/1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 isoform b [Mus musculus]" 245578 8607 0.013333333 0.01 -0.415037499 Down 0.080089511 Pcdh11x protocadherin 11 X-linked K16498|1|0.0|2107|mmu:245578|protocadherin delta 1 - - - - 432615 2311 0.026666667 0.023333333 -0.192645078 Down 0.080089511 Gm11733 predicted gene 11733 - - - - - 106021 3842 2.766666667 2.77 0.001737141 Up 0.080089511 Topors "topoisomerase I binding, arginine/serine-rich" K10631|1|0.0|925|mmu:106021|E3 ubiquitin-protein ligase Topors [EC:2.3.2.27] GO:0031513//nonmotile primary cilium;GO:0016604//nuclear body;GO:0005813//centrosome;GO:0043234//protein complex GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0019787//ubiquitin-like protein transferase activity;GO:0019899//enzyme binding "GO:0000209//protein polyubiquitination;GO:0006351//transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0012501//programmed cell death;GO:0034504//protein localization to nucleus;GO:0031398//positive regulation of protein ubiquitination;GO:0008283//cell proliferation;GO:0006511//ubiquitin-dependent protein catabolic process" gi|74224529|dbj|BAE25253.1|/0/unnamed protein product [Mus musculus] 21646 1434 0.04 0.04 0 - 0.080089511 Tcte2 t-complex-associated testis expressed 2 - - - - gi|114687623|ref|NP_071706.2|/1.28951e-38/t-complex-associated testis expressed 2 [Mus musculus] 353047 5144 7.51 7.513333333 0.000640202 Up 0.080089511 Plekhm1 "pleckstrin homology domain containing, family M (with RUN domain) member 1" K19330|1|4e-36|157|ame:413668|run domain Beclin-1 interacting and cysteine-rich containing protein GO:0044424 GO:0008289//lipid binding;GO:0043169//cation binding GO:0007165//signal transduction gi|33942120|ref|NP_898855.1|/0/pleckstrin homology domain-containing family M member 1 [Mus musculus] 17933 7104 0.013333333 0.013333333 0 - 0.080089511 Myt1l myelin transcription factor 1-like K11307|1|2e-07|62.8|myd:102751848|histone acetyltransferase MYST2 [EC:2.3.1.48] GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0044212//transcription regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0046914//transition metal ion binding;GO:0001071//nucleic acid binding transcription factor activity GO:0048869//cellular developmental process;GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0048869//cellular developmental process;GO:0048731//system development;GO:0006366//transcription from RNA polymerase II promoter gi|148271075|ref|NP_032692.2|/0/myelin transcription factor 1-like protein isoform 2 [Mus musculus] 408064 917 0.726666667 0.73 0.006602735 Up 0.080089511 BC064078 cDNA sequence BC064078 K10072|1|2e-06|55.5|cge:103159028|C-type lectin domain family 2 member D - GO:0005488//binding - "gi|148667493|gb|EDK99909.1|/4.18769e-46/mCG1037163, partial [Mus musculus]" 76634 722 0.076666667 0.073333333 -0.064130337 Down 0.080089511 1700110C19Rik RIKEN cDNA 1700110C19 gene - - - - - 13074 1841 0.033333333 0.033333333 0 - 0.080089511 Cyp17a1 "cytochrome P450, family 17, subfamily a, polypeptide 1" K00512|1|0.0|1023|mmu:13074|steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone aldolase [EC:1.14.14.19 4.1.2.30] GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0044297//cell body GO:0046914//transition metal ion binding;GO:0008395//steroid hydroxylase activity;GO:0046906//tetrapyrrole binding GO:0010893//positive regulation of steroid biosynthetic process;GO:0032496//response to lipopolysaccharide;GO:0046677//response to antibiotic;GO:0046683//response to organophosphorus;GO:0008406//gonad development;GO:0042537//benzene-containing compound metabolic process;GO:0021543//pallium development;GO:0007292//female gamete generation;GO:0009991//response to extracellular stimulus;GO:0009314//response to radiation;GO:0006950//response to stress;GO:0035270//endocrine system development;GO:0032870//cellular response to hormone stimulus "gi|160948601|ref|NP_031835.3|/0/steroid 17-alpha-hydroxylase/17,20 lyase precursor [Mus musculus]" 83603 3071 0.05 0.046666667 -0.099535674 Down 0.080089511 Elovl4 "elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4" K10249|1|3e-180|635|mmu:83603|elongation of very long chain fatty acids protein 4 [EC:2.3.1.199] GO:0031227//intrinsic component of endoplasmic reticulum membrane GO:0003824//catalytic activity GO:0000038//very long-chain fatty acid metabolic process;GO:0030497//fatty acid elongation gi|225543343|ref|NP_683743.2|/2.52688e-179/elongation of very long chain fatty acids protein 4 [Mus musculus] 269633 1805 0.113333333 0.11 -0.043068722 Down 0.080089511 Wdr86 WD repeat domain 86 K10260|1|1e-37|160|amj:102569416|F-box and WD-40 domain protein 7 - - - gi|124517674|ref|NP_001074910.1|/0/WD repeat-containing protein 86 [Mus musculus] 71145 3809 8.683333333 8.683333333 0 - 0.080089511 Scara5 "scavenger receptor class A, member 5" K06558|1|4e-17|93.2|fca:101081290|macrophage scavenger receptor 1 - - - - 432838 1903 0.033333333 0.033333333 0 - 0.080089511 Gm5460 predicted gene 5460 - - - - gi|568988087|ref|XP_006519274.1|/1.16302e-72/PREDICTED: uncharacterized protein LOC432838 isoform X4 [Mus musculus] 67642 1257 0.12 0.12 0 - 0.080089511 4930515G01Rik RIKEN cDNA 4930515G01 gene - - - - gi|26334645|dbj|BAC31023.1|/3.75795e-68/unnamed protein product [Mus musculus] 214240 6629 0.01 0.013333333 0.415037499 Up 0.080089511 Disp2 dispatched homolog 2 (Drosophila) K10649|1|2e-45|188|tsp:Tsp_06730|tripartite motif-containing protein 9/67;K18730|2|2e-07|60.8|bfo:BRAFLDRAFT_118428|PERQ amino acid-rich with GYF domain-containing protein GO:0031224//intrinsic component of membrane - - gi|24528557|ref|NP_733481.1|/0/protein dispatched homolog 2 [Mus musculus] 16008 933 0.063333333 0.06 -0.078002512 Down 0.080089511 Igfbp2 insulin-like growth factor binding protein 2 K10138|1|1e-10|69.7|lcm:102347870|insulin-like growth factor-binding protein 3 GO:0044459;GO:0031982//vesicle;GO:0044421;GO:0044459;GO:0031982//vesicle;GO:0044421 GO:0005520//insulin-like growth factor binding;GO:0005520//insulin-like growth factor binding GO:0044703;GO:0010038//response to metal ion;GO:0016049//cell growth;GO:0043627//response to estrogen;GO:0031667//response to nutrient levels;GO:0042102//positive regulation of T cell proliferation;GO:0044767//single-organism developmental process;GO:0009966//regulation of signal transduction;GO:0031960//response to corticosteroid;GO:0044703;GO:0010038//response to metal ion;GO:0016049//cell growth;GO:0043627//response to estrogen;GO:0031667//response to nutrient levels;GO:0042102//positive regulation of T cell proliferation;GO:0044767//single-organism developmental process;GO:0009966//regulation of signal transduction;GO:0031960//response to corticosteroid "gi|148667874|gb|EDL00291.1|/8.60575e-103/insulin-like growth factor binding protein 2, isoform CRA_a, partial [Mus musculus]" 13487 2911 0.036666667 0.04 0.125530882 Up 0.080089511 Slc26a3 "solute carrier family 26, member 3" "K14078|1|0.0|1246|mmu:13487|solute carrier family 26 (chloride anion exchanger), member 3" GO:0044459;GO:0005903//brush border;GO:0016021//integral component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0015103//inorganic anion transmembrane transporter activity GO:0015698//inorganic anion transport;GO:0044763 gi|10946676|ref|NP_067328.1|/0/chloride anion exchanger [Mus musculus] 22754 5783 0.043333333 0.046666667 0.106915204 Up 0.080089511 Zfp92 zinc finger protein 92 K09228|1|0.0|993|mmu:22754|KRAB domain-containing zinc finger protein GO:0043231//intracellular membrane-bounded organelle;GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding;GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated;GO:0006351//transcription, DNA-templated" gi|84370221|ref|NP_033592.2|/0/zinc finger protein 92 isoform 1 [Mus musculus] 18037 2370 0.776666667 0.776666667 0 - 0.080089511 Nfkbie "nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon" K05872|1|0.0|655|mmu:18037|NF-kappa-B inhibitor epsilon GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part - "GO:0006351//transcription, DNA-templated;GO:0032329" gi|756761801|ref|NP_001291885.1|/2.98762e-177/NF-kappa-B inhibitor epsilon isoform 2 [Mus musculus] 320202 2494 0.046666667 0.046666667 0 - 0.080089511 Lefty2 left-right determination factor 2 K04668|1|0.0|692|xla:100505435|left-right determination factor - - - - 69349 925 0.113333333 0.113333333 0 - 0.080089511 1700008O03Rik RIKEN cDNA 1700008O03 gene - - - - "gi|148690769|gb|EDL22716.1|/5.99432e-117/mCG134545, isoform CRA_c, partial [Mus musculus]" 57249 4943 0.01 0.01 0 - 0.080089511 Gabrq "gamma-aminobutyric acid (GABA) A receptor, subunit theta" K05192|1|0.0|1001|mmu:57249|gamma-aminobutyric acid receptor subunit theta - - - - 11556 2795 0.036666667 0.033333333 -0.137503524 Down 0.080089511 Adrb3 "adrenergic receptor, beta 3" K04143|1|0.0|654|mmu:11556|adrenergic receptor beta-3 GO:0043231//intracellular membrane-bounded organelle;GO:0031224//intrinsic component of membrane;GO:0043234//protein complex GO:0031690//adrenergic receptor binding;GO:0042802//identical protein binding;GO:1901338;GO:0004939//beta-adrenergic receptor activity GO:0001659//temperature homeostasis;GO:0001993//regulation of systemic arterial blood pressure by norepinephrine-epinephrine;GO:0045762//positive regulation of adenylate cyclase activity;GO:0009636//response to toxic substance;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0045444//fat cell differentiation;GO:0000165//MAPK cascade;GO:0006897//endocytosis;GO:0002021//response to dietary excess;GO:0044767//single-organism developmental process;GO:0006950//response to stress;GO:0007631//feeding behavior;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway gi|85861166|ref|NP_038490.2|/0/beta-3 adrenergic receptor [Mus musculus] 625901 1804 0.036666667 0.033333333 -0.137503524 Down 0.080089511 Gm6634 predicted gene 6634 - - - - gi|537139243|gb|ERE67428.1|/1.14312e-13/hypothetical protein H671_7g18744 [Cricetulus griseus] 240069 3710 0.043333333 0.04 -0.115477217 Down 0.080089511 Morc2b microrchidia 2B - - GO:0046914//transition metal ion binding;GO:0032550 - gi|255003782|ref|NP_808387.2|/0/MORC family CW-type zinc finger protein 2B [Mus musculus] 228846 3941 2.246666667 2.25 0.002138911 Up 0.080089511 D630003M21Rik RIKEN cDNA D630003M21 gene K05625|1|2e-17|94.7|fpg:101910367|transglutaminase 2 [EC:2.3.2.13];K08810|2|1e-13|82.0|cel:CELE_F55C7.7|triple functional domain protein [EC:2.7.11.1];K15048|4|5e-13|80.1|cbr:CBG12077|kalirin [EC:2.7.11.1] - - - gi|262263358|ref|NP_808325.2|/0/uncharacterized protein KIAA1755 homolog isoform 1 [Mus musculus] 382571 4819 0.016666667 0.016666667 0 - 0.080089511 Kcnf1 "potassium voltage-gated channel, subfamily F, member 1" K04899|1|0.0|976|mmu:382571|potassium voltage-gated channel subfamily F member 1 - - - gi|237513011|ref|NP_963289.2|/0/potassium voltage-gated channel subfamily F member 1 [Mus musculus] 236727 2469 0.343333333 0.34 -0.014075185 Down 0.080089511 Slc9a7 "solute carrier family 9 (sodium/hydrogen exchanger), member 7" "K12041|1|0.0|1190|mmu:236727|solute carrier family 9 (sodium/hydrogen exchanger), member 6/7" GO:0031224//intrinsic component of membrane;GO:0010008//endosome membrane GO:0005451//monovalent cation:proton antiporter activity GO:0006814//sodium ion transport;GO:0044763;GO:0055067 "gi|148668435|gb|EDL00759.1|/0/solute carrier family 9 (sodium/hydrogen exchanger), isoform 7, isoform CRA_b, partial [Mus musculus]" 70579 4426.02 18.54 18.53666667 -0.000259408 Down 0.080089511 Zc3h11a zinc finger CCCH type containing 11A K14961|1|6e-70|269|tgu:100219766|COMPASS component SWD1;K10779|2|8e-06|56.2|cel:CELE_B0041.7|transcriptional regulator ATRX [EC:3.6.4.12] - GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding;GO:0097159//organic cyclic compound binding;GO:0046914//transition metal ion binding - gi|115270986|ref|NP_653113.4|/0/zinc finger CCCH domain-containing protein 11A [Mus musculus] 19143 4017 0.166666667 0.17 0.028569152 Up 0.080089511 St14 suppression of tumorigenicity 14 (colon carcinoma) K08670|1|0.0|1759|mmu:19143|suppressor of tumorigenicity protein 14 [EC:3.4.21.109] GO:0044421;GO:0044459;GO:0019898//extrinsic component of membrane;GO:0016021//integral component of membrane GO:0004175//endopeptidase activity GO:0048870//cell motility;GO:0019538//protein metabolic process gi|7363445|ref|NP_035306.2|/0/suppressor of tumorigenicity 14 protein homolog [Mus musculus] 22423 3376 0.023333333 0.02 -0.222392421 Down 0.080089511 Wnt8b "wingless-type MMTV integration site family, member 8B" "K00714|1|0.0|713|mmu:22423|wingless-type MMTV integration site family, member 8" - - - gi|225637542|ref|NP_035850.2|/0/protein Wnt-8b [Mus musculus] 207777 7633 0.01 0.013333333 0.415037499 Up 0.080089511 Bzrap1 benzodiazepine receptor associated protein 1 K19922|1|0.0|3283|mmu:207777|peripheral-type benzodiazepine receptor-associated protein 1 - - - gi|568972653|ref|XP_006532767.1|/0/PREDICTED: peripheral-type benzodiazepine receptor-associated protein 1 isoform X1 [Mus musculus] 213006 2871.62 4.766666667 4.766666667 0 - 0.080089511 Mfsd4a major facilitator superfamily domain containing 4A "K08175|1|1e-34|151|cin:100181339|MFS transporter, FHS family, Na+ dependent glucose transporter 1" GO:0031224//intrinsic component of membrane;GO:0031224//intrinsic component of membrane - GO:0051234//establishment of localization;GO:0044763;GO:0051234//establishment of localization;GO:0044763 gi|26332881|dbj|BAC30158.1|/0/unnamed protein product [Mus musculus] 329693 2466 0.026666667 0.026666667 0 - 0.080089511 Fcrl5 Fc receptor-like 5 K06727|1|0.0|1185|mmu:329693|Fc receptor-like protein GO:0031224//intrinsic component of membrane;GO:0016020//membrane - - gi|164420687|ref|NP_899045.3|/0/Fc receptor-like protein 5 isoform a precursor [Mus musculus] 15561 2071 0.05 0.046666667 -0.099535674 Down 0.080089511 Htr3a 5-hydroxytryptamine (serotonin) receptor 3A K04819|1|0.0|937|mmu:15561|5-hydroxytryptamine receptor 3 GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0044424;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0044297//cell body;GO:0097060//synaptic membrane;GO:0044424 GO:0043169//cation binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0005267//potassium channel activity;GO:0043169//cation binding;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0005267//potassium channel activity GO:0097305//response to alcohol;GO:0007267//cell-cell signaling;GO:0070848//response to growth factor;GO:0044765//single-organism transport;GO:0014070//response to organic cyclic compound;GO:0007186//G-protein coupled receptor signaling pathway;GO:0097305//response to alcohol;GO:0007267//cell-cell signaling;GO:0070848//response to growth factor;GO:0044765//single-organism transport;GO:0014070//response to organic cyclic compound;GO:0007186//G-protein coupled receptor signaling pathway gi|153791845|ref|NP_001093114.1|/0/5-hydroxytryptamine receptor 3A isoform 2 precursor [Mus musculus] 271278 2656 0.033333333 0.036666667 0.137503524 Up 0.080089511 BC024139 cDNA sequence BC024139 K19827|1|8e-17|92.0|acs:103281665|microtuble-actin crosslinking factor 1;K10382|5|4e-10|69.7|aag:AaeL_AAEL002829|dystonin - - - "gi|148697583|gb|EDL29530.1|/0/cDNA sequence BC024139, isoform CRA_c, partial [Mus musculus]" 385668 3170 0.14 0.143333333 0.033947332 Up 0.080089511 Lca5l Leber congenital amaurosis 5-like K10421|1|3e-09|67.0|chx:102190721|CAP-Gly domain-containing linker protein 1 - - - gi|568997598|ref|XP_006523125.1|/0/PREDICTED: lebercilin-like protein isoform X3 [Mus musculus] 100061 2773 0.103333333 0.103333333 0 - 0.080089511 Lrrc19 leucine rich repeat containing 19 K18808|1|8e-17|92.0|bfo:BRAFLDRAFT_73275|toll-like receptor 13;K13023|2|4e-16|89.7|lcm:102345459|carboxypeptidase N regulatory subunit;K05401|4|2e-15|87.4|spu:593135|toll-like receptor 3;K08462|5|3e-15|87.0|fch:102047619|G protein-coupled receptor 125 GO:0031224//intrinsic component of membrane - - "gi|148698988|gb|EDL30935.1|/0/leucine rich repeat containing 19, isoform CRA_b, partial [Mus musculus]" 195359 2095 0.03 0.03 0 - 0.080089511 Trim40 tripartite motif-containing 40 K12016|1|5e-118|427|mmu:195359|tripartite motif-containing protein 40 GO:0044464;GO:0044464 GO:0046914//transition metal ion binding;GO:0046914//transition metal ion binding - gi|84794619|ref|NP_001028407.1|/2.03683e-140/tripartite motif-containing protein 40 isoform 1 [Mus musculus] 76645 7386 0.01 0.013333333 0.415037499 Up 0.080089511 Pkd1l2 polycystic kidney disease 1 like 2 K04988|1|0.0|4756|mmu:76645|polycystin 1L2 GO:0031224//intrinsic component of membrane GO:0046872//metal ion binding GO:0007186//G-protein coupled receptor signaling pathway gi|294862233|ref|NP_083962.4|/0/polycystic kidney disease protein 1-like 2 precursor [Mus musculus] 76413 1266 0.276666667 0.28 0.017277991 Up 0.080089511 1700016D06Rik RIKEN cDNA 1700016D06 gene - - - - gi|21313198|ref|NP_077233.1|/4.36265e-64/uncharacterized protein LOC76413 precursor [Mus musculus] 116852 1306 0.043333333 0.043333333 0 - 0.080089511 Akr1c20 "aldo-keto reductase family 1, member C20" K04119|1|2e-109|398|mcf:102142023|aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357] GO:0043231//intracellular membrane-bounded organelle;GO:0044444//cytoplasmic part "GO:0043168//anion binding;GO:0047023//androsterone dehydrogenase activity;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0005496//steroid binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0016651//oxidoreductase activity, acting on NAD(P)H" GO:0009753//response to jasmonic acid;GO:0030647;GO:0048545//response to steroid hormone;GO:0051259//protein oligomerization;GO:0001523//retinoid metabolic process;GO:0044707;GO:0008207//C21-steroid hormone metabolic process "gi|902763365|ref|NP_001298061.1|/0/aldo-keto reductase family 1, member C20 isoform 1 [Mus musculus]" 613258 2375 4.82 4.816666667 -0.00099806 Down 0.080089511 A730017L22Rik RIKEN cDNA A730017L22 gene K11290|1|1e-10|71.6|rno:317165|template-activating factor I GO:0043005//neuron projection;GO:0044421 GO:0032934//sterol binding;GO:0042802//identical protein binding;GO:0043169//cation binding;GO:0071813//lipoprotein particle binding GO:0010742//macrophage derived foam cell differentiation;GO:0002526//acute inflammatory response;GO:0051592//response to calcium ion;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0043623//cellular protein complex assembly;GO:0097305//response to alcohol;GO:0010976//positive regulation of neuron projection development;GO:0010883//regulation of lipid storage gi|45478228|gb|AAS66285.1|/3.78255e-80/LRRGT00194 [Rattus norvegicus] 26875 20099 0.043333333 0.046666667 0.106915204 Up 0.080089511 Pclo piccolo (presynaptic cytomatrix protein) K16882|1|0.0|7083|mmu:26875|protein piccolo - GO:0005543//phospholipid binding;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005515//protein binding GO:0006996//organelle organization;GO:0006903//vesicle targeting;GO:0006887//exocytosis;GO:0030072//peptide hormone secretion;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0006996//organelle organization;GO:0006903//vesicle targeting;GO:0006887//exocytosis;GO:0030072//peptide hormone secretion;GO:0019935//cyclic-nucleotide-mediated signaling gi|160707978|ref|NP_001104266.1|/0/protein piccolo isoform 2 [Mus musculus] 29873 3800 0.053333333 0.053333333 0 - 0.080089511 Cspg5 chondroitin sulfate proteoglycan 5 K08116|1|0.0|960|mmu:29873|chondroitin sulfate proteoglycan 5 GO:0000139//Golgi membrane;GO:0005764//lysosome;GO:0016021//integral component of membrane;GO:0031224//intrinsic component of membrane;GO:0000139//Golgi membrane GO:0005102//receptor binding GO:0006810//transport;GO:0040007//growth;GO:0006027//glycosaminoglycan catabolic process;GO:0007409//axonogenesis;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0044238//primary metabolic process;GO:0007268//chemical synaptic transmission;GO:0040007//growth;GO:0007268//chemical synaptic transmission;GO:0007409//axonogenesis gi|261878591|ref|NP_038912.3|/0/chondroitin sulfate proteoglycan 5 isoform a precursor [Mus musculus] 20564 5017 2.393333333 2.39 -0.002010725 Down 0.080089511 Slit3 slit homolog 3 (Drosophila) K06850|1|0.0|3067|mmu:20564|slit 3 - - - - 100040049 935 0.113333333 0.11 -0.043068722 Down 0.080089511 1810010D01Rik RIKEN cDNA 1810010D01 gene - - - - gi|21553343|ref|NP_659556.1|/7.68019e-35/mammary cancer associated protein RMT-1 [Rattus norvegicus] 232889 3374 0.02 0.02 0 - 0.080089511 Pla2g4c "phospholipase A2, group IVC (cytosolic, calcium-independent)" K16342|1|0.0|1213|mmu:232889|cytosolic phospholipase A2 [EC:3.1.1.4] - GO:0004623//phospholipase A2 activity;GO:0004623//phospholipase A2 activity GO:0006650//glycerophospholipid metabolic process;GO:0006650//glycerophospholipid metabolic process gi|52317152|ref|NP_001004762.1|/0/cytosolic phospholipase A2 gamma isoform 2 [Mus musculus] 21462 2065 0.03 0.03 0 - 0.080089511 Tcp10b t-complex protein 10b K11502|1|3e-84|315|amj:102561979|centromere protein J - - - gi|568998138|ref|XP_006523342.1|/0/PREDICTED: t-complex protein 10c isoform X3 [Mus musculus] 216177 2634 0.113333333 0.11 -0.043068722 Down 0.080089511 AU041133 expressed sequence AU041133 K09228|1|0.0|1093|mmu:216177|KRAB domain-containing zinc finger protein GO:0044464 GO:0046914//transition metal ion binding "GO:0006351//transcription, DNA-templated" gi|251823944|ref|NP_001156536.1|/0/uncharacterized protein LOC216177 [Mus musculus] 237716 2938 0.023333333 0.023333333 0 - 0.080089511 Gpr75 G protein-coupled receptor 75 K08417|1|0.0|1003|mmu:237716|G protein-coupled receptor 75 GO:0016021//integral component of membrane GO:0004888//transmembrane signaling receptor activity GO:0007166//cell surface receptor signaling pathway gi|47059091|ref|NP_780699.2|/0/probable G-protein coupled receptor 75 [Mus musculus] 332175 1278 0.046666667 0.043333333 -0.106915204 Down 0.080089511 Zdhhc23 "zinc finger, DHHC domain containing 23" K18932|1|0.0|757|mmu:332175|palmitoyltransferase [EC:2.3.1.225] GO:0031224//intrinsic component of membrane GO:0046914//transition metal ion binding;GO:0016740//transferase activity GO:0006497//protein lipidation;GO:0007009//plasma membrane organization gi|74184789|dbj|BAE27992.1|/0/unnamed protein product [Mus musculus] 218333 7675 3.843333333 3.84 -0.001251796 Down 0.080089511 Ice1 interactor of little elongation complex ELL subunit 1 - - - - gi|256818804|ref|NP_659086.2|/0/little elongation complex subunit 1 [Mus musculus] 78600 574 0.096666667 0.096666667 0 - 0.080089511 Pde6h "phosphodiesterase 6H, cGMP-specific, cone, gamma" "K13760|1|6e-34|145|gja:107118917|retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma" - "GO:0030551//cyclic nucleotide binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity" GO:0006468//protein phosphorylation;GO:0050953//sensory perception of light stimulus;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway "gi|927131730|ref|XP_013853260.1|/3.2152e-33/PREDICTED: retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma isoform X1 [Sus scrofa]" 19200 1853 1.173333333 1.17 -0.004104398 Down 0.080089511 Pstpip1 proline-serine-threonine phosphatase-interacting protein 1 K12804|1|0.0|725|mmu:19200|proline-serine-threonine phosphatase interacting protein 1 GO:0032432//actin filament bundle;GO:0032155 GO:0019902//phosphatase binding;GO:0008092//cytoskeletal protein binding;GO:0003824//catalytic activity GO:0022610;GO:0044710 gi|171184423|ref|NP_035323.2|/0/proline-serine-threonine phosphatase-interacting protein 1 [Mus musculus] 18781 1618 0.093333333 0.09 -0.05246742 Down 0.080089511 Pla2g2c "phospholipase A2, group IIC" K01047|1|7e-78|293|mmu:18781|secretory phospholipase A2 [EC:3.1.1.4] - GO:0046872//metal ion binding;GO:0004623//phospholipase A2 activity GO:0006644//phospholipid metabolic process gi|225543511|ref|NP_032894.2|/6.325e-77/group IIC secretory phospholipase A2 precursor [Mus musculus] 20311 1656 0.036666667 0.033333333 -0.137503524 Down 0.080089511 Cxcl5 chemokine (C-X-C motif) ligand 5 K05506|1|4e-58|228|mmu:20311|C-X-C motif chemokine 5/6 GO:0044421 GO:0005125//cytokine activity GO:0032496//response to lipopolysaccharide;GO:0070945//neutrophil mediated killing of gram-negative bacterium;GO:0010975//regulation of neuron projection development;GO:0007259//JAK-STAT cascade;GO:0001817//regulation of cytokine production;GO:0007420//brain development;GO:0009887//organ morphogenesis;GO:0010212//response to ionizing radiation gi|114842398|ref|NP_033167.2|/3.36343e-57/C-X-C motif chemokine 5 precursor [Mus musculus] 27411 2054 0.023333333 0.026666667 0.192645078 Up 0.080089511 Slc14a2 "solute carrier family 14 (urea transporter), member 2" K08716|1|0.0|1491|rno:54302|solute carrier family 14 (urea transporter) GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane;GO:0044459;GO:0031224//intrinsic component of membrane GO:0042887;GO:0042887;GO:0042887;GO:0042887 GO:0015840//urea transport;GO:0006950//response to stress;GO:0015840//urea transport;GO:0006950//response to stress;GO:0015840//urea transport;GO:0006950//response to stress;GO:0015840//urea transport;GO:0006950//response to stress gi|159131880|ref|NP_997534.2|/0/urea transporter 2 isoform a [Mus musculus] 619665 2970 0.036666667 0.036666667 0 - 0.080089511 Klf14 Kruppel-like factor 14 K09208|1|3e-157|558|mmu:619665|krueppel-like factor 9/13/14/16 GO:0043231//intracellular membrane-bounded organelle GO:0046914//transition metal ion binding;GO:0003676//nucleic acid binding "GO:0006351//transcription, DNA-templated" gi|205360920|ref|NP_001128565.1|/2.22024e-156/Krueppel-like factor 14 [Mus musculus] 69974 1549 0.036666667 0.036666667 0 - 0.080089511 2810405F15Rik RIKEN cDNA 2810405F15 gene - - - - gi|148695938|gb|EDL27885.1|/1.88548e-14/mCG1040288 [Mus musculus] 77629 6512 0.013333333 0.013333333 0 - 0.080089511 Sphkap "SPHK1 interactor, AKAP domain containing" K16527|1|3e-27|128|lcm:102363363|A-kinase anchor protein 11 GO:0031674//I band;GO:0043231//intracellular membrane-bounded organelle GO:0005515//protein binding - gi|170014712|ref|NP_766018.3|/0/A-kinase anchor protein SPHKAP [Mus musculus] 17883 5992 0.016666667 0.013333333 -0.321928095 Down 0.080089511 Myh3 "myosin, heavy polypeptide 3, skeletal muscle, embryonic" K10352|1|0.0|3406|mmu:17883|myosin heavy chain GO:0016459//myosin complex;GO:0043292//contractile fiber GO:0008092//cytoskeletal protein binding;GO:0032550 - gi|153792649|ref|NP_001093105.1|/0/myosin-3 [Mus musculus] 319586 4187 0.073333333 0.076666667 0.064130337 Up 0.080089511 Celf5 "CUGBP, Elav-like family member 5" K13207|1|0.0|796|mmu:319586|CUG-BP- and ETR3-like factor - - - "gi|148699458|gb|EDL31405.1|/0/mCG145499, partial [Mus musculus]" 212281 5180 0.473333333 0.47 -0.010195767 Down 0.080089511 Zfp729a zinc finger protein 729a K09228|1|0.0|2103|mmu:212281|KRAB domain-containing zinc finger protein - - - - 665033 9297 0.013333333 0.01 -0.415037499 Down 0.080089511 Col6a5 "collagen, type VI, alpha 5" "K06238|1|0.0|2916|mmu:665033|collagen, type VI, alpha" - - - gi|816380041|sp|A6H584.4|CO6A5_MOUSE/0/RecName: Full=Collagen alpha-5(VI) chain; AltName: Full=Collagen alpha-1(XXIX) chain; Flags: Precursor 227929 5735 0.423333333 0.426666667 0.011315313 Up 0.080089511 Cytip cytohesin 1 interacting protein K04465|1|6e-15|87.0|ccw:104683590|nuclear receptor subfamily 4 group A member 1;K08789|2|6e-09|67.0|dre:100535762|microtubule-associated serine/threonine kinase [EC:2.7.11.1] GO:0005768//endosome - GO:0007155//cell adhesion gi|21105855|ref|NP_631939.1|/3.04625e-176/cytohesin-interacting protein [Mus musculus] 619310 2960 0.056666667 0.053333333 -0.087462841 Down 0.080089511 Zfp872 zinc finger protein 872 K09228|1|0.0|1004|mmu:619310|KRAB domain-containing zinc finger protein GO:0005622//intracellular GO:0046872//metal ion binding "GO:0006351//transcription, DNA-templated" gi|85702145|ref|NP_001028985.1|/0/zinc finger protein 564 [Mus musculus] 381002 771 0.136666667 0.136666667 0 - 0.080089511 Gm5144 predicted gene 5144 - - - - - 432611 2871 0.023333333 0.02 -0.222392421 Down 0.080089511 Dnaic2 "dynein, axonemal, intermediate chain 2" "K11143|1|0.0|1005|mmu:432611|dynein intermediate chain 2, axonemal" GO:0030286//dynein complex;GO:0005930//axoneme GO:0005488//binding;GO:0003774//motor activity GO:0010927 "gi|114145546|ref|NP_001030050.2|/0/dynein intermediate chain 2, axonemal [Mus musculus]" 58991 507 0.206666667 0.203333333 -0.023458973 Down 0.080089511 Ghrl ghrelin K05254|1|6e-52|205|mmu:58991|ghrelin GO:0043005//neuron projection;GO:0044424;GO:0044421;GO:0043005//neuron projection;GO:0044424;GO:0044421;GO:0043005//neuron projection;GO:0044424;GO:0044421;GO:0043005//neuron projection;GO:0044424;GO:0044421 GO:0001664//G-protein coupled receptor binding;GO:0005179//hormone activity;GO:0030295//protein kinase activator activity;GO:0001664//G-protein coupled receptor binding;GO:0005179//hormone activity;GO:0030295//protein kinase activator activity;GO:0001664//G-protein coupled receptor binding;GO:0005179//hormone activity;GO:0030295//protein kinase activator activity;GO:0001664//G-protein coupled receptor binding;GO:0005179//hormone activity;GO:0030295//protein kinase activator activity "GO:0006954//inflammatory response;GO:0007015//actin filament organization;GO:0001935//endothelial cell proliferation;GO:0006915//apoptotic process;GO:0007631//feeding behavior;GO:0032611//interleukin-1 beta production;GO:0007416//synapse assembly;GO:0051899//membrane depolarization;GO:0001893//maternal placenta development;GO:0022600//digestive system process;GO:0031175//neuron projection development;GO:0030252//growth hormone secretion;GO:0042748//circadian sleep/wake cycle, non-REM sleep;GO:0032097//positive regulation of response to food;GO:0051458//corticotropin secretion;GO:0042036//negative regulation of cytokine biosynthetic process;GO:0007166//cell surface receptor signaling pathway;GO:0048545//response to steroid hormone;GO:0007632//visual behavior;GO:0050796//regulation of insulin secretion;GO:0040011//locomotion;GO:0045860//positive regulation of protein kinase activity;GO:0043400//cortisol secretion;GO:0042320//regulation of circadian sleep/wake cycle, REM sleep;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0006954//inflammatory response;GO:0007015//actin filament organization;GO:0001935//endothelial cell proliferation;GO:0006915//apoptotic process;GO:0007631//feeding behavior;GO:0032611//interleukin-1 beta production;GO:0007416//synapse assembly;GO:0051899//membrane depolarization;GO:0001893//maternal placenta development;GO:0022600//digestive system process;GO:0031175//neuron projection development;GO:0030252//growth hormone secretion;GO:0042748//circadian sleep/wake cycle, non-REM sleep;GO:0032097//positive regulation of response to food;GO:0051458//corticotropin secretion;GO:0042036//negative regulation of cytokine biosynthetic process;GO:0007166//cell surface receptor signaling pathway;GO:0048545//response to steroid hormone;GO:0007632//visual behavior;GO:0050796//regulation of insulin secretion;GO:0040011//locomotion;GO:0045860//positive regulation of protein kinase activity;GO:0043400//cortisol secretion;GO:0042320//regulation of circadian sleep/wake cycle, REM sleep;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0006954//inflammatory response;GO:0007015//actin filament organization;GO:0001935//endothelial cell proliferation;GO:0006915//apoptotic process;GO:0007631//feeding behavior;GO:0032611//interleukin-1 beta production;GO:0007416//synapse assembly;GO:0051899//membrane depolarization;GO:0001893//maternal placenta development;GO:0022600//digestive system process;GO:0031175//neuron projection development;GO:0030252//growth hormone secretion;GO:0042748//circadian sleep/wake cycle, non-REM sleep;GO:0032097//positive regulation of response to food;GO:0051458//corticotropin secretion;GO:0042036//negative regulation of cytokine biosynthetic process;GO:0007166//cell surface receptor signaling pathway;GO:0048545//response to steroid hormone;GO:0007632//visual behavior;GO:0050796//regulation of insulin secretion;GO:0040011//locomotion;GO:0045860//positive regulation of protein kinase activity;GO:0043400//cortisol secretion;GO:0042320//regulation of circadian sleep/wake cycle, REM sleep;GO:0051480//regulation of cytosolic calcium ion concentration;GO:0006954//inflammatory response;GO:0007015//actin filament organization;GO:0001935//endothelial cell proliferation;GO:0006915//apoptotic process;GO:0007631//feeding behavior;GO:0032611//interleukin-1 beta production;GO:0007416//synapse assembly;GO:0051899//membrane depolarization;GO:0001893//maternal placenta development;GO:0022600//digestive system process;GO:0031175//neuron projection development;GO:0030252//growth hormone secretion;GO:0042748//circadian sleep/wake cycle, non-REM sleep;GO:0032097//positive regulation of response to food;GO:0051458//corticotropin secretion;GO:0042036//negative regulation of cytokine biosynthetic process;GO:0007166//cell surface receptor signaling pathway;GO:0048545//response to steroid hormone;GO:0007632//visual behavior;GO:0050796//regulation of insulin secretion;GO:0040011//locomotion;GO:0045860//positive regulation of protein kinase activity;GO:0043400//cortisol secretion;GO:0042320//regulation of circadian sleep/wake cycle, REM sleep;GO:0051480//regulation of cytosolic calcium ion concentration" gi|557357759|ref|NP_001273334.1|/1.00476e-26/uncharacterized protein LOC58991 isoform 3 precursor [Mus musculus] 399599 3163 0.023333333 0.02 -0.222392421 Down 0.080089511 Ccdc87 coiled-coil domain containing 87 K01373|1|2e-109|399|aml:100483888|cathepsin F [EC:3.4.22.41] - - - - 13419 1309 1.713333333 1.71 -0.002809534 Down 0.080089511 Dnase1 deoxyribonuclease I K11994|1|3e-141|504|mmu:13419|deoxyribonuclease-1 [EC:3.1.21.1] GO:0012505//endomembrane system;GO:0043231//intracellular membrane-bounded organelle "GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters" GO:0006259//DNA metabolic process;GO:0012501//programmed cell death "gi|148664803|gb|EDK97219.1|/1.34831e-140/deoxyribonuclease I, isoform CRA_a, partial [Mus musculus]" 14069 7306.23 0.233333333 0.236666667 0.020464103 Up 0.080089511 F8 coagulation factor VIII K03899|1|0.0|4535|mmu:14069|coagulation factor VIII GO:0044421;GO:0044421;GO:0044421 GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity;GO:0046914//transition metal ion binding;GO:0003824//catalytic activity GO:0007599//hemostasis;GO:0002526//acute inflammatory response;GO:0072376//protein activation cascade;GO:0001775//cell activation;GO:0022610;GO:0044710;GO:0007599//hemostasis;GO:0002526//acute inflammatory response;GO:0072376//protein activation cascade;GO:0001775//cell activation;GO:0022610;GO:0044710;GO:0007599//hemostasis;GO:0002526//acute inflammatory response;GO:0072376//protein activation cascade;GO:0001775//cell activation;GO:0022610;GO:0044710 gi|238624184|ref|NP_001154846.1|/0/coagulation factor VIII isoform 3 precursor [Mus musculus] 75426 2729 0.126666667 0.13 0.037474705 Up 0.080089511 Igfbpl1 insulin-like growth factor binding protein-like 1 K08786|1|1e-15|88.2|bta:514946|HtrA serine peptidase 4 [EC:3.4.21.-];K08784|3|1e-13|81.3|xtr:100488607|HtrA serine peptidase 1 [EC:3.4.21.-];K08785|5|1e-12|78.2|acs:100560592|HtrA serine peptidase 3 [EC:3.4.21.-] - GO:0019838//growth factor binding - gi|9055246|ref|NP_061211.1|/2.64702e-124/insulin-like growth factor-binding protein-like 1 precursor [Mus musculus] 215772 5212 0.016666667 0.013333333 -0.321928095 Down 0.080089511 Adgb androglobin K08576|1|2e-12|78.2|cbr:CBG18007|calpain-7 [EC:3.4.22.-] - - - - 233271 5274 0.036666667 0.036666667 0 - 0.080089511 Luzp2 leucine zipper protein 2 K19533|1|1e-08|65.9|lcm:102362104|synaptonemal complex protein 1;K20283|3|4e-07|60.8|pbi:103056545|golgin subfamily A member 4;K20478|4|7e-07|60.1|dre:557772|golgin subfamily B member 1 - - - gi|134053919|ref|NP_848820.4|/1.69258e-173/leucine zipper protein 2 precursor [Mus musculus] 75404 3039 0.05 0.046666667 -0.099535674 Down 0.080089511 Arhgap36 Rho GTPase activating protein 36 K20315|1|2e-18|97.8|sko:102803527|Rho GTPase-activating protein 21/23 GO:0044464 GO:0008047//enzyme activator activity GO:0007154//cell communication gi|124487453|ref|NP_001074592.1|/0/rho GTPase-activating protein 36 [Mus musculus] 330902 1986 0.03 0.026666667 -0.169925001 Down 0.080089511 Gm16853 "predicted gene, 16853" - - - - - 268354 4152 0.026666667 0.023333333 -0.192645078 Down 0.080089511 Fam19a2 "family with sequence similarity 19, member A2" - GO:0044424;GO:0044424;GO:0044424 - - gi|731260861|ref|XP_010642845.1|/1.84623e-82/PREDICTED: protein FAM19A2 isoform X1 [Fukomys damarensis] 246316 6291 0.416666667 0.416666667 -1.60E-16 Down 0.080089511 Lgi2 "leucine-rich repeat LGI family, member 2" K19999|1|2e-148|530|lcm:102367021|leucine-rich repeat LGI family member 3 - - - gi|21450363|ref|NP_659194.1|/0/leucine-rich repeat LGI family member 2 isoform 1 precursor [Mus musculus] 71804 2307 0.443333333 0.446666667 0.010806755 Up 0.080089511 Mtfr2 mitochondrial fission regulator 2 K13087|1|8e-53|211|gga:421691|bcl2 associated transcription factor 1 GO:0031981//nuclear lumen - "GO:0006974//cellular response to DNA damage stimulus;GO:0043068//positive regulation of programmed cell death;GO:0097193//intrinsic apoptotic signaling pathway;GO:0045333//cellular respiration;GO:0007005//mitochondrion organization;GO:0045893//positive regulation of transcription, DNA-templated" gi|190570190|ref|NP_082206.2|/0/mitochondrial fission regulator 2 [Mus musculus] 14619 2404 0.026666667 0.026666667 0 - 0.080089511 Gjb2 "gap junction protein, beta 2" "K07621|1|9e-132|473|mmu:14619|gap junction protein, beta 2" GO:0031224//intrinsic component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0044459;GO:0005921//gap junction GO:0005488//binding;GO:0022829//wide pore channel activity GO:0007043//cell-cell junction assembly;GO:0050954//sensory perception of mechanical stimulus;GO:0046546//development of primary male sexual characteristics;GO:0051234//establishment of localization;GO:0007154//cell communication "gi|148704234|gb|EDL36181.1|/1.27628e-167/gap junction membrane channel protein beta 2, isoform CRA_b, partial [Mus musculus]" 58869 4774 0.033333333 0.033333333 0 - 0.080089511 Pex5l peroxisomal biogenesis factor 5-like K13342|1|0.0|1102|mcf:101926179|peroxin-5 GO:0043005//neuron projection;GO:0034703//cation channel complex;GO:0060187//cell pole;GO:0044444//cytoplasmic part GO:0005217//intracellular ligand-gated ion channel activity;GO:0017016//Ras GTPase binding GO:0051458//corticotropin secretion;GO:0006887//exocytosis;GO:0008104//protein localization;GO:0009966//regulation of signal transduction;GO:0006873//cellular ion homeostasis gi|254553496|ref|NP_001156988.1|/0/PEX5-related protein isoform 2 [Mus musculus] 76024 1148 0.093333333 0.09 -0.05246742 Down 0.080089511 Gm11346 X-linked lymphocyte-regulated 5 pseudogene K19528|1|3e-14|53.5|phd:102339419|synaptonemal complex protein 3 - - - - 69142 1109 0.05 0.05 0 - 0.080089511 Cd209f CD209f antigen K06563|1|1e-129|465|mmu:69142|CD209 antigen - GO:0005488//binding - "gi|112180743|gb|AAH21323.1|/2.90798e-143/Cd209f protein, partial [Mus musculus]" 18601 3068 0.036666667 0.036666667 0 - 0.080089511 Padi3 "peptidyl arginine deiminase, type III" K01481|1|0.0|1349|mmu:18601|protein-arginine deiminase [EC:3.5.3.15] GO:0031981//nuclear lumen "GO:0016813//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines;GO:0046872//metal ion binding" GO:0006527//arginine catabolic process;GO:0018195//peptidyl-arginine modification gi|156938255|ref|NP_035190.3|/0/protein-arginine deiminase type-3 [Mus musculus] 100045778 4573 0.096666667 0.1 0.0489096 Up 0.080089511 Rnf223 ring finger 223 K11983|1|2e-08|65.1|cmy:102942332|E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27];K11997|2|9e-08|62.8|nvi:100123158|tripartite motif-containing protein 2/3 - - - - 13406 2760 0.04 0.04 0 - 0.080089511 Dmp1 dentin matrix protein 1 - GO:0044424 GO:0005488//binding GO:0043062//extracellular structure organization;GO:0010810//regulation of cell-substrate adhesion;GO:0044707 gi|88900499|ref|NP_058059.2|/1.46675e-138/dentin matrix acidic phosphoprotein 1 precursor [Mus musculus] 382236 6434 0.153333333 0.15 -0.03170886 Down 0.080089511 Brwd3 bromodomain and WD repeat domain containing 3 K11798|1|0.0|3097|mmu:382236|bromodomain and WD repeat domain containing protein 1/3 - - GO:0022604//regulation of cell morphogenesis;GO:0006996//organelle organization gi|125490358|ref|NP_001074946.1|/0/bromodomain and WD repeat-containing protein 3 [Mus musculus] 330836 3730 2.846666667 2.843333333 -0.001690328 Down 0.080089511 Slc7a6 "solute carrier family 7 (cationic amino acid transporter, y+ system), member 6" "K13872|1|0.0|970|mmu:330836|solute carrier family 7 (L-type amino acid transporter), member 6" GO:0031224//intrinsic component of membrane GO:0015291//secondary active transmembrane transporter activity;GO:0046943//carboxylic acid transmembrane transporter activity GO:0046942//carboxylic acid transport gi|568957081|ref|XP_006531199.1|/0/PREDICTED: Y+L amino acid transporter 2 isoform X3 [Mus musculus] 74563 2248 0.266666667 0.27 0.017921908 Up 0.080089511 Rasgef1c "RasGEF domain family, member 1C" K17636|1|1e-22|110|amj:102569411|ral guanine nucleotide dissociation stimulator-like 2;K08020|2|4e-21|105|shr:100931445|Rap guanine nucleotide exchange factor 6;K08018|4|2e-20|103|obi:106881120|Rap guanine nucleotide exchange factor 2 GO:0044464 GO:0030695//GTPase regulator activity GO:0007264//small GTPase mediated signal transduction "gi|148701783|gb|EDL33730.1|/0/RasGEF domain family, member 1C, isoform CRA_a [Mus musculus]" 16411 4025 0.2 0.203333333 0.023846742 Up 0.080089511 Itgax integrin alpha X K06462|1|0.0|2302|mmu:16411|integrin alpha X GO:0005887//integral component of plasma membrane;GO:0009986//cell surface GO:0043169//cation binding GO:0007166//cell surface receptor signaling pathway;GO:0042098//T cell proliferation;GO:0002252 gi|47847422|dbj|BAD21383.1|/0/mFLJ00114 protein [Mus musculus] 11474 2887 0.05 0.053333333 0.093109404 Up 0.080089511 Actn3 actinin alpha 3 K05699|1|0.0|1721|mmu:11474|actinin alpha GO:0031674//I band;GO:0005924//cell-substrate adherens junction;GO:0015629//actin cytoskeleton GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0003779//actin binding GO:0007015//actin filament organization;GO:0007044//cell-substrate junction assembly;GO:0003012//muscle system process gi|7304855|ref|NP_038484.1|/0/alpha-actinin-3 [Mus musculus] 22287 468 0.116666667 0.116666667 0 - 0.080089511 Scgb1a1 "secretoglobin, family 1A, member 1 (uteroglobin)" - "GO:0016023//cytoplasmic, membrane-bounded vesicle;GO:0012505//endomembrane system;GO:0005783//endoplasmic reticulum;GO:0044421" GO:0004859//phospholipase inhibitor activity GO:0044703;GO:0007275//multicellular organism development;GO:0006366//transcription from RNA polymerase II promoter;GO:0001818//negative regulation of cytokine production;GO:0043487//regulation of RNA stability;GO:0000302//response to reactive oxygen species;GO:0044092//negative regulation of molecular function;GO:0006954//inflammatory response;GO:0010035//response to inorganic substance;GO:0031960//response to corticosteroid;GO:0002237//response to molecule of bacterial origin;GO:0042098//T cell proliferation gi|6755947|ref|NP_035811.1|/1.28155e-37/uteroglobin precursor [Mus musculus] 110084 12872 0.01 0.01 0 - 0.080089511 Dnah1 "dynein, axonemal, heavy chain 1" "K10408|1|0.0|8267|mmu:110084|dynein heavy chain, axonemal" - - - "gi|256773234|ref|NP_001028840.1|/0/dynein heavy chain 1, axonemal [Mus musculus]" 639769 2789 0.026666667 0.023333333 -0.192645078 Down 0.080089511 Adh6-ps1 "alcohol dehydrogenase 6 (class V), pseudogene 1" K13952|1|3e-35|153|rno:310903|alcohol dehydrogenase 6 [EC:1.1.1.1] - - - -