Ontology ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count cellular compoment GO:0043025 neuronal cell body 9/79 449/18698 0.0001139 0.018793419 0.014627095 EPHA4/EPHA7/FLRT1/GRIK2/KCNN3/MAPT/NPTXR/NRXN1/STMN2 9 cellular compoment GO:0042734 presynaptic membrane 4/79 79/18698 0.000348697 0.019336138 0.015049498 GRIK2/GRIN2A/NRXN1/RIMS3 4 cellular compoment GO:0097060 synaptic membrane 7/79 317/18698 0.000384387 0.019336138 0.015049498 EPHA4/EPHA7/GRIK2/GRIN2A/MPP2/NRXN1/RIMS3 7 cellular compoment GO:0043198 dendritic shaft 3/79 36/18698 0.000468755 0.019336138 0.015049498 EPHA4/KIRREL3/MPP2 3 cellular compoment GO:0014069 postsynaptic density 5/79 227/18698 0.002744002 0.052530213 0.040884759 CAMK2G/EPHA4/GRIK2/GRIN2A/MPP2 5 cellular compoment GO:0099572 postsynaptic specialization 5/79 229/18698 0.002849502 0.052530213 0.040884759 CAMK2G/EPHA4/GRIK2/GRIN2A/MPP2 5 cellular compoment GO:0043034 costamere 2/79 19/18698 0.002876743 0.052530213 0.040884759 AHNAK/FLNC 2 cellular compoment GO:0098794 postsynapse 7/79 450/18698 0.00291412 0.052530213 0.040884759 CAMK2G/EPHA4/EPHA7/GRIK2/GRIN2A/MAPT/MPP2 7 cellular compoment GO:0032279 asymmetric synapse 5/79 232/18698 0.003013224 0.052530213 0.040884759 CAMK2G/EPHA4/GRIK2/GRIN2A/MPP2 5 cellular compoment GO:0098984 neuron to neuron synapse 5/79 235/18698 0.003183649 0.052530213 0.040884759 CAMK2G/EPHA4/GRIK2/GRIN2A/MPP2 5 cellular compoment GO:0033267 axon part 6/79 353/18698 0.003793068 0.056647591 0.044089353 EPHA4/GRIK2/MAPT/NFASC/NPTXR/STMN2 6 cellular compoment GO:0030426 growth cone 4/79 154/18698 0.004119825 0.056647591 0.044089353 EPHA4/MAPT/NPTXR/STMN2 4 cellular compoment GO:0030427 site of polarized growth 4/79 159/18698 0.004613695 0.058558442 0.045576586 EPHA4/MAPT/NPTXR/STMN2 4 cellular compoment GO:0043235 receptor complex 6/79 374/18698 0.005016645 0.059124744 0.046017344 DDR2/EPHA4/EPHA7/GRIK2/GRIN2A/NTRK3 6 cellular compoment GO:0150034 distal axon 5/79 268/18698 0.00554496 0.06099456 0.04747264 EPHA4/GRIK2/MAPT/NPTXR/STMN2 5 cellular compoment GO:0005925 focal adhesion 6/79 393/18698 0.00635458 0.063937535 0.049763185 AHNAK/DDR2/DIXDC1/FLNC/FLRT1/NFASC 6 cellular compoment GO:0005924 cell-substrate adherens junction 6/79 396/18698 0.006587504 0.063937535 0.049763185 AHNAK/DDR2/DIXDC1/FLNC/FLRT1/NFASC 6 cellular compoment GO:0030055 cell-substrate junction 6/79 401/18698 0.006989458 0.064070031 0.049866308 AHNAK/DDR2/DIXDC1/FLNC/FLRT1/NFASC 6 cellular compoment GO:0098839 postsynaptic density membrane 2/79 32/18698 0.008053291 0.069936475 0.054432216 GRIK2/GRIN2A 2 cellular compoment GO:0099634 postsynaptic specialization membrane 2/79 34/18698 0.00905918 0.074738233 0.05816947 GRIK2/GRIN2A 2 cellular compoment GO:0008328 ionotropic glutamate receptor complex 2/79 49/18698 0.018232166 0.142321706 0.110770323 GRIK2/GRIN2A 2 cellular compoment GO:0098878 neurotransmitter receptor complex 2/79 51/18698 0.019660211 0.142321706 0.110770323 GRIK2/GRIN2A 2 cellular compoment GO:0045211 postsynaptic membrane 4/79 244/18698 0.019838783 0.142321706 0.110770323 EPHA4/EPHA7/GRIK2/GRIN2A 4 cellular compoment GO:0044306 neuron projection terminus 3/79 139/18698 0.021089415 0.14358854 0.111756312 EPHA4/FLRT1/GRIK2 3 cellular compoment GO:0098793 presynapse 5/79 379/18698 0.022136535 0.14358854 0.111756312 EPHA4/GRIK2/GRIN2A/NRXN1/RIMS3 5 cellular compoment GO:0032589 neuron projection membrane 2/79 55/18698 0.022651819 0.14358854 0.111756312 MAPT/MPP2 2 cellular compoment GO:0031252 cell leading edge 5/79 385/18698 0.023496307 0.14358854 0.111756312 GDPD2/MAPT/MCC/MPP2/STMN2 5 cellular compoment GO:0031594 neuromuscular junction 2/79 58/18698 0.025010792 0.147385022 0.114711149 EPHA4/EPHA7 2 cellular compoment GO:0043197 dendritic spine 3/79 153/18698 0.02703066 0.153698177 0.119624738 EPHA4/MAPT/MPP2 3 cellular compoment GO:0044309 neuron spine 3/79 155/18698 0.027945123 0.153698177 0.119624738 EPHA4/MAPT/MPP2 3 biological process GO:0050808 synapse organization 11/77 304/17653 8.03E-08 0.000126652 0.000110506 EPHA4/EPHA7/FLRT1/KIRREL3/MAPT/NFASC/NFIA/NRXN1/NTRK3/SLITRK4/ZNF365 11 biological process GO:0010721 negative regulation of cell development 10/77 301/17653 7.16E-07 0.000564722 0.000492734 DIXDC1/EPHA4/EPHA7/FBLN1/NEXMIF/NTRK3/PBX1/SEMA4A/STMN2/ZNF365 10 biological process GO:0061564 axon development 12/77 497/17653 1.51E-06 0.000668201 0.000583021 EPHA4/EPHA7/KLF4/MAPT/NFASC/NPTX1/NRXN1/NRXN3/NTRK3/SEMA4A/SLITRK4/UNC5D 12 biological process GO:0050768 negative regulation of neurogenesis 9/77 259/17653 1.85E-06 0.000668201 0.000583021 DIXDC1/EPHA4/EPHA7/NEXMIF/NTRK3/PBX1/SEMA4A/STMN2/ZNF365 9 biological process GO:0007612 learning 7/77 136/17653 2.12E-06 0.000668201 0.000583021 BTG2/FOXP2/GRIN2A/MEIS2/NDRG4/NRXN1/NRXN3 7 biological process GO:0051961 negative regulation of nervous system development 9/77 278/17653 3.31E-06 0.000871072 0.000760031 DIXDC1/EPHA4/EPHA7/NEXMIF/NTRK3/PBX1/SEMA4A/STMN2/ZNF365 9 biological process GO:0007409 axonogenesis 11/77 456/17653 4.36E-06 0.000982445 0.000857206 EPHA4/EPHA7/MAPT/NFASC/NPTX1/NRXN1/NRXN3/NTRK3/SEMA4A/SLITRK4/UNC5D 11 biological process GO:0007611 learning or memory 8/77 240/17653 9.74E-06 0.001921763 0.001676783 BTG2/FOXP2/GRIN2A/MAPT/MEIS2/NDRG4/NRXN1/NRXN3 8 biological process GO:0050890 cognition 8/77 277/17653 2.74E-05 0.004605579 0.004018476 BTG2/FOXP2/GRIN2A/MAPT/MEIS2/NDRG4/NRXN1/NRXN3 8 biological process GO:0045665 negative regulation of neuron differentiation 7/77 203/17653 2.92E-05 0.004605579 0.004018476 DIXDC1/EPHA4/EPHA7/PBX1/SEMA4A/STMN2/ZNF365 7 biological process GO:0051963 regulation of synapse assembly 5/77 88/17653 4.09E-05 0.005553434 0.004845502 EPHA7/FLRT1/NRXN1/NTRK3/SLITRK4 5 biological process GO:0050806 positive regulation of synaptic transmission 6/77 146/17653 4.22E-05 0.005553434 0.004845502 EPHA4/GRIK2/GRIN2A/MPP2/NRXN1/RIMS3 6 biological process GO:0007416 synapse assembly 6/77 153/17653 5.49E-05 0.00665982 0.005810849 EPHA7/FLRT1/KIRREL3/NRXN1/NTRK3/SLITRK4 6 biological process GO:0071625 vocalization behavior 3/77 19/17653 7.35E-05 0.007936801 0.006925045 FOXP2/NRXN1/NRXN3 3 biological process GO:0061387 regulation of extent of cell growth 5/77 100/17653 7.54E-05 0.007936801 0.006925045 EPHA4/EPHA7/MAPT/NTRK3/SEMA4A 5 biological process GO:0050807 regulation of synapse organization 6/77 165/17653 8.34E-05 0.008227778 0.00717893 EPHA4/EPHA7/FLRT1/NRXN1/NTRK3/SLITRK4 6 biological process GO:0048167 regulation of synaptic plasticity 6/77 168/17653 9.21E-05 0.008553535 0.00746316 EPHA4/GRIK2/GRIN2A/MAPT/MPP2/RIMS3 6 biological process GO:0007411 axon guidance 7/77 248/17653 0.000103365 0.009024711 0.007874272 EPHA4/EPHA7/NFASC/NRXN1/NRXN3/SEMA4A/UNC5D 7 biological process GO:0097485 neuron projection guidance 7/77 250/17653 0.000108663 0.009024711 0.007874272 EPHA4/EPHA7/NFASC/NRXN1/NRXN3/SEMA4A/UNC5D 7 biological process GO:0050803 regulation of synapse structure or activity 6/77 176/17653 0.000119004 0.009389422 0.008192491 EPHA4/EPHA7/FLRT1/NRXN1/NTRK3/SLITRK4 6 biological process GO:0010975 regulation of neuron projection development 9/77 450/17653 0.000145826 0.010957785 0.009560925 EPHA4/EPHA7/KLF4/MAPT/NDRG4/NTRK3/SEMA4A/STMN2/ZNF365 9 biological process GO:0048679 regulation of axon regeneration 3/77 25/17653 0.000171267 0.012284499 0.010718514 EPHA4/KLF4/NTRK3 3 biological process GO:0051965 positive regulation of synapse assembly 4/77 67/17653 0.000208233 0.014286621 0.012465413 FLRT1/NRXN1/NTRK3/SLITRK4 4 biological process GO:0008306 associative learning 4/77 71/17653 0.000260514 0.01696021 0.014798182 BTG2/GRIN2A/MEIS2/NDRG4 4 biological process GO:0070570 regulation of neuron projection regeneration 3/77 29/17653 0.000268698 0.01696021 0.014798182 EPHA4/KLF4/NTRK3 3 biological process GO:0051962 positive regulation of nervous system development 9/77 493/17653 0.000287354 0.017440186 0.015216973 EPHA4/FLRT1/MAPT/NDRG4/NRXN1/NTRK3/SLITRK4/STMN2/ZNF365 9 biological process GO:0048588 developmental cell growth 6/77 211/17653 0.000317841 0.018576054 0.016208044 EPHA4/EPHA7/FLRT1/MAPT/NTRK3/SEMA4A 6 biological process GO:0010977 negative regulation of neuron projection development 5/77 138/17653 0.000341542 0.019248337 0.016794627 EPHA4/EPHA7/SEMA4A/STMN2/ZNF365 5 biological process GO:0060560 developmental growth involved in morphogenesis 6/77 218/17653 0.00037829 0.020464662 0.017855899 EPHA4/EPHA7/FLRT1/MAPT/NTRK3/SEMA4A 6 biological process GO:0001505 regulation of neurotransmitter levels 7/77 308/17653 0.000389062 0.020464662 0.017855899 GPM6B/GRIN2A/KLF4/MAOA/NRXN1/RIMS3/RORA 7 molecular function GO:0005003 ephrin receptor activity 3/74 19/17548 6.65E-05 0.009797529 0.008118012 EPHA4/EPHA7/NTRK3 3 molecular function GO:0005057 "signal transducer activity, downstream of receptor" 6/74 169/17548 7.87E-05 0.009797529 0.008118012 DDR2/EPHA4/EPHA7/FLRT1/MAPK10/NTRK3 6 molecular function GO:0004702 "signal transducer, downstream of receptor, with serine/threonine kinase activity" 5/74 123/17548 0.000170679 0.010725965 0.008887293 DDR2/EPHA4/EPHA7/MAPK10/NTRK3 5 molecular function GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/74 66/17548 0.000172305 0.010725965 0.008887293 DDR2/EPHA4/EPHA7/NTRK3 4 molecular function GO:0031434 mitogen-activated protein kinase kinase binding 4/74 70/17548 0.000216435 0.010778472 0.008930799 DDR2/EPHA4/EPHA7/NTRK3 4 molecular function GO:0004709 MAP kinase kinase kinase activity 4/74 81/17548 0.000379244 0.014805825 0.012267773 DDR2/EPHA4/EPHA7/NTRK3 4 molecular function GO:0019199 transmembrane receptor protein kinase activity 4/74 83/17548 0.000416228 0.014805825 0.012267773 DDR2/EPHA4/EPHA7/NTRK3 4 molecular function GO:0001228 "transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding" 7/74 417/17548 0.0018621 0.057957849 0.048022568 ESRRG/KLF4/MEIS2/NFIA/PAX9/PBX1/RORA 7 molecular function GO:0005005 transmembrane-ephrin receptor activity 2/74 17/17548 0.002290103 0.063359512 0.052498264 EPHA4/EPHA7 2 molecular function GO:0004970 ionotropic glutamate receptor activity 2/74 19/17548 0.002863808 0.064826202 0.05371353 GRIK2/GRIN2A 2 molecular function GO:0005234 extracellularly glutamate-gated ion channel activity 2/74 19/17548 0.002863808 0.064826202 0.05371353 GRIK2/GRIN2A 2 molecular function GO:0001010 "transcription factor activity, sequence-specific DNA binding transcription factor recruiting" 2/74 20/17548 0.003173349 0.065846988 0.054559331 KLF4/RORA 2 molecular function GO:0045499 chemorepellent activity 2/74 21/17548 0.003497843 0.066997142 0.055512322 EPHA7/SEMA4A 2 molecular function GO:0008013 beta-catenin binding 3/74 82/17548 0.005022122 0.089322034 0.074010225 AMER2/KLF4/RORA 3 molecular function GO:0008066 glutamate receptor activity 2/74 27/17548 0.005751702 0.089510859 0.074166681 GRIK2/GRIN2A 2 molecular function GO:0046875 ephrin receptor binding 2/74 27/17548 0.005751702 0.089510859 0.074166681 EPHA4/EPHA7 2 molecular function GO:0008081 phosphoric diester hydrolase activity 3/74 91/17548 0.006705854 0.096025453 0.079564527 GDPD2/PDE5A/SMPD3 3 molecular function GO:0001134 "transcription factor activity, transcription factor recruiting" 2/74 30/17548 0.007070295 0.096025453 0.079564527 KLF4/RORA 2 molecular function GO:0004713 protein tyrosine kinase activity 4/74 182/17548 0.007327243 0.096025453 0.079564527 DDR2/EPHA4/EPHA7/NTRK3 4 molecular function GO:0000982 "transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding" 6/74 415/17548 0.008081527 0.100615014 0.083367333 BTG2/FOXP2/KLF4/MEIS2/NFIA/PBX1 6 molecular function GO:0031624 ubiquitin conjugating enzyme binding 2/74 34/17548 0.009019761 0.106948592 0.088615193 GRIK2/RNF217 2 molecular function GO:0099094 ligand-gated cation channel activity 3/74 109/17548 0.010980791 0.12104552 0.100295591 GRIK2/GRIN2A/HCN1 3 molecular function GO:0030551 cyclic nucleotide binding 2/74 38/17548 0.011180912 0.12104552 0.100295591 HCN1/PDE5A 2 molecular function GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/74 40/17548 0.012338534 0.12801229 0.106068099 GRIK2/RNF217 2 molecular function GO:0001221 transcription cofactor binding 2/74 41/17548 0.012936205 0.128844605 0.106757736 KLF4/RORA 2 molecular function GO:0005272 sodium channel activity 2/74 45/17548 0.015449993 0.147963395 0.122599136 GRIK2/HCN1 2 molecular function GO:0005267 potassium channel activity 3/74 129/17548 0.017223177 0.150578523 0.124765971 GRIK2/HCN1/KCNN3 3 molecular function GO:0005231 excitatory extracellular ligand-gated ion channel activity 2/74 48/17548 0.017461483 0.150578523 0.124765971 GRIK2/GRIN2A 2 molecular function GO:0004879 nuclear receptor activity 2/74 49/17548 0.018155424 0.150578523 0.124765971 ESRRG/RORA 2 molecular function GO:0098531 "transcription factor activity, direct ligand regulated sequence-specific DNA binding" 2/74 49/17548 0.018155424 0.150578523 0.124765971 ESRRG/RORA 2 kegg hsa04728 Dopaminergic synapse 5月29日 131/7878 0.000101499 0.014615841 0.013141436 818/2788/2903/4128/5602 5 kegg hsa04360 Axon guidance 5月29日 181/7878 0.000459562 0.033088477 0.029750604 818/2043/2045/64218/137970 5 kegg hsa05031 Amphetamine addiction 3月29日 68/7878 0.001914155 0.091879424 0.082610886 818/2903/4128 3 kegg hsa04012 ErbB signaling pathway 3月29日 85/7878 0.003617549 0.13023177 0.117094355 818/1026/5602 3 kegg hsa04713 Circadian entrainment 3月29日 97/7878 0.005242809 0.150992913 0.135761172 818/2788/2903 3 kegg hsa04724 Glutamatergic synapse 3月29日 114/7878 0.008200285 0.189743805 0.170602982 2788/2898/2903 3 kegg hsa04722 Neurotrophin signaling pathway 3月29日 119/7878 0.009223657 0.189743805 0.170602982 818/5602/4916 3 kegg hsa05030 Cocaine addiction 2/29 49/7878 0.013825886 0.248865943 0.223761045 2903/4128 2 kegg hsa04514 Cell adhesion molecules (CAMs) 3月29日 146/7878 0.0160169 0.256270398 0.23041856 23114/9378/9369 3 kegg hsa04934 Cushing syndrome 3月29日 155/7878 0.018769652 0.270282995 0.243017605 818/1026/5087 3 kegg hsa04720 Long-term potentiation 2/29 67/7878 0.024956561 0.29531769 0.26552687 818/2903 2 kegg hsa05034 Alcoholism 3月29日 180/7878 0.02772555 0.29531769 0.26552687 2788/2903/4128 3 kegg hsa05167 Kaposi sarcoma-associated herpesvirus infection 3月29日 186/7878 0.030162523 0.29531769 0.26552687 1026/2788/5602 3 kegg hsa05212 Pancreatic cancer 2/29 75/7878 0.030762259 0.29531769 0.26552687 1026/5602 2 kegg hsa05214 Glioma 2/29 75/7878 0.030762259 0.29531769 0.26552687 818/1026 2 kegg hsa05132 Salmonella infection 2/29 83/7878 0.037050129 0.299565773 0.269346419 2318/5602 2 kegg hsa05205 Proteoglycans in cancer 3月29日 203/7878 0.037668793 0.299565773 0.269346419 818/1026/2318 3 kegg hsa04911 Insulin secretion 2/29 86/7878 0.03952604 0.299565773 0.269346419 818/3782 2 kegg hsa05210 Colorectal cancer 2/29 86/7878 0.03952604 0.299565773 0.269346419 1026/5602 2 kegg hsa04024 cAMP signaling pathway 3月29日 214/7878 0.042995104 0.309564747 0.278336725 818/2903/5602 3 kegg hsa04912 GnRH signaling pathway 2/29 93/7878 0.045541055 0.312281517 0.280779434 818/5602 2