S1 Dataset,,,,,,,,,,,,,,,,, First Author,Year of Publication,Study Period,Country,Region,Species,Forms of Disease,Age of Participants,Study Setting,Treatment Drug,Dose,Numb of Dose,Follow up time,Follow up time groups,Population,Sample size,Case,Reinfection rate Chandiwana SK,1991,1987 -1988,Zimbabwe,Africa,S. haematobium,urogenital,15andbelow,Community,Praziquantel,40,Single,3.5,lessthan12,102,medium,13,0.12745098 Friis H,1997,Not indicated,Zimbabwe,Africa,S. haematobium,urogenital,all,School,Praziquantel,40,Sinlge,12,12andabove,261,medium,54,0.206896552 Garba,2013,2007 -2008,Niger,Africa,S. haematobium,urogenital,15andbelow,School,Praziquantel,40,Double,6,lessthan12,369,medium,44,0.119241192 Garba,2013,2007 -2008,Niger,Africa,S. haematobium,urogenital,15andbelow,School,Praziquantel,40,Double,12,12andabove,211,medium,70,0.331753555 Gyoten J,1992,1986 - 1987,Kenya,Africa,S. haematobium,urogenital,all,Community,Praziquantel,40,Single,12,12andabove,175,medium,47,0.268571 Haumson RS,2018,2014 - 2015,Nigeria,Africa,S. haematobium,urogenital,15andbelow,Community,Praziquantel,40,Single,12,12andabove,272,medium,51,0.1875 Kabuyaya,2017,2015 -2016,South Africa,Africa,S. haematobium,urogenital,15andbelow,School,Praziquantel,40,Single ,5,lessthan12,12,small,1,0.083333333 Kabuyaya,2017,2015 -2016,South Africa,Africa,S. haematobium,urogenital,15andbelow,School,Praziquantel,40,Single ,7,lessthan12,25,small,2,0.08 Lemos,2019,2012 - 2013,Angola,Africa,S. haematobium,urogenital,15andbelow,Community,Praziquantel,40,Single ,6,lessthan12,14,small,12,0.857142857 Mutsaka-Makuvaza,2018,2016 - 2017,Zimbabwe,Africa,S. haematobium,urogenital,15andbelow,Community,Praziquantel,40,Single ,12,12andabove,42,small,13,0.30952381 Mduluza T,2001,Not indicated,Zimbabwe,Africa,S. haematobium,urogenital,15andbelow,School,Praziquantel,40,Multiple,24,12andabove,246,medium,3,0.012195122 Mutapi F,1999,1995 -1996,Zimbabwe,Africa,S. haematobium,urogenital,15andbelow,School,Praziquantel,40,Single,9,lessthan12,140,medium,29,0.207 Ofoezie,2000,Not indicated,Nigeria,Africa,S. haematobium,urogenital,15andbelow,School,Praziquantel,40,Single,3,lessthan12,87,small,8,0.091954023 Ofoezie,2000,Not indicated,Nigeria,Africa,S. haematobium,urogenital,all,School,Praziquantel,40,Single,6,lessthan12,87,small,16,0.183908046 Ofoezie,2000,Not indicated,Nigeria,Africa,S. haematobium,urogenital,all,School,Praziquantel,40,Single,12,12andabove,87,small,32,0.367816092 Senghor,2015,2011 -2012,Senegal,Africa,S. haematobium,urogenital,15andbelow,Community,Praziquantel,40,Single ,6,lessthan12,222,medium,28,0.126126126 Senghor B,2016,2011 - 2012,Senegal,Africa,S. haematobium,urogenital,all,Community,Praziquantel,40,Single,7,lessthan12,592,large,40,0.067567568 Senghor B,2016,2012 - 2013,Senegal,Africa,S. haematobium,urogenital,all,Community,Praziquantel,40,Single,12,12andabove,609,large,66,0.108374384 Senghor B,2016,2012 -2013,Senegal,Africa,S. haematobium,urogenital,all,Community,Praziquantel,40,Single,36,12andabove,606,large,61,0.100660066 Webster,2012,2007 - 2010,Senegal,Africa,S. haematobium,urogenital,15andbelow,Community,Praziquantel,40,Single ,6,lessthan12,92,small,34,0.37 Webster,2012,2007 - 2010,Senegal,Africa,S. haematobium,urogenital,15andbelow,Community,Praziquantel,40,Double,6,12andabove,92,small,77,0.837 Olliaro,2011,2005 - 2007,Philippines,Nonafrica,S.japonicum,intestinal,all,School,Praziquantel,40,Single ,12,12andabove,100,medium,38,0.38 Olliaro,2011,2005 -2007,Philippines,Nonafrica,S.japonicum,intestinal,all,School,Praziquantel,60,Single ,12,12andabove,101,medium,34,0.336633663 Belizario,2008,Not indicated,Philippines,Nonafrica,S.japonicum,intestinal,all,School,Praziquantel,60,Single,6,lessthan12,101,medium,28,0.277227723 Belizario,2008,Not indicated,Philippines,Nonafrica,S.japonicum,intestinal,all,School,Praziquantel,60,Single,12,12andabove,101,medium,49,0.485148515 Belizario,2008,Not indicated,Philippines,Nonafrica,S.japonicum,intestinal,all,School,Praziquantel,40,Single,6,lessthan12,102,medium,26,0.254901961 Belizario,2008,Not indicated,Philippines,Nonafrica,S.japonicum,intestinal,all,School,Praziquantel,40,Single,12,12andabove,102,medium,64,0.62745098 Jiz M,2009,2002 -2003,Philippines,Nonafrica,S.japonicum,intestinal,all,Community,Praziquantel,60,Single,6,lessthan12,553,large,318,0.575045208 Jiz M,2009,2002 - 2003,Philippines,Nonafrica,S.japonicum,intestinal,all,Community,Praziquantel,60,Single,12,12andabove,553,large,431,0.779385172 Li YS,2000,1996 - 1998,China,Nonafrica,S.japonicum,intestinal,all,Community,Praziquantel,40,Single,24,12andabove,54,small,16,0.296296296 Zhaosong Z,1997,1993 - 1993,China,Nonafrica,S.japonicum,intestinal,15andbelow,Community,Praziquantel,60,Single,9,lessthan12,60,small,12,0.2 Zhaosong Z,1997,1993 -1993,China,Nonafrica,S.japonicum,intestinal,all,Community,Praziquantel,60,Single,9,lessthan12,111,medium,42,0.378378378 Olliaro,2011,2005 -2007,Brazil,Nonafrica,S.mansoni,intestinal,all,Community,Praziquantel,40,Single ,12,12andabove,239,medium,96,0.40167364 Olliaro,2011,2005 -2007,Brazil,Nonafrica,S.mansoni,intestinal,all,Community,Praziquantel,60,Single ,12,12andabove,517,large,93,0.179883946 Olliaro,2011,2005 -2007,Tanzania,Africa,S.mansoni,intestinal,all,School,Praziquantel,40,Single ,12,12andabove,219,medium,103,0.470319635 Olliaro,2011,2005 -2007,Tanzania,Africa,S.mansoni,intestinal,all,School,Praziquantel,60,Single ,12,12andabove,300,medium,111,0.37 de Lima (Costa),1993,1974 - 1987,Brazil,Nonafrica,S.mansoni,intestinal,all,Community,Oxamniquine,20,Multiple,156,12andabove,203,medium,110,0.541871921 de Moira AP,2010,Not indicated,Uganda,Africa,S.mansoni,intestinal,all,Community,Praziquantel,40,Double,12,12andabove,212,medium,106,0.5 Egesa M,2018,2011 - 2012,Uganda,Africa,S.mansoni,intestinal,all,Community,Praziquantel,40,Double,12,12andabove,186,medium,154,0.827956989 Favre,2015,2009 - 2010,Brazil,Nonafrica,S.mansoni,intestinal,15andbelow,School,Praziquantel,60,Single ,12,12andabove,116,medium,31,0.267241379 Favre,2015,2009 - 2010,Brazil,Nonafrica,S.mansoni,intestinal,15andbelow,Community,Praziquantel,60,Single ,12,12andabove,324,medium,64,0.197530864 Friis H,1997,Not indicated,Zimbabwe,Africa,S.mansoni,intestinal,all,School,Praziquantel,40,Sinlge,12,12andabove,261,medium,71,0.272030651 Garba,2013,2007 - 2008,Niger,Africa,S.mansoni,intestinal,15andbelow,School,Praziquantel,40,Double,6,lessthan12,96,small,56,0.583333333 Garba,2013,2007 - 2008,Niger,Africa,S.mansoni,intestinal,15andbelow,School,Praziquantel,40,Double,12,12andabove,93,small,59,0.634408602 Gazzinelli A,2017,Not indicated,Brazil,Nonafrica,S.mansoni,intestinal,15andbelow,Community,Praziquantel,60,Single,12,12andabove,581,large,140,0.240964 Munisi,2017,2015 - 2016,Tanzania,Africa,S.mansoni,intestinal,all,School,Praziquantel,40,Single ,5,less than 12,112,medium,74,0.660714286 Munisi,2017,2015 - 2016,Tanzania,Africa,S.mansoni,intestinal,all,School,Praziquantel,40,Double,5,lessthan12,150,medium,102,0.68 Munisi,2017,2015 - 2016,Tanzania,Africa,S.mansoni,intestinal,all,School,Praziquantel,40,Single ,8,lessthan12,121,medium,100,0.826446281 Munisi,2017,2015 - 2016,Tanzania,Africa,S.mansoni,intestinal,all,School,Praziquantel,40,Double,8,lessthan12,148,medium,114,0.77027027 Nalugwa,2015,Not indicated,Uganda ,Africa,S.mansoni,intestinal,15andbelow,Community,Praziquantel,40,Single,8,lessthan12,236,medium,92,0.389830508 Nalugwa,2015,Not indicated,Uganda ,Africa,S.mansoni,intestinal,15andbelow,Community,Praziquantel,40,Double,8,lessthan12,227,medium,114,0.502202643 Reis EAG,2006,Not indicated,Brazil,Nonafrica,S.mansoni,intestinal,all,School,Oxamniquine,20,Single,6,lessthan12,365,medium,57,0.156164384 Satti MZ,1996,Not indicated,Sudan,Africa,S.mansoni,intestinal,all,Community,Praziquantel,40,Double,12,12andabove,11,small,3,0.272727273 Woldegerima,2019,2017 - 2018,Ethopia,Africa,S.mansoni,intestinal,15andbelow,School,Praziquantel,40,Double,6,lessthan12,72,small,10,0.138888889